data_8ZGO
# 
_entry.id   8ZGO 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8ZGO         pdb_00008zgo 10.2210/pdb8zgo/pdb 
WWPDB D_1300046880 ?            ?                   
EMDB  EMD-60085    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-05-14 ? 
2 'EM metadata'     1 0 2025-05-14 ? 
3 'Additional map'  1 0 2025-05-14 1 
4 FSC               1 0 2025-05-14 ? 
5 'Half map'        1 0 2025-05-14 1 
6 'Half map'        1 0 2025-05-14 2 
7 Image             1 0 2025-05-14 ? 
8 'Primary map'     1 0 2025-05-14 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1 1 'Structure model' repository 'Initial release' ? ? 
2 2 'EM metadata'     repository 'Initial release' ? ? 
3 3 'Additional map'  repository 'Initial release' ? ? 
4 4 FSC               repository 'Initial release' ? ? 
5 5 'Half map'        repository 'Initial release' ? ? 
6 6 'Half map'        repository 'Initial release' ? ? 
7 7 Image             repository 'Initial release' ? ? 
8 8 'Primary map'     repository 'Initial release' ? ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8ZGO 
_pdbx_database_status.recvd_initial_deposition_date   2024-05-09 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    CAPRI 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        
'CryoEM structure of monomeric quinol dependent nitric oxide reductase from Neisseria meningitidis' 
_pdbx_database_related.db_id          EMD-60085 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              ttosha@sci.u-hyogo.ac.jp 
_pdbx_contact_author.name_first         Takehiko 
_pdbx_contact_author.name_last          Tosha 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-8971-0759 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Gopalasingam, C.C.' 1 ? 
'Shiro, Y.'          2 ? 
'Tosha, T.'          3 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
'CryoEM structure of monomeric quinol dependent nitric oxide reductase from Neisseria meningitidis' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Gopalasingam, C.C.' 1 ? 
primary 'Shiro, Y.'          2 ? 
primary 'Tosha, T.'          3 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Nitric-oxide reductase'          84389.211 1  1.7.99.7 ? ? ? 
2 non-polymer syn 'PROTOPORPHYRIN IX CONTAINING FE' 616.487   2  ?        ? ? ? 
3 non-polymer syn 'FE (III) ION'                    55.845    1  ?        ? ? ? 
4 non-polymer syn 'CALCIUM ION'                     40.078    1  ?        ? ? ? 
5 water       nat water                             18.015    32 ?        ? ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MGQYKKLWYLLFAVLAVCFTILGYMGSEVYKKAPPYPEQVVSASGKVLMAKDDILAGQSAWQTTGGMEVGSVLGHGAYQA
PDWTADWLHRELSAWLDLTAQQTYGKKFDEVSPEEQAVLKTRLADEYRNQSRIKEDGSVVISDTRVKAIESILPYYHGVY
GDDPALQTTREHFAMKNNTLPSQEAREKLFDFFFWTSWSASTNRPDETFTYTNNWPHEPLINNVPTTENYMWSFTSVVLL
LMGIGLLMWGYSFLTKHEEVEVPTEDPISKVQLTPSQKALGKYVFLTVALFVVQVLLGGLTAHYTVEGQGFYGIDEALGF
EMSDWFPYALTRTWHIQSAIFWIATGFLTAGLFLAPIVNGGKDPKFQRAGVNFLYIALFIVVGGSYAGNFFALTHILPPE
FNFWFGHQGYEYLDLGRFWQLLLMVGLLLWLFLMLRCTVSAFKEKGVDKNLLAIFVASMVGVGVFYAPGLFYGEKSPIAV
MEYWRWWVVHLWVEGFFEVFATAAFAFVFYNMGFVRRSTATASTLAAAAIFMLGGVPGTLHHLYFSGSTSASMAIGACFS
ALEVVPLVLLGREAYEHWSYQHLSEWAKRLRWPLMCFVAVAFWNMIGAGVFGFLINPPISLFYIQGLNTSAVHAHAALFG
VYGFLALGFVLLVARYLKPNVQFDDKLMTWGFWLLNGGLVGMIAISLLPVGVIQAYASITHGLWYARSEEFLQMEILDTL
RWVRTAADLIFIGGAICVAIQATKIVFGRDK
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MGQYKKLWYLLFAVLAVCFTILGYMGSEVYKKAPPYPEQVVSASGKVLMAKDDILAGQSAWQTTGGMEVGSVLGHGAYQA
PDWTADWLHRELSAWLDLTAQQTYGKKFDEVSPEEQAVLKTRLADEYRNQSRIKEDGSVVISDTRVKAIESILPYYHGVY
GDDPALQTTREHFAMKNNTLPSQEAREKLFDFFFWTSWSASTNRPDETFTYTNNWPHEPLINNVPTTENYMWSFTSVVLL
LMGIGLLMWGYSFLTKHEEVEVPTEDPISKVQLTPSQKALGKYVFLTVALFVVQVLLGGLTAHYTVEGQGFYGIDEALGF
EMSDWFPYALTRTWHIQSAIFWIATGFLTAGLFLAPIVNGGKDPKFQRAGVNFLYIALFIVVGGSYAGNFFALTHILPPE
FNFWFGHQGYEYLDLGRFWQLLLMVGLLLWLFLMLRCTVSAFKEKGVDKNLLAIFVASMVGVGVFYAPGLFYGEKSPIAV
MEYWRWWVVHLWVEGFFEVFATAAFAFVFYNMGFVRRSTATASTLAAAAIFMLGGVPGTLHHLYFSGSTSASMAIGACFS
ALEVVPLVLLGREAYEHWSYQHLSEWAKRLRWPLMCFVAVAFWNMIGAGVFGFLINPPISLFYIQGLNTSAVHAHAALFG
VYGFLALGFVLLVARYLKPNVQFDDKLMTWGFWLLNGGLVGMIAISLLPVGVIQAYASITHGLWYARSEEFLQMEILDTL
RWVRTAADLIFIGGAICVAIQATKIVFGRDK
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 'PROTOPORPHYRIN IX CONTAINING FE' HEM 
3 'FE (III) ION'                    FE  
4 'CALCIUM ION'                     CA  
5 water                             HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   GLY n 
1 3   GLN n 
1 4   TYR n 
1 5   LYS n 
1 6   LYS n 
1 7   LEU n 
1 8   TRP n 
1 9   TYR n 
1 10  LEU n 
1 11  LEU n 
1 12  PHE n 
1 13  ALA n 
1 14  VAL n 
1 15  LEU n 
1 16  ALA n 
1 17  VAL n 
1 18  CYS n 
1 19  PHE n 
1 20  THR n 
1 21  ILE n 
1 22  LEU n 
1 23  GLY n 
1 24  TYR n 
1 25  MET n 
1 26  GLY n 
1 27  SER n 
1 28  GLU n 
1 29  VAL n 
1 30  TYR n 
1 31  LYS n 
1 32  LYS n 
1 33  ALA n 
1 34  PRO n 
1 35  PRO n 
1 36  TYR n 
1 37  PRO n 
1 38  GLU n 
1 39  GLN n 
1 40  VAL n 
1 41  VAL n 
1 42  SER n 
1 43  ALA n 
1 44  SER n 
1 45  GLY n 
1 46  LYS n 
1 47  VAL n 
1 48  LEU n 
1 49  MET n 
1 50  ALA n 
1 51  LYS n 
1 52  ASP n 
1 53  ASP n 
1 54  ILE n 
1 55  LEU n 
1 56  ALA n 
1 57  GLY n 
1 58  GLN n 
1 59  SER n 
1 60  ALA n 
1 61  TRP n 
1 62  GLN n 
1 63  THR n 
1 64  THR n 
1 65  GLY n 
1 66  GLY n 
1 67  MET n 
1 68  GLU n 
1 69  VAL n 
1 70  GLY n 
1 71  SER n 
1 72  VAL n 
1 73  LEU n 
1 74  GLY n 
1 75  HIS n 
1 76  GLY n 
1 77  ALA n 
1 78  TYR n 
1 79  GLN n 
1 80  ALA n 
1 81  PRO n 
1 82  ASP n 
1 83  TRP n 
1 84  THR n 
1 85  ALA n 
1 86  ASP n 
1 87  TRP n 
1 88  LEU n 
1 89  HIS n 
1 90  ARG n 
1 91  GLU n 
1 92  LEU n 
1 93  SER n 
1 94  ALA n 
1 95  TRP n 
1 96  LEU n 
1 97  ASP n 
1 98  LEU n 
1 99  THR n 
1 100 ALA n 
1 101 GLN n 
1 102 GLN n 
1 103 THR n 
1 104 TYR n 
1 105 GLY n 
1 106 LYS n 
1 107 LYS n 
1 108 PHE n 
1 109 ASP n 
1 110 GLU n 
1 111 VAL n 
1 112 SER n 
1 113 PRO n 
1 114 GLU n 
1 115 GLU n 
1 116 GLN n 
1 117 ALA n 
1 118 VAL n 
1 119 LEU n 
1 120 LYS n 
1 121 THR n 
1 122 ARG n 
1 123 LEU n 
1 124 ALA n 
1 125 ASP n 
1 126 GLU n 
1 127 TYR n 
1 128 ARG n 
1 129 ASN n 
1 130 GLN n 
1 131 SER n 
1 132 ARG n 
1 133 ILE n 
1 134 LYS n 
1 135 GLU n 
1 136 ASP n 
1 137 GLY n 
1 138 SER n 
1 139 VAL n 
1 140 VAL n 
1 141 ILE n 
1 142 SER n 
1 143 ASP n 
1 144 THR n 
1 145 ARG n 
1 146 VAL n 
1 147 LYS n 
1 148 ALA n 
1 149 ILE n 
1 150 GLU n 
1 151 SER n 
1 152 ILE n 
1 153 LEU n 
1 154 PRO n 
1 155 TYR n 
1 156 TYR n 
1 157 HIS n 
1 158 GLY n 
1 159 VAL n 
1 160 TYR n 
1 161 GLY n 
1 162 ASP n 
1 163 ASP n 
1 164 PRO n 
1 165 ALA n 
1 166 LEU n 
1 167 GLN n 
1 168 THR n 
1 169 THR n 
1 170 ARG n 
1 171 GLU n 
1 172 HIS n 
1 173 PHE n 
1 174 ALA n 
1 175 MET n 
1 176 LYS n 
1 177 ASN n 
1 178 ASN n 
1 179 THR n 
1 180 LEU n 
1 181 PRO n 
1 182 SER n 
1 183 GLN n 
1 184 GLU n 
1 185 ALA n 
1 186 ARG n 
1 187 GLU n 
1 188 LYS n 
1 189 LEU n 
1 190 PHE n 
1 191 ASP n 
1 192 PHE n 
1 193 PHE n 
1 194 PHE n 
1 195 TRP n 
1 196 THR n 
1 197 SER n 
1 198 TRP n 
1 199 SER n 
1 200 ALA n 
1 201 SER n 
1 202 THR n 
1 203 ASN n 
1 204 ARG n 
1 205 PRO n 
1 206 ASP n 
1 207 GLU n 
1 208 THR n 
1 209 PHE n 
1 210 THR n 
1 211 TYR n 
1 212 THR n 
1 213 ASN n 
1 214 ASN n 
1 215 TRP n 
1 216 PRO n 
1 217 HIS n 
1 218 GLU n 
1 219 PRO n 
1 220 LEU n 
1 221 ILE n 
1 222 ASN n 
1 223 ASN n 
1 224 VAL n 
1 225 PRO n 
1 226 THR n 
1 227 THR n 
1 228 GLU n 
1 229 ASN n 
1 230 TYR n 
1 231 MET n 
1 232 TRP n 
1 233 SER n 
1 234 PHE n 
1 235 THR n 
1 236 SER n 
1 237 VAL n 
1 238 VAL n 
1 239 LEU n 
1 240 LEU n 
1 241 LEU n 
1 242 MET n 
1 243 GLY n 
1 244 ILE n 
1 245 GLY n 
1 246 LEU n 
1 247 LEU n 
1 248 MET n 
1 249 TRP n 
1 250 GLY n 
1 251 TYR n 
1 252 SER n 
1 253 PHE n 
1 254 LEU n 
1 255 THR n 
1 256 LYS n 
1 257 HIS n 
1 258 GLU n 
1 259 GLU n 
1 260 VAL n 
1 261 GLU n 
1 262 VAL n 
1 263 PRO n 
1 264 THR n 
1 265 GLU n 
1 266 ASP n 
1 267 PRO n 
1 268 ILE n 
1 269 SER n 
1 270 LYS n 
1 271 VAL n 
1 272 GLN n 
1 273 LEU n 
1 274 THR n 
1 275 PRO n 
1 276 SER n 
1 277 GLN n 
1 278 LYS n 
1 279 ALA n 
1 280 LEU n 
1 281 GLY n 
1 282 LYS n 
1 283 TYR n 
1 284 VAL n 
1 285 PHE n 
1 286 LEU n 
1 287 THR n 
1 288 VAL n 
1 289 ALA n 
1 290 LEU n 
1 291 PHE n 
1 292 VAL n 
1 293 VAL n 
1 294 GLN n 
1 295 VAL n 
1 296 LEU n 
1 297 LEU n 
1 298 GLY n 
1 299 GLY n 
1 300 LEU n 
1 301 THR n 
1 302 ALA n 
1 303 HIS n 
1 304 TYR n 
1 305 THR n 
1 306 VAL n 
1 307 GLU n 
1 308 GLY n 
1 309 GLN n 
1 310 GLY n 
1 311 PHE n 
1 312 TYR n 
1 313 GLY n 
1 314 ILE n 
1 315 ASP n 
1 316 GLU n 
1 317 ALA n 
1 318 LEU n 
1 319 GLY n 
1 320 PHE n 
1 321 GLU n 
1 322 MET n 
1 323 SER n 
1 324 ASP n 
1 325 TRP n 
1 326 PHE n 
1 327 PRO n 
1 328 TYR n 
1 329 ALA n 
1 330 LEU n 
1 331 THR n 
1 332 ARG n 
1 333 THR n 
1 334 TRP n 
1 335 HIS n 
1 336 ILE n 
1 337 GLN n 
1 338 SER n 
1 339 ALA n 
1 340 ILE n 
1 341 PHE n 
1 342 TRP n 
1 343 ILE n 
1 344 ALA n 
1 345 THR n 
1 346 GLY n 
1 347 PHE n 
1 348 LEU n 
1 349 THR n 
1 350 ALA n 
1 351 GLY n 
1 352 LEU n 
1 353 PHE n 
1 354 LEU n 
1 355 ALA n 
1 356 PRO n 
1 357 ILE n 
1 358 VAL n 
1 359 ASN n 
1 360 GLY n 
1 361 GLY n 
1 362 LYS n 
1 363 ASP n 
1 364 PRO n 
1 365 LYS n 
1 366 PHE n 
1 367 GLN n 
1 368 ARG n 
1 369 ALA n 
1 370 GLY n 
1 371 VAL n 
1 372 ASN n 
1 373 PHE n 
1 374 LEU n 
1 375 TYR n 
1 376 ILE n 
1 377 ALA n 
1 378 LEU n 
1 379 PHE n 
1 380 ILE n 
1 381 VAL n 
1 382 VAL n 
1 383 GLY n 
1 384 GLY n 
1 385 SER n 
1 386 TYR n 
1 387 ALA n 
1 388 GLY n 
1 389 ASN n 
1 390 PHE n 
1 391 PHE n 
1 392 ALA n 
1 393 LEU n 
1 394 THR n 
1 395 HIS n 
1 396 ILE n 
1 397 LEU n 
1 398 PRO n 
1 399 PRO n 
1 400 GLU n 
1 401 PHE n 
1 402 ASN n 
1 403 PHE n 
1 404 TRP n 
1 405 PHE n 
1 406 GLY n 
1 407 HIS n 
1 408 GLN n 
1 409 GLY n 
1 410 TYR n 
1 411 GLU n 
1 412 TYR n 
1 413 LEU n 
1 414 ASP n 
1 415 LEU n 
1 416 GLY n 
1 417 ARG n 
1 418 PHE n 
1 419 TRP n 
1 420 GLN n 
1 421 LEU n 
1 422 LEU n 
1 423 LEU n 
1 424 MET n 
1 425 VAL n 
1 426 GLY n 
1 427 LEU n 
1 428 LEU n 
1 429 LEU n 
1 430 TRP n 
1 431 LEU n 
1 432 PHE n 
1 433 LEU n 
1 434 MET n 
1 435 LEU n 
1 436 ARG n 
1 437 CYS n 
1 438 THR n 
1 439 VAL n 
1 440 SER n 
1 441 ALA n 
1 442 PHE n 
1 443 LYS n 
1 444 GLU n 
1 445 LYS n 
1 446 GLY n 
1 447 VAL n 
1 448 ASP n 
1 449 LYS n 
1 450 ASN n 
1 451 LEU n 
1 452 LEU n 
1 453 ALA n 
1 454 ILE n 
1 455 PHE n 
1 456 VAL n 
1 457 ALA n 
1 458 SER n 
1 459 MET n 
1 460 VAL n 
1 461 GLY n 
1 462 VAL n 
1 463 GLY n 
1 464 VAL n 
1 465 PHE n 
1 466 TYR n 
1 467 ALA n 
1 468 PRO n 
1 469 GLY n 
1 470 LEU n 
1 471 PHE n 
1 472 TYR n 
1 473 GLY n 
1 474 GLU n 
1 475 LYS n 
1 476 SER n 
1 477 PRO n 
1 478 ILE n 
1 479 ALA n 
1 480 VAL n 
1 481 MET n 
1 482 GLU n 
1 483 TYR n 
1 484 TRP n 
1 485 ARG n 
1 486 TRP n 
1 487 TRP n 
1 488 VAL n 
1 489 VAL n 
1 490 HIS n 
1 491 LEU n 
1 492 TRP n 
1 493 VAL n 
1 494 GLU n 
1 495 GLY n 
1 496 PHE n 
1 497 PHE n 
1 498 GLU n 
1 499 VAL n 
1 500 PHE n 
1 501 ALA n 
1 502 THR n 
1 503 ALA n 
1 504 ALA n 
1 505 PHE n 
1 506 ALA n 
1 507 PHE n 
1 508 VAL n 
1 509 PHE n 
1 510 TYR n 
1 511 ASN n 
1 512 MET n 
1 513 GLY n 
1 514 PHE n 
1 515 VAL n 
1 516 ARG n 
1 517 ARG n 
1 518 SER n 
1 519 THR n 
1 520 ALA n 
1 521 THR n 
1 522 ALA n 
1 523 SER n 
1 524 THR n 
1 525 LEU n 
1 526 ALA n 
1 527 ALA n 
1 528 ALA n 
1 529 ALA n 
1 530 ILE n 
1 531 PHE n 
1 532 MET n 
1 533 LEU n 
1 534 GLY n 
1 535 GLY n 
1 536 VAL n 
1 537 PRO n 
1 538 GLY n 
1 539 THR n 
1 540 LEU n 
1 541 HIS n 
1 542 HIS n 
1 543 LEU n 
1 544 TYR n 
1 545 PHE n 
1 546 SER n 
1 547 GLY n 
1 548 SER n 
1 549 THR n 
1 550 SER n 
1 551 ALA n 
1 552 SER n 
1 553 MET n 
1 554 ALA n 
1 555 ILE n 
1 556 GLY n 
1 557 ALA n 
1 558 CYS n 
1 559 PHE n 
1 560 SER n 
1 561 ALA n 
1 562 LEU n 
1 563 GLU n 
1 564 VAL n 
1 565 VAL n 
1 566 PRO n 
1 567 LEU n 
1 568 VAL n 
1 569 LEU n 
1 570 LEU n 
1 571 GLY n 
1 572 ARG n 
1 573 GLU n 
1 574 ALA n 
1 575 TYR n 
1 576 GLU n 
1 577 HIS n 
1 578 TRP n 
1 579 SER n 
1 580 TYR n 
1 581 GLN n 
1 582 HIS n 
1 583 LEU n 
1 584 SER n 
1 585 GLU n 
1 586 TRP n 
1 587 ALA n 
1 588 LYS n 
1 589 ARG n 
1 590 LEU n 
1 591 ARG n 
1 592 TRP n 
1 593 PRO n 
1 594 LEU n 
1 595 MET n 
1 596 CYS n 
1 597 PHE n 
1 598 VAL n 
1 599 ALA n 
1 600 VAL n 
1 601 ALA n 
1 602 PHE n 
1 603 TRP n 
1 604 ASN n 
1 605 MET n 
1 606 ILE n 
1 607 GLY n 
1 608 ALA n 
1 609 GLY n 
1 610 VAL n 
1 611 PHE n 
1 612 GLY n 
1 613 PHE n 
1 614 LEU n 
1 615 ILE n 
1 616 ASN n 
1 617 PRO n 
1 618 PRO n 
1 619 ILE n 
1 620 SER n 
1 621 LEU n 
1 622 PHE n 
1 623 TYR n 
1 624 ILE n 
1 625 GLN n 
1 626 GLY n 
1 627 LEU n 
1 628 ASN n 
1 629 THR n 
1 630 SER n 
1 631 ALA n 
1 632 VAL n 
1 633 HIS n 
1 634 ALA n 
1 635 HIS n 
1 636 ALA n 
1 637 ALA n 
1 638 LEU n 
1 639 PHE n 
1 640 GLY n 
1 641 VAL n 
1 642 TYR n 
1 643 GLY n 
1 644 PHE n 
1 645 LEU n 
1 646 ALA n 
1 647 LEU n 
1 648 GLY n 
1 649 PHE n 
1 650 VAL n 
1 651 LEU n 
1 652 LEU n 
1 653 VAL n 
1 654 ALA n 
1 655 ARG n 
1 656 TYR n 
1 657 LEU n 
1 658 LYS n 
1 659 PRO n 
1 660 ASN n 
1 661 VAL n 
1 662 GLN n 
1 663 PHE n 
1 664 ASP n 
1 665 ASP n 
1 666 LYS n 
1 667 LEU n 
1 668 MET n 
1 669 THR n 
1 670 TRP n 
1 671 GLY n 
1 672 PHE n 
1 673 TRP n 
1 674 LEU n 
1 675 LEU n 
1 676 ASN n 
1 677 GLY n 
1 678 GLY n 
1 679 LEU n 
1 680 VAL n 
1 681 GLY n 
1 682 MET n 
1 683 ILE n 
1 684 ALA n 
1 685 ILE n 
1 686 SER n 
1 687 LEU n 
1 688 LEU n 
1 689 PRO n 
1 690 VAL n 
1 691 GLY n 
1 692 VAL n 
1 693 ILE n 
1 694 GLN n 
1 695 ALA n 
1 696 TYR n 
1 697 ALA n 
1 698 SER n 
1 699 ILE n 
1 700 THR n 
1 701 HIS n 
1 702 GLY n 
1 703 LEU n 
1 704 TRP n 
1 705 TYR n 
1 706 ALA n 
1 707 ARG n 
1 708 SER n 
1 709 GLU n 
1 710 GLU n 
1 711 PHE n 
1 712 LEU n 
1 713 GLN n 
1 714 MET n 
1 715 GLU n 
1 716 ILE n 
1 717 LEU n 
1 718 ASP n 
1 719 THR n 
1 720 LEU n 
1 721 ARG n 
1 722 TRP n 
1 723 VAL n 
1 724 ARG n 
1 725 THR n 
1 726 ALA n 
1 727 ALA n 
1 728 ASP n 
1 729 LEU n 
1 730 ILE n 
1 731 PHE n 
1 732 ILE n 
1 733 GLY n 
1 734 GLY n 
1 735 ALA n 
1 736 ILE n 
1 737 CYS n 
1 738 VAL n 
1 739 ALA n 
1 740 ILE n 
1 741 GLN n 
1 742 ALA n 
1 743 THR n 
1 744 LYS n 
1 745 ILE n 
1 746 VAL n 
1 747 PHE n 
1 748 GLY n 
1 749 ARG n 
1 750 ASP n 
1 751 LYS n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   751 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 'norB, NMO_1451' 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Neisseria meningitidis alpha14' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     662598 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli BL21(DE3)' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     469008 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               'BL21(DE3)' 
_entity_src_gen.pdbx_host_org_variant              C41 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                           ?    'C3 H7 N O2'       89.093  
ARG 'L-peptide linking' y ARGININE                          ?    'C6 H15 N4 O2 1'   175.209 
ASN 'L-peptide linking' y ASPARAGINE                        ?    'C4 H8 N2 O3'      132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                   ?    'C4 H7 N O4'       133.103 
CA  non-polymer         . 'CALCIUM ION'                     ?    'Ca 2'             40.078  
CYS 'L-peptide linking' y CYSTEINE                          ?    'C3 H7 N O2 S'     121.158 
FE  non-polymer         . 'FE (III) ION'                    ?    'Fe 3'             55.845  
GLN 'L-peptide linking' y GLUTAMINE                         ?    'C5 H10 N2 O3'     146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                   ?    'C5 H9 N O4'       147.129 
GLY 'peptide linking'   y GLYCINE                           ?    'C2 H5 N O2'       75.067  
HEM non-polymer         . 'PROTOPORPHYRIN IX CONTAINING FE' HEME 'C34 H32 Fe N4 O4' 616.487 
HIS 'L-peptide linking' y HISTIDINE                         ?    'C6 H10 N3 O2 1'   156.162 
HOH non-polymer         . WATER                             ?    'H2 O'             18.015  
ILE 'L-peptide linking' y ISOLEUCINE                        ?    'C6 H13 N O2'      131.173 
LEU 'L-peptide linking' y LEUCINE                           ?    'C6 H13 N O2'      131.173 
LYS 'L-peptide linking' y LYSINE                            ?    'C6 H15 N2 O2 1'   147.195 
MET 'L-peptide linking' y METHIONINE                        ?    'C5 H11 N O2 S'    149.211 
PHE 'L-peptide linking' y PHENYLALANINE                     ?    'C9 H11 N O2'      165.189 
PRO 'L-peptide linking' y PROLINE                           ?    'C5 H9 N O2'       115.130 
SER 'L-peptide linking' y SERINE                            ?    'C3 H7 N O3'       105.093 
THR 'L-peptide linking' y THREONINE                         ?    'C4 H9 N O3'       119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                        ?    'C11 H12 N2 O2'    204.225 
TYR 'L-peptide linking' y TYROSINE                          ?    'C9 H11 N O3'      181.189 
VAL 'L-peptide linking' y VALINE                            ?    'C5 H11 N O2'      117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   1   MET MET A . n 
A 1 2   GLY 2   2   2   GLY GLY A . n 
A 1 3   GLN 3   3   3   GLN GLN A . n 
A 1 4   TYR 4   4   4   TYR TYR A . n 
A 1 5   LYS 5   5   5   LYS LYS A . n 
A 1 6   LYS 6   6   6   LYS LYS A . n 
A 1 7   LEU 7   7   7   LEU LEU A . n 
A 1 8   TRP 8   8   8   TRP TRP A . n 
A 1 9   TYR 9   9   9   TYR TYR A . n 
A 1 10  LEU 10  10  10  LEU LEU A . n 
A 1 11  LEU 11  11  11  LEU LEU A . n 
A 1 12  PHE 12  12  12  PHE PHE A . n 
A 1 13  ALA 13  13  13  ALA ALA A . n 
A 1 14  VAL 14  14  14  VAL VAL A . n 
A 1 15  LEU 15  15  15  LEU LEU A . n 
A 1 16  ALA 16  16  16  ALA ALA A . n 
A 1 17  VAL 17  17  17  VAL VAL A . n 
A 1 18  CYS 18  18  18  CYS CYS A . n 
A 1 19  PHE 19  19  19  PHE PHE A . n 
A 1 20  THR 20  20  20  THR THR A . n 
A 1 21  ILE 21  21  21  ILE ILE A . n 
A 1 22  LEU 22  22  22  LEU LEU A . n 
A 1 23  GLY 23  23  23  GLY GLY A . n 
A 1 24  TYR 24  24  24  TYR TYR A . n 
A 1 25  MET 25  25  25  MET MET A . n 
A 1 26  GLY 26  26  26  GLY GLY A . n 
A 1 27  SER 27  27  27  SER SER A . n 
A 1 28  GLU 28  28  28  GLU GLU A . n 
A 1 29  VAL 29  29  29  VAL VAL A . n 
A 1 30  TYR 30  30  30  TYR TYR A . n 
A 1 31  LYS 31  31  31  LYS LYS A . n 
A 1 32  LYS 32  32  32  LYS LYS A . n 
A 1 33  ALA 33  33  33  ALA ALA A . n 
A 1 34  PRO 34  34  34  PRO PRO A . n 
A 1 35  PRO 35  35  35  PRO PRO A . n 
A 1 36  TYR 36  36  36  TYR TYR A . n 
A 1 37  PRO 37  37  37  PRO PRO A . n 
A 1 38  GLU 38  38  38  GLU GLU A . n 
A 1 39  GLN 39  39  39  GLN GLN A . n 
A 1 40  VAL 40  40  40  VAL VAL A . n 
A 1 41  VAL 41  41  41  VAL VAL A . n 
A 1 42  SER 42  42  42  SER SER A . n 
A 1 43  ALA 43  43  43  ALA ALA A . n 
A 1 44  SER 44  44  44  SER SER A . n 
A 1 45  GLY 45  45  45  GLY GLY A . n 
A 1 46  LYS 46  46  46  LYS LYS A . n 
A 1 47  VAL 47  47  47  VAL VAL A . n 
A 1 48  LEU 48  48  48  LEU LEU A . n 
A 1 49  MET 49  49  49  MET MET A . n 
A 1 50  ALA 50  50  50  ALA ALA A . n 
A 1 51  LYS 51  51  51  LYS LYS A . n 
A 1 52  ASP 52  52  52  ASP ASP A . n 
A 1 53  ASP 53  53  53  ASP ASP A . n 
A 1 54  ILE 54  54  54  ILE ILE A . n 
A 1 55  LEU 55  55  55  LEU LEU A . n 
A 1 56  ALA 56  56  56  ALA ALA A . n 
A 1 57  GLY 57  57  57  GLY GLY A . n 
A 1 58  GLN 58  58  58  GLN GLN A . n 
A 1 59  SER 59  59  59  SER SER A . n 
A 1 60  ALA 60  60  60  ALA ALA A . n 
A 1 61  TRP 61  61  61  TRP TRP A . n 
A 1 62  GLN 62  62  62  GLN GLN A . n 
A 1 63  THR 63  63  63  THR THR A . n 
A 1 64  THR 64  64  64  THR THR A . n 
A 1 65  GLY 65  65  65  GLY GLY A . n 
A 1 66  GLY 66  66  66  GLY GLY A . n 
A 1 67  MET 67  67  67  MET MET A . n 
A 1 68  GLU 68  68  68  GLU GLU A . n 
A 1 69  VAL 69  69  69  VAL VAL A . n 
A 1 70  GLY 70  70  70  GLY GLY A . n 
A 1 71  SER 71  71  71  SER SER A . n 
A 1 72  VAL 72  72  72  VAL VAL A . n 
A 1 73  LEU 73  73  73  LEU LEU A . n 
A 1 74  GLY 74  74  74  GLY GLY A . n 
A 1 75  HIS 75  75  75  HIS HIS A . n 
A 1 76  GLY 76  76  76  GLY GLY A . n 
A 1 77  ALA 77  77  77  ALA ALA A . n 
A 1 78  TYR 78  78  78  TYR TYR A . n 
A 1 79  GLN 79  79  79  GLN GLN A . n 
A 1 80  ALA 80  80  80  ALA ALA A . n 
A 1 81  PRO 81  81  81  PRO PRO A . n 
A 1 82  ASP 82  82  82  ASP ASP A . n 
A 1 83  TRP 83  83  83  TRP TRP A . n 
A 1 84  THR 84  84  84  THR THR A . n 
A 1 85  ALA 85  85  85  ALA ALA A . n 
A 1 86  ASP 86  86  86  ASP ASP A . n 
A 1 87  TRP 87  87  87  TRP TRP A . n 
A 1 88  LEU 88  88  88  LEU LEU A . n 
A 1 89  HIS 89  89  89  HIS HIS A . n 
A 1 90  ARG 90  90  90  ARG ARG A . n 
A 1 91  GLU 91  91  91  GLU GLU A . n 
A 1 92  LEU 92  92  92  LEU LEU A . n 
A 1 93  SER 93  93  93  SER SER A . n 
A 1 94  ALA 94  94  94  ALA ALA A . n 
A 1 95  TRP 95  95  95  TRP TRP A . n 
A 1 96  LEU 96  96  96  LEU LEU A . n 
A 1 97  ASP 97  97  97  ASP ASP A . n 
A 1 98  LEU 98  98  98  LEU LEU A . n 
A 1 99  THR 99  99  99  THR THR A . n 
A 1 100 ALA 100 100 100 ALA ALA A . n 
A 1 101 GLN 101 101 101 GLN GLN A . n 
A 1 102 GLN 102 102 102 GLN GLN A . n 
A 1 103 THR 103 103 103 THR THR A . n 
A 1 104 TYR 104 104 104 TYR TYR A . n 
A 1 105 GLY 105 105 105 GLY GLY A . n 
A 1 106 LYS 106 106 106 LYS LYS A . n 
A 1 107 LYS 107 107 107 LYS LYS A . n 
A 1 108 PHE 108 108 108 PHE PHE A . n 
A 1 109 ASP 109 109 109 ASP ASP A . n 
A 1 110 GLU 110 110 110 GLU GLU A . n 
A 1 111 VAL 111 111 111 VAL VAL A . n 
A 1 112 SER 112 112 112 SER SER A . n 
A 1 113 PRO 113 113 113 PRO PRO A . n 
A 1 114 GLU 114 114 114 GLU GLU A . n 
A 1 115 GLU 115 115 115 GLU GLU A . n 
A 1 116 GLN 116 116 116 GLN GLN A . n 
A 1 117 ALA 117 117 117 ALA ALA A . n 
A 1 118 VAL 118 118 118 VAL VAL A . n 
A 1 119 LEU 119 119 119 LEU LEU A . n 
A 1 120 LYS 120 120 120 LYS LYS A . n 
A 1 121 THR 121 121 121 THR THR A . n 
A 1 122 ARG 122 122 122 ARG ARG A . n 
A 1 123 LEU 123 123 123 LEU LEU A . n 
A 1 124 ALA 124 124 124 ALA ALA A . n 
A 1 125 ASP 125 125 125 ASP ASP A . n 
A 1 126 GLU 126 126 126 GLU GLU A . n 
A 1 127 TYR 127 127 127 TYR TYR A . n 
A 1 128 ARG 128 128 128 ARG ARG A . n 
A 1 129 ASN 129 129 129 ASN ASN A . n 
A 1 130 GLN 130 130 130 GLN GLN A . n 
A 1 131 SER 131 131 131 SER SER A . n 
A 1 132 ARG 132 132 132 ARG ARG A . n 
A 1 133 ILE 133 133 133 ILE ILE A . n 
A 1 134 LYS 134 134 134 LYS LYS A . n 
A 1 135 GLU 135 135 135 GLU GLU A . n 
A 1 136 ASP 136 136 136 ASP ASP A . n 
A 1 137 GLY 137 137 137 GLY GLY A . n 
A 1 138 SER 138 138 138 SER SER A . n 
A 1 139 VAL 139 139 139 VAL VAL A . n 
A 1 140 VAL 140 140 140 VAL VAL A . n 
A 1 141 ILE 141 141 141 ILE ILE A . n 
A 1 142 SER 142 142 142 SER SER A . n 
A 1 143 ASP 143 143 143 ASP ASP A . n 
A 1 144 THR 144 144 144 THR THR A . n 
A 1 145 ARG 145 145 145 ARG ARG A . n 
A 1 146 VAL 146 146 146 VAL VAL A . n 
A 1 147 LYS 147 147 147 LYS LYS A . n 
A 1 148 ALA 148 148 148 ALA ALA A . n 
A 1 149 ILE 149 149 149 ILE ILE A . n 
A 1 150 GLU 150 150 150 GLU GLU A . n 
A 1 151 SER 151 151 151 SER SER A . n 
A 1 152 ILE 152 152 152 ILE ILE A . n 
A 1 153 LEU 153 153 153 LEU LEU A . n 
A 1 154 PRO 154 154 154 PRO PRO A . n 
A 1 155 TYR 155 155 155 TYR TYR A . n 
A 1 156 TYR 156 156 156 TYR TYR A . n 
A 1 157 HIS 157 157 157 HIS HIS A . n 
A 1 158 GLY 158 158 158 GLY GLY A . n 
A 1 159 VAL 159 159 159 VAL VAL A . n 
A 1 160 TYR 160 160 160 TYR TYR A . n 
A 1 161 GLY 161 161 161 GLY GLY A . n 
A 1 162 ASP 162 162 162 ASP ASP A . n 
A 1 163 ASP 163 163 163 ASP ASP A . n 
A 1 164 PRO 164 164 164 PRO PRO A . n 
A 1 165 ALA 165 165 165 ALA ALA A . n 
A 1 166 LEU 166 166 166 LEU LEU A . n 
A 1 167 GLN 167 167 167 GLN GLN A . n 
A 1 168 THR 168 168 168 THR THR A . n 
A 1 169 THR 169 169 169 THR THR A . n 
A 1 170 ARG 170 170 170 ARG ARG A . n 
A 1 171 GLU 171 171 171 GLU GLU A . n 
A 1 172 HIS 172 172 172 HIS HIS A . n 
A 1 173 PHE 173 173 173 PHE PHE A . n 
A 1 174 ALA 174 174 174 ALA ALA A . n 
A 1 175 MET 175 175 175 MET MET A . n 
A 1 176 LYS 176 176 176 LYS LYS A . n 
A 1 177 ASN 177 177 177 ASN ASN A . n 
A 1 178 ASN 178 178 178 ASN ASN A . n 
A 1 179 THR 179 179 179 THR THR A . n 
A 1 180 LEU 180 180 180 LEU LEU A . n 
A 1 181 PRO 181 181 181 PRO PRO A . n 
A 1 182 SER 182 182 182 SER SER A . n 
A 1 183 GLN 183 183 183 GLN GLN A . n 
A 1 184 GLU 184 184 184 GLU GLU A . n 
A 1 185 ALA 185 185 185 ALA ALA A . n 
A 1 186 ARG 186 186 186 ARG ARG A . n 
A 1 187 GLU 187 187 187 GLU GLU A . n 
A 1 188 LYS 188 188 188 LYS LYS A . n 
A 1 189 LEU 189 189 189 LEU LEU A . n 
A 1 190 PHE 190 190 190 PHE PHE A . n 
A 1 191 ASP 191 191 191 ASP ASP A . n 
A 1 192 PHE 192 192 192 PHE PHE A . n 
A 1 193 PHE 193 193 193 PHE PHE A . n 
A 1 194 PHE 194 194 194 PHE PHE A . n 
A 1 195 TRP 195 195 195 TRP TRP A . n 
A 1 196 THR 196 196 196 THR THR A . n 
A 1 197 SER 197 197 197 SER SER A . n 
A 1 198 TRP 198 198 198 TRP TRP A . n 
A 1 199 SER 199 199 199 SER SER A . n 
A 1 200 ALA 200 200 200 ALA ALA A . n 
A 1 201 SER 201 201 201 SER SER A . n 
A 1 202 THR 202 202 202 THR THR A . n 
A 1 203 ASN 203 203 203 ASN ASN A . n 
A 1 204 ARG 204 204 204 ARG ARG A . n 
A 1 205 PRO 205 205 205 PRO PRO A . n 
A 1 206 ASP 206 206 206 ASP ASP A . n 
A 1 207 GLU 207 207 207 GLU GLU A . n 
A 1 208 THR 208 208 208 THR THR A . n 
A 1 209 PHE 209 209 209 PHE PHE A . n 
A 1 210 THR 210 210 210 THR THR A . n 
A 1 211 TYR 211 211 211 TYR TYR A . n 
A 1 212 THR 212 212 212 THR THR A . n 
A 1 213 ASN 213 213 213 ASN ASN A . n 
A 1 214 ASN 214 214 214 ASN ASN A . n 
A 1 215 TRP 215 215 215 TRP TRP A . n 
A 1 216 PRO 216 216 216 PRO PRO A . n 
A 1 217 HIS 217 217 217 HIS HIS A . n 
A 1 218 GLU 218 218 218 GLU GLU A . n 
A 1 219 PRO 219 219 219 PRO PRO A . n 
A 1 220 LEU 220 220 220 LEU LEU A . n 
A 1 221 ILE 221 221 221 ILE ILE A . n 
A 1 222 ASN 222 222 222 ASN ASN A . n 
A 1 223 ASN 223 223 223 ASN ASN A . n 
A 1 224 VAL 224 224 224 VAL VAL A . n 
A 1 225 PRO 225 225 225 PRO PRO A . n 
A 1 226 THR 226 226 226 THR THR A . n 
A 1 227 THR 227 227 227 THR THR A . n 
A 1 228 GLU 228 228 228 GLU GLU A . n 
A 1 229 ASN 229 229 229 ASN ASN A . n 
A 1 230 TYR 230 230 230 TYR TYR A . n 
A 1 231 MET 231 231 231 MET MET A . n 
A 1 232 TRP 232 232 232 TRP TRP A . n 
A 1 233 SER 233 233 233 SER SER A . n 
A 1 234 PHE 234 234 234 PHE PHE A . n 
A 1 235 THR 235 235 235 THR THR A . n 
A 1 236 SER 236 236 236 SER SER A . n 
A 1 237 VAL 237 237 237 VAL VAL A . n 
A 1 238 VAL 238 238 238 VAL VAL A . n 
A 1 239 LEU 239 239 239 LEU LEU A . n 
A 1 240 LEU 240 240 240 LEU LEU A . n 
A 1 241 LEU 241 241 241 LEU LEU A . n 
A 1 242 MET 242 242 242 MET MET A . n 
A 1 243 GLY 243 243 243 GLY GLY A . n 
A 1 244 ILE 244 244 244 ILE ILE A . n 
A 1 245 GLY 245 245 245 GLY GLY A . n 
A 1 246 LEU 246 246 246 LEU LEU A . n 
A 1 247 LEU 247 247 247 LEU LEU A . n 
A 1 248 MET 248 248 248 MET MET A . n 
A 1 249 TRP 249 249 249 TRP TRP A . n 
A 1 250 GLY 250 250 250 GLY GLY A . n 
A 1 251 TYR 251 251 251 TYR TYR A . n 
A 1 252 SER 252 252 252 SER SER A . n 
A 1 253 PHE 253 253 253 PHE PHE A . n 
A 1 254 LEU 254 254 254 LEU LEU A . n 
A 1 255 THR 255 255 255 THR THR A . n 
A 1 256 LYS 256 256 256 LYS LYS A . n 
A 1 257 HIS 257 257 257 HIS HIS A . n 
A 1 258 GLU 258 258 258 GLU GLU A . n 
A 1 259 GLU 259 259 259 GLU GLU A . n 
A 1 260 VAL 260 260 260 VAL VAL A . n 
A 1 261 GLU 261 261 261 GLU GLU A . n 
A 1 262 VAL 262 262 262 VAL VAL A . n 
A 1 263 PRO 263 263 263 PRO PRO A . n 
A 1 264 THR 264 264 264 THR THR A . n 
A 1 265 GLU 265 265 265 GLU GLU A . n 
A 1 266 ASP 266 266 266 ASP ASP A . n 
A 1 267 PRO 267 267 267 PRO PRO A . n 
A 1 268 ILE 268 268 ?   ?   ?   A . n 
A 1 269 SER 269 269 269 SER SER A . n 
A 1 270 LYS 270 270 270 LYS LYS A . n 
A 1 271 VAL 271 271 271 VAL VAL A . n 
A 1 272 GLN 272 272 272 GLN GLN A . n 
A 1 273 LEU 273 273 273 LEU LEU A . n 
A 1 274 THR 274 274 274 THR THR A . n 
A 1 275 PRO 275 275 275 PRO PRO A . n 
A 1 276 SER 276 276 276 SER SER A . n 
A 1 277 GLN 277 277 277 GLN GLN A . n 
A 1 278 LYS 278 278 278 LYS LYS A . n 
A 1 279 ALA 279 279 279 ALA ALA A . n 
A 1 280 LEU 280 280 280 LEU LEU A . n 
A 1 281 GLY 281 281 281 GLY GLY A . n 
A 1 282 LYS 282 282 282 LYS LYS A . n 
A 1 283 TYR 283 283 283 TYR TYR A . n 
A 1 284 VAL 284 284 284 VAL VAL A . n 
A 1 285 PHE 285 285 285 PHE PHE A . n 
A 1 286 LEU 286 286 286 LEU LEU A . n 
A 1 287 THR 287 287 287 THR THR A . n 
A 1 288 VAL 288 288 288 VAL VAL A . n 
A 1 289 ALA 289 289 289 ALA ALA A . n 
A 1 290 LEU 290 290 290 LEU LEU A . n 
A 1 291 PHE 291 291 291 PHE PHE A . n 
A 1 292 VAL 292 292 292 VAL VAL A . n 
A 1 293 VAL 293 293 293 VAL VAL A . n 
A 1 294 GLN 294 294 294 GLN GLN A . n 
A 1 295 VAL 295 295 295 VAL VAL A . n 
A 1 296 LEU 296 296 296 LEU LEU A . n 
A 1 297 LEU 297 297 297 LEU LEU A . n 
A 1 298 GLY 298 298 298 GLY GLY A . n 
A 1 299 GLY 299 299 299 GLY GLY A . n 
A 1 300 LEU 300 300 300 LEU LEU A . n 
A 1 301 THR 301 301 301 THR THR A . n 
A 1 302 ALA 302 302 302 ALA ALA A . n 
A 1 303 HIS 303 303 303 HIS HIS A . n 
A 1 304 TYR 304 304 304 TYR TYR A . n 
A 1 305 THR 305 305 305 THR THR A . n 
A 1 306 VAL 306 306 306 VAL VAL A . n 
A 1 307 GLU 307 307 307 GLU GLU A . n 
A 1 308 GLY 308 308 308 GLY GLY A . n 
A 1 309 GLN 309 309 309 GLN GLN A . n 
A 1 310 GLY 310 310 310 GLY GLY A . n 
A 1 311 PHE 311 311 311 PHE PHE A . n 
A 1 312 TYR 312 312 312 TYR TYR A . n 
A 1 313 GLY 313 313 313 GLY ALA A . n 
A 1 314 ILE 314 314 314 ILE ALA A . n 
A 1 315 ASP 315 315 ?   ?   ?   A . n 
A 1 316 GLU 316 316 ?   ?   ?   A . n 
A 1 317 ALA 317 317 ?   ?   ?   A . n 
A 1 318 LEU 318 318 318 LEU LEU A . n 
A 1 319 GLY 319 319 319 GLY GLY A . n 
A 1 320 PHE 320 320 320 PHE PHE A . n 
A 1 321 GLU 321 321 321 GLU GLU A . n 
A 1 322 MET 322 322 322 MET MET A . n 
A 1 323 SER 323 323 323 SER SER A . n 
A 1 324 ASP 324 324 324 ASP ASP A . n 
A 1 325 TRP 325 325 325 TRP TRP A . n 
A 1 326 PHE 326 326 326 PHE PHE A . n 
A 1 327 PRO 327 327 327 PRO PRO A . n 
A 1 328 TYR 328 328 328 TYR TYR A . n 
A 1 329 ALA 329 329 329 ALA ALA A . n 
A 1 330 LEU 330 330 330 LEU LEU A . n 
A 1 331 THR 331 331 331 THR THR A . n 
A 1 332 ARG 332 332 332 ARG ARG A . n 
A 1 333 THR 333 333 333 THR THR A . n 
A 1 334 TRP 334 334 334 TRP TRP A . n 
A 1 335 HIS 335 335 335 HIS HIS A . n 
A 1 336 ILE 336 336 336 ILE ILE A . n 
A 1 337 GLN 337 337 337 GLN GLN A . n 
A 1 338 SER 338 338 338 SER SER A . n 
A 1 339 ALA 339 339 339 ALA ALA A . n 
A 1 340 ILE 340 340 340 ILE ILE A . n 
A 1 341 PHE 341 341 341 PHE PHE A . n 
A 1 342 TRP 342 342 342 TRP TRP A . n 
A 1 343 ILE 343 343 343 ILE ILE A . n 
A 1 344 ALA 344 344 344 ALA ALA A . n 
A 1 345 THR 345 345 345 THR THR A . n 
A 1 346 GLY 346 346 346 GLY GLY A . n 
A 1 347 PHE 347 347 347 PHE PHE A . n 
A 1 348 LEU 348 348 348 LEU LEU A . n 
A 1 349 THR 349 349 349 THR THR A . n 
A 1 350 ALA 350 350 350 ALA ALA A . n 
A 1 351 GLY 351 351 351 GLY GLY A . n 
A 1 352 LEU 352 352 352 LEU LEU A . n 
A 1 353 PHE 353 353 353 PHE PHE A . n 
A 1 354 LEU 354 354 354 LEU LEU A . n 
A 1 355 ALA 355 355 355 ALA ALA A . n 
A 1 356 PRO 356 356 356 PRO PRO A . n 
A 1 357 ILE 357 357 357 ILE ILE A . n 
A 1 358 VAL 358 358 358 VAL VAL A . n 
A 1 359 ASN 359 359 359 ASN ASN A . n 
A 1 360 GLY 360 360 360 GLY GLY A . n 
A 1 361 GLY 361 361 361 GLY GLY A . n 
A 1 362 LYS 362 362 362 LYS LYS A . n 
A 1 363 ASP 363 363 363 ASP ASP A . n 
A 1 364 PRO 364 364 364 PRO PRO A . n 
A 1 365 LYS 365 365 365 LYS LYS A . n 
A 1 366 PHE 366 366 366 PHE PHE A . n 
A 1 367 GLN 367 367 367 GLN GLN A . n 
A 1 368 ARG 368 368 368 ARG ARG A . n 
A 1 369 ALA 369 369 369 ALA ALA A . n 
A 1 370 GLY 370 370 370 GLY GLY A . n 
A 1 371 VAL 371 371 371 VAL VAL A . n 
A 1 372 ASN 372 372 372 ASN ASN A . n 
A 1 373 PHE 373 373 373 PHE PHE A . n 
A 1 374 LEU 374 374 374 LEU LEU A . n 
A 1 375 TYR 375 375 375 TYR TYR A . n 
A 1 376 ILE 376 376 376 ILE ILE A . n 
A 1 377 ALA 377 377 377 ALA ALA A . n 
A 1 378 LEU 378 378 378 LEU LEU A . n 
A 1 379 PHE 379 379 379 PHE PHE A . n 
A 1 380 ILE 380 380 380 ILE ILE A . n 
A 1 381 VAL 381 381 381 VAL VAL A . n 
A 1 382 VAL 382 382 382 VAL VAL A . n 
A 1 383 GLY 383 383 383 GLY GLY A . n 
A 1 384 GLY 384 384 384 GLY GLY A . n 
A 1 385 SER 385 385 385 SER SER A . n 
A 1 386 TYR 386 386 386 TYR TYR A . n 
A 1 387 ALA 387 387 387 ALA ALA A . n 
A 1 388 GLY 388 388 388 GLY GLY A . n 
A 1 389 ASN 389 389 389 ASN ASN A . n 
A 1 390 PHE 390 390 390 PHE PHE A . n 
A 1 391 PHE 391 391 391 PHE PHE A . n 
A 1 392 ALA 392 392 392 ALA ALA A . n 
A 1 393 LEU 393 393 393 LEU LEU A . n 
A 1 394 THR 394 394 394 THR THR A . n 
A 1 395 HIS 395 395 395 HIS HIS A . n 
A 1 396 ILE 396 396 396 ILE ILE A . n 
A 1 397 LEU 397 397 397 LEU LEU A . n 
A 1 398 PRO 398 398 398 PRO PRO A . n 
A 1 399 PRO 399 399 399 PRO PRO A . n 
A 1 400 GLU 400 400 400 GLU GLU A . n 
A 1 401 PHE 401 401 401 PHE PHE A . n 
A 1 402 ASN 402 402 402 ASN ASN A . n 
A 1 403 PHE 403 403 403 PHE PHE A . n 
A 1 404 TRP 404 404 404 TRP TRP A . n 
A 1 405 PHE 405 405 405 PHE PHE A . n 
A 1 406 GLY 406 406 406 GLY GLY A . n 
A 1 407 HIS 407 407 407 HIS HIS A . n 
A 1 408 GLN 408 408 408 GLN GLN A . n 
A 1 409 GLY 409 409 409 GLY GLY A . n 
A 1 410 TYR 410 410 410 TYR TYR A . n 
A 1 411 GLU 411 411 411 GLU GLU A . n 
A 1 412 TYR 412 412 412 TYR TYR A . n 
A 1 413 LEU 413 413 413 LEU LEU A . n 
A 1 414 ASP 414 414 414 ASP ASP A . n 
A 1 415 LEU 415 415 415 LEU LEU A . n 
A 1 416 GLY 416 416 416 GLY GLY A . n 
A 1 417 ARG 417 417 417 ARG ARG A . n 
A 1 418 PHE 418 418 418 PHE PHE A . n 
A 1 419 TRP 419 419 419 TRP TRP A . n 
A 1 420 GLN 420 420 420 GLN GLN A . n 
A 1 421 LEU 421 421 421 LEU LEU A . n 
A 1 422 LEU 422 422 422 LEU LEU A . n 
A 1 423 LEU 423 423 423 LEU LEU A . n 
A 1 424 MET 424 424 424 MET MET A . n 
A 1 425 VAL 425 425 425 VAL VAL A . n 
A 1 426 GLY 426 426 426 GLY GLY A . n 
A 1 427 LEU 427 427 427 LEU LEU A . n 
A 1 428 LEU 428 428 428 LEU LEU A . n 
A 1 429 LEU 429 429 429 LEU LEU A . n 
A 1 430 TRP 430 430 430 TRP TRP A . n 
A 1 431 LEU 431 431 431 LEU LEU A . n 
A 1 432 PHE 432 432 432 PHE PHE A . n 
A 1 433 LEU 433 433 433 LEU LEU A . n 
A 1 434 MET 434 434 434 MET MET A . n 
A 1 435 LEU 435 435 435 LEU LEU A . n 
A 1 436 ARG 436 436 436 ARG ARG A . n 
A 1 437 CYS 437 437 437 CYS CYS A . n 
A 1 438 THR 438 438 438 THR THR A . n 
A 1 439 VAL 439 439 439 VAL VAL A . n 
A 1 440 SER 440 440 440 SER SER A . n 
A 1 441 ALA 441 441 441 ALA ALA A . n 
A 1 442 PHE 442 442 442 PHE PHE A . n 
A 1 443 LYS 443 443 443 LYS LYS A . n 
A 1 444 GLU 444 444 444 GLU GLU A . n 
A 1 445 LYS 445 445 445 LYS LYS A . n 
A 1 446 GLY 446 446 446 GLY GLY A . n 
A 1 447 VAL 447 447 447 VAL VAL A . n 
A 1 448 ASP 448 448 448 ASP ASP A . n 
A 1 449 LYS 449 449 449 LYS LYS A . n 
A 1 450 ASN 450 450 450 ASN ASN A . n 
A 1 451 LEU 451 451 451 LEU LEU A . n 
A 1 452 LEU 452 452 452 LEU LEU A . n 
A 1 453 ALA 453 453 453 ALA ALA A . n 
A 1 454 ILE 454 454 454 ILE ILE A . n 
A 1 455 PHE 455 455 455 PHE PHE A . n 
A 1 456 VAL 456 456 456 VAL VAL A . n 
A 1 457 ALA 457 457 457 ALA ALA A . n 
A 1 458 SER 458 458 458 SER SER A . n 
A 1 459 MET 459 459 459 MET MET A . n 
A 1 460 VAL 460 460 460 VAL VAL A . n 
A 1 461 GLY 461 461 461 GLY GLY A . n 
A 1 462 VAL 462 462 462 VAL VAL A . n 
A 1 463 GLY 463 463 463 GLY GLY A . n 
A 1 464 VAL 464 464 464 VAL VAL A . n 
A 1 465 PHE 465 465 465 PHE PHE A . n 
A 1 466 TYR 466 466 466 TYR TYR A . n 
A 1 467 ALA 467 467 467 ALA ALA A . n 
A 1 468 PRO 468 468 468 PRO PRO A . n 
A 1 469 GLY 469 469 469 GLY GLY A . n 
A 1 470 LEU 470 470 470 LEU LEU A . n 
A 1 471 PHE 471 471 471 PHE PHE A . n 
A 1 472 TYR 472 472 472 TYR TYR A . n 
A 1 473 GLY 473 473 473 GLY GLY A . n 
A 1 474 GLU 474 474 474 GLU GLU A . n 
A 1 475 LYS 475 475 475 LYS LYS A . n 
A 1 476 SER 476 476 476 SER SER A . n 
A 1 477 PRO 477 477 477 PRO PRO A . n 
A 1 478 ILE 478 478 478 ILE ILE A . n 
A 1 479 ALA 479 479 479 ALA ALA A . n 
A 1 480 VAL 480 480 480 VAL VAL A . n 
A 1 481 MET 481 481 481 MET MET A . n 
A 1 482 GLU 482 482 482 GLU GLU A . n 
A 1 483 TYR 483 483 483 TYR TYR A . n 
A 1 484 TRP 484 484 484 TRP TRP A . n 
A 1 485 ARG 485 485 485 ARG ARG A . n 
A 1 486 TRP 486 486 486 TRP TRP A . n 
A 1 487 TRP 487 487 487 TRP TRP A . n 
A 1 488 VAL 488 488 488 VAL VAL A . n 
A 1 489 VAL 489 489 489 VAL VAL A . n 
A 1 490 HIS 490 490 490 HIS HIS A . n 
A 1 491 LEU 491 491 491 LEU LEU A . n 
A 1 492 TRP 492 492 492 TRP TRP A . n 
A 1 493 VAL 493 493 493 VAL VAL A . n 
A 1 494 GLU 494 494 494 GLU GLU A . n 
A 1 495 GLY 495 495 495 GLY GLY A . n 
A 1 496 PHE 496 496 496 PHE PHE A . n 
A 1 497 PHE 497 497 497 PHE PHE A . n 
A 1 498 GLU 498 498 498 GLU GLU A . n 
A 1 499 VAL 499 499 499 VAL VAL A . n 
A 1 500 PHE 500 500 500 PHE PHE A . n 
A 1 501 ALA 501 501 501 ALA ALA A . n 
A 1 502 THR 502 502 502 THR THR A . n 
A 1 503 ALA 503 503 503 ALA ALA A . n 
A 1 504 ALA 504 504 504 ALA ALA A . n 
A 1 505 PHE 505 505 505 PHE PHE A . n 
A 1 506 ALA 506 506 506 ALA ALA A . n 
A 1 507 PHE 507 507 507 PHE PHE A . n 
A 1 508 VAL 508 508 508 VAL VAL A . n 
A 1 509 PHE 509 509 509 PHE PHE A . n 
A 1 510 TYR 510 510 510 TYR TYR A . n 
A 1 511 ASN 511 511 511 ASN ASN A . n 
A 1 512 MET 512 512 512 MET MET A . n 
A 1 513 GLY 513 513 513 GLY GLY A . n 
A 1 514 PHE 514 514 514 PHE PHE A . n 
A 1 515 VAL 515 515 515 VAL VAL A . n 
A 1 516 ARG 516 516 516 ARG ARG A . n 
A 1 517 ARG 517 517 517 ARG ARG A . n 
A 1 518 SER 518 518 518 SER SER A . n 
A 1 519 THR 519 519 519 THR THR A . n 
A 1 520 ALA 520 520 520 ALA ALA A . n 
A 1 521 THR 521 521 521 THR THR A . n 
A 1 522 ALA 522 522 522 ALA ALA A . n 
A 1 523 SER 523 523 523 SER SER A . n 
A 1 524 THR 524 524 524 THR THR A . n 
A 1 525 LEU 525 525 525 LEU LEU A . n 
A 1 526 ALA 526 526 526 ALA ALA A . n 
A 1 527 ALA 527 527 527 ALA ALA A . n 
A 1 528 ALA 528 528 528 ALA ALA A . n 
A 1 529 ALA 529 529 529 ALA ALA A . n 
A 1 530 ILE 530 530 530 ILE ILE A . n 
A 1 531 PHE 531 531 531 PHE PHE A . n 
A 1 532 MET 532 532 532 MET MET A . n 
A 1 533 LEU 533 533 533 LEU LEU A . n 
A 1 534 GLY 534 534 534 GLY GLY A . n 
A 1 535 GLY 535 535 535 GLY GLY A . n 
A 1 536 VAL 536 536 536 VAL VAL A . n 
A 1 537 PRO 537 537 537 PRO PRO A . n 
A 1 538 GLY 538 538 538 GLY GLY A . n 
A 1 539 THR 539 539 539 THR THR A . n 
A 1 540 LEU 540 540 540 LEU LEU A . n 
A 1 541 HIS 541 541 541 HIS HIS A . n 
A 1 542 HIS 542 542 542 HIS HIS A . n 
A 1 543 LEU 543 543 543 LEU LEU A . n 
A 1 544 TYR 544 544 544 TYR TYR A . n 
A 1 545 PHE 545 545 545 PHE PHE A . n 
A 1 546 SER 546 546 546 SER SER A . n 
A 1 547 GLY 547 547 547 GLY GLY A . n 
A 1 548 SER 548 548 548 SER SER A . n 
A 1 549 THR 549 549 549 THR THR A . n 
A 1 550 SER 550 550 550 SER SER A . n 
A 1 551 ALA 551 551 551 ALA ALA A . n 
A 1 552 SER 552 552 552 SER SER A . n 
A 1 553 MET 553 553 553 MET MET A . n 
A 1 554 ALA 554 554 554 ALA ALA A . n 
A 1 555 ILE 555 555 555 ILE ILE A . n 
A 1 556 GLY 556 556 556 GLY GLY A . n 
A 1 557 ALA 557 557 557 ALA ALA A . n 
A 1 558 CYS 558 558 558 CYS CYS A . n 
A 1 559 PHE 559 559 559 PHE PHE A . n 
A 1 560 SER 560 560 560 SER SER A . n 
A 1 561 ALA 561 561 561 ALA ALA A . n 
A 1 562 LEU 562 562 562 LEU LEU A . n 
A 1 563 GLU 563 563 563 GLU GLU A . n 
A 1 564 VAL 564 564 564 VAL VAL A . n 
A 1 565 VAL 565 565 565 VAL VAL A . n 
A 1 566 PRO 566 566 566 PRO PRO A . n 
A 1 567 LEU 567 567 567 LEU LEU A . n 
A 1 568 VAL 568 568 568 VAL VAL A . n 
A 1 569 LEU 569 569 569 LEU LEU A . n 
A 1 570 LEU 570 570 570 LEU LEU A . n 
A 1 571 GLY 571 571 571 GLY GLY A . n 
A 1 572 ARG 572 572 572 ARG ARG A . n 
A 1 573 GLU 573 573 573 GLU GLU A . n 
A 1 574 ALA 574 574 574 ALA ALA A . n 
A 1 575 TYR 575 575 575 TYR TYR A . n 
A 1 576 GLU 576 576 576 GLU GLU A . n 
A 1 577 HIS 577 577 577 HIS HIS A . n 
A 1 578 TRP 578 578 578 TRP TRP A . n 
A 1 579 SER 579 579 579 SER SER A . n 
A 1 580 TYR 580 580 580 TYR TYR A . n 
A 1 581 GLN 581 581 581 GLN GLN A . n 
A 1 582 HIS 582 582 582 HIS HIS A . n 
A 1 583 LEU 583 583 583 LEU LEU A . n 
A 1 584 SER 584 584 584 SER SER A . n 
A 1 585 GLU 585 585 585 GLU GLU A . n 
A 1 586 TRP 586 586 586 TRP TRP A . n 
A 1 587 ALA 587 587 587 ALA ALA A . n 
A 1 588 LYS 588 588 588 LYS LYS A . n 
A 1 589 ARG 589 589 589 ARG ARG A . n 
A 1 590 LEU 590 590 590 LEU LEU A . n 
A 1 591 ARG 591 591 591 ARG ARG A . n 
A 1 592 TRP 592 592 592 TRP TRP A . n 
A 1 593 PRO 593 593 593 PRO PRO A . n 
A 1 594 LEU 594 594 594 LEU LEU A . n 
A 1 595 MET 595 595 595 MET MET A . n 
A 1 596 CYS 596 596 596 CYS CYS A . n 
A 1 597 PHE 597 597 597 PHE PHE A . n 
A 1 598 VAL 598 598 598 VAL VAL A . n 
A 1 599 ALA 599 599 599 ALA ALA A . n 
A 1 600 VAL 600 600 600 VAL VAL A . n 
A 1 601 ALA 601 601 601 ALA ALA A . n 
A 1 602 PHE 602 602 602 PHE PHE A . n 
A 1 603 TRP 603 603 603 TRP TRP A . n 
A 1 604 ASN 604 604 604 ASN ASN A . n 
A 1 605 MET 605 605 605 MET MET A . n 
A 1 606 ILE 606 606 606 ILE ILE A . n 
A 1 607 GLY 607 607 607 GLY GLY A . n 
A 1 608 ALA 608 608 608 ALA ALA A . n 
A 1 609 GLY 609 609 609 GLY GLY A . n 
A 1 610 VAL 610 610 610 VAL VAL A . n 
A 1 611 PHE 611 611 611 PHE PHE A . n 
A 1 612 GLY 612 612 612 GLY GLY A . n 
A 1 613 PHE 613 613 613 PHE PHE A . n 
A 1 614 LEU 614 614 614 LEU LEU A . n 
A 1 615 ILE 615 615 615 ILE ILE A . n 
A 1 616 ASN 616 616 616 ASN ASN A . n 
A 1 617 PRO 617 617 617 PRO PRO A . n 
A 1 618 PRO 618 618 618 PRO PRO A . n 
A 1 619 ILE 619 619 619 ILE ILE A . n 
A 1 620 SER 620 620 620 SER SER A . n 
A 1 621 LEU 621 621 621 LEU LEU A . n 
A 1 622 PHE 622 622 622 PHE PHE A . n 
A 1 623 TYR 623 623 623 TYR TYR A . n 
A 1 624 ILE 624 624 624 ILE ILE A . n 
A 1 625 GLN 625 625 625 GLN GLN A . n 
A 1 626 GLY 626 626 626 GLY GLY A . n 
A 1 627 LEU 627 627 627 LEU LEU A . n 
A 1 628 ASN 628 628 628 ASN ASN A . n 
A 1 629 THR 629 629 629 THR THR A . n 
A 1 630 SER 630 630 630 SER SER A . n 
A 1 631 ALA 631 631 631 ALA ALA A . n 
A 1 632 VAL 632 632 632 VAL VAL A . n 
A 1 633 HIS 633 633 633 HIS HIS A . n 
A 1 634 ALA 634 634 634 ALA ALA A . n 
A 1 635 HIS 635 635 635 HIS HIS A . n 
A 1 636 ALA 636 636 636 ALA ALA A . n 
A 1 637 ALA 637 637 637 ALA ALA A . n 
A 1 638 LEU 638 638 638 LEU LEU A . n 
A 1 639 PHE 639 639 639 PHE PHE A . n 
A 1 640 GLY 640 640 640 GLY GLY A . n 
A 1 641 VAL 641 641 641 VAL VAL A . n 
A 1 642 TYR 642 642 642 TYR TYR A . n 
A 1 643 GLY 643 643 643 GLY GLY A . n 
A 1 644 PHE 644 644 644 PHE PHE A . n 
A 1 645 LEU 645 645 645 LEU LEU A . n 
A 1 646 ALA 646 646 646 ALA ALA A . n 
A 1 647 LEU 647 647 647 LEU LEU A . n 
A 1 648 GLY 648 648 648 GLY GLY A . n 
A 1 649 PHE 649 649 649 PHE PHE A . n 
A 1 650 VAL 650 650 650 VAL VAL A . n 
A 1 651 LEU 651 651 651 LEU LEU A . n 
A 1 652 LEU 652 652 652 LEU LEU A . n 
A 1 653 VAL 653 653 653 VAL VAL A . n 
A 1 654 ALA 654 654 654 ALA ALA A . n 
A 1 655 ARG 655 655 655 ARG ARG A . n 
A 1 656 TYR 656 656 656 TYR TYR A . n 
A 1 657 LEU 657 657 657 LEU LEU A . n 
A 1 658 LYS 658 658 658 LYS LYS A . n 
A 1 659 PRO 659 659 659 PRO PRO A . n 
A 1 660 ASN 660 660 660 ASN ASN A . n 
A 1 661 VAL 661 661 661 VAL VAL A . n 
A 1 662 GLN 662 662 662 GLN GLN A . n 
A 1 663 PHE 663 663 663 PHE PHE A . n 
A 1 664 ASP 664 664 664 ASP ASP A . n 
A 1 665 ASP 665 665 665 ASP ASP A . n 
A 1 666 LYS 666 666 666 LYS LYS A . n 
A 1 667 LEU 667 667 667 LEU LEU A . n 
A 1 668 MET 668 668 668 MET MET A . n 
A 1 669 THR 669 669 669 THR THR A . n 
A 1 670 TRP 670 670 670 TRP TRP A . n 
A 1 671 GLY 671 671 671 GLY GLY A . n 
A 1 672 PHE 672 672 672 PHE PHE A . n 
A 1 673 TRP 673 673 673 TRP TRP A . n 
A 1 674 LEU 674 674 674 LEU LEU A . n 
A 1 675 LEU 675 675 675 LEU LEU A . n 
A 1 676 ASN 676 676 676 ASN ASN A . n 
A 1 677 GLY 677 677 677 GLY GLY A . n 
A 1 678 GLY 678 678 678 GLY GLY A . n 
A 1 679 LEU 679 679 679 LEU LEU A . n 
A 1 680 VAL 680 680 680 VAL VAL A . n 
A 1 681 GLY 681 681 681 GLY GLY A . n 
A 1 682 MET 682 682 682 MET MET A . n 
A 1 683 ILE 683 683 683 ILE ILE A . n 
A 1 684 ALA 684 684 684 ALA ALA A . n 
A 1 685 ILE 685 685 685 ILE ILE A . n 
A 1 686 SER 686 686 686 SER SER A . n 
A 1 687 LEU 687 687 687 LEU LEU A . n 
A 1 688 LEU 688 688 688 LEU LEU A . n 
A 1 689 PRO 689 689 689 PRO PRO A . n 
A 1 690 VAL 690 690 690 VAL VAL A . n 
A 1 691 GLY 691 691 691 GLY GLY A . n 
A 1 692 VAL 692 692 692 VAL VAL A . n 
A 1 693 ILE 693 693 693 ILE ILE A . n 
A 1 694 GLN 694 694 694 GLN GLN A . n 
A 1 695 ALA 695 695 695 ALA ALA A . n 
A 1 696 TYR 696 696 696 TYR TYR A . n 
A 1 697 ALA 697 697 697 ALA ALA A . n 
A 1 698 SER 698 698 698 SER SER A . n 
A 1 699 ILE 699 699 699 ILE ILE A . n 
A 1 700 THR 700 700 700 THR THR A . n 
A 1 701 HIS 701 701 701 HIS HIS A . n 
A 1 702 GLY 702 702 702 GLY GLY A . n 
A 1 703 LEU 703 703 703 LEU LEU A . n 
A 1 704 TRP 704 704 704 TRP TRP A . n 
A 1 705 TYR 705 705 705 TYR TYR A . n 
A 1 706 ALA 706 706 706 ALA ALA A . n 
A 1 707 ARG 707 707 707 ARG ARG A . n 
A 1 708 SER 708 708 708 SER SER A . n 
A 1 709 GLU 709 709 709 GLU GLU A . n 
A 1 710 GLU 710 710 710 GLU GLU A . n 
A 1 711 PHE 711 711 711 PHE PHE A . n 
A 1 712 LEU 712 712 712 LEU LEU A . n 
A 1 713 GLN 713 713 713 GLN GLN A . n 
A 1 714 MET 714 714 714 MET MET A . n 
A 1 715 GLU 715 715 715 GLU GLU A . n 
A 1 716 ILE 716 716 716 ILE ILE A . n 
A 1 717 LEU 717 717 717 LEU LEU A . n 
A 1 718 ASP 718 718 718 ASP ASP A . n 
A 1 719 THR 719 719 719 THR THR A . n 
A 1 720 LEU 720 720 720 LEU LEU A . n 
A 1 721 ARG 721 721 721 ARG ARG A . n 
A 1 722 TRP 722 722 722 TRP TRP A . n 
A 1 723 VAL 723 723 723 VAL VAL A . n 
A 1 724 ARG 724 724 724 ARG ARG A . n 
A 1 725 THR 725 725 725 THR THR A . n 
A 1 726 ALA 726 726 726 ALA ALA A . n 
A 1 727 ALA 727 727 727 ALA ALA A . n 
A 1 728 ASP 728 728 728 ASP ASP A . n 
A 1 729 LEU 729 729 729 LEU LEU A . n 
A 1 730 ILE 730 730 730 ILE ILE A . n 
A 1 731 PHE 731 731 731 PHE PHE A . n 
A 1 732 ILE 732 732 732 ILE ILE A . n 
A 1 733 GLY 733 733 733 GLY GLY A . n 
A 1 734 GLY 734 734 734 GLY GLY A . n 
A 1 735 ALA 735 735 735 ALA ALA A . n 
A 1 736 ILE 736 736 736 ILE ILE A . n 
A 1 737 CYS 737 737 737 CYS CYS A . n 
A 1 738 VAL 738 738 738 VAL VAL A . n 
A 1 739 ALA 739 739 739 ALA ALA A . n 
A 1 740 ILE 740 740 740 ILE ILE A . n 
A 1 741 GLN 741 741 741 GLN GLN A . n 
A 1 742 ALA 742 742 742 ALA ALA A . n 
A 1 743 THR 743 743 743 THR THR A . n 
A 1 744 LYS 744 744 744 LYS LYS A . n 
A 1 745 ILE 745 745 745 ILE ILE A . n 
A 1 746 VAL 746 746 746 VAL VAL A . n 
A 1 747 PHE 747 747 ?   ?   ?   A . n 
A 1 748 GLY 748 748 ?   ?   ?   A . n 
A 1 749 ARG 749 749 ?   ?   ?   A . n 
A 1 750 ASP 750 750 ?   ?   ?   A . n 
A 1 751 LYS 751 751 ?   ?   ?   A . n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
B 2 HEM 1  801 801 HEM HEM A . 
C 2 HEM 1  802 802 HEM HEM A . 
D 3 FE  1  803 803 FE  FE  A . 
E 4 CA  1  804 804 CA  CA  A . 
F 5 HOH 1  901 4   HOH HOH A . 
F 5 HOH 2  902 24  HOH HOH A . 
F 5 HOH 3  903 32  HOH HOH A . 
F 5 HOH 4  904 29  HOH HOH A . 
F 5 HOH 5  905 20  HOH HOH A . 
F 5 HOH 6  906 28  HOH HOH A . 
F 5 HOH 7  907 14  HOH HOH A . 
F 5 HOH 8  908 30  HOH HOH A . 
F 5 HOH 9  909 8   HOH HOH A . 
F 5 HOH 10 910 2   HOH HOH A . 
F 5 HOH 11 911 21  HOH HOH A . 
F 5 HOH 12 912 15  HOH HOH A . 
F 5 HOH 13 913 10  HOH HOH A . 
F 5 HOH 14 914 23  HOH HOH A . 
F 5 HOH 15 915 16  HOH HOH A . 
F 5 HOH 16 916 27  HOH HOH A . 
F 5 HOH 17 917 7   HOH HOH A . 
F 5 HOH 18 918 22  HOH HOH A . 
F 5 HOH 19 919 6   HOH HOH A . 
F 5 HOH 20 920 25  HOH HOH A . 
F 5 HOH 21 921 31  HOH HOH A . 
F 5 HOH 22 922 13  HOH HOH A . 
F 5 HOH 23 923 11  HOH HOH A . 
F 5 HOH 24 924 26  HOH HOH A . 
F 5 HOH 25 925 19  HOH HOH A . 
F 5 HOH 26 926 18  HOH HOH A . 
F 5 HOH 27 927 1   HOH HOH A . 
F 5 HOH 28 928 12  HOH HOH A . 
F 5 HOH 29 929 17  HOH HOH A . 
F 5 HOH 30 930 9   HOH HOH A . 
F 5 HOH 31 931 5   HOH HOH A . 
F 5 HOH 32 932 3   HOH HOH A . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 A GLU 259 ? CG  ? A GLU 259 CG  
2  1 Y 1 A GLU 259 ? CD  ? A GLU 259 CD  
3  1 Y 1 A GLU 259 ? OE1 ? A GLU 259 OE1 
4  1 Y 1 A GLU 259 ? OE2 ? A GLU 259 OE2 
5  1 Y 1 A GLU 261 ? CG  ? A GLU 261 CG  
6  1 Y 1 A GLU 261 ? CD  ? A GLU 261 CD  
7  1 Y 1 A GLU 261 ? OE1 ? A GLU 261 OE1 
8  1 Y 1 A GLU 261 ? OE2 ? A GLU 261 OE2 
9  1 Y 1 A GLU 265 ? CG  ? A GLU 265 CG  
10 1 Y 1 A GLU 265 ? CD  ? A GLU 265 CD  
11 1 Y 1 A GLU 265 ? OE1 ? A GLU 265 OE1 
12 1 Y 1 A GLU 265 ? OE2 ? A GLU 265 OE2 
13 1 Y 1 A ASP 266 ? CG  ? A ASP 266 CG  
14 1 Y 1 A ASP 266 ? OD1 ? A ASP 266 OD1 
15 1 Y 1 A ASP 266 ? OD2 ? A ASP 266 OD2 
16 1 Y 1 A LYS 270 ? CG  ? A LYS 270 CG  
17 1 Y 1 A LYS 270 ? CD  ? A LYS 270 CD  
18 1 Y 1 A LYS 270 ? CE  ? A LYS 270 CE  
19 1 Y 1 A LYS 270 ? NZ  ? A LYS 270 NZ  
20 1 Y 1 A TYR 312 ? CG  ? A TYR 312 CG  
21 1 Y 1 A TYR 312 ? CD1 ? A TYR 312 CD1 
22 1 Y 1 A TYR 312 ? CD2 ? A TYR 312 CD2 
23 1 Y 1 A TYR 312 ? CE1 ? A TYR 312 CE1 
24 1 Y 1 A TYR 312 ? CE2 ? A TYR 312 CE2 
25 1 Y 1 A TYR 312 ? CZ  ? A TYR 312 CZ  
26 1 Y 1 A TYR 312 ? OH  ? A TYR 312 OH  
27 1 Y 1 A ILE 314 ? CG1 ? A ILE 314 CG1 
28 1 Y 1 A ILE 314 ? CG2 ? A ILE 314 CG2 
29 1 Y 1 A ILE 314 ? CD1 ? A ILE 314 CD1 
30 1 Y 1 A TYR 580 ? CG  ? A TYR 580 CG  
31 1 Y 1 A TYR 580 ? CD1 ? A TYR 580 CD1 
32 1 Y 1 A TYR 580 ? CD2 ? A TYR 580 CD2 
33 1 Y 1 A TYR 580 ? CE1 ? A TYR 580 CE1 
34 1 Y 1 A TYR 580 ? CE2 ? A TYR 580 CE2 
35 1 Y 1 A TYR 580 ? CZ  ? A TYR 580 CZ  
36 1 Y 1 A TYR 580 ? OH  ? A TYR 580 OH  
37 1 Y 1 A GLN 581 ? CG  ? A GLN 581 CG  
38 1 Y 1 A GLN 581 ? CD  ? A GLN 581 CD  
39 1 Y 1 A GLN 581 ? OE1 ? A GLN 581 OE1 
40 1 Y 1 A GLN 581 ? NE2 ? A GLN 581 NE2 
41 1 Y 1 A HIS 582 ? CG  ? A HIS 582 CG  
42 1 Y 1 A HIS 582 ? ND1 ? A HIS 582 ND1 
43 1 Y 1 A HIS 582 ? CD2 ? A HIS 582 CD2 
44 1 Y 1 A HIS 582 ? CE1 ? A HIS 582 CE1 
45 1 Y 1 A HIS 582 ? NE2 ? A HIS 582 NE2 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8ZGO 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8ZGO 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8ZGO 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.entry_id                                 8ZGO 
_refine.pdbx_diffrn_id                           ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             ? 
_refine.ls_d_res_high                            . 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.B_iso_mean                               ? 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_ksol                 ? 
_refine.solvent_model_param_bsol                 ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.details                                  ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.003 ? 6144 ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.591 ? 8405 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 7.036 ? 809  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.039 ? 905  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.004 ? 1031 ? f_plane_restr      ? ? 
# 
_struct.entry_id                     8ZGO 
_struct.title                        
'CryoEM structure of monomeric quinol dependent nitric oxide reductase from Neisseria meningitidis' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8ZGO 
_struct_keywords.text            'Monomer, Heme, Redox, Nitric Oxide, OXIDOREDUCTASE' 
_struct_keywords.pdbx_keywords   OXIDOREDUCTASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 2 ? 
D N N 3 ? 
E N N 4 ? 
F N N 5 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    C6S880_NEIML 
_struct_ref.pdbx_db_accession          C6S880 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MGQYKKLWYLLFAVLAVCFTILGYMGSEVYKKAPPYPEQVVSASGKVLMAKDDILAGQSAWQTTGGMEVGSVLGHGAYQA
PDWTADWLHRELSAWLDLTAQQTYGKKFDEVSPEEQAVLKTRLADEYRNQSRIKEDGSVVISDTRVKAIESILPYYHGVY
GDDPALQTTREHFAMKNNTLPSQEAREKLFDFFFWTSWSASTNRPDETFTYTNNWPHEPLINNVPTTENYMWSFTSVVLL
LMGIGLLMWGYSFLTKHEEVEVPTEDPISKVQLTPSQKALGKYVFLTVALFVVQVLLGGLTAHYTVEGQGFYGIDEALGF
EMSDWFPYALTRTWHIQSAIFWIATGFLTAGLFLAPIVNGGKDPKFQRAGVNFLYIALFIVVGGSYAGNFFALTHILPPE
FNFWFGHQGYEYLDLGRFWQLLLMVGLLLWLFLMLRCTVSAFKEKGVDKNLLAIFVASMVGVGVFYAPGLFYGEKSPIAV
MEYWRWWVVHLWVEGFFEVFATAAFAFVFYNMGFVRRSTATASTLAAAAIFMLGGVPGTLHHLYFSGSTSASMAIGACFS
ALEVVPLVLLGREAYEHWSYQHLSEWAKRLRWPLMCFVAVAFWNMIGAGVFGFLINPPISLFYIQGLNTSAVHAHAALFG
VYGFLALGFVLLVARYLKPNVQFDDKLMTWGFWLLNGGLVGMIAISLLPVGVIQAYASITHGLWYARSEEFLQMEILDTL
RWVRTAADLIFIGGAICVAIQATKIVFGRDK
;
_struct_ref.pdbx_align_begin           1 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              8ZGO 
_struct_ref_seq.pdbx_strand_id                A 
_struct_ref_seq.seq_align_beg                 1 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 751 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             C6S880 
_struct_ref_seq.db_align_beg                  1 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  751 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       1 
_struct_ref_seq.pdbx_auth_seq_align_end       751 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   monomeric 
_pdbx_struct_assembly.oligomeric_count     1 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 MET A 1   ? GLN A 3   ? MET A 1   GLN A 3   5 ? 3  
HELX_P HELX_P2  AA2 TYR A 4   ? ALA A 33  ? TYR A 4   ALA A 33  1 ? 30 
HELX_P HELX_P3  AA3 LYS A 51  ? THR A 64  ? LYS A 51  THR A 64  1 ? 14 
HELX_P HELX_P4  AA4 GLY A 65  ? VAL A 69  ? GLY A 65  VAL A 69  5 ? 5  
HELX_P HELX_P5  AA5 ASP A 82  ? GLY A 105 ? ASP A 82  GLY A 105 1 ? 24 
HELX_P HELX_P6  AA6 SER A 112 ? ASN A 129 ? SER A 112 ASN A 129 1 ? 18 
HELX_P HELX_P7  AA7 SER A 142 ? GLY A 161 ? SER A 142 GLY A 161 1 ? 20 
HELX_P HELX_P8  AA8 ASP A 163 ? ALA A 165 ? ASP A 163 ALA A 165 5 ? 3  
HELX_P HELX_P9  AA9 LEU A 166 ? PHE A 173 ? LEU A 166 PHE A 173 1 ? 8  
HELX_P HELX_P10 AB1 SER A 182 ? ALA A 200 ? SER A 182 ALA A 200 1 ? 19 
HELX_P HELX_P11 AB2 THR A 226 ? THR A 255 ? THR A 226 THR A 255 1 ? 30 
HELX_P HELX_P12 AB3 SER A 276 ? ALA A 279 ? SER A 276 ALA A 279 5 ? 4  
HELX_P HELX_P13 AB4 LEU A 280 ? THR A 305 ? LEU A 280 THR A 305 1 ? 26 
HELX_P HELX_P14 AB5 GLU A 321 ? PHE A 326 ? GLU A 321 PHE A 326 1 ? 6  
HELX_P HELX_P15 AB6 PRO A 327 ? ASN A 359 ? PRO A 327 ASN A 359 1 ? 33 
HELX_P HELX_P16 AB7 PHE A 366 ? THR A 394 ? PHE A 366 THR A 394 1 ? 29 
HELX_P HELX_P17 AB8 PRO A 398 ? GLU A 400 ? PRO A 398 GLU A 400 5 ? 3  
HELX_P HELX_P18 AB9 PHE A 401 ? GLY A 406 ? PHE A 401 GLY A 406 1 ? 6  
HELX_P HELX_P19 AC1 GLY A 416 ? ARG A 436 ? GLY A 416 ARG A 436 1 ? 21 
HELX_P HELX_P20 AC2 THR A 438 ? LYS A 443 ? THR A 438 LYS A 443 1 ? 6  
HELX_P HELX_P21 AC3 LYS A 449 ? PHE A 465 ? LYS A 449 PHE A 465 1 ? 17 
HELX_P HELX_P22 AC4 TYR A 466 ? PHE A 471 ? TYR A 466 PHE A 471 5 ? 6  
HELX_P HELX_P23 AC5 PRO A 477 ? HIS A 490 ? PRO A 477 HIS A 490 1 ? 14 
HELX_P HELX_P24 AC6 PHE A 497 ? MET A 512 ? PHE A 497 MET A 512 1 ? 16 
HELX_P HELX_P25 AC7 ARG A 516 ? VAL A 536 ? ARG A 516 VAL A 536 1 ? 21 
HELX_P HELX_P26 AC8 PRO A 537 ? LEU A 543 ? PRO A 537 LEU A 543 5 ? 7  
HELX_P HELX_P27 AC9 SER A 550 ? ALA A 561 ? SER A 550 ALA A 561 1 ? 12 
HELX_P HELX_P28 AD1 VAL A 564 ? LEU A 570 ? VAL A 564 LEU A 570 1 ? 7  
HELX_P HELX_P29 AD2 GLY A 571 ? SER A 579 ? GLY A 571 SER A 579 1 ? 9  
HELX_P HELX_P30 AD3 LEU A 590 ? GLY A 607 ? LEU A 590 GLY A 607 1 ? 18 
HELX_P HELX_P31 AD4 GLY A 609 ? LEU A 614 ? GLY A 609 LEU A 614 1 ? 6  
HELX_P HELX_P32 AD5 PRO A 617 ? GLN A 625 ? PRO A 617 GLN A 625 1 ? 9  
HELX_P HELX_P33 AD6 LEU A 627 ? LYS A 658 ? LEU A 627 LYS A 658 1 ? 32 
HELX_P HELX_P34 AD7 ASP A 664 ? SER A 686 ? ASP A 664 SER A 686 1 ? 23 
HELX_P HELX_P35 AD8 SER A 686 ? GLY A 702 ? SER A 686 GLY A 702 1 ? 17 
HELX_P HELX_P36 AD9 GLY A 702 ? SER A 708 ? GLY A 702 SER A 708 1 ? 7  
HELX_P HELX_P37 AE1 SER A 708 ? GLN A 713 ? SER A 708 GLN A 713 1 ? 6  
HELX_P HELX_P38 AE2 MET A 714 ? VAL A 723 ? MET A 714 VAL A 723 1 ? 10 
HELX_P HELX_P39 AE3 VAL A 723 ? VAL A 746 ? VAL A 723 VAL A 746 1 ? 24 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
metalc1  metalc ? ? A GLY 76  O   ? ? ? 1_555 E CA  . CA ? ? A GLY 76  A CA  804 1_555 ? ? ? ? ? ? ? 2.615 ? ? 
metalc2  metalc ? ? A TYR 78  OH  ? ? ? 1_555 E CA  . CA ? ? A TYR 78  A CA  804 1_555 ? ? ? ? ? ? ? 3.112 ? ? 
metalc3  metalc ? ? A HIS 335 NE2 ? ? ? 1_555 B HEM . FE ? ? A HIS 335 A HEM 801 1_555 ? ? ? ? ? ? ? 2.369 ? ? 
metalc4  metalc ? ? A GLU 411 OE1 ? ? ? 1_555 E CA  . CA ? ? A GLU 411 A CA  804 1_555 ? ? ? ? ? ? ? 2.593 ? ? 
metalc5  metalc ? ? A GLU 411 OE2 ? ? ? 1_555 E CA  . CA ? ? A GLU 411 A CA  804 1_555 ? ? ? ? ? ? ? 2.758 ? ? 
metalc6  metalc ? ? A HIS 490 ND1 ? ? ? 1_555 D FE  . FE ? ? A HIS 490 A FE  803 1_555 ? ? ? ? ? ? ? 2.266 ? ? 
metalc7  metalc ? ? A GLU 494 OE2 ? ? ? 1_555 D FE  . FE ? ? A GLU 494 A FE  803 1_555 ? ? ? ? ? ? ? 2.566 ? ? 
metalc8  metalc ? ? A HIS 541 NE2 ? ? ? 1_555 D FE  . FE ? ? A HIS 541 A FE  803 1_555 ? ? ? ? ? ? ? 2.377 ? ? 
metalc9  metalc ? ? A HIS 542 NE2 ? ? ? 1_555 D FE  . FE ? ? A HIS 542 A FE  803 1_555 ? ? ? ? ? ? ? 2.182 ? ? 
metalc10 metalc ? ? A HIS 633 NE2 ? ? ? 1_555 C HEM . FE ? ? A HIS 633 A HEM 802 1_555 ? ? ? ? ? ? ? 2.223 ? ? 
metalc11 metalc ? ? A HIS 635 NE2 ? ? ? 1_555 B HEM . FE ? ? A HIS 635 A HEM 801 1_555 ? ? ? ? ? ? ? 2.227 ? ? 
metalc12 metalc ? ? B HEM .   O1D ? ? ? 1_555 E CA  . CA ? ? A HEM 801 A CA  804 1_555 ? ? ? ? ? ? ? 2.492 ? ? 
metalc13 metalc ? ? C HEM .   O1A ? ? ? 1_555 E CA  . CA ? ? A HEM 802 A CA  804 1_555 ? ? ? ? ? ? ? 2.931 ? ? 
# 
_struct_conn_type.id          metalc 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1  O   ? A GLY 76  ? A GLY 76  ? 1_555 CA ? E CA  . ? A CA  804 ? 1_555 OH  ? A TYR 78  ? A TYR 78  ? 1_555 88.7  ? 
2  O   ? A GLY 76  ? A GLY 76  ? 1_555 CA ? E CA  . ? A CA  804 ? 1_555 OE1 ? A GLU 411 ? A GLU 411 ? 1_555 94.2  ? 
3  OH  ? A TYR 78  ? A TYR 78  ? 1_555 CA ? E CA  . ? A CA  804 ? 1_555 OE1 ? A GLU 411 ? A GLU 411 ? 1_555 159.7 ? 
4  O   ? A GLY 76  ? A GLY 76  ? 1_555 CA ? E CA  . ? A CA  804 ? 1_555 OE2 ? A GLU 411 ? A GLU 411 ? 1_555 95.3  ? 
5  OH  ? A TYR 78  ? A TYR 78  ? 1_555 CA ? E CA  . ? A CA  804 ? 1_555 OE2 ? A GLU 411 ? A GLU 411 ? 1_555 151.5 ? 
6  OE1 ? A GLU 411 ? A GLU 411 ? 1_555 CA ? E CA  . ? A CA  804 ? 1_555 OE2 ? A GLU 411 ? A GLU 411 ? 1_555 48.2  ? 
7  O   ? A GLY 76  ? A GLY 76  ? 1_555 CA ? E CA  . ? A CA  804 ? 1_555 O1D ? B HEM .   ? A HEM 801 ? 1_555 112.1 ? 
8  OH  ? A TYR 78  ? A TYR 78  ? 1_555 CA ? E CA  . ? A CA  804 ? 1_555 O1D ? B HEM .   ? A HEM 801 ? 1_555 80.5  ? 
9  OE1 ? A GLU 411 ? A GLU 411 ? 1_555 CA ? E CA  . ? A CA  804 ? 1_555 O1D ? B HEM .   ? A HEM 801 ? 1_555 116.6 ? 
10 OE2 ? A GLU 411 ? A GLU 411 ? 1_555 CA ? E CA  . ? A CA  804 ? 1_555 O1D ? B HEM .   ? A HEM 801 ? 1_555 71.9  ? 
11 O   ? A GLY 76  ? A GLY 76  ? 1_555 CA ? E CA  . ? A CA  804 ? 1_555 O1A ? C HEM .   ? A HEM 802 ? 1_555 171.7 ? 
12 OH  ? A TYR 78  ? A TYR 78  ? 1_555 CA ? E CA  . ? A CA  804 ? 1_555 O1A ? C HEM .   ? A HEM 802 ? 1_555 90.6  ? 
13 OE1 ? A GLU 411 ? A GLU 411 ? 1_555 CA ? E CA  . ? A CA  804 ? 1_555 O1A ? C HEM .   ? A HEM 802 ? 1_555 83.7  ? 
14 OE2 ? A GLU 411 ? A GLU 411 ? 1_555 CA ? E CA  . ? A CA  804 ? 1_555 O1A ? C HEM .   ? A HEM 802 ? 1_555 89.3  ? 
15 O1D ? B HEM .   ? A HEM 801 ? 1_555 CA ? E CA  . ? A CA  804 ? 1_555 O1A ? C HEM .   ? A HEM 802 ? 1_555 75.9  ? 
16 NE2 ? A HIS 335 ? A HIS 335 ? 1_555 FE ? B HEM . ? A HEM 801 ? 1_555 NA  ? B HEM .   ? A HEM 801 ? 1_555 97.7  ? 
17 NE2 ? A HIS 335 ? A HIS 335 ? 1_555 FE ? B HEM . ? A HEM 801 ? 1_555 NB  ? B HEM .   ? A HEM 801 ? 1_555 84.9  ? 
18 NA  ? B HEM .   ? A HEM 801 ? 1_555 FE ? B HEM . ? A HEM 801 ? 1_555 NB  ? B HEM .   ? A HEM 801 ? 1_555 88.7  ? 
19 NE2 ? A HIS 335 ? A HIS 335 ? 1_555 FE ? B HEM . ? A HEM 801 ? 1_555 NC  ? B HEM .   ? A HEM 801 ? 1_555 86.3  ? 
20 NA  ? B HEM .   ? A HEM 801 ? 1_555 FE ? B HEM . ? A HEM 801 ? 1_555 NC  ? B HEM .   ? A HEM 801 ? 1_555 173.8 ? 
21 NB  ? B HEM .   ? A HEM 801 ? 1_555 FE ? B HEM . ? A HEM 801 ? 1_555 NC  ? B HEM .   ? A HEM 801 ? 1_555 86.9  ? 
22 NE2 ? A HIS 335 ? A HIS 335 ? 1_555 FE ? B HEM . ? A HEM 801 ? 1_555 ND  ? B HEM .   ? A HEM 801 ? 1_555 97.8  ? 
23 NA  ? B HEM .   ? A HEM 801 ? 1_555 FE ? B HEM . ? A HEM 801 ? 1_555 ND  ? B HEM .   ? A HEM 801 ? 1_555 92.7  ? 
24 NB  ? B HEM .   ? A HEM 801 ? 1_555 FE ? B HEM . ? A HEM 801 ? 1_555 ND  ? B HEM .   ? A HEM 801 ? 1_555 176.7 ? 
25 NC  ? B HEM .   ? A HEM 801 ? 1_555 FE ? B HEM . ? A HEM 801 ? 1_555 ND  ? B HEM .   ? A HEM 801 ? 1_555 91.4  ? 
26 NE2 ? A HIS 335 ? A HIS 335 ? 1_555 FE ? B HEM . ? A HEM 801 ? 1_555 NE2 ? A HIS 635 ? A HIS 635 ? 1_555 169.9 ? 
27 NA  ? B HEM .   ? A HEM 801 ? 1_555 FE ? B HEM . ? A HEM 801 ? 1_555 NE2 ? A HIS 635 ? A HIS 635 ? 1_555 88.6  ? 
28 NB  ? B HEM .   ? A HEM 801 ? 1_555 FE ? B HEM . ? A HEM 801 ? 1_555 NE2 ? A HIS 635 ? A HIS 635 ? 1_555 87.3  ? 
29 NC  ? B HEM .   ? A HEM 801 ? 1_555 FE ? B HEM . ? A HEM 801 ? 1_555 NE2 ? A HIS 635 ? A HIS 635 ? 1_555 86.8  ? 
30 ND  ? B HEM .   ? A HEM 801 ? 1_555 FE ? B HEM . ? A HEM 801 ? 1_555 NE2 ? A HIS 635 ? A HIS 635 ? 1_555 89.8  ? 
31 ND1 ? A HIS 490 ? A HIS 490 ? 1_555 FE ? D FE  . ? A FE  803 ? 1_555 OE2 ? A GLU 494 ? A GLU 494 ? 1_555 85.6  ? 
32 ND1 ? A HIS 490 ? A HIS 490 ? 1_555 FE ? D FE  . ? A FE  803 ? 1_555 NE2 ? A HIS 541 ? A HIS 541 ? 1_555 101.6 ? 
33 OE2 ? A GLU 494 ? A GLU 494 ? 1_555 FE ? D FE  . ? A FE  803 ? 1_555 NE2 ? A HIS 541 ? A HIS 541 ? 1_555 170.8 ? 
34 ND1 ? A HIS 490 ? A HIS 490 ? 1_555 FE ? D FE  . ? A FE  803 ? 1_555 NE2 ? A HIS 542 ? A HIS 542 ? 1_555 90.2  ? 
35 OE2 ? A GLU 494 ? A GLU 494 ? 1_555 FE ? D FE  . ? A FE  803 ? 1_555 NE2 ? A HIS 542 ? A HIS 542 ? 1_555 106.4 ? 
36 NE2 ? A HIS 541 ? A HIS 541 ? 1_555 FE ? D FE  . ? A FE  803 ? 1_555 NE2 ? A HIS 542 ? A HIS 542 ? 1_555 79.6  ? 
37 NE2 ? A HIS 633 ? A HIS 633 ? 1_555 FE ? C HEM . ? A HEM 802 ? 1_555 NA  ? C HEM .   ? A HEM 802 ? 1_555 93.3  ? 
38 NE2 ? A HIS 633 ? A HIS 633 ? 1_555 FE ? C HEM . ? A HEM 802 ? 1_555 NB  ? C HEM .   ? A HEM 802 ? 1_555 88.1  ? 
39 NA  ? C HEM .   ? A HEM 802 ? 1_555 FE ? C HEM . ? A HEM 802 ? 1_555 NB  ? C HEM .   ? A HEM 802 ? 1_555 87.7  ? 
40 NE2 ? A HIS 633 ? A HIS 633 ? 1_555 FE ? C HEM . ? A HEM 802 ? 1_555 NC  ? C HEM .   ? A HEM 802 ? 1_555 89.6  ? 
41 NA  ? C HEM .   ? A HEM 802 ? 1_555 FE ? C HEM . ? A HEM 802 ? 1_555 NC  ? C HEM .   ? A HEM 802 ? 1_555 173.5 ? 
42 NB  ? C HEM .   ? A HEM 802 ? 1_555 FE ? C HEM . ? A HEM 802 ? 1_555 NC  ? C HEM .   ? A HEM 802 ? 1_555 86.6  ? 
43 NE2 ? A HIS 633 ? A HIS 633 ? 1_555 FE ? C HEM . ? A HEM 802 ? 1_555 ND  ? C HEM .   ? A HEM 802 ? 1_555 93.9  ? 
44 NA  ? C HEM .   ? A HEM 802 ? 1_555 FE ? C HEM . ? A HEM 802 ? 1_555 ND  ? C HEM .   ? A HEM 802 ? 1_555 93.9  ? 
45 NB  ? C HEM .   ? A HEM 802 ? 1_555 FE ? C HEM . ? A HEM 802 ? 1_555 ND  ? C HEM .   ? A HEM 802 ? 1_555 177.3 ? 
46 NC  ? C HEM .   ? A HEM 802 ? 1_555 FE ? C HEM . ? A HEM 802 ? 1_555 ND  ? C HEM .   ? A HEM 802 ? 1_555 91.7  ? 
# 
_struct_mon_prot_cis.pdbx_id                1 
_struct_mon_prot_cis.label_comp_id          TRP 
_struct_mon_prot_cis.label_seq_id           215 
_struct_mon_prot_cis.label_asym_id          A 
_struct_mon_prot_cis.label_alt_id           . 
_struct_mon_prot_cis.pdbx_PDB_ins_code      ? 
_struct_mon_prot_cis.auth_comp_id           TRP 
_struct_mon_prot_cis.auth_seq_id            215 
_struct_mon_prot_cis.auth_asym_id           A 
_struct_mon_prot_cis.pdbx_label_comp_id_2   PRO 
_struct_mon_prot_cis.pdbx_label_seq_id_2    216 
_struct_mon_prot_cis.pdbx_label_asym_id_2   A 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2    ? 
_struct_mon_prot_cis.pdbx_auth_comp_id_2    PRO 
_struct_mon_prot_cis.pdbx_auth_seq_id_2     216 
_struct_mon_prot_cis.pdbx_auth_asym_id_2    A 
_struct_mon_prot_cis.pdbx_PDB_model_num     1 
_struct_mon_prot_cis.pdbx_omega_angle       -1.58 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 3 ? 
AA2 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? parallel      
AA2 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 VAL A 47  ? ALA A 50  ? VAL A 47  ALA A 50  
AA1 2 GLN A 39  ? SER A 42  ? GLN A 39  SER A 42  
AA1 3 SER A 138 ? ILE A 141 ? SER A 138 ILE A 141 
AA2 1 SER A 71  ? VAL A 72  ? SER A 71  VAL A 72  
AA2 2 HIS A 75  ? GLY A 76  ? HIS A 75  GLY A 76  
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O LEU A 48 ? O LEU A 48 N VAL A 40  ? N VAL A 40  
AA1 2 3 N VAL A 41 ? N VAL A 41 O VAL A 139 ? O VAL A 139 
AA2 1 2 N VAL A 72 ? N VAL A 72 O HIS A 75  ? O HIS A 75  
# 
_pdbx_entry_details.entry_id                   8ZGO 
_pdbx_entry_details.has_ligand_of_interest     N 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1 1 O  A GLN 62  ? ? C A GLN 62  ? ? N  A THR 63  ? ? 113.08 122.70 -9.62  1.60 Y 
2 1 CA A PRO 267 ? ? N A PRO 267 ? ? CD A PRO 267 ? ? 98.59  111.70 -13.11 1.40 N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 GLU A 110 ? ? -87.59  45.75   
2 1 TYR A 312 ? ? 49.44   -126.32 
3 1 PHE A 366 ? ? 86.55   23.63   
4 1 TYR A 412 ? ? 72.07   -6.00   
5 1 PHE A 496 ? ? 67.53   -7.03   
6 1 LEU A 590 ? ? -99.34  34.15   
7 1 VAL A 641 ? ? -95.67  -63.88  
8 1 SER A 686 ? ? -123.89 -56.70  
# 
_pdbx_validate_planes.id              1 
_pdbx_validate_planes.PDB_model_num   1 
_pdbx_validate_planes.auth_comp_id    ARG 
_pdbx_validate_planes.auth_asym_id    A 
_pdbx_validate_planes.auth_seq_id     516 
_pdbx_validate_planes.PDB_ins_code    ? 
_pdbx_validate_planes.label_alt_id    ? 
_pdbx_validate_planes.rmsd            0.097 
_pdbx_validate_planes.type            'SIDE CHAIN' 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8ZGO 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         REAL 
_em_3d_fitting.ref_protocol      'RIGID BODY FIT' 
# 
_em_3d_reconstruction.entry_id                    8ZGO 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  2.25 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               274346 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            8 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'Monomeric quinol dependent nitric oxide reductase' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_imaging.entry_id                        8ZGO 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'JEOL CRYO ARM 300' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           'JEOL CRYOSPECPORTER' 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      2.7 
_em_imaging.nominal_defocus_min             1200 
_em_imaging.nominal_defocus_max             1600 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           60000 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   77 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             'COMA FREE' 
_em_imaging.c2_aperture_diameter            50.0 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         NITROGEN 
# 
_em_sample_support.id               1 
_em_sample_support.film_material    ? 
_em_sample_support.method           ? 
_em_sample_support.grid_material    COPPER 
_em_sample_support.grid_mesh_size   300 
_em_sample_support.grid_type        'Quantifoil R1.2/1.3' 
_em_sample_support.details          ? 
_em_sample_support.specimen_id      1 
_em_sample_support.citation_id      ? 
# 
_em_vitrification.entry_id              8ZGO 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              100 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   281 
_em_vitrification.instrument            'FEI VITROBOT MARK IV' 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               'Blot foce 3, blot time 3s' 
# 
_em_experiment.entry_id                8ZGO 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1 1 Y 1 A ILE 268 ? A ILE 268 
2 1 Y 1 A ASP 315 ? A ASP 315 
3 1 Y 1 A GLU 316 ? A GLU 316 
4 1 Y 1 A ALA 317 ? A ALA 317 
5 1 Y 1 A PHE 747 ? A PHE 747 
6 1 Y 1 A GLY 748 ? A GLY 748 
7 1 Y 1 A ARG 749 ? A ARG 749 
8 1 Y 1 A ASP 750 ? A ASP 750 
9 1 Y 1 A LYS 751 ? A LYS 751 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N  N N 1   
ALA CA   C  N S 2   
ALA C    C  N N 3   
ALA O    O  N N 4   
ALA CB   C  N N 5   
ALA OXT  O  N N 6   
ALA H    H  N N 7   
ALA H2   H  N N 8   
ALA HA   H  N N 9   
ALA HB1  H  N N 10  
ALA HB2  H  N N 11  
ALA HB3  H  N N 12  
ALA HXT  H  N N 13  
ARG N    N  N N 14  
ARG CA   C  N S 15  
ARG C    C  N N 16  
ARG O    O  N N 17  
ARG CB   C  N N 18  
ARG CG   C  N N 19  
ARG CD   C  N N 20  
ARG NE   N  N N 21  
ARG CZ   C  N N 22  
ARG NH1  N  N N 23  
ARG NH2  N  N N 24  
ARG OXT  O  N N 25  
ARG H    H  N N 26  
ARG H2   H  N N 27  
ARG HA   H  N N 28  
ARG HB2  H  N N 29  
ARG HB3  H  N N 30  
ARG HG2  H  N N 31  
ARG HG3  H  N N 32  
ARG HD2  H  N N 33  
ARG HD3  H  N N 34  
ARG HE   H  N N 35  
ARG HH11 H  N N 36  
ARG HH12 H  N N 37  
ARG HH21 H  N N 38  
ARG HH22 H  N N 39  
ARG HXT  H  N N 40  
ASN N    N  N N 41  
ASN CA   C  N S 42  
ASN C    C  N N 43  
ASN O    O  N N 44  
ASN CB   C  N N 45  
ASN CG   C  N N 46  
ASN OD1  O  N N 47  
ASN ND2  N  N N 48  
ASN OXT  O  N N 49  
ASN H    H  N N 50  
ASN H2   H  N N 51  
ASN HA   H  N N 52  
ASN HB2  H  N N 53  
ASN HB3  H  N N 54  
ASN HD21 H  N N 55  
ASN HD22 H  N N 56  
ASN HXT  H  N N 57  
ASP N    N  N N 58  
ASP CA   C  N S 59  
ASP C    C  N N 60  
ASP O    O  N N 61  
ASP CB   C  N N 62  
ASP CG   C  N N 63  
ASP OD1  O  N N 64  
ASP OD2  O  N N 65  
ASP OXT  O  N N 66  
ASP H    H  N N 67  
ASP H2   H  N N 68  
ASP HA   H  N N 69  
ASP HB2  H  N N 70  
ASP HB3  H  N N 71  
ASP HD2  H  N N 72  
ASP HXT  H  N N 73  
CA  CA   CA N N 74  
CYS N    N  N N 75  
CYS CA   C  N R 76  
CYS C    C  N N 77  
CYS O    O  N N 78  
CYS CB   C  N N 79  
CYS SG   S  N N 80  
CYS OXT  O  N N 81  
CYS H    H  N N 82  
CYS H2   H  N N 83  
CYS HA   H  N N 84  
CYS HB2  H  N N 85  
CYS HB3  H  N N 86  
CYS HG   H  N N 87  
CYS HXT  H  N N 88  
FE  FE   FE N N 89  
GLN N    N  N N 90  
GLN CA   C  N S 91  
GLN C    C  N N 92  
GLN O    O  N N 93  
GLN CB   C  N N 94  
GLN CG   C  N N 95  
GLN CD   C  N N 96  
GLN OE1  O  N N 97  
GLN NE2  N  N N 98  
GLN OXT  O  N N 99  
GLN H    H  N N 100 
GLN H2   H  N N 101 
GLN HA   H  N N 102 
GLN HB2  H  N N 103 
GLN HB3  H  N N 104 
GLN HG2  H  N N 105 
GLN HG3  H  N N 106 
GLN HE21 H  N N 107 
GLN HE22 H  N N 108 
GLN HXT  H  N N 109 
GLU N    N  N N 110 
GLU CA   C  N S 111 
GLU C    C  N N 112 
GLU O    O  N N 113 
GLU CB   C  N N 114 
GLU CG   C  N N 115 
GLU CD   C  N N 116 
GLU OE1  O  N N 117 
GLU OE2  O  N N 118 
GLU OXT  O  N N 119 
GLU H    H  N N 120 
GLU H2   H  N N 121 
GLU HA   H  N N 122 
GLU HB2  H  N N 123 
GLU HB3  H  N N 124 
GLU HG2  H  N N 125 
GLU HG3  H  N N 126 
GLU HE2  H  N N 127 
GLU HXT  H  N N 128 
GLY N    N  N N 129 
GLY CA   C  N N 130 
GLY C    C  N N 131 
GLY O    O  N N 132 
GLY OXT  O  N N 133 
GLY H    H  N N 134 
GLY H2   H  N N 135 
GLY HA2  H  N N 136 
GLY HA3  H  N N 137 
GLY HXT  H  N N 138 
HEM CHA  C  N N 139 
HEM CHB  C  N N 140 
HEM CHC  C  N N 141 
HEM CHD  C  N N 142 
HEM C1A  C  Y N 143 
HEM C2A  C  Y N 144 
HEM C3A  C  Y N 145 
HEM C4A  C  Y N 146 
HEM CMA  C  N N 147 
HEM CAA  C  N N 148 
HEM CBA  C  N N 149 
HEM CGA  C  N N 150 
HEM O1A  O  N N 151 
HEM O2A  O  N N 152 
HEM C1B  C  N N 153 
HEM C2B  C  N N 154 
HEM C3B  C  N N 155 
HEM C4B  C  N N 156 
HEM CMB  C  N N 157 
HEM CAB  C  N N 158 
HEM CBB  C  N N 159 
HEM C1C  C  Y N 160 
HEM C2C  C  Y N 161 
HEM C3C  C  Y N 162 
HEM C4C  C  Y N 163 
HEM CMC  C  N N 164 
HEM CAC  C  N N 165 
HEM CBC  C  N N 166 
HEM C1D  C  N N 167 
HEM C2D  C  N N 168 
HEM C3D  C  N N 169 
HEM C4D  C  N N 170 
HEM CMD  C  N N 171 
HEM CAD  C  N N 172 
HEM CBD  C  N N 173 
HEM CGD  C  N N 174 
HEM O1D  O  N N 175 
HEM O2D  O  N N 176 
HEM NA   N  Y N 177 
HEM NB   N  N N 178 
HEM NC   N  Y N 179 
HEM ND   N  N N 180 
HEM FE   FE N N 181 
HEM HHB  H  N N 182 
HEM HHC  H  N N 183 
HEM HHD  H  N N 184 
HEM HMA  H  N N 185 
HEM HMAA H  N N 186 
HEM HMAB H  N N 187 
HEM HAA  H  N N 188 
HEM HAAA H  N N 189 
HEM HBA  H  N N 190 
HEM HBAA H  N N 191 
HEM HMB  H  N N 192 
HEM HMBA H  N N 193 
HEM HMBB H  N N 194 
HEM HAB  H  N N 195 
HEM HBB  H  N N 196 
HEM HBBA H  N N 197 
HEM HMC  H  N N 198 
HEM HMCA H  N N 199 
HEM HMCB H  N N 200 
HEM HAC  H  N N 201 
HEM HBC  H  N N 202 
HEM HBCA H  N N 203 
HEM HMD  H  N N 204 
HEM HMDA H  N N 205 
HEM HMDB H  N N 206 
HEM HAD  H  N N 207 
HEM HADA H  N N 208 
HEM HBD  H  N N 209 
HEM HBDA H  N N 210 
HEM H2A  H  N N 211 
HEM H2D  H  N N 212 
HEM HHA  H  N N 213 
HIS N    N  N N 214 
HIS CA   C  N S 215 
HIS C    C  N N 216 
HIS O    O  N N 217 
HIS CB   C  N N 218 
HIS CG   C  Y N 219 
HIS ND1  N  Y N 220 
HIS CD2  C  Y N 221 
HIS CE1  C  Y N 222 
HIS NE2  N  Y N 223 
HIS OXT  O  N N 224 
HIS H    H  N N 225 
HIS H2   H  N N 226 
HIS HA   H  N N 227 
HIS HB2  H  N N 228 
HIS HB3  H  N N 229 
HIS HD1  H  N N 230 
HIS HD2  H  N N 231 
HIS HE1  H  N N 232 
HIS HE2  H  N N 233 
HIS HXT  H  N N 234 
HOH O    O  N N 235 
HOH H1   H  N N 236 
HOH H2   H  N N 237 
ILE N    N  N N 238 
ILE CA   C  N S 239 
ILE C    C  N N 240 
ILE O    O  N N 241 
ILE CB   C  N S 242 
ILE CG1  C  N N 243 
ILE CG2  C  N N 244 
ILE CD1  C  N N 245 
ILE OXT  O  N N 246 
ILE H    H  N N 247 
ILE H2   H  N N 248 
ILE HA   H  N N 249 
ILE HB   H  N N 250 
ILE HG12 H  N N 251 
ILE HG13 H  N N 252 
ILE HG21 H  N N 253 
ILE HG22 H  N N 254 
ILE HG23 H  N N 255 
ILE HD11 H  N N 256 
ILE HD12 H  N N 257 
ILE HD13 H  N N 258 
ILE HXT  H  N N 259 
LEU N    N  N N 260 
LEU CA   C  N S 261 
LEU C    C  N N 262 
LEU O    O  N N 263 
LEU CB   C  N N 264 
LEU CG   C  N N 265 
LEU CD1  C  N N 266 
LEU CD2  C  N N 267 
LEU OXT  O  N N 268 
LEU H    H  N N 269 
LEU H2   H  N N 270 
LEU HA   H  N N 271 
LEU HB2  H  N N 272 
LEU HB3  H  N N 273 
LEU HG   H  N N 274 
LEU HD11 H  N N 275 
LEU HD12 H  N N 276 
LEU HD13 H  N N 277 
LEU HD21 H  N N 278 
LEU HD22 H  N N 279 
LEU HD23 H  N N 280 
LEU HXT  H  N N 281 
LYS N    N  N N 282 
LYS CA   C  N S 283 
LYS C    C  N N 284 
LYS O    O  N N 285 
LYS CB   C  N N 286 
LYS CG   C  N N 287 
LYS CD   C  N N 288 
LYS CE   C  N N 289 
LYS NZ   N  N N 290 
LYS OXT  O  N N 291 
LYS H    H  N N 292 
LYS H2   H  N N 293 
LYS HA   H  N N 294 
LYS HB2  H  N N 295 
LYS HB3  H  N N 296 
LYS HG2  H  N N 297 
LYS HG3  H  N N 298 
LYS HD2  H  N N 299 
LYS HD3  H  N N 300 
LYS HE2  H  N N 301 
LYS HE3  H  N N 302 
LYS HZ1  H  N N 303 
LYS HZ2  H  N N 304 
LYS HZ3  H  N N 305 
LYS HXT  H  N N 306 
MET N    N  N N 307 
MET CA   C  N S 308 
MET C    C  N N 309 
MET O    O  N N 310 
MET CB   C  N N 311 
MET CG   C  N N 312 
MET SD   S  N N 313 
MET CE   C  N N 314 
MET OXT  O  N N 315 
MET H    H  N N 316 
MET H2   H  N N 317 
MET HA   H  N N 318 
MET HB2  H  N N 319 
MET HB3  H  N N 320 
MET HG2  H  N N 321 
MET HG3  H  N N 322 
MET HE1  H  N N 323 
MET HE2  H  N N 324 
MET HE3  H  N N 325 
MET HXT  H  N N 326 
PHE N    N  N N 327 
PHE CA   C  N S 328 
PHE C    C  N N 329 
PHE O    O  N N 330 
PHE CB   C  N N 331 
PHE CG   C  Y N 332 
PHE CD1  C  Y N 333 
PHE CD2  C  Y N 334 
PHE CE1  C  Y N 335 
PHE CE2  C  Y N 336 
PHE CZ   C  Y N 337 
PHE OXT  O  N N 338 
PHE H    H  N N 339 
PHE H2   H  N N 340 
PHE HA   H  N N 341 
PHE HB2  H  N N 342 
PHE HB3  H  N N 343 
PHE HD1  H  N N 344 
PHE HD2  H  N N 345 
PHE HE1  H  N N 346 
PHE HE2  H  N N 347 
PHE HZ   H  N N 348 
PHE HXT  H  N N 349 
PRO N    N  N N 350 
PRO CA   C  N S 351 
PRO C    C  N N 352 
PRO O    O  N N 353 
PRO CB   C  N N 354 
PRO CG   C  N N 355 
PRO CD   C  N N 356 
PRO OXT  O  N N 357 
PRO H    H  N N 358 
PRO HA   H  N N 359 
PRO HB2  H  N N 360 
PRO HB3  H  N N 361 
PRO HG2  H  N N 362 
PRO HG3  H  N N 363 
PRO HD2  H  N N 364 
PRO HD3  H  N N 365 
PRO HXT  H  N N 366 
SER N    N  N N 367 
SER CA   C  N S 368 
SER C    C  N N 369 
SER O    O  N N 370 
SER CB   C  N N 371 
SER OG   O  N N 372 
SER OXT  O  N N 373 
SER H    H  N N 374 
SER H2   H  N N 375 
SER HA   H  N N 376 
SER HB2  H  N N 377 
SER HB3  H  N N 378 
SER HG   H  N N 379 
SER HXT  H  N N 380 
THR N    N  N N 381 
THR CA   C  N S 382 
THR C    C  N N 383 
THR O    O  N N 384 
THR CB   C  N R 385 
THR OG1  O  N N 386 
THR CG2  C  N N 387 
THR OXT  O  N N 388 
THR H    H  N N 389 
THR H2   H  N N 390 
THR HA   H  N N 391 
THR HB   H  N N 392 
THR HG1  H  N N 393 
THR HG21 H  N N 394 
THR HG22 H  N N 395 
THR HG23 H  N N 396 
THR HXT  H  N N 397 
TRP N    N  N N 398 
TRP CA   C  N S 399 
TRP C    C  N N 400 
TRP O    O  N N 401 
TRP CB   C  N N 402 
TRP CG   C  Y N 403 
TRP CD1  C  Y N 404 
TRP CD2  C  Y N 405 
TRP NE1  N  Y N 406 
TRP CE2  C  Y N 407 
TRP CE3  C  Y N 408 
TRP CZ2  C  Y N 409 
TRP CZ3  C  Y N 410 
TRP CH2  C  Y N 411 
TRP OXT  O  N N 412 
TRP H    H  N N 413 
TRP H2   H  N N 414 
TRP HA   H  N N 415 
TRP HB2  H  N N 416 
TRP HB3  H  N N 417 
TRP HD1  H  N N 418 
TRP HE1  H  N N 419 
TRP HE3  H  N N 420 
TRP HZ2  H  N N 421 
TRP HZ3  H  N N 422 
TRP HH2  H  N N 423 
TRP HXT  H  N N 424 
TYR N    N  N N 425 
TYR CA   C  N S 426 
TYR C    C  N N 427 
TYR O    O  N N 428 
TYR CB   C  N N 429 
TYR CG   C  Y N 430 
TYR CD1  C  Y N 431 
TYR CD2  C  Y N 432 
TYR CE1  C  Y N 433 
TYR CE2  C  Y N 434 
TYR CZ   C  Y N 435 
TYR OH   O  N N 436 
TYR OXT  O  N N 437 
TYR H    H  N N 438 
TYR H2   H  N N 439 
TYR HA   H  N N 440 
TYR HB2  H  N N 441 
TYR HB3  H  N N 442 
TYR HD1  H  N N 443 
TYR HD2  H  N N 444 
TYR HE1  H  N N 445 
TYR HE2  H  N N 446 
TYR HH   H  N N 447 
TYR HXT  H  N N 448 
VAL N    N  N N 449 
VAL CA   C  N S 450 
VAL C    C  N N 451 
VAL O    O  N N 452 
VAL CB   C  N N 453 
VAL CG1  C  N N 454 
VAL CG2  C  N N 455 
VAL OXT  O  N N 456 
VAL H    H  N N 457 
VAL H2   H  N N 458 
VAL HA   H  N N 459 
VAL HB   H  N N 460 
VAL HG11 H  N N 461 
VAL HG12 H  N N 462 
VAL HG13 H  N N 463 
VAL HG21 H  N N 464 
VAL HG22 H  N N 465 
VAL HG23 H  N N 466 
VAL HXT  H  N N 467 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HEM CHA C1A  sing N N 129 
HEM CHA C4D  doub N N 130 
HEM CHA HHA  sing N N 131 
HEM CHB C4A  sing N N 132 
HEM CHB C1B  doub N N 133 
HEM CHB HHB  sing N N 134 
HEM CHC C4B  sing N N 135 
HEM CHC C1C  doub N N 136 
HEM CHC HHC  sing N N 137 
HEM CHD C4C  doub N N 138 
HEM CHD C1D  sing N N 139 
HEM CHD HHD  sing N N 140 
HEM C1A C2A  doub Y N 141 
HEM C1A NA   sing Y N 142 
HEM C2A C3A  sing Y N 143 
HEM C2A CAA  sing N N 144 
HEM C3A C4A  doub Y N 145 
HEM C3A CMA  sing N N 146 
HEM C4A NA   sing Y N 147 
HEM CMA HMA  sing N N 148 
HEM CMA HMAA sing N N 149 
HEM CMA HMAB sing N N 150 
HEM CAA CBA  sing N N 151 
HEM CAA HAA  sing N N 152 
HEM CAA HAAA sing N N 153 
HEM CBA CGA  sing N N 154 
HEM CBA HBA  sing N N 155 
HEM CBA HBAA sing N N 156 
HEM CGA O1A  doub N N 157 
HEM CGA O2A  sing N N 158 
HEM C1B C2B  sing N N 159 
HEM C1B NB   sing N N 160 
HEM C2B C3B  doub N N 161 
HEM C2B CMB  sing N N 162 
HEM C3B C4B  sing N N 163 
HEM C3B CAB  sing N N 164 
HEM C4B NB   doub N N 165 
HEM CMB HMB  sing N N 166 
HEM CMB HMBA sing N N 167 
HEM CMB HMBB sing N N 168 
HEM CAB CBB  doub N N 169 
HEM CAB HAB  sing N N 170 
HEM CBB HBB  sing N N 171 
HEM CBB HBBA sing N N 172 
HEM C1C C2C  sing Y N 173 
HEM C1C NC   sing Y N 174 
HEM C2C C3C  doub Y N 175 
HEM C2C CMC  sing N N 176 
HEM C3C C4C  sing Y N 177 
HEM C3C CAC  sing N N 178 
HEM C4C NC   sing Y N 179 
HEM CMC HMC  sing N N 180 
HEM CMC HMCA sing N N 181 
HEM CMC HMCB sing N N 182 
HEM CAC CBC  doub N N 183 
HEM CAC HAC  sing N N 184 
HEM CBC HBC  sing N N 185 
HEM CBC HBCA sing N N 186 
HEM C1D C2D  sing N N 187 
HEM C1D ND   doub N N 188 
HEM C2D C3D  doub N N 189 
HEM C2D CMD  sing N N 190 
HEM C3D C4D  sing N N 191 
HEM C3D CAD  sing N N 192 
HEM C4D ND   sing N N 193 
HEM CMD HMD  sing N N 194 
HEM CMD HMDA sing N N 195 
HEM CMD HMDB sing N N 196 
HEM CAD CBD  sing N N 197 
HEM CAD HAD  sing N N 198 
HEM CAD HADA sing N N 199 
HEM CBD CGD  sing N N 200 
HEM CBD HBD  sing N N 201 
HEM CBD HBDA sing N N 202 
HEM CGD O1D  doub N N 203 
HEM CGD O2D  sing N N 204 
HEM O2A H2A  sing N N 205 
HEM O2D H2D  sing N N 206 
HEM FE  NA   sing N N 207 
HEM FE  NB   sing N N 208 
HEM FE  NC   sing N N 209 
HEM FE  ND   sing N N 210 
HIS N   CA   sing N N 211 
HIS N   H    sing N N 212 
HIS N   H2   sing N N 213 
HIS CA  C    sing N N 214 
HIS CA  CB   sing N N 215 
HIS CA  HA   sing N N 216 
HIS C   O    doub N N 217 
HIS C   OXT  sing N N 218 
HIS CB  CG   sing N N 219 
HIS CB  HB2  sing N N 220 
HIS CB  HB3  sing N N 221 
HIS CG  ND1  sing Y N 222 
HIS CG  CD2  doub Y N 223 
HIS ND1 CE1  doub Y N 224 
HIS ND1 HD1  sing N N 225 
HIS CD2 NE2  sing Y N 226 
HIS CD2 HD2  sing N N 227 
HIS CE1 NE2  sing Y N 228 
HIS CE1 HE1  sing N N 229 
HIS NE2 HE2  sing N N 230 
HIS OXT HXT  sing N N 231 
HOH O   H1   sing N N 232 
HOH O   H2   sing N N 233 
ILE N   CA   sing N N 234 
ILE N   H    sing N N 235 
ILE N   H2   sing N N 236 
ILE CA  C    sing N N 237 
ILE CA  CB   sing N N 238 
ILE CA  HA   sing N N 239 
ILE C   O    doub N N 240 
ILE C   OXT  sing N N 241 
ILE CB  CG1  sing N N 242 
ILE CB  CG2  sing N N 243 
ILE CB  HB   sing N N 244 
ILE CG1 CD1  sing N N 245 
ILE CG1 HG12 sing N N 246 
ILE CG1 HG13 sing N N 247 
ILE CG2 HG21 sing N N 248 
ILE CG2 HG22 sing N N 249 
ILE CG2 HG23 sing N N 250 
ILE CD1 HD11 sing N N 251 
ILE CD1 HD12 sing N N 252 
ILE CD1 HD13 sing N N 253 
ILE OXT HXT  sing N N 254 
LEU N   CA   sing N N 255 
LEU N   H    sing N N 256 
LEU N   H2   sing N N 257 
LEU CA  C    sing N N 258 
LEU CA  CB   sing N N 259 
LEU CA  HA   sing N N 260 
LEU C   O    doub N N 261 
LEU C   OXT  sing N N 262 
LEU CB  CG   sing N N 263 
LEU CB  HB2  sing N N 264 
LEU CB  HB3  sing N N 265 
LEU CG  CD1  sing N N 266 
LEU CG  CD2  sing N N 267 
LEU CG  HG   sing N N 268 
LEU CD1 HD11 sing N N 269 
LEU CD1 HD12 sing N N 270 
LEU CD1 HD13 sing N N 271 
LEU CD2 HD21 sing N N 272 
LEU CD2 HD22 sing N N 273 
LEU CD2 HD23 sing N N 274 
LEU OXT HXT  sing N N 275 
LYS N   CA   sing N N 276 
LYS N   H    sing N N 277 
LYS N   H2   sing N N 278 
LYS CA  C    sing N N 279 
LYS CA  CB   sing N N 280 
LYS CA  HA   sing N N 281 
LYS C   O    doub N N 282 
LYS C   OXT  sing N N 283 
LYS CB  CG   sing N N 284 
LYS CB  HB2  sing N N 285 
LYS CB  HB3  sing N N 286 
LYS CG  CD   sing N N 287 
LYS CG  HG2  sing N N 288 
LYS CG  HG3  sing N N 289 
LYS CD  CE   sing N N 290 
LYS CD  HD2  sing N N 291 
LYS CD  HD3  sing N N 292 
LYS CE  NZ   sing N N 293 
LYS CE  HE2  sing N N 294 
LYS CE  HE3  sing N N 295 
LYS NZ  HZ1  sing N N 296 
LYS NZ  HZ2  sing N N 297 
LYS NZ  HZ3  sing N N 298 
LYS OXT HXT  sing N N 299 
MET N   CA   sing N N 300 
MET N   H    sing N N 301 
MET N   H2   sing N N 302 
MET CA  C    sing N N 303 
MET CA  CB   sing N N 304 
MET CA  HA   sing N N 305 
MET C   O    doub N N 306 
MET C   OXT  sing N N 307 
MET CB  CG   sing N N 308 
MET CB  HB2  sing N N 309 
MET CB  HB3  sing N N 310 
MET CG  SD   sing N N 311 
MET CG  HG2  sing N N 312 
MET CG  HG3  sing N N 313 
MET SD  CE   sing N N 314 
MET CE  HE1  sing N N 315 
MET CE  HE2  sing N N 316 
MET CE  HE3  sing N N 317 
MET OXT HXT  sing N N 318 
PHE N   CA   sing N N 319 
PHE N   H    sing N N 320 
PHE N   H2   sing N N 321 
PHE CA  C    sing N N 322 
PHE CA  CB   sing N N 323 
PHE CA  HA   sing N N 324 
PHE C   O    doub N N 325 
PHE C   OXT  sing N N 326 
PHE CB  CG   sing N N 327 
PHE CB  HB2  sing N N 328 
PHE CB  HB3  sing N N 329 
PHE CG  CD1  doub Y N 330 
PHE CG  CD2  sing Y N 331 
PHE CD1 CE1  sing Y N 332 
PHE CD1 HD1  sing N N 333 
PHE CD2 CE2  doub Y N 334 
PHE CD2 HD2  sing N N 335 
PHE CE1 CZ   doub Y N 336 
PHE CE1 HE1  sing N N 337 
PHE CE2 CZ   sing Y N 338 
PHE CE2 HE2  sing N N 339 
PHE CZ  HZ   sing N N 340 
PHE OXT HXT  sing N N 341 
PRO N   CA   sing N N 342 
PRO N   CD   sing N N 343 
PRO N   H    sing N N 344 
PRO CA  C    sing N N 345 
PRO CA  CB   sing N N 346 
PRO CA  HA   sing N N 347 
PRO C   O    doub N N 348 
PRO C   OXT  sing N N 349 
PRO CB  CG   sing N N 350 
PRO CB  HB2  sing N N 351 
PRO CB  HB3  sing N N 352 
PRO CG  CD   sing N N 353 
PRO CG  HG2  sing N N 354 
PRO CG  HG3  sing N N 355 
PRO CD  HD2  sing N N 356 
PRO CD  HD3  sing N N 357 
PRO OXT HXT  sing N N 358 
SER N   CA   sing N N 359 
SER N   H    sing N N 360 
SER N   H2   sing N N 361 
SER CA  C    sing N N 362 
SER CA  CB   sing N N 363 
SER CA  HA   sing N N 364 
SER C   O    doub N N 365 
SER C   OXT  sing N N 366 
SER CB  OG   sing N N 367 
SER CB  HB2  sing N N 368 
SER CB  HB3  sing N N 369 
SER OG  HG   sing N N 370 
SER OXT HXT  sing N N 371 
THR N   CA   sing N N 372 
THR N   H    sing N N 373 
THR N   H2   sing N N 374 
THR CA  C    sing N N 375 
THR CA  CB   sing N N 376 
THR CA  HA   sing N N 377 
THR C   O    doub N N 378 
THR C   OXT  sing N N 379 
THR CB  OG1  sing N N 380 
THR CB  CG2  sing N N 381 
THR CB  HB   sing N N 382 
THR OG1 HG1  sing N N 383 
THR CG2 HG21 sing N N 384 
THR CG2 HG22 sing N N 385 
THR CG2 HG23 sing N N 386 
THR OXT HXT  sing N N 387 
TRP N   CA   sing N N 388 
TRP N   H    sing N N 389 
TRP N   H2   sing N N 390 
TRP CA  C    sing N N 391 
TRP CA  CB   sing N N 392 
TRP CA  HA   sing N N 393 
TRP C   O    doub N N 394 
TRP C   OXT  sing N N 395 
TRP CB  CG   sing N N 396 
TRP CB  HB2  sing N N 397 
TRP CB  HB3  sing N N 398 
TRP CG  CD1  doub Y N 399 
TRP CG  CD2  sing Y N 400 
TRP CD1 NE1  sing Y N 401 
TRP CD1 HD1  sing N N 402 
TRP CD2 CE2  doub Y N 403 
TRP CD2 CE3  sing Y N 404 
TRP NE1 CE2  sing Y N 405 
TRP NE1 HE1  sing N N 406 
TRP CE2 CZ2  sing Y N 407 
TRP CE3 CZ3  doub Y N 408 
TRP CE3 HE3  sing N N 409 
TRP CZ2 CH2  doub Y N 410 
TRP CZ2 HZ2  sing N N 411 
TRP CZ3 CH2  sing Y N 412 
TRP CZ3 HZ3  sing N N 413 
TRP CH2 HH2  sing N N 414 
TRP OXT HXT  sing N N 415 
TYR N   CA   sing N N 416 
TYR N   H    sing N N 417 
TYR N   H2   sing N N 418 
TYR CA  C    sing N N 419 
TYR CA  CB   sing N N 420 
TYR CA  HA   sing N N 421 
TYR C   O    doub N N 422 
TYR C   OXT  sing N N 423 
TYR CB  CG   sing N N 424 
TYR CB  HB2  sing N N 425 
TYR CB  HB3  sing N N 426 
TYR CG  CD1  doub Y N 427 
TYR CG  CD2  sing Y N 428 
TYR CD1 CE1  sing Y N 429 
TYR CD1 HD1  sing N N 430 
TYR CD2 CE2  doub Y N 431 
TYR CD2 HD2  sing N N 432 
TYR CE1 CZ   doub Y N 433 
TYR CE1 HE1  sing N N 434 
TYR CE2 CZ   sing Y N 435 
TYR CE2 HE2  sing N N 436 
TYR CZ  OH   sing N N 437 
TYR OH  HH   sing N N 438 
TYR OXT HXT  sing N N 439 
VAL N   CA   sing N N 440 
VAL N   H    sing N N 441 
VAL N   H2   sing N N 442 
VAL CA  C    sing N N 443 
VAL CA  CB   sing N N 444 
VAL CA  HA   sing N N 445 
VAL C   O    doub N N 446 
VAL C   OXT  sing N N 447 
VAL CB  CG1  sing N N 448 
VAL CB  CG2  sing N N 449 
VAL CB  HB   sing N N 450 
VAL CG1 HG11 sing N N 451 
VAL CG1 HG12 sing N N 452 
VAL CG1 HG13 sing N N 453 
VAL CG2 HG21 sing N N 454 
VAL CG2 HG22 sing N N 455 
VAL CG2 HG23 sing N N 456 
VAL OXT HXT  sing N N 457 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-05-09 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           8ZGO 
_em_admin.last_update        2025-05-14 
_em_admin.map_release_date   2025-05-14 
_em_admin.title              'CryoEM structure of monomeric quinol dependent nitric oxide reductase from Neisseria meningitidis' 
# 
loop_
_em_buffer_component.buffer_id 
_em_buffer_component.concentration 
_em_buffer_component.concentration_units 
_em_buffer_component.formula 
_em_buffer_component.id 
_em_buffer_component.name 
1 0.15 M NaCl  1 'Sodium Chloride'                                         
1 0.05 M HEPES 2 '2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonic acid' 
1 0.1  % DTM   3 decyl-thio-maltoside                                      
# 
_em_ctf_correction.details                  'Patch based CTF' 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_molwt.entity_assembly_id   1 
_em_entity_assembly_molwt.experimental_flag    NO 
_em_entity_assembly_molwt.id                   1 
_em_entity_assembly_molwt.units                MEGADALTONS 
_em_entity_assembly_molwt.value                0.085 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          662598 
_em_entity_assembly_naturalsource.organism             'Neisseria meningitidis alpha14' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          469008 
_em_entity_assembly_recombinant.organism             'Escherichia coli BL21(DE3)' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               'C41 (DE3)' 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               3.66 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         50 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     8100 
# 
_em_imaging_optics.chr_aberration_corrector   ? 
_em_imaging_optics.energyfilter_lower         ? 
_em_imaging_optics.energyfilter_slit_width    20 
_em_imaging_optics.energyfilter_name          'In-column Omega Filter' 
_em_imaging_optics.energyfilter_upper         ? 
_em_imaging_optics.id                         1 
_em_imaging_optics.imaging_id                 1 
_em_imaging_optics.phase_plate                ? 
_em_imaging_optics.sph_aberration_corrector   ? 
_em_imaging_optics.details                    ? 
# 
_em_particle_selection.details                  'cryoSPARC blob based picking to generate 2D templates for template based picking.' 
_em_particle_selection.id                       1 
_em_particle_selection.image_processing_id      1 
_em_particle_selection.method                   ? 
_em_particle_selection.num_particles_selected   4640985 
_em_particle_selection.reference_model          ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? cryoSPARC       4.1.1 
'IMAGE ACQUISITION'        ? 2  ? ? 1 SerialEM        ?     
MASKING                    ? 3  ? ? ? ?               ?     
'CTF CORRECTION'           ? 4  1 ? ? cryoSPARC       4.1.1 
'LAYERLINE INDEXING'       ? 5  ? ? ? ?               ?     
'DIFFRACTION INDEXING'     ? 6  ? ? ? ?               ?     
'MODEL FITTING'            ? 7  ? 1 ? 'UCSF ChimeraX' 1.4   
OTHER                      ? 8  ? ? ? ?               ?     
'INITIAL EULER ASSIGNMENT' ? 9  1 ? ? cryoSPARC       4.1.1 
'FINAL EULER ASSIGNMENT'   ? 10 1 ? ? cryoSPARC       4.1.1 
CLASSIFICATION             ? 11 1 ? ? cryoSPARC       4.1.1 
RECONSTRUCTION             ? 12 1 ? ? cryoSPARC       4.1.1 
'MODEL REFINEMENT'         ? 13 ? 1 ? PHENIX          1.20  
# 
_em_specimen.concentration           15 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'Japan Society for the Promotion of Science (JSPS)' Japan JP19H05761 1 
'Japan Society for the Promotion of Science (JSPS)' Japan JP20K22633 2 
# 
_atom_sites.entry_id                    8ZGO 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C  
CA 
FE 
N  
O  
S  
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N  N   . MET A 1 1   ? 140.850 102.732 149.475 1.00 130.22 ? 1   MET A N   1 
ATOM   2    C  CA  . MET A 1 1   ? 139.804 103.501 148.813 1.00 135.18 ? 1   MET A CA  1 
ATOM   3    C  C   . MET A 1 1   ? 138.477 102.753 148.852 1.00 136.38 ? 1   MET A C   1 
ATOM   4    O  O   . MET A 1 1   ? 137.423 103.326 148.581 1.00 133.87 ? 1   MET A O   1 
ATOM   5    C  CB  . MET A 1 1   ? 140.198 103.812 147.370 1.00 138.95 ? 1   MET A CB  1 
ATOM   6    C  CG  . MET A 1 1   ? 141.574 104.439 147.237 1.00 140.86 ? 1   MET A CG  1 
ATOM   7    S  SD  . MET A 1 1   ? 142.204 104.421 145.550 1.00 146.35 ? 1   MET A SD  1 
ATOM   8    C  CE  . MET A 1 1   ? 142.913 106.061 145.450 1.00 135.48 ? 1   MET A CE  1 
ATOM   9    N  N   . GLY A 1 2   ? 138.539 101.468 149.191 1.00 138.07 ? 2   GLY A N   1 
ATOM   10   C  CA  . GLY A 1 2   ? 137.344 100.662 149.341 1.00 135.64 ? 2   GLY A CA  1 
ATOM   11   C  C   . GLY A 1 2   ? 136.566 100.465 148.058 1.00 136.06 ? 2   GLY A C   1 
ATOM   12   O  O   . GLY A 1 2   ? 137.120 100.039 147.041 1.00 139.65 ? 2   GLY A O   1 
ATOM   13   N  N   . GLN A 1 3   ? 135.269 100.772 148.097 1.00 118.44 ? 3   GLN A N   1 
ATOM   14   C  CA  . GLN A 1 3   ? 134.401 100.600 146.943 1.00 120.80 ? 3   GLN A CA  1 
ATOM   15   C  C   . GLN A 1 3   ? 134.529 101.722 145.921 1.00 122.79 ? 3   GLN A C   1 
ATOM   16   O  O   . GLN A 1 3   ? 133.941 101.621 144.839 1.00 124.53 ? 3   GLN A O   1 
ATOM   17   C  CB  . GLN A 1 3   ? 132.945 100.483 147.398 1.00 116.86 ? 3   GLN A CB  1 
ATOM   18   C  CG  . GLN A 1 3   ? 132.260 101.818 147.629 1.00 121.25 ? 3   GLN A CG  1 
ATOM   19   C  CD  . GLN A 1 3   ? 131.235 101.761 148.743 1.00 123.12 ? 3   GLN A CD  1 
ATOM   20   O  OE1 . GLN A 1 3   ? 131.571 101.493 149.895 1.00 122.25 ? 3   GLN A OE1 1 
ATOM   21   N  NE2 . GLN A 1 3   ? 129.979 102.017 148.404 1.00 121.46 ? 3   GLN A NE2 1 
ATOM   22   N  N   . TYR A 1 4   ? 135.277 102.781 146.230 1.00 111.00 ? 4   TYR A N   1 
ATOM   23   C  CA  . TYR A 1 4   ? 135.467 103.903 145.321 1.00 109.85 ? 4   TYR A CA  1 
ATOM   24   C  C   . TYR A 1 4   ? 136.775 103.808 144.547 1.00 113.73 ? 4   TYR A C   1 
ATOM   25   O  O   . TYR A 1 4   ? 137.203 104.800 143.944 1.00 116.70 ? 4   TYR A O   1 
ATOM   26   C  CB  . TYR A 1 4   ? 135.406 105.222 146.092 1.00 111.10 ? 4   TYR A CB  1 
ATOM   27   C  CG  . TYR A 1 4   ? 134.304 105.287 147.121 1.00 113.00 ? 4   TYR A CG  1 
ATOM   28   C  CD1 . TYR A 1 4   ? 133.013 105.642 146.763 1.00 111.10 ? 4   TYR A CD1 1 
ATOM   29   C  CD2 . TYR A 1 4   ? 134.557 104.994 148.451 1.00 117.00 ? 4   TYR A CD2 1 
ATOM   30   C  CE1 . TYR A 1 4   ? 132.005 105.703 147.704 1.00 115.44 ? 4   TYR A CE1 1 
ATOM   31   C  CE2 . TYR A 1 4   ? 133.560 105.053 149.397 1.00 117.54 ? 4   TYR A CE2 1 
ATOM   32   C  CZ  . TYR A 1 4   ? 132.287 105.408 149.020 1.00 118.33 ? 4   TYR A CZ  1 
ATOM   33   O  OH  . TYR A 1 4   ? 131.293 105.466 149.966 1.00 114.68 ? 4   TYR A OH  1 
ATOM   34   N  N   . LYS A 1 5   ? 137.419 102.640 144.557 1.00 112.03 ? 5   LYS A N   1 
ATOM   35   C  CA  . LYS A 1 5   ? 138.690 102.479 143.860 1.00 110.13 ? 5   LYS A CA  1 
ATOM   36   C  C   . LYS A 1 5   ? 138.547 102.726 142.365 1.00 110.96 ? 5   LYS A C   1 
ATOM   37   O  O   . LYS A 1 5   ? 139.400 103.389 141.763 1.00 110.33 ? 5   LYS A O   1 
ATOM   38   C  CB  . LYS A 1 5   ? 139.248 101.078 144.112 1.00 109.77 ? 5   LYS A CB  1 
ATOM   39   C  CG  . LYS A 1 5   ? 140.715 100.916 143.764 1.00 111.09 ? 5   LYS A CG  1 
ATOM   40   C  CD  . LYS A 1 5   ? 141.085 99.449  143.634 1.00 112.29 ? 5   LYS A CD  1 
ATOM   41   C  CE  . LYS A 1 5   ? 142.050 99.017  144.725 1.00 113.81 ? 5   LYS A CE  1 
ATOM   42   N  NZ  . LYS A 1 5   ? 143.306 99.814  144.706 1.00 112.98 ? 5   LYS A NZ  1 
ATOM   43   N  N   . LYS A 1 6   ? 137.486 102.205 141.751 1.00 113.39 ? 6   LYS A N   1 
ATOM   44   C  CA  . LYS A 1 6   ? 137.273 102.398 140.321 1.00 112.13 ? 6   LYS A CA  1 
ATOM   45   C  C   . LYS A 1 6   ? 137.075 103.870 139.985 1.00 111.46 ? 6   LYS A C   1 
ATOM   46   O  O   . LYS A 1 6   ? 137.627 104.369 138.998 1.00 117.32 ? 6   LYS A O   1 
ATOM   47   C  CB  . LYS A 1 6   ? 136.074 101.574 139.855 1.00 110.17 ? 6   LYS A CB  1 
ATOM   48   C  CG  . LYS A 1 6   ? 136.273 100.074 139.971 1.00 113.70 ? 6   LYS A CG  1 
ATOM   49   C  CD  . LYS A 1 6   ? 135.594 99.337  138.830 1.00 114.09 ? 6   LYS A CD  1 
ATOM   50   C  CE  . LYS A 1 6   ? 136.127 97.920  138.700 1.00 112.72 ? 6   LYS A CE  1 
ATOM   51   N  NZ  . LYS A 1 6   ? 137.288 97.676  139.602 1.00 108.25 ? 6   LYS A NZ  1 
ATOM   52   N  N   . LEU A 1 7   ? 136.284 104.582 140.792 1.00 100.29 ? 7   LEU A N   1 
ATOM   53   C  CA  . LEU A 1 7   ? 136.071 106.004 140.551 1.00 99.38  ? 7   LEU A CA  1 
ATOM   54   C  C   . LEU A 1 7   ? 137.357 106.803 140.724 1.00 101.53 ? 7   LEU A C   1 
ATOM   55   O  O   . LEU A 1 7   ? 137.642 107.702 139.925 1.00 104.63 ? 7   LEU A O   1 
ATOM   56   C  CB  . LEU A 1 7   ? 134.983 106.535 141.482 1.00 97.59  ? 7   LEU A CB  1 
ATOM   57   C  CG  . LEU A 1 7   ? 133.552 106.123 141.137 1.00 99.92  ? 7   LEU A CG  1 
ATOM   58   C  CD1 . LEU A 1 7   ? 132.637 106.314 142.331 1.00 100.60 ? 7   LEU A CD1 1 
ATOM   59   C  CD2 . LEU A 1 7   ? 133.043 106.902 139.937 1.00 100.53 ? 7   LEU A CD2 1 
ATOM   60   N  N   . TRP A 1 8   ? 138.145 106.487 141.756 1.00 97.78  ? 8   TRP A N   1 
ATOM   61   C  CA  . TRP A 1 8   ? 139.423 107.162 141.948 1.00 96.75  ? 8   TRP A CA  1 
ATOM   62   C  C   . TRP A 1 8   ? 140.356 106.923 140.768 1.00 103.95 ? 8   TRP A C   1 
ATOM   63   O  O   . TRP A 1 8   ? 141.010 107.852 140.284 1.00 103.48 ? 8   TRP A O   1 
ATOM   64   C  CB  . TRP A 1 8   ? 140.080 106.690 143.247 1.00 96.34  ? 8   TRP A CB  1 
ATOM   65   C  CG  . TRP A 1 8   ? 139.594 107.386 144.484 1.00 96.42  ? 8   TRP A CG  1 
ATOM   66   C  CD1 . TRP A 1 8   ? 138.885 106.830 145.508 1.00 102.65 ? 8   TRP A CD1 1 
ATOM   67   C  CD2 . TRP A 1 8   ? 139.790 108.761 144.834 1.00 96.90  ? 8   TRP A CD2 1 
ATOM   68   N  NE1 . TRP A 1 8   ? 138.625 107.772 146.471 1.00 99.14  ? 8   TRP A NE1 1 
ATOM   69   C  CE2 . TRP A 1 8   ? 139.170 108.967 146.081 1.00 97.34  ? 8   TRP A CE2 1 
ATOM   70   C  CE3 . TRP A 1 8   ? 140.428 109.839 144.213 1.00 102.09 ? 8   TRP A CE3 1 
ATOM   71   C  CZ2 . TRP A 1 8   ? 139.167 110.204 146.717 1.00 98.80  ? 8   TRP A CZ2 1 
ATOM   72   C  CZ3 . TRP A 1 8   ? 140.424 111.067 144.847 1.00 103.46 ? 8   TRP A CZ3 1 
ATOM   73   C  CH2 . TRP A 1 8   ? 139.797 111.238 146.086 1.00 102.46 ? 8   TRP A CH2 1 
ATOM   74   N  N   . TYR A 1 9   ? 140.426 105.678 140.289 1.00 110.05 ? 9   TYR A N   1 
ATOM   75   C  CA  . TYR A 1 9   ? 141.296 105.360 139.160 1.00 103.28 ? 9   TYR A CA  1 
ATOM   76   C  C   . TYR A 1 9   ? 140.829 106.052 137.887 1.00 104.83 ? 9   TYR A C   1 
ATOM   77   O  O   . TYR A 1 9   ? 141.648 106.526 137.092 1.00 111.60 ? 9   TYR A O   1 
ATOM   78   C  CB  . TYR A 1 9   ? 141.358 103.846 138.956 1.00 103.51 ? 9   TYR A CB  1 
ATOM   79   C  CG  . TYR A 1 9   ? 142.247 103.129 139.947 1.00 109.16 ? 9   TYR A CG  1 
ATOM   80   C  CD1 . TYR A 1 9   ? 142.455 101.760 139.853 1.00 108.57 ? 9   TYR A CD1 1 
ATOM   81   C  CD2 . TYR A 1 9   ? 142.879 103.818 140.972 1.00 110.48 ? 9   TYR A CD2 1 
ATOM   82   C  CE1 . TYR A 1 9   ? 143.266 101.099 140.753 1.00 109.68 ? 9   TYR A CE1 1 
ATOM   83   C  CE2 . TYR A 1 9   ? 143.691 103.167 141.876 1.00 111.56 ? 9   TYR A CE2 1 
ATOM   84   C  CZ  . TYR A 1 9   ? 143.881 101.808 141.763 1.00 113.03 ? 9   TYR A CZ  1 
ATOM   85   O  OH  . TYR A 1 9   ? 144.690 101.152 142.663 1.00 112.07 ? 9   TYR A OH  1 
ATOM   86   N  N   . LEU A 1 10  ? 139.514 106.109 137.668 1.00 95.40  ? 10  LEU A N   1 
ATOM   87   C  CA  . LEU A 1 10  ? 138.993 106.809 136.500 1.00 96.51  ? 10  LEU A CA  1 
ATOM   88   C  C   . LEU A 1 10  ? 139.324 108.293 136.559 1.00 97.52  ? 10  LEU A C   1 
ATOM   89   O  O   . LEU A 1 10  ? 139.713 108.891 135.547 1.00 101.03 ? 10  LEU A O   1 
ATOM   90   C  CB  . LEU A 1 10  ? 137.483 106.599 136.390 1.00 95.12  ? 10  LEU A CB  1 
ATOM   91   C  CG  . LEU A 1 10  ? 136.727 107.579 135.493 1.00 95.16  ? 10  LEU A CG  1 
ATOM   92   C  CD1 . LEU A 1 10  ? 136.800 107.138 134.041 1.00 101.50 ? 10  LEU A CD1 1 
ATOM   93   C  CD2 . LEU A 1 10  ? 135.283 107.714 135.942 1.00 91.21  ? 10  LEU A CD2 1 
ATOM   94   N  N   . LEU A 1 11  ? 139.183 108.904 137.738 1.00 90.47  ? 11  LEU A N   1 
ATOM   95   C  CA  . LEU A 1 11  ? 139.549 110.308 137.885 1.00 89.08  ? 11  LEU A CA  1 
ATOM   96   C  C   . LEU A 1 11  ? 141.036 110.520 137.629 1.00 91.41  ? 11  LEU A C   1 
ATOM   97   O  O   . LEU A 1 11  ? 141.426 111.483 136.957 1.00 99.58  ? 11  LEU A O   1 
ATOM   98   C  CB  . LEU A 1 11  ? 139.162 110.805 139.277 1.00 85.26  ? 11  LEU A CB  1 
ATOM   99   C  CG  . LEU A 1 11  ? 139.671 112.186 139.692 1.00 85.81  ? 11  LEU A CG  1 
ATOM   100  C  CD1 . LEU A 1 11  ? 139.058 113.273 138.830 1.00 87.43  ? 11  LEU A CD1 1 
ATOM   101  C  CD2 . LEU A 1 11  ? 139.373 112.440 141.158 1.00 89.61  ? 11  LEU A CD2 1 
ATOM   102  N  N   . PHE A 1 12  ? 141.881 109.626 138.149 1.00 90.38  ? 12  PHE A N   1 
ATOM   103  C  CA  . PHE A 1 12  ? 143.318 109.742 137.926 1.00 89.08  ? 12  PHE A CA  1 
ATOM   104  C  C   . PHE A 1 12  ? 143.656 109.644 136.444 1.00 92.50  ? 12  PHE A C   1 
ATOM   105  O  O   . PHE A 1 12  ? 144.462 110.426 135.926 1.00 100.09 ? 12  PHE A O   1 
ATOM   106  C  CB  . PHE A 1 12  ? 144.063 108.661 138.711 1.00 92.90  ? 12  PHE A CB  1 
ATOM   107  C  CG  . PHE A 1 12  ? 143.958 108.805 140.200 1.00 98.54  ? 12  PHE A CG  1 
ATOM   108  C  CD1 . PHE A 1 12  ? 143.735 110.042 140.777 1.00 95.94  ? 12  PHE A CD1 1 
ATOM   109  C  CD2 . PHE A 1 12  ? 144.088 107.701 141.024 1.00 100.82 ? 12  PHE A CD2 1 
ATOM   110  C  CE1 . PHE A 1 12  ? 143.640 110.175 142.146 1.00 97.88  ? 12  PHE A CE1 1 
ATOM   111  C  CE2 . PHE A 1 12  ? 143.992 107.827 142.394 1.00 99.56  ? 12  PHE A CE2 1 
ATOM   112  C  CZ  . PHE A 1 12  ? 143.768 109.064 142.956 1.00 101.51 ? 12  PHE A CZ  1 
ATOM   113  N  N   . ALA A 1 13  ? 143.051 108.680 135.747 1.00 89.20  ? 13  ALA A N   1 
ATOM   114  C  CA  . ALA A 1 13  ? 143.331 108.505 134.325 1.00 87.32  ? 13  ALA A CA  1 
ATOM   115  C  C   . ALA A 1 13  ? 142.860 109.706 133.516 1.00 88.90  ? 13  ALA A C   1 
ATOM   116  O  O   . ALA A 1 13  ? 143.567 110.173 132.614 1.00 94.87  ? 13  ALA A O   1 
ATOM   117  C  CB  . ALA A 1 13  ? 142.674 107.224 133.815 1.00 85.83  ? 13  ALA A CB  1 
ATOM   118  N  N   . VAL A 1 14  ? 141.667 110.221 133.826 1.00 81.05  ? 14  VAL A N   1 
ATOM   119  C  CA  . VAL A 1 14  ? 141.156 111.392 133.121 1.00 81.81  ? 14  VAL A CA  1 
ATOM   120  C  C   . VAL A 1 14  ? 142.081 112.582 133.341 1.00 85.70  ? 14  VAL A C   1 
ATOM   121  O  O   . VAL A 1 14  ? 142.432 113.300 132.396 1.00 96.61  ? 14  VAL A O   1 
ATOM   122  C  CB  . VAL A 1 14  ? 139.717 111.703 133.570 1.00 83.58  ? 14  VAL A CB  1 
ATOM   123  C  CG1 . VAL A 1 14  ? 139.379 113.161 133.316 1.00 77.05  ? 14  VAL A CG1 1 
ATOM   124  C  CG2 . VAL A 1 14  ? 138.734 110.793 132.859 1.00 87.32  ? 14  VAL A CG2 1 
ATOM   125  N  N   . LEU A 1 15  ? 142.497 112.797 134.591 1.00 83.28  ? 15  LEU A N   1 
ATOM   126  C  CA  . LEU A 1 15  ? 143.398 113.902 134.899 1.00 82.02  ? 15  LEU A CA  1 
ATOM   127  C  C   . LEU A 1 15  ? 144.705 113.771 134.132 1.00 86.89  ? 15  LEU A C   1 
ATOM   128  O  O   . LEU A 1 15  ? 145.173 114.732 133.509 1.00 90.82  ? 15  LEU A O   1 
ATOM   129  C  CB  . LEU A 1 15  ? 143.660 113.945 136.404 1.00 77.72  ? 15  LEU A CB  1 
ATOM   130  C  CG  . LEU A 1 15  ? 142.754 114.837 137.250 1.00 80.37  ? 15  LEU A CG  1 
ATOM   131  C  CD1 . LEU A 1 15  ? 143.240 114.866 138.686 1.00 84.49  ? 15  LEU A CD1 1 
ATOM   132  C  CD2 . LEU A 1 15  ? 142.701 116.237 136.677 1.00 82.11  ? 15  LEU A CD2 1 
ATOM   133  N  N   . ALA A 1 16  ? 145.298 112.575 134.150 1.00 87.97  ? 16  ALA A N   1 
ATOM   134  C  CA  . ALA A 1 16  ? 146.574 112.364 133.479 1.00 84.70  ? 16  ALA A CA  1 
ATOM   135  C  C   . ALA A 1 16  ? 146.459 112.620 131.983 1.00 85.38  ? 16  ALA A C   1 
ATOM   136  O  O   . ALA A 1 16  ? 147.271 113.351 131.406 1.00 93.05  ? 16  ALA A O   1 
ATOM   137  C  CB  . ALA A 1 16  ? 147.077 110.946 133.745 1.00 84.83  ? 16  ALA A CB  1 
ATOM   138  N  N   . VAL A 1 17  ? 145.442 112.041 131.340 1.00 80.93  ? 17  VAL A N   1 
ATOM   139  C  CA  . VAL A 1 17  ? 145.309 112.177 129.890 1.00 84.44  ? 17  VAL A CA  1 
ATOM   140  C  C   . VAL A 1 17  ? 145.048 113.631 129.512 1.00 90.47  ? 17  VAL A C   1 
ATOM   141  O  O   . VAL A 1 17  ? 145.684 114.180 128.600 1.00 99.05  ? 17  VAL A O   1 
ATOM   142  C  CB  . VAL A 1 17  ? 144.199 111.248 129.367 1.00 85.72  ? 17  VAL A CB  1 
ATOM   143  C  CG1 . VAL A 1 17  ? 143.703 111.714 128.009 1.00 82.53  ? 17  VAL A CG1 1 
ATOM   144  C  CG2 . VAL A 1 17  ? 144.701 109.817 129.293 1.00 90.95  ? 17  VAL A CG2 1 
ATOM   145  N  N   . CYS A 1 18  ? 144.165 114.292 130.235 1.00 90.48  ? 18  CYS A N   1 
ATOM   146  C  CA  . CYS A 1 18  ? 143.763 115.663 129.855 1.00 84.49  ? 18  CYS A CA  1 
ATOM   147  C  C   . CYS A 1 18  ? 144.897 116.658 130.113 1.00 89.86  ? 18  CYS A C   1 
ATOM   148  O  O   . CYS A 1 18  ? 145.108 117.555 129.281 1.00 100.84 ? 18  CYS A O   1 
ATOM   149  C  CB  . CYS A 1 18  ? 142.455 116.029 130.544 1.00 83.87  ? 18  CYS A CB  1 
ATOM   150  S  SG  . CYS A 1 18  ? 141.038 115.112 129.887 1.00 104.38 ? 18  CYS A SG  1 
ATOM   151  N  N   . PHE A 1 19  ? 145.651 116.536 131.182 1.00 77.72  ? 19  PHE A N   1 
ATOM   152  C  CA  . PHE A 1 19  ? 146.812 117.438 131.380 1.00 76.61  ? 19  PHE A CA  1 
ATOM   153  C  C   . PHE A 1 19  ? 147.967 117.073 130.458 1.00 81.70  ? 19  PHE A C   1 
ATOM   154  O  O   . PHE A 1 19  ? 148.726 117.949 130.149 1.00 90.33  ? 19  PHE A O   1 
ATOM   155  C  CB  . PHE A 1 19  ? 147.203 117.555 132.857 1.00 77.19  ? 19  PHE A CB  1 
ATOM   156  C  CG  . PHE A 1 19  ? 146.353 118.517 133.648 1.00 82.73  ? 19  PHE A CG  1 
ATOM   157  C  CD1 . PHE A 1 19  ? 146.507 119.889 133.514 1.00 79.84  ? 19  PHE A CD1 1 
ATOM   158  C  CD2 . PHE A 1 19  ? 145.374 118.047 134.507 1.00 86.59  ? 19  PHE A CD2 1 
ATOM   159  C  CE1 . PHE A 1 19  ? 145.714 120.765 134.237 1.00 81.96  ? 19  PHE A CE1 1 
ATOM   160  C  CE2 . PHE A 1 19  ? 144.585 118.924 135.231 1.00 81.29  ? 19  PHE A CE2 1 
ATOM   161  C  CZ  . PHE A 1 19  ? 144.752 120.281 135.089 1.00 82.37  ? 19  PHE A CZ  1 
ATOM   162  N  N   . THR A 1 20  ? 148.125 115.803 130.122 1.00 86.79  ? 20  THR A N   1 
ATOM   163  C  CA  . THR A 1 20  ? 149.140 115.502 129.121 1.00 87.87  ? 20  THR A CA  1 
ATOM   164  C  C   . THR A 1 20  ? 148.819 116.179 127.796 1.00 85.60  ? 20  THR A C   1 
ATOM   165  O  O   . THR A 1 20  ? 149.703 116.760 127.157 1.00 94.38  ? 20  THR A O   1 
ATOM   166  C  CB  . THR A 1 20  ? 149.267 113.990 128.934 1.00 90.14  ? 20  THR A CB  1 
ATOM   167  O  OG1 . THR A 1 20  ? 149.570 113.377 130.192 1.00 101.66 ? 20  THR A OG1 1 
ATOM   168  C  CG2 . THR A 1 20  ? 150.367 113.665 127.939 1.00 88.25  ? 20  THR A CG2 1 
ATOM   169  N  N   . ILE A 1 21  ? 147.552 116.130 127.376 1.00 74.76  ? 21  ILE A N   1 
ATOM   170  C  CA  . ILE A 1 21  ? 147.159 116.793 126.132 1.00 76.43  ? 21  ILE A CA  1 
ATOM   171  C  C   . ILE A 1 21  ? 147.378 118.297 126.236 1.00 76.72  ? 21  ILE A C   1 
ATOM   172  O  O   . ILE A 1 21  ? 147.965 118.923 125.341 1.00 86.00  ? 21  ILE A O   1 
ATOM   173  C  CB  . ILE A 1 21  ? 145.698 116.457 125.786 1.00 74.22  ? 21  ILE A CB  1 
ATOM   174  C  CG1 . ILE A 1 21  ? 145.575 115.001 125.338 1.00 78.91  ? 21  ILE A CG1 1 
ATOM   175  C  CG2 . ILE A 1 21  ? 145.174 117.392 124.709 1.00 68.21  ? 21  ILE A CG2 1 
ATOM   176  C  CD1 . ILE A 1 21  ? 144.150 114.500 125.301 1.00 78.60  ? 21  ILE A CD1 1 
ATOM   177  N  N   . LEU A 1 22  ? 146.929 118.901 127.340 1.00 71.49  ? 22  LEU A N   1 
ATOM   178  C  CA  . LEU A 1 22  ? 147.062 120.343 127.507 1.00 69.75  ? 22  LEU A CA  1 
ATOM   179  C  C   . LEU A 1 22  ? 148.524 120.773 127.577 1.00 76.63  ? 22  LEU A C   1 
ATOM   180  O  O   . LEU A 1 22  ? 148.894 121.807 127.010 1.00 86.52  ? 22  LEU A O   1 
ATOM   181  C  CB  . LEU A 1 22  ? 146.306 120.796 128.757 1.00 76.23  ? 22  LEU A CB  1 
ATOM   182  C  CG  . LEU A 1 22  ? 146.165 122.303 128.976 1.00 74.12  ? 22  LEU A CG  1 
ATOM   183  C  CD1 . LEU A 1 22  ? 145.437 122.943 127.808 1.00 77.25  ? 22  LEU A CD1 1 
ATOM   184  C  CD2 . LEU A 1 22  ? 145.426 122.578 130.270 1.00 76.69  ? 22  LEU A CD2 1 
ATOM   185  N  N   . GLY A 1 23  ? 149.367 120.001 128.268 1.00 87.35  ? 23  GLY A N   1 
ATOM   186  C  CA  . GLY A 1 23  ? 150.783 120.313 128.316 1.00 88.02  ? 23  GLY A CA  1 
ATOM   187  C  C   . GLY A 1 23  ? 151.478 120.144 126.983 1.00 88.73  ? 23  GLY A C   1 
ATOM   188  O  O   . GLY A 1 23  ? 152.366 120.931 126.641 1.00 93.12  ? 23  GLY A O   1 
ATOM   189  N  N   . TYR A 1 24  ? 151.103 119.117 126.216 1.00 89.37  ? 24  TYR A N   1 
ATOM   190  C  CA  . TYR A 1 24  ? 151.678 118.949 124.887 1.00 87.99  ? 24  TYR A CA  1 
ATOM   191  C  C   . TYR A 1 24  ? 151.319 120.124 123.991 1.00 88.69  ? 24  TYR A C   1 
ATOM   192  O  O   . TYR A 1 24  ? 152.157 120.612 123.225 1.00 95.86  ? 24  TYR A O   1 
ATOM   193  C  CB  . TYR A 1 24  ? 151.205 117.640 124.258 1.00 92.07  ? 24  TYR A CB  1 
ATOM   194  C  CG  . TYR A 1 24  ? 151.339 117.635 122.753 1.00 92.64  ? 24  TYR A CG  1 
ATOM   195  C  CD1 . TYR A 1 24  ? 152.577 117.462 122.151 1.00 94.74  ? 24  TYR A CD1 1 
ATOM   196  C  CD2 . TYR A 1 24  ? 150.232 117.819 121.934 1.00 92.93  ? 24  TYR A CD2 1 
ATOM   197  C  CE1 . TYR A 1 24  ? 152.708 117.466 120.777 1.00 98.52  ? 24  TYR A CE1 1 
ATOM   198  C  CE2 . TYR A 1 24  ? 150.354 117.826 120.561 1.00 97.78  ? 24  TYR A CE2 1 
ATOM   199  C  CZ  . TYR A 1 24  ? 151.595 117.649 119.987 1.00 104.15 ? 24  TYR A CZ  1 
ATOM   200  O  OH  . TYR A 1 24  ? 151.720 117.650 118.619 1.00 103.70 ? 24  TYR A OH  1 
ATOM   201  N  N   . MET A 1 25  ? 150.071 120.592 124.065 1.00 93.87  ? 25  MET A N   1 
ATOM   202  C  CA  . MET A 1 25  ? 149.701 121.746 123.255 1.00 93.46  ? 25  MET A CA  1 
ATOM   203  C  C   . MET A 1 25  ? 150.388 123.013 123.742 1.00 91.98  ? 25  MET A C   1 
ATOM   204  O  O   . MET A 1 25  ? 150.554 123.963 122.969 1.00 98.16  ? 25  MET A O   1 
ATOM   205  C  CB  . MET A 1 25  ? 148.187 121.933 123.246 1.00 95.49  ? 25  MET A CB  1 
ATOM   206  C  CG  . MET A 1 25  ? 147.493 121.086 122.203 1.00 102.65 ? 25  MET A CG  1 
ATOM   207  S  SD  . MET A 1 25  ? 147.956 121.585 120.536 1.00 123.99 ? 25  MET A SD  1 
ATOM   208  C  CE  . MET A 1 25  ? 147.169 123.183 120.423 1.00 99.94  ? 25  MET A CE  1 
ATOM   209  N  N   . GLY A 1 26  ? 150.775 123.057 125.018 1.00 82.25  ? 26  GLY A N   1 
ATOM   210  C  CA  . GLY A 1 26  ? 151.529 124.197 125.510 1.00 82.86  ? 26  GLY A CA  1 
ATOM   211  C  C   . GLY A 1 26  ? 152.912 124.293 124.898 1.00 86.84  ? 26  GLY A C   1 
ATOM   212  O  O   . GLY A 1 26  ? 153.360 125.378 124.519 1.00 95.87  ? 26  GLY A O   1 
ATOM   213  N  N   . SER A 1 27  ? 153.610 123.161 124.798 1.00 83.11  ? 27  SER A N   1 
ATOM   214  C  CA  . SER A 1 27  ? 154.912 123.142 124.145 1.00 87.17  ? 27  SER A CA  1 
ATOM   215  C  C   . SER A 1 27  ? 154.808 123.433 122.658 1.00 87.50  ? 27  SER A C   1 
ATOM   216  O  O   . SER A 1 27  ? 155.759 123.962 122.073 1.00 85.85  ? 27  SER A O   1 
ATOM   217  C  CB  . SER A 1 27  ? 155.589 121.790 124.370 1.00 85.95  ? 27  SER A CB  1 
ATOM   218  O  OG  . SER A 1 27  ? 155.423 120.948 123.244 1.00 87.59  ? 27  SER A OG  1 
ATOM   219  N  N   . GLU A 1 28  ? 153.678 123.098 122.034 1.00 99.57  ? 28  GLU A N   1 
ATOM   220  C  CA  . GLU A 1 28  ? 153.473 123.417 120.629 1.00 98.43  ? 28  GLU A CA  1 
ATOM   221  C  C   . GLU A 1 28  ? 153.325 124.915 120.405 1.00 101.04 ? 28  GLU A C   1 
ATOM   222  O  O   . GLU A 1 28  ? 153.750 125.425 119.363 1.00 103.18 ? 28  GLU A O   1 
ATOM   223  C  CB  . GLU A 1 28  ? 152.245 122.677 120.101 1.00 100.96 ? 28  GLU A CB  1 
ATOM   224  C  CG  . GLU A 1 28  ? 152.193 122.551 118.589 1.00 106.51 ? 28  GLU A CG  1 
ATOM   225  C  CD  . GLU A 1 28  ? 152.960 121.347 118.075 1.00 113.65 ? 28  GLU A CD  1 
ATOM   226  O  OE1 . GLU A 1 28  ? 153.749 120.763 118.847 1.00 114.18 ? 28  GLU A OE1 1 
ATOM   227  O  OE2 . GLU A 1 28  ? 152.776 120.988 116.894 1.00 112.81 ? 28  GLU A OE2 1 
ATOM   228  N  N   . VAL A 1 29  ? 152.720 125.644 121.320 1.00 86.90  ? 29  VAL A N   1 
ATOM   229  C  CA  . VAL A 1 29  ? 152.542 127.110 121.250 1.00 81.10  ? 29  VAL A CA  1 
ATOM   230  C  C   . VAL A 1 29  ? 153.881 127.846 121.361 1.00 84.90  ? 29  VAL A C   1 
ATOM   231  O  O   . VAL A 1 29  ? 153.992 128.894 120.793 1.00 96.12  ? 29  VAL A O   1 
ATOM   232  C  CB  . VAL A 1 29  ? 151.559 127.519 122.363 1.00 72.79  ? 29  VAL A CB  1 
ATOM   233  C  CG1 . VAL A 1 29  ? 151.607 129.005 122.705 1.00 73.47  ? 29  VAL A CG1 1 
ATOM   234  C  CG2 . VAL A 1 29  ? 150.131 127.092 122.058 1.00 78.62  ? 29  VAL A CG2 1 
ATOM   235  N  N   . TYR A 1 30  ? 154.841 127.327 122.125 1.00 79.97  ? 30  TYR A N   1 
ATOM   236  C  CA  . TYR A 1 30  ? 156.163 127.939 122.218 1.00 83.13  ? 30  TYR A CA  1 
ATOM   237  C  C   . TYR A 1 30  ? 156.943 127.811 120.918 1.00 92.81  ? 30  TYR A C   1 
ATOM   238  O  O   . TYR A 1 30  ? 157.691 128.724 120.551 1.00 93.15  ? 30  TYR A O   1 
ATOM   239  C  CB  . TYR A 1 30  ? 156.957 127.303 123.360 1.00 82.58  ? 30  TYR A CB  1 
ATOM   240  C  CG  . TYR A 1 30  ? 156.696 127.903 124.720 1.00 85.22  ? 30  TYR A CG  1 
ATOM   241  C  CD1 . TYR A 1 30  ? 155.642 127.459 125.507 1.00 89.01  ? 30  TYR A CD1 1 
ATOM   242  C  CD2 . TYR A 1 30  ? 157.509 128.906 125.224 1.00 86.41  ? 30  TYR A CD2 1 
ATOM   243  C  CE1 . TYR A 1 30  ? 155.404 128.002 126.754 1.00 83.07  ? 30  TYR A CE1 1 
ATOM   244  C  CE2 . TYR A 1 30  ? 157.280 129.454 126.468 1.00 88.32  ? 30  TYR A CE2 1 
ATOM   245  C  CZ  . TYR A 1 30  ? 156.226 128.997 127.228 1.00 86.36  ? 30  TYR A CZ  1 
ATOM   246  O  OH  . TYR A 1 30  ? 155.995 129.541 128.470 1.00 83.66  ? 30  TYR A OH  1 
ATOM   247  N  N   . LYS A 1 31  ? 156.786 126.694 120.208 1.00 98.83  ? 31  LYS A N   1 
ATOM   248  C  CA  . LYS A 1 31  ? 157.554 126.439 118.998 1.00 89.67  ? 31  LYS A CA  1 
ATOM   249  C  C   . LYS A 1 31  ? 156.846 126.874 117.722 1.00 91.79  ? 31  LYS A C   1 
ATOM   250  O  O   . LYS A 1 31  ? 157.514 127.065 116.702 1.00 101.25 ? 31  LYS A O   1 
ATOM   251  C  CB  . LYS A 1 31  ? 157.897 124.949 118.892 1.00 92.11  ? 31  LYS A CB  1 
ATOM   252  C  CG  . LYS A 1 31  ? 159.061 124.520 119.763 1.00 99.39  ? 31  LYS A CG  1 
ATOM   253  C  CD  . LYS A 1 31  ? 158.734 123.259 120.541 1.00 101.70 ? 31  LYS A CD  1 
ATOM   254  C  CE  . LYS A 1 31  ? 158.711 122.042 119.635 1.00 101.87 ? 31  LYS A CE  1 
ATOM   255  N  NZ  . LYS A 1 31  ? 158.807 120.775 120.410 1.00 101.41 ? 31  LYS A NZ  1 
ATOM   256  N  N   . LYS A 1 32  ? 155.526 127.037 117.752 1.00 85.37  ? 32  LYS A N   1 
ATOM   257  C  CA  . LYS A 1 32  ? 154.757 127.330 116.552 1.00 84.45  ? 32  LYS A CA  1 
ATOM   258  C  C   . LYS A 1 32  ? 154.057 128.679 116.595 1.00 87.71  ? 32  LYS A C   1 
ATOM   259  O  O   . LYS A 1 32  ? 153.289 128.987 115.678 1.00 95.86  ? 32  LYS A O   1 
ATOM   260  C  CB  . LYS A 1 32  ? 153.727 126.222 116.309 1.00 88.78  ? 32  LYS A CB  1 
ATOM   261  C  CG  . LYS A 1 32  ? 154.073 125.303 115.155 1.00 93.46  ? 32  LYS A CG  1 
ATOM   262  C  CD  . LYS A 1 32  ? 155.268 124.433 115.488 1.00 92.10  ? 32  LYS A CD  1 
ATOM   263  C  CE  . LYS A 1 32  ? 155.380 123.260 114.532 1.00 91.01  ? 32  LYS A CE  1 
ATOM   264  N  NZ  . LYS A 1 32  ? 154.154 122.419 114.543 1.00 92.76  ? 32  LYS A NZ  1 
ATOM   265  N  N   . ALA A 1 33  ? 154.292 129.488 117.624 1.00 81.25  ? 33  ALA A N   1 
ATOM   266  C  CA  . ALA A 1 33  ? 153.704 130.814 117.664 1.00 81.62  ? 33  ALA A CA  1 
ATOM   267  C  C   . ALA A 1 33  ? 154.288 131.685 116.553 1.00 86.28  ? 33  ALA A C   1 
ATOM   268  O  O   . ALA A 1 33  ? 155.421 131.469 116.118 1.00 86.08  ? 33  ALA A O   1 
ATOM   269  C  CB  . ALA A 1 33  ? 153.954 131.466 119.020 1.00 81.05  ? 33  ALA A CB  1 
ATOM   270  N  N   . PRO A 1 34  ? 153.525 132.659 116.062 1.00 85.32  ? 34  PRO A N   1 
ATOM   271  C  CA  . PRO A 1 34  ? 154.055 133.576 115.047 1.00 80.03  ? 34  PRO A CA  1 
ATOM   272  C  C   . PRO A 1 34  ? 155.261 134.329 115.576 1.00 79.79  ? 34  PRO A C   1 
ATOM   273  O  O   . PRO A 1 34  ? 155.158 135.078 116.559 1.00 84.44  ? 34  PRO A O   1 
ATOM   274  C  CB  . PRO A 1 34  ? 152.877 134.528 114.775 1.00 78.55  ? 34  PRO A CB  1 
ATOM   275  C  CG  . PRO A 1 34  ? 151.960 134.357 115.939 1.00 77.88  ? 34  PRO A CG  1 
ATOM   276  C  CD  . PRO A 1 34  ? 152.114 132.937 116.369 1.00 81.17  ? 34  PRO A CD  1 
ATOM   277  N  N   . PRO A 1 35  ? 156.424 134.148 114.960 1.00 73.63  ? 35  PRO A N   1 
ATOM   278  C  CA  . PRO A 1 35  ? 157.641 134.763 115.488 1.00 75.72  ? 35  PRO A CA  1 
ATOM   279  C  C   . PRO A 1 35  ? 157.649 136.269 115.288 1.00 77.77  ? 35  PRO A C   1 
ATOM   280  O  O   . PRO A 1 35  ? 157.004 136.815 114.393 1.00 83.02  ? 35  PRO A O   1 
ATOM   281  C  CB  . PRO A 1 35  ? 158.754 134.095 114.676 1.00 78.62  ? 35  PRO A CB  1 
ATOM   282  C  CG  . PRO A 1 35  ? 158.103 133.741 113.388 1.00 78.89  ? 35  PRO A CG  1 
ATOM   283  C  CD  . PRO A 1 35  ? 156.668 133.419 113.704 1.00 76.40  ? 35  PRO A CD  1 
ATOM   284  N  N   . TYR A 1 36  ? 158.396 136.941 116.152 1.00 76.97  ? 36  TYR A N   1 
ATOM   285  C  CA  . TYR A 1 36  ? 158.683 138.352 115.950 1.00 75.27  ? 36  TYR A CA  1 
ATOM   286  C  C   . TYR A 1 36  ? 159.865 138.471 114.999 1.00 80.06  ? 36  TYR A C   1 
ATOM   287  O  O   . TYR A 1 36  ? 160.974 138.059 115.355 1.00 91.45  ? 36  TYR A O   1 
ATOM   288  C  CB  . TYR A 1 36  ? 159.007 139.036 117.270 1.00 76.74  ? 36  TYR A CB  1 
ATOM   289  C  CG  . TYR A 1 36  ? 157.865 139.087 118.257 1.00 76.76  ? 36  TYR A CG  1 
ATOM   290  C  CD1 . TYR A 1 36  ? 157.524 137.975 119.014 1.00 74.45  ? 36  TYR A CD1 1 
ATOM   291  C  CD2 . TYR A 1 36  ? 157.137 140.252 118.444 1.00 81.58  ? 36  TYR A CD2 1 
ATOM   292  C  CE1 . TYR A 1 36  ? 156.484 138.021 119.919 1.00 75.63  ? 36  TYR A CE1 1 
ATOM   293  C  CE2 . TYR A 1 36  ? 156.097 140.308 119.348 1.00 76.30  ? 36  TYR A CE2 1 
ATOM   294  C  CZ  . TYR A 1 36  ? 155.774 139.189 120.083 1.00 72.50  ? 36  TYR A CZ  1 
ATOM   295  O  OH  . TYR A 1 36  ? 154.737 139.239 120.986 1.00 78.61  ? 36  TYR A OH  1 
ATOM   296  N  N   . PRO A 1 37  ? 159.680 139.003 113.792 1.00 78.12  ? 37  PRO A N   1 
ATOM   297  C  CA  . PRO A 1 37  ? 160.799 139.073 112.847 1.00 85.43  ? 37  PRO A CA  1 
ATOM   298  C  C   . PRO A 1 37  ? 161.918 139.951 113.380 1.00 87.01  ? 37  PRO A C   1 
ATOM   299  O  O   . PRO A 1 37  ? 161.680 140.972 114.027 1.00 92.23  ? 37  PRO A O   1 
ATOM   300  C  CB  . PRO A 1 37  ? 160.163 139.666 111.585 1.00 87.18  ? 37  PRO A CB  1 
ATOM   301  C  CG  . PRO A 1 37  ? 158.921 140.338 112.057 1.00 83.55  ? 37  PRO A CG  1 
ATOM   302  C  CD  . PRO A 1 37  ? 158.435 139.541 113.222 1.00 75.99  ? 37  PRO A CD  1 
ATOM   303  N  N   . GLU A 1 38  ? 163.157 139.535 113.106 1.00 98.28  ? 38  GLU A N   1 
ATOM   304  C  CA  . GLU A 1 38  ? 164.306 140.336 113.511 1.00 96.52  ? 38  GLU A CA  1 
ATOM   305  C  C   . GLU A 1 38  ? 164.308 141.689 112.814 1.00 103.32 ? 38  GLU A C   1 
ATOM   306  O  O   . GLU A 1 38  ? 164.701 142.693 113.413 1.00 107.32 ? 38  GLU A O   1 
ATOM   307  C  CB  . GLU A 1 38  ? 165.603 139.585 113.214 1.00 99.20  ? 38  GLU A CB  1 
ATOM   308  C  CG  . GLU A 1 38  ? 165.687 138.219 113.866 1.00 106.28 ? 38  GLU A CG  1 
ATOM   309  C  CD  . GLU A 1 38  ? 165.657 138.293 115.378 1.00 111.03 ? 38  GLU A CD  1 
ATOM   310  O  OE1 . GLU A 1 38  ? 166.327 139.182 115.943 1.00 108.89 ? 38  GLU A OE1 1 
ATOM   311  O  OE2 . GLU A 1 38  ? 164.963 137.465 116.002 1.00 113.80 ? 38  GLU A OE2 1 
ATOM   312  N  N   . GLN A 1 39  ? 163.868 141.730 111.560 1.00 104.79 ? 39  GLN A N   1 
ATOM   313  C  CA  . GLN A 1 39  ? 163.811 142.970 110.803 1.00 103.99 ? 39  GLN A CA  1 
ATOM   314  C  C   . GLN A 1 39  ? 162.660 142.883 109.813 1.00 103.58 ? 39  GLN A C   1 
ATOM   315  O  O   . GLN A 1 39  ? 162.361 141.814 109.277 1.00 107.80 ? 39  GLN A O   1 
ATOM   316  C  CB  . GLN A 1 39  ? 165.128 143.238 110.070 1.00 104.31 ? 39  GLN A CB  1 
ATOM   317  C  CG  . GLN A 1 39  ? 166.119 144.076 110.848 1.00 108.47 ? 39  GLN A CG  1 
ATOM   318  C  CD  . GLN A 1 39  ? 167.399 144.310 110.076 1.00 112.73 ? 39  GLN A CD  1 
ATOM   319  O  OE1 . GLN A 1 39  ? 167.640 143.681 109.047 1.00 110.80 ? 39  GLN A OE1 1 
ATOM   320  N  NE2 . GLN A 1 39  ? 168.230 145.220 110.571 1.00 113.93 ? 39  GLN A NE2 1 
ATOM   321  N  N   . VAL A 1 40  ? 162.023 144.021 109.581 1.00 98.27  ? 40  VAL A N   1 
ATOM   322  C  CA  . VAL A 1 40  ? 161.037 144.171 108.517 1.00 97.34  ? 40  VAL A CA  1 
ATOM   323  C  C   . VAL A 1 40  ? 161.649 145.146 107.519 1.00 102.36 ? 40  VAL A C   1 
ATOM   324  O  O   . VAL A 1 40  ? 161.707 146.354 107.755 1.00 108.31 ? 40  VAL A O   1 
ATOM   325  C  CB  . VAL A 1 40  ? 159.681 144.660 109.029 1.00 95.84  ? 40  VAL A CB  1 
ATOM   326  C  CG1 . VAL A 1 40  ? 158.708 144.809 107.874 1.00 98.80  ? 40  VAL A CG1 1 
ATOM   327  C  CG2 . VAL A 1 40  ? 159.127 143.697 110.063 1.00 92.42  ? 40  VAL A CG2 1 
ATOM   328  N  N   . VAL A 1 41  ? 162.129 144.618 106.402 1.00 102.22 ? 41  VAL A N   1 
ATOM   329  C  CA  . VAL A 1 41  ? 162.903 145.394 105.443 1.00 104.14 ? 41  VAL A CA  1 
ATOM   330  C  C   . VAL A 1 41  ? 162.089 145.576 104.173 1.00 104.65 ? 41  VAL A C   1 
ATOM   331  O  O   . VAL A 1 41  ? 161.431 144.641 103.702 1.00 108.87 ? 41  VAL A O   1 
ATOM   332  C  CB  . VAL A 1 41  ? 164.245 144.706 105.145 1.00 106.97 ? 41  VAL A CB  1 
ATOM   333  C  CG1 . VAL A 1 41  ? 165.125 145.599 104.290 1.00 107.39 ? 41  VAL A CG1 1 
ATOM   334  C  CG2 . VAL A 1 41  ? 164.949 144.349 106.439 1.00 106.30 ? 41  VAL A CG2 1 
ATOM   335  N  N   . SER A 1 42  ? 162.122 146.784 103.619 1.00 110.79 ? 42  SER A N   1 
ATOM   336  C  CA  . SER A 1 42  ? 161.490 147.033 102.336 1.00 111.89 ? 42  SER A CA  1 
ATOM   337  C  C   . SER A 1 42  ? 162.284 146.355 101.221 1.00 111.99 ? 42  SER A C   1 
ATOM   338  O  O   . SER A 1 42  ? 163.426 145.925 101.402 1.00 112.83 ? 42  SER A O   1 
ATOM   339  C  CB  . SER A 1 42  ? 161.378 148.534 102.079 1.00 116.10 ? 42  SER A CB  1 
ATOM   340  O  OG  . SER A 1 42  ? 161.231 148.803 100.697 1.00 117.72 ? 42  SER A OG  1 
ATOM   341  N  N   . ALA A 1 43  ? 161.658 146.258 100.046 1.00 110.96 ? 43  ALA A N   1 
ATOM   342  C  CA  . ALA A 1 43  ? 162.317 145.632 98.907  1.00 113.37 ? 43  ALA A CA  1 
ATOM   343  C  C   . ALA A 1 43  ? 163.539 146.414 98.441  1.00 116.92 ? 43  ALA A C   1 
ATOM   344  O  O   . ALA A 1 43  ? 164.406 145.841 97.774  1.00 115.90 ? 43  ALA A O   1 
ATOM   345  C  CB  . ALA A 1 43  ? 161.331 145.471 97.751  1.00 112.23 ? 43  ALA A CB  1 
ATOM   346  N  N   . SER A 1 44  ? 163.628 147.700 98.779  1.00 122.91 ? 44  SER A N   1 
ATOM   347  C  CA  . SER A 1 44  ? 164.779 148.515 98.421  1.00 124.97 ? 44  SER A CA  1 
ATOM   348  C  C   . SER A 1 44  ? 165.908 148.444 99.437  1.00 125.22 ? 44  SER A C   1 
ATOM   349  O  O   . SER A 1 44  ? 167.016 148.905 99.139  1.00 126.13 ? 44  SER A O   1 
ATOM   350  C  CB  . SER A 1 44  ? 164.359 149.980 98.248  1.00 123.03 ? 44  SER A CB  1 
ATOM   351  O  OG  . SER A 1 44  ? 163.164 150.081 97.495  1.00 124.28 ? 44  SER A OG  1 
ATOM   352  N  N   . GLY A 1 45  ? 165.663 147.882 100.618 1.00 120.41 ? 45  GLY A N   1 
ATOM   353  C  CA  . GLY A 1 45  ? 166.685 147.755 101.641 1.00 118.33 ? 45  GLY A CA  1 
ATOM   354  C  C   . GLY A 1 45  ? 166.467 148.604 102.876 1.00 120.17 ? 45  GLY A C   1 
ATOM   355  O  O   . GLY A 1 45  ? 167.295 148.544 103.796 1.00 121.93 ? 45  GLY A O   1 
ATOM   356  N  N   . LYS A 1 46  ? 165.402 149.395 102.950 1.00 120.85 ? 46  LYS A N   1 
ATOM   357  C  CA  . LYS A 1 46  ? 165.161 150.235 104.117 1.00 122.15 ? 46  LYS A CA  1 
ATOM   358  C  C   . LYS A 1 46  ? 164.494 149.417 105.218 1.00 120.74 ? 46  LYS A C   1 
ATOM   359  O  O   . LYS A 1 46  ? 163.492 148.739 104.974 1.00 121.38 ? 46  LYS A O   1 
ATOM   360  C  CB  . LYS A 1 46  ? 164.296 151.430 103.729 1.00 119.18 ? 46  LYS A CB  1 
ATOM   361  C  CG  . LYS A 1 46  ? 164.042 152.413 104.861 1.00 116.78 ? 46  LYS A CG  1 
ATOM   362  C  CD  . LYS A 1 46  ? 163.215 153.600 104.390 1.00 119.68 ? 46  LYS A CD  1 
ATOM   363  C  CE  . LYS A 1 46  ? 162.938 154.575 105.524 1.00 122.68 ? 46  LYS A CE  1 
ATOM   364  N  NZ  . LYS A 1 46  ? 162.129 155.739 105.071 1.00 122.52 ? 46  LYS A NZ  1 
ATOM   365  N  N   . VAL A 1 47  ? 165.038 149.437 106.429 1.00 110.96 ? 47  VAL A N   1 
ATOM   366  C  CA  . VAL A 1 47  ? 164.382 148.720 107.553 1.00 107.76 ? 47  VAL A CA  1 
ATOM   367  C  C   . VAL A 1 47  ? 163.180 149.532 108.027 1.00 105.58 ? 47  VAL A C   1 
ATOM   368  O  O   . VAL A 1 47  ? 163.355 150.689 108.389 1.00 107.24 ? 47  VAL A O   1 
ATOM   369  C  CB  . VAL A 1 47  ? 165.360 148.378 108.700 1.00 107.24 ? 47  VAL A CB  1 
ATOM   370  C  CG1 . VAL A 1 47  ? 164.684 147.584 109.805 1.00 105.46 ? 47  VAL A CG1 1 
ATOM   371  C  CG2 . VAL A 1 47  ? 166.592 147.651 108.191 1.00 104.18 ? 47  VAL A CG2 1 
ATOM   372  N  N   . LEU A 1 48  ? 162.014 148.911 108.090 1.00 96.90  ? 48  LEU A N   1 
ATOM   373  C  CA  . LEU A 1 48  ? 160.857 149.563 108.749 1.00 99.37  ? 48  LEU A CA  1 
ATOM   374  C  C   . LEU A 1 48  ? 160.929 149.465 110.272 1.00 101.66 ? 48  LEU A C   1 
ATOM   375  O  O   . LEU A 1 48  ? 160.750 150.470 110.906 1.00 105.41 ? 48  LEU A O   1 
ATOM   376  C  CB  . LEU A 1 48  ? 159.586 148.896 108.248 1.00 96.47  ? 48  LEU A CB  1 
ATOM   377  C  CG  . LEU A 1 48  ? 159.175 149.264 106.829 1.00 100.02 ? 48  LEU A CG  1 
ATOM   378  C  CD1 . LEU A 1 48  ? 159.582 148.168 105.858 1.00 102.99 ? 48  LEU A CD1 1 
ATOM   379  C  CD2 . LEU A 1 48  ? 157.676 149.533 106.773 1.00 104.39 ? 48  LEU A CD2 1 
ATOM   380  N  N   . MET A 1 49  ? 161.130 148.286 110.829 1.00 100.36 ? 49  MET A N   1 
ATOM   381  C  CA  . MET A 1 49  ? 161.093 148.109 112.277 1.00 99.98  ? 49  MET A CA  1 
ATOM   382  C  C   . MET A 1 49  ? 161.943 146.902 112.642 1.00 102.30 ? 49  MET A C   1 
ATOM   383  O  O   . MET A 1 49  ? 162.600 146.298 111.792 1.00 100.05 ? 49  MET A O   1 
ATOM   384  C  CB  . MET A 1 49  ? 159.666 147.935 112.803 1.00 96.68  ? 49  MET A CB  1 
ATOM   385  C  CG  . MET A 1 49  ? 158.841 146.907 112.058 1.00 99.58  ? 49  MET A CG  1 
ATOM   386  S  SD  . MET A 1 49  ? 157.088 147.084 112.413 1.00 112.51 ? 49  MET A SD  1 
ATOM   387  C  CE  . MET A 1 49  ? 156.529 147.910 110.932 1.00 103.97 ? 49  MET A CE  1 
ATOM   388  N  N   . ALA A 1 50  ? 161.914 146.547 113.923 1.00 100.65 ? 50  ALA A N   1 
ATOM   389  C  CA  . ALA A 1 50  ? 162.670 145.413 114.428 1.00 93.78  ? 50  ALA A CA  1 
ATOM   390  C  C   . ALA A 1 50  ? 161.916 144.782 115.591 1.00 96.43  ? 50  ALA A C   1 
ATOM   391  O  O   . ALA A 1 50  ? 160.871 145.276 116.030 1.00 101.40 ? 50  ALA A O   1 
ATOM   392  C  CB  . ALA A 1 50  ? 164.081 145.827 114.853 1.00 93.68  ? 50  ALA A CB  1 
ATOM   393  N  N   . LYS A 1 51  ? 162.469 143.673 116.086 1.00 88.76  ? 51  LYS A N   1 
ATOM   394  C  CA  . LYS A 1 51  ? 161.841 142.944 117.181 1.00 91.35  ? 51  LYS A CA  1 
ATOM   395  C  C   . LYS A 1 51  ? 161.724 143.813 118.425 1.00 97.79  ? 51  LYS A C   1 
ATOM   396  O  O   . LYS A 1 51  ? 160.704 143.774 119.126 1.00 101.31 ? 51  LYS A O   1 
ATOM   397  C  CB  . LYS A 1 51  ? 162.638 141.676 117.485 1.00 92.74  ? 51  LYS A CB  1 
ATOM   398  C  CG  . LYS A 1 51  ? 161.971 140.753 118.485 1.00 93.42  ? 51  LYS A CG  1 
ATOM   399  C  CD  . LYS A 1 51  ? 162.634 139.392 118.507 1.00 95.11  ? 51  LYS A CD  1 
ATOM   400  C  CE  . LYS A 1 51  ? 162.781 138.881 119.928 1.00 98.19  ? 51  LYS A CE  1 
ATOM   401  N  NZ  . LYS A 1 51  ? 162.362 137.459 120.048 1.00 99.71  ? 51  LYS A NZ  1 
ATOM   402  N  N   . ASP A 1 52  ? 162.760 144.601 118.715 1.00 110.92 ? 52  ASP A N   1 
ATOM   403  C  CA  . ASP A 1 52  ? 162.704 145.502 119.860 1.00 111.86 ? 52  ASP A CA  1 
ATOM   404  C  C   . ASP A 1 52  ? 161.609 146.545 119.689 1.00 110.86 ? 52  ASP A C   1 
ATOM   405  O  O   . ASP A 1 52  ? 160.919 146.893 120.651 1.00 113.04 ? 52  ASP A O   1 
ATOM   406  C  CB  . ASP A 1 52  ? 164.061 146.173 120.067 1.00 111.03 ? 52  ASP A CB  1 
ATOM   407  C  CG  . ASP A 1 52  ? 164.997 145.334 120.911 1.00 116.53 ? 52  ASP A CG  1 
ATOM   408  O  OD1 . ASP A 1 52  ? 164.676 144.154 121.162 1.00 116.49 ? 52  ASP A OD1 1 
ATOM   409  O  OD2 . ASP A 1 52  ? 166.053 145.855 121.325 1.00 116.28 ? 52  ASP A OD2 1 
ATOM   410  N  N   . ASP A 1 53  ? 161.437 147.058 118.468 1.00 94.95  ? 53  ASP A N   1 
ATOM   411  C  CA  . ASP A 1 53  ? 160.368 148.019 118.220 1.00 90.76  ? 53  ASP A CA  1 
ATOM   412  C  C   . ASP A 1 53  ? 158.997 147.389 118.434 1.00 93.57  ? 53  ASP A C   1 
ATOM   413  O  O   . ASP A 1 53  ? 158.102 148.013 119.019 1.00 99.28  ? 53  ASP A O   1 
ATOM   414  C  CB  . ASP A 1 53  ? 160.484 148.580 116.804 1.00 94.60  ? 53  ASP A CB  1 
ATOM   415  C  CG  . ASP A 1 53  ? 161.793 149.301 116.571 1.00 104.52 ? 53  ASP A CG  1 
ATOM   416  O  OD1 . ASP A 1 53  ? 162.166 150.141 117.414 1.00 105.97 ? 53  ASP A OD1 1 
ATOM   417  O  OD2 . ASP A 1 53  ? 162.448 149.032 115.542 1.00 108.12 ? 53  ASP A OD2 1 
ATOM   418  N  N   . ILE A 1 54  ? 158.813 146.151 117.972 1.00 79.76  ? 54  ILE A N   1 
ATOM   419  C  CA  . ILE A 1 54  ? 157.528 145.483 118.165 1.00 77.63  ? 54  ILE A CA  1 
ATOM   420  C  C   . ILE A 1 54  ? 157.260 145.241 119.648 1.00 81.57  ? 54  ILE A C   1 
ATOM   421  O  O   . ILE A 1 54  ? 156.133 145.412 120.127 1.00 87.55  ? 54  ILE A O   1 
ATOM   422  C  CB  . ILE A 1 54  ? 157.478 144.177 117.353 1.00 71.84  ? 54  ILE A CB  1 
ATOM   423  C  CG1 . ILE A 1 54  ? 157.792 144.458 115.884 1.00 73.43  ? 54  ILE A CG1 1 
ATOM   424  C  CG2 . ILE A 1 54  ? 156.116 143.525 117.481 1.00 74.31  ? 54  ILE A CG2 1 
ATOM   425  C  CD1 . ILE A 1 54  ? 157.745 143.235 115.004 1.00 73.83  ? 54  ILE A CD1 1 
ATOM   426  N  N   . LEU A 1 55  ? 158.287 144.836 120.399 1.00 82.37  ? 55  LEU A N   1 
ATOM   427  C  CA  . LEU A 1 55  ? 158.107 144.614 121.831 1.00 83.40  ? 55  LEU A CA  1 
ATOM   428  C  C   . LEU A 1 55  ? 157.815 145.917 122.567 1.00 90.68  ? 55  LEU A C   1 
ATOM   429  O  O   . LEU A 1 55  ? 156.992 145.946 123.492 1.00 96.37  ? 55  LEU A O   1 
ATOM   430  C  CB  . LEU A 1 55  ? 159.340 143.923 122.410 1.00 84.92  ? 55  LEU A CB  1 
ATOM   431  C  CG  . LEU A 1 55  ? 159.510 142.470 121.967 1.00 86.25  ? 55  LEU A CG  1 
ATOM   432  C  CD1 . LEU A 1 55  ? 160.851 141.917 122.410 1.00 91.26  ? 55  LEU A CD1 1 
ATOM   433  C  CD2 . LEU A 1 55  ? 158.371 141.614 122.494 1.00 81.10  ? 55  LEU A CD2 1 
ATOM   434  N  N   . ALA A 1 56  ? 158.473 147.008 122.169 1.00 78.41  ? 56  ALA A N   1 
ATOM   435  C  CA  . ALA A 1 56  ? 158.170 148.311 122.748 1.00 79.52  ? 56  ALA A CA  1 
ATOM   436  C  C   . ALA A 1 56  ? 156.739 148.727 122.444 1.00 80.78  ? 56  ALA A C   1 
ATOM   437  O  O   . ALA A 1 56  ? 156.066 149.326 123.290 1.00 86.82  ? 56  ALA A O   1 
ATOM   438  C  CB  . ALA A 1 56  ? 159.157 149.355 122.233 1.00 84.70  ? 56  ALA A CB  1 
ATOM   439  N  N   . GLY A 1 57  ? 156.256 148.421 121.239 1.00 77.08  ? 57  GLY A N   1 
ATOM   440  C  CA  . GLY A 1 57  ? 154.867 148.701 120.922 1.00 81.41  ? 57  GLY A CA  1 
ATOM   441  C  C   . GLY A 1 57  ? 153.897 147.881 121.748 1.00 80.44  ? 57  GLY A C   1 
ATOM   442  O  O   . GLY A 1 57  ? 152.837 148.370 122.143 1.00 84.72  ? 57  GLY A O   1 
ATOM   443  N  N   . GLN A 1 58  ? 154.241 146.622 122.012 1.00 71.98  ? 58  GLN A N   1 
ATOM   444  C  CA  . GLN A 1 58  ? 153.424 145.801 122.901 1.00 68.46  ? 58  GLN A CA  1 
ATOM   445  C  C   . GLN A 1 58  ? 153.371 146.400 124.304 1.00 75.01  ? 58  GLN A C   1 
ATOM   446  O  O   . GLN A 1 58  ? 152.303 146.451 124.933 1.00 80.83  ? 58  GLN A O   1 
ATOM   447  C  CB  . GLN A 1 58  ? 153.976 144.376 122.927 1.00 64.70  ? 58  GLN A CB  1 
ATOM   448  C  CG  . GLN A 1 58  ? 153.317 143.445 123.922 1.00 74.86  ? 58  GLN A CG  1 
ATOM   449  C  CD  . GLN A 1 58  ? 153.768 142.009 123.742 1.00 79.18  ? 58  GLN A CD  1 
ATOM   450  O  OE1 . GLN A 1 58  ? 154.016 141.562 122.625 1.00 73.26  ? 58  GLN A OE1 1 
ATOM   451  N  NE2 . GLN A 1 58  ? 153.882 141.282 124.845 1.00 80.71  ? 58  GLN A NE2 1 
ATOM   452  N  N   . SER A 1 59  ? 154.490 146.857 124.857 1.00 76.87  ? 59  SER A N   1 
ATOM   453  C  CA  . SER A 1 59  ? 154.539 147.552 126.174 1.00 77.21  ? 59  SER A CA  1 
ATOM   454  C  C   . SER A 1 59  ? 153.722 148.854 126.135 1.00 85.87  ? 59  SER A C   1 
ATOM   455  O  O   . SER A 1 59  ? 152.961 149.057 127.071 1.00 89.98  ? 59  SER A O   1 
ATOM   456  C  CB  . SER A 1 59  ? 155.950 147.712 126.711 1.00 77.75  ? 59  SER A CB  1 
ATOM   457  O  OG  . SER A 1 59  ? 156.498 146.464 127.031 1.00 88.03  ? 59  SER A OG  1 
ATOM   458  N  N   . ALA A 1 60  ? 153.754 149.595 125.021 1.00 76.53  ? 60  ALA A N   1 
ATOM   459  C  CA  . ALA A 1 60  ? 152.939 150.803 124.922 1.00 69.73  ? 60  ALA A CA  1 
ATOM   460  C  C   . ALA A 1 60  ? 151.452 150.470 124.888 1.00 70.89  ? 60  ALA A C   1 
ATOM   461  O  O   . ALA A 1 60  ? 150.630 151.198 125.454 1.00 81.60  ? 60  ALA A O   1 
ATOM   462  C  CB  . ALA A 1 60  ? 153.339 151.604 123.684 1.00 62.49  ? 60  ALA A CB  1 
ATOM   463  N  N   . TRP A 1 61  ? 151.092 149.381 124.209 1.00 67.02  ? 61  TRP A N   1 
ATOM   464  C  CA  . TRP A 1 61  ? 149.708 148.918 124.207 1.00 68.28  ? 61  TRP A CA  1 
ATOM   465  C  C   . TRP A 1 61  ? 149.255 148.565 125.619 1.00 72.58  ? 61  TRP A C   1 
ATOM   466  O  O   . TRP A 1 61  ? 148.139 148.913 126.035 1.00 81.06  ? 61  TRP A O   1 
ATOM   467  C  CB  . TRP A 1 61  ? 149.590 147.716 123.267 1.00 67.27  ? 61  TRP A CB  1 
ATOM   468  C  CG  . TRP A 1 61  ? 148.246 147.080 123.184 1.00 66.16  ? 61  TRP A CG  1 
ATOM   469  C  CD1 . TRP A 1 61  ? 147.077 147.675 122.820 1.00 68.51  ? 61  TRP A CD1 1 
ATOM   470  C  CD2 . TRP A 1 61  ? 147.936 145.705 123.431 1.00 75.42  ? 61  TRP A CD2 1 
ATOM   471  N  NE1 . TRP A 1 61  ? 146.055 146.762 122.840 1.00 77.57  ? 61  TRP A NE1 1 
ATOM   472  C  CE2 . TRP A 1 61  ? 146.558 145.542 123.209 1.00 81.48  ? 61  TRP A CE2 1 
ATOM   473  C  CE3 . TRP A 1 61  ? 148.691 144.597 123.823 1.00 73.41  ? 61  TRP A CE3 1 
ATOM   474  C  CZ2 . TRP A 1 61  ? 145.915 144.318 123.375 1.00 77.72  ? 61  TRP A CZ2 1 
ATOM   475  C  CZ3 . TRP A 1 61  ? 148.054 143.384 123.982 1.00 71.51  ? 61  TRP A CZ3 1 
ATOM   476  C  CH2 . TRP A 1 61  ? 146.681 143.253 123.758 1.00 72.59  ? 61  TRP A CH2 1 
ATOM   477  N  N   . GLN A 1 62  ? 150.121 147.889 126.378 1.00 68.15  ? 62  GLN A N   1 
ATOM   478  C  CA  . GLN A 1 62  ? 149.809 147.613 127.778 1.00 66.19  ? 62  GLN A CA  1 
ATOM   479  C  C   . GLN A 1 62  ? 149.588 148.903 128.561 1.00 70.93  ? 62  GLN A C   1 
ATOM   480  O  O   . GLN A 1 62  ? 148.664 148.992 129.375 1.00 74.54  ? 62  GLN A O   1 
ATOM   481  C  CB  . GLN A 1 62  ? 150.923 146.787 128.413 1.00 68.64  ? 62  GLN A CB  1 
ATOM   482  C  CG  . GLN A 1 62  ? 151.108 145.411 127.804 1.00 70.83  ? 62  GLN A CG  1 
ATOM   483  C  CD  . GLN A 1 62  ? 152.370 144.733 128.287 1.00 79.41  ? 62  GLN A CD  1 
ATOM   484  O  OE1 . GLN A 1 62  ? 153.128 145.295 129.072 1.00 90.23  ? 62  GLN A OE1 1 
ATOM   485  N  NE2 . GLN A 1 62  ? 152.608 143.518 127.813 1.00 76.84  ? 62  GLN A NE2 1 
ATOM   486  N  N   . THR A 1 63  ? 150.277 150.045 128.421 1.00 77.08  ? 63  THR A N   1 
ATOM   487  C  CA  . THR A 1 63  ? 149.999 151.312 129.174 1.00 72.70  ? 63  THR A CA  1 
ATOM   488  C  C   . THR A 1 63  ? 148.690 152.071 128.793 1.00 71.32  ? 63  THR A C   1 
ATOM   489  O  O   . THR A 1 63  ? 148.316 152.974 129.531 1.00 80.93  ? 63  THR A O   1 
ATOM   490  C  CB  . THR A 1 63  ? 151.263 152.203 129.235 1.00 72.94  ? 63  THR A CB  1 
ATOM   491  O  OG1 . THR A 1 63  ? 151.249 153.006 128.057 1.00 82.82  ? 63  THR A OG1 1 
ATOM   492  C  CG2 . THR A 1 63  ? 152.567 151.450 129.331 1.00 79.84  ? 63  THR A CG2 1 
ATOM   493  N  N   . THR A 1 64  ? 147.970 151.716 127.760 1.00 75.77  ? 64  THR A N   1 
ATOM   494  C  CA  . THR A 1 64  ? 146.690 152.284 127.319 1.00 73.57  ? 64  THR A CA  1 
ATOM   495  C  C   . THR A 1 64  ? 145.503 151.478 127.858 1.00 76.86  ? 64  THR A C   1 
ATOM   496  O  O   . THR A 1 64  ? 144.422 151.986 127.828 1.00 82.89  ? 64  THR A O   1 
ATOM   497  C  CB  . THR A 1 64  ? 146.686 152.274 125.771 1.00 69.52  ? 64  THR A CB  1 
ATOM   498  O  OG1 . THR A 1 64  ? 146.502 150.947 125.285 1.00 68.69  ? 64  THR A OG1 1 
ATOM   499  C  CG2 . THR A 1 64  ? 147.894 152.944 125.151 1.00 80.19  ? 64  THR A CG2 1 
ATOM   500  N  N   . GLY A 1 65  ? 145.743 150.322 128.446 1.00 75.23  ? 65  GLY A N   1 
ATOM   501  C  CA  . GLY A 1 65  ? 144.721 149.358 128.779 1.00 66.82  ? 65  GLY A CA  1 
ATOM   502  C  C   . GLY A 1 65  ? 144.780 148.110 127.936 1.00 72.58  ? 65  GLY A C   1 
ATOM   503  O  O   . GLY A 1 65  ? 144.054 147.239 128.405 1.00 73.49  ? 65  GLY A O   1 
ATOM   504  N  N   . GLY A 1 66  ? 145.624 147.985 126.819 1.00 80.69  ? 66  GLY A N   1 
ATOM   505  C  CA  . GLY A 1 66  ? 145.546 146.697 126.168 1.00 81.74  ? 66  GLY A CA  1 
ATOM   506  C  C   . GLY A 1 66  ? 144.156 146.317 125.712 1.00 74.34  ? 66  GLY A C   1 
ATOM   507  O  O   . GLY A 1 66  ? 143.511 147.055 124.962 1.00 78.02  ? 66  GLY A O   1 
ATOM   508  N  N   . MET A 1 67  ? 143.684 145.163 126.173 1.00 67.05  ? 67  MET A N   1 
ATOM   509  C  CA  . MET A 1 67  ? 142.408 144.616 125.737 1.00 64.28  ? 67  MET A CA  1 
ATOM   510  C  C   . MET A 1 67  ? 141.203 145.393 126.249 1.00 72.85  ? 67  MET A C   1 
ATOM   511  O  O   . MET A 1 67  ? 140.089 145.150 125.779 1.00 80.28  ? 67  MET A O   1 
ATOM   512  C  CB  . MET A 1 67  ? 142.298 143.154 126.174 1.00 64.43  ? 67  MET A CB  1 
ATOM   513  C  CG  . MET A 1 67  ? 143.264 142.225 125.468 1.00 76.30  ? 67  MET A CG  1 
ATOM   514  S  SD  . MET A 1 67  ? 143.281 140.571 126.178 1.00 83.61  ? 67  MET A SD  1 
ATOM   515  C  CE  . MET A 1 67  ? 144.690 139.861 125.338 1.00 73.48  ? 67  MET A CE  1 
ATOM   516  N  N   . GLU A 1 68  ? 141.386 146.316 127.187 1.00 79.66  ? 68  GLU A N   1 
ATOM   517  C  CA  . GLU A 1 68  ? 140.260 147.036 127.762 1.00 76.77  ? 68  GLU A CA  1 
ATOM   518  C  C   . GLU A 1 68  ? 139.860 148.268 126.964 1.00 76.53  ? 68  GLU A C   1 
ATOM   519  O  O   . GLU A 1 68  ? 138.868 148.916 127.311 1.00 80.70  ? 68  GLU A O   1 
ATOM   520  C  CB  . GLU A 1 68  ? 140.568 147.434 129.206 1.00 74.49  ? 68  GLU A CB  1 
ATOM   521  C  CG  . GLU A 1 68  ? 140.919 146.256 130.097 1.00 81.02  ? 68  GLU A CG  1 
ATOM   522  C  CD  . GLU A 1 68  ? 139.700 145.453 130.511 1.00 87.52  ? 68  GLU A CD  1 
ATOM   523  O  OE1 . GLU A 1 68  ? 138.569 145.905 130.252 1.00 88.31  ? 68  GLU A OE1 1 
ATOM   524  O  OE2 . GLU A 1 68  ? 139.876 144.367 131.098 1.00 85.38  ? 68  GLU A OE2 1 
ATOM   525  N  N   . VAL A 1 69  ? 140.525 148.515 125.820 1.00 81.32  ? 69  VAL A N   1 
ATOM   526  C  CA  . VAL A 1 69  ? 140.251 149.599 124.831 1.00 85.65  ? 69  VAL A CA  1 
ATOM   527  C  C   . VAL A 1 69  ? 140.336 148.886 123.477 1.00 89.02  ? 69  VAL A C   1 
ATOM   528  O  O   . VAL A 1 69  ? 141.413 148.752 122.938 1.00 96.86  ? 69  VAL A O   1 
ATOM   529  C  CB  . VAL A 1 69  ? 141.160 150.866 124.908 1.00 78.82  ? 69  VAL A CB  1 
ATOM   530  C  CG1 . VAL A 1 69  ? 141.133 151.691 123.630 1.00 76.21  ? 69  VAL A CG1 1 
ATOM   531  C  CG2 . VAL A 1 69  ? 140.880 151.725 126.125 1.00 84.35  ? 69  VAL A CG2 1 
ATOM   532  N  N   . GLY A 1 70  ? 139.217 148.477 122.919 1.00 70.90  ? 70  GLY A N   1 
ATOM   533  C  CA  . GLY A 1 70  ? 139.222 147.669 121.691 1.00 68.29  ? 70  GLY A CA  1 
ATOM   534  C  C   . GLY A 1 70  ? 139.634 146.220 121.846 1.00 79.96  ? 70  GLY A C   1 
ATOM   535  O  O   . GLY A 1 70  ? 139.572 145.701 122.946 1.00 92.18  ? 70  GLY A O   1 
ATOM   536  N  N   . SER A 1 71  ? 140.261 145.641 120.830 1.00 78.70  ? 71  SER A N   1 
ATOM   537  C  CA  . SER A 1 71  ? 140.460 144.204 120.757 1.00 77.22  ? 71  SER A CA  1 
ATOM   538  C  C   . SER A 1 71  ? 141.654 143.917 119.862 1.00 83.17  ? 71  SER A C   1 
ATOM   539  O  O   . SER A 1 71  ? 141.828 144.558 118.825 1.00 83.38  ? 71  SER A O   1 
ATOM   540  C  CB  . SER A 1 71  ? 139.209 143.497 120.227 1.00 79.64  ? 71  SER A CB  1 
ATOM   541  O  OG  . SER A 1 71  ? 139.288 142.100 120.424 1.00 76.27  ? 71  SER A OG  1 
ATOM   542  N  N   . VAL A 1 72  ? 142.479 142.959 120.276 1.00 74.66  ? 72  VAL A N   1 
ATOM   543  C  CA  . VAL A 1 72  ? 143.619 142.507 119.488 1.00 61.21  ? 72  VAL A CA  1 
ATOM   544  C  C   . VAL A 1 72  ? 143.514 140.997 119.340 1.00 70.54  ? 72  VAL A C   1 
ATOM   545  O  O   . VAL A 1 72  ? 143.420 140.279 120.342 1.00 80.54  ? 72  VAL A O   1 
ATOM   546  C  CB  . VAL A 1 72  ? 144.963 142.902 120.127 1.00 53.50  ? 72  VAL A CB  1 
ATOM   547  C  CG1 . VAL A 1 72  ? 146.094 142.080 119.535 1.00 61.37  ? 72  VAL A CG1 1 
ATOM   548  C  CG2 . VAL A 1 72  ? 145.223 144.384 119.923 1.00 60.73  ? 72  VAL A CG2 1 
ATOM   549  N  N   . LEU A 1 73  ? 143.524 140.523 118.095 1.00 65.37  ? 73  LEU A N   1 
ATOM   550  C  CA  . LEU A 1 73  ? 143.418 139.103 117.768 1.00 66.06  ? 73  LEU A CA  1 
ATOM   551  C  C   . LEU A 1 73  ? 142.146 138.480 118.337 1.00 73.76  ? 73  LEU A C   1 
ATOM   552  O  O   . LEU A 1 73  ? 142.132 137.305 118.708 1.00 80.07  ? 73  LEU A O   1 
ATOM   553  C  CB  . LEU A 1 73  ? 144.655 138.332 118.238 1.00 68.49  ? 73  LEU A CB  1 
ATOM   554  C  CG  . LEU A 1 73  ? 145.920 138.562 117.409 1.00 64.43  ? 73  LEU A CG  1 
ATOM   555  C  CD1 . LEU A 1 73  ? 147.125 137.940 118.088 1.00 64.85  ? 73  LEU A CD1 1 
ATOM   556  C  CD2 . LEU A 1 73  ? 145.753 138.015 116.002 1.00 63.64  ? 73  LEU A CD2 1 
ATOM   557  N  N   . GLY A 1 74  ? 141.070 139.262 118.405 1.00 71.28  ? 74  GLY A N   1 
ATOM   558  C  CA  . GLY A 1 74  ? 139.777 138.762 118.811 1.00 71.82  ? 74  GLY A CA  1 
ATOM   559  C  C   . GLY A 1 74  ? 139.480 138.818 120.294 1.00 75.27  ? 74  GLY A C   1 
ATOM   560  O  O   . GLY A 1 74  ? 138.361 138.473 120.695 1.00 83.15  ? 74  GLY A O   1 
ATOM   561  N  N   . HIS A 1 75  ? 140.431 139.240 121.121 1.00 72.27  ? 75  HIS A N   1 
ATOM   562  C  CA  . HIS A 1 75  ? 140.246 139.300 122.564 1.00 70.75  ? 75  HIS A CA  1 
ATOM   563  C  C   . HIS A 1 75  ? 140.309 140.745 123.036 1.00 75.60  ? 75  HIS A C   1 
ATOM   564  O  O   . HIS A 1 75  ? 141.238 141.478 122.682 1.00 79.66  ? 75  HIS A O   1 
ATOM   565  C  CB  . HIS A 1 75  ? 141.304 138.466 123.288 1.00 74.32  ? 75  HIS A CB  1 
ATOM   566  C  CG  . HIS A 1 75  ? 141.158 136.991 123.076 1.00 79.05  ? 75  HIS A CG  1 
ATOM   567  N  ND1 . HIS A 1 75  ? 142.238 136.157 122.887 1.00 81.64  ? 75  HIS A ND1 1 
ATOM   568  C  CD2 . HIS A 1 75  ? 140.060 136.202 123.028 1.00 74.85  ? 75  HIS A CD2 1 
ATOM   569  C  CE1 . HIS A 1 75  ? 141.811 134.917 122.733 1.00 75.24  ? 75  HIS A CE1 1 
ATOM   570  N  NE2 . HIS A 1 75  ? 140.493 134.917 122.813 1.00 73.49  ? 75  HIS A NE2 1 
ATOM   571  N  N   . GLY A 1 76  ? 139.329 141.149 123.826 1.00 83.13  ? 76  GLY A N   1 
ATOM   572  C  CA  . GLY A 1 76  ? 139.329 142.471 124.415 1.00 81.70  ? 76  GLY A CA  1 
ATOM   573  C  C   . GLY A 1 76  ? 137.925 143.030 124.511 1.00 83.05  ? 76  GLY A C   1 
ATOM   574  O  O   . GLY A 1 76  ? 136.953 142.288 124.600 1.00 88.63  ? 76  GLY A O   1 
ATOM   575  N  N   . ALA A 1 77  ? 137.853 144.358 124.501 1.00 61.70  ? 77  ALA A N   1 
ATOM   576  C  CA  . ALA A 1 77  ? 136.594 145.081 124.580 1.00 60.65  ? 77  ALA A CA  1 
ATOM   577  C  C   . ALA A 1 77  ? 135.934 145.143 123.204 1.00 67.86  ? 77  ALA A C   1 
ATOM   578  O  O   . ALA A 1 77  ? 136.544 144.841 122.176 1.00 74.27  ? 77  ALA A O   1 
ATOM   579  C  CB  . ALA A 1 77  ? 136.823 146.478 125.151 1.00 66.45  ? 77  ALA A CB  1 
ATOM   580  N  N   . TYR A 1 78  ? 134.661 145.542 123.181 1.00 69.18  ? 78  TYR A N   1 
ATOM   581  C  CA  . TYR A 1 78  ? 133.860 145.463 121.969 1.00 74.87  ? 78  TYR A CA  1 
ATOM   582  C  C   . TYR A 1 78  ? 133.323 146.798 121.471 1.00 81.00  ? 78  TYR A C   1 
ATOM   583  O  O   . TYR A 1 78  ? 132.607 146.812 120.465 1.00 86.89  ? 78  TYR A O   1 
ATOM   584  C  CB  . TYR A 1 78  ? 132.676 144.508 122.178 1.00 70.03  ? 78  TYR A CB  1 
ATOM   585  C  CG  . TYR A 1 78  ? 133.075 143.149 122.696 1.00 71.55  ? 78  TYR A CG  1 
ATOM   586  C  CD1 . TYR A 1 78  ? 134.222 142.517 122.238 1.00 77.17  ? 78  TYR A CD1 1 
ATOM   587  C  CD2 . TYR A 1 78  ? 132.313 142.505 123.658 1.00 69.20  ? 78  TYR A CD2 1 
ATOM   588  C  CE1 . TYR A 1 78  ? 134.591 141.279 122.716 1.00 82.18  ? 78  TYR A CE1 1 
ATOM   589  C  CE2 . TYR A 1 78  ? 132.673 141.269 124.138 1.00 73.08  ? 78  TYR A CE2 1 
ATOM   590  C  CZ  . TYR A 1 78  ? 133.813 140.659 123.667 1.00 77.23  ? 78  TYR A CZ  1 
ATOM   591  O  OH  . TYR A 1 78  ? 134.172 139.424 124.148 1.00 80.18  ? 78  TYR A OH  1 
ATOM   592  N  N   . GLN A 1 79  ? 133.589 147.931 122.098 1.00 81.02  ? 79  GLN A N   1 
ATOM   593  C  CA  . GLN A 1 79  ? 133.097 149.280 121.664 1.00 76.84  ? 79  GLN A CA  1 
ATOM   594  C  C   . GLN A 1 79  ? 134.075 149.880 120.639 1.00 78.65  ? 79  GLN A C   1 
ATOM   595  O  O   . GLN A 1 79  ? 133.611 150.425 119.648 1.00 81.26  ? 79  GLN A O   1 
ATOM   596  C  CB  . GLN A 1 79  ? 132.830 150.278 122.812 1.00 80.29  ? 79  GLN A CB  1 
ATOM   597  C  CG  . GLN A 1 79  ? 132.109 151.552 122.398 1.00 78.76  ? 79  GLN A CG  1 
ATOM   598  C  CD  . GLN A 1 79  ? 130.667 151.369 121.990 1.00 80.67  ? 79  GLN A CD  1 
ATOM   599  O  OE1 . GLN A 1 79  ? 130.017 150.384 122.310 1.00 89.91  ? 79  GLN A OE1 1 
ATOM   600  N  NE2 . GLN A 1 79  ? 130.150 152.328 121.252 1.00 77.41  ? 79  GLN A NE2 1 
ATOM   601  N  N   . ALA A 1 80  ? 135.373 149.866 120.932 1.00 80.62  ? 80  ALA A N   1 
ATOM   602  C  CA  . ALA A 1 80  ? 136.363 150.234 119.937 1.00 77.81  ? 80  ALA A CA  1 
ATOM   603  C  C   . ALA A 1 80  ? 136.559 149.080 118.954 1.00 82.63  ? 80  ALA A C   1 
ATOM   604  O  O   . ALA A 1 80  ? 136.301 147.922 119.290 1.00 86.05  ? 80  ALA A O   1 
ATOM   605  C  CB  . ALA A 1 80  ? 137.687 150.586 120.606 1.00 80.17  ? 80  ALA A CB  1 
ATOM   606  N  N   . PRO A 1 81  ? 137.001 149.367 117.731 1.00 74.21  ? 81  PRO A N   1 
ATOM   607  C  CA  . PRO A 1 81  ? 137.141 148.299 116.738 1.00 77.25  ? 81  PRO A CA  1 
ATOM   608  C  C   . PRO A 1 81  ? 138.274 147.347 117.081 1.00 74.23  ? 81  PRO A C   1 
ATOM   609  O  O   . PRO A 1 81  ? 139.197 147.681 117.828 1.00 84.97  ? 81  PRO A O   1 
ATOM   610  C  CB  . PRO A 1 81  ? 137.437 149.060 115.439 1.00 71.04  ? 81  PRO A CB  1 
ATOM   611  C  CG  . PRO A 1 81  ? 138.061 150.323 115.893 1.00 67.01  ? 81  PRO A CG  1 
ATOM   612  C  CD  . PRO A 1 81  ? 137.376 150.678 117.177 1.00 68.93  ? 81  PRO A CD  1 
ATOM   613  N  N   . ASP A 1 82  ? 138.184 146.140 116.530 1.00 77.26  ? 82  ASP A N   1 
ATOM   614  C  CA  . ASP A 1 82  ? 139.287 145.194 116.627 1.00 72.96  ? 82  ASP A CA  1 
ATOM   615  C  C   . ASP A 1 82  ? 140.474 145.712 115.826 1.00 83.09  ? 82  ASP A C   1 
ATOM   616  O  O   . ASP A 1 82  ? 140.382 145.893 114.607 1.00 91.88  ? 82  ASP A O   1 
ATOM   617  C  CB  . ASP A 1 82  ? 138.844 143.823 116.127 1.00 82.56  ? 82  ASP A CB  1 
ATOM   618  C  CG  . ASP A 1 82  ? 139.883 142.756 116.364 1.00 89.44  ? 82  ASP A CG  1 
ATOM   619  O  OD1 . ASP A 1 82  ? 140.822 142.660 115.553 1.00 93.89  ? 82  ASP A OD1 1 
ATOM   620  O  OD2 . ASP A 1 82  ? 139.771 142.019 117.364 1.00 91.63  ? 82  ASP A OD2 1 
ATOM   621  N  N   . TRP A 1 83  ? 141.588 145.949 116.518 1.00 65.03  ? 83  TRP A N   1 
ATOM   622  C  CA  . TRP A 1 83  ? 142.663 146.751 115.941 1.00 60.69  ? 83  TRP A CA  1 
ATOM   623  C  C   . TRP A 1 83  ? 143.388 146.016 114.822 1.00 66.77  ? 83  TRP A C   1 
ATOM   624  O  O   . TRP A 1 83  ? 143.697 146.618 113.789 1.00 72.52  ? 83  TRP A O   1 
ATOM   625  C  CB  . TRP A 1 83  ? 143.641 147.177 117.035 1.00 60.63  ? 83  TRP A CB  1 
ATOM   626  C  CG  . TRP A 1 83  ? 143.020 148.088 118.045 1.00 68.12  ? 83  TRP A CG  1 
ATOM   627  C  CD1 . TRP A 1 83  ? 142.869 147.852 119.377 1.00 71.21  ? 83  TRP A CD1 1 
ATOM   628  C  CD2 . TRP A 1 83  ? 142.449 149.380 117.801 1.00 64.91  ? 83  TRP A CD2 1 
ATOM   629  N  NE1 . TRP A 1 83  ? 142.247 148.914 119.981 1.00 73.20  ? 83  TRP A NE1 1 
ATOM   630  C  CE2 . TRP A 1 83  ? 141.979 149.868 119.036 1.00 66.86  ? 83  TRP A CE2 1 
ATOM   631  C  CE3 . TRP A 1 83  ? 142.295 150.175 116.661 1.00 61.97  ? 83  TRP A CE3 1 
ATOM   632  C  CZ2 . TRP A 1 83  ? 141.365 151.110 119.161 1.00 69.40  ? 83  TRP A CZ2 1 
ATOM   633  C  CZ3 . TRP A 1 83  ? 141.685 151.406 116.790 1.00 65.41  ? 83  TRP A CZ3 1 
ATOM   634  C  CH2 . TRP A 1 83  ? 141.229 151.862 118.030 1.00 68.73  ? 83  TRP A CH2 1 
ATOM   635  N  N   . THR A 1 84  ? 143.617 144.713 115.005 1.00 60.87  ? 84  THR A N   1 
ATOM   636  C  CA  . THR A 1 84  ? 144.328 143.839 114.035 1.00 59.36  ? 84  THR A CA  1 
ATOM   637  C  C   . THR A 1 84  ? 143.545 143.742 112.744 1.00 70.09  ? 84  THR A C   1 
ATOM   638  O  O   . THR A 1 84  ? 144.130 143.801 111.699 1.00 88.16  ? 84  THR A O   1 
ATOM   639  C  CB  . THR A 1 84  ? 144.508 142.410 114.573 1.00 68.57  ? 84  THR A CB  1 
ATOM   640  O  OG1 . THR A 1 84  ? 145.239 142.451 115.794 1.00 76.42  ? 84  THR A OG1 1 
ATOM   641  C  CG2 . THR A 1 84  ? 145.213 141.484 113.608 1.00 71.44  ? 84  THR A CG2 1 
ATOM   642  N  N   . ALA A 1 85  ? 142.265 143.554 112.853 1.00 54.81  ? 85  ALA A N   1 
ATOM   643  C  CA  . ALA A 1 85  ? 141.387 143.453 111.689 1.00 60.84  ? 85  ALA A CA  1 
ATOM   644  C  C   . ALA A 1 85  ? 141.231 144.798 110.992 1.00 66.60  ? 85  ALA A C   1 
ATOM   645  O  O   . ALA A 1 85  ? 141.259 144.872 109.756 1.00 76.87  ? 85  ALA A O   1 
ATOM   646  C  CB  . ALA A 1 85  ? 140.025 142.901 112.105 1.00 57.65  ? 85  ALA A CB  1 
ATOM   647  N  N   . ASP A 1 86  ? 141.066 145.874 111.766 1.00 69.03  ? 86  ASP A N   1 
ATOM   648  C  CA  . ASP A 1 86  ? 140.930 147.200 111.174 1.00 71.68  ? 86  ASP A CA  1 
ATOM   649  C  C   . ASP A 1 86  ? 142.197 147.607 110.432 1.00 75.81  ? 86  ASP A C   1 
ATOM   650  O  O   . ASP A 1 86  ? 142.129 148.129 109.311 1.00 84.66  ? 86  ASP A O   1 
ATOM   651  C  CB  . ASP A 1 86  ? 140.589 148.220 112.262 1.00 74.31  ? 86  ASP A CB  1 
ATOM   652  C  CG  . ASP A 1 86  ? 140.028 149.506 111.699 1.00 86.32  ? 86  ASP A CG  1 
ATOM   653  O  OD1 . ASP A 1 86  ? 138.866 149.499 111.246 1.00 91.68  ? 86  ASP A OD1 1 
ATOM   654  O  OD2 . ASP A 1 86  ? 140.746 150.525 111.714 1.00 88.87  ? 86  ASP A OD2 1 
ATOM   655  N  N   . TRP A 1 87  ? 143.363 147.372 111.042 1.00 66.95  ? 87  TRP A N   1 
ATOM   656  C  CA  . TRP A 1 87  ? 144.627 147.688 110.388 1.00 63.34  ? 87  TRP A CA  1 
ATOM   657  C  C   . TRP A 1 87  ? 144.800 146.874 109.116 1.00 67.54  ? 87  TRP A C   1 
ATOM   658  O  O   . TRP A 1 87  ? 145.235 147.404 108.088 1.00 70.88  ? 87  TRP A O   1 
ATOM   659  C  CB  . TRP A 1 87  ? 145.791 147.441 111.347 1.00 60.41  ? 87  TRP A CB  1 
ATOM   660  C  CG  . TRP A 1 87  ? 147.141 147.763 110.773 1.00 70.07  ? 87  TRP A CG  1 
ATOM   661  C  CD1 . TRP A 1 87  ? 147.844 147.028 109.863 1.00 71.45  ? 87  TRP A CD1 1 
ATOM   662  C  CD2 . TRP A 1 87  ? 147.952 148.902 111.077 1.00 73.36  ? 87  TRP A CD2 1 
ATOM   663  N  NE1 . TRP A 1 87  ? 149.037 147.641 109.578 1.00 68.93  ? 87  TRP A NE1 1 
ATOM   664  C  CE2 . TRP A 1 87  ? 149.128 148.794 110.309 1.00 69.70  ? 87  TRP A CE2 1 
ATOM   665  C  CE3 . TRP A 1 87  ? 147.797 150.007 111.920 1.00 71.16  ? 87  TRP A CE3 1 
ATOM   666  C  CZ2 . TRP A 1 87  ? 150.141 149.743 110.362 1.00 68.88  ? 87  TRP A CZ2 1 
ATOM   667  C  CZ3 . TRP A 1 87  ? 148.803 150.947 111.968 1.00 75.60  ? 87  TRP A CZ3 1 
ATOM   668  C  CH2 . TRP A 1 87  ? 149.961 150.813 111.195 1.00 75.25  ? 87  TRP A CH2 1 
ATOM   669  N  N   . LEU A 1 88  ? 144.467 145.582 109.169 1.00 65.85  ? 88  LEU A N   1 
ATOM   670  C  CA  . LEU A 1 88  ? 144.589 144.740 107.987 1.00 61.49  ? 88  LEU A CA  1 
ATOM   671  C  C   . LEU A 1 88  ? 143.716 145.261 106.858 1.00 67.96  ? 88  LEU A C   1 
ATOM   672  O  O   . LEU A 1 88  ? 144.170 145.388 105.716 1.00 78.46  ? 88  LEU A O   1 
ATOM   673  C  CB  . LEU A 1 88  ? 144.221 143.297 108.334 1.00 55.42  ? 88  LEU A CB  1 
ATOM   674  C  CG  . LEU A 1 88  ? 144.387 142.255 107.226 1.00 58.30  ? 88  LEU A CG  1 
ATOM   675  C  CD1 . LEU A 1 88  ? 145.767 142.342 106.600 1.00 61.27  ? 88  LEU A CD1 1 
ATOM   676  C  CD2 . LEU A 1 88  ? 144.127 140.862 107.763 1.00 70.77  ? 88  LEU A CD2 1 
ATOM   677  N  N   . HIS A 1 89  ? 142.456 145.587 107.158 1.00 71.04  ? 89  HIS A N   1 
ATOM   678  C  CA  . HIS A 1 89  ? 141.565 146.055 106.101 1.00 68.67  ? 89  HIS A CA  1 
ATOM   679  C  C   . HIS A 1 89  ? 142.024 147.390 105.529 1.00 75.34  ? 89  HIS A C   1 
ATOM   680  O  O   . HIS A 1 89  ? 142.003 147.585 104.309 1.00 80.71  ? 89  HIS A O   1 
ATOM   681  C  CB  . HIS A 1 89  ? 140.130 146.163 106.607 1.00 69.57  ? 89  HIS A CB  1 
ATOM   682  C  CG  . HIS A 1 89  ? 139.155 146.537 105.538 1.00 76.16  ? 89  HIS A CG  1 
ATOM   683  N  ND1 . HIS A 1 89  ? 138.648 147.812 105.405 1.00 84.34  ? 89  HIS A ND1 1 
ATOM   684  C  CD2 . HIS A 1 89  ? 138.622 145.814 104.526 1.00 72.65  ? 89  HIS A CD2 1 
ATOM   685  C  CE1 . HIS A 1 89  ? 137.832 147.852 104.368 1.00 82.54  ? 89  HIS A CE1 1 
ATOM   686  N  NE2 . HIS A 1 89  ? 137.799 146.653 103.815 1.00 77.28  ? 89  HIS A NE2 1 
ATOM   687  N  N   . ARG A 1 90  ? 142.439 148.325 106.389 1.00 78.54  ? 90  ARG A N   1 
ATOM   688  C  CA  . ARG A 1 90  ? 142.883 149.622 105.892 1.00 75.61  ? 90  ARG A CA  1 
ATOM   689  C  C   . ARG A 1 90  ? 144.138 149.484 105.037 1.00 79.12  ? 90  ARG A C   1 
ATOM   690  O  O   . ARG A 1 90  ? 144.251 150.119 103.981 1.00 86.42  ? 90  ARG A O   1 
ATOM   691  C  CB  . ARG A 1 90  ? 143.124 150.579 107.059 1.00 74.12  ? 90  ARG A CB  1 
ATOM   692  C  CG  . ARG A 1 90  ? 141.846 151.054 107.719 1.00 77.43  ? 90  ARG A CG  1 
ATOM   693  C  CD  . ARG A 1 90  ? 142.113 152.033 108.846 1.00 78.07  ? 90  ARG A CD  1 
ATOM   694  N  NE  . ARG A 1 90  ? 140.871 152.489 109.456 1.00 77.50  ? 90  ARG A NE  1 
ATOM   695  C  CZ  . ARG A 1 90  ? 140.112 153.462 108.977 1.00 83.02  ? 90  ARG A CZ  1 
ATOM   696  N  NH1 . ARG A 1 90  ? 140.456 154.136 107.892 1.00 83.08  ? 90  ARG A NH1 1 
ATOM   697  N  NH2 . ARG A 1 90  ? 138.979 153.770 109.602 1.00 84.37  ? 90  ARG A NH2 1 
ATOM   698  N  N   . GLU A 1 91  ? 145.133 148.715 105.462 1.00 68.36  ? 91  GLU A N   1 
ATOM   699  C  CA  . GLU A 1 91  ? 146.366 148.460 104.681 1.00 68.76  ? 91  GLU A CA  1 
ATOM   700  C  C   . GLU A 1 91  ? 146.036 147.735 103.354 1.00 78.84  ? 91  GLU A C   1 
ATOM   701  O  O   . GLU A 1 91  ? 146.617 148.124 102.368 1.00 82.94  ? 91  GLU A O   1 
ATOM   702  C  CB  . GLU A 1 91  ? 147.419 147.801 105.586 1.00 75.10  ? 91  GLU A CB  1 
ATOM   703  C  CG  . GLU A 1 91  ? 148.854 147.806 105.115 1.00 85.11  ? 91  GLU A CG  1 
ATOM   704  C  CD  . GLU A 1 91  ? 149.703 146.720 105.766 1.00 93.89  ? 91  GLU A CD  1 
ATOM   705  O  OE1 . GLU A 1 91  ? 149.556 146.473 106.961 1.00 88.03  ? 91  GLU A OE1 1 
ATOM   706  O  OE2 . GLU A 1 91  ? 150.517 146.131 105.075 1.00 97.96  ? 91  GLU A OE2 1 
ATOM   707  N  N   . LEU A 1 92  ? 145.099 146.807 103.343 1.00 82.47  ? 92  LEU A N   1 
ATOM   708  C  CA  . LEU A 1 92  ? 144.701 146.108 102.095 1.00 73.70  ? 92  LEU A CA  1 
ATOM   709  C  C   . LEU A 1 92  ? 143.972 147.056 101.143 1.00 77.28  ? 92  LEU A C   1 
ATOM   710  O  O   . LEU A 1 92  ? 144.281 147.004 99.989  1.00 83.27  ? 92  LEU A O   1 
ATOM   711  C  CB  . LEU A 1 92  ? 143.917 144.825 102.407 1.00 73.61  ? 92  LEU A CB  1 
ATOM   712  C  CG  . LEU A 1 92  ? 144.648 143.726 103.165 1.00 77.29  ? 92  LEU A CG  1 
ATOM   713  C  CD1 . LEU A 1 92  ? 143.647 142.685 103.630 1.00 83.77  ? 92  LEU A CD1 1 
ATOM   714  C  CD2 . LEU A 1 92  ? 145.753 143.103 102.328 1.00 74.81  ? 92  LEU A CD2 1 
ATOM   715  N  N   . SER A 1 93  ? 143.148 147.952 101.650 1.00 80.52  ? 93  SER A N   1 
ATOM   716  C  CA  . SER A 1 93  ? 142.470 148.930 100.807 1.00 79.57  ? 93  SER A CA  1 
ATOM   717  C  C   . SER A 1 93  ? 143.453 149.945 100.241 1.00 80.61  ? 93  SER A C   1 
ATOM   718  O  O   . SER A 1 93  ? 143.370 150.312 99.062  1.00 85.80  ? 93  SER A O   1 
ATOM   719  C  CB  . SER A 1 93  ? 141.372 149.631 101.604 1.00 83.24  ? 93  SER A CB  1 
ATOM   720  O  OG  . SER A 1 93  ? 140.336 148.728 101.942 1.00 90.39  ? 93  SER A OG  1 
ATOM   721  N  N   . ALA A 1 94  ? 144.396 150.410 101.064 1.00 81.57  ? 94  ALA A N   1 
ATOM   722  C  CA  . ALA A 1 94  ? 145.399 151.348 100.575 1.00 87.08  ? 94  ALA A CA  1 
ATOM   723  C  C   . ALA A 1 94  ? 146.290 150.704 99.521  1.00 89.03  ? 94  ALA A C   1 
ATOM   724  O  O   . ALA A 1 94  ? 146.636 151.341 98.518  1.00 89.68  ? 94  ALA A O   1 
ATOM   725  C  CB  . ALA A 1 94  ? 146.232 151.881 101.739 1.00 87.62  ? 94  ALA A CB  1 
ATOM   726  N  N   . TRP A 1 95  ? 146.673 149.442 99.728  1.00 85.46  ? 95  TRP A N   1 
ATOM   727  C  CA  . TRP A 1 95  ? 147.479 148.731 98.739  1.00 81.23  ? 95  TRP A CA  1 
ATOM   728  C  C   . TRP A 1 95  ? 146.733 148.613 97.419  1.00 82.80  ? 95  TRP A C   1 
ATOM   729  O  O   . TRP A 1 95  ? 147.311 148.818 96.346  1.00 86.15  ? 95  TRP A O   1 
ATOM   730  C  CB  . TRP A 1 95  ? 147.851 147.344 99.272  1.00 86.87  ? 95  TRP A CB  1 
ATOM   731  C  CG  . TRP A 1 95  ? 148.896 146.609 98.470  1.00 86.40  ? 95  TRP A CG  1 
ATOM   732  C  CD1 . TRP A 1 95  ? 150.218 146.490 98.773  1.00 88.06  ? 95  TRP A CD1 1 
ATOM   733  C  CD2 . TRP A 1 95  ? 148.699 145.878 97.249  1.00 86.34  ? 95  TRP A CD2 1 
ATOM   734  N  NE1 . TRP A 1 95  ? 150.860 145.740 97.819  1.00 87.18  ? 95  TRP A NE1 1 
ATOM   735  C  CE2 . TRP A 1 95  ? 149.950 145.353 96.873  1.00 89.01  ? 95  TRP A CE2 1 
ATOM   736  C  CE3 . TRP A 1 95  ? 147.590 145.622 96.437  1.00 89.00  ? 95  TRP A CE3 1 
ATOM   737  C  CZ2 . TRP A 1 95  ? 150.122 144.587 95.723  1.00 92.93  ? 95  TRP A CZ2 1 
ATOM   738  C  CZ3 . TRP A 1 95  ? 147.764 144.860 95.296  1.00 90.71  ? 95  TRP A CZ3 1 
ATOM   739  C  CH2 . TRP A 1 95  ? 149.020 144.353 94.950  1.00 89.65  ? 95  TRP A CH2 1 
ATOM   740  N  N   . LEU A 1 96  ? 145.445 148.272 97.479  1.00 84.21  ? 96  LEU A N   1 
ATOM   741  C  CA  . LEU A 1 96  ? 144.657 148.142 96.259  1.00 83.37  ? 96  LEU A CA  1 
ATOM   742  C  C   . LEU A 1 96  ? 144.526 149.477 95.538  1.00 90.03  ? 96  LEU A C   1 
ATOM   743  O  O   . LEU A 1 96  ? 144.651 149.542 94.310  1.00 93.36  ? 96  LEU A O   1 
ATOM   744  C  CB  . LEU A 1 96  ? 143.279 147.568 96.585  1.00 84.63  ? 96  LEU A CB  1 
ATOM   745  C  CG  . LEU A 1 96  ? 143.243 146.064 96.860  1.00 88.91  ? 96  LEU A CG  1 
ATOM   746  C  CD1 . LEU A 1 96  ? 141.863 145.633 97.315  1.00 94.67  ? 96  LEU A CD1 1 
ATOM   747  C  CD2 . LEU A 1 96  ? 143.667 145.289 95.625  1.00 89.20  ? 96  LEU A CD2 1 
ATOM   748  N  N   . ASP A 1 97  ? 144.281 150.555 96.286  1.00 96.96  ? 97  ASP A N   1 
ATOM   749  C  CA  . ASP A 1 97  ? 144.170 151.872 95.667  1.00 94.47  ? 97  ASP A CA  1 
ATOM   750  C  C   . ASP A 1 97  ? 145.482 152.295 95.022  1.00 96.19  ? 97  ASP A C   1 
ATOM   751  O  O   . ASP A 1 97  ? 145.489 152.859 93.922  1.00 98.28  ? 97  ASP A O   1 
ATOM   752  C  CB  . ASP A 1 97  ? 143.727 152.906 96.701  1.00 98.73  ? 97  ASP A CB  1 
ATOM   753  C  CG  . ASP A 1 97  ? 142.222 152.994 96.824  1.00 107.88 ? 97  ASP A CG  1 
ATOM   754  O  OD1 . ASP A 1 97  ? 141.522 152.280 96.078  1.00 110.81 ? 97  ASP A OD1 1 
ATOM   755  O  OD2 . ASP A 1 97  ? 141.739 153.777 97.665  1.00 112.79 ? 97  ASP A OD2 1 
ATOM   756  N  N   . LEU A 1 98  ? 146.607 152.040 95.693  1.00 97.81  ? 98  LEU A N   1 
ATOM   757  C  CA  . LEU A 1 98  ? 147.900 152.408 95.128  1.00 97.35  ? 98  LEU A CA  1 
ATOM   758  C  C   . LEU A 1 98  ? 148.221 151.584 93.888  1.00 98.65  ? 98  LEU A C   1 
ATOM   759  O  O   . LEU A 1 98  ? 148.713 152.122 92.892  1.00 99.23  ? 98  LEU A O   1 
ATOM   760  C  CB  . LEU A 1 98  ? 148.997 152.244 96.179  1.00 97.49  ? 98  LEU A CB  1 
ATOM   761  C  CG  . LEU A 1 98  ? 149.113 153.372 97.202  1.00 101.84 ? 98  LEU A CG  1 
ATOM   762  C  CD1 . LEU A 1 98  ? 149.865 152.900 98.433  1.00 101.56 ? 98  LEU A CD1 1 
ATOM   763  C  CD2 . LEU A 1 98  ? 149.789 154.582 96.588  1.00 100.73 ? 98  LEU A CD2 1 
ATOM   764  N  N   . THR A 1 99  ? 147.949 150.277 93.929  1.00 95.72  ? 99  THR A N   1 
ATOM   765  C  CA  . THR A 1 99  ? 148.275 149.416 92.798  1.00 91.33  ? 99  THR A CA  1 
ATOM   766  C  C   . THR A 1 99  ? 147.379 149.690 91.599  1.00 95.68  ? 99  THR A C   1 
ATOM   767  O  O   . THR A 1 99  ? 147.837 149.592 90.455  1.00 100.41 ? 99  THR A O   1 
ATOM   768  C  CB  . THR A 1 99  ? 148.173 147.950 93.210  1.00 93.59  ? 99  THR A CB  1 
ATOM   769  O  OG1 . THR A 1 99  ? 148.796 147.771 94.487  1.00 95.25  ? 99  THR A OG1 1 
ATOM   770  C  CG2 . THR A 1 99  ? 148.861 147.061 92.193  1.00 92.76  ? 99  THR A CG2 1 
ATOM   771  N  N   . ALA A 1 100 ? 146.110 150.027 91.831  1.00 104.72 ? 100 ALA A N   1 
ATOM   772  C  CA  . ALA A 1 100 ? 145.226 150.358 90.722  1.00 106.21 ? 100 ALA A CA  1 
ATOM   773  C  C   . ALA A 1 100 ? 145.639 151.643 90.017  1.00 108.24 ? 100 ALA A C   1 
ATOM   774  O  O   . ALA A 1 100 ? 145.371 151.793 88.821  1.00 111.04 ? 100 ALA A O   1 
ATOM   775  C  CB  . ALA A 1 100 ? 143.785 150.473 91.213  1.00 109.13 ? 100 ALA A CB  1 
ATOM   776  N  N   . GLN A 1 101 ? 146.286 152.569 90.728  1.00 116.30 ? 101 GLN A N   1 
ATOM   777  C  CA  . GLN A 1 101 ? 146.707 153.822 90.112  1.00 117.36 ? 101 GLN A CA  1 
ATOM   778  C  C   . GLN A 1 101 ? 147.893 153.623 89.173  1.00 118.02 ? 101 GLN A C   1 
ATOM   779  O  O   . GLN A 1 101 ? 147.949 154.243 88.105  1.00 118.82 ? 101 GLN A O   1 
ATOM   780  C  CB  . GLN A 1 101 ? 147.056 154.845 91.193  1.00 119.05 ? 101 GLN A CB  1 
ATOM   781  C  CG  . GLN A 1 101 ? 145.850 155.530 91.811  1.00 119.03 ? 101 GLN A CG  1 
ATOM   782  C  CD  . GLN A 1 101 ? 145.363 156.708 90.993  1.00 120.34 ? 101 GLN A CD  1 
ATOM   783  O  OE1 . GLN A 1 101 ? 144.314 157.283 91.279  1.00 118.85 ? 101 GLN A OE1 1 
ATOM   784  N  NE2 . GLN A 1 101 ? 146.127 157.078 89.971  1.00 121.99 ? 101 GLN A NE2 1 
ATOM   785  N  N   . GLN A 1 102 ? 148.845 152.771 89.548  1.00 117.43 ? 102 GLN A N   1 
ATOM   786  C  CA  . GLN A 1 102 ? 150.029 152.559 88.723  1.00 118.80 ? 102 GLN A CA  1 
ATOM   787  C  C   . GLN A 1 102 ? 149.794 151.588 87.577  1.00 120.77 ? 102 GLN A C   1 
ATOM   788  O  O   . GLN A 1 102 ? 150.703 151.398 86.763  1.00 120.16 ? 102 GLN A O   1 
ATOM   789  C  CB  . GLN A 1 102 ? 151.192 152.061 89.583  1.00 117.38 ? 102 GLN A CB  1 
ATOM   790  C  CG  . GLN A 1 102 ? 151.182 152.577 91.005  1.00 118.25 ? 102 GLN A CG  1 
ATOM   791  C  CD  . GLN A 1 102 ? 152.167 151.848 91.896  1.00 121.10 ? 102 GLN A CD  1 
ATOM   792  O  OE1 . GLN A 1 102 ? 152.665 150.779 91.546  1.00 119.07 ? 102 GLN A OE1 1 
ATOM   793  N  NE2 . GLN A 1 102 ? 152.453 152.425 93.058  1.00 123.08 ? 102 GLN A NE2 1 
ATOM   794  N  N   . THR A 1 103 ? 148.621 150.976 87.489  1.00 121.81 ? 103 THR A N   1 
ATOM   795  C  CA  . THR A 1 103 ? 148.321 150.027 86.425  1.00 121.89 ? 103 THR A CA  1 
ATOM   796  C  C   . THR A 1 103 ? 147.243 150.512 85.472  1.00 121.97 ? 103 THR A C   1 
ATOM   797  O  O   . THR A 1 103 ? 147.338 150.263 84.268  1.00 121.17 ? 103 THR A O   1 
ATOM   798  C  CB  . THR A 1 103 ? 147.897 148.678 87.026  1.00 119.63 ? 103 THR A CB  1 
ATOM   799  O  OG1 . THR A 1 103 ? 148.661 148.422 88.209  1.00 121.73 ? 103 THR A OG1 1 
ATOM   800  C  CG2 . THR A 1 103 ? 148.128 147.557 86.029  1.00 119.54 ? 103 THR A CG2 1 
ATOM   801  N  N   . TYR A 1 104 ? 146.217 151.204 85.973  1.00 125.92 ? 104 TYR A N   1 
ATOM   802  C  CA  . TYR A 1 104 ? 145.139 151.696 85.126  1.00 126.60 ? 104 TYR A CA  1 
ATOM   803  C  C   . TYR A 1 104 ? 144.887 153.190 85.293  1.00 127.53 ? 104 TYR A C   1 
ATOM   804  O  O   . TYR A 1 104 ? 144.072 153.754 84.554  1.00 126.31 ? 104 TYR A O   1 
ATOM   805  C  CB  . TYR A 1 104 ? 143.846 150.920 85.395  1.00 124.29 ? 104 TYR A CB  1 
ATOM   806  C  CG  . TYR A 1 104 ? 144.053 149.433 85.571  1.00 125.49 ? 104 TYR A CG  1 
ATOM   807  C  CD1 . TYR A 1 104 ? 144.527 148.652 84.529  1.00 127.00 ? 104 TYR A CD1 1 
ATOM   808  C  CD2 . TYR A 1 104 ? 143.769 148.813 86.778  1.00 123.66 ? 104 TYR A CD2 1 
ATOM   809  C  CE1 . TYR A 1 104 ? 144.720 147.295 84.684  1.00 127.65 ? 104 TYR A CE1 1 
ATOM   810  C  CE2 . TYR A 1 104 ? 143.955 147.455 86.944  1.00 124.27 ? 104 TYR A CE2 1 
ATOM   811  C  CZ  . TYR A 1 104 ? 144.430 146.701 85.893  1.00 125.96 ? 104 TYR A CZ  1 
ATOM   812  O  OH  . TYR A 1 104 ? 144.618 145.348 86.052  1.00 121.13 ? 104 TYR A OH  1 
ATOM   813  N  N   . GLY A 1 105 ? 145.557 153.845 86.237  1.00 131.52 ? 105 GLY A N   1 
ATOM   814  C  CA  . GLY A 1 105 ? 145.393 155.273 86.415  1.00 131.83 ? 105 GLY A CA  1 
ATOM   815  C  C   . GLY A 1 105 ? 144.102 155.662 87.102  1.00 132.56 ? 105 GLY A C   1 
ATOM   816  O  O   . GLY A 1 105 ? 143.739 156.841 87.133  1.00 135.38 ? 105 GLY A O   1 
ATOM   817  N  N   . LYS A 1 106 ? 143.397 154.681 87.659  1.00 122.97 ? 106 LYS A N   1 
ATOM   818  C  CA  . LYS A 1 106 ? 142.149 154.915 88.368  1.00 121.32 ? 106 LYS A CA  1 
ATOM   819  C  C   . LYS A 1 106 ? 142.216 154.256 89.736  1.00 123.71 ? 106 LYS A C   1 
ATOM   820  O  O   . LYS A 1 106 ? 143.139 153.498 90.045  1.00 126.61 ? 106 LYS A O   1 
ATOM   821  C  CB  . LYS A 1 106 ? 140.943 154.383 87.583  1.00 120.07 ? 106 LYS A CB  1 
ATOM   822  C  CG  . LYS A 1 106 ? 141.021 154.603 86.084  1.00 122.00 ? 106 LYS A CG  1 
ATOM   823  C  CD  . LYS A 1 106 ? 139.679 154.350 85.423  1.00 123.17 ? 106 LYS A CD  1 
ATOM   824  C  CE  . LYS A 1 106 ? 139.666 153.014 84.706  1.00 123.59 ? 106 LYS A CE  1 
ATOM   825  N  NZ  . LYS A 1 106 ? 140.549 153.023 83.508  1.00 123.25 ? 106 LYS A NZ  1 
ATOM   826  N  N   . LYS A 1 107 ? 141.222 154.556 90.566  1.00 120.56 ? 107 LYS A N   1 
ATOM   827  C  CA  . LYS A 1 107 ? 141.133 153.971 91.896  1.00 119.07 ? 107 LYS A CA  1 
ATOM   828  C  C   . LYS A 1 107 ? 140.585 152.549 91.782  1.00 119.88 ? 107 LYS A C   1 
ATOM   829  O  O   . LYS A 1 107 ? 140.199 152.089 90.704  1.00 120.82 ? 107 LYS A O   1 
ATOM   830  C  CB  . LYS A 1 107 ? 140.275 154.850 92.803  1.00 119.96 ? 107 LYS A CB  1 
ATOM   831  C  CG  . LYS A 1 107 ? 140.566 156.335 92.679  1.00 121.59 ? 107 LYS A CG  1 
ATOM   832  C  CD  . LYS A 1 107 ? 141.766 156.742 93.519  1.00 121.93 ? 107 LYS A CD  1 
ATOM   833  C  CE  . LYS A 1 107 ? 141.674 156.183 94.928  1.00 120.80 ? 107 LYS A CE  1 
ATOM   834  N  NZ  . LYS A 1 107 ? 140.747 156.980 95.778  1.00 119.37 ? 107 LYS A NZ  1 
ATOM   835  N  N   . PHE A 1 108 ? 140.550 151.830 92.905  1.00 115.56 ? 108 PHE A N   1 
ATOM   836  C  CA  . PHE A 1 108 ? 140.056 150.458 92.894  1.00 113.76 ? 108 PHE A CA  1 
ATOM   837  C  C   . PHE A 1 108 ? 138.570 150.396 92.560  1.00 119.14 ? 108 PHE A C   1 
ATOM   838  O  O   . PHE A 1 108 ? 138.125 149.473 91.870  1.00 121.93 ? 108 PHE A O   1 
ATOM   839  C  CB  . PHE A 1 108 ? 140.321 149.795 94.245  1.00 112.38 ? 108 PHE A CB  1 
ATOM   840  C  CG  . PHE A 1 108 ? 140.021 148.326 94.267  1.00 113.80 ? 108 PHE A CG  1 
ATOM   841  C  CD1 . PHE A 1 108 ? 140.661 147.463 93.397  1.00 114.64 ? 108 PHE A CD1 1 
ATOM   842  C  CD2 . PHE A 1 108 ? 139.088 147.810 95.151  1.00 115.80 ? 108 PHE A CD2 1 
ATOM   843  C  CE1 . PHE A 1 108 ? 140.387 146.111 93.414  1.00 115.20 ? 108 PHE A CE1 1 
ATOM   844  C  CE2 . PHE A 1 108 ? 138.809 146.459 95.171  1.00 115.27 ? 108 PHE A CE2 1 
ATOM   845  C  CZ  . PHE A 1 108 ? 139.459 145.609 94.301  1.00 114.10 ? 108 PHE A CZ  1 
ATOM   846  N  N   . ASP A 1 109 ? 137.789 151.365 93.047  1.00 139.67 ? 109 ASP A N   1 
ATOM   847  C  CA  . ASP A 1 109 ? 136.345 151.326 92.846  1.00 139.38 ? 109 ASP A CA  1 
ATOM   848  C  C   . ASP A 1 109 ? 135.973 151.545 91.384  1.00 138.82 ? 109 ASP A C   1 
ATOM   849  O  O   . ASP A 1 109 ? 135.106 150.847 90.845  1.00 139.81 ? 109 ASP A O   1 
ATOM   850  C  CB  . ASP A 1 109 ? 135.666 152.368 93.732  1.00 140.93 ? 109 ASP A CB  1 
ATOM   851  C  CG  . ASP A 1 109 ? 135.487 151.890 95.158  1.00 143.83 ? 109 ASP A CG  1 
ATOM   852  O  OD1 . ASP A 1 109 ? 135.995 150.797 95.487  1.00 141.44 ? 109 ASP A OD1 1 
ATOM   853  O  OD2 . ASP A 1 109 ? 134.840 152.606 95.950  1.00 146.19 ? 109 ASP A OD2 1 
ATOM   854  N  N   . GLU A 1 110 ? 136.611 152.513 90.726  1.00 134.63 ? 110 GLU A N   1 
ATOM   855  C  CA  . GLU A 1 110 ? 136.292 152.811 89.335  1.00 136.15 ? 110 GLU A CA  1 
ATOM   856  C  C   . GLU A 1 110 ? 137.112 151.944 88.389  1.00 137.58 ? 110 GLU A C   1 
ATOM   857  O  O   . GLU A 1 110 ? 137.735 152.445 87.449  1.00 136.22 ? 110 GLU A O   1 
ATOM   858  C  CB  . GLU A 1 110 ? 136.510 154.298 89.047  1.00 136.51 ? 110 GLU A CB  1 
ATOM   859  C  CG  . GLU A 1 110 ? 137.876 154.823 89.452  1.00 138.02 ? 110 GLU A CG  1 
ATOM   860  C  CD  . GLU A 1 110 ? 137.807 156.198 90.082  1.00 142.40 ? 110 GLU A CD  1 
ATOM   861  O  OE1 . GLU A 1 110 ? 136.846 156.459 90.835  1.00 142.23 ? 110 GLU A OE1 1 
ATOM   862  O  OE2 . GLU A 1 110 ? 138.713 157.019 89.826  1.00 143.39 ? 110 GLU A OE2 1 
ATOM   863  N  N   . VAL A 1 111 ? 137.212 150.648 88.646  1.00 135.64 ? 111 VAL A N   1 
ATOM   864  C  CA  . VAL A 1 111 ? 137.946 149.712 87.737  1.00 133.80 ? 111 VAL A CA  1 
ATOM   865  C  C   . VAL A 1 111 ? 137.007 148.526 87.586  1.00 135.86 ? 111 VAL A C   1 
ATOM   866  O  O   . VAL A 1 111 ? 136.321 148.229 88.561  1.00 135.77 ? 111 VAL A O   1 
ATOM   867  C  CB  . VAL A 1 111 ? 139.362 149.312 88.228  1.00 132.31 ? 111 VAL A CB  1 
ATOM   868  C  CG1 . VAL A 1 111 ? 139.566 147.816 88.354  1.00 132.24 ? 111 VAL A CG1 1 
ATOM   869  C  CG2 . VAL A 1 111 ? 140.479 149.957 87.429  1.00 128.49 ? 111 VAL A CG2 1 
ATOM   870  N  N   . SER A 1 112 ? 136.941 147.907 86.416  1.00 131.85 ? 112 SER A N   1 
ATOM   871  C  CA  . SER A 1 112 ? 136.027 146.824 86.088  1.00 129.35 ? 112 SER A CA  1 
ATOM   872  C  C   . SER A 1 112 ? 136.353 145.579 86.911  1.00 133.47 ? 112 SER A C   1 
ATOM   873  O  O   . SER A 1 112 ? 137.509 145.359 87.288  1.00 135.12 ? 112 SER A O   1 
ATOM   874  C  CB  . SER A 1 112 ? 136.097 146.501 84.597  1.00 129.54 ? 112 SER A CB  1 
ATOM   875  O  OG  . SER A 1 112 ? 137.247 145.736 84.291  1.00 130.61 ? 112 SER A OG  1 
ATOM   876  N  N   . PRO A 1 113 ? 135.349 144.753 87.218  1.00 127.14 ? 113 PRO A N   1 
ATOM   877  C  CA  . PRO A 1 113 ? 135.606 143.566 88.053  1.00 127.88 ? 113 PRO A CA  1 
ATOM   878  C  C   . PRO A 1 113 ? 136.595 142.590 87.446  1.00 129.94 ? 113 PRO A C   1 
ATOM   879  O  O   . PRO A 1 113 ? 137.263 141.862 88.190  1.00 129.18 ? 113 PRO A O   1 
ATOM   880  C  CB  . PRO A 1 113 ? 134.213 142.938 88.207  1.00 121.98 ? 113 PRO A CB  1 
ATOM   881  C  CG  . PRO A 1 113 ? 133.397 143.514 87.096  1.00 122.69 ? 113 PRO A CG  1 
ATOM   882  C  CD  . PRO A 1 113 ? 133.925 144.892 86.876  1.00 121.59 ? 113 PRO A CD  1 
ATOM   883  N  N   . GLU A 1 114 ? 136.730 142.564 86.117  1.00 134.54 ? 114 GLU A N   1 
ATOM   884  C  CA  . GLU A 1 114 ? 137.682 141.654 85.490  1.00 130.97 ? 114 GLU A CA  1 
ATOM   885  C  C   . GLU A 1 114 ? 139.106 141.943 85.949  1.00 130.30 ? 114 GLU A C   1 
ATOM   886  O  O   . GLU A 1 114 ? 139.869 141.018 86.250  1.00 132.08 ? 114 GLU A O   1 
ATOM   887  C  CB  . GLU A 1 114 ? 137.582 141.750 83.969  1.00 131.11 ? 114 GLU A CB  1 
ATOM   888  C  CG  . GLU A 1 114 ? 136.353 141.078 83.375  1.00 132.94 ? 114 GLU A CG  1 
ATOM   889  C  CD  . GLU A 1 114 ? 135.090 141.895 83.559  1.00 135.03 ? 114 GLU A CD  1 
ATOM   890  O  OE1 . GLU A 1 114 ? 134.404 141.708 84.586  1.00 137.64 ? 114 GLU A OE1 1 
ATOM   891  O  OE2 . GLU A 1 114 ? 134.783 142.726 82.680  1.00 134.38 ? 114 GLU A OE2 1 
ATOM   892  N  N   . GLU A 1 115 ? 139.481 143.220 86.012  1.00 124.12 ? 115 GLU A N   1 
ATOM   893  C  CA  . GLU A 1 115 ? 140.792 143.596 86.521  1.00 128.23 ? 115 GLU A CA  1 
ATOM   894  C  C   . GLU A 1 115 ? 140.810 143.771 88.034  1.00 127.64 ? 115 GLU A C   1 
ATOM   895  O  O   . GLU A 1 115 ? 141.889 143.713 88.639  1.00 127.75 ? 115 GLU A O   1 
ATOM   896  C  CB  . GLU A 1 115 ? 141.275 144.876 85.835  1.00 127.73 ? 115 GLU A CB  1 
ATOM   897  C  CG  . GLU A 1 115 ? 140.163 145.835 85.475  1.00 127.73 ? 115 GLU A CG  1 
ATOM   898  C  CD  . GLU A 1 115 ? 140.566 146.823 84.399  1.00 131.12 ? 115 GLU A CD  1 
ATOM   899  O  OE1 . GLU A 1 115 ? 141.756 146.855 84.035  1.00 127.98 ? 115 GLU A OE1 1 
ATOM   900  O  OE2 . GLU A 1 115 ? 139.688 147.574 83.922  1.00 132.03 ? 115 GLU A OE2 1 
ATOM   901  N  N   . GLN A 1 116 ? 139.647 143.953 88.662  1.00 119.71 ? 116 GLN A N   1 
ATOM   902  C  CA  . GLN A 1 116 ? 139.586 143.897 90.118  1.00 117.60 ? 116 GLN A CA  1 
ATOM   903  C  C   . GLN A 1 116 ? 139.988 142.519 90.622  1.00 121.36 ? 116 GLN A C   1 
ATOM   904  O  O   . GLN A 1 116 ? 140.670 142.395 91.645  1.00 125.59 ? 116 GLN A O   1 
ATOM   905  C  CB  . GLN A 1 116 ? 138.183 144.252 90.609  1.00 115.25 ? 116 GLN A CB  1 
ATOM   906  C  CG  . GLN A 1 116 ? 137.846 145.727 90.541  1.00 118.96 ? 116 GLN A CG  1 
ATOM   907  C  CD  . GLN A 1 116 ? 136.729 146.108 91.487  1.00 121.65 ? 116 GLN A CD  1 
ATOM   908  O  OE1 . GLN A 1 116 ? 136.028 145.246 92.014  1.00 121.85 ? 116 GLN A OE1 1 
ATOM   909  N  NE2 . GLN A 1 116 ? 136.555 147.404 91.706  1.00 120.96 ? 116 GLN A NE2 1 
ATOM   910  N  N   . ALA A 1 117 ? 139.569 141.468 89.916  1.00 121.73 ? 117 ALA A N   1 
ATOM   911  C  CA  . ALA A 1 117 ? 139.977 140.115 90.278  1.00 120.57 ? 117 ALA A CA  1 
ATOM   912  C  C   . ALA A 1 117 ? 141.486 139.939 90.150  1.00 122.76 ? 117 ALA A C   1 
ATOM   913  O  O   . ALA A 1 117 ? 142.116 139.286 90.991  1.00 122.56 ? 117 ALA A O   1 
ATOM   914  C  CB  . ALA A 1 117 ? 139.241 139.096 89.409  1.00 120.66 ? 117 ALA A CB  1 
ATOM   915  N  N   . VAL A 1 118 ? 142.081 140.504 89.097  1.00 118.35 ? 118 VAL A N   1 
ATOM   916  C  CA  . VAL A 1 118 ? 143.529 140.429 88.921  1.00 117.54 ? 118 VAL A CA  1 
ATOM   917  C  C   . VAL A 1 118 ? 144.244 141.148 90.060  1.00 119.33 ? 118 VAL A C   1 
ATOM   918  O  O   . VAL A 1 118 ? 145.216 140.637 90.629  1.00 121.08 ? 118 VAL A O   1 
ATOM   919  C  CB  . VAL A 1 118 ? 143.929 141.007 87.552  1.00 112.96 ? 118 VAL A CB  1 
ATOM   920  C  CG1 . VAL A 1 118 ? 145.439 141.071 87.419  1.00 115.65 ? 118 VAL A CG1 1 
ATOM   921  C  CG2 . VAL A 1 118 ? 143.323 140.181 86.432  1.00 113.39 ? 118 VAL A CG2 1 
ATOM   922  N  N   . LEU A 1 119 ? 143.769 142.344 90.409  1.00 108.26 ? 119 LEU A N   1 
ATOM   923  C  CA  . LEU A 1 119 ? 144.372 143.079 91.515  1.00 105.92 ? 119 LEU A CA  1 
ATOM   924  C  C   . LEU A 1 119 ? 144.247 142.308 92.822  1.00 109.07 ? 119 LEU A C   1 
ATOM   925  O  O   . LEU A 1 119 ? 145.195 142.248 93.612  1.00 112.86 ? 119 LEU A O   1 
ATOM   926  C  CB  . LEU A 1 119 ? 143.725 144.456 91.640  1.00 105.41 ? 119 LEU A CB  1 
ATOM   927  C  CG  . LEU A 1 119 ? 144.157 145.508 90.616  1.00 107.13 ? 119 LEU A CG  1 
ATOM   928  C  CD1 . LEU A 1 119 ? 143.414 146.809 90.851  1.00 111.43 ? 119 LEU A CD1 1 
ATOM   929  C  CD2 . LEU A 1 119 ? 145.657 145.727 90.662  1.00 107.24 ? 119 LEU A CD2 1 
ATOM   930  N  N   . LYS A 1 120 ? 143.084 141.701 93.062  1.00 108.07 ? 120 LYS A N   1 
ATOM   931  C  CA  . LYS A 1 120 ? 142.868 140.946 94.289  1.00 106.53 ? 120 LYS A CA  1 
ATOM   932  C  C   . LYS A 1 120 ? 143.740 139.700 94.366  1.00 110.08 ? 120 LYS A C   1 
ATOM   933  O  O   . LYS A 1 120 ? 144.261 139.388 95.440  1.00 115.36 ? 120 LYS A O   1 
ATOM   934  C  CB  . LYS A 1 120 ? 141.392 140.570 94.423  1.00 105.74 ? 120 LYS A CB  1 
ATOM   935  C  CG  . LYS A 1 120 ? 140.586 141.553 95.254  1.00 107.32 ? 120 LYS A CG  1 
ATOM   936  C  CD  . LYS A 1 120 ? 139.276 140.946 95.721  1.00 105.88 ? 120 LYS A CD  1 
ATOM   937  C  CE  . LYS A 1 120 ? 138.309 140.765 94.569  1.00 112.19 ? 120 LYS A CE  1 
ATOM   938  N  NZ  . LYS A 1 120 ? 137.409 141.938 94.422  1.00 111.87 ? 120 LYS A NZ  1 
ATOM   939  N  N   . THR A 1 121 ? 143.984 139.051 93.243  1.00 102.98 ? 121 THR A N   1 
ATOM   940  C  CA  . THR A 1 121 ? 144.822 137.838 93.153  1.00 104.64 ? 121 THR A CA  1 
ATOM   941  C  C   . THR A 1 121 ? 146.255 138.244 93.463  1.00 105.72 ? 121 THR A C   1 
ATOM   942  O  O   . THR A 1 121 ? 146.949 137.576 94.220  1.00 107.13 ? 121 THR A O   1 
ATOM   943  C  CB  . THR A 1 121 ? 144.671 137.159 91.782  1.00 102.55 ? 121 THR A CB  1 
ATOM   944  O  OG1 . THR A 1 121 ? 145.024 135.787 91.907  1.00 107.77 ? 121 THR A OG1 1 
ATOM   945  C  CG2 . THR A 1 121 ? 145.560 137.742 90.712  1.00 99.74  ? 121 THR A CG2 1 
ATOM   946  N  N   . ARG A 1 122 ? 146.773 139.305 92.838  1.00 104.04 ? 122 ARG A N   1 
ATOM   947  C  CA  . ARG A 1 122 ? 148.119 139.895 93.116  1.00 102.23 ? 122 ARG A CA  1 
ATOM   948  C  C   . ARG A 1 122 ? 148.282 140.326 94.578  1.00 101.40 ? 122 ARG A C   1 
ATOM   949  O  O   . ARG A 1 122 ? 149.357 140.161 95.099  1.00 102.10 ? 122 ARG A O   1 
ATOM   950  C  CB  . ARG A 1 122 ? 148.401 141.071 92.186  1.00 98.54  ? 122 ARG A CB  1 
ATOM   951  C  CG  . ARG A 1 122 ? 148.796 140.692 90.770  1.00 100.90 ? 122 ARG A CG  1 
ATOM   952  C  CD  . ARG A 1 122 ? 148.777 141.938 89.914  1.00 103.87 ? 122 ARG A CD  1 
ATOM   953  N  NE  . ARG A 1 122 ? 149.757 142.913 90.363  1.00 108.14 ? 122 ARG A NE  1 
ATOM   954  C  CZ  . ARG A 1 122 ? 149.858 144.151 89.900  1.00 109.98 ? 122 ARG A CZ  1 
ATOM   955  N  NH1 . ARG A 1 122 ? 150.864 144.916 90.279  1.00 107.26 ? 122 ARG A NH1 1 
ATOM   956  N  NH2 . ARG A 1 122 ? 148.948 144.624 89.070  1.00 107.66 ? 122 ARG A NH2 1 
ATOM   957  N  N   . LEU A 1 123 ? 147.228 140.812 95.204  1.00 94.08  ? 123 LEU A N   1 
ATOM   958  C  CA  . LEU A 1 123 ? 147.290 141.174 96.635  1.00 92.72  ? 123 LEU A CA  1 
ATOM   959  C  C   . LEU A 1 123 ? 147.362 139.910 97.473  1.00 94.37  ? 123 LEU A C   1 
ATOM   960  O  O   . LEU A 1 123 ? 148.125 139.863 98.414  1.00 104.61 ? 123 LEU A O   1 
ATOM   961  C  CB  . LEU A 1 123 ? 146.032 141.966 96.973  1.00 92.35  ? 123 LEU A CB  1 
ATOM   962  C  CG  . LEU A 1 123 ? 145.759 142.281 98.437  1.00 90.33  ? 123 LEU A CG  1 
ATOM   963  C  CD1 . LEU A 1 123 ? 146.409 143.591 98.832  1.00 96.22  ? 123 LEU A CD1 1 
ATOM   964  C  CD2 . LEU A 1 123 ? 144.263 142.351 98.682  1.00 94.25  ? 123 LEU A CD2 1 
ATOM   965  N  N   . ALA A 1 124 ? 146.552 138.930 97.141  1.00 86.79  ? 124 ALA A N   1 
ATOM   966  C  CA  . ALA A 1 124 ? 146.564 137.699 97.922  1.00 89.48  ? 124 ALA A CA  1 
ATOM   967  C  C   . ALA A 1 124 ? 147.905 136.988 97.813  1.00 98.28  ? 124 ALA A C   1 
ATOM   968  O  O   . ALA A 1 124 ? 148.423 136.471 98.812  1.00 100.54 ? 124 ALA A O   1 
ATOM   969  C  CB  . ALA A 1 124 ? 145.429 136.781 97.471  1.00 93.26  ? 124 ALA A CB  1 
ATOM   970  N  N   . ASP A 1 125 ? 148.482 136.945 96.613  1.00 114.51 ? 125 ASP A N   1 
ATOM   971  C  CA  . ASP A 1 125 ? 149.785 136.309 96.453  1.00 115.07 ? 125 ASP A CA  1 
ATOM   972  C  C   . ASP A 1 125 ? 150.866 137.067 97.213  1.00 115.16 ? 125 ASP A C   1 
ATOM   973  O  O   . ASP A 1 125 ? 151.721 136.458 97.865  1.00 112.41 ? 125 ASP A O   1 
ATOM   974  C  CB  . ASP A 1 125 ? 150.148 136.200 94.974  1.00 116.37 ? 125 ASP A CB  1 
ATOM   975  C  CG  . ASP A 1 125 ? 151.409 135.394 94.746  1.00 119.65 ? 125 ASP A CG  1 
ATOM   976  O  OD1 . ASP A 1 125 ? 151.403 134.184 95.051  1.00 120.99 ? 125 ASP A OD1 1 
ATOM   977  O  OD2 . ASP A 1 125 ? 152.408 135.970 94.273  1.00 116.50 ? 125 ASP A OD2 1 
ATOM   978  N  N   . GLU A 1 126 ? 150.851 138.400 97.134  1.00 111.68 ? 126 GLU A N   1 
ATOM   979  C  CA  . GLU A 1 126 ? 151.890 139.174 97.803  1.00 108.31 ? 126 GLU A CA  1 
ATOM   980  C  C   . GLU A 1 126 ? 151.795 139.065 99.319  1.00 101.25 ? 126 GLU A C   1 
ATOM   981  O  O   . GLU A 1 126 ? 152.820 138.937 99.997  1.00 106.78 ? 126 GLU A O   1 
ATOM   982  C  CB  . GLU A 1 126 ? 151.820 140.640 97.373  1.00 106.24 ? 126 GLU A CB  1 
ATOM   983  C  CG  . GLU A 1 126 ? 152.451 141.600 98.363  1.00 108.23 ? 126 GLU A CG  1 
ATOM   984  C  CD  . GLU A 1 126 ? 152.983 142.853 97.704  1.00 113.44 ? 126 GLU A CD  1 
ATOM   985  O  OE1 . GLU A 1 126 ? 152.844 143.942 98.298  1.00 118.91 ? 126 GLU A OE1 1 
ATOM   986  O  OE2 . GLU A 1 126 ? 153.541 142.749 96.593  1.00 115.22 ? 126 GLU A OE2 1 
ATOM   987  N  N   . TYR A 1 127 ? 150.583 139.100 99.871  1.00 81.35  ? 127 TYR A N   1 
ATOM   988  C  CA  . TYR A 1 127 ? 150.438 139.173 101.322 1.00 81.83  ? 127 TYR A CA  1 
ATOM   989  C  C   . TYR A 1 127 ? 150.612 137.809 101.984 1.00 90.94  ? 127 TYR A C   1 
ATOM   990  O  O   . TYR A 1 127 ? 151.236 137.699 103.043 1.00 96.90  ? 127 TYR A O   1 
ATOM   991  C  CB  . TYR A 1 127 ? 149.081 139.783 101.680 1.00 78.13  ? 127 TYR A CB  1 
ATOM   992  C  CG  . TYR A 1 127 ? 149.161 141.253 102.008 1.00 84.50  ? 127 TYR A CG  1 
ATOM   993  C  CD1 . TYR A 1 127 ? 149.429 142.189 101.019 1.00 90.72  ? 127 TYR A CD1 1 
ATOM   994  C  CD2 . TYR A 1 127 ? 148.972 141.708 103.304 1.00 83.57  ? 127 TYR A CD2 1 
ATOM   995  C  CE1 . TYR A 1 127 ? 149.508 143.531 101.309 1.00 86.59  ? 127 TYR A CE1 1 
ATOM   996  C  CE2 . TYR A 1 127 ? 149.048 143.051 103.604 1.00 86.06  ? 127 TYR A CE2 1 
ATOM   997  C  CZ  . TYR A 1 127 ? 149.315 143.957 102.602 1.00 85.46  ? 127 TYR A CZ  1 
ATOM   998  O  OH  . TYR A 1 127 ? 149.391 145.298 102.892 1.00 89.05  ? 127 TYR A OH  1 
ATOM   999  N  N   . ARG A 1 128 ? 150.061 136.755 101.380 1.00 88.11  ? 128 ARG A N   1 
ATOM   1000 C  CA  . ARG A 1 128 ? 150.083 135.446 102.024 1.00 80.72  ? 128 ARG A CA  1 
ATOM   1001 C  C   . ARG A 1 128 ? 151.358 134.658 101.752 1.00 83.68  ? 128 ARG A C   1 
ATOM   1002 O  O   . ARG A 1 128 ? 151.813 133.928 102.638 1.00 83.68  ? 128 ARG A O   1 
ATOM   1003 C  CB  . ARG A 1 128 ? 148.872 134.616 101.593 1.00 77.92  ? 128 ARG A CB  1 
ATOM   1004 C  CG  . ARG A 1 128 ? 147.537 135.323 101.750 1.00 81.91  ? 128 ARG A CG  1 
ATOM   1005 C  CD  . ARG A 1 128 ? 146.408 134.482 101.182 1.00 80.05  ? 128 ARG A CD  1 
ATOM   1006 N  NE  . ARG A 1 128 ? 146.230 133.250 101.939 1.00 80.77  ? 128 ARG A NE  1 
ATOM   1007 C  CZ  . ARG A 1 128 ? 145.448 133.126 103.001 1.00 82.21  ? 128 ARG A CZ  1 
ATOM   1008 N  NH1 . ARG A 1 128 ? 144.719 134.138 103.443 1.00 79.46  ? 128 ARG A NH1 1 
ATOM   1009 N  NH2 . ARG A 1 128 ? 145.396 131.961 103.637 1.00 85.67  ? 128 ARG A NH2 1 
ATOM   1010 N  N   . ASN A 1 129 ? 151.944 134.782 100.566 1.00 101.48 ? 129 ASN A N   1 
ATOM   1011 C  CA  . ASN A 1 129 ? 153.092 133.969 100.182 1.00 101.62 ? 129 ASN A CA  1 
ATOM   1012 C  C   . ASN A 1 129 ? 154.415 134.712 100.216 1.00 102.83 ? 129 ASN A C   1 
ATOM   1013 O  O   . ASN A 1 129 ? 155.399 134.182 100.731 1.00 109.42 ? 129 ASN A O   1 
ATOM   1014 C  CB  . ASN A 1 129 ? 152.883 133.392 98.778  1.00 106.22 ? 129 ASN A CB  1 
ATOM   1015 C  CG  . ASN A 1 129 ? 151.644 132.529 98.683  1.00 111.49 ? 129 ASN A CG  1 
ATOM   1016 O  OD1 . ASN A 1 129 ? 151.480 131.577 99.444  1.00 111.87 ? 129 ASN A OD1 1 
ATOM   1017 N  ND2 . ASN A 1 129 ? 150.764 132.854 97.745  1.00 110.02 ? 129 ASN A ND2 1 
ATOM   1018 N  N   . GLN A 1 130 ? 154.473 135.929 99.682  1.00 96.26  ? 130 GLN A N   1 
ATOM   1019 C  CA  . GLN A 1 130 ? 155.731 136.659 99.600  1.00 96.54  ? 130 GLN A CA  1 
ATOM   1020 C  C   . GLN A 1 130 ? 156.159 137.264 100.930 1.00 97.39  ? 130 GLN A C   1 
ATOM   1021 O  O   . GLN A 1 130 ? 157.306 137.707 101.045 1.00 100.05 ? 130 GLN A O   1 
ATOM   1022 C  CB  . GLN A 1 130 ? 155.630 137.762 98.546  1.00 93.67  ? 130 GLN A CB  1 
ATOM   1023 C  CG  . GLN A 1 130 ? 155.405 137.247 97.141  1.00 97.16  ? 130 GLN A CG  1 
ATOM   1024 C  CD  . GLN A 1 130 ? 155.318 138.363 96.124  1.00 104.03 ? 130 GLN A CD  1 
ATOM   1025 O  OE1 . GLN A 1 130 ? 155.897 139.430 96.307  1.00 107.22 ? 130 GLN A OE1 1 
ATOM   1026 N  NE2 . GLN A 1 130 ? 154.591 138.120 95.041  1.00 100.05 ? 130 GLN A NE2 1 
ATOM   1027 N  N   . SER A 1 131 ? 155.279 137.289 101.930 1.00 98.53  ? 131 SER A N   1 
ATOM   1028 C  CA  . SER A 1 131 ? 155.583 137.885 103.224 1.00 92.41  ? 131 SER A CA  1 
ATOM   1029 C  C   . SER A 1 131 ? 156.007 136.845 104.253 1.00 96.08  ? 131 SER A C   1 
ATOM   1030 O  O   . SER A 1 131 ? 156.133 137.169 105.438 1.00 99.89  ? 131 SER A O   1 
ATOM   1031 C  CB  . SER A 1 131 ? 154.381 138.680 103.734 1.00 90.28  ? 131 SER A CB  1 
ATOM   1032 O  OG  . SER A 1 131 ? 154.223 139.879 103.000 1.00 95.24  ? 131 SER A OG  1 
ATOM   1033 N  N   . ARG A 1 132 ? 156.222 135.604 103.827 1.00 98.38  ? 132 ARG A N   1 
ATOM   1034 C  CA  . ARG A 1 132 ? 156.668 134.566 104.746 1.00 96.73  ? 132 ARG A CA  1 
ATOM   1035 C  C   . ARG A 1 132 ? 158.039 134.910 105.311 1.00 99.34  ? 132 ARG A C   1 
ATOM   1036 O  O   . ARG A 1 132 ? 158.884 135.504 104.636 1.00 97.66  ? 132 ARG A O   1 
ATOM   1037 C  CB  . ARG A 1 132 ? 156.723 133.211 104.041 1.00 96.13  ? 132 ARG A CB  1 
ATOM   1038 C  CG  . ARG A 1 132 ? 155.371 132.655 103.641 1.00 99.29  ? 132 ARG A CG  1 
ATOM   1039 C  CD  . ARG A 1 132 ? 155.531 131.423 102.773 1.00 101.60 ? 132 ARG A CD  1 
ATOM   1040 N  NE  . ARG A 1 132 ? 154.676 130.327 103.209 1.00 103.65 ? 132 ARG A NE  1 
ATOM   1041 C  CZ  . ARG A 1 132 ? 153.852 129.660 102.413 1.00 104.89 ? 132 ARG A CZ  1 
ATOM   1042 N  NH1 . ARG A 1 132 ? 153.751 129.946 101.126 1.00 103.07 ? 132 ARG A NH1 1 
ATOM   1043 N  NH2 . ARG A 1 132 ? 153.112 128.679 102.920 1.00 102.44 ? 132 ARG A NH2 1 
ATOM   1044 N  N   . ILE A 1 133 ? 158.254 134.538 106.573 1.00 96.80  ? 133 ILE A N   1 
ATOM   1045 C  CA  . ILE A 1 133 ? 159.531 134.814 107.215 1.00 93.98  ? 133 ILE A CA  1 
ATOM   1046 C  C   . ILE A 1 133 ? 160.627 133.989 106.551 1.00 101.27 ? 133 ILE A C   1 
ATOM   1047 O  O   . ILE A 1 133 ? 160.385 132.903 106.008 1.00 107.17 ? 133 ILE A O   1 
ATOM   1048 C  CB  . ILE A 1 133 ? 159.452 134.546 108.730 1.00 89.24  ? 133 ILE A CB  1 
ATOM   1049 C  CG1 . ILE A 1 133 ? 160.383 135.502 109.481 1.00 96.73  ? 133 ILE A CG1 1 
ATOM   1050 C  CG2 . ILE A 1 133 ? 159.768 133.096 109.050 1.00 90.34  ? 133 ILE A CG2 1 
ATOM   1051 C  CD1 . ILE A 1 133 ? 160.325 135.360 110.977 1.00 94.96  ? 133 ILE A CD1 1 
ATOM   1052 N  N   . LYS A 1 134 ? 161.843 134.520 106.572 1.00 99.69  ? 134 LYS A N   1 
ATOM   1053 C  CA  . LYS A 1 134 ? 162.959 133.925 105.859 1.00 97.75  ? 134 LYS A CA  1 
ATOM   1054 C  C   . LYS A 1 134 ? 163.875 133.181 106.824 1.00 105.36 ? 134 LYS A C   1 
ATOM   1055 O  O   . LYS A 1 134 ? 163.632 133.110 108.031 1.00 108.73 ? 134 LYS A O   1 
ATOM   1056 C  CB  . LYS A 1 134 ? 163.723 135.001 105.086 1.00 96.45  ? 134 LYS A CB  1 
ATOM   1057 C  CG  . LYS A 1 134 ? 162.851 135.809 104.148 1.00 101.08 ? 134 LYS A CG  1 
ATOM   1058 C  CD  . LYS A 1 134 ? 163.645 136.892 103.452 1.00 103.27 ? 134 LYS A CD  1 
ATOM   1059 C  CE  . LYS A 1 134 ? 163.429 136.853 101.949 1.00 104.02 ? 134 LYS A CE  1 
ATOM   1060 N  NZ  . LYS A 1 134 ? 162.028 136.498 101.595 1.00 100.91 ? 134 LYS A NZ  1 
ATOM   1061 N  N   . GLU A 1 135 ? 164.950 132.612 106.271 1.00 127.88 ? 135 GLU A N   1 
ATOM   1062 C  CA  . GLU A 1 135 ? 165.888 131.838 107.081 1.00 127.53 ? 135 GLU A CA  1 
ATOM   1063 C  C   . GLU A 1 135 ? 166.563 132.704 108.134 1.00 127.15 ? 135 GLU A C   1 
ATOM   1064 O  O   . GLU A 1 135 ? 166.731 132.281 109.282 1.00 124.59 ? 135 GLU A O   1 
ATOM   1065 C  CB  . GLU A 1 135 ? 166.933 131.177 106.178 1.00 130.50 ? 135 GLU A CB  1 
ATOM   1066 C  CG  . GLU A 1 135 ? 166.601 129.762 105.690 1.00 133.08 ? 135 GLU A CG  1 
ATOM   1067 C  CD  . GLU A 1 135 ? 166.304 128.772 106.809 1.00 135.39 ? 135 GLU A CD  1 
ATOM   1068 O  OE1 . GLU A 1 135 ? 167.087 127.811 106.965 1.00 134.48 ? 135 GLU A OE1 1 
ATOM   1069 O  OE2 . GLU A 1 135 ? 165.278 128.920 107.507 1.00 135.15 ? 135 GLU A OE2 1 
ATOM   1070 N  N   . ASP A 1 136 ? 166.955 133.922 107.764 1.00 123.88 ? 136 ASP A N   1 
ATOM   1071 C  CA  . ASP A 1 136 ? 167.613 134.830 108.696 1.00 121.22 ? 136 ASP A CA  1 
ATOM   1072 C  C   . ASP A 1 136 ? 166.656 135.436 109.714 1.00 121.69 ? 136 ASP A C   1 
ATOM   1073 O  O   . ASP A 1 136 ? 167.112 136.110 110.643 1.00 121.11 ? 136 ASP A O   1 
ATOM   1074 C  CB  . ASP A 1 136 ? 168.323 135.948 107.931 1.00 120.19 ? 136 ASP A CB  1 
ATOM   1075 C  CG  . ASP A 1 136 ? 167.427 136.617 106.911 1.00 124.90 ? 136 ASP A CG  1 
ATOM   1076 O  OD1 . ASP A 1 136 ? 166.223 136.288 106.862 1.00 129.88 ? 136 ASP A OD1 1 
ATOM   1077 O  OD2 . ASP A 1 136 ? 167.923 137.479 106.156 1.00 124.30 ? 136 ASP A OD2 1 
ATOM   1078 N  N   . GLY A 1 137 ? 165.351 135.220 109.564 1.00 109.75 ? 137 GLY A N   1 
ATOM   1079 C  CA  . GLY A 1 137 ? 164.389 135.779 110.491 1.00 105.51 ? 137 GLY A CA  1 
ATOM   1080 C  C   . GLY A 1 137 ? 163.842 137.132 110.108 1.00 104.56 ? 137 GLY A C   1 
ATOM   1081 O  O   . GLY A 1 137 ? 163.274 137.819 110.962 1.00 106.57 ? 137 GLY A O   1 
ATOM   1082 N  N   . SER A 1 138 ? 163.994 137.540 108.855 1.00 96.29  ? 138 SER A N   1 
ATOM   1083 C  CA  . SER A 1 138 ? 163.523 138.832 108.388 1.00 94.97  ? 138 SER A CA  1 
ATOM   1084 C  C   . SER A 1 138 ? 162.298 138.676 107.492 1.00 101.35 ? 138 SER A C   1 
ATOM   1085 O  O   . SER A 1 138 ? 162.015 137.601 106.960 1.00 104.85 ? 138 SER A O   1 
ATOM   1086 C  CB  . SER A 1 138 ? 164.628 139.572 107.632 1.00 99.15  ? 138 SER A CB  1 
ATOM   1087 O  OG  . SER A 1 138 ? 165.016 138.856 106.473 1.00 103.32 ? 138 SER A OG  1 
ATOM   1088 N  N   . VAL A 1 139 ? 161.569 139.779 107.338 1.00 96.07  ? 139 VAL A N   1 
ATOM   1089 C  CA  . VAL A 1 139 ? 160.404 139.857 106.467 1.00 92.30  ? 139 VAL A CA  1 
ATOM   1090 C  C   . VAL A 1 139 ? 160.648 140.966 105.455 1.00 92.02  ? 139 VAL A C   1 
ATOM   1091 O  O   . VAL A 1 139 ? 161.044 142.075 105.830 1.00 98.46  ? 139 VAL A O   1 
ATOM   1092 C  CB  . VAL A 1 139 ? 159.112 140.118 107.263 1.00 89.82  ? 139 VAL A CB  1 
ATOM   1093 C  CG1 . VAL A 1 139 ? 157.945 140.358 106.322 1.00 97.35  ? 139 VAL A CG1 1 
ATOM   1094 C  CG2 . VAL A 1 139 ? 158.816 138.951 108.186 1.00 84.88  ? 139 VAL A CG2 1 
ATOM   1095 N  N   . VAL A 1 140 ? 160.423 140.666 104.181 1.00 89.60  ? 140 VAL A N   1 
ATOM   1096 C  CA  . VAL A 1 140 ? 160.599 141.631 103.103 1.00 97.07  ? 140 VAL A CA  1 
ATOM   1097 C  C   . VAL A 1 140 ? 159.227 142.018 102.574 1.00 101.16 ? 140 VAL A C   1 
ATOM   1098 O  O   . VAL A 1 140 ? 158.467 141.164 102.104 1.00 106.13 ? 140 VAL A O   1 
ATOM   1099 C  CB  . VAL A 1 140 ? 161.484 141.068 101.981 1.00 96.81  ? 140 VAL A CB  1 
ATOM   1100 C  CG1 . VAL A 1 140 ? 161.562 142.050 100.829 1.00 93.61  ? 140 VAL A CG1 1 
ATOM   1101 C  CG2 . VAL A 1 140 ? 162.870 140.751 102.511 1.00 93.14  ? 140 VAL A CG2 1 
ATOM   1102 N  N   . ILE A 1 141 ? 158.907 143.308 102.647 1.00 101.88 ? 141 ILE A N   1 
ATOM   1103 C  CA  . ILE A 1 141 ? 157.653 143.839 102.135 1.00 96.40  ? 141 ILE A CA  1 
ATOM   1104 C  C   . ILE A 1 141 ? 157.966 144.816 101.010 1.00 98.95  ? 141 ILE A C   1 
ATOM   1105 O  O   . ILE A 1 141 ? 159.086 145.321 100.896 1.00 105.98 ? 141 ILE A O   1 
ATOM   1106 C  CB  . ILE A 1 141 ? 156.816 144.521 103.239 1.00 93.33  ? 141 ILE A CB  1 
ATOM   1107 C  CG1 . ILE A 1 141 ? 157.592 145.677 103.865 1.00 98.19  ? 141 ILE A CG1 1 
ATOM   1108 C  CG2 . ILE A 1 141 ? 156.409 143.510 104.299 1.00 93.10  ? 141 ILE A CG2 1 
ATOM   1109 C  CD1 . ILE A 1 141 ? 156.720 146.648 104.619 1.00 101.90 ? 141 ILE A CD1 1 
ATOM   1110 N  N   . SER A 1 142 ? 156.968 145.075 100.177 1.00 103.42 ? 142 SER A N   1 
ATOM   1111 C  CA  . SER A 1 142 ? 157.154 145.893 98.990  1.00 107.19 ? 142 SER A CA  1 
ATOM   1112 C  C   . SER A 1 142 ? 157.016 147.380 99.311  1.00 107.92 ? 142 SER A C   1 
ATOM   1113 O  O   . SER A 1 142 ? 156.490 147.781 100.354 1.00 110.46 ? 142 SER A O   1 
ATOM   1114 C  CB  . SER A 1 142 ? 156.152 145.498 97.905  1.00 105.75 ? 142 SER A CB  1 
ATOM   1115 O  OG  . SER A 1 142 ? 154.828 145.511 98.404  1.00 109.71 ? 142 SER A OG  1 
ATOM   1116 N  N   . ASP A 1 143 ? 157.506 148.203 98.378  1.00 102.00 ? 143 ASP A N   1 
ATOM   1117 C  CA  . ASP A 1 143 ? 157.380 149.649 98.522  1.00 105.19 ? 143 ASP A CA  1 
ATOM   1118 C  C   . ASP A 1 143 ? 155.924 150.088 98.518  1.00 110.21 ? 143 ASP A C   1 
ATOM   1119 O  O   . ASP A 1 143 ? 155.569 151.061 99.191  1.00 114.03 ? 143 ASP A O   1 
ATOM   1120 C  CB  . ASP A 1 143 ? 158.154 150.356 97.410  1.00 108.95 ? 143 ASP A CB  1 
ATOM   1121 C  CG  . ASP A 1 143 ? 159.456 149.663 97.077  1.00 113.54 ? 143 ASP A CG  1 
ATOM   1122 O  OD1 . ASP A 1 143 ? 160.304 149.521 97.982  1.00 112.94 ? 143 ASP A OD1 1 
ATOM   1123 O  OD2 . ASP A 1 143 ? 159.634 149.262 95.909  1.00 116.63 ? 143 ASP A OD2 1 
ATOM   1124 N  N   . THR A 1 144 ? 155.070 149.389 97.768  1.00 97.02  ? 144 THR A N   1 
ATOM   1125 C  CA  . THR A 1 144 ? 153.643 149.687 97.813  1.00 98.39  ? 144 THR A CA  1 
ATOM   1126 C  C   . THR A 1 144 ? 153.078 149.440 99.206  1.00 98.75  ? 144 THR A C   1 
ATOM   1127 O  O   . THR A 1 144 ? 152.267 150.229 99.705  1.00 103.68 ? 144 THR A O   1 
ATOM   1128 C  CB  . THR A 1 144 ? 152.894 148.850 96.776  1.00 93.86  ? 144 THR A CB  1 
ATOM   1129 O  OG1 . THR A 1 144 ? 153.550 148.963 95.508  1.00 93.98  ? 144 THR A OG1 1 
ATOM   1130 C  CG2 . THR A 1 144 ? 151.460 149.332 96.640  1.00 96.14  ? 144 THR A CG2 1 
ATOM   1131 N  N   . ARG A 1 145 ? 153.498 148.351 99.851  1.00 76.46  ? 145 ARG A N   1 
ATOM   1132 C  CA  . ARG A 1 145 ? 153.064 148.087 101.218 1.00 76.50  ? 145 ARG A CA  1 
ATOM   1133 C  C   . ARG A 1 145 ? 153.578 149.154 102.178 1.00 86.68  ? 145 ARG A C   1 
ATOM   1134 O  O   . ARG A 1 145 ? 152.852 149.586 103.082 1.00 97.30  ? 145 ARG A O   1 
ATOM   1135 C  CB  . ARG A 1 145 ? 153.527 146.699 101.653 1.00 79.05  ? 145 ARG A CB  1 
ATOM   1136 C  CG  . ARG A 1 145 ? 152.857 146.195 102.912 1.00 81.86  ? 145 ARG A CG  1 
ATOM   1137 C  CD  . ARG A 1 145 ? 152.897 144.685 102.988 1.00 78.52  ? 145 ARG A CD  1 
ATOM   1138 N  NE  . ARG A 1 145 ? 152.353 144.190 104.245 1.00 80.22  ? 145 ARG A NE  1 
ATOM   1139 C  CZ  . ARG A 1 145 ? 152.358 142.916 104.611 1.00 82.33  ? 145 ARG A CZ  1 
ATOM   1140 N  NH1 . ARG A 1 145 ? 152.873 141.977 103.836 1.00 86.85  ? 145 ARG A NH1 1 
ATOM   1141 N  NH2 . ARG A 1 145 ? 151.835 142.576 105.784 1.00 80.99  ? 145 ARG A NH2 1 
ATOM   1142 N  N   . VAL A 1 146 ? 154.828 149.587 101.998 1.00 80.38  ? 146 VAL A N   1 
ATOM   1143 C  CA  . VAL A 1 146 ? 155.374 150.647 102.842 1.00 82.30  ? 146 VAL A CA  1 
ATOM   1144 C  C   . VAL A 1 146 ? 154.554 151.923 102.687 1.00 87.14  ? 146 VAL A C   1 
ATOM   1145 O  O   . VAL A 1 146 ? 154.203 152.584 103.676 1.00 91.85  ? 146 VAL A O   1 
ATOM   1146 C  CB  . VAL A 1 146 ? 156.858 150.887 102.507 1.00 83.44  ? 146 VAL A CB  1 
ATOM   1147 C  CG1 . VAL A 1 146 ? 157.378 152.114 103.234 1.00 88.80  ? 146 VAL A CG1 1 
ATOM   1148 C  CG2 . VAL A 1 146 ? 157.686 149.667 102.856 1.00 82.86  ? 146 VAL A CG2 1 
ATOM   1149 N  N   . LYS A 1 147 ? 154.227 152.282 101.445 1.00 78.35  ? 147 LYS A N   1 
ATOM   1150 C  CA  . LYS A 1 147 ? 153.428 153.477 101.194 1.00 79.00  ? 147 LYS A CA  1 
ATOM   1151 C  C   . LYS A 1 147 ? 152.023 153.349 101.768 1.00 86.41  ? 147 LYS A C   1 
ATOM   1152 O  O   . LYS A 1 147 ? 151.476 154.330 102.279 1.00 91.52  ? 147 LYS A O   1 
ATOM   1153 C  CB  . LYS A 1 147 ? 153.373 153.760 99.694  1.00 78.63  ? 147 LYS A CB  1 
ATOM   1154 C  CG  . LYS A 1 147 ? 154.606 154.468 99.163  1.00 83.94  ? 147 LYS A CG  1 
ATOM   1155 C  CD  . LYS A 1 147 ? 154.331 155.144 97.833  1.00 90.34  ? 147 LYS A CD  1 
ATOM   1156 C  CE  . LYS A 1 147 ? 154.046 154.124 96.744  1.00 91.02  ? 147 LYS A CE  1 
ATOM   1157 N  NZ  . LYS A 1 147 ? 155.297 153.500 96.232  1.00 91.05  ? 147 LYS A NZ  1 
ATOM   1158 N  N   . ALA A 1 148 ? 151.423 152.159 101.690 1.00 86.82  ? 148 ALA A N   1 
ATOM   1159 C  CA  . ALA A 1 148 ? 150.105 151.956 102.283 1.00 85.73  ? 148 ALA A CA  1 
ATOM   1160 C  C   . ALA A 1 148 ? 150.146 152.137 103.796 1.00 86.22  ? 148 ALA A C   1 
ATOM   1161 O  O   . ALA A 1 148 ? 149.248 152.762 104.383 1.00 92.17  ? 148 ALA A O   1 
ATOM   1162 C  CB  . ALA A 1 148 ? 149.581 150.566 101.924 1.00 83.47  ? 148 ALA A CB  1 
ATOM   1163 N  N   . ILE A 1 149 ? 151.178 151.598 104.446 1.00 79.91  ? 149 ILE A N   1 
ATOM   1164 C  CA  . ILE A 1 149 ? 151.324 151.777 105.887 1.00 81.72  ? 149 ILE A CA  1 
ATOM   1165 C  C   . ILE A 1 149 ? 151.471 153.255 106.228 1.00 86.55  ? 149 ILE A C   1 
ATOM   1166 O  O   . ILE A 1 149 ? 150.838 153.761 107.165 1.00 92.19  ? 149 ILE A O   1 
ATOM   1167 C  CB  . ILE A 1 149 ? 152.516 150.953 106.408 1.00 84.90  ? 149 ILE A CB  1 
ATOM   1168 C  CG1 . ILE A 1 149 ? 152.243 149.460 106.245 1.00 81.25  ? 149 ILE A CG1 1 
ATOM   1169 C  CG2 . ILE A 1 149 ? 152.804 151.288 107.861 1.00 89.43  ? 149 ILE A CG2 1 
ATOM   1170 C  CD1 . ILE A 1 149 ? 153.485 148.607 106.317 1.00 81.80  ? 149 ILE A CD1 1 
ATOM   1171 N  N   . GLU A 1 150 ? 152.307 153.969 105.469 1.00 91.34  ? 150 GLU A N   1 
ATOM   1172 C  CA  . GLU A 1 150 ? 152.491 155.395 105.717 1.00 92.34  ? 150 GLU A CA  1 
ATOM   1173 C  C   . GLU A 1 150 ? 151.193 156.164 105.502 1.00 96.64  ? 150 GLU A C   1 
ATOM   1174 O  O   . GLU A 1 150 ? 150.923 157.148 106.200 1.00 105.11 ? 150 GLU A O   1 
ATOM   1175 C  CB  . GLU A 1 150 ? 153.596 155.950 104.823 1.00 94.39  ? 150 GLU A CB  1 
ATOM   1176 C  CG  . GLU A 1 150 ? 154.967 155.363 105.101 1.00 99.52  ? 150 GLU A CG  1 
ATOM   1177 C  CD  . GLU A 1 150 ? 156.021 155.859 104.132 1.00 108.18 ? 150 GLU A CD  1 
ATOM   1178 O  OE1 . GLU A 1 150 ? 155.672 156.156 102.971 1.00 108.88 ? 150 GLU A OE1 1 
ATOM   1179 O  OE2 . GLU A 1 150 ? 157.201 155.947 104.531 1.00 109.80 ? 150 GLU A OE2 1 
ATOM   1180 N  N   . SER A 1 151 ? 150.381 155.734 104.537 1.00 82.98  ? 151 SER A N   1 
ATOM   1181 C  CA  . SER A 1 151 ? 149.124 156.419 104.265 1.00 80.93  ? 151 SER A CA  1 
ATOM   1182 C  C   . SER A 1 151 ? 148.112 156.197 105.382 1.00 81.67  ? 151 SER A C   1 
ATOM   1183 O  O   . SER A 1 151 ? 147.344 157.105 105.719 1.00 85.15  ? 151 SER A O   1 
ATOM   1184 C  CB  . SER A 1 151 ? 148.556 155.958 102.924 1.00 82.40  ? 151 SER A CB  1 
ATOM   1185 O  OG  . SER A 1 151 ? 147.586 154.945 103.103 1.00 88.67  ? 151 SER A OG  1 
ATOM   1186 N  N   . ILE A 1 152 ? 148.080 154.992 105.963 1.00 78.99  ? 152 ILE A N   1 
ATOM   1187 C  CA  . ILE A 1 152 ? 147.095 154.714 107.011 1.00 77.53  ? 152 ILE A CA  1 
ATOM   1188 C  C   . ILE A 1 152 ? 147.563 155.108 108.407 1.00 80.28  ? 152 ILE A C   1 
ATOM   1189 O  O   . ILE A 1 152 ? 146.742 155.111 109.339 1.00 83.57  ? 152 ILE A O   1 
ATOM   1190 C  CB  . ILE A 1 152 ? 146.675 153.232 107.038 1.00 75.34  ? 152 ILE A CB  1 
ATOM   1191 C  CG1 . ILE A 1 152 ? 147.762 152.368 107.684 1.00 74.43  ? 152 ILE A CG1 1 
ATOM   1192 C  CG2 . ILE A 1 152 ? 146.323 152.744 105.641 1.00 86.35  ? 152 ILE A CG2 1 
ATOM   1193 C  CD1 . ILE A 1 152 ? 147.299 150.975 108.030 1.00 76.32  ? 152 ILE A CD1 1 
ATOM   1194 N  N   . LEU A 1 153 ? 148.841 155.433 108.590 1.00 80.94  ? 153 LEU A N   1 
ATOM   1195 C  CA  . LEU A 1 153 ? 149.333 155.840 109.907 1.00 75.92  ? 153 LEU A CA  1 
ATOM   1196 C  C   . LEU A 1 153 ? 148.649 157.076 110.508 1.00 83.35  ? 153 LEU A C   1 
ATOM   1197 O  O   . LEU A 1 153 ? 148.343 157.068 111.709 1.00 90.10  ? 153 LEU A O   1 
ATOM   1198 C  CB  . LEU A 1 153 ? 150.845 156.075 109.846 1.00 78.01  ? 153 LEU A CB  1 
ATOM   1199 C  CG  . LEU A 1 153 ? 151.709 154.843 110.109 1.00 81.10  ? 153 LEU A CG  1 
ATOM   1200 C  CD1 . LEU A 1 153 ? 153.174 155.150 109.854 1.00 87.08  ? 153 LEU A CD1 1 
ATOM   1201 C  CD2 . LEU A 1 153 ? 151.501 154.337 111.522 1.00 75.25  ? 153 LEU A CD2 1 
ATOM   1202 N  N   . PRO A 1 154 ? 148.420 158.157 109.745 1.00 81.62  ? 154 PRO A N   1 
ATOM   1203 C  CA  . PRO A 1 154 ? 147.843 159.366 110.366 1.00 78.75  ? 154 PRO A CA  1 
ATOM   1204 C  C   . PRO A 1 154 ? 146.492 159.151 111.026 1.00 83.18  ? 154 PRO A C   1 
ATOM   1205 O  O   . PRO A 1 154 ? 146.205 159.793 112.045 1.00 82.22  ? 154 PRO A O   1 
ATOM   1206 C  CB  . PRO A 1 154 ? 147.740 160.345 109.191 1.00 75.58  ? 154 PRO A CB  1 
ATOM   1207 C  CG  . PRO A 1 154 ? 148.779 159.904 108.251 1.00 77.84  ? 154 PRO A CG  1 
ATOM   1208 C  CD  . PRO A 1 154 ? 148.782 158.413 108.339 1.00 82.16  ? 154 PRO A CD  1 
ATOM   1209 N  N   . TYR A 1 155 ? 145.646 158.278 110.474 1.00 87.45  ? 155 TYR A N   1 
ATOM   1210 C  CA  . TYR A 1 155 ? 144.344 158.029 111.083 1.00 86.67  ? 155 TYR A CA  1 
ATOM   1211 C  C   . TYR A 1 155 ? 144.500 157.458 112.486 1.00 84.55  ? 155 TYR A C   1 
ATOM   1212 O  O   . TYR A 1 155 ? 143.844 157.911 113.431 1.00 96.17  ? 155 TYR A O   1 
ATOM   1213 C  CB  . TYR A 1 155 ? 143.526 157.083 110.204 1.00 81.81  ? 155 TYR A CB  1 
ATOM   1214 C  CG  . TYR A 1 155 ? 142.325 156.486 110.901 1.00 81.98  ? 155 TYR A CG  1 
ATOM   1215 C  CD1 . TYR A 1 155 ? 141.154 157.214 111.049 1.00 84.64  ? 155 TYR A CD1 1 
ATOM   1216 C  CD2 . TYR A 1 155 ? 142.363 155.198 111.412 1.00 84.86  ? 155 TYR A CD2 1 
ATOM   1217 C  CE1 . TYR A 1 155 ? 140.056 156.677 111.686 1.00 87.96  ? 155 TYR A CE1 1 
ATOM   1218 C  CE2 . TYR A 1 155 ? 141.271 154.652 112.051 1.00 84.21  ? 155 TYR A CE2 1 
ATOM   1219 C  CZ  . TYR A 1 155 ? 140.119 155.396 112.184 1.00 89.18  ? 155 TYR A CZ  1 
ATOM   1220 O  OH  . TYR A 1 155 ? 139.026 154.857 112.818 1.00 88.13  ? 155 TYR A OH  1 
ATOM   1221 N  N   . TYR A 1 156 ? 145.373 156.462 112.641 1.00 70.97  ? 156 TYR A N   1 
ATOM   1222 C  CA  . TYR A 1 156 ? 145.584 155.869 113.954 1.00 71.62  ? 156 TYR A CA  1 
ATOM   1223 C  C   . TYR A 1 156 ? 146.284 156.833 114.898 1.00 78.91  ? 156 TYR A C   1 
ATOM   1224 O  O   . TYR A 1 156 ? 145.995 156.838 116.102 1.00 81.92  ? 156 TYR A O   1 
ATOM   1225 C  CB  . TYR A 1 156 ? 146.375 154.569 113.816 1.00 76.39  ? 156 TYR A CB  1 
ATOM   1226 C  CG  . TYR A 1 156 ? 145.564 153.461 113.195 1.00 78.99  ? 156 TYR A CG  1 
ATOM   1227 C  CD1 . TYR A 1 156 ? 144.618 152.771 113.939 1.00 80.58  ? 156 TYR A CD1 1 
ATOM   1228 C  CD2 . TYR A 1 156 ? 145.726 153.117 111.862 1.00 81.00  ? 156 TYR A CD2 1 
ATOM   1229 C  CE1 . TYR A 1 156 ? 143.868 151.762 113.377 1.00 81.13  ? 156 TYR A CE1 1 
ATOM   1230 C  CE2 . TYR A 1 156 ? 144.980 152.110 111.290 1.00 79.07  ? 156 TYR A CE2 1 
ATOM   1231 C  CZ  . TYR A 1 156 ? 144.052 151.437 112.053 1.00 83.74  ? 156 TYR A CZ  1 
ATOM   1232 O  OH  . TYR A 1 156 ? 143.304 150.432 111.490 1.00 91.43  ? 156 TYR A OH  1 
ATOM   1233 N  N   . HIS A 1 157 ? 147.198 157.658 114.380 1.00 88.80  ? 157 HIS A N   1 
ATOM   1234 C  CA  . HIS A 1 157 ? 147.803 158.683 115.222 1.00 88.21  ? 157 HIS A CA  1 
ATOM   1235 C  C   . HIS A 1 157 ? 146.767 159.655 115.765 1.00 90.45  ? 157 HIS A C   1 
ATOM   1236 O  O   . HIS A 1 157 ? 146.798 159.974 116.959 1.00 89.17  ? 157 HIS A O   1 
ATOM   1237 C  CB  . HIS A 1 157 ? 148.877 159.447 114.447 1.00 85.52  ? 157 HIS A CB  1 
ATOM   1238 C  CG  . HIS A 1 157 ? 150.255 158.892 114.624 1.00 84.04  ? 157 HIS A CG  1 
ATOM   1239 N  ND1 . HIS A 1 157 ? 150.946 158.982 115.814 1.00 90.03  ? 157 HIS A ND1 1 
ATOM   1240 C  CD2 . HIS A 1 157 ? 151.070 158.240 113.764 1.00 86.47  ? 157 HIS A CD2 1 
ATOM   1241 C  CE1 . HIS A 1 157 ? 152.128 158.408 115.677 1.00 93.58  ? 157 HIS A CE1 1 
ATOM   1242 N  NE2 . HIS A 1 157 ? 152.228 157.949 114.443 1.00 91.39  ? 157 HIS A NE2 1 
ATOM   1243 N  N   . GLY A 1 158 ? 145.842 160.118 114.921 1.00 86.11  ? 158 GLY A N   1 
ATOM   1244 C  CA  . GLY A 1 158 ? 144.776 160.980 115.399 1.00 85.63  ? 158 GLY A CA  1 
ATOM   1245 C  C   . GLY A 1 158 ? 143.805 160.290 116.330 1.00 84.68  ? 158 GLY A C   1 
ATOM   1246 O  O   . GLY A 1 158 ? 143.278 160.918 117.252 1.00 91.85  ? 158 GLY A O   1 
ATOM   1247 N  N   . VAL A 1 159 ? 143.546 159.002 116.107 1.00 79.14  ? 159 VAL A N   1 
ATOM   1248 C  CA  . VAL A 1 159 ? 142.632 158.269 116.976 1.00 76.68  ? 159 VAL A CA  1 
ATOM   1249 C  C   . VAL A 1 159 ? 143.224 158.083 118.368 1.00 78.61  ? 159 VAL A C   1 
ATOM   1250 O  O   . VAL A 1 159 ? 142.529 158.281 119.371 1.00 79.44  ? 159 VAL A O   1 
ATOM   1251 C  CB  . VAL A 1 159 ? 142.257 156.921 116.339 1.00 76.31  ? 159 VAL A CB  1 
ATOM   1252 C  CG1 . VAL A 1 159 ? 141.840 155.917 117.402 1.00 61.64  ? 159 VAL A CG1 1 
ATOM   1253 C  CG2 . VAL A 1 159 ? 141.148 157.107 115.320 1.00 84.47  ? 159 VAL A CG2 1 
ATOM   1254 N  N   . TYR A 1 160 ? 144.500 157.713 118.465 1.00 80.25  ? 160 TYR A N   1 
ATOM   1255 C  CA  . TYR A 1 160 ? 145.112 157.474 119.765 1.00 76.15  ? 160 TYR A CA  1 
ATOM   1256 C  C   . TYR A 1 160 ? 145.692 158.726 120.409 1.00 80.21  ? 160 TYR A C   1 
ATOM   1257 O  O   . TYR A 1 160 ? 146.061 158.680 121.587 1.00 80.43  ? 160 TYR A O   1 
ATOM   1258 C  CB  . TYR A 1 160 ? 146.211 156.411 119.648 1.00 74.62  ? 160 TYR A CB  1 
ATOM   1259 C  CG  . TYR A 1 160 ? 145.737 155.024 120.012 1.00 71.64  ? 160 TYR A CG  1 
ATOM   1260 C  CD1 . TYR A 1 160 ? 145.184 154.186 119.053 1.00 74.10  ? 160 TYR A CD1 1 
ATOM   1261 C  CD2 . TYR A 1 160 ? 145.832 154.557 121.313 1.00 71.96  ? 160 TYR A CD2 1 
ATOM   1262 C  CE1 . TYR A 1 160 ? 144.745 152.919 119.381 1.00 75.07  ? 160 TYR A CE1 1 
ATOM   1263 C  CE2 . TYR A 1 160 ? 145.396 153.292 121.650 1.00 73.94  ? 160 TYR A CE2 1 
ATOM   1264 C  CZ  . TYR A 1 160 ? 144.854 152.478 120.681 1.00 75.99  ? 160 TYR A CZ  1 
ATOM   1265 O  OH  . TYR A 1 160 ? 144.420 151.218 121.013 1.00 82.79  ? 160 TYR A OH  1 
ATOM   1266 N  N   . GLY A 1 161 ? 145.590 159.866 119.743 1.00 87.72  ? 161 GLY A N   1 
ATOM   1267 C  CA  . GLY A 1 161 ? 145.991 161.161 120.304 1.00 84.65  ? 161 GLY A CA  1 
ATOM   1268 C  C   . GLY A 1 161 ? 144.818 162.115 120.532 1.00 86.65  ? 161 GLY A C   1 
ATOM   1269 O  O   . GLY A 1 161 ? 143.817 161.669 121.033 1.00 96.31  ? 161 GLY A O   1 
ATOM   1270 N  N   . ASP A 1 162 ? 144.953 163.390 120.177 1.00 105.91 ? 162 ASP A N   1 
ATOM   1271 C  CA  . ASP A 1 162 ? 143.952 164.451 120.466 1.00 102.78 ? 162 ASP A CA  1 
ATOM   1272 C  C   . ASP A 1 162 ? 143.636 165.387 119.298 1.00 108.39 ? 162 ASP A C   1 
ATOM   1273 O  O   . ASP A 1 162 ? 143.180 166.480 119.578 1.00 112.99 ? 162 ASP A O   1 
ATOM   1274 C  CB  . ASP A 1 162 ? 144.437 165.358 121.592 1.00 106.01 ? 162 ASP A CB  1 
ATOM   1275 C  CG  . ASP A 1 162 ? 145.771 166.039 121.351 1.00 113.72 ? 162 ASP A CG  1 
ATOM   1276 O  OD1 . ASP A 1 162 ? 146.268 165.983 120.229 1.00 118.33 ? 162 ASP A OD1 1 
ATOM   1277 O  OD2 . ASP A 1 162 ? 146.290 166.625 122.300 1.00 113.01 ? 162 ASP A OD2 1 
ATOM   1278 N  N   . ASP A 1 163 ? 143.807 164.983 118.052 1.00 109.37 ? 163 ASP A N   1 
ATOM   1279 C  CA  . ASP A 1 163 ? 143.412 165.758 116.847 1.00 109.27 ? 163 ASP A CA  1 
ATOM   1280 C  C   . ASP A 1 163 ? 141.917 166.159 116.813 1.00 110.51 ? 163 ASP A C   1 
ATOM   1281 O  O   . ASP A 1 163 ? 141.135 165.225 116.892 1.00 116.27 ? 163 ASP A O   1 
ATOM   1282 C  CB  . ASP A 1 163 ? 143.796 164.892 115.639 1.00 108.29 ? 163 ASP A CB  1 
ATOM   1283 C  CG  . ASP A 1 163 ? 143.717 165.573 114.295 1.00 114.37 ? 163 ASP A CG  1 
ATOM   1284 O  OD1 . ASP A 1 163 ? 143.756 166.805 114.257 1.00 119.87 ? 163 ASP A OD1 1 
ATOM   1285 O  OD2 . ASP A 1 163 ? 143.635 164.853 113.310 1.00 114.30 ? 163 ASP A OD2 1 
ATOM   1286 N  N   . PRO A 1 164 ? 141.498 167.462 116.653 1.00 104.04 ? 164 PRO A N   1 
ATOM   1287 C  CA  . PRO A 1 164 ? 140.107 167.927 116.528 1.00 109.23 ? 164 PRO A CA  1 
ATOM   1288 C  C   . PRO A 1 164 ? 139.354 167.294 115.373 1.00 111.12 ? 164 PRO A C   1 
ATOM   1289 O  O   . PRO A 1 164 ? 138.128 167.148 115.449 1.00 111.09 ? 164 PRO A O   1 
ATOM   1290 C  CB  . PRO A 1 164 ? 140.262 169.443 116.340 1.00 111.35 ? 164 PRO A CB  1 
ATOM   1291 C  CG  . PRO A 1 164 ? 141.676 169.642 115.904 1.00 106.60 ? 164 PRO A CG  1 
ATOM   1292 C  CD  . PRO A 1 164 ? 142.461 168.572 116.582 1.00 103.42 ? 164 PRO A CD  1 
ATOM   1293 N  N   . ALA A 1 165 ? 140.051 166.908 114.303 1.00 102.15 ? 165 ALA A N   1 
ATOM   1294 C  CA  . ALA A 1 165 ? 139.386 166.290 113.164 1.00 100.88 ? 165 ALA A CA  1 
ATOM   1295 C  C   . ALA A 1 165 ? 138.865 164.894 113.476 1.00 96.26  ? 165 ALA A C   1 
ATOM   1296 O  O   . ALA A 1 165 ? 138.060 164.362 112.704 1.00 99.89  ? 165 ALA A O   1 
ATOM   1297 C  CB  . ALA A 1 165 ? 140.337 166.232 111.969 1.00 101.67 ? 165 ALA A CB  1 
ATOM   1298 N  N   . LEU A 1 166 ? 139.300 164.288 114.579 1.00 89.78  ? 166 LEU A N   1 
ATOM   1299 C  CA  . LEU A 1 166 ? 138.910 162.930 114.935 1.00 92.33  ? 166 LEU A CA  1 
ATOM   1300 C  C   . LEU A 1 166 ? 138.234 162.869 116.301 1.00 90.55  ? 166 LEU A C   1 
ATOM   1301 O  O   . LEU A 1 166 ? 138.205 161.816 116.941 1.00 84.18  ? 166 LEU A O   1 
ATOM   1302 C  CB  . LEU A 1 166 ? 140.127 162.009 114.891 1.00 91.03  ? 166 LEU A CB  1 
ATOM   1303 C  CG  . LEU A 1 166 ? 140.372 161.325 113.544 1.00 94.46  ? 166 LEU A CG  1 
ATOM   1304 C  CD1 . LEU A 1 166 ? 141.849 161.101 113.314 1.00 89.43  ? 166 LEU A CD1 1 
ATOM   1305 C  CD2 . LEU A 1 166 ? 139.619 160.013 113.457 1.00 96.39  ? 166 LEU A CD2 1 
ATOM   1306 N  N   . GLN A 1 167 ? 137.682 163.997 116.757 1.00 99.72  ? 167 GLN A N   1 
ATOM   1307 C  CA  . GLN A 1 167 ? 137.018 164.033 118.056 1.00 96.29  ? 167 GLN A CA  1 
ATOM   1308 C  C   . GLN A 1 167 ? 135.784 163.141 118.081 1.00 97.17  ? 167 GLN A C   1 
ATOM   1309 O  O   . GLN A 1 167 ? 135.564 162.400 119.045 1.00 99.09  ? 167 GLN A O   1 
ATOM   1310 C  CB  . GLN A 1 167 ? 136.639 165.472 118.406 1.00 100.43 ? 167 GLN A CB  1 
ATOM   1311 C  CG  . GLN A 1 167 ? 135.903 165.620 119.725 1.00 101.85 ? 167 GLN A CG  1 
ATOM   1312 C  CD  . GLN A 1 167 ? 136.790 165.361 120.920 1.00 104.83 ? 167 GLN A CD  1 
ATOM   1313 O  OE1 . GLN A 1 167 ? 137.988 165.638 120.890 1.00 102.26 ? 167 GLN A OE1 1 
ATOM   1314 N  NE2 . GLN A 1 167 ? 136.208 164.824 121.983 1.00 106.81 ? 167 GLN A NE2 1 
ATOM   1315 N  N   . THR A 1 168 ? 134.962 163.204 117.031 1.00 94.01  ? 168 THR A N   1 
ATOM   1316 C  CA  . THR A 1 168 ? 133.739 162.407 117.001 1.00 95.62  ? 168 THR A CA  1 
ATOM   1317 C  C   . THR A 1 168 ? 134.051 160.917 116.957 1.00 96.10  ? 168 THR A C   1 
ATOM   1318 O  O   . THR A 1 168 ? 133.374 160.114 117.609 1.00 98.35  ? 168 THR A O   1 
ATOM   1319 C  CB  . THR A 1 168 ? 132.879 162.815 115.806 1.00 94.97  ? 168 THR A CB  1 
ATOM   1320 O  OG1 . THR A 1 168 ? 132.637 164.227 115.852 1.00 99.82  ? 168 THR A OG1 1 
ATOM   1321 C  CG2 . THR A 1 168 ? 131.550 162.089 115.833 1.00 94.69  ? 168 THR A CG2 1 
ATOM   1322 N  N   . THR A 1 169 ? 135.073 160.528 116.192 1.00 89.96  ? 169 THR A N   1 
ATOM   1323 C  CA  . THR A 1 169 ? 135.462 159.124 116.131 1.00 87.40  ? 169 THR A CA  1 
ATOM   1324 C  C   . THR A 1 169 ? 135.926 158.621 117.491 1.00 84.58  ? 169 THR A C   1 
ATOM   1325 O  O   . THR A 1 169 ? 135.581 157.506 117.901 1.00 84.30  ? 169 THR A O   1 
ATOM   1326 C  CB  . THR A 1 169 ? 136.561 158.930 115.088 1.00 88.88  ? 169 THR A CB  1 
ATOM   1327 O  OG1 . THR A 1 169 ? 136.047 159.235 113.787 1.00 94.03  ? 169 THR A OG1 1 
ATOM   1328 C  CG2 . THR A 1 169 ? 137.064 157.500 115.099 1.00 83.64  ? 169 THR A CG2 1 
ATOM   1329 N  N   . ARG A 1 170 ? 136.704 159.433 118.209 1.00 86.04  ? 170 ARG A N   1 
ATOM   1330 C  CA  . ARG A 1 170 ? 137.171 159.040 119.532 1.00 84.15  ? 170 ARG A CA  1 
ATOM   1331 C  C   . ARG A 1 170 ? 136.014 158.860 120.504 1.00 86.48  ? 170 ARG A C   1 
ATOM   1332 O  O   . ARG A 1 170 ? 136.032 157.936 121.324 1.00 94.58  ? 170 ARG A O   1 
ATOM   1333 C  CB  . ARG A 1 170 ? 138.161 160.076 120.062 1.00 84.28  ? 170 ARG A CB  1 
ATOM   1334 C  CG  . ARG A 1 170 ? 139.609 159.651 119.935 1.00 82.15  ? 170 ARG A CG  1 
ATOM   1335 C  CD  . ARG A 1 170 ? 140.568 160.671 120.530 1.00 83.46  ? 170 ARG A CD  1 
ATOM   1336 N  NE  . ARG A 1 170 ? 140.100 162.044 120.395 1.00 88.75  ? 170 ARG A NE  1 
ATOM   1337 C  CZ  . ARG A 1 170 ? 140.553 162.903 119.495 1.00 87.30  ? 170 ARG A CZ  1 
ATOM   1338 N  NH1 . ARG A 1 170 ? 141.466 162.555 118.605 1.00 88.25  ? 170 ARG A NH1 1 
ATOM   1339 N  NH2 . ARG A 1 170 ? 140.081 164.145 119.489 1.00 87.35  ? 170 ARG A NH2 1 
ATOM   1340 N  N   . GLU A 1 171 ? 135.006 159.730 120.430 1.00 93.78  ? 171 GLU A N   1 
ATOM   1341 C  CA  . GLU A 1 171 ? 133.836 159.612 121.292 1.00 94.67  ? 171 GLU A CA  1 
ATOM   1342 C  C   . GLU A 1 171 ? 133.039 158.348 120.995 1.00 95.95  ? 171 GLU A C   1 
ATOM   1343 O  O   . GLU A 1 171 ? 132.577 157.672 121.920 1.00 101.55 ? 171 GLU A O   1 
ATOM   1344 C  CB  . GLU A 1 171 ? 132.953 160.848 121.134 1.00 99.96  ? 171 GLU A CB  1 
ATOM   1345 C  CG  . GLU A 1 171 ? 133.550 162.107 121.729 1.00 106.14 ? 171 GLU A CG  1 
ATOM   1346 C  CD  . GLU A 1 171 ? 132.679 163.323 121.506 1.00 108.65 ? 171 GLU A CD  1 
ATOM   1347 O  OE1 . GLU A 1 171 ? 131.641 163.194 120.824 1.00 106.17 ? 171 GLU A OE1 1 
ATOM   1348 O  OE2 . GLU A 1 171 ? 133.032 164.411 122.008 1.00 107.73 ? 171 GLU A OE2 1 
ATOM   1349 N  N   . HIS A 1 172 ? 132.867 158.013 119.714 1.00 84.38  ? 172 HIS A N   1 
ATOM   1350 C  CA  . HIS A 1 172 ? 132.150 156.799 119.345 1.00 87.19  ? 172 HIS A CA  1 
ATOM   1351 C  C   . HIS A 1 172 ? 132.894 155.538 119.757 1.00 90.57  ? 172 HIS A C   1 
ATOM   1352 O  O   . HIS A 1 172 ? 132.265 154.488 119.919 1.00 92.10  ? 172 HIS A O   1 
ATOM   1353 C  CB  . HIS A 1 172 ? 131.893 156.775 117.839 1.00 86.74  ? 172 HIS A CB  1 
ATOM   1354 C  CG  . HIS A 1 172 ? 130.904 157.799 117.381 1.00 87.15  ? 172 HIS A CG  1 
ATOM   1355 N  ND1 . HIS A 1 172 ? 130.753 158.146 116.056 1.00 87.20  ? 172 HIS A ND1 1 
ATOM   1356 C  CD2 . HIS A 1 172 ? 130.010 158.548 118.068 1.00 89.80  ? 172 HIS A CD2 1 
ATOM   1357 C  CE1 . HIS A 1 172 ? 129.812 159.066 115.947 1.00 90.05  ? 172 HIS A CE1 1 
ATOM   1358 N  NE2 . HIS A 1 172 ? 129.346 159.329 117.154 1.00 92.04  ? 172 HIS A NE2 1 
ATOM   1359 N  N   . PHE A 1 173 ? 134.212 155.615 119.929 1.00 81.54  ? 173 PHE A N   1 
ATOM   1360 C  CA  . PHE A 1 173 ? 135.010 154.484 120.380 1.00 80.00  ? 173 PHE A CA  1 
ATOM   1361 C  C   . PHE A 1 173 ? 135.116 154.403 121.895 1.00 85.94  ? 173 PHE A C   1 
ATOM   1362 O  O   . PHE A 1 173 ? 135.759 153.479 122.400 1.00 93.76  ? 173 PHE A O   1 
ATOM   1363 C  CB  . PHE A 1 173 ? 136.421 154.552 119.784 1.00 76.93  ? 173 PHE A CB  1 
ATOM   1364 C  CG  . PHE A 1 173 ? 136.479 154.247 118.316 1.00 77.89  ? 173 PHE A CG  1 
ATOM   1365 C  CD1 . PHE A 1 173 ? 135.375 153.747 117.651 1.00 82.17  ? 173 PHE A CD1 1 
ATOM   1366 C  CD2 . PHE A 1 173 ? 137.643 154.464 117.600 1.00 82.21  ? 173 PHE A CD2 1 
ATOM   1367 C  CE1 . PHE A 1 173 ? 135.428 153.470 116.302 1.00 85.36  ? 173 PHE A CE1 1 
ATOM   1368 C  CE2 . PHE A 1 173 ? 137.704 154.187 116.251 1.00 85.38  ? 173 PHE A CE2 1 
ATOM   1369 C  CZ  . PHE A 1 173 ? 136.594 153.691 115.600 1.00 84.95  ? 173 PHE A CZ  1 
ATOM   1370 N  N   . ALA A 1 174 ? 134.499 155.338 122.620 1.00 82.28  ? 174 ALA A N   1 
ATOM   1371 C  CA  . ALA A 1 174 ? 134.607 155.422 124.077 1.00 78.92  ? 174 ALA A CA  1 
ATOM   1372 C  C   . ALA A 1 174 ? 136.067 155.517 124.514 1.00 84.04  ? 174 ALA A C   1 
ATOM   1373 O  O   . ALA A 1 174 ? 136.496 154.863 125.466 1.00 91.44  ? 174 ALA A O   1 
ATOM   1374 C  CB  . ALA A 1 174 ? 133.906 154.246 124.760 1.00 81.07  ? 174 ALA A CB  1 
ATOM   1375 N  N   . MET A 1 175 ? 136.795 156.362 123.811 1.00 76.44  ? 175 MET A N   1 
ATOM   1376 C  CA  . MET A 1 175 ? 138.232 156.536 124.082 1.00 75.17  ? 175 MET A CA  1 
ATOM   1377 C  C   . MET A 1 175 ? 138.448 157.957 124.586 1.00 80.16  ? 175 MET A C   1 
ATOM   1378 O  O   . MET A 1 175 ? 137.773 158.840 124.104 1.00 87.63  ? 175 MET A O   1 
ATOM   1379 C  CB  . MET A 1 175 ? 139.007 156.293 122.797 1.00 75.78  ? 175 MET A CB  1 
ATOM   1380 C  CG  . MET A 1 175 ? 139.298 154.842 122.540 1.00 77.34  ? 175 MET A CG  1 
ATOM   1381 S  SD  . MET A 1 175 ? 140.037 154.579 120.924 1.00 82.36  ? 175 MET A SD  1 
ATOM   1382 C  CE  . MET A 1 175 ? 141.772 154.808 121.296 1.00 88.58  ? 175 MET A CE  1 
ATOM   1383 N  N   . LYS A 1 176 ? 139.298 158.148 125.575 1.00 87.69  ? 176 LYS A N   1 
ATOM   1384 C  CA  . LYS A 1 176 ? 139.626 159.487 126.119 1.00 87.09  ? 176 LYS A CA  1 
ATOM   1385 C  C   . LYS A 1 176 ? 140.354 160.290 125.049 1.00 91.30  ? 176 LYS A C   1 
ATOM   1386 O  O   . LYS A 1 176 ? 140.774 159.711 124.085 1.00 96.09  ? 176 LYS A O   1 
ATOM   1387 C  CB  . LYS A 1 176 ? 140.464 159.337 127.389 1.00 82.41  ? 176 LYS A CB  1 
ATOM   1388 C  CG  . LYS A 1 176 ? 141.859 158.769 127.198 1.00 84.60  ? 176 LYS A CG  1 
ATOM   1389 C  CD  . LYS A 1 176 ? 142.557 158.501 128.500 1.00 85.83  ? 176 LYS A CD  1 
ATOM   1390 C  CE  . LYS A 1 176 ? 142.859 159.764 129.269 1.00 84.73  ? 176 LYS A CE  1 
ATOM   1391 N  NZ  . LYS A 1 176 ? 143.910 159.540 130.285 1.00 83.49  ? 176 LYS A NZ  1 
ATOM   1392 N  N   . ASN A 1 177 ? 140.548 161.569 125.270 1.00 95.75  ? 177 ASN A N   1 
ATOM   1393 C  CA  . ASN A 1 177 ? 141.132 162.452 124.234 1.00 96.71  ? 177 ASN A CA  1 
ATOM   1394 C  C   . ASN A 1 177 ? 142.626 162.223 124.057 1.00 100.26 ? 177 ASN A C   1 
ATOM   1395 O  O   . ASN A 1 177 ? 143.141 162.596 123.013 1.00 108.03 ? 177 ASN A O   1 
ATOM   1396 C  CB  . ASN A 1 177 ? 140.816 163.928 124.432 1.00 100.42 ? 177 ASN A CB  1 
ATOM   1397 C  CG  . ASN A 1 177 ? 139.791 164.423 123.446 1.00 107.35 ? 177 ASN A CG  1 
ATOM   1398 O  OD1 . ASN A 1 177 ? 139.238 163.637 122.687 1.00 108.51 ? 177 ASN A OD1 1 
ATOM   1399 N  ND2 . ASN A 1 177 ? 139.539 165.719 123.447 1.00 106.88 ? 177 ASN A ND2 1 
ATOM   1400 N  N   . ASN A 1 178 ? 143.293 161.571 124.960 1.00 93.82  ? 178 ASN A N   1 
ATOM   1401 C  CA  . ASN A 1 178 ? 144.695 161.244 124.696 1.00 92.01  ? 178 ASN A CA  1 
ATOM   1402 C  C   . ASN A 1 178 ? 144.991 159.913 125.389 1.00 94.04  ? 178 ASN A C   1 
ATOM   1403 O  O   . ASN A 1 178 ? 145.401 159.882 126.551 1.00 103.26 ? 178 ASN A O   1 
ATOM   1404 C  CB  . ASN A 1 178 ? 145.619 162.349 125.188 1.00 94.25  ? 178 ASN A CB  1 
ATOM   1405 C  CG  . ASN A 1 178 ? 146.560 162.843 124.117 1.00 94.87  ? 178 ASN A CG  1 
ATOM   1406 O  OD1 . ASN A 1 178 ? 147.091 162.061 123.333 1.00 98.84  ? 178 ASN A OD1 1 
ATOM   1407 N  ND2 . ASN A 1 178 ? 146.781 164.150 124.082 1.00 93.57  ? 178 ASN A ND2 1 
ATOM   1408 N  N   . THR A 1 179 ? 144.795 158.819 124.655 1.00 81.59  ? 179 THR A N   1 
ATOM   1409 C  CA  . THR A 1 179 ? 145.047 157.496 125.218 1.00 85.65  ? 179 THR A CA  1 
ATOM   1410 C  C   . THR A 1 179 ? 146.541 157.227 125.334 1.00 89.13  ? 179 THR A C   1 
ATOM   1411 O  O   . THR A 1 179 ? 147.003 156.647 126.322 1.00 92.07  ? 179 THR A O   1 
ATOM   1412 C  CB  . THR A 1 179 ? 144.367 156.423 124.368 1.00 79.70  ? 179 THR A CB  1 
ATOM   1413 O  OG1 . THR A 1 179 ? 143.018 156.815 124.093 1.00 77.97  ? 179 THR A OG1 1 
ATOM   1414 C  CG2 . THR A 1 179 ? 144.362 155.090 125.094 1.00 81.77  ? 179 THR A CG2 1 
ATOM   1415 N  N   . LEU A 1 180 ? 147.309 157.638 124.327 1.00 89.31  ? 180 LEU A N   1 
ATOM   1416 C  CA  . LEU A 1 180 ? 148.765 157.525 124.335 1.00 86.15  ? 180 LEU A CA  1 
ATOM   1417 C  C   . LEU A 1 180 ? 149.331 158.883 123.946 1.00 89.23  ? 180 LEU A C   1 
ATOM   1418 O  O   . LEU A 1 180 ? 149.509 159.179 122.757 1.00 91.71  ? 180 LEU A O   1 
ATOM   1419 C  CB  . LEU A 1 180 ? 149.240 156.419 123.398 1.00 79.73  ? 180 LEU A CB  1 
ATOM   1420 C  CG  . LEU A 1 180 ? 150.652 155.883 123.626 1.00 89.67  ? 180 LEU A CG  1 
ATOM   1421 C  CD1 . LEU A 1 180 ? 150.860 155.528 125.084 1.00 87.88  ? 180 LEU A CD1 1 
ATOM   1422 C  CD2 . LEU A 1 180 ? 150.887 154.670 122.751 1.00 87.18  ? 180 LEU A CD2 1 
ATOM   1423 N  N   . PRO A 1 181 ? 149.606 159.747 124.927 1.00 88.85  ? 181 PRO A N   1 
ATOM   1424 C  CA  . PRO A 1 181 ? 150.081 161.102 124.599 1.00 94.63  ? 181 PRO A CA  1 
ATOM   1425 C  C   . PRO A 1 181 ? 151.394 161.131 123.837 1.00 97.32  ? 181 PRO A C   1 
ATOM   1426 O  O   . PRO A 1 181 ? 151.615 162.055 123.045 1.00 97.62  ? 181 PRO A O   1 
ATOM   1427 C  CB  . PRO A 1 181 ? 150.220 161.768 125.977 1.00 98.36  ? 181 PRO A CB  1 
ATOM   1428 C  CG  . PRO A 1 181 ? 149.420 160.926 126.909 1.00 92.75  ? 181 PRO A CG  1 
ATOM   1429 C  CD  . PRO A 1 181 ? 149.485 159.536 126.376 1.00 84.77  ? 181 PRO A CD  1 
ATOM   1430 N  N   . SER A 1 182 ? 152.273 160.156 124.047 1.00 100.64 ? 182 SER A N   1 
ATOM   1431 C  CA  . SER A 1 182 ? 153.602 160.198 123.447 1.00 102.73 ? 182 SER A CA  1 
ATOM   1432 C  C   . SER A 1 182 ? 153.548 159.755 121.989 1.00 102.54 ? 182 SER A C   1 
ATOM   1433 O  O   . SER A 1 182 ? 153.032 158.676 121.675 1.00 104.90 ? 182 SER A O   1 
ATOM   1434 C  CB  . SER A 1 182 ? 154.564 159.320 124.243 1.00 102.37 ? 182 SER A CB  1 
ATOM   1435 O  OG  . SER A 1 182 ? 155.864 159.363 123.683 1.00 106.48 ? 182 SER A OG  1 
ATOM   1436 N  N   . GLN A 1 183 ? 154.096 160.588 121.103 1.00 99.78  ? 183 GLN A N   1 
ATOM   1437 C  CA  . GLN A 1 183 ? 154.110 160.267 119.680 1.00 97.77  ? 183 GLN A CA  1 
ATOM   1438 C  C   . GLN A 1 183 ? 155.013 159.073 119.387 1.00 103.64 ? 183 GLN A C   1 
ATOM   1439 O  O   . GLN A 1 183 ? 154.678 158.226 118.551 1.00 105.75 ? 183 GLN A O   1 
ATOM   1440 C  CB  . GLN A 1 183 ? 154.547 161.489 118.877 1.00 98.41  ? 183 GLN A CB  1 
ATOM   1441 C  CG  . GLN A 1 183 ? 153.789 161.678 117.578 1.00 96.95  ? 183 GLN A CG  1 
ATOM   1442 C  CD  . GLN A 1 183 ? 154.636 161.377 116.363 1.00 106.66 ? 183 GLN A CD  1 
ATOM   1443 O  OE1 . GLN A 1 183 ? 155.859 161.293 116.452 1.00 110.05 ? 183 GLN A OE1 1 
ATOM   1444 N  NE2 . GLN A 1 183 ? 153.987 161.210 115.218 1.00 105.95 ? 183 GLN A NE2 1 
ATOM   1445 N  N   . GLU A 1 184 ? 156.162 159.054 120.053 1.00 108.62 ? 184 GLU A N   1 
ATOM   1446 C  CA  . GLU A 1 184 ? 157.147 157.963 119.962 1.00 106.62 ? 184 GLU A CA  1 
ATOM   1447 C  C   . GLU A 1 184 ? 156.557 156.624 120.443 1.00 112.50 ? 184 GLU A C   1 
ATOM   1448 O  O   . GLU A 1 184 ? 156.935 155.609 119.821 1.00 117.04 ? 184 GLU A O   1 
ATOM   1449 C  CB  . GLU A 1 184 ? 158.371 158.543 120.659 1.00 105.36 ? 184 GLU A CB  1 
ATOM   1450 C  CG  . GLU A 1 184 ? 159.035 159.660 119.882 1.00 111.51 ? 184 GLU A CG  1 
ATOM   1451 C  CD  . GLU A 1 184 ? 158.807 161.092 120.342 1.00 114.15 ? 184 GLU A CD  1 
ATOM   1452 O  OE1 . GLU A 1 184 ? 158.606 161.308 121.550 1.00 109.53 ? 184 GLU A OE1 1 
ATOM   1453 O  OE2 . GLU A 1 184 ? 158.842 161.996 119.485 1.00 117.63 ? 184 GLU A OE2 1 
ATOM   1454 N  N   . ALA A 1 185 ? 155.737 156.594 121.493 1.00 98.94  ? 185 ALA A N   1 
ATOM   1455 C  CA  . ALA A 1 185 ? 155.012 155.426 121.971 1.00 93.90  ? 185 ALA A CA  1 
ATOM   1456 C  C   . ALA A 1 185 ? 153.902 155.037 121.007 1.00 96.87  ? 185 ALA A C   1 
ATOM   1457 O  O   . ALA A 1 185 ? 153.669 153.846 120.776 1.00 102.71 ? 185 ALA A O   1 
ATOM   1458 C  CB  . ALA A 1 185 ? 154.445 155.694 123.367 1.00 90.57  ? 185 ALA A CB  1 
ATOM   1459 N  N   . ARG A 1 186 ? 153.213 156.025 120.433 1.00 91.51  ? 186 ARG A N   1 
ATOM   1460 C  CA  . ARG A 1 186 ? 152.193 155.733 119.431 1.00 91.41  ? 186 ARG A CA  1 
ATOM   1461 C  C   . ARG A 1 186 ? 152.804 155.057 118.207 1.00 91.82  ? 186 ARG A C   1 
ATOM   1462 O  O   . ARG A 1 186 ? 152.235 154.104 117.660 1.00 101.17 ? 186 ARG A O   1 
ATOM   1463 C  CB  . ARG A 1 186 ? 151.478 157.024 119.035 1.00 88.68  ? 186 ARG A CB  1 
ATOM   1464 C  CG  . ARG A 1 186 ? 149.971 156.975 119.170 1.00 92.05  ? 186 ARG A CG  1 
ATOM   1465 C  CD  . ARG A 1 186 ? 149.427 158.291 119.686 1.00 90.99  ? 186 ARG A CD  1 
ATOM   1466 N  NE  . ARG A 1 186 ? 149.813 159.412 118.837 1.00 89.83  ? 186 ARG A NE  1 
ATOM   1467 C  CZ  . ARG A 1 186 ? 150.057 160.637 119.280 1.00 91.03  ? 186 ARG A CZ  1 
ATOM   1468 N  NH1 . ARG A 1 186 ? 149.955 160.940 120.563 1.00 93.52  ? 186 ARG A NH1 1 
ATOM   1469 N  NH2 . ARG A 1 186 ? 150.411 161.580 118.417 1.00 91.03  ? 186 ARG A NH2 1 
ATOM   1470 N  N   . GLU A 1 187 ? 153.970 155.538 117.769 1.00 88.71  ? 187 GLU A N   1 
ATOM   1471 C  CA  . GLU A 1 187 ? 154.648 154.936 116.626 1.00 90.27  ? 187 GLU A CA  1 
ATOM   1472 C  C   . GLU A 1 187 ? 155.029 153.488 116.896 1.00 94.20  ? 187 GLU A C   1 
ATOM   1473 O  O   . GLU A 1 187 ? 154.873 152.635 116.017 1.00 100.61 ? 187 GLU A O   1 
ATOM   1474 C  CB  . GLU A 1 187 ? 155.889 155.747 116.263 1.00 88.72  ? 187 GLU A CB  1 
ATOM   1475 C  CG  . GLU A 1 187 ? 155.590 157.069 115.586 1.00 98.06  ? 187 GLU A CG  1 
ATOM   1476 C  CD  . GLU A 1 187 ? 156.792 157.986 115.539 1.00 102.86 ? 187 GLU A CD  1 
ATOM   1477 O  OE1 . GLU A 1 187 ? 157.825 157.648 116.153 1.00 103.77 ? 187 GLU A OE1 1 
ATOM   1478 O  OE2 . GLU A 1 187 ? 156.708 159.047 114.886 1.00 105.05 ? 187 GLU A OE2 1 
ATOM   1479 N  N   . LYS A 1 188 ? 155.538 153.195 118.092 1.00 85.31  ? 188 LYS A N   1 
ATOM   1480 C  CA  . LYS A 1 188 ? 155.835 151.809 118.443 1.00 84.80  ? 188 LYS A CA  1 
ATOM   1481 C  C   . LYS A 1 188 ? 154.576 150.951 118.517 1.00 85.78  ? 188 LYS A C   1 
ATOM   1482 O  O   . LYS A 1 188 ? 154.579 149.800 118.052 1.00 96.15  ? 188 LYS A O   1 
ATOM   1483 C  CB  . LYS A 1 188 ? 156.591 151.756 119.770 1.00 82.62  ? 188 LYS A CB  1 
ATOM   1484 C  CG  . LYS A 1 188 ? 157.897 152.521 119.757 1.00 88.19  ? 188 LYS A CG  1 
ATOM   1485 C  CD  . LYS A 1 188 ? 159.039 151.645 119.285 1.00 88.61  ? 188 LYS A CD  1 
ATOM   1486 C  CE  . LYS A 1 188 ? 160.191 152.478 118.756 1.00 93.15  ? 188 LYS A CE  1 
ATOM   1487 N  NZ  . LYS A 1 188 ? 159.820 153.196 117.507 1.00 88.37  ? 188 LYS A NZ  1 
ATOM   1488 N  N   . LEU A 1 189 ? 153.501 151.486 119.098 1.00 74.27  ? 189 LEU A N   1 
ATOM   1489 C  CA  . LEU A 1 189 ? 152.256 150.736 119.194 1.00 75.22  ? 189 LEU A CA  1 
ATOM   1490 C  C   . LEU A 1 189 ? 151.710 150.392 117.814 1.00 77.00  ? 189 LEU A C   1 
ATOM   1491 O  O   . LEU A 1 189 ? 151.161 149.302 117.616 1.00 88.06  ? 189 LEU A O   1 
ATOM   1492 C  CB  . LEU A 1 189 ? 151.230 151.533 120.000 1.00 73.56  ? 189 LEU A CB  1 
ATOM   1493 C  CG  . LEU A 1 189 ? 149.749 151.238 119.759 1.00 68.87  ? 189 LEU A CG  1 
ATOM   1494 C  CD1 . LEU A 1 189 ? 149.361 149.945 120.441 1.00 77.40  ? 189 LEU A CD1 1 
ATOM   1495 C  CD2 . LEU A 1 189 ? 148.887 152.385 120.257 1.00 75.26  ? 189 LEU A CD2 1 
ATOM   1496 N  N   . PHE A 1 190 ? 151.967 151.210 116.795 1.00 81.79  ? 190 PHE A N   1 
ATOM   1497 C  CA  . PHE A 1 190 ? 151.461 150.991 115.412 1.00 79.02  ? 190 PHE A CA  1 
ATOM   1498 C  C   . PHE A 1 190 ? 152.351 149.940 114.739 1.00 80.31  ? 190 PHE A C   1 
ATOM   1499 O  O   . PHE A 1 190 ? 151.897 149.294 113.824 1.00 87.08  ? 190 PHE A O   1 
ATOM   1500 C  CB  . PHE A 1 190 ? 151.200 152.318 114.675 1.00 79.86  ? 190 PHE A CB  1 
ATOM   1501 C  CG  . PHE A 1 190 ? 150.301 153.274 115.411 1.00 85.78  ? 190 PHE A CG  1 
ATOM   1502 C  CD1 . PHE A 1 190 ? 149.298 152.807 116.246 1.00 84.35  ? 190 PHE A CD1 1 
ATOM   1503 C  CD2 . PHE A 1 190 ? 150.463 154.646 115.292 1.00 84.96  ? 190 PHE A CD2 1 
ATOM   1504 C  CE1 . PHE A 1 190 ? 148.489 153.684 116.946 1.00 81.37  ? 190 PHE A CE1 1 
ATOM   1505 C  CE2 . PHE A 1 190 ? 149.647 155.521 115.994 1.00 86.35  ? 190 PHE A CE2 1 
ATOM   1506 C  CZ  . PHE A 1 190 ? 148.670 155.036 116.823 1.00 87.80  ? 190 PHE A CZ  1 
ATOM   1507 N  N   . ASP A 1 191 ? 153.606 149.877 115.172 1.00 82.17  ? 191 ASP A N   1 
ATOM   1508 C  CA  . ASP A 1 191 ? 154.441 148.762 114.734 1.00 81.43  ? 191 ASP A CA  1 
ATOM   1509 C  C   . ASP A 1 191 ? 153.913 147.441 115.278 1.00 83.88  ? 191 ASP A C   1 
ATOM   1510 O  O   . ASP A 1 191 ? 153.868 146.433 114.563 1.00 89.23  ? 191 ASP A O   1 
ATOM   1511 C  CB  . ASP A 1 191 ? 155.887 148.976 115.185 1.00 81.97  ? 191 ASP A CB  1 
ATOM   1512 C  CG  . ASP A 1 191 ? 156.615 150.002 114.349 1.00 98.23  ? 191 ASP A CG  1 
ATOM   1513 O  OD1 . ASP A 1 191 ? 156.179 150.262 113.211 1.00 103.21 ? 191 ASP A OD1 1 
ATOM   1514 O  OD2 . ASP A 1 191 ? 157.627 150.549 114.832 1.00 100.77 ? 191 ASP A OD2 1 
ATOM   1515 N  N   . PHE A 1 192 ? 153.513 147.435 116.549 1.00 75.46  ? 192 PHE A N   1 
ATOM   1516 C  CA  . PHE A 1 192 ? 152.925 146.232 117.136 1.00 68.68  ? 192 PHE A CA  1 
ATOM   1517 C  C   . PHE A 1 192 ? 151.630 145.845 116.421 1.00 73.61  ? 192 PHE A C   1 
ATOM   1518 O  O   . PHE A 1 192 ? 151.382 144.658 116.150 1.00 80.44  ? 192 PHE A O   1 
ATOM   1519 C  CB  . PHE A 1 192 ? 152.688 146.456 118.628 1.00 63.60  ? 192 PHE A CB  1 
ATOM   1520 C  CG  . PHE A 1 192 ? 151.876 145.382 119.290 1.00 70.17  ? 192 PHE A CG  1 
ATOM   1521 C  CD1 . PHE A 1 192 ? 152.414 144.128 119.512 1.00 79.20  ? 192 PHE A CD1 1 
ATOM   1522 C  CD2 . PHE A 1 192 ? 150.583 145.633 119.710 1.00 72.37  ? 192 PHE A CD2 1 
ATOM   1523 C  CE1 . PHE A 1 192 ? 151.673 143.142 120.128 1.00 76.76  ? 192 PHE A CE1 1 
ATOM   1524 C  CE2 . PHE A 1 192 ? 149.839 144.650 120.325 1.00 73.44  ? 192 PHE A CE2 1 
ATOM   1525 C  CZ  . PHE A 1 192 ? 150.385 143.404 120.534 1.00 72.37  ? 192 PHE A CZ  1 
ATOM   1526 N  N   . PHE A 1 193 ? 150.792 146.837 116.109 1.00 72.76  ? 193 PHE A N   1 
ATOM   1527 C  CA  . PHE A 1 193 ? 149.562 146.578 115.366 1.00 62.23  ? 193 PHE A CA  1 
ATOM   1528 C  C   . PHE A 1 193 ? 149.865 145.982 113.995 1.00 65.42  ? 193 PHE A C   1 
ATOM   1529 O  O   . PHE A 1 193 ? 149.206 145.030 113.555 1.00 76.45  ? 193 PHE A O   1 
ATOM   1530 C  CB  . PHE A 1 193 ? 148.755 147.869 115.217 1.00 60.73  ? 193 PHE A CB  1 
ATOM   1531 C  CG  . PHE A 1 193 ? 147.946 148.231 116.429 1.00 62.57  ? 193 PHE A CG  1 
ATOM   1532 C  CD1 . PHE A 1 193 ? 147.900 147.392 117.528 1.00 63.15  ? 193 PHE A CD1 1 
ATOM   1533 C  CD2 . PHE A 1 193 ? 147.230 149.414 116.467 1.00 63.02  ? 193 PHE A CD2 1 
ATOM   1534 C  CE1 . PHE A 1 193 ? 147.154 147.728 118.639 1.00 69.99  ? 193 PHE A CE1 1 
ATOM   1535 C  CE2 . PHE A 1 193 ? 146.485 149.754 117.576 1.00 68.05  ? 193 PHE A CE2 1 
ATOM   1536 C  CZ  . PHE A 1 193 ? 146.445 148.910 118.663 1.00 73.38  ? 193 PHE A CZ  1 
ATOM   1537 N  N   . PHE A 1 194 ? 150.865 146.534 113.304 1.00 66.68  ? 194 PHE A N   1 
ATOM   1538 C  CA  . PHE A 1 194 ? 151.258 145.991 112.010 1.00 69.90  ? 194 PHE A CA  1 
ATOM   1539 C  C   . PHE A 1 194 ? 151.728 144.552 112.146 1.00 70.52  ? 194 PHE A C   1 
ATOM   1540 O  O   . PHE A 1 194 ? 151.454 143.719 111.282 1.00 80.15  ? 194 PHE A O   1 
ATOM   1541 C  CB  . PHE A 1 194 ? 152.360 146.837 111.374 1.00 72.20  ? 194 PHE A CB  1 
ATOM   1542 C  CG  . PHE A 1 194 ? 153.090 146.129 110.264 1.00 73.85  ? 194 PHE A CG  1 
ATOM   1543 C  CD1 . PHE A 1 194 ? 152.580 146.120 108.977 1.00 80.96  ? 194 PHE A CD1 1 
ATOM   1544 C  CD2 . PHE A 1 194 ? 154.267 145.438 110.510 1.00 64.35  ? 194 PHE A CD2 1 
ATOM   1545 C  CE1 . PHE A 1 194 ? 153.238 145.459 107.959 1.00 82.13  ? 194 PHE A CE1 1 
ATOM   1546 C  CE2 . PHE A 1 194 ? 154.925 144.775 109.496 1.00 70.81  ? 194 PHE A CE2 1 
ATOM   1547 C  CZ  . PHE A 1 194 ? 154.411 144.787 108.221 1.00 79.65  ? 194 PHE A CZ  1 
ATOM   1548 N  N   . TRP A 1 195 ? 152.485 144.253 113.205 1.00 65.96  ? 195 TRP A N   1 
ATOM   1549 C  CA  . TRP A 1 195 ? 152.971 142.890 113.387 1.00 63.90  ? 195 TRP A CA  1 
ATOM   1550 C  C   . TRP A 1 195 ? 151.819 141.914 113.586 1.00 63.13  ? 195 TRP A C   1 
ATOM   1551 O  O   . TRP A 1 195 ? 151.825 140.812 113.024 1.00 71.91  ? 195 TRP A O   1 
ATOM   1552 C  CB  . TRP A 1 195 ? 153.932 142.811 114.570 1.00 70.87  ? 195 TRP A CB  1 
ATOM   1553 C  CG  . TRP A 1 195 ? 154.281 141.400 114.914 1.00 69.41  ? 195 TRP A CG  1 
ATOM   1554 C  CD1 . TRP A 1 195 ? 155.152 140.587 114.253 1.00 74.84  ? 195 TRP A CD1 1 
ATOM   1555 C  CD2 . TRP A 1 195 ? 153.744 140.622 115.988 1.00 68.02  ? 195 TRP A CD2 1 
ATOM   1556 N  NE1 . TRP A 1 195 ? 155.199 139.355 114.855 1.00 70.33  ? 195 TRP A NE1 1 
ATOM   1557 C  CE2 . TRP A 1 195 ? 154.344 139.349 115.924 1.00 66.05  ? 195 TRP A CE2 1 
ATOM   1558 C  CE3 . TRP A 1 195 ? 152.821 140.880 117.003 1.00 71.38  ? 195 TRP A CE3 1 
ATOM   1559 C  CZ2 . TRP A 1 195 ? 154.049 138.339 116.834 1.00 63.46  ? 195 TRP A CZ2 1 
ATOM   1560 C  CZ3 . TRP A 1 195 ? 152.528 139.877 117.904 1.00 76.76  ? 195 TRP A CZ3 1 
ATOM   1561 C  CH2 . TRP A 1 195 ? 153.140 138.622 117.814 1.00 69.72  ? 195 TRP A CH2 1 
ATOM   1562 N  N   . THR A 1 196 ? 150.824 142.296 114.389 1.00 66.03  ? 196 THR A N   1 
ATOM   1563 C  CA  . THR A 1 196 ? 149.658 141.426 114.544 1.00 68.04  ? 196 THR A CA  1 
ATOM   1564 C  C   . THR A 1 196 ? 148.925 141.236 113.221 1.00 70.72  ? 196 THR A C   1 
ATOM   1565 O  O   . THR A 1 196 ? 148.529 140.111 112.885 1.00 75.73  ? 196 THR A O   1 
ATOM   1566 C  CB  . THR A 1 196 ? 148.704 141.979 115.603 1.00 67.07  ? 196 THR A CB  1 
ATOM   1567 O  OG1 . THR A 1 196 ? 148.144 143.217 115.152 1.00 81.46  ? 196 THR A OG1 1 
ATOM   1568 C  CG2 . THR A 1 196 ? 149.430 142.194 116.920 1.00 69.39  ? 196 THR A CG2 1 
ATOM   1569 N  N   . SER A 1 197 ? 148.754 142.314 112.451 1.00 71.20  ? 197 SER A N   1 
ATOM   1570 C  CA  . SER A 1 197 ? 148.096 142.197 111.154 1.00 67.07  ? 197 SER A CA  1 
ATOM   1571 C  C   . SER A 1 197 ? 148.885 141.293 110.209 1.00 73.67  ? 197 SER A C   1 
ATOM   1572 O  O   . SER A 1 197 ? 148.298 140.513 109.452 1.00 80.57  ? 197 SER A O   1 
ATOM   1573 C  CB  . SER A 1 197 ? 147.902 143.583 110.541 1.00 72.64  ? 197 SER A CB  1 
ATOM   1574 O  OG  . SER A 1 197 ? 147.983 143.537 109.129 1.00 74.32  ? 197 SER A OG  1 
ATOM   1575 N  N   . TRP A 1 198 ? 150.216 141.394 110.232 1.00 71.20  ? 198 TRP A N   1 
ATOM   1576 C  CA  . TRP A 1 198 ? 151.054 140.546 109.394 1.00 68.78  ? 198 TRP A CA  1 
ATOM   1577 C  C   . TRP A 1 198 ? 150.931 139.085 109.795 1.00 65.98  ? 198 TRP A C   1 
ATOM   1578 O  O   . TRP A 1 198 ? 150.851 138.201 108.936 1.00 67.24  ? 198 TRP A O   1 
ATOM   1579 C  CB  . TRP A 1 198 ? 152.512 141.003 109.476 1.00 75.70  ? 198 TRP A CB  1 
ATOM   1580 C  CG  . TRP A 1 198 ? 153.493 140.029 108.891 1.00 69.22  ? 198 TRP A CG  1 
ATOM   1581 C  CD1 . TRP A 1 198 ? 153.942 139.994 107.606 1.00 74.15  ? 198 TRP A CD1 1 
ATOM   1582 C  CD2 . TRP A 1 198 ? 154.152 138.954 109.575 1.00 72.09  ? 198 TRP A CD2 1 
ATOM   1583 N  NE1 . TRP A 1 198 ? 154.832 138.963 107.443 1.00 77.40  ? 198 TRP A NE1 1 
ATOM   1584 C  CE2 . TRP A 1 198 ? 154.979 138.309 108.637 1.00 76.29  ? 198 TRP A CE2 1 
ATOM   1585 C  CE3 . TRP A 1 198 ? 154.119 138.475 110.887 1.00 76.10  ? 198 TRP A CE3 1 
ATOM   1586 C  CZ2 . TRP A 1 198 ? 155.766 137.210 108.968 1.00 79.44  ? 198 TRP A CZ2 1 
ATOM   1587 C  CZ3 . TRP A 1 198 ? 154.899 137.383 111.212 1.00 75.53  ? 198 TRP A CZ3 1 
ATOM   1588 C  CH2 . TRP A 1 198 ? 155.712 136.764 110.259 1.00 78.01  ? 198 TRP A CH2 1 
ATOM   1589 N  N   . SER A 1 199 ? 150.924 138.810 111.099 1.00 63.99  ? 199 SER A N   1 
ATOM   1590 C  CA  . SER A 1 199 ? 150.767 137.440 111.562 1.00 62.03  ? 199 SER A CA  1 
ATOM   1591 C  C   . SER A 1 199 ? 149.389 136.882 111.241 1.00 65.79  ? 199 SER A C   1 
ATOM   1592 O  O   . SER A 1 199 ? 149.242 135.662 111.119 1.00 76.04  ? 199 SER A O   1 
ATOM   1593 C  CB  . SER A 1 199 ? 151.028 137.354 113.066 1.00 74.06  ? 199 SER A CB  1 
ATOM   1594 O  OG  . SER A 1 199 ? 149.891 137.758 113.804 1.00 74.53  ? 199 SER A OG  1 
ATOM   1595 N  N   . ALA A 1 200 ? 148.382 137.741 111.095 1.00 72.60  ? 200 ALA A N   1 
ATOM   1596 C  CA  . ALA A 1 200 ? 147.040 137.292 110.752 1.00 68.76  ? 200 ALA A CA  1 
ATOM   1597 C  C   . ALA A 1 200 ? 146.827 137.119 109.253 1.00 69.14  ? 200 ALA A C   1 
ATOM   1598 O  O   . ALA A 1 200 ? 145.751 136.671 108.845 1.00 64.09  ? 200 ALA A O   1 
ATOM   1599 C  CB  . ALA A 1 200 ? 146.003 138.268 111.310 1.00 67.17  ? 200 ALA A CB  1 
ATOM   1600 N  N   . SER A 1 201 ? 147.816 137.453 108.420 1.00 75.00  ? 201 SER A N   1 
ATOM   1601 C  CA  . SER A 1 201 ? 147.625 137.442 106.975 1.00 67.14  ? 201 SER A CA  1 
ATOM   1602 C  C   . SER A 1 201 ? 148.760 136.764 106.218 1.00 77.20  ? 201 SER A C   1 
ATOM   1603 O  O   . SER A 1 201 ? 148.784 136.825 104.986 1.00 87.22  ? 201 SER A O   1 
ATOM   1604 C  CB  . SER A 1 201 ? 147.450 138.871 106.450 1.00 70.73  ? 201 SER A CB  1 
ATOM   1605 O  OG  . SER A 1 201 ? 148.288 139.776 107.144 1.00 84.44  ? 201 SER A OG  1 
ATOM   1606 N  N   . THR A 1 202 ? 149.693 136.119 106.910 1.00 78.52  ? 202 THR A N   1 
ATOM   1607 C  CA  . THR A 1 202 ? 150.841 135.480 106.281 1.00 72.90  ? 202 THR A CA  1 
ATOM   1608 C  C   . THR A 1 202 ? 150.772 133.982 106.535 1.00 82.38  ? 202 THR A C   1 
ATOM   1609 O  O   . THR A 1 202 ? 150.565 133.554 107.673 1.00 92.40  ? 202 THR A O   1 
ATOM   1610 C  CB  . THR A 1 202 ? 152.151 136.061 106.821 1.00 79.49  ? 202 THR A CB  1 
ATOM   1611 O  OG1 . THR A 1 202 ? 152.327 137.387 106.316 1.00 83.84  ? 202 THR A OG1 1 
ATOM   1612 C  CG2 . THR A 1 202 ? 153.334 135.215 106.391 1.00 81.29  ? 202 THR A CG2 1 
ATOM   1613 N  N   . ASN A 1 203 ? 150.947 133.191 105.478 1.00 85.68  ? 203 ASN A N   1 
ATOM   1614 C  CA  . ASN A 1 203 ? 150.849 131.744 105.599 1.00 80.57  ? 203 ASN A CA  1 
ATOM   1615 C  C   . ASN A 1 203 ? 151.960 131.187 106.481 1.00 86.09  ? 203 ASN A C   1 
ATOM   1616 O  O   . ASN A 1 203 ? 153.047 131.764 106.582 1.00 85.87  ? 203 ASN A O   1 
ATOM   1617 C  CB  . ASN A 1 203 ? 150.907 131.078 104.225 1.00 78.16  ? 203 ASN A CB  1 
ATOM   1618 C  CG  . ASN A 1 203 ? 149.613 131.215 103.455 1.00 88.43  ? 203 ASN A CG  1 
ATOM   1619 O  OD1 . ASN A 1 203 ? 148.529 131.181 104.032 1.00 98.45  ? 203 ASN A OD1 1 
ATOM   1620 N  ND2 . ASN A 1 203 ? 149.717 131.348 102.140 1.00 85.19  ? 203 ASN A ND2 1 
ATOM   1621 N  N   . ARG A 1 204 ? 151.676 130.058 107.121 1.00 96.87  ? 204 ARG A N   1 
ATOM   1622 C  CA  . ARG A 1 204 ? 152.673 129.370 107.920 1.00 93.63  ? 204 ARG A CA  1 
ATOM   1623 C  C   . ARG A 1 204 ? 153.754 128.790 107.010 1.00 101.02 ? 204 ARG A C   1 
ATOM   1624 O  O   . ARG A 1 204 ? 153.536 128.627 105.806 1.00 108.66 ? 204 ARG A O   1 
ATOM   1625 C  CB  . ARG A 1 204 ? 152.017 128.264 108.746 1.00 91.77  ? 204 ARG A CB  1 
ATOM   1626 C  CG  . ARG A 1 204 ? 151.288 128.769 109.977 1.00 92.12  ? 204 ARG A CG  1 
ATOM   1627 C  CD  . ARG A 1 204 ? 150.664 127.632 110.765 1.00 89.96  ? 204 ARG A CD  1 
ATOM   1628 N  NE  . ARG A 1 204 ? 150.263 128.048 112.104 1.00 88.13  ? 204 ARG A NE  1 
ATOM   1629 C  CZ  . ARG A 1 204 ? 151.104 128.315 113.095 1.00 92.24  ? 204 ARG A CZ  1 
ATOM   1630 N  NH1 . ARG A 1 204 ? 152.410 128.182 112.949 1.00 94.64  ? 204 ARG A NH1 1 
ATOM   1631 N  NH2 . ARG A 1 204 ? 150.618 128.719 114.264 1.00 96.26  ? 204 ARG A NH2 1 
ATOM   1632 N  N   . PRO A 1 205 ? 154.943 128.488 107.558 1.00 110.97 ? 205 PRO A N   1 
ATOM   1633 C  CA  . PRO A 1 205 ? 156.066 128.047 106.715 1.00 113.60 ? 205 PRO A CA  1 
ATOM   1634 C  C   . PRO A 1 205 ? 155.748 126.913 105.751 1.00 113.55 ? 205 PRO A C   1 
ATOM   1635 O  O   . PRO A 1 205 ? 156.224 126.927 104.611 1.00 117.31 ? 205 PRO A O   1 
ATOM   1636 C  CB  . PRO A 1 205 ? 157.111 127.600 107.745 1.00 113.97 ? 205 PRO A CB  1 
ATOM   1637 C  CG  . PRO A 1 205 ? 156.777 128.328 109.002 1.00 109.49 ? 205 PRO A CG  1 
ATOM   1638 C  CD  . PRO A 1 205 ? 155.393 128.900 108.897 1.00 105.63 ? 205 PRO A CD  1 
ATOM   1639 N  N   . ASP A 1 206 ? 154.962 125.931 106.177 1.00 128.95 ? 206 ASP A N   1 
ATOM   1640 C  CA  . ASP A 1 206 ? 154.669 124.767 105.350 1.00 131.09 ? 206 ASP A CA  1 
ATOM   1641 C  C   . ASP A 1 206 ? 153.172 124.510 105.274 1.00 131.65 ? 206 ASP A C   1 
ATOM   1642 O  O   . ASP A 1 206 ? 152.724 123.362 105.207 1.00 135.20 ? 206 ASP A O   1 
ATOM   1643 C  CB  . ASP A 1 206 ? 155.396 123.531 105.870 1.00 132.76 ? 206 ASP A CB  1 
ATOM   1644 C  CG  . ASP A 1 206 ? 156.840 123.467 105.411 1.00 135.21 ? 206 ASP A CG  1 
ATOM   1645 O  OD1 . ASP A 1 206 ? 157.074 123.437 104.186 1.00 135.42 ? 206 ASP A OD1 1 
ATOM   1646 O  OD2 . ASP A 1 206 ? 157.740 123.446 106.276 1.00 134.46 ? 206 ASP A OD2 1 
ATOM   1647 N  N   . GLU A 1 207 ? 152.372 125.573 105.281 1.00 115.30 ? 207 GLU A N   1 
ATOM   1648 C  CA  . GLU A 1 207 ? 150.922 125.447 105.227 1.00 113.91 ? 207 GLU A CA  1 
ATOM   1649 C  C   . GLU A 1 207 ? 150.356 126.508 104.295 1.00 113.34 ? 207 GLU A C   1 
ATOM   1650 O  O   . GLU A 1 207 ? 151.032 127.477 103.940 1.00 116.95 ? 207 GLU A O   1 
ATOM   1651 C  CB  . GLU A 1 207 ? 150.284 125.574 106.619 1.00 110.50 ? 207 GLU A CB  1 
ATOM   1652 C  CG  . GLU A 1 207 ? 150.979 124.770 107.707 1.00 116.74 ? 207 GLU A CG  1 
ATOM   1653 C  CD  . GLU A 1 207 ? 150.403 123.378 107.869 1.00 118.41 ? 207 GLU A CD  1 
ATOM   1654 O  OE1 . GLU A 1 207 ? 149.945 122.799 106.863 1.00 119.41 ? 207 GLU A OE1 1 
ATOM   1655 O  OE2 . GLU A 1 207 ? 150.413 122.859 109.004 1.00 116.46 ? 207 GLU A OE2 1 
ATOM   1656 N  N   . THR A 1 208 ? 149.101 126.307 103.892 1.00 97.54  ? 208 THR A N   1 
ATOM   1657 C  CA  . THR A 1 208 ? 148.391 127.238 103.024 1.00 97.96  ? 208 THR A CA  1 
ATOM   1658 C  C   . THR A 1 208 ? 147.433 128.136 103.798 1.00 98.35  ? 208 THR A C   1 
ATOM   1659 O  O   . THR A 1 208 ? 146.594 128.812 103.195 1.00 101.59 ? 208 THR A O   1 
ATOM   1660 C  CB  . THR A 1 208 ? 147.637 126.485 101.929 1.00 98.37  ? 208 THR A CB  1 
ATOM   1661 O  OG1 . THR A 1 208 ? 147.024 125.316 102.483 1.00 103.25 ? 208 THR A OG1 1 
ATOM   1662 C  CG2 . THR A 1 208 ? 148.584 126.073 100.820 1.00 97.93  ? 208 THR A CG2 1 
ATOM   1663 N  N   . PHE A 1 209 ? 147.535 128.150 105.124 1.00 93.69  ? 209 PHE A N   1 
ATOM   1664 C  CA  . PHE A 1 209 ? 146.736 129.030 105.962 1.00 91.26  ? 209 PHE A CA  1 
ATOM   1665 C  C   . PHE A 1 209 ? 147.658 129.825 106.874 1.00 93.59  ? 209 PHE A C   1 
ATOM   1666 O  O   . PHE A 1 209 ? 148.812 129.451 107.095 1.00 101.29 ? 209 PHE A O   1 
ATOM   1667 C  CB  . PHE A 1 209 ? 145.700 128.250 106.790 1.00 91.65  ? 209 PHE A CB  1 
ATOM   1668 C  CG  . PHE A 1 209 ? 146.259 127.049 107.496 1.00 92.52  ? 209 PHE A CG  1 
ATOM   1669 C  CD1 . PHE A 1 209 ? 146.864 127.174 108.734 1.00 93.39  ? 209 PHE A CD1 1 
ATOM   1670 C  CD2 . PHE A 1 209 ? 146.173 125.794 106.924 1.00 96.28  ? 209 PHE A CD2 1 
ATOM   1671 C  CE1 . PHE A 1 209 ? 147.375 126.073 109.384 1.00 97.57  ? 209 PHE A CE1 1 
ATOM   1672 C  CE2 . PHE A 1 209 ? 146.682 124.688 107.570 1.00 97.74  ? 209 PHE A CE2 1 
ATOM   1673 C  CZ  . PHE A 1 209 ? 147.283 124.828 108.802 1.00 98.62  ? 209 PHE A CZ  1 
ATOM   1674 N  N   . THR A 1 210 ? 147.140 130.935 107.391 1.00 80.95  ? 210 THR A N   1 
ATOM   1675 C  CA  . THR A 1 210 ? 147.962 131.857 108.159 1.00 80.27  ? 210 THR A CA  1 
ATOM   1676 C  C   . THR A 1 210 ? 148.199 131.333 109.575 1.00 80.40  ? 210 THR A C   1 
ATOM   1677 O  O   . THR A 1 210 ? 147.686 130.288 109.982 1.00 83.60  ? 210 THR A O   1 
ATOM   1678 C  CB  . THR A 1 210 ? 147.314 133.240 108.210 1.00 82.25  ? 210 THR A CB  1 
ATOM   1679 O  OG1 . THR A 1 210 ? 146.255 133.244 109.172 1.00 90.25  ? 210 THR A OG1 1 
ATOM   1680 C  CG2 . THR A 1 210 ? 146.764 133.621 106.849 1.00 85.34  ? 210 THR A CG2 1 
ATOM   1681 N  N   . TYR A 1 211 ? 149.003 132.087 110.329 1.00 70.52  ? 211 TYR A N   1 
ATOM   1682 C  CA  . TYR A 1 211 ? 149.310 131.731 111.709 1.00 68.70  ? 211 TYR A CA  1 
ATOM   1683 C  C   . TYR A 1 211 ? 148.078 131.741 112.602 1.00 76.85  ? 211 TYR A C   1 
ATOM   1684 O  O   . TYR A 1 211 ? 148.078 131.073 113.641 1.00 84.42  ? 211 TYR A O   1 
ATOM   1685 C  CB  . TYR A 1 211 ? 150.353 132.692 112.283 1.00 70.14  ? 211 TYR A CB  1 
ATOM   1686 C  CG  . TYR A 1 211 ? 151.747 132.509 111.734 1.00 73.08  ? 211 TYR A CG  1 
ATOM   1687 C  CD1 . TYR A 1 211 ? 152.175 133.227 110.627 1.00 79.42  ? 211 TYR A CD1 1 
ATOM   1688 C  CD2 . TYR A 1 211 ? 152.637 131.628 112.327 1.00 78.71  ? 211 TYR A CD2 1 
ATOM   1689 C  CE1 . TYR A 1 211 ? 153.448 133.068 110.123 1.00 80.35  ? 211 TYR A CE1 1 
ATOM   1690 C  CE2 . TYR A 1 211 ? 153.912 131.461 111.829 1.00 77.78  ? 211 TYR A CE2 1 
ATOM   1691 C  CZ  . TYR A 1 211 ? 154.312 132.183 110.728 1.00 79.52  ? 211 TYR A CZ  1 
ATOM   1692 O  OH  . TYR A 1 211 ? 155.581 132.022 110.229 1.00 84.01  ? 211 TYR A OH  1 
ATOM   1693 N  N   . THR A 1 212 ? 147.035 132.479 112.226 1.00 78.10  ? 212 THR A N   1 
ATOM   1694 C  CA  . THR A 1 212 ? 145.824 132.605 113.025 1.00 80.61  ? 212 THR A CA  1 
ATOM   1695 C  C   . THR A 1 212 ? 144.686 131.744 112.491 1.00 78.74  ? 212 THR A C   1 
ATOM   1696 O  O   . THR A 1 212 ? 143.518 132.010 112.792 1.00 85.39  ? 212 THR A O   1 
ATOM   1697 C  CB  . THR A 1 212 ? 145.390 134.068 113.097 1.00 77.79  ? 212 THR A CB  1 
ATOM   1698 O  OG1 . THR A 1 212 ? 145.040 134.530 111.788 1.00 85.61  ? 212 THR A OG1 1 
ATOM   1699 C  CG2 . THR A 1 212 ? 146.513 134.930 113.646 1.00 76.72  ? 212 THR A CG2 1 
ATOM   1700 N  N   . ASN A 1 213 ? 145.010 130.711 111.712 1.00 74.14  ? 213 ASN A N   1 
ATOM   1701 C  CA  . ASN A 1 213 ? 144.011 129.846 111.080 1.00 76.38  ? 213 ASN A CA  1 
ATOM   1702 C  C   . ASN A 1 213 ? 143.040 130.658 110.229 1.00 77.83  ? 213 ASN A C   1 
ATOM   1703 O  O   . ASN A 1 213 ? 141.825 130.450 110.263 1.00 87.12  ? 213 ASN A O   1 
ATOM   1704 C  CB  . ASN A 1 213 ? 143.259 129.012 112.120 1.00 75.69  ? 213 ASN A CB  1 
ATOM   1705 C  CG  . ASN A 1 213 ? 144.090 127.870 112.664 1.00 83.18  ? 213 ASN A CG  1 
ATOM   1706 O  OD1 . ASN A 1 213 ? 144.559 127.017 111.913 1.00 87.08  ? 213 ASN A OD1 1 
ATOM   1707 N  ND2 . ASN A 1 213 ? 144.271 127.845 113.978 1.00 84.03  ? 213 ASN A ND2 1 
ATOM   1708 N  N   . ASN A 1 214 ? 143.588 131.603 109.463 1.00 70.61  ? 214 ASN A N   1 
ATOM   1709 C  CA  . ASN A 1 214 ? 142.890 132.483 108.529 1.00 72.60  ? 214 ASN A CA  1 
ATOM   1710 C  C   . ASN A 1 214 ? 141.987 133.499 109.217 1.00 73.99  ? 214 ASN A C   1 
ATOM   1711 O  O   . ASN A 1 214 ? 141.160 134.119 108.543 1.00 80.79  ? 214 ASN A O   1 
ATOM   1712 C  CB  . ASN A 1 214 ? 142.057 131.706 107.499 1.00 74.27  ? 214 ASN A CB  1 
ATOM   1713 C  CG  . ASN A 1 214 ? 142.895 131.151 106.369 1.00 83.86  ? 214 ASN A CG  1 
ATOM   1714 O  OD1 . ASN A 1 214 ? 144.115 131.300 106.356 1.00 83.09  ? 214 ASN A OD1 1 
ATOM   1715 N  ND2 . ASN A 1 214 ? 142.244 130.505 105.412 1.00 85.93  ? 214 ASN A ND2 1 
ATOM   1716 N  N   . TRP A 1 215 ? 142.102 133.682 110.525 1.00 60.93  ? 215 TRP A N   1 
ATOM   1717 C  CA  . TRP A 1 215 ? 141.358 134.739 111.191 1.00 56.87  ? 215 TRP A CA  1 
ATOM   1718 C  C   . TRP A 1 215 ? 142.060 136.079 110.980 1.00 68.22  ? 215 TRP A C   1 
ATOM   1719 O  O   . TRP A 1 215 ? 143.294 136.140 110.982 1.00 83.66  ? 215 TRP A O   1 
ATOM   1720 C  CB  . TRP A 1 215 ? 141.238 134.438 112.683 1.00 59.86  ? 215 TRP A CB  1 
ATOM   1721 C  CG  . TRP A 1 215 ? 140.282 135.321 113.414 1.00 66.33  ? 215 TRP A CG  1 
ATOM   1722 C  CD1 . TRP A 1 215 ? 138.972 135.063 113.681 1.00 68.92  ? 215 TRP A CD1 1 
ATOM   1723 C  CD2 . TRP A 1 215 ? 140.561 136.607 113.976 1.00 69.58  ? 215 TRP A CD2 1 
ATOM   1724 N  NE1 . TRP A 1 215 ? 138.416 136.111 114.372 1.00 68.03  ? 215 TRP A NE1 1 
ATOM   1725 C  CE2 . TRP A 1 215 ? 139.370 137.072 114.563 1.00 70.94  ? 215 TRP A CE2 1 
ATOM   1726 C  CE3 . TRP A 1 215 ? 141.701 137.414 114.033 1.00 70.24  ? 215 TRP A CE3 1 
ATOM   1727 C  CZ2 . TRP A 1 215 ? 139.288 138.304 115.202 1.00 70.12  ? 215 TRP A CZ2 1 
ATOM   1728 C  CZ3 . TRP A 1 215 ? 141.614 138.636 114.663 1.00 69.84  ? 215 TRP A CZ3 1 
ATOM   1729 C  CH2 . TRP A 1 215 ? 140.419 139.070 115.242 1.00 67.28  ? 215 TRP A CH2 1 
ATOM   1730 N  N   . PRO A 1 216 ? 141.310 137.177 110.804 1.00 58.55  ? 216 PRO A N   1 
ATOM   1731 C  CA  . PRO A 1 216 ? 139.848 137.295 110.750 1.00 61.84  ? 216 PRO A CA  1 
ATOM   1732 C  C   . PRO A 1 216 ? 139.293 137.086 109.352 1.00 64.85  ? 216 PRO A C   1 
ATOM   1733 O  O   . PRO A 1 216 ? 140.045 136.982 108.395 1.00 77.65  ? 216 PRO A O   1 
ATOM   1734 C  CB  . PRO A 1 216 ? 139.618 138.724 111.244 1.00 66.45  ? 216 PRO A CB  1 
ATOM   1735 C  CG  . PRO A 1 216 ? 140.796 139.475 110.693 1.00 63.10  ? 216 PRO A CG  1 
ATOM   1736 C  CD  . PRO A 1 216 ? 141.956 138.498 110.701 1.00 56.17  ? 216 PRO A CD  1 
ATOM   1737 N  N   . HIS A 1 217 ? 137.970 137.038 109.211 1.00 57.57  ? 217 HIS A N   1 
ATOM   1738 C  CA  . HIS A 1 217 ? 137.341 136.884 107.905 1.00 63.27  ? 217 HIS A CA  1 
ATOM   1739 C  C   . HIS A 1 217 ? 137.632 138.089 107.020 1.00 74.28  ? 217 HIS A C   1 
ATOM   1740 O  O   . HIS A 1 217 ? 137.082 139.174 107.238 1.00 83.82  ? 217 HIS A O   1 
ATOM   1741 C  CB  . HIS A 1 217 ? 135.832 136.692 108.065 1.00 58.25  ? 217 HIS A CB  1 
ATOM   1742 C  CG  . HIS A 1 217 ? 135.105 136.509 106.771 1.00 67.87  ? 217 HIS A CG  1 
ATOM   1743 N  ND1 . HIS A 1 217 ? 133.795 136.895 106.593 1.00 65.49  ? 217 HIS A ND1 1 
ATOM   1744 C  CD2 . HIS A 1 217 ? 135.504 135.977 105.592 1.00 79.05  ? 217 HIS A CD2 1 
ATOM   1745 C  CE1 . HIS A 1 217 ? 133.419 136.612 105.359 1.00 72.41  ? 217 HIS A CE1 1 
ATOM   1746 N  NE2 . HIS A 1 217 ? 134.438 136.054 104.731 1.00 73.49  ? 217 HIS A NE2 1 
ATOM   1747 N  N   . GLU A 1 218 ? 138.369 137.853 105.993 1.00 79.22  ? 218 GLU A N   1 
ATOM   1748 C  CA  . GLU A 1 218 ? 138.803 138.987 105.193 1.00 77.75  ? 218 GLU A CA  1 
ATOM   1749 C  C   . GLU A 1 218 ? 138.765 138.515 103.740 1.00 86.66  ? 218 GLU A C   1 
ATOM   1750 O  O   . GLU A 1 218 ? 139.723 137.893 103.344 1.00 95.42  ? 218 GLU A O   1 
ATOM   1751 C  CB  . GLU A 1 218 ? 140.075 139.594 105.835 1.00 81.68  ? 218 GLU A CB  1 
ATOM   1752 C  CG  . GLU A 1 218 ? 140.699 140.709 105.022 1.00 84.87  ? 218 GLU A CG  1 
ATOM   1753 C  CD  . GLU A 1 218 ? 139.823 141.890 104.636 1.00 93.15  ? 218 GLU A CD  1 
ATOM   1754 O  OE1 . GLU A 1 218 ? 139.779 142.865 105.394 1.00 96.94  ? 218 GLU A OE1 1 
ATOM   1755 O  OE2 . GLU A 1 218 ? 139.221 141.851 103.569 1.00 94.35  ? 218 GLU A OE2 1 
ATOM   1756 N  N   . PRO A 1 219 ? 137.640 138.759 103.045 1.00 78.52  ? 219 PRO A N   1 
ATOM   1757 C  CA  . PRO A 1 219 ? 137.473 138.318 101.659 1.00 85.11  ? 219 PRO A CA  1 
ATOM   1758 C  C   . PRO A 1 219 ? 138.515 138.829 100.657 1.00 85.79  ? 219 PRO A C   1 
ATOM   1759 O  O   . PRO A 1 219 ? 138.723 138.178 99.706  1.00 93.97  ? 219 PRO A O   1 
ATOM   1760 C  CB  . PRO A 1 219 ? 136.032 138.820 101.361 1.00 84.87  ? 219 PRO A CB  1 
ATOM   1761 C  CG  . PRO A 1 219 ? 135.351 138.847 102.693 1.00 83.04  ? 219 PRO A CG  1 
ATOM   1762 C  CD  . PRO A 1 219 ? 136.427 139.395 103.589 1.00 76.14  ? 219 PRO A CD  1 
ATOM   1763 N  N   . LEU A 1 220 ? 139.136 139.945 100.966 1.00 80.86  ? 220 LEU A N   1 
ATOM   1764 C  CA  . LEU A 1 220 ? 140.124 140.517 100.057 1.00 82.43  ? 220 LEU A CA  1 
ATOM   1765 C  C   . LEU A 1 220 ? 141.316 139.589 99.862  1.00 85.12  ? 220 LEU A C   1 
ATOM   1766 O  O   . LEU A 1 220 ? 141.811 139.446 98.737  1.00 90.64  ? 220 LEU A O   1 
ATOM   1767 C  CB  . LEU A 1 220 ? 140.589 141.877 100.575 1.00 82.86  ? 220 LEU A CB  1 
ATOM   1768 C  CG  . LEU A 1 220 ? 139.609 143.039 100.405 1.00 84.35  ? 220 LEU A CG  1 
ATOM   1769 C  CD1 . LEU A 1 220 ? 140.164 144.305 101.036 1.00 83.71  ? 220 LEU A CD1 1 
ATOM   1770 C  CD2 . LEU A 1 220 ? 139.293 143.263 98.938  1.00 84.70  ? 220 LEU A CD2 1 
ATOM   1771 N  N   . ILE A 1 221 ? 141.764 138.902 100.903 1.00 72.93  ? 221 ILE A N   1 
ATOM   1772 C  CA  . ILE A 1 221 ? 142.931 137.990 100.855 1.00 78.15  ? 221 ILE A CA  1 
ATOM   1773 C  C   . ILE A 1 221 ? 142.432 136.572 101.061 1.00 84.67  ? 221 ILE A C   1 
ATOM   1774 O  O   . ILE A 1 221 ? 143.271 135.712 101.248 1.00 83.99  ? 221 ILE A O   1 
ATOM   1775 C  CB  . ILE A 1 221 ? 144.054 138.455 101.822 1.00 72.04  ? 221 ILE A CB  1 
ATOM   1776 C  CG1 . ILE A 1 221 ? 143.568 138.635 103.266 1.00 80.12  ? 221 ILE A CG1 1 
ATOM   1777 C  CG2 . ILE A 1 221 ? 144.751 139.690 101.281 1.00 76.63  ? 221 ILE A CG2 1 
ATOM   1778 C  CD1 . ILE A 1 221 ? 144.544 138.157 104.307 1.00 80.09  ? 221 ILE A CD1 1 
ATOM   1779 N  N   . ASN A 1 222 ? 141.113 136.345 101.011 1.00 89.04  ? 222 ASN A N   1 
ATOM   1780 C  CA  . ASN A 1 222 ? 140.552 134.995 101.098 1.00 85.75  ? 222 ASN A CA  1 
ATOM   1781 C  C   . ASN A 1 222 ? 140.855 134.363 102.453 1.00 85.23  ? 222 ASN A C   1 
ATOM   1782 O  O   . ASN A 1 222 ? 141.214 133.188 102.545 1.00 92.77  ? 222 ASN A O   1 
ATOM   1783 C  CB  . ASN A 1 222 ? 141.057 134.101 99.962  1.00 85.03  ? 222 ASN A CB  1 
ATOM   1784 C  CG  . ASN A 1 222 ? 140.539 134.531 98.609  1.00 90.60  ? 222 ASN A CG  1 
ATOM   1785 O  OD1 . ASN A 1 222 ? 141.314 134.834 97.704  1.00 95.61  ? 222 ASN A OD1 1 
ATOM   1786 N  ND2 . ASN A 1 222 ? 139.220 134.557 98.461  1.00 89.20  ? 222 ASN A ND2 1 
ATOM   1787 N  N   . ASN A 1 223 ? 140.716 135.154 103.514 1.00 70.59  ? 223 ASN A N   1 
ATOM   1788 C  CA  . ASN A 1 223 ? 140.876 134.660 104.878 1.00 69.00  ? 223 ASN A CA  1 
ATOM   1789 C  C   . ASN A 1 223 ? 139.556 134.010 105.287 1.00 74.71  ? 223 ASN A C   1 
ATOM   1790 O  O   . ASN A 1 223 ? 138.709 134.600 105.963 1.00 81.84  ? 223 ASN A O   1 
ATOM   1791 C  CB  . ASN A 1 223 ? 141.277 135.790 105.812 1.00 69.63  ? 223 ASN A CB  1 
ATOM   1792 C  CG  . ASN A 1 223 ? 142.697 135.653 106.318 1.00 73.52  ? 223 ASN A CG  1 
ATOM   1793 O  OD1 . ASN A 1 223 ? 143.530 134.999 105.694 1.00 86.21  ? 223 ASN A OD1 1 
ATOM   1794 N  ND2 . ASN A 1 223 ? 142.982 136.272 107.455 1.00 73.28  ? 223 ASN A ND2 1 
ATOM   1795 N  N   . VAL A 1 224 ? 139.388 132.765 104.858 1.00 77.09  ? 224 VAL A N   1 
ATOM   1796 C  CA  . VAL A 1 224 ? 138.140 132.025 105.026 1.00 80.95  ? 224 VAL A CA  1 
ATOM   1797 C  C   . VAL A 1 224 ? 138.416 130.778 105.859 1.00 86.08  ? 224 VAL A C   1 
ATOM   1798 O  O   . VAL A 1 224 ? 139.578 130.364 105.972 1.00 95.37  ? 224 VAL A O   1 
ATOM   1799 C  CB  . VAL A 1 224 ? 137.526 131.668 103.662 1.00 82.61  ? 224 VAL A CB  1 
ATOM   1800 C  CG1 . VAL A 1 224 ? 137.118 132.928 102.923 1.00 82.62  ? 224 VAL A CG1 1 
ATOM   1801 C  CG2 . VAL A 1 224 ? 138.507 130.858 102.837 1.00 81.39  ? 224 VAL A CG2 1 
ATOM   1802 N  N   . PRO A 1 225 ? 137.402 130.157 106.467 1.00 77.37  ? 225 PRO A N   1 
ATOM   1803 C  CA  . PRO A 1 225 ? 137.652 128.953 107.269 1.00 76.56  ? 225 PRO A CA  1 
ATOM   1804 C  C   . PRO A 1 225 ? 138.256 127.836 106.431 1.00 79.02  ? 225 PRO A C   1 
ATOM   1805 O  O   . PRO A 1 225 ? 138.001 127.724 105.229 1.00 77.26  ? 225 PRO A O   1 
ATOM   1806 C  CB  . PRO A 1 225 ? 136.261 128.577 107.788 1.00 79.42  ? 225 PRO A CB  1 
ATOM   1807 C  CG  . PRO A 1 225 ? 135.491 129.834 107.747 1.00 82.08  ? 225 PRO A CG  1 
ATOM   1808 C  CD  . PRO A 1 225 ? 136.001 130.598 106.568 1.00 77.15  ? 225 PRO A CD  1 
ATOM   1809 N  N   . THR A 1 226 ? 139.215 127.143 107.025 1.00 89.34  ? 226 THR A N   1 
ATOM   1810 C  CA  . THR A 1 226 ? 139.930 126.002 106.398 1.00 89.85  ? 226 THR A CA  1 
ATOM   1811 C  C   . THR A 1 226 ? 139.161 124.672 106.463 1.00 99.87  ? 226 THR A C   1 
ATOM   1812 O  O   . THR A 1 226 ? 138.200 124.611 107.206 1.00 106.28 ? 226 THR A O   1 
ATOM   1813 C  CB  . THR A 1 226 ? 141.336 126.002 107.028 1.00 88.46  ? 226 THR A CB  1 
ATOM   1814 O  OG1 . THR A 1 226 ? 141.285 125.469 108.351 1.00 98.62  ? 226 THR A OG1 1 
ATOM   1815 C  CG2 . THR A 1 226 ? 141.976 127.374 107.072 1.00 84.83  ? 226 THR A CG2 1 
ATOM   1816 N  N   . THR A 1 227 ? 139.541 123.660 105.689 1.00 101.25 ? 227 THR A N   1 
ATOM   1817 C  CA  . THR A 1 227 ? 138.939 122.332 105.675 1.00 100.39 ? 227 THR A CA  1 
ATOM   1818 C  C   . THR A 1 227 ? 139.045 121.665 107.037 1.00 99.61  ? 227 THR A C   1 
ATOM   1819 O  O   . THR A 1 227 ? 138.128 120.955 107.462 1.00 104.37 ? 227 THR A O   1 
ATOM   1820 C  CB  . THR A 1 227 ? 139.595 121.466 104.600 1.00 97.02  ? 227 THR A CB  1 
ATOM   1821 O  OG1 . THR A 1 227 ? 140.888 121.045 105.049 1.00 95.04  ? 227 THR A OG1 1 
ATOM   1822 C  CG2 . THR A 1 227 ? 139.743 122.246 103.306 1.00 97.89  ? 227 THR A CG2 1 
ATOM   1823 N  N   . GLU A 1 228 ? 140.164 121.873 107.738 1.00 104.14 ? 228 GLU A N   1 
ATOM   1824 C  CA  . GLU A 1 228 ? 140.276 121.380 109.106 1.00 108.79 ? 228 GLU A CA  1 
ATOM   1825 C  C   . GLU A 1 228 ? 139.217 122.003 110.001 1.00 110.38 ? 228 GLU A C   1 
ATOM   1826 O  O   . GLU A 1 228 ? 138.618 121.309 110.832 1.00 117.21 ? 228 GLU A O   1 
ATOM   1827 C  CB  . GLU A 1 228 ? 141.669 121.670 109.664 1.00 104.43 ? 228 GLU A CB  1 
ATOM   1828 C  CG  . GLU A 1 228 ? 142.790 120.898 108.994 1.00 113.60 ? 228 GLU A CG  1 
ATOM   1829 C  CD  . GLU A 1 228 ? 143.535 121.724 107.965 1.00 121.04 ? 228 GLU A CD  1 
ATOM   1830 O  OE1 . GLU A 1 228 ? 142.894 122.557 107.287 1.00 120.69 ? 228 GLU A OE1 1 
ATOM   1831 O  OE2 . GLU A 1 228 ? 144.763 121.540 107.832 1.00 120.14 ? 228 GLU A OE2 1 
ATOM   1832 N  N   . ASN A 1 229 ? 138.990 123.316 109.885 1.00 87.96  ? 229 ASN A N   1 
ATOM   1833 C  CA  . ASN A 1 229 ? 137.913 124.038 110.592 1.00 84.66  ? 229 ASN A CA  1 
ATOM   1834 C  C   . ASN A 1 229 ? 136.558 123.342 110.349 1.00 91.70  ? 229 ASN A C   1 
ATOM   1835 O  O   . ASN A 1 229 ? 135.959 122.985 111.343 1.00 96.23  ? 229 ASN A O   1 
ATOM   1836 C  CB  . ASN A 1 229 ? 137.987 125.529 110.273 1.00 83.58  ? 229 ASN A CB  1 
ATOM   1837 C  CG  . ASN A 1 229 ? 137.018 126.440 110.999 1.00 91.28  ? 229 ASN A CG  1 
ATOM   1838 O  OD1 . ASN A 1 229 ? 135.839 126.145 111.103 1.00 100.32 ? 229 ASN A OD1 1 
ATOM   1839 N  ND2 . ASN A 1 229 ? 137.482 127.598 111.430 1.00 91.54  ? 229 ASN A ND2 1 
ATOM   1840 N  N   . TYR A 1 230 ? 136.204 123.096 109.086 1.00 87.94  ? 230 TYR A N   1 
ATOM   1841 C  CA  . TYR A 1 230 ? 134.919 122.470 108.781 1.00 88.46  ? 230 TYR A CA  1 
ATOM   1842 C  C   . TYR A 1 230 ? 134.835 121.059 109.352 1.00 96.87  ? 230 TYR A C   1 
ATOM   1843 O  O   . TYR A 1 230 ? 133.831 120.691 109.981 1.00 104.18 ? 230 TYR A O   1 
ATOM   1844 C  CB  . TYR A 1 230 ? 134.694 122.440 107.271 1.00 83.47  ? 230 TYR A CB  1 
ATOM   1845 C  CG  . TYR A 1 230 ? 134.343 123.778 106.665 1.00 84.51  ? 230 TYR A CG  1 
ATOM   1846 C  CD1 . TYR A 1 230 ? 133.125 124.384 106.929 1.00 88.16  ? 230 TYR A CD1 1 
ATOM   1847 C  CD2 . TYR A 1 230 ? 135.232 124.433 105.827 1.00 89.46  ? 230 TYR A CD2 1 
ATOM   1848 C  CE1 . TYR A 1 230 ? 132.802 125.605 106.374 1.00 92.47  ? 230 TYR A CE1 1 
ATOM   1849 C  CE2 . TYR A 1 230 ? 134.921 125.654 105.268 1.00 91.07  ? 230 TYR A CE2 1 
ATOM   1850 C  CZ  . TYR A 1 230 ? 133.705 126.236 105.545 1.00 94.24  ? 230 TYR A CZ  1 
ATOM   1851 O  OH  . TYR A 1 230 ? 133.387 127.454 104.991 1.00 97.51  ? 230 TYR A OH  1 
ATOM   1852 N  N   . MET A 1 231 ? 135.908 120.309 109.194 1.00 97.31  ? 231 MET A N   1 
ATOM   1853 C  CA  . MET A 1 231 ? 136.023 118.894 109.583 1.00 94.73  ? 231 MET A CA  1 
ATOM   1854 C  C   . MET A 1 231 ? 135.890 118.691 111.082 1.00 96.74  ? 231 MET A C   1 
ATOM   1855 O  O   . MET A 1 231 ? 135.217 117.755 111.491 1.00 103.74 ? 231 MET A O   1 
ATOM   1856 C  CB  . MET A 1 231 ? 137.416 118.460 109.145 1.00 93.50  ? 231 MET A CB  1 
ATOM   1857 C  CG  . MET A 1 231 ? 137.450 117.137 108.448 1.00 101.17 ? 231 MET A CG  1 
ATOM   1858 S  SD  . MET A 1 231 ? 137.375 115.753 109.612 1.00 128.96 ? 231 MET A SD  1 
ATOM   1859 C  CE  . MET A 1 231 ? 138.438 116.338 110.931 1.00 102.41 ? 231 MET A CE  1 
ATOM   1860 N  N   . TRP A 1 232 ? 136.498 119.568 111.830 1.00 89.56  ? 232 TRP A N   1 
ATOM   1861 C  CA  . TRP A 1 232 ? 136.445 119.469 113.281 1.00 92.84  ? 232 TRP A CA  1 
ATOM   1862 C  C   . TRP A 1 232 ? 135.169 120.067 113.854 1.00 99.06  ? 232 TRP A C   1 
ATOM   1863 O  O   . TRP A 1 232 ? 134.680 119.583 114.878 1.00 105.83 ? 232 TRP A O   1 
ATOM   1864 C  CB  . TRP A 1 232 ? 137.689 120.110 113.895 1.00 95.66  ? 232 TRP A CB  1 
ATOM   1865 C  CG  . TRP A 1 232 ? 138.929 119.316 113.602 1.00 98.92  ? 232 TRP A CG  1 
ATOM   1866 C  CD1 . TRP A 1 232 ? 140.040 119.744 112.939 1.00 105.52 ? 232 TRP A CD1 1 
ATOM   1867 C  CD2 . TRP A 1 232 ? 139.173 117.947 113.949 1.00 97.93  ? 232 TRP A CD2 1 
ATOM   1868 N  NE1 . TRP A 1 232 ? 140.961 118.731 112.855 1.00 108.43 ? 232 TRP A NE1 1 
ATOM   1869 C  CE2 . TRP A 1 232 ? 140.452 117.616 113.467 1.00 102.80 ? 232 TRP A CE2 1 
ATOM   1870 C  CE3 . TRP A 1 232 ? 138.436 116.970 114.627 1.00 97.67  ? 232 TRP A CE3 1 
ATOM   1871 C  CZ2 . TRP A 1 232 ? 141.013 116.352 113.641 1.00 99.33  ? 232 TRP A CZ2 1 
ATOM   1872 C  CZ3 . TRP A 1 232 ? 138.992 115.717 114.794 1.00 95.86  ? 232 TRP A CZ3 1 
ATOM   1873 C  CH2 . TRP A 1 232 ? 140.268 115.420 114.304 1.00 98.73  ? 232 TRP A CH2 1 
ATOM   1874 N  N   . SER A 1 233 ? 134.591 121.085 113.208 1.00 94.14  ? 233 SER A N   1 
ATOM   1875 C  CA  . SER A 1 233 ? 133.279 121.556 113.641 1.00 94.91  ? 233 SER A CA  1 
ATOM   1876 C  C   . SER A 1 233 ? 132.222 120.470 113.472 1.00 99.62  ? 233 SER A C   1 
ATOM   1877 O  O   . SER A 1 233 ? 131.409 120.234 114.379 1.00 102.28 ? 233 SER A O   1 
ATOM   1878 C  CB  . SER A 1 233 ? 132.889 122.810 112.863 1.00 90.92  ? 233 SER A CB  1 
ATOM   1879 O  OG  . SER A 1 233 ? 133.898 123.796 112.954 1.00 97.48  ? 233 SER A OG  1 
ATOM   1880 N  N   . PHE A 1 234 ? 132.229 119.792 112.321 1.00 99.79  ? 234 PHE A N   1 
ATOM   1881 C  CA  . PHE A 1 234 ? 131.280 118.704 112.102 1.00 96.78  ? 234 PHE A CA  1 
ATOM   1882 C  C   . PHE A 1 234 ? 131.502 117.575 113.100 1.00 96.85  ? 234 PHE A C   1 
ATOM   1883 O  O   . PHE A 1 234 ? 130.538 117.011 113.636 1.00 102.53 ? 234 PHE A O   1 
ATOM   1884 C  CB  . PHE A 1 234 ? 131.400 118.199 110.665 1.00 97.92  ? 234 PHE A CB  1 
ATOM   1885 C  CG  . PHE A 1 234 ? 130.606 116.958 110.384 1.00 103.67 ? 234 PHE A CG  1 
ATOM   1886 C  CD1 . PHE A 1 234 ? 129.238 117.026 110.190 1.00 103.39 ? 234 PHE A CD1 1 
ATOM   1887 C  CD2 . PHE A 1 234 ? 131.227 115.724 110.301 1.00 101.57 ? 234 PHE A CD2 1 
ATOM   1888 C  CE1 . PHE A 1 234 ? 128.503 115.888 109.927 1.00 102.00 ? 234 PHE A CE1 1 
ATOM   1889 C  CE2 . PHE A 1 234 ? 130.499 114.582 110.037 1.00 100.41 ? 234 PHE A CE2 1 
ATOM   1890 C  CZ  . PHE A 1 234 ? 129.134 114.666 109.850 1.00 102.78 ? 234 PHE A CZ  1 
ATOM   1891 N  N   . THR A 1 235 ? 132.766 117.241 113.371 1.00 92.62  ? 235 THR A N   1 
ATOM   1892 C  CA  . THR A 1 235 ? 133.070 116.188 114.335 1.00 95.62  ? 235 THR A CA  1 
ATOM   1893 C  C   . THR A 1 235 ? 132.583 116.557 115.730 1.00 98.07  ? 235 THR A C   1 
ATOM   1894 O  O   . THR A 1 235 ? 132.026 115.714 116.441 1.00 103.28 ? 235 THR A O   1 
ATOM   1895 C  CB  . THR A 1 235 ? 134.573 115.909 114.344 1.00 100.29 ? 235 THR A CB  1 
ATOM   1896 O  OG1 . THR A 1 235 ? 134.948 115.279 113.115 1.00 103.69 ? 235 THR A OG1 1 
ATOM   1897 C  CG2 . THR A 1 235 ? 134.941 114.991 115.495 1.00 97.82  ? 235 THR A CG2 1 
ATOM   1898 N  N   . SER A 1 236 ? 132.780 117.811 116.140 1.00 100.61 ? 236 SER A N   1 
ATOM   1899 C  CA  . SER A 1 236 ? 132.321 118.239 117.458 1.00 102.31 ? 236 SER A CA  1 
ATOM   1900 C  C   . SER A 1 236 ? 130.803 118.183 117.564 1.00 104.67 ? 236 SER A C   1 
ATOM   1901 O  O   . SER A 1 236 ? 130.264 117.766 118.596 1.00 109.03 ? 236 SER A O   1 
ATOM   1902 C  CB  . SER A 1 236 ? 132.826 119.647 117.759 1.00 105.90 ? 236 SER A CB  1 
ATOM   1903 O  OG  . SER A 1 236 ? 132.041 120.621 117.096 1.00 108.00 ? 236 SER A OG  1 
ATOM   1904 N  N   . VAL A 1 237 ? 130.029 118.624 116.604 1.00 98.64  ? 237 VAL A N   1 
ATOM   1905 C  CA  . VAL A 1 237 ? 128.548 118.515 116.645 1.00 95.83  ? 237 VAL A CA  1 
ATOM   1906 C  C   . VAL A 1 237 ? 128.140 117.038 116.663 1.00 99.20  ? 237 VAL A C   1 
ATOM   1907 O  O   . VAL A 1 237 ? 127.230 116.701 117.389 1.00 104.73 ? 237 VAL A O   1 
ATOM   1908 C  CB  . VAL A 1 237 ? 127.919 119.305 115.483 1.00 98.16  ? 237 VAL A CB  1 
ATOM   1909 C  CG1 . VAL A 1 237 ? 126.405 119.179 115.460 1.00 97.94  ? 237 VAL A CG1 1 
ATOM   1910 C  CG2 . VAL A 1 237 ? 128.334 120.765 115.537 1.00 101.75 ? 237 VAL A CG2 1 
ATOM   1911 N  N   . VAL A 1 238 ? 128.784 116.201 115.862 1.00 102.48 ? 238 VAL A N   1 
ATOM   1912 C  CA  . VAL A 1 238 ? 128.412 114.789 115.906 1.00 101.78 ? 238 VAL A CA  1 
ATOM   1913 C  C   . VAL A 1 238 ? 128.684 114.208 117.287 1.00 102.06 ? 238 VAL A C   1 
ATOM   1914 O  O   . VAL A 1 238 ? 127.879 113.436 117.823 1.00 111.40 ? 238 VAL A O   1 
ATOM   1915 C  CB  . VAL A 1 238 ? 129.155 114.011 114.802 1.00 102.20 ? 238 VAL A CB  1 
ATOM   1916 C  CG1 . VAL A 1 238 ? 129.326 112.551 115.189 1.00 96.81  ? 238 VAL A CG1 1 
ATOM   1917 C  CG2 . VAL A 1 238 ? 128.412 114.132 113.484 1.00 105.92 ? 238 VAL A CG2 1 
ATOM   1918 N  N   . LEU A 1 239 ? 129.784 114.569 117.925 1.00 102.80 ? 239 LEU A N   1 
ATOM   1919 C  CA  . LEU A 1 239 ? 130.111 114.049 119.272 1.00 103.13 ? 239 LEU A CA  1 
ATOM   1920 C  C   . LEU A 1 239 ? 129.091 114.567 120.274 1.00 105.59 ? 239 LEU A C   1 
ATOM   1921 O  O   . LEU A 1 239 ? 128.674 113.796 121.130 1.00 113.21 ? 239 LEU A O   1 
ATOM   1922 C  CB  . LEU A 1 239 ? 131.492 114.527 119.704 1.00 104.33 ? 239 LEU A CB  1 
ATOM   1923 C  CG  . LEU A 1 239 ? 132.694 113.855 119.052 1.00 109.23 ? 239 LEU A CG  1 
ATOM   1924 C  CD1 . LEU A 1 239 ? 133.967 114.283 119.764 1.00 112.19 ? 239 LEU A CD1 1 
ATOM   1925 C  CD2 . LEU A 1 239 ? 132.550 112.341 119.058 1.00 111.23 ? 239 LEU A CD2 1 
ATOM   1926 N  N   . LEU A 1 240 ? 128.740 115.840 120.172 1.00 107.77 ? 240 LEU A N   1 
ATOM   1927 C  CA  . LEU A 1 240 ? 127.730 116.348 121.094 1.00 107.28 ? 240 LEU A CA  1 
ATOM   1928 C  C   . LEU A 1 240 ? 126.410 115.607 120.938 1.00 109.41 ? 240 LEU A C   1 
ATOM   1929 O  O   . LEU A 1 240 ? 125.767 115.262 121.938 1.00 116.46 ? 240 LEU A O   1 
ATOM   1930 C  CB  . LEU A 1 240 ? 127.517 117.846 120.879 1.00 108.81 ? 240 LEU A CB  1 
ATOM   1931 C  CG  . LEU A 1 240 ? 126.364 118.439 121.694 1.00 108.13 ? 240 LEU A CG  1 
ATOM   1932 C  CD1 . LEU A 1 240 ? 126.868 118.989 123.018 1.00 114.09 ? 240 LEU A CD1 1 
ATOM   1933 C  CD2 . LEU A 1 240 ? 125.615 119.502 120.912 1.00 104.80 ? 240 LEU A CD2 1 
ATOM   1934 N  N   . LEU A 1 241 ? 125.988 115.357 119.696 1.00 109.59 ? 241 LEU A N   1 
ATOM   1935 C  CA  . LEU A 1 241 ? 124.745 114.621 119.480 1.00 107.57 ? 241 LEU A CA  1 
ATOM   1936 C  C   . LEU A 1 241 ? 124.838 113.205 120.040 1.00 108.52 ? 241 LEU A C   1 
ATOM   1937 O  O   . LEU A 1 241 ? 123.900 112.720 120.686 1.00 115.66 ? 241 LEU A O   1 
ATOM   1938 C  CB  . LEU A 1 241 ? 124.407 114.587 117.989 1.00 109.17 ? 241 LEU A CB  1 
ATOM   1939 C  CG  . LEU A 1 241 ? 123.701 115.815 117.412 1.00 113.19 ? 241 LEU A CG  1 
ATOM   1940 C  CD1 . LEU A 1 241 ? 122.890 115.436 116.186 1.00 115.24 ? 241 LEU A CD1 1 
ATOM   1941 C  CD2 . LEU A 1 241 ? 122.816 116.476 118.457 1.00 111.24 ? 241 LEU A CD2 1 
ATOM   1942 N  N   . MET A 1 242 ? 125.882 112.480 119.734 1.00 117.59 ? 242 MET A N   1 
ATOM   1943 C  CA  . MET A 1 242 ? 126.020 111.155 120.364 1.00 118.43 ? 242 MET A CA  1 
ATOM   1944 C  C   . MET A 1 242 ? 125.943 111.330 121.874 1.00 123.54 ? 242 MET A C   1 
ATOM   1945 O  O   . MET A 1 242 ? 125.056 110.741 122.473 1.00 129.92 ? 242 MET A O   1 
ATOM   1946 C  CB  . MET A 1 242 ? 127.353 110.524 120.013 1.00 119.89 ? 242 MET A CB  1 
ATOM   1947 C  CG  . MET A 1 242 ? 127.558 110.392 118.530 1.00 122.96 ? 242 MET A CG  1 
ATOM   1948 S  SD  . MET A 1 242 ? 128.737 109.078 118.208 1.00 141.30 ? 242 MET A SD  1 
ATOM   1949 C  CE  . MET A 1 242 ? 129.890 109.338 119.553 1.00 128.39 ? 242 MET A CE  1 
ATOM   1950 N  N   . GLY A 1 243 ? 126.801 112.156 122.463 1.00 119.56 ? 243 GLY A N   1 
ATOM   1951 C  CA  . GLY A 1 243 ? 126.803 112.237 123.914 1.00 117.88 ? 243 GLY A CA  1 
ATOM   1952 C  C   . GLY A 1 243 ? 125.420 112.480 124.486 1.00 118.53 ? 243 GLY A C   1 
ATOM   1953 O  O   . GLY A 1 243 ? 125.041 111.876 125.493 1.00 123.02 ? 243 GLY A O   1 
ATOM   1954 N  N   . ILE A 1 244 ? 124.647 113.363 123.850 1.00 116.78 ? 244 ILE A N   1 
ATOM   1955 C  CA  . ILE A 1 244 ? 123.285 113.622 124.311 1.00 115.83 ? 244 ILE A CA  1 
ATOM   1956 C  C   . ILE A 1 244 ? 122.438 112.361 124.197 1.00 118.30 ? 244 ILE A C   1 
ATOM   1957 O  O   . ILE A 1 244 ? 121.689 112.011 125.120 1.00 123.58 ? 244 ILE A O   1 
ATOM   1958 C  CB  . ILE A 1 244 ? 122.671 114.798 123.526 1.00 116.54 ? 244 ILE A CB  1 
ATOM   1959 C  CG1 . ILE A 1 244 ? 122.964 116.121 124.233 1.00 118.43 ? 244 ILE A CG1 1 
ATOM   1960 C  CG2 . ILE A 1 244 ? 121.170 114.619 123.364 1.00 114.24 ? 244 ILE A CG2 1 
ATOM   1961 C  CD1 . ILE A 1 244 ? 122.472 117.335 123.479 1.00 120.37 ? 244 ILE A CD1 1 
ATOM   1962 N  N   . GLY A 1 245 ? 122.551 111.650 123.072 1.00 124.96 ? 245 GLY A N   1 
ATOM   1963 C  CA  . GLY A 1 245 ? 121.797 110.416 122.913 1.00 124.40 ? 245 GLY A CA  1 
ATOM   1964 C  C   . GLY A 1 245 ? 122.187 109.358 123.927 1.00 128.10 ? 245 GLY A C   1 
ATOM   1965 O  O   . GLY A 1 245 ? 121.324 108.684 124.499 1.00 131.29 ? 245 GLY A O   1 
ATOM   1966 N  N   . LEU A 1 246 ? 123.489 109.203 124.171 1.00 128.52 ? 246 LEU A N   1 
ATOM   1967 C  CA  . LEU A 1 246 ? 123.960 108.225 125.146 1.00 127.89 ? 246 LEU A CA  1 
ATOM   1968 C  C   . LEU A 1 246 ? 123.474 108.571 126.547 1.00 130.95 ? 246 LEU A C   1 
ATOM   1969 O  O   . LEU A 1 246 ? 123.078 107.687 127.315 1.00 132.44 ? 246 LEU A O   1 
ATOM   1970 C  CB  . LEU A 1 246 ? 125.484 108.148 125.111 1.00 126.13 ? 246 LEU A CB  1 
ATOM   1971 C  CG  . LEU A 1 246 ? 126.131 107.123 126.043 1.00 127.71 ? 246 LEU A CG  1 
ATOM   1972 C  CD1 . LEU A 1 246 ? 127.166 106.298 125.296 1.00 129.33 ? 246 LEU A CD1 1 
ATOM   1973 C  CD2 . LEU A 1 246 ? 126.750 107.811 127.251 1.00 125.30 ? 246 LEU A CD2 1 
ATOM   1974 N  N   . LEU A 1 247 ? 123.494 109.854 126.917 1.00 139.14 ? 247 LEU A N   1 
ATOM   1975 C  CA  . LEU A 1 247 ? 123.026 110.304 128.264 1.00 136.86 ? 247 LEU A CA  1 
ATOM   1976 C  C   . LEU A 1 247 ? 121.517 110.081 128.402 1.00 137.44 ? 247 LEU A C   1 
ATOM   1977 O  O   . LEU A 1 247 ? 121.100 109.657 129.476 1.00 140.96 ? 247 LEU A O   1 
ATOM   1978 C  CB  . LEU A 1 247 ? 123.398 111.774 128.504 1.00 138.23 ? 247 LEU A CB  1 
ATOM   1979 C  CG  . LEU A 1 247 ? 123.007 112.354 129.862 1.00 138.52 ? 247 LEU A CG  1 
ATOM   1980 C  CD1 . LEU A 1 247 ? 124.059 112.035 130.913 1.00 139.25 ? 247 LEU A CD1 1 
ATOM   1981 C  CD2 . LEU A 1 247 ? 122.800 113.855 129.761 1.00 136.72 ? 247 LEU A CD2 1 
ATOM   1982 N  N   . MET A 1 248 ? 120.741 110.362 127.371 1.00 140.22 ? 248 MET A N   1 
ATOM   1983 C  CA  . MET A 1 248 ? 119.301 110.017 127.442 1.00 140.50 ? 248 MET A CA  1 
ATOM   1984 C  C   . MET A 1 248 ? 119.165 108.516 127.647 1.00 143.94 ? 248 MET A C   1 
ATOM   1985 O  O   . MET A 1 248 ? 118.470 108.110 128.581 1.00 144.13 ? 248 MET A O   1 
ATOM   1986 C  CB  . MET A 1 248 ? 118.585 110.348 126.137 1.00 141.90 ? 248 MET A CB  1 
ATOM   1987 C  CG  . MET A 1 248 ? 118.528 111.820 125.835 1.00 144.03 ? 248 MET A CG  1 
ATOM   1988 S  SD  . MET A 1 248 ? 117.656 112.689 127.146 1.00 156.34 ? 248 MET A SD  1 
ATOM   1989 C  CE  . MET A 1 248 ? 116.003 112.035 126.923 1.00 143.50 ? 248 MET A CE  1 
ATOM   1990 N  N   . TRP A 1 249 ? 119.842 107.722 126.827 1.00 148.81 ? 249 TRP A N   1 
ATOM   1991 C  CA  . TRP A 1 249 ? 119.635 106.280 126.888 1.00 148.79 ? 249 TRP A CA  1 
ATOM   1992 C  C   . TRP A 1 249 ? 120.091 105.671 128.209 1.00 148.32 ? 249 TRP A C   1 
ATOM   1993 O  O   . TRP A 1 249 ? 119.520 104.663 128.637 1.00 147.88 ? 249 TRP A O   1 
ATOM   1994 C  CB  . TRP A 1 249 ? 120.359 105.609 125.718 1.00 148.88 ? 249 TRP A CB  1 
ATOM   1995 C  CG  . TRP A 1 249 ? 120.294 104.114 125.725 1.00 150.41 ? 249 TRP A CG  1 
ATOM   1996 C  CD1 . TRP A 1 249 ? 119.344 103.333 125.135 1.00 147.03 ? 249 TRP A CD1 1 
ATOM   1997 C  CD2 . TRP A 1 249 ? 121.239 103.216 126.318 1.00 152.08 ? 249 TRP A CD2 1 
ATOM   1998 N  NE1 . TRP A 1 249 ? 119.628 102.005 125.342 1.00 148.03 ? 249 TRP A NE1 1 
ATOM   1999 C  CE2 . TRP A 1 249 ? 120.790 101.907 126.065 1.00 151.14 ? 249 TRP A CE2 1 
ATOM   2000 C  CE3 . TRP A 1 249 ? 122.420 103.394 127.047 1.00 148.51 ? 249 TRP A CE3 1 
ATOM   2001 C  CZ2 . TRP A 1 249 ? 121.475 100.781 126.513 1.00 149.05 ? 249 TRP A CZ2 1 
ATOM   2002 C  CZ3 . TRP A 1 249 ? 123.101 102.276 127.491 1.00 146.85 ? 249 TRP A CZ3 1 
ATOM   2003 C  CH2 . TRP A 1 249 ? 122.626 100.986 127.222 1.00 147.89 ? 249 TRP A CH2 1 
ATOM   2004 N  N   . GLY A 1 250 ? 121.095 106.248 128.866 1.00 149.21 ? 250 GLY A N   1 
ATOM   2005 C  CA  . GLY A 1 250 ? 121.637 105.643 130.069 1.00 147.11 ? 250 GLY A CA  1 
ATOM   2006 C  C   . GLY A 1 250 ? 121.394 106.397 131.362 1.00 149.11 ? 250 GLY A C   1 
ATOM   2007 O  O   . GLY A 1 250 ? 121.987 106.064 132.394 1.00 148.31 ? 250 GLY A O   1 
ATOM   2008 N  N   . TYR A 1 251 ? 120.530 107.415 131.321 1.00 160.74 ? 251 TYR A N   1 
ATOM   2009 C  CA  . TYR A 1 251 ? 120.229 108.173 132.530 1.00 160.25 ? 251 TYR A CA  1 
ATOM   2010 C  C   . TYR A 1 251 ? 119.606 107.292 133.607 1.00 161.58 ? 251 TYR A C   1 
ATOM   2011 O  O   . TYR A 1 251 ? 119.888 107.465 134.799 1.00 160.70 ? 251 TYR A O   1 
ATOM   2012 C  CB  . TYR A 1 251 ? 119.304 109.341 132.191 1.00 159.85 ? 251 TYR A CB  1 
ATOM   2013 C  CG  . TYR A 1 251 ? 118.773 110.077 133.397 1.00 160.82 ? 251 TYR A CG  1 
ATOM   2014 C  CD1 . TYR A 1 251 ? 119.592 110.924 134.130 1.00 157.49 ? 251 TYR A CD1 1 
ATOM   2015 C  CD2 . TYR A 1 251 ? 117.455 109.927 133.804 1.00 162.00 ? 251 TYR A CD2 1 
ATOM   2016 C  CE1 . TYR A 1 251 ? 119.115 111.601 135.234 1.00 157.87 ? 251 TYR A CE1 1 
ATOM   2017 C  CE2 . TYR A 1 251 ? 116.967 110.598 134.908 1.00 161.63 ? 251 TYR A CE2 1 
ATOM   2018 C  CZ  . TYR A 1 251 ? 117.800 111.435 135.619 1.00 160.25 ? 251 TYR A CZ  1 
ATOM   2019 O  OH  . TYR A 1 251 ? 117.321 112.107 136.719 1.00 156.18 ? 251 TYR A OH  1 
ATOM   2020 N  N   . SER A 1 252 ? 118.749 106.351 133.211 1.00 161.79 ? 252 SER A N   1 
ATOM   2021 C  CA  . SER A 1 252 ? 118.083 105.475 134.168 1.00 158.69 ? 252 SER A CA  1 
ATOM   2022 C  C   . SER A 1 252 ? 119.092 104.634 134.942 1.00 159.82 ? 252 SER A C   1 
ATOM   2023 O  O   . SER A 1 252 ? 119.015 104.541 136.171 1.00 157.26 ? 252 SER A O   1 
ATOM   2024 C  CB  . SER A 1 252 ? 117.078 104.567 133.453 1.00 157.30 ? 252 SER A CB  1 
ATOM   2025 O  OG  . SER A 1 252 ? 117.700 103.839 132.409 1.00 157.15 ? 252 SER A OG  1 
ATOM   2026 N  N   . PHE A 1 253 ? 120.038 104.022 134.232 1.00 162.96 ? 253 PHE A N   1 
ATOM   2027 C  CA  . PHE A 1 253 ? 121.045 103.184 134.871 1.00 159.46 ? 253 PHE A CA  1 
ATOM   2028 C  C   . PHE A 1 253 ? 122.035 104.014 135.678 1.00 158.76 ? 253 PHE A C   1 
ATOM   2029 O  O   . PHE A 1 253 ? 122.421 103.626 136.785 1.00 156.29 ? 253 PHE A O   1 
ATOM   2030 C  CB  . PHE A 1 253 ? 121.793 102.346 133.830 1.00 160.10 ? 253 PHE A CB  1 
ATOM   2031 C  CG  . PHE A 1 253 ? 120.894 101.579 132.899 1.00 162.06 ? 253 PHE A CG  1 
ATOM   2032 C  CD1 . PHE A 1 253 ? 121.259 101.368 131.580 1.00 161.01 ? 253 PHE A CD1 1 
ATOM   2033 C  CD2 . PHE A 1 253 ? 119.691 101.054 133.346 1.00 159.81 ? 253 PHE A CD2 1 
ATOM   2034 C  CE1 . PHE A 1 253 ? 120.441 100.661 130.722 1.00 158.96 ? 253 PHE A CE1 1 
ATOM   2035 C  CE2 . PHE A 1 253 ? 118.866 100.346 132.492 1.00 157.87 ? 253 PHE A CE2 1 
ATOM   2036 C  CZ  . PHE A 1 253 ? 119.243 100.147 131.179 1.00 157.61 ? 253 PHE A CZ  1 
ATOM   2037 N  N   . LEU A 1 254 ? 122.454 105.158 135.131 1.00 165.71 ? 254 LEU A N   1 
ATOM   2038 C  CA  . LEU A 1 254 ? 123.502 105.962 135.749 1.00 166.36 ? 254 LEU A CA  1 
ATOM   2039 C  C   . LEU A 1 254 ? 123.093 106.499 137.116 1.00 165.58 ? 254 LEU A C   1 
ATOM   2040 O  O   . LEU A 1 254 ? 123.890 106.473 138.060 1.00 165.37 ? 254 LEU A O   1 
ATOM   2041 C  CB  . LEU A 1 254 ? 123.893 107.120 134.828 1.00 165.33 ? 254 LEU A CB  1 
ATOM   2042 C  CG  . LEU A 1 254 ? 125.188 107.851 135.184 1.00 163.29 ? 254 LEU A CG  1 
ATOM   2043 C  CD1 . LEU A 1 254 ? 126.391 106.958 134.928 1.00 161.96 ? 254 LEU A CD1 1 
ATOM   2044 C  CD2 . LEU A 1 254 ? 125.304 109.150 134.405 1.00 160.09 ? 254 LEU A CD2 1 
ATOM   2045 N  N   . THR A 1 255 ? 121.862 106.988 137.235 1.00 165.35 ? 255 THR A N   1 
ATOM   2046 C  CA  . THR A 1 255 ? 121.382 107.626 138.458 1.00 165.38 ? 255 THR A CA  1 
ATOM   2047 C  C   . THR A 1 255 ? 120.445 106.669 139.185 1.00 165.03 ? 255 THR A C   1 
ATOM   2048 O  O   . THR A 1 255 ? 119.374 106.329 138.672 1.00 164.56 ? 255 THR A O   1 
ATOM   2049 C  CB  . THR A 1 255 ? 120.676 108.944 138.144 1.00 165.05 ? 255 THR A CB  1 
ATOM   2050 O  OG1 . THR A 1 255 ? 121.594 109.842 137.509 1.00 164.61 ? 255 THR A OG1 1 
ATOM   2051 C  CG2 . THR A 1 255 ? 120.153 109.583 139.421 1.00 161.98 ? 255 THR A CG2 1 
ATOM   2052 N  N   . LYS A 1 256 ? 120.851 106.236 140.379 1.00 166.24 ? 256 LYS A N   1 
ATOM   2053 C  CA  . LYS A 1 256 ? 120.011 105.383 141.211 1.00 166.60 ? 256 LYS A CA  1 
ATOM   2054 C  C   . LYS A 1 256 ? 119.208 106.185 142.229 1.00 168.16 ? 256 LYS A C   1 
ATOM   2055 O  O   . LYS A 1 256 ? 118.018 105.915 142.425 1.00 167.26 ? 256 LYS A O   1 
ATOM   2056 C  CB  . LYS A 1 256 ? 120.870 104.338 141.929 1.00 165.93 ? 256 LYS A CB  1 
ATOM   2057 C  CG  . LYS A 1 256 ? 121.502 103.314 141.001 1.00 165.26 ? 256 LYS A CG  1 
ATOM   2058 C  CD  . LYS A 1 256 ? 122.358 102.325 141.773 1.00 167.25 ? 256 LYS A CD  1 
ATOM   2059 C  CE  . LYS A 1 256 ? 122.972 101.285 140.848 1.00 165.94 ? 256 LYS A CE  1 
ATOM   2060 N  NZ  . LYS A 1 256 ? 123.833 100.322 141.589 1.00 164.97 ? 256 LYS A NZ  1 
ATOM   2061 N  N   . HIS A 1 257 ? 119.842 107.167 142.877 1.00 166.80 ? 257 HIS A N   1 
ATOM   2062 C  CA  . HIS A 1 257 ? 119.177 108.083 143.805 1.00 165.79 ? 257 HIS A CA  1 
ATOM   2063 C  C   . HIS A 1 257 ? 118.511 107.328 144.957 1.00 167.58 ? 257 HIS A C   1 
ATOM   2064 O  O   . HIS A 1 257 ? 117.288 107.318 145.112 1.00 166.70 ? 257 HIS A O   1 
ATOM   2065 C  CB  . HIS A 1 257 ? 118.167 108.969 143.066 1.00 166.25 ? 257 HIS A CB  1 
ATOM   2066 C  CG  . HIS A 1 257 ? 117.684 110.133 143.872 1.00 165.61 ? 257 HIS A CG  1 
ATOM   2067 N  ND1 . HIS A 1 257 ? 118.433 111.277 144.053 1.00 165.89 ? 257 HIS A ND1 1 
ATOM   2068 C  CD2 . HIS A 1 257 ? 116.526 110.333 144.545 1.00 163.82 ? 257 HIS A CD2 1 
ATOM   2069 C  CE1 . HIS A 1 257 ? 117.757 112.129 144.802 1.00 164.50 ? 257 HIS A CE1 1 
ATOM   2070 N  NE2 . HIS A 1 257 ? 116.596 111.580 145.113 1.00 162.97 ? 257 HIS A NE2 1 
ATOM   2071 N  N   . GLU A 1 258 ? 119.346 106.683 145.770 1.00 167.30 ? 258 GLU A N   1 
ATOM   2072 C  CA  . GLU A 1 258 ? 118.887 105.992 146.974 1.00 167.56 ? 258 GLU A CA  1 
ATOM   2073 C  C   . GLU A 1 258 ? 118.661 107.033 148.063 1.00 168.84 ? 258 GLU A C   1 
ATOM   2074 O  O   . GLU A 1 258 ? 119.554 107.351 148.850 1.00 167.48 ? 258 GLU A O   1 
ATOM   2075 C  CB  . GLU A 1 258 ? 119.894 104.933 147.402 1.00 164.93 ? 258 GLU A CB  1 
ATOM   2076 C  CG  . GLU A 1 258 ? 120.464 104.128 146.245 1.00 164.89 ? 258 GLU A CG  1 
ATOM   2077 C  CD  . GLU A 1 258 ? 121.941 103.828 146.410 1.00 165.79 ? 258 GLU A CD  1 
ATOM   2078 O  OE1 . GLU A 1 258 ? 122.534 104.283 147.411 1.00 164.70 ? 258 GLU A OE1 1 
ATOM   2079 O  OE2 . GLU A 1 258 ? 122.508 103.136 145.539 1.00 164.30 ? 258 GLU A OE2 1 
ATOM   2080 N  N   . GLU A 1 259 ? 117.443 107.571 148.106 1.00 167.13 ? 259 GLU A N   1 
ATOM   2081 C  CA  . GLU A 1 259 ? 117.127 108.663 149.016 1.00 164.96 ? 259 GLU A CA  1 
ATOM   2082 C  C   . GLU A 1 259 ? 117.089 108.178 150.462 1.00 165.36 ? 259 GLU A C   1 
ATOM   2083 O  O   . GLU A 1 259 ? 116.780 107.014 150.733 1.00 163.33 ? 259 GLU A O   1 
ATOM   2084 C  CB  . GLU A 1 259 ? 115.786 109.294 148.638 1.00 161.07 ? 259 GLU A CB  1 
ATOM   2085 N  N   . VAL A 1 260 ? 117.409 109.078 151.388 1.00 162.96 ? 260 VAL A N   1 
ATOM   2086 C  CA  . VAL A 1 260 ? 117.397 108.770 152.810 1.00 162.05 ? 260 VAL A CA  1 
ATOM   2087 C  C   . VAL A 1 260 ? 116.158 109.386 153.448 1.00 162.11 ? 260 VAL A C   1 
ATOM   2088 O  O   . VAL A 1 260 ? 115.510 110.272 152.886 1.00 160.89 ? 260 VAL A O   1 
ATOM   2089 C  CB  . VAL A 1 260 ? 118.681 109.268 153.505 1.00 161.25 ? 260 VAL A CB  1 
ATOM   2090 C  CG1 . VAL A 1 260 ? 118.555 110.737 153.879 1.00 161.42 ? 260 VAL A CG1 1 
ATOM   2091 C  CG2 . VAL A 1 260 ? 119.002 108.417 154.727 1.00 159.80 ? 260 VAL A CG2 1 
ATOM   2092 N  N   . GLU A 1 261 ? 115.820 108.901 154.640 1.00 168.96 ? 261 GLU A N   1 
ATOM   2093 C  CA  . GLU A 1 261 ? 114.739 109.498 155.410 1.00 169.49 ? 261 GLU A CA  1 
ATOM   2094 C  C   . GLU A 1 261 ? 115.139 110.883 155.903 1.00 171.88 ? 261 GLU A C   1 
ATOM   2095 O  O   . GLU A 1 261 ? 116.269 111.109 156.349 1.00 171.03 ? 261 GLU A O   1 
ATOM   2096 C  CB  . GLU A 1 261 ? 114.370 108.605 156.595 1.00 165.31 ? 261 GLU A CB  1 
ATOM   2097 N  N   . VAL A 1 262 ? 114.200 111.815 155.822 1.00 171.42 ? 262 VAL A N   1 
ATOM   2098 C  CA  . VAL A 1 262 ? 114.462 113.197 156.227 1.00 170.14 ? 262 VAL A CA  1 
ATOM   2099 C  C   . VAL A 1 262 ? 114.588 113.250 157.749 1.00 168.86 ? 262 VAL A C   1 
ATOM   2100 O  O   . VAL A 1 262 ? 113.757 112.652 158.451 1.00 164.75 ? 262 VAL A O   1 
ATOM   2101 C  CB  . VAL A 1 262 ? 113.350 114.121 155.728 1.00 167.84 ? 262 VAL A CB  1 
ATOM   2102 C  CG1 . VAL A 1 262 ? 111.978 113.551 156.063 1.00 165.93 ? 262 VAL A CG1 1 
ATOM   2103 C  CG2 . VAL A 1 262 ? 113.507 115.522 156.306 1.00 166.06 ? 262 VAL A CG2 1 
ATOM   2104 N  N   . PRO A 1 263 ? 115.609 113.921 158.292 1.00 168.12 ? 263 PRO A N   1 
ATOM   2105 C  CA  . PRO A 1 263 ? 115.717 114.033 159.750 1.00 166.87 ? 263 PRO A CA  1 
ATOM   2106 C  C   . PRO A 1 263 ? 114.855 115.160 160.300 1.00 168.34 ? 263 PRO A C   1 
ATOM   2107 O  O   . PRO A 1 263 ? 114.170 115.853 159.540 1.00 167.56 ? 263 PRO A O   1 
ATOM   2108 C  CB  . PRO A 1 263 ? 117.209 114.298 159.976 1.00 164.16 ? 263 PRO A CB  1 
ATOM   2109 C  CG  . PRO A 1 263 ? 117.724 114.849 158.674 1.00 164.16 ? 263 PRO A CG  1 
ATOM   2110 C  CD  . PRO A 1 263 ? 116.693 114.635 157.596 1.00 165.33 ? 263 PRO A CD  1 
ATOM   2111 N  N   . THR A 1 264 ? 114.881 115.349 161.617 1.00 174.96 ? 264 THR A N   1 
ATOM   2112 C  CA  . THR A 1 264 ? 114.060 116.353 162.281 1.00 174.22 ? 264 THR A CA  1 
ATOM   2113 C  C   . THR A 1 264 ? 114.875 117.499 162.862 1.00 173.70 ? 264 THR A C   1 
ATOM   2114 O  O   . THR A 1 264 ? 114.480 118.663 162.742 1.00 171.10 ? 264 THR A O   1 
ATOM   2115 C  CB  . THR A 1 264 ? 113.223 115.703 163.394 1.00 172.79 ? 264 THR A CB  1 
ATOM   2116 O  OG1 . THR A 1 264 ? 114.093 115.077 164.345 1.00 172.26 ? 264 THR A OG1 1 
ATOM   2117 C  CG2 . THR A 1 264 ? 112.281 114.660 162.812 1.00 171.29 ? 264 THR A CG2 1 
ATOM   2118 N  N   . GLU A 1 265 ? 116.011 117.201 163.490 1.00 176.94 ? 265 GLU A N   1 
ATOM   2119 C  CA  . GLU A 1 265 ? 116.817 118.232 164.129 1.00 175.28 ? 265 GLU A CA  1 
ATOM   2120 C  C   . GLU A 1 265 ? 117.682 118.967 163.112 1.00 176.89 ? 265 GLU A C   1 
ATOM   2121 O  O   . GLU A 1 265 ? 117.535 118.768 161.901 1.00 177.13 ? 265 GLU A O   1 
ATOM   2122 C  CB  . GLU A 1 265 ? 117.694 117.622 165.224 1.00 172.35 ? 265 GLU A CB  1 
ATOM   2123 N  N   . ASP A 1 266 ? 118.584 119.816 163.597 1.00 173.06 ? 266 ASP A N   1 
ATOM   2124 C  CA  . ASP A 1 266 ? 119.483 120.582 162.744 1.00 171.74 ? 266 ASP A CA  1 
ATOM   2125 C  C   . ASP A 1 266 ? 120.924 120.352 163.184 1.00 174.20 ? 266 ASP A C   1 
ATOM   2126 O  O   . ASP A 1 266 ? 121.441 121.098 164.026 1.00 174.46 ? 266 ASP A O   1 
ATOM   2127 C  CB  . ASP A 1 266 ? 119.135 122.071 162.792 1.00 167.81 ? 266 ASP A CB  1 
ATOM   2128 N  N   . PRO A 1 267 ? 121.595 119.324 162.651 1.00 171.57 ? 267 PRO A N   1 
ATOM   2129 C  CA  . PRO A 1 267 ? 122.967 119.026 163.088 1.00 169.98 ? 267 PRO A CA  1 
ATOM   2130 C  C   . PRO A 1 267 ? 123.935 120.178 162.873 1.00 169.31 ? 267 PRO A C   1 
ATOM   2131 O  O   . PRO A 1 267 ? 124.836 120.396 163.686 1.00 168.16 ? 267 PRO A O   1 
ATOM   2132 C  CB  . PRO A 1 267 ? 123.358 117.843 162.198 1.00 30.00  ? 267 PRO A CB  1 
ATOM   2133 C  CG  . PRO A 1 267 ? 122.604 118.057 160.931 1.00 30.00  ? 267 PRO A CG  1 
ATOM   2134 C  CD  . PRO A 1 267 ? 121.831 119.321 161.139 1.00 30.00  ? 267 PRO A CD  1 
ATOM   2135 N  N   . SER A 1 269 ? 122.461 122.568 161.941 1.00 159.27 ? 269 SER A N   1 
ATOM   2136 C  CA  . SER A 1 269 ? 122.527 123.958 162.465 1.00 154.66 ? 269 SER A CA  1 
ATOM   2137 C  C   . SER A 1 269 ? 123.050 123.957 163.904 1.00 156.77 ? 269 SER A C   1 
ATOM   2138 O  O   . SER A 1 269 ? 123.288 125.058 164.435 1.00 154.81 ? 269 SER A O   1 
ATOM   2139 C  CB  . SER A 1 269 ? 121.188 124.641 162.367 1.00 30.00  ? 269 SER A CB  1 
ATOM   2140 O  OG  . SER A 1 269 ? 121.286 125.998 162.776 1.00 30.00  ? 269 SER A OG  1 
ATOM   2141 N  N   . LYS A 1 270 ? 123.233 122.782 164.510 1.00 164.69 ? 270 LYS A N   1 
ATOM   2142 C  CA  . LYS A 1 270 ? 123.835 122.733 165.869 1.00 163.55 ? 270 LYS A CA  1 
ATOM   2143 C  C   . LYS A 1 270 ? 125.320 123.083 165.738 1.00 165.72 ? 270 LYS A C   1 
ATOM   2144 O  O   . LYS A 1 270 ? 126.148 122.153 165.791 1.00 165.17 ? 270 LYS A O   1 
ATOM   2145 C  CB  . LYS A 1 270 ? 123.632 121.350 166.496 1.00 159.93 ? 270 LYS A CB  1 
ATOM   2146 N  N   . VAL A 1 271 ? 125.642 124.368 165.563 1.00 158.08 ? 271 VAL A N   1 
ATOM   2147 C  CA  . VAL A 1 271 ? 127.065 124.761 165.326 1.00 155.61 ? 271 VAL A CA  1 
ATOM   2148 C  C   . VAL A 1 271 ? 127.493 125.836 166.330 1.00 154.06 ? 271 VAL A C   1 
ATOM   2149 O  O   . VAL A 1 271 ? 127.249 127.031 166.063 1.00 149.80 ? 271 VAL A O   1 
ATOM   2150 C  CB  . VAL A 1 271 ? 127.290 125.208 163.867 1.00 155.26 ? 271 VAL A CB  1 
ATOM   2151 C  CG1 . VAL A 1 271 ? 126.178 126.115 163.360 1.00 154.39 ? 271 VAL A CG1 1 
ATOM   2152 C  CG2 . VAL A 1 271 ? 128.655 125.850 163.663 1.00 155.52 ? 271 VAL A CG2 1 
ATOM   2153 N  N   . GLN A 1 272 ? 128.089 125.429 167.457 1.00 139.06 ? 272 GLN A N   1 
ATOM   2154 C  CA  . GLN A 1 272 ? 128.636 126.410 168.409 1.00 135.55 ? 272 GLN A CA  1 
ATOM   2155 C  C   . GLN A 1 272 ? 129.698 127.086 167.558 1.00 135.09 ? 272 GLN A C   1 
ATOM   2156 O  O   . GLN A 1 272 ? 130.573 126.380 167.082 1.00 136.54 ? 272 GLN A O   1 
ATOM   2157 C  CB  . GLN A 1 272 ? 129.144 125.747 169.678 1.00 133.79 ? 272 GLN A CB  1 
ATOM   2158 C  CG  . GLN A 1 272 ? 128.037 125.131 170.514 1.00 136.67 ? 272 GLN A CG  1 
ATOM   2159 C  CD  . GLN A 1 272 ? 128.567 124.416 171.732 1.00 139.36 ? 272 GLN A CD  1 
ATOM   2160 O  OE1 . GLN A 1 272 ? 129.712 123.971 171.762 1.00 138.99 ? 272 GLN A OE1 1 
ATOM   2161 N  NE2 . GLN A 1 272 ? 127.733 124.293 172.750 1.00 139.36 ? 272 GLN A NE2 1 
ATOM   2162 N  N   . LEU A 1 273 ? 129.615 128.385 167.364 1.00 110.12 ? 273 LEU A N   1 
ATOM   2163 C  CA  . LEU A 1 273 ? 130.482 129.101 166.438 1.00 111.88 ? 273 LEU A CA  1 
ATOM   2164 C  C   . LEU A 1 273 ? 131.856 129.326 167.056 1.00 114.41 ? 273 LEU A C   1 
ATOM   2165 O  O   . LEU A 1 273 ? 131.966 129.707 168.225 1.00 113.90 ? 273 LEU A O   1 
ATOM   2166 C  CB  . LEU A 1 273 ? 129.854 130.439 166.051 1.00 113.51 ? 273 LEU A CB  1 
ATOM   2167 C  CG  . LEU A 1 273 ? 128.628 130.392 165.139 1.00 111.20 ? 273 LEU A CG  1 
ATOM   2168 C  CD1 . LEU A 1 273 ? 128.010 131.772 165.013 1.00 111.75 ? 273 LEU A CD1 1 
ATOM   2169 C  CD2 . LEU A 1 273 ? 128.994 129.842 163.773 1.00 109.92 ? 273 LEU A CD2 1 
ATOM   2170 N  N   . THR A 1 274 ? 132.887 129.088 166.260 1.00 104.97 ? 274 THR A N   1 
ATOM   2171 C  CA  . THR A 1 274 ? 134.296 129.272 166.692 1.00 101.82 ? 274 THR A CA  1 
ATOM   2172 C  C   . THR A 1 274 ? 134.637 130.757 166.487 1.00 105.00 ? 274 THR A C   1 
ATOM   2173 O  O   . THR A 1 274 ? 133.949 131.394 165.720 1.00 104.09 ? 274 THR A O   1 
ATOM   2174 C  CB  . THR A 1 274 ? 135.209 128.206 166.043 1.00 102.58 ? 274 THR A CB  1 
ATOM   2175 O  OG1 . THR A 1 274 ? 135.558 128.677 164.741 1.00 103.83 ? 274 THR A OG1 1 
ATOM   2176 C  CG2 . THR A 1 274 ? 134.587 126.835 165.952 1.00 103.54 ? 274 THR A CG2 1 
ATOM   2177 N  N   . PRO A 1 275 ? 135.600 131.347 167.224 1.00 100.53 ? 275 PRO A N   1 
ATOM   2178 C  CA  . PRO A 1 275 ? 135.999 132.749 167.002 1.00 97.55  ? 275 PRO A CA  1 
ATOM   2179 C  C   . PRO A 1 275 ? 136.373 133.054 165.563 1.00 96.78  ? 275 PRO A C   1 
ATOM   2180 O  O   . PRO A 1 275 ? 136.115 134.164 165.083 1.00 95.58  ? 275 PRO A O   1 
ATOM   2181 C  CB  . PRO A 1 275 ? 137.192 132.920 167.951 1.00 92.80  ? 275 PRO A CB  1 
ATOM   2182 C  CG  . PRO A 1 275 ? 136.969 131.918 169.017 1.00 93.78  ? 275 PRO A CG  1 
ATOM   2183 C  CD  . PRO A 1 275 ? 136.316 130.742 168.359 1.00 95.56  ? 275 PRO A CD  1 
ATOM   2184 N  N   . SER A 1 276 ? 136.989 132.101 164.863 1.00 92.78  ? 276 SER A N   1 
ATOM   2185 C  CA  . SER A 1 276 ? 137.322 132.315 163.458 1.00 91.29  ? 276 SER A CA  1 
ATOM   2186 C  C   . SER A 1 276 ? 136.069 132.414 162.598 1.00 95.06  ? 276 SER A C   1 
ATOM   2187 O  O   . SER A 1 276 ? 136.019 133.212 161.655 1.00 100.92 ? 276 SER A O   1 
ATOM   2188 C  CB  . SER A 1 276 ? 138.229 131.191 162.959 1.00 89.76  ? 276 SER A CB  1 
ATOM   2189 O  OG  . SER A 1 276 ? 138.148 131.050 161.553 1.00 97.09  ? 276 SER A OG  1 
ATOM   2190 N  N   . GLN A 1 277 ? 135.053 131.601 162.897 1.00 91.78  ? 277 GLN A N   1 
ATOM   2191 C  CA  . GLN A 1 277 ? 133.809 131.661 162.137 1.00 91.93  ? 277 GLN A CA  1 
ATOM   2192 C  C   . GLN A 1 277 ? 133.100 132.994 162.337 1.00 97.77  ? 277 GLN A C   1 
ATOM   2193 O  O   . GLN A 1 277 ? 132.536 133.555 161.392 1.00 103.97 ? 277 GLN A O   1 
ATOM   2194 C  CB  . GLN A 1 277 ? 132.890 130.505 162.528 1.00 91.96  ? 277 GLN A CB  1 
ATOM   2195 C  CG  . GLN A 1 277 ? 133.011 129.288 161.631 1.00 91.94  ? 277 GLN A CG  1 
ATOM   2196 C  CD  . GLN A 1 277 ? 132.496 128.026 162.288 1.00 95.63  ? 277 GLN A CD  1 
ATOM   2197 O  OE1 . GLN A 1 277 ? 132.414 127.938 163.510 1.00 100.47 ? 277 GLN A OE1 1 
ATOM   2198 N  NE2 . GLN A 1 277 ? 132.139 127.041 161.474 1.00 94.71  ? 277 GLN A NE2 1 
ATOM   2199 N  N   . LYS A 1 278 ? 133.120 133.517 163.563 1.00 90.28  ? 278 LYS A N   1 
ATOM   2200 C  CA  . LYS A 1 278 ? 132.442 134.771 163.867 1.00 87.44  ? 278 LYS A CA  1 
ATOM   2201 C  C   . LYS A 1 278 ? 133.083 135.972 163.189 1.00 89.51  ? 278 LYS A C   1 
ATOM   2202 O  O   . LYS A 1 278 ? 132.483 137.051 163.186 1.00 90.99  ? 278 LYS A O   1 
ATOM   2203 C  CB  . LYS A 1 278 ? 132.408 134.991 165.378 1.00 84.15  ? 278 LYS A CB  1 
ATOM   2204 C  CG  . LYS A 1 278 ? 131.360 134.161 166.096 1.00 88.49  ? 278 LYS A CG  1 
ATOM   2205 C  CD  . LYS A 1 278 ? 130.923 134.819 167.390 1.00 89.91  ? 278 LYS A CD  1 
ATOM   2206 C  CE  . LYS A 1 278 ? 131.860 134.471 168.530 1.00 91.73  ? 278 LYS A CE  1 
ATOM   2207 N  NZ  . LYS A 1 278 ? 131.521 133.158 169.140 1.00 93.12  ? 278 LYS A NZ  1 
ATOM   2208 N  N   . ALA A 1 279 ? 134.276 135.818 162.613 1.00 90.28  ? 279 ALA A N   1 
ATOM   2209 C  CA  . ALA A 1 279 ? 134.981 136.907 161.950 1.00 89.38  ? 279 ALA A CA  1 
ATOM   2210 C  C   . ALA A 1 279 ? 134.732 136.933 160.446 1.00 87.83  ? 279 ALA A C   1 
ATOM   2211 O  O   . ALA A 1 279 ? 135.488 137.565 159.705 1.00 90.77  ? 279 ALA A O   1 
ATOM   2212 C  CB  . ALA A 1 279 ? 136.480 136.816 162.238 1.00 88.89  ? 279 ALA A CB  1 
ATOM   2213 N  N   . LEU A 1 280 ? 133.680 136.264 159.982 1.00 79.48  ? 280 LEU A N   1 
ATOM   2214 C  CA  . LEU A 1 280 ? 133.359 136.208 158.562 1.00 82.05  ? 280 LEU A CA  1 
ATOM   2215 C  C   . LEU A 1 280 ? 132.221 137.140 158.169 1.00 82.52  ? 280 LEU A C   1 
ATOM   2216 O  O   . LEU A 1 280 ? 131.873 137.211 156.984 1.00 87.32  ? 280 LEU A O   1 
ATOM   2217 C  CB  . LEU A 1 280 ? 133.021 134.771 158.158 1.00 82.11  ? 280 LEU A CB  1 
ATOM   2218 C  CG  . LEU A 1 280 ? 134.169 133.770 158.313 1.00 76.32  ? 280 LEU A CG  1 
ATOM   2219 C  CD1 . LEU A 1 280 ? 133.821 132.468 157.639 1.00 81.05  ? 280 LEU A CD1 1 
ATOM   2220 C  CD2 . LEU A 1 280 ? 135.463 134.332 157.748 1.00 81.47  ? 280 LEU A CD2 1 
ATOM   2221 N  N   . GLY A 1 281 ? 131.635 137.860 159.128 1.00 83.14  ? 281 GLY A N   1 
ATOM   2222 C  CA  . GLY A 1 281 ? 130.656 138.870 158.776 1.00 88.50  ? 281 GLY A CA  1 
ATOM   2223 C  C   . GLY A 1 281 ? 131.247 139.977 157.930 1.00 91.97  ? 281 GLY A C   1 
ATOM   2224 O  O   . GLY A 1 281 ? 130.600 140.470 157.001 1.00 101.59 ? 281 GLY A O   1 
ATOM   2225 N  N   . LYS A 1 282 ? 132.484 140.377 158.229 1.00 84.76  ? 282 LYS A N   1 
ATOM   2226 C  CA  . LYS A 1 282 ? 133.161 141.359 157.392 1.00 88.63  ? 282 LYS A CA  1 
ATOM   2227 C  C   . LYS A 1 282 ? 133.422 140.805 155.996 1.00 91.38  ? 282 LYS A C   1 
ATOM   2228 O  O   . LYS A 1 282 ? 133.358 141.547 155.012 1.00 95.63  ? 282 LYS A O   1 
ATOM   2229 C  CB  . LYS A 1 282 ? 134.459 141.820 158.058 1.00 85.81  ? 282 LYS A CB  1 
ATOM   2230 C  CG  . LYS A 1 282 ? 135.513 140.743 158.238 1.00 86.73  ? 282 LYS A CG  1 
ATOM   2231 C  CD  . LYS A 1 282 ? 136.822 141.338 158.730 1.00 88.21  ? 282 LYS A CD  1 
ATOM   2232 C  CE  . LYS A 1 282 ? 137.448 140.494 159.825 1.00 90.78  ? 282 LYS A CE  1 
ATOM   2233 N  NZ  . LYS A 1 282 ? 136.734 140.645 161.121 1.00 93.84  ? 282 LYS A NZ  1 
ATOM   2234 N  N   . TYR A 1 283 ? 133.697 139.503 155.885 1.00 84.86  ? 283 TYR A N   1 
ATOM   2235 C  CA  . TYR A 1 283 ? 133.840 138.888 154.568 1.00 80.09  ? 283 TYR A CA  1 
ATOM   2236 C  C   . TYR A 1 283 ? 132.534 138.950 153.786 1.00 80.64  ? 283 TYR A C   1 
ATOM   2237 O  O   . TYR A 1 283 ? 132.529 139.260 152.588 1.00 89.52  ? 283 TYR A O   1 
ATOM   2238 C  CB  . TYR A 1 283 ? 134.298 137.437 154.709 1.00 78.58  ? 283 TYR A CB  1 
ATOM   2239 C  CG  . TYR A 1 283 ? 135.774 137.262 154.965 1.00 84.19  ? 283 TYR A CG  1 
ATOM   2240 C  CD1 . TYR A 1 283 ? 136.335 137.617 156.182 1.00 83.71  ? 283 TYR A CD1 1 
ATOM   2241 C  CD2 . TYR A 1 283 ? 136.606 136.731 153.991 1.00 82.73  ? 283 TYR A CD2 1 
ATOM   2242 C  CE1 . TYR A 1 283 ? 137.682 137.452 156.420 1.00 80.18  ? 283 TYR A CE1 1 
ATOM   2243 C  CE2 . TYR A 1 283 ? 137.955 136.563 154.220 1.00 81.72  ? 283 TYR A CE2 1 
ATOM   2244 C  CZ  . TYR A 1 283 ? 138.487 136.926 155.438 1.00 84.65  ? 283 TYR A CZ  1 
ATOM   2245 O  OH  . TYR A 1 283 ? 139.830 136.761 155.672 1.00 93.55  ? 283 TYR A OH  1 
ATOM   2246 N  N   . VAL A 1 284 ? 131.417 138.651 154.450 1.00 73.67  ? 284 VAL A N   1 
ATOM   2247 C  CA  . VAL A 1 284 ? 130.113 138.700 153.788 1.00 75.55  ? 284 VAL A CA  1 
ATOM   2248 C  C   . VAL A 1 284 ? 129.809 140.120 153.321 1.00 76.70  ? 284 VAL A C   1 
ATOM   2249 O  O   . VAL A 1 284 ? 129.354 140.347 152.189 1.00 82.23  ? 284 VAL A O   1 
ATOM   2250 C  CB  . VAL A 1 284 ? 129.016 138.169 154.728 1.00 75.80  ? 284 VAL A CB  1 
ATOM   2251 C  CG1 . VAL A 1 284 ? 127.641 138.380 154.121 1.00 76.56  ? 284 VAL A CG1 1 
ATOM   2252 C  CG2 . VAL A 1 284 ? 129.249 136.702 155.039 1.00 76.92  ? 284 VAL A CG2 1 
ATOM   2253 N  N   . PHE A 1 285 ? 130.059 141.100 154.195 1.00 72.91  ? 285 PHE A N   1 
ATOM   2254 C  CA  . PHE A 1 285 ? 129.813 142.489 153.832 1.00 73.07  ? 285 PHE A CA  1 
ATOM   2255 C  C   . PHE A 1 285 ? 130.706 142.924 152.678 1.00 81.39  ? 285 PHE A C   1 
ATOM   2256 O  O   . PHE A 1 285 ? 130.259 143.643 151.779 1.00 88.31  ? 285 PHE A O   1 
ATOM   2257 C  CB  . PHE A 1 285 ? 130.023 143.407 155.034 1.00 74.16  ? 285 PHE A CB  1 
ATOM   2258 C  CG  . PHE A 1 285 ? 129.866 144.861 154.706 1.00 81.69  ? 285 PHE A CG  1 
ATOM   2259 C  CD1 . PHE A 1 285 ? 128.614 145.395 154.455 1.00 79.67  ? 285 PHE A CD1 1 
ATOM   2260 C  CD2 . PHE A 1 285 ? 130.969 145.691 154.625 1.00 88.15  ? 285 PHE A CD2 1 
ATOM   2261 C  CE1 . PHE A 1 285 ? 128.465 146.729 154.144 1.00 86.23  ? 285 PHE A CE1 1 
ATOM   2262 C  CE2 . PHE A 1 285 ? 130.826 147.027 154.314 1.00 91.92  ? 285 PHE A CE2 1 
ATOM   2263 C  CZ  . PHE A 1 285 ? 129.572 147.546 154.075 1.00 90.17  ? 285 PHE A CZ  1 
ATOM   2264 N  N   . LEU A 1 286 ? 131.975 142.515 152.695 1.00 80.78  ? 286 LEU A N   1 
ATOM   2265 C  CA  . LEU A 1 286 ? 132.873 142.855 151.599 1.00 80.36  ? 286 LEU A CA  1 
ATOM   2266 C  C   . LEU A 1 286 ? 132.384 142.258 150.291 1.00 79.91  ? 286 LEU A C   1 
ATOM   2267 O  O   . LEU A 1 286 ? 132.408 142.923 149.249 1.00 89.33  ? 286 LEU A O   1 
ATOM   2268 C  CB  . LEU A 1 286 ? 134.291 142.375 151.914 1.00 72.72  ? 286 LEU A CB  1 
ATOM   2269 C  CG  . LEU A 1 286 ? 135.310 142.420 150.776 1.00 74.42  ? 286 LEU A CG  1 
ATOM   2270 C  CD1 . LEU A 1 286 ? 135.609 143.854 150.381 1.00 83.24  ? 286 LEU A CD1 1 
ATOM   2271 C  CD2 . LEU A 1 286 ? 136.585 141.699 151.173 1.00 77.87  ? 286 LEU A CD2 1 
ATOM   2272 N  N   . THR A 1 287 ? 131.915 141.008 150.328 1.00 75.38  ? 287 THR A N   1 
ATOM   2273 C  CA  . THR A 1 287 ? 131.389 140.370 149.127 1.00 77.48  ? 287 THR A CA  1 
ATOM   2274 C  C   . THR A 1 287 ? 130.216 141.159 148.553 1.00 78.45  ? 287 THR A C   1 
ATOM   2275 O  O   . THR A 1 287 ? 130.198 141.493 147.362 1.00 86.70  ? 287 THR A O   1 
ATOM   2276 C  CB  . THR A 1 287 ? 130.971 138.933 149.443 1.00 80.29  ? 287 THR A CB  1 
ATOM   2277 O  OG1 . THR A 1 287 ? 132.120 138.177 149.841 1.00 89.78  ? 287 THR A OG1 1 
ATOM   2278 C  CG2 . THR A 1 287 ? 130.345 138.279 148.225 1.00 71.30  ? 287 THR A CG2 1 
ATOM   2279 N  N   . VAL A 1 288 ? 129.193 141.394 149.323 1.00 68.48  ? 288 VAL A N   1 
ATOM   2280 C  CA  . VAL A 1 288 ? 128.011 142.145 148.805 1.00 71.05  ? 288 VAL A CA  1 
ATOM   2281 C  C   . VAL A 1 288 ? 128.341 143.604 148.459 1.00 75.91  ? 288 VAL A C   1 
ATOM   2282 O  O   . VAL A 1 288 ? 127.735 144.073 147.531 1.00 80.18  ? 288 VAL A O   1 
ATOM   2283 C  CB  . VAL A 1 288 ? 126.760 142.010 149.723 1.00 72.03  ? 288 VAL A CB  1 
ATOM   2284 C  CG1 . VAL A 1 288 ? 126.221 140.589 149.757 1.00 70.57  ? 288 VAL A CG1 1 
ATOM   2285 C  CG2 . VAL A 1 288 ? 126.919 142.631 151.103 1.00 80.81  ? 288 VAL A CG2 1 
ATOM   2286 N  N   . ALA A 1 289 ? 129.225 144.292 149.168 1.00 59.17  ? 289 ALA A N   1 
ATOM   2287 C  CA  . ALA A 1 289 ? 129.592 145.650 148.783 1.00 57.86  ? 289 ALA A CA  1 
ATOM   2288 C  C   . ALA A 1 289 ? 130.355 145.662 147.464 1.00 62.06  ? 289 ALA A C   1 
ATOM   2289 O  O   . ALA A 1 289 ? 130.120 146.531 146.615 1.00 71.08  ? 289 ALA A O   1 
ATOM   2290 C  CB  . ALA A 1 289 ? 130.420 146.303 149.889 1.00 62.77  ? 289 ALA A CB  1 
ATOM   2291 N  N   . LEU A 1 290 ? 131.267 144.707 147.271 1.00 66.54  ? 290 LEU A N   1 
ATOM   2292 C  CA  . LEU A 1 290 ? 131.967 144.600 145.998 1.00 64.67  ? 290 LEU A CA  1 
ATOM   2293 C  C   . LEU A 1 290 ? 131.003 144.262 144.872 1.00 75.06  ? 290 LEU A C   1 
ATOM   2294 O  O   . LEU A 1 290 ? 131.161 144.753 143.751 1.00 87.38  ? 290 LEU A O   1 
ATOM   2295 C  CB  . LEU A 1 290 ? 133.072 143.552 146.094 1.00 62.59  ? 290 LEU A CB  1 
ATOM   2296 C  CG  . LEU A 1 290 ? 134.504 144.063 146.212 1.00 69.11  ? 290 LEU A CG  1 
ATOM   2297 C  CD1 . LEU A 1 290 ? 135.479 142.900 146.230 1.00 76.99  ? 290 LEU A CD1 1 
ATOM   2298 C  CD2 . LEU A 1 290 ? 134.825 145.016 145.076 1.00 73.95  ? 290 LEU A CD2 1 
ATOM   2299 N  N   . PHE A 1 291 ? 130.000 143.427 145.148 1.00 69.29  ? 291 PHE A N   1 
ATOM   2300 C  CA  . PHE A 1 291 ? 128.991 143.118 144.141 1.00 63.19  ? 291 PHE A CA  1 
ATOM   2301 C  C   . PHE A 1 291 ? 128.240 144.377 143.712 1.00 68.25  ? 291 PHE A C   1 
ATOM   2302 O  O   . PHE A 1 291 ? 128.047 144.625 142.513 1.00 73.63  ? 291 PHE A O   1 
ATOM   2303 C  CB  . PHE A 1 291 ? 128.032 142.062 144.695 1.00 57.46  ? 291 PHE A CB  1 
ATOM   2304 C  CG  . PHE A 1 291 ? 126.863 141.753 143.805 1.00 59.56  ? 291 PHE A CG  1 
ATOM   2305 C  CD1 . PHE A 1 291 ? 127.023 141.625 142.438 1.00 69.39  ? 291 PHE A CD1 1 
ATOM   2306 C  CD2 . PHE A 1 291 ? 125.605 141.566 144.346 1.00 63.95  ? 291 PHE A CD2 1 
ATOM   2307 C  CE1 . PHE A 1 291 ? 125.946 141.330 141.627 1.00 72.58  ? 291 PHE A CE1 1 
ATOM   2308 C  CE2 . PHE A 1 291 ? 124.526 141.270 143.540 1.00 66.32  ? 291 PHE A CE2 1 
ATOM   2309 C  CZ  . PHE A 1 291 ? 124.697 141.155 142.179 1.00 70.20  ? 291 PHE A CZ  1 
ATOM   2310 N  N   . VAL A 1 292 ? 127.830 145.194 144.683 1.00 65.97  ? 292 VAL A N   1 
ATOM   2311 C  CA  . VAL A 1 292 ? 127.101 146.419 144.363 1.00 57.36  ? 292 VAL A CA  1 
ATOM   2312 C  C   . VAL A 1 292 ? 127.987 147.382 143.579 1.00 64.25  ? 292 VAL A C   1 
ATOM   2313 O  O   . VAL A 1 292 ? 127.554 147.985 142.588 1.00 76.68  ? 292 VAL A O   1 
ATOM   2314 C  CB  . VAL A 1 292 ? 126.553 147.070 145.648 1.00 56.92  ? 292 VAL A CB  1 
ATOM   2315 C  CG1 . VAL A 1 292 ? 126.353 148.564 145.450 1.00 56.24  ? 292 VAL A CG1 1 
ATOM   2316 C  CG2 . VAL A 1 292 ? 125.251 146.415 146.046 1.00 68.59  ? 292 VAL A CG2 1 
ATOM   2317 N  N   . VAL A 1 293 ? 129.244 147.534 144.005 1.00 62.61  ? 293 VAL A N   1 
ATOM   2318 C  CA  . VAL A 1 293 ? 130.161 148.434 143.314 1.00 58.22  ? 293 VAL A CA  1 
ATOM   2319 C  C   . VAL A 1 293 ? 130.405 147.958 141.887 1.00 64.27  ? 293 VAL A C   1 
ATOM   2320 O  O   . VAL A 1 293 ? 130.456 148.760 140.949 1.00 71.62  ? 293 VAL A O   1 
ATOM   2321 C  CB  . VAL A 1 293 ? 131.475 148.567 144.107 1.00 58.67  ? 293 VAL A CB  1 
ATOM   2322 C  CG1 . VAL A 1 293 ? 132.607 149.043 143.211 1.00 57.06  ? 293 VAL A CG1 1 
ATOM   2323 C  CG2 . VAL A 1 293 ? 131.289 149.514 145.278 1.00 70.15  ? 293 VAL A CG2 1 
ATOM   2324 N  N   . GLN A 1 294 ? 130.557 146.646 141.701 1.00 64.46  ? 294 GLN A N   1 
ATOM   2325 C  CA  . GLN A 1 294 ? 130.775 146.091 140.369 1.00 58.14  ? 294 GLN A CA  1 
ATOM   2326 C  C   . GLN A 1 294 ? 129.580 146.343 139.460 1.00 57.13  ? 294 GLN A C   1 
ATOM   2327 O  O   . GLN A 1 294 ? 129.743 146.695 138.287 1.00 70.29  ? 294 GLN A O   1 
ATOM   2328 C  CB  . GLN A 1 294 ? 131.057 144.595 140.478 1.00 61.42  ? 294 GLN A CB  1 
ATOM   2329 C  CG  . GLN A 1 294 ? 131.408 143.930 139.172 1.00 65.15  ? 294 GLN A CG  1 
ATOM   2330 C  CD  . GLN A 1 294 ? 130.362 142.933 138.729 1.00 71.11  ? 294 GLN A CD  1 
ATOM   2331 O  OE1 . GLN A 1 294 ? 129.577 142.440 139.532 1.00 74.87  ? 294 GLN A OE1 1 
ATOM   2332 N  NE2 . GLN A 1 294 ? 130.355 142.627 137.442 1.00 77.15  ? 294 GLN A NE2 1 
ATOM   2333 N  N   . VAL A 1 295 ? 128.369 146.159 139.985 1.00 58.85  ? 295 VAL A N   1 
ATOM   2334 C  CA  . VAL A 1 295 ? 127.175 146.397 139.179 1.00 64.07  ? 295 VAL A CA  1 
ATOM   2335 C  C   . VAL A 1 295 ? 127.064 147.875 138.811 1.00 69.40  ? 295 VAL A C   1 
ATOM   2336 O  O   . VAL A 1 295 ? 126.709 148.228 137.678 1.00 74.91  ? 295 VAL A O   1 
ATOM   2337 C  CB  . VAL A 1 295 ? 125.931 145.884 139.926 1.00 62.24  ? 295 VAL A CB  1 
ATOM   2338 C  CG1 . VAL A 1 295 ? 124.678 146.441 139.321 1.00 64.62  ? 295 VAL A CG1 1 
ATOM   2339 C  CG2 . VAL A 1 295 ? 125.897 144.371 139.891 1.00 69.77  ? 295 VAL A CG2 1 
ATOM   2340 N  N   . LEU A 1 296 ? 127.384 148.761 139.758 1.00 69.81  ? 296 LEU A N   1 
ATOM   2341 C  CA  . LEU A 1 296 ? 127.378 150.192 139.464 1.00 61.36  ? 296 LEU A CA  1 
ATOM   2342 C  C   . LEU A 1 296 ? 128.409 150.543 138.397 1.00 70.13  ? 296 LEU A C   1 
ATOM   2343 O  O   . LEU A 1 296 ? 128.145 151.366 137.513 1.00 77.31  ? 296 LEU A O   1 
ATOM   2344 C  CB  . LEU A 1 296 ? 127.638 150.986 140.742 1.00 59.88  ? 296 LEU A CB  1 
ATOM   2345 C  CG  . LEU A 1 296 ? 126.453 151.155 141.694 1.00 66.42  ? 296 LEU A CG  1 
ATOM   2346 C  CD1 . LEU A 1 296 ? 126.805 152.109 142.820 1.00 72.44  ? 296 LEU A CD1 1 
ATOM   2347 C  CD2 . LEU A 1 296 ? 125.223 151.637 140.943 1.00 67.36  ? 296 LEU A CD2 1 
ATOM   2348 N  N   . LEU A 1 297 ? 129.610 149.995 138.412 1.00 70.70  ? 297 LEU A N   1 
ATOM   2349 C  CA  . LEU A 1 297 ? 130.678 150.177 137.395 1.00 58.80  ? 297 LEU A CA  1 
ATOM   2350 C  C   . LEU A 1 297 ? 130.257 149.616 136.031 1.00 65.42  ? 297 LEU A C   1 
ATOM   2351 O  O   . LEU A 1 297 ? 130.675 150.120 135.037 1.00 75.70  ? 297 LEU A O   1 
ATOM   2352 C  CB  . LEU A 1 297 ? 131.971 149.488 137.854 1.00 50.87  ? 297 LEU A CB  1 
ATOM   2353 C  CG  . LEU A 1 297 ? 132.730 150.092 139.029 1.00 61.55  ? 297 LEU A CG  1 
ATOM   2354 C  CD1 . LEU A 1 297 ? 133.708 149.079 139.587 1.00 69.41  ? 297 LEU A CD1 1 
ATOM   2355 C  CD2 . LEU A 1 297 ? 133.452 151.359 138.616 1.00 63.28  ? 297 LEU A CD2 1 
ATOM   2356 N  N   . GLY A 1 298 ? 129.488 148.553 136.046 1.00 65.82  ? 298 GLY A N   1 
ATOM   2357 C  CA  . GLY A 1 298 ? 128.941 148.090 134.781 1.00 70.43  ? 298 GLY A CA  1 
ATOM   2358 C  C   . GLY A 1 298 ? 127.918 149.053 134.209 1.00 74.98  ? 298 GLY A C   1 
ATOM   2359 O  O   . GLY A 1 298 ? 127.917 149.336 133.007 1.00 77.72  ? 298 GLY A O   1 
ATOM   2360 N  N   . GLY A 1 299 ? 127.037 149.571 135.063 1.00 72.44  ? 299 GLY A N   1 
ATOM   2361 C  CA  . GLY A 1 299 ? 126.103 150.587 134.608 1.00 76.07  ? 299 GLY A CA  1 
ATOM   2362 C  C   . GLY A 1 299 ? 126.805 151.835 134.107 1.00 74.11  ? 299 GLY A C   1 
ATOM   2363 O  O   . GLY A 1 299 ? 126.352 152.479 133.158 1.00 75.60  ? 299 GLY A O   1 
ATOM   2364 N  N   . LEU A 1 300 ? 127.924 152.191 134.740 1.00 64.48  ? 300 LEU A N   1 
ATOM   2365 C  CA  . LEU A 1 300 ? 128.665 153.382 134.336 1.00 61.96  ? 300 LEU A CA  1 
ATOM   2366 C  C   . LEU A 1 300 ? 129.360 153.177 132.993 1.00 72.03  ? 300 LEU A C   1 
ATOM   2367 O  O   . LEU A 1 300 ? 129.363 154.073 132.143 1.00 80.63  ? 300 LEU A O   1 
ATOM   2368 C  CB  . LEU A 1 300 ? 129.676 153.755 135.418 1.00 64.13  ? 300 LEU A CB  1 
ATOM   2369 C  CG  . LEU A 1 300 ? 130.560 154.974 135.151 1.00 68.18  ? 300 LEU A CG  1 
ATOM   2370 C  CD1 . LEU A 1 300 ? 129.711 156.197 134.868 1.00 73.42  ? 300 LEU A CD1 1 
ATOM   2371 C  CD2 . LEU A 1 300 ? 131.480 155.221 136.332 1.00 72.21  ? 300 LEU A CD2 1 
ATOM   2372 N  N   . THR A 1 301 ? 129.967 152.010 132.688 1.00 71.99  ? 301 THR A N   1 
ATOM   2373 C  CA  . THR A 1 301 ? 130.562 151.613 131.369 1.00 63.26  ? 301 THR A CA  1 
ATOM   2374 C  C   . THR A 1 301 ? 129.553 151.573 130.203 1.00 71.97  ? 301 THR A C   1 
ATOM   2375 O  O   . THR A 1 301 ? 129.933 151.992 129.119 1.00 78.91  ? 301 THR A O   1 
ATOM   2376 C  CB  . THR A 1 301 ? 131.468 150.339 131.492 1.00 61.02  ? 301 THR A CB  1 
ATOM   2377 O  OG1 . THR A 1 301 ? 132.048 149.894 130.266 1.00 73.43  ? 301 THR A OG1 1 
ATOM   2378 C  CG2 . THR A 1 301 ? 130.778 149.124 132.066 1.00 71.42  ? 301 THR A CG2 1 
ATOM   2379 N  N   . ALA A 1 302 ? 128.339 151.109 130.418 1.00 82.58  ? 302 ALA A N   1 
ATOM   2380 C  CA  . ALA A 1 302 ? 127.256 151.125 129.425 1.00 78.40  ? 302 ALA A CA  1 
ATOM   2381 C  C   . ALA A 1 302 ? 126.936 152.561 129.072 1.00 83.30  ? 302 ALA A C   1 
ATOM   2382 O  O   . ALA A 1 302 ? 126.659 152.847 127.930 1.00 89.51  ? 302 ALA A O   1 
ATOM   2383 C  CB  . ALA A 1 302 ? 126.082 150.389 129.969 1.00 75.03  ? 302 ALA A CB  1 
ATOM   2384 N  N   . HIS A 1 303 ? 127.015 153.430 130.050 1.00 90.98  ? 303 HIS A N   1 
ATOM   2385 C  CA  . HIS A 1 303 ? 126.650 154.782 129.639 1.00 87.18  ? 303 HIS A CA  1 
ATOM   2386 C  C   . HIS A 1 303 ? 127.662 155.366 128.661 1.00 87.01  ? 303 HIS A C   1 
ATOM   2387 O  O   . HIS A 1 303 ? 127.300 156.202 127.826 1.00 97.68  ? 303 HIS A O   1 
ATOM   2388 C  CB  . HIS A 1 303 ? 126.511 155.672 130.875 1.00 87.54  ? 303 HIS A CB  1 
ATOM   2389 C  CG  . HIS A 1 303 ? 126.401 157.132 130.565 1.00 91.20  ? 303 HIS A CG  1 
ATOM   2390 N  ND1 . HIS A 1 303 ? 127.465 157.999 130.682 1.00 97.54  ? 303 HIS A ND1 1 
ATOM   2391 C  CD2 . HIS A 1 303 ? 125.350 157.878 130.153 1.00 91.70  ? 303 HIS A CD2 1 
ATOM   2392 C  CE1 . HIS A 1 303 ? 127.076 159.216 130.351 1.00 99.33  ? 303 HIS A CE1 1 
ATOM   2393 N  NE2 . HIS A 1 303 ? 125.797 159.172 130.027 1.00 99.26  ? 303 HIS A NE2 1 
ATOM   2394 N  N   . TYR A 1 304 ? 128.922 154.938 128.745 1.00 87.23  ? 304 TYR A N   1 
ATOM   2395 C  CA  . TYR A 1 304 ? 129.940 155.406 127.810 1.00 89.53  ? 304 TYR A CA  1 
ATOM   2396 C  C   . TYR A 1 304 ? 129.694 154.916 126.390 1.00 93.17  ? 304 TYR A C   1 
ATOM   2397 O  O   . TYR A 1 304 ? 130.154 155.557 125.440 1.00 91.22  ? 304 TYR A O   1 
ATOM   2398 C  CB  . TYR A 1 304 ? 131.326 154.954 128.268 1.00 88.14  ? 304 TYR A CB  1 
ATOM   2399 C  CG  . TYR A 1 304 ? 131.978 155.871 129.271 1.00 85.03  ? 304 TYR A CG  1 
ATOM   2400 C  CD1 . TYR A 1 304 ? 132.087 157.231 129.028 1.00 84.64  ? 304 TYR A CD1 1 
ATOM   2401 C  CD2 . TYR A 1 304 ? 132.485 155.377 130.463 1.00 93.20  ? 304 TYR A CD2 1 
ATOM   2402 C  CE1 . TYR A 1 304 ? 132.683 158.073 129.943 1.00 88.26  ? 304 TYR A CE1 1 
ATOM   2403 C  CE2 . TYR A 1 304 ? 133.081 156.209 131.382 1.00 96.54  ? 304 TYR A CE2 1 
ATOM   2404 C  CZ  . TYR A 1 304 ? 133.179 157.556 131.118 1.00 95.15  ? 304 TYR A CZ  1 
ATOM   2405 O  OH  . TYR A 1 304 ? 133.775 158.389 132.034 1.00 101.56 ? 304 TYR A OH  1 
ATOM   2406 N  N   . THR A 1 305 ? 128.991 153.799 126.222 1.00 91.21  ? 305 THR A N   1 
ATOM   2407 C  CA  . THR A 1 305 ? 128.744 153.241 124.899 1.00 86.75  ? 305 THR A CA  1 
ATOM   2408 C  C   . THR A 1 305 ? 127.660 153.984 124.128 1.00 94.69  ? 305 THR A C   1 
ATOM   2409 O  O   . THR A 1 305 ? 127.498 153.734 122.931 1.00 98.23  ? 305 THR A O   1 
ATOM   2410 C  CB  . THR A 1 305 ? 128.366 151.763 125.012 1.00 84.41  ? 305 THR A CB  1 
ATOM   2411 O  OG1 . THR A 1 305 ? 127.152 151.634 125.762 1.00 90.05  ? 305 THR A OG1 1 
ATOM   2412 C  CG2 . THR A 1 305 ? 129.468 150.986 125.709 1.00 80.70  ? 305 THR A CG2 1 
ATOM   2413 N  N   . VAL A 1 306 ? 126.925 154.885 124.775 1.00 99.32  ? 306 VAL A N   1 
ATOM   2414 C  CA  . VAL A 1 306 ? 125.879 155.651 124.108 1.00 97.49  ? 306 VAL A CA  1 
ATOM   2415 C  C   . VAL A 1 306 ? 126.157 157.145 124.086 1.00 100.08 ? 306 VAL A C   1 
ATOM   2416 O  O   . VAL A 1 306 ? 125.555 157.856 123.269 1.00 103.62 ? 306 VAL A O   1 
ATOM   2417 C  CB  . VAL A 1 306 ? 124.493 155.387 124.737 1.00 97.58  ? 306 VAL A CB  1 
ATOM   2418 C  CG1 . VAL A 1 306 ? 124.194 153.901 124.761 1.00 100.86 ? 306 VAL A CG1 1 
ATOM   2419 C  CG2 . VAL A 1 306 ? 124.424 155.967 126.137 1.00 97.37  ? 306 VAL A CG2 1 
ATOM   2420 N  N   . GLU A 1 307 ? 127.041 157.651 124.944 1.00 115.82 ? 307 GLU A N   1 
ATOM   2421 C  CA  . GLU A 1 307 ? 127.313 159.082 124.989 1.00 115.61 ? 307 GLU A CA  1 
ATOM   2422 C  C   . GLU A 1 307 ? 128.765 159.366 124.627 1.00 119.40 ? 307 GLU A C   1 
ATOM   2423 O  O   . GLU A 1 307 ? 129.049 160.283 123.849 1.00 122.83 ? 307 GLU A O   1 
ATOM   2424 C  CB  . GLU A 1 307 ? 126.980 159.647 126.371 1.00 115.02 ? 307 GLU A CB  1 
ATOM   2425 C  CG  . GLU A 1 307 ? 125.507 159.555 126.730 1.00 121.58 ? 307 GLU A CG  1 
ATOM   2426 C  CD  . GLU A 1 307 ? 124.761 160.853 126.494 1.00 128.20 ? 307 GLU A CD  1 
ATOM   2427 O  OE1 . GLU A 1 307 ? 124.617 161.254 125.319 1.00 127.29 ? 307 GLU A OE1 1 
ATOM   2428 O  OE2 . GLU A 1 307 ? 124.314 161.473 127.482 1.00 129.69 ? 307 GLU A OE2 1 
ATOM   2429 N  N   . GLY A 1 308 ? 129.690 158.591 125.186 1.00 116.75 ? 308 GLY A N   1 
ATOM   2430 C  CA  . GLY A 1 308 ? 131.086 158.702 124.812 1.00 117.55 ? 308 GLY A CA  1 
ATOM   2431 C  C   . GLY A 1 308 ? 131.968 159.384 125.838 1.00 119.11 ? 308 GLY A C   1 
ATOM   2432 O  O   . GLY A 1 308 ? 133.081 158.920 126.103 1.00 123.32 ? 308 GLY A O   1 
ATOM   2433 N  N   . GLN A 1 309 ? 131.494 160.480 126.415 1.00 124.31 ? 309 GLN A N   1 
ATOM   2434 C  CA  . GLN A 1 309 ? 132.280 161.189 127.421 1.00 125.29 ? 309 GLN A CA  1 
ATOM   2435 C  C   . GLN A 1 309 ? 131.532 161.408 128.728 1.00 126.31 ? 309 GLN A C   1 
ATOM   2436 O  O   . GLN A 1 309 ? 132.148 161.349 129.794 1.00 127.35 ? 309 GLN A O   1 
ATOM   2437 C  CB  . GLN A 1 309 ? 132.766 162.540 126.865 1.00 124.05 ? 309 GLN A CB  1 
ATOM   2438 C  CG  . GLN A 1 309 ? 133.332 162.477 125.450 1.00 125.58 ? 309 GLN A CG  1 
ATOM   2439 C  CD  . GLN A 1 309 ? 134.787 162.035 125.409 1.00 126.84 ? 309 GLN A CD  1 
ATOM   2440 O  OE1 . GLN A 1 309 ? 135.210 161.179 126.183 1.00 130.56 ? 309 GLN A OE1 1 
ATOM   2441 N  NE2 . GLN A 1 309 ? 135.558 162.619 124.500 1.00 122.46 ? 309 GLN A NE2 1 
ATOM   2442 N  N   . GLY A 1 310 ? 130.232 161.661 128.678 1.00 140.47 ? 310 GLY A N   1 
ATOM   2443 C  CA  . GLY A 1 310 ? 129.461 161.805 129.894 1.00 141.57 ? 310 GLY A CA  1 
ATOM   2444 C  C   . GLY A 1 310 ? 128.272 162.724 129.687 1.00 142.59 ? 310 GLY A C   1 
ATOM   2445 O  O   . GLY A 1 310 ? 128.021 163.213 128.586 1.00 141.10 ? 310 GLY A O   1 
ATOM   2446 N  N   . PHE A 1 311 ? 127.549 162.944 130.784 1.00 152.87 ? 311 PHE A N   1 
ATOM   2447 C  CA  . PHE A 1 311 ? 126.376 163.805 130.780 1.00 153.93 ? 311 PHE A CA  1 
ATOM   2448 C  C   . PHE A 1 311 ? 126.433 164.714 131.998 1.00 156.41 ? 311 PHE A C   1 
ATOM   2449 O  O   . PHE A 1 311 ? 126.874 164.303 133.075 1.00 154.38 ? 311 PHE A O   1 
ATOM   2450 C  CB  . PHE A 1 311 ? 125.078 162.982 130.771 1.00 152.41 ? 311 PHE A CB  1 
ATOM   2451 C  CG  . PHE A 1 311 ? 124.934 162.052 131.948 1.00 152.97 ? 311 PHE A CG  1 
ATOM   2452 C  CD1 . PHE A 1 311 ? 124.354 162.488 133.129 1.00 152.35 ? 311 PHE A CD1 1 
ATOM   2453 C  CD2 . PHE A 1 311 ? 125.395 160.747 131.873 1.00 153.20 ? 311 PHE A CD2 1 
ATOM   2454 C  CE1 . PHE A 1 311 ? 124.225 161.636 134.209 1.00 152.95 ? 311 PHE A CE1 1 
ATOM   2455 C  CE2 . PHE A 1 311 ? 125.268 159.891 132.953 1.00 153.03 ? 311 PHE A CE2 1 
ATOM   2456 C  CZ  . PHE A 1 311 ? 124.685 160.336 134.121 1.00 152.63 ? 311 PHE A CZ  1 
ATOM   2457 N  N   . TYR A 1 312 ? 125.962 165.950 131.816 1.00 164.88 ? 312 TYR A N   1 
ATOM   2458 C  CA  . TYR A 1 312 ? 126.001 166.983 132.845 1.00 163.02 ? 312 TYR A CA  1 
ATOM   2459 C  C   . TYR A 1 312 ? 127.389 167.101 133.462 1.00 162.84 ? 312 TYR A C   1 
ATOM   2460 O  O   . TYR A 1 312 ? 128.381 167.249 132.740 1.00 162.34 ? 312 TYR A O   1 
ATOM   2461 C  CB  . TYR A 1 312 ? 124.962 166.698 133.931 1.00 158.60 ? 312 TYR A CB  1 
ATOM   2462 N  N   . GLY A 1 313 ? 127.464 167.011 134.793 1.00 153.41 ? 313 GLY A N   1 
ATOM   2463 C  CA  . GLY A 1 313 ? 128.721 167.103 135.528 1.00 152.74 ? 313 GLY A CA  1 
ATOM   2464 C  C   . GLY A 1 313 ? 129.558 168.292 135.068 1.00 154.09 ? 313 GLY A C   1 
ATOM   2465 O  O   . GLY A 1 313 ? 130.678 168.118 134.580 1.00 153.71 ? 313 GLY A O   1 
ATOM   2466 N  N   . ILE A 1 314 ? 129.014 169.498 135.209 1.00 30.00  ? 314 ILE A N   1 
ATOM   2467 C  CA  . ILE A 1 314 ? 129.673 170.714 134.740 1.00 30.00  ? 314 ILE A CA  1 
ATOM   2468 C  C   . ILE A 1 314 ? 131.031 170.920 135.402 1.00 30.00  ? 314 ILE A C   1 
ATOM   2469 O  O   . ILE A 1 314 ? 132.070 170.639 134.810 1.00 30.00  ? 314 ILE A O   1 
ATOM   2470 C  CB  . ILE A 1 314 ? 128.781 171.921 134.982 1.00 30.00  ? 314 ILE A CB  1 
ATOM   2471 N  N   . LEU A 1 318 ? 132.923 167.435 140.380 1.00 147.09 ? 318 LEU A N   1 
ATOM   2472 C  CA  . LEU A 1 318 ? 132.021 167.774 139.286 1.00 151.67 ? 318 LEU A CA  1 
ATOM   2473 C  C   . LEU A 1 318 ? 132.694 168.763 138.341 1.00 154.22 ? 318 LEU A C   1 
ATOM   2474 O  O   . LEU A 1 318 ? 132.323 168.870 137.174 1.00 151.35 ? 318 LEU A O   1 
ATOM   2475 C  CB  . LEU A 1 318 ? 130.699 168.330 139.844 1.00 153.40 ? 318 LEU A CB  1 
ATOM   2476 C  CG  . LEU A 1 318 ? 129.626 169.020 138.989 1.00 156.51 ? 318 LEU A CG  1 
ATOM   2477 C  CD1 . LEU A 1 318 ? 128.308 168.990 139.735 1.00 153.52 ? 318 LEU A CD1 1 
ATOM   2478 C  CD2 . LEU A 1 318 ? 129.976 170.467 138.671 1.00 152.00 ? 318 LEU A CD2 1 
ATOM   2479 N  N   . GLY A 1 319 ? 133.704 169.471 138.845 1.00 155.68 ? 319 GLY A N   1 
ATOM   2480 C  CA  . GLY A 1 319 ? 134.375 170.496 138.074 1.00 154.36 ? 319 GLY A CA  1 
ATOM   2481 C  C   . GLY A 1 319 ? 135.362 170.009 137.038 1.00 156.23 ? 319 GLY A C   1 
ATOM   2482 O  O   . GLY A 1 319 ? 135.915 170.824 136.295 1.00 155.22 ? 319 GLY A O   1 
ATOM   2483 N  N   . PHE A 1 320 ? 135.599 168.704 136.964 1.00 147.52 ? 320 PHE A N   1 
ATOM   2484 C  CA  . PHE A 1 320 ? 136.533 168.137 136.003 1.00 145.97 ? 320 PHE A CA  1 
ATOM   2485 C  C   . PHE A 1 320 ? 135.790 167.457 134.857 1.00 143.44 ? 320 PHE A C   1 
ATOM   2486 O  O   . PHE A 1 320 ? 134.563 167.353 134.845 1.00 143.34 ? 320 PHE A O   1 
ATOM   2487 C  CB  . PHE A 1 320 ? 137.496 167.165 136.707 1.00 144.39 ? 320 PHE A CB  1 
ATOM   2488 C  CG  . PHE A 1 320 ? 136.819 166.004 137.412 1.00 143.15 ? 320 PHE A CG  1 
ATOM   2489 C  CD1 . PHE A 1 320 ? 136.546 164.837 136.719 1.00 142.29 ? 320 PHE A CD1 1 
ATOM   2490 C  CD2 . PHE A 1 320 ? 136.413 166.092 138.735 1.00 143.75 ? 320 PHE A CD2 1 
ATOM   2491 C  CE1 . PHE A 1 320 ? 135.919 163.772 137.338 1.00 140.95 ? 320 PHE A CE1 1 
ATOM   2492 C  CE2 . PHE A 1 320 ? 135.788 165.030 139.359 1.00 143.48 ? 320 PHE A CE2 1 
ATOM   2493 C  CZ  . PHE A 1 320 ? 135.539 163.870 138.659 1.00 141.93 ? 320 PHE A CZ  1 
ATOM   2494 N  N   . GLU A 1 321 ? 136.562 166.992 133.878 1.00 128.51 ? 321 GLU A N   1 
ATOM   2495 C  CA  . GLU A 1 321 ? 136.037 166.160 132.798 1.00 128.18 ? 321 GLU A CA  1 
ATOM   2496 C  C   . GLU A 1 321 ? 136.185 164.710 133.238 1.00 130.51 ? 321 GLU A C   1 
ATOM   2497 O  O   . GLU A 1 321 ? 137.297 164.223 133.451 1.00 132.86 ? 321 GLU A O   1 
ATOM   2498 C  CB  . GLU A 1 321 ? 136.768 166.439 131.489 1.00 125.06 ? 321 GLU A CB  1 
ATOM   2499 C  CG  . GLU A 1 321 ? 136.231 165.663 130.299 1.00 126.28 ? 321 GLU A CG  1 
ATOM   2500 C  CD  . GLU A 1 321 ? 136.947 166.000 129.008 1.00 132.17 ? 321 GLU A CD  1 
ATOM   2501 O  OE1 . GLU A 1 321 ? 137.891 166.815 129.049 1.00 132.35 ? 321 GLU A OE1 1 
ATOM   2502 O  OE2 . GLU A 1 321 ? 136.564 165.450 127.955 1.00 135.14 ? 321 GLU A OE2 1 
ATOM   2503 N  N   . MET A 1 322 ? 135.134 163.881 133.206 1.00 122.07 ? 322 MET A N   1 
ATOM   2504 C  CA  . MET A 1 322 ? 135.210 162.513 133.827 1.00 117.48 ? 322 MET A CA  1 
ATOM   2505 C  C   . MET A 1 322 ? 135.947 161.441 133.012 1.00 116.26 ? 322 MET A C   1 
ATOM   2506 O  O   . MET A 1 322 ? 136.481 160.555 133.646 1.00 117.49 ? 322 MET A O   1 
ATOM   2507 C  CB  . MET A 1 322 ? 133.815 161.993 134.202 1.00 117.78 ? 322 MET A CB  1 
ATOM   2508 C  CG  . MET A 1 322 ? 133.762 161.298 135.538 1.00 116.31 ? 322 MET A CG  1 
ATOM   2509 S  SD  . MET A 1 322 ? 132.744 159.821 135.424 1.00 126.47 ? 322 MET A SD  1 
ATOM   2510 C  CE  . MET A 1 322 ? 133.305 158.925 136.869 1.00 119.39 ? 322 MET A CE  1 
ATOM   2511 N  N   . SER A 1 323 ? 135.952 161.510 131.688 1.00 112.84 ? 323 SER A N   1 
ATOM   2512 C  CA  . SER A 1 323 ? 136.671 160.548 130.799 1.00 111.13 ? 323 SER A CA  1 
ATOM   2513 C  C   . SER A 1 323 ? 138.156 160.815 130.858 1.00 111.46 ? 323 SER A C   1 
ATOM   2514 O  O   . SER A 1 323 ? 138.903 159.957 130.452 1.00 114.32 ? 323 SER A O   1 
ATOM   2515 C  CB  . SER A 1 323 ? 136.171 160.583 129.363 1.00 109.24 ? 323 SER A CB  1 
ATOM   2516 O  OG  . SER A 1 323 ? 136.495 161.798 128.713 1.00 107.43 ? 323 SER A OG  1 
ATOM   2517 N  N   . ASP A 1 324 ? 138.543 162.007 131.244 1.00 113.07 ? 324 ASP A N   1 
ATOM   2518 C  CA  . ASP A 1 324 ? 139.983 162.249 131.449 1.00 111.71 ? 324 ASP A CA  1 
ATOM   2519 C  C   . ASP A 1 324 ? 140.452 161.443 132.668 1.00 111.82 ? 324 ASP A C   1 
ATOM   2520 O  O   . ASP A 1 324 ? 141.548 160.987 132.661 1.00 112.44 ? 324 ASP A O   1 
ATOM   2521 C  CB  . ASP A 1 324 ? 140.281 163.742 131.537 1.00 115.08 ? 324 ASP A CB  1 
ATOM   2522 C  CG  . ASP A 1 324 ? 140.431 164.448 130.207 1.00 117.30 ? 324 ASP A CG  1 
ATOM   2523 O  OD1 . ASP A 1 324 ? 140.539 163.751 129.189 1.00 118.97 ? 324 ASP A OD1 1 
ATOM   2524 O  OD2 . ASP A 1 324 ? 140.439 165.684 130.206 1.00 116.21 ? 324 ASP A OD2 1 
ATOM   2525 N  N   . TRP A 1 325 ? 139.607 161.281 133.672 1.00 109.59 ? 325 TRP A N   1 
ATOM   2526 C  CA  . TRP A 1 325 ? 140.106 160.653 134.888 1.00 107.04 ? 325 TRP A CA  1 
ATOM   2527 C  C   . TRP A 1 325 ? 139.534 159.271 135.153 1.00 108.52 ? 325 TRP A C   1 
ATOM   2528 O  O   . TRP A 1 325 ? 140.240 158.431 135.714 1.00 112.46 ? 325 TRP A O   1 
ATOM   2529 C  CB  . TRP A 1 325 ? 139.831 161.553 136.098 1.00 104.69 ? 325 TRP A CB  1 
ATOM   2530 C  CG  . TRP A 1 325 ? 140.523 162.874 135.996 1.00 107.36 ? 325 TRP A CG  1 
ATOM   2531 C  CD1 . TRP A 1 325 ? 139.967 164.061 135.626 1.00 108.88 ? 325 TRP A CD1 1 
ATOM   2532 C  CD2 . TRP A 1 325 ? 141.908 163.138 136.242 1.00 114.25 ? 325 TRP A CD2 1 
ATOM   2533 N  NE1 . TRP A 1 325 ? 140.917 165.052 135.638 1.00 110.29 ? 325 TRP A NE1 1 
ATOM   2534 C  CE2 . TRP A 1 325 ? 142.118 164.511 136.012 1.00 116.17 ? 325 TRP A CE2 1 
ATOM   2535 C  CE3 . TRP A 1 325 ? 142.990 162.348 136.643 1.00 113.52 ? 325 TRP A CE3 1 
ATOM   2536 C  CZ2 . TRP A 1 325 ? 143.365 165.111 136.170 1.00 115.70 ? 325 TRP A CZ2 1 
ATOM   2537 C  CZ3 . TRP A 1 325 ? 144.228 162.945 136.798 1.00 111.69 ? 325 TRP A CZ3 1 
ATOM   2538 C  CH2 . TRP A 1 325 ? 144.405 164.312 136.561 1.00 110.99 ? 325 TRP A CH2 1 
ATOM   2539 N  N   . PHE A 1 326 ? 138.288 159.004 134.769 1.00 90.41  ? 326 PHE A N   1 
ATOM   2540 C  CA  . PHE A 1 326 ? 137.682 157.682 134.903 1.00 80.87  ? 326 PHE A CA  1 
ATOM   2541 C  C   . PHE A 1 326 ? 137.096 157.311 133.549 1.00 82.60  ? 326 PHE A C   1 
ATOM   2542 O  O   . PHE A 1 326 ? 135.872 157.319 133.365 1.00 84.93  ? 326 PHE A O   1 
ATOM   2543 C  CB  . PHE A 1 326 ? 136.616 157.666 135.999 1.00 82.19  ? 326 PHE A CB  1 
ATOM   2544 C  CG  . PHE A 1 326 ? 137.106 158.171 137.322 1.00 85.26  ? 326 PHE A CG  1 
ATOM   2545 C  CD1 . PHE A 1 326 ? 137.745 157.322 138.207 1.00 86.92  ? 326 PHE A CD1 1 
ATOM   2546 C  CD2 . PHE A 1 326 ? 136.934 159.496 137.679 1.00 89.85  ? 326 PHE A CD2 1 
ATOM   2547 C  CE1 . PHE A 1 326 ? 138.201 157.785 139.422 1.00 89.07  ? 326 PHE A CE1 1 
ATOM   2548 C  CE2 . PHE A 1 326 ? 137.387 159.964 138.893 1.00 90.50  ? 326 PHE A CE2 1 
ATOM   2549 C  CZ  . PHE A 1 326 ? 138.021 159.107 139.766 1.00 89.92  ? 326 PHE A CZ  1 
ATOM   2550 N  N   . PRO A 1 327 ? 137.938 156.987 132.577 1.00 76.00  ? 327 PRO A N   1 
ATOM   2551 C  CA  . PRO A 1 327 ? 137.455 156.704 131.227 1.00 74.99  ? 327 PRO A CA  1 
ATOM   2552 C  C   . PRO A 1 327 ? 136.791 155.333 131.150 1.00 83.89  ? 327 PRO A C   1 
ATOM   2553 O  O   . PRO A 1 327 ? 136.698 154.592 132.131 1.00 91.71  ? 327 PRO A O   1 
ATOM   2554 C  CB  . PRO A 1 327 ? 138.729 156.758 130.383 1.00 77.09  ? 327 PRO A CB  1 
ATOM   2555 C  CG  . PRO A 1 327 ? 139.806 156.365 131.318 1.00 80.12  ? 327 PRO A CG  1 
ATOM   2556 C  CD  . PRO A 1 327 ? 139.404 156.864 132.676 1.00 79.26  ? 327 PRO A CD  1 
ATOM   2557 N  N   . TYR A 1 328 ? 136.315 155.015 129.944 1.00 80.67  ? 328 TYR A N   1 
ATOM   2558 C  CA  . TYR A 1 328 ? 135.675 153.731 129.693 1.00 77.39  ? 328 TYR A CA  1 
ATOM   2559 C  C   . TYR A 1 328 ? 136.620 152.574 129.968 1.00 77.94  ? 328 TYR A C   1 
ATOM   2560 O  O   . TYR A 1 328 ? 136.198 151.544 130.501 1.00 81.71  ? 328 TYR A O   1 
ATOM   2561 C  CB  . TYR A 1 328 ? 135.166 153.692 128.250 1.00 70.58  ? 328 TYR A CB  1 
ATOM   2562 C  CG  . TYR A 1 328 ? 134.868 152.314 127.695 1.00 72.95  ? 328 TYR A CG  1 
ATOM   2563 C  CD1 . TYR A 1 328 ? 133.591 151.778 127.771 1.00 71.12  ? 328 TYR A CD1 1 
ATOM   2564 C  CD2 . TYR A 1 328 ? 135.855 151.565 127.066 1.00 78.23  ? 328 TYR A CD2 1 
ATOM   2565 C  CE1 . TYR A 1 328 ? 133.311 150.530 127.254 1.00 74.69  ? 328 TYR A CE1 1 
ATOM   2566 C  CE2 . TYR A 1 328 ? 135.584 150.317 126.556 1.00 75.28  ? 328 TYR A CE2 1 
ATOM   2567 C  CZ  . TYR A 1 328 ? 134.312 149.805 126.647 1.00 79.39  ? 328 TYR A CZ  1 
ATOM   2568 O  OH  . TYR A 1 328 ? 134.040 148.559 126.132 1.00 86.65  ? 328 TYR A OH  1 
ATOM   2569 N  N   . ALA A 1 329 ? 137.898 152.720 129.611 1.00 65.07  ? 329 ALA A N   1 
ATOM   2570 C  CA  . ALA A 1 329 ? 138.859 151.648 129.850 1.00 65.01  ? 329 ALA A CA  1 
ATOM   2571 C  C   . ALA A 1 329 ? 139.002 151.353 131.337 1.00 70.98  ? 329 ALA A C   1 
ATOM   2572 O  O   . ALA A 1 329 ? 138.940 150.188 131.753 1.00 78.12  ? 329 ALA A O   1 
ATOM   2573 C  CB  . ALA A 1 329 ? 140.211 152.014 129.243 1.00 65.54  ? 329 ALA A CB  1 
ATOM   2574 N  N   . LEU A 1 330 ? 139.152 152.359 132.152 1.00 65.83  ? 330 LEU A N   1 
ATOM   2575 C  CA  . LEU A 1 330 ? 139.255 152.210 133.595 1.00 61.95  ? 330 LEU A CA  1 
ATOM   2576 C  C   . LEU A 1 330 ? 137.995 151.603 134.209 1.00 76.59  ? 330 LEU A C   1 
ATOM   2577 O  O   . LEU A 1 330 ? 138.082 150.752 135.060 1.00 89.23  ? 330 LEU A O   1 
ATOM   2578 C  CB  . LEU A 1 330 ? 139.523 153.614 134.146 1.00 59.49  ? 330 LEU A CB  1 
ATOM   2579 C  CG  . LEU A 1 330 ? 139.727 153.621 135.667 1.00 63.13  ? 330 LEU A CG  1 
ATOM   2580 C  CD1 . LEU A 1 330 ? 140.995 152.886 136.068 1.00 69.77  ? 330 LEU A CD1 1 
ATOM   2581 C  CD2 . LEU A 1 330 ? 139.697 155.019 136.250 1.00 73.64  ? 330 LEU A CD2 1 
ATOM   2582 N  N   . THR A 1 331 ? 136.833 152.119 133.806 1.00 72.04  ? 331 THR A N   1 
ATOM   2583 C  CA  . THR A 1 331 ? 135.525 151.665 134.330 1.00 62.48  ? 331 THR A CA  1 
ATOM   2584 C  C   . THR A 1 331 ? 135.309 150.188 133.941 1.00 69.02  ? 331 THR A C   1 
ATOM   2585 O  O   . THR A 1 331 ? 134.768 149.491 134.773 1.00 84.19  ? 331 THR A O   1 
ATOM   2586 C  CB  . THR A 1 331 ? 134.353 152.655 134.046 1.00 62.15  ? 331 THR A CB  1 
ATOM   2587 O  OG1 . THR A 1 331 ? 133.844 152.578 132.710 1.00 75.40  ? 331 THR A OG1 1 
ATOM   2588 C  CG2 . THR A 1 331 ? 134.668 154.090 134.414 1.00 76.77  ? 331 THR A CG2 1 
ATOM   2589 N  N   . ARG A 1 332 ? 135.701 149.791 132.734 1.00 61.88  ? 332 ARG A N   1 
ATOM   2590 C  CA  . ARG A 1 332 ? 135.531 148.398 132.337 1.00 61.06  ? 332 ARG A CA  1 
ATOM   2591 C  C   . ARG A 1 332 ? 136.520 147.492 133.064 1.00 71.41  ? 332 ARG A C   1 
ATOM   2592 O  O   . ARG A 1 332 ? 136.167 146.376 133.472 1.00 78.74  ? 332 ARG A O   1 
ATOM   2593 C  CB  . ARG A 1 332 ? 135.692 148.273 130.824 1.00 52.64  ? 332 ARG A CB  1 
ATOM   2594 C  CG  . ARG A 1 332 ? 135.230 146.953 130.248 1.00 56.32  ? 332 ARG A CG  1 
ATOM   2595 C  CD  . ARG A 1 332 ? 135.500 146.884 128.759 1.00 56.13  ? 332 ARG A CD  1 
ATOM   2596 N  NE  . ARG A 1 332 ? 134.890 145.710 128.153 1.00 56.41  ? 332 ARG A NE  1 
ATOM   2597 C  CZ  . ARG A 1 332 ? 135.437 144.503 128.126 1.00 64.67  ? 332 ARG A CZ  1 
ATOM   2598 N  NH1 . ARG A 1 332 ? 136.615 144.266 128.676 1.00 63.01  ? 332 ARG A NH1 1 
ATOM   2599 N  NH2 . ARG A 1 332 ? 134.781 143.507 127.539 1.00 73.98  ? 332 ARG A NH2 1 
ATOM   2600 N  N   . THR A 1 333 ? 137.762 147.955 133.232 1.00 64.23  ? 333 THR A N   1 
ATOM   2601 C  CA  . THR A 1 333 ? 138.745 147.186 133.989 1.00 58.31  ? 333 THR A CA  1 
ATOM   2602 C  C   . THR A 1 333 ? 138.258 146.927 135.404 1.00 58.00  ? 333 THR A C   1 
ATOM   2603 O  O   . THR A 1 333 ? 138.282 145.787 135.887 1.00 70.03  ? 333 THR A O   1 
ATOM   2604 C  CB  . THR A 1 333 ? 140.079 147.933 134.019 1.00 62.10  ? 333 THR A CB  1 
ATOM   2605 O  OG1 . THR A 1 333 ? 140.614 148.025 132.695 1.00 61.98  ? 333 THR A OG1 1 
ATOM   2606 C  CG2 . THR A 1 333 ? 141.072 147.217 134.915 1.00 71.32  ? 333 THR A CG2 1 
ATOM   2607 N  N   . TRP A 1 334 ? 137.805 147.981 136.086 1.00 58.15  ? 334 TRP A N   1 
ATOM   2608 C  CA  . TRP A 1 334 ? 137.309 147.820 137.447 1.00 63.26  ? 334 TRP A CA  1 
ATOM   2609 C  C   . TRP A 1 334 ? 136.071 146.936 137.477 1.00 70.06  ? 334 TRP A C   1 
ATOM   2610 O  O   . TRP A 1 334 ? 135.893 146.137 138.402 1.00 78.15  ? 334 TRP A O   1 
ATOM   2611 C  CB  . TRP A 1 334 ? 137.016 149.185 138.064 1.00 67.73  ? 334 TRP A CB  1 
ATOM   2612 C  CG  . TRP A 1 334 ? 138.252 149.931 138.441 1.00 74.48  ? 334 TRP A CG  1 
ATOM   2613 C  CD1 . TRP A 1 334 ? 139.536 149.483 138.355 1.00 79.75  ? 334 TRP A CD1 1 
ATOM   2614 C  CD2 . TRP A 1 334 ? 138.326 151.263 138.960 1.00 79.36  ? 334 TRP A CD2 1 
ATOM   2615 N  NE1 . TRP A 1 334 ? 140.404 150.450 138.790 1.00 81.88  ? 334 TRP A NE1 1 
ATOM   2616 C  CE2 . TRP A 1 334 ? 139.687 151.553 139.168 1.00 80.56  ? 334 TRP A CE2 1 
ATOM   2617 C  CE3 . TRP A 1 334 ? 137.374 152.236 139.273 1.00 76.12  ? 334 TRP A CE3 1 
ATOM   2618 C  CZ2 . TRP A 1 334 ? 140.120 152.775 139.672 1.00 80.34  ? 334 TRP A CZ2 1 
ATOM   2619 C  CZ3 . TRP A 1 334 ? 137.805 153.447 139.771 1.00 78.28  ? 334 TRP A CZ3 1 
ATOM   2620 C  CH2 . TRP A 1 334 ? 139.165 153.706 139.967 1.00 80.83  ? 334 TRP A CH2 1 
ATOM   2621 N  N   . HIS A 1 335 ? 135.214 147.050 136.463 1.00 62.50  ? 335 HIS A N   1 
ATOM   2622 C  CA  . HIS A 1 335 ? 133.999 146.248 136.413 1.00 57.51  ? 335 HIS A CA  1 
ATOM   2623 C  C   . HIS A 1 335 ? 134.307 144.758 136.315 1.00 62.98  ? 335 HIS A C   1 
ATOM   2624 O  O   . HIS A 1 335 ? 133.659 143.948 136.987 1.00 67.71  ? 335 HIS A O   1 
ATOM   2625 C  CB  . HIS A 1 335 ? 133.141 146.704 135.234 1.00 57.70  ? 335 HIS A CB  1 
ATOM   2626 C  CG  . HIS A 1 335 ? 131.876 145.929 135.071 1.00 58.78  ? 335 HIS A CG  1 
ATOM   2627 N  ND1 . HIS A 1 335 ? 130.966 145.769 136.093 1.00 71.38  ? 335 HIS A ND1 1 
ATOM   2628 C  CD2 . HIS A 1 335 ? 131.363 145.276 134.003 1.00 61.54  ? 335 HIS A CD2 1 
ATOM   2629 C  CE1 . HIS A 1 335 ? 129.948 145.048 135.662 1.00 64.16  ? 335 HIS A CE1 1 
ATOM   2630 N  NE2 . HIS A 1 335 ? 130.164 144.735 134.398 1.00 56.30  ? 335 HIS A NE2 1 
ATOM   2631 N  N   . ILE A 1 336 ? 135.225 144.386 135.423 1.00 62.66  ? 336 ILE A N   1 
ATOM   2632 C  CA  . ILE A 1 336 ? 135.720 142.988 135.266 1.00 55.75  ? 336 ILE A CA  1 
ATOM   2633 C  C   . ILE A 1 336 ? 136.499 142.479 136.501 1.00 63.05  ? 336 ILE A C   1 
ATOM   2634 O  O   . ILE A 1 336 ? 136.210 141.357 136.885 1.00 76.59  ? 336 ILE A O   1 
ATOM   2635 C  CB  . ILE A 1 336 ? 136.469 142.832 133.912 1.00 54.33  ? 336 ILE A CB  1 
ATOM   2636 C  CG1 . ILE A 1 336 ? 135.499 142.479 132.779 1.00 58.35  ? 336 ILE A CG1 1 
ATOM   2637 C  CG2 . ILE A 1 336 ? 137.604 141.828 134.001 1.00 60.87  ? 336 ILE A CG2 1 
ATOM   2638 C  CD1 . ILE A 1 336 ? 134.870 143.662 132.086 1.00 67.79  ? 336 ILE A CD1 1 
ATOM   2639 N  N   . GLN A 1 337 ? 137.334 143.304 137.165 1.00 65.16  ? 337 GLN A N   1 
ATOM   2640 C  CA  . GLN A 1 337 ? 138.126 142.896 138.317 1.00 70.10  ? 337 GLN A CA  1 
ATOM   2641 C  C   . GLN A 1 337 ? 137.260 142.734 139.561 1.00 76.03  ? 337 GLN A C   1 
ATOM   2642 O  O   . GLN A 1 337 ? 137.470 141.804 140.344 1.00 77.75  ? 337 GLN A O   1 
ATOM   2643 C  CB  . GLN A 1 337 ? 139.244 143.906 138.569 1.00 77.64  ? 337 GLN A CB  1 
ATOM   2644 C  CG  . GLN A 1 337 ? 140.335 143.907 137.510 1.00 74.52  ? 337 GLN A CG  1 
ATOM   2645 C  CD  . GLN A 1 337 ? 140.961 142.542 137.309 1.00 80.97  ? 337 GLN A CD  1 
ATOM   2646 O  OE1 . GLN A 1 337 ? 141.311 141.859 138.269 1.00 88.63  ? 337 GLN A OE1 1 
ATOM   2647 N  NE2 . GLN A 1 337 ? 141.102 142.138 136.056 1.00 78.86  ? 337 GLN A NE2 1 
ATOM   2648 N  N   . SER A 1 338 ? 136.289 143.629 139.762 1.00 76.12  ? 338 SER A N   1 
ATOM   2649 C  CA  . SER A 1 338 ? 135.430 143.536 140.935 1.00 64.81  ? 338 SER A CA  1 
ATOM   2650 C  C   . SER A 1 338 ? 134.574 142.279 140.897 1.00 69.58  ? 338 SER A C   1 
ATOM   2651 O  O   . SER A 1 338 ? 134.344 141.648 141.933 1.00 90.20  ? 338 SER A O   1 
ATOM   2652 C  CB  . SER A 1 338 ? 134.552 144.781 141.041 1.00 75.47  ? 338 SER A CB  1 
ATOM   2653 O  OG  . SER A 1 338 ? 135.303 145.954 140.794 1.00 91.01  ? 338 SER A OG  1 
ATOM   2654 N  N   . ALA A 1 339 ? 134.077 141.911 139.714 1.00 61.32  ? 339 ALA A N   1 
ATOM   2655 C  CA  . ALA A 1 339 ? 133.320 140.671 139.587 1.00 69.71  ? 339 ALA A CA  1 
ATOM   2656 C  C   . ALA A 1 339 ? 134.169 139.478 139.999 1.00 65.82  ? 339 ALA A C   1 
ATOM   2657 O  O   . ALA A 1 339 ? 133.746 138.645 140.818 1.00 78.58  ? 339 ALA A O   1 
ATOM   2658 C  CB  . ALA A 1 339 ? 132.821 140.502 138.153 1.00 62.00  ? 339 ALA A CB  1 
ATOM   2659 N  N   . ILE A 1 340 ? 135.356 139.315 139.425 1.00 58.53  ? 340 ILE A N   1 
ATOM   2660 C  CA  . ILE A 1 340 ? 136.314 138.248 139.825 1.00 63.98  ? 340 ILE A CA  1 
ATOM   2661 C  C   . ILE A 1 340 ? 136.576 138.283 141.338 1.00 73.13  ? 340 ILE A C   1 
ATOM   2662 O  O   . ILE A 1 340 ? 136.448 137.232 141.961 1.00 73.17  ? 340 ILE A O   1 
ATOM   2663 C  CB  . ILE A 1 340 ? 137.632 138.326 139.027 1.00 70.82  ? 340 ILE A CB  1 
ATOM   2664 C  CG1 . ILE A 1 340 ? 137.450 138.066 137.527 1.00 74.40  ? 340 ILE A CG1 1 
ATOM   2665 C  CG2 . ILE A 1 340 ? 138.689 137.402 139.617 1.00 66.05  ? 340 ILE A CG2 1 
ATOM   2666 C  CD1 . ILE A 1 340 ? 138.581 138.607 136.678 1.00 74.21  ? 340 ILE A CD1 1 
ATOM   2667 N  N   . PHE A 1 341 ? 136.815 139.466 141.887 1.00 77.59  ? 341 PHE A N   1 
ATOM   2668 C  CA  . PHE A 1 341 ? 137.166 139.560 143.298 1.00 62.54  ? 341 PHE A CA  1 
ATOM   2669 C  C   . PHE A 1 341 ? 136.016 139.134 144.199 1.00 69.82  ? 341 PHE A C   1 
ATOM   2670 O  O   . PHE A 1 341 ? 136.225 138.389 145.159 1.00 83.18  ? 341 PHE A O   1 
ATOM   2671 C  CB  . PHE A 1 341 ? 137.603 140.984 143.640 1.00 67.29  ? 341 PHE A CB  1 
ATOM   2672 C  CG  . PHE A 1 341 ? 139.016 141.296 143.245 1.00 77.88  ? 341 PHE A CG  1 
ATOM   2673 C  CD1 . PHE A 1 341 ? 140.024 140.370 143.445 1.00 77.74  ? 341 PHE A CD1 1 
ATOM   2674 C  CD2 . PHE A 1 341 ? 139.339 142.520 142.685 1.00 79.55  ? 341 PHE A CD2 1 
ATOM   2675 C  CE1 . PHE A 1 341 ? 141.326 140.657 143.086 1.00 82.99  ? 341 PHE A CE1 1 
ATOM   2676 C  CE2 . PHE A 1 341 ? 140.637 142.811 142.324 1.00 73.99  ? 341 PHE A CE2 1 
ATOM   2677 C  CZ  . PHE A 1 341 ? 141.632 141.878 142.526 1.00 77.74  ? 341 PHE A CZ  1 
ATOM   2678 N  N   . TRP A 1 342 ? 134.795 139.589 143.913 1.00 65.66  ? 342 TRP A N   1 
ATOM   2679 C  CA  . TRP A 1 342 ? 133.709 139.285 144.837 1.00 59.39  ? 342 TRP A CA  1 
ATOM   2680 C  C   . TRP A 1 342 ? 133.221 137.849 144.696 1.00 67.21  ? 342 TRP A C   1 
ATOM   2681 O  O   . TRP A 1 342 ? 132.860 137.229 145.704 1.00 75.67  ? 342 TRP A O   1 
ATOM   2682 C  CB  . TRP A 1 342 ? 132.566 140.302 144.693 1.00 62.68  ? 342 TRP A CB  1 
ATOM   2683 C  CG  . TRP A 1 342 ? 131.561 140.087 143.599 1.00 63.13  ? 342 TRP A CG  1 
ATOM   2684 C  CD1 . TRP A 1 342 ? 131.513 140.735 142.403 1.00 63.94  ? 342 TRP A CD1 1 
ATOM   2685 C  CD2 . TRP A 1 342 ? 130.422 139.218 143.628 1.00 72.58  ? 342 TRP A CD2 1 
ATOM   2686 N  NE1 . TRP A 1 342 ? 130.439 140.301 141.670 1.00 62.61  ? 342 TRP A NE1 1 
ATOM   2687 C  CE2 . TRP A 1 342 ? 129.751 139.370 142.400 1.00 62.85  ? 342 TRP A CE2 1 
ATOM   2688 C  CE3 . TRP A 1 342 ? 129.915 138.315 144.566 1.00 78.51  ? 342 TRP A CE3 1 
ATOM   2689 C  CZ2 . TRP A 1 342 ? 128.602 138.654 142.087 1.00 60.43  ? 342 TRP A CZ2 1 
ATOM   2690 C  CZ3 . TRP A 1 342 ? 128.776 137.606 144.250 1.00 76.96  ? 342 TRP A CZ3 1 
ATOM   2691 C  CH2 . TRP A 1 342 ? 128.129 137.781 143.024 1.00 72.12  ? 342 TRP A CH2 1 
ATOM   2692 N  N   . ILE A 1 343 ? 133.250 137.275 143.490 1.00 68.48  ? 343 ILE A N   1 
ATOM   2693 C  CA  . ILE A 1 343 ? 132.931 135.853 143.371 1.00 64.81  ? 343 ILE A CA  1 
ATOM   2694 C  C   . ILE A 1 343 ? 133.961 135.011 144.125 1.00 76.16  ? 343 ILE A C   1 
ATOM   2695 O  O   . ILE A 1 343 ? 133.612 134.092 144.885 1.00 82.49  ? 343 ILE A O   1 
ATOM   2696 C  CB  . ILE A 1 343 ? 132.826 135.447 141.892 1.00 61.15  ? 343 ILE A CB  1 
ATOM   2697 C  CG1 . ILE A 1 343 ? 131.542 136.013 141.282 1.00 65.21  ? 343 ILE A CG1 1 
ATOM   2698 C  CG2 . ILE A 1 343 ? 132.856 133.937 141.749 1.00 66.42  ? 343 ILE A CG2 1 
ATOM   2699 C  CD1 . ILE A 1 343 ? 131.472 135.897 139.779 1.00 73.96  ? 343 ILE A CD1 1 
ATOM   2700 N  N   . ALA A 1 344 ? 135.247 135.330 143.945 1.00 71.52  ? 344 ALA A N   1 
ATOM   2701 C  CA  . ALA A 1 344 ? 136.292 134.592 144.646 1.00 67.29  ? 344 ALA A CA  1 
ATOM   2702 C  C   . ALA A 1 344 ? 136.170 134.762 146.154 1.00 76.28  ? 344 ALA A C   1 
ATOM   2703 O  O   . ALA A 1 344 ? 136.381 133.809 146.910 1.00 81.45  ? 344 ALA A O   1 
ATOM   2704 C  CB  . ALA A 1 344 ? 137.669 135.043 144.163 1.00 73.03  ? 344 ALA A CB  1 
ATOM   2705 N  N   . THR A 1 345 ? 135.856 135.953 146.613 1.00 73.72  ? 345 THR A N   1 
ATOM   2706 C  CA  . THR A 1 345 ? 135.673 136.241 148.058 1.00 66.48  ? 345 THR A CA  1 
ATOM   2707 C  C   . THR A 1 345 ? 134.518 135.402 148.610 1.00 73.88  ? 345 THR A C   1 
ATOM   2708 O  O   . THR A 1 345 ? 134.692 134.883 149.687 1.00 77.91  ? 345 THR A O   1 
ATOM   2709 C  CB  . THR A 1 345 ? 135.595 137.759 148.349 1.00 65.64  ? 345 THR A CB  1 
ATOM   2710 O  OG1 . THR A 1 345 ? 136.809 138.350 147.903 1.00 78.21  ? 345 THR A OG1 1 
ATOM   2711 C  CG2 . THR A 1 345 ? 135.364 138.072 149.812 1.00 70.81  ? 345 THR A CG2 1 
ATOM   2712 N  N   . GLY A 1 346 ? 133.410 135.321 147.884 1.00 75.23  ? 346 GLY A N   1 
ATOM   2713 C  CA  . GLY A 1 346 ? 132.305 134.495 148.346 1.00 72.18  ? 346 GLY A CA  1 
ATOM   2714 C  C   . GLY A 1 346 ? 132.699 133.038 148.497 1.00 78.71  ? 346 GLY A C   1 
ATOM   2715 O  O   . GLY A 1 346 ? 132.402 132.397 149.513 1.00 92.07  ? 346 GLY A O   1 
ATOM   2716 N  N   . PHE A 1 347 ? 133.393 132.496 147.491 1.00 73.86  ? 347 PHE A N   1 
ATOM   2717 C  CA  . PHE A 1 347 ? 133.850 131.111 147.599 1.00 76.33  ? 347 PHE A CA  1 
ATOM   2718 C  C   . PHE A 1 347 ? 134.807 130.934 148.775 1.00 83.38  ? 347 PHE A C   1 
ATOM   2719 O  O   . PHE A 1 347 ? 134.705 129.957 149.536 1.00 86.61  ? 347 PHE A O   1 
ATOM   2720 C  CB  . PHE A 1 347 ? 134.507 130.674 146.292 1.00 77.86  ? 347 PHE A CB  1 
ATOM   2721 C  CG  . PHE A 1 347 ? 133.537 130.146 145.276 1.00 82.90  ? 347 PHE A CG  1 
ATOM   2722 C  CD1 . PHE A 1 347 ? 132.679 131.004 144.607 1.00 89.29  ? 347 PHE A CD1 1 
ATOM   2723 C  CD2 . PHE A 1 347 ? 133.482 128.795 144.988 1.00 86.98  ? 347 PHE A CD2 1 
ATOM   2724 C  CE1 . PHE A 1 347 ? 131.786 130.522 143.674 1.00 86.98  ? 347 PHE A CE1 1 
ATOM   2725 C  CE2 . PHE A 1 347 ? 132.590 128.308 144.054 1.00 88.97  ? 347 PHE A CE2 1 
ATOM   2726 C  CZ  . PHE A 1 347 ? 131.742 129.174 143.397 1.00 87.77  ? 347 PHE A CZ  1 
ATOM   2727 N  N   . LEU A 1 348 ? 135.730 131.853 148.946 1.00 78.83  ? 348 LEU A N   1 
ATOM   2728 C  CA  . LEU A 1 348 ? 136.743 131.725 150.020 1.00 72.93  ? 348 LEU A CA  1 
ATOM   2729 C  C   . LEU A 1 348 ? 136.081 131.822 151.398 1.00 79.68  ? 348 LEU A C   1 
ATOM   2730 O  O   . LEU A 1 348 ? 136.438 131.029 152.212 1.00 90.22  ? 348 LEU A O   1 
ATOM   2731 C  CB  . LEU A 1 348 ? 137.862 132.753 149.838 1.00 76.39  ? 348 LEU A CB  1 
ATOM   2732 C  CG  . LEU A 1 348 ? 138.732 132.640 148.590 1.00 82.11  ? 348 LEU A CG  1 
ATOM   2733 C  CD1 . LEU A 1 348 ? 139.692 133.809 148.522 1.00 80.82  ? 348 LEU A CD1 1 
ATOM   2734 C  CD2 . LEU A 1 348 ? 139.487 131.323 148.523 1.00 80.92  ? 348 LEU A CD2 1 
ATOM   2735 N  N   . THR A 1 349 ? 135.009 132.590 151.566 1.00 72.46  ? 349 THR A N   1 
ATOM   2736 C  CA  . THR A 1 349 ? 134.340 132.796 152.858 1.00 73.13  ? 349 THR A CA  1 
ATOM   2737 C  C   . THR A 1 349 ? 133.627 131.481 153.144 1.00 76.57  ? 349 THR A C   1 
ATOM   2738 O  O   . THR A 1 349 ? 133.671 131.008 154.246 1.00 90.74  ? 349 THR A O   1 
ATOM   2739 C  CB  . THR A 1 349 ? 133.508 134.108 152.838 1.00 80.44  ? 349 THR A CB  1 
ATOM   2740 O  OG1 . THR A 1 349 ? 132.499 134.092 153.849 1.00 89.48  ? 349 THR A OG1 1 
ATOM   2741 C  CG2 . THR A 1 349 ? 132.809 134.383 151.538 1.00 76.83  ? 349 THR A CG2 1 
ATOM   2742 N  N   . ALA A 1 350 ? 132.934 131.019 152.133 1.00 64.30  ? 350 ALA A N   1 
ATOM   2743 C  CA  . ALA A 1 350 ? 132.209 129.768 152.329 1.00 70.14  ? 350 ALA A CA  1 
ATOM   2744 C  C   . ALA A 1 350 ? 133.147 128.669 152.812 1.00 73.78  ? 350 ALA A C   1 
ATOM   2745 O  O   . ALA A 1 350 ? 132.855 127.960 153.787 1.00 80.10  ? 350 ALA A O   1 
ATOM   2746 C  CB  . ALA A 1 350 ? 131.510 129.355 151.034 1.00 68.88  ? 350 ALA A CB  1 
ATOM   2747 N  N   . GLY A 1 351 ? 134.302 128.533 152.156 1.00 65.18  ? 351 GLY A N   1 
ATOM   2748 C  CA  . GLY A 1 351 ? 135.267 127.534 152.591 1.00 63.27  ? 351 GLY A CA  1 
ATOM   2749 C  C   . GLY A 1 351 ? 135.779 127.783 153.997 1.00 65.50  ? 351 GLY A C   1 
ATOM   2750 O  O   . GLY A 1 351 ? 135.928 126.848 154.793 1.00 77.92  ? 351 GLY A O   1 
ATOM   2751 N  N   . LEU A 1 352 ? 136.075 129.044 154.319 1.00 69.91  ? 352 LEU A N   1 
ATOM   2752 C  CA  . LEU A 1 352 ? 136.607 129.372 155.637 1.00 67.78  ? 352 LEU A CA  1 
ATOM   2753 C  C   . LEU A 1 352 ? 135.587 129.088 156.729 1.00 68.64  ? 352 LEU A C   1 
ATOM   2754 O  O   . LEU A 1 352 ? 135.957 128.681 157.835 1.00 67.24  ? 352 LEU A O   1 
ATOM   2755 C  CB  . LEU A 1 352 ? 137.046 130.834 155.681 1.00 69.95  ? 352 LEU A CB  1 
ATOM   2756 C  CG  . LEU A 1 352 ? 138.461 131.132 155.187 1.00 68.03  ? 352 LEU A CG  1 
ATOM   2757 C  CD1 . LEU A 1 352 ? 138.728 132.625 155.227 1.00 71.22  ? 352 LEU A CD1 1 
ATOM   2758 C  CD2 . LEU A 1 352 ? 139.498 130.368 155.994 1.00 73.29  ? 352 LEU A CD2 1 
ATOM   2759 N  N   . PHE A 1 353 ? 134.302 129.320 156.451 1.00 76.75  ? 353 PHE A N   1 
ATOM   2760 C  CA  . PHE A 1 353 ? 133.275 128.926 157.408 1.00 73.64  ? 353 PHE A CA  1 
ATOM   2761 C  C   . PHE A 1 353 ? 133.218 127.414 157.557 1.00 78.78  ? 353 PHE A C   1 
ATOM   2762 O  O   . PHE A 1 353 ? 133.036 126.901 158.667 1.00 85.20  ? 353 PHE A O   1 
ATOM   2763 C  CB  . PHE A 1 353 ? 131.910 129.467 156.985 1.00 75.62  ? 353 PHE A CB  1 
ATOM   2764 C  CG  . PHE A 1 353 ? 130.816 129.178 157.973 1.00 77.95  ? 353 PHE A CG  1 
ATOM   2765 C  CD1 . PHE A 1 353 ? 130.601 130.014 159.053 1.00 82.52  ? 353 PHE A CD1 1 
ATOM   2766 C  CD2 . PHE A 1 353 ? 130.011 128.060 157.831 1.00 77.47  ? 353 PHE A CD2 1 
ATOM   2767 C  CE1 . PHE A 1 353 ? 129.603 129.748 159.965 1.00 76.90  ? 353 PHE A CE1 1 
ATOM   2768 C  CE2 . PHE A 1 353 ? 129.012 127.790 158.743 1.00 80.79  ? 353 PHE A CE2 1 
ATOM   2769 C  CZ  . PHE A 1 353 ? 128.808 128.634 159.810 1.00 78.67  ? 353 PHE A CZ  1 
ATOM   2770 N  N   . LEU A 1 354 ? 133.396 126.597 156.546 1.00 82.33  ? 354 LEU A N   1 
ATOM   2771 C  CA  . LEU A 1 354 ? 133.241 125.143 156.728 1.00 76.79  ? 354 LEU A CA  1 
ATOM   2772 C  C   . LEU A 1 354 ? 134.488 124.528 157.362 1.00 75.50  ? 354 LEU A C   1 
ATOM   2773 O  O   . LEU A 1 354 ? 134.405 123.484 157.946 1.00 78.16  ? 354 LEU A O   1 
ATOM   2774 C  CB  . LEU A 1 354 ? 132.894 124.509 155.375 1.00 74.48  ? 354 LEU A CB  1 
ATOM   2775 C  CG  . LEU A 1 354 ? 131.490 124.757 154.845 1.00 80.01  ? 354 LEU A CG  1 
ATOM   2776 C  CD1 . LEU A 1 354 ? 131.337 124.153 153.460 1.00 80.83  ? 354 LEU A CD1 1 
ATOM   2777 C  CD2 . LEU A 1 354 ? 130.448 124.212 155.803 1.00 77.85  ? 354 LEU A CD2 1 
ATOM   2778 N  N   . ALA A 1 355 ? 135.608 125.198 157.231 1.00 82.95  ? 355 ALA A N   1 
ATOM   2779 C  CA  . ALA A 1 355 ? 136.801 124.534 157.761 1.00 77.39  ? 355 ALA A CA  1 
ATOM   2780 C  C   . ALA A 1 355 ? 136.713 124.164 159.244 1.00 86.17  ? 355 ALA A C   1 
ATOM   2781 O  O   . ALA A 1 355 ? 137.033 123.010 159.584 1.00 96.84  ? 355 ALA A O   1 
ATOM   2782 C  CB  . ALA A 1 355 ? 138.034 125.399 157.478 1.00 82.31  ? 355 ALA A CB  1 
ATOM   2783 N  N   . PRO A 1 356 ? 136.331 125.057 160.167 1.00 83.94  ? 356 PRO A N   1 
ATOM   2784 C  CA  . PRO A 1 356 ? 136.256 124.637 161.578 1.00 81.45  ? 356 PRO A CA  1 
ATOM   2785 C  C   . PRO A 1 356 ? 135.253 123.527 161.828 1.00 90.03  ? 356 PRO A C   1 
ATOM   2786 O  O   . PRO A 1 356 ? 135.433 122.740 162.765 1.00 95.38  ? 356 PRO A O   1 
ATOM   2787 C  CB  . PRO A 1 356 ? 135.868 125.928 162.313 1.00 82.57  ? 356 PRO A CB  1 
ATOM   2788 C  CG  . PRO A 1 356 ? 136.263 127.018 161.399 1.00 87.79  ? 356 PRO A CG  1 
ATOM   2789 C  CD  . PRO A 1 356 ? 136.023 126.490 160.027 1.00 88.46  ? 356 PRO A CD  1 
ATOM   2790 N  N   . ILE A 1 357 ? 134.189 123.447 161.025 1.00 94.67  ? 357 ILE A N   1 
ATOM   2791 C  CA  . ILE A 1 357 ? 133.260 122.328 161.131 1.00 92.18  ? 357 ILE A CA  1 
ATOM   2792 C  C   . ILE A 1 357 ? 133.963 121.022 160.795 1.00 91.94  ? 357 ILE A C   1 
ATOM   2793 O  O   . ILE A 1 357 ? 133.757 120.002 161.467 1.00 92.06  ? 357 ILE A O   1 
ATOM   2794 C  CB  . ILE A 1 357 ? 132.036 122.567 160.226 1.00 88.32  ? 357 ILE A CB  1 
ATOM   2795 C  CG1 . ILE A 1 357 ? 131.188 123.712 160.774 1.00 94.36  ? 357 ILE A CG1 1 
ATOM   2796 C  CG2 . ILE A 1 357 ? 131.203 121.302 160.103 1.00 89.21  ? 357 ILE A CG2 1 
ATOM   2797 C  CD1 . ILE A 1 357 ? 130.093 124.156 159.839 1.00 96.40  ? 357 ILE A CD1 1 
ATOM   2798 N  N   . VAL A 1 358 ? 134.801 121.025 159.756 1.00 88.30  ? 358 VAL A N   1 
ATOM   2799 C  CA  . VAL A 1 358 ? 135.613 119.853 159.449 1.00 83.93  ? 358 VAL A CA  1 
ATOM   2800 C  C   . VAL A 1 358 ? 136.539 119.530 160.611 1.00 86.97  ? 358 VAL A C   1 
ATOM   2801 O  O   . VAL A 1 358 ? 136.732 118.358 160.955 1.00 90.47  ? 358 VAL A O   1 
ATOM   2802 C  CB  . VAL A 1 358 ? 136.406 120.077 158.149 1.00 82.71  ? 358 VAL A CB  1 
ATOM   2803 C  CG1 . VAL A 1 358 ? 137.324 118.897 157.871 1.00 83.37  ? 358 VAL A CG1 1 
ATOM   2804 C  CG2 . VAL A 1 358 ? 135.467 120.318 156.984 1.00 91.51  ? 358 VAL A CG2 1 
ATOM   2805 N  N   . ASN A 1 359 ? 137.113 120.552 161.243 1.00 93.51  ? 359 ASN A N   1 
ATOM   2806 C  CA  . ASN A 1 359 ? 138.007 120.346 162.377 1.00 94.54  ? 359 ASN A CA  1 
ATOM   2807 C  C   . ASN A 1 359 ? 137.276 119.917 163.648 1.00 91.79  ? 359 ASN A C   1 
ATOM   2808 O  O   . ASN A 1 359 ? 137.897 119.863 164.714 1.00 92.73  ? 359 ASN A O   1 
ATOM   2809 C  CB  . ASN A 1 359 ? 138.814 121.619 162.650 1.00 94.03  ? 359 ASN A CB  1 
ATOM   2810 C  CG  . ASN A 1 359 ? 140.079 121.349 163.440 1.00 93.65  ? 359 ASN A CG  1 
ATOM   2811 O  OD1 . ASN A 1 359 ? 140.848 120.448 163.116 1.00 94.26  ? 359 ASN A OD1 1 
ATOM   2812 N  ND2 . ASN A 1 359 ? 140.297 122.130 164.490 1.00 97.58  ? 359 ASN A ND2 1 
ATOM   2813 N  N   . GLY A 1 360 ? 135.985 119.608 163.569 1.00 93.75  ? 360 GLY A N   1 
ATOM   2814 C  CA  . GLY A 1 360 ? 135.245 119.207 164.746 1.00 93.08  ? 360 GLY A CA  1 
ATOM   2815 C  C   . GLY A 1 360 ? 134.713 120.344 165.583 1.00 95.58  ? 360 GLY A C   1 
ATOM   2816 O  O   . GLY A 1 360 ? 134.448 120.150 166.772 1.00 96.48  ? 360 GLY A O   1 
ATOM   2817 N  N   . GLY A 1 361 ? 134.550 121.529 165.001 1.00 104.67 ? 361 GLY A N   1 
ATOM   2818 C  CA  . GLY A 1 361 ? 134.042 122.664 165.743 1.00 104.80 ? 361 GLY A CA  1 
ATOM   2819 C  C   . GLY A 1 361 ? 135.051 123.360 166.624 1.00 103.93 ? 361 GLY A C   1 
ATOM   2820 O  O   . GLY A 1 361 ? 134.659 124.017 167.592 1.00 104.53 ? 361 GLY A O   1 
ATOM   2821 N  N   . LYS A 1 362 ? 136.341 123.234 166.327 1.00 105.11 ? 362 LYS A N   1 
ATOM   2822 C  CA  . LYS A 1 362 ? 137.386 123.876 167.109 1.00 105.10 ? 362 LYS A CA  1 
ATOM   2823 C  C   . LYS A 1 362 ? 138.356 124.600 166.188 1.00 103.92 ? 362 LYS A C   1 
ATOM   2824 O  O   . LYS A 1 362 ? 138.608 124.171 165.059 1.00 106.59 ? 362 LYS A O   1 
ATOM   2825 C  CB  . LYS A 1 362 ? 138.150 122.862 167.971 1.00 104.58 ? 362 LYS A CB  1 
ATOM   2826 C  CG  . LYS A 1 362 ? 137.320 122.237 169.083 1.00 110.44 ? 362 LYS A CG  1 
ATOM   2827 C  CD  . LYS A 1 362 ? 138.111 121.216 169.901 1.00 110.40 ? 362 LYS A CD  1 
ATOM   2828 C  CE  . LYS A 1 362 ? 137.288 120.608 171.027 1.00 110.43 ? 362 LYS A CE  1 
ATOM   2829 N  NZ  . LYS A 1 362 ? 138.067 119.599 171.797 1.00 109.60 ? 362 LYS A NZ  1 
ATOM   2830 N  N   . ASP A 1 363 ? 138.893 125.702 166.683 1.00 109.12 ? 363 ASP A N   1 
ATOM   2831 C  CA  . ASP A 1 363 ? 139.906 126.486 165.992 1.00 113.65 ? 363 ASP A CA  1 
ATOM   2832 C  C   . ASP A 1 363 ? 141.279 125.921 166.300 1.00 116.69 ? 363 ASP A C   1 
ATOM   2833 O  O   . ASP A 1 363 ? 141.628 125.791 167.482 1.00 119.49 ? 363 ASP A O   1 
ATOM   2834 C  CB  . ASP A 1 363 ? 139.838 127.942 166.442 1.00 115.67 ? 363 ASP A CB  1 
ATOM   2835 C  CG  . ASP A 1 363 ? 139.002 128.797 165.519 1.00 119.64 ? 363 ASP A CG  1 
ATOM   2836 O  OD1 . ASP A 1 363 ? 138.464 128.263 164.528 1.00 120.70 ? 363 ASP A OD1 1 
ATOM   2837 O  OD2 . ASP A 1 363 ? 138.867 130.004 165.797 1.00 119.54 ? 363 ASP A OD2 1 
ATOM   2838 N  N   . PRO A 1 364 ? 142.056 125.664 165.214 1.00 107.58 ? 364 PRO A N   1 
ATOM   2839 C  CA  . PRO A 1 364 ? 143.473 125.410 165.353 1.00 107.25 ? 364 PRO A CA  1 
ATOM   2840 C  C   . PRO A 1 364 ? 144.057 126.763 165.825 1.00 108.85 ? 364 PRO A C   1 
ATOM   2841 O  O   . PRO A 1 364 ? 143.532 127.759 165.473 1.00 110.02 ? 364 PRO A O   1 
ATOM   2842 C  CB  . PRO A 1 364 ? 143.853 125.044 163.913 1.00 101.76 ? 364 PRO A CB  1 
ATOM   2843 C  CG  . PRO A 1 364 ? 142.599 124.661 163.218 1.00 103.61 ? 364 PRO A CG  1 
ATOM   2844 C  CD  . PRO A 1 364 ? 141.596 125.599 163.824 1.00 101.99 ? 364 PRO A CD  1 
ATOM   2845 N  N   . LYS A 1 365 ? 145.124 126.772 166.619 1.00 105.92 ? 365 LYS A N   1 
ATOM   2846 C  CA  . LYS A 1 365 ? 145.767 128.002 167.186 1.00 103.01 ? 365 LYS A CA  1 
ATOM   2847 C  C   . LYS A 1 365 ? 146.094 129.070 166.160 1.00 108.98 ? 365 LYS A C   1 
ATOM   2848 O  O   . LYS A 1 365 ? 146.836 128.754 165.250 1.00 111.36 ? 365 LYS A O   1 
ATOM   2849 C  CB  . LYS A 1 365 ? 147.097 127.747 167.894 1.00 102.71 ? 365 LYS A CB  1 
ATOM   2850 C  CG  . LYS A 1 365 ? 147.510 128.787 168.919 1.00 102.46 ? 365 LYS A CG  1 
ATOM   2851 C  CD  . LYS A 1 365 ? 148.874 128.521 169.507 1.00 107.35 ? 365 LYS A CD  1 
ATOM   2852 C  CE  . LYS A 1 365 ? 148.917 128.736 171.006 1.00 108.70 ? 365 LYS A CE  1 
ATOM   2853 N  NZ  . LYS A 1 365 ? 150.304 128.913 171.489 1.00 108.54 ? 365 LYS A NZ  1 
ATOM   2854 N  N   . PHE A 1 366 ? 145.531 130.269 166.316 1.00 107.59 ? 366 PHE A N   1 
ATOM   2855 C  CA  . PHE A 1 366 ? 145.798 131.461 165.465 1.00 104.45 ? 366 PHE A CA  1 
ATOM   2856 C  C   . PHE A 1 366 ? 144.909 131.505 164.221 1.00 104.62 ? 366 PHE A C   1 
ATOM   2857 O  O   . PHE A 1 366 ? 145.297 132.165 163.299 1.00 109.44 ? 366 PHE A O   1 
ATOM   2858 C  CB  . PHE A 1 366 ? 147.300 131.625 165.197 1.00 102.34 ? 366 PHE A CB  1 
ATOM   2859 C  CG  . PHE A 1 366 ? 148.196 131.784 166.395 1.00 106.83 ? 366 PHE A CG  1 
ATOM   2860 C  CD1 . PHE A 1 366 ? 147.893 132.685 167.398 1.00 108.36 ? 366 PHE A CD1 1 
ATOM   2861 C  CD2 . PHE A 1 366 ? 149.356 131.040 166.502 1.00 105.81 ? 366 PHE A CD2 1 
ATOM   2862 C  CE1 . PHE A 1 366 ? 148.727 132.825 168.493 1.00 107.72 ? 366 PHE A CE1 1 
ATOM   2863 C  CE2 . PHE A 1 366 ? 150.188 131.178 167.598 1.00 104.82 ? 366 PHE A CE2 1 
ATOM   2864 C  CZ  . PHE A 1 366 ? 149.871 132.072 168.591 1.00 106.01 ? 366 PHE A CZ  1 
ATOM   2865 N  N   . GLN A 1 367 ? 143.756 130.855 164.239 1.00 95.34  ? 367 GLN A N   1 
ATOM   2866 C  CA  . GLN A 1 367 ? 142.942 130.817 163.030 1.00 89.59  ? 367 GLN A CA  1 
ATOM   2867 C  C   . GLN A 1 367 ? 142.242 132.149 162.798 1.00 95.92  ? 367 GLN A C   1 
ATOM   2868 O  O   . GLN A 1 367 ? 142.132 132.610 161.656 1.00 97.95  ? 367 GLN A O   1 
ATOM   2869 C  CB  . GLN A 1 367 ? 141.928 129.675 163.116 1.00 90.19  ? 367 GLN A CB  1 
ATOM   2870 C  CG  . GLN A 1 367 ? 141.170 129.431 161.825 1.00 95.60  ? 367 GLN A CG  1 
ATOM   2871 C  CD  . GLN A 1 367 ? 141.847 128.406 160.941 1.00 96.67  ? 367 GLN A CD  1 
ATOM   2872 O  OE1 . GLN A 1 367 ? 142.956 127.960 161.228 1.00 99.22  ? 367 GLN A OE1 1 
ATOM   2873 N  NE2 . GLN A 1 367 ? 141.188 128.034 159.853 1.00 95.49  ? 367 GLN A NE2 1 
ATOM   2874 N  N   . ARG A 1 368 ? 141.767 132.785 163.871 1.00 92.92  ? 368 ARG A N   1 
ATOM   2875 C  CA  . ARG A 1 368 ? 141.164 134.107 163.739 1.00 93.34  ? 368 ARG A CA  1 
ATOM   2876 C  C   . ARG A 1 368 ? 142.180 135.132 163.253 1.00 98.85  ? 368 ARG A C   1 
ATOM   2877 O  O   . ARG A 1 368 ? 141.866 135.981 162.407 1.00 104.28 ? 368 ARG A O   1 
ATOM   2878 C  CB  . ARG A 1 368 ? 140.561 134.537 165.074 1.00 89.76  ? 368 ARG A CB  1 
ATOM   2879 C  CG  . ARG A 1 368 ? 139.400 135.499 164.945 1.00 92.55  ? 368 ARG A CG  1 
ATOM   2880 C  CD  . ARG A 1 368 ? 139.526 136.643 165.930 1.00 95.43  ? 368 ARG A CD  1 
ATOM   2881 N  NE  . ARG A 1 368 ? 139.524 136.173 167.308 1.00 101.23 ? 368 ARG A NE  1 
ATOM   2882 C  CZ  . ARG A 1 368 ? 139.220 136.929 168.355 1.00 101.73 ? 368 ARG A CZ  1 
ATOM   2883 N  NH1 . ARG A 1 368 ? 138.878 138.198 168.212 1.00 98.02  ? 368 ARG A NH1 1 
ATOM   2884 N  NH2 . ARG A 1 368 ? 139.260 136.398 169.572 1.00 100.50 ? 368 ARG A NH2 1 
ATOM   2885 N  N   . ALA A 1 369 ? 143.406 135.069 163.775 1.00 95.45  ? 369 ALA A N   1 
ATOM   2886 C  CA  . ALA A 1 369 ? 144.455 135.972 163.315 1.00 94.43  ? 369 ALA A CA  1 
ATOM   2887 C  C   . ALA A 1 369 ? 144.758 135.756 161.840 1.00 94.35  ? 369 ALA A C   1 
ATOM   2888 O  O   . ALA A 1 369 ? 144.940 136.720 161.088 1.00 101.45 ? 369 ALA A O   1 
ATOM   2889 C  CB  . ALA A 1 369 ? 145.715 135.785 164.157 1.00 95.28  ? 369 ALA A CB  1 
ATOM   2890 N  N   . GLY A 1 370 ? 144.812 134.495 161.407 1.00 83.65  ? 370 GLY A N   1 
ATOM   2891 C  CA  . GLY A 1 370 ? 145.028 134.217 159.996 1.00 80.91  ? 370 GLY A CA  1 
ATOM   2892 C  C   . GLY A 1 370 ? 143.902 134.735 159.122 1.00 84.48  ? 370 GLY A C   1 
ATOM   2893 O  O   . GLY A 1 370 ? 144.141 135.268 158.036 1.00 94.95  ? 370 GLY A O   1 
ATOM   2894 N  N   . VAL A 1 371 ? 142.659 134.584 159.584 1.00 78.44  ? 371 VAL A N   1 
ATOM   2895 C  CA  . VAL A 1 371 ? 141.512 135.080 158.830 1.00 82.19  ? 371 VAL A CA  1 
ATOM   2896 C  C   . VAL A 1 371 ? 141.574 136.597 158.695 1.00 87.36  ? 371 VAL A C   1 
ATOM   2897 O  O   . VAL A 1 371 ? 141.333 137.154 157.617 1.00 92.71  ? 371 VAL A O   1 
ATOM   2898 C  CB  . VAL A 1 371 ? 140.204 134.614 159.497 1.00 79.02  ? 371 VAL A CB  1 
ATOM   2899 C  CG1 . VAL A 1 371 ? 139.028 135.450 159.031 1.00 81.81  ? 371 VAL A CG1 1 
ATOM   2900 C  CG2 . VAL A 1 371 ? 139.960 133.144 159.208 1.00 77.85  ? 371 VAL A CG2 1 
ATOM   2901 N  N   . ASN A 1 372 ? 141.910 137.290 159.787 1.00 88.36  ? 372 ASN A N   1 
ATOM   2902 C  CA  . ASN A 1 372 ? 142.023 138.745 159.735 1.00 82.61  ? 372 ASN A CA  1 
ATOM   2903 C  C   . ASN A 1 372 ? 143.161 139.184 158.819 1.00 85.94  ? 372 ASN A C   1 
ATOM   2904 O  O   . ASN A 1 372 ? 143.025 140.164 158.073 1.00 89.34  ? 372 ASN A O   1 
ATOM   2905 C  CB  . ASN A 1 372 ? 142.215 139.302 161.145 1.00 82.43  ? 372 ASN A CB  1 
ATOM   2906 C  CG  . ASN A 1 372 ? 141.001 139.088 162.024 1.00 91.59  ? 372 ASN A CG  1 
ATOM   2907 O  OD1 . ASN A 1 372 ? 139.897 138.872 161.531 1.00 92.35  ? 372 ASN A OD1 1 
ATOM   2908 N  ND2 . ASN A 1 372 ? 141.201 139.142 163.333 1.00 93.88  ? 372 ASN A ND2 1 
ATOM   2909 N  N   . PHE A 1 373 ? 144.290 138.474 158.862 1.00 88.59  ? 373 PHE A N   1 
ATOM   2910 C  CA  . PHE A 1 373 ? 145.404 138.791 157.974 1.00 83.63  ? 373 PHE A CA  1 
ATOM   2911 C  C   . PHE A 1 373 ? 145.014 138.604 156.515 1.00 87.40  ? 373 PHE A C   1 
ATOM   2912 O  O   . PHE A 1 373 ? 145.380 139.415 155.657 1.00 99.66  ? 373 PHE A O   1 
ATOM   2913 C  CB  . PHE A 1 373 ? 146.612 137.923 158.321 1.00 87.88  ? 373 PHE A CB  1 
ATOM   2914 C  CG  . PHE A 1 373 ? 147.309 138.331 159.586 1.00 98.81  ? 373 PHE A CG  1 
ATOM   2915 C  CD1 . PHE A 1 373 ? 147.013 139.534 160.202 1.00 99.87  ? 373 PHE A CD1 1 
ATOM   2916 C  CD2 . PHE A 1 373 ? 148.248 137.498 160.170 1.00 98.05  ? 373 PHE A CD2 1 
ATOM   2917 C  CE1 . PHE A 1 373 ? 147.650 139.905 161.370 1.00 100.11 ? 373 PHE A CE1 1 
ATOM   2918 C  CE2 . PHE A 1 373 ? 148.888 137.864 161.338 1.00 98.20  ? 373 PHE A CE2 1 
ATOM   2919 C  CZ  . PHE A 1 373 ? 148.589 139.070 161.939 1.00 101.64 ? 373 PHE A CZ  1 
ATOM   2920 N  N   . LEU A 1 374 ? 144.276 137.534 156.214 1.00 79.04  ? 374 LEU A N   1 
ATOM   2921 C  CA  . LEU A 1 374 ? 143.806 137.315 154.850 1.00 75.67  ? 374 LEU A CA  1 
ATOM   2922 C  C   . LEU A 1 374 ? 142.859 138.422 154.408 1.00 78.50  ? 374 LEU A C   1 
ATOM   2923 O  O   . LEU A 1 374 ? 142.911 138.875 153.257 1.00 90.78  ? 374 LEU A O   1 
ATOM   2924 C  CB  . LEU A 1 374 ? 143.128 135.951 154.744 1.00 72.80  ? 374 LEU A CB  1 
ATOM   2925 C  CG  . LEU A 1 374 ? 142.501 135.595 153.395 1.00 74.99  ? 374 LEU A CG  1 
ATOM   2926 C  CD1 . LEU A 1 374 ? 143.547 135.614 152.296 1.00 82.04  ? 374 LEU A CD1 1 
ATOM   2927 C  CD2 . LEU A 1 374 ? 141.821 134.242 153.466 1.00 79.57  ? 374 LEU A CD2 1 
ATOM   2928 N  N   . TYR A 1 375 ? 142.062 138.959 155.314 1.00 79.37  ? 375 TYR A N   1 
ATOM   2929 C  CA  . TYR A 1 375 ? 141.072 140.001 155.006 1.00 79.99  ? 375 TYR A CA  1 
ATOM   2930 C  C   . TYR A 1 375 ? 141.828 141.275 154.675 1.00 84.22  ? 375 TYR A C   1 
ATOM   2931 O  O   . TYR A 1 375 ? 141.397 141.979 153.765 1.00 90.50  ? 375 TYR A O   1 
ATOM   2932 C  CB  . TYR A 1 375 ? 140.090 140.219 156.164 1.00 84.45  ? 375 TYR A CB  1 
ATOM   2933 C  CG  . TYR A 1 375 ? 138.992 141.208 155.906 1.00 86.62  ? 375 TYR A CG  1 
ATOM   2934 C  CD1 . TYR A 1 375 ? 137.837 140.808 155.265 1.00 90.55  ? 375 TYR A CD1 1 
ATOM   2935 C  CD2 . TYR A 1 375 ? 139.118 142.531 156.298 1.00 86.73  ? 375 TYR A CD2 1 
ATOM   2936 C  CE1 . TYR A 1 375 ? 136.820 141.704 155.014 1.00 90.13  ? 375 TYR A CE1 1 
ATOM   2937 C  CE2 . TYR A 1 375 ? 138.107 143.439 156.059 1.00 91.64  ? 375 TYR A CE2 1 
ATOM   2938 C  CZ  . TYR A 1 375 ? 136.957 143.019 155.416 1.00 93.90  ? 375 TYR A CZ  1 
ATOM   2939 O  OH  . TYR A 1 375 ? 135.943 143.901 155.187 1.00 98.12  ? 375 TYR A OH  1 
ATOM   2940 N  N   . ILE A 1 376 ? 142.860 141.547 155.477 1.00 76.07  ? 376 ILE A N   1 
ATOM   2941 C  CA  . ILE A 1 376 ? 143.676 142.737 155.242 1.00 77.82  ? 376 ILE A CA  1 
ATOM   2942 C  C   . ILE A 1 376 ? 144.416 142.622 153.914 1.00 77.24  ? 376 ILE A C   1 
ATOM   2943 O  O   . ILE A 1 376 ? 144.516 143.593 153.154 1.00 80.07  ? 376 ILE A O   1 
ATOM   2944 C  CB  . ILE A 1 376 ? 144.645 142.954 156.418 1.00 80.87  ? 376 ILE A CB  1 
ATOM   2945 C  CG1 . ILE A 1 376 ? 143.907 143.571 157.606 1.00 82.75  ? 376 ILE A CG1 1 
ATOM   2946 C  CG2 . ILE A 1 376 ? 145.811 143.839 156.005 1.00 80.84  ? 376 ILE A CG2 1 
ATOM   2947 C  CD1 . ILE A 1 376 ? 144.669 143.475 158.905 1.00 86.05  ? 376 ILE A CD1 1 
ATOM   2948 N  N   . ALA A 1 377 ? 144.946 141.434 153.617 1.00 75.72  ? 377 ALA A N   1 
ATOM   2949 C  CA  . ALA A 1 377 ? 145.655 141.232 152.358 1.00 70.84  ? 377 ALA A CA  1 
ATOM   2950 C  C   . ALA A 1 377 ? 144.731 141.423 151.162 1.00 73.35  ? 377 ALA A C   1 
ATOM   2951 O  O   . ALA A 1 377 ? 145.120 142.033 150.161 1.00 88.73  ? 377 ALA A O   1 
ATOM   2952 C  CB  . ALA A 1 377 ? 146.288 139.840 152.328 1.00 75.49  ? 377 ALA A CB  1 
ATOM   2953 N  N   . LEU A 1 378 ? 143.529 140.890 151.220 1.00 71.75  ? 378 LEU A N   1 
ATOM   2954 C  CA  . LEU A 1 378 ? 142.538 141.061 150.136 1.00 68.85  ? 378 LEU A CA  1 
ATOM   2955 C  C   . LEU A 1 378 ? 142.141 142.538 149.972 1.00 74.45  ? 378 LEU A C   1 
ATOM   2956 O  O   . LEU A 1 378 ? 142.010 142.962 148.841 1.00 81.29  ? 378 LEU A O   1 
ATOM   2957 C  CB  . LEU A 1 378 ? 141.325 140.166 150.419 1.00 68.79  ? 378 LEU A CB  1 
ATOM   2958 C  CG  . LEU A 1 378 ? 141.431 138.675 150.128 1.00 79.09  ? 378 LEU A CG  1 
ATOM   2959 C  CD1 . LEU A 1 378 ? 140.329 137.924 150.855 1.00 74.70  ? 378 LEU A CD1 1 
ATOM   2960 C  CD2 . LEU A 1 378 ? 141.362 138.404 148.637 1.00 80.04  ? 378 LEU A CD2 1 
ATOM   2961 N  N   . PHE A 1 379 ? 142.007 143.280 151.061 1.00 80.89  ? 379 PHE A N   1 
ATOM   2962 C  CA  . PHE A 1 379 ? 141.718 144.708 150.965 1.00 81.00  ? 379 PHE A CA  1 
ATOM   2963 C  C   . PHE A 1 379 ? 142.871 145.454 150.308 1.00 82.80  ? 379 PHE A C   1 
ATOM   2964 O  O   . PHE A 1 379 ? 142.663 146.298 149.422 1.00 83.14  ? 379 PHE A O   1 
ATOM   2965 C  CB  . PHE A 1 379 ? 141.438 145.269 152.359 1.00 84.07  ? 379 PHE A CB  1 
ATOM   2966 C  CG  . PHE A 1 379 ? 140.250 146.180 152.421 1.00 91.30  ? 379 PHE A CG  1 
ATOM   2967 C  CD1 . PHE A 1 379 ? 139.021 145.705 152.849 1.00 91.01  ? 379 PHE A CD1 1 
ATOM   2968 C  CD2 . PHE A 1 379 ? 140.358 147.510 152.061 1.00 94.60  ? 379 PHE A CD2 1 
ATOM   2969 C  CE1 . PHE A 1 379 ? 137.923 146.538 152.911 1.00 99.12  ? 379 PHE A CE1 1 
ATOM   2970 C  CE2 . PHE A 1 379 ? 139.264 148.350 152.120 1.00 97.39  ? 379 PHE A CE2 1 
ATOM   2971 C  CZ  . PHE A 1 379 ? 138.044 147.861 152.546 1.00 102.26 ? 379 PHE A CZ  1 
ATOM   2972 N  N   . ILE A 1 380 ? 144.103 145.145 150.722 1.00 84.68  ? 380 ILE A N   1 
ATOM   2973 C  CA  . ILE A 1 380 ? 145.277 145.806 150.158 1.00 78.67  ? 380 ILE A CA  1 
ATOM   2974 C  C   . ILE A 1 380 ? 145.393 145.495 148.672 1.00 75.95  ? 380 ILE A C   1 
ATOM   2975 O  O   . ILE A 1 380 ? 145.668 146.380 147.857 1.00 85.19  ? 380 ILE A O   1 
ATOM   2976 C  CB  . ILE A 1 380 ? 146.548 145.393 150.922 1.00 81.05  ? 380 ILE A CB  1 
ATOM   2977 C  CG1 . ILE A 1 380 ? 146.667 146.189 152.222 1.00 84.50  ? 380 ILE A CG1 1 
ATOM   2978 C  CG2 . ILE A 1 380 ? 147.786 145.595 150.068 1.00 76.65  ? 380 ILE A CG2 1 
ATOM   2979 C  CD1 . ILE A 1 380 ? 147.746 145.679 153.146 1.00 85.32  ? 380 ILE A CD1 1 
ATOM   2980 N  N   . VAL A 1 381 ? 145.171 144.232 148.297 1.00 78.03  ? 381 VAL A N   1 
ATOM   2981 C  CA  . VAL A 1 381 ? 145.250 143.851 146.891 1.00 77.45  ? 381 VAL A CA  1 
ATOM   2982 C  C   . VAL A 1 381 ? 144.260 144.651 146.061 1.00 81.52  ? 381 VAL A C   1 
ATOM   2983 O  O   . VAL A 1 381 ? 144.636 145.258 145.050 1.00 90.10  ? 381 VAL A O   1 
ATOM   2984 C  CB  . VAL A 1 381 ? 145.017 142.338 146.726 1.00 77.03  ? 381 VAL A CB  1 
ATOM   2985 C  CG1 . VAL A 1 381 ? 144.633 142.012 145.293 1.00 71.94  ? 381 VAL A CG1 1 
ATOM   2986 C  CG2 . VAL A 1 381 ? 146.251 141.563 147.128 1.00 80.04  ? 381 VAL A CG2 1 
ATOM   2987 N  N   . VAL A 1 382 ? 142.995 144.693 146.481 1.00 78.59  ? 382 VAL A N   1 
ATOM   2988 C  CA  . VAL A 1 382 ? 141.980 145.379 145.684 1.00 78.95  ? 382 VAL A CA  1 
ATOM   2989 C  C   . VAL A 1 382 ? 142.298 146.867 145.575 1.00 82.95  ? 382 VAL A C   1 
ATOM   2990 O  O   . VAL A 1 382 ? 142.315 147.438 144.474 1.00 80.82  ? 382 VAL A O   1 
ATOM   2991 C  CB  . VAL A 1 382 ? 140.580 145.141 146.279 1.00 80.17  ? 382 VAL A CB  1 
ATOM   2992 C  CG1 . VAL A 1 382 ? 139.570 146.087 145.651 1.00 78.15  ? 382 VAL A CG1 1 
ATOM   2993 C  CG2 . VAL A 1 382 ? 140.159 143.696 146.083 1.00 78.77  ? 382 VAL A CG2 1 
ATOM   2994 N  N   . GLY A 1 383 ? 142.574 147.514 146.712 1.00 86.44  ? 383 GLY A N   1 
ATOM   2995 C  CA  . GLY A 1 383 ? 142.825 148.946 146.688 1.00 77.91  ? 383 GLY A CA  1 
ATOM   2996 C  C   . GLY A 1 383 ? 144.057 149.317 145.886 1.00 80.86  ? 383 GLY A C   1 
ATOM   2997 O  O   . GLY A 1 383 ? 144.025 150.247 145.072 1.00 90.43  ? 383 GLY A O   1 
ATOM   2998 N  N   . GLY A 1 384 ? 145.160 148.595 146.100 1.00 86.82  ? 384 GLY A N   1 
ATOM   2999 C  CA  . GLY A 1 384 ? 146.379 148.891 145.374 1.00 87.50  ? 384 GLY A CA  1 
ATOM   3000 C  C   . GLY A 1 384 ? 146.253 148.641 143.887 1.00 91.26  ? 384 GLY A C   1 
ATOM   3001 O  O   . GLY A 1 384 ? 146.761 149.417 143.076 1.00 98.99  ? 384 GLY A O   1 
ATOM   3002 N  N   . SER A 1 385 ? 145.627 147.553 143.503 1.00 85.43  ? 385 SER A N   1 
ATOM   3003 C  CA  . SER A 1 385 ? 145.430 147.315 142.061 1.00 81.47  ? 385 SER A CA  1 
ATOM   3004 C  C   . SER A 1 385 ? 144.575 148.426 141.428 1.00 88.70  ? 385 SER A C   1 
ATOM   3005 O  O   . SER A 1 385 ? 144.961 148.880 140.370 1.00 92.66  ? 385 SER A O   1 
ATOM   3006 C  CB  . SER A 1 385 ? 144.981 145.887 141.738 1.00 79.27  ? 385 SER A CB  1 
ATOM   3007 O  OG  . SER A 1 385 ? 143.651 145.594 142.108 1.00 94.19  ? 385 SER A OG  1 
ATOM   3008 N  N   . TYR A 1 386 ? 143.484 148.831 142.087 1.00 84.35  ? 386 TYR A N   1 
ATOM   3009 C  CA  . TYR A 1 386 ? 142.667 149.889 141.499 1.00 79.74  ? 386 TYR A CA  1 
ATOM   3010 C  C   . TYR A 1 386 ? 143.443 151.198 141.385 1.00 82.45  ? 386 TYR A C   1 
ATOM   3011 O  O   . TYR A 1 386 ? 143.364 151.888 140.359 1.00 85.14  ? 386 TYR A O   1 
ATOM   3012 C  CB  . TYR A 1 386 ? 141.390 150.085 142.311 1.00 87.16  ? 386 TYR A CB  1 
ATOM   3013 C  CG  . TYR A 1 386 ? 140.341 149.026 142.062 1.00 87.04  ? 386 TYR A CG  1 
ATOM   3014 C  CD1 . TYR A 1 386 ? 140.655 147.854 141.392 1.00 84.05  ? 386 TYR A CD1 1 
ATOM   3015 C  CD2 . TYR A 1 386 ? 139.035 149.204 142.490 1.00 87.90  ? 386 TYR A CD2 1 
ATOM   3016 C  CE1 . TYR A 1 386 ? 139.704 146.887 141.164 1.00 83.87  ? 386 TYR A CE1 1 
ATOM   3017 C  CE2 . TYR A 1 386 ? 138.074 148.242 142.262 1.00 90.83  ? 386 TYR A CE2 1 
ATOM   3018 C  CZ  . TYR A 1 386 ? 138.417 147.086 141.600 1.00 91.14  ? 386 TYR A CZ  1 
ATOM   3019 O  OH  . TYR A 1 386 ? 137.466 146.122 141.371 1.00 95.72  ? 386 TYR A OH  1 
ATOM   3020 N  N   . ALA A 1 387 ? 144.199 151.558 142.427 1.00 75.99  ? 387 ALA A N   1 
ATOM   3021 C  CA  . ALA A 1 387 ? 144.996 152.778 142.366 1.00 74.50  ? 387 ALA A CA  1 
ATOM   3022 C  C   . ALA A 1 387 ? 146.050 152.694 141.269 1.00 82.51  ? 387 ALA A C   1 
ATOM   3023 O  O   . ALA A 1 387 ? 146.296 153.675 140.553 1.00 91.12  ? 387 ALA A O   1 
ATOM   3024 C  CB  . ALA A 1 387 ? 145.646 153.048 143.721 1.00 75.54  ? 387 ALA A CB  1 
ATOM   3025 N  N   . GLY A 1 388 ? 146.683 151.529 141.125 1.00 76.30  ? 388 GLY A N   1 
ATOM   3026 C  CA  . GLY A 1 388 ? 147.656 151.352 140.064 1.00 75.92  ? 388 GLY A CA  1 
ATOM   3027 C  C   . GLY A 1 388 ? 147.041 151.469 138.685 1.00 79.25  ? 388 GLY A C   1 
ATOM   3028 O  O   . GLY A 1 388 ? 147.632 152.067 137.786 1.00 86.69  ? 388 GLY A O   1 
ATOM   3029 N  N   . ASN A 1 389 ? 145.894 150.893 138.432 1.00 77.70  ? 389 ASN A N   1 
ATOM   3030 C  CA  . ASN A 1 389 ? 145.117 151.035 137.177 1.00 78.99  ? 389 ASN A CA  1 
ATOM   3031 C  C   . ASN A 1 389 ? 144.784 152.511 136.898 1.00 79.32  ? 389 ASN A C   1 
ATOM   3032 O  O   . ASN A 1 389 ? 144.948 152.940 135.768 1.00 86.34  ? 389 ASN A O   1 
ATOM   3033 C  CB  . ASN A 1 389 ? 143.834 150.176 137.174 1.00 79.25  ? 389 ASN A CB  1 
ATOM   3034 C  CG  . ASN A 1 389 ? 143.980 148.675 137.226 1.00 87.23  ? 389 ASN A CG  1 
ATOM   3035 O  OD1 . ASN A 1 389 ? 144.769 148.067 136.509 1.00 93.62  ? 389 ASN A OD1 1 
ATOM   3036 N  ND2 . ASN A 1 389 ? 143.153 148.065 138.051 1.00 84.52  ? 389 ASN A ND2 1 
ATOM   3037 N  N   . PHE A 1 390 ? 144.384 153.250 137.923 1.00 80.90  ? 390 PHE A N   1 
ATOM   3038 C  CA  . PHE A 1 390 ? 144.090 154.667 137.725 1.00 79.74  ? 390 PHE A CA  1 
ATOM   3039 C  C   . PHE A 1 390 ? 145.344 155.435 137.319 1.00 80.64  ? 390 PHE A C   1 
ATOM   3040 O  O   . PHE A 1 390 ? 145.339 156.191 136.337 1.00 86.75  ? 390 PHE A O   1 
ATOM   3041 C  CB  . PHE A 1 390 ? 143.487 155.249 139.004 1.00 82.13  ? 390 PHE A CB  1 
ATOM   3042 C  CG  . PHE A 1 390 ? 143.334 156.743 138.981 1.00 81.85  ? 390 PHE A CG  1 
ATOM   3043 C  CD1 . PHE A 1 390 ? 142.231 157.330 138.387 1.00 89.35  ? 390 PHE A CD1 1 
ATOM   3044 C  CD2 . PHE A 1 390 ? 144.288 157.561 139.562 1.00 81.46  ? 390 PHE A CD2 1 
ATOM   3045 C  CE1 . PHE A 1 390 ? 142.086 158.701 138.367 1.00 87.43  ? 390 PHE A CE1 1 
ATOM   3046 C  CE2 . PHE A 1 390 ? 144.149 158.933 139.542 1.00 85.30  ? 390 PHE A CE2 1 
ATOM   3047 C  CZ  . PHE A 1 390 ? 143.046 159.503 138.944 1.00 81.32  ? 390 PHE A CZ  1 
ATOM   3048 N  N   . PHE A 1 391 ? 146.436 155.237 138.056 1.00 75.18  ? 391 PHE A N   1 
ATOM   3049 C  CA  . PHE A 1 391 ? 147.654 155.992 137.784 1.00 72.54  ? 391 PHE A CA  1 
ATOM   3050 C  C   . PHE A 1 391 ? 148.312 155.561 136.480 1.00 72.77  ? 391 PHE A C   1 
ATOM   3051 O  O   . PHE A 1 391 ? 148.990 156.367 135.836 1.00 74.12  ? 391 PHE A O   1 
ATOM   3052 C  CB  . PHE A 1 391 ? 148.625 155.851 138.954 1.00 73.99  ? 391 PHE A CB  1 
ATOM   3053 C  CG  . PHE A 1 391 ? 148.287 156.731 140.118 1.00 73.63  ? 391 PHE A CG  1 
ATOM   3054 C  CD1 . PHE A 1 391 ? 148.213 158.103 139.966 1.00 72.36  ? 391 PHE A CD1 1 
ATOM   3055 C  CD2 . PHE A 1 391 ? 148.015 156.186 141.360 1.00 76.19  ? 391 PHE A CD2 1 
ATOM   3056 C  CE1 . PHE A 1 391 ? 147.896 158.916 141.032 1.00 77.67  ? 391 PHE A CE1 1 
ATOM   3057 C  CE2 . PHE A 1 391 ? 147.693 156.995 142.430 1.00 77.78  ? 391 PHE A CE2 1 
ATOM   3058 C  CZ  . PHE A 1 391 ? 147.634 158.361 142.265 1.00 79.27  ? 391 PHE A CZ  1 
ATOM   3059 N  N   . ALA A 1 392 ? 148.123 154.305 136.071 1.00 69.75  ? 392 ALA A N   1 
ATOM   3060 C  CA  . ALA A 1 392 ? 148.663 153.861 134.794 1.00 67.33  ? 392 ALA A CA  1 
ATOM   3061 C  C   . ALA A 1 392 ? 147.887 154.458 133.630 1.00 70.43  ? 392 ALA A C   1 
ATOM   3062 O  O   . ALA A 1 392 ? 148.485 154.914 132.649 1.00 72.36  ? 392 ALA A O   1 
ATOM   3063 C  CB  . ALA A 1 392 ? 148.650 152.336 134.718 1.00 70.83  ? 392 ALA A CB  1 
ATOM   3064 N  N   . LEU A 1 393 ? 146.555 154.468 133.715 1.00 84.20  ? 393 LEU A N   1 
ATOM   3065 C  CA  . LEU A 1 393 ? 145.769 155.015 132.619 1.00 81.60  ? 393 LEU A CA  1 
ATOM   3066 C  C   . LEU A 1 393 ? 145.834 156.533 132.544 1.00 84.84  ? 393 LEU A C   1 
ATOM   3067 O  O   . LEU A 1 393 ? 145.646 157.090 131.457 1.00 82.39  ? 393 LEU A O   1 
ATOM   3068 C  CB  . LEU A 1 393 ? 144.313 154.557 132.722 1.00 86.38  ? 393 LEU A CB  1 
ATOM   3069 C  CG  . LEU A 1 393 ? 144.112 153.068 132.437 1.00 79.26  ? 393 LEU A CG  1 
ATOM   3070 C  CD1 . LEU A 1 393 ? 142.646 152.753 132.243 1.00 83.39  ? 393 LEU A CD1 1 
ATOM   3071 C  CD2 . LEU A 1 393 ? 144.919 152.634 131.226 1.00 72.28  ? 393 LEU A CD2 1 
ATOM   3072 N  N   . THR A 1 394 ? 146.099 157.218 133.656 1.00 82.76  ? 394 THR A N   1 
ATOM   3073 C  CA  . THR A 1 394 ? 146.358 158.650 133.580 1.00 75.19  ? 394 THR A CA  1 
ATOM   3074 C  C   . THR A 1 394 ? 147.789 158.965 133.163 1.00 78.04  ? 394 THR A C   1 
ATOM   3075 O  O   . THR A 1 394 ? 148.112 160.139 132.953 1.00 83.36  ? 394 THR A O   1 
ATOM   3076 C  CB  . THR A 1 394 ? 146.063 159.323 134.921 1.00 80.07  ? 394 THR A CB  1 
ATOM   3077 O  OG1 . THR A 1 394 ? 146.613 158.536 135.984 1.00 91.69  ? 394 THR A OG1 1 
ATOM   3078 C  CG2 . THR A 1 394 ? 144.568 159.472 135.125 1.00 82.63  ? 394 THR A CG2 1 
ATOM   3079 N  N   . HIS A 1 395 ? 148.640 157.942 133.052 1.00 82.23  ? 395 HIS A N   1 
ATOM   3080 C  CA  . HIS A 1 395 ? 150.025 158.061 132.605 1.00 85.45  ? 395 HIS A CA  1 
ATOM   3081 C  C   . HIS A 1 395 ? 150.881 158.866 133.575 1.00 85.90  ? 395 HIS A C   1 
ATOM   3082 O  O   . HIS A 1 395 ? 151.968 159.328 133.210 1.00 83.67  ? 395 HIS A O   1 
ATOM   3083 C  CB  . HIS A 1 395 ? 150.090 158.666 131.201 1.00 79.25  ? 395 HIS A CB  1 
ATOM   3084 C  CG  . HIS A 1 395 ? 149.704 157.710 130.118 1.00 81.75  ? 395 HIS A CG  1 
ATOM   3085 N  ND1 . HIS A 1 395 ? 150.483 156.629 129.765 1.00 83.24  ? 395 HIS A ND1 1 
ATOM   3086 C  CD2 . HIS A 1 395 ? 148.612 157.661 129.318 1.00 83.61  ? 395 HIS A CD2 1 
ATOM   3087 C  CE1 . HIS A 1 395 ? 149.892 155.959 128.792 1.00 86.10  ? 395 HIS A CE1 1 
ATOM   3088 N  NE2 . HIS A 1 395 ? 148.754 156.566 128.502 1.00 86.78  ? 395 HIS A NE2 1 
ATOM   3089 N  N   . ILE A 1 396 ? 150.409 159.044 134.809 1.00 82.63  ? 396 ILE A N   1 
ATOM   3090 C  CA  . ILE A 1 396 ? 151.284 159.574 135.848 1.00 82.69  ? 396 ILE A CA  1 
ATOM   3091 C  C   . ILE A 1 396 ? 152.341 158.545 136.226 1.00 85.62  ? 396 ILE A C   1 
ATOM   3092 O  O   . ILE A 1 396 ? 153.505 158.898 136.448 1.00 87.26  ? 396 ILE A O   1 
ATOM   3093 C  CB  . ILE A 1 396 ? 150.467 160.023 137.073 1.00 80.26  ? 396 ILE A CB  1 
ATOM   3094 C  CG1 . ILE A 1 396 ? 149.690 161.301 136.761 1.00 80.59  ? 396 ILE A CG1 1 
ATOM   3095 C  CG2 . ILE A 1 396 ? 151.365 160.235 138.282 1.00 83.88  ? 396 ILE A CG2 1 
ATOM   3096 C  CD1 . ILE A 1 396 ? 148.217 161.206 137.035 1.00 87.84  ? 396 ILE A CD1 1 
ATOM   3097 N  N   . LEU A 1 397 ? 151.974 157.285 136.311 1.00 85.28  ? 397 LEU A N   1 
ATOM   3098 C  CA  . LEU A 1 397 ? 152.921 156.176 136.543 1.00 85.86  ? 397 LEU A CA  1 
ATOM   3099 C  C   . LEU A 1 397 ? 153.971 156.160 135.448 1.00 83.85  ? 397 LEU A C   1 
ATOM   3100 O  O   . LEU A 1 397 ? 153.631 156.182 134.263 1.00 84.90  ? 397 LEU A O   1 
ATOM   3101 C  CB  . LEU A 1 397 ? 152.151 154.852 136.599 1.00 79.15  ? 397 LEU A CB  1 
ATOM   3102 C  CG  . LEU A 1 397 ? 152.930 153.636 137.099 1.00 80.44  ? 397 LEU A CG  1 
ATOM   3103 C  CD1 . LEU A 1 397 ? 153.346 153.806 138.548 1.00 82.00  ? 397 LEU A CD1 1 
ATOM   3104 C  CD2 . LEU A 1 397 ? 152.135 152.352 136.911 1.00 79.18  ? 397 LEU A CD2 1 
ATOM   3105 N  N   . PRO A 1 398 ? 155.251 156.180 135.809 1.00 92.36  ? 398 PRO A N   1 
ATOM   3106 C  CA  . PRO A 1 398 ? 156.291 156.061 134.782 1.00 88.47  ? 398 PRO A CA  1 
ATOM   3107 C  C   . PRO A 1 398 ? 156.226 154.712 134.090 1.00 96.71  ? 398 PRO A C   1 
ATOM   3108 O  O   . PRO A 1 398 ? 155.865 153.701 134.712 1.00 101.51 ? 398 PRO A O   1 
ATOM   3109 C  CB  . PRO A 1 398 ? 157.597 156.230 135.577 1.00 88.48  ? 398 PRO A CB  1 
ATOM   3110 C  CG  . PRO A 1 398 ? 157.221 156.048 137.006 1.00 91.18  ? 398 PRO A CG  1 
ATOM   3111 C  CD  . PRO A 1 398 ? 155.809 156.490 137.133 1.00 95.04  ? 398 PRO A CD  1 
ATOM   3112 N  N   . PRO A 1 399 ? 156.561 154.655 132.797 1.00 94.84  ? 399 PRO A N   1 
ATOM   3113 C  CA  . PRO A 1 399 ? 156.297 153.431 132.019 1.00 90.53  ? 399 PRO A CA  1 
ATOM   3114 C  C   . PRO A 1 399 ? 157.096 152.212 132.459 1.00 93.82  ? 399 PRO A C   1 
ATOM   3115 O  O   . PRO A 1 399 ? 156.676 151.087 132.163 1.00 92.60  ? 399 PRO A O   1 
ATOM   3116 C  CB  . PRO A 1 399 ? 156.654 153.842 130.584 1.00 85.58  ? 399 PRO A CB  1 
ATOM   3117 C  CG  . PRO A 1 399 ? 156.685 155.336 130.592 1.00 89.24  ? 399 PRO A CG  1 
ATOM   3118 C  CD  . PRO A 1 399 ? 157.118 155.731 131.961 1.00 92.77  ? 399 PRO A CD  1 
ATOM   3119 N  N   . GLU A 1 400 ? 158.300 152.297 132.977 1.00 108.03 ? 400 GLU A N   1 
ATOM   3120 C  CA  . GLU A 1 400 ? 159.061 151.120 133.477 1.00 104.11 ? 400 GLU A CA  1 
ATOM   3121 C  C   . GLU A 1 400 ? 158.413 150.416 134.684 1.00 103.82 ? 400 GLU A C   1 
ATOM   3122 O  O   . GLU A 1 400 ? 158.830 149.315 134.955 1.00 106.48 ? 400 GLU A O   1 
ATOM   3123 C  CB  . GLU A 1 400 ? 160.503 151.536 133.775 1.00 102.52 ? 400 GLU A CB  1 
ATOM   3124 C  CG  . GLU A 1 400 ? 160.625 152.717 134.713 1.00 107.48 ? 400 GLU A CG  1 
ATOM   3125 C  CD  . GLU A 1 400 ? 160.345 154.071 134.084 1.00 113.30 ? 400 GLU A CD  1 
ATOM   3126 O  OE1 . GLU A 1 400 ? 160.005 154.115 132.892 1.00 117.00 ? 400 GLU A OE1 1 
ATOM   3127 O  OE2 . GLU A 1 400 ? 160.474 155.080 134.787 1.00 112.70 ? 400 GLU A OE2 1 
ATOM   3128 N  N   . PHE A 1 401 ? 157.464 151.009 135.397 1.00 89.09  ? 401 PHE A N   1 
ATOM   3129 C  CA  . PHE A 1 401 ? 156.751 150.310 136.458 1.00 89.08  ? 401 PHE A CA  1 
ATOM   3130 C  C   . PHE A 1 401 ? 155.324 149.945 136.078 1.00 90.36  ? 401 PHE A C   1 
ATOM   3131 O  O   . PHE A 1 401 ? 154.552 149.536 136.950 1.00 99.42  ? 401 PHE A O   1 
ATOM   3132 C  CB  . PHE A 1 401 ? 156.737 151.158 137.733 1.00 89.49  ? 401 PHE A CB  1 
ATOM   3133 C  CG  . PHE A 1 401 ? 158.092 151.636 138.158 1.00 94.86  ? 401 PHE A CG  1 
ATOM   3134 C  CD1 . PHE A 1 401 ? 159.009 150.757 138.707 1.00 98.30  ? 401 PHE A CD1 1 
ATOM   3135 C  CD2 . PHE A 1 401 ? 158.451 152.961 138.009 1.00 92.31  ? 401 PHE A CD2 1 
ATOM   3136 C  CE1 . PHE A 1 401 ? 160.255 151.192 139.101 1.00 99.24  ? 401 PHE A CE1 1 
ATOM   3137 C  CE2 . PHE A 1 401 ? 159.698 153.404 138.400 1.00 97.32  ? 401 PHE A CE2 1 
ATOM   3138 C  CZ  . PHE A 1 401 ? 160.601 152.519 138.946 1.00 100.00 ? 401 PHE A CZ  1 
ATOM   3139 N  N   . ASN A 1 402 ? 154.952 150.093 134.805 1.00 78.56  ? 402 ASN A N   1 
ATOM   3140 C  CA  . ASN A 1 402 ? 153.559 149.892 134.417 1.00 81.09  ? 402 ASN A CA  1 
ATOM   3141 C  C   . ASN A 1 402 ? 153.140 148.437 134.582 1.00 81.34  ? 402 ASN A C   1 
ATOM   3142 O  O   . ASN A 1 402 ? 152.113 148.146 135.200 1.00 85.11  ? 402 ASN A O   1 
ATOM   3143 C  CB  . ASN A 1 402 ? 153.341 150.359 132.978 1.00 81.26  ? 402 ASN A CB  1 
ATOM   3144 C  CG  . ASN A 1 402 ? 151.996 149.940 132.430 1.00 84.09  ? 402 ASN A CG  1 
ATOM   3145 O  OD1 . ASN A 1 402 ? 150.972 150.538 132.751 1.00 90.21  ? 402 ASN A OD1 1 
ATOM   3146 N  ND2 . ASN A 1 402 ? 151.989 148.912 131.593 1.00 84.16  ? 402 ASN A ND2 1 
ATOM   3147 N  N   . PHE A 1 403 ? 153.938 147.504 134.057 1.00 72.43  ? 403 PHE A N   1 
ATOM   3148 C  CA  . PHE A 1 403 ? 153.553 146.098 134.111 1.00 72.36  ? 403 PHE A CA  1 
ATOM   3149 C  C   . PHE A 1 403 ? 153.497 145.562 135.537 1.00 80.85  ? 403 PHE A C   1 
ATOM   3150 O  O   . PHE A 1 403 ? 152.784 144.585 135.789 1.00 85.96  ? 403 PHE A O   1 
ATOM   3151 C  CB  . PHE A 1 403 ? 154.516 145.251 133.279 1.00 71.83  ? 403 PHE A CB  1 
ATOM   3152 C  CG  . PHE A 1 403 ? 154.087 143.821 133.132 1.00 74.20  ? 403 PHE A CG  1 
ATOM   3153 C  CD1 . PHE A 1 403 ? 153.111 143.470 132.215 1.00 75.30  ? 403 PHE A CD1 1 
ATOM   3154 C  CD2 . PHE A 1 403 ? 154.651 142.828 133.912 1.00 80.37  ? 403 PHE A CD2 1 
ATOM   3155 C  CE1 . PHE A 1 403 ? 152.709 142.156 132.079 1.00 78.73  ? 403 PHE A CE1 1 
ATOM   3156 C  CE2 . PHE A 1 403 ? 154.253 141.513 133.780 1.00 82.82  ? 403 PHE A CE2 1 
ATOM   3157 C  CZ  . PHE A 1 403 ? 153.281 141.179 132.864 1.00 83.79  ? 403 PHE A CZ  1 
ATOM   3158 N  N   . TRP A 1 404 ? 154.211 146.180 136.473 1.00 86.57  ? 404 TRP A N   1 
ATOM   3159 C  CA  . TRP A 1 404 ? 154.267 145.673 137.837 1.00 84.17  ? 404 TRP A CA  1 
ATOM   3160 C  C   . TRP A 1 404 ? 153.326 146.385 138.800 1.00 86.86  ? 404 TRP A C   1 
ATOM   3161 O  O   . TRP A 1 404 ? 152.872 145.760 139.764 1.00 90.51  ? 404 TRP A O   1 
ATOM   3162 C  CB  . TRP A 1 404 ? 155.697 145.763 138.377 1.00 84.95  ? 404 TRP A CB  1 
ATOM   3163 C  CG  . TRP A 1 404 ? 156.537 144.573 138.024 1.00 81.75  ? 404 TRP A CG  1 
ATOM   3164 C  CD1 . TRP A 1 404 ? 157.177 144.345 136.845 1.00 85.53  ? 404 TRP A CD1 1 
ATOM   3165 C  CD2 . TRP A 1 404 ? 156.823 143.447 138.860 1.00 86.30  ? 404 TRP A CD2 1 
ATOM   3166 N  NE1 . TRP A 1 404 ? 157.846 143.148 136.891 1.00 87.27  ? 404 TRP A NE1 1 
ATOM   3167 C  CE2 . TRP A 1 404 ? 157.644 142.576 138.119 1.00 87.03  ? 404 TRP A CE2 1 
ATOM   3168 C  CE3 . TRP A 1 404 ? 156.465 143.090 140.163 1.00 90.29  ? 404 TRP A CE3 1 
ATOM   3169 C  CZ2 . TRP A 1 404 ? 158.112 141.374 138.636 1.00 87.59  ? 404 TRP A CZ2 1 
ATOM   3170 C  CZ3 . TRP A 1 404 ? 156.932 141.896 140.673 1.00 84.28  ? 404 TRP A CZ3 1 
ATOM   3171 C  CH2 . TRP A 1 404 ? 157.746 141.052 139.912 1.00 84.07  ? 404 TRP A CH2 1 
ATOM   3172 N  N   . PHE A 1 405 ? 153.007 147.664 138.576 1.00 81.49  ? 405 PHE A N   1 
ATOM   3173 C  CA  . PHE A 1 405 ? 152.181 148.386 139.538 1.00 77.24  ? 405 PHE A CA  1 
ATOM   3174 C  C   . PHE A 1 405 ? 151.049 149.152 138.866 1.00 80.70  ? 405 PHE A C   1 
ATOM   3175 O  O   . PHE A 1 405 ? 150.464 150.052 139.475 1.00 96.90  ? 405 PHE A O   1 
ATOM   3176 C  CB  . PHE A 1 405 ? 153.021 149.359 140.368 1.00 82.30  ? 405 PHE A CB  1 
ATOM   3177 C  CG  . PHE A 1 405 ? 154.136 148.707 141.126 1.00 76.72  ? 405 PHE A CG  1 
ATOM   3178 C  CD1 . PHE A 1 405 ? 153.918 148.169 142.382 1.00 81.74  ? 405 PHE A CD1 1 
ATOM   3179 C  CD2 . PHE A 1 405 ? 155.408 148.639 140.587 1.00 77.43  ? 405 PHE A CD2 1 
ATOM   3180 C  CE1 . PHE A 1 405 ? 154.942 147.572 143.081 1.00 84.20  ? 405 PHE A CE1 1 
ATOM   3181 C  CE2 . PHE A 1 405 ? 156.437 148.041 141.281 1.00 84.15  ? 405 PHE A CE2 1 
ATOM   3182 C  CZ  . PHE A 1 405 ? 156.204 147.507 142.529 1.00 87.39  ? 405 PHE A CZ  1 
ATOM   3183 N  N   . GLY A 1 406 ? 150.717 148.810 137.627 1.00 73.89  ? 406 GLY A N   1 
ATOM   3184 C  CA  . GLY A 1 406 ? 149.728 149.568 136.890 1.00 79.05  ? 406 GLY A CA  1 
ATOM   3185 C  C   . GLY A 1 406 ? 148.711 148.695 136.189 1.00 85.01  ? 406 GLY A C   1 
ATOM   3186 O  O   . GLY A 1 406 ? 148.005 147.915 136.831 1.00 91.45  ? 406 GLY A O   1 
ATOM   3187 N  N   . HIS A 1 407 ? 148.619 148.834 134.872 1.00 79.77  ? 407 HIS A N   1 
ATOM   3188 C  CA  . HIS A 1 407 ? 147.701 148.046 134.060 1.00 75.55  ? 407 HIS A CA  1 
ATOM   3189 C  C   . HIS A 1 407 ? 148.501 147.042 133.239 1.00 82.55  ? 407 HIS A C   1 
ATOM   3190 O  O   . HIS A 1 407 ? 149.419 147.423 132.506 1.00 86.51  ? 407 HIS A O   1 
ATOM   3191 C  CB  . HIS A 1 407 ? 146.873 148.952 133.151 1.00 76.06  ? 407 HIS A CB  1 
ATOM   3192 C  CG  . HIS A 1 407 ? 145.536 148.387 132.793 1.00 79.94  ? 407 HIS A CG  1 
ATOM   3193 N  ND1 . HIS A 1 407 ? 145.388 147.229 132.065 1.00 83.65  ? 407 HIS A ND1 1 
ATOM   3194 C  CD2 . HIS A 1 407 ? 144.284 148.822 133.065 1.00 86.70  ? 407 HIS A CD2 1 
ATOM   3195 C  CE1 . HIS A 1 407 ? 144.102 146.974 131.902 1.00 86.73  ? 407 HIS A CE1 1 
ATOM   3196 N  NE2 . HIS A 1 407 ? 143.411 147.926 132.500 1.00 90.83  ? 407 HIS A NE2 1 
ATOM   3197 N  N   . GLN A 1 408 ? 148.154 145.761 133.368 1.00 83.28  ? 408 GLN A N   1 
ATOM   3198 C  CA  . GLN A 1 408 ? 148.844 144.732 132.597 1.00 74.63  ? 408 GLN A CA  1 
ATOM   3199 C  C   . GLN A 1 408 ? 148.413 144.738 131.137 1.00 83.69  ? 408 GLN A C   1 
ATOM   3200 O  O   . GLN A 1 408 ? 149.176 144.309 130.266 1.00 90.50  ? 408 GLN A O   1 
ATOM   3201 C  CB  . GLN A 1 408 ? 148.601 143.358 133.217 1.00 70.65  ? 408 GLN A CB  1 
ATOM   3202 C  CG  . GLN A 1 408 ? 149.753 142.848 134.060 1.00 76.73  ? 408 GLN A CG  1 
ATOM   3203 C  CD  . GLN A 1 408 ? 149.620 141.381 134.406 1.00 84.54  ? 408 GLN A CD  1 
ATOM   3204 O  OE1 . GLN A 1 408 ? 149.567 140.527 133.524 1.00 87.41  ? 408 GLN A OE1 1 
ATOM   3205 N  NE2 . GLN A 1 408 ? 149.568 141.081 135.697 1.00 87.64  ? 408 GLN A NE2 1 
ATOM   3206 N  N   . GLY A 1 409 ? 147.201 145.208 130.851 1.00 79.32  ? 409 GLY A N   1 
ATOM   3207 C  CA  . GLY A 1 409 ? 146.685 145.265 129.503 1.00 77.31  ? 409 GLY A CA  1 
ATOM   3208 C  C   . GLY A 1 409 ? 146.014 143.996 129.028 1.00 79.32  ? 409 GLY A C   1 
ATOM   3209 O  O   . GLY A 1 409 ? 145.455 143.986 127.927 1.00 86.75  ? 409 GLY A O   1 
ATOM   3210 N  N   . TYR A 1 410 ? 146.050 142.932 129.822 1.00 71.12  ? 410 TYR A N   1 
ATOM   3211 C  CA  . TYR A 1 410 ? 145.432 141.667 129.463 1.00 65.94  ? 410 TYR A CA  1 
ATOM   3212 C  C   . TYR A 1 410 ? 144.155 141.474 130.266 1.00 73.00  ? 410 TYR A C   1 
ATOM   3213 O  O   . TYR A 1 410 ? 144.151 141.622 131.490 1.00 82.12  ? 410 TYR A O   1 
ATOM   3214 C  CB  . TYR A 1 410 ? 146.396 140.504 129.705 1.00 55.97  ? 410 TYR A CB  1 
ATOM   3215 C  CG  . TYR A 1 410 ? 147.756 140.713 129.080 1.00 66.09  ? 410 TYR A CG  1 
ATOM   3216 C  CD1 . TYR A 1 410 ? 147.878 141.214 127.791 1.00 76.91  ? 410 TYR A CD1 1 
ATOM   3217 C  CD2 . TYR A 1 410 ? 148.917 140.415 129.777 1.00 70.28  ? 410 TYR A CD2 1 
ATOM   3218 C  CE1 . TYR A 1 410 ? 149.115 141.407 127.215 1.00 77.60  ? 410 TYR A CE1 1 
ATOM   3219 C  CE2 . TYR A 1 410 ? 150.160 140.606 129.210 1.00 71.72  ? 410 TYR A CE2 1 
ATOM   3220 C  CZ  . TYR A 1 410 ? 150.251 141.101 127.928 1.00 76.90  ? 410 TYR A CZ  1 
ATOM   3221 O  OH  . TYR A 1 410 ? 151.485 141.292 127.354 1.00 77.39  ? 410 TYR A OH  1 
ATOM   3222 N  N   . GLU A 1 411 ? 143.076 141.144 129.564 1.00 68.47  ? 411 GLU A N   1 
ATOM   3223 C  CA  . GLU A 1 411 ? 141.762 141.072 130.186 1.00 69.74  ? 411 GLU A CA  1 
ATOM   3224 C  C   . GLU A 1 411 ? 141.722 139.992 131.259 1.00 64.71  ? 411 GLU A C   1 
ATOM   3225 O  O   . GLU A 1 411 ? 142.354 138.940 131.123 1.00 61.71  ? 411 GLU A O   1 
ATOM   3226 C  CB  . GLU A 1 411 ? 140.698 140.806 129.122 1.00 62.67  ? 411 GLU A CB  1 
ATOM   3227 C  CG  . GLU A 1 411 ? 139.294 141.202 129.521 1.00 67.91  ? 411 GLU A CG  1 
ATOM   3228 C  CD  . GLU A 1 411 ? 138.305 141.013 128.393 1.00 83.61  ? 411 GLU A CD  1 
ATOM   3229 O  OE1 . GLU A 1 411 ? 138.655 140.339 127.405 1.00 82.50  ? 411 GLU A OE1 1 
ATOM   3230 O  OE2 . GLU A 1 411 ? 137.178 141.538 128.493 1.00 79.15  ? 411 GLU A OE2 1 
ATOM   3231 N  N   . TYR A 1 412 ? 141.003 140.285 132.347 1.00 74.99  ? 412 TYR A N   1 
ATOM   3232 C  CA  . TYR A 1 412 ? 140.804 139.392 133.488 1.00 70.44  ? 412 TYR A CA  1 
ATOM   3233 C  C   . TYR A 1 412 ? 142.072 139.254 134.321 1.00 72.94  ? 412 TYR A C   1 
ATOM   3234 O  O   . TYR A 1 412 ? 142.056 138.635 135.388 1.00 80.53  ? 412 TYR A O   1 
ATOM   3235 C  CB  . TYR A 1 412 ? 140.311 138.014 133.031 1.00 69.44  ? 412 TYR A CB  1 
ATOM   3236 C  CG  . TYR A 1 412 ? 139.028 138.064 132.239 1.00 74.31  ? 412 TYR A CG  1 
ATOM   3237 C  CD1 . TYR A 1 412 ? 137.823 138.366 132.852 1.00 72.38  ? 412 TYR A CD1 1 
ATOM   3238 C  CD2 . TYR A 1 412 ? 139.025 137.825 130.873 1.00 69.79  ? 412 TYR A CD2 1 
ATOM   3239 C  CE1 . TYR A 1 412 ? 136.650 138.420 132.132 1.00 69.80  ? 412 TYR A CE1 1 
ATOM   3240 C  CE2 . TYR A 1 412 ? 137.858 137.872 130.144 1.00 67.66  ? 412 TYR A CE2 1 
ATOM   3241 C  CZ  . TYR A 1 412 ? 136.673 138.172 130.777 1.00 68.38  ? 412 TYR A CZ  1 
ATOM   3242 O  OH  . TYR A 1 412 ? 135.507 138.224 130.053 1.00 85.02  ? 412 TYR A OH  1 
ATOM   3243 N  N   . LEU A 1 413 ? 143.170 139.835 133.847 1.00 81.45  ? 413 LEU A N   1 
ATOM   3244 C  CA  . LEU A 1 413 ? 144.436 139.861 134.570 1.00 77.29  ? 413 LEU A CA  1 
ATOM   3245 C  C   . LEU A 1 413 ? 145.038 141.254 134.499 1.00 80.92  ? 413 LEU A C   1 
ATOM   3246 O  O   . LEU A 1 413 ? 146.256 141.422 134.397 1.00 87.72  ? 413 LEU A O   1 
ATOM   3247 C  CB  . LEU A 1 413 ? 145.411 138.819 134.024 1.00 72.73  ? 413 LEU A CB  1 
ATOM   3248 C  CG  . LEU A 1 413 ? 145.079 137.350 134.302 1.00 72.86  ? 413 LEU A CG  1 
ATOM   3249 C  CD1 . LEU A 1 413 ? 146.102 136.437 133.650 1.00 68.69  ? 413 LEU A CD1 1 
ATOM   3250 C  CD2 . LEU A 1 413 ? 145.001 137.088 135.794 1.00 76.73  ? 413 LEU A CD2 1 
ATOM   3251 N  N   . ASP A 1 414 ? 144.181 142.275 134.552 1.00 78.34  ? 414 ASP A N   1 
ATOM   3252 C  CA  . ASP A 1 414 ? 144.618 143.652 134.363 1.00 74.91  ? 414 ASP A CA  1 
ATOM   3253 C  C   . ASP A 1 414 ? 145.453 144.171 135.522 1.00 81.41  ? 414 ASP A C   1 
ATOM   3254 O  O   . ASP A 1 414 ? 146.205 145.133 135.342 1.00 82.42  ? 414 ASP A O   1 
ATOM   3255 C  CB  . ASP A 1 414 ? 143.402 144.553 134.162 1.00 79.49  ? 414 ASP A CB  1 
ATOM   3256 C  CG  . ASP A 1 414 ? 142.405 143.972 133.186 1.00 84.58  ? 414 ASP A CG  1 
ATOM   3257 O  OD1 . ASP A 1 414 ? 142.602 144.136 131.965 1.00 91.07  ? 414 ASP A OD1 1 
ATOM   3258 O  OD2 . ASP A 1 414 ? 141.423 143.348 133.637 1.00 78.81  ? 414 ASP A OD2 1 
ATOM   3259 N  N   . LEU A 1 415 ? 145.336 143.566 136.697 1.00 78.84  ? 415 LEU A N   1 
ATOM   3260 C  CA  . LEU A 1 415 ? 146.104 144.009 137.851 1.00 73.24  ? 415 LEU A CA  1 
ATOM   3261 C  C   . LEU A 1 415 ? 147.594 143.781 137.620 1.00 77.95  ? 415 LEU A C   1 
ATOM   3262 O  O   . LEU A 1 415 ? 148.001 142.870 136.897 1.00 87.38  ? 415 LEU A O   1 
ATOM   3263 C  CB  . LEU A 1 415 ? 145.637 143.277 139.109 1.00 73.01  ? 415 LEU A CB  1 
ATOM   3264 C  CG  . LEU A 1 415 ? 146.042 141.814 139.312 1.00 74.12  ? 415 LEU A CG  1 
ATOM   3265 C  CD1 . LEU A 1 415 ? 145.912 141.434 140.774 1.00 78.53  ? 415 LEU A CD1 1 
ATOM   3266 C  CD2 . LEU A 1 415 ? 145.220 140.875 138.444 1.00 79.83  ? 415 LEU A CD2 1 
ATOM   3267 N  N   . GLY A 1 416 ? 148.407 144.632 138.240 1.00 82.77  ? 416 GLY A N   1 
ATOM   3268 C  CA  . GLY A 1 416 ? 149.840 144.536 138.069 1.00 79.24  ? 416 GLY A CA  1 
ATOM   3269 C  C   . GLY A 1 416 ? 150.402 143.239 138.619 1.00 80.51  ? 416 GLY A C   1 
ATOM   3270 O  O   . GLY A 1 416 ? 149.764 142.527 139.392 1.00 92.71  ? 416 GLY A O   1 
ATOM   3271 N  N   . ARG A 1 417 ? 151.628 142.928 138.191 1.00 63.11  ? 417 ARG A N   1 
ATOM   3272 C  CA  . ARG A 1 417 ? 152.262 141.676 138.589 1.00 75.92  ? 417 ARG A CA  1 
ATOM   3273 C  C   . ARG A 1 417 ? 152.500 141.628 140.095 1.00 83.17  ? 417 ARG A C   1 
ATOM   3274 O  O   . ARG A 1 417 ? 152.391 140.561 140.709 1.00 88.40  ? 417 ARG A O   1 
ATOM   3275 C  CB  . ARG A 1 417 ? 153.570 141.490 137.817 1.00 72.31  ? 417 ARG A CB  1 
ATOM   3276 C  CG  . ARG A 1 417 ? 154.358 140.228 138.154 1.00 71.49  ? 417 ARG A CG  1 
ATOM   3277 C  CD  . ARG A 1 417 ? 153.507 138.966 138.139 1.00 73.35  ? 417 ARG A CD  1 
ATOM   3278 N  NE  . ARG A 1 417 ? 152.818 138.750 136.873 1.00 72.54  ? 417 ARG A NE  1 
ATOM   3279 C  CZ  . ARG A 1 417 ? 153.329 138.086 135.846 1.00 78.36  ? 417 ARG A CZ  1 
ATOM   3280 N  NH1 . ARG A 1 417 ? 154.559 137.602 135.881 1.00 83.86  ? 417 ARG A NH1 1 
ATOM   3281 N  NH2 . ARG A 1 417 ? 152.589 137.904 134.757 1.00 74.98  ? 417 ARG A NH2 1 
ATOM   3282 N  N   . PHE A 1 418 ? 152.816 142.770 140.708 1.00 75.51  ? 418 PHE A N   1 
ATOM   3283 C  CA  . PHE A 1 418 ? 152.995 142.807 142.156 1.00 71.93  ? 418 PHE A CA  1 
ATOM   3284 C  C   . PHE A 1 418 ? 151.704 142.450 142.886 1.00 79.31  ? 418 PHE A C   1 
ATOM   3285 O  O   . PHE A 1 418 ? 151.709 141.655 143.834 1.00 89.54  ? 418 PHE A O   1 
ATOM   3286 C  CB  . PHE A 1 418 ? 153.488 144.189 142.580 1.00 73.60  ? 418 PHE A CB  1 
ATOM   3287 C  CG  . PHE A 1 418 ? 153.755 144.317 144.047 1.00 75.59  ? 418 PHE A CG  1 
ATOM   3288 C  CD1 . PHE A 1 418 ? 154.905 143.785 144.602 1.00 82.12  ? 418 PHE A CD1 1 
ATOM   3289 C  CD2 . PHE A 1 418 ? 152.859 144.970 144.873 1.00 77.50  ? 418 PHE A CD2 1 
ATOM   3290 C  CE1 . PHE A 1 418 ? 155.154 143.903 145.953 1.00 83.28  ? 418 PHE A CE1 1 
ATOM   3291 C  CE2 . PHE A 1 418 ? 153.102 145.091 146.223 1.00 81.44  ? 418 PHE A CE2 1 
ATOM   3292 C  CZ  . PHE A 1 418 ? 154.252 144.556 146.763 1.00 84.36  ? 418 PHE A CZ  1 
ATOM   3293 N  N   . TRP A 1 419 ? 150.581 143.020 142.444 1.00 70.80  ? 419 TRP A N   1 
ATOM   3294 C  CA  . TRP A 1 419 ? 149.297 142.708 143.064 1.00 69.14  ? 419 TRP A CA  1 
ATOM   3295 C  C   . TRP A 1 419 ? 148.890 141.267 142.787 1.00 76.41  ? 419 TRP A C   1 
ATOM   3296 O  O   . TRP A 1 419 ? 148.270 140.617 143.635 1.00 90.57  ? 419 TRP A O   1 
ATOM   3297 C  CB  . TRP A 1 419 ? 148.235 143.687 142.572 1.00 66.97  ? 419 TRP A CB  1 
ATOM   3298 C  CG  . TRP A 1 419 ? 148.713 145.105 142.569 1.00 74.65  ? 419 TRP A CG  1 
ATOM   3299 C  CD1 . TRP A 1 419 ? 148.930 145.894 141.480 1.00 86.89  ? 419 TRP A CD1 1 
ATOM   3300 C  CD2 . TRP A 1 419 ? 149.038 145.902 143.712 1.00 72.28  ? 419 TRP A CD2 1 
ATOM   3301 N  NE1 . TRP A 1 419 ? 149.372 147.132 141.873 1.00 88.95  ? 419 TRP A NE1 1 
ATOM   3302 C  CE2 . TRP A 1 419 ? 149.447 147.164 143.239 1.00 83.03  ? 419 TRP A CE2 1 
ATOM   3303 C  CE3 . TRP A 1 419 ? 149.026 145.673 145.092 1.00 74.78  ? 419 TRP A CE3 1 
ATOM   3304 C  CZ2 . TRP A 1 419 ? 149.837 148.191 144.093 1.00 80.43  ? 419 TRP A CZ2 1 
ATOM   3305 C  CZ3 . TRP A 1 419 ? 149.414 146.692 145.937 1.00 75.78  ? 419 TRP A CZ3 1 
ATOM   3306 C  CH2 . TRP A 1 419 ? 149.814 147.935 145.435 1.00 74.54  ? 419 TRP A CH2 1 
ATOM   3307 N  N   . GLN A 1 420 ? 149.234 140.749 141.606 1.00 70.52  ? 420 GLN A N   1 
ATOM   3308 C  CA  . GLN A 1 420 ? 148.991 139.342 141.306 1.00 72.10  ? 420 GLN A CA  1 
ATOM   3309 C  C   . GLN A 1 420 ? 149.762 138.436 142.261 1.00 77.76  ? 420 GLN A C   1 
ATOM   3310 O  O   . GLN A 1 420 ? 149.226 137.440 142.758 1.00 87.85  ? 420 GLN A O   1 
ATOM   3311 C  CB  . GLN A 1 420 ? 149.385 139.046 139.862 1.00 70.60  ? 420 GLN A CB  1 
ATOM   3312 C  CG  . GLN A 1 420 ? 148.399 138.193 139.097 1.00 77.69  ? 420 GLN A CG  1 
ATOM   3313 C  CD  . GLN A 1 420 ? 148.871 137.901 137.690 1.00 83.95  ? 420 GLN A CD  1 
ATOM   3314 O  OE1 . GLN A 1 420 ? 149.498 138.742 137.049 1.00 77.14  ? 420 GLN A OE1 1 
ATOM   3315 N  NE2 . GLN A 1 420 ? 148.571 136.705 137.201 1.00 85.84  ? 420 GLN A NE2 1 
ATOM   3316 N  N   . LEU A 1 421 ? 151.027 138.770 142.522 1.00 67.37  ? 421 LEU A N   1 
ATOM   3317 C  CA  . LEU A 1 421 ? 151.827 137.992 143.461 1.00 66.41  ? 421 LEU A CA  1 
ATOM   3318 C  C   . LEU A 1 421 ? 151.249 138.062 144.868 1.00 71.09  ? 421 LEU A C   1 
ATOM   3319 O  O   . LEU A 1 421 ? 151.213 137.056 145.587 1.00 77.03  ? 421 LEU A O   1 
ATOM   3320 C  CB  . LEU A 1 421 ? 153.270 138.493 143.445 1.00 64.13  ? 421 LEU A CB  1 
ATOM   3321 C  CG  . LEU A 1 421 ? 154.143 137.984 142.301 1.00 72.82  ? 421 LEU A CG  1 
ATOM   3322 C  CD1 . LEU A 1 421 ? 155.473 138.712 142.280 1.00 81.11  ? 421 LEU A CD1 1 
ATOM   3323 C  CD2 . LEU A 1 421 ? 154.354 136.487 142.421 1.00 73.68  ? 421 LEU A CD2 1 
ATOM   3324 N  N   . LEU A 1 422 ? 150.798 139.248 145.281 1.00 69.32  ? 422 LEU A N   1 
ATOM   3325 C  CA  . LEU A 1 422 ? 150.180 139.383 146.598 1.00 68.87  ? 422 LEU A CA  1 
ATOM   3326 C  C   . LEU A 1 422 ? 148.908 138.549 146.697 1.00 70.18  ? 422 LEU A C   1 
ATOM   3327 O  O   . LEU A 1 422 ? 148.652 137.909 147.724 1.00 81.11  ? 422 LEU A O   1 
ATOM   3328 C  CB  . LEU A 1 422 ? 149.890 140.853 146.892 1.00 69.94  ? 422 LEU A CB  1 
ATOM   3329 C  CG  . LEU A 1 422 ? 149.594 141.210 148.350 1.00 77.33  ? 422 LEU A CG  1 
ATOM   3330 C  CD1 . LEU A 1 422 ? 150.567 140.521 149.292 1.00 81.23  ? 422 LEU A CD1 1 
ATOM   3331 C  CD2 . LEU A 1 422 ? 149.628 142.717 148.545 1.00 77.25  ? 422 LEU A CD2 1 
ATOM   3332 N  N   . LEU A 1 423 ? 148.096 138.544 145.636 1.00 71.74  ? 423 LEU A N   1 
ATOM   3333 C  CA  . LEU A 1 423 ? 146.886 137.730 145.629 1.00 74.96  ? 423 LEU A CA  1 
ATOM   3334 C  C   . LEU A 1 423 ? 147.219 136.245 145.686 1.00 79.40  ? 423 LEU A C   1 
ATOM   3335 O  O   . LEU A 1 423 ? 146.517 135.467 146.341 1.00 82.34  ? 423 LEU A O   1 
ATOM   3336 C  CB  . LEU A 1 423 ? 146.049 138.048 144.390 1.00 74.39  ? 423 LEU A CB  1 
ATOM   3337 C  CG  . LEU A 1 423 ? 144.747 137.264 144.220 1.00 70.20  ? 423 LEU A CG  1 
ATOM   3338 C  CD1 . LEU A 1 423 ? 143.843 137.452 145.427 1.00 66.32  ? 423 LEU A CD1 1 
ATOM   3339 C  CD2 . LEU A 1 423 ? 144.038 137.680 142.945 1.00 77.89  ? 423 LEU A CD2 1 
ATOM   3340 N  N   . MET A 1 424 ? 148.281 135.829 144.992 1.00 85.71  ? 424 MET A N   1 
ATOM   3341 C  CA  . MET A 1 424 ? 148.712 134.436 145.064 1.00 82.16  ? 424 MET A CA  1 
ATOM   3342 C  C   . MET A 1 424 ? 149.148 134.062 146.475 1.00 86.81  ? 424 MET A C   1 
ATOM   3343 O  O   . MET A 1 424 ? 148.833 132.970 146.964 1.00 90.06  ? 424 MET A O   1 
ATOM   3344 C  CB  . MET A 1 424 ? 149.843 134.190 144.066 1.00 82.61  ? 424 MET A CB  1 
ATOM   3345 C  CG  . MET A 1 424 ? 150.386 132.777 144.091 1.00 84.57  ? 424 MET A CG  1 
ATOM   3346 S  SD  . MET A 1 424 ? 149.551 131.714 142.905 1.00 109.34 ? 424 MET A SD  1 
ATOM   3347 C  CE  . MET A 1 424 ? 148.734 130.559 144.001 1.00 89.31  ? 424 MET A CE  1 
ATOM   3348 N  N   . VAL A 1 425 ? 149.879 134.954 147.143 1.00 77.96  ? 425 VAL A N   1 
ATOM   3349 C  CA  . VAL A 1 425 ? 150.281 134.701 148.525 1.00 75.01  ? 425 VAL A CA  1 
ATOM   3350 C  C   . VAL A 1 425 ? 149.056 134.602 149.426 1.00 82.95  ? 425 VAL A C   1 
ATOM   3351 O  O   . VAL A 1 425 ? 148.991 133.751 150.323 1.00 86.01  ? 425 VAL A O   1 
ATOM   3352 C  CB  . VAL A 1 425 ? 151.259 135.787 149.006 1.00 80.14  ? 425 VAL A CB  1 
ATOM   3353 C  CG1 . VAL A 1 425 ? 151.528 135.644 150.494 1.00 85.00  ? 425 VAL A CG1 1 
ATOM   3354 C  CG2 . VAL A 1 425 ? 152.559 135.706 148.227 1.00 76.51  ? 425 VAL A CG2 1 
ATOM   3355 N  N   . GLY A 1 426 ? 148.066 135.469 149.206 1.00 85.99  ? 426 GLY A N   1 
ATOM   3356 C  CA  . GLY A 1 426 ? 146.838 135.392 149.981 1.00 81.37  ? 426 GLY A CA  1 
ATOM   3357 C  C   . GLY A 1 426 ? 146.087 134.091 149.765 1.00 81.50  ? 426 GLY A C   1 
ATOM   3358 O  O   . GLY A 1 426 ? 145.551 133.507 150.711 1.00 87.36  ? 426 GLY A O   1 
ATOM   3359 N  N   . LEU A 1 427 ? 146.031 133.622 148.518 1.00 76.03  ? 427 LEU A N   1 
ATOM   3360 C  CA  . LEU A 1 427 ? 145.423 132.331 148.225 1.00 74.78  ? 427 LEU A CA  1 
ATOM   3361 C  C   . LEU A 1 427 ? 146.163 131.176 148.882 1.00 77.00  ? 427 LEU A C   1 
ATOM   3362 O  O   . LEU A 1 427 ? 145.520 130.247 149.382 1.00 82.10  ? 427 LEU A O   1 
ATOM   3363 C  CB  . LEU A 1 427 ? 145.354 132.110 146.716 1.00 70.61  ? 427 LEU A CB  1 
ATOM   3364 C  CG  . LEU A 1 427 ? 144.226 132.853 146.000 1.00 68.76  ? 427 LEU A CG  1 
ATOM   3365 C  CD1 . LEU A 1 427 ? 144.552 133.037 144.531 1.00 70.22  ? 427 LEU A CD1 1 
ATOM   3366 C  CD2 . LEU A 1 427 ? 142.910 132.117 146.174 1.00 70.04  ? 427 LEU A CD2 1 
ATOM   3367 N  N   . LEU A 1 428 ? 147.474 131.215 148.943 1.00 78.02  ? 428 LEU A N   1 
ATOM   3368 C  CA  . LEU A 1 428 ? 148.225 130.170 149.657 1.00 75.48  ? 428 LEU A CA  1 
ATOM   3369 C  C   . LEU A 1 428 ? 147.978 130.235 151.159 1.00 79.03  ? 428 LEU A C   1 
ATOM   3370 O  O   . LEU A 1 428 ? 147.986 129.212 151.800 1.00 83.08  ? 428 LEU A O   1 
ATOM   3371 C  CB  . LEU A 1 428 ? 149.699 130.316 149.323 1.00 80.58  ? 428 LEU A CB  1 
ATOM   3372 C  CG  . LEU A 1 428 ? 150.088 129.918 147.900 1.00 77.86  ? 428 LEU A CG  1 
ATOM   3373 C  CD1 . LEU A 1 428 ? 151.583 130.063 147.667 1.00 81.15  ? 428 LEU A CD1 1 
ATOM   3374 C  CD2 . LEU A 1 428 ? 149.619 128.511 147.564 1.00 73.49  ? 428 LEU A CD2 1 
ATOM   3375 N  N   . LEU A 1 429 ? 147.856 131.446 151.681 1.00 78.06  ? 429 LEU A N   1 
ATOM   3376 C  CA  . LEU A 1 429 ? 147.507 131.567 153.093 1.00 76.57  ? 429 LEU A CA  1 
ATOM   3377 C  C   . LEU A 1 429 ? 146.137 130.960 153.370 1.00 79.29  ? 429 LEU A C   1 
ATOM   3378 O  O   . LEU A 1 429 ? 145.941 130.262 154.373 1.00 87.54  ? 429 LEU A O   1 
ATOM   3379 C  CB  . LEU A 1 429 ? 147.539 133.038 153.512 1.00 72.86  ? 429 LEU A CB  1 
ATOM   3380 C  CG  . LEU A 1 429 ? 146.951 133.401 154.877 1.00 72.71  ? 429 LEU A CG  1 
ATOM   3381 C  CD1 . LEU A 1 429 ? 147.624 132.615 155.993 1.00 79.18  ? 429 LEU A CD1 1 
ATOM   3382 C  CD2 . LEU A 1 429 ? 147.062 134.893 155.128 1.00 79.80  ? 429 LEU A CD2 1 
ATOM   3383 N  N   . TRP A 1 430 ? 145.171 131.224 152.487 1.00 75.07  ? 430 TRP A N   1 
ATOM   3384 C  CA  . TRP A 1 430 ? 143.844 130.630 152.631 1.00 76.83  ? 430 TRP A CA  1 
ATOM   3385 C  C   . TRP A 1 430 ? 143.916 129.110 152.559 1.00 77.61  ? 430 TRP A C   1 
ATOM   3386 O  O   . TRP A 1 430 ? 143.262 128.410 153.342 1.00 82.94  ? 430 TRP A O   1 
ATOM   3387 C  CB  . TRP A 1 430 ? 142.909 131.172 151.550 1.00 70.33  ? 430 TRP A CB  1 
ATOM   3388 C  CG  . TRP A 1 430 ? 141.559 130.514 151.514 1.00 73.14  ? 430 TRP A CG  1 
ATOM   3389 C  CD1 . TRP A 1 430 ? 140.450 130.885 152.211 1.00 81.64  ? 430 TRP A CD1 1 
ATOM   3390 C  CD2 . TRP A 1 430 ? 141.179 129.373 150.734 1.00 72.80  ? 430 TRP A CD2 1 
ATOM   3391 N  NE1 . TRP A 1 430 ? 139.404 130.047 151.918 1.00 81.64  ? 430 TRP A NE1 1 
ATOM   3392 C  CE2 . TRP A 1 430 ? 139.825 129.109 151.015 1.00 77.19  ? 430 TRP A CE2 1 
ATOM   3393 C  CE3 . TRP A 1 430 ? 141.853 128.548 149.829 1.00 76.95  ? 430 TRP A CE3 1 
ATOM   3394 C  CZ2 . TRP A 1 430 ? 139.131 128.058 150.422 1.00 74.71  ? 430 TRP A CZ2 1 
ATOM   3395 C  CZ3 . TRP A 1 430 ? 141.163 127.503 149.244 1.00 79.54  ? 430 TRP A CZ3 1 
ATOM   3396 C  CH2 . TRP A 1 430 ? 139.817 127.267 149.542 1.00 75.80  ? 430 TRP A CH2 1 
ATOM   3397 N  N   . LEU A 1 431 ? 144.685 128.538 151.683 1.00 77.66  ? 431 LEU A N   1 
ATOM   3398 C  CA  . LEU A 1 431 ? 144.820 127.080 151.577 1.00 76.74  ? 431 LEU A CA  1 
ATOM   3399 C  C   . LEU A 1 431 ? 145.485 126.486 152.811 1.00 77.53  ? 431 LEU A C   1 
ATOM   3400 O  O   . LEU A 1 431 ? 145.105 125.435 153.217 1.00 86.09  ? 431 LEU A O   1 
ATOM   3401 C  CB  . LEU A 1 431 ? 145.608 126.783 150.308 1.00 75.41  ? 431 LEU A CB  1 
ATOM   3402 C  CG  . LEU A 1 431 ? 145.880 125.297 150.047 1.00 67.35  ? 431 LEU A CG  1 
ATOM   3403 C  CD1 . LEU A 1 431 ? 144.589 124.506 149.917 1.00 70.30  ? 431 LEU A CD1 1 
ATOM   3404 C  CD2 . LEU A 1 431 ? 146.769 125.081 148.833 1.00 74.11  ? 431 LEU A CD2 1 
ATOM   3405 N  N   . PHE A 1 432 ? 146.471 127.196 153.325 1.00 79.02  ? 432 PHE A N   1 
ATOM   3406 C  CA  . PHE A 1 432 ? 147.065 126.713 154.566 1.00 79.26  ? 432 PHE A CA  1 
ATOM   3407 C  C   . PHE A 1 432 ? 146.053 126.722 155.705 1.00 77.47  ? 432 PHE A C   1 
ATOM   3408 O  O   . PHE A 1 432 ? 145.947 125.755 156.471 1.00 87.57  ? 432 PHE A O   1 
ATOM   3409 C  CB  . PHE A 1 432 ? 148.282 127.561 154.934 1.00 82.29  ? 432 PHE A CB  1 
ATOM   3410 C  CG  . PHE A 1 432 ? 148.719 127.399 156.362 1.00 81.16  ? 432 PHE A CG  1 
ATOM   3411 C  CD1 . PHE A 1 432 ? 149.299 126.221 156.794 1.00 83.79  ? 432 PHE A CD1 1 
ATOM   3412 C  CD2 . PHE A 1 432 ? 148.532 128.421 157.275 1.00 81.47  ? 432 PHE A CD2 1 
ATOM   3413 C  CE1 . PHE A 1 432 ? 149.697 126.069 158.106 1.00 82.09  ? 432 PHE A CE1 1 
ATOM   3414 C  CE2 . PHE A 1 432 ? 148.925 128.275 158.588 1.00 83.30  ? 432 PHE A CE2 1 
ATOM   3415 C  CZ  . PHE A 1 432 ? 149.510 127.098 159.004 1.00 83.05  ? 432 PHE A CZ  1 
ATOM   3416 N  N   . LEU A 1 433 ? 145.308 127.822 155.839 1.00 80.83  ? 433 LEU A N   1 
ATOM   3417 C  CA  . LEU A 1 433 ? 144.288 127.919 156.874 1.00 86.79  ? 433 LEU A CA  1 
ATOM   3418 C  C   . LEU A 1 433 ? 143.223 126.847 156.721 1.00 87.85  ? 433 LEU A C   1 
ATOM   3419 O  O   . LEU A 1 433 ? 142.677 126.379 157.725 1.00 88.13  ? 433 LEU A O   1 
ATOM   3420 C  CB  . LEU A 1 433 ? 143.632 129.299 156.840 1.00 79.58  ? 433 LEU A CB  1 
ATOM   3421 C  CG  . LEU A 1 433 ? 144.386 130.485 157.438 1.00 84.68  ? 433 LEU A CG  1 
ATOM   3422 C  CD1 . LEU A 1 433 ? 143.703 131.782 157.042 1.00 82.94  ? 433 LEU A CD1 1 
ATOM   3423 C  CD2 . LEU A 1 433 ? 144.482 130.364 158.948 1.00 84.63  ? 433 LEU A CD2 1 
ATOM   3424 N  N   . MET A 1 434 ? 142.832 126.416 155.521 1.00 85.49  ? 434 MET A N   1 
ATOM   3425 C  CA  . MET A 1 434 ? 141.859 125.332 155.253 1.00 84.04  ? 434 MET A CA  1 
ATOM   3426 C  C   . MET A 1 434 ? 142.451 123.961 155.545 1.00 85.38  ? 434 MET A C   1 
ATOM   3427 O  O   . MET A 1 434 ? 141.839 123.163 156.228 1.00 87.58  ? 434 MET A O   1 
ATOM   3428 C  CB  . MET A 1 434 ? 141.467 125.308 153.773 1.00 85.08  ? 434 MET A CB  1 
ATOM   3429 C  CG  . MET A 1 434 ? 140.857 126.578 153.237 1.00 91.55  ? 434 MET A CG  1 
ATOM   3430 S  SD  . MET A 1 434 ? 139.183 126.847 153.825 1.00 108.26 ? 434 MET A SD  1 
ATOM   3431 C  CE  . MET A 1 434 ? 138.404 125.312 153.337 1.00 84.71  ? 434 MET A CE  1 
ATOM   3432 N  N   . LEU A 1 435 ? 143.677 123.789 155.097 1.00 81.41  ? 435 LEU A N   1 
ATOM   3433 C  CA  . LEU A 1 435 ? 144.288 122.475 155.243 1.00 79.84  ? 435 LEU A CA  1 
ATOM   3434 C  C   . LEU A 1 435 ? 144.684 122.153 156.676 1.00 86.42  ? 435 LEU A C   1 
ATOM   3435 O  O   . LEU A 1 435 ? 144.704 120.974 157.040 1.00 93.67  ? 435 LEU A O   1 
ATOM   3436 C  CB  . LEU A 1 435 ? 145.521 122.363 154.345 1.00 81.08  ? 435 LEU A CB  1 
ATOM   3437 C  CG  . LEU A 1 435 ? 145.284 122.160 152.848 1.00 83.40  ? 435 LEU A CG  1 
ATOM   3438 C  CD1 . LEU A 1 435 ? 146.557 121.681 152.175 1.00 87.87  ? 435 LEU A CD1 1 
ATOM   3439 C  CD2 . LEU A 1 435 ? 144.155 121.176 152.605 1.00 83.84  ? 435 LEU A CD2 1 
ATOM   3440 N  N   . ARG A 1 436 ? 145.005 123.155 157.495 1.00 89.09  ? 436 ARG A N   1 
ATOM   3441 C  CA  . ARG A 1 436 ? 145.374 122.874 158.877 1.00 89.53  ? 436 ARG A CA  1 
ATOM   3442 C  C   . ARG A 1 436 ? 144.206 122.359 159.707 1.00 89.63  ? 436 ARG A C   1 
ATOM   3443 O  O   . ARG A 1 436 ? 144.427 121.874 160.821 1.00 90.70  ? 436 ARG A O   1 
ATOM   3444 C  CB  . ARG A 1 436 ? 145.959 124.124 159.539 1.00 93.56  ? 436 ARG A CB  1 
ATOM   3445 C  CG  . ARG A 1 436 ? 145.004 125.295 159.597 1.00 91.48  ? 436 ARG A CG  1 
ATOM   3446 C  CD  . ARG A 1 436 ? 145.703 126.568 160.030 1.00 91.23  ? 436 ARG A CD  1 
ATOM   3447 N  NE  . ARG A 1 436 ? 146.576 126.363 161.178 1.00 94.79  ? 436 ARG A NE  1 
ATOM   3448 C  CZ  . ARG A 1 436 ? 146.608 127.154 162.240 1.00 94.64  ? 436 ARG A CZ  1 
ATOM   3449 N  NH1 . ARG A 1 436 ? 145.817 128.210 162.339 1.00 95.12  ? 436 ARG A NH1 1 
ATOM   3450 N  NH2 . ARG A 1 436 ? 147.455 126.881 163.228 1.00 93.14  ? 436 ARG A NH2 1 
ATOM   3451 N  N   . CYS A 1 437 ? 142.979 122.452 159.196 1.00 93.75  ? 437 CYS A N   1 
ATOM   3452 C  CA  . CYS A 1 437 ? 141.799 121.982 159.907 1.00 95.86  ? 437 CYS A CA  1 
ATOM   3453 C  C   . CYS A 1 437 ? 141.414 120.549 159.564 1.00 97.80  ? 437 CYS A C   1 
ATOM   3454 O  O   . CYS A 1 437 ? 140.470 120.022 160.160 1.00 102.80 ? 437 CYS A O   1 
ATOM   3455 C  CB  . CYS A 1 437 ? 140.606 122.899 159.613 1.00 92.28  ? 437 CYS A CB  1 
ATOM   3456 S  SG  . CYS A 1 437 ? 140.723 124.537 160.356 1.00 100.82 ? 437 CYS A SG  1 
ATOM   3457 N  N   . THR A 1 438 ? 142.147 119.928 158.647 1.00 97.61  ? 438 THR A N   1 
ATOM   3458 C  CA  . THR A 1 438 ? 141.855 118.582 158.115 1.00 96.54  ? 438 THR A CA  1 
ATOM   3459 C  C   . THR A 1 438 ? 142.751 117.515 158.737 1.00 100.02 ? 438 THR A C   1 
ATOM   3460 O  O   . THR A 1 438 ? 142.429 116.357 158.601 1.00 103.98 ? 438 THR A O   1 
ATOM   3461 C  CB  . THR A 1 438 ? 142.002 118.642 156.586 1.00 98.08  ? 438 THR A CB  1 
ATOM   3462 O  OG1 . THR A 1 438 ? 143.375 118.872 156.283 1.00 101.42 ? 438 THR A OG1 1 
ATOM   3463 C  CG2 . THR A 1 438 ? 141.143 119.702 155.931 1.00 99.84  ? 438 THR A CG2 1 
ATOM   3464 N  N   . VAL A 1 439 ? 143.800 117.903 159.432 1.00 97.26  ? 439 VAL A N   1 
ATOM   3465 C  CA  . VAL A 1 439 ? 144.790 116.938 159.900 1.00 98.38  ? 439 VAL A CA  1 
ATOM   3466 C  C   . VAL A 1 439 ? 144.171 115.991 160.922 1.00 102.70 ? 439 VAL A C   1 
ATOM   3467 O  O   . VAL A 1 439 ? 144.342 114.768 160.841 1.00 106.07 ? 439 VAL A O   1 
ATOM   3468 C  CB  . VAL A 1 439 ? 146.016 117.670 160.473 1.00 98.50  ? 439 VAL A CB  1 
ATOM   3469 C  CG1 . VAL A 1 439 ? 146.840 116.739 161.346 1.00 100.64 ? 439 VAL A CG1 1 
ATOM   3470 C  CG2 . VAL A 1 439 ? 146.861 118.245 159.350 1.00 103.35 ? 439 VAL A CG2 1 
ATOM   3471 N  N   . SER A 1 440 ? 143.438 116.539 161.893 1.00 108.10 ? 440 SER A N   1 
ATOM   3472 C  CA  . SER A 1 440 ? 142.801 115.699 162.902 1.00 109.90 ? 440 SER A CA  1 
ATOM   3473 C  C   . SER A 1 440 ? 141.740 114.800 162.283 1.00 107.99 ? 440 SER A C   1 
ATOM   3474 O  O   . SER A 1 440 ? 141.600 113.634 162.671 1.00 113.11 ? 440 SER A O   1 
ATOM   3475 C  CB  . SER A 1 440 ? 142.187 116.567 163.998 1.00 112.46 ? 440 SER A CB  1 
ATOM   3476 O  OG  . SER A 1 440 ? 141.087 117.307 163.503 1.00 111.34 ? 440 SER A OG  1 
ATOM   3477 N  N   . ALA A 1 441 ? 140.975 115.328 161.324 1.00 97.81  ? 441 ALA A N   1 
ATOM   3478 C  CA  . ALA A 1 441 ? 139.948 114.527 160.668 1.00 102.73 ? 441 ALA A CA  1 
ATOM   3479 C  C   . ALA A 1 441 ? 140.562 113.358 159.910 1.00 107.71 ? 441 ALA A C   1 
ATOM   3480 O  O   . ALA A 1 441 ? 140.021 112.246 159.926 1.00 108.01 ? 441 ALA A O   1 
ATOM   3481 C  CB  . ALA A 1 441 ? 139.120 115.401 159.730 1.00 99.96  ? 441 ALA A CB  1 
ATOM   3482 N  N   . PHE A 1 442 ? 141.689 113.590 159.235 1.00 107.36 ? 442 PHE A N   1 
ATOM   3483 C  CA  . PHE A 1 442 ? 142.377 112.494 158.561 1.00 102.71 ? 442 PHE A CA  1 
ATOM   3484 C  C   . PHE A 1 442 ? 142.964 111.505 159.559 1.00 107.06 ? 442 PHE A C   1 
ATOM   3485 O  O   . PHE A 1 442 ? 142.964 110.296 159.304 1.00 109.16 ? 442 PHE A O   1 
ATOM   3486 C  CB  . PHE A 1 442 ? 143.470 113.040 157.644 1.00 100.95 ? 442 PHE A CB  1 
ATOM   3487 C  CG  . PHE A 1 442 ? 142.974 113.445 156.287 1.00 104.01 ? 442 PHE A CG  1 
ATOM   3488 C  CD1 . PHE A 1 442 ? 142.335 112.533 155.468 1.00 106.33 ? 442 PHE A CD1 1 
ATOM   3489 C  CD2 . PHE A 1 442 ? 143.147 114.740 155.829 1.00 105.22 ? 442 PHE A CD2 1 
ATOM   3490 C  CE1 . PHE A 1 442 ? 141.877 112.903 154.220 1.00 107.95 ? 442 PHE A CE1 1 
ATOM   3491 C  CE2 . PHE A 1 442 ? 142.692 115.114 154.584 1.00 104.93 ? 442 PHE A CE2 1 
ATOM   3492 C  CZ  . PHE A 1 442 ? 142.056 114.195 153.778 1.00 105.58 ? 442 PHE A CZ  1 
ATOM   3493 N  N   . LYS A 1 443 ? 143.468 111.992 160.692 1.00 115.42 ? 443 LYS A N   1 
ATOM   3494 C  CA  . LYS A 1 443 ? 144.079 111.121 161.688 1.00 113.09 ? 443 LYS A CA  1 
ATOM   3495 C  C   . LYS A 1 443 ? 143.036 110.492 162.601 1.00 112.99 ? 443 LYS A C   1 
ATOM   3496 O  O   . LYS A 1 443 ? 143.142 110.586 163.828 1.00 115.53 ? 443 LYS A O   1 
ATOM   3497 C  CB  . LYS A 1 443 ? 145.099 111.898 162.524 1.00 113.93 ? 443 LYS A CB  1 
ATOM   3498 C  CG  . LYS A 1 443 ? 146.507 111.897 161.949 1.00 117.90 ? 443 LYS A CG  1 
ATOM   3499 C  CD  . LYS A 1 443 ? 147.371 113.001 162.547 1.00 117.24 ? 443 LYS A CD  1 
ATOM   3500 C  CE  . LYS A 1 443 ? 146.912 113.395 163.944 1.00 116.45 ? 443 LYS A CE  1 
ATOM   3501 N  NZ  . LYS A 1 443 ? 147.131 114.841 164.218 1.00 114.63 ? 443 LYS A NZ  1 
ATOM   3502 N  N   . GLU A 1 444 ? 142.026 109.848 162.017 1.00 123.83 ? 444 GLU A N   1 
ATOM   3503 C  CA  . GLU A 1 444 ? 141.001 109.169 162.801 1.00 124.76 ? 444 GLU A CA  1 
ATOM   3504 C  C   . GLU A 1 444 ? 140.971 107.684 162.471 1.00 131.01 ? 444 GLU A C   1 
ATOM   3505 O  O   . GLU A 1 444 ? 141.717 107.220 161.604 1.00 134.32 ? 444 GLU A O   1 
ATOM   3506 C  CB  . GLU A 1 444 ? 139.628 109.793 162.557 1.00 121.73 ? 444 GLU A CB  1 
ATOM   3507 C  CG  . GLU A 1 444 ? 139.396 111.090 163.307 1.00 125.12 ? 444 GLU A CG  1 
ATOM   3508 C  CD  . GLU A 1 444 ? 137.925 111.405 163.477 1.00 128.75 ? 444 GLU A CD  1 
ATOM   3509 O  OE1 . GLU A 1 444 ? 137.090 110.518 163.207 1.00 131.06 ? 444 GLU A OE1 1 
ATOM   3510 O  OE2 . GLU A 1 444 ? 137.602 112.542 163.881 1.00 128.49 ? 444 GLU A OE2 1 
ATOM   3511 N  N   . LYS A 1 445 ? 140.110 106.931 163.153 1.00 135.04 ? 445 LYS A N   1 
ATOM   3512 C  CA  . LYS A 1 445 ? 140.019 105.493 162.960 1.00 135.11 ? 445 LYS A CA  1 
ATOM   3513 C  C   . LYS A 1 445 ? 138.587 105.112 162.617 1.00 134.47 ? 445 LYS A C   1 
ATOM   3514 O  O   . LYS A 1 445 ? 137.632 105.623 163.208 1.00 133.60 ? 445 LYS A O   1 
ATOM   3515 C  CB  . LYS A 1 445 ? 140.478 104.726 164.209 1.00 132.18 ? 445 LYS A CB  1 
ATOM   3516 C  CG  . LYS A 1 445 ? 141.980 104.481 164.287 1.00 131.80 ? 445 LYS A CG  1 
ATOM   3517 C  CD  . LYS A 1 445 ? 142.628 104.467 162.909 1.00 133.25 ? 445 LYS A CD  1 
ATOM   3518 C  CE  . LYS A 1 445 ? 144.144 104.417 163.014 1.00 134.76 ? 445 LYS A CE  1 
ATOM   3519 N  NZ  . LYS A 1 445 ? 144.806 104.938 161.785 1.00 134.77 ? 445 LYS A NZ  1 
ATOM   3520 N  N   . GLY A 1 446 ? 138.448 104.210 161.655 1.00 136.24 ? 446 GLY A N   1 
ATOM   3521 C  CA  . GLY A 1 446 ? 137.136 103.679 161.290 1.00 135.30 ? 446 GLY A CA  1 
ATOM   3522 C  C   . GLY A 1 446 ? 136.311 104.449 160.282 1.00 136.99 ? 446 GLY A C   1 
ATOM   3523 O  O   . GLY A 1 446 ? 135.686 103.845 159.405 1.00 137.13 ? 446 GLY A O   1 
ATOM   3524 N  N   . VAL A 1 447 ? 136.289 105.777 160.386 1.00 133.95 ? 447 VAL A N   1 
ATOM   3525 C  CA  . VAL A 1 447 ? 135.448 106.585 159.515 1.00 131.98 ? 447 VAL A CA  1 
ATOM   3526 C  C   . VAL A 1 447 ? 136.043 106.623 158.113 1.00 132.78 ? 447 VAL A C   1 
ATOM   3527 O  O   . VAL A 1 447 ? 137.257 106.791 157.940 1.00 132.94 ? 447 VAL A O   1 
ATOM   3528 C  CB  . VAL A 1 447 ? 135.277 107.997 160.097 1.00 130.13 ? 447 VAL A CB  1 
ATOM   3529 C  CG1 . VAL A 1 447 ? 136.619 108.565 160.524 1.00 130.65 ? 447 VAL A CG1 1 
ATOM   3530 C  CG2 . VAL A 1 447 ? 134.597 108.914 159.095 1.00 129.58 ? 447 VAL A CG2 1 
ATOM   3531 N  N   . ASP A 1 448 ? 135.190 106.445 157.106 1.00 127.20 ? 448 ASP A N   1 
ATOM   3532 C  CA  . ASP A 1 448 ? 135.623 106.555 155.719 1.00 126.55 ? 448 ASP A CA  1 
ATOM   3533 C  C   . ASP A 1 448 ? 136.064 107.983 155.416 1.00 128.06 ? 448 ASP A C   1 
ATOM   3534 O  O   . ASP A 1 448 ? 135.461 108.950 155.888 1.00 132.33 ? 448 ASP A O   1 
ATOM   3535 C  CB  . ASP A 1 448 ? 134.490 106.133 154.784 1.00 124.71 ? 448 ASP A CB  1 
ATOM   3536 C  CG  . ASP A 1 448 ? 134.832 106.328 153.322 1.00 128.04 ? 448 ASP A CG  1 
ATOM   3537 O  OD1 . ASP A 1 448 ? 135.409 105.400 152.718 1.00 130.44 ? 448 ASP A OD1 1 
ATOM   3538 O  OD2 . ASP A 1 448 ? 134.518 107.404 152.775 1.00 129.17 ? 448 ASP A OD2 1 
ATOM   3539 N  N   . LYS A 1 449 ? 137.126 108.114 154.616 1.00 106.39 ? 449 LYS A N   1 
ATOM   3540 C  CA  . LYS A 1 449 ? 137.768 109.406 154.397 1.00 105.89 ? 449 LYS A CA  1 
ATOM   3541 C  C   . LYS A 1 449 ? 137.808 109.786 152.921 1.00 107.25 ? 449 LYS A C   1 
ATOM   3542 O  O   . LYS A 1 449 ? 138.571 110.671 152.529 1.00 112.55 ? 449 LYS A O   1 
ATOM   3543 C  CB  . LYS A 1 449 ? 139.178 109.413 154.983 1.00 106.16 ? 449 LYS A CB  1 
ATOM   3544 C  CG  . LYS A 1 449 ? 139.229 109.671 156.477 1.00 106.05 ? 449 LYS A CG  1 
ATOM   3545 C  CD  . LYS A 1 449 ? 140.177 108.711 157.169 1.00 108.02 ? 449 LYS A CD  1 
ATOM   3546 C  CE  . LYS A 1 449 ? 139.880 108.619 158.653 1.00 112.00 ? 449 LYS A CE  1 
ATOM   3547 N  NZ  . LYS A 1 449 ? 140.507 107.418 159.262 1.00 111.33 ? 449 LYS A NZ  1 
ATOM   3548 N  N   . ASN A 1 450 ? 136.991 109.143 152.090 1.00 105.82 ? 450 ASN A N   1 
ATOM   3549 C  CA  . ASN A 1 450 ? 137.021 109.429 150.658 1.00 108.84 ? 450 ASN A CA  1 
ATOM   3550 C  C   . ASN A 1 450 ? 136.388 110.776 150.329 1.00 110.00 ? 450 ASN A C   1 
ATOM   3551 O  O   . ASN A 1 450 ? 136.923 111.532 149.508 1.00 115.79 ? 450 ASN A O   1 
ATOM   3552 C  CB  . ASN A 1 450 ? 136.328 108.301 149.895 1.00 107.56 ? 450 ASN A CB  1 
ATOM   3553 C  CG  . ASN A 1 450 ? 137.098 107.003 149.961 1.00 114.80 ? 450 ASN A CG  1 
ATOM   3554 O  OD1 . ASN A 1 450 ? 138.190 106.889 149.407 1.00 117.57 ? 450 ASN A OD1 1 
ATOM   3555 N  ND2 . ASN A 1 450 ? 136.545 106.022 150.660 1.00 114.79 ? 450 ASN A ND2 1 
ATOM   3556 N  N   . LEU A 1 451 ? 135.248 111.090 150.950 1.00 97.71  ? 451 LEU A N   1 
ATOM   3557 C  CA  . LEU A 1 451 ? 134.636 112.398 150.745 1.00 103.91 ? 451 LEU A CA  1 
ATOM   3558 C  C   . LEU A 1 451 ? 135.537 113.516 151.254 1.00 107.24 ? 451 LEU A C   1 
ATOM   3559 O  O   . LEU A 1 451 ? 135.684 114.547 150.589 1.00 107.52 ? 451 LEU A O   1 
ATOM   3560 C  CB  . LEU A 1 451 ? 133.273 112.447 151.435 1.00 97.70  ? 451 LEU A CB  1 
ATOM   3561 C  CG  . LEU A 1 451 ? 132.401 113.674 151.168 1.00 100.55 ? 451 LEU A CG  1 
ATOM   3562 C  CD1 . LEU A 1 451 ? 132.024 113.755 149.698 1.00 99.63  ? 451 LEU A CD1 1 
ATOM   3563 C  CD2 . LEU A 1 451 ? 131.158 113.639 152.039 1.00 99.42  ? 451 LEU A CD2 1 
ATOM   3564 N  N   . LEU A 1 452 ? 136.119 113.363 152.448 1.00 98.61  ? 452 LEU A N   1 
ATOM   3565 C  CA  . LEU A 1 452 ? 137.123 114.334 152.944 1.00 95.52  ? 452 LEU A CA  1 
ATOM   3566 C  C   . LEU A 1 452 ? 138.255 114.446 151.925 1.00 101.64 ? 452 LEU A C   1 
ATOM   3567 O  O   . LEU A 1 452 ? 138.579 115.564 151.602 1.00 103.96 ? 452 LEU A O   1 
ATOM   3568 C  CB  . LEU A 1 452 ? 137.639 113.923 154.327 1.00 96.96  ? 452 LEU A CB  1 
ATOM   3569 C  CG  . LEU A 1 452 ? 138.773 114.746 154.925 1.00 100.11 ? 452 LEU A CG  1 
ATOM   3570 C  CD1 . LEU A 1 452 ? 138.330 116.166 155.215 1.00 101.19 ? 452 LEU A CD1 1 
ATOM   3571 C  CD2 . LEU A 1 452 ? 139.296 114.080 156.187 1.00 99.89  ? 452 LEU A CD2 1 
ATOM   3572 N  N   . ALA A 1 453 ? 138.784 113.328 151.410 1.00 99.59  ? 453 ALA A N   1 
ATOM   3573 C  CA  . ALA A 1 453 ? 139.919 113.390 150.495 1.00 95.02  ? 453 ALA A CA  1 
ATOM   3574 C  C   . ALA A 1 453 ? 139.579 114.180 149.238 1.00 98.02  ? 453 ALA A C   1 
ATOM   3575 O  O   . ALA A 1 453 ? 140.377 115.009 148.785 1.00 107.21 ? 453 ALA A O   1 
ATOM   3576 C  CB  . ALA A 1 453 ? 140.377 111.977 150.135 1.00 95.10  ? 453 ALA A CB  1 
ATOM   3577 N  N   . ILE A 1 454 ? 138.413 113.950 148.665 1.00 89.02  ? 454 ILE A N   1 
ATOM   3578 C  CA  . ILE A 1 454 ? 137.974 114.679 147.451 1.00 93.26  ? 454 ILE A CA  1 
ATOM   3579 C  C   . ILE A 1 454 ? 137.719 116.156 147.764 1.00 96.71  ? 454 ILE A C   1 
ATOM   3580 O  O   . ILE A 1 454 ? 137.975 116.979 146.918 1.00 103.48 ? 454 ILE A O   1 
ATOM   3581 C  CB  . ILE A 1 454 ? 136.793 113.994 146.718 1.00 87.89  ? 454 ILE A CB  1 
ATOM   3582 C  CG1 . ILE A 1 454 ? 136.661 114.492 145.275 1.00 93.89  ? 454 ILE A CG1 1 
ATOM   3583 C  CG2 . ILE A 1 454 ? 135.476 114.134 147.459 1.00 87.79  ? 454 ILE A CG2 1 
ATOM   3584 C  CD1 . ILE A 1 454 ? 137.949 114.518 144.494 1.00 93.68  ? 454 ILE A CD1 1 
ATOM   3585 N  N   . PHE A 1 455 ? 137.224 116.452 148.946 1.00 84.49  ? 455 PHE A N   1 
ATOM   3586 C  CA  . PHE A 1 455 ? 137.050 117.842 149.356 1.00 86.63  ? 455 PHE A CA  1 
ATOM   3587 C  C   . PHE A 1 455 ? 138.394 118.546 149.516 1.00 94.00  ? 455 PHE A C   1 
ATOM   3588 O  O   . PHE A 1 455 ? 138.557 119.698 149.093 1.00 92.08  ? 455 PHE A O   1 
ATOM   3589 C  CB  . PHE A 1 455 ? 136.243 117.893 150.654 1.00 83.19  ? 455 PHE A CB  1 
ATOM   3590 C  CG  . PHE A 1 455 ? 135.649 119.237 150.960 1.00 85.37  ? 455 PHE A CG  1 
ATOM   3591 C  CD1 . PHE A 1 455 ? 135.515 120.197 149.973 1.00 87.45  ? 455 PHE A CD1 1 
ATOM   3592 C  CD2 . PHE A 1 455 ? 135.205 119.533 152.237 1.00 85.92  ? 455 PHE A CD2 1 
ATOM   3593 C  CE1 . PHE A 1 455 ? 134.962 121.429 150.256 1.00 89.63  ? 455 PHE A CE1 1 
ATOM   3594 C  CE2 . PHE A 1 455 ? 134.653 120.764 152.524 1.00 86.13  ? 455 PHE A CE2 1 
ATOM   3595 C  CZ  . PHE A 1 455 ? 134.531 121.712 151.533 1.00 86.70  ? 455 PHE A CZ  1 
ATOM   3596 N  N   . VAL A 1 456 ? 139.375 117.864 150.110 1.00 94.41  ? 456 VAL A N   1 
ATOM   3597 C  CA  . VAL A 1 456 ? 140.696 118.456 150.312 1.00 84.19  ? 456 VAL A CA  1 
ATOM   3598 C  C   . VAL A 1 456 ? 141.404 118.653 148.975 1.00 85.65  ? 456 VAL A C   1 
ATOM   3599 O  O   . VAL A 1 456 ? 142.100 119.653 148.758 1.00 93.89  ? 456 VAL A O   1 
ATOM   3600 C  CB  . VAL A 1 456 ? 141.529 117.587 151.271 1.00 86.97  ? 456 VAL A CB  1 
ATOM   3601 C  CG1 . VAL A 1 456 ? 143.002 117.952 151.198 1.00 88.45  ? 456 VAL A CG1 1 
ATOM   3602 C  CG2 . VAL A 1 456 ? 141.015 117.741 152.691 1.00 86.84  ? 456 VAL A CG2 1 
ATOM   3603 N  N   . ALA A 1 457 ? 141.247 117.692 148.061 1.00 85.62  ? 457 ALA A N   1 
ATOM   3604 C  CA  . ALA A 1 457 ? 141.829 117.845 146.731 1.00 90.81  ? 457 ALA A CA  1 
ATOM   3605 C  C   . ALA A 1 457 ? 141.240 119.054 146.017 1.00 92.60  ? 457 ALA A C   1 
ATOM   3606 O  O   . ALA A 1 457 ? 141.958 119.810 145.349 1.00 101.43 ? 457 ALA A O   1 
ATOM   3607 C  CB  . ALA A 1 457 ? 141.610 116.573 145.912 1.00 84.38  ? 457 ALA A CB  1 
ATOM   3608 N  N   . SER A 1 458 ? 139.937 119.326 146.138 1.00 79.72  ? 458 SER A N   1 
ATOM   3609 C  CA  . SER A 1 458 ? 139.248 120.504 145.539 1.00 85.76  ? 458 SER A CA  1 
ATOM   3610 C  C   . SER A 1 458 ? 139.680 121.798 146.265 1.00 88.47  ? 458 SER A C   1 
ATOM   3611 O  O   . SER A 1 458 ? 139.632 122.856 145.623 1.00 88.31  ? 458 SER A O   1 
ATOM   3612 C  CB  . SER A 1 458 ? 137.742 120.322 145.467 1.00 88.82  ? 458 SER A CB  1 
ATOM   3613 O  OG  . SER A 1 458 ? 137.053 121.170 146.357 1.00 93.51  ? 458 SER A OG  1 
ATOM   3614 N  N   . MET A 1 459 ? 140.034 121.693 147.554 1.00 86.79  ? 459 MET A N   1 
ATOM   3615 C  CA  . MET A 1 459 ? 140.652 122.827 148.235 1.00 82.06  ? 459 MET A CA  1 
ATOM   3616 C  C   . MET A 1 459 ? 142.003 123.160 147.628 1.00 84.99  ? 459 MET A C   1 
ATOM   3617 O  O   . MET A 1 459 ? 142.307 124.329 147.363 1.00 89.77  ? 459 MET A O   1 
ATOM   3618 C  CB  . MET A 1 459 ? 140.845 122.523 149.718 1.00 85.06  ? 459 MET A CB  1 
ATOM   3619 C  CG  . MET A 1 459 ? 139.664 122.788 150.595 1.00 97.40  ? 459 MET A CG  1 
ATOM   3620 S  SD  . MET A 1 459 ? 139.850 121.932 152.170 1.00 106.73 ? 459 MET A SD  1 
ATOM   3621 C  CE  . MET A 1 459 ? 138.279 121.097 152.292 1.00 91.75  ? 459 MET A CE  1 
ATOM   3622 N  N   . VAL A 1 460 ? 142.839 122.139 147.439 1.00 85.73  ? 460 VAL A N   1 
ATOM   3623 C  CA  . VAL A 1 460 ? 144.170 122.340 146.882 1.00 81.61  ? 460 VAL A CA  1 
ATOM   3624 C  C   . VAL A 1 460 ? 144.075 122.926 145.485 1.00 82.30  ? 460 VAL A C   1 
ATOM   3625 O  O   . VAL A 1 460 ? 144.815 123.857 145.144 1.00 90.29  ? 460 VAL A O   1 
ATOM   3626 C  CB  . VAL A 1 460 ? 144.955 121.015 146.890 1.00 77.21  ? 460 VAL A CB  1 
ATOM   3627 C  CG1 . VAL A 1 460 ? 146.187 121.120 146.006 1.00 77.46  ? 460 VAL A CG1 1 
ATOM   3628 C  CG2 . VAL A 1 460 ? 145.343 120.640 148.307 1.00 89.16  ? 460 VAL A CG2 1 
ATOM   3629 N  N   . GLY A 1 461 ? 143.173 122.401 144.656 1.00 79.28  ? 461 GLY A N   1 
ATOM   3630 C  CA  . GLY A 1 461 ? 143.019 122.950 143.318 1.00 80.33  ? 461 GLY A CA  1 
ATOM   3631 C  C   . GLY A 1 461 ? 142.661 124.424 143.341 1.00 79.76  ? 461 GLY A C   1 
ATOM   3632 O  O   . GLY A 1 461 ? 143.284 125.238 142.649 1.00 86.87  ? 461 GLY A O   1 
ATOM   3633 N  N   . VAL A 1 462 ? 141.632 124.869 144.032 1.00 82.48  ? 462 VAL A N   1 
ATOM   3634 C  CA  . VAL A 1 462 ? 141.291 126.324 144.146 1.00 83.61  ? 462 VAL A CA  1 
ATOM   3635 C  C   . VAL A 1 462 ? 142.451 127.125 144.742 1.00 81.33  ? 462 VAL A C   1 
ATOM   3636 O  O   . VAL A 1 462 ? 142.698 128.211 144.265 1.00 80.08  ? 462 VAL A O   1 
ATOM   3637 C  CB  . VAL A 1 462 ? 139.998 126.591 144.944 1.00 88.38  ? 462 VAL A CB  1 
ATOM   3638 C  CG1 . VAL A 1 462 ? 139.893 128.031 145.413 1.00 71.48  ? 462 VAL A CG1 1 
ATOM   3639 C  CG2 . VAL A 1 462 ? 138.747 126.173 144.207 1.00 95.45  ? 462 VAL A CG2 1 
ATOM   3640 N  N   . GLY A 1 463 ? 143.135 126.631 145.764 1.00 87.29  ? 463 GLY A N   1 
ATOM   3641 C  CA  . GLY A 1 463 ? 144.169 127.466 146.340 1.00 80.51  ? 463 GLY A CA  1 
ATOM   3642 C  C   . GLY A 1 463 ? 145.474 127.474 145.576 1.00 80.60  ? 463 GLY A C   1 
ATOM   3643 O  O   . GLY A 1 463 ? 146.360 128.281 145.872 1.00 84.62  ? 463 GLY A O   1 
ATOM   3644 N  N   . VAL A 1 464 ? 145.614 126.590 144.589 1.00 80.52  ? 464 VAL A N   1 
ATOM   3645 C  CA  . VAL A 1 464 ? 146.874 126.437 143.871 1.00 78.76  ? 464 VAL A CA  1 
ATOM   3646 C  C   . VAL A 1 464 ? 146.804 126.932 142.436 1.00 81.52  ? 464 VAL A C   1 
ATOM   3647 O  O   . VAL A 1 464 ? 147.769 127.555 141.968 1.00 84.45  ? 464 VAL A O   1 
ATOM   3648 C  CB  . VAL A 1 464 ? 147.360 124.976 143.921 1.00 84.02  ? 464 VAL A CB  1 
ATOM   3649 C  CG1 . VAL A 1 464 ? 148.169 124.614 142.683 1.00 85.61  ? 464 VAL A CG1 1 
ATOM   3650 C  CG2 . VAL A 1 464 ? 148.178 124.734 145.177 1.00 83.65  ? 464 VAL A CG2 1 
ATOM   3651 N  N   . PHE A 1 465 ? 145.694 126.723 141.728 1.00 90.08  ? 465 PHE A N   1 
ATOM   3652 C  CA  . PHE A 1 465 ? 145.710 126.854 140.272 1.00 86.74  ? 465 PHE A CA  1 
ATOM   3653 C  C   . PHE A 1 465 ? 145.495 128.286 139.798 1.00 88.47  ? 465 PHE A C   1 
ATOM   3654 O  O   . PHE A 1 465 ? 145.040 128.513 138.674 1.00 90.09  ? 465 PHE A O   1 
ATOM   3655 C  CB  . PHE A 1 465 ? 144.688 125.916 139.644 1.00 84.50  ? 465 PHE A CB  1 
ATOM   3656 C  CG  . PHE A 1 465 ? 145.272 124.600 139.224 1.00 89.91  ? 465 PHE A CG  1 
ATOM   3657 C  CD1 . PHE A 1 465 ? 145.649 123.666 140.171 1.00 92.79  ? 465 PHE A CD1 1 
ATOM   3658 C  CD2 . PHE A 1 465 ? 145.476 124.311 137.887 1.00 90.09  ? 465 PHE A CD2 1 
ATOM   3659 C  CE1 . PHE A 1 465 ? 146.197 122.459 139.793 1.00 90.91  ? 465 PHE A CE1 1 
ATOM   3660 C  CE2 . PHE A 1 465 ? 146.023 123.106 137.503 1.00 95.32  ? 465 PHE A CE2 1 
ATOM   3661 C  CZ  . PHE A 1 465 ? 146.386 122.177 138.456 1.00 96.25  ? 465 PHE A CZ  1 
ATOM   3662 N  N   . TYR A 1 466 ? 145.818 129.271 140.631 1.00 85.58  ? 466 TYR A N   1 
ATOM   3663 C  CA  . TYR A 1 466 ? 145.986 130.646 140.183 1.00 81.68  ? 466 TYR A CA  1 
ATOM   3664 C  C   . TYR A 1 466 ? 147.424 130.939 139.778 1.00 84.74  ? 466 TYR A C   1 
ATOM   3665 O  O   . TYR A 1 466 ? 147.690 131.989 139.188 1.00 86.33  ? 466 TYR A O   1 
ATOM   3666 C  CB  . TYR A 1 466 ? 145.538 131.619 141.282 1.00 77.18  ? 466 TYR A CB  1 
ATOM   3667 C  CG  . TYR A 1 466 ? 145.490 133.071 140.863 1.00 84.78  ? 466 TYR A CG  1 
ATOM   3668 C  CD1 . TYR A 1 466 ? 144.461 133.550 140.065 1.00 88.13  ? 466 TYR A CD1 1 
ATOM   3669 C  CD2 . TYR A 1 466 ? 146.466 133.967 141.278 1.00 88.20  ? 466 TYR A CD2 1 
ATOM   3670 C  CE1 . TYR A 1 466 ? 144.410 134.874 139.684 1.00 92.02  ? 466 TYR A CE1 1 
ATOM   3671 C  CE2 . TYR A 1 466 ? 146.422 135.294 140.901 1.00 83.62  ? 466 TYR A CE2 1 
ATOM   3672 C  CZ  . TYR A 1 466 ? 145.392 135.742 140.104 1.00 87.26  ? 466 TYR A CZ  1 
ATOM   3673 O  OH  . TYR A 1 466 ? 145.343 137.062 139.725 1.00 84.41  ? 466 TYR A OH  1 
ATOM   3674 N  N   . ALA A 1 467 ? 148.351 130.025 140.066 1.00 83.45  ? 467 ALA A N   1 
ATOM   3675 C  CA  . ALA A 1 467 ? 149.755 130.233 139.726 1.00 79.59  ? 467 ALA A CA  1 
ATOM   3676 C  C   . ALA A 1 467 ? 150.037 130.393 138.235 1.00 83.87  ? 467 ALA A C   1 
ATOM   3677 O  O   . ALA A 1 467 ? 150.868 131.251 137.890 1.00 91.01  ? 467 ALA A O   1 
ATOM   3678 C  CB  . ALA A 1 467 ? 150.595 129.088 140.309 1.00 80.61  ? 467 ALA A CB  1 
ATOM   3679 N  N   . PRO A 1 468 ? 149.435 129.623 137.318 1.00 71.90  ? 468 PRO A N   1 
ATOM   3680 C  CA  . PRO A 1 468 ? 149.810 129.749 135.896 1.00 76.94  ? 468 PRO A CA  1 
ATOM   3681 C  C   . PRO A 1 468 ? 149.666 131.150 135.320 1.00 82.89  ? 468 PRO A C   1 
ATOM   3682 O  O   . PRO A 1 468 ? 150.161 131.390 134.213 1.00 91.52  ? 468 PRO A O   1 
ATOM   3683 C  CB  . PRO A 1 468 ? 148.863 128.766 135.197 1.00 81.89  ? 468 PRO A CB  1 
ATOM   3684 C  CG  . PRO A 1 468 ? 148.590 127.747 136.223 1.00 74.95  ? 468 PRO A CG  1 
ATOM   3685 C  CD  . PRO A 1 468 ? 148.511 128.491 137.516 1.00 72.23  ? 468 PRO A CD  1 
ATOM   3686 N  N   . GLY A 1 469 ? 149.025 132.077 136.023 1.00 79.18  ? 469 GLY A N   1 
ATOM   3687 C  CA  . GLY A 1 469 ? 148.964 133.447 135.566 1.00 75.58  ? 469 GLY A CA  1 
ATOM   3688 C  C   . GLY A 1 469 ? 150.235 134.238 135.761 1.00 74.50  ? 469 GLY A C   1 
ATOM   3689 O  O   . GLY A 1 469 ? 150.325 135.378 135.299 1.00 83.71  ? 469 GLY A O   1 
ATOM   3690 N  N   . LEU A 1 470 ? 151.224 133.665 136.444 1.00 70.49  ? 470 LEU A N   1 
ATOM   3691 C  CA  . LEU A 1 470 ? 152.516 134.308 136.649 1.00 73.43  ? 470 LEU A CA  1 
ATOM   3692 C  C   . LEU A 1 470 ? 153.606 133.727 135.759 1.00 77.91  ? 470 LEU A C   1 
ATOM   3693 O  O   . LEU A 1 470 ? 154.782 134.058 135.941 1.00 75.50  ? 470 LEU A O   1 
ATOM   3694 C  CB  . LEU A 1 470 ? 152.937 134.198 138.117 1.00 64.06  ? 470 LEU A CB  1 
ATOM   3695 C  CG  . LEU A 1 470 ? 151.881 134.508 139.177 1.00 69.67  ? 470 LEU A CG  1 
ATOM   3696 C  CD1 . LEU A 1 470 ? 152.336 134.007 140.535 1.00 75.30  ? 470 LEU A CD1 1 
ATOM   3697 C  CD2 . LEU A 1 470 ? 151.599 135.997 139.231 1.00 77.96  ? 470 LEU A CD2 1 
ATOM   3698 N  N   . PHE A 1 471 ? 153.253 132.869 134.803 1.00 76.23  ? 471 PHE A N   1 
ATOM   3699 C  CA  . PHE A 1 471 ? 154.240 132.179 133.982 1.00 74.85  ? 471 PHE A CA  1 
ATOM   3700 C  C   . PHE A 1 471 ? 154.632 132.958 132.733 1.00 72.97  ? 471 PHE A C   1 
ATOM   3701 O  O   . PHE A 1 471 ? 155.479 132.487 131.972 1.00 82.72  ? 471 PHE A O   1 
ATOM   3702 C  CB  . PHE A 1 471 ? 153.723 130.793 133.582 1.00 69.93  ? 471 PHE A CB  1 
ATOM   3703 C  CG  . PHE A 1 471 ? 153.604 129.832 134.732 1.00 70.05  ? 471 PHE A CG  1 
ATOM   3704 C  CD1 . PHE A 1 471 ? 154.131 130.142 135.975 1.00 76.32  ? 471 PHE A CD1 1 
ATOM   3705 C  CD2 . PHE A 1 471 ? 152.968 128.615 134.567 1.00 73.10  ? 471 PHE A CD2 1 
ATOM   3706 C  CE1 . PHE A 1 471 ? 154.019 129.260 137.030 1.00 79.50  ? 471 PHE A CE1 1 
ATOM   3707 C  CE2 . PHE A 1 471 ? 152.856 127.729 135.619 1.00 78.00  ? 471 PHE A CE2 1 
ATOM   3708 C  CZ  . PHE A 1 471 ? 153.382 128.052 136.851 1.00 77.91  ? 471 PHE A CZ  1 
ATOM   3709 N  N   . TYR A 1 472 ? 154.043 134.127 132.504 1.00 72.93  ? 472 TYR A N   1 
ATOM   3710 C  CA  . TYR A 1 472 ? 154.421 134.992 131.398 1.00 73.58  ? 472 TYR A CA  1 
ATOM   3711 C  C   . TYR A 1 472 ? 154.920 136.323 131.945 1.00 77.05  ? 472 TYR A C   1 
ATOM   3712 O  O   . TYR A 1 472 ? 154.589 136.715 133.066 1.00 79.53  ? 472 TYR A O   1 
ATOM   3713 C  CB  . TYR A 1 472 ? 153.248 135.230 130.436 1.00 73.34  ? 472 TYR A CB  1 
ATOM   3714 C  CG  . TYR A 1 472 ? 152.087 135.975 131.051 1.00 75.48  ? 472 TYR A CG  1 
ATOM   3715 C  CD1 . TYR A 1 472 ? 152.036 137.363 131.029 1.00 72.41  ? 472 TYR A CD1 1 
ATOM   3716 C  CD2 . TYR A 1 472 ? 151.042 135.291 131.653 1.00 81.37  ? 472 TYR A CD2 1 
ATOM   3717 C  CE1 . TYR A 1 472 ? 150.984 138.046 131.593 1.00 77.65  ? 472 TYR A CE1 1 
ATOM   3718 C  CE2 . TYR A 1 472 ? 149.982 135.967 132.216 1.00 79.56  ? 472 TYR A CE2 1 
ATOM   3719 C  CZ  . TYR A 1 472 ? 149.959 137.344 132.185 1.00 83.40  ? 472 TYR A CZ  1 
ATOM   3720 O  OH  . TYR A 1 472 ? 148.904 138.023 132.748 1.00 91.28  ? 472 TYR A OH  1 
ATOM   3721 N  N   . GLY A 1 473 ? 155.723 137.013 131.137 1.00 83.35  ? 473 GLY A N   1 
ATOM   3722 C  CA  . GLY A 1 473 ? 156.258 138.305 131.491 1.00 81.32  ? 473 GLY A CA  1 
ATOM   3723 C  C   . GLY A 1 473 ? 155.726 139.422 130.613 1.00 80.35  ? 473 GLY A C   1 
ATOM   3724 O  O   . GLY A 1 473 ? 154.824 139.241 129.793 1.00 87.60  ? 473 GLY A O   1 
ATOM   3725 N  N   . GLU A 1 474 ? 156.311 140.606 130.806 1.00 87.24  ? 474 GLU A N   1 
ATOM   3726 C  CA  . GLU A 1 474 ? 155.916 141.772 130.022 1.00 85.61  ? 474 GLU A CA  1 
ATOM   3727 C  C   . GLU A 1 474 ? 156.248 141.590 128.546 1.00 86.74  ? 474 GLU A C   1 
ATOM   3728 O  O   . GLU A 1 474 ? 155.450 141.957 127.676 1.00 83.40  ? 474 GLU A O   1 
ATOM   3729 C  CB  . GLU A 1 474 ? 156.599 143.021 130.572 1.00 90.40  ? 474 GLU A CB  1 
ATOM   3730 C  CG  . GLU A 1 474 ? 156.328 144.282 129.779 1.00 92.69  ? 474 GLU A CG  1 
ATOM   3731 C  CD  . GLU A 1 474 ? 157.043 145.485 130.350 1.00 100.30 ? 474 GLU A CD  1 
ATOM   3732 O  OE1 . GLU A 1 474 ? 157.865 145.304 131.274 1.00 98.94  ? 474 GLU A OE1 1 
ATOM   3733 O  OE2 . GLU A 1 474 ? 156.790 146.610 129.878 1.00 102.51 ? 474 GLU A OE2 1 
ATOM   3734 N  N   . LYS A 1 475 ? 157.416 141.026 128.243 1.00 91.93  ? 475 LYS A N   1 
ATOM   3735 C  CA  . LYS A 1 475 ? 157.887 140.875 126.873 1.00 93.49  ? 475 LYS A CA  1 
ATOM   3736 C  C   . LYS A 1 475 ? 157.677 139.468 126.329 1.00 92.59  ? 475 LYS A C   1 
ATOM   3737 O  O   . LYS A 1 475 ? 158.236 139.125 125.283 1.00 91.97  ? 475 LYS A O   1 
ATOM   3738 C  CB  . LYS A 1 475 ? 159.363 141.263 126.779 1.00 90.04  ? 475 LYS A CB  1 
ATOM   3739 C  CG  . LYS A 1 475 ? 159.679 142.629 127.357 1.00 85.42  ? 475 LYS A CG  1 
ATOM   3740 C  CD  . LYS A 1 475 ? 159.141 143.740 126.474 1.00 86.28  ? 475 LYS A CD  1 
ATOM   3741 C  CE  . LYS A 1 475 ? 159.876 145.045 126.723 1.00 88.23  ? 475 LYS A CE  1 
ATOM   3742 N  NZ  . LYS A 1 475 ? 159.484 146.105 125.757 1.00 94.31  ? 475 LYS A NZ  1 
ATOM   3743 N  N   . SER A 1 476 ? 156.932 138.647 127.055 1.00 80.56  ? 476 SER A N   1 
ATOM   3744 C  CA  . SER A 1 476 ? 156.532 137.294 126.591 1.00 76.36  ? 476 SER A CA  1 
ATOM   3745 C  C   . SER A 1 476 ? 155.740 137.402 125.282 1.00 78.75  ? 476 SER A C   1 
ATOM   3746 O  O   . SER A 1 476 ? 155.081 138.402 125.085 1.00 88.39  ? 476 SER A O   1 
ATOM   3747 C  CB  . SER A 1 476 ? 155.780 136.448 127.657 1.00 79.30  ? 476 SER A CB  1 
ATOM   3748 O  OG  . SER A 1 476 ? 156.632 136.017 128.694 1.00 84.44  ? 476 SER A OG  1 
ATOM   3749 N  N   . PRO A 1 477 ? 155.841 136.440 124.349 1.00 73.50  ? 477 PRO A N   1 
ATOM   3750 C  CA  . PRO A 1 477 ? 155.004 136.451 123.146 1.00 72.04  ? 477 PRO A CA  1 
ATOM   3751 C  C   . PRO A 1 477 ? 153.522 136.352 123.482 1.00 75.38  ? 477 PRO A C   1 
ATOM   3752 O  O   . PRO A 1 477 ? 153.112 135.793 124.503 1.00 82.47  ? 477 PRO A O   1 
ATOM   3753 C  CB  . PRO A 1 477 ? 155.484 135.226 122.356 1.00 75.59  ? 477 PRO A CB  1 
ATOM   3754 C  CG  . PRO A 1 477 ? 156.316 134.434 123.305 1.00 77.65  ? 477 PRO A CG  1 
ATOM   3755 C  CD  . PRO A 1 477 ? 156.880 135.402 124.285 1.00 75.52  ? 477 PRO A CD  1 
ATOM   3756 N  N   . ILE A 1 478 ? 152.691 137.052 122.732 1.00 67.58  ? 478 ILE A N   1 
ATOM   3757 C  CA  . ILE A 1 478 ? 151.202 137.087 122.925 1.00 68.15  ? 478 ILE A CA  1 
ATOM   3758 C  C   . ILE A 1 478 ? 150.523 135.704 123.041 1.00 73.17  ? 478 ILE A C   1 
ATOM   3759 O  O   . ILE A 1 478 ? 149.703 135.550 123.920 1.00 77.25  ? 478 ILE A O   1 
ATOM   3760 C  CB  . ILE A 1 478 ? 150.534 137.977 121.839 1.00 74.89  ? 478 ILE A CB  1 
ATOM   3761 C  CG1 . ILE A 1 478 ? 150.996 139.435 121.931 1.00 74.09  ? 478 ILE A CG1 1 
ATOM   3762 C  CG2 . ILE A 1 478 ? 149.018 137.862 121.870 1.00 76.05  ? 478 ILE A CG2 1 
ATOM   3763 C  CD1 . ILE A 1 478 ? 150.550 140.164 123.168 1.00 74.43  ? 478 ILE A CD1 1 
ATOM   3764 N  N   . ALA A 1 479 ? 150.851 134.782 122.161 1.00 69.49  ? 479 ALA A N   1 
ATOM   3765 C  CA  . ALA A 1 479 ? 150.334 133.418 122.208 1.00 69.26  ? 479 ALA A CA  1 
ATOM   3766 C  C   . ALA A 1 479 ? 150.753 132.674 123.490 1.00 78.02  ? 479 ALA A C   1 
ATOM   3767 O  O   . ALA A 1 479 ? 149.934 131.947 123.975 1.00 83.70  ? 479 ALA A O   1 
ATOM   3768 C  CB  . ALA A 1 479 ? 150.705 132.749 120.914 1.00 65.94  ? 479 ALA A CB  1 
ATOM   3769 N  N   . VAL A 1 480 ? 151.990 132.799 123.951 1.00 72.18  ? 480 VAL A N   1 
ATOM   3770 C  CA  . VAL A 1 480 ? 152.342 132.206 125.239 1.00 68.00  ? 480 VAL A CA  1 
ATOM   3771 C  C   . VAL A 1 480 ? 151.543 132.857 126.358 1.00 71.24  ? 480 VAL A C   1 
ATOM   3772 O  O   . VAL A 1 480 ? 151.026 132.178 127.260 1.00 77.89  ? 480 VAL A O   1 
ATOM   3773 C  CB  . VAL A 1 480 ? 153.859 132.332 125.480 1.00 66.58  ? 480 VAL A CB  1 
ATOM   3774 C  CG1 . VAL A 1 480 ? 154.200 132.028 126.928 1.00 72.12  ? 480 VAL A CG1 1 
ATOM   3775 C  CG2 . VAL A 1 480 ? 154.622 131.416 124.539 1.00 74.96  ? 480 VAL A CG2 1 
ATOM   3776 N  N   . MET A 1 481 ? 151.431 134.186 126.315 1.00 81.14  ? 481 MET A N   1 
ATOM   3777 C  CA  . MET A 1 481 ? 150.663 134.900 127.326 1.00 73.09  ? 481 MET A CA  1 
ATOM   3778 C  C   . MET A 1 481 ? 149.211 134.446 127.316 1.00 75.02  ? 481 MET A C   1 
ATOM   3779 O  O   . MET A 1 481 ? 148.618 134.216 128.372 1.00 82.83  ? 481 MET A O   1 
ATOM   3780 C  CB  . MET A 1 481 ? 150.807 136.411 127.097 1.00 76.52  ? 481 MET A CB  1 
ATOM   3781 C  CG  . MET A 1 481 ? 149.916 137.387 127.895 1.00 81.43  ? 481 MET A CG  1 
ATOM   3782 S  SD  . MET A 1 481 ? 148.115 137.241 127.900 1.00 100.80 ? 481 MET A SD  1 
ATOM   3783 C  CE  . MET A 1 481 ? 147.732 137.943 126.302 1.00 86.36  ? 481 MET A CE  1 
ATOM   3784 N  N   . GLU A 1 482 ? 148.622 134.299 126.125 1.00 71.15  ? 482 GLU A N   1 
ATOM   3785 C  CA  . GLU A 1 482 ? 147.232 133.859 126.031 1.00 66.77  ? 482 GLU A CA  1 
ATOM   3786 C  C   . GLU A 1 482 ? 147.058 132.447 126.569 1.00 72.71  ? 482 GLU A C   1 
ATOM   3787 O  O   . GLU A 1 482 ? 146.082 132.158 127.269 1.00 89.50  ? 482 GLU A O   1 
ATOM   3788 C  CB  . GLU A 1 482 ? 146.744 133.936 124.585 1.00 61.50  ? 482 GLU A CB  1 
ATOM   3789 C  CG  . GLU A 1 482 ? 146.649 135.337 124.023 1.00 77.25  ? 482 GLU A CG  1 
ATOM   3790 C  CD  . GLU A 1 482 ? 145.238 135.877 124.051 1.00 85.89  ? 482 GLU A CD  1 
ATOM   3791 O  OE1 . GLU A 1 482 ? 144.385 135.277 124.736 1.00 89.45  ? 482 GLU A OE1 1 
ATOM   3792 O  OE2 . GLU A 1 482 ? 144.978 136.898 123.383 1.00 85.72  ? 482 GLU A OE2 1 
ATOM   3793 N  N   . TYR A 1 483 ? 147.989 131.551 126.241 1.00 52.86  ? 483 TYR A N   1 
ATOM   3794 C  CA  . TYR A 1 483 ? 147.920 130.185 126.749 1.00 60.51  ? 483 TYR A CA  1 
ATOM   3795 C  C   . TYR A 1 483 ? 147.908 130.174 128.275 1.00 64.04  ? 483 TYR A C   1 
ATOM   3796 O  O   . TYR A 1 483 ? 147.017 129.582 128.905 1.00 64.05  ? 483 TYR A O   1 
ATOM   3797 C  CB  . TYR A 1 483 ? 149.102 129.384 126.203 1.00 58.02  ? 483 TYR A CB  1 
ATOM   3798 C  CG  . TYR A 1 483 ? 149.273 128.007 126.796 1.00 61.77  ? 483 TYR A CG  1 
ATOM   3799 C  CD1 . TYR A 1 483 ? 148.481 126.948 126.383 1.00 61.99  ? 483 TYR A CD1 1 
ATOM   3800 C  CD2 . TYR A 1 483 ? 150.237 127.766 127.766 1.00 67.82  ? 483 TYR A CD2 1 
ATOM   3801 C  CE1 . TYR A 1 483 ? 148.639 125.689 126.920 1.00 55.23  ? 483 TYR A CE1 1 
ATOM   3802 C  CE2 . TYR A 1 483 ? 150.402 126.513 128.309 1.00 62.96  ? 483 TYR A CE2 1 
ATOM   3803 C  CZ  . TYR A 1 483 ? 149.601 125.478 127.884 1.00 56.21  ? 483 TYR A CZ  1 
ATOM   3804 O  OH  . TYR A 1 483 ? 149.764 124.225 128.423 1.00 71.44  ? 483 TYR A OH  1 
ATOM   3805 N  N   . TRP A 1 484 ? 148.869 130.865 128.888 1.00 67.89  ? 484 TRP A N   1 
ATOM   3806 C  CA  . TRP A 1 484 ? 148.937 130.857 130.347 1.00 53.84  ? 484 TRP A CA  1 
ATOM   3807 C  C   . TRP A 1 484 ? 147.775 131.616 130.978 1.00 59.07  ? 484 TRP A C   1 
ATOM   3808 O  O   . TRP A 1 484 ? 147.349 131.278 132.088 1.00 69.77  ? 484 TRP A O   1 
ATOM   3809 C  CB  . TRP A 1 484 ? 150.274 131.423 130.820 1.00 61.15  ? 484 TRP A CB  1 
ATOM   3810 C  CG  . TRP A 1 484 ? 151.425 130.485 130.596 1.00 65.41  ? 484 TRP A CG  1 
ATOM   3811 C  CD1 . TRP A 1 484 ? 152.578 130.755 129.925 1.00 74.16  ? 484 TRP A CD1 1 
ATOM   3812 C  CD2 . TRP A 1 484 ? 151.528 129.125 131.040 1.00 62.25  ? 484 TRP A CD2 1 
ATOM   3813 N  NE1 . TRP A 1 484 ? 153.396 129.654 129.925 1.00 72.80  ? 484 TRP A NE1 1 
ATOM   3814 C  CE2 . TRP A 1 484 ? 152.774 128.638 130.602 1.00 73.26  ? 484 TRP A CE2 1 
ATOM   3815 C  CE3 . TRP A 1 484 ? 150.691 128.273 131.767 1.00 60.00  ? 484 TRP A CE3 1 
ATOM   3816 C  CZ2 . TRP A 1 484 ? 153.203 127.341 130.867 1.00 73.06  ? 484 TRP A CZ2 1 
ATOM   3817 C  CZ3 . TRP A 1 484 ? 151.116 126.985 132.025 1.00 59.68  ? 484 TRP A CZ3 1 
ATOM   3818 C  CH2 . TRP A 1 484 ? 152.361 126.531 131.577 1.00 62.92  ? 484 TRP A CH2 1 
ATOM   3819 N  N   . ARG A 1 485 ? 147.243 132.632 130.295 1.00 60.87  ? 485 ARG A N   1 
ATOM   3820 C  CA  . ARG A 1 485 ? 146.121 133.385 130.839 1.00 54.87  ? 485 ARG A CA  1 
ATOM   3821 C  C   . ARG A 1 485 ? 144.844 132.554 130.829 1.00 60.10  ? 485 ARG A C   1 
ATOM   3822 O  O   . ARG A 1 485 ? 144.086 132.561 131.804 1.00 74.14  ? 485 ARG A O   1 
ATOM   3823 C  CB  . ARG A 1 485 ? 145.928 134.681 130.052 1.00 51.74  ? 485 ARG A CB  1 
ATOM   3824 C  CG  . ARG A 1 485 ? 144.638 135.418 130.363 1.00 49.40  ? 485 ARG A CG  1 
ATOM   3825 C  CD  . ARG A 1 485 ? 144.632 136.810 129.760 1.00 59.38  ? 485 ARG A CD  1 
ATOM   3826 N  NE  . ARG A 1 485 ? 144.342 136.787 128.332 1.00 63.46  ? 485 ARG A NE  1 
ATOM   3827 C  CZ  . ARG A 1 485 ? 143.171 137.111 127.800 1.00 67.14  ? 485 ARG A CZ  1 
ATOM   3828 N  NH1 . ARG A 1 485 ? 142.158 137.506 128.552 1.00 72.04  ? 485 ARG A NH1 1 
ATOM   3829 N  NH2 . ARG A 1 485 ? 143.013 137.036 126.483 1.00 66.80  ? 485 ARG A NH2 1 
ATOM   3830 N  N   . TRP A 1 486 ? 144.622 131.757 129.812 1.00 64.51  ? 486 TRP A N   1 
ATOM   3831 C  CA  . TRP A 1 486 ? 143.393 130.940 129.778 1.00 59.78  ? 486 TRP A CA  1 
ATOM   3832 C  C   . TRP A 1 486 ? 143.585 129.736 130.683 1.00 68.08  ? 486 TRP A C   1 
ATOM   3833 O  O   . TRP A 1 486 ? 142.604 129.202 131.151 1.00 68.63  ? 486 TRP A O   1 
ATOM   3834 C  CB  . TRP A 1 486 ? 143.014 130.581 128.343 1.00 60.41  ? 486 TRP A CB  1 
ATOM   3835 C  CG  . TRP A 1 486 ? 142.577 131.790 127.587 1.00 71.48  ? 486 TRP A CG  1 
ATOM   3836 C  CD1 . TRP A 1 486 ? 143.201 132.385 126.535 1.00 76.37  ? 486 TRP A CD1 1 
ATOM   3837 C  CD2 . TRP A 1 486 ? 141.419 132.583 127.870 1.00 73.09  ? 486 TRP A CD2 1 
ATOM   3838 N  NE1 . TRP A 1 486 ? 142.507 133.492 126.141 1.00 70.73  ? 486 TRP A NE1 1 
ATOM   3839 C  CE2 . TRP A 1 486 ? 141.408 133.635 126.936 1.00 72.79  ? 486 TRP A CE2 1 
ATOM   3840 C  CE3 . TRP A 1 486 ? 140.389 132.493 128.807 1.00 69.59  ? 486 TRP A CE3 1 
ATOM   3841 C  CZ2 . TRP A 1 486 ? 140.404 134.596 126.919 1.00 74.25  ? 486 TRP A CZ2 1 
ATOM   3842 C  CZ3 . TRP A 1 486 ? 139.399 133.445 128.789 1.00 70.67  ? 486 TRP A CZ3 1 
ATOM   3843 C  CH2 . TRP A 1 486 ? 139.418 134.483 127.864 1.00 77.27  ? 486 TRP A CH2 1 
ATOM   3844 N  N   . TRP A 1 487 ? 144.829 129.397 130.974 1.00 75.75  ? 487 TRP A N   1 
ATOM   3845 C  CA  . TRP A 1 487 ? 144.988 128.449 132.071 1.00 64.01  ? 487 TRP A CA  1 
ATOM   3846 C  C   . TRP A 1 487 ? 144.331 128.933 133.359 1.00 62.07  ? 487 TRP A C   1 
ATOM   3847 O  O   . TRP A 1 487 ? 144.053 128.116 134.242 1.00 69.66  ? 487 TRP A O   1 
ATOM   3848 C  CB  . TRP A 1 487 ? 146.467 128.179 132.342 1.00 67.32  ? 487 TRP A CB  1 
ATOM   3849 C  CG  . TRP A 1 487 ? 146.991 126.925 131.727 1.00 73.18  ? 487 TRP A CG  1 
ATOM   3850 C  CD1 . TRP A 1 487 ? 147.095 126.647 130.400 1.00 81.76  ? 487 TRP A CD1 1 
ATOM   3851 C  CD2 . TRP A 1 487 ? 147.489 125.774 132.420 1.00 70.41  ? 487 TRP A CD2 1 
ATOM   3852 N  NE1 . TRP A 1 487 ? 147.629 125.397 130.220 1.00 77.88  ? 487 TRP A NE1 1 
ATOM   3853 C  CE2 . TRP A 1 487 ? 147.881 124.840 131.445 1.00 77.12  ? 487 TRP A CE2 1 
ATOM   3854 C  CE3 . TRP A 1 487 ? 147.641 125.446 133.768 1.00 69.89  ? 487 TRP A CE3 1 
ATOM   3855 C  CZ2 . TRP A 1 487 ? 148.416 123.599 131.775 1.00 78.43  ? 487 TRP A CZ2 1 
ATOM   3856 C  CZ3 . TRP A 1 487 ? 148.173 124.214 134.094 1.00 73.90  ? 487 TRP A CZ3 1 
ATOM   3857 C  CH2 . TRP A 1 487 ? 148.552 123.305 133.103 1.00 78.27  ? 487 TRP A CH2 1 
ATOM   3858 N  N   . VAL A 1 488 ? 144.092 130.222 133.572 1.00 63.12  ? 488 VAL A N   1 
ATOM   3859 C  CA  . VAL A 1 488 ? 143.493 130.841 134.781 1.00 62.84  ? 488 VAL A CA  1 
ATOM   3860 C  C   . VAL A 1 488 ? 142.026 131.273 134.577 1.00 63.97  ? 488 VAL A C   1 
ATOM   3861 O  O   . VAL A 1 488 ? 141.247 131.012 135.460 1.00 69.64  ? 488 VAL A O   1 
ATOM   3862 C  CB  . VAL A 1 488 ? 144.385 132.009 135.293 1.00 60.98  ? 488 VAL A CB  1 
ATOM   3863 C  CG1 . VAL A 1 488 ? 143.672 132.913 136.283 1.00 53.50  ? 488 VAL A CG1 1 
ATOM   3864 C  CG2 . VAL A 1 488 ? 145.705 131.512 135.855 1.00 67.66  ? 488 VAL A CG2 1 
ATOM   3865 N  N   . VAL A 1 489 ? 141.660 131.944 133.487 1.00 74.70  ? 489 VAL A N   1 
ATOM   3866 C  CA  . VAL A 1 489 ? 140.288 132.498 133.268 1.00 71.17  ? 489 VAL A CA  1 
ATOM   3867 C  C   . VAL A 1 489 ? 139.335 131.355 132.913 1.00 74.16  ? 489 VAL A C   1 
ATOM   3868 O  O   . VAL A 1 489 ? 138.171 131.451 133.229 1.00 75.33  ? 489 VAL A O   1 
ATOM   3869 C  CB  . VAL A 1 489 ? 140.262 133.655 132.242 1.00 75.12  ? 489 VAL A CB  1 
ATOM   3870 C  CG1 . VAL A 1 489 ? 138.894 134.310 132.117 1.00 76.58  ? 489 VAL A CG1 1 
ATOM   3871 C  CG2 . VAL A 1 489 ? 141.331 134.690 132.523 1.00 77.97  ? 489 VAL A CG2 1 
ATOM   3872 N  N   . HIS A 1 490 ? 139.884 130.284 132.363 1.00 76.58  ? 490 HIS A N   1 
ATOM   3873 C  CA  . HIS A 1 490 ? 139.026 129.154 132.034 1.00 69.02  ? 490 HIS A CA  1 
ATOM   3874 C  C   . HIS A 1 490 ? 139.223 127.972 132.973 1.00 69.97  ? 490 HIS A C   1 
ATOM   3875 O  O   . HIS A 1 490 ? 138.252 127.462 133.533 1.00 74.70  ? 490 HIS A O   1 
ATOM   3876 C  CB  . HIS A 1 490 ? 139.266 128.721 130.580 1.00 74.15  ? 490 HIS A CB  1 
ATOM   3877 C  CG  . HIS A 1 490 ? 138.585 127.442 130.203 1.00 73.72  ? 490 HIS A CG  1 
ATOM   3878 N  ND1 . HIS A 1 490 ? 137.402 127.413 129.497 1.00 73.99  ? 490 HIS A ND1 1 
ATOM   3879 C  CD2 . HIS A 1 490 ? 138.931 126.150 130.408 1.00 67.44  ? 490 HIS A CD2 1 
ATOM   3880 C  CE1 . HIS A 1 490 ? 137.040 126.159 129.299 1.00 73.39  ? 490 HIS A CE1 1 
ATOM   3881 N  NE2 . HIS A 1 490 ? 137.950 125.371 129.843 1.00 78.20  ? 490 HIS A NE2 1 
ATOM   3882 N  N   . LEU A 1 491 ? 140.462 127.521 133.166 1.00 74.53  ? 491 LEU A N   1 
ATOM   3883 C  CA  . LEU A 1 491 ? 140.683 126.318 133.962 1.00 68.40  ? 491 LEU A CA  1 
ATOM   3884 C  C   . LEU A 1 491 ? 140.473 126.563 135.451 1.00 68.57  ? 491 LEU A C   1 
ATOM   3885 O  O   . LEU A 1 491 ? 140.036 125.657 136.167 1.00 83.97  ? 491 LEU A O   1 
ATOM   3886 C  CB  . LEU A 1 491 ? 142.085 125.770 133.709 1.00 67.42  ? 491 LEU A CB  1 
ATOM   3887 C  CG  . LEU A 1 491 ? 142.325 124.310 134.090 1.00 64.99  ? 491 LEU A CG  1 
ATOM   3888 C  CD1 . LEU A 1 491 ? 141.138 123.451 133.694 1.00 69.18  ? 491 LEU A CD1 1 
ATOM   3889 C  CD2 . LEU A 1 491 ? 143.600 123.795 133.450 1.00 78.82  ? 491 LEU A CD2 1 
ATOM   3890 N  N   . TRP A 1 492 ? 140.783 127.762 135.943 1.00 73.58  ? 492 TRP A N   1 
ATOM   3891 C  CA  . TRP A 1 492 ? 140.676 128.035 137.372 1.00 77.19  ? 492 TRP A CA  1 
ATOM   3892 C  C   . TRP A 1 492 ? 139.312 128.569 137.779 1.00 78.27  ? 492 TRP A C   1 
ATOM   3893 O  O   . TRP A 1 492 ? 138.896 128.365 138.927 1.00 81.90  ? 492 TRP A O   1 
ATOM   3894 C  CB  . TRP A 1 492 ? 141.757 129.028 137.805 1.00 79.01  ? 492 TRP A CB  1 
ATOM   3895 C  CG  . TRP A 1 492 ? 141.797 129.285 139.279 1.00 78.97  ? 492 TRP A CG  1 
ATOM   3896 C  CD1 . TRP A 1 492 ? 142.078 128.385 140.259 1.00 79.32  ? 492 TRP A CD1 1 
ATOM   3897 C  CD2 . TRP A 1 492 ? 141.547 130.531 139.939 1.00 80.98  ? 492 TRP A CD2 1 
ATOM   3898 N  NE1 . TRP A 1 492 ? 142.024 128.990 141.489 1.00 81.63  ? 492 TRP A NE1 1 
ATOM   3899 C  CE2 . TRP A 1 492 ? 141.699 130.310 141.320 1.00 80.02  ? 492 TRP A CE2 1 
ATOM   3900 C  CE3 . TRP A 1 492 ? 141.214 131.814 139.496 1.00 82.32  ? 492 TRP A CE3 1 
ATOM   3901 C  CZ2 . TRP A 1 492 ? 141.527 131.321 142.262 1.00 76.75  ? 492 TRP A CZ2 1 
ATOM   3902 C  CZ3 . TRP A 1 492 ? 141.043 132.816 140.430 1.00 79.02  ? 492 TRP A CZ3 1 
ATOM   3903 C  CH2 . TRP A 1 492 ? 141.199 132.564 141.799 1.00 73.92  ? 492 TRP A CH2 1 
ATOM   3904 N  N   . VAL A 1 493 ? 138.601 129.243 136.880 1.00 84.79  ? 493 VAL A N   1 
ATOM   3905 C  CA  . VAL A 1 493 ? 137.292 129.794 137.212 1.00 78.74  ? 493 VAL A CA  1 
ATOM   3906 C  C   . VAL A 1 493 ? 136.201 128.838 136.754 1.00 80.94  ? 493 VAL A C   1 
ATOM   3907 O  O   . VAL A 1 493 ? 135.387 128.382 137.565 1.00 79.60  ? 493 VAL A O   1 
ATOM   3908 C  CB  . VAL A 1 493 ? 137.099 131.191 136.595 1.00 85.19  ? 493 VAL A CB  1 
ATOM   3909 C  CG1 . VAL A 1 493 ? 135.764 131.772 137.027 1.00 84.69  ? 493 VAL A CG1 1 
ATOM   3910 C  CG2 . VAL A 1 493 ? 138.233 132.109 137.009 1.00 83.18  ? 493 VAL A CG2 1 
ATOM   3911 N  N   . GLU A 1 494 ? 136.164 128.533 135.455 1.00 96.56  ? 494 GLU A N   1 
ATOM   3912 C  CA  . GLU A 1 494 ? 135.173 127.580 134.964 1.00 93.31  ? 494 GLU A CA  1 
ATOM   3913 C  C   . GLU A 1 494 ? 135.410 126.196 135.552 1.00 93.17  ? 494 GLU A C   1 
ATOM   3914 O  O   . GLU A 1 494 ? 134.468 125.528 135.987 1.00 94.23  ? 494 GLU A O   1 
ATOM   3915 C  CB  . GLU A 1 494 ? 135.196 127.527 133.439 1.00 91.59  ? 494 GLU A CB  1 
ATOM   3916 C  CG  . GLU A 1 494 ? 135.275 128.884 132.771 1.00 92.51  ? 494 GLU A CG  1 
ATOM   3917 C  CD  . GLU A 1 494 ? 135.020 128.804 131.284 1.00 97.21  ? 494 GLU A CD  1 
ATOM   3918 O  OE1 . GLU A 1 494 ? 134.482 127.771 130.832 1.00 97.59  ? 494 GLU A OE1 1 
ATOM   3919 O  OE2 . GLU A 1 494 ? 135.365 129.765 130.567 1.00 98.08  ? 494 GLU A OE2 1 
ATOM   3920 N  N   . GLY A 1 495 ? 136.661 125.754 135.581 1.00 94.60  ? 495 GLY A N   1 
ATOM   3921 C  CA  . GLY A 1 495 ? 137.025 124.530 136.259 1.00 89.17  ? 495 GLY A CA  1 
ATOM   3922 C  C   . GLY A 1 495 ? 137.554 124.828 137.647 1.00 91.30  ? 495 GLY A C   1 
ATOM   3923 O  O   . GLY A 1 495 ? 137.860 125.969 137.978 1.00 96.08  ? 495 GLY A O   1 
ATOM   3924 N  N   . PHE A 1 496 ? 137.620 123.784 138.472 1.00 92.04  ? 496 PHE A N   1 
ATOM   3925 C  CA  . PHE A 1 496 ? 138.153 123.853 139.833 1.00 96.67  ? 496 PHE A CA  1 
ATOM   3926 C  C   . PHE A 1 496 ? 137.279 124.687 140.766 1.00 94.74  ? 496 PHE A C   1 
ATOM   3927 O  O   . PHE A 1 496 ? 137.513 124.710 141.974 1.00 101.14 ? 496 PHE A O   1 
ATOM   3928 C  CB  . PHE A 1 496 ? 139.589 124.392 139.852 1.00 87.86  ? 496 PHE A CB  1 
ATOM   3929 C  CG  . PHE A 1 496 ? 140.622 123.379 139.465 1.00 96.87  ? 496 PHE A CG  1 
ATOM   3930 C  CD1 . PHE A 1 496 ? 140.683 122.156 140.105 1.00 101.67 ? 496 PHE A CD1 1 
ATOM   3931 C  CD2 . PHE A 1 496 ? 141.532 123.650 138.459 1.00 92.97  ? 496 PHE A CD2 1 
ATOM   3932 C  CE1 . PHE A 1 496 ? 141.634 121.222 139.749 1.00 101.39 ? 496 PHE A CE1 1 
ATOM   3933 C  CE2 . PHE A 1 496 ? 142.483 122.720 138.098 1.00 92.97  ? 496 PHE A CE2 1 
ATOM   3934 C  CZ  . PHE A 1 496 ? 142.534 121.505 138.744 1.00 98.18  ? 496 PHE A CZ  1 
ATOM   3935 N  N   . PHE A 1 497 ? 136.255 125.355 140.241 1.00 89.67  ? 497 PHE A N   1 
ATOM   3936 C  CA  . PHE A 1 497 ? 135.325 126.092 141.088 1.00 86.37  ? 497 PHE A CA  1 
ATOM   3937 C  C   . PHE A 1 497 ? 134.020 125.317 141.181 1.00 91.26  ? 497 PHE A C   1 
ATOM   3938 O  O   . PHE A 1 497 ? 133.409 125.250 142.250 1.00 98.18  ? 497 PHE A O   1 
ATOM   3939 C  CB  . PHE A 1 497 ? 135.082 127.501 140.551 1.00 91.88  ? 497 PHE A CB  1 
ATOM   3940 C  CG  . PHE A 1 497 ? 135.965 128.549 141.167 1.00 94.71  ? 497 PHE A CG  1 
ATOM   3941 C  CD1 . PHE A 1 497 ? 137.246 128.236 141.585 1.00 94.75  ? 497 PHE A CD1 1 
ATOM   3942 C  CD2 . PHE A 1 497 ? 135.518 129.849 141.318 1.00 97.41  ? 497 PHE A CD2 1 
ATOM   3943 C  CE1 . PHE A 1 497 ? 138.063 129.200 142.147 1.00 96.44  ? 497 PHE A CE1 1 
ATOM   3944 C  CE2 . PHE A 1 497 ? 136.330 130.817 141.880 1.00 95.86  ? 497 PHE A CE2 1 
ATOM   3945 C  CZ  . PHE A 1 497 ? 137.604 130.490 142.294 1.00 92.97  ? 497 PHE A CZ  1 
ATOM   3946 N  N   . GLU A 1 498 ? 133.592 124.718 140.067 1.00 93.84  ? 498 GLU A N   1 
ATOM   3947 C  CA  . GLU A 1 498 ? 132.479 123.776 140.132 1.00 98.54  ? 498 GLU A CA  1 
ATOM   3948 C  C   . GLU A 1 498 ? 132.839 122.562 140.974 1.00 102.23 ? 498 GLU A C   1 
ATOM   3949 O  O   . GLU A 1 498 ? 131.987 122.022 141.687 1.00 109.60 ? 498 GLU A O   1 
ATOM   3950 C  CB  . GLU A 1 498 ? 132.047 123.346 138.731 1.00 100.79 ? 498 GLU A CB  1 
ATOM   3951 C  CG  . GLU A 1 498 ? 131.986 124.465 137.721 1.00 106.01 ? 498 GLU A CG  1 
ATOM   3952 C  CD  . GLU A 1 498 ? 131.940 123.964 136.294 1.00 111.08 ? 498 GLU A CD  1 
ATOM   3953 O  OE1 . GLU A 1 498 ? 131.983 122.734 136.097 1.00 111.50 ? 498 GLU A OE1 1 
ATOM   3954 O  OE2 . GLU A 1 498 ? 131.839 124.799 135.369 1.00 109.82 ? 498 GLU A OE2 1 
ATOM   3955 N  N   . VAL A 1 499 ? 134.093 122.120 140.906 1.00 81.70  ? 499 VAL A N   1 
ATOM   3956 C  CA  . VAL A 1 499 ? 134.533 121.014 141.751 1.00 78.61  ? 499 VAL A CA  1 
ATOM   3957 C  C   . VAL A 1 499 ? 134.419 121.397 143.221 1.00 82.74  ? 499 VAL A C   1 
ATOM   3958 O  O   . VAL A 1 499 ? 133.924 120.622 144.048 1.00 91.19  ? 499 VAL A O   1 
ATOM   3959 C  CB  . VAL A 1 499 ? 135.968 120.595 141.387 1.00 74.18  ? 499 VAL A CB  1 
ATOM   3960 C  CG1 . VAL A 1 499 ? 136.413 119.425 142.246 1.00 76.00  ? 499 VAL A CG1 1 
ATOM   3961 C  CG2 . VAL A 1 499 ? 136.058 120.241 139.915 1.00 82.72  ? 499 VAL A CG2 1 
ATOM   3962 N  N   . PHE A 1 500 ? 134.868 122.607 143.564 1.00 81.60  ? 500 PHE A N   1 
ATOM   3963 C  CA  . PHE A 1 500 ? 134.773 123.069 144.945 1.00 80.68  ? 500 PHE A CA  1 
ATOM   3964 C  C   . PHE A 1 500 ? 133.325 123.196 145.393 1.00 90.12  ? 500 PHE A C   1 
ATOM   3965 O  O   . PHE A 1 500 ? 132.972 122.784 146.502 1.00 101.07 ? 500 PHE A O   1 
ATOM   3966 C  CB  . PHE A 1 500 ? 135.500 124.402 145.107 1.00 80.86  ? 500 PHE A CB  1 
ATOM   3967 C  CG  . PHE A 1 500 ? 135.569 124.881 146.527 1.00 81.61  ? 500 PHE A CG  1 
ATOM   3968 C  CD1 . PHE A 1 500 ? 136.362 124.229 147.453 1.00 80.09  ? 500 PHE A CD1 1 
ATOM   3969 C  CD2 . PHE A 1 500 ? 134.834 125.979 146.936 1.00 87.81  ? 500 PHE A CD2 1 
ATOM   3970 C  CE1 . PHE A 1 500 ? 136.425 124.662 148.757 1.00 79.13  ? 500 PHE A CE1 1 
ATOM   3971 C  CE2 . PHE A 1 500 ? 134.892 126.418 148.243 1.00 88.53  ? 500 PHE A CE2 1 
ATOM   3972 C  CZ  . PHE A 1 500 ? 135.688 125.758 149.153 1.00 82.06  ? 500 PHE A CZ  1 
ATOM   3973 N  N   . ALA A 1 501 ? 132.473 123.771 144.541 1.00 87.72  ? 501 ALA A N   1 
ATOM   3974 C  CA  . ALA A 1 501 ? 131.067 123.913 144.885 1.00 84.29  ? 501 ALA A CA  1 
ATOM   3975 C  C   . ALA A 1 501 ? 130.411 122.556 145.093 1.00 92.46  ? 501 ALA A C   1 
ATOM   3976 O  O   . ALA A 1 501 ? 129.675 122.360 146.063 1.00 104.06 ? 501 ALA A O   1 
ATOM   3977 C  CB  . ALA A 1 501 ? 130.340 124.704 143.800 1.00 86.04  ? 501 ALA A CB  1 
ATOM   3978 N  N   . THR A 1 502 ? 130.720 121.619 144.226 1.00 86.75  ? 502 THR A N   1 
ATOM   3979 C  CA  . THR A 1 502 ? 130.132 120.268 144.283 1.00 87.05  ? 502 THR A CA  1 
ATOM   3980 C  C   . THR A 1 502 ? 130.591 119.554 145.556 1.00 94.48  ? 502 THR A C   1 
ATOM   3981 O  O   . THR A 1 502 ? 129.751 118.950 146.214 1.00 103.71 ? 502 THR A O   1 
ATOM   3982 C  CB  . THR A 1 502 ? 130.411 119.533 142.960 1.00 89.27  ? 502 THR A CB  1 
ATOM   3983 O  OG1 . THR A 1 502 ? 129.882 120.349 141.920 1.00 94.25  ? 502 THR A OG1 1 
ATOM   3984 C  CG2 . THR A 1 502 ? 129.811 118.146 142.907 1.00 94.90  ? 502 THR A CG2 1 
ATOM   3985 N  N   . ALA A 1 503 ? 131.875 119.603 145.903 1.00 87.54  ? 503 ALA A N   1 
ATOM   3986 C  CA  . ALA A 1 503 ? 132.426 118.954 147.108 1.00 87.71  ? 503 ALA A CA  1 
ATOM   3987 C  C   . ALA A 1 503 ? 131.944 119.634 148.398 1.00 94.42  ? 503 ALA A C   1 
ATOM   3988 O  O   . ALA A 1 503 ? 131.796 118.933 149.368 1.00 100.65 ? 503 ALA A O   1 
ATOM   3989 C  CB  . ALA A 1 503 ? 133.941 118.847 147.004 1.00 88.47  ? 503 ALA A CB  1 
ATOM   3990 N  N   . ALA A 1 504 ? 131.731 120.945 148.390 1.00 91.07  ? 504 ALA A N   1 
ATOM   3991 C  CA  . ALA A 1 504 ? 131.139 121.600 149.553 1.00 92.09  ? 504 ALA A CA  1 
ATOM   3992 C  C   . ALA A 1 504 ? 129.665 121.246 149.695 1.00 95.11  ? 504 ALA A C   1 
ATOM   3993 O  O   . ALA A 1 504 ? 129.182 121.014 150.809 1.00 100.80 ? 504 ALA A O   1 
ATOM   3994 C  CB  . ALA A 1 504 ? 131.323 123.112 149.452 1.00 88.37  ? 504 ALA A CB  1 
ATOM   3995 N  N   . PHE A 1 505 ? 128.938 121.199 148.577 1.00 95.15  ? 505 PHE A N   1 
ATOM   3996 C  CA  . PHE A 1 505 ? 127.532 120.816 148.608 1.00 94.70  ? 505 PHE A CA  1 
ATOM   3997 C  C   . PHE A 1 505 ? 127.363 119.407 149.149 1.00 101.90 ? 505 PHE A C   1 
ATOM   3998 O  O   . PHE A 1 505 ? 126.497 119.153 149.994 1.00 110.04 ? 505 PHE A O   1 
ATOM   3999 C  CB  . PHE A 1 505 ? 126.937 120.914 147.204 1.00 93.23  ? 505 PHE A CB  1 
ATOM   4000 C  CG  . PHE A 1 505 ? 126.198 122.190 146.943 1.00 102.18 ? 505 PHE A CG  1 
ATOM   4001 C  CD1 . PHE A 1 505 ? 126.861 123.302 146.463 1.00 105.00 ? 505 PHE A CD1 1 
ATOM   4002 C  CD2 . PHE A 1 505 ? 124.835 122.270 147.160 1.00 107.84 ? 505 PHE A CD2 1 
ATOM   4003 C  CE1 . PHE A 1 505 ? 126.186 124.474 146.215 1.00 108.04 ? 505 PHE A CE1 1 
ATOM   4004 C  CE2 . PHE A 1 505 ? 124.153 123.439 146.912 1.00 106.99 ? 505 PHE A CE2 1 
ATOM   4005 C  CZ  . PHE A 1 505 ? 124.832 124.543 146.437 1.00 107.47 ? 505 PHE A CZ  1 
ATOM   4006 N  N   . ALA A 1 506 ? 128.177 118.470 148.661 1.00 94.10  ? 506 ALA A N   1 
ATOM   4007 C  CA  . ALA A 1 506 ? 128.078 117.091 149.126 1.00 92.94  ? 506 ALA A CA  1 
ATOM   4008 C  C   . ALA A 1 506 ? 128.412 116.986 150.608 1.00 94.90  ? 506 ALA A C   1 
ATOM   4009 O  O   . ALA A 1 506 ? 127.725 116.282 151.355 1.00 102.38 ? 506 ALA A O   1 
ATOM   4010 C  CB  . ALA A 1 506 ? 128.998 116.193 148.303 1.00 92.43  ? 506 ALA A CB  1 
ATOM   4011 N  N   . PHE A 1 507 ? 129.460 117.687 151.050 1.00 90.79  ? 507 PHE A N   1 
ATOM   4012 C  CA  . PHE A 1 507 ? 129.832 117.655 152.459 1.00 95.27  ? 507 PHE A CA  1 
ATOM   4013 C  C   . PHE A 1 507 ? 128.709 118.196 153.334 1.00 99.88  ? 507 PHE A C   1 
ATOM   4014 O  O   . PHE A 1 507 ? 128.342 117.586 154.346 1.00 99.79  ? 507 PHE A O   1 
ATOM   4015 C  CB  . PHE A 1 507 ? 131.120 118.454 152.666 1.00 88.58  ? 507 PHE A CB  1 
ATOM   4016 C  CG  . PHE A 1 507 ? 131.651 118.404 154.068 1.00 92.41  ? 507 PHE A CG  1 
ATOM   4017 C  CD1 . PHE A 1 507 ? 132.391 117.320 154.502 1.00 94.83  ? 507 PHE A CD1 1 
ATOM   4018 C  CD2 . PHE A 1 507 ? 131.415 119.444 154.949 1.00 96.46  ? 507 PHE A CD2 1 
ATOM   4019 C  CE1 . PHE A 1 507 ? 132.880 117.272 155.790 1.00 95.37  ? 507 PHE A CE1 1 
ATOM   4020 C  CE2 . PHE A 1 507 ? 131.903 119.400 156.239 1.00 98.93  ? 507 PHE A CE2 1 
ATOM   4021 C  CZ  . PHE A 1 507 ? 132.636 118.311 156.659 1.00 97.74  ? 507 PHE A CZ  1 
ATOM   4022 N  N   . VAL A 1 508 ? 128.125 119.330 152.939 1.00 103.42 ? 508 VAL A N   1 
ATOM   4023 C  CA  . VAL A 1 508 ? 127.059 119.936 153.729 1.00 98.03  ? 508 VAL A CA  1 
ATOM   4024 C  C   . VAL A 1 508 ? 125.828 119.038 153.751 1.00 99.57  ? 508 VAL A C   1 
ATOM   4025 O  O   . VAL A 1 508 ? 125.210 118.832 154.802 1.00 103.97 ? 508 VAL A O   1 
ATOM   4026 C  CB  . VAL A 1 508 ? 126.731 121.341 153.190 1.00 97.29  ? 508 VAL A CB  1 
ATOM   4027 C  CG1 . VAL A 1 508 ? 125.409 121.833 153.745 1.00 99.04  ? 508 VAL A CG1 1 
ATOM   4028 C  CG2 . VAL A 1 508 ? 127.847 122.310 153.533 1.00 98.45  ? 508 VAL A CG2 1 
ATOM   4029 N  N   . PHE A 1 509 ? 125.455 118.482 152.594 1.00 101.75 ? 509 PHE A N   1 
ATOM   4030 C  CA  . PHE A 1 509 ? 124.270 117.632 152.531 1.00 103.98 ? 509 PHE A CA  1 
ATOM   4031 C  C   . PHE A 1 509 ? 124.447 116.367 153.358 1.00 111.10 ? 509 PHE A C   1 
ATOM   4032 O  O   . PHE A 1 509 ? 123.513 115.929 154.040 1.00 117.75 ? 509 PHE A O   1 
ATOM   4033 C  CB  . PHE A 1 509 ? 123.949 117.280 151.079 1.00 106.60 ? 509 PHE A CB  1 
ATOM   4034 C  CG  . PHE A 1 509 ? 123.345 118.412 150.305 1.00 110.04 ? 509 PHE A CG  1 
ATOM   4035 C  CD1 . PHE A 1 509 ? 122.584 119.375 150.943 1.00 103.40 ? 509 PHE A CD1 1 
ATOM   4036 C  CD2 . PHE A 1 509 ? 123.533 118.511 148.936 1.00 114.94 ? 509 PHE A CD2 1 
ATOM   4037 C  CE1 . PHE A 1 509 ? 122.024 120.418 150.234 1.00 106.63 ? 509 PHE A CE1 1 
ATOM   4038 C  CE2 . PHE A 1 509 ? 122.975 119.550 148.222 1.00 111.48 ? 509 PHE A CE2 1 
ATOM   4039 C  CZ  . PHE A 1 509 ? 122.220 120.506 148.872 1.00 110.92 ? 509 PHE A CZ  1 
ATOM   4040 N  N   . TYR A 1 510 ? 125.633 115.753 153.305 1.00 109.01 ? 510 TYR A N   1 
ATOM   4041 C  CA  . TYR A 1 510 ? 125.872 114.575 154.130 1.00 108.95 ? 510 TYR A CA  1 
ATOM   4042 C  C   . TYR A 1 510 ? 125.849 114.926 155.611 1.00 111.11 ? 510 TYR A C   1 
ATOM   4043 O  O   . TYR A 1 510 ? 125.309 114.166 156.424 1.00 115.38 ? 510 TYR A O   1 
ATOM   4044 C  CB  . TYR A 1 510 ? 127.200 113.921 153.762 1.00 109.00 ? 510 TYR A CB  1 
ATOM   4045 C  CG  . TYR A 1 510 ? 127.657 112.920 154.794 1.00 111.51 ? 510 TYR A CG  1 
ATOM   4046 C  CD1 . TYR A 1 510 ? 126.972 111.729 154.983 1.00 111.79 ? 510 TYR A CD1 1 
ATOM   4047 C  CD2 . TYR A 1 510 ? 128.760 113.175 155.598 1.00 112.43 ? 510 TYR A CD2 1 
ATOM   4048 C  CE1 . TYR A 1 510 ? 127.379 110.814 155.931 1.00 112.13 ? 510 TYR A CE1 1 
ATOM   4049 C  CE2 . TYR A 1 510 ? 129.173 112.265 156.548 1.00 114.87 ? 510 TYR A CE2 1 
ATOM   4050 C  CZ  . TYR A 1 510 ? 128.480 111.088 156.711 1.00 117.57 ? 510 TYR A CZ  1 
ATOM   4051 O  OH  . TYR A 1 510 ? 128.886 110.176 157.657 1.00 120.33 ? 510 TYR A OH  1 
ATOM   4052 N  N   . ASN A 1 511 ? 126.298 116.103 155.982 1.00 102.81 ? 511 ASN A N   1 
ATOM   4053 C  CA  . ASN A 1 511 ? 126.411 116.346 157.430 1.00 100.74 ? 511 ASN A CA  1 
ATOM   4054 C  C   . ASN A 1 511 ? 125.066 116.863 157.942 1.00 102.99 ? 511 ASN A C   1 
ATOM   4055 O  O   . ASN A 1 511 ? 124.844 116.791 159.138 1.00 105.24 ? 511 ASN A O   1 
ATOM   4056 C  CB  . ASN A 1 511 ? 127.612 117.240 157.752 1.00 104.88 ? 511 ASN A CB  1 
ATOM   4057 C  CG  . ASN A 1 511 ? 128.950 116.559 157.589 1.00 104.92 ? 511 ASN A CG  1 
ATOM   4058 O  OD1 . ASN A 1 511 ? 129.394 116.310 156.474 1.00 105.77 ? 511 ASN A OD1 1 
ATOM   4059 N  ND2 . ASN A 1 511 ? 129.619 116.296 158.696 1.00 101.05 ? 511 ASN A ND2 1 
ATOM   4060 N  N   . MET A 1 512 ? 124.188 117.322 157.059 1.00 107.13 ? 512 MET A N   1 
ATOM   4061 C  CA  . MET A 1 512 ? 122.806 117.576 157.440 1.00 107.01 ? 512 MET A CA  1 
ATOM   4062 C  C   . MET A 1 512 ? 121.937 116.327 157.391 1.00 112.14 ? 512 MET A C   1 
ATOM   4063 O  O   . MET A 1 512 ? 120.788 116.377 157.843 1.00 115.90 ? 512 MET A O   1 
ATOM   4064 C  CB  . MET A 1 512 ? 122.194 118.649 156.537 1.00 105.28 ? 512 MET A CB  1 
ATOM   4065 C  CG  . MET A 1 512 ? 122.875 120.001 156.616 1.00 106.05 ? 512 MET A CG  1 
ATOM   4066 S  SD  . MET A 1 512 ? 121.734 121.348 156.260 1.00 116.41 ? 512 MET A SD  1 
ATOM   4067 C  CE  . MET A 1 512 ? 122.854 122.741 156.240 1.00 109.48 ? 512 MET A CE  1 
ATOM   4068 N  N   . GLY A 1 513 ? 122.447 115.220 156.860 1.00 118.89 ? 513 GLY A N   1 
ATOM   4069 C  CA  . GLY A 1 513 ? 121.668 114.001 156.779 1.00 116.74 ? 513 GLY A CA  1 
ATOM   4070 C  C   . GLY A 1 513 ? 120.709 113.929 155.617 1.00 119.38 ? 513 GLY A C   1 
ATOM   4071 O  O   . GLY A 1 513 ? 119.716 113.201 155.696 1.00 121.04 ? 513 GLY A O   1 
ATOM   4072 N  N   . PHE A 1 514 ? 120.966 114.667 154.537 1.00 116.78 ? 514 PHE A N   1 
ATOM   4073 C  CA  . PHE A 1 514 ? 120.070 114.647 153.390 1.00 115.99 ? 514 PHE A CA  1 
ATOM   4074 C  C   . PHE A 1 514 ? 120.398 113.524 152.414 1.00 118.30 ? 514 PHE A C   1 
ATOM   4075 O  O   . PHE A 1 514 ? 119.502 113.039 151.715 1.00 123.31 ? 514 PHE A O   1 
ATOM   4076 C  CB  . PHE A 1 514 ? 120.115 115.989 152.663 1.00 114.15 ? 514 PHE A CB  1 
ATOM   4077 C  CG  . PHE A 1 514 ? 119.447 117.100 153.411 1.00 118.07 ? 514 PHE A CG  1 
ATOM   4078 C  CD1 . PHE A 1 514 ? 118.178 116.931 153.930 1.00 117.39 ? 514 PHE A CD1 1 
ATOM   4079 C  CD2 . PHE A 1 514 ? 120.087 118.312 153.596 1.00 121.57 ? 514 PHE A CD2 1 
ATOM   4080 C  CE1 . PHE A 1 514 ? 117.556 117.949 154.622 1.00 118.56 ? 514 PHE A CE1 1 
ATOM   4081 C  CE2 . PHE A 1 514 ? 119.470 119.335 154.285 1.00 121.18 ? 514 PHE A CE2 1 
ATOM   4082 C  CZ  . PHE A 1 514 ? 118.205 119.154 154.800 1.00 119.77 ? 514 PHE A CZ  1 
ATOM   4083 N  N   . VAL A 1 515 ? 121.674 113.113 152.441 1.00 116.60 ? 515 VAL A N   1 
ATOM   4084 C  CA  . VAL A 1 515 ? 122.151 112.124 151.448 1.00 116.30 ? 515 VAL A CA  1 
ATOM   4085 C  C   . VAL A 1 515 ? 122.971 111.069 152.156 1.00 115.33 ? 515 VAL A C   1 
ATOM   4086 O  O   . VAL A 1 515 ? 123.373 111.340 153.273 1.00 117.60 ? 515 VAL A O   1 
ATOM   4087 C  CB  . VAL A 1 515 ? 122.969 112.812 150.323 1.00 116.34 ? 515 VAL A CB  1 
ATOM   4088 C  CG1 . VAL A 1 515 ? 122.096 113.640 149.398 1.00 115.83 ? 515 VAL A CG1 1 
ATOM   4089 C  CG2 . VAL A 1 515 ? 124.121 113.643 150.851 1.00 117.74 ? 515 VAL A CG2 1 
ATOM   4090 N  N   . ARG A 1 516 ? 123.151 109.939 151.540 1.00 127.19 ? 516 ARG A N   1 
ATOM   4091 C  CA  . ARG A 1 516 ? 124.007 108.911 152.138 1.00 129.72 ? 516 ARG A CA  1 
ATOM   4092 C  C   . ARG A 1 516 ? 125.463 109.298 151.910 1.00 132.19 ? 516 ARG A C   1 
ATOM   4093 O  O   . ARG A 1 516 ? 125.716 110.130 151.050 1.00 133.20 ? 516 ARG A O   1 
ATOM   4094 C  CB  . ARG A 1 516 ? 123.630 107.581 151.503 1.00 131.34 ? 516 ARG A CB  1 
ATOM   4095 C  CG  . ARG A 1 516 ? 122.278 107.621 150.814 1.00 130.16 ? 516 ARG A CG  1 
ATOM   4096 C  CD  . ARG A 1 516 ? 121.217 107.621 151.894 1.00 135.17 ? 516 ARG A CD  1 
ATOM   4097 N  NE  . ARG A 1 516 ? 121.514 106.602 152.887 1.00 139.16 ? 516 ARG A NE  1 
ATOM   4098 C  CZ  . ARG A 1 516 ? 121.362 105.300 152.681 1.00 137.00 ? 516 ARG A CZ  1 
ATOM   4099 N  NH1 . ARG A 1 516 ? 121.296 104.833 151.447 1.00 135.59 ? 516 ARG A NH1 1 
ATOM   4100 N  NH2 . ARG A 1 516 ? 121.271 104.470 153.704 1.00 133.25 ? 516 ARG A NH2 1 
ATOM   4101 N  N   . ARG A 1 517 ? 126.364 108.741 152.697 1.00 120.55 ? 517 ARG A N   1 
ATOM   4102 C  CA  . ARG A 1 517 ? 127.794 108.975 152.534 1.00 117.93 ? 517 ARG A CA  1 
ATOM   4103 C  C   . ARG A 1 517 ? 128.290 108.408 151.211 1.00 117.85 ? 517 ARG A C   1 
ATOM   4104 O  O   . ARG A 1 517 ? 129.033 109.069 150.477 1.00 119.98 ? 517 ARG A O   1 
ATOM   4105 C  CB  . ARG A 1 517 ? 128.559 108.363 153.707 1.00 116.00 ? 517 ARG A CB  1 
ATOM   4106 C  CG  . ARG A 1 517 ? 130.036 108.698 153.722 1.00 116.73 ? 517 ARG A CG  1 
ATOM   4107 C  CD  . ARG A 1 517 ? 130.781 107.842 154.730 1.00 120.08 ? 517 ARG A CD  1 
ATOM   4108 N  NE  . ARG A 1 517 ? 131.087 108.576 155.952 1.00 119.85 ? 517 ARG A NE  1 
ATOM   4109 C  CZ  . ARG A 1 517 ? 131.928 109.598 156.032 1.00 120.16 ? 517 ARG A CZ  1 
ATOM   4110 N  NH1 . ARG A 1 517 ? 132.606 110.023 154.980 1.00 120.61 ? 517 ARG A NH1 1 
ATOM   4111 N  NH2 . ARG A 1 517 ? 132.100 110.206 157.203 1.00 124.49 ? 517 ARG A NH2 1 
ATOM   4112 N  N   . SER A 1 518 ? 127.878 107.179 150.887 1.00 116.67 ? 518 SER A N   1 
ATOM   4113 C  CA  . SER A 1 518 ? 128.294 106.568 149.630 1.00 119.03 ? 518 SER A CA  1 
ATOM   4114 C  C   . SER A 1 518 ? 127.762 107.346 148.436 1.00 116.76 ? 518 SER A C   1 
ATOM   4115 O  O   . SER A 1 518 ? 128.486 107.571 147.459 1.00 118.30 ? 518 SER A O   1 
ATOM   4116 C  CB  . SER A 1 518 ? 127.823 105.115 149.572 1.00 120.31 ? 518 SER A CB  1 
ATOM   4117 O  OG  . SER A 1 518 ? 126.409 105.043 149.554 1.00 119.19 ? 518 SER A OG  1 
ATOM   4118 N  N   . THR A 1 519 ? 126.496 107.762 148.496 1.00 111.53 ? 519 THR A N   1 
ATOM   4119 C  CA  . THR A 1 519 ? 125.913 108.528 147.402 1.00 112.97 ? 519 THR A CA  1 
ATOM   4120 C  C   . THR A 1 519 ? 126.663 109.836 147.193 1.00 114.04 ? 519 THR A C   1 
ATOM   4121 O  O   . THR A 1 519 ? 127.020 110.188 146.063 1.00 116.84 ? 519 THR A O   1 
ATOM   4122 C  CB  . THR A 1 519 ? 124.432 108.792 147.680 1.00 115.19 ? 519 THR A CB  1 
ATOM   4123 O  OG1 . THR A 1 519 ? 123.684 107.588 147.473 1.00 121.69 ? 519 THR A OG1 1 
ATOM   4124 C  CG2 . THR A 1 519 ? 123.896 109.878 146.763 1.00 111.65 ? 519 THR A CG2 1 
ATOM   4125 N  N   . ALA A 1 520 ? 126.931 110.562 148.282 1.00 105.19 ? 520 ALA A N   1 
ATOM   4126 C  CA  . ALA A 1 520 ? 127.641 111.831 148.170 1.00 99.87  ? 520 ALA A CA  1 
ATOM   4127 C  C   . ALA A 1 520 ? 129.047 111.634 147.619 1.00 102.86 ? 520 ALA A C   1 
ATOM   4128 O  O   . ALA A 1 520 ? 129.483 112.376 146.732 1.00 106.03 ? 520 ALA A O   1 
ATOM   4129 C  CB  . ALA A 1 520 ? 127.689 112.527 149.527 1.00 100.49 ? 520 ALA A CB  1 
ATOM   4130 N  N   . THR A 1 521 ? 129.767 110.625 148.121 1.00 103.39 ? 521 THR A N   1 
ATOM   4131 C  CA  . THR A 1 521 ? 131.136 110.398 147.672 1.00 99.37  ? 521 THR A CA  1 
ATOM   4132 C  C   . THR A 1 521 ? 131.175 110.032 146.194 1.00 96.66  ? 521 THR A C   1 
ATOM   4133 O  O   . THR A 1 521 ? 131.974 110.585 145.425 1.00 94.51  ? 521 THR A O   1 
ATOM   4134 C  CB  . THR A 1 521 ? 131.787 109.301 148.513 1.00 103.58 ? 521 THR A CB  1 
ATOM   4135 O  OG1 . THR A 1 521 ? 131.785 109.688 149.892 1.00 106.98 ? 521 THR A OG1 1 
ATOM   4136 C  CG2 . THR A 1 521 ? 133.219 109.072 148.067 1.00 103.51 ? 521 THR A CG2 1 
ATOM   4137 N  N   . ALA A 1 522 ? 130.313 109.101 145.774 1.00 96.46  ? 522 ALA A N   1 
ATOM   4138 C  CA  . ALA A 1 522 ? 130.304 108.681 144.378 1.00 95.60  ? 522 ALA A CA  1 
ATOM   4139 C  C   . ALA A 1 522 ? 129.893 109.824 143.460 1.00 94.49  ? 522 ALA A C   1 
ATOM   4140 O  O   . ALA A 1 522 ? 130.496 110.020 142.396 1.00 101.10 ? 522 ALA A O   1 
ATOM   4141 C  CB  . ALA A 1 522 ? 129.370 107.485 144.199 1.00 97.78  ? 522 ALA A CB  1 
ATOM   4142 N  N   . SER A 1 523 ? 128.876 110.595 143.852 1.00 96.45  ? 523 SER A N   1 
ATOM   4143 C  CA  . SER A 1 523 ? 128.439 111.718 143.032 1.00 97.49  ? 523 SER A CA  1 
ATOM   4144 C  C   . SER A 1 523 ? 129.544 112.755 142.893 1.00 97.72  ? 523 SER A C   1 
ATOM   4145 O  O   . SER A 1 523 ? 129.792 113.270 141.799 1.00 104.55 ? 523 SER A O   1 
ATOM   4146 C  CB  . SER A 1 523 ? 127.182 112.346 143.630 1.00 99.33  ? 523 SER A CB  1 
ATOM   4147 O  OG  . SER A 1 523 ? 126.094 111.440 143.593 1.00 101.19 ? 523 SER A OG  1 
ATOM   4148 N  N   . THR A 1 524 ? 130.233 113.066 143.995 1.00 93.51  ? 524 THR A N   1 
ATOM   4149 C  CA  . THR A 1 524 ? 131.307 114.050 143.935 1.00 94.23  ? 524 THR A CA  1 
ATOM   4150 C  C   . THR A 1 524 ? 132.458 113.566 143.061 1.00 97.65  ? 524 THR A C   1 
ATOM   4151 O  O   . THR A 1 524 ? 132.991 114.332 142.252 1.00 94.53  ? 524 THR A O   1 
ATOM   4152 C  CB  . THR A 1 524 ? 131.806 114.369 145.343 1.00 96.80  ? 524 THR A CB  1 
ATOM   4153 O  OG1 . THR A 1 524 ? 130.691 114.432 146.238 1.00 96.79  ? 524 THR A OG1 1 
ATOM   4154 C  CG2 . THR A 1 524 ? 132.534 115.698 145.359 1.00 98.08  ? 524 THR A CG2 1 
ATOM   4155 N  N   . LEU A 1 525 ? 132.848 112.297 143.203 1.00 95.98  ? 525 LEU A N   1 
ATOM   4156 C  CA  . LEU A 1 525 ? 133.951 111.774 142.402 1.00 88.54  ? 525 LEU A CA  1 
ATOM   4157 C  C   . LEU A 1 525 ? 133.602 111.772 140.918 1.00 87.15  ? 525 LEU A C   1 
ATOM   4158 O  O   . LEU A 1 525 ? 134.411 112.187 140.076 1.00 92.13  ? 525 LEU A O   1 
ATOM   4159 C  CB  . LEU A 1 525 ? 134.316 110.368 142.876 1.00 90.98  ? 525 LEU A CB  1 
ATOM   4160 C  CG  . LEU A 1 525 ? 135.227 110.289 144.104 1.00 90.00  ? 525 LEU A CG  1 
ATOM   4161 C  CD1 . LEU A 1 525 ? 135.471 108.845 144.506 1.00 93.70  ? 525 LEU A CD1 1 
ATOM   4162 C  CD2 . LEU A 1 525 ? 136.542 110.998 143.838 1.00 86.47  ? 525 LEU A CD2 1 
ATOM   4163 N  N   . ALA A 1 526 ? 132.393 111.319 140.578 1.00 85.17  ? 526 ALA A N   1 
ATOM   4164 C  CA  . ALA A 1 526 ? 131.981 111.304 139.179 1.00 82.09  ? 526 ALA A CA  1 
ATOM   4165 C  C   . ALA A 1 526 ? 131.892 112.716 138.612 1.00 89.34  ? 526 ALA A C   1 
ATOM   4166 O  O   . ALA A 1 526 ? 132.326 112.967 137.482 1.00 95.06  ? 526 ALA A O   1 
ATOM   4167 C  CB  . ALA A 1 526 ? 130.643 110.582 139.033 1.00 85.96  ? 526 ALA A CB  1 
ATOM   4168 N  N   . ALA A 1 527 ? 131.330 113.651 139.383 1.00 95.22  ? 527 ALA A N   1 
ATOM   4169 C  CA  . ALA A 1 527 ? 131.223 115.026 138.913 1.00 93.41  ? 527 ALA A CA  1 
ATOM   4170 C  C   . ALA A 1 527 ? 132.596 115.636 138.687 1.00 94.21  ? 527 ALA A C   1 
ATOM   4171 O  O   . ALA A 1 527 ? 132.813 116.329 137.690 1.00 101.82 ? 527 ALA A O   1 
ATOM   4172 C  CB  . ALA A 1 527 ? 130.417 115.861 139.909 1.00 94.81  ? 527 ALA A CB  1 
ATOM   4173 N  N   . ALA A 1 528 ? 133.538 115.384 139.599 1.00 86.38  ? 528 ALA A N   1 
ATOM   4174 C  CA  . ALA A 1 528 ? 134.890 115.898 139.417 1.00 87.70  ? 528 ALA A CA  1 
ATOM   4175 C  C   . ALA A 1 528 ? 135.539 115.311 138.172 1.00 89.36  ? 528 ALA A C   1 
ATOM   4176 O  O   . ALA A 1 528 ? 136.188 116.030 137.402 1.00 94.04  ? 528 ALA A O   1 
ATOM   4177 C  CB  . ALA A 1 528 ? 135.736 115.601 140.655 1.00 89.20  ? 528 ALA A CB  1 
ATOM   4178 N  N   . ALA A 1 529 ? 135.369 114.003 137.955 1.00 89.15  ? 529 ALA A N   1 
ATOM   4179 C  CA  . ALA A 1 529 ? 135.957 113.374 136.777 1.00 84.06  ? 529 ALA A CA  1 
ATOM   4180 C  C   . ALA A 1 529 ? 135.394 113.969 135.491 1.00 84.92  ? 529 ALA A C   1 
ATOM   4181 O  O   . ALA A 1 529 ? 136.150 114.289 134.565 1.00 87.78  ? 529 ALA A O   1 
ATOM   4182 C  CB  . ALA A 1 529 ? 135.728 111.865 136.817 1.00 84.59  ? 529 ALA A CB  1 
ATOM   4183 N  N   . ILE A 1 530 ? 134.100 114.237 135.410 1.00 94.65  ? 530 ILE A N   1 
ATOM   4184 C  CA  . ILE A 1 530 ? 133.405 114.741 134.191 1.00 95.06  ? 530 ILE A CA  1 
ATOM   4185 C  C   . ILE A 1 530 ? 133.735 116.210 133.966 1.00 98.10  ? 530 ILE A C   1 
ATOM   4186 O  O   . ILE A 1 530 ? 133.875 116.624 132.828 1.00 104.10 ? 530 ILE A O   1 
ATOM   4187 C  CB  . ILE A 1 530 ? 131.883 114.515 134.332 1.00 95.09  ? 530 ILE A CB  1 
ATOM   4188 C  CG1 . ILE A 1 530 ? 131.526 113.028 134.375 1.00 99.34  ? 530 ILE A CG1 1 
ATOM   4189 C  CG2 . ILE A 1 530 ? 131.119 115.244 133.244 1.00 98.71  ? 530 ILE A CG2 1 
ATOM   4190 C  CD1 . ILE A 1 530 ? 130.203 112.735 135.026 1.00 100.72 ? 530 ILE A CD1 1 
ATOM   4191 N  N   . PHE A 1 531 ? 133.806 116.960 135.047 1.00 98.31  ? 531 PHE A N   1 
ATOM   4192 C  CA  . PHE A 1 531 ? 134.263 118.363 134.928 1.00 93.96  ? 531 PHE A CA  1 
ATOM   4193 C  C   . PHE A 1 531 ? 135.722 118.451 134.474 1.00 95.27  ? 531 PHE A C   1 
ATOM   4194 O  O   . PHE A 1 531 ? 135.999 119.323 133.683 1.00 96.80  ? 531 PHE A O   1 
ATOM   4195 C  CB  . PHE A 1 531 ? 134.142 119.108 136.252 1.00 98.69  ? 531 PHE A CB  1 
ATOM   4196 C  CG  . PHE A 1 531 ? 132.762 119.383 136.785 1.00 100.56 ? 531 PHE A CG  1 
ATOM   4197 C  CD1 . PHE A 1 531 ? 131.724 119.737 135.945 1.00 103.72 ? 531 PHE A CD1 1 
ATOM   4198 C  CD2 . PHE A 1 531 ? 132.524 119.349 138.148 1.00 101.23 ? 531 PHE A CD2 1 
ATOM   4199 C  CE1 . PHE A 1 531 ? 130.465 120.004 136.454 1.00 108.19 ? 531 PHE A CE1 1 
ATOM   4200 C  CE2 . PHE A 1 531 ? 131.265 119.617 138.658 1.00 102.60 ? 531 PHE A CE2 1 
ATOM   4201 C  CZ  . PHE A 1 531 ? 130.238 119.945 137.809 1.00 106.15 ? 531 PHE A CZ  1 
ATOM   4202 N  N   . MET A 1 532 ? 136.628 117.619 134.984 1.00 95.97  ? 532 MET A N   1 
ATOM   4203 C  CA  . MET A 1 532 ? 138.006 117.664 134.506 1.00 93.24  ? 532 MET A CA  1 
ATOM   4204 C  C   . MET A 1 532 ? 138.098 117.211 133.055 1.00 91.69  ? 532 MET A C   1 
ATOM   4205 O  O   . MET A 1 532 ? 138.840 117.797 132.259 1.00 93.62  ? 532 MET A O   1 
ATOM   4206 C  CB  . MET A 1 532 ? 138.894 116.802 135.403 1.00 98.44  ? 532 MET A CB  1 
ATOM   4207 C  CG  . MET A 1 532 ? 139.293 117.455 136.723 1.00 100.98 ? 532 MET A CG  1 
ATOM   4208 S  SD  . MET A 1 532 ? 139.997 119.110 136.570 1.00 108.80 ? 532 MET A SD  1 
ATOM   4209 C  CE  . MET A 1 532 ? 138.598 120.142 137.000 1.00 90.27  ? 532 MET A CE  1 
ATOM   4210 N  N   . LEU A 1 533 ? 137.349 116.166 132.689 1.00 96.69  ? 533 LEU A N   1 
ATOM   4211 C  CA  . LEU A 1 533 ? 137.404 115.658 131.323 1.00 93.69  ? 533 LEU A CA  1 
ATOM   4212 C  C   . LEU A 1 533 ? 136.910 116.695 130.325 1.00 89.09  ? 533 LEU A C   1 
ATOM   4213 O  O   . LEU A 1 533 ? 137.506 116.869 129.255 1.00 96.09  ? 533 LEU A O   1 
ATOM   4214 C  CB  . LEU A 1 533 ? 136.586 114.373 131.208 1.00 98.23  ? 533 LEU A CB  1 
ATOM   4215 C  CG  . LEU A 1 533 ? 136.446 113.781 129.803 1.00 97.02  ? 533 LEU A CG  1 
ATOM   4216 C  CD1 . LEU A 1 533 ? 137.751 113.152 129.354 1.00 95.85  ? 533 LEU A CD1 1 
ATOM   4217 C  CD2 . LEU A 1 533 ? 135.320 112.765 129.764 1.00 99.51  ? 533 LEU A CD2 1 
ATOM   4218 N  N   . GLY A 1 534 ? 135.824 117.390 130.651 1.00 87.22  ? 534 GLY A N   1 
ATOM   4219 C  CA  . GLY A 1 534 ? 135.304 118.397 129.751 1.00 91.69  ? 534 GLY A CA  1 
ATOM   4220 C  C   . GLY A 1 534 ? 135.922 119.770 129.865 1.00 93.07  ? 534 GLY A C   1 
ATOM   4221 O  O   . GLY A 1 534 ? 135.724 120.599 128.973 1.00 97.05  ? 534 GLY A O   1 
ATOM   4222 N  N   . GLY A 1 535 ? 136.671 120.037 130.929 1.00 91.26  ? 535 GLY A N   1 
ATOM   4223 C  CA  . GLY A 1 535 ? 137.174 121.377 131.162 1.00 90.45  ? 535 GLY A CA  1 
ATOM   4224 C  C   . GLY A 1 535 ? 138.653 121.575 130.899 1.00 87.64  ? 535 GLY A C   1 
ATOM   4225 O  O   . GLY A 1 535 ? 139.048 122.608 130.354 1.00 86.44  ? 535 GLY A O   1 
ATOM   4226 N  N   . VAL A 1 536 ? 139.481 120.601 131.282 1.00 89.24  ? 536 VAL A N   1 
ATOM   4227 C  CA  . VAL A 1 536 ? 140.928 120.753 131.114 1.00 82.33  ? 536 VAL A CA  1 
ATOM   4228 C  C   . VAL A 1 536 ? 141.325 120.872 129.646 1.00 85.43  ? 536 VAL A C   1 
ATOM   4229 O  O   . VAL A 1 536 ? 142.051 121.819 129.301 1.00 95.68  ? 536 VAL A O   1 
ATOM   4230 C  CB  . VAL A 1 536 ? 141.670 119.620 131.842 1.00 88.95  ? 536 VAL A CB  1 
ATOM   4231 C  CG1 . VAL A 1 536 ? 143.144 119.630 131.473 1.00 86.70  ? 536 VAL A CG1 1 
ATOM   4232 C  CG2 . VAL A 1 536 ? 141.495 119.752 133.342 1.00 93.26  ? 536 VAL A CG2 1 
ATOM   4233 N  N   . PRO A 1 537 ? 140.898 119.984 128.739 1.00 88.37  ? 537 PRO A N   1 
ATOM   4234 C  CA  . PRO A 1 537 ? 141.233 120.182 127.323 1.00 84.77  ? 537 PRO A CA  1 
ATOM   4235 C  C   . PRO A 1 537 ? 140.322 121.167 126.613 1.00 87.70  ? 537 PRO A C   1 
ATOM   4236 O  O   . PRO A 1 537 ? 140.611 121.532 125.465 1.00 95.16  ? 537 PRO A O   1 
ATOM   4237 C  CB  . PRO A 1 537 ? 141.093 118.776 126.734 1.00 87.90  ? 537 PRO A CB  1 
ATOM   4238 C  CG  . PRO A 1 537 ? 140.065 118.138 127.571 1.00 95.58  ? 537 PRO A CG  1 
ATOM   4239 C  CD  . PRO A 1 537 ? 140.167 118.720 128.947 1.00 98.31  ? 537 PRO A CD  1 
ATOM   4240 N  N   . GLY A 1 538 ? 139.242 121.613 127.254 1.00 83.19  ? 538 GLY A N   1 
ATOM   4241 C  CA  . GLY A 1 538 ? 138.395 122.641 126.684 1.00 85.13  ? 538 GLY A CA  1 
ATOM   4242 C  C   . GLY A 1 538 ? 138.965 124.035 126.758 1.00 87.64  ? 538 GLY A C   1 
ATOM   4243 O  O   . GLY A 1 538 ? 138.370 124.968 126.215 1.00 95.54  ? 538 GLY A O   1 
ATOM   4244 N  N   . THR A 1 539 ? 140.115 124.203 127.380 1.00 76.45  ? 539 THR A N   1 
ATOM   4245 C  CA  . THR A 1 539 ? 140.861 125.474 127.473 1.00 72.62  ? 539 THR A CA  1 
ATOM   4246 C  C   . THR A 1 539 ? 141.189 125.962 126.069 1.00 72.65  ? 539 THR A C   1 
ATOM   4247 O  O   . THR A 1 539 ? 141.289 127.155 125.896 1.00 80.98  ? 539 THR A O   1 
ATOM   4248 C  CB  . THR A 1 539 ? 142.088 125.301 128.373 1.00 75.06  ? 539 THR A CB  1 
ATOM   4249 O  OG1 . THR A 1 539 ? 141.671 124.636 129.563 1.00 85.68  ? 539 THR A OG1 1 
ATOM   4250 C  CG2 . THR A 1 539 ? 142.780 126.600 128.718 1.00 78.39  ? 539 THR A CG2 1 
ATOM   4251 N  N   . LEU A 1 540 ? 141.267 125.094 125.094 1.00 71.47  ? 540 LEU A N   1 
ATOM   4252 C  CA  . LEU A 1 540 ? 141.835 125.458 123.787 1.00 74.30  ? 540 LEU A CA  1 
ATOM   4253 C  C   . LEU A 1 540 ? 140.776 126.126 122.918 1.00 73.83  ? 540 LEU A C   1 
ATOM   4254 O  O   . LEU A 1 540 ? 141.141 126.606 121.878 1.00 81.40  ? 540 LEU A O   1 
ATOM   4255 C  CB  . LEU A 1 540 ? 142.393 124.181 123.169 1.00 74.68  ? 540 LEU A CB  1 
ATOM   4256 C  CG  . LEU A 1 540 ? 143.588 123.578 123.897 1.00 73.49  ? 540 LEU A CG  1 
ATOM   4257 C  CD1 . LEU A 1 540 ? 144.023 122.297 123.221 1.00 80.63  ? 540 LEU A CD1 1 
ATOM   4258 C  CD2 . LEU A 1 540 ? 144.737 124.565 123.936 1.00 75.60  ? 540 LEU A CD2 1 
ATOM   4259 N  N   . HIS A 1 541 ? 139.526 126.197 123.350 1.00 68.82  ? 541 HIS A N   1 
ATOM   4260 C  CA  . HIS A 1 541 ? 138.564 126.931 122.535 1.00 72.11  ? 541 HIS A CA  1 
ATOM   4261 C  C   . HIS A 1 541 ? 138.715 128.439 122.673 1.00 79.19  ? 541 HIS A C   1 
ATOM   4262 O  O   . HIS A 1 541 ? 138.050 129.179 121.941 1.00 90.70  ? 541 HIS A O   1 
ATOM   4263 C  CB  . HIS A 1 541 ? 137.123 126.492 122.843 1.00 69.13  ? 541 HIS A CB  1 
ATOM   4264 C  CG  . HIS A 1 541 ? 136.649 126.806 124.228 1.00 75.57  ? 541 HIS A CG  1 
ATOM   4265 N  ND1 . HIS A 1 541 ? 136.012 125.874 125.018 1.00 82.06  ? 541 HIS A ND1 1 
ATOM   4266 C  CD2 . HIS A 1 541 ? 136.680 127.950 124.952 1.00 84.30  ? 541 HIS A CD2 1 
ATOM   4267 C  CE1 . HIS A 1 541 ? 135.687 126.424 126.174 1.00 80.68  ? 541 HIS A CE1 1 
ATOM   4268 N  NE2 . HIS A 1 541 ? 136.084 127.684 126.160 1.00 84.17  ? 541 HIS A NE2 1 
ATOM   4269 N  N   . HIS A 1 542 ? 139.564 128.911 123.585 1.00 64.38  ? 542 HIS A N   1 
ATOM   4270 C  CA  . HIS A 1 542 ? 139.950 130.314 123.631 1.00 69.13  ? 542 HIS A CA  1 
ATOM   4271 C  C   . HIS A 1 542 ? 141.189 130.621 122.803 1.00 74.99  ? 542 HIS A C   1 
ATOM   4272 O  O   . HIS A 1 542 ? 141.596 131.784 122.740 1.00 81.04  ? 542 HIS A O   1 
ATOM   4273 C  CB  . HIS A 1 542 ? 140.199 130.761 125.076 1.00 64.08  ? 542 HIS A CB  1 
ATOM   4274 C  CG  . HIS A 1 542 ? 139.042 130.532 125.996 1.00 62.93  ? 542 HIS A CG  1 
ATOM   4275 N  ND1 . HIS A 1 542 ? 137.989 131.413 126.098 1.00 67.47  ? 542 HIS A ND1 1 
ATOM   4276 C  CD2 . HIS A 1 542 ? 138.783 129.532 126.871 1.00 70.13  ? 542 HIS A CD2 1 
ATOM   4277 C  CE1 . HIS A 1 542 ? 137.124 130.961 126.990 1.00 74.84  ? 542 HIS A CE1 1 
ATOM   4278 N  NE2 . HIS A 1 542 ? 137.582 129.821 127.472 1.00 70.98  ? 542 HIS A NE2 1 
ATOM   4279 N  N   . LEU A 1 543 ? 141.801 129.617 122.172 1.00 72.88  ? 543 LEU A N   1 
ATOM   4280 C  CA  . LEU A 1 543 ? 143.050 129.799 121.442 1.00 74.15  ? 543 LEU A CA  1 
ATOM   4281 C  C   . LEU A 1 543 ? 142.956 129.302 120.003 1.00 74.14  ? 543 LEU A C   1 
ATOM   4282 O  O   . LEU A 1 543 ? 143.960 128.889 119.422 1.00 83.95  ? 543 LEU A O   1 
ATOM   4283 C  CB  . LEU A 1 543 ? 144.203 129.103 122.165 1.00 73.11  ? 543 LEU A CB  1 
ATOM   4284 C  CG  . LEU A 1 543 ? 144.334 129.350 123.667 1.00 72.84  ? 543 LEU A CG  1 
ATOM   4285 C  CD1 . LEU A 1 543 ? 144.964 128.153 124.355 1.00 74.20  ? 543 LEU A CD1 1 
ATOM   4286 C  CD2 . LEU A 1 543 ? 145.152 130.600 123.918 1.00 77.79  ? 543 LEU A CD2 1 
ATOM   4287 N  N   . TYR A 1 544 ? 141.819 129.379 119.365 1.00 74.97  ? 544 TYR A N   1 
ATOM   4288 C  CA  . TYR A 1 544 ? 141.718 128.854 117.990 1.00 75.34  ? 544 TYR A CA  1 
ATOM   4289 C  C   . TYR A 1 544 ? 142.437 129.814 117.053 1.00 77.06  ? 544 TYR A C   1 
ATOM   4290 O  O   . TYR A 1 544 ? 143.024 129.357 116.102 1.00 84.63  ? 544 TYR A O   1 
ATOM   4291 C  CB  . TYR A 1 544 ? 140.273 128.704 117.539 1.00 83.52  ? 544 TYR A CB  1 
ATOM   4292 C  CG  . TYR A 1 544 ? 139.359 127.692 118.163 1.00 81.44  ? 544 TYR A CG  1 
ATOM   4293 C  CD1 . TYR A 1 544 ? 139.818 126.566 118.817 1.00 78.98  ? 544 TYR A CD1 1 
ATOM   4294 C  CD2 . TYR A 1 544 ? 137.994 127.882 118.066 1.00 79.00  ? 544 TYR A CD2 1 
ATOM   4295 C  CE1 . TYR A 1 544 ? 138.933 125.657 119.370 1.00 83.90  ? 544 TYR A CE1 1 
ATOM   4296 C  CE2 . TYR A 1 544 ? 137.098 126.989 118.613 1.00 75.62  ? 544 TYR A CE2 1 
ATOM   4297 C  CZ  . TYR A 1 544 ? 137.572 125.873 119.267 1.00 84.89  ? 544 TYR A CZ  1 
ATOM   4298 O  OH  . TYR A 1 544 ? 136.650 125.021 119.787 1.00 95.82  ? 544 TYR A OH  1 
ATOM   4299 N  N   . PHE A 1 545 ? 142.386 131.112 117.320 1.00 64.60  ? 545 PHE A N   1 
ATOM   4300 C  CA  . PHE A 1 545 ? 142.927 132.101 116.397 1.00 72.23  ? 545 PHE A CA  1 
ATOM   4301 C  C   . PHE A 1 545 ? 143.875 133.049 117.117 1.00 79.72  ? 545 PHE A C   1 
ATOM   4302 O  O   . PHE A 1 545 ? 143.922 134.250 116.846 1.00 84.28  ? 545 PHE A O   1 
ATOM   4303 C  CB  . PHE A 1 545 ? 141.793 132.873 115.734 1.00 74.19  ? 545 PHE A CB  1 
ATOM   4304 C  CG  . PHE A 1 545 ? 140.607 132.025 115.386 1.00 73.42  ? 545 PHE A CG  1 
ATOM   4305 C  CD1 . PHE A 1 545 ? 140.675 131.110 114.352 1.00 74.32  ? 545 PHE A CD1 1 
ATOM   4306 C  CD2 . PHE A 1 545 ? 139.425 132.140 116.096 1.00 76.30  ? 545 PHE A CD2 1 
ATOM   4307 C  CE1 . PHE A 1 545 ? 139.588 130.327 114.030 1.00 72.04  ? 545 PHE A CE1 1 
ATOM   4308 C  CE2 . PHE A 1 545 ? 138.334 131.359 115.779 1.00 72.98  ? 545 PHE A CE2 1 
ATOM   4309 C  CZ  . PHE A 1 545 ? 138.417 130.451 114.744 1.00 71.85  ? 545 PHE A CZ  1 
ATOM   4310 N  N   . SER A 1 546 ? 144.657 132.511 118.050 1.00 90.27  ? 546 SER A N   1 
ATOM   4311 C  CA  . SER A 1 546 ? 145.589 133.303 118.842 1.00 87.55  ? 546 SER A CA  1 
ATOM   4312 C  C   . SER A 1 546 ? 147.036 132.958 118.513 1.00 84.14  ? 546 SER A C   1 
ATOM   4313 O  O   . SER A 1 546 ? 147.925 133.108 119.354 1.00 88.68  ? 546 SER A O   1 
ATOM   4314 C  CB  . SER A 1 546 ? 145.321 133.113 120.334 1.00 87.20  ? 546 SER A CB  1 
ATOM   4315 O  OG  . SER A 1 546 ? 144.103 133.727 120.714 1.00 89.35  ? 546 SER A OG  1 
ATOM   4316 N  N   . GLY A 1 547 ? 147.288 132.507 117.289 1.00 87.72  ? 547 GLY A N   1 
ATOM   4317 C  CA  . GLY A 1 547 ? 148.607 132.063 116.899 1.00 92.42  ? 547 GLY A CA  1 
ATOM   4318 C  C   . GLY A 1 547 ? 148.873 130.590 117.111 1.00 95.05  ? 547 GLY A C   1 
ATOM   4319 O  O   . GLY A 1 547 ? 149.945 130.111 116.725 1.00 95.35  ? 547 GLY A O   1 
ATOM   4320 N  N   . SER A 1 548 ? 147.941 129.860 117.712 1.00 97.28  ? 548 SER A N   1 
ATOM   4321 C  CA  . SER A 1 548 ? 148.106 128.428 117.893 1.00 96.18  ? 548 SER A CA  1 
ATOM   4322 C  C   . SER A 1 548 ? 147.937 127.697 116.564 1.00 103.00 ? 548 SER A C   1 
ATOM   4323 O  O   . SER A 1 548 ? 147.378 128.222 115.598 1.00 101.83 ? 548 SER A O   1 
ATOM   4324 C  CB  . SER A 1 548 ? 147.104 127.898 118.916 1.00 94.78  ? 548 SER A CB  1 
ATOM   4325 O  OG  . SER A 1 548 ? 145.905 127.488 118.284 1.00 105.69 ? 548 SER A OG  1 
ATOM   4326 N  N   . THR A 1 549 ? 148.445 126.516 116.405 1.00 100.05 ? 549 THR A N   1 
ATOM   4327 C  CA  . THR A 1 549 ? 148.224 125.707 115.191 1.00 96.17  ? 549 THR A CA  1 
ATOM   4328 C  C   . THR A 1 549 ? 146.801 125.163 115.057 1.00 96.22  ? 549 THR A C   1 
ATOM   4329 O  O   . THR A 1 549 ? 145.977 125.428 115.911 1.00 100.66 ? 549 THR A O   1 
ATOM   4330 C  CB  . THR A 1 549 ? 149.209 124.529 115.181 1.00 97.24  ? 549 THR A CB  1 
ATOM   4331 O  OG1 . THR A 1 549 ? 148.861 123.630 116.234 1.00 100.46 ? 549 THR A OG1 1 
ATOM   4332 C  CG2 . THR A 1 549 ? 150.652 124.958 115.310 1.00 99.24  ? 549 THR A CG2 1 
ATOM   4333 N  N   . SER A 1 550 ? 146.546 124.430 113.993 1.00 92.52  ? 550 SER A N   1 
ATOM   4334 C  CA  . SER A 1 550 ? 145.274 123.733 113.740 1.00 94.57  ? 550 SER A CA  1 
ATOM   4335 C  C   . SER A 1 550 ? 144.976 122.598 114.751 1.00 95.38  ? 550 SER A C   1 
ATOM   4336 O  O   . SER A 1 550 ? 143.829 122.188 114.751 1.00 93.26  ? 550 SER A O   1 
ATOM   4337 C  CB  . SER A 1 550 ? 145.314 123.260 112.293 1.00 91.43  ? 550 SER A CB  1 
ATOM   4338 O  OG  . SER A 1 550 ? 146.250 122.224 112.092 1.00 99.51  ? 550 SER A OG  1 
ATOM   4339 N  N   . ALA A 1 551 ? 145.922 122.119 115.617 1.00 94.12  ? 551 ALA A N   1 
ATOM   4340 C  CA  . ALA A 1 551 ? 145.529 121.065 116.548 1.00 91.63  ? 551 ALA A CA  1 
ATOM   4341 C  C   . ALA A 1 551 ? 144.604 121.588 117.641 1.00 92.87  ? 551 ALA A C   1 
ATOM   4342 O  O   . ALA A 1 551 ? 143.764 120.834 118.149 1.00 98.71  ? 551 ALA A O   1 
ATOM   4343 C  CB  . ALA A 1 551 ? 146.767 120.420 117.166 1.00 92.41  ? 551 ALA A CB  1 
ATOM   4344 N  N   . SER A 1 552 ? 144.673 122.889 117.949 1.00 93.38  ? 552 SER A N   1 
ATOM   4345 C  CA  . SER A 1 552 ? 143.818 123.551 118.967 1.00 98.15  ? 552 SER A CA  1 
ATOM   4346 C  C   . SER A 1 552 ? 142.387 123.509 118.517 1.00 100.62 ? 552 SER A C   1 
ATOM   4347 O  O   . SER A 1 552 ? 141.513 123.266 119.342 1.00 104.41 ? 552 SER A O   1 
ATOM   4348 C  CB  . SER A 1 552 ? 144.199 125.018 119.267 1.00 98.72  ? 552 SER A CB  1 
ATOM   4349 O  OG  . SER A 1 552 ? 143.392 125.966 118.590 1.00 102.16 ? 552 SER A OG  1 
ATOM   4350 N  N   . MET A 1 553 ? 142.092 123.811 117.252 1.00 101.96 ? 553 MET A N   1 
ATOM   4351 C  CA  . MET A 1 553 ? 140.680 123.716 116.817 1.00 101.65 ? 553 MET A CA  1 
ATOM   4352 C  C   . MET A 1 553 ? 140.203 122.299 117.050 1.00 100.35 ? 553 MET A C   1 
ATOM   4353 O  O   . MET A 1 553 ? 139.093 122.139 117.531 1.00 98.71  ? 553 MET A O   1 
ATOM   4354 C  CB  . MET A 1 553 ? 140.443 124.099 115.353 1.00 102.06 ? 553 MET A CB  1 
ATOM   4355 C  CG  . MET A 1 553 ? 140.415 125.602 115.123 1.00 102.83 ? 553 MET A CG  1 
ATOM   4356 S  SD  . MET A 1 553 ? 140.362 126.123 113.391 1.00 117.70 ? 553 MET A SD  1 
ATOM   4357 C  CE  . MET A 1 553 ? 141.640 125.103 112.672 1.00 102.96 ? 553 MET A CE  1 
ATOM   4358 N  N   . ALA A 1 554 ? 141.047 121.335 116.752 1.00 93.71  ? 554 ALA A N   1 
ATOM   4359 C  CA  . ALA A 1 554 ? 140.511 119.990 116.899 1.00 90.54  ? 554 ALA A CA  1 
ATOM   4360 C  C   . ALA A 1 554 ? 140.225 119.663 118.358 1.00 94.01  ? 554 ALA A C   1 
ATOM   4361 O  O   . ALA A 1 554 ? 139.110 119.252 118.706 1.00 96.18  ? 554 ALA A O   1 
ATOM   4362 C  CB  . ALA A 1 554 ? 141.490 118.974 116.316 1.00 93.01  ? 554 ALA A CB  1 
ATOM   4363 N  N   . ILE A 1 555 ? 141.233 119.745 119.218 1.00 100.54 ? 555 ILE A N   1 
ATOM   4364 C  CA  . ILE A 1 555 ? 141.097 119.391 120.646 1.00 96.69  ? 555 ILE A CA  1 
ATOM   4365 C  C   . ILE A 1 555 ? 140.005 120.213 121.316 1.00 99.23  ? 555 ILE A C   1 
ATOM   4366 O  O   . ILE A 1 555 ? 139.137 119.615 121.950 1.00 107.72 ? 555 ILE A O   1 
ATOM   4367 C  CB  . ILE A 1 555 ? 142.462 119.522 121.357 1.00 95.50  ? 555 ILE A CB  1 
ATOM   4368 C  CG1 . ILE A 1 555 ? 143.409 118.388 120.968 1.00 104.48 ? 555 ILE A CG1 1 
ATOM   4369 C  CG2 . ILE A 1 555 ? 142.269 119.620 122.864 1.00 96.71  ? 555 ILE A CG2 1 
ATOM   4370 C  CD1 . ILE A 1 555 ? 144.729 118.860 120.434 1.00 105.45 ? 555 ILE A CD1 1 
ATOM   4371 N  N   . GLY A 1 556 ? 140.087 121.517 121.249 1.00 84.36  ? 556 GLY A N   1 
ATOM   4372 C  CA  . GLY A 1 556 ? 139.110 122.325 121.959 1.00 83.51  ? 556 GLY A CA  1 
ATOM   4373 C  C   . GLY A 1 556 ? 137.692 122.053 121.503 1.00 86.73  ? 556 GLY A C   1 
ATOM   4374 O  O   . GLY A 1 556 ? 136.783 121.911 122.324 1.00 90.55  ? 556 GLY A O   1 
ATOM   4375 N  N   . ALA A 1 557 ? 137.488 121.953 120.189 1.00 99.54  ? 557 ALA A N   1 
ATOM   4376 C  CA  . ALA A 1 557 ? 136.152 121.685 119.667 1.00 100.27 ? 557 ALA A CA  1 
ATOM   4377 C  C   . ALA A 1 557 ? 135.645 120.320 120.106 1.00 103.03 ? 557 ALA A C   1 
ATOM   4378 O  O   . ALA A 1 557 ? 134.488 120.187 120.524 1.00 105.17 ? 557 ALA A O   1 
ATOM   4379 C  CB  . ALA A 1 557 ? 136.154 121.785 118.143 1.00 103.56 ? 557 ALA A CB  1 
ATOM   4380 N  N   . CYS A 1 558 ? 136.446 119.277 120.172 1.00 111.16 ? 558 CYS A N   1 
ATOM   4381 C  CA  . CYS A 1 558 ? 135.780 117.969 120.375 1.00 106.34 ? 558 CYS A CA  1 
ATOM   4382 C  C   . CYS A 1 558 ? 135.465 117.772 121.855 1.00 107.03 ? 558 CYS A C   1 
ATOM   4383 O  O   . CYS A 1 558 ? 134.391 117.275 122.169 1.00 107.64 ? 558 CYS A O   1 
ATOM   4384 C  CB  . CYS A 1 558 ? 136.626 116.852 119.804 1.00 108.82 ? 558 CYS A CB  1 
ATOM   4385 S  SG  . CYS A 1 558 ? 136.781 116.960 118.005 1.00 126.05 ? 558 CYS A SG  1 
ATOM   4386 N  N   . PHE A 1 559 ? 136.373 118.172 122.722 1.00 111.20 ? 559 PHE A N   1 
ATOM   4387 C  CA  . PHE A 1 559 ? 136.216 117.941 124.175 1.00 107.11 ? 559 PHE A CA  1 
ATOM   4388 C  C   . PHE A 1 559 ? 135.278 118.997 124.725 1.00 106.77 ? 559 PHE A C   1 
ATOM   4389 O  O   . PHE A 1 559 ? 134.460 118.688 125.579 1.00 104.48 ? 559 PHE A O   1 
ATOM   4390 C  CB  . PHE A 1 559 ? 137.545 118.039 124.919 1.00 104.34 ? 559 PHE A CB  1 
ATOM   4391 C  CG  . PHE A 1 559 ? 138.527 116.925 124.672 1.00 109.00 ? 559 PHE A CG  1 
ATOM   4392 C  CD1 . PHE A 1 559 ? 138.614 115.857 125.547 1.00 108.03 ? 559 PHE A CD1 1 
ATOM   4393 C  CD2 . PHE A 1 559 ? 139.393 116.966 123.596 1.00 113.72 ? 559 PHE A CD2 1 
ATOM   4394 C  CE1 . PHE A 1 559 ? 139.531 114.842 125.335 1.00 109.09 ? 559 PHE A CE1 1 
ATOM   4395 C  CE2 . PHE A 1 559 ? 140.309 115.952 123.386 1.00 113.87 ? 559 PHE A CE2 1 
ATOM   4396 C  CZ  . PHE A 1 559 ? 140.376 114.892 124.255 1.00 113.78 ? 559 PHE A CZ  1 
ATOM   4397 N  N   . SER A 1 560 ? 135.387 120.221 124.236 1.00 117.88 ? 560 SER A N   1 
ATOM   4398 C  CA  . SER A 1 560 ? 134.391 121.136 124.781 1.00 117.11 ? 560 SER A CA  1 
ATOM   4399 C  C   . SER A 1 560 ? 132.980 120.601 124.581 1.00 117.04 ? 560 SER A C   1 
ATOM   4400 O  O   . SER A 1 560 ? 132.105 120.823 125.427 1.00 112.59 ? 560 SER A O   1 
ATOM   4401 C  CB  . SER A 1 560 ? 134.534 122.514 124.136 1.00 117.52 ? 560 SER A CB  1 
ATOM   4402 O  OG  . SER A 1 560 ? 135.354 123.359 124.922 1.00 115.72 ? 560 SER A OG  1 
ATOM   4403 N  N   . ALA A 1 561 ? 132.739 119.898 123.472 1.00 126.78 ? 561 ALA A N   1 
ATOM   4404 C  CA  . ALA A 1 561 ? 131.452 119.245 123.265 1.00 126.09 ? 561 ALA A CA  1 
ATOM   4405 C  C   . ALA A 1 561 ? 131.195 118.148 124.287 1.00 128.87 ? 561 ALA A C   1 
ATOM   4406 O  O   . ALA A 1 561 ? 130.032 117.820 124.544 1.00 130.19 ? 561 ALA A O   1 
ATOM   4407 C  CB  . ALA A 1 561 ? 131.376 118.669 121.851 1.00 124.98 ? 561 ALA A CB  1 
ATOM   4408 N  N   . LEU A 1 562 ? 132.248 117.571 124.867 1.00 137.07 ? 562 LEU A N   1 
ATOM   4409 C  CA  . LEU A 1 562 ? 132.079 116.585 125.927 1.00 139.00 ? 562 LEU A CA  1 
ATOM   4410 C  C   . LEU A 1 562 ? 131.592 117.204 127.228 1.00 137.11 ? 562 LEU A C   1 
ATOM   4411 O  O   . LEU A 1 562 ? 131.171 116.469 128.126 1.00 130.64 ? 562 LEU A O   1 
ATOM   4412 C  CB  . LEU A 1 562 ? 133.395 115.843 126.168 1.00 137.23 ? 562 LEU A CB  1 
ATOM   4413 C  CG  . LEU A 1 562 ? 133.771 114.786 125.127 1.00 136.04 ? 562 LEU A CG  1 
ATOM   4414 C  CD1 . LEU A 1 562 ? 135.169 114.247 125.391 1.00 134.19 ? 562 LEU A CD1 1 
ATOM   4415 C  CD2 . LEU A 1 562 ? 132.753 113.657 125.115 1.00 134.83 ? 562 LEU A CD2 1 
ATOM   4416 N  N   . GLU A 1 563 ? 131.641 118.530 127.353 1.00 135.26 ? 563 GLU A N   1 
ATOM   4417 C  CA  . GLU A 1 563 ? 131.123 119.221 128.534 1.00 132.91 ? 563 GLU A CA  1 
ATOM   4418 C  C   . GLU A 1 563 ? 129.632 119.497 128.320 1.00 134.38 ? 563 GLU A C   1 
ATOM   4419 O  O   . GLU A 1 563 ? 129.163 120.634 128.243 1.00 134.04 ? 563 GLU A O   1 
ATOM   4420 C  CB  . GLU A 1 563 ? 131.924 120.492 128.800 1.00 133.74 ? 563 GLU A CB  1 
ATOM   4421 C  CG  . GLU A 1 563 ? 131.468 121.333 129.996 1.00 134.82 ? 563 GLU A CG  1 
ATOM   4422 C  CD  . GLU A 1 563 ? 131.756 120.684 131.338 1.00 136.27 ? 563 GLU A CD  1 
ATOM   4423 O  OE1 . GLU A 1 563 ? 132.337 119.580 131.370 1.00 134.19 ? 563 GLU A OE1 1 
ATOM   4424 O  OE2 . GLU A 1 563 ? 131.393 121.288 132.371 1.00 135.85 ? 563 GLU A OE2 1 
ATOM   4425 N  N   . VAL A 1 564 ? 128.887 118.403 128.181 1.00 143.11 ? 564 VAL A N   1 
ATOM   4426 C  CA  . VAL A 1 564 ? 127.435 118.454 128.063 1.00 143.86 ? 564 VAL A CA  1 
ATOM   4427 C  C   . VAL A 1 564 ? 126.856 117.455 129.054 1.00 144.08 ? 564 VAL A C   1 
ATOM   4428 O  O   . VAL A 1 564 ? 125.674 117.527 129.414 1.00 145.53 ? 564 VAL A O   1 
ATOM   4429 C  CB  . VAL A 1 564 ? 126.976 118.158 126.622 1.00 141.59 ? 564 VAL A CB  1 
ATOM   4430 C  CG1 . VAL A 1 564 ? 127.334 116.731 126.225 1.00 140.13 ? 564 VAL A CG1 1 
ATOM   4431 C  CG2 . VAL A 1 564 ? 125.483 118.415 126.462 1.00 140.18 ? 564 VAL A CG2 1 
ATOM   4432 N  N   . VAL A 1 565 ? 127.692 116.521 129.508 1.00 146.64 ? 565 VAL A N   1 
ATOM   4433 C  CA  . VAL A 1 565 ? 127.236 115.516 130.469 1.00 147.80 ? 565 VAL A CA  1 
ATOM   4434 C  C   . VAL A 1 565 ? 126.743 116.142 131.769 1.00 146.24 ? 565 VAL A C   1 
ATOM   4435 O  O   . VAL A 1 565 ? 125.632 115.810 132.204 1.00 146.62 ? 565 VAL A O   1 
ATOM   4436 C  CB  . VAL A 1 565 ? 128.331 114.461 130.691 1.00 148.50 ? 565 VAL A CB  1 
ATOM   4437 C  CG1 . VAL A 1 565 ? 127.769 113.258 131.431 1.00 146.66 ? 565 VAL A CG1 1 
ATOM   4438 C  CG2 . VAL A 1 565 ? 128.941 114.042 129.362 1.00 147.45 ? 565 VAL A CG2 1 
ATOM   4439 N  N   . PRO A 1 566 ? 127.487 117.047 132.452 1.00 139.36 ? 566 PRO A N   1 
ATOM   4440 C  CA  . PRO A 1 566 ? 127.041 117.558 133.758 1.00 140.54 ? 566 PRO A CA  1 
ATOM   4441 C  C   . PRO A 1 566 ? 125.839 118.505 133.651 1.00 144.04 ? 566 PRO A C   1 
ATOM   4442 O  O   . PRO A 1 566 ? 124.818 118.212 134.250 1.00 148.08 ? 566 PRO A O   1 
ATOM   4443 C  CB  . PRO A 1 566 ? 128.241 118.362 134.287 1.00 138.60 ? 566 PRO A CB  1 
ATOM   4444 C  CG  . PRO A 1 566 ? 129.400 117.973 133.396 1.00 139.87 ? 566 PRO A CG  1 
ATOM   4445 C  CD  . PRO A 1 566 ? 128.768 117.653 132.060 1.00 138.54 ? 566 PRO A CD  1 
ATOM   4446 N  N   . LEU A 1 567 ? 126.043 119.489 132.773 1.00 135.15 ? 567 LEU A N   1 
ATOM   4447 C  CA  . LEU A 1 567 ? 125.055 120.559 132.525 1.00 136.74 ? 567 LEU A CA  1 
ATOM   4448 C  C   . LEU A 1 567 ? 123.618 120.044 132.484 1.00 139.38 ? 567 LEU A C   1 
ATOM   4449 O  O   . LEU A 1 567 ? 122.735 120.706 133.038 1.00 139.93 ? 567 LEU A O   1 
ATOM   4450 C  CB  . LEU A 1 567 ? 125.468 121.080 131.151 1.00 133.26 ? 567 LEU A CB  1 
ATOM   4451 C  CG  . LEU A 1 567 ? 125.416 122.586 130.943 1.00 132.73 ? 567 LEU A CG  1 
ATOM   4452 C  CD1 . LEU A 1 567 ? 126.734 123.078 130.365 1.00 133.98 ? 567 LEU A CD1 1 
ATOM   4453 C  CD2 . LEU A 1 567 ? 124.264 122.929 130.019 1.00 131.63 ? 567 LEU A CD2 1 
ATOM   4454 N  N   . VAL A 1 568 ? 123.400 118.915 131.805 1.00 141.42 ? 568 VAL A N   1 
ATOM   4455 C  CA  . VAL A 1 568 ? 122.017 118.401 131.576 1.00 140.77 ? 568 VAL A CA  1 
ATOM   4456 C  C   . VAL A 1 568 ? 121.458 117.892 132.908 1.00 142.27 ? 568 VAL A C   1 
ATOM   4457 O  O   . VAL A 1 568 ? 120.538 118.536 133.450 1.00 139.45 ? 568 VAL A O   1 
ATOM   4458 C  CB  . VAL A 1 568 ? 121.995 117.299 130.501 1.00 137.22 ? 568 VAL A CB  1 
ATOM   4459 C  CG1 . VAL A 1 568 ? 120.599 116.719 130.322 1.00 138.48 ? 568 VAL A CG1 1 
ATOM   4460 C  CG2 . VAL A 1 568 ? 122.542 117.799 129.173 1.00 135.33 ? 568 VAL A CG2 1 
ATOM   4461 N  N   . LEU A 1 569 ? 122.118 116.751 133.442 1.00 140.02 ? 569 LEU A N   1 
ATOM   4462 C  CA  . LEU A 1 569 ? 121.508 116.157 134.660 1.00 137.53 ? 569 LEU A CA  1 
ATOM   4463 C  C   . LEU A 1 569 ? 121.420 117.222 135.760 1.00 136.01 ? 569 LEU A C   1 
ATOM   4464 O  O   . LEU A 1 569 ? 120.686 116.993 136.741 1.00 136.15 ? 569 LEU A O   1 
ATOM   4465 C  CB  . LEU A 1 569 ? 122.357 114.962 135.108 1.00 134.76 ? 569 LEU A CB  1 
ATOM   4466 C  CG  . LEU A 1 569 ? 123.647 114.735 134.324 1.00 134.22 ? 569 LEU A CG  1 
ATOM   4467 C  CD1 . LEU A 1 569 ? 124.823 115.438 134.986 1.00 134.45 ? 569 LEU A CD1 1 
ATOM   4468 C  CD2 . LEU A 1 569 ? 123.934 113.249 134.168 1.00 136.23 ? 569 LEU A CD2 1 
ATOM   4469 N  N   . LEU A 1 570 ? 122.139 118.338 135.596 1.00 133.34 ? 570 LEU A N   1 
ATOM   4470 C  CA  . LEU A 1 570 ? 122.178 119.372 136.648 1.00 135.34 ? 570 LEU A CA  1 
ATOM   4471 C  C   . LEU A 1 570 ? 120.736 119.709 137.002 1.00 134.95 ? 570 LEU A C   1 
ATOM   4472 O  O   . LEU A 1 570 ? 119.973 120.024 136.083 1.00 134.94 ? 570 LEU A O   1 
ATOM   4473 C  CB  . LEU A 1 570 ? 122.981 120.584 136.198 1.00 136.27 ? 570 LEU A CB  1 
ATOM   4474 C  CG  . LEU A 1 570 ? 124.072 120.992 137.186 1.00 141.41 ? 570 LEU A CG  1 
ATOM   4475 C  CD1 . LEU A 1 570 ? 125.292 120.095 137.065 1.00 136.27 ? 570 LEU A CD1 1 
ATOM   4476 C  CD2 . LEU A 1 570 ? 124.460 122.449 137.023 1.00 139.25 ? 570 LEU A CD2 1 
ATOM   4477 N  N   . GLY A 1 571 ? 120.389 119.517 138.278 1.00 30.00  ? 571 GLY A N   1 
ATOM   4478 C  CA  . GLY A 1 571 ? 119.156 120.047 138.876 1.00 30.00  ? 571 GLY A CA  1 
ATOM   4479 C  C   . GLY A 1 571 ? 117.946 119.209 138.530 1.00 30.00  ? 571 GLY A C   1 
ATOM   4480 O  O   . GLY A 1 571 ? 116.876 119.491 139.077 1.00 30.00  ? 571 GLY A O   1 
ATOM   4481 N  N   . ARG A 1 572 ? 118.072 118.282 137.578 1.00 157.85 ? 572 ARG A N   1 
ATOM   4482 C  CA  . ARG A 1 572 ? 116.939 117.362 137.369 1.00 159.20 ? 572 ARG A CA  1 
ATOM   4483 C  C   . ARG A 1 572 ? 116.592 116.936 138.781 1.00 163.07 ? 572 ARG A C   1 
ATOM   4484 O  O   . ARG A 1 572 ? 115.420 117.043 139.168 1.00 163.60 ? 572 ARG A O   1 
ATOM   4485 C  CB  . ARG A 1 572 ? 117.320 116.149 136.529 1.00 157.78 ? 572 ARG A CB  1 
ATOM   4486 C  CG  . ARG A 1 572 ? 116.692 116.115 135.143 1.00 159.50 ? 572 ARG A CG  1 
ATOM   4487 C  CD  . ARG A 1 572 ? 117.057 114.849 134.392 1.00 162.92 ? 572 ARG A CD  1 
ATOM   4488 N  NE  . ARG A 1 572 ? 116.320 114.695 133.143 1.00 164.88 ? 572 ARG A NE  1 
ATOM   4489 C  CZ  . ARG A 1 572 ? 116.455 113.675 132.300 1.00 163.69 ? 572 ARG A CZ  1 
ATOM   4490 N  NH1 . ARG A 1 572 ? 115.577 113.501 131.328 1.00 160.76 ? 572 ARG A NH1 1 
ATOM   4491 N  NH2 . ARG A 1 572 ? 117.463 112.831 132.431 1.00 162.71 ? 572 ARG A NH2 1 
ATOM   4492 N  N   . GLU A 1 573 ? 117.618 116.557 139.535 1.00 177.96 ? 573 GLU A N   1 
ATOM   4493 C  CA  . GLU A 1 573 ? 117.381 116.056 140.909 1.00 180.03 ? 573 GLU A CA  1 
ATOM   4494 C  C   . GLU A 1 573 ? 116.769 117.166 141.764 1.00 179.35 ? 573 GLU A C   1 
ATOM   4495 O  O   . GLU A 1 573 ? 116.345 116.871 142.895 1.00 175.56 ? 573 GLU A O   1 
ATOM   4496 C  CB  . GLU A 1 573 ? 118.662 115.500 141.531 1.00 178.26 ? 573 GLU A CB  1 
ATOM   4497 C  CG  . GLU A 1 573 ? 118.474 114.147 142.190 1.00 181.89 ? 573 GLU A CG  1 
ATOM   4498 C  CD  . GLU A 1 573 ? 117.062 113.587 142.140 1.00 181.84 ? 573 GLU A CD  1 
ATOM   4499 O  OE1 . GLU A 1 573 ? 116.784 112.765 141.248 1.00 182.48 ? 573 GLU A OE1 1 
ATOM   4500 O  OE2 . GLU A 1 573 ? 116.247 113.960 143.007 1.00 179.66 ? 573 GLU A OE2 1 
ATOM   4501 N  N   . ALA A 1 574 ? 116.720 118.402 141.253 1.00 176.40 ? 574 ALA A N   1 
ATOM   4502 C  CA  . ALA A 1 574 ? 116.019 119.367 142.126 1.00 175.10 ? 574 ALA A CA  1 
ATOM   4503 C  C   . ALA A 1 574 ? 114.526 119.295 141.800 1.00 174.85 ? 574 ALA A C   1 
ATOM   4504 O  O   . ALA A 1 574 ? 113.728 119.200 142.740 1.00 173.01 ? 574 ALA A O   1 
ATOM   4505 C  CB  . ALA A 1 574 ? 116.569 120.751 141.905 1.00 173.42 ? 574 ALA A CB  1 
ATOM   4506 N  N   . TYR A 1 575 ? 114.173 119.324 140.509 1.00 175.19 ? 575 TYR A N   1 
ATOM   4507 C  CA  . TYR A 1 575 ? 112.766 119.174 140.157 1.00 174.45 ? 575 TYR A CA  1 
ATOM   4508 C  C   . TYR A 1 575 ? 112.211 117.839 140.640 1.00 175.75 ? 575 TYR A C   1 
ATOM   4509 O  O   . TYR A 1 575 ? 111.007 117.722 140.897 1.00 177.35 ? 575 TYR A O   1 
ATOM   4510 C  CB  . TYR A 1 575 ? 112.583 119.325 138.646 1.00 172.71 ? 575 TYR A CB  1 
ATOM   4511 C  CG  . TYR A 1 575 ? 111.190 118.999 138.151 1.00 174.44 ? 575 TYR A CG  1 
ATOM   4512 C  CD1 . TYR A 1 575 ? 110.896 117.757 137.604 1.00 174.63 ? 575 TYR A CD1 1 
ATOM   4513 C  CD2 . TYR A 1 575 ? 110.169 119.936 138.235 1.00 174.04 ? 575 TYR A CD2 1 
ATOM   4514 C  CE1 . TYR A 1 575 ? 109.623 117.459 137.154 1.00 174.07 ? 575 TYR A CE1 1 
ATOM   4515 C  CE2 . TYR A 1 575 ? 108.894 119.647 137.788 1.00 173.90 ? 575 TYR A CE2 1 
ATOM   4516 C  CZ  . TYR A 1 575 ? 108.627 118.407 137.246 1.00 174.04 ? 575 TYR A CZ  1 
ATOM   4517 O  OH  . TYR A 1 575 ? 107.360 118.113 136.800 1.00 172.67 ? 575 TYR A OH  1 
ATOM   4518 N  N   . GLU A 1 576 ? 113.071 116.828 140.773 1.00 179.53 ? 576 GLU A N   1 
ATOM   4519 C  CA  . GLU A 1 576 ? 112.655 115.545 141.325 1.00 180.14 ? 576 GLU A CA  1 
ATOM   4520 C  C   . GLU A 1 576 ? 112.327 115.688 142.804 1.00 179.40 ? 576 GLU A C   1 
ATOM   4521 O  O   . GLU A 1 576 ? 111.682 114.815 143.394 1.00 176.45 ? 576 GLU A O   1 
ATOM   4522 C  CB  . GLU A 1 576 ? 113.743 114.487 141.125 1.00 179.68 ? 576 GLU A CB  1 
ATOM   4523 C  CG  . GLU A 1 576 ? 114.405 114.491 139.754 1.00 178.94 ? 576 GLU A CG  1 
ATOM   4524 C  CD  . GLU A 1 576 ? 113.409 114.570 138.615 1.00 178.71 ? 576 GLU A CD  1 
ATOM   4525 O  OE1 . GLU A 1 576 ? 113.111 115.693 138.158 1.00 177.53 ? 576 GLU A OE1 1 
ATOM   4526 O  OE2 . GLU A 1 576 ? 112.924 113.506 138.174 1.00 178.13 ? 576 GLU A OE2 1 
ATOM   4527 N  N   . HIS A 1 577 ? 112.770 116.790 143.411 1.00 181.66 ? 577 HIS A N   1 
ATOM   4528 C  CA  . HIS A 1 577 ? 112.509 117.046 144.821 1.00 181.62 ? 577 HIS A CA  1 
ATOM   4529 C  C   . HIS A 1 577 ? 111.897 118.410 145.099 1.00 181.07 ? 577 HIS A C   1 
ATOM   4530 O  O   . HIS A 1 577 ? 111.681 118.727 146.272 1.00 180.93 ? 577 HIS A O   1 
ATOM   4531 C  CB  . HIS A 1 577 ? 113.805 116.907 145.633 1.00 181.39 ? 577 HIS A CB  1 
ATOM   4532 C  CG  . HIS A 1 577 ? 114.118 115.500 146.036 1.00 181.75 ? 577 HIS A CG  1 
ATOM   4533 N  ND1 . HIS A 1 577 ? 113.175 114.495 146.022 1.00 180.70 ? 577 HIS A ND1 1 
ATOM   4534 C  CD2 . HIS A 1 577 ? 115.271 114.928 146.456 1.00 179.62 ? 577 HIS A CD2 1 
ATOM   4535 C  CE1 . HIS A 1 577 ? 113.733 113.365 146.421 1.00 178.39 ? 577 HIS A CE1 1 
ATOM   4536 N  NE2 . HIS A 1 577 ? 115.004 113.600 146.689 1.00 177.33 ? 577 HIS A NE2 1 
ATOM   4537 N  N   . TRP A 1 578 ? 111.623 119.228 144.082 1.00 178.53 ? 578 TRP A N   1 
ATOM   4538 C  CA  . TRP A 1 578 ? 111.038 120.548 144.291 1.00 178.02 ? 578 TRP A CA  1 
ATOM   4539 C  C   . TRP A 1 578 ? 109.656 120.417 144.915 1.00 178.95 ? 578 TRP A C   1 
ATOM   4540 O  O   . TRP A 1 578 ? 109.371 121.045 145.941 1.00 177.96 ? 578 TRP A O   1 
ATOM   4541 C  CB  . TRP A 1 578 ? 110.966 121.318 142.968 1.00 178.58 ? 578 TRP A CB  1 
ATOM   4542 C  CG  . TRP A 1 578 ? 111.039 122.810 143.126 1.00 179.24 ? 578 TRP A CG  1 
ATOM   4543 C  CD1 . TRP A 1 578 ? 112.091 123.615 142.803 1.00 178.45 ? 578 TRP A CD1 1 
ATOM   4544 C  CD2 . TRP A 1 578 ? 110.013 123.679 143.630 1.00 179.51 ? 578 TRP A CD2 1 
ATOM   4545 N  NE1 . TRP A 1 578 ? 111.792 124.926 143.082 1.00 179.33 ? 578 TRP A NE1 1 
ATOM   4546 C  CE2 . TRP A 1 578 ? 110.521 124.992 143.589 1.00 179.15 ? 578 TRP A CE2 1 
ATOM   4547 C  CE3 . TRP A 1 578 ? 108.717 123.474 144.112 1.00 177.72 ? 578 TRP A CE3 1 
ATOM   4548 C  CZ2 . TRP A 1 578 ? 109.779 126.094 144.012 1.00 176.81 ? 578 TRP A CZ2 1 
ATOM   4549 C  CZ3 . TRP A 1 578 ? 107.982 124.567 144.533 1.00 176.61 ? 578 TRP A CZ3 1 
ATOM   4550 C  CH2 . TRP A 1 578 ? 108.515 125.861 144.480 1.00 175.51 ? 578 TRP A CH2 1 
ATOM   4551 N  N   . SER A 1 579 ? 108.797 119.600 144.311 1.00 188.82 ? 579 SER A N   1 
ATOM   4552 C  CA  . SER A 1 579 ? 107.489 119.317 144.889 1.00 189.43 ? 579 SER A CA  1 
ATOM   4553 C  C   . SER A 1 579 ? 107.647 118.530 146.181 1.00 188.58 ? 579 SER A C   1 
ATOM   4554 O  O   . SER A 1 579 ? 107.971 117.340 146.164 1.00 187.72 ? 579 SER A O   1 
ATOM   4555 C  CB  . SER A 1 579 ? 106.634 118.532 143.892 1.00 188.56 ? 579 SER A CB  1 
ATOM   4556 O  OG  . SER A 1 579 ? 107.391 117.518 143.255 1.00 188.87 ? 579 SER A OG  1 
ATOM   4557 N  N   . TYR A 1 580 ? 107.414 119.205 147.306 1.00 185.04 ? 580 TYR A N   1 
ATOM   4558 C  CA  . TYR A 1 580 ? 107.693 118.614 148.607 1.00 184.03 ? 580 TYR A CA  1 
ATOM   4559 C  C   . TYR A 1 580 ? 106.485 118.496 149.524 1.00 186.20 ? 580 TYR A C   1 
ATOM   4560 O  O   . TYR A 1 580 ? 106.524 117.667 150.437 1.00 187.63 ? 580 TYR A O   1 
ATOM   4561 C  CB  . TYR A 1 580 ? 108.781 119.422 149.329 1.00 182.29 ? 580 TYR A CB  1 
ATOM   4562 N  N   . GLN A 1 581 ? 105.423 119.272 149.318 1.00 194.32 ? 581 GLN A N   1 
ATOM   4563 C  CA  . GLN A 1 581 ? 104.236 119.253 150.172 1.00 195.24 ? 581 GLN A CA  1 
ATOM   4564 C  C   . GLN A 1 581 ? 104.616 119.498 151.633 1.00 195.62 ? 581 GLN A C   1 
ATOM   4565 O  O   . GLN A 1 581 ? 104.340 118.693 152.526 1.00 195.11 ? 581 GLN A O   1 
ATOM   4566 C  CB  . GLN A 1 581 ? 103.465 117.940 150.010 1.00 193.77 ? 581 GLN A CB  1 
ATOM   4567 N  N   . HIS A 1 582 ? 105.267 120.642 151.856 1.00 191.91 ? 582 HIS A N   1 
ATOM   4568 C  CA  . HIS A 1 582 ? 105.712 121.064 153.184 1.00 191.88 ? 582 HIS A CA  1 
ATOM   4569 C  C   . HIS A 1 582 ? 106.652 120.039 153.817 1.00 191.79 ? 582 HIS A C   1 
ATOM   4570 O  O   . HIS A 1 582 ? 106.584 119.765 155.017 1.00 189.88 ? 582 HIS A O   1 
ATOM   4571 C  CB  . HIS A 1 582 ? 104.521 121.351 154.104 1.00 189.53 ? 582 HIS A CB  1 
ATOM   4572 N  N   . LEU A 1 583 ? 107.539 119.468 153.005 1.00 187.93 ? 583 LEU A N   1 
ATOM   4573 C  CA  . LEU A 1 583 ? 108.582 118.581 153.503 1.00 187.72 ? 583 LEU A CA  1 
ATOM   4574 C  C   . LEU A 1 583 ? 109.751 119.342 154.113 1.00 185.02 ? 583 LEU A C   1 
ATOM   4575 O  O   . LEU A 1 583 ? 110.616 118.722 154.739 1.00 182.99 ? 583 LEU A O   1 
ATOM   4576 C  CB  . LEU A 1 583 ? 109.091 117.672 152.380 1.00 186.70 ? 583 LEU A CB  1 
ATOM   4577 C  CG  . LEU A 1 583 ? 108.724 116.190 152.465 1.00 184.77 ? 583 LEU A CG  1 
ATOM   4578 C  CD1 . LEU A 1 583 ? 109.124 115.469 151.187 1.00 181.80 ? 583 LEU A CD1 1 
ATOM   4579 C  CD2 . LEU A 1 583 ? 109.377 115.546 153.676 1.00 183.55 ? 583 LEU A CD2 1 
ATOM   4580 N  N   . SER A 1 584 ? 109.798 120.664 153.946 1.00 168.29 ? 584 SER A N   1 
ATOM   4581 C  CA  . SER A 1 584 ? 110.855 121.487 154.524 1.00 167.17 ? 584 SER A CA  1 
ATOM   4582 C  C   . SER A 1 584 ? 110.465 121.829 155.958 1.00 170.10 ? 584 SER A C   1 
ATOM   4583 O  O   . SER A 1 584 ? 109.908 122.887 156.257 1.00 170.37 ? 584 SER A O   1 
ATOM   4584 C  CB  . SER A 1 584 ? 111.083 122.736 153.682 1.00 165.51 ? 584 SER A CB  1 
ATOM   4585 O  OG  . SER A 1 584 ? 111.472 122.396 152.364 1.00 164.34 ? 584 SER A OG  1 
ATOM   4586 N  N   . GLU A 1 585 ? 110.762 120.893 156.865 1.00 173.17 ? 585 GLU A N   1 
ATOM   4587 C  CA  . GLU A 1 585 ? 110.432 121.094 158.272 1.00 172.23 ? 585 GLU A CA  1 
ATOM   4588 C  C   . GLU A 1 585 ? 111.182 122.284 158.852 1.00 172.20 ? 585 GLU A C   1 
ATOM   4589 O  O   . GLU A 1 585 ? 110.607 123.092 159.592 1.00 169.54 ? 585 GLU A O   1 
ATOM   4590 C  CB  . GLU A 1 585 ? 110.742 119.825 159.068 1.00 172.44 ? 585 GLU A CB  1 
ATOM   4591 C  CG  . GLU A 1 585 ? 110.312 118.540 158.382 1.00 173.55 ? 585 GLU A CG  1 
ATOM   4592 C  CD  . GLU A 1 585 ? 108.845 118.545 158.004 1.00 173.76 ? 585 GLU A CD  1 
ATOM   4593 O  OE1 . GLU A 1 585 ? 107.999 118.700 158.910 1.00 172.71 ? 585 GLU A OE1 1 
ATOM   4594 O  OE2 . GLU A 1 585 ? 108.537 118.393 156.804 1.00 174.06 ? 585 GLU A OE2 1 
ATOM   4595 N  N   . TRP A 1 586 ? 112.468 122.412 158.529 1.00 168.55 ? 586 TRP A N   1 
ATOM   4596 C  CA  . TRP A 1 586 ? 113.298 123.510 159.010 1.00 168.23 ? 586 TRP A CA  1 
ATOM   4597 C  C   . TRP A 1 586 ? 114.096 124.109 157.861 1.00 166.75 ? 586 TRP A C   1 
ATOM   4598 O  O   . TRP A 1 586 ? 115.159 124.706 158.064 1.00 168.19 ? 586 TRP A O   1 
ATOM   4599 C  CB  . TRP A 1 586 ? 114.234 123.050 160.126 1.00 166.18 ? 586 TRP A CB  1 
ATOM   4600 C  CG  . TRP A 1 586 ? 115.181 121.969 159.701 1.00 166.94 ? 586 TRP A CG  1 
ATOM   4601 C  CD1 . TRP A 1 586 ? 114.868 120.674 159.403 1.00 167.23 ? 586 TRP A CD1 1 
ATOM   4602 C  CD2 . TRP A 1 586 ? 116.594 122.096 159.504 1.00 166.68 ? 586 TRP A CD2 1 
ATOM   4603 N  NE1 . TRP A 1 586 ? 116.000 119.983 159.046 1.00 166.46 ? 586 TRP A NE1 1 
ATOM   4604 C  CE2 . TRP A 1 586 ? 117.073 120.834 159.098 1.00 167.84 ? 586 TRP A CE2 1 
ATOM   4605 C  CE3 . TRP A 1 586 ? 117.501 123.152 159.636 1.00 165.08 ? 586 TRP A CE3 1 
ATOM   4606 C  CZ2 . TRP A 1 586 ? 118.419 120.601 158.822 1.00 168.38 ? 586 TRP A CZ2 1 
ATOM   4607 C  CZ3 . TRP A 1 586 ? 118.835 122.917 159.361 1.00 166.67 ? 586 TRP A CZ3 1 
ATOM   4608 C  CH2 . TRP A 1 586 ? 119.281 121.652 158.959 1.00 168.40 ? 586 TRP A CH2 1 
ATOM   4609 N  N   . ALA A 1 587 ? 113.593 123.956 156.638 1.00 152.31 ? 587 ALA A N   1 
ATOM   4610 C  CA  . ALA A 1 587 ? 114.278 124.461 155.456 1.00 151.17 ? 587 ALA A CA  1 
ATOM   4611 C  C   . ALA A 1 587 ? 113.502 125.517 154.688 1.00 153.73 ? 587 ALA A C   1 
ATOM   4612 O  O   . ALA A 1 587 ? 114.106 126.210 153.860 1.00 157.81 ? 587 ALA A O   1 
ATOM   4613 C  CB  . ALA A 1 587 ? 114.618 123.310 154.497 1.00 150.98 ? 587 ALA A CB  1 
ATOM   4614 N  N   . LYS A 1 588 ? 112.196 125.669 154.921 1.00 162.65 ? 588 LYS A N   1 
ATOM   4615 C  CA  . LYS A 1 588 ? 111.441 126.698 154.218 1.00 166.09 ? 588 LYS A CA  1 
ATOM   4616 C  C   . LYS A 1 588 ? 111.776 128.096 154.721 1.00 166.19 ? 588 LYS A C   1 
ATOM   4617 O  O   . LYS A 1 588 ? 111.576 129.071 153.989 1.00 165.48 ? 588 LYS A O   1 
ATOM   4618 C  CB  . LYS A 1 588 ? 109.939 126.431 154.348 1.00 164.22 ? 588 LYS A CB  1 
ATOM   4619 C  CG  . LYS A 1 588 ? 109.084 127.206 153.357 1.00 165.27 ? 588 LYS A CG  1 
ATOM   4620 C  CD  . LYS A 1 588 ? 107.633 126.758 153.400 1.00 164.19 ? 588 LYS A CD  1 
ATOM   4621 C  CE  . LYS A 1 588 ? 106.800 127.495 152.364 1.00 162.51 ? 588 LYS A CE  1 
ATOM   4622 N  NZ  . LYS A 1 588 ? 105.375 127.063 152.378 1.00 162.88 ? 588 LYS A NZ  1 
ATOM   4623 N  N   . ARG A 1 589 ? 112.284 128.215 155.949 1.00 164.33 ? 589 ARG A N   1 
ATOM   4624 C  CA  . ARG A 1 589 ? 112.722 129.515 156.447 1.00 164.87 ? 589 ARG A CA  1 
ATOM   4625 C  C   . ARG A 1 589 ? 113.979 129.983 155.722 1.00 163.71 ? 589 ARG A C   1 
ATOM   4626 O  O   . ARG A 1 589 ? 114.175 131.186 155.510 1.00 161.72 ? 589 ARG A O   1 
ATOM   4627 C  CB  . ARG A 1 589 ? 112.950 129.443 157.959 1.00 165.50 ? 589 ARG A CB  1 
ATOM   4628 C  CG  . ARG A 1 589 ? 113.874 128.321 158.411 1.00 162.43 ? 589 ARG A CG  1 
ATOM   4629 C  CD  . ARG A 1 589 ? 115.305 128.805 158.601 1.00 163.23 ? 589 ARG A CD  1 
ATOM   4630 N  NE  . ARG A 1 589 ? 115.444 129.637 159.792 1.00 163.84 ? 589 ARG A NE  1 
ATOM   4631 C  CZ  . ARG A 1 589 ? 115.401 129.184 161.036 1.00 163.17 ? 589 ARG A CZ  1 
ATOM   4632 N  NH1 . ARG A 1 589 ? 115.245 127.898 161.299 1.00 162.87 ? 589 ARG A NH1 1 
ATOM   4633 N  NH2 . ARG A 1 589 ? 115.525 130.043 162.042 1.00 162.48 ? 589 ARG A NH2 1 
ATOM   4634 N  N   . LEU A 1 590 ? 114.841 129.044 155.340 1.00 149.42 ? 590 LEU A N   1 
ATOM   4635 C  CA  . LEU A 1 590 ? 116.040 129.324 154.554 1.00 145.26 ? 590 LEU A CA  1 
ATOM   4636 C  C   . LEU A 1 590 ? 115.837 129.022 153.074 1.00 147.67 ? 590 LEU A C   1 
ATOM   4637 O  O   . LEU A 1 590 ? 116.767 128.635 152.362 1.00 145.38 ? 590 LEU A O   1 
ATOM   4638 C  CB  . LEU A 1 590 ? 117.235 128.565 155.138 1.00 144.46 ? 590 LEU A CB  1 
ATOM   4639 C  CG  . LEU A 1 590 ? 117.375 127.036 155.280 1.00 147.09 ? 590 LEU A CG  1 
ATOM   4640 C  CD1 . LEU A 1 590 ? 117.339 126.219 153.991 1.00 142.43 ? 590 LEU A CD1 1 
ATOM   4641 C  CD2 . LEU A 1 590 ? 118.647 126.714 156.064 1.00 147.49 ? 590 LEU A CD2 1 
ATOM   4642 N  N   . ARG A 1 591 ? 114.619 129.246 152.573 1.00 145.27 ? 591 ARG A N   1 
ATOM   4643 C  CA  . ARG A 1 591 ? 114.289 128.899 151.194 1.00 141.39 ? 591 ARG A CA  1 
ATOM   4644 C  C   . ARG A 1 591 ? 115.134 129.678 150.192 1.00 136.57 ? 591 ARG A C   1 
ATOM   4645 O  O   . ARG A 1 591 ? 115.326 129.239 149.056 1.00 135.75 ? 591 ARG A O   1 
ATOM   4646 C  CB  . ARG A 1 591 ? 112.801 129.151 150.937 1.00 139.21 ? 591 ARG A CB  1 
ATOM   4647 C  CG  . ARG A 1 591 ? 112.434 130.624 150.834 1.00 138.80 ? 591 ARG A CG  1 
ATOM   4648 C  CD  . ARG A 1 591 ? 110.928 130.833 150.868 1.00 140.06 ? 591 ARG A CD  1 
ATOM   4649 N  NE  . ARG A 1 591 ? 110.390 131.177 149.558 1.00 142.93 ? 591 ARG A NE  1 
ATOM   4650 C  CZ  . ARG A 1 591 ? 109.438 132.077 149.354 1.00 142.84 ? 591 ARG A CZ  1 
ATOM   4651 N  NH1 . ARG A 1 591 ? 108.901 132.753 150.357 1.00 139.91 ? 591 ARG A NH1 1 
ATOM   4652 N  NH2 . ARG A 1 591 ? 109.015 132.305 148.114 1.00 142.80 ? 591 ARG A NH2 1 
ATOM   4653 N  N   . TRP A 1 592 ? 115.646 130.836 150.593 1.00 123.99 ? 592 TRP A N   1 
ATOM   4654 C  CA  . TRP A 1 592 ? 116.296 131.738 149.650 1.00 128.02 ? 592 TRP A CA  1 
ATOM   4655 C  C   . TRP A 1 592 ? 117.706 131.285 149.274 1.00 132.14 ? 592 TRP A C   1 
ATOM   4656 O  O   . TRP A 1 592 ? 118.013 131.179 148.072 1.00 129.84 ? 592 TRP A O   1 
ATOM   4657 C  CB  . TRP A 1 592 ? 116.297 133.161 150.214 1.00 126.73 ? 592 TRP A CB  1 
ATOM   4658 C  CG  . TRP A 1 592 ? 114.924 133.661 150.445 1.00 129.28 ? 592 TRP A CG  1 
ATOM   4659 C  CD1 . TRP A 1 592 ? 114.347 133.954 151.642 1.00 126.51 ? 592 TRP A CD1 1 
ATOM   4660 C  CD2 . TRP A 1 592 ? 113.940 133.930 149.442 1.00 132.24 ? 592 TRP A CD2 1 
ATOM   4661 N  NE1 . TRP A 1 592 ? 113.058 134.389 151.449 1.00 129.63 ? 592 TRP A NE1 1 
ATOM   4662 C  CE2 . TRP A 1 592 ? 112.785 134.385 150.105 1.00 131.99 ? 592 TRP A CE2 1 
ATOM   4663 C  CE3 . TRP A 1 592 ? 113.927 133.833 148.046 1.00 127.77 ? 592 TRP A CE3 1 
ATOM   4664 C  CZ2 . TRP A 1 592 ? 111.628 134.740 149.421 1.00 128.62 ? 592 TRP A CZ2 1 
ATOM   4665 C  CZ3 . TRP A 1 592 ? 112.782 134.182 147.371 1.00 126.44 ? 592 TRP A CZ3 1 
ATOM   4666 C  CH2 . TRP A 1 592 ? 111.646 134.627 148.054 1.00 126.99 ? 592 TRP A CH2 1 
ATOM   4667 N  N   . PRO A 1 593 ? 118.598 131.016 150.237 1.00 137.06 ? 593 PRO A N   1 
ATOM   4668 C  CA  . PRO A 1 593 ? 119.913 130.474 149.871 1.00 130.39 ? 593 PRO A CA  1 
ATOM   4669 C  C   . PRO A 1 593 ? 119.837 129.143 149.154 1.00 129.20 ? 593 PRO A C   1 
ATOM   4670 O  O   . PRO A 1 593 ? 120.743 128.822 148.379 1.00 126.51 ? 593 PRO A O   1 
ATOM   4671 C  CB  . PRO A 1 593 ? 120.609 130.336 151.235 1.00 126.41 ? 593 PRO A CB  1 
ATOM   4672 C  CG  . PRO A 1 593 ? 119.971 131.423 152.037 1.00 127.95 ? 593 PRO A CG  1 
ATOM   4673 C  CD  . PRO A 1 593 ? 118.534 131.207 151.698 1.00 133.10 ? 593 PRO A CD  1 
ATOM   4674 N  N   . LEU A 1 594 ? 118.768 128.380 149.364 1.00 126.55 ? 594 LEU A N   1 
ATOM   4675 C  CA  . LEU A 1 594 ? 118.628 127.067 148.771 1.00 122.27 ? 594 LEU A CA  1 
ATOM   4676 C  C   . LEU A 1 594 ? 117.975 127.137 147.398 1.00 126.66 ? 594 LEU A C   1 
ATOM   4677 O  O   . LEU A 1 594 ? 118.228 126.262 146.565 1.00 132.54 ? 594 LEU A O   1 
ATOM   4678 C  CB  . LEU A 1 594 ? 117.822 126.159 149.721 1.00 122.50 ? 594 LEU A CB  1 
ATOM   4679 C  CG  . LEU A 1 594 ? 117.459 124.685 149.527 1.00 126.30 ? 594 LEU A CG  1 
ATOM   4680 C  CD1 . LEU A 1 594 ? 116.572 124.428 148.332 1.00 129.75 ? 594 LEU A CD1 1 
ATOM   4681 C  CD2 . LEU A 1 594 ? 118.724 123.853 149.443 1.00 128.09 ? 594 LEU A CD2 1 
ATOM   4682 N  N   . MET A 1 595 ? 117.414 128.345 147.083 1.00 123.39 ? 595 MET A N   1 
ATOM   4683 C  CA  . MET A 1 595 ? 116.783 128.653 145.753 1.00 123.07 ? 595 MET A CA  1 
ATOM   4684 C  C   . MET A 1 595 ? 117.753 129.398 144.824 1.00 117.23 ? 595 MET A C   1 
ATOM   4685 O  O   . MET A 1 595 ? 117.486 129.445 143.633 1.00 112.81 ? 595 MET A O   1 
ATOM   4686 C  CB  . MET A 1 595 ? 115.488 129.481 145.852 1.00 122.40 ? 595 MET A CB  1 
ATOM   4687 C  CG  . MET A 1 595 ? 114.278 128.695 145.369 1.00 118.14 ? 595 MET A CG  1 
ATOM   4688 S  SD  . MET A 1 595 ? 112.918 129.635 144.626 1.00 127.57 ? 595 MET A SD  1 
ATOM   4689 C  CE  . MET A 1 595 ? 113.120 131.220 145.433 1.00 117.58 ? 595 MET A CE  1 
ATOM   4690 N  N   . CYS A 1 596 ? 118.787 130.020 145.389 1.00 111.81 ? 596 CYS A N   1 
ATOM   4691 C  CA  . CYS A 1 596 ? 119.872 130.571 144.567 1.00 110.44 ? 596 CYS A CA  1 
ATOM   4692 C  C   . CYS A 1 596 ? 120.439 129.389 143.802 1.00 110.88 ? 596 CYS A C   1 
ATOM   4693 O  O   . CYS A 1 596 ? 121.120 129.655 142.823 1.00 117.18 ? 596 CYS A O   1 
ATOM   4694 C  CB  . CYS A 1 596 ? 121.031 131.060 145.421 1.00 112.71 ? 596 CYS A CB  1 
ATOM   4695 S  SG  . CYS A 1 596 ? 120.899 132.762 146.047 1.00 130.14 ? 596 CYS A SG  1 
ATOM   4696 N  N   . PHE A 1 597 ? 120.192 128.147 144.252 1.00 107.36 ? 597 PHE A N   1 
ATOM   4697 C  CA  . PHE A 1 597 ? 120.832 127.017 143.599 1.00 106.43 ? 597 PHE A CA  1 
ATOM   4698 C  C   . PHE A 1 597 ? 119.971 126.406 142.492 1.00 103.95 ? 597 PHE A C   1 
ATOM   4699 O  O   . PHE A 1 597 ? 120.456 125.554 141.741 1.00 109.36 ? 597 PHE A O   1 
ATOM   4700 C  CB  . PHE A 1 597 ? 121.193 125.960 144.643 1.00 112.13 ? 597 PHE A CB  1 
ATOM   4701 C  CG  . PHE A 1 597 ? 122.069 126.481 145.749 1.00 117.15 ? 597 PHE A CG  1 
ATOM   4702 C  CD1 . PHE A 1 597 ? 123.064 127.408 145.485 1.00 114.60 ? 597 PHE A CD1 1 
ATOM   4703 C  CD2 . PHE A 1 597 ? 121.881 126.062 147.053 1.00 117.00 ? 597 PHE A CD2 1 
ATOM   4704 C  CE1 . PHE A 1 597 ? 123.868 127.894 146.503 1.00 111.02 ? 597 PHE A CE1 1 
ATOM   4705 C  CE2 . PHE A 1 597 ? 122.682 126.543 148.075 1.00 114.77 ? 597 PHE A CE2 1 
ATOM   4706 C  CZ  . PHE A 1 597 ? 123.674 127.461 147.798 1.00 110.51 ? 597 PHE A CZ  1 
ATOM   4707 N  N   . VAL A 1 598 ? 118.710 126.814 142.381 1.00 86.48  ? 598 VAL A N   1 
ATOM   4708 C  CA  . VAL A 1 598 ? 117.846 126.442 141.265 1.00 91.04  ? 598 VAL A CA  1 
ATOM   4709 C  C   . VAL A 1 598 ? 118.048 127.381 140.084 1.00 93.13  ? 598 VAL A C   1 
ATOM   4710 O  O   . VAL A 1 598 ? 118.122 126.945 138.931 1.00 95.91  ? 598 VAL A O   1 
ATOM   4711 C  CB  . VAL A 1 598 ? 116.365 126.410 141.701 1.00 90.75  ? 598 VAL A CB  1 
ATOM   4712 C  CG1 . VAL A 1 598 ? 115.484 125.924 140.564 1.00 91.29  ? 598 VAL A CG1 1 
ATOM   4713 C  CG2 . VAL A 1 598 ? 116.195 125.532 142.929 1.00 95.11  ? 598 VAL A CG2 1 
ATOM   4714 N  N   . ALA A 1 599 ? 118.143 128.683 140.357 1.00 89.71  ? 599 ALA A N   1 
ATOM   4715 C  CA  . ALA A 1 599 ? 118.562 129.624 139.328 1.00 85.68  ? 599 ALA A CA  1 
ATOM   4716 C  C   . ALA A 1 599 ? 119.961 129.296 138.828 1.00 86.82  ? 599 ALA A C   1 
ATOM   4717 O  O   . ALA A 1 599 ? 120.259 129.499 137.647 1.00 91.63  ? 599 ALA A O   1 
ATOM   4718 C  CB  . ALA A 1 599 ? 118.512 131.052 139.866 1.00 80.22  ? 599 ALA A CB  1 
ATOM   4719 N  N   . VAL A 1 600 ? 120.825 128.786 139.710 1.00 81.15  ? 600 VAL A N   1 
ATOM   4720 C  CA  . VAL A 1 600 ? 122.149 128.347 139.277 1.00 81.00  ? 600 VAL A CA  1 
ATOM   4721 C  C   . VAL A 1 600 ? 122.028 127.285 138.189 1.00 88.00  ? 600 VAL A C   1 
ATOM   4722 O  O   . VAL A 1 600 ? 122.683 127.366 137.144 1.00 98.84  ? 600 VAL A O   1 
ATOM   4723 C  CB  . VAL A 1 600 ? 122.966 127.829 140.475 1.00 76.02  ? 600 VAL A CB  1 
ATOM   4724 C  CG1 . VAL A 1 600 ? 124.149 127.004 139.994 1.00 73.31  ? 600 VAL A CG1 1 
ATOM   4725 C  CG2 . VAL A 1 600 ? 123.442 128.980 141.331 1.00 83.58  ? 600 VAL A CG2 1 
ATOM   4726 N  N   . ALA A 1 601 ? 121.182 126.277 138.415 1.00 91.59  ? 601 ALA A N   1 
ATOM   4727 C  CA  . ALA A 1 601 ? 121.016 125.211 137.431 1.00 90.45  ? 601 ALA A CA  1 
ATOM   4728 C  C   . ALA A 1 601 ? 120.372 125.729 136.150 1.00 93.10  ? 601 ALA A C   1 
ATOM   4729 O  O   . ALA A 1 601 ? 120.767 125.337 135.044 1.00 98.74  ? 601 ALA A O   1 
ATOM   4730 C  CB  . ALA A 1 601 ? 120.186 124.073 138.024 1.00 84.96  ? 601 ALA A CB  1 
ATOM   4731 N  N   . PHE A 1 602 ? 119.380 126.611 136.279 1.00 86.10  ? 602 PHE A N   1 
ATOM   4732 C  CA  . PHE A 1 602 ? 118.732 127.168 135.095 1.00 81.45  ? 602 PHE A CA  1 
ATOM   4733 C  C   . PHE A 1 602 ? 119.732 127.923 134.227 1.00 85.08  ? 602 PHE A C   1 
ATOM   4734 O  O   . PHE A 1 602 ? 119.759 127.761 133.000 1.00 94.35  ? 602 PHE A O   1 
ATOM   4735 C  CB  . PHE A 1 602 ? 117.583 128.089 135.510 1.00 83.43  ? 602 PHE A CB  1 
ATOM   4736 C  CG  . PHE A 1 602 ? 116.976 128.852 134.368 1.00 87.74  ? 602 PHE A CG  1 
ATOM   4737 C  CD1 . PHE A 1 602 ? 116.025 128.261 133.555 1.00 91.71  ? 602 PHE A CD1 1 
ATOM   4738 C  CD2 . PHE A 1 602 ? 117.362 130.155 134.102 1.00 85.82  ? 602 PHE A CD2 1 
ATOM   4739 C  CE1 . PHE A 1 602 ? 115.466 128.958 132.504 1.00 94.26  ? 602 PHE A CE1 1 
ATOM   4740 C  CE2 . PHE A 1 602 ? 116.809 130.853 133.051 1.00 84.45  ? 602 PHE A CE2 1 
ATOM   4741 C  CZ  . PHE A 1 602 ? 115.858 130.254 132.253 1.00 88.61  ? 602 PHE A CZ  1 
ATOM   4742 N  N   . TRP A 1 603 ? 120.567 128.753 134.849 1.00 76.36  ? 603 TRP A N   1 
ATOM   4743 C  CA  . TRP A 1 603 ? 121.516 129.548 134.077 1.00 75.84  ? 603 TRP A CA  1 
ATOM   4744 C  C   . TRP A 1 603 ? 122.682 128.702 133.589 1.00 82.36  ? 603 TRP A C   1 
ATOM   4745 O  O   . TRP A 1 603 ? 123.297 129.020 132.568 1.00 86.44  ? 603 TRP A O   1 
ATOM   4746 C  CB  . TRP A 1 603 ? 121.997 130.733 134.908 1.00 71.98  ? 603 TRP A CB  1 
ATOM   4747 C  CG  . TRP A 1 603 ? 120.958 131.798 135.028 1.00 79.15  ? 603 TRP A CG  1 
ATOM   4748 C  CD1 . TRP A 1 603 ? 120.283 132.161 136.154 1.00 85.51  ? 603 TRP A CD1 1 
ATOM   4749 C  CD2 . TRP A 1 603 ? 120.464 132.636 133.978 1.00 81.25  ? 603 TRP A CD2 1 
ATOM   4750 N  NE1 . TRP A 1 603 ? 119.402 133.173 135.872 1.00 84.15  ? 603 TRP A NE1 1 
ATOM   4751 C  CE2 . TRP A 1 603 ? 119.493 133.483 134.542 1.00 80.14  ? 603 TRP A CE2 1 
ATOM   4752 C  CE3 . TRP A 1 603 ? 120.750 132.750 132.615 1.00 82.43  ? 603 TRP A CE3 1 
ATOM   4753 C  CZ2 . TRP A 1 603 ? 118.809 134.434 133.791 1.00 79.74  ? 603 TRP A CZ2 1 
ATOM   4754 C  CZ3 . TRP A 1 603 ? 120.069 133.694 131.874 1.00 76.16  ? 603 TRP A CZ3 1 
ATOM   4755 C  CH2 . TRP A 1 603 ? 119.111 134.524 132.463 1.00 76.90  ? 603 TRP A CH2 1 
ATOM   4756 N  N   . ASN A 1 604 ? 123.005 127.619 134.296 1.00 90.74  ? 604 ASN A N   1 
ATOM   4757 C  CA  . ASN A 1 604 ? 123.952 126.656 133.755 1.00 85.96  ? 604 ASN A CA  1 
ATOM   4758 C  C   . ASN A 1 604 ? 123.426 126.008 132.486 1.00 92.32  ? 604 ASN A C   1 
ATOM   4759 O  O   . ASN A 1 604 ? 124.182 125.849 131.522 1.00 98.07  ? 604 ASN A O   1 
ATOM   4760 C  CB  . ASN A 1 604 ? 124.267 125.584 134.798 1.00 88.20  ? 604 ASN A CB  1 
ATOM   4761 C  CG  . ASN A 1 604 ? 125.466 124.743 134.423 1.00 96.63  ? 604 ASN A CG  1 
ATOM   4762 O  OD1 . ASN A 1 604 ? 125.333 123.565 134.099 1.00 103.83 ? 604 ASN A OD1 1 
ATOM   4763 N  ND2 . ASN A 1 604 ? 126.648 125.346 134.467 1.00 99.44  ? 604 ASN A ND2 1 
ATOM   4764 N  N   . MET A 1 605 ? 122.148 125.636 132.466 1.00 98.28  ? 605 MET A N   1 
ATOM   4765 C  CA  . MET A 1 605 ? 121.536 125.070 131.270 1.00 93.13  ? 605 MET A CA  1 
ATOM   4766 C  C   . MET A 1 605 ? 121.447 126.074 130.126 1.00 98.28  ? 605 MET A C   1 
ATOM   4767 O  O   . MET A 1 605 ? 121.705 125.717 128.971 1.00 108.65 ? 605 MET A O   1 
ATOM   4768 C  CB  . MET A 1 605 ? 120.139 124.539 131.596 1.00 93.14  ? 605 MET A CB  1 
ATOM   4769 C  CG  . MET A 1 605 ? 119.907 123.104 131.167 1.00 105.44 ? 605 MET A CG  1 
ATOM   4770 S  SD  . MET A 1 605 ? 118.425 122.391 131.903 1.00 127.84 ? 605 MET A SD  1 
ATOM   4771 C  CE  . MET A 1 605 ? 118.646 122.841 133.620 1.00 108.02 ? 605 MET A CE  1 
ATOM   4772 N  N   . ILE A 1 606 ? 121.091 127.323 130.417 1.00 89.88  ? 606 ILE A N   1 
ATOM   4773 C  CA  . ILE A 1 606 ? 120.824 128.285 129.349 1.00 90.22  ? 606 ILE A CA  1 
ATOM   4774 C  C   . ILE A 1 606 ? 122.093 129.022 128.940 1.00 90.60  ? 606 ILE A C   1 
ATOM   4775 O  O   . ILE A 1 606 ? 122.534 128.943 127.788 1.00 97.23  ? 606 ILE A O   1 
ATOM   4776 C  CB  . ILE A 1 606 ? 119.715 129.265 129.773 1.00 90.67  ? 606 ILE A CB  1 
ATOM   4777 C  CG1 . ILE A 1 606 ? 118.368 128.544 129.871 1.00 93.03  ? 606 ILE A CG1 1 
ATOM   4778 C  CG2 . ILE A 1 606 ? 119.619 130.420 128.792 1.00 88.57  ? 606 ILE A CG2 1 
ATOM   4779 C  CD1 . ILE A 1 606 ? 118.113 127.562 128.749 1.00 93.24  ? 606 ILE A CD1 1 
ATOM   4780 N  N   . GLY A 1 607 ? 122.691 129.762 129.873 1.00 85.50  ? 607 GLY A N   1 
ATOM   4781 C  CA  . GLY A 1 607 ? 123.831 130.598 129.525 1.00 86.47  ? 607 GLY A CA  1 
ATOM   4782 C  C   . GLY A 1 607 ? 125.063 129.803 129.139 1.00 89.83  ? 607 GLY A C   1 
ATOM   4783 O  O   . GLY A 1 607 ? 125.764 130.147 128.185 1.00 97.48  ? 607 GLY A O   1 
ATOM   4784 N  N   . ALA A 1 608 ? 125.353 128.738 129.883 1.00 82.69  ? 608 ALA A N   1 
ATOM   4785 C  CA  . ALA A 1 608 ? 126.539 127.939 129.617 1.00 78.29  ? 608 ALA A CA  1 
ATOM   4786 C  C   . ALA A 1 608 ? 126.299 126.823 128.611 1.00 81.33  ? 608 ALA A C   1 
ATOM   4787 O  O   . ALA A 1 608 ? 127.238 126.426 127.912 1.00 81.37  ? 608 ALA A O   1 
ATOM   4788 C  CB  . ALA A 1 608 ? 127.076 127.335 130.917 1.00 79.36  ? 608 ALA A CB  1 
ATOM   4789 N  N   . GLY A 1 609 ? 125.074 126.315 128.513 1.00 90.58  ? 609 GLY A N   1 
ATOM   4790 C  CA  . GLY A 1 609 ? 124.793 125.225 127.604 1.00 88.31  ? 609 GLY A CA  1 
ATOM   4791 C  C   . GLY A 1 609 ? 124.354 125.680 126.229 1.00 85.34  ? 609 GLY A C   1 
ATOM   4792 O  O   . GLY A 1 609 ? 124.944 125.282 125.221 1.00 92.22  ? 609 GLY A O   1 
ATOM   4793 N  N   . VAL A 1 610 ? 123.323 126.521 126.171 1.00 80.88  ? 610 VAL A N   1 
ATOM   4794 C  CA  . VAL A 1 610 ? 122.813 126.989 124.885 1.00 87.14  ? 610 VAL A CA  1 
ATOM   4795 C  C   . VAL A 1 610 ? 123.727 128.055 124.300 1.00 90.29  ? 610 VAL A C   1 
ATOM   4796 O  O   . VAL A 1 610 ? 124.290 127.889 123.213 1.00 101.63 ? 610 VAL A O   1 
ATOM   4797 C  CB  . VAL A 1 610 ? 121.370 127.505 125.037 1.00 90.24  ? 610 VAL A CB  1 
ATOM   4798 C  CG1 . VAL A 1 610 ? 120.899 128.134 123.738 1.00 91.84  ? 610 VAL A CG1 1 
ATOM   4799 C  CG2 . VAL A 1 610 ? 120.447 126.375 125.453 1.00 86.55  ? 610 VAL A CG2 1 
ATOM   4800 N  N   . PHE A 1 611 ? 123.892 129.168 125.018 1.00 84.08  ? 611 PHE A N   1 
ATOM   4801 C  CA  . PHE A 1 611 ? 124.733 130.253 124.526 1.00 86.22  ? 611 PHE A CA  1 
ATOM   4802 C  C   . PHE A 1 611 ? 126.206 129.875 124.503 1.00 89.28  ? 611 PHE A C   1 
ATOM   4803 O  O   . PHE A 1 611 ? 126.956 130.405 123.678 1.00 94.16  ? 611 PHE A O   1 
ATOM   4804 C  CB  . PHE A 1 611 ? 124.523 131.502 125.381 1.00 83.93  ? 611 PHE A CB  1 
ATOM   4805 C  CG  . PHE A 1 611 ? 123.164 132.116 125.226 1.00 89.06  ? 611 PHE A CG  1 
ATOM   4806 C  CD1 . PHE A 1 611 ? 122.541 132.143 123.992 1.00 89.19  ? 611 PHE A CD1 1 
ATOM   4807 C  CD2 . PHE A 1 611 ? 122.503 132.651 126.317 1.00 89.80  ? 611 PHE A CD2 1 
ATOM   4808 C  CE1 . PHE A 1 611 ? 121.289 132.703 123.845 1.00 90.04  ? 611 PHE A CE1 1 
ATOM   4809 C  CE2 . PHE A 1 611 ? 121.249 133.211 126.176 1.00 91.34  ? 611 PHE A CE2 1 
ATOM   4810 C  CZ  . PHE A 1 611 ? 120.642 133.238 124.939 1.00 93.17  ? 611 PHE A CZ  1 
ATOM   4811 N  N   . GLY A 1 612 ? 126.637 128.975 125.385 1.00 85.37  ? 612 GLY A N   1 
ATOM   4812 C  CA  . GLY A 1 612 ? 128.017 128.534 125.370 1.00 84.49  ? 612 GLY A CA  1 
ATOM   4813 C  C   . GLY A 1 612 ? 128.378 127.643 124.204 1.00 87.59  ? 612 GLY A C   1 
ATOM   4814 O  O   . GLY A 1 612 ? 129.528 127.681 123.755 1.00 95.04  ? 612 GLY A O   1 
ATOM   4815 N  N   . PHE A 1 613 ? 127.429 126.861 123.689 1.00 95.39  ? 613 PHE A N   1 
ATOM   4816 C  CA  . PHE A 1 613 ? 127.701 125.971 122.571 1.00 93.61  ? 613 PHE A CA  1 
ATOM   4817 C  C   . PHE A 1 613 ? 127.401 126.602 121.218 1.00 98.19  ? 613 PHE A C   1 
ATOM   4818 O  O   . PHE A 1 613 ? 127.955 126.148 120.213 1.00 104.94 ? 613 PHE A O   1 
ATOM   4819 C  CB  . PHE A 1 613 ? 126.913 124.660 122.716 1.00 86.90  ? 613 PHE A CB  1 
ATOM   4820 C  CG  . PHE A 1 613 ? 127.101 123.710 121.565 1.00 99.45  ? 613 PHE A CG  1 
ATOM   4821 C  CD1 . PHE A 1 613 ? 126.195 123.675 120.517 1.00 101.13 ? 613 PHE A CD1 1 
ATOM   4822 C  CD2 . PHE A 1 613 ? 128.209 122.880 121.515 1.00 105.83 ? 613 PHE A CD2 1 
ATOM   4823 C  CE1 . PHE A 1 613 ? 126.380 122.812 119.452 1.00 105.61 ? 613 PHE A CE1 1 
ATOM   4824 C  CE2 . PHE A 1 613 ? 128.397 122.016 120.454 1.00 106.78 ? 613 PHE A CE2 1 
ATOM   4825 C  CZ  . PHE A 1 613 ? 127.485 121.984 119.421 1.00 108.30 ? 613 PHE A CZ  1 
ATOM   4826 N  N   . LEU A 1 614 ? 126.666 127.682 121.160 1.00 91.05  ? 614 LEU A N   1 
ATOM   4827 C  CA  . LEU A 1 614 ? 126.416 128.230 119.825 1.00 92.50  ? 614 LEU A CA  1 
ATOM   4828 C  C   . LEU A 1 614 ? 127.673 128.952 119.348 1.00 99.43  ? 614 LEU A C   1 
ATOM   4829 O  O   . LEU A 1 614 ? 127.742 129.286 118.195 1.00 105.32 ? 614 LEU A O   1 
ATOM   4830 C  CB  . LEU A 1 614 ? 125.201 129.152 119.949 1.00 93.94  ? 614 LEU A CB  1 
ATOM   4831 C  CG  . LEU A 1 614 ? 123.846 128.448 120.007 1.00 98.61  ? 614 LEU A CG  1 
ATOM   4832 C  CD1 . LEU A 1 614 ? 122.706 129.445 119.893 1.00 97.17  ? 614 LEU A CD1 1 
ATOM   4833 C  CD2 . LEU A 1 614 ? 123.730 127.359 118.954 1.00 99.89  ? 614 LEU A CD2 1 
ATOM   4834 N  N   . ILE A 1 615 ? 128.593 129.233 120.273 1.00 89.41  ? 615 ILE A N   1 
ATOM   4835 C  CA  . ILE A 1 615 ? 129.826 129.997 120.004 1.00 88.57  ? 615 ILE A CA  1 
ATOM   4836 C  C   . ILE A 1 615 ? 131.026 129.047 120.038 1.00 88.86  ? 615 ILE A C   1 
ATOM   4837 O  O   . ILE A 1 615 ? 132.097 129.446 119.595 1.00 96.41  ? 615 ILE A O   1 
ATOM   4838 C  CB  . ILE A 1 615 ? 129.981 131.110 121.060 1.00 89.78  ? 615 ILE A CB  1 
ATOM   4839 C  CG1 . ILE A 1 615 ? 130.283 130.526 122.446 1.00 85.89  ? 615 ILE A CG1 1 
ATOM   4840 C  CG2 . ILE A 1 615 ? 128.779 132.044 121.064 1.00 94.26  ? 615 ILE A CG2 1 
ATOM   4841 C  CD1 . ILE A 1 615 ? 130.689 131.533 123.492 1.00 85.23  ? 615 ILE A CD1 1 
ATOM   4842 N  N   . ASN A 1 616 ? 130.792 127.803 120.377 1.00 84.82  ? 616 ASN A N   1 
ATOM   4843 C  CA  . ASN A 1 616 ? 131.881 126.867 120.621 1.00 81.78  ? 616 ASN A CA  1 
ATOM   4844 C  C   . ASN A 1 616 ? 132.502 126.292 119.348 1.00 86.88  ? 616 ASN A C   1 
ATOM   4845 O  O   . ASN A 1 616 ? 133.736 126.233 119.262 1.00 85.64  ? 616 ASN A O   1 
ATOM   4846 C  CB  . ASN A 1 616 ? 131.402 125.728 121.524 1.00 87.73  ? 616 ASN A CB  1 
ATOM   4847 C  CG  . ASN A 1 616 ? 132.468 124.677 121.744 1.00 88.35  ? 616 ASN A CG  1 
ATOM   4848 O  OD1 . ASN A 1 616 ? 133.552 124.975 122.240 1.00 89.31  ? 616 ASN A OD1 1 
ATOM   4849 N  ND2 . ASN A 1 616 ? 132.167 123.442 121.366 1.00 91.08  ? 616 ASN A ND2 1 
ATOM   4850 N  N   . PRO A 1 617 ? 131.729 125.833 118.362 1.00 82.24  ? 617 PRO A N   1 
ATOM   4851 C  CA  . PRO A 1 617 ? 132.348 125.247 117.177 1.00 79.85  ? 617 PRO A CA  1 
ATOM   4852 C  C   . PRO A 1 617 ? 133.229 126.257 116.478 1.00 85.69  ? 617 PRO A C   1 
ATOM   4853 O  O   . PRO A 1 617 ? 132.897 127.455 116.401 1.00 92.75  ? 617 PRO A O   1 
ATOM   4854 C  CB  . PRO A 1 617 ? 131.145 124.848 116.310 1.00 79.35  ? 617 PRO A CB  1 
ATOM   4855 C  CG  . PRO A 1 617 ? 130.039 124.690 117.255 1.00 74.81  ? 617 PRO A CG  1 
ATOM   4856 C  CD  . PRO A 1 617 ? 130.259 125.755 118.271 1.00 76.90  ? 617 PRO A CD  1 
ATOM   4857 N  N   . PRO A 1 618 ? 134.379 125.821 115.961 1.00 77.71  ? 618 PRO A N   1 
ATOM   4858 C  CA  . PRO A 1 618 ? 135.283 126.771 115.295 1.00 77.19  ? 618 PRO A CA  1 
ATOM   4859 C  C   . PRO A 1 618 ? 134.667 127.444 114.083 1.00 83.31  ? 618 PRO A C   1 
ATOM   4860 O  O   . PRO A 1 618 ? 134.983 128.606 113.806 1.00 94.42  ? 618 PRO A O   1 
ATOM   4861 C  CB  . PRO A 1 618 ? 136.486 125.895 114.920 1.00 77.90  ? 618 PRO A CB  1 
ATOM   4862 C  CG  . PRO A 1 618 ? 136.410 124.723 115.832 1.00 82.93  ? 618 PRO A CG  1 
ATOM   4863 C  CD  . PRO A 1 618 ? 134.955 124.471 116.043 1.00 78.29  ? 618 PRO A CD  1 
ATOM   4864 N  N   . ILE A 1 619 ? 133.785 126.754 113.355 1.00 76.19  ? 619 ILE A N   1 
ATOM   4865 C  CA  . ILE A 1 619 ? 133.149 127.359 112.187 1.00 74.81  ? 619 ILE A CA  1 
ATOM   4866 C  C   . ILE A 1 619 ? 132.302 128.556 112.594 1.00 80.17  ? 619 ILE A C   1 
ATOM   4867 O  O   . ILE A 1 619 ? 132.155 129.513 111.827 1.00 86.39  ? 619 ILE A O   1 
ATOM   4868 C  CB  . ILE A 1 619 ? 132.323 126.310 111.415 1.00 73.44  ? 619 ILE A CB  1 
ATOM   4869 C  CG1 . ILE A 1 619 ? 131.912 126.851 110.044 1.00 77.69  ? 619 ILE A CG1 1 
ATOM   4870 C  CG2 . ILE A 1 619 ? 131.093 125.890 112.203 1.00 76.95  ? 619 ILE A CG2 1 
ATOM   4871 C  CD1 . ILE A 1 619 ? 133.014 127.577 109.314 1.00 76.30  ? 619 ILE A CD1 1 
ATOM   4872 N  N   . SER A 1 620 ? 131.744 128.563 113.788 1.00 72.19  ? 620 SER A N   1 
ATOM   4873 C  CA  . SER A 1 620 ? 130.993 129.718 114.317 1.00 72.43  ? 620 SER A CA  1 
ATOM   4874 C  C   . SER A 1 620 ? 131.965 130.744 114.879 1.00 72.72  ? 620 SER A C   1 
ATOM   4875 O  O   . SER A 1 620 ? 131.871 131.896 114.522 1.00 84.95  ? 620 SER A O   1 
ATOM   4876 C  CB  . SER A 1 620 ? 130.030 129.267 115.352 1.00 75.95  ? 620 SER A CB  1 
ATOM   4877 O  OG  . SER A 1 620 ? 129.317 130.355 115.894 1.00 81.19  ? 620 SER A OG  1 
ATOM   4878 N  N   . LEU A 1 621 ? 132.880 130.288 115.720 1.00 62.01  ? 621 LEU A N   1 
ATOM   4879 C  CA  . LEU A 1 621 ? 133.772 131.238 116.376 1.00 59.72  ? 621 LEU A CA  1 
ATOM   4880 C  C   . LEU A 1 621 ? 134.591 132.036 115.369 1.00 69.71  ? 621 LEU A C   1 
ATOM   4881 O  O   . LEU A 1 621 ? 134.975 133.175 115.656 1.00 81.96  ? 621 LEU A O   1 
ATOM   4882 C  CB  . LEU A 1 621 ? 134.695 130.510 117.352 1.00 67.99  ? 621 LEU A CB  1 
ATOM   4883 C  CG  . LEU A 1 621 ? 135.260 131.345 118.503 1.00 76.40  ? 621 LEU A CG  1 
ATOM   4884 C  CD1 . LEU A 1 621 ? 134.200 132.267 119.080 1.00 77.68  ? 621 LEU A CD1 1 
ATOM   4885 C  CD2 . LEU A 1 621 ? 135.838 130.453 119.585 1.00 77.81  ? 621 LEU A CD2 1 
ATOM   4886 N  N   . PHE A 1 622 ? 134.845 131.469 114.184 1.00 70.84  ? 622 PHE A N   1 
ATOM   4887 C  CA  . PHE A 1 622 ? 135.598 132.171 113.150 1.00 69.64  ? 622 PHE A CA  1 
ATOM   4888 C  C   . PHE A 1 622 ? 134.968 133.515 112.804 1.00 74.77  ? 622 PHE A C   1 
ATOM   4889 O  O   . PHE A 1 622 ? 135.685 134.480 112.525 1.00 77.50  ? 622 PHE A O   1 
ATOM   4890 C  CB  . PHE A 1 622 ? 135.700 131.293 111.903 1.00 59.26  ? 622 PHE A CB  1 
ATOM   4891 C  CG  . PHE A 1 622 ? 136.593 131.852 110.834 1.00 56.08  ? 622 PHE A CG  1 
ATOM   4892 C  CD1 . PHE A 1 622 ? 137.947 131.567 110.827 1.00 68.28  ? 622 PHE A CD1 1 
ATOM   4893 C  CD2 . PHE A 1 622 ? 136.080 132.656 109.830 1.00 65.04  ? 622 PHE A CD2 1 
ATOM   4894 C  CE1 . PHE A 1 622 ? 138.769 132.077 109.845 1.00 74.76  ? 622 PHE A CE1 1 
ATOM   4895 C  CE2 . PHE A 1 622 ? 136.898 133.168 108.849 1.00 68.66  ? 622 PHE A CE2 1 
ATOM   4896 C  CZ  . PHE A 1 622 ? 138.244 132.877 108.857 1.00 72.95  ? 622 PHE A CZ  1 
ATOM   4897 N  N   . TYR A 1 623 ? 133.639 133.595 112.813 1.00 68.75  ? 623 TYR A N   1 
ATOM   4898 C  CA  . TYR A 1 623 ? 132.943 134.850 112.581 1.00 61.09  ? 623 TYR A CA  1 
ATOM   4899 C  C   . TYR A 1 623 ? 132.463 135.516 113.860 1.00 66.80  ? 623 TYR A C   1 
ATOM   4900 O  O   . TYR A 1 623 ? 132.273 136.736 113.868 1.00 76.49  ? 623 TYR A O   1 
ATOM   4901 C  CB  . TYR A 1 623 ? 131.737 134.629 111.660 1.00 61.20  ? 623 TYR A CB  1 
ATOM   4902 C  CG  . TYR A 1 623 ? 132.048 133.868 110.395 1.00 63.51  ? 623 TYR A CG  1 
ATOM   4903 C  CD1 . TYR A 1 623 ? 132.578 134.514 109.287 1.00 73.59  ? 623 TYR A CD1 1 
ATOM   4904 C  CD2 . TYR A 1 623 ? 131.810 132.504 110.305 1.00 60.82  ? 623 TYR A CD2 1 
ATOM   4905 C  CE1 . TYR A 1 623 ? 132.862 133.824 108.129 1.00 75.07  ? 623 TYR A CE1 1 
ATOM   4906 C  CE2 . TYR A 1 623 ? 132.092 131.806 109.149 1.00 65.97  ? 623 TYR A CE2 1 
ATOM   4907 C  CZ  . TYR A 1 623 ? 132.618 132.471 108.065 1.00 74.56  ? 623 TYR A CZ  1 
ATOM   4908 O  OH  . TYR A 1 623 ? 132.899 131.781 106.911 1.00 74.55  ? 623 TYR A OH  1 
ATOM   4909 N  N   . ILE A 1 624 ? 132.357 134.861 114.968 1.00 73.92  ? 624 ILE A N   1 
ATOM   4910 C  CA  . ILE A 1 624 ? 131.637 135.628 115.994 1.00 67.29  ? 624 ILE A CA  1 
ATOM   4911 C  C   . ILE A 1 624 ? 132.585 135.946 117.140 1.00 78.26  ? 624 ILE A C   1 
ATOM   4912 O  O   . ILE A 1 624 ? 132.138 136.541 118.074 1.00 83.68  ? 624 ILE A O   1 
ATOM   4913 C  CB  . ILE A 1 624 ? 130.340 134.893 116.369 1.00 77.76  ? 624 ILE A CB  1 
ATOM   4914 C  CG1 . ILE A 1 624 ? 130.595 133.563 117.073 1.00 76.74  ? 624 ILE A CG1 1 
ATOM   4915 C  CG2 . ILE A 1 624 ? 129.461 134.728 115.143 1.00 75.41  ? 624 ILE A CG2 1 
ATOM   4916 C  CD1 . ILE A 1 624 ? 129.341 132.922 117.589 1.00 70.96  ? 624 ILE A CD1 1 
ATOM   4917 N  N   . GLN A 1 625 ? 133.846 135.569 117.044 1.00 74.57  ? 625 GLN A N   1 
ATOM   4918 C  CA  . GLN A 1 625 ? 134.835 135.964 118.075 1.00 69.71  ? 625 GLN A CA  1 
ATOM   4919 C  C   . GLN A 1 625 ? 135.039 137.466 118.052 1.00 84.62  ? 625 GLN A C   1 
ATOM   4920 O  O   . GLN A 1 625 ? 135.392 137.991 117.013 1.00 87.28  ? 625 GLN A O   1 
ATOM   4921 C  CB  . GLN A 1 625 ? 136.208 135.354 117.873 1.00 69.08  ? 625 GLN A CB  1 
ATOM   4922 C  CG  . GLN A 1 625 ? 137.188 135.741 118.960 1.00 76.85  ? 625 GLN A CG  1 
ATOM   4923 C  CD  . GLN A 1 625 ? 138.304 134.743 119.090 1.00 85.56  ? 625 GLN A CD  1 
ATOM   4924 O  OE1 . GLN A 1 625 ? 139.475 135.065 118.931 1.00 91.16  ? 625 GLN A OE1 1 
ATOM   4925 N  NE2 . GLN A 1 625 ? 137.944 133.512 119.391 1.00 84.15  ? 625 GLN A NE2 1 
ATOM   4926 N  N   . GLY A 1 626 ? 134.805 138.097 119.185 1.00 78.35  ? 626 GLY A N   1 
ATOM   4927 C  CA  . GLY A 1 626 ? 134.910 139.535 119.292 1.00 72.95  ? 626 GLY A CA  1 
ATOM   4928 C  C   . GLY A 1 626 ? 133.609 140.295 119.167 1.00 72.93  ? 626 GLY A C   1 
ATOM   4929 O  O   . GLY A 1 626 ? 133.639 141.530 119.135 1.00 83.16  ? 626 GLY A O   1 
ATOM   4930 N  N   . LEU A 1 627 ? 132.476 139.608 119.096 1.00 64.77  ? 627 LEU A N   1 
ATOM   4931 C  CA  . LEU A 1 627 ? 131.177 140.247 118.946 1.00 68.37  ? 627 LEU A CA  1 
ATOM   4932 C  C   . LEU A 1 627 ? 130.416 140.217 120.267 1.00 68.58  ? 627 LEU A C   1 
ATOM   4933 O  O   . LEU A 1 627 ? 130.908 139.728 121.286 1.00 73.75  ? 627 LEU A O   1 
ATOM   4934 C  CB  . LEU A 1 627 ? 130.368 139.569 117.834 1.00 60.71  ? 627 LEU A CB  1 
ATOM   4935 C  CG  . LEU A 1 627 ? 131.064 139.542 116.471 1.00 59.96  ? 627 LEU A CG  1 
ATOM   4936 C  CD1 . LEU A 1 627 ? 130.171 138.927 115.413 1.00 66.21  ? 627 LEU A CD1 1 
ATOM   4937 C  CD2 . LEU A 1 627 ? 131.495 140.939 116.063 1.00 66.11  ? 627 LEU A CD2 1 
ATOM   4938 N  N   . ASN A 1 628 ? 129.195 140.754 120.237 1.00 62.91  ? 628 ASN A N   1 
ATOM   4939 C  CA  . ASN A 1 628 ? 128.417 140.909 121.461 1.00 64.91  ? 628 ASN A CA  1 
ATOM   4940 C  C   . ASN A 1 628 ? 127.830 139.594 121.957 1.00 72.13  ? 628 ASN A C   1 
ATOM   4941 O  O   . ASN A 1 628 ? 127.389 139.524 123.109 1.00 79.69  ? 628 ASN A O   1 
ATOM   4942 C  CB  . ASN A 1 628 ? 127.304 141.932 121.251 1.00 62.98  ? 628 ASN A CB  1 
ATOM   4943 C  CG  . ASN A 1 628 ? 127.759 143.348 121.527 1.00 69.50  ? 628 ASN A CG  1 
ATOM   4944 O  OD1 . ASN A 1 628 ? 128.642 143.873 120.852 1.00 73.29  ? 628 ASN A OD1 1 
ATOM   4945 N  ND2 . ASN A 1 628 ? 127.160 143.975 122.529 1.00 70.11  ? 628 ASN A ND2 1 
ATOM   4946 N  N   . THR A 1 629 ? 127.800 138.559 121.117 1.00 70.20  ? 629 THR A N   1 
ATOM   4947 C  CA  . THR A 1 629 ? 127.377 137.244 121.587 1.00 68.40  ? 629 THR A CA  1 
ATOM   4948 C  C   . THR A 1 629 ? 128.307 136.733 122.679 1.00 69.76  ? 629 THR A C   1 
ATOM   4949 O  O   . THR A 1 629 ? 127.874 136.029 123.601 1.00 76.75  ? 629 THR A O   1 
ATOM   4950 C  CB  . THR A 1 629 ? 127.322 136.264 120.417 1.00 73.48  ? 629 THR A CB  1 
ATOM   4951 O  OG1 . THR A 1 629 ? 128.437 136.499 119.554 1.00 87.94  ? 629 THR A OG1 1 
ATOM   4952 C  CG2 . THR A 1 629 ? 126.038 136.443 119.629 1.00 75.28  ? 629 THR A CG2 1 
ATOM   4953 N  N   . SER A 1 630 ? 129.590 137.087 122.594 1.00 72.01  ? 630 SER A N   1 
ATOM   4954 C  CA  . SER A 1 630 ? 130.526 136.757 123.662 1.00 69.20  ? 630 SER A CA  1 
ATOM   4955 C  C   . SER A 1 630 ? 130.124 137.441 124.962 1.00 70.14  ? 630 SER A C   1 
ATOM   4956 O  O   . SER A 1 630 ? 130.207 136.845 126.039 1.00 80.72  ? 630 SER A O   1 
ATOM   4957 C  CB  . SER A 1 630 ? 131.944 137.154 123.254 1.00 71.26  ? 630 SER A CB  1 
ATOM   4958 O  OG  . SER A 1 630 ? 132.420 136.331 122.205 1.00 86.52  ? 630 SER A OG  1 
ATOM   4959 N  N   . ALA A 1 631 ? 129.682 138.698 124.879 1.00 69.42  ? 631 ALA A N   1 
ATOM   4960 C  CA  . ALA A 1 631 ? 129.201 139.395 126.066 1.00 69.97  ? 631 ALA A CA  1 
ATOM   4961 C  C   . ALA A 1 631 ? 127.949 138.734 126.625 1.00 63.58  ? 631 ALA A C   1 
ATOM   4962 O  O   . ALA A 1 631 ? 127.792 138.616 127.847 1.00 71.04  ? 631 ALA A O   1 
ATOM   4963 C  CB  . ALA A 1 631 ? 128.936 140.864 125.741 1.00 65.29  ? 631 ALA A CB  1 
ATOM   4964 N  N   . VAL A 1 632 ? 127.044 138.302 125.744 1.00 62.37  ? 632 VAL A N   1 
ATOM   4965 C  CA  . VAL A 1 632 ? 125.837 137.604 126.186 1.00 56.45  ? 632 VAL A CA  1 
ATOM   4966 C  C   . VAL A 1 632 ? 126.207 136.354 126.970 1.00 61.79  ? 632 VAL A C   1 
ATOM   4967 O  O   . VAL A 1 632 ? 125.735 136.133 128.095 1.00 70.74  ? 632 VAL A O   1 
ATOM   4968 C  CB  . VAL A 1 632 ? 124.949 137.253 124.978 1.00 59.98  ? 632 VAL A CB  1 
ATOM   4969 C  CG1 . VAL A 1 632 ? 123.768 136.401 125.410 1.00 57.72  ? 632 VAL A CG1 1 
ATOM   4970 C  CG2 . VAL A 1 632 ? 124.487 138.504 124.268 1.00 65.64  ? 632 VAL A CG2 1 
ATOM   4971 N  N   . HIS A 1 633 ? 127.074 135.522 126.385 1.00 67.71  ? 633 HIS A N   1 
ATOM   4972 C  CA  . HIS A 1 633 ? 127.479 134.287 127.046 1.00 65.32  ? 633 HIS A CA  1 
ATOM   4973 C  C   . HIS A 1 633 ? 128.209 134.573 128.349 1.00 65.41  ? 633 HIS A C   1 
ATOM   4974 O  O   . HIS A 1 633 ? 127.970 133.904 129.359 1.00 74.78  ? 633 HIS A O   1 
ATOM   4975 C  CB  . HIS A 1 633 ? 128.359 133.453 126.116 1.00 68.28  ? 633 HIS A CB  1 
ATOM   4976 C  CG  . HIS A 1 633 ? 129.149 132.396 126.823 1.00 63.92  ? 633 HIS A CG  1 
ATOM   4977 N  ND1 . HIS A 1 633 ? 128.559 131.321 127.449 1.00 70.67  ? 633 HIS A ND1 1 
ATOM   4978 C  CD2 . HIS A 1 633 ? 130.481 132.256 127.011 1.00 64.80  ? 633 HIS A CD2 1 
ATOM   4979 C  CE1 . HIS A 1 633 ? 129.495 130.560 127.987 1.00 77.21  ? 633 HIS A CE1 1 
ATOM   4980 N  NE2 . HIS A 1 633 ? 130.671 131.106 127.737 1.00 73.27  ? 633 HIS A NE2 1 
ATOM   4981 N  N   . ALA A 1 634 ? 129.102 135.565 128.346 1.00 60.19  ? 634 ALA A N   1 
ATOM   4982 C  CA  . ALA A 1 634 ? 129.856 135.891 129.547 1.00 57.06  ? 634 ALA A CA  1 
ATOM   4983 C  C   . ALA A 1 634 ? 128.927 136.295 130.681 1.00 56.57  ? 634 ALA A C   1 
ATOM   4984 O  O   . ALA A 1 634 ? 128.997 135.736 131.780 1.00 72.00  ? 634 ALA A O   1 
ATOM   4985 C  CB  . ALA A 1 634 ? 130.856 137.007 129.248 1.00 65.00  ? 634 ALA A CB  1 
ATOM   4986 N  N   . HIS A 1 635 ? 128.030 137.247 130.423 1.00 64.14  ? 635 HIS A N   1 
ATOM   4987 C  CA  . HIS A 1 635 ? 127.113 137.679 131.470 1.00 64.80  ? 635 HIS A CA  1 
ATOM   4988 C  C   . HIS A 1 635 ? 126.266 136.518 131.968 1.00 72.38  ? 635 HIS A C   1 
ATOM   4989 O  O   . HIS A 1 635 ? 126.262 136.224 133.171 1.00 76.33  ? 635 HIS A O   1 
ATOM   4990 C  CB  . HIS A 1 635 ? 126.230 138.813 130.960 1.00 58.01  ? 635 HIS A CB  1 
ATOM   4991 C  CG  . HIS A 1 635 ? 126.884 140.156 131.031 1.00 58.52  ? 635 HIS A CG  1 
ATOM   4992 N  ND1 . HIS A 1 635 ? 127.589 140.696 129.977 1.00 80.71  ? 635 HIS A ND1 1 
ATOM   4993 C  CD2 . HIS A 1 635 ? 126.951 141.064 132.032 1.00 64.36  ? 635 HIS A CD2 1 
ATOM   4994 C  CE1 . HIS A 1 635 ? 128.057 141.881 130.326 1.00 85.04  ? 635 HIS A CE1 1 
ATOM   4995 N  NE2 . HIS A 1 635 ? 127.683 142.128 131.567 1.00 83.77  ? 635 HIS A NE2 1 
ATOM   4996 N  N   . ALA A 1 636 ? 125.601 135.807 131.051 1.00 67.71  ? 636 ALA A N   1 
ATOM   4997 C  CA  . ALA A 1 636 ? 124.734 134.704 131.450 1.00 55.72  ? 636 ALA A CA  1 
ATOM   4998 C  C   . ALA A 1 636 ? 125.493 133.680 132.282 1.00 60.53  ? 636 ALA A C   1 
ATOM   4999 O  O   . ALA A 1 636 ? 125.186 133.475 133.462 1.00 69.10  ? 636 ALA A O   1 
ATOM   5000 C  CB  . ALA A 1 636 ? 124.123 134.048 130.211 1.00 63.94  ? 636 ALA A CB  1 
ATOM   5001 N  N   . ALA A 1 637 ? 126.511 133.050 131.695 1.00 57.49  ? 637 ALA A N   1 
ATOM   5002 C  CA  . ALA A 1 637 ? 127.255 132.014 132.400 1.00 57.59  ? 637 ALA A CA  1 
ATOM   5003 C  C   . ALA A 1 637 ? 127.828 132.536 133.712 1.00 61.73  ? 637 ALA A C   1 
ATOM   5004 O  O   . ALA A 1 637 ? 127.464 132.057 134.793 1.00 78.95  ? 637 ALA A O   1 
ATOM   5005 C  CB  . ALA A 1 637 ? 128.366 131.468 131.502 1.00 63.79  ? 637 ALA A CB  1 
ATOM   5006 N  N   . LEU A 1 638 ? 128.718 133.532 133.637 1.00 52.96  ? 638 LEU A N   1 
ATOM   5007 C  CA  . LEU A 1 638 ? 129.421 134.016 134.815 1.00 54.09  ? 638 LEU A CA  1 
ATOM   5008 C  C   . LEU A 1 638 ? 128.459 134.395 135.930 1.00 62.58  ? 638 LEU A C   1 
ATOM   5009 O  O   . LEU A 1 638 ? 128.512 133.788 137.006 1.00 81.13  ? 638 LEU A O   1 
ATOM   5010 C  CB  . LEU A 1 638 ? 130.310 135.212 134.466 1.00 59.59  ? 638 LEU A CB  1 
ATOM   5011 C  CG  . LEU A 1 638 ? 131.293 135.611 135.570 1.00 54.95  ? 638 LEU A CG  1 
ATOM   5012 C  CD1 . LEU A 1 638 ? 132.042 134.397 136.093 1.00 64.03  ? 638 LEU A CD1 1 
ATOM   5013 C  CD2 . LEU A 1 638 ? 132.265 136.670 135.087 1.00 54.60  ? 638 LEU A CD2 1 
ATOM   5014 N  N   . PHE A 1 639 ? 127.578 135.383 135.814 1.00 67.44  ? 639 PHE A N   1 
ATOM   5015 C  CA  . PHE A 1 639 ? 126.690 135.692 136.971 1.00 64.14  ? 639 PHE A CA  1 
ATOM   5016 C  C   . PHE A 1 639 ? 125.672 134.590 137.253 1.00 77.53  ? 639 PHE A C   1 
ATOM   5017 O  O   . PHE A 1 639 ? 125.549 134.253 138.414 1.00 85.04  ? 639 PHE A O   1 
ATOM   5018 C  CB  . PHE A 1 639 ? 125.902 136.994 136.841 1.00 62.65  ? 639 PHE A CB  1 
ATOM   5019 C  CG  . PHE A 1 639 ? 125.017 137.297 138.019 1.00 75.29  ? 639 PHE A CG  1 
ATOM   5020 C  CD1 . PHE A 1 639 ? 125.552 137.738 139.215 1.00 74.13  ? 639 PHE A CD1 1 
ATOM   5021 C  CD2 . PHE A 1 639 ? 123.653 137.085 137.949 1.00 80.99  ? 639 PHE A CD2 1 
ATOM   5022 C  CE1 . PHE A 1 639 ? 124.740 137.985 140.307 1.00 69.09  ? 639 PHE A CE1 1 
ATOM   5023 C  CE2 . PHE A 1 639 ? 122.842 137.331 139.044 1.00 79.54  ? 639 PHE A CE2 1 
ATOM   5024 C  CZ  . PHE A 1 639 ? 123.388 137.784 140.218 1.00 73.87  ? 639 PHE A CZ  1 
ATOM   5025 N  N   . GLY A 1 640 ? 125.020 134.057 136.224 1.00 71.57  ? 640 GLY A N   1 
ATOM   5026 C  CA  . GLY A 1 640 ? 123.955 133.081 136.426 1.00 63.72  ? 640 GLY A CA  1 
ATOM   5027 C  C   . GLY A 1 640 ? 124.427 131.817 137.127 1.00 63.70  ? 640 GLY A C   1 
ATOM   5028 O  O   . GLY A 1 640 ? 123.648 131.263 137.886 1.00 80.66  ? 640 GLY A O   1 
ATOM   5029 N  N   . VAL A 1 641 ? 125.668 131.383 136.928 1.00 64.95  ? 641 VAL A N   1 
ATOM   5030 C  CA  . VAL A 1 641 ? 126.153 130.216 137.697 1.00 62.77  ? 641 VAL A CA  1 
ATOM   5031 C  C   . VAL A 1 641 ? 126.921 130.682 138.933 1.00 71.77  ? 641 VAL A C   1 
ATOM   5032 O  O   . VAL A 1 641 ? 126.407 130.458 139.997 1.00 85.68  ? 641 VAL A O   1 
ATOM   5033 C  CB  . VAL A 1 641 ? 126.911 129.145 136.828 1.00 60.08  ? 641 VAL A CB  1 
ATOM   5034 C  CG1 . VAL A 1 641 ? 127.309 127.897 137.586 1.00 75.55  ? 641 VAL A CG1 1 
ATOM   5035 C  CG2 . VAL A 1 641 ? 126.155 128.818 135.548 1.00 66.53  ? 641 VAL A CG2 1 
ATOM   5036 N  N   . TYR A 1 642 ? 128.031 131.361 138.759 1.00 75.70  ? 642 TYR A N   1 
ATOM   5037 C  CA  . TYR A 1 642 ? 128.976 131.628 139.877 1.00 74.49  ? 642 TYR A CA  1 
ATOM   5038 C  C   . TYR A 1 642 ? 128.640 132.810 140.775 1.00 84.13  ? 642 TYR A C   1 
ATOM   5039 O  O   . TYR A 1 642 ? 128.923 132.680 141.941 1.00 98.23  ? 642 TYR A O   1 
ATOM   5040 C  CB  . TYR A 1 642 ? 130.418 131.700 139.350 1.00 77.26  ? 642 TYR A CB  1 
ATOM   5041 C  CG  . TYR A 1 642 ? 130.951 130.443 138.724 1.00 80.56  ? 642 TYR A CG  1 
ATOM   5042 C  CD1 . TYR A 1 642 ? 131.538 129.458 139.496 1.00 82.16  ? 642 TYR A CD1 1 
ATOM   5043 C  CD2 . TYR A 1 642 ? 130.854 130.242 137.360 1.00 86.38  ? 642 TYR A CD2 1 
ATOM   5044 C  CE1 . TYR A 1 642 ? 132.024 128.296 138.924 1.00 82.74  ? 642 TYR A CE1 1 
ATOM   5045 C  CE2 . TYR A 1 642 ? 131.329 129.088 136.776 1.00 88.32  ? 642 TYR A CE2 1 
ATOM   5046 C  CZ  . TYR A 1 642 ? 131.920 128.119 137.558 1.00 86.63  ? 642 TYR A CZ  1 
ATOM   5047 O  OH  . TYR A 1 642 ? 132.387 126.997 136.955 1.00 94.36  ? 642 TYR A OH  1 
ATOM   5048 N  N   . GLY A 1 643 ? 128.037 133.868 140.266 1.00 73.86  ? 643 GLY A N   1 
ATOM   5049 C  CA  . GLY A 1 643 ? 127.579 134.933 141.136 1.00 77.72  ? 643 GLY A CA  1 
ATOM   5050 C  C   . GLY A 1 643 ? 126.433 134.483 142.020 1.00 81.31  ? 643 GLY A C   1 
ATOM   5051 O  O   . GLY A 1 643 ? 126.384 134.804 143.207 1.00 91.82  ? 643 GLY A O   1 
ATOM   5052 N  N   . PHE A 1 644 ? 125.505 133.712 141.451 1.00 69.65  ? 644 PHE A N   1 
ATOM   5053 C  CA  . PHE A 1 644 ? 124.414 133.170 142.248 1.00 71.14  ? 644 PHE A CA  1 
ATOM   5054 C  C   . PHE A 1 644 ? 124.924 132.159 143.268 1.00 75.00  ? 644 PHE A C   1 
ATOM   5055 O  O   . PHE A 1 644 ? 124.443 132.123 144.406 1.00 84.56  ? 644 PHE A O   1 
ATOM   5056 C  CB  . PHE A 1 644 ? 123.358 132.542 141.340 1.00 68.40  ? 644 PHE A CB  1 
ATOM   5057 C  CG  . PHE A 1 644 ? 122.205 133.454 141.041 1.00 72.88  ? 644 PHE A CG  1 
ATOM   5058 C  CD1 . PHE A 1 644 ? 121.544 134.108 142.062 1.00 75.51  ? 644 PHE A CD1 1 
ATOM   5059 C  CD2 . PHE A 1 644 ? 121.790 133.664 139.737 1.00 80.04  ? 644 PHE A CD2 1 
ATOM   5060 C  CE1 . PHE A 1 644 ? 120.487 134.951 141.792 1.00 77.15  ? 644 PHE A CE1 1 
ATOM   5061 C  CE2 . PHE A 1 644 ? 120.735 134.507 139.462 1.00 82.23  ? 644 PHE A CE2 1 
ATOM   5062 C  CZ  . PHE A 1 644 ? 120.083 135.150 140.491 1.00 80.94  ? 644 PHE A CZ  1 
ATOM   5063 N  N   . LEU A 1 645 ? 125.909 131.339 142.890 1.00 76.49  ? 645 LEU A N   1 
ATOM   5064 C  CA  . LEU A 1 645 ? 126.496 130.404 143.845 1.00 74.86  ? 645 LEU A CA  1 
ATOM   5065 C  C   . LEU A 1 645 ? 127.146 131.143 145.010 1.00 82.75  ? 645 LEU A C   1 
ATOM   5066 O  O   . LEU A 1 645 ? 126.956 130.779 146.176 1.00 97.55  ? 645 LEU A O   1 
ATOM   5067 C  CB  . LEU A 1 645 ? 127.516 129.510 143.139 1.00 78.71  ? 645 LEU A CB  1 
ATOM   5068 C  CG  . LEU A 1 645 ? 127.004 128.184 142.575 1.00 78.87  ? 645 LEU A CG  1 
ATOM   5069 C  CD1 . LEU A 1 645 ? 128.140 127.410 141.934 1.00 81.53  ? 645 LEU A CD1 1 
ATOM   5070 C  CD2 . LEU A 1 645 ? 126.339 127.358 143.662 1.00 80.68  ? 645 LEU A CD2 1 
ATOM   5071 N  N   . ALA A 1 646 ? 127.913 132.192 144.711 1.00 66.75  ? 646 ALA A N   1 
ATOM   5072 C  CA  . ALA A 1 646 ? 128.585 132.949 145.762 1.00 64.79  ? 646 ALA A CA  1 
ATOM   5073 C  C   . ALA A 1 646 ? 127.586 133.695 146.636 1.00 74.55  ? 646 ALA A C   1 
ATOM   5074 O  O   . ALA A 1 646 ? 127.765 133.790 147.856 1.00 85.33  ? 646 ALA A O   1 
ATOM   5075 C  CB  . ALA A 1 646 ? 129.592 133.920 145.147 1.00 65.53  ? 646 ALA A CB  1 
ATOM   5076 N  N   . LEU A 1 647 ? 126.572 134.309 146.049 1.00 69.71  ? 647 LEU A N   1 
ATOM   5077 C  CA  . LEU A 1 647 ? 125.482 134.951 146.826 1.00 68.68  ? 647 LEU A CA  1 
ATOM   5078 C  C   . LEU A 1 647 ? 124.761 133.953 147.730 1.00 74.17  ? 647 LEU A C   1 
ATOM   5079 O  O   . LEU A 1 647 ? 124.567 134.294 148.860 1.00 81.89  ? 647 LEU A O   1 
ATOM   5080 C  CB  . LEU A 1 647 ? 124.538 135.705 145.881 1.00 66.37  ? 647 LEU A CB  1 
ATOM   5081 C  CG  . LEU A 1 647 ? 125.105 136.927 145.168 1.00 68.83  ? 647 LEU A CG  1 
ATOM   5082 C  CD1 . LEU A 1 647 ? 124.133 137.420 144.104 1.00 79.37  ? 647 LEU A CD1 1 
ATOM   5083 C  CD2 . LEU A 1 647 ? 125.442 138.037 146.147 1.00 65.62  ? 647 LEU A CD2 1 
ATOM   5084 N  N   . GLY A 1 648 ? 124.460 132.762 147.241 1.00 76.82  ? 648 GLY A N   1 
ATOM   5085 C  CA  . GLY A 1 648 ? 123.869 131.758 148.107 1.00 75.12  ? 648 GLY A CA  1 
ATOM   5086 C  C   . GLY A 1 648 ? 124.805 131.335 149.220 1.00 78.51  ? 648 GLY A C   1 
ATOM   5087 O  O   . GLY A 1 648 ? 124.380 131.137 150.358 1.00 91.33  ? 648 GLY A O   1 
ATOM   5088 N  N   . PHE A 1 649 ? 126.097 131.212 148.909 1.00 76.67  ? 649 PHE A N   1 
ATOM   5089 C  CA  . PHE A 1 649 ? 127.076 130.831 149.921 1.00 74.52  ? 649 PHE A CA  1 
ATOM   5090 C  C   . PHE A 1 649 ? 127.157 131.871 151.032 1.00 82.77  ? 649 PHE A C   1 
ATOM   5091 O  O   . PHE A 1 649 ? 127.123 131.533 152.220 1.00 87.60  ? 649 PHE A O   1 
ATOM   5092 C  CB  . PHE A 1 649 ? 128.444 130.636 149.269 1.00 70.74  ? 649 PHE A CB  1 
ATOM   5093 C  CG  . PHE A 1 649 ? 128.629 129.288 148.638 1.00 82.32  ? 649 PHE A CG  1 
ATOM   5094 C  CD1 . PHE A 1 649 ? 127.687 128.290 148.819 1.00 84.86  ? 649 PHE A CD1 1 
ATOM   5095 C  CD2 . PHE A 1 649 ? 129.733 129.025 147.849 1.00 86.21  ? 649 PHE A CD2 1 
ATOM   5096 C  CE1 . PHE A 1 649 ? 127.852 127.051 148.235 1.00 84.53  ? 649 PHE A CE1 1 
ATOM   5097 C  CE2 . PHE A 1 649 ? 129.901 127.789 147.262 1.00 86.54  ? 649 PHE A CE2 1 
ATOM   5098 C  CZ  . PHE A 1 649 ? 128.959 126.801 147.456 1.00 87.34  ? 649 PHE A CZ  1 
ATOM   5099 N  N   . VAL A 1 650 ? 127.187 133.140 150.699 1.00 76.05  ? 650 VAL A N   1 
ATOM   5100 C  CA  . VAL A 1 650 ? 127.398 134.170 151.747 1.00 74.10  ? 650 VAL A CA  1 
ATOM   5101 C  C   . VAL A 1 650 ? 126.077 134.409 152.465 1.00 79.39  ? 650 VAL A C   1 
ATOM   5102 O  O   . VAL A 1 650 ? 126.124 134.730 153.627 1.00 90.78  ? 650 VAL A O   1 
ATOM   5103 C  CB  . VAL A 1 650 ? 128.020 135.468 151.200 1.00 68.31  ? 650 VAL A CB  1 
ATOM   5104 C  CG1 . VAL A 1 650 ? 129.437 135.259 150.701 1.00 75.17  ? 650 VAL A CG1 1 
ATOM   5105 C  CG2 . VAL A 1 650 ? 127.154 136.146 150.155 1.00 77.70  ? 650 VAL A CG2 1 
ATOM   5106 N  N   . LEU A 1 651 ? 124.949 134.179 151.804 1.00 79.15  ? 651 LEU A N   1 
ATOM   5107 C  CA  . LEU A 1 651 ? 123.678 134.238 152.518 1.00 79.94  ? 651 LEU A CA  1 
ATOM   5108 C  C   . LEU A 1 651 ? 123.556 133.091 153.515 1.00 84.14  ? 651 LEU A C   1 
ATOM   5109 O  O   . LEU A 1 651 ? 123.083 133.278 154.642 1.00 90.80  ? 651 LEU A O   1 
ATOM   5110 C  CB  . LEU A 1 651 ? 122.518 134.213 151.520 1.00 82.09  ? 651 LEU A CB  1 
ATOM   5111 C  CG  . LEU A 1 651 ? 122.214 135.531 150.809 1.00 80.53  ? 651 LEU A CG  1 
ATOM   5112 C  CD1 . LEU A 1 651 ? 120.976 135.395 149.944 1.00 85.63  ? 651 LEU A CD1 1 
ATOM   5113 C  CD2 . LEU A 1 651 ? 122.050 136.661 151.811 1.00 80.55  ? 651 LEU A CD2 1 
ATOM   5114 N  N   . LEU A 1 652 ? 123.941 131.896 153.127 1.00 79.54  ? 652 LEU A N   1 
ATOM   5115 C  CA  . LEU A 1 652 ? 123.925 130.734 154.039 1.00 83.34  ? 652 LEU A CA  1 
ATOM   5116 C  C   . LEU A 1 652 ? 124.925 130.925 155.183 1.00 88.19  ? 652 LEU A C   1 
ATOM   5117 O  O   . LEU A 1 652 ? 124.598 130.509 156.274 1.00 94.32  ? 652 LEU A O   1 
ATOM   5118 C  CB  . LEU A 1 652 ? 124.214 129.475 153.225 1.00 80.72  ? 652 LEU A CB  1 
ATOM   5119 C  CG  . LEU A 1 652 ? 123.800 128.153 153.856 1.00 85.49  ? 652 LEU A CG  1 
ATOM   5120 C  CD1 . LEU A 1 652 ? 122.292 128.065 153.947 1.00 87.00  ? 652 LEU A CD1 1 
ATOM   5121 C  CD2 . LEU A 1 652 ? 124.346 126.999 153.041 1.00 86.85  ? 652 LEU A CD2 1 
ATOM   5122 N  N   . VAL A 1 653 ? 126.080 131.527 154.942 1.00 75.07  ? 653 VAL A N   1 
ATOM   5123 C  CA  . VAL A 1 653 ? 127.025 131.800 156.023 1.00 77.93  ? 653 VAL A CA  1 
ATOM   5124 C  C   . VAL A 1 653 ? 126.448 132.830 156.985 1.00 84.60  ? 653 VAL A C   1 
ATOM   5125 O  O   . VAL A 1 653 ? 126.539 132.678 158.209 1.00 94.11  ? 653 VAL A O   1 
ATOM   5126 C  CB  . VAL A 1 653 ? 128.379 132.256 155.447 1.00 75.56  ? 653 VAL A CB  1 
ATOM   5127 C  CG1 . VAL A 1 653 ? 129.237 132.888 156.529 1.00 77.65  ? 653 VAL A CG1 1 
ATOM   5128 C  CG2 . VAL A 1 653 ? 129.103 131.086 154.807 1.00 81.26  ? 653 VAL A CG2 1 
ATOM   5129 N  N   . ALA A 1 654 ? 125.833 133.888 156.450 1.00 83.66  ? 654 ALA A N   1 
ATOM   5130 C  CA  . ALA A 1 654 ? 125.228 134.907 157.300 1.00 78.57  ? 654 ALA A CA  1 
ATOM   5131 C  C   . ALA A 1 654 ? 124.057 134.351 158.099 1.00 85.16  ? 654 ALA A C   1 
ATOM   5132 O  O   . ALA A 1 654 ? 123.792 134.812 159.214 1.00 95.21  ? 654 ALA A O   1 
ATOM   5133 C  CB  . ALA A 1 654 ? 124.775 136.094 156.453 1.00 82.49  ? 654 ALA A CB  1 
ATOM   5134 N  N   . ARG A 1 655 ? 123.344 133.369 157.545 1.00 90.48  ? 655 ARG A N   1 
ATOM   5135 C  CA  . ARG A 1 655 ? 122.244 132.750 158.277 1.00 92.59  ? 655 ARG A CA  1 
ATOM   5136 C  C   . ARG A 1 655 ? 122.741 132.054 159.539 1.00 96.82  ? 655 ARG A C   1 
ATOM   5137 O  O   . ARG A 1 655 ? 122.107 132.143 160.596 1.00 96.83  ? 655 ARG A O   1 
ATOM   5138 C  CB  . ARG A 1 655 ? 121.508 131.761 157.370 1.00 91.85  ? 655 ARG A CB  1 
ATOM   5139 C  CG  . ARG A 1 655 ? 120.783 130.636 158.096 1.00 94.49  ? 655 ARG A CG  1 
ATOM   5140 C  CD  . ARG A 1 655 ? 119.328 130.980 158.382 1.00 101.29 ? 655 ARG A CD  1 
ATOM   5141 N  NE  . ARG A 1 655 ? 119.190 132.162 159.224 1.00 103.29 ? 655 ARG A NE  1 
ATOM   5142 C  CZ  . ARG A 1 655 ? 118.034 132.734 159.530 1.00 104.46 ? 655 ARG A CZ  1 
ATOM   5143 N  NH1 . ARG A 1 655 ? 116.886 132.259 159.073 1.00 102.89 ? 655 ARG A NH1 1 
ATOM   5144 N  NH2 . ARG A 1 655 ? 118.027 133.808 160.313 1.00 103.50 ? 655 ARG A NH2 1 
ATOM   5145 N  N   . TYR A 1 656 ? 123.874 131.359 159.449 1.00 92.32  ? 656 TYR A N   1 
ATOM   5146 C  CA  . TYR A 1 656 ? 124.426 130.651 160.596 1.00 86.35  ? 656 TYR A CA  1 
ATOM   5147 C  C   . TYR A 1 656 ? 125.182 131.560 161.559 1.00 89.72  ? 656 TYR A C   1 
ATOM   5148 O  O   . TYR A 1 656 ? 125.339 131.194 162.728 1.00 94.44  ? 656 TYR A O   1 
ATOM   5149 C  CB  . TYR A 1 656 ? 125.343 129.524 160.124 1.00 84.62  ? 656 TYR A CB  1 
ATOM   5150 C  CG  . TYR A 1 656 ? 124.587 128.287 159.709 1.00 89.39  ? 656 TYR A CG  1 
ATOM   5151 C  CD1 . TYR A 1 656 ? 124.030 127.446 160.659 1.00 89.40  ? 656 TYR A CD1 1 
ATOM   5152 C  CD2 . TYR A 1 656 ? 124.416 127.968 158.371 1.00 93.94  ? 656 TYR A CD2 1 
ATOM   5153 C  CE1 . TYR A 1 656 ? 123.333 126.319 160.289 1.00 90.70  ? 656 TYR A CE1 1 
ATOM   5154 C  CE2 . TYR A 1 656 ? 123.718 126.843 157.992 1.00 96.57  ? 656 TYR A CE2 1 
ATOM   5155 C  CZ  . TYR A 1 656 ? 123.179 126.021 158.956 1.00 97.17  ? 656 TYR A CZ  1 
ATOM   5156 O  OH  . TYR A 1 656 ? 122.482 124.896 158.588 1.00 104.36 ? 656 TYR A OH  1 
ATOM   5157 N  N   . LEU A 1 657 ? 125.653 132.720 161.106 1.00 89.57  ? 657 LEU A N   1 
ATOM   5158 C  CA  . LEU A 1 657 ? 126.309 133.665 162.001 1.00 86.75  ? 657 LEU A CA  1 
ATOM   5159 C  C   . LEU A 1 657 ? 125.314 134.385 162.901 1.00 92.41  ? 657 LEU A C   1 
ATOM   5160 O  O   . LEU A 1 657 ? 125.608 134.635 164.074 1.00 98.89  ? 657 LEU A O   1 
ATOM   5161 C  CB  . LEU A 1 657 ? 127.111 134.687 161.192 1.00 87.03  ? 657 LEU A CB  1 
ATOM   5162 C  CG  . LEU A 1 657 ? 128.403 134.195 160.538 1.00 82.83  ? 657 LEU A CG  1 
ATOM   5163 C  CD1 . LEU A 1 657 ? 129.212 135.367 160.013 1.00 85.45  ? 657 LEU A CD1 1 
ATOM   5164 C  CD2 . LEU A 1 657 ? 129.224 133.377 161.516 1.00 86.15  ? 657 LEU A CD2 1 
ATOM   5165 N  N   . LYS A 1 658 ? 124.135 134.662 162.369 1.00 97.34  ? 658 LYS A N   1 
ATOM   5166 C  CA  . LYS A 1 658 ? 123.106 135.420 163.117 1.00 100.10 ? 658 LYS A CA  1 
ATOM   5167 C  C   . LYS A 1 658 ? 121.791 134.654 162.986 1.00 103.91 ? 658 LYS A C   1 
ATOM   5168 O  O   . LYS A 1 658 ? 120.949 135.057 162.223 1.00 109.73 ? 658 LYS A O   1 
ATOM   5169 C  CB  . LYS A 1 658 ? 123.038 136.886 162.676 1.00 102.77 ? 658 LYS A CB  1 
ATOM   5170 C  CG  . LYS A 1 658 ? 124.345 137.665 162.642 1.00 99.39  ? 658 LYS A CG  1 
ATOM   5171 C  CD  . LYS A 1 658 ? 124.991 137.864 163.984 1.00 100.07 ? 658 LYS A CD  1 
ATOM   5172 C  CE  . LYS A 1 658 ? 124.878 139.281 164.498 1.00 101.27 ? 658 LYS A CE  1 
ATOM   5173 N  NZ  . LYS A 1 658 ? 126.173 139.997 164.442 1.00 102.05 ? 658 LYS A NZ  1 
ATOM   5174 N  N   . PRO A 1 659 ? 121.617 133.519 163.672 1.00 105.66 ? 659 PRO A N   1 
ATOM   5175 C  CA  . PRO A 1 659 ? 120.398 132.711 163.516 1.00 108.27 ? 659 PRO A CA  1 
ATOM   5176 C  C   . PRO A 1 659 ? 119.157 133.324 164.148 1.00 108.68 ? 659 PRO A C   1 
ATOM   5177 O  O   . PRO A 1 659 ? 118.085 132.714 164.071 1.00 106.24 ? 659 PRO A O   1 
ATOM   5178 C  CB  . PRO A 1 659 ? 120.770 131.391 164.202 1.00 103.91 ? 659 PRO A CB  1 
ATOM   5179 C  CG  . PRO A 1 659 ? 121.792 131.771 165.208 1.00 103.27 ? 659 PRO A CG  1 
ATOM   5180 C  CD  . PRO A 1 659 ? 122.565 132.919 164.627 1.00 101.51 ? 659 PRO A CD  1 
ATOM   5181 N  N   . ASN A 1 660 ? 119.259 134.498 164.767 1.00 114.70 ? 660 ASN A N   1 
ATOM   5182 C  CA  . ASN A 1 660 ? 118.128 135.137 165.425 1.00 114.89 ? 660 ASN A CA  1 
ATOM   5183 C  C   . ASN A 1 660 ? 117.512 136.258 164.596 1.00 115.07 ? 660 ASN A C   1 
ATOM   5184 O  O   . ASN A 1 660 ? 116.675 137.005 165.113 1.00 115.37 ? 660 ASN A O   1 
ATOM   5185 C  CB  . ASN A 1 660 ? 118.556 135.676 166.792 1.00 116.27 ? 660 ASN A CB  1 
ATOM   5186 C  CG  . ASN A 1 660 ? 118.620 134.595 167.849 1.00 117.35 ? 660 ASN A CG  1 
ATOM   5187 O  OD1 . ASN A 1 660 ? 117.917 133.589 167.768 1.00 115.78 ? 660 ASN A OD1 1 
ATOM   5188 N  ND2 . ASN A 1 660 ? 119.467 134.799 168.851 1.00 115.32 ? 660 ASN A ND2 1 
ATOM   5189 N  N   . VAL A 1 661 ? 117.917 136.376 163.342 1.00 110.01 ? 661 VAL A N   1 
ATOM   5190 C  CA  . VAL A 1 661 ? 117.469 137.499 162.487 1.00 110.21 ? 661 VAL A CA  1 
ATOM   5191 C  C   . VAL A 1 661 ? 116.657 136.914 161.332 1.00 113.70 ? 661 VAL A C   1 
ATOM   5192 O  O   . VAL A 1 661 ? 117.180 136.030 160.681 1.00 116.40 ? 661 VAL A O   1 
ATOM   5193 C  CB  . VAL A 1 661 ? 118.685 138.321 162.028 1.00 109.53 ? 661 VAL A CB  1 
ATOM   5194 C  CG1 . VAL A 1 661 ? 118.294 139.507 161.167 1.00 109.82 ? 661 VAL A CG1 1 
ATOM   5195 C  CG2 . VAL A 1 661 ? 119.542 138.771 163.196 1.00 107.88 ? 661 VAL A CG2 1 
ATOM   5196 N  N   . GLN A 1 662 ? 115.426 137.336 161.118 1.00 123.56 ? 662 GLN A N   1 
ATOM   5197 C  CA  . GLN A 1 662 ? 114.738 136.654 160.007 1.00 123.87 ? 662 GLN A CA  1 
ATOM   5198 C  C   . GLN A 1 662 ? 114.960 137.467 158.733 1.00 122.21 ? 662 GLN A C   1 
ATOM   5199 O  O   . GLN A 1 662 ? 115.345 138.626 158.821 1.00 123.94 ? 662 GLN A O   1 
ATOM   5200 C  CB  . GLN A 1 662 ? 113.289 136.385 160.397 1.00 123.97 ? 662 GLN A CB  1 
ATOM   5201 C  CG  . GLN A 1 662 ? 112.998 136.648 161.865 1.00 123.10 ? 662 GLN A CG  1 
ATOM   5202 C  CD  . GLN A 1 662 ? 111.515 136.698 162.130 1.00 128.73 ? 662 GLN A CD  1 
ATOM   5203 O  OE1 . GLN A 1 662 ? 110.697 136.487 161.237 1.00 130.09 ? 662 GLN A OE1 1 
ATOM   5204 N  NE2 . GLN A 1 662 ? 111.153 136.983 163.371 1.00 129.90 ? 662 GLN A NE2 1 
ATOM   5205 N  N   . PHE A 1 663 ? 114.683 136.836 157.607 1.00 111.04 ? 663 PHE A N   1 
ATOM   5206 C  CA  . PHE A 1 663 ? 115.226 137.144 156.292 1.00 113.82 ? 663 PHE A CA  1 
ATOM   5207 C  C   . PHE A 1 663 ? 114.403 138.142 155.486 1.00 117.40 ? 663 PHE A C   1 
ATOM   5208 O  O   . PHE A 1 663 ? 114.845 138.532 154.402 1.00 123.96 ? 663 PHE A O   1 
ATOM   5209 C  CB  . PHE A 1 663 ? 115.388 135.862 155.466 1.00 115.61 ? 663 PHE A CB  1 
ATOM   5210 C  CG  . PHE A 1 663 ? 116.799 135.359 155.402 1.00 115.67 ? 663 PHE A CG  1 
ATOM   5211 C  CD1 . PHE A 1 663 ? 117.473 134.994 156.554 1.00 115.76 ? 663 PHE A CD1 1 
ATOM   5212 C  CD2 . PHE A 1 663 ? 117.459 135.266 154.188 1.00 113.97 ? 663 PHE A CD2 1 
ATOM   5213 C  CE1 . PHE A 1 663 ? 118.773 134.533 156.495 1.00 116.18 ? 663 PHE A CE1 1 
ATOM   5214 C  CE2 . PHE A 1 663 ? 118.758 134.806 154.126 1.00 112.86 ? 663 PHE A CE2 1 
ATOM   5215 C  CZ  . PHE A 1 663 ? 119.416 134.439 155.279 1.00 115.66 ? 663 PHE A CZ  1 
ATOM   5216 N  N   . ASP A 1 664 ? 113.231 138.559 155.970 1.00 115.44 ? 664 ASP A N   1 
ATOM   5217 C  CA  . ASP A 1 664 ? 112.423 139.533 155.241 1.00 115.06 ? 664 ASP A CA  1 
ATOM   5218 C  C   . ASP A 1 664 ? 112.103 139.035 153.833 1.00 117.68 ? 664 ASP A C   1 
ATOM   5219 O  O   . ASP A 1 664 ? 112.646 139.543 152.844 1.00 121.22 ? 664 ASP A O   1 
ATOM   5220 C  CB  . ASP A 1 664 ? 113.118 140.896 155.193 1.00 117.61 ? 664 ASP A CB  1 
ATOM   5221 C  CG  . ASP A 1 664 ? 112.211 141.995 154.679 1.00 123.99 ? 664 ASP A CG  1 
ATOM   5222 O  OD1 . ASP A 1 664 ? 110.985 141.769 154.602 1.00 125.75 ? 664 ASP A OD1 1 
ATOM   5223 O  OD2 . ASP A 1 664 ? 112.720 143.091 154.369 1.00 122.51 ? 664 ASP A OD2 1 
ATOM   5224 N  N   . ASP A 1 665 ? 111.261 138.002 153.749 1.00 124.58 ? 665 ASP A N   1 
ATOM   5225 C  CA  . ASP A 1 665 ? 110.941 137.395 152.461 1.00 126.83 ? 665 ASP A CA  1 
ATOM   5226 C  C   . ASP A 1 665 ? 110.410 138.422 151.468 1.00 126.74 ? 665 ASP A C   1 
ATOM   5227 O  O   . ASP A 1 665 ? 110.599 138.273 150.258 1.00 127.80 ? 665 ASP A O   1 
ATOM   5228 C  CB  . ASP A 1 665 ? 109.926 136.267 152.646 1.00 125.27 ? 665 ASP A CB  1 
ATOM   5229 C  CG  . ASP A 1 665 ? 110.522 135.055 153.327 1.00 129.04 ? 665 ASP A CG  1 
ATOM   5230 O  OD1 . ASP A 1 665 ? 111.765 134.965 153.398 1.00 131.98 ? 665 ASP A OD1 1 
ATOM   5231 O  OD2 . ASP A 1 665 ? 109.747 134.193 153.791 1.00 127.56 ? 665 ASP A OD2 1 
ATOM   5232 N  N   . LYS A 1 666 ? 109.761 139.492 151.894 1.00 115.13 ? 666 LYS A N   1 
ATOM   5233 C  CA  . LYS A 1 666 ? 109.287 140.432 150.843 1.00 114.44 ? 666 LYS A CA  1 
ATOM   5234 C  C   . LYS A 1 666 ? 110.472 141.106 150.189 1.00 113.36 ? 666 LYS A C   1 
ATOM   5235 O  O   . LYS A 1 666 ? 110.465 141.248 148.992 1.00 115.28 ? 666 LYS A O   1 
ATOM   5236 C  CB  . LYS A 1 666 ? 108.414 141.580 151.333 1.00 110.92 ? 666 LYS A CB  1 
ATOM   5237 C  CG  . LYS A 1 666 ? 106.927 141.275 151.420 1.00 112.93 ? 666 LYS A CG  1 
ATOM   5238 C  CD  . LYS A 1 666 ? 106.099 142.485 151.773 1.00 116.85 ? 666 LYS A CD  1 
ATOM   5239 C  CE  . LYS A 1 666 ? 104.620 142.181 151.857 1.00 115.31 ? 666 LYS A CE  1 
ATOM   5240 N  NZ  . LYS A 1 666 ? 103.830 143.392 152.180 1.00 115.93 ? 666 LYS A NZ  1 
ATOM   5241 N  N   . LEU A 1 667 ? 111.509 141.513 150.896 1.00 104.93 ? 667 LEU A N   1 
ATOM   5242 C  CA  . LEU A 1 667 ? 112.717 142.111 150.270 1.00 103.92 ? 667 LEU A CA  1 
ATOM   5243 C  C   . LEU A 1 667 ? 113.533 141.047 149.558 1.00 102.12 ? 667 LEU A C   1 
ATOM   5244 O  O   . LEU A 1 667 ? 114.271 141.378 148.654 1.00 104.11 ? 667 LEU A O   1 
ATOM   5245 C  CB  . LEU A 1 667 ? 113.592 142.736 151.352 1.00 101.37 ? 667 LEU A CB  1 
ATOM   5246 C  CG  . LEU A 1 667 ? 114.965 143.256 150.937 1.00 99.51  ? 667 LEU A CG  1 
ATOM   5247 C  CD1 . LEU A 1 667 ? 114.856 144.642 150.340 1.00 101.65 ? 667 LEU A CD1 1 
ATOM   5248 C  CD2 . LEU A 1 667 ? 115.897 143.279 152.133 1.00 101.29 ? 667 LEU A CD2 1 
ATOM   5249 N  N   . MET A 1 668 ? 113.418 139.811 149.997 1.00 109.18 ? 668 MET A N   1 
ATOM   5250 C  CA  . MET A 1 668 ? 114.214 138.776 149.347 1.00 107.87 ? 668 MET A CA  1 
ATOM   5251 C  C   . MET A 1 668 ? 113.625 138.371 147.998 1.00 111.80 ? 668 MET A C   1 
ATOM   5252 O  O   . MET A 1 668 ? 114.358 138.184 147.021 1.00 115.10 ? 668 MET A O   1 
ATOM   5253 C  CB  . MET A 1 668 ? 114.346 137.567 150.271 1.00 112.57 ? 668 MET A CB  1 
ATOM   5254 C  CG  . MET A 1 668 ? 115.655 136.830 150.117 1.00 115.12 ? 668 MET A CG  1 
ATOM   5255 S  SD  . MET A 1 668 ? 117.100 137.859 150.384 1.00 122.25 ? 668 MET A SD  1 
ATOM   5256 C  CE  . MET A 1 668 ? 117.818 137.848 148.748 1.00 105.86 ? 668 MET A CE  1 
ATOM   5257 N  N   . THR A 1 669 ? 112.290 138.317 147.908 1.00 108.53 ? 669 THR A N   1 
ATOM   5258 C  CA  . THR A 1 669 ? 111.562 137.926 146.680 1.00 108.36 ? 669 THR A CA  1 
ATOM   5259 C  C   . THR A 1 669 ? 111.812 138.993 145.624 1.00 105.32 ? 669 THR A C   1 
ATOM   5260 O  O   . THR A 1 669 ? 112.035 138.666 144.467 1.00 109.27 ? 669 THR A O   1 
ATOM   5261 C  CB  . THR A 1 669 ? 110.047 137.727 146.926 1.00 107.42 ? 669 THR A CB  1 
ATOM   5262 O  OG1 . THR A 1 669 ? 109.458 137.077 145.806 1.00 113.77 ? 669 THR A OG1 1 
ATOM   5263 C  CG2 . THR A 1 669 ? 109.287 139.011 147.160 1.00 104.99 ? 669 THR A CG2 1 
ATOM   5264 N  N   . TRP A 1 670 ? 111.734 140.225 146.072 1.00 98.79  ? 670 TRP A N   1 
ATOM   5265 C  CA  . TRP A 1 670 ? 111.968 141.352 145.182 1.00 101.32 ? 670 TRP A CA  1 
ATOM   5266 C  C   . TRP A 1 670 ? 113.381 141.311 144.623 1.00 103.44 ? 670 TRP A C   1 
ATOM   5267 O  O   . TRP A 1 670 ? 113.578 141.403 143.410 1.00 109.18 ? 670 TRP A O   1 
ATOM   5268 C  CB  . TRP A 1 670 ? 111.714 142.664 145.923 1.00 102.67 ? 670 TRP A CB  1 
ATOM   5269 C  CG  . TRP A 1 670 ? 110.328 143.197 145.746 1.00 105.52 ? 670 TRP A CG  1 
ATOM   5270 C  CD1 . TRP A 1 670 ? 109.344 143.242 146.688 1.00 108.46 ? 670 TRP A CD1 1 
ATOM   5271 C  CD2 . TRP A 1 670 ? 109.775 143.782 144.562 1.00 105.05 ? 670 TRP A CD2 1 
ATOM   5272 N  NE1 . TRP A 1 670 ? 108.209 143.805 146.162 1.00 109.51 ? 670 TRP A NE1 1 
ATOM   5273 C  CE2 . TRP A 1 670 ? 108.449 144.149 144.858 1.00 109.14 ? 670 TRP A CE2 1 
ATOM   5274 C  CE3 . TRP A 1 670 ? 110.271 144.026 143.278 1.00 105.79 ? 670 TRP A CE3 1 
ATOM   5275 C  CZ2 . TRP A 1 670 ? 107.611 144.744 143.917 1.00 110.37 ? 670 TRP A CZ2 1 
ATOM   5276 C  CZ3 . TRP A 1 670 ? 109.440 144.619 142.348 1.00 106.22 ? 670 TRP A CZ3 1 
ATOM   5277 C  CH2 . TRP A 1 670 ? 108.127 144.973 142.672 1.00 107.88 ? 670 TRP A CH2 1 
ATOM   5278 N  N   . GLY A 1 671 ? 114.375 141.130 145.492 1.00 96.96  ? 671 GLY A N   1 
ATOM   5279 C  CA  . GLY A 1 671 ? 115.751 141.100 145.023 1.00 94.70  ? 671 GLY A CA  1 
ATOM   5280 C  C   . GLY A 1 671 ? 116.019 139.958 144.063 1.00 93.20  ? 671 GLY A C   1 
ATOM   5281 O  O   . GLY A 1 671 ? 116.615 140.146 142.998 1.00 105.94 ? 671 GLY A O   1 
ATOM   5282 N  N   . PHE A 1 672 ? 115.560 138.756 144.418 1.00 80.74  ? 672 PHE A N   1 
ATOM   5283 C  CA  . PHE A 1 672 ? 115.809 137.578 143.592 1.00 82.83  ? 672 PHE A CA  1 
ATOM   5284 C  C   . PHE A 1 672 ? 115.174 137.720 142.212 1.00 87.78  ? 672 PHE A C   1 
ATOM   5285 O  O   . PHE A 1 672 ? 115.836 137.528 141.179 1.00 94.85  ? 672 PHE A O   1 
ATOM   5286 C  CB  . PHE A 1 672 ? 115.277 136.338 144.313 1.00 83.45  ? 672 PHE A CB  1 
ATOM   5287 C  CG  . PHE A 1 672 ? 115.459 135.057 143.554 1.00 82.55  ? 672 PHE A CG  1 
ATOM   5288 C  CD1 . PHE A 1 672 ? 114.417 134.514 142.824 1.00 88.47  ? 672 PHE A CD1 1 
ATOM   5289 C  CD2 . PHE A 1 672 ? 116.667 134.383 143.586 1.00 86.88  ? 672 PHE A CD2 1 
ATOM   5290 C  CE1 . PHE A 1 672 ? 114.576 133.336 142.129 1.00 88.29  ? 672 PHE A CE1 1 
ATOM   5291 C  CE2 . PHE A 1 672 ? 116.833 133.201 142.892 1.00 85.83  ? 672 PHE A CE2 1 
ATOM   5292 C  CZ  . PHE A 1 672 ? 115.785 132.677 142.164 1.00 83.06  ? 672 PHE A CZ  1 
ATOM   5293 N  N   . TRP A 1 673 ? 113.886 138.069 142.174 1.00 85.89  ? 673 TRP A N   1 
ATOM   5294 C  CA  . TRP A 1 673 ? 113.197 138.149 140.893 1.00 81.13  ? 673 TRP A CA  1 
ATOM   5295 C  C   . TRP A 1 673 ? 113.672 139.348 140.086 1.00 82.14  ? 673 TRP A C   1 
ATOM   5296 O  O   . TRP A 1 673 ? 113.716 139.288 138.854 1.00 87.36  ? 673 TRP A O   1 
ATOM   5297 C  CB  . TRP A 1 673 ? 111.686 138.191 141.112 1.00 87.48  ? 673 TRP A CB  1 
ATOM   5298 C  CG  . TRP A 1 673 ? 111.126 136.848 141.464 1.00 89.02  ? 673 TRP A CG  1 
ATOM   5299 C  CD1 . TRP A 1 673 ? 110.421 136.525 142.584 1.00 90.97  ? 673 TRP A CD1 1 
ATOM   5300 C  CD2 . TRP A 1 673 ? 111.240 135.641 140.700 1.00 90.96  ? 673 TRP A CD2 1 
ATOM   5301 N  NE1 . TRP A 1 673 ? 110.083 135.194 142.563 1.00 91.91  ? 673 TRP A NE1 1 
ATOM   5302 C  CE2 . TRP A 1 673 ? 110.574 134.630 141.417 1.00 92.73  ? 673 TRP A CE2 1 
ATOM   5303 C  CE3 . TRP A 1 673 ? 111.837 135.318 139.477 1.00 90.67  ? 673 TRP A CE3 1 
ATOM   5304 C  CZ2 . TRP A 1 673 ? 110.487 133.320 140.954 1.00 91.00  ? 673 TRP A CZ2 1 
ATOM   5305 C  CZ3 . TRP A 1 673 ? 111.749 134.016 139.019 1.00 91.80  ? 673 TRP A CZ3 1 
ATOM   5306 C  CH2 . TRP A 1 673 ? 111.080 133.035 139.756 1.00 93.71  ? 673 TRP A CH2 1 
ATOM   5307 N  N   . LEU A 1 674 ? 114.151 140.427 140.682 1.00 82.35  ? 674 LEU A N   1 
ATOM   5308 C  CA  . LEU A 1 674 ? 114.681 141.607 139.962 1.00 79.18  ? 674 LEU A CA  1 
ATOM   5309 C  C   . LEU A 1 674 ? 116.041 141.268 139.372 1.00 81.29  ? 674 LEU A C   1 
ATOM   5310 O  O   . LEU A 1 674 ? 116.391 141.796 138.337 1.00 90.77  ? 674 LEU A O   1 
ATOM   5311 C  CB  . LEU A 1 674 ? 114.793 142.833 140.863 1.00 78.12  ? 674 LEU A CB  1 
ATOM   5312 C  CG  . LEU A 1 674 ? 113.550 143.685 141.098 1.00 83.67  ? 674 LEU A CG  1 
ATOM   5313 C  CD1 . LEU A 1 674 ? 113.762 144.584 142.307 1.00 86.90  ? 674 LEU A CD1 1 
ATOM   5314 C  CD2 . LEU A 1 674 ? 113.226 144.519 139.877 1.00 84.49  ? 674 LEU A CD2 1 
ATOM   5315 N  N   . LEU A 1 675 ? 116.787 140.457 140.082 1.00 77.82  ? 675 LEU A N   1 
ATOM   5316 C  CA  . LEU A 1 675 ? 118.044 140.016 139.485 1.00 74.71  ? 675 LEU A CA  1 
ATOM   5317 C  C   . LEU A 1 675 ? 117.797 139.129 138.271 1.00 83.96  ? 675 LEU A C   1 
ATOM   5318 O  O   . LEU A 1 675 ? 118.370 139.349 137.193 1.00 93.33  ? 675 LEU A O   1 
ATOM   5319 C  CB  . LEU A 1 675 ? 118.884 139.275 140.525 1.00 72.73  ? 675 LEU A CB  1 
ATOM   5320 C  CG  . LEU A 1 675 ? 119.723 140.129 141.474 1.00 78.66  ? 675 LEU A CG  1 
ATOM   5321 C  CD1 . LEU A 1 675 ? 120.287 139.274 142.593 1.00 78.31  ? 675 LEU A CD1 1 
ATOM   5322 C  CD2 . LEU A 1 675 ? 120.836 140.830 140.722 1.00 79.51  ? 675 LEU A CD2 1 
ATOM   5323 N  N   . ASN A 1 676 ? 117.007 138.078 138.408 1.00 87.18  ? 676 ASN A N   1 
ATOM   5324 C  CA  . ASN A 1 676 ? 116.709 137.132 137.300 1.00 85.25  ? 676 ASN A CA  1 
ATOM   5325 C  C   . ASN A 1 676 ? 116.025 137.866 136.131 1.00 87.54  ? 676 ASN A C   1 
ATOM   5326 O  O   . ASN A 1 676 ? 116.452 137.614 135.019 1.00 85.77  ? 676 ASN A O   1 
ATOM   5327 C  CB  . ASN A 1 676 ? 116.007 135.860 137.804 1.00 83.67  ? 676 ASN A CB  1 
ATOM   5328 C  CG  . ASN A 1 676 ? 116.905 134.865 138.510 1.00 86.54  ? 676 ASN A CG  1 
ATOM   5329 O  OD1 . ASN A 1 676 ? 116.775 134.633 139.709 1.00 88.10  ? 676 ASN A OD1 1 
ATOM   5330 N  ND2 . ASN A 1 676 ? 117.816 134.260 137.777 1.00 90.35  ? 676 ASN A ND2 1 
ATOM   5331 N  N   . GLY A 1 677 ? 115.059 138.774 136.373 1.00 87.78  ? 677 GLY A N   1 
ATOM   5332 C  CA  . GLY A 1 677 ? 114.406 139.483 135.286 1.00 84.18  ? 677 GLY A CA  1 
ATOM   5333 C  C   . GLY A 1 677 ? 115.320 140.482 134.610 1.00 85.83  ? 677 GLY A C   1 
ATOM   5334 O  O   . GLY A 1 677 ? 115.268 140.660 133.394 1.00 94.44  ? 677 GLY A O   1 
ATOM   5335 N  N   . GLY A 1 678 ? 116.172 141.152 135.390 1.00 85.40  ? 678 GLY A N   1 
ATOM   5336 C  CA  . GLY A 1 678 ? 117.113 142.084 134.801 1.00 86.64  ? 678 GLY A CA  1 
ATOM   5337 C  C   . GLY A 1 678 ? 118.118 141.395 133.904 1.00 94.31  ? 678 GLY A C   1 
ATOM   5338 O  O   . GLY A 1 678 ? 118.423 141.873 132.810 1.00 104.84 ? 678 GLY A O   1 
ATOM   5339 N  N   . LEU A 1 679 ? 118.642 140.250 134.349 1.00 78.08  ? 679 LEU A N   1 
ATOM   5340 C  CA  . LEU A 1 679 ? 119.561 139.500 133.499 1.00 80.12  ? 679 LEU A CA  1 
ATOM   5341 C  C   . LEU A 1 679 ? 118.866 139.041 132.219 1.00 84.67  ? 679 LEU A C   1 
ATOM   5342 O  O   . LEU A 1 679 ? 119.399 139.204 131.111 1.00 88.68  ? 679 LEU A O   1 
ATOM   5343 C  CB  . LEU A 1 679 ? 120.134 138.308 134.268 1.00 74.90  ? 679 LEU A CB  1 
ATOM   5344 C  CG  . LEU A 1 679 ? 121.160 137.449 133.527 1.00 76.74  ? 679 LEU A CG  1 
ATOM   5345 C  CD1 . LEU A 1 679 ? 122.281 138.310 132.971 1.00 83.36  ? 679 LEU A CD1 1 
ATOM   5346 C  CD2 . LEU A 1 679 ? 121.717 136.376 134.446 1.00 80.59  ? 679 LEU A CD2 1 
ATOM   5347 N  N   . VAL A 1 680 ? 117.652 138.499 132.353 1.00 85.83  ? 680 VAL A N   1 
ATOM   5348 C  CA  . VAL A 1 680 ? 116.921 138.016 131.184 1.00 83.24  ? 680 VAL A CA  1 
ATOM   5349 C  C   . VAL A 1 680 ? 116.652 139.155 130.210 1.00 84.05  ? 680 VAL A C   1 
ATOM   5350 O  O   . VAL A 1 680 ? 116.845 139.010 128.997 1.00 89.39  ? 680 VAL A O   1 
ATOM   5351 C  CB  . VAL A 1 680 ? 115.616 137.322 131.614 1.00 79.84  ? 680 VAL A CB  1 
ATOM   5352 C  CG1 . VAL A 1 680 ? 114.649 137.230 130.445 1.00 80.91  ? 680 VAL A CG1 1 
ATOM   5353 C  CG2 . VAL A 1 680 ? 115.907 135.942 132.168 1.00 79.16  ? 680 VAL A CG2 1 
ATOM   5354 N  N   . GLY A 1 681 ? 116.200 140.302 130.719 1.00 86.19  ? 681 GLY A N   1 
ATOM   5355 C  CA  . GLY A 1 681 ? 115.905 141.425 129.844 1.00 86.98  ? 681 GLY A CA  1 
ATOM   5356 C  C   . GLY A 1 681 ? 117.140 141.979 129.165 1.00 91.82  ? 681 GLY A C   1 
ATOM   5357 O  O   . GLY A 1 681 ? 117.145 142.212 127.955 1.00 100.42 ? 681 GLY A O   1 
ATOM   5358 N  N   . MET A 1 682 ? 118.236 142.127 129.860 1.00 85.13  ? 682 MET A N   1 
ATOM   5359 C  CA  . MET A 1 682 ? 119.453 142.727 129.273 1.00 85.66  ? 682 MET A CA  1 
ATOM   5360 C  C   . MET A 1 682 ? 119.989 141.780 128.201 1.00 88.41  ? 682 MET A C   1 
ATOM   5361 O  O   . MET A 1 682 ? 120.492 142.244 127.198 1.00 93.45  ? 682 MET A O   1 
ATOM   5362 C  CB  . MET A 1 682 ? 120.535 142.967 130.320 1.00 80.61  ? 682 MET A CB  1 
ATOM   5363 C  CG  . MET A 1 682 ? 121.636 141.939 130.318 1.00 89.19  ? 682 MET A CG  1 
ATOM   5364 S  SD  . MET A 1 682 ? 122.844 142.150 131.646 1.00 108.02 ? 682 MET A SD  1 
ATOM   5365 C  CE  . MET A 1 682 ? 122.023 143.360 132.685 1.00 89.61  ? 682 MET A CE  1 
ATOM   5366 N  N   . ILE A 1 683 ? 119.811 140.490 128.229 1.00 83.20  ? 683 ILE A N   1 
ATOM   5367 C  CA  . ILE A 1 683 ? 120.287 139.683 127.102 1.00 85.14  ? 683 ILE A CA  1 
ATOM   5368 C  C   . ILE A 1 683 ? 119.227 139.727 126.020 1.00 85.50  ? 683 ILE A C   1 
ATOM   5369 O  O   . ILE A 1 683 ? 119.533 140.143 124.916 1.00 91.70  ? 683 ILE A O   1 
ATOM   5370 C  CB  . ILE A 1 683 ? 120.528 138.237 127.569 1.00 83.76  ? 683 ILE A CB  1 
ATOM   5371 C  CG1 . ILE A 1 683 ? 121.824 138.090 128.372 1.00 82.04  ? 683 ILE A CG1 1 
ATOM   5372 C  CG2 . ILE A 1 683 ? 120.447 137.263 126.395 1.00 79.81  ? 683 ILE A CG2 1 
ATOM   5373 C  CD1 . ILE A 1 683 ? 121.779 137.006 129.417 1.00 90.98  ? 683 ILE A CD1 1 
ATOM   5374 N  N   . ALA A 1 684 ? 117.978 139.546 126.406 1.00 88.09  ? 684 ALA A N   1 
ATOM   5375 C  CA  . ALA A 1 684 ? 117.023 139.283 125.339 1.00 90.80  ? 684 ALA A CA  1 
ATOM   5376 C  C   . ALA A 1 684 ? 116.615 140.512 124.540 1.00 92.44  ? 684 ALA A C   1 
ATOM   5377 O  O   . ALA A 1 684 ? 116.283 140.371 123.359 1.00 101.85 ? 684 ALA A O   1 
ATOM   5378 C  CB  . ALA A 1 684 ? 115.759 138.630 125.912 1.00 93.76  ? 684 ALA A CB  1 
ATOM   5379 N  N   . ILE A 1 685 ? 116.652 141.713 125.114 1.00 92.18  ? 685 ILE A N   1 
ATOM   5380 C  CA  . ILE A 1 685 ? 116.125 142.914 124.403 1.00 96.45  ? 685 ILE A CA  1 
ATOM   5381 C  C   . ILE A 1 685 ? 117.267 143.793 123.884 1.00 96.22  ? 685 ILE A C   1 
ATOM   5382 O  O   . ILE A 1 685 ? 116.993 144.627 123.050 1.00 103.90 ? 685 ILE A O   1 
ATOM   5383 C  CB  . ILE A 1 685 ? 115.065 143.725 125.204 1.00 97.60  ? 685 ILE A CB  1 
ATOM   5384 C  CG1 . ILE A 1 685 ? 115.534 144.141 126.601 1.00 93.94  ? 685 ILE A CG1 1 
ATOM   5385 C  CG2 . ILE A 1 685 ? 113.745 142.973 125.258 1.00 99.09  ? 685 ILE A CG2 1 
ATOM   5386 C  CD1 . ILE A 1 685 ? 116.219 145.474 126.667 1.00 93.84  ? 685 ILE A CD1 1 
ATOM   5387 N  N   . SER A 1 686 ? 118.463 143.654 124.407 1.00 91.77  ? 686 SER A N   1 
ATOM   5388 C  CA  . SER A 1 686 ? 119.556 144.516 123.912 1.00 97.49  ? 686 SER A CA  1 
ATOM   5389 C  C   . SER A 1 686 ? 120.716 143.665 123.419 1.00 94.78  ? 686 SER A C   1 
ATOM   5390 O  O   . SER A 1 686 ? 121.099 143.803 122.275 1.00 98.54  ? 686 SER A O   1 
ATOM   5391 C  CB  . SER A 1 686 ? 120.038 145.418 124.971 1.00 98.94  ? 686 SER A CB  1 
ATOM   5392 O  OG  . SER A 1 686 ? 121.175 146.143 124.538 1.00 96.74  ? 686 SER A OG  1 
ATOM   5393 N  N   . LEU A 1 687 ? 121.241 142.815 124.268 1.00 83.08  ? 687 LEU A N   1 
ATOM   5394 C  CA  . LEU A 1 687 ? 122.535 142.218 123.966 1.00 86.43  ? 687 LEU A CA  1 
ATOM   5395 C  C   . LEU A 1 687 ? 122.446 141.197 122.835 1.00 85.57  ? 687 LEU A C   1 
ATOM   5396 O  O   . LEU A 1 687 ? 123.287 141.187 121.932 1.00 84.33  ? 687 LEU A O   1 
ATOM   5397 C  CB  . LEU A 1 687 ? 123.118 141.576 125.226 1.00 85.77  ? 687 LEU A CB  1 
ATOM   5398 C  CG  . LEU A 1 687 ? 124.094 142.420 126.045 1.00 84.88  ? 687 LEU A CG  1 
ATOM   5399 C  CD1 . LEU A 1 687 ? 124.389 141.750 127.377 1.00 81.71  ? 687 LEU A CD1 1 
ATOM   5400 C  CD2 . LEU A 1 687 ? 125.376 142.673 125.274 1.00 86.06  ? 687 LEU A CD2 1 
ATOM   5401 N  N   . LEU A 1 688 ? 121.441 140.321 122.877 1.00 78.70  ? 688 LEU A N   1 
ATOM   5402 C  CA  . LEU A 1 688 ? 121.299 139.308 121.833 1.00 76.55  ? 688 LEU A CA  1 
ATOM   5403 C  C   . LEU A 1 688 ? 121.005 139.894 120.457 1.00 80.60  ? 688 LEU A C   1 
ATOM   5404 O  O   . LEU A 1 688 ? 121.649 139.466 119.485 1.00 84.24  ? 688 LEU A O   1 
ATOM   5405 C  CB  . LEU A 1 688 ? 120.230 138.289 122.240 1.00 76.27  ? 688 LEU A CB  1 
ATOM   5406 C  CG  . LEU A 1 688 ? 120.216 136.965 121.473 1.00 74.74  ? 688 LEU A CG  1 
ATOM   5407 C  CD1 . LEU A 1 688 ? 121.624 136.420 121.295 1.00 69.46  ? 688 LEU A CD1 1 
ATOM   5408 C  CD2 . LEU A 1 688 ? 119.331 135.951 122.171 1.00 79.50  ? 688 LEU A CD2 1 
ATOM   5409 N  N   . PRO A 1 689 ? 120.049 140.817 120.278 1.00 77.51  ? 689 PRO A N   1 
ATOM   5410 C  CA  . PRO A 1 689 ? 119.826 141.358 118.922 1.00 76.85  ? 689 PRO A CA  1 
ATOM   5411 C  C   . PRO A 1 689 ? 121.051 142.038 118.335 1.00 78.29  ? 689 PRO A C   1 
ATOM   5412 O  O   . PRO A 1 689 ? 121.330 141.893 117.137 1.00 87.22  ? 689 PRO A O   1 
ATOM   5413 C  CB  . PRO A 1 689 ? 118.662 142.338 119.127 1.00 77.67  ? 689 PRO A CB  1 
ATOM   5414 C  CG  . PRO A 1 689 ? 117.991 141.881 120.363 1.00 81.19  ? 689 PRO A CG  1 
ATOM   5415 C  CD  . PRO A 1 689 ? 119.083 141.376 121.241 1.00 79.83  ? 689 PRO A CD  1 
ATOM   5416 N  N   . VAL A 1 690 ? 121.799 142.772 119.161 1.00 77.86  ? 690 VAL A N   1 
ATOM   5417 C  CA  . VAL A 1 690 ? 123.020 143.418 118.686 1.00 78.19  ? 690 VAL A CA  1 
ATOM   5418 C  C   . VAL A 1 690 ? 124.018 142.369 118.220 1.00 78.10  ? 690 VAL A C   1 
ATOM   5419 O  O   . VAL A 1 690 ? 124.635 142.498 117.158 1.00 83.71  ? 690 VAL A O   1 
ATOM   5420 C  CB  . VAL A 1 690 ? 123.614 144.317 119.785 1.00 76.93  ? 690 VAL A CB  1 
ATOM   5421 C  CG1 . VAL A 1 690 ? 125.071 144.630 119.487 1.00 77.32  ? 690 VAL A CG1 1 
ATOM   5422 C  CG2 . VAL A 1 690 ? 122.811 145.597 119.916 1.00 82.54  ? 690 VAL A CG2 1 
ATOM   5423 N  N   . GLY A 1 691 ? 124.180 141.306 119.010 1.00 72.71  ? 691 GLY A N   1 
ATOM   5424 C  CA  . GLY A 1 691 ? 125.096 140.246 118.630 1.00 75.65  ? 691 GLY A CA  1 
ATOM   5425 C  C   . GLY A 1 691 ? 124.686 139.544 117.350 1.00 75.64  ? 691 GLY A C   1 
ATOM   5426 O  O   . GLY A 1 691 ? 125.533 139.200 116.528 1.00 81.55  ? 691 GLY A O   1 
ATOM   5427 N  N   . VAL A 1 692 ? 123.383 139.326 117.163 1.00 67.45  ? 692 VAL A N   1 
ATOM   5428 C  CA  . VAL A 1 692 ? 122.908 138.647 115.960 1.00 66.88  ? 692 VAL A CA  1 
ATOM   5429 C  C   . VAL A 1 692 ? 123.138 139.517 114.728 1.00 68.34  ? 692 VAL A C   1 
ATOM   5430 O  O   . VAL A 1 692 ? 123.592 139.038 113.678 1.00 74.83  ? 692 VAL A O   1 
ATOM   5431 C  CB  . VAL A 1 692 ? 121.426 138.259 116.114 1.00 67.95  ? 692 VAL A CB  1 
ATOM   5432 C  CG1 . VAL A 1 692 ? 120.787 138.012 114.758 1.00 72.68  ? 692 VAL A CG1 1 
ATOM   5433 C  CG2 . VAL A 1 692 ? 121.292 137.035 117.002 1.00 69.96  ? 692 VAL A CG2 1 
ATOM   5434 N  N   . ILE A 1 693 ? 122.831 140.812 114.838 1.00 67.50  ? 693 ILE A N   1 
ATOM   5435 C  CA  . ILE A 1 693 ? 123.054 141.727 113.720 1.00 66.01  ? 693 ILE A CA  1 
ATOM   5436 C  C   . ILE A 1 693 ? 124.541 141.805 113.390 1.00 73.19  ? 693 ILE A C   1 
ATOM   5437 O  O   . ILE A 1 693 ? 124.942 141.785 112.219 1.00 77.62  ? 693 ILE A O   1 
ATOM   5438 C  CB  . ILE A 1 693 ? 122.466 143.113 114.042 1.00 66.64  ? 693 ILE A CB  1 
ATOM   5439 C  CG1 . ILE A 1 693 ? 120.944 143.031 114.135 1.00 72.45  ? 693 ILE A CG1 1 
ATOM   5440 C  CG2 . ILE A 1 693 ? 122.870 144.126 112.990 1.00 68.67  ? 693 ILE A CG2 1 
ATOM   5441 C  CD1 . ILE A 1 693 ? 120.292 144.301 114.620 1.00 73.81  ? 693 ILE A CD1 1 
ATOM   5442 N  N   . GLN A 1 694 ? 125.380 141.884 114.425 1.00 75.69  ? 694 GLN A N   1 
ATOM   5443 C  CA  . GLN A 1 694 ? 126.823 141.915 114.221 1.00 72.82  ? 694 GLN A CA  1 
ATOM   5444 C  C   . GLN A 1 694 ? 127.323 140.629 113.577 1.00 81.70  ? 694 GLN A C   1 
ATOM   5445 O  O   . GLN A 1 694 ? 128.213 140.661 112.725 1.00 88.69  ? 694 GLN A O   1 
ATOM   5446 C  CB  . GLN A 1 694 ? 127.529 142.155 115.552 1.00 69.95  ? 694 GLN A CB  1 
ATOM   5447 C  CG  . GLN A 1 694 ? 128.202 143.503 115.669 1.00 75.87  ? 694 GLN A CG  1 
ATOM   5448 C  CD  . GLN A 1 694 ? 128.878 143.688 117.006 1.00 84.47  ? 694 GLN A CD  1 
ATOM   5449 O  OE1 . GLN A 1 694 ? 128.871 142.788 117.842 1.00 85.62  ? 694 GLN A OE1 1 
ATOM   5450 N  NE2 . GLN A 1 694 ? 129.482 144.850 117.210 1.00 86.55  ? 694 GLN A NE2 1 
ATOM   5451 N  N   . ALA A 1 695 ? 126.777 139.484 113.989 1.00 71.46  ? 695 ALA A N   1 
ATOM   5452 C  CA  . ALA A 1 695 ? 127.179 138.208 113.407 1.00 62.89  ? 695 ALA A CA  1 
ATOM   5453 C  C   . ALA A 1 695 ? 126.823 138.144 111.929 1.00 64.50  ? 695 ALA A C   1 
ATOM   5454 O  O   . ALA A 1 695 ? 127.623 137.691 111.101 1.00 75.77  ? 695 ALA A O   1 
ATOM   5455 C  CB  . ALA A 1 695 ? 126.519 137.059 114.166 1.00 64.83  ? 695 ALA A CB  1 
ATOM   5456 N  N   . TYR A 1 696 ? 125.613 138.589 111.581 1.00 64.55  ? 696 TYR A N   1 
ATOM   5457 C  CA  . TYR A 1 696 ? 125.223 138.608 110.176 1.00 69.75  ? 696 TYR A CA  1 
ATOM   5458 C  C   . TYR A 1 696 ? 126.140 139.521 109.371 1.00 73.59  ? 696 TYR A C   1 
ATOM   5459 O  O   . TYR A 1 696 ? 126.597 139.153 108.280 1.00 77.36  ? 696 TYR A O   1 
ATOM   5460 C  CB  . TYR A 1 696 ? 123.769 139.054 110.034 1.00 77.71  ? 696 TYR A CB  1 
ATOM   5461 C  CG  . TYR A 1 696 ? 123.340 139.238 108.599 1.00 81.36  ? 696 TYR A CG  1 
ATOM   5462 C  CD1 . TYR A 1 696 ? 122.974 138.150 107.822 1.00 81.13  ? 696 TYR A CD1 1 
ATOM   5463 C  CD2 . TYR A 1 696 ? 123.319 140.497 108.013 1.00 81.68  ? 696 TYR A CD2 1 
ATOM   5464 C  CE1 . TYR A 1 696 ? 122.586 138.309 106.510 1.00 81.17  ? 696 TYR A CE1 1 
ATOM   5465 C  CE2 . TYR A 1 696 ? 122.936 140.665 106.700 1.00 84.51  ? 696 TYR A CE2 1 
ATOM   5466 C  CZ  . TYR A 1 696 ? 122.570 139.567 105.953 1.00 87.02  ? 696 TYR A CZ  1 
ATOM   5467 O  OH  . TYR A 1 696 ? 122.187 139.727 104.644 1.00 84.96  ? 696 TYR A OH  1 
ATOM   5468 N  N   . ALA A 1 697 ? 126.427 140.713 109.901 1.00 70.95  ? 697 ALA A N   1 
ATOM   5469 C  CA  . ALA A 1 697 ? 127.308 141.638 109.198 1.00 66.68  ? 697 ALA A CA  1 
ATOM   5470 C  C   . ALA A 1 697 ? 128.706 141.057 109.038 1.00 71.89  ? 697 ALA A C   1 
ATOM   5471 O  O   . ALA A 1 697 ? 129.330 141.212 107.983 1.00 79.14  ? 697 ALA A O   1 
ATOM   5472 C  CB  . ALA A 1 697 ? 127.368 142.972 109.936 1.00 67.23  ? 697 ALA A CB  1 
ATOM   5473 N  N   . SER A 1 698 ? 129.215 140.394 110.075 1.00 73.65  ? 698 SER A N   1 
ATOM   5474 C  CA  . SER A 1 698 ? 130.540 139.791 109.991 1.00 68.48  ? 698 SER A CA  1 
ATOM   5475 C  C   . SER A 1 698 ? 130.576 138.719 108.914 1.00 74.97  ? 698 SER A C   1 
ATOM   5476 O  O   . SER A 1 698 ? 131.399 138.788 107.998 1.00 78.84  ? 698 SER A O   1 
ATOM   5477 C  CB  . SER A 1 698 ? 130.944 139.214 111.346 1.00 64.29  ? 698 SER A CB  1 
ATOM   5478 O  OG  . SER A 1 698 ? 131.892 138.175 111.190 1.00 75.96  ? 698 SER A OG  1 
ATOM   5479 N  N   . ILE A 1 699 ? 129.635 137.773 108.967 1.00 70.26  ? 699 ILE A N   1 
ATOM   5480 C  CA  . ILE A 1 699 ? 129.591 136.694 107.984 1.00 64.55  ? 699 ILE A CA  1 
ATOM   5481 C  C   . ILE A 1 699 ? 129.481 137.247 106.570 1.00 66.84  ? 699 ILE A C   1 
ATOM   5482 O  O   . ILE A 1 699 ? 130.138 136.749 105.649 1.00 71.82  ? 699 ILE A O   1 
ATOM   5483 C  CB  . ILE A 1 699 ? 128.428 135.734 108.306 1.00 66.16  ? 699 ILE A CB  1 
ATOM   5484 C  CG1 . ILE A 1 699 ? 128.707 134.974 109.601 1.00 66.74  ? 699 ILE A CG1 1 
ATOM   5485 C  CG2 . ILE A 1 699 ? 128.201 134.759 107.163 1.00 64.64  ? 699 ILE A CG2 1 
ATOM   5486 C  CD1 . ILE A 1 699 ? 127.545 134.140 110.076 1.00 69.65  ? 699 ILE A CD1 1 
ATOM   5487 N  N   . THR A 1 700 ? 128.667 138.283 106.370 1.00 71.93  ? 700 THR A N   1 
ATOM   5488 C  CA  . THR A 1 700 ? 128.450 138.811 105.030 1.00 73.48  ? 700 THR A CA  1 
ATOM   5489 C  C   . THR A 1 700 ? 129.607 139.660 104.510 1.00 78.55  ? 700 THR A C   1 
ATOM   5490 O  O   . THR A 1 700 ? 129.920 139.579 103.316 1.00 78.47  ? 700 THR A O   1 
ATOM   5491 C  CB  . THR A 1 700 ? 127.159 139.632 104.996 1.00 80.33  ? 700 THR A CB  1 
ATOM   5492 O  OG1 . THR A 1 700 ? 126.085 138.842 105.518 1.00 85.31  ? 700 THR A OG1 1 
ATOM   5493 C  CG2 . THR A 1 700 ? 126.819 140.032 103.573 1.00 86.11  ? 700 THR A CG2 1 
ATOM   5494 N  N   . HIS A 1 701 ? 130.306 140.435 105.321 1.00 80.86  ? 701 HIS A N   1 
ATOM   5495 C  CA  . HIS A 1 701 ? 131.303 141.412 104.813 1.00 77.43  ? 701 HIS A CA  1 
ATOM   5496 C  C   . HIS A 1 701 ? 132.693 141.278 105.422 1.00 75.86  ? 701 HIS A C   1 
ATOM   5497 O  O   . HIS A 1 701 ? 133.634 141.558 104.740 1.00 82.42  ? 701 HIS A O   1 
ATOM   5498 C  CB  . HIS A 1 701 ? 130.806 142.834 105.105 1.00 83.68  ? 701 HIS A CB  1 
ATOM   5499 C  CG  . HIS A 1 701 ? 129.479 143.177 104.510 1.00 89.19  ? 701 HIS A CG  1 
ATOM   5500 N  ND1 . HIS A 1 701 ? 128.297 143.077 105.189 1.00 83.28  ? 701 HIS A ND1 1 
ATOM   5501 C  CD2 . HIS A 1 701 ? 129.186 143.619 103.258 1.00 90.76  ? 701 HIS A CD2 1 
ATOM   5502 C  CE1 . HIS A 1 701 ? 127.305 143.442 104.387 1.00 85.08  ? 701 HIS A CE1 1 
ATOM   5503 N  NE2 . HIS A 1 701 ? 127.833 143.784 103.185 1.00 94.46  ? 701 HIS A NE2 1 
ATOM   5504 N  N   . GLY A 1 702 ? 132.789 140.936 106.687 1.00 73.75  ? 702 GLY A N   1 
ATOM   5505 C  CA  . GLY A 1 702 ? 134.082 140.962 107.345 1.00 77.31  ? 702 GLY A CA  1 
ATOM   5506 C  C   . GLY A 1 702 ? 133.946 141.444 108.777 1.00 83.54  ? 702 GLY A C   1 
ATOM   5507 O  O   . GLY A 1 702 ? 133.066 142.237 109.122 1.00 95.99  ? 702 GLY A O   1 
ATOM   5508 N  N   . LEU A 1 703 ? 134.804 140.945 109.621 1.00 72.62  ? 703 LEU A N   1 
ATOM   5509 C  CA  . LEU A 1 703 ? 134.819 141.398 111.024 1.00 75.02  ? 703 LEU A CA  1 
ATOM   5510 C  C   . LEU A 1 703 ? 135.171 142.884 111.094 1.00 83.66  ? 703 LEU A C   1 
ATOM   5511 O  O   . LEU A 1 703 ? 134.665 143.527 111.979 1.00 87.82  ? 703 LEU A O   1 
ATOM   5512 C  CB  . LEU A 1 703 ? 135.770 140.528 111.847 1.00 75.63  ? 703 LEU A CB  1 
ATOM   5513 C  CG  . LEU A 1 703 ? 135.851 140.907 113.319 1.00 80.26  ? 703 LEU A CG  1 
ATOM   5514 C  CD1 . LEU A 1 703 ? 134.676 140.324 114.074 1.00 80.98  ? 703 LEU A CD1 1 
ATOM   5515 C  CD2 . LEU A 1 703 ? 137.162 140.460 113.919 1.00 81.21  ? 703 LEU A CD2 1 
ATOM   5516 N  N   . TRP A 1 704 ? 135.986 143.380 110.199 1.00 81.32  ? 704 TRP A N   1 
ATOM   5517 C  CA  . TRP A 1 704 ? 136.233 144.819 110.116 1.00 76.53  ? 704 TRP A CA  1 
ATOM   5518 C  C   . TRP A 1 704 ? 134.896 145.552 110.035 1.00 82.98  ? 704 TRP A C   1 
ATOM   5519 O  O   . TRP A 1 704 ? 134.725 146.478 110.770 1.00 93.33  ? 704 TRP A O   1 
ATOM   5520 C  CB  . TRP A 1 704 ? 137.140 145.095 108.921 1.00 70.93  ? 704 TRP A CB  1 
ATOM   5521 C  CG  . TRP A 1 704 ? 136.488 144.950 107.588 1.00 76.73  ? 704 TRP A CG  1 
ATOM   5522 C  CD1 . TRP A 1 704 ? 136.433 143.831 106.815 1.00 84.41  ? 704 TRP A CD1 1 
ATOM   5523 C  CD2 . TRP A 1 704 ? 135.797 145.979 106.867 1.00 79.27  ? 704 TRP A CD2 1 
ATOM   5524 N  NE1 . TRP A 1 704 ? 135.744 144.093 105.665 1.00 85.19  ? 704 TRP A NE1 1 
ATOM   5525 C  CE2 . TRP A 1 704 ? 135.339 145.398 105.670 1.00 85.50  ? 704 TRP A CE2 1 
ATOM   5526 C  CE3 . TRP A 1 704 ? 135.508 147.320 107.124 1.00 79.17  ? 704 TRP A CE3 1 
ATOM   5527 C  CZ2 . TRP A 1 704 ? 134.613 146.118 104.728 1.00 85.65  ? 704 TRP A CZ2 1 
ATOM   5528 C  CZ3 . TRP A 1 704 ? 134.791 148.029 106.193 1.00 82.23  ? 704 TRP A CZ3 1 
ATOM   5529 C  CH2 . TRP A 1 704 ? 134.356 147.436 105.012 1.00 84.12  ? 704 TRP A CH2 1 
ATOM   5530 N  N   . TYR A 1 705 ? 134.043 145.188 109.093 1.00 77.92  ? 705 TYR A N   1 
ATOM   5531 C  CA  . TYR A 1 705 ? 132.758 145.856 108.938 1.00 76.32  ? 705 TYR A CA  1 
ATOM   5532 C  C   . TYR A 1 705 ? 131.889 145.655 110.170 1.00 73.97  ? 705 TYR A C   1 
ATOM   5533 O  O   . TYR A 1 705 ? 131.193 146.578 110.607 1.00 80.43  ? 705 TYR A O   1 
ATOM   5534 C  CB  . TYR A 1 705 ? 132.039 145.344 107.693 1.00 77.24  ? 705 TYR A CB  1 
ATOM   5535 C  CG  . TYR A 1 705 ? 130.778 146.109 107.383 1.00 77.40  ? 705 TYR A CG  1 
ATOM   5536 C  CD1 . TYR A 1 705 ? 130.809 147.478 107.176 1.00 80.88  ? 705 TYR A CD1 1 
ATOM   5537 C  CD2 . TYR A 1 705 ? 129.551 145.464 107.323 1.00 76.02  ? 705 TYR A CD2 1 
ATOM   5538 C  CE1 . TYR A 1 705 ? 129.656 148.184 106.899 1.00 83.39  ? 705 TYR A CE1 1 
ATOM   5539 C  CE2 . TYR A 1 705 ? 128.394 146.160 107.047 1.00 80.62  ? 705 TYR A CE2 1 
ATOM   5540 C  CZ  . TYR A 1 705 ? 128.452 147.519 106.836 1.00 85.94  ? 705 TYR A CZ  1 
ATOM   5541 O  OH  . TYR A 1 705 ? 127.300 148.217 106.561 1.00 91.25  ? 705 TYR A OH  1 
ATOM   5542 N  N   . ALA A 1 706 ? 131.799 144.488 110.769 1.00 63.11  ? 706 ALA A N   1 
ATOM   5543 C  CA  . ALA A 1 706 ? 130.973 144.324 111.976 1.00 65.37  ? 706 ALA A CA  1 
ATOM   5544 C  C   . ALA A 1 706 ? 131.513 145.109 113.190 1.00 64.99  ? 706 ALA A C   1 
ATOM   5545 O  O   . ALA A 1 706 ? 130.721 145.403 114.072 1.00 73.23  ? 706 ALA A O   1 
ATOM   5546 C  CB  . ALA A 1 706 ? 130.790 142.865 112.238 1.00 73.05  ? 706 ALA A CB  1 
ATOM   5547 N  N   . ARG A 1 707 ? 132.800 145.425 113.209 1.00 66.09  ? 707 ARG A N   1 
ATOM   5548 C  CA  . ARG A 1 707 ? 133.288 146.250 114.306 1.00 70.63  ? 707 ARG A CA  1 
ATOM   5549 C  C   . ARG A 1 707 ? 133.470 147.718 113.938 1.00 74.59  ? 707 ARG A C   1 
ATOM   5550 O  O   . ARG A 1 707 ? 133.865 148.509 114.799 1.00 69.25  ? 707 ARG A O   1 
ATOM   5551 C  CB  . ARG A 1 707 ? 134.617 145.695 114.834 1.00 69.07  ? 707 ARG A CB  1 
ATOM   5552 C  CG  . ARG A 1 707 ? 134.550 144.263 115.335 1.00 62.64  ? 707 ARG A CG  1 
ATOM   5553 C  CD  . ARG A 1 707 ? 133.999 144.190 116.745 1.00 64.79  ? 707 ARG A CD  1 
ATOM   5554 N  NE  . ARG A 1 707 ? 134.785 144.980 117.684 1.00 66.25  ? 707 ARG A NE  1 
ATOM   5555 C  CZ  . ARG A 1 707 ? 135.600 144.469 118.596 1.00 72.10  ? 707 ARG A CZ  1 
ATOM   5556 N  NH1 . ARG A 1 707 ? 135.780 143.165 118.709 1.00 75.09  ? 707 ARG A NH1 1 
ATOM   5557 N  NH2 . ARG A 1 707 ? 136.252 145.289 119.415 1.00 74.54  ? 707 ARG A NH2 1 
ATOM   5558 N  N   . SER A 1 708 ? 133.204 148.101 112.691 1.00 87.13  ? 708 SER A N   1 
ATOM   5559 C  CA  . SER A 1 708 ? 133.446 149.470 112.259 1.00 81.50  ? 708 SER A CA  1 
ATOM   5560 C  C   . SER A 1 708 ? 132.546 150.466 112.985 1.00 89.76  ? 708 SER A C   1 
ATOM   5561 O  O   . SER A 1 708 ? 131.446 150.138 113.443 1.00 99.85  ? 708 SER A O   1 
ATOM   5562 C  CB  . SER A 1 708 ? 133.239 149.594 110.751 1.00 84.72  ? 708 SER A CB  1 
ATOM   5563 O  OG  . SER A 1 708 ? 132.078 148.899 110.337 1.00 90.59  ? 708 SER A OG  1 
ATOM   5564 N  N   . GLU A 1 709 ? 133.039 151.704 113.081 1.00 97.18  ? 709 GLU A N   1 
ATOM   5565 C  CA  . GLU A 1 709 ? 132.264 152.782 113.685 1.00 100.66 ? 709 GLU A CA  1 
ATOM   5566 C  C   . GLU A 1 709 ? 130.990 153.055 112.902 1.00 102.74 ? 709 GLU A C   1 
ATOM   5567 O  O   . GLU A 1 709 ? 129.923 153.263 113.490 1.00 107.23 ? 709 GLU A O   1 
ATOM   5568 C  CB  . GLU A 1 709 ? 133.117 154.047 113.769 1.00 97.02  ? 709 GLU A CB  1 
ATOM   5569 C  CG  . GLU A 1 709 ? 132.327 155.324 113.977 1.00 103.51 ? 709 GLU A CG  1 
ATOM   5570 C  CD  . GLU A 1 709 ? 133.170 156.565 113.770 1.00 105.85 ? 709 GLU A CD  1 
ATOM   5571 O  OE1 . GLU A 1 709 ? 134.358 156.423 113.423 1.00 105.96 ? 709 GLU A OE1 1 
ATOM   5572 O  OE2 . GLU A 1 709 ? 132.645 157.681 113.955 1.00 106.95 ? 709 GLU A OE2 1 
ATOM   5573 N  N   . GLU A 1 710 ? 131.083 153.063 111.570 1.00 94.23  ? 710 GLU A N   1 
ATOM   5574 C  CA  . GLU A 1 710 ? 129.911 153.317 110.743 1.00 94.94  ? 710 GLU A CA  1 
ATOM   5575 C  C   . GLU A 1 710 ? 128.822 152.280 110.965 1.00 97.84  ? 710 GLU A C   1 
ATOM   5576 O  O   . GLU A 1 710 ? 127.636 152.628 110.949 1.00 101.58 ? 710 GLU A O   1 
ATOM   5577 C  CB  . GLU A 1 710 ? 130.302 153.353 109.264 1.00 102.41 ? 710 GLU A CB  1 
ATOM   5578 C  CG  . GLU A 1 710 ? 131.307 154.440 108.893 1.00 107.09 ? 710 GLU A CG  1 
ATOM   5579 C  CD  . GLU A 1 710 ? 132.733 154.098 109.285 1.00 113.63 ? 710 GLU A CD  1 
ATOM   5580 O  OE1 . GLU A 1 710 ? 133.563 155.027 109.378 1.00 112.96 ? 710 GLU A OE1 1 
ATOM   5581 O  OE2 . GLU A 1 710 ? 133.025 152.903 109.498 1.00 113.53 ? 710 GLU A OE2 1 
ATOM   5582 N  N   . PHE A 1 711 ? 129.192 151.020 111.179 1.00 85.94  ? 711 PHE A N   1 
ATOM   5583 C  CA  . PHE A 1 711 ? 128.206 149.988 111.462 1.00 83.96  ? 711 PHE A CA  1 
ATOM   5584 C  C   . PHE A 1 711 ? 127.685 150.066 112.892 1.00 88.15  ? 711 PHE A C   1 
ATOM   5585 O  O   . PHE A 1 711 ? 126.488 149.864 113.122 1.00 96.04  ? 711 PHE A O   1 
ATOM   5586 C  CB  . PHE A 1 711 ? 128.801 148.602 111.196 1.00 83.70  ? 711 PHE A CB  1 
ATOM   5587 C  CG  . PHE A 1 711 ? 127.860 147.475 111.492 1.00 85.64  ? 711 PHE A CG  1 
ATOM   5588 C  CD1 . PHE A 1 711 ? 126.894 147.107 110.575 1.00 84.69  ? 711 PHE A CD1 1 
ATOM   5589 C  CD2 . PHE A 1 711 ? 127.937 146.783 112.688 1.00 88.82  ? 711 PHE A CD2 1 
ATOM   5590 C  CE1 . PHE A 1 711 ? 126.024 146.074 110.845 1.00 85.46  ? 711 PHE A CE1 1 
ATOM   5591 C  CE2 . PHE A 1 711 ? 127.069 145.750 112.963 1.00 90.17  ? 711 PHE A CE2 1 
ATOM   5592 C  CZ  . PHE A 1 711 ? 126.111 145.397 112.042 1.00 86.23  ? 711 PHE A CZ  1 
ATOM   5593 N  N   . LEU A 1 712 ? 128.452 150.385 113.923 1.00 85.75  ? 712 LEU A N   1 
ATOM   5594 C  CA  . LEU A 1 712 ? 128.025 150.441 115.351 1.00 82.91  ? 712 LEU A CA  1 
ATOM   5595 C  C   . LEU A 1 712 ? 127.190 151.681 115.662 1.00 86.86  ? 712 LEU A C   1 
ATOM   5596 O  O   . LEU A 1 712 ? 126.481 151.685 116.644 1.00 88.97  ? 712 LEU A O   1 
ATOM   5597 C  CB  . LEU A 1 712 ? 129.244 150.419 116.275 1.00 84.79  ? 712 LEU A CB  1 
ATOM   5598 C  CG  . LEU A 1 712 ? 129.445 149.156 117.104 1.00 84.50  ? 712 LEU A CG  1 
ATOM   5599 C  CD1 . LEU A 1 712 ? 130.326 148.163 116.363 1.00 90.62  ? 712 LEU A CD1 1 
ATOM   5600 C  CD2 . LEU A 1 712 ? 130.039 149.492 118.462 1.00 86.23  ? 712 LEU A CD2 1 
ATOM   5601 N  N   . GLN A 1 713 ? 127.223 152.643 114.760 1.00 90.40  ? 713 GLN A N   1 
ATOM   5602 C  CA  . GLN A 1 713 ? 126.518 153.910 115.000 1.00 86.04  ? 713 GLN A CA  1 
ATOM   5603 C  C   . GLN A 1 713 ? 125.252 153.912 114.162 1.00 89.02  ? 713 GLN A C   1 
ATOM   5604 O  O   . GLN A 1 713 ? 124.700 154.974 113.972 1.00 92.00  ? 713 GLN A O   1 
ATOM   5605 C  CB  . GLN A 1 713 ? 127.459 155.083 114.747 1.00 85.77  ? 713 GLN A CB  1 
ATOM   5606 C  CG  . GLN A 1 713 ? 128.664 155.128 115.666 1.00 90.37  ? 713 GLN A CG  1 
ATOM   5607 C  CD  . GLN A 1 713 ? 128.254 155.277 117.104 1.00 93.12  ? 713 GLN A CD  1 
ATOM   5608 O  OE1 . GLN A 1 713 ? 128.741 154.577 117.983 1.00 95.10  ? 713 GLN A OE1 1 
ATOM   5609 N  NE2 . GLN A 1 713 ? 127.340 156.195 117.352 1.00 94.38  ? 713 GLN A NE2 1 
ATOM   5610 N  N   . MET A 1 714 ? 124.815 152.751 113.688 1.00 98.64  ? 714 MET A N   1 
ATOM   5611 C  CA  . MET A 1 714 ? 123.531 152.678 113.010 1.00 100.58 ? 714 MET A CA  1 
ATOM   5612 C  C   . MET A 1 714 ? 122.411 153.030 113.980 1.00 106.40 ? 714 MET A C   1 
ATOM   5613 O  O   . MET A 1 714 ? 122.549 152.874 115.196 1.00 107.42 ? 714 MET A O   1 
ATOM   5614 C  CB  . MET A 1 714 ? 123.308 151.282 112.429 1.00 101.82 ? 714 MET A CB  1 
ATOM   5615 C  CG  . MET A 1 714 ? 123.784 151.124 110.996 1.00 102.00 ? 714 MET A CG  1 
ATOM   5616 S  SD  . MET A 1 714 ? 123.594 149.444 110.367 1.00 115.02 ? 714 MET A SD  1 
ATOM   5617 C  CE  . MET A 1 714 ? 123.685 148.493 111.880 1.00 108.92 ? 714 MET A CE  1 
ATOM   5618 N  N   . GLU A 1 715 ? 121.298 153.518 113.431 1.00 114.73 ? 715 GLU A N   1 
ATOM   5619 C  CA  . GLU A 1 715 ? 120.190 153.966 114.271 1.00 115.46 ? 715 GLU A CA  1 
ATOM   5620 C  C   . GLU A 1 715 ? 119.619 152.816 115.094 1.00 116.53 ? 715 GLU A C   1 
ATOM   5621 O  O   . GLU A 1 715 ? 119.288 152.985 116.272 1.00 117.78 ? 715 GLU A O   1 
ATOM   5622 C  CB  . GLU A 1 715 ? 119.108 154.603 113.405 1.00 113.58 ? 715 GLU A CB  1 
ATOM   5623 C  CG  . GLU A 1 715 ? 118.199 155.561 114.150 1.00 119.75 ? 715 GLU A CG  1 
ATOM   5624 C  CD  . GLU A 1 715 ? 116.747 155.428 113.738 1.00 125.30 ? 715 GLU A CD  1 
ATOM   5625 O  OE1 . GLU A 1 715 ? 115.880 155.326 114.631 1.00 122.00 ? 715 GLU A OE1 1 
ATOM   5626 O  OE2 . GLU A 1 715 ? 116.474 155.427 112.519 1.00 127.53 ? 715 GLU A OE2 1 
ATOM   5627 N  N   . ILE A 1 716 ? 119.495 151.634 114.486 1.00 107.84 ? 716 ILE A N   1 
ATOM   5628 C  CA  . ILE A 1 716 ? 118.944 150.486 115.199 1.00 109.09 ? 716 ILE A CA  1 
ATOM   5629 C  C   . ILE A 1 716 ? 119.891 150.044 116.309 1.00 110.40 ? 716 ILE A C   1 
ATOM   5630 O  O   . ILE A 1 716 ? 119.459 149.639 117.394 1.00 117.63 ? 716 ILE A O   1 
ATOM   5631 C  CB  . ILE A 1 716 ? 118.634 149.339 114.216 1.00 105.70 ? 716 ILE A CB  1 
ATOM   5632 C  CG1 . ILE A 1 716 ? 117.994 148.156 114.945 1.00 113.70 ? 716 ILE A CG1 1 
ATOM   5633 C  CG2 . ILE A 1 716 ? 119.885 148.909 113.460 1.00 104.15 ? 716 ILE A CG2 1 
ATOM   5634 C  CD1 . ILE A 1 716 ? 116.802 148.531 115.795 1.00 112.42 ? 716 ILE A CD1 1 
ATOM   5635 N  N   . LEU A 1 717 ? 121.200 150.085 116.128 1.00 100.25 ? 717 LEU A N   1 
ATOM   5636 C  CA  . LEU A 1 717 ? 122.183 149.632 117.146 1.00 97.46  ? 717 LEU A CA  1 
ATOM   5637 C  C   . LEU A 1 717 ? 122.345 150.687 118.243 1.00 95.13  ? 717 LEU A C   1 
ATOM   5638 O  O   . LEU A 1 717 ? 122.691 150.298 119.334 1.00 100.16 ? 717 LEU A O   1 
ATOM   5639 C  CB  . LEU A 1 717 ? 123.535 149.326 116.470 1.00 98.76  ? 717 LEU A CB  1 
ATOM   5640 C  CG  . LEU A 1 717 ? 123.625 148.063 115.615 1.00 97.68  ? 717 LEU A CG  1 
ATOM   5641 C  CD1 . LEU A 1 717 ? 125.078 147.729 115.316 1.00 93.06  ? 717 LEU A CD1 1 
ATOM   5642 C  CD2 . LEU A 1 717 ? 122.928 146.882 116.279 1.00 102.34 ? 717 LEU A CD2 1 
ATOM   5643 N  N   . ASP A 1 718 ? 122.188 151.973 118.026 1.00 89.63  ? 718 ASP A N   1 
ATOM   5644 C  CA  . ASP A 1 718 ? 122.222 152.952 119.138 1.00 92.18  ? 718 ASP A CA  1 
ATOM   5645 C  C   . ASP A 1 718 ? 120.923 152.864 119.957 1.00 99.96  ? 718 ASP A C   1 
ATOM   5646 O  O   . ASP A 1 718 ? 121.035 152.958 121.179 1.00 101.99 ? 718 ASP A O   1 
ATOM   5647 C  CB  . ASP A 1 718 ? 122.538 154.353 118.606 1.00 95.75  ? 718 ASP A CB  1 
ATOM   5648 C  CG  . ASP A 1 718 ? 122.567 155.445 119.660 1.00 101.85 ? 718 ASP A CG  1 
ATOM   5649 O  OD1 . ASP A 1 718 ? 123.473 155.419 120.518 1.00 101.21 ? 718 ASP A OD1 1 
ATOM   5650 O  OD2 . ASP A 1 718 ? 121.697 156.323 119.600 1.00 104.81 ? 718 ASP A OD2 1 
ATOM   5651 N  N   . THR A 1 719 ? 119.755 152.667 119.326 1.00 100.57 ? 719 THR A N   1 
ATOM   5652 C  CA  . THR A 1 719 ? 118.562 152.517 120.147 1.00 98.37  ? 719 THR A CA  1 
ATOM   5653 C  C   . THR A 1 719 ? 118.504 151.168 120.850 1.00 99.08  ? 719 THR A C   1 
ATOM   5654 O  O   . THR A 1 719 ? 117.778 151.039 121.840 1.00 103.82 ? 719 THR A O   1 
ATOM   5655 C  CB  . THR A 1 719 ? 117.304 152.717 119.296 1.00 98.99  ? 719 THR A CB  1 
ATOM   5656 O  OG1 . THR A 1 719 ? 116.204 153.069 120.144 1.00 109.03 ? 719 THR A OG1 1 
ATOM   5657 C  CG2 . THR A 1 719 ? 116.953 151.453 118.536 1.00 98.76  ? 719 THR A CG2 1 
ATOM   5658 N  N   . LEU A 1 720 ? 119.252 150.174 120.377 1.00 95.15  ? 720 LEU A N   1 
ATOM   5659 C  CA  . LEU A 1 720 ? 119.256 148.854 120.988 1.00 91.17  ? 720 LEU A CA  1 
ATOM   5660 C  C   . LEU A 1 720 ? 120.062 148.800 122.276 1.00 91.86  ? 720 LEU A C   1 
ATOM   5661 O  O   . LEU A 1 720 ? 119.745 147.988 123.149 1.00 95.26  ? 720 LEU A O   1 
ATOM   5662 C  CB  . LEU A 1 720 ? 119.801 147.821 119.998 1.00 93.23  ? 720 LEU A CB  1 
ATOM   5663 C  CG  . LEU A 1 720 ? 119.029 146.512 119.852 1.00 92.07  ? 720 LEU A CG  1 
ATOM   5664 C  CD1 . LEU A 1 720 ? 117.536 146.756 119.924 1.00 92.44  ? 720 LEU A CD1 1 
ATOM   5665 C  CD2 . LEU A 1 720 ? 119.397 145.850 118.541 1.00 94.91  ? 720 LEU A CD2 1 
ATOM   5666 N  N   . ARG A 1 721 ? 121.080 149.672 122.356 1.00 87.06  ? 721 ARG A N   1 
ATOM   5667 C  CA  . ARG A 1 721 ? 122.030 149.871 123.484 1.00 88.87  ? 721 ARG A CA  1 
ATOM   5668 C  C   . ARG A 1 721 ? 121.463 150.786 124.565 1.00 92.95  ? 721 ARG A C   1 
ATOM   5669 O  O   . ARG A 1 721 ? 121.817 150.611 125.709 1.00 101.28 ? 721 ARG A O   1 
ATOM   5670 C  CB  . ARG A 1 721 ? 123.280 150.532 122.912 1.00 86.59  ? 721 ARG A CB  1 
ATOM   5671 C  CG  . ARG A 1 721 ? 124.493 149.624 122.759 1.00 89.58  ? 721 ARG A CG  1 
ATOM   5672 C  CD  . ARG A 1 721 ? 125.826 150.279 122.429 1.00 86.78  ? 721 ARG A CD  1 
ATOM   5673 N  NE  . ARG A 1 721 ? 125.811 151.469 121.591 1.00 91.65  ? 721 ARG A NE  1 
ATOM   5674 C  CZ  . ARG A 1 721 ? 125.946 151.508 120.265 1.00 94.85  ? 721 ARG A CZ  1 
ATOM   5675 N  NH1 . ARG A 1 721 ? 125.841 152.656 119.627 1.00 90.61  ? 721 ARG A NH1 1 
ATOM   5676 N  NH2 . ARG A 1 721 ? 126.188 150.411 119.571 1.00 95.60  ? 721 ARG A NH2 1 
ATOM   5677 N  N   . TRP A 1 722 ? 120.684 151.808 124.204 1.00 98.97  ? 722 TRP A N   1 
ATOM   5678 C  CA  . TRP A 1 722 ? 119.963 152.719 125.121 1.00 99.00  ? 722 TRP A CA  1 
ATOM   5679 C  C   . TRP A 1 722 ? 118.852 151.964 125.845 1.00 102.91 ? 722 TRP A C   1 
ATOM   5680 O  O   . TRP A 1 722 ? 118.675 152.196 127.016 1.00 102.93 ? 722 TRP A O   1 
ATOM   5681 C  CB  . TRP A 1 722 ? 119.339 153.881 124.352 1.00 94.93  ? 722 TRP A CB  1 
ATOM   5682 C  CG  . TRP A 1 722 ? 120.149 155.135 124.249 1.00 103.98 ? 722 TRP A CG  1 
ATOM   5683 C  CD1 . TRP A 1 722 ? 120.805 155.598 123.148 1.00 108.04 ? 722 TRP A CD1 1 
ATOM   5684 C  CD2 . TRP A 1 722 ? 120.359 156.110 125.281 1.00 109.33 ? 722 TRP A CD2 1 
ATOM   5685 N  NE1 . TRP A 1 722 ? 121.428 156.780 123.426 1.00 110.43 ? 722 TRP A NE1 1 
ATOM   5686 C  CE2 . TRP A 1 722 ? 121.174 157.120 124.726 1.00 113.80 ? 722 TRP A CE2 1 
ATOM   5687 C  CE3 . TRP A 1 722 ? 119.959 156.216 126.617 1.00 104.24 ? 722 TRP A CE3 1 
ATOM   5688 C  CZ2 . TRP A 1 722 ? 121.591 158.226 125.467 1.00 108.85 ? 722 TRP A CZ2 1 
ATOM   5689 C  CZ3 . TRP A 1 722 ? 120.372 157.307 127.346 1.00 108.63 ? 722 TRP A CZ3 1 
ATOM   5690 C  CH2 . TRP A 1 722 ? 121.175 158.295 126.776 1.00 108.59 ? 722 TRP A CH2 1 
ATOM   5691 N  N   . VAL A 1 723 ? 118.149 151.098 125.144 1.00 96.81  ? 723 VAL A N   1 
ATOM   5692 C  CA  . VAL A 1 723 ? 117.078 150.326 125.759 1.00 89.33  ? 723 VAL A CA  1 
ATOM   5693 C  C   . VAL A 1 723 ? 117.615 149.428 126.867 1.00 89.82  ? 723 VAL A C   1 
ATOM   5694 O  O   . VAL A 1 723 ? 116.883 149.097 127.807 1.00 98.29  ? 723 VAL A O   1 
ATOM   5695 C  CB  . VAL A 1 723 ? 116.338 149.532 124.655 1.00 91.68  ? 723 VAL A CB  1 
ATOM   5696 C  CG1 . VAL A 1 723 ? 115.592 148.343 125.219 1.00 94.02  ? 723 VAL A CG1 1 
ATOM   5697 C  CG2 . VAL A 1 723 ? 115.380 150.441 123.906 1.00 93.36  ? 723 VAL A CG2 1 
ATOM   5698 N  N   . ARG A 1 724 ? 118.850 148.950 126.785 1.00 86.25  ? 724 ARG A N   1 
ATOM   5699 C  CA  . ARG A 1 724 ? 119.514 148.160 127.855 1.00 84.82  ? 724 ARG A CA  1 
ATOM   5700 C  C   . ARG A 1 724 ? 119.390 148.816 129.230 1.00 94.23  ? 724 ARG A C   1 
ATOM   5701 O  O   . ARG A 1 724 ? 119.343 148.075 130.188 1.00 103.72 ? 724 ARG A O   1 
ATOM   5702 C  CB  . ARG A 1 724 ? 121.000 147.924 127.541 1.00 86.31  ? 724 ARG A CB  1 
ATOM   5703 C  CG  . ARG A 1 724 ? 121.629 146.694 128.184 1.00 89.18  ? 724 ARG A CG  1 
ATOM   5704 C  CD  . ARG A 1 724 ? 123.111 146.801 128.513 1.00 89.97  ? 724 ARG A CD  1 
ATOM   5705 N  NE  . ARG A 1 724 ? 123.616 145.788 129.438 1.00 98.50  ? 724 ARG A NE  1 
ATOM   5706 C  CZ  . ARG A 1 724 ? 124.817 145.219 129.376 1.00 97.87  ? 724 ARG A CZ  1 
ATOM   5707 N  NH1 . ARG A 1 724 ? 125.680 145.611 128.461 1.00 97.81  ? 724 ARG A NH1 1 
ATOM   5708 N  NH2 . ARG A 1 724 ? 125.147 144.251 130.214 1.00 93.63  ? 724 ARG A NH2 1 
ATOM   5709 N  N   . THR A 1 725 ? 119.337 150.141 129.307 1.00 98.47  ? 725 THR A N   1 
ATOM   5710 C  CA  . THR A 1 725 ? 119.339 150.806 130.607 1.00 98.59  ? 725 THR A CA  1 
ATOM   5711 C  C   . THR A 1 725 ? 118.132 150.406 131.448 1.00 99.44  ? 725 THR A C   1 
ATOM   5712 O  O   . THR A 1 725 ? 118.215 150.358 132.680 1.00 100.52 ? 725 THR A O   1 
ATOM   5713 C  CB  . THR A 1 725 ? 119.375 152.322 130.418 1.00 99.01  ? 725 THR A CB  1 
ATOM   5714 O  OG1 . THR A 1 725 ? 118.211 152.742 129.699 1.00 109.57 ? 725 THR A OG1 1 
ATOM   5715 C  CG2 . THR A 1 725 ? 120.610 152.728 129.638 1.00 93.31  ? 725 THR A CG2 1 
ATOM   5716 N  N   . ALA A 1 726 ? 117.003 150.114 130.799 1.00 100.83 ? 726 ALA A N   1 
ATOM   5717 C  CA  . ALA A 1 726 ? 115.809 149.717 131.537 1.00 97.91  ? 726 ALA A CA  1 
ATOM   5718 C  C   . ALA A 1 726 ? 116.028 148.422 132.310 1.00 99.53  ? 726 ALA A C   1 
ATOM   5719 O  O   . ALA A 1 726 ? 115.614 148.315 133.469 1.00 108.70 ? 726 ALA A O   1 
ATOM   5720 C  CB  . ALA A 1 726 ? 114.625 149.574 130.586 1.00 99.11  ? 726 ALA A CB  1 
ATOM   5721 N  N   . ALA A 1 727 ? 116.669 147.433 131.690 1.00 93.86  ? 727 ALA A N   1 
ATOM   5722 C  CA  . ALA A 1 727 ? 116.991 146.188 132.375 1.00 98.69  ? 727 ALA A CA  1 
ATOM   5723 C  C   . ALA A 1 727 ? 118.170 146.350 133.324 1.00 99.33  ? 727 ALA A C   1 
ATOM   5724 O  O   . ALA A 1 727 ? 118.235 145.673 134.359 1.00 105.79 ? 727 ALA A O   1 
ATOM   5725 C  CB  . ALA A 1 727 ? 117.287 145.087 131.355 1.00 93.35  ? 727 ALA A CB  1 
ATOM   5726 N  N   . ASP A 1 728 ? 119.105 147.241 132.987 1.00 96.18  ? 728 ASP A N   1 
ATOM   5727 C  CA  . ASP A 1 728 ? 120.234 147.494 133.873 1.00 96.79  ? 728 ASP A CA  1 
ATOM   5728 C  C   . ASP A 1 728 ? 119.772 148.066 135.204 1.00 103.70 ? 728 ASP A C   1 
ATOM   5729 O  O   . ASP A 1 728 ? 120.281 147.683 136.261 1.00 112.80 ? 728 ASP A O   1 
ATOM   5730 C  CB  . ASP A 1 728 ? 121.229 148.442 133.207 1.00 100.29 ? 728 ASP A CB  1 
ATOM   5731 C  CG  . ASP A 1 728 ? 121.854 147.848 131.966 1.00 114.49 ? 728 ASP A CG  1 
ATOM   5732 O  OD1 . ASP A 1 728 ? 121.994 148.579 130.964 1.00 115.86 ? 728 ASP A OD1 1 
ATOM   5733 O  OD2 . ASP A 1 728 ? 122.191 146.646 131.986 1.00 120.70 ? 728 ASP A OD2 1 
ATOM   5734 N  N   . LEU A 1 729 ? 118.805 148.986 135.172 1.00 96.85  ? 729 LEU A N   1 
ATOM   5735 C  CA  . LEU A 1 729 ? 118.282 149.559 136.407 1.00 94.04  ? 729 LEU A CA  1 
ATOM   5736 C  C   . LEU A 1 729 ? 117.610 148.493 137.264 1.00 95.39  ? 729 LEU A C   1 
ATOM   5737 O  O   . LEU A 1 729 ? 117.750 148.485 138.492 1.00 101.87 ? 729 LEU A O   1 
ATOM   5738 C  CB  . LEU A 1 729 ? 117.305 150.689 136.083 1.00 92.20  ? 729 LEU A CB  1 
ATOM   5739 C  CG  . LEU A 1 729 ? 117.917 152.044 135.722 1.00 101.16 ? 729 LEU A CG  1 
ATOM   5740 C  CD1 . LEU A 1 729 ? 116.923 153.159 135.983 1.00 99.52  ? 729 LEU A CD1 1 
ATOM   5741 C  CD2 . LEU A 1 729 ? 119.204 152.281 136.496 1.00 100.43 ? 729 LEU A CD2 1 
ATOM   5742 N  N   . ILE A 1 730 ? 116.869 147.585 136.628 1.00 80.38  ? 730 ILE A N   1 
ATOM   5743 C  CA  . ILE A 1 730 ? 116.217 146.501 137.358 1.00 81.33  ? 730 ILE A CA  1 
ATOM   5744 C  C   . ILE A 1 730 ? 117.254 145.600 138.016 1.00 85.38  ? 730 ILE A C   1 
ATOM   5745 O  O   . ILE A 1 730 ? 117.113 145.210 139.185 1.00 94.77  ? 730 ILE A O   1 
ATOM   5746 C  CB  . ILE A 1 730 ? 115.292 145.716 136.407 1.00 81.06  ? 730 ILE A CB  1 
ATOM   5747 C  CG1 . ILE A 1 730 ? 113.978 146.472 136.206 1.00 88.28  ? 730 ILE A CG1 1 
ATOM   5748 C  CG2 . ILE A 1 730 ? 115.029 144.320 136.932 1.00 87.50  ? 730 ILE A CG2 1 
ATOM   5749 C  CD1 . ILE A 1 730 ? 113.280 146.150 134.907 1.00 86.50  ? 730 ILE A CD1 1 
ATOM   5750 N  N   . PHE A 1 731 ? 118.318 145.264 137.283 1.00 75.20  ? 731 PHE A N   1 
ATOM   5751 C  CA  . PHE A 1 731 ? 119.384 144.446 137.856 1.00 76.40  ? 731 PHE A CA  1 
ATOM   5752 C  C   . PHE A 1 731 ? 120.067 145.157 139.020 1.00 84.37  ? 731 PHE A C   1 
ATOM   5753 O  O   . PHE A 1 731 ? 120.377 144.533 140.043 1.00 92.60  ? 731 PHE A O   1 
ATOM   5754 C  CB  . PHE A 1 731 ? 120.400 144.078 136.776 1.00 73.49  ? 731 PHE A CB  1 
ATOM   5755 C  CG  . PHE A 1 731 ? 121.286 142.925 137.146 1.00 76.11  ? 731 PHE A CG  1 
ATOM   5756 C  CD1 . PHE A 1 731 ? 122.481 143.138 137.808 1.00 77.58  ? 731 PHE A CD1 1 
ATOM   5757 C  CD2 . PHE A 1 731 ? 120.922 141.628 136.834 1.00 82.97  ? 731 PHE A CD2 1 
ATOM   5758 C  CE1 . PHE A 1 731 ? 123.297 142.082 138.150 1.00 80.00  ? 731 PHE A CE1 1 
ATOM   5759 C  CE2 . PHE A 1 731 ? 121.736 140.567 137.174 1.00 83.76  ? 731 PHE A CE2 1 
ATOM   5760 C  CZ  . PHE A 1 731 ? 122.924 140.795 137.832 1.00 81.02  ? 731 PHE A CZ  1 
ATOM   5761 N  N   . ILE A 1 732 ? 120.312 146.441 138.885 1.00 83.25  ? 732 ILE A N   1 
ATOM   5762 C  CA  . ILE A 1 732 ? 120.971 147.177 139.987 1.00 79.35  ? 732 ILE A CA  1 
ATOM   5763 C  C   . ILE A 1 732 ? 120.029 147.215 141.186 1.00 87.58  ? 732 ILE A C   1 
ATOM   5764 O  O   . ILE A 1 732 ? 120.524 147.058 142.271 1.00 94.43  ? 732 ILE A O   1 
ATOM   5765 C  CB  . ILE A 1 732 ? 121.446 148.565 139.529 1.00 73.31  ? 732 ILE A CB  1 
ATOM   5766 C  CG1 . ILE A 1 732 ? 122.440 148.445 138.372 1.00 79.54  ? 732 ILE A CG1 1 
ATOM   5767 C  CG2 . ILE A 1 732 ? 122.019 149.360 140.687 1.00 77.98  ? 732 ILE A CG2 1 
ATOM   5768 C  CD1 . ILE A 1 732 ? 122.826 149.749 137.737 1.00 88.54  ? 732 ILE A CD1 1 
ATOM   5769 N  N   . GLY A 1 733 ? 118.730 147.388 140.993 1.00 83.01  ? 733 GLY A N   1 
ATOM   5770 C  CA  . GLY A 1 733 ? 117.809 147.348 142.119 1.00 80.51  ? 733 GLY A CA  1 
ATOM   5771 C  C   . GLY A 1 733 ? 117.815 146.007 142.825 1.00 82.23  ? 733 GLY A C   1 
ATOM   5772 O  O   . GLY A 1 733 ? 117.803 145.938 144.057 1.00 94.05  ? 733 GLY A O   1 
ATOM   5773 N  N   . GLY A 1 734 ? 117.831 144.919 142.051 1.00 69.80  ? 734 GLY A N   1 
ATOM   5774 C  CA  . GLY A 1 734 ? 117.896 143.599 142.663 1.00 75.55  ? 734 GLY A CA  1 
ATOM   5775 C  C   . GLY A 1 734 ? 119.171 143.388 143.455 1.00 84.69  ? 734 GLY A C   1 
ATOM   5776 O  O   . GLY A 1 734 ? 119.154 142.841 144.565 1.00 94.76  ? 734 GLY A O   1 
ATOM   5777 N  N   . ALA A 1 735 ? 120.303 143.825 142.893 1.00 77.67  ? 735 ALA A N   1 
ATOM   5778 C  CA  . ALA A 1 735 ? 121.573 143.712 143.601 1.00 72.55  ? 735 ALA A CA  1 
ATOM   5779 C  C   . ALA A 1 735 ? 121.559 144.514 144.895 1.00 79.67  ? 735 ALA A C   1 
ATOM   5780 O  O   . ALA A 1 735 ? 122.051 144.049 145.931 1.00 86.80  ? 735 ALA A O   1 
ATOM   5781 C  CB  . ALA A 1 735 ? 122.717 144.170 142.696 1.00 69.55  ? 735 ALA A CB  1 
ATOM   5782 N  N   . ILE A 1 736 ? 120.994 145.723 144.854 1.00 85.17  ? 736 ILE A N   1 
ATOM   5783 C  CA  . ILE A 1 736 ? 120.922 146.554 146.051 1.00 84.50  ? 736 ILE A CA  1 
ATOM   5784 C  C   . ILE A 1 736 ? 120.040 145.896 147.102 1.00 87.24  ? 736 ILE A C   1 
ATOM   5785 O  O   . ILE A 1 736 ? 120.355 145.918 148.296 1.00 95.60  ? 736 ILE A O   1 
ATOM   5786 C  CB  . ILE A 1 736 ? 120.430 147.969 145.691 1.00 84.72  ? 736 ILE A CB  1 
ATOM   5787 C  CG1 . ILE A 1 736 ? 121.592 148.816 145.172 1.00 87.01  ? 736 ILE A CG1 1 
ATOM   5788 C  CG2 . ILE A 1 736 ? 119.791 148.646 146.891 1.00 86.38  ? 736 ILE A CG2 1 
ATOM   5789 C  CD1 . ILE A 1 736 ? 121.161 149.971 144.306 1.00 91.60  ? 736 ILE A CD1 1 
ATOM   5790 N  N   . CYS A 1 737 ? 118.921 145.302 146.680 1.00 88.87  ? 737 CYS A N   1 
ATOM   5791 C  CA  . CYS A 1 737 ? 118.056 144.606 147.627 1.00 88.49  ? 737 CYS A CA  1 
ATOM   5792 C  C   . CYS A 1 737 ? 118.789 143.454 148.304 1.00 88.14  ? 737 CYS A C   1 
ATOM   5793 O  O   . CYS A 1 737 ? 118.713 143.288 149.528 1.00 100.17 ? 737 CYS A O   1 
ATOM   5794 C  CB  . CYS A 1 737 ? 116.800 144.096 146.922 1.00 88.17  ? 737 CYS A CB  1 
ATOM   5795 S  SG  . CYS A 1 737 ? 115.633 145.380 146.422 1.00 111.29 ? 737 CYS A SG  1 
ATOM   5796 N  N   . VAL A 1 738 ? 119.522 142.656 147.521 1.00 74.15  ? 738 VAL A N   1 
ATOM   5797 C  CA  . VAL A 1 738 ? 120.243 141.518 148.092 1.00 80.83  ? 738 VAL A CA  1 
ATOM   5798 C  C   . VAL A 1 738 ? 121.311 142.000 149.070 1.00 85.32  ? 738 VAL A C   1 
ATOM   5799 O  O   . VAL A 1 738 ? 121.474 141.445 150.168 1.00 90.10  ? 738 VAL A O   1 
ATOM   5800 C  CB  . VAL A 1 738 ? 120.847 140.651 146.972 1.00 75.97  ? 738 VAL A CB  1 
ATOM   5801 C  CG1 . VAL A 1 738 ? 121.967 139.776 147.514 1.00 75.01  ? 738 VAL A CG1 1 
ATOM   5802 C  CG2 . VAL A 1 738 ? 119.770 139.801 146.325 1.00 75.22  ? 738 VAL A CG2 1 
ATOM   5803 N  N   . ALA A 1 739 ? 122.055 143.041 148.689 1.00 83.21  ? 739 ALA A N   1 
ATOM   5804 C  CA  . ALA A 1 739 ? 123.105 143.559 149.562 1.00 80.51  ? 739 ALA A CA  1 
ATOM   5805 C  C   . ALA A 1 739 ? 122.529 144.138 150.848 1.00 87.84  ? 739 ALA A C   1 
ATOM   5806 O  O   . ALA A 1 739 ? 123.096 143.952 151.931 1.00 92.22  ? 739 ALA A O   1 
ATOM   5807 C  CB  . ALA A 1 739 ? 123.928 144.611 148.825 1.00 79.65  ? 739 ALA A CB  1 
ATOM   5808 N  N   . ILE A 1 740 ? 121.365 144.766 150.836 1.00 88.41  ? 740 ILE A N   1 
ATOM   5809 C  CA  . ILE A 1 740 ? 120.746 145.260 152.101 1.00 82.15  ? 740 ILE A CA  1 
ATOM   5810 C  C   . ILE A 1 740 ? 120.339 144.080 152.984 1.00 87.95  ? 740 ILE A C   1 
ATOM   5811 O  O   . ILE A 1 740 ? 120.564 144.145 154.158 1.00 101.54 ? 740 ILE A O   1 
ATOM   5812 C  CB  . ILE A 1 740 ? 119.546 146.189 151.832 1.00 81.97  ? 740 ILE A CB  1 
ATOM   5813 C  CG1 . ILE A 1 740 ? 119.972 147.510 151.194 1.00 89.40  ? 740 ILE A CG1 1 
ATOM   5814 C  CG2 . ILE A 1 740 ? 118.739 146.413 153.098 1.00 84.36  ? 740 ILE A CG2 1 
ATOM   5815 C  CD1 . ILE A 1 740 ? 118.816 148.318 150.677 1.00 90.18  ? 740 ILE A CD1 1 
ATOM   5816 N  N   . GLN A 1 741 ? 119.722 143.067 152.426 1.00 85.68  ? 741 GLN A N   1 
ATOM   5817 C  CA  . GLN A 1 741 ? 119.329 141.895 153.216 1.00 87.44  ? 741 GLN A CA  1 
ATOM   5818 C  C   . GLN A 1 741 ? 120.570 141.343 153.870 1.00 91.23  ? 741 GLN A C   1 
ATOM   5819 O  O   . GLN A 1 741 ? 120.505 140.995 155.028 1.00 94.71  ? 741 GLN A O   1 
ATOM   5820 C  CB  . GLN A 1 741 ? 118.773 140.765 152.371 1.00 85.97  ? 741 GLN A CB  1 
ATOM   5821 C  CG  . GLN A 1 741 ? 118.413 139.549 153.204 1.00 87.29  ? 741 GLN A CG  1 
ATOM   5822 C  CD  . GLN A 1 741 ? 117.376 139.935 154.223 1.00 92.62  ? 741 GLN A CD  1 
ATOM   5823 O  OE1 . GLN A 1 741 ? 117.627 139.980 155.421 1.00 91.06  ? 741 GLN A OE1 1 
ATOM   5824 N  NE2 . GLN A 1 741 ? 116.203 140.286 153.735 1.00 99.52  ? 741 GLN A NE2 1 
ATOM   5825 N  N   . ALA A 1 742 ? 121.649 141.254 153.118 1.00 87.55  ? 742 ALA A N   1 
ATOM   5826 C  CA  . ALA A 1 742 ? 122.823 140.657 153.749 1.00 84.59  ? 742 ALA A CA  1 
ATOM   5827 C  C   . ALA A 1 742 ? 123.365 141.545 154.862 1.00 88.54  ? 742 ALA A C   1 
ATOM   5828 O  O   . ALA A 1 742 ? 123.711 141.057 155.948 1.00 90.58  ? 742 ALA A O   1 
ATOM   5829 C  CB  . ALA A 1 742 ? 123.903 140.385 152.703 1.00 83.44  ? 742 ALA A CB  1 
ATOM   5830 N  N   . THR A 1 743 ? 123.431 142.856 154.617 1.00 90.56  ? 743 THR A N   1 
ATOM   5831 C  CA  . THR A 1 743 ? 123.893 143.783 155.646 1.00 91.44  ? 743 THR A CA  1 
ATOM   5832 C  C   . THR A 1 743 ? 122.969 143.769 156.856 1.00 93.19  ? 743 THR A C   1 
ATOM   5833 O  O   . THR A 1 743 ? 123.433 143.807 158.002 1.00 95.60  ? 743 THR A O   1 
ATOM   5834 C  CB  . THR A 1 743 ? 123.997 145.195 155.067 1.00 97.31  ? 743 THR A CB  1 
ATOM   5835 O  OG1 . THR A 1 743 ? 124.869 145.183 153.933 1.00 96.12  ? 743 THR A OG1 1 
ATOM   5836 C  CG2 . THR A 1 743 ? 124.542 146.160 156.106 1.00 97.27  ? 743 THR A CG2 1 
ATOM   5837 N  N   . LYS A 1 744 ? 121.657 143.713 156.621 1.00 91.61  ? 744 LYS A N   1 
ATOM   5838 C  CA  . LYS A 1 744 ? 120.705 143.637 157.721 1.00 90.51  ? 744 LYS A CA  1 
ATOM   5839 C  C   . LYS A 1 744 ? 120.918 142.374 158.541 1.00 94.82  ? 744 LYS A C   1 
ATOM   5840 O  O   . LYS A 1 744 ? 120.839 142.404 159.775 1.00 100.87 ? 744 LYS A O   1 
ATOM   5841 C  CB  . LYS A 1 744 ? 119.278 143.685 157.177 1.00 92.42  ? 744 LYS A CB  1 
ATOM   5842 C  CG  . LYS A 1 744 ? 118.559 144.998 157.400 1.00 98.02  ? 744 LYS A CG  1 
ATOM   5843 C  CD  . LYS A 1 744 ? 117.189 144.978 156.745 1.00 96.31  ? 744 LYS A CD  1 
ATOM   5844 C  CE  . LYS A 1 744 ? 116.270 146.030 157.342 1.00 100.42 ? 744 LYS A CE  1 
ATOM   5845 N  NZ  . LYS A 1 744 ? 116.831 147.400 157.200 1.00 101.60 ? 744 LYS A NZ  1 
ATOM   5846 N  N   . ILE A 1 745 ? 121.180 141.250 157.872 1.00 88.56  ? 745 ILE A N   1 
ATOM   5847 C  CA  . ILE A 1 745 ? 121.414 140.001 158.592 1.00 88.48  ? 745 ILE A CA  1 
ATOM   5848 C  C   . ILE A 1 745 ? 122.678 140.097 159.440 1.00 90.27  ? 745 ILE A C   1 
ATOM   5849 O  O   . ILE A 1 745 ? 122.675 139.727 160.618 1.00 91.57  ? 745 ILE A O   1 
ATOM   5850 C  CB  . ILE A 1 745 ? 121.478 138.816 157.614 1.00 85.19  ? 745 ILE A CB  1 
ATOM   5851 C  CG1 . ILE A 1 745 ? 120.103 138.565 156.994 1.00 90.90  ? 745 ILE A CG1 1 
ATOM   5852 C  CG2 . ILE A 1 745 ? 121.971 137.569 158.325 1.00 82.04  ? 745 ILE A CG2 1 
ATOM   5853 C  CD1 . ILE A 1 745 ? 119.125 137.890 157.925 1.00 91.79  ? 745 ILE A CD1 1 
ATOM   5854 N  N   . VAL A 1 746 ? 123.830 140.430 158.878 1.00 90.73  ? 746 VAL A N   1 
ATOM   5855 C  CA  . VAL A 1 746 ? 125.118 140.437 159.651 1.00 88.64  ? 746 VAL A CA  1 
ATOM   5856 C  C   . VAL A 1 746 ? 125.286 141.743 160.431 1.00 92.02  ? 746 VAL A C   1 
ATOM   5857 O  O   . VAL A 1 746 ? 126.062 141.738 161.351 1.00 77.66  ? 746 VAL A O   1 
ATOM   5858 C  CB  . VAL A 1 746 ? 126.377 140.172 158.774 1.00 84.25  ? 746 VAL A CB  1 
ATOM   5859 C  CG1 . VAL A 1 746 ? 126.259 138.915 157.929 1.00 78.98  ? 746 VAL A CG1 1 
ATOM   5860 C  CG2 . VAL A 1 746 ? 126.849 141.357 157.949 1.00 85.69  ? 746 VAL A CG2 1 
HETATM 5861 C  CHA . HEM B 2 .   ? 131.249 143.469 130.284 1.00 66.94  ? 801 HEM A CHA 1 
HETATM 5862 C  CHB . HEM B 2 .   ? 127.537 146.225 131.581 1.00 66.63  ? 801 HEM A CHB 1 
HETATM 5863 C  CHC . HEM B 2 .   ? 126.566 143.201 135.288 1.00 64.76  ? 801 HEM A CHC 1 
HETATM 5864 C  CHD . HEM B 2 .   ? 130.422 140.595 134.099 1.00 61.64  ? 801 HEM A CHD 1 
HETATM 5865 C  C1A . HEM B 2 .   ? 130.358 144.506 130.360 1.00 64.90  ? 801 HEM A C1A 1 
HETATM 5866 C  C2A . HEM B 2 .   ? 130.397 145.652 129.553 1.00 62.26  ? 801 HEM A C2A 1 
HETATM 5867 C  C3A . HEM B 2 .   ? 129.351 146.432 129.939 1.00 64.42  ? 801 HEM A C3A 1 
HETATM 5868 C  C4A . HEM B 2 .   ? 128.659 145.758 130.949 1.00 65.62  ? 801 HEM A C4A 1 
HETATM 5869 C  CMA . HEM B 2 .   ? 128.958 147.776 129.372 1.00 72.70  ? 801 HEM A CMA 1 
HETATM 5870 C  CAA . HEM B 2 .   ? 131.440 146.013 128.491 1.00 66.12  ? 801 HEM A CAA 1 
HETATM 5871 C  CBA . HEM B 2 .   ? 131.123 145.595 127.049 1.00 73.80  ? 801 HEM A CBA 1 
HETATM 5872 C  CGA . HEM B 2 .   ? 132.022 146.294 126.040 1.00 78.06  ? 801 HEM A CGA 1 
HETATM 5873 O  O1A . HEM B 2 .   ? 131.672 147.291 125.393 1.00 77.97  ? 801 HEM A O1A 1 
HETATM 5874 O  O2A . HEM B 2 .   ? 133.157 145.900 125.796 1.00 78.05  ? 801 HEM A O2A 1 
HETATM 5875 C  C1B . HEM B 2 .   ? 126.955 145.606 132.683 1.00 69.43  ? 801 HEM A C1B 1 
HETATM 5876 C  C2B . HEM B 2 .   ? 125.790 146.108 133.272 1.00 67.47  ? 801 HEM A C2B 1 
HETATM 5877 C  C3B . HEM B 2 .   ? 125.489 145.288 134.322 1.00 67.79  ? 801 HEM A C3B 1 
HETATM 5878 C  C4B . HEM B 2 .   ? 126.519 144.239 134.340 1.00 69.11  ? 801 HEM A C4B 1 
HETATM 5879 C  CMB . HEM B 2 .   ? 125.075 147.341 132.806 1.00 68.10  ? 801 HEM A CMB 1 
HETATM 5880 C  CAB . HEM B 2 .   ? 124.366 145.357 135.278 1.00 69.36  ? 801 HEM A CAB 1 
HETATM 5881 C  CBB . HEM B 2 .   ? 123.930 146.500 135.747 1.00 76.16  ? 801 HEM A CBB 1 
HETATM 5882 C  C1C . HEM B 2 .   ? 127.552 142.225 135.326 1.00 66.50  ? 801 HEM A C1C 1 
HETATM 5883 C  C2C . HEM B 2 .   ? 127.683 141.203 136.269 1.00 69.87  ? 801 HEM A C2C 1 
HETATM 5884 C  C3C . HEM B 2 .   ? 128.786 140.464 135.919 1.00 66.91  ? 801 HEM A C3C 1 
HETATM 5885 C  C4C . HEM B 2 .   ? 129.324 141.056 134.757 1.00 63.10  ? 801 HEM A C4C 1 
HETATM 5886 C  CMC . HEM B 2 .   ? 126.794 140.945 137.457 1.00 65.93  ? 801 HEM A CMC 1 
HETATM 5887 C  CAC . HEM B 2 .   ? 129.320 139.271 136.611 1.00 64.88  ? 801 HEM A CAC 1 
HETATM 5888 C  CBC . HEM B 2 .   ? 129.566 139.259 137.909 1.00 69.68  ? 801 HEM A CBC 1 
HETATM 5889 C  C1D . HEM B 2 .   ? 130.919 141.187 132.942 1.00 69.40  ? 801 HEM A C1D 1 
HETATM 5890 C  C2D . HEM B 2 .   ? 132.044 140.616 132.219 1.00 70.00  ? 801 HEM A C2D 1 
HETATM 5891 C  C3D . HEM B 2 .   ? 132.261 141.414 131.177 1.00 65.96  ? 801 HEM A C3D 1 
HETATM 5892 C  C4D . HEM B 2 .   ? 131.270 142.465 131.238 1.00 69.42  ? 801 HEM A C4D 1 
HETATM 5893 C  CMD . HEM B 2 .   ? 132.829 139.377 132.577 1.00 68.62  ? 801 HEM A CMD 1 
HETATM 5894 C  CAD . HEM B 2 .   ? 133.329 141.236 130.131 1.00 66.96  ? 801 HEM A CAD 1 
HETATM 5895 C  CBD . HEM B 2 .   ? 132.688 140.259 129.167 1.00 62.14  ? 801 HEM A CBD 1 
HETATM 5896 C  CGD . HEM B 2 .   ? 133.338 140.112 127.834 1.00 73.76  ? 801 HEM A CGD 1 
HETATM 5897 O  O1D . HEM B 2 .   ? 134.349 140.729 127.555 1.00 68.72  ? 801 HEM A O1D 1 
HETATM 5898 O  O2D . HEM B 2 .   ? 132.880 139.355 126.981 1.00 85.45  ? 801 HEM A O2D 1 
HETATM 5899 N  NA  . HEM B 2 .   ? 129.288 144.589 131.218 1.00 69.79  ? 801 HEM A NA  1 
HETATM 5900 N  NB  . HEM B 2 .   ? 127.344 144.517 133.328 1.00 75.07  ? 801 HEM A NB  1 
HETATM 5901 N  NC  . HEM B 2 .   ? 128.552 142.122 134.421 1.00 62.27  ? 801 HEM A NC  1 
HETATM 5902 N  ND  . HEM B 2 .   ? 130.493 142.294 132.321 1.00 74.46  ? 801 HEM A ND  1 
HETATM 5903 FE FE  . HEM B 2 .   ? 129.037 143.391 132.805 1.00 96.68  ? 801 HEM A FE  1 
HETATM 5904 C  CHA . HEM C 2 .   ? 134.120 132.871 126.550 1.00 82.57  ? 802 HEM A CHA 1 
HETATM 5905 C  CHB . HEM C 2 .   ? 132.744 132.230 131.125 1.00 82.64  ? 802 HEM A CHB 1 
HETATM 5906 C  CHC . HEM C 2 .   ? 131.166 127.808 130.003 1.00 80.73  ? 802 HEM A CHC 1 
HETATM 5907 C  CHD . HEM C 2 .   ? 132.757 128.371 125.480 1.00 83.66  ? 802 HEM A CHD 1 
HETATM 5908 C  C1A . HEM C 2 .   ? 133.789 133.102 127.858 1.00 78.35  ? 802 HEM A C1A 1 
HETATM 5909 C  C2A . HEM C 2 .   ? 133.847 134.337 128.523 1.00 75.00  ? 802 HEM A C2A 1 
HETATM 5910 C  C3A . HEM C 2 .   ? 133.481 134.140 129.787 1.00 73.66  ? 802 HEM A C3A 1 
HETATM 5911 C  C4A . HEM C 2 .   ? 133.173 132.792 129.951 1.00 75.36  ? 802 HEM A C4A 1 
HETATM 5912 C  CMA . HEM C 2 .   ? 133.417 135.213 130.825 1.00 79.49  ? 802 HEM A CMA 1 
HETATM 5913 C  CAA . HEM C 2 .   ? 134.253 135.687 128.013 1.00 74.88  ? 802 HEM A CAA 1 
HETATM 5914 C  CBA . HEM C 2 .   ? 135.452 135.539 127.085 1.00 79.93  ? 802 HEM A CBA 1 
HETATM 5915 C  CGA . HEM C 2 .   ? 136.262 136.791 127.049 1.00 87.24  ? 802 HEM A CGA 1 
HETATM 5916 O  O1A . HEM C 2 .   ? 135.985 137.803 127.690 1.00 93.91  ? 802 HEM A O1A 1 
HETATM 5917 O  O2A . HEM C 2 .   ? 137.290 136.841 126.383 1.00 85.61  ? 802 HEM A O2A 1 
HETATM 5918 C  C1B . HEM C 2 .   ? 132.211 130.952 131.172 1.00 83.06  ? 802 HEM A C1B 1 
HETATM 5919 C  C2B . HEM C 2 .   ? 131.694 130.443 132.368 1.00 75.75  ? 802 HEM A C2B 1 
HETATM 5920 C  C3B . HEM C 2 .   ? 131.239 129.203 132.089 1.00 79.11  ? 802 HEM A C3B 1 
HETATM 5921 C  C4B . HEM C 2 .   ? 131.505 128.980 130.660 1.00 85.69  ? 802 HEM A C4B 1 
HETATM 5922 C  CMB . HEM C 2 .   ? 131.665 131.169 133.682 1.00 72.65  ? 802 HEM A CMB 1 
HETATM 5923 C  CAB . HEM C 2 .   ? 130.612 128.244 133.005 1.00 74.57  ? 802 HEM A CAB 1 
HETATM 5924 C  CBB . HEM C 2 .   ? 129.681 128.626 133.858 1.00 83.96  ? 802 HEM A CBB 1 
HETATM 5925 C  C1C . HEM C 2 .   ? 131.432 127.587 128.668 1.00 80.61  ? 802 HEM A C1C 1 
HETATM 5926 C  C2C . HEM C 2 .   ? 131.082 126.448 127.956 1.00 82.89  ? 802 HEM A C2C 1 
HETATM 5927 C  C3C . HEM C 2 .   ? 131.539 126.607 126.661 1.00 85.48  ? 802 HEM A C3C 1 
HETATM 5928 C  C4C . HEM C 2 .   ? 132.167 127.860 126.599 1.00 85.23  ? 802 HEM A C4C 1 
HETATM 5929 C  CMC . HEM C 2 .   ? 130.342 125.271 128.530 1.00 79.86  ? 802 HEM A CMC 1 
HETATM 5930 C  CAC . HEM C 2 .   ? 131.417 125.660 125.537 1.00 85.54  ? 802 HEM A CAC 1 
HETATM 5931 C  CBC . HEM C 2 .   ? 130.301 124.991 125.320 1.00 86.14  ? 802 HEM A CBC 1 
HETATM 5932 C  C1D . HEM C 2 .   ? 133.266 129.656 125.458 1.00 81.19  ? 802 HEM A C1D 1 
HETATM 5933 C  C2D . HEM C 2 .   ? 133.844 130.204 124.240 1.00 73.61  ? 802 HEM A C2D 1 
HETATM 5934 C  C3D . HEM C 2 .   ? 134.211 131.448 124.531 1.00 73.26  ? 802 HEM A C3D 1 
HETATM 5935 C  C4D . HEM C 2 .   ? 133.876 131.661 125.931 1.00 79.52  ? 802 HEM A C4D 1 
HETATM 5936 C  CMD . HEM C 2 .   ? 133.988 129.517 122.908 1.00 77.42  ? 802 HEM A CMD 1 
HETATM 5937 C  CAD . HEM C 2 .   ? 134.887 132.401 123.601 1.00 78.12  ? 802 HEM A CAD 1 
HETATM 5938 C  CBD . HEM C 2 .   ? 134.057 133.547 123.054 1.00 78.69  ? 802 HEM A CBD 1 
HETATM 5939 C  CGD . HEM C 2 .   ? 135.029 134.572 122.550 1.00 91.58  ? 802 HEM A CGD 1 
HETATM 5940 O  O1D . HEM C 2 .   ? 136.228 134.473 122.813 1.00 95.01  ? 802 HEM A O1D 1 
HETATM 5941 O  O2D . HEM C 2 .   ? 134.662 135.542 121.885 1.00 95.90  ? 802 HEM A O2D 1 
HETATM 5942 N  NA  . HEM C 2 .   ? 133.358 132.162 128.756 1.00 73.03  ? 802 HEM A NA  1 
HETATM 5943 N  NB  . HEM C 2 .   ? 132.091 130.074 130.179 1.00 86.97  ? 802 HEM A NB  1 
HETATM 5944 N  NC  . HEM C 2 .   ? 132.088 128.432 127.835 1.00 84.74  ? 802 HEM A NC  1 
HETATM 5945 N  ND  . HEM C 2 .   ? 133.321 130.564 126.439 1.00 85.10  ? 802 HEM A ND  1 
HETATM 5946 FE FE  . HEM C 2 .   ? 132.718 130.373 128.198 1.00 101.80 ? 802 HEM A FE  1 
HETATM 5947 FE FE  . FE  D 3 .   ? 135.932 128.670 128.317 1.00 125.28 ? 803 FE  A FE  1 
HETATM 5948 CA CA  . CA  E 4 .   ? 136.374 140.281 126.173 1.00 145.54 ? 804 CA  A CA  1 
HETATM 5949 O  O   . HOH F 5 .   ? 126.164 146.165 122.584 1.00 30.00  ? 901 HOH A O   1 
HETATM 5950 O  O   . HOH F 5 .   ? 145.719 130.036 115.506 1.00 30.00  ? 902 HOH A O   1 
HETATM 5951 O  O   . HOH F 5 .   ? 130.230 147.721 123.401 1.00 30.00  ? 903 HOH A O   1 
HETATM 5952 O  O   . HOH F 5 .   ? 136.121 136.827 111.775 1.00 30.00  ? 904 HOH A O   1 
HETATM 5953 O  O   . HOH F 5 .   ? 137.543 134.148 124.929 1.00 30.00  ? 905 HOH A O   1 
HETATM 5954 O  O   . HOH F 5 .   ? 135.392 137.108 114.658 1.00 30.00  ? 906 HOH A O   1 
HETATM 5955 O  O   . HOH F 5 .   ? 138.390 154.736 127.147 1.00 30.00  ? 907 HOH A O   1 
HETATM 5956 O  O   . HOH F 5 .   ? 139.861 138.216 126.407 1.00 30.00  ? 908 HOH A O   1 
HETATM 5957 O  O   . HOH F 5 .   ? 133.312 150.435 116.544 1.00 30.00  ? 909 HOH A O   1 
HETATM 5958 O  O   . HOH F 5 .   ? 128.592 144.403 124.730 1.00 30.00  ? 910 HOH A O   1 
HETATM 5959 O  O   . HOH F 5 .   ? 138.339 132.954 122.114 1.00 30.00  ? 911 HOH A O   1 
HETATM 5960 O  O   . HOH F 5 .   ? 137.312 152.089 124.142 1.00 30.00  ? 912 HOH A O   1 
HETATM 5961 O  O   . HOH F 5 .   ? 136.955 147.838 112.313 1.00 30.00  ? 913 HOH A O   1 
HETATM 5962 O  O   . HOH F 5 .   ? 141.691 132.805 119.750 1.00 30.00  ? 914 HOH A O   1 
HETATM 5963 O  O   . HOH F 5 .   ? 136.292 149.161 123.451 1.00 30.00  ? 915 HOH A O   1 
HETATM 5964 O  O   . HOH F 5 .   ? 138.103 141.063 108.994 1.00 30.00  ? 916 HOH A O   1 
HETATM 5965 O  O   . HOH F 5 .   ? 133.508 147.459 117.791 1.00 30.00  ? 917 HOH A O   1 
HETATM 5966 O  O   . HOH F 5 .   ? 139.085 130.715 119.840 1.00 30.00  ? 918 HOH A O   1 
HETATM 5967 O  O   . HOH F 5 .   ? 131.871 143.709 119.268 1.00 30.00  ? 919 HOH A O   1 
HETATM 5968 O  O   . HOH F 5 .   ? 147.474 127.840 112.461 1.00 30.00  ? 920 HOH A O   1 
HETATM 5969 O  O   . HOH F 5 .   ? 137.524 138.547 124.146 1.00 30.00  ? 921 HOH A O   1 
HETATM 5970 O  O   . HOH F 5 .   ? 135.913 156.946 127.919 1.00 30.00  ? 922 HOH A O   1 
HETATM 5971 O  O   . HOH F 5 .   ? 137.836 145.614 113.368 1.00 30.00  ? 923 HOH A O   1 
HETATM 5972 O  O   . HOH F 5 .   ? 140.150 128.096 110.203 1.00 30.00  ? 924 HOH A O   1 
HETATM 5973 O  O   . HOH F 5 .   ? 142.794 156.846 135.133 1.00 30.00  ? 925 HOH A O   1 
HETATM 5974 O  O   . HOH F 5 .   ? 142.829 154.427 128.209 1.00 30.00  ? 926 HOH A O   1 
HETATM 5975 O  O   . HOH F 5 .   ? 128.112 144.010 127.982 1.00 30.00  ? 927 HOH A O   1 
HETATM 5976 O  O   . HOH F 5 .   ? 144.268 149.843 123.625 1.00 30.00  ? 928 HOH A O   1 
HETATM 5977 O  O   . HOH F 5 .   ? 140.908 155.614 126.554 1.00 30.00  ? 929 HOH A O   1 
HETATM 5978 O  O   . HOH F 5 .   ? 131.425 153.110 117.137 1.00 30.00  ? 930 HOH A O   1 
HETATM 5979 O  O   . HOH F 5 .   ? 126.993 147.548 120.884 1.00 30.00  ? 931 HOH A O   1 
HETATM 5980 O  O   . HOH F 5 .   ? 127.695 147.361 124.626 1.00 30.00  ? 932 HOH A O   1 
# 
