data_8ZCX
# 
_entry.id   8ZCX 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8ZCX         pdb_00008zcx 10.2210/pdb8zcx/pdb 
WWPDB D_1300047495 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-05-07 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8ZCX 
_pdbx_database_status.recvd_initial_deposition_date   2024-04-30 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBC 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 3 
_pdbx_contact_author.email              zhangwy@tib.cas.cn 
_pdbx_contact_author.name_first         Wuyuan 
_pdbx_contact_author.name_last          Zhang 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0001-7954-7700 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Zhang, J.' 1 ? 
'Han, Y.'   2 ? 
'Liu, W.'   3 ? 
'Zhang, W.' 4 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'Crystal Structure of a novel Aldehyde Dehydrogenase from Klebsiella pneumoniae' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Zhang, J.' 1 ? 
primary 'Han, Y.'   2 ? 
primary 'Liu, W.'   3 ? 
primary 'Zhang, W.' 4 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer man 'Aldehyde dehydrogenase' 52733.508 4   1.2.1.3,1.2.1.28 ? ? 
;Sequence reference for Klebsiella pneumoniae (573) is not available in UniProt at the time of biocuration. Current sequence reference is from UniProt ID A0A069Q1D5.
;
2 water   nat water                    18.015    192 ?                ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        'Aldehyde dehydrogenase family protein,Putative aldehyde dehydrogenase' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MSDSRYTDLGLQPLAGEWRHGRAGRRLKVSNPFDGSLLLEIEQADRDDLDAAYAKAAEVQPAWAALGPSARAAVLYKAVE
VFDRRHEEIVDWIIRESGSTRLKAEIEWGAARAITLESASFPARVHGRIVESDVPGKESRVYRSAIGVVGVISPWNFPLH
LTQRSIAPALALGNAVVVKPASDTPVCGGLLLARIFEEAGLPAGLFSVVVGPGSEIGDAFVEHPVPGLVTFTGSTPVGRN
IGRIASGGAHLKHVALELGGNSPFVVLGDADLEQAVSAAVFGKFLHQGQICMAINRIIVEDSLYDAFAARFVERVKGLRV
GDPQRADTAVGPIVNARQLEGLLEKIRLARQEGAKPLYEGGVDGQLLAPHVFGEVTATMEIARDEIFGPLVGLLRARDEA
HALELANASEYGLSSAVFSRDLERAVRFARQLRAGMTHVNDIPVNDEANAPFGGEKNSGLGRFNGDWAIEEFTTDHWISV
QHAPRQYPF
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MSDSRYTDLGLQPLAGEWRHGRAGRRLKVSNPFDGSLLLEIEQADRDDLDAAYAKAAEVQPAWAALGPSARAAVLYKAVE
VFDRRHEEIVDWIIRESGSTRLKAEIEWGAARAITLESASFPARVHGRIVESDVPGKESRVYRSAIGVVGVISPWNFPLH
LTQRSIAPALALGNAVVVKPASDTPVCGGLLLARIFEEAGLPAGLFSVVVGPGSEIGDAFVEHPVPGLVTFTGSTPVGRN
IGRIASGGAHLKHVALELGGNSPFVVLGDADLEQAVSAAVFGKFLHQGQICMAINRIIVEDSLYDAFAARFVERVKGLRV
GDPQRADTAVGPIVNARQLEGLLEKIRLARQEGAKPLYEGGVDGQLLAPHVFGEVTATMEIARDEIFGPLVGLLRARDEA
HALELANASEYGLSSAVFSRDLERAVRFARQLRAGMTHVNDIPVNDEANAPFGGEKNSGLGRFNGDWAIEEFTTDHWISV
QHAPRQYPF
;
_entity_poly.pdbx_strand_id                 A,B,C,D 
_entity_poly.pdbx_target_identifier         ? 
# 
_pdbx_entity_nonpoly.entity_id   2 
_pdbx_entity_nonpoly.name        water 
_pdbx_entity_nonpoly.comp_id     HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   SER n 
1 3   ASP n 
1 4   SER n 
1 5   ARG n 
1 6   TYR n 
1 7   THR n 
1 8   ASP n 
1 9   LEU n 
1 10  GLY n 
1 11  LEU n 
1 12  GLN n 
1 13  PRO n 
1 14  LEU n 
1 15  ALA n 
1 16  GLY n 
1 17  GLU n 
1 18  TRP n 
1 19  ARG n 
1 20  HIS n 
1 21  GLY n 
1 22  ARG n 
1 23  ALA n 
1 24  GLY n 
1 25  ARG n 
1 26  ARG n 
1 27  LEU n 
1 28  LYS n 
1 29  VAL n 
1 30  SER n 
1 31  ASN n 
1 32  PRO n 
1 33  PHE n 
1 34  ASP n 
1 35  GLY n 
1 36  SER n 
1 37  LEU n 
1 38  LEU n 
1 39  LEU n 
1 40  GLU n 
1 41  ILE n 
1 42  GLU n 
1 43  GLN n 
1 44  ALA n 
1 45  ASP n 
1 46  ARG n 
1 47  ASP n 
1 48  ASP n 
1 49  LEU n 
1 50  ASP n 
1 51  ALA n 
1 52  ALA n 
1 53  TYR n 
1 54  ALA n 
1 55  LYS n 
1 56  ALA n 
1 57  ALA n 
1 58  GLU n 
1 59  VAL n 
1 60  GLN n 
1 61  PRO n 
1 62  ALA n 
1 63  TRP n 
1 64  ALA n 
1 65  ALA n 
1 66  LEU n 
1 67  GLY n 
1 68  PRO n 
1 69  SER n 
1 70  ALA n 
1 71  ARG n 
1 72  ALA n 
1 73  ALA n 
1 74  VAL n 
1 75  LEU n 
1 76  TYR n 
1 77  LYS n 
1 78  ALA n 
1 79  VAL n 
1 80  GLU n 
1 81  VAL n 
1 82  PHE n 
1 83  ASP n 
1 84  ARG n 
1 85  ARG n 
1 86  HIS n 
1 87  GLU n 
1 88  GLU n 
1 89  ILE n 
1 90  VAL n 
1 91  ASP n 
1 92  TRP n 
1 93  ILE n 
1 94  ILE n 
1 95  ARG n 
1 96  GLU n 
1 97  SER n 
1 98  GLY n 
1 99  SER n 
1 100 THR n 
1 101 ARG n 
1 102 LEU n 
1 103 LYS n 
1 104 ALA n 
1 105 GLU n 
1 106 ILE n 
1 107 GLU n 
1 108 TRP n 
1 109 GLY n 
1 110 ALA n 
1 111 ALA n 
1 112 ARG n 
1 113 ALA n 
1 114 ILE n 
1 115 THR n 
1 116 LEU n 
1 117 GLU n 
1 118 SER n 
1 119 ALA n 
1 120 SER n 
1 121 PHE n 
1 122 PRO n 
1 123 ALA n 
1 124 ARG n 
1 125 VAL n 
1 126 HIS n 
1 127 GLY n 
1 128 ARG n 
1 129 ILE n 
1 130 VAL n 
1 131 GLU n 
1 132 SER n 
1 133 ASP n 
1 134 VAL n 
1 135 PRO n 
1 136 GLY n 
1 137 LYS n 
1 138 GLU n 
1 139 SER n 
1 140 ARG n 
1 141 VAL n 
1 142 TYR n 
1 143 ARG n 
1 144 SER n 
1 145 ALA n 
1 146 ILE n 
1 147 GLY n 
1 148 VAL n 
1 149 VAL n 
1 150 GLY n 
1 151 VAL n 
1 152 ILE n 
1 153 SER n 
1 154 PRO n 
1 155 TRP n 
1 156 ASN n 
1 157 PHE n 
1 158 PRO n 
1 159 LEU n 
1 160 HIS n 
1 161 LEU n 
1 162 THR n 
1 163 GLN n 
1 164 ARG n 
1 165 SER n 
1 166 ILE n 
1 167 ALA n 
1 168 PRO n 
1 169 ALA n 
1 170 LEU n 
1 171 ALA n 
1 172 LEU n 
1 173 GLY n 
1 174 ASN n 
1 175 ALA n 
1 176 VAL n 
1 177 VAL n 
1 178 VAL n 
1 179 LYS n 
1 180 PRO n 
1 181 ALA n 
1 182 SER n 
1 183 ASP n 
1 184 THR n 
1 185 PRO n 
1 186 VAL n 
1 187 CYS n 
1 188 GLY n 
1 189 GLY n 
1 190 LEU n 
1 191 LEU n 
1 192 LEU n 
1 193 ALA n 
1 194 ARG n 
1 195 ILE n 
1 196 PHE n 
1 197 GLU n 
1 198 GLU n 
1 199 ALA n 
1 200 GLY n 
1 201 LEU n 
1 202 PRO n 
1 203 ALA n 
1 204 GLY n 
1 205 LEU n 
1 206 PHE n 
1 207 SER n 
1 208 VAL n 
1 209 VAL n 
1 210 VAL n 
1 211 GLY n 
1 212 PRO n 
1 213 GLY n 
1 214 SER n 
1 215 GLU n 
1 216 ILE n 
1 217 GLY n 
1 218 ASP n 
1 219 ALA n 
1 220 PHE n 
1 221 VAL n 
1 222 GLU n 
1 223 HIS n 
1 224 PRO n 
1 225 VAL n 
1 226 PRO n 
1 227 GLY n 
1 228 LEU n 
1 229 VAL n 
1 230 THR n 
1 231 PHE n 
1 232 THR n 
1 233 GLY n 
1 234 SER n 
1 235 THR n 
1 236 PRO n 
1 237 VAL n 
1 238 GLY n 
1 239 ARG n 
1 240 ASN n 
1 241 ILE n 
1 242 GLY n 
1 243 ARG n 
1 244 ILE n 
1 245 ALA n 
1 246 SER n 
1 247 GLY n 
1 248 GLY n 
1 249 ALA n 
1 250 HIS n 
1 251 LEU n 
1 252 LYS n 
1 253 HIS n 
1 254 VAL n 
1 255 ALA n 
1 256 LEU n 
1 257 GLU n 
1 258 LEU n 
1 259 GLY n 
1 260 GLY n 
1 261 ASN n 
1 262 SER n 
1 263 PRO n 
1 264 PHE n 
1 265 VAL n 
1 266 VAL n 
1 267 LEU n 
1 268 GLY n 
1 269 ASP n 
1 270 ALA n 
1 271 ASP n 
1 272 LEU n 
1 273 GLU n 
1 274 GLN n 
1 275 ALA n 
1 276 VAL n 
1 277 SER n 
1 278 ALA n 
1 279 ALA n 
1 280 VAL n 
1 281 PHE n 
1 282 GLY n 
1 283 LYS n 
1 284 PHE n 
1 285 LEU n 
1 286 HIS n 
1 287 GLN n 
1 288 GLY n 
1 289 GLN n 
1 290 ILE n 
1 291 CYS n 
1 292 MET n 
1 293 ALA n 
1 294 ILE n 
1 295 ASN n 
1 296 ARG n 
1 297 ILE n 
1 298 ILE n 
1 299 VAL n 
1 300 GLU n 
1 301 ASP n 
1 302 SER n 
1 303 LEU n 
1 304 TYR n 
1 305 ASP n 
1 306 ALA n 
1 307 PHE n 
1 308 ALA n 
1 309 ALA n 
1 310 ARG n 
1 311 PHE n 
1 312 VAL n 
1 313 GLU n 
1 314 ARG n 
1 315 VAL n 
1 316 LYS n 
1 317 GLY n 
1 318 LEU n 
1 319 ARG n 
1 320 VAL n 
1 321 GLY n 
1 322 ASP n 
1 323 PRO n 
1 324 GLN n 
1 325 ARG n 
1 326 ALA n 
1 327 ASP n 
1 328 THR n 
1 329 ALA n 
1 330 VAL n 
1 331 GLY n 
1 332 PRO n 
1 333 ILE n 
1 334 VAL n 
1 335 ASN n 
1 336 ALA n 
1 337 ARG n 
1 338 GLN n 
1 339 LEU n 
1 340 GLU n 
1 341 GLY n 
1 342 LEU n 
1 343 LEU n 
1 344 GLU n 
1 345 LYS n 
1 346 ILE n 
1 347 ARG n 
1 348 LEU n 
1 349 ALA n 
1 350 ARG n 
1 351 GLN n 
1 352 GLU n 
1 353 GLY n 
1 354 ALA n 
1 355 LYS n 
1 356 PRO n 
1 357 LEU n 
1 358 TYR n 
1 359 GLU n 
1 360 GLY n 
1 361 GLY n 
1 362 VAL n 
1 363 ASP n 
1 364 GLY n 
1 365 GLN n 
1 366 LEU n 
1 367 LEU n 
1 368 ALA n 
1 369 PRO n 
1 370 HIS n 
1 371 VAL n 
1 372 PHE n 
1 373 GLY n 
1 374 GLU n 
1 375 VAL n 
1 376 THR n 
1 377 ALA n 
1 378 THR n 
1 379 MET n 
1 380 GLU n 
1 381 ILE n 
1 382 ALA n 
1 383 ARG n 
1 384 ASP n 
1 385 GLU n 
1 386 ILE n 
1 387 PHE n 
1 388 GLY n 
1 389 PRO n 
1 390 LEU n 
1 391 VAL n 
1 392 GLY n 
1 393 LEU n 
1 394 LEU n 
1 395 ARG n 
1 396 ALA n 
1 397 ARG n 
1 398 ASP n 
1 399 GLU n 
1 400 ALA n 
1 401 HIS n 
1 402 ALA n 
1 403 LEU n 
1 404 GLU n 
1 405 LEU n 
1 406 ALA n 
1 407 ASN n 
1 408 ALA n 
1 409 SER n 
1 410 GLU n 
1 411 TYR n 
1 412 GLY n 
1 413 LEU n 
1 414 SER n 
1 415 SER n 
1 416 ALA n 
1 417 VAL n 
1 418 PHE n 
1 419 SER n 
1 420 ARG n 
1 421 ASP n 
1 422 LEU n 
1 423 GLU n 
1 424 ARG n 
1 425 ALA n 
1 426 VAL n 
1 427 ARG n 
1 428 PHE n 
1 429 ALA n 
1 430 ARG n 
1 431 GLN n 
1 432 LEU n 
1 433 ARG n 
1 434 ALA n 
1 435 GLY n 
1 436 MET n 
1 437 THR n 
1 438 HIS n 
1 439 VAL n 
1 440 ASN n 
1 441 ASP n 
1 442 ILE n 
1 443 PRO n 
1 444 VAL n 
1 445 ASN n 
1 446 ASP n 
1 447 GLU n 
1 448 ALA n 
1 449 ASN n 
1 450 ALA n 
1 451 PRO n 
1 452 PHE n 
1 453 GLY n 
1 454 GLY n 
1 455 GLU n 
1 456 LYS n 
1 457 ASN n 
1 458 SER n 
1 459 GLY n 
1 460 LEU n 
1 461 GLY n 
1 462 ARG n 
1 463 PHE n 
1 464 ASN n 
1 465 GLY n 
1 466 ASP n 
1 467 TRP n 
1 468 ALA n 
1 469 ILE n 
1 470 GLU n 
1 471 GLU n 
1 472 PHE n 
1 473 THR n 
1 474 THR n 
1 475 ASP n 
1 476 HIS n 
1 477 TRP n 
1 478 ILE n 
1 479 SER n 
1 480 VAL n 
1 481 GLN n 
1 482 HIS n 
1 483 ALA n 
1 484 PRO n 
1 485 ARG n 
1 486 GLN n 
1 487 TYR n 
1 488 PRO n 
1 489 PHE n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   489 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 
'yfmT, xylC_1, CAZ10_02010, DT376_04100, IPC1295_07430, NCTC13621_03651, PAERUG_P19_London_7_VIM_2_05_10_05035' 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Klebsiella pneumoniae' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     573 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      
;Escherichia coli 'BL21-Gold(DE3)pLysS AG'
;
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     866768 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER           ? 'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   SER 2   2   ?   ?   ?   A . n 
A 1 3   ASP 3   3   ?   ?   ?   A . n 
A 1 4   SER 4   4   4   SER SER A . n 
A 1 5   ARG 5   5   5   ARG ARG A . n 
A 1 6   TYR 6   6   6   TYR TYR A . n 
A 1 7   THR 7   7   7   THR THR A . n 
A 1 8   ASP 8   8   8   ASP ASP A . n 
A 1 9   LEU 9   9   9   LEU LEU A . n 
A 1 10  GLY 10  10  10  GLY GLY A . n 
A 1 11  LEU 11  11  11  LEU LEU A . n 
A 1 12  GLN 12  12  12  GLN GLN A . n 
A 1 13  PRO 13  13  13  PRO PRO A . n 
A 1 14  LEU 14  14  14  LEU LEU A . n 
A 1 15  ALA 15  15  15  ALA ALA A . n 
A 1 16  GLY 16  16  16  GLY GLY A . n 
A 1 17  GLU 17  17  17  GLU GLU A . n 
A 1 18  TRP 18  18  18  TRP TRP A . n 
A 1 19  ARG 19  19  19  ARG ARG A . n 
A 1 20  HIS 20  20  20  HIS HIS A . n 
A 1 21  GLY 21  21  21  GLY GLY A . n 
A 1 22  ARG 22  22  22  ARG ARG A . n 
A 1 23  ALA 23  23  23  ALA ALA A . n 
A 1 24  GLY 24  24  24  GLY GLY A . n 
A 1 25  ARG 25  25  25  ARG ARG A . n 
A 1 26  ARG 26  26  26  ARG ARG A . n 
A 1 27  LEU 27  27  27  LEU LEU A . n 
A 1 28  LYS 28  28  28  LYS LYS A . n 
A 1 29  VAL 29  29  29  VAL VAL A . n 
A 1 30  SER 30  30  30  SER SER A . n 
A 1 31  ASN 31  31  31  ASN ASN A . n 
A 1 32  PRO 32  32  32  PRO PRO A . n 
A 1 33  PHE 33  33  33  PHE PHE A . n 
A 1 34  ASP 34  34  34  ASP ASP A . n 
A 1 35  GLY 35  35  35  GLY GLY A . n 
A 1 36  SER 36  36  36  SER SER A . n 
A 1 37  LEU 37  37  37  LEU LEU A . n 
A 1 38  LEU 38  38  38  LEU LEU A . n 
A 1 39  LEU 39  39  39  LEU LEU A . n 
A 1 40  GLU 40  40  40  GLU GLU A . n 
A 1 41  ILE 41  41  41  ILE ILE A . n 
A 1 42  GLU 42  42  42  GLU GLU A . n 
A 1 43  GLN 43  43  43  GLN GLN A . n 
A 1 44  ALA 44  44  44  ALA ALA A . n 
A 1 45  ASP 45  45  45  ASP ASP A . n 
A 1 46  ARG 46  46  46  ARG ARG A . n 
A 1 47  ASP 47  47  47  ASP ASP A . n 
A 1 48  ASP 48  48  48  ASP ASP A . n 
A 1 49  LEU 49  49  49  LEU LEU A . n 
A 1 50  ASP 50  50  50  ASP ASP A . n 
A 1 51  ALA 51  51  51  ALA ALA A . n 
A 1 52  ALA 52  52  52  ALA ALA A . n 
A 1 53  TYR 53  53  53  TYR TYR A . n 
A 1 54  ALA 54  54  54  ALA ALA A . n 
A 1 55  LYS 55  55  55  LYS LYS A . n 
A 1 56  ALA 56  56  56  ALA ALA A . n 
A 1 57  ALA 57  57  57  ALA ALA A . n 
A 1 58  GLU 58  58  58  GLU GLU A . n 
A 1 59  VAL 59  59  59  VAL VAL A . n 
A 1 60  GLN 60  60  60  GLN GLN A . n 
A 1 61  PRO 61  61  61  PRO PRO A . n 
A 1 62  ALA 62  62  62  ALA ALA A . n 
A 1 63  TRP 63  63  63  TRP TRP A . n 
A 1 64  ALA 64  64  64  ALA ALA A . n 
A 1 65  ALA 65  65  65  ALA ALA A . n 
A 1 66  LEU 66  66  66  LEU LEU A . n 
A 1 67  GLY 67  67  67  GLY GLY A . n 
A 1 68  PRO 68  68  68  PRO PRO A . n 
A 1 69  SER 69  69  69  SER SER A . n 
A 1 70  ALA 70  70  70  ALA ALA A . n 
A 1 71  ARG 71  71  71  ARG ARG A . n 
A 1 72  ALA 72  72  72  ALA ALA A . n 
A 1 73  ALA 73  73  73  ALA ALA A . n 
A 1 74  VAL 74  74  74  VAL VAL A . n 
A 1 75  LEU 75  75  75  LEU LEU A . n 
A 1 76  TYR 76  76  76  TYR TYR A . n 
A 1 77  LYS 77  77  77  LYS LYS A . n 
A 1 78  ALA 78  78  78  ALA ALA A . n 
A 1 79  VAL 79  79  79  VAL VAL A . n 
A 1 80  GLU 80  80  80  GLU GLU A . n 
A 1 81  VAL 81  81  81  VAL VAL A . n 
A 1 82  PHE 82  82  82  PHE PHE A . n 
A 1 83  ASP 83  83  83  ASP ASP A . n 
A 1 84  ARG 84  84  84  ARG ARG A . n 
A 1 85  ARG 85  85  85  ARG ARG A . n 
A 1 86  HIS 86  86  86  HIS HIS A . n 
A 1 87  GLU 87  87  87  GLU GLU A . n 
A 1 88  GLU 88  88  88  GLU GLU A . n 
A 1 89  ILE 89  89  89  ILE ILE A . n 
A 1 90  VAL 90  90  90  VAL VAL A . n 
A 1 91  ASP 91  91  91  ASP ASP A . n 
A 1 92  TRP 92  92  92  TRP TRP A . n 
A 1 93  ILE 93  93  93  ILE ILE A . n 
A 1 94  ILE 94  94  94  ILE ILE A . n 
A 1 95  ARG 95  95  95  ARG ARG A . n 
A 1 96  GLU 96  96  96  GLU GLU A . n 
A 1 97  SER 97  97  97  SER SER A . n 
A 1 98  GLY 98  98  98  GLY GLY A . n 
A 1 99  SER 99  99  99  SER SER A . n 
A 1 100 THR 100 100 100 THR THR A . n 
A 1 101 ARG 101 101 101 ARG ARG A . n 
A 1 102 LEU 102 102 102 LEU LEU A . n 
A 1 103 LYS 103 103 103 LYS LYS A . n 
A 1 104 ALA 104 104 104 ALA ALA A . n 
A 1 105 GLU 105 105 105 GLU GLU A . n 
A 1 106 ILE 106 106 106 ILE ILE A . n 
A 1 107 GLU 107 107 107 GLU GLU A . n 
A 1 108 TRP 108 108 108 TRP TRP A . n 
A 1 109 GLY 109 109 109 GLY GLY A . n 
A 1 110 ALA 110 110 110 ALA ALA A . n 
A 1 111 ALA 111 111 111 ALA ALA A . n 
A 1 112 ARG 112 112 112 ARG ARG A . n 
A 1 113 ALA 113 113 113 ALA ALA A . n 
A 1 114 ILE 114 114 114 ILE ILE A . n 
A 1 115 THR 115 115 115 THR THR A . n 
A 1 116 LEU 116 116 116 LEU LEU A . n 
A 1 117 GLU 117 117 117 GLU GLU A . n 
A 1 118 SER 118 118 118 SER SER A . n 
A 1 119 ALA 119 119 119 ALA ALA A . n 
A 1 120 SER 120 120 120 SER SER A . n 
A 1 121 PHE 121 121 121 PHE PHE A . n 
A 1 122 PRO 122 122 122 PRO PRO A . n 
A 1 123 ALA 123 123 123 ALA ALA A . n 
A 1 124 ARG 124 124 124 ARG ARG A . n 
A 1 125 VAL 125 125 125 VAL VAL A . n 
A 1 126 HIS 126 126 126 HIS HIS A . n 
A 1 127 GLY 127 127 127 GLY GLY A . n 
A 1 128 ARG 128 128 128 ARG ARG A . n 
A 1 129 ILE 129 129 129 ILE ILE A . n 
A 1 130 VAL 130 130 130 VAL VAL A . n 
A 1 131 GLU 131 131 131 GLU GLU A . n 
A 1 132 SER 132 132 132 SER SER A . n 
A 1 133 ASP 133 133 133 ASP ASP A . n 
A 1 134 VAL 134 134 134 VAL VAL A . n 
A 1 135 PRO 135 135 135 PRO PRO A . n 
A 1 136 GLY 136 136 136 GLY GLY A . n 
A 1 137 LYS 137 137 137 LYS LYS A . n 
A 1 138 GLU 138 138 138 GLU GLU A . n 
A 1 139 SER 139 139 139 SER SER A . n 
A 1 140 ARG 140 140 140 ARG ARG A . n 
A 1 141 VAL 141 141 141 VAL VAL A . n 
A 1 142 TYR 142 142 142 TYR TYR A . n 
A 1 143 ARG 143 143 143 ARG ARG A . n 
A 1 144 SER 144 144 144 SER SER A . n 
A 1 145 ALA 145 145 145 ALA ALA A . n 
A 1 146 ILE 146 146 146 ILE ILE A . n 
A 1 147 GLY 147 147 147 GLY GLY A . n 
A 1 148 VAL 148 148 148 VAL VAL A . n 
A 1 149 VAL 149 149 149 VAL VAL A . n 
A 1 150 GLY 150 150 150 GLY GLY A . n 
A 1 151 VAL 151 151 151 VAL VAL A . n 
A 1 152 ILE 152 152 152 ILE ILE A . n 
A 1 153 SER 153 153 153 SER SER A . n 
A 1 154 PRO 154 154 154 PRO PRO A . n 
A 1 155 TRP 155 155 155 TRP TRP A . n 
A 1 156 ASN 156 156 156 ASN ASN A . n 
A 1 157 PHE 157 157 157 PHE PHE A . n 
A 1 158 PRO 158 158 158 PRO PRO A . n 
A 1 159 LEU 159 159 159 LEU LEU A . n 
A 1 160 HIS 160 160 160 HIS HIS A . n 
A 1 161 LEU 161 161 161 LEU LEU A . n 
A 1 162 THR 162 162 162 THR THR A . n 
A 1 163 GLN 163 163 163 GLN GLN A . n 
A 1 164 ARG 164 164 164 ARG ARG A . n 
A 1 165 SER 165 165 165 SER SER A . n 
A 1 166 ILE 166 166 166 ILE ILE A . n 
A 1 167 ALA 167 167 167 ALA ALA A . n 
A 1 168 PRO 168 168 168 PRO PRO A . n 
A 1 169 ALA 169 169 169 ALA ALA A . n 
A 1 170 LEU 170 170 170 LEU LEU A . n 
A 1 171 ALA 171 171 171 ALA ALA A . n 
A 1 172 LEU 172 172 172 LEU LEU A . n 
A 1 173 GLY 173 173 173 GLY GLY A . n 
A 1 174 ASN 174 174 174 ASN ASN A . n 
A 1 175 ALA 175 175 175 ALA ALA A . n 
A 1 176 VAL 176 176 176 VAL VAL A . n 
A 1 177 VAL 177 177 177 VAL VAL A . n 
A 1 178 VAL 178 178 178 VAL VAL A . n 
A 1 179 LYS 179 179 179 LYS LYS A . n 
A 1 180 PRO 180 180 180 PRO PRO A . n 
A 1 181 ALA 181 181 181 ALA ALA A . n 
A 1 182 SER 182 182 182 SER SER A . n 
A 1 183 ASP 183 183 183 ASP ASP A . n 
A 1 184 THR 184 184 184 THR THR A . n 
A 1 185 PRO 185 185 185 PRO PRO A . n 
A 1 186 VAL 186 186 186 VAL VAL A . n 
A 1 187 CYS 187 187 187 CYS CYS A . n 
A 1 188 GLY 188 188 188 GLY GLY A . n 
A 1 189 GLY 189 189 189 GLY GLY A . n 
A 1 190 LEU 190 190 190 LEU LEU A . n 
A 1 191 LEU 191 191 191 LEU LEU A . n 
A 1 192 LEU 192 192 192 LEU LEU A . n 
A 1 193 ALA 193 193 193 ALA ALA A . n 
A 1 194 ARG 194 194 194 ARG ARG A . n 
A 1 195 ILE 195 195 195 ILE ILE A . n 
A 1 196 PHE 196 196 196 PHE PHE A . n 
A 1 197 GLU 197 197 197 GLU GLU A . n 
A 1 198 GLU 198 198 198 GLU GLU A . n 
A 1 199 ALA 199 199 199 ALA ALA A . n 
A 1 200 GLY 200 200 200 GLY GLY A . n 
A 1 201 LEU 201 201 201 LEU LEU A . n 
A 1 202 PRO 202 202 202 PRO PRO A . n 
A 1 203 ALA 203 203 203 ALA ALA A . n 
A 1 204 GLY 204 204 204 GLY GLY A . n 
A 1 205 LEU 205 205 205 LEU LEU A . n 
A 1 206 PHE 206 206 206 PHE PHE A . n 
A 1 207 SER 207 207 207 SER SER A . n 
A 1 208 VAL 208 208 208 VAL VAL A . n 
A 1 209 VAL 209 209 209 VAL VAL A . n 
A 1 210 VAL 210 210 210 VAL VAL A . n 
A 1 211 GLY 211 211 211 GLY GLY A . n 
A 1 212 PRO 212 212 212 PRO PRO A . n 
A 1 213 GLY 213 213 213 GLY GLY A . n 
A 1 214 SER 214 214 214 SER SER A . n 
A 1 215 GLU 215 215 215 GLU GLU A . n 
A 1 216 ILE 216 216 216 ILE ILE A . n 
A 1 217 GLY 217 217 217 GLY GLY A . n 
A 1 218 ASP 218 218 218 ASP ASP A . n 
A 1 219 ALA 219 219 219 ALA ALA A . n 
A 1 220 PHE 220 220 220 PHE PHE A . n 
A 1 221 VAL 221 221 221 VAL VAL A . n 
A 1 222 GLU 222 222 222 GLU GLU A . n 
A 1 223 HIS 223 223 223 HIS HIS A . n 
A 1 224 PRO 224 224 224 PRO PRO A . n 
A 1 225 VAL 225 225 225 VAL VAL A . n 
A 1 226 PRO 226 226 226 PRO PRO A . n 
A 1 227 GLY 227 227 227 GLY GLY A . n 
A 1 228 LEU 228 228 228 LEU LEU A . n 
A 1 229 VAL 229 229 229 VAL VAL A . n 
A 1 230 THR 230 230 230 THR THR A . n 
A 1 231 PHE 231 231 231 PHE PHE A . n 
A 1 232 THR 232 232 232 THR THR A . n 
A 1 233 GLY 233 233 233 GLY GLY A . n 
A 1 234 SER 234 234 234 SER SER A . n 
A 1 235 THR 235 235 235 THR THR A . n 
A 1 236 PRO 236 236 236 PRO PRO A . n 
A 1 237 VAL 237 237 237 VAL VAL A . n 
A 1 238 GLY 238 238 238 GLY GLY A . n 
A 1 239 ARG 239 239 239 ARG ARG A . n 
A 1 240 ASN 240 240 240 ASN ASN A . n 
A 1 241 ILE 241 241 241 ILE ILE A . n 
A 1 242 GLY 242 242 242 GLY GLY A . n 
A 1 243 ARG 243 243 243 ARG ARG A . n 
A 1 244 ILE 244 244 244 ILE ILE A . n 
A 1 245 ALA 245 245 245 ALA ALA A . n 
A 1 246 SER 246 246 246 SER SER A . n 
A 1 247 GLY 247 247 247 GLY GLY A . n 
A 1 248 GLY 248 248 248 GLY GLY A . n 
A 1 249 ALA 249 249 249 ALA ALA A . n 
A 1 250 HIS 250 250 250 HIS HIS A . n 
A 1 251 LEU 251 251 251 LEU LEU A . n 
A 1 252 LYS 252 252 252 LYS LYS A . n 
A 1 253 HIS 253 253 253 HIS HIS A . n 
A 1 254 VAL 254 254 254 VAL VAL A . n 
A 1 255 ALA 255 255 255 ALA ALA A . n 
A 1 256 LEU 256 256 256 LEU LEU A . n 
A 1 257 GLU 257 257 257 GLU GLU A . n 
A 1 258 LEU 258 258 258 LEU LEU A . n 
A 1 259 GLY 259 259 259 GLY GLY A . n 
A 1 260 GLY 260 260 260 GLY GLY A . n 
A 1 261 ASN 261 261 261 ASN ASN A . n 
A 1 262 SER 262 262 262 SER SER A . n 
A 1 263 PRO 263 263 263 PRO PRO A . n 
A 1 264 PHE 264 264 264 PHE PHE A . n 
A 1 265 VAL 265 265 265 VAL VAL A . n 
A 1 266 VAL 266 266 266 VAL VAL A . n 
A 1 267 LEU 267 267 267 LEU LEU A . n 
A 1 268 GLY 268 268 268 GLY GLY A . n 
A 1 269 ASP 269 269 269 ASP ASP A . n 
A 1 270 ALA 270 270 270 ALA ALA A . n 
A 1 271 ASP 271 271 271 ASP ASP A . n 
A 1 272 LEU 272 272 272 LEU LEU A . n 
A 1 273 GLU 273 273 273 GLU GLU A . n 
A 1 274 GLN 274 274 274 GLN GLN A . n 
A 1 275 ALA 275 275 275 ALA ALA A . n 
A 1 276 VAL 276 276 276 VAL VAL A . n 
A 1 277 SER 277 277 277 SER SER A . n 
A 1 278 ALA 278 278 278 ALA ALA A . n 
A 1 279 ALA 279 279 279 ALA ALA A . n 
A 1 280 VAL 280 280 280 VAL VAL A . n 
A 1 281 PHE 281 281 281 PHE PHE A . n 
A 1 282 GLY 282 282 282 GLY GLY A . n 
A 1 283 LYS 283 283 283 LYS LYS A . n 
A 1 284 PHE 284 284 284 PHE PHE A . n 
A 1 285 LEU 285 285 285 LEU LEU A . n 
A 1 286 HIS 286 286 286 HIS HIS A . n 
A 1 287 GLN 287 287 ?   ?   ?   A . n 
A 1 288 GLY 288 288 ?   ?   ?   A . n 
A 1 289 GLN 289 289 ?   ?   ?   A . n 
A 1 290 ILE 290 290 ?   ?   ?   A . n 
A 1 291 CYS 291 291 ?   ?   ?   A . n 
A 1 292 MET 292 292 ?   ?   ?   A . n 
A 1 293 ALA 293 293 ?   ?   ?   A . n 
A 1 294 ILE 294 294 294 ILE ILE A . n 
A 1 295 ASN 295 295 295 ASN ASN A . n 
A 1 296 ARG 296 296 296 ARG ARG A . n 
A 1 297 ILE 297 297 297 ILE ILE A . n 
A 1 298 ILE 298 298 298 ILE ILE A . n 
A 1 299 VAL 299 299 299 VAL VAL A . n 
A 1 300 GLU 300 300 300 GLU GLU A . n 
A 1 301 ASP 301 301 301 ASP ASP A . n 
A 1 302 SER 302 302 302 SER SER A . n 
A 1 303 LEU 303 303 303 LEU LEU A . n 
A 1 304 TYR 304 304 304 TYR TYR A . n 
A 1 305 ASP 305 305 305 ASP ASP A . n 
A 1 306 ALA 306 306 306 ALA ALA A . n 
A 1 307 PHE 307 307 307 PHE PHE A . n 
A 1 308 ALA 308 308 308 ALA ALA A . n 
A 1 309 ALA 309 309 309 ALA ALA A . n 
A 1 310 ARG 310 310 310 ARG ARG A . n 
A 1 311 PHE 311 311 311 PHE PHE A . n 
A 1 312 VAL 312 312 312 VAL VAL A . n 
A 1 313 GLU 313 313 313 GLU GLU A . n 
A 1 314 ARG 314 314 314 ARG ARG A . n 
A 1 315 VAL 315 315 315 VAL VAL A . n 
A 1 316 LYS 316 316 316 LYS LYS A . n 
A 1 317 GLY 317 317 317 GLY GLY A . n 
A 1 318 LEU 318 318 318 LEU LEU A . n 
A 1 319 ARG 319 319 319 ARG ARG A . n 
A 1 320 VAL 320 320 320 VAL VAL A . n 
A 1 321 GLY 321 321 321 GLY GLY A . n 
A 1 322 ASP 322 322 322 ASP ASP A . n 
A 1 323 PRO 323 323 323 PRO PRO A . n 
A 1 324 GLN 324 324 324 GLN GLN A . n 
A 1 325 ARG 325 325 325 ARG ARG A . n 
A 1 326 ALA 326 326 326 ALA ALA A . n 
A 1 327 ASP 327 327 327 ASP ASP A . n 
A 1 328 THR 328 328 328 THR THR A . n 
A 1 329 ALA 329 329 329 ALA ALA A . n 
A 1 330 VAL 330 330 330 VAL VAL A . n 
A 1 331 GLY 331 331 331 GLY GLY A . n 
A 1 332 PRO 332 332 332 PRO PRO A . n 
A 1 333 ILE 333 333 333 ILE ILE A . n 
A 1 334 VAL 334 334 334 VAL VAL A . n 
A 1 335 ASN 335 335 335 ASN ASN A . n 
A 1 336 ALA 336 336 336 ALA ALA A . n 
A 1 337 ARG 337 337 337 ARG ARG A . n 
A 1 338 GLN 338 338 338 GLN GLN A . n 
A 1 339 LEU 339 339 339 LEU LEU A . n 
A 1 340 GLU 340 340 340 GLU GLU A . n 
A 1 341 GLY 341 341 341 GLY GLY A . n 
A 1 342 LEU 342 342 342 LEU LEU A . n 
A 1 343 LEU 343 343 343 LEU LEU A . n 
A 1 344 GLU 344 344 344 GLU GLU A . n 
A 1 345 LYS 345 345 345 LYS LYS A . n 
A 1 346 ILE 346 346 346 ILE ILE A . n 
A 1 347 ARG 347 347 347 ARG ARG A . n 
A 1 348 LEU 348 348 348 LEU LEU A . n 
A 1 349 ALA 349 349 349 ALA ALA A . n 
A 1 350 ARG 350 350 350 ARG ARG A . n 
A 1 351 GLN 351 351 351 GLN GLN A . n 
A 1 352 GLU 352 352 352 GLU GLU A . n 
A 1 353 GLY 353 353 353 GLY GLY A . n 
A 1 354 ALA 354 354 354 ALA ALA A . n 
A 1 355 LYS 355 355 355 LYS LYS A . n 
A 1 356 PRO 356 356 356 PRO PRO A . n 
A 1 357 LEU 357 357 357 LEU LEU A . n 
A 1 358 TYR 358 358 358 TYR TYR A . n 
A 1 359 GLU 359 359 359 GLU GLU A . n 
A 1 360 GLY 360 360 360 GLY GLY A . n 
A 1 361 GLY 361 361 361 GLY GLY A . n 
A 1 362 VAL 362 362 362 VAL VAL A . n 
A 1 363 ASP 363 363 363 ASP ASP A . n 
A 1 364 GLY 364 364 364 GLY GLY A . n 
A 1 365 GLN 365 365 365 GLN GLN A . n 
A 1 366 LEU 366 366 366 LEU LEU A . n 
A 1 367 LEU 367 367 367 LEU LEU A . n 
A 1 368 ALA 368 368 368 ALA ALA A . n 
A 1 369 PRO 369 369 369 PRO PRO A . n 
A 1 370 HIS 370 370 370 HIS HIS A . n 
A 1 371 VAL 371 371 371 VAL VAL A . n 
A 1 372 PHE 372 372 372 PHE PHE A . n 
A 1 373 GLY 373 373 373 GLY GLY A . n 
A 1 374 GLU 374 374 374 GLU GLU A . n 
A 1 375 VAL 375 375 375 VAL VAL A . n 
A 1 376 THR 376 376 376 THR THR A . n 
A 1 377 ALA 377 377 377 ALA ALA A . n 
A 1 378 THR 378 378 378 THR THR A . n 
A 1 379 MET 379 379 379 MET MET A . n 
A 1 380 GLU 380 380 380 GLU GLU A . n 
A 1 381 ILE 381 381 381 ILE ILE A . n 
A 1 382 ALA 382 382 382 ALA ALA A . n 
A 1 383 ARG 383 383 383 ARG ARG A . n 
A 1 384 ASP 384 384 384 ASP ASP A . n 
A 1 385 GLU 385 385 385 GLU GLU A . n 
A 1 386 ILE 386 386 386 ILE ILE A . n 
A 1 387 PHE 387 387 387 PHE PHE A . n 
A 1 388 GLY 388 388 388 GLY GLY A . n 
A 1 389 PRO 389 389 389 PRO PRO A . n 
A 1 390 LEU 390 390 390 LEU LEU A . n 
A 1 391 VAL 391 391 391 VAL VAL A . n 
A 1 392 GLY 392 392 392 GLY GLY A . n 
A 1 393 LEU 393 393 393 LEU LEU A . n 
A 1 394 LEU 394 394 394 LEU LEU A . n 
A 1 395 ARG 395 395 395 ARG ARG A . n 
A 1 396 ALA 396 396 396 ALA ALA A . n 
A 1 397 ARG 397 397 397 ARG ARG A . n 
A 1 398 ASP 398 398 398 ASP ASP A . n 
A 1 399 GLU 399 399 399 GLU GLU A . n 
A 1 400 ALA 400 400 400 ALA ALA A . n 
A 1 401 HIS 401 401 401 HIS HIS A . n 
A 1 402 ALA 402 402 402 ALA ALA A . n 
A 1 403 LEU 403 403 403 LEU LEU A . n 
A 1 404 GLU 404 404 404 GLU GLU A . n 
A 1 405 LEU 405 405 405 LEU LEU A . n 
A 1 406 ALA 406 406 406 ALA ALA A . n 
A 1 407 ASN 407 407 407 ASN ASN A . n 
A 1 408 ALA 408 408 408 ALA ALA A . n 
A 1 409 SER 409 409 409 SER SER A . n 
A 1 410 GLU 410 410 ?   ?   ?   A . n 
A 1 411 TYR 411 411 ?   ?   ?   A . n 
A 1 412 GLY 412 412 ?   ?   ?   A . n 
A 1 413 LEU 413 413 413 LEU LEU A . n 
A 1 414 SER 414 414 414 SER SER A . n 
A 1 415 SER 415 415 415 SER SER A . n 
A 1 416 ALA 416 416 416 ALA ALA A . n 
A 1 417 VAL 417 417 417 VAL VAL A . n 
A 1 418 PHE 418 418 418 PHE PHE A . n 
A 1 419 SER 419 419 419 SER SER A . n 
A 1 420 ARG 420 420 420 ARG ARG A . n 
A 1 421 ASP 421 421 421 ASP ASP A . n 
A 1 422 LEU 422 422 422 LEU LEU A . n 
A 1 423 GLU 423 423 423 GLU GLU A . n 
A 1 424 ARG 424 424 424 ARG ARG A . n 
A 1 425 ALA 425 425 425 ALA ALA A . n 
A 1 426 VAL 426 426 426 VAL VAL A . n 
A 1 427 ARG 427 427 427 ARG ARG A . n 
A 1 428 PHE 428 428 428 PHE PHE A . n 
A 1 429 ALA 429 429 429 ALA ALA A . n 
A 1 430 ARG 430 430 430 ARG ARG A . n 
A 1 431 GLN 431 431 431 GLN GLN A . n 
A 1 432 LEU 432 432 432 LEU LEU A . n 
A 1 433 ARG 433 433 433 ARG ARG A . n 
A 1 434 ALA 434 434 434 ALA ALA A . n 
A 1 435 GLY 435 435 435 GLY GLY A . n 
A 1 436 MET 436 436 436 MET MET A . n 
A 1 437 THR 437 437 437 THR THR A . n 
A 1 438 HIS 438 438 438 HIS HIS A . n 
A 1 439 VAL 439 439 439 VAL VAL A . n 
A 1 440 ASN 440 440 440 ASN ASN A . n 
A 1 441 ASP 441 441 441 ASP ASP A . n 
A 1 442 ILE 442 442 ?   ?   ?   A . n 
A 1 443 PRO 443 443 ?   ?   ?   A . n 
A 1 444 VAL 444 444 ?   ?   ?   A . n 
A 1 445 ASN 445 445 ?   ?   ?   A . n 
A 1 446 ASP 446 446 ?   ?   ?   A . n 
A 1 447 GLU 447 447 ?   ?   ?   A . n 
A 1 448 ALA 448 448 ?   ?   ?   A . n 
A 1 449 ASN 449 449 ?   ?   ?   A . n 
A 1 450 ALA 450 450 ?   ?   ?   A . n 
A 1 451 PRO 451 451 ?   ?   ?   A . n 
A 1 452 PHE 452 452 ?   ?   ?   A . n 
A 1 453 GLY 453 453 ?   ?   ?   A . n 
A 1 454 GLY 454 454 ?   ?   ?   A . n 
A 1 455 GLU 455 455 ?   ?   ?   A . n 
A 1 456 LYS 456 456 ?   ?   ?   A . n 
A 1 457 ASN 457 457 ?   ?   ?   A . n 
A 1 458 SER 458 458 ?   ?   ?   A . n 
A 1 459 GLY 459 459 ?   ?   ?   A . n 
A 1 460 LEU 460 460 ?   ?   ?   A . n 
A 1 461 GLY 461 461 461 GLY GLY A . n 
A 1 462 ARG 462 462 462 ARG ARG A . n 
A 1 463 PHE 463 463 463 PHE PHE A . n 
A 1 464 ASN 464 464 464 ASN ASN A . n 
A 1 465 GLY 465 465 465 GLY GLY A . n 
A 1 466 ASP 466 466 466 ASP ASP A . n 
A 1 467 TRP 467 467 467 TRP TRP A . n 
A 1 468 ALA 468 468 468 ALA ALA A . n 
A 1 469 ILE 469 469 469 ILE ILE A . n 
A 1 470 GLU 470 470 470 GLU GLU A . n 
A 1 471 GLU 471 471 471 GLU GLU A . n 
A 1 472 PHE 472 472 472 PHE PHE A . n 
A 1 473 THR 473 473 473 THR THR A . n 
A 1 474 THR 474 474 474 THR THR A . n 
A 1 475 ASP 475 475 475 ASP ASP A . n 
A 1 476 HIS 476 476 476 HIS HIS A . n 
A 1 477 TRP 477 477 477 TRP TRP A . n 
A 1 478 ILE 478 478 478 ILE ILE A . n 
A 1 479 SER 479 479 479 SER SER A . n 
A 1 480 VAL 480 480 480 VAL VAL A . n 
A 1 481 GLN 481 481 481 GLN GLN A . n 
A 1 482 HIS 482 482 482 HIS HIS A . n 
A 1 483 ALA 483 483 ?   ?   ?   A . n 
A 1 484 PRO 484 484 ?   ?   ?   A . n 
A 1 485 ARG 485 485 ?   ?   ?   A . n 
A 1 486 GLN 486 486 ?   ?   ?   A . n 
A 1 487 TYR 487 487 ?   ?   ?   A . n 
A 1 488 PRO 488 488 ?   ?   ?   A . n 
A 1 489 PHE 489 489 ?   ?   ?   A . n 
B 1 1   MET 1   1   ?   ?   ?   B . n 
B 1 2   SER 2   2   ?   ?   ?   B . n 
B 1 3   ASP 3   3   3   ASP ASP B . n 
B 1 4   SER 4   4   4   SER SER B . n 
B 1 5   ARG 5   5   5   ARG ARG B . n 
B 1 6   TYR 6   6   6   TYR TYR B . n 
B 1 7   THR 7   7   7   THR THR B . n 
B 1 8   ASP 8   8   8   ASP ASP B . n 
B 1 9   LEU 9   9   9   LEU LEU B . n 
B 1 10  GLY 10  10  10  GLY GLY B . n 
B 1 11  LEU 11  11  11  LEU LEU B . n 
B 1 12  GLN 12  12  12  GLN GLN B . n 
B 1 13  PRO 13  13  13  PRO PRO B . n 
B 1 14  LEU 14  14  14  LEU LEU B . n 
B 1 15  ALA 15  15  15  ALA ALA B . n 
B 1 16  GLY 16  16  16  GLY GLY B . n 
B 1 17  GLU 17  17  17  GLU GLU B . n 
B 1 18  TRP 18  18  18  TRP TRP B . n 
B 1 19  ARG 19  19  19  ARG ARG B . n 
B 1 20  HIS 20  20  20  HIS HIS B . n 
B 1 21  GLY 21  21  21  GLY GLY B . n 
B 1 22  ARG 22  22  22  ARG ARG B . n 
B 1 23  ALA 23  23  23  ALA ALA B . n 
B 1 24  GLY 24  24  24  GLY GLY B . n 
B 1 25  ARG 25  25  25  ARG ARG B . n 
B 1 26  ARG 26  26  26  ARG ARG B . n 
B 1 27  LEU 27  27  27  LEU LEU B . n 
B 1 28  LYS 28  28  28  LYS LYS B . n 
B 1 29  VAL 29  29  29  VAL VAL B . n 
B 1 30  SER 30  30  30  SER SER B . n 
B 1 31  ASN 31  31  31  ASN ASN B . n 
B 1 32  PRO 32  32  32  PRO PRO B . n 
B 1 33  PHE 33  33  33  PHE PHE B . n 
B 1 34  ASP 34  34  34  ASP ASP B . n 
B 1 35  GLY 35  35  35  GLY GLY B . n 
B 1 36  SER 36  36  36  SER SER B . n 
B 1 37  LEU 37  37  37  LEU LEU B . n 
B 1 38  LEU 38  38  38  LEU LEU B . n 
B 1 39  LEU 39  39  39  LEU LEU B . n 
B 1 40  GLU 40  40  40  GLU GLU B . n 
B 1 41  ILE 41  41  41  ILE ILE B . n 
B 1 42  GLU 42  42  42  GLU GLU B . n 
B 1 43  GLN 43  43  43  GLN GLN B . n 
B 1 44  ALA 44  44  44  ALA ALA B . n 
B 1 45  ASP 45  45  45  ASP ASP B . n 
B 1 46  ARG 46  46  46  ARG ARG B . n 
B 1 47  ASP 47  47  47  ASP ASP B . n 
B 1 48  ASP 48  48  48  ASP ASP B . n 
B 1 49  LEU 49  49  49  LEU LEU B . n 
B 1 50  ASP 50  50  50  ASP ASP B . n 
B 1 51  ALA 51  51  51  ALA ALA B . n 
B 1 52  ALA 52  52  52  ALA ALA B . n 
B 1 53  TYR 53  53  53  TYR TYR B . n 
B 1 54  ALA 54  54  54  ALA ALA B . n 
B 1 55  LYS 55  55  55  LYS LYS B . n 
B 1 56  ALA 56  56  56  ALA ALA B . n 
B 1 57  ALA 57  57  57  ALA ALA B . n 
B 1 58  GLU 58  58  58  GLU GLU B . n 
B 1 59  VAL 59  59  59  VAL VAL B . n 
B 1 60  GLN 60  60  60  GLN GLN B . n 
B 1 61  PRO 61  61  61  PRO PRO B . n 
B 1 62  ALA 62  62  62  ALA ALA B . n 
B 1 63  TRP 63  63  63  TRP TRP B . n 
B 1 64  ALA 64  64  64  ALA ALA B . n 
B 1 65  ALA 65  65  65  ALA ALA B . n 
B 1 66  LEU 66  66  66  LEU LEU B . n 
B 1 67  GLY 67  67  67  GLY GLY B . n 
B 1 68  PRO 68  68  68  PRO PRO B . n 
B 1 69  SER 69  69  69  SER SER B . n 
B 1 70  ALA 70  70  70  ALA ALA B . n 
B 1 71  ARG 71  71  71  ARG ARG B . n 
B 1 72  ALA 72  72  72  ALA ALA B . n 
B 1 73  ALA 73  73  73  ALA ALA B . n 
B 1 74  VAL 74  74  74  VAL VAL B . n 
B 1 75  LEU 75  75  75  LEU LEU B . n 
B 1 76  TYR 76  76  76  TYR TYR B . n 
B 1 77  LYS 77  77  77  LYS LYS B . n 
B 1 78  ALA 78  78  78  ALA ALA B . n 
B 1 79  VAL 79  79  79  VAL VAL B . n 
B 1 80  GLU 80  80  80  GLU GLU B . n 
B 1 81  VAL 81  81  81  VAL VAL B . n 
B 1 82  PHE 82  82  82  PHE PHE B . n 
B 1 83  ASP 83  83  83  ASP ASP B . n 
B 1 84  ARG 84  84  84  ARG ARG B . n 
B 1 85  ARG 85  85  85  ARG ARG B . n 
B 1 86  HIS 86  86  86  HIS HIS B . n 
B 1 87  GLU 87  87  87  GLU GLU B . n 
B 1 88  GLU 88  88  88  GLU GLU B . n 
B 1 89  ILE 89  89  89  ILE ILE B . n 
B 1 90  VAL 90  90  90  VAL VAL B . n 
B 1 91  ASP 91  91  91  ASP ASP B . n 
B 1 92  TRP 92  92  92  TRP TRP B . n 
B 1 93  ILE 93  93  93  ILE ILE B . n 
B 1 94  ILE 94  94  94  ILE ILE B . n 
B 1 95  ARG 95  95  95  ARG ARG B . n 
B 1 96  GLU 96  96  96  GLU GLU B . n 
B 1 97  SER 97  97  97  SER SER B . n 
B 1 98  GLY 98  98  98  GLY GLY B . n 
B 1 99  SER 99  99  99  SER SER B . n 
B 1 100 THR 100 100 100 THR THR B . n 
B 1 101 ARG 101 101 101 ARG ARG B . n 
B 1 102 LEU 102 102 102 LEU LEU B . n 
B 1 103 LYS 103 103 103 LYS LYS B . n 
B 1 104 ALA 104 104 104 ALA ALA B . n 
B 1 105 GLU 105 105 105 GLU GLU B . n 
B 1 106 ILE 106 106 106 ILE ILE B . n 
B 1 107 GLU 107 107 107 GLU GLU B . n 
B 1 108 TRP 108 108 108 TRP TRP B . n 
B 1 109 GLY 109 109 109 GLY GLY B . n 
B 1 110 ALA 110 110 110 ALA ALA B . n 
B 1 111 ALA 111 111 111 ALA ALA B . n 
B 1 112 ARG 112 112 112 ARG ARG B . n 
B 1 113 ALA 113 113 113 ALA ALA B . n 
B 1 114 ILE 114 114 114 ILE ILE B . n 
B 1 115 THR 115 115 115 THR THR B . n 
B 1 116 LEU 116 116 116 LEU LEU B . n 
B 1 117 GLU 117 117 117 GLU GLU B . n 
B 1 118 SER 118 118 118 SER SER B . n 
B 1 119 ALA 119 119 119 ALA ALA B . n 
B 1 120 SER 120 120 120 SER SER B . n 
B 1 121 PHE 121 121 121 PHE PHE B . n 
B 1 122 PRO 122 122 122 PRO PRO B . n 
B 1 123 ALA 123 123 123 ALA ALA B . n 
B 1 124 ARG 124 124 124 ARG ARG B . n 
B 1 125 VAL 125 125 125 VAL VAL B . n 
B 1 126 HIS 126 126 126 HIS HIS B . n 
B 1 127 GLY 127 127 127 GLY GLY B . n 
B 1 128 ARG 128 128 128 ARG ARG B . n 
B 1 129 ILE 129 129 129 ILE ILE B . n 
B 1 130 VAL 130 130 130 VAL VAL B . n 
B 1 131 GLU 131 131 131 GLU GLU B . n 
B 1 132 SER 132 132 132 SER SER B . n 
B 1 133 ASP 133 133 133 ASP ASP B . n 
B 1 134 VAL 134 134 134 VAL VAL B . n 
B 1 135 PRO 135 135 135 PRO PRO B . n 
B 1 136 GLY 136 136 136 GLY GLY B . n 
B 1 137 LYS 137 137 137 LYS LYS B . n 
B 1 138 GLU 138 138 138 GLU GLU B . n 
B 1 139 SER 139 139 139 SER SER B . n 
B 1 140 ARG 140 140 140 ARG ARG B . n 
B 1 141 VAL 141 141 141 VAL VAL B . n 
B 1 142 TYR 142 142 142 TYR TYR B . n 
B 1 143 ARG 143 143 143 ARG ARG B . n 
B 1 144 SER 144 144 144 SER SER B . n 
B 1 145 ALA 145 145 145 ALA ALA B . n 
B 1 146 ILE 146 146 146 ILE ILE B . n 
B 1 147 GLY 147 147 147 GLY GLY B . n 
B 1 148 VAL 148 148 148 VAL VAL B . n 
B 1 149 VAL 149 149 149 VAL VAL B . n 
B 1 150 GLY 150 150 150 GLY GLY B . n 
B 1 151 VAL 151 151 151 VAL VAL B . n 
B 1 152 ILE 152 152 152 ILE ILE B . n 
B 1 153 SER 153 153 153 SER SER B . n 
B 1 154 PRO 154 154 154 PRO PRO B . n 
B 1 155 TRP 155 155 155 TRP TRP B . n 
B 1 156 ASN 156 156 156 ASN ASN B . n 
B 1 157 PHE 157 157 157 PHE PHE B . n 
B 1 158 PRO 158 158 158 PRO PRO B . n 
B 1 159 LEU 159 159 159 LEU LEU B . n 
B 1 160 HIS 160 160 160 HIS HIS B . n 
B 1 161 LEU 161 161 161 LEU LEU B . n 
B 1 162 THR 162 162 162 THR THR B . n 
B 1 163 GLN 163 163 163 GLN GLN B . n 
B 1 164 ARG 164 164 164 ARG ARG B . n 
B 1 165 SER 165 165 165 SER SER B . n 
B 1 166 ILE 166 166 166 ILE ILE B . n 
B 1 167 ALA 167 167 167 ALA ALA B . n 
B 1 168 PRO 168 168 168 PRO PRO B . n 
B 1 169 ALA 169 169 169 ALA ALA B . n 
B 1 170 LEU 170 170 170 LEU LEU B . n 
B 1 171 ALA 171 171 171 ALA ALA B . n 
B 1 172 LEU 172 172 172 LEU LEU B . n 
B 1 173 GLY 173 173 173 GLY GLY B . n 
B 1 174 ASN 174 174 174 ASN ASN B . n 
B 1 175 ALA 175 175 175 ALA ALA B . n 
B 1 176 VAL 176 176 176 VAL VAL B . n 
B 1 177 VAL 177 177 177 VAL VAL B . n 
B 1 178 VAL 178 178 178 VAL VAL B . n 
B 1 179 LYS 179 179 179 LYS LYS B . n 
B 1 180 PRO 180 180 180 PRO PRO B . n 
B 1 181 ALA 181 181 181 ALA ALA B . n 
B 1 182 SER 182 182 182 SER SER B . n 
B 1 183 ASP 183 183 183 ASP ASP B . n 
B 1 184 THR 184 184 184 THR THR B . n 
B 1 185 PRO 185 185 185 PRO PRO B . n 
B 1 186 VAL 186 186 186 VAL VAL B . n 
B 1 187 CYS 187 187 187 CYS CYS B . n 
B 1 188 GLY 188 188 188 GLY GLY B . n 
B 1 189 GLY 189 189 189 GLY GLY B . n 
B 1 190 LEU 190 190 190 LEU LEU B . n 
B 1 191 LEU 191 191 191 LEU LEU B . n 
B 1 192 LEU 192 192 192 LEU LEU B . n 
B 1 193 ALA 193 193 193 ALA ALA B . n 
B 1 194 ARG 194 194 194 ARG ARG B . n 
B 1 195 ILE 195 195 195 ILE ILE B . n 
B 1 196 PHE 196 196 196 PHE PHE B . n 
B 1 197 GLU 197 197 197 GLU GLU B . n 
B 1 198 GLU 198 198 198 GLU GLU B . n 
B 1 199 ALA 199 199 199 ALA ALA B . n 
B 1 200 GLY 200 200 200 GLY GLY B . n 
B 1 201 LEU 201 201 201 LEU LEU B . n 
B 1 202 PRO 202 202 202 PRO PRO B . n 
B 1 203 ALA 203 203 203 ALA ALA B . n 
B 1 204 GLY 204 204 204 GLY GLY B . n 
B 1 205 LEU 205 205 205 LEU LEU B . n 
B 1 206 PHE 206 206 206 PHE PHE B . n 
B 1 207 SER 207 207 207 SER SER B . n 
B 1 208 VAL 208 208 208 VAL VAL B . n 
B 1 209 VAL 209 209 209 VAL VAL B . n 
B 1 210 VAL 210 210 210 VAL VAL B . n 
B 1 211 GLY 211 211 211 GLY GLY B . n 
B 1 212 PRO 212 212 212 PRO PRO B . n 
B 1 213 GLY 213 213 213 GLY GLY B . n 
B 1 214 SER 214 214 214 SER SER B . n 
B 1 215 GLU 215 215 215 GLU GLU B . n 
B 1 216 ILE 216 216 216 ILE ILE B . n 
B 1 217 GLY 217 217 217 GLY GLY B . n 
B 1 218 ASP 218 218 218 ASP ASP B . n 
B 1 219 ALA 219 219 219 ALA ALA B . n 
B 1 220 PHE 220 220 220 PHE PHE B . n 
B 1 221 VAL 221 221 221 VAL VAL B . n 
B 1 222 GLU 222 222 222 GLU GLU B . n 
B 1 223 HIS 223 223 223 HIS HIS B . n 
B 1 224 PRO 224 224 224 PRO PRO B . n 
B 1 225 VAL 225 225 225 VAL VAL B . n 
B 1 226 PRO 226 226 226 PRO PRO B . n 
B 1 227 GLY 227 227 227 GLY GLY B . n 
B 1 228 LEU 228 228 228 LEU LEU B . n 
B 1 229 VAL 229 229 229 VAL VAL B . n 
B 1 230 THR 230 230 230 THR THR B . n 
B 1 231 PHE 231 231 231 PHE PHE B . n 
B 1 232 THR 232 232 232 THR THR B . n 
B 1 233 GLY 233 233 233 GLY GLY B . n 
B 1 234 SER 234 234 234 SER SER B . n 
B 1 235 THR 235 235 235 THR THR B . n 
B 1 236 PRO 236 236 236 PRO PRO B . n 
B 1 237 VAL 237 237 237 VAL VAL B . n 
B 1 238 GLY 238 238 238 GLY GLY B . n 
B 1 239 ARG 239 239 239 ARG ARG B . n 
B 1 240 ASN 240 240 240 ASN ASN B . n 
B 1 241 ILE 241 241 241 ILE ILE B . n 
B 1 242 GLY 242 242 242 GLY GLY B . n 
B 1 243 ARG 243 243 243 ARG ARG B . n 
B 1 244 ILE 244 244 244 ILE ILE B . n 
B 1 245 ALA 245 245 245 ALA ALA B . n 
B 1 246 SER 246 246 246 SER SER B . n 
B 1 247 GLY 247 247 247 GLY GLY B . n 
B 1 248 GLY 248 248 248 GLY GLY B . n 
B 1 249 ALA 249 249 249 ALA ALA B . n 
B 1 250 HIS 250 250 250 HIS HIS B . n 
B 1 251 LEU 251 251 251 LEU LEU B . n 
B 1 252 LYS 252 252 252 LYS LYS B . n 
B 1 253 HIS 253 253 253 HIS HIS B . n 
B 1 254 VAL 254 254 254 VAL VAL B . n 
B 1 255 ALA 255 255 255 ALA ALA B . n 
B 1 256 LEU 256 256 256 LEU LEU B . n 
B 1 257 GLU 257 257 257 GLU GLU B . n 
B 1 258 LEU 258 258 258 LEU LEU B . n 
B 1 259 GLY 259 259 259 GLY GLY B . n 
B 1 260 GLY 260 260 260 GLY GLY B . n 
B 1 261 ASN 261 261 261 ASN ASN B . n 
B 1 262 SER 262 262 262 SER SER B . n 
B 1 263 PRO 263 263 263 PRO PRO B . n 
B 1 264 PHE 264 264 264 PHE PHE B . n 
B 1 265 VAL 265 265 265 VAL VAL B . n 
B 1 266 VAL 266 266 266 VAL VAL B . n 
B 1 267 LEU 267 267 267 LEU LEU B . n 
B 1 268 GLY 268 268 268 GLY GLY B . n 
B 1 269 ASP 269 269 269 ASP ASP B . n 
B 1 270 ALA 270 270 270 ALA ALA B . n 
B 1 271 ASP 271 271 271 ASP ASP B . n 
B 1 272 LEU 272 272 272 LEU LEU B . n 
B 1 273 GLU 273 273 273 GLU GLU B . n 
B 1 274 GLN 274 274 274 GLN GLN B . n 
B 1 275 ALA 275 275 275 ALA ALA B . n 
B 1 276 VAL 276 276 276 VAL VAL B . n 
B 1 277 SER 277 277 277 SER SER B . n 
B 1 278 ALA 278 278 278 ALA ALA B . n 
B 1 279 ALA 279 279 279 ALA ALA B . n 
B 1 280 VAL 280 280 280 VAL VAL B . n 
B 1 281 PHE 281 281 281 PHE PHE B . n 
B 1 282 GLY 282 282 282 GLY GLY B . n 
B 1 283 LYS 283 283 283 LYS LYS B . n 
B 1 284 PHE 284 284 284 PHE PHE B . n 
B 1 285 LEU 285 285 ?   ?   ?   B . n 
B 1 286 HIS 286 286 ?   ?   ?   B . n 
B 1 287 GLN 287 287 ?   ?   ?   B . n 
B 1 288 GLY 288 288 ?   ?   ?   B . n 
B 1 289 GLN 289 289 ?   ?   ?   B . n 
B 1 290 ILE 290 290 290 ILE ILE B . n 
B 1 291 CYS 291 291 291 CYS CYS B . n 
B 1 292 MET 292 292 292 MET MET B . n 
B 1 293 ALA 293 293 293 ALA ALA B . n 
B 1 294 ILE 294 294 294 ILE ILE B . n 
B 1 295 ASN 295 295 295 ASN ASN B . n 
B 1 296 ARG 296 296 296 ARG ARG B . n 
B 1 297 ILE 297 297 297 ILE ILE B . n 
B 1 298 ILE 298 298 298 ILE ILE B . n 
B 1 299 VAL 299 299 299 VAL VAL B . n 
B 1 300 GLU 300 300 300 GLU GLU B . n 
B 1 301 ASP 301 301 301 ASP ASP B . n 
B 1 302 SER 302 302 302 SER SER B . n 
B 1 303 LEU 303 303 303 LEU LEU B . n 
B 1 304 TYR 304 304 304 TYR TYR B . n 
B 1 305 ASP 305 305 305 ASP ASP B . n 
B 1 306 ALA 306 306 306 ALA ALA B . n 
B 1 307 PHE 307 307 307 PHE PHE B . n 
B 1 308 ALA 308 308 308 ALA ALA B . n 
B 1 309 ALA 309 309 309 ALA ALA B . n 
B 1 310 ARG 310 310 310 ARG ARG B . n 
B 1 311 PHE 311 311 311 PHE PHE B . n 
B 1 312 VAL 312 312 312 VAL VAL B . n 
B 1 313 GLU 313 313 313 GLU GLU B . n 
B 1 314 ARG 314 314 314 ARG ARG B . n 
B 1 315 VAL 315 315 315 VAL VAL B . n 
B 1 316 LYS 316 316 316 LYS LYS B . n 
B 1 317 GLY 317 317 317 GLY GLY B . n 
B 1 318 LEU 318 318 318 LEU LEU B . n 
B 1 319 ARG 319 319 319 ARG ARG B . n 
B 1 320 VAL 320 320 320 VAL VAL B . n 
B 1 321 GLY 321 321 321 GLY GLY B . n 
B 1 322 ASP 322 322 322 ASP ASP B . n 
B 1 323 PRO 323 323 323 PRO PRO B . n 
B 1 324 GLN 324 324 324 GLN GLN B . n 
B 1 325 ARG 325 325 325 ARG ARG B . n 
B 1 326 ALA 326 326 326 ALA ALA B . n 
B 1 327 ASP 327 327 327 ASP ASP B . n 
B 1 328 THR 328 328 328 THR THR B . n 
B 1 329 ALA 329 329 329 ALA ALA B . n 
B 1 330 VAL 330 330 330 VAL VAL B . n 
B 1 331 GLY 331 331 331 GLY GLY B . n 
B 1 332 PRO 332 332 332 PRO PRO B . n 
B 1 333 ILE 333 333 333 ILE ILE B . n 
B 1 334 VAL 334 334 334 VAL VAL B . n 
B 1 335 ASN 335 335 335 ASN ASN B . n 
B 1 336 ALA 336 336 336 ALA ALA B . n 
B 1 337 ARG 337 337 337 ARG ARG B . n 
B 1 338 GLN 338 338 338 GLN GLN B . n 
B 1 339 LEU 339 339 339 LEU LEU B . n 
B 1 340 GLU 340 340 340 GLU GLU B . n 
B 1 341 GLY 341 341 341 GLY GLY B . n 
B 1 342 LEU 342 342 342 LEU LEU B . n 
B 1 343 LEU 343 343 343 LEU LEU B . n 
B 1 344 GLU 344 344 344 GLU GLU B . n 
B 1 345 LYS 345 345 345 LYS LYS B . n 
B 1 346 ILE 346 346 346 ILE ILE B . n 
B 1 347 ARG 347 347 347 ARG ARG B . n 
B 1 348 LEU 348 348 348 LEU LEU B . n 
B 1 349 ALA 349 349 349 ALA ALA B . n 
B 1 350 ARG 350 350 350 ARG ARG B . n 
B 1 351 GLN 351 351 351 GLN GLN B . n 
B 1 352 GLU 352 352 352 GLU GLU B . n 
B 1 353 GLY 353 353 353 GLY GLY B . n 
B 1 354 ALA 354 354 354 ALA ALA B . n 
B 1 355 LYS 355 355 355 LYS LYS B . n 
B 1 356 PRO 356 356 356 PRO PRO B . n 
B 1 357 LEU 357 357 357 LEU LEU B . n 
B 1 358 TYR 358 358 358 TYR TYR B . n 
B 1 359 GLU 359 359 359 GLU GLU B . n 
B 1 360 GLY 360 360 360 GLY GLY B . n 
B 1 361 GLY 361 361 361 GLY GLY B . n 
B 1 362 VAL 362 362 362 VAL VAL B . n 
B 1 363 ASP 363 363 363 ASP ASP B . n 
B 1 364 GLY 364 364 364 GLY GLY B . n 
B 1 365 GLN 365 365 365 GLN GLN B . n 
B 1 366 LEU 366 366 366 LEU LEU B . n 
B 1 367 LEU 367 367 367 LEU LEU B . n 
B 1 368 ALA 368 368 368 ALA ALA B . n 
B 1 369 PRO 369 369 369 PRO PRO B . n 
B 1 370 HIS 370 370 370 HIS HIS B . n 
B 1 371 VAL 371 371 371 VAL VAL B . n 
B 1 372 PHE 372 372 372 PHE PHE B . n 
B 1 373 GLY 373 373 373 GLY GLY B . n 
B 1 374 GLU 374 374 374 GLU GLU B . n 
B 1 375 VAL 375 375 375 VAL VAL B . n 
B 1 376 THR 376 376 376 THR THR B . n 
B 1 377 ALA 377 377 377 ALA ALA B . n 
B 1 378 THR 378 378 378 THR THR B . n 
B 1 379 MET 379 379 379 MET MET B . n 
B 1 380 GLU 380 380 380 GLU GLU B . n 
B 1 381 ILE 381 381 381 ILE ILE B . n 
B 1 382 ALA 382 382 382 ALA ALA B . n 
B 1 383 ARG 383 383 383 ARG ARG B . n 
B 1 384 ASP 384 384 384 ASP ASP B . n 
B 1 385 GLU 385 385 385 GLU GLU B . n 
B 1 386 ILE 386 386 386 ILE ILE B . n 
B 1 387 PHE 387 387 387 PHE PHE B . n 
B 1 388 GLY 388 388 388 GLY GLY B . n 
B 1 389 PRO 389 389 389 PRO PRO B . n 
B 1 390 LEU 390 390 390 LEU LEU B . n 
B 1 391 VAL 391 391 391 VAL VAL B . n 
B 1 392 GLY 392 392 392 GLY GLY B . n 
B 1 393 LEU 393 393 393 LEU LEU B . n 
B 1 394 LEU 394 394 394 LEU LEU B . n 
B 1 395 ARG 395 395 395 ARG ARG B . n 
B 1 396 ALA 396 396 396 ALA ALA B . n 
B 1 397 ARG 397 397 397 ARG ARG B . n 
B 1 398 ASP 398 398 398 ASP ASP B . n 
B 1 399 GLU 399 399 399 GLU GLU B . n 
B 1 400 ALA 400 400 400 ALA ALA B . n 
B 1 401 HIS 401 401 401 HIS HIS B . n 
B 1 402 ALA 402 402 402 ALA ALA B . n 
B 1 403 LEU 403 403 403 LEU LEU B . n 
B 1 404 GLU 404 404 404 GLU GLU B . n 
B 1 405 LEU 405 405 405 LEU LEU B . n 
B 1 406 ALA 406 406 406 ALA ALA B . n 
B 1 407 ASN 407 407 407 ASN ASN B . n 
B 1 408 ALA 408 408 408 ALA ALA B . n 
B 1 409 SER 409 409 409 SER SER B . n 
B 1 410 GLU 410 410 410 GLU GLU B . n 
B 1 411 TYR 411 411 411 TYR TYR B . n 
B 1 412 GLY 412 412 412 GLY GLY B . n 
B 1 413 LEU 413 413 413 LEU LEU B . n 
B 1 414 SER 414 414 414 SER SER B . n 
B 1 415 SER 415 415 415 SER SER B . n 
B 1 416 ALA 416 416 416 ALA ALA B . n 
B 1 417 VAL 417 417 417 VAL VAL B . n 
B 1 418 PHE 418 418 418 PHE PHE B . n 
B 1 419 SER 419 419 419 SER SER B . n 
B 1 420 ARG 420 420 420 ARG ARG B . n 
B 1 421 ASP 421 421 421 ASP ASP B . n 
B 1 422 LEU 422 422 422 LEU LEU B . n 
B 1 423 GLU 423 423 423 GLU GLU B . n 
B 1 424 ARG 424 424 424 ARG ARG B . n 
B 1 425 ALA 425 425 425 ALA ALA B . n 
B 1 426 VAL 426 426 426 VAL VAL B . n 
B 1 427 ARG 427 427 427 ARG ARG B . n 
B 1 428 PHE 428 428 428 PHE PHE B . n 
B 1 429 ALA 429 429 429 ALA ALA B . n 
B 1 430 ARG 430 430 430 ARG ARG B . n 
B 1 431 GLN 431 431 431 GLN GLN B . n 
B 1 432 LEU 432 432 432 LEU LEU B . n 
B 1 433 ARG 433 433 433 ARG ARG B . n 
B 1 434 ALA 434 434 434 ALA ALA B . n 
B 1 435 GLY 435 435 435 GLY GLY B . n 
B 1 436 MET 436 436 436 MET MET B . n 
B 1 437 THR 437 437 437 THR THR B . n 
B 1 438 HIS 438 438 438 HIS HIS B . n 
B 1 439 VAL 439 439 439 VAL VAL B . n 
B 1 440 ASN 440 440 440 ASN ASN B . n 
B 1 441 ASP 441 441 441 ASP ASP B . n 
B 1 442 ILE 442 442 442 ILE ILE B . n 
B 1 443 PRO 443 443 443 PRO PRO B . n 
B 1 444 VAL 444 444 ?   ?   ?   B . n 
B 1 445 ASN 445 445 ?   ?   ?   B . n 
B 1 446 ASP 446 446 ?   ?   ?   B . n 
B 1 447 GLU 447 447 ?   ?   ?   B . n 
B 1 448 ALA 448 448 ?   ?   ?   B . n 
B 1 449 ASN 449 449 ?   ?   ?   B . n 
B 1 450 ALA 450 450 ?   ?   ?   B . n 
B 1 451 PRO 451 451 ?   ?   ?   B . n 
B 1 452 PHE 452 452 ?   ?   ?   B . n 
B 1 453 GLY 453 453 ?   ?   ?   B . n 
B 1 454 GLY 454 454 ?   ?   ?   B . n 
B 1 455 GLU 455 455 ?   ?   ?   B . n 
B 1 456 LYS 456 456 ?   ?   ?   B . n 
B 1 457 ASN 457 457 ?   ?   ?   B . n 
B 1 458 SER 458 458 ?   ?   ?   B . n 
B 1 459 GLY 459 459 459 GLY GLY B . n 
B 1 460 LEU 460 460 460 LEU LEU B . n 
B 1 461 GLY 461 461 461 GLY GLY B . n 
B 1 462 ARG 462 462 462 ARG ARG B . n 
B 1 463 PHE 463 463 463 PHE PHE B . n 
B 1 464 ASN 464 464 464 ASN ASN B . n 
B 1 465 GLY 465 465 465 GLY GLY B . n 
B 1 466 ASP 466 466 466 ASP ASP B . n 
B 1 467 TRP 467 467 467 TRP TRP B . n 
B 1 468 ALA 468 468 468 ALA ALA B . n 
B 1 469 ILE 469 469 469 ILE ILE B . n 
B 1 470 GLU 470 470 470 GLU GLU B . n 
B 1 471 GLU 471 471 471 GLU GLU B . n 
B 1 472 PHE 472 472 472 PHE PHE B . n 
B 1 473 THR 473 473 473 THR THR B . n 
B 1 474 THR 474 474 474 THR THR B . n 
B 1 475 ASP 475 475 475 ASP ASP B . n 
B 1 476 HIS 476 476 476 HIS HIS B . n 
B 1 477 TRP 477 477 477 TRP TRP B . n 
B 1 478 ILE 478 478 478 ILE ILE B . n 
B 1 479 SER 479 479 479 SER SER B . n 
B 1 480 VAL 480 480 480 VAL VAL B . n 
B 1 481 GLN 481 481 481 GLN GLN B . n 
B 1 482 HIS 482 482 482 HIS HIS B . n 
B 1 483 ALA 483 483 483 ALA ALA B . n 
B 1 484 PRO 484 484 484 PRO PRO B . n 
B 1 485 ARG 485 485 485 ARG ARG B . n 
B 1 486 GLN 486 486 486 GLN GLN B . n 
B 1 487 TYR 487 487 487 TYR TYR B . n 
B 1 488 PRO 488 488 488 PRO PRO B . n 
B 1 489 PHE 489 489 ?   ?   ?   B . n 
C 1 1   MET 1   1   ?   ?   ?   C . n 
C 1 2   SER 2   2   2   SER SER C . n 
C 1 3   ASP 3   3   3   ASP ASP C . n 
C 1 4   SER 4   4   4   SER SER C . n 
C 1 5   ARG 5   5   5   ARG ARG C . n 
C 1 6   TYR 6   6   6   TYR TYR C . n 
C 1 7   THR 7   7   7   THR THR C . n 
C 1 8   ASP 8   8   8   ASP ASP C . n 
C 1 9   LEU 9   9   9   LEU LEU C . n 
C 1 10  GLY 10  10  10  GLY GLY C . n 
C 1 11  LEU 11  11  11  LEU LEU C . n 
C 1 12  GLN 12  12  12  GLN GLN C . n 
C 1 13  PRO 13  13  13  PRO PRO C . n 
C 1 14  LEU 14  14  14  LEU LEU C . n 
C 1 15  ALA 15  15  15  ALA ALA C . n 
C 1 16  GLY 16  16  16  GLY GLY C . n 
C 1 17  GLU 17  17  17  GLU GLU C . n 
C 1 18  TRP 18  18  18  TRP TRP C . n 
C 1 19  ARG 19  19  19  ARG ARG C . n 
C 1 20  HIS 20  20  20  HIS HIS C . n 
C 1 21  GLY 21  21  21  GLY GLY C . n 
C 1 22  ARG 22  22  22  ARG ARG C . n 
C 1 23  ALA 23  23  23  ALA ALA C . n 
C 1 24  GLY 24  24  24  GLY GLY C . n 
C 1 25  ARG 25  25  25  ARG ARG C . n 
C 1 26  ARG 26  26  26  ARG ARG C . n 
C 1 27  LEU 27  27  27  LEU LEU C . n 
C 1 28  LYS 28  28  28  LYS LYS C . n 
C 1 29  VAL 29  29  29  VAL VAL C . n 
C 1 30  SER 30  30  30  SER SER C . n 
C 1 31  ASN 31  31  31  ASN ASN C . n 
C 1 32  PRO 32  32  32  PRO PRO C . n 
C 1 33  PHE 33  33  33  PHE PHE C . n 
C 1 34  ASP 34  34  34  ASP ASP C . n 
C 1 35  GLY 35  35  35  GLY GLY C . n 
C 1 36  SER 36  36  36  SER SER C . n 
C 1 37  LEU 37  37  37  LEU LEU C . n 
C 1 38  LEU 38  38  38  LEU LEU C . n 
C 1 39  LEU 39  39  39  LEU LEU C . n 
C 1 40  GLU 40  40  40  GLU GLU C . n 
C 1 41  ILE 41  41  41  ILE ILE C . n 
C 1 42  GLU 42  42  42  GLU GLU C . n 
C 1 43  GLN 43  43  43  GLN GLN C . n 
C 1 44  ALA 44  44  44  ALA ALA C . n 
C 1 45  ASP 45  45  45  ASP ASP C . n 
C 1 46  ARG 46  46  46  ARG ARG C . n 
C 1 47  ASP 47  47  47  ASP ASP C . n 
C 1 48  ASP 48  48  48  ASP ASP C . n 
C 1 49  LEU 49  49  49  LEU LEU C . n 
C 1 50  ASP 50  50  50  ASP ASP C . n 
C 1 51  ALA 51  51  51  ALA ALA C . n 
C 1 52  ALA 52  52  52  ALA ALA C . n 
C 1 53  TYR 53  53  53  TYR TYR C . n 
C 1 54  ALA 54  54  54  ALA ALA C . n 
C 1 55  LYS 55  55  55  LYS LYS C . n 
C 1 56  ALA 56  56  56  ALA ALA C . n 
C 1 57  ALA 57  57  57  ALA ALA C . n 
C 1 58  GLU 58  58  58  GLU GLU C . n 
C 1 59  VAL 59  59  59  VAL VAL C . n 
C 1 60  GLN 60  60  60  GLN GLN C . n 
C 1 61  PRO 61  61  61  PRO PRO C . n 
C 1 62  ALA 62  62  62  ALA ALA C . n 
C 1 63  TRP 63  63  63  TRP TRP C . n 
C 1 64  ALA 64  64  64  ALA ALA C . n 
C 1 65  ALA 65  65  65  ALA ALA C . n 
C 1 66  LEU 66  66  66  LEU LEU C . n 
C 1 67  GLY 67  67  67  GLY GLY C . n 
C 1 68  PRO 68  68  68  PRO PRO C . n 
C 1 69  SER 69  69  69  SER SER C . n 
C 1 70  ALA 70  70  70  ALA ALA C . n 
C 1 71  ARG 71  71  71  ARG ARG C . n 
C 1 72  ALA 72  72  72  ALA ALA C . n 
C 1 73  ALA 73  73  73  ALA ALA C . n 
C 1 74  VAL 74  74  74  VAL VAL C . n 
C 1 75  LEU 75  75  75  LEU LEU C . n 
C 1 76  TYR 76  76  76  TYR TYR C . n 
C 1 77  LYS 77  77  77  LYS LYS C . n 
C 1 78  ALA 78  78  78  ALA ALA C . n 
C 1 79  VAL 79  79  79  VAL VAL C . n 
C 1 80  GLU 80  80  80  GLU GLU C . n 
C 1 81  VAL 81  81  81  VAL VAL C . n 
C 1 82  PHE 82  82  82  PHE PHE C . n 
C 1 83  ASP 83  83  83  ASP ASP C . n 
C 1 84  ARG 84  84  84  ARG ARG C . n 
C 1 85  ARG 85  85  85  ARG ARG C . n 
C 1 86  HIS 86  86  86  HIS HIS C . n 
C 1 87  GLU 87  87  87  GLU GLU C . n 
C 1 88  GLU 88  88  88  GLU GLU C . n 
C 1 89  ILE 89  89  89  ILE ILE C . n 
C 1 90  VAL 90  90  90  VAL VAL C . n 
C 1 91  ASP 91  91  91  ASP ASP C . n 
C 1 92  TRP 92  92  92  TRP TRP C . n 
C 1 93  ILE 93  93  93  ILE ILE C . n 
C 1 94  ILE 94  94  94  ILE ILE C . n 
C 1 95  ARG 95  95  95  ARG ARG C . n 
C 1 96  GLU 96  96  96  GLU GLU C . n 
C 1 97  SER 97  97  97  SER SER C . n 
C 1 98  GLY 98  98  98  GLY GLY C . n 
C 1 99  SER 99  99  99  SER SER C . n 
C 1 100 THR 100 100 100 THR THR C . n 
C 1 101 ARG 101 101 101 ARG ARG C . n 
C 1 102 LEU 102 102 102 LEU LEU C . n 
C 1 103 LYS 103 103 103 LYS LYS C . n 
C 1 104 ALA 104 104 104 ALA ALA C . n 
C 1 105 GLU 105 105 105 GLU GLU C . n 
C 1 106 ILE 106 106 106 ILE ILE C . n 
C 1 107 GLU 107 107 107 GLU GLU C . n 
C 1 108 TRP 108 108 108 TRP TRP C . n 
C 1 109 GLY 109 109 109 GLY GLY C . n 
C 1 110 ALA 110 110 110 ALA ALA C . n 
C 1 111 ALA 111 111 111 ALA ALA C . n 
C 1 112 ARG 112 112 112 ARG ARG C . n 
C 1 113 ALA 113 113 113 ALA ALA C . n 
C 1 114 ILE 114 114 114 ILE ILE C . n 
C 1 115 THR 115 115 115 THR THR C . n 
C 1 116 LEU 116 116 116 LEU LEU C . n 
C 1 117 GLU 117 117 117 GLU GLU C . n 
C 1 118 SER 118 118 118 SER SER C . n 
C 1 119 ALA 119 119 119 ALA ALA C . n 
C 1 120 SER 120 120 120 SER SER C . n 
C 1 121 PHE 121 121 121 PHE PHE C . n 
C 1 122 PRO 122 122 122 PRO PRO C . n 
C 1 123 ALA 123 123 123 ALA ALA C . n 
C 1 124 ARG 124 124 124 ARG ARG C . n 
C 1 125 VAL 125 125 125 VAL VAL C . n 
C 1 126 HIS 126 126 126 HIS HIS C . n 
C 1 127 GLY 127 127 127 GLY GLY C . n 
C 1 128 ARG 128 128 128 ARG ARG C . n 
C 1 129 ILE 129 129 129 ILE ILE C . n 
C 1 130 VAL 130 130 130 VAL VAL C . n 
C 1 131 GLU 131 131 131 GLU GLU C . n 
C 1 132 SER 132 132 132 SER SER C . n 
C 1 133 ASP 133 133 133 ASP ASP C . n 
C 1 134 VAL 134 134 134 VAL VAL C . n 
C 1 135 PRO 135 135 135 PRO PRO C . n 
C 1 136 GLY 136 136 136 GLY GLY C . n 
C 1 137 LYS 137 137 137 LYS LYS C . n 
C 1 138 GLU 138 138 138 GLU GLU C . n 
C 1 139 SER 139 139 139 SER SER C . n 
C 1 140 ARG 140 140 140 ARG ARG C . n 
C 1 141 VAL 141 141 141 VAL VAL C . n 
C 1 142 TYR 142 142 142 TYR TYR C . n 
C 1 143 ARG 143 143 143 ARG ARG C . n 
C 1 144 SER 144 144 144 SER SER C . n 
C 1 145 ALA 145 145 145 ALA ALA C . n 
C 1 146 ILE 146 146 146 ILE ILE C . n 
C 1 147 GLY 147 147 147 GLY GLY C . n 
C 1 148 VAL 148 148 148 VAL VAL C . n 
C 1 149 VAL 149 149 149 VAL VAL C . n 
C 1 150 GLY 150 150 150 GLY GLY C . n 
C 1 151 VAL 151 151 151 VAL VAL C . n 
C 1 152 ILE 152 152 152 ILE ILE C . n 
C 1 153 SER 153 153 153 SER SER C . n 
C 1 154 PRO 154 154 154 PRO PRO C . n 
C 1 155 TRP 155 155 155 TRP TRP C . n 
C 1 156 ASN 156 156 156 ASN ASN C . n 
C 1 157 PHE 157 157 157 PHE PHE C . n 
C 1 158 PRO 158 158 158 PRO PRO C . n 
C 1 159 LEU 159 159 159 LEU LEU C . n 
C 1 160 HIS 160 160 160 HIS HIS C . n 
C 1 161 LEU 161 161 161 LEU LEU C . n 
C 1 162 THR 162 162 162 THR THR C . n 
C 1 163 GLN 163 163 163 GLN GLN C . n 
C 1 164 ARG 164 164 164 ARG ARG C . n 
C 1 165 SER 165 165 165 SER SER C . n 
C 1 166 ILE 166 166 166 ILE ILE C . n 
C 1 167 ALA 167 167 167 ALA ALA C . n 
C 1 168 PRO 168 168 168 PRO PRO C . n 
C 1 169 ALA 169 169 169 ALA ALA C . n 
C 1 170 LEU 170 170 170 LEU LEU C . n 
C 1 171 ALA 171 171 171 ALA ALA C . n 
C 1 172 LEU 172 172 172 LEU LEU C . n 
C 1 173 GLY 173 173 173 GLY GLY C . n 
C 1 174 ASN 174 174 174 ASN ASN C . n 
C 1 175 ALA 175 175 175 ALA ALA C . n 
C 1 176 VAL 176 176 176 VAL VAL C . n 
C 1 177 VAL 177 177 177 VAL VAL C . n 
C 1 178 VAL 178 178 178 VAL VAL C . n 
C 1 179 LYS 179 179 179 LYS LYS C . n 
C 1 180 PRO 180 180 180 PRO PRO C . n 
C 1 181 ALA 181 181 181 ALA ALA C . n 
C 1 182 SER 182 182 182 SER SER C . n 
C 1 183 ASP 183 183 183 ASP ASP C . n 
C 1 184 THR 184 184 184 THR THR C . n 
C 1 185 PRO 185 185 185 PRO PRO C . n 
C 1 186 VAL 186 186 186 VAL VAL C . n 
C 1 187 CYS 187 187 187 CYS CYS C . n 
C 1 188 GLY 188 188 188 GLY GLY C . n 
C 1 189 GLY 189 189 189 GLY GLY C . n 
C 1 190 LEU 190 190 190 LEU LEU C . n 
C 1 191 LEU 191 191 191 LEU LEU C . n 
C 1 192 LEU 192 192 192 LEU LEU C . n 
C 1 193 ALA 193 193 193 ALA ALA C . n 
C 1 194 ARG 194 194 194 ARG ARG C . n 
C 1 195 ILE 195 195 195 ILE ILE C . n 
C 1 196 PHE 196 196 196 PHE PHE C . n 
C 1 197 GLU 197 197 197 GLU GLU C . n 
C 1 198 GLU 198 198 198 GLU GLU C . n 
C 1 199 ALA 199 199 199 ALA ALA C . n 
C 1 200 GLY 200 200 200 GLY GLY C . n 
C 1 201 LEU 201 201 201 LEU LEU C . n 
C 1 202 PRO 202 202 202 PRO PRO C . n 
C 1 203 ALA 203 203 203 ALA ALA C . n 
C 1 204 GLY 204 204 204 GLY GLY C . n 
C 1 205 LEU 205 205 205 LEU LEU C . n 
C 1 206 PHE 206 206 206 PHE PHE C . n 
C 1 207 SER 207 207 207 SER SER C . n 
C 1 208 VAL 208 208 208 VAL VAL C . n 
C 1 209 VAL 209 209 209 VAL VAL C . n 
C 1 210 VAL 210 210 210 VAL VAL C . n 
C 1 211 GLY 211 211 211 GLY GLY C . n 
C 1 212 PRO 212 212 212 PRO PRO C . n 
C 1 213 GLY 213 213 213 GLY GLY C . n 
C 1 214 SER 214 214 214 SER SER C . n 
C 1 215 GLU 215 215 215 GLU GLU C . n 
C 1 216 ILE 216 216 216 ILE ILE C . n 
C 1 217 GLY 217 217 217 GLY GLY C . n 
C 1 218 ASP 218 218 218 ASP ASP C . n 
C 1 219 ALA 219 219 219 ALA ALA C . n 
C 1 220 PHE 220 220 220 PHE PHE C . n 
C 1 221 VAL 221 221 221 VAL VAL C . n 
C 1 222 GLU 222 222 222 GLU GLU C . n 
C 1 223 HIS 223 223 223 HIS HIS C . n 
C 1 224 PRO 224 224 224 PRO PRO C . n 
C 1 225 VAL 225 225 225 VAL VAL C . n 
C 1 226 PRO 226 226 226 PRO PRO C . n 
C 1 227 GLY 227 227 227 GLY GLY C . n 
C 1 228 LEU 228 228 228 LEU LEU C . n 
C 1 229 VAL 229 229 229 VAL VAL C . n 
C 1 230 THR 230 230 230 THR THR C . n 
C 1 231 PHE 231 231 231 PHE PHE C . n 
C 1 232 THR 232 232 232 THR THR C . n 
C 1 233 GLY 233 233 233 GLY GLY C . n 
C 1 234 SER 234 234 234 SER SER C . n 
C 1 235 THR 235 235 235 THR THR C . n 
C 1 236 PRO 236 236 236 PRO PRO C . n 
C 1 237 VAL 237 237 237 VAL VAL C . n 
C 1 238 GLY 238 238 238 GLY GLY C . n 
C 1 239 ARG 239 239 239 ARG ARG C . n 
C 1 240 ASN 240 240 240 ASN ASN C . n 
C 1 241 ILE 241 241 241 ILE ILE C . n 
C 1 242 GLY 242 242 242 GLY GLY C . n 
C 1 243 ARG 243 243 243 ARG ARG C . n 
C 1 244 ILE 244 244 244 ILE ILE C . n 
C 1 245 ALA 245 245 245 ALA ALA C . n 
C 1 246 SER 246 246 246 SER SER C . n 
C 1 247 GLY 247 247 247 GLY GLY C . n 
C 1 248 GLY 248 248 248 GLY GLY C . n 
C 1 249 ALA 249 249 249 ALA ALA C . n 
C 1 250 HIS 250 250 250 HIS HIS C . n 
C 1 251 LEU 251 251 251 LEU LEU C . n 
C 1 252 LYS 252 252 252 LYS LYS C . n 
C 1 253 HIS 253 253 253 HIS HIS C . n 
C 1 254 VAL 254 254 254 VAL VAL C . n 
C 1 255 ALA 255 255 255 ALA ALA C . n 
C 1 256 LEU 256 256 256 LEU LEU C . n 
C 1 257 GLU 257 257 257 GLU GLU C . n 
C 1 258 LEU 258 258 258 LEU LEU C . n 
C 1 259 GLY 259 259 259 GLY GLY C . n 
C 1 260 GLY 260 260 260 GLY GLY C . n 
C 1 261 ASN 261 261 261 ASN ASN C . n 
C 1 262 SER 262 262 262 SER SER C . n 
C 1 263 PRO 263 263 263 PRO PRO C . n 
C 1 264 PHE 264 264 264 PHE PHE C . n 
C 1 265 VAL 265 265 265 VAL VAL C . n 
C 1 266 VAL 266 266 266 VAL VAL C . n 
C 1 267 LEU 267 267 267 LEU LEU C . n 
C 1 268 GLY 268 268 268 GLY GLY C . n 
C 1 269 ASP 269 269 269 ASP ASP C . n 
C 1 270 ALA 270 270 270 ALA ALA C . n 
C 1 271 ASP 271 271 271 ASP ASP C . n 
C 1 272 LEU 272 272 272 LEU LEU C . n 
C 1 273 GLU 273 273 273 GLU GLU C . n 
C 1 274 GLN 274 274 274 GLN GLN C . n 
C 1 275 ALA 275 275 275 ALA ALA C . n 
C 1 276 VAL 276 276 276 VAL VAL C . n 
C 1 277 SER 277 277 277 SER SER C . n 
C 1 278 ALA 278 278 278 ALA ALA C . n 
C 1 279 ALA 279 279 279 ALA ALA C . n 
C 1 280 VAL 280 280 280 VAL VAL C . n 
C 1 281 PHE 281 281 281 PHE PHE C . n 
C 1 282 GLY 282 282 282 GLY GLY C . n 
C 1 283 LYS 283 283 283 LYS LYS C . n 
C 1 284 PHE 284 284 284 PHE PHE C . n 
C 1 285 LEU 285 285 285 LEU LEU C . n 
C 1 286 HIS 286 286 286 HIS HIS C . n 
C 1 287 GLN 287 287 287 GLN GLN C . n 
C 1 288 GLY 288 288 288 GLY GLY C . n 
C 1 289 GLN 289 289 ?   ?   ?   C . n 
C 1 290 ILE 290 290 ?   ?   ?   C . n 
C 1 291 CYS 291 291 ?   ?   ?   C . n 
C 1 292 MET 292 292 ?   ?   ?   C . n 
C 1 293 ALA 293 293 ?   ?   ?   C . n 
C 1 294 ILE 294 294 294 ILE ILE C . n 
C 1 295 ASN 295 295 295 ASN ASN C . n 
C 1 296 ARG 296 296 296 ARG ARG C . n 
C 1 297 ILE 297 297 297 ILE ILE C . n 
C 1 298 ILE 298 298 298 ILE ILE C . n 
C 1 299 VAL 299 299 299 VAL VAL C . n 
C 1 300 GLU 300 300 300 GLU GLU C . n 
C 1 301 ASP 301 301 301 ASP ASP C . n 
C 1 302 SER 302 302 302 SER SER C . n 
C 1 303 LEU 303 303 303 LEU LEU C . n 
C 1 304 TYR 304 304 304 TYR TYR C . n 
C 1 305 ASP 305 305 305 ASP ASP C . n 
C 1 306 ALA 306 306 306 ALA ALA C . n 
C 1 307 PHE 307 307 307 PHE PHE C . n 
C 1 308 ALA 308 308 308 ALA ALA C . n 
C 1 309 ALA 309 309 309 ALA ALA C . n 
C 1 310 ARG 310 310 310 ARG ARG C . n 
C 1 311 PHE 311 311 311 PHE PHE C . n 
C 1 312 VAL 312 312 312 VAL VAL C . n 
C 1 313 GLU 313 313 313 GLU GLU C . n 
C 1 314 ARG 314 314 314 ARG ARG C . n 
C 1 315 VAL 315 315 315 VAL VAL C . n 
C 1 316 LYS 316 316 316 LYS LYS C . n 
C 1 317 GLY 317 317 317 GLY GLY C . n 
C 1 318 LEU 318 318 318 LEU LEU C . n 
C 1 319 ARG 319 319 319 ARG ARG C . n 
C 1 320 VAL 320 320 320 VAL VAL C . n 
C 1 321 GLY 321 321 321 GLY GLY C . n 
C 1 322 ASP 322 322 322 ASP ASP C . n 
C 1 323 PRO 323 323 323 PRO PRO C . n 
C 1 324 GLN 324 324 324 GLN GLN C . n 
C 1 325 ARG 325 325 325 ARG ARG C . n 
C 1 326 ALA 326 326 326 ALA ALA C . n 
C 1 327 ASP 327 327 327 ASP ASP C . n 
C 1 328 THR 328 328 328 THR THR C . n 
C 1 329 ALA 329 329 329 ALA ALA C . n 
C 1 330 VAL 330 330 330 VAL VAL C . n 
C 1 331 GLY 331 331 331 GLY GLY C . n 
C 1 332 PRO 332 332 332 PRO PRO C . n 
C 1 333 ILE 333 333 333 ILE ILE C . n 
C 1 334 VAL 334 334 334 VAL VAL C . n 
C 1 335 ASN 335 335 335 ASN ASN C . n 
C 1 336 ALA 336 336 336 ALA ALA C . n 
C 1 337 ARG 337 337 337 ARG ARG C . n 
C 1 338 GLN 338 338 338 GLN GLN C . n 
C 1 339 LEU 339 339 339 LEU LEU C . n 
C 1 340 GLU 340 340 340 GLU GLU C . n 
C 1 341 GLY 341 341 341 GLY GLY C . n 
C 1 342 LEU 342 342 342 LEU LEU C . n 
C 1 343 LEU 343 343 343 LEU LEU C . n 
C 1 344 GLU 344 344 344 GLU GLU C . n 
C 1 345 LYS 345 345 345 LYS LYS C . n 
C 1 346 ILE 346 346 346 ILE ILE C . n 
C 1 347 ARG 347 347 347 ARG ARG C . n 
C 1 348 LEU 348 348 348 LEU LEU C . n 
C 1 349 ALA 349 349 349 ALA ALA C . n 
C 1 350 ARG 350 350 350 ARG ARG C . n 
C 1 351 GLN 351 351 351 GLN GLN C . n 
C 1 352 GLU 352 352 352 GLU GLU C . n 
C 1 353 GLY 353 353 353 GLY GLY C . n 
C 1 354 ALA 354 354 354 ALA ALA C . n 
C 1 355 LYS 355 355 355 LYS LYS C . n 
C 1 356 PRO 356 356 356 PRO PRO C . n 
C 1 357 LEU 357 357 357 LEU LEU C . n 
C 1 358 TYR 358 358 358 TYR TYR C . n 
C 1 359 GLU 359 359 359 GLU GLU C . n 
C 1 360 GLY 360 360 360 GLY GLY C . n 
C 1 361 GLY 361 361 361 GLY GLY C . n 
C 1 362 VAL 362 362 362 VAL VAL C . n 
C 1 363 ASP 363 363 363 ASP ASP C . n 
C 1 364 GLY 364 364 364 GLY GLY C . n 
C 1 365 GLN 365 365 365 GLN GLN C . n 
C 1 366 LEU 366 366 366 LEU LEU C . n 
C 1 367 LEU 367 367 367 LEU LEU C . n 
C 1 368 ALA 368 368 368 ALA ALA C . n 
C 1 369 PRO 369 369 369 PRO PRO C . n 
C 1 370 HIS 370 370 370 HIS HIS C . n 
C 1 371 VAL 371 371 371 VAL VAL C . n 
C 1 372 PHE 372 372 372 PHE PHE C . n 
C 1 373 GLY 373 373 373 GLY GLY C . n 
C 1 374 GLU 374 374 374 GLU GLU C . n 
C 1 375 VAL 375 375 375 VAL VAL C . n 
C 1 376 THR 376 376 376 THR THR C . n 
C 1 377 ALA 377 377 377 ALA ALA C . n 
C 1 378 THR 378 378 378 THR THR C . n 
C 1 379 MET 379 379 379 MET MET C . n 
C 1 380 GLU 380 380 380 GLU GLU C . n 
C 1 381 ILE 381 381 381 ILE ILE C . n 
C 1 382 ALA 382 382 382 ALA ALA C . n 
C 1 383 ARG 383 383 383 ARG ARG C . n 
C 1 384 ASP 384 384 384 ASP ASP C . n 
C 1 385 GLU 385 385 385 GLU GLU C . n 
C 1 386 ILE 386 386 386 ILE ILE C . n 
C 1 387 PHE 387 387 387 PHE PHE C . n 
C 1 388 GLY 388 388 388 GLY GLY C . n 
C 1 389 PRO 389 389 389 PRO PRO C . n 
C 1 390 LEU 390 390 390 LEU LEU C . n 
C 1 391 VAL 391 391 391 VAL VAL C . n 
C 1 392 GLY 392 392 392 GLY GLY C . n 
C 1 393 LEU 393 393 393 LEU LEU C . n 
C 1 394 LEU 394 394 394 LEU LEU C . n 
C 1 395 ARG 395 395 395 ARG ARG C . n 
C 1 396 ALA 396 396 396 ALA ALA C . n 
C 1 397 ARG 397 397 397 ARG ARG C . n 
C 1 398 ASP 398 398 398 ASP ASP C . n 
C 1 399 GLU 399 399 399 GLU GLU C . n 
C 1 400 ALA 400 400 400 ALA ALA C . n 
C 1 401 HIS 401 401 401 HIS HIS C . n 
C 1 402 ALA 402 402 402 ALA ALA C . n 
C 1 403 LEU 403 403 403 LEU LEU C . n 
C 1 404 GLU 404 404 404 GLU GLU C . n 
C 1 405 LEU 405 405 405 LEU LEU C . n 
C 1 406 ALA 406 406 406 ALA ALA C . n 
C 1 407 ASN 407 407 407 ASN ASN C . n 
C 1 408 ALA 408 408 408 ALA ALA C . n 
C 1 409 SER 409 409 409 SER SER C . n 
C 1 410 GLU 410 410 410 GLU GLU C . n 
C 1 411 TYR 411 411 411 TYR TYR C . n 
C 1 412 GLY 412 412 412 GLY GLY C . n 
C 1 413 LEU 413 413 413 LEU LEU C . n 
C 1 414 SER 414 414 414 SER SER C . n 
C 1 415 SER 415 415 415 SER SER C . n 
C 1 416 ALA 416 416 416 ALA ALA C . n 
C 1 417 VAL 417 417 417 VAL VAL C . n 
C 1 418 PHE 418 418 418 PHE PHE C . n 
C 1 419 SER 419 419 419 SER SER C . n 
C 1 420 ARG 420 420 420 ARG ARG C . n 
C 1 421 ASP 421 421 421 ASP ASP C . n 
C 1 422 LEU 422 422 422 LEU LEU C . n 
C 1 423 GLU 423 423 423 GLU GLU C . n 
C 1 424 ARG 424 424 424 ARG ARG C . n 
C 1 425 ALA 425 425 425 ALA ALA C . n 
C 1 426 VAL 426 426 426 VAL VAL C . n 
C 1 427 ARG 427 427 427 ARG ARG C . n 
C 1 428 PHE 428 428 428 PHE PHE C . n 
C 1 429 ALA 429 429 429 ALA ALA C . n 
C 1 430 ARG 430 430 430 ARG ARG C . n 
C 1 431 GLN 431 431 431 GLN GLN C . n 
C 1 432 LEU 432 432 432 LEU LEU C . n 
C 1 433 ARG 433 433 433 ARG ARG C . n 
C 1 434 ALA 434 434 434 ALA ALA C . n 
C 1 435 GLY 435 435 435 GLY GLY C . n 
C 1 436 MET 436 436 436 MET MET C . n 
C 1 437 THR 437 437 437 THR THR C . n 
C 1 438 HIS 438 438 438 HIS HIS C . n 
C 1 439 VAL 439 439 439 VAL VAL C . n 
C 1 440 ASN 440 440 440 ASN ASN C . n 
C 1 441 ASP 441 441 441 ASP ASP C . n 
C 1 442 ILE 442 442 442 ILE ILE C . n 
C 1 443 PRO 443 443 443 PRO PRO C . n 
C 1 444 VAL 444 444 444 VAL VAL C . n 
C 1 445 ASN 445 445 445 ASN ASN C . n 
C 1 446 ASP 446 446 446 ASP ASP C . n 
C 1 447 GLU 447 447 ?   ?   ?   C . n 
C 1 448 ALA 448 448 ?   ?   ?   C . n 
C 1 449 ASN 449 449 ?   ?   ?   C . n 
C 1 450 ALA 450 450 ?   ?   ?   C . n 
C 1 451 PRO 451 451 ?   ?   ?   C . n 
C 1 452 PHE 452 452 ?   ?   ?   C . n 
C 1 453 GLY 453 453 ?   ?   ?   C . n 
C 1 454 GLY 454 454 ?   ?   ?   C . n 
C 1 455 GLU 455 455 ?   ?   ?   C . n 
C 1 456 LYS 456 456 ?   ?   ?   C . n 
C 1 457 ASN 457 457 ?   ?   ?   C . n 
C 1 458 SER 458 458 458 SER SER C . n 
C 1 459 GLY 459 459 459 GLY GLY C . n 
C 1 460 LEU 460 460 460 LEU LEU C . n 
C 1 461 GLY 461 461 461 GLY GLY C . n 
C 1 462 ARG 462 462 462 ARG ARG C . n 
C 1 463 PHE 463 463 463 PHE PHE C . n 
C 1 464 ASN 464 464 464 ASN ASN C . n 
C 1 465 GLY 465 465 465 GLY GLY C . n 
C 1 466 ASP 466 466 466 ASP ASP C . n 
C 1 467 TRP 467 467 467 TRP TRP C . n 
C 1 468 ALA 468 468 468 ALA ALA C . n 
C 1 469 ILE 469 469 469 ILE ILE C . n 
C 1 470 GLU 470 470 470 GLU GLU C . n 
C 1 471 GLU 471 471 471 GLU GLU C . n 
C 1 472 PHE 472 472 472 PHE PHE C . n 
C 1 473 THR 473 473 473 THR THR C . n 
C 1 474 THR 474 474 474 THR THR C . n 
C 1 475 ASP 475 475 475 ASP ASP C . n 
C 1 476 HIS 476 476 476 HIS HIS C . n 
C 1 477 TRP 477 477 477 TRP TRP C . n 
C 1 478 ILE 478 478 478 ILE ILE C . n 
C 1 479 SER 479 479 479 SER SER C . n 
C 1 480 VAL 480 480 480 VAL VAL C . n 
C 1 481 GLN 481 481 481 GLN GLN C . n 
C 1 482 HIS 482 482 482 HIS HIS C . n 
C 1 483 ALA 483 483 ?   ?   ?   C . n 
C 1 484 PRO 484 484 ?   ?   ?   C . n 
C 1 485 ARG 485 485 ?   ?   ?   C . n 
C 1 486 GLN 486 486 ?   ?   ?   C . n 
C 1 487 TYR 487 487 ?   ?   ?   C . n 
C 1 488 PRO 488 488 ?   ?   ?   C . n 
C 1 489 PHE 489 489 ?   ?   ?   C . n 
D 1 1   MET 1   1   ?   ?   ?   D . n 
D 1 2   SER 2   2   ?   ?   ?   D . n 
D 1 3   ASP 3   3   3   ASP ASP D . n 
D 1 4   SER 4   4   4   SER SER D . n 
D 1 5   ARG 5   5   5   ARG ARG D . n 
D 1 6   TYR 6   6   6   TYR TYR D . n 
D 1 7   THR 7   7   7   THR THR D . n 
D 1 8   ASP 8   8   8   ASP ASP D . n 
D 1 9   LEU 9   9   9   LEU LEU D . n 
D 1 10  GLY 10  10  10  GLY GLY D . n 
D 1 11  LEU 11  11  11  LEU LEU D . n 
D 1 12  GLN 12  12  12  GLN GLN D . n 
D 1 13  PRO 13  13  13  PRO PRO D . n 
D 1 14  LEU 14  14  14  LEU LEU D . n 
D 1 15  ALA 15  15  15  ALA ALA D . n 
D 1 16  GLY 16  16  16  GLY GLY D . n 
D 1 17  GLU 17  17  17  GLU GLU D . n 
D 1 18  TRP 18  18  18  TRP TRP D . n 
D 1 19  ARG 19  19  19  ARG ARG D . n 
D 1 20  HIS 20  20  20  HIS HIS D . n 
D 1 21  GLY 21  21  21  GLY GLY D . n 
D 1 22  ARG 22  22  22  ARG ARG D . n 
D 1 23  ALA 23  23  23  ALA ALA D . n 
D 1 24  GLY 24  24  24  GLY GLY D . n 
D 1 25  ARG 25  25  25  ARG ARG D . n 
D 1 26  ARG 26  26  26  ARG ARG D . n 
D 1 27  LEU 27  27  27  LEU LEU D . n 
D 1 28  LYS 28  28  28  LYS LYS D . n 
D 1 29  VAL 29  29  29  VAL VAL D . n 
D 1 30  SER 30  30  30  SER SER D . n 
D 1 31  ASN 31  31  31  ASN ASN D . n 
D 1 32  PRO 32  32  32  PRO PRO D . n 
D 1 33  PHE 33  33  33  PHE PHE D . n 
D 1 34  ASP 34  34  34  ASP ASP D . n 
D 1 35  GLY 35  35  35  GLY GLY D . n 
D 1 36  SER 36  36  36  SER SER D . n 
D 1 37  LEU 37  37  37  LEU LEU D . n 
D 1 38  LEU 38  38  38  LEU LEU D . n 
D 1 39  LEU 39  39  39  LEU LEU D . n 
D 1 40  GLU 40  40  40  GLU GLU D . n 
D 1 41  ILE 41  41  41  ILE ILE D . n 
D 1 42  GLU 42  42  42  GLU GLU D . n 
D 1 43  GLN 43  43  43  GLN GLN D . n 
D 1 44  ALA 44  44  44  ALA ALA D . n 
D 1 45  ASP 45  45  45  ASP ASP D . n 
D 1 46  ARG 46  46  46  ARG ARG D . n 
D 1 47  ASP 47  47  47  ASP ASP D . n 
D 1 48  ASP 48  48  48  ASP ASP D . n 
D 1 49  LEU 49  49  49  LEU LEU D . n 
D 1 50  ASP 50  50  50  ASP ASP D . n 
D 1 51  ALA 51  51  51  ALA ALA D . n 
D 1 52  ALA 52  52  52  ALA ALA D . n 
D 1 53  TYR 53  53  53  TYR TYR D . n 
D 1 54  ALA 54  54  54  ALA ALA D . n 
D 1 55  LYS 55  55  55  LYS LYS D . n 
D 1 56  ALA 56  56  56  ALA ALA D . n 
D 1 57  ALA 57  57  57  ALA ALA D . n 
D 1 58  GLU 58  58  58  GLU GLU D . n 
D 1 59  VAL 59  59  59  VAL VAL D . n 
D 1 60  GLN 60  60  60  GLN GLN D . n 
D 1 61  PRO 61  61  61  PRO PRO D . n 
D 1 62  ALA 62  62  62  ALA ALA D . n 
D 1 63  TRP 63  63  63  TRP TRP D . n 
D 1 64  ALA 64  64  64  ALA ALA D . n 
D 1 65  ALA 65  65  65  ALA ALA D . n 
D 1 66  LEU 66  66  66  LEU LEU D . n 
D 1 67  GLY 67  67  67  GLY GLY D . n 
D 1 68  PRO 68  68  68  PRO PRO D . n 
D 1 69  SER 69  69  69  SER SER D . n 
D 1 70  ALA 70  70  70  ALA ALA D . n 
D 1 71  ARG 71  71  71  ARG ARG D . n 
D 1 72  ALA 72  72  72  ALA ALA D . n 
D 1 73  ALA 73  73  73  ALA ALA D . n 
D 1 74  VAL 74  74  74  VAL VAL D . n 
D 1 75  LEU 75  75  75  LEU LEU D . n 
D 1 76  TYR 76  76  76  TYR TYR D . n 
D 1 77  LYS 77  77  77  LYS LYS D . n 
D 1 78  ALA 78  78  78  ALA ALA D . n 
D 1 79  VAL 79  79  79  VAL VAL D . n 
D 1 80  GLU 80  80  80  GLU GLU D . n 
D 1 81  VAL 81  81  81  VAL VAL D . n 
D 1 82  PHE 82  82  82  PHE PHE D . n 
D 1 83  ASP 83  83  83  ASP ASP D . n 
D 1 84  ARG 84  84  84  ARG ARG D . n 
D 1 85  ARG 85  85  85  ARG ARG D . n 
D 1 86  HIS 86  86  86  HIS HIS D . n 
D 1 87  GLU 87  87  87  GLU GLU D . n 
D 1 88  GLU 88  88  88  GLU GLU D . n 
D 1 89  ILE 89  89  89  ILE ILE D . n 
D 1 90  VAL 90  90  90  VAL VAL D . n 
D 1 91  ASP 91  91  91  ASP ASP D . n 
D 1 92  TRP 92  92  92  TRP TRP D . n 
D 1 93  ILE 93  93  93  ILE ILE D . n 
D 1 94  ILE 94  94  94  ILE ILE D . n 
D 1 95  ARG 95  95  95  ARG ARG D . n 
D 1 96  GLU 96  96  96  GLU GLU D . n 
D 1 97  SER 97  97  97  SER SER D . n 
D 1 98  GLY 98  98  98  GLY GLY D . n 
D 1 99  SER 99  99  99  SER SER D . n 
D 1 100 THR 100 100 100 THR THR D . n 
D 1 101 ARG 101 101 101 ARG ARG D . n 
D 1 102 LEU 102 102 102 LEU LEU D . n 
D 1 103 LYS 103 103 103 LYS LYS D . n 
D 1 104 ALA 104 104 104 ALA ALA D . n 
D 1 105 GLU 105 105 105 GLU GLU D . n 
D 1 106 ILE 106 106 106 ILE ILE D . n 
D 1 107 GLU 107 107 107 GLU GLU D . n 
D 1 108 TRP 108 108 108 TRP TRP D . n 
D 1 109 GLY 109 109 109 GLY GLY D . n 
D 1 110 ALA 110 110 110 ALA ALA D . n 
D 1 111 ALA 111 111 111 ALA ALA D . n 
D 1 112 ARG 112 112 112 ARG ARG D . n 
D 1 113 ALA 113 113 113 ALA ALA D . n 
D 1 114 ILE 114 114 114 ILE ILE D . n 
D 1 115 THR 115 115 115 THR THR D . n 
D 1 116 LEU 116 116 116 LEU LEU D . n 
D 1 117 GLU 117 117 117 GLU GLU D . n 
D 1 118 SER 118 118 118 SER SER D . n 
D 1 119 ALA 119 119 119 ALA ALA D . n 
D 1 120 SER 120 120 120 SER SER D . n 
D 1 121 PHE 121 121 121 PHE PHE D . n 
D 1 122 PRO 122 122 122 PRO PRO D . n 
D 1 123 ALA 123 123 123 ALA ALA D . n 
D 1 124 ARG 124 124 124 ARG ARG D . n 
D 1 125 VAL 125 125 125 VAL VAL D . n 
D 1 126 HIS 126 126 126 HIS HIS D . n 
D 1 127 GLY 127 127 127 GLY GLY D . n 
D 1 128 ARG 128 128 128 ARG ARG D . n 
D 1 129 ILE 129 129 129 ILE ILE D . n 
D 1 130 VAL 130 130 130 VAL VAL D . n 
D 1 131 GLU 131 131 131 GLU GLU D . n 
D 1 132 SER 132 132 132 SER SER D . n 
D 1 133 ASP 133 133 133 ASP ASP D . n 
D 1 134 VAL 134 134 134 VAL VAL D . n 
D 1 135 PRO 135 135 135 PRO PRO D . n 
D 1 136 GLY 136 136 136 GLY GLY D . n 
D 1 137 LYS 137 137 137 LYS LYS D . n 
D 1 138 GLU 138 138 138 GLU GLU D . n 
D 1 139 SER 139 139 139 SER SER D . n 
D 1 140 ARG 140 140 140 ARG ARG D . n 
D 1 141 VAL 141 141 141 VAL VAL D . n 
D 1 142 TYR 142 142 142 TYR TYR D . n 
D 1 143 ARG 143 143 143 ARG ARG D . n 
D 1 144 SER 144 144 144 SER SER D . n 
D 1 145 ALA 145 145 145 ALA ALA D . n 
D 1 146 ILE 146 146 146 ILE ILE D . n 
D 1 147 GLY 147 147 147 GLY GLY D . n 
D 1 148 VAL 148 148 148 VAL VAL D . n 
D 1 149 VAL 149 149 149 VAL VAL D . n 
D 1 150 GLY 150 150 150 GLY GLY D . n 
D 1 151 VAL 151 151 151 VAL VAL D . n 
D 1 152 ILE 152 152 152 ILE ILE D . n 
D 1 153 SER 153 153 153 SER SER D . n 
D 1 154 PRO 154 154 154 PRO PRO D . n 
D 1 155 TRP 155 155 155 TRP TRP D . n 
D 1 156 ASN 156 156 156 ASN ASN D . n 
D 1 157 PHE 157 157 157 PHE PHE D . n 
D 1 158 PRO 158 158 158 PRO PRO D . n 
D 1 159 LEU 159 159 159 LEU LEU D . n 
D 1 160 HIS 160 160 160 HIS HIS D . n 
D 1 161 LEU 161 161 161 LEU LEU D . n 
D 1 162 THR 162 162 162 THR THR D . n 
D 1 163 GLN 163 163 163 GLN GLN D . n 
D 1 164 ARG 164 164 164 ARG ARG D . n 
D 1 165 SER 165 165 165 SER SER D . n 
D 1 166 ILE 166 166 166 ILE ILE D . n 
D 1 167 ALA 167 167 167 ALA ALA D . n 
D 1 168 PRO 168 168 168 PRO PRO D . n 
D 1 169 ALA 169 169 169 ALA ALA D . n 
D 1 170 LEU 170 170 170 LEU LEU D . n 
D 1 171 ALA 171 171 171 ALA ALA D . n 
D 1 172 LEU 172 172 172 LEU LEU D . n 
D 1 173 GLY 173 173 173 GLY GLY D . n 
D 1 174 ASN 174 174 174 ASN ASN D . n 
D 1 175 ALA 175 175 175 ALA ALA D . n 
D 1 176 VAL 176 176 176 VAL VAL D . n 
D 1 177 VAL 177 177 177 VAL VAL D . n 
D 1 178 VAL 178 178 178 VAL VAL D . n 
D 1 179 LYS 179 179 179 LYS LYS D . n 
D 1 180 PRO 180 180 180 PRO PRO D . n 
D 1 181 ALA 181 181 181 ALA ALA D . n 
D 1 182 SER 182 182 182 SER SER D . n 
D 1 183 ASP 183 183 183 ASP ASP D . n 
D 1 184 THR 184 184 184 THR THR D . n 
D 1 185 PRO 185 185 185 PRO PRO D . n 
D 1 186 VAL 186 186 186 VAL VAL D . n 
D 1 187 CYS 187 187 187 CYS CYS D . n 
D 1 188 GLY 188 188 188 GLY GLY D . n 
D 1 189 GLY 189 189 189 GLY GLY D . n 
D 1 190 LEU 190 190 190 LEU LEU D . n 
D 1 191 LEU 191 191 191 LEU LEU D . n 
D 1 192 LEU 192 192 192 LEU LEU D . n 
D 1 193 ALA 193 193 193 ALA ALA D . n 
D 1 194 ARG 194 194 194 ARG ARG D . n 
D 1 195 ILE 195 195 195 ILE ILE D . n 
D 1 196 PHE 196 196 196 PHE PHE D . n 
D 1 197 GLU 197 197 197 GLU GLU D . n 
D 1 198 GLU 198 198 198 GLU GLU D . n 
D 1 199 ALA 199 199 199 ALA ALA D . n 
D 1 200 GLY 200 200 200 GLY GLY D . n 
D 1 201 LEU 201 201 201 LEU LEU D . n 
D 1 202 PRO 202 202 202 PRO PRO D . n 
D 1 203 ALA 203 203 203 ALA ALA D . n 
D 1 204 GLY 204 204 204 GLY GLY D . n 
D 1 205 LEU 205 205 205 LEU LEU D . n 
D 1 206 PHE 206 206 206 PHE PHE D . n 
D 1 207 SER 207 207 207 SER SER D . n 
D 1 208 VAL 208 208 208 VAL VAL D . n 
D 1 209 VAL 209 209 209 VAL VAL D . n 
D 1 210 VAL 210 210 210 VAL VAL D . n 
D 1 211 GLY 211 211 211 GLY GLY D . n 
D 1 212 PRO 212 212 212 PRO PRO D . n 
D 1 213 GLY 213 213 213 GLY GLY D . n 
D 1 214 SER 214 214 214 SER SER D . n 
D 1 215 GLU 215 215 215 GLU GLU D . n 
D 1 216 ILE 216 216 216 ILE ILE D . n 
D 1 217 GLY 217 217 217 GLY GLY D . n 
D 1 218 ASP 218 218 218 ASP ASP D . n 
D 1 219 ALA 219 219 219 ALA ALA D . n 
D 1 220 PHE 220 220 220 PHE PHE D . n 
D 1 221 VAL 221 221 221 VAL VAL D . n 
D 1 222 GLU 222 222 222 GLU GLU D . n 
D 1 223 HIS 223 223 223 HIS HIS D . n 
D 1 224 PRO 224 224 224 PRO PRO D . n 
D 1 225 VAL 225 225 225 VAL VAL D . n 
D 1 226 PRO 226 226 226 PRO PRO D . n 
D 1 227 GLY 227 227 227 GLY GLY D . n 
D 1 228 LEU 228 228 228 LEU LEU D . n 
D 1 229 VAL 229 229 229 VAL VAL D . n 
D 1 230 THR 230 230 230 THR THR D . n 
D 1 231 PHE 231 231 231 PHE PHE D . n 
D 1 232 THR 232 232 232 THR THR D . n 
D 1 233 GLY 233 233 233 GLY GLY D . n 
D 1 234 SER 234 234 234 SER SER D . n 
D 1 235 THR 235 235 235 THR THR D . n 
D 1 236 PRO 236 236 236 PRO PRO D . n 
D 1 237 VAL 237 237 237 VAL VAL D . n 
D 1 238 GLY 238 238 238 GLY GLY D . n 
D 1 239 ARG 239 239 239 ARG ARG D . n 
D 1 240 ASN 240 240 240 ASN ASN D . n 
D 1 241 ILE 241 241 241 ILE ILE D . n 
D 1 242 GLY 242 242 242 GLY GLY D . n 
D 1 243 ARG 243 243 243 ARG ARG D . n 
D 1 244 ILE 244 244 244 ILE ILE D . n 
D 1 245 ALA 245 245 245 ALA ALA D . n 
D 1 246 SER 246 246 246 SER SER D . n 
D 1 247 GLY 247 247 247 GLY GLY D . n 
D 1 248 GLY 248 248 248 GLY GLY D . n 
D 1 249 ALA 249 249 249 ALA ALA D . n 
D 1 250 HIS 250 250 250 HIS HIS D . n 
D 1 251 LEU 251 251 251 LEU LEU D . n 
D 1 252 LYS 252 252 252 LYS LYS D . n 
D 1 253 HIS 253 253 253 HIS HIS D . n 
D 1 254 VAL 254 254 254 VAL VAL D . n 
D 1 255 ALA 255 255 255 ALA ALA D . n 
D 1 256 LEU 256 256 256 LEU LEU D . n 
D 1 257 GLU 257 257 257 GLU GLU D . n 
D 1 258 LEU 258 258 258 LEU LEU D . n 
D 1 259 GLY 259 259 259 GLY GLY D . n 
D 1 260 GLY 260 260 260 GLY GLY D . n 
D 1 261 ASN 261 261 261 ASN ASN D . n 
D 1 262 SER 262 262 262 SER SER D . n 
D 1 263 PRO 263 263 263 PRO PRO D . n 
D 1 264 PHE 264 264 264 PHE PHE D . n 
D 1 265 VAL 265 265 265 VAL VAL D . n 
D 1 266 VAL 266 266 266 VAL VAL D . n 
D 1 267 LEU 267 267 267 LEU LEU D . n 
D 1 268 GLY 268 268 268 GLY GLY D . n 
D 1 269 ASP 269 269 269 ASP ASP D . n 
D 1 270 ALA 270 270 270 ALA ALA D . n 
D 1 271 ASP 271 271 271 ASP ASP D . n 
D 1 272 LEU 272 272 272 LEU LEU D . n 
D 1 273 GLU 273 273 273 GLU GLU D . n 
D 1 274 GLN 274 274 274 GLN GLN D . n 
D 1 275 ALA 275 275 275 ALA ALA D . n 
D 1 276 VAL 276 276 276 VAL VAL D . n 
D 1 277 SER 277 277 277 SER SER D . n 
D 1 278 ALA 278 278 278 ALA ALA D . n 
D 1 279 ALA 279 279 279 ALA ALA D . n 
D 1 280 VAL 280 280 280 VAL VAL D . n 
D 1 281 PHE 281 281 281 PHE PHE D . n 
D 1 282 GLY 282 282 282 GLY GLY D . n 
D 1 283 LYS 283 283 283 LYS LYS D . n 
D 1 284 PHE 284 284 284 PHE PHE D . n 
D 1 285 LEU 285 285 285 LEU LEU D . n 
D 1 286 HIS 286 286 286 HIS HIS D . n 
D 1 287 GLN 287 287 287 GLN GLN D . n 
D 1 288 GLY 288 288 ?   ?   ?   D . n 
D 1 289 GLN 289 289 ?   ?   ?   D . n 
D 1 290 ILE 290 290 ?   ?   ?   D . n 
D 1 291 CYS 291 291 ?   ?   ?   D . n 
D 1 292 MET 292 292 ?   ?   ?   D . n 
D 1 293 ALA 293 293 293 ALA ALA D . n 
D 1 294 ILE 294 294 294 ILE ILE D . n 
D 1 295 ASN 295 295 295 ASN ASN D . n 
D 1 296 ARG 296 296 296 ARG ARG D . n 
D 1 297 ILE 297 297 297 ILE ILE D . n 
D 1 298 ILE 298 298 298 ILE ILE D . n 
D 1 299 VAL 299 299 299 VAL VAL D . n 
D 1 300 GLU 300 300 300 GLU GLU D . n 
D 1 301 ASP 301 301 301 ASP ASP D . n 
D 1 302 SER 302 302 302 SER SER D . n 
D 1 303 LEU 303 303 303 LEU LEU D . n 
D 1 304 TYR 304 304 304 TYR TYR D . n 
D 1 305 ASP 305 305 305 ASP ASP D . n 
D 1 306 ALA 306 306 306 ALA ALA D . n 
D 1 307 PHE 307 307 307 PHE PHE D . n 
D 1 308 ALA 308 308 308 ALA ALA D . n 
D 1 309 ALA 309 309 309 ALA ALA D . n 
D 1 310 ARG 310 310 310 ARG ARG D . n 
D 1 311 PHE 311 311 311 PHE PHE D . n 
D 1 312 VAL 312 312 312 VAL VAL D . n 
D 1 313 GLU 313 313 313 GLU GLU D . n 
D 1 314 ARG 314 314 314 ARG ARG D . n 
D 1 315 VAL 315 315 315 VAL VAL D . n 
D 1 316 LYS 316 316 316 LYS LYS D . n 
D 1 317 GLY 317 317 317 GLY GLY D . n 
D 1 318 LEU 318 318 318 LEU LEU D . n 
D 1 319 ARG 319 319 319 ARG ARG D . n 
D 1 320 VAL 320 320 320 VAL VAL D . n 
D 1 321 GLY 321 321 321 GLY GLY D . n 
D 1 322 ASP 322 322 322 ASP ASP D . n 
D 1 323 PRO 323 323 323 PRO PRO D . n 
D 1 324 GLN 324 324 324 GLN GLN D . n 
D 1 325 ARG 325 325 325 ARG ARG D . n 
D 1 326 ALA 326 326 326 ALA ALA D . n 
D 1 327 ASP 327 327 327 ASP ASP D . n 
D 1 328 THR 328 328 328 THR THR D . n 
D 1 329 ALA 329 329 329 ALA ALA D . n 
D 1 330 VAL 330 330 330 VAL VAL D . n 
D 1 331 GLY 331 331 331 GLY GLY D . n 
D 1 332 PRO 332 332 332 PRO PRO D . n 
D 1 333 ILE 333 333 333 ILE ILE D . n 
D 1 334 VAL 334 334 334 VAL VAL D . n 
D 1 335 ASN 335 335 335 ASN ASN D . n 
D 1 336 ALA 336 336 336 ALA ALA D . n 
D 1 337 ARG 337 337 337 ARG ARG D . n 
D 1 338 GLN 338 338 338 GLN GLN D . n 
D 1 339 LEU 339 339 339 LEU LEU D . n 
D 1 340 GLU 340 340 340 GLU GLU D . n 
D 1 341 GLY 341 341 341 GLY GLY D . n 
D 1 342 LEU 342 342 342 LEU LEU D . n 
D 1 343 LEU 343 343 343 LEU LEU D . n 
D 1 344 GLU 344 344 344 GLU GLU D . n 
D 1 345 LYS 345 345 345 LYS LYS D . n 
D 1 346 ILE 346 346 346 ILE ILE D . n 
D 1 347 ARG 347 347 347 ARG ARG D . n 
D 1 348 LEU 348 348 348 LEU LEU D . n 
D 1 349 ALA 349 349 349 ALA ALA D . n 
D 1 350 ARG 350 350 350 ARG ARG D . n 
D 1 351 GLN 351 351 351 GLN GLN D . n 
D 1 352 GLU 352 352 352 GLU GLU D . n 
D 1 353 GLY 353 353 353 GLY GLY D . n 
D 1 354 ALA 354 354 354 ALA ALA D . n 
D 1 355 LYS 355 355 355 LYS LYS D . n 
D 1 356 PRO 356 356 356 PRO PRO D . n 
D 1 357 LEU 357 357 357 LEU LEU D . n 
D 1 358 TYR 358 358 358 TYR TYR D . n 
D 1 359 GLU 359 359 359 GLU GLU D . n 
D 1 360 GLY 360 360 360 GLY GLY D . n 
D 1 361 GLY 361 361 361 GLY GLY D . n 
D 1 362 VAL 362 362 362 VAL VAL D . n 
D 1 363 ASP 363 363 363 ASP ASP D . n 
D 1 364 GLY 364 364 364 GLY GLY D . n 
D 1 365 GLN 365 365 365 GLN GLN D . n 
D 1 366 LEU 366 366 366 LEU LEU D . n 
D 1 367 LEU 367 367 367 LEU LEU D . n 
D 1 368 ALA 368 368 368 ALA ALA D . n 
D 1 369 PRO 369 369 369 PRO PRO D . n 
D 1 370 HIS 370 370 370 HIS HIS D . n 
D 1 371 VAL 371 371 371 VAL VAL D . n 
D 1 372 PHE 372 372 372 PHE PHE D . n 
D 1 373 GLY 373 373 373 GLY GLY D . n 
D 1 374 GLU 374 374 374 GLU GLU D . n 
D 1 375 VAL 375 375 375 VAL VAL D . n 
D 1 376 THR 376 376 376 THR THR D . n 
D 1 377 ALA 377 377 377 ALA ALA D . n 
D 1 378 THR 378 378 378 THR THR D . n 
D 1 379 MET 379 379 379 MET MET D . n 
D 1 380 GLU 380 380 380 GLU GLU D . n 
D 1 381 ILE 381 381 381 ILE ILE D . n 
D 1 382 ALA 382 382 382 ALA ALA D . n 
D 1 383 ARG 383 383 383 ARG ARG D . n 
D 1 384 ASP 384 384 384 ASP ASP D . n 
D 1 385 GLU 385 385 385 GLU GLU D . n 
D 1 386 ILE 386 386 386 ILE ILE D . n 
D 1 387 PHE 387 387 387 PHE PHE D . n 
D 1 388 GLY 388 388 388 GLY GLY D . n 
D 1 389 PRO 389 389 389 PRO PRO D . n 
D 1 390 LEU 390 390 390 LEU LEU D . n 
D 1 391 VAL 391 391 391 VAL VAL D . n 
D 1 392 GLY 392 392 392 GLY GLY D . n 
D 1 393 LEU 393 393 393 LEU LEU D . n 
D 1 394 LEU 394 394 394 LEU LEU D . n 
D 1 395 ARG 395 395 395 ARG ARG D . n 
D 1 396 ALA 396 396 396 ALA ALA D . n 
D 1 397 ARG 397 397 397 ARG ARG D . n 
D 1 398 ASP 398 398 398 ASP ASP D . n 
D 1 399 GLU 399 399 399 GLU GLU D . n 
D 1 400 ALA 400 400 400 ALA ALA D . n 
D 1 401 HIS 401 401 401 HIS HIS D . n 
D 1 402 ALA 402 402 402 ALA ALA D . n 
D 1 403 LEU 403 403 403 LEU LEU D . n 
D 1 404 GLU 404 404 404 GLU GLU D . n 
D 1 405 LEU 405 405 405 LEU LEU D . n 
D 1 406 ALA 406 406 406 ALA ALA D . n 
D 1 407 ASN 407 407 407 ASN ASN D . n 
D 1 408 ALA 408 408 408 ALA ALA D . n 
D 1 409 SER 409 409 409 SER SER D . n 
D 1 410 GLU 410 410 410 GLU GLU D . n 
D 1 411 TYR 411 411 411 TYR TYR D . n 
D 1 412 GLY 412 412 412 GLY GLY D . n 
D 1 413 LEU 413 413 413 LEU LEU D . n 
D 1 414 SER 414 414 414 SER SER D . n 
D 1 415 SER 415 415 415 SER SER D . n 
D 1 416 ALA 416 416 416 ALA ALA D . n 
D 1 417 VAL 417 417 417 VAL VAL D . n 
D 1 418 PHE 418 418 418 PHE PHE D . n 
D 1 419 SER 419 419 419 SER SER D . n 
D 1 420 ARG 420 420 420 ARG ARG D . n 
D 1 421 ASP 421 421 421 ASP ASP D . n 
D 1 422 LEU 422 422 422 LEU LEU D . n 
D 1 423 GLU 423 423 423 GLU GLU D . n 
D 1 424 ARG 424 424 424 ARG ARG D . n 
D 1 425 ALA 425 425 425 ALA ALA D . n 
D 1 426 VAL 426 426 426 VAL VAL D . n 
D 1 427 ARG 427 427 427 ARG ARG D . n 
D 1 428 PHE 428 428 428 PHE PHE D . n 
D 1 429 ALA 429 429 429 ALA ALA D . n 
D 1 430 ARG 430 430 430 ARG ARG D . n 
D 1 431 GLN 431 431 431 GLN GLN D . n 
D 1 432 LEU 432 432 432 LEU LEU D . n 
D 1 433 ARG 433 433 433 ARG ARG D . n 
D 1 434 ALA 434 434 434 ALA ALA D . n 
D 1 435 GLY 435 435 435 GLY GLY D . n 
D 1 436 MET 436 436 436 MET MET D . n 
D 1 437 THR 437 437 437 THR THR D . n 
D 1 438 HIS 438 438 438 HIS HIS D . n 
D 1 439 VAL 439 439 439 VAL VAL D . n 
D 1 440 ASN 440 440 440 ASN ASN D . n 
D 1 441 ASP 441 441 441 ASP ASP D . n 
D 1 442 ILE 442 442 442 ILE ILE D . n 
D 1 443 PRO 443 443 443 PRO PRO D . n 
D 1 444 VAL 444 444 ?   ?   ?   D . n 
D 1 445 ASN 445 445 ?   ?   ?   D . n 
D 1 446 ASP 446 446 ?   ?   ?   D . n 
D 1 447 GLU 447 447 ?   ?   ?   D . n 
D 1 448 ALA 448 448 ?   ?   ?   D . n 
D 1 449 ASN 449 449 ?   ?   ?   D . n 
D 1 450 ALA 450 450 ?   ?   ?   D . n 
D 1 451 PRO 451 451 ?   ?   ?   D . n 
D 1 452 PHE 452 452 ?   ?   ?   D . n 
D 1 453 GLY 453 453 ?   ?   ?   D . n 
D 1 454 GLY 454 454 ?   ?   ?   D . n 
D 1 455 GLU 455 455 ?   ?   ?   D . n 
D 1 456 LYS 456 456 ?   ?   ?   D . n 
D 1 457 ASN 457 457 ?   ?   ?   D . n 
D 1 458 SER 458 458 ?   ?   ?   D . n 
D 1 459 GLY 459 459 459 GLY GLY D . n 
D 1 460 LEU 460 460 460 LEU LEU D . n 
D 1 461 GLY 461 461 461 GLY GLY D . n 
D 1 462 ARG 462 462 462 ARG ARG D . n 
D 1 463 PHE 463 463 463 PHE PHE D . n 
D 1 464 ASN 464 464 464 ASN ASN D . n 
D 1 465 GLY 465 465 465 GLY GLY D . n 
D 1 466 ASP 466 466 466 ASP ASP D . n 
D 1 467 TRP 467 467 467 TRP TRP D . n 
D 1 468 ALA 468 468 468 ALA ALA D . n 
D 1 469 ILE 469 469 469 ILE ILE D . n 
D 1 470 GLU 470 470 470 GLU GLU D . n 
D 1 471 GLU 471 471 471 GLU GLU D . n 
D 1 472 PHE 472 472 472 PHE PHE D . n 
D 1 473 THR 473 473 473 THR THR D . n 
D 1 474 THR 474 474 474 THR THR D . n 
D 1 475 ASP 475 475 475 ASP ASP D . n 
D 1 476 HIS 476 476 476 HIS HIS D . n 
D 1 477 TRP 477 477 477 TRP TRP D . n 
D 1 478 ILE 478 478 478 ILE ILE D . n 
D 1 479 SER 479 479 479 SER SER D . n 
D 1 480 VAL 480 480 480 VAL VAL D . n 
D 1 481 GLN 481 481 481 GLN GLN D . n 
D 1 482 HIS 482 482 482 HIS HIS D . n 
D 1 483 ALA 483 483 ?   ?   ?   D . n 
D 1 484 PRO 484 484 ?   ?   ?   D . n 
D 1 485 ARG 485 485 ?   ?   ?   D . n 
D 1 486 GLN 486 486 ?   ?   ?   D . n 
D 1 487 TYR 487 487 ?   ?   ?   D . n 
D 1 488 PRO 488 488 ?   ?   ?   D . n 
D 1 489 PHE 489 489 ?   ?   ?   D . n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
E 2 HOH 1  501 1277 HOH HOH A . 
E 2 HOH 2  502 1254 HOH HOH A . 
E 2 HOH 3  503 642  HOH HOH A . 
E 2 HOH 4  504 2265 HOH HOH A . 
E 2 HOH 5  505 2393 HOH HOH A . 
E 2 HOH 6  506 2442 HOH HOH A . 
E 2 HOH 7  507 592  HOH HOH A . 
E 2 HOH 8  508 1710 HOH HOH A . 
E 2 HOH 9  509 2612 HOH HOH A . 
E 2 HOH 10 510 2341 HOH HOH A . 
E 2 HOH 11 511 2391 HOH HOH A . 
E 2 HOH 12 512 2780 HOH HOH A . 
F 2 HOH 1  501 1155 HOH HOH B . 
F 2 HOH 2  502 1937 HOH HOH B . 
F 2 HOH 3  503 2658 HOH HOH B . 
F 2 HOH 4  504 2335 HOH HOH B . 
F 2 HOH 5  505 65   HOH HOH B . 
F 2 HOH 6  506 585  HOH HOH B . 
F 2 HOH 7  507 112  HOH HOH B . 
F 2 HOH 8  508 2208 HOH HOH B . 
F 2 HOH 9  509 2528 HOH HOH B . 
F 2 HOH 10 510 1652 HOH HOH B . 
F 2 HOH 11 511 621  HOH HOH B . 
F 2 HOH 12 512 1622 HOH HOH B . 
F 2 HOH 13 513 1684 HOH HOH B . 
F 2 HOH 14 514 166  HOH HOH B . 
F 2 HOH 15 515 1390 HOH HOH B . 
F 2 HOH 16 516 4    HOH HOH B . 
F 2 HOH 17 517 2    HOH HOH B . 
F 2 HOH 18 518 2516 HOH HOH B . 
F 2 HOH 19 519 590  HOH HOH B . 
F 2 HOH 20 520 173  HOH HOH B . 
F 2 HOH 21 521 1859 HOH HOH B . 
F 2 HOH 22 522 1819 HOH HOH B . 
F 2 HOH 23 523 2565 HOH HOH B . 
F 2 HOH 24 524 2743 HOH HOH B . 
F 2 HOH 25 525 616  HOH HOH B . 
F 2 HOH 26 526 2754 HOH HOH B . 
F 2 HOH 27 527 852  HOH HOH B . 
F 2 HOH 28 528 453  HOH HOH B . 
F 2 HOH 29 529 2247 HOH HOH B . 
F 2 HOH 30 530 1224 HOH HOH B . 
F 2 HOH 31 531 1183 HOH HOH B . 
F 2 HOH 32 532 2284 HOH HOH B . 
F 2 HOH 33 533 2615 HOH HOH B . 
F 2 HOH 34 534 2594 HOH HOH B . 
F 2 HOH 35 535 681  HOH HOH B . 
F 2 HOH 36 536 46   HOH HOH B . 
F 2 HOH 37 537 988  HOH HOH B . 
F 2 HOH 38 538 2782 HOH HOH B . 
F 2 HOH 39 539 1702 HOH HOH B . 
F 2 HOH 40 540 2437 HOH HOH B . 
F 2 HOH 41 541 1712 HOH HOH B . 
F 2 HOH 42 542 1638 HOH HOH B . 
F 2 HOH 43 543 1872 HOH HOH B . 
F 2 HOH 44 544 2358 HOH HOH B . 
G 2 HOH 1  501 1639 HOH HOH C . 
G 2 HOH 2  502 2538 HOH HOH C . 
G 2 HOH 3  503 1932 HOH HOH C . 
G 2 HOH 4  504 1069 HOH HOH C . 
G 2 HOH 5  505 1656 HOH HOH C . 
G 2 HOH 6  506 1137 HOH HOH C . 
G 2 HOH 7  507 2273 HOH HOH C . 
G 2 HOH 8  508 784  HOH HOH C . 
G 2 HOH 9  509 2490 HOH HOH C . 
G 2 HOH 10 510 930  HOH HOH C . 
G 2 HOH 11 511 589  HOH HOH C . 
G 2 HOH 12 512 86   HOH HOH C . 
G 2 HOH 13 513 599  HOH HOH C . 
G 2 HOH 14 514 2313 HOH HOH C . 
G 2 HOH 15 515 1734 HOH HOH C . 
G 2 HOH 16 516 1644 HOH HOH C . 
G 2 HOH 17 517 1717 HOH HOH C . 
G 2 HOH 18 518 828  HOH HOH C . 
G 2 HOH 19 519 1805 HOH HOH C . 
G 2 HOH 20 520 631  HOH HOH C . 
G 2 HOH 21 521 279  HOH HOH C . 
G 2 HOH 22 522 596  HOH HOH C . 
G 2 HOH 23 523 1117 HOH HOH C . 
G 2 HOH 24 524 2573 HOH HOH C . 
G 2 HOH 25 525 2402 HOH HOH C . 
G 2 HOH 26 526 1934 HOH HOH C . 
G 2 HOH 27 527 1704 HOH HOH C . 
G 2 HOH 28 528 881  HOH HOH C . 
G 2 HOH 29 529 1675 HOH HOH C . 
G 2 HOH 30 530 627  HOH HOH C . 
G 2 HOH 31 531 154  HOH HOH C . 
G 2 HOH 32 532 1827 HOH HOH C . 
G 2 HOH 33 533 2515 HOH HOH C . 
G 2 HOH 34 534 2682 HOH HOH C . 
G 2 HOH 35 535 1705 HOH HOH C . 
G 2 HOH 36 536 15   HOH HOH C . 
G 2 HOH 37 537 1847 HOH HOH C . 
G 2 HOH 38 538 2268 HOH HOH C . 
G 2 HOH 39 539 1362 HOH HOH C . 
G 2 HOH 40 540 608  HOH HOH C . 
G 2 HOH 41 541 1815 HOH HOH C . 
G 2 HOH 42 542 1161 HOH HOH C . 
G 2 HOH 43 543 2449 HOH HOH C . 
G 2 HOH 44 544 2431 HOH HOH C . 
G 2 HOH 45 545 1626 HOH HOH C . 
G 2 HOH 46 546 1913 HOH HOH C . 
G 2 HOH 47 547 2625 HOH HOH C . 
G 2 HOH 48 548 2193 HOH HOH C . 
G 2 HOH 49 549 1714 HOH HOH C . 
G 2 HOH 50 550 2805 HOH HOH C . 
G 2 HOH 51 551 2726 HOH HOH C . 
G 2 HOH 52 552 1071 HOH HOH C . 
G 2 HOH 53 553 623  HOH HOH C . 
H 2 HOH 1  501 1181 HOH HOH D . 
H 2 HOH 2  502 120  HOH HOH D . 
H 2 HOH 3  503 1452 HOH HOH D . 
H 2 HOH 4  504 1633 HOH HOH D . 
H 2 HOH 5  505 1007 HOH HOH D . 
H 2 HOH 6  506 945  HOH HOH D . 
H 2 HOH 7  507 570  HOH HOH D . 
H 2 HOH 8  508 2100 HOH HOH D . 
H 2 HOH 9  509 1729 HOH HOH D . 
H 2 HOH 10 510 598  HOH HOH D . 
H 2 HOH 11 511 1663 HOH HOH D . 
H 2 HOH 12 512 1685 HOH HOH D . 
H 2 HOH 13 513 2018 HOH HOH D . 
H 2 HOH 14 514 738  HOH HOH D . 
H 2 HOH 15 515 617  HOH HOH D . 
H 2 HOH 16 516 630  HOH HOH D . 
H 2 HOH 17 517 762  HOH HOH D . 
H 2 HOH 18 518 2011 HOH HOH D . 
H 2 HOH 19 519 1627 HOH HOH D . 
H 2 HOH 20 520 1642 HOH HOH D . 
H 2 HOH 21 521 937  HOH HOH D . 
H 2 HOH 22 522 684  HOH HOH D . 
H 2 HOH 23 523 2290 HOH HOH D . 
H 2 HOH 24 524 2762 HOH HOH D . 
H 2 HOH 25 525 1679 HOH HOH D . 
H 2 HOH 26 526 1089 HOH HOH D . 
H 2 HOH 27 527 1076 HOH HOH D . 
H 2 HOH 28 528 1667 HOH HOH D . 
H 2 HOH 29 529 600  HOH HOH D . 
H 2 HOH 30 530 48   HOH HOH D . 
H 2 HOH 31 531 885  HOH HOH D . 
H 2 HOH 32 532 792  HOH HOH D . 
H 2 HOH 33 533 1725 HOH HOH D . 
H 2 HOH 34 534 2276 HOH HOH D . 
H 2 HOH 35 535 121  HOH HOH D . 
H 2 HOH 36 536 1750 HOH HOH D . 
H 2 HOH 37 537 53   HOH HOH D . 
H 2 HOH 38 538 1693 HOH HOH D . 
H 2 HOH 39 539 580  HOH HOH D . 
H 2 HOH 40 540 1266 HOH HOH D . 
H 2 HOH 41 541 206  HOH HOH D . 
H 2 HOH 42 542 1708 HOH HOH D . 
H 2 HOH 43 543 2583 HOH HOH D . 
H 2 HOH 44 544 1977 HOH HOH D . 
H 2 HOH 45 545 160  HOH HOH D . 
H 2 HOH 46 546 27   HOH HOH D . 
H 2 HOH 47 547 456  HOH HOH D . 
H 2 HOH 48 548 657  HOH HOH D . 
H 2 HOH 49 549 1772 HOH HOH D . 
H 2 HOH 50 550 611  HOH HOH D . 
H 2 HOH 51 551 1942 HOH HOH D . 
H 2 HOH 52 552 1699 HOH HOH D . 
H 2 HOH 53 553 12   HOH HOH D . 
H 2 HOH 54 554 1828 HOH HOH D . 
H 2 HOH 55 555 1141 HOH HOH D . 
H 2 HOH 56 556 1825 HOH HOH D . 
H 2 HOH 57 557 894  HOH HOH D . 
H 2 HOH 58 558 699  HOH HOH D . 
H 2 HOH 59 559 769  HOH HOH D . 
H 2 HOH 60 560 1800 HOH HOH D . 
H 2 HOH 61 561 1911 HOH HOH D . 
H 2 HOH 62 562 2248 HOH HOH D . 
H 2 HOH 63 563 1740 HOH HOH D . 
H 2 HOH 64 564 2619 HOH HOH D . 
H 2 HOH 65 565 2508 HOH HOH D . 
H 2 HOH 66 566 1499 HOH HOH D . 
H 2 HOH 67 567 2311 HOH HOH D . 
H 2 HOH 68 568 1674 HOH HOH D . 
H 2 HOH 69 569 49   HOH HOH D . 
H 2 HOH 70 570 602  HOH HOH D . 
H 2 HOH 71 571 2360 HOH HOH D . 
H 2 HOH 72 572 1673 HOH HOH D . 
H 2 HOH 73 573 2380 HOH HOH D . 
H 2 HOH 74 574 1018 HOH HOH D . 
H 2 HOH 75 575 2250 HOH HOH D . 
H 2 HOH 76 576 2240 HOH HOH D . 
H 2 HOH 77 577 2555 HOH HOH D . 
H 2 HOH 78 578 2328 HOH HOH D . 
H 2 HOH 79 579 2435 HOH HOH D . 
H 2 HOH 80 580 1818 HOH HOH D . 
H 2 HOH 81 581 1095 HOH HOH D . 
H 2 HOH 82 582 2225 HOH HOH D . 
H 2 HOH 83 583 2607 HOH HOH D . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1   1 Y 1 A ARG 19  ? CG  ? A ARG 19  CG  
2   1 Y 1 A ARG 19  ? CD  ? A ARG 19  CD  
3   1 Y 1 A ARG 19  ? NE  ? A ARG 19  NE  
4   1 Y 1 A ARG 19  ? CZ  ? A ARG 19  CZ  
5   1 Y 1 A ARG 19  ? NH1 ? A ARG 19  NH1 
6   1 Y 1 A ARG 19  ? NH2 ? A ARG 19  NH2 
7   1 Y 1 A ARG 239 ? CG  ? A ARG 239 CG  
8   1 Y 1 A ARG 239 ? CD  ? A ARG 239 CD  
9   1 Y 1 A ARG 239 ? NE  ? A ARG 239 NE  
10  1 Y 1 A ARG 239 ? CZ  ? A ARG 239 CZ  
11  1 Y 1 A ARG 239 ? NH1 ? A ARG 239 NH1 
12  1 Y 1 A ARG 239 ? NH2 ? A ARG 239 NH2 
13  1 Y 1 A ARG 243 ? CG  ? A ARG 243 CG  
14  1 Y 1 A ARG 243 ? CD  ? A ARG 243 CD  
15  1 Y 1 A ARG 243 ? NE  ? A ARG 243 NE  
16  1 Y 1 A ARG 243 ? CZ  ? A ARG 243 CZ  
17  1 Y 1 A ARG 243 ? NH1 ? A ARG 243 NH1 
18  1 Y 1 A ARG 243 ? NH2 ? A ARG 243 NH2 
19  1 Y 1 A ARG 319 ? CG  ? A ARG 319 CG  
20  1 Y 1 A ARG 319 ? CD  ? A ARG 319 CD  
21  1 Y 1 A ARG 319 ? NE  ? A ARG 319 NE  
22  1 Y 1 A ARG 319 ? CZ  ? A ARG 319 CZ  
23  1 Y 1 A ARG 319 ? NH1 ? A ARG 319 NH1 
24  1 Y 1 A ARG 319 ? NH2 ? A ARG 319 NH2 
25  1 Y 1 A ARG 337 ? CG  ? A ARG 337 CG  
26  1 Y 1 A ARG 337 ? CD  ? A ARG 337 CD  
27  1 Y 1 A ARG 337 ? NE  ? A ARG 337 NE  
28  1 Y 1 A ARG 337 ? CZ  ? A ARG 337 CZ  
29  1 Y 1 A ARG 337 ? NH1 ? A ARG 337 NH1 
30  1 Y 1 A ARG 337 ? NH2 ? A ARG 337 NH2 
31  1 Y 1 A ARG 383 ? CG  ? A ARG 383 CG  
32  1 Y 1 A ARG 383 ? CD  ? A ARG 383 CD  
33  1 Y 1 A ARG 383 ? NE  ? A ARG 383 NE  
34  1 Y 1 A ARG 383 ? CZ  ? A ARG 383 CZ  
35  1 Y 1 A ARG 383 ? NH1 ? A ARG 383 NH1 
36  1 Y 1 A ARG 383 ? NH2 ? A ARG 383 NH2 
37  1 Y 1 A ASP 384 ? CG  ? A ASP 384 CG  
38  1 Y 1 A ASP 384 ? OD1 ? A ASP 384 OD1 
39  1 Y 1 A ASP 384 ? OD2 ? A ASP 384 OD2 
40  1 Y 1 A ARG 433 ? CG  ? A ARG 433 CG  
41  1 Y 1 A ARG 433 ? CD  ? A ARG 433 CD  
42  1 Y 1 A ARG 433 ? NE  ? A ARG 433 NE  
43  1 Y 1 A ARG 433 ? CZ  ? A ARG 433 CZ  
44  1 Y 1 A ARG 433 ? NH1 ? A ARG 433 NH1 
45  1 Y 1 A ARG 433 ? NH2 ? A ARG 433 NH2 
46  1 Y 1 B ARG 46  ? CG  ? B ARG 46  CG  
47  1 Y 1 B ARG 46  ? CD  ? B ARG 46  CD  
48  1 Y 1 B ARG 46  ? NE  ? B ARG 46  NE  
49  1 Y 1 B ARG 46  ? CZ  ? B ARG 46  CZ  
50  1 Y 1 B ARG 46  ? NH1 ? B ARG 46  NH1 
51  1 Y 1 B ARG 46  ? NH2 ? B ARG 46  NH2 
52  1 Y 1 B ARG 337 ? CG  ? B ARG 337 CG  
53  1 Y 1 B ARG 337 ? CD  ? B ARG 337 CD  
54  1 Y 1 B ARG 337 ? NE  ? B ARG 337 NE  
55  1 Y 1 B ARG 337 ? CZ  ? B ARG 337 CZ  
56  1 Y 1 B ARG 337 ? NH1 ? B ARG 337 NH1 
57  1 Y 1 B ARG 337 ? NH2 ? B ARG 337 NH2 
58  1 Y 1 B GLU 340 ? CG  ? B GLU 340 CG  
59  1 Y 1 B GLU 340 ? CD  ? B GLU 340 CD  
60  1 Y 1 B GLU 340 ? OE1 ? B GLU 340 OE1 
61  1 Y 1 B GLU 340 ? OE2 ? B GLU 340 OE2 
62  1 Y 1 B GLU 344 ? CG  ? B GLU 344 CG  
63  1 Y 1 B GLU 344 ? CD  ? B GLU 344 CD  
64  1 Y 1 B GLU 344 ? OE1 ? B GLU 344 OE1 
65  1 Y 1 B GLU 344 ? OE2 ? B GLU 344 OE2 
66  1 Y 1 B ARG 383 ? CG  ? B ARG 383 CG  
67  1 Y 1 B ARG 383 ? CD  ? B ARG 383 CD  
68  1 Y 1 B ARG 383 ? NE  ? B ARG 383 NE  
69  1 Y 1 B ARG 383 ? CZ  ? B ARG 383 CZ  
70  1 Y 1 B ARG 383 ? NH1 ? B ARG 383 NH1 
71  1 Y 1 B ARG 383 ? NH2 ? B ARG 383 NH2 
72  1 Y 1 B SER 409 ? OG  ? B SER 409 OG  
73  1 Y 1 B GLU 410 ? CG  ? B GLU 410 CG  
74  1 Y 1 B GLU 410 ? CD  ? B GLU 410 CD  
75  1 Y 1 B GLU 410 ? OE1 ? B GLU 410 OE1 
76  1 Y 1 B GLU 410 ? OE2 ? B GLU 410 OE2 
77  1 Y 1 B TYR 411 ? CG  ? B TYR 411 CG  
78  1 Y 1 B TYR 411 ? CD1 ? B TYR 411 CD1 
79  1 Y 1 B TYR 411 ? CD2 ? B TYR 411 CD2 
80  1 Y 1 B TYR 411 ? CE1 ? B TYR 411 CE1 
81  1 Y 1 B TYR 411 ? CE2 ? B TYR 411 CE2 
82  1 Y 1 B TYR 411 ? CZ  ? B TYR 411 CZ  
83  1 Y 1 B TYR 411 ? OH  ? B TYR 411 OH  
84  1 Y 1 B ARG 433 ? CG  ? B ARG 433 CG  
85  1 Y 1 B ARG 433 ? CD  ? B ARG 433 CD  
86  1 Y 1 B ARG 433 ? NE  ? B ARG 433 NE  
87  1 Y 1 B ARG 433 ? CZ  ? B ARG 433 CZ  
88  1 Y 1 B ARG 433 ? NH1 ? B ARG 433 NH1 
89  1 Y 1 B ARG 433 ? NH2 ? B ARG 433 NH2 
90  1 Y 1 C ARG 25  ? CG  ? C ARG 25  CG  
91  1 Y 1 C ARG 25  ? CD  ? C ARG 25  CD  
92  1 Y 1 C ARG 25  ? NE  ? C ARG 25  NE  
93  1 Y 1 C ARG 25  ? CZ  ? C ARG 25  CZ  
94  1 Y 1 C ARG 25  ? NH1 ? C ARG 25  NH1 
95  1 Y 1 C ARG 25  ? NH2 ? C ARG 25  NH2 
96  1 Y 1 C ARG 26  ? CG  ? C ARG 26  CG  
97  1 Y 1 C ARG 26  ? CD  ? C ARG 26  CD  
98  1 Y 1 C ARG 26  ? NE  ? C ARG 26  NE  
99  1 Y 1 C ARG 26  ? CZ  ? C ARG 26  CZ  
100 1 Y 1 C ARG 26  ? NH1 ? C ARG 26  NH1 
101 1 Y 1 C ARG 26  ? NH2 ? C ARG 26  NH2 
102 1 Y 1 C ARG 296 ? CG  ? C ARG 296 CG  
103 1 Y 1 C ARG 296 ? CD  ? C ARG 296 CD  
104 1 Y 1 C ARG 296 ? NE  ? C ARG 296 NE  
105 1 Y 1 C ARG 296 ? CZ  ? C ARG 296 CZ  
106 1 Y 1 C ARG 296 ? NH1 ? C ARG 296 NH1 
107 1 Y 1 C ARG 296 ? NH2 ? C ARG 296 NH2 
108 1 Y 1 C GLU 410 ? CG  ? C GLU 410 CG  
109 1 Y 1 C GLU 410 ? CD  ? C GLU 410 CD  
110 1 Y 1 C GLU 410 ? OE1 ? C GLU 410 OE1 
111 1 Y 1 C GLU 410 ? OE2 ? C GLU 410 OE2 
112 1 Y 1 C TYR 411 ? CG  ? C TYR 411 CG  
113 1 Y 1 C TYR 411 ? CD1 ? C TYR 411 CD1 
114 1 Y 1 C TYR 411 ? CD2 ? C TYR 411 CD2 
115 1 Y 1 C TYR 411 ? CE1 ? C TYR 411 CE1 
116 1 Y 1 C TYR 411 ? CE2 ? C TYR 411 CE2 
117 1 Y 1 C TYR 411 ? CZ  ? C TYR 411 CZ  
118 1 Y 1 C TYR 411 ? OH  ? C TYR 411 OH  
119 1 Y 1 C ARG 433 ? CG  ? C ARG 433 CG  
120 1 Y 1 C ARG 433 ? CD  ? C ARG 433 CD  
121 1 Y 1 C ARG 433 ? NE  ? C ARG 433 NE  
122 1 Y 1 C ARG 433 ? CZ  ? C ARG 433 CZ  
123 1 Y 1 C ARG 433 ? NH1 ? C ARG 433 NH1 
124 1 Y 1 C ARG 433 ? NH2 ? C ARG 433 NH2 
125 1 Y 1 C ARG 462 ? CG  ? C ARG 462 CG  
126 1 Y 1 C ARG 462 ? CD  ? C ARG 462 CD  
127 1 Y 1 C ARG 462 ? NE  ? C ARG 462 NE  
128 1 Y 1 C ARG 462 ? CZ  ? C ARG 462 CZ  
129 1 Y 1 C ARG 462 ? NH1 ? C ARG 462 NH1 
130 1 Y 1 C ARG 462 ? NH2 ? C ARG 462 NH2 
131 1 Y 1 D TYR 411 ? CG  ? D TYR 411 CG  
132 1 Y 1 D TYR 411 ? CD1 ? D TYR 411 CD1 
133 1 Y 1 D TYR 411 ? CD2 ? D TYR 411 CD2 
134 1 Y 1 D TYR 411 ? CE1 ? D TYR 411 CE1 
135 1 Y 1 D TYR 411 ? CE2 ? D TYR 411 CE2 
136 1 Y 1 D TYR 411 ? CZ  ? D TYR 411 CZ  
137 1 Y 1 D TYR 411 ? OH  ? D TYR 411 OH  
138 1 Y 1 D ARG 462 ? CG  ? D ARG 462 CG  
139 1 Y 1 D ARG 462 ? CD  ? D ARG 462 CD  
140 1 Y 1 D ARG 462 ? NE  ? D ARG 462 NE  
141 1 Y 1 D ARG 462 ? CZ  ? D ARG 462 CZ  
142 1 Y 1 D ARG 462 ? NH1 ? D ARG 462 NH1 
143 1 Y 1 D ARG 462 ? NH2 ? D ARG 462 NH2 
144 1 Y 1 D PHE 463 ? CG  ? D PHE 463 CG  
145 1 Y 1 D PHE 463 ? CD1 ? D PHE 463 CD1 
146 1 Y 1 D PHE 463 ? CD2 ? D PHE 463 CD2 
147 1 Y 1 D PHE 463 ? CE1 ? D PHE 463 CE1 
148 1 Y 1 D PHE 463 ? CE2 ? D PHE 463 CE2 
149 1 Y 1 D PHE 463 ? CZ  ? D PHE 463 CZ  
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? REFMAC   ? ? ? 5.8.0425 1 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? Aimless  ? ? ? .        2 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? HKL-2000 ? ? ? .        3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER   ? ? ? .        4 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8ZCX 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     102.669 
_cell.length_a_esd                 ? 
_cell.length_b                     146.744 
_cell.length_b_esd                 ? 
_cell.length_c                     149.528 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        16 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8ZCX 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                19 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 21 21 21' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8ZCX 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.82 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          56.41 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              6.0 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '0.1M MMT, pH6.0, 25% PEG1500, 10% glycerol' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            298 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER X 16M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2024-03-15 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.9791 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'SSRF BEAMLINE BL10U2' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.9791 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   BL10U2 
_diffrn_source.pdbx_synchrotron_site       SSRF 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       8ZCX 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.44 
_reflns.d_resolution_low                               50 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     83594 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           98.7 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                17.5 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          12.8 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.999 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              ? 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.44 
_reflns_shell.d_res_low                                     2.5 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           1.5 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             5452 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               9.0 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.596 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            -0.83 
_refine.aniso_B[1][2]                            0.00 
_refine.aniso_B[1][3]                            0.00 
_refine.aniso_B[2][2]                            2.49 
_refine.aniso_B[2][3]                            -0.00 
_refine.aniso_B[3][3]                            -1.67 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               61.343 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               0.943 
_refine.correlation_coeff_Fo_to_Fc_free          0.923 
_refine.details                                  'HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS' 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8ZCX 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.44 
_refine.ls_d_res_low                             50 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     78549 
_refine.ls_number_reflns_R_free                  4316 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    97.92 
_refine.ls_percent_reflns_R_free                 5.2 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.22354 
_refine.ls_R_factor_R_free                       0.25205 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.22197 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    MASK 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               THROUGHOUT 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'MAXIMUM LIKELIHOOD' 
_refine.pdbx_R_Free_selection_details            RANDOM 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       0.462 
_refine.pdbx_overall_ESU_R_Free                  0.270 
_refine.pdbx_solvent_vdw_probe_radii             1.20 
_refine.pdbx_solvent_ion_probe_radii             0.80 
_refine.pdbx_solvent_shrinkage_radii             0.80 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             10.799 
_refine.overall_SU_ML                            0.231 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         1 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.44 
_refine_hist.d_res_low                        50 
_refine_hist.number_atoms_solvent             192 
_refine_hist.number_atoms_total               14061 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        13869 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         0 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.010  0.012  14523 ? r_bond_refined_d             ? ? 
'X-RAY DIFFRACTION' ? 0.002  0.016  13907 ? r_bond_other_d               ? ? 
'X-RAY DIFFRACTION' ? 0.997  1.817  19715 ? r_angle_refined_deg          ? ? 
'X-RAY DIFFRACTION' ? 0.363  1.749  31833 ? r_angle_other_deg            ? ? 
'X-RAY DIFFRACTION' ? 6.417  5.000  1860  ? r_dihedral_angle_1_deg       ? ? 
'X-RAY DIFFRACTION' ? 14.848 5.000  149   ? r_dihedral_angle_2_deg       ? ? 
'X-RAY DIFFRACTION' ? 19.734 10.000 2272  ? r_dihedral_angle_3_deg       ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_dihedral_angle_4_deg       ? ? 
'X-RAY DIFFRACTION' ? 0.053  0.200  2192  ? r_chiral_restr               ? ? 
'X-RAY DIFFRACTION' ? 0.006  0.020  17790 ? r_gen_planes_refined         ? ? 
'X-RAY DIFFRACTION' ? 0.001  0.020  3466  ? r_gen_planes_other           ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_nbd_refined                ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_nbd_other                  ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_nbtor_refined              ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_nbtor_other                ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_xyhbond_nbd_refined        ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_xyhbond_nbd_other          ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_metal_ion_refined          ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_metal_ion_other            ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_vdw_refined       ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_vdw_other         ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_hbond_refined     ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_hbond_other       ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_metal_ion_refined ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_metal_ion_other   ? ? 
'X-RAY DIFFRACTION' ? 5.593  5.938  7470  ? r_mcbond_it                  ? ? 
'X-RAY DIFFRACTION' ? 5.593  5.938  7470  ? r_mcbond_other               ? ? 
'X-RAY DIFFRACTION' ? 8.688  10.671 9320  ? r_mcangle_it                 ? ? 
'X-RAY DIFFRACTION' ? 8.687  10.671 9321  ? r_mcangle_other              ? ? 
'X-RAY DIFFRACTION' ? 5.867  6.573  7053  ? r_scbond_it                  ? ? 
'X-RAY DIFFRACTION' ? 5.867  6.573  7054  ? r_scbond_other               ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_scangle_it                 ? ? 
'X-RAY DIFFRACTION' ? 9.342  11.766 10396 ? r_scangle_other              ? ? 
'X-RAY DIFFRACTION' ? 16.828 72.06  59561 ? r_long_range_B_refined       ? ? 
'X-RAY DIFFRACTION' ? 16.834 72.05  59502 ? r_long_range_B_other         ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_rigid_bond_restr           ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_sphericity_free            ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_sphericity_bonded          ? ? 
# 
_refine_ls_shell.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_ls_shell.d_res_high                       2.440 
_refine_ls_shell.d_res_low                        2.503 
_refine_ls_shell.number_reflns_all                ? 
_refine_ls_shell.number_reflns_obs                ? 
_refine_ls_shell.number_reflns_R_free             225 
_refine_ls_shell.number_reflns_R_work             4886 
_refine_ls_shell.percent_reflns_obs               82.54 
_refine_ls_shell.percent_reflns_R_free            ? 
_refine_ls_shell.R_factor_all                     ? 
_refine_ls_shell.R_factor_obs                     ? 
_refine_ls_shell.R_factor_R_free_error            ? 
_refine_ls_shell.R_factor_R_work                  0.339 
_refine_ls_shell.redundancy_reflns_all            ? 
_refine_ls_shell.redundancy_reflns_obs            ? 
_refine_ls_shell.wR_factor_all                    ? 
_refine_ls_shell.wR_factor_obs                    ? 
_refine_ls_shell.wR_factor_R_free                 ? 
_refine_ls_shell.wR_factor_R_work                 ? 
_refine_ls_shell.pdbx_R_complete                  ? 
_refine_ls_shell.pdbx_total_number_of_bins_used   20 
_refine_ls_shell.pdbx_phase_error                 ? 
_refine_ls_shell.pdbx_fsc_work                    ? 
_refine_ls_shell.pdbx_fsc_free                    ? 
_refine_ls_shell.R_factor_R_free                  0.364 
# 
_struct.entry_id                     8ZCX 
_struct.title                        'Crystal Structure of a novel Aldehyde Dehydrogenase from Klebsiella pneumoniae' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8ZCX 
_struct_keywords.text            'catalysis, Aldehyde dehydrogenase, OXIDOREDUCTASE' 
_struct_keywords.pdbx_keywords   OXIDOREDUCTASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 1 ? 
D N N 1 ? 
E N N 2 ? 
F N N 2 ? 
G N N 2 ? 
H N N 2 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    A0A069Q1D5_PSEAI 
_struct_ref.pdbx_db_accession          A0A069Q1D5 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MSDSRYTDLGLQPLAGEWRHGRAGRRLKVSNPFDGSLLLEIEQADRDDLDAAYAKAAEVQPAWAALGPSARAAVLYKAVE
VFDRRHEEIVDWIIRESGSTRLKAEIEWGAARAITLESASFPARVHGRIVESDVPGKESRVYRSAIGVVGVISPWNFPLH
LTQRSIAPALALGNAVVVKPASDTPVCGGLLLARIFEEAGLPAGLFSVVVGPGSEIGDAFVEHPVPGLVTFTGSTPVGRN
IGRIASGGAHLKHVALELGGNSPFVVLGDADLEQAVNAAVFGKFLHQGQICMAINRIIVEDSLYDAFAARFVERVKGLRV
GDPQRADTAVGPIVNARQLEGLLEKIRLARQEGAKPLYEGGVDGQLLAPHVFGEVTATMEIARDEIFGPLVGLLRARDEA
HALELANASEYGLSSAVFSRDLERAVRFARQLRAGMTHVNDIPVNDEANAPFGGEKNSGLGRFNGDWAIEEFTTDHWISV
QHAPRQYPF
;
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8ZCX A 1 ? 489 ? A0A069Q1D5 1 ? 489 ? 1 489 
2 1 8ZCX B 1 ? 489 ? A0A069Q1D5 1 ? 489 ? 1 489 
3 1 8ZCX C 1 ? 489 ? A0A069Q1D5 1 ? 489 ? 1 489 
4 1 8ZCX D 1 ? 489 ? A0A069Q1D5 1 ? 489 ? 1 489 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8ZCX SER A 277 ? UNP A0A069Q1D5 ASN 277 conflict 277 1 
2 8ZCX SER B 277 ? UNP A0A069Q1D5 ASN 277 conflict 277 2 
3 8ZCX SER C 277 ? UNP A0A069Q1D5 ASN 277 conflict 277 3 
4 8ZCX SER D 277 ? UNP A0A069Q1D5 ASN 277 conflict 277 4 
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 author_and_software_defined_assembly PISA tetrameric 4 
2 author_and_software_defined_assembly PISA dimeric    2 
3 author_and_software_defined_assembly PISA dimeric    2 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 12070 ? 
1 MORE         -52   ? 
1 'SSA (A^2)'  67150 ? 
2 'ABSA (A^2)' 3120  ? 
2 MORE         -15   ? 
2 'SSA (A^2)'  36070 ? 
3 'ABSA (A^2)' 4070  ? 
3 MORE         -14   ? 
3 'SSA (A^2)'  35960 ? 
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 1 A,B,C,D,E,F,G,H 
2 1 A,D,E,H         
3 1 B,C,F,G         
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 ASP A 45  ? LEU A 66  ? ASP A 45  LEU A 66  1 ? 22 
HELX_P HELX_P2  AA2 GLY A 67  ? ARG A 85  ? GLY A 67  ARG A 85  1 ? 19 
HELX_P HELX_P3  AA3 ARG A 85  ? GLY A 98  ? ARG A 85  GLY A 98  1 ? 14 
HELX_P HELX_P4  AA4 THR A 100 ? ALA A 119 ? THR A 100 ALA A 119 1 ? 20 
HELX_P HELX_P5  AA5 SER A 120 ? VAL A 125 ? SER A 120 VAL A 125 1 ? 6  
HELX_P HELX_P6  AA6 PHE A 157 ? LEU A 172 ? PHE A 157 LEU A 172 1 ? 16 
HELX_P HELX_P7  AA7 GLY A 189 ? ALA A 199 ? GLY A 189 ALA A 199 1 ? 11 
HELX_P HELX_P8  AA8 PRO A 212 ? HIS A 223 ? PRO A 212 HIS A 223 1 ? 12 
HELX_P HELX_P9  AA9 SER A 234 ? GLY A 248 ? SER A 234 GLY A 248 1 ? 15 
HELX_P HELX_P10 AB1 ASP A 271 ? LEU A 285 ? ASP A 271 LEU A 285 1 ? 15 
HELX_P HELX_P11 AB2 ASP A 301 ? LEU A 318 ? ASP A 301 LEU A 318 1 ? 18 
HELX_P HELX_P12 AB3 ASN A 335 ? GLY A 353 ? ASN A 335 GLY A 353 1 ? 19 
HELX_P HELX_P13 AB4 MET A 379 ? ASP A 384 ? MET A 379 ASP A 384 1 ? 6  
HELX_P HELX_P14 AB5 ASP A 398 ? SER A 409 ? ASP A 398 SER A 409 1 ? 12 
HELX_P HELX_P15 AB6 ASP A 421 ? LEU A 432 ? ASP A 421 LEU A 432 1 ? 12 
HELX_P HELX_P16 AB7 PHE A 463 ? PHE A 472 ? PHE A 463 PHE A 472 1 ? 10 
HELX_P HELX_P17 AB8 ASP B 45  ? LEU B 66  ? ASP B 45  LEU B 66  1 ? 22 
HELX_P HELX_P18 AB9 GLY B 67  ? ARG B 85  ? GLY B 67  ARG B 85  1 ? 19 
HELX_P HELX_P19 AC1 ARG B 85  ? GLY B 98  ? ARG B 85  GLY B 98  1 ? 14 
HELX_P HELX_P20 AC2 THR B 100 ? ALA B 119 ? THR B 100 ALA B 119 1 ? 20 
HELX_P HELX_P21 AC3 SER B 120 ? VAL B 125 ? SER B 120 VAL B 125 5 ? 6  
HELX_P HELX_P22 AC4 PHE B 157 ? LEU B 172 ? PHE B 157 LEU B 172 1 ? 16 
HELX_P HELX_P23 AC5 GLY B 189 ? ALA B 199 ? GLY B 189 ALA B 199 1 ? 11 
HELX_P HELX_P24 AC6 ILE B 216 ? HIS B 223 ? ILE B 216 HIS B 223 1 ? 8  
HELX_P HELX_P25 AC7 SER B 234 ? GLY B 248 ? SER B 234 GLY B 248 1 ? 15 
HELX_P HELX_P26 AC8 ASP B 271 ? PHE B 284 ? ASP B 271 PHE B 284 1 ? 14 
HELX_P HELX_P27 AC9 ASP B 301 ? LEU B 318 ? ASP B 301 LEU B 318 1 ? 18 
HELX_P HELX_P28 AD1 ASN B 335 ? GLY B 353 ? ASN B 335 GLY B 353 1 ? 19 
HELX_P HELX_P29 AD2 MET B 379 ? ASP B 384 ? MET B 379 ASP B 384 1 ? 6  
HELX_P HELX_P30 AD3 ASP B 398 ? ASN B 407 ? ASP B 398 ASN B 407 1 ? 10 
HELX_P HELX_P31 AD4 ASP B 421 ? LEU B 432 ? ASP B 421 LEU B 432 1 ? 12 
HELX_P HELX_P32 AD5 PHE B 463 ? PHE B 472 ? PHE B 463 PHE B 472 1 ? 10 
HELX_P HELX_P33 AD6 ASP C 45  ? LEU C 66  ? ASP C 45  LEU C 66  1 ? 22 
HELX_P HELX_P34 AD7 GLY C 67  ? ARG C 85  ? GLY C 67  ARG C 85  1 ? 19 
HELX_P HELX_P35 AD8 ARG C 85  ? GLY C 98  ? ARG C 85  GLY C 98  1 ? 14 
HELX_P HELX_P36 AD9 THR C 100 ? ALA C 119 ? THR C 100 ALA C 119 1 ? 20 
HELX_P HELX_P37 AE1 SER C 120 ? ARG C 124 ? SER C 120 ARG C 124 5 ? 5  
HELX_P HELX_P38 AE2 PHE C 157 ? LEU C 172 ? PHE C 157 LEU C 172 1 ? 16 
HELX_P HELX_P39 AE3 GLY C 188 ? ALA C 199 ? GLY C 188 ALA C 199 1 ? 12 
HELX_P HELX_P40 AE4 GLU C 215 ? HIS C 223 ? GLU C 215 HIS C 223 1 ? 9  
HELX_P HELX_P41 AE5 SER C 234 ? GLY C 248 ? SER C 234 GLY C 248 1 ? 15 
HELX_P HELX_P42 AE6 ASP C 271 ? PHE C 284 ? ASP C 271 PHE C 284 1 ? 14 
HELX_P HELX_P43 AE7 ASP C 301 ? GLY C 317 ? ASP C 301 GLY C 317 1 ? 17 
HELX_P HELX_P44 AE8 ASN C 335 ? GLY C 353 ? ASN C 335 GLY C 353 1 ? 19 
HELX_P HELX_P45 AE9 MET C 379 ? ASP C 384 ? MET C 379 ASP C 384 1 ? 6  
HELX_P HELX_P46 AF1 ASP C 398 ? ALA C 408 ? ASP C 398 ALA C 408 1 ? 11 
HELX_P HELX_P47 AF2 ASP C 421 ? GLN C 431 ? ASP C 421 GLN C 431 1 ? 11 
HELX_P HELX_P48 AF3 ASN C 464 ? PHE C 472 ? ASN C 464 PHE C 472 1 ? 9  
HELX_P HELX_P49 AF4 ASP D 45  ? LEU D 66  ? ASP D 45  LEU D 66  1 ? 22 
HELX_P HELX_P50 AF5 GLY D 67  ? ARG D 85  ? GLY D 67  ARG D 85  1 ? 19 
HELX_P HELX_P51 AF6 ARG D 85  ? GLY D 98  ? ARG D 85  GLY D 98  1 ? 14 
HELX_P HELX_P52 AF7 THR D 100 ? ALA D 119 ? THR D 100 ALA D 119 1 ? 20 
HELX_P HELX_P53 AF8 SER D 120 ? VAL D 125 ? SER D 120 VAL D 125 1 ? 6  
HELX_P HELX_P54 AF9 PHE D 157 ? LEU D 172 ? PHE D 157 LEU D 172 1 ? 16 
HELX_P HELX_P55 AG1 GLY D 189 ? ALA D 199 ? GLY D 189 ALA D 199 1 ? 11 
HELX_P HELX_P56 AG2 PRO D 212 ? HIS D 223 ? PRO D 212 HIS D 223 1 ? 12 
HELX_P HELX_P57 AG3 SER D 234 ? GLY D 248 ? SER D 234 GLY D 248 1 ? 15 
HELX_P HELX_P58 AG4 ASP D 271 ? PHE D 284 ? ASP D 271 PHE D 284 1 ? 14 
HELX_P HELX_P59 AG5 ASP D 301 ? GLY D 317 ? ASP D 301 GLY D 317 1 ? 17 
HELX_P HELX_P60 AG6 ASN D 335 ? GLU D 352 ? ASN D 335 GLU D 352 1 ? 18 
HELX_P HELX_P61 AG7 MET D 379 ? ASP D 384 ? MET D 379 ASP D 384 1 ? 6  
HELX_P HELX_P62 AG8 ASP D 398 ? SER D 409 ? ASP D 398 SER D 409 1 ? 12 
HELX_P HELX_P63 AG9 ASP D 421 ? LEU D 432 ? ASP D 421 LEU D 432 1 ? 12 
HELX_P HELX_P64 AH1 ASN D 464 ? PHE D 472 ? ASN D 464 PHE D 472 1 ? 9  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 2  ? 
AA2 ? 2  ? 
AA3 ? 20 ? 
AA4 ? 5  ? 
AA5 ? 20 ? 
AA6 ? 2  ? 
AA7 ? 2  ? 
AA8 ? 2  ? 
AA9 ? 5  ? 
AB1 ? 2  ? 
AB2 ? 2  ? 
AB3 ? 2  ? 
AB4 ? 5  ? 
AB5 ? 2  ? 
AB6 ? 2  ? 
AB7 ? 2  ? 
AB8 ? 5  ? 
AB9 ? 2  ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1  2  ? anti-parallel 
AA2 1  2  ? anti-parallel 
AA3 1  2  ? anti-parallel 
AA3 2  3  ? parallel      
AA3 3  4  ? parallel      
AA3 4  5  ? parallel      
AA3 5  6  ? parallel      
AA3 6  7  ? parallel      
AA3 7  8  ? parallel      
AA3 8  9  ? anti-parallel 
AA3 9  10 ? anti-parallel 
AA3 10 11 ? anti-parallel 
AA3 11 12 ? anti-parallel 
AA3 12 13 ? anti-parallel 
AA3 13 14 ? parallel      
AA3 14 15 ? parallel      
AA3 15 16 ? parallel      
AA3 16 17 ? parallel      
AA3 17 18 ? parallel      
AA3 18 19 ? parallel      
AA3 19 20 ? anti-parallel 
AA4 1  2  ? parallel      
AA4 2  3  ? parallel      
AA4 3  4  ? parallel      
AA4 4  5  ? parallel      
AA5 1  2  ? anti-parallel 
AA5 2  3  ? parallel      
AA5 3  4  ? parallel      
AA5 4  5  ? parallel      
AA5 5  6  ? parallel      
AA5 6  7  ? parallel      
AA5 7  8  ? parallel      
AA5 8  9  ? anti-parallel 
AA5 9  10 ? anti-parallel 
AA5 10 11 ? anti-parallel 
AA5 11 12 ? anti-parallel 
AA5 12 13 ? anti-parallel 
AA5 13 14 ? parallel      
AA5 14 15 ? parallel      
AA5 15 16 ? parallel      
AA5 16 17 ? parallel      
AA5 17 18 ? parallel      
AA5 18 19 ? parallel      
AA5 19 20 ? anti-parallel 
AA6 1  2  ? anti-parallel 
AA7 1  2  ? anti-parallel 
AA8 1  2  ? anti-parallel 
AA9 1  2  ? parallel      
AA9 2  3  ? parallel      
AA9 3  4  ? parallel      
AA9 4  5  ? parallel      
AB1 1  2  ? anti-parallel 
AB2 1  2  ? anti-parallel 
AB3 1  2  ? anti-parallel 
AB4 1  2  ? parallel      
AB4 2  3  ? parallel      
AB4 3  4  ? parallel      
AB4 4  5  ? parallel      
AB5 1  2  ? anti-parallel 
AB6 1  2  ? anti-parallel 
AB7 1  2  ? anti-parallel 
AB8 1  2  ? parallel      
AB8 2  3  ? parallel      
AB8 3  4  ? parallel      
AB8 4  5  ? parallel      
AB9 1  2  ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1  GLN A 12  ? LEU A 14  ? GLN A 12  LEU A 14  
AA1 2  GLU A 17  ? ARG A 19  ? GLU A 17  ARG A 19  
AA2 1  ARG A 26  ? SER A 30  ? ARG A 26  SER A 30  
AA2 2  LEU A 37  ? GLU A 42  ? LEU A 37  GLU A 42  
AA3 1  LYS B 355 ? TYR B 358 ? LYS B 355 TYR B 358 
AA3 2  HIS B 370 ? VAL B 375 ? HIS B 370 VAL B 375 
AA3 3  LEU B 390 ? ALA B 396 ? LEU B 390 ALA B 396 
AA3 4  ARG B 296 ? GLU B 300 ? ARG B 296 GLU B 300 
AA3 5  PRO B 263 ? VAL B 266 ? PRO B 263 VAL B 266 
AA3 6  SER B 414 ? PHE B 418 ? SER B 414 PHE B 418 
AA3 7  MET B 436 ? VAL B 439 ? MET B 436 VAL B 439 
AA3 8  THR C 473 ? GLN C 481 ? THR C 473 GLN C 481 
AA3 9  LYS C 137 ? ALA C 145 ? LYS C 137 ALA C 145 
AA3 10 HIS C 126 ? VAL C 130 ? HIS C 126 VAL C 130 
AA3 11 GLY A 127 ? VAL A 130 ? GLY A 127 VAL A 130 
AA3 12 LYS A 137 ? ALA A 145 ? LYS A 137 ALA A 145 
AA3 13 THR A 473 ? GLN A 481 ? THR A 473 GLN A 481 
AA3 14 MET D 436 ? VAL D 439 ? MET D 436 VAL D 439 
AA3 15 ALA D 416 ? PHE D 418 ? ALA D 416 PHE D 418 
AA3 16 PRO D 263 ? VAL D 266 ? PRO D 263 VAL D 266 
AA3 17 ARG D 296 ? GLU D 300 ? ARG D 296 GLU D 300 
AA3 18 LEU D 390 ? ALA D 396 ? LEU D 390 ALA D 396 
AA3 19 HIS D 370 ? VAL D 375 ? HIS D 370 VAL D 375 
AA3 20 LYS D 355 ? GLU D 359 ? LYS D 355 GLU D 359 
AA4 1  PHE A 206 ? VAL A 208 ? PHE A 206 VAL A 208 
AA4 2  ALA A 175 ? LYS A 179 ? ALA A 175 LYS A 179 
AA4 3  VAL A 148 ? ILE A 152 ? VAL A 148 ILE A 152 
AA4 4  LEU A 228 ? GLY A 233 ? LEU A 228 GLY A 233 
AA4 5  HIS A 253 ? LEU A 258 ? HIS A 253 LEU A 258 
AA5 1  LYS A 355 ? GLU A 359 ? LYS A 355 GLU A 359 
AA5 2  HIS A 370 ? VAL A 375 ? HIS A 370 VAL A 375 
AA5 3  LEU A 390 ? ALA A 396 ? LEU A 390 ALA A 396 
AA5 4  ARG A 296 ? GLU A 300 ? ARG A 296 GLU A 300 
AA5 5  PRO A 263 ? VAL A 266 ? PRO A 263 VAL A 266 
AA5 6  ALA A 416 ? PHE A 418 ? ALA A 416 PHE A 418 
AA5 7  MET A 436 ? VAL A 439 ? MET A 436 VAL A 439 
AA5 8  THR D 473 ? GLN D 481 ? THR D 473 GLN D 481 
AA5 9  LYS D 137 ? ALA D 145 ? LYS D 137 ALA D 145 
AA5 10 GLY D 127 ? VAL D 130 ? GLY D 127 VAL D 130 
AA5 11 GLY B 127 ? VAL B 130 ? GLY B 127 VAL B 130 
AA5 12 LYS B 137 ? ALA B 145 ? LYS B 137 ALA B 145 
AA5 13 THR B 473 ? GLN B 481 ? THR B 473 GLN B 481 
AA5 14 MET C 436 ? VAL C 439 ? MET C 436 VAL C 439 
AA5 15 ALA C 416 ? PHE C 418 ? ALA C 416 PHE C 418 
AA5 16 PRO C 263 ? VAL C 266 ? PRO C 263 VAL C 266 
AA5 17 ARG C 296 ? GLU C 300 ? ARG C 296 GLU C 300 
AA5 18 LEU C 390 ? ALA C 396 ? LEU C 390 ALA C 396 
AA5 19 HIS C 370 ? GLY C 373 ? HIS C 370 GLY C 373 
AA5 20 LYS C 355 ? GLU C 359 ? LYS C 355 GLU C 359 
AA6 1  VAL A 362 ? ASP A 363 ? VAL A 362 ASP A 363 
AA6 2  LEU A 366 ? LEU A 367 ? LEU A 366 LEU A 367 
AA7 1  GLN B 12  ? LEU B 14  ? GLN B 12  LEU B 14  
AA7 2  GLU B 17  ? ARG B 19  ? GLU B 17  ARG B 19  
AA8 1  ARG B 26  ? SER B 30  ? ARG B 26  SER B 30  
AA8 2  LEU B 37  ? GLU B 42  ? LEU B 37  GLU B 42  
AA9 1  PHE B 206 ? VAL B 208 ? PHE B 206 VAL B 208 
AA9 2  ALA B 175 ? LYS B 179 ? ALA B 175 LYS B 179 
AA9 3  VAL B 148 ? ILE B 152 ? VAL B 148 ILE B 152 
AA9 4  LEU B 228 ? GLY B 233 ? LEU B 228 GLY B 233 
AA9 5  HIS B 253 ? LEU B 258 ? HIS B 253 LEU B 258 
AB1 1  VAL B 362 ? ASP B 363 ? VAL B 362 ASP B 363 
AB1 2  LEU B 366 ? LEU B 367 ? LEU B 366 LEU B 367 
AB2 1  GLN C 12  ? LEU C 14  ? GLN C 12  LEU C 14  
AB2 2  GLU C 17  ? ARG C 19  ? GLU C 17  ARG C 19  
AB3 1  ARG C 26  ? SER C 30  ? ARG C 26  SER C 30  
AB3 2  LEU C 37  ? GLU C 42  ? LEU C 37  GLU C 42  
AB4 1  PHE C 206 ? VAL C 208 ? PHE C 206 VAL C 208 
AB4 2  ALA C 175 ? LYS C 179 ? ALA C 175 LYS C 179 
AB4 3  VAL C 148 ? ILE C 152 ? VAL C 148 ILE C 152 
AB4 4  LEU C 228 ? GLY C 233 ? LEU C 228 GLY C 233 
AB4 5  HIS C 253 ? LEU C 258 ? HIS C 253 LEU C 258 
AB5 1  VAL C 362 ? ASP C 363 ? VAL C 362 ASP C 363 
AB5 2  LEU C 366 ? LEU C 367 ? LEU C 366 LEU C 367 
AB6 1  GLN D 12  ? LEU D 14  ? GLN D 12  LEU D 14  
AB6 2  GLU D 17  ? ARG D 19  ? GLU D 17  ARG D 19  
AB7 1  ARG D 26  ? SER D 30  ? ARG D 26  SER D 30  
AB7 2  LEU D 37  ? GLU D 42  ? LEU D 37  GLU D 42  
AB8 1  PHE D 206 ? VAL D 208 ? PHE D 206 VAL D 208 
AB8 2  ALA D 175 ? LYS D 179 ? ALA D 175 LYS D 179 
AB8 3  VAL D 148 ? ILE D 152 ? VAL D 148 ILE D 152 
AB8 4  LEU D 228 ? GLY D 233 ? LEU D 228 GLY D 233 
AB8 5  HIS D 253 ? LEU D 258 ? HIS D 253 LEU D 258 
AB9 1  VAL D 362 ? ASP D 363 ? VAL D 362 ASP D 363 
AB9 2  LEU D 366 ? LEU D 367 ? LEU D 366 LEU D 367 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1  2  N GLN A 12  ? N GLN A 12  O ARG A 19  ? O ARG A 19  
AA2 1  2  N LEU A 27  ? N LEU A 27  O ILE A 41  ? O ILE A 41  
AA3 1  2  N LYS B 355 ? N LYS B 355 O GLY B 373 ? O GLY B 373 
AA3 2  3  N PHE B 372 ? N PHE B 372 O VAL B 391 ? O VAL B 391 
AA3 3  4  O LEU B 394 ? O LEU B 394 N ILE B 297 ? N ILE B 297 
AA3 4  5  O ARG B 296 ? O ARG B 296 N PHE B 264 ? N PHE B 264 
AA3 5  6  N VAL B 265 ? N VAL B 265 O ALA B 416 ? O ALA B 416 
AA3 6  7  N VAL B 417 ? N VAL B 417 O HIS B 438 ? O HIS B 438 
AA3 7  8  N THR B 437 ? N THR B 437 O TRP C 477 ? O TRP C 477 
AA3 8  9  O VAL C 480 ? O VAL C 480 N GLU C 138 ? N GLU C 138 
AA3 9  10 O VAL C 141 ? O VAL C 141 N ARG C 128 ? N ARG C 128 
AA3 10 11 O ILE C 129 ? O ILE C 129 N GLY A 127 ? N GLY A 127 
AA3 11 12 N ARG A 128 ? N ARG A 128 O VAL A 141 ? O VAL A 141 
AA3 12 13 N ARG A 140 ? N ARG A 140 O ILE A 478 ? O ILE A 478 
AA3 13 14 N SER A 479 ? N SER A 479 O VAL D 439 ? O VAL D 439 
AA3 14 15 O HIS D 438 ? O HIS D 438 N VAL D 417 ? N VAL D 417 
AA3 15 16 O ALA D 416 ? O ALA D 416 N VAL D 265 ? N VAL D 265 
AA3 16 17 N VAL D 266 ? N VAL D 266 O ILE D 298 ? O ILE D 298 
AA3 17 18 N ILE D 297 ? N ILE D 297 O LEU D 394 ? O LEU D 394 
AA3 18 19 O LEU D 393 ? O LEU D 393 N VAL D 375 ? N VAL D 375 
AA3 19 20 O GLY D 373 ? O GLY D 373 N LYS D 355 ? N LYS D 355 
AA4 1  2  O SER A 207 ? O SER A 207 N VAL A 178 ? N VAL A 178 
AA4 2  3  O ALA A 175 ? O ALA A 175 N VAL A 149 ? N VAL A 149 
AA4 3  4  N ILE A 152 ? N ILE A 152 O THR A 230 ? O THR A 230 
AA4 4  5  N VAL A 229 ? N VAL A 229 O ALA A 255 ? O ALA A 255 
AA5 1  2  N LYS A 355 ? N LYS A 355 O GLY A 373 ? O GLY A 373 
AA5 2  3  N VAL A 375 ? N VAL A 375 O LEU A 393 ? O LEU A 393 
AA5 3  4  O LEU A 394 ? O LEU A 394 N ILE A 297 ? N ILE A 297 
AA5 4  5  O ILE A 298 ? O ILE A 298 N PHE A 264 ? N PHE A 264 
AA5 5  6  N VAL A 265 ? N VAL A 265 O ALA A 416 ? O ALA A 416 
AA5 6  7  N VAL A 417 ? N VAL A 417 O HIS A 438 ? O HIS A 438 
AA5 7  8  N VAL A 439 ? N VAL A 439 O SER D 479 ? O SER D 479 
AA5 8  9  O VAL D 480 ? O VAL D 480 N GLU D 138 ? N GLU D 138 
AA5 9  10 O VAL D 141 ? O VAL D 141 N ARG D 128 ? N ARG D 128 
AA5 10 11 O ILE D 129 ? O ILE D 129 N GLY B 127 ? N GLY B 127 
AA5 11 12 N ARG B 128 ? N ARG B 128 O VAL B 141 ? O VAL B 141 
AA5 12 13 N GLU B 138 ? N GLU B 138 O VAL B 480 ? O VAL B 480 
AA5 13 14 N TRP B 477 ? N TRP B 477 O THR C 437 ? O THR C 437 
AA5 14 15 O HIS C 438 ? O HIS C 438 N VAL C 417 ? N VAL C 417 
AA5 15 16 O ALA C 416 ? O ALA C 416 N VAL C 265 ? N VAL C 265 
AA5 16 17 N VAL C 266 ? N VAL C 266 O ILE C 298 ? O ILE C 298 
AA5 17 18 N ILE C 297 ? N ILE C 297 O LEU C 394 ? O LEU C 394 
AA5 18 19 O LEU C 393 ? O LEU C 393 N PHE C 372 ? N PHE C 372 
AA5 19 20 O VAL C 371 ? O VAL C 371 N TYR C 358 ? N TYR C 358 
AA6 1  2  N ASP A 363 ? N ASP A 363 O LEU A 366 ? O LEU A 366 
AA7 1  2  N GLN B 12  ? N GLN B 12  O ARG B 19  ? O ARG B 19  
AA8 1  2  N VAL B 29  ? N VAL B 29  O LEU B 38  ? O LEU B 38  
AA9 1  2  O SER B 207 ? O SER B 207 N VAL B 178 ? N VAL B 178 
AA9 2  3  O ALA B 175 ? O ALA B 175 N VAL B 149 ? N VAL B 149 
AA9 3  4  N GLY B 150 ? N GLY B 150 O LEU B 228 ? O LEU B 228 
AA9 4  5  N VAL B 229 ? N VAL B 229 O ALA B 255 ? O ALA B 255 
AB1 1  2  N ASP B 363 ? N ASP B 363 O LEU B 366 ? O LEU B 366 
AB2 1  2  N LEU C 14  ? N LEU C 14  O GLU C 17  ? O GLU C 17  
AB3 1  2  N LEU C 27  ? N LEU C 27  O ILE C 41  ? O ILE C 41  
AB4 1  2  O SER C 207 ? O SER C 207 N VAL C 178 ? N VAL C 178 
AB4 2  3  O ALA C 175 ? O ALA C 175 N VAL C 149 ? N VAL C 149 
AB4 3  4  N GLY C 150 ? N GLY C 150 O LEU C 228 ? O LEU C 228 
AB4 4  5  N PHE C 231 ? N PHE C 231 O GLU C 257 ? O GLU C 257 
AB5 1  2  N ASP C 363 ? N ASP C 363 O LEU C 366 ? O LEU C 366 
AB6 1  2  N LEU D 14  ? N LEU D 14  O GLU D 17  ? O GLU D 17  
AB7 1  2  N LEU D 27  ? N LEU D 27  O ILE D 41  ? O ILE D 41  
AB8 1  2  O SER D 207 ? O SER D 207 N VAL D 178 ? N VAL D 178 
AB8 2  3  O LYS D 179 ? O LYS D 179 N VAL D 151 ? N VAL D 151 
AB8 3  4  N ILE D 152 ? N ILE D 152 O THR D 230 ? O THR D 230 
AB8 4  5  N VAL D 229 ? N VAL D 229 O ALA D 255 ? O ALA D 255 
AB9 1  2  N ASP D 363 ? N ASP D 363 O LEU D 366 ? O LEU D 366 
# 
_pdbx_entry_details.entry_id                   8ZCX 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_ligand_of_interest     ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 ARG A 19  ? ? -170.55 -179.12 
2  1 LEU A 285 ? ? -95.66  36.05   
3  1 PHE A 387 ? ? -119.66 53.37   
4  1 ARG A 462 ? ? 48.85   -142.33 
5  1 PHE A 463 ? ? 44.80   -113.99 
6  1 ASN A 464 ? ? 60.57   162.95  
7  1 PHE B 33  ? ? -70.14  -72.61  
8  1 MET B 292 ? ? -90.78  49.99   
9  1 PHE B 387 ? ? -118.10 59.54   
10 1 ARG B 462 ? ? 46.42   -143.70 
11 1 PHE B 463 ? ? 45.98   -119.15 
12 1 ASN B 464 ? ? 65.60   158.20  
13 1 CYS C 187 ? ? -67.20  4.87    
14 1 LEU C 285 ? ? 93.16   -11.28  
15 1 HIS C 286 ? ? -139.36 -70.19  
16 1 GLN C 287 ? ? 32.81   -115.28 
17 1 PHE C 387 ? ? -106.09 73.45   
18 1 GLU C 410 ? ? 67.93   -73.83  
19 1 ARG C 462 ? ? 57.54   -119.66 
20 1 HIS D 286 ? ? 81.81   -177.69 
21 1 PHE D 387 ? ? -113.87 69.47   
22 1 GLU D 410 ? ? 68.28   -60.77  
23 1 SER D 419 ? ? -171.17 137.22  
24 1 ARG D 462 ? ? 61.95   -123.54 
# 
loop_
_pdbx_distant_solvent_atoms.id 
_pdbx_distant_solvent_atoms.PDB_model_num 
_pdbx_distant_solvent_atoms.auth_atom_id 
_pdbx_distant_solvent_atoms.label_alt_id 
_pdbx_distant_solvent_atoms.auth_asym_id 
_pdbx_distant_solvent_atoms.auth_comp_id 
_pdbx_distant_solvent_atoms.auth_seq_id 
_pdbx_distant_solvent_atoms.PDB_ins_code 
_pdbx_distant_solvent_atoms.neighbor_macromolecule_distance 
_pdbx_distant_solvent_atoms.neighbor_ligand_distance 
1 1 O ? C HOH 551 ? 7.16 . 
2 1 O ? C HOH 552 ? 7.26 . 
3 1 O ? C HOH 553 ? 8.93 . 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A MET 1   ? A MET 1   
2   1 Y 1 A SER 2   ? A SER 2   
3   1 Y 1 A ASP 3   ? A ASP 3   
4   1 Y 1 A GLN 287 ? A GLN 287 
5   1 Y 1 A GLY 288 ? A GLY 288 
6   1 Y 1 A GLN 289 ? A GLN 289 
7   1 Y 1 A ILE 290 ? A ILE 290 
8   1 Y 1 A CYS 291 ? A CYS 291 
9   1 Y 1 A MET 292 ? A MET 292 
10  1 Y 1 A ALA 293 ? A ALA 293 
11  1 Y 1 A GLU 410 ? A GLU 410 
12  1 Y 1 A TYR 411 ? A TYR 411 
13  1 Y 1 A GLY 412 ? A GLY 412 
14  1 Y 1 A ILE 442 ? A ILE 442 
15  1 Y 1 A PRO 443 ? A PRO 443 
16  1 Y 1 A VAL 444 ? A VAL 444 
17  1 Y 1 A ASN 445 ? A ASN 445 
18  1 Y 1 A ASP 446 ? A ASP 446 
19  1 Y 1 A GLU 447 ? A GLU 447 
20  1 Y 1 A ALA 448 ? A ALA 448 
21  1 Y 1 A ASN 449 ? A ASN 449 
22  1 Y 1 A ALA 450 ? A ALA 450 
23  1 Y 1 A PRO 451 ? A PRO 451 
24  1 Y 1 A PHE 452 ? A PHE 452 
25  1 Y 1 A GLY 453 ? A GLY 453 
26  1 Y 1 A GLY 454 ? A GLY 454 
27  1 Y 1 A GLU 455 ? A GLU 455 
28  1 Y 1 A LYS 456 ? A LYS 456 
29  1 Y 1 A ASN 457 ? A ASN 457 
30  1 Y 1 A SER 458 ? A SER 458 
31  1 Y 1 A GLY 459 ? A GLY 459 
32  1 Y 1 A LEU 460 ? A LEU 460 
33  1 Y 1 A ALA 483 ? A ALA 483 
34  1 Y 1 A PRO 484 ? A PRO 484 
35  1 Y 1 A ARG 485 ? A ARG 485 
36  1 Y 1 A GLN 486 ? A GLN 486 
37  1 Y 1 A TYR 487 ? A TYR 487 
38  1 Y 1 A PRO 488 ? A PRO 488 
39  1 Y 1 A PHE 489 ? A PHE 489 
40  1 Y 1 B MET 1   ? B MET 1   
41  1 Y 1 B SER 2   ? B SER 2   
42  1 Y 1 B LEU 285 ? B LEU 285 
43  1 Y 1 B HIS 286 ? B HIS 286 
44  1 Y 1 B GLN 287 ? B GLN 287 
45  1 Y 1 B GLY 288 ? B GLY 288 
46  1 Y 1 B GLN 289 ? B GLN 289 
47  1 Y 1 B VAL 444 ? B VAL 444 
48  1 Y 1 B ASN 445 ? B ASN 445 
49  1 Y 1 B ASP 446 ? B ASP 446 
50  1 Y 1 B GLU 447 ? B GLU 447 
51  1 Y 1 B ALA 448 ? B ALA 448 
52  1 Y 1 B ASN 449 ? B ASN 449 
53  1 Y 1 B ALA 450 ? B ALA 450 
54  1 Y 1 B PRO 451 ? B PRO 451 
55  1 Y 1 B PHE 452 ? B PHE 452 
56  1 Y 1 B GLY 453 ? B GLY 453 
57  1 Y 1 B GLY 454 ? B GLY 454 
58  1 Y 1 B GLU 455 ? B GLU 455 
59  1 Y 1 B LYS 456 ? B LYS 456 
60  1 Y 1 B ASN 457 ? B ASN 457 
61  1 Y 1 B SER 458 ? B SER 458 
62  1 Y 1 B PHE 489 ? B PHE 489 
63  1 Y 1 C MET 1   ? C MET 1   
64  1 Y 1 C GLN 289 ? C GLN 289 
65  1 Y 1 C ILE 290 ? C ILE 290 
66  1 Y 1 C CYS 291 ? C CYS 291 
67  1 Y 1 C MET 292 ? C MET 292 
68  1 Y 1 C ALA 293 ? C ALA 293 
69  1 Y 1 C GLU 447 ? C GLU 447 
70  1 Y 1 C ALA 448 ? C ALA 448 
71  1 Y 1 C ASN 449 ? C ASN 449 
72  1 Y 1 C ALA 450 ? C ALA 450 
73  1 Y 1 C PRO 451 ? C PRO 451 
74  1 Y 1 C PHE 452 ? C PHE 452 
75  1 Y 1 C GLY 453 ? C GLY 453 
76  1 Y 1 C GLY 454 ? C GLY 454 
77  1 Y 1 C GLU 455 ? C GLU 455 
78  1 Y 1 C LYS 456 ? C LYS 456 
79  1 Y 1 C ASN 457 ? C ASN 457 
80  1 Y 1 C ALA 483 ? C ALA 483 
81  1 Y 1 C PRO 484 ? C PRO 484 
82  1 Y 1 C ARG 485 ? C ARG 485 
83  1 Y 1 C GLN 486 ? C GLN 486 
84  1 Y 1 C TYR 487 ? C TYR 487 
85  1 Y 1 C PRO 488 ? C PRO 488 
86  1 Y 1 C PHE 489 ? C PHE 489 
87  1 Y 1 D MET 1   ? D MET 1   
88  1 Y 1 D SER 2   ? D SER 2   
89  1 Y 1 D GLY 288 ? D GLY 288 
90  1 Y 1 D GLN 289 ? D GLN 289 
91  1 Y 1 D ILE 290 ? D ILE 290 
92  1 Y 1 D CYS 291 ? D CYS 291 
93  1 Y 1 D MET 292 ? D MET 292 
94  1 Y 1 D VAL 444 ? D VAL 444 
95  1 Y 1 D ASN 445 ? D ASN 445 
96  1 Y 1 D ASP 446 ? D ASP 446 
97  1 Y 1 D GLU 447 ? D GLU 447 
98  1 Y 1 D ALA 448 ? D ALA 448 
99  1 Y 1 D ASN 449 ? D ASN 449 
100 1 Y 1 D ALA 450 ? D ALA 450 
101 1 Y 1 D PRO 451 ? D PRO 451 
102 1 Y 1 D PHE 452 ? D PHE 452 
103 1 Y 1 D GLY 453 ? D GLY 453 
104 1 Y 1 D GLY 454 ? D GLY 454 
105 1 Y 1 D GLU 455 ? D GLU 455 
106 1 Y 1 D LYS 456 ? D LYS 456 
107 1 Y 1 D ASN 457 ? D ASN 457 
108 1 Y 1 D SER 458 ? D SER 458 
109 1 Y 1 D ALA 483 ? D ALA 483 
110 1 Y 1 D PRO 484 ? D PRO 484 
111 1 Y 1 D ARG 485 ? D ARG 485 
112 1 Y 1 D GLN 486 ? D GLN 486 
113 1 Y 1 D TYR 487 ? D TYR 487 
114 1 Y 1 D PRO 488 ? D PRO 488 
115 1 Y 1 D PHE 489 ? D PHE 489 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
HOH O    O N N 158 
HOH H1   H N N 159 
HOH H2   H N N 160 
ILE N    N N N 161 
ILE CA   C N S 162 
ILE C    C N N 163 
ILE O    O N N 164 
ILE CB   C N S 165 
ILE CG1  C N N 166 
ILE CG2  C N N 167 
ILE CD1  C N N 168 
ILE OXT  O N N 169 
ILE H    H N N 170 
ILE H2   H N N 171 
ILE HA   H N N 172 
ILE HB   H N N 173 
ILE HG12 H N N 174 
ILE HG13 H N N 175 
ILE HG21 H N N 176 
ILE HG22 H N N 177 
ILE HG23 H N N 178 
ILE HD11 H N N 179 
ILE HD12 H N N 180 
ILE HD13 H N N 181 
ILE HXT  H N N 182 
LEU N    N N N 183 
LEU CA   C N S 184 
LEU C    C N N 185 
LEU O    O N N 186 
LEU CB   C N N 187 
LEU CG   C N N 188 
LEU CD1  C N N 189 
LEU CD2  C N N 190 
LEU OXT  O N N 191 
LEU H    H N N 192 
LEU H2   H N N 193 
LEU HA   H N N 194 
LEU HB2  H N N 195 
LEU HB3  H N N 196 
LEU HG   H N N 197 
LEU HD11 H N N 198 
LEU HD12 H N N 199 
LEU HD13 H N N 200 
LEU HD21 H N N 201 
LEU HD22 H N N 202 
LEU HD23 H N N 203 
LEU HXT  H N N 204 
LYS N    N N N 205 
LYS CA   C N S 206 
LYS C    C N N 207 
LYS O    O N N 208 
LYS CB   C N N 209 
LYS CG   C N N 210 
LYS CD   C N N 211 
LYS CE   C N N 212 
LYS NZ   N N N 213 
LYS OXT  O N N 214 
LYS H    H N N 215 
LYS H2   H N N 216 
LYS HA   H N N 217 
LYS HB2  H N N 218 
LYS HB3  H N N 219 
LYS HG2  H N N 220 
LYS HG3  H N N 221 
LYS HD2  H N N 222 
LYS HD3  H N N 223 
LYS HE2  H N N 224 
LYS HE3  H N N 225 
LYS HZ1  H N N 226 
LYS HZ2  H N N 227 
LYS HZ3  H N N 228 
LYS HXT  H N N 229 
MET N    N N N 230 
MET CA   C N S 231 
MET C    C N N 232 
MET O    O N N 233 
MET CB   C N N 234 
MET CG   C N N 235 
MET SD   S N N 236 
MET CE   C N N 237 
MET OXT  O N N 238 
MET H    H N N 239 
MET H2   H N N 240 
MET HA   H N N 241 
MET HB2  H N N 242 
MET HB3  H N N 243 
MET HG2  H N N 244 
MET HG3  H N N 245 
MET HE1  H N N 246 
MET HE2  H N N 247 
MET HE3  H N N 248 
MET HXT  H N N 249 
PHE N    N N N 250 
PHE CA   C N S 251 
PHE C    C N N 252 
PHE O    O N N 253 
PHE CB   C N N 254 
PHE CG   C Y N 255 
PHE CD1  C Y N 256 
PHE CD2  C Y N 257 
PHE CE1  C Y N 258 
PHE CE2  C Y N 259 
PHE CZ   C Y N 260 
PHE OXT  O N N 261 
PHE H    H N N 262 
PHE H2   H N N 263 
PHE HA   H N N 264 
PHE HB2  H N N 265 
PHE HB3  H N N 266 
PHE HD1  H N N 267 
PHE HD2  H N N 268 
PHE HE1  H N N 269 
PHE HE2  H N N 270 
PHE HZ   H N N 271 
PHE HXT  H N N 272 
PRO N    N N N 273 
PRO CA   C N S 274 
PRO C    C N N 275 
PRO O    O N N 276 
PRO CB   C N N 277 
PRO CG   C N N 278 
PRO CD   C N N 279 
PRO OXT  O N N 280 
PRO H    H N N 281 
PRO HA   H N N 282 
PRO HB2  H N N 283 
PRO HB3  H N N 284 
PRO HG2  H N N 285 
PRO HG3  H N N 286 
PRO HD2  H N N 287 
PRO HD3  H N N 288 
PRO HXT  H N N 289 
SER N    N N N 290 
SER CA   C N S 291 
SER C    C N N 292 
SER O    O N N 293 
SER CB   C N N 294 
SER OG   O N N 295 
SER OXT  O N N 296 
SER H    H N N 297 
SER H2   H N N 298 
SER HA   H N N 299 
SER HB2  H N N 300 
SER HB3  H N N 301 
SER HG   H N N 302 
SER HXT  H N N 303 
THR N    N N N 304 
THR CA   C N S 305 
THR C    C N N 306 
THR O    O N N 307 
THR CB   C N R 308 
THR OG1  O N N 309 
THR CG2  C N N 310 
THR OXT  O N N 311 
THR H    H N N 312 
THR H2   H N N 313 
THR HA   H N N 314 
THR HB   H N N 315 
THR HG1  H N N 316 
THR HG21 H N N 317 
THR HG22 H N N 318 
THR HG23 H N N 319 
THR HXT  H N N 320 
TRP N    N N N 321 
TRP CA   C N S 322 
TRP C    C N N 323 
TRP O    O N N 324 
TRP CB   C N N 325 
TRP CG   C Y N 326 
TRP CD1  C Y N 327 
TRP CD2  C Y N 328 
TRP NE1  N Y N 329 
TRP CE2  C Y N 330 
TRP CE3  C Y N 331 
TRP CZ2  C Y N 332 
TRP CZ3  C Y N 333 
TRP CH2  C Y N 334 
TRP OXT  O N N 335 
TRP H    H N N 336 
TRP H2   H N N 337 
TRP HA   H N N 338 
TRP HB2  H N N 339 
TRP HB3  H N N 340 
TRP HD1  H N N 341 
TRP HE1  H N N 342 
TRP HE3  H N N 343 
TRP HZ2  H N N 344 
TRP HZ3  H N N 345 
TRP HH2  H N N 346 
TRP HXT  H N N 347 
TYR N    N N N 348 
TYR CA   C N S 349 
TYR C    C N N 350 
TYR O    O N N 351 
TYR CB   C N N 352 
TYR CG   C Y N 353 
TYR CD1  C Y N 354 
TYR CD2  C Y N 355 
TYR CE1  C Y N 356 
TYR CE2  C Y N 357 
TYR CZ   C Y N 358 
TYR OH   O N N 359 
TYR OXT  O N N 360 
TYR H    H N N 361 
TYR H2   H N N 362 
TYR HA   H N N 363 
TYR HB2  H N N 364 
TYR HB3  H N N 365 
TYR HD1  H N N 366 
TYR HD2  H N N 367 
TYR HE1  H N N 368 
TYR HE2  H N N 369 
TYR HH   H N N 370 
TYR HXT  H N N 371 
VAL N    N N N 372 
VAL CA   C N S 373 
VAL C    C N N 374 
VAL O    O N N 375 
VAL CB   C N N 376 
VAL CG1  C N N 377 
VAL CG2  C N N 378 
VAL OXT  O N N 379 
VAL H    H N N 380 
VAL H2   H N N 381 
VAL HA   H N N 382 
VAL HB   H N N 383 
VAL HG11 H N N 384 
VAL HG12 H N N 385 
VAL HG13 H N N 386 
VAL HG21 H N N 387 
VAL HG22 H N N 388 
VAL HG23 H N N 389 
VAL HXT  H N N 390 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
HOH O   H1   sing N N 150 
HOH O   H2   sing N N 151 
ILE N   CA   sing N N 152 
ILE N   H    sing N N 153 
ILE N   H2   sing N N 154 
ILE CA  C    sing N N 155 
ILE CA  CB   sing N N 156 
ILE CA  HA   sing N N 157 
ILE C   O    doub N N 158 
ILE C   OXT  sing N N 159 
ILE CB  CG1  sing N N 160 
ILE CB  CG2  sing N N 161 
ILE CB  HB   sing N N 162 
ILE CG1 CD1  sing N N 163 
ILE CG1 HG12 sing N N 164 
ILE CG1 HG13 sing N N 165 
ILE CG2 HG21 sing N N 166 
ILE CG2 HG22 sing N N 167 
ILE CG2 HG23 sing N N 168 
ILE CD1 HD11 sing N N 169 
ILE CD1 HD12 sing N N 170 
ILE CD1 HD13 sing N N 171 
ILE OXT HXT  sing N N 172 
LEU N   CA   sing N N 173 
LEU N   H    sing N N 174 
LEU N   H2   sing N N 175 
LEU CA  C    sing N N 176 
LEU CA  CB   sing N N 177 
LEU CA  HA   sing N N 178 
LEU C   O    doub N N 179 
LEU C   OXT  sing N N 180 
LEU CB  CG   sing N N 181 
LEU CB  HB2  sing N N 182 
LEU CB  HB3  sing N N 183 
LEU CG  CD1  sing N N 184 
LEU CG  CD2  sing N N 185 
LEU CG  HG   sing N N 186 
LEU CD1 HD11 sing N N 187 
LEU CD1 HD12 sing N N 188 
LEU CD1 HD13 sing N N 189 
LEU CD2 HD21 sing N N 190 
LEU CD2 HD22 sing N N 191 
LEU CD2 HD23 sing N N 192 
LEU OXT HXT  sing N N 193 
LYS N   CA   sing N N 194 
LYS N   H    sing N N 195 
LYS N   H2   sing N N 196 
LYS CA  C    sing N N 197 
LYS CA  CB   sing N N 198 
LYS CA  HA   sing N N 199 
LYS C   O    doub N N 200 
LYS C   OXT  sing N N 201 
LYS CB  CG   sing N N 202 
LYS CB  HB2  sing N N 203 
LYS CB  HB3  sing N N 204 
LYS CG  CD   sing N N 205 
LYS CG  HG2  sing N N 206 
LYS CG  HG3  sing N N 207 
LYS CD  CE   sing N N 208 
LYS CD  HD2  sing N N 209 
LYS CD  HD3  sing N N 210 
LYS CE  NZ   sing N N 211 
LYS CE  HE2  sing N N 212 
LYS CE  HE3  sing N N 213 
LYS NZ  HZ1  sing N N 214 
LYS NZ  HZ2  sing N N 215 
LYS NZ  HZ3  sing N N 216 
LYS OXT HXT  sing N N 217 
MET N   CA   sing N N 218 
MET N   H    sing N N 219 
MET N   H2   sing N N 220 
MET CA  C    sing N N 221 
MET CA  CB   sing N N 222 
MET CA  HA   sing N N 223 
MET C   O    doub N N 224 
MET C   OXT  sing N N 225 
MET CB  CG   sing N N 226 
MET CB  HB2  sing N N 227 
MET CB  HB3  sing N N 228 
MET CG  SD   sing N N 229 
MET CG  HG2  sing N N 230 
MET CG  HG3  sing N N 231 
MET SD  CE   sing N N 232 
MET CE  HE1  sing N N 233 
MET CE  HE2  sing N N 234 
MET CE  HE3  sing N N 235 
MET OXT HXT  sing N N 236 
PHE N   CA   sing N N 237 
PHE N   H    sing N N 238 
PHE N   H2   sing N N 239 
PHE CA  C    sing N N 240 
PHE CA  CB   sing N N 241 
PHE CA  HA   sing N N 242 
PHE C   O    doub N N 243 
PHE C   OXT  sing N N 244 
PHE CB  CG   sing N N 245 
PHE CB  HB2  sing N N 246 
PHE CB  HB3  sing N N 247 
PHE CG  CD1  doub Y N 248 
PHE CG  CD2  sing Y N 249 
PHE CD1 CE1  sing Y N 250 
PHE CD1 HD1  sing N N 251 
PHE CD2 CE2  doub Y N 252 
PHE CD2 HD2  sing N N 253 
PHE CE1 CZ   doub Y N 254 
PHE CE1 HE1  sing N N 255 
PHE CE2 CZ   sing Y N 256 
PHE CE2 HE2  sing N N 257 
PHE CZ  HZ   sing N N 258 
PHE OXT HXT  sing N N 259 
PRO N   CA   sing N N 260 
PRO N   CD   sing N N 261 
PRO N   H    sing N N 262 
PRO CA  C    sing N N 263 
PRO CA  CB   sing N N 264 
PRO CA  HA   sing N N 265 
PRO C   O    doub N N 266 
PRO C   OXT  sing N N 267 
PRO CB  CG   sing N N 268 
PRO CB  HB2  sing N N 269 
PRO CB  HB3  sing N N 270 
PRO CG  CD   sing N N 271 
PRO CG  HG2  sing N N 272 
PRO CG  HG3  sing N N 273 
PRO CD  HD2  sing N N 274 
PRO CD  HD3  sing N N 275 
PRO OXT HXT  sing N N 276 
SER N   CA   sing N N 277 
SER N   H    sing N N 278 
SER N   H2   sing N N 279 
SER CA  C    sing N N 280 
SER CA  CB   sing N N 281 
SER CA  HA   sing N N 282 
SER C   O    doub N N 283 
SER C   OXT  sing N N 284 
SER CB  OG   sing N N 285 
SER CB  HB2  sing N N 286 
SER CB  HB3  sing N N 287 
SER OG  HG   sing N N 288 
SER OXT HXT  sing N N 289 
THR N   CA   sing N N 290 
THR N   H    sing N N 291 
THR N   H2   sing N N 292 
THR CA  C    sing N N 293 
THR CA  CB   sing N N 294 
THR CA  HA   sing N N 295 
THR C   O    doub N N 296 
THR C   OXT  sing N N 297 
THR CB  OG1  sing N N 298 
THR CB  CG2  sing N N 299 
THR CB  HB   sing N N 300 
THR OG1 HG1  sing N N 301 
THR CG2 HG21 sing N N 302 
THR CG2 HG22 sing N N 303 
THR CG2 HG23 sing N N 304 
THR OXT HXT  sing N N 305 
TRP N   CA   sing N N 306 
TRP N   H    sing N N 307 
TRP N   H2   sing N N 308 
TRP CA  C    sing N N 309 
TRP CA  CB   sing N N 310 
TRP CA  HA   sing N N 311 
TRP C   O    doub N N 312 
TRP C   OXT  sing N N 313 
TRP CB  CG   sing N N 314 
TRP CB  HB2  sing N N 315 
TRP CB  HB3  sing N N 316 
TRP CG  CD1  doub Y N 317 
TRP CG  CD2  sing Y N 318 
TRP CD1 NE1  sing Y N 319 
TRP CD1 HD1  sing N N 320 
TRP CD2 CE2  doub Y N 321 
TRP CD2 CE3  sing Y N 322 
TRP NE1 CE2  sing Y N 323 
TRP NE1 HE1  sing N N 324 
TRP CE2 CZ2  sing Y N 325 
TRP CE3 CZ3  doub Y N 326 
TRP CE3 HE3  sing N N 327 
TRP CZ2 CH2  doub Y N 328 
TRP CZ2 HZ2  sing N N 329 
TRP CZ3 CH2  sing Y N 330 
TRP CZ3 HZ3  sing N N 331 
TRP CH2 HH2  sing N N 332 
TRP OXT HXT  sing N N 333 
TYR N   CA   sing N N 334 
TYR N   H    sing N N 335 
TYR N   H2   sing N N 336 
TYR CA  C    sing N N 337 
TYR CA  CB   sing N N 338 
TYR CA  HA   sing N N 339 
TYR C   O    doub N N 340 
TYR C   OXT  sing N N 341 
TYR CB  CG   sing N N 342 
TYR CB  HB2  sing N N 343 
TYR CB  HB3  sing N N 344 
TYR CG  CD1  doub Y N 345 
TYR CG  CD2  sing Y N 346 
TYR CD1 CE1  sing Y N 347 
TYR CD1 HD1  sing N N 348 
TYR CD2 CE2  doub Y N 349 
TYR CD2 HD2  sing N N 350 
TYR CE1 CZ   doub Y N 351 
TYR CE1 HE1  sing N N 352 
TYR CE2 CZ   sing Y N 353 
TYR CE2 HE2  sing N N 354 
TYR CZ  OH   sing N N 355 
TYR OH  HH   sing N N 356 
TYR OXT HXT  sing N N 357 
VAL N   CA   sing N N 358 
VAL N   H    sing N N 359 
VAL N   H2   sing N N 360 
VAL CA  C    sing N N 361 
VAL CA  CB   sing N N 362 
VAL CA  HA   sing N N 363 
VAL C   O    doub N N 364 
VAL C   OXT  sing N N 365 
VAL CB  CG1  sing N N 366 
VAL CB  CG2  sing N N 367 
VAL CB  HB   sing N N 368 
VAL CG1 HG11 sing N N 369 
VAL CG1 HG12 sing N N 370 
VAL CG1 HG13 sing N N 371 
VAL CG2 HG21 sing N N 372 
VAL CG2 HG22 sing N N 373 
VAL CG2 HG23 sing N N 374 
VAL OXT HXT  sing N N 375 
# 
_pdbx_audit_support.funding_organization   'Ministry of Science and Technology (MoST, China)' 
_pdbx_audit_support.country                China 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'in silico model' 
_pdbx_initial_refinement_model.source_name      AlphaFold 
_pdbx_initial_refinement_model.accession_code   ? 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    8ZCX 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.009740 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   -0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.006815 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   -0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.006688 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1     N N   . SER A 1 4   ? 7.181   35.096  -18.509 1.00 114.47 ? 4   SER A N   1 
ATOM   2     C CA  . SER A 1 4   ? 6.253   36.081  -18.071 1.00 111.73 ? 4   SER A CA  1 
ATOM   3     C C   . SER A 1 4   ? 5.224   35.534  -17.054 1.00 94.70  ? 4   SER A C   1 
ATOM   4     O O   . SER A 1 4   ? 4.659   34.437  -17.212 1.00 90.99  ? 4   SER A O   1 
ATOM   5     C CB  . SER A 1 4   ? 5.550   36.630  -19.266 1.00 115.98 ? 4   SER A CB  1 
ATOM   6     O OG  . SER A 1 4   ? 4.384   35.862  -19.567 1.00 113.66 ? 4   SER A OG  1 
ATOM   7     N N   . ARG A 1 5   ? 4.873   36.408  -16.113 1.00 81.73  ? 5   ARG A N   1 
ATOM   8     C CA  . ARG A 1 5   ? 3.732   36.220  -15.254 1.00 76.94  ? 5   ARG A CA  1 
ATOM   9     C C   . ARG A 1 5   ? 2.457   36.314  -16.076 1.00 76.97  ? 5   ARG A C   1 
ATOM   10    O O   . ARG A 1 5   ? 2.427   36.955  -17.124 1.00 80.44  ? 5   ARG A O   1 
ATOM   11    C CB  . ARG A 1 5   ? 3.748   37.267  -14.133 1.00 78.26  ? 5   ARG A CB  1 
ATOM   12    C CG  . ARG A 1 5   ? 4.568   36.829  -12.927 1.00 82.77  ? 5   ARG A CG  1 
ATOM   13    C CD  . ARG A 1 5   ? 4.367   37.727  -11.723 1.00 85.10  ? 5   ARG A CD  1 
ATOM   14    N NE  . ARG A 1 5   ? 5.370   37.462  -10.681 1.00 83.64  ? 5   ARG A NE  1 
ATOM   15    C CZ  . ARG A 1 5   ? 5.273   37.842  -9.401  1.00 82.53  ? 5   ARG A CZ  1 
ATOM   16    N NH1 . ARG A 1 5   ? 4.285   38.633  -9.010  1.00 84.67  ? 5   ARG A NH1 1 
ATOM   17    N NH2 . ARG A 1 5   ? 6.168   37.420  -8.516  1.00 82.52  ? 5   ARG A NH2 1 
ATOM   18    N N   . TYR A 1 6   ? 1.409   35.652  -15.589 1.00 77.35  ? 6   TYR A N   1 
ATOM   19    C CA  . TYR A 1 6   ? 0.119   35.670  -16.252 1.00 76.38  ? 6   TYR A CA  1 
ATOM   20    C C   . TYR A 1 6   ? -0.343  37.112  -16.400 1.00 76.68  ? 6   TYR A C   1 
ATOM   21    O O   . TYR A 1 6   ? -0.218  37.896  -15.459 1.00 83.64  ? 6   TYR A O   1 
ATOM   22    C CB  . TYR A 1 6   ? -0.903  34.850  -15.459 1.00 78.04  ? 6   TYR A CB  1 
ATOM   23    C CG  . TYR A 1 6   ? -0.719  33.345  -15.545 1.00 77.33  ? 6   TYR A CG  1 
ATOM   24    C CD1 . TYR A 1 6   ? -0.717  32.558  -14.401 1.00 73.78  ? 6   TYR A CD1 1 
ATOM   25    C CD2 . TYR A 1 6   ? -0.572  32.711  -16.772 1.00 80.17  ? 6   TYR A CD2 1 
ATOM   26    C CE1 . TYR A 1 6   ? -0.543  31.190  -14.473 1.00 70.43  ? 6   TYR A CE1 1 
ATOM   27    C CE2 . TYR A 1 6   ? -0.389  31.344  -16.857 1.00 77.37  ? 6   TYR A CE2 1 
ATOM   28    C CZ  . TYR A 1 6   ? -0.373  30.582  -15.703 1.00 74.28  ? 6   TYR A CZ  1 
ATOM   29    O OH  . TYR A 1 6   ? -0.201  29.243  -15.785 1.00 65.77  ? 6   TYR A OH  1 
ATOM   30    N N   . THR A 1 7   ? -0.910  37.445  -17.577 1.00 66.86  ? 7   THR A N   1 
ATOM   31    C CA  . THR A 1 7   ? -1.480  38.780  -17.802 1.00 78.87  ? 7   THR A CA  1 
ATOM   32    C C   . THR A 1 7   ? -2.929  38.653  -18.272 1.00 80.32  ? 7   THR A C   1 
ATOM   33    O O   . THR A 1 7   ? -3.404  37.554  -18.547 1.00 80.06  ? 7   THR A O   1 
ATOM   34    C CB  . THR A 1 7   ? -0.626  39.564  -18.809 1.00 78.65  ? 7   THR A CB  1 
ATOM   35    O OG1 . THR A 1 7   ? -0.429  38.706  -19.937 1.00 89.20  ? 7   THR A OG1 1 
ATOM   36    C CG2 . THR A 1 7   ? 0.710   39.997  -18.221 1.00 71.53  ? 7   THR A CG2 1 
ATOM   37    N N   . ASP A 1 8   ? -3.623  39.806  -18.338 1.00 85.66  ? 8   ASP A N   1 
ATOM   38    C CA  . ASP A 1 8   ? -5.011  39.871  -18.775 1.00 89.58  ? 8   ASP A CA  1 
ATOM   39    C C   . ASP A 1 8   ? -5.859  38.956  -17.897 1.00 86.62  ? 8   ASP A C   1 
ATOM   40    O O   . ASP A 1 8   ? -6.742  38.257  -18.387 1.00 79.11  ? 8   ASP A O   1 
ATOM   41    C CB  . ASP A 1 8   ? -5.152  39.500  -20.242 1.00 101.53 ? 8   ASP A CB  1 
ATOM   42    C CG  . ASP A 1 8   ? -4.130  40.127  -21.167 1.00 103.14 ? 8   ASP A CG  1 
ATOM   43    O OD1 . ASP A 1 8   ? -4.351  41.275  -21.578 1.00 91.88  ? 8   ASP A OD1 1 
ATOM   44    O OD2 . ASP A 1 8   ? -3.096  39.476  -21.419 1.00 110.36 ? 8   ASP A OD2 1 
ATOM   45    N N   . LEU A 1 9   ? -5.589  38.979  -16.594 1.00 90.63  ? 9   LEU A N   1 
ATOM   46    C CA  . LEU A 1 9   ? -6.234  38.066  -15.661 1.00 92.00  ? 9   LEU A CA  1 
ATOM   47    C C   . LEU A 1 9   ? -7.716  38.430  -15.499 1.00 96.89  ? 9   LEU A C   1 
ATOM   48    O O   . LEU A 1 9   ? -8.481  37.658  -14.924 1.00 102.03 ? 9   LEU A O   1 
ATOM   49    C CB  . LEU A 1 9   ? -5.482  38.088  -14.326 1.00 83.86  ? 9   LEU A CB  1 
ATOM   50    C CG  . LEU A 1 9   ? -4.074  37.483  -14.359 1.00 73.25  ? 9   LEU A CG  1 
ATOM   51    C CD1 . LEU A 1 9   ? -3.425  37.447  -13.011 1.00 70.07  ? 9   LEU A CD1 1 
ATOM   52    C CD2 . LEU A 1 9   ? -4.148  36.101  -14.944 1.00 79.00  ? 9   LEU A CD2 1 
ATOM   53    N N   . GLY A 1 10  ? -8.117  39.596  -16.040 1.00 95.10  ? 10  GLY A N   1 
ATOM   54    C CA  . GLY A 1 10  ? -9.510  40.031  -16.010 1.00 87.50  ? 10  GLY A CA  1 
ATOM   55    C C   . GLY A 1 10  ? -10.403 39.170  -16.911 1.00 79.72  ? 10  GLY A C   1 
ATOM   56    O O   . GLY A 1 10  ? -11.619 39.147  -16.742 1.00 76.95  ? 10  GLY A O   1 
ATOM   57    N N   . LEU A 1 11  ? -9.794  38.484  -17.882 1.00 82.53  ? 11  LEU A N   1 
ATOM   58    C CA  . LEU A 1 11  ? -10.547 37.679  -18.833 1.00 91.10  ? 11  LEU A CA  1 
ATOM   59    C C   . LEU A 1 11  ? -11.138 36.464  -18.114 1.00 91.34  ? 11  LEU A C   1 
ATOM   60    O O   . LEU A 1 11  ? -10.487 35.856  -17.268 1.00 94.32  ? 11  LEU A O   1 
ATOM   61    C CB  . LEU A 1 11  ? -9.649  37.265  -19.997 1.00 96.07  ? 11  LEU A CB  1 
ATOM   62    C CG  . LEU A 1 11  ? -9.249  38.380  -20.972 1.00 93.98  ? 11  LEU A CG  1 
ATOM   63    C CD1 . LEU A 1 11  ? -7.965  38.017  -21.686 1.00 88.83  ? 11  LEU A CD1 1 
ATOM   64    C CD2 . LEU A 1 11  ? -10.363 38.668  -21.989 1.00 97.93  ? 11  LEU A CD2 1 
ATOM   65    N N   . GLN A 1 12  ? -12.385 36.132  -18.463 1.00 93.63  ? 12  GLN A N   1 
ATOM   66    C CA  . GLN A 1 12  ? -13.094 35.017  -17.862 1.00 88.31  ? 12  GLN A CA  1 
ATOM   67    C C   . GLN A 1 12  ? -13.102 33.833  -18.835 1.00 90.26  ? 12  GLN A C   1 
ATOM   68    O O   . GLN A 1 12  ? -13.424 33.996  -20.014 1.00 80.92  ? 12  GLN A O   1 
ATOM   69    C CB  . GLN A 1 12  ? -14.522 35.431  -17.516 1.00 81.77  ? 12  GLN A CB  1 
ATOM   70    C CG  . GLN A 1 12  ? -14.642 36.223  -16.223 1.00 81.08  ? 12  GLN A CG  1 
ATOM   71    C CD  . GLN A 1 12  ? -16.084 36.494  -15.827 1.00 85.15  ? 12  GLN A CD  1 
ATOM   72    O OE1 . GLN A 1 12  ? -16.942 35.596  -15.829 1.00 72.18  ? 12  GLN A OE1 1 
ATOM   73    N NE2 . GLN A 1 12  ? -16.371 37.747  -15.506 1.00 94.92  ? 12  GLN A NE2 1 
ATOM   74    N N   . PRO A 1 13  ? -12.780 32.601  -18.370 1.00 79.63  ? 13  PRO A N   1 
ATOM   75    C CA  . PRO A 1 13  ? -12.922 31.414  -19.208 1.00 78.12  ? 13  PRO A CA  1 
ATOM   76    C C   . PRO A 1 13  ? -14.391 31.001  -19.299 1.00 77.59  ? 13  PRO A C   1 
ATOM   77    O O   . PRO A 1 13  ? -14.945 30.431  -18.357 1.00 68.14  ? 13  PRO A O   1 
ATOM   78    C CB  . PRO A 1 13  ? -12.053 30.374  -18.524 1.00 82.08  ? 13  PRO A CB  1 
ATOM   79    C CG  . PRO A 1 13  ? -12.065 30.794  -17.036 1.00 85.01  ? 13  PRO A CG  1 
ATOM   80    C CD  . PRO A 1 13  ? -12.288 32.301  -17.019 1.00 79.05  ? 13  PRO A CD  1 
ATOM   81    N N   . LEU A 1 14  ? -15.022 31.349  -20.429 1.00 80.55  ? 14  LEU A N   1 
ATOM   82    C CA  . LEU A 1 14  ? -16.456 31.163  -20.613 1.00 82.36  ? 14  LEU A CA  1 
ATOM   83    C C   . LEU A 1 14  ? -16.688 30.339  -21.869 1.00 79.76  ? 14  LEU A C   1 
ATOM   84    O O   . LEU A 1 14  ? -16.390 30.793  -22.965 1.00 79.20  ? 14  LEU A O   1 
ATOM   85    C CB  . LEU A 1 14  ? -17.159 32.521  -20.700 1.00 81.22  ? 14  LEU A CB  1 
ATOM   86    C CG  . LEU A 1 14  ? -17.343 33.265  -19.372 1.00 89.83  ? 14  LEU A CG  1 
ATOM   87    C CD1 . LEU A 1 14  ? -17.530 34.757  -19.580 1.00 92.76  ? 14  LEU A CD1 1 
ATOM   88    C CD2 . LEU A 1 14  ? -18.508 32.702  -18.603 1.00 92.76  ? 14  LEU A CD2 1 
ATOM   89    N N   . ALA A 1 15  ? -17.290 29.159  -21.706 1.00 76.26  ? 15  ALA A N   1 
ATOM   90    C CA  . ALA A 1 15  ? -17.625 28.296  -22.865 1.00 72.69  ? 15  ALA A CA  1 
ATOM   91    C C   . ALA A 1 15  ? -16.390 28.061  -23.733 1.00 75.06  ? 15  ALA A C   1 
ATOM   92    O O   . ALA A 1 15  ? -16.528 28.018  -24.972 1.00 73.13  ? 15  ALA A O   1 
ATOM   93    C CB  . ALA A 1 15  ? -18.764 28.894  -23.660 1.00 74.80  ? 15  ALA A CB  1 
ATOM   94    N N   . GLY A 1 16  ? -15.220 27.927  -23.107 1.00 83.71  ? 16  GLY A N   1 
ATOM   95    C CA  . GLY A 1 16  ? -13.990 27.598  -23.852 1.00 86.01  ? 16  GLY A CA  1 
ATOM   96    C C   . GLY A 1 16  ? -13.347 28.812  -24.488 1.00 82.77  ? 16  GLY A C   1 
ATOM   97    O O   . GLY A 1 16  ? -12.336 28.634  -25.197 1.00 73.64  ? 16  GLY A O   1 
ATOM   98    N N   . GLU A 1 17  ? -13.892 30.004  -24.249 1.00 96.02  ? 17  GLU A N   1 
ATOM   99    C CA  . GLU A 1 17  ? -13.224 31.226  -24.767 1.00 104.07 ? 17  GLU A CA  1 
ATOM   100   C C   . GLU A 1 17  ? -12.903 32.159  -23.592 1.00 100.17 ? 17  GLU A C   1 
ATOM   101   O O   . GLU A 1 17  ? -13.786 32.362  -22.731 1.00 100.56 ? 17  GLU A O   1 
ATOM   102   C CB  . GLU A 1 17  ? -14.054 31.895  -25.867 1.00 116.96 ? 17  GLU A CB  1 
ATOM   103   C CG  . GLU A 1 17  ? -15.312 32.608  -25.382 1.00 129.13 ? 17  GLU A CG  1 
ATOM   104   C CD  . GLU A 1 17  ? -16.608 31.934  -25.791 1.00 133.08 ? 17  GLU A CD  1 
ATOM   105   O OE1 . GLU A 1 17  ? -16.544 30.910  -26.503 1.00 123.48 ? 17  GLU A OE1 1 
ATOM   106   O OE2 . GLU A 1 17  ? -17.681 32.428  -25.387 1.00 147.02 ? 17  GLU A OE2 1 
ATOM   107   N N   . TRP A 1 18  ? -11.666 32.652  -23.522 1.00 95.55  ? 18  TRP A N   1 
ATOM   108   C CA  . TRP A 1 18  ? -11.365 33.664  -22.483 1.00 100.50 ? 18  TRP A CA  1 
ATOM   109   C C   . TRP A 1 18  ? -11.862 34.995  -23.032 1.00 101.69 ? 18  TRP A C   1 
ATOM   110   O O   . TRP A 1 18  ? -11.482 35.328  -24.174 1.00 104.02 ? 18  TRP A O   1 
ATOM   111   C CB  . TRP A 1 18  ? -9.864  33.690  -22.178 1.00 101.38 ? 18  TRP A CB  1 
ATOM   112   C CG  . TRP A 1 18  ? -9.395  32.511  -21.368 1.00 90.16  ? 18  TRP A CG  1 
ATOM   113   C CD1 . TRP A 1 18  ? -9.143  31.250  -21.818 1.00 90.04  ? 18  TRP A CD1 1 
ATOM   114   C CD2 . TRP A 1 18  ? -9.129  32.492  -19.950 1.00 86.09  ? 18  TRP A CD2 1 
ATOM   115   N NE1 . TRP A 1 18  ? -8.736  30.449  -20.785 1.00 94.48  ? 18  TRP A NE1 1 
ATOM   116   C CE2 . TRP A 1 18  ? -8.717  31.182  -19.628 1.00 89.72  ? 18  TRP A CE2 1 
ATOM   117   C CE3 . TRP A 1 18  ? -9.195  33.448  -18.932 1.00 85.98  ? 18  TRP A CE3 1 
ATOM   118   C CZ2 . TRP A 1 18  ? -8.378  30.809  -18.331 1.00 89.62  ? 18  TRP A CZ2 1 
ATOM   119   C CZ3 . TRP A 1 18  ? -8.857  33.077  -17.650 1.00 84.11  ? 18  TRP A CZ3 1 
ATOM   120   C CH2 . TRP A 1 18  ? -8.460  31.776  -17.355 1.00 88.47  ? 18  TRP A CH2 1 
ATOM   121   N N   . ARG A 1 19  ? -12.648 35.744  -22.255 1.00 97.98  ? 19  ARG A N   1 
ATOM   122   C CA  . ARG A 1 19  ? -13.258 36.981  -22.805 1.00 90.77  ? 19  ARG A CA  1 
ATOM   123   C C   . ARG A 1 19  ? -13.917 37.791  -21.684 1.00 96.61  ? 19  ARG A C   1 
ATOM   124   O O   . ARG A 1 19  ? -13.857 37.357  -20.514 1.00 94.64  ? 19  ARG A O   1 
ATOM   125   C CB  . ARG A 1 19  ? -14.283 36.643  -23.890 1.00 50.00  ? 19  ARG A CB  1 
ATOM   126   N N   . HIS A 1 20  ? -14.524 38.926  -22.040 1.00 99.69  ? 20  HIS A N   1 
ATOM   127   C CA  . HIS A 1 20  ? -15.186 39.737  -21.033 1.00 94.86  ? 20  HIS A CA  1 
ATOM   128   C C   . HIS A 1 20  ? -16.622 39.263  -20.846 1.00 97.66  ? 20  HIS A C   1 
ATOM   129   O O   . HIS A 1 20  ? -17.233 38.649  -21.744 1.00 93.80  ? 20  HIS A O   1 
ATOM   130   C CB  . HIS A 1 20  ? -15.176 41.226  -21.411 1.00 94.10  ? 20  HIS A CB  1 
ATOM   131   C CG  . HIS A 1 20  ? -13.812 41.776  -21.721 1.00 97.98  ? 20  HIS A CG  1 
ATOM   132   N ND1 . HIS A 1 20  ? -13.123 42.646  -20.893 1.00 90.14  ? 20  HIS A ND1 1 
ATOM   133   C CD2 . HIS A 1 20  ? -13.029 41.598  -22.796 1.00 99.31  ? 20  HIS A CD2 1 
ATOM   134   C CE1 . HIS A 1 20  ? -11.961 42.960  -21.449 1.00 86.15  ? 20  HIS A CE1 1 
ATOM   135   N NE2 . HIS A 1 20  ? -11.879 42.338  -22.605 1.00 91.48  ? 20  HIS A NE2 1 
ATOM   136   N N   . GLY A 1 21  ? -17.149 39.572  -19.674 1.00 95.14  ? 21  GLY A N   1 
ATOM   137   C CA  . GLY A 1 21  ? -18.522 39.303  -19.357 1.00 95.00  ? 21  GLY A CA  1 
ATOM   138   C C   . GLY A 1 21  ? -19.461 40.194  -20.152 1.00 92.54  ? 21  GLY A C   1 
ATOM   139   O O   . GLY A 1 21  ? -19.138 41.350  -20.457 1.00 80.33  ? 21  GLY A O   1 
ATOM   140   N N   . ARG A 1 22  ? -20.672 39.664  -20.324 1.00 93.30  ? 22  ARG A N   1 
ATOM   141   C CA  . ARG A 1 22  ? -21.724 40.190  -21.181 1.00 104.70 ? 22  ARG A CA  1 
ATOM   142   C C   . ARG A 1 22  ? -22.665 41.121  -20.405 1.00 110.42 ? 22  ARG A C   1 
ATOM   143   O O   . ARG A 1 22  ? -23.563 41.724  -20.992 1.00 123.38 ? 22  ARG A O   1 
ATOM   144   C CB  . ARG A 1 22  ? -22.521 39.046  -21.812 1.00 50.00  ? 22  ARG A CB  1 
ATOM   145   C CG  . ARG A 1 22  ? -22.874 39.269  -23.273 1.00 50.00  ? 22  ARG A CG  1 
ATOM   146   C CD  . ARG A 1 22  ? -23.707 38.155  -23.888 1.00 50.00  ? 22  ARG A CD  1 
ATOM   147   N NE  . ARG A 1 22  ? -23.961 38.380  -25.308 1.00 50.00  ? 22  ARG A NE  1 
ATOM   148   C CZ  . ARG A 1 22  ? -24.561 37.509  -26.104 1.00 50.00  ? 22  ARG A CZ  1 
ATOM   149   N NH1 . ARG A 1 22  ? -24.979 36.344  -25.623 1.00 50.00  ? 22  ARG A NH1 1 
ATOM   150   N NH2 . ARG A 1 22  ? -24.751 37.797  -27.386 1.00 50.00  ? 22  ARG A NH2 1 
ATOM   151   N N   . ALA A 1 23  ? -22.484 41.170  -19.076 1.00 113.57 ? 23  ALA A N   1 
ATOM   152   C CA  . ALA A 1 23  ? -23.393 41.864  -18.163 1.00 112.97 ? 23  ALA A CA  1 
ATOM   153   C C   . ALA A 1 23  ? -23.254 43.391  -18.285 1.00 103.91 ? 23  ALA A C   1 
ATOM   154   O O   . ALA A 1 23  ? -24.191 44.120  -17.980 1.00 100.12 ? 23  ALA A O   1 
ATOM   155   C CB  . ALA A 1 23  ? -23.122 41.407  -16.738 1.00 116.13 ? 23  ALA A CB  1 
ATOM   156   N N   . GLY A 1 24  ? -22.050 43.864  -18.641 1.00 101.42 ? 24  GLY A N   1 
ATOM   157   C CA  . GLY A 1 24  ? -21.816 45.283  -18.889 1.00 103.20 ? 24  GLY A CA  1 
ATOM   158   C C   . GLY A 1 24  ? -21.573 46.062  -17.594 1.00 106.07 ? 24  GLY A C   1 
ATOM   159   O O   . GLY A 1 24  ? -21.660 47.282  -17.585 1.00 112.23 ? 24  GLY A O   1 
ATOM   160   N N   . ARG A 1 25  ? -21.239 45.336  -16.513 1.00 115.60 ? 25  ARG A N   1 
ATOM   161   C CA  . ARG A 1 25  ? -20.885 45.939  -15.227 1.00 112.28 ? 25  ARG A CA  1 
ATOM   162   C C   . ARG A 1 25  ? -19.442 45.556  -14.876 1.00 112.59 ? 25  ARG A C   1 
ATOM   163   O O   . ARG A 1 25  ? -18.992 44.461  -15.227 1.00 140.68 ? 25  ARG A O   1 
ATOM   164   C CB  . ARG A 1 25  ? -21.855 45.454  -14.140 1.00 110.24 ? 25  ARG A CB  1 
ATOM   165   C CG  . ARG A 1 25  ? -23.299 45.903  -14.340 1.00 114.04 ? 25  ARG A CG  1 
ATOM   166   C CD  . ARG A 1 25  ? -24.301 45.187  -13.413 1.00 119.18 ? 25  ARG A CD  1 
ATOM   167   N NE  . ARG A 1 25  ? -24.511 45.890  -12.139 1.00 120.78 ? 25  ARG A NE  1 
ATOM   168   C CZ  . ARG A 1 25  ? -25.055 47.107  -12.015 1.00 121.66 ? 25  ARG A CZ  1 
ATOM   169   N NH1 . ARG A 1 25  ? -25.489 47.753  -13.086 1.00 125.77 ? 25  ARG A NH1 1 
ATOM   170   N NH2 . ARG A 1 25  ? -25.158 47.671  -10.824 1.00 118.35 ? 25  ARG A NH2 1 
ATOM   171   N N   . ARG A 1 26  ? -18.725 46.464  -14.185 1.00 102.02 ? 26  ARG A N   1 
ATOM   172   C CA  . ARG A 1 26  ? -17.305 46.278  -13.926 1.00 101.26 ? 26  ARG A CA  1 
ATOM   173   C C   . ARG A 1 26  ? -17.063 46.149  -12.442 1.00 101.40 ? 26  ARG A C   1 
ATOM   174   O O   . ARG A 1 26  ? -17.666 46.851  -11.648 1.00 106.91 ? 26  ARG A O   1 
ATOM   175   C CB  . ARG A 1 26  ? -16.529 47.389  -14.613 1.00 104.55 ? 26  ARG A CB  1 
ATOM   176   C CG  . ARG A 1 26  ? -16.694 47.066  -16.078 1.00 117.08 ? 26  ARG A CG  1 
ATOM   177   C CD  . ARG A 1 26  ? -16.484 48.177  -17.037 1.00 120.03 ? 26  ARG A CD  1 
ATOM   178   N NE  . ARG A 1 26  ? -15.403 47.887  -17.987 1.00 121.25 ? 26  ARG A NE  1 
ATOM   179   C CZ  . ARG A 1 26  ? -15.238 48.495  -19.165 1.00 125.20 ? 26  ARG A CZ  1 
ATOM   180   N NH1 . ARG A 1 26  ? -15.972 49.555  -19.476 1.00 129.79 ? 26  ARG A NH1 1 
ATOM   181   N NH2 . ARG A 1 26  ? -14.343 48.035  -20.025 1.00 114.54 ? 26  ARG A NH2 1 
ATOM   182   N N   . LEU A 1 27  ? -16.215 45.181  -12.087 1.00 106.56 ? 27  LEU A N   1 
ATOM   183   C CA  . LEU A 1 27  ? -15.877 44.905  -10.704 1.00 110.76 ? 27  LEU A CA  1 
ATOM   184   C C   . LEU A 1 27  ? -14.427 45.318  -10.475 1.00 106.29 ? 27  LEU A C   1 
ATOM   185   O O   . LEU A 1 27  ? -13.553 45.027  -11.293 1.00 105.44 ? 27  LEU A O   1 
ATOM   186   C CB  . LEU A 1 27  ? -16.118 43.409  -10.427 1.00 122.30 ? 27  LEU A CB  1 
ATOM   187   C CG  . LEU A 1 27  ? -15.592 42.838  -9.094  1.00 131.26 ? 27  LEU A CG  1 
ATOM   188   C CD1 . LEU A 1 27  ? -15.857 43.748  -7.898  1.00 136.86 ? 27  LEU A CD1 1 
ATOM   189   C CD2 . LEU A 1 27  ? -16.208 41.463  -8.849  1.00 131.61 ? 27  LEU A CD2 1 
ATOM   190   N N   . LYS A 1 28  ? -14.194 46.049  -9.396  1.00 102.25 ? 28  LYS A N   1 
ATOM   191   C CA  . LYS A 1 28  ? -12.849 46.369  -8.993  1.00 114.66 ? 28  LYS A CA  1 
ATOM   192   C C   . LYS A 1 28  ? -12.393 45.391  -7.932  1.00 108.15 ? 28  LYS A C   1 
ATOM   193   O O   . LYS A 1 28  ? -13.132 45.084  -7.000  1.00 93.52  ? 28  LYS A O   1 
ATOM   194   C CB  . LYS A 1 28  ? -12.814 47.822  -8.575  1.00 124.27 ? 28  LYS A CB  1 
ATOM   195   C CG  . LYS A 1 28  ? -13.026 48.692  -9.742  1.00 136.74 ? 28  LYS A CG  1 
ATOM   196   C CD  . LYS A 1 28  ? -13.703 49.997  -9.418  1.00 137.17 ? 28  LYS A CD  1 
ATOM   197   C CE  . LYS A 1 28  ? -13.276 51.070  -10.342 1.00 131.99 ? 28  LYS A CE  1 
ATOM   198   N NZ  . LYS A 1 28  ? -13.813 52.362  -9.922  1.00 133.68 ? 28  LYS A NZ  1 
ATOM   199   N N   . VAL A 1 29  ? -11.188 44.859  -8.134  1.00 99.93  ? 29  VAL A N   1 
ATOM   200   C CA  . VAL A 1 29  ? -10.563 43.972  -7.182  1.00 99.83  ? 29  VAL A CA  1 
ATOM   201   C C   . VAL A 1 29  ? -9.378  44.702  -6.577  1.00 86.21  ? 29  VAL A C   1 
ATOM   202   O O   . VAL A 1 29  ? -8.526  45.203  -7.302  1.00 90.62  ? 29  VAL A O   1 
ATOM   203   C CB  . VAL A 1 29  ? -10.133 42.657  -7.855  1.00 104.62 ? 29  VAL A CB  1 
ATOM   204   C CG1 . VAL A 1 29  ? -9.687  41.609  -6.834  1.00 106.29 ? 29  VAL A CG1 1 
ATOM   205   C CG2 . VAL A 1 29  ? -11.230 42.102  -8.757  1.00 97.40  ? 29  VAL A CG2 1 
ATOM   206   N N   . SER A 1 30  ? -9.359  44.785  -5.246  1.00 78.95  ? 30  SER A N   1 
ATOM   207   C CA  . SER A 1 30  ? -8.458  45.685  -4.546  1.00 86.80  ? 30  SER A CA  1 
ATOM   208   C C   . SER A 1 30  ? -7.761  44.958  -3.399  1.00 76.19  ? 30  SER A C   1 
ATOM   209   O O   . SER A 1 30  ? -8.300  44.010  -2.833  1.00 81.72  ? 30  SER A O   1 
ATOM   210   C CB  . SER A 1 30  ? -9.194  46.906  -4.055  1.00 96.53  ? 30  SER A CB  1 
ATOM   211   O OG  . SER A 1 30  ? -10.481 46.562  -3.562  1.00 104.09 ? 30  SER A OG  1 
ATOM   212   N N   . ASN A 1 31  ? -6.559  45.439  -3.066  1.00 69.32  ? 31  ASN A N   1 
ATOM   213   C CA  . ASN A 1 31  ? -5.767  44.922  -1.961  1.00 67.66  ? 31  ASN A CA  1 
ATOM   214   C C   . ASN A 1 31  ? -6.386  45.396  -0.641  1.00 77.18  ? 31  ASN A C   1 
ATOM   215   O O   . ASN A 1 31  ? -6.601  46.579  -0.454  1.00 89.26  ? 31  ASN A O   1 
ATOM   216   C CB  . ASN A 1 31  ? -4.320  45.385  -2.087  1.00 63.55  ? 31  ASN A CB  1 
ATOM   217   C CG  . ASN A 1 31  ? -3.384  44.634  -1.181  1.00 72.32  ? 31  ASN A CG  1 
ATOM   218   O OD1 . ASN A 1 31  ? -3.596  44.580  0.038   1.00 80.50  ? 31  ASN A OD1 1 
ATOM   219   N ND2 . ASN A 1 31  ? -2.340  44.057  -1.748  1.00 83.28  ? 31  ASN A ND2 1 
ATOM   220   N N   . PRO A 1 32  ? -6.692  44.501  0.323   1.00 89.84  ? 32  PRO A N   1 
ATOM   221   C CA  . PRO A 1 32  ? -7.249  44.938  1.599   1.00 90.71  ? 32  PRO A CA  1 
ATOM   222   C C   . PRO A 1 32  ? -6.284  45.797  2.412   1.00 91.19  ? 32  PRO A C   1 
ATOM   223   O O   . PRO A 1 32  ? -6.717  46.664  3.149   1.00 104.96 ? 32  PRO A O   1 
ATOM   224   C CB  . PRO A 1 32  ? -7.607  43.631  2.316   1.00 97.92  ? 32  PRO A CB  1 
ATOM   225   C CG  . PRO A 1 32  ? -6.703  42.596  1.668   1.00 97.28  ? 32  PRO A CG  1 
ATOM   226   C CD  . PRO A 1 32  ? -6.564  43.043  0.227   1.00 93.38  ? 32  PRO A CD  1 
ATOM   227   N N   . PHE A 1 33  ? -4.972  45.560  2.261   1.00 91.52  ? 33  PHE A N   1 
ATOM   228   C CA  . PHE A 1 33  ? -3.983  46.315  3.025   1.00 100.74 ? 33  PHE A CA  1 
ATOM   229   C C   . PHE A 1 33  ? -3.948  47.772  2.532   1.00 106.92 ? 33  PHE A C   1 
ATOM   230   O O   . PHE A 1 33  ? -4.360  48.675  3.257   1.00 101.11 ? 33  PHE A O   1 
ATOM   231   C CB  . PHE A 1 33  ? -2.591  45.683  2.964   1.00 101.78 ? 33  PHE A CB  1 
ATOM   232   C CG  . PHE A 1 33  ? -1.575  46.378  3.861   1.00 103.51 ? 33  PHE A CG  1 
ATOM   233   C CD1 . PHE A 1 33  ? -1.903  46.727  5.170   1.00 103.16 ? 33  PHE A CD1 1 
ATOM   234   C CD2 . PHE A 1 33  ? -0.311  46.724  3.384   1.00 97.01  ? 33  PHE A CD2 1 
ATOM   235   C CE1 . PHE A 1 33  ? -0.979  47.363  5.988   1.00 103.59 ? 33  PHE A CE1 1 
ATOM   236   C CE2 . PHE A 1 33  ? 0.605   47.365  4.210   1.00 95.35  ? 33  PHE A CE2 1 
ATOM   237   C CZ  . PHE A 1 33  ? 0.264   47.689  5.505   1.00 98.05  ? 33  PHE A CZ  1 
ATOM   238   N N   . ASP A 1 34  ? -3.445  47.986  1.298   1.00 105.59 ? 34  ASP A N   1 
ATOM   239   C CA  . ASP A 1 34  ? -3.205  49.331  0.779   1.00 93.92  ? 34  ASP A CA  1 
ATOM   240   C C   . ASP A 1 34  ? -4.509  49.950  0.281   1.00 86.94  ? 34  ASP A C   1 
ATOM   241   O O   . ASP A 1 34  ? -4.603  51.155  0.136   1.00 88.84  ? 34  ASP A O   1 
ATOM   242   C CB  . ASP A 1 34  ? -2.192  49.324  -0.350  1.00 94.21  ? 34  ASP A CB  1 
ATOM   243   C CG  . ASP A 1 34  ? -0.815  48.799  0.008   1.00 95.69  ? 34  ASP A CG  1 
ATOM   244   O OD1 . ASP A 1 34  ? -0.411  47.780  -0.574  1.00 87.97  ? 34  ASP A OD1 1 
ATOM   245   O OD2 . ASP A 1 34  ? -0.156  49.425  0.849   1.00 106.56 ? 34  ASP A OD2 1 
ATOM   246   N N   . GLY A 1 35  ? -5.473  49.108  -0.075  1.00 86.47  ? 35  GLY A N   1 
ATOM   247   C CA  . GLY A 1 35  ? -6.667  49.569  -0.769  1.00 83.08  ? 35  GLY A CA  1 
ATOM   248   C C   . GLY A 1 35  ? -6.411  49.778  -2.268  1.00 80.69  ? 35  GLY A C   1 
ATOM   249   O O   . GLY A 1 35  ? -7.335  50.139  -3.008  1.00 79.58  ? 35  GLY A O   1 
ATOM   250   N N   . SER A 1 36  ? -5.159  49.503  -2.714  1.00 80.60  ? 36  SER A N   1 
ATOM   251   C CA  . SER A 1 36  ? -4.746  49.770  -4.091  1.00 84.13  ? 36  SER A CA  1 
ATOM   252   C C   . SER A 1 36  ? -5.423  48.786  -5.041  1.00 84.09  ? 36  SER A C   1 
ATOM   253   O O   . SER A 1 36  ? -5.611  47.620  -4.702  1.00 98.36  ? 36  SER A O   1 
ATOM   254   C CB  . SER A 1 36  ? -3.237  49.723  -4.241  1.00 84.32  ? 36  SER A CB  1 
ATOM   255   O OG  . SER A 1 36  ? -2.738  48.425  -3.983  1.00 77.08  ? 36  SER A OG  1 
ATOM   256   N N   . LEU A 1 37  ? -5.782  49.282  -6.230  1.00 84.87  ? 37  LEU A N   1 
ATOM   257   C CA  . LEU A 1 37  ? -6.568  48.521  -7.194  1.00 91.07  ? 37  LEU A CA  1 
ATOM   258   C C   . LEU A 1 37  ? -5.674  47.477  -7.892  1.00 91.07  ? 37  LEU A C   1 
ATOM   259   O O   . LEU A 1 37  ? -4.663  47.820  -8.508  1.00 70.55  ? 37  LEU A O   1 
ATOM   260   C CB  . LEU A 1 37  ? -7.217  49.495  -8.187  1.00 85.01  ? 37  LEU A CB  1 
ATOM   261   C CG  . LEU A 1 37  ? -7.843  48.877  -9.445  1.00 94.46  ? 37  LEU A CG  1 
ATOM   262   C CD1 . LEU A 1 37  ? -9.180  49.534  -9.774  1.00 97.68  ? 37  LEU A CD1 1 
ATOM   263   C CD2 . LEU A 1 37  ? -6.897  48.976  -10.646 1.00 89.07  ? 37  LEU A CD2 1 
ATOM   264   N N   . LEU A 1 38  ? -6.080  46.198  -7.779  1.00 97.57  ? 38  LEU A N   1 
ATOM   265   C CA  . LEU A 1 38  ? -5.369  45.079  -8.389  1.00 98.32  ? 38  LEU A CA  1 
ATOM   266   C C   . LEU A 1 38  ? -5.705  44.998  -9.886  1.00 89.23  ? 38  LEU A C   1 
ATOM   267   O O   . LEU A 1 38  ? -4.816  45.101  -10.732 1.00 80.21  ? 38  LEU A O   1 
ATOM   268   C CB  . LEU A 1 38  ? -5.748  43.787  -7.659  1.00 100.39 ? 38  LEU A CB  1 
ATOM   269   C CG  . LEU A 1 38  ? -4.996  43.492  -6.354  1.00 103.28 ? 38  LEU A CG  1 
ATOM   270   C CD1 . LEU A 1 38  ? -3.644  42.945  -6.664  1.00 106.77 ? 38  LEU A CD1 1 
ATOM   271   C CD2 . LEU A 1 38  ? -4.859  44.682  -5.461  1.00 102.83 ? 38  LEU A CD2 1 
ATOM   272   N N   . LEU A 1 39  ? -6.989  44.758  -10.196 1.00 76.07  ? 39  LEU A N   1 
ATOM   273   C CA  . LEU A 1 39  ? -7.441  44.642  -11.573 1.00 77.22  ? 39  LEU A CA  1 
ATOM   274   C C   . LEU A 1 39  ? -8.958  44.819  -11.618 1.00 74.89  ? 39  LEU A C   1 
ATOM   275   O O   . LEU A 1 39  ? -9.609  44.959  -10.567 1.00 66.72  ? 39  LEU A O   1 
ATOM   276   C CB  . LEU A 1 39  ? -6.990  43.305  -12.191 1.00 91.39  ? 39  LEU A CB  1 
ATOM   277   C CG  . LEU A 1 39  ? -7.921  42.088  -12.010 1.00 106.55 ? 39  LEU A CG  1 
ATOM   278   C CD1 . LEU A 1 39  ? -7.360  40.869  -12.754 1.00 108.87 ? 39  LEU A CD1 1 
ATOM   279   C CD2 . LEU A 1 39  ? -8.158  41.738  -10.543 1.00 111.85 ? 39  LEU A CD2 1 
ATOM   280   N N   . GLU A 1 40  ? -9.505  44.852  -12.850 1.00 77.53  ? 40  GLU A N   1 
ATOM   281   C CA  . GLU A 1 40  ? -10.920 45.109  -13.068 1.00 81.27  ? 40  GLU A CA  1 
ATOM   282   C C   . GLU A 1 40  ? -11.477 44.060  -14.014 1.00 77.92  ? 40  GLU A C   1 
ATOM   283   O O   . GLU A 1 40  ? -10.833 43.710  -14.990 1.00 75.85  ? 40  GLU A O   1 
ATOM   284   C CB  . GLU A 1 40  ? -11.145 46.504  -13.655 1.00 97.19  ? 40  GLU A CB  1 
ATOM   285   C CG  . GLU A 1 40  ? -10.838 47.637  -12.678 1.00 107.64 ? 40  GLU A CG  1 
ATOM   286   C CD  . GLU A 1 40  ? -11.356 48.996  -13.122 1.00 109.76 ? 40  GLU A CD  1 
ATOM   287   O OE1 . GLU A 1 40  ? -12.570 49.268  -12.943 1.00 110.37 ? 40  GLU A OE1 1 
ATOM   288   O OE2 . GLU A 1 40  ? -10.549 49.767  -13.683 1.00 106.76 ? 40  GLU A OE2 1 
ATOM   289   N N   . ILE A 1 41  ? -12.707 43.600  -13.722 1.00 87.07  ? 41  ILE A N   1 
ATOM   290   C CA  . ILE A 1 41  ? -13.327 42.489  -14.437 1.00 93.90  ? 41  ILE A CA  1 
ATOM   291   C C   . ILE A 1 41  ? -14.699 42.939  -14.942 1.00 98.96  ? 41  ILE A C   1 
ATOM   292   O O   . ILE A 1 41  ? -15.461 43.566  -14.197 1.00 114.98 ? 41  ILE A O   1 
ATOM   293   C CB  . ILE A 1 41  ? -13.464 41.234  -13.534 1.00 91.22  ? 41  ILE A CB  1 
ATOM   294   C CG1 . ILE A 1 41  ? -12.189 40.944  -12.719 1.00 93.80  ? 41  ILE A CG1 1 
ATOM   295   C CG2 . ILE A 1 41  ? -13.891 40.019  -14.356 1.00 85.79  ? 41  ILE A CG2 1 
ATOM   296   C CD1 . ILE A 1 41  ? -12.305 39.724  -11.801 1.00 94.30  ? 41  ILE A CD1 1 
ATOM   297   N N   . GLU A 1 42  ? -15.025 42.551  -16.191 1.00 95.31  ? 42  GLU A N   1 
ATOM   298   C CA  . GLU A 1 42  ? -16.374 42.687  -16.729 1.00 98.96  ? 42  GLU A CA  1 
ATOM   299   C C   . GLU A 1 42  ? -17.258 41.560  -16.209 1.00 105.40 ? 42  GLU A C   1 
ATOM   300   O O   . GLU A 1 42  ? -17.017 40.395  -16.510 1.00 116.41 ? 42  GLU A O   1 
ATOM   301   C CB  . GLU A 1 42  ? -16.356 42.619  -18.251 1.00 102.37 ? 42  GLU A CB  1 
ATOM   302   C CG  . GLU A 1 42  ? -15.806 43.877  -18.900 1.00 109.98 ? 42  GLU A CG  1 
ATOM   303   C CD  . GLU A 1 42  ? -16.735 45.068  -18.799 1.00 116.70 ? 42  GLU A CD  1 
ATOM   304   O OE1 . GLU A 1 42  ? -17.751 44.964  -18.078 1.00 119.99 ? 42  GLU A OE1 1 
ATOM   305   O OE2 . GLU A 1 42  ? -16.462 46.079  -19.460 1.00 121.93 ? 42  GLU A OE2 1 
ATOM   306   N N   . GLN A 1 43  ? -18.323 41.924  -15.492 1.00 101.43 ? 43  GLN A N   1 
ATOM   307   C CA  . GLN A 1 43  ? -19.199 40.944  -14.859 1.00 98.18  ? 43  GLN A CA  1 
ATOM   308   C C   . GLN A 1 43  ? -19.931 40.140  -15.942 1.00 95.85  ? 43  GLN A C   1 
ATOM   309   O O   . GLN A 1 43  ? -20.092 40.612  -17.071 1.00 79.56  ? 43  GLN A O   1 
ATOM   310   C CB  . GLN A 1 43  ? -20.201 41.633  -13.926 1.00 108.73 ? 43  GLN A CB  1 
ATOM   311   C CG  . GLN A 1 43  ? -19.565 42.549  -12.874 1.00 108.59 ? 43  GLN A CG  1 
ATOM   312   C CD  . GLN A 1 43  ? -19.802 42.091  -11.451 1.00 102.89 ? 43  GLN A CD  1 
ATOM   313   O OE1 . GLN A 1 43  ? -19.275 41.067  -11.007 1.00 108.22 ? 43  GLN A OE1 1 
ATOM   314   N NE2 . GLN A 1 43  ? -20.589 42.863  -10.712 1.00 95.51  ? 43  GLN A NE2 1 
ATOM   315   N N   . ALA A 1 44  ? -20.360 38.915  -15.579 1.00 91.90  ? 44  ALA A N   1 
ATOM   316   C CA  . ALA A 1 44  ? -21.011 38.002  -16.511 1.00 91.10  ? 44  ALA A CA  1 
ATOM   317   C C   . ALA A 1 44  ? -22.510 37.971  -16.247 1.00 89.62  ? 44  ALA A C   1 
ATOM   318   O O   . ALA A 1 44  ? -22.942 38.052  -15.099 1.00 95.25  ? 44  ALA A O   1 
ATOM   319   C CB  . ALA A 1 44  ? -20.410 36.619  -16.387 1.00 95.23  ? 44  ALA A CB  1 
ATOM   320   N N   . ASP A 1 45  ? -23.290 37.835  -17.327 1.00 90.61  ? 45  ASP A N   1 
ATOM   321   C CA  . ASP A 1 45  ? -24.747 37.826  -17.244 1.00 99.03  ? 45  ASP A CA  1 
ATOM   322   C C   . ASP A 1 45  ? -25.240 36.377  -17.200 1.00 101.11 ? 45  ASP A C   1 
ATOM   323   O O   . ASP A 1 45  ? -24.447 35.445  -17.275 1.00 94.08  ? 45  ASP A O   1 
ATOM   324   C CB  . ASP A 1 45  ? -25.362 38.601  -18.402 1.00 102.63 ? 45  ASP A CB  1 
ATOM   325   C CG  . ASP A 1 45  ? -25.018 38.074  -19.788 1.00 107.26 ? 45  ASP A CG  1 
ATOM   326   O OD1 . ASP A 1 45  ? -24.445 36.950  -19.864 1.00 95.75  ? 45  ASP A OD1 1 
ATOM   327   O OD2 . ASP A 1 45  ? -25.299 38.792  -20.781 1.00 110.81 ? 45  ASP A OD2 1 
ATOM   328   N N   . ARG A 1 46  ? -26.571 36.209  -17.115 1.00 109.71 ? 46  ARG A N   1 
ATOM   329   C CA  . ARG A 1 46  ? -27.182 34.889  -17.006 1.00 113.43 ? 46  ARG A CA  1 
ATOM   330   C C   . ARG A 1 46  ? -27.063 34.135  -18.341 1.00 109.51 ? 46  ARG A C   1 
ATOM   331   O O   . ARG A 1 46  ? -27.054 32.911  -18.357 1.00 112.75 ? 46  ARG A O   1 
ATOM   332   C CB  . ARG A 1 46  ? -28.648 34.991  -16.562 1.00 120.90 ? 46  ARG A CB  1 
ATOM   333   C CG  . ARG A 1 46  ? -29.153 33.733  -15.869 1.00 128.94 ? 46  ARG A CG  1 
ATOM   334   C CD  . ARG A 1 46  ? -30.643 33.765  -15.577 1.00 129.60 ? 46  ARG A CD  1 
ATOM   335   N NE  . ARG A 1 46  ? -30.966 34.406  -14.294 1.00 131.76 ? 46  ARG A NE  1 
ATOM   336   C CZ  . ARG A 1 46  ? -31.902 33.978  -13.442 1.00 129.41 ? 46  ARG A CZ  1 
ATOM   337   N NH1 . ARG A 1 46  ? -32.641 32.921  -13.740 1.00 129.32 ? 46  ARG A NH1 1 
ATOM   338   N NH2 . ARG A 1 46  ? -32.104 34.618  -12.302 1.00 129.48 ? 46  ARG A NH2 1 
ATOM   339   N N   . ASP A 1 47  ? -26.956 34.870  -19.449 1.00 110.04 ? 47  ASP A N   1 
ATOM   340   C CA  . ASP A 1 47  ? -26.750 34.251  -20.756 1.00 115.83 ? 47  ASP A CA  1 
ATOM   341   C C   . ASP A 1 47  ? -25.364 33.597  -20.787 1.00 111.05 ? 47  ASP A C   1 
ATOM   342   O O   . ASP A 1 47  ? -25.181 32.536  -21.393 1.00 108.54 ? 47  ASP A O   1 
ATOM   343   C CB  . ASP A 1 47  ? -26.937 35.258  -21.881 1.00 122.23 ? 47  ASP A CB  1 
ATOM   344   C CG  . ASP A 1 47  ? -28.019 36.302  -21.644 1.00 122.03 ? 47  ASP A CG  1 
ATOM   345   O OD1 . ASP A 1 47  ? -29.155 35.903  -21.335 1.00 131.99 ? 47  ASP A OD1 1 
ATOM   346   O OD2 . ASP A 1 47  ? -27.704 37.502  -21.734 1.00 107.77 ? 47  ASP A OD2 1 
ATOM   347   N N   . ASP A 1 48  ? -24.397 34.238  -20.113 1.00 109.24 ? 48  ASP A N   1 
ATOM   348   C CA  . ASP A 1 48  ? -23.053 33.694  -19.981 1.00 105.37 ? 48  ASP A CA  1 
ATOM   349   C C   . ASP A 1 48  ? -23.085 32.369  -19.218 1.00 95.05  ? 48  ASP A C   1 
ATOM   350   O O   . ASP A 1 48  ? -22.429 31.416  -19.615 1.00 83.17  ? 48  ASP A O   1 
ATOM   351   C CB  . ASP A 1 48  ? -22.124 34.658  -19.276 1.00 109.26 ? 48  ASP A CB  1 
ATOM   352   C CG  . ASP A 1 48  ? -21.588 35.791  -20.131 1.00 103.65 ? 48  ASP A CG  1 
ATOM   353   O OD1 . ASP A 1 48  ? -21.248 35.533  -21.305 1.00 89.87  ? 48  ASP A OD1 1 
ATOM   354   O OD2 . ASP A 1 48  ? -21.438 36.894  -19.589 1.00 91.82  ? 48  ASP A OD2 1 
ATOM   355   N N   . LEU A 1 49  ? -23.822 32.341  -18.099 1.00 96.53  ? 49  LEU A N   1 
ATOM   356   C CA  . LEU A 1 49  ? -23.856 31.182  -17.208 1.00 99.47  ? 49  LEU A CA  1 
ATOM   357   C C   . LEU A 1 49  ? -24.416 29.965  -17.956 1.00 101.51 ? 49  LEU A C   1 
ATOM   358   O O   . LEU A 1 49  ? -23.878 28.859  -17.838 1.00 99.59  ? 49  LEU A O   1 
ATOM   359   C CB  . LEU A 1 49  ? -24.685 31.513  -15.963 1.00 102.12 ? 49  LEU A CB  1 
ATOM   360   C CG  . LEU A 1 49  ? -25.026 30.339  -15.033 1.00 94.77  ? 49  LEU A CG  1 
ATOM   361   C CD1 . LEU A 1 49  ? -23.771 29.682  -14.479 1.00 102.29 ? 49  LEU A CD1 1 
ATOM   362   C CD2 . LEU A 1 49  ? -25.924 30.793  -13.901 1.00 84.76  ? 49  LEU A CD2 1 
ATOM   363   N N   . ASP A 1 50  ? -25.501 30.179  -18.721 1.00 96.36  ? 50  ASP A N   1 
ATOM   364   C CA  . ASP A 1 50  ? -26.120 29.114  -19.501 1.00 87.86  ? 50  ASP A CA  1 
ATOM   365   C C   . ASP A 1 50  ? -25.111 28.534  -20.498 1.00 80.70  ? 50  ASP A C   1 
ATOM   366   O O   . ASP A 1 50  ? -25.064 27.317  -20.696 1.00 75.70  ? 50  ASP A O   1 
ATOM   367   C CB  . ASP A 1 50  ? -27.396 29.591  -20.166 1.00 94.38  ? 50  ASP A CB  1 
ATOM   368   C CG  . ASP A 1 50  ? -28.640 29.507  -19.291 1.00 107.68 ? 50  ASP A CG  1 
ATOM   369   O OD1 . ASP A 1 50  ? -29.671 29.012  -19.789 1.00 116.03 ? 50  ASP A OD1 1 
ATOM   370   O OD2 . ASP A 1 50  ? -28.554 29.898  -18.097 1.00 103.14 ? 50  ASP A OD2 1 
ATOM   371   N N   . ALA A 1 51  ? -24.291 29.408  -21.100 1.00 75.76  ? 51  ALA A N   1 
ATOM   372   C CA  . ALA A 1 51  ? -23.293 28.983  -22.076 1.00 80.63  ? 51  ALA A CA  1 
ATOM   373   C C   . ALA A 1 51  ? -22.231 28.085  -21.416 1.00 87.15  ? 51  ALA A C   1 
ATOM   374   O O   . ALA A 1 51  ? -21.826 27.077  -21.996 1.00 91.88  ? 51  ALA A O   1 
ATOM   375   C CB  . ALA A 1 51  ? -22.664 30.189  -22.729 1.00 78.07  ? 51  ALA A CB  1 
ATOM   376   N N   . ALA A 1 52  ? -21.779 28.469  -20.203 1.00 87.45  ? 52  ALA A N   1 
ATOM   377   C CA  . ALA A 1 52  ? -20.713 27.750  -19.495 1.00 81.35  ? 52  ALA A CA  1 
ATOM   378   C C   . ALA A 1 52  ? -21.142 26.306  -19.178 1.00 71.43  ? 52  ALA A C   1 
ATOM   379   O O   . ALA A 1 52  ? -20.376 25.377  -19.388 1.00 63.61  ? 52  ALA A O   1 
ATOM   380   C CB  . ALA A 1 52  ? -20.332 28.499  -18.237 1.00 83.56  ? 52  ALA A CB  1 
ATOM   381   N N   . TYR A 1 53  ? -22.386 26.137  -18.697 1.00 68.60  ? 53  TYR A N   1 
ATOM   382   C CA  . TYR A 1 53  ? -22.922 24.823  -18.384 1.00 65.62  ? 53  TYR A CA  1 
ATOM   383   C C   . TYR A 1 53  ? -23.118 24.022  -19.666 1.00 69.14  ? 53  TYR A C   1 
ATOM   384   O O   . TYR A 1 53  ? -22.849 22.823  -19.690 1.00 76.61  ? 53  TYR A O   1 
ATOM   385   C CB  . TYR A 1 53  ? -24.228 24.932  -17.597 1.00 68.16  ? 53  TYR A CB  1 
ATOM   386   C CG  . TYR A 1 53  ? -24.037 25.024  -16.091 1.00 69.12  ? 53  TYR A CG  1 
ATOM   387   C CD1 . TYR A 1 53  ? -23.096 24.239  -15.437 1.00 69.25  ? 53  TYR A CD1 1 
ATOM   388   C CD2 . TYR A 1 53  ? -24.779 25.914  -15.328 1.00 71.66  ? 53  TYR A CD2 1 
ATOM   389   C CE1 . TYR A 1 53  ? -22.906 24.325  -14.069 1.00 69.12  ? 53  TYR A CE1 1 
ATOM   390   C CE2 . TYR A 1 53  ? -24.611 26.004  -13.955 1.00 75.52  ? 53  TYR A CE2 1 
ATOM   391   C CZ  . TYR A 1 53  ? -23.671 25.206  -13.321 1.00 75.99  ? 53  TYR A CZ  1 
ATOM   392   O OH  . TYR A 1 53  ? -23.498 25.290  -11.958 1.00 74.08  ? 53  TYR A OH  1 
ATOM   393   N N   . ALA A 1 54  ? -23.593 24.684  -20.727 1.00 69.46  ? 54  ALA A N   1 
ATOM   394   C CA  . ALA A 1 54  ? -23.876 24.000  -21.989 1.00 68.33  ? 54  ALA A CA  1 
ATOM   395   C C   . ALA A 1 54  ? -22.592 23.414  -22.546 1.00 68.04  ? 54  ALA A C   1 
ATOM   396   O O   . ALA A 1 54  ? -22.578 22.267  -22.991 1.00 62.32  ? 54  ALA A O   1 
ATOM   397   C CB  . ALA A 1 54  ? -24.518 24.953  -22.984 1.00 69.58  ? 54  ALA A CB  1 
ATOM   398   N N   . LYS A 1 55  ? -21.513 24.230  -22.509 1.00 70.31  ? 55  LYS A N   1 
ATOM   399   C CA  . LYS A 1 55  ? -20.230 23.854  -23.076 1.00 69.78  ? 55  LYS A CA  1 
ATOM   400   C C   . LYS A 1 55  ? -19.632 22.708  -22.267 1.00 69.24  ? 55  LYS A C   1 
ATOM   401   O O   . LYS A 1 55  ? -19.145 21.741  -22.827 1.00 69.14  ? 55  LYS A O   1 
ATOM   402   C CB  . LYS A 1 55  ? -19.265 25.047  -23.115 1.00 74.07  ? 55  LYS A CB  1 
ATOM   403   C CG  . LYS A 1 55  ? -18.042 24.860  -24.021 1.00 79.26  ? 55  LYS A CG  1 
ATOM   404   C CD  . LYS A 1 55  ? -18.380 24.180  -25.343 1.00 86.20  ? 55  LYS A CD  1 
ATOM   405   C CE  . LYS A 1 55  ? -17.639 24.745  -26.511 1.00 90.33  ? 55  LYS A CE  1 
ATOM   406   N NZ  . LYS A 1 55  ? -18.187 24.247  -27.776 1.00 87.64  ? 55  LYS A NZ  1 
ATOM   407   N N   . ALA A 1 56  ? -19.716 22.816  -20.947 1.00 66.69  ? 56  ALA A N   1 
ATOM   408   C CA  . ALA A 1 56  ? -19.174 21.804  -20.060 1.00 70.45  ? 56  ALA A CA  1 
ATOM   409   C C   . ALA A 1 56  ? -19.824 20.448  -20.351 1.00 71.84  ? 56  ALA A C   1 
ATOM   410   O O   . ALA A 1 56  ? -19.143 19.428  -20.373 1.00 70.09  ? 56  ALA A O   1 
ATOM   411   C CB  . ALA A 1 56  ? -19.373 22.223  -18.606 1.00 71.98  ? 56  ALA A CB  1 
ATOM   412   N N   . ALA A 1 57  ? -21.145 20.450  -20.566 1.00 66.16  ? 57  ALA A N   1 
ATOM   413   C CA  . ALA A 1 57  ? -21.884 19.219  -20.777 1.00 60.08  ? 57  ALA A CA  1 
ATOM   414   C C   . ALA A 1 57  ? -21.467 18.554  -22.098 1.00 62.02  ? 57  ALA A C   1 
ATOM   415   O O   . ALA A 1 57  ? -21.408 17.337  -22.182 1.00 70.10  ? 57  ALA A O   1 
ATOM   416   C CB  . ALA A 1 57  ? -23.359 19.498  -20.737 1.00 60.87  ? 57  ALA A CB  1 
ATOM   417   N N   . GLU A 1 58  ? -21.149 19.354  -23.117 1.00 70.39  ? 58  GLU A N   1 
ATOM   418   C CA  . GLU A 1 58  ? -20.925 18.803  -24.459 1.00 77.60  ? 58  GLU A CA  1 
ATOM   419   C C   . GLU A 1 58  ? -19.511 18.212  -24.562 1.00 73.11  ? 58  GLU A C   1 
ATOM   420   O O   . GLU A 1 58  ? -19.333 17.165  -25.163 1.00 72.71  ? 58  GLU A O   1 
ATOM   421   C CB  . GLU A 1 58  ? -21.207 19.807  -25.584 1.00 78.05  ? 58  GLU A CB  1 
ATOM   422   C CG  . GLU A 1 58  ? -20.538 21.164  -25.399 1.00 85.84  ? 58  GLU A CG  1 
ATOM   423   C CD  . GLU A 1 58  ? -20.887 22.155  -26.491 1.00 93.52  ? 58  GLU A CD  1 
ATOM   424   O OE1 . GLU A 1 58  ? -20.866 21.722  -27.669 1.00 94.97  ? 58  GLU A OE1 1 
ATOM   425   O OE2 . GLU A 1 58  ? -21.180 23.356  -26.175 1.00 83.04  ? 58  GLU A OE2 1 
ATOM   426   N N   . VAL A 1 59  ? -18.519 18.875  -23.936 1.00 69.76  ? 59  VAL A N   1 
ATOM   427   C CA  . VAL A 1 59  ? -17.109 18.502  -24.106 1.00 63.79  ? 59  VAL A CA  1 
ATOM   428   C C   . VAL A 1 59  ? -16.721 17.407  -23.101 1.00 62.81  ? 59  VAL A C   1 
ATOM   429   O O   . VAL A 1 59  ? -15.678 16.784  -23.252 1.00 60.92  ? 59  VAL A O   1 
ATOM   430   C CB  . VAL A 1 59  ? -16.152 19.699  -23.983 1.00 59.68  ? 59  VAL A CB  1 
ATOM   431   C CG1 . VAL A 1 59  ? -16.297 20.656  -25.149 1.00 69.25  ? 59  VAL A CG1 1 
ATOM   432   C CG2 . VAL A 1 59  ? -16.314 20.438  -22.665 1.00 65.32  ? 59  VAL A CG2 1 
ATOM   433   N N   . GLN A 1 60  ? -17.553 17.195  -22.070 1.00 60.82  ? 60  GLN A N   1 
ATOM   434   C CA  . GLN A 1 60  ? -17.196 16.315  -20.955 1.00 64.82  ? 60  GLN A CA  1 
ATOM   435   C C   . GLN A 1 60  ? -17.036 14.862  -21.438 1.00 61.66  ? 60  GLN A C   1 
ATOM   436   O O   . GLN A 1 60  ? -16.082 14.196  -21.048 1.00 58.44  ? 60  GLN A O   1 
ATOM   437   C CB  . GLN A 1 60  ? -18.199 16.452  -19.799 1.00 67.83  ? 60  GLN A CB  1 
ATOM   438   C CG  . GLN A 1 60  ? -18.014 15.438  -18.670 1.00 66.65  ? 60  GLN A CG  1 
ATOM   439   C CD  . GLN A 1 60  ? -18.806 14.174  -18.884 1.00 65.19  ? 60  GLN A CD  1 
ATOM   440   O OE1 . GLN A 1 60  ? -18.269 13.068  -18.876 1.00 68.40  ? 60  GLN A OE1 1 
ATOM   441   N NE2 . GLN A 1 60  ? -20.099 14.332  -19.092 1.00 68.48  ? 60  GLN A NE2 1 
ATOM   442   N N   . PRO A 1 61  ? -17.961 14.309  -22.262 1.00 57.91  ? 61  PRO A N   1 
ATOM   443   C CA  . PRO A 1 61  ? -17.855 12.910  -22.693 1.00 61.13  ? 61  PRO A CA  1 
ATOM   444   C C   . PRO A 1 61  ? -16.521 12.542  -23.349 1.00 59.95  ? 61  PRO A C   1 
ATOM   445   O O   . PRO A 1 61  ? -15.978 11.469  -23.098 1.00 68.82  ? 61  PRO A O   1 
ATOM   446   C CB  . PRO A 1 61  ? -19.032 12.774  -23.663 1.00 61.20  ? 61  PRO A CB  1 
ATOM   447   C CG  . PRO A 1 61  ? -20.039 13.752  -23.125 1.00 63.73  ? 61  PRO A CG  1 
ATOM   448   C CD  . PRO A 1 61  ? -19.194 14.948  -22.729 1.00 61.96  ? 61  PRO A CD  1 
ATOM   449   N N   . ALA A 1 62  ? -15.994 13.438  -24.171 1.00 61.43  ? 62  ALA A N   1 
ATOM   450   C CA  . ALA A 1 62  ? -14.725 13.197  -24.841 1.00 61.70  ? 62  ALA A CA  1 
ATOM   451   C C   . ALA A 1 62  ? -13.588 13.090  -23.806 1.00 58.92  ? 62  ALA A C   1 
ATOM   452   O O   . ALA A 1 62  ? -12.696 12.260  -23.939 1.00 64.25  ? 62  ALA A O   1 
ATOM   453   C CB  . ALA A 1 62  ? -14.463 14.298  -25.850 1.00 58.39  ? 62  ALA A CB  1 
ATOM   454   N N   . TRP A 1 63  ? -13.632 13.958  -22.794 1.00 53.79  ? 63  TRP A N   1 
ATOM   455   C CA  . TRP A 1 63  ? -12.662 13.951  -21.703 1.00 53.33  ? 63  TRP A CA  1 
ATOM   456   C C   . TRP A 1 63  ? -12.780 12.645  -20.903 1.00 59.96  ? 63  TRP A C   1 
ATOM   457   O O   . TRP A 1 63  ? -11.774 12.009  -20.609 1.00 65.18  ? 63  TRP A O   1 
ATOM   458   C CB  . TRP A 1 63  ? -12.894 15.190  -20.829 1.00 49.01  ? 63  TRP A CB  1 
ATOM   459   C CG  . TRP A 1 63  ? -12.105 15.264  -19.553 1.00 43.21  ? 63  TRP A CG  1 
ATOM   460   C CD1 . TRP A 1 63  ? -12.604 15.252  -18.283 1.00 42.34  ? 63  TRP A CD1 1 
ATOM   461   C CD2 . TRP A 1 63  ? -10.692 15.479  -19.423 1.00 42.59  ? 63  TRP A CD2 1 
ATOM   462   N NE1 . TRP A 1 63  ? -11.595 15.428  -17.376 1.00 40.14  ? 63  TRP A NE1 1 
ATOM   463   C CE2 . TRP A 1 63  ? -10.415 15.571  -18.042 1.00 37.01  ? 63  TRP A CE2 1 
ATOM   464   C CE3 . TRP A 1 63  ? -9.635  15.585  -20.331 1.00 43.43  ? 63  TRP A CE3 1 
ATOM   465   C CZ2 . TRP A 1 63  ? -9.125  15.752  -17.553 1.00 38.69  ? 63  TRP A CZ2 1 
ATOM   466   C CZ3 . TRP A 1 63  ? -8.363  15.767  -19.845 1.00 41.28  ? 63  TRP A CZ3 1 
ATOM   467   C CH2 . TRP A 1 63  ? -8.113  15.845  -18.471 1.00 38.56  ? 63  TRP A CH2 1 
ATOM   468   N N   . ALA A 1 64  ? -14.030 12.216  -20.633 1.00 59.22  ? 64  ALA A N   1 
ATOM   469   C CA  . ALA A 1 64  ? -14.292 10.988  -19.887 1.00 59.93  ? 64  ALA A CA  1 
ATOM   470   C C   . ALA A 1 64  ? -13.932 9.754   -20.723 1.00 58.55  ? 64  ALA A C   1 
ATOM   471   O O   . ALA A 1 64  ? -13.608 8.705   -20.174 1.00 57.95  ? 64  ALA A O   1 
ATOM   472   C CB  . ALA A 1 64  ? -15.730 10.941  -19.447 1.00 61.13  ? 64  ALA A CB  1 
ATOM   473   N N   . ALA A 1 65  ? -13.994 9.879   -22.044 1.00 58.70  ? 65  ALA A N   1 
ATOM   474   C CA  . ALA A 1 65  ? -13.736 8.733   -22.916 1.00 65.35  ? 65  ALA A CA  1 
ATOM   475   C C   . ALA A 1 65  ? -12.226 8.441   -23.001 1.00 62.72  ? 65  ALA A C   1 
ATOM   476   O O   . ALA A 1 65  ? -11.827 7.348   -23.384 1.00 70.85  ? 65  ALA A O   1 
ATOM   477   C CB  . ALA A 1 65  ? -14.334 8.976   -24.284 1.00 64.81  ? 65  ALA A CB  1 
ATOM   478   N N   . LEU A 1 66  ? -11.398 9.429   -22.649 1.00 58.75  ? 66  LEU A N   1 
ATOM   479   C CA  . LEU A 1 66  ? -9.949  9.260   -22.674 1.00 56.52  ? 66  LEU A CA  1 
ATOM   480   C C   . LEU A 1 66  ? -9.535  8.190   -21.656 1.00 58.17  ? 66  LEU A C   1 
ATOM   481   O O   . LEU A 1 66  ? -10.221 7.963   -20.663 1.00 54.90  ? 66  LEU A O   1 
ATOM   482   C CB  . LEU A 1 66  ? -9.256  10.586  -22.359 1.00 59.36  ? 66  LEU A CB  1 
ATOM   483   C CG  . LEU A 1 66  ? -9.381  11.699  -23.402 1.00 58.79  ? 66  LEU A CG  1 
ATOM   484   C CD1 . LEU A 1 66  ? -8.851  13.035  -22.821 1.00 58.69  ? 66  LEU A CD1 1 
ATOM   485   C CD2 . LEU A 1 66  ? -8.646  11.332  -24.685 1.00 58.11  ? 66  LEU A CD2 1 
ATOM   486   N N   . GLY A 1 67  ? -8.342  7.631   -21.861 1.00 59.11  ? 67  GLY A N   1 
ATOM   487   C CA  . GLY A 1 67  ? -7.755  6.708   -20.918 1.00 58.16  ? 67  GLY A CA  1 
ATOM   488   C C   . GLY A 1 67  ? -7.352  7.414   -19.617 1.00 60.55  ? 67  GLY A C   1 
ATOM   489   O O   . GLY A 1 67  ? -7.139  8.631   -19.597 1.00 53.86  ? 67  GLY A O   1 
ATOM   490   N N   . PRO A 1 68  ? -7.224  6.661   -18.498 1.00 56.32  ? 68  PRO A N   1 
ATOM   491   C CA  . PRO A 1 68  ? -6.771  7.230   -17.224 1.00 54.38  ? 68  PRO A CA  1 
ATOM   492   C C   . PRO A 1 68  ? -5.425  7.960   -17.293 1.00 53.43  ? 68  PRO A C   1 
ATOM   493   O O   . PRO A 1 68  ? -5.234  8.965   -16.619 1.00 54.10  ? 68  PRO A O   1 
ATOM   494   C CB  . PRO A 1 68  ? -6.709  6.008   -16.312 1.00 51.94  ? 68  PRO A CB  1 
ATOM   495   C CG  . PRO A 1 68  ? -7.702  5.033   -16.926 1.00 55.18  ? 68  PRO A CG  1 
ATOM   496   C CD  . PRO A 1 68  ? -7.560  5.235   -18.402 1.00 55.39  ? 68  PRO A CD  1 
ATOM   497   N N   . SER A 1 69  ? -4.501  7.448   -18.116 1.00 53.30  ? 69  SER A N   1 
ATOM   498   C CA  . SER A 1 69  ? -3.146  8.003   -18.200 1.00 52.75  ? 69  SER A CA  1 
ATOM   499   C C   . SER A 1 69  ? -3.167  9.423   -18.782 1.00 51.55  ? 69  SER A C   1 
ATOM   500   O O   . SER A 1 69  ? -2.425  10.284  -18.324 1.00 48.79  ? 69  SER A O   1 
ATOM   501   C CB  . SER A 1 69  ? -2.248  7.108   -18.989 1.00 48.68  ? 69  SER A CB  1 
ATOM   502   O OG  . SER A 1 69  ? -1.934  5.946   -18.238 1.00 52.68  ? 69  SER A OG  1 
ATOM   503   N N   . ALA A 1 70  ? -4.037  9.645   -19.786 1.00 49.54  ? 70  ALA A N   1 
ATOM   504   C CA  . ALA A 1 70  ? -4.168  10.933  -20.438 1.00 45.99  ? 70  ALA A CA  1 
ATOM   505   C C   . ALA A 1 70  ? -4.633  11.993  -19.435 1.00 49.56  ? 70  ALA A C   1 
ATOM   506   O O   . ALA A 1 70  ? -4.055  13.067  -19.363 1.00 56.06  ? 70  ALA A O   1 
ATOM   507   C CB  . ALA A 1 70  ? -5.129  10.820  -21.609 1.00 50.20  ? 70  ALA A CB  1 
ATOM   508   N N   . ARG A 1 71  ? -5.686  11.680  -18.674 1.00 47.43  ? 71  ARG A N   1 
ATOM   509   C CA  . ARG A 1 71  ? -6.244  12.624  -17.720 1.00 50.03  ? 71  ARG A CA  1 
ATOM   510   C C   . ARG A 1 71  ? -5.253  12.831  -16.579 1.00 49.91  ? 71  ARG A C   1 
ATOM   511   O O   . ARG A 1 71  ? -5.110  13.940  -16.076 1.00 56.51  ? 71  ARG A O   1 
ATOM   512   C CB  . ARG A 1 71  ? -7.620  12.175  -17.190 1.00 54.68  ? 71  ARG A CB  1 
ATOM   513   C CG  . ARG A 1 71  ? -8.783  12.379  -18.157 1.00 51.49  ? 71  ARG A CG  1 
ATOM   514   C CD  . ARG A 1 71  ? -10.113 11.887  -17.578 1.00 50.71  ? 71  ARG A CD  1 
ATOM   515   N NE  . ARG A 1 71  ? -10.370 10.479  -17.938 1.00 54.57  ? 71  ARG A NE  1 
ATOM   516   C CZ  . ARG A 1 71  ? -10.403 9.480   -17.091 1.00 52.76  ? 71  ARG A CZ  1 
ATOM   517   N NH1 . ARG A 1 71  ? -10.273 9.711   -15.795 1.00 57.10  ? 71  ARG A NH1 1 
ATOM   518   N NH2 . ARG A 1 71  ? -10.571 8.250   -17.531 1.00 59.07  ? 71  ARG A NH2 1 
ATOM   519   N N   . ALA A 1 72  ? -4.550  11.770  -16.191 1.00 53.67  ? 72  ALA A N   1 
ATOM   520   C CA  . ALA A 1 72  ? -3.572  11.874  -15.108 1.00 59.10  ? 72  ALA A CA  1 
ATOM   521   C C   . ALA A 1 72  ? -2.415  12.778  -15.536 1.00 52.08  ? 72  ALA A C   1 
ATOM   522   O O   . ALA A 1 72  ? -1.856  13.496  -14.721 1.00 50.26  ? 72  ALA A O   1 
ATOM   523   C CB  . ALA A 1 72  ? -3.074  10.491  -14.695 1.00 58.35  ? 72  ALA A CB  1 
ATOM   524   N N   . ALA A 1 73  ? -2.055  12.712  -16.817 1.00 47.59  ? 73  ALA A N   1 
ATOM   525   C CA  . ALA A 1 73  ? -0.902  13.441  -17.328 1.00 50.68  ? 73  ALA A CA  1 
ATOM   526   C C   . ALA A 1 73  ? -1.121  14.957  -17.187 1.00 53.29  ? 73  ALA A C   1 
ATOM   527   O O   . ALA A 1 73  ? -0.186  15.695  -16.886 1.00 48.89  ? 73  ALA A O   1 
ATOM   528   C CB  . ALA A 1 73  ? -0.636  13.043  -18.776 1.00 49.18  ? 73  ALA A CB  1 
ATOM   529   N N   . VAL A 1 74  ? -2.361  15.410  -17.413 1.00 51.91  ? 74  VAL A N   1 
ATOM   530   C CA  . VAL A 1 74  ? -2.697  16.816  -17.252 1.00 53.86  ? 74  VAL A CA  1 
ATOM   531   C C   . VAL A 1 74  ? -2.422  17.229  -15.804 1.00 54.97  ? 74  VAL A C   1 
ATOM   532   O O   . VAL A 1 74  ? -1.828  18.278  -15.560 1.00 60.30  ? 74  VAL A O   1 
ATOM   533   C CB  . VAL A 1 74  ? -4.157  17.107  -17.653 1.00 55.95  ? 74  VAL A CB  1 
ATOM   534   C CG1 . VAL A 1 74  ? -4.613  18.495  -17.184 1.00 53.85  ? 74  VAL A CG1 1 
ATOM   535   C CG2 . VAL A 1 74  ? -4.376  16.942  -19.165 1.00 51.93  ? 74  VAL A CG2 1 
ATOM   536   N N   . LEU A 1 75  ? -2.875  16.399  -14.848 1.00 53.92  ? 75  LEU A N   1 
ATOM   537   C CA  . LEU A 1 75  ? -2.751  16.716  -13.427 1.00 52.57  ? 75  LEU A CA  1 
ATOM   538   C C   . LEU A 1 75  ? -1.276  16.834  -13.053 1.00 55.66  ? 75  LEU A C   1 
ATOM   539   O O   . LEU A 1 75  ? -0.918  17.658  -12.208 1.00 52.50  ? 75  LEU A O   1 
ATOM   540   C CB  . LEU A 1 75  ? -3.456  15.673  -12.545 1.00 50.24  ? 75  LEU A CB  1 
ATOM   541   C CG  . LEU A 1 75  ? -4.896  15.996  -12.114 1.00 51.46  ? 75  LEU A CG  1 
ATOM   542   C CD1 . LEU A 1 75  ? -4.945  17.290  -11.309 1.00 54.16  ? 75  LEU A CD1 1 
ATOM   543   C CD2 . LEU A 1 75  ? -5.848  16.062  -13.319 1.00 49.04  ? 75  LEU A CD2 1 
ATOM   544   N N   . TYR A 1 76  ? -0.432  15.959  -13.635 1.00 52.14  ? 76  TYR A N   1 
ATOM   545   C CA  . TYR A 1 76  ? 0.989   15.948  -13.309 1.00 55.39  ? 76  TYR A CA  1 
ATOM   546   C C   . TYR A 1 76  ? 1.631   17.263  -13.776 1.00 55.09  ? 76  TYR A C   1 
ATOM   547   O O   . TYR A 1 76  ? 2.474   17.830  -13.079 1.00 54.71  ? 76  TYR A O   1 
ATOM   548   C CB  . TYR A 1 76  ? 1.689   14.735  -13.930 1.00 48.44  ? 76  TYR A CB  1 
ATOM   549   C CG  . TYR A 1 76  ? 1.570   13.446  -13.134 1.00 49.42  ? 76  TYR A CG  1 
ATOM   550   C CD1 . TYR A 1 76  ? 1.957   13.379  -11.794 1.00 48.44  ? 76  TYR A CD1 1 
ATOM   551   C CD2 . TYR A 1 76  ? 1.078   12.290  -13.727 1.00 49.29  ? 76  TYR A CD2 1 
ATOM   552   C CE1 . TYR A 1 76  ? 1.857   12.194  -11.075 1.00 45.80  ? 76  TYR A CE1 1 
ATOM   553   C CE2 . TYR A 1 76  ? 0.961   11.108  -13.019 1.00 49.01  ? 76  TYR A CE2 1 
ATOM   554   C CZ  . TYR A 1 76  ? 1.346   11.057  -11.688 1.00 49.44  ? 76  TYR A CZ  1 
ATOM   555   O OH  . TYR A 1 76  ? 1.220   9.875   -10.995 1.00 54.42  ? 76  TYR A OH  1 
ATOM   556   N N   . LYS A 1 77  ? 1.237   17.726  -14.965 1.00 53.26  ? 77  LYS A N   1 
ATOM   557   C CA  . LYS A 1 77  ? 1.776   18.957  -15.525 1.00 61.00  ? 77  LYS A CA  1 
ATOM   558   C C   . LYS A 1 77  ? 1.415   20.150  -14.632 1.00 56.74  ? 77  LYS A C   1 
ATOM   559   O O   . LYS A 1 77  ? 2.200   21.073  -14.505 1.00 58.03  ? 77  LYS A O   1 
ATOM   560   C CB  . LYS A 1 77  ? 1.278   19.197  -16.953 1.00 61.66  ? 77  LYS A CB  1 
ATOM   561   C CG  . LYS A 1 77  ? 2.239   18.769  -18.047 1.00 66.02  ? 77  LYS A CG  1 
ATOM   562   C CD  . LYS A 1 77  ? 1.590   18.643  -19.421 1.00 73.35  ? 77  LYS A CD  1 
ATOM   563   C CE  . LYS A 1 77  ? 0.649   17.467  -19.500 1.00 83.52  ? 77  LYS A CE  1 
ATOM   564   N NZ  . LYS A 1 77  ? -0.044  17.362  -20.792 1.00 85.29  ? 77  LYS A NZ  1 
ATOM   565   N N   . ALA A 1 78  ? 0.214   20.128  -14.038 1.00 55.24  ? 78  ALA A N   1 
ATOM   566   C CA  . ALA A 1 78  ? -0.246  21.227  -13.194 1.00 49.67  ? 78  ALA A CA  1 
ATOM   567   C C   . ALA A 1 78  ? 0.636   21.336  -11.959 1.00 50.47  ? 78  ALA A C   1 
ATOM   568   O O   . ALA A 1 78  ? 0.874   22.431  -11.458 1.00 55.77  ? 78  ALA A O   1 
ATOM   569   C CB  . ALA A 1 78  ? -1.704  21.030  -12.810 1.00 52.41  ? 78  ALA A CB  1 
ATOM   570   N N   . VAL A 1 79  ? 1.121   20.199  -11.472 1.00 51.53  ? 79  VAL A N   1 
ATOM   571   C CA  . VAL A 1 79  ? 2.006   20.190  -10.322 1.00 53.56  ? 79  VAL A CA  1 
ATOM   572   C C   . VAL A 1 79  ? 3.300   20.954  -10.671 1.00 55.13  ? 79  VAL A C   1 
ATOM   573   O O   . VAL A 1 79  ? 3.810   21.711  -9.854  1.00 58.13  ? 79  VAL A O   1 
ATOM   574   C CB  . VAL A 1 79  ? 2.299   18.755  -9.844  1.00 52.72  ? 79  VAL A CB  1 
ATOM   575   C CG1 . VAL A 1 79  ? 3.257   18.733  -8.654  1.00 54.80  ? 79  VAL A CG1 1 
ATOM   576   C CG2 . VAL A 1 79  ? 1.019   17.998  -9.503  1.00 55.41  ? 79  VAL A CG2 1 
ATOM   577   N N   . GLU A 1 80  ? 3.809   20.755  -11.895 1.00 60.67  ? 80  GLU A N   1 
ATOM   578   C CA  . GLU A 1 80  ? 5.055   21.387  -12.329 1.00 71.11  ? 80  GLU A CA  1 
ATOM   579   C C   . GLU A 1 80  ? 4.873   22.906  -12.381 1.00 68.34  ? 80  GLU A C   1 
ATOM   580   O O   . GLU A 1 80  ? 5.772   23.649  -11.990 1.00 61.55  ? 80  GLU A O   1 
ATOM   581   C CB  . GLU A 1 80  ? 5.512   20.859  -13.690 1.00 76.92  ? 80  GLU A CB  1 
ATOM   582   C CG  . GLU A 1 80  ? 5.852   19.371  -13.672 1.00 86.95  ? 80  GLU A CG  1 
ATOM   583   C CD  . GLU A 1 80  ? 6.037   18.746  -15.042 1.00 99.46  ? 80  GLU A CD  1 
ATOM   584   O OE1 . GLU A 1 80  ? 6.775   19.336  -15.858 1.00 103.89 ? 80  GLU A OE1 1 
ATOM   585   O OE2 . GLU A 1 80  ? 5.457   17.658  -15.291 1.00 110.22 ? 80  GLU A OE2 1 
ATOM   586   N N   . VAL A 1 81  ? 3.686   23.347  -12.834 1.00 61.16  ? 81  VAL A N   1 
ATOM   587   C CA  . VAL A 1 81  ? 3.353   24.770  -12.884 1.00 62.95  ? 81  VAL A CA  1 
ATOM   588   C C   . VAL A 1 81  ? 3.335   25.352  -11.463 1.00 60.86  ? 81  VAL A C   1 
ATOM   589   O O   . VAL A 1 81  ? 3.794   26.451  -11.256 1.00 60.27  ? 81  VAL A O   1 
ATOM   590   C CB  . VAL A 1 81  ? 2.015   25.009  -13.605 1.00 60.76  ? 81  VAL A CB  1 
ATOM   591   C CG1 . VAL A 1 81  ? 1.614   26.489  -13.613 1.00 57.20  ? 81  VAL A CG1 1 
ATOM   592   C CG2 . VAL A 1 81  ? 2.046   24.454  -15.016 1.00 58.25  ? 81  VAL A CG2 1 
ATOM   593   N N   . PHE A 1 82  ? 2.806   24.590  -10.491 1.00 69.26  ? 82  PHE A N   1 
ATOM   594   C CA  . PHE A 1 82  ? 2.700   25.063  -9.109  1.00 65.20  ? 82  PHE A CA  1 
ATOM   595   C C   . PHE A 1 82  ? 4.092   25.354  -8.537  1.00 61.86  ? 82  PHE A C   1 
ATOM   596   O O   . PHE A 1 82  ? 4.261   26.331  -7.832  1.00 59.18  ? 82  PHE A O   1 
ATOM   597   C CB  . PHE A 1 82  ? 1.962   24.064  -8.219  1.00 56.90  ? 82  PHE A CB  1 
ATOM   598   C CG  . PHE A 1 82  ? 0.494   24.377  -7.990  1.00 49.83  ? 82  PHE A CG  1 
ATOM   599   C CD1 . PHE A 1 82  ? -0.462  24.040  -8.944  1.00 47.29  ? 82  PHE A CD1 1 
ATOM   600   C CD2 . PHE A 1 82  ? 0.066   24.971  -6.800  1.00 48.78  ? 82  PHE A CD2 1 
ATOM   601   C CE1 . PHE A 1 82  ? -1.813  24.280  -8.714  1.00 45.77  ? 82  PHE A CE1 1 
ATOM   602   C CE2 . PHE A 1 82  ? -1.276  25.249  -6.588  1.00 47.84  ? 82  PHE A CE2 1 
ATOM   603   C CZ  . PHE A 1 82  ? -2.217  24.894  -7.542  1.00 52.02  ? 82  PHE A CZ  1 
ATOM   604   N N   . ASP A 1 83  ? 5.062   24.469  -8.811  1.00 64.71  ? 83  ASP A N   1 
ATOM   605   C CA  . ASP A 1 83  ? 6.453   24.721  -8.464  1.00 68.27  ? 83  ASP A CA  1 
ATOM   606   C C   . ASP A 1 83  ? 6.982   25.866  -9.316  1.00 71.08  ? 83  ASP A C   1 
ATOM   607   O O   . ASP A 1 83  ? 7.778   26.680  -8.851  1.00 70.73  ? 83  ASP A O   1 
ATOM   608   C CB  . ASP A 1 83  ? 7.307   23.491  -8.682  1.00 64.70  ? 83  ASP A CB  1 
ATOM   609   C CG  . ASP A 1 83  ? 6.832   22.253  -7.960  1.00 65.84  ? 83  ASP A CG  1 
ATOM   610   O OD1 . ASP A 1 83  ? 6.032   22.403  -7.000  1.00 70.38  ? 83  ASP A OD1 1 
ATOM   611   O OD2 . ASP A 1 83  ? 7.224   21.157  -8.381  1.00 60.59  ? 83  ASP A OD2 1 
ATOM   612   N N   . ARG A 1 84  ? 6.510   25.921  -10.560 1.00 72.58  ? 84  ARG A N   1 
ATOM   613   C CA  . ARG A 1 84  ? 7.101   26.779  -11.572 1.00 69.61  ? 84  ARG A CA  1 
ATOM   614   C C   . ARG A 1 84  ? 6.814   28.239  -11.242 1.00 72.43  ? 84  ARG A C   1 
ATOM   615   O O   . ARG A 1 84  ? 7.684   29.096  -11.391 1.00 74.24  ? 84  ARG A O   1 
ATOM   616   C CB  . ARG A 1 84  ? 6.567   26.430  -12.962 1.00 50.00  ? 84  ARG A CB  1 
ATOM   617   C CG  . ARG A 1 84  ? 6.703   27.552  -13.979 1.00 50.00  ? 84  ARG A CG  1 
ATOM   618   C CD  . ARG A 1 84  ? 6.129   27.222  -15.348 1.00 50.00  ? 84  ARG A CD  1 
ATOM   619   N NE  . ARG A 1 84  ? 6.345   28.302  -16.307 1.00 50.00  ? 84  ARG A NE  1 
ATOM   620   C CZ  . ARG A 1 84  ? 6.046   28.225  -17.595 1.00 50.00  ? 84  ARG A CZ  1 
ATOM   621   N NH1 . ARG A 1 84  ? 5.511   27.115  -18.089 1.00 50.00  ? 84  ARG A NH1 1 
ATOM   622   N NH2 . ARG A 1 84  ? 6.278   29.257  -18.396 1.00 50.00  ? 84  ARG A NH2 1 
ATOM   623   N N   . ARG A 1 85  ? 5.573   28.495  -10.787 1.00 65.88  ? 85  ARG A N   1 
ATOM   624   C CA  . ARG A 1 85  ? 5.084   29.830  -10.495 1.00 60.56  ? 85  ARG A CA  1 
ATOM   625   C C   . ARG A 1 85  ? 4.797   29.967  -8.989  1.00 56.77  ? 85  ARG A C   1 
ATOM   626   O O   . ARG A 1 85  ? 3.898   30.707  -8.599  1.00 54.47  ? 85  ARG A O   1 
ATOM   627   C CB  . ARG A 1 85  ? 3.794   30.095  -11.277 1.00 58.45  ? 85  ARG A CB  1 
ATOM   628   C CG  . ARG A 1 85  ? 3.847   29.733  -12.755 1.00 60.26  ? 85  ARG A CG  1 
ATOM   629   C CD  . ARG A 1 85  ? 2.530   30.101  -13.460 1.00 61.86  ? 85  ARG A CD  1 
ATOM   630   N NE  . ARG A 1 85  ? 2.660   30.151  -14.918 1.00 63.82  ? 85  ARG A NE  1 
ATOM   631   C CZ  . ARG A 1 85  ? 3.156   31.176  -15.617 1.00 65.35  ? 85  ARG A CZ  1 
ATOM   632   N NH1 . ARG A 1 85  ? 3.625   32.244  -14.996 1.00 66.47  ? 85  ARG A NH1 1 
ATOM   633   N NH2 . ARG A 1 85  ? 3.170   31.125  -16.942 1.00 59.97  ? 85  ARG A NH2 1 
ATOM   634   N N   . HIS A 1 86  ? 5.611   29.286  -8.156  1.00 51.27  ? 86  HIS A N   1 
ATOM   635   C CA  . HIS A 1 86  ? 5.436   29.280  -6.711  1.00 54.68  ? 86  HIS A CA  1 
ATOM   636   C C   . HIS A 1 86  ? 5.224   30.712  -6.199  1.00 64.60  ? 86  HIS A C   1 
ATOM   637   O O   . HIS A 1 86  ? 4.205   30.998  -5.557  1.00 69.03  ? 86  HIS A O   1 
ATOM   638   C CB  . HIS A 1 86  ? 6.623   28.581  -6.045  1.00 56.54  ? 86  HIS A CB  1 
ATOM   639   C CG  . HIS A 1 86  ? 6.521   28.460  -4.561  1.00 60.01  ? 86  HIS A CG  1 
ATOM   640   N ND1 . HIS A 1 86  ? 7.414   27.697  -3.830  1.00 66.65  ? 86  HIS A ND1 1 
ATOM   641   C CD2 . HIS A 1 86  ? 5.685   29.018  -3.661  1.00 58.11  ? 86  HIS A CD2 1 
ATOM   642   C CE1 . HIS A 1 86  ? 7.120   27.794  -2.536  1.00 61.65  ? 86  HIS A CE1 1 
ATOM   643   N NE2 . HIS A 1 86  ? 6.068   28.581  -2.411  1.00 62.29  ? 86  HIS A NE2 1 
ATOM   644   N N   . GLU A 1 87  ? 6.198   31.602  -6.483  1.00 72.71  ? 87  GLU A N   1 
ATOM   645   C CA  . GLU A 1 87  ? 6.188   32.966  -5.951  1.00 74.02  ? 87  GLU A CA  1 
ATOM   646   C C   . GLU A 1 87  ? 4.985   33.736  -6.502  1.00 68.00  ? 87  GLU A C   1 
ATOM   647   O O   . GLU A 1 87  ? 4.320   34.454  -5.759  1.00 70.14  ? 87  GLU A O   1 
ATOM   648   C CB  . GLU A 1 87  ? 7.495   33.693  -6.272  1.00 77.52  ? 87  GLU A CB  1 
ATOM   649   C CG  . GLU A 1 87  ? 7.506   35.163  -5.841  1.00 83.04  ? 87  GLU A CG  1 
ATOM   650   C CD  . GLU A 1 87  ? 7.085   35.409  -4.402  1.00 81.67  ? 87  GLU A CD  1 
ATOM   651   O OE1 . GLU A 1 87  ? 7.683   34.783  -3.517  1.00 81.97  ? 87  GLU A OE1 1 
ATOM   652   O OE2 . GLU A 1 87  ? 6.157   36.214  -4.171  1.00 79.88  ? 87  GLU A OE2 1 
ATOM   653   N N   . GLU A 1 88  ? 4.706   33.569  -7.805  1.00 65.36  ? 88  GLU A N   1 
ATOM   654   C CA  . GLU A 1 88  ? 3.619   34.293  -8.457  1.00 65.35  ? 88  GLU A CA  1 
ATOM   655   C C   . GLU A 1 88  ? 2.288   33.965  -7.763  1.00 70.72  ? 88  GLU A C   1 
ATOM   656   O O   . GLU A 1 88  ? 1.507   34.870  -7.464  1.00 68.79  ? 88  GLU A O   1 
ATOM   657   C CB  . GLU A 1 88  ? 3.583   33.987  -9.957  1.00 63.72  ? 88  GLU A CB  1 
ATOM   658   C CG  . GLU A 1 88  ? 2.279   34.412  -10.638 1.00 62.24  ? 88  GLU A CG  1 
ATOM   659   C CD  . GLU A 1 88  ? 2.308   34.288  -12.164 1.00 63.60  ? 88  GLU A CD  1 
ATOM   660   O OE1 . GLU A 1 88  ? 3.211   33.602  -12.710 1.00 62.33  ? 88  GLU A OE1 1 
ATOM   661   O OE2 . GLU A 1 88  ? 1.465   34.920  -12.810 1.00 62.24  ? 88  GLU A OE2 1 
ATOM   662   N N   . ILE A 1 89  ? 2.045   32.664  -7.512  1.00 75.43  ? 89  ILE A N   1 
ATOM   663   C CA  . ILE A 1 89  ? 0.793   32.208  -6.904  1.00 77.73  ? 89  ILE A CA  1 
ATOM   664   C C   . ILE A 1 89  ? 0.705   32.743  -5.473  1.00 71.54  ? 89  ILE A C   1 
ATOM   665   O O   . ILE A 1 89  ? -0.328  33.279  -5.076  1.00 63.34  ? 89  ILE A O   1 
ATOM   666   C CB  . ILE A 1 89  ? 0.672   30.665  -6.950  1.00 79.23  ? 89  ILE A CB  1 
ATOM   667   C CG1 . ILE A 1 89  ? 0.626   30.147  -8.374  1.00 81.87  ? 89  ILE A CG1 1 
ATOM   668   C CG2 . ILE A 1 89  ? -0.536  30.175  -6.150  1.00 80.46  ? 89  ILE A CG2 1 
ATOM   669   C CD1 . ILE A 1 89  ? 1.174   28.744  -8.531  1.00 80.49  ? 89  ILE A CD1 1 
ATOM   670   N N   . VAL A 1 90  ? 1.791   32.580  -4.704  1.00 72.86  ? 90  VAL A N   1 
ATOM   671   C CA  . VAL A 1 90  ? 1.819   33.027  -3.314  1.00 78.60  ? 90  VAL A CA  1 
ATOM   672   C C   . VAL A 1 90  ? 1.533   34.536  -3.253  1.00 85.03  ? 90  VAL A C   1 
ATOM   673   O O   . VAL A 1 90  ? 0.821   35.000  -2.349  1.00 72.44  ? 90  VAL A O   1 
ATOM   674   C CB  . VAL A 1 90  ? 3.157   32.686  -2.635  1.00 81.26  ? 90  VAL A CB  1 
ATOM   675   C CG1 . VAL A 1 90  ? 3.399   33.540  -1.388  1.00 78.63  ? 90  VAL A CG1 1 
ATOM   676   C CG2 . VAL A 1 90  ? 3.253   31.202  -2.303  1.00 85.22  ? 90  VAL A CG2 1 
ATOM   677   N N   . ASP A 1 91  ? 2.100   35.295  -4.220  1.00 84.47  ? 91  ASP A N   1 
ATOM   678   C CA  . ASP A 1 91  ? 1.952   36.747  -4.254  1.00 82.43  ? 91  ASP A CA  1 
ATOM   679   C C   . ASP A 1 91  ? 0.476   37.123  -4.435  1.00 73.03  ? 91  ASP A C   1 
ATOM   680   O O   . ASP A 1 91  ? -0.025  38.022  -3.757  1.00 58.75  ? 91  ASP A O   1 
ATOM   681   C CB  . ASP A 1 91  ? 2.824   37.374  -5.326  1.00 91.46  ? 91  ASP A CB  1 
ATOM   682   C CG  . ASP A 1 91  ? 2.874   38.894  -5.304  1.00 97.19  ? 91  ASP A CG  1 
ATOM   683   O OD1 . ASP A 1 91  ? 3.514   39.457  -4.377  1.00 97.06  ? 91  ASP A OD1 1 
ATOM   684   O OD2 . ASP A 1 91  ? 2.230   39.503  -6.169  1.00 107.14 ? 91  ASP A OD2 1 
ATOM   685   N N   . TRP A 1 92  ? -0.215  36.415  -5.332  1.00 68.73  ? 92  TRP A N   1 
ATOM   686   C CA  . TRP A 1 92  ? -1.631  36.685  -5.592  1.00 81.42  ? 92  TRP A CA  1 
ATOM   687   C C   . TRP A 1 92  ? -2.495  36.446  -4.339  1.00 78.50  ? 92  TRP A C   1 
ATOM   688   O O   . TRP A 1 92  ? -3.448  37.180  -4.099  1.00 70.98  ? 92  TRP A O   1 
ATOM   689   C CB  . TRP A 1 92  ? -2.129  35.852  -6.780  1.00 87.09  ? 92  TRP A CB  1 
ATOM   690   C CG  . TRP A 1 92  ? -2.083  36.608  -8.075  1.00 88.30  ? 92  TRP A CG  1 
ATOM   691   C CD1 . TRP A 1 92  ? -1.226  36.425  -9.121  1.00 84.41  ? 92  TRP A CD1 1 
ATOM   692   C CD2 . TRP A 1 92  ? -2.893  37.747  -8.411  1.00 87.04  ? 92  TRP A CD2 1 
ATOM   693   N NE1 . TRP A 1 92  ? -1.481  37.344  -10.105 1.00 85.22  ? 92  TRP A NE1 1 
ATOM   694   C CE2 . TRP A 1 92  ? -2.490  38.175  -9.690  1.00 86.43  ? 92  TRP A CE2 1 
ATOM   695   C CE3 . TRP A 1 92  ? -3.924  38.436  -7.757  1.00 84.12  ? 92  TRP A CE3 1 
ATOM   696   C CZ2 . TRP A 1 92  ? -3.083  39.262  -10.324 1.00 90.47  ? 92  TRP A CZ2 1 
ATOM   697   C CZ3 . TRP A 1 92  ? -4.511  39.510  -8.388  1.00 83.68  ? 92  TRP A CZ3 1 
ATOM   698   C CH2 . TRP A 1 92  ? -4.093  39.917  -9.652  1.00 91.01  ? 92  TRP A CH2 1 
ATOM   699   N N   . ILE A 1 93  ? -2.152  35.417  -3.551  1.00 84.23  ? 93  ILE A N   1 
ATOM   700   C CA  . ILE A 1 93  ? -2.898  35.082  -2.340  1.00 80.05  ? 93  ILE A CA  1 
ATOM   701   C C   . ILE A 1 93  ? -2.769  36.235  -1.332  1.00 74.97  ? 93  ILE A C   1 
ATOM   702   O O   . ILE A 1 93  ? -3.766  36.660  -0.757  1.00 67.33  ? 93  ILE A O   1 
ATOM   703   C CB  . ILE A 1 93  ? -2.421  33.724  -1.750  1.00 78.90  ? 93  ILE A CB  1 
ATOM   704   C CG1 . ILE A 1 93  ? -2.853  32.539  -2.637  1.00 72.82  ? 93  ILE A CG1 1 
ATOM   705   C CG2 . ILE A 1 93  ? -2.894  33.539  -0.307  1.00 73.26  ? 93  ILE A CG2 1 
ATOM   706   C CD1 . ILE A 1 93  ? -2.253  31.214  -2.224  1.00 67.08  ? 93  ILE A CD1 1 
ATOM   707   N N   . ILE A 1 94  ? -1.521  36.709  -1.107  1.00 75.81  ? 94  ILE A N   1 
ATOM   708   C CA  . ILE A 1 94  ? -1.257  37.815  -0.181  1.00 79.80  ? 94  ILE A CA  1 
ATOM   709   C C   . ILE A 1 94  ? -2.012  39.046  -0.660  1.00 80.38  ? 94  ILE A C   1 
ATOM   710   O O   . ILE A 1 94  ? -2.693  39.700  0.128   1.00 71.62  ? 94  ILE A O   1 
ATOM   711   C CB  . ILE A 1 94  ? 0.256   38.106  -0.068  1.00 81.93  ? 94  ILE A CB  1 
ATOM   712   C CG1 . ILE A 1 94  ? 0.994   36.994  0.671   1.00 77.60  ? 94  ILE A CG1 1 
ATOM   713   C CG2 . ILE A 1 94  ? 0.509   39.476  0.582   1.00 84.50  ? 94  ILE A CG2 1 
ATOM   714   C CD1 . ILE A 1 94  ? 2.502   37.107  0.599   1.00 73.85  ? 94  ILE A CD1 1 
ATOM   715   N N   . ARG A 1 95  ? -1.867  39.332  -1.968  1.00 81.48  ? 95  ARG A N   1 
ATOM   716   C CA  . ARG A 1 95  ? -2.412  40.525  -2.613  1.00 87.94  ? 95  ARG A CA  1 
ATOM   717   C C   . ARG A 1 95  ? -3.945  40.560  -2.510  1.00 81.08  ? 95  ARG A C   1 
ATOM   718   O O   . ARG A 1 95  ? -4.514  41.550  -2.065  1.00 69.62  ? 95  ARG A O   1 
ATOM   719   C CB  . ARG A 1 95  ? -1.997  40.546  -4.093  1.00 100.55 ? 95  ARG A CB  1 
ATOM   720   C CG  . ARG A 1 95  ? -0.618  41.154  -4.389  1.00 99.01  ? 95  ARG A CG  1 
ATOM   721   C CD  . ARG A 1 95  ? -0.623  41.986  -5.700  1.00 111.98 ? 95  ARG A CD  1 
ATOM   722   N NE  . ARG A 1 95  ? -0.161  41.228  -6.880  1.00 110.34 ? 95  ARG A NE  1 
ATOM   723   C CZ  . ARG A 1 95  ? -0.451  41.516  -8.155  1.00 104.80 ? 95  ARG A CZ  1 
ATOM   724   N NH1 . ARG A 1 95  ? 0.015   40.762  -9.129  1.00 102.66 ? 95  ARG A NH1 1 
ATOM   725   N NH2 . ARG A 1 95  ? -1.214  42.542  -8.447  1.00 112.78 ? 95  ARG A NH2 1 
ATOM   726   N N   . GLU A 1 96  ? -4.607  39.507  -3.005  1.00 82.89  ? 96  GLU A N   1 
ATOM   727   C CA  . GLU A 1 96  ? -6.049  39.551  -3.205  1.00 81.86  ? 96  GLU A CA  1 
ATOM   728   C C   . GLU A 1 96  ? -6.765  39.371  -1.862  1.00 73.30  ? 96  GLU A C   1 
ATOM   729   O O   . GLU A 1 96  ? -7.587  40.188  -1.495  1.00 72.14  ? 96  GLU A O   1 
ATOM   730   C CB  . GLU A 1 96  ? -6.495  38.518  -4.237  1.00 82.37  ? 96  GLU A CB  1 
ATOM   731   C CG  . GLU A 1 96  ? -7.974  38.624  -4.596  1.00 87.27  ? 96  GLU A CG  1 
ATOM   732   C CD  . GLU A 1 96  ? -8.251  38.226  -6.026  1.00 94.86  ? 96  GLU A CD  1 
ATOM   733   O OE1 . GLU A 1 96  ? -7.812  38.987  -6.897  1.00 106.07 ? 96  GLU A OE1 1 
ATOM   734   O OE2 . GLU A 1 96  ? -8.833  37.142  -6.278  1.00 88.60  ? 96  GLU A OE2 1 
ATOM   735   N N   . SER A 1 97  ? -6.440  38.289  -1.142  1.00 77.15  ? 97  SER A N   1 
ATOM   736   C CA  . SER A 1 97  ? -7.221  37.875  0.030   1.00 79.72  ? 97  SER A CA  1 
ATOM   737   C C   . SER A 1 97  ? -6.730  38.587  1.295   1.00 71.97  ? 97  SER A C   1 
ATOM   738   O O   . SER A 1 97  ? -7.417  38.581  2.302   1.00 67.66  ? 97  SER A O   1 
ATOM   739   C CB  . SER A 1 97  ? -7.177  36.369  0.226   1.00 79.03  ? 97  SER A CB  1 
ATOM   740   O OG  . SER A 1 97  ? -6.193  36.011  1.192   1.00 73.72  ? 97  SER A OG  1 
ATOM   741   N N   . GLY A 1 98  ? -5.508  39.129  1.250   1.00 71.39  ? 98  GLY A N   1 
ATOM   742   C CA  . GLY A 1 98  ? -4.910  39.779  2.412   1.00 77.37  ? 98  GLY A CA  1 
ATOM   743   C C   . GLY A 1 98  ? -4.220  38.775  3.340   1.00 79.92  ? 98  GLY A C   1 
ATOM   744   O O   . GLY A 1 98  ? -3.880  39.106  4.472   1.00 75.51  ? 98  GLY A O   1 
ATOM   745   N N   . SER A 1 99  ? -3.992  37.558  2.832   1.00 82.08  ? 99  SER A N   1 
ATOM   746   C CA  . SER A 1 99  ? -3.362  36.506  3.608   1.00 71.82  ? 99  SER A CA  1 
ATOM   747   C C   . SER A 1 99  ? -1.902  36.869  3.882   1.00 66.51  ? 99  SER A C   1 
ATOM   748   O O   . SER A 1 99  ? -1.218  37.410  3.013   1.00 68.94  ? 99  SER A O   1 
ATOM   749   C CB  . SER A 1 99  ? -3.482  35.162  2.892   1.00 75.44  ? 99  SER A CB  1 
ATOM   750   O OG  . SER A 1 99  ? -2.494  34.232  3.345   1.00 86.81  ? 99  SER A OG  1 
ATOM   751   N N   . THR A 1 100 ? -1.423  36.514  5.077   1.00 60.80  ? 100 THR A N   1 
ATOM   752   C CA  . THR A 1 100 ? -0.029  36.710  5.433   1.00 64.94  ? 100 THR A CA  1 
ATOM   753   C C   . THR A 1 100 ? 0.852   35.783  4.593   1.00 69.71  ? 100 THR A C   1 
ATOM   754   O O   . THR A 1 100 ? 0.387   34.773  4.068   1.00 72.41  ? 100 THR A O   1 
ATOM   755   C CB  . THR A 1 100 ? 0.170   36.475  6.935   1.00 74.97  ? 100 THR A CB  1 
ATOM   756   O OG1 . THR A 1 100 ? -0.311  35.172  7.241   1.00 86.90  ? 100 THR A OG1 1 
ATOM   757   C CG2 . THR A 1 100 ? -0.580  37.483  7.787   1.00 77.11  ? 100 THR A CG2 1 
ATOM   758   N N   . ARG A 1 101 ? 2.139   36.143  4.480   1.00 69.21  ? 101 ARG A N   1 
ATOM   759   C CA  . ARG A 1 101 ? 3.091   35.367  3.697   1.00 74.42  ? 101 ARG A CA  1 
ATOM   760   C C   . ARG A 1 101 ? 3.225   33.968  4.293   1.00 72.13  ? 101 ARG A C   1 
ATOM   761   O O   . ARG A 1 101 ? 3.403   32.996  3.566   1.00 69.46  ? 101 ARG A O   1 
ATOM   762   C CB  . ARG A 1 101 ? 4.458   36.060  3.634   1.00 80.26  ? 101 ARG A CB  1 
ATOM   763   C CG  . ARG A 1 101 ? 5.476   35.379  2.722   1.00 84.44  ? 101 ARG A CG  1 
ATOM   764   C CD  . ARG A 1 101 ? 6.523   36.366  2.153   1.00 84.81  ? 101 ARG A CD  1 
ATOM   765   N NE  . ARG A 1 101 ? 6.030   37.137  0.994   1.00 83.99  ? 101 ARG A NE  1 
ATOM   766   C CZ  . ARG A 1 101 ? 6.036   36.712  -0.294  1.00 89.14  ? 101 ARG A CZ  1 
ATOM   767   N NH1 . ARG A 1 101 ? 6.586   35.555  -0.612  1.00 93.17  ? 101 ARG A NH1 1 
ATOM   768   N NH2 . ARG A 1 101 ? 5.505   37.460  -1.253  1.00 80.59  ? 101 ARG A NH2 1 
ATOM   769   N N   . LEU A 1 102 ? 3.133   33.881  5.623   1.00 77.68  ? 102 LEU A N   1 
ATOM   770   C CA  . LEU A 1 102 ? 3.222   32.606  6.320   1.00 77.67  ? 102 LEU A CA  1 
ATOM   771   C C   . LEU A 1 102 ? 2.039   31.721  5.904   1.00 76.09  ? 102 LEU A C   1 
ATOM   772   O O   . LEU A 1 102 ? 2.230   30.572  5.513   1.00 73.47  ? 102 LEU A O   1 
ATOM   773   C CB  . LEU A 1 102 ? 3.251   32.855  7.830   1.00 82.09  ? 102 LEU A CB  1 
ATOM   774   C CG  . LEU A 1 102 ? 3.997   31.813  8.679   1.00 87.53  ? 102 LEU A CG  1 
ATOM   775   C CD1 . LEU A 1 102 ? 5.515   32.075  8.710   1.00 83.42  ? 102 LEU A CD1 1 
ATOM   776   C CD2 . LEU A 1 102 ? 3.423   31.775  10.096  1.00 89.62  ? 102 LEU A CD2 1 
ATOM   777   N N   . LYS A 1 103 ? 0.824   32.296  5.965   1.00 68.75  ? 103 LYS A N   1 
ATOM   778   C CA  . LYS A 1 103 ? -0.415  31.580  5.676   1.00 66.39  ? 103 LYS A CA  1 
ATOM   779   C C   . LYS A 1 103 ? -0.523  31.293  4.167   1.00 63.58  ? 103 LYS A C   1 
ATOM   780   O O   . LYS A 1 103 ? -1.044  30.269  3.776   1.00 70.14  ? 103 LYS A O   1 
ATOM   781   C CB  . LYS A 1 103 ? -1.575  32.428  6.225   1.00 74.96  ? 103 LYS A CB  1 
ATOM   782   C CG  . LYS A 1 103 ? -2.981  31.868  6.096   1.00 82.99  ? 103 LYS A CG  1 
ATOM   783   C CD  . LYS A 1 103 ? -3.988  32.961  5.754   1.00 89.37  ? 103 LYS A CD  1 
ATOM   784   C CE  . LYS A 1 103 ? -5.351  32.454  5.378   1.00 96.87  ? 103 LYS A CE  1 
ATOM   785   N NZ  . LYS A 1 103 ? -6.336  32.669  6.446   1.00 96.53  ? 103 LYS A NZ  1 
ATOM   786   N N   . ALA A 1 104 ? -0.011  32.206  3.331   1.00 67.48  ? 104 ALA A N   1 
ATOM   787   C CA  . ALA A 1 104 ? -0.121  32.070  1.883   1.00 69.12  ? 104 ALA A CA  1 
ATOM   788   C C   . ALA A 1 104 ? 0.691   30.873  1.407   1.00 67.54  ? 104 ALA A C   1 
ATOM   789   O O   . ALA A 1 104 ? 0.255   30.142  0.533   1.00 62.99  ? 104 ALA A O   1 
ATOM   790   C CB  . ALA A 1 104 ? 0.332   33.351  1.192   1.00 70.89  ? 104 ALA A CB  1 
ATOM   791   N N   . GLU A 1 105 ? 1.883   30.701  1.984   1.00 75.00  ? 105 GLU A N   1 
ATOM   792   C CA  . GLU A 1 105 ? 2.769   29.599  1.626   1.00 76.82  ? 105 GLU A CA  1 
ATOM   793   C C   . GLU A 1 105 ? 2.108   28.257  1.977   1.00 78.96  ? 105 GLU A C   1 
ATOM   794   O O   . GLU A 1 105 ? 2.209   27.298  1.210   1.00 79.41  ? 105 GLU A O   1 
ATOM   795   C CB  . GLU A 1 105 ? 4.126   29.738  2.325   1.00 73.00  ? 105 GLU A CB  1 
ATOM   796   C CG  . GLU A 1 105 ? 5.045   30.761  1.669   1.00 74.59  ? 105 GLU A CG  1 
ATOM   797   C CD  . GLU A 1 105 ? 5.733   30.263  0.414   1.00 82.19  ? 105 GLU A CD  1 
ATOM   798   O OE1 . GLU A 1 105 ? 6.287   31.107  -0.335  1.00 89.04  ? 105 GLU A OE1 1 
ATOM   799   O OE2 . GLU A 1 105 ? 5.731   29.023  0.188   1.00 82.65  ? 105 GLU A OE2 1 
ATOM   800   N N   . ILE A 1 106 ? 1.450   28.195  3.153   1.00 73.15  ? 106 ILE A N   1 
ATOM   801   C CA  . ILE A 1 106 ? 0.758   26.983  3.586   1.00 73.65  ? 106 ILE A CA  1 
ATOM   802   C C   . ILE A 1 106 ? -0.336  26.639  2.564   1.00 69.14  ? 106 ILE A C   1 
ATOM   803   O O   . ILE A 1 106 ? -0.457  25.485  2.148   1.00 61.94  ? 106 ILE A O   1 
ATOM   804   C CB  . ILE A 1 106 ? 0.197   27.129  5.025   1.00 71.02  ? 106 ILE A CB  1 
ATOM   805   C CG1 . ILE A 1 106 ? 1.155   26.547  6.071   1.00 68.00  ? 106 ILE A CG1 1 
ATOM   806   C CG2 . ILE A 1 106 ? -1.189  26.494  5.147   1.00 66.19  ? 106 ILE A CG2 1 
ATOM   807   C CD1 . ILE A 1 106 ? 2.501   27.232  6.139   1.00 68.27  ? 106 ILE A CD1 1 
ATOM   808   N N   . GLU A 1 107 ? -1.101  27.654  2.143   1.00 64.97  ? 107 GLU A N   1 
ATOM   809   C CA  . GLU A 1 107 ? -2.156  27.468  1.155   1.00 64.82  ? 107 GLU A CA  1 
ATOM   810   C C   . GLU A 1 107 ? -1.572  26.898  -0.145  1.00 60.98  ? 107 GLU A C   1 
ATOM   811   O O   . GLU A 1 107 ? -2.135  25.989  -0.737  1.00 62.57  ? 107 GLU A O   1 
ATOM   812   C CB  . GLU A 1 107 ? -2.885  28.788  0.914   1.00 67.52  ? 107 GLU A CB  1 
ATOM   813   C CG  . GLU A 1 107 ? -4.015  28.669  -0.099  1.00 70.95  ? 107 GLU A CG  1 
ATOM   814   C CD  . GLU A 1 107 ? -5.153  29.634  0.133   1.00 75.97  ? 107 GLU A CD  1 
ATOM   815   O OE1 . GLU A 1 107 ? -4.940  30.656  0.840   1.00 83.30  ? 107 GLU A OE1 1 
ATOM   816   O OE2 . GLU A 1 107 ? -6.274  29.338  -0.351  1.00 84.60  ? 107 GLU A OE2 1 
ATOM   817   N N   . TRP A 1 108 ? -0.455  27.461  -0.591  1.00 67.98  ? 108 TRP A N   1 
ATOM   818   C CA  . TRP A 1 108 ? 0.184   27.017  -1.819  1.00 67.46  ? 108 TRP A CA  1 
ATOM   819   C C   . TRP A 1 108 ? 0.559   25.528  -1.709  1.00 65.64  ? 108 TRP A C   1 
ATOM   820   O O   . TRP A 1 108 ? 0.268   24.742  -2.615  1.00 59.62  ? 108 TRP A O   1 
ATOM   821   C CB  . TRP A 1 108 ? 1.420   27.889  -2.132  1.00 63.13  ? 108 TRP A CB  1 
ATOM   822   C CG  . TRP A 1 108 ? 2.230   27.379  -3.298  1.00 58.02  ? 108 TRP A CG  1 
ATOM   823   C CD1 . TRP A 1 108 ? 2.035   27.657  -4.619  1.00 49.25  ? 108 TRP A CD1 1 
ATOM   824   C CD2 . TRP A 1 108 ? 3.304   26.419  -3.242  1.00 50.34  ? 108 TRP A CD2 1 
ATOM   825   N NE1 . TRP A 1 108 ? 2.935   26.970  -5.387  1.00 48.69  ? 108 TRP A NE1 1 
ATOM   826   C CE2 . TRP A 1 108 ? 3.717   26.188  -4.574  1.00 50.88  ? 108 TRP A CE2 1 
ATOM   827   C CE3 . TRP A 1 108 ? 3.946   25.735  -2.204  1.00 48.25  ? 108 TRP A CE3 1 
ATOM   828   C CZ2 . TRP A 1 108 ? 4.753   25.305  -4.891  1.00 52.87  ? 108 TRP A CZ2 1 
ATOM   829   C CZ3 . TRP A 1 108 ? 4.977   24.870  -2.513  1.00 50.45  ? 108 TRP A CZ3 1 
ATOM   830   C CH2 . TRP A 1 108 ? 5.368   24.651  -3.840  1.00 54.58  ? 108 TRP A CH2 1 
ATOM   831   N N   . GLY A 1 109 ? 1.231   25.171  -0.598  1.00 64.52  ? 109 GLY A N   1 
ATOM   832   C CA  . GLY A 1 109 ? 1.703   23.804  -0.352  1.00 61.80  ? 109 GLY A CA  1 
ATOM   833   C C   . GLY A 1 109 ? 0.548   22.797  -0.304  1.00 61.69  ? 109 GLY A C   1 
ATOM   834   O O   . GLY A 1 109 ? 0.624   21.725  -0.912  1.00 72.38  ? 109 GLY A O   1 
ATOM   835   N N   . ALA A 1 110 ? -0.525  23.167  0.397   1.00 56.36  ? 110 ALA A N   1 
ATOM   836   C CA  . ALA A 1 110 ? -1.718  22.340  0.495   1.00 57.66  ? 110 ALA A CA  1 
ATOM   837   C C   . ALA A 1 110 ? -2.319  22.080  -0.893  1.00 64.73  ? 110 ALA A C   1 
ATOM   838   O O   . ALA A 1 110 ? -2.650  20.935  -1.220  1.00 63.15  ? 110 ALA A O   1 
ATOM   839   C CB  . ALA A 1 110 ? -2.720  22.996  1.405   1.00 59.14  ? 110 ALA A CB  1 
ATOM   840   N N   . ALA A 1 111 ? -2.475  23.152  -1.695  1.00 58.72  ? 111 ALA A N   1 
ATOM   841   C CA  . ALA A 1 111 ? -3.089  23.051  -3.015  1.00 56.47  ? 111 ALA A CA  1 
ATOM   842   C C   . ALA A 1 111 ? -2.238  22.169  -3.940  1.00 54.38  ? 111 ALA A C   1 
ATOM   843   O O   . ALA A 1 111 ? -2.768  21.376  -4.715  1.00 53.00  ? 111 ALA A O   1 
ATOM   844   C CB  . ALA A 1 111 ? -3.285  24.435  -3.603  1.00 58.19  ? 111 ALA A CB  1 
ATOM   845   N N   . ARG A 1 112 ? -0.919  22.325  -3.858  1.00 48.62  ? 112 ARG A N   1 
ATOM   846   C CA  . ARG A 1 112 ? -0.022  21.551  -4.684  1.00 48.61  ? 112 ARG A CA  1 
ATOM   847   C C   . ARG A 1 112 ? -0.183  20.058  -4.353  1.00 49.64  ? 112 ARG A C   1 
ATOM   848   O O   . ARG A 1 112 ? -0.153  19.215  -5.246  1.00 43.28  ? 112 ARG A O   1 
ATOM   849   C CB  . ARG A 1 112 ? 1.419   22.011  -4.462  1.00 53.55  ? 112 ARG A CB  1 
ATOM   850   C CG  . ARG A 1 112 ? 2.440   21.300  -5.345  1.00 60.92  ? 112 ARG A CG  1 
ATOM   851   C CD  . ARG A 1 112 ? 3.804   21.272  -4.709  1.00 61.79  ? 112 ARG A CD  1 
ATOM   852   N NE  . ARG A 1 112 ? 4.744   20.478  -5.499  1.00 65.31  ? 112 ARG A NE  1 
ATOM   853   C CZ  . ARG A 1 112 ? 5.091   19.224  -5.223  1.00 63.09  ? 112 ARG A CZ  1 
ATOM   854   N NH1 . ARG A 1 112 ? 4.542   18.594  -4.203  1.00 64.57  ? 112 ARG A NH1 1 
ATOM   855   N NH2 . ARG A 1 112 ? 5.982   18.605  -5.975  1.00 60.97  ? 112 ARG A NH2 1 
ATOM   856   N N   . ALA A 1 113 ? -0.343  19.750  -3.057  1.00 47.87  ? 113 ALA A N   1 
ATOM   857   C CA  . ALA A 1 113 ? -0.469  18.373  -2.603  1.00 48.95  ? 113 ALA A CA  1 
ATOM   858   C C   . ALA A 1 113 ? -1.778  17.757  -3.117  1.00 53.59  ? 113 ALA A C   1 
ATOM   859   O O   . ALA A 1 113 ? -1.798  16.595  -3.509  1.00 55.99  ? 113 ALA A O   1 
ATOM   860   C CB  . ALA A 1 113 ? -0.378  18.313  -1.093  1.00 50.75  ? 113 ALA A CB  1 
ATOM   861   N N   . ILE A 1 114 ? -2.865  18.549  -3.116  1.00 52.64  ? 114 ILE A N   1 
ATOM   862   C CA  . ILE A 1 114 ? -4.144  18.101  -3.646  1.00 47.19  ? 114 ILE A CA  1 
ATOM   863   C C   . ILE A 1 114 ? -3.939  17.692  -5.107  1.00 49.88  ? 114 ILE A C   1 
ATOM   864   O O   . ILE A 1 114 ? -4.412  16.630  -5.537  1.00 48.56  ? 114 ILE A O   1 
ATOM   865   C CB  . ILE A 1 114 ? -5.228  19.204  -3.514  1.00 53.80  ? 114 ILE A CB  1 
ATOM   866   C CG1 . ILE A 1 114 ? -5.542  19.567  -2.055  1.00 54.83  ? 114 ILE A CG1 1 
ATOM   867   C CG2 . ILE A 1 114 ? -6.497  18.817  -4.270  1.00 58.12  ? 114 ILE A CG2 1 
ATOM   868   C CD1 . ILE A 1 114 ? -6.201  18.460  -1.268  1.00 60.79  ? 114 ILE A CD1 1 
ATOM   869   N N   . THR A 1 115 ? -3.244  18.550  -5.876  1.00 48.02  ? 115 THR A N   1 
ATOM   870   C CA  . THR A 1 115 ? -3.118  18.339  -7.312  1.00 54.65  ? 115 THR A CA  1 
ATOM   871   C C   . THR A 1 115 ? -2.311  17.052  -7.569  1.00 53.71  ? 115 THR A C   1 
ATOM   872   O O   . THR A 1 115 ? -2.639  16.276  -8.453  1.00 50.83  ? 115 THR A O   1 
ATOM   873   C CB  . THR A 1 115 ? -2.470  19.555  -7.983  1.00 52.20  ? 115 THR A CB  1 
ATOM   874   O OG1 . THR A 1 115 ? -3.121  20.716  -7.490  1.00 57.27  ? 115 THR A OG1 1 
ATOM   875   C CG2 . THR A 1 115 ? -2.619  19.525  -9.487  1.00 48.37  ? 115 THR A CG2 1 
ATOM   876   N N   . LEU A 1 116 ? -1.239  16.862  -6.809  1.00 56.97  ? 116 LEU A N   1 
ATOM   877   C CA  . LEU A 1 116 ? -0.394  15.681  -6.950  1.00 60.43  ? 116 LEU A CA  1 
ATOM   878   C C   . LEU A 1 116 ? -1.184  14.419  -6.577  1.00 56.50  ? 116 LEU A C   1 
ATOM   879   O O   . LEU A 1 116 ? -1.083  13.395  -7.245  1.00 51.71  ? 116 LEU A O   1 
ATOM   880   C CB  . LEU A 1 116 ? 0.843   15.841  -6.075  1.00 58.24  ? 116 LEU A CB  1 
ATOM   881   C CG  . LEU A 1 116 ? 1.888   14.731  -6.191  1.00 61.53  ? 116 LEU A CG  1 
ATOM   882   C CD1 . LEU A 1 116 ? 2.310   14.496  -7.652  1.00 61.83  ? 116 LEU A CD1 1 
ATOM   883   C CD2 . LEU A 1 116 ? 3.102   15.057  -5.320  1.00 58.23  ? 116 LEU A CD2 1 
ATOM   884   N N   . GLU A 1 117 ? -1.955  14.513  -5.501  1.00 57.33  ? 117 GLU A N   1 
ATOM   885   C CA  . GLU A 1 117 ? -2.771  13.401  -5.005  1.00 62.47  ? 117 GLU A CA  1 
ATOM   886   C C   . GLU A 1 117 ? -3.668  12.884  -6.123  1.00 57.88  ? 117 GLU A C   1 
ATOM   887   O O   . GLU A 1 117 ? -3.818  11.681  -6.296  1.00 55.57  ? 117 GLU A O   1 
ATOM   888   C CB  . GLU A 1 117 ? -3.709  13.896  -3.907  1.00 79.37  ? 117 GLU A CB  1 
ATOM   889   C CG  . GLU A 1 117 ? -3.645  13.150  -2.583  1.00 93.92  ? 117 GLU A CG  1 
ATOM   890   C CD  . GLU A 1 117 ? -3.771  14.184  -1.461  1.00 128.69 ? 117 GLU A CD  1 
ATOM   891   O OE1 . GLU A 1 117 ? -4.736  15.012  -1.525  1.00 168.82 ? 117 GLU A OE1 1 
ATOM   892   O OE2 . GLU A 1 117 ? -2.820  14.291  -0.641  1.00 129.46 ? 117 GLU A OE2 1 
ATOM   893   N N   . SER A 1 118 ? -4.318  13.828  -6.832  1.00 52.17  ? 118 SER A N   1 
ATOM   894   C CA  . SER A 1 118 ? -5.443  13.534  -7.715  1.00 51.30  ? 118 SER A CA  1 
ATOM   895   C C   . SER A 1 118 ? -4.967  12.826  -8.996  1.00 49.04  ? 118 SER A C   1 
ATOM   896   O O   . SER A 1 118 ? -5.762  12.200  -9.694  1.00 47.47  ? 118 SER A O   1 
ATOM   897   C CB  . SER A 1 118 ? -6.202  14.807  -8.065  1.00 57.29  ? 118 SER A CB  1 
ATOM   898   O OG  . SER A 1 118 ? -6.585  15.547  -6.907  1.00 58.46  ? 118 SER A OG  1 
ATOM   899   N N   . ALA A 1 119 ? -3.677  12.963  -9.325  1.00 44.16  ? 119 ALA A N   1 
ATOM   900   C CA  . ALA A 1 119 ? -3.131  12.354  -10.537 1.00 44.06  ? 119 ALA A CA  1 
ATOM   901   C C   . ALA A 1 119 ? -3.241  10.817  -10.472 1.00 43.33  ? 119 ALA A C   1 
ATOM   902   O O   . ALA A 1 119 ? -3.287  10.147  -11.506 1.00 41.31  ? 119 ALA A O   1 
ATOM   903   C CB  . ALA A 1 119 ? -1.698  12.795  -10.733 1.00 47.09  ? 119 ALA A CB  1 
ATOM   904   N N   . SER A 1 120 ? -3.267  10.267  -9.255  1.00 41.56  ? 120 SER A N   1 
ATOM   905   C CA  . SER A 1 120 ? -3.348  8.820   -9.074  1.00 46.40  ? 120 SER A CA  1 
ATOM   906   C C   . SER A 1 120 ? -4.813  8.329   -9.116  1.00 52.84  ? 120 SER A C   1 
ATOM   907   O O   . SER A 1 120 ? -5.056  7.140   -9.176  1.00 59.51  ? 120 SER A O   1 
ATOM   908   C CB  . SER A 1 120 ? -2.705  8.423   -7.816  1.00 45.60  ? 120 SER A CB  1 
ATOM   909   O OG  . SER A 1 120 ? -3.526  8.775   -6.708  1.00 53.19  ? 120 SER A OG  1 
ATOM   910   N N   . PHE A 1 121 ? -5.786  9.251   -9.092  1.00 54.50  ? 121 PHE A N   1 
ATOM   911   C CA  . PHE A 1 121 ? -7.173  8.863   -8.871  1.00 47.46  ? 121 PHE A CA  1 
ATOM   912   C C   . PHE A 1 121 ? -7.727  8.132   -10.084 1.00 43.17  ? 121 PHE A C   1 
ATOM   913   O O   . PHE A 1 121 ? -8.430  7.147   -9.923  1.00 49.72  ? 121 PHE A O   1 
ATOM   914   C CB  . PHE A 1 121 ? -8.057  10.050  -8.512  1.00 45.80  ? 121 PHE A CB  1 
ATOM   915   C CG  . PHE A 1 121 ? -7.883  10.542  -7.096  1.00 42.33  ? 121 PHE A CG  1 
ATOM   916   C CD1 . PHE A 1 121 ? -7.059  9.873   -6.204  1.00 40.70  ? 121 PHE A CD1 1 
ATOM   917   C CD2 . PHE A 1 121 ? -8.561  11.666  -6.649  1.00 44.89  ? 121 PHE A CD2 1 
ATOM   918   C CE1 . PHE A 1 121 ? -6.910  10.322  -4.911  1.00 41.41  ? 121 PHE A CE1 1 
ATOM   919   C CE2 . PHE A 1 121 ? -8.396  12.118  -5.353  1.00 43.84  ? 121 PHE A CE2 1 
ATOM   920   C CZ  . PHE A 1 121 ? -7.571  11.448  -4.491  1.00 45.60  ? 121 PHE A CZ  1 
ATOM   921   N N   . PRO A 1 122 ? -7.506  8.611   -11.322 1.00 45.54  ? 122 PRO A N   1 
ATOM   922   C CA  . PRO A 1 122 ? -8.020  7.909   -12.504 1.00 51.82  ? 122 PRO A CA  1 
ATOM   923   C C   . PRO A 1 122 ? -7.755  6.392   -12.521 1.00 56.79  ? 122 PRO A C   1 
ATOM   924   O O   . PRO A 1 122 ? -8.589  5.631   -12.988 1.00 56.93  ? 122 PRO A O   1 
ATOM   925   C CB  . PRO A 1 122 ? -7.301  8.640   -13.677 1.00 48.18  ? 122 PRO A CB  1 
ATOM   926   C CG  . PRO A 1 122 ? -7.101  10.040  -13.153 1.00 44.73  ? 122 PRO A CG  1 
ATOM   927   C CD  . PRO A 1 122 ? -6.792  9.850   -11.661 1.00 44.72  ? 122 PRO A CD  1 
ATOM   928   N N   . ALA A 1 123 ? -6.585  5.966   -12.007 1.00 57.97  ? 123 ALA A N   1 
ATOM   929   C CA  . ALA A 1 123 ? -6.187  4.560   -12.079 1.00 60.71  ? 123 ALA A CA  1 
ATOM   930   C C   . ALA A 1 123 ? -6.986  3.712   -11.090 1.00 55.35  ? 123 ALA A C   1 
ATOM   931   O O   . ALA A 1 123 ? -7.178  2.529   -11.327 1.00 65.00  ? 123 ALA A O   1 
ATOM   932   C CB  . ALA A 1 123 ? -4.691  4.406   -11.844 1.00 62.09  ? 123 ALA A CB  1 
ATOM   933   N N   . ARG A 1 124 ? -7.459  4.314   -9.988  1.00 51.68  ? 124 ARG A N   1 
ATOM   934   C CA  . ARG A 1 124 ? -7.950  3.517   -8.855  1.00 50.80  ? 124 ARG A CA  1 
ATOM   935   C C   . ARG A 1 124 ? -9.452  3.215   -8.962  1.00 53.11  ? 124 ARG A C   1 
ATOM   936   O O   . ARG A 1 124 ? -9.967  2.388   -8.211  1.00 51.27  ? 124 ARG A O   1 
ATOM   937   C CB  . ARG A 1 124 ? -7.689  4.217   -7.541  1.00 52.05  ? 124 ARG A CB  1 
ATOM   938   C CG  . ARG A 1 124 ? -6.226  4.508   -7.307  1.00 52.50  ? 124 ARG A CG  1 
ATOM   939   C CD  . ARG A 1 124 ? -6.067  5.560   -6.277  1.00 54.94  ? 124 ARG A CD  1 
ATOM   940   N NE  . ARG A 1 124 ? -6.781  5.201   -5.051  1.00 55.93  ? 124 ARG A NE  1 
ATOM   941   C CZ  . ARG A 1 124 ? -6.679  5.877   -3.917  1.00 57.42  ? 124 ARG A CZ  1 
ATOM   942   N NH1 . ARG A 1 124 ? -5.728  6.781   -3.785  1.00 58.76  ? 124 ARG A NH1 1 
ATOM   943   N NH2 . ARG A 1 124 ? -7.492  5.612   -2.907  1.00 54.62  ? 124 ARG A NH2 1 
ATOM   944   N N   . VAL A 1 125 ? -10.153 3.888   -9.879  1.00 55.31  ? 125 VAL A N   1 
ATOM   945   C CA  . VAL A 1 125 ? -11.597 3.754   -9.956  1.00 54.04  ? 125 VAL A CA  1 
ATOM   946   C C   . VAL A 1 125 ? -11.935 2.381   -10.562 1.00 55.77  ? 125 VAL A C   1 
ATOM   947   O O   . VAL A 1 125 ? -11.350 1.982   -11.554 1.00 57.41  ? 125 VAL A O   1 
ATOM   948   C CB  . VAL A 1 125 ? -12.248 4.927   -10.728 1.00 58.78  ? 125 VAL A CB  1 
ATOM   949   C CG1 . VAL A 1 125 ? -11.699 5.078   -12.138 1.00 59.93  ? 125 VAL A CG1 1 
ATOM   950   C CG2 . VAL A 1 125 ? -13.769 4.816   -10.747 1.00 61.70  ? 125 VAL A CG2 1 
ATOM   951   N N   . HIS A 1 126 ? -12.881 1.675   -9.912  1.00 58.87  ? 126 HIS A N   1 
ATOM   952   C CA  . HIS A 1 126 ? -13.207 0.277   -10.198 1.00 57.18  ? 126 HIS A CA  1 
ATOM   953   C C   . HIS A 1 126 ? -14.724 0.123   -10.354 1.00 52.35  ? 126 HIS A C   1 
ATOM   954   O O   . HIS A 1 126 ? -15.475 0.604   -9.520  1.00 44.33  ? 126 HIS A O   1 
ATOM   955   C CB  . HIS A 1 126 ? -12.869 -0.620  -8.989  1.00 60.06  ? 126 HIS A CB  1 
ATOM   956   C CG  . HIS A 1 126 ? -11.455 -0.762  -8.693  1.00 71.75  ? 126 HIS A CG  1 
ATOM   957   N ND1 . HIS A 1 126 ? -10.996 -0.866  -7.402  1.00 74.82  ? 126 HIS A ND1 1 
ATOM   958   C CD2 . HIS A 1 126 ? -10.377 -0.899  -9.498  1.00 93.71  ? 126 HIS A CD2 1 
ATOM   959   C CE1 . HIS A 1 126 ? -9.670  -1.040  -7.424  1.00 97.40  ? 126 HIS A CE1 1 
ATOM   960   N NE2 . HIS A 1 126 ? -9.276  -1.079  -8.690  1.00 100.66 ? 126 HIS A NE2 1 
ATOM   961   N N   . GLY A 1 127 ? -15.150 -0.688  -11.316 1.00 46.91  ? 127 GLY A N   1 
ATOM   962   C CA  . GLY A 1 127 ? -16.462 -1.304  -11.250 1.00 46.27  ? 127 GLY A CA  1 
ATOM   963   C C   . GLY A 1 127 ? -16.408 -2.604  -10.449 1.00 45.03  ? 127 GLY A C   1 
ATOM   964   O O   . GLY A 1 127 ? -15.353 -2.986  -9.987  1.00 47.81  ? 127 GLY A O   1 
ATOM   965   N N   . ARG A 1 128 ? -17.549 -3.316  -10.372 1.00 44.18  ? 128 ARG A N   1 
ATOM   966   C CA  . ARG A 1 128 ? -17.635 -4.576  -9.642  1.00 44.55  ? 128 ARG A CA  1 
ATOM   967   C C   . ARG A 1 128 ? -18.476 -5.587  -10.437 1.00 43.51  ? 128 ARG A C   1 
ATOM   968   O O   . ARG A 1 128 ? -19.320 -5.212  -11.246 1.00 41.33  ? 128 ARG A O   1 
ATOM   969   C CB  . ARG A 1 128 ? -18.255 -4.368  -8.253  1.00 52.46  ? 128 ARG A CB  1 
ATOM   970   C CG  . ARG A 1 128 ? -18.034 -2.974  -7.668  1.00 68.01  ? 128 ARG A CG  1 
ATOM   971   C CD  . ARG A 1 128 ? -18.378 -2.849  -6.166  1.00 76.90  ? 128 ARG A CD  1 
ATOM   972   N NE  . ARG A 1 128 ? -19.792 -3.122  -5.854  1.00 84.88  ? 128 ARG A NE  1 
ATOM   973   C CZ  . ARG A 1 128 ? -20.755 -2.182  -5.657  1.00 83.75  ? 128 ARG A CZ  1 
ATOM   974   N NH1 . ARG A 1 128 ? -20.504 -0.899  -5.895  1.00 70.60  ? 128 ARG A NH1 1 
ATOM   975   N NH2 . ARG A 1 128 ? -21.976 -2.550  -5.260  1.00 86.08  ? 128 ARG A NH2 1 
ATOM   976   N N   . ILE A 1 129 ? -18.264 -6.879  -10.146 1.00 42.66  ? 129 ILE A N   1 
ATOM   977   C CA  . ILE A 1 129 ? -19.125 -7.946  -10.630 1.00 43.05  ? 129 ILE A CA  1 
ATOM   978   C C   . ILE A 1 129 ? -19.738 -8.643  -9.420  1.00 45.67  ? 129 ILE A C   1 
ATOM   979   O O   . ILE A 1 129 ? -19.026 -9.028  -8.515  1.00 48.03  ? 129 ILE A O   1 
ATOM   980   C CB  . ILE A 1 129 ? -18.332 -8.927  -11.509 1.00 42.96  ? 129 ILE A CB  1 
ATOM   981   C CG1 . ILE A 1 129 ? -17.872 -8.276  -12.792 1.00 47.82  ? 129 ILE A CG1 1 
ATOM   982   C CG2 . ILE A 1 129 ? -19.139 -10.185 -11.783 1.00 43.01  ? 129 ILE A CG2 1 
ATOM   983   C CD1 . ILE A 1 129 ? -16.497 -8.713  -13.235 1.00 49.62  ? 129 ILE A CD1 1 
ATOM   984   N N   . VAL A 1 130 ? -21.062 -8.830  -9.441  1.00 46.93  ? 130 VAL A N   1 
ATOM   985   C CA  . VAL A 1 130 ? -21.795 -9.322  -8.285  1.00 48.08  ? 130 VAL A CA  1 
ATOM   986   C C   . VAL A 1 130 ? -22.476 -10.635 -8.655  1.00 53.41  ? 130 VAL A C   1 
ATOM   987   O O   . VAL A 1 130 ? -22.855 -10.840 -9.804  1.00 54.49  ? 130 VAL A O   1 
ATOM   988   C CB  . VAL A 1 130 ? -22.803 -8.268  -7.804  1.00 51.94  ? 130 VAL A CB  1 
ATOM   989   C CG1 . VAL A 1 130 ? -23.766 -8.826  -6.770  1.00 53.58  ? 130 VAL A CG1 1 
ATOM   990   C CG2 . VAL A 1 130 ? -22.094 -7.021  -7.259  1.00 49.65  ? 130 VAL A CG2 1 
ATOM   991   N N   . GLU A 1 131 ? -22.580 -11.544 -7.675  1.00 59.80  ? 131 GLU A N   1 
ATOM   992   C CA  . GLU A 1 131 ? -23.139 -12.870 -7.913  1.00 68.35  ? 131 GLU A CA  1 
ATOM   993   C C   . GLU A 1 131 ? -24.667 -12.763 -7.989  1.00 58.91  ? 131 GLU A C   1 
ATOM   994   O O   . GLU A 1 131 ? -25.252 -11.835 -7.456  1.00 56.85  ? 131 GLU A O   1 
ATOM   995   C CB  . GLU A 1 131 ? -22.695 -13.853 -6.813  1.00 86.67  ? 131 GLU A CB  1 
ATOM   996   C CG  . GLU A 1 131 ? -21.271 -14.394 -6.992  1.00 92.58  ? 131 GLU A CG  1 
ATOM   997   C CD  . GLU A 1 131 ? -20.915 -14.804 -8.430  1.00 105.67 ? 131 GLU A CD  1 
ATOM   998   O OE1 . GLU A 1 131 ? -19.877 -14.308 -8.929  1.00 104.93 ? 131 GLU A OE1 1 
ATOM   999   O OE2 . GLU A 1 131 ? -21.689 -15.580 -9.065  1.00 95.81  ? 131 GLU A OE2 1 
ATOM   1000  N N   . SER A 1 132 ? -25.302 -13.736 -8.644  1.00 52.45  ? 132 SER A N   1 
ATOM   1001  C CA  . SER A 1 132 ? -26.757 -13.756 -8.762  1.00 45.76  ? 132 SER A CA  1 
ATOM   1002  C C   . SER A 1 132 ? -27.315 -15.157 -8.435  1.00 47.73  ? 132 SER A C   1 
ATOM   1003  O O   . SER A 1 132 ? -26.725 -16.167 -8.798  1.00 47.62  ? 132 SER A O   1 
ATOM   1004  C CB  . SER A 1 132 ? -27.175 -13.307 -10.134 1.00 46.96  ? 132 SER A CB  1 
ATOM   1005  O OG  . SER A 1 132 ? -28.539 -13.622 -10.409 1.00 45.84  ? 132 SER A OG  1 
ATOM   1006  N N   . ASP A 1 133 ? -28.506 -15.193 -7.800  1.00 51.92  ? 133 ASP A N   1 
ATOM   1007  C CA  . ASP A 1 133 ? -29.215 -16.441 -7.555  1.00 52.28  ? 133 ASP A CA  1 
ATOM   1008  C C   . ASP A 1 133 ? -29.888 -16.943 -8.830  1.00 55.48  ? 133 ASP A C   1 
ATOM   1009  O O   . ASP A 1 133 ? -30.116 -18.146 -8.975  1.00 55.49  ? 133 ASP A O   1 
ATOM   1010  C CB  . ASP A 1 133 ? -30.190 -16.313 -6.404  1.00 49.99  ? 133 ASP A CB  1 
ATOM   1011  C CG  . ASP A 1 133 ? -29.541 -16.406 -5.026  1.00 54.97  ? 133 ASP A CG  1 
ATOM   1012  O OD1 . ASP A 1 133 ? -29.899 -15.616 -4.153  1.00 52.46  ? 133 ASP A OD1 1 
ATOM   1013  O OD2 . ASP A 1 133 ? -28.648 -17.248 -4.861  1.00 57.26  ? 133 ASP A OD2 1 
ATOM   1014  N N   . VAL A 1 134 ? -30.228 -16.023 -9.730  1.00 56.49  ? 134 VAL A N   1 
ATOM   1015  C CA  . VAL A 1 134 ? -30.905 -16.378 -10.969 1.00 52.62  ? 134 VAL A CA  1 
ATOM   1016  C C   . VAL A 1 134 ? -29.906 -17.072 -11.885 1.00 51.89  ? 134 VAL A C   1 
ATOM   1017  O O   . VAL A 1 134 ? -28.845 -16.524 -12.158 1.00 60.84  ? 134 VAL A O   1 
ATOM   1018  C CB  . VAL A 1 134 ? -31.493 -15.137 -11.659 1.00 59.81  ? 134 VAL A CB  1 
ATOM   1019  C CG1 . VAL A 1 134 ? -32.214 -15.503 -12.952 1.00 61.80  ? 134 VAL A CG1 1 
ATOM   1020  C CG2 . VAL A 1 134 ? -32.408 -14.343 -10.729 1.00 59.30  ? 134 VAL A CG2 1 
ATOM   1021  N N   . PRO A 1 135 ? -30.218 -18.281 -12.407 1.00 54.25  ? 135 PRO A N   1 
ATOM   1022  C CA  . PRO A 1 135 ? -29.322 -18.973 -13.333 1.00 53.86  ? 135 PRO A CA  1 
ATOM   1023  C C   . PRO A 1 135 ? -29.087 -18.165 -14.602 1.00 57.31  ? 135 PRO A C   1 
ATOM   1024  O O   . PRO A 1 135 ? -30.034 -17.701 -15.227 1.00 54.52  ? 135 PRO A O   1 
ATOM   1025  C CB  . PRO A 1 135 ? -30.046 -20.311 -13.633 1.00 57.39  ? 135 PRO A CB  1 
ATOM   1026  C CG  . PRO A 1 135 ? -31.075 -20.453 -12.491 1.00 57.80  ? 135 PRO A CG  1 
ATOM   1027  C CD  . PRO A 1 135 ? -31.452 -19.040 -12.134 1.00 59.82  ? 135 PRO A CD  1 
ATOM   1028  N N   . GLY A 1 136 ? -27.813 -18.005 -14.965 1.00 56.41  ? 136 GLY A N   1 
ATOM   1029  C CA  . GLY A 1 136 ? -27.436 -17.380 -16.221 1.00 53.81  ? 136 GLY A CA  1 
ATOM   1030  C C   . GLY A 1 136 ? -27.423 -15.851 -16.131 1.00 50.74  ? 136 GLY A C   1 
ATOM   1031  O O   . GLY A 1 136 ? -27.275 -15.186 -17.144 1.00 57.69  ? 136 GLY A O   1 
ATOM   1032  N N   . LYS A 1 137 ? -27.555 -15.307 -14.910 1.00 47.36  ? 137 LYS A N   1 
ATOM   1033  C CA  . LYS A 1 137 ? -27.597 -13.863 -14.714 1.00 48.99  ? 137 LYS A CA  1 
ATOM   1034  C C   . LYS A 1 137 ? -26.283 -13.371 -14.105 1.00 46.54  ? 137 LYS A C   1 
ATOM   1035  O O   . LYS A 1 137 ? -25.844 -13.873 -13.084 1.00 47.31  ? 137 LYS A O   1 
ATOM   1036  C CB  . LYS A 1 137 ? -28.768 -13.481 -13.811 1.00 56.22  ? 137 LYS A CB  1 
ATOM   1037  C CG  . LYS A 1 137 ? -29.052 -11.985 -13.756 1.00 64.49  ? 137 LYS A CG  1 
ATOM   1038  C CD  . LYS A 1 137 ? -30.539 -11.628 -13.670 1.00 66.56  ? 137 LYS A CD  1 
ATOM   1039  C CE  . LYS A 1 137 ? -30.898 -10.947 -12.390 1.00 74.04  ? 137 LYS A CE  1 
ATOM   1040  N NZ  . LYS A 1 137 ? -30.346 -9.589  -12.315 1.00 77.29  ? 137 LYS A NZ  1 
ATOM   1041  N N   . GLU A 1 138 ? -25.720 -12.337 -14.716 1.00 48.93  ? 138 GLU A N   1 
ATOM   1042  C CA  . GLU A 1 138 ? -24.512 -11.683 -14.232 1.00 51.12  ? 138 GLU A CA  1 
ATOM   1043  C C   . GLU A 1 138 ? -24.834 -10.210 -13.948 1.00 50.79  ? 138 GLU A C   1 
ATOM   1044  O O   . GLU A 1 138 ? -25.438 -9.536  -14.776 1.00 57.95  ? 138 GLU A O   1 
ATOM   1045  C CB  . GLU A 1 138 ? -23.417 -11.867 -15.294 1.00 54.20  ? 138 GLU A CB  1 
ATOM   1046  C CG  . GLU A 1 138 ? -22.266 -10.866 -15.220 1.00 55.99  ? 138 GLU A CG  1 
ATOM   1047  C CD  . GLU A 1 138 ? -21.257 -11.002 -16.370 1.00 63.66  ? 138 GLU A CD  1 
ATOM   1048  O OE1 . GLU A 1 138 ? -21.669 -11.291 -17.529 1.00 65.96  ? 138 GLU A OE1 1 
ATOM   1049  O OE2 . GLU A 1 138 ? -20.063 -10.766 -16.124 1.00 73.07  ? 138 GLU A OE2 1 
ATOM   1050  N N   . SER A 1 139 ? -24.445 -9.734  -12.758 1.00 44.25  ? 139 SER A N   1 
ATOM   1051  C CA  . SER A 1 139 ? -24.625 -8.341  -12.379 1.00 46.15  ? 139 SER A CA  1 
ATOM   1052  C C   . SER A 1 139 ? -23.293 -7.584  -12.498 1.00 46.05  ? 139 SER A C   1 
ATOM   1053  O O   . SER A 1 139 ? -22.327 -7.906  -11.830 1.00 43.09  ? 139 SER A O   1 
ATOM   1054  C CB  . SER A 1 139 ? -25.190 -8.222  -10.996 1.00 49.63  ? 139 SER A CB  1 
ATOM   1055  O OG  . SER A 1 139 ? -26.539 -8.650  -10.967 1.00 64.07  ? 139 SER A OG  1 
ATOM   1056  N N   . ARG A 1 140 ? -23.288 -6.547  -13.336 1.00 43.62  ? 140 ARG A N   1 
ATOM   1057  C CA  . ARG A 1 140 ? -22.137 -5.683  -13.517 1.00 42.22  ? 140 ARG A CA  1 
ATOM   1058  C C   . ARG A 1 140 ? -22.478 -4.297  -12.989 1.00 46.01  ? 140 ARG A C   1 
ATOM   1059  O O   . ARG A 1 140 ? -23.551 -3.784  -13.269 1.00 61.15  ? 140 ARG A O   1 
ATOM   1060  C CB  . ARG A 1 140 ? -21.723 -5.616  -14.989 1.00 50.00  ? 140 ARG A CB  1 
ATOM   1061  C CG  . ARG A 1 140 ? -21.159 -6.918  -15.534 1.00 50.00  ? 140 ARG A CG  1 
ATOM   1062  C CD  . ARG A 1 140 ? -20.703 -6.838  -16.982 1.00 50.00  ? 140 ARG A CD  1 
ATOM   1063  N NE  . ARG A 1 140 ? -21.362 -7.837  -17.819 1.00 50.00  ? 140 ARG A NE  1 
ATOM   1064  C CZ  . ARG A 1 140 ? -21.231 -7.909  -19.136 1.00 50.00  ? 140 ARG A CZ  1 
ATOM   1065  N NH1 . ARG A 1 140 ? -20.459 -7.040  -19.776 1.00 50.00  ? 140 ARG A NH1 1 
ATOM   1066  N NH2 . ARG A 1 140 ? -21.869 -8.851  -19.818 1.00 50.00  ? 140 ARG A NH2 1 
ATOM   1067  N N   . VAL A 1 141 ? -21.555 -3.701  -12.229 1.00 42.33  ? 141 VAL A N   1 
ATOM   1068  C CA  . VAL A 1 141 ? -21.715 -2.330  -11.768 1.00 41.24  ? 141 VAL A CA  1 
ATOM   1069  C C   . VAL A 1 141 ? -20.582 -1.498  -12.338 1.00 36.48  ? 141 VAL A C   1 
ATOM   1070  O O   . VAL A 1 141 ? -19.435 -1.756  -12.047 1.00 37.50  ? 141 VAL A O   1 
ATOM   1071  C CB  . VAL A 1 141 ? -21.754 -2.253  -10.231 1.00 45.90  ? 141 VAL A CB  1 
ATOM   1072  C CG1 . VAL A 1 141 ? -22.332 -0.928  -9.736  1.00 47.27  ? 141 VAL A CG1 1 
ATOM   1073  C CG2 . VAL A 1 141 ? -22.537 -3.414  -9.639  1.00 48.85  ? 141 VAL A CG2 1 
ATOM   1074  N N   . TYR A 1 142 ? -20.925 -0.491  -13.166 1.00 40.83  ? 142 TYR A N   1 
ATOM   1075  C CA  . TYR A 1 142 ? -19.924 0.395   -13.798 1.00 38.93  ? 142 TYR A CA  1 
ATOM   1076  C C   . TYR A 1 142 ? -19.821 1.729   -13.012 1.00 41.16  ? 142 TYR A C   1 
ATOM   1077  O O   . TYR A 1 142 ? -20.837 2.307   -12.607 1.00 43.25  ? 142 TYR A O   1 
ATOM   1078  C CB  . TYR A 1 142 ? -20.319 0.637   -15.255 1.00 36.12  ? 142 TYR A CB  1 
ATOM   1079  C CG  . TYR A 1 142 ? -20.200 -0.570  -16.186 1.00 42.39  ? 142 TYR A CG  1 
ATOM   1080  C CD1 . TYR A 1 142 ? -19.032 -0.829  -16.896 1.00 44.09  ? 142 TYR A CD1 1 
ATOM   1081  C CD2 . TYR A 1 142 ? -21.284 -1.434  -16.397 1.00 46.45  ? 142 TYR A CD2 1 
ATOM   1082  C CE1 . TYR A 1 142 ? -18.927 -1.939  -17.748 1.00 43.32  ? 142 TYR A CE1 1 
ATOM   1083  C CE2 . TYR A 1 142 ? -21.204 -2.521  -17.266 1.00 40.77  ? 142 TYR A CE2 1 
ATOM   1084  C CZ  . TYR A 1 142 ? -20.024 -2.783  -17.936 1.00 45.42  ? 142 TYR A CZ  1 
ATOM   1085  O OH  . TYR A 1 142 ? -19.966 -3.872  -18.768 1.00 42.66  ? 142 TYR A OH  1 
ATOM   1086  N N   . ARG A 1 143 ? -18.584 2.196   -12.790 1.00 44.22  ? 143 ARG A N   1 
ATOM   1087  C CA  . ARG A 1 143 ? -18.328 3.497   -12.159 1.00 47.01  ? 143 ARG A CA  1 
ATOM   1088  C C   . ARG A 1 143 ? -18.028 4.517   -13.250 1.00 48.50  ? 143 ARG A C   1 
ATOM   1089  O O   . ARG A 1 143 ? -17.157 4.294   -14.071 1.00 52.73  ? 143 ARG A O   1 
ATOM   1090  C CB  . ARG A 1 143 ? -17.100 3.475   -11.238 1.00 49.31  ? 143 ARG A CB  1 
ATOM   1091  C CG  . ARG A 1 143 ? -17.320 3.081   -9.790  1.00 54.14  ? 143 ARG A CG  1 
ATOM   1092  C CD  . ARG A 1 143 ? -17.533 4.259   -8.877  1.00 58.98  ? 143 ARG A CD  1 
ATOM   1093  N NE  . ARG A 1 143 ? -18.285 3.874   -7.671  1.00 74.93  ? 143 ARG A NE  1 
ATOM   1094  C CZ  . ARG A 1 143 ? -19.174 4.658   -7.007  1.00 90.00  ? 143 ARG A CZ  1 
ATOM   1095  N NH1 . ARG A 1 143 ? -19.410 5.915   -7.395  1.00 92.84  ? 143 ARG A NH1 1 
ATOM   1096  N NH2 . ARG A 1 143 ? -19.825 4.170   -5.967  1.00 95.03  ? 143 ARG A NH2 1 
ATOM   1097  N N   . SER A 1 144 ? -18.745 5.634   -13.244 1.00 52.08  ? 144 SER A N   1 
ATOM   1098  C CA  . SER A 1 144 ? -18.554 6.667   -14.259 1.00 52.87  ? 144 SER A CA  1 
ATOM   1099  C C   . SER A 1 144 ? -18.590 8.046   -13.620 1.00 54.08  ? 144 SER A C   1 
ATOM   1100  O O   . SER A 1 144 ? -19.088 8.220   -12.508 1.00 53.96  ? 144 SER A O   1 
ATOM   1101  C CB  . SER A 1 144 ? -19.577 6.557   -15.357 1.00 56.45  ? 144 SER A CB  1 
ATOM   1102  O OG  . SER A 1 144 ? -19.382 5.366   -16.119 1.00 65.42  ? 144 SER A OG  1 
ATOM   1103  N N   . ALA A 1 145 ? -18.074 9.022   -14.349 1.00 57.67  ? 145 ALA A N   1 
ATOM   1104  C CA  . ALA A 1 145 ? -18.074 10.395  -13.899 1.00 58.87  ? 145 ALA A CA  1 
ATOM   1105  C C   . ALA A 1 145 ? -19.508 10.895  -13.775 1.00 57.85  ? 145 ALA A C   1 
ATOM   1106  O O   . ALA A 1 145 ? -20.393 10.442  -14.488 1.00 54.07  ? 145 ALA A O   1 
ATOM   1107  C CB  . ALA A 1 145 ? -17.280 11.240  -14.855 1.00 60.95  ? 145 ALA A CB  1 
ATOM   1108  N N   . ILE A 1 146 ? -19.717 11.841  -12.859 1.00 62.47  ? 146 ILE A N   1 
ATOM   1109  C CA  . ILE A 1 146 ? -21.025 12.437  -12.648 1.00 56.14  ? 146 ILE A CA  1 
ATOM   1110  C C   . ILE A 1 146 ? -21.453 13.136  -13.930 1.00 49.89  ? 146 ILE A C   1 
ATOM   1111  O O   . ILE A 1 146 ? -22.550 12.923  -14.405 1.00 47.43  ? 146 ILE A O   1 
ATOM   1112  C CB  . ILE A 1 146 ? -20.999 13.407  -11.446 1.00 62.68  ? 146 ILE A CB  1 
ATOM   1113  C CG1 . ILE A 1 146 ? -20.748 12.679  -10.122 1.00 64.92  ? 146 ILE A CG1 1 
ATOM   1114  C CG2 . ILE A 1 146 ? -22.276 14.235  -11.387 1.00 61.76  ? 146 ILE A CG2 1 
ATOM   1115  C CD1 . ILE A 1 146 ? -21.778 11.613  -9.793  1.00 70.82  ? 146 ILE A CD1 1 
ATOM   1116  N N   . GLY A 1 147 ? -20.553 13.943  -14.495 1.00 48.01  ? 147 GLY A N   1 
ATOM   1117  C CA  . GLY A 1 147 ? -20.891 14.824  -15.607 1.00 50.65  ? 147 GLY A CA  1 
ATOM   1118  C C   . GLY A 1 147 ? -20.270 16.213  -15.418 1.00 51.04  ? 147 GLY A C   1 
ATOM   1119  O O   . GLY A 1 147 ? -19.082 16.398  -15.650 1.00 48.61  ? 147 GLY A O   1 
ATOM   1120  N N   . VAL A 1 148 ? -21.095 17.182  -14.973 1.00 55.63  ? 148 VAL A N   1 
ATOM   1121  C CA  . VAL A 1 148 ? -20.627 18.535  -14.706 1.00 56.79  ? 148 VAL A CA  1 
ATOM   1122  C C   . VAL A 1 148 ? -20.851 18.855  -13.238 1.00 52.13  ? 148 VAL A C   1 
ATOM   1123  O O   . VAL A 1 148 ? -21.907 18.572  -12.692 1.00 53.36  ? 148 VAL A O   1 
ATOM   1124  C CB  . VAL A 1 148 ? -21.307 19.580  -15.595 1.00 59.26  ? 148 VAL A CB  1 
ATOM   1125  C CG1 . VAL A 1 148 ? -20.808 20.983  -15.282 1.00 57.71  ? 148 VAL A CG1 1 
ATOM   1126  C CG2 . VAL A 1 148 ? -21.127 19.267  -17.073 1.00 62.27  ? 148 VAL A CG2 1 
ATOM   1127  N N   . VAL A 1 149 ? -19.841 19.457  -12.617 1.00 57.16  ? 149 VAL A N   1 
ATOM   1128  C CA  . VAL A 1 149 ? -19.897 19.808  -11.213 1.00 58.88  ? 149 VAL A CA  1 
ATOM   1129  C C   . VAL A 1 149 ? -19.727 21.314  -11.088 1.00 64.59  ? 149 VAL A C   1 
ATOM   1130  O O   . VAL A 1 149 ? -18.762 21.870  -11.601 1.00 58.56  ? 149 VAL A O   1 
ATOM   1131  C CB  . VAL A 1 149 ? -18.821 19.073  -10.397 1.00 57.60  ? 149 VAL A CB  1 
ATOM   1132  C CG1 . VAL A 1 149 ? -19.023 19.265  -8.901  1.00 57.50  ? 149 VAL A CG1 1 
ATOM   1133  C CG2 . VAL A 1 149 ? -18.763 17.587  -10.739 1.00 63.01  ? 149 VAL A CG2 1 
ATOM   1134  N N   . GLY A 1 150 ? -20.649 21.953  -10.349 1.00 67.80  ? 150 GLY A N   1 
ATOM   1135  C CA  . GLY A 1 150 ? -20.543 23.368  -10.038 1.00 63.42  ? 150 GLY A CA  1 
ATOM   1136  C C   . GLY A 1 150 ? -19.948 23.580  -8.647  1.00 65.03  ? 150 GLY A C   1 
ATOM   1137  O O   . GLY A 1 150 ? -20.376 22.938  -7.678  1.00 63.34  ? 150 GLY A O   1 
ATOM   1138  N N   . VAL A 1 151 ? -18.942 24.468  -8.566  1.00 61.91  ? 151 VAL A N   1 
ATOM   1139  C CA  . VAL A 1 151 ? -18.202 24.685  -7.330  1.00 62.02  ? 151 VAL A CA  1 
ATOM   1140  C C   . VAL A 1 151 ? -18.377 26.140  -6.906  1.00 63.52  ? 151 VAL A C   1 
ATOM   1141  O O   . VAL A 1 151 ? -18.055 27.060  -7.648  1.00 64.54  ? 151 VAL A O   1 
ATOM   1142  C CB  . VAL A 1 151 ? -16.707 24.323  -7.472  1.00 60.52  ? 151 VAL A CB  1 
ATOM   1143  C CG1 . VAL A 1 151 ? -15.950 24.532  -6.170  1.00 60.62  ? 151 VAL A CG1 1 
ATOM   1144  C CG2 . VAL A 1 151 ? -16.509 22.901  -7.980  1.00 64.05  ? 151 VAL A CG2 1 
ATOM   1145  N N   . ILE A 1 152 ? -18.866 26.327  -5.691  1.00 71.20  ? 152 ILE A N   1 
ATOM   1146  C CA  . ILE A 1 152 ? -18.962 27.639  -5.088  1.00 73.00  ? 152 ILE A CA  1 
ATOM   1147  C C   . ILE A 1 152 ? -17.781 27.820  -4.149  1.00 68.59  ? 152 ILE A C   1 
ATOM   1148  O O   . ILE A 1 152 ? -17.607 27.051  -3.215  1.00 59.79  ? 152 ILE A O   1 
ATOM   1149  C CB  . ILE A 1 152 ? -20.305 27.809  -4.358  1.00 75.70  ? 152 ILE A CB  1 
ATOM   1150  C CG1 . ILE A 1 152 ? -21.481 27.360  -5.241  1.00 72.59  ? 152 ILE A CG1 1 
ATOM   1151  C CG2 . ILE A 1 152 ? -20.477 29.243  -3.868  1.00 77.12  ? 152 ILE A CG2 1 
ATOM   1152  C CD1 . ILE A 1 152 ? -22.833 27.414  -4.556  1.00 72.74  ? 152 ILE A CD1 1 
ATOM   1153  N N   . SER A 1 153 ? -16.982 28.860  -4.415  1.00 76.18  ? 153 SER A N   1 
ATOM   1154  C CA  . SER A 1 153 ? -15.706 29.049  -3.758  1.00 74.39  ? 153 SER A CA  1 
ATOM   1155  C C   . SER A 1 153 ? -15.827 30.139  -2.694  1.00 82.28  ? 153 SER A C   1 
ATOM   1156  O O   . SER A 1 153 ? -16.466 31.167  -2.914  1.00 83.11  ? 153 SER A O   1 
ATOM   1157  C CB  . SER A 1 153 ? -14.637 29.377  -4.758  1.00 77.16  ? 153 SER A CB  1 
ATOM   1158  O OG  . SER A 1 153 ? -13.396 29.631  -4.116  1.00 93.21  ? 153 SER A OG  1 
ATOM   1159  N N   . PRO A 1 154 ? -15.214 29.944  -1.507  1.00 93.84  ? 154 PRO A N   1 
ATOM   1160  C CA  . PRO A 1 154 ? -15.163 30.988  -0.486  1.00 95.48  ? 154 PRO A CA  1 
ATOM   1161  C C   . PRO A 1 154 ? -13.943 31.894  -0.610  1.00 99.99  ? 154 PRO A C   1 
ATOM   1162  O O   . PRO A 1 154 ? -13.020 31.629  -1.396  1.00 99.66  ? 154 PRO A O   1 
ATOM   1163  C CB  . PRO A 1 154 ? -15.123 30.143  0.787   1.00 97.86  ? 154 PRO A CB  1 
ATOM   1164  C CG  . PRO A 1 154 ? -14.226 28.962  0.397   1.00 94.06  ? 154 PRO A CG  1 
ATOM   1165  C CD  . PRO A 1 154 ? -14.577 28.691  -1.071  1.00 94.52  ? 154 PRO A CD  1 
ATOM   1166  N N   . TRP A 1 155 ? -13.918 32.925  0.218   1.00 103.91 ? 155 TRP A N   1 
ATOM   1167  C CA  . TRP A 1 155 ? -12.896 33.945  0.130   1.00 107.97 ? 155 TRP A CA  1 
ATOM   1168  C C   . TRP A 1 155 ? -11.827 33.705  1.196   1.00 110.48 ? 155 TRP A C   1 
ATOM   1169  O O   . TRP A 1 155 ? -10.730 34.265  1.111   1.00 121.13 ? 155 TRP A O   1 
ATOM   1170  C CB  . TRP A 1 155 ? -13.532 35.333  0.265   1.00 114.70 ? 155 TRP A CB  1 
ATOM   1171  C CG  . TRP A 1 155 ? -14.272 35.536  1.553   1.00 109.57 ? 155 TRP A CG  1 
ATOM   1172  C CD1 . TRP A 1 155 ? -13.779 35.411  2.817   1.00 98.65  ? 155 TRP A CD1 1 
ATOM   1173  C CD2 . TRP A 1 155 ? -15.672 35.819  1.690   1.00 112.11 ? 155 TRP A CD2 1 
ATOM   1174  N NE1 . TRP A 1 155 ? -14.764 35.650  3.732   1.00 96.74  ? 155 TRP A NE1 1 
ATOM   1175  C CE2 . TRP A 1 155 ? -15.941 35.885  3.071   1.00 107.32 ? 155 TRP A CE2 1 
ATOM   1176  C CE3 . TRP A 1 155 ? -16.718 36.022  0.782   1.00 113.70 ? 155 TRP A CE3 1 
ATOM   1177  C CZ2 . TRP A 1 155 ? -17.216 36.151  3.562   1.00 112.81 ? 155 TRP A CZ2 1 
ATOM   1178  C CZ3 . TRP A 1 155 ? -17.980 36.277  1.270   1.00 112.31 ? 155 TRP A CZ3 1 
ATOM   1179  C CH2 . TRP A 1 155 ? -18.224 36.341  2.643   1.00 113.37 ? 155 TRP A CH2 1 
ATOM   1180  N N   . ASN A 1 156 ? -12.152 32.837  2.180   1.00 108.78 ? 156 ASN A N   1 
ATOM   1181  C CA  . ASN A 1 156 ? -11.249 32.529  3.288   1.00 110.82 ? 156 ASN A CA  1 
ATOM   1182  C C   . ASN A 1 156 ? -9.951  31.907  2.746   1.00 107.26 ? 156 ASN A C   1 
ATOM   1183  O O   . ASN A 1 156 ? -8.882  32.516  2.841   1.00 126.64 ? 156 ASN A O   1 
ATOM   1184  C CB  . ASN A 1 156 ? -11.929 31.642  4.337   1.00 111.83 ? 156 ASN A CB  1 
ATOM   1185  C CG  . ASN A 1 156 ? -11.014 31.307  5.507   1.00 121.54 ? 156 ASN A CG  1 
ATOM   1186  O OD1 . ASN A 1 156 ? -10.180 32.128  5.909   1.00 117.82 ? 156 ASN A OD1 1 
ATOM   1187  N ND2 . ASN A 1 156 ? -11.149 30.109  6.063   1.00 135.50 ? 156 ASN A ND2 1 
ATOM   1188  N N   . PHE A 1 157 ? -10.051 30.683  2.208   1.00 91.32  ? 157 PHE A N   1 
ATOM   1189  C CA  . PHE A 1 157 ? -8.930  30.039  1.535   1.00 87.74  ? 157 PHE A CA  1 
ATOM   1190  C C   . PHE A 1 157 ? -9.330  29.735  0.105   1.00 79.26  ? 157 PHE A C   1 
ATOM   1191  O O   . PHE A 1 157 ? -9.520  28.579  -0.248  1.00 71.23  ? 157 PHE A O   1 
ATOM   1192  C CB  . PHE A 1 157 ? -8.522  28.744  2.234   1.00 103.54 ? 157 PHE A CB  1 
ATOM   1193  C CG  . PHE A 1 157 ? -7.638  28.927  3.451   1.00 115.92 ? 157 PHE A CG  1 
ATOM   1194  C CD1 . PHE A 1 157 ? -8.175  29.370  4.655   1.00 125.81 ? 157 PHE A CD1 1 
ATOM   1195  C CD2 . PHE A 1 157 ? -6.278  28.611  3.405   1.00 118.58 ? 157 PHE A CD2 1 
ATOM   1196  C CE1 . PHE A 1 157 ? -7.373  29.521  5.778   1.00 139.56 ? 157 PHE A CE1 1 
ATOM   1197  C CE2 . PHE A 1 157 ? -5.475  28.763  4.528   1.00 130.19 ? 157 PHE A CE2 1 
ATOM   1198  C CZ  . PHE A 1 157 ? -6.025  29.211  5.717   1.00 145.42 ? 157 PHE A CZ  1 
ATOM   1199  N N   . PRO A 1 158 ? -9.473  30.758  -0.763  1.00 77.95  ? 158 PRO A N   1 
ATOM   1200  C CA  . PRO A 1 158 ? -10.078 30.560  -2.074  1.00 80.91  ? 158 PRO A CA  1 
ATOM   1201  C C   . PRO A 1 158 ? -9.344  29.512  -2.916  1.00 77.91  ? 158 PRO A C   1 
ATOM   1202  O O   . PRO A 1 158 ? -9.973  28.607  -3.439  1.00 73.65  ? 158 PRO A O   1 
ATOM   1203  C CB  . PRO A 1 158 ? -10.037 31.968  -2.704  1.00 77.12  ? 158 PRO A CB  1 
ATOM   1204  C CG  . PRO A 1 158 ? -8.926  32.677  -1.947  1.00 76.24  ? 158 PRO A CG  1 
ATOM   1205  C CD  . PRO A 1 158 ? -8.986  32.124  -0.556  1.00 74.52  ? 158 PRO A CD  1 
ATOM   1206  N N   . LEU A 1 159 ? -8.002  29.635  -3.006  1.00 82.83  ? 159 LEU A N   1 
ATOM   1207  C CA  . LEU A 1 159 ? -7.184  28.811  -3.911  1.00 85.58  ? 159 LEU A CA  1 
ATOM   1208  C C   . LEU A 1 159 ? -7.296  27.324  -3.519  1.00 78.12  ? 159 LEU A C   1 
ATOM   1209  O O   . LEU A 1 159 ? -7.722  26.497  -4.320  1.00 75.17  ? 159 LEU A O   1 
ATOM   1210  C CB  . LEU A 1 159 ? -5.731  29.322  -3.859  1.00 82.19  ? 159 LEU A CB  1 
ATOM   1211  C CG  . LEU A 1 159 ? -4.789  28.954  -5.026  1.00 77.65  ? 159 LEU A CG  1 
ATOM   1212  C CD1 . LEU A 1 159 ? -4.453  27.480  -5.061  1.00 77.25  ? 159 LEU A CD1 1 
ATOM   1213  C CD2 . LEU A 1 159 ? -5.344  29.407  -6.360  1.00 79.46  ? 159 LEU A CD2 1 
ATOM   1214  N N   . HIS A 1 160 ? -6.942  27.009  -2.273  1.00 73.99  ? 160 HIS A N   1 
ATOM   1215  C CA  . HIS A 1 160 ? -6.805  25.627  -1.830  1.00 77.67  ? 160 HIS A CA  1 
ATOM   1216  C C   . HIS A 1 160 ? -8.171  24.926  -1.786  1.00 72.60  ? 160 HIS A C   1 
ATOM   1217  O O   . HIS A 1 160 ? -8.284  23.755  -2.170  1.00 62.05  ? 160 HIS A O   1 
ATOM   1218  C CB  . HIS A 1 160 ? -6.093  25.564  -0.473  1.00 90.02  ? 160 HIS A CB  1 
ATOM   1219  C CG  . HIS A 1 160 ? -6.441  24.356  0.331   1.00 93.28  ? 160 HIS A CG  1 
ATOM   1220  N ND1 . HIS A 1 160 ? -7.201  24.428  1.479   1.00 102.22 ? 160 HIS A ND1 1 
ATOM   1221  C CD2 . HIS A 1 160 ? -6.133  23.062  0.170   1.00 90.81  ? 160 HIS A CD2 1 
ATOM   1222  C CE1 . HIS A 1 160 ? -7.352  23.214  1.980   1.00 99.28  ? 160 HIS A CE1 1 
ATOM   1223  N NE2 . HIS A 1 160 ? -6.717  22.368  1.200   1.00 93.40  ? 160 HIS A NE2 1 
ATOM   1224  N N   . LEU A 1 161 ? -9.196  25.636  -1.300  1.00 64.07  ? 161 LEU A N   1 
ATOM   1225  C CA  . LEU A 1 161 ? -10.528 25.052  -1.165  1.00 66.22  ? 161 LEU A CA  1 
ATOM   1226  C C   . LEU A 1 161 ? -11.171 24.845  -2.538  1.00 63.67  ? 161 LEU A C   1 
ATOM   1227  O O   . LEU A 1 161 ? -11.953 23.925  -2.696  1.00 70.01  ? 161 LEU A O   1 
ATOM   1228  C CB  . LEU A 1 161 ? -11.417 25.896  -0.261  1.00 67.70  ? 161 LEU A CB  1 
ATOM   1229  C CG  . LEU A 1 161 ? -11.064 25.862  1.226   1.00 76.40  ? 161 LEU A CG  1 
ATOM   1230  C CD1 . LEU A 1 161 ? -12.159 26.510  2.059   1.00 80.66  ? 161 LEU A CD1 1 
ATOM   1231  C CD2 . LEU A 1 161 ? -10.800 24.433  1.693   1.00 75.29  ? 161 LEU A CD2 1 
ATOM   1232  N N   . THR A 1 162 ? -10.836 25.703  -3.529  1.00 61.60  ? 162 THR A N   1 
ATOM   1233  C CA  . THR A 1 162 ? -11.318 25.503  -4.900  1.00 59.85  ? 162 THR A CA  1 
ATOM   1234  C C   . THR A 1 162 ? -10.712 24.212  -5.453  1.00 56.22  ? 162 THR A C   1 
ATOM   1235  O O   . THR A 1 162 ? -11.436 23.332  -5.913  1.00 56.23  ? 162 THR A O   1 
ATOM   1236  C CB  . THR A 1 162 ? -10.988 26.700  -5.805  1.00 55.38  ? 162 THR A CB  1 
ATOM   1237  O OG1 . THR A 1 162 ? -11.441 27.876  -5.150  1.00 57.09  ? 162 THR A OG1 1 
ATOM   1238  C CG2 . THR A 1 162 ? -11.688 26.622  -7.148  1.00 55.76  ? 162 THR A CG2 1 
ATOM   1239  N N   . GLN A 1 163 ? -9.380  24.104  -5.385  1.00 54.13  ? 163 GLN A N   1 
ATOM   1240  C CA  . GLN A 1 163 ? -8.665  22.994  -6.014  1.00 62.62  ? 163 GLN A CA  1 
ATOM   1241  C C   . GLN A 1 163 ? -9.086  21.657  -5.367  1.00 60.22  ? 163 GLN A C   1 
ATOM   1242  O O   . GLN A 1 163 ? -9.067  20.619  -6.014  1.00 51.74  ? 163 GLN A O   1 
ATOM   1243  C CB  . GLN A 1 163 ? -7.150  23.213  -5.915  1.00 61.38  ? 163 GLN A CB  1 
ATOM   1244  C CG  . GLN A 1 163 ? -6.318  22.182  -6.680  1.00 56.86  ? 163 GLN A CG  1 
ATOM   1245  C CD  . GLN A 1 163 ? -6.183  22.497  -8.158  1.00 53.47  ? 163 GLN A CD  1 
ATOM   1246  O OE1 . GLN A 1 163 ? -7.064  23.112  -8.770  1.00 51.37  ? 163 GLN A OE1 1 
ATOM   1247  N NE2 . GLN A 1 163 ? -5.064  22.081  -8.747  1.00 54.06  ? 163 GLN A NE2 1 
ATOM   1248  N N   . ARG A 1 164 ? -9.461  21.715  -4.092  1.00 55.25  ? 164 ARG A N   1 
ATOM   1249  C CA  . ARG A 1 164 ? -9.903  20.549  -3.355  1.00 60.15  ? 164 ARG A CA  1 
ATOM   1250  C C   . ARG A 1 164 ? -11.071 19.871  -4.087  1.00 58.81  ? 164 ARG A C   1 
ATOM   1251  O O   . ARG A 1 164 ? -11.223 18.657  -4.009  1.00 62.82  ? 164 ARG A O   1 
ATOM   1252  C CB  . ARG A 1 164 ? -10.306 20.979  -1.942  1.00 64.87  ? 164 ARG A CB  1 
ATOM   1253  C CG  . ARG A 1 164 ? -10.449 19.847  -0.938  1.00 73.94  ? 164 ARG A CG  1 
ATOM   1254  C CD  . ARG A 1 164 ? -11.736 19.980  -0.164  1.00 84.81  ? 164 ARG A CD  1 
ATOM   1255  N NE  . ARG A 1 164 ? -11.619 19.606  1.244   1.00 96.50  ? 164 ARG A NE  1 
ATOM   1256  C CZ  . ARG A 1 164 ? -12.487 19.997  2.188   1.00 119.84 ? 164 ARG A CZ  1 
ATOM   1257  N NH1 . ARG A 1 164 ? -12.224 19.767  3.457   1.00 125.22 ? 164 ARG A NH1 1 
ATOM   1258  N NH2 . ARG A 1 164 ? -13.575 20.687  1.853   1.00 130.48 ? 164 ARG A NH2 1 
ATOM   1259  N N   . SER A 1 165 ? -11.904 20.670  -4.778  1.00 58.93  ? 165 SER A N   1 
ATOM   1260  C CA  . SER A 1 165 ? -13.014 20.130  -5.573  1.00 59.08  ? 165 SER A CA  1 
ATOM   1261  C C   . SER A 1 165 ? -12.593 19.934  -7.029  1.00 56.95  ? 165 SER A C   1 
ATOM   1262  O O   . SER A 1 165 ? -12.927 18.922  -7.643  1.00 63.26  ? 165 SER A O   1 
ATOM   1263  C CB  . SER A 1 165 ? -14.241 21.006  -5.487  1.00 54.49  ? 165 SER A CB  1 
ATOM   1264  O OG  . SER A 1 165 ? -14.609 21.229  -4.138  1.00 51.88  ? 165 SER A OG  1 
ATOM   1265  N N   . ILE A 1 166 ? -11.851 20.898  -7.567  1.00 53.93  ? 166 ILE A N   1 
ATOM   1266  C CA  . ILE A 1 166 ? -11.584 20.962  -9.001  1.00 54.22  ? 166 ILE A CA  1 
ATOM   1267  C C   . ILE A 1 166 ? -10.751 19.744  -9.424  1.00 49.58  ? 166 ILE A C   1 
ATOM   1268  O O   . ILE A 1 166 ? -11.100 19.058  -10.374 1.00 44.84  ? 166 ILE A O   1 
ATOM   1269  C CB  . ILE A 1 166 ? -10.878 22.290  -9.358  1.00 65.25  ? 166 ILE A CB  1 
ATOM   1270  C CG1 . ILE A 1 166 ? -11.706 23.472  -8.972  1.00 72.09  ? 166 ILE A CG1 1 
ATOM   1271  C CG2 . ILE A 1 166 ? -10.499 22.341  -10.830 1.00 73.12  ? 166 ILE A CG2 1 
ATOM   1272  C CD1 . ILE A 1 166 ? -13.178 23.302  -9.254  1.00 70.87  ? 166 ILE A CD1 1 
ATOM   1273  N N   . ALA A 1 167 ? -9.632  19.500  -8.710  1.00 51.39  ? 167 ALA A N   1 
ATOM   1274  C CA  . ALA A 1 167 ? -8.610  18.546  -9.157  1.00 53.50  ? 167 ALA A CA  1 
ATOM   1275  C C   . ALA A 1 167 ? -9.174  17.112  -9.215  1.00 51.87  ? 167 ALA A C   1 
ATOM   1276  O O   . ALA A 1 167 ? -9.082  16.453  -10.253 1.00 44.82  ? 167 ALA A O   1 
ATOM   1277  C CB  . ALA A 1 167 ? -7.373  18.633  -8.273  1.00 52.80  ? 167 ALA A CB  1 
ATOM   1278  N N   . PRO A 1 168 ? -9.766  16.566  -8.132  1.00 49.97  ? 168 PRO A N   1 
ATOM   1279  C CA  . PRO A 1 168 ? -10.281 15.209  -8.197  1.00 53.11  ? 168 PRO A CA  1 
ATOM   1280  C C   . PRO A 1 168 ? -11.423 15.115  -9.209  1.00 49.26  ? 168 PRO A C   1 
ATOM   1281  O O   . PRO A 1 168 ? -11.442 14.206  -10.033 1.00 44.68  ? 168 PRO A O   1 
ATOM   1282  C CB  . PRO A 1 168 ? -10.712 14.882  -6.753  1.00 55.76  ? 168 PRO A CB  1 
ATOM   1283  C CG  . PRO A 1 168 ? -10.897 16.257  -6.098  1.00 54.51  ? 168 PRO A CG  1 
ATOM   1284  C CD  . PRO A 1 168 ? -9.895  17.167  -6.792  1.00 51.55  ? 168 PRO A CD  1 
ATOM   1285  N N   . ALA A 1 169 ? -12.335 16.098  -9.197  1.00 49.04  ? 169 ALA A N   1 
ATOM   1286  C CA  . ALA A 1 169 ? -13.471 16.063  -10.122 1.00 47.26  ? 169 ALA A CA  1 
ATOM   1287  C C   . ALA A 1 169 ? -12.968 15.942  -11.554 1.00 47.47  ? 169 ALA A C   1 
ATOM   1288  O O   . ALA A 1 169 ? -13.426 15.083  -12.297 1.00 48.49  ? 169 ALA A O   1 
ATOM   1289  C CB  . ALA A 1 169 ? -14.346 17.265  -9.946  1.00 45.55  ? 169 ALA A CB  1 
ATOM   1290  N N   . LEU A 1 170 ? -12.001 16.790  -11.922 1.00 50.23  ? 170 LEU A N   1 
ATOM   1291  C CA  . LEU A 1 170 ? -11.489 16.818  -13.289 1.00 56.88  ? 170 LEU A CA  1 
ATOM   1292  C C   . LEU A 1 170 ? -10.782 15.500  -13.597 1.00 52.77  ? 170 LEU A C   1 
ATOM   1293  O O   . LEU A 1 170 ? -10.921 14.955  -14.689 1.00 47.64  ? 170 LEU A O   1 
ATOM   1294  C CB  . LEU A 1 170 ? -10.548 18.009  -13.487 1.00 64.16  ? 170 LEU A CB  1 
ATOM   1295  C CG  . LEU A 1 170 ? -11.201 19.348  -13.852 1.00 67.64  ? 170 LEU A CG  1 
ATOM   1296  C CD1 . LEU A 1 170 ? -10.180 20.482  -13.753 1.00 69.52  ? 170 LEU A CD1 1 
ATOM   1297  C CD2 . LEU A 1 170 ? -11.810 19.294  -15.249 1.00 70.91  ? 170 LEU A CD2 1 
ATOM   1298  N N   . ALA A 1 171 ? -9.983  15.024  -12.639 1.00 45.24  ? 171 ALA A N   1 
ATOM   1299  C CA  . ALA A 1 171 ? -9.208  13.817  -12.833 1.00 42.06  ? 171 ALA A CA  1 
ATOM   1300  C C   . ALA A 1 171 ? -10.140 12.641  -13.103 1.00 40.65  ? 171 ALA A C   1 
ATOM   1301  O O   . ALA A 1 171 ? -9.843  11.790  -13.944 1.00 34.83  ? 171 ALA A O   1 
ATOM   1302  C CB  . ALA A 1 171 ? -8.340  13.568  -11.630 1.00 45.40  ? 171 ALA A CB  1 
ATOM   1303  N N   . LEU A 1 172 ? -11.287 12.614  -12.394 1.00 40.12  ? 172 LEU A N   1 
ATOM   1304  C CA  . LEU A 1 172 ? -12.205 11.489  -12.471 1.00 42.48  ? 172 LEU A CA  1 
ATOM   1305  C C   . LEU A 1 172 ? -13.115 11.618  -13.709 1.00 48.36  ? 172 LEU A C   1 
ATOM   1306  O O   . LEU A 1 172 ? -14.075 10.859  -13.845 1.00 46.12  ? 172 LEU A O   1 
ATOM   1307  C CB  . LEU A 1 172 ? -13.031 11.388  -11.184 1.00 43.10  ? 172 LEU A CB  1 
ATOM   1308  C CG  . LEU A 1 172 ? -12.429 10.594  -10.006 1.00 47.50  ? 172 LEU A CG  1 
ATOM   1309  C CD1 . LEU A 1 172 ? -11.383 9.607   -10.450 1.00 46.81  ? 172 LEU A CD1 1 
ATOM   1310  C CD2 . LEU A 1 172 ? -11.888 11.484  -8.930  1.00 50.37  ? 172 LEU A CD2 1 
ATOM   1311  N N   . GLY A 1 173 ? -12.823 12.593  -14.595 1.00 53.98  ? 173 GLY A N   1 
ATOM   1312  C CA  . GLY A 1 173 ? -13.471 12.668  -15.907 1.00 55.87  ? 173 GLY A CA  1 
ATOM   1313  C C   . GLY A 1 173 ? -14.699 13.587  -15.914 1.00 51.96  ? 173 GLY A C   1 
ATOM   1314  O O   . GLY A 1 173 ? -15.437 13.629  -16.893 1.00 54.96  ? 173 GLY A O   1 
ATOM   1315  N N   . ASN A 1 174 ? -14.912 14.326  -14.830 1.00 53.73  ? 174 ASN A N   1 
ATOM   1316  C CA  . ASN A 1 174 ? -15.985 15.321  -14.801 1.00 57.83  ? 174 ASN A CA  1 
ATOM   1317  C C   . ASN A 1 174 ? -15.536 16.618  -15.477 1.00 53.09  ? 174 ASN A C   1 
ATOM   1318  O O   . ASN A 1 174 ? -14.344 16.837  -15.705 1.00 44.43  ? 174 ASN A O   1 
ATOM   1319  C CB  . ASN A 1 174 ? -16.450 15.628  -13.386 1.00 62.85  ? 174 ASN A CB  1 
ATOM   1320  C CG  . ASN A 1 174 ? -17.186 14.469  -12.763 1.00 57.34  ? 174 ASN A CG  1 
ATOM   1321  O OD1 . ASN A 1 174 ? -18.281 14.095  -13.224 1.00 55.54  ? 174 ASN A OD1 1 
ATOM   1322  N ND2 . ASN A 1 174 ? -16.601 13.887  -11.731 1.00 51.50  ? 174 ASN A ND2 1 
ATOM   1323  N N   . ALA A 1 175 ? -16.528 17.473  -15.793 1.00 55.61  ? 175 ALA A N   1 
ATOM   1324  C CA  . ALA A 1 175 ? -16.289 18.872  -16.124 1.00 53.77  ? 175 ALA A CA  1 
ATOM   1325  C C   . ALA A 1 175 ? -16.772 19.758  -14.973 1.00 53.15  ? 175 ALA A C   1 
ATOM   1326  O O   . ALA A 1 175 ? -17.593 19.341  -14.141 1.00 47.83  ? 175 ALA A O   1 
ATOM   1327  C CB  . ALA A 1 175 ? -16.980 19.225  -17.428 1.00 52.30  ? 175 ALA A CB  1 
ATOM   1328  N N   . VAL A 1 176 ? -16.263 20.989  -14.944 1.00 53.96  ? 176 VAL A N   1 
ATOM   1329  C CA  . VAL A 1 176 ? -16.429 21.841  -13.788 1.00 62.45  ? 176 VAL A CA  1 
ATOM   1330  C C   . VAL A 1 176 ? -16.642 23.316  -14.217 1.00 65.19  ? 176 VAL A C   1 
ATOM   1331  O O   . VAL A 1 176 ? -16.030 23.799  -15.192 1.00 63.78  ? 176 VAL A O   1 
ATOM   1332  C CB  . VAL A 1 176 ? -15.220 21.666  -12.850 1.00 66.47  ? 176 VAL A CB  1 
ATOM   1333  C CG1 . VAL A 1 176 ? -13.947 21.328  -13.601 1.00 73.58  ? 176 VAL A CG1 1 
ATOM   1334  C CG2 . VAL A 1 176 ? -15.008 22.869  -11.983 1.00 72.62  ? 176 VAL A CG2 1 
ATOM   1335  N N   . VAL A 1 177 ? -17.551 24.002  -13.464 1.00 62.71  ? 177 VAL A N   1 
ATOM   1336  C CA  . VAL A 1 177 ? -17.783 25.447  -13.548 1.00 65.47  ? 177 VAL A CA  1 
ATOM   1337  C C   . VAL A 1 177 ? -17.687 26.050  -12.135 1.00 62.16  ? 177 VAL A C   1 
ATOM   1338  O O   . VAL A 1 177 ? -18.340 25.574  -11.207 1.00 56.20  ? 177 VAL A O   1 
ATOM   1339  C CB  . VAL A 1 177 ? -19.160 25.752  -14.162 1.00 70.72  ? 177 VAL A CB  1 
ATOM   1340  C CG1 . VAL A 1 177 ? -19.590 27.176  -13.881 1.00 78.30  ? 177 VAL A CG1 1 
ATOM   1341  C CG2 . VAL A 1 177 ? -19.200 25.469  -15.654 1.00 77.27  ? 177 VAL A CG2 1 
ATOM   1342  N N   . VAL A 1 178 ? -16.901 27.118  -11.991 1.00 57.10  ? 178 VAL A N   1 
ATOM   1343  C CA  . VAL A 1 178 ? -16.623 27.681  -10.680 1.00 66.24  ? 178 VAL A CA  1 
ATOM   1344  C C   . VAL A 1 178 ? -17.215 29.087  -10.606 1.00 72.03  ? 178 VAL A C   1 
ATOM   1345  O O   . VAL A 1 178 ? -17.048 29.879  -11.518 1.00 72.70  ? 178 VAL A O   1 
ATOM   1346  C CB  . VAL A 1 178 ? -15.111 27.698  -10.379 1.00 70.58  ? 178 VAL A CB  1 
ATOM   1347  C CG1 . VAL A 1 178 ? -14.792 28.381  -9.041  1.00 67.35  ? 178 VAL A CG1 1 
ATOM   1348  C CG2 . VAL A 1 178 ? -14.520 26.297  -10.420 1.00 70.87  ? 178 VAL A CG2 1 
ATOM   1349  N N   . LYS A 1 179 ? -17.912 29.369  -9.506  1.00 75.10  ? 179 LYS A N   1 
ATOM   1350  C CA  . LYS A 1 179 ? -18.402 30.704  -9.214  1.00 79.57  ? 179 LYS A CA  1 
ATOM   1351  C C   . LYS A 1 179 ? -17.711 31.187  -7.956  1.00 74.09  ? 179 LYS A C   1 
ATOM   1352  O O   . LYS A 1 179 ? -18.066 30.780  -6.852  1.00 74.86  ? 179 LYS A O   1 
ATOM   1353  C CB  . LYS A 1 179 ? -19.929 30.677  -9.070  1.00 86.02  ? 179 LYS A CB  1 
ATOM   1354  C CG  . LYS A 1 179 ? -20.574 31.829  -8.313  1.00 83.53  ? 179 LYS A CG  1 
ATOM   1355  C CD  . LYS A 1 179 ? -21.990 31.470  -7.871  1.00 88.48  ? 179 LYS A CD  1 
ATOM   1356  C CE  . LYS A 1 179 ? -22.709 32.552  -7.160  1.00 87.99  ? 179 LYS A CE  1 
ATOM   1357  N NZ  . LYS A 1 179 ? -21.942 33.026  -6.016  1.00 90.98  ? 179 LYS A NZ  1 
ATOM   1358  N N   . PRO A 1 180 ? -16.665 32.014  -8.087  1.00 70.23  ? 180 PRO A N   1 
ATOM   1359  C CA  . PRO A 1 180 ? -15.838 32.381  -6.944  1.00 70.92  ? 180 PRO A CA  1 
ATOM   1360  C C   . PRO A 1 180 ? -16.472 33.480  -6.108  1.00 72.59  ? 180 PRO A C   1 
ATOM   1361  O O   . PRO A 1 180 ? -17.473 34.069  -6.503  1.00 69.69  ? 180 PRO A O   1 
ATOM   1362  C CB  . PRO A 1 180 ? -14.553 32.828  -7.617  1.00 77.68  ? 180 PRO A CB  1 
ATOM   1363  C CG  . PRO A 1 180 ? -15.034 33.465  -8.916  1.00 80.04  ? 180 PRO A CG  1 
ATOM   1364  C CD  . PRO A 1 180 ? -16.226 32.631  -9.346  1.00 73.86  ? 180 PRO A CD  1 
ATOM   1365  N N   . ALA A 1 181 ? -15.876 33.749  -4.948  1.00 80.75  ? 181 ALA A N   1 
ATOM   1366  C CA  . ALA A 1 181 ? -16.289 34.879  -4.134  1.00 91.14  ? 181 ALA A CA  1 
ATOM   1367  C C   . ALA A 1 181 ? -15.905 36.182  -4.846  1.00 97.12  ? 181 ALA A C   1 
ATOM   1368  O O   . ALA A 1 181 ? -14.875 36.250  -5.521  1.00 96.52  ? 181 ALA A O   1 
ATOM   1369  C CB  . ALA A 1 181 ? -15.667 34.782  -2.755  1.00 91.13  ? 181 ALA A CB  1 
ATOM   1370  N N   . SER A 1 182 ? -16.749 37.211  -4.696  1.00 106.47 ? 182 SER A N   1 
ATOM   1371  C CA  . SER A 1 182 ? -16.554 38.477  -5.401  1.00 103.94 ? 182 SER A CA  1 
ATOM   1372  C C   . SER A 1 182 ? -15.278 39.188  -4.907  1.00 95.56  ? 182 SER A C   1 
ATOM   1373  O O   . SER A 1 182 ? -14.613 39.863  -5.684  1.00 87.90  ? 182 SER A O   1 
ATOM   1374  C CB  . SER A 1 182 ? -17.775 39.367  -5.278  1.00 98.93  ? 182 SER A CB  1 
ATOM   1375  O OG  . SER A 1 182 ? -18.239 39.420  -3.939  1.00 97.34  ? 182 SER A OG  1 
ATOM   1376  N N   . ASP A 1 183 ? -14.915 38.974  -3.631  1.00 92.90  ? 183 ASP A N   1 
ATOM   1377  C CA  . ASP A 1 183 ? -13.727 39.593  -3.049  1.00 98.41  ? 183 ASP A CA  1 
ATOM   1378  C C   . ASP A 1 183 ? -12.446 38.920  -3.575  1.00 98.89  ? 183 ASP A C   1 
ATOM   1379  O O   . ASP A 1 183 ? -11.390 39.549  -3.609  1.00 95.51  ? 183 ASP A O   1 
ATOM   1380  C CB  . ASP A 1 183 ? -13.782 39.580  -1.529  1.00 106.03 ? 183 ASP A CB  1 
ATOM   1381  C CG  . ASP A 1 183 ? -14.881 40.433  -0.907  1.00 111.92 ? 183 ASP A CG  1 
ATOM   1382  O OD1 . ASP A 1 183 ? -15.671 41.029  -1.671  1.00 120.94 ? 183 ASP A OD1 1 
ATOM   1383  O OD2 . ASP A 1 183 ? -14.941 40.490  0.330   1.00 105.67 ? 183 ASP A OD2 1 
ATOM   1384  N N   . THR A 1 184 ? -12.536 37.629  -3.944  1.00 101.73 ? 184 THR A N   1 
ATOM   1385  C CA  . THR A 1 184 ? -11.359 36.868  -4.371  1.00 96.66  ? 184 THR A CA  1 
ATOM   1386  C C   . THR A 1 184 ? -11.672 36.115  -5.668  1.00 89.37  ? 184 THR A C   1 
ATOM   1387  O O   . THR A 1 184 ? -11.661 34.887  -5.691  1.00 77.47  ? 184 THR A O   1 
ATOM   1388  C CB  . THR A 1 184 ? -10.905 35.904  -3.255  1.00 100.13 ? 184 THR A CB  1 
ATOM   1389  O OG1 . THR A 1 184 ? -12.030 35.121  -2.857  1.00 85.17  ? 184 THR A OG1 1 
ATOM   1390  C CG2 . THR A 1 184 ? -10.340 36.626  -2.040  1.00 102.12 ? 184 THR A CG2 1 
ATOM   1391  N N   . PRO A 1 185 ? -11.916 36.823  -6.798  1.00 80.32  ? 185 PRO A N   1 
ATOM   1392  C CA  . PRO A 1 185 ? -12.183 36.154  -8.066  1.00 76.92  ? 185 PRO A CA  1 
ATOM   1393  C C   . PRO A 1 185 ? -10.957 35.450  -8.657  1.00 77.42  ? 185 PRO A C   1 
ATOM   1394  O O   . PRO A 1 185 ? -11.087 34.385  -9.232  1.00 85.15  ? 185 PRO A O   1 
ATOM   1395  C CB  . PRO A 1 185 ? -12.686 37.294  -8.952  1.00 76.33  ? 185 PRO A CB  1 
ATOM   1396  C CG  . PRO A 1 185 ? -11.980 38.508  -8.409  1.00 77.60  ? 185 PRO A CG  1 
ATOM   1397  C CD  . PRO A 1 185 ? -11.948 38.284  -6.907  1.00 77.64  ? 185 PRO A CD  1 
ATOM   1398  N N   . VAL A 1 186 ? -9.769  36.045  -8.485  1.00 78.73  ? 186 VAL A N   1 
ATOM   1399  C CA  . VAL A 1 186 ? -8.555  35.514  -9.094  1.00 81.73  ? 186 VAL A CA  1 
ATOM   1400  C C   . VAL A 1 186 ? -8.182  34.185  -8.414  1.00 81.97  ? 186 VAL A C   1 
ATOM   1401  O O   . VAL A 1 186 ? -8.094  33.151  -9.074  1.00 81.04  ? 186 VAL A O   1 
ATOM   1402  C CB  . VAL A 1 186 ? -7.390  36.532  -9.059  1.00 79.16  ? 186 VAL A CB  1 
ATOM   1403  C CG1 . VAL A 1 186 ? -6.026  35.853  -9.038  1.00 77.83  ? 186 VAL A CG1 1 
ATOM   1404  C CG2 . VAL A 1 186 ? -7.476  37.524  -10.223 1.00 84.94  ? 186 VAL A CG2 1 
ATOM   1405  N N   . CYS A 1 187 ? -7.930  34.231  -7.101  1.00 80.67  ? 187 CYS A N   1 
ATOM   1406  C CA  . CYS A 1 187 ? -7.629  32.989  -6.341  1.00 84.45  ? 187 CYS A CA  1 
ATOM   1407  C C   . CYS A 1 187 ? -8.938  32.204  -6.237  1.00 79.43  ? 187 CYS A C   1 
ATOM   1408  O O   . CYS A 1 187 ? -8.970  31.200  -5.507  1.00 76.33  ? 187 CYS A O   1 
ATOM   1409  C CB  . CYS A 1 187 ? -7.048  33.326  -4.974  1.00 91.96  ? 187 CYS A CB  1 
ATOM   1410  S SG  . CYS A 1 187 ? -5.891  34.720  -5.010  1.00 95.46  ? 187 CYS A SG  1 
ATOM   1411  N N   . GLY A 1 188 ? -9.934  32.600  -7.024  1.00 76.69  ? 188 GLY A N   1 
ATOM   1412  C CA  . GLY A 1 188 ? -11.262 31.962  -7.026  1.00 74.76  ? 188 GLY A CA  1 
ATOM   1413  C C   . GLY A 1 188 ? -11.293 30.940  -8.131  1.00 70.38  ? 188 GLY A C   1 
ATOM   1414  O O   . GLY A 1 188 ? -12.389 30.446  -8.446  1.00 77.77  ? 188 GLY A O   1 
ATOM   1415  N N   . GLY A 1 189 ? -10.129 30.636  -8.705  1.00 64.39  ? 189 GLY A N   1 
ATOM   1416  C CA  . GLY A 1 189 ? -10.053 29.731  -9.864  1.00 69.47  ? 189 GLY A CA  1 
ATOM   1417  C C   . GLY A 1 189 ? -9.958  30.475  -11.171 1.00 68.13  ? 189 GLY A C   1 
ATOM   1418  O O   . GLY A 1 189 ? -9.770  29.806  -12.203 1.00 69.17  ? 189 GLY A O   1 
ATOM   1419  N N   . LEU A 1 190 ? -10.032 31.806  -11.147 1.00 76.83  ? 190 LEU A N   1 
ATOM   1420  C CA  . LEU A 1 190 ? -9.743  32.551  -12.397 1.00 75.64  ? 190 LEU A CA  1 
ATOM   1421  C C   . LEU A 1 190 ? -8.278  32.228  -12.710 1.00 67.49  ? 190 LEU A C   1 
ATOM   1422  O O   . LEU A 1 190 ? -7.948  32.003  -13.892 1.00 68.03  ? 190 LEU A O   1 
ATOM   1423  C CB  . LEU A 1 190 ? -9.951  34.052  -12.225 1.00 80.01  ? 190 LEU A CB  1 
ATOM   1424  C CG  . LEU A 1 190 ? -11.272 34.619  -12.748 1.00 81.59  ? 190 LEU A CG  1 
ATOM   1425  C CD1 . LEU A 1 190 ? -11.363 36.095  -12.413 1.00 83.43  ? 190 LEU A CD1 1 
ATOM   1426  C CD2 . LEU A 1 190 ? -11.377 34.407  -14.245 1.00 78.74  ? 190 LEU A CD2 1 
ATOM   1427  N N   . LEU A 1 191 ? -7.441  32.194  -11.670 1.00 63.97  ? 191 LEU A N   1 
ATOM   1428  C CA  . LEU A 1 191 ? -6.010  31.847  -11.839 1.00 66.61  ? 191 LEU A CA  1 
ATOM   1429  C C   . LEU A 1 191 ? -5.867  30.326  -12.015 1.00 70.12  ? 191 LEU A C   1 
ATOM   1430  O O   . LEU A 1 191 ? -5.089  29.904  -12.897 1.00 65.87  ? 191 LEU A O   1 
ATOM   1431  C CB  . LEU A 1 191 ? -5.254  32.337  -10.607 1.00 71.64  ? 191 LEU A CB  1 
ATOM   1432  C CG  . LEU A 1 191 ? -3.749  32.057  -10.578 1.00 80.53  ? 191 LEU A CG  1 
ATOM   1433  C CD1 . LEU A 1 191 ? -3.033  32.943  -11.581 1.00 82.05  ? 191 LEU A CD1 1 
ATOM   1434  C CD2 . LEU A 1 191 ? -3.200  32.280  -9.179  1.00 79.24  ? 191 LEU A CD2 1 
ATOM   1435  N N   . LEU A 1 192 ? -6.588  29.537  -11.209 1.00 68.43  ? 192 LEU A N   1 
ATOM   1436  C CA  . LEU A 1 192 ? -6.491  28.079  -11.365 1.00 61.92  ? 192 LEU A CA  1 
ATOM   1437  C C   . LEU A 1 192 ? -6.754  27.669  -12.825 1.00 66.05  ? 192 LEU A C   1 
ATOM   1438  O O   . LEU A 1 192 ? -6.183  26.697  -13.305 1.00 56.95  ? 192 LEU A O   1 
ATOM   1439  C CB  . LEU A 1 192 ? -7.440  27.370  -10.408 1.00 55.61  ? 192 LEU A CB  1 
ATOM   1440  C CG  . LEU A 1 192 ? -6.947  27.251  -8.974  1.00 54.60  ? 192 LEU A CG  1 
ATOM   1441  C CD1 . LEU A 1 192 ? -7.999  26.719  -8.067  1.00 58.86  ? 192 LEU A CD1 1 
ATOM   1442  C CD2 . LEU A 1 192 ? -5.737  26.381  -8.925  1.00 59.23  ? 192 LEU A CD2 1 
ATOM   1443  N N   . ALA A 1 193 ? -7.591  28.437  -13.534 1.00 66.63  ? 193 ALA A N   1 
ATOM   1444  C CA  . ALA A 1 193 ? -7.957  28.103  -14.908 1.00 61.29  ? 193 ALA A CA  1 
ATOM   1445  C C   . ALA A 1 193 ? -6.738  28.207  -15.849 1.00 63.22  ? 193 ALA A C   1 
ATOM   1446  O O   . ALA A 1 193 ? -6.580  27.378  -16.751 1.00 70.14  ? 193 ALA A O   1 
ATOM   1447  C CB  . ALA A 1 193 ? -9.091  28.988  -15.361 1.00 61.96  ? 193 ALA A CB  1 
ATOM   1448  N N   . ARG A 1 194 ? -5.883  29.228  -15.633 1.00 60.09  ? 194 ARG A N   1 
ATOM   1449  C CA  . ARG A 1 194 ? -4.696  29.428  -16.460 1.00 68.27  ? 194 ARG A CA  1 
ATOM   1450  C C   . ARG A 1 194 ? -3.728  28.278  -16.243 1.00 61.43  ? 194 ARG A C   1 
ATOM   1451  O O   . ARG A 1 194 ? -3.131  27.787  -17.203 1.00 65.82  ? 194 ARG A O   1 
ATOM   1452  C CB  . ARG A 1 194 ? -3.981  30.763  -16.171 1.00 84.25  ? 194 ARG A CB  1 
ATOM   1453  C CG  . ARG A 1 194 ? -4.799  32.009  -16.496 1.00 91.51  ? 194 ARG A CG  1 
ATOM   1454  C CD  . ARG A 1 194 ? -5.126  32.132  -17.988 1.00 102.45 ? 194 ARG A CD  1 
ATOM   1455  N NE  . ARG A 1 194 ? -4.044  32.789  -18.724 1.00 111.24 ? 194 ARG A NE  1 
ATOM   1456  C CZ  . ARG A 1 194 ? -3.709  34.074  -18.592 1.00 100.48 ? 194 ARG A CZ  1 
ATOM   1457  N NH1 . ARG A 1 194 ? -2.575  34.508  -19.115 1.00 102.21 ? 194 ARG A NH1 1 
ATOM   1458  N NH2 . ARG A 1 194 ? -4.489  34.910  -17.905 1.00 81.27  ? 194 ARG A NH2 1 
ATOM   1459  N N   . ILE A 1 195 ? -3.575  27.856  -14.966 1.00 59.36  ? 195 ILE A N   1 
ATOM   1460  C CA  . ILE A 1 195 ? -2.667  26.771  -14.622 1.00 54.43  ? 195 ILE A CA  1 
ATOM   1461  C C   . ILE A 1 195 ? -3.106  25.510  -15.351 1.00 57.06  ? 195 ILE A C   1 
ATOM   1462  O O   . ILE A 1 195 ? -2.281  24.852  -15.985 1.00 52.51  ? 195 ILE A O   1 
ATOM   1463  C CB  . ILE A 1 195 ? -2.576  26.554  -13.102 1.00 58.57  ? 195 ILE A CB  1 
ATOM   1464  C CG1 . ILE A 1 195 ? -1.872  27.740  -12.394 1.00 53.52  ? 195 ILE A CG1 1 
ATOM   1465  C CG2 . ILE A 1 195 ? -1.878  25.219  -12.778 1.00 56.97  ? 195 ILE A CG2 1 
ATOM   1466  C CD1 . ILE A 1 195 ? -2.133  27.805  -10.898 1.00 52.11  ? 195 ILE A CD1 1 
ATOM   1467  N N   . PHE A 1 196 ? -4.419  25.199  -15.290 1.00 62.18  ? 196 PHE A N   1 
ATOM   1468  C CA  . PHE A 1 196 ? -4.941  23.983  -15.902 1.00 65.59  ? 196 PHE A CA  1 
ATOM   1469  C C   . PHE A 1 196 ? -4.826  24.095  -17.417 1.00 65.08  ? 196 PHE A C   1 
ATOM   1470  O O   . PHE A 1 196 ? -4.561  23.102  -18.087 1.00 63.74  ? 196 PHE A O   1 
ATOM   1471  C CB  . PHE A 1 196 ? -6.382  23.664  -15.474 1.00 65.27  ? 196 PHE A CB  1 
ATOM   1472  C CG  . PHE A 1 196 ? -6.463  22.677  -14.315 1.00 62.95  ? 196 PHE A CG  1 
ATOM   1473  C CD1 . PHE A 1 196 ? -6.159  21.331  -14.499 1.00 61.51  ? 196 PHE A CD1 1 
ATOM   1474  C CD2 . PHE A 1 196 ? -6.797  23.101  -13.031 1.00 58.25  ? 196 PHE A CD2 1 
ATOM   1475  C CE1 . PHE A 1 196 ? -6.194  20.449  -13.430 1.00 52.45  ? 196 PHE A CE1 1 
ATOM   1476  C CE2 . PHE A 1 196 ? -6.828  22.209  -11.975 1.00 52.28  ? 196 PHE A CE2 1 
ATOM   1477  C CZ  . PHE A 1 196 ? -6.542  20.891  -12.180 1.00 52.57  ? 196 PHE A CZ  1 
ATOM   1478  N N   . GLU A 1 197 ? -5.010  25.308  -17.950 1.00 68.09  ? 197 GLU A N   1 
ATOM   1479  C CA  . GLU A 1 197 ? -4.871  25.519  -19.382 1.00 72.61  ? 197 GLU A CA  1 
ATOM   1480  C C   . GLU A 1 197 ? -3.410  25.280  -19.794 1.00 74.20  ? 197 GLU A C   1 
ATOM   1481  O O   . GLU A 1 197 ? -3.143  24.585  -20.782 1.00 76.82  ? 197 GLU A O   1 
ATOM   1482  C CB  . GLU A 1 197 ? -5.342  26.905  -19.801 1.00 73.10  ? 197 GLU A CB  1 
ATOM   1483  C CG  . GLU A 1 197 ? -5.931  26.923  -21.209 1.00 78.00  ? 197 GLU A CG  1 
ATOM   1484  C CD  . GLU A 1 197 ? -5.797  28.242  -21.940 1.00 85.22  ? 197 GLU A CD  1 
ATOM   1485  O OE1 . GLU A 1 197 ? -6.667  28.544  -22.794 1.00 85.50  ? 197 GLU A OE1 1 
ATOM   1486  O OE2 . GLU A 1 197 ? -4.803  28.951  -21.682 1.00 95.50  ? 197 GLU A OE2 1 
ATOM   1487  N N   . GLU A 1 198 ? -2.472  25.838  -19.017 1.00 66.14  ? 198 GLU A N   1 
ATOM   1488  C CA  . GLU A 1 198 ? -1.052  25.641  -19.275 1.00 70.76  ? 198 GLU A CA  1 
ATOM   1489  C C   . GLU A 1 198 ? -0.693  24.148  -19.144 1.00 72.23  ? 198 GLU A C   1 
ATOM   1490  O O   . GLU A 1 198 ? 0.237   23.677  -19.793 1.00 69.34  ? 198 GLU A O   1 
ATOM   1491  C CB  . GLU A 1 198 ? -0.207  26.514  -18.346 1.00 69.43  ? 198 GLU A CB  1 
ATOM   1492  C CG  . GLU A 1 198 ? 1.296   26.287  -18.502 1.00 75.10  ? 198 GLU A CG  1 
ATOM   1493  C CD  . GLU A 1 198 ? 2.147   27.484  -18.166 1.00 80.25  ? 198 GLU A CD  1 
ATOM   1494  O OE1 . GLU A 1 198 ? 1.884   28.124  -17.134 1.00 69.73  ? 198 GLU A OE1 1 
ATOM   1495  O OE2 . GLU A 1 198 ? 3.093   27.764  -18.935 1.00 93.06  ? 198 GLU A OE2 1 
ATOM   1496  N N   . ALA A 1 199 ? -1.438  23.410  -18.302 1.00 66.68  ? 199 ALA A N   1 
ATOM   1497  C CA  . ALA A 1 199 ? -1.156  21.992  -18.072 1.00 68.08  ? 199 ALA A CA  1 
ATOM   1498  C C   . ALA A 1 199 ? -1.817  21.116  -19.149 1.00 65.88  ? 199 ALA A C   1 
ATOM   1499  O O   . ALA A 1 199 ? -1.714  19.895  -19.095 1.00 65.61  ? 199 ALA A O   1 
ATOM   1500  C CB  . ALA A 1 199 ? -1.612  21.583  -16.673 1.00 71.23  ? 199 ALA A CB  1 
ATOM   1501  N N   . GLY A 1 200 ? -2.533  21.741  -20.094 1.00 63.71  ? 200 GLY A N   1 
ATOM   1502  C CA  . GLY A 1 200 ? -3.004  21.041  -21.286 1.00 60.60  ? 200 GLY A CA  1 
ATOM   1503  C C   . GLY A 1 200 ? -4.455  20.564  -21.152 1.00 61.60  ? 200 GLY A C   1 
ATOM   1504  O O   . GLY A 1 200 ? -4.920  19.750  -21.969 1.00 55.47  ? 200 GLY A O   1 
ATOM   1505  N N   . LEU A 1 201 ? -5.184  21.102  -20.155 1.00 59.88  ? 201 LEU A N   1 
ATOM   1506  C CA  . LEU A 1 201 ? -6.607  20.798  -20.003 1.00 69.01  ? 201 LEU A CA  1 
ATOM   1507  C C   . LEU A 1 201 ? -7.353  21.270  -21.259 1.00 69.90  ? 201 LEU A C   1 
ATOM   1508  O O   . LEU A 1 201 ? -7.225  22.430  -21.661 1.00 73.74  ? 201 LEU A O   1 
ATOM   1509  C CB  . LEU A 1 201 ? -7.187  21.439  -18.734 1.00 67.25  ? 201 LEU A CB  1 
ATOM   1510  C CG  . LEU A 1 201 ? -8.609  21.000  -18.339 1.00 69.33  ? 201 LEU A CG  1 
ATOM   1511  C CD1 . LEU A 1 201 ? -8.643  19.570  -17.785 1.00 68.07  ? 201 LEU A CD1 1 
ATOM   1512  C CD2 . LEU A 1 201 ? -9.211  21.963  -17.327 1.00 72.47  ? 201 LEU A CD2 1 
ATOM   1513  N N   . PRO A 1 202 ? -8.142  20.384  -21.920 1.00 70.69  ? 202 PRO A N   1 
ATOM   1514  C CA  . PRO A 1 202 ? -8.957  20.789  -23.069 1.00 68.34  ? 202 PRO A CA  1 
ATOM   1515  C C   . PRO A 1 202 ? -9.916  21.937  -22.756 1.00 68.44  ? 202 PRO A C   1 
ATOM   1516  O O   . PRO A 1 202 ? -10.377 22.083  -21.628 1.00 58.83  ? 202 PRO A O   1 
ATOM   1517  C CB  . PRO A 1 202 ? -9.712  19.493  -23.440 1.00 68.76  ? 202 PRO A CB  1 
ATOM   1518  C CG  . PRO A 1 202 ? -8.833  18.386  -22.889 1.00 68.68  ? 202 PRO A CG  1 
ATOM   1519  C CD  . PRO A 1 202 ? -8.260  18.948  -21.614 1.00 66.81  ? 202 PRO A CD  1 
ATOM   1520  N N   . ALA A 1 203 ? -10.228 22.729  -23.788 1.00 80.72  ? 203 ALA A N   1 
ATOM   1521  C CA  . ALA A 1 203 ? -11.018 23.949  -23.631 1.00 76.30  ? 203 ALA A CA  1 
ATOM   1522  C C   . ALA A 1 203 ? -12.482 23.600  -23.415 1.00 70.71  ? 203 ALA A C   1 
ATOM   1523  O O   . ALA A 1 203 ? -13.023 22.728  -24.088 1.00 64.00  ? 203 ALA A O   1 
ATOM   1524  C CB  . ALA A 1 203 ? -10.845 24.840  -24.844 1.00 77.85  ? 203 ALA A CB  1 
ATOM   1525  N N   . GLY A 1 204 ? -13.115 24.302  -22.474 1.00 74.15  ? 204 GLY A N   1 
ATOM   1526  C CA  . GLY A 1 204 ? -14.538 24.139  -22.231 1.00 77.54  ? 204 GLY A CA  1 
ATOM   1527  C C   . GLY A 1 204 ? -14.825 23.352  -20.952 1.00 69.91  ? 204 GLY A C   1 
ATOM   1528  O O   . GLY A 1 204 ? -15.930 23.413  -20.435 1.00 63.75  ? 204 GLY A O   1 
ATOM   1529  N N   . LEU A 1 205 ? -13.825 22.611  -20.447 1.00 73.33  ? 205 LEU A N   1 
ATOM   1530  C CA  . LEU A 1 205 ? -14.028 21.744  -19.282 1.00 65.55  ? 205 LEU A CA  1 
ATOM   1531  C C   . LEU A 1 205 ? -14.027 22.579  -17.992 1.00 62.03  ? 205 LEU A C   1 
ATOM   1532  O O   . LEU A 1 205 ? -14.654 22.188  -17.020 1.00 68.29  ? 205 LEU A O   1 
ATOM   1533  C CB  . LEU A 1 205 ? -12.966 20.640  -19.227 1.00 64.81  ? 205 LEU A CB  1 
ATOM   1534  C CG  . LEU A 1 205 ? -13.065 19.544  -20.300 1.00 61.13  ? 205 LEU A CG  1 
ATOM   1535  C CD1 . LEU A 1 205 ? -11.788 18.712  -20.320 1.00 62.34  ? 205 LEU A CD1 1 
ATOM   1536  C CD2 . LEU A 1 205 ? -14.285 18.637  -20.102 1.00 59.95  ? 205 LEU A CD2 1 
ATOM   1537  N N   . PHE A 1 206 ? -13.300 23.717  -17.991 1.00 59.54  ? 206 PHE A N   1 
ATOM   1538  C CA  . PHE A 1 206 ? -13.137 24.541  -16.787 1.00 61.86  ? 206 PHE A CA  1 
ATOM   1539  C C   . PHE A 1 206 ? -13.557 25.979  -17.093 1.00 71.05  ? 206 PHE A C   1 
ATOM   1540  O O   . PHE A 1 206 ? -12.817 26.731  -17.746 1.00 69.51  ? 206 PHE A O   1 
ATOM   1541  C CB  . PHE A 1 206 ? -11.686 24.532  -16.283 1.00 60.75  ? 206 PHE A CB  1 
ATOM   1542  C CG  . PHE A 1 206 ? -11.445 25.221  -14.936 1.00 53.99  ? 206 PHE A CG  1 
ATOM   1543  C CD1 . PHE A 1 206 ? -12.463 25.900  -14.271 1.00 52.00  ? 206 PHE A CD1 1 
ATOM   1544  C CD2 . PHE A 1 206 ? -10.192 25.186  -14.343 1.00 51.08  ? 206 PHE A CD2 1 
ATOM   1545  C CE1 . PHE A 1 206 ? -12.226 26.513  -13.051 1.00 54.15  ? 206 PHE A CE1 1 
ATOM   1546  C CE2 . PHE A 1 206 ? -9.966  25.804  -13.122 1.00 55.88  ? 206 PHE A CE2 1 
ATOM   1547  C CZ  . PHE A 1 206 ? -10.982 26.463  -12.481 1.00 55.34  ? 206 PHE A CZ  1 
ATOM   1548  N N   . SER A 1 207 ? -14.721 26.370  -16.559 1.00 75.35  ? 207 SER A N   1 
ATOM   1549  C CA  . SER A 1 207 ? -15.257 27.706  -16.758 1.00 74.43  ? 207 SER A CA  1 
ATOM   1550  C C   . SER A 1 207 ? -15.358 28.443  -15.420 1.00 75.88  ? 207 SER A C   1 
ATOM   1551  O O   . SER A 1 207 ? -15.649 27.839  -14.386 1.00 70.02  ? 207 SER A O   1 
ATOM   1552  C CB  . SER A 1 207 ? -16.592 27.655  -17.461 1.00 65.09  ? 207 SER A CB  1 
ATOM   1553  O OG  . SER A 1 207 ? -16.423 27.774  -18.865 1.00 57.37  ? 207 SER A OG  1 
ATOM   1554  N N   . VAL A 1 208 ? -15.123 29.762  -15.465 1.00 75.88  ? 208 VAL A N   1 
ATOM   1555  C CA  . VAL A 1 208 ? -15.301 30.620  -14.305 1.00 77.18  ? 208 VAL A CA  1 
ATOM   1556  C C   . VAL A 1 208 ? -16.272 31.747  -14.681 1.00 87.38  ? 208 VAL A C   1 
ATOM   1557  O O   . VAL A 1 208 ? -16.012 32.508  -15.626 1.00 98.09  ? 208 VAL A O   1 
ATOM   1558  C CB  . VAL A 1 208 ? -13.949 31.179  -13.789 1.00 76.93  ? 208 VAL A CB  1 
ATOM   1559  C CG1 . VAL A 1 208 ? -14.130 32.087  -12.575 1.00 76.58  ? 208 VAL A CG1 1 
ATOM   1560  C CG2 . VAL A 1 208 ? -12.950 30.069  -13.470 1.00 78.11  ? 208 VAL A CG2 1 
ATOM   1561  N N   . VAL A 1 209 ? -17.377 31.865  -13.903 1.00 86.51  ? 209 VAL A N   1 
ATOM   1562  C CA  . VAL A 1 209 ? -18.323 32.972  -14.045 1.00 79.46  ? 209 VAL A CA  1 
ATOM   1563  C C   . VAL A 1 209 ? -18.257 33.866  -12.799 1.00 87.56  ? 209 VAL A C   1 
ATOM   1564  O O   . VAL A 1 209 ? -18.615 33.450  -11.686 1.00 87.22  ? 209 VAL A O   1 
ATOM   1565  C CB  . VAL A 1 209 ? -19.764 32.519  -14.330 1.00 67.97  ? 209 VAL A CB  1 
ATOM   1566  C CG1 . VAL A 1 209 ? -20.092 32.621  -15.797 1.00 77.91  ? 209 VAL A CG1 1 
ATOM   1567  C CG2 . VAL A 1 209 ? -20.034 31.124  -13.845 1.00 76.46  ? 209 VAL A CG2 1 
ATOM   1568  N N   . VAL A 1 210 ? -17.769 35.095  -13.031 1.00 87.83  ? 210 VAL A N   1 
ATOM   1569  C CA  . VAL A 1 210 ? -17.809 36.186  -12.085 1.00 86.85  ? 210 VAL A CA  1 
ATOM   1570  C C   . VAL A 1 210 ? -18.878 37.163  -12.557 1.00 93.56  ? 210 VAL A C   1 
ATOM   1571  O O   . VAL A 1 210 ? -18.775 37.714  -13.649 1.00 95.81  ? 210 VAL A O   1 
ATOM   1572  C CB  . VAL A 1 210 ? -16.418 36.854  -12.023 1.00 85.97  ? 210 VAL A CB  1 
ATOM   1573  C CG1 . VAL A 1 210 ? -16.337 37.934  -10.960 1.00 87.57  ? 210 VAL A CG1 1 
ATOM   1574  C CG2 . VAL A 1 210 ? -15.311 35.834  -11.822 1.00 90.14  ? 210 VAL A CG2 1 
ATOM   1575  N N   . GLY A 1 211 ? -19.928 37.321  -11.760 1.00 100.49 ? 211 GLY A N   1 
ATOM   1576  C CA  . GLY A 1 211 ? -21.055 38.142  -12.152 1.00 113.96 ? 211 GLY A CA  1 
ATOM   1577  C C   . GLY A 1 211 ? -21.695 38.818  -10.950 1.00 123.78 ? 211 GLY A C   1 
ATOM   1578  O O   . GLY A 1 211 ? -21.291 38.585  -9.808  1.00 122.38 ? 211 GLY A O   1 
ATOM   1579  N N   . PRO A 1 212 ? -22.716 39.679  -11.173 1.00 135.85 ? 212 PRO A N   1 
ATOM   1580  C CA  . PRO A 1 212 ? -23.440 40.303  -10.076 1.00 133.84 ? 212 PRO A CA  1 
ATOM   1581  C C   . PRO A 1 212 ? -24.246 39.252  -9.317  1.00 136.64 ? 212 PRO A C   1 
ATOM   1582  O O   . PRO A 1 212 ? -25.058 38.534  -9.913  1.00 147.47 ? 212 PRO A O   1 
ATOM   1583  C CB  . PRO A 1 212 ? -24.327 41.352  -10.788 1.00 133.20 ? 212 PRO A CB  1 
ATOM   1584  C CG  . PRO A 1 212 ? -24.562 40.756  -12.170 1.00 134.48 ? 212 PRO A CG  1 
ATOM   1585  C CD  . PRO A 1 212 ? -23.272 40.018  -12.496 1.00 138.98 ? 212 PRO A CD  1 
ATOM   1586  N N   . GLY A 1 213 ? -24.001 39.168  -8.000  1.00 128.92 ? 213 GLY A N   1 
ATOM   1587  C CA  . GLY A 1 213 ? -24.611 38.152  -7.151  1.00 136.59 ? 213 GLY A CA  1 
ATOM   1588  C C   . GLY A 1 213 ? -26.144 38.211  -7.189  1.00 147.44 ? 213 GLY A C   1 
ATOM   1589  O O   . GLY A 1 213 ? -26.808 37.212  -6.910  1.00 141.28 ? 213 GLY A O   1 
ATOM   1590  N N   . SER A 1 214 ? -26.692 39.397  -7.518  1.00 160.73 ? 214 SER A N   1 
ATOM   1591  C CA  . SER A 1 214 ? -28.137 39.597  -7.595  1.00 153.36 ? 214 SER A CA  1 
ATOM   1592  C C   . SER A 1 214 ? -28.735 38.720  -8.699  1.00 143.17 ? 214 SER A C   1 
ATOM   1593  O O   . SER A 1 214 ? -29.691 37.989  -8.460  1.00 145.61 ? 214 SER A O   1 
ATOM   1594  C CB  . SER A 1 214 ? -28.482 41.066  -7.805  1.00 148.46 ? 214 SER A CB  1 
ATOM   1595  O OG  . SER A 1 214 ? -27.792 41.603  -8.925  1.00 147.91 ? 214 SER A OG  1 
ATOM   1596  N N   . GLU A 1 215 ? -28.147 38.790  -9.901  1.00 129.58 ? 215 GLU A N   1 
ATOM   1597  C CA  . GLU A 1 215 ? -28.701 38.124  -11.070 1.00 122.89 ? 215 GLU A CA  1 
ATOM   1598  C C   . GLU A 1 215 ? -28.428 36.616  -10.999 1.00 134.28 ? 215 GLU A C   1 
ATOM   1599  O O   . GLU A 1 215 ? -29.360 35.818  -10.917 1.00 140.87 ? 215 GLU A O   1 
ATOM   1600  C CB  . GLU A 1 215 ? -28.117 38.730  -12.342 1.00 114.01 ? 215 GLU A CB  1 
ATOM   1601  C CG  . GLU A 1 215 ? -28.740 38.172  -13.614 1.00 112.05 ? 215 GLU A CG  1 
ATOM   1602  C CD  . GLU A 1 215 ? -28.086 38.668  -14.887 1.00 116.26 ? 215 GLU A CD  1 
ATOM   1603  O OE1 . GLU A 1 215 ? -27.040 39.348  -14.794 1.00 121.53 ? 215 GLU A OE1 1 
ATOM   1604  O OE2 . GLU A 1 215 ? -28.636 38.396  -15.968 1.00 112.53 ? 215 GLU A OE2 1 
ATOM   1605  N N   . ILE A 1 216 ? -27.139 36.241  -11.026 1.00 141.61 ? 216 ILE A N   1 
ATOM   1606  C CA  . ILE A 1 216 ? -26.723 34.876  -11.365 1.00 136.00 ? 216 ILE A CA  1 
ATOM   1607  C C   . ILE A 1 216 ? -26.641 34.002  -10.104 1.00 133.32 ? 216 ILE A C   1 
ATOM   1608  O O   . ILE A 1 216 ? -26.374 32.809  -10.207 1.00 120.40 ? 216 ILE A O   1 
ATOM   1609  C CB  . ILE A 1 216 ? -25.379 34.882  -12.129 1.00 135.52 ? 216 ILE A CB  1 
ATOM   1610  C CG1 . ILE A 1 216 ? -24.316 35.784  -11.446 1.00 135.68 ? 216 ILE A CG1 1 
ATOM   1611  C CG2 . ILE A 1 216 ? -25.588 35.267  -13.591 1.00 133.08 ? 216 ILE A CG2 1 
ATOM   1612  C CD1 . ILE A 1 216 ? -23.414 35.061  -10.462 1.00 129.24 ? 216 ILE A CD1 1 
ATOM   1613  N N   . GLY A 1 217 ? -26.857 34.605  -8.922  1.00 134.07 ? 217 GLY A N   1 
ATOM   1614  C CA  . GLY A 1 217 ? -26.661 33.915  -7.644  1.00 122.79 ? 217 GLY A CA  1 
ATOM   1615  C C   . GLY A 1 217 ? -27.444 32.598  -7.571  1.00 114.53 ? 217 GLY A C   1 
ATOM   1616  O O   . GLY A 1 217 ? -26.852 31.524  -7.507  1.00 106.13 ? 217 GLY A O   1 
ATOM   1617  N N   . ASP A 1 218 ? -28.783 32.701  -7.573  1.00 110.70 ? 218 ASP A N   1 
ATOM   1618  C CA  . ASP A 1 218 ? -29.648 31.544  -7.408  1.00 101.05 ? 218 ASP A CA  1 
ATOM   1619  C C   . ASP A 1 218 ? -29.648 30.689  -8.682  1.00 90.74  ? 218 ASP A C   1 
ATOM   1620  O O   . ASP A 1 218 ? -29.867 29.486  -8.609  1.00 86.67  ? 218 ASP A O   1 
ATOM   1621  C CB  . ASP A 1 218 ? -31.054 31.956  -7.008  1.00 103.60 ? 218 ASP A CB  1 
ATOM   1622  C CG  . ASP A 1 218 ? -31.141 32.845  -5.779  1.00 104.94 ? 218 ASP A CG  1 
ATOM   1623  O OD1 . ASP A 1 218 ? -30.741 32.390  -4.697  1.00 99.46  ? 218 ASP A OD1 1 
ATOM   1624  O OD2 . ASP A 1 218 ? -31.579 33.992  -5.925  1.00 113.55 ? 218 ASP A OD2 1 
ATOM   1625  N N   . ALA A 1 219 ? -29.402 31.316  -9.848  1.00 83.82  ? 219 ALA A N   1 
ATOM   1626  C CA  . ALA A 1 219 ? -29.504 30.614  -11.134 1.00 84.09  ? 219 ALA A CA  1 
ATOM   1627  C C   . ALA A 1 219 ? -28.429 29.519  -11.235 1.00 93.26  ? 219 ALA A C   1 
ATOM   1628  O O   . ALA A 1 219 ? -28.644 28.497  -11.892 1.00 83.31  ? 219 ALA A O   1 
ATOM   1629  C CB  . ALA A 1 219 ? -29.402 31.599  -12.286 1.00 78.12  ? 219 ALA A CB  1 
ATOM   1630  N N   . PHE A 1 220 ? -27.277 29.748  -10.566 1.00 92.96  ? 220 PHE A N   1 
ATOM   1631  C CA  . PHE A 1 220 ? -26.161 28.801  -10.561 1.00 85.45  ? 220 PHE A CA  1 
ATOM   1632  C C   . PHE A 1 220 ? -26.589 27.473  -9.925  1.00 78.35  ? 220 PHE A C   1 
ATOM   1633  O O   . PHE A 1 220 ? -26.308 26.406  -10.460 1.00 75.07  ? 220 PHE A O   1 
ATOM   1634  C CB  . PHE A 1 220 ? -24.976 29.401  -9.807  1.00 83.64  ? 220 PHE A CB  1 
ATOM   1635  C CG  . PHE A 1 220 ? -23.696 28.605  -9.945  1.00 86.05  ? 220 PHE A CG  1 
ATOM   1636  C CD1 . PHE A 1 220 ? -23.041 28.531  -11.166 1.00 90.90  ? 220 PHE A CD1 1 
ATOM   1637  C CD2 . PHE A 1 220 ? -23.147 27.930  -8.856  1.00 87.05  ? 220 PHE A CD2 1 
ATOM   1638  C CE1 . PHE A 1 220 ? -21.874 27.804  -11.299 1.00 92.03  ? 220 PHE A CE1 1 
ATOM   1639  C CE2 . PHE A 1 220 ? -21.973 27.202  -8.995  1.00 88.79  ? 220 PHE A CE2 1 
ATOM   1640  C CZ  . PHE A 1 220 ? -21.340 27.140  -10.213 1.00 89.75  ? 220 PHE A CZ  1 
ATOM   1641  N N   . VAL A 1 221 ? -27.284 27.556  -8.794  1.00 66.38  ? 221 VAL A N   1 
ATOM   1642  C CA  . VAL A 1 221 ? -27.633 26.377  -8.031  1.00 65.54  ? 221 VAL A CA  1 
ATOM   1643  C C   . VAL A 1 221 ? -28.822 25.672  -8.697  1.00 73.12  ? 221 VAL A C   1 
ATOM   1644  O O   . VAL A 1 221 ? -28.874 24.447  -8.746  1.00 76.95  ? 221 VAL A O   1 
ATOM   1645  C CB  . VAL A 1 221 ? -27.926 26.731  -6.563  1.00 67.04  ? 221 VAL A CB  1 
ATOM   1646  C CG1 . VAL A 1 221 ? -28.050 25.483  -5.691  1.00 72.42  ? 221 VAL A CG1 1 
ATOM   1647  C CG2 . VAL A 1 221 ? -26.871 27.669  -5.981  1.00 69.65  ? 221 VAL A CG2 1 
ATOM   1648  N N   . GLU A 1 222 ? -29.750 26.451  -9.251  1.00 80.66  ? 222 GLU A N   1 
ATOM   1649  C CA  . GLU A 1 222 ? -31.011 25.901  -9.737  1.00 81.48  ? 222 GLU A CA  1 
ATOM   1650  C C   . GLU A 1 222 ? -30.830 25.241  -11.106 1.00 74.66  ? 222 GLU A C   1 
ATOM   1651  O O   . GLU A 1 222 ? -31.714 24.530  -11.553 1.00 77.12  ? 222 GLU A O   1 
ATOM   1652  C CB  . GLU A 1 222 ? -32.108 26.970  -9.811  1.00 96.41  ? 222 GLU A CB  1 
ATOM   1653  C CG  . GLU A 1 222 ? -33.083 26.925  -8.637  1.00 105.47 ? 222 GLU A CG  1 
ATOM   1654  C CD  . GLU A 1 222 ? -34.336 27.765  -8.823  1.00 115.62 ? 222 GLU A CD  1 
ATOM   1655  O OE1 . GLU A 1 222 ? -35.324 27.235  -9.378  1.00 124.05 ? 222 GLU A OE1 1 
ATOM   1656  O OE2 . GLU A 1 222 ? -34.317 28.953  -8.441  1.00 113.22 ? 222 GLU A OE2 1 
ATOM   1657  N N   . HIS A 1 223 ? -29.690 25.498  -11.774 1.00 74.57  ? 223 HIS A N   1 
ATOM   1658  C CA  . HIS A 1 223 ? -29.532 25.153  -13.188 1.00 73.41  ? 223 HIS A CA  1 
ATOM   1659  C C   . HIS A 1 223 ? -29.712 23.641  -13.372 1.00 76.31  ? 223 HIS A C   1 
ATOM   1660  O O   . HIS A 1 223 ? -29.316 22.856  -12.503 1.00 74.38  ? 223 HIS A O   1 
ATOM   1661  C CB  . HIS A 1 223 ? -28.169 25.621  -13.708 1.00 74.74  ? 223 HIS A CB  1 
ATOM   1662  C CG  . HIS A 1 223 ? -28.119 25.823  -15.190 1.00 82.94  ? 223 HIS A CG  1 
ATOM   1663  N ND1 . HIS A 1 223 ? -28.005 24.790  -16.097 1.00 84.53  ? 223 HIS A ND1 1 
ATOM   1664  C CD2 . HIS A 1 223 ? -28.153 26.942  -15.916 1.00 90.99  ? 223 HIS A CD2 1 
ATOM   1665  C CE1 . HIS A 1 223 ? -27.979 25.283  -17.327 1.00 90.53  ? 223 HIS A CE1 1 
ATOM   1666  N NE2 . HIS A 1 223 ? -28.067 26.583  -17.244 1.00 99.46  ? 223 HIS A NE2 1 
ATOM   1667  N N   . PRO A 1 224 ? -30.322 23.187  -14.500 1.00 74.93  ? 224 PRO A N   1 
ATOM   1668  C CA  . PRO A 1 224 ? -30.526 21.747  -14.744 1.00 78.78  ? 224 PRO A CA  1 
ATOM   1669  C C   . PRO A 1 224 ? -29.272 20.905  -15.015 1.00 81.10  ? 224 PRO A C   1 
ATOM   1670  O O   . PRO A 1 224 ? -29.270 19.711  -14.738 1.00 82.31  ? 224 PRO A O   1 
ATOM   1671  C CB  . PRO A 1 224 ? -31.481 21.737  -15.967 1.00 72.44  ? 224 PRO A CB  1 
ATOM   1672  C CG  . PRO A 1 224 ? -31.198 23.045  -16.663 1.00 70.99  ? 224 PRO A CG  1 
ATOM   1673  C CD  . PRO A 1 224 ? -30.944 24.029  -15.532 1.00 68.76  ? 224 PRO A CD  1 
ATOM   1674  N N   . VAL A 1 225 ? -28.216 21.528  -15.566 1.00 81.99  ? 225 VAL A N   1 
ATOM   1675  C CA  . VAL A 1 225 ? -27.078 20.778  -16.112 1.00 81.00  ? 225 VAL A CA  1 
ATOM   1676  C C   . VAL A 1 225 ? -26.265 20.111  -14.985 1.00 73.74  ? 225 VAL A C   1 
ATOM   1677  O O   . VAL A 1 225 ? -25.988 18.918  -15.057 1.00 66.88  ? 225 VAL A O   1 
ATOM   1678  C CB  . VAL A 1 225 ? -26.178 21.647  -17.007 1.00 81.38  ? 225 VAL A CB  1 
ATOM   1679  C CG1 . VAL A 1 225 ? -24.719 21.209  -16.942 1.00 81.62  ? 225 VAL A CG1 1 
ATOM   1680  C CG2 . VAL A 1 225 ? -26.676 21.658  -18.446 1.00 77.17  ? 225 VAL A CG2 1 
ATOM   1681  N N   . PRO A 1 226 ? -25.805 20.848  -13.945 1.00 77.29  ? 226 PRO A N   1 
ATOM   1682  C CA  . PRO A 1 226 ? -24.855 20.278  -12.985 1.00 73.94  ? 226 PRO A CA  1 
ATOM   1683  C C   . PRO A 1 226 ? -25.458 19.101  -12.220 1.00 75.83  ? 226 PRO A C   1 
ATOM   1684  O O   . PRO A 1 226 ? -26.552 19.214  -11.660 1.00 72.68  ? 226 PRO A O   1 
ATOM   1685  C CB  . PRO A 1 226 ? -24.527 21.467  -12.067 1.00 74.45  ? 226 PRO A CB  1 
ATOM   1686  C CG  . PRO A 1 226 ? -25.774 22.330  -12.140 1.00 75.67  ? 226 PRO A CG  1 
ATOM   1687  C CD  . PRO A 1 226 ? -26.211 22.223  -13.598 1.00 75.94  ? 226 PRO A CD  1 
ATOM   1688  N N   . GLY A 1 227 ? -24.725 17.974  -12.201 1.00 69.69  ? 227 GLY A N   1 
ATOM   1689  C CA  . GLY A 1 227 ? -25.110 16.807  -11.418 1.00 59.39  ? 227 GLY A CA  1 
ATOM   1690  C C   . GLY A 1 227 ? -24.919 17.041  -9.916  1.00 61.49  ? 227 GLY A C   1 
ATOM   1691  O O   . GLY A 1 227 ? -25.681 16.531  -9.106  1.00 68.19  ? 227 GLY A O   1 
ATOM   1692  N N   . LEU A 1 228 ? -23.890 17.819  -9.561  1.00 57.72  ? 228 LEU A N   1 
ATOM   1693  C CA  . LEU A 1 228 ? -23.573 18.089  -8.170  1.00 58.12  ? 228 LEU A CA  1 
ATOM   1694  C C   . LEU A 1 228 ? -23.148 19.556  -8.015  1.00 55.23  ? 228 LEU A C   1 
ATOM   1695  O O   . LEU A 1 228 ? -22.563 20.152  -8.932  1.00 55.35  ? 228 LEU A O   1 
ATOM   1696  C CB  . LEU A 1 228 ? -22.473 17.112  -7.735  1.00 56.86  ? 228 LEU A CB  1 
ATOM   1697  C CG  . LEU A 1 228 ? -21.735 17.427  -6.426  1.00 55.62  ? 228 LEU A CG  1 
ATOM   1698  C CD1 . LEU A 1 228 ? -22.543 17.066  -5.212  1.00 59.56  ? 228 LEU A CD1 1 
ATOM   1699  C CD2 . LEU A 1 228 ? -20.384 16.709  -6.383  1.00 57.62  ? 228 LEU A CD2 1 
ATOM   1700  N N   . VAL A 1 229 ? -23.430 20.118  -6.832  1.00 56.98  ? 229 VAL A N   1 
ATOM   1701  C CA  . VAL A 1 229 ? -22.914 21.418  -6.454  1.00 60.11  ? 229 VAL A CA  1 
ATOM   1702  C C   . VAL A 1 229 ? -22.180 21.278  -5.127  1.00 58.77  ? 229 VAL A C   1 
ATOM   1703  O O   . VAL A 1 229 ? -22.672 20.632  -4.205  1.00 57.57  ? 229 VAL A O   1 
ATOM   1704  C CB  . VAL A 1 229 ? -24.019 22.485  -6.366  1.00 66.49  ? 229 VAL A CB  1 
ATOM   1705  C CG1 . VAL A 1 229 ? -23.444 23.849  -6.001  1.00 74.95  ? 229 VAL A CG1 1 
ATOM   1706  C CG2 . VAL A 1 229 ? -24.825 22.576  -7.656  1.00 66.66  ? 229 VAL A CG2 1 
ATOM   1707  N N   . THR A 1 230 ? -20.997 21.906  -5.044  1.00 61.47  ? 230 THR A N   1 
ATOM   1708  C CA  . THR A 1 230 ? -20.151 21.815  -3.864  1.00 66.29  ? 230 THR A CA  1 
ATOM   1709  C C   . THR A 1 230 ? -19.924 23.213  -3.317  1.00 64.48  ? 230 THR A C   1 
ATOM   1710  O O   . THR A 1 230 ? -19.738 24.149  -4.082  1.00 61.76  ? 230 THR A O   1 
ATOM   1711  C CB  . THR A 1 230 ? -18.823 21.121  -4.216  1.00 64.18  ? 230 THR A CB  1 
ATOM   1712  O OG1 . THR A 1 230 ? -18.172 21.915  -5.206  1.00 60.02  ? 230 THR A OG1 1 
ATOM   1713  C CG2 . THR A 1 230 ? -19.030 19.708  -4.745  1.00 60.68  ? 230 THR A CG2 1 
ATOM   1714  N N   . PHE A 1 231 ? -19.908 23.328  -1.983  1.00 69.46  ? 231 PHE A N   1 
ATOM   1715  C CA  . PHE A 1 231 ? -19.697 24.602  -1.321  1.00 75.85  ? 231 PHE A CA  1 
ATOM   1716  C C   . PHE A 1 231 ? -19.077 24.363  0.052   1.00 77.23  ? 231 PHE A C   1 
ATOM   1717  O O   . PHE A 1 231 ? -19.558 23.529  0.811   1.00 73.94  ? 231 PHE A O   1 
ATOM   1718  C CB  . PHE A 1 231 ? -21.016 25.379  -1.180  1.00 82.83  ? 231 PHE A CB  1 
ATOM   1719  C CG  . PHE A 1 231 ? -20.964 26.482  -0.131  1.00 86.57  ? 231 PHE A CG  1 
ATOM   1720  C CD1 . PHE A 1 231 ? -20.580 27.779  -0.470  1.00 85.14  ? 231 PHE A CD1 1 
ATOM   1721  C CD2 . PHE A 1 231 ? -21.251 26.209  1.200   1.00 89.20  ? 231 PHE A CD2 1 
ATOM   1722  C CE1 . PHE A 1 231 ? -20.517 28.771  0.487   1.00 85.44  ? 231 PHE A CE1 1 
ATOM   1723  C CE2 . PHE A 1 231 ? -21.172 27.205  2.157   1.00 93.55  ? 231 PHE A CE2 1 
ATOM   1724  C CZ  . PHE A 1 231 ? -20.812 28.486  1.798   1.00 94.53  ? 231 PHE A CZ  1 
ATOM   1725  N N   . THR A 1 232 ? -18.027 25.143  0.364   1.00 77.95  ? 232 THR A N   1 
ATOM   1726  C CA  . THR A 1 232 ? -17.465 25.230  1.710   1.00 83.87  ? 232 THR A CA  1 
ATOM   1727  C C   . THR A 1 232 ? -17.379 26.720  2.104   1.00 92.12  ? 232 THR A C   1 
ATOM   1728  O O   . THR A 1 232 ? -16.822 27.515  1.361   1.00 102.69 ? 232 THR A O   1 
ATOM   1729  C CB  . THR A 1 232 ? -16.080 24.561  1.730   1.00 88.99  ? 232 THR A CB  1 
ATOM   1730  O OG1 . THR A 1 232 ? -16.203 23.248  1.187   1.00 90.46  ? 232 THR A OG1 1 
ATOM   1731  C CG2 . THR A 1 232 ? -15.500 24.449  3.128   1.00 89.13  ? 232 THR A CG2 1 
ATOM   1732  N N   . GLY A 1 233 ? -17.950 27.087  3.271   1.00 87.24  ? 233 GLY A N   1 
ATOM   1733  C CA  . GLY A 1 233 ? -17.958 28.484  3.715   1.00 86.00  ? 233 GLY A CA  1 
ATOM   1734  C C   . GLY A 1 233 ? -18.928 28.715  4.882   1.00 87.29  ? 233 GLY A C   1 
ATOM   1735  O O   . GLY A 1 233 ? -19.034 27.888  5.778   1.00 83.93  ? 233 GLY A O   1 
ATOM   1736  N N   . SER A 1 234 ? -19.596 29.886  4.888   1.00 101.41 ? 234 SER A N   1 
ATOM   1737  C CA  . SER A 1 234 ? -20.490 30.242  5.987   1.00 110.25 ? 234 SER A CA  1 
ATOM   1738  C C   . SER A 1 234 ? -21.653 29.268  6.036   1.00 106.49 ? 234 SER A C   1 
ATOM   1739  O O   . SER A 1 234 ? -22.138 28.797  4.995   1.00 108.79 ? 234 SER A O   1 
ATOM   1740  C CB  . SER A 1 234 ? -21.009 31.683  5.898   1.00 119.90 ? 234 SER A CB  1 
ATOM   1741  O OG  . SER A 1 234 ? -19.956 32.615  5.689   1.00 131.15 ? 234 SER A OG  1 
ATOM   1742  N N   . THR A 1 235 ? -22.090 28.994  7.263   1.00 108.75 ? 235 THR A N   1 
ATOM   1743  C CA  . THR A 1 235 ? -23.338 28.304  7.531   1.00 110.33 ? 235 THR A CA  1 
ATOM   1744  C C   . THR A 1 235 ? -24.520 29.083  6.916   1.00 106.81 ? 235 THR A C   1 
ATOM   1745  O O   . THR A 1 235 ? -25.302 28.498  6.179   1.00 109.18 ? 235 THR A O   1 
ATOM   1746  C CB  . THR A 1 235 ? -23.486 28.108  9.048   1.00 113.45 ? 235 THR A CB  1 
ATOM   1747  O OG1 . THR A 1 235 ? -22.432 27.223  9.432   1.00 114.05 ? 235 THR A OG1 1 
ATOM   1748  C CG2 . THR A 1 235 ? -24.838 27.533  9.439   1.00 109.00 ? 235 THR A CG2 1 
ATOM   1749  N N   . PRO A 1 236 ? -24.720 30.409  7.208   1.00 110.20 ? 236 PRO A N   1 
ATOM   1750  C CA  . PRO A 1 236 ? -25.861 31.141  6.646   1.00 106.20 ? 236 PRO A CA  1 
ATOM   1751  C C   . PRO A 1 236 ? -25.871 31.134  5.119   1.00 94.05  ? 236 PRO A C   1 
ATOM   1752  O O   . PRO A 1 236 ? -26.915 30.937  4.509   1.00 81.64  ? 236 PRO A O   1 
ATOM   1753  C CB  . PRO A 1 236 ? -25.714 32.569  7.232   1.00 104.62 ? 236 PRO A CB  1 
ATOM   1754  C CG  . PRO A 1 236 ? -24.903 32.361  8.499   1.00 104.91 ? 236 PRO A CG  1 
ATOM   1755  C CD  . PRO A 1 236 ? -23.934 31.234  8.143   1.00 111.22 ? 236 PRO A CD  1 
ATOM   1756  N N   . VAL A 1 237 ? -24.690 31.325  4.514   1.00 92.27  ? 237 VAL A N   1 
ATOM   1757  C CA  . VAL A 1 237 ? -24.570 31.361  3.065   1.00 98.49  ? 237 VAL A CA  1 
ATOM   1758  C C   . VAL A 1 237 ? -24.868 29.973  2.508   1.00 104.31 ? 237 VAL A C   1 
ATOM   1759  O O   . VAL A 1 237 ? -25.653 29.835  1.573   1.00 107.35 ? 237 VAL A O   1 
ATOM   1760  C CB  . VAL A 1 237 ? -23.187 31.852  2.610   1.00 106.16 ? 237 VAL A CB  1 
ATOM   1761  C CG1 . VAL A 1 237 ? -22.890 31.456  1.164   1.00 107.23 ? 237 VAL A CG1 1 
ATOM   1762  C CG2 . VAL A 1 237 ? -23.035 33.358  2.802   1.00 109.64 ? 237 VAL A CG2 1 
ATOM   1763  N N   . GLY A 1 238 ? -24.228 28.953  3.089   1.00 103.76 ? 238 GLY A N   1 
ATOM   1764  C CA  . GLY A 1 238 ? -24.412 27.576  2.646   1.00 107.92 ? 238 GLY A CA  1 
ATOM   1765  C C   . GLY A 1 238 ? -25.850 27.094  2.874   1.00 103.07 ? 238 GLY A C   1 
ATOM   1766  O O   . GLY A 1 238 ? -26.415 26.362  2.051   1.00 101.25 ? 238 GLY A O   1 
ATOM   1767  N N   . ARG A 1 239 ? -26.420 27.506  4.006   1.00 98.98  ? 239 ARG A N   1 
ATOM   1768  C CA  . ARG A 1 239 ? -27.779 27.152  4.373   1.00 98.84  ? 239 ARG A CA  1 
ATOM   1769  C C   . ARG A 1 239 ? -28.736 27.589  3.271   1.00 93.85  ? 239 ARG A C   1 
ATOM   1770  O O   . ARG A 1 239 ? -29.667 26.865  2.922   1.00 86.86  ? 239 ARG A O   1 
ATOM   1771  C CB  . ARG A 1 239 ? -28.142 27.868  5.670   1.00 106.42 ? 239 ARG A CB  1 
ATOM   1772  N N   . ASN A 1 240 ? -28.515 28.808  2.773   1.00 97.91  ? 240 ASN A N   1 
ATOM   1773  C CA  . ASN A 1 240 ? -29.314 29.382  1.709   1.00 108.89 ? 240 ASN A CA  1 
ATOM   1774  C C   . ASN A 1 240 ? -29.245 28.479  0.477   1.00 103.71 ? 240 ASN A C   1 
ATOM   1775  O O   . ASN A 1 240 ? -30.272 28.168  -0.126  1.00 104.34 ? 240 ASN A O   1 
ATOM   1776  C CB  . ASN A 1 240 ? -28.866 30.812  1.399   1.00 117.16 ? 240 ASN A CB  1 
ATOM   1777  C CG  . ASN A 1 240 ? -29.937 31.612  0.698   1.00 122.28 ? 240 ASN A CG  1 
ATOM   1778  O OD1 . ASN A 1 240 ? -30.991 31.889  1.288   1.00 133.76 ? 240 ASN A OD1 1 
ATOM   1779  N ND2 . ASN A 1 240 ? -29.689 32.002  -0.547  1.00 108.64 ? 240 ASN A ND2 1 
ATOM   1780  N N   . ILE A 1 241 ? -28.021 28.063  0.117   1.00 101.49 ? 241 ILE A N   1 
ATOM   1781  C CA  . ILE A 1 241 ? -27.797 27.239  -1.067  1.00 102.29 ? 241 ILE A CA  1 
ATOM   1782  C C   . ILE A 1 241 ? -28.671 25.986  -0.976  1.00 92.99  ? 241 ILE A C   1 
ATOM   1783  O O   . ILE A 1 241 ? -29.200 25.523  -1.988  1.00 73.35  ? 241 ILE A O   1 
ATOM   1784  C CB  . ILE A 1 241 ? -26.298 26.907  -1.225  1.00 105.54 ? 241 ILE A CB  1 
ATOM   1785  C CG1 . ILE A 1 241 ? -25.525 28.102  -1.795  1.00 110.67 ? 241 ILE A CG1 1 
ATOM   1786  C CG2 . ILE A 1 241 ? -26.088 25.650  -2.072  1.00 103.10 ? 241 ILE A CG2 1 
ATOM   1787  C CD1 . ILE A 1 241 ? -24.162 28.317  -1.166  1.00 108.56 ? 241 ILE A CD1 1 
ATOM   1788  N N   . GLY A 1 242 ? -28.861 25.492  0.260   1.00 92.93  ? 242 GLY A N   1 
ATOM   1789  C CA  . GLY A 1 242 ? -29.656 24.300  0.523   1.00 99.73  ? 242 GLY A CA  1 
ATOM   1790  C C   . GLY A 1 242 ? -31.078 24.406  -0.039  1.00 103.96 ? 242 GLY A C   1 
ATOM   1791  O O   . GLY A 1 242 ? -31.556 23.472  -0.692  1.00 111.20 ? 242 GLY A O   1 
ATOM   1792  N N   . ARG A 1 243 ? -31.771 25.521  0.261   1.00 102.70 ? 243 ARG A N   1 
ATOM   1793  C CA  . ARG A 1 243 ? -33.157 25.678  -0.167  1.00 99.41  ? 243 ARG A CA  1 
ATOM   1794  C C   . ARG A 1 243 ? -33.213 25.758  -1.674  1.00 88.16  ? 243 ARG A C   1 
ATOM   1795  O O   . ARG A 1 243 ? -34.131 25.237  -2.289  1.00 102.62 ? 243 ARG A O   1 
ATOM   1796  C CB  . ARG A 1 243 ? -33.863 26.954  0.271   1.00 109.45 ? 243 ARG A CB  1 
ATOM   1797  N N   . ILE A 1 244 ? -32.297 26.519  -2.256  1.00 80.79  ? 244 ILE A N   1 
ATOM   1798  C CA  . ILE A 1 244 ? -32.333 26.725  -3.685  1.00 81.59  ? 244 ILE A CA  1 
ATOM   1799  C C   . ILE A 1 244 ? -32.321 25.353  -4.348  1.00 80.97  ? 244 ILE A C   1 
ATOM   1800  O O   . ILE A 1 244 ? -33.082 25.115  -5.286  1.00 77.75  ? 244 ILE A O   1 
ATOM   1801  C CB  . ILE A 1 244 ? -31.185 27.620  -4.184  1.00 85.08  ? 244 ILE A CB  1 
ATOM   1802  C CG1 . ILE A 1 244 ? -30.767 28.665  -3.148  1.00 96.13  ? 244 ILE A CG1 1 
ATOM   1803  C CG2 . ILE A 1 244 ? -31.563 28.267  -5.514  1.00 82.80  ? 244 ILE A CG2 1 
ATOM   1804  C CD1 . ILE A 1 244 ? -29.673 29.613  -3.622  1.00 100.53 ? 244 ILE A CD1 1 
ATOM   1805  N N   . ALA A 1 245 ? -31.526 24.419  -3.779  1.00 73.83  ? 245 ALA A N   1 
ATOM   1806  C CA  . ALA A 1 245 ? -31.436 23.067  -4.311  1.00 76.35  ? 245 ALA A CA  1 
ATOM   1807  C C   . ALA A 1 245 ? -32.810 22.424  -4.323  1.00 77.61  ? 245 ALA A C   1 
ATOM   1808  O O   . ALA A 1 245 ? -33.315 22.060  -5.383  1.00 88.57  ? 245 ALA A O   1 
ATOM   1809  C CB  . ALA A 1 245 ? -30.451 22.247  -3.515  1.00 85.14  ? 245 ALA A CB  1 
ATOM   1810  N N   . SER A 1 246 ? -33.413 22.284  -3.141  1.00 83.37  ? 246 SER A N   1 
ATOM   1811  C CA  . SER A 1 246 ? -34.664 21.546  -3.033  1.00 92.54  ? 246 SER A CA  1 
ATOM   1812  C C   . SER A 1 246 ? -35.854 22.456  -3.387  1.00 94.08  ? 246 SER A C   1 
ATOM   1813  O O   . SER A 1 246 ? -36.893 21.967  -3.801  1.00 101.63 ? 246 SER A O   1 
ATOM   1814  C CB  . SER A 1 246 ? -34.819 20.879  -1.664  1.00 88.69  ? 246 SER A CB  1 
ATOM   1815  O OG  . SER A 1 246 ? -34.471 21.751  -0.600  1.00 91.51  ? 246 SER A OG  1 
ATOM   1816  N N   . GLY A 1 247 ? -35.647 23.784  -3.319  1.00 102.05 ? 247 GLY A N   1 
ATOM   1817  C CA  . GLY A 1 247 ? -36.682 24.762  -3.659  1.00 94.98  ? 247 GLY A CA  1 
ATOM   1818  C C   . GLY A 1 247 ? -36.989 24.780  -5.163  1.00 98.81  ? 247 GLY A C   1 
ATOM   1819  O O   . GLY A 1 247 ? -38.124 25.005  -5.562  1.00 102.71 ? 247 GLY A O   1 
ATOM   1820  N N   . GLY A 1 248 ? -35.971 24.529  -5.991  1.00 96.81  ? 248 GLY A N   1 
ATOM   1821  C CA  . GLY A 1 248 ? -36.115 24.669  -7.439  1.00 98.66  ? 248 GLY A CA  1 
ATOM   1822  C C   . GLY A 1 248 ? -36.930 23.526  -8.050  1.00 101.57 ? 248 GLY A C   1 
ATOM   1823  O O   . GLY A 1 248 ? -37.177 22.514  -7.401  1.00 115.57 ? 248 GLY A O   1 
ATOM   1824  N N   . ALA A 1 249 ? -37.279 23.677  -9.336  1.00 102.34 ? 249 ALA A N   1 
ATOM   1825  C CA  . ALA A 1 249 ? -38.132 22.714  -10.031 1.00 98.63  ? 249 ALA A CA  1 
ATOM   1826  C C   . ALA A 1 249 ? -37.437 21.341  -10.138 1.00 101.27 ? 249 ALA A C   1 
ATOM   1827  O O   . ALA A 1 249 ? -38.008 20.336  -9.766  1.00 94.65  ? 249 ALA A O   1 
ATOM   1828  C CB  . ALA A 1 249 ? -38.528 23.258  -11.385 1.00 96.19  ? 249 ALA A CB  1 
ATOM   1829  N N   . HIS A 1 250 ? -36.188 21.303  -10.600 1.00 109.73 ? 250 HIS A N   1 
ATOM   1830  C CA  . HIS A 1 250 ? -35.437 20.054  -10.557 1.00 116.66 ? 250 HIS A CA  1 
ATOM   1831  C C   . HIS A 1 250 ? -34.703 19.930  -9.218  1.00 111.86 ? 250 HIS A C   1 
ATOM   1832  O O   . HIS A 1 250 ? -34.344 20.935  -8.587  1.00 109.57 ? 250 HIS A O   1 
ATOM   1833  C CB  . HIS A 1 250 ? -34.455 19.936  -11.723 1.00 121.64 ? 250 HIS A CB  1 
ATOM   1834  C CG  . HIS A 1 250 ? -35.042 20.056  -13.092 1.00 120.74 ? 250 HIS A CG  1 
ATOM   1835  N ND1 . HIS A 1 250 ? -36.248 20.652  -13.371 1.00 119.50 ? 250 HIS A ND1 1 
ATOM   1836  C CD2 . HIS A 1 250 ? -34.545 19.653  -14.275 1.00 120.45 ? 250 HIS A CD2 1 
ATOM   1837  C CE1 . HIS A 1 250 ? -36.462 20.610  -14.676 1.00 121.89 ? 250 HIS A CE1 1 
ATOM   1838  N NE2 . HIS A 1 250 ? -35.440 20.008  -15.243 1.00 124.01 ? 250 HIS A NE2 1 
ATOM   1839  N N   . LEU A 1 251 ? -34.417 18.682  -8.845  1.00 99.50  ? 251 LEU A N   1 
ATOM   1840  C CA  . LEU A 1 251 ? -33.736 18.361  -7.596  1.00 100.65 ? 251 LEU A CA  1 
ATOM   1841  C C   . LEU A 1 251 ? -32.255 18.086  -7.893  1.00 100.13 ? 251 LEU A C   1 
ATOM   1842  O O   . LEU A 1 251 ? -31.940 17.297  -8.783  1.00 96.88  ? 251 LEU A O   1 
ATOM   1843  C CB  . LEU A 1 251 ? -34.421 17.148  -6.937  1.00 107.97 ? 251 LEU A CB  1 
ATOM   1844  C CG  . LEU A 1 251 ? -34.576 15.882  -7.808  1.00 114.31 ? 251 LEU A CG  1 
ATOM   1845  C CD1 . LEU A 1 251 ? -34.657 14.637  -6.926  1.00 112.71 ? 251 LEU A CD1 1 
ATOM   1846  C CD2 . LEU A 1 251 ? -35.799 15.943  -8.753  1.00 107.62 ? 251 LEU A CD2 1 
ATOM   1847  N N   . LYS A 1 252 ? -31.354 18.741  -7.136  1.00 93.96  ? 252 LYS A N   1 
ATOM   1848  C CA  . LYS A 1 252 ? -29.916 18.660  -7.396  1.00 90.99  ? 252 LYS A CA  1 
ATOM   1849  C C   . LYS A 1 252 ? -29.205 18.096  -6.171  1.00 93.07  ? 252 LYS A C   1 
ATOM   1850  O O   . LYS A 1 252 ? -29.544 18.449  -5.046  1.00 102.01 ? 252 LYS A O   1 
ATOM   1851  C CB  . LYS A 1 252 ? -29.373 20.050  -7.748  1.00 91.95  ? 252 LYS A CB  1 
ATOM   1852  C CG  . LYS A 1 252 ? -29.943 20.635  -9.015  1.00 91.59  ? 252 LYS A CG  1 
ATOM   1853  C CD  . LYS A 1 252 ? -29.378 19.987  -10.273 1.00 100.75 ? 252 LYS A CD  1 
ATOM   1854  C CE  . LYS A 1 252 ? -30.437 19.640  -11.286 1.00 103.18 ? 252 LYS A CE  1 
ATOM   1855  N NZ  . LYS A 1 252 ? -30.184 18.352  -11.946 1.00 96.02  ? 252 LYS A NZ  1 
ATOM   1856  N N   . HIS A 1 253 ? -28.213 17.218  -6.402  1.00 84.58  ? 253 HIS A N   1 
ATOM   1857  C CA  . HIS A 1 253 ? -27.317 16.783  -5.335  1.00 82.00  ? 253 HIS A CA  1 
ATOM   1858  C C   . HIS A 1 253 ? -26.404 17.943  -4.928  1.00 72.41  ? 253 HIS A C   1 
ATOM   1859  O O   . HIS A 1 253 ? -25.868 18.653  -5.780  1.00 75.82  ? 253 HIS A O   1 
ATOM   1860  C CB  . HIS A 1 253 ? -26.502 15.555  -5.758  1.00 91.01  ? 253 HIS A CB  1 
ATOM   1861  C CG  . HIS A 1 253 ? -27.209 14.252  -5.551  1.00 108.82 ? 253 HIS A CG  1 
ATOM   1862  N ND1 . HIS A 1 253 ? -26.696 13.247  -4.751  1.00 111.43 ? 253 HIS A ND1 1 
ATOM   1863  C CD2 . HIS A 1 253 ? -28.400 13.801  -5.996  1.00 115.29 ? 253 HIS A CD2 1 
ATOM   1864  C CE1 . HIS A 1 253 ? -27.545 12.224  -4.730  1.00 113.22 ? 253 HIS A CE1 1 
ATOM   1865  N NE2 . HIS A 1 253 ? -28.584 12.534  -5.483  1.00 112.21 ? 253 HIS A NE2 1 
ATOM   1866  N N   . VAL A 1 254 ? -26.232 18.123  -3.621  1.00 67.74  ? 254 VAL A N   1 
ATOM   1867  C CA  . VAL A 1 254 ? -25.395 19.185  -3.097  1.00 70.46  ? 254 VAL A CA  1 
ATOM   1868  C C   . VAL A 1 254 ? -24.495 18.603  -2.020  1.00 68.90  ? 254 VAL A C   1 
ATOM   1869  O O   . VAL A 1 254 ? -24.955 17.847  -1.172  1.00 75.03  ? 254 VAL A O   1 
ATOM   1870  C CB  . VAL A 1 254 ? -26.229 20.361  -2.547  1.00 76.35  ? 254 VAL A CB  1 
ATOM   1871  C CG1 . VAL A 1 254 ? -25.353 21.447  -1.934  1.00 82.63  ? 254 VAL A CG1 1 
ATOM   1872  C CG2 . VAL A 1 254 ? -27.130 20.962  -3.613  1.00 81.89  ? 254 VAL A CG2 1 
ATOM   1873  N N   . ALA A 1 255 ? -23.214 19.000  -2.051  1.00 66.52  ? 255 ALA A N   1 
ATOM   1874  C CA  . ALA A 1 255 ? -22.248 18.624  -1.029  1.00 66.76  ? 255 ALA A CA  1 
ATOM   1875  C C   . ALA A 1 255 ? -21.885 19.852  -0.186  1.00 71.92  ? 255 ALA A C   1 
ATOM   1876  O O   . ALA A 1 255 ? -21.282 20.802  -0.689  1.00 80.97  ? 255 ALA A O   1 
ATOM   1877  C CB  . ALA A 1 255 ? -21.025 18.011  -1.688  1.00 68.29  ? 255 ALA A CB  1 
ATOM   1878  N N   . LEU A 1 256 ? -22.250 19.817  1.106   1.00 74.03  ? 256 LEU A N   1 
ATOM   1879  C CA  . LEU A 1 256 ? -22.222 21.011  1.937   1.00 81.28  ? 256 LEU A CA  1 
ATOM   1880  C C   . LEU A 1 256 ? -21.281 20.822  3.128   1.00 90.65  ? 256 LEU A C   1 
ATOM   1881  O O   . LEU A 1 256 ? -21.489 19.948  3.973   1.00 89.14  ? 256 LEU A O   1 
ATOM   1882  C CB  . LEU A 1 256 ? -23.633 21.368  2.375   1.00 75.82  ? 256 LEU A CB  1 
ATOM   1883  C CG  . LEU A 1 256 ? -24.457 22.116  1.333   1.00 72.00  ? 256 LEU A CG  1 
ATOM   1884  C CD1 . LEU A 1 256 ? -25.897 22.161  1.745   1.00 68.82  ? 256 LEU A CD1 1 
ATOM   1885  C CD2 . LEU A 1 256 ? -23.903 23.537  1.103   1.00 74.56  ? 256 LEU A CD2 1 
ATOM   1886  N N   . GLU A 1 257 ? -20.265 21.702  3.173   1.00 98.52  ? 257 GLU A N   1 
ATOM   1887  C CA  . GLU A 1 257 ? -19.247 21.745  4.214   1.00 106.02 ? 257 GLU A CA  1 
ATOM   1888  C C   . GLU A 1 257 ? -19.368 23.073  4.974   1.00 105.24 ? 257 GLU A C   1 
ATOM   1889  O O   . GLU A 1 257 ? -18.826 24.072  4.525   1.00 102.91 ? 257 GLU A O   1 
ATOM   1890  C CB  . GLU A 1 257 ? -17.860 21.732  3.554   1.00 112.24 ? 257 GLU A CB  1 
ATOM   1891  C CG  . GLU A 1 257 ? -17.432 20.370  3.001   1.00 120.72 ? 257 GLU A CG  1 
ATOM   1892  C CD  . GLU A 1 257 ? -18.406 19.795  1.991   1.00 127.01 ? 257 GLU A CD  1 
ATOM   1893  O OE1 . GLU A 1 257 ? -18.874 18.661  2.217   1.00 131.50 ? 257 GLU A OE1 1 
ATOM   1894  O OE2 . GLU A 1 257 ? -18.691 20.468  0.975   1.00 133.57 ? 257 GLU A OE2 1 
ATOM   1895  N N   . LEU A 1 258 ? -20.111 23.091  6.103   1.00 100.78 ? 258 LEU A N   1 
ATOM   1896  C CA  . LEU A 1 258 ? -20.479 24.360  6.751   1.00 96.60  ? 258 LEU A CA  1 
ATOM   1897  C C   . LEU A 1 258 ? -19.603 24.596  7.984   1.00 102.27 ? 258 LEU A C   1 
ATOM   1898  O O   . LEU A 1 258 ? -19.555 23.764  8.885   1.00 91.47  ? 258 LEU A O   1 
ATOM   1899  C CB  . LEU A 1 258 ? -21.962 24.393  7.126   1.00 90.64  ? 258 LEU A CB  1 
ATOM   1900  C CG  . LEU A 1 258 ? -22.967 24.265  5.971   1.00 87.98  ? 258 LEU A CG  1 
ATOM   1901  C CD1 . LEU A 1 258 ? -24.331 24.838  6.364   1.00 88.16  ? 258 LEU A CD1 1 
ATOM   1902  C CD2 . LEU A 1 258 ? -22.462 24.921  4.702   1.00 80.76  ? 258 LEU A CD2 1 
ATOM   1903  N N   . GLY A 1 259 ? -18.990 25.791  8.047   1.00 109.93 ? 259 GLY A N   1 
ATOM   1904  C CA  . GLY A 1 259 ? -18.084 26.150  9.127   1.00 111.13 ? 259 GLY A CA  1 
ATOM   1905  C C   . GLY A 1 259 ? -18.821 26.268  10.459  1.00 115.74 ? 259 GLY A C   1 
ATOM   1906  O O   . GLY A 1 259 ? -20.022 26.543  10.492  1.00 117.59 ? 259 GLY A O   1 
ATOM   1907  N N   . GLY A 1 260 ? -18.085 26.050  11.552  1.00 110.97 ? 260 GLY A N   1 
ATOM   1908  C CA  . GLY A 1 260 ? -18.671 26.059  12.882  1.00 109.49 ? 260 GLY A CA  1 
ATOM   1909  C C   . GLY A 1 260 ? -17.697 26.576  13.950  1.00 110.02 ? 260 GLY A C   1 
ATOM   1910  O O   . GLY A 1 260 ? -16.505 26.768  13.702  1.00 98.40  ? 260 GLY A O   1 
ATOM   1911  N N   . ASN A 1 261 ? -18.234 26.772  15.153  1.00 106.09 ? 261 ASN A N   1 
ATOM   1912  C CA  . ASN A 1 261 ? -17.443 27.107  16.324  1.00 104.47 ? 261 ASN A CA  1 
ATOM   1913  C C   . ASN A 1 261 ? -16.741 25.839  16.835  1.00 97.92  ? 261 ASN A C   1 
ATOM   1914  O O   . ASN A 1 261 ? -17.404 24.907  17.288  1.00 88.41  ? 261 ASN A O   1 
ATOM   1915  C CB  . ASN A 1 261 ? -18.331 27.727  17.400  1.00 104.17 ? 261 ASN A CB  1 
ATOM   1916  C CG  . ASN A 1 261 ? -17.627 28.805  18.183  1.00 106.12 ? 261 ASN A CG  1 
ATOM   1917  O OD1 . ASN A 1 261 ? -16.899 28.513  19.139  1.00 97.81  ? 261 ASN A OD1 1 
ATOM   1918  N ND2 . ASN A 1 261 ? -17.871 30.060  17.828  1.00 113.55 ? 261 ASN A ND2 1 
ATOM   1919  N N   . SER A 1 262 ? -15.396 25.816  16.762  1.00 81.36  ? 262 SER A N   1 
ATOM   1920  C CA  . SER A 1 262 ? -14.631 24.612  17.089  1.00 73.08  ? 262 SER A CA  1 
ATOM   1921  C C   . SER A 1 262 ? -13.950 24.768  18.451  1.00 66.60  ? 262 SER A C   1 
ATOM   1922  O O   . SER A 1 262 ? -13.220 25.726  18.684  1.00 62.01  ? 262 SER A O   1 
ATOM   1923  C CB  . SER A 1 262 ? -13.641 24.290  16.011  1.00 75.11  ? 262 SER A CB  1 
ATOM   1924  O OG  . SER A 1 262 ? -14.308 23.759  14.869  1.00 74.87  ? 262 SER A OG  1 
ATOM   1925  N N   . PRO A 1 263 ? -14.203 23.850  19.408  1.00 62.49  ? 263 PRO A N   1 
ATOM   1926  C CA  . PRO A 1 263 ? -13.728 24.028  20.774  1.00 60.30  ? 263 PRO A CA  1 
ATOM   1927  C C   . PRO A 1 263 ? -12.346 23.439  21.047  1.00 62.24  ? 263 PRO A C   1 
ATOM   1928  O O   . PRO A 1 263 ? -12.050 22.318  20.646  1.00 64.25  ? 263 PRO A O   1 
ATOM   1929  C CB  . PRO A 1 263 ? -14.833 23.330  21.605  1.00 65.35  ? 263 PRO A CB  1 
ATOM   1930  C CG  . PRO A 1 263 ? -15.369 22.224  20.680  1.00 64.96  ? 263 PRO A CG  1 
ATOM   1931  C CD  . PRO A 1 263 ? -15.063 22.671  19.250  1.00 63.66  ? 263 PRO A CD  1 
ATOM   1932  N N   . PHE A 1 264 ? -11.530 24.211  21.777  1.00 61.59  ? 264 PHE A N   1 
ATOM   1933  C CA  . PHE A 1 264 ? -10.202 23.802  22.188  1.00 56.63  ? 264 PHE A CA  1 
ATOM   1934  C C   . PHE A 1 264 ? -10.231 23.526  23.681  1.00 57.88  ? 264 PHE A C   1 
ATOM   1935  O O   . PHE A 1 264 ? -10.391 24.456  24.476  1.00 68.68  ? 264 PHE A O   1 
ATOM   1936  C CB  . PHE A 1 264 ? -9.241  24.946  21.815  1.00 60.80  ? 264 PHE A CB  1 
ATOM   1937  C CG  . PHE A 1 264 ? -7.766  24.612  21.927  1.00 56.10  ? 264 PHE A CG  1 
ATOM   1938  C CD1 . PHE A 1 264 ? -7.110  24.674  23.153  1.00 56.77  ? 264 PHE A CD1 1 
ATOM   1939  C CD2 . PHE A 1 264 ? -7.039  24.227  20.808  1.00 51.74  ? 264 PHE A CD2 1 
ATOM   1940  C CE1 . PHE A 1 264 ? -5.774  24.359  23.251  1.00 54.16  ? 264 PHE A CE1 1 
ATOM   1941  C CE2 . PHE A 1 264 ? -5.704  23.898  20.913  1.00 48.52  ? 264 PHE A CE2 1 
ATOM   1942  C CZ  . PHE A 1 264 ? -5.073  23.961  22.131  1.00 53.99  ? 264 PHE A CZ  1 
ATOM   1943  N N   . VAL A 1 265 ? -10.107 22.246  24.061  1.00 52.76  ? 265 VAL A N   1 
ATOM   1944  C CA  . VAL A 1 265 ? -10.372 21.839  25.427  1.00 50.94  ? 265 VAL A CA  1 
ATOM   1945  C C   . VAL A 1 265 ? -9.054  21.475  26.103  1.00 61.38  ? 265 VAL A C   1 
ATOM   1946  O O   . VAL A 1 265 ? -8.270  20.684  25.565  1.00 62.73  ? 265 VAL A O   1 
ATOM   1947  C CB  . VAL A 1 265 ? -11.384 20.686  25.512  1.00 56.59  ? 265 VAL A CB  1 
ATOM   1948  C CG1 . VAL A 1 265 ? -11.590 20.218  26.957  1.00 55.11  ? 265 VAL A CG1 1 
ATOM   1949  C CG2 . VAL A 1 265 ? -12.730 21.057  24.868  1.00 60.03  ? 265 VAL A CG2 1 
ATOM   1950  N N   . VAL A 1 266 ? -8.831  22.057  27.305  1.00 68.14  ? 266 VAL A N   1 
ATOM   1951  C CA  . VAL A 1 266 ? -7.612  21.825  28.066  1.00 70.03  ? 266 VAL A CA  1 
ATOM   1952  C C   . VAL A 1 266 ? -7.971  21.191  29.413  1.00 62.26  ? 266 VAL A C   1 
ATOM   1953  O O   . VAL A 1 266 ? -8.552  21.826  30.266  1.00 58.89  ? 266 VAL A O   1 
ATOM   1954  C CB  . VAL A 1 266 ? -6.819  23.129  28.251  1.00 67.90  ? 266 VAL A CB  1 
ATOM   1955  C CG1 . VAL A 1 266 ? -5.433  22.858  28.845  1.00 64.27  ? 266 VAL A CG1 1 
ATOM   1956  C CG2 . VAL A 1 266 ? -6.708  23.915  26.939  1.00 66.92  ? 266 VAL A CG2 1 
ATOM   1957  N N   . LEU A 1 267 ? -7.617  19.925  29.579  1.00 67.66  ? 267 LEU A N   1 
ATOM   1958  C CA  . LEU A 1 267 ? -7.898  19.204  30.815  1.00 75.35  ? 267 LEU A CA  1 
ATOM   1959  C C   . LEU A 1 267 ? -6.834  19.547  31.860  1.00 73.49  ? 267 LEU A C   1 
ATOM   1960  O O   . LEU A 1 267 ? -5.795  20.118  31.539  1.00 79.87  ? 267 LEU A O   1 
ATOM   1961  C CB  . LEU A 1 267 ? -7.961  17.695  30.548  1.00 76.51  ? 267 LEU A CB  1 
ATOM   1962  C CG  . LEU A 1 267 ? -9.031  17.226  29.552  1.00 75.84  ? 267 LEU A CG  1 
ATOM   1963  C CD1 . LEU A 1 267 ? -9.256  15.732  29.676  1.00 75.62  ? 267 LEU A CD1 1 
ATOM   1964  C CD2 . LEU A 1 267 ? -10.350 17.990  29.721  1.00 71.45  ? 267 LEU A CD2 1 
ATOM   1965  N N   . GLY A 1 268 ? -7.106  19.173  33.109  1.00 70.45  ? 268 GLY A N   1 
ATOM   1966  C CA  . GLY A 1 268 ? -6.270  19.555  34.237  1.00 73.00  ? 268 GLY A CA  1 
ATOM   1967  C C   . GLY A 1 268 ? -4.836  19.017  34.112  1.00 75.02  ? 268 GLY A C   1 
ATOM   1968  O O   . GLY A 1 268 ? -3.887  19.675  34.530  1.00 78.66  ? 268 GLY A O   1 
ATOM   1969  N N   . ASP A 1 269 ? -4.690  17.829  33.519  1.00 71.14  ? 269 ASP A N   1 
ATOM   1970  C CA  . ASP A 1 269 ? -3.410  17.131  33.499  1.00 71.00  ? 269 ASP A CA  1 
ATOM   1971  C C   . ASP A 1 269 ? -2.612  17.516  32.245  1.00 68.91  ? 269 ASP A C   1 
ATOM   1972  O O   . ASP A 1 269 ? -1.540  16.972  32.012  1.00 66.84  ? 269 ASP A O   1 
ATOM   1973  C CB  . ASP A 1 269 ? -3.617  15.628  33.548  1.00 72.38  ? 269 ASP A CB  1 
ATOM   1974  C CG  . ASP A 1 269 ? -4.367  15.072  32.352  1.00 77.70  ? 269 ASP A CG  1 
ATOM   1975  O OD1 . ASP A 1 269 ? -5.391  15.692  31.976  1.00 85.58  ? 269 ASP A OD1 1 
ATOM   1976  O OD2 . ASP A 1 269 ? -3.892  14.078  31.768  1.00 80.22  ? 269 ASP A OD2 1 
ATOM   1977  N N   . ALA A 1 270 ? -3.160  18.432  31.423  1.00 74.36  ? 270 ALA A N   1 
ATOM   1978  C CA  . ALA A 1 270 ? -2.503  18.836  30.176  1.00 76.99  ? 270 ALA A CA  1 
ATOM   1979  C C   . ALA A 1 270 ? -1.130  19.442  30.473  1.00 77.78  ? 270 ALA A C   1 
ATOM   1980  O O   . ALA A 1 270 ? -0.928  20.052  31.519  1.00 74.19  ? 270 ALA A O   1 
ATOM   1981  C CB  . ALA A 1 270 ? -3.375  19.808  29.417  1.00 74.32  ? 270 ALA A CB  1 
ATOM   1982  N N   . ASP A 1 271 ? -0.191  19.254  29.544  1.00 78.05  ? 271 ASP A N   1 
ATOM   1983  C CA  . ASP A 1 271 ? 1.053   20.005  29.556  1.00 95.43  ? 271 ASP A CA  1 
ATOM   1984  C C   . ASP A 1 271 ? 0.754   21.436  29.106  1.00 103.09 ? 271 ASP A C   1 
ATOM   1985  O O   . ASP A 1 271 ? 0.401   21.662  27.952  1.00 101.70 ? 271 ASP A O   1 
ATOM   1986  C CB  . ASP A 1 271 ? 2.127   19.334  28.701  1.00 96.44  ? 271 ASP A CB  1 
ATOM   1987  C CG  . ASP A 1 271 ? 3.399   20.153  28.471  1.00 96.41  ? 271 ASP A CG  1 
ATOM   1988  O OD1 . ASP A 1 271 ? 3.335   21.399  28.594  1.00 99.12  ? 271 ASP A OD1 1 
ATOM   1989  O OD2 . ASP A 1 271 ? 4.446   19.540  28.201  1.00 88.82  ? 271 ASP A OD2 1 
ATOM   1990  N N   . LEU A 1 272 ? 0.936   22.400  30.027  1.00 105.30 ? 272 LEU A N   1 
ATOM   1991  C CA  . LEU A 1 272 ? 0.415   23.746  29.849  1.00 105.55 ? 272 LEU A CA  1 
ATOM   1992  C C   . LEU A 1 272 ? 1.128   24.438  28.674  1.00 102.77 ? 272 LEU A C   1 
ATOM   1993  O O   . LEU A 1 272 ? 0.478   25.060  27.834  1.00 94.87  ? 272 LEU A O   1 
ATOM   1994  C CB  . LEU A 1 272 ? 0.544   24.536  31.153  1.00 108.03 ? 272 LEU A CB  1 
ATOM   1995  C CG  . LEU A 1 272 ? -0.336  25.791  31.277  1.00 112.54 ? 272 LEU A CG  1 
ATOM   1996  C CD1 . LEU A 1 272 ? 0.293   26.974  30.569  1.00 122.56 ? 272 LEU A CD1 1 
ATOM   1997  C CD2 . LEU A 1 272 ? -1.745  25.555  30.741  1.00 109.49 ? 272 LEU A CD2 1 
ATOM   1998  N N   . GLU A 1 273 ? 2.457   24.283  28.587  1.00 107.54 ? 273 GLU A N   1 
ATOM   1999  C CA  . GLU A 1 273 ? 3.221   24.902  27.505  1.00 114.24 ? 273 GLU A CA  1 
ATOM   2000  C C   . GLU A 1 273 ? 2.644   24.484  26.140  1.00 102.48 ? 273 GLU A C   1 
ATOM   2001  O O   . GLU A 1 273 ? 2.443   25.322  25.281  1.00 97.99  ? 273 GLU A O   1 
ATOM   2002  C CB  . GLU A 1 273 ? 4.722   24.597  27.603  1.00 122.66 ? 273 GLU A CB  1 
ATOM   2003  C CG  . GLU A 1 273 ? 5.598   25.549  26.778  1.00 134.87 ? 273 GLU A CG  1 
ATOM   2004  C CD  . GLU A 1 273 ? 5.582   27.024  27.206  1.00 142.07 ? 273 GLU A CD  1 
ATOM   2005  O OE1 . GLU A 1 273 ? 5.054   27.340  28.303  1.00 141.93 ? 273 GLU A OE1 1 
ATOM   2006  O OE2 . GLU A 1 273 ? 6.063   27.862  26.408  1.00 141.57 ? 273 GLU A OE2 1 
ATOM   2007  N N   . GLN A 1 274 ? 2.416   23.196  25.924  1.00 97.00  ? 274 GLN A N   1 
ATOM   2008  C CA  . GLN A 1 274 ? 1.953   22.766  24.615  1.00 94.84  ? 274 GLN A CA  1 
ATOM   2009  C C   . GLN A 1 274 ? 0.577   23.380  24.340  1.00 82.57  ? 274 GLN A C   1 
ATOM   2010  O O   . GLN A 1 274 ? 0.320   23.842  23.237  1.00 77.19  ? 274 GLN A O   1 
ATOM   2011  C CB  . GLN A 1 274 ? 1.952   21.257  24.494  1.00 103.32 ? 274 GLN A CB  1 
ATOM   2012  C CG  . GLN A 1 274 ? 3.346   20.650  24.432  1.00 109.46 ? 274 GLN A CG  1 
ATOM   2013  C CD  . GLN A 1 274 ? 3.417   19.276  25.057  1.00 123.70 ? 274 GLN A CD  1 
ATOM   2014  O OE1 . GLN A 1 274 ? 4.400   18.919  25.714  1.00 133.70 ? 274 GLN A OE1 1 
ATOM   2015  N NE2 . GLN A 1 274 ? 2.376   18.477  24.846  1.00 121.53 ? 274 GLN A NE2 1 
ATOM   2016  N N   . ALA A 1 275 ? -0.267  23.447  25.380  1.00 77.59  ? 275 ALA A N   1 
ATOM   2017  C CA  . ALA A 1 275 ? -1.623  23.965  25.243  1.00 78.14  ? 275 ALA A CA  1 
ATOM   2018  C C   . ALA A 1 275 ? -1.591  25.421  24.770  1.00 79.61  ? 275 ALA A C   1 
ATOM   2019  O O   . ALA A 1 275 ? -2.317  25.780  23.854  1.00 77.75  ? 275 ALA A O   1 
ATOM   2020  C CB  . ALA A 1 275 ? -2.384  23.822  26.551  1.00 73.64  ? 275 ALA A CB  1 
ATOM   2021  N N   . VAL A 1 276 ? -0.752  26.254  25.409  1.00 84.44  ? 276 VAL A N   1 
ATOM   2022  C CA  . VAL A 1 276 ? -0.699  27.679  25.078  1.00 92.61  ? 276 VAL A CA  1 
ATOM   2023  C C   . VAL A 1 276 ? -0.123  27.845  23.661  1.00 77.65  ? 276 VAL A C   1 
ATOM   2024  O O   . VAL A 1 276 ? -0.730  28.516  22.826  1.00 72.49  ? 276 VAL A O   1 
ATOM   2025  C CB  . VAL A 1 276 ? 0.076   28.534  26.115  1.00 96.11  ? 276 VAL A CB  1 
ATOM   2026  C CG1 . VAL A 1 276 ? -0.654  28.590  27.455  1.00 99.72  ? 276 VAL A CG1 1 
ATOM   2027  C CG2 . VAL A 1 276 ? 1.515   28.068  26.308  1.00 98.22  ? 276 VAL A CG2 1 
ATOM   2028  N N   . SER A 1 277 ? 1.008   27.174  23.384  1.00 67.02  ? 277 SER A N   1 
ATOM   2029  C CA  . SER A 1 277 ? 1.677   27.281  22.087  1.00 74.72  ? 277 SER A CA  1 
ATOM   2030  C C   . SER A 1 277 ? 0.732   26.858  20.959  1.00 75.37  ? 277 SER A C   1 
ATOM   2031  O O   . SER A 1 277 ? 0.621   27.553  19.948  1.00 81.39  ? 277 SER A O   1 
ATOM   2032  C CB  . SER A 1 277 ? 2.962   26.463  22.054  1.00 76.36  ? 277 SER A CB  1 
ATOM   2033  O OG  . SER A 1 277 ? 3.786   26.757  23.173  1.00 87.34  ? 277 SER A OG  1 
ATOM   2034  N N   . ALA A 1 278 ? 0.068   25.700  21.138  1.00 81.76  ? 278 ALA A N   1 
ATOM   2035  C CA  . ALA A 1 278 ? -0.850  25.159  20.134  1.00 76.93  ? 278 ALA A CA  1 
ATOM   2036  C C   . ALA A 1 278 ? -2.032  26.116  19.909  1.00 63.93  ? 278 ALA A C   1 
ATOM   2037  O O   . ALA A 1 278 ? -2.438  26.331  18.786  1.00 59.43  ? 278 ALA A O   1 
ATOM   2038  C CB  . ALA A 1 278 ? -1.328  23.772  20.552  1.00 79.10  ? 278 ALA A CB  1 
ATOM   2039  N N   . ALA A 1 279 ? -2.559  26.691  20.992  1.00 62.17  ? 279 ALA A N   1 
ATOM   2040  C CA  . ALA A 1 279 ? -3.722  27.571  20.917  1.00 70.50  ? 279 ALA A CA  1 
ATOM   2041  C C   . ALA A 1 279 ? -3.396  28.826  20.108  1.00 70.63  ? 279 ALA A C   1 
ATOM   2042  O O   . ALA A 1 279 ? -4.201  29.252  19.271  1.00 64.56  ? 279 ALA A O   1 
ATOM   2043  C CB  . ALA A 1 279 ? -4.193  27.925  22.310  1.00 73.17  ? 279 ALA A CB  1 
ATOM   2044  N N   . VAL A 1 280 ? -2.213  29.417  20.363  1.00 72.24  ? 280 VAL A N   1 
ATOM   2045  C CA  . VAL A 1 280 ? -1.831  30.659  19.705  1.00 82.76  ? 280 VAL A CA  1 
ATOM   2046  C C   . VAL A 1 280 ? -1.566  30.371  18.221  1.00 77.48  ? 280 VAL A C   1 
ATOM   2047  O O   . VAL A 1 280 ? -2.069  31.089  17.354  1.00 65.25  ? 280 VAL A O   1 
ATOM   2048  C CB  . VAL A 1 280 ? -0.630  31.361  20.385  1.00 83.34  ? 280 VAL A CB  1 
ATOM   2049  C CG1 . VAL A 1 280 ? -0.877  31.571  21.881  1.00 78.91  ? 280 VAL A CG1 1 
ATOM   2050  C CG2 . VAL A 1 280 ? 0.688   30.631  20.156  1.00 84.62  ? 280 VAL A CG2 1 
ATOM   2051  N N   . PHE A 1 281 ? -0.856  29.257  17.944  1.00 75.54  ? 281 PHE A N   1 
ATOM   2052  C CA  . PHE A 1 281 ? -0.479  28.891  16.575  1.00 86.24  ? 281 PHE A CA  1 
ATOM   2053  C C   . PHE A 1 281 ? -1.742  28.627  15.735  1.00 75.70  ? 281 PHE A C   1 
ATOM   2054  O O   . PHE A 1 281 ? -1.826  29.053  14.603  1.00 73.60  ? 281 PHE A O   1 
ATOM   2055  C CB  . PHE A 1 281 ? 0.445   27.670  16.567  1.00 89.56  ? 281 PHE A CB  1 
ATOM   2056  C CG  . PHE A 1 281 ? 1.519   27.698  15.484  1.00 105.80 ? 281 PHE A CG  1 
ATOM   2057  C CD1 . PHE A 1 281 ? 2.720   28.374  15.695  1.00 122.89 ? 281 PHE A CD1 1 
ATOM   2058  C CD2 . PHE A 1 281 ? 1.340   27.033  14.261  1.00 116.52 ? 281 PHE A CD2 1 
ATOM   2059  C CE1 . PHE A 1 281 ? 3.712   28.392  14.713  1.00 128.34 ? 281 PHE A CE1 1 
ATOM   2060  C CE2 . PHE A 1 281 ? 2.330   27.065  13.279  1.00 117.88 ? 281 PHE A CE2 1 
ATOM   2061  C CZ  . PHE A 1 281 ? 3.514   27.738  13.508  1.00 122.10 ? 281 PHE A CZ  1 
ATOM   2062  N N   . GLY A 1 282 ? -2.734  27.955  16.332  1.00 71.88  ? 282 GLY A N   1 
ATOM   2063  C CA  . GLY A 1 282 ? -3.943  27.546  15.622  1.00 75.48  ? 282 GLY A CA  1 
ATOM   2064  C C   . GLY A 1 282 ? -4.825  28.733  15.223  1.00 74.30  ? 282 GLY A C   1 
ATOM   2065  O O   . GLY A 1 282 ? -5.135  28.907  14.040  1.00 73.00  ? 282 GLY A O   1 
ATOM   2066  N N   . LYS A 1 283 ? -5.224  29.540  16.221  1.00 83.87  ? 283 LYS A N   1 
ATOM   2067  C CA  . LYS A 1 283 ? -6.203  30.608  16.022  1.00 85.80  ? 283 LYS A CA  1 
ATOM   2068  C C   . LYS A 1 283 ? -5.614  31.732  15.145  1.00 84.17  ? 283 LYS A C   1 
ATOM   2069  O O   . LYS A 1 283 ? -6.243  32.139  14.165  1.00 74.61  ? 283 LYS A O   1 
ATOM   2070  C CB  . LYS A 1 283 ? -6.700  31.127  17.379  1.00 79.50  ? 283 LYS A CB  1 
ATOM   2071  C CG  . LYS A 1 283 ? -7.563  32.383  17.327  1.00 81.82  ? 283 LYS A CG  1 
ATOM   2072  C CD  . LYS A 1 283 ? -8.580  32.412  16.187  1.00 78.34  ? 283 LYS A CD  1 
ATOM   2073  C CE  . LYS A 1 283 ? -9.633  33.432  16.394  1.00 74.98  ? 283 LYS A CE  1 
ATOM   2074  N NZ  . LYS A 1 283 ? -10.872 33.095  15.679  1.00 76.07  ? 283 LYS A NZ  1 
ATOM   2075  N N   . PHE A 1 284 ? -4.412  32.232  15.503  1.00 90.94  ? 284 PHE A N   1 
ATOM   2076  C CA  . PHE A 1 284 ? -3.929  33.511  14.960  1.00 98.64  ? 284 PHE A CA  1 
ATOM   2077  C C   . PHE A 1 284 ? -3.131  33.272  13.683  1.00 100.09 ? 284 PHE A C   1 
ATOM   2078  O O   . PHE A 1 284 ? -3.266  34.037  12.725  1.00 95.60  ? 284 PHE A O   1 
ATOM   2079  C CB  . PHE A 1 284 ? -3.102  34.300  15.980  1.00 84.63  ? 284 PHE A CB  1 
ATOM   2080  C CG  . PHE A 1 284 ? -3.858  34.599  17.259  1.00 76.13  ? 284 PHE A CG  1 
ATOM   2081  C CD1 . PHE A 1 284 ? -4.813  35.614  17.310  1.00 78.70  ? 284 PHE A CD1 1 
ATOM   2082  C CD2 . PHE A 1 284 ? -3.663  33.818  18.393  1.00 80.57  ? 284 PHE A CD2 1 
ATOM   2083  C CE1 . PHE A 1 284 ? -5.521  35.863  18.481  1.00 81.37  ? 284 PHE A CE1 1 
ATOM   2084  C CE2 . PHE A 1 284 ? -4.383  34.057  19.554  1.00 79.28  ? 284 PHE A CE2 1 
ATOM   2085  C CZ  . PHE A 1 284 ? -5.300  35.087  19.604  1.00 85.14  ? 284 PHE A CZ  1 
ATOM   2086  N N   . LEU A 1 285 ? -2.300  32.210  13.680  1.00 94.93  ? 285 LEU A N   1 
ATOM   2087  C CA  . LEU A 1 285 ? -1.515  31.839  12.501  1.00 100.10 ? 285 LEU A CA  1 
ATOM   2088  C C   . LEU A 1 285 ? -2.258  30.755  11.701  1.00 110.48 ? 285 LEU A C   1 
ATOM   2089  O O   . LEU A 1 285 ? -1.629  29.869  11.109  1.00 99.76  ? 285 LEU A O   1 
ATOM   2090  C CB  . LEU A 1 285 ? -0.128  31.378  12.945  1.00 93.93  ? 285 LEU A CB  1 
ATOM   2091  C CG  . LEU A 1 285 ? 0.572   32.278  13.967  1.00 89.73  ? 285 LEU A CG  1 
ATOM   2092  C CD1 . LEU A 1 285 ? 1.982   31.804  14.267  1.00 84.42  ? 285 LEU A CD1 1 
ATOM   2093  C CD2 . LEU A 1 285 ? 0.584   33.722  13.479  1.00 94.80  ? 285 LEU A CD2 1 
ATOM   2094  N N   . HIS A 1 286 ? -3.604  30.868  11.675  1.00 124.50 ? 286 HIS A N   1 
ATOM   2095  C CA  . HIS A 1 286 ? -4.491  29.939  10.979  1.00 121.62 ? 286 HIS A CA  1 
ATOM   2096  C C   . HIS A 1 286 ? -3.754  28.638  10.635  1.00 111.00 ? 286 HIS A C   1 
ATOM   2097  O O   . HIS A 1 286 ? -4.364  27.832  9.872   1.00 114.62 ? 286 HIS A O   1 
ATOM   2098  C CB  . HIS A 1 286 ? -5.075  30.602  9.732   1.00 135.34 ? 286 HIS A CB  1 
ATOM   2099  C CG  . HIS A 1 286 ? -6.511  30.280  9.503   1.00 148.31 ? 286 HIS A CG  1 
ATOM   2100  N ND1 . HIS A 1 286 ? -6.955  29.014  9.177   1.00 155.05 ? 286 HIS A ND1 1 
ATOM   2101  C CD2 . HIS A 1 286 ? -7.612  31.048  9.591   1.00 145.99 ? 286 HIS A CD2 1 
ATOM   2102  C CE1 . HIS A 1 286 ? -8.276  29.029  9.050   1.00 143.34 ? 286 HIS A CE1 1 
ATOM   2103  N NE2 . HIS A 1 286 ? -8.697  30.256  9.286   1.00 144.53 ? 286 HIS A NE2 1 
ATOM   2104  N N   . ILE A 1 294 ? -10.586 27.217  15.162  1.00 109.32 ? 294 ILE A N   1 
ATOM   2105  C CA  . ILE A 1 294 ? -10.706 27.238  16.657  1.00 103.34 ? 294 ILE A CA  1 
ATOM   2106  C C   . ILE A 1 294 ? -11.230 28.604  17.089  1.00 89.93  ? 294 ILE A C   1 
ATOM   2107  O O   . ILE A 1 294 ? -10.572 29.603  16.885  1.00 95.85  ? 294 ILE A O   1 
ATOM   2108  C CB  . ILE A 1 294 ? -9.357  26.913  17.328  1.00 105.77 ? 294 ILE A CB  1 
ATOM   2109  C CG1 . ILE A 1 294 ? -8.793  25.536  16.867  1.00 120.79 ? 294 ILE A CG1 1 
ATOM   2110  C CG2 . ILE A 1 294 ? -9.469  27.005  18.851  1.00 102.71 ? 294 ILE A CG2 1 
ATOM   2111  C CD1 . ILE A 1 294 ? -9.847  24.447  16.667  1.00 119.16 ? 294 ILE A CD1 1 
ATOM   2112  N N   . ASN A 1 295 ? -12.403 28.615  17.728  1.00 81.54  ? 295 ASN A N   1 
ATOM   2113  C CA  . ASN A 1 295 ? -13.131 29.850  18.016  1.00 86.75  ? 295 ASN A CA  1 
ATOM   2114  C C   . ASN A 1 295 ? -13.281 30.051  19.528  1.00 83.90  ? 295 ASN A C   1 
ATOM   2115  O O   . ASN A 1 295 ? -13.524 31.171  19.990  1.00 85.19  ? 295 ASN A O   1 
ATOM   2116  C CB  . ASN A 1 295 ? -14.512 29.843  17.372  1.00 95.08  ? 295 ASN A CB  1 
ATOM   2117  C CG  . ASN A 1 295 ? -14.464 29.995  15.864  1.00 103.18 ? 295 ASN A CG  1 
ATOM   2118  O OD1 . ASN A 1 295 ? -13.533 29.517  15.210  1.00 92.67  ? 295 ASN A OD1 1 
ATOM   2119  N ND2 . ASN A 1 295 ? -15.473 30.624  15.296  1.00 114.79 ? 295 ASN A ND2 1 
ATOM   2120  N N   . ARG A 1 296 ? -13.208 28.944  20.284  1.00 81.74  ? 296 ARG A N   1 
ATOM   2121  C CA  . ARG A 1 296 ? -13.476 28.954  21.717  1.00 74.65  ? 296 ARG A CA  1 
ATOM   2122  C C   . ARG A 1 296 ? -12.455 28.062  22.423  1.00 73.27  ? 296 ARG A C   1 
ATOM   2123  O O   . ARG A 1 296 ? -12.116 26.972  21.932  1.00 76.82  ? 296 ARG A O   1 
ATOM   2124  C CB  . ARG A 1 296 ? -14.918 28.507  21.955  1.00 76.05  ? 296 ARG A CB  1 
ATOM   2125  C CG  . ARG A 1 296 ? -15.222 27.869  23.303  1.00 84.95  ? 296 ARG A CG  1 
ATOM   2126  C CD  . ARG A 1 296 ? -16.643 27.294  23.305  1.00 88.26  ? 296 ARG A CD  1 
ATOM   2127  N NE  . ARG A 1 296 ? -16.990 26.830  21.957  1.00 85.93  ? 296 ARG A NE  1 
ATOM   2128  C CZ  . ARG A 1 296 ? -17.739 25.793  21.633  1.00 81.73  ? 296 ARG A CZ  1 
ATOM   2129  N NH1 . ARG A 1 296 ? -18.521 25.209  22.527  1.00 81.75  ? 296 ARG A NH1 1 
ATOM   2130  N NH2 . ARG A 1 296 ? -17.754 25.384  20.381  1.00 82.93  ? 296 ARG A NH2 1 
ATOM   2131  N N   . ILE A 1 297 ? -11.968 28.534  23.580  1.00 65.05  ? 297 ILE A N   1 
ATOM   2132  C CA  . ILE A 1 297 ? -11.025 27.776  24.389  1.00 69.24  ? 297 ILE A CA  1 
ATOM   2133  C C   . ILE A 1 297 ? -11.660 27.470  25.752  1.00 77.20  ? 297 ILE A C   1 
ATOM   2134  O O   . ILE A 1 297 ? -12.101 28.377  26.453  1.00 81.74  ? 297 ILE A O   1 
ATOM   2135  C CB  . ILE A 1 297 ? -9.689  28.526  24.540  1.00 63.62  ? 297 ILE A CB  1 
ATOM   2136  C CG1 . ILE A 1 297 ? -9.085  28.876  23.172  1.00 65.97  ? 297 ILE A CG1 1 
ATOM   2137  C CG2 . ILE A 1 297 ? -8.709  27.728  25.414  1.00 64.24  ? 297 ILE A CG2 1 
ATOM   2138  C CD1 . ILE A 1 297 ? -7.613  29.253  23.211  1.00 64.69  ? 297 ILE A CD1 1 
ATOM   2139  N N   . ILE A 1 298 ? -11.668 26.174  26.117  1.00 69.83  ? 298 ILE A N   1 
ATOM   2140  C CA  . ILE A 1 298 ? -12.245 25.708  27.361  1.00 61.79  ? 298 ILE A CA  1 
ATOM   2141  C C   . ILE A 1 298 ? -11.135 25.101  28.221  1.00 65.81  ? 298 ILE A C   1 
ATOM   2142  O O   . ILE A 1 298 ? -10.448 24.156  27.793  1.00 57.38  ? 298 ILE A O   1 
ATOM   2143  C CB  . ILE A 1 298 ? -13.362 24.691  27.084  1.00 68.60  ? 298 ILE A CB  1 
ATOM   2144  C CG1 . ILE A 1 298 ? -14.545 25.330  26.384  1.00 64.99  ? 298 ILE A CG1 1 
ATOM   2145  C CG2 . ILE A 1 298 ? -13.787 23.980  28.371  1.00 78.97  ? 298 ILE A CG2 1 
ATOM   2146  C CD1 . ILE A 1 298 ? -15.310 24.377  25.484  1.00 62.58  ? 298 ILE A CD1 1 
ATOM   2147  N N   . VAL A 1 299 ? -11.001 25.610  29.460  1.00 64.77  ? 299 VAL A N   1 
ATOM   2148  C CA  . VAL A 1 299 ? -9.972  25.126  30.378  1.00 66.19  ? 299 VAL A CA  1 
ATOM   2149  C C   . VAL A 1 299 ? -10.635 24.732  31.701  1.00 70.42  ? 299 VAL A C   1 
ATOM   2150  O O   . VAL A 1 299 ? -11.508 25.446  32.211  1.00 63.06  ? 299 VAL A O   1 
ATOM   2151  C CB  . VAL A 1 299 ? -8.844  26.160  30.614  1.00 64.24  ? 299 VAL A CB  1 
ATOM   2152  C CG1 . VAL A 1 299 ? -7.584  25.508  31.194  1.00 57.43  ? 299 VAL A CG1 1 
ATOM   2153  C CG2 . VAL A 1 299 ? -8.502  26.954  29.344  1.00 61.47  ? 299 VAL A CG2 1 
ATOM   2154  N N   . GLU A 1 300 ? -10.193 23.586  32.250  1.00 79.11  ? 300 GLU A N   1 
ATOM   2155  C CA  . GLU A 1 300 ? -10.558 23.158  33.598  1.00 86.81  ? 300 GLU A CA  1 
ATOM   2156  C C   . GLU A 1 300 ? -10.125 24.219  34.625  1.00 91.03  ? 300 GLU A C   1 
ATOM   2157  O O   . GLU A 1 300 ? -9.069  24.841  34.476  1.00 85.82  ? 300 GLU A O   1 
ATOM   2158  C CB  . GLU A 1 300 ? -9.894  21.817  33.934  1.00 83.50  ? 300 GLU A CB  1 
ATOM   2159  C CG  . GLU A 1 300 ? -10.781 20.607  33.667  1.00 83.76  ? 300 GLU A CG  1 
ATOM   2160  C CD  . GLU A 1 300 ? -10.604 19.483  34.678  1.00 84.11  ? 300 GLU A CD  1 
ATOM   2161  O OE1 . GLU A 1 300 ? -9.602  18.726  34.580  1.00 79.48  ? 300 GLU A OE1 1 
ATOM   2162  O OE2 . GLU A 1 300 ? -11.461 19.383  35.589  1.00 81.89  ? 300 GLU A OE2 1 
ATOM   2163  N N   . ASP A 1 301 ? -10.922 24.355  35.706  1.00 87.18  ? 301 ASP A N   1 
ATOM   2164  C CA  . ASP A 1 301 ? -10.768 25.444  36.668  1.00 80.43  ? 301 ASP A CA  1 
ATOM   2165  C C   . ASP A 1 301 ? -9.332  25.524  37.159  1.00 73.52  ? 301 ASP A C   1 
ATOM   2166  O O   . ASP A 1 301 ? -8.784  26.609  37.272  1.00 84.86  ? 301 ASP A O   1 
ATOM   2167  C CB  . ASP A 1 301 ? -11.694 25.285  37.861  1.00 88.23  ? 301 ASP A CB  1 
ATOM   2168  C CG  . ASP A 1 301 ? -11.830 26.515  38.751  1.00 91.56  ? 301 ASP A CG  1 
ATOM   2169  O OD1 . ASP A 1 301 ? -11.325 27.592  38.354  1.00 104.15 ? 301 ASP A OD1 1 
ATOM   2170  O OD2 . ASP A 1 301 ? -12.430 26.386  39.834  1.00 95.01  ? 301 ASP A OD2 1 
ATOM   2171  N N   . SER A 1 302 ? -8.764  24.375  37.520  1.00 74.36  ? 302 SER A N   1 
ATOM   2172  C CA  . SER A 1 302 ? -7.460  24.340  38.169  1.00 76.59  ? 302 SER A CA  1 
ATOM   2173  C C   . SER A 1 302 ? -6.420  25.065  37.312  1.00 79.70  ? 302 SER A C   1 
ATOM   2174  O O   . SER A 1 302 ? -5.645  25.865  37.828  1.00 98.42  ? 302 SER A O   1 
ATOM   2175  C CB  . SER A 1 302 ? -7.030  22.923  38.470  1.00 77.12  ? 302 SER A CB  1 
ATOM   2176  O OG  . SER A 1 302 ? -7.115  22.106  37.309  1.00 81.36  ? 302 SER A OG  1 
ATOM   2177  N N   . LEU A 1 303 ? -6.453  24.820  35.989  1.00 80.19  ? 303 LEU A N   1 
ATOM   2178  C CA  . LEU A 1 303 ? -5.402  25.284  35.087  1.00 78.14  ? 303 LEU A CA  1 
ATOM   2179  C C   . LEU A 1 303 ? -5.785  26.609  34.407  1.00 65.22  ? 303 LEU A C   1 
ATOM   2180  O O   . LEU A 1 303 ? -4.966  27.183  33.705  1.00 63.81  ? 303 LEU A O   1 
ATOM   2181  C CB  . LEU A 1 303 ? -5.082  24.207  34.049  1.00 85.10  ? 303 LEU A CB  1 
ATOM   2182  C CG  . LEU A 1 303 ? -3.659  23.643  34.097  1.00 86.04  ? 303 LEU A CG  1 
ATOM   2183  C CD1 . LEU A 1 303 ? -3.410  22.642  32.975  1.00 86.14  ? 303 LEU A CD1 1 
ATOM   2184  C CD2 . LEU A 1 303 ? -2.653  24.788  34.030  1.00 94.71  ? 303 LEU A CD2 1 
ATOM   2185  N N   . TYR A 1 304 ? -7.027  27.088  34.620  1.00 63.71  ? 304 TYR A N   1 
ATOM   2186  C CA  . TYR A 1 304 ? -7.587  28.163  33.800  1.00 62.27  ? 304 TYR A CA  1 
ATOM   2187  C C   . TYR A 1 304 ? -6.702  29.411  33.897  1.00 71.42  ? 304 TYR A C   1 
ATOM   2188  O O   . TYR A 1 304 ? -6.269  29.948  32.869  1.00 77.55  ? 304 TYR A O   1 
ATOM   2189  C CB  . TYR A 1 304 ? -9.020  28.451  34.227  1.00 64.26  ? 304 TYR A CB  1 
ATOM   2190  C CG  . TYR A 1 304 ? -9.724  29.560  33.443  1.00 74.27  ? 304 TYR A CG  1 
ATOM   2191  C CD1 . TYR A 1 304 ? -9.481  30.911  33.715  1.00 69.48  ? 304 TYR A CD1 1 
ATOM   2192  C CD2 . TYR A 1 304 ? -10.664 29.259  32.468  1.00 78.97  ? 304 TYR A CD2 1 
ATOM   2193  C CE1 . TYR A 1 304 ? -10.148 31.920  33.036  1.00 77.75  ? 304 TYR A CE1 1 
ATOM   2194  C CE2 . TYR A 1 304 ? -11.342 30.262  31.780  1.00 87.61  ? 304 TYR A CE2 1 
ATOM   2195  C CZ  . TYR A 1 304 ? -11.086 31.597  32.066  1.00 85.19  ? 304 TYR A CZ  1 
ATOM   2196  O OH  . TYR A 1 304 ? -11.750 32.589  31.381  1.00 78.76  ? 304 TYR A OH  1 
ATOM   2197  N N   . ASP A 1 305 ? -6.440  29.865  35.143  1.00 70.82  ? 305 ASP A N   1 
ATOM   2198  C CA  . ASP A 1 305 ? -5.788  31.152  35.385  1.00 72.02  ? 305 ASP A CA  1 
ATOM   2199  C C   . ASP A 1 305 ? -4.373  31.159  34.794  1.00 75.60  ? 305 ASP A C   1 
ATOM   2200  O O   . ASP A 1 305 ? -3.980  32.126  34.153  1.00 81.11  ? 305 ASP A O   1 
ATOM   2201  C CB  . ASP A 1 305 ? -5.793  31.506  36.861  1.00 65.10  ? 305 ASP A CB  1 
ATOM   2202  C CG  . ASP A 1 305 ? -7.171  31.742  37.447  1.00 75.55  ? 305 ASP A CG  1 
ATOM   2203  O OD1 . ASP A 1 305 ? -7.976  32.455  36.793  1.00 73.60  ? 305 ASP A OD1 1 
ATOM   2204  O OD2 . ASP A 1 305 ? -7.450  31.185  38.525  1.00 83.69  ? 305 ASP A OD2 1 
ATOM   2205  N N   . ALA A 1 306 ? -3.610  30.087  35.037  1.00 75.21  ? 306 ALA A N   1 
ATOM   2206  C CA  . ALA A 1 306 ? -2.247  29.987  34.533  1.00 78.42  ? 306 ALA A CA  1 
ATOM   2207  C C   . ALA A 1 306 ? -2.252  30.046  33.002  1.00 95.01  ? 306 ALA A C   1 
ATOM   2208  O O   . ALA A 1 306 ? -1.414  30.718  32.407  1.00 109.18 ? 306 ALA A O   1 
ATOM   2209  C CB  . ALA A 1 306 ? -1.592  28.712  35.038  1.00 77.98  ? 306 ALA A CB  1 
ATOM   2210  N N   . PHE A 1 307 ? -3.202  29.327  32.375  1.00 96.61  ? 307 PHE A N   1 
ATOM   2211  C CA  . PHE A 1 307 ? -3.331  29.320  30.922  1.00 94.89  ? 307 PHE A CA  1 
ATOM   2212  C C   . PHE A 1 307 ? -3.660  30.738  30.428  1.00 74.98  ? 307 PHE A C   1 
ATOM   2213  O O   . PHE A 1 307 ? -3.020  31.237  29.514  1.00 66.59  ? 307 PHE A O   1 
ATOM   2214  C CB  . PHE A 1 307 ? -4.391  28.306  30.460  1.00 92.89  ? 307 PHE A CB  1 
ATOM   2215  C CG  . PHE A 1 307 ? -4.619  28.301  28.949  1.00 85.40  ? 307 PHE A CG  1 
ATOM   2216  C CD1 . PHE A 1 307 ? -5.542  29.173  28.357  1.00 68.85  ? 307 PHE A CD1 1 
ATOM   2217  C CD2 . PHE A 1 307 ? -3.875  27.467  28.115  1.00 88.04  ? 307 PHE A CD2 1 
ATOM   2218  C CE1 . PHE A 1 307 ? -5.732  29.187  26.978  1.00 67.76  ? 307 PHE A CE1 1 
ATOM   2219  C CE2 . PHE A 1 307 ? -4.069  27.491  26.734  1.00 88.00  ? 307 PHE A CE2 1 
ATOM   2220  C CZ  . PHE A 1 307 ? -5.004  28.353  26.174  1.00 75.02  ? 307 PHE A CZ  1 
ATOM   2221  N N   . ALA A 1 308 ? -4.673  31.360  31.033  1.00 72.12  ? 308 ALA A N   1 
ATOM   2222  C CA  . ALA A 1 308 ? -5.133  32.680  30.610  1.00 84.44  ? 308 ALA A CA  1 
ATOM   2223  C C   . ALA A 1 308 ? -3.972  33.691  30.649  1.00 88.21  ? 308 ALA A C   1 
ATOM   2224  O O   . ALA A 1 308 ? -3.825  34.514  29.744  1.00 85.56  ? 308 ALA A O   1 
ATOM   2225  C CB  . ALA A 1 308 ? -6.294  33.128  31.485  1.00 83.16  ? 308 ALA A CB  1 
ATOM   2226  N N   . ALA A 1 309 ? -3.155  33.612  31.704  1.00 92.26  ? 309 ALA A N   1 
ATOM   2227  C CA  . ALA A 1 309 ? -2.014  34.500  31.872  1.00 92.59  ? 309 ALA A CA  1 
ATOM   2228  C C   . ALA A 1 309 ? -1.042  34.332  30.704  1.00 88.89  ? 309 ALA A C   1 
ATOM   2229  O O   . ALA A 1 309 ? -0.674  35.306  30.050  1.00 103.11 ? 309 ALA A O   1 
ATOM   2230  C CB  . ALA A 1 309 ? -1.331  34.222  33.204  1.00 91.88  ? 309 ALA A CB  1 
ATOM   2231  N N   . ARG A 1 310 ? -0.631  33.090  30.457  1.00 87.19  ? 310 ARG A N   1 
ATOM   2232  C CA  . ARG A 1 310 ? 0.418   32.805  29.488  1.00 89.30  ? 310 ARG A CA  1 
ATOM   2233  C C   . ARG A 1 310 ? -0.093  33.092  28.071  1.00 82.10  ? 310 ARG A C   1 
ATOM   2234  O O   . ARG A 1 310 ? 0.660   33.575  27.225  1.00 87.32  ? 310 ARG A O   1 
ATOM   2235  C CB  . ARG A 1 310 ? 0.879   31.355  29.633  1.00 93.35  ? 310 ARG A CB  1 
ATOM   2236  C CG  . ARG A 1 310 ? 2.389   31.181  29.599  1.00 101.32 ? 310 ARG A CG  1 
ATOM   2237  C CD  . ARG A 1 310 ? 2.813   29.927  30.343  1.00 106.68 ? 310 ARG A CD  1 
ATOM   2238  N NE  . ARG A 1 310 ? 2.452   29.996  31.770  1.00 113.65 ? 310 ARG A NE  1 
ATOM   2239  C CZ  . ARG A 1 310 ? 2.619   29.011  32.673  1.00 115.27 ? 310 ARG A CZ  1 
ATOM   2240  N NH1 . ARG A 1 310 ? 3.213   27.874  32.334  1.00 111.02 ? 310 ARG A NH1 1 
ATOM   2241  N NH2 . ARG A 1 310 ? 2.190   29.175  33.911  1.00 112.98 ? 310 ARG A NH2 1 
ATOM   2242  N N   . PHE A 1 311 ? -1.390  32.834  27.839  1.00 71.89  ? 311 PHE A N   1 
ATOM   2243  C CA  . PHE A 1 311 ? -1.987  32.999  26.518  1.00 76.24  ? 311 PHE A CA  1 
ATOM   2244  C C   . PHE A 1 311 ? -1.850  34.454  26.067  1.00 74.99  ? 311 PHE A C   1 
ATOM   2245  O O   . PHE A 1 311 ? -1.328  34.714  24.984  1.00 73.37  ? 311 PHE A O   1 
ATOM   2246  C CB  . PHE A 1 311 ? -3.454  32.554  26.508  1.00 73.79  ? 311 PHE A CB  1 
ATOM   2247  C CG  . PHE A 1 311 ? -4.097  32.584  25.131  1.00 67.77  ? 311 PHE A CG  1 
ATOM   2248  C CD1 . PHE A 1 311 ? -3.651  31.735  24.111  1.00 68.66  ? 311 PHE A CD1 1 
ATOM   2249  C CD2 . PHE A 1 311 ? -5.134  33.465  24.852  1.00 67.31  ? 311 PHE A CD2 1 
ATOM   2250  C CE1 . PHE A 1 311 ? -4.234  31.772  22.853  1.00 64.01  ? 311 PHE A CE1 1 
ATOM   2251  C CE2 . PHE A 1 311 ? -5.729  33.486  23.596  1.00 64.40  ? 311 PHE A CE2 1 
ATOM   2252  C CZ  . PHE A 1 311 ? -5.278  32.641  22.599  1.00 63.84  ? 311 PHE A CZ  1 
ATOM   2253  N N   . VAL A 1 312 ? -2.289  35.398  26.921  1.00 85.07  ? 312 VAL A N   1 
ATOM   2254  C CA  . VAL A 1 312 ? -2.334  36.815  26.546  1.00 86.36  ? 312 VAL A CA  1 
ATOM   2255  C C   . VAL A 1 312 ? -0.890  37.338  26.390  1.00 78.71  ? 312 VAL A C   1 
ATOM   2256  O O   . VAL A 1 312 ? -0.628  38.193  25.549  1.00 78.42  ? 312 VAL A O   1 
ATOM   2257  C CB  . VAL A 1 312 ? -3.152  37.674  27.539  1.00 84.88  ? 312 VAL A CB  1 
ATOM   2258  C CG1 . VAL A 1 312 ? -4.517  37.049  27.836  1.00 90.14  ? 312 VAL A CG1 1 
ATOM   2259  C CG2 . VAL A 1 312 ? -2.394  37.944  28.832  1.00 87.56  ? 312 VAL A CG2 1 
ATOM   2260  N N   . GLU A 1 313 ? 0.042   36.756  27.169  1.00 71.48  ? 313 GLU A N   1 
ATOM   2261  C CA  . GLU A 1 313 ? 1.472   37.012  27.023  1.00 77.73  ? 313 GLU A CA  1 
ATOM   2262  C C   . GLU A 1 313 ? 1.923   36.781  25.570  1.00 85.63  ? 313 GLU A C   1 
ATOM   2263  O O   . GLU A 1 313 ? 2.602   37.634  24.985  1.00 90.22  ? 313 GLU A O   1 
ATOM   2264  C CB  . GLU A 1 313 ? 2.260   36.113  27.977  1.00 93.55  ? 313 GLU A CB  1 
ATOM   2265  C CG  . GLU A 1 313 ? 2.614   36.769  29.302  1.00 104.56 ? 313 GLU A CG  1 
ATOM   2266  C CD  . GLU A 1 313 ? 3.807   36.090  29.925  1.00 122.97 ? 313 GLU A CD  1 
ATOM   2267  O OE1 . GLU A 1 313 ? 3.712   34.864  30.210  1.00 143.80 ? 313 GLU A OE1 1 
ATOM   2268  O OE2 . GLU A 1 313 ? 4.850   36.754  30.048  1.00 125.45 ? 313 GLU A OE2 1 
ATOM   2269  N N   . ARG A 1 314 ? 1.603   35.595  25.012  1.00 92.96  ? 314 ARG A N   1 
ATOM   2270  C CA  . ARG A 1 314 ? 1.992   35.268  23.641  1.00 87.79  ? 314 ARG A CA  1 
ATOM   2271  C C   . ARG A 1 314 ? 1.188   36.113  22.647  1.00 73.96  ? 314 ARG A C   1 
ATOM   2272  O O   . ARG A 1 314 ? 1.734   36.574  21.662  1.00 67.34  ? 314 ARG A O   1 
ATOM   2273  C CB  . ARG A 1 314 ? 1.852   33.774  23.378  1.00 94.41  ? 314 ARG A CB  1 
ATOM   2274  C CG  . ARG A 1 314 ? 3.069   32.992  23.836  1.00 98.48  ? 314 ARG A CG  1 
ATOM   2275  C CD  . ARG A 1 314 ? 2.681   31.682  24.482  1.00 109.54 ? 314 ARG A CD  1 
ATOM   2276  N NE  . ARG A 1 314 ? 3.832   30.802  24.718  1.00 111.55 ? 314 ARG A NE  1 
ATOM   2277  C CZ  . ARG A 1 314 ? 4.499   30.139  23.766  1.00 111.77 ? 314 ARG A CZ  1 
ATOM   2278  N NH1 . ARG A 1 314 ? 5.546   29.397  24.088  1.00 115.37 ? 314 ARG A NH1 1 
ATOM   2279  N NH2 . ARG A 1 314 ? 4.112   30.223  22.500  1.00 110.82 ? 314 ARG A NH2 1 
ATOM   2280  N N   . VAL A 1 315 ? -0.086  36.363  22.959  1.00 70.44  ? 315 VAL A N   1 
ATOM   2281  C CA  . VAL A 1 315 ? -0.952  37.185  22.115  1.00 82.25  ? 315 VAL A CA  1 
ATOM   2282  C C   . VAL A 1 315 ? -0.389  38.620  22.016  1.00 91.46  ? 315 VAL A C   1 
ATOM   2283  O O   . VAL A 1 315 ? -0.425  39.227  20.945  1.00 94.59  ? 315 VAL A O   1 
ATOM   2284  C CB  . VAL A 1 315 ? -2.402  37.187  22.654  1.00 82.91  ? 315 VAL A CB  1 
ATOM   2285  C CG1 . VAL A 1 315 ? -3.247  38.255  21.992  1.00 85.89  ? 315 VAL A CG1 1 
ATOM   2286  C CG2 . VAL A 1 315 ? -3.074  35.822  22.518  1.00 74.00  ? 315 VAL A CG2 1 
ATOM   2287  N N   . LYS A 1 316 ? 0.110   39.157  23.147  1.00 98.14  ? 316 LYS A N   1 
ATOM   2288  C CA  . LYS A 1 316 ? 0.742   40.479  23.175  1.00 94.19  ? 316 LYS A CA  1 
ATOM   2289  C C   . LYS A 1 316 ? 1.918   40.532  22.186  1.00 94.05  ? 316 LYS A C   1 
ATOM   2290  O O   . LYS A 1 316 ? 2.198   41.575  21.625  1.00 102.10 ? 316 LYS A O   1 
ATOM   2291  C CB  . LYS A 1 316 ? 1.279   40.829  24.572  1.00 95.46  ? 316 LYS A CB  1 
ATOM   2292  C CG  . LYS A 1 316 ? 0.246   41.148  25.644  1.00 99.02  ? 316 LYS A CG  1 
ATOM   2293  C CD  . LYS A 1 316 ? 0.781   40.966  27.068  1.00 99.98  ? 316 LYS A CD  1 
ATOM   2294  C CE  . LYS A 1 316 ? -0.290  41.045  28.134  1.00 98.08  ? 316 LYS A CE  1 
ATOM   2295  N NZ  . LYS A 1 316 ? -0.972  42.344  28.164  1.00 90.58  ? 316 LYS A NZ  1 
ATOM   2296  N N   . GLY A 1 317 ? 2.604   39.391  21.993  1.00 96.06  ? 317 GLY A N   1 
ATOM   2297  C CA  . GLY A 1 317 ? 3.867   39.350  21.249  1.00 94.10  ? 317 GLY A CA  1 
ATOM   2298  C C   . GLY A 1 317 ? 3.671   39.288  19.719  1.00 87.91  ? 317 GLY A C   1 
ATOM   2299  O O   . GLY A 1 317 ? 4.621   39.471  18.973  1.00 82.26  ? 317 GLY A O   1 
ATOM   2300  N N   . LEU A 1 318 ? 2.445   38.995  19.264  1.00 90.21  ? 318 LEU A N   1 
ATOM   2301  C CA  . LEU A 1 318 ? 2.168   38.846  17.832  1.00 93.40  ? 318 LEU A CA  1 
ATOM   2302  C C   . LEU A 1 318 ? 2.212   40.219  17.158  1.00 87.46  ? 318 LEU A C   1 
ATOM   2303  O O   . LEU A 1 318 ? 1.640   41.165  17.675  1.00 77.32  ? 318 LEU A O   1 
ATOM   2304  C CB  . LEU A 1 318 ? 0.798   38.188  17.633  1.00 91.47  ? 318 LEU A CB  1 
ATOM   2305  C CG  . LEU A 1 318 ? 0.616   36.792  18.237  1.00 81.11  ? 318 LEU A CG  1 
ATOM   2306  C CD1 . LEU A 1 318 ? -0.865  36.401  18.208  1.00 78.05  ? 318 LEU A CD1 1 
ATOM   2307  C CD2 . LEU A 1 318 ? 1.473   35.762  17.522  1.00 79.04  ? 318 LEU A CD2 1 
ATOM   2308  N N   . ARG A 1 319 ? 2.823   40.294  15.959  1.00 92.38  ? 319 ARG A N   1 
ATOM   2309  C CA  . ARG A 1 319 ? 2.867   41.548  15.215  1.00 95.83  ? 319 ARG A CA  1 
ATOM   2310  C C   . ARG A 1 319 ? 1.695   41.617  14.279  1.00 83.54  ? 319 ARG A C   1 
ATOM   2311  O O   . ARG A 1 319 ? 1.395   40.662  13.578  1.00 80.73  ? 319 ARG A O   1 
ATOM   2312  C CB  . ARG A 1 319 ? 4.111   41.706  14.370  1.00 103.88 ? 319 ARG A CB  1 
ATOM   2313  N N   . VAL A 1 320 ? 1.056   42.760  14.273  1.00 76.60  ? 320 VAL A N   1 
ATOM   2314  C CA  . VAL A 1 320 ? 0.050   43.061  13.296  1.00 79.19  ? 320 VAL A CA  1 
ATOM   2315  C C   . VAL A 1 320 ? 0.668   44.013  12.297  1.00 81.12  ? 320 VAL A C   1 
ATOM   2316  O O   . VAL A 1 320 ? 1.200   45.036  12.682  1.00 81.45  ? 320 VAL A O   1 
ATOM   2317  C CB  . VAL A 1 320 ? -1.190  43.663  13.982  1.00 79.50  ? 320 VAL A CB  1 
ATOM   2318  C CG1 . VAL A 1 320 ? -2.403  43.641  13.065  1.00 84.74  ? 320 VAL A CG1 1 
ATOM   2319  C CG2 . VAL A 1 320 ? -1.504  42.954  15.302  1.00 76.00  ? 320 VAL A CG2 1 
ATOM   2320  N N   . GLY A 1 321 ? 0.685   43.628  11.025  1.00 85.97  ? 321 GLY A N   1 
ATOM   2321  C CA  . GLY A 1 321 ? 1.431   44.395  10.045  1.00 92.51  ? 321 GLY A CA  1 
ATOM   2322  C C   . GLY A 1 321 ? 1.063   44.057  8.605   1.00 99.95  ? 321 GLY A C   1 
ATOM   2323  O O   . GLY A 1 321 ? 0.000   43.502  8.326   1.00 89.45  ? 321 GLY A O   1 
ATOM   2324  N N   . ASP A 1 322 ? 1.950   44.474  7.693   1.00 107.54 ? 322 ASP A N   1 
ATOM   2325  C CA  . ASP A 1 322 ? 1.797   44.235  6.271   1.00 100.79 ? 322 ASP A CA  1 
ATOM   2326  C C   . ASP A 1 322 ? 1.934   42.740  6.011   1.00 82.63  ? 322 ASP A C   1 
ATOM   2327  O O   . ASP A 1 322 ? 2.916   42.120  6.440   1.00 55.95  ? 322 ASP A O   1 
ATOM   2328  C CB  . ASP A 1 322 ? 2.821   45.037  5.475   1.00 102.73 ? 322 ASP A CB  1 
ATOM   2329  C CG  . ASP A 1 322 ? 2.827   44.786  3.976   1.00 100.97 ? 322 ASP A CG  1 
ATOM   2330  O OD1 . ASP A 1 322 ? 2.769   45.765  3.220   1.00 101.04 ? 322 ASP A OD1 1 
ATOM   2331  O OD2 . ASP A 1 322 ? 2.885   43.609  3.582   1.00 104.48 ? 322 ASP A OD2 1 
ATOM   2332  N N   . PRO A 1 323 ? 0.978   42.119  5.277   1.00 83.93  ? 323 PRO A N   1 
ATOM   2333  C CA  . PRO A 1 323 ? 0.990   40.669  5.085   1.00 85.96  ? 323 PRO A CA  1 
ATOM   2334  C C   . PRO A 1 323 ? 2.199   40.132  4.308   1.00 87.70  ? 323 PRO A C   1 
ATOM   2335  O O   . PRO A 1 323 ? 2.561   38.966  4.465   1.00 90.29  ? 323 PRO A O   1 
ATOM   2336  C CB  . PRO A 1 323 ? -0.345  40.409  4.347   1.00 87.35  ? 323 PRO A CB  1 
ATOM   2337  C CG  . PRO A 1 323 ? -0.638  41.720  3.632   1.00 86.43  ? 323 PRO A CG  1 
ATOM   2338  C CD  . PRO A 1 323 ? -0.155  42.780  4.601   1.00 87.74  ? 323 PRO A CD  1 
ATOM   2339  N N   . GLN A 1 324 ? 2.836   40.996  3.495   1.00 78.86  ? 324 GLN A N   1 
ATOM   2340  C CA  . GLN A 1 324 ? 3.951   40.578  2.646   1.00 72.64  ? 324 GLN A CA  1 
ATOM   2341  C C   . GLN A 1 324 ? 5.152   40.158  3.507   1.00 72.42  ? 324 GLN A C   1 
ATOM   2342  O O   . GLN A 1 324 ? 5.989   39.375  3.072   1.00 64.37  ? 324 GLN A O   1 
ATOM   2343  C CB  . GLN A 1 324 ? 4.343   41.694  1.673   1.00 75.43  ? 324 GLN A CB  1 
ATOM   2344  C CG  . GLN A 1 324 ? 3.309   41.963  0.579   1.00 75.31  ? 324 GLN A CG  1 
ATOM   2345  C CD  . GLN A 1 324 ? 3.511   41.102  -0.646  1.00 74.17  ? 324 GLN A CD  1 
ATOM   2346  O OE1 . GLN A 1 324 ? 4.554   40.455  -0.810  1.00 70.81  ? 324 GLN A OE1 1 
ATOM   2347  N NE2 . GLN A 1 324 ? 2.522   41.102  -1.531  1.00 73.09  ? 324 GLN A NE2 1 
ATOM   2348  N N   . ARG A 1 325 ? 5.252   40.711  4.715   1.00 80.70  ? 325 ARG A N   1 
ATOM   2349  C CA  . ARG A 1 325 ? 6.421   40.483  5.553   1.00 82.55  ? 325 ARG A CA  1 
ATOM   2350  C C   . ARG A 1 325 ? 6.343   39.080  6.179   1.00 82.65  ? 325 ARG A C   1 
ATOM   2351  O O   . ARG A 1 325 ? 5.293   38.671  6.671   1.00 70.57  ? 325 ARG A O   1 
ATOM   2352  C CB  . ARG A 1 325 ? 6.518   41.614  6.584   1.00 94.96  ? 325 ARG A CB  1 
ATOM   2353  C CG  . ARG A 1 325 ? 6.972   42.939  5.965   1.00 99.62  ? 325 ARG A CG  1 
ATOM   2354  C CD  . ARG A 1 325 ? 6.822   44.147  6.905   1.00 98.72  ? 325 ARG A CD  1 
ATOM   2355  N NE  . ARG A 1 325 ? 7.583   43.984  8.151   1.00 102.08 ? 325 ARG A NE  1 
ATOM   2356  C CZ  . ARG A 1 325 ? 8.912   43.826  8.234   1.00 92.09  ? 325 ARG A CZ  1 
ATOM   2357  N NH1 . ARG A 1 325 ? 9.660   43.876  7.147   1.00 88.04  ? 325 ARG A NH1 1 
ATOM   2358  N NH2 . ARG A 1 325 ? 9.480   43.629  9.410   1.00 92.78  ? 325 ARG A NH2 1 
ATOM   2359  N N   . ALA A 1 326 ? 7.479   38.359  6.160   1.00 79.49  ? 326 ALA A N   1 
ATOM   2360  C CA  . ALA A 1 326 ? 7.573   37.016  6.737   1.00 75.10  ? 326 ALA A CA  1 
ATOM   2361  C C   . ALA A 1 326 ? 7.330   37.052  8.251   1.00 81.73  ? 326 ALA A C   1 
ATOM   2362  O O   . ALA A 1 326 ? 6.935   36.061  8.839   1.00 82.26  ? 326 ALA A O   1 
ATOM   2363  C CB  . ALA A 1 326 ? 8.923   36.413  6.425   1.00 71.68  ? 326 ALA A CB  1 
ATOM   2364  N N   . ASP A 1 327 ? 7.598   38.193  8.876   1.00 87.10  ? 327 ASP A N   1 
ATOM   2365  C CA  . ASP A 1 327 ? 7.453   38.318  10.315  1.00 85.42  ? 327 ASP A CA  1 
ATOM   2366  C C   . ASP A 1 327 ? 5.974   38.495  10.679  1.00 87.73  ? 327 ASP A C   1 
ATOM   2367  O O   . ASP A 1 327 ? 5.567   38.126  11.773  1.00 96.26  ? 327 ASP A O   1 
ATOM   2368  C CB  . ASP A 1 327 ? 8.314   39.444  10.859  1.00 88.09  ? 327 ASP A CB  1 
ATOM   2369  C CG  . ASP A 1 327 ? 8.108   40.796  10.188  1.00 92.03  ? 327 ASP A CG  1 
ATOM   2370  O OD1 . ASP A 1 327 ? 7.154   41.510  10.566  1.00 85.61  ? 327 ASP A OD1 1 
ATOM   2371  O OD2 . ASP A 1 327 ? 8.865   41.095  9.259   1.00 112.18 ? 327 ASP A OD2 1 
ATOM   2372  N N   . THR A 1 328 ? 5.173   39.064  9.755   1.00 80.35  ? 328 THR A N   1 
ATOM   2373  C CA  . THR A 1 328 ? 3.810   39.492  10.083  1.00 74.76  ? 328 THR A CA  1 
ATOM   2374  C C   . THR A 1 328 ? 2.983   38.271  10.509  1.00 84.13  ? 328 THR A C   1 
ATOM   2375  O O   . THR A 1 328 ? 2.732   37.370  9.709   1.00 86.56  ? 328 THR A O   1 
ATOM   2376  C CB  . THR A 1 328 ? 3.164   40.213  8.898   1.00 73.55  ? 328 THR A CB  1 
ATOM   2377  O OG1 . THR A 1 328 ? 3.828   41.460  8.720   1.00 87.43  ? 328 THR A OG1 1 
ATOM   2378  C CG2 . THR A 1 328 ? 1.693   40.502  9.129   1.00 69.72  ? 328 THR A CG2 1 
ATOM   2379  N N   . ALA A 1 329 ? 2.524   38.287  11.766  1.00 87.95  ? 329 ALA A N   1 
ATOM   2380  C CA  . ALA A 1 329 ? 1.738   37.198  12.326  1.00 80.92  ? 329 ALA A CA  1 
ATOM   2381  C C   . ALA A 1 329 ? 0.262   37.379  11.967  1.00 73.72  ? 329 ALA A C   1 
ATOM   2382  O O   . ALA A 1 329 ? -0.406  36.432  11.577  1.00 80.66  ? 329 ALA A O   1 
ATOM   2383  C CB  . ALA A 1 329 ? 1.943   37.141  13.826  1.00 82.54  ? 329 ALA A CB  1 
ATOM   2384  N N   . VAL A 1 330 ? -0.231  38.608  12.125  1.00 76.22  ? 330 VAL A N   1 
ATOM   2385  C CA  . VAL A 1 330 ? -1.623  38.931  11.867  1.00 73.38  ? 330 VAL A CA  1 
ATOM   2386  C C   . VAL A 1 330 ? -1.672  39.947  10.734  1.00 73.52  ? 330 VAL A C   1 
ATOM   2387  O O   . VAL A 1 330 ? -0.890  40.895  10.714  1.00 73.01  ? 330 VAL A O   1 
ATOM   2388  C CB  . VAL A 1 330 ? -2.318  39.483  13.130  1.00 76.33  ? 330 VAL A CB  1 
ATOM   2389  C CG1 . VAL A 1 330 ? -3.837  39.368  13.040  1.00 77.49  ? 330 VAL A CG1 1 
ATOM   2390  C CG2 . VAL A 1 330 ? -1.802  38.814  14.403  1.00 79.23  ? 330 VAL A CG2 1 
ATOM   2391  N N   . GLY A 1 331 ? -2.622  39.765  9.819   1.00 71.82  ? 331 GLY A N   1 
ATOM   2392  C CA  . GLY A 1 331 ? -2.766  40.649  8.676   1.00 65.31  ? 331 GLY A CA  1 
ATOM   2393  C C   . GLY A 1 331 ? -4.147  41.284  8.639   1.00 67.32  ? 331 GLY A C   1 
ATOM   2394  O O   . GLY A 1 331 ? -4.916  41.187  9.595   1.00 78.80  ? 331 GLY A O   1 
ATOM   2395  N N   . PRO A 1 332 ? -4.510  41.941  7.532   1.00 62.19  ? 332 PRO A N   1 
ATOM   2396  C CA  . PRO A 1 332 ? -5.770  42.668  7.460   1.00 60.65  ? 332 PRO A CA  1 
ATOM   2397  C C   . PRO A 1 332 ? -6.965  41.764  7.254   1.00 66.25  ? 332 PRO A C   1 
ATOM   2398  O O   . PRO A 1 332 ? -6.856  40.737  6.595   1.00 77.04  ? 332 PRO A O   1 
ATOM   2399  C CB  . PRO A 1 332 ? -5.532  43.593  6.250   1.00 65.56  ? 332 PRO A CB  1 
ATOM   2400  C CG  . PRO A 1 332 ? -4.602  42.787  5.348   1.00 61.94  ? 332 PRO A CG  1 
ATOM   2401  C CD  . PRO A 1 332 ? -3.700  42.051  6.313   1.00 61.52  ? 332 PRO A CD  1 
ATOM   2402  N N   . ILE A 1 333 ? -8.117  42.195  7.769   1.00 74.73  ? 333 ILE A N   1 
ATOM   2403  C CA  . ILE A 1 333 ? -9.391  41.568  7.444   1.00 72.91  ? 333 ILE A CA  1 
ATOM   2404  C C   . ILE A 1 333 ? -9.720  41.849  5.978   1.00 73.85  ? 333 ILE A C   1 
ATOM   2405  O O   . ILE A 1 333 ? -9.413  42.916  5.457   1.00 86.45  ? 333 ILE A O   1 
ATOM   2406  C CB  . ILE A 1 333 ? -10.506 42.048  8.404   1.00 74.39  ? 333 ILE A CB  1 
ATOM   2407  C CG1 . ILE A 1 333 ? -10.659 41.101  9.618   1.00 75.65  ? 333 ILE A CG1 1 
ATOM   2408  C CG2 . ILE A 1 333 ? -11.839 42.228  7.670   1.00 72.28  ? 333 ILE A CG2 1 
ATOM   2409  C CD1 . ILE A 1 333 ? -9.365  40.823  10.370  1.00 70.73  ? 333 ILE A CD1 1 
ATOM   2410  N N   . VAL A 1 334 ? -10.362 40.873  5.339   1.00 80.62  ? 334 VAL A N   1 
ATOM   2411  C CA  . VAL A 1 334 ? -10.509 40.835  3.890   1.00 83.76  ? 334 VAL A CA  1 
ATOM   2412  C C   . VAL A 1 334 ? -11.395 41.999  3.417   1.00 87.16  ? 334 VAL A C   1 
ATOM   2413  O O   . VAL A 1 334 ? -11.085 42.634  2.421   1.00 86.73  ? 334 VAL A O   1 
ATOM   2414  C CB  . VAL A 1 334 ? -11.070 39.465  3.422   1.00 83.73  ? 334 VAL A CB  1 
ATOM   2415  C CG1 . VAL A 1 334 ? -12.241 38.988  4.282   1.00 78.44  ? 334 VAL A CG1 1 
ATOM   2416  C CG2 . VAL A 1 334 ? -11.459 39.478  1.942   1.00 85.49  ? 334 VAL A CG2 1 
ATOM   2417  N N   . ASN A 1 335 ? -12.515 42.242  4.118   1.00 94.17  ? 335 ASN A N   1 
ATOM   2418  C CA  . ASN A 1 335 ? -13.568 43.114  3.602   1.00 103.00 ? 335 ASN A CA  1 
ATOM   2419  C C   . ASN A 1 335 ? -14.208 43.902  4.749   1.00 115.89 ? 335 ASN A C   1 
ATOM   2420  O O   . ASN A 1 335 ? -14.061 43.548  5.924   1.00 112.28 ? 335 ASN A O   1 
ATOM   2421  C CB  . ASN A 1 335 ? -14.618 42.323  2.826   1.00 111.74 ? 335 ASN A CB  1 
ATOM   2422  C CG  . ASN A 1 335 ? -15.776 43.187  2.375   1.00 122.31 ? 335 ASN A CG  1 
ATOM   2423  O OD1 . ASN A 1 335 ? -16.768 43.317  3.095   1.00 129.98 ? 335 ASN A OD1 1 
ATOM   2424  N ND2 . ASN A 1 335 ? -15.656 43.811  1.211   1.00 128.56 ? 335 ASN A ND2 1 
ATOM   2425  N N   . ALA A 1 336 ? -14.992 44.935  4.368   1.00 121.28 ? 336 ALA A N   1 
ATOM   2426  C CA  . ALA A 1 336 ? -15.482 45.951  5.289   1.00 105.19 ? 336 ALA A CA  1 
ATOM   2427  C C   . ALA A 1 336 ? -16.550 45.384  6.241   1.00 103.70 ? 336 ALA A C   1 
ATOM   2428  O O   . ALA A 1 336 ? -16.534 45.717  7.421   1.00 97.54  ? 336 ALA A O   1 
ATOM   2429  C CB  . ALA A 1 336 ? -16.007 47.140  4.507   1.00 95.67  ? 336 ALA A CB  1 
ATOM   2430  N N   . ARG A 1 337 ? -17.502 44.557  5.724   1.00 103.11 ? 337 ARG A N   1 
ATOM   2431  C CA  . ARG A 1 337 ? -18.508 43.918  6.594   1.00 113.60 ? 337 ARG A CA  1 
ATOM   2432  C C   . ARG A 1 337 ? -17.801 43.048  7.626   1.00 116.44 ? 337 ARG A C   1 
ATOM   2433  O O   . ARG A 1 337 ? -18.108 43.103  8.816   1.00 125.01 ? 337 ARG A O   1 
ATOM   2434  C CB  . ARG A 1 337 ? -19.527 43.021  5.860   1.00 115.00 ? 337 ARG A CB  1 
ATOM   2435  N N   . GLN A 1 338 ? -16.924 42.178  7.136   1.00 116.89 ? 338 GLN A N   1 
ATOM   2436  C CA  . GLN A 1 338 ? -16.231 41.248  7.993   1.00 123.37 ? 338 GLN A CA  1 
ATOM   2437  C C   . GLN A 1 338 ? -15.627 42.025  9.164   1.00 112.16 ? 338 GLN A C   1 
ATOM   2438  O O   . GLN A 1 338 ? -15.865 41.672  10.323  1.00 94.98  ? 338 GLN A O   1 
ATOM   2439  C CB  . GLN A 1 338 ? -15.219 40.401  7.201   1.00 131.61 ? 338 GLN A CB  1 
ATOM   2440  C CG  . GLN A 1 338 ? -15.808 39.117  6.596   1.00 132.12 ? 338 GLN A CG  1 
ATOM   2441  C CD  . GLN A 1 338 ? -16.706 38.352  7.554   1.00 138.78 ? 338 GLN A CD  1 
ATOM   2442  O OE1 . GLN A 1 338 ? -17.383 37.391  7.178   1.00 128.15 ? 338 GLN A OE1 1 
ATOM   2443  N NE2 . GLN A 1 338 ? -16.738 38.785  8.803   1.00 149.92 ? 338 GLN A NE2 1 
ATOM   2444  N N   . LEU A 1 339 ? -14.978 43.167  8.854   1.00 107.51 ? 339 LEU A N   1 
ATOM   2445  C CA  . LEU A 1 339 ? -14.377 44.000  9.886   1.00 103.22 ? 339 LEU A CA  1 
ATOM   2446  C C   . LEU A 1 339 ? -15.470 44.635  10.751  1.00 106.78 ? 339 LEU A C   1 
ATOM   2447  O O   . LEU A 1 339 ? -15.345 44.651  11.968  1.00 113.65 ? 339 LEU A O   1 
ATOM   2448  C CB  . LEU A 1 339 ? -13.437 45.064  9.322   1.00 90.73  ? 339 LEU A CB  1 
ATOM   2449  C CG  . LEU A 1 339 ? -12.637 45.853  10.371  1.00 84.38  ? 339 LEU A CG  1 
ATOM   2450  C CD1 . LEU A 1 339 ? -12.186 44.972  11.514  1.00 85.42  ? 339 LEU A CD1 1 
ATOM   2451  C CD2 . LEU A 1 339 ? -11.448 46.517  9.767   1.00 84.96  ? 339 LEU A CD2 1 
ATOM   2452  N N   . GLU A 1 340 ? -16.521 45.187  10.129  1.00 105.55 ? 340 GLU A N   1 
ATOM   2453  C CA  . GLU A 1 340 ? -17.558 45.873  10.902  1.00 113.26 ? 340 GLU A CA  1 
ATOM   2454  C C   . GLU A 1 340 ? -18.323 44.852  11.768  1.00 111.39 ? 340 GLU A C   1 
ATOM   2455  O O   . GLU A 1 340 ? -18.694 45.158  12.897  1.00 102.63 ? 340 GLU A O   1 
ATOM   2456  C CB  . GLU A 1 340 ? -18.484 46.701  10.009  1.00 117.00 ? 340 GLU A CB  1 
ATOM   2457  C CG  . GLU A 1 340 ? -19.507 45.869  9.252   1.00 123.06 ? 340 GLU A CG  1 
ATOM   2458  C CD  . GLU A 1 340 ? -20.684 45.395  10.091  1.00 132.59 ? 340 GLU A CD  1 
ATOM   2459  O OE1 . GLU A 1 340 ? -20.883 45.917  11.210  1.00 128.03 ? 340 GLU A OE1 1 
ATOM   2460  O OE2 . GLU A 1 340 ? -21.362 44.459  9.640   1.00 142.75 ? 340 GLU A OE2 1 
ATOM   2461  N N   . GLY A 1 341 ? -18.545 43.638  11.231  1.00 104.98 ? 341 GLY A N   1 
ATOM   2462  C CA  . GLY A 1 341 ? -19.199 42.575  11.985  1.00 98.63  ? 341 GLY A CA  1 
ATOM   2463  C C   . GLY A 1 341 ? -18.321 42.117  13.147  1.00 99.91  ? 341 GLY A C   1 
ATOM   2464  O O   . GLY A 1 341 ? -18.824 41.841  14.238  1.00 91.45  ? 341 GLY A O   1 
ATOM   2465  N N   . LEU A 1 342 ? -16.995 42.055  12.871  1.00 108.84 ? 342 LEU A N   1 
ATOM   2466  C CA  . LEU A 1 342 ? -15.953 41.758  13.859  1.00 114.07 ? 342 LEU A CA  1 
ATOM   2467  C C   . LEU A 1 342 ? -16.006 42.769  15.006  1.00 111.14 ? 342 LEU A C   1 
ATOM   2468  O O   . LEU A 1 342 ? -15.912 42.387  16.165  1.00 108.69 ? 342 LEU A O   1 
ATOM   2469  C CB  . LEU A 1 342 ? -14.564 41.754  13.178  1.00 116.68 ? 342 LEU A CB  1 
ATOM   2470  C CG  . LEU A 1 342 ? -14.045 40.398  12.639  1.00 117.72 ? 342 LEU A CG  1 
ATOM   2471  C CD1 . LEU A 1 342 ? -12.811 39.823  13.423  1.00 116.16 ? 342 LEU A CD1 1 
ATOM   2472  C CD2 . LEU A 1 342 ? -15.162 39.364  12.613  1.00 116.91 ? 342 LEU A CD2 1 
ATOM   2473  N N   . LEU A 1 343 ? -16.146 44.061  14.666  1.00 113.72 ? 343 LEU A N   1 
ATOM   2474  C CA  . LEU A 1 343 ? -16.211 45.124  15.666  1.00 109.01 ? 343 LEU A CA  1 
ATOM   2475  C C   . LEU A 1 343 ? -17.529 45.028  16.437  1.00 102.35 ? 343 LEU A C   1 
ATOM   2476  O O   . LEU A 1 343 ? -17.562 45.279  17.644  1.00 79.91  ? 343 LEU A O   1 
ATOM   2477  C CB  . LEU A 1 343 ? -16.058 46.488  14.996  1.00 109.08 ? 343 LEU A CB  1 
ATOM   2478  C CG  . LEU A 1 343 ? -14.700 46.766  14.342  1.00 101.77 ? 343 LEU A CG  1 
ATOM   2479  C CD1 . LEU A 1 343 ? -14.818 47.907  13.344  1.00 103.24 ? 343 LEU A CD1 1 
ATOM   2480  C CD2 . LEU A 1 343 ? -13.630 47.062  15.380  1.00 93.41  ? 343 LEU A CD2 1 
ATOM   2481  N N   . GLU A 1 344 ? -18.611 44.676  15.721  1.00 100.99 ? 344 GLU A N   1 
ATOM   2482  C CA  . GLU A 1 344 ? -19.932 44.540  16.327  1.00 108.46 ? 344 GLU A CA  1 
ATOM   2483  C C   . GLU A 1 344 ? -19.930 43.372  17.319  1.00 113.66 ? 344 GLU A C   1 
ATOM   2484  O O   . GLU A 1 344 ? -20.490 43.486  18.409  1.00 128.27 ? 344 GLU A O   1 
ATOM   2485  C CB  . GLU A 1 344 ? -21.006 44.385  15.242  1.00 111.91 ? 344 GLU A CB  1 
ATOM   2486  C CG  . GLU A 1 344 ? -22.182 43.499  15.651  1.00 112.45 ? 344 GLU A CG  1 
ATOM   2487  C CD  . GLU A 1 344 ? -23.023 44.009  16.809  1.00 108.96 ? 344 GLU A CD  1 
ATOM   2488  O OE1 . GLU A 1 344 ? -22.806 45.144  17.287  1.00 123.26 ? 344 GLU A OE1 1 
ATOM   2489  O OE2 . GLU A 1 344 ? -23.895 43.250  17.239  1.00 104.14 ? 344 GLU A OE2 1 
ATOM   2490  N N   . LYS A 1 345 ? -19.302 42.252  16.925  1.00 113.19 ? 345 LYS A N   1 
ATOM   2491  C CA  . LYS A 1 345 ? -19.267 41.053  17.750  1.00 117.32 ? 345 LYS A CA  1 
ATOM   2492  C C   . LYS A 1 345 ? -18.546 41.353  19.068  1.00 117.98 ? 345 LYS A C   1 
ATOM   2493  O O   . LYS A 1 345 ? -18.966 40.882  20.123  1.00 132.23 ? 345 LYS A O   1 
ATOM   2494  C CB  . LYS A 1 345 ? -18.593 39.892  17.006  1.00 126.09 ? 345 LYS A CB  1 
ATOM   2495  C CG  . LYS A 1 345 ? -19.332 38.561  17.093  1.00 125.95 ? 345 LYS A CG  1 
ATOM   2496  C CD  . LYS A 1 345 ? -18.836 37.484  16.135  1.00 125.60 ? 345 LYS A CD  1 
ATOM   2497  C CE  . LYS A 1 345 ? -19.612 37.425  14.847  1.00 126.78 ? 345 LYS A CE  1 
ATOM   2498  N NZ  . LYS A 1 345 ? -19.652 36.064  14.320  1.00 129.16 ? 345 LYS A NZ  1 
ATOM   2499  N N   . ILE A 1 346 ? -17.469 42.147  18.995  1.00 111.60 ? 346 ILE A N   1 
ATOM   2500  C CA  . ILE A 1 346 ? -16.744 42.562  20.187  1.00 105.36 ? 346 ILE A CA  1 
ATOM   2501  C C   . ILE A 1 346 ? -17.718 43.304  21.114  1.00 112.13 ? 346 ILE A C   1 
ATOM   2502  O O   . ILE A 1 346 ? -17.806 42.979  22.297  1.00 121.30 ? 346 ILE A O   1 
ATOM   2503  C CB  . ILE A 1 346 ? -15.506 43.412  19.820  1.00 98.22  ? 346 ILE A CB  1 
ATOM   2504  C CG1 . ILE A 1 346 ? -14.595 42.674  18.836  1.00 103.18 ? 346 ILE A CG1 1 
ATOM   2505  C CG2 . ILE A 1 346 ? -14.743 43.849  21.072  1.00 94.56  ? 346 ILE A CG2 1 
ATOM   2506  C CD1 . ILE A 1 346 ? -13.211 43.284  18.680  1.00 104.29 ? 346 ILE A CD1 1 
ATOM   2507  N N   . ARG A 1 347 ? -18.536 44.215  20.529  1.00 100.04 ? 347 ARG A N   1 
ATOM   2508  C CA  . ARG A 1 347 ? -19.432 45.075  21.303  1.00 111.31 ? 347 ARG A CA  1 
ATOM   2509  C C   . ARG A 1 347 ? -20.382 44.219  22.140  1.00 117.13 ? 347 ARG A C   1 
ATOM   2510  O O   . ARG A 1 347 ? -20.605 44.482  23.326  1.00 127.25 ? 347 ARG A O   1 
ATOM   2511  C CB  . ARG A 1 347 ? -20.282 45.990  20.403  1.00 117.42 ? 347 ARG A CB  1 
ATOM   2512  C CG  . ARG A 1 347 ? -20.455 47.409  20.946  1.00 117.28 ? 347 ARG A CG  1 
ATOM   2513  C CD  . ARG A 1 347 ? -21.898 47.947  20.894  1.00 119.93 ? 347 ARG A CD  1 
ATOM   2514  N NE  . ARG A 1 347 ? -22.746 47.301  19.882  1.00 127.47 ? 347 ARG A NE  1 
ATOM   2515  C CZ  . ARG A 1 347 ? -23.924 46.702  20.133  1.00 128.24 ? 347 ARG A CZ  1 
ATOM   2516  N NH1 . ARG A 1 347 ? -24.428 46.692  21.363  1.00 124.11 ? 347 ARG A NH1 1 
ATOM   2517  N NH2 . ARG A 1 347 ? -24.589 46.119  19.153  1.00 127.23 ? 347 ARG A NH2 1 
ATOM   2518  N N   . LEU A 1 348 ? -20.979 43.231  21.502  1.00 120.25 ? 348 LEU A N   1 
ATOM   2519  C CA  . LEU A 1 348 ? -22.058 42.500  22.109  1.00 130.38 ? 348 LEU A CA  1 
ATOM   2520  C C   . LEU A 1 348 ? -21.500 41.518  23.189  1.00 131.92 ? 348 LEU A C   1 
ATOM   2521  O O   . LEU A 1 348 ? -22.114 41.351  24.247  1.00 131.89 ? 348 LEU A O   1 
ATOM   2522  C CB  . LEU A 1 348 ? -22.857 41.846  20.958  1.00 138.73 ? 348 LEU A CB  1 
ATOM   2523  C CG  . LEU A 1 348 ? -24.231 41.253  21.320  1.00 138.33 ? 348 LEU A CG  1 
ATOM   2524  C CD1 . LEU A 1 348 ? -25.365 41.281  20.247  1.00 132.19 ? 348 LEU A CD1 1 
ATOM   2525  C CD2 . LEU A 1 348 ? -23.919 39.885  21.672  1.00 144.82 ? 348 LEU A CD2 1 
ATOM   2526  N N   . ALA A 1 349 ? -20.272 40.995  22.999  1.00 130.33 ? 349 ALA A N   1 
ATOM   2527  C CA  . ALA A 1 349 ? -19.558 40.384  24.127  1.00 121.35 ? 349 ALA A CA  1 
ATOM   2528  C C   . ALA A 1 349 ? -19.381 41.424  25.240  1.00 112.13 ? 349 ALA A C   1 
ATOM   2529  O O   . ALA A 1 349 ? -19.557 41.105  26.403  1.00 100.28 ? 349 ALA A O   1 
ATOM   2530  C CB  . ALA A 1 349 ? -18.225 39.787  23.698  1.00 120.66 ? 349 ALA A CB  1 
ATOM   2531  N N   . ARG A 1 350 ? -19.129 42.690  24.862  1.00 116.84 ? 350 ARG A N   1 
ATOM   2532  C CA  . ARG A 1 350 ? -18.949 43.758  25.848  1.00 117.26 ? 350 ARG A CA  1 
ATOM   2533  C C   . ARG A 1 350 ? -20.220 43.911  26.673  1.00 116.65 ? 350 ARG A C   1 
ATOM   2534  O O   . ARG A 1 350 ? -20.151 43.975  27.901  1.00 88.62  ? 350 ARG A O   1 
ATOM   2535  C CB  . ARG A 1 350 ? -18.658 45.127  25.238  1.00 122.06 ? 350 ARG A CB  1 
ATOM   2536  C CG  . ARG A 1 350 ? -17.514 45.145  24.256  1.00 129.19 ? 350 ARG A CG  1 
ATOM   2537  C CD  . ARG A 1 350 ? -16.179 45.228  24.949  1.00 135.09 ? 350 ARG A CD  1 
ATOM   2538  N NE  . ARG A 1 350 ? -15.102 45.290  23.953  1.00 144.88 ? 350 ARG A NE  1 
ATOM   2539  C CZ  . ARG A 1 350 ? -14.141 46.221  23.885  1.00 132.26 ? 350 ARG A CZ  1 
ATOM   2540  N NH1 . ARG A 1 350 ? -13.892 47.001  24.925  1.00 137.68 ? 350 ARG A NH1 1 
ATOM   2541  N NH2 . ARG A 1 350 ? -13.378 46.310  22.806  1.00 124.64 ? 350 ARG A NH2 1 
ATOM   2542  N N   . GLN A 1 351 ? -21.378 43.980  25.972  1.00 127.84 ? 351 GLN A N   1 
ATOM   2543  C CA  . GLN A 1 351 ? -22.676 44.216  26.606  1.00 120.66 ? 351 GLN A CA  1 
ATOM   2544  C C   . GLN A 1 351 ? -23.152 42.941  27.318  1.00 122.17 ? 351 GLN A C   1 
ATOM   2545  O O   . GLN A 1 351 ? -23.919 43.018  28.274  1.00 126.36 ? 351 GLN A O   1 
ATOM   2546  C CB  . GLN A 1 351 ? -23.743 44.673  25.595  1.00 109.41 ? 351 GLN A CB  1 
ATOM   2547  C CG  . GLN A 1 351 ? -23.262 45.722  24.596  1.00 117.12 ? 351 GLN A CG  1 
ATOM   2548  C CD  . GLN A 1 351 ? -22.473 46.845  25.237  1.00 112.69 ? 351 GLN A CD  1 
ATOM   2549  O OE1 . GLN A 1 351 ? -21.253 46.973  25.050  1.00 99.28  ? 351 GLN A OE1 1 
ATOM   2550  N NE2 . GLN A 1 351 ? -23.169 47.683  25.995  1.00 110.58 ? 351 GLN A NE2 1 
ATOM   2551  N N   . GLU A 1 352 ? -22.699 41.770  26.840  1.00 113.91 ? 352 GLU A N   1 
ATOM   2552  C CA  . GLU A 1 352 ? -23.146 40.501  27.404  1.00 111.81 ? 352 GLU A CA  1 
ATOM   2553  C C   . GLU A 1 352 ? -22.267 40.085  28.606  1.00 106.02 ? 352 GLU A C   1 
ATOM   2554  O O   . GLU A 1 352 ? -22.597 39.136  29.306  1.00 115.51 ? 352 GLU A O   1 
ATOM   2555  C CB  . GLU A 1 352 ? -23.214 39.423  26.326  1.00 111.85 ? 352 GLU A CB  1 
ATOM   2556  C CG  . GLU A 1 352 ? -24.587 39.333  25.671  1.00 104.33 ? 352 GLU A CG  1 
ATOM   2557  C CD  . GLU A 1 352 ? -24.689 38.306  24.552  1.00 99.19  ? 352 GLU A CD  1 
ATOM   2558  O OE1 . GLU A 1 352 ? -24.063 37.233  24.648  1.00 102.27 ? 352 GLU A OE1 1 
ATOM   2559  O OE2 . GLU A 1 352 ? -25.427 38.578  23.589  1.00 99.92  ? 352 GLU A OE2 1 
ATOM   2560  N N   . GLY A 1 353 ? -21.174 40.813  28.858  1.00 86.79  ? 353 GLY A N   1 
ATOM   2561  C CA  . GLY A 1 353 ? -20.523 40.770  30.162  1.00 87.62  ? 353 GLY A CA  1 
ATOM   2562  C C   . GLY A 1 353 ? -19.282 39.872  30.179  1.00 89.18  ? 353 GLY A C   1 
ATOM   2563  O O   . GLY A 1 353 ? -18.801 39.515  31.251  1.00 92.53  ? 353 GLY A O   1 
ATOM   2564  N N   . ALA A 1 354 ? -18.730 39.565  28.995  1.00 89.92  ? 354 ALA A N   1 
ATOM   2565  C CA  . ALA A 1 354 ? -17.441 38.875  28.910  1.00 90.82  ? 354 ALA A CA  1 
ATOM   2566  C C   . ALA A 1 354 ? -16.320 39.801  29.386  1.00 87.55  ? 354 ALA A C   1 
ATOM   2567  O O   . ALA A 1 354 ? -16.310 40.994  29.066  1.00 91.59  ? 354 ALA A O   1 
ATOM   2568  C CB  . ALA A 1 354 ? -17.188 38.402  27.494  1.00 95.40  ? 354 ALA A CB  1 
ATOM   2569  N N   . LYS A 1 355 ? -15.353 39.222  30.105  1.00 77.00  ? 355 LYS A N   1 
ATOM   2570  C CA  . LYS A 1 355 ? -14.227 39.971  30.626  1.00 76.44  ? 355 LYS A CA  1 
ATOM   2571  C C   . LYS A 1 355 ? -13.125 40.058  29.563  1.00 89.19  ? 355 LYS A C   1 
ATOM   2572  O O   . LYS A 1 355 ? -12.501 39.054  29.215  1.00 102.86 ? 355 LYS A O   1 
ATOM   2573  C CB  . LYS A 1 355 ? -13.709 39.285  31.882  1.00 74.83  ? 355 LYS A CB  1 
ATOM   2574  C CG  . LYS A 1 355 ? -12.588 40.000  32.574  1.00 71.38  ? 355 LYS A CG  1 
ATOM   2575  C CD  . LYS A 1 355 ? -11.549 39.051  33.152  1.00 72.66  ? 355 LYS A CD  1 
ATOM   2576  C CE  . LYS A 1 355 ? -10.811 39.647  34.273  1.00 74.15  ? 355 LYS A CE  1 
ATOM   2577  N NZ  . LYS A 1 355 ? -10.564 38.667  35.330  1.00 79.21  ? 355 LYS A NZ  1 
ATOM   2578  N N   . PRO A 1 356 ? -12.829 41.263  29.033  1.00 103.70 ? 356 PRO A N   1 
ATOM   2579  C CA  . PRO A 1 356 ? -11.752 41.415  28.051  1.00 102.64 ? 356 PRO A CA  1 
ATOM   2580  C C   . PRO A 1 356 ? -10.369 41.338  28.709  1.00 100.45 ? 356 PRO A C   1 
ATOM   2581  O O   . PRO A 1 356 ? -9.978  42.232  29.454  1.00 99.99  ? 356 PRO A O   1 
ATOM   2582  C CB  . PRO A 1 356 ? -12.049 42.795  27.435  1.00 105.62 ? 356 PRO A CB  1 
ATOM   2583  C CG  . PRO A 1 356 ? -12.716 43.567  28.578  1.00 103.99 ? 356 PRO A CG  1 
ATOM   2584  C CD  . PRO A 1 356 ? -13.521 42.525  29.337  1.00 102.46 ? 356 PRO A CD  1 
ATOM   2585  N N   . LEU A 1 357 ? -9.647  40.244  28.442  1.00 105.71 ? 357 LEU A N   1 
ATOM   2586  C CA  . LEU A 1 357 ? -8.291  40.069  28.957  1.00 103.90 ? 357 LEU A CA  1 
ATOM   2587  C C   . LEU A 1 357 ? -7.340  41.009  28.214  1.00 98.16  ? 357 LEU A C   1 
ATOM   2588  O O   . LEU A 1 357 ? -6.565  41.727  28.834  1.00 92.48  ? 357 LEU A O   1 
ATOM   2589  C CB  . LEU A 1 357 ? -7.842  38.613  28.819  1.00 112.11 ? 357 LEU A CB  1 
ATOM   2590  C CG  . LEU A 1 357 ? -8.566  37.580  29.696  1.00 119.26 ? 357 LEU A CG  1 
ATOM   2591  C CD1 . LEU A 1 357 ? -8.016  36.183  29.404  1.00 111.60 ? 357 LEU A CD1 1 
ATOM   2592  C CD2 . LEU A 1 357 ? -8.459  37.900  31.193  1.00 119.33 ? 357 LEU A CD2 1 
ATOM   2593  N N   . TYR A 1 358 ? -7.387  40.954  26.878  1.00 96.26  ? 358 TYR A N   1 
ATOM   2594  C CA  . TYR A 1 358 ? -6.529  41.767  26.028  1.00 90.74  ? 358 TYR A CA  1 
ATOM   2595  C C   . TYR A 1 358 ? -7.372  42.336  24.889  1.00 89.28  ? 358 TYR A C   1 
ATOM   2596  O O   . TYR A 1 358 ? -8.134  41.617  24.255  1.00 84.61  ? 358 TYR A O   1 
ATOM   2597  C CB  . TYR A 1 358 ? -5.346  40.936  25.501  1.00 90.71  ? 358 TYR A CB  1 
ATOM   2598  C CG  . TYR A 1 358 ? -4.412  41.670  24.536  1.00 97.73  ? 358 TYR A CG  1 
ATOM   2599  C CD1 . TYR A 1 358 ? -3.067  41.892  24.854  1.00 97.20  ? 358 TYR A CD1 1 
ATOM   2600  C CD2 . TYR A 1 358 ? -4.870  42.135  23.302  1.00 101.39 ? 358 TYR A CD2 1 
ATOM   2601  C CE1 . TYR A 1 358 ? -2.220  42.559  23.977  1.00 94.17  ? 358 TYR A CE1 1 
ATOM   2602  C CE2 . TYR A 1 358 ? -4.035  42.815  22.429  1.00 105.64 ? 358 TYR A CE2 1 
ATOM   2603  C CZ  . TYR A 1 358 ? -2.705  43.022  22.766  1.00 99.46  ? 358 TYR A CZ  1 
ATOM   2604  O OH  . TYR A 1 358 ? -1.879  43.682  21.913  1.00 88.99  ? 358 TYR A OH  1 
ATOM   2605  N N   . GLU A 1 359 ? -7.209  43.636  24.634  1.00 95.17  ? 359 GLU A N   1 
ATOM   2606  C CA  . GLU A 1 359 ? -7.829  44.286  23.490  1.00 101.70 ? 359 GLU A CA  1 
ATOM   2607  C C   . GLU A 1 359 ? -6.749  44.952  22.652  1.00 110.26 ? 359 GLU A C   1 
ATOM   2608  O O   . GLU A 1 359 ? -5.929  45.709  23.172  1.00 119.00 ? 359 GLU A O   1 
ATOM   2609  C CB  . GLU A 1 359 ? -8.836  45.344  23.916  1.00 101.63 ? 359 GLU A CB  1 
ATOM   2610  C CG  . GLU A 1 359 ? -10.219 44.790  24.212  1.00 106.65 ? 359 GLU A CG  1 
ATOM   2611  C CD  . GLU A 1 359 ? -10.859 45.474  25.403  1.00 112.00 ? 359 GLU A CD  1 
ATOM   2612  O OE1 . GLU A 1 359 ? -11.813 46.228  25.209  1.00 122.43 ? 359 GLU A OE1 1 
ATOM   2613  O OE2 . GLU A 1 359 ? -10.361 45.272  26.532  1.00 106.58 ? 359 GLU A OE2 1 
ATOM   2614  N N   . GLY A 1 360 ? -6.768  44.667  21.351  1.00 108.78 ? 360 GLY A N   1 
ATOM   2615  C CA  . GLY A 1 360 ? -5.861  45.297  20.415  1.00 98.42  ? 360 GLY A CA  1 
ATOM   2616  C C   . GLY A 1 360 ? -6.527  46.478  19.714  1.00 89.49  ? 360 GLY A C   1 
ATOM   2617  O O   . GLY A 1 360 ? -7.757  46.571  19.645  1.00 74.51  ? 360 GLY A O   1 
ATOM   2618  N N   . GLY A 1 361 ? -5.703  47.387  19.212  1.00 91.21  ? 361 GLY A N   1 
ATOM   2619  C CA  . GLY A 1 361 ? -6.192  48.505  18.438  1.00 98.02  ? 361 GLY A CA  1 
ATOM   2620  C C   . GLY A 1 361 ? -6.500  48.077  17.012  1.00 101.88 ? 361 GLY A C   1 
ATOM   2621  O O   . GLY A 1 361 ? -5.760  47.294  16.425  1.00 125.39 ? 361 GLY A O   1 
ATOM   2622  N N   . VAL A 1 362 ? -7.596  48.602  16.464  1.00 96.05  ? 362 VAL A N   1 
ATOM   2623  C CA  . VAL A 1 362 ? -7.881  48.468  15.046  1.00 92.85  ? 362 VAL A CA  1 
ATOM   2624  C C   . VAL A 1 362 ? -7.277  49.671  14.319  1.00 88.24  ? 362 VAL A C   1 
ATOM   2625  O O   . VAL A 1 362 ? -7.620  50.802  14.611  1.00 91.98  ? 362 VAL A O   1 
ATOM   2626  C CB  . VAL A 1 362 ? -9.395  48.328  14.761  1.00 82.56  ? 362 VAL A CB  1 
ATOM   2627  C CG1 . VAL A 1 362 ? -10.226 49.354  15.515  1.00 76.93  ? 362 VAL A CG1 1 
ATOM   2628  C CG2 . VAL A 1 362 ? -9.705  48.386  13.269  1.00 80.61  ? 362 VAL A CG2 1 
ATOM   2629  N N   . ASP A 1 363 ? -6.364  49.399  13.379  1.00 95.69  ? 363 ASP A N   1 
ATOM   2630  C CA  . ASP A 1 363 ? -5.776  50.433  12.542  1.00 93.31  ? 363 ASP A CA  1 
ATOM   2631  C C   . ASP A 1 363 ? -6.107  50.131  11.078  1.00 90.23  ? 363 ASP A C   1 
ATOM   2632  O O   . ASP A 1 363 ? -5.444  49.309  10.444  1.00 76.56  ? 363 ASP A O   1 
ATOM   2633  C CB  . ASP A 1 363 ? -4.281  50.545  12.792  1.00 94.45  ? 363 ASP A CB  1 
ATOM   2634  C CG  . ASP A 1 363 ? -3.644  51.871  12.399  1.00 103.45 ? 363 ASP A CG  1 
ATOM   2635  O OD1 . ASP A 1 363 ? -4.272  52.626  11.609  1.00 103.87 ? 363 ASP A OD1 1 
ATOM   2636  O OD2 . ASP A 1 363 ? -2.543  52.156  12.908  1.00 102.51 ? 363 ASP A OD2 1 
ATOM   2637  N N   . GLY A 1 364 ? -7.152  50.795  10.557  1.00 93.48  ? 364 GLY A N   1 
ATOM   2638  C CA  . GLY A 1 364 ? -7.650  50.519  9.216   1.00 91.76  ? 364 GLY A CA  1 
ATOM   2639  C C   . GLY A 1 364 ? -8.217  49.109  9.138   1.00 96.81  ? 364 GLY A C   1 
ATOM   2640  O O   . GLY A 1 364 ? -8.973  48.712  10.011  1.00 106.66 ? 364 GLY A O   1 
ATOM   2641  N N   . GLN A 1 365 ? -7.780  48.330  8.121   1.00 93.26  ? 365 GLN A N   1 
ATOM   2642  C CA  . GLN A 1 365 ? -8.222  46.936  7.962   1.00 82.65  ? 365 GLN A CA  1 
ATOM   2643  C C   . GLN A 1 365 ? -7.584  46.051  9.055   1.00 80.62  ? 365 GLN A C   1 
ATOM   2644  O O   . GLN A 1 365 ? -8.118  44.985  9.369   1.00 76.85  ? 365 GLN A O   1 
ATOM   2645  C CB  . GLN A 1 365 ? -7.825  46.281  6.629   1.00 82.44  ? 365 GLN A CB  1 
ATOM   2646  C CG  . GLN A 1 365 ? -8.869  46.269  5.474   1.00 89.99  ? 365 GLN A CG  1 
ATOM   2647  C CD  . GLN A 1 365 ? -10.324 46.584  5.818   1.00 88.75  ? 365 GLN A CD  1 
ATOM   2648  O OE1 . GLN A 1 365 ? -10.699 46.804  6.955   1.00 94.44  ? 365 GLN A OE1 1 
ATOM   2649  N NE2 . GLN A 1 365 ? -11.168 46.611  4.795   1.00 91.30  ? 365 GLN A NE2 1 
ATOM   2650  N N   . LEU A 1 366 ? -6.396  46.458  9.560   1.00 75.59  ? 366 LEU A N   1 
ATOM   2651  C CA  . LEU A 1 366 ? -5.634  45.649  10.529  1.00 84.08  ? 366 LEU A CA  1 
ATOM   2652  C C   . LEU A 1 366 ? -6.405  45.575  11.860  1.00 90.16  ? 366 LEU A C   1 
ATOM   2653  O O   . LEU A 1 366 ? -6.516  46.574  12.570  1.00 99.98  ? 366 LEU A O   1 
ATOM   2654  C CB  . LEU A 1 366 ? -4.219  46.221  10.766  1.00 85.30  ? 366 LEU A CB  1 
ATOM   2655  C CG  . LEU A 1 366 ? -3.123  45.890  9.729   1.00 83.46  ? 366 LEU A CG  1 
ATOM   2656  C CD1 . LEU A 1 366 ? -1.730  46.138  10.347  1.00 76.79  ? 366 LEU A CD1 1 
ATOM   2657  C CD2 . LEU A 1 366 ? -3.203  44.474  9.179   1.00 82.40  ? 366 LEU A CD2 1 
ATOM   2658  N N   . LEU A 1 367 ? -6.863  44.361  12.228  1.00 83.77  ? 367 LEU A N   1 
ATOM   2659  C CA  . LEU A 1 367 ? -7.514  44.138  13.515  1.00 79.15  ? 367 LEU A CA  1 
ATOM   2660  C C   . LEU A 1 367 ? -6.579  43.321  14.404  1.00 80.25  ? 367 LEU A C   1 
ATOM   2661  O O   . LEU A 1 367 ? -6.252  42.181  14.090  1.00 89.02  ? 367 LEU A O   1 
ATOM   2662  C CB  . LEU A 1 367 ? -8.857  43.440  13.317  1.00 78.62  ? 367 LEU A CB  1 
ATOM   2663  C CG  . LEU A 1 367 ? -9.951  43.744  14.356  1.00 83.92  ? 367 LEU A CG  1 
ATOM   2664  C CD1 . LEU A 1 367 ? -11.144 42.804  14.166  1.00 84.57  ? 367 LEU A CD1 1 
ATOM   2665  C CD2 . LEU A 1 367 ? -9.449  43.661  15.774  1.00 83.63  ? 367 LEU A CD2 1 
ATOM   2666  N N   . ALA A 1 368 ? -6.135  43.930  15.501  1.00 83.13  ? 368 ALA A N   1 
ATOM   2667  C CA  . ALA A 1 368 ? -5.250  43.268  16.440  1.00 88.98  ? 368 ALA A CA  1 
ATOM   2668  C C   . ALA A 1 368 ? -6.038  42.211  17.237  1.00 84.21  ? 368 ALA A C   1 
ATOM   2669  O O   . ALA A 1 368 ? -7.275  42.222  17.256  1.00 70.32  ? 368 ALA A O   1 
ATOM   2670  C CB  . ALA A 1 368 ? -4.597  44.307  17.350  1.00 89.25  ? 368 ALA A CB  1 
ATOM   2671  N N   . PRO A 1 369 ? -5.349  41.259  17.908  1.00 79.87  ? 369 PRO A N   1 
ATOM   2672  C CA  . PRO A 1 369 ? -6.034  40.224  18.689  1.00 81.52  ? 369 PRO A CA  1 
ATOM   2673  C C   . PRO A 1 369 ? -6.917  40.786  19.800  1.00 78.80  ? 369 PRO A C   1 
ATOM   2674  O O   . PRO A 1 369 ? -6.569  41.784  20.425  1.00 74.89  ? 369 PRO A O   1 
ATOM   2675  C CB  . PRO A 1 369 ? -4.862  39.381  19.254  1.00 80.28  ? 369 PRO A CB  1 
ATOM   2676  C CG  . PRO A 1 369 ? -3.694  39.672  18.303  1.00 82.11  ? 369 PRO A CG  1 
ATOM   2677  C CD  . PRO A 1 369 ? -3.886  41.108  17.909  1.00 80.56  ? 369 PRO A CD  1 
ATOM   2678  N N   . HIS A 1 370 ? -8.060  40.117  20.032  1.00 80.07  ? 370 HIS A N   1 
ATOM   2679  C CA  . HIS A 1 370 ? -8.926  40.401  21.168  1.00 82.96  ? 370 HIS A CA  1 
ATOM   2680  C C   . HIS A 1 370 ? -9.225  39.104  21.914  1.00 86.18  ? 370 HIS A C   1 
ATOM   2681  O O   . HIS A 1 370 ? -9.716  38.154  21.328  1.00 95.09  ? 370 HIS A O   1 
ATOM   2682  C CB  . HIS A 1 370 ? -10.225 41.068  20.712  1.00 86.78  ? 370 HIS A CB  1 
ATOM   2683  C CG  . HIS A 1 370 ? -10.048 42.469  20.244  1.00 95.90  ? 370 HIS A CG  1 
ATOM   2684  N ND1 . HIS A 1 370 ? -9.175  42.814  19.231  1.00 97.09  ? 370 HIS A ND1 1 
ATOM   2685  C CD2 . HIS A 1 370 ? -10.625 43.618  20.648  1.00 94.43  ? 370 HIS A CD2 1 
ATOM   2686  C CE1 . HIS A 1 370 ? -9.232  44.119  19.035  1.00 99.18  ? 370 HIS A CE1 1 
ATOM   2687  N NE2 . HIS A 1 370 ? -10.106 44.628  19.883  1.00 101.95 ? 370 HIS A NE2 1 
ATOM   2688  N N   . VAL A 1 371 ? -8.941  39.096  23.218  1.00 94.59  ? 371 VAL A N   1 
ATOM   2689  C CA  . VAL A 1 371 ? -9.160  37.930  24.059  1.00 93.61  ? 371 VAL A CA  1 
ATOM   2690  C C   . VAL A 1 371 ? -10.164 38.299  25.155  1.00 91.17  ? 371 VAL A C   1 
ATOM   2691  O O   . VAL A 1 371 ? -10.007 39.316  25.834  1.00 99.38  ? 371 VAL A O   1 
ATOM   2692  C CB  . VAL A 1 371 ? -7.838  37.414  24.670  1.00 89.70  ? 371 VAL A CB  1 
ATOM   2693  C CG1 . VAL A 1 371 ? -8.018  36.058  25.341  1.00 91.31  ? 371 VAL A CG1 1 
ATOM   2694  C CG2 . VAL A 1 371 ? -6.718  37.348  23.641  1.00 89.99  ? 371 VAL A CG2 1 
ATOM   2695  N N   . PHE A 1 372 ? -11.177 37.440  25.335  1.00 91.35  ? 372 PHE A N   1 
ATOM   2696  C CA  . PHE A 1 372 ? -12.149 37.589  26.409  1.00 87.30  ? 372 PHE A CA  1 
ATOM   2697  C C   . PHE A 1 372 ? -12.055 36.391  27.349  1.00 90.02  ? 372 PHE A C   1 
ATOM   2698  O O   . PHE A 1 372 ? -11.624 35.312  26.945  1.00 89.98  ? 372 PHE A O   1 
ATOM   2699  C CB  . PHE A 1 372 ? -13.561 37.718  25.837  1.00 86.25  ? 372 PHE A CB  1 
ATOM   2700  C CG  . PHE A 1 372 ? -13.906 39.109  25.331  1.00 94.34  ? 372 PHE A CG  1 
ATOM   2701  C CD1 . PHE A 1 372 ? -13.655 39.472  24.006  1.00 90.21  ? 372 PHE A CD1 1 
ATOM   2702  C CD2 . PHE A 1 372 ? -14.486 40.056  26.181  1.00 97.47  ? 372 PHE A CD2 1 
ATOM   2703  C CE1 . PHE A 1 372 ? -13.995 40.741  23.545  1.00 94.63  ? 372 PHE A CE1 1 
ATOM   2704  C CE2 . PHE A 1 372 ? -14.805 41.327  25.717  1.00 98.11  ? 372 PHE A CE2 1 
ATOM   2705  C CZ  . PHE A 1 372 ? -14.559 41.668  24.406  1.00 94.32  ? 372 PHE A CZ  1 
ATOM   2706  N N   . GLY A 1 373 ? -12.498 36.595  28.601  1.00 93.82  ? 373 GLY A N   1 
ATOM   2707  C CA  . GLY A 1 373 ? -12.507 35.552  29.617  1.00 83.92  ? 373 GLY A CA  1 
ATOM   2708  C C   . GLY A 1 373 ? -13.896 35.405  30.240  1.00 84.48  ? 373 GLY A C   1 
ATOM   2709  O O   . GLY A 1 373 ? -14.790 36.239  30.004  1.00 83.50  ? 373 GLY A O   1 
ATOM   2710  N N   . GLU A 1 374 ? -14.071 34.319  31.007  1.00 78.83  ? 374 GLU A N   1 
ATOM   2711  C CA  . GLU A 1 374 ? -15.306 34.061  31.747  1.00 83.51  ? 374 GLU A CA  1 
ATOM   2712  C C   . GLU A 1 374 ? -16.510 34.065  30.792  1.00 85.76  ? 374 GLU A C   1 
ATOM   2713  O O   . GLU A 1 374 ? -17.603 34.505  31.158  1.00 90.45  ? 374 GLU A O   1 
ATOM   2714  C CB  . GLU A 1 374 ? -15.510 35.086  32.867  1.00 84.35  ? 374 GLU A CB  1 
ATOM   2715  C CG  . GLU A 1 374 ? -14.244 35.401  33.665  1.00 88.06  ? 374 GLU A CG  1 
ATOM   2716  C CD  . GLU A 1 374 ? -13.559 34.210  34.324  1.00 89.65  ? 374 GLU A CD  1 
ATOM   2717  O OE1 . GLU A 1 374 ? -14.256 33.219  34.717  1.00 82.80  ? 374 GLU A OE1 1 
ATOM   2718  O OE2 . GLU A 1 374 ? -12.318 34.294  34.488  1.00 77.28  ? 374 GLU A OE2 1 
ATOM   2719  N N   . VAL A 1 375 ? -16.313 33.518  29.591  1.00 88.50  ? 375 VAL A N   1 
ATOM   2720  C CA  . VAL A 1 375 ? -17.379 33.410  28.611  1.00 77.43  ? 375 VAL A CA  1 
ATOM   2721  C C   . VAL A 1 375 ? -18.349 32.297  29.051  1.00 75.61  ? 375 VAL A C   1 
ATOM   2722  O O   . VAL A 1 375 ? -17.951 31.349  29.732  1.00 71.28  ? 375 VAL A O   1 
ATOM   2723  C CB  . VAL A 1 375 ? -16.776 33.141  27.214  1.00 72.51  ? 375 VAL A CB  1 
ATOM   2724  C CG1 . VAL A 1 375 ? -17.841 32.810  26.185  1.00 72.56  ? 375 VAL A CG1 1 
ATOM   2725  C CG2 . VAL A 1 375 ? -15.910 34.299  26.733  1.00 68.14  ? 375 VAL A CG2 1 
ATOM   2726  N N   . THR A 1 376 ? -19.622 32.434  28.664  1.00 78.92  ? 376 THR A N   1 
ATOM   2727  C CA  . THR A 1 376 ? -20.635 31.415  28.937  1.00 94.38  ? 376 THR A CA  1 
ATOM   2728  C C   . THR A 1 376 ? -21.191 30.893  27.614  1.00 104.57 ? 376 THR A C   1 
ATOM   2729  O O   . THR A 1 376 ? -21.119 31.573  26.588  1.00 108.10 ? 376 THR A O   1 
ATOM   2730  C CB  . THR A 1 376 ? -21.752 31.989  29.822  1.00 96.44  ? 376 THR A CB  1 
ATOM   2731  O OG1 . THR A 1 376 ? -22.729 32.579  28.947  1.00 85.14  ? 376 THR A OG1 1 
ATOM   2732  C CG2 . THR A 1 376 ? -21.226 32.994  30.836  1.00 93.69  ? 376 THR A CG2 1 
ATOM   2733  N N   . ALA A 1 377 ? -21.800 29.699  27.666  1.00 101.31 ? 377 ALA A N   1 
ATOM   2734  C CA  . ALA A 1 377 ? -22.299 29.036  26.471  1.00 106.55 ? 377 ALA A CA  1 
ATOM   2735  C C   . ALA A 1 377 ? -23.335 29.918  25.764  1.00 109.82 ? 377 ALA A C   1 
ATOM   2736  O O   . ALA A 1 377 ? -23.463 29.878  24.539  1.00 101.95 ? 377 ALA A O   1 
ATOM   2737  C CB  . ALA A 1 377 ? -22.876 27.689  26.836  1.00 107.40 ? 377 ALA A CB  1 
ATOM   2738  N N   . THR A 1 378 ? -24.059 30.731  26.543  1.00 121.03 ? 378 THR A N   1 
ATOM   2739  C CA  . THR A 1 378 ? -25.218 31.439  26.020  1.00 115.27 ? 378 THR A CA  1 
ATOM   2740  C C   . THR A 1 378 ? -24.805 32.776  25.401  1.00 114.11 ? 378 THR A C   1 
ATOM   2741  O O   . THR A 1 378 ? -25.661 33.542  24.980  1.00 106.53 ? 378 THR A O   1 
ATOM   2742  C CB  . THR A 1 378 ? -26.261 31.645  27.114  1.00 109.57 ? 378 THR A CB  1 
ATOM   2743  O OG1 . THR A 1 378 ? -27.242 32.415  26.427  1.00 114.95 ? 378 THR A OG1 1 
ATOM   2744  C CG2 . THR A 1 378 ? -25.724 32.381  28.334  1.00 102.94 ? 378 THR A CG2 1 
ATOM   2745  N N   . MET A 1 379 ? -23.512 33.065  25.359  1.00 113.79 ? 379 MET A N   1 
ATOM   2746  C CA  . MET A 1 379 ? -23.056 34.297  24.745  1.00 106.54 ? 379 MET A CA  1 
ATOM   2747  C C   . MET A 1 379 ? -22.849 34.059  23.253  1.00 117.10 ? 379 MET A C   1 
ATOM   2748  O O   . MET A 1 379 ? -22.506 32.952  22.843  1.00 145.17 ? 379 MET A O   1 
ATOM   2749  C CB  . MET A 1 379 ? -21.785 34.790  25.421  1.00 94.96  ? 379 MET A CB  1 
ATOM   2750  C CG  . MET A 1 379 ? -21.965 35.028  26.902  1.00 93.33  ? 379 MET A CG  1 
ATOM   2751  S SD  . MET A 1 379 ? -20.490 35.644  27.729  1.00 98.28  ? 379 MET A SD  1 
ATOM   2752  C CE  . MET A 1 379 ? -19.610 36.346  26.329  1.00 106.91 ? 379 MET A CE  1 
ATOM   2753  N N   . GLU A 1 380 ? -23.134 35.082  22.441  1.00 114.03 ? 380 GLU A N   1 
ATOM   2754  C CA  . GLU A 1 380 ? -23.102 34.929  20.991  1.00 125.35 ? 380 GLU A CA  1 
ATOM   2755  C C   . GLU A 1 380 ? -21.668 34.619  20.523  1.00 134.03 ? 380 GLU A C   1 
ATOM   2756  O O   . GLU A 1 380 ? -21.479 33.923  19.530  1.00 132.63 ? 380 GLU A O   1 
ATOM   2757  C CB  . GLU A 1 380 ? -23.673 36.171  20.308  1.00 125.67 ? 380 GLU A CB  1 
ATOM   2758  C CG  . GLU A 1 380 ? -23.766 36.062  18.782  1.00 132.29 ? 380 GLU A CG  1 
ATOM   2759  C CD  . GLU A 1 380 ? -22.682 36.798  17.988  1.00 134.58 ? 380 GLU A CD  1 
ATOM   2760  O OE1 . GLU A 1 380 ? -21.873 37.531  18.607  1.00 140.22 ? 380 GLU A OE1 1 
ATOM   2761  O OE2 . GLU A 1 380 ? -22.651 36.631  16.738  1.00 125.55 ? 380 GLU A OE2 1 
ATOM   2762  N N   . ILE A 1 381 ? -20.666 35.127  21.258  1.00 132.21 ? 381 ILE A N   1 
ATOM   2763  C CA  . ILE A 1 381 ? -19.264 34.952  20.882  1.00 131.10 ? 381 ILE A CA  1 
ATOM   2764  C C   . ILE A 1 381 ? -18.906 33.455  20.846  1.00 134.69 ? 381 ILE A C   1 
ATOM   2765  O O   . ILE A 1 381 ? -18.179 33.020  19.962  1.00 132.45 ? 381 ILE A O   1 
ATOM   2766  C CB  . ILE A 1 381 ? -18.331 35.730  21.831  1.00 127.58 ? 381 ILE A CB  1 
ATOM   2767  C CG1 . ILE A 1 381 ? -16.873 35.646  21.369  1.00 127.87 ? 381 ILE A CG1 1 
ATOM   2768  C CG2 . ILE A 1 381 ? -18.491 35.261  23.279  1.00 123.04 ? 381 ILE A CG2 1 
ATOM   2769  C CD1 . ILE A 1 381 ? -15.883 36.306  22.314  1.00 124.91 ? 381 ILE A CD1 1 
ATOM   2770  N N   . ALA A 1 382 ? -19.366 32.696  21.855  1.00 136.80 ? 382 ALA A N   1 
ATOM   2771  C CA  . ALA A 1 382 ? -19.072 31.268  21.953  1.00 124.14 ? 382 ALA A CA  1 
ATOM   2772  C C   . ALA A 1 382 ? -19.851 30.503  20.905  1.00 122.61 ? 382 ALA A C   1 
ATOM   2773  O O   . ALA A 1 382 ? -19.398 29.500  20.388  1.00 131.80 ? 382 ALA A O   1 
ATOM   2774  C CB  . ALA A 1 382 ? -19.424 30.762  23.317  1.00 118.21 ? 382 ALA A CB  1 
ATOM   2775  N N   . ARG A 1 383 ? -21.060 30.943  20.673  1.00 115.89 ? 383 ARG A N   1 
ATOM   2776  C CA  . ARG A 1 383 ? -22.093 30.069  20.187  1.00 116.62 ? 383 ARG A CA  1 
ATOM   2777  C C   . ARG A 1 383 ? -22.188 30.180  18.668  1.00 112.75 ? 383 ARG A C   1 
ATOM   2778  O O   . ARG A 1 383 ? -22.677 29.278  18.012  1.00 116.56 ? 383 ARG A O   1 
ATOM   2779  C CB  . ARG A 1 383 ? -23.354 30.477  20.928  1.00 116.05 ? 383 ARG A CB  1 
ATOM   2780  N N   . ASP A 1 384 ? -21.623 31.253  18.133  1.00 116.05 ? 384 ASP A N   1 
ATOM   2781  C CA  . ASP A 1 384 ? -21.894 31.707  16.783  1.00 119.81 ? 384 ASP A CA  1 
ATOM   2782  C C   . ASP A 1 384 ? -20.523 31.919  16.122  1.00 121.19 ? 384 ASP A C   1 
ATOM   2783  O O   . ASP A 1 384 ? -19.582 32.311  16.800  1.00 131.03 ? 384 ASP A O   1 
ATOM   2784  C CB  . ASP A 1 384 ? -22.790 32.952  16.862  1.00 129.16 ? 384 ASP A CB  1 
ATOM   2785  N N   . GLU A 1 385 ? -20.383 31.565  14.837  1.00 117.96 ? 385 GLU A N   1 
ATOM   2786  C CA  . GLU A 1 385 ? -19.054 31.400  14.244  1.00 125.56 ? 385 GLU A CA  1 
ATOM   2787  C C   . GLU A 1 385 ? -18.346 32.763  14.094  1.00 123.42 ? 385 GLU A C   1 
ATOM   2788  O O   . GLU A 1 385 ? -18.979 33.783  13.832  1.00 121.11 ? 385 GLU A O   1 
ATOM   2789  C CB  . GLU A 1 385 ? -19.125 30.656  12.915  1.00 136.24 ? 385 GLU A CB  1 
ATOM   2790  C CG  . GLU A 1 385 ? -20.024 31.331  11.890  1.00 140.47 ? 385 GLU A CG  1 
ATOM   2791  C CD  . GLU A 1 385 ? -21.081 30.401  11.366  1.00 140.45 ? 385 GLU A CD  1 
ATOM   2792  O OE1 . GLU A 1 385 ? -21.079 30.129  10.157  1.00 132.50 ? 385 GLU A OE1 1 
ATOM   2793  O OE2 . GLU A 1 385 ? -21.891 29.923  12.186  1.00 140.65 ? 385 GLU A OE2 1 
ATOM   2794  N N   . ILE A 1 386 ? -17.010 32.728  14.231  1.00 122.07 ? 386 ILE A N   1 
ATOM   2795  C CA  . ILE A 1 386 ? -16.153 33.911  14.208  1.00 118.07 ? 386 ILE A CA  1 
ATOM   2796  C C   . ILE A 1 386 ? -15.205 33.799  13.012  1.00 112.33 ? 386 ILE A C   1 
ATOM   2797  O O   . ILE A 1 386 ? -14.570 32.758  12.819  1.00 99.22  ? 386 ILE A O   1 
ATOM   2798  C CB  . ILE A 1 386 ? -15.358 34.042  15.529  1.00 112.75 ? 386 ILE A CB  1 
ATOM   2799  C CG1 . ILE A 1 386 ? -16.270 34.408  16.717  1.00 111.43 ? 386 ILE A CG1 1 
ATOM   2800  C CG2 . ILE A 1 386 ? -14.199 35.035  15.368  1.00 109.42 ? 386 ILE A CG2 1 
ATOM   2801  C CD1 . ILE A 1 386 ? -15.576 34.383  18.072  1.00 113.32 ? 386 ILE A CD1 1 
ATOM   2802  N N   . PHE A 1 387 ? -15.055 34.900  12.257  1.00 108.69 ? 387 PHE A N   1 
ATOM   2803  C CA  . PHE A 1 387 ? -14.183 34.916  11.082  1.00 114.81 ? 387 PHE A CA  1 
ATOM   2804  C C   . PHE A 1 387 ? -13.082 35.957  11.251  1.00 98.77  ? 387 PHE A C   1 
ATOM   2805  O O   . PHE A 1 387 ? -12.894 36.803  10.374  1.00 84.24  ? 387 PHE A O   1 
ATOM   2806  C CB  . PHE A 1 387 ? -14.978 35.238  9.819   1.00 125.16 ? 387 PHE A CB  1 
ATOM   2807  C CG  . PHE A 1 387 ? -16.111 34.278  9.534   1.00 139.85 ? 387 PHE A CG  1 
ATOM   2808  C CD1 . PHE A 1 387 ? -15.887 33.112  8.808   1.00 144.80 ? 387 PHE A CD1 1 
ATOM   2809  C CD2 . PHE A 1 387 ? -17.395 34.528  10.011  1.00 149.11 ? 387 PHE A CD2 1 
ATOM   2810  C CE1 . PHE A 1 387 ? -16.921 32.231  8.552   1.00 154.69 ? 387 PHE A CE1 1 
ATOM   2811  C CE2 . PHE A 1 387 ? -18.427 33.644  9.747   1.00 161.37 ? 387 PHE A CE2 1 
ATOM   2812  C CZ  . PHE A 1 387 ? -18.187 32.495  9.022   1.00 164.50 ? 387 PHE A CZ  1 
ATOM   2813  N N   . GLY A 1 388 ? -12.348 35.878  12.367  1.00 87.80  ? 388 GLY A N   1 
ATOM   2814  C CA  . GLY A 1 388 ? -11.305 36.852  12.660  1.00 92.38  ? 388 GLY A CA  1 
ATOM   2815  C C   . GLY A 1 388 ? -10.559 36.516  13.950  1.00 93.74  ? 388 GLY A C   1 
ATOM   2816  O O   . GLY A 1 388 ? -10.825 35.490  14.578  1.00 81.08  ? 388 GLY A O   1 
ATOM   2817  N N   . PRO A 1 389 ? -9.615  37.394  14.395  1.00 91.33  ? 389 PRO A N   1 
ATOM   2818  C CA  . PRO A 1 389 ? -8.745  37.091  15.543  1.00 86.59  ? 389 PRO A CA  1 
ATOM   2819  C C   . PRO A 1 389 ? -9.375  37.446  16.900  1.00 90.68  ? 389 PRO A C   1 
ATOM   2820  O O   . PRO A 1 389 ? -8.777  38.161  17.701  1.00 92.84  ? 389 PRO A O   1 
ATOM   2821  C CB  . PRO A 1 389 ? -7.495  37.935  15.223  1.00 76.54  ? 389 PRO A CB  1 
ATOM   2822  C CG  . PRO A 1 389 ? -8.052  39.161  14.494  1.00 76.71  ? 389 PRO A CG  1 
ATOM   2823  C CD  . PRO A 1 389 ? -9.339  38.705  13.800  1.00 78.04  ? 389 PRO A CD  1 
ATOM   2824  N N   . LEU A 1 390 ? -10.584 36.906  17.141  1.00 91.35  ? 390 LEU A N   1 
ATOM   2825  C CA  . LEU A 1 390 ? -11.317 37.099  18.386  1.00 87.40  ? 390 LEU A CA  1 
ATOM   2826  C C   . LEU A 1 390 ? -11.603 35.733  19.023  1.00 83.35  ? 390 LEU A C   1 
ATOM   2827  O O   . LEU A 1 390 ? -12.187 34.860  18.384  1.00 86.91  ? 390 LEU A O   1 
ATOM   2828  C CB  . LEU A 1 390 ? -12.612 37.855  18.072  1.00 84.89  ? 390 LEU A CB  1 
ATOM   2829  C CG  . LEU A 1 390 ? -13.663 37.899  19.188  1.00 83.34  ? 390 LEU A CG  1 
ATOM   2830  C CD1 . LEU A 1 390 ? -13.181 38.763  20.373  1.00 87.51  ? 390 LEU A CD1 1 
ATOM   2831  C CD2 . LEU A 1 390 ? -15.005 38.404  18.642  1.00 79.96  ? 390 LEU A CD2 1 
ATOM   2832  N N   . VAL A 1 391 ? -11.218 35.571  20.298  1.00 83.08  ? 391 VAL A N   1 
ATOM   2833  C CA  . VAL A 1 391 ? -11.354 34.291  20.986  1.00 83.74  ? 391 VAL A CA  1 
ATOM   2834  C C   . VAL A 1 391 ? -11.905 34.519  22.404  1.00 82.19  ? 391 VAL A C   1 
ATOM   2835  O O   . VAL A 1 391 ? -11.643 35.547  23.029  1.00 76.04  ? 391 VAL A O   1 
ATOM   2836  C CB  . VAL A 1 391 ? -10.003 33.542  21.010  1.00 84.26  ? 391 VAL A CB  1 
ATOM   2837  C CG1 . VAL A 1 391 ? -9.059  34.092  22.081  1.00 80.33  ? 391 VAL A CG1 1 
ATOM   2838  C CG2 . VAL A 1 391 ? -10.194 32.029  21.164  1.00 85.36  ? 391 VAL A CG2 1 
ATOM   2839  N N   . GLY A 1 392 ? -12.652 33.526  22.906  1.00 84.06  ? 392 GLY A N   1 
ATOM   2840  C CA  . GLY A 1 392 ? -13.191 33.556  24.257  1.00 78.34  ? 392 GLY A CA  1 
ATOM   2841  C C   . GLY A 1 392 ? -12.678 32.378  25.084  1.00 78.64  ? 392 GLY A C   1 
ATOM   2842  O O   . GLY A 1 392 ? -12.506 31.281  24.564  1.00 72.81  ? 392 GLY A O   1 
ATOM   2843  N N   . LEU A 1 393 ? -12.438 32.626  26.379  1.00 80.08  ? 393 LEU A N   1 
ATOM   2844  C CA  . LEU A 1 393 ? -11.994 31.589  27.317  1.00 86.58  ? 393 LEU A CA  1 
ATOM   2845  C C   . LEU A 1 393 ? -13.147 31.230  28.264  1.00 92.55  ? 393 LEU A C   1 
ATOM   2846  O O   . LEU A 1 393 ? -13.766 32.121  28.867  1.00 106.54 ? 393 LEU A O   1 
ATOM   2847  C CB  . LEU A 1 393 ? -10.765 32.065  28.101  1.00 86.41  ? 393 LEU A CB  1 
ATOM   2848  C CG  . LEU A 1 393 ? -9.395  31.572  27.607  1.00 83.48  ? 393 LEU A CG  1 
ATOM   2849  C CD1 . LEU A 1 393 ? -9.070  32.032  26.192  1.00 87.04  ? 393 LEU A CD1 1 
ATOM   2850  C CD2 . LEU A 1 393 ? -8.309  32.026  28.561  1.00 82.60  ? 393 LEU A CD2 1 
ATOM   2851  N N   . LEU A 1 394 ? -13.402 29.913  28.413  1.00 81.40  ? 394 LEU A N   1 
ATOM   2852  C CA  . LEU A 1 394 ? -14.513 29.423  29.220  1.00 75.18  ? 394 LEU A CA  1 
ATOM   2853  C C   . LEU A 1 394 ? -13.973 28.612  30.391  1.00 74.60  ? 394 LEU A C   1 
ATOM   2854  O O   . LEU A 1 394 ? -13.002 27.863  30.246  1.00 81.21  ? 394 LEU A O   1 
ATOM   2855  C CB  . LEU A 1 394 ? -15.474 28.597  28.367  1.00 73.84  ? 394 LEU A CB  1 
ATOM   2856  C CG  . LEU A 1 394 ? -16.419 29.395  27.462  1.00 74.42  ? 394 LEU A CG  1 
ATOM   2857  C CD1 . LEU A 1 394 ? -15.720 29.805  26.177  1.00 72.43  ? 394 LEU A CD1 1 
ATOM   2858  C CD2 . LEU A 1 394 ? -17.693 28.614  27.162  1.00 76.00  ? 394 LEU A CD2 1 
ATOM   2859  N N   . ARG A 1 395 ? -14.632 28.757  31.547  1.00 74.61  ? 395 ARG A N   1 
ATOM   2860  C CA  . ARG A 1 395 ? -14.205 28.103  32.772  1.00 77.01  ? 395 ARG A CA  1 
ATOM   2861  C C   . ARG A 1 395 ? -15.027 26.830  32.983  1.00 75.87  ? 395 ARG A C   1 
ATOM   2862  O O   . ARG A 1 395 ? -16.252 26.865  32.927  1.00 72.10  ? 395 ARG A O   1 
ATOM   2863  C CB  . ARG A 1 395 ? -14.375 29.056  33.959  1.00 77.87  ? 395 ARG A CB  1 
ATOM   2864  C CG  . ARG A 1 395 ? -13.360 28.812  35.060  1.00 82.50  ? 395 ARG A CG  1 
ATOM   2865  C CD  . ARG A 1 395 ? -13.368 29.900  36.113  1.00 83.99  ? 395 ARG A CD  1 
ATOM   2866  N NE  . ARG A 1 395 ? -12.153 29.818  36.935  1.00 83.22  ? 395 ARG A NE  1 
ATOM   2867  C CZ  . ARG A 1 395 ? -11.135 30.695  36.912  1.00 78.23  ? 395 ARG A CZ  1 
ATOM   2868  N NH1 . ARG A 1 395 ? -11.267 31.866  36.301  1.00 71.69  ? 395 ARG A NH1 1 
ATOM   2869  N NH2 . ARG A 1 395 ? -10.005 30.406  37.543  1.00 73.77  ? 395 ARG A NH2 1 
ATOM   2870  N N   . ALA A 1 396 ? -14.336 25.714  33.248  1.00 69.88  ? 396 ALA A N   1 
ATOM   2871  C CA  . ALA A 1 396 ? -14.995 24.435  33.473  1.00 75.55  ? 396 ALA A CA  1 
ATOM   2872  C C   . ALA A 1 396 ? -14.649 23.934  34.862  1.00 76.50  ? 396 ALA A C   1 
ATOM   2873  O O   . ALA A 1 396 ? -13.477 23.850  35.210  1.00 80.36  ? 396 ALA A O   1 
ATOM   2874  C CB  . ALA A 1 396 ? -14.571 23.428  32.405  1.00 80.75  ? 396 ALA A CB  1 
ATOM   2875  N N   . ARG A 1 397 ? -15.673 23.556  35.633  1.00 73.74  ? 397 ARG A N   1 
ATOM   2876  C CA  . ARG A 1 397 ? -15.461 23.079  36.999  1.00 79.39  ? 397 ARG A CA  1 
ATOM   2877  C C   . ARG A 1 397 ? -14.797 21.693  36.968  1.00 82.39  ? 397 ARG A C   1 
ATOM   2878  O O   . ARG A 1 397 ? -13.799 21.463  37.664  1.00 74.57  ? 397 ARG A O   1 
ATOM   2879  C CB  . ARG A 1 397 ? -16.750 23.109  37.838  1.00 79.06  ? 397 ARG A CB  1 
ATOM   2880  C CG  . ARG A 1 397 ? -18.044 22.865  37.079  1.00 87.48  ? 397 ARG A CG  1 
ATOM   2881  C CD  . ARG A 1 397 ? -19.270 23.372  37.860  1.00 79.65  ? 397 ARG A CD  1 
ATOM   2882  N NE  . ARG A 1 397 ? -20.233 24.071  36.992  1.00 78.62  ? 397 ARG A NE  1 
ATOM   2883  C CZ  . ARG A 1 397 ? -21.178 23.495  36.229  1.00 78.20  ? 397 ARG A CZ  1 
ATOM   2884  N NH1 . ARG A 1 397 ? -21.325 22.178  36.219  1.00 76.34  ? 397 ARG A NH1 1 
ATOM   2885  N NH2 . ARG A 1 397 ? -21.986 24.251  35.492  1.00 72.81  ? 397 ARG A NH2 1 
ATOM   2886  N N   . ASP A 1 398 ? -15.327 20.794  36.123  1.00 88.01  ? 398 ASP A N   1 
ATOM   2887  C CA  . ASP A 1 398 ? -14.791 19.436  35.992  1.00 79.98  ? 398 ASP A CA  1 
ATOM   2888  C C   . ASP A 1 398 ? -14.803 19.025  34.516  1.00 76.95  ? 398 ASP A C   1 
ATOM   2889  O O   . ASP A 1 398 ? -15.253 19.788  33.655  1.00 77.70  ? 398 ASP A O   1 
ATOM   2890  C CB  . ASP A 1 398 ? -15.562 18.452  36.866  1.00 69.97  ? 398 ASP A CB  1 
ATOM   2891  C CG  . ASP A 1 398 ? -17.072 18.651  36.902  1.00 67.10  ? 398 ASP A CG  1 
ATOM   2892  O OD1 . ASP A 1 398 ? -17.646 19.024  35.856  1.00 73.79  ? 398 ASP A OD1 1 
ATOM   2893  O OD2 . ASP A 1 398 ? -17.658 18.435  37.969  1.00 72.82  ? 398 ASP A OD2 1 
ATOM   2894  N N   . GLU A 1 399 ? -14.330 17.798  34.242  1.00 67.73  ? 399 GLU A N   1 
ATOM   2895  C CA  . GLU A 1 399 ? -14.309 17.265  32.889  1.00 67.31  ? 399 GLU A CA  1 
ATOM   2896  C C   . GLU A 1 399 ? -15.738 17.153  32.350  1.00 69.44  ? 399 GLU A C   1 
ATOM   2897  O O   . GLU A 1 399 ? -15.977 17.400  31.165  1.00 61.98  ? 399 GLU A O   1 
ATOM   2898  C CB  . GLU A 1 399 ? -13.617 15.907  32.855  1.00 72.41  ? 399 GLU A CB  1 
ATOM   2899  C CG  . GLU A 1 399 ? -13.404 15.383  31.435  1.00 78.23  ? 399 GLU A CG  1 
ATOM   2900  C CD  . GLU A 1 399 ? -13.155 13.879  31.335  1.00 80.54  ? 399 GLU A CD  1 
ATOM   2901  O OE1 . GLU A 1 399 ? -12.475 13.314  32.228  1.00 74.78  ? 399 GLU A OE1 1 
ATOM   2902  O OE2 . GLU A 1 399 ? -13.631 13.274  30.330  1.00 80.45  ? 399 GLU A OE2 1 
ATOM   2903  N N   . ALA A 1 400 ? -16.684 16.768  33.229  1.00 69.59  ? 400 ALA A N   1 
ATOM   2904  C CA  . ALA A 1 400 ? -18.080 16.629  32.843  1.00 64.46  ? 400 ALA A CA  1 
ATOM   2905  C C   . ALA A 1 400 ? -18.631 17.983  32.391  1.00 68.34  ? 400 ALA A C   1 
ATOM   2906  O O   . ALA A 1 400 ? -19.348 18.060  31.386  1.00 61.21  ? 400 ALA A O   1 
ATOM   2907  C CB  . ALA A 1 400 ? -18.885 16.045  33.987  1.00 59.76  ? 400 ALA A CB  1 
ATOM   2908  N N   . HIS A 1 401 ? -18.273 19.052  33.133  1.00 72.44  ? 401 HIS A N   1 
ATOM   2909  C CA  . HIS A 1 401 ? -18.681 20.413  32.778  1.00 77.00  ? 401 HIS A CA  1 
ATOM   2910  C C   . HIS A 1 401 ? -17.997 20.837  31.464  1.00 66.46  ? 401 HIS A C   1 
ATOM   2911  O O   . HIS A 1 401 ? -18.640 21.422  30.591  1.00 56.88  ? 401 HIS A O   1 
ATOM   2912  C CB  . HIS A 1 401 ? -18.399 21.400  33.930  1.00 74.69  ? 401 HIS A CB  1 
ATOM   2913  C CG  . HIS A 1 401 ? -18.837 22.814  33.640  1.00 78.27  ? 401 HIS A CG  1 
ATOM   2914  N ND1 . HIS A 1 401 ? -18.128 23.923  34.056  1.00 70.60  ? 401 HIS A ND1 1 
ATOM   2915  C CD2 . HIS A 1 401 ? -19.903 23.295  32.949  1.00 77.48  ? 401 HIS A CD2 1 
ATOM   2916  C CE1 . HIS A 1 401 ? -18.747 25.019  33.645  1.00 68.19  ? 401 HIS A CE1 1 
ATOM   2917  N NE2 . HIS A 1 401 ? -19.827 24.663  32.971  1.00 72.56  ? 401 HIS A NE2 1 
ATOM   2918  N N   . ALA A 1 402 ? -16.692 20.531  31.342  1.00 57.20  ? 402 ALA A N   1 
ATOM   2919  C CA  . ALA A 1 402 ? -15.926 20.850  30.136  1.00 62.66  ? 402 ALA A CA  1 
ATOM   2920  C C   . ALA A 1 402 ? -16.572 20.211  28.889  1.00 62.54  ? 402 ALA A C   1 
ATOM   2921  O O   . ALA A 1 402 ? -16.629 20.844  27.831  1.00 52.50  ? 402 ALA A O   1 
ATOM   2922  C CB  . ALA A 1 402 ? -14.482 20.407  30.304  1.00 60.25  ? 402 ALA A CB  1 
ATOM   2923  N N   . LEU A 1 403 ? -17.064 18.958  29.038  1.00 65.95  ? 403 LEU A N   1 
ATOM   2924  C CA  . LEU A 1 403 ? -17.702 18.229  27.939  1.00 71.31  ? 403 LEU A CA  1 
ATOM   2925  C C   . LEU A 1 403 ? -19.011 18.910  27.544  1.00 65.74  ? 403 LEU A C   1 
ATOM   2926  O O   . LEU A 1 403 ? -19.279 19.082  26.367  1.00 66.63  ? 403 LEU A O   1 
ATOM   2927  C CB  . LEU A 1 403 ? -17.944 16.762  28.306  1.00 76.53  ? 403 LEU A CB  1 
ATOM   2928  C CG  . LEU A 1 403 ? -18.605 15.900  27.216  1.00 75.67  ? 403 LEU A CG  1 
ATOM   2929  C CD1 . LEU A 1 403 ? -17.706 15.806  25.977  1.00 75.87  ? 403 LEU A CD1 1 
ATOM   2930  C CD2 . LEU A 1 403 ? -18.946 14.505  27.740  1.00 74.85  ? 403 LEU A CD2 1 
ATOM   2931  N N   . GLU A 1 404 ? -19.830 19.270  28.544  1.00 75.17  ? 404 GLU A N   1 
ATOM   2932  C CA  . GLU A 1 404 ? -21.113 19.940  28.298  1.00 77.99  ? 404 GLU A CA  1 
ATOM   2933  C C   . GLU A 1 404 ? -20.875 21.261  27.546  1.00 71.64  ? 404 GLU A C   1 
ATOM   2934  O O   . GLU A 1 404 ? -21.584 21.572  26.581  1.00 60.27  ? 404 GLU A O   1 
ATOM   2935  C CB  . GLU A 1 404 ? -21.845 20.170  29.626  1.00 89.08  ? 404 GLU A CB  1 
ATOM   2936  C CG  . GLU A 1 404 ? -23.028 21.141  29.527  1.00 97.85  ? 404 GLU A CG  1 
ATOM   2937  C CD  . GLU A 1 404 ? -23.626 21.587  30.874  1.00 102.57 ? 404 GLU A CD  1 
ATOM   2938  O OE1 . GLU A 1 404 ? -22.862 22.086  31.747  1.00 100.90 ? 404 GLU A OE1 1 
ATOM   2939  O OE2 . GLU A 1 404 ? -24.865 21.473  31.035  1.00 95.94  ? 404 GLU A OE2 1 
ATOM   2940  N N   . LEU A 1 405 ? -19.853 22.006  27.975  1.00 71.03  ? 405 LEU A N   1 
ATOM   2941  C CA  . LEU A 1 405 ? -19.519 23.296  27.317  1.00 72.04  ? 405 LEU A CA  1 
ATOM   2942  C C   . LEU A 1 405 ? -19.219 23.059  25.831  1.00 68.97  ? 405 LEU A C   1 
ATOM   2943  O O   . LEU A 1 405 ? -19.858 23.720  24.987  1.00 70.48  ? 405 LEU A O   1 
ATOM   2944  C CB  . LEU A 1 405 ? -18.319 23.897  28.043  1.00 70.67  ? 405 LEU A CB  1 
ATOM   2945  C CG  . LEU A 1 405 ? -18.589 24.469  29.437  1.00 72.06  ? 405 LEU A CG  1 
ATOM   2946  C CD1 . LEU A 1 405 ? -17.283 24.803  30.130  1.00 72.17  ? 405 LEU A CD1 1 
ATOM   2947  C CD2 . LEU A 1 405 ? -19.465 25.703  29.334  1.00 74.41  ? 405 LEU A CD2 1 
ATOM   2948  N N   . ALA A 1 406 ? -18.283 22.159  25.528  1.00 62.57  ? 406 ALA A N   1 
ATOM   2949  C CA  . ALA A 1 406 ? -17.877 21.919  24.123  1.00 66.49  ? 406 ALA A CA  1 
ATOM   2950  C C   . ALA A 1 406 ? -19.049 21.388  23.301  1.00 64.45  ? 406 ALA A C   1 
ATOM   2951  O O   . ALA A 1 406 ? -19.215 21.818  22.145  1.00 63.88  ? 406 ALA A O   1 
ATOM   2952  C CB  . ALA A 1 406 ? -16.721 20.950  24.104  1.00 68.03  ? 406 ALA A CB  1 
ATOM   2953  N N   . ASN A 1 407 ? -19.842 20.494  23.887  1.00 76.91  ? 407 ASN A N   1 
ATOM   2954  C CA  . ASN A 1 407 ? -20.967 19.839  23.158  1.00 79.21  ? 407 ASN A CA  1 
ATOM   2955  C C   . ASN A 1 407 ? -22.024 20.858  22.715  1.00 81.17  ? 407 ASN A C   1 
ATOM   2956  O O   . ASN A 1 407 ? -22.551 20.693  21.595  1.00 81.11  ? 407 ASN A O   1 
ATOM   2957  C CB  . ASN A 1 407 ? -21.530 18.671  23.958  1.00 76.29  ? 407 ASN A CB  1 
ATOM   2958  C CG  . ASN A 1 407 ? -20.770 17.395  23.685  1.00 77.34  ? 407 ASN A CG  1 
ATOM   2959  O OD1 . ASN A 1 407 ? -21.016 16.373  24.333  1.00 67.58  ? 407 ASN A OD1 1 
ATOM   2960  N ND2 . ASN A 1 407 ? -19.850 17.430  22.733  1.00 82.84  ? 407 ASN A ND2 1 
ATOM   2961  N N   . ALA A 1 408 ? -22.320 21.876  23.524  1.00 87.80  ? 408 ALA A N   1 
ATOM   2962  C CA  . ALA A 1 408 ? -23.456 22.780  23.210  1.00 88.85  ? 408 ALA A CA  1 
ATOM   2963  C C   . ALA A 1 408 ? -23.263 23.492  21.872  1.00 90.03  ? 408 ALA A C   1 
ATOM   2964  O O   . ALA A 1 408 ? -24.262 23.589  21.135  1.00 91.59  ? 408 ALA A O   1 
ATOM   2965  C CB  . ALA A 1 408 ? -23.625 23.784  24.326  1.00 88.49  ? 408 ALA A CB  1 
ATOM   2966  N N   . SER A 1 409 ? -22.048 23.945  21.564  1.00 111.63 ? 409 SER A N   1 
ATOM   2967  C CA  . SER A 1 409 ? -21.768 24.592  20.253  1.00 123.22 ? 409 SER A CA  1 
ATOM   2968  C C   . SER A 1 409 ? -22.990 24.482  19.331  1.00 132.99 ? 409 SER A C   1 
ATOM   2969  O O   . SER A 1 409 ? -22.792 24.603  18.101  1.00 129.32 ? 409 SER A O   1 
ATOM   2970  C CB  . SER A 1 409 ? -20.551 23.996  19.597  1.00 120.62 ? 409 SER A CB  1 
ATOM   2971  O OG  . SER A 1 409 ? -20.360 22.645  19.989  1.00 108.97 ? 409 SER A OG  1 
ATOM   2972  N N   . LEU A 1 413 ? -17.159 21.245  13.661  1.00 115.67 ? 413 LEU A N   1 
ATOM   2973  C CA  . LEU A 1 413 ? -16.400 20.784  12.500  1.00 103.24 ? 413 LEU A CA  1 
ATOM   2974  C C   . LEU A 1 413 ? -15.081 20.160  12.944  1.00 94.40  ? 413 LEU A C   1 
ATOM   2975  O O   . LEU A 1 413 ? -14.742 19.055  12.516  1.00 96.93  ? 413 LEU A O   1 
ATOM   2976  C CB  . LEU A 1 413 ? -16.173 21.930  11.523  1.00 104.30 ? 413 LEU A CB  1 
ATOM   2977  C CG  . LEU A 1 413 ? -17.243 22.089  10.447  1.00 103.79 ? 413 LEU A CG  1 
ATOM   2978  C CD1 . LEU A 1 413 ? -17.140 20.946  9.446   1.00 91.51  ? 413 LEU A CD1 1 
ATOM   2979  C CD2 . LEU A 1 413 ? -18.648 22.153  11.075  1.00 108.54 ? 413 LEU A CD2 1 
ATOM   2980  N N   . SER A 1 414 ? -14.329 20.889  13.786  1.00 74.04  ? 414 SER A N   1 
ATOM   2981  C CA  . SER A 1 414 ? -13.099 20.369  14.358  1.00 64.28  ? 414 SER A CA  1 
ATOM   2982  C C   . SER A 1 414 ? -13.124 20.535  15.865  1.00 52.91  ? 414 SER A C   1 
ATOM   2983  O O   . SER A 1 414 ? -14.018 21.150  16.399  1.00 55.42  ? 414 SER A O   1 
ATOM   2984  C CB  . SER A 1 414 ? -11.903 21.031  13.765  1.00 70.94  ? 414 SER A CB  1 
ATOM   2985  O OG  . SER A 1 414 ? -10.735 20.242  13.983  1.00 79.10  ? 414 SER A OG  1 
ATOM   2986  N N   . SER A 1 415 ? -12.121 19.974  16.526  1.00 52.59  ? 415 SER A N   1 
ATOM   2987  C CA  . SER A 1 415 ? -12.004 20.049  17.965  1.00 52.01  ? 415 SER A CA  1 
ATOM   2988  C C   . SER A 1 415 ? -10.595 19.658  18.377  1.00 54.44  ? 415 SER A C   1 
ATOM   2989  O O   . SER A 1 415 ? -9.850  19.070  17.579  1.00 53.11  ? 415 SER A O   1 
ATOM   2990  C CB  . SER A 1 415 ? -13.047 19.158  18.660  1.00 57.81  ? 415 SER A CB  1 
ATOM   2991  O OG  . SER A 1 415 ? -12.999 17.818  18.176  1.00 54.57  ? 415 SER A OG  1 
ATOM   2992  N N   . ALA A 1 416 ? -10.253 19.947  19.648  1.00 54.28  ? 416 ALA A N   1 
ATOM   2993  C CA  . ALA A 1 416 ? -8.969  19.561  20.195  1.00 51.79  ? 416 ALA A CA  1 
ATOM   2994  C C   . ALA A 1 416 ? -9.075  19.334  21.705  1.00 46.90  ? 416 ALA A C   1 
ATOM   2995  O O   . ALA A 1 416 ? -9.817  20.011  22.393  1.00 43.65  ? 416 ALA A O   1 
ATOM   2996  C CB  . ALA A 1 416 ? -7.938  20.610  19.858  1.00 55.46  ? 416 ALA A CB  1 
ATOM   2997  N N   . VAL A 1 417 ? -8.306  18.367  22.195  1.00 46.04  ? 417 VAL A N   1 
ATOM   2998  C CA  . VAL A 1 417 ? -8.271  18.039  23.605  1.00 52.85  ? 417 VAL A CA  1 
ATOM   2999  C C   . VAL A 1 417 ? -6.815  17.828  24.030  1.00 54.44  ? 417 VAL A C   1 
ATOM   3000  O O   . VAL A 1 417 ? -6.067  17.111  23.361  1.00 48.59  ? 417 VAL A O   1 
ATOM   3001  C CB  . VAL A 1 417 ? -9.124  16.791  23.883  1.00 55.34  ? 417 VAL A CB  1 
ATOM   3002  C CG1 . VAL A 1 417 ? -8.886  16.241  25.284  1.00 52.66  ? 417 VAL A CG1 1 
ATOM   3003  C CG2 . VAL A 1 417 ? -10.605 17.068  23.643  1.00 58.64  ? 417 VAL A CG2 1 
ATOM   3004  N N   . PHE A 1 418 ? -6.427  18.464  25.148  1.00 52.03  ? 418 PHE A N   1 
ATOM   3005  C CA  . PHE A 1 418 ? -5.069  18.371  25.654  1.00 54.58  ? 418 PHE A CA  1 
ATOM   3006  C C   . PHE A 1 418 ? -5.084  17.708  27.020  1.00 54.50  ? 418 PHE A C   1 
ATOM   3007  O O   . PHE A 1 418 ? -5.707  18.208  27.950  1.00 54.80  ? 418 PHE A O   1 
ATOM   3008  C CB  . PHE A 1 418 ? -4.442  19.761  25.691  1.00 59.79  ? 418 PHE A CB  1 
ATOM   3009  C CG  . PHE A 1 418 ? -3.765  20.137  24.387  1.00 58.99  ? 418 PHE A CG  1 
ATOM   3010  C CD1 . PHE A 1 418 ? -4.515  20.570  23.289  1.00 55.87  ? 418 PHE A CD1 1 
ATOM   3011  C CD2 . PHE A 1 418 ? -2.379  20.032  24.252  1.00 56.57  ? 418 PHE A CD2 1 
ATOM   3012  C CE1 . PHE A 1 418 ? -3.893  20.877  22.088  1.00 54.17  ? 418 PHE A CE1 1 
ATOM   3013  C CE2 . PHE A 1 418 ? -1.759  20.358  23.058  1.00 56.47  ? 418 PHE A CE2 1 
ATOM   3014  C CZ  . PHE A 1 418 ? -2.516  20.776  21.974  1.00 56.94  ? 418 PHE A CZ  1 
ATOM   3015  N N   . SER A 1 419 ? -4.411  16.564  27.113  1.00 56.46  ? 419 SER A N   1 
ATOM   3016  C CA  . SER A 1 419 ? -4.312  15.820  28.356  1.00 59.15  ? 419 SER A CA  1 
ATOM   3017  C C   . SER A 1 419 ? -3.146  14.864  28.272  1.00 63.63  ? 419 SER A C   1 
ATOM   3018  O O   . SER A 1 419 ? -2.894  14.268  27.233  1.00 69.07  ? 419 SER A O   1 
ATOM   3019  C CB  . SER A 1 419 ? -5.584  15.084  28.666  1.00 65.16  ? 419 SER A CB  1 
ATOM   3020  O OG  . SER A 1 419 ? -5.315  13.892  29.406  1.00 63.77  ? 419 SER A OG  1 
ATOM   3021  N N   . ARG A 1 420 ? -2.455  14.704  29.373  1.00 69.23  ? 420 ARG A N   1 
ATOM   3022  C CA  . ARG A 1 420 ? -1.208  13.996  29.344  1.00 73.73  ? 420 ARG A CA  1 
ATOM   3023  C C   . ARG A 1 420 ? -1.494  12.500  29.387  1.00 77.90  ? 420 ARG A C   1 
ATOM   3024  O O   . ARG A 1 420 ? -0.671  11.709  28.967  1.00 76.23  ? 420 ARG A O   1 
ATOM   3025  C CB  . ARG A 1 420 ? -0.264  14.553  30.416  1.00 89.25  ? 420 ARG A CB  1 
ATOM   3026  C CG  . ARG A 1 420 ? 0.722   15.529  29.770  1.00 110.94 ? 420 ARG A CG  1 
ATOM   3027  C CD  . ARG A 1 420 ? 1.861   16.134  30.694  1.00 118.92 ? 420 ARG A CD  1 
ATOM   3028  N NE  . ARG A 1 420 ? 3.062   15.289  30.817  1.00 122.69 ? 420 ARG A NE  1 
ATOM   3029  C CZ  . ARG A 1 420 ? 3.715   15.053  31.958  1.00 122.68 ? 420 ARG A CZ  1 
ATOM   3030  N NH1 . ARG A 1 420 ? 3.394   15.717  33.053  1.00 123.48 ? 420 ARG A NH1 1 
ATOM   3031  N NH2 . ARG A 1 420 ? 4.701   14.171  31.992  1.00 115.36 ? 420 ARG A NH2 1 
ATOM   3032  N N   . ASP A 1 421 ? -2.730  12.150  29.797  1.00 83.43  ? 421 ASP A N   1 
ATOM   3033  C CA  . ASP A 1 421 ? -3.246  10.784  29.746  1.00 78.09  ? 421 ASP A CA  1 
ATOM   3034  C C   . ASP A 1 421 ? -4.018  10.570  28.424  1.00 72.07  ? 421 ASP A C   1 
ATOM   3035  O O   . ASP A 1 421 ? -5.137  11.056  28.272  1.00 68.89  ? 421 ASP A O   1 
ATOM   3036  C CB  . ASP A 1 421 ? -4.129  10.525  30.959  1.00 83.47  ? 421 ASP A CB  1 
ATOM   3037  C CG  . ASP A 1 421 ? -4.627  9.104   31.129  1.00 89.92  ? 421 ASP A CG  1 
ATOM   3038  O OD1 . ASP A 1 421 ? -5.357  8.635   30.247  1.00 101.70 ? 421 ASP A OD1 1 
ATOM   3039  O OD2 . ASP A 1 421 ? -4.291  8.486   32.160  1.00 101.66 ? 421 ASP A OD2 1 
ATOM   3040  N N   . LEU A 1 422 ? -3.421  9.807   27.487  1.00 65.31  ? 422 LEU A N   1 
ATOM   3041  C CA  . LEU A 1 422 ? -3.970  9.669   26.141  1.00 67.81  ? 422 LEU A CA  1 
ATOM   3042  C C   . LEU A 1 422 ? -5.303  8.923   26.181  1.00 73.76  ? 422 LEU A C   1 
ATOM   3043  O O   . LEU A 1 422 ? -6.244  9.301   25.474  1.00 60.96  ? 422 LEU A O   1 
ATOM   3044  C CB  . LEU A 1 422 ? -2.972  8.970   25.237  1.00 68.15  ? 422 LEU A CB  1 
ATOM   3045  C CG  . LEU A 1 422 ? -1.725  9.780   24.886  1.00 76.12  ? 422 LEU A CG  1 
ATOM   3046  C CD1 . LEU A 1 422 ? -0.872  9.054   23.860  1.00 83.33  ? 422 LEU A CD1 1 
ATOM   3047  C CD2 . LEU A 1 422 ? -2.098  11.164  24.392  1.00 69.75  ? 422 LEU A CD2 1 
ATOM   3048  N N   . GLU A 1 423 ? -5.377  7.868   27.015  1.00 81.75  ? 423 GLU A N   1 
ATOM   3049  C CA  . GLU A 1 423 ? -6.596  7.072   27.151  1.00 81.99  ? 423 GLU A CA  1 
ATOM   3050  C C   . GLU A 1 423 ? -7.765  7.983   27.541  1.00 70.71  ? 423 GLU A C   1 
ATOM   3051  O O   . GLU A 1 423 ? -8.840  7.932   26.928  1.00 68.40  ? 423 GLU A O   1 
ATOM   3052  C CB  . GLU A 1 423 ? -6.420  5.958   28.185  1.00 86.73  ? 423 GLU A CB  1 
ATOM   3053  C CG  . GLU A 1 423 ? -7.584  4.966   28.203  1.00 95.43  ? 423 GLU A CG  1 
ATOM   3054  C CD  . GLU A 1 423 ? -7.618  4.035   29.408  1.00 102.36 ? 423 GLU A CD  1 
ATOM   3055  O OE1 . GLU A 1 423 ? -6.703  4.124   30.275  1.00 107.54 ? 423 GLU A OE1 1 
ATOM   3056  O OE2 . GLU A 1 423 ? -8.557  3.199   29.472  1.00 94.00  ? 423 GLU A OE2 1 
ATOM   3057  N N   . ARG A 1 424 ? -7.539  8.817   28.563  1.00 66.91  ? 424 ARG A N   1 
ATOM   3058  C CA  . ARG A 1 424 ? -8.529  9.778   29.019  1.00 61.80  ? 424 ARG A CA  1 
ATOM   3059  C C   . ARG A 1 424 ? -8.888  10.750  27.884  1.00 53.04  ? 424 ARG A C   1 
ATOM   3060  O O   . ARG A 1 424 ? -10.057 11.015  27.648  1.00 51.78  ? 424 ARG A O   1 
ATOM   3061  C CB  . ARG A 1 424 ? -7.990  10.509  30.250  1.00 72.29  ? 424 ARG A CB  1 
ATOM   3062  C CG  . ARG A 1 424 ? -8.962  11.525  30.818  1.00 82.81  ? 424 ARG A CG  1 
ATOM   3063  C CD  . ARG A 1 424 ? -8.664  11.855  32.265  1.00 94.27  ? 424 ARG A CD  1 
ATOM   3064  N NE  . ARG A 1 424 ? -8.051  13.178  32.417  1.00 98.65  ? 424 ARG A NE  1 
ATOM   3065  C CZ  . ARG A 1 424 ? -8.707  14.284  32.780  1.00 99.80  ? 424 ARG A CZ  1 
ATOM   3066  N NH1 . ARG A 1 424 ? -10.036 14.295  32.822  1.00 98.05  ? 424 ARG A NH1 1 
ATOM   3067  N NH2 . ARG A 1 424 ? -8.032  15.387  33.058  1.00 107.20 ? 424 ARG A NH2 1 
ATOM   3068  N N   . ALA A 1 425 ? -7.863  11.272  27.186  1.00 52.20  ? 425 ALA A N   1 
ATOM   3069  C CA  . ALA A 1 425 ? -8.068  12.241  26.110  1.00 50.63  ? 425 ALA A CA  1 
ATOM   3070  C C   . ALA A 1 425 ? -8.930  11.636  25.006  1.00 52.49  ? 425 ALA A C   1 
ATOM   3071  O O   . ALA A 1 425 ? -9.859  12.270  24.519  1.00 46.53  ? 425 ALA A O   1 
ATOM   3072  C CB  . ALA A 1 425 ? -6.741  12.707  25.570  1.00 52.29  ? 425 ALA A CB  1 
ATOM   3073  N N   . VAL A 1 426 ? -8.628  10.392  24.626  1.00 55.35  ? 426 VAL A N   1 
ATOM   3074  C CA  . VAL A 1 426 ? -9.356  9.746   23.541  1.00 57.57  ? 426 VAL A CA  1 
ATOM   3075  C C   . VAL A 1 426 ? -10.814 9.484   23.981  1.00 59.42  ? 426 VAL A C   1 
ATOM   3076  O O   . VAL A 1 426 ? -11.740 9.688   23.195  1.00 51.22  ? 426 VAL A O   1 
ATOM   3077  C CB  . VAL A 1 426 ? -8.644  8.457   23.075  1.00 58.09  ? 426 VAL A CB  1 
ATOM   3078  C CG1 . VAL A 1 426 ? -9.469  7.679   22.054  1.00 63.05  ? 426 VAL A CG1 1 
ATOM   3079  C CG2 . VAL A 1 426 ? -7.261  8.759   22.507  1.00 58.38  ? 426 VAL A CG2 1 
ATOM   3080  N N   . ARG A 1 427 ? -11.006 9.042   25.249  1.00 61.26  ? 427 ARG A N   1 
ATOM   3081  C CA  . ARG A 1 427 ? -12.352 8.816   25.807  1.00 59.83  ? 427 ARG A CA  1 
ATOM   3082  C C   . ARG A 1 427 ? -13.216 10.071  25.652  1.00 53.02  ? 427 ARG A C   1 
ATOM   3083  O O   . ARG A 1 427 ? -14.363 9.984   25.200  1.00 55.78  ? 427 ARG A O   1 
ATOM   3084  C CB  . ARG A 1 427 ? -12.314 8.436   27.294  1.00 70.59  ? 427 ARG A CB  1 
ATOM   3085  C CG  . ARG A 1 427 ? -12.701 6.995   27.595  1.00 72.39  ? 427 ARG A CG  1 
ATOM   3086  C CD  . ARG A 1 427 ? -13.018 6.780   29.086  1.00 76.74  ? 427 ARG A CD  1 
ATOM   3087  N NE  . ARG A 1 427 ? -12.036 7.414   29.983  1.00 81.22  ? 427 ARG A NE  1 
ATOM   3088  C CZ  . ARG A 1 427 ? -11.018 6.782   30.594  1.00 86.15  ? 427 ARG A CZ  1 
ATOM   3089  N NH1 . ARG A 1 427 ? -10.866 5.473   30.454  1.00 96.22  ? 427 ARG A NH1 1 
ATOM   3090  N NH2 . ARG A 1 427 ? -10.138 7.472   31.310  1.00 81.21  ? 427 ARG A NH2 1 
ATOM   3091  N N   . PHE A 1 428 ? -12.654 11.231  26.051  1.00 45.38  ? 428 PHE A N   1 
ATOM   3092  C CA  . PHE A 1 428 ? -13.346 12.504  25.959  1.00 47.03  ? 428 PHE A CA  1 
ATOM   3093  C C   . PHE A 1 428 ? -13.675 12.814  24.501  1.00 43.57  ? 428 PHE A C   1 
ATOM   3094  O O   . PHE A 1 428 ? -14.796 13.185  24.190  1.00 43.16  ? 428 PHE A O   1 
ATOM   3095  C CB  . PHE A 1 428 ? -12.483 13.600  26.611  1.00 55.24  ? 428 PHE A CB  1 
ATOM   3096  C CG  . PHE A 1 428 ? -13.109 14.999  26.603  1.00 52.89  ? 428 PHE A CG  1 
ATOM   3097  C CD1 . PHE A 1 428 ? -13.825 15.475  27.708  1.00 54.45  ? 428 PHE A CD1 1 
ATOM   3098  C CD2 . PHE A 1 428 ? -12.999 15.825  25.485  1.00 47.33  ? 428 PHE A CD2 1 
ATOM   3099  C CE1 . PHE A 1 428 ? -14.392 16.749  27.694  1.00 57.54  ? 428 PHE A CE1 1 
ATOM   3100  C CE2 . PHE A 1 428 ? -13.551 17.102  25.481  1.00 51.03  ? 428 PHE A CE2 1 
ATOM   3101  C CZ  . PHE A 1 428 ? -14.267 17.554  26.574  1.00 56.18  ? 428 PHE A CZ  1 
ATOM   3102  N N   . ALA A 1 429 ? -12.674 12.664  23.612  1.00 50.87  ? 429 ALA A N   1 
ATOM   3103  C CA  . ALA A 1 429 ? -12.801 13.049  22.197  1.00 55.99  ? 429 ALA A CA  1 
ATOM   3104  C C   . ALA A 1 429 ? -13.985 12.329  21.526  1.00 53.48  ? 429 ALA A C   1 
ATOM   3105  O O   . ALA A 1 429 ? -14.715 12.922  20.718  1.00 46.64  ? 429 ALA A O   1 
ATOM   3106  C CB  . ALA A 1 429 ? -11.500 12.757  21.465  1.00 58.42  ? 429 ALA A CB  1 
ATOM   3107  N N   . ARG A 1 430 ? -14.168 11.053  21.856  1.00 54.63  ? 430 ARG A N   1 
ATOM   3108  C CA  . ARG A 1 430 ? -15.201 10.251  21.212  1.00 61.25  ? 430 ARG A CA  1 
ATOM   3109  C C   . ARG A 1 430 ? -16.596 10.748  21.621  1.00 68.09  ? 430 ARG A C   1 
ATOM   3110  O O   . ARG A 1 430 ? -17.555 10.601  20.858  1.00 59.61  ? 430 ARG A O   1 
ATOM   3111  C CB  . ARG A 1 430 ? -14.999 8.779   21.534  1.00 56.73  ? 430 ARG A CB  1 
ATOM   3112  C CG  . ARG A 1 430 ? -13.647 8.258   21.062  1.00 57.37  ? 430 ARG A CG  1 
ATOM   3113  C CD  . ARG A 1 430 ? -13.632 6.756   20.950  1.00 56.85  ? 430 ARG A CD  1 
ATOM   3114  N NE  . ARG A 1 430 ? -14.709 6.329   20.054  1.00 55.01  ? 430 ARG A NE  1 
ATOM   3115  C CZ  . ARG A 1 430 ? -15.207 5.136   20.025  1.00 51.84  ? 430 ARG A CZ  1 
ATOM   3116  N NH1 . ARG A 1 430 ? -14.624 4.164   20.716  1.00 53.41  ? 430 ARG A NH1 1 
ATOM   3117  N NH2 . ARG A 1 430 ? -16.269 4.892   19.278  1.00 48.60  ? 430 ARG A NH2 1 
ATOM   3118  N N   . GLN A 1 431 ? -16.699 11.359  22.815  1.00 74.30  ? 431 GLN A N   1 
ATOM   3119  C CA  . GLN A 1 431 ? -17.982 11.856  23.305  1.00 63.73  ? 431 GLN A CA  1 
ATOM   3120  C C   . GLN A 1 431 ? -18.297 13.212  22.671  1.00 63.74  ? 431 GLN A C   1 
ATOM   3121  O O   . GLN A 1 431 ? -19.456 13.618  22.645  1.00 63.19  ? 431 GLN A O   1 
ATOM   3122  C CB  . GLN A 1 431 ? -18.022 11.957  24.827  1.00 62.10  ? 431 GLN A CB  1 
ATOM   3123  C CG  . GLN A 1 431 ? -17.768 10.638  25.546  1.00 62.06  ? 431 GLN A CG  1 
ATOM   3124  C CD  . GLN A 1 431 ? -18.175 10.682  26.997  1.00 68.34  ? 431 GLN A CD  1 
ATOM   3125  O OE1 . GLN A 1 431 ? -17.343 10.802  27.906  1.00 72.25  ? 431 GLN A OE1 1 
ATOM   3126  N NE2 . GLN A 1 431 ? -19.475 10.645  27.226  1.00 79.57  ? 431 GLN A NE2 1 
ATOM   3127  N N   . LEU A 1 432 ? -17.259 13.918  22.169  1.00 64.88  ? 432 LEU A N   1 
ATOM   3128  C CA  . LEU A 1 432 ? -17.485 15.128  21.368  1.00 61.79  ? 432 LEU A CA  1 
ATOM   3129  C C   . LEU A 1 432 ? -18.247 14.721  20.127  1.00 65.00  ? 432 LEU A C   1 
ATOM   3130  O O   . LEU A 1 432 ? -17.834 13.805  19.437  1.00 74.12  ? 432 LEU A O   1 
ATOM   3131  C CB  . LEU A 1 432 ? -16.180 15.836  20.974  1.00 55.38  ? 432 LEU A CB  1 
ATOM   3132  C CG  . LEU A 1 432 ? -15.256 16.263  22.120  1.00 57.23  ? 432 LEU A CG  1 
ATOM   3133  C CD1 . LEU A 1 432 ? -13.922 16.735  21.595  1.00 53.61  ? 432 LEU A CD1 1 
ATOM   3134  C CD2 . LEU A 1 432 ? -15.891 17.340  22.961  1.00 57.99  ? 432 LEU A CD2 1 
ATOM   3135  N N   . ARG A 1 433 ? -19.335 15.421  19.811  1.00 72.81  ? 433 ARG A N   1 
ATOM   3136  C CA  . ARG A 1 433 ? -19.910 15.264  18.491  1.00 84.54  ? 433 ARG A CA  1 
ATOM   3137  C C   . ARG A 1 433 ? -19.323 16.326  17.587  1.00 81.95  ? 433 ARG A C   1 
ATOM   3138  O O   . ARG A 1 433 ? -19.904 17.382  17.396  1.00 90.10  ? 433 ARG A O   1 
ATOM   3139  C CB  . ARG A 1 433 ? -21.427 15.162  18.466  1.00 97.89  ? 433 ARG A CB  1 
ATOM   3140  N N   . ALA A 1 434 ? -18.100 16.032  17.118  1.00 86.87  ? 434 ALA A N   1 
ATOM   3141  C CA  . ALA A 1 434 ? -17.452 16.724  16.014  1.00 83.33  ? 434 ALA A CA  1 
ATOM   3142  C C   . ALA A 1 434 ? -17.019 15.684  14.974  1.00 73.12  ? 434 ALA A C   1 
ATOM   3143  O O   . ALA A 1 434 ? -16.917 14.503  15.288  1.00 65.95  ? 434 ALA A O   1 
ATOM   3144  C CB  . ALA A 1 434 ? -16.248 17.526  16.542  1.00 83.15  ? 434 ALA A CB  1 
ATOM   3145  N N   . GLY A 1 435 ? -16.732 16.141  13.752  1.00 71.60  ? 435 GLY A N   1 
ATOM   3146  C CA  . GLY A 1 435 ? -16.228 15.268  12.700  1.00 73.15  ? 435 GLY A CA  1 
ATOM   3147  C C   . GLY A 1 435 ? -14.757 14.901  12.923  1.00 70.83  ? 435 GLY A C   1 
ATOM   3148  O O   . GLY A 1 435 ? -14.335 13.791  12.582  1.00 62.24  ? 435 GLY A O   1 
ATOM   3149  N N   . MET A 1 436 ? -13.982 15.860  13.474  1.00 73.09  ? 436 MET A N   1 
ATOM   3150  C CA  . MET A 1 436 ? -12.557 15.669  13.716  1.00 70.03  ? 436 MET A CA  1 
ATOM   3151  C C   . MET A 1 436 ? -12.192 16.164  15.126  1.00 62.20  ? 436 MET A C   1 
ATOM   3152  O O   . MET A 1 436 ? -12.683 17.189  15.580  1.00 51.13  ? 436 MET A O   1 
ATOM   3153  C CB  . MET A 1 436 ? -11.719 16.428  12.686  1.00 69.93  ? 436 MET A CB  1 
ATOM   3154  C CG  . MET A 1 436 ? -12.174 16.241  11.262  1.00 87.03  ? 436 MET A CG  1 
ATOM   3155  S SD  . MET A 1 436 ? -11.231 17.234  10.081  1.00 110.97 ? 436 MET A SD  1 
ATOM   3156  C CE  . MET A 1 436 ? -9.556  17.133  10.730  1.00 107.38 ? 436 MET A CE  1 
ATOM   3157  N N   . THR A 1 437 ? -11.294 15.422  15.790  1.00 57.57  ? 437 THR A N   1 
ATOM   3158  C CA  . THR A 1 437 ? -10.671 15.863  17.027  1.00 58.01  ? 437 THR A CA  1 
ATOM   3159  C C   . THR A 1 437 ? -9.155  15.696  16.909  1.00 54.13  ? 437 THR A C   1 
ATOM   3160  O O   . THR A 1 437 ? -8.680  14.655  16.472  1.00 46.38  ? 437 THR A O   1 
ATOM   3161  C CB  . THR A 1 437 ? -11.221 15.062  18.218  1.00 57.02  ? 437 THR A CB  1 
ATOM   3162  O OG1 . THR A 1 437 ? -12.652 15.183  18.220  1.00 50.93  ? 437 THR A OG1 1 
ATOM   3163  C CG2 . THR A 1 437 ? -10.660 15.565  19.540  1.00 55.13  ? 437 THR A CG2 1 
ATOM   3164  N N   . HIS A 1 438 ? -8.409  16.718  17.351  1.00 52.97  ? 438 HIS A N   1 
ATOM   3165  C CA  . HIS A 1 438 ? -6.957  16.629  17.466  1.00 56.34  ? 438 HIS A CA  1 
ATOM   3166  C C   . HIS A 1 438 ? -6.575  16.502  18.941  1.00 53.97  ? 438 HIS A C   1 
ATOM   3167  O O   . HIS A 1 438 ? -6.972  17.317  19.756  1.00 60.31  ? 438 HIS A O   1 
ATOM   3168  C CB  . HIS A 1 438 ? -6.282  17.861  16.859  1.00 64.49  ? 438 HIS A CB  1 
ATOM   3169  C CG  . HIS A 1 438 ? -6.564  18.083  15.421  1.00 72.16  ? 438 HIS A CG  1 
ATOM   3170  N ND1 . HIS A 1 438 ? -6.574  17.063  14.498  1.00 78.25  ? 438 HIS A ND1 1 
ATOM   3171  C CD2 . HIS A 1 438 ? -6.797  19.217  14.729  1.00 80.80  ? 438 HIS A CD2 1 
ATOM   3172  C CE1 . HIS A 1 438 ? -6.828  17.561  13.296  1.00 81.97  ? 438 HIS A CE1 1 
ATOM   3173  N NE2 . HIS A 1 438 ? -6.973  18.868  13.413  1.00 86.19  ? 438 HIS A NE2 1 
ATOM   3174  N N   . VAL A 1 439 ? -5.807  15.472  19.269  1.00 51.93  ? 439 VAL A N   1 
ATOM   3175  C CA  . VAL A 1 439 ? -5.372  15.249  20.634  1.00 54.32  ? 439 VAL A CA  1 
ATOM   3176  C C   . VAL A 1 439 ? -3.907  15.658  20.722  1.00 58.71  ? 439 VAL A C   1 
ATOM   3177  O O   . VAL A 1 439 ? -3.076  15.114  20.008  1.00 54.67  ? 439 VAL A O   1 
ATOM   3178  C CB  . VAL A 1 439 ? -5.586  13.779  21.078  1.00 55.37  ? 439 VAL A CB  1 
ATOM   3179  C CG1 . VAL A 1 439 ? -4.986  13.492  22.444  1.00 56.96  ? 439 VAL A CG1 1 
ATOM   3180  C CG2 . VAL A 1 439 ? -7.052  13.392  21.073  1.00 57.79  ? 439 VAL A CG2 1 
ATOM   3181  N N   . ASN A 1 440 ? -3.621  16.662  21.577  1.00 64.36  ? 440 ASN A N   1 
ATOM   3182  C CA  . ASN A 1 440 ? -2.256  17.121  21.846  1.00 65.34  ? 440 ASN A CA  1 
ATOM   3183  C C   . ASN A 1 440 ? -1.581  17.604  20.548  1.00 63.37  ? 440 ASN A C   1 
ATOM   3184  O O   . ASN A 1 440 ? -0.385  17.432  20.387  1.00 51.48  ? 440 ASN A O   1 
ATOM   3185  C CB  . ASN A 1 440 ? -1.412  16.036  22.523  1.00 64.07  ? 440 ASN A CB  1 
ATOM   3186  C CG  . ASN A 1 440 ? -1.916  15.666  23.909  1.00 66.69  ? 440 ASN A CG  1 
ATOM   3187  O OD1 . ASN A 1 440 ? -2.816  16.310  24.452  1.00 64.03  ? 440 ASN A OD1 1 
ATOM   3188  N ND2 . ASN A 1 440 ? -1.339  14.637  24.498  1.00 71.70  ? 440 ASN A ND2 1 
ATOM   3189  N N   . ASP A 1 441 ? -2.363  18.222  19.640  1.00 69.51  ? 441 ASP A N   1 
ATOM   3190  C CA  . ASP A 1 441 ? -1.818  18.776  18.403  1.00 88.30  ? 441 ASP A CA  1 
ATOM   3191  C C   . ASP A 1 441 ? -2.232  20.252  18.270  1.00 90.79  ? 441 ASP A C   1 
ATOM   3192  O O   . ASP A 1 441 ? -3.429  20.504  17.921  1.00 82.52  ? 441 ASP A O   1 
ATOM   3193  C CB  . ASP A 1 441 ? -2.244  17.970  17.188  1.00 104.60 ? 441 ASP A CB  1 
ATOM   3194  C CG  . ASP A 1 441 ? -1.758  18.511  15.846  1.00 116.72 ? 441 ASP A CG  1 
ATOM   3195  O OD1 . ASP A 1 441 ? -2.422  18.236  14.835  1.00 126.55 ? 441 ASP A OD1 1 
ATOM   3196  O OD2 . ASP A 1 441 ? -0.702  19.191  15.827  1.00 118.41 ? 441 ASP A OD2 1 
ATOM   3197  N N   . GLY A 1 461 ? -5.753  13.195  5.775   1.00 130.82 ? 461 GLY A N   1 
ATOM   3198  C CA  . GLY A 1 461 ? -6.927  13.496  6.577   1.00 137.89 ? 461 GLY A CA  1 
ATOM   3199  C C   . GLY A 1 461 ? -8.106  13.878  5.691   1.00 136.75 ? 461 GLY A C   1 
ATOM   3200  O O   . GLY A 1 461 ? -8.049  14.870  4.974   1.00 150.62 ? 461 GLY A O   1 
ATOM   3201  N N   . ARG A 1 462 ? -9.163  13.071  5.738   1.00 127.21 ? 462 ARG A N   1 
ATOM   3202  C CA  . ARG A 1 462 ? -10.259 13.188  4.793   1.00 124.02 ? 462 ARG A CA  1 
ATOM   3203  C C   . ARG A 1 462 ? -9.684  13.257  3.391   1.00 117.43 ? 462 ARG A C   1 
ATOM   3204  O O   . ARG A 1 462 ? -8.703  12.584  3.099   1.00 138.44 ? 462 ARG A O   1 
ATOM   3205  C CB  . ARG A 1 462 ? -11.130 14.379  5.174   1.00 123.39 ? 462 ARG A CB  1 
ATOM   3206  C CG  . ARG A 1 462 ? -12.075 13.977  6.289   1.00 119.59 ? 462 ARG A CG  1 
ATOM   3207  C CD  . ARG A 1 462 ? -12.914 15.107  6.877   1.00 123.04 ? 462 ARG A CD  1 
ATOM   3208  N NE  . ARG A 1 462 ? -13.841 15.708  5.911   1.00 127.73 ? 462 ARG A NE  1 
ATOM   3209  C CZ  . ARG A 1 462 ? -13.660 16.901  5.375   1.00 129.10 ? 462 ARG A CZ  1 
ATOM   3210  N NH1 . ARG A 1 462 ? -14.455 17.330  4.417   1.00 137.73 ? 462 ARG A NH1 1 
ATOM   3211  N NH2 . ARG A 1 462 ? -12.637 17.636  5.759   1.00 116.91 ? 462 ARG A NH2 1 
ATOM   3212  N N   . PHE A 1 463 ? -10.286 14.071  2.528   1.00 99.04  ? 463 PHE A N   1 
ATOM   3213  C CA  . PHE A 1 463 ? -9.883  14.099  1.131   1.00 104.47 ? 463 PHE A CA  1 
ATOM   3214  C C   . PHE A 1 463 ? -9.722  12.646  0.645   1.00 103.13 ? 463 PHE A C   1 
ATOM   3215  O O   . PHE A 1 463 ? -10.699 11.910  0.601   1.00 128.14 ? 463 PHE A O   1 
ATOM   3216  C CB  . PHE A 1 463 ? -8.609  14.941  0.940   1.00 100.89 ? 463 PHE A CB  1 
ATOM   3217  C CG  . PHE A 1 463 ? -8.299  15.252  -0.523  1.00 97.48  ? 463 PHE A CG  1 
ATOM   3218  C CD1 . PHE A 1 463 ? -9.089  16.150  -1.236  1.00 94.50  ? 463 PHE A CD1 1 
ATOM   3219  C CD2 . PHE A 1 463 ? -7.255  14.609  -1.202  1.00 97.79  ? 463 PHE A CD2 1 
ATOM   3220  C CE1 . PHE A 1 463 ? -8.836  16.409  -2.579  1.00 91.87  ? 463 PHE A CE1 1 
ATOM   3221  C CE2 . PHE A 1 463 ? -7.013  14.873  -2.546  1.00 90.07  ? 463 PHE A CE2 1 
ATOM   3222  C CZ  . PHE A 1 463 ? -7.794  15.775  -3.225  1.00 86.18  ? 463 PHE A CZ  1 
ATOM   3223  N N   . ASN A 1 464 ? -8.471  12.243  0.311   1.00 77.85  ? 464 ASN A N   1 
ATOM   3224  C CA  . ASN A 1 464 ? -8.116  10.842  0.031   1.00 81.06  ? 464 ASN A CA  1 
ATOM   3225  C C   . ASN A 1 464 ? -8.917  10.300  -1.162  1.00 71.10  ? 464 ASN A C   1 
ATOM   3226  O O   . ASN A 1 464 ? -9.948  10.846  -1.544  1.00 71.35  ? 464 ASN A O   1 
ATOM   3227  C CB  . ASN A 1 464 ? -8.242  9.945   1.279   1.00 84.59  ? 464 ASN A CB  1 
ATOM   3228  C CG  . ASN A 1 464 ? -9.660  9.454   1.540   1.00 90.30  ? 464 ASN A CG  1 
ATOM   3229  O OD1 . ASN A 1 464 ? -10.279 8.818   0.674   1.00 88.58  ? 464 ASN A OD1 1 
ATOM   3230  N ND2 . ASN A 1 464 ? -10.174 9.697   2.742   1.00 98.12  ? 464 ASN A ND2 1 
ATOM   3231  N N   . GLY A 1 465 ? -8.433  9.189   -1.717  1.00 71.57  ? 465 GLY A N   1 
ATOM   3232  C CA  . GLY A 1 465 ? -9.026  8.587   -2.903  1.00 73.07  ? 465 GLY A CA  1 
ATOM   3233  C C   . GLY A 1 465 ? -10.438 8.073   -2.636  1.00 69.08  ? 465 GLY A C   1 
ATOM   3234  O O   . GLY A 1 465 ? -11.337 8.290   -3.435  1.00 70.14  ? 465 GLY A O   1 
ATOM   3235  N N   . ASP A 1 466 ? -10.627 7.434   -1.484  1.00 68.02  ? 466 ASP A N   1 
ATOM   3236  C CA  . ASP A 1 466 ? -11.893 6.802   -1.161  1.00 76.78  ? 466 ASP A CA  1 
ATOM   3237  C C   . ASP A 1 466 ? -13.021 7.837   -1.242  1.00 72.56  ? 466 ASP A C   1 
ATOM   3238  O O   . ASP A 1 466 ? -14.010 7.620   -1.946  1.00 62.13  ? 466 ASP A O   1 
ATOM   3239  C CB  . ASP A 1 466 ? -11.821 6.093   0.185   1.00 86.12  ? 466 ASP A CB  1 
ATOM   3240  C CG  . ASP A 1 466 ? -10.812 4.948   0.266   1.00 82.69  ? 466 ASP A CG  1 
ATOM   3241  O OD1 . ASP A 1 466 ? -10.420 4.425   -0.803  1.00 66.88  ? 466 ASP A OD1 1 
ATOM   3242  O OD2 . ASP A 1 466 ? -10.414 4.605   1.385   1.00 90.84  ? 466 ASP A OD2 1 
ATOM   3243  N N   . TRP A 1 467 ? -12.866 8.962   -0.520  1.00 66.59  ? 467 TRP A N   1 
ATOM   3244  C CA  . TRP A 1 467 ? -13.898 9.990   -0.497  1.00 63.28  ? 467 TRP A CA  1 
ATOM   3245  C C   . TRP A 1 467 ? -14.094 10.588  -1.898  1.00 58.53  ? 467 TRP A C   1 
ATOM   3246  O O   . TRP A 1 467 ? -15.223 10.760  -2.352  1.00 56.15  ? 467 TRP A O   1 
ATOM   3247  C CB  . TRP A 1 467 ? -13.564 11.087  0.520   1.00 64.19  ? 467 TRP A CB  1 
ATOM   3248  C CG  . TRP A 1 467 ? -14.285 12.381  0.245   1.00 68.46  ? 467 TRP A CG  1 
ATOM   3249  C CD1 . TRP A 1 467 ? -15.547 12.710  0.636   1.00 73.30  ? 467 TRP A CD1 1 
ATOM   3250  C CD2 . TRP A 1 467 ? -13.800 13.503  -0.531  1.00 69.23  ? 467 TRP A CD2 1 
ATOM   3251  N NE1 . TRP A 1 467 ? -15.877 13.960  0.178   1.00 72.59  ? 467 TRP A NE1 1 
ATOM   3252  C CE2 . TRP A 1 467 ? -14.827 14.473  -0.540  1.00 69.46  ? 467 TRP A CE2 1 
ATOM   3253  C CE3 . TRP A 1 467 ? -12.604 13.788  -1.198  1.00 72.91  ? 467 TRP A CE3 1 
ATOM   3254  C CZ2 . TRP A 1 467 ? -14.690 15.707  -1.189  1.00 65.00  ? 467 TRP A CZ2 1 
ATOM   3255  C CZ3 . TRP A 1 467 ? -12.471 15.006  -1.844  1.00 72.78  ? 467 TRP A CZ3 1 
ATOM   3256  C CH2 . TRP A 1 467 ? -13.504 15.950  -1.839  1.00 66.51  ? 467 TRP A CH2 1 
ATOM   3257  N N   . ALA A 1 468 ? -12.990 10.920  -2.561  1.00 51.56  ? 468 ALA A N   1 
ATOM   3258  C CA  . ALA A 1 468 ? -13.043 11.645  -3.817  1.00 57.51  ? 468 ALA A CA  1 
ATOM   3259  C C   . ALA A 1 468 ? -13.761 10.822  -4.889  1.00 54.25  ? 468 ALA A C   1 
ATOM   3260  O O   . ALA A 1 468 ? -14.558 11.356  -5.652  1.00 57.87  ? 468 ALA A O   1 
ATOM   3261  C CB  . ALA A 1 468 ? -11.643 12.018  -4.250  1.00 63.66  ? 468 ALA A CB  1 
ATOM   3262  N N   . ILE A 1 469 ? -13.447 9.528   -4.962  1.00 54.68  ? 469 ILE A N   1 
ATOM   3263  C CA  . ILE A 1 469 ? -13.986 8.672   -6.009  1.00 54.89  ? 469 ILE A CA  1 
ATOM   3264  C C   . ILE A 1 469 ? -15.489 8.552   -5.817  1.00 50.31  ? 469 ILE A C   1 
ATOM   3265  O O   . ILE A 1 469 ? -16.238 8.695   -6.765  1.00 56.26  ? 469 ILE A O   1 
ATOM   3266  C CB  . ILE A 1 469 ? -13.289 7.301   -6.018  1.00 61.90  ? 469 ILE A CB  1 
ATOM   3267  C CG1 . ILE A 1 469 ? -11.799 7.449   -6.243  1.00 66.55  ? 469 ILE A CG1 1 
ATOM   3268  C CG2 . ILE A 1 469 ? -13.925 6.357   -7.040  1.00 68.17  ? 469 ILE A CG2 1 
ATOM   3269  C CD1 . ILE A 1 469 ? -11.103 6.157   -6.617  1.00 74.76  ? 469 ILE A CD1 1 
ATOM   3270  N N   . GLU A 1 470 ? -15.921 8.349   -4.569  1.00 46.28  ? 470 GLU A N   1 
ATOM   3271  C CA  . GLU A 1 470 ? -17.336 8.249   -4.260  1.00 54.14  ? 470 GLU A CA  1 
ATOM   3272  C C   . GLU A 1 470 ? -18.046 9.549   -4.644  1.00 57.01  ? 470 GLU A C   1 
ATOM   3273  O O   . GLU A 1 470 ? -19.110 9.515   -5.238  1.00 73.43  ? 470 GLU A O   1 
ATOM   3274  C CB  . GLU A 1 470 ? -17.559 7.925   -2.779  1.00 60.88  ? 470 GLU A CB  1 
ATOM   3275  C CG  . GLU A 1 470 ? -19.032 7.946   -2.350  1.00 72.67  ? 470 GLU A CG  1 
ATOM   3276  C CD  . GLU A 1 470 ? -19.824 6.668   -2.658  1.00 92.57  ? 470 GLU A CD  1 
ATOM   3277  O OE1 . GLU A 1 470 ? -19.240 5.570   -2.497  1.00 107.05 ? 470 GLU A OE1 1 
ATOM   3278  O OE2 . GLU A 1 470 ? -21.033 6.765   -3.018  1.00 98.17  ? 470 GLU A OE2 1 
ATOM   3279  N N   . GLU A 1 471 ? -17.443 10.680  -4.294  1.00 58.32  ? 471 GLU A N   1 
ATOM   3280  C CA  . GLU A 1 471 ? -18.085 11.982  -4.433  1.00 59.16  ? 471 GLU A CA  1 
ATOM   3281  C C   . GLU A 1 471 ? -18.315 12.329  -5.919  1.00 47.56  ? 471 GLU A C   1 
ATOM   3282  O O   . GLU A 1 471 ? -19.369 12.816  -6.273  1.00 46.80  ? 471 GLU A O   1 
ATOM   3283  C CB  . GLU A 1 471 ? -17.244 13.058  -3.738  1.00 64.17  ? 471 GLU A CB  1 
ATOM   3284  C CG  . GLU A 1 471 ? -17.884 14.439  -3.754  1.00 69.69  ? 471 GLU A CG  1 
ATOM   3285  C CD  . GLU A 1 471 ? -18.667 14.745  -2.503  1.00 79.20  ? 471 GLU A CD  1 
ATOM   3286  O OE1 . GLU A 1 471 ? -18.056 15.225  -1.541  1.00 87.75  ? 471 GLU A OE1 1 
ATOM   3287  O OE2 . GLU A 1 471 ? -19.880 14.469  -2.477  1.00 91.88  ? 471 GLU A OE2 1 
ATOM   3288  N N   . PHE A 1 472 ? -17.315 12.103  -6.773  1.00 45.24  ? 472 PHE A N   1 
ATOM   3289  C CA  . PHE A 1 472 ? -17.352 12.648  -8.136  1.00 45.97  ? 472 PHE A CA  1 
ATOM   3290  C C   . PHE A 1 472 ? -17.579 11.539  -9.176  1.00 42.95  ? 472 PHE A C   1 
ATOM   3291  O O   . PHE A 1 472 ? -17.412 11.780  -10.364 1.00 43.79  ? 472 PHE A O   1 
ATOM   3292  C CB  . PHE A 1 472 ? -16.062 13.425  -8.442  1.00 43.54  ? 472 PHE A CB  1 
ATOM   3293  C CG  . PHE A 1 472 ? -15.851 14.598  -7.519  1.00 46.05  ? 472 PHE A CG  1 
ATOM   3294  C CD1 . PHE A 1 472 ? -16.767 15.639  -7.478  1.00 49.83  ? 472 PHE A CD1 1 
ATOM   3295  C CD2 . PHE A 1 472 ? -14.774 14.634  -6.651  1.00 50.55  ? 472 PHE A CD2 1 
ATOM   3296  C CE1 . PHE A 1 472 ? -16.596 16.696  -6.602  1.00 49.95  ? 472 PHE A CE1 1 
ATOM   3297  C CE2 . PHE A 1 472 ? -14.606 15.694  -5.771  1.00 52.19  ? 472 PHE A CE2 1 
ATOM   3298  C CZ  . PHE A 1 472 ? -15.514 16.722  -5.749  1.00 50.08  ? 472 PHE A CZ  1 
ATOM   3299  N N   . THR A 1 473 ? -17.978 10.337  -8.737  1.00 43.28  ? 473 THR A N   1 
ATOM   3300  C CA  . THR A 1 473 ? -18.408 9.299   -9.669  1.00 44.87  ? 473 THR A CA  1 
ATOM   3301  C C   . THR A 1 473 ? -19.744 8.731   -9.206  1.00 52.16  ? 473 THR A C   1 
ATOM   3302  O O   . THR A 1 473 ? -20.161 8.942   -8.053  1.00 55.82  ? 473 THR A O   1 
ATOM   3303  C CB  . THR A 1 473 ? -17.345 8.196   -9.800  1.00 46.69  ? 473 THR A CB  1 
ATOM   3304  O OG1 . THR A 1 473 ? -17.316 7.478   -8.578  1.00 50.49  ? 473 THR A OG1 1 
ATOM   3305  C CG2 . THR A 1 473 ? -15.952 8.735   -10.089 1.00 44.99  ? 473 THR A CG2 1 
ATOM   3306  N N   . THR A 1 474 ? -20.403 7.994   -10.112 1.00 54.54  ? 474 THR A N   1 
ATOM   3307  C CA  . THR A 1 474 ? -21.689 7.377   -9.818  1.00 54.82  ? 474 THR A CA  1 
ATOM   3308  C C   . THR A 1 474 ? -21.695 5.942   -10.346 1.00 54.09  ? 474 THR A C   1 
ATOM   3309  O O   . THR A 1 474 ? -20.928 5.590   -11.270 1.00 48.03  ? 474 THR A O   1 
ATOM   3310  C CB  . THR A 1 474 ? -22.830 8.217   -10.413 1.00 53.45  ? 474 THR A CB  1 
ATOM   3311  O OG1 . THR A 1 474 ? -23.982 7.403   -10.266 1.00 73.49  ? 474 THR A OG1 1 
ATOM   3312  C CG2 . THR A 1 474 ? -22.625 8.560   -11.875 1.00 52.70  ? 474 THR A CG2 1 
ATOM   3313  N N   . ASP A 1 475 ? -22.581 5.125   -9.759  1.00 48.97  ? 475 ASP A N   1 
ATOM   3314  C CA  . ASP A 1 475 ? -22.655 3.706   -10.050 1.00 47.06  ? 475 ASP A CA  1 
ATOM   3315  C C   . ASP A 1 475 ? -23.852 3.424   -10.945 1.00 46.04  ? 475 ASP A C   1 
ATOM   3316  O O   . ASP A 1 475 ? -24.954 3.904   -10.692 1.00 43.72  ? 475 ASP A O   1 
ATOM   3317  C CB  . ASP A 1 475 ? -22.750 2.888   -8.774  1.00 53.18  ? 475 ASP A CB  1 
ATOM   3318  C CG  . ASP A 1 475 ? -21.418 2.494   -8.158  1.00 59.22  ? 475 ASP A CG  1 
ATOM   3319  O OD1 . ASP A 1 475 ? -21.405 2.094   -6.992  1.00 70.76  ? 475 ASP A OD1 1 
ATOM   3320  O OD2 . ASP A 1 475 ? -20.430 2.559   -8.859  1.00 67.93  ? 475 ASP A OD2 1 
ATOM   3321  N N   . HIS A 1 476 ? -23.637 2.564   -11.940 1.00 43.21  ? 476 HIS A N   1 
ATOM   3322  C CA  . HIS A 1 476 ? -24.710 2.073   -12.781 1.00 40.04  ? 476 HIS A CA  1 
ATOM   3323  C C   . HIS A 1 476 ? -24.716 0.529   -12.761 1.00 40.83  ? 476 HIS A C   1 
ATOM   3324  O O   . HIS A 1 476 ? -23.850 -0.117  -13.384 1.00 41.82  ? 476 HIS A O   1 
ATOM   3325  C CB  . HIS A 1 476 ? -24.540 2.633   -14.202 1.00 37.88  ? 476 HIS A CB  1 
ATOM   3326  C CG  . HIS A 1 476 ? -25.720 2.411   -15.074 1.00 37.86  ? 476 HIS A CG  1 
ATOM   3327  N ND1 . HIS A 1 476 ? -25.843 2.975   -16.315 1.00 43.88  ? 476 HIS A ND1 1 
ATOM   3328  C CD2 . HIS A 1 476 ? -26.831 1.664   -14.898 1.00 38.42  ? 476 HIS A CD2 1 
ATOM   3329  C CE1 . HIS A 1 476 ? -27.002 2.595   -16.851 1.00 42.13  ? 476 HIS A CE1 1 
ATOM   3330  N NE2 . HIS A 1 476 ? -27.612 1.810   -16.004 1.00 36.68  ? 476 HIS A NE2 1 
ATOM   3331  N N   . TRP A 1 477 ? -25.726 -0.054  -12.095 1.00 39.74  ? 477 TRP A N   1 
ATOM   3332  C CA  . TRP A 1 477 ? -25.929 -1.506  -12.091 1.00 37.87  ? 477 TRP A CA  1 
ATOM   3333  C C   . TRP A 1 477 ? -26.546 -1.947  -13.414 1.00 39.71  ? 477 TRP A C   1 
ATOM   3334  O O   . TRP A 1 477 ? -27.558 -1.424  -13.824 1.00 44.79  ? 477 TRP A O   1 
ATOM   3335  C CB  . TRP A 1 477 ? -26.839 -1.914  -10.937 1.00 40.64  ? 477 TRP A CB  1 
ATOM   3336  C CG  . TRP A 1 477 ? -26.259 -1.707  -9.566  1.00 46.25  ? 477 TRP A CG  1 
ATOM   3337  C CD1 . TRP A 1 477 ? -25.926 -0.519  -8.969  1.00 43.57  ? 477 TRP A CD1 1 
ATOM   3338  C CD2 . TRP A 1 477 ? -26.001 -2.740  -8.592  1.00 46.02  ? 477 TRP A CD2 1 
ATOM   3339  N NE1 . TRP A 1 477 ? -25.486 -0.743  -7.689  1.00 49.75  ? 477 TRP A NE1 1 
ATOM   3340  C CE2 . TRP A 1 477 ? -25.505 -2.096  -7.434  1.00 52.40  ? 477 TRP A CE2 1 
ATOM   3341  C CE3 . TRP A 1 477 ? -26.122 -4.135  -8.595  1.00 50.18  ? 477 TRP A CE3 1 
ATOM   3342  C CZ2 . TRP A 1 477 ? -25.130 -2.806  -6.295  1.00 55.33  ? 477 TRP A CZ2 1 
ATOM   3343  C CZ3 . TRP A 1 477 ? -25.753 -4.839  -7.462  1.00 54.01  ? 477 TRP A CZ3 1 
ATOM   3344  C CH2 . TRP A 1 477 ? -25.254 -4.182  -6.333  1.00 53.97  ? 477 TRP A CH2 1 
ATOM   3345  N N   . ILE A 1 478 ? -25.922 -2.910  -14.070 1.00 39.07  ? 478 ILE A N   1 
ATOM   3346  C CA  . ILE A 1 478 ? -26.454 -3.486  -15.286 1.00 35.18  ? 478 ILE A CA  1 
ATOM   3347  C C   . ILE A 1 478 ? -26.446 -4.996  -15.132 1.00 39.19  ? 478 ILE A C   1 
ATOM   3348  O O   . ILE A 1 478 ? -25.395 -5.587  -14.996 1.00 41.66  ? 478 ILE A O   1 
ATOM   3349  C CB  . ILE A 1 478 ? -25.646 -3.033  -16.514 1.00 39.18  ? 478 ILE A CB  1 
ATOM   3350  C CG1 . ILE A 1 478 ? -25.644 -1.532  -16.657 1.00 37.93  ? 478 ILE A CG1 1 
ATOM   3351  C CG2 . ILE A 1 478 ? -26.145 -3.720  -17.792 1.00 38.50  ? 478 ILE A CG2 1 
ATOM   3352  C CD1 . ILE A 1 478 ? -24.834 -1.024  -17.833 1.00 39.49  ? 478 ILE A CD1 1 
ATOM   3353  N N   . SER A 1 479 ? -27.648 -5.602  -15.163 1.00 42.56  ? 479 SER A N   1 
ATOM   3354  C CA  . SER A 1 479 ? -27.815 -7.037  -15.049 1.00 43.86  ? 479 SER A CA  1 
ATOM   3355  C C   . SER A 1 479 ? -27.947 -7.653  -16.439 1.00 45.71  ? 479 SER A C   1 
ATOM   3356  O O   . SER A 1 479 ? -28.714 -7.168  -17.250 1.00 55.18  ? 479 SER A O   1 
ATOM   3357  C CB  . SER A 1 479 ? -28.996 -7.360  -14.224 1.00 50.34  ? 479 SER A CB  1 
ATOM   3358  O OG  . SER A 1 479 ? -30.132 -7.635  -15.044 1.00 62.71  ? 479 SER A OG  1 
ATOM   3359  N N   . VAL A 1 480 ? -27.180 -8.720  -16.696 1.00 42.83  ? 480 VAL A N   1 
ATOM   3360  C CA  . VAL A 1 480 ? -27.148 -9.361  -18.001 1.00 45.80  ? 480 VAL A CA  1 
ATOM   3361  C C   . VAL A 1 480 ? -27.612 -10.800 -17.833 1.00 45.73  ? 480 VAL A C   1 
ATOM   3362  O O   . VAL A 1 480 ? -27.026 -11.559 -17.072 1.00 49.82  ? 480 VAL A O   1 
ATOM   3363  C CB  . VAL A 1 480 ? -25.752 -9.325  -18.671 1.00 53.46  ? 480 VAL A CB  1 
ATOM   3364  C CG1 . VAL A 1 480 ? -25.819 -9.714  -20.140 1.00 54.12  ? 480 VAL A CG1 1 
ATOM   3365  C CG2 . VAL A 1 480 ? -25.065 -7.967  -18.517 1.00 58.44  ? 480 VAL A CG2 1 
ATOM   3366  N N   . GLN A 1 481 ? -28.659 -11.163 -18.567 1.00 46.31  ? 481 GLN A N   1 
ATOM   3367  C CA  . GLN A 1 481 ? -29.162 -12.528 -18.589 1.00 51.54  ? 481 GLN A CA  1 
ATOM   3368  C C   . GLN A 1 481 ? -28.630 -13.249 -19.845 1.00 56.53  ? 481 GLN A C   1 
ATOM   3369  O O   . GLN A 1 481 ? -28.813 -12.776 -20.966 1.00 54.29  ? 481 GLN A O   1 
ATOM   3370  C CB  . GLN A 1 481 ? -30.687 -12.478 -18.572 1.00 51.09  ? 481 GLN A CB  1 
ATOM   3371  C CG  . GLN A 1 481 ? -31.340 -13.844 -18.584 1.00 52.38  ? 481 GLN A CG  1 
ATOM   3372  C CD  . GLN A 1 481 ? -31.057 -14.625 -17.328 1.00 53.31  ? 481 GLN A CD  1 
ATOM   3373  O OE1 . GLN A 1 481 ? -31.255 -14.135 -16.219 1.00 53.76  ? 481 GLN A OE1 1 
ATOM   3374  N NE2 . GLN A 1 481 ? -30.551 -15.836 -17.489 1.00 54.67  ? 481 GLN A NE2 1 
ATOM   3375  N N   . HIS A 1 482 ? -27.974 -14.400 -19.647 1.00 59.95  ? 482 HIS A N   1 
ATOM   3376  C CA  . HIS A 1 482 ? -27.336 -15.126 -20.752 1.00 61.54  ? 482 HIS A CA  1 
ATOM   3377  C C   . HIS A 1 482 ? -28.271 -16.230 -21.280 1.00 56.44  ? 482 HIS A C   1 
ATOM   3378  O O   . HIS A 1 482 ? -28.710 -17.062 -20.445 1.00 59.59  ? 482 HIS A O   1 
ATOM   3379  C CB  . HIS A 1 482 ? -25.972 -15.672 -20.316 1.00 60.34  ? 482 HIS A CB  1 
ATOM   3380  C CG  . HIS A 1 482 ? -24.967 -14.597 -19.991 1.00 58.27  ? 482 HIS A CG  1 
ATOM   3381  N ND1 . HIS A 1 482 ? -23.881 -14.303 -20.789 1.00 54.83  ? 482 HIS A ND1 1 
ATOM   3382  C CD2 . HIS A 1 482 ? -24.890 -13.765 -18.941 1.00 59.65  ? 482 HIS A CD2 1 
ATOM   3383  C CE1 . HIS A 1 482 ? -23.193 -13.315 -20.244 1.00 59.72  ? 482 HIS A CE1 1 
ATOM   3384  N NE2 . HIS A 1 482 ? -23.787 -12.970 -19.121 1.00 59.59  ? 482 HIS A NE2 1 
ATOM   3385  N N   . ASP B 1 3   ? 25.642  14.432  -15.854 1.00 132.01 ? 3   ASP B N   1 
ATOM   3386  C CA  . ASP B 1 3   ? 25.740  14.267  -17.302 1.00 114.89 ? 3   ASP B CA  1 
ATOM   3387  C C   . ASP B 1 3   ? 26.372  12.916  -17.623 1.00 103.81 ? 3   ASP B C   1 
ATOM   3388  O O   . ASP B 1 3   ? 25.972  12.247  -18.573 1.00 122.51 ? 3   ASP B O   1 
ATOM   3389  C CB  . ASP B 1 3   ? 26.576  15.362  -17.933 1.00 115.98 ? 3   ASP B CB  1 
ATOM   3390  C CG  . ASP B 1 3   ? 26.420  16.735  -17.318 1.00 127.27 ? 3   ASP B CG  1 
ATOM   3391  O OD1 . ASP B 1 3   ? 26.647  16.859  -16.095 1.00 123.38 ? 3   ASP B OD1 1 
ATOM   3392  O OD2 . ASP B 1 3   ? 26.090  17.663  -18.065 1.00 138.05 ? 3   ASP B OD2 1 
ATOM   3393  N N   . SER B 1 4   ? 27.398  12.554  -16.852 1.00 87.88  ? 4   SER B N   1 
ATOM   3394  C CA  . SER B 1 4   ? 28.196  11.380  -17.143 1.00 82.07  ? 4   SER B CA  1 
ATOM   3395  C C   . SER B 1 4   ? 27.412  10.141  -16.701 1.00 73.28  ? 4   SER B C   1 
ATOM   3396  O O   . SER B 1 4   ? 26.727  10.156  -15.676 1.00 66.10  ? 4   SER B O   1 
ATOM   3397  C CB  . SER B 1 4   ? 29.543  11.465  -16.475 1.00 85.06  ? 4   SER B CB  1 
ATOM   3398  O OG  . SER B 1 4   ? 30.241  10.236  -16.598 1.00 94.49  ? 4   SER B OG  1 
ATOM   3399  N N   . ARG B 1 5   ? 27.548  9.069   -17.475 1.00 65.95  ? 5   ARG B N   1 
ATOM   3400  C CA  . ARG B 1 5   ? 26.941  7.794   -17.145 1.00 58.77  ? 5   ARG B CA  1 
ATOM   3401  C C   . ARG B 1 5   ? 27.657  7.180   -15.933 1.00 52.26  ? 5   ARG B C   1 
ATOM   3402  O O   . ARG B 1 5   ? 28.788  7.526   -15.620 1.00 58.31  ? 5   ARG B O   1 
ATOM   3403  C CB  . ARG B 1 5   ? 26.993  6.839   -18.339 1.00 50.00  ? 5   ARG B CB  1 
ATOM   3404  C CG  . ARG B 1 5   ? 26.119  7.261   -19.509 1.00 50.00  ? 5   ARG B CG  1 
ATOM   3405  C CD  . ARG B 1 5   ? 26.133  6.289   -20.677 1.00 50.00  ? 5   ARG B CD  1 
ATOM   3406  N NE  . ARG B 1 5   ? 25.335  6.771   -21.801 1.00 50.00  ? 5   ARG B NE  1 
ATOM   3407  C CZ  . ARG B 1 5   ? 25.272  6.172   -22.981 1.00 50.00  ? 5   ARG B CZ  1 
ATOM   3408  N NH1 . ARG B 1 5   ? 25.959  5.058   -23.200 1.00 50.00  ? 5   ARG B NH1 1 
ATOM   3409  N NH2 . ARG B 1 5   ? 24.520  6.682   -23.948 1.00 50.00  ? 5   ARG B NH2 1 
ATOM   3410  N N   . TYR B 1 6   ? 26.986  6.253   -15.274 1.00 44.02  ? 6   TYR B N   1 
ATOM   3411  C CA  . TYR B 1 6   ? 27.569  5.542   -14.158 1.00 45.57  ? 6   TYR B CA  1 
ATOM   3412  C C   . TYR B 1 6   ? 28.860  4.818   -14.567 1.00 47.04  ? 6   TYR B C   1 
ATOM   3413  O O   . TYR B 1 6   ? 28.917  4.175   -15.629 1.00 42.27  ? 6   TYR B O   1 
ATOM   3414  C CB  . TYR B 1 6   ? 26.521  4.560   -13.602 1.00 45.19  ? 6   TYR B CB  1 
ATOM   3415  C CG  . TYR B 1 6   ? 25.249  5.188   -13.015 1.00 45.23  ? 6   TYR B CG  1 
ATOM   3416  C CD1 . TYR B 1 6   ? 25.298  6.348   -12.250 1.00 37.39  ? 6   TYR B CD1 1 
ATOM   3417  C CD2 . TYR B 1 6   ? 23.989  4.614   -13.238 1.00 45.79  ? 6   TYR B CD2 1 
ATOM   3418  C CE1 . TYR B 1 6   ? 24.149  6.904   -11.702 1.00 38.59  ? 6   TYR B CE1 1 
ATOM   3419  C CE2 . TYR B 1 6   ? 22.835  5.166   -12.693 1.00 42.53  ? 6   TYR B CE2 1 
ATOM   3420  C CZ  . TYR B 1 6   ? 22.920  6.312   -11.922 1.00 39.72  ? 6   TYR B CZ  1 
ATOM   3421  O OH  . TYR B 1 6   ? 21.807  6.868   -11.368 1.00 40.78  ? 6   TYR B OH  1 
ATOM   3422  N N   . THR B 1 7   ? 29.889  4.900   -13.698 1.00 48.30  ? 7   THR B N   1 
ATOM   3423  C CA  . THR B 1 7   ? 31.102  4.079   -13.843 1.00 49.27  ? 7   THR B CA  1 
ATOM   3424  C C   . THR B 1 7   ? 31.319  3.294   -12.548 1.00 45.24  ? 7   THR B C   1 
ATOM   3425  O O   . THR B 1 7   ? 30.582  3.457   -11.597 1.00 42.98  ? 7   THR B O   1 
ATOM   3426  C CB  . THR B 1 7   ? 32.314  4.968   -14.190 1.00 50.16  ? 7   THR B CB  1 
ATOM   3427  O OG1 . THR B 1 7   ? 32.527  5.850   -13.089 1.00 50.07  ? 7   THR B OG1 1 
ATOM   3428  C CG2 . THR B 1 7   ? 32.103  5.803   -15.444 1.00 47.91  ? 7   THR B CG2 1 
ATOM   3429  N N   . ASP B 1 8   ? 32.335  2.435   -12.533 1.00 47.68  ? 8   ASP B N   1 
ATOM   3430  C CA  . ASP B 1 8   ? 32.658  1.646   -11.359 1.00 44.25  ? 8   ASP B CA  1 
ATOM   3431  C C   . ASP B 1 8   ? 31.485  0.723   -11.008 1.00 41.12  ? 8   ASP B C   1 
ATOM   3432  O O   . ASP B 1 8   ? 31.204  0.520   -9.827  1.00 41.22  ? 8   ASP B O   1 
ATOM   3433  C CB  . ASP B 1 8   ? 33.031  2.541   -10.179 1.00 47.58  ? 8   ASP B CB  1 
ATOM   3434  C CG  . ASP B 1 8   ? 34.515  2.645   -9.849  1.00 49.59  ? 8   ASP B CG  1 
ATOM   3435  O OD1 . ASP B 1 8   ? 35.149  1.605   -9.726  1.00 52.36  ? 8   ASP B OD1 1 
ATOM   3436  O OD2 . ASP B 1 8   ? 34.993  3.775   -9.630  1.00 50.17  ? 8   ASP B OD2 1 
ATOM   3437  N N   . LEU B 1 9   ? 30.813  0.146   -12.041 1.00 41.37  ? 9   LEU B N   1 
ATOM   3438  C CA  . LEU B 1 9   ? 29.617  -0.682  -11.814 1.00 47.50  ? 9   LEU B CA  1 
ATOM   3439  C C   . LEU B 1 9   ? 30.010  -2.015  -11.156 1.00 47.57  ? 9   LEU B C   1 
ATOM   3440  O O   . LEU B 1 9   ? 29.148  -2.751  -10.686 1.00 60.10  ? 9   LEU B O   1 
ATOM   3441  C CB  . LEU B 1 9   ? 28.841  -0.936  -13.109 1.00 52.78  ? 9   LEU B CB  1 
ATOM   3442  C CG  . LEU B 1 9   ? 27.884  0.171   -13.593 1.00 55.82  ? 9   LEU B CG  1 
ATOM   3443  C CD1 . LEU B 1 9   ? 27.234  0.938   -12.454 1.00 55.55  ? 9   LEU B CD1 1 
ATOM   3444  C CD2 . LEU B 1 9   ? 28.589  1.110   -14.534 1.00 63.73  ? 9   LEU B CD2 1 
ATOM   3445  N N   . GLY B 1 10  ? 31.308  -2.312  -11.125 1.00 44.44  ? 10  GLY B N   1 
ATOM   3446  C CA  . GLY B 1 10  ? 31.796  -3.564  -10.579 1.00 42.84  ? 10  GLY B CA  1 
ATOM   3447  C C   . GLY B 1 10  ? 31.700  -3.616  -9.052  1.00 39.03  ? 10  GLY B C   1 
ATOM   3448  O O   . GLY B 1 10  ? 31.858  -4.685  -8.463  1.00 33.67  ? 10  GLY B O   1 
ATOM   3449  N N   . LEU B 1 11  ? 31.526  -2.447  -8.413  1.00 38.23  ? 11  LEU B N   1 
ATOM   3450  C CA  . LEU B 1 11  ? 31.394  -2.386  -6.960  1.00 40.32  ? 11  LEU B CA  1 
ATOM   3451  C C   . LEU B 1 11  ? 29.982  -2.845  -6.566  1.00 40.46  ? 11  LEU B C   1 
ATOM   3452  O O   . LEU B 1 11  ? 29.014  -2.546  -7.260  1.00 45.64  ? 11  LEU B O   1 
ATOM   3453  C CB  . LEU B 1 11  ? 31.672  -0.971  -6.474  1.00 40.92  ? 11  LEU B CB  1 
ATOM   3454  C CG  . LEU B 1 11  ? 33.090  -0.438  -6.682  1.00 42.83  ? 11  LEU B CG  1 
ATOM   3455  C CD1 . LEU B 1 11  ? 33.191  0.955   -6.076  1.00 47.22  ? 11  LEU B CD1 1 
ATOM   3456  C CD2 . LEU B 1 11  ? 34.139  -1.340  -6.106  1.00 41.87  ? 11  LEU B CD2 1 
ATOM   3457  N N   . GLN B 1 12  ? 29.887  -3.591  -5.455  1.00 35.65  ? 12  GLN B N   1 
ATOM   3458  C CA  . GLN B 1 12  ? 28.616  -4.104  -4.973  1.00 34.38  ? 12  GLN B CA  1 
ATOM   3459  C C   . GLN B 1 12  ? 28.096  -3.233  -3.840  1.00 34.83  ? 12  GLN B C   1 
ATOM   3460  O O   . GLN B 1 12  ? 28.850  -2.858  -2.944  1.00 30.86  ? 12  GLN B O   1 
ATOM   3461  C CB  . GLN B 1 12  ? 28.758  -5.541  -4.499  1.00 36.18  ? 12  GLN B CB  1 
ATOM   3462  C CG  . GLN B 1 12  ? 28.867  -6.547  -5.639  1.00 39.75  ? 12  GLN B CG  1 
ATOM   3463  C CD  . GLN B 1 12  ? 28.778  -7.978  -5.173  1.00 41.60  ? 12  GLN B CD  1 
ATOM   3464  O OE1 . GLN B 1 12  ? 27.732  -8.434  -4.691  1.00 43.16  ? 12  GLN B OE1 1 
ATOM   3465  N NE2 . GLN B 1 12  ? 29.877  -8.704  -5.316  1.00 38.37  ? 12  GLN B NE2 1 
ATOM   3466  N N   . PRO B 1 13  ? 26.786  -2.879  -3.849  1.00 38.13  ? 13  PRO B N   1 
ATOM   3467  C CA  . PRO B 1 13  ? 26.146  -2.258  -2.684  1.00 37.86  ? 13  PRO B CA  1 
ATOM   3468  C C   . PRO B 1 13  ? 25.880  -3.295  -1.585  1.00 34.44  ? 13  PRO B C   1 
ATOM   3469  O O   . PRO B 1 13  ? 24.954  -4.086  -1.687  1.00 31.38  ? 13  PRO B O   1 
ATOM   3470  C CB  . PRO B 1 13  ? 24.833  -1.668  -3.279  1.00 35.50  ? 13  PRO B CB  1 
ATOM   3471  C CG  . PRO B 1 13  ? 24.484  -2.621  -4.415  1.00 37.96  ? 13  PRO B CG  1 
ATOM   3472  C CD  . PRO B 1 13  ? 25.839  -3.132  -4.953  1.00 38.67  ? 13  PRO B CD  1 
ATOM   3473  N N   . LEU B 1 14  ? 26.734  -3.296  -0.571  1.00 34.44  ? 14  LEU B N   1 
ATOM   3474  C CA  . LEU B 1 14  ? 26.708  -4.297  0.484   1.00 37.17  ? 14  LEU B CA  1 
ATOM   3475  C C   . LEU B 1 14  ? 26.717  -3.585  1.828   1.00 36.40  ? 14  LEU B C   1 
ATOM   3476  O O   . LEU B 1 14  ? 27.678  -2.875  2.158   1.00 43.05  ? 14  LEU B O   1 
ATOM   3477  C CB  . LEU B 1 14  ? 27.911  -5.242  0.381   1.00 38.74  ? 14  LEU B CB  1 
ATOM   3478  C CG  . LEU B 1 14  ? 27.938  -6.201  -0.810  1.00 40.04  ? 14  LEU B CG  1 
ATOM   3479  C CD1 . LEU B 1 14  ? 29.249  -6.941  -0.826  1.00 42.57  ? 14  LEU B CD1 1 
ATOM   3480  C CD2 . LEU B 1 14  ? 26.787  -7.189  -0.781  1.00 40.56  ? 14  LEU B CD2 1 
ATOM   3481  N N   . ALA B 1 15  ? 25.654  -3.795  2.594   1.00 36.56  ? 15  ALA B N   1 
ATOM   3482  C CA  . ALA B 1 15  ? 25.558  -3.332  3.976   1.00 39.46  ? 15  ALA B CA  1 
ATOM   3483  C C   . ALA B 1 15  ? 25.896  -1.839  4.085   1.00 42.64  ? 15  ALA B C   1 
ATOM   3484  O O   . ALA B 1 15  ? 26.597  -1.443  5.008   1.00 43.21  ? 15  ALA B O   1 
ATOM   3485  C CB  . ALA B 1 15  ? 26.450  -4.165  4.855   1.00 34.72  ? 15  ALA B CB  1 
ATOM   3486  N N   . GLY B 1 16  ? 25.377  -1.022  3.127   1.00 45.42  ? 16  GLY B N   1 
ATOM   3487  C CA  . GLY B 1 16  ? 25.414  0.439   3.230   1.00 44.94  ? 16  GLY B CA  1 
ATOM   3488  C C   . GLY B 1 16  ? 26.702  1.045   2.647   1.00 46.09  ? 16  GLY B C   1 
ATOM   3489  O O   . GLY B 1 16  ? 26.947  2.236   2.806   1.00 45.67  ? 16  GLY B O   1 
ATOM   3490  N N   . GLU B 1 17  ? 27.515  0.225   1.964   1.00 45.25  ? 17  GLU B N   1 
ATOM   3491  C CA  . GLU B 1 17  ? 28.730  0.727   1.321   1.00 52.36  ? 17  GLU B CA  1 
ATOM   3492  C C   . GLU B 1 17  ? 28.874  0.103   -0.064  1.00 50.59  ? 17  GLU B C   1 
ATOM   3493  O O   . GLU B 1 17  ? 28.356  -0.977  -0.323  1.00 52.91  ? 17  GLU B O   1 
ATOM   3494  C CB  . GLU B 1 17  ? 29.981  0.446   2.166   1.00 58.02  ? 17  GLU B CB  1 
ATOM   3495  C CG  . GLU B 1 17  ? 30.234  -1.038  2.393   1.00 68.60  ? 17  GLU B CG  1 
ATOM   3496  C CD  . GLU B 1 17  ? 30.968  -1.340  3.676   1.00 82.12  ? 17  GLU B CD  1 
ATOM   3497  O OE1 . GLU B 1 17  ? 31.618  -0.403  4.219   1.00 74.04  ? 17  GLU B OE1 1 
ATOM   3498  O OE2 . GLU B 1 17  ? 30.840  -2.501  4.172   1.00 93.03  ? 17  GLU B OE2 1 
ATOM   3499  N N   . TRP B 1 18  ? 29.570  0.822   -0.953  1.00 44.50  ? 18  TRP B N   1 
ATOM   3500  C CA  . TRP B 1 18  ? 29.881  0.326   -2.271  1.00 41.46  ? 18  TRP B CA  1 
ATOM   3501  C C   . TRP B 1 18  ? 31.329  -0.196  -2.292  1.00 43.48  ? 18  TRP B C   1 
ATOM   3502  O O   . TRP B 1 18  ? 32.279  0.587   -2.180  1.00 38.92  ? 18  TRP B O   1 
ATOM   3503  C CB  . TRP B 1 18  ? 29.648  1.435   -3.303  1.00 41.56  ? 18  TRP B CB  1 
ATOM   3504  C CG  . TRP B 1 18  ? 28.186  1.785   -3.495  1.00 46.68  ? 18  TRP B CG  1 
ATOM   3505  C CD1 . TRP B 1 18  ? 27.433  2.642   -2.739  1.00 45.33  ? 18  TRP B CD1 1 
ATOM   3506  C CD2 . TRP B 1 18  ? 27.300  1.266   -4.510  1.00 42.99  ? 18  TRP B CD2 1 
ATOM   3507  N NE1 . TRP B 1 18  ? 26.153  2.700   -3.218  1.00 48.55  ? 18  TRP B NE1 1 
ATOM   3508  C CE2 . TRP B 1 18  ? 26.039  1.865   -4.299  1.00 46.00  ? 18  TRP B CE2 1 
ATOM   3509  C CE3 . TRP B 1 18  ? 27.448  0.366   -5.563  1.00 38.06  ? 18  TRP B CE3 1 
ATOM   3510  C CZ2 . TRP B 1 18  ? 24.943  1.583   -5.105  1.00 40.50  ? 18  TRP B CZ2 1 
ATOM   3511  C CZ3 . TRP B 1 18  ? 26.359  0.077   -6.348  1.00 35.87  ? 18  TRP B CZ3 1 
ATOM   3512  C CH2 . TRP B 1 18  ? 25.128  0.680   -6.125  1.00 37.13  ? 18  TRP B CH2 1 
ATOM   3513  N N   . ARG B 1 19  ? 31.483  -1.537  -2.382  1.00 36.86  ? 19  ARG B N   1 
ATOM   3514  C CA  . ARG B 1 19  ? 32.785  -2.166  -2.207  1.00 33.80  ? 19  ARG B CA  1 
ATOM   3515  C C   . ARG B 1 19  ? 32.845  -3.501  -2.950  1.00 33.82  ? 19  ARG B C   1 
ATOM   3516  O O   . ARG B 1 19  ? 31.865  -3.958  -3.508  1.00 37.13  ? 19  ARG B O   1 
ATOM   3517  C CB  . ARG B 1 19  ? 33.062  -2.393  -0.726  1.00 32.73  ? 19  ARG B CB  1 
ATOM   3518  C CG  . ARG B 1 19  ? 32.333  -3.581  -0.120  1.00 33.88  ? 19  ARG B CG  1 
ATOM   3519  C CD  . ARG B 1 19  ? 32.852  -3.905  1.244   1.00 33.64  ? 19  ARG B CD  1 
ATOM   3520  N NE  . ARG B 1 19  ? 31.928  -4.745  2.008   1.00 37.26  ? 19  ARG B NE  1 
ATOM   3521  C CZ  . ARG B 1 19  ? 31.786  -6.083  1.863   1.00 40.07  ? 19  ARG B CZ  1 
ATOM   3522  N NH1 . ARG B 1 19  ? 32.505  -6.771  0.947   1.00 40.28  ? 19  ARG B NH1 1 
ATOM   3523  N NH2 . ARG B 1 19  ? 30.917  -6.721  2.621   1.00 35.92  ? 19  ARG B NH2 1 
ATOM   3524  N N   . HIS B 1 20  ? 34.015  -4.129  -2.907  1.00 37.01  ? 20  HIS B N   1 
ATOM   3525  C CA  . HIS B 1 20  ? 34.240  -5.423  -3.542  1.00 36.68  ? 20  HIS B CA  1 
ATOM   3526  C C   . HIS B 1 20  ? 33.764  -6.556  -2.638  1.00 36.80  ? 20  HIS B C   1 
ATOM   3527  O O   . HIS B 1 20  ? 33.804  -6.450  -1.404  1.00 40.24  ? 20  HIS B O   1 
ATOM   3528  C CB  . HIS B 1 20  ? 35.726  -5.637  -3.841  1.00 35.88  ? 20  HIS B CB  1 
ATOM   3529  C CG  . HIS B 1 20  ? 36.260  -4.834  -4.967  1.00 34.32  ? 20  HIS B CG  1 
ATOM   3530  N ND1 . HIS B 1 20  ? 37.411  -4.081  -4.852  1.00 34.04  ? 20  HIS B ND1 1 
ATOM   3531  C CD2 . HIS B 1 20  ? 35.827  -4.670  -6.222  1.00 35.79  ? 20  HIS B CD2 1 
ATOM   3532  C CE1 . HIS B 1 20  ? 37.633  -3.448  -6.000  1.00 35.13  ? 20  HIS B CE1 1 
ATOM   3533  N NE2 . HIS B 1 20  ? 36.673  -3.775  -6.842  1.00 36.29  ? 20  HIS B NE2 1 
ATOM   3534  N N   . GLY B 1 21  ? 33.390  -7.665  -3.269  1.00 36.81  ? 21  GLY B N   1 
ATOM   3535  C CA  . GLY B 1 21  ? 33.081  -8.880  -2.556  1.00 41.96  ? 21  GLY B CA  1 
ATOM   3536  C C   . GLY B 1 21  ? 34.355  -9.597  -2.081  1.00 45.04  ? 21  GLY B C   1 
ATOM   3537  O O   . GLY B 1 21  ? 35.409  -9.490  -2.706  1.00 41.12  ? 21  GLY B O   1 
ATOM   3538  N N   . ARG B 1 22  ? 34.214  -10.386 -1.010  1.00 42.91  ? 22  ARG B N   1 
ATOM   3539  C CA  . ARG B 1 22  ? 35.337  -11.047 -0.381  1.00 41.19  ? 22  ARG B CA  1 
ATOM   3540  C C   . ARG B 1 22  ? 35.364  -12.548 -0.734  1.00 40.61  ? 22  ARG B C   1 
ATOM   3541  O O   . ARG B 1 22  ? 36.082  -13.305 -0.134  1.00 42.22  ? 22  ARG B O   1 
ATOM   3542  C CB  . ARG B 1 22  ? 35.258  -10.860 1.136   1.00 43.27  ? 22  ARG B CB  1 
ATOM   3543  C CG  . ARG B 1 22  ? 35.404  -9.412  1.585   1.00 49.04  ? 22  ARG B CG  1 
ATOM   3544  C CD  . ARG B 1 22  ? 35.583  -9.281  3.078   1.00 50.82  ? 22  ARG B CD  1 
ATOM   3545  N NE  . ARG B 1 22  ? 34.466  -9.914  3.792   1.00 71.40  ? 22  ARG B NE  1 
ATOM   3546  C CZ  . ARG B 1 22  ? 33.550  -9.266  4.512   1.00 76.45  ? 22  ARG B CZ  1 
ATOM   3547  N NH1 . ARG B 1 22  ? 33.668  -7.952  4.708   1.00 75.16  ? 22  ARG B NH1 1 
ATOM   3548  N NH2 . ARG B 1 22  ? 32.521  -9.936  5.032   1.00 72.57  ? 22  ARG B NH2 1 
ATOM   3549  N N   . ALA B 1 23  ? 34.607  -12.973 -1.716  1.00 43.45  ? 23  ALA B N   1 
ATOM   3550  C CA  . ALA B 1 23  ? 34.649  -14.385 -2.103  1.00 44.18  ? 23  ALA B CA  1 
ATOM   3551  C C   . ALA B 1 23  ? 36.022  -14.756 -2.697  1.00 47.16  ? 23  ALA B C   1 
ATOM   3552  O O   . ALA B 1 23  ? 36.393  -15.931 -2.709  1.00 52.82  ? 23  ALA B O   1 
ATOM   3553  C CB  . ALA B 1 23  ? 33.537  -14.693 -3.081  1.00 48.65  ? 23  ALA B CB  1 
ATOM   3554  N N   . GLY B 1 24  ? 36.701  -13.772 -3.304  1.00 45.76  ? 24  GLY B N   1 
ATOM   3555  C CA  . GLY B 1 24  ? 38.012  -13.981 -3.903  1.00 46.43  ? 24  GLY B CA  1 
ATOM   3556  C C   . GLY B 1 24  ? 37.942  -14.473 -5.364  1.00 44.92  ? 24  GLY B C   1 
ATOM   3557  O O   . GLY B 1 24  ? 38.957  -14.764 -5.945  1.00 41.67  ? 24  GLY B O   1 
ATOM   3558  N N   . ARG B 1 25  ? 36.737  -14.541 -5.941  1.00 48.22  ? 25  ARG B N   1 
ATOM   3559  C CA  . ARG B 1 25  ? 36.559  -14.999 -7.318  1.00 47.96  ? 25  ARG B CA  1 
ATOM   3560  C C   . ARG B 1 25  ? 35.889  -13.893 -8.136  1.00 49.00  ? 25  ARG B C   1 
ATOM   3561  O O   . ARG B 1 25  ? 35.125  -13.095 -7.599  1.00 51.68  ? 25  ARG B O   1 
ATOM   3562  C CB  . ARG B 1 25  ? 35.693  -16.264 -7.364  1.00 56.27  ? 25  ARG B CB  1 
ATOM   3563  C CG  . ARG B 1 25  ? 36.423  -17.586 -7.192  1.00 65.50  ? 25  ARG B CG  1 
ATOM   3564  C CD  . ARG B 1 25  ? 35.446  -18.770 -7.004  1.00 73.55  ? 25  ARG B CD  1 
ATOM   3565  N NE  . ARG B 1 25  ? 34.570  -18.632 -5.820  1.00 91.03  ? 25  ARG B NE  1 
ATOM   3566  C CZ  . ARG B 1 25  ? 34.971  -18.673 -4.518  1.00 93.06  ? 25  ARG B CZ  1 
ATOM   3567  N NH1 . ARG B 1 25  ? 34.077  -18.554 -3.544  1.00 89.29  ? 25  ARG B NH1 1 
ATOM   3568  N NH2 . ARG B 1 25  ? 36.251  -18.841 -4.209  1.00 87.75  ? 25  ARG B NH2 1 
ATOM   3569  N N   . ARG B 1 26  ? 36.158  -13.877 -9.443  1.00 43.36  ? 26  ARG B N   1 
ATOM   3570  C CA  . ARG B 1 26  ? 35.653  -12.833 -10.315 1.00 45.31  ? 26  ARG B CA  1 
ATOM   3571  C C   . ARG B 1 26  ? 34.617  -13.406 -11.245 1.00 46.78  ? 26  ARG B C   1 
ATOM   3572  O O   . ARG B 1 26  ? 34.806  -14.476 -11.791 1.00 68.00  ? 26  ARG B O   1 
ATOM   3573  C CB  . ARG B 1 26  ? 36.729  -12.229 -11.208 1.00 48.36  ? 26  ARG B CB  1 
ATOM   3574  C CG  . ARG B 1 26  ? 37.808  -11.457 -10.484 1.00 49.01  ? 26  ARG B CG  1 
ATOM   3575  C CD  . ARG B 1 26  ? 38.471  -10.409 -11.414 1.00 56.40  ? 26  ARG B CD  1 
ATOM   3576  N NE  . ARG B 1 26  ? 38.006  -9.056  -11.075 1.00 64.02  ? 26  ARG B NE  1 
ATOM   3577  C CZ  . ARG B 1 26  ? 38.312  -7.948  -11.702 1.00 60.93  ? 26  ARG B CZ  1 
ATOM   3578  N NH1 . ARG B 1 26  ? 39.010  -7.986  -12.836 1.00 59.26  ? 26  ARG B NH1 1 
ATOM   3579  N NH2 . ARG B 1 26  ? 37.879  -6.790  -11.214 1.00 59.37  ? 26  ARG B NH2 1 
ATOM   3580  N N   . LEU B 1 27  ? 33.559  -12.638 -11.478 1.00 48.37  ? 27  LEU B N   1 
ATOM   3581  C CA  . LEU B 1 27  ? 32.552  -12.982 -12.467 1.00 48.25  ? 27  LEU B CA  1 
ATOM   3582  C C   . LEU B 1 27  ? 32.758  -12.110 -13.694 1.00 44.33  ? 27  LEU B C   1 
ATOM   3583  O O   . LEU B 1 27  ? 32.881  -10.896 -13.576 1.00 41.36  ? 27  LEU B O   1 
ATOM   3584  C CB  . LEU B 1 27  ? 31.166  -12.773 -11.850 1.00 51.71  ? 27  LEU B CB  1 
ATOM   3585  C CG  . LEU B 1 27  ? 29.960  -12.892 -12.796 1.00 50.97  ? 27  LEU B CG  1 
ATOM   3586  C CD1 . LEU B 1 27  ? 29.808  -14.313 -13.340 1.00 46.99  ? 27  LEU B CD1 1 
ATOM   3587  C CD2 . LEU B 1 27  ? 28.687  -12.446 -12.085 1.00 46.74  ? 27  LEU B CD2 1 
ATOM   3588  N N   . LYS B 1 28  ? 32.801  -12.745 -14.862 1.00 45.96  ? 28  LYS B N   1 
ATOM   3589  C CA  . LYS B 1 28  ? 32.889  -12.035 -16.126 1.00 51.10  ? 28  LYS B CA  1 
ATOM   3590  C C   . LYS B 1 28  ? 31.489  -11.834 -16.665 1.00 45.99  ? 28  LYS B C   1 
ATOM   3591  O O   . LYS B 1 28  ? 30.700  -12.752 -16.669 1.00 43.11  ? 28  LYS B O   1 
ATOM   3592  C CB  . LYS B 1 28  ? 33.733  -12.814 -17.142 1.00 61.13  ? 28  LYS B CB  1 
ATOM   3593  C CG  . LYS B 1 28  ? 35.021  -13.375 -16.582 1.00 71.03  ? 28  LYS B CG  1 
ATOM   3594  C CD  . LYS B 1 28  ? 36.114  -13.583 -17.619 1.00 78.83  ? 28  LYS B CD  1 
ATOM   3595  C CE  . LYS B 1 28  ? 37.105  -14.630 -17.189 1.00 87.67  ? 28  LYS B CE  1 
ATOM   3596  N NZ  . LYS B 1 28  ? 36.482  -15.959 -17.082 1.00 85.80  ? 28  LYS B NZ  1 
ATOM   3597  N N   . VAL B 1 29  ? 31.202  -10.611 -17.098 1.00 46.70  ? 29  VAL B N   1 
ATOM   3598  C CA  . VAL B 1 29  ? 29.926  -10.278 -17.689 1.00 46.88  ? 29  VAL B CA  1 
ATOM   3599  C C   . VAL B 1 29  ? 30.187  -9.796  -19.113 1.00 52.08  ? 29  VAL B C   1 
ATOM   3600  O O   . VAL B 1 29  ? 30.924  -8.819  -19.337 1.00 43.01  ? 29  VAL B O   1 
ATOM   3601  C CB  . VAL B 1 29  ? 29.166  -9.205  -16.874 1.00 46.89  ? 29  VAL B CB  1 
ATOM   3602  C CG1 . VAL B 1 29  ? 27.683  -9.164  -17.231 1.00 46.51  ? 29  VAL B CG1 1 
ATOM   3603  C CG2 . VAL B 1 29  ? 29.357  -9.384  -15.374 1.00 45.99  ? 29  VAL B CG2 1 
ATOM   3604  N N   . SER B 1 30  ? 29.569  -10.479 -20.072 1.00 54.82  ? 30  SER B N   1 
ATOM   3605  C CA  . SER B 1 30  ? 29.922  -10.318 -21.469 1.00 56.35  ? 30  SER B CA  1 
ATOM   3606  C C   . SER B 1 30  ? 28.659  -10.175 -22.329 1.00 52.68  ? 30  SER B C   1 
ATOM   3607  O O   . SER B 1 30  ? 27.561  -10.536 -21.910 1.00 51.29  ? 30  SER B O   1 
ATOM   3608  C CB  . SER B 1 30  ? 30.795  -11.461 -21.933 1.00 54.11  ? 30  SER B CB  1 
ATOM   3609  O OG  . SER B 1 30  ? 30.236  -12.697 -21.549 1.00 55.67  ? 30  SER B OG  1 
ATOM   3610  N N   . ASN B 1 31  ? 28.849  -9.608  -23.519 1.00 49.80  ? 31  ASN B N   1 
ATOM   3611  C CA  . ASN B 1 31  ? 27.779  -9.370  -24.479 1.00 50.22  ? 31  ASN B CA  1 
ATOM   3612  C C   . ASN B 1 31  ? 27.432  -10.685 -25.195 1.00 52.67  ? 31  ASN B C   1 
ATOM   3613  O O   . ASN B 1 31  ? 28.305  -11.343 -25.715 1.00 51.73  ? 31  ASN B O   1 
ATOM   3614  C CB  . ASN B 1 31  ? 28.202  -8.312  -25.483 1.00 47.61  ? 31  ASN B CB  1 
ATOM   3615  C CG  . ASN B 1 31  ? 27.039  -7.667  -26.172 1.00 45.91  ? 31  ASN B CG  1 
ATOM   3616  O OD1 . ASN B 1 31  ? 26.076  -8.344  -26.535 1.00 50.24  ? 31  ASN B OD1 1 
ATOM   3617  N ND2 . ASN B 1 31  ? 27.108  -6.363  -26.363 1.00 44.40  ? 31  ASN B ND2 1 
ATOM   3618  N N   . PRO B 1 32  ? 26.153  -11.130 -25.202 1.00 55.39  ? 32  PRO B N   1 
ATOM   3619  C CA  . PRO B 1 32  ? 25.784  -12.358 -25.901 1.00 60.19  ? 32  PRO B CA  1 
ATOM   3620  C C   . PRO B 1 32  ? 26.009  -12.313 -27.418 1.00 63.79  ? 32  PRO B C   1 
ATOM   3621  O O   . PRO B 1 32  ? 26.191  -13.351 -28.041 1.00 61.70  ? 32  PRO B O   1 
ATOM   3622  C CB  . PRO B 1 32  ? 24.299  -12.529 -25.557 1.00 57.41  ? 32  PRO B CB  1 
ATOM   3623  C CG  . PRO B 1 32  ? 24.102  -11.690 -24.323 1.00 57.94  ? 32  PRO B CG  1 
ATOM   3624  C CD  . PRO B 1 32  ? 25.025  -10.528 -24.479 1.00 53.94  ? 32  PRO B CD  1 
ATOM   3625  N N   . PHE B 1 33  ? 25.963  -11.106 -28.004 1.00 60.03  ? 33  PHE B N   1 
ATOM   3626  C CA  . PHE B 1 33  ? 26.095  -10.951 -29.448 1.00 64.37  ? 33  PHE B CA  1 
ATOM   3627  C C   . PHE B 1 33  ? 27.539  -11.266 -29.871 1.00 67.21  ? 33  PHE B C   1 
ATOM   3628  O O   . PHE B 1 33  ? 27.786  -12.304 -30.450 1.00 73.42  ? 33  PHE B O   1 
ATOM   3629  C CB  . PHE B 1 33  ? 25.641  -9.557  -29.886 1.00 61.62  ? 33  PHE B CB  1 
ATOM   3630  C CG  . PHE B 1 33  ? 25.491  -9.405  -31.391 1.00 67.99  ? 33  PHE B CG  1 
ATOM   3631  C CD1 . PHE B 1 33  ? 24.553  -10.166 -32.094 1.00 72.66  ? 33  PHE B CD1 1 
ATOM   3632  C CD2 . PHE B 1 33  ? 26.279  -8.506  -32.108 1.00 60.45  ? 33  PHE B CD2 1 
ATOM   3633  C CE1 . PHE B 1 33  ? 24.419  -10.035 -33.474 1.00 65.42  ? 33  PHE B CE1 1 
ATOM   3634  C CE2 . PHE B 1 33  ? 26.133  -8.381  -33.485 1.00 55.48  ? 33  PHE B CE2 1 
ATOM   3635  C CZ  . PHE B 1 33  ? 25.208  -9.153  -34.161 1.00 56.64  ? 33  PHE B CZ  1 
ATOM   3636  N N   . ASP B 1 34  ? 28.484  -10.363 -29.557 1.00 72.58  ? 34  ASP B N   1 
ATOM   3637  C CA  . ASP B 1 34  ? 29.850  -10.450 -30.082 1.00 65.51  ? 34  ASP B CA  1 
ATOM   3638  C C   . ASP B 1 34  ? 30.774  -11.197 -29.110 1.00 64.25  ? 34  ASP B C   1 
ATOM   3639  O O   . ASP B 1 34  ? 31.870  -11.578 -29.488 1.00 79.31  ? 34  ASP B O   1 
ATOM   3640  C CB  . ASP B 1 34  ? 30.404  -9.077  -30.407 1.00 60.45  ? 34  ASP B CB  1 
ATOM   3641  C CG  . ASP B 1 34  ? 30.180  -8.023  -29.341 1.00 66.49  ? 34  ASP B CG  1 
ATOM   3642  O OD1 . ASP B 1 34  ? 29.970  -8.412  -28.163 1.00 70.14  ? 34  ASP B OD1 1 
ATOM   3643  O OD2 . ASP B 1 34  ? 30.147  -6.828  -29.701 1.00 58.82  ? 34  ASP B OD2 1 
ATOM   3644  N N   . GLY B 1 35  ? 30.344  -11.358 -27.847 1.00 66.39  ? 35  GLY B N   1 
ATOM   3645  C CA  . GLY B 1 35  ? 31.165  -12.014 -26.813 1.00 54.89  ? 35  GLY B CA  1 
ATOM   3646  C C   . GLY B 1 35  ? 32.139  -11.038 -26.113 1.00 53.84  ? 35  GLY B C   1 
ATOM   3647  O O   . GLY B 1 35  ? 33.009  -11.474 -25.344 1.00 51.84  ? 35  GLY B O   1 
ATOM   3648  N N   . SER B 1 36  ? 31.969  -9.715  -26.359 1.00 45.31  ? 36  SER B N   1 
ATOM   3649  C CA  . SER B 1 36  ? 32.841  -8.705  -25.764 1.00 46.16  ? 36  SER B CA  1 
ATOM   3650  C C   . SER B 1 36  ? 32.581  -8.587  -24.252 1.00 55.00  ? 36  SER B C   1 
ATOM   3651  O O   . SER B 1 36  ? 31.450  -8.711  -23.789 1.00 57.71  ? 36  SER B O   1 
ATOM   3652  C CB  . SER B 1 36  ? 32.681  -7.375  -26.445 1.00 48.31  ? 36  SER B CB  1 
ATOM   3653  O OG  . SER B 1 36  ? 31.343  -6.931  -26.383 1.00 57.44  ? 36  SER B OG  1 
ATOM   3654  N N   . LEU B 1 37  ? 33.640  -8.310  -23.497 1.00 53.13  ? 37  LEU B N   1 
ATOM   3655  C CA  . LEU B 1 37  ? 33.561  -8.283  -22.048 1.00 51.64  ? 37  LEU B CA  1 
ATOM   3656  C C   . LEU B 1 37  ? 33.017  -6.922  -21.570 1.00 56.43  ? 37  LEU B C   1 
ATOM   3657  O O   . LEU B 1 37  ? 33.587  -5.883  -21.880 1.00 59.47  ? 37  LEU B O   1 
ATOM   3658  C CB  . LEU B 1 37  ? 34.957  -8.559  -21.514 1.00 51.86  ? 37  LEU B CB  1 
ATOM   3659  C CG  . LEU B 1 37  ? 35.106  -8.511  -19.998 1.00 52.78  ? 37  LEU B CG  1 
ATOM   3660  C CD1 . LEU B 1 37  ? 34.368  -9.659  -19.357 1.00 58.69  ? 37  LEU B CD1 1 
ATOM   3661  C CD2 . LEU B 1 37  ? 36.560  -8.520  -19.610 1.00 55.66  ? 37  LEU B CD2 1 
ATOM   3662  N N   . LEU B 1 38  ? 31.912  -6.938  -20.796 1.00 51.32  ? 38  LEU B N   1 
ATOM   3663  C CA  . LEU B 1 38  ? 31.316  -5.695  -20.319 1.00 48.78  ? 38  LEU B CA  1 
ATOM   3664  C C   . LEU B 1 38  ? 32.017  -5.256  -19.036 1.00 47.02  ? 38  LEU B C   1 
ATOM   3665  O O   . LEU B 1 38  ? 32.338  -4.084  -18.885 1.00 43.18  ? 38  LEU B O   1 
ATOM   3666  C CB  . LEU B 1 38  ? 29.806  -5.797  -20.096 1.00 54.67  ? 38  LEU B CB  1 
ATOM   3667  C CG  . LEU B 1 38  ? 28.898  -5.605  -21.325 1.00 57.50  ? 38  LEU B CG  1 
ATOM   3668  C CD1 . LEU B 1 38  ? 29.533  -4.758  -22.459 1.00 50.60  ? 38  LEU B CD1 1 
ATOM   3669  C CD2 . LEU B 1 38  ? 28.449  -6.956  -21.841 1.00 59.93  ? 38  LEU B CD2 1 
ATOM   3670  N N   . LEU B 1 39  ? 32.121  -6.172  -18.058 1.00 46.32  ? 39  LEU B N   1 
ATOM   3671  C CA  . LEU B 1 39  ? 32.761  -5.852  -16.787 1.00 45.94  ? 39  LEU B CA  1 
ATOM   3672  C C   . LEU B 1 39  ? 33.067  -7.127  -16.047 1.00 43.56  ? 39  LEU B C   1 
ATOM   3673  O O   . LEU B 1 39  ? 32.654  -8.215  -16.454 1.00 43.64  ? 39  LEU B O   1 
ATOM   3674  C CB  . LEU B 1 39  ? 31.939  -4.895  -15.905 1.00 52.07  ? 39  LEU B CB  1 
ATOM   3675  C CG  . LEU B 1 39  ? 30.788  -5.507  -15.098 1.00 55.97  ? 39  LEU B CG  1 
ATOM   3676  C CD1 . LEU B 1 39  ? 30.363  -4.585  -13.962 1.00 60.10  ? 39  LEU B CD1 1 
ATOM   3677  C CD2 . LEU B 1 39  ? 29.602  -5.807  -15.983 1.00 63.59  ? 39  LEU B CD2 1 
ATOM   3678  N N   . GLU B 1 40  ? 33.849  -6.966  -14.977 1.00 43.60  ? 40  GLU B N   1 
ATOM   3679  C CA  . GLU B 1 40  ? 34.217  -8.049  -14.094 1.00 45.77  ? 40  GLU B CA  1 
ATOM   3680  C C   . GLU B 1 40  ? 33.856  -7.644  -12.665 1.00 43.39  ? 40  GLU B C   1 
ATOM   3681  O O   . GLU B 1 40  ? 34.105  -6.502  -12.255 1.00 45.35  ? 40  GLU B O   1 
ATOM   3682  C CB  . GLU B 1 40  ? 35.719  -8.356  -14.238 1.00 53.44  ? 40  GLU B CB  1 
ATOM   3683  C CG  . GLU B 1 40  ? 36.062  -9.438  -15.277 1.00 61.21  ? 40  GLU B CG  1 
ATOM   3684  C CD  . GLU B 1 40  ? 37.456  -10.059 -15.095 1.00 73.71  ? 40  GLU B CD  1 
ATOM   3685  O OE1 . GLU B 1 40  ? 38.433  -9.287  -15.074 1.00 79.14  ? 40  GLU B OE1 1 
ATOM   3686  O OE2 . GLU B 1 40  ? 37.562  -11.316 -14.943 1.00 81.40  ? 40  GLU B OE2 1 
ATOM   3687  N N   . ILE B 1 41  ? 33.278  -8.590  -11.910 1.00 38.65  ? 41  ILE B N   1 
ATOM   3688  C CA  . ILE B 1 41  ? 32.808  -8.319  -10.564 1.00 37.21  ? 41  ILE B CA  1 
ATOM   3689  C C   . ILE B 1 41  ? 33.469  -9.283  -9.599  1.00 37.30  ? 41  ILE B C   1 
ATOM   3690  O O   . ILE B 1 41  ? 33.340  -10.499 -9.756  1.00 39.93  ? 41  ILE B O   1 
ATOM   3691  C CB  . ILE B 1 41  ? 31.281  -8.436  -10.494 1.00 42.32  ? 41  ILE B CB  1 
ATOM   3692  C CG1 . ILE B 1 41  ? 30.617  -7.617  -11.579 1.00 46.19  ? 41  ILE B CG1 1 
ATOM   3693  C CG2 . ILE B 1 41  ? 30.765  -8.057  -9.107  1.00 42.44  ? 41  ILE B CG2 1 
ATOM   3694  C CD1 . ILE B 1 41  ? 29.133  -7.830  -11.676 1.00 47.95  ? 41  ILE B CD1 1 
ATOM   3695  N N   . GLU B 1 42  ? 34.124  -8.726  -8.566  1.00 34.65  ? 42  GLU B N   1 
ATOM   3696  C CA  . GLU B 1 42  ? 34.565  -9.498  -7.407  1.00 36.10  ? 42  GLU B CA  1 
ATOM   3697  C C   . GLU B 1 42  ? 33.338  -9.992  -6.628  1.00 35.79  ? 42  GLU B C   1 
ATOM   3698  O O   . GLU B 1 42  ? 32.635  -9.210  -6.013  1.00 40.40  ? 42  GLU B O   1 
ATOM   3699  C CB  . GLU B 1 42  ? 35.450  -8.650  -6.480  1.00 38.81  ? 42  GLU B CB  1 
ATOM   3700  C CG  . GLU B 1 42  ? 36.838  -8.360  -7.038  1.00 41.27  ? 42  GLU B CG  1 
ATOM   3701  C CD  . GLU B 1 42  ? 37.740  -9.594  -7.116  1.00 45.59  ? 42  GLU B CD  1 
ATOM   3702  O OE1 . GLU B 1 42  ? 37.627  -10.485 -6.232  1.00 47.24  ? 42  GLU B OE1 1 
ATOM   3703  O OE2 . GLU B 1 42  ? 38.569  -9.652  -8.040  1.00 42.56  ? 42  GLU B OE2 1 
ATOM   3704  N N   . GLN B 1 43  ? 33.138  -11.301 -6.633  1.00 38.35  ? 43  GLN B N   1 
ATOM   3705  C CA  . GLN B 1 43  ? 31.929  -11.904 -6.120  1.00 39.80  ? 43  GLN B CA  1 
ATOM   3706  C C   . GLN B 1 43  ? 31.876  -11.818 -4.590  1.00 42.01  ? 43  GLN B C   1 
ATOM   3707  O O   . GLN B 1 43  ? 32.914  -11.680 -3.908  1.00 39.04  ? 43  GLN B O   1 
ATOM   3708  C CB  . GLN B 1 43  ? 31.838  -13.355 -6.574  1.00 42.70  ? 43  GLN B CB  1 
ATOM   3709  C CG  . GLN B 1 43  ? 31.155  -13.529 -7.917  1.00 44.62  ? 43  GLN B CG  1 
ATOM   3710  C CD  . GLN B 1 43  ? 31.598  -14.774 -8.643  1.00 47.35  ? 43  GLN B CD  1 
ATOM   3711  O OE1 . GLN B 1 43  ? 32.760  -14.912 -9.035  1.00 67.15  ? 43  GLN B OE1 1 
ATOM   3712  N NE2 . GLN B 1 43  ? 30.674  -15.679 -8.859  1.00 51.99  ? 43  GLN B NE2 1 
ATOM   3713  N N   . ALA B 1 44  ? 30.645  -11.975 -4.067  1.00 41.34  ? 44  ALA B N   1 
ATOM   3714  C CA  . ALA B 1 44  ? 30.371  -11.902 -2.644  1.00 42.15  ? 44  ALA B CA  1 
ATOM   3715  C C   . ALA B 1 44  ? 30.330  -13.313 -2.033  1.00 39.89  ? 44  ALA B C   1 
ATOM   3716  O O   . ALA B 1 44  ? 29.932  -14.277 -2.680  1.00 38.32  ? 44  ALA B O   1 
ATOM   3717  C CB  . ALA B 1 44  ? 29.079  -11.175 -2.425  1.00 42.24  ? 44  ALA B CB  1 
ATOM   3718  N N   . ASP B 1 45  ? 30.767  -13.401 -0.784  1.00 42.73  ? 45  ASP B N   1 
ATOM   3719  C CA  . ASP B 1 45  ? 30.764  -14.641 -0.026  1.00 47.74  ? 45  ASP B CA  1 
ATOM   3720  C C   . ASP B 1 45  ? 29.596  -14.622 0.961   1.00 44.80  ? 45  ASP B C   1 
ATOM   3721  O O   . ASP B 1 45  ? 28.790  -13.697 0.973   1.00 47.62  ? 45  ASP B O   1 
ATOM   3722  C CB  . ASP B 1 45  ? 32.112  -14.848 0.674   1.00 45.19  ? 45  ASP B CB  1 
ATOM   3723  C CG  . ASP B 1 45  ? 32.449  -13.844 1.757   1.00 47.92  ? 45  ASP B CG  1 
ATOM   3724  O OD1 . ASP B 1 45  ? 31.546  -13.053 2.126   1.00 51.60  ? 45  ASP B OD1 1 
ATOM   3725  O OD2 . ASP B 1 45  ? 33.627  -13.837 2.212   1.00 55.54  ? 45  ASP B OD2 1 
ATOM   3726  N N   . ARG B 1 46  ? 29.569  -15.597 1.845   1.00 48.73  ? 46  ARG B N   1 
ATOM   3727  C CA  . ARG B 1 46  ? 28.476  -15.735 2.769   1.00 53.53  ? 46  ARG B CA  1 
ATOM   3728  C C   . ARG B 1 46  ? 28.595  -14.738 3.943   1.00 52.80  ? 46  ARG B C   1 
ATOM   3729  O O   . ARG B 1 46  ? 27.607  -14.446 4.578   1.00 58.92  ? 46  ARG B O   1 
ATOM   3730  C CB  . ARG B 1 46  ? 28.340  -17.200 3.224   1.00 68.67  ? 46  ARG B CB  1 
ATOM   3731  N N   . ASP B 1 47  ? 29.760  -14.168 4.204   1.00 52.83  ? 47  ASP B N   1 
ATOM   3732  C CA  . ASP B 1 47  ? 29.809  -13.083 5.191   1.00 48.09  ? 47  ASP B CA  1 
ATOM   3733  C C   . ASP B 1 47  ? 29.130  -11.841 4.629   1.00 44.58  ? 47  ASP B C   1 
ATOM   3734  O O   . ASP B 1 47  ? 28.397  -11.170 5.336   1.00 44.38  ? 47  ASP B O   1 
ATOM   3735  C CB  . ASP B 1 47  ? 31.205  -12.884 5.708   1.00 52.03  ? 47  ASP B CB  1 
ATOM   3736  C CG  . ASP B 1 47  ? 31.800  -14.148 6.264   1.00 59.01  ? 47  ASP B CG  1 
ATOM   3737  O OD1 . ASP B 1 47  ? 33.023  -14.340 6.098   1.00 63.41  ? 47  ASP B OD1 1 
ATOM   3738  O OD2 . ASP B 1 47  ? 30.994  -15.000 6.731   1.00 61.84  ? 47  ASP B OD2 1 
ATOM   3739  N N   . ASP B 1 48  ? 29.314  -11.608 3.334   1.00 44.32  ? 48  ASP B N   1 
ATOM   3740  C CA  . ASP B 1 48  ? 28.725  -10.470 2.650   1.00 45.70  ? 48  ASP B CA  1 
ATOM   3741  C C   . ASP B 1 48  ? 27.186  -10.543 2.719   1.00 45.07  ? 48  ASP B C   1 
ATOM   3742  O O   . ASP B 1 48  ? 26.514  -9.521  2.945   1.00 39.24  ? 48  ASP B O   1 
ATOM   3743  C CB  . ASP B 1 48  ? 29.239  -10.377 1.217   1.00 44.39  ? 48  ASP B CB  1 
ATOM   3744  C CG  . ASP B 1 48  ? 30.730  -10.090 1.079   1.00 44.15  ? 48  ASP B CG  1 
ATOM   3745  O OD1 . ASP B 1 48  ? 31.254  -9.317  1.908   1.00 48.38  ? 48  ASP B OD1 1 
ATOM   3746  O OD2 . ASP B 1 48  ? 31.353  -10.628 0.143   1.00 37.84  ? 48  ASP B OD2 1 
ATOM   3747  N N   . LEU B 1 49  ? 26.630  -11.734 2.488   1.00 39.50  ? 49  LEU B N   1 
ATOM   3748  C CA  . LEU B 1 49  ? 25.180  -11.901 2.496   1.00 42.95  ? 49  LEU B CA  1 
ATOM   3749  C C   . LEU B 1 49  ? 24.623  -11.606 3.905   1.00 40.42  ? 49  LEU B C   1 
ATOM   3750  O O   . LEU B 1 49  ? 23.672  -10.862 4.047   1.00 42.23  ? 49  LEU B O   1 
ATOM   3751  C CB  . LEU B 1 49  ? 24.835  -13.309 2.023   1.00 45.10  ? 49  LEU B CB  1 
ATOM   3752  C CG  . LEU B 1 49  ? 23.366  -13.693 2.065   1.00 46.86  ? 49  LEU B CG  1 
ATOM   3753  C CD1 . LEU B 1 49  ? 22.559  -12.784 1.166   1.00 48.87  ? 49  LEU B CD1 1 
ATOM   3754  C CD2 . LEU B 1 49  ? 23.205  -15.145 1.664   1.00 49.09  ? 49  LEU B CD2 1 
ATOM   3755  N N   . ASP B 1 50  ? 25.252  -12.177 4.935   1.00 41.81  ? 50  ASP B N   1 
ATOM   3756  C CA  . ASP B 1 50  ? 24.822  -11.987 6.311   1.00 39.58  ? 50  ASP B CA  1 
ATOM   3757  C C   . ASP B 1 50  ? 24.864  -10.510 6.676   1.00 35.85  ? 50  ASP B C   1 
ATOM   3758  O O   . ASP B 1 50  ? 23.960  -10.005 7.320   1.00 37.11  ? 50  ASP B O   1 
ATOM   3759  C CB  . ASP B 1 50  ? 25.677  -12.800 7.269   1.00 46.80  ? 50  ASP B CB  1 
ATOM   3760  C CG  . ASP B 1 50  ? 25.463  -14.303 7.206   1.00 53.32  ? 50  ASP B CG  1 
ATOM   3761  O OD1 . ASP B 1 50  ? 24.468  -14.726 6.580   1.00 56.54  ? 50  ASP B OD1 1 
ATOM   3762  O OD2 . ASP B 1 50  ? 26.315  -15.038 7.742   1.00 60.39  ? 50  ASP B OD2 1 
ATOM   3763  N N   . ALA B 1 51  ? 25.944  -9.839  6.299   1.00 35.62  ? 51  ALA B N   1 
ATOM   3764  C CA  . ALA B 1 51  ? 26.093  -8.420  6.571   1.00 35.36  ? 51  ALA B CA  1 
ATOM   3765  C C   . ALA B 1 51  ? 25.003  -7.624  5.858   1.00 36.33  ? 51  ALA B C   1 
ATOM   3766  O O   . ALA B 1 51  ? 24.473  -6.681  6.427   1.00 38.15  ? 51  ALA B O   1 
ATOM   3767  C CB  . ALA B 1 51  ? 27.465  -7.957  6.163   1.00 33.83  ? 51  ALA B CB  1 
ATOM   3768  N N   . ALA B 1 52  ? 24.682  -8.012  4.603   1.00 36.23  ? 52  ALA B N   1 
ATOM   3769  C CA  . ALA B 1 52  ? 23.703  -7.278  3.793   1.00 37.72  ? 52  ALA B CA  1 
ATOM   3770  C C   . ALA B 1 52  ? 22.313  -7.390  4.414   1.00 37.79  ? 52  ALA B C   1 
ATOM   3771  O O   . ALA B 1 52  ? 21.604  -6.397  4.542   1.00 33.78  ? 52  ALA B O   1 
ATOM   3772  C CB  . ALA B 1 52  ? 23.705  -7.792  2.371   1.00 35.93  ? 52  ALA B CB  1 
ATOM   3773  N N   . TYR B 1 53  ? 21.945  -8.607  4.819   1.00 38.50  ? 53  TYR B N   1 
ATOM   3774  C CA  . TYR B 1 53  ? 20.656  -8.847  5.464   1.00 38.26  ? 53  TYR B CA  1 
ATOM   3775  C C   . TYR B 1 53  ? 20.592  -8.093  6.807   1.00 41.95  ? 53  TYR B C   1 
ATOM   3776  O O   . TYR B 1 53  ? 19.587  -7.453  7.101   1.00 41.60  ? 53  TYR B O   1 
ATOM   3777  C CB  . TYR B 1 53  ? 20.428  -10.351 5.655   1.00 38.65  ? 53  TYR B CB  1 
ATOM   3778  C CG  . TYR B 1 53  ? 19.691  -11.036 4.514   1.00 39.83  ? 53  TYR B CG  1 
ATOM   3779  C CD1 . TYR B 1 53  ? 18.556  -10.458 3.936   1.00 41.67  ? 53  TYR B CD1 1 
ATOM   3780  C CD2 . TYR B 1 53  ? 20.112  -12.260 4.019   1.00 37.79  ? 53  TYR B CD2 1 
ATOM   3781  C CE1 . TYR B 1 53  ? 17.873  -11.078 2.899   1.00 37.14  ? 53  TYR B CE1 1 
ATOM   3782  C CE2 . TYR B 1 53  ? 19.420  -12.905 2.995   1.00 37.24  ? 53  TYR B CE2 1 
ATOM   3783  C CZ  . TYR B 1 53  ? 18.288  -12.315 2.447   1.00 36.84  ? 53  TYR B CZ  1 
ATOM   3784  O OH  . TYR B 1 53  ? 17.617  -12.920 1.419   1.00 34.41  ? 53  TYR B OH  1 
ATOM   3785  N N   . ALA B 1 54  ? 21.673  -8.194  7.622   1.00 38.59  ? 54  ALA B N   1 
ATOM   3786  C CA  . ALA B 1 54  ? 21.711  -7.594  8.958   1.00 33.96  ? 54  ALA B CA  1 
ATOM   3787  C C   . ALA B 1 54  ? 21.540  -6.097  8.858   1.00 33.68  ? 54  ALA B C   1 
ATOM   3788  O O   . ALA B 1 54  ? 20.773  -5.511  9.605   1.00 39.17  ? 54  ALA B O   1 
ATOM   3789  C CB  . ALA B 1 54  ? 23.013  -7.942  9.675   1.00 33.02  ? 54  ALA B CB  1 
ATOM   3790  N N   . LYS B 1 55  ? 22.269  -5.482  7.932   1.00 36.16  ? 55  LYS B N   1 
ATOM   3791  C CA  . LYS B 1 55  ? 22.232  -4.040  7.774   1.00 33.66  ? 55  LYS B CA  1 
ATOM   3792  C C   . LYS B 1 55  ? 20.821  -3.608  7.375   1.00 34.12  ? 55  LYS B C   1 
ATOM   3793  O O   . LYS B 1 55  ? 20.304  -2.625  7.902   1.00 34.18  ? 55  LYS B O   1 
ATOM   3794  C CB  . LYS B 1 55  ? 23.260  -3.564  6.751   1.00 34.68  ? 55  LYS B CB  1 
ATOM   3795  C CG  . LYS B 1 55  ? 23.447  -2.056  6.721   1.00 42.70  ? 55  LYS B CG  1 
ATOM   3796  C CD  . LYS B 1 55  ? 23.584  -1.454  8.115   1.00 50.91  ? 55  LYS B CD  1 
ATOM   3797  C CE  . LYS B 1 55  ? 24.370  -0.196  8.141   1.00 57.92  ? 55  LYS B CE  1 
ATOM   3798  N NZ  . LYS B 1 55  ? 25.219  -0.182  9.334   1.00 61.39  ? 55  LYS B NZ  1 
ATOM   3799  N N   . ALA B 1 56  ? 20.206  -4.357  6.435   1.00 33.32  ? 56  ALA B N   1 
ATOM   3800  C CA  . ALA B 1 56  ? 18.860  -4.043  5.963   1.00 37.86  ? 56  ALA B CA  1 
ATOM   3801  C C   . ALA B 1 56  ? 17.874  -4.072  7.128   1.00 37.08  ? 56  ALA B C   1 
ATOM   3802  O O   . ALA B 1 56  ? 17.045  -3.185  7.249   1.00 41.82  ? 56  ALA B O   1 
ATOM   3803  C CB  . ALA B 1 56  ? 18.437  -5.003  4.850   1.00 37.53  ? 56  ALA B CB  1 
ATOM   3804  N N   . ALA B 1 57  ? 17.991  -5.087  7.994   1.00 38.56  ? 57  ALA B N   1 
ATOM   3805  C CA  . ALA B 1 57  ? 17.096  -5.218  9.143   1.00 41.72  ? 57  ALA B CA  1 
ATOM   3806  C C   . ALA B 1 57  ? 17.295  -4.053  10.117  1.00 43.89  ? 57  ALA B C   1 
ATOM   3807  O O   . ALA B 1 57  ? 16.347  -3.591  10.721  1.00 43.18  ? 57  ALA B O   1 
ATOM   3808  C CB  . ALA B 1 57  ? 17.305  -6.541  9.831   1.00 39.97  ? 57  ALA B CB  1 
ATOM   3809  N N   . GLU B 1 58  ? 18.528  -3.574  10.238  1.00 45.01  ? 58  GLU B N   1 
ATOM   3810  C CA  . GLU B 1 58  ? 18.856  -2.546  11.217  1.00 49.20  ? 58  GLU B CA  1 
ATOM   3811  C C   . GLU B 1 58  ? 18.264  -1.190  10.797  1.00 43.44  ? 58  GLU B C   1 
ATOM   3812  O O   . GLU B 1 58  ? 17.713  -0.491  11.625  1.00 42.22  ? 58  GLU B O   1 
ATOM   3813  C CB  . GLU B 1 58  ? 20.372  -2.507  11.425  1.00 53.77  ? 58  GLU B CB  1 
ATOM   3814  C CG  . GLU B 1 58  ? 20.865  -1.273  12.180  1.00 57.62  ? 58  GLU B CG  1 
ATOM   3815  C CD  . GLU B 1 58  ? 22.315  -0.909  11.842  1.00 66.41  ? 58  GLU B CD  1 
ATOM   3816  O OE1 . GLU B 1 58  ? 23.190  -1.800  11.980  1.00 63.90  ? 58  GLU B OE1 1 
ATOM   3817  O OE2 . GLU B 1 58  ? 22.568  0.253   11.398  1.00 67.04  ? 58  GLU B OE2 1 
ATOM   3818  N N   . VAL B 1 59  ? 18.395  -0.824  9.511   1.00 45.29  ? 59  VAL B N   1 
ATOM   3819  C CA  . VAL B 1 59  ? 18.081  0.543   9.061   1.00 42.22  ? 59  VAL B CA  1 
ATOM   3820  C C   . VAL B 1 59  ? 16.620  0.632   8.610   1.00 38.12  ? 59  VAL B C   1 
ATOM   3821  O O   . VAL B 1 59  ? 16.095  1.729   8.453   1.00 35.28  ? 59  VAL B O   1 
ATOM   3822  C CB  . VAL B 1 59  ? 19.019  1.057   7.946   1.00 44.48  ? 59  VAL B CB  1 
ATOM   3823  C CG1 . VAL B 1 59  ? 20.447  1.203   8.440   1.00 45.99  ? 59  VAL B CG1 1 
ATOM   3824  C CG2 . VAL B 1 59  ? 18.972  0.189   6.684   1.00 42.59  ? 59  VAL B CG2 1 
ATOM   3825  N N   . GLN B 1 60  ? 15.974  -0.520  8.390   1.00 38.07  ? 60  GLN B N   1 
ATOM   3826  C CA  . GLN B 1 60  ? 14.606  -0.552  7.849   1.00 38.23  ? 60  GLN B CA  1 
ATOM   3827  C C   . GLN B 1 60  ? 13.616  0.228   8.756   1.00 43.09  ? 60  GLN B C   1 
ATOM   3828  O O   . GLN B 1 60  ? 12.741  0.933   8.228   1.00 40.17  ? 60  GLN B O   1 
ATOM   3829  C CB  . GLN B 1 60  ? 14.135  -1.993  7.632   1.00 35.44  ? 60  GLN B CB  1 
ATOM   3830  C CG  . GLN B 1 60  ? 12.708  -2.107  7.105   1.00 36.85  ? 60  GLN B CG  1 
ATOM   3831  C CD  . GLN B 1 60  ? 11.653  -2.249  8.192   1.00 39.33  ? 60  GLN B CD  1 
ATOM   3832  O OE1 . GLN B 1 60  ? 11.939  -2.656  9.327   1.00 40.75  ? 60  GLN B OE1 1 
ATOM   3833  N NE2 . GLN B 1 60  ? 10.411  -1.951  7.839   1.00 35.29  ? 60  GLN B NE2 1 
ATOM   3834  N N   . PRO B 1 61  ? 13.649  0.070   10.129  1.00 41.58  ? 61  PRO B N   1 
ATOM   3835  C CA  . PRO B 1 61  ? 12.712  0.787   11.018  1.00 39.66  ? 61  PRO B CA  1 
ATOM   3836  C C   . PRO B 1 61  ? 12.664  2.288   10.810  1.00 39.53  ? 61  PRO B C   1 
ATOM   3837  O O   . PRO B 1 61  ? 11.596  2.875   10.809  1.00 48.33  ? 61  PRO B O   1 
ATOM   3838  C CB  . PRO B 1 61  ? 13.215  0.414   12.420  1.00 40.28  ? 61  PRO B CB  1 
ATOM   3839  C CG  . PRO B 1 61  ? 13.739  -1.007  12.237  1.00 42.25  ? 61  PRO B CG  1 
ATOM   3840  C CD  . PRO B 1 61  ? 14.445  -0.929  10.866  1.00 44.94  ? 61  PRO B CD  1 
ATOM   3841  N N   . ALA B 1 62  ? 13.816  2.895   10.592  1.00 38.14  ? 62  ALA B N   1 
ATOM   3842  C CA  . ALA B 1 62  ? 13.881  4.333   10.370  1.00 38.34  ? 62  ALA B CA  1 
ATOM   3843  C C   . ALA B 1 62  ? 13.178  4.692   9.067   1.00 40.21  ? 62  ALA B C   1 
ATOM   3844  O O   . ALA B 1 62  ? 12.565  5.751   8.960   1.00 49.18  ? 62  ALA B O   1 
ATOM   3845  C CB  . ALA B 1 62  ? 15.332  4.789   10.370  1.00 38.99  ? 62  ALA B CB  1 
ATOM   3846  N N   . TRP B 1 63  ? 13.302  3.810   8.070   1.00 40.01  ? 63  TRP B N   1 
ATOM   3847  C CA  . TRP B 1 63  ? 12.702  4.023   6.761   1.00 40.39  ? 63  TRP B CA  1 
ATOM   3848  C C   . TRP B 1 63  ? 11.187  4.000   6.892   1.00 38.02  ? 63  TRP B C   1 
ATOM   3849  O O   . TRP B 1 63  ? 10.510  4.903   6.401   1.00 33.43  ? 63  TRP B O   1 
ATOM   3850  C CB  . TRP B 1 63  ? 13.205  2.946   5.775   1.00 37.39  ? 63  TRP B CB  1 
ATOM   3851  C CG  . TRP B 1 63  ? 12.636  3.023   4.390   1.00 34.76  ? 63  TRP B CG  1 
ATOM   3852  C CD1 . TRP B 1 63  ? 12.029  1.999   3.702   1.00 35.75  ? 63  TRP B CD1 1 
ATOM   3853  C CD2 . TRP B 1 63  ? 12.703  4.146   3.477   1.00 36.04  ? 63  TRP B CD2 1 
ATOM   3854  N NE1 . TRP B 1 63  ? 11.684  2.416   2.440   1.00 36.44  ? 63  TRP B NE1 1 
ATOM   3855  C CE2 . TRP B 1 63  ? 12.093  3.729   2.270   1.00 35.45  ? 63  TRP B CE2 1 
ATOM   3856  C CE3 . TRP B 1 63  ? 13.217  5.443   3.555   1.00 37.63  ? 63  TRP B CE3 1 
ATOM   3857  C CZ2 . TRP B 1 63  ? 11.978  4.572   1.171   1.00 34.58  ? 63  TRP B CZ2 1 
ATOM   3858  C CZ3 . TRP B 1 63  ? 13.112  6.272   2.457   1.00 38.02  ? 63  TRP B CZ3 1 
ATOM   3859  C CH2 . TRP B 1 63  ? 12.494  5.844   1.288   1.00 36.47  ? 63  TRP B CH2 1 
ATOM   3860  N N   . ALA B 1 64  ? 10.673  2.961   7.582   1.00 39.17  ? 64  ALA B N   1 
ATOM   3861  C CA  . ALA B 1 64  ? 9.236   2.801   7.800   1.00 41.92  ? 64  ALA B CA  1 
ATOM   3862  C C   . ALA B 1 64  ? 8.694   3.980   8.609   1.00 44.84  ? 64  ALA B C   1 
ATOM   3863  O O   . ALA B 1 64  ? 7.574   4.409   8.380   1.00 47.83  ? 64  ALA B O   1 
ATOM   3864  C CB  . ALA B 1 64  ? 8.940   1.479   8.490   1.00 38.70  ? 64  ALA B CB  1 
ATOM   3865  N N   . ALA B 1 65  ? 9.517   4.515   9.527   1.00 43.64  ? 65  ALA B N   1 
ATOM   3866  C CA  . ALA B 1 65  ? 9.079   5.565   10.444  1.00 50.87  ? 65  ALA B CA  1 
ATOM   3867  C C   . ALA B 1 65  ? 8.889   6.894   9.712   1.00 53.95  ? 65  ALA B C   1 
ATOM   3868  O O   . ALA B 1 65  ? 8.199   7.760   10.213  1.00 56.34  ? 65  ALA B O   1 
ATOM   3869  C CB  . ALA B 1 65  ? 10.066  5.716   11.593  1.00 50.14  ? 65  ALA B CB  1 
ATOM   3870  N N   . LEU B 1 66  ? 9.553   7.067   8.558   1.00 55.26  ? 66  LEU B N   1 
ATOM   3871  C CA  . LEU B 1 66  ? 9.340   8.253   7.736   1.00 54.99  ? 66  LEU B CA  1 
ATOM   3872  C C   . LEU B 1 66  ? 7.877   8.309   7.315   1.00 58.56  ? 66  LEU B C   1 
ATOM   3873  O O   . LEU B 1 66  ? 7.196   7.297   7.247   1.00 69.59  ? 66  LEU B O   1 
ATOM   3874  C CB  . LEU B 1 66  ? 10.236  8.266   6.501   1.00 55.45  ? 66  LEU B CB  1 
ATOM   3875  C CG  . LEU B 1 66  ? 11.721  8.556   6.719   1.00 57.29  ? 66  LEU B CG  1 
ATOM   3876  C CD1 . LEU B 1 66  ? 12.342  9.011   5.395   1.00 59.72  ? 66  LEU B CD1 1 
ATOM   3877  C CD2 . LEU B 1 66  ? 11.965  9.570   7.802   1.00 56.60  ? 66  LEU B CD2 1 
ATOM   3878  N N   . GLY B 1 67  ? 7.420   9.495   6.985   1.00 65.19  ? 67  GLY B N   1 
ATOM   3879  C CA  . GLY B 1 67  ? 6.075   9.659   6.496   1.00 59.01  ? 67  GLY B CA  1 
ATOM   3880  C C   . GLY B 1 67  ? 5.924   9.012   5.131   1.00 56.94  ? 67  GLY B C   1 
ATOM   3881  O O   . GLY B 1 67  ? 6.907   8.773   4.433   1.00 58.14  ? 67  GLY B O   1 
ATOM   3882  N N   . PRO B 1 68  ? 4.694   8.738   4.694   1.00 52.08  ? 68  PRO B N   1 
ATOM   3883  C CA  . PRO B 1 68  ? 4.462   8.306   3.332   1.00 49.61  ? 68  PRO B CA  1 
ATOM   3884  C C   . PRO B 1 68  ? 5.010   9.285   2.299   1.00 47.73  ? 68  PRO B C   1 
ATOM   3885  O O   . PRO B 1 68  ? 5.514   8.862   1.270   1.00 53.05  ? 68  PRO B O   1 
ATOM   3886  C CB  . PRO B 1 68  ? 2.922   8.129   3.238   1.00 46.63  ? 68  PRO B CB  1 
ATOM   3887  C CG  . PRO B 1 68  ? 2.385   8.862   4.443   1.00 53.25  ? 68  PRO B CG  1 
ATOM   3888  C CD  . PRO B 1 68  ? 3.474   8.776   5.498   1.00 52.68  ? 68  PRO B CD  1 
ATOM   3889  N N   . SER B 1 69  ? 4.939   10.590  2.592   1.00 44.94  ? 69  SER B N   1 
ATOM   3890  C CA  . SER B 1 69  ? 5.393   11.611  1.635   1.00 44.27  ? 69  SER B CA  1 
ATOM   3891  C C   . SER B 1 69  ? 6.909   11.522  1.402   1.00 41.78  ? 69  SER B C   1 
ATOM   3892  O O   . SER B 1 69  ? 7.377   11.673  0.274   1.00 44.27  ? 69  SER B O   1 
ATOM   3893  C CB  . SER B 1 69  ? 5.012   12.986  2.069   1.00 44.77  ? 69  SER B CB  1 
ATOM   3894  O OG  . SER B 1 69  ? 3.651   13.246  1.770   1.00 49.15  ? 69  SER B OG  1 
ATOM   3895  N N   . ALA B 1 70  ? 7.670   11.307  2.468   1.00 41.32  ? 70  ALA B N   1 
ATOM   3896  C CA  . ALA B 1 70  ? 9.119   11.227  2.344   1.00 39.74  ? 70  ALA B CA  1 
ATOM   3897  C C   . ALA B 1 70  ? 9.508   10.024  1.469   1.00 42.03  ? 70  ALA B C   1 
ATOM   3898  O O   . ALA B 1 70  ? 10.336  10.154  0.566   1.00 46.38  ? 70  ALA B O   1 
ATOM   3899  C CB  . ALA B 1 70  ? 9.752   11.151  3.704   1.00 39.00  ? 70  ALA B CB  1 
ATOM   3900  N N   . ARG B 1 71  ? 8.898   8.855   1.740   1.00 35.81  ? 71  ARG B N   1 
ATOM   3901  C CA  . ARG B 1 71  ? 9.196   7.657   0.978   1.00 35.05  ? 71  ARG B CA  1 
ATOM   3902  C C   . ARG B 1 71  ? 8.754   7.850   -0.474  1.00 38.57  ? 71  ARG B C   1 
ATOM   3903  O O   . ARG B 1 71  ? 9.452   7.438   -1.400  1.00 41.22  ? 71  ARG B O   1 
ATOM   3904  C CB  . ARG B 1 71  ? 8.541   6.426   1.583   1.00 33.92  ? 71  ARG B CB  1 
ATOM   3905  C CG  . ARG B 1 71  ? 9.221   5.926   2.847   1.00 40.02  ? 71  ARG B CG  1 
ATOM   3906  C CD  . ARG B 1 71  ? 8.921   4.425   3.141   1.00 44.04  ? 71  ARG B CD  1 
ATOM   3907  N NE  . ARG B 1 71  ? 7.496   4.112   3.287   1.00 49.98  ? 71  ARG B NE  1 
ATOM   3908  C CZ  . ARG B 1 71  ? 6.716   4.628   4.211   1.00 54.88  ? 71  ARG B CZ  1 
ATOM   3909  N NH1 . ARG B 1 71  ? 7.242   5.338   5.192   1.00 55.60  ? 71  ARG B NH1 1 
ATOM   3910  N NH2 . ARG B 1 71  ? 5.416   4.432   4.157   1.00 55.29  ? 71  ARG B NH2 1 
ATOM   3911  N N   . ALA B 1 72  ? 7.599   8.491   -0.667  1.00 36.64  ? 72  ALA B N   1 
ATOM   3912  C CA  . ALA B 1 72  ? 7.084   8.748   -2.004  1.00 38.12  ? 72  ALA B CA  1 
ATOM   3913  C C   . ALA B 1 72  ? 8.037   9.674   -2.778  1.00 38.29  ? 72  ALA B C   1 
ATOM   3914  O O   . ALA B 1 72  ? 8.185   9.543   -4.001  1.00 36.44  ? 72  ALA B O   1 
ATOM   3915  C CB  . ALA B 1 72  ? 5.667   9.333   -1.923  1.00 35.79  ? 72  ALA B CB  1 
ATOM   3916  N N   . ALA B 1 73  ? 8.654   10.623  -2.062  1.00 34.65  ? 73  ALA B N   1 
ATOM   3917  C CA  . ALA B 1 73  ? 9.548   11.587  -2.672  1.00 34.54  ? 73  ALA B CA  1 
ATOM   3918  C C   . ALA B 1 73  ? 10.708  10.862  -3.384  1.00 39.51  ? 73  ALA B C   1 
ATOM   3919  O O   . ALA B 1 73  ? 11.108  11.256  -4.472  1.00 38.80  ? 73  ALA B O   1 
ATOM   3920  C CB  . ALA B 1 73  ? 10.048  12.552  -1.618  1.00 33.94  ? 73  ALA B CB  1 
ATOM   3921  N N   . VAL B 1 74  ? 11.234  9.792   -2.760  1.00 39.57  ? 74  VAL B N   1 
ATOM   3922  C CA  . VAL B 1 74  ? 12.350  9.046   -3.333  1.00 38.99  ? 74  VAL B CA  1 
ATOM   3923  C C   . VAL B 1 74  ? 11.907  8.396   -4.645  1.00 37.74  ? 74  VAL B C   1 
ATOM   3924  O O   . VAL B 1 74  ? 12.660  8.399   -5.623  1.00 35.41  ? 74  VAL B O   1 
ATOM   3925  C CB  . VAL B 1 74  ? 12.903  7.993   -2.360  1.00 37.17  ? 74  VAL B CB  1 
ATOM   3926  C CG1 . VAL B 1 74  ? 13.843  7.014   -3.054  1.00 38.21  ? 74  VAL B CG1 1 
ATOM   3927  C CG2 . VAL B 1 74  ? 13.594  8.633   -1.182  1.00 36.41  ? 74  VAL B CG2 1 
ATOM   3928  N N   . LEU B 1 75  ? 10.683  7.831   -4.653  1.00 39.34  ? 75  LEU B N   1 
ATOM   3929  C CA  . LEU B 1 75  ? 10.166  7.124   -5.825  1.00 38.71  ? 75  LEU B CA  1 
ATOM   3930  C C   . LEU B 1 75  ? 9.991   8.105   -6.990  1.00 41.11  ? 75  LEU B C   1 
ATOM   3931  O O   . LEU B 1 75  ? 10.279  7.770   -8.127  1.00 43.01  ? 75  LEU B O   1 
ATOM   3932  C CB  . LEU B 1 75  ? 8.855   6.415   -5.504  1.00 40.49  ? 75  LEU B CB  1 
ATOM   3933  C CG  . LEU B 1 75  ? 8.961   4.963   -5.025  1.00 43.06  ? 75  LEU B CG  1 
ATOM   3934  C CD1 . LEU B 1 75  ? 9.660   4.089   -6.072  1.00 43.09  ? 75  LEU B CD1 1 
ATOM   3935  C CD2 . LEU B 1 75  ? 9.654   4.867   -3.667  1.00 41.35  ? 75  LEU B CD2 1 
ATOM   3936  N N   . TYR B 1 76  ? 9.519   9.322   -6.695  1.00 45.92  ? 76  TYR B N   1 
ATOM   3937  C CA  . TYR B 1 76  ? 9.297   10.323  -7.736  1.00 45.31  ? 76  TYR B CA  1 
ATOM   3938  C C   . TYR B 1 76  ? 10.631  10.695  -8.384  1.00 46.60  ? 76  TYR B C   1 
ATOM   3939  O O   . TYR B 1 76  ? 10.717  10.797  -9.591  1.00 50.04  ? 76  TYR B O   1 
ATOM   3940  C CB  . TYR B 1 76  ? 8.594   11.558  -7.163  1.00 45.44  ? 76  TYR B CB  1 
ATOM   3941  C CG  . TYR B 1 76  ? 7.087   11.417  -7.056  1.00 44.09  ? 76  TYR B CG  1 
ATOM   3942  C CD1 . TYR B 1 76  ? 6.315   11.075  -8.167  1.00 45.37  ? 76  TYR B CD1 1 
ATOM   3943  C CD2 . TYR B 1 76  ? 6.441   11.547  -5.830  1.00 45.67  ? 76  TYR B CD2 1 
ATOM   3944  C CE1 . TYR B 1 76  ? 4.944   10.906  -8.067  1.00 45.24  ? 76  TYR B CE1 1 
ATOM   3945  C CE2 . TYR B 1 76  ? 5.070   11.399  -5.720  1.00 46.47  ? 76  TYR B CE2 1 
ATOM   3946  C CZ  . TYR B 1 76  ? 4.321   11.080  -6.843  1.00 46.29  ? 76  TYR B CZ  1 
ATOM   3947  O OH  . TYR B 1 76  ? 2.991   10.922  -6.729  1.00 48.43  ? 76  TYR B OH  1 
ATOM   3948  N N   . LYS B 1 77  ? 11.662  10.909  -7.564  1.00 50.16  ? 77  LYS B N   1 
ATOM   3949  C CA  . LYS B 1 77  ? 12.984  11.274  -8.070  1.00 53.55  ? 77  LYS B CA  1 
ATOM   3950  C C   . LYS B 1 77  ? 13.558  10.141  -8.938  1.00 48.68  ? 77  LYS B C   1 
ATOM   3951  O O   . LYS B 1 77  ? 14.293  10.404  -9.882  1.00 47.02  ? 77  LYS B O   1 
ATOM   3952  C CB  . LYS B 1 77  ? 13.924  11.646  -6.921  1.00 56.32  ? 77  LYS B CB  1 
ATOM   3953  C CG  . LYS B 1 77  ? 13.876  13.128  -6.532  1.00 63.27  ? 77  LYS B CG  1 
ATOM   3954  C CD  . LYS B 1 77  ? 14.585  13.465  -5.229  1.00 71.87  ? 77  LYS B CD  1 
ATOM   3955  C CE  . LYS B 1 77  ? 13.691  13.343  -4.020  1.00 76.62  ? 77  LYS B CE  1 
ATOM   3956  N NZ  . LYS B 1 77  ? 14.405  12.773  -2.858  1.00 76.51  ? 77  LYS B NZ  1 
ATOM   3957  N N   . ALA B 1 78  ? 13.201  8.884   -8.630  1.00 43.83  ? 78  ALA B N   1 
ATOM   3958  C CA  . ALA B 1 78  ? 13.687  7.753   -9.413  1.00 43.63  ? 78  ALA B CA  1 
ATOM   3959  C C   . ALA B 1 78  ? 13.150  7.836   -10.839 1.00 45.18  ? 78  ALA B C   1 
ATOM   3960  O O   . ALA B 1 78  ? 13.825  7.426   -11.784 1.00 44.96  ? 78  ALA B O   1 
ATOM   3961  C CB  . ALA B 1 78  ? 13.305  6.442   -8.752  1.00 42.44  ? 78  ALA B CB  1 
ATOM   3962  N N   . VAL B 1 79  ? 11.925  8.362   -10.981 1.00 47.82  ? 79  VAL B N   1 
ATOM   3963  C CA  . VAL B 1 79  ? 11.292  8.501   -12.285 1.00 50.59  ? 79  VAL B CA  1 
ATOM   3964  C C   . VAL B 1 79  ? 12.100  9.493   -13.128 1.00 49.45  ? 79  VAL B C   1 
ATOM   3965  O O   . VAL B 1 79  ? 12.305  9.272   -14.323 1.00 47.16  ? 79  VAL B O   1 
ATOM   3966  C CB  . VAL B 1 79  ? 9.810   8.941   -12.161 1.00 54.87  ? 79  VAL B CB  1 
ATOM   3967  C CG1 . VAL B 1 79  ? 9.132   9.050   -13.525 1.00 52.47  ? 79  VAL B CG1 1 
ATOM   3968  C CG2 . VAL B 1 79  ? 9.007   8.010   -11.240 1.00 53.36  ? 79  VAL B CG2 1 
ATOM   3969  N N   . GLU B 1 80  ? 12.567  10.575  -12.482 1.00 49.95  ? 80  GLU B N   1 
ATOM   3970  C CA  . GLU B 1 80  ? 13.334  11.626  -13.159 1.00 56.08  ? 80  GLU B CA  1 
ATOM   3971  C C   . GLU B 1 80  ? 14.658  11.064  -13.704 1.00 55.05  ? 80  GLU B C   1 
ATOM   3972  O O   . GLU B 1 80  ? 15.096  11.436  -14.805 1.00 48.74  ? 80  GLU B O   1 
ATOM   3973  C CB  . GLU B 1 80  ? 13.603  12.796  -12.213 1.00 61.61  ? 80  GLU B CB  1 
ATOM   3974  C CG  . GLU B 1 80  ? 12.498  13.843  -12.227 1.00 76.60  ? 80  GLU B CG  1 
ATOM   3975  C CD  . GLU B 1 80  ? 12.558  14.862  -11.096 1.00 85.15  ? 80  GLU B CD  1 
ATOM   3976  O OE1 . GLU B 1 80  ? 11.643  15.728  -11.046 1.00 82.69  ? 80  GLU B OE1 1 
ATOM   3977  O OE2 . GLU B 1 80  ? 13.507  14.808  -10.272 1.00 78.69  ? 80  GLU B OE2 1 
ATOM   3978  N N   . VAL B 1 81  ? 15.301  10.195  -12.908 1.00 48.71  ? 81  VAL B N   1 
ATOM   3979  C CA  . VAL B 1 81  ? 16.548  9.556   -13.301 1.00 43.94  ? 81  VAL B CA  1 
ATOM   3980  C C   . VAL B 1 81  ? 16.287  8.642   -14.491 1.00 41.64  ? 81  VAL B C   1 
ATOM   3981  O O   . VAL B 1 81  ? 17.094  8.581   -15.404 1.00 48.75  ? 81  VAL B O   1 
ATOM   3982  C CB  . VAL B 1 81  ? 17.172  8.778   -12.125 1.00 44.24  ? 81  VAL B CB  1 
ATOM   3983  C CG1 . VAL B 1 81  ? 18.442  8.042   -12.543 1.00 42.10  ? 81  VAL B CG1 1 
ATOM   3984  C CG2 . VAL B 1 81  ? 17.432  9.694   -10.909 1.00 39.32  ? 81  VAL B CG2 1 
ATOM   3985  N N   . PHE B 1 82  ? 15.145  7.951   -14.479 1.00 40.00  ? 82  PHE B N   1 
ATOM   3986  C CA  . PHE B 1 82  ? 14.801  7.044   -15.563 1.00 42.02  ? 82  PHE B CA  1 
ATOM   3987  C C   . PHE B 1 82  ? 14.765  7.816   -16.887 1.00 46.00  ? 82  PHE B C   1 
ATOM   3988  O O   . PHE B 1 82  ? 15.119  7.263   -17.938 1.00 44.64  ? 82  PHE B O   1 
ATOM   3989  C CB  . PHE B 1 82  ? 13.468  6.338   -15.317 1.00 39.70  ? 82  PHE B CB  1 
ATOM   3990  C CG  . PHE B 1 82  ? 13.591  4.927   -14.783 1.00 41.19  ? 82  PHE B CG  1 
ATOM   3991  C CD1 . PHE B 1 82  ? 13.717  4.692   -13.412 1.00 42.25  ? 82  PHE B CD1 1 
ATOM   3992  C CD2 . PHE B 1 82  ? 13.550  3.824   -15.648 1.00 40.39  ? 82  PHE B CD2 1 
ATOM   3993  C CE1 . PHE B 1 82  ? 13.830  3.396   -12.924 1.00 41.21  ? 82  PHE B CE1 1 
ATOM   3994  C CE2 . PHE B 1 82  ? 13.647  2.527   -15.151 1.00 38.75  ? 82  PHE B CE2 1 
ATOM   3995  C CZ  . PHE B 1 82  ? 13.801  2.314   -13.795 1.00 36.86  ? 82  PHE B CZ  1 
ATOM   3996  N N   . ASP B 1 83  ? 14.304  9.076   -16.837 1.00 45.81  ? 83  ASP B N   1 
ATOM   3997  C CA  . ASP B 1 83  ? 14.154  9.877   -18.051 1.00 52.71  ? 83  ASP B CA  1 
ATOM   3998  C C   . ASP B 1 83  ? 15.525  10.400  -18.498 1.00 50.19  ? 83  ASP B C   1 
ATOM   3999  O O   . ASP B 1 83  ? 15.892  10.256  -19.655 1.00 43.05  ? 83  ASP B O   1 
ATOM   4000  C CB  . ASP B 1 83  ? 13.132  10.990  -17.875 1.00 53.41  ? 83  ASP B CB  1 
ATOM   4001  C CG  . ASP B 1 83  ? 11.686  10.531  -17.774 1.00 54.18  ? 83  ASP B CG  1 
ATOM   4002  O OD1 . ASP B 1 83  ? 11.315  9.591   -18.509 1.00 57.80  ? 83  ASP B OD1 1 
ATOM   4003  O OD2 . ASP B 1 83  ? 10.958  11.097  -16.955 1.00 52.33  ? 83  ASP B OD2 1 
ATOM   4004  N N   . ARG B 1 84  ? 16.287  10.963  -17.552 1.00 53.16  ? 84  ARG B N   1 
ATOM   4005  C CA  . ARG B 1 84  ? 17.592  11.537  -17.852 1.00 52.74  ? 84  ARG B CA  1 
ATOM   4006  C C   . ARG B 1 84  ? 18.562  10.454  -18.343 1.00 51.83  ? 84  ARG B C   1 
ATOM   4007  O O   . ARG B 1 84  ? 19.409  10.746  -19.154 1.00 60.44  ? 84  ARG B O   1 
ATOM   4008  C CB  . ARG B 1 84  ? 18.166  12.242  -16.621 1.00 50.00  ? 84  ARG B CB  1 
ATOM   4009  C CG  . ARG B 1 84  ? 17.397  13.485  -16.204 1.00 50.00  ? 84  ARG B CG  1 
ATOM   4010  C CD  . ARG B 1 84  ? 17.994  14.214  -15.011 1.00 50.00  ? 84  ARG B CD  1 
ATOM   4011  N NE  . ARG B 1 84  ? 17.693  13.540  -13.751 1.00 50.00  ? 84  ARG B NE  1 
ATOM   4012  C CZ  . ARG B 1 84  ? 18.189  13.900  -12.577 1.00 50.00  ? 84  ARG B CZ  1 
ATOM   4013  N NH1 . ARG B 1 84  ? 19.012  14.938  -12.492 1.00 50.00  ? 84  ARG B NH1 1 
ATOM   4014  N NH2 . ARG B 1 84  ? 17.862  13.228  -11.480 1.00 50.00  ? 84  ARG B NH2 1 
ATOM   4015  N N   . ARG B 1 85  ? 18.430  9.203   -17.838 1.00 50.98  ? 85  ARG B N   1 
ATOM   4016  C CA  . ARG B 1 85  ? 19.362  8.121   -18.195 1.00 44.19  ? 85  ARG B CA  1 
ATOM   4017  C C   . ARG B 1 85  ? 18.685  7.082   -19.103 1.00 40.93  ? 85  ARG B C   1 
ATOM   4018  O O   . ARG B 1 85  ? 19.108  5.940   -19.151 1.00 36.43  ? 85  ARG B O   1 
ATOM   4019  C CB  . ARG B 1 85  ? 19.909  7.439   -16.941 1.00 43.01  ? 85  ARG B CB  1 
ATOM   4020  C CG  . ARG B 1 85  ? 20.539  8.403   -15.951 1.00 47.39  ? 85  ARG B CG  1 
ATOM   4021  C CD  . ARG B 1 85  ? 21.363  7.671   -14.911 1.00 50.38  ? 85  ARG B CD  1 
ATOM   4022  N NE  . ARG B 1 85  ? 22.072  8.580   -14.014 1.00 46.17  ? 85  ARG B NE  1 
ATOM   4023  C CZ  . ARG B 1 85  ? 23.329  8.974   -14.192 1.00 45.81  ? 85  ARG B CZ  1 
ATOM   4024  N NH1 . ARG B 1 85  ? 23.992  8.574   -15.251 1.00 45.80  ? 85  ARG B NH1 1 
ATOM   4025  N NH2 . ARG B 1 85  ? 23.903  9.790   -13.319 1.00 43.22  ? 85  ARG B NH2 1 
ATOM   4026  N N   . HIS B 1 86  ? 17.701  7.518   -19.891 1.00 44.26  ? 86  HIS B N   1 
ATOM   4027  C CA  . HIS B 1 86  ? 16.903  6.619   -20.717 1.00 42.48  ? 86  HIS B CA  1 
ATOM   4028  C C   . HIS B 1 86  ? 17.825  5.747   -21.582 1.00 39.13  ? 86  HIS B C   1 
ATOM   4029  O O   . HIS B 1 86  ? 17.773  4.517   -21.526 1.00 40.68  ? 86  HIS B O   1 
ATOM   4030  C CB  . HIS B 1 86  ? 15.879  7.445   -21.528 1.00 48.59  ? 86  HIS B CB  1 
ATOM   4031  C CG  . HIS B 1 86  ? 14.920  6.647   -22.374 1.00 50.44  ? 86  HIS B CG  1 
ATOM   4032  N ND1 . HIS B 1 86  ? 13.816  7.222   -22.982 1.00 48.79  ? 86  HIS B ND1 1 
ATOM   4033  C CD2 . HIS B 1 86  ? 14.900  5.351   -22.735 1.00 51.87  ? 86  HIS B CD2 1 
ATOM   4034  C CE1 . HIS B 1 86  ? 13.159  6.297   -23.683 1.00 46.82  ? 86  HIS B CE1 1 
ATOM   4035  N NE2 . HIS B 1 86  ? 13.791  5.154   -23.549 1.00 47.22  ? 86  HIS B NE2 1 
ATOM   4036  N N   . GLU B 1 87  ? 18.614  6.380   -22.429 1.00 41.49  ? 87  GLU B N   1 
ATOM   4037  C CA  . GLU B 1 87  ? 19.414  5.646   -23.409 1.00 44.05  ? 87  GLU B CA  1 
ATOM   4038  C C   . GLU B 1 87  ? 20.445  4.754   -22.693 1.00 39.49  ? 87  GLU B C   1 
ATOM   4039  O O   . GLU B 1 87  ? 20.720  3.630   -23.144 1.00 37.95  ? 87  GLU B O   1 
ATOM   4040  C CB  . GLU B 1 87  ? 20.097  6.627   -24.371 1.00 46.71  ? 87  GLU B CB  1 
ATOM   4041  C CG  . GLU B 1 87  ? 21.021  5.954   -25.384 1.00 48.75  ? 87  GLU B CG  1 
ATOM   4042  C CD  . GLU B 1 87  ? 20.422  4.780   -26.134 1.00 52.10  ? 87  GLU B CD  1 
ATOM   4043  O OE1 . GLU B 1 87  ? 19.247  4.865   -26.552 1.00 62.60  ? 87  GLU B OE1 1 
ATOM   4044  O OE2 . GLU B 1 87  ? 21.147  3.794   -26.325 1.00 56.97  ? 87  GLU B OE2 1 
ATOM   4045  N N   . GLU B 1 88  ? 21.055  5.289   -21.608 1.00 38.40  ? 88  GLU B N   1 
ATOM   4046  C CA  . GLU B 1 88  ? 22.053  4.545   -20.825 1.00 38.68  ? 88  GLU B CA  1 
ATOM   4047  C C   . GLU B 1 88  ? 21.443  3.217   -20.362 1.00 38.56  ? 88  GLU B C   1 
ATOM   4048  O O   . GLU B 1 88  ? 22.080  2.161   -20.441 1.00 40.32  ? 88  GLU B O   1 
ATOM   4049  C CB  . GLU B 1 88  ? 22.536  5.407   -19.664 1.00 41.60  ? 88  GLU B CB  1 
ATOM   4050  C CG  . GLU B 1 88  ? 23.410  4.671   -18.653 1.00 41.19  ? 88  GLU B CG  1 
ATOM   4051  C CD  . GLU B 1 88  ? 23.941  5.600   -17.553 1.00 41.33  ? 88  GLU B CD  1 
ATOM   4052  O OE1 . GLU B 1 88  ? 23.541  6.806   -17.527 1.00 41.18  ? 88  GLU B OE1 1 
ATOM   4053  O OE2 . GLU B 1 88  ? 24.750  5.140   -16.730 1.00 43.35  ? 88  GLU B OE2 1 
ATOM   4054  N N   . ILE B 1 89  ? 20.181  3.279   -19.946 1.00 39.16  ? 89  ILE B N   1 
ATOM   4055  C CA  . ILE B 1 89  ? 19.510  2.132   -19.387 1.00 39.86  ? 89  ILE B CA  1 
ATOM   4056  C C   . ILE B 1 89  ? 19.217  1.149   -20.504 1.00 40.73  ? 89  ILE B C   1 
ATOM   4057  O O   . ILE B 1 89  ? 19.470  -0.063  -20.365 1.00 40.14  ? 89  ILE B O   1 
ATOM   4058  C CB  . ILE B 1 89  ? 18.246  2.567   -18.618 1.00 37.89  ? 89  ILE B CB  1 
ATOM   4059  C CG1 . ILE B 1 89  ? 18.621  3.316   -17.361 1.00 37.68  ? 89  ILE B CG1 1 
ATOM   4060  C CG2 . ILE B 1 89  ? 17.352  1.368   -18.308 1.00 40.03  ? 89  ILE B CG2 1 
ATOM   4061  C CD1 . ILE B 1 89  ? 17.547  4.253   -16.849 1.00 42.10  ? 89  ILE B CD1 1 
ATOM   4062  N N   . VAL B 1 90  ? 18.675  1.670   -21.602 1.00 42.21  ? 90  VAL B N   1 
ATOM   4063  C CA  . VAL B 1 90  ? 18.290  0.840   -22.741 1.00 43.17  ? 90  VAL B CA  1 
ATOM   4064  C C   . VAL B 1 90  ? 19.535  0.154   -23.308 1.00 41.07  ? 90  VAL B C   1 
ATOM   4065  O O   . VAL B 1 90  ? 19.515  -1.056  -23.620 1.00 32.48  ? 90  VAL B O   1 
ATOM   4066  C CB  . VAL B 1 90  ? 17.567  1.701   -23.805 1.00 51.47  ? 90  VAL B CB  1 
ATOM   4067  C CG1 . VAL B 1 90  ? 17.615  1.064   -25.198 1.00 49.00  ? 90  VAL B CG1 1 
ATOM   4068  C CG2 . VAL B 1 90  ? 16.118  2.011   -23.386 1.00 50.80  ? 90  VAL B CG2 1 
ATOM   4069  N N   . ASP B 1 91  ? 20.634  0.914   -23.393 1.00 44.09  ? 91  ASP B N   1 
ATOM   4070  C CA  . ASP B 1 91  ? 21.877  0.385   -23.933 1.00 48.64  ? 91  ASP B CA  1 
ATOM   4071  C C   . ASP B 1 91  ? 22.382  -0.775  -23.060 1.00 44.07  ? 91  ASP B C   1 
ATOM   4072  O O   . ASP B 1 91  ? 22.852  -1.801  -23.582 1.00 43.33  ? 91  ASP B O   1 
ATOM   4073  C CB  . ASP B 1 91  ? 22.903  1.483   -24.120 1.00 55.01  ? 91  ASP B CB  1 
ATOM   4074  C CG  . ASP B 1 91  ? 24.190  1.043   -24.791 1.00 52.84  ? 91  ASP B CG  1 
ATOM   4075  O OD1 . ASP B 1 91  ? 24.115  0.223   -25.736 1.00 52.09  ? 91  ASP B OD1 1 
ATOM   4076  O OD2 . ASP B 1 91  ? 25.241  1.522   -24.374 1.00 55.01  ? 91  ASP B OD2 1 
ATOM   4077  N N   . TRP B 1 92  ? 22.268  -0.619  -21.734 1.00 44.32  ? 92  TRP B N   1 
ATOM   4078  C CA  . TRP B 1 92  ? 22.704  -1.660  -20.810 1.00 37.03  ? 92  TRP B CA  1 
ATOM   4079  C C   . TRP B 1 92  ? 21.841  -2.918  -20.976 1.00 37.38  ? 92  TRP B C   1 
ATOM   4080  O O   . TRP B 1 92  ? 22.349  -4.032  -20.916 1.00 36.94  ? 92  TRP B O   1 
ATOM   4081  C CB  . TRP B 1 92  ? 22.678  -1.149  -19.368 1.00 37.47  ? 92  TRP B CB  1 
ATOM   4082  C CG  . TRP B 1 92  ? 24.024  -0.721  -18.852 1.00 38.07  ? 92  TRP B CG  1 
ATOM   4083  C CD1 . TRP B 1 92  ? 24.402  0.532   -18.449 1.00 34.66  ? 92  TRP B CD1 1 
ATOM   4084  C CD2 . TRP B 1 92  ? 25.187  -1.565  -18.694 1.00 34.04  ? 92  TRP B CD2 1 
ATOM   4085  N NE1 . TRP B 1 92  ? 25.717  0.524   -18.050 1.00 35.66  ? 92  TRP B NE1 1 
ATOM   4086  C CE2 . TRP B 1 92  ? 26.224  -0.748  -18.190 1.00 33.57  ? 92  TRP B CE2 1 
ATOM   4087  C CE3 . TRP B 1 92  ? 25.444  -2.909  -18.929 1.00 35.52  ? 92  TRP B CE3 1 
ATOM   4088  C CZ2 . TRP B 1 92  ? 27.496  -1.241  -17.931 1.00 33.82  ? 92  TRP B CZ2 1 
ATOM   4089  C CZ3 . TRP B 1 92  ? 26.698  -3.406  -18.634 1.00 39.34  ? 92  TRP B CZ3 1 
ATOM   4090  C CH2 . TRP B 1 92  ? 27.712  -2.576  -18.154 1.00 36.18  ? 92  TRP B CH2 1 
ATOM   4091  N N   . ILE B 1 93  ? 20.533  -2.743  -21.193 1.00 36.62  ? 93  ILE B N   1 
ATOM   4092  C CA  . ILE B 1 93  ? 19.658  -3.895  -21.374 1.00 40.30  ? 93  ILE B CA  1 
ATOM   4093  C C   . ILE B 1 93  ? 20.112  -4.659  -22.623 1.00 42.16  ? 93  ILE B C   1 
ATOM   4094  O O   . ILE B 1 93  ? 20.212  -5.880  -22.600 1.00 39.59  ? 93  ILE B O   1 
ATOM   4095  C CB  . ILE B 1 93  ? 18.171  -3.470  -21.447 1.00 48.74  ? 93  ILE B CB  1 
ATOM   4096  C CG1 . ILE B 1 93  ? 17.653  -3.008  -20.079 1.00 55.84  ? 93  ILE B CG1 1 
ATOM   4097  C CG2 . ILE B 1 93  ? 17.292  -4.589  -22.019 1.00 45.19  ? 93  ILE B CG2 1 
ATOM   4098  C CD1 . ILE B 1 93  ? 16.544  -1.979  -20.155 1.00 60.54  ? 93  ILE B CD1 1 
ATOM   4099  N N   . ILE B 1 94  ? 20.375  -3.922  -23.714 1.00 45.75  ? 94  ILE B N   1 
ATOM   4100  C CA  . ILE B 1 94  ? 20.716  -4.543  -24.986 1.00 53.24  ? 94  ILE B CA  1 
ATOM   4101  C C   . ILE B 1 94  ? 22.039  -5.286  -24.851 1.00 52.20  ? 94  ILE B C   1 
ATOM   4102  O O   . ILE B 1 94  ? 22.116  -6.477  -25.158 1.00 53.21  ? 94  ILE B O   1 
ATOM   4103  C CB  . ILE B 1 94  ? 20.790  -3.505  -26.112 1.00 55.70  ? 94  ILE B CB  1 
ATOM   4104  C CG1 . ILE B 1 94  ? 19.445  -2.808  -26.346 1.00 54.78  ? 94  ILE B CG1 1 
ATOM   4105  C CG2 . ILE B 1 94  ? 21.322  -4.152  -27.388 1.00 55.06  ? 94  ILE B CG2 1 
ATOM   4106  C CD1 . ILE B 1 94  ? 19.565  -1.428  -26.993 1.00 53.07  ? 94  ILE B CD1 1 
ATOM   4107  N N   . ARG B 1 95  ? 23.082  -4.560  -24.415 1.00 52.83  ? 95  ARG B N   1 
ATOM   4108  C CA  . ARG B 1 95  ? 24.433  -5.109  -24.349 1.00 53.59  ? 95  ARG B CA  1 
ATOM   4109  C C   . ARG B 1 95  ? 24.470  -6.358  -23.456 1.00 45.79  ? 95  ARG B C   1 
ATOM   4110  O O   . ARG B 1 95  ? 24.995  -7.387  -23.857 1.00 44.80  ? 95  ARG B O   1 
ATOM   4111  C CB  . ARG B 1 95  ? 25.416  -4.058  -23.829 1.00 50.00  ? 95  ARG B CB  1 
ATOM   4112  C CG  . ARG B 1 95  ? 25.630  -2.887  -24.775 1.00 50.00  ? 95  ARG B CG  1 
ATOM   4113  C CD  . ARG B 1 95  ? 26.643  -1.867  -24.281 1.00 50.00  ? 95  ARG B CD  1 
ATOM   4114  N NE  . ARG B 1 95  ? 26.761  -0.729  -25.188 1.00 50.00  ? 95  ARG B NE  1 
ATOM   4115  C CZ  . ARG B 1 95  ? 27.486  0.351   -24.937 1.00 50.00  ? 95  ARG B CZ  1 
ATOM   4116  N NH1 . ARG B 1 95  ? 28.168  0.447   -23.802 1.00 50.00  ? 95  ARG B NH1 1 
ATOM   4117  N NH2 . ARG B 1 95  ? 27.536  1.340   -25.821 1.00 50.00  ? 95  ARG B NH2 1 
ATOM   4118  N N   . GLU B 1 96  ? 23.964  -6.219  -22.200 1.00 44.67  ? 96  GLU B N   1 
ATOM   4119  C CA  . GLU B 1 96  ? 24.145  -7.233  -21.154 1.00 42.64  ? 96  GLU B CA  1 
ATOM   4120  C C   . GLU B 1 96  ? 23.223  -8.433  -21.399 1.00 40.73  ? 96  GLU B C   1 
ATOM   4121  O O   . GLU B 1 96  ? 23.682  -9.566  -21.357 1.00 40.51  ? 96  GLU B O   1 
ATOM   4122  C CB  . GLU B 1 96  ? 23.926  -6.670  -19.742 1.00 49.31  ? 96  GLU B CB  1 
ATOM   4123  C CG  . GLU B 1 96  ? 24.351  -7.643  -18.620 1.00 55.19  ? 96  GLU B CG  1 
ATOM   4124  C CD  . GLU B 1 96  ? 24.000  -7.202  -17.176 1.00 62.13  ? 96  GLU B CD  1 
ATOM   4125  O OE1 . GLU B 1 96  ? 24.855  -7.385  -16.250 1.00 56.95  ? 96  GLU B OE1 1 
ATOM   4126  O OE2 . GLU B 1 96  ? 22.857  -6.693  -16.976 1.00 57.09  ? 96  GLU B OE2 1 
ATOM   4127  N N   . SER B 1 97  ? 21.909  -8.176  -21.625 1.00 43.11  ? 97  SER B N   1 
ATOM   4128  C CA  . SER B 1 97  ? 20.908  -9.259  -21.715 1.00 48.30  ? 97  SER B CA  1 
ATOM   4129  C C   . SER B 1 97  ? 20.831  -9.823  -23.139 1.00 50.94  ? 97  SER B C   1 
ATOM   4130  O O   . SER B 1 97  ? 20.359  -10.941 -23.328 1.00 43.80  ? 97  SER B O   1 
ATOM   4131  C CB  . SER B 1 97  ? 19.539  -8.807  -21.251 1.00 45.30  ? 97  SER B CB  1 
ATOM   4132  O OG  . SER B 1 97  ? 18.972  -7.878  -22.155 1.00 42.54  ? 97  SER B OG  1 
ATOM   4133  N N   . GLY B 1 98  ? 21.277  -9.025  -24.135 1.00 49.51  ? 98  GLY B N   1 
ATOM   4134  C CA  . GLY B 1 98  ? 21.162  -9.405  -25.533 1.00 54.16  ? 98  GLY B CA  1 
ATOM   4135  C C   . GLY B 1 98  ? 19.774  -9.084  -26.086 1.00 59.59  ? 98  GLY B C   1 
ATOM   4136  O O   . GLY B 1 98  ? 19.391  -9.575  -27.151 1.00 64.93  ? 98  GLY B O   1 
ATOM   4137  N N   . SER B 1 99  ? 19.035  -8.245  -25.350 1.00 66.82  ? 99  SER B N   1 
ATOM   4138  C CA  . SER B 1 99  ? 17.700  -7.811  -25.749 1.00 61.12  ? 99  SER B CA  1 
ATOM   4139  C C   . SER B 1 99  ? 17.782  -6.915  -26.989 1.00 60.04  ? 99  SER B C   1 
ATOM   4140  O O   . SER B 1 99  ? 18.675  -6.065  -27.082 1.00 58.77  ? 99  SER B O   1 
ATOM   4141  C CB  . SER B 1 99  ? 17.024  -7.095  -24.626 1.00 59.96  ? 99  SER B CB  1 
ATOM   4142  O OG  . SER B 1 99  ? 15.929  -6.318  -25.092 1.00 65.87  ? 99  SER B OG  1 
ATOM   4143  N N   . THR B 1 100 ? 16.779  -7.039  -27.887 1.00 58.33  ? 100 THR B N   1 
ATOM   4144  C CA  . THR B 1 100 ? 16.658  -6.124  -29.022 1.00 52.09  ? 100 THR B CA  1 
ATOM   4145  C C   . THR B 1 100 ? 16.292  -4.757  -28.490 1.00 49.58  ? 100 THR B C   1 
ATOM   4146  O O   . THR B 1 100 ? 15.677  -4.639  -27.437 1.00 52.39  ? 100 THR B O   1 
ATOM   4147  C CB  . THR B 1 100 ? 15.630  -6.601  -30.053 1.00 52.70  ? 100 THR B CB  1 
ATOM   4148  O OG1 . THR B 1 100 ? 14.356  -6.368  -29.447 1.00 56.09  ? 100 THR B OG1 1 
ATOM   4149  C CG2 . THR B 1 100 ? 15.834  -8.053  -30.470 1.00 56.35  ? 100 THR B CG2 1 
ATOM   4150  N N   . ARG B 1 101 ? 16.689  -3.736  -29.230 1.00 47.72  ? 101 ARG B N   1 
ATOM   4151  C CA  . ARG B 1 101 ? 16.414  -2.365  -28.870 1.00 47.11  ? 101 ARG B CA  1 
ATOM   4152  C C   . ARG B 1 101 ? 14.901  -2.147  -28.730 1.00 55.07  ? 101 ARG B C   1 
ATOM   4153  O O   . ARG B 1 101 ? 14.464  -1.353  -27.907 1.00 65.78  ? 101 ARG B O   1 
ATOM   4154  C CB  . ARG B 1 101 ? 17.066  -1.460  -29.909 1.00 48.29  ? 101 ARG B CB  1 
ATOM   4155  C CG  . ARG B 1 101 ? 16.556  -0.037  -29.926 1.00 50.95  ? 101 ARG B CG  1 
ATOM   4156  C CD  . ARG B 1 101 ? 17.592  0.907   -30.519 1.00 50.36  ? 101 ARG B CD  1 
ATOM   4157  N NE  . ARG B 1 101 ? 18.273  1.675   -29.477 1.00 49.14  ? 101 ARG B NE  1 
ATOM   4158  C CZ  . ARG B 1 101 ? 19.538  1.607   -29.212 1.00 59.80  ? 101 ARG B CZ  1 
ATOM   4159  N NH1 . ARG B 1 101 ? 20.273  0.669   -29.768 1.00 70.56  ? 101 ARG B NH1 1 
ATOM   4160  N NH2 . ARG B 1 101 ? 20.081  2.464   -28.369 1.00 62.43  ? 101 ARG B NH2 1 
ATOM   4161  N N   . LEU B 1 102 ? 14.108  -2.884  -29.500 1.00 58.93  ? 102 LEU B N   1 
ATOM   4162  C CA  . LEU B 1 102 ? 12.653  -2.727  -29.469 1.00 65.89  ? 102 LEU B CA  1 
ATOM   4163  C C   . LEU B 1 102 ? 12.105  -3.190  -28.104 1.00 58.49  ? 102 LEU B C   1 
ATOM   4164  O O   . LEU B 1 102 ? 11.325  -2.485  -27.468 1.00 56.68  ? 102 LEU B O   1 
ATOM   4165  C CB  . LEU B 1 102 ? 12.049  -3.524  -30.635 1.00 73.77  ? 102 LEU B CB  1 
ATOM   4166  C CG  . LEU B 1 102 ? 10.519  -3.516  -30.750 1.00 76.04  ? 102 LEU B CG  1 
ATOM   4167  C CD1 . LEU B 1 102 ? 9.988   -2.107  -30.876 1.00 76.49  ? 102 LEU B CD1 1 
ATOM   4168  C CD2 . LEU B 1 102 ? 10.064  -4.364  -31.922 1.00 79.84  ? 102 LEU B CD2 1 
ATOM   4169  N N   . LYS B 1 103 ? 12.540  -4.384  -27.683 1.00 57.24  ? 103 LYS B N   1 
ATOM   4170  C CA  . LYS B 1 103 ? 12.204  -4.961  -26.391 1.00 63.08  ? 103 LYS B CA  1 
ATOM   4171  C C   . LYS B 1 103 ? 12.779  -4.120  -25.227 1.00 62.46  ? 103 LYS B C   1 
ATOM   4172  O O   . LYS B 1 103 ? 12.145  -4.001  -24.177 1.00 51.86  ? 103 LYS B O   1 
ATOM   4173  C CB  . LYS B 1 103 ? 12.759  -6.379  -26.363 1.00 70.61  ? 103 LYS B CB  1 
ATOM   4174  C CG  . LYS B 1 103 ? 12.993  -6.925  -24.984 1.00 93.21  ? 103 LYS B CG  1 
ATOM   4175  C CD  . LYS B 1 103 ? 13.244  -8.430  -24.953 1.00 108.53 ? 103 LYS B CD  1 
ATOM   4176  C CE  . LYS B 1 103 ? 14.333  -8.838  -23.978 1.00 127.24 ? 103 LYS B CE  1 
ATOM   4177  N NZ  . LYS B 1 103 ? 13.859  -9.666  -22.867 1.00 138.52 ? 103 LYS B NZ  1 
ATOM   4178  N N   . ALA B 1 104 ? 14.010  -3.607  -25.393 1.00 58.46  ? 104 ALA B N   1 
ATOM   4179  C CA  . ALA B 1 104 ? 14.648  -2.807  -24.352 1.00 54.19  ? 104 ALA B CA  1 
ATOM   4180  C C   . ALA B 1 104 ? 13.809  -1.567  -24.063 1.00 53.76  ? 104 ALA B C   1 
ATOM   4181  O O   . ALA B 1 104 ? 13.656  -1.177  -22.912 1.00 54.20  ? 104 ALA B O   1 
ATOM   4182  C CB  . ALA B 1 104 ? 16.074  -2.433  -24.753 1.00 56.91  ? 104 ALA B CB  1 
ATOM   4183  N N   . GLU B 1 105 ? 13.253  -0.961  -25.117 1.00 56.92  ? 105 GLU B N   1 
ATOM   4184  C CA  . GLU B 1 105 ? 12.455  0.252   -24.964 1.00 57.47  ? 105 GLU B CA  1 
ATOM   4185  C C   . GLU B 1 105 ? 11.162  -0.075  -24.209 1.00 52.83  ? 105 GLU B C   1 
ATOM   4186  O O   . GLU B 1 105 ? 10.689  0.724   -23.387 1.00 52.59  ? 105 GLU B O   1 
ATOM   4187  C CB  . GLU B 1 105 ? 12.191  0.905   -26.324 1.00 54.36  ? 105 GLU B CB  1 
ATOM   4188  C CG  . GLU B 1 105 ? 13.400  1.674   -26.862 1.00 52.58  ? 105 GLU B CG  1 
ATOM   4189  C CD  . GLU B 1 105 ? 13.686  3.020   -26.192 1.00 58.33  ? 105 GLU B CD  1 
ATOM   4190  O OE1 . GLU B 1 105 ? 12.796  3.556   -25.506 1.00 63.90  ? 105 GLU B OE1 1 
ATOM   4191  O OE2 . GLU B 1 105 ? 14.817  3.533   -26.351 1.00 63.38  ? 105 GLU B OE2 1 
ATOM   4192  N N   . ILE B 1 106 ? 10.605  -1.249  -24.474 1.00 47.77  ? 106 ILE B N   1 
ATOM   4193  C CA  . ILE B 1 106 ? 9.391   -1.676  -23.780 1.00 54.17  ? 106 ILE B CA  1 
ATOM   4194  C C   . ILE B 1 106 ? 9.712   -1.914  -22.287 1.00 52.02  ? 106 ILE B C   1 
ATOM   4195  O O   . ILE B 1 106 ? 8.959   -1.496  -21.417 1.00 53.32  ? 106 ILE B O   1 
ATOM   4196  C CB  . ILE B 1 106 ? 8.784   -2.922  -24.453 1.00 48.60  ? 106 ILE B CB  1 
ATOM   4197  C CG1 . ILE B 1 106 ? 8.325   -2.614  -25.845 1.00 51.80  ? 106 ILE B CG1 1 
ATOM   4198  C CG2 . ILE B 1 106 ? 7.655   -3.510  -23.612 1.00 50.78  ? 106 ILE B CG2 1 
ATOM   4199  C CD1 . ILE B 1 106 ? 8.218   -3.829  -26.739 1.00 56.40  ? 106 ILE B CD1 1 
ATOM   4200  N N   . GLU B 1 107 ? 10.832  -2.597  -22.020 1.00 52.63  ? 107 GLU B N   1 
ATOM   4201  C CA  . GLU B 1 107 ? 11.261  -2.894  -20.665 1.00 48.20  ? 107 GLU B CA  1 
ATOM   4202  C C   . GLU B 1 107 ? 11.461  -1.588  -19.901 1.00 46.05  ? 107 GLU B C   1 
ATOM   4203  O O   . GLU B 1 107 ? 11.056  -1.480  -18.738 1.00 46.82  ? 107 GLU B O   1 
ATOM   4204  C CB  . GLU B 1 107 ? 12.522  -3.754  -20.684 1.00 51.06  ? 107 GLU B CB  1 
ATOM   4205  C CG  . GLU B 1 107 ? 13.041  -4.105  -19.290 1.00 60.15  ? 107 GLU B CG  1 
ATOM   4206  C CD  . GLU B 1 107 ? 13.862  -5.387  -19.227 1.00 57.52  ? 107 GLU B CD  1 
ATOM   4207  O OE1 . GLU B 1 107 ? 14.294  -5.849  -20.291 1.00 60.78  ? 107 GLU B OE1 1 
ATOM   4208  O OE2 . GLU B 1 107 ? 14.026  -5.941  -18.123 1.00 62.99  ? 107 GLU B OE2 1 
ATOM   4209  N N   . TRP B 1 108 ? 12.047  -0.583  -20.572 1.00 42.39  ? 108 TRP B N   1 
ATOM   4210  C CA  . TRP B 1 108 ? 12.285  0.704   -19.936 1.00 45.16  ? 108 TRP B CA  1 
ATOM   4211  C C   . TRP B 1 108 ? 10.947  1.341   -19.527 1.00 48.47  ? 108 TRP B C   1 
ATOM   4212  O O   . TRP B 1 108 ? 10.794  1.835   -18.400 1.00 47.48  ? 108 TRP B O   1 
ATOM   4213  C CB  . TRP B 1 108 ? 13.091  1.635   -20.854 1.00 42.28  ? 108 TRP B CB  1 
ATOM   4214  C CG  . TRP B 1 108 ? 13.283  3.014   -20.282 1.00 39.11  ? 108 TRP B CG  1 
ATOM   4215  C CD1 . TRP B 1 108 ? 14.254  3.412   -19.421 1.00 41.62  ? 108 TRP B CD1 1 
ATOM   4216  C CD2 . TRP B 1 108 ? 12.436  4.163   -20.490 1.00 40.56  ? 108 TRP B CD2 1 
ATOM   4217  N NE1 . TRP B 1 108 ? 14.082  4.737   -19.083 1.00 43.35  ? 108 TRP B NE1 1 
ATOM   4218  C CE2 . TRP B 1 108 ? 12.971  5.216   -19.713 1.00 39.47  ? 108 TRP B CE2 1 
ATOM   4219  C CE3 . TRP B 1 108 ? 11.272  4.401   -21.241 1.00 42.41  ? 108 TRP B CE3 1 
ATOM   4220  C CZ2 . TRP B 1 108 ? 12.389  6.477   -19.669 1.00 44.58  ? 108 TRP B CZ2 1 
ATOM   4221  C CZ3 . TRP B 1 108 ? 10.697  5.655   -21.198 1.00 44.95  ? 108 TRP B CZ3 1 
ATOM   4222  C CH2 . TRP B 1 108 ? 11.246  6.675   -20.420 1.00 45.68  ? 108 TRP B CH2 1 
ATOM   4223  N N   . GLY B 1 109 ? 9.991   1.342   -20.454 1.00 48.12  ? 109 GLY B N   1 
ATOM   4224  C CA  . GLY B 1 109 ? 8.704   1.968   -20.215 1.00 45.11  ? 109 GLY B CA  1 
ATOM   4225  C C   . GLY B 1 109 ? 7.947   1.273   -19.084 1.00 46.17  ? 109 GLY B C   1 
ATOM   4226  O O   . GLY B 1 109 ? 7.347   1.944   -18.222 1.00 44.94  ? 109 GLY B O   1 
ATOM   4227  N N   . ALA B 1 110 ? 7.988   -0.073  -19.084 1.00 37.95  ? 110 ALA B N   1 
ATOM   4228  C CA  . ALA B 1 110 ? 7.328   -0.859  -18.051 1.00 38.20  ? 110 ALA B CA  1 
ATOM   4229  C C   . ALA B 1 110 ? 7.916   -0.524  -16.678 1.00 39.67  ? 110 ALA B C   1 
ATOM   4230  O O   . ALA B 1 110 ? 7.175   -0.257  -15.753 1.00 48.06  ? 110 ALA B O   1 
ATOM   4231  C CB  . ALA B 1 110 ? 7.432   -2.354  -18.357 1.00 37.06  ? 110 ALA B CB  1 
ATOM   4232  N N   . ALA B 1 111 ? 9.255   -0.499  -16.579 1.00 38.40  ? 111 ALA B N   1 
ATOM   4233  C CA  . ALA B 1 111 ? 9.937   -0.227  -15.317 1.00 38.52  ? 111 ALA B CA  1 
ATOM   4234  C C   . ALA B 1 111 ? 9.648   1.192   -14.826 1.00 40.33  ? 111 ALA B C   1 
ATOM   4235  O O   . ALA B 1 111 ? 9.474   1.414   -13.616 1.00 43.30  ? 111 ALA B O   1 
ATOM   4236  C CB  . ALA B 1 111 ? 11.406  -0.447  -15.475 1.00 40.24  ? 111 ALA B CB  1 
ATOM   4237  N N   . ARG B 1 112 ? 9.613   2.146   -15.755 1.00 38.44  ? 112 ARG B N   1 
ATOM   4238  C CA  . ARG B 1 112 ? 9.313   3.527   -15.424 1.00 39.26  ? 112 ARG B CA  1 
ATOM   4239  C C   . ARG B 1 112 ? 7.889   3.640   -14.860 1.00 40.80  ? 112 ARG B C   1 
ATOM   4240  O O   . ARG B 1 112 ? 7.650   4.381   -13.898 1.00 47.65  ? 112 ARG B O   1 
ATOM   4241  C CB  . ARG B 1 112 ? 9.469   4.431   -16.655 1.00 41.46  ? 112 ARG B CB  1 
ATOM   4242  C CG  . ARG B 1 112 ? 9.372   5.918   -16.319 1.00 40.98  ? 112 ARG B CG  1 
ATOM   4243  C CD  . ARG B 1 112 ? 8.943   6.749   -17.493 1.00 42.79  ? 112 ARG B CD  1 
ATOM   4244  N NE  . ARG B 1 112 ? 8.923   8.183   -17.172 1.00 43.58  ? 112 ARG B NE  1 
ATOM   4245  C CZ  . ARG B 1 112 ? 7.833   8.891   -16.919 1.00 42.61  ? 112 ARG B CZ  1 
ATOM   4246  N NH1 . ARG B 1 112 ? 6.657   8.314   -16.935 1.00 47.53  ? 112 ARG B NH1 1 
ATOM   4247  N NH2 . ARG B 1 112 ? 7.928   10.167  -16.622 1.00 42.95  ? 112 ARG B NH2 1 
ATOM   4248  N N   . ALA B 1 113 ? 6.946   2.917   -15.459 1.00 39.33  ? 113 ALA B N   1 
ATOM   4249  C CA  . ALA B 1 113 ? 5.551   3.024   -15.046 1.00 43.57  ? 113 ALA B CA  1 
ATOM   4250  C C   . ALA B 1 113 ? 5.370   2.452   -13.629 1.00 43.83  ? 113 ALA B C   1 
ATOM   4251  O O   . ALA B 1 113 ? 4.616   3.011   -12.821 1.00 39.98  ? 113 ALA B O   1 
ATOM   4252  C CB  . ALA B 1 113 ? 4.654   2.332   -16.050 1.00 44.00  ? 113 ALA B CB  1 
ATOM   4253  N N   . ILE B 1 114 ? 6.069   1.339   -13.340 1.00 43.14  ? 114 ILE B N   1 
ATOM   4254  C CA  . ILE B 1 114 ? 6.024   0.723   -12.031 1.00 42.93  ? 114 ILE B CA  1 
ATOM   4255  C C   . ILE B 1 114 ? 6.513   1.733   -10.998 1.00 40.98  ? 114 ILE B C   1 
ATOM   4256  O O   . ILE B 1 114 ? 5.929   1.849   -9.918  1.00 33.43  ? 114 ILE B O   1 
ATOM   4257  C CB  . ILE B 1 114 ? 6.860   -0.571  -11.994 1.00 50.79  ? 114 ILE B CB  1 
ATOM   4258  C CG1 . ILE B 1 114 ? 6.295   -1.636  -12.896 1.00 62.28  ? 114 ILE B CG1 1 
ATOM   4259  C CG2 . ILE B 1 114 ? 7.015   -1.083  -10.568 1.00 53.46  ? 114 ILE B CG2 1 
ATOM   4260  C CD1 . ILE B 1 114 ? 4.791   -1.583  -13.052 1.00 74.12  ? 114 ILE B CD1 1 
ATOM   4261  N N   . THR B 1 115 ? 7.588   2.458   -11.342 1.00 39.88  ? 115 THR B N   1 
ATOM   4262  C CA  . THR B 1 115 ? 8.205   3.392   -10.406 1.00 42.92  ? 115 THR B CA  1 
ATOM   4263  C C   . THR B 1 115 ? 7.227   4.523   -10.089 1.00 42.35  ? 115 THR B C   1 
ATOM   4264  O O   . THR B 1 115 ? 7.123   4.941   -8.950  1.00 41.24  ? 115 THR B O   1 
ATOM   4265  C CB  . THR B 1 115 ? 9.517   3.945   -10.957 1.00 40.03  ? 115 THR B CB  1 
ATOM   4266  O OG1 . THR B 1 115 ? 10.278  2.843   -11.457 1.00 35.15  ? 115 THR B OG1 1 
ATOM   4267  C CG2 . THR B 1 115 ? 10.298  4.684   -9.891  1.00 42.69  ? 115 THR B CG2 1 
ATOM   4268  N N   . LEU B 1 116 ? 6.521   5.021   -11.109 1.00 46.88  ? 116 LEU B N   1 
ATOM   4269  C CA  . LEU B 1 116 ? 5.593   6.141   -10.914 1.00 49.73  ? 116 LEU B CA  1 
ATOM   4270  C C   . LEU B 1 116 ? 4.423   5.704   -10.020 1.00 49.20  ? 116 LEU B C   1 
ATOM   4271  O O   . LEU B 1 116 ? 4.029   6.421   -9.095  1.00 43.35  ? 116 LEU B O   1 
ATOM   4272  C CB  . LEU B 1 116 ? 5.089   6.660   -12.264 1.00 51.45  ? 116 LEU B CB  1 
ATOM   4273  C CG  . LEU B 1 116 ? 4.120   7.852   -12.213 1.00 50.13  ? 116 LEU B CG  1 
ATOM   4274  C CD1 . LEU B 1 116 ? 4.695   9.022   -11.399 1.00 48.16  ? 116 LEU B CD1 1 
ATOM   4275  C CD2 . LEU B 1 116 ? 3.751   8.291   -13.633 1.00 47.83  ? 116 LEU B CD2 1 
ATOM   4276  N N   . GLU B 1 117 ? 3.838   4.560   -10.347 1.00 48.34  ? 117 GLU B N   1 
ATOM   4277  C CA  . GLU B 1 117 ? 2.641   4.098   -9.675  1.00 49.47  ? 117 GLU B CA  1 
ATOM   4278  C C   . GLU B 1 117 ? 2.908   3.900   -8.194  1.00 49.29  ? 117 GLU B C   1 
ATOM   4279  O O   . GLU B 1 117 ? 2.094   4.276   -7.348  1.00 55.80  ? 117 GLU B O   1 
ATOM   4280  C CB  . GLU B 1 117 ? 2.205   2.781   -10.257 1.00 54.30  ? 117 GLU B CB  1 
ATOM   4281  C CG  . GLU B 1 117 ? 0.911   2.901   -11.024 1.00 74.43  ? 117 GLU B CG  1 
ATOM   4282  C CD  . GLU B 1 117 ? 0.501   1.650   -11.786 1.00 108.57 ? 117 GLU B CD  1 
ATOM   4283  O OE1 . GLU B 1 117 ? 1.023   1.366   -12.933 1.00 112.76 ? 117 GLU B OE1 1 
ATOM   4284  O OE2 . GLU B 1 117 ? -0.409  0.987   -11.257 1.00 134.01 ? 117 GLU B OE2 1 
ATOM   4285  N N   . SER B 1 118 ? 4.064   3.279   -7.915  1.00 44.64  ? 118 SER B N   1 
ATOM   4286  C CA  . SER B 1 118 ? 4.487   2.907   -6.584  1.00 41.55  ? 118 SER B CA  1 
ATOM   4287  C C   . SER B 1 118 ? 4.576   4.133   -5.694  1.00 39.89  ? 118 SER B C   1 
ATOM   4288  O O   . SER B 1 118 ? 4.502   4.009   -4.472  1.00 40.60  ? 118 SER B O   1 
ATOM   4289  C CB  . SER B 1 118 ? 5.831   2.185   -6.630  1.00 37.28  ? 118 SER B CB  1 
ATOM   4290  O OG  . SER B 1 118 ? 5.770   1.026   -7.449  1.00 42.59  ? 118 SER B OG  1 
ATOM   4291  N N   . ALA B 1 119 ? 4.832   5.307   -6.306  1.00 38.68  ? 119 ALA B N   1 
ATOM   4292  C CA  . ALA B 1 119 ? 4.978   6.535   -5.546  1.00 41.45  ? 119 ALA B CA  1 
ATOM   4293  C C   . ALA B 1 119 ? 3.684   6.856   -4.805  1.00 42.59  ? 119 ALA B C   1 
ATOM   4294  O O   . ALA B 1 119 ? 3.727   7.476   -3.756  1.00 44.26  ? 119 ALA B O   1 
ATOM   4295  C CB  . ALA B 1 119 ? 5.384   7.657   -6.437  1.00 44.13  ? 119 ALA B CB  1 
ATOM   4296  N N   . SER B 1 120 ? 2.544   6.385   -5.346  1.00 47.37  ? 120 SER B N   1 
ATOM   4297  C CA  . SER B 1 120 ? 1.222   6.701   -4.801  1.00 52.25  ? 120 SER B CA  1 
ATOM   4298  C C   . SER B 1 120 ? 0.816   5.708   -3.695  1.00 48.85  ? 120 SER B C   1 
ATOM   4299  O O   . SER B 1 120 ? -0.079  5.991   -2.918  1.00 55.00  ? 120 SER B O   1 
ATOM   4300  C CB  . SER B 1 120 ? 0.174   6.732   -5.898  1.00 53.11  ? 120 SER B CB  1 
ATOM   4301  O OG  . SER B 1 120 ? -0.101  5.419   -6.378  1.00 57.14  ? 120 SER B OG  1 
ATOM   4302  N N   . PHE B 1 121 ? 1.488   4.561   -3.625  1.00 46.16  ? 121 PHE B N   1 
ATOM   4303  C CA  . PHE B 1 121 ? 1.029   3.460   -2.788  1.00 46.20  ? 121 PHE B CA  1 
ATOM   4304  C C   . PHE B 1 121 ? 1.072   3.828   -1.300  1.00 44.13  ? 121 PHE B C   1 
ATOM   4305  O O   . PHE B 1 121 ? 0.183   3.440   -0.573  1.00 49.94  ? 121 PHE B O   1 
ATOM   4306  C CB  . PHE B 1 121 ? 1.824   2.180   -3.039  1.00 44.80  ? 121 PHE B CB  1 
ATOM   4307  C CG  . PHE B 1 121 ? 1.531   1.524   -4.365  1.00 41.89  ? 121 PHE B CG  1 
ATOM   4308  C CD1 . PHE B 1 121 ? 0.499   1.983   -5.175  1.00 46.71  ? 121 PHE B CD1 1 
ATOM   4309  C CD2 . PHE B 1 121 ? 2.282   0.438   -4.802  1.00 41.92  ? 121 PHE B CD2 1 
ATOM   4310  C CE1 . PHE B 1 121 ? 0.247   1.385   -6.411  1.00 51.89  ? 121 PHE B CE1 1 
ATOM   4311  C CE2 . PHE B 1 121 ? 2.022   -0.159  -6.032  1.00 45.85  ? 121 PHE B CE2 1 
ATOM   4312  C CZ  . PHE B 1 121 ? 1.001   0.306   -6.829  1.00 47.61  ? 121 PHE B CZ  1 
ATOM   4313  N N   . PRO B 1 122 ? 2.139   4.463   -0.760  1.00 41.41  ? 122 PRO B N   1 
ATOM   4314  C CA  . PRO B 1 122 ? 2.239   4.651   0.692   1.00 43.92  ? 122 PRO B CA  1 
ATOM   4315  C C   . PRO B 1 122 ? 1.002   5.306   1.326   1.00 43.60  ? 122 PRO B C   1 
ATOM   4316  O O   . PRO B 1 122 ? 0.651   5.009   2.467   1.00 49.94  ? 122 PRO B O   1 
ATOM   4317  C CB  . PRO B 1 122 ? 3.502   5.528   0.844   1.00 41.61  ? 122 PRO B CB  1 
ATOM   4318  C CG  . PRO B 1 122 ? 4.326   5.195   -0.338  1.00 40.20  ? 122 PRO B CG  1 
ATOM   4319  C CD  . PRO B 1 122 ? 3.322   4.940   -1.471  1.00 39.38  ? 122 PRO B CD  1 
ATOM   4320  N N   . ALA B 1 123 ? 0.360   6.203   0.583   1.00 42.01  ? 123 ALA B N   1 
ATOM   4321  C CA  . ALA B 1 123 ? -0.726  7.000   1.124   1.00 42.95  ? 123 ALA B CA  1 
ATOM   4322  C C   . ALA B 1 123 ? -2.004  6.173   1.218   1.00 40.24  ? 123 ALA B C   1 
ATOM   4323  O O   . ALA B 1 123 ? -2.904  6.557   1.919   1.00 44.84  ? 123 ALA B O   1 
ATOM   4324  C CB  . ALA B 1 123 ? -0.941  8.248   0.285   1.00 45.27  ? 123 ALA B CB  1 
ATOM   4325  N N   . ARG B 1 124 ? -2.056  5.016   0.538   1.00 39.03  ? 124 ARG B N   1 
ATOM   4326  C CA  . ARG B 1 124 ? -3.292  4.225   0.448   1.00 37.79  ? 124 ARG B CA  1 
ATOM   4327  C C   . ARG B 1 124 ? -3.346  3.133   1.526   1.00 42.34  ? 124 ARG B C   1 
ATOM   4328  O O   . ARG B 1 124 ? -4.383  2.492   1.706   1.00 53.26  ? 124 ARG B O   1 
ATOM   4329  C CB  . ARG B 1 124 ? -3.416  3.592   -0.937  1.00 41.61  ? 124 ARG B CB  1 
ATOM   4330  C CG  . ARG B 1 124 ? -3.596  4.624   -2.037  1.00 46.49  ? 124 ARG B CG  1 
ATOM   4331  C CD  . ARG B 1 124 ? -3.322  4.079   -3.419  1.00 49.31  ? 124 ARG B CD  1 
ATOM   4332  N NE  . ARG B 1 124 ? -4.059  2.852   -3.722  1.00 53.02  ? 124 ARG B NE  1 
ATOM   4333  C CZ  . ARG B 1 124 ? -3.942  2.178   -4.867  1.00 57.00  ? 124 ARG B CZ  1 
ATOM   4334  N NH1 . ARG B 1 124 ? -3.222  2.698   -5.867  1.00 49.69  ? 124 ARG B NH1 1 
ATOM   4335  N NH2 . ARG B 1 124 ? -4.562  0.997   -5.014  1.00 59.26  ? 124 ARG B NH2 1 
ATOM   4336  N N   . VAL B 1 125 ? -2.262  2.940   2.257   1.00 39.63  ? 125 VAL B N   1 
ATOM   4337  C CA  . VAL B 1 125 ? -2.174  1.821   3.178   1.00 47.45  ? 125 VAL B CA  1 
ATOM   4338  C C   . VAL B 1 125 ? -3.041  2.117   4.434   1.00 47.51  ? 125 VAL B C   1 
ATOM   4339  O O   . VAL B 1 125 ? -2.964  3.188   5.009   1.00 44.37  ? 125 VAL B O   1 
ATOM   4340  C CB  . VAL B 1 125 ? -0.674  1.553   3.491   1.00 53.98  ? 125 VAL B CB  1 
ATOM   4341  C CG1 . VAL B 1 125 ? -0.254  2.087   4.832   1.00 60.12  ? 125 VAL B CG1 1 
ATOM   4342  C CG2 . VAL B 1 125 ? -0.316  0.075   3.376   1.00 62.53  ? 125 VAL B CG2 1 
ATOM   4343  N N   . HIS B 1 126 ? -3.921  1.179   4.794   1.00 49.15  ? 126 HIS B N   1 
ATOM   4344  C CA  . HIS B 1 126 ? -4.884  1.509   5.880   1.00 53.95  ? 126 HIS B CA  1 
ATOM   4345  C C   . HIS B 1 126 ? -5.063  0.433   6.950   1.00 45.06  ? 126 HIS B C   1 
ATOM   4346  O O   . HIS B 1 126 ? -5.310  -0.738  6.604   1.00 44.06  ? 126 HIS B O   1 
ATOM   4347  C CB  . HIS B 1 126 ? -6.276  1.762   5.289   1.00 62.77  ? 126 HIS B CB  1 
ATOM   4348  C CG  . HIS B 1 126 ? -6.456  3.111   4.684   1.00 74.49  ? 126 HIS B CG  1 
ATOM   4349  N ND1 . HIS B 1 126 ? -7.268  3.328   3.593   1.00 84.21  ? 126 HIS B ND1 1 
ATOM   4350  C CD2 . HIS B 1 126 ? -5.943  4.302   5.008   1.00 94.95  ? 126 HIS B CD2 1 
ATOM   4351  C CE1 . HIS B 1 126 ? -7.237  4.614   3.276   1.00 93.10  ? 126 HIS B CE1 1 
ATOM   4352  N NE2 . HIS B 1 126 ? -6.437  5.224   4.123   1.00 92.04  ? 126 HIS B NE2 1 
ATOM   4353  N N   . GLY B 1 127 ? -4.897  0.815   8.216   1.00 40.75  ? 127 GLY B N   1 
ATOM   4354  C CA  . GLY B 1 127 ? -5.216  -0.068  9.354   1.00 40.13  ? 127 GLY B CA  1 
ATOM   4355  C C   . GLY B 1 127 ? -6.718  -0.065  9.594   1.00 40.92  ? 127 GLY B C   1 
ATOM   4356  O O   . GLY B 1 127 ? -7.402  0.806   9.023   1.00 37.99  ? 127 GLY B O   1 
ATOM   4357  N N   . ARG B 1 128 ? -7.231  -1.024  10.365  1.00 41.18  ? 128 ARG B N   1 
ATOM   4358  C CA  . ARG B 1 128 ? -8.693  -1.106  10.619  1.00 46.17  ? 128 ARG B CA  1 
ATOM   4359  C C   . ARG B 1 128 ? -8.993  -1.136  12.130  1.00 45.62  ? 128 ARG B C   1 
ATOM   4360  O O   . ARG B 1 128 ? -8.148  -1.637  12.897  1.00 51.05  ? 128 ARG B O   1 
ATOM   4361  C CB  . ARG B 1 128 ? -9.287  -2.342  9.940   1.00 50.00  ? 128 ARG B CB  1 
ATOM   4362  C CG  . ARG B 1 128 ? -8.388  -3.568  9.989   1.00 50.00  ? 128 ARG B CG  1 
ATOM   4363  C CD  . ARG B 1 128 ? -8.957  -4.783  9.273   1.00 50.00  ? 128 ARG B CD  1 
ATOM   4364  N NE  . ARG B 1 128 ? -8.288  -5.030  7.999   1.00 50.00  ? 128 ARG B NE  1 
ATOM   4365  C CZ  . ARG B 1 128 ? -8.512  -6.088  7.234   1.00 50.00  ? 128 ARG B CZ  1 
ATOM   4366  N NH1 . ARG B 1 128 ? -9.394  -7.006  7.608   1.00 50.00  ? 128 ARG B NH1 1 
ATOM   4367  N NH2 . ARG B 1 128 ? -7.857  -6.233  6.089   1.00 50.00  ? 128 ARG B NH2 1 
ATOM   4368  N N   . ILE B 1 129 ? -10.131 -0.565  12.539  1.00 43.05  ? 129 ILE B N   1 
ATOM   4369  C CA  . ILE B 1 129 ? -10.556 -0.599  13.971  1.00 44.58  ? 129 ILE B CA  1 
ATOM   4370  C C   . ILE B 1 129 ? -11.805 -1.488  14.054  1.00 42.61  ? 129 ILE B C   1 
ATOM   4371  O O   . ILE B 1 129 ? -12.743 -1.249  13.272  1.00 47.95  ? 129 ILE B O   1 
ATOM   4372  C CB  . ILE B 1 129 ? -10.836 0.819   14.498  1.00 48.85  ? 129 ILE B CB  1 
ATOM   4373  C CG1 . ILE B 1 129 ? -9.741  1.803   14.091  1.00 50.13  ? 129 ILE B CG1 1 
ATOM   4374  C CG2 . ILE B 1 129 ? -11.051 0.806   16.012  1.00 49.36  ? 129 ILE B CG2 1 
ATOM   4375  C CD1 . ILE B 1 129 ? -9.849  3.158   14.765  1.00 48.72  ? 129 ILE B CD1 1 
ATOM   4376  N N   . VAL B 1 130 ? -11.815 -2.473  14.958  1.00 47.59  ? 130 VAL B N   1 
ATOM   4377  C CA  . VAL B 1 130 ? -12.946 -3.450  14.999  1.00 52.17  ? 130 VAL B CA  1 
ATOM   4378  C C   . VAL B 1 130 ? -13.625 -3.469  16.377  1.00 59.08  ? 130 VAL B C   1 
ATOM   4379  O O   . VAL B 1 130 ? -12.927 -3.227  17.382  1.00 68.68  ? 130 VAL B O   1 
ATOM   4380  C CB  . VAL B 1 130 ? -12.466 -4.867  14.626  1.00 48.69  ? 130 VAL B CB  1 
ATOM   4381  C CG1 . VAL B 1 130 ? -13.553 -5.673  13.925  1.00 48.67  ? 130 VAL B CG1 1 
ATOM   4382  C CG2 . VAL B 1 130 ? -11.187 -4.850  13.800  1.00 46.55  ? 130 VAL B CG2 1 
ATOM   4383  N N   . GLU B 1 131 ? -14.932 -3.749  16.413  1.00 65.50  ? 131 GLU B N   1 
ATOM   4384  C CA  . GLU B 1 131 ? -15.676 -3.885  17.667  1.00 63.24  ? 131 GLU B CA  1 
ATOM   4385  C C   . GLU B 1 131 ? -15.482 -5.305  18.205  1.00 54.55  ? 131 GLU B C   1 
ATOM   4386  O O   . GLU B 1 131 ? -15.058 -6.195  17.475  1.00 48.33  ? 131 GLU B O   1 
ATOM   4387  C CB  . GLU B 1 131 ? -17.172 -3.608  17.455  1.00 80.77  ? 131 GLU B CB  1 
ATOM   4388  C CG  . GLU B 1 131 ? -17.485 -2.577  16.363  1.00 89.20  ? 131 GLU B CG  1 
ATOM   4389  C CD  . GLU B 1 131 ? -16.847 -1.208  16.563  1.00 99.36  ? 131 GLU B CD  1 
ATOM   4390  O OE1 . GLU B 1 131 ? -16.392 -0.577  15.543  1.00 97.46  ? 131 GLU B OE1 1 
ATOM   4391  O OE2 . GLU B 1 131 ? -16.793 -0.770  17.743  1.00 85.72  ? 131 GLU B OE2 1 
ATOM   4392  N N   . SER B 1 132 ? -15.808 -5.514  19.479  1.00 50.52  ? 132 SER B N   1 
ATOM   4393  C CA  . SER B 1 132 ? -15.591 -6.809  20.112  1.00 52.23  ? 132 SER B CA  1 
ATOM   4394  C C   . SER B 1 132 ? -16.827 -7.223  20.918  1.00 54.39  ? 132 SER B C   1 
ATOM   4395  O O   . SER B 1 132 ? -17.500 -6.386  21.503  1.00 51.98  ? 132 SER B O   1 
ATOM   4396  C CB  . SER B 1 132 ? -14.347 -6.784  20.991  1.00 50.92  ? 132 SER B CB  1 
ATOM   4397  O OG  . SER B 1 132 ? -14.303 -7.930  21.835  1.00 47.47  ? 132 SER B OG  1 
ATOM   4398  N N   . ASP B 1 133 ? -17.065 -8.538  21.013  1.00 50.02  ? 133 ASP B N   1 
ATOM   4399  C CA  . ASP B 1 133 ? -18.151 -9.038  21.827  1.00 50.58  ? 133 ASP B CA  1 
ATOM   4400  C C   . ASP B 1 133 ? -17.778 -8.976  23.300  1.00 53.63  ? 133 ASP B C   1 
ATOM   4401  O O   . ASP B 1 133 ? -18.660 -8.915  24.152  1.00 53.96  ? 133 ASP B O   1 
ATOM   4402  C CB  . ASP B 1 133 ? -18.577 -10.427 21.417  1.00 52.60  ? 133 ASP B CB  1 
ATOM   4403  C CG  . ASP B 1 133 ? -19.715 -10.466 20.408  1.00 53.39  ? 133 ASP B CG  1 
ATOM   4404  O OD1 . ASP B 1 133 ? -20.749 -9.757  20.641  1.00 65.02  ? 133 ASP B OD1 1 
ATOM   4405  O OD2 . ASP B 1 133 ? -19.576 -11.185 19.413  1.00 46.77  ? 133 ASP B OD2 1 
ATOM   4406  N N   . VAL B 1 134 ? -16.474 -8.981  23.595  1.00 50.41  ? 134 VAL B N   1 
ATOM   4407  C CA  . VAL B 1 134 ? -16.006 -8.867  24.972  1.00 52.85  ? 134 VAL B CA  1 
ATOM   4408  C C   . VAL B 1 134 ? -16.219 -7.433  25.450  1.00 48.56  ? 134 VAL B C   1 
ATOM   4409  O O   . VAL B 1 134 ? -15.779 -6.487  24.804  1.00 56.28  ? 134 VAL B O   1 
ATOM   4410  C CB  . VAL B 1 134 ? -14.531 -9.283  25.106  1.00 62.55  ? 134 VAL B CB  1 
ATOM   4411  C CG1 . VAL B 1 134 ? -14.163 -9.571  26.562  1.00 63.05  ? 134 VAL B CG1 1 
ATOM   4412  C CG2 . VAL B 1 134 ? -14.192 -10.490 24.215  1.00 58.47  ? 134 VAL B CG2 1 
ATOM   4413  N N   . PRO B 1 135 ? -16.911 -7.217  26.582  1.00 48.75  ? 135 PRO B N   1 
ATOM   4414  C CA  . PRO B 1 135 ? -17.057 -5.868  27.141  1.00 46.52  ? 135 PRO B CA  1 
ATOM   4415  C C   . PRO B 1 135 ? -15.712 -5.248  27.482  1.00 44.33  ? 135 PRO B C   1 
ATOM   4416  O O   . PRO B 1 135 ? -14.901 -5.875  28.140  1.00 49.68  ? 135 PRO B O   1 
ATOM   4417  C CB  . PRO B 1 135 ? -17.935 -6.077  28.409  1.00 46.68  ? 135 PRO B CB  1 
ATOM   4418  C CG  . PRO B 1 135 ? -18.597 -7.445  28.186  1.00 49.06  ? 135 PRO B CG  1 
ATOM   4419  C CD  . PRO B 1 135 ? -17.600 -8.241  27.374  1.00 48.50  ? 135 PRO B CD  1 
ATOM   4420  N N   . GLY B 1 136 ? -15.504 -3.999  27.032  1.00 46.65  ? 136 GLY B N   1 
ATOM   4421  C CA  . GLY B 1 136 ? -14.320 -3.221  27.373  1.00 43.56  ? 136 GLY B CA  1 
ATOM   4422  C C   . GLY B 1 136 ? -13.109 -3.551  26.468  1.00 45.30  ? 136 GLY B C   1 
ATOM   4423  O O   . GLY B 1 136 ? -12.009 -3.096  26.734  1.00 49.84  ? 136 GLY B O   1 
ATOM   4424  N N   . LYS B 1 137 ? -13.322 -4.337  25.400  1.00 41.95  ? 137 LYS B N   1 
ATOM   4425  C CA  . LYS B 1 137 ? -12.244 -4.696  24.485  1.00 40.69  ? 137 LYS B CA  1 
ATOM   4426  C C   . LYS B 1 137 ? -12.417 -3.942  23.162  1.00 39.09  ? 137 LYS B C   1 
ATOM   4427  O O   . LYS B 1 137 ? -13.507 -3.887  22.628  1.00 42.08  ? 137 LYS B O   1 
ATOM   4428  C CB  . LYS B 1 137 ? -12.232 -6.198  24.244  1.00 42.52  ? 137 LYS B CB  1 
ATOM   4429  C CG  . LYS B 1 137 ? -11.082 -6.681  23.375  1.00 50.33  ? 137 LYS B CG  1 
ATOM   4430  C CD  . LYS B 1 137 ? -11.160 -8.156  22.951  1.00 56.34  ? 137 LYS B CD  1 
ATOM   4431  C CE  . LYS B 1 137 ? -10.802 -9.172  24.053  1.00 59.08  ? 137 LYS B CE  1 
ATOM   4432  N NZ  . LYS B 1 137 ? -9.630  -8.768  24.843  1.00 60.36  ? 137 LYS B NZ  1 
ATOM   4433  N N   . GLU B 1 138 ? -11.327 -3.327  22.681  1.00 43.42  ? 138 GLU B N   1 
ATOM   4434  C CA  . GLU B 1 138 ? -11.273 -2.728  21.347  1.00 46.81  ? 138 GLU B CA  1 
ATOM   4435  C C   . GLU B 1 138 ? -10.131 -3.378  20.560  1.00 42.10  ? 138 GLU B C   1 
ATOM   4436  O O   . GLU B 1 138 ? -9.056  -3.615  21.107  1.00 41.21  ? 138 GLU B O   1 
ATOM   4437  C CB  . GLU B 1 138 ? -11.077 -1.201  21.410  1.00 58.73  ? 138 GLU B CB  1 
ATOM   4438  C CG  . GLU B 1 138 ? -9.613  -0.749  21.483  1.00 65.45  ? 138 GLU B CG  1 
ATOM   4439  C CD  . GLU B 1 138 ? -9.378  0.654   20.927  1.00 75.37  ? 138 GLU B CD  1 
ATOM   4440  O OE1 . GLU B 1 138 ? -9.441  0.852   19.677  1.00 76.61  ? 138 GLU B OE1 1 
ATOM   4441  O OE2 . GLU B 1 138 ? -9.142  1.555   21.750  1.00 81.83  ? 138 GLU B OE2 1 
ATOM   4442  N N   . SER B 1 139 ? -10.379 -3.653  19.274  1.00 36.83  ? 139 SER B N   1 
ATOM   4443  C CA  . SER B 1 139 ? -9.383  -4.249  18.397  1.00 38.59  ? 139 SER B CA  1 
ATOM   4444  C C   . SER B 1 139 ? -8.865  -3.205  17.426  1.00 44.59  ? 139 SER B C   1 
ATOM   4445  O O   . SER B 1 139 ? -9.639  -2.624  16.671  1.00 51.79  ? 139 SER B O   1 
ATOM   4446  C CB  . SER B 1 139 ? -9.936  -5.409  17.663  1.00 41.25  ? 139 SER B CB  1 
ATOM   4447  O OG  . SER B 1 139 ? -9.898  -6.581  18.454  1.00 47.40  ? 139 SER B OG  1 
ATOM   4448  N N   . ARG B 1 140 ? -7.545  -2.959  17.470  1.00 44.39  ? 140 ARG B N   1 
ATOM   4449  C CA  . ARG B 1 140 ? -6.868  -2.169  16.457  1.00 45.33  ? 140 ARG B CA  1 
ATOM   4450  C C   . ARG B 1 140 ? -6.000  -3.096  15.602  1.00 43.76  ? 140 ARG B C   1 
ATOM   4451  O O   . ARG B 1 140 ? -5.221  -3.876  16.132  1.00 52.09  ? 140 ARG B O   1 
ATOM   4452  C CB  . ARG B 1 140 ? -6.035  -1.073  17.123  1.00 48.07  ? 140 ARG B CB  1 
ATOM   4453  C CG  . ARG B 1 140 ? -6.859  -0.024  17.859  1.00 57.09  ? 140 ARG B CG  1 
ATOM   4454  C CD  . ARG B 1 140 ? -6.077  1.259   18.140  1.00 57.64  ? 140 ARG B CD  1 
ATOM   4455  N NE  . ARG B 1 140 ? -6.352  1.764   19.489  1.00 62.39  ? 140 ARG B NE  1 
ATOM   4456  C CZ  . ARG B 1 140 ? -5.479  1.769   20.490  1.00 53.85  ? 140 ARG B CZ  1 
ATOM   4457  N NH1 . ARG B 1 140 ? -4.236  1.505   20.253  1.00 58.11  ? 140 ARG B NH1 1 
ATOM   4458  N NH2 . ARG B 1 140 ? -5.849  2.069   21.721  1.00 51.70  ? 140 ARG B NH2 1 
ATOM   4459  N N   . VAL B 1 141 ? -6.147  -3.001  14.277  1.00 38.06  ? 141 VAL B N   1 
ATOM   4460  C CA  . VAL B 1 141 ? -5.261  -3.698  13.354  1.00 35.02  ? 141 VAL B CA  1 
ATOM   4461  C C   . VAL B 1 141 ? -4.377  -2.680  12.631  1.00 35.47  ? 141 VAL B C   1 
ATOM   4462  O O   . VAL B 1 141 ? -4.873  -1.833  11.917  1.00 38.87  ? 141 VAL B O   1 
ATOM   4463  C CB  . VAL B 1 141 ? -6.081  -4.532  12.377  1.00 34.61  ? 141 VAL B CB  1 
ATOM   4464  C CG1 . VAL B 1 141 ? -5.244  -5.591  11.694  1.00 33.61  ? 141 VAL B CG1 1 
ATOM   4465  C CG2 . VAL B 1 141 ? -7.270  -5.178  13.079  1.00 40.89  ? 141 VAL B CG2 1 
ATOM   4466  N N   . TYR B 1 142 ? -3.054  -2.811  12.806  1.00 36.41  ? 142 TYR B N   1 
ATOM   4467  C CA  . TYR B 1 142 ? -2.074  -1.957  12.132  1.00 38.35  ? 142 TYR B CA  1 
ATOM   4468  C C   . TYR B 1 142 ? -1.507  -2.686  10.901  1.00 39.42  ? 142 TYR B C   1 
ATOM   4469  O O   . TYR B 1 142 ? -1.227  -3.878  10.963  1.00 35.03  ? 142 TYR B O   1 
ATOM   4470  C CB  . TYR B 1 142 ? -0.956  -1.581  13.116  1.00 39.37  ? 142 TYR B CB  1 
ATOM   4471  C CG  . TYR B 1 142 ? -1.406  -0.721  14.309  1.00 39.89  ? 142 TYR B CG  1 
ATOM   4472  C CD1 . TYR B 1 142 ? -1.470  0.655   14.215  1.00 40.52  ? 142 TYR B CD1 1 
ATOM   4473  C CD2 . TYR B 1 142 ? -1.780  -1.297  15.516  1.00 42.33  ? 142 TYR B CD2 1 
ATOM   4474  C CE1 . TYR B 1 142 ? -1.891  1.434   15.278  1.00 39.56  ? 142 TYR B CE1 1 
ATOM   4475  C CE2 . TYR B 1 142 ? -2.182  -0.528  16.591  1.00 38.12  ? 142 TYR B CE2 1 
ATOM   4476  C CZ  . TYR B 1 142 ? -2.254  0.838   16.464  1.00 39.56  ? 142 TYR B CZ  1 
ATOM   4477  O OH  . TYR B 1 142 ? -2.661  1.598   17.508  1.00 41.01  ? 142 TYR B OH  1 
ATOM   4478  N N   . ARG B 1 143 ? -1.413  -1.960  9.769   1.00 38.60  ? 143 ARG B N   1 
ATOM   4479  C CA  . ARG B 1 143 ? -0.801  -2.469  8.549   1.00 44.96  ? 143 ARG B CA  1 
ATOM   4480  C C   . ARG B 1 143 ? 0.629   -1.929  8.447   1.00 45.23  ? 143 ARG B C   1 
ATOM   4481  O O   . ARG B 1 143 ? 0.829   -0.722  8.327   1.00 53.33  ? 143 ARG B O   1 
ATOM   4482  C CB  . ARG B 1 143 ? -1.607  -2.002  7.334   1.00 49.17  ? 143 ARG B CB  1 
ATOM   4483  C CG  . ARG B 1 143 ? -1.509  -2.873  6.091   1.00 52.84  ? 143 ARG B CG  1 
ATOM   4484  C CD  . ARG B 1 143 ? -2.466  -4.023  6.191   1.00 56.24  ? 143 ARG B CD  1 
ATOM   4485  N NE  . ARG B 1 143 ? -2.574  -4.768  4.939   1.00 56.06  ? 143 ARG B NE  1 
ATOM   4486  C CZ  . ARG B 1 143 ? -2.400  -6.080  4.823   1.00 58.00  ? 143 ARG B CZ  1 
ATOM   4487  N NH1 . ARG B 1 143 ? -2.413  -6.847  5.877   1.00 70.69  ? 143 ARG B NH1 1 
ATOM   4488  N NH2 . ARG B 1 143 ? -2.309  -6.625  3.648   1.00 62.40  ? 143 ARG B NH2 1 
ATOM   4489  N N   . SER B 1 144 ? 1.616   -2.822  8.474   1.00 44.70  ? 144 SER B N   1 
ATOM   4490  C CA  . SER B 1 144 ? 3.021   -2.398  8.438   1.00 49.01  ? 144 SER B CA  1 
ATOM   4491  C C   . SER B 1 144 ? 3.799   -3.202  7.413   1.00 45.18  ? 144 SER B C   1 
ATOM   4492  O O   . SER B 1 144 ? 3.381   -4.287  7.026   1.00 52.23  ? 144 SER B O   1 
ATOM   4493  C CB  . SER B 1 144 ? 3.667   -2.512  9.791   1.00 47.47  ? 144 SER B CB  1 
ATOM   4494  O OG  . SER B 1 144 ? 2.977   -1.712  10.731  1.00 56.63  ? 144 SER B OG  1 
ATOM   4495  N N   . ALA B 1 145 ? 4.983   -2.683  7.060   1.00 45.64  ? 145 ALA B N   1 
ATOM   4496  C CA  . ALA B 1 145 ? 5.902   -3.356  6.157   1.00 41.45  ? 145 ALA B CA  1 
ATOM   4497  C C   . ALA B 1 145 ? 6.344   -4.687  6.747   1.00 39.56  ? 145 ALA B C   1 
ATOM   4498  O O   . ALA B 1 145 ? 6.463   -4.830  7.955   1.00 41.60  ? 145 ALA B O   1 
ATOM   4499  C CB  . ALA B 1 145 ? 7.071   -2.486  5.886   1.00 42.60  ? 145 ALA B CB  1 
ATOM   4500  N N   . ILE B 1 146 ? 6.596   -5.646  5.868   1.00 37.51  ? 146 ILE B N   1 
ATOM   4501  C CA  . ILE B 1 146 ? 7.003   -6.972  6.271   1.00 39.74  ? 146 ILE B CA  1 
ATOM   4502  C C   . ILE B 1 146 ? 8.313   -6.882  7.073   1.00 40.17  ? 146 ILE B C   1 
ATOM   4503  O O   . ILE B 1 146 ? 8.461   -7.556  8.113   1.00 39.98  ? 146 ILE B O   1 
ATOM   4504  C CB  . ILE B 1 146 ? 7.133   -7.884  5.036   1.00 38.81  ? 146 ILE B CB  1 
ATOM   4505  C CG1 . ILE B 1 146 ? 5.803   -8.035  4.340   1.00 41.44  ? 146 ILE B CG1 1 
ATOM   4506  C CG2 . ILE B 1 146 ? 7.735   -9.236  5.412   1.00 40.20  ? 146 ILE B CG2 1 
ATOM   4507  C CD1 . ILE B 1 146 ? 5.733   -9.191  3.374   1.00 44.97  ? 146 ILE B CD1 1 
ATOM   4508  N N   . GLY B 1 147 ? 9.251   -6.064  6.572   1.00 38.48  ? 147 GLY B N   1 
ATOM   4509  C CA  . GLY B 1 147 ? 10.605  -5.971  7.117   1.00 38.49  ? 147 GLY B CA  1 
ATOM   4510  C C   . GLY B 1 147 ? 11.650  -5.971  5.985   1.00 38.10  ? 147 GLY B C   1 
ATOM   4511  O O   . GLY B 1 147 ? 11.909  -4.945  5.356   1.00 34.61  ? 147 GLY B O   1 
ATOM   4512  N N   . VAL B 1 148 ? 12.200  -7.146  5.712   1.00 38.91  ? 148 VAL B N   1 
ATOM   4513  C CA  . VAL B 1 148 ? 13.189  -7.319  4.670   1.00 39.58  ? 148 VAL B CA  1 
ATOM   4514  C C   . VAL B 1 148 ? 12.625  -8.265  3.642   1.00 35.48  ? 148 VAL B C   1 
ATOM   4515  O O   . VAL B 1 148 ? 12.124  -9.322  4.000   1.00 38.62  ? 148 VAL B O   1 
ATOM   4516  C CB  . VAL B 1 148 ? 14.516  -7.859  5.226   1.00 44.81  ? 148 VAL B CB  1 
ATOM   4517  C CG1 . VAL B 1 148 ? 15.486  -8.250  4.103   1.00 44.79  ? 148 VAL B CG1 1 
ATOM   4518  C CG2 . VAL B 1 148 ? 15.159  -6.875  6.205   1.00 43.45  ? 148 VAL B CG2 1 
ATOM   4519  N N   . VAL B 1 149 ? 12.727  -7.875  2.360   1.00 34.13  ? 149 VAL B N   1 
ATOM   4520  C CA  . VAL B 1 149 ? 12.285  -8.716  1.260   1.00 38.97  ? 149 VAL B CA  1 
ATOM   4521  C C   . VAL B 1 149 ? 13.508  -9.153  0.447   1.00 40.58  ? 149 VAL B C   1 
ATOM   4522  O O   . VAL B 1 149 ? 14.328  -8.330  0.070   1.00 38.27  ? 149 VAL B O   1 
ATOM   4523  C CB  . VAL B 1 149 ? 11.258  -7.995  0.369   1.00 38.02  ? 149 VAL B CB  1 
ATOM   4524  C CG1 . VAL B 1 149 ? 10.696  -8.929  -0.698  1.00 38.65  ? 149 VAL B CG1 1 
ATOM   4525  C CG2 . VAL B 1 149 ? 10.140  -7.394  1.186   1.00 37.48  ? 149 VAL B CG2 1 
ATOM   4526  N N   . GLY B 1 150 ? 13.608  -10.457 0.197   1.00 38.50  ? 150 GLY B N   1 
ATOM   4527  C CA  . GLY B 1 150 ? 14.646  -11.004 -0.649  1.00 38.08  ? 150 GLY B CA  1 
ATOM   4528  C C   . GLY B 1 150 ? 14.099  -11.311 -2.030  1.00 39.05  ? 150 GLY B C   1 
ATOM   4529  O O   . GLY B 1 150 ? 13.121  -12.034 -2.152  1.00 35.94  ? 150 GLY B O   1 
ATOM   4530  N N   . VAL B 1 151 ? 14.724  -10.707 -3.061  1.00 41.90  ? 151 VAL B N   1 
ATOM   4531  C CA  . VAL B 1 151 ? 14.230  -10.759 -4.433  1.00 41.23  ? 151 VAL B CA  1 
ATOM   4532  C C   . VAL B 1 151 ? 15.257  -11.472 -5.300  1.00 41.90  ? 151 VAL B C   1 
ATOM   4533  O O   . VAL B 1 151 ? 16.394  -11.018 -5.400  1.00 41.39  ? 151 VAL B O   1 
ATOM   4534  C CB  . VAL B 1 151 ? 13.964  -9.344  -4.976  1.00 39.53  ? 151 VAL B CB  1 
ATOM   4535  C CG1 . VAL B 1 151 ? 13.565  -9.373  -6.454  1.00 41.02  ? 151 VAL B CG1 1 
ATOM   4536  C CG2 . VAL B 1 151 ? 12.925  -8.612  -4.150  1.00 39.80  ? 151 VAL B CG2 1 
ATOM   4537  N N   . ILE B 1 152 ? 14.837  -12.573 -5.947  1.00 41.89  ? 152 ILE B N   1 
ATOM   4538  C CA  . ILE B 1 152 ? 15.665  -13.243 -6.944  1.00 41.35  ? 152 ILE B CA  1 
ATOM   4539  C C   . ILE B 1 152 ? 15.198  -12.834 -8.343  1.00 35.40  ? 152 ILE B C   1 
ATOM   4540  O O   . ILE B 1 152 ? 14.051  -13.021 -8.682  1.00 39.06  ? 152 ILE B O   1 
ATOM   4541  C CB  . ILE B 1 152 ? 15.627  -14.756 -6.753  1.00 43.40  ? 152 ILE B CB  1 
ATOM   4542  C CG1 . ILE B 1 152 ? 16.051  -15.144 -5.352  1.00 44.10  ? 152 ILE B CG1 1 
ATOM   4543  C CG2 . ILE B 1 152 ? 16.476  -15.465 -7.816  1.00 42.94  ? 152 ILE B CG2 1 
ATOM   4544  C CD1 . ILE B 1 152 ? 15.314  -16.341 -4.808  1.00 44.76  ? 152 ILE B CD1 1 
ATOM   4545  N N   . SER B 1 153 ? 16.131  -12.285 -9.136  1.00 37.70  ? 153 SER B N   1 
ATOM   4546  C CA  . SER B 1 153 ? 15.842  -11.721 -10.459 1.00 39.77  ? 153 SER B CA  1 
ATOM   4547  C C   . SER B 1 153 ? 16.126  -12.765 -11.522 1.00 38.60  ? 153 SER B C   1 
ATOM   4548  O O   . SER B 1 153 ? 17.111  -13.478 -11.433 1.00 40.98  ? 153 SER B O   1 
ATOM   4549  C CB  . SER B 1 153 ? 16.668  -10.498 -10.737 1.00 42.61  ? 153 SER B CB  1 
ATOM   4550  O OG  . SER B 1 153 ? 17.069  -9.845  -9.555  1.00 62.02  ? 153 SER B OG  1 
ATOM   4551  N N   . PRO B 1 154 ? 15.319  -12.837 -12.587 1.00 45.54  ? 154 PRO B N   1 
ATOM   4552  C CA  . PRO B 1 154 ? 15.601  -13.737 -13.707 1.00 46.60  ? 154 PRO B CA  1 
ATOM   4553  C C   . PRO B 1 154 ? 16.495  -13.089 -14.758 1.00 48.85  ? 154 PRO B C   1 
ATOM   4554  O O   . PRO B 1 154 ? 16.701  -11.859 -14.738 1.00 46.00  ? 154 PRO B O   1 
ATOM   4555  C CB  . PRO B 1 154 ? 14.189  -13.987 -14.233 1.00 43.68  ? 154 PRO B CB  1 
ATOM   4556  C CG  . PRO B 1 154 ? 13.490  -12.623 -14.046 1.00 42.67  ? 154 PRO B CG  1 
ATOM   4557  C CD  . PRO B 1 154 ? 14.075  -12.064 -12.766 1.00 42.96  ? 154 PRO B CD  1 
ATOM   4558  N N   . TRP B 1 155 ? 16.906  -13.894 -15.751 1.00 52.42  ? 155 TRP B N   1 
ATOM   4559  C CA  . TRP B 1 155 ? 17.726  -13.398 -16.852 1.00 55.27  ? 155 TRP B CA  1 
ATOM   4560  C C   . TRP B 1 155 ? 16.843  -12.810 -17.955 1.00 58.12  ? 155 TRP B C   1 
ATOM   4561  O O   . TRP B 1 155 ? 17.317  -11.995 -18.736 1.00 55.97  ? 155 TRP B O   1 
ATOM   4562  C CB  . TRP B 1 155 ? 18.641  -14.504 -17.401 1.00 53.53  ? 155 TRP B CB  1 
ATOM   4563  C CG  . TRP B 1 155 ? 17.942  -15.476 -18.300 1.00 63.23  ? 155 TRP B CG  1 
ATOM   4564  C CD1 . TRP B 1 155 ? 17.503  -15.245 -19.577 1.00 70.81  ? 155 TRP B CD1 1 
ATOM   4565  C CD2 . TRP B 1 155 ? 17.586  -16.835 -17.990 1.00 69.10  ? 155 TRP B CD2 1 
ATOM   4566  N NE1 . TRP B 1 155 ? 16.895  -16.365 -20.082 1.00 77.07  ? 155 TRP B NE1 1 
ATOM   4567  C CE2 . TRP B 1 155 ? 16.931  -17.359 -19.136 1.00 75.82  ? 155 TRP B CE2 1 
ATOM   4568  C CE3 . TRP B 1 155 ? 17.742  -17.654 -16.868 1.00 74.07  ? 155 TRP B CE3 1 
ATOM   4569  C CZ2 . TRP B 1 155 ? 16.439  -18.664 -19.180 1.00 86.11  ? 155 TRP B CZ2 1 
ATOM   4570  C CZ3 . TRP B 1 155 ? 17.255  -18.950 -16.914 1.00 85.96  ? 155 TRP B CZ3 1 
ATOM   4571  C CH2 . TRP B 1 155 ? 16.611  -19.446 -18.056 1.00 85.45  ? 155 TRP B CH2 1 
ATOM   4572  N N   . ASN B 1 156 ? 15.553  -13.224 -17.993 1.00 64.98  ? 156 ASN B N   1 
ATOM   4573  C CA  . ASN B 1 156 ? 14.643  -12.908 -19.096 1.00 72.92  ? 156 ASN B CA  1 
ATOM   4574  C C   . ASN B 1 156 ? 14.409  -11.396 -19.181 1.00 73.44  ? 156 ASN B C   1 
ATOM   4575  O O   . ASN B 1 156 ? 14.782  -10.764 -20.165 1.00 106.00 ? 156 ASN B O   1 
ATOM   4576  C CB  . ASN B 1 156 ? 13.321  -13.664 -18.972 1.00 91.31  ? 156 ASN B CB  1 
ATOM   4577  C CG  . ASN B 1 156 ? 12.182  -12.965 -19.697 1.00 112.48 ? 156 ASN B CG  1 
ATOM   4578  O OD1 . ASN B 1 156 ? 12.331  -12.566 -20.861 1.00 112.32 ? 156 ASN B OD1 1 
ATOM   4579  N ND2 . ASN B 1 156 ? 11.046  -12.796 -19.027 1.00 119.63 ? 156 ASN B ND2 1 
ATOM   4580  N N   . PHE B 1 157 ? 13.728  -10.841 -18.188 1.00 64.62  ? 157 PHE B N   1 
ATOM   4581  C CA  . PHE B 1 157 ? 13.435  -9.413  -18.171 1.00 69.72  ? 157 PHE B CA  1 
ATOM   4582  C C   . PHE B 1 157 ? 13.988  -8.824  -16.892 1.00 61.37  ? 157 PHE B C   1 
ATOM   4583  O O   . PHE B 1 157 ? 13.226  -8.451  -16.004 1.00 55.52  ? 157 PHE B O   1 
ATOM   4584  C CB  . PHE B 1 157 ? 11.934  -9.149  -18.241 1.00 83.46  ? 157 PHE B CB  1 
ATOM   4585  C CG  . PHE B 1 157 ? 11.404  -8.728  -19.594 1.00 92.48  ? 157 PHE B CG  1 
ATOM   4586  C CD1 . PHE B 1 157 ? 11.038  -9.679  -20.543 1.00 95.74  ? 157 PHE B CD1 1 
ATOM   4587  C CD2 . PHE B 1 157 ? 11.198  -7.378  -19.888 1.00 93.41  ? 157 PHE B CD2 1 
ATOM   4588  C CE1 . PHE B 1 157 ? 10.500  -9.289  -21.764 1.00 96.69  ? 157 PHE B CE1 1 
ATOM   4589  C CE2 . PHE B 1 157 ? 10.672  -6.991  -21.112 1.00 96.00  ? 157 PHE B CE2 1 
ATOM   4590  C CZ  . PHE B 1 157 ? 10.311  -7.945  -22.043 1.00 101.84 ? 157 PHE B CZ  1 
ATOM   4591  N N   . PRO B 1 158 ? 15.325  -8.747  -16.748 1.00 56.36  ? 158 PRO B N   1 
ATOM   4592  C CA  . PRO B 1 158 ? 15.941  -8.481  -15.457 1.00 51.64  ? 158 PRO B CA  1 
ATOM   4593  C C   . PRO B 1 158 ? 15.467  -7.175  -14.812 1.00 45.41  ? 158 PRO B C   1 
ATOM   4594  O O   . PRO B 1 158 ? 15.084  -7.174  -13.651 1.00 42.54  ? 158 PRO B O   1 
ATOM   4595  C CB  . PRO B 1 158 ? 17.450  -8.455  -15.799 1.00 60.52  ? 158 PRO B CB  1 
ATOM   4596  C CG  . PRO B 1 158 ? 17.547  -9.243  -17.066 1.00 64.64  ? 158 PRO B CG  1 
ATOM   4597  C CD  . PRO B 1 158 ? 16.301  -8.892  -17.821 1.00 60.55  ? 158 PRO B CD  1 
ATOM   4598  N N   . LEU B 1 159 ? 15.510  -6.061  -15.577 1.00 41.54  ? 159 LEU B N   1 
ATOM   4599  C CA  . LEU B 1 159 ? 15.308  -4.741  -15.006 1.00 37.88  ? 159 LEU B CA  1 
ATOM   4600  C C   . LEU B 1 159 ? 13.854  -4.601  -14.566 1.00 40.26  ? 159 LEU B C   1 
ATOM   4601  O O   . LEU B 1 159 ? 13.584  -4.276  -13.423 1.00 42.28  ? 159 LEU B O   1 
ATOM   4602  C CB  . LEU B 1 159 ? 15.688  -3.660  -16.007 1.00 39.04  ? 159 LEU B CB  1 
ATOM   4603  C CG  . LEU B 1 159 ? 15.572  -2.216  -15.501 1.00 40.03  ? 159 LEU B CG  1 
ATOM   4604  C CD1 . LEU B 1 159 ? 16.915  -1.648  -15.235 1.00 44.10  ? 159 LEU B CD1 1 
ATOM   4605  C CD2 . LEU B 1 159 ? 14.833  -1.336  -16.475 1.00 44.88  ? 159 LEU B CD2 1 
ATOM   4606  N N   . HIS B 1 160 ? 12.926  -4.872  -15.485 1.00 42.00  ? 160 HIS B N   1 
ATOM   4607  C CA  . HIS B 1 160 ? 11.505  -4.640  -15.236 1.00 45.92  ? 160 HIS B CA  1 
ATOM   4608  C C   . HIS B 1 160 ? 11.005  -5.537  -14.108 1.00 41.24  ? 160 HIS B C   1 
ATOM   4609  O O   . HIS B 1 160 ? 10.275  -5.081  -13.251 1.00 33.08  ? 160 HIS B O   1 
ATOM   4610  C CB  . HIS B 1 160 ? 10.671  -4.882  -16.494 1.00 49.13  ? 160 HIS B CB  1 
ATOM   4611  C CG  . HIS B 1 160 ? 9.211   -4.996  -16.209 1.00 53.60  ? 160 HIS B CG  1 
ATOM   4612  N ND1 . HIS B 1 160 ? 8.447   -6.049  -16.662 1.00 54.23  ? 160 HIS B ND1 1 
ATOM   4613  C CD2 . HIS B 1 160 ? 8.371   -4.213  -15.485 1.00 57.90  ? 160 HIS B CD2 1 
ATOM   4614  C CE1 . HIS B 1 160 ? 7.198   -5.904  -16.232 1.00 49.98  ? 160 HIS B CE1 1 
ATOM   4615  N NE2 . HIS B 1 160 ? 7.129   -4.793  -15.525 1.00 50.23  ? 160 HIS B NE2 1 
ATOM   4616  N N   . LEU B 1 161 ? 11.376  -6.829  -14.155 1.00 42.06  ? 161 LEU B N   1 
ATOM   4617  C CA  . LEU B 1 161 ? 10.863  -7.811  -13.209 1.00 43.29  ? 161 LEU B CA  1 
ATOM   4618  C C   . LEU B 1 161 ? 11.449  -7.565  -11.801 1.00 44.81  ? 161 LEU B C   1 
ATOM   4619  O O   . LEU B 1 161 ? 10.765  -7.776  -10.798 1.00 46.53  ? 161 LEU B O   1 
ATOM   4620  C CB  . LEU B 1 161 ? 11.143  -9.227  -13.710 1.00 41.20  ? 161 LEU B CB  1 
ATOM   4621  C CG  . LEU B 1 161 ? 10.258  -9.699  -14.874 1.00 45.00  ? 161 LEU B CG  1 
ATOM   4622  C CD1 . LEU B 1 161 ? 10.402  -11.197 -15.157 1.00 49.01  ? 161 LEU B CD1 1 
ATOM   4623  C CD2 . LEU B 1 161 ? 8.817   -9.370  -14.623 1.00 45.71  ? 161 LEU B CD2 1 
ATOM   4624  N N   . THR B 1 162 ? 12.688  -7.090  -11.730 1.00 39.04  ? 162 THR B N   1 
ATOM   4625  C CA  . THR B 1 162 ? 13.250  -6.703  -10.453 1.00 38.79  ? 162 THR B CA  1 
ATOM   4626  C C   . THR B 1 162 ? 12.476  -5.507  -9.908  1.00 37.20  ? 162 THR B C   1 
ATOM   4627  O O   . THR B 1 162 ? 12.114  -5.499  -8.752  1.00 35.54  ? 162 THR B O   1 
ATOM   4628  C CB  . THR B 1 162 ? 14.744  -6.394  -10.562 1.00 40.15  ? 162 THR B CB  1 
ATOM   4629  O OG1 . THR B 1 162 ? 15.406  -7.569  -11.005 1.00 36.48  ? 162 THR B OG1 1 
ATOM   4630  C CG2 . THR B 1 162 ? 15.343  -6.003  -9.227  1.00 38.47  ? 162 THR B CG2 1 
ATOM   4631  N N   . GLN B 1 163 ? 12.272  -4.472  -10.741 1.00 39.66  ? 163 GLN B N   1 
ATOM   4632  C CA  . GLN B 1 163 ? 11.664  -3.223  -10.266 1.00 38.31  ? 163 GLN B CA  1 
ATOM   4633  C C   . GLN B 1 163 ? 10.215  -3.476  -9.829  1.00 38.67  ? 163 GLN B C   1 
ATOM   4634  O O   . GLN B 1 163 ? 9.720   -2.828  -8.915  1.00 39.01  ? 163 GLN B O   1 
ATOM   4635  C CB  . GLN B 1 163 ? 11.713  -2.123  -11.327 1.00 35.59  ? 163 GLN B CB  1 
ATOM   4636  C CG  . GLN B 1 163 ? 11.349  -0.726  -10.813 1.00 30.48  ? 163 GLN B CG  1 
ATOM   4637  C CD  . GLN B 1 163 ? 12.454  -0.094  -10.012 1.00 31.08  ? 163 GLN B CD  1 
ATOM   4638  O OE1 . GLN B 1 163 ? 13.341  -0.775  -9.508  1.00 32.41  ? 163 GLN B OE1 1 
ATOM   4639  N NE2 . GLN B 1 163 ? 12.395  1.221   -9.852  1.00 35.70  ? 163 GLN B NE2 1 
ATOM   4640  N N   . ARG B 1 164 ? 9.548   -4.415  -10.489 1.00 38.38  ? 164 ARG B N   1 
ATOM   4641  C CA  . ARG B 1 164 ? 8.175   -4.757  -10.144 1.00 42.78  ? 164 ARG B CA  1 
ATOM   4642  C C   . ARG B 1 164 ? 8.059   -5.197  -8.645  1.00 44.23  ? 164 ARG B C   1 
ATOM   4643  O O   . ARG B 1 164 ? 7.034   -4.978  -8.018  1.00 37.04  ? 164 ARG B O   1 
ATOM   4644  C CB  . ARG B 1 164 ? 7.665   -5.826  -11.098 1.00 43.89  ? 164 ARG B CB  1 
ATOM   4645  C CG  . ARG B 1 164 ? 6.282   -6.302  -10.713 1.00 52.36  ? 164 ARG B CG  1 
ATOM   4646  C CD  . ARG B 1 164 ? 5.521   -6.947  -11.829 1.00 54.77  ? 164 ARG B CD  1 
ATOM   4647  N NE  . ARG B 1 164 ? 5.644   -8.405  -11.797 1.00 63.75  ? 164 ARG B NE  1 
ATOM   4648  C CZ  . ARG B 1 164 ? 5.344   -9.178  -12.814 1.00 73.14  ? 164 ARG B CZ  1 
ATOM   4649  N NH1 . ARG B 1 164 ? 4.995   -8.625  -13.963 1.00 80.19  ? 164 ARG B NH1 1 
ATOM   4650  N NH2 . ARG B 1 164 ? 5.412   -10.500 -12.696 1.00 77.87  ? 164 ARG B NH2 1 
ATOM   4651  N N   . SER B 1 165 ? 9.105   -5.841  -8.093  1.00 40.22  ? 165 SER B N   1 
ATOM   4652  C CA  . SER B 1 165 ? 9.126   -6.178  -6.667  1.00 39.74  ? 165 SER B CA  1 
ATOM   4653  C C   . SER B 1 165 ? 9.727   -5.024  -5.837  1.00 37.24  ? 165 SER B C   1 
ATOM   4654  O O   . SER B 1 165 ? 9.194   -4.655  -4.788  1.00 33.11  ? 165 SER B O   1 
ATOM   4655  C CB  . SER B 1 165 ? 9.868   -7.464  -6.421  1.00 40.77  ? 165 SER B CB  1 
ATOM   4656  O OG  . SER B 1 165 ? 9.106   -8.577  -6.849  1.00 44.67  ? 165 SER B OG  1 
ATOM   4657  N N   . ILE B 1 166 ? 10.848  -4.496  -6.307  1.00 36.23  ? 166 ILE B N   1 
ATOM   4658  C CA  . ILE B 1 166 ? 11.685  -3.584  -5.533  1.00 38.11  ? 166 ILE B CA  1 
ATOM   4659  C C   . ILE B 1 166 ? 10.895  -2.309  -5.238  1.00 34.35  ? 166 ILE B C   1 
ATOM   4660  O O   . ILE B 1 166 ? 10.821  -1.885  -4.098  1.00 36.06  ? 166 ILE B O   1 
ATOM   4661  C CB  . ILE B 1 166 ? 13.026  -3.311  -6.301  1.00 41.91  ? 166 ILE B CB  1 
ATOM   4662  C CG1 . ILE B 1 166 ? 13.894  -4.460  -6.256  1.00 46.09  ? 166 ILE B CG1 1 
ATOM   4663  C CG2 . ILE B 1 166 ? 13.757  -2.085  -5.808  1.00 48.73  ? 166 ILE B CG2 1 
ATOM   4664  C CD1 . ILE B 1 166 ? 13.812  -5.231  -4.971  1.00 49.19  ? 166 ILE B CD1 1 
ATOM   4665  N N   . ALA B 1 167 ? 10.340  -1.678  -6.287  1.00 34.40  ? 167 ALA B N   1 
ATOM   4666  C CA  . ALA B 1 167 ? 9.780   -0.327  -6.161  1.00 32.89  ? 167 ALA B CA  1 
ATOM   4667  C C   . ALA B 1 167 ? 8.627   -0.305  -5.150  1.00 31.18  ? 167 ALA B C   1 
ATOM   4668  O O   . ALA B 1 167 ? 8.640   0.507   -4.241  1.00 31.66  ? 167 ALA B O   1 
ATOM   4669  C CB  . ALA B 1 167 ? 9.354   0.207   -7.516  1.00 32.45  ? 167 ALA B CB  1 
ATOM   4670  N N   . PRO B 1 168 ? 7.582   -1.165  -5.263  1.00 36.56  ? 168 PRO B N   1 
ATOM   4671  C CA  . PRO B 1 168 ? 6.491   -1.139  -4.280  1.00 40.87  ? 168 PRO B CA  1 
ATOM   4672  C C   . PRO B 1 168 ? 6.958   -1.473  -2.865  1.00 41.76  ? 168 PRO B C   1 
ATOM   4673  O O   . PRO B 1 168 ? 6.531   -0.823  -1.900  1.00 41.58  ? 168 PRO B O   1 
ATOM   4674  C CB  . PRO B 1 168 ? 5.428   -2.144  -4.799  1.00 37.54  ? 168 PRO B CB  1 
ATOM   4675  C CG  . PRO B 1 168 ? 6.183   -3.001  -5.805  1.00 39.99  ? 168 PRO B CG  1 
ATOM   4676  C CD  . PRO B 1 168 ? 7.330   -2.119  -6.363  1.00 38.28  ? 168 PRO B CD  1 
ATOM   4677  N N   . ALA B 1 169 ? 7.833   -2.475  -2.737  1.00 40.64  ? 169 ALA B N   1 
ATOM   4678  C CA  . ALA B 1 169 ? 8.291   -2.914  -1.415  1.00 41.00  ? 169 ALA B CA  1 
ATOM   4679  C C   . ALA B 1 169 ? 9.014   -1.767  -0.701  1.00 37.84  ? 169 ALA B C   1 
ATOM   4680  O O   . ALA B 1 169 ? 8.768   -1.511  0.467   1.00 35.64  ? 169 ALA B O   1 
ATOM   4681  C CB  . ALA B 1 169 ? 9.172   -4.131  -1.538  1.00 42.03  ? 169 ALA B CB  1 
ATOM   4682  N N   . LEU B 1 170 ? 9.879   -1.062  -1.423  1.00 39.52  ? 170 LEU B N   1 
ATOM   4683  C CA  . LEU B 1 170 ? 10.615  0.064   -0.848  1.00 39.06  ? 170 LEU B CA  1 
ATOM   4684  C C   . LEU B 1 170 ? 9.644   1.197   -0.495  1.00 38.92  ? 170 LEU B C   1 
ATOM   4685  O O   . LEU B 1 170 ? 9.729   1.788   0.589   1.00 40.91  ? 170 LEU B O   1 
ATOM   4686  C CB  . LEU B 1 170 ? 11.692  0.534   -1.813  1.00 38.42  ? 170 LEU B CB  1 
ATOM   4687  C CG  . LEU B 1 170 ? 12.965  -0.320  -1.860  1.00 44.56  ? 170 LEU B CG  1 
ATOM   4688  C CD1 . LEU B 1 170 ? 13.845  0.054   -3.057  1.00 46.73  ? 170 LEU B CD1 1 
ATOM   4689  C CD2 . LEU B 1 170 ? 13.747  -0.181  -0.564  1.00 40.08  ? 170 LEU B CD2 1 
ATOM   4690  N N   . ALA B 1 171 ? 8.719   1.493   -1.404  1.00 38.18  ? 171 ALA B N   1 
ATOM   4691  C CA  . ALA B 1 171 ? 7.768   2.576   -1.191  1.00 41.05  ? 171 ALA B CA  1 
ATOM   4692  C C   . ALA B 1 171 ? 6.957   2.330   0.091   1.00 38.90  ? 171 ALA B C   1 
ATOM   4693  O O   . ALA B 1 171 ? 6.704   3.262   0.847   1.00 36.88  ? 171 ALA B O   1 
ATOM   4694  C CB  . ALA B 1 171 ? 6.874   2.725   -2.399  1.00 41.23  ? 171 ALA B CB  1 
ATOM   4695  N N   . LEU B 1 172 ? 6.590   1.052   0.338   1.00 39.69  ? 172 LEU B N   1 
ATOM   4696  C CA  . LEU B 1 172 ? 5.758   0.667   1.490   1.00 35.74  ? 172 LEU B CA  1 
ATOM   4697  C C   . LEU B 1 172 ? 6.590   0.450   2.769   1.00 33.24  ? 172 LEU B C   1 
ATOM   4698  O O   . LEU B 1 172 ? 6.069   -0.058  3.746   1.00 40.50  ? 172 LEU B O   1 
ATOM   4699  C CB  . LEU B 1 172 ? 4.986   -0.603  1.125   1.00 38.45  ? 172 LEU B CB  1 
ATOM   4700  C CG  . LEU B 1 172 ? 3.869   -0.430  0.093   1.00 41.40  ? 172 LEU B CG  1 
ATOM   4701  C CD1 . LEU B 1 172 ? 3.281   -1.744  -0.352  1.00 40.76  ? 172 LEU B CD1 1 
ATOM   4702  C CD2 . LEU B 1 172 ? 2.791   0.458   0.655   1.00 44.39  ? 172 LEU B CD2 1 
ATOM   4703  N N   . GLY B 1 173 ? 7.886   0.805   2.750   1.00 35.01  ? 173 GLY B N   1 
ATOM   4704  C CA  . GLY B 1 173 ? 8.676   0.873   3.966   1.00 32.69  ? 173 GLY B CA  1 
ATOM   4705  C C   . GLY B 1 173 ? 9.492   -0.402  4.236   1.00 35.05  ? 173 GLY B C   1 
ATOM   4706  O O   . GLY B 1 173 ? 10.094  -0.537  5.313   1.00 34.34  ? 173 GLY B O   1 
ATOM   4707  N N   . ASN B 1 174 ? 9.558   -1.316  3.263   1.00 32.71  ? 174 ASN B N   1 
ATOM   4708  C CA  . ASN B 1 174 ? 10.420  -2.489  3.405   1.00 29.27  ? 174 ASN B CA  1 
ATOM   4709  C C   . ASN B 1 174 ? 11.870  -2.143  3.044   1.00 28.86  ? 174 ASN B C   1 
ATOM   4710  O O   . ASN B 1 174 ? 12.154  -1.122  2.395   1.00 28.97  ? 174 ASN B O   1 
ATOM   4711  C CB  . ASN B 1 174 ? 9.953   -3.648  2.549   1.00 32.04  ? 174 ASN B CB  1 
ATOM   4712  C CG  . ASN B 1 174 ? 8.625   -4.183  2.984   1.00 35.10  ? 174 ASN B CG  1 
ATOM   4713  O OD1 . ASN B 1 174 ? 8.535   -4.931  3.979   1.00 38.91  ? 174 ASN B OD1 1 
ATOM   4714  N ND2 . ASN B 1 174 ? 7.593   -3.854  2.240   1.00 36.85  ? 174 ASN B ND2 1 
ATOM   4715  N N   . ALA B 1 175 ? 12.786  -3.012  3.477   1.00 30.29  ? 175 ALA B N   1 
ATOM   4716  C CA  . ALA B 1 175 ? 14.140  -3.070  2.932   1.00 31.63  ? 175 ALA B CA  1 
ATOM   4717  C C   . ALA B 1 175 ? 14.245  -4.284  2.016   1.00 31.72  ? 175 ALA B C   1 
ATOM   4718  O O   . ALA B 1 175 ? 13.467  -5.216  2.167   1.00 32.88  ? 175 ALA B O   1 
ATOM   4719  C CB  . ALA B 1 175 ? 15.141  -3.142  4.041   1.00 31.83  ? 175 ALA B CB  1 
ATOM   4720  N N   . VAL B 1 176 ? 15.194  -4.238  1.044   1.00 33.39  ? 176 VAL B N   1 
ATOM   4721  C CA  . VAL B 1 176 ? 15.303  -5.265  -0.002  1.00 34.09  ? 176 VAL B CA  1 
ATOM   4722  C C   . VAL B 1 176 ? 16.767  -5.674  -0.160  1.00 33.62  ? 176 VAL B C   1 
ATOM   4723  O O   . VAL B 1 176 ? 17.666  -4.839  -0.089  1.00 30.68  ? 176 VAL B O   1 
ATOM   4724  C CB  . VAL B 1 176 ? 14.718  -4.823  -1.368  1.00 32.36  ? 176 VAL B CB  1 
ATOM   4725  C CG1 . VAL B 1 176 ? 13.232  -4.515  -1.273  1.00 35.01  ? 176 VAL B CG1 1 
ATOM   4726  C CG2 . VAL B 1 176 ? 15.450  -3.638  -1.944  1.00 32.57  ? 176 VAL B CG2 1 
ATOM   4727  N N   . VAL B 1 177 ? 16.968  -6.976  -0.398  1.00 31.76  ? 177 VAL B N   1 
ATOM   4728  C CA  . VAL B 1 177 ? 18.213  -7.520  -0.865  1.00 31.69  ? 177 VAL B CA  1 
ATOM   4729  C C   . VAL B 1 177 ? 17.931  -8.332  -2.123  1.00 31.20  ? 177 VAL B C   1 
ATOM   4730  O O   . VAL B 1 177 ? 17.053  -9.167  -2.132  1.00 31.03  ? 177 VAL B O   1 
ATOM   4731  C CB  . VAL B 1 177 ? 18.861  -8.393  0.230   1.00 37.44  ? 177 VAL B CB  1 
ATOM   4732  C CG1 . VAL B 1 177 ? 20.169  -9.024  -0.245  1.00 35.61  ? 177 VAL B CG1 1 
ATOM   4733  C CG2 . VAL B 1 177 ? 19.096  -7.605  1.518   1.00 40.67  ? 177 VAL B CG2 1 
ATOM   4734  N N   . VAL B 1 178 ? 18.705  -8.086  -3.173  1.00 33.22  ? 178 VAL B N   1 
ATOM   4735  C CA  . VAL B 1 178 ? 18.452  -8.679  -4.468  1.00 33.10  ? 178 VAL B CA  1 
ATOM   4736  C C   . VAL B 1 178 ? 19.606  -9.616  -4.836  1.00 36.70  ? 178 VAL B C   1 
ATOM   4737  O O   . VAL B 1 178 ? 20.769  -9.253  -4.705  1.00 39.19  ? 178 VAL B O   1 
ATOM   4738  C CB  . VAL B 1 178 ? 18.281  -7.589  -5.521  1.00 34.98  ? 178 VAL B CB  1 
ATOM   4739  C CG1 . VAL B 1 178 ? 18.189  -8.185  -6.923  1.00 35.99  ? 178 VAL B CG1 1 
ATOM   4740  C CG2 . VAL B 1 178 ? 17.078  -6.708  -5.231  1.00 36.97  ? 178 VAL B CG2 1 
ATOM   4741  N N   . LYS B 1 179 ? 19.264  -10.811 -5.317  1.00 36.87  ? 179 LYS B N   1 
ATOM   4742  C CA  . LYS B 1 179 ? 20.225  -11.713 -5.934  1.00 39.03  ? 179 LYS B CA  1 
ATOM   4743  C C   . LYS B 1 179 ? 19.925  -11.820 -7.434  1.00 38.71  ? 179 LYS B C   1 
ATOM   4744  O O   . LYS B 1 179 ? 18.979  -12.504 -7.848  1.00 35.14  ? 179 LYS B O   1 
ATOM   4745  C CB  . LYS B 1 179 ? 20.163  -13.094 -5.283  1.00 40.77  ? 179 LYS B CB  1 
ATOM   4746  C CG  . LYS B 1 179 ? 21.342  -13.999 -5.582  1.00 40.52  ? 179 LYS B CG  1 
ATOM   4747  C CD  . LYS B 1 179 ? 21.290  -15.304 -4.809  1.00 48.61  ? 179 LYS B CD  1 
ATOM   4748  C CE  . LYS B 1 179 ? 20.110  -16.166 -5.168  1.00 54.71  ? 179 LYS B CE  1 
ATOM   4749  N NZ  . LYS B 1 179 ? 20.176  -16.596 -6.574  1.00 59.58  ? 179 LYS B NZ  1 
ATOM   4750  N N   . PRO B 1 180 ? 20.694  -11.132 -8.298  1.00 39.09  ? 180 PRO B N   1 
ATOM   4751  C CA  . PRO B 1 180 ? 20.430  -11.155 -9.731  1.00 42.44  ? 180 PRO B CA  1 
ATOM   4752  C C   . PRO B 1 180 ? 20.937  -12.434 -10.367 1.00 38.64  ? 180 PRO B C   1 
ATOM   4753  O O   . PRO B 1 180 ? 21.706  -13.154 -9.762  1.00 39.94  ? 180 PRO B O   1 
ATOM   4754  C CB  . PRO B 1 180 ? 21.181  -9.925  -10.220 1.00 41.03  ? 180 PRO B CB  1 
ATOM   4755  C CG  . PRO B 1 180 ? 22.346  -9.827  -9.289  1.00 41.39  ? 180 PRO B CG  1 
ATOM   4756  C CD  . PRO B 1 180 ? 21.859  -10.326 -7.949  1.00 39.07  ? 180 PRO B CD  1 
ATOM   4757  N N   . ALA B 1 181 ? 20.479  -12.709 -11.593 1.00 47.44  ? 181 ALA B N   1 
ATOM   4758  C CA  . ALA B 1 181 ? 21.005  -13.836 -12.377 1.00 45.42  ? 181 ALA B CA  1 
ATOM   4759  C C   . ALA B 1 181 ? 22.466  -13.560 -12.762 1.00 42.06  ? 181 ALA B C   1 
ATOM   4760  O O   . ALA B 1 181 ? 22.866  -12.405 -12.984 1.00 41.75  ? 181 ALA B O   1 
ATOM   4761  C CB  . ALA B 1 181 ? 20.138  -14.070 -13.599 1.00 41.39  ? 181 ALA B CB  1 
ATOM   4762  N N   . SER B 1 182 ? 23.246  -14.614 -12.850 1.00 47.60  ? 182 SER B N   1 
ATOM   4763  C CA  . SER B 1 182 ? 24.689  -14.483 -13.075 1.00 60.92  ? 182 SER B CA  1 
ATOM   4764  C C   . SER B 1 182 ? 24.977  -13.835 -14.448 1.00 57.33  ? 182 SER B C   1 
ATOM   4765  O O   . SER B 1 182 ? 25.960  -13.128 -14.601 1.00 58.34  ? 182 SER B O   1 
ATOM   4766  C CB  . SER B 1 182 ? 25.388  -15.815 -12.940 1.00 62.97  ? 182 SER B CB  1 
ATOM   4767  O OG  . SER B 1 182 ? 25.362  -16.521 -14.164 1.00 78.25  ? 182 SER B OG  1 
ATOM   4768  N N   . ASP B 1 183 ? 24.091  -14.059 -15.424 1.00 49.28  ? 183 ASP B N   1 
ATOM   4769  C CA  . ASP B 1 183 ? 24.278  -13.527 -16.769 1.00 45.60  ? 183 ASP B CA  1 
ATOM   4770  C C   . ASP B 1 183 ? 23.978  -12.018 -16.833 1.00 43.92  ? 183 ASP B C   1 
ATOM   4771  O O   . ASP B 1 183 ? 24.471  -11.347 -17.730 1.00 42.00  ? 183 ASP B O   1 
ATOM   4772  C CB  . ASP B 1 183 ? 23.434  -14.284 -17.780 1.00 52.03  ? 183 ASP B CB  1 
ATOM   4773  C CG  . ASP B 1 183 ? 24.063  -15.556 -18.297 1.00 54.60  ? 183 ASP B CG  1 
ATOM   4774  O OD1 . ASP B 1 183 ? 25.111  -15.450 -18.968 1.00 60.15  ? 183 ASP B OD1 1 
ATOM   4775  O OD2 . ASP B 1 183 ? 23.545  -16.642 -17.965 1.00 58.35  ? 183 ASP B OD2 1 
ATOM   4776  N N   . THR B 1 184 ? 23.115  -11.503 -15.924 1.00 42.55  ? 184 THR B N   1 
ATOM   4777  C CA  . THR B 1 184 ? 22.659  -10.104 -16.003 1.00 47.83  ? 184 THR B CA  1 
ATOM   4778  C C   . THR B 1 184 ? 22.682  -9.450  -14.603 1.00 48.33  ? 184 THR B C   1 
ATOM   4779  O O   . THR B 1 184 ? 21.660  -8.976  -14.118 1.00 46.15  ? 184 THR B O   1 
ATOM   4780  C CB  . THR B 1 184 ? 21.247  -10.023 -16.633 1.00 50.86  ? 184 THR B CB  1 
ATOM   4781  O OG1 . THR B 1 184 ? 20.379  -10.908 -15.932 1.00 47.23  ? 184 THR B OG1 1 
ATOM   4782  C CG2 . THR B 1 184 ? 21.226  -10.406 -18.106 1.00 55.10  ? 184 THR B CG2 1 
ATOM   4783  N N   . PRO B 1 185 ? 23.850  -9.342  -13.942 1.00 47.64  ? 185 PRO B N   1 
ATOM   4784  C CA  . PRO B 1 185 ? 23.928  -8.658  -12.644 1.00 46.81  ? 185 PRO B CA  1 
ATOM   4785  C C   . PRO B 1 185 ? 23.672  -7.144  -12.679 1.00 40.49  ? 185 PRO B C   1 
ATOM   4786  O O   . PRO B 1 185 ? 23.091  -6.590  -11.758 1.00 43.30  ? 185 PRO B O   1 
ATOM   4787  C CB  . PRO B 1 185 ? 25.356  -8.996  -12.159 1.00 49.69  ? 185 PRO B CB  1 
ATOM   4788  C CG  . PRO B 1 185 ? 26.136  -9.259  -13.443 1.00 48.55  ? 185 PRO B CG  1 
ATOM   4789  C CD  . PRO B 1 185 ? 25.134  -9.929  -14.365 1.00 49.57  ? 185 PRO B CD  1 
ATOM   4790  N N   . VAL B 1 186 ? 24.120  -6.463  -13.733 1.00 37.59  ? 186 VAL B N   1 
ATOM   4791  C CA  . VAL B 1 186 ? 23.956  -4.977  -13.791 1.00 37.98  ? 186 VAL B CA  1 
ATOM   4792  C C   . VAL B 1 186 ? 22.458  -4.667  -13.943 1.00 38.00  ? 186 VAL B C   1 
ATOM   4793  O O   . VAL B 1 186 ? 21.931  -3.882  -13.130 1.00 45.56  ? 186 VAL B O   1 
ATOM   4794  C CB  . VAL B 1 186 ? 24.787  -4.327  -14.914 1.00 34.80  ? 186 VAL B CB  1 
ATOM   4795  C CG1 . VAL B 1 186 ? 24.463  -2.849  -15.088 1.00 34.21  ? 186 VAL B CG1 1 
ATOM   4796  C CG2 . VAL B 1 186 ? 26.280  -4.528  -14.695 1.00 35.36  ? 186 VAL B CG2 1 
ATOM   4797  N N   . CYS B 1 187 ? 21.803  -5.288  -14.922 1.00 37.44  ? 187 CYS B N   1 
ATOM   4798  C CA  . CYS B 1 187 ? 20.347  -5.084  -15.154 1.00 41.40  ? 187 CYS B CA  1 
ATOM   4799  C C   . CYS B 1 187 ? 19.560  -5.579  -13.926 1.00 43.43  ? 187 CYS B C   1 
ATOM   4800  O O   . CYS B 1 187 ? 18.549  -4.931  -13.594 1.00 39.57  ? 187 CYS B O   1 
ATOM   4801  C CB  . CYS B 1 187 ? 19.902  -5.719  -16.467 1.00 47.25  ? 187 CYS B CB  1 
ATOM   4802  S SG  . CYS B 1 187 ? 20.591  -4.882  -17.918 1.00 50.36  ? 187 CYS B SG  1 
ATOM   4803  N N   . GLY B 1 188 ? 19.975  -6.686  -13.300 1.00 44.18  ? 188 GLY B N   1 
ATOM   4804  C CA  . GLY B 1 188 ? 19.176  -7.160  -12.159 1.00 41.69  ? 188 GLY B CA  1 
ATOM   4805  C C   . GLY B 1 188 ? 19.546  -6.422  -10.889 1.00 41.73  ? 188 GLY B C   1 
ATOM   4806  O O   . GLY B 1 188 ? 19.998  -7.076  -9.938  1.00 46.42  ? 188 GLY B O   1 
ATOM   4807  N N   . GLY B 1 189 ? 19.314  -5.112  -10.847 1.00 36.41  ? 189 GLY B N   1 
ATOM   4808  C CA  . GLY B 1 189 ? 19.467  -4.293  -9.627  1.00 35.83  ? 189 GLY B CA  1 
ATOM   4809  C C   . GLY B 1 189 ? 20.792  -3.612  -9.345  1.00 34.60  ? 189 GLY B C   1 
ATOM   4810  O O   . GLY B 1 189 ? 20.771  -2.713  -8.488  1.00 40.83  ? 189 GLY B O   1 
ATOM   4811  N N   . LEU B 1 190 ? 21.895  -3.936  -10.022 1.00 33.55  ? 190 LEU B N   1 
ATOM   4812  C CA  . LEU B 1 190 ? 23.110  -3.116  -9.760  1.00 33.27  ? 190 LEU B CA  1 
ATOM   4813  C C   . LEU B 1 190 ? 22.851  -1.685  -10.256 1.00 32.68  ? 190 LEU B C   1 
ATOM   4814  O O   . LEU B 1 190 ? 23.141  -0.731  -9.505  1.00 37.86  ? 190 LEU B O   1 
ATOM   4815  C CB  . LEU B 1 190 ? 24.351  -3.720  -10.411 1.00 35.23  ? 190 LEU B CB  1 
ATOM   4816  C CG  . LEU B 1 190 ? 25.063  -4.825  -9.625  1.00 35.68  ? 190 LEU B CG  1 
ATOM   4817  C CD1 . LEU B 1 190 ? 26.172  -5.434  -10.464 1.00 38.03  ? 190 LEU B CD1 1 
ATOM   4818  C CD2 . LEU B 1 190 ? 25.621  -4.285  -8.326  1.00 33.23  ? 190 LEU B CD2 1 
ATOM   4819  N N   . LEU B 1 191 ? 22.279  -1.553  -11.459 1.00 34.99  ? 191 LEU B N   1 
ATOM   4820  C CA  . LEU B 1 191 ? 21.908  -0.226  -12.021 1.00 38.40  ? 191 LEU B CA  1 
ATOM   4821  C C   . LEU B 1 191 ? 20.796  0.406   -11.177 1.00 37.96  ? 191 LEU B C   1 
ATOM   4822  O O   . LEU B 1 191 ? 20.860  1.621   -10.920 1.00 33.29  ? 191 LEU B O   1 
ATOM   4823  C CB  . LEU B 1 191 ? 21.490  -0.384  -13.482 1.00 37.47  ? 191 LEU B CB  1 
ATOM   4824  C CG  . LEU B 1 191 ? 21.743  0.825   -14.387 1.00 39.54  ? 191 LEU B CG  1 
ATOM   4825  C CD1 . LEU B 1 191 ? 23.223  1.160   -14.426 1.00 41.87  ? 191 LEU B CD1 1 
ATOM   4826  C CD2 . LEU B 1 191 ? 21.217  0.563   -15.786 1.00 41.47  ? 191 LEU B CD2 1 
ATOM   4827  N N   . LEU B 1 192 ? 19.825  -0.409  -10.762 1.00 36.44  ? 192 LEU B N   1 
ATOM   4828  C CA  . LEU B 1 192 ? 18.662  0.103   -9.994  1.00 35.89  ? 192 LEU B CA  1 
ATOM   4829  C C   . LEU B 1 192 ? 19.143  0.682   -8.658  1.00 37.80  ? 192 LEU B C   1 
ATOM   4830  O O   . LEU B 1 192 ? 18.606  1.722   -8.242  1.00 38.54  ? 192 LEU B O   1 
ATOM   4831  C CB  . LEU B 1 192 ? 17.650  -1.027  -9.826  1.00 36.27  ? 192 LEU B CB  1 
ATOM   4832  C CG  . LEU B 1 192 ? 16.894  -1.418  -11.100 1.00 34.06  ? 192 LEU B CG  1 
ATOM   4833  C CD1 . LEU B 1 192 ? 16.042  -2.659  -10.912 1.00 31.01  ? 192 LEU B CD1 1 
ATOM   4834  C CD2 . LEU B 1 192 ? 16.053  -0.257  -11.596 1.00 33.12  ? 192 LEU B CD2 1 
ATOM   4835  N N   . ALA B 1 193 ? 20.109  0.022   -8.018  1.00 40.87  ? 193 ALA B N   1 
ATOM   4836  C CA  . ALA B 1 193 ? 20.658  0.529   -6.741  1.00 34.96  ? 193 ALA B CA  1 
ATOM   4837  C C   . ALA B 1 193 ? 21.319  1.886   -6.977  1.00 35.41  ? 193 ALA B C   1 
ATOM   4838  O O   . ALA B 1 193 ? 21.145  2.786   -6.137  1.00 35.16  ? 193 ALA B O   1 
ATOM   4839  C CB  . ALA B 1 193 ? 21.623  -0.476  -6.165  1.00 36.14  ? 193 ALA B CB  1 
ATOM   4840  N N   . ARG B 1 194 ? 22.040  2.031   -8.089  1.00 37.89  ? 194 ARG B N   1 
ATOM   4841  C CA  . ARG B 1 194 ? 22.658  3.340   -8.426  1.00 44.89  ? 194 ARG B CA  1 
ATOM   4842  C C   . ARG B 1 194 ? 21.555  4.388   -8.646  1.00 39.99  ? 194 ARG B C   1 
ATOM   4843  O O   . ARG B 1 194 ? 21.727  5.530   -8.185  1.00 37.72  ? 194 ARG B O   1 
ATOM   4844  C CB  . ARG B 1 194 ? 23.543  3.222   -9.669  1.00 50.00  ? 194 ARG B CB  1 
ATOM   4845  C CG  . ARG B 1 194 ? 24.791  2.380   -9.464  1.00 50.00  ? 194 ARG B CG  1 
ATOM   4846  C CD  . ARG B 1 194 ? 25.976  3.150   -8.904  1.00 50.00  ? 194 ARG B CD  1 
ATOM   4847  N NE  . ARG B 1 194 ? 26.255  4.360   -9.672  1.00 50.00  ? 194 ARG B NE  1 
ATOM   4848  C CZ  . ARG B 1 194 ? 27.158  5.267   -9.331  1.00 50.00  ? 194 ARG B CZ  1 
ATOM   4849  N NH1 . ARG B 1 194 ? 27.881  5.105   -8.230  1.00 50.00  ? 194 ARG B NH1 1 
ATOM   4850  N NH2 . ARG B 1 194 ? 27.346  6.339   -10.090 1.00 50.00  ? 194 ARG B NH2 1 
ATOM   4851  N N   . ILE B 1 195 ? 20.467  4.003   -9.315  1.00 37.23  ? 195 ILE B N   1 
ATOM   4852  C CA  . ILE B 1 195 ? 19.341  4.946   -9.585  1.00 39.59  ? 195 ILE B CA  1 
ATOM   4853  C C   . ILE B 1 195 ? 18.696  5.340   -8.249  1.00 37.45  ? 195 ILE B C   1 
ATOM   4854  O O   . ILE B 1 195 ? 18.486  6.549   -8.028  1.00 32.61  ? 195 ILE B O   1 
ATOM   4855  C CB  . ILE B 1 195 ? 18.321  4.307   -10.544 1.00 40.54  ? 195 ILE B CB  1 
ATOM   4856  C CG1 . ILE B 1 195 ? 18.899  4.133   -11.946 1.00 46.01  ? 195 ILE B CG1 1 
ATOM   4857  C CG2 . ILE B 1 195 ? 17.008  5.092   -10.569 1.00 43.23  ? 195 ILE B CG2 1 
ATOM   4858  C CD1 . ILE B 1 195 ? 18.182  3.090   -12.784 1.00 45.25  ? 195 ILE B CD1 1 
ATOM   4859  N N   . PHE B 1 196 ? 18.418  4.359   -7.390  1.00 35.49  ? 196 PHE B N   1 
ATOM   4860  C CA  . PHE B 1 196 ? 17.746  4.652   -6.135  1.00 37.72  ? 196 PHE B CA  1 
ATOM   4861  C C   . PHE B 1 196 ? 18.658  5.482   -5.233  1.00 41.91  ? 196 PHE B C   1 
ATOM   4862  O O   . PHE B 1 196 ? 18.186  6.331   -4.471  1.00 36.57  ? 196 PHE B O   1 
ATOM   4863  C CB  . PHE B 1 196 ? 17.319  3.363   -5.433  1.00 39.10  ? 196 PHE B CB  1 
ATOM   4864  C CG  . PHE B 1 196 ? 15.916  2.928   -5.790  1.00 37.45  ? 196 PHE B CG  1 
ATOM   4865  C CD1 . PHE B 1 196 ? 14.818  3.629   -5.312  1.00 39.95  ? 196 PHE B CD1 1 
ATOM   4866  C CD2 . PHE B 1 196 ? 15.695  1.841   -6.599  1.00 36.31  ? 196 PHE B CD2 1 
ATOM   4867  C CE1 . PHE B 1 196 ? 13.540  3.252   -5.650  1.00 37.09  ? 196 PHE B CE1 1 
ATOM   4868  C CE2 . PHE B 1 196 ? 14.405  1.448   -6.912  1.00 39.26  ? 196 PHE B CE2 1 
ATOM   4869  C CZ  . PHE B 1 196 ? 13.335  2.165   -6.445  1.00 37.01  ? 196 PHE B CZ  1 
ATOM   4870  N N   . GLU B 1 197 ? 19.965  5.231   -5.306  1.00 45.07  ? 197 GLU B N   1 
ATOM   4871  C CA  . GLU B 1 197 ? 20.907  5.991   -4.504  1.00 43.61  ? 197 GLU B CA  1 
ATOM   4872  C C   . GLU B 1 197 ? 20.915  7.446   -4.969  1.00 42.36  ? 197 GLU B C   1 
ATOM   4873  O O   . GLU B 1 197 ? 20.895  8.364   -4.149  1.00 45.26  ? 197 GLU B O   1 
ATOM   4874  C CB  . GLU B 1 197 ? 22.297  5.399   -4.573  1.00 46.09  ? 197 GLU B CB  1 
ATOM   4875  C CG  . GLU B 1 197 ? 23.265  6.053   -3.595  1.00 49.12  ? 197 GLU B CG  1 
ATOM   4876  C CD  . GLU B 1 197 ? 24.637  6.179   -4.153  1.00 56.21  ? 197 GLU B CD  1 
ATOM   4877  O OE1 . GLU B 1 197 ? 24.746  6.874   -5.188  1.00 61.90  ? 197 GLU B OE1 1 
ATOM   4878  O OE2 . GLU B 1 197 ? 25.589  5.568   -3.600  1.00 62.99  ? 197 GLU B OE2 1 
ATOM   4879  N N   . GLU B 1 198 ? 20.933  7.652   -6.285  1.00 39.89  ? 198 GLU B N   1 
ATOM   4880  C CA  . GLU B 1 198 ? 20.893  8.993   -6.840  1.00 41.19  ? 198 GLU B CA  1 
ATOM   4881  C C   . GLU B 1 198 ? 19.607  9.708   -6.389  1.00 42.43  ? 198 GLU B C   1 
ATOM   4882  O O   . GLU B 1 198 ? 19.616  10.910  -6.181  1.00 44.38  ? 198 GLU B O   1 
ATOM   4883  C CB  . GLU B 1 198 ? 21.004  8.939   -8.360  1.00 44.07  ? 198 GLU B CB  1 
ATOM   4884  C CG  . GLU B 1 198 ? 21.109  10.319  -9.005  1.00 46.32  ? 198 GLU B CG  1 
ATOM   4885  C CD  . GLU B 1 198 ? 21.375  10.294  -10.496 1.00 47.26  ? 198 GLU B CD  1 
ATOM   4886  O OE1 . GLU B 1 198 ? 21.517  9.186   -11.066 1.00 47.25  ? 198 GLU B OE1 1 
ATOM   4887  O OE2 . GLU B 1 198 ? 21.432  11.375  -11.086 1.00 58.45  ? 198 GLU B OE2 1 
ATOM   4888  N N   . ALA B 1 199 ? 18.516  8.940   -6.218  1.00 40.95  ? 199 ALA B N   1 
ATOM   4889  C CA  . ALA B 1 199 ? 17.214  9.502   -5.878  1.00 41.72  ? 199 ALA B CA  1 
ATOM   4890  C C   . ALA B 1 199 ? 17.063  9.738   -4.363  1.00 37.58  ? 199 ALA B C   1 
ATOM   4891  O O   . ALA B 1 199 ? 16.022  10.186  -3.927  1.00 39.43  ? 199 ALA B O   1 
ATOM   4892  C CB  . ALA B 1 199 ? 16.118  8.584   -6.393  1.00 45.05  ? 199 ALA B CB  1 
ATOM   4893  N N   . GLY B 1 200 ? 18.069  9.362   -3.568  1.00 38.18  ? 200 GLY B N   1 
ATOM   4894  C CA  . GLY B 1 200 ? 18.120  9.744   -2.152  1.00 33.16  ? 200 GLY B CA  1 
ATOM   4895  C C   . GLY B 1 200 ? 17.668  8.609   -1.200  1.00 32.63  ? 200 GLY B C   1 
ATOM   4896  O O   . GLY B 1 200 ? 17.409  8.851   -0.029  1.00 31.95  ? 200 GLY B O   1 
ATOM   4897  N N   . LEU B 1 201 ? 17.617  7.369   -1.673  1.00 31.29  ? 201 LEU B N   1 
ATOM   4898  C CA  . LEU B 1 201 ? 17.290  6.258   -0.772  1.00 33.52  ? 201 LEU B CA  1 
ATOM   4899  C C   . LEU B 1 201 ? 18.397  6.110   0.279   1.00 35.40  ? 201 LEU B C   1 
ATOM   4900  O O   . LEU B 1 201 ? 19.555  5.998   -0.054  1.00 42.52  ? 201 LEU B O   1 
ATOM   4901  C CB  . LEU B 1 201 ? 17.094  4.973   -1.572  1.00 35.57  ? 201 LEU B CB  1 
ATOM   4902  C CG  . LEU B 1 201 ? 16.595  3.745   -0.796  1.00 39.08  ? 201 LEU B CG  1 
ATOM   4903  C CD1 . LEU B 1 201 ? 15.088  3.785   -0.620  1.00 42.64  ? 201 LEU B CD1 1 
ATOM   4904  C CD2 . LEU B 1 201 ? 17.006  2.444   -1.498  1.00 36.82  ? 201 LEU B CD2 1 
ATOM   4905  N N   . PRO B 1 202 ? 18.084  6.086   1.584   1.00 38.83  ? 202 PRO B N   1 
ATOM   4906  C CA  . PRO B 1 202 ? 19.129  5.939   2.602   1.00 38.39  ? 202 PRO B CA  1 
ATOM   4907  C C   . PRO B 1 202 ? 19.956  4.671   2.403   1.00 40.83  ? 202 PRO B C   1 
ATOM   4908  O O   . PRO B 1 202 ? 19.467  3.664   1.892   1.00 45.48  ? 202 PRO B O   1 
ATOM   4909  C CB  . PRO B 1 202 ? 18.358  5.924   3.946   1.00 39.59  ? 202 PRO B CB  1 
ATOM   4910  C CG  . PRO B 1 202 ? 17.011  6.583   3.622   1.00 38.64  ? 202 PRO B CG  1 
ATOM   4911  C CD  . PRO B 1 202 ? 16.741  6.268   2.154   1.00 41.81  ? 202 PRO B CD  1 
ATOM   4912  N N   . ALA B 1 203 ? 21.193  4.721   2.857   1.00 41.13  ? 203 ALA B N   1 
ATOM   4913  C CA  . ALA B 1 203 ? 22.141  3.665   2.610   1.00 39.83  ? 203 ALA B CA  1 
ATOM   4914  C C   . ALA B 1 203 ? 21.789  2.446   3.449   1.00 39.58  ? 203 ALA B C   1 
ATOM   4915  O O   . ALA B 1 203 ? 21.497  2.570   4.640   1.00 41.10  ? 203 ALA B O   1 
ATOM   4916  C CB  . ALA B 1 203 ? 23.531  4.163   2.919   1.00 42.42  ? 203 ALA B CB  1 
ATOM   4917  N N   . GLY B 1 204 ? 21.865  1.261   2.834   1.00 35.51  ? 204 GLY B N   1 
ATOM   4918  C CA  . GLY B 1 204 ? 21.625  0.010   3.551   1.00 32.39  ? 204 GLY B CA  1 
ATOM   4919  C C   . GLY B 1 204 ? 20.227  -0.582  3.276   1.00 33.15  ? 204 GLY B C   1 
ATOM   4920  O O   . GLY B 1 204 ? 19.990  -1.745  3.587   1.00 33.38  ? 204 GLY B O   1 
ATOM   4921  N N   . LEU B 1 205 ? 19.308  0.217   2.673   1.00 32.16  ? 205 LEU B N   1 
ATOM   4922  C CA  . LEU B 1 205 ? 17.956  -0.271  2.384   1.00 34.98  ? 205 LEU B CA  1 
ATOM   4923  C C   . LEU B 1 205 ? 17.967  -1.188  1.168   1.00 40.19  ? 205 LEU B C   1 
ATOM   4924  O O   . LEU B 1 205 ? 17.062  -2.003  1.013   1.00 34.39  ? 205 LEU B O   1 
ATOM   4925  C CB  . LEU B 1 205 ? 16.984  0.884   2.203   1.00 33.94  ? 205 LEU B CB  1 
ATOM   4926  C CG  . LEU B 1 205 ? 16.698  1.665   3.498   1.00 40.21  ? 205 LEU B CG  1 
ATOM   4927  C CD1 . LEU B 1 205 ? 16.019  2.983   3.264   1.00 37.74  ? 205 LEU B CD1 1 
ATOM   4928  C CD2 . LEU B 1 205 ? 15.878  0.785   4.462   1.00 38.88  ? 205 LEU B CD2 1 
ATOM   4929  N N   . PHE B 1 206 ? 18.991  -1.037  0.300   1.00 39.64  ? 206 PHE B N   1 
ATOM   4930  C CA  . PHE B 1 206 ? 19.050  -1.770  -0.957  1.00 36.79  ? 206 PHE B CA  1 
ATOM   4931  C C   . PHE B 1 206 ? 20.450  -2.349  -1.115  1.00 35.71  ? 206 PHE B C   1 
ATOM   4932  O O   . PHE B 1 206 ? 21.387  -1.619  -1.423  1.00 33.27  ? 206 PHE B O   1 
ATOM   4933  C CB  . PHE B 1 206 ? 18.705  -0.847  -2.136  1.00 36.95  ? 206 PHE B CB  1 
ATOM   4934  C CG  . PHE B 1 206 ? 18.516  -1.520  -3.503  1.00 34.48  ? 206 PHE B CG  1 
ATOM   4935  C CD1 . PHE B 1 206 ? 18.816  -2.860  -3.701  1.00 33.04  ? 206 PHE B CD1 1 
ATOM   4936  C CD2 . PHE B 1 206 ? 18.064  -0.785  -4.600  1.00 34.64  ? 206 PHE B CD2 1 
ATOM   4937  C CE1 . PHE B 1 206 ? 18.641  -3.454  -4.939  1.00 32.77  ? 206 PHE B CE1 1 
ATOM   4938  C CE2 . PHE B 1 206 ? 17.881  -1.391  -5.829  1.00 33.52  ? 206 PHE B CE2 1 
ATOM   4939  C CZ  . PHE B 1 206 ? 18.202  -2.715  -6.001  1.00 34.98  ? 206 PHE B CZ  1 
ATOM   4940  N N   . SER B 1 207 ? 20.563  -3.678  -0.939  1.00 30.92  ? 207 SER B N   1 
ATOM   4941  C CA  . SER B 1 207 ? 21.799  -4.389  -1.194  1.00 34.31  ? 207 SER B CA  1 
ATOM   4942  C C   . SER B 1 207 ? 21.619  -5.362  -2.356  1.00 36.06  ? 207 SER B C   1 
ATOM   4943  O O   . SER B 1 207 ? 20.529  -5.879  -2.568  1.00 40.82  ? 207 SER B O   1 
ATOM   4944  C CB  . SER B 1 207 ? 22.294  -5.104  0.058   1.00 37.61  ? 207 SER B CB  1 
ATOM   4945  O OG  . SER B 1 207 ? 22.980  -4.199  0.936   1.00 34.60  ? 207 SER B OG  1 
ATOM   4946  N N   . VAL B 1 208 ? 22.724  -5.581  -3.113  1.00 38.98  ? 208 VAL B N   1 
ATOM   4947  C CA  . VAL B 1 208 ? 22.767  -6.527  -4.233  1.00 35.60  ? 208 VAL B CA  1 
ATOM   4948  C C   . VAL B 1 208 ? 23.904  -7.521  -3.987  1.00 36.65  ? 208 VAL B C   1 
ATOM   4949  O O   . VAL B 1 208 ? 25.020  -7.130  -3.689  1.00 38.43  ? 208 VAL B O   1 
ATOM   4950  C CB  . VAL B 1 208 ? 22.962  -5.813  -5.579  1.00 31.18  ? 208 VAL B CB  1 
ATOM   4951  C CG1 . VAL B 1 208 ? 23.025  -6.802  -6.727  1.00 33.26  ? 208 VAL B CG1 1 
ATOM   4952  C CG2 . VAL B 1 208 ? 21.886  -4.781  -5.837  1.00 31.57  ? 208 VAL B CG2 1 
ATOM   4953  N N   . VAL B 1 209 ? 23.612  -8.797  -4.135  1.00 34.73  ? 209 VAL B N   1 
ATOM   4954  C CA  . VAL B 1 209 ? 24.556  -9.830  -3.799  1.00 36.73  ? 209 VAL B CA  1 
ATOM   4955  C C   . VAL B 1 209 ? 24.822  -10.648 -5.047  1.00 38.83  ? 209 VAL B C   1 
ATOM   4956  O O   . VAL B 1 209 ? 23.971  -11.403 -5.470  1.00 39.89  ? 209 VAL B O   1 
ATOM   4957  C CB  . VAL B 1 209 ? 24.037  -10.709 -2.645  1.00 42.38  ? 209 VAL B CB  1 
ATOM   4958  C CG1 . VAL B 1 209 ? 24.682  -12.078 -2.639  1.00 45.78  ? 209 VAL B CG1 1 
ATOM   4959  C CG2 . VAL B 1 209 ? 24.221  -10.031 -1.299  1.00 45.46  ? 209 VAL B CG2 1 
ATOM   4960  N N   . VAL B 1 210 ? 26.033  -10.470 -5.625  1.00 42.60  ? 210 VAL B N   1 
ATOM   4961  C CA  . VAL B 1 210 ? 26.467  -11.178 -6.831  1.00 40.45  ? 210 VAL B CA  1 
ATOM   4962  C C   . VAL B 1 210 ? 27.517  -12.207 -6.443  1.00 45.12  ? 210 VAL B C   1 
ATOM   4963  O O   . VAL B 1 210 ? 28.617  -11.839 -6.016  1.00 47.70  ? 210 VAL B O   1 
ATOM   4964  C CB  . VAL B 1 210 ? 27.036  -10.168 -7.834  1.00 39.21  ? 210 VAL B CB  1 
ATOM   4965  C CG1 . VAL B 1 210 ? 27.405  -10.819 -9.154  1.00 37.49  ? 210 VAL B CG1 1 
ATOM   4966  C CG2 . VAL B 1 210 ? 26.083  -9.010  -8.056  1.00 41.60  ? 210 VAL B CG2 1 
ATOM   4967  N N   . GLY B 1 211 ? 27.166  -13.487 -6.531  1.00 46.44  ? 211 GLY B N   1 
ATOM   4968  C CA  . GLY B 1 211 ? 27.979  -14.516 -5.895  1.00 59.08  ? 211 GLY B CA  1 
ATOM   4969  C C   . GLY B 1 211 ? 27.832  -15.898 -6.553  1.00 64.47  ? 211 GLY B C   1 
ATOM   4970  O O   . GLY B 1 211 ? 26.952  -16.121 -7.404  1.00 58.20  ? 211 GLY B O   1 
ATOM   4971  N N   . PRO B 1 212 ? 28.687  -16.873 -6.155  1.00 79.32  ? 212 PRO B N   1 
ATOM   4972  C CA  . PRO B 1 212 ? 28.609  -18.230 -6.689  1.00 88.04  ? 212 PRO B CA  1 
ATOM   4973  C C   . PRO B 1 212 ? 27.330  -18.922 -6.210  1.00 89.02  ? 212 PRO B C   1 
ATOM   4974  O O   . PRO B 1 212 ? 27.061  -18.974 -4.998  1.00 83.31  ? 212 PRO B O   1 
ATOM   4975  C CB  . PRO B 1 212 ? 29.912  -18.940 -6.163  1.00 89.25  ? 212 PRO B CB  1 
ATOM   4976  C CG  . PRO B 1 212 ? 30.753  -17.802 -5.522  1.00 89.21  ? 212 PRO B CG  1 
ATOM   4977  C CD  . PRO B 1 212 ? 29.761  -16.710 -5.156  1.00 82.86  ? 212 PRO B CD  1 
ATOM   4978  N N   . GLY B 1 213 ? 26.552  -19.455 -7.178  1.00 77.67  ? 213 GLY B N   1 
ATOM   4979  C CA  . GLY B 1 213 ? 25.290  -20.131 -6.892  1.00 71.38  ? 213 GLY B CA  1 
ATOM   4980  C C   . GLY B 1 213 ? 25.460  -21.252 -5.862  1.00 76.54  ? 213 GLY B C   1 
ATOM   4981  O O   . GLY B 1 213 ? 24.518  -21.595 -5.160  1.00 71.13  ? 213 GLY B O   1 
ATOM   4982  N N   . SER B 1 214 ? 26.674  -21.822 -5.796  1.00 87.43  ? 214 SER B N   1 
ATOM   4983  C CA  . SER B 1 214 ? 27.018  -22.805 -4.776  1.00 82.33  ? 214 SER B CA  1 
ATOM   4984  C C   . SER B 1 214 ? 26.996  -22.157 -3.391  1.00 87.01  ? 214 SER B C   1 
ATOM   4985  O O   . SER B 1 214 ? 26.324  -22.640 -2.493  1.00 101.80 ? 214 SER B O   1 
ATOM   4986  C CB  . SER B 1 214 ? 28.377  -23.467 -5.064  1.00 80.39  ? 214 SER B CB  1 
ATOM   4987  O OG  . SER B 1 214 ? 29.417  -22.509 -5.242  1.00 70.91  ? 214 SER B OG  1 
ATOM   4988  N N   . GLU B 1 215 ? 27.717  -21.040 -3.242  1.00 93.21  ? 215 GLU B N   1 
ATOM   4989  C CA  . GLU B 1 215 ? 27.935  -20.433 -1.933  1.00 92.97  ? 215 GLU B CA  1 
ATOM   4990  C C   . GLU B 1 215 ? 26.644  -19.762 -1.441  1.00 87.05  ? 215 GLU B C   1 
ATOM   4991  O O   . GLU B 1 215 ? 26.094  -20.165 -0.418  1.00 90.83  ? 215 GLU B O   1 
ATOM   4992  C CB  . GLU B 1 215 ? 29.118  -19.456 -1.959  1.00 91.82  ? 215 GLU B CB  1 
ATOM   4993  C CG  . GLU B 1 215 ? 29.399  -18.818 -0.593  1.00 94.47  ? 215 GLU B CG  1 
ATOM   4994  C CD  . GLU B 1 215 ? 30.867  -18.734 -0.187  1.00 81.94  ? 215 GLU B CD  1 
ATOM   4995  O OE1 . GLU B 1 215 ? 31.124  -18.625 1.025   1.00 69.13  ? 215 GLU B OE1 1 
ATOM   4996  O OE2 . GLU B 1 215 ? 31.745  -18.775 -1.069  1.00 83.14  ? 215 GLU B OE2 1 
ATOM   4997  N N   . ILE B 1 216 ? 26.179  -18.730 -2.169  1.00 75.02  ? 216 ILE B N   1 
ATOM   4998  C CA  . ILE B 1 216 ? 25.156  -17.827 -1.647  1.00 68.97  ? 216 ILE B CA  1 
ATOM   4999  C C   . ILE B 1 216 ? 23.756  -18.349 -1.974  1.00 56.57  ? 216 ILE B C   1 
ATOM   5000  O O   . ILE B 1 216 ? 22.790  -17.830 -1.465  1.00 61.12  ? 216 ILE B O   1 
ATOM   5001  C CB  . ILE B 1 216 ? 25.333  -16.395 -2.183  1.00 75.67  ? 216 ILE B CB  1 
ATOM   5002  C CG1 . ILE B 1 216 ? 25.559  -16.382 -3.669  1.00 85.94  ? 216 ILE B CG1 1 
ATOM   5003  C CG2 . ILE B 1 216 ? 26.437  -15.657 -1.436  1.00 77.25  ? 216 ILE B CG2 1 
ATOM   5004  C CD1 . ILE B 1 216 ? 24.941  -15.189 -4.374  1.00 97.06  ? 216 ILE B CD1 1 
ATOM   5005  N N   . GLY B 1 217 ? 23.650  -19.334 -2.862  1.00 52.90  ? 217 GLY B N   1 
ATOM   5006  C CA  . GLY B 1 217 ? 22.363  -19.664 -3.485  1.00 48.64  ? 217 GLY B CA  1 
ATOM   5007  C C   . GLY B 1 217 ? 21.299  -20.055 -2.452  1.00 51.39  ? 217 GLY B C   1 
ATOM   5008  O O   . GLY B 1 217 ? 20.276  -19.388 -2.334  1.00 49.71  ? 217 GLY B O   1 
ATOM   5009  N N   . ASP B 1 218 ? 21.555  -21.159 -1.726  1.00 50.86  ? 218 ASP B N   1 
ATOM   5010  C CA  . ASP B 1 218 ? 20.618  -21.695 -0.765  1.00 49.65  ? 218 ASP B CA  1 
ATOM   5011  C C   . ASP B 1 218 ? 20.568  -20.803 0.471   1.00 48.18  ? 218 ASP B C   1 
ATOM   5012  O O   . ASP B 1 218 ? 19.521  -20.662 1.083   1.00 50.38  ? 218 ASP B O   1 
ATOM   5013  C CB  . ASP B 1 218 ? 20.957  -23.131 -0.412  1.00 54.21  ? 218 ASP B CB  1 
ATOM   5014  C CG  . ASP B 1 218 ? 20.808  -24.123 -1.551  1.00 60.49  ? 218 ASP B CG  1 
ATOM   5015  O OD1 . ASP B 1 218 ? 20.430  -23.688 -2.663  1.00 58.46  ? 218 ASP B OD1 1 
ATOM   5016  O OD2 . ASP B 1 218 ? 21.088  -25.315 -1.323  1.00 69.12  ? 218 ASP B OD2 1 
ATOM   5017  N N   . ALA B 1 219 ? 21.696  -20.196 0.826   1.00 42.96  ? 219 ALA B N   1 
ATOM   5018  C CA  . ALA B 1 219 ? 21.767  -19.378 2.035   1.00 43.55  ? 219 ALA B CA  1 
ATOM   5019  C C   . ALA B 1 219 ? 20.859  -18.149 1.896   1.00 40.72  ? 219 ALA B C   1 
ATOM   5020  O O   . ALA B 1 219 ? 20.299  -17.685 2.869   1.00 44.48  ? 219 ALA B O   1 
ATOM   5021  C CB  . ALA B 1 219 ? 23.225  -18.970 2.328   1.00 42.61  ? 219 ALA B CB  1 
ATOM   5022  N N   . PHE B 1 220 ? 20.744  -17.624 0.682   1.00 40.25  ? 220 PHE B N   1 
ATOM   5023  C CA  . PHE B 1 220 ? 19.931  -16.440 0.428   1.00 39.06  ? 220 PHE B CA  1 
ATOM   5024  C C   . PHE B 1 220 ? 18.466  -16.727 0.774   1.00 38.35  ? 220 PHE B C   1 
ATOM   5025  O O   . PHE B 1 220 ? 17.807  -15.903 1.403   1.00 38.94  ? 220 PHE B O   1 
ATOM   5026  C CB  . PHE B 1 220 ? 20.097  -16.018 -1.025  1.00 37.94  ? 220 PHE B CB  1 
ATOM   5027  C CG  . PHE B 1 220 ? 19.368  -14.749 -1.400  1.00 40.07  ? 220 PHE B CG  1 
ATOM   5028  C CD1 . PHE B 1 220 ? 20.005  -13.530 -1.328  1.00 38.86  ? 220 PHE B CD1 1 
ATOM   5029  C CD2 . PHE B 1 220 ? 18.035  -14.775 -1.822  1.00 39.63  ? 220 PHE B CD2 1 
ATOM   5030  C CE1 . PHE B 1 220 ? 19.343  -12.365 -1.675  1.00 40.83  ? 220 PHE B CE1 1 
ATOM   5031  C CE2 . PHE B 1 220 ? 17.383  -13.604 -2.173  1.00 38.58  ? 220 PHE B CE2 1 
ATOM   5032  C CZ  . PHE B 1 220 ? 18.037  -12.407 -2.103  1.00 37.77  ? 220 PHE B CZ  1 
ATOM   5033  N N   . VAL B 1 221 ? 17.970  -17.907 0.378   1.00 39.85  ? 221 VAL B N   1 
ATOM   5034  C CA  . VAL B 1 221 ? 16.574  -18.281 0.625   1.00 41.22  ? 221 VAL B CA  1 
ATOM   5035  C C   . VAL B 1 221 ? 16.410  -18.792 2.064   1.00 43.12  ? 221 VAL B C   1 
ATOM   5036  O O   . VAL B 1 221 ? 15.408  -18.505 2.714   1.00 39.70  ? 221 VAL B O   1 
ATOM   5037  C CB  . VAL B 1 221 ? 16.083  -19.318 -0.390  1.00 43.12  ? 221 VAL B CB  1 
ATOM   5038  C CG1 . VAL B 1 221 ? 14.612  -19.642 -0.182  1.00 48.15  ? 221 VAL B CG1 1 
ATOM   5039  C CG2 . VAL B 1 221 ? 16.314  -18.851 -1.821  1.00 40.57  ? 221 VAL B CG2 1 
ATOM   5040  N N   . GLU B 1 222 ? 17.422  -19.517 2.564   1.00 46.40  ? 222 GLU B N   1 
ATOM   5041  C CA  . GLU B 1 222 ? 17.347  -20.166 3.876   1.00 45.46  ? 222 GLU B CA  1 
ATOM   5042  C C   . GLU B 1 222 ? 17.478  -19.148 5.012   1.00 38.83  ? 222 GLU B C   1 
ATOM   5043  O O   . GLU B 1 222 ? 17.231  -19.485 6.177   1.00 38.73  ? 222 GLU B O   1 
ATOM   5044  C CB  . GLU B 1 222 ? 18.454  -21.209 4.058   1.00 53.50  ? 222 GLU B CB  1 
ATOM   5045  C CG  . GLU B 1 222 ? 17.941  -22.633 4.226   1.00 63.52  ? 222 GLU B CG  1 
ATOM   5046  C CD  . GLU B 1 222 ? 19.040  -23.684 4.378   1.00 75.89  ? 222 GLU B CD  1 
ATOM   5047  O OE1 . GLU B 1 222 ? 19.915  -23.758 3.477   1.00 79.75  ? 222 GLU B OE1 1 
ATOM   5048  O OE2 . GLU B 1 222 ? 19.014  -24.443 5.389   1.00 77.26  ? 222 GLU B OE2 1 
ATOM   5049  N N   . HIS B 1 223 ? 17.942  -17.931 4.694   1.00 38.52  ? 223 HIS B N   1 
ATOM   5050  C CA  . HIS B 1 223 ? 18.361  -16.979 5.731   1.00 36.10  ? 223 HIS B CA  1 
ATOM   5051  C C   . HIS B 1 223 ? 17.179  -16.635 6.654   1.00 39.33  ? 223 HIS B C   1 
ATOM   5052  O O   . HIS B 1 223 ? 16.037  -16.495 6.200   1.00 42.45  ? 223 HIS B O   1 
ATOM   5053  C CB  . HIS B 1 223 ? 18.960  -15.723 5.102   1.00 35.92  ? 223 HIS B CB  1 
ATOM   5054  C CG  . HIS B 1 223 ? 19.894  -14.998 5.989   1.00 35.92  ? 223 HIS B CG  1 
ATOM   5055  N ND1 . HIS B 1 223 ? 19.482  -14.043 6.896   1.00 36.87  ? 223 HIS B ND1 1 
ATOM   5056  C CD2 . HIS B 1 223 ? 21.246  -15.097 6.118   1.00 35.96  ? 223 HIS B CD2 1 
ATOM   5057  C CE1 . HIS B 1 223 ? 20.551  -13.579 7.563   1.00 41.43  ? 223 HIS B CE1 1 
ATOM   5058  N NE2 . HIS B 1 223 ? 21.639  -14.204 7.092   1.00 38.78  ? 223 HIS B NE2 1 
ATOM   5059  N N   . PRO B 1 224 ? 17.411  -16.471 7.974   1.00 43.89  ? 224 PRO B N   1 
ATOM   5060  C CA  . PRO B 1 224 ? 16.326  -16.102 8.898   1.00 41.64  ? 224 PRO B CA  1 
ATOM   5061  C C   . PRO B 1 224 ? 15.782  -14.661 8.815   1.00 38.62  ? 224 PRO B C   1 
ATOM   5062  O O   . PRO B 1 224 ? 14.716  -14.390 9.322   1.00 43.24  ? 224 PRO B O   1 
ATOM   5063  C CB  . PRO B 1 224 ? 16.985  -16.395 10.277  1.00 43.92  ? 224 PRO B CB  1 
ATOM   5064  C CG  . PRO B 1 224 ? 18.478  -16.193 10.029  1.00 41.77  ? 224 PRO B CG  1 
ATOM   5065  C CD  . PRO B 1 224 ? 18.695  -16.744 8.659   1.00 40.64  ? 224 PRO B CD  1 
ATOM   5066  N N   . VAL B 1 225 ? 16.517  -13.742 8.191   1.00 38.84  ? 225 VAL B N   1 
ATOM   5067  C CA  . VAL B 1 225 ? 16.140  -12.319 8.229   1.00 41.04  ? 225 VAL B CA  1 
ATOM   5068  C C   . VAL B 1 225 ? 14.938  -12.044 7.315   1.00 42.99  ? 225 VAL B C   1 
ATOM   5069  O O   . VAL B 1 225 ? 14.005  -11.339 7.726   1.00 44.24  ? 225 VAL B O   1 
ATOM   5070  C CB  . VAL B 1 225 ? 17.308  -11.394 7.882   1.00 43.14  ? 225 VAL B CB  1 
ATOM   5071  C CG1 . VAL B 1 225 ? 16.842  -10.005 7.449   1.00 43.79  ? 225 VAL B CG1 1 
ATOM   5072  C CG2 . VAL B 1 225 ? 18.268  -11.297 9.035   1.00 41.34  ? 225 VAL B CG2 1 
ATOM   5073  N N   . PRO B 1 226 ? 14.947  -12.478 6.030   1.00 41.61  ? 226 PRO B N   1 
ATOM   5074  C CA  . PRO B 1 226 ? 13.923  -12.030 5.078   1.00 41.25  ? 226 PRO B CA  1 
ATOM   5075  C C   . PRO B 1 226 ? 12.542  -12.582 5.420   1.00 43.13  ? 226 PRO B C   1 
ATOM   5076  O O   . PRO B 1 226 ? 12.374  -13.782 5.560   1.00 46.33  ? 226 PRO B O   1 
ATOM   5077  C CB  . PRO B 1 226 ? 14.453  -12.560 3.726   1.00 38.61  ? 226 PRO B CB  1 
ATOM   5078  C CG  . PRO B 1 226 ? 15.269  -13.763 4.107   1.00 36.83  ? 226 PRO B CG  1 
ATOM   5079  C CD  . PRO B 1 226 ? 15.954  -13.348 5.404   1.00 39.24  ? 226 PRO B CD  1 
ATOM   5080  N N   . GLY B 1 227 ? 11.563  -11.684 5.541   1.00 43.19  ? 227 GLY B N   1 
ATOM   5081  C CA  . GLY B 1 227 ? 10.176  -12.067 5.801   1.00 40.22  ? 227 GLY B CA  1 
ATOM   5082  C C   . GLY B 1 227 ? 9.483   -12.644 4.562   1.00 42.22  ? 227 GLY B C   1 
ATOM   5083  O O   . GLY B 1 227 ? 8.567   -13.445 4.680   1.00 49.13  ? 227 GLY B O   1 
ATOM   5084  N N   . LEU B 1 228 ? 9.913   -12.216 3.377   1.00 46.34  ? 228 LEU B N   1 
ATOM   5085  C CA  . LEU B 1 228 ? 9.349   -12.714 2.127   1.00 43.97  ? 228 LEU B CA  1 
ATOM   5086  C C   . LEU B 1 228 ? 10.481  -12.920 1.109   1.00 42.43  ? 228 LEU B C   1 
ATOM   5087  O O   . LEU B 1 228 ? 11.438  -12.147 1.087   1.00 40.94  ? 228 LEU B O   1 
ATOM   5088  C CB  . LEU B 1 228 ? 8.308   -11.700 1.639   1.00 42.49  ? 228 LEU B CB  1 
ATOM   5089  C CG  . LEU B 1 228 ? 7.669   -11.976 0.280   1.00 47.90  ? 228 LEU B CG  1 
ATOM   5090  C CD1 . LEU B 1 228 ? 6.864   -13.285 0.312   1.00 47.36  ? 228 LEU B CD1 1 
ATOM   5091  C CD2 . LEU B 1 228 ? 6.798   -10.787 -0.147  1.00 47.52  ? 228 LEU B CD2 1 
ATOM   5092  N N   . VAL B 1 229 ? 10.344  -13.969 0.266   1.00 42.03  ? 229 VAL B N   1 
ATOM   5093  C CA  . VAL B 1 229 ? 11.211  -14.171 -0.888  1.00 42.84  ? 229 VAL B CA  1 
ATOM   5094  C C   . VAL B 1 229 ? 10.354  -14.248 -2.155  1.00 41.01  ? 229 VAL B C   1 
ATOM   5095  O O   . VAL B 1 229 ? 9.430   -15.057 -2.235  1.00 41.76  ? 229 VAL B O   1 
ATOM   5096  C CB  . VAL B 1 229 ? 12.069  -15.435 -0.720  1.00 50.14  ? 229 VAL B CB  1 
ATOM   5097  C CG1 . VAL B 1 229 ? 12.936  -15.709 -1.959  1.00 50.88  ? 229 VAL B CG1 1 
ATOM   5098  C CG2 . VAL B 1 229 ? 12.933  -15.349 0.530   1.00 50.14  ? 229 VAL B CG2 1 
ATOM   5099  N N   . THR B 1 230 ? 10.712  -13.433 -3.163  1.00 36.84  ? 230 THR B N   1 
ATOM   5100  C CA  . THR B 1 230 ? 9.956   -13.358 -4.411  1.00 39.43  ? 230 THR B CA  1 
ATOM   5101  C C   . THR B 1 230 ? 10.829  -13.856 -5.549  1.00 39.83  ? 230 THR B C   1 
ATOM   5102  O O   . THR B 1 230 ? 12.017  -13.586 -5.577  1.00 40.92  ? 230 THR B O   1 
ATOM   5103  C CB  . THR B 1 230 ? 9.474   -11.923 -4.666  1.00 39.49  ? 230 THR B CB  1 
ATOM   5104  O OG1 . THR B 1 230 ? 10.582  -11.165 -5.161  1.00 35.54  ? 230 THR B OG1 1 
ATOM   5105  C CG2 . THR B 1 230 ? 8.922   -11.276 -3.407  1.00 44.16  ? 230 THR B CG2 1 
ATOM   5106  N N   . PHE B 1 231 ? 10.209  -14.574 -6.491  1.00 43.50  ? 231 PHE B N   1 
ATOM   5107  C CA  . PHE B 1 231 ? 10.893  -15.075 -7.673  1.00 44.02  ? 231 PHE B CA  1 
ATOM   5108  C C   . PHE B 1 231 ? 9.918   -15.100 -8.848  1.00 43.75  ? 231 PHE B C   1 
ATOM   5109  O O   . PHE B 1 231 ? 8.817   -15.587 -8.724  1.00 51.55  ? 231 PHE B O   1 
ATOM   5110  C CB  . PHE B 1 231 ? 11.480  -16.473 -7.431  1.00 44.45  ? 231 PHE B CB  1 
ATOM   5111  C CG  . PHE B 1 231 ? 12.054  -17.105 -8.692  1.00 48.79  ? 231 PHE B CG  1 
ATOM   5112  C CD1 . PHE B 1 231 ? 13.245  -16.628 -9.255  1.00 49.76  ? 231 PHE B CD1 1 
ATOM   5113  C CD2 . PHE B 1 231 ? 11.383  -18.145 -9.344  1.00 48.95  ? 231 PHE B CD2 1 
ATOM   5114  C CE1 . PHE B 1 231 ? 13.749  -17.185 -10.436 1.00 51.68  ? 231 PHE B CE1 1 
ATOM   5115  C CE2 . PHE B 1 231 ? 11.887  -18.695 -10.520 1.00 49.07  ? 231 PHE B CE2 1 
ATOM   5116  C CZ  . PHE B 1 231 ? 13.059  -18.202 -11.076 1.00 47.07  ? 231 PHE B CZ  1 
ATOM   5117  N N   . THR B 1 232 ? 10.348  -14.567 -9.984  1.00 52.85  ? 232 THR B N   1 
ATOM   5118  C CA  . THR B 1 232 ? 9.637   -14.736 -11.251 1.00 62.05  ? 232 THR B CA  1 
ATOM   5119  C C   . THR B 1 232 ? 10.593  -15.368 -12.257 1.00 64.61  ? 232 THR B C   1 
ATOM   5120  O O   . THR B 1 232 ? 11.665  -14.825 -12.500 1.00 62.81  ? 232 THR B O   1 
ATOM   5121  C CB  . THR B 1 232 ? 9.139   -13.377 -11.771 1.00 65.77  ? 232 THR B CB  1 
ATOM   5122  O OG1 . THR B 1 232 ? 8.338   -12.755 -10.764 1.00 66.74  ? 232 THR B OG1 1 
ATOM   5123  C CG2 . THR B 1 232 ? 8.346   -13.515 -13.061 1.00 66.41  ? 232 THR B CG2 1 
ATOM   5124  N N   . GLY B 1 233 ? 10.187  -16.491 -12.873 1.00 67.66  ? 233 GLY B N   1 
ATOM   5125  C CA  . GLY B 1 233 ? 10.976  -17.085 -13.954 1.00 63.47  ? 233 GLY B CA  1 
ATOM   5126  C C   . GLY B 1 233 ? 10.687  -18.575 -14.158 1.00 63.58  ? 233 GLY B C   1 
ATOM   5127  O O   . GLY B 1 233 ? 9.539   -18.997 -14.182 1.00 64.10  ? 233 GLY B O   1 
ATOM   5128  N N   . SER B 1 234 ? 11.764  -19.343 -14.336 1.00 69.92  ? 234 SER B N   1 
ATOM   5129  C CA  . SER B 1 234 ? 11.712  -20.737 -14.755 1.00 71.85  ? 234 SER B CA  1 
ATOM   5130  C C   . SER B 1 234 ? 11.069  -21.614 -13.669 1.00 65.78  ? 234 SER B C   1 
ATOM   5131  O O   . SER B 1 234 ? 11.268  -21.385 -12.484 1.00 67.59  ? 234 SER B O   1 
ATOM   5132  C CB  . SER B 1 234 ? 13.124  -21.224 -15.096 1.00 78.43  ? 234 SER B CB  1 
ATOM   5133  O OG  . SER B 1 234 ? 13.142  -22.618 -15.350 1.00 90.22  ? 234 SER B OG  1 
ATOM   5134  N N   . THR B 1 235 ? 10.350  -22.660 -14.103 1.00 62.45  ? 235 THR B N   1 
ATOM   5135  C CA  . THR B 1 235 ? 9.615   -23.537 -13.195 1.00 64.32  ? 235 THR B CA  1 
ATOM   5136  C C   . THR B 1 235 ? 10.592  -24.360 -12.352 1.00 66.04  ? 235 THR B C   1 
ATOM   5137  O O   . THR B 1 235 ? 10.426  -24.444 -11.144 1.00 71.52  ? 235 THR B O   1 
ATOM   5138  C CB  . THR B 1 235 ? 8.641   -24.439 -13.969 1.00 63.31  ? 235 THR B CB  1 
ATOM   5139  O OG1 . THR B 1 235 ? 7.684   -23.571 -14.572 1.00 65.47  ? 235 THR B OG1 1 
ATOM   5140  C CG2 . THR B 1 235 ? 7.918   -25.432 -13.069 1.00 58.19  ? 235 THR B CG2 1 
ATOM   5141  N N   . PRO B 1 236 ? 11.601  -25.041 -12.944 1.00 78.59  ? 236 PRO B N   1 
ATOM   5142  C CA  . PRO B 1 236 ? 12.549  -25.825 -12.139 1.00 76.94  ? 236 PRO B CA  1 
ATOM   5143  C C   . PRO B 1 236 ? 13.279  -24.998 -11.064 1.00 68.76  ? 236 PRO B C   1 
ATOM   5144  O O   . PRO B 1 236 ? 13.462  -25.463 -9.937  1.00 67.45  ? 236 PRO B O   1 
ATOM   5145  C CB  . PRO B 1 236 ? 13.523  -26.432 -13.200 1.00 79.27  ? 236 PRO B CB  1 
ATOM   5146  C CG  . PRO B 1 236 ? 13.298  -25.581 -14.456 1.00 81.73  ? 236 PRO B CG  1 
ATOM   5147  C CD  . PRO B 1 236 ? 11.835  -25.173 -14.394 1.00 80.61  ? 236 PRO B CD  1 
ATOM   5148  N N   . VAL B 1 237 ? 13.644  -23.758 -11.405 1.00 58.68  ? 237 VAL B N   1 
ATOM   5149  C CA  . VAL B 1 237 ? 14.295  -22.858 -10.453 1.00 63.95  ? 237 VAL B CA  1 
ATOM   5150  C C   . VAL B 1 237 ? 13.320  -22.551 -9.300  1.00 65.59  ? 237 VAL B C   1 
ATOM   5151  O O   . VAL B 1 237 ? 13.689  -22.631 -8.125  1.00 60.50  ? 237 VAL B O   1 
ATOM   5152  C CB  . VAL B 1 237 ? 14.783  -21.554 -11.128 1.00 62.84  ? 237 VAL B CB  1 
ATOM   5153  C CG1 . VAL B 1 237 ? 15.506  -20.641 -10.150 1.00 59.56  ? 237 VAL B CG1 1 
ATOM   5154  C CG2 . VAL B 1 237 ? 15.669  -21.839 -12.336 1.00 63.67  ? 237 VAL B CG2 1 
ATOM   5155  N N   . GLY B 1 238 ? 12.082  -22.180 -9.652  1.00 60.71  ? 238 GLY B N   1 
ATOM   5156  C CA  . GLY B 1 238 ? 11.069  -21.846 -8.669  1.00 58.34  ? 238 GLY B CA  1 
ATOM   5157  C C   . GLY B 1 238 ? 10.782  -23.025 -7.749  1.00 58.48  ? 238 GLY B C   1 
ATOM   5158  O O   . GLY B 1 238 ? 10.576  -22.839 -6.550  1.00 57.18  ? 238 GLY B O   1 
ATOM   5159  N N   . ARG B 1 239 ? 10.777  -24.236 -8.329  1.00 54.21  ? 239 ARG B N   1 
ATOM   5160  C CA  . ARG B 1 239 ? 10.609  -25.467 -7.563  1.00 59.51  ? 239 ARG B CA  1 
ATOM   5161  C C   . ARG B 1 239 ? 11.735  -25.582 -6.519  1.00 58.02  ? 239 ARG B C   1 
ATOM   5162  O O   . ARG B 1 239 ? 11.488  -25.908 -5.360  1.00 50.50  ? 239 ARG B O   1 
ATOM   5163  C CB  . ARG B 1 239 ? 10.626  -26.667 -8.514  1.00 69.08  ? 239 ARG B CB  1 
ATOM   5164  C CG  . ARG B 1 239 ? 9.513   -27.680 -8.281  1.00 84.00  ? 239 ARG B CG  1 
ATOM   5165  C CD  . ARG B 1 239 ? 9.671   -28.912 -9.209  1.00 89.70  ? 239 ARG B CD  1 
ATOM   5166  N NE  . ARG B 1 239 ? 8.465   -29.180 -10.004 1.00 89.77  ? 239 ARG B NE  1 
ATOM   5167  C CZ  . ARG B 1 239 ? 8.425   -29.270 -11.350 1.00 100.12 ? 239 ARG B CZ  1 
ATOM   5168  N NH1 . ARG B 1 239 ? 9.546   -29.232 -12.071 1.00 100.26 ? 239 ARG B NH1 1 
ATOM   5169  N NH2 . ARG B 1 239 ? 7.265   -29.416 -11.961 1.00 96.50  ? 239 ARG B NH2 1 
ATOM   5170  N N   . ASN B 1 240 ? 12.968  -25.294 -6.954  1.00 59.67  ? 240 ASN B N   1 
ATOM   5171  C CA  . ASN B 1 240 ? 14.135  -25.351 -6.095  1.00 57.93  ? 240 ASN B CA  1 
ATOM   5172  C C   . ASN B 1 240 ? 13.983  -24.332 -4.957  1.00 53.98  ? 240 ASN B C   1 
ATOM   5173  O O   . ASN B 1 240 ? 14.203  -24.659 -3.788  1.00 44.57  ? 240 ASN B O   1 
ATOM   5174  C CB  . ASN B 1 240 ? 15.418  -25.146 -6.909  1.00 67.33  ? 240 ASN B CB  1 
ATOM   5175  C CG  . ASN B 1 240 ? 16.683  -25.302 -6.083  1.00 75.58  ? 240 ASN B CG  1 
ATOM   5176  O OD1 . ASN B 1 240 ? 17.705  -24.694 -6.406  1.00 78.81  ? 240 ASN B OD1 1 
ATOM   5177  N ND2 . ASN B 1 240 ? 16.632  -26.071 -5.001  1.00 81.85  ? 240 ASN B ND2 1 
ATOM   5178  N N   . ILE B 1 241 ? 13.617  -23.089 -5.307  1.00 49.32  ? 241 ILE B N   1 
ATOM   5179  C CA  . ILE B 1 241 ? 13.492  -22.038 -4.309  1.00 47.04  ? 241 ILE B CA  1 
ATOM   5180  C C   . ILE B 1 241 ? 12.407  -22.424 -3.300  1.00 45.26  ? 241 ILE B C   1 
ATOM   5181  O O   . ILE B 1 241 ? 12.581  -22.243 -2.095  1.00 45.72  ? 241 ILE B O   1 
ATOM   5182  C CB  . ILE B 1 241 ? 13.220  -20.681 -4.974  1.00 42.40  ? 241 ILE B CB  1 
ATOM   5183  C CG1 . ILE B 1 241 ? 14.488  -20.122 -5.598  1.00 41.88  ? 241 ILE B CG1 1 
ATOM   5184  C CG2 . ILE B 1 241 ? 12.590  -19.688 -3.986  1.00 38.65  ? 241 ILE B CG2 1 
ATOM   5185  C CD1 . ILE B 1 241 ? 14.238  -19.277 -6.833  1.00 45.38  ? 241 ILE B CD1 1 
ATOM   5186  N N   . GLY B 1 242 ? 11.296  -22.963 -3.807  1.00 47.15  ? 242 GLY B N   1 
ATOM   5187  C CA  . GLY B 1 242 ? 10.157  -23.313 -2.973  1.00 49.32  ? 242 GLY B CA  1 
ATOM   5188  C C   . GLY B 1 242 ? 10.519  -24.392 -1.954  1.00 52.51  ? 242 GLY B C   1 
ATOM   5189  O O   . GLY B 1 242 ? 10.098  -24.323 -0.778  1.00 48.77  ? 242 GLY B O   1 
ATOM   5190  N N   . ARG B 1 243 ? 11.328  -25.362 -2.402  1.00 48.93  ? 243 ARG B N   1 
ATOM   5191  C CA  . ARG B 1 243 ? 11.711  -26.490 -1.571  1.00 63.74  ? 243 ARG B CA  1 
ATOM   5192  C C   . ARG B 1 243 ? 12.595  -26.008 -0.419  1.00 72.03  ? 243 ARG B C   1 
ATOM   5193  O O   . ARG B 1 243 ? 12.380  -26.387 0.730   1.00 72.50  ? 243 ARG B O   1 
ATOM   5194  C CB  . ARG B 1 243 ? 12.425  -27.539 -2.422  1.00 66.17  ? 243 ARG B CB  1 
ATOM   5195  C CG  . ARG B 1 243 ? 13.237  -28.560 -1.639  1.00 72.14  ? 243 ARG B CG  1 
ATOM   5196  C CD  . ARG B 1 243 ? 13.879  -29.544 -2.591  1.00 78.37  ? 243 ARG B CD  1 
ATOM   5197  N NE  . ARG B 1 243 ? 12.956  -29.887 -3.686  1.00 89.16  ? 243 ARG B NE  1 
ATOM   5198  C CZ  . ARG B 1 243 ? 13.131  -29.586 -4.987  1.00 95.60  ? 243 ARG B CZ  1 
ATOM   5199  N NH1 . ARG B 1 243 ? 14.264  -29.038 -5.399  1.00 99.23  ? 243 ARG B NH1 1 
ATOM   5200  N NH2 . ARG B 1 243 ? 12.172  -29.858 -5.870  1.00 94.92  ? 243 ARG B NH2 1 
ATOM   5201  N N   . ILE B 1 244 ? 13.597  -25.179 -0.751  1.00 70.33  ? 244 ILE B N   1 
ATOM   5202  C CA  . ILE B 1 244 ? 14.531  -24.660 0.232   1.00 65.76  ? 244 ILE B CA  1 
ATOM   5203  C C   . ILE B 1 244 ? 13.777  -23.795 1.244   1.00 68.09  ? 244 ILE B C   1 
ATOM   5204  O O   . ILE B 1 244 ? 14.066  -23.853 2.435   1.00 62.33  ? 244 ILE B O   1 
ATOM   5205  C CB  . ILE B 1 244 ? 15.664  -23.880 -0.449  1.00 68.49  ? 244 ILE B CB  1 
ATOM   5206  C CG1 . ILE B 1 244 ? 16.544  -24.796 -1.288  1.00 66.37  ? 244 ILE B CG1 1 
ATOM   5207  C CG2 . ILE B 1 244 ? 16.482  -23.100 0.580   1.00 72.32  ? 244 ILE B CG2 1 
ATOM   5208  C CD1 . ILE B 1 244 ? 17.181  -24.111 -2.478  1.00 70.31  ? 244 ILE B CD1 1 
ATOM   5209  N N   . ALA B 1 245 ? 12.799  -23.007 0.758   1.00 64.40  ? 245 ALA B N   1 
ATOM   5210  C CA  . ALA B 1 245 ? 12.027  -22.120 1.618   1.00 69.21  ? 245 ALA B CA  1 
ATOM   5211  C C   . ALA B 1 245 ? 11.329  -22.929 2.718   1.00 79.08  ? 245 ALA B C   1 
ATOM   5212  O O   . ALA B 1 245 ? 11.533  -22.670 3.897   1.00 96.60  ? 245 ALA B O   1 
ATOM   5213  C CB  . ALA B 1 245 ? 11.040  -21.316 0.790   1.00 69.17  ? 245 ALA B CB  1 
ATOM   5214  N N   . SER B 1 246 ? 10.521  -23.921 2.320   1.00 94.57  ? 246 SER B N   1 
ATOM   5215  C CA  . SER B 1 246 ? 9.789   -24.744 3.279   1.00 91.31  ? 246 SER B CA  1 
ATOM   5216  C C   . SER B 1 246 ? 10.734  -25.763 3.944   1.00 90.12  ? 246 SER B C   1 
ATOM   5217  O O   . SER B 1 246 ? 10.612  -26.038 5.127   1.00 91.14  ? 246 SER B O   1 
ATOM   5218  C CB  . SER B 1 246 ? 8.618   -25.408 2.630   1.00 83.89  ? 246 SER B CB  1 
ATOM   5219  O OG  . SER B 1 246 ? 7.883   -24.463 1.854   1.00 79.81  ? 246 SER B OG  1 
ATOM   5220  N N   . GLY B 1 247 ? 11.709  -26.265 3.186   1.00 96.17  ? 247 GLY B N   1 
ATOM   5221  C CA  . GLY B 1 247 ? 12.621  -27.297 3.677   1.00 96.93  ? 247 GLY B CA  1 
ATOM   5222  C C   . GLY B 1 247 ? 13.582  -26.770 4.749   1.00 99.33  ? 247 GLY B C   1 
ATOM   5223  O O   . GLY B 1 247 ? 14.000  -27.518 5.629   1.00 109.34 ? 247 GLY B O   1 
ATOM   5224  N N   . GLY B 1 248 ? 13.927  -25.481 4.670   1.00 99.40  ? 248 GLY B N   1 
ATOM   5225  C CA  . GLY B 1 248 ? 14.960  -24.913 5.533   1.00 91.40  ? 248 GLY B CA  1 
ATOM   5226  C C   . GLY B 1 248 ? 14.497  -24.825 6.991   1.00 85.02  ? 248 GLY B C   1 
ATOM   5227  O O   . GLY B 1 248 ? 13.300  -24.926 7.282   1.00 82.50  ? 248 GLY B O   1 
ATOM   5228  N N   . ALA B 1 249 ? 15.465  -24.623 7.895   1.00 75.27  ? 249 ALA B N   1 
ATOM   5229  C CA  . ALA B 1 249 ? 15.190  -24.491 9.316   1.00 73.67  ? 249 ALA B CA  1 
ATOM   5230  C C   . ALA B 1 249 ? 14.227  -23.337 9.557   1.00 73.92  ? 249 ALA B C   1 
ATOM   5231  O O   . ALA B 1 249 ? 13.293  -23.466 10.333  1.00 73.54  ? 249 ALA B O   1 
ATOM   5232  C CB  . ALA B 1 249 ? 16.477  -24.292 10.075  1.00 74.15  ? 249 ALA B CB  1 
ATOM   5233  N N   . HIS B 1 250 ? 14.483  -22.202 8.892   1.00 78.84  ? 250 HIS B N   1 
ATOM   5234  C CA  . HIS B 1 250 ? 13.632  -21.027 9.010   1.00 77.42  ? 250 HIS B CA  1 
ATOM   5235  C C   . HIS B 1 250 ? 12.574  -21.070 7.912   1.00 80.52  ? 250 HIS B C   1 
ATOM   5236  O O   . HIS B 1 250 ? 12.894  -21.332 6.754   1.00 84.83  ? 250 HIS B O   1 
ATOM   5237  C CB  . HIS B 1 250 ? 14.477  -19.749 8.963   1.00 75.16  ? 250 HIS B CB  1 
ATOM   5238  C CG  . HIS B 1 250 ? 15.741  -19.850 9.747   1.00 75.75  ? 250 HIS B CG  1 
ATOM   5239  N ND1 . HIS B 1 250 ? 15.753  -20.068 11.112  1.00 73.59  ? 250 HIS B ND1 1 
ATOM   5240  C CD2 . HIS B 1 250 ? 17.032  -19.843 9.361   1.00 84.03  ? 250 HIS B CD2 1 
ATOM   5241  C CE1 . HIS B 1 250 ? 17.009  -20.160 11.534  1.00 73.75  ? 250 HIS B CE1 1 
ATOM   5242  N NE2 . HIS B 1 250 ? 17.805  -20.023 10.492  1.00 83.33  ? 250 HIS B NE2 1 
ATOM   5243  N N   . LEU B 1 251 ? 11.307  -20.801 8.293   1.00 80.77  ? 251 LEU B N   1 
ATOM   5244  C CA  . LEU B 1 251 ? 10.186  -20.814 7.348   1.00 75.22  ? 251 LEU B CA  1 
ATOM   5245  C C   . LEU B 1 251 ? 9.782   -19.383 7.020   1.00 66.70  ? 251 LEU B C   1 
ATOM   5246  O O   . LEU B 1 251 ? 9.592   -18.566 7.914   1.00 67.47  ? 251 LEU B O   1 
ATOM   5247  C CB  . LEU B 1 251 ? 8.995   -21.601 7.897   1.00 73.94  ? 251 LEU B CB  1 
ATOM   5248  C CG  . LEU B 1 251 ? 9.204   -23.108 8.078   1.00 86.07  ? 251 LEU B CG  1 
ATOM   5249  C CD1 . LEU B 1 251 ? 7.892   -23.843 7.892   1.00 82.89  ? 251 LEU B CD1 1 
ATOM   5250  C CD2 . LEU B 1 251 ? 10.276  -23.665 7.133   1.00 96.92  ? 251 LEU B CD2 1 
ATOM   5251  N N   . LYS B 1 252 ? 9.672   -19.094 5.717   1.00 63.51  ? 252 LYS B N   1 
ATOM   5252  C CA  . LYS B 1 252 ? 9.177   -17.807 5.244   1.00 56.55  ? 252 LYS B CA  1 
ATOM   5253  C C   . LYS B 1 252 ? 8.138   -18.049 4.166   1.00 47.35  ? 252 LYS B C   1 
ATOM   5254  O O   . LYS B 1 252 ? 8.137   -19.097 3.540   1.00 37.38  ? 252 LYS B O   1 
ATOM   5255  C CB  . LYS B 1 252 ? 10.319  -16.917 4.714   1.00 61.30  ? 252 LYS B CB  1 
ATOM   5256  C CG  . LYS B 1 252 ? 11.351  -17.619 3.800   1.00 63.76  ? 252 LYS B CG  1 
ATOM   5257  C CD  . LYS B 1 252 ? 12.786  -17.128 4.008   1.00 69.29  ? 252 LYS B CD  1 
ATOM   5258  C CE  . LYS B 1 252 ? 13.421  -17.665 5.245   1.00 66.85  ? 252 LYS B CE  1 
ATOM   5259  N NZ  . LYS B 1 252 ? 13.395  -19.129 5.253   1.00 79.42  ? 252 LYS B NZ  1 
ATOM   5260  N N   . HIS B 1 253 ? 7.269   -17.042 3.952   1.00 50.77  ? 253 HIS B N   1 
ATOM   5261  C CA  . HIS B 1 253 ? 6.424   -16.968 2.773   1.00 53.14  ? 253 HIS B CA  1 
ATOM   5262  C C   . HIS B 1 253 ? 7.299   -16.818 1.533   1.00 49.31  ? 253 HIS B C   1 
ATOM   5263  O O   . HIS B 1 253 ? 8.283   -16.081 1.535   1.00 50.57  ? 253 HIS B O   1 
ATOM   5264  C CB  . HIS B 1 253 ? 5.444   -15.783 2.869   1.00 61.61  ? 253 HIS B CB  1 
ATOM   5265  C CG  . HIS B 1 253 ? 4.216   -16.053 3.676   1.00 79.77  ? 253 HIS B CG  1 
ATOM   5266  N ND1 . HIS B 1 253 ? 3.763   -15.198 4.665   1.00 83.96  ? 253 HIS B ND1 1 
ATOM   5267  C CD2 . HIS B 1 253 ? 3.350   -17.080 3.650   1.00 86.47  ? 253 HIS B CD2 1 
ATOM   5268  C CE1 . HIS B 1 253 ? 2.670   -15.703 5.216   1.00 76.47  ? 253 HIS B CE1 1 
ATOM   5269  N NE2 . HIS B 1 253 ? 2.393   -16.838 4.609   1.00 87.56  ? 253 HIS B NE2 1 
ATOM   5270  N N   . VAL B 1 254 ? 6.886   -17.462 0.461   1.00 51.29  ? 254 VAL B N   1 
ATOM   5271  C CA  . VAL B 1 254 ? 7.544   -17.302 -0.818  1.00 51.85  ? 254 VAL B CA  1 
ATOM   5272  C C   . VAL B 1 254 ? 6.490   -16.960 -1.873  1.00 49.88  ? 254 VAL B C   1 
ATOM   5273  O O   . VAL B 1 254 ? 5.414   -17.510 -1.869  1.00 59.97  ? 254 VAL B O   1 
ATOM   5274  C CB  . VAL B 1 254 ? 8.344   -18.574 -1.162  1.00 55.20  ? 254 VAL B CB  1 
ATOM   5275  C CG1 . VAL B 1 254 ? 7.469   -19.668 -1.745  1.00 61.62  ? 254 VAL B CG1 1 
ATOM   5276  C CG2 . VAL B 1 254 ? 9.504   -18.268 -2.085  1.00 66.23  ? 254 VAL B CG2 1 
ATOM   5277  N N   . ALA B 1 255 ? 6.796   -15.988 -2.724  1.00 49.05  ? 255 ALA B N   1 
ATOM   5278  C CA  . ALA B 1 255 ? 5.929   -15.631 -3.841  1.00 47.09  ? 255 ALA B CA  1 
ATOM   5279  C C   . ALA B 1 255 ? 6.580   -16.066 -5.167  1.00 54.38  ? 255 ALA B C   1 
ATOM   5280  O O   . ALA B 1 255 ? 7.564   -15.471 -5.609  1.00 54.47  ? 255 ALA B O   1 
ATOM   5281  C CB  . ALA B 1 255 ? 5.656   -14.150 -3.826  1.00 41.53  ? 255 ALA B CB  1 
ATOM   5282  N N   . LEU B 1 256 ? 6.018   -17.111 -5.786  1.00 53.65  ? 256 LEU B N   1 
ATOM   5283  C CA  . LEU B 1 256 ? 6.582   -17.698 -6.987  1.00 49.82  ? 256 LEU B CA  1 
ATOM   5284  C C   . LEU B 1 256 ? 5.643   -17.449 -8.158  1.00 52.89  ? 256 LEU B C   1 
ATOM   5285  O O   . LEU B 1 256 ? 4.497   -17.885 -8.145  1.00 53.77  ? 256 LEU B O   1 
ATOM   5286  C CB  . LEU B 1 256 ? 6.794   -19.184 -6.747  1.00 56.44  ? 256 LEU B CB  1 
ATOM   5287  C CG  . LEU B 1 256 ? 7.797   -19.558 -5.650  1.00 62.46  ? 256 LEU B CG  1 
ATOM   5288  C CD1 . LEU B 1 256 ? 7.710   -21.042 -5.364  1.00 63.65  ? 256 LEU B CD1 1 
ATOM   5289  C CD2 . LEU B 1 256 ? 9.230   -19.171 -6.034  1.00 63.07  ? 256 LEU B CD2 1 
ATOM   5290  N N   . GLU B 1 257 ? 6.143   -16.714 -9.150  1.00 56.62  ? 257 GLU B N   1 
ATOM   5291  C CA  . GLU B 1 257 ? 5.438   -16.467 -10.401 1.00 59.85  ? 257 GLU B CA  1 
ATOM   5292  C C   . GLU B 1 257 ? 6.147   -17.266 -11.501 1.00 57.06  ? 257 GLU B C   1 
ATOM   5293  O O   . GLU B 1 257 ? 7.195   -16.841 -11.998 1.00 67.02  ? 257 GLU B O   1 
ATOM   5294  C CB  . GLU B 1 257 ? 5.481   -14.951 -10.675 1.00 72.55  ? 257 GLU B CB  1 
ATOM   5295  C CG  . GLU B 1 257 ? 4.184   -14.357 -11.213 1.00 88.31  ? 257 GLU B CG  1 
ATOM   5296  C CD  . GLU B 1 257 ? 3.067   -14.300 -10.189 1.00 108.24 ? 257 GLU B CD  1 
ATOM   5297  O OE1 . GLU B 1 257 ? 1.915   -14.567 -10.587 1.00 113.89 ? 257 GLU B OE1 1 
ATOM   5298  O OE2 . GLU B 1 257 ? 3.348   -14.023 -8.987  1.00 120.67 ? 257 GLU B OE2 1 
ATOM   5299  N N   . LEU B 1 258 ? 5.605   -18.452 -11.834 1.00 53.71  ? 258 LEU B N   1 
ATOM   5300  C CA  . LEU B 1 258 ? 6.340   -19.443 -12.623 1.00 57.00  ? 258 LEU B CA  1 
ATOM   5301  C C   . LEU B 1 258 ? 5.831   -19.477 -14.062 1.00 60.43  ? 258 LEU B C   1 
ATOM   5302  O O   . LEU B 1 258 ? 4.650   -19.727 -14.305 1.00 56.89  ? 258 LEU B O   1 
ATOM   5303  C CB  . LEU B 1 258 ? 6.238   -20.813 -11.969 1.00 51.94  ? 258 LEU B CB  1 
ATOM   5304  C CG  . LEU B 1 258 ? 7.044   -20.982 -10.687 1.00 55.31  ? 258 LEU B CG  1 
ATOM   5305  C CD1 . LEU B 1 258 ? 7.152   -22.439 -10.280 1.00 55.51  ? 258 LEU B CD1 1 
ATOM   5306  C CD2 . LEU B 1 258 ? 8.428   -20.358 -10.850 1.00 56.70  ? 258 LEU B CD2 1 
ATOM   5307  N N   . GLY B 1 259 ? 6.773   -19.294 -15.012 1.00 75.04  ? 259 GLY B N   1 
ATOM   5308  C CA  . GLY B 1 259 ? 6.479   -19.324 -16.436 1.00 76.28  ? 259 GLY B CA  1 
ATOM   5309  C C   . GLY B 1 259 ? 6.006   -20.703 -16.869 1.00 76.93  ? 259 GLY B C   1 
ATOM   5310  O O   . GLY B 1 259 ? 6.376   -21.714 -16.272 1.00 85.65  ? 259 GLY B O   1 
ATOM   5311  N N   . GLY B 1 260 ? 5.153   -20.728 -17.879 1.00 76.13  ? 260 GLY B N   1 
ATOM   5312  C CA  . GLY B 1 260 ? 4.573   -21.966 -18.350 1.00 77.74  ? 260 GLY B CA  1 
ATOM   5313  C C   . GLY B 1 260 ? 4.298   -21.898 -19.832 1.00 72.85  ? 260 GLY B C   1 
ATOM   5314  O O   . GLY B 1 260 ? 4.425   -20.843 -20.440 1.00 79.01  ? 260 GLY B O   1 
ATOM   5315  N N   . ASN B 1 261 ? 3.916   -23.029 -20.403 1.00 67.04  ? 261 ASN B N   1 
ATOM   5316  C CA  . ASN B 1 261 ? 3.425   -23.054 -21.762 1.00 70.33  ? 261 ASN B CA  1 
ATOM   5317  C C   . ASN B 1 261 ? 2.035   -22.405 -21.798 1.00 66.21  ? 261 ASN B C   1 
ATOM   5318  O O   . ASN B 1 261 ? 1.075   -22.951 -21.258 1.00 62.43  ? 261 ASN B O   1 
ATOM   5319  C CB  . ASN B 1 261 ? 3.424   -24.467 -22.330 1.00 68.83  ? 261 ASN B CB  1 
ATOM   5320  C CG  . ASN B 1 261 ? 3.438   -24.453 -23.835 1.00 70.92  ? 261 ASN B CG  1 
ATOM   5321  O OD1 . ASN B 1 261 ? 2.446   -24.060 -24.458 1.00 67.39  ? 261 ASN B OD1 1 
ATOM   5322  N ND2 . ASN B 1 261 ? 4.547   -24.860 -24.439 1.00 77.64  ? 261 ASN B ND2 1 
ATOM   5323  N N   . SER B 1 262 ? 1.953   -21.229 -22.435 1.00 63.68  ? 262 SER B N   1 
ATOM   5324  C CA  . SER B 1 262 ? 0.725   -20.446 -22.487 1.00 60.33  ? 262 SER B CA  1 
ATOM   5325  C C   . SER B 1 262 ? 0.042   -20.625 -23.847 1.00 53.53  ? 262 SER B C   1 
ATOM   5326  O O   . SER B 1 262 ? 0.665   -20.412 -24.878 1.00 50.37  ? 262 SER B O   1 
ATOM   5327  C CB  . SER B 1 262 ? 1.009   -19.012 -22.212 1.00 58.99  ? 262 SER B CB  1 
ATOM   5328  O OG  . SER B 1 262 ? 1.154   -18.792 -20.817 1.00 63.65  ? 262 SER B OG  1 
ATOM   5329  N N   . PRO B 1 263 ? -1.262  -20.996 -23.883 1.00 47.98  ? 263 PRO B N   1 
ATOM   5330  C CA  . PRO B 1 263 ? -1.954  -21.274 -25.138 1.00 47.44  ? 263 PRO B CA  1 
ATOM   5331  C C   . PRO B 1 263 ? -2.581  -20.044 -25.817 1.00 45.55  ? 263 PRO B C   1 
ATOM   5332  O O   . PRO B 1 263 ? -3.250  -19.242 -25.178 1.00 45.36  ? 263 PRO B O   1 
ATOM   5333  C CB  . PRO B 1 263 ? -3.014  -22.288 -24.695 1.00 46.77  ? 263 PRO B CB  1 
ATOM   5334  C CG  . PRO B 1 263 ? -3.365  -21.873 -23.270 1.00 49.56  ? 263 PRO B CG  1 
ATOM   5335  C CD  . PRO B 1 263 ? -2.140  -21.131 -22.719 1.00 49.88  ? 263 PRO B CD  1 
ATOM   5336  N N   . PHE B 1 264 ? -2.338  -19.929 -27.124 1.00 46.94  ? 264 PHE B N   1 
ATOM   5337  C CA  . PHE B 1 264 ? -2.975  -18.939 -27.975 1.00 46.46  ? 264 PHE B CA  1 
ATOM   5338  C C   . PHE B 1 264 ? -3.986  -19.648 -28.876 1.00 48.53  ? 264 PHE B C   1 
ATOM   5339  O O   . PHE B 1 264 ? -3.600  -20.483 -29.692 1.00 53.54  ? 264 PHE B O   1 
ATOM   5340  C CB  . PHE B 1 264 ? -1.882  -18.252 -28.791 1.00 48.63  ? 264 PHE B CB  1 
ATOM   5341  C CG  . PHE B 1 264 ? -2.354  -17.088 -29.654 1.00 59.71  ? 264 PHE B CG  1 
ATOM   5342  C CD1 . PHE B 1 264 ? -2.986  -17.303 -30.882 1.00 54.28  ? 264 PHE B CD1 1 
ATOM   5343  C CD2 . PHE B 1 264 ? -2.147  -15.775 -29.244 1.00 62.41  ? 264 PHE B CD2 1 
ATOM   5344  C CE1 . PHE B 1 264 ? -3.408  -16.238 -31.648 1.00 53.86  ? 264 PHE B CE1 1 
ATOM   5345  C CE2 . PHE B 1 264 ? -2.567  -14.717 -30.022 1.00 61.75  ? 264 PHE B CE2 1 
ATOM   5346  C CZ  . PHE B 1 264 ? -3.208  -14.950 -31.214 1.00 58.59  ? 264 PHE B CZ  1 
ATOM   5347  N N   . VAL B 1 265 ? -5.277  -19.341 -28.689 1.00 48.81  ? 265 VAL B N   1 
ATOM   5348  C CA  . VAL B 1 265 ? -6.352  -20.123 -29.285 1.00 48.93  ? 265 VAL B CA  1 
ATOM   5349  C C   . VAL B 1 265 ? -7.060  -19.274 -30.340 1.00 50.75  ? 265 VAL B C   1 
ATOM   5350  O O   . VAL B 1 265 ? -7.542  -18.186 -30.043 1.00 44.61  ? 265 VAL B O   1 
ATOM   5351  C CB  . VAL B 1 265 ? -7.369  -20.646 -28.259 1.00 48.02  ? 265 VAL B CB  1 
ATOM   5352  C CG1 . VAL B 1 265 ? -8.438  -21.500 -28.939 1.00 48.72  ? 265 VAL B CG1 1 
ATOM   5353  C CG2 . VAL B 1 265 ? -6.702  -21.424 -27.121 1.00 47.63  ? 265 VAL B CG2 1 
ATOM   5354  N N   . VAL B 1 266 ? -7.165  -19.823 -31.560 1.00 50.79  ? 266 VAL B N   1 
ATOM   5355  C CA  . VAL B 1 266 ? -7.890  -19.180 -32.643 1.00 53.39  ? 266 VAL B CA  1 
ATOM   5356  C C   . VAL B 1 266 ? -9.079  -20.055 -33.018 1.00 51.60  ? 266 VAL B C   1 
ATOM   5357  O O   . VAL B 1 266 ? -8.903  -21.120 -33.585 1.00 47.97  ? 266 VAL B O   1 
ATOM   5358  C CB  . VAL B 1 266 ? -6.978  -18.943 -33.857 1.00 56.09  ? 266 VAL B CB  1 
ATOM   5359  C CG1 . VAL B 1 266 ? -7.645  -18.047 -34.881 1.00 56.03  ? 266 VAL B CG1 1 
ATOM   5360  C CG2 . VAL B 1 266 ? -5.627  -18.368 -33.452 1.00 55.91  ? 266 VAL B CG2 1 
ATOM   5361  N N   . LEU B 1 267 ? -10.285 -19.586 -32.683 1.00 50.69  ? 267 LEU B N   1 
ATOM   5362  C CA  . LEU B 1 267 ? -11.506 -20.313 -32.968 1.00 53.49  ? 267 LEU B CA  1 
ATOM   5363  C C   . LEU B 1 267 ? -11.923 -20.078 -34.425 1.00 58.48  ? 267 LEU B C   1 
ATOM   5364  O O   . LEU B 1 267 ? -11.325 -19.255 -35.129 1.00 57.08  ? 267 LEU B O   1 
ATOM   5365  C CB  . LEU B 1 267 ? -12.596 -19.875 -31.986 1.00 54.34  ? 267 LEU B CB  1 
ATOM   5366  C CG  . LEU B 1 267 ? -12.420 -20.334 -30.533 1.00 58.36  ? 267 LEU B CG  1 
ATOM   5367  C CD1 . LEU B 1 267 ? -13.699 -20.155 -29.761 1.00 61.93  ? 267 LEU B CD1 1 
ATOM   5368  C CD2 . LEU B 1 267 ? -11.953 -21.763 -30.445 1.00 59.89  ? 267 LEU B CD2 1 
ATOM   5369  N N   . GLY B 1 268 ? -12.980 -20.804 -34.852 1.00 62.81  ? 268 GLY B N   1 
ATOM   5370  C CA  . GLY B 1 268 ? -13.386 -20.871 -36.255 1.00 62.79  ? 268 GLY B CA  1 
ATOM   5371  C C   . GLY B 1 268 ? -13.757 -19.492 -36.824 1.00 60.88  ? 268 GLY B C   1 
ATOM   5372  O O   . GLY B 1 268 ? -13.425 -19.170 -37.948 1.00 57.62  ? 268 GLY B O   1 
ATOM   5373  N N   . ASP B 1 269 ? -14.458 -18.692 -36.046 1.00 62.98  ? 269 ASP B N   1 
ATOM   5374  C CA  . ASP B 1 269 ? -15.050 -17.480 -36.576 1.00 68.15  ? 269 ASP B CA  1 
ATOM   5375  C C   . ASP B 1 269 ? -14.036 -16.327 -36.542 1.00 68.18  ? 269 ASP B C   1 
ATOM   5376  O O   . ASP B 1 269 ? -14.316 -15.260 -37.048 1.00 76.41  ? 269 ASP B O   1 
ATOM   5377  C CB  . ASP B 1 269 ? -16.318 -17.119 -35.829 1.00 71.51  ? 269 ASP B CB  1 
ATOM   5378  C CG  . ASP B 1 269 ? -16.129 -16.874 -34.343 1.00 77.84  ? 269 ASP B CG  1 
ATOM   5379  O OD1 . ASP B 1 269 ? -15.206 -17.484 -33.769 1.00 84.33  ? 269 ASP B OD1 1 
ATOM   5380  O OD2 . ASP B 1 269 ? -16.866 -16.039 -33.787 1.00 81.86  ? 269 ASP B OD2 1 
ATOM   5381  N N   . ALA B 1 270 ? -12.849 -16.555 -35.970 1.00 70.08  ? 270 ALA B N   1 
ATOM   5382  C CA  . ALA B 1 270 ? -11.927 -15.455 -35.661 1.00 66.99  ? 270 ALA B CA  1 
ATOM   5383  C C   . ALA B 1 270 ? -11.537 -14.694 -36.932 1.00 70.32  ? 270 ALA B C   1 
ATOM   5384  O O   . ALA B 1 270 ? -11.506 -15.259 -38.031 1.00 70.12  ? 270 ALA B O   1 
ATOM   5385  C CB  . ALA B 1 270 ? -10.705 -15.980 -34.953 1.00 65.87  ? 270 ALA B CB  1 
ATOM   5386  N N   . ASP B 1 271 ? -11.226 -13.403 -36.749 1.00 72.28  ? 271 ASP B N   1 
ATOM   5387  C CA  . ASP B 1 271 ? -10.605 -12.584 -37.779 1.00 72.71  ? 271 ASP B CA  1 
ATOM   5388  C C   . ASP B 1 271 ? -9.154  -13.033 -37.983 1.00 67.16  ? 271 ASP B C   1 
ATOM   5389  O O   . ASP B 1 271 ? -8.293  -12.738 -37.157 1.00 73.20  ? 271 ASP B O   1 
ATOM   5390  C CB  . ASP B 1 271 ? -10.686 -11.107 -37.418 1.00 76.00  ? 271 ASP B CB  1 
ATOM   5391  C CG  . ASP B 1 271 ? -9.937  -10.168 -38.351 1.00 82.39  ? 271 ASP B CG  1 
ATOM   5392  O OD1 . ASP B 1 271 ? -9.714  -10.547 -39.519 1.00 97.43  ? 271 ASP B OD1 1 
ATOM   5393  O OD2 . ASP B 1 271 ? -9.570  -9.092  -37.905 1.00 88.99  ? 271 ASP B OD2 1 
ATOM   5394  N N   . LEU B 1 272 ? -8.894  -13.679 -39.130 1.00 63.24  ? 272 LEU B N   1 
ATOM   5395  C CA  . LEU B 1 272 ? -7.652  -14.401 -39.368 1.00 69.89  ? 272 LEU B CA  1 
ATOM   5396  C C   . LEU B 1 272 ? -6.461  -13.433 -39.393 1.00 73.39  ? 272 LEU B C   1 
ATOM   5397  O O   . LEU B 1 272 ? -5.435  -13.704 -38.788 1.00 71.75  ? 272 LEU B O   1 
ATOM   5398  C CB  . LEU B 1 272 ? -7.781  -15.177 -40.678 1.00 78.13  ? 272 LEU B CB  1 
ATOM   5399  C CG  . LEU B 1 272 ? -6.502  -15.833 -41.221 1.00 85.83  ? 272 LEU B CG  1 
ATOM   5400  C CD1 . LEU B 1 272 ? -6.284  -17.242 -40.668 1.00 85.62  ? 272 LEU B CD1 1 
ATOM   5401  C CD2 . LEU B 1 272 ? -6.532  -15.863 -42.748 1.00 89.49  ? 272 LEU B CD2 1 
ATOM   5402  N N   . GLU B 1 273 ? -6.606  -12.305 -40.098 1.00 82.57  ? 273 GLU B N   1 
ATOM   5403  C CA  . GLU B 1 273 ? -5.493  -11.372 -40.288 1.00 80.36  ? 273 GLU B CA  1 
ATOM   5404  C C   . GLU B 1 273 ? -5.034  -10.799 -38.928 1.00 72.30  ? 273 GLU B C   1 
ATOM   5405  O O   . GLU B 1 273 ? -3.835  -10.688 -38.672 1.00 62.68  ? 273 GLU B O   1 
ATOM   5406  C CB  . GLU B 1 273 ? -5.883  -10.267 -41.274 1.00 82.84  ? 273 GLU B CB  1 
ATOM   5407  C CG  . GLU B 1 273 ? -4.814  -9.998  -42.330 1.00 85.72  ? 273 GLU B CG  1 
ATOM   5408  C CD  . GLU B 1 273 ? -4.276  -11.257 -43.018 1.00 91.32  ? 273 GLU B CD  1 
ATOM   5409  O OE1 . GLU B 1 273 ? -3.035  -11.393 -43.081 1.00 80.67  ? 273 GLU B OE1 1 
ATOM   5410  O OE2 . GLU B 1 273 ? -5.093  -12.104 -43.485 1.00 84.37  ? 273 GLU B OE2 1 
ATOM   5411  N N   . GLN B 1 274 ? -5.996  -10.448 -38.062 1.00 67.22  ? 274 GLN B N   1 
ATOM   5412  C CA  . GLN B 1 274 ? -5.678  -9.882  -36.749 1.00 68.17  ? 274 GLN B CA  1 
ATOM   5413  C C   . GLN B 1 274 ? -4.978  -10.927 -35.865 1.00 63.51  ? 274 GLN B C   1 
ATOM   5414  O O   . GLN B 1 274 ? -4.039  -10.602 -35.148 1.00 58.46  ? 274 GLN B O   1 
ATOM   5415  C CB  . GLN B 1 274 ? -6.920  -9.343  -36.044 1.00 74.06  ? 274 GLN B CB  1 
ATOM   5416  C CG  . GLN B 1 274 ? -6.984  -7.821  -35.996 1.00 78.94  ? 274 GLN B CG  1 
ATOM   5417  C CD  . GLN B 1 274 ? -8.307  -7.295  -35.467 1.00 98.78  ? 274 GLN B CD  1 
ATOM   5418  O OE1 . GLN B 1 274 ? -9.032  -6.562  -36.155 1.00 96.79  ? 274 GLN B OE1 1 
ATOM   5419  N NE2 . GLN B 1 274 ? -8.639  -7.671  -34.233 1.00 103.93 ? 274 GLN B NE2 1 
ATOM   5420  N N   . ALA B 1 275 ? -5.447  -12.176 -35.918 1.00 59.12  ? 275 ALA B N   1 
ATOM   5421  C CA  . ALA B 1 275 ? -4.897  -13.236 -35.081 1.00 62.08  ? 275 ALA B CA  1 
ATOM   5422  C C   . ALA B 1 275 ? -3.426  -13.463 -35.422 1.00 69.46  ? 275 ALA B C   1 
ATOM   5423  O O   . ALA B 1 275 ? -2.592  -13.600 -34.533 1.00 66.68  ? 275 ALA B O   1 
ATOM   5424  C CB  . ALA B 1 275 ? -5.698  -14.509 -35.243 1.00 53.84  ? 275 ALA B CB  1 
ATOM   5425  N N   . VAL B 1 276 ? -3.120  -13.502 -36.716 1.00 73.64  ? 276 VAL B N   1 
ATOM   5426  C CA  . VAL B 1 276 ? -1.786  -13.844 -37.171 1.00 64.98  ? 276 VAL B CA  1 
ATOM   5427  C C   . VAL B 1 276 ? -0.824  -12.777 -36.678 1.00 57.74  ? 276 VAL B C   1 
ATOM   5428  O O   . VAL B 1 276 ? 0.200   -13.090 -36.090 1.00 62.61  ? 276 VAL B O   1 
ATOM   5429  C CB  . VAL B 1 276 ? -1.727  -14.002 -38.704 1.00 64.67  ? 276 VAL B CB  1 
ATOM   5430  C CG1 . VAL B 1 276 ? -0.297  -14.196 -39.210 1.00 65.20  ? 276 VAL B CG1 1 
ATOM   5431  C CG2 . VAL B 1 276 ? -2.616  -15.153 -39.180 1.00 68.84  ? 276 VAL B CG2 1 
ATOM   5432  N N   . SER B 1 277 ? -1.183  -11.516 -36.886 1.00 56.25  ? 277 SER B N   1 
ATOM   5433  C CA  . SER B 1 277 ? -0.314  -10.422 -36.509 1.00 60.30  ? 277 SER B CA  1 
ATOM   5434  C C   . SER B 1 277 ? -0.101  -10.433 -34.982 1.00 64.83  ? 277 SER B C   1 
ATOM   5435  O O   . SER B 1 277 ? 1.023   -10.269 -34.503 1.00 65.97  ? 277 SER B O   1 
ATOM   5436  C CB  . SER B 1 277 ? -0.851  -9.115  -36.986 1.00 57.43  ? 277 SER B CB  1 
ATOM   5437  O OG  . SER B 1 277 ? -1.609  -8.492  -35.971 1.00 66.59  ? 277 SER B OG  1 
ATOM   5438  N N   . ALA B 1 278 ? -1.187  -10.675 -34.237 1.00 62.14  ? 278 ALA B N   1 
ATOM   5439  C CA  . ALA B 1 278 ? -1.131  -10.737 -32.784 1.00 59.79  ? 278 ALA B CA  1 
ATOM   5440  C C   . ALA B 1 278 ? -0.202  -11.869 -32.334 1.00 59.50  ? 278 ALA B C   1 
ATOM   5441  O O   . ALA B 1 278 ? 0.582   -11.691 -31.404 1.00 58.61  ? 278 ALA B O   1 
ATOM   5442  C CB  . ALA B 1 278 ? -2.532  -10.914 -32.210 1.00 59.86  ? 278 ALA B CB  1 
ATOM   5443  N N   . ALA B 1 279 ? -0.315  -13.033 -32.990 1.00 51.57  ? 279 ALA B N   1 
ATOM   5444  C CA  . ALA B 1 279 ? 0.490   -14.193 -32.644 1.00 51.25  ? 279 ALA B CA  1 
ATOM   5445  C C   . ALA B 1 279 ? 1.954   -13.919 -32.958 1.00 54.41  ? 279 ALA B C   1 
ATOM   5446  O O   . ALA B 1 279 ? 2.813   -14.267 -32.183 1.00 59.83  ? 279 ALA B O   1 
ATOM   5447  C CB  . ALA B 1 279 ? -0.001  -15.416 -33.374 1.00 50.10  ? 279 ALA B CB  1 
ATOM   5448  N N   . VAL B 1 280 ? 2.218   -13.278 -34.099 1.00 59.26  ? 280 VAL B N   1 
ATOM   5449  C CA  . VAL B 1 280 ? 3.583   -12.969 -34.506 1.00 61.77  ? 280 VAL B CA  1 
ATOM   5450  C C   . VAL B 1 280 ? 4.188   -11.972 -33.522 1.00 63.27  ? 280 VAL B C   1 
ATOM   5451  O O   . VAL B 1 280 ? 5.296   -12.169 -33.045 1.00 73.17  ? 280 VAL B O   1 
ATOM   5452  C CB  . VAL B 1 280 ? 3.658   -12.445 -35.957 1.00 58.12  ? 280 VAL B CB  1 
ATOM   5453  C CG1 . VAL B 1 280 ? 4.977   -11.740 -36.247 1.00 51.90  ? 280 VAL B CG1 1 
ATOM   5454  C CG2 . VAL B 1 280 ? 3.425   -13.565 -36.959 1.00 59.02  ? 280 VAL B CG2 1 
ATOM   5455  N N   . PHE B 1 281 ? 3.467   -10.895 -33.240 1.00 68.54  ? 281 PHE B N   1 
ATOM   5456  C CA  . PHE B 1 281 ? 3.975   -9.874  -32.341 1.00 74.80  ? 281 PHE B CA  1 
ATOM   5457  C C   . PHE B 1 281 ? 4.137   -10.479 -30.939 1.00 74.91  ? 281 PHE B C   1 
ATOM   5458  O O   . PHE B 1 281 ? 5.077   -10.154 -30.227 1.00 77.99  ? 281 PHE B O   1 
ATOM   5459  C CB  . PHE B 1 281 ? 3.064   -8.651  -32.346 1.00 77.28  ? 281 PHE B CB  1 
ATOM   5460  C CG  . PHE B 1 281 ? 3.589   -7.489  -31.510 1.00 98.63  ? 281 PHE B CG  1 
ATOM   5461  C CD1 . PHE B 1 281 ? 2.896   -7.047  -30.380 1.00 113.47 ? 281 PHE B CD1 1 
ATOM   5462  C CD2 . PHE B 1 281 ? 4.799   -6.858  -31.827 1.00 104.14 ? 281 PHE B CD2 1 
ATOM   5463  C CE1 . PHE B 1 281 ? 3.378   -5.979  -29.614 1.00 109.10 ? 281 PHE B CE1 1 
ATOM   5464  C CE2 . PHE B 1 281 ? 5.281   -5.794  -31.048 1.00 104.62 ? 281 PHE B CE2 1 
ATOM   5465  C CZ  . PHE B 1 281 ? 4.574   -5.363  -29.947 1.00 100.89 ? 281 PHE B CZ  1 
ATOM   5466  N N   . GLY B 1 282 ? 3.223   -11.377 -30.575 1.00 70.24  ? 282 GLY B N   1 
ATOM   5467  C CA  . GLY B 1 282 ? 3.244   -12.038 -29.277 1.00 69.61  ? 282 GLY B CA  1 
ATOM   5468  C C   . GLY B 1 282 ? 4.535   -12.822 -29.051 1.00 72.31  ? 282 GLY B C   1 
ATOM   5469  O O   . GLY B 1 282 ? 5.297   -12.514 -28.141 1.00 82.27  ? 282 GLY B O   1 
ATOM   5470  N N   . LYS B 1 283 ? 4.765   -13.847 -29.879 1.00 68.75  ? 283 LYS B N   1 
ATOM   5471  C CA  . LYS B 1 283 ? 5.878   -14.760 -29.673 1.00 61.37  ? 283 LYS B CA  1 
ATOM   5472  C C   . LYS B 1 283 ? 7.209   -14.085 -30.021 1.00 59.73  ? 283 LYS B C   1 
ATOM   5473  O O   . LYS B 1 283 ? 8.151   -14.173 -29.258 1.00 59.82  ? 283 LYS B O   1 
ATOM   5474  C CB  . LYS B 1 283 ? 5.741   -16.037 -30.493 1.00 59.07  ? 283 LYS B CB  1 
ATOM   5475  C CG  . LYS B 1 283 ? 6.924   -16.975 -30.339 1.00 59.28  ? 283 LYS B CG  1 
ATOM   5476  C CD  . LYS B 1 283 ? 6.586   -18.255 -29.600 1.00 59.87  ? 283 LYS B CD  1 
ATOM   5477  C CE  . LYS B 1 283 ? 7.778   -18.948 -29.031 1.00 61.58  ? 283 LYS B CE  1 
ATOM   5478  N NZ  . LYS B 1 283 ? 8.183   -18.361 -27.768 1.00 61.02  ? 283 LYS B NZ  1 
ATOM   5479  N N   . PHE B 1 284 ? 7.280   -13.435 -31.192 1.00 60.81  ? 284 PHE B N   1 
ATOM   5480  C CA  . PHE B 1 284 ? 8.563   -13.055 -31.776 1.00 58.31  ? 284 PHE B CA  1 
ATOM   5481  C C   . PHE B 1 284 ? 8.890   -11.596 -31.481 1.00 68.82  ? 284 PHE B C   1 
ATOM   5482  O O   . PHE B 1 284 ? 9.695   -10.996 -32.179 1.00 88.09  ? 284 PHE B O   1 
ATOM   5483  C CB  . PHE B 1 284 ? 8.571   -13.298 -33.284 1.00 51.02  ? 284 PHE B CB  1 
ATOM   5484  C CG  . PHE B 1 284 ? 8.514   -14.759 -33.639 1.00 52.04  ? 284 PHE B CG  1 
ATOM   5485  C CD1 . PHE B 1 284 ? 9.591   -15.591 -33.376 1.00 52.34  ? 284 PHE B CD1 1 
ATOM   5486  C CD2 . PHE B 1 284 ? 7.380   -15.310 -34.202 1.00 54.19  ? 284 PHE B CD2 1 
ATOM   5487  C CE1 . PHE B 1 284 ? 9.528   -16.938 -33.665 1.00 53.08  ? 284 PHE B CE1 1 
ATOM   5488  C CE2 . PHE B 1 284 ? 7.321   -16.668 -34.484 1.00 59.84  ? 284 PHE B CE2 1 
ATOM   5489  C CZ  . PHE B 1 284 ? 8.392   -17.474 -34.221 1.00 52.75  ? 284 PHE B CZ  1 
ATOM   5490  N N   . ILE B 1 290 ? 9.694   -14.119 -23.522 1.00 203.24 ? 290 ILE B N   1 
ATOM   5491  C CA  . ILE B 1 290 ? 8.752   -13.200 -22.875 1.00 172.23 ? 290 ILE B CA  1 
ATOM   5492  C C   . ILE B 1 290 ? 7.959   -13.958 -21.804 1.00 180.12 ? 290 ILE B C   1 
ATOM   5493  O O   . ILE B 1 290 ? 7.711   -15.152 -21.952 1.00 195.07 ? 290 ILE B O   1 
ATOM   5494  C CB  . ILE B 1 290 ? 7.821   -12.571 -23.930 1.00 137.89 ? 290 ILE B CB  1 
ATOM   5495  C CG1 . ILE B 1 290 ? 8.603   -12.064 -25.136 1.00 122.37 ? 290 ILE B CG1 1 
ATOM   5496  C CG2 . ILE B 1 290 ? 6.952   -11.471 -23.324 1.00 130.32 ? 290 ILE B CG2 1 
ATOM   5497  C CD1 . ILE B 1 290 ? 7.806   -12.043 -26.411 1.00 117.16 ? 290 ILE B CD1 1 
ATOM   5498  N N   . CYS B 1 291 ? 7.570   -13.248 -20.720 1.00 169.92 ? 291 CYS B N   1 
ATOM   5499  C CA  . CYS B 1 291 ? 6.756   -13.843 -19.656 1.00 163.18 ? 291 CYS B CA  1 
ATOM   5500  C C   . CYS B 1 291 ? 5.274   -13.455 -19.821 1.00 181.89 ? 291 CYS B C   1 
ATOM   5501  O O   . CYS B 1 291 ? 4.427   -13.879 -19.026 1.00 178.91 ? 291 CYS B O   1 
ATOM   5502  C CB  . CYS B 1 291 ? 7.281   -13.476 -18.269 1.00 144.42 ? 291 CYS B CB  1 
ATOM   5503  S SG  . CYS B 1 291 ? 7.603   -11.710 -18.055 1.00 136.55 ? 291 CYS B SG  1 
ATOM   5504  N N   . MET B 1 292 ? 4.967   -12.649 -20.855 1.00 185.17 ? 292 MET B N   1 
ATOM   5505  C CA  . MET B 1 292 ? 3.615   -12.595 -21.412 1.00 177.32 ? 292 MET B CA  1 
ATOM   5506  C C   . MET B 1 292 ? 3.507   -13.628 -22.544 1.00 150.54 ? 292 MET B C   1 
ATOM   5507  O O   . MET B 1 292 ? 2.978   -13.342 -23.619 1.00 115.10 ? 292 MET B O   1 
ATOM   5508  C CB  . MET B 1 292 ? 3.275   -11.184 -21.919 1.00 176.96 ? 292 MET B CB  1 
ATOM   5509  C CG  . MET B 1 292 ? 1.793   -10.987 -22.280 1.00 174.07 ? 292 MET B CG  1 
ATOM   5510  S SD  . MET B 1 292 ? 0.719   -10.721 -20.852 1.00 157.39 ? 292 MET B SD  1 
ATOM   5511  C CE  . MET B 1 292 ? 0.640   -8.923  -20.822 1.00 138.12 ? 292 MET B CE  1 
ATOM   5512  N N   . ALA B 1 293 ? 3.929   -14.859 -22.239 1.00 133.22 ? 293 ALA B N   1 
ATOM   5513  C CA  . ALA B 1 293 ? 4.416   -15.786 -23.240 1.00 121.77 ? 293 ALA B CA  1 
ATOM   5514  C C   . ALA B 1 293 ? 3.268   -16.302 -24.099 1.00 112.87 ? 293 ALA B C   1 
ATOM   5515  O O   . ALA B 1 293 ? 2.111   -16.349 -23.659 1.00 99.99  ? 293 ALA B O   1 
ATOM   5516  C CB  . ALA B 1 293 ? 5.149   -16.923 -22.572 1.00 120.47 ? 293 ALA B CB  1 
ATOM   5517  N N   . ILE B 1 294 ? 3.618   -16.648 -25.344 1.00 97.06  ? 294 ILE B N   1 
ATOM   5518  C CA  . ILE B 1 294 ? 2.815   -17.495 -26.203 1.00 81.65  ? 294 ILE B CA  1 
ATOM   5519  C C   . ILE B 1 294 ? 3.698   -18.651 -26.651 1.00 68.14  ? 294 ILE B C   1 
ATOM   5520  O O   . ILE B 1 294 ? 4.697   -18.427 -27.314 1.00 76.67  ? 294 ILE B O   1 
ATOM   5521  C CB  . ILE B 1 294 ? 2.285   -16.692 -27.409 1.00 87.51  ? 294 ILE B CB  1 
ATOM   5522  C CG1 . ILE B 1 294 ? 1.476   -15.458 -26.972 1.00 97.88  ? 294 ILE B CG1 1 
ATOM   5523  C CG2 . ILE B 1 294 ? 1.491   -17.582 -28.356 1.00 86.31  ? 294 ILE B CG2 1 
ATOM   5524  C CD1 . ILE B 1 294 ? 0.158   -15.775 -26.270 1.00 102.38 ? 294 ILE B CD1 1 
ATOM   5525  N N   . ASN B 1 295 ? 3.328   -19.880 -26.278 1.00 63.39  ? 295 ASN B N   1 
ATOM   5526  C CA  . ASN B 1 295 ? 4.189   -21.048 -26.505 1.00 65.97  ? 295 ASN B CA  1 
ATOM   5527  C C   . ASN B 1 295 ? 3.478   -22.077 -27.397 1.00 64.39  ? 295 ASN B C   1 
ATOM   5528  O O   . ASN B 1 295 ? 4.126   -22.878 -28.072 1.00 71.65  ? 295 ASN B O   1 
ATOM   5529  C CB  . ASN B 1 295 ? 4.617   -21.667 -25.181 1.00 77.74  ? 295 ASN B CB  1 
ATOM   5530  C CG  . ASN B 1 295 ? 4.871   -20.613 -24.116 1.00 87.32  ? 295 ASN B CG  1 
ATOM   5531  O OD1 . ASN B 1 295 ? 4.039   -20.425 -23.219 1.00 100.02 ? 295 ASN B OD1 1 
ATOM   5532  N ND2 . ASN B 1 295 ? 5.973   -19.876 -24.229 1.00 72.28  ? 295 ASN B ND2 1 
ATOM   5533  N N   . ARG B 1 296 ? 2.074   -22.002 -27.377 1.00 61.79  ? 296 ARG B N   1 
ATOM   5534  C CA  . ARG B 1 296 ? 1.245   -22.892 -28.174 1.00 54.38  ? 296 ARG B CA  1 
ATOM   5535  C C   . ARG B 1 296 ? 0.204   -22.062 -28.917 1.00 54.99  ? 296 ARG B C   1 
ATOM   5536  O O   . ARG B 1 296 ? -0.430  -21.166 -28.326 1.00 50.68  ? 296 ARG B O   1 
ATOM   5537  C CB  . ARG B 1 296 ? 0.570   -23.949 -27.297 1.00 50.00  ? 296 ARG B CB  1 
ATOM   5538  C CG  . ARG B 1 296 ? 1.531   -24.959 -26.693 1.00 50.00  ? 296 ARG B CG  1 
ATOM   5539  C CD  . ARG B 1 296 ? 0.856   -26.038 -25.860 1.00 50.00  ? 296 ARG B CD  1 
ATOM   5540  N NE  . ARG B 1 296 ? -0.142  -25.483 -24.950 1.00 50.00  ? 296 ARG B NE  1 
ATOM   5541  C CZ  . ARG B 1 296 ? -0.952  -26.214 -24.198 1.00 50.00  ? 296 ARG B CZ  1 
ATOM   5542  N NH1 . ARG B 1 296 ? -0.885  -27.538 -24.240 1.00 50.00  ? 296 ARG B NH1 1 
ATOM   5543  N NH2 . ARG B 1 296 ? -1.831  -25.624 -23.398 1.00 50.00  ? 296 ARG B NH2 1 
ATOM   5544  N N   . ILE B 1 297 ? 0.108   -22.437 -30.177 1.00 50.05  ? 297 ILE B N   1 
ATOM   5545  C CA  . ILE B 1 297 ? -0.951  -21.853 -30.979 1.00 52.00  ? 297 ILE B CA  1 
ATOM   5546  C C   . ILE B 1 297 ? -1.910  -22.967 -31.400 1.00 52.88  ? 297 ILE B C   1 
ATOM   5547  O O   . ILE B 1 297 ? -1.508  -23.928 -32.047 1.00 58.92  ? 297 ILE B O   1 
ATOM   5548  C CB  . ILE B 1 297 ? -0.361  -21.104 -32.186 1.00 50.43  ? 297 ILE B CB  1 
ATOM   5549  C CG1 . ILE B 1 297 ? 0.660   -20.058 -31.730 1.00 48.04  ? 297 ILE B CG1 1 
ATOM   5550  C CG2 . ILE B 1 297 ? -1.470  -20.493 -33.060 1.00 48.57  ? 297 ILE B CG2 1 
ATOM   5551  C CD1 . ILE B 1 297 ? 1.101   -19.083 -32.815 1.00 50.07  ? 297 ILE B CD1 1 
ATOM   5552  N N   . ILE B 1 298 ? -3.171  -22.824 -31.004 1.00 50.76  ? 298 ILE B N   1 
ATOM   5553  C CA  . ILE B 1 298 ? -4.201  -23.814 -31.283 1.00 52.56  ? 298 ILE B CA  1 
ATOM   5554  C C   . ILE B 1 298 ? -5.248  -23.166 -32.191 1.00 52.15  ? 298 ILE B C   1 
ATOM   5555  O O   . ILE B 1 298 ? -5.832  -22.127 -31.837 1.00 53.40  ? 298 ILE B O   1 
ATOM   5556  C CB  . ILE B 1 298 ? -4.825  -24.342 -29.966 1.00 48.65  ? 298 ILE B CB  1 
ATOM   5557  C CG1 . ILE B 1 298 ? -3.750  -24.760 -28.966 1.00 54.61  ? 298 ILE B CG1 1 
ATOM   5558  C CG2 . ILE B 1 298 ? -5.815  -25.483 -30.235 1.00 53.04  ? 298 ILE B CG2 1 
ATOM   5559  C CD1 . ILE B 1 298 ? -4.287  -25.154 -27.587 1.00 53.57  ? 298 ILE B CD1 1 
ATOM   5560  N N   . VAL B 1 299 ? -5.465  -23.765 -33.369 1.00 51.47  ? 299 VAL B N   1 
ATOM   5561  C CA  . VAL B 1 299 ? -6.408  -23.215 -34.345 1.00 61.12  ? 299 VAL B CA  1 
ATOM   5562  C C   . VAL B 1 299 ? -7.458  -24.275 -34.691 1.00 60.19  ? 299 VAL B C   1 
ATOM   5563  O O   . VAL B 1 299 ? -7.127  -25.435 -34.919 1.00 66.69  ? 299 VAL B O   1 
ATOM   5564  C CB  . VAL B 1 299 ? -5.683  -22.708 -35.610 1.00 62.54  ? 299 VAL B CB  1 
ATOM   5565  C CG1 . VAL B 1 299 ? -6.642  -22.013 -36.567 1.00 69.04  ? 299 VAL B CG1 1 
ATOM   5566  C CG2 . VAL B 1 299 ? -4.522  -21.771 -35.266 1.00 66.39  ? 299 VAL B CG2 1 
ATOM   5567  N N   . GLU B 1 300 ? -8.726  -23.857 -34.744 1.00 57.82  ? 300 GLU B N   1 
ATOM   5568  C CA  . GLU B 1 300 ? -9.799  -24.739 -35.182 1.00 63.46  ? 300 GLU B CA  1 
ATOM   5569  C C   . GLU B 1 300 ? -9.519  -25.179 -36.627 1.00 62.65  ? 300 GLU B C   1 
ATOM   5570  O O   . GLU B 1 300 ? -8.954  -24.421 -37.421 1.00 66.99  ? 300 GLU B O   1 
ATOM   5571  C CB  . GLU B 1 300 ? -11.171 -24.064 -35.035 1.00 64.93  ? 300 GLU B CB  1 
ATOM   5572  C CG  . GLU B 1 300 ? -12.283 -25.036 -34.639 1.00 67.24  ? 300 GLU B CG  1 
ATOM   5573  C CD  . GLU B 1 300 ? -13.623 -24.407 -34.308 1.00 67.40  ? 300 GLU B CD  1 
ATOM   5574  O OE1 . GLU B 1 300 ? -14.567 -25.181 -34.050 1.00 76.43  ? 300 GLU B OE1 1 
ATOM   5575  O OE2 . GLU B 1 300 ? -13.719 -23.169 -34.259 1.00 66.71  ? 300 GLU B OE2 1 
ATOM   5576  N N   . ASP B 1 301 ? -9.968  -26.398 -36.960 1.00 67.67  ? 301 ASP B N   1 
ATOM   5577  C CA  . ASP B 1 301 ? -9.517  -27.118 -38.148 1.00 69.02  ? 301 ASP B CA  1 
ATOM   5578  C C   . ASP B 1 301 ? -9.776  -26.310 -39.433 1.00 70.45  ? 301 ASP B C   1 
ATOM   5579  O O   . ASP B 1 301 ? -8.989  -26.380 -40.375 1.00 63.35  ? 301 ASP B O   1 
ATOM   5580  C CB  . ASP B 1 301 ? -10.176 -28.476 -38.246 1.00 72.21  ? 301 ASP B CB  1 
ATOM   5581  C CG  . ASP B 1 301 ? -9.896  -29.219 -39.537 1.00 76.93  ? 301 ASP B CG  1 
ATOM   5582  O OD1 . ASP B 1 301 ? -8.744  -29.662 -39.714 1.00 70.75  ? 301 ASP B OD1 1 
ATOM   5583  O OD2 . ASP B 1 301 ? -10.817 -29.290 -40.383 1.00 79.37  ? 301 ASP B OD2 1 
ATOM   5584  N N   . SER B 1 302 ? -10.898 -25.577 -39.480 1.00 73.45  ? 302 SER B N   1 
ATOM   5585  C CA  . SER B 1 302 ? -11.280 -24.860 -40.689 1.00 69.30  ? 302 SER B CA  1 
ATOM   5586  C C   . SER B 1 302 ? -10.209 -23.820 -41.063 1.00 70.44  ? 302 SER B C   1 
ATOM   5587  O O   . SER B 1 302 ? -9.833  -23.723 -42.221 1.00 78.68  ? 302 SER B O   1 
ATOM   5588  C CB  . SER B 1 302 ? -12.661 -24.236 -40.563 1.00 67.74  ? 302 SER B CB  1 
ATOM   5589  O OG  . SER B 1 302 ? -12.759 -23.386 -39.435 1.00 73.22  ? 302 SER B OG  1 
ATOM   5590  N N   . LEU B 1 303 ? -9.683  -23.079 -40.069 1.00 72.13  ? 303 LEU B N   1 
ATOM   5591  C CA  . LEU B 1 303 ? -8.744  -21.983 -40.352 1.00 69.46  ? 303 LEU B CA  1 
ATOM   5592  C C   . LEU B 1 303 ? -7.292  -22.467 -40.342 1.00 61.91  ? 303 LEU B C   1 
ATOM   5593  O O   . LEU B 1 303 ? -6.407  -21.690 -40.675 1.00 56.92  ? 303 LEU B O   1 
ATOM   5594  C CB  . LEU B 1 303 ? -8.896  -20.839 -39.362 1.00 77.47  ? 303 LEU B CB  1 
ATOM   5595  C CG  . LEU B 1 303 ? -10.084 -19.923 -39.575 1.00 86.40  ? 303 LEU B CG  1 
ATOM   5596  C CD1 . LEU B 1 303 ? -11.326 -20.607 -39.048 1.00 93.31  ? 303 LEU B CD1 1 
ATOM   5597  C CD2 . LEU B 1 303 ? -9.842  -18.564 -38.899 1.00 85.53  ? 303 LEU B CD2 1 
ATOM   5598  N N   . TYR B 1 304 ? -7.040  -23.704 -39.861 1.00 57.83  ? 304 TYR B N   1 
ATOM   5599  C CA  . TYR B 1 304 ? -5.685  -24.115 -39.489 1.00 57.90  ? 304 TYR B CA  1 
ATOM   5600  C C   . TYR B 1 304 ? -4.730  -23.807 -40.642 1.00 63.10  ? 304 TYR B C   1 
ATOM   5601  O O   . TYR B 1 304 ? -3.717  -23.118 -40.454 1.00 63.97  ? 304 TYR B O   1 
ATOM   5602  C CB  . TYR B 1 304 ? -5.617  -25.596 -39.083 1.00 58.40  ? 304 TYR B CB  1 
ATOM   5603  C CG  . TYR B 1 304 ? -4.207  -26.073 -38.794 1.00 59.99  ? 304 TYR B CG  1 
ATOM   5604  C CD1 . TYR B 1 304 ? -3.361  -26.449 -39.832 1.00 67.52  ? 304 TYR B CD1 1 
ATOM   5605  C CD2 . TYR B 1 304 ? -3.680  -26.047 -37.493 1.00 65.68  ? 304 TYR B CD2 1 
ATOM   5606  C CE1 . TYR B 1 304 ? -2.047  -26.839 -39.594 1.00 75.01  ? 304 TYR B CE1 1 
ATOM   5607  C CE2 . TYR B 1 304 ? -2.360  -26.414 -37.241 1.00 69.35  ? 304 TYR B CE2 1 
ATOM   5608  C CZ  . TYR B 1 304 ? -1.538  -26.808 -38.299 1.00 70.66  ? 304 TYR B CZ  1 
ATOM   5609  O OH  . TYR B 1 304 ? -0.249  -27.189 -38.082 1.00 64.53  ? 304 TYR B OH  1 
ATOM   5610  N N   . ASP B 1 305 ? -5.064  -24.334 -41.831 1.00 67.73  ? 305 ASP B N   1 
ATOM   5611  C CA  . ASP B 1 305 ? -4.182  -24.277 -42.993 1.00 66.88  ? 305 ASP B CA  1 
ATOM   5612  C C   . ASP B 1 305 ? -3.983  -22.826 -43.416 1.00 62.99  ? 305 ASP B C   1 
ATOM   5613  O O   . ASP B 1 305 ? -2.865  -22.419 -43.731 1.00 69.37  ? 305 ASP B O   1 
ATOM   5614  C CB  . ASP B 1 305 ? -4.722  -25.134 -44.113 1.00 65.37  ? 305 ASP B CB  1 
ATOM   5615  C CG  . ASP B 1 305 ? -5.356  -26.426 -43.644 1.00 71.76  ? 305 ASP B CG  1 
ATOM   5616  O OD1 . ASP B 1 305 ? -6.515  -26.374 -43.173 1.00 82.44  ? 305 ASP B OD1 1 
ATOM   5617  O OD2 . ASP B 1 305 ? -4.663  -27.439 -43.653 1.00 68.04  ? 305 ASP B OD2 1 
ATOM   5618  N N   . ALA B 1 306 ? -5.062  -22.039 -43.379 1.00 54.29  ? 306 ALA B N   1 
ATOM   5619  C CA  . ALA B 1 306 ? -4.979  -20.634 -43.757 1.00 62.57  ? 306 ALA B CA  1 
ATOM   5620  C C   . ALA B 1 306 ? -4.112  -19.875 -42.740 1.00 75.58  ? 306 ALA B C   1 
ATOM   5621  O O   . ALA B 1 306 ? -3.252  -19.084 -43.134 1.00 79.23  ? 306 ALA B O   1 
ATOM   5622  C CB  . ALA B 1 306 ? -6.375  -20.031 -43.877 1.00 59.50  ? 306 ALA B CB  1 
ATOM   5623  N N   . PHE B 1 307 ? -4.333  -20.146 -41.430 1.00 72.93  ? 307 PHE B N   1 
ATOM   5624  C CA  . PHE B 1 307 ? -3.578  -19.486 -40.369 1.00 73.50  ? 307 PHE B CA  1 
ATOM   5625  C C   . PHE B 1 307 ? -2.098  -19.857 -40.505 1.00 68.27  ? 307 PHE B C   1 
ATOM   5626  O O   . PHE B 1 307 ? -1.228  -18.981 -40.474 1.00 65.24  ? 307 PHE B O   1 
ATOM   5627  C CB  . PHE B 1 307 ? -4.101  -19.836 -38.962 1.00 71.62  ? 307 PHE B CB  1 
ATOM   5628  C CG  . PHE B 1 307 ? -3.352  -19.131 -37.832 1.00 63.63  ? 307 PHE B CG  1 
ATOM   5629  C CD1 . PHE B 1 307 ? -2.164  -19.655 -37.323 1.00 60.30  ? 307 PHE B CD1 1 
ATOM   5630  C CD2 . PHE B 1 307 ? -3.806  -17.920 -37.317 1.00 68.40  ? 307 PHE B CD2 1 
ATOM   5631  C CE1 . PHE B 1 307 ? -1.467  -18.995 -36.323 1.00 59.65  ? 307 PHE B CE1 1 
ATOM   5632  C CE2 . PHE B 1 307 ? -3.097  -17.258 -36.318 1.00 66.74  ? 307 PHE B CE2 1 
ATOM   5633  C CZ  . PHE B 1 307 ? -1.935  -17.808 -35.817 1.00 63.40  ? 307 PHE B CZ  1 
ATOM   5634  N N   . ALA B 1 308 ? -1.826  -21.163 -40.647 1.00 62.16  ? 308 ALA B N   1 
ATOM   5635  C CA  . ALA B 1 308 ? -0.459  -21.664 -40.704 1.00 62.58  ? 308 ALA B CA  1 
ATOM   5636  C C   . ALA B 1 308 ? 0.296   -21.003 -41.861 1.00 70.16  ? 308 ALA B C   1 
ATOM   5637  O O   . ALA B 1 308 ? 1.449   -20.598 -41.707 1.00 72.84  ? 308 ALA B O   1 
ATOM   5638  C CB  . ALA B 1 308 ? -0.464  -23.183 -40.826 1.00 59.04  ? 308 ALA B CB  1 
ATOM   5639  N N   . ALA B 1 309 ? -0.378  -20.873 -43.008 1.00 75.43  ? 309 ALA B N   1 
ATOM   5640  C CA  . ALA B 1 309 ? 0.246   -20.332 -44.206 1.00 78.67  ? 309 ALA B CA  1 
ATOM   5641  C C   . ALA B 1 309 ? 0.670   -18.886 -43.965 1.00 64.32  ? 309 ALA B C   1 
ATOM   5642  O O   . ALA B 1 309 ? 1.830   -18.542 -44.171 1.00 63.09  ? 309 ALA B O   1 
ATOM   5643  C CB  . ALA B 1 309 ? -0.704  -20.445 -45.379 1.00 84.83  ? 309 ALA B CB  1 
ATOM   5644  N N   . ARG B 1 310 ? -0.285  -18.052 -43.525 1.00 69.32  ? 310 ARG B N   1 
ATOM   5645  C CA  . ARG B 1 310 ? -0.046  -16.622 -43.313 1.00 80.15  ? 310 ARG B CA  1 
ATOM   5646  C C   . ARG B 1 310 ? 1.027   -16.421 -42.238 1.00 82.31  ? 310 ARG B C   1 
ATOM   5647  O O   . ARG B 1 310 ? 1.936   -15.600 -42.402 1.00 75.34  ? 310 ARG B O   1 
ATOM   5648  C CB  . ARG B 1 310 ? -1.338  -15.914 -42.887 1.00 82.52  ? 310 ARG B CB  1 
ATOM   5649  C CG  . ARG B 1 310 ? -2.278  -15.572 -44.031 1.00 94.24  ? 310 ARG B CG  1 
ATOM   5650  C CD  . ARG B 1 310 ? -2.090  -14.147 -44.522 1.00 93.82  ? 310 ARG B CD  1 
ATOM   5651  N NE  . ARG B 1 310 ? -0.686  -13.837 -44.818 1.00 87.18  ? 310 ARG B NE  1 
ATOM   5652  C CZ  . ARG B 1 310 ? -0.060  -12.693 -44.499 1.00 89.69  ? 310 ARG B CZ  1 
ATOM   5653  N NH1 . ARG B 1 310 ? -0.702  -11.719 -43.858 1.00 88.01  ? 310 ARG B NH1 1 
ATOM   5654  N NH2 . ARG B 1 310 ? 1.205   -12.522 -44.837 1.00 92.11  ? 310 ARG B NH2 1 
ATOM   5655  N N   . PHE B 1 311 ? 0.902   -17.183 -41.136 1.00 75.34  ? 311 PHE B N   1 
ATOM   5656  C CA  . PHE B 1 311 ? 1.797   -17.067 -39.991 1.00 71.88  ? 311 PHE B CA  1 
ATOM   5657  C C   . PHE B 1 311 ? 3.240   -17.321 -40.419 1.00 70.53  ? 311 PHE B C   1 
ATOM   5658  O O   . PHE B 1 311 ? 4.120   -16.496 -40.173 1.00 66.98  ? 311 PHE B O   1 
ATOM   5659  C CB  . PHE B 1 311 ? 1.378   -18.055 -38.906 1.00 69.66  ? 311 PHE B CB  1 
ATOM   5660  C CG  . PHE B 1 311 ? 2.241   -18.033 -37.659 1.00 61.60  ? 311 PHE B CG  1 
ATOM   5661  C CD1 . PHE B 1 311 ? 2.238   -16.936 -36.814 1.00 63.02  ? 311 PHE B CD1 1 
ATOM   5662  C CD2 . PHE B 1 311 ? 3.008   -19.133 -37.305 1.00 63.52  ? 311 PHE B CD2 1 
ATOM   5663  C CE1 . PHE B 1 311 ? 2.992   -16.936 -35.655 1.00 65.75  ? 311 PHE B CE1 1 
ATOM   5664  C CE2 . PHE B 1 311 ? 3.758   -19.128 -36.137 1.00 65.07  ? 311 PHE B CE2 1 
ATOM   5665  C CZ  . PHE B 1 311 ? 3.750   -18.033 -35.320 1.00 61.70  ? 311 PHE B CZ  1 
ATOM   5666  N N   . VAL B 1 312 ? 3.473   -18.477 -41.044 1.00 66.54  ? 312 VAL B N   1 
ATOM   5667  C CA  . VAL B 1 312 ? 4.799   -18.844 -41.495 1.00 63.60  ? 312 VAL B CA  1 
ATOM   5668  C C   . VAL B 1 312 ? 5.362   -17.730 -42.377 1.00 69.89  ? 312 VAL B C   1 
ATOM   5669  O O   . VAL B 1 312 ? 6.560   -17.578 -42.505 1.00 68.12  ? 312 VAL B O   1 
ATOM   5670  C CB  . VAL B 1 312 ? 4.797   -20.192 -42.238 1.00 60.08  ? 312 VAL B CB  1 
ATOM   5671  C CG1 . VAL B 1 312 ? 6.054   -20.384 -43.081 1.00 58.77  ? 312 VAL B CG1 1 
ATOM   5672  C CG2 . VAL B 1 312 ? 4.613   -21.364 -41.285 1.00 57.90  ? 312 VAL B CG2 1 
ATOM   5673  N N   . GLU B 1 313 ? 4.526   -16.973 -43.013 1.00 73.95  ? 313 GLU B N   1 
ATOM   5674  C CA  . GLU B 1 313 ? 5.078   -16.169 -44.047 1.00 86.28  ? 313 GLU B CA  1 
ATOM   5675  C C   . GLU B 1 313 ? 5.556   -14.852 -43.511 1.00 79.33  ? 313 GLU B C   1 
ATOM   5676  O O   . GLU B 1 313 ? 6.617   -14.411 -43.895 1.00 78.20  ? 313 GLU B O   1 
ATOM   5677  C CB  . GLU B 1 313 ? 4.220   -16.123 -45.260 1.00 103.29 ? 313 GLU B CB  1 
ATOM   5678  C CG  . GLU B 1 313 ? 4.784   -17.099 -46.263 1.00 116.56 ? 313 GLU B CG  1 
ATOM   5679  C CD  . GLU B 1 313 ? 4.563   -16.734 -47.709 1.00 119.62 ? 313 GLU B CD  1 
ATOM   5680  O OE1 . GLU B 1 313 ? 3.603   -15.975 -48.009 1.00 121.91 ? 313 GLU B OE1 1 
ATOM   5681  O OE2 . GLU B 1 313 ? 5.385   -17.184 -48.543 1.00 114.72 ? 313 GLU B OE2 1 
ATOM   5682  N N   . ARG B 1 314 ? 4.830   -14.302 -42.550 1.00 74.67  ? 314 ARG B N   1 
ATOM   5683  C CA  . ARG B 1 314 ? 5.278   -13.132 -41.823 1.00 72.58  ? 314 ARG B CA  1 
ATOM   5684  C C   . ARG B 1 314 ? 6.535   -13.461 -41.027 1.00 67.75  ? 314 ARG B C   1 
ATOM   5685  O O   . ARG B 1 314 ? 7.421   -12.608 -40.884 1.00 68.97  ? 314 ARG B O   1 
ATOM   5686  C CB  . ARG B 1 314 ? 4.181   -12.635 -40.888 1.00 77.96  ? 314 ARG B CB  1 
ATOM   5687  C CG  . ARG B 1 314 ? 3.239   -11.630 -41.531 1.00 84.29  ? 314 ARG B CG  1 
ATOM   5688  C CD  . ARG B 1 314 ? 1.994   -11.424 -40.693 1.00 88.45  ? 314 ARG B CD  1 
ATOM   5689  N NE  . ARG B 1 314 ? 1.532   -10.029 -40.698 1.00 93.66  ? 314 ARG B NE  1 
ATOM   5690  C CZ  . ARG B 1 314 ? 2.132   -9.006  -40.075 1.00 95.52  ? 314 ARG B CZ  1 
ATOM   5691  N NH1 . ARG B 1 314 ? 3.310   -9.170  -39.492 1.00 96.19  ? 314 ARG B NH1 1 
ATOM   5692  N NH2 . ARG B 1 314 ? 1.557   -7.817  -40.058 1.00 95.55  ? 314 ARG B NH2 1 
ATOM   5693  N N   . VAL B 1 315 ? 6.596   -14.689 -40.486 1.00 61.65  ? 315 VAL B N   1 
ATOM   5694  C CA  . VAL B 1 315 ? 7.722   -15.101 -39.658 1.00 64.50  ? 315 VAL B CA  1 
ATOM   5695  C C   . VAL B 1 315 ? 9.002   -14.992 -40.486 1.00 74.35  ? 315 VAL B C   1 
ATOM   5696  O O   . VAL B 1 315 ? 10.035  -14.531 -39.983 1.00 71.39  ? 315 VAL B O   1 
ATOM   5697  C CB  . VAL B 1 315 ? 7.542   -16.520 -39.083 1.00 61.22  ? 315 VAL B CB  1 
ATOM   5698  C CG1 . VAL B 1 315 ? 8.862   -17.118 -38.640 1.00 64.19  ? 315 VAL B CG1 1 
ATOM   5699  C CG2 . VAL B 1 315 ? 6.540   -16.546 -37.934 1.00 61.13  ? 315 VAL B CG2 1 
ATOM   5700  N N   . LYS B 1 316 ? 8.910   -15.399 -41.772 1.00 87.77  ? 316 LYS B N   1 
ATOM   5701  C CA  . LYS B 1 316 ? 10.042  -15.357 -42.694 1.00 81.61  ? 316 LYS B CA  1 
ATOM   5702  C C   . LYS B 1 316 ? 10.539  -13.919 -42.856 1.00 76.53  ? 316 LYS B C   1 
ATOM   5703  O O   . LYS B 1 316 ? 11.733  -13.696 -43.065 1.00 71.73  ? 316 LYS B O   1 
ATOM   5704  C CB  . LYS B 1 316 ? 9.654   -15.961 -44.044 1.00 84.80  ? 316 LYS B CB  1 
ATOM   5705  C CG  . LYS B 1 316 ? 9.700   -17.474 -44.081 1.00 89.47  ? 316 LYS B CG  1 
ATOM   5706  C CD  . LYS B 1 316 ? 9.173   -18.072 -45.378 1.00 91.05  ? 316 LYS B CD  1 
ATOM   5707  C CE  . LYS B 1 316 ? 9.559   -19.503 -45.533 1.00 91.18  ? 316 LYS B CE  1 
ATOM   5708  N NZ  . LYS B 1 316 ? 8.815   -20.154 -46.605 1.00 91.97  ? 316 LYS B NZ  1 
ATOM   5709  N N   . GLY B 1 317 ? 9.618   -12.949 -42.729 1.00 67.00  ? 317 GLY B N   1 
ATOM   5710  C CA  . GLY B 1 317 ? 9.938   -11.541 -42.934 1.00 71.58  ? 317 GLY B CA  1 
ATOM   5711  C C   . GLY B 1 317 ? 10.793  -10.956 -41.797 1.00 73.87  ? 317 GLY B C   1 
ATOM   5712  O O   . GLY B 1 317 ? 11.454  -9.939  -41.983 1.00 72.87  ? 317 GLY B O   1 
ATOM   5713  N N   . LEU B 1 318 ? 10.740  -11.582 -40.612 1.00 77.45  ? 318 LEU B N   1 
ATOM   5714  C CA  . LEU B 1 318 ? 11.431  -11.061 -39.431 1.00 69.26  ? 318 LEU B CA  1 
ATOM   5715  C C   . LEU B 1 318 ? 12.937  -11.146 -39.657 1.00 60.27  ? 318 LEU B C   1 
ATOM   5716  O O   . LEU B 1 318 ? 13.446  -12.192 -40.031 1.00 62.12  ? 318 LEU B O   1 
ATOM   5717  C CB  . LEU B 1 318 ? 11.028  -11.844 -38.177 1.00 64.84  ? 318 LEU B CB  1 
ATOM   5718  C CG  . LEU B 1 318 ? 9.526   -11.952 -37.890 1.00 62.05  ? 318 LEU B CG  1 
ATOM   5719  C CD1 . LEU B 1 318 ? 9.265   -13.080 -36.882 1.00 60.26  ? 318 LEU B CD1 1 
ATOM   5720  C CD2 . LEU B 1 318 ? 8.935   -10.609 -37.401 1.00 54.12  ? 318 LEU B CD2 1 
ATOM   5721  N N   . ARG B 1 319 ? 13.637  -10.062 -39.355 1.00 58.36  ? 319 ARG B N   1 
ATOM   5722  C CA  . ARG B 1 319 ? 15.075  -10.005 -39.541 1.00 70.22  ? 319 ARG B CA  1 
ATOM   5723  C C   . ARG B 1 319 ? 15.785  -10.431 -38.256 1.00 70.13  ? 319 ARG B C   1 
ATOM   5724  O O   . ARG B 1 319 ? 15.486  -9.929  -37.175 1.00 60.21  ? 319 ARG B O   1 
ATOM   5725  C CB  . ARG B 1 319 ? 15.525  -8.609  -39.976 1.00 78.95  ? 319 ARG B CB  1 
ATOM   5726  C CG  . ARG B 1 319 ? 14.792  -7.456  -39.317 1.00 83.03  ? 319 ARG B CG  1 
ATOM   5727  C CD  . ARG B 1 319 ? 15.067  -6.164  -40.050 1.00 95.11  ? 319 ARG B CD  1 
ATOM   5728  N NE  . ARG B 1 319 ? 14.445  -6.138  -41.384 1.00 103.96 ? 319 ARG B NE  1 
ATOM   5729  C CZ  . ARG B 1 319 ? 13.582  -5.206  -41.817 1.00 111.04 ? 319 ARG B CZ  1 
ATOM   5730  N NH1 . ARG B 1 319 ? 13.240  -4.197  -41.032 1.00 119.34 ? 319 ARG B NH1 1 
ATOM   5731  N NH2 . ARG B 1 319 ? 13.070  -5.291  -43.034 1.00 102.22 ? 319 ARG B NH2 1 
ATOM   5732  N N   . VAL B 1 320 ? 16.749  -11.349 -38.417 1.00 71.89  ? 320 VAL B N   1 
ATOM   5733  C CA  . VAL B 1 320 ? 17.642  -11.771 -37.356 1.00 64.26  ? 320 VAL B CA  1 
ATOM   5734  C C   . VAL B 1 320 ? 18.950  -11.000 -37.491 1.00 71.71  ? 320 VAL B C   1 
ATOM   5735  O O   . VAL B 1 320 ? 19.616  -11.097 -38.518 1.00 92.76  ? 320 VAL B O   1 
ATOM   5736  C CB  . VAL B 1 320 ? 17.869  -13.289 -37.463 1.00 58.78  ? 320 VAL B CB  1 
ATOM   5737  C CG1 . VAL B 1 320 ? 18.576  -13.850 -36.241 1.00 59.29  ? 320 VAL B CG1 1 
ATOM   5738  C CG2 . VAL B 1 320 ? 16.562  -14.033 -37.713 1.00 59.68  ? 320 VAL B CG2 1 
ATOM   5739  N N   . GLY B 1 321 ? 19.310  -10.215 -36.464 1.00 71.91  ? 321 GLY B N   1 
ATOM   5740  C CA  . GLY B 1 321 ? 20.477  -9.353  -36.577 1.00 71.04  ? 321 GLY B CA  1 
ATOM   5741  C C   . GLY B 1 321 ? 20.958  -8.795  -35.237 1.00 71.17  ? 321 GLY B C   1 
ATOM   5742  O O   . GLY B 1 321 ? 20.666  -9.337  -34.167 1.00 75.72  ? 321 GLY B O   1 
ATOM   5743  N N   . ASP B 1 322 ? 21.752  -7.729  -35.340 1.00 65.94  ? 322 ASP B N   1 
ATOM   5744  C CA  . ASP B 1 322 ? 22.362  -7.080  -34.206 1.00 65.39  ? 322 ASP B CA  1 
ATOM   5745  C C   . ASP B 1 322 ? 21.271  -6.385  -33.392 1.00 65.73  ? 322 ASP B C   1 
ATOM   5746  O O   . ASP B 1 322 ? 20.520  -5.584  -33.934 1.00 58.65  ? 322 ASP B O   1 
ATOM   5747  C CB  . ASP B 1 322 ? 23.447  -6.115  -34.668 1.00 64.54  ? 322 ASP B CB  1 
ATOM   5748  C CG  . ASP B 1 322 ? 23.872  -5.071  -33.652 1.00 70.50  ? 322 ASP B CG  1 
ATOM   5749  O OD1 . ASP B 1 322 ? 24.047  -5.434  -32.481 1.00 69.97  ? 322 ASP B OD1 1 
ATOM   5750  O OD2 . ASP B 1 322 ? 24.003  -3.904  -34.041 1.00 81.62  ? 322 ASP B OD2 1 
ATOM   5751  N N   . PRO B 1 323 ? 21.183  -6.637  -32.053 1.00 66.02  ? 323 PRO B N   1 
ATOM   5752  C CA  . PRO B 1 323 ? 20.089  -6.108  -31.237 1.00 59.59  ? 323 PRO B CA  1 
ATOM   5753  C C   . PRO B 1 323 ? 20.107  -4.593  -31.092 1.00 58.43  ? 323 PRO B C   1 
ATOM   5754  O O   . PRO B 1 323 ? 19.107  -3.992  -30.713 1.00 54.86  ? 323 PRO B O   1 
ATOM   5755  C CB  . PRO B 1 323 ? 20.275  -6.806  -29.867 1.00 66.04  ? 323 PRO B CB  1 
ATOM   5756  C CG  . PRO B 1 323 ? 21.236  -7.937  -30.143 1.00 67.50  ? 323 PRO B CG  1 
ATOM   5757  C CD  . PRO B 1 323 ? 22.105  -7.474  -31.278 1.00 68.23  ? 323 PRO B CD  1 
ATOM   5758  N N   . GLN B 1 324 ? 21.260  -3.978  -31.357 1.00 57.92  ? 324 GLN B N   1 
ATOM   5759  C CA  . GLN B 1 324 ? 21.366  -2.531  -31.245 1.00 58.71  ? 324 GLN B CA  1 
ATOM   5760  C C   . GLN B 1 324 ? 20.527  -1.862  -32.331 1.00 55.14  ? 324 GLN B C   1 
ATOM   5761  O O   . GLN B 1 324 ? 20.114  -0.733  -32.171 1.00 53.41  ? 324 GLN B O   1 
ATOM   5762  C CB  . GLN B 1 324 ? 22.824  -2.075  -31.294 1.00 63.53  ? 324 GLN B CB  1 
ATOM   5763  C CG  . GLN B 1 324 ? 23.571  -2.248  -29.971 1.00 61.89  ? 324 GLN B CG  1 
ATOM   5764  C CD  . GLN B 1 324 ? 23.241  -1.174  -28.944 1.00 58.86  ? 324 GLN B CD  1 
ATOM   5765  O OE1 . GLN B 1 324 ? 22.835  -0.066  -29.280 1.00 53.44  ? 324 GLN B OE1 1 
ATOM   5766  N NE2 . GLN B 1 324 ? 23.475  -1.482  -27.677 1.00 67.51  ? 324 GLN B NE2 1 
ATOM   5767  N N   . ARG B 1 325 ? 20.307  -2.567  -33.444 1.00 63.46  ? 325 ARG B N   1 
ATOM   5768  C CA  . ARG B 1 325 ? 19.563  -2.007  -34.563 1.00 72.76  ? 325 ARG B CA  1 
ATOM   5769  C C   . ARG B 1 325 ? 18.081  -1.946  -34.200 1.00 61.61  ? 325 ARG B C   1 
ATOM   5770  O O   . ARG B 1 325 ? 17.513  -2.933  -33.729 1.00 58.90  ? 325 ARG B O   1 
ATOM   5771  C CB  . ARG B 1 325 ? 19.766  -2.823  -35.853 1.00 89.35  ? 325 ARG B CB  1 
ATOM   5772  C CG  . ARG B 1 325 ? 21.130  -2.677  -36.525 1.00 98.68  ? 325 ARG B CG  1 
ATOM   5773  C CD  . ARG B 1 325 ? 21.221  -3.493  -37.847 1.00 104.46 ? 325 ARG B CD  1 
ATOM   5774  N NE  . ARG B 1 325 ? 20.322  -2.984  -38.896 1.00 103.59 ? 325 ARG B NE  1 
ATOM   5775  C CZ  . ARG B 1 325 ? 20.481  -1.826  -39.553 1.00 97.29  ? 325 ARG B CZ  1 
ATOM   5776  N NH1 . ARG B 1 325 ? 21.593  -1.119  -39.414 1.00 94.21  ? 325 ARG B NH1 1 
ATOM   5777  N NH2 . ARG B 1 325 ? 19.535  -1.397  -40.372 1.00 89.25  ? 325 ARG B NH2 1 
ATOM   5778  N N   . ALA B 1 326 ? 17.462  -0.785  -34.484 1.00 51.30  ? 326 ALA B N   1 
ATOM   5779  C CA  . ALA B 1 326 ? 16.065  -0.527  -34.161 1.00 52.69  ? 326 ALA B CA  1 
ATOM   5780  C C   . ALA B 1 326 ? 15.139  -1.419  -34.994 1.00 58.08  ? 326 ALA B C   1 
ATOM   5781  O O   . ALA B 1 326 ? 14.012  -1.692  -34.588 1.00 58.42  ? 326 ALA B O   1 
ATOM   5782  C CB  . ALA B 1 326 ? 15.751  0.941   -34.376 1.00 51.93  ? 326 ALA B CB  1 
ATOM   5783  N N   . ASP B 1 327 ? 15.626  -1.884  -36.144 1.00 66.43  ? 327 ASP B N   1 
ATOM   5784  C CA  . ASP B 1 327 ? 14.795  -2.638  -37.076 1.00 75.67  ? 327 ASP B CA  1 
ATOM   5785  C C   . ASP B 1 327 ? 14.820  -4.135  -36.734 1.00 72.54  ? 327 ASP B C   1 
ATOM   5786  O O   . ASP B 1 327 ? 14.031  -4.899  -37.274 1.00 82.02  ? 327 ASP B O   1 
ATOM   5787  C CB  . ASP B 1 327 ? 15.235  -2.402  -38.510 1.00 87.81  ? 327 ASP B CB  1 
ATOM   5788  C CG  . ASP B 1 327 ? 16.589  -2.992  -38.867 1.00 93.37  ? 327 ASP B CG  1 
ATOM   5789  O OD1 . ASP B 1 327 ? 17.454  -3.048  -37.972 1.00 95.87  ? 327 ASP B OD1 1 
ATOM   5790  O OD2 . ASP B 1 327 ? 16.759  -3.395  -40.029 1.00 94.55  ? 327 ASP B OD2 1 
ATOM   5791  N N   . THR B 1 328 ? 15.754  -4.558  -35.863 1.00 66.54  ? 328 THR B N   1 
ATOM   5792  C CA  . THR B 1 328 ? 15.962  -5.987  -35.609 1.00 58.85  ? 328 THR B CA  1 
ATOM   5793  C C   . THR B 1 328 ? 14.780  -6.559  -34.813 1.00 61.01  ? 328 THR B C   1 
ATOM   5794  O O   . THR B 1 328 ? 14.469  -6.084  -33.726 1.00 56.46  ? 328 THR B O   1 
ATOM   5795  C CB  . THR B 1 328 ? 17.271  -6.209  -34.867 1.00 63.13  ? 328 THR B CB  1 
ATOM   5796  O OG1 . THR B 1 328 ? 18.325  -5.960  -35.789 1.00 73.35  ? 328 THR B OG1 1 
ATOM   5797  C CG2 . THR B 1 328 ? 17.396  -7.629  -34.345 1.00 64.65  ? 328 THR B CG2 1 
ATOM   5798  N N   . ALA B 1 329 ? 14.198  -7.648  -35.325 1.00 59.46  ? 329 ALA B N   1 
ATOM   5799  C CA  . ALA B 1 329 ? 13.097  -8.322  -34.653 1.00 65.03  ? 329 ALA B CA  1 
ATOM   5800  C C   . ALA B 1 329 ? 13.622  -9.403  -33.698 1.00 61.65  ? 329 ALA B C   1 
ATOM   5801  O O   . ALA B 1 329 ? 13.140  -9.512  -32.581 1.00 66.01  ? 329 ALA B O   1 
ATOM   5802  C CB  . ALA B 1 329 ? 12.142  -8.915  -35.677 1.00 70.15  ? 329 ALA B CB  1 
ATOM   5803  N N   . VAL B 1 330 ? 14.551  -10.250 -34.178 1.00 58.64  ? 330 VAL B N   1 
ATOM   5804  C CA  . VAL B 1 330 ? 15.049  -11.375 -33.387 1.00 53.00  ? 330 VAL B CA  1 
ATOM   5805  C C   . VAL B 1 330 ? 16.557  -11.206 -33.143 1.00 56.18  ? 330 VAL B C   1 
ATOM   5806  O O   . VAL B 1 330 ? 17.309  -10.865 -34.046 1.00 60.82  ? 330 VAL B O   1 
ATOM   5807  C CB  . VAL B 1 330 ? 14.742  -12.741 -34.025 1.00 54.03  ? 330 VAL B CB  1 
ATOM   5808  C CG1 . VAL B 1 330 ? 15.445  -13.887 -33.294 1.00 50.29  ? 330 VAL B CG1 1 
ATOM   5809  C CG2 . VAL B 1 330 ? 13.236  -13.008 -34.112 1.00 55.31  ? 330 VAL B CG2 1 
ATOM   5810  N N   . GLY B 1 331 ? 16.978  -11.484 -31.901 1.00 54.11  ? 331 GLY B N   1 
ATOM   5811  C CA  . GLY B 1 331 ? 18.343  -11.273 -31.479 1.00 48.30  ? 331 GLY B CA  1 
ATOM   5812  C C   . GLY B 1 331 ? 18.945  -12.554 -30.917 1.00 47.93  ? 331 GLY B C   1 
ATOM   5813  O O   . GLY B 1 331 ? 18.375  -13.652 -31.060 1.00 52.20  ? 331 GLY B O   1 
ATOM   5814  N N   . PRO B 1 332 ? 20.095  -12.454 -30.232 1.00 46.02  ? 332 PRO B N   1 
ATOM   5815  C CA  . PRO B 1 332 ? 20.805  -13.639 -29.737 1.00 52.87  ? 332 PRO B CA  1 
ATOM   5816  C C   . PRO B 1 332 ? 20.228  -14.201 -28.446 1.00 53.87  ? 332 PRO B C   1 
ATOM   5817  O O   . PRO B 1 332 ? 19.636  -13.473 -27.660 1.00 67.10  ? 332 PRO B O   1 
ATOM   5818  C CB  . PRO B 1 332 ? 22.223  -13.096 -29.540 1.00 50.88  ? 332 PRO B CB  1 
ATOM   5819  C CG  . PRO B 1 332 ? 21.993  -11.647 -29.118 1.00 47.02  ? 332 PRO B CG  1 
ATOM   5820  C CD  . PRO B 1 332 ? 20.774  -11.202 -29.911 1.00 43.38  ? 332 PRO B CD  1 
ATOM   5821  N N   . ILE B 1 333 ? 20.453  -15.494 -28.230 1.00 55.83  ? 333 ILE B N   1 
ATOM   5822  C CA  . ILE B 1 333 ? 20.110  -16.148 -26.981 1.00 55.00  ? 333 ILE B CA  1 
ATOM   5823  C C   . ILE B 1 333 ? 21.109  -15.705 -25.914 1.00 56.34  ? 333 ILE B C   1 
ATOM   5824  O O   . ILE B 1 333 ? 22.252  -15.371 -26.230 1.00 58.22  ? 333 ILE B O   1 
ATOM   5825  C CB  . ILE B 1 333 ? 20.077  -17.672 -27.170 1.00 56.28  ? 333 ILE B CB  1 
ATOM   5826  C CG1 . ILE B 1 333 ? 19.215  -18.058 -28.383 1.00 64.76  ? 333 ILE B CG1 1 
ATOM   5827  C CG2 . ILE B 1 333 ? 19.616  -18.401 -25.897 1.00 59.38  ? 333 ILE B CG2 1 
ATOM   5828  C CD1 . ILE B 1 333 ? 17.764  -17.600 -28.292 1.00 59.63  ? 333 ILE B CD1 1 
ATOM   5829  N N   . VAL B 1 334 ? 20.649  -15.695 -24.655 1.00 52.05  ? 334 VAL B N   1 
ATOM   5830  C CA  . VAL B 1 334 ? 21.351  -15.035 -23.555 1.00 56.67  ? 334 VAL B CA  1 
ATOM   5831  C C   . VAL B 1 334 ? 22.709  -15.724 -23.294 1.00 57.55  ? 334 VAL B C   1 
ATOM   5832  O O   . VAL B 1 334 ? 23.711  -15.041 -23.101 1.00 53.91  ? 334 VAL B O   1 
ATOM   5833  C CB  . VAL B 1 334 ? 20.481  -14.995 -22.272 1.00 51.86  ? 334 VAL B CB  1 
ATOM   5834  C CG1 . VAL B 1 334 ? 19.941  -16.378 -21.887 1.00 51.60  ? 334 VAL B CG1 1 
ATOM   5835  C CG2 . VAL B 1 334 ? 21.229  -14.372 -21.102 1.00 49.65  ? 334 VAL B CG2 1 
ATOM   5836  N N   . ASN B 1 335 ? 22.698  -17.062 -23.305 1.00 55.41  ? 335 ASN B N   1 
ATOM   5837  C CA  . ASN B 1 335 ? 23.929  -17.852 -23.036 1.00 56.72  ? 335 ASN B CA  1 
ATOM   5838  C C   . ASN B 1 335 ? 23.911  -19.123 -23.889 1.00 66.06  ? 335 ASN B C   1 
ATOM   5839  O O   . ASN B 1 335 ? 22.838  -19.458 -24.434 1.00 64.86  ? 335 ASN B O   1 
ATOM   5840  C CB  . ASN B 1 335 ? 24.074  -18.178 -21.553 1.00 58.50  ? 335 ASN B CB  1 
ATOM   5841  C CG  . ASN B 1 335 ? 22.892  -18.930 -20.991 1.00 61.62  ? 335 ASN B CG  1 
ATOM   5842  O OD1 . ASN B 1 335 ? 22.681  -20.102 -21.319 1.00 64.45  ? 335 ASN B OD1 1 
ATOM   5843  N ND2 . ASN B 1 335 ? 22.129  -18.287 -20.122 1.00 65.21  ? 335 ASN B ND2 1 
ATOM   5844  N N   . ALA B 1 336 ? 25.053  -19.806 -23.992 1.00 74.08  ? 336 ALA B N   1 
ATOM   5845  C CA  . ALA B 1 336 ? 25.166  -21.032 -24.819 1.00 70.63  ? 336 ALA B CA  1 
ATOM   5846  C C   . ALA B 1 336 ? 24.262  -22.151 -24.298 1.00 66.02  ? 336 ALA B C   1 
ATOM   5847  O O   . ALA B 1 336 ? 23.680  -22.873 -25.128 1.00 75.41  ? 336 ALA B O   1 
ATOM   5848  C CB  . ALA B 1 336 ? 26.608  -21.474 -24.865 1.00 67.12  ? 336 ALA B CB  1 
ATOM   5849  N N   . ARG B 1 337 ? 24.168  -22.319 -22.978 1.00 70.55  ? 337 ARG B N   1 
ATOM   5850  C CA  . ARG B 1 337 ? 23.387  -23.459 -22.428 1.00 70.15  ? 337 ARG B CA  1 
ATOM   5851  C C   . ARG B 1 337 ? 21.913  -23.319 -22.838 1.00 70.93  ? 337 ARG B C   1 
ATOM   5852  O O   . ARG B 1 337 ? 21.307  -24.338 -23.229 1.00 73.14  ? 337 ARG B O   1 
ATOM   5853  C CB  . ARG B 1 337 ? 23.555  -23.512 -20.906 1.00 78.35  ? 337 ARG B CB  1 
ATOM   5854  N N   . GLN B 1 338 ? 21.375  -22.100 -22.789 1.00 67.30  ? 338 GLN B N   1 
ATOM   5855  C CA  . GLN B 1 338 ? 19.972  -21.875 -23.212 1.00 64.28  ? 338 GLN B CA  1 
ATOM   5856  C C   . GLN B 1 338 ? 19.843  -22.214 -24.703 1.00 67.89  ? 338 GLN B C   1 
ATOM   5857  O O   . GLN B 1 338 ? 18.850  -22.873 -25.079 1.00 65.43  ? 338 GLN B O   1 
ATOM   5858  C CB  . GLN B 1 338 ? 19.593  -20.425 -22.916 1.00 61.06  ? 338 GLN B CB  1 
ATOM   5859  C CG  . GLN B 1 338 ? 19.147  -20.184 -21.480 1.00 59.44  ? 338 GLN B CG  1 
ATOM   5860  C CD  . GLN B 1 338 ? 17.969  -21.044 -21.077 1.00 62.14  ? 338 GLN B CD  1 
ATOM   5861  O OE1 . GLN B 1 338 ? 18.037  -21.822 -20.120 1.00 61.62  ? 338 GLN B OE1 1 
ATOM   5862  N NE2 . GLN B 1 338 ? 16.871  -20.906 -21.806 1.00 61.41  ? 338 GLN B NE2 1 
ATOM   5863  N N   . LEU B 1 339 ? 20.833  -21.817 -25.504 1.00 67.63  ? 339 LEU B N   1 
ATOM   5864  C CA  . LEU B 1 339 ? 20.802  -22.092 -26.963 1.00 72.36  ? 339 LEU B CA  1 
ATOM   5865  C C   . LEU B 1 339 ? 20.825  -23.609 -27.185 1.00 74.72  ? 339 LEU B C   1 
ATOM   5866  O O   . LEU B 1 339 ? 20.081  -24.095 -28.059 1.00 75.33  ? 339 LEU B O   1 
ATOM   5867  C CB  . LEU B 1 339 ? 22.000  -21.410 -27.616 1.00 74.95  ? 339 LEU B CB  1 
ATOM   5868  C CG  . LEU B 1 339 ? 22.176  -21.649 -29.117 1.00 84.55  ? 339 LEU B CG  1 
ATOM   5869  C CD1 . LEU B 1 339 ? 20.990  -21.103 -29.891 1.00 90.19  ? 339 LEU B CD1 1 
ATOM   5870  C CD2 . LEU B 1 339 ? 23.463  -21.002 -29.585 1.00 90.82  ? 339 LEU B CD2 1 
ATOM   5871  N N   . GLU B 1 340 ? 21.633  -24.323 -26.401 1.00 77.10  ? 340 GLU B N   1 
ATOM   5872  C CA  . GLU B 1 340 ? 21.757  -25.791 -26.566 1.00 84.60  ? 340 GLU B CA  1 
ATOM   5873  C C   . GLU B 1 340 ? 20.395  -26.444 -26.284 1.00 83.60  ? 340 GLU B C   1 
ATOM   5874  O O   . GLU B 1 340 ? 20.010  -27.361 -27.038 1.00 87.80  ? 340 GLU B O   1 
ATOM   5875  C CB  . GLU B 1 340 ? 22.871  -26.282 -25.641 1.00 96.60  ? 340 GLU B CB  1 
ATOM   5876  N N   . GLY B 1 341 ? 19.687  -25.965 -25.257 1.00 76.32  ? 341 GLY B N   1 
ATOM   5877  C CA  . GLY B 1 341 ? 18.374  -26.539 -24.913 1.00 66.39  ? 341 GLY B CA  1 
ATOM   5878  C C   . GLY B 1 341 ? 17.397  -26.339 -26.049 1.00 68.73  ? 341 GLY B C   1 
ATOM   5879  O O   . GLY B 1 341 ? 16.633  -27.276 -26.347 1.00 68.75  ? 341 GLY B O   1 
ATOM   5880  N N   . LEU B 1 342 ? 17.433  -25.162 -26.672 1.00 66.10  ? 342 LEU B N   1 
ATOM   5881  C CA  . LEU B 1 342 ? 16.538  -24.877 -27.818 1.00 65.17  ? 342 LEU B CA  1 
ATOM   5882  C C   . LEU B 1 342 ? 16.911  -25.805 -28.982 1.00 66.51  ? 342 LEU B C   1 
ATOM   5883  O O   . LEU B 1 342 ? 15.992  -26.363 -29.611 1.00 67.36  ? 342 LEU B O   1 
ATOM   5884  C CB  . LEU B 1 342 ? 16.663  -23.404 -28.192 1.00 64.28  ? 342 LEU B CB  1 
ATOM   5885  C CG  . LEU B 1 342 ? 15.947  -22.427 -27.256 1.00 62.91  ? 342 LEU B CG  1 
ATOM   5886  C CD1 . LEU B 1 342 ? 16.625  -21.070 -27.248 1.00 62.52  ? 342 LEU B CD1 1 
ATOM   5887  C CD2 . LEU B 1 342 ? 14.489  -22.304 -27.651 1.00 64.74  ? 342 LEU B CD2 1 
ATOM   5888  N N   . LEU B 1 343 ? 18.209  -25.971 -29.241 1.00 71.92  ? 343 LEU B N   1 
ATOM   5889  C CA  . LEU B 1 343 ? 18.635  -26.825 -30.345 1.00 68.89  ? 343 LEU B CA  1 
ATOM   5890  C C   . LEU B 1 343 ? 18.191  -28.266 -30.100 1.00 65.50  ? 343 LEU B C   1 
ATOM   5891  O O   . LEU B 1 343 ? 17.808  -28.959 -31.035 1.00 65.28  ? 343 LEU B O   1 
ATOM   5892  C CB  . LEU B 1 343 ? 20.141  -26.730 -30.536 1.00 69.41  ? 343 LEU B CB  1 
ATOM   5893  C CG  . LEU B 1 343 ? 20.653  -25.408 -31.106 1.00 77.75  ? 343 LEU B CG  1 
ATOM   5894  C CD1 . LEU B 1 343 ? 22.072  -25.568 -31.624 1.00 81.92  ? 343 LEU B CD1 1 
ATOM   5895  C CD2 . LEU B 1 343 ? 19.727  -24.873 -32.201 1.00 76.46  ? 343 LEU B CD2 1 
ATOM   5896  N N   . GLU B 1 344 ? 18.217  -28.699 -28.838 1.00 66.43  ? 344 GLU B N   1 
ATOM   5897  C CA  . GLU B 1 344 ? 17.754  -30.037 -28.489 1.00 72.82  ? 344 GLU B CA  1 
ATOM   5898  C C   . GLU B 1 344 ? 16.239  -30.134 -28.697 1.00 75.63  ? 344 GLU B C   1 
ATOM   5899  O O   . GLU B 1 344 ? 15.737  -31.176 -29.113 1.00 90.54  ? 344 GLU B O   1 
ATOM   5900  C CB  . GLU B 1 344 ? 18.137  -30.408 -27.054 1.00 78.31  ? 344 GLU B CB  1 
ATOM   5901  N N   . LYS B 1 345 ? 15.520  -29.042 -28.394 1.00 74.93  ? 345 LYS B N   1 
ATOM   5902  C CA  . LYS B 1 345 ? 14.066  -29.019 -28.506 1.00 75.72  ? 345 LYS B CA  1 
ATOM   5903  C C   . LYS B 1 345 ? 13.654  -29.154 -29.974 1.00 67.94  ? 345 LYS B C   1 
ATOM   5904  O O   . LYS B 1 345 ? 12.700  -29.858 -30.276 1.00 64.77  ? 345 LYS B O   1 
ATOM   5905  C CB  . LYS B 1 345 ? 13.470  -27.748 -27.891 1.00 78.37  ? 345 LYS B CB  1 
ATOM   5906  C CG  . LYS B 1 345 ? 13.222  -27.809 -26.397 1.00 78.08  ? 345 LYS B CG  1 
ATOM   5907  C CD  . LYS B 1 345 ? 13.078  -26.429 -25.743 1.00 78.59  ? 345 LYS B CD  1 
ATOM   5908  C CE  . LYS B 1 345 ? 12.691  -26.476 -24.292 1.00 73.09  ? 345 LYS B CE  1 
ATOM   5909  N NZ  . LYS B 1 345 ? 11.953  -27.700 -23.953 1.00 80.08  ? 345 LYS B NZ  1 
ATOM   5910  N N   . ILE B 1 346 ? 14.393  -28.481 -30.876 1.00 61.38  ? 346 ILE B N   1 
ATOM   5911  C CA  . ILE B 1 346 ? 14.119  -28.565 -32.304 1.00 66.78  ? 346 ILE B CA  1 
ATOM   5912  C C   . ILE B 1 346 ? 14.350  -30.007 -32.770 1.00 73.84  ? 346 ILE B C   1 
ATOM   5913  O O   . ILE B 1 346 ? 13.541  -30.562 -33.515 1.00 76.30  ? 346 ILE B O   1 
ATOM   5914  C CB  . ILE B 1 346 ? 14.971  -27.552 -33.100 1.00 65.34  ? 346 ILE B CB  1 
ATOM   5915  C CG1 . ILE B 1 346 ? 14.672  -26.113 -32.674 1.00 63.34  ? 346 ILE B CG1 1 
ATOM   5916  C CG2 . ILE B 1 346 ? 14.782  -27.729 -34.617 1.00 62.89  ? 346 ILE B CG2 1 
ATOM   5917  C CD1 . ILE B 1 346 ? 15.812  -25.146 -32.920 1.00 64.14  ? 346 ILE B CD1 1 
ATOM   5918  N N   . ARG B 1 347 ? 15.437  -30.612 -32.292 1.00 79.10  ? 347 ARG B N   1 
ATOM   5919  C CA  . ARG B 1 347 ? 15.810  -31.962 -32.687 1.00 83.04  ? 347 ARG B CA  1 
ATOM   5920  C C   . ARG B 1 347 ? 14.711  -32.944 -32.266 1.00 79.95  ? 347 ARG B C   1 
ATOM   5921  O O   . ARG B 1 347 ? 14.299  -33.806 -33.059 1.00 82.54  ? 347 ARG B O   1 
ATOM   5922  C CB  . ARG B 1 347 ? 17.182  -32.324 -32.091 1.00 91.04  ? 347 ARG B CB  1 
ATOM   5923  C CG  . ARG B 1 347 ? 17.459  -33.818 -31.961 1.00 102.82 ? 347 ARG B CG  1 
ATOM   5924  C CD  . ARG B 1 347 ? 18.789  -34.200 -32.595 1.00 114.64 ? 347 ARG B CD  1 
ATOM   5925  N NE  . ARG B 1 347 ? 18.815  -33.897 -34.040 1.00 129.06 ? 347 ARG B NE  1 
ATOM   5926  C CZ  . ARG B 1 347 ? 18.159  -34.571 -35.018 1.00 110.70 ? 347 ARG B CZ  1 
ATOM   5927  N NH1 . ARG B 1 347 ? 17.551  -35.726 -34.758 1.00 97.55  ? 347 ARG B NH1 1 
ATOM   5928  N NH2 . ARG B 1 347 ? 18.152  -34.088 -36.258 1.00 97.04  ? 347 ARG B NH2 1 
ATOM   5929  N N   . LEU B 1 348 ? 14.260  -32.831 -31.014 1.00 71.12  ? 348 LEU B N   1 
ATOM   5930  C CA  . LEU B 1 348 ? 13.301  -33.777 -30.470 1.00 72.48  ? 348 LEU B CA  1 
ATOM   5931  C C   . LEU B 1 348 ? 11.968  -33.654 -31.218 1.00 75.81  ? 348 LEU B C   1 
ATOM   5932  O O   . LEU B 1 348 ? 11.248  -34.643 -31.386 1.00 74.64  ? 348 LEU B O   1 
ATOM   5933  C CB  . LEU B 1 348 ? 13.115  -33.559 -28.974 1.00 73.30  ? 348 LEU B CB  1 
ATOM   5934  C CG  . LEU B 1 348 ? 12.140  -34.521 -28.289 1.00 76.16  ? 348 LEU B CG  1 
ATOM   5935  C CD1 . LEU B 1 348 ? 12.582  -35.958 -28.515 1.00 83.64  ? 348 LEU B CD1 1 
ATOM   5936  C CD2 . LEU B 1 348 ? 12.009  -34.232 -26.810 1.00 74.07  ? 348 LEU B CD2 1 
ATOM   5937  N N   . ALA B 1 349 ? 11.636  -32.431 -31.650 1.00 73.94  ? 349 ALA B N   1 
ATOM   5938  C CA  . ALA B 1 349 ? 10.350  -32.178 -32.285 1.00 78.96  ? 349 ALA B CA  1 
ATOM   5939  C C   . ALA B 1 349 ? 10.210  -33.032 -33.548 1.00 81.53  ? 349 ALA B C   1 
ATOM   5940  O O   . ALA B 1 349 ? 9.153   -33.636 -33.771 1.00 79.74  ? 349 ALA B O   1 
ATOM   5941  C CB  . ALA B 1 349 ? 10.185  -30.705 -32.583 1.00 73.27  ? 349 ALA B CB  1 
ATOM   5942  N N   . ARG B 1 350 ? 11.288  -33.104 -34.350 1.00 76.87  ? 350 ARG B N   1 
ATOM   5943  C CA  . ARG B 1 350 ? 11.275  -33.874 -35.593 1.00 80.42  ? 350 ARG B CA  1 
ATOM   5944  C C   . ARG B 1 350 ? 11.116  -35.352 -35.255 1.00 80.33  ? 350 ARG B C   1 
ATOM   5945  O O   . ARG B 1 350 ? 10.271  -36.034 -35.820 1.00 79.27  ? 350 ARG B O   1 
ATOM   5946  C CB  . ARG B 1 350 ? 12.570  -33.707 -36.398 1.00 84.34  ? 350 ARG B CB  1 
ATOM   5947  C CG  . ARG B 1 350 ? 13.141  -32.303 -36.475 1.00 90.74  ? 350 ARG B CG  1 
ATOM   5948  C CD  . ARG B 1 350 ? 14.677  -32.343 -36.485 1.00 92.00  ? 350 ARG B CD  1 
ATOM   5949  N NE  . ARG B 1 350 ? 15.300  -31.029 -36.703 1.00 98.10  ? 350 ARG B NE  1 
ATOM   5950  C CZ  . ARG B 1 350 ? 15.433  -30.428 -37.887 1.00 97.01  ? 350 ARG B CZ  1 
ATOM   5951  N NH1 . ARG B 1 350 ? 14.930  -30.985 -38.973 1.00 103.69 ? 350 ARG B NH1 1 
ATOM   5952  N NH2 . ARG B 1 350 ? 16.071  -29.269 -37.979 1.00 95.14  ? 350 ARG B NH2 1 
ATOM   5953  N N   . GLN B 1 351 ? 12.040  -35.834 -34.415 1.00 81.78  ? 351 GLN B N   1 
ATOM   5954  C CA  . GLN B 1 351 ? 11.925  -37.074 -33.663 1.00 85.29  ? 351 GLN B CA  1 
ATOM   5955  C C   . GLN B 1 351 ? 10.473  -37.412 -33.252 1.00 82.75  ? 351 GLN B C   1 
ATOM   5956  O O   . GLN B 1 351 ? 10.081  -38.579 -33.333 1.00 97.16  ? 351 GLN B O   1 
ATOM   5957  C CB  . GLN B 1 351 ? 12.885  -36.968 -32.474 1.00 97.21  ? 351 GLN B CB  1 
ATOM   5958  C CG  . GLN B 1 351 ? 14.326  -37.286 -32.843 1.00 103.84 ? 351 GLN B CG  1 
ATOM   5959  C CD  . GLN B 1 351 ? 15.014  -38.148 -31.811 1.00 114.43 ? 351 GLN B CD  1 
ATOM   5960  O OE1 . GLN B 1 351 ? 14.529  -39.232 -31.445 1.00 102.38 ? 351 GLN B OE1 1 
ATOM   5961  N NE2 . GLN B 1 351 ? 16.142  -37.662 -31.309 1.00 122.73 ? 351 GLN B NE2 1 
ATOM   5962  N N   . GLU B 1 352 ? 9.710   -36.440 -32.719 1.00 84.48  ? 352 GLU B N   1 
ATOM   5963  C CA  . GLU B 1 352 ? 8.389   -36.750 -32.150 1.00 83.26  ? 352 GLU B CA  1 
ATOM   5964  C C   . GLU B 1 352 ? 7.295   -36.711 -33.243 1.00 77.14  ? 352 GLU B C   1 
ATOM   5965  O O   . GLU B 1 352 ? 6.148   -37.063 -32.983 1.00 70.04  ? 352 GLU B O   1 
ATOM   5966  C CB  . GLU B 1 352 ? 8.064   -35.807 -30.992 1.00 91.31  ? 352 GLU B CB  1 
ATOM   5967  C CG  . GLU B 1 352 ? 8.568   -36.293 -29.636 1.00 89.31  ? 352 GLU B CG  1 
ATOM   5968  C CD  . GLU B 1 352 ? 8.542   -35.228 -28.533 1.00 103.11 ? 352 GLU B CD  1 
ATOM   5969  O OE1 . GLU B 1 352 ? 8.530   -34.005 -28.850 1.00 118.51 ? 352 GLU B OE1 1 
ATOM   5970  O OE2 . GLU B 1 352 ? 8.530   -35.620 -27.351 1.00 106.68 ? 352 GLU B OE2 1 
ATOM   5971  N N   . GLY B 1 353 ? 7.659   -36.266 -34.456 1.00 80.86  ? 353 GLY B N   1 
ATOM   5972  C CA  . GLY B 1 353 ? 6.779   -36.372 -35.612 1.00 83.46  ? 353 GLY B CA  1 
ATOM   5973  C C   . GLY B 1 353 ? 6.151   -35.029 -36.004 1.00 83.21  ? 353 GLY B C   1 
ATOM   5974  O O   . GLY B 1 353 ? 5.213   -35.001 -36.785 1.00 81.70  ? 353 GLY B O   1 
ATOM   5975  N N   . ALA B 1 354 ? 6.701   -33.917 -35.496 1.00 83.39  ? 354 ALA B N   1 
ATOM   5976  C CA  . ALA B 1 354 ? 6.220   -32.589 -35.874 1.00 78.11  ? 354 ALA B CA  1 
ATOM   5977  C C   . ALA B 1 354 ? 6.669   -32.265 -37.288 1.00 76.85  ? 354 ALA B C   1 
ATOM   5978  O O   . ALA B 1 354 ? 7.798   -32.579 -37.676 1.00 68.90  ? 354 ALA B O   1 
ATOM   5979  C CB  . ALA B 1 354 ? 6.713   -31.541 -34.898 1.00 82.78  ? 354 ALA B CB  1 
ATOM   5980  N N   . LYS B 1 355 ? 5.793   -31.589 -38.036 1.00 75.54  ? 355 LYS B N   1 
ATOM   5981  C CA  . LYS B 1 355 ? 6.080   -31.237 -39.413 1.00 78.40  ? 355 LYS B CA  1 
ATOM   5982  C C   . LYS B 1 355 ? 6.787   -29.884 -39.450 1.00 74.75  ? 355 LYS B C   1 
ATOM   5983  O O   . LYS B 1 355 ? 6.210   -28.885 -39.048 1.00 72.86  ? 355 LYS B O   1 
ATOM   5984  C CB  . LYS B 1 355 ? 4.797   -31.203 -40.259 1.00 81.67  ? 355 LYS B CB  1 
ATOM   5985  C CG  . LYS B 1 355 ? 5.014   -30.682 -41.696 1.00 83.46  ? 355 LYS B CG  1 
ATOM   5986  C CD  . LYS B 1 355 ? 3.944   -31.095 -42.712 1.00 81.21  ? 355 LYS B CD  1 
ATOM   5987  C CE  . LYS B 1 355 ? 3.069   -29.955 -43.153 1.00 75.64  ? 355 LYS B CE  1 
ATOM   5988  N NZ  . LYS B 1 355 ? 1.659   -30.345 -43.172 1.00 75.90  ? 355 LYS B NZ  1 
ATOM   5989  N N   . PRO B 1 356 ? 8.027   -29.799 -39.991 1.00 69.88  ? 356 PRO B N   1 
ATOM   5990  C CA  . PRO B 1 356 ? 8.741   -28.533 -40.067 1.00 71.56  ? 356 PRO B CA  1 
ATOM   5991  C C   . PRO B 1 356 ? 8.130   -27.586 -41.090 1.00 75.73  ? 356 PRO B C   1 
ATOM   5992  O O   . PRO B 1 356 ? 8.321   -27.753 -42.288 1.00 85.26  ? 356 PRO B O   1 
ATOM   5993  C CB  . PRO B 1 356 ? 10.195  -28.958 -40.457 1.00 70.41  ? 356 PRO B CB  1 
ATOM   5994  C CG  . PRO B 1 356 ? 10.217  -30.478 -40.275 1.00 66.20  ? 356 PRO B CG  1 
ATOM   5995  C CD  . PRO B 1 356 ? 8.813   -30.915 -40.517 1.00 67.34  ? 356 PRO B CD  1 
ATOM   5996  N N   . LEU B 1 357 ? 7.432   -26.566 -40.605 1.00 71.90  ? 357 LEU B N   1 
ATOM   5997  C CA  . LEU B 1 357 ? 6.873   -25.551 -41.478 1.00 67.90  ? 357 LEU B CA  1 
ATOM   5998  C C   . LEU B 1 357 ? 7.962   -24.565 -41.883 1.00 64.38  ? 357 LEU B C   1 
ATOM   5999  O O   . LEU B 1 357 ? 8.031   -24.171 -43.028 1.00 67.12  ? 357 LEU B O   1 
ATOM   6000  C CB  . LEU B 1 357 ? 5.704   -24.842 -40.801 1.00 73.38  ? 357 LEU B CB  1 
ATOM   6001  C CG  . LEU B 1 357 ? 4.531   -25.730 -40.369 1.00 75.79  ? 357 LEU B CG  1 
ATOM   6002  C CD1 . LEU B 1 357 ? 3.300   -24.875 -40.046 1.00 72.07  ? 357 LEU B CD1 1 
ATOM   6003  C CD2 . LEU B 1 357 ? 4.205   -26.785 -41.432 1.00 76.47  ? 357 LEU B CD2 1 
ATOM   6004  N N   . TYR B 1 358 ? 8.755   -24.110 -40.913 1.00 70.04  ? 358 TYR B N   1 
ATOM   6005  C CA  . TYR B 1 358 ? 9.848   -23.187 -41.192 1.00 72.41  ? 358 TYR B CA  1 
ATOM   6006  C C   . TYR B 1 358 ? 11.036  -23.533 -40.307 1.00 77.84  ? 358 TYR B C   1 
ATOM   6007  O O   . TYR B 1 358 ? 10.874  -23.797 -39.118 1.00 86.94  ? 358 TYR B O   1 
ATOM   6008  C CB  . TYR B 1 358 ? 9.435   -21.728 -40.995 1.00 70.50  ? 358 TYR B CB  1 
ATOM   6009  C CG  . TYR B 1 358 ? 10.553  -20.742 -41.279 1.00 72.11  ? 358 TYR B CG  1 
ATOM   6010  C CD1 . TYR B 1 358 ? 11.107  -20.634 -42.550 1.00 70.04  ? 358 TYR B CD1 1 
ATOM   6011  C CD2 . TYR B 1 358 ? 11.058  -19.923 -40.278 1.00 75.57  ? 358 TYR B CD2 1 
ATOM   6012  C CE1 . TYR B 1 358 ? 12.131  -19.739 -42.817 1.00 77.26  ? 358 TYR B CE1 1 
ATOM   6013  C CE2 . TYR B 1 358 ? 12.084  -19.025 -40.528 1.00 81.94  ? 358 TYR B CE2 1 
ATOM   6014  C CZ  . TYR B 1 358 ? 12.620  -18.928 -41.801 1.00 83.13  ? 358 TYR B CZ  1 
ATOM   6015  O OH  . TYR B 1 358 ? 13.637  -18.053 -42.037 1.00 75.67  ? 358 TYR B OH  1 
ATOM   6016  N N   . GLU B 1 359 ? 12.231  -23.541 -40.916 1.00 81.08  ? 359 GLU B N   1 
ATOM   6017  C CA  . GLU B 1 359 ? 13.475  -23.827 -40.213 1.00 81.01  ? 359 GLU B CA  1 
ATOM   6018  C C   . GLU B 1 359 ? 14.437  -22.674 -40.460 1.00 82.22  ? 359 GLU B C   1 
ATOM   6019  O O   . GLU B 1 359 ? 14.727  -22.348 -41.598 1.00 99.62  ? 359 GLU B O   1 
ATOM   6020  C CB  . GLU B 1 359 ? 14.093  -25.142 -40.700 1.00 81.07  ? 359 GLU B CB  1 
ATOM   6021  C CG  . GLU B 1 359 ? 13.220  -26.370 -40.439 1.00 84.98  ? 359 GLU B CG  1 
ATOM   6022  C CD  . GLU B 1 359 ? 13.697  -27.257 -39.310 1.00 82.57  ? 359 GLU B CD  1 
ATOM   6023  O OE1 . GLU B 1 359 ? 13.555  -28.491 -39.422 1.00 84.17  ? 359 GLU B OE1 1 
ATOM   6024  O OE2 . GLU B 1 359 ? 14.244  -26.719 -38.344 1.00 88.50  ? 359 GLU B OE2 1 
ATOM   6025  N N   . GLY B 1 360 ? 14.898  -22.045 -39.382 1.00 85.21  ? 360 GLY B N   1 
ATOM   6026  C CA  . GLY B 1 360 ? 15.842  -20.945 -39.478 1.00 77.40  ? 360 GLY B CA  1 
ATOM   6027  C C   . GLY B 1 360 ? 17.262  -21.411 -39.175 1.00 75.12  ? 360 GLY B C   1 
ATOM   6028  O O   . GLY B 1 360 ? 17.467  -22.433 -38.511 1.00 73.96  ? 360 GLY B O   1 
ATOM   6029  N N   . GLY B 1 361 ? 18.238  -20.659 -39.669 1.00 76.21  ? 361 GLY B N   1 
ATOM   6030  C CA  . GLY B 1 361 ? 19.634  -20.963 -39.400 1.00 91.27  ? 361 GLY B CA  1 
ATOM   6031  C C   . GLY B 1 361 ? 20.042  -20.487 -38.007 1.00 88.37  ? 361 GLY B C   1 
ATOM   6032  O O   . GLY B 1 361 ? 19.652  -19.409 -37.589 1.00 104.22 ? 361 GLY B O   1 
ATOM   6033  N N   . VAL B 1 362 ? 20.841  -21.299 -37.307 1.00 81.22  ? 362 VAL B N   1 
ATOM   6034  C CA  . VAL B 1 362 ? 21.526  -20.845 -36.104 1.00 84.08  ? 362 VAL B CA  1 
ATOM   6035  C C   . VAL B 1 362 ? 22.909  -20.306 -36.492 1.00 87.31  ? 362 VAL B C   1 
ATOM   6036  O O   . VAL B 1 362 ? 23.715  -21.024 -37.079 1.00 92.37  ? 362 VAL B O   1 
ATOM   6037  C CB  . VAL B 1 362 ? 21.630  -21.962 -35.049 1.00 90.62  ? 362 VAL B CB  1 
ATOM   6038  C CG1 . VAL B 1 362 ? 22.557  -23.095 -35.489 1.00 91.89  ? 362 VAL B CG1 1 
ATOM   6039  C CG2 . VAL B 1 362 ? 22.050  -21.413 -33.685 1.00 94.14  ? 362 VAL B CG2 1 
ATOM   6040  N N   . ASP B 1 363 ? 23.167  -19.027 -36.148 1.00 82.97  ? 363 ASP B N   1 
ATOM   6041  C CA  . ASP B 1 363 ? 24.434  -18.370 -36.460 1.00 78.35  ? 363 ASP B CA  1 
ATOM   6042  C C   . ASP B 1 363 ? 25.043  -17.806 -35.176 1.00 73.34  ? 363 ASP B C   1 
ATOM   6043  O O   . ASP B 1 363 ? 24.744  -16.676 -34.778 1.00 63.14  ? 363 ASP B O   1 
ATOM   6044  C CB  . ASP B 1 363 ? 24.255  -17.279 -37.506 1.00 81.20  ? 363 ASP B CB  1 
ATOM   6045  C CG  . ASP B 1 363 ? 25.536  -16.569 -37.920 1.00 78.45  ? 363 ASP B CG  1 
ATOM   6046  O OD1 . ASP B 1 363 ? 26.611  -17.149 -37.710 1.00 80.34  ? 363 ASP B OD1 1 
ATOM   6047  O OD2 . ASP B 1 363 ? 25.446  -15.434 -38.424 1.00 71.88  ? 363 ASP B OD2 1 
ATOM   6048  N N   . GLY B 1 364 ? 25.922  -18.595 -34.550 1.00 69.96  ? 364 GLY B N   1 
ATOM   6049  C CA  . GLY B 1 364 ? 26.401  -18.289 -33.218 1.00 70.12  ? 364 GLY B CA  1 
ATOM   6050  C C   . GLY B 1 364 ? 25.241  -18.265 -32.227 1.00 70.21  ? 364 GLY B C   1 
ATOM   6051  O O   . GLY B 1 364 ? 24.453  -19.195 -32.177 1.00 75.60  ? 364 GLY B O   1 
ATOM   6052  N N   . GLN B 1 365 ? 25.108  -17.166 -31.493 1.00 65.42  ? 365 GLN B N   1 
ATOM   6053  C CA  . GLN B 1 365 ? 24.015  -17.015 -30.548 1.00 71.73  ? 365 GLN B CA  1 
ATOM   6054  C C   . GLN B 1 365 ? 22.714  -16.629 -31.281 1.00 72.01  ? 365 GLN B C   1 
ATOM   6055  O O   . GLN B 1 365 ? 21.624  -16.813 -30.739 1.00 65.44  ? 365 GLN B O   1 
ATOM   6056  C CB  . GLN B 1 365 ? 24.380  -15.984 -29.479 1.00 74.51  ? 365 GLN B CB  1 
ATOM   6057  C CG  . GLN B 1 365 ? 25.428  -16.468 -28.471 1.00 62.86  ? 365 GLN B CG  1 
ATOM   6058  C CD  . GLN B 1 365 ? 24.957  -17.639 -27.639 1.00 62.91  ? 365 GLN B CD  1 
ATOM   6059  O OE1 . GLN B 1 365 ? 25.613  -18.677 -27.565 1.00 59.45  ? 365 GLN B OE1 1 
ATOM   6060  N NE2 . GLN B 1 365 ? 23.808  -17.479 -26.994 1.00 71.61  ? 365 GLN B NE2 1 
ATOM   6061  N N   . LEU B 1 366 ? 22.833  -16.095 -32.514 1.00 72.55  ? 366 LEU B N   1 
ATOM   6062  C CA  . LEU B 1 366 ? 21.657  -15.719 -33.308 1.00 71.25  ? 366 LEU B CA  1 
ATOM   6063  C C   . LEU B 1 366 ? 20.901  -16.980 -33.734 1.00 69.09  ? 366 LEU B C   1 
ATOM   6064  O O   . LEU B 1 366 ? 21.391  -17.736 -34.558 1.00 86.27  ? 366 LEU B O   1 
ATOM   6065  C CB  . LEU B 1 366 ? 22.062  -14.884 -34.524 1.00 67.61  ? 366 LEU B CB  1 
ATOM   6066  C CG  . LEU B 1 366 ? 22.293  -13.385 -34.275 1.00 73.93  ? 366 LEU B CG  1 
ATOM   6067  C CD1 . LEU B 1 366 ? 22.327  -12.596 -35.595 1.00 70.00  ? 366 LEU B CD1 1 
ATOM   6068  C CD2 . LEU B 1 366 ? 21.232  -12.809 -33.356 1.00 79.25  ? 366 LEU B CD2 1 
ATOM   6069  N N   . LEU B 1 367 ? 19.702  -17.194 -33.147 1.00 66.02  ? 367 LEU B N   1 
ATOM   6070  C CA  . LEU B 1 367 ? 18.851  -18.341 -33.480 1.00 65.45  ? 367 LEU B CA  1 
ATOM   6071  C C   . LEU B 1 367 ? 17.596  -17.836 -34.162 1.00 61.68  ? 367 LEU B C   1 
ATOM   6072  O O   . LEU B 1 367 ? 16.822  -17.108 -33.558 1.00 63.40  ? 367 LEU B O   1 
ATOM   6073  C CB  . LEU B 1 367 ? 18.497  -19.154 -32.235 1.00 66.54  ? 367 LEU B CB  1 
ATOM   6074  C CG  . LEU B 1 367 ? 17.570  -20.365 -32.453 1.00 71.59  ? 367 LEU B CG  1 
ATOM   6075  C CD1 . LEU B 1 367 ? 18.269  -21.481 -33.222 1.00 73.40  ? 367 LEU B CD1 1 
ATOM   6076  C CD2 . LEU B 1 367 ? 17.041  -20.902 -31.135 1.00 72.51  ? 367 LEU B CD2 1 
ATOM   6077  N N   . ALA B 1 368 ? 17.415  -18.229 -35.439 1.00 68.49  ? 368 ALA B N   1 
ATOM   6078  C CA  . ALA B 1 368 ? 16.302  -17.752 -36.257 1.00 60.58  ? 368 ALA B CA  1 
ATOM   6079  C C   . ALA B 1 368 ? 15.030  -18.466 -35.840 1.00 49.46  ? 368 ALA B C   1 
ATOM   6080  O O   . ALA B 1 368 ? 15.089  -19.463 -35.134 1.00 52.24  ? 368 ALA B O   1 
ATOM   6081  C CB  . ALA B 1 368 ? 16.603  -17.967 -37.712 1.00 60.36  ? 368 ALA B CB  1 
ATOM   6082  N N   . PRO B 1 369 ? 13.840  -17.948 -36.206 1.00 50.32  ? 369 PRO B N   1 
ATOM   6083  C CA  . PRO B 1 369 ? 12.583  -18.589 -35.835 1.00 54.45  ? 369 PRO B CA  1 
ATOM   6084  C C   . PRO B 1 369 ? 12.471  -20.008 -36.367 1.00 58.98  ? 369 PRO B C   1 
ATOM   6085  O O   . PRO B 1 369 ? 12.928  -20.291 -37.464 1.00 71.72  ? 369 PRO B O   1 
ATOM   6086  C CB  . PRO B 1 369 ? 11.527  -17.646 -36.460 1.00 50.32  ? 369 PRO B CB  1 
ATOM   6087  C CG  . PRO B 1 369 ? 12.217  -16.307 -36.502 1.00 50.75  ? 369 PRO B CG  1 
ATOM   6088  C CD  . PRO B 1 369 ? 13.636  -16.664 -36.888 1.00 53.49  ? 369 PRO B CD  1 
ATOM   6089  N N   . HIS B 1 370 ? 11.865  -20.891 -35.565 1.00 56.93  ? 370 HIS B N   1 
ATOM   6090  C CA  . HIS B 1 370 ? 11.509  -22.224 -36.007 1.00 59.76  ? 370 HIS B CA  1 
ATOM   6091  C C   . HIS B 1 370 ? 10.037  -22.464 -35.703 1.00 64.31  ? 370 HIS B C   1 
ATOM   6092  O O   . HIS B 1 370 ? 9.607   -22.297 -34.565 1.00 63.16  ? 370 HIS B O   1 
ATOM   6093  C CB  . HIS B 1 370 ? 12.376  -23.281 -35.326 1.00 58.74  ? 370 HIS B CB  1 
ATOM   6094  C CG  . HIS B 1 370 ? 13.814  -23.208 -35.689 1.00 61.12  ? 370 HIS B CG  1 
ATOM   6095  N ND1 . HIS B 1 370 ? 14.499  -22.020 -35.801 1.00 60.63  ? 370 HIS B ND1 1 
ATOM   6096  C CD2 . HIS B 1 370 ? 14.711  -24.182 -35.942 1.00 63.72  ? 370 HIS B CD2 1 
ATOM   6097  C CE1 . HIS B 1 370 ? 15.759  -22.270 -36.140 1.00 64.67  ? 370 HIS B CE1 1 
ATOM   6098  N NE2 . HIS B 1 370 ? 15.907  -23.575 -36.243 1.00 63.90  ? 370 HIS B NE2 1 
ATOM   6099  N N   . VAL B 1 371 ? 9.279   -22.861 -36.745 1.00 64.87  ? 371 VAL B N   1 
ATOM   6100  C CA  . VAL B 1 371 ? 7.852   -23.099 -36.631 1.00 54.75  ? 371 VAL B CA  1 
ATOM   6101  C C   . VAL B 1 371 ? 7.569   -24.535 -37.036 1.00 54.01  ? 371 VAL B C   1 
ATOM   6102  O O   . VAL B 1 371 ? 7.996   -24.973 -38.077 1.00 53.68  ? 371 VAL B O   1 
ATOM   6103  C CB  . VAL B 1 371 ? 7.044   -22.116 -37.494 1.00 52.93  ? 371 VAL B CB  1 
ATOM   6104  C CG1 . VAL B 1 371 ? 5.546   -22.165 -37.154 1.00 51.35  ? 371 VAL B CG1 1 
ATOM   6105  C CG2 . VAL B 1 371 ? 7.581   -20.690 -37.385 1.00 50.59  ? 371 VAL B CG2 1 
ATOM   6106  N N   . PHE B 1 372 ? 6.843   -25.250 -36.187 1.00 59.31  ? 372 PHE B N   1 
ATOM   6107  C CA  . PHE B 1 372 ? 6.462   -26.621 -36.450 1.00 56.71  ? 372 PHE B CA  1 
ATOM   6108  C C   . PHE B 1 372 ? 4.935   -26.710 -36.512 1.00 68.09  ? 372 PHE B C   1 
ATOM   6109  O O   . PHE B 1 372 ? 4.233   -25.863 -35.941 1.00 64.15  ? 372 PHE B O   1 
ATOM   6110  C CB  . PHE B 1 372 ? 7.031   -27.533 -35.367 1.00 59.08  ? 372 PHE B CB  1 
ATOM   6111  C CG  . PHE B 1 372 ? 8.494   -27.887 -35.544 1.00 69.05  ? 372 PHE B CG  1 
ATOM   6112  C CD1 . PHE B 1 372 ? 9.500   -27.054 -35.046 1.00 73.27  ? 372 PHE B CD1 1 
ATOM   6113  C CD2 . PHE B 1 372 ? 8.871   -29.064 -36.197 1.00 79.66  ? 372 PHE B CD2 1 
ATOM   6114  C CE1 . PHE B 1 372 ? 10.843  -27.383 -35.209 1.00 76.17  ? 372 PHE B CE1 1 
ATOM   6115  C CE2 . PHE B 1 372 ? 10.215  -29.386 -36.366 1.00 77.03  ? 372 PHE B CE2 1 
ATOM   6116  C CZ  . PHE B 1 372 ? 11.198  -28.550 -35.863 1.00 78.42  ? 372 PHE B CZ  1 
ATOM   6117  N N   . GLY B 1 373 ? 4.432   -27.763 -37.201 1.00 68.71  ? 373 GLY B N   1 
ATOM   6118  C CA  . GLY B 1 373 ? 3.007   -27.946 -37.431 1.00 57.84  ? 373 GLY B CA  1 
ATOM   6119  C C   . GLY B 1 373 ? 2.548   -29.362 -37.052 1.00 65.25  ? 373 GLY B C   1 
ATOM   6120  O O   . GLY B 1 373 ? 3.374   -30.247 -36.756 1.00 65.70  ? 373 GLY B O   1 
ATOM   6121  N N   . GLU B 1 374 ? 1.209   -29.557 -37.078 1.00 64.53  ? 374 GLU B N   1 
ATOM   6122  C CA  . GLU B 1 374 ? 0.560   -30.844 -36.804 1.00 64.72  ? 374 GLU B CA  1 
ATOM   6123  C C   . GLU B 1 374 ? 0.982   -31.372 -35.431 1.00 59.14  ? 374 GLU B C   1 
ATOM   6124  O O   . GLU B 1 374 ? 1.103   -32.578 -35.246 1.00 59.78  ? 374 GLU B O   1 
ATOM   6125  C CB  . GLU B 1 374 ? 0.865   -31.895 -37.884 1.00 72.86  ? 374 GLU B CB  1 
ATOM   6126  C CG  . GLU B 1 374 ? 0.835   -31.354 -39.317 1.00 74.25  ? 374 GLU B CG  1 
ATOM   6127  C CD  . GLU B 1 374 ? -0.473  -30.698 -39.723 1.00 80.56  ? 374 GLU B CD  1 
ATOM   6128  O OE1 . GLU B 1 374 ? -1.538  -31.365 -39.587 1.00 73.89  ? 374 GLU B OE1 1 
ATOM   6129  O OE2 . GLU B 1 374 ? -0.432  -29.516 -40.167 1.00 85.77  ? 374 GLU B OE2 1 
ATOM   6130  N N   . VAL B 1 375 ? 1.123   -30.460 -34.458 1.00 60.69  ? 375 VAL B N   1 
ATOM   6131  C CA  . VAL B 1 375 ? 1.627   -30.808 -33.133 1.00 56.76  ? 375 VAL B CA  1 
ATOM   6132  C C   . VAL B 1 375 ? 0.503   -31.443 -32.318 1.00 52.14  ? 375 VAL B C   1 
ATOM   6133  O O   . VAL B 1 375 ? -0.667  -31.137 -32.533 1.00 53.45  ? 375 VAL B O   1 
ATOM   6134  C CB  . VAL B 1 375 ? 2.205   -29.561 -32.439 1.00 58.69  ? 375 VAL B CB  1 
ATOM   6135  C CG1 . VAL B 1 375 ? 2.667   -29.853 -31.015 1.00 53.69  ? 375 VAL B CG1 1 
ATOM   6136  C CG2 . VAL B 1 375 ? 3.339   -28.928 -33.260 1.00 61.68  ? 375 VAL B CG2 1 
ATOM   6137  N N   . THR B 1 376 ? 0.877   -32.334 -31.382 1.00 57.61  ? 376 THR B N   1 
ATOM   6138  C CA  . THR B 1 376 ? -0.088  -33.000 -30.504 1.00 65.26  ? 376 THR B CA  1 
ATOM   6139  C C   . THR B 1 376 ? 0.228   -32.659 -29.043 1.00 66.62  ? 376 THR B C   1 
ATOM   6140  O O   . THR B 1 376 ? 1.321   -32.201 -28.725 1.00 65.68  ? 376 THR B O   1 
ATOM   6141  C CB  . THR B 1 376 ? -0.059  -34.519 -30.741 1.00 76.37  ? 376 THR B CB  1 
ATOM   6142  O OG1 . THR B 1 376 ? 0.949   -35.088 -29.903 1.00 66.41  ? 376 THR B OG1 1 
ATOM   6143  C CG2 . THR B 1 376 ? 0.234   -34.877 -32.185 1.00 85.09  ? 376 THR B CG2 1 
ATOM   6144  N N   . ALA B 1 377 ? -0.731  -32.946 -28.155 1.00 72.02  ? 377 ALA B N   1 
ATOM   6145  C CA  . ALA B 1 377 ? -0.619  -32.587 -26.746 1.00 72.12  ? 377 ALA B CA  1 
ATOM   6146  C C   . ALA B 1 377 ? 0.529   -33.356 -26.082 1.00 71.61  ? 377 ALA B C   1 
ATOM   6147  O O   . ALA B 1 377 ? 1.167   -32.843 -25.170 1.00 71.55  ? 377 ALA B O   1 
ATOM   6148  C CB  . ALA B 1 377 ? -1.935  -32.839 -26.041 1.00 71.59  ? 377 ALA B CB  1 
ATOM   6149  N N   . THR B 1 378 ? 0.798   -34.579 -26.567 1.00 73.17  ? 378 THR B N   1 
ATOM   6150  C CA  . THR B 1 378 ? 1.783   -35.457 -25.940 1.00 74.83  ? 378 THR B CA  1 
ATOM   6151  C C   . THR B 1 378 ? 3.202   -35.023 -26.319 1.00 68.73  ? 378 THR B C   1 
ATOM   6152  O O   . THR B 1 378 ? 4.157   -35.424 -25.659 1.00 74.26  ? 378 THR B O   1 
ATOM   6153  C CB  . THR B 1 378 ? 1.539   -36.923 -26.327 1.00 81.78  ? 378 THR B CB  1 
ATOM   6154  O OG1 . THR B 1 378 ? 1.075   -36.919 -27.675 1.00 85.30  ? 378 THR B OG1 1 
ATOM   6155  C CG2 . THR B 1 378 ? 0.530   -37.606 -25.417 1.00 79.62  ? 378 THR B CG2 1 
ATOM   6156  N N   . MET B 1 379 ? 3.337   -34.230 -27.390 1.00 58.54  ? 379 MET B N   1 
ATOM   6157  C CA  . MET B 1 379 ? 4.651   -33.806 -27.859 1.00 59.33  ? 379 MET B CA  1 
ATOM   6158  C C   . MET B 1 379 ? 5.276   -32.844 -26.847 1.00 65.29  ? 379 MET B C   1 
ATOM   6159  O O   . MET B 1 379 ? 4.568   -32.111 -26.159 1.00 71.90  ? 379 MET B O   1 
ATOM   6160  C CB  . MET B 1 379 ? 4.556   -33.131 -29.227 1.00 60.92  ? 379 MET B CB  1 
ATOM   6161  C CG  . MET B 1 379 ? 4.065   -34.037 -30.310 1.00 59.87  ? 379 MET B CG  1 
ATOM   6162  S SD  . MET B 1 379 ? 4.095   -33.244 -31.921 1.00 73.82  ? 379 MET B SD  1 
ATOM   6163  C CE  . MET B 1 379 ? 3.959   -34.660 -33.025 1.00 72.60  ? 379 MET B CE  1 
ATOM   6164  N N   . GLU B 1 380 ? 6.612   -32.863 -26.763 1.00 71.32  ? 380 GLU B N   1 
ATOM   6165  C CA  . GLU B 1 380 ? 7.337   -32.099 -25.752 1.00 73.34  ? 380 GLU B CA  1 
ATOM   6166  C C   . GLU B 1 380 ? 7.203   -30.593 -26.025 1.00 68.09  ? 380 GLU B C   1 
ATOM   6167  O O   . GLU B 1 380 ? 7.137   -29.789 -25.084 1.00 60.38  ? 380 GLU B O   1 
ATOM   6168  C CB  . GLU B 1 380 ? 8.802   -32.531 -25.701 1.00 77.96  ? 380 GLU B CB  1 
ATOM   6169  C CG  . GLU B 1 380 ? 9.540   -32.036 -24.454 1.00 89.80  ? 380 GLU B CG  1 
ATOM   6170  C CD  . GLU B 1 380 ? 10.331  -30.734 -24.624 1.00 100.32 ? 380 GLU B CD  1 
ATOM   6171  O OE1 . GLU B 1 380 ? 11.094  -30.405 -23.701 1.00 104.48 ? 380 GLU B OE1 1 
ATOM   6172  O OE2 . GLU B 1 380 ? 10.199  -30.063 -25.683 1.00 102.61 ? 380 GLU B OE2 1 
ATOM   6173  N N   . ILE B 1 381 ? 7.170   -30.220 -27.315 1.00 66.87  ? 381 ILE B N   1 
ATOM   6174  C CA  . ILE B 1 381 ? 7.117   -28.813 -27.708 1.00 66.32  ? 381 ILE B CA  1 
ATOM   6175  C C   . ILE B 1 381 ? 5.820   -28.172 -27.174 1.00 69.17  ? 381 ILE B C   1 
ATOM   6176  O O   . ILE B 1 381 ? 5.794   -26.979 -26.869 1.00 79.58  ? 381 ILE B O   1 
ATOM   6177  C CB  . ILE B 1 381 ? 7.242   -28.659 -29.231 1.00 65.95  ? 381 ILE B CB  1 
ATOM   6178  C CG1 . ILE B 1 381 ? 7.449   -27.207 -29.615 1.00 73.30  ? 381 ILE B CG1 1 
ATOM   6179  C CG2 . ILE B 1 381 ? 6.035   -29.269 -29.947 1.00 69.10  ? 381 ILE B CG2 1 
ATOM   6180  C CD1 . ILE B 1 381 ? 7.655   -26.971 -31.103 1.00 71.50  ? 381 ILE B CD1 1 
ATOM   6181  N N   . ALA B 1 382 ? 4.762   -28.977 -27.040 1.00 62.86  ? 382 ALA B N   1 
ATOM   6182  C CA  . ALA B 1 382 ? 3.486   -28.482 -26.545 1.00 68.67  ? 382 ALA B CA  1 
ATOM   6183  C C   . ALA B 1 382 ? 3.503   -28.377 -25.019 1.00 70.24  ? 382 ALA B C   1 
ATOM   6184  O O   . ALA B 1 382 ? 3.025   -27.393 -24.471 1.00 76.21  ? 382 ALA B O   1 
ATOM   6185  C CB  . ALA B 1 382 ? 2.362   -29.367 -27.022 1.00 71.75  ? 382 ALA B CB  1 
ATOM   6186  N N   . ARG B 1 383 ? 4.028   -29.405 -24.330 1.00 71.33  ? 383 ARG B N   1 
ATOM   6187  C CA  . ARG B 1 383 ? 3.789   -29.537 -22.887 1.00 75.66  ? 383 ARG B CA  1 
ATOM   6188  C C   . ARG B 1 383 ? 4.852   -28.750 -22.081 1.00 64.70  ? 383 ARG B C   1 
ATOM   6189  O O   . ARG B 1 383 ? 4.535   -28.214 -21.021 1.00 60.54  ? 383 ARG B O   1 
ATOM   6190  C CB  . ARG B 1 383 ? 3.622   -31.012 -22.451 1.00 78.17  ? 383 ARG B CB  1 
ATOM   6191  N N   . ASP B 1 384 ? 6.104   -28.674 -22.580 1.00 63.38  ? 384 ASP B N   1 
ATOM   6192  C CA  . ASP B 1 384 ? 7.195   -28.058 -21.806 1.00 69.93  ? 384 ASP B CA  1 
ATOM   6193  C C   . ASP B 1 384 ? 7.369   -26.582 -22.203 1.00 72.96  ? 384 ASP B C   1 
ATOM   6194  O O   . ASP B 1 384 ? 7.050   -26.186 -23.324 1.00 68.27  ? 384 ASP B O   1 
ATOM   6195  C CB  . ASP B 1 384 ? 8.497   -28.833 -21.935 1.00 74.96  ? 384 ASP B CB  1 
ATOM   6196  C CG  . ASP B 1 384 ? 8.766   -29.865 -20.838 1.00 82.28  ? 384 ASP B CG  1 
ATOM   6197  O OD1 . ASP B 1 384 ? 9.890   -30.400 -20.802 1.00 85.67  ? 384 ASP B OD1 1 
ATOM   6198  O OD2 . ASP B 1 384 ? 7.843   -30.131 -20.023 1.00 73.19  ? 384 ASP B OD2 1 
ATOM   6199  N N   . GLU B 1 385 ? 7.912   -25.786 -21.269 1.00 63.36  ? 385 GLU B N   1 
ATOM   6200  C CA  . GLU B 1 385 ? 8.055   -24.340 -21.465 1.00 70.66  ? 385 GLU B CA  1 
ATOM   6201  C C   . GLU B 1 385 ? 9.233   -24.060 -22.396 1.00 66.15  ? 385 GLU B C   1 
ATOM   6202  O O   . GLU B 1 385 ? 10.270  -24.713 -22.301 1.00 64.28  ? 385 GLU B O   1 
ATOM   6203  C CB  . GLU B 1 385 ? 8.232   -23.568 -20.147 1.00 73.23  ? 385 GLU B CB  1 
ATOM   6204  C CG  . GLU B 1 385 ? 8.972   -24.350 -19.067 1.00 85.18  ? 385 GLU B CG  1 
ATOM   6205  C CD  . GLU B 1 385 ? 9.304   -23.546 -17.829 1.00 90.88  ? 385 GLU B CD  1 
ATOM   6206  O OE1 . GLU B 1 385 ? 8.397   -22.894 -17.305 1.00 92.16  ? 385 GLU B OE1 1 
ATOM   6207  O OE2 . GLU B 1 385 ? 10.464  -23.593 -17.375 1.00 99.48  ? 385 GLU B OE2 1 
ATOM   6208  N N   . ILE B 1 386 ? 9.043   -23.083 -23.308 1.00 63.16  ? 386 ILE B N   1 
ATOM   6209  C CA  . ILE B 1 386 ? 10.064  -22.695 -24.273 1.00 61.73  ? 386 ILE B CA  1 
ATOM   6210  C C   . ILE B 1 386 ? 10.467  -21.257 -24.001 1.00 63.78  ? 386 ILE B C   1 
ATOM   6211  O O   . ILE B 1 386 ? 9.617   -20.386 -23.906 1.00 68.88  ? 386 ILE B O   1 
ATOM   6212  C CB  . ILE B 1 386 ? 9.568   -22.840 -25.723 1.00 65.81  ? 386 ILE B CB  1 
ATOM   6213  C CG1 . ILE B 1 386 ? 8.682   -24.093 -25.930 1.00 73.08  ? 386 ILE B CG1 1 
ATOM   6214  C CG2 . ILE B 1 386 ? 10.751  -22.811 -26.690 1.00 69.76  ? 386 ILE B CG2 1 
ATOM   6215  C CD1 . ILE B 1 386 ? 9.311   -25.398 -25.450 1.00 80.50  ? 386 ILE B CD1 1 
ATOM   6216  N N   . PHE B 1 387 ? 11.765  -21.004 -23.944 1.00 64.99  ? 387 PHE B N   1 
ATOM   6217  C CA  . PHE B 1 387 ? 12.258  -19.654 -23.761 1.00 68.74  ? 387 PHE B CA  1 
ATOM   6218  C C   . PHE B 1 387 ? 13.088  -19.261 -24.976 1.00 70.72  ? 387 PHE B C   1 
ATOM   6219  O O   . PHE B 1 387 ? 14.275  -18.959 -24.858 1.00 79.18  ? 387 PHE B O   1 
ATOM   6220  C CB  . PHE B 1 387 ? 13.059  -19.557 -22.458 1.00 82.02  ? 387 PHE B CB  1 
ATOM   6221  C CG  . PHE B 1 387 ? 12.231  -19.683 -21.185 1.00 95.32  ? 387 PHE B CG  1 
ATOM   6222  C CD1 . PHE B 1 387 ? 12.376  -20.782 -20.343 1.00 106.50 ? 387 PHE B CD1 1 
ATOM   6223  C CD2 . PHE B 1 387 ? 11.284  -18.720 -20.845 1.00 97.50  ? 387 PHE B CD2 1 
ATOM   6224  C CE1 . PHE B 1 387 ? 11.612  -20.895 -19.184 1.00 104.90 ? 387 PHE B CE1 1 
ATOM   6225  C CE2 . PHE B 1 387 ? 10.517  -18.849 -19.688 1.00 91.17  ? 387 PHE B CE2 1 
ATOM   6226  C CZ  . PHE B 1 387 ? 10.683  -19.929 -18.866 1.00 90.52  ? 387 PHE B CZ  1 
ATOM   6227  N N   . GLY B 1 388 ? 12.459  -19.282 -26.147 1.00 70.33  ? 388 GLY B N   1 
ATOM   6228  C CA  . GLY B 1 388 ? 13.141  -18.914 -27.375 1.00 66.58  ? 388 GLY B CA  1 
ATOM   6229  C C   . GLY B 1 388 ? 12.192  -18.903 -28.570 1.00 64.95  ? 388 GLY B C   1 
ATOM   6230  O O   . GLY B 1 388 ? 11.003  -19.156 -28.429 1.00 63.80  ? 388 GLY B O   1 
ATOM   6231  N N   . PRO B 1 389 ? 12.710  -18.640 -29.787 1.00 63.09  ? 389 PRO B N   1 
ATOM   6232  C CA  . PRO B 1 389 ? 11.874  -18.515 -30.983 1.00 58.99  ? 389 PRO B CA  1 
ATOM   6233  C C   . PRO B 1 389 ? 11.524  -19.860 -31.610 1.00 53.73  ? 389 PRO B C   1 
ATOM   6234  O O   . PRO B 1 389 ? 11.770  -20.079 -32.787 1.00 53.63  ? 389 PRO B O   1 
ATOM   6235  C CB  . PRO B 1 389 ? 12.770  -17.663 -31.896 1.00 63.90  ? 389 PRO B CB  1 
ATOM   6236  C CG  . PRO B 1 389 ? 14.179  -18.140 -31.565 1.00 69.48  ? 389 PRO B CG  1 
ATOM   6237  C CD  . PRO B 1 389 ? 14.141  -18.476 -30.071 1.00 68.30  ? 389 PRO B CD  1 
ATOM   6238  N N   . LEU B 1 390 ? 10.945  -20.744 -30.799 1.00 53.06  ? 390 LEU B N   1 
ATOM   6239  C CA  . LEU B 1 390 ? 10.459  -22.027 -31.257 1.00 54.22  ? 390 LEU B CA  1 
ATOM   6240  C C   . LEU B 1 390 ? 8.969   -22.138 -30.912 1.00 51.17  ? 390 LEU B C   1 
ATOM   6241  O O   . LEU B 1 390 ? 8.590   -21.963 -29.764 1.00 59.29  ? 390 LEU B O   1 
ATOM   6242  C CB  . LEU B 1 390 ? 11.285  -23.136 -30.603 1.00 54.18  ? 390 LEU B CB  1 
ATOM   6243  C CG  . LEU B 1 390 ? 10.712  -24.552 -30.727 1.00 64.39  ? 390 LEU B CG  1 
ATOM   6244  C CD1 . LEU B 1 390 ? 10.883  -25.072 -32.164 1.00 67.04  ? 390 LEU B CD1 1 
ATOM   6245  C CD2 . LEU B 1 390 ? 11.326  -25.521 -29.713 1.00 62.59  ? 390 LEU B CD2 1 
ATOM   6246  N N   . VAL B 1 391 ? 8.139   -22.441 -31.925 1.00 49.31  ? 391 VAL B N   1 
ATOM   6247  C CA  . VAL B 1 391 ? 6.690   -22.448 -31.774 1.00 54.56  ? 391 VAL B CA  1 
ATOM   6248  C C   . VAL B 1 391 ? 6.120   -23.717 -32.404 1.00 55.34  ? 391 VAL B C   1 
ATOM   6249  O O   . VAL B 1 391 ? 6.560   -24.140 -33.476 1.00 50.20  ? 391 VAL B O   1 
ATOM   6250  C CB  . VAL B 1 391 ? 6.020   -21.224 -32.413 1.00 60.88  ? 391 VAL B CB  1 
ATOM   6251  C CG1 . VAL B 1 391 ? 4.738   -20.856 -31.680 1.00 63.94  ? 391 VAL B CG1 1 
ATOM   6252  C CG2 . VAL B 1 391 ? 6.962   -20.035 -32.510 1.00 67.20  ? 391 VAL B CG2 1 
ATOM   6253  N N   . GLY B 1 392 ? 5.061   -24.239 -31.782 1.00 52.01  ? 392 GLY B N   1 
ATOM   6254  C CA  . GLY B 1 392 ? 4.297   -25.345 -32.328 1.00 53.79  ? 392 GLY B CA  1 
ATOM   6255  C C   . GLY B 1 392 ? 2.857   -24.919 -32.646 1.00 60.30  ? 392 GLY B C   1 
ATOM   6256  O O   . GLY B 1 392 ? 2.256   -24.145 -31.901 1.00 54.74  ? 392 GLY B O   1 
ATOM   6257  N N   . LEU B 1 393 ? 2.332   -25.404 -33.791 1.00 64.34  ? 393 LEU B N   1 
ATOM   6258  C CA  . LEU B 1 393 ? 0.962   -25.118 -34.216 1.00 60.82  ? 393 LEU B CA  1 
ATOM   6259  C C   . LEU B 1 393 ? 0.132   -26.400 -34.094 1.00 60.43  ? 393 LEU B C   1 
ATOM   6260  O O   . LEU B 1 393 ? 0.549   -27.453 -34.571 1.00 64.81  ? 393 LEU B O   1 
ATOM   6261  C CB  . LEU B 1 393 ? 0.958   -24.572 -35.648 1.00 55.28  ? 393 LEU B CB  1 
ATOM   6262  C CG  . LEU B 1 393 ? 1.020   -23.048 -35.798 1.00 61.82  ? 393 LEU B CG  1 
ATOM   6263  C CD1 . LEU B 1 393 ? 2.358   -22.472 -35.347 1.00 63.85  ? 393 LEU B CD1 1 
ATOM   6264  C CD2 . LEU B 1 393 ? 0.732   -22.642 -37.237 1.00 62.00  ? 393 LEU B CD2 1 
ATOM   6265  N N   . LEU B 1 394 ? -1.037  -26.298 -33.429 1.00 53.55  ? 394 LEU B N   1 
ATOM   6266  C CA  . LEU B 1 394 ? -1.874  -27.459 -33.139 1.00 52.09  ? 394 LEU B CA  1 
ATOM   6267  C C   . LEU B 1 394 ? -3.208  -27.329 -33.865 1.00 57.30  ? 394 LEU B C   1 
ATOM   6268  O O   . LEU B 1 394 ? -3.820  -26.260 -33.863 1.00 59.08  ? 394 LEU B O   1 
ATOM   6269  C CB  . LEU B 1 394 ? -2.103  -27.603 -31.642 1.00 52.54  ? 394 LEU B CB  1 
ATOM   6270  C CG  . LEU B 1 394 ? -0.994  -28.286 -30.856 1.00 52.93  ? 394 LEU B CG  1 
ATOM   6271  C CD1 . LEU B 1 394 ? 0.086   -27.287 -30.486 1.00 57.50  ? 394 LEU B CD1 1 
ATOM   6272  C CD2 . LEU B 1 394 ? -1.542  -28.971 -29.633 1.00 46.89  ? 394 LEU B CD2 1 
ATOM   6273  N N   . ARG B 1 395 ? -3.696  -28.469 -34.383 1.00 60.17  ? 395 ARG B N   1 
ATOM   6274  C CA  . ARG B 1 395 ? -4.961  -28.537 -35.092 1.00 61.01  ? 395 ARG B CA  1 
ATOM   6275  C C   . ARG B 1 395 ? -6.055  -29.031 -34.135 1.00 54.79  ? 395 ARG B C   1 
ATOM   6276  O O   . ARG B 1 395 ? -5.910  -30.080 -33.499 1.00 56.47  ? 395 ARG B O   1 
ATOM   6277  C CB  . ARG B 1 395 ? -4.785  -29.473 -36.294 1.00 67.84  ? 395 ARG B CB  1 
ATOM   6278  C CG  . ARG B 1 395 ? -5.706  -29.219 -37.480 1.00 67.38  ? 395 ARG B CG  1 
ATOM   6279  C CD  . ARG B 1 395 ? -5.476  -30.270 -38.636 1.00 64.65  ? 395 ARG B CD  1 
ATOM   6280  N NE  . ARG B 1 395 ? -4.537  -29.788 -39.665 1.00 62.32  ? 395 ARG B NE  1 
ATOM   6281  C CZ  . ARG B 1 395 ? -4.903  -29.185 -40.804 1.00 63.90  ? 395 ARG B CZ  1 
ATOM   6282  N NH1 . ARG B 1 395 ? -6.183  -28.907 -41.042 1.00 63.22  ? 395 ARG B NH1 1 
ATOM   6283  N NH2 . ARG B 1 395 ? -3.990  -28.846 -41.690 1.00 69.17  ? 395 ARG B NH2 1 
ATOM   6284  N N   . ALA B 1 396 ? -7.161  -28.283 -34.076 1.00 52.37  ? 396 ALA B N   1 
ATOM   6285  C CA  . ALA B 1 396 ? -8.290  -28.631 -33.224 1.00 62.02  ? 396 ALA B CA  1 
ATOM   6286  C C   . ALA B 1 396 ? -9.521  -28.909 -34.081 1.00 62.07  ? 396 ALA B C   1 
ATOM   6287  O O   . ALA B 1 396 ? -9.877  -28.106 -34.947 1.00 56.93  ? 396 ALA B O   1 
ATOM   6288  C CB  . ALA B 1 396 ? -8.556  -27.512 -32.238 1.00 66.80  ? 396 ALA B CB  1 
ATOM   6289  N N   . ARG B 1 397 ? -10.196 -30.025 -33.789 1.00 66.62  ? 397 ARG B N   1 
ATOM   6290  C CA  . ARG B 1 397 ? -11.313 -30.476 -34.598 1.00 69.70  ? 397 ARG B CA  1 
ATOM   6291  C C   . ARG B 1 397 ? -12.523 -29.588 -34.341 1.00 72.93  ? 397 ARG B C   1 
ATOM   6292  O O   . ARG B 1 397 ? -13.163 -29.136 -35.283 1.00 76.81  ? 397 ARG B O   1 
ATOM   6293  C CB  . ARG B 1 397 ? -11.633 -31.952 -34.371 1.00 65.07  ? 397 ARG B CB  1 
ATOM   6294  C CG  . ARG B 1 397 ? -11.647 -32.414 -32.934 1.00 72.27  ? 397 ARG B CG  1 
ATOM   6295  C CD  . ARG B 1 397 ? -11.616 -33.931 -32.890 1.00 72.92  ? 397 ARG B CD  1 
ATOM   6296  N NE  . ARG B 1 397 ? -11.877 -34.442 -31.543 1.00 74.38  ? 397 ARG B NE  1 
ATOM   6297  C CZ  . ARG B 1 397 ? -11.038 -35.187 -30.831 1.00 77.22  ? 397 ARG B CZ  1 
ATOM   6298  N NH1 . ARG B 1 397 ? -9.882  -35.575 -31.350 1.00 72.79  ? 397 ARG B NH1 1 
ATOM   6299  N NH2 . ARG B 1 397 ? -11.359 -35.539 -29.593 1.00 83.34  ? 397 ARG B NH2 1 
ATOM   6300  N N   . ASP B 1 398 ? -12.821 -29.330 -33.064 1.00 74.54  ? 398 ASP B N   1 
ATOM   6301  C CA  . ASP B 1 398 ? -13.928 -28.446 -32.705 1.00 76.65  ? 398 ASP B CA  1 
ATOM   6302  C C   . ASP B 1 398 ? -13.520 -27.595 -31.505 1.00 77.03  ? 398 ASP B C   1 
ATOM   6303  O O   . ASP B 1 398 ? -12.424 -27.760 -30.964 1.00 75.18  ? 398 ASP B O   1 
ATOM   6304  C CB  . ASP B 1 398 ? -15.200 -29.239 -32.443 1.00 71.21  ? 398 ASP B CB  1 
ATOM   6305  C CG  . ASP B 1 398 ? -15.025 -30.435 -31.527 1.00 72.96  ? 398 ASP B CG  1 
ATOM   6306  O OD1 . ASP B 1 398 ? -14.658 -30.225 -30.348 1.00 75.15  ? 398 ASP B OD1 1 
ATOM   6307  O OD2 . ASP B 1 398 ? -15.206 -31.561 -32.009 1.00 75.79  ? 398 ASP B OD2 1 
ATOM   6308  N N   . GLU B 1 399 ? -14.436 -26.711 -31.075 1.00 73.29  ? 399 GLU B N   1 
ATOM   6309  C CA  . GLU B 1 399 ? -14.202 -25.823 -29.943 1.00 62.97  ? 399 GLU B CA  1 
ATOM   6310  C C   . GLU B 1 399 ? -13.934 -26.642 -28.661 1.00 58.44  ? 399 GLU B C   1 
ATOM   6311  O O   . GLU B 1 399 ? -13.055 -26.294 -27.883 1.00 56.02  ? 399 GLU B O   1 
ATOM   6312  C CB  . GLU B 1 399 ? -15.383 -24.868 -29.788 1.00 62.28  ? 399 GLU B CB  1 
ATOM   6313  C CG  . GLU B 1 399 ? -15.265 -23.927 -28.592 1.00 63.07  ? 399 GLU B CG  1 
ATOM   6314  C CD  . GLU B 1 399 ? -16.509 -23.078 -28.347 1.00 64.61  ? 399 GLU B CD  1 
ATOM   6315  O OE1 . GLU B 1 399 ? -17.274 -22.848 -29.314 1.00 69.41  ? 399 GLU B OE1 1 
ATOM   6316  O OE2 . GLU B 1 399 ? -16.725 -22.661 -27.178 1.00 67.32  ? 399 GLU B OE2 1 
ATOM   6317  N N   . ALA B 1 400 ? -14.697 -27.722 -28.453 1.00 57.95  ? 400 ALA B N   1 
ATOM   6318  C CA  . ALA B 1 400 ? -14.526 -28.571 -27.269 1.00 56.87  ? 400 ALA B CA  1 
ATOM   6319  C C   . ALA B 1 400 ? -13.104 -29.152 -27.220 1.00 55.85  ? 400 ALA B C   1 
ATOM   6320  O O   . ALA B 1 400 ? -12.484 -29.207 -26.159 1.00 49.78  ? 400 ALA B O   1 
ATOM   6321  C CB  . ALA B 1 400 ? -15.568 -29.669 -27.262 1.00 58.10  ? 400 ALA B CB  1 
ATOM   6322  N N   . HIS B 1 401 ? -12.593 -29.573 -28.380 1.00 53.14  ? 401 HIS B N   1 
ATOM   6323  C CA  . HIS B 1 401 ? -11.248 -30.115 -28.469 1.00 53.04  ? 401 HIS B CA  1 
ATOM   6324  C C   . HIS B 1 401 ? -10.220 -29.016 -28.138 1.00 59.26  ? 401 HIS B C   1 
ATOM   6325  O O   . HIS B 1 401 ? -9.232  -29.281 -27.464 1.00 60.81  ? 401 HIS B O   1 
ATOM   6326  C CB  . HIS B 1 401 ? -11.016 -30.749 -29.847 1.00 52.37  ? 401 HIS B CB  1 
ATOM   6327  C CG  . HIS B 1 401 ? -9.735  -31.488 -29.963 1.00 51.05  ? 401 HIS B CG  1 
ATOM   6328  N ND1 . HIS B 1 401 ? -8.946  -31.444 -31.100 1.00 55.75  ? 401 HIS B ND1 1 
ATOM   6329  C CD2 . HIS B 1 401 ? -9.085  -32.274 -29.081 1.00 52.34  ? 401 HIS B CD2 1 
ATOM   6330  C CE1 . HIS B 1 401 ? -7.845  -32.166 -30.898 1.00 57.70  ? 401 HIS B CE1 1 
ATOM   6331  N NE2 . HIS B 1 401 ? -7.915  -32.695 -29.676 1.00 54.99  ? 401 HIS B NE2 1 
ATOM   6332  N N   . ALA B 1 402 ? -10.463 -27.782 -28.634 1.00 56.16  ? 402 ALA B N   1 
ATOM   6333  C CA  . ALA B 1 402 ? -9.537  -26.674 -28.433 1.00 52.07  ? 402 ALA B CA  1 
ATOM   6334  C C   . ALA B 1 402 ? -9.389  -26.377 -26.941 1.00 51.54  ? 402 ALA B C   1 
ATOM   6335  O O   . ALA B 1 402 ? -8.291  -26.071 -26.477 1.00 43.10  ? 402 ALA B O   1 
ATOM   6336  C CB  . ALA B 1 402 ? -10.006 -25.452 -29.186 1.00 53.84  ? 402 ALA B CB  1 
ATOM   6337  N N   . LEU B 1 403 ? -10.506 -26.500 -26.198 1.00 50.20  ? 403 LEU B N   1 
ATOM   6338  C CA  . LEU B 1 403 ? -10.519 -26.250 -24.767 1.00 52.48  ? 403 LEU B CA  1 
ATOM   6339  C C   . LEU B 1 403 ? -9.661  -27.296 -24.051 1.00 55.25  ? 403 LEU B C   1 
ATOM   6340  O O   . LEU B 1 403 ? -8.873  -26.953 -23.167 1.00 66.64  ? 403 LEU B O   1 
ATOM   6341  C CB  . LEU B 1 403 ? -11.952 -26.244 -24.233 1.00 54.39  ? 403 LEU B CB  1 
ATOM   6342  C CG  . LEU B 1 403 ? -12.106 -25.975 -22.725 1.00 52.79  ? 403 LEU B CG  1 
ATOM   6343  C CD1 . LEU B 1 403 ? -11.406 -24.665 -22.297 1.00 52.12  ? 403 LEU B CD1 1 
ATOM   6344  C CD2 . LEU B 1 403 ? -13.566 -25.951 -22.351 1.00 51.12  ? 403 LEU B CD2 1 
ATOM   6345  N N   . GLU B 1 404 ? -9.808  -28.567 -24.446 1.00 54.77  ? 404 GLU B N   1 
ATOM   6346  C CA  . GLU B 1 404 ? -9.023  -29.655 -23.853 1.00 58.40  ? 404 GLU B CA  1 
ATOM   6347  C C   . GLU B 1 404 ? -7.531  -29.402 -24.110 1.00 57.15  ? 404 GLU B C   1 
ATOM   6348  O O   . GLU B 1 404 ? -6.696  -29.564 -23.207 1.00 55.09  ? 404 GLU B O   1 
ATOM   6349  C CB  . GLU B 1 404 ? -9.487  -31.026 -24.385 1.00 63.15  ? 404 GLU B CB  1 
ATOM   6350  C CG  . GLU B 1 404 ? -8.372  -32.075 -24.462 1.00 74.42  ? 404 GLU B CG  1 
ATOM   6351  C CD  . GLU B 1 404 ? -8.808  -33.461 -24.962 1.00 75.22  ? 404 GLU B CD  1 
ATOM   6352  O OE1 . GLU B 1 404 ? -9.573  -34.126 -24.240 1.00 73.29  ? 404 GLU B OE1 1 
ATOM   6353  O OE2 . GLU B 1 404 ? -8.373  -33.875 -26.070 1.00 80.47  ? 404 GLU B OE2 1 
ATOM   6354  N N   . LEU B 1 405 ? -7.210  -29.016 -25.351 1.00 51.56  ? 405 LEU B N   1 
ATOM   6355  C CA  . LEU B 1 405 ? -5.838  -28.774 -25.756 1.00 52.33  ? 405 LEU B CA  1 
ATOM   6356  C C   . LEU B 1 405 ? -5.240  -27.624 -24.949 1.00 53.30  ? 405 LEU B C   1 
ATOM   6357  O O   . LEU B 1 405 ? -4.094  -27.708 -24.538 1.00 61.38  ? 405 LEU B O   1 
ATOM   6358  C CB  . LEU B 1 405 ? -5.783  -28.499 -27.260 1.00 53.48  ? 405 LEU B CB  1 
ATOM   6359  C CG  . LEU B 1 405 ? -6.061  -29.709 -28.164 1.00 55.28  ? 405 LEU B CG  1 
ATOM   6360  C CD1 . LEU B 1 405 ? -5.830  -29.350 -29.615 1.00 59.42  ? 405 LEU B CD1 1 
ATOM   6361  C CD2 . LEU B 1 405 ? -5.206  -30.926 -27.772 1.00 51.37  ? 405 LEU B CD2 1 
ATOM   6362  N N   . ALA B 1 406 ? -6.013  -26.537 -24.755 1.00 55.91  ? 406 ALA B N   1 
ATOM   6363  C CA  . ALA B 1 406 ? -5.522  -25.359 -24.034 1.00 58.68  ? 406 ALA B CA  1 
ATOM   6364  C C   . ALA B 1 406 ? -5.289  -25.707 -22.569 1.00 54.96  ? 406 ALA B C   1 
ATOM   6365  O O   . ALA B 1 406 ? -4.289  -25.316 -21.987 1.00 59.33  ? 406 ALA B O   1 
ATOM   6366  C CB  . ALA B 1 406 ? -6.496  -24.198 -24.178 1.00 56.42  ? 406 ALA B CB  1 
ATOM   6367  N N   . ASN B 1 407 ? -6.216  -26.456 -21.974 1.00 57.93  ? 407 ASN B N   1 
ATOM   6368  C CA  . ASN B 1 407 ? -6.109  -26.752 -20.518 1.00 59.85  ? 407 ASN B CA  1 
ATOM   6369  C C   . ASN B 1 407 ? -5.172  -27.943 -20.285 1.00 60.78  ? 407 ASN B C   1 
ATOM   6370  O O   . ASN B 1 407 ? -4.997  -28.336 -19.115 1.00 55.88  ? 407 ASN B O   1 
ATOM   6371  C CB  . ASN B 1 407 ? -7.491  -26.930 -19.900 1.00 63.02  ? 407 ASN B CB  1 
ATOM   6372  C CG  . ASN B 1 407 ? -8.204  -25.610 -19.740 1.00 61.69  ? 407 ASN B CG  1 
ATOM   6373  O OD1 . ASN B 1 407 ? -7.592  -24.550 -19.910 1.00 60.65  ? 407 ASN B OD1 1 
ATOM   6374  N ND2 . ASN B 1 407 ? -9.487  -25.647 -19.414 1.00 64.48  ? 407 ASN B ND2 1 
ATOM   6375  N N   . ALA B 1 408 ? -4.584  -28.482 -21.355 1.00 67.24  ? 408 ALA B N   1 
ATOM   6376  C CA  . ALA B 1 408 ? -3.655  -29.631 -21.235 1.00 68.89  ? 408 ALA B CA  1 
ATOM   6377  C C   . ALA B 1 408 ? -2.417  -29.249 -20.421 1.00 78.85  ? 408 ALA B C   1 
ATOM   6378  O O   . ALA B 1 408 ? -1.959  -30.084 -19.616 1.00 79.87  ? 408 ALA B O   1 
ATOM   6379  C CB  . ALA B 1 408 ? -3.269  -30.132 -22.605 1.00 66.56  ? 408 ALA B CB  1 
ATOM   6380  N N   . SER B 1 409 ? -1.882  -28.041 -20.623 1.00 89.66  ? 409 SER B N   1 
ATOM   6381  C CA  . SER B 1 409 ? -0.616  -27.672 -19.938 1.00 88.15  ? 409 SER B CA  1 
ATOM   6382  C C   . SER B 1 409 ? -0.826  -27.652 -18.419 1.00 97.89  ? 409 SER B C   1 
ATOM   6383  O O   . SER B 1 409 ? -1.856  -27.108 -17.967 1.00 99.66  ? 409 SER B O   1 
ATOM   6384  C CB  . SER B 1 409 ? -0.108  -26.344 -20.424 1.00 88.18  ? 409 SER B CB  1 
ATOM   6385  N N   . GLU B 1 410 ? 0.132   -28.201 -17.670 1.00 112.93 ? 410 GLU B N   1 
ATOM   6386  C CA  . GLU B 1 410 ? 0.043   -28.230 -16.187 1.00 131.12 ? 410 GLU B CA  1 
ATOM   6387  C C   . GLU B 1 410 ? 0.060   -26.803 -15.631 1.00 129.64 ? 410 GLU B C   1 
ATOM   6388  O O   . GLU B 1 410 ? -0.702  -26.532 -14.679 1.00 124.06 ? 410 GLU B O   1 
ATOM   6389  C CB  . GLU B 1 410 ? 1.199   -29.031 -15.591 1.00 142.45 ? 410 GLU B CB  1 
ATOM   6390  N N   . TYR B 1 411 ? 0.890   -25.930 -16.204 1.00 129.33 ? 411 TYR B N   1 
ATOM   6391  C CA  . TYR B 1 411 ? 1.042   -24.566 -15.633 1.00 125.42 ? 411 TYR B CA  1 
ATOM   6392  C C   . TYR B 1 411 ? 0.366   -23.549 -16.531 1.00 114.53 ? 411 TYR B C   1 
ATOM   6393  O O   . TYR B 1 411 ? 0.690   -23.468 -17.735 1.00 97.43  ? 411 TYR B O   1 
ATOM   6394  C CB  . TYR B 1 411 ? 2.516   -24.174 -15.468 1.00 131.68 ? 411 TYR B CB  1 
ATOM   6395  N N   . GLY B 1 412 ? -0.557  -22.776 -15.954 1.00 112.77 ? 412 GLY B N   1 
ATOM   6396  C CA  . GLY B 1 412 ? -1.208  -21.699 -16.720 1.00 110.12 ? 412 GLY B CA  1 
ATOM   6397  C C   . GLY B 1 412 ? -0.968  -20.365 -16.047 1.00 105.76 ? 412 GLY B C   1 
ATOM   6398  O O   . GLY B 1 412 ? -1.253  -20.258 -14.838 1.00 101.81 ? 412 GLY B O   1 
ATOM   6399  N N   . LEU B 1 413 ? -0.494  -19.375 -16.800 1.00 88.04  ? 413 LEU B N   1 
ATOM   6400  C CA  . LEU B 1 413 ? -0.294  -18.017 -16.242 1.00 83.45  ? 413 LEU B CA  1 
ATOM   6401  C C   . LEU B 1 413 ? -1.003  -17.040 -17.179 1.00 74.07  ? 413 LEU B C   1 
ATOM   6402  O O   . LEU B 1 413 ? -1.794  -16.208 -16.689 1.00 62.96  ? 413 LEU B O   1 
ATOM   6403  C CB  . LEU B 1 413 ? 1.200   -17.724 -16.133 1.00 99.47  ? 413 LEU B CB  1 
ATOM   6404  C CG  . LEU B 1 413 ? 1.582   -16.379 -15.509 1.00 107.63 ? 413 LEU B CG  1 
ATOM   6405  C CD1 . LEU B 1 413 ? 2.479   -16.590 -14.301 1.00 106.16 ? 413 LEU B CD1 1 
ATOM   6406  C CD2 . LEU B 1 413 ? 2.270   -15.498 -16.538 1.00 108.65 ? 413 LEU B CD2 1 
ATOM   6407  N N   . SER B 1 414 ? -0.737  -17.159 -18.482 1.00 69.66  ? 414 SER B N   1 
ATOM   6408  C CA  . SER B 1 414 ? -1.461  -16.315 -19.434 1.00 53.09  ? 414 SER B CA  1 
ATOM   6409  C C   . SER B 1 414 ? -2.088  -17.163 -20.551 1.00 49.00  ? 414 SER B C   1 
ATOM   6410  O O   . SER B 1 414 ? -1.740  -18.327 -20.729 1.00 53.23  ? 414 SER B O   1 
ATOM   6411  C CB  . SER B 1 414 ? -0.566  -15.266 -20.001 1.00 54.59  ? 414 SER B CB  1 
ATOM   6412  O OG  . SER B 1 414 ? -1.318  -14.251 -20.668 1.00 61.37  ? 414 SER B OG  1 
ATOM   6413  N N   . SER B 1 415 ? -3.017  -16.542 -21.306 1.00 49.17  ? 415 SER B N   1 
ATOM   6414  C CA  . SER B 1 415 ? -3.724  -17.191 -22.406 1.00 46.49  ? 415 SER B CA  1 
ATOM   6415  C C   . SER B 1 415 ? -4.359  -16.136 -23.307 1.00 43.52  ? 415 SER B C   1 
ATOM   6416  O O   . SER B 1 415 ? -4.474  -14.969 -22.916 1.00 41.37  ? 415 SER B O   1 
ATOM   6417  C CB  . SER B 1 415 ? -4.764  -18.160 -21.893 1.00 47.58  ? 415 SER B CB  1 
ATOM   6418  O OG  . SER B 1 415 ? -5.629  -17.523 -20.966 1.00 47.08  ? 415 SER B OG  1 
ATOM   6419  N N   . ALA B 1 416 ? -4.753  -16.552 -24.534 1.00 42.92  ? 416 ALA B N   1 
ATOM   6420  C CA  . ALA B 1 416 ? -5.462  -15.663 -25.459 1.00 42.39  ? 416 ALA B CA  1 
ATOM   6421  C C   . ALA B 1 416 ? -6.473  -16.450 -26.296 1.00 41.83  ? 416 ALA B C   1 
ATOM   6422  O O   . ALA B 1 416 ? -6.250  -17.606 -26.635 1.00 42.69  ? 416 ALA B O   1 
ATOM   6423  C CB  . ALA B 1 416 ? -4.486  -14.936 -26.330 1.00 43.76  ? 416 ALA B CB  1 
ATOM   6424  N N   . VAL B 1 417 ? -7.584  -15.799 -26.612 1.00 41.93  ? 417 VAL B N   1 
ATOM   6425  C CA  . VAL B 1 417 ? -8.656  -16.406 -27.377 1.00 44.76  ? 417 VAL B CA  1 
ATOM   6426  C C   . VAL B 1 417 ? -9.073  -15.419 -28.441 1.00 44.36  ? 417 VAL B C   1 
ATOM   6427  O O   . VAL B 1 417 ? -9.295  -14.243 -28.146 1.00 49.55  ? 417 VAL B O   1 
ATOM   6428  C CB  . VAL B 1 417 ? -9.872  -16.814 -26.522 1.00 46.86  ? 417 VAL B CB  1 
ATOM   6429  C CG1 . VAL B 1 417 ? -10.955 -17.445 -27.370 1.00 55.11  ? 417 VAL B CG1 1 
ATOM   6430  C CG2 . VAL B 1 417 ? -9.491  -17.754 -25.383 1.00 52.56  ? 417 VAL B CG2 1 
ATOM   6431  N N   . PHE B 1 418 ? -9.195  -15.908 -29.675 1.00 47.14  ? 418 PHE B N   1 
ATOM   6432  C CA  . PHE B 1 418 ? -9.565  -15.063 -30.804 1.00 59.39  ? 418 PHE B CA  1 
ATOM   6433  C C   . PHE B 1 418 ? -10.869 -15.570 -31.422 1.00 54.58  ? 418 PHE B C   1 
ATOM   6434  O O   . PHE B 1 418 ? -10.959 -16.718 -31.843 1.00 56.21  ? 418 PHE B O   1 
ATOM   6435  C CB  . PHE B 1 418 ? -8.415  -14.999 -31.816 1.00 62.09  ? 418 PHE B CB  1 
ATOM   6436  C CG  . PHE B 1 418 ? -7.593  -13.721 -31.731 1.00 66.15  ? 418 PHE B CG  1 
ATOM   6437  C CD1 . PHE B 1 418 ? -6.417  -13.665 -30.981 1.00 73.37  ? 418 PHE B CD1 1 
ATOM   6438  C CD2 . PHE B 1 418 ? -8.024  -12.565 -32.359 1.00 68.34  ? 418 PHE B CD2 1 
ATOM   6439  C CE1 . PHE B 1 418 ? -5.692  -12.487 -30.892 1.00 75.94  ? 418 PHE B CE1 1 
ATOM   6440  C CE2 . PHE B 1 418 ? -7.282  -11.397 -32.280 1.00 74.39  ? 418 PHE B CE2 1 
ATOM   6441  C CZ  . PHE B 1 418 ? -6.124  -11.360 -31.549 1.00 74.88  ? 418 PHE B CZ  1 
ATOM   6442  N N   . SER B 1 419 ? -11.865 -14.679 -31.480 1.00 55.67  ? 419 SER B N   1 
ATOM   6443  C CA  . SER B 1 419 ? -13.183 -14.999 -32.018 1.00 59.99  ? 419 SER B CA  1 
ATOM   6444  C C   . SER B 1 419 ? -13.991 -13.708 -32.168 1.00 66.05  ? 419 SER B C   1 
ATOM   6445  O O   . SER B 1 419 ? -13.932 -12.839 -31.302 1.00 72.59  ? 419 SER B O   1 
ATOM   6446  C CB  . SER B 1 419 ? -13.906 -16.008 -31.136 1.00 58.50  ? 419 SER B CB  1 
ATOM   6447  O OG  . SER B 1 419 ? -15.312 -15.800 -31.154 1.00 66.22  ? 419 SER B OG  1 
ATOM   6448  N N   . ARG B 1 420 ? -14.768 -13.603 -33.255 1.00 66.76  ? 420 ARG B N   1 
ATOM   6449  C CA  . ARG B 1 420 ? -15.561 -12.399 -33.515 1.00 71.00  ? 420 ARG B CA  1 
ATOM   6450  C C   . ARG B 1 420 ? -16.795 -12.370 -32.605 1.00 67.19  ? 420 ARG B C   1 
ATOM   6451  O O   . ARG B 1 420 ? -17.345 -11.304 -32.344 1.00 67.64  ? 420 ARG B O   1 
ATOM   6452  C CB  . ARG B 1 420 ? -15.974 -12.292 -34.983 1.00 76.25  ? 420 ARG B CB  1 
ATOM   6453  C CG  . ARG B 1 420 ? -14.898 -12.810 -35.928 1.00 85.43  ? 420 ARG B CG  1 
ATOM   6454  C CD  . ARG B 1 420 ? -15.139 -12.452 -37.406 1.00 84.14  ? 420 ARG B CD  1 
ATOM   6455  N NE  . ARG B 1 420 ? -15.082 -11.007 -37.651 1.00 92.95  ? 420 ARG B NE  1 
ATOM   6456  C CZ  . ARG B 1 420 ? -14.426 -10.409 -38.654 1.00 96.35  ? 420 ARG B CZ  1 
ATOM   6457  N NH1 . ARG B 1 420 ? -13.770 -11.128 -39.555 1.00 95.02  ? 420 ARG B NH1 1 
ATOM   6458  N NH2 . ARG B 1 420 ? -14.480 -9.091  -38.774 1.00 85.93  ? 420 ARG B NH2 1 
ATOM   6459  N N   . ASP B 1 421 ? -17.208 -13.539 -32.100 1.00 59.14  ? 421 ASP B N   1 
ATOM   6460  C CA  . ASP B 1 421 ? -18.306 -13.598 -31.140 1.00 65.64  ? 421 ASP B CA  1 
ATOM   6461  C C   . ASP B 1 421 ? -17.759 -13.405 -29.721 1.00 67.69  ? 421 ASP B C   1 
ATOM   6462  O O   . ASP B 1 421 ? -17.207 -14.336 -29.132 1.00 62.12  ? 421 ASP B O   1 
ATOM   6463  C CB  . ASP B 1 421 ? -19.083 -14.895 -31.265 1.00 68.60  ? 421 ASP B CB  1 
ATOM   6464  C CG  . ASP B 1 421 ? -20.318 -15.005 -30.387 1.00 66.03  ? 421 ASP B CG  1 
ATOM   6465  O OD1 . ASP B 1 421 ? -20.678 -13.994 -29.749 1.00 68.66  ? 421 ASP B OD1 1 
ATOM   6466  O OD2 . ASP B 1 421 ? -20.901 -16.109 -30.339 1.00 71.09  ? 421 ASP B OD2 1 
ATOM   6467  N N   . LEU B 1 422 ? -17.987 -12.210 -29.158 1.00 64.19  ? 422 LEU B N   1 
ATOM   6468  C CA  . LEU B 1 422 ? -17.427 -11.855 -27.861 1.00 68.68  ? 422 LEU B CA  1 
ATOM   6469  C C   . LEU B 1 422 ? -18.036 -12.720 -26.751 1.00 75.71  ? 422 LEU B C   1 
ATOM   6470  O O   . LEU B 1 422 ? -17.334 -13.113 -25.822 1.00 78.78  ? 422 LEU B O   1 
ATOM   6471  C CB  . LEU B 1 422 ? -17.623 -10.372 -27.579 1.00 64.73  ? 422 LEU B CB  1 
ATOM   6472  C CG  . LEU B 1 422 ? -16.774 -9.416  -28.415 1.00 65.65  ? 422 LEU B CG  1 
ATOM   6473  C CD1 . LEU B 1 422 ? -16.517 -8.134  -27.642 1.00 69.74  ? 422 LEU B CD1 1 
ATOM   6474  C CD2 . LEU B 1 422 ? -15.475 -10.046 -28.836 1.00 67.61  ? 422 LEU B CD2 1 
ATOM   6475  N N   . GLU B 1 423 ? -19.341 -13.005 -26.841 1.00 77.31  ? 423 GLU B N   1 
ATOM   6476  C CA  . GLU B 1 423 ? -20.003 -13.779 -25.799 1.00 80.68  ? 423 GLU B CA  1 
ATOM   6477  C C   . GLU B 1 423 ? -19.405 -15.193 -25.763 1.00 72.77  ? 423 GLU B C   1 
ATOM   6478  O O   . GLU B 1 423 ? -19.072 -15.694 -24.696 1.00 68.23  ? 423 GLU B O   1 
ATOM   6479  C CB  . GLU B 1 423 ? -21.527 -13.824 -25.960 1.00 79.56  ? 423 GLU B CB  1 
ATOM   6480  C CG  . GLU B 1 423 ? -22.252 -13.719 -24.618 1.00 85.95  ? 423 GLU B CG  1 
ATOM   6481  C CD  . GLU B 1 423 ? -23.591 -14.426 -24.533 1.00 98.94  ? 423 GLU B CD  1 
ATOM   6482  O OE1 . GLU B 1 423 ? -24.383 -14.306 -25.494 1.00 118.29 ? 423 GLU B OE1 1 
ATOM   6483  O OE2 . GLU B 1 423 ? -23.864 -15.065 -23.481 1.00 86.74  ? 423 GLU B OE2 1 
ATOM   6484  N N   . ARG B 1 424 ? -19.255 -15.810 -26.946 1.00 67.01  ? 424 ARG B N   1 
ATOM   6485  C CA  . ARG B 1 424 ? -18.659 -17.133 -27.057 1.00 63.78  ? 424 ARG B CA  1 
ATOM   6486  C C   . ARG B 1 424 ? -17.202 -17.090 -26.594 1.00 65.70  ? 424 ARG B C   1 
ATOM   6487  O O   . ARG B 1 424 ? -16.756 -17.969 -25.854 1.00 66.75  ? 424 ARG B O   1 
ATOM   6488  C CB  . ARG B 1 424 ? -18.736 -17.635 -28.495 1.00 67.43  ? 424 ARG B CB  1 
ATOM   6489  C CG  . ARG B 1 424 ? -18.045 -18.962 -28.739 1.00 69.92  ? 424 ARG B CG  1 
ATOM   6490  C CD  . ARG B 1 424 ? -17.349 -18.947 -30.068 1.00 71.19  ? 424 ARG B CD  1 
ATOM   6491  N NE  . ARG B 1 424 ? -17.204 -20.293 -30.627 1.00 73.10  ? 424 ARG B NE  1 
ATOM   6492  C CZ  . ARG B 1 424 ? -16.715 -20.554 -31.833 1.00 79.70  ? 424 ARG B CZ  1 
ATOM   6493  N NH1 . ARG B 1 424 ? -16.343 -19.563 -32.625 1.00 88.49  ? 424 ARG B NH1 1 
ATOM   6494  N NH2 . ARG B 1 424 ? -16.608 -21.804 -32.250 1.00 83.72  ? 424 ARG B NH2 1 
ATOM   6495  N N   . ALA B 1 425 ? -16.469 -16.055 -27.022 1.00 59.27  ? 425 ALA B N   1 
ATOM   6496  C CA  . ALA B 1 425 ? -15.051 -15.943 -26.710 1.00 59.42  ? 425 ALA B CA  1 
ATOM   6497  C C   . ALA B 1 425 ? -14.847 -15.841 -25.198 1.00 51.93  ? 425 ALA B C   1 
ATOM   6498  O O   . ALA B 1 425 ? -13.988 -16.507 -24.636 1.00 43.89  ? 425 ALA B O   1 
ATOM   6499  C CB  . ALA B 1 425 ? -14.454 -14.761 -27.430 1.00 61.26  ? 425 ALA B CB  1 
ATOM   6500  N N   . VAL B 1 426 ? -15.657 -15.022 -24.548 1.00 49.69  ? 426 VAL B N   1 
ATOM   6501  C CA  . VAL B 1 426 ? -15.524 -14.811 -23.125 1.00 47.50  ? 426 VAL B CA  1 
ATOM   6502  C C   . VAL B 1 426 ? -15.965 -16.070 -22.382 1.00 49.92  ? 426 VAL B C   1 
ATOM   6503  O O   . VAL B 1 426 ? -15.369 -16.437 -21.363 1.00 46.63  ? 426 VAL B O   1 
ATOM   6504  C CB  . VAL B 1 426 ? -16.304 -13.579 -22.669 1.00 47.37  ? 426 VAL B CB  1 
ATOM   6505  C CG1 . VAL B 1 426 ? -16.415 -13.512 -21.150 1.00 47.96  ? 426 VAL B CG1 1 
ATOM   6506  C CG2 . VAL B 1 426 ? -15.683 -12.299 -23.223 1.00 53.45  ? 426 VAL B CG2 1 
ATOM   6507  N N   . ARG B 1 427 ? -17.001 -16.732 -22.892 1.00 52.92  ? 427 ARG B N   1 
ATOM   6508  C CA  . ARG B 1 427 ? -17.481 -17.968 -22.280 1.00 59.79  ? 427 ARG B CA  1 
ATOM   6509  C C   . ARG B 1 427 ? -16.368 -19.015 -22.337 1.00 57.41  ? 427 ARG B C   1 
ATOM   6510  O O   . ARG B 1 427 ? -16.136 -19.726 -21.362 1.00 63.57  ? 427 ARG B O   1 
ATOM   6511  C CB  . ARG B 1 427 ? -18.740 -18.478 -22.984 1.00 50.00  ? 427 ARG B CB  1 
ATOM   6512  C CG  . ARG B 1 427 ? -18.502 -19.677 -23.888 1.00 50.00  ? 427 ARG B CG  1 
ATOM   6513  C CD  . ARG B 1 427 ? -19.743 -20.155 -24.625 1.00 50.00  ? 427 ARG B CD  1 
ATOM   6514  N NE  . ARG B 1 427 ? -20.955 -19.976 -23.831 1.00 50.00  ? 427 ARG B NE  1 
ATOM   6515  C CZ  . ARG B 1 427 ? -22.180 -20.203 -24.280 1.00 50.00  ? 427 ARG B CZ  1 
ATOM   6516  N NH1 . ARG B 1 427 ? -22.365 -20.626 -25.525 1.00 50.00  ? 427 ARG B NH1 1 
ATOM   6517  N NH2 . ARG B 1 427 ? -23.227 -20.013 -23.487 1.00 50.00  ? 427 ARG B NH2 1 
ATOM   6518  N N   . PHE B 1 428 ? -15.694 -19.104 -23.500 1.00 52.14  ? 428 PHE B N   1 
ATOM   6519  C CA  . PHE B 1 428 ? -14.554 -19.993 -23.668 1.00 53.11  ? 428 PHE B CA  1 
ATOM   6520  C C   . PHE B 1 428 ? -13.475 -19.614 -22.666 1.00 49.71  ? 428 PHE B C   1 
ATOM   6521  O O   . PHE B 1 428 ? -12.951 -20.476 -21.962 1.00 52.92  ? 428 PHE B O   1 
ATOM   6522  C CB  . PHE B 1 428 ? -13.997 -19.933 -25.092 1.00 51.12  ? 428 PHE B CB  1 
ATOM   6523  C CG  . PHE B 1 428 ? -12.863 -20.905 -25.368 1.00 50.29  ? 428 PHE B CG  1 
ATOM   6524  C CD1 . PHE B 1 428 ? -11.550 -20.581 -25.039 1.00 55.89  ? 428 PHE B CD1 1 
ATOM   6525  C CD2 . PHE B 1 428 ? -13.103 -22.133 -25.987 1.00 54.09  ? 428 PHE B CD2 1 
ATOM   6526  C CE1 . PHE B 1 428 ? -10.500 -21.470 -25.305 1.00 56.42  ? 428 PHE B CE1 1 
ATOM   6527  C CE2 . PHE B 1 428 ? -12.050 -23.014 -26.266 1.00 58.97  ? 428 PHE B CE2 1 
ATOM   6528  C CZ  . PHE B 1 428 ? -10.754 -22.678 -25.923 1.00 57.17  ? 428 PHE B CZ  1 
ATOM   6529  N N   . ALA B 1 429 ? -13.151 -18.316 -22.612 1.00 45.67  ? 429 ALA B N   1 
ATOM   6530  C CA  . ALA B 1 429 ? -12.039 -17.834 -21.809 1.00 47.06  ? 429 ALA B CA  1 
ATOM   6531  C C   . ALA B 1 429 ? -12.239 -18.218 -20.342 1.00 45.30  ? 429 ALA B C   1 
ATOM   6532  O O   . ALA B 1 429 ? -11.286 -18.602 -19.674 1.00 43.67  ? 429 ALA B O   1 
ATOM   6533  C CB  . ALA B 1 429 ? -11.879 -16.337 -21.978 1.00 46.05  ? 429 ALA B CB  1 
ATOM   6534  N N   . ARG B 1 430 ? -13.490 -18.145 -19.863 1.00 45.34  ? 430 ARG B N   1 
ATOM   6535  C CA  . ARG B 1 430 ? -13.793 -18.425 -18.463 1.00 50.99  ? 430 ARG B CA  1 
ATOM   6536  C C   . ARG B 1 430 ? -13.511 -19.898 -18.121 1.00 54.51  ? 430 ARG B C   1 
ATOM   6537  O O   . ARG B 1 430 ? -13.309 -20.229 -16.959 1.00 61.47  ? 430 ARG B O   1 
ATOM   6538  C CB  . ARG B 1 430 ? -15.226 -18.049 -18.119 1.00 52.66  ? 430 ARG B CB  1 
ATOM   6539  C CG  . ARG B 1 430 ? -15.431 -16.545 -18.003 1.00 54.13  ? 430 ARG B CG  1 
ATOM   6540  C CD  . ARG B 1 430 ? -16.733 -16.213 -17.331 1.00 57.00  ? 430 ARG B CD  1 
ATOM   6541  N NE  . ARG B 1 430 ? -16.662 -16.495 -15.896 1.00 66.17  ? 430 ARG B NE  1 
ATOM   6542  C CZ  . ARG B 1 430 ? -17.628 -16.224 -15.018 1.00 66.47  ? 430 ARG B CZ  1 
ATOM   6543  N NH1 . ARG B 1 430 ? -18.828 -15.814 -15.440 1.00 58.25  ? 430 ARG B NH1 1 
ATOM   6544  N NH2 . ARG B 1 430 ? -17.392 -16.370 -13.722 1.00 61.79  ? 430 ARG B NH2 1 
ATOM   6545  N N   . GLN B 1 431 ? -13.431 -20.765 -19.135 1.00 49.22  ? 431 GLN B N   1 
ATOM   6546  C CA  . GLN B 1 431 ? -13.193 -22.178 -18.890 1.00 51.25  ? 431 GLN B CA  1 
ATOM   6547  C C   . GLN B 1 431 ? -11.694 -22.464 -18.825 1.00 51.46  ? 431 GLN B C   1 
ATOM   6548  O O   . GLN B 1 431 ? -11.292 -23.531 -18.382 1.00 54.72  ? 431 GLN B O   1 
ATOM   6549  C CB  . GLN B 1 431 ? -13.883 -23.035 -19.937 1.00 55.71  ? 431 GLN B CB  1 
ATOM   6550  C CG  . GLN B 1 431 ? -15.307 -22.587 -20.221 1.00 68.09  ? 431 GLN B CG  1 
ATOM   6551  C CD  . GLN B 1 431 ? -16.238 -23.733 -20.489 1.00 81.48  ? 431 GLN B CD  1 
ATOM   6552  O OE1 . GLN B 1 431 ? -16.240 -24.728 -19.758 1.00 82.62  ? 431 GLN B OE1 1 
ATOM   6553  N NE2 . GLN B 1 431 ? -17.034 -23.615 -21.554 1.00 81.93  ? 431 GLN B NE2 1 
ATOM   6554  N N   . LEU B 1 432 ? -10.871 -21.521 -19.273 1.00 53.02  ? 432 LEU B N   1 
ATOM   6555  C CA  . LEU B 1 432 ? -9.429  -21.747 -19.313 1.00 52.58  ? 432 LEU B CA  1 
ATOM   6556  C C   . LEU B 1 432 ? -8.864  -21.768 -17.892 1.00 55.10  ? 432 LEU B C   1 
ATOM   6557  O O   . LEU B 1 432 ? -9.237  -20.953 -17.054 1.00 57.74  ? 432 LEU B O   1 
ATOM   6558  C CB  . LEU B 1 432 ? -8.730  -20.693 -20.166 1.00 47.10  ? 432 LEU B CB  1 
ATOM   6559  C CG  . LEU B 1 432 ? -8.976  -20.778 -21.673 1.00 47.47  ? 432 LEU B CG  1 
ATOM   6560  C CD1 . LEU B 1 432 ? -8.279  -19.647 -22.398 1.00 48.68  ? 432 LEU B CD1 1 
ATOM   6561  C CD2 . LEU B 1 432 ? -8.532  -22.095 -22.237 1.00 49.25  ? 432 LEU B CD2 1 
ATOM   6562  N N   . ARG B 1 433 ? -7.928  -22.693 -17.669 1.00 60.39  ? 433 ARG B N   1 
ATOM   6563  C CA  . ARG B 1 433 ? -7.185  -22.812 -16.418 1.00 71.04  ? 433 ARG B CA  1 
ATOM   6564  C C   . ARG B 1 433 ? -6.085  -21.748 -16.356 1.00 67.99  ? 433 ARG B C   1 
ATOM   6565  O O   . ARG B 1 433 ? -4.899  -22.078 -16.363 1.00 72.88  ? 433 ARG B O   1 
ATOM   6566  C CB  . ARG B 1 433 ? -6.440  -24.161 -16.356 1.00 81.42  ? 433 ARG B CB  1 
ATOM   6567  N N   . ALA B 1 434 ? -6.449  -20.489 -16.334 1.00 58.36  ? 434 ALA B N   1 
ATOM   6568  C CA  . ALA B 1 434 ? -5.427  -19.474 -16.436 1.00 51.71  ? 434 ALA B CA  1 
ATOM   6569  C C   . ALA B 1 434 ? -5.799  -18.260 -15.616 1.00 49.80  ? 434 ALA B C   1 
ATOM   6570  O O   . ALA B 1 434 ? -6.968  -17.961 -15.418 1.00 57.14  ? 434 ALA B O   1 
ATOM   6571  C CB  . ALA B 1 434 ? -5.177  -19.128 -17.879 1.00 54.86  ? 434 ALA B CB  1 
ATOM   6572  N N   . GLY B 1 435 ? -4.777  -17.592 -15.109 1.00 47.45  ? 435 GLY B N   1 
ATOM   6573  C CA  . GLY B 1 435 ? -4.949  -16.412 -14.306 1.00 43.91  ? 435 GLY B CA  1 
ATOM   6574  C C   . GLY B 1 435 ? -5.353  -15.215 -15.154 1.00 48.85  ? 435 GLY B C   1 
ATOM   6575  O O   . GLY B 1 435 ? -6.043  -14.336 -14.673 1.00 45.50  ? 435 GLY B O   1 
ATOM   6576  N N   . MET B 1 436 ? -4.900  -15.189 -16.415 1.00 52.68  ? 436 MET B N   1 
ATOM   6577  C CA  . MET B 1 436 ? -5.108  -14.040 -17.294 1.00 54.27  ? 436 MET B CA  1 
ATOM   6578  C C   . MET B 1 436 ? -5.463  -14.548 -18.678 1.00 49.06  ? 436 MET B C   1 
ATOM   6579  O O   . MET B 1 436 ? -4.795  -15.429 -19.181 1.00 44.31  ? 436 MET B O   1 
ATOM   6580  C CB  . MET B 1 436 ? -3.833  -13.210 -17.399 1.00 59.98  ? 436 MET B CB  1 
ATOM   6581  C CG  . MET B 1 436 ? -4.049  -11.769 -17.740 1.00 71.81  ? 436 MET B CG  1 
ATOM   6582  S SD  . MET B 1 436 ? -2.731  -10.776 -17.015 1.00 110.55 ? 436 MET B SD  1 
ATOM   6583  C CE  . MET B 1 436 ? -1.245  -11.606 -17.615 1.00 107.34 ? 436 MET B CE  1 
ATOM   6584  N N   . THR B 1 437 ? -6.510  -13.978 -19.295 1.00 41.13  ? 437 THR B N   1 
ATOM   6585  C CA  . THR B 1 437 ? -6.819  -14.274 -20.692 1.00 42.61  ? 437 THR B CA  1 
ATOM   6586  C C   . THR B 1 437 ? -7.019  -12.975 -21.471 1.00 39.70  ? 437 THR B C   1 
ATOM   6587  O O   . THR B 1 437 ? -7.786  -12.119 -21.059 1.00 41.88  ? 437 THR B O   1 
ATOM   6588  C CB  . THR B 1 437 ? -8.063  -15.154 -20.822 1.00 47.98  ? 437 THR B CB  1 
ATOM   6589  O OG1 . THR B 1 437 ? -7.990  -16.254 -19.908 1.00 44.11  ? 437 THR B OG1 1 
ATOM   6590  C CG2 . THR B 1 437 ? -8.202  -15.673 -22.243 1.00 46.80  ? 437 THR B CG2 1 
ATOM   6591  N N   . HIS B 1 438 ? -6.441  -12.911 -22.676 1.00 43.42  ? 438 HIS B N   1 
ATOM   6592  C CA  . HIS B 1 438 ? -6.680  -11.785 -23.591 1.00 45.66  ? 438 HIS B CA  1 
ATOM   6593  C C   . HIS B 1 438 ? -7.658  -12.209 -24.696 1.00 39.85  ? 438 HIS B C   1 
ATOM   6594  O O   . HIS B 1 438 ? -7.420  -13.188 -25.385 1.00 43.53  ? 438 HIS B O   1 
ATOM   6595  C CB  . HIS B 1 438 ? -5.360  -11.282 -24.194 1.00 54.50  ? 438 HIS B CB  1 
ATOM   6596  C CG  . HIS B 1 438 ? -4.439  -10.635 -23.211 1.00 60.80  ? 438 HIS B CG  1 
ATOM   6597  N ND1 . HIS B 1 438 ? -4.420  -9.274  -22.961 1.00 67.69  ? 438 HIS B ND1 1 
ATOM   6598  C CD2 . HIS B 1 438 ? -3.512  -11.175 -22.398 1.00 59.12  ? 438 HIS B CD2 1 
ATOM   6599  C CE1 . HIS B 1 438 ? -3.524  -9.018  -22.023 1.00 64.01  ? 438 HIS B CE1 1 
ATOM   6600  N NE2 . HIS B 1 438 ? -2.952  -10.157 -21.678 1.00 59.57  ? 438 HIS B NE2 1 
ATOM   6601  N N   . VAL B 1 439 ? -8.749  -11.440 -24.875 1.00 44.24  ? 439 VAL B N   1 
ATOM   6602  C CA  . VAL B 1 439 ? -9.712  -11.696 -25.964 1.00 47.74  ? 439 VAL B CA  1 
ATOM   6603  C C   . VAL B 1 439 ? -9.532  -10.656 -27.081 1.00 46.84  ? 439 VAL B C   1 
ATOM   6604  O O   . VAL B 1 439 ? -9.763  -9.458  -26.866 1.00 41.43  ? 439 VAL B O   1 
ATOM   6605  C CB  . VAL B 1 439 ? -11.156 -11.684 -25.455 1.00 49.00  ? 439 VAL B CB  1 
ATOM   6606  C CG1 . VAL B 1 439 ? -12.145 -11.745 -26.606 1.00 54.12  ? 439 VAL B CG1 1 
ATOM   6607  C CG2 . VAL B 1 439 ? -11.416 -12.803 -24.464 1.00 46.26  ? 439 VAL B CG2 1 
ATOM   6608  N N   . ASN B 1 440 ? -9.132  -11.137 -28.273 1.00 54.74  ? 440 ASN B N   1 
ATOM   6609  C CA  . ASN B 1 440 ? -9.026  -10.306 -29.484 1.00 62.36  ? 440 ASN B CA  1 
ATOM   6610  C C   . ASN B 1 440 ? -8.003  -9.168  -29.302 1.00 63.19  ? 440 ASN B C   1 
ATOM   6611  O O   . ASN B 1 440 ? -8.123  -8.136  -29.936 1.00 60.74  ? 440 ASN B O   1 
ATOM   6612  C CB  . ASN B 1 440 ? -10.376 -9.719  -29.909 1.00 51.60  ? 440 ASN B CB  1 
ATOM   6613  C CG  . ASN B 1 440 ? -11.361 -10.770 -30.382 1.00 54.79  ? 440 ASN B CG  1 
ATOM   6614  O OD1 . ASN B 1 440 ? -11.000 -11.935 -30.582 1.00 58.17  ? 440 ASN B OD1 1 
ATOM   6615  N ND2 . ASN B 1 440 ? -12.607 -10.378 -30.571 1.00 54.29  ? 440 ASN B ND2 1 
ATOM   6616  N N   . ASP B 1 441 ? -6.974  -9.385  -28.486 1.00 73.65  ? 441 ASP B N   1 
ATOM   6617  C CA  . ASP B 1 441 ? -5.978  -8.352  -28.260 1.00 91.39  ? 441 ASP B CA  1 
ATOM   6618  C C   . ASP B 1 441 ? -4.581  -8.922  -28.450 1.00 109.42 ? 441 ASP B C   1 
ATOM   6619  O O   . ASP B 1 441 ? -4.291  -10.044 -28.013 1.00 108.24 ? 441 ASP B O   1 
ATOM   6620  C CB  . ASP B 1 441 ? -6.118  -7.710  -26.891 1.00 104.83 ? 441 ASP B CB  1 
ATOM   6621  C CG  . ASP B 1 441 ? -5.627  -6.266  -26.809 1.00 115.05 ? 441 ASP B CG  1 
ATOM   6622  O OD1 . ASP B 1 441 ? -4.423  -6.034  -27.047 1.00 115.30 ? 441 ASP B OD1 1 
ATOM   6623  O OD2 . ASP B 1 441 ? -6.460  -5.381  -26.552 1.00 115.76 ? 441 ASP B OD2 1 
ATOM   6624  N N   . ILE B 1 442 ? -3.711  -8.106  -29.073 1.00 133.16 ? 442 ILE B N   1 
ATOM   6625  C CA  . ILE B 1 442 ? -2.293  -8.416  -29.199 1.00 143.68 ? 442 ILE B CA  1 
ATOM   6626  C C   . ILE B 1 442 ? -1.681  -8.433  -27.786 1.00 144.78 ? 442 ILE B C   1 
ATOM   6627  O O   . ILE B 1 442 ? -1.634  -7.404  -27.121 1.00 149.25 ? 442 ILE B O   1 
ATOM   6628  C CB  . ILE B 1 442 ? -1.580  -7.409  -30.161 1.00 132.41 ? 442 ILE B CB  1 
ATOM   6629  C CG1 . ILE B 1 442 ? -1.528  -5.971  -29.592 1.00 128.93 ? 442 ILE B CG1 1 
ATOM   6630  C CG2 . ILE B 1 442 ? -2.220  -7.425  -31.555 1.00 115.63 ? 442 ILE B CG2 1 
ATOM   6631  C CD1 . ILE B 1 442 ? -0.851  -4.964  -30.512 1.00 122.34 ? 442 ILE B CD1 1 
ATOM   6632  N N   . PRO B 1 443 ? -1.289  -9.618  -27.245 1.00 141.38 ? 443 PRO B N   1 
ATOM   6633  C CA  . PRO B 1 443 ? -0.851  -9.715  -25.849 1.00 136.88 ? 443 PRO B CA  1 
ATOM   6634  C C   . PRO B 1 443 ? 0.542   -9.144  -25.614 1.00 123.09 ? 443 PRO B C   1 
ATOM   6635  O O   . PRO B 1 443 ? 0.816   -8.824  -24.442 1.00 104.34 ? 443 PRO B O   1 
ATOM   6636  C CB  . PRO B 1 443 ? -0.912  -11.225 -25.586 1.00 135.82 ? 443 PRO B CB  1 
ATOM   6637  C CG  . PRO B 1 443 ? -0.611  -11.841 -26.929 1.00 138.22 ? 443 PRO B CG  1 
ATOM   6638  C CD  . PRO B 1 443 ? -1.260  -10.911 -27.940 1.00 136.66 ? 443 PRO B CD  1 
ATOM   6639  N N   . GLY B 1 459 ? -0.764  0.579   -16.361 1.00 88.26  ? 459 GLY B N   1 
ATOM   6640  C CA  . GLY B 1 459 ? -0.636  0.033   -14.992 1.00 94.06  ? 459 GLY B CA  1 
ATOM   6641  C C   . GLY B 1 459 ? -1.972  -0.502  -14.443 1.00 98.91  ? 459 GLY B C   1 
ATOM   6642  O O   . GLY B 1 459 ? -2.079  -0.774  -13.248 1.00 91.51  ? 459 GLY B O   1 
ATOM   6643  N N   . LEU B 1 460 ? -2.941  -0.747  -15.339 1.00 102.16 ? 460 LEU B N   1 
ATOM   6644  C CA  . LEU B 1 460 ? -4.324  -1.029  -14.953 1.00 97.57  ? 460 LEU B CA  1 
ATOM   6645  C C   . LEU B 1 460 ? -4.575  -2.545  -14.847 1.00 97.58  ? 460 LEU B C   1 
ATOM   6646  O O   . LEU B 1 460 ? -5.490  -2.972  -14.153 1.00 118.03 ? 460 LEU B O   1 
ATOM   6647  C CB  . LEU B 1 460 ? -5.240  -0.378  -15.980 1.00 92.26  ? 460 LEU B CB  1 
ATOM   6648  C CG  . LEU B 1 460 ? -5.038  1.125   -16.183 1.00 89.31  ? 460 LEU B CG  1 
ATOM   6649  C CD1 . LEU B 1 460 ? -5.593  1.588   -17.527 1.00 89.89  ? 460 LEU B CD1 1 
ATOM   6650  C CD2 . LEU B 1 460 ? -5.662  1.897   -15.054 1.00 85.03  ? 460 LEU B CD2 1 
ATOM   6651  N N   . GLY B 1 461 ? -3.757  -3.342  -15.539 1.00 97.60  ? 461 GLY B N   1 
ATOM   6652  C CA  . GLY B 1 461 ? -3.860  -4.791  -15.489 1.00 110.90 ? 461 GLY B CA  1 
ATOM   6653  C C   . GLY B 1 461 ? -2.923  -5.383  -14.431 1.00 119.26 ? 461 GLY B C   1 
ATOM   6654  O O   . GLY B 1 461 ? -1.715  -5.123  -14.451 1.00 136.50 ? 461 GLY B O   1 
ATOM   6655  N N   . ARG B 1 462 ? -3.495  -6.239  -13.554 1.00 108.22 ? 462 ARG B N   1 
ATOM   6656  C CA  . ARG B 1 462 ? -2.781  -6.832  -12.423 1.00 102.23 ? 462 ARG B CA  1 
ATOM   6657  C C   . ARG B 1 462 ? -2.000  -5.736  -11.707 1.00 110.71 ? 462 ARG B C   1 
ATOM   6658  O O   . ARG B 1 462 ? -2.472  -4.599  -11.607 1.00 137.00 ? 462 ARG B O   1 
ATOM   6659  C CB  . ARG B 1 462 ? -1.898  -8.004  -12.893 1.00 96.94  ? 462 ARG B CB  1 
ATOM   6660  C CG  . ARG B 1 462 ? -2.617  -9.335  -13.075 1.00 95.28  ? 462 ARG B CG  1 
ATOM   6661  C CD  . ARG B 1 462 ? -2.451  -10.235 -11.864 1.00 100.26 ? 462 ARG B CD  1 
ATOM   6662  N NE  . ARG B 1 462 ? -3.095  -11.542 -12.064 1.00 116.15 ? 462 ARG B NE  1 
ATOM   6663  C CZ  . ARG B 1 462 ? -4.055  -12.073 -11.281 1.00 122.97 ? 462 ARG B CZ  1 
ATOM   6664  N NH1 . ARG B 1 462 ? -4.484  -11.419 -10.215 1.00 133.98 ? 462 ARG B NH1 1 
ATOM   6665  N NH2 . ARG B 1 462 ? -4.569  -13.265 -11.567 1.00 104.91 ? 462 ARG B NH2 1 
ATOM   6666  N N   . PHE B 1 463 ? -0.805  -6.083  -11.211 1.00 96.89  ? 463 PHE B N   1 
ATOM   6667  C CA  . PHE B 1 463 ? 0.023   -5.142  -10.483 1.00 98.02  ? 463 PHE B CA  1 
ATOM   6668  C C   . PHE B 1 463 ? -0.872  -4.407  -9.470  1.00 90.35  ? 463 PHE B C   1 
ATOM   6669  O O   . PHE B 1 463 ? -1.457  -5.041  -8.602  1.00 120.85 ? 463 PHE B O   1 
ATOM   6670  C CB  . PHE B 1 463 ? 0.771   -4.248  -11.487 1.00 102.84 ? 463 PHE B CB  1 
ATOM   6671  C CG  . PHE B 1 463 ? 1.815   -3.347  -10.841 1.00 112.23 ? 463 PHE B CG  1 
ATOM   6672  C CD1 . PHE B 1 463 ? 2.941   -3.887  -10.232 1.00 115.86 ? 463 PHE B CD1 1 
ATOM   6673  C CD2 . PHE B 1 463 ? 1.649   -1.966  -10.804 1.00 117.26 ? 463 PHE B CD2 1 
ATOM   6674  C CE1 . PHE B 1 463 ? 3.876   -3.068  -9.610  1.00 111.78 ? 463 PHE B CE1 1 
ATOM   6675  C CE2 . PHE B 1 463 ? 2.588   -1.154  -10.179 1.00 112.03 ? 463 PHE B CE2 1 
ATOM   6676  C CZ  . PHE B 1 463 ? 3.698   -1.706  -9.589  1.00 110.50 ? 463 PHE B CZ  1 
ATOM   6677  N N   . ASN B 1 464 ? -0.973  -3.076  -9.599  1.00 64.62  ? 464 ASN B N   1 
ATOM   6678  C CA  . ASN B 1 464 ? -1.978  -2.264  -8.889  1.00 58.51  ? 464 ASN B CA  1 
ATOM   6679  C C   . ASN B 1 464 ? -1.740  -2.287  -7.372  1.00 46.05  ? 464 ASN B C   1 
ATOM   6680  O O   . ASN B 1 464 ? -1.161  -3.210  -6.822  1.00 43.22  ? 464 ASN B O   1 
ATOM   6681  C CB  . ASN B 1 464 ? -3.426  -2.644  -9.260  1.00 54.14  ? 464 ASN B CB  1 
ATOM   6682  C CG  . ASN B 1 464 ? -3.969  -3.798  -8.447  1.00 57.01  ? 464 ASN B CG  1 
ATOM   6683  O OD1 . ASN B 1 464 ? -4.280  -3.650  -7.258  1.00 66.46  ? 464 ASN B OD1 1 
ATOM   6684  N ND2 . ASN B 1 464 ? -4.111  -4.948  -9.073  1.00 64.74  ? 464 ASN B ND2 1 
ATOM   6685  N N   . GLY B 1 465 ? -2.271  -1.275  -6.712  1.00 43.39  ? 465 GLY B N   1 
ATOM   6686  C CA  . GLY B 1 465 ? -1.976  -1.015  -5.327  1.00 45.41  ? 465 GLY B CA  1 
ATOM   6687  C C   . GLY B 1 465 ? -2.489  -2.116  -4.438  1.00 47.37  ? 465 GLY B C   1 
ATOM   6688  O O   . GLY B 1 465 ? -1.811  -2.507  -3.509  1.00 53.28  ? 465 GLY B O   1 
ATOM   6689  N N   . ASP B 1 466 ? -3.709  -2.590  -4.722  1.00 51.44  ? 466 ASP B N   1 
ATOM   6690  C CA  . ASP B 1 466 ? -4.355  -3.597  -3.898  1.00 49.21  ? 466 ASP B CA  1 
ATOM   6691  C C   . ASP B 1 466 ? -3.435  -4.798  -3.758  1.00 43.42  ? 466 ASP B C   1 
ATOM   6692  O O   . ASP B 1 466 ? -3.196  -5.250  -2.646  1.00 44.93  ? 466 ASP B O   1 
ATOM   6693  C CB  . ASP B 1 466 ? -5.740  -3.952  -4.424  1.00 54.83  ? 466 ASP B CB  1 
ATOM   6694  C CG  . ASP B 1 466 ? -6.765  -2.812  -4.389  1.00 61.62  ? 466 ASP B CG  1 
ATOM   6695  O OD1 . ASP B 1 466 ? -6.766  -2.064  -3.400  1.00 60.99  ? 466 ASP B OD1 1 
ATOM   6696  O OD2 . ASP B 1 466 ? -7.578  -2.707  -5.346  1.00 70.39  ? 466 ASP B OD2 1 
ATOM   6697  N N   . TRP B 1 467 ? -2.908  -5.284  -4.897  1.00 41.95  ? 467 TRP B N   1 
ATOM   6698  C CA  . TRP B 1 467 ? -1.993  -6.425  -4.916  1.00 40.46  ? 467 TRP B CA  1 
ATOM   6699  C C   . TRP B 1 467 ? -0.686  -6.101  -4.166  1.00 39.20  ? 467 TRP B C   1 
ATOM   6700  O O   . TRP B 1 467 ? -0.222  -6.888  -3.370  1.00 45.79  ? 467 TRP B O   1 
ATOM   6701  C CB  . TRP B 1 467 ? -1.696  -6.852  -6.363  1.00 40.03  ? 467 TRP B CB  1 
ATOM   6702  C CG  . TRP B 1 467 ? -0.434  -7.662  -6.492  1.00 46.91  ? 467 TRP B CG  1 
ATOM   6703  C CD1 . TRP B 1 467 ? -0.295  -9.009  -6.295  1.00 48.60  ? 467 TRP B CD1 1 
ATOM   6704  C CD2 . TRP B 1 467 ? 0.887   -7.159  -6.777  1.00 46.50  ? 467 TRP B CD2 1 
ATOM   6705  N NE1 . TRP B 1 467 ? 1.008   -9.380  -6.468  1.00 54.59  ? 467 TRP B NE1 1 
ATOM   6706  C CE2 . TRP B 1 467 ? 1.761   -8.271  -6.758  1.00 50.25  ? 467 TRP B CE2 1 
ATOM   6707  C CE3 . TRP B 1 467 ? 1.410   -5.894  -7.056  1.00 42.35  ? 467 TRP B CE3 1 
ATOM   6708  C CZ2 . TRP B 1 467 ? 3.128   -8.147  -6.992  1.00 46.57  ? 467 TRP B CZ2 1 
ATOM   6709  C CZ3 . TRP B 1 467 ? 2.765   -5.770  -7.292  1.00 44.16  ? 467 TRP B CZ3 1 
ATOM   6710  C CH2 . TRP B 1 467 ? 3.611   -6.878  -7.253  1.00 46.66  ? 467 TRP B CH2 1 
ATOM   6711  N N   . ALA B 1 468 ? -0.113  -4.939  -4.431  1.00 39.74  ? 468 ALA B N   1 
ATOM   6712  C CA  . ALA B 1 468 ? 1.177   -4.576  -3.857  1.00 44.27  ? 468 ALA B CA  1 
ATOM   6713  C C   . ALA B 1 468 ? 1.078   -4.460  -2.339  1.00 42.95  ? 468 ALA B C   1 
ATOM   6714  O O   . ALA B 1 468 ? 1.969   -4.920  -1.614  1.00 40.39  ? 468 ALA B O   1 
ATOM   6715  C CB  . ALA B 1 468 ? 1.669   -3.286  -4.472  1.00 46.81  ? 468 ALA B CB  1 
ATOM   6716  N N   . ILE B 1 469 ? -0.005  -3.839  -1.869  1.00 41.36  ? 469 ILE B N   1 
ATOM   6717  C CA  . ILE B 1 469 ? -0.216  -3.633  -0.445  1.00 42.17  ? 469 ILE B CA  1 
ATOM   6718  C C   . ILE B 1 469 ? -0.402  -4.986  0.246   1.00 42.74  ? 469 ILE B C   1 
ATOM   6719  O O   . ILE B 1 469 ? 0.167   -5.230  1.313   1.00 51.24  ? 469 ILE B O   1 
ATOM   6720  C CB  . ILE B 1 469 ? -1.401  -2.686  -0.204  1.00 45.93  ? 469 ILE B CB  1 
ATOM   6721  C CG1 . ILE B 1 469 ? -1.063  -1.273  -0.644  1.00 44.29  ? 469 ILE B CG1 1 
ATOM   6722  C CG2 . ILE B 1 469 ? -1.853  -2.733  1.264   1.00 54.70  ? 469 ILE B CG2 1 
ATOM   6723  C CD1 . ILE B 1 469 ? -2.243  -0.338  -0.679  1.00 49.14  ? 469 ILE B CD1 1 
ATOM   6724  N N   . GLU B 1 470 ? -1.148  -5.875  -0.387  1.00 44.34  ? 470 GLU B N   1 
ATOM   6725  C CA  . GLU B 1 470 ? -1.349  -7.218  0.147   1.00 52.02  ? 470 GLU B CA  1 
ATOM   6726  C C   . GLU B 1 470 ? -0.004  -7.951  0.227   1.00 50.01  ? 470 GLU B C   1 
ATOM   6727  O O   . GLU B 1 470 ? 0.274   -8.615  1.213   1.00 51.96  ? 470 GLU B O   1 
ATOM   6728  C CB  . GLU B 1 470 ? -2.367  -8.001  -0.695  1.00 60.45  ? 470 GLU B CB  1 
ATOM   6729  C CG  . GLU B 1 470 ? -3.110  -9.095  0.087   1.00 66.49  ? 470 GLU B CG  1 
ATOM   6730  C CD  . GLU B 1 470 ? -3.641  -8.653  1.463   1.00 74.15  ? 470 GLU B CD  1 
ATOM   6731  O OE1 . GLU B 1 470 ? -4.407  -7.616  1.554   1.00 64.76  ? 470 GLU B OE1 1 
ATOM   6732  O OE2 . GLU B 1 470 ? -3.256  -9.324  2.461   1.00 70.49  ? 470 GLU B OE2 1 
ATOM   6733  N N   . GLU B 1 471 ? 0.835   -7.807  -0.818  1.00 46.34  ? 471 GLU B N   1 
ATOM   6734  C CA  . GLU B 1 471 ? 2.058   -8.598  -0.926  1.00 45.92  ? 471 GLU B CA  1 
ATOM   6735  C C   . GLU B 1 471 ? 3.103   -8.140  0.111   1.00 38.81  ? 471 GLU B C   1 
ATOM   6736  O O   . GLU B 1 471 ? 3.704   -8.975  0.775   1.00 36.72  ? 471 GLU B O   1 
ATOM   6737  C CB  . GLU B 1 471 ? 2.640   -8.525  -2.334  1.00 56.28  ? 471 GLU B CB  1 
ATOM   6738  C CG  . GLU B 1 471 ? 3.440   -9.767  -2.728  1.00 65.62  ? 471 GLU B CG  1 
ATOM   6739  C CD  . GLU B 1 471 ? 2.560   -10.963 -3.004  1.00 77.62  ? 471 GLU B CD  1 
ATOM   6740  O OE1 . GLU B 1 471 ? 2.012   -11.521 -2.038  1.00 86.83  ? 471 GLU B OE1 1 
ATOM   6741  O OE2 . GLU B 1 471 ? 2.391   -11.315 -4.182  1.00 91.01  ? 471 GLU B OE2 1 
ATOM   6742  N N   . PHE B 1 472 ? 3.331   -6.819  0.216   1.00 31.70  ? 472 PHE B N   1 
ATOM   6743  C CA  . PHE B 1 472 ? 4.514   -6.303  0.893   1.00 36.07  ? 472 PHE B CA  1 
ATOM   6744  C C   . PHE B 1 472 ? 4.160   -5.584  2.218   1.00 37.00  ? 472 PHE B C   1 
ATOM   6745  O O   . PHE B 1 472 ? 5.007   -4.885  2.776   1.00 34.99  ? 472 PHE B O   1 
ATOM   6746  C CB  . PHE B 1 472 ? 5.265   -5.345  -0.032  1.00 35.83  ? 472 PHE B CB  1 
ATOM   6747  C CG  . PHE B 1 472 ? 5.640   -5.937  -1.381  1.00 36.40  ? 472 PHE B CG  1 
ATOM   6748  C CD1 . PHE B 1 472 ? 6.558   -6.970  -1.474  1.00 36.34  ? 472 PHE B CD1 1 
ATOM   6749  C CD2 . PHE B 1 472 ? 5.118   -5.422  -2.555  1.00 38.71  ? 472 PHE B CD2 1 
ATOM   6750  C CE1 . PHE B 1 472 ? 6.913   -7.498  -2.708  1.00 35.97  ? 472 PHE B CE1 1 
ATOM   6751  C CE2 . PHE B 1 472 ? 5.465   -5.966  -3.782  1.00 38.02  ? 472 PHE B CE2 1 
ATOM   6752  C CZ  . PHE B 1 472 ? 6.364   -7.002  -3.851  1.00 34.84  ? 472 PHE B CZ  1 
ATOM   6753  N N   . THR B 1 473 ? 2.923   -5.754  2.712   1.00 39.23  ? 473 THR B N   1 
ATOM   6754  C CA  . THR B 1 473 ? 2.575   -5.343  4.081   1.00 40.22  ? 473 THR B CA  1 
ATOM   6755  C C   . THR B 1 473 ? 1.864   -6.494  4.760   1.00 43.84  ? 473 THR B C   1 
ATOM   6756  O O   . THR B 1 473 ? 1.435   -7.443  4.099   1.00 48.65  ? 473 THR B O   1 
ATOM   6757  C CB  . THR B 1 473 ? 1.712   -4.064  4.106   1.00 38.19  ? 473 THR B CB  1 
ATOM   6758  O OG1 . THR B 1 473 ? 0.387   -4.379  3.681   1.00 34.58  ? 473 THR B OG1 1 
ATOM   6759  C CG2 . THR B 1 473 ? 2.271   -2.959  3.235   1.00 39.92  ? 473 THR B CG2 1 
ATOM   6760  N N   . THR B 1 474 ? 1.749   -6.399  6.086   1.00 48.56  ? 474 THR B N   1 
ATOM   6761  C CA  . THR B 1 474 ? 1.079   -7.415  6.885   1.00 47.16  ? 474 THR B CA  1 
ATOM   6762  C C   . THR B 1 474 ? 0.247   -6.746  7.979   1.00 44.17  ? 474 THR B C   1 
ATOM   6763  O O   . THR B 1 474 ? 0.441   -5.575  8.311   1.00 42.29  ? 474 THR B O   1 
ATOM   6764  C CB  . THR B 1 474 ? 2.113   -8.390  7.472   1.00 52.42  ? 474 THR B CB  1 
ATOM   6765  O OG1 . THR B 1 474 ? 1.359   -9.310  8.256   1.00 60.27  ? 474 THR B OG1 1 
ATOM   6766  C CG2 . THR B 1 474 ? 3.166   -7.705  8.328   1.00 52.79  ? 474 THR B CG2 1 
ATOM   6767  N N   . ASP B 1 475 ? -0.667  -7.528  8.539   1.00 45.61  ? 475 ASP B N   1 
ATOM   6768  C CA  . ASP B 1 475 ? -1.573  -7.082  9.573   1.00 43.40  ? 475 ASP B CA  1 
ATOM   6769  C C   . ASP B 1 475 ? -1.027  -7.514  10.931  1.00 41.78  ? 475 ASP B C   1 
ATOM   6770  O O   . ASP B 1 475 ? -0.590  -8.660  11.095  1.00 44.64  ? 475 ASP B O   1 
ATOM   6771  C CB  . ASP B 1 475 ? -2.972  -7.641  9.339   1.00 48.56  ? 475 ASP B CB  1 
ATOM   6772  C CG  . ASP B 1 475 ? -3.925  -6.759  8.524   1.00 53.99  ? 475 ASP B CG  1 
ATOM   6773  O OD1 . ASP B 1 475 ? -3.727  -5.544  8.519   1.00 68.73  ? 475 ASP B OD1 1 
ATOM   6774  O OD2 . ASP B 1 475 ? -4.897  -7.298  7.957   1.00 62.23  ? 475 ASP B OD2 1 
ATOM   6775  N N   . HIS B 1 476 ? -1.049  -6.583  11.901  1.00 37.63  ? 476 HIS B N   1 
ATOM   6776  C CA  . HIS B 1 476 ? -0.734  -6.896  13.285  1.00 37.97  ? 476 HIS B CA  1 
ATOM   6777  C C   . HIS B 1 476 ? -1.937  -6.551  14.139  1.00 36.09  ? 476 HIS B C   1 
ATOM   6778  O O   . HIS B 1 476 ? -2.212  -5.359  14.404  1.00 28.94  ? 476 HIS B O   1 
ATOM   6779  C CB  . HIS B 1 476 ? 0.526   -6.153  13.758  1.00 40.06  ? 476 HIS B CB  1 
ATOM   6780  C CG  . HIS B 1 476 ? 1.056   -6.627  15.087  1.00 43.81  ? 476 HIS B CG  1 
ATOM   6781  N ND1 . HIS B 1 476 ? 2.253   -6.187  15.621  1.00 44.23  ? 476 HIS B ND1 1 
ATOM   6782  C CD2 . HIS B 1 476 ? 0.543   -7.498  15.999  1.00 43.69  ? 476 HIS B CD2 1 
ATOM   6783  C CE1 . HIS B 1 476 ? 2.467   -6.802  16.786  1.00 43.07  ? 476 HIS B CE1 1 
ATOM   6784  N NE2 . HIS B 1 476 ? 1.436   -7.595  17.037  1.00 40.86  ? 476 HIS B NE2 1 
ATOM   6785  N N   . TRP B 1 477 ? -2.664  -7.596  14.550  1.00 37.17  ? 477 TRP B N   1 
ATOM   6786  C CA  . TRP B 1 477 ? -3.844  -7.433  15.399  1.00 42.79  ? 477 TRP B CA  1 
ATOM   6787  C C   . TRP B 1 477 ? -3.404  -7.123  16.827  1.00 41.38  ? 477 TRP B C   1 
ATOM   6788  O O   . TRP B 1 477 ? -2.685  -7.917  17.452  1.00 41.35  ? 477 TRP B O   1 
ATOM   6789  C CB  . TRP B 1 477 ? -4.733  -8.691  15.352  1.00 42.34  ? 477 TRP B CB  1 
ATOM   6790  C CG  . TRP B 1 477 ? -5.494  -8.854  14.058  1.00 50.27  ? 477 TRP B CG  1 
ATOM   6791  C CD1 . TRP B 1 477 ? -4.988  -9.232  12.835  1.00 45.92  ? 477 TRP B CD1 1 
ATOM   6792  C CD2 . TRP B 1 477 ? -6.914  -8.660  13.862  1.00 48.82  ? 477 TRP B CD2 1 
ATOM   6793  N NE1 . TRP B 1 477 ? -5.986  -9.274  11.902  1.00 45.57  ? 477 TRP B NE1 1 
ATOM   6794  C CE2 . TRP B 1 477 ? -7.180  -8.928  12.497  1.00 50.71  ? 477 TRP B CE2 1 
ATOM   6795  C CE3 . TRP B 1 477 ? -7.974  -8.289  14.698  1.00 47.57  ? 477 TRP B CE3 1 
ATOM   6796  C CZ2 . TRP B 1 477 ? -8.468  -8.824  11.955  1.00 51.21  ? 477 TRP B CZ2 1 
ATOM   6797  C CZ3 . TRP B 1 477 ? -9.242  -8.181  14.161  1.00 51.17  ? 477 TRP B CZ3 1 
ATOM   6798  C CH2 . TRP B 1 477 ? -9.483  -8.427  12.805  1.00 46.26  ? 477 TRP B CH2 1 
ATOM   6799  N N   . ILE B 1 478 ? -3.841  -5.970  17.332  1.00 37.18  ? 478 ILE B N   1 
ATOM   6800  C CA  . ILE B 1 478 ? -3.606  -5.595  18.717  1.00 38.48  ? 478 ILE B CA  1 
ATOM   6801  C C   . ILE B 1 478 ? -4.939  -5.308  19.381  1.00 37.39  ? 478 ILE B C   1 
ATOM   6802  O O   . ILE B 1 478 ? -5.551  -4.274  19.126  1.00 40.07  ? 478 ILE B O   1 
ATOM   6803  C CB  . ILE B 1 478 ? -2.661  -4.387  18.811  1.00 44.22  ? 478 ILE B CB  1 
ATOM   6804  C CG1 . ILE B 1 478 ? -1.364  -4.651  18.072  1.00 46.58  ? 478 ILE B CG1 1 
ATOM   6805  C CG2 . ILE B 1 478 ? -2.411  -3.999  20.278  1.00 42.26  ? 478 ILE B CG2 1 
ATOM   6806  C CD1 . ILE B 1 478 ? -0.314  -3.595  18.274  1.00 48.38  ? 478 ILE B CD1 1 
ATOM   6807  N N   . SER B 1 479 ? -5.366  -6.230  20.250  1.00 39.47  ? 479 SER B N   1 
ATOM   6808  C CA  . SER B 1 479 ? -6.595  -6.074  21.020  1.00 40.70  ? 479 SER B CA  1 
ATOM   6809  C C   . SER B 1 479 ? -6.279  -5.465  22.386  1.00 37.05  ? 479 SER B C   1 
ATOM   6810  O O   . SER B 1 479 ? -5.427  -5.954  23.084  1.00 40.38  ? 479 SER B O   1 
ATOM   6811  C CB  . SER B 1 479 ? -7.312  -7.390  21.164  1.00 44.28  ? 479 SER B CB  1 
ATOM   6812  O OG  . SER B 1 479 ? -6.796  -8.136  22.260  1.00 57.04  ? 479 SER B OG  1 
ATOM   6813  N N   . VAL B 1 480 ? -6.974  -4.378  22.732  1.00 39.45  ? 480 VAL B N   1 
ATOM   6814  C CA  . VAL B 1 480 ? -6.752  -3.684  23.987  1.00 39.56  ? 480 VAL B CA  1 
ATOM   6815  C C   . VAL B 1 480 ? -7.964  -3.865  24.897  1.00 39.53  ? 480 VAL B C   1 
ATOM   6816  O O   . VAL B 1 480 ? -9.084  -3.483  24.539  1.00 37.27  ? 480 VAL B O   1 
ATOM   6817  C CB  . VAL B 1 480 ? -6.467  -2.208  23.751  1.00 39.08  ? 480 VAL B CB  1 
ATOM   6818  C CG1 . VAL B 1 480 ? -5.870  -1.560  24.987  1.00 39.95  ? 480 VAL B CG1 1 
ATOM   6819  C CG2 . VAL B 1 480 ? -5.555  -2.015  22.555  1.00 42.01  ? 480 VAL B CG2 1 
ATOM   6820  N N   . GLN B 1 481 ? -7.708  -4.420  26.093  1.00 42.55  ? 481 GLN B N   1 
ATOM   6821  C CA  . GLN B 1 481 ? -8.728  -4.596  27.134  1.00 45.35  ? 481 GLN B CA  1 
ATOM   6822  C C   . GLN B 1 481 ? -8.637  -3.433  28.116  1.00 42.36  ? 481 GLN B C   1 
ATOM   6823  O O   . GLN B 1 481 ? -7.595  -3.220  28.729  1.00 47.65  ? 481 GLN B O   1 
ATOM   6824  C CB  . GLN B 1 481 ? -8.501  -5.931  27.844  1.00 41.96  ? 481 GLN B CB  1 
ATOM   6825  C CG  . GLN B 1 481 ? -9.508  -6.243  28.936  1.00 44.06  ? 481 GLN B CG  1 
ATOM   6826  C CD  . GLN B 1 481 ? -10.929 -6.397  28.425  1.00 48.30  ? 481 GLN B CD  1 
ATOM   6827  O OE1 . GLN B 1 481 ? -11.844 -5.685  28.849  1.00 46.81  ? 481 GLN B OE1 1 
ATOM   6828  N NE2 . GLN B 1 481 ? -11.124 -7.321  27.495  1.00 47.76  ? 481 GLN B NE2 1 
ATOM   6829  N N   . HIS B 1 482 ? -9.710  -2.658  28.214  1.00 40.81  ? 482 HIS B N   1 
ATOM   6830  C CA  . HIS B 1 482 ? -9.730  -1.480  29.063  1.00 43.75  ? 482 HIS B CA  1 
ATOM   6831  C C   . HIS B 1 482 ? -10.368 -1.796  30.427  1.00 41.40  ? 482 HIS B C   1 
ATOM   6832  O O   . HIS B 1 482 ? -10.353 -0.951  31.300  1.00 43.11  ? 482 HIS B O   1 
ATOM   6833  C CB  . HIS B 1 482 ? -10.484 -0.327  28.387  1.00 41.89  ? 482 HIS B CB  1 
ATOM   6834  C CG  . HIS B 1 482 ? -9.951  0.065   27.060  1.00 44.29  ? 482 HIS B CG  1 
ATOM   6835  N ND1 . HIS B 1 482 ? -9.225  1.225   26.853  1.00 46.03  ? 482 HIS B ND1 1 
ATOM   6836  C CD2 . HIS B 1 482 ? -10.091 -0.507  25.851  1.00 51.60  ? 482 HIS B CD2 1 
ATOM   6837  C CE1 . HIS B 1 482 ? -8.902  1.323   25.560  1.00 49.48  ? 482 HIS B CE1 1 
ATOM   6838  N NE2 . HIS B 1 482 ? -9.419  0.286   24.926  1.00 53.30  ? 482 HIS B NE2 1 
ATOM   6839  N N   . ALA B 1 483 ? -10.962 -2.998  30.585  1.00 44.09  ? 483 ALA B N   1 
ATOM   6840  C CA  . ALA B 1 483 ? -11.781 -3.303  31.772  1.00 54.04  ? 483 ALA B CA  1 
ATOM   6841  C C   . ALA B 1 483 ? -11.440 -4.689  32.341  1.00 51.56  ? 483 ALA B C   1 
ATOM   6842  O O   . ALA B 1 483 ? -11.152 -5.605  31.605  1.00 54.91  ? 483 ALA B O   1 
ATOM   6843  C CB  . ALA B 1 483 ? -13.255 -3.212  31.424  1.00 63.32  ? 483 ALA B CB  1 
ATOM   6844  N N   . PRO B 1 484 ? -11.540 -4.938  33.676  1.00 57.04  ? 484 PRO B N   1 
ATOM   6845  C CA  . PRO B 1 484 ? -11.170 -6.234  34.236  1.00 59.45  ? 484 PRO B CA  1 
ATOM   6846  C C   . PRO B 1 484 ? -11.982 -7.431  33.737  1.00 58.40  ? 484 PRO B C   1 
ATOM   6847  O O   . PRO B 1 484 ? -13.153 -7.249  33.355  1.00 59.83  ? 484 PRO B O   1 
ATOM   6848  C CB  . PRO B 1 484 ? -11.344 -6.026  35.752  1.00 62.78  ? 484 PRO B CB  1 
ATOM   6849  C CG  . PRO B 1 484 ? -11.198 -4.541  35.935  1.00 61.95  ? 484 PRO B CG  1 
ATOM   6850  C CD  . PRO B 1 484 ? -11.978 -4.021  34.751  1.00 62.19  ? 484 PRO B CD  1 
ATOM   6851  N N   . ARG B 1 485 ? -11.451 -8.712  33.773  1.00 58.16  ? 485 ARG B N   1 
ATOM   6852  C CA  . ARG B 1 485 ? -12.114 -9.931  33.237  1.00 59.93  ? 485 ARG B CA  1 
ATOM   6853  C C   . ARG B 1 485 ? -12.267 -11.018 34.313  1.00 62.94  ? 485 ARG B C   1 
ATOM   6854  O O   . ARG B 1 485 ? -11.283 -11.275 35.032  1.00 65.34  ? 485 ARG B O   1 
ATOM   6855  C CB  . ARG B 1 485 ? -11.328 -10.483 32.046  1.00 50.00  ? 485 ARG B CB  1 
ATOM   6856  C CG  . ARG B 1 485 ? -11.335 -9.577  30.825  1.00 50.00  ? 485 ARG B CG  1 
ATOM   6857  C CD  . ARG B 1 485 ? -11.533 -10.311 29.509  1.00 50.00  ? 485 ARG B CD  1 
ATOM   6858  N NE  . ARG B 1 485 ? -11.862 -11.719 29.710  1.00 50.00  ? 485 ARG B NE  1 
ATOM   6859  C CZ  . ARG B 1 485 ? -12.611 -12.435 28.884  1.00 50.00  ? 485 ARG B CZ  1 
ATOM   6860  N NH1 . ARG B 1 485 ? -13.111 -11.878 27.788  1.00 50.00  ? 485 ARG B NH1 1 
ATOM   6861  N NH2 . ARG B 1 485 ? -12.860 -13.711 29.147  1.00 50.00  ? 485 ARG B NH2 1 
ATOM   6862  N N   . GLN B 1 486 ? -13.388 -11.543 34.412  1.00 72.32  ? 486 GLN B N   1 
ATOM   6863  C CA  . GLN B 1 486 ? -13.641 -12.645 35.381  1.00 71.04  ? 486 GLN B CA  1 
ATOM   6864  C C   . GLN B 1 486 ? -12.761 -13.870 35.068  1.00 70.39  ? 486 GLN B C   1 
ATOM   6865  O O   . GLN B 1 486 ? -12.269 -14.490 36.034  1.00 80.13  ? 486 GLN B O   1 
ATOM   6866  C CB  . GLN B 1 486 ? -15.123 -13.012 35.350  1.00 79.27  ? 486 GLN B CB  1 
ATOM   6867  C CG  . GLN B 1 486 ? -15.535 -14.034 36.402  1.00 87.22  ? 486 GLN B CG  1 
ATOM   6868  C CD  . GLN B 1 486 ? -15.239 -13.583 37.815  1.00 88.17  ? 486 GLN B CD  1 
ATOM   6869  O OE1 . GLN B 1 486 ? -14.355 -14.118 38.492  1.00 94.45  ? 486 GLN B OE1 1 
ATOM   6870  N NE2 . GLN B 1 486 ? -15.982 -12.586 38.273  1.00 91.60  ? 486 GLN B NE2 1 
ATOM   6871  N N   . TYR B 1 487 ? -12.572 -14.205 33.788  1.00 65.17  ? 487 TYR B N   1 
ATOM   6872  C CA  . TYR B 1 487 ? -11.788 -15.413 33.384  1.00 67.32  ? 487 TYR B CA  1 
ATOM   6873  C C   . TYR B 1 487 ? -12.348 -16.711 33.989  1.00 71.35  ? 487 TYR B C   1 
ATOM   6874  O O   . TYR B 1 487 ? -11.517 -17.523 34.441  1.00 74.14  ? 487 TYR B O   1 
ATOM   6875  C CB  . TYR B 1 487 ? -10.302 -15.339 33.751  1.00 62.33  ? 487 TYR B CB  1 
ATOM   6876  C CG  . TYR B 1 487 ? -9.528  -14.244 33.037  1.00 57.97  ? 487 TYR B CG  1 
ATOM   6877  C CD1 . TYR B 1 487 ? -8.671  -13.407 33.735  1.00 50.97  ? 487 TYR B CD1 1 
ATOM   6878  C CD2 . TYR B 1 487 ? -9.661  -14.051 31.669  1.00 62.95  ? 487 TYR B CD2 1 
ATOM   6879  C CE1 . TYR B 1 487 ? -7.961  -12.411 33.092  1.00 53.32  ? 487 TYR B CE1 1 
ATOM   6880  C CE2 . TYR B 1 487 ? -8.959  -13.054 31.016  1.00 54.13  ? 487 TYR B CE2 1 
ATOM   6881  C CZ  . TYR B 1 487 ? -8.107  -12.232 31.729  1.00 56.39  ? 487 TYR B CZ  1 
ATOM   6882  O OH  . TYR B 1 487 ? -7.411  -11.246 31.097  1.00 56.35  ? 487 TYR B OH  1 
ATOM   6883  N N   . PRO B 1 488 ? -13.677 -16.961 34.031  1.00 81.43  ? 488 PRO B N   1 
ATOM   6884  C CA  . PRO B 1 488 ? -14.230 -18.149 34.666  1.00 79.45  ? 488 PRO B CA  1 
ATOM   6885  C C   . PRO B 1 488 ? -13.225 -19.195 35.121  1.00 75.15  ? 488 PRO B C   1 
ATOM   6886  O O   . PRO B 1 488 ? -13.457 -20.374 34.788  1.00 78.48  ? 488 PRO B O   1 
ATOM   6887  C CB  . PRO B 1 488 ? -15.058 -18.644 33.475  1.00 84.26  ? 488 PRO B CB  1 
ATOM   6888  C CG  . PRO B 1 488 ? -15.665 -17.376 32.912  1.00 83.78  ? 488 PRO B CG  1 
ATOM   6889  C CD  . PRO B 1 488 ? -14.720 -16.250 33.310  1.00 80.21  ? 488 PRO B CD  1 
ATOM   6890  N N   . SER C 1 2   ? -32.914 -35.113 13.828  1.00 119.51 ? 2   SER C N   1 
ATOM   6891  C CA  . SER C 1 2   ? -33.543 -36.345 14.377  1.00 110.99 ? 2   SER C CA  1 
ATOM   6892  C C   . SER C 1 2   ? -33.392 -36.366 15.894  1.00 113.33 ? 2   SER C C   1 
ATOM   6893  O O   . SER C 1 2   ? -32.837 -35.441 16.480  1.00 98.25  ? 2   SER C O   1 
ATOM   6894  C CB  . SER C 1 2   ? -32.947 -37.594 13.744  1.00 104.83 ? 2   SER C CB  1 
ATOM   6895  O OG  . SER C 1 2   ? -33.340 -38.767 14.446  1.00 101.60 ? 2   SER C OG  1 
ATOM   6896  N N   . ASP C 1 3   ? -33.870 -37.453 16.508  1.00 117.88 ? 3   ASP C N   1 
ATOM   6897  C CA  . ASP C 1 3   ? -33.833 -37.627 17.957  1.00 119.16 ? 3   ASP C CA  1 
ATOM   6898  C C   . ASP C 1 3   ? -32.642 -38.516 18.348  1.00 106.80 ? 3   ASP C C   1 
ATOM   6899  O O   . ASP C 1 3   ? -31.928 -38.221 19.315  1.00 99.11  ? 3   ASP C O   1 
ATOM   6900  C CB  . ASP C 1 3   ? -35.146 -38.207 18.463  1.00 123.41 ? 3   ASP C CB  1 
ATOM   6901  C CG  . ASP C 1 3   ? -35.757 -39.283 17.577  1.00 121.61 ? 3   ASP C CG  1 
ATOM   6902  O OD1 . ASP C 1 3   ? -35.177 -39.552 16.502  1.00 127.67 ? 3   ASP C OD1 1 
ATOM   6903  O OD2 . ASP C 1 3   ? -36.818 -39.825 17.956  1.00 117.97 ? 3   ASP C OD2 1 
ATOM   6904  N N   . SER C 1 4   ? -32.456 -39.623 17.608  1.00 88.89  ? 4   SER C N   1 
ATOM   6905  C CA  . SER C 1 4   ? -31.457 -40.623 17.967  1.00 74.84  ? 4   SER C CA  1 
ATOM   6906  C C   . SER C 1 4   ? -30.056 -40.149 17.557  1.00 62.02  ? 4   SER C C   1 
ATOM   6907  O O   . SER C 1 4   ? -29.886 -39.464 16.552  1.00 61.08  ? 4   SER C O   1 
ATOM   6908  C CB  . SER C 1 4   ? -31.788 -41.973 17.367  1.00 71.21  ? 4   SER C CB  1 
ATOM   6909  O OG  . SER C 1 4   ? -32.100 -41.853 15.991  1.00 80.99  ? 4   SER C OG  1 
ATOM   6910  N N   . ARG C 1 5   ? -29.064 -40.538 18.358  1.00 56.18  ? 5   ARG C N   1 
ATOM   6911  C CA  . ARG C 1 5   ? -27.669 -40.221 18.108  1.00 54.37  ? 5   ARG C CA  1 
ATOM   6912  C C   . ARG C 1 5   ? -27.187 -40.948 16.847  1.00 54.51  ? 5   ARG C C   1 
ATOM   6913  O O   . ARG C 1 5   ? -27.740 -41.978 16.464  1.00 58.26  ? 5   ARG C O   1 
ATOM   6914  C CB  . ARG C 1 5   ? -26.840 -40.565 19.360  1.00 56.16  ? 5   ARG C CB  1 
ATOM   6915  C CG  . ARG C 1 5   ? -26.716 -39.378 20.311  1.00 63.94  ? 5   ARG C CG  1 
ATOM   6916  C CD  . ARG C 1 5   ? -26.575 -39.762 21.805  1.00 62.75  ? 5   ARG C CD  1 
ATOM   6917  N NE  . ARG C 1 5   ? -25.180 -39.762 22.265  1.00 69.45  ? 5   ARG C NE  1 
ATOM   6918  C CZ  . ARG C 1 5   ? -24.668 -39.079 23.331  1.00 72.28  ? 5   ARG C CZ  1 
ATOM   6919  N NH1 . ARG C 1 5   ? -25.403 -38.208 23.999  1.00 72.25  ? 5   ARG C NH1 1 
ATOM   6920  N NH2 . ARG C 1 5   ? -23.408 -39.275 23.696  1.00 78.58  ? 5   ARG C NH2 1 
ATOM   6921  N N   . TYR C 1 6   ? -26.174 -40.366 16.181  1.00 53.73  ? 6   TYR C N   1 
ATOM   6922  C CA  . TYR C 1 6   ? -25.563 -40.978 15.001  1.00 51.72  ? 6   TYR C CA  1 
ATOM   6923  C C   . TYR C 1 6   ? -24.987 -42.345 15.392  1.00 51.70  ? 6   TYR C C   1 
ATOM   6924  O O   . TYR C 1 6   ? -24.401 -42.485 16.466  1.00 47.98  ? 6   TYR C O   1 
ATOM   6925  C CB  . TYR C 1 6   ? -24.424 -40.108 14.451  1.00 50.81  ? 6   TYR C CB  1 
ATOM   6926  C CG  . TYR C 1 6   ? -24.796 -38.752 13.857  1.00 52.64  ? 6   TYR C CG  1 
ATOM   6927  C CD1 . TYR C 1 6   ? -25.816 -38.622 12.914  1.00 52.19  ? 6   TYR C CD1 1 
ATOM   6928  C CD2 . TYR C 1 6   ? -24.074 -37.607 14.189  1.00 49.21  ? 6   TYR C CD2 1 
ATOM   6929  C CE1 . TYR C 1 6   ? -26.122 -37.392 12.341  1.00 46.28  ? 6   TYR C CE1 1 
ATOM   6930  C CE2 . TYR C 1 6   ? -24.355 -36.378 13.607  1.00 50.84  ? 6   TYR C CE2 1 
ATOM   6931  C CZ  . TYR C 1 6   ? -25.388 -36.267 12.692  1.00 50.01  ? 6   TYR C CZ  1 
ATOM   6932  O OH  . TYR C 1 6   ? -25.670 -35.043 12.148  1.00 49.90  ? 6   TYR C OH  1 
ATOM   6933  N N   . THR C 1 7   ? -25.112 -43.333 14.495  1.00 50.74  ? 7   THR C N   1 
ATOM   6934  C CA  . THR C 1 7   ? -24.462 -44.631 14.691  1.00 57.84  ? 7   THR C CA  1 
ATOM   6935  C C   . THR C 1 7   ? -23.602 -44.958 13.470  1.00 59.17  ? 7   THR C C   1 
ATOM   6936  O O   . THR C 1 7   ? -23.688 -44.280 12.446  1.00 54.40  ? 7   THR C O   1 
ATOM   6937  C CB  . THR C 1 7   ? -25.506 -45.721 14.947  1.00 57.28  ? 7   THR C CB  1 
ATOM   6938  O OG1 . THR C 1 7   ? -26.336 -45.800 13.789  1.00 53.13  ? 7   THR C OG1 1 
ATOM   6939  C CG2 . THR C 1 7   ? -26.358 -45.423 16.157  1.00 58.16  ? 7   THR C CG2 1 
ATOM   6940  N N   . ASP C 1 8   ? -22.779 -46.018 13.605  1.00 58.09  ? 8   ASP C N   1 
ATOM   6941  C CA  . ASP C 1 8   ? -21.897 -46.475 12.541  1.00 59.62  ? 8   ASP C CA  1 
ATOM   6942  C C   . ASP C 1 8   ? -20.920 -45.359 12.151  1.00 50.21  ? 8   ASP C C   1 
ATOM   6943  O O   . ASP C 1 8   ? -20.660 -45.156 10.972  1.00 50.93  ? 8   ASP C O   1 
ATOM   6944  C CB  . ASP C 1 8   ? -22.693 -46.961 11.331  1.00 65.17  ? 8   ASP C CB  1 
ATOM   6945  C CG  . ASP C 1 8   ? -23.713 -48.045 11.626  1.00 71.56  ? 8   ASP C CG  1 
ATOM   6946  O OD1 . ASP C 1 8   ? -23.295 -49.195 11.828  1.00 75.41  ? 8   ASP C OD1 1 
ATOM   6947  O OD2 . ASP C 1 8   ? -24.912 -47.718 11.702  1.00 76.42  ? 8   ASP C OD2 1 
ATOM   6948  N N   . LEU C 1 9   ? -20.361 -44.663 13.150  1.00 46.05  ? 9   LEU C N   1 
ATOM   6949  C CA  . LEU C 1 9   ? -19.472 -43.531 12.888  1.00 54.09  ? 9   LEU C CA  1 
ATOM   6950  C C   . LEU C 1 9   ? -18.188 -43.998 12.197  1.00 51.56  ? 9   LEU C C   1 
ATOM   6951  O O   . LEU C 1 9   ? -17.438 -43.183 11.697  1.00 52.68  ? 9   LEU C O   1 
ATOM   6952  C CB  . LEU C 1 9   ? -19.151 -42.762 14.168  1.00 56.51  ? 9   LEU C CB  1 
ATOM   6953  C CG  . LEU C 1 9   ? -20.081 -41.589 14.494  1.00 57.83  ? 9   LEU C CG  1 
ATOM   6954  C CD1 . LEU C 1 9   ? -20.276 -40.672 13.281  1.00 57.94  ? 9   LEU C CD1 1 
ATOM   6955  C CD2 . LEU C 1 9   ? -21.406 -42.096 14.993  1.00 60.77  ? 9   LEU C CD2 1 
ATOM   6956  N N   . GLY C 1 10  ? -17.964 -45.307 12.154  1.00 52.39  ? 10  GLY C N   1 
ATOM   6957  C CA  . GLY C 1 10  ? -16.774 -45.873 11.525  1.00 51.67  ? 10  GLY C CA  1 
ATOM   6958  C C   . GLY C 1 10  ? -16.843 -45.865 9.984   1.00 45.16  ? 10  GLY C C   1 
ATOM   6959  O O   . GLY C 1 10  ? -15.815 -46.021 9.314   1.00 45.42  ? 10  GLY C O   1 
ATOM   6960  N N   . LEU C 1 11  ? -18.040 -45.701 9.421   1.00 41.48  ? 11  LEU C N   1 
ATOM   6961  C CA  . LEU C 1 11  ? -18.160 -45.601 7.965   1.00 42.29  ? 11  LEU C CA  1 
ATOM   6962  C C   . LEU C 1 11  ? -17.482 -44.300 7.486   1.00 41.68  ? 11  LEU C C   1 
ATOM   6963  O O   . LEU C 1 11  ? -17.619 -43.253 8.113   1.00 38.48  ? 11  LEU C O   1 
ATOM   6964  C CB  . LEU C 1 11  ? -19.617 -45.655 7.536   1.00 40.40  ? 11  LEU C CB  1 
ATOM   6965  C CG  . LEU C 1 11  ? -20.376 -46.940 7.870   1.00 42.53  ? 11  LEU C CG  1 
ATOM   6966  C CD1 . LEU C 1 11  ? -21.824 -46.741 7.593   1.00 46.23  ? 11  LEU C CD1 1 
ATOM   6967  C CD2 . LEU C 1 11  ? -19.877 -48.137 7.109   1.00 46.02  ? 11  LEU C CD2 1 
ATOM   6968  N N   . GLN C 1 12  ? -16.739 -44.396 6.380   1.00 39.34  ? 12  GLN C N   1 
ATOM   6969  C CA  . GLN C 1 12  ? -16.046 -43.247 5.807   1.00 40.54  ? 12  GLN C CA  1 
ATOM   6970  C C   . GLN C 1 12  ? -16.844 -42.701 4.619   1.00 38.28  ? 12  GLN C C   1 
ATOM   6971  O O   . GLN C 1 12  ? -17.279 -43.445 3.755   1.00 36.95  ? 12  GLN C O   1 
ATOM   6972  C CB  . GLN C 1 12  ? -14.636 -43.605 5.333   1.00 41.69  ? 12  GLN C CB  1 
ATOM   6973  C CG  . GLN C 1 12  ? -13.602 -43.687 6.447   1.00 43.84  ? 12  GLN C CG  1 
ATOM   6974  C CD  . GLN C 1 12  ? -12.219 -44.017 5.931   1.00 47.08  ? 12  GLN C CD  1 
ATOM   6975  O OE1 . GLN C 1 12  ? -11.523 -43.167 5.355   1.00 47.23  ? 12  GLN C OE1 1 
ATOM   6976  N NE2 . GLN C 1 12  ? -11.809 -45.266 6.114   1.00 47.54  ? 12  GLN C NE2 1 
ATOM   6977  N N   . PRO C 1 13  ? -17.052 -41.381 4.540   1.00 36.62  ? 13  PRO C N   1 
ATOM   6978  C CA  . PRO C 1 13  ? -17.629 -40.787 3.352   1.00 36.36  ? 13  PRO C CA  1 
ATOM   6979  C C   . PRO C 1 13  ? -16.599 -40.725 2.227   1.00 39.77  ? 13  PRO C C   1 
ATOM   6980  O O   . PRO C 1 13  ? -15.731 -39.859 2.235   1.00 42.20  ? 13  PRO C O   1 
ATOM   6981  C CB  . PRO C 1 13  ? -18.073 -39.380 3.845   1.00 37.78  ? 13  PRO C CB  1 
ATOM   6982  C CG  . PRO C 1 13  ? -17.098 -39.045 4.971   1.00 37.25  ? 13  PRO C CG  1 
ATOM   6983  C CD  . PRO C 1 13  ? -16.729 -40.399 5.593   1.00 37.78  ? 13  PRO C CD  1 
ATOM   6984  N N   . LEU C 1 14  ? -16.690 -41.666 1.269   1.00 42.03  ? 14  LEU C N   1 
ATOM   6985  C CA  . LEU C 1 14  ? -15.706 -41.755 0.178   1.00 43.17  ? 14  LEU C CA  1 
ATOM   6986  C C   . LEU C 1 14  ? -16.425 -41.660 -1.164  1.00 39.90  ? 14  LEU C C   1 
ATOM   6987  O O   . LEU C 1 14  ? -17.222 -42.524 -1.499  1.00 44.24  ? 14  LEU C O   1 
ATOM   6988  C CB  . LEU C 1 14  ? -14.890 -43.047 0.269   1.00 44.56  ? 14  LEU C CB  1 
ATOM   6989  C CG  . LEU C 1 14  ? -13.968 -43.179 1.486   1.00 43.43  ? 14  LEU C CG  1 
ATOM   6990  C CD1 . LEU C 1 14  ? -13.603 -44.642 1.723   1.00 42.56  ? 14  LEU C CD1 1 
ATOM   6991  C CD2 . LEU C 1 14  ? -12.721 -42.340 1.343   1.00 39.14  ? 14  LEU C CD2 1 
ATOM   6992  N N   . ALA C 1 15  ? -16.124 -40.594 -1.914  1.00 36.76  ? 15  ALA C N   1 
ATOM   6993  C CA  . ALA C 1 15  ? -16.643 -40.388 -3.270  1.00 37.56  ? 15  ALA C CA  1 
ATOM   6994  C C   . ALA C 1 15  ? -18.150 -40.609 -3.312  1.00 41.41  ? 15  ALA C C   1 
ATOM   6995  O O   . ALA C 1 15  ? -18.659 -41.290 -4.201  1.00 46.46  ? 15  ALA C O   1 
ATOM   6996  C CB  . ALA C 1 15  ? -15.932 -41.280 -4.234  1.00 37.05  ? 15  ALA C CB  1 
ATOM   6997  N N   . GLY C 1 16  ? -18.857 -39.982 -2.374  1.00 41.95  ? 16  GLY C N   1 
ATOM   6998  C CA  . GLY C 1 16  ? -20.302 -39.874 -2.450  1.00 45.63  ? 16  GLY C CA  1 
ATOM   6999  C C   . GLY C 1 16  ? -21.010 -41.067 -1.809  1.00 41.86  ? 16  GLY C C   1 
ATOM   7000  O O   . GLY C 1 16  ? -22.226 -41.166 -1.882  1.00 41.98  ? 16  GLY C O   1 
ATOM   7001  N N   . GLU C 1 17  ? -20.246 -41.918 -1.124  1.00 43.88  ? 17  GLU C N   1 
ATOM   7002  C CA  . GLU C 1 17  ? -20.773 -43.157 -0.547  1.00 48.35  ? 17  GLU C CA  1 
ATOM   7003  C C   . GLU C 1 17  ? -20.190 -43.323 0.851   1.00 45.29  ? 17  GLU C C   1 
ATOM   7004  O O   . GLU C 1 17  ? -19.054 -42.941 1.094   1.00 59.57  ? 17  GLU C O   1 
ATOM   7005  C CB  . GLU C 1 17  ? -20.438 -44.277 -1.539  1.00 53.98  ? 17  GLU C CB  1 
ATOM   7006  C CG  . GLU C 1 17  ? -20.481 -45.690 -0.974  1.00 71.49  ? 17  GLU C CG  1 
ATOM   7007  C CD  . GLU C 1 17  ? -20.112 -46.761 -2.034  1.00 83.28  ? 17  GLU C CD  1 
ATOM   7008  O OE1 . GLU C 1 17  ? -19.782 -46.376 -3.195  1.00 71.07  ? 17  GLU C OE1 1 
ATOM   7009  O OE2 . GLU C 1 17  ? -20.133 -47.977 -1.696  1.00 82.52  ? 17  GLU C OE2 1 
ATOM   7010  N N   . TRP C 1 18  ? -21.001 -43.820 1.781   1.00 42.16  ? 18  TRP C N   1 
ATOM   7011  C CA  . TRP C 1 18  ? -20.523 -44.154 3.123   1.00 45.21  ? 18  TRP C CA  1 
ATOM   7012  C C   . TRP C 1 18  ? -20.157 -45.636 3.169   1.00 44.62  ? 18  TRP C C   1 
ATOM   7013  O O   . TRP C 1 18  ? -21.026 -46.484 3.150   1.00 43.51  ? 18  TRP C O   1 
ATOM   7014  C CB  . TRP C 1 18  ? -21.581 -43.807 4.199   1.00 43.78  ? 18  TRP C CB  1 
ATOM   7015  C CG  . TRP C 1 18  ? -21.844 -42.321 4.364   1.00 48.06  ? 18  TRP C CG  1 
ATOM   7016  C CD1 . TRP C 1 18  ? -22.708 -41.552 3.638   1.00 50.01  ? 18  TRP C CD1 1 
ATOM   7017  C CD2 . TRP C 1 18  ? -21.230 -41.430 5.310   1.00 44.93  ? 18  TRP C CD2 1 
ATOM   7018  N NE1 . TRP C 1 18  ? -22.649 -40.250 4.045   1.00 49.73  ? 18  TRP C NE1 1 
ATOM   7019  C CE2 . TRP C 1 18  ? -21.768 -40.141 5.075   1.00 47.01  ? 18  TRP C CE2 1 
ATOM   7020  C CE3 . TRP C 1 18  ? -20.287 -41.591 6.325   1.00 52.38  ? 18  TRP C CE3 1 
ATOM   7021  C CZ2 . TRP C 1 18  ? -21.400 -39.029 5.824   1.00 46.24  ? 18  TRP C CZ2 1 
ATOM   7022  C CZ3 . TRP C 1 18  ? -19.924 -40.493 7.075   1.00 51.82  ? 18  TRP C CZ3 1 
ATOM   7023  C CH2 . TRP C 1 18  ? -20.473 -39.227 6.823   1.00 52.24  ? 18  TRP C CH2 1 
ATOM   7024  N N   . ARG C 1 19  ? -18.860 -45.938 3.222   1.00 47.61  ? 19  ARG C N   1 
ATOM   7025  C CA  . ARG C 1 19  ? -18.418 -47.329 3.173   1.00 51.76  ? 19  ARG C CA  1 
ATOM   7026  C C   . ARG C 1 19  ? -17.149 -47.522 3.993   1.00 49.47  ? 19  ARG C C   1 
ATOM   7027  O O   . ARG C 1 19  ? -16.567 -46.567 4.503   1.00 49.68  ? 19  ARG C O   1 
ATOM   7028  C CB  . ARG C 1 19  ? -18.194 -47.785 1.725   1.00 47.81  ? 19  ARG C CB  1 
ATOM   7029  C CG  . ARG C 1 19  ? -17.238 -46.916 0.930   1.00 45.23  ? 19  ARG C CG  1 
ATOM   7030  C CD  . ARG C 1 19  ? -16.795 -47.594 -0.347  1.00 41.71  ? 19  ARG C CD  1 
ATOM   7031  N NE  . ARG C 1 19  ? -15.918 -46.751 -1.166  1.00 39.96  ? 19  ARG C NE  1 
ATOM   7032  C CZ  . ARG C 1 19  ? -14.600 -46.857 -1.221  1.00 41.57  ? 19  ARG C CZ  1 
ATOM   7033  N NH1 . ARG C 1 19  ? -13.959 -47.744 -0.460  1.00 40.86  ? 19  ARG C NH1 1 
ATOM   7034  N NH2 . ARG C 1 19  ? -13.914 -46.059 -2.016  1.00 42.35  ? 19  ARG C NH2 1 
ATOM   7035  N N   . HIS C 1 20  ? -16.730 -48.783 4.091   1.00 47.07  ? 20  HIS C N   1 
ATOM   7036  C CA  . HIS C 1 20  ? -15.469 -49.145 4.711   1.00 44.13  ? 20  HIS C CA  1 
ATOM   7037  C C   . HIS C 1 20  ? -14.337 -48.938 3.711   1.00 39.58  ? 20  HIS C C   1 
ATOM   7038  O O   . HIS C 1 20  ? -14.538 -49.034 2.510   1.00 37.47  ? 20  HIS C O   1 
ATOM   7039  C CB  . HIS C 1 20  ? -15.504 -50.603 5.189   1.00 44.48  ? 20  HIS C CB  1 
ATOM   7040  C CG  . HIS C 1 20  ? -16.464 -50.857 6.298   1.00 48.39  ? 20  HIS C CG  1 
ATOM   7041  N ND1 . HIS C 1 20  ? -17.713 -51.400 6.076   1.00 48.19  ? 20  HIS C ND1 1 
ATOM   7042  C CD2 . HIS C 1 20  ? -16.364 -50.679 7.651   1.00 50.14  ? 20  HIS C CD2 1 
ATOM   7043  C CE1 . HIS C 1 20  ? -18.343 -51.542 7.247   1.00 53.56  ? 20  HIS C CE1 1 
ATOM   7044  N NE2 . HIS C 1 20  ? -17.532 -51.118 8.215   1.00 49.15  ? 20  HIS C NE2 1 
ATOM   7045  N N   . GLY C 1 21  ? -13.137 -48.685 4.235   1.00 39.03  ? 21  GLY C N   1 
ATOM   7046  C CA  . GLY C 1 21  ? -11.952 -48.564 3.419   1.00 40.23  ? 21  GLY C CA  1 
ATOM   7047  C C   . GLY C 1 21  ? -11.442 -49.940 3.010   1.00 40.11  ? 21  GLY C C   1 
ATOM   7048  O O   . GLY C 1 21  ? -11.729 -50.925 3.669   1.00 39.98  ? 21  GLY C O   1 
ATOM   7049  N N   . ARG C 1 22  ? -10.629 -49.969 1.951   1.00 46.56  ? 22  ARG C N   1 
ATOM   7050  C CA  . ARG C 1 22  ? -10.191 -51.215 1.320   1.00 45.46  ? 22  ARG C CA  1 
ATOM   7051  C C   . ARG C 1 22  ? -8.718  -51.494 1.645   1.00 45.51  ? 22  ARG C C   1 
ATOM   7052  O O   . ARG C 1 22  ? -8.110  -52.356 1.026   1.00 42.16  ? 22  ARG C O   1 
ATOM   7053  C CB  . ARG C 1 22  ? -10.356 -51.124 -0.193  1.00 45.32  ? 22  ARG C CB  1 
ATOM   7054  C CG  . ARG C 1 22  ? -11.700 -50.563 -0.632  1.00 52.90  ? 22  ARG C CG  1 
ATOM   7055  C CD  . ARG C 1 22  ? -12.282 -51.283 -1.811  1.00 62.21  ? 22  ARG C CD  1 
ATOM   7056  N NE  . ARG C 1 22  ? -13.750 -51.170 -1.827  1.00 70.41  ? 22  ARG C NE  1 
ATOM   7057  C CZ  . ARG C 1 22  ? -14.437 -50.222 -2.469  1.00 79.66  ? 22  ARG C CZ  1 
ATOM   7058  N NH1 . ARG C 1 22  ? -13.797 -49.286 -3.149  1.00 85.53  ? 22  ARG C NH1 1 
ATOM   7059  N NH2 . ARG C 1 22  ? -15.765 -50.222 -2.438  1.00 80.30  ? 22  ARG C NH2 1 
ATOM   7060  N N   . ALA C 1 23  ? -8.159  -50.785 2.629   1.00 41.65  ? 23  ALA C N   1 
ATOM   7061  C CA  . ALA C 1 23  ? -6.715  -50.933 2.941   1.00 40.78  ? 23  ALA C CA  1 
ATOM   7062  C C   . ALA C 1 23  ? -6.400  -52.301 3.556   1.00 40.04  ? 23  ALA C C   1 
ATOM   7063  O O   . ALA C 1 23  ? -5.233  -52.727 3.473   1.00 36.65  ? 23  ALA C O   1 
ATOM   7064  C CB  . ALA C 1 23  ? -6.274  -49.814 3.851   1.00 42.08  ? 23  ALA C CB  1 
ATOM   7065  N N   . GLY C 1 24  ? -7.391  -52.961 4.161   1.00 39.21  ? 24  GLY C N   1 
ATOM   7066  C CA  . GLY C 1 24  ? -7.155  -54.263 4.815   1.00 37.61  ? 24  GLY C CA  1 
ATOM   7067  C C   . GLY C 1 24  ? -6.536  -54.096 6.188   1.00 42.32  ? 24  GLY C C   1 
ATOM   7068  O O   . GLY C 1 24  ? -6.098  -55.110 6.761   1.00 39.85  ? 24  GLY C O   1 
ATOM   7069  N N   . ARG C 1 25  ? -6.480  -52.862 6.690   1.00 47.14  ? 25  ARG C N   1 
ATOM   7070  C CA  . ARG C 1 25  ? -5.917  -52.578 8.037   1.00 46.06  ? 25  ARG C CA  1 
ATOM   7071  C C   . ARG C 1 25  ? -7.012  -51.911 8.883   1.00 42.37  ? 25  ARG C C   1 
ATOM   7072  O O   . ARG C 1 25  ? -7.772  -51.096 8.329   1.00 42.37  ? 25  ARG C O   1 
ATOM   7073  C CB  . ARG C 1 25  ? -4.646  -51.725 7.966   1.00 50.64  ? 25  ARG C CB  1 
ATOM   7074  N N   . ARG C 1 26  ? -7.113  -52.282 10.157  1.00 43.84  ? 26  ARG C N   1 
ATOM   7075  C CA  . ARG C 1 26  ? -8.201  -51.753 11.018  1.00 49.49  ? 26  ARG C CA  1 
ATOM   7076  C C   . ARG C 1 26  ? -7.612  -50.780 12.047  1.00 49.33  ? 26  ARG C C   1 
ATOM   7077  O O   . ARG C 1 26  ? -6.597  -51.125 12.681  1.00 61.18  ? 26  ARG C O   1 
ATOM   7078  C CB  . ARG C 1 26  ? -8.952  -52.890 11.716  1.00 63.99  ? 26  ARG C CB  1 
ATOM   7079  N N   . LEU C 1 27  ? -8.228  -49.607 12.188  1.00 48.16  ? 27  LEU C N   1 
ATOM   7080  C CA  . LEU C 1 27  ? -7.739  -48.586 13.146  1.00 47.02  ? 27  LEU C CA  1 
ATOM   7081  C C   . LEU C 1 27  ? -8.706  -48.556 14.332  1.00 44.28  ? 27  LEU C C   1 
ATOM   7082  O O   . LEU C 1 27  ? -9.930  -48.498 14.106  1.00 44.47  ? 27  LEU C O   1 
ATOM   7083  C CB  . LEU C 1 27  ? -7.636  -47.210 12.492  1.00 45.65  ? 27  LEU C CB  1 
ATOM   7084  C CG  . LEU C 1 27  ? -7.471  -46.023 13.445  1.00 43.78  ? 27  LEU C CG  1 
ATOM   7085  C CD1 . LEU C 1 27  ? -6.051  -45.496 13.402  1.00 43.79  ? 27  LEU C CD1 1 
ATOM   7086  C CD2 . LEU C 1 27  ? -8.461  -44.920 13.127  1.00 43.28  ? 27  LEU C CD2 1 
ATOM   7087  N N   . LYS C 1 28  ? -8.164  -48.610 15.546  1.00 50.15  ? 28  LYS C N   1 
ATOM   7088  C CA  . LYS C 1 28  ? -9.026  -48.647 16.747  1.00 53.29  ? 28  LYS C CA  1 
ATOM   7089  C C   . LYS C 1 28  ? -9.007  -47.263 17.392  1.00 52.10  ? 28  LYS C C   1 
ATOM   7090  O O   . LYS C 1 28  ? -7.904  -46.738 17.647  1.00 47.09  ? 28  LYS C O   1 
ATOM   7091  C CB  . LYS C 1 28  ? -8.481  -49.672 17.744  1.00 58.34  ? 28  LYS C CB  1 
ATOM   7092  C CG  . LYS C 1 28  ? -8.195  -51.043 17.156  1.00 72.67  ? 28  LYS C CG  1 
ATOM   7093  C CD  . LYS C 1 28  ? -9.461  -51.837 16.858  1.00 79.16  ? 28  LYS C CD  1 
ATOM   7094  C CE  . LYS C 1 28  ? -9.552  -53.086 17.674  1.00 86.06  ? 28  LYS C CE  1 
ATOM   7095  N NZ  . LYS C 1 28  ? -9.329  -52.831 19.099  1.00 90.71  ? 28  LYS C NZ  1 
ATOM   7096  N N   . VAL C 1 29  ? -10.189 -46.695 17.618  1.00 43.58  ? 29  VAL C N   1 
ATOM   7097  C CA  . VAL C 1 29  ? -10.261 -45.376 18.308  1.00 44.93  ? 29  VAL C CA  1 
ATOM   7098  C C   . VAL C 1 29  ? -10.490 -45.657 19.795  1.00 46.15  ? 29  VAL C C   1 
ATOM   7099  O O   . VAL C 1 29  ? -11.430 -46.409 20.117  1.00 44.41  ? 29  VAL C O   1 
ATOM   7100  C CB  . VAL C 1 29  ? -11.315 -44.445 17.687  1.00 44.76  ? 29  VAL C CB  1 
ATOM   7101  C CG1 . VAL C 1 29  ? -11.234 -43.044 18.276  1.00 46.85  ? 29  VAL C CG1 1 
ATOM   7102  C CG2 . VAL C 1 29  ? -11.164 -44.398 16.172  1.00 42.55  ? 29  VAL C CG2 1 
ATOM   7103  N N   . SER C 1 30  ? -9.664  -45.069 20.655  1.00 51.71  ? 30  SER C N   1 
ATOM   7104  C CA  . SER C 1 30  ? -9.699  -45.384 22.071  1.00 56.57  ? 30  SER C CA  1 
ATOM   7105  C C   . SER C 1 30  ? -9.848  -44.103 22.891  1.00 53.24  ? 30  SER C C   1 
ATOM   7106  O O   . SER C 1 30  ? -9.328  -43.056 22.515  1.00 50.81  ? 30  SER C O   1 
ATOM   7107  C CB  . SER C 1 30  ? -8.448  -46.150 22.496  1.00 59.76  ? 30  SER C CB  1 
ATOM   7108  O OG  . SER C 1 30  ? -8.032  -47.071 21.494  1.00 66.50  ? 30  SER C OG  1 
ATOM   7109  N N   . ASN C 1 31  ? -10.471 -44.239 24.069  1.00 47.55  ? 31  ASN C N   1 
ATOM   7110  C CA  . ASN C 1 31  ? -10.564 -43.165 25.030  1.00 39.93  ? 31  ASN C CA  1 
ATOM   7111  C C   . ASN C 1 31  ? -9.218  -43.002 25.732  1.00 42.48  ? 31  ASN C C   1 
ATOM   7112  O O   . ASN C 1 31  ? -8.698  -43.949 26.293  1.00 51.51  ? 31  ASN C O   1 
ATOM   7113  C CB  . ASN C 1 31  ? -11.688 -43.430 26.008  1.00 38.55  ? 31  ASN C CB  1 
ATOM   7114  C CG  . ASN C 1 31  ? -11.972 -42.242 26.887  1.00 32.94  ? 31  ASN C CG  1 
ATOM   7115  O OD1 . ASN C 1 31  ? -11.044 -41.535 27.289  1.00 32.46  ? 31  ASN C OD1 1 
ATOM   7116  N ND2 . ASN C 1 31  ? -13.240 -42.020 27.211  1.00 32.13  ? 31  ASN C ND2 1 
ATOM   7117  N N   . PRO C 1 32  ? -8.579  -41.813 25.674  1.00 40.88  ? 32  PRO C N   1 
ATOM   7118  C CA  . PRO C 1 32  ? -7.274  -41.621 26.310  1.00 43.29  ? 32  PRO C CA  1 
ATOM   7119  C C   . PRO C 1 32  ? -7.275  -41.785 27.827  1.00 48.74  ? 32  PRO C C   1 
ATOM   7120  O O   . PRO C 1 32  ? -6.225  -42.026 28.417  1.00 50.40  ? 32  PRO C O   1 
ATOM   7121  C CB  . PRO C 1 32  ? -6.885  -40.186 25.893  1.00 42.16  ? 32  PRO C CB  1 
ATOM   7122  C CG  . PRO C 1 32  ? -7.674  -39.946 24.642  1.00 44.57  ? 32  PRO C CG  1 
ATOM   7123  C CD  . PRO C 1 32  ? -8.986  -40.666 24.867  1.00 41.66  ? 32  PRO C CD  1 
ATOM   7124  N N   . PHE C 1 33  ? -8.450  -41.588 28.455  1.00 45.60  ? 33  PHE C N   1 
ATOM   7125  C CA  . PHE C 1 33  ? -8.556  -41.631 29.898  1.00 48.24  ? 33  PHE C CA  1 
ATOM   7126  C C   . PHE C 1 33  ? -8.458  -43.093 30.381  1.00 53.21  ? 33  PHE C C   1 
ATOM   7127  O O   . PHE C 1 33  ? -7.519  -43.447 31.089  1.00 48.30  ? 33  PHE C O   1 
ATOM   7128  C CB  . PHE C 1 33  ? -9.848  -40.958 30.365  1.00 48.43  ? 33  PHE C CB  1 
ATOM   7129  C CG  . PHE C 1 33  ? -9.958  -40.872 31.877  1.00 54.78  ? 33  PHE C CG  1 
ATOM   7130  C CD1 . PHE C 1 33  ? -9.074  -40.069 32.604  1.00 63.79  ? 33  PHE C CD1 1 
ATOM   7131  C CD2 . PHE C 1 33  ? -10.920 -41.605 32.580  1.00 53.94  ? 33  PHE C CD2 1 
ATOM   7132  C CE1 . PHE C 1 33  ? -9.151  -39.997 33.989  1.00 66.39  ? 33  PHE C CE1 1 
ATOM   7133  C CE2 . PHE C 1 33  ? -11.010 -41.508 33.968  1.00 54.59  ? 33  PHE C CE2 1 
ATOM   7134  C CZ  . PHE C 1 33  ? -10.129 -40.710 34.669  1.00 56.28  ? 33  PHE C CZ  1 
ATOM   7135  N N   . ASP C 1 34  ? -9.458  -43.918 30.017  1.00 58.10  ? 34  ASP C N   1 
ATOM   7136  C CA  . ASP C 1 34  ? -9.598  -45.260 30.573  1.00 62.40  ? 34  ASP C CA  1 
ATOM   7137  C C   . ASP C 1 34  ? -9.003  -46.304 29.608  1.00 61.87  ? 34  ASP C C   1 
ATOM   7138  O O   . ASP C 1 34  ? -8.874  -47.479 29.962  1.00 59.83  ? 34  ASP C O   1 
ATOM   7139  C CB  . ASP C 1 34  ? -11.054 -45.557 30.905  1.00 60.04  ? 34  ASP C CB  1 
ATOM   7140  C CG  . ASP C 1 34  ? -12.013 -45.469 29.731  1.00 66.80  ? 34  ASP C CG  1 
ATOM   7141  O OD1 . ASP C 1 34  ? -13.252 -45.488 29.979  1.00 60.61  ? 34  ASP C OD1 1 
ATOM   7142  O OD2 . ASP C 1 34  ? -11.513 -45.386 28.565  1.00 64.94  ? 34  ASP C OD2 1 
ATOM   7143  N N   . GLY C 1 35  ? -8.702  -45.882 28.371  1.00 56.34  ? 35  GLY C N   1 
ATOM   7144  C CA  . GLY C 1 35  ? -8.145  -46.782 27.364  1.00 49.90  ? 35  GLY C CA  1 
ATOM   7145  C C   . GLY C 1 35  ? -9.227  -47.594 26.632  1.00 49.83  ? 35  GLY C C   1 
ATOM   7146  O O   . GLY C 1 35  ? -8.906  -48.433 25.824  1.00 52.66  ? 35  GLY C O   1 
ATOM   7147  N N   . SER C 1 36  ? -10.506 -47.308 26.904  1.00 53.61  ? 36  SER C N   1 
ATOM   7148  C CA  . SER C 1 36  ? -11.608 -48.123 26.396  1.00 53.41  ? 36  SER C CA  1 
ATOM   7149  C C   . SER C 1 36  ? -11.828 -47.893 24.875  1.00 55.48  ? 36  SER C C   1 
ATOM   7150  O O   . SER C 1 36  ? -11.576 -46.811 24.350  1.00 51.09  ? 36  SER C O   1 
ATOM   7151  C CB  . SER C 1 36  ? -12.888 -47.850 27.195  1.00 53.92  ? 36  SER C CB  1 
ATOM   7152  O OG  . SER C 1 36  ? -13.340 -46.517 27.006  1.00 59.58  ? 36  SER C OG  1 
ATOM   7153  N N   . LEU C 1 37  ? -12.383 -48.918 24.207  1.00 55.21  ? 37  LEU C N   1 
ATOM   7154  C CA  . LEU C 1 37  ? -12.587 -48.918 22.759  1.00 60.04  ? 37  LEU C CA  1 
ATOM   7155  C C   . LEU C 1 37  ? -13.852 -48.122 22.402  1.00 56.55  ? 37  LEU C C   1 
ATOM   7156  O O   . LEU C 1 37  ? -14.950 -48.496 22.795  1.00 57.31  ? 37  LEU C O   1 
ATOM   7157  C CB  . LEU C 1 37  ? -12.689 -50.392 22.312  1.00 62.42  ? 37  LEU C CB  1 
ATOM   7158  C CG  . LEU C 1 37  ? -12.556 -50.704 20.800  1.00 60.99  ? 37  LEU C CG  1 
ATOM   7159  C CD1 . LEU C 1 37  ? -13.852 -50.467 20.042  1.00 65.10  ? 37  LEU C CD1 1 
ATOM   7160  C CD2 . LEU C 1 37  ? -11.430 -49.922 20.163  1.00 65.68  ? 37  LEU C CD2 1 
ATOM   7161  N N   . LEU C 1 38  ? -13.688 -47.050 21.608  1.00 52.59  ? 38  LEU C N   1 
ATOM   7162  C CA  . LEU C 1 38  ? -14.823 -46.238 21.164  1.00 50.16  ? 38  LEU C CA  1 
ATOM   7163  C C   . LEU C 1 38  ? -15.427 -46.852 19.905  1.00 50.84  ? 38  LEU C C   1 
ATOM   7164  O O   . LEU C 1 38  ? -16.627 -47.104 19.858  1.00 58.73  ? 38  LEU C O   1 
ATOM   7165  C CB  . LEU C 1 38  ? -14.413 -44.789 20.925  1.00 47.25  ? 38  LEU C CB  1 
ATOM   7166  C CG  . LEU C 1 38  ? -13.834 -44.053 22.133  1.00 50.50  ? 38  LEU C CG  1 
ATOM   7167  C CD1 . LEU C 1 38  ? -13.543 -42.604 21.799  1.00 49.81  ? 38  LEU C CD1 1 
ATOM   7168  C CD2 . LEU C 1 38  ? -14.769 -44.147 23.323  1.00 49.54  ? 38  LEU C CD2 1 
ATOM   7169  N N   . LEU C 1 39  ? -14.595 -47.049 18.874  1.00 44.82  ? 39  LEU C N   1 
ATOM   7170  C CA  . LEU C 1 39  ? -15.046 -47.666 17.642  1.00 44.85  ? 39  LEU C CA  1 
ATOM   7171  C C   . LEU C 1 39  ? -13.847 -48.209 16.864  1.00 43.35  ? 39  LEU C C   1 
ATOM   7172  O O   . LEU C 1 39  ? -12.693 -48.015 17.252  1.00 51.39  ? 39  LEU C O   1 
ATOM   7173  C CB  . LEU C 1 39  ? -15.882 -46.683 16.797  1.00 48.93  ? 39  LEU C CB  1 
ATOM   7174  C CG  . LEU C 1 39  ? -15.120 -45.646 15.962  1.00 53.15  ? 39  LEU C CG  1 
ATOM   7175  C CD1 . LEU C 1 39  ? -16.019 -45.048 14.903  1.00 60.33  ? 39  LEU C CD1 1 
ATOM   7176  C CD2 . LEU C 1 39  ? -14.572 -44.552 16.819  1.00 58.78  ? 39  LEU C CD2 1 
ATOM   7177  N N   . GLU C 1 40  ? -14.155 -48.914 15.771  1.00 46.39  ? 40  GLU C N   1 
ATOM   7178  C CA  . GLU C 1 40  ? -13.155 -49.481 14.890  1.00 53.77  ? 40  GLU C CA  1 
ATOM   7179  C C   . GLU C 1 40  ? -13.394 -48.957 13.482  1.00 47.61  ? 40  GLU C C   1 
ATOM   7180  O O   . GLU C 1 40  ? -14.541 -48.820 13.073  1.00 46.70  ? 40  GLU C O   1 
ATOM   7181  C CB  . GLU C 1 40  ? -13.288 -51.001 14.888  1.00 66.55  ? 40  GLU C CB  1 
ATOM   7182  C CG  . GLU C 1 40  ? -13.092 -51.640 16.264  1.00 76.25  ? 40  GLU C CG  1 
ATOM   7183  C CD  . GLU C 1 40  ? -13.256 -53.156 16.289  1.00 82.47  ? 40  GLU C CD  1 
ATOM   7184  O OE1 . GLU C 1 40  ? -13.708 -53.735 15.283  1.00 91.33  ? 40  GLU C OE1 1 
ATOM   7185  O OE2 . GLU C 1 40  ? -12.855 -53.762 17.297  1.00 94.26  ? 40  GLU C OE2 1 
ATOM   7186  N N   . ILE C 1 41  ? -12.310 -48.689 12.739  1.00 41.38  ? 41  ILE C N   1 
ATOM   7187  C CA  . ILE C 1 41  ? -12.430 -48.124 11.404  1.00 43.60  ? 41  ILE C CA  1 
ATOM   7188  C C   . ILE C 1 41  ? -11.623 -48.960 10.421  1.00 43.75  ? 41  ILE C C   1 
ATOM   7189  O O   . ILE C 1 41  ? -10.425 -49.183 10.629  1.00 41.23  ? 41  ILE C O   1 
ATOM   7190  C CB  . ILE C 1 41  ? -11.978 -46.648 11.374  1.00 43.72  ? 41  ILE C CB  1 
ATOM   7191  C CG1 . ILE C 1 41  ? -12.832 -45.775 12.346  1.00 44.59  ? 41  ILE C CG1 1 
ATOM   7192  C CG2 . ILE C 1 41  ? -11.995 -46.103 9.932   1.00 39.89  ? 41  ILE C CG2 1 
ATOM   7193  C CD1 . ILE C 1 41  ? -12.518 -44.297 12.307  1.00 42.37  ? 41  ILE C CD1 1 
ATOM   7194  N N   . GLU C 1 42  ? -12.270 -49.330 9.300   1.00 43.16  ? 42  GLU C N   1 
ATOM   7195  C CA  . GLU C 1 42  ? -11.574 -49.916 8.157   1.00 43.41  ? 42  GLU C CA  1 
ATOM   7196  C C   . GLU C 1 42  ? -10.834 -48.812 7.399   1.00 40.50  ? 42  GLU C C   1 
ATOM   7197  O O   . GLU C 1 42  ? -11.457 -48.013 6.726   1.00 37.54  ? 42  GLU C O   1 
ATOM   7198  C CB  . GLU C 1 42  ? -12.536 -50.604 7.179   1.00 41.71  ? 42  GLU C CB  1 
ATOM   7199  C CG  . GLU C 1 42  ? -13.026 -51.971 7.641   1.00 41.40  ? 42  GLU C CG  1 
ATOM   7200  C CD  . GLU C 1 42  ? -11.939 -52.987 7.880   1.00 44.81  ? 42  GLU C CD  1 
ATOM   7201  O OE1 . GLU C 1 42  ? -10.774 -52.879 7.320   1.00 53.02  ? 42  GLU C OE1 1 
ATOM   7202  O OE2 . GLU C 1 42  ? -12.243 -53.880 8.673   1.00 42.38  ? 42  GLU C OE2 1 
ATOM   7203  N N   . GLN C 1 43  ? -9.503  -48.839 7.459   1.00 39.43  ? 43  GLN C N   1 
ATOM   7204  C CA  . GLN C 1 43  ? -8.682  -47.772 6.927   1.00 42.56  ? 43  GLN C CA  1 
ATOM   7205  C C   . GLN C 1 43  ? -8.781  -47.712 5.410   1.00 38.82  ? 43  GLN C C   1 
ATOM   7206  O O   . GLN C 1 43  ? -9.105  -48.680 4.760   1.00 41.89  ? 43  GLN C O   1 
ATOM   7207  C CB  . GLN C 1 43  ? -7.232  -47.957 7.353   1.00 52.09  ? 43  GLN C CB  1 
ATOM   7208  C CG  . GLN C 1 43  ? -7.040  -47.971 8.870   1.00 59.02  ? 43  GLN C CG  1 
ATOM   7209  C CD  . GLN C 1 43  ? -5.683  -47.482 9.299   1.00 54.65  ? 43  GLN C CD  1 
ATOM   7210  O OE1 . GLN C 1 43  ? -4.766  -48.260 9.528   1.00 53.45  ? 43  GLN C OE1 1 
ATOM   7211  N NE2 . GLN C 1 43  ? -5.552  -46.178 9.418   1.00 63.00  ? 43  GLN C NE2 1 
ATOM   7212  N N   . ALA C 1 44  ? -8.436  -46.552 4.874   1.00 41.27  ? 44  ALA C N   1 
ATOM   7213  C CA  . ALA C 1 44  ? -8.521  -46.276 3.454   1.00 41.46  ? 44  ALA C CA  1 
ATOM   7214  C C   . ALA C 1 44  ? -7.175  -46.534 2.795   1.00 35.69  ? 44  ALA C C   1 
ATOM   7215  O O   . ALA C 1 44  ? -6.136  -46.264 3.374   1.00 33.44  ? 44  ALA C O   1 
ATOM   7216  C CB  . ALA C 1 44  ? -8.958  -44.839 3.242   1.00 43.42  ? 44  ALA C CB  1 
ATOM   7217  N N   . ASP C 1 45  ? -7.216  -47.040 1.566   1.00 39.39  ? 45  ASP C N   1 
ATOM   7218  C CA  . ASP C 1 45  ? -6.005  -47.234 0.779   1.00 44.28  ? 45  ASP C CA  1 
ATOM   7219  C C   . ASP C 1 45  ? -5.868  -46.070 -0.195  1.00 43.96  ? 45  ASP C C   1 
ATOM   7220  O O   . ASP C 1 45  ? -6.692  -45.171 -0.198  1.00 46.34  ? 45  ASP C O   1 
ATOM   7221  C CB  . ASP C 1 45  ? -5.989  -48.602 0.097   1.00 40.26  ? 45  ASP C CB  1 
ATOM   7222  C CG  . ASP C 1 45  ? -7.074  -48.862 -0.932  1.00 46.90  ? 45  ASP C CG  1 
ATOM   7223  O OD1 . ASP C 1 45  ? -7.742  -47.853 -1.411  1.00 47.69  ? 45  ASP C OD1 1 
ATOM   7224  O OD2 . ASP C 1 45  ? -7.282  -50.051 -1.240  1.00 54.61  ? 45  ASP C OD2 1 
ATOM   7225  N N   . ARG C 1 46  ? -4.853  -46.148 -1.058  1.00 43.87  ? 46  ARG C N   1 
ATOM   7226  C CA  . ARG C 1 46  ? -4.523  -45.086 -1.982  1.00 46.37  ? 46  ARG C CA  1 
ATOM   7227  C C   . ARG C 1 46  ? -5.603  -44.956 -3.043  1.00 46.18  ? 46  ARG C C   1 
ATOM   7228  O O   . ARG C 1 46  ? -5.833  -43.873 -3.541  1.00 47.40  ? 46  ARG C O   1 
ATOM   7229  C CB  . ARG C 1 46  ? -3.187  -45.399 -2.642  1.00 55.55  ? 46  ARG C CB  1 
ATOM   7230  C CG  . ARG C 1 46  ? -2.690  -44.331 -3.591  1.00 63.17  ? 46  ARG C CG  1 
ATOM   7231  C CD  . ARG C 1 46  ? -1.802  -43.353 -2.904  1.00 68.71  ? 46  ARG C CD  1 
ATOM   7232  N NE  . ARG C 1 46  ? -0.716  -42.957 -3.805  1.00 76.51  ? 46  ARG C NE  1 
ATOM   7233  C CZ  . ARG C 1 46  ? 0.536   -43.372 -3.689  1.00 76.91  ? 46  ARG C CZ  1 
ATOM   7234  N NH1 . ARG C 1 46  ? 0.855   -44.259 -2.751  1.00 73.39  ? 46  ARG C NH1 1 
ATOM   7235  N NH2 . ARG C 1 46  ? 1.469   -42.894 -4.503  1.00 80.08  ? 46  ARG C NH2 1 
ATOM   7236  N N   . ASP C 1 47  ? -6.241  -46.070 -3.407  1.00 46.02  ? 47  ASP C N   1 
ATOM   7237  C CA  . ASP C 1 47  ? -7.294  -46.030 -4.413  1.00 46.56  ? 47  ASP C CA  1 
ATOM   7238  C C   . ASP C 1 47  ? -8.490  -45.271 -3.873  1.00 43.32  ? 47  ASP C C   1 
ATOM   7239  O O   . ASP C 1 47  ? -9.177  -44.583 -4.636  1.00 46.71  ? 47  ASP C O   1 
ATOM   7240  C CB  . ASP C 1 47  ? -7.734  -47.411 -4.860  1.00 49.61  ? 47  ASP C CB  1 
ATOM   7241  C CG  . ASP C 1 47  ? -6.866  -48.049 -5.912  1.00 54.07  ? 47  ASP C CG  1 
ATOM   7242  O OD1 . ASP C 1 47  ? -6.445  -49.189 -5.686  1.00 51.43  ? 47  ASP C OD1 1 
ATOM   7243  O OD2 . ASP C 1 47  ? -6.611  -47.384 -6.955  1.00 69.46  ? 47  ASP C OD2 1 
ATOM   7244  N N   . ASP C 1 48  ? -8.771  -45.437 -2.568  1.00 38.35  ? 48  ASP C N   1 
ATOM   7245  C CA  . ASP C 1 48  ? -9.853  -44.700 -1.934  1.00 37.09  ? 48  ASP C CA  1 
ATOM   7246  C C   . ASP C 1 48  ? -9.560  -43.187 -2.028  1.00 39.71  ? 48  ASP C C   1 
ATOM   7247  O O   . ASP C 1 48  ? -10.458 -42.396 -2.324  1.00 39.97  ? 48  ASP C O   1 
ATOM   7248  C CB  . ASP C 1 48  ? -10.101 -45.166 -0.509  1.00 37.49  ? 48  ASP C CB  1 
ATOM   7249  C CG  . ASP C 1 48  ? -10.629 -46.597 -0.349  1.00 44.65  ? 48  ASP C CG  1 
ATOM   7250  O OD1 . ASP C 1 48  ? -11.471 -47.002 -1.152  1.00 38.97  ? 48  ASP C OD1 1 
ATOM   7251  O OD2 . ASP C 1 48  ? -10.222 -47.274 0.629   1.00 48.19  ? 48  ASP C OD2 1 
ATOM   7252  N N   . LEU C 1 49  ? -8.284  -42.811 -1.835  1.00 36.97  ? 49  LEU C N   1 
ATOM   7253  C CA  . LEU C 1 49  ? -7.879  -41.418 -1.832  1.00 40.14  ? 49  LEU C CA  1 
ATOM   7254  C C   . LEU C 1 49  ? -8.110  -40.822 -3.212  1.00 42.66  ? 49  LEU C C   1 
ATOM   7255  O O   . LEU C 1 49  ? -8.650  -39.712 -3.334  1.00 45.22  ? 49  LEU C O   1 
ATOM   7256  C CB  . LEU C 1 49  ? -6.418  -41.281 -1.417  1.00 40.94  ? 49  LEU C CB  1 
ATOM   7257  C CG  . LEU C 1 49  ? -5.826  -39.883 -1.556  1.00 45.26  ? 49  LEU C CG  1 
ATOM   7258  C CD1 . LEU C 1 49  ? -6.482  -38.928 -0.575  1.00 47.07  ? 49  LEU C CD1 1 
ATOM   7259  C CD2 . LEU C 1 49  ? -4.335  -39.892 -1.357  1.00 52.22  ? 49  LEU C CD2 1 
ATOM   7260  N N   . ASP C 1 50  ? -7.669  -41.550 -4.243  1.00 43.58  ? 50  ASP C N   1 
ATOM   7261  C CA  . ASP C 1 50  ? -7.782  -41.090 -5.626  1.00 47.11  ? 50  ASP C CA  1 
ATOM   7262  C C   . ASP C 1 50  ? -9.254  -40.898 -5.990  1.00 43.95  ? 50  ASP C C   1 
ATOM   7263  O O   . ASP C 1 50  ? -9.605  -39.917 -6.629  1.00 42.35  ? 50  ASP C O   1 
ATOM   7264  C CB  . ASP C 1 50  ? -7.052  -42.026 -6.588  1.00 49.45  ? 50  ASP C CB  1 
ATOM   7265  C CG  . ASP C 1 50  ? -5.525  -41.894 -6.610  1.00 49.85  ? 50  ASP C CG  1 
ATOM   7266  O OD1 . ASP C 1 50  ? -4.990  -41.029 -5.871  1.00 55.49  ? 50  ASP C OD1 1 
ATOM   7267  O OD2 . ASP C 1 50  ? -4.880  -42.672 -7.331  1.00 50.23  ? 50  ASP C OD2 1 
ATOM   7268  N N   . ALA C 1 51  ? -10.109 -41.832 -5.552  1.00 43.78  ? 51  ALA C N   1 
ATOM   7269  C CA  . ALA C 1 51  ? -11.528 -41.783 -5.887  1.00 43.95  ? 51  ALA C CA  1 
ATOM   7270  C C   . ALA C 1 51  ? -12.190 -40.562 -5.228  1.00 43.40  ? 51  ALA C C   1 
ATOM   7271  O O   . ALA C 1 51  ? -12.989 -39.877 -5.862  1.00 43.67  ? 51  ALA C O   1 
ATOM   7272  C CB  . ALA C 1 51  ? -12.210 -43.077 -5.484  1.00 38.91  ? 51  ALA C CB  1 
ATOM   7273  N N   . ALA C 1 52  ? -11.852 -40.308 -3.953  1.00 41.11  ? 52  ALA C N   1 
ATOM   7274  C CA  . ALA C 1 52  ? -12.444 -39.205 -3.196  1.00 40.18  ? 52  ALA C CA  1 
ATOM   7275  C C   . ALA C 1 52  ? -12.116 -37.846 -3.856  1.00 42.33  ? 52  ALA C C   1 
ATOM   7276  O O   . ALA C 1 52  ? -13.008 -36.993 -4.012  1.00 34.61  ? 52  ALA C O   1 
ATOM   7277  C CB  . ALA C 1 52  ? -11.977 -39.257 -1.772  1.00 39.77  ? 52  ALA C CB  1 
ATOM   7278  N N   . TYR C 1 53  ? -10.845 -37.681 -4.287  1.00 41.39  ? 53  TYR C N   1 
ATOM   7279  C CA  . TYR C 1 53  ? -10.398 -36.464 -4.946  1.00 40.57  ? 53  TYR C CA  1 
ATOM   7280  C C   . TYR C 1 53  ? -11.100 -36.319 -6.293  1.00 43.14  ? 53  TYR C C   1 
ATOM   7281  O O   . TYR C 1 53  ? -11.527 -35.236 -6.650  1.00 41.69  ? 53  TYR C O   1 
ATOM   7282  C CB  . TYR C 1 53  ? -8.882  -36.455 -5.134  1.00 38.61  ? 53  TYR C CB  1 
ATOM   7283  C CG  . TYR C 1 53  ? -8.086  -35.783 -4.018  1.00 39.18  ? 53  TYR C CG  1 
ATOM   7284  C CD1 . TYR C 1 53  ? -8.530  -34.619 -3.421  1.00 36.45  ? 53  TYR C CD1 1 
ATOM   7285  C CD2 . TYR C 1 53  ? -6.867  -36.313 -3.580  1.00 39.68  ? 53  TYR C CD2 1 
ATOM   7286  C CE1 . TYR C 1 53  ? -7.799  -33.997 -2.423  1.00 36.40  ? 53  TYR C CE1 1 
ATOM   7287  C CE2 . TYR C 1 53  ? -6.127  -35.701 -2.590  1.00 37.01  ? 53  TYR C CE2 1 
ATOM   7288  C CZ  . TYR C 1 53  ? -6.595  -34.534 -2.006  1.00 38.05  ? 53  TYR C CZ  1 
ATOM   7289  O OH  . TYR C 1 53  ? -5.870  -33.911 -1.025  1.00 32.98  ? 53  TYR C OH  1 
ATOM   7290  N N   . ALA C 1 54  ? -11.194 -37.413 -7.044  1.00 44.51  ? 54  ALA C N   1 
ATOM   7291  C CA  . ALA C 1 54  ? -11.743 -37.369 -8.401  1.00 43.68  ? 54  ALA C CA  1 
ATOM   7292  C C   . ALA C 1 54  ? -13.228 -36.995 -8.367  1.00 39.99  ? 54  ALA C C   1 
ATOM   7293  O O   . ALA C 1 54  ? -13.668 -36.153 -9.140  1.00 41.16  ? 54  ALA C O   1 
ATOM   7294  C CB  . ALA C 1 54  ? -11.530 -38.696 -9.089  1.00 46.14  ? 54  ALA C CB  1 
ATOM   7295  N N   . LYS C 1 55  ? -13.981 -37.617 -7.441  1.00 38.91  ? 55  LYS C N   1 
ATOM   7296  C CA  . LYS C 1 55  ? -15.391 -37.303 -7.247  1.00 39.95  ? 55  LYS C CA  1 
ATOM   7297  C C   . LYS C 1 55  ? -15.564 -35.826 -6.858  1.00 42.00  ? 55  LYS C C   1 
ATOM   7298  O O   . LYS C 1 55  ? -16.436 -35.141 -7.390  1.00 44.09  ? 55  LYS C O   1 
ATOM   7299  C CB  . LYS C 1 55  ? -16.004 -38.193 -6.182  1.00 42.00  ? 55  LYS C CB  1 
ATOM   7300  C CG  . LYS C 1 55  ? -17.363 -37.752 -5.700  1.00 48.81  ? 55  LYS C CG  1 
ATOM   7301  C CD  . LYS C 1 55  ? -18.463 -37.835 -6.750  1.00 55.71  ? 55  LYS C CD  1 
ATOM   7302  C CE  . LYS C 1 55  ? -18.729 -39.238 -7.255  1.00 57.31  ? 55  LYS C CE  1 
ATOM   7303  N NZ  . LYS C 1 55  ? -19.618 -39.210 -8.423  1.00 59.39  ? 55  LYS C NZ  1 
ATOM   7304  N N   . ALA C 1 56  ? -14.736 -35.345 -5.926  1.00 37.55  ? 56  ALA C N   1 
ATOM   7305  C CA  . ALA C 1 56  ? -14.833 -33.963 -5.483  1.00 40.78  ? 56  ALA C CA  1 
ATOM   7306  C C   . ALA C 1 56  ? -14.687 -33.018 -6.673  1.00 40.74  ? 56  ALA C C   1 
ATOM   7307  O O   . ALA C 1 56  ? -15.435 -32.058 -6.786  1.00 42.66  ? 56  ALA C O   1 
ATOM   7308  C CB  . ALA C 1 56  ? -13.815 -33.670 -4.425  1.00 42.12  ? 56  ALA C CB  1 
ATOM   7309  N N   . ALA C 1 57  ? -13.728 -33.310 -7.556  1.00 42.37  ? 57  ALA C N   1 
ATOM   7310  C CA  . ALA C 1 57  ? -13.492 -32.496 -8.745  1.00 41.17  ? 57  ALA C CA  1 
ATOM   7311  C C   . ALA C 1 57  ? -14.708 -32.537 -9.666  1.00 44.16  ? 57  ALA C C   1 
ATOM   7312  O O   . ALA C 1 57  ? -15.047 -31.535 -10.288 1.00 48.70  ? 57  ALA C O   1 
ATOM   7313  C CB  . ALA C 1 57  ? -12.253 -32.976 -9.472  1.00 37.54  ? 57  ALA C CB  1 
ATOM   7314  N N   . GLU C 1 58  ? -15.348 -33.705 -9.743  1.00 46.37  ? 58  GLU C N   1 
ATOM   7315  C CA  . GLU C 1 58  ? -16.431 -33.944 -10.696 1.00 51.14  ? 58  GLU C CA  1 
ATOM   7316  C C   . GLU C 1 58  ? -17.697 -33.142 -10.306 1.00 45.68  ? 58  GLU C C   1 
ATOM   7317  O O   . GLU C 1 58  ? -18.334 -32.557 -11.164 1.00 51.41  ? 58  GLU C O   1 
ATOM   7318  C CB  . GLU C 1 58  ? -16.666 -35.458 -10.831 1.00 51.97  ? 58  GLU C CB  1 
ATOM   7319  C CG  . GLU C 1 58  ? -18.130 -35.852 -10.981 1.00 64.18  ? 58  GLU C CG  1 
ATOM   7320  C CD  . GLU C 1 58  ? -18.370 -37.368 -10.966 1.00 74.99  ? 58  GLU C CD  1 
ATOM   7321  O OE1 . GLU C 1 58  ? -19.198 -37.849 -11.768 1.00 72.70  ? 58  GLU C OE1 1 
ATOM   7322  O OE2 . GLU C 1 58  ? -17.711 -38.067 -10.161 1.00 83.38  ? 58  GLU C OE2 1 
ATOM   7323  N N   . VAL C 1 59  ? -18.061 -33.138 -9.018  1.00 40.93  ? 59  VAL C N   1 
ATOM   7324  C CA  . VAL C 1 59  ? -19.353 -32.591 -8.591  1.00 41.01  ? 59  VAL C CA  1 
ATOM   7325  C C   . VAL C 1 59  ? -19.221 -31.112 -8.175  1.00 38.51  ? 59  VAL C C   1 
ATOM   7326  O O   . VAL C 1 59  ? -20.217 -30.443 -7.985  1.00 36.40  ? 59  VAL C O   1 
ATOM   7327  C CB  . VAL C 1 59  ? -19.947 -33.410 -7.453  1.00 41.07  ? 59  VAL C CB  1 
ATOM   7328  C CG1 . VAL C 1 59  ? -20.315 -34.820 -7.908  1.00 42.53  ? 59  VAL C CG1 1 
ATOM   7329  C CG2 . VAL C 1 59  ? -19.013 -33.440 -6.246  1.00 44.02  ? 59  VAL C CG2 1 
ATOM   7330  N N   . GLN C 1 60  ? -17.994 -30.617 -8.050  1.00 40.17  ? 60  GLN C N   1 
ATOM   7331  C CA  . GLN C 1 60  ? -17.747 -29.291 -7.474  1.00 40.45  ? 60  GLN C CA  1 
ATOM   7332  C C   . GLN C 1 60  ? -18.373 -28.190 -8.366  1.00 43.26  ? 60  GLN C C   1 
ATOM   7333  O O   . GLN C 1 60  ? -18.955 -27.228 -7.848  1.00 37.78  ? 60  GLN C O   1 
ATOM   7334  C CB  . GLN C 1 60  ? -16.237 -29.080 -7.228  1.00 35.43  ? 60  GLN C CB  1 
ATOM   7335  C CG  . GLN C 1 60  ? -15.873 -27.705 -6.674  1.00 37.96  ? 60  GLN C CG  1 
ATOM   7336  C CD  . GLN C 1 60  ? -15.605 -26.666 -7.753  1.00 38.80  ? 60  GLN C CD  1 
ATOM   7337  O OE1 . GLN C 1 60  ? -15.237 -26.992 -8.876  1.00 38.35  ? 60  GLN C OE1 1 
ATOM   7338  N NE2 . GLN C 1 60  ? -15.804 -25.400 -7.420  1.00 41.19  ? 60  GLN C NE2 1 
ATOM   7339  N N   . PRO C 1 61  ? -18.254 -28.257 -9.719  1.00 45.49  ? 61  PRO C N   1 
ATOM   7340  C CA  . PRO C 1 61  ? -18.793 -27.187 -10.581 1.00 46.49  ? 61  PRO C CA  1 
ATOM   7341  C C   . PRO C 1 61  ? -20.300 -26.954 -10.426 1.00 44.27  ? 61  PRO C C   1 
ATOM   7342  O O   . PRO C 1 61  ? -20.749 -25.816 -10.399 1.00 42.07  ? 61  PRO C O   1 
ATOM   7343  C CB  . PRO C 1 61  ? -18.414 -27.664 -11.992 1.00 43.65  ? 61  PRO C CB  1 
ATOM   7344  C CG  . PRO C 1 61  ? -17.169 -28.473 -11.771 1.00 41.77  ? 61  PRO C CG  1 
ATOM   7345  C CD  . PRO C 1 61  ? -17.471 -29.243 -10.479 1.00 47.14  ? 61  PRO C CD  1 
ATOM   7346  N N   . ALA C 1 62  ? -21.059 -28.038 -10.230 1.00 42.40  ? 62  ALA C N   1 
ATOM   7347  C CA  . ALA C 1 62  ? -22.498 -27.931 -10.026 1.00 42.90  ? 62  ALA C CA  1 
ATOM   7348  C C   . ALA C 1 62  ? -22.802 -27.212 -8.702  1.00 47.00  ? 62  ALA C C   1 
ATOM   7349  O O   . ALA C 1 62  ? -23.766 -26.459 -8.615  1.00 47.95  ? 62  ALA C O   1 
ATOM   7350  C CB  . ALA C 1 62  ? -23.126 -29.301 -10.063 1.00 42.55  ? 62  ALA C CB  1 
ATOM   7351  N N   . TRP C 1 63  ? -21.971 -27.466 -7.670  1.00 43.57  ? 63  TRP C N   1 
ATOM   7352  C CA  . TRP C 1 63  ? -22.130 -26.823 -6.373  1.00 35.99  ? 63  TRP C CA  1 
ATOM   7353  C C   . TRP C 1 63  ? -21.799 -25.334 -6.502  1.00 35.70  ? 63  TRP C C   1 
ATOM   7354  O O   . TRP C 1 63  ? -22.548 -24.479 -6.021  1.00 34.08  ? 63  TRP C O   1 
ATOM   7355  C CB  . TRP C 1 63  ? -21.255 -27.547 -5.336  1.00 35.72  ? 63  TRP C CB  1 
ATOM   7356  C CG  . TRP C 1 63  ? -21.115 -26.881 -3.993  1.00 33.33  ? 63  TRP C CG  1 
ATOM   7357  C CD1 . TRP C 1 63  ? -19.979 -26.339 -3.466  1.00 33.42  ? 63  TRP C CD1 1 
ATOM   7358  C CD2 . TRP C 1 63  ? -22.120 -26.756 -2.986  1.00 32.09  ? 63  TRP C CD2 1 
ATOM   7359  N NE1 . TRP C 1 63  ? -20.216 -25.884 -2.198  1.00 33.40  ? 63  TRP C NE1 1 
ATOM   7360  C CE2 . TRP C 1 63  ? -21.522 -26.113 -1.881  1.00 34.60  ? 63  TRP C CE2 1 
ATOM   7361  C CE3 . TRP C 1 63  ? -23.470 -27.087 -2.919  1.00 33.57  ? 63  TRP C CE3 1 
ATOM   7362  C CZ2 . TRP C 1 63  ? -22.240 -25.790 -0.721  1.00 36.29  ? 63  TRP C CZ2 1 
ATOM   7363  C CZ3 . TRP C 1 63  ? -24.181 -26.777 -1.773  1.00 35.33  ? 63  TRP C CZ3 1 
ATOM   7364  C CH2 . TRP C 1 63  ? -23.568 -26.150 -0.682  1.00 35.00  ? 63  TRP C CH2 1 
ATOM   7365  N N   . ALA C 1 64  ? -20.735 -25.029 -7.242  1.00 37.34  ? 64  ALA C N   1 
ATOM   7366  C CA  . ALA C 1 64  ? -20.349 -23.638 -7.485  1.00 44.04  ? 64  ALA C CA  1 
ATOM   7367  C C   . ALA C 1 64  ? -21.418 -22.918 -8.333  1.00 52.28  ? 64  ALA C C   1 
ATOM   7368  O O   . ALA C 1 64  ? -21.625 -21.721 -8.176  1.00 58.94  ? 64  ALA C O   1 
ATOM   7369  C CB  . ALA C 1 64  ? -18.978 -23.573 -8.146  1.00 38.61  ? 64  ALA C CB  1 
ATOM   7370  N N   . ALA C 1 65  ? -22.084 -23.653 -9.234  1.00 51.34  ? 65  ALA C N   1 
ATOM   7371  C CA  . ALA C 1 65  ? -22.987 -23.030 -10.195 1.00 50.02  ? 65  ALA C CA  1 
ATOM   7372  C C   . ALA C 1 65  ? -24.305 -22.641 -9.523  1.00 50.22  ? 65  ALA C C   1 
ATOM   7373  O O   . ALA C 1 65  ? -25.025 -21.820 -10.047 1.00 58.39  ? 65  ALA C O   1 
ATOM   7374  C CB  . ALA C 1 65  ? -23.220 -23.948 -11.377 1.00 51.26  ? 65  ALA C CB  1 
ATOM   7375  N N   . LEU C 1 66  ? -24.614 -23.243 -8.364  1.00 49.12  ? 66  LEU C N   1 
ATOM   7376  C CA  . LEU C 1 66  ? -25.776 -22.830 -7.571  1.00 44.11  ? 66  LEU C CA  1 
ATOM   7377  C C   . LEU C 1 66  ? -25.582 -21.376 -7.103  1.00 47.76  ? 66  LEU C C   1 
ATOM   7378  O O   . LEU C 1 66  ? -24.467 -20.856 -7.040  1.00 49.74  ? 66  LEU C O   1 
ATOM   7379  C CB  . LEU C 1 66  ? -25.967 -23.737 -6.354  1.00 47.72  ? 66  LEU C CB  1 
ATOM   7380  C CG  . LEU C 1 66  ? -26.448 -25.175 -6.594  1.00 48.42  ? 66  LEU C CG  1 
ATOM   7381  C CD1 . LEU C 1 66  ? -26.383 -25.907 -5.239  1.00 47.06  ? 66  LEU C CD1 1 
ATOM   7382  C CD2 . LEU C 1 66  ? -27.873 -25.268 -7.187  1.00 46.77  ? 66  LEU C CD2 1 
ATOM   7383  N N   . GLY C 1 67  ? -26.643 -20.769 -6.654  1.00 48.36  ? 67  GLY C N   1 
ATOM   7384  C CA  . GLY C 1 67  ? -26.550 -19.404 -6.189  1.00 53.69  ? 67  GLY C CA  1 
ATOM   7385  C C   . GLY C 1 67  ? -25.951 -19.317 -4.777  1.00 49.34  ? 67  GLY C C   1 
ATOM   7386  O O   . GLY C 1 67  ? -25.903 -20.302 -4.043  1.00 47.45  ? 67  GLY C O   1 
ATOM   7387  N N   . PRO C 1 68  ? -25.554 -18.109 -4.345  1.00 43.44  ? 68  PRO C N   1 
ATOM   7388  C CA  . PRO C 1 68  ? -25.125 -17.878 -2.970  1.00 43.72  ? 68  PRO C CA  1 
ATOM   7389  C C   . PRO C 1 68  ? -26.133 -18.292 -1.894  1.00 43.05  ? 68  PRO C C   1 
ATOM   7390  O O   . PRO C 1 68  ? -25.742 -18.777 -0.836  1.00 46.66  ? 68  PRO C O   1 
ATOM   7391  C CB  . PRO C 1 68  ? -24.858 -16.340 -2.946  1.00 42.63  ? 68  PRO C CB  1 
ATOM   7392  C CG  . PRO C 1 68  ? -24.624 -15.977 -4.393  1.00 45.56  ? 68  PRO C CG  1 
ATOM   7393  C CD  . PRO C 1 68  ? -25.499 -16.899 -5.175  1.00 44.35  ? 68  PRO C CD  1 
ATOM   7394  N N   . SER C 1 69  ? -27.422 -18.066 -2.152  1.00 38.94  ? 69  SER C N   1 
ATOM   7395  C CA  . SER C 1 69  ? -28.448 -18.289 -1.142  1.00 36.01  ? 69  SER C CA  1 
ATOM   7396  C C   . SER C 1 69  ? -28.616 -19.771 -0.901  1.00 36.27  ? 69  SER C C   1 
ATOM   7397  O O   . SER C 1 69  ? -28.863 -20.191 0.228   1.00 39.02  ? 69  SER C O   1 
ATOM   7398  C CB  . SER C 1 69  ? -29.763 -17.647 -1.527  1.00 38.53  ? 69  SER C CB  1 
ATOM   7399  O OG  . SER C 1 69  ? -29.619 -16.233 -1.598  1.00 43.62  ? 69  SER C OG  1 
ATOM   7400  N N   . ALA C 1 70  ? -28.483 -20.564 -1.968  1.00 36.62  ? 70  ALA C N   1 
ATOM   7401  C CA  . ALA C 1 70  ? -28.629 -22.003 -1.854  1.00 37.50  ? 70  ALA C CA  1 
ATOM   7402  C C   . ALA C 1 70  ? -27.500 -22.567 -0.987  1.00 43.57  ? 70  ALA C C   1 
ATOM   7403  O O   . ALA C 1 70  ? -27.756 -23.368 -0.086  1.00 48.47  ? 70  ALA C O   1 
ATOM   7404  C CB  . ALA C 1 70  ? -28.655 -22.632 -3.207  1.00 35.57  ? 70  ALA C CB  1 
ATOM   7405  N N   . ARG C 1 71  ? -26.261 -22.093 -1.221  1.00 38.98  ? 71  ARG C N   1 
ATOM   7406  C CA  . ARG C 1 71  ? -25.111 -22.582 -0.471  1.00 38.25  ? 71  ARG C CA  1 
ATOM   7407  C C   . ARG C 1 71  ? -25.192 -22.121 0.971   1.00 41.41  ? 71  ARG C C   1 
ATOM   7408  O O   . ARG C 1 71  ? -24.851 -22.884 1.892   1.00 41.74  ? 71  ARG C O   1 
ATOM   7409  C CB  . ARG C 1 71  ? -23.790 -22.159 -1.097  1.00 36.96  ? 71  ARG C CB  1 
ATOM   7410  C CG  . ARG C 1 71  ? -23.479 -22.951 -2.356  1.00 39.80  ? 71  ARG C CG  1 
ATOM   7411  C CD  . ARG C 1 71  ? -22.072 -22.726 -2.885  1.00 41.67  ? 71  ARG C CD  1 
ATOM   7412  N NE  . ARG C 1 71  ? -22.098 -21.914 -4.111  1.00 41.66  ? 71  ARG C NE  1 
ATOM   7413  C CZ  . ARG C 1 71  ? -21.892 -20.618 -4.160  1.00 41.80  ? 71  ARG C CZ  1 
ATOM   7414  N NH1 . ARG C 1 71  ? -21.694 -19.946 -3.069  1.00 44.37  ? 71  ARG C NH1 1 
ATOM   7415  N NH2 . ARG C 1 71  ? -21.908 -19.988 -5.309  1.00 48.96  ? 71  ARG C NH2 1 
ATOM   7416  N N   . ALA C 1 72  ? -25.666 -20.885 1.175   1.00 38.56  ? 72  ALA C N   1 
ATOM   7417  C CA  . ALA C 1 72  ? -25.784 -20.345 2.519   1.00 39.80  ? 72  ALA C CA  1 
ATOM   7418  C C   . ALA C 1 72  ? -26.841 -21.131 3.326   1.00 38.99  ? 72  ALA C C   1 
ATOM   7419  O O   . ALA C 1 72  ? -26.723 -21.258 4.541   1.00 39.28  ? 72  ALA C O   1 
ATOM   7420  C CB  . ALA C 1 72  ? -26.118 -18.873 2.458   1.00 37.92  ? 72  ALA C CB  1 
ATOM   7421  N N   . ALA C 1 73  ? -27.871 -21.644 2.642   1.00 35.34  ? 73  ALA C N   1 
ATOM   7422  C CA  . ALA C 1 73  ? -28.955 -22.351 3.318   1.00 40.31  ? 73  ALA C CA  1 
ATOM   7423  C C   . ALA C 1 73  ? -28.407 -23.576 4.058   1.00 40.97  ? 73  ALA C C   1 
ATOM   7424  O O   . ALA C 1 73  ? -28.836 -23.868 5.191   1.00 41.84  ? 73  ALA C O   1 
ATOM   7425  C CB  . ALA C 1 73  ? -30.030 -22.753 2.328   1.00 39.35  ? 73  ALA C CB  1 
ATOM   7426  N N   . VAL C 1 74  ? -27.478 -24.296 3.400   1.00 39.35  ? 74  VAL C N   1 
ATOM   7427  C CA  . VAL C 1 74  ? -26.914 -25.521 3.943   1.00 39.07  ? 74  VAL C CA  1 
ATOM   7428  C C   . VAL C 1 74  ? -26.159 -25.192 5.230   1.00 39.68  ? 74  VAL C C   1 
ATOM   7429  O O   . VAL C 1 74  ? -26.284 -25.902 6.210   1.00 45.15  ? 74  VAL C O   1 
ATOM   7430  C CB  . VAL C 1 74  ? -26.008 -26.235 2.920   1.00 40.32  ? 74  VAL C CB  1 
ATOM   7431  C CG1 . VAL C 1 74  ? -25.248 -27.403 3.542   1.00 41.39  ? 74  VAL C CG1 1 
ATOM   7432  C CG2 . VAL C 1 74  ? -26.799 -26.704 1.711   1.00 37.86  ? 74  VAL C CG2 1 
ATOM   7433  N N   . LEU C 1 75  ? -25.431 -24.079 5.239   1.00 38.18  ? 75  LEU C N   1 
ATOM   7434  C CA  . LEU C 1 75  ? -24.683 -23.700 6.418   1.00 39.34  ? 75  LEU C CA  1 
ATOM   7435  C C   . LEU C 1 75  ? -25.621 -23.275 7.538   1.00 40.47  ? 75  LEU C C   1 
ATOM   7436  O O   . LEU C 1 75  ? -25.350 -23.576 8.695   1.00 44.59  ? 75  LEU C O   1 
ATOM   7437  C CB  . LEU C 1 75  ? -23.642 -22.642 6.111   1.00 42.28  ? 75  LEU C CB  1 
ATOM   7438  C CG  . LEU C 1 75  ? -22.278 -23.207 5.688   1.00 49.63  ? 75  LEU C CG  1 
ATOM   7439  C CD1 . LEU C 1 75  ? -22.239 -23.451 4.187   1.00 49.94  ? 75  LEU C CD1 1 
ATOM   7440  C CD2 . LEU C 1 75  ? -21.137 -22.334 6.114   1.00 53.77  ? 75  LEU C CD2 1 
ATOM   7441  N N   . TYR C 1 76  ? -26.759 -22.648 7.194   1.00 43.89  ? 76  TYR C N   1 
ATOM   7442  C CA  . TYR C 1 76  ? -27.763 -22.270 8.210   1.00 41.03  ? 76  TYR C CA  1 
ATOM   7443  C C   . TYR C 1 76  ? -28.359 -23.537 8.835   1.00 37.81  ? 76  TYR C C   1 
ATOM   7444  O O   . TYR C 1 76  ? -28.583 -23.591 10.033  1.00 34.01  ? 76  TYR C O   1 
ATOM   7445  C CB  . TYR C 1 76  ? -28.866 -21.384 7.612   1.00 39.18  ? 76  TYR C CB  1 
ATOM   7446  C CG  . TYR C 1 76  ? -28.484 -19.921 7.408   1.00 35.51  ? 76  TYR C CG  1 
ATOM   7447  C CD1 . TYR C 1 76  ? -28.086 -19.122 8.482   1.00 35.67  ? 76  TYR C CD1 1 
ATOM   7448  C CD2 . TYR C 1 76  ? -28.503 -19.345 6.146   1.00 32.57  ? 76  TYR C CD2 1 
ATOM   7449  C CE1 . TYR C 1 76  ? -27.714 -17.800 8.300   1.00 32.35  ? 76  TYR C CE1 1 
ATOM   7450  C CE2 . TYR C 1 76  ? -28.166 -18.016 5.955   1.00 32.60  ? 76  TYR C CE2 1 
ATOM   7451  C CZ  . TYR C 1 76  ? -27.753 -17.245 7.034   1.00 32.76  ? 76  TYR C CZ  1 
ATOM   7452  O OH  . TYR C 1 76  ? -27.372 -15.942 6.847   1.00 32.17  ? 76  TYR C OH  1 
ATOM   7453  N N   . LYS C 1 77  ? -28.596 -24.561 8.003   1.00 40.64  ? 77  LYS C N   1 
ATOM   7454  C CA  . LYS C 1 77  ? -29.130 -25.833 8.489   1.00 46.02  ? 77  LYS C CA  1 
ATOM   7455  C C   . LYS C 1 77  ? -28.090 -26.552 9.362   1.00 46.71  ? 77  LYS C C   1 
ATOM   7456  O O   . LYS C 1 77  ? -28.454 -27.299 10.274  1.00 43.73  ? 77  LYS C O   1 
ATOM   7457  C CB  . LYS C 1 77  ? -29.592 -26.711 7.317   1.00 48.11  ? 77  LYS C CB  1 
ATOM   7458  C CG  . LYS C 1 77  ? -30.943 -26.292 6.702   1.00 52.45  ? 77  LYS C CG  1 
ATOM   7459  C CD  . LYS C 1 77  ? -31.505 -27.227 5.619   1.00 63.16  ? 77  LYS C CD  1 
ATOM   7460  C CE  . LYS C 1 77  ? -31.367 -26.677 4.184   1.00 71.69  ? 77  LYS C CE  1 
ATOM   7461  N NZ  . LYS C 1 77  ? -31.377 -27.727 3.143   1.00 63.55  ? 77  LYS C NZ  1 
ATOM   7462  N N   . ALA C 1 78  ? -26.792 -26.338 9.078   1.00 39.43  ? 78  ALA C N   1 
ATOM   7463  C CA  . ALA C 1 78  ? -25.754 -27.014 9.833   1.00 35.76  ? 78  ALA C CA  1 
ATOM   7464  C C   . ALA C 1 78  ? -25.685 -26.464 11.272  1.00 37.86  ? 78  ALA C C   1 
ATOM   7465  O O   . ALA C 1 78  ? -25.435 -27.229 12.217  1.00 35.00  ? 78  ALA C O   1 
ATOM   7466  C CB  . ALA C 1 78  ? -24.445 -26.903 9.126   1.00 35.34  ? 78  ALA C CB  1 
ATOM   7467  N N   . VAL C 1 79  ? -25.913 -25.146 11.437  1.00 36.14  ? 79  VAL C N   1 
ATOM   7468  C CA  . VAL C 1 79  ? -25.937 -24.517 12.769  1.00 38.56  ? 79  VAL C CA  1 
ATOM   7469  C C   . VAL C 1 79  ? -27.061 -25.155 13.581  1.00 41.33  ? 79  VAL C C   1 
ATOM   7470  O O   . VAL C 1 79  ? -26.991 -25.324 14.806  1.00 43.78  ? 79  VAL C O   1 
ATOM   7471  C CB  . VAL C 1 79  ? -26.190 -23.002 12.614  1.00 38.43  ? 79  VAL C CB  1 
ATOM   7472  C CG1 . VAL C 1 79  ? -26.225 -22.286 13.955  1.00 40.88  ? 79  VAL C CG1 1 
ATOM   7473  C CG2 . VAL C 1 79  ? -25.201 -22.344 11.688  1.00 38.74  ? 79  VAL C CG2 1 
ATOM   7474  N N   . GLU C 1 80  ? -28.131 -25.340 12.862  1.00 49.58  ? 80  GLU C N   1 
ATOM   7475  C CA  . GLU C 1 80  ? -29.374 -25.941 13.287  1.00 61.24  ? 80  GLU C CA  1 
ATOM   7476  C C   . GLU C 1 80  ? -29.102 -27.307 13.949  1.00 58.24  ? 80  GLU C C   1 
ATOM   7477  O O   . GLU C 1 80  ? -29.609 -27.590 15.046  1.00 53.63  ? 80  GLU C O   1 
ATOM   7478  C CB  . GLU C 1 80  ? -30.194 -26.036 11.968  1.00 84.31  ? 80  GLU C CB  1 
ATOM   7479  C CG  . GLU C 1 80  ? -30.896 -24.728 11.530  1.00 99.39  ? 80  GLU C CG  1 
ATOM   7480  C CD  . GLU C 1 80  ? -32.407 -24.635 11.770  1.00 107.04 ? 80  GLU C CD  1 
ATOM   7481  O OE1 . GLU C 1 80  ? -33.149 -25.568 11.369  1.00 115.19 ? 80  GLU C OE1 1 
ATOM   7482  O OE2 . GLU C 1 80  ? -32.849 -23.586 12.297  1.00 116.95 ? 80  GLU C OE2 1 
ATOM   7483  N N   . VAL C 1 81  ? -28.288 -28.142 13.248  1.00 47.38  ? 81  VAL C N   1 
ATOM   7484  C CA  . VAL C 1 81  ? -27.849 -29.453 13.724  1.00 40.24  ? 81  VAL C CA  1 
ATOM   7485  C C   . VAL C 1 81  ? -26.917 -29.302 14.930  1.00 40.37  ? 81  VAL C C   1 
ATOM   7486  O O   . VAL C 1 81  ? -26.929 -30.136 15.831  1.00 43.84  ? 81  VAL C O   1 
ATOM   7487  C CB  . VAL C 1 81  ? -27.124 -30.209 12.602  1.00 39.94  ? 81  VAL C CB  1 
ATOM   7488  C CG1 . VAL C 1 81  ? -26.614 -31.555 13.080  1.00 39.11  ? 81  VAL C CG1 1 
ATOM   7489  C CG2 . VAL C 1 81  ? -27.983 -30.359 11.349  1.00 39.23  ? 81  VAL C CG2 1 
ATOM   7490  N N   . PHE C 1 82  ? -26.054 -28.287 14.900  1.00 35.77  ? 82  PHE C N   1 
ATOM   7491  C CA  . PHE C 1 82  ? -25.152 -28.028 16.023  1.00 37.62  ? 82  PHE C CA  1 
ATOM   7492  C C   . PHE C 1 82  ? -25.947 -27.924 17.347  1.00 39.98  ? 82  PHE C C   1 
ATOM   7493  O O   . PHE C 1 82  ? -25.449 -28.322 18.414  1.00 38.22  ? 82  PHE C O   1 
ATOM   7494  C CB  . PHE C 1 82  ? -24.308 -26.771 15.776  1.00 35.61  ? 82  PHE C CB  1 
ATOM   7495  C CG  . PHE C 1 82  ? -22.893 -27.070 15.306  1.00 33.90  ? 82  PHE C CG  1 
ATOM   7496  C CD1 . PHE C 1 82  ? -22.607 -27.254 13.955  1.00 33.98  ? 82  PHE C CD1 1 
ATOM   7497  C CD2 . PHE C 1 82  ? -21.855 -27.216 16.216  1.00 35.29  ? 82  PHE C CD2 1 
ATOM   7498  C CE1 . PHE C 1 82  ? -21.314 -27.574 13.531  1.00 34.27  ? 82  PHE C CE1 1 
ATOM   7499  C CE2 . PHE C 1 82  ? -20.568 -27.542 15.784  1.00 35.66  ? 82  PHE C CE2 1 
ATOM   7500  C CZ  . PHE C 1 82  ? -20.305 -27.704 14.442  1.00 33.93  ? 82  PHE C CZ  1 
ATOM   7501  N N   . ASP C 1 83  ? -27.154 -27.360 17.280  1.00 41.60  ? 83  ASP C N   1 
ATOM   7502  C CA  . ASP C 1 83  ? -27.937 -27.084 18.480  1.00 44.80  ? 83  ASP C CA  1 
ATOM   7503  C C   . ASP C 1 83  ? -28.628 -28.354 18.955  1.00 42.92  ? 83  ASP C C   1 
ATOM   7504  O O   . ASP C 1 83  ? -28.608 -28.657 20.133  1.00 51.42  ? 83  ASP C O   1 
ATOM   7505  C CB  . ASP C 1 83  ? -28.899 -25.937 18.256  1.00 43.23  ? 83  ASP C CB  1 
ATOM   7506  C CG  . ASP C 1 83  ? -28.225 -24.576 18.110  1.00 50.67  ? 83  ASP C CG  1 
ATOM   7507  O OD1 . ASP C 1 83  ? -27.187 -24.368 18.776  1.00 44.46  ? 83  ASP C OD1 1 
ATOM   7508  O OD2 . ASP C 1 83  ? -28.744 -23.728 17.331  1.00 52.11  ? 83  ASP C OD2 1 
ATOM   7509  N N   . ARG C 1 84  ? -29.198 -29.105 18.023  1.00 43.58  ? 84  ARG C N   1 
ATOM   7510  C CA  . ARG C 1 84  ? -29.955 -30.295 18.363  1.00 47.10  ? 84  ARG C CA  1 
ATOM   7511  C C   . ARG C 1 84  ? -29.023 -31.346 18.973  1.00 46.86  ? 84  ARG C C   1 
ATOM   7512  O O   . ARG C 1 84  ? -29.399 -32.010 19.925  1.00 59.36  ? 84  ARG C O   1 
ATOM   7513  C CB  . ARG C 1 84  ? -30.665 -30.860 17.131  1.00 50.00  ? 84  ARG C CB  1 
ATOM   7514  C CG  . ARG C 1 84  ? -31.777 -29.973 16.595  1.00 50.00  ? 84  ARG C CG  1 
ATOM   7515  C CD  . ARG C 1 84  ? -32.514 -30.555 15.399  1.00 50.00  ? 84  ARG C CD  1 
ATOM   7516  N NE  . ARG C 1 84  ? -33.524 -29.638 14.879  1.00 50.00  ? 84  ARG C NE  1 
ATOM   7517  C CZ  . ARG C 1 84  ? -34.226 -29.852 13.775  1.00 50.00  ? 84  ARG C CZ  1 
ATOM   7518  N NH1 . ARG C 1 84  ? -34.035 -30.959 13.069  1.00 50.00  ? 84  ARG C NH1 1 
ATOM   7519  N NH2 . ARG C 1 84  ? -35.124 -28.962 13.375  1.00 50.00  ? 84  ARG C NH2 1 
ATOM   7520  N N   . ARG C 1 85  ? -27.790 -31.462 18.436  1.00 45.90  ? 85  ARG C N   1 
ATOM   7521  C CA  . ARG C 1 85  ? -26.875 -32.532 18.830  1.00 38.98  ? 85  ARG C CA  1 
ATOM   7522  C C   . ARG C 1 85  ? -25.752 -31.986 19.694  1.00 41.68  ? 85  ARG C C   1 
ATOM   7523  O O   . ARG C 1 85  ? -24.669 -32.586 19.738  1.00 42.33  ? 85  ARG C O   1 
ATOM   7524  C CB  . ARG C 1 85  ? -26.295 -33.229 17.618  1.00 35.34  ? 85  ARG C CB  1 
ATOM   7525  C CG  . ARG C 1 85  ? -27.354 -33.623 16.608  1.00 39.70  ? 85  ARG C CG  1 
ATOM   7526  C CD  . ARG C 1 85  ? -26.770 -34.487 15.476  1.00 42.86  ? 85  ARG C CD  1 
ATOM   7527  N NE  . ARG C 1 85  ? -27.802 -35.170 14.687  1.00 39.20  ? 85  ARG C NE  1 
ATOM   7528  C CZ  . ARG C 1 85  ? -28.208 -36.396 14.922  1.00 39.03  ? 85  ARG C CZ  1 
ATOM   7529  N NH1 . ARG C 1 85  ? -27.666 -37.100 15.912  1.00 42.34  ? 85  ARG C NH1 1 
ATOM   7530  N NH2 . ARG C 1 85  ? -29.182 -36.901 14.213  1.00 38.35  ? 85  ARG C NH2 1 
ATOM   7531  N N   . HIS C 1 86  ? -26.053 -30.913 20.462  1.00 41.57  ? 86  HIS C N   1 
ATOM   7532  C CA  . HIS C 1 86  ? -25.042 -30.207 21.264  1.00 41.85  ? 86  HIS C CA  1 
ATOM   7533  C C   . HIS C 1 86  ? -24.273 -31.204 22.142  1.00 44.72  ? 86  HIS C C   1 
ATOM   7534  O O   . HIS C 1 86  ? -23.054 -31.307 22.039  1.00 44.26  ? 86  HIS C O   1 
ATOM   7535  C CB  . HIS C 1 86  ? -25.699 -29.085 22.090  1.00 38.11  ? 86  HIS C CB  1 
ATOM   7536  C CG  . HIS C 1 86  ? -24.763 -28.263 22.924  1.00 37.92  ? 86  HIS C CG  1 
ATOM   7537  N ND1 . HIS C 1 86  ? -25.148 -27.053 23.458  1.00 40.45  ? 86  HIS C ND1 1 
ATOM   7538  C CD2 . HIS C 1 86  ? -23.507 -28.451 23.336  1.00 46.79  ? 86  HIS C CD2 1 
ATOM   7539  C CE1 . HIS C 1 86  ? -24.145 -26.525 24.161  1.00 41.36  ? 86  HIS C CE1 1 
ATOM   7540  N NE2 . HIS C 1 86  ? -23.142 -27.342 24.112  1.00 44.77  ? 86  HIS C NE2 1 
ATOM   7541  N N   . GLU C 1 87  ? -24.997 -31.887 23.044  1.00 49.71  ? 87  GLU C N   1 
ATOM   7542  C CA  . GLU C 1 87  ? -24.374 -32.762 24.037  1.00 48.53  ? 87  GLU C CA  1 
ATOM   7543  C C   . GLU C 1 87  ? -23.684 -33.943 23.336  1.00 47.01  ? 87  GLU C C   1 
ATOM   7544  O O   . GLU C 1 87  ? -22.594 -34.362 23.747  1.00 43.04  ? 87  GLU C O   1 
ATOM   7545  C CB  . GLU C 1 87  ? -25.396 -33.268 25.063  1.00 50.79  ? 87  GLU C CB  1 
ATOM   7546  C CG  . GLU C 1 87  ? -24.817 -34.276 26.064  1.00 50.76  ? 87  GLU C CG  1 
ATOM   7547  C CD  . GLU C 1 87  ? -23.582 -33.794 26.814  1.00 56.58  ? 87  GLU C CD  1 
ATOM   7548  O OE1 . GLU C 1 87  ? -23.424 -32.556 26.955  1.00 64.44  ? 87  GLU C OE1 1 
ATOM   7549  O OE2 . GLU C 1 87  ? -22.753 -34.647 27.230  1.00 56.36  ? 87  GLU C OE2 1 
ATOM   7550  N N   . GLU C 1 88  ? -24.324 -34.470 22.273  1.00 41.04  ? 88  GLU C N   1 
ATOM   7551  C CA  . GLU C 1 88  ? -23.745 -35.564 21.492  1.00 40.78  ? 88  GLU C CA  1 
ATOM   7552  C C   . GLU C 1 88  ? -22.339 -35.155 21.006  1.00 46.00  ? 88  GLU C C   1 
ATOM   7553  O O   . GLU C 1 88  ? -21.393 -35.930 21.105  1.00 48.11  ? 88  GLU C O   1 
ATOM   7554  C CB  . GLU C 1 88  ? -24.692 -35.933 20.341  1.00 38.22  ? 88  GLU C CB  1 
ATOM   7555  C CG  . GLU C 1 88  ? -24.079 -36.894 19.322  1.00 40.79  ? 88  GLU C CG  1 
ATOM   7556  C CD  . GLU C 1 88  ? -25.032 -37.336 18.210  1.00 41.49  ? 88  GLU C CD  1 
ATOM   7557  O OE1 . GLU C 1 88  ? -26.099 -36.705 18.076  1.00 42.05  ? 88  GLU C OE1 1 
ATOM   7558  O OE2 . GLU C 1 88  ? -24.724 -38.329 17.487  1.00 39.59  ? 88  GLU C OE2 1 
ATOM   7559  N N   . ILE C 1 89  ? -22.218 -33.913 20.498  1.00 45.96  ? 89  ILE C N   1 
ATOM   7560  C CA  . ILE C 1 89  ? -20.961 -33.427 19.949  1.00 39.38  ? 89  ILE C CA  1 
ATOM   7561  C C   . ILE C 1 89  ? -19.938 -33.278 21.078  1.00 38.29  ? 89  ILE C C   1 
ATOM   7562  O O   . ILE C 1 89  ? -18.797 -33.727 20.950  1.00 44.00  ? 89  ILE C O   1 
ATOM   7563  C CB  . ILE C 1 89  ? -21.175 -32.112 19.176  1.00 38.63  ? 89  ILE C CB  1 
ATOM   7564  C CG1 . ILE C 1 89  ? -22.033 -32.333 17.925  1.00 39.24  ? 89  ILE C CG1 1 
ATOM   7565  C CG2 . ILE C 1 89  ? -19.841 -31.452 18.820  1.00 39.78  ? 89  ILE C CG2 1 
ATOM   7566  C CD1 . ILE C 1 89  ? -22.717 -31.066 17.409  1.00 36.60  ? 89  ILE C CD1 1 
ATOM   7567  N N   . VAL C 1 90  ? -20.341 -32.635 22.174  1.00 36.61  ? 90  VAL C N   1 
ATOM   7568  C CA  . VAL C 1 90  ? -19.423 -32.362 23.283  1.00 40.34  ? 90  VAL C CA  1 
ATOM   7569  C C   . VAL C 1 90  ? -18.915 -33.695 23.882  1.00 39.69  ? 90  VAL C C   1 
ATOM   7570  O O   . VAL C 1 90  ? -17.750 -33.812 24.229  1.00 38.32  ? 90  VAL C O   1 
ATOM   7571  C CB  . VAL C 1 90  ? -20.083 -31.471 24.363  1.00 43.14  ? 90  VAL C CB  1 
ATOM   7572  C CG1 . VAL C 1 90  ? -19.374 -31.575 25.709  1.00 43.95  ? 90  VAL C CG1 1 
ATOM   7573  C CG2 . VAL C 1 90  ? -20.173 -30.008 23.924  1.00 41.15  ? 90  VAL C CG2 1 
ATOM   7574  N N   . ASP C 1 91  ? -19.792 -34.690 23.984  1.00 41.36  ? 91  ASP C N   1 
ATOM   7575  C CA  . ASP C 1 91  ? -19.405 -35.988 24.521  1.00 44.67  ? 91  ASP C CA  1 
ATOM   7576  C C   . ASP C 1 91  ? -18.329 -36.629 23.638  1.00 45.85  ? 91  ASP C C   1 
ATOM   7577  O O   . ASP C 1 91  ? -17.370 -37.224 24.161  1.00 46.86  ? 91  ASP C O   1 
ATOM   7578  C CB  . ASP C 1 91  ? -20.596 -36.916 24.690  1.00 48.89  ? 91  ASP C CB  1 
ATOM   7579  C CG  . ASP C 1 91  ? -20.314 -38.220 25.442  1.00 57.17  ? 91  ASP C CG  1 
ATOM   7580  O OD1 . ASP C 1 91  ? -19.529 -38.191 26.446  1.00 55.14  ? 91  ASP C OD1 1 
ATOM   7581  O OD2 . ASP C 1 91  ? -20.898 -39.255 25.050  1.00 73.41  ? 91  ASP C OD2 1 
ATOM   7582  N N   . TRP C 1 92  ? -18.497 -36.531 22.300  1.00 38.46  ? 92  TRP C N   1 
ATOM   7583  C CA  . TRP C 1 92  ? -17.540 -37.126 21.366  1.00 36.34  ? 92  TRP C CA  1 
ATOM   7584  C C   . TRP C 1 92  ? -16.172 -36.470 21.526  1.00 39.40  ? 92  TRP C C   1 
ATOM   7585  O O   . TRP C 1 92  ? -15.143 -37.142 21.496  1.00 37.45  ? 92  TRP C O   1 
ATOM   7586  C CB  . TRP C 1 92  ? -18.037 -37.023 19.925  1.00 39.67  ? 92  TRP C CB  1 
ATOM   7587  C CG  . TRP C 1 92  ? -18.703 -38.285 19.425  1.00 41.55  ? 92  TRP C CG  1 
ATOM   7588  C CD1 . TRP C 1 92  ? -20.008 -38.454 19.063  1.00 37.44  ? 92  TRP C CD1 1 
ATOM   7589  C CD2 . TRP C 1 92  ? -18.070 -39.573 19.256  1.00 41.48  ? 92  TRP C CD2 1 
ATOM   7590  N NE1 . TRP C 1 92  ? -20.236 -39.758 18.682  1.00 38.08  ? 92  TRP C NE1 1 
ATOM   7591  C CE2 . TRP C 1 92  ? -19.064 -40.466 18.790  1.00 42.88  ? 92  TRP C CE2 1 
ATOM   7592  C CE3 . TRP C 1 92  ? -16.770 -40.050 19.460  1.00 45.51  ? 92  TRP C CE3 1 
ATOM   7593  C CZ2 . TRP C 1 92  ? -18.789 -41.807 18.514  1.00 47.17  ? 92  TRP C CZ2 1 
ATOM   7594  C CZ3 . TRP C 1 92  ? -16.495 -41.373 19.178  1.00 51.35  ? 92  TRP C CZ3 1 
ATOM   7595  C CH2 . TRP C 1 92  ? -17.493 -42.239 18.709  1.00 50.03  ? 92  TRP C CH2 1 
ATOM   7596  N N   . ILE C 1 93  ? -16.168 -35.170 21.768  1.00 40.09  ? 93  ILE C N   1 
ATOM   7597  C CA  . ILE C 1 93  ? -14.921 -34.433 21.903  1.00 39.60  ? 93  ILE C CA  1 
ATOM   7598  C C   . ILE C 1 93  ? -14.174 -34.931 23.143  1.00 37.91  ? 93  ILE C C   1 
ATOM   7599  O O   . ILE C 1 93  ? -12.970 -35.125 23.102  1.00 37.52  ? 93  ILE C O   1 
ATOM   7600  C CB  . ILE C 1 93  ? -15.185 -32.904 21.945  1.00 35.21  ? 93  ILE C CB  1 
ATOM   7601  C CG1 . ILE C 1 93  ? -15.779 -32.400 20.607  1.00 35.86  ? 93  ILE C CG1 1 
ATOM   7602  C CG2 . ILE C 1 93  ? -13.921 -32.145 22.330  1.00 32.25  ? 93  ILE C CG2 1 
ATOM   7603  C CD1 . ILE C 1 93  ? -16.163 -30.931 20.608  1.00 35.75  ? 93  ILE C CD1 1 
ATOM   7604  N N   . ILE C 1 94  ? -14.897 -35.098 24.249  1.00 43.08  ? 94  ILE C N   1 
ATOM   7605  C CA  . ILE C 1 94  ? -14.290 -35.540 25.505  1.00 44.64  ? 94  ILE C CA  1 
ATOM   7606  C C   . ILE C 1 94  ? -13.729 -36.957 25.334  1.00 41.48  ? 94  ILE C C   1 
ATOM   7607  O O   . ILE C 1 94  ? -12.577 -37.200 25.654  1.00 43.82  ? 94  ILE C O   1 
ATOM   7608  C CB  . ILE C 1 94  ? -15.293 -35.481 26.662  1.00 44.97  ? 94  ILE C CB  1 
ATOM   7609  C CG1 . ILE C 1 94  ? -15.841 -34.053 26.885  1.00 49.38  ? 94  ILE C CG1 1 
ATOM   7610  C CG2 . ILE C 1 94  ? -14.668 -36.052 27.930  1.00 43.07  ? 94  ILE C CG2 1 
ATOM   7611  C CD1 . ILE C 1 94  ? -17.140 -34.005 27.699  1.00 52.71  ? 94  ILE C CD1 1 
ATOM   7612  N N   . ARG C 1 95  ? -14.553 -37.869 24.813  1.00 40.37  ? 95  ARG C N   1 
ATOM   7613  C CA  . ARG C 1 95  ? -14.206 -39.290 24.762  1.00 47.54  ? 95  ARG C CA  1 
ATOM   7614  C C   . ARG C 1 95  ? -13.014 -39.539 23.818  1.00 45.75  ? 95  ARG C C   1 
ATOM   7615  O O   . ARG C 1 95  ? -12.057 -40.206 24.197  1.00 41.13  ? 95  ARG C O   1 
ATOM   7616  C CB  . ARG C 1 95  ? -15.420 -40.126 24.348  1.00 52.45  ? 95  ARG C CB  1 
ATOM   7617  C CG  . ARG C 1 95  ? -16.254 -40.603 25.534  1.00 50.65  ? 95  ARG C CG  1 
ATOM   7618  C CD  . ARG C 1 95  ? -17.745 -40.678 25.216  1.00 54.55  ? 95  ARG C CD  1 
ATOM   7619  N NE  . ARG C 1 95  ? -18.095 -41.824 24.355  1.00 64.61  ? 95  ARG C NE  1 
ATOM   7620  C CZ  . ARG C 1 95  ? -18.779 -41.768 23.184  1.00 76.09  ? 95  ARG C CZ  1 
ATOM   7621  N NH1 . ARG C 1 95  ? -19.313 -40.622 22.756  1.00 81.64  ? 95  ARG C NH1 1 
ATOM   7622  N NH2 . ARG C 1 95  ? -18.937 -42.870 22.460  1.00 76.64  ? 95  ARG C NH2 1 
ATOM   7623  N N   . GLU C 1 96  ? -13.067 -38.991 22.600  1.00 42.23  ? 96  GLU C N   1 
ATOM   7624  C CA  . GLU C 1 96  ? -12.039 -39.276 21.601  1.00 41.35  ? 96  GLU C CA  1 
ATOM   7625  C C   . GLU C 1 96  ? -10.746 -38.502 21.908  1.00 38.51  ? 96  GLU C C   1 
ATOM   7626  O O   . GLU C 1 96  ? -9.676  -39.082 21.901  1.00 39.22  ? 96  GLU C O   1 
ATOM   7627  C CB  . GLU C 1 96  ? -12.547 -38.980 20.197  1.00 47.34  ? 96  GLU C CB  1 
ATOM   7628  C CG  . GLU C 1 96  ? -11.666 -39.564 19.103  1.00 50.28  ? 96  GLU C CG  1 
ATOM   7629  C CD  . GLU C 1 96  ? -12.152 -39.234 17.713  1.00 54.67  ? 96  GLU C CD  1 
ATOM   7630  O OE1 . GLU C 1 96  ? -12.540 -38.054 17.493  1.00 50.35  ? 96  GLU C OE1 1 
ATOM   7631  O OE2 . GLU C 1 96  ? -12.141 -40.148 16.841  1.00 52.76  ? 96  GLU C OE2 1 
ATOM   7632  N N   . SER C 1 97  ? -10.849 -37.191 22.170  1.00 41.01  ? 97  SER C N   1 
ATOM   7633  C CA  . SER C 1 97  ? -9.660  -36.327 22.272  1.00 45.13  ? 97  SER C CA  1 
ATOM   7634  C C   . SER C 1 97  ? -9.117  -36.308 23.706  1.00 46.13  ? 97  SER C C   1 
ATOM   7635  O O   . SER C 1 97  ? -7.954  -35.954 23.928  1.00 44.45  ? 97  SER C O   1 
ATOM   7636  C CB  . SER C 1 97  ? -9.956  -34.914 21.798  1.00 46.73  ? 97  SER C CB  1 
ATOM   7637  O OG  . SER C 1 97  ? -10.866 -34.258 22.669  1.00 46.33  ? 97  SER C OG  1 
ATOM   7638  N N   . GLY C 1 98  ? -9.988  -36.638 24.675  1.00 46.55  ? 98  GLY C N   1 
ATOM   7639  C CA  . GLY C 1 98  ? -9.651  -36.550 26.097  1.00 47.98  ? 98  GLY C CA  1 
ATOM   7640  C C   . GLY C 1 98  ? -9.707  -35.109 26.632  1.00 48.78  ? 98  GLY C C   1 
ATOM   7641  O O   . GLY C 1 98  ? -9.178  -34.826 27.699  1.00 53.41  ? 98  GLY C O   1 
ATOM   7642  N N   . SER C 1 99  ? -10.353 -34.213 25.876  1.00 46.27  ? 99  SER C N   1 
ATOM   7643  C CA  . SER C 1 99  ? -10.546 -32.822 26.282  1.00 45.76  ? 99  SER C CA  1 
ATOM   7644  C C   . SER C 1 99  ? -11.491 -32.735 27.499  1.00 39.49  ? 99  SER C C   1 
ATOM   7645  O O   . SER C 1 99  ? -12.459 -33.492 27.602  1.00 41.41  ? 99  SER C O   1 
ATOM   7646  C CB  . SER C 1 99  ? -11.083 -31.996 25.087  1.00 50.24  ? 99  SER C CB  1 
ATOM   7647  O OG  . SER C 1 99  ? -11.596 -30.742 25.503  1.00 53.78  ? 99  SER C OG  1 
ATOM   7648  N N   . THR C 1 100 ? -11.245 -31.764 28.383  1.00 38.67  ? 100 THR C N   1 
ATOM   7649  C CA  . THR C 1 100 ? -12.167 -31.497 29.501  1.00 37.50  ? 100 THR C CA  1 
ATOM   7650  C C   . THR C 1 100 ? -13.511 -31.010 28.958  1.00 42.84  ? 100 THR C C   1 
ATOM   7651  O O   . THR C 1 100 ? -13.591 -30.452 27.849  1.00 47.46  ? 100 THR C O   1 
ATOM   7652  C CB  . THR C 1 100 ? -11.579 -30.473 30.474  1.00 37.03  ? 100 THR C CB  1 
ATOM   7653  O OG1 . THR C 1 100 ? -11.359 -29.244 29.759  1.00 37.34  ? 100 THR C OG1 1 
ATOM   7654  C CG2 . THR C 1 100 ? -10.289 -30.954 31.098  1.00 36.30  ? 100 THR C CG2 1 
ATOM   7655  N N   . ARG C 1 101 ? -14.560 -31.204 29.776  1.00 42.36  ? 101 ARG C N   1 
ATOM   7656  C CA  . ARG C 1 101 ? -15.916 -30.762 29.463  1.00 39.21  ? 101 ARG C CA  1 
ATOM   7657  C C   . ARG C 1 101 ? -15.929 -29.251 29.229  1.00 41.84  ? 101 ARG C C   1 
ATOM   7658  O O   . ARG C 1 101 ? -16.610 -28.772 28.348  1.00 42.72  ? 101 ARG C O   1 
ATOM   7659  C CB  . ARG C 1 101 ? -16.865 -31.146 30.611  1.00 40.41  ? 101 ARG C CB  1 
ATOM   7660  C CG  . ARG C 1 101 ? -18.347 -30.970 30.320  1.00 41.21  ? 101 ARG C CG  1 
ATOM   7661  C CD  . ARG C 1 101 ? -19.218 -31.861 31.211  1.00 42.68  ? 101 ARG C CD  1 
ATOM   7662  N NE  . ARG C 1 101 ? -19.508 -33.169 30.605  1.00 44.38  ? 101 ARG C NE  1 
ATOM   7663  C CZ  . ARG C 1 101 ? -20.403 -33.361 29.644  1.00 49.44  ? 101 ARG C CZ  1 
ATOM   7664  N NH1 . ARG C 1 101 ? -21.129 -32.351 29.194  1.00 51.40  ? 101 ARG C NH1 1 
ATOM   7665  N NH2 . ARG C 1 101 ? -20.553 -34.551 29.112  1.00 51.31  ? 101 ARG C NH2 1 
ATOM   7666  N N   . LEU C 1 102 ? -15.161 -28.520 30.029  1.00 42.64  ? 102 LEU C N   1 
ATOM   7667  C CA  . LEU C 1 102 ? -15.087 -27.080 29.916  1.00 47.17  ? 102 LEU C CA  1 
ATOM   7668  C C   . LEU C 1 102 ? -14.494 -26.698 28.550  1.00 42.81  ? 102 LEU C C   1 
ATOM   7669  O O   . LEU C 1 102 ? -15.039 -25.880 27.840  1.00 40.11  ? 102 LEU C O   1 
ATOM   7670  C CB  . LEU C 1 102 ? -14.259 -26.556 31.095  1.00 51.37  ? 102 LEU C CB  1 
ATOM   7671  C CG  . LEU C 1 102 ? -13.766 -25.110 31.001  1.00 60.65  ? 102 LEU C CG  1 
ATOM   7672  C CD1 . LEU C 1 102 ? -13.825 -24.438 32.368  1.00 65.29  ? 102 LEU C CD1 1 
ATOM   7673  C CD2 . LEU C 1 102 ? -12.351 -25.040 30.445  1.00 65.37  ? 102 LEU C CD2 1 
ATOM   7674  N N   . LYS C 1 103 ? -13.400 -27.328 28.193  1.00 45.82  ? 103 LYS C N   1 
ATOM   7675  C CA  . LYS C 1 103 ? -12.739 -27.049 26.938  1.00 46.44  ? 103 LYS C CA  1 
ATOM   7676  C C   . LYS C 1 103 ? -13.605 -27.545 25.775  1.00 42.37  ? 103 LYS C C   1 
ATOM   7677  O O   . LYS C 1 103 ? -13.674 -26.908 24.735  1.00 39.46  ? 103 LYS C O   1 
ATOM   7678  C CB  . LYS C 1 103 ? -11.347 -27.679 26.938  1.00 50.77  ? 103 LYS C CB  1 
ATOM   7679  C CG  . LYS C 1 103 ? -10.622 -27.525 25.639  1.00 56.70  ? 103 LYS C CG  1 
ATOM   7680  C CD  . LYS C 1 103 ? -9.148  -27.889 25.678  1.00 61.87  ? 103 LYS C CD  1 
ATOM   7681  C CE  . LYS C 1 103 ? -8.793  -29.126 24.876  1.00 75.86  ? 103 LYS C CE  1 
ATOM   7682  N NZ  . LYS C 1 103 ? -7.431  -29.032 24.329  1.00 77.42  ? 103 LYS C NZ  1 
ATOM   7683  N N   . ALA C 1 104 ? -14.287 -28.671 25.969  1.00 45.21  ? 104 ALA C N   1 
ATOM   7684  C CA  . ALA C 1 104 ? -15.171 -29.211 24.935  1.00 43.69  ? 104 ALA C CA  1 
ATOM   7685  C C   . ALA C 1 104 ? -16.321 -28.237 24.621  1.00 39.81  ? 104 ALA C C   1 
ATOM   7686  O O   . ALA C 1 104 ? -16.711 -28.096 23.467  1.00 42.14  ? 104 ALA C O   1 
ATOM   7687  C CB  . ALA C 1 104 ? -15.699 -30.570 25.360  1.00 49.85  ? 104 ALA C CB  1 
ATOM   7688  N N   . GLU C 1 105 ? -16.898 -27.615 25.659  1.00 39.36  ? 105 GLU C N   1 
ATOM   7689  C CA  . GLU C 1 105 ? -17.982 -26.645 25.465  1.00 40.42  ? 105 GLU C CA  1 
ATOM   7690  C C   . GLU C 1 105 ? -17.447 -25.442 24.664  1.00 37.20  ? 105 GLU C C   1 
ATOM   7691  O O   . GLU C 1 105 ? -18.137 -24.897 23.781  1.00 34.80  ? 105 GLU C O   1 
ATOM   7692  C CB  . GLU C 1 105 ? -18.581 -26.166 26.803  1.00 41.22  ? 105 GLU C CB  1 
ATOM   7693  C CG  . GLU C 1 105 ? -19.508 -27.175 27.490  1.00 40.09  ? 105 GLU C CG  1 
ATOM   7694  C CD  . GLU C 1 105 ? -20.799 -27.458 26.760  1.00 44.16  ? 105 GLU C CD  1 
ATOM   7695  O OE1 . GLU C 1 105 ? -21.185 -26.663 25.871  1.00 46.10  ? 105 GLU C OE1 1 
ATOM   7696  O OE2 . GLU C 1 105 ? -21.412 -28.505 27.056  1.00 51.19  ? 105 GLU C OE2 1 
ATOM   7697  N N   . ILE C 1 106 ? -16.222 -25.037 24.970  1.00 30.72  ? 106 ILE C N   1 
ATOM   7698  C CA  . ILE C 1 106 ? -15.630 -23.902 24.297  1.00 38.09  ? 106 ILE C CA  1 
ATOM   7699  C C   . ILE C 1 106 ? -15.473 -24.236 22.809  1.00 39.43  ? 106 ILE C C   1 
ATOM   7700  O O   . ILE C 1 106 ? -15.785 -23.424 21.953  1.00 43.33  ? 106 ILE C O   1 
ATOM   7701  C CB  . ILE C 1 106 ? -14.300 -23.515 24.959  1.00 38.81  ? 106 ILE C CB  1 
ATOM   7702  C CG1 . ILE C 1 106 ? -14.534 -22.739 26.250  1.00 38.08  ? 106 ILE C CG1 1 
ATOM   7703  C CG2 . ILE C 1 106 ? -13.416 -22.740 23.989  1.00 42.80  ? 106 ILE C CG2 1 
ATOM   7704  C CD1 . ILE C 1 106 ? -13.347 -22.739 27.202  1.00 39.23  ? 106 ILE C CD1 1 
ATOM   7705  N N   . GLU C 1 107 ? -15.004 -25.449 22.526  1.00 42.08  ? 107 GLU C N   1 
ATOM   7706  C CA  . GLU C 1 107 ? -14.767 -25.886 21.163  1.00 39.92  ? 107 GLU C CA  1 
ATOM   7707  C C   . GLU C 1 107 ? -16.073 -25.902 20.382  1.00 37.76  ? 107 GLU C C   1 
ATOM   7708  O O   . GLU C 1 107 ? -16.118 -25.404 19.245  1.00 36.96  ? 107 GLU C O   1 
ATOM   7709  C CB  . GLU C 1 107 ? -14.079 -27.244 21.139  1.00 40.40  ? 107 GLU C CB  1 
ATOM   7710  C CG  . GLU C 1 107 ? -13.891 -27.773 19.729  1.00 46.60  ? 107 GLU C CG  1 
ATOM   7711  C CD  . GLU C 1 107 ? -12.745 -28.713 19.518  1.00 47.19  ? 107 GLU C CD  1 
ATOM   7712  O OE1 . GLU C 1 107 ? -12.236 -29.299 20.490  1.00 49.72  ? 107 GLU C OE1 1 
ATOM   7713  O OE2 . GLU C 1 107 ? -12.339 -28.833 18.343  1.00 57.47  ? 107 GLU C OE2 1 
ATOM   7714  N N   . TRP C 1 108 ? -17.124 -26.489 20.988  1.00 36.41  ? 108 TRP C N   1 
ATOM   7715  C CA  . TRP C 1 108 ? -18.452 -26.526 20.379  1.00 34.55  ? 108 TRP C CA  1 
ATOM   7716  C C   . TRP C 1 108 ? -18.901 -25.124 19.966  1.00 39.69  ? 108 TRP C C   1 
ATOM   7717  O O   . TRP C 1 108 ? -19.364 -24.935 18.849  1.00 46.54  ? 108 TRP C O   1 
ATOM   7718  C CB  . TRP C 1 108 ? -19.467 -27.151 21.334  1.00 36.08  ? 108 TRP C CB  1 
ATOM   7719  C CG  . TRP C 1 108 ? -20.878 -27.132 20.796  1.00 39.46  ? 108 TRP C CG  1 
ATOM   7720  C CD1 . TRP C 1 108 ? -21.448 -28.027 19.942  1.00 40.03  ? 108 TRP C CD1 1 
ATOM   7721  C CD2 . TRP C 1 108 ? -21.879 -26.135 21.054  1.00 40.08  ? 108 TRP C CD2 1 
ATOM   7722  N NE1 . TRP C 1 108 ? -22.743 -27.670 19.674  1.00 40.55  ? 108 TRP C NE1 1 
ATOM   7723  C CE2 . TRP C 1 108 ? -23.034 -26.513 20.334  1.00 38.13  ? 108 TRP C CE2 1 
ATOM   7724  C CE3 . TRP C 1 108 ? -21.910 -24.961 21.815  1.00 44.56  ? 108 TRP C CE3 1 
ATOM   7725  C CZ2 . TRP C 1 108 ? -24.204 -25.762 20.354  1.00 39.35  ? 108 TRP C CZ2 1 
ATOM   7726  C CZ3 . TRP C 1 108 ? -23.076 -24.210 21.836  1.00 45.15  ? 108 TRP C CZ3 1 
ATOM   7727  C CH2 . TRP C 1 108 ? -24.203 -24.607 21.112  1.00 41.60  ? 108 TRP C CH2 1 
ATOM   7728  N N   . GLY C 1 109 ? -18.825 -24.158 20.911  1.00 41.59  ? 109 GLY C N   1 
ATOM   7729  C CA  . GLY C 1 109 ? -19.255 -22.775 20.658  1.00 40.86  ? 109 GLY C CA  1 
ATOM   7730  C C   . GLY C 1 109 ? -18.489 -22.132 19.492  1.00 38.51  ? 109 GLY C C   1 
ATOM   7731  O O   . GLY C 1 109 ? -19.097 -21.527 18.613  1.00 42.20  ? 109 GLY C O   1 
ATOM   7732  N N   . ALA C 1 110 ? -17.145 -22.274 19.500  1.00 33.42  ? 110 ALA C N   1 
ATOM   7733  C CA  . ALA C 1 110 ? -16.295 -21.704 18.458  1.00 32.25  ? 110 ALA C CA  1 
ATOM   7734  C C   . ALA C 1 110 ? -16.673 -22.278 17.076  1.00 35.45  ? 110 ALA C C   1 
ATOM   7735  O O   . ALA C 1 110 ? -16.777 -21.533 16.093  1.00 34.37  ? 110 ALA C O   1 
ATOM   7736  C CB  . ALA C 1 110 ? -14.842 -21.949 18.778  1.00 33.12  ? 110 ALA C CB  1 
ATOM   7737  N N   . ALA C 1 111 ? -16.922 -23.591 17.018  1.00 34.78  ? 111 ALA C N   1 
ATOM   7738  C CA  . ALA C 1 111 ? -17.268 -24.251 15.765  1.00 35.32  ? 111 ALA C CA  1 
ATOM   7739  C C   . ALA C 1 111 ? -18.621 -23.773 15.281  1.00 34.62  ? 111 ALA C C   1 
ATOM   7740  O O   . ALA C 1 111 ? -18.800 -23.565 14.105  1.00 35.13  ? 111 ALA C O   1 
ATOM   7741  C CB  . ALA C 1 111 ? -17.259 -25.769 15.934  1.00 38.62  ? 111 ALA C CB  1 
ATOM   7742  N N   . ARG C 1 112 ? -19.584 -23.648 16.205  1.00 38.62  ? 112 ARG C N   1 
ATOM   7743  C CA  . ARG C 1 112 ? -20.927 -23.154 15.868  1.00 41.58  ? 112 ARG C CA  1 
ATOM   7744  C C   . ARG C 1 112 ? -20.845 -21.725 15.294  1.00 39.13  ? 112 ARG C C   1 
ATOM   7745  O O   . ARG C 1 112 ? -21.511 -21.409 14.321  1.00 39.60  ? 112 ARG C O   1 
ATOM   7746  C CB  . ARG C 1 112 ? -21.846 -23.134 17.093  1.00 42.88  ? 112 ARG C CB  1 
ATOM   7747  C CG  . ARG C 1 112 ? -23.300 -22.794 16.782  1.00 42.62  ? 112 ARG C CG  1 
ATOM   7748  C CD  . ARG C 1 112 ? -24.030 -22.231 17.986  1.00 43.46  ? 112 ARG C CD  1 
ATOM   7749  N NE  . ARG C 1 112 ? -25.473 -22.179 17.756  1.00 43.18  ? 112 ARG C NE  1 
ATOM   7750  C CZ  . ARG C 1 112 ? -26.157 -21.117 17.313  1.00 45.81  ? 112 ARG C CZ  1 
ATOM   7751  N NH1 . ARG C 1 112 ? -25.536 -19.962 17.040  1.00 47.47  ? 112 ARG C NH1 1 
ATOM   7752  N NH2 . ARG C 1 112 ? -27.460 -21.230 17.121  1.00 40.72  ? 112 ARG C NH2 1 
ATOM   7753  N N   . ALA C 1 113 ? -20.016 -20.889 15.898  1.00 36.21  ? 113 ALA C N   1 
ATOM   7754  C CA  . ALA C 1 113 ? -19.919 -19.490 15.508  1.00 38.51  ? 113 ALA C CA  1 
ATOM   7755  C C   . ALA C 1 113 ? -19.269 -19.366 14.119  1.00 38.57  ? 113 ALA C C   1 
ATOM   7756  O O   . ALA C 1 113 ? -19.709 -18.579 13.297  1.00 36.76  ? 113 ALA C O   1 
ATOM   7757  C CB  . ALA C 1 113 ? -19.152 -18.727 16.557  1.00 35.12  ? 113 ALA C CB  1 
ATOM   7758  N N   . ILE C 1 114 ? -18.231 -20.161 13.876  1.00 40.94  ? 114 ILE C N   1 
ATOM   7759  C CA  . ILE C 1 114 ? -17.585 -20.219 12.564  1.00 43.53  ? 114 ILE C CA  1 
ATOM   7760  C C   . ILE C 1 114 ? -18.629 -20.588 11.496  1.00 37.04  ? 114 ILE C C   1 
ATOM   7761  O O   . ILE C 1 114 ? -18.676 -19.979 10.445  1.00 35.64  ? 114 ILE C O   1 
ATOM   7762  C CB  . ILE C 1 114 ? -16.403 -21.232 12.584  1.00 48.38  ? 114 ILE C CB  1 
ATOM   7763  C CG1 . ILE C 1 114 ? -15.213 -20.705 13.361  1.00 54.11  ? 114 ILE C CG1 1 
ATOM   7764  C CG2 . ILE C 1 114 ? -16.006 -21.654 11.173  1.00 48.68  ? 114 ILE C CG2 1 
ATOM   7765  C CD1 . ILE C 1 114 ? -14.837 -19.271 13.042  1.00 58.38  ? 114 ILE C CD1 1 
ATOM   7766  N N   . THR C 1 115 ? -19.437 -21.627 11.778  1.00 35.36  ? 115 THR C N   1 
ATOM   7767  C CA  . THR C 1 115 ? -20.428 -22.122 10.831  1.00 33.58  ? 115 THR C CA  1 
ATOM   7768  C C   . THR C 1 115 ? -21.424 -21.017 10.499  1.00 31.41  ? 115 THR C C   1 
ATOM   7769  O O   . THR C 1 115 ? -21.790 -20.859 9.348   1.00 32.82  ? 115 THR C O   1 
ATOM   7770  C CB  . THR C 1 115 ? -21.154 -23.343 11.389  1.00 30.53  ? 115 THR C CB  1 
ATOM   7771  O OG1 . THR C 1 115 ? -20.164 -24.296 11.738  1.00 30.57  ? 115 THR C OG1 1 
ATOM   7772  C CG2 . THR C 1 115 ? -22.090 -23.951 10.369  1.00 31.11  ? 115 THR C CG2 1 
ATOM   7773  N N   . LEU C 1 116 ? -21.890 -20.285 11.531  1.00 32.12  ? 116 LEU C N   1 
ATOM   7774  C CA  . LEU C 1 116 ? -22.922 -19.274 11.352  1.00 34.08  ? 116 LEU C CA  1 
ATOM   7775  C C   . LEU C 1 116 ? -22.359 -18.077 10.579  1.00 33.23  ? 116 LEU C C   1 
ATOM   7776  O O   . LEU C 1 116 ? -23.013 -17.571 9.673   1.00 34.06  ? 116 LEU C O   1 
ATOM   7777  C CB  . LEU C 1 116 ? -23.489 -18.847 12.693  1.00 38.38  ? 116 LEU C CB  1 
ATOM   7778  C CG  . LEU C 1 116 ? -24.521 -17.722 12.657  1.00 40.75  ? 116 LEU C CG  1 
ATOM   7779  C CD1 . LEU C 1 116 ? -25.693 -18.021 11.728  1.00 37.84  ? 116 LEU C CD1 1 
ATOM   7780  C CD2 . LEU C 1 116 ? -25.018 -17.468 14.075  1.00 52.92  ? 116 LEU C CD2 1 
ATOM   7781  N N   . GLU C 1 117 ? -21.120 -17.679 10.898  1.00 36.68  ? 117 GLU C N   1 
ATOM   7782  C CA  . GLU C 1 117 ? -20.458 -16.550 10.221  1.00 39.94  ? 117 GLU C CA  1 
ATOM   7783  C C   . GLU C 1 117 ? -20.269 -16.855 8.737   1.00 40.33  ? 117 GLU C C   1 
ATOM   7784  O O   . GLU C 1 117 ? -20.477 -15.984 7.897   1.00 37.01  ? 117 GLU C O   1 
ATOM   7785  C CB  . GLU C 1 117 ? -19.115 -16.238 10.862  1.00 43.87  ? 117 GLU C CB  1 
ATOM   7786  C CG  . GLU C 1 117 ? -19.229 -15.479 12.185  1.00 52.71  ? 117 GLU C CG  1 
ATOM   7787  C CD  . GLU C 1 117 ? -18.173 -15.864 13.242  1.00 67.92  ? 117 GLU C CD  1 
ATOM   7788  O OE1 . GLU C 1 117 ? -16.995 -16.140 12.868  1.00 73.65  ? 117 GLU C OE1 1 
ATOM   7789  O OE2 . GLU C 1 117 ? -18.512 -15.864 14.458  1.00 63.71  ? 117 GLU C OE2 1 
ATOM   7790  N N   . SER C 1 118 ? -19.911 -18.123 8.426   1.00 40.43  ? 118 SER C N   1 
ATOM   7791  C CA  . SER C 1 118 ? -19.587 -18.530 7.059   1.00 38.05  ? 118 SER C CA  1 
ATOM   7792  C C   . SER C 1 118 ? -20.813 -18.418 6.151   1.00 40.80  ? 118 SER C C   1 
ATOM   7793  O O   . SER C 1 118 ? -20.669 -18.205 4.941   1.00 36.35  ? 118 SER C O   1 
ATOM   7794  C CB  . SER C 1 118 ? -19.011 -19.929 7.029   1.00 35.54  ? 118 SER C CB  1 
ATOM   7795  O OG  . SER C 1 118 ? -17.827 -19.998 7.807   1.00 31.46  ? 118 SER C OG  1 
ATOM   7796  N N   . ALA C 1 119 ? -22.027 -18.529 6.740   1.00 41.27  ? 119 ALA C N   1 
ATOM   7797  C CA  . ALA C 1 119 ? -23.263 -18.491 5.950   1.00 39.29  ? 119 ALA C CA  1 
ATOM   7798  C C   . ALA C 1 119 ? -23.434 -17.140 5.257   1.00 38.34  ? 119 ALA C C   1 
ATOM   7799  O O   . ALA C 1 119 ? -24.097 -17.076 4.241   1.00 45.24  ? 119 ALA C O   1 
ATOM   7800  C CB  . ALA C 1 119 ? -24.460 -18.804 6.806   1.00 40.40  ? 119 ALA C CB  1 
ATOM   7801  N N   . SER C 1 120 ? -22.827 -16.071 5.813   1.00 36.23  ? 120 SER C N   1 
ATOM   7802  C CA  . SER C 1 120 ? -22.915 -14.728 5.230   1.00 39.84  ? 120 SER C CA  1 
ATOM   7803  C C   . SER C 1 120 ? -21.878 -14.505 4.119   1.00 38.67  ? 120 SER C C   1 
ATOM   7804  O O   . SER C 1 120 ? -21.948 -13.499 3.425   1.00 46.65  ? 120 SER C O   1 
ATOM   7805  C CB  . SER C 1 120 ? -22.786 -13.659 6.292   1.00 39.05  ? 120 SER C CB  1 
ATOM   7806  O OG  . SER C 1 120 ? -21.709 -13.943 7.160   1.00 51.56  ? 120 SER C OG  1 
ATOM   7807  N N   . PHE C 1 121 ? -20.919 -15.425 3.949   1.00 38.24  ? 121 PHE C N   1 
ATOM   7808  C CA  . PHE C 1 121 ? -19.753 -15.146 3.097   1.00 38.80  ? 121 PHE C CA  1 
ATOM   7809  C C   . PHE C 1 121 ? -20.136 -15.139 1.606   1.00 37.64  ? 121 PHE C C   1 
ATOM   7810  O O   . PHE C 1 121 ? -19.663 -14.287 0.866   1.00 43.44  ? 121 PHE C O   1 
ATOM   7811  C CB  . PHE C 1 121 ? -18.579 -16.097 3.359   1.00 39.02  ? 121 PHE C CB  1 
ATOM   7812  C CG  . PHE C 1 121 ? -17.882 -15.872 4.694   1.00 39.41  ? 121 PHE C CG  1 
ATOM   7813  C CD1 . PHE C 1 121 ? -18.169 -14.754 5.474   1.00 41.43  ? 121 PHE C CD1 1 
ATOM   7814  C CD2 . PHE C 1 121 ? -16.937 -16.774 5.167   1.00 38.91  ? 121 PHE C CD2 1 
ATOM   7815  C CE1 . PHE C 1 121 ? -17.523 -14.552 6.685   1.00 40.23  ? 121 PHE C CE1 1 
ATOM   7816  C CE2 . PHE C 1 121 ? -16.298 -16.565 6.375   1.00 40.07  ? 121 PHE C CE2 1 
ATOM   7817  C CZ  . PHE C 1 121 ? -16.606 -15.466 7.139   1.00 41.68  ? 121 PHE C CZ  1 
ATOM   7818  N N   . PRO C 1 122 ? -20.944 -16.089 1.096   1.00 39.97  ? 122 PRO C N   1 
ATOM   7819  C CA  . PRO C 1 122 ? -21.167 -16.202 -0.371  1.00 38.29  ? 122 PRO C CA  1 
ATOM   7820  C C   . PRO C 1 122 ? -21.637 -14.922 -1.093  1.00 39.89  ? 122 PRO C C   1 
ATOM   7821  O O   . PRO C 1 122 ? -21.219 -14.641 -2.213  1.00 41.18  ? 122 PRO C O   1 
ATOM   7822  C CB  . PRO C 1 122 ? -22.200 -17.317 -0.466  1.00 36.56  ? 122 PRO C CB  1 
ATOM   7823  C CG  . PRO C 1 122 ? -21.916 -18.177 0.758   1.00 41.63  ? 122 PRO C CG  1 
ATOM   7824  C CD  . PRO C 1 122 ? -21.593 -17.157 1.856   1.00 43.83  ? 122 PRO C CD  1 
ATOM   7825  N N   . ALA C 1 123 ? -22.479 -14.135 -0.449  1.00 39.38  ? 123 ALA C N   1 
ATOM   7826  C CA  . ALA C 1 123 ? -23.059 -12.977 -1.126  1.00 42.61  ? 123 ALA C CA  1 
ATOM   7827  C C   . ALA C 1 123 ? -22.040 -11.838 -1.237  1.00 40.86  ? 123 ALA C C   1 
ATOM   7828  O O   . ALA C 1 123 ? -22.212 -10.954 -2.049  1.00 51.93  ? 123 ALA C O   1 
ATOM   7829  C CB  . ALA C 1 123 ? -24.323 -12.525 -0.420  1.00 44.23  ? 123 ALA C CB  1 
ATOM   7830  N N   . ARG C 1 124 ? -20.952 -11.905 -0.460  1.00 43.13  ? 124 ARG C N   1 
ATOM   7831  C CA  . ARG C 1 124 ? -19.979 -10.806 -0.373  1.00 42.94  ? 124 ARG C CA  1 
ATOM   7832  C C   . ARG C 1 124 ? -18.878 -10.911 -1.450  1.00 42.66  ? 124 ARG C C   1 
ATOM   7833  O O   . ARG C 1 124 ? -18.062 -9.999  -1.581  1.00 49.29  ? 124 ARG C O   1 
ATOM   7834  C CB  . ARG C 1 124 ? -19.348 -10.772 1.024   1.00 47.29  ? 124 ARG C CB  1 
ATOM   7835  C CG  . ARG C 1 124 ? -20.322 -10.297 2.097   1.00 53.27  ? 124 ARG C CG  1 
ATOM   7836  C CD  . ARG C 1 124 ? -19.792 -10.496 3.489   1.00 55.70  ? 124 ARG C CD  1 
ATOM   7837  N NE  . ARG C 1 124 ? -18.704 -9.561  3.802   1.00 56.63  ? 124 ARG C NE  1 
ATOM   7838  C CZ  . ARG C 1 124 ? -17.856 -9.716  4.826   1.00 61.19  ? 124 ARG C CZ  1 
ATOM   7839  N NH1 . ARG C 1 124 ? -18.054 -10.688 5.729   1.00 60.78  ? 124 ARG C NH1 1 
ATOM   7840  N NH2 . ARG C 1 124 ? -16.818 -8.910  4.942   1.00 58.26  ? 124 ARG C NH2 1 
ATOM   7841  N N   . VAL C 1 125 ? -18.843 -12.020 -2.200  1.00 40.91  ? 125 VAL C N   1 
ATOM   7842  C CA  . VAL C 1 125 ? -17.805 -12.230 -3.206  1.00 41.70  ? 125 VAL C CA  1 
ATOM   7843  C C   . VAL C 1 125 ? -18.017 -11.260 -4.379  1.00 43.79  ? 125 VAL C C   1 
ATOM   7844  O O   . VAL C 1 125 ? -19.118 -11.119 -4.884  1.00 46.42  ? 125 VAL C O   1 
ATOM   7845  C CB  . VAL C 1 125 ? -17.770 -13.683 -3.693  1.00 39.46  ? 125 VAL C CB  1 
ATOM   7846  C CG1 . VAL C 1 125 ? -16.829 -13.863 -4.872  1.00 42.25  ? 125 VAL C CG1 1 
ATOM   7847  C CG2 . VAL C 1 125 ? -17.393 -14.629 -2.574  1.00 40.54  ? 125 VAL C CG2 1 
ATOM   7848  N N   . HIS C 1 126 ? -16.928 -10.618 -4.800  1.00 43.71  ? 126 HIS C N   1 
ATOM   7849  C CA  . HIS C 1 126 ? -16.965 -9.556  -5.788  1.00 46.92  ? 126 HIS C CA  1 
ATOM   7850  C C   . HIS C 1 126 ? -15.840 -9.764  -6.797  1.00 43.48  ? 126 HIS C C   1 
ATOM   7851  O O   . HIS C 1 126 ? -14.681 -9.923  -6.404  1.00 39.37  ? 126 HIS C O   1 
ATOM   7852  C CB  . HIS C 1 126 ? -16.694 -8.185  -5.140  1.00 51.10  ? 126 HIS C CB  1 
ATOM   7853  C CG  . HIS C 1 126 ? -17.774 -7.653  -4.286  1.00 56.85  ? 126 HIS C CG  1 
ATOM   7854  N ND1 . HIS C 1 126 ? -17.587 -6.529  -3.499  1.00 72.14  ? 126 HIS C ND1 1 
ATOM   7855  C CD2 . HIS C 1 126 ? -19.069 -7.997  -4.144  1.00 63.69  ? 126 HIS C CD2 1 
ATOM   7856  C CE1 . HIS C 1 126 ? -18.732 -6.222  -2.883  1.00 71.30  ? 126 HIS C CE1 1 
ATOM   7857  N NE2 . HIS C 1 126 ? -19.647 -7.101  -3.259  1.00 64.46  ? 126 HIS C NE2 1 
ATOM   7858  N N   . GLY C 1 127 ? -16.187 -9.715  -8.095  1.00 42.02  ? 127 GLY C N   1 
ATOM   7859  C CA  . GLY C 1 127 ? -15.227 -9.438  -9.171  1.00 35.73  ? 127 GLY C CA  1 
ATOM   7860  C C   . GLY C 1 127 ? -15.076 -7.930  -9.404  1.00 33.16  ? 127 GLY C C   1 
ATOM   7861  O O   . GLY C 1 127 ? -15.617 -7.149  -8.669  1.00 32.67  ? 127 GLY C O   1 
ATOM   7862  N N   . ARG C 1 128 ? -14.384 -7.553  -10.480 1.00 41.47  ? 128 ARG C N   1 
ATOM   7863  C CA  . ARG C 1 128 ? -13.890 -6.185  -10.665 1.00 47.94  ? 128 ARG C CA  1 
ATOM   7864  C C   . ARG C 1 128 ? -13.986 -5.782  -12.155 1.00 43.80  ? 128 ARG C C   1 
ATOM   7865  O O   . ARG C 1 128 ? -13.827 -6.622  -13.040 1.00 40.76  ? 128 ARG C O   1 
ATOM   7866  C CB  . ARG C 1 128 ? -12.448 -6.214  -10.142 1.00 58.80  ? 128 ARG C CB  1 
ATOM   7867  C CG  . ARG C 1 128 ? -11.824 -4.875  -9.801  1.00 74.16  ? 128 ARG C CG  1 
ATOM   7868  C CD  . ARG C 1 128 ? -10.787 -4.994  -8.645  1.00 85.57  ? 128 ARG C CD  1 
ATOM   7869  N NE  . ARG C 1 128 ? -9.401  -5.245  -9.078  1.00 103.28 ? 128 ARG C NE  1 
ATOM   7870  C CZ  . ARG C 1 128 ? -8.550  -6.145  -8.522  1.00 110.47 ? 128 ARG C CZ  1 
ATOM   7871  N NH1 . ARG C 1 128 ? -8.999  -7.074  -7.707  1.00 111.90 ? 128 ARG C NH1 1 
ATOM   7872  N NH2 . ARG C 1 128 ? -7.258  -6.111  -8.805  1.00 105.03 ? 128 ARG C NH2 1 
ATOM   7873  N N   . ILE C 1 129 ? -14.221 -4.478  -12.423 1.00 46.97  ? 129 ILE C N   1 
ATOM   7874  C CA  . ILE C 1 129 ? -14.201 -3.946  -13.801 1.00 45.35  ? 129 ILE C CA  1 
ATOM   7875  C C   . ILE C 1 129 ? -13.236 -2.781  -13.864 1.00 43.49  ? 129 ILE C C   1 
ATOM   7876  O O   . ILE C 1 129 ? -13.345 -1.853  -13.085 1.00 48.77  ? 129 ILE C O   1 
ATOM   7877  C CB  . ILE C 1 129 ? -15.597 -3.520  -14.291 1.00 45.13  ? 129 ILE C CB  1 
ATOM   7878  C CG1 . ILE C 1 129 ? -16.602 -4.618  -14.121 1.00 46.34  ? 129 ILE C CG1 1 
ATOM   7879  C CG2 . ILE C 1 129 ? -15.530 -3.042  -15.746 1.00 48.46  ? 129 ILE C CG2 1 
ATOM   7880  C CD1 . ILE C 1 129 ? -17.982 -4.284  -14.628 1.00 44.02  ? 129 ILE C CD1 1 
ATOM   7881  N N   . VAL C 1 130 ? -12.282 -2.862  -14.795 1.00 49.28  ? 130 VAL C N   1 
ATOM   7882  C CA  . VAL C 1 130 ? -11.133 -1.979  -14.800 1.00 51.51  ? 130 VAL C CA  1 
ATOM   7883  C C   . VAL C 1 130 ? -11.033 -1.297  -16.166 1.00 54.78  ? 130 VAL C C   1 
ATOM   7884  O O   . VAL C 1 130 ? -11.303 -1.905  -17.218 1.00 52.87  ? 130 VAL C O   1 
ATOM   7885  C CB  . VAL C 1 130 ? -9.822  -2.710  -14.433 1.00 55.57  ? 130 VAL C CB  1 
ATOM   7886  C CG1 . VAL C 1 130 ? -8.586  -1.861  -14.735 1.00 57.35  ? 130 VAL C CG1 1 
ATOM   7887  C CG2 . VAL C 1 130 ? -9.806  -3.169  -12.976 1.00 51.78  ? 130 VAL C CG2 1 
ATOM   7888  N N   . GLU C 1 131 ? -10.583 -0.043  -16.112 1.00 63.43  ? 131 GLU C N   1 
ATOM   7889  C CA  . GLU C 1 131 ? -10.496 0.862   -17.250 1.00 70.69  ? 131 GLU C CA  1 
ATOM   7890  C C   . GLU C 1 131 ? -9.164  0.576   -18.004 1.00 66.29  ? 131 GLU C C   1 
ATOM   7891  O O   . GLU C 1 131 ? -8.224  0.048   -17.417 1.00 59.35  ? 131 GLU C O   1 
ATOM   7892  C CB  . GLU C 1 131 ? -10.614 2.265   -16.591 1.00 84.51  ? 131 GLU C CB  1 
ATOM   7893  C CG  . GLU C 1 131 ? -11.397 3.317   -17.389 1.00 93.30  ? 131 GLU C CG  1 
ATOM   7894  C CD  . GLU C 1 131 ? -12.860 2.996   -17.670 1.00 97.28  ? 131 GLU C CD  1 
ATOM   7895  O OE1 . GLU C 1 131 ? -13.396 2.051   -17.063 1.00 100.19 ? 131 GLU C OE1 1 
ATOM   7896  O OE2 . GLU C 1 131 ? -13.455 3.690   -18.518 1.00 103.46 ? 131 GLU C OE2 1 
ATOM   7897  N N   . SER C 1 132 ? -9.106  0.909   -19.312 1.00 68.69  ? 132 SER C N   1 
ATOM   7898  C CA  . SER C 1 132 ? -7.918  0.653   -20.134 1.00 56.53  ? 132 SER C CA  1 
ATOM   7899  C C   . SER C 1 132 ? -7.513  1.916   -20.889 1.00 52.72  ? 132 SER C C   1 
ATOM   7900  O O   . SER C 1 132 ? -8.369  2.677   -21.324 1.00 54.90  ? 132 SER C O   1 
ATOM   7901  C CB  . SER C 1 132 ? -8.170  -0.475  -21.087 1.00 59.34  ? 132 SER C CB  1 
ATOM   7902  O OG  . SER C 1 132 ? -7.141  -0.570  -22.066 1.00 55.80  ? 132 SER C OG  1 
ATOM   7903  N N   . ASP C 1 133 ? -6.192  2.101   -21.088 1.00 55.71  ? 133 ASP C N   1 
ATOM   7904  C CA  . ASP C 1 133 ? -5.688  3.182   -21.936 1.00 54.78  ? 133 ASP C CA  1 
ATOM   7905  C C   . ASP C 1 133 ? -5.943  2.872   -23.414 1.00 56.85  ? 133 ASP C C   1 
ATOM   7906  O O   . ASP C 1 133 ? -6.096  3.787   -24.222 1.00 60.16  ? 133 ASP C O   1 
ATOM   7907  C CB  . ASP C 1 133 ? -4.227  3.469   -21.679 1.00 52.84  ? 133 ASP C CB  1 
ATOM   7908  C CG  . ASP C 1 133 ? -3.944  4.252   -20.408 1.00 59.28  ? 133 ASP C CG  1 
ATOM   7909  O OD1 . ASP C 1 133 ? -4.747  5.183   -20.088 1.00 57.32  ? 133 ASP C OD1 1 
ATOM   7910  O OD2 . ASP C 1 133 ? -2.919  3.954   -19.762 1.00 52.70  ? 133 ASP C OD2 1 
ATOM   7911  N N   . VAL C 1 134 ? -5.958  1.591   -23.763 1.00 54.19  ? 134 VAL C N   1 
ATOM   7912  C CA  . VAL C 1 134 ? -6.230  1.187   -25.121 1.00 55.96  ? 134 VAL C CA  1 
ATOM   7913  C C   . VAL C 1 134 ? -7.681  1.535   -25.455 1.00 60.76  ? 134 VAL C C   1 
ATOM   7914  O O   . VAL C 1 134 ? -8.587  1.185   -24.709 1.00 59.33  ? 134 VAL C O   1 
ATOM   7915  C CB  . VAL C 1 134 ? -5.960  -0.309  -25.314 1.00 58.53  ? 134 VAL C CB  1 
ATOM   7916  C CG1 . VAL C 1 134 ? -6.463  -0.796  -26.670 1.00 57.65  ? 134 VAL C CG1 1 
ATOM   7917  C CG2 . VAL C 1 134 ? -4.483  -0.649  -25.118 1.00 56.36  ? 134 VAL C CG2 1 
ATOM   7918  N N   . PRO C 1 135 ? -7.950  2.213   -26.596 1.00 72.40  ? 135 PRO C N   1 
ATOM   7919  C CA  . PRO C 1 135 ? -9.327  2.533   -26.988 1.00 70.73  ? 135 PRO C CA  1 
ATOM   7920  C C   . PRO C 1 135 ? -10.151 1.272   -27.251 1.00 67.08  ? 135 PRO C C   1 
ATOM   7921  O O   . PRO C 1 135 ? -9.704  0.383   -27.973 1.00 59.67  ? 135 PRO C O   1 
ATOM   7922  C CB  . PRO C 1 135 ? -9.161  3.395   -28.269 1.00 66.52  ? 135 PRO C CB  1 
ATOM   7923  C CG  . PRO C 1 135 ? -7.696  3.834   -28.244 1.00 71.75  ? 135 PRO C CG  1 
ATOM   7924  C CD  . PRO C 1 135 ? -6.951  2.720   -27.547 1.00 72.31  ? 135 PRO C CD  1 
ATOM   7925  N N   . GLY C 1 136 ? -11.357 1.212   -26.648 1.00 61.10  ? 136 GLY C N   1 
ATOM   7926  C CA  . GLY C 1 136 ? -12.314 0.136   -26.906 1.00 62.05  ? 136 GLY C CA  1 
ATOM   7927  C C   . GLY C 1 136 ? -12.009 -1.144  -26.100 1.00 59.75  ? 136 GLY C C   1 
ATOM   7928  O O   . GLY C 1 136 ? -12.575 -2.187  -26.372 1.00 59.38  ? 136 GLY C O   1 
ATOM   7929  N N   . LYS C 1 137 ? -11.112 -1.046  -25.106 1.00 58.14  ? 137 LYS C N   1 
ATOM   7930  C CA  . LYS C 1 137 ? -10.691 -2.209  -24.344 1.00 55.93  ? 137 LYS C CA  1 
ATOM   7931  C C   . LYS C 1 137 ? -11.235 -2.112  -22.920 1.00 56.01  ? 137 LYS C C   1 
ATOM   7932  O O   . LYS C 1 137 ? -11.129 -1.065  -22.284 1.00 49.59  ? 137 LYS C O   1 
ATOM   7933  C CB  . LYS C 1 137 ? -9.169  -2.355  -24.308 1.00 62.19  ? 137 LYS C CB  1 
ATOM   7934  C CG  . LYS C 1 137 ? -8.708  -3.570  -23.533 1.00 65.96  ? 137 LYS C CG  1 
ATOM   7935  C CD  . LYS C 1 137 ? -7.466  -4.246  -24.082 1.00 75.90  ? 137 LYS C CD  1 
ATOM   7936  C CE  . LYS C 1 137 ? -6.313  -4.218  -23.136 1.00 81.79  ? 137 LYS C CE  1 
ATOM   7937  N NZ  . LYS C 1 137 ? -5.484  -5.418  -23.290 1.00 90.89  ? 137 LYS C NZ  1 
ATOM   7938  N N   . GLU C 1 138 ? -11.796 -3.235  -22.434 1.00 53.13  ? 138 GLU C N   1 
ATOM   7939  C CA  . GLU C 1 138 ? -12.327 -3.339  -21.082 1.00 55.99  ? 138 GLU C CA  1 
ATOM   7940  C C   . GLU C 1 138 ? -11.711 -4.573  -20.401 1.00 53.84  ? 138 GLU C C   1 
ATOM   7941  O O   . GLU C 1 138 ? -11.617 -5.636  -21.008 1.00 50.70  ? 138 GLU C O   1 
ATOM   7942  C CB  . GLU C 1 138 ? -13.860 -3.392  -21.173 1.00 61.39  ? 138 GLU C CB  1 
ATOM   7943  C CG  . GLU C 1 138 ? -14.533 -4.302  -20.156 1.00 64.48  ? 138 GLU C CG  1 
ATOM   7944  C CD  . GLU C 1 138 ? -16.005 -4.549  -20.460 1.00 69.81  ? 138 GLU C CD  1 
ATOM   7945  O OE1 . GLU C 1 138 ? -16.279 -5.158  -21.511 1.00 70.13  ? 138 GLU C OE1 1 
ATOM   7946  O OE2 . GLU C 1 138 ? -16.874 -4.121  -19.669 1.00 72.80  ? 138 GLU C OE2 1 
ATOM   7947  N N   . SER C 1 139 ? -11.309 -4.405  -19.129 1.00 44.90  ? 139 SER C N   1 
ATOM   7948  C CA  . SER C 1 139 ? -10.865 -5.505  -18.292 1.00 49.13  ? 139 SER C CA  1 
ATOM   7949  C C   . SER C 1 139 ? -11.969 -5.909  -17.314 1.00 45.96  ? 139 SER C C   1 
ATOM   7950  O O   . SER C 1 139 ? -12.474 -5.084  -16.557 1.00 37.36  ? 139 SER C O   1 
ATOM   7951  C CB  . SER C 1 139 ? -9.603  -5.155  -17.556 1.00 58.01  ? 139 SER C CB  1 
ATOM   7952  O OG  . SER C 1 139 ? -8.461  -5.639  -18.240 1.00 64.64  ? 139 SER C OG  1 
ATOM   7953  N N   . ARG C 1 140 ? -12.303 -7.201  -17.331 1.00 48.20  ? 140 ARG C N   1 
ATOM   7954  C CA  . ARG C 1 140 ? -13.256 -7.790  -16.399 1.00 49.44  ? 140 ARG C CA  1 
ATOM   7955  C C   . ARG C 1 140 ? -12.549 -8.876  -15.608 1.00 47.12  ? 140 ARG C C   1 
ATOM   7956  O O   . ARG C 1 140 ? -11.926 -9.743  -16.194 1.00 53.71  ? 140 ARG C O   1 
ATOM   7957  C CB  . ARG C 1 140 ? -14.456 -8.360  -17.171 1.00 49.16  ? 140 ARG C CB  1 
ATOM   7958  C CG  . ARG C 1 140 ? -15.758 -7.631  -16.913 1.00 57.04  ? 140 ARG C CG  1 
ATOM   7959  C CD  . ARG C 1 140 ? -16.893 -8.227  -17.687 1.00 60.10  ? 140 ARG C CD  1 
ATOM   7960  N NE  . ARG C 1 140 ? -16.917 -7.746  -19.065 1.00 59.57  ? 140 ARG C NE  1 
ATOM   7961  C CZ  . ARG C 1 140 ? -17.406 -8.413  -20.082 1.00 55.48  ? 140 ARG C CZ  1 
ATOM   7962  N NH1 . ARG C 1 140 ? -17.798 -9.664  -19.934 1.00 56.06  ? 140 ARG C NH1 1 
ATOM   7963  N NH2 . ARG C 1 140 ? -17.416 -7.867  -21.269 1.00 60.72  ? 140 ARG C NH2 1 
ATOM   7964  N N   . VAL C 1 141 ? -12.631 -8.801  -14.267 1.00 49.85  ? 141 VAL C N   1 
ATOM   7965  C CA  . VAL C 1 141 ? -11.986 -9.778  -13.385 1.00 43.84  ? 141 VAL C CA  1 
ATOM   7966  C C   . VAL C 1 141 ? -13.064 -10.592 -12.699 1.00 42.58  ? 141 VAL C C   1 
ATOM   7967  O O   . VAL C 1 141 ? -13.887 -10.039 -12.012 1.00 45.50  ? 141 VAL C O   1 
ATOM   7968  C CB  . VAL C 1 141 ? -11.092 -9.081  -12.352 1.00 48.25  ? 141 VAL C CB  1 
ATOM   7969  C CG1 . VAL C 1 141 ? -10.219 -10.071 -11.577 1.00 42.39  ? 141 VAL C CG1 1 
ATOM   7970  C CG2 . VAL C 1 141 ? -10.229 -8.007  -12.998 1.00 56.17  ? 141 VAL C CG2 1 
ATOM   7971  N N   . TYR C 1 142 ? -13.032 -11.910 -12.890 1.00 38.97  ? 142 TYR C N   1 
ATOM   7972  C CA  . TYR C 1 142 ? -14.013 -12.814 -12.301 1.00 39.89  ? 142 TYR C CA  1 
ATOM   7973  C C   . TYR C 1 142 ? -13.384 -13.547 -11.100 1.00 42.42  ? 142 TYR C C   1 
ATOM   7974  O O   . TYR C 1 142 ? -12.278 -14.075 -11.194 1.00 41.52  ? 142 TYR C O   1 
ATOM   7975  C CB  . TYR C 1 142 ? -14.505 -13.795 -13.381 1.00 40.35  ? 142 TYR C CB  1 
ATOM   7976  C CG  . TYR C 1 142 ? -15.313 -13.142 -14.495 1.00 44.02  ? 142 TYR C CG  1 
ATOM   7977  C CD1 . TYR C 1 142 ? -16.653 -12.834 -14.316 1.00 47.39  ? 142 TYR C CD1 1 
ATOM   7978  C CD2 . TYR C 1 142 ? -14.733 -12.813 -15.716 1.00 49.16  ? 142 TYR C CD2 1 
ATOM   7979  C CE1 . TYR C 1 142 ? -17.388 -12.194 -15.304 1.00 45.32  ? 142 TYR C CE1 1 
ATOM   7980  C CE2 . TYR C 1 142 ? -15.455 -12.173 -16.714 1.00 49.47  ? 142 TYR C CE2 1 
ATOM   7981  C CZ  . TYR C 1 142 ? -16.785 -11.861 -16.507 1.00 47.57  ? 142 TYR C CZ  1 
ATOM   7982  O OH  . TYR C 1 142 ? -17.484 -11.258 -17.505 1.00 41.29  ? 142 TYR C OH  1 
ATOM   7983  N N   . ARG C 1 143 ? -14.133 -13.623 -9.997  1.00 41.21  ? 143 ARG C N   1 
ATOM   7984  C CA  . ARG C 1 143 ? -13.656 -14.254 -8.770  1.00 43.10  ? 143 ARG C CA  1 
ATOM   7985  C C   . ARG C 1 143 ? -14.411 -15.562 -8.562  1.00 39.32  ? 143 ARG C C   1 
ATOM   7986  O O   . ARG C 1 143 ? -15.606 -15.547 -8.462  1.00 46.04  ? 143 ARG C O   1 
ATOM   7987  C CB  . ARG C 1 143 ? -13.873 -13.304 -7.581  1.00 42.90  ? 143 ARG C CB  1 
ATOM   7988  C CG  . ARG C 1 143 ? -13.063 -13.680 -6.365  1.00 48.05  ? 143 ARG C CG  1 
ATOM   7989  C CD  . ARG C 1 143 ? -12.390 -12.487 -5.739  1.00 52.86  ? 143 ARG C CD  1 
ATOM   7990  N NE  . ARG C 1 143 ? -11.488 -12.960 -4.691  1.00 70.99  ? 143 ARG C NE  1 
ATOM   7991  C CZ  . ARG C 1 143 ? -10.164 -12.810 -4.673  1.00 78.10  ? 143 ARG C CZ  1 
ATOM   7992  N NH1 . ARG C 1 143 ? -9.584  -11.916 -5.457  1.00 76.84  ? 143 ARG C NH1 1 
ATOM   7993  N NH2 . ARG C 1 143 ? -9.434  -13.499 -3.797  1.00 75.46  ? 143 ARG C NH2 1 
ATOM   7994  N N   . SER C 1 144 ? -13.686 -16.693 -8.491  1.00 41.31  ? 144 SER C N   1 
ATOM   7995  C CA  . SER C 1 144 ? -14.314 -18.030 -8.454  1.00 40.05  ? 144 SER C CA  1 
ATOM   7996  C C   . SER C 1 144 ? -13.689 -18.901 -7.355  1.00 42.68  ? 144 SER C C   1 
ATOM   7997  O O   . SER C 1 144 ? -12.575 -18.638 -6.892  1.00 47.12  ? 144 SER C O   1 
ATOM   7998  C CB  . SER C 1 144 ? -14.200 -18.714 -9.783  1.00 40.31  ? 144 SER C CB  1 
ATOM   7999  O OG  . SER C 1 144 ? -14.277 -17.778 -10.850 1.00 53.23  ? 144 SER C OG  1 
ATOM   8000  N N   . ALA C 1 145 ? -14.369 -20.001 -7.029  1.00 42.09  ? 145 ALA C N   1 
ATOM   8001  C CA  . ALA C 1 145 ? -13.824 -21.013 -6.122  1.00 41.12  ? 145 ALA C CA  1 
ATOM   8002  C C   . ALA C 1 145 ? -12.566 -21.623 -6.723  1.00 41.21  ? 145 ALA C C   1 
ATOM   8003  O O   . ALA C 1 145 ? -12.444 -21.727 -7.934  1.00 52.09  ? 145 ALA C O   1 
ATOM   8004  C CB  . ALA C 1 145 ? -14.865 -22.078 -5.823  1.00 37.65  ? 145 ALA C CB  1 
ATOM   8005  N N   . ILE C 1 146 ? -11.633 -22.020 -5.856  1.00 38.93  ? 146 ILE C N   1 
ATOM   8006  C CA  . ILE C 1 146 ? -10.387 -22.619 -6.296  1.00 39.57  ? 146 ILE C CA  1 
ATOM   8007  C C   . ILE C 1 146 ? -10.674 -23.971 -6.943  1.00 37.09  ? 146 ILE C C   1 
ATOM   8008  O O   . ILE C 1 146 ? -10.061 -24.315 -7.927  1.00 41.44  ? 146 ILE C O   1 
ATOM   8009  C CB  . ILE C 1 146 ? -9.393  -22.742 -5.132  1.00 45.05  ? 146 ILE C CB  1 
ATOM   8010  C CG1 . ILE C 1 146 ? -8.949  -21.382 -4.646  1.00 51.09  ? 146 ILE C CG1 1 
ATOM   8011  C CG2 . ILE C 1 146 ? -8.198  -23.610 -5.524  1.00 43.56  ? 146 ILE C CG2 1 
ATOM   8012  C CD1 . ILE C 1 146 ? -8.436  -21.371 -3.221  1.00 57.85  ? 146 ILE C CD1 1 
ATOM   8013  N N   . GLY C 1 147 ? -11.630 -24.713 -6.397  1.00 36.56  ? 147 GLY C N   1 
ATOM   8014  C CA  . GLY C 1 147 ? -11.901 -26.072 -6.866  1.00 37.82  ? 147 GLY C CA  1 
ATOM   8015  C C   . GLY C 1 147 ? -11.988 -27.052 -5.698  1.00 36.31  ? 147 GLY C C   1 
ATOM   8016  O O   . GLY C 1 147 ? -13.007 -27.117 -5.008  1.00 34.76  ? 147 GLY C O   1 
ATOM   8017  N N   . VAL C 1 148 ? -10.904 -27.790 -5.466  1.00 37.82  ? 148 VAL C N   1 
ATOM   8018  C CA  . VAL C 1 148 ? -10.859 -28.740 -4.366  1.00 39.86  ? 148 VAL C CA  1 
ATOM   8019  C C   . VAL C 1 148 ? -9.794  -28.303 -3.362  1.00 35.88  ? 148 VAL C C   1 
ATOM   8020  O O   . VAL C 1 148 ? -8.669  -27.984 -3.739  1.00 38.07  ? 148 VAL C O   1 
ATOM   8021  C CB  . VAL C 1 148 ? -10.608 -30.168 -4.852  1.00 38.80  ? 148 VAL C CB  1 
ATOM   8022  C CG1 . VAL C 1 148 ? -10.657 -31.156 -3.694  1.00 42.34  ? 148 VAL C CG1 1 
ATOM   8023  C CG2 . VAL C 1 148 ? -11.591 -30.572 -5.949  1.00 40.34  ? 148 VAL C CG2 1 
ATOM   8024  N N   . VAL C 1 149 ? -10.163 -28.320 -2.080  1.00 33.65  ? 149 VAL C N   1 
ATOM   8025  C CA  . VAL C 1 149 ? -9.247  -27.974 -1.007  1.00 33.21  ? 149 VAL C CA  1 
ATOM   8026  C C   . VAL C 1 149 ? -8.976  -29.227 -0.182  1.00 33.62  ? 149 VAL C C   1 
ATOM   8027  O O   . VAL C 1 149 ? -9.906  -29.902 0.232   1.00 33.04  ? 149 VAL C O   1 
ATOM   8028  C CB  . VAL C 1 149 ? -9.818  -26.849 -0.131  1.00 34.88  ? 149 VAL C CB  1 
ATOM   8029  C CG1 . VAL C 1 149 ? -8.810  -26.355 0.878   1.00 37.72  ? 149 VAL C CG1 1 
ATOM   8030  C CG2 . VAL C 1 149 ? -10.337 -25.695 -0.961  1.00 36.25  ? 149 VAL C CG2 1 
ATOM   8031  N N   . GLY C 1 150 ? -7.688  -29.532 0.023   1.00 35.99  ? 150 GLY C N   1 
ATOM   8032  C CA  . GLY C 1 150 ? -7.276  -30.611 0.893   1.00 37.59  ? 150 GLY C CA  1 
ATOM   8033  C C   . GLY C 1 150 ? -6.961  -30.072 2.279   1.00 38.45  ? 150 GLY C C   1 
ATOM   8034  O O   . GLY C 1 150 ? -6.149  -29.177 2.415   1.00 41.04  ? 150 GLY C O   1 
ATOM   8035  N N   . VAL C 1 151 ? -7.637  -30.620 3.302   1.00 39.86  ? 151 VAL C N   1 
ATOM   8036  C CA  . VAL C 1 151 ? -7.562  -30.091 4.654   1.00 37.68  ? 151 VAL C CA  1 
ATOM   8037  C C   . VAL C 1 151 ? -6.960  -31.151 5.561   1.00 38.43  ? 151 VAL C C   1 
ATOM   8038  O O   . VAL C 1 151 ? -7.516  -32.230 5.704   1.00 38.42  ? 151 VAL C O   1 
ATOM   8039  C CB  . VAL C 1 151 ? -8.959  -29.665 5.132   1.00 38.24  ? 151 VAL C CB  1 
ATOM   8040  C CG1 . VAL C 1 151 ? -8.955  -29.201 6.583   1.00 41.84  ? 151 VAL C CG1 1 
ATOM   8041  C CG2 . VAL C 1 151 ? -9.562  -28.597 4.235   1.00 35.61  ? 151 VAL C CG2 1 
ATOM   8042  N N   . ILE C 1 152 ? -5.801  -30.840 6.155   1.00 40.48  ? 152 ILE C N   1 
ATOM   8043  C CA  . ILE C 1 152 ? -5.195  -31.710 7.156   1.00 38.63  ? 152 ILE C CA  1 
ATOM   8044  C C   . ILE C 1 152 ? -5.514  -31.144 8.535   1.00 39.58  ? 152 ILE C C   1 
ATOM   8045  O O   . ILE C 1 152 ? -5.225  -29.976 8.809   1.00 45.88  ? 152 ILE C O   1 
ATOM   8046  C CB  . ILE C 1 152 ? -3.683  -31.832 6.917   1.00 39.27  ? 152 ILE C CB  1 
ATOM   8047  C CG1 . ILE C 1 152 ? -3.394  -32.400 5.558   1.00 37.37  ? 152 ILE C CG1 1 
ATOM   8048  C CG2 . ILE C 1 152 ? -3.009  -32.655 8.025   1.00 43.30  ? 152 ILE C CG2 1 
ATOM   8049  C CD1 . ILE C 1 152 ? -2.073  -31.963 4.997   1.00 40.75  ? 152 ILE C CD1 1 
ATOM   8050  N N   . SER C 1 153 ? -6.129  -31.967 9.390   1.00 36.61  ? 153 SER C N   1 
ATOM   8051  C CA  . SER C 1 153 ? -6.661  -31.487 10.653  1.00 40.59  ? 153 SER C CA  1 
ATOM   8052  C C   . SER C 1 153 ? -5.797  -32.004 11.802  1.00 38.01  ? 153 SER C C   1 
ATOM   8053  O O   . SER C 1 153 ? -5.358  -33.137 11.775  1.00 40.25  ? 153 SER C O   1 
ATOM   8054  C CB  . SER C 1 153 ? -8.139  -31.880 10.818  1.00 42.98  ? 153 SER C CB  1 
ATOM   8055  O OG  . SER C 1 153 ? -8.276  -33.181 11.352  1.00 54.61  ? 153 SER C OG  1 
ATOM   8056  N N   . PRO C 1 154 ? -5.566  -31.196 12.864  1.00 41.94  ? 154 PRO C N   1 
ATOM   8057  C CA  . PRO C 1 154 ? -4.742  -31.625 14.014  1.00 41.16  ? 154 PRO C CA  1 
ATOM   8058  C C   . PRO C 1 154 ? -5.506  -32.390 15.101  1.00 46.83  ? 154 PRO C C   1 
ATOM   8059  O O   . PRO C 1 154 ? -6.751  -32.462 15.075  1.00 44.64  ? 154 PRO C O   1 
ATOM   8060  C CB  . PRO C 1 154 ? -4.280  -30.278 14.509  1.00 43.51  ? 154 PRO C CB  1 
ATOM   8061  C CG  . PRO C 1 154 ? -5.533  -29.395 14.374  1.00 42.83  ? 154 PRO C CG  1 
ATOM   8062  C CD  . PRO C 1 154 ? -6.167  -29.863 13.064  1.00 43.34  ? 154 PRO C CD  1 
ATOM   8063  N N   . TRP C 1 155 ? -4.771  -32.888 16.113  1.00 52.91  ? 155 TRP C N   1 
ATOM   8064  C CA  . TRP C 1 155 ? -5.411  -33.640 17.198  1.00 57.72  ? 155 TRP C CA  1 
ATOM   8065  C C   . TRP C 1 155 ? -5.828  -32.718 18.361  1.00 56.40  ? 155 TRP C C   1 
ATOM   8066  O O   . TRP C 1 155 ? -6.661  -33.106 19.171  1.00 53.75  ? 155 TRP C O   1 
ATOM   8067  C CB  . TRP C 1 155 ? -4.518  -34.780 17.696  1.00 55.66  ? 155 TRP C CB  1 
ATOM   8068  C CG  . TRP C 1 155 ? -3.104  -34.380 17.984  1.00 61.66  ? 155 TRP C CG  1 
ATOM   8069  C CD1 . TRP C 1 155 ? -2.020  -34.596 17.192  1.00 59.95  ? 155 TRP C CD1 1 
ATOM   8070  C CD2 . TRP C 1 155 ? -2.612  -33.711 19.171  1.00 69.60  ? 155 TRP C CD2 1 
ATOM   8071  N NE1 . TRP C 1 155 ? -0.889  -34.108 17.793  1.00 70.69  ? 155 TRP C NE1 1 
ATOM   8072  C CE2 . TRP C 1 155 ? -1.217  -33.561 19.008  1.00 67.28  ? 155 TRP C CE2 1 
ATOM   8073  C CE3 . TRP C 1 155 ? -3.210  -33.233 20.348  1.00 67.99  ? 155 TRP C CE3 1 
ATOM   8074  C CZ2 . TRP C 1 155 ? -0.418  -32.943 19.966  1.00 66.09  ? 155 TRP C CZ2 1 
ATOM   8075  C CZ3 . TRP C 1 155 ? -2.418  -32.628 21.299  1.00 65.29  ? 155 TRP C CZ3 1 
ATOM   8076  C CH2 . TRP C 1 155 ? -1.036  -32.498 21.113  1.00 68.27  ? 155 TRP C CH2 1 
ATOM   8077  N N   . ASN C 1 156 ? -5.256  -31.505 18.431  1.00 57.44  ? 156 ASN C N   1 
ATOM   8078  C CA  . ASN C 1 156 ? -5.464  -30.629 19.590  1.00 68.09  ? 156 ASN C CA  1 
ATOM   8079  C C   . ASN C 1 156 ? -6.932  -30.170 19.656  1.00 67.61  ? 156 ASN C C   1 
ATOM   8080  O O   . ASN C 1 156 ? -7.646  -30.511 20.595  1.00 87.21  ? 156 ASN C O   1 
ATOM   8081  C CB  . ASN C 1 156 ? -4.504  -29.442 19.593  1.00 84.81  ? 156 ASN C CB  1 
ATOM   8082  C CG  . ASN C 1 156 ? -4.463  -28.748 20.941  1.00 89.53  ? 156 ASN C CG  1 
ATOM   8083  O OD1 . ASN C 1 156 ? -5.316  -27.904 21.241  1.00 81.13  ? 156 ASN C OD1 1 
ATOM   8084  N ND2 . ASN C 1 156 ? -3.473  -29.076 21.758  1.00 101.09 ? 156 ASN C ND2 1 
ATOM   8085  N N   . PHE C 1 157 ? -7.366  -29.382 18.673  1.00 53.71  ? 157 PHE C N   1 
ATOM   8086  C CA  . PHE C 1 157 ? -8.759  -28.933 18.613  1.00 57.53  ? 157 PHE C CA  1 
ATOM   8087  C C   . PHE C 1 157 ? -9.374  -29.408 17.314  1.00 51.97  ? 157 PHE C C   1 
ATOM   8088  O O   . PHE C 1 157 ? -9.596  -28.613 16.405  1.00 48.40  ? 157 PHE C O   1 
ATOM   8089  C CB  . PHE C 1 157 ? -8.868  -27.408 18.696  1.00 65.72  ? 157 PHE C CB  1 
ATOM   8090  C CG  . PHE C 1 157 ? -9.233  -26.885 20.063  1.00 65.57  ? 157 PHE C CG  1 
ATOM   8091  C CD1 . PHE C 1 157 ? -8.355  -27.004 21.121  1.00 78.06  ? 157 PHE C CD1 1 
ATOM   8092  C CD2 . PHE C 1 157 ? -10.457 -26.278 20.285  1.00 68.87  ? 157 PHE C CD2 1 
ATOM   8093  C CE1 . PHE C 1 157 ? -8.702  -26.537 22.370  1.00 77.55  ? 157 PHE C CE1 1 
ATOM   8094  C CE2 . PHE C 1 157 ? -10.795 -25.808 21.535  1.00 65.79  ? 157 PHE C CE2 1 
ATOM   8095  C CZ  . PHE C 1 157 ? -9.926  -25.938 22.570  1.00 72.57  ? 157 PHE C CZ  1 
ATOM   8096  N N   . PRO C 1 158 ? -9.593  -30.722 17.151  1.00 47.64  ? 158 PRO C N   1 
ATOM   8097  C CA  . PRO C 1 158 ? -9.826  -31.287 15.832  1.00 48.49  ? 158 PRO C CA  1 
ATOM   8098  C C   . PRO C 1 158 ? -11.087 -30.710 15.176  1.00 45.16  ? 158 PRO C C   1 
ATOM   8099  O O   . PRO C 1 158 ? -11.041 -30.264 14.033  1.00 47.65  ? 158 PRO C O   1 
ATOM   8100  C CB  . PRO C 1 158 ? -9.915  -32.813 16.095  1.00 49.47  ? 158 PRO C CB  1 
ATOM   8101  C CG  . PRO C 1 158 ? -10.251 -32.917 17.575  1.00 49.03  ? 158 PRO C CG  1 
ATOM   8102  C CD  . PRO C 1 158 ? -9.603  -31.718 18.216  1.00 48.83  ? 158 PRO C CD  1 
ATOM   8103  N N   . LEU C 1 159 ? -12.187 -30.662 15.931  1.00 38.44  ? 159 LEU C N   1 
ATOM   8104  C CA  . LEU C 1 159 ? -13.473 -30.262 15.370  1.00 43.42  ? 159 LEU C CA  1 
ATOM   8105  C C   . LEU C 1 159 ? -13.425 -28.791 14.938  1.00 38.08  ? 159 LEU C C   1 
ATOM   8106  O O   . LEU C 1 159 ? -13.760 -28.469 13.822  1.00 35.69  ? 159 LEU C O   1 
ATOM   8107  C CB  . LEU C 1 159 ? -14.620 -30.494 16.347  1.00 43.14  ? 159 LEU C CB  1 
ATOM   8108  C CG  . LEU C 1 159 ? -16.029 -30.324 15.752  1.00 42.71  ? 159 LEU C CG  1 
ATOM   8109  C CD1 . LEU C 1 159 ? -16.697 -31.660 15.516  1.00 44.62  ? 159 LEU C CD1 1 
ATOM   8110  C CD2 . LEU C 1 159 ? -16.892 -29.466 16.629  1.00 46.90  ? 159 LEU C CD2 1 
ATOM   8111  N N   . HIS C 1 160 ? -13.060 -27.911 15.854  1.00 35.63  ? 160 HIS C N   1 
ATOM   8112  C CA  . HIS C 1 160 ? -13.104 -26.498 15.576  1.00 39.91  ? 160 HIS C CA  1 
ATOM   8113  C C   . HIS C 1 160 ? -12.170 -26.166 14.415  1.00 43.12  ? 160 HIS C C   1 
ATOM   8114  O O   . HIS C 1 160 ? -12.542 -25.421 13.518  1.00 43.29  ? 160 HIS C O   1 
ATOM   8115  C CB  . HIS C 1 160 ? -12.750 -25.675 16.812  1.00 43.74  ? 160 HIS C CB  1 
ATOM   8116  C CG  . HIS C 1 160 ? -12.508 -24.217 16.494  1.00 51.20  ? 160 HIS C CG  1 
ATOM   8117  N ND1 . HIS C 1 160 ? -11.433 -23.527 16.993  1.00 49.39  ? 160 HIS C ND1 1 
ATOM   8118  C CD2 . HIS C 1 160 ? -13.181 -23.328 15.707  1.00 50.86  ? 160 HIS C CD2 1 
ATOM   8119  C CE1 . HIS C 1 160 ? -11.449 -22.282 16.529  1.00 49.08  ? 160 HIS C CE1 1 
ATOM   8120  N NE2 . HIS C 1 160 ? -12.490 -22.147 15.738  1.00 49.69  ? 160 HIS C NE2 1 
ATOM   8121  N N   . LEU C 1 161 ? -10.940 -26.694 14.463  1.00 46.12  ? 161 LEU C N   1 
ATOM   8122  C CA  . LEU C 1 161 ? -9.915  -26.321 13.504  1.00 42.84  ? 161 LEU C CA  1 
ATOM   8123  C C   . LEU C 1 161 ? -10.206 -26.920 12.121  1.00 46.70  ? 161 LEU C C   1 
ATOM   8124  O O   . LEU C 1 161 ? -9.879  -26.301 11.103  1.00 50.29  ? 161 LEU C O   1 
ATOM   8125  C CB  . LEU C 1 161 ? -8.562  -26.724 14.034  1.00 43.75  ? 161 LEU C CB  1 
ATOM   8126  C CG  . LEU C 1 161 ? -8.075  -25.897 15.217  1.00 50.91  ? 161 LEU C CG  1 
ATOM   8127  C CD1 . LEU C 1 161 ? -6.640  -26.198 15.542  1.00 52.23  ? 161 LEU C CD1 1 
ATOM   8128  C CD2 . LEU C 1 161 ? -8.270  -24.409 14.923  1.00 50.45  ? 161 LEU C CD2 1 
ATOM   8129  N N   . THR C 1 162 ? -10.869 -28.084 12.078  1.00 38.50  ? 162 THR C N   1 
ATOM   8130  C CA  . THR C 1 162 ? -11.326 -28.627 10.805  1.00 40.18  ? 162 THR C CA  1 
ATOM   8131  C C   . THR C 1 162 ? -12.383 -27.679 10.210  1.00 38.46  ? 162 THR C C   1 
ATOM   8132  O O   . THR C 1 162 ? -12.326 -27.345 9.024   1.00 28.43  ? 162 THR C O   1 
ATOM   8133  C CB  . THR C 1 162 ? -11.883 -30.042 10.978  1.00 42.29  ? 162 THR C CB  1 
ATOM   8134  O OG1 . THR C 1 162 ? -10.883 -30.795 11.640  1.00 42.89  ? 162 THR C OG1 1 
ATOM   8135  C CG2 . THR C 1 162 ? -12.198 -30.710 9.655   1.00 41.62  ? 162 THR C CG2 1 
ATOM   8136  N N   . GLN C 1 163 ? -13.364 -27.282 11.046  1.00 35.60  ? 163 GLN C N   1 
ATOM   8137  C CA  . GLN C 1 163 ? -14.495 -26.489 10.590  1.00 35.84  ? 163 GLN C CA  1 
ATOM   8138  C C   . GLN C 1 163 ? -14.008 -25.101 10.142  1.00 37.56  ? 163 GLN C C   1 
ATOM   8139  O O   . GLN C 1 163 ? -14.597 -24.481 9.257   1.00 34.25  ? 163 GLN C O   1 
ATOM   8140  C CB  . GLN C 1 163 ? -15.522 -26.377 11.714  1.00 37.80  ? 163 GLN C CB  1 
ATOM   8141  C CG  . GLN C 1 163 ? -16.857 -25.757 11.302  1.00 37.99  ? 163 GLN C CG  1 
ATOM   8142  C CD  . GLN C 1 163 ? -17.717 -26.700 10.500  1.00 38.57  ? 163 GLN C CD  1 
ATOM   8143  O OE1 . GLN C 1 163 ? -17.228 -27.710 9.970   1.00 38.54  ? 163 GLN C OE1 1 
ATOM   8144  N NE2 . GLN C 1 163 ? -19.011 -26.372 10.381  1.00 38.69  ? 163 GLN C NE2 1 
ATOM   8145  N N   . ARG C 1 164 ? -12.923 -24.635 10.753  1.00 38.43  ? 164 ARG C N   1 
ATOM   8146  C CA  . ARG C 1 164 ? -12.362 -23.338 10.436  1.00 37.39  ? 164 ARG C CA  1 
ATOM   8147  C C   . ARG C 1 164 ? -11.963 -23.279 8.949   1.00 39.55  ? 164 ARG C C   1 
ATOM   8148  O O   . ARG C 1 164 ? -11.992 -22.211 8.342   1.00 39.46  ? 164 ARG C O   1 
ATOM   8149  C CB  . ARG C 1 164 ? -11.183 -23.069 11.357  1.00 42.13  ? 164 ARG C CB  1 
ATOM   8150  C CG  . ARG C 1 164 ? -10.895 -21.600 11.604  1.00 44.48  ? 164 ARG C CG  1 
ATOM   8151  C CD  . ARG C 1 164 ? -9.495  -21.398 12.157  1.00 47.99  ? 164 ARG C CD  1 
ATOM   8152  N NE  . ARG C 1 164 ? -9.275  -19.998 12.514  1.00 59.86  ? 164 ARG C NE  1 
ATOM   8153  C CZ  . ARG C 1 164 ? -8.734  -19.088 11.715  1.00 67.07  ? 164 ARG C CZ  1 
ATOM   8154  N NH1 . ARG C 1 164 ? -8.120  -19.463 10.605  1.00 76.83  ? 164 ARG C NH1 1 
ATOM   8155  N NH2 . ARG C 1 164 ? -8.787  -17.803 12.043  1.00 65.71  ? 164 ARG C NH2 1 
ATOM   8156  N N   . SER C 1 165 ? -11.611 -24.431 8.357   1.00 37.99  ? 165 SER C N   1 
ATOM   8157  C CA  . SER C 1 165 ? -11.319 -24.486 6.912   1.00 43.57  ? 165 SER C CA  1 
ATOM   8158  C C   . SER C 1 165 ? -12.550 -24.938 6.108   1.00 37.66  ? 165 SER C C   1 
ATOM   8159  O O   . SER C 1 165 ? -12.827 -24.390 5.067   1.00 39.09  ? 165 SER C O   1 
ATOM   8160  C CB  . SER C 1 165 ? -10.124 -25.365 6.617   1.00 40.21  ? 165 SER C CB  1 
ATOM   8161  O OG  . SER C 1 165 ? -8.981  -24.890 7.310   1.00 43.12  ? 165 SER C OG  1 
ATOM   8162  N N   . ILE C 1 166 ? -13.268 -25.924 6.629   1.00 35.49  ? 166 ILE C N   1 
ATOM   8163  C CA  . ILE C 1 166 ? -14.317 -26.622 5.896   1.00 37.24  ? 166 ILE C CA  1 
ATOM   8164  C C   . ILE C 1 166 ? -15.479 -25.660 5.620   1.00 33.01  ? 166 ILE C C   1 
ATOM   8165  O O   . ILE C 1 166 ? -15.949 -25.560 4.488   1.00 32.55  ? 166 ILE C O   1 
ATOM   8166  C CB  . ILE C 1 166 ? -14.765 -27.897 6.686   1.00 44.07  ? 166 ILE C CB  1 
ATOM   8167  C CG1 . ILE C 1 166 ? -13.739 -28.975 6.603   1.00 47.27  ? 166 ILE C CG1 1 
ATOM   8168  C CG2 . ILE C 1 166 ? -16.110 -28.416 6.235   1.00 47.67  ? 166 ILE C CG2 1 
ATOM   8169  C CD1 . ILE C 1 166 ? -12.957 -28.960 5.317   1.00 43.88  ? 166 ILE C CD1 1 
ATOM   8170  N N   . ALA C 1 167 ? -15.952 -24.968 6.654   1.00 32.36  ? 167 ALA C N   1 
ATOM   8171  C CA  . ALA C 1 167 ? -17.188 -24.216 6.546   1.00 29.65  ? 167 ALA C CA  1 
ATOM   8172  C C   . ALA C 1 167 ? -17.043 -23.093 5.506   1.00 32.88  ? 167 ALA C C   1 
ATOM   8173  O O   . ALA C 1 167 ? -17.842 -23.036 4.561   1.00 37.09  ? 167 ALA C O   1 
ATOM   8174  C CB  . ALA C 1 167 ? -17.604 -23.711 7.872   1.00 28.72  ? 167 ALA C CB  1 
ATOM   8175  N N   . PRO C 1 168 ? -16.014 -22.199 5.580   1.00 29.39  ? 168 PRO C N   1 
ATOM   8176  C CA  . PRO C 1 168 ? -15.862 -21.155 4.561   1.00 35.19  ? 168 PRO C CA  1 
ATOM   8177  C C   . PRO C 1 168 ? -15.560 -21.699 3.156   1.00 34.87  ? 168 PRO C C   1 
ATOM   8178  O O   . PRO C 1 168 ? -16.023 -21.156 2.169   1.00 38.16  ? 168 PRO C O   1 
ATOM   8179  C CB  . PRO C 1 168 ? -14.715 -20.259 5.096   1.00 33.90  ? 168 PRO C CB  1 
ATOM   8180  C CG  . PRO C 1 168 ? -13.966 -21.151 6.031   1.00 33.42  ? 168 PRO C CG  1 
ATOM   8181  C CD  . PRO C 1 168 ? -15.020 -22.093 6.639   1.00 31.20  ? 168 PRO C CD  1 
ATOM   8182  N N   . ALA C 1 169 ? -14.761 -22.745 3.070   1.00 33.42  ? 169 ALA C N   1 
ATOM   8183  C CA  . ALA C 1 169 ? -14.390 -23.274 1.770   1.00 35.26  ? 169 ALA C CA  1 
ATOM   8184  C C   . ALA C 1 169 ? -15.634 -23.746 1.041   1.00 36.39  ? 169 ALA C C   1 
ATOM   8185  O O   . ALA C 1 169 ? -15.845 -23.404 -0.124  1.00 31.68  ? 169 ALA C O   1 
ATOM   8186  C CB  . ALA C 1 169 ? -13.399 -24.380 1.917   1.00 38.28  ? 169 ALA C CB  1 
ATOM   8187  N N   . LEU C 1 170 ? -16.457 -24.526 1.747   1.00 39.02  ? 170 LEU C N   1 
ATOM   8188  C CA  . LEU C 1 170 ? -17.689 -25.065 1.179   1.00 37.23  ? 170 LEU C CA  1 
ATOM   8189  C C   . LEU C 1 170 ? -18.649 -23.928 0.809   1.00 34.84  ? 170 LEU C C   1 
ATOM   8190  O O   . LEU C 1 170 ? -19.272 -23.961 -0.244  1.00 33.71  ? 170 LEU C O   1 
ATOM   8191  C CB  . LEU C 1 170 ? -18.334 -26.047 2.157   1.00 33.63  ? 170 LEU C CB  1 
ATOM   8192  C CG  . LEU C 1 170 ? -17.734 -27.454 2.168   1.00 32.53  ? 170 LEU C CG  1 
ATOM   8193  C CD1 . LEU C 1 170 ? -18.249 -28.231 3.349   1.00 34.58  ? 170 LEU C CD1 1 
ATOM   8194  C CD2 . LEU C 1 170 ? -18.048 -28.173 0.886   1.00 30.47  ? 170 LEU C CD2 1 
ATOM   8195  N N   . ALA C 1 171 ? -18.783 -22.944 1.695   1.00 33.88  ? 171 ALA C N   1 
ATOM   8196  C CA  . ALA C 1 171 ? -19.732 -21.868 1.488   1.00 34.78  ? 171 ALA C CA  1 
ATOM   8197  C C   . ALA C 1 171 ? -19.434 -21.169 0.167   1.00 36.34  ? 171 ALA C C   1 
ATOM   8198  O O   . ALA C 1 171 ? -20.358 -20.790 -0.557  1.00 33.10  ? 171 ALA C O   1 
ATOM   8199  C CB  . ALA C 1 171 ? -19.689 -20.885 2.657   1.00 32.38  ? 171 ALA C CB  1 
ATOM   8200  N N   . LEU C 1 172 ? -18.137 -20.982 -0.121  1.00 35.37  ? 172 LEU C N   1 
ATOM   8201  C CA  . LEU C 1 172 ? -17.694 -20.230 -1.293  1.00 34.36  ? 172 LEU C CA  1 
ATOM   8202  C C   . LEU C 1 172 ? -17.619 -21.127 -2.547  1.00 31.52  ? 172 LEU C C   1 
ATOM   8203  O O   . LEU C 1 172 ? -17.068 -20.726 -3.527  1.00 31.09  ? 172 LEU C O   1 
ATOM   8204  C CB  . LEU C 1 172 ? -16.333 -19.598 -0.976  1.00 33.60  ? 172 LEU C CB  1 
ATOM   8205  C CG  . LEU C 1 172 ? -16.317 -18.578 0.169   1.00 34.51  ? 172 LEU C CG  1 
ATOM   8206  C CD1 . LEU C 1 172 ? -14.914 -18.152 0.512   1.00 36.16  ? 172 LEU C CD1 1 
ATOM   8207  C CD2 . LEU C 1 172 ? -17.128 -17.389 -0.173  1.00 31.16  ? 172 LEU C CD2 1 
ATOM   8208  N N   . GLY C 1 173 ? -18.163 -22.352 -2.485  1.00 38.22  ? 173 GLY C N   1 
ATOM   8209  C CA  . GLY C 1 173 ? -18.366 -23.168 -3.690  1.00 40.61  ? 173 GLY C CA  1 
ATOM   8210  C C   . GLY C 1 173 ? -17.232 -24.189 -3.947  1.00 44.16  ? 173 GLY C C   1 
ATOM   8211  O O   . GLY C 1 173 ? -17.237 -24.882 -4.981  1.00 45.16  ? 173 GLY C O   1 
ATOM   8212  N N   . ASN C 1 174 ? -16.285 -24.310 -3.009  1.00 40.23  ? 174 ASN C N   1 
ATOM   8213  C CA  . ASN C 1 174 ? -15.242 -25.325 -3.125  1.00 38.55  ? 174 ASN C CA  1 
ATOM   8214  C C   . ASN C 1 174 ? -15.788 -26.687 -2.675  1.00 37.19  ? 174 ASN C C   1 
ATOM   8215  O O   . ASN C 1 174 ? -16.816 -26.760 -2.004  1.00 33.56  ? 174 ASN C O   1 
ATOM   8216  C CB  . ASN C 1 174 ? -14.003 -24.973 -2.310  1.00 40.62  ? 174 ASN C CB  1 
ATOM   8217  C CG  . ASN C 1 174 ? -13.333 -23.706 -2.778  1.00 36.26  ? 174 ASN C CG  1 
ATOM   8218  O OD1 . ASN C 1 174 ? -12.600 -23.721 -3.775  1.00 38.30  ? 174 ASN C OD1 1 
ATOM   8219  N ND2 . ASN C 1 174 ? -13.479 -22.635 -2.015  1.00 34.91  ? 174 ASN C ND2 1 
ATOM   8220  N N   . ALA C 1 175 ? -15.074 -27.754 -3.069  1.00 33.99  ? 175 ALA C N   1 
ATOM   8221  C CA  . ALA C 1 175 ? -15.182 -29.072 -2.443  1.00 33.58  ? 175 ALA C CA  1 
ATOM   8222  C C   . ALA C 1 175 ? -13.961 -29.328 -1.543  1.00 32.48  ? 175 ALA C C   1 
ATOM   8223  O O   . ALA C 1 175 ? -12.898 -28.711 -1.722  1.00 34.18  ? 175 ALA C O   1 
ATOM   8224  C CB  . ALA C 1 175 ? -15.295 -30.133 -3.518  1.00 32.21  ? 175 ALA C CB  1 
ATOM   8225  N N   . VAL C 1 176 ? -14.108 -30.269 -0.602  1.00 32.96  ? 176 VAL C N   1 
ATOM   8226  C CA  . VAL C 1 176 ? -13.092 -30.491 0.421   1.00 32.54  ? 176 VAL C CA  1 
ATOM   8227  C C   . VAL C 1 176 ? -12.855 -31.989 0.589   1.00 35.35  ? 176 VAL C C   1 
ATOM   8228  O O   . VAL C 1 176 ? -13.792 -32.805 0.484   1.00 34.06  ? 176 VAL C O   1 
ATOM   8229  C CB  . VAL C 1 176 ? -13.462 -29.842 1.769   1.00 31.21  ? 176 VAL C CB  1 
ATOM   8230  C CG1 . VAL C 1 176 ? -13.614 -28.330 1.649   1.00 29.54  ? 176 VAL C CG1 1 
ATOM   8231  C CG2 . VAL C 1 176 ? -14.706 -30.441 2.364   1.00 31.82  ? 176 VAL C CG2 1 
ATOM   8232  N N   . VAL C 1 177 ? -11.577 -32.337 0.850   1.00 36.98  ? 177 VAL C N   1 
ATOM   8233  C CA  . VAL C 1 177 ? -11.201 -33.646 1.338   1.00 36.64  ? 177 VAL C CA  1 
ATOM   8234  C C   . VAL C 1 177 ? -10.378 -33.473 2.605   1.00 33.21  ? 177 VAL C C   1 
ATOM   8235  O O   . VAL C 1 177 ? -9.409  -32.742 2.595   1.00 33.88  ? 177 VAL C O   1 
ATOM   8236  C CB  . VAL C 1 177 ? -10.408 -34.424 0.288   1.00 36.87  ? 177 VAL C CB  1 
ATOM   8237  C CG1 . VAL C 1 177 ? -9.978  -35.772 0.825   1.00 39.38  ? 177 VAL C CG1 1 
ATOM   8238  C CG2 . VAL C 1 177 ? -11.180 -34.584 -1.002  1.00 37.24  ? 177 VAL C CG2 1 
ATOM   8239  N N   . VAL C 1 178 ? -10.730 -34.226 3.663   1.00 31.26  ? 178 VAL C N   1 
ATOM   8240  C CA  . VAL C 1 178 ? -10.135 -34.030 4.972   1.00 33.14  ? 178 VAL C CA  1 
ATOM   8241  C C   . VAL C 1 178 ? -9.343  -35.277 5.363   1.00 35.72  ? 178 VAL C C   1 
ATOM   8242  O O   . VAL C 1 178 ? -9.857  -36.382 5.302   1.00 35.51  ? 178 VAL C O   1 
ATOM   8243  C CB  . VAL C 1 178 ? -11.199 -33.708 6.035   1.00 33.74  ? 178 VAL C CB  1 
ATOM   8244  C CG1 . VAL C 1 178 ? -10.607 -33.690 7.435   1.00 33.71  ? 178 VAL C CG1 1 
ATOM   8245  C CG2 . VAL C 1 178 ? -11.922 -32.398 5.748   1.00 34.74  ? 178 VAL C CG2 1 
ATOM   8246  N N   . LYS C 1 179 ? -8.105  -35.066 5.833   1.00 43.98  ? 179 LYS C N   1 
ATOM   8247  C CA  . LYS C 1 179 ? -7.302  -36.127 6.427   1.00 43.82  ? 179 LYS C CA  1 
ATOM   8248  C C   . LYS C 1 179 ? -7.082  -35.822 7.898   1.00 37.53  ? 179 LYS C C   1 
ATOM   8249  O O   . LYS C 1 179 ? -6.192  -35.057 8.247   1.00 33.30  ? 179 LYS C O   1 
ATOM   8250  C CB  . LYS C 1 179 ? -5.952  -36.283 5.722   1.00 46.69  ? 179 LYS C CB  1 
ATOM   8251  C CG  . LYS C 1 179 ? -5.240  -37.616 6.042   1.00 51.87  ? 179 LYS C CG  1 
ATOM   8252  C CD  . LYS C 1 179 ? -3.836  -37.753 5.461   1.00 57.44  ? 179 LYS C CD  1 
ATOM   8253  C CE  . LYS C 1 179 ? -2.884  -36.727 6.003   1.00 57.37  ? 179 LYS C CE  1 
ATOM   8254  N NZ  . LYS C 1 179 ? -1.698  -37.352 6.566   1.00 60.74  ? 179 LYS C NZ  1 
ATOM   8255  N N   . PRO C 1 180 ? -7.886  -36.409 8.805   1.00 38.73  ? 180 PRO C N   1 
ATOM   8256  C CA  . PRO C 1 180 ? -7.759  -36.129 10.230  1.00 39.78  ? 180 PRO C CA  1 
ATOM   8257  C C   . PRO C 1 180 ? -6.593  -36.856 10.886  1.00 39.72  ? 180 PRO C C   1 
ATOM   8258  O O   . PRO C 1 180 ? -5.985  -37.752 10.300  1.00 43.01  ? 180 PRO C O   1 
ATOM   8259  C CB  . PRO C 1 180 ? -9.115  -36.590 10.780  1.00 38.88  ? 180 PRO C CB  1 
ATOM   8260  C CG  . PRO C 1 180 ? -9.489  -37.730 9.880   1.00 40.90  ? 180 PRO C CG  1 
ATOM   8261  C CD  . PRO C 1 180 ? -8.971  -37.345 8.505   1.00 38.64  ? 180 PRO C CD  1 
ATOM   8262  N N   . ALA C 1 181 ? -6.300  -36.470 12.108  1.00 38.89  ? 181 ALA C N   1 
ATOM   8263  C CA  . ALA C 1 181 ? -5.291  -37.150 12.897  1.00 39.81  ? 181 ALA C CA  1 
ATOM   8264  C C   . ALA C 1 181 ? -5.800  -38.539 13.279  1.00 39.46  ? 181 ALA C C   1 
ATOM   8265  O O   . ALA C 1 181 ? -6.998  -38.734 13.509  1.00 34.69  ? 181 ALA C O   1 
ATOM   8266  C CB  . ALA C 1 181 ? -4.940  -36.321 14.126  1.00 39.13  ? 181 ALA C CB  1 
ATOM   8267  N N   . SER C 1 182 ? -4.883  -39.498 13.324  1.00 41.47  ? 182 SER C N   1 
ATOM   8268  C CA  . SER C 1 182 ? -5.236  -40.895 13.541  1.00 47.54  ? 182 SER C CA  1 
ATOM   8269  C C   . SER C 1 182 ? -5.867  -41.084 14.926  1.00 40.62  ? 182 SER C C   1 
ATOM   8270  O O   . SER C 1 182 ? -6.678  -41.966 15.104  1.00 40.15  ? 182 SER C O   1 
ATOM   8271  C CB  . SER C 1 182 ? -4.024  -41.798 13.364  1.00 50.64  ? 182 SER C CB  1 
ATOM   8272  O OG  . SER C 1 182 ? -2.963  -41.382 14.215  1.00 51.24  ? 182 SER C OG  1 
ATOM   8273  N N   . ASP C 1 183 ? -5.484  -40.252 15.896  1.00 40.00  ? 183 ASP C N   1 
ATOM   8274  C CA  . ASP C 1 183 ? -6.037  -40.347 17.246  1.00 45.28  ? 183 ASP C CA  1 
ATOM   8275  C C   . ASP C 1 183 ? -7.475  -39.793 17.309  1.00 45.94  ? 183 ASP C C   1 
ATOM   8276  O O   . ASP C 1 183 ? -8.246  -40.196 18.178  1.00 45.10  ? 183 ASP C O   1 
ATOM   8277  C CB  . ASP C 1 183 ? -5.145  -39.660 18.263  1.00 53.34  ? 183 ASP C CB  1 
ATOM   8278  C CG  . ASP C 1 183 ? -3.715  -40.168 18.312  1.00 57.18  ? 183 ASP C CG  1 
ATOM   8279  O OD1 . ASP C 1 183 ? -3.517  -41.288 18.784  1.00 60.46  ? 183 ASP C OD1 1 
ATOM   8280  O OD2 . ASP C 1 183 ? -2.824  -39.451 17.829  1.00 71.87  ? 183 ASP C OD2 1 
ATOM   8281  N N   . THR C 1 184 ? -7.832  -38.846 16.413  1.00 43.43  ? 184 THR C N   1 
ATOM   8282  C CA  . THR C 1 184 ? -9.148  -38.178 16.508  1.00 43.27  ? 184 THR C CA  1 
ATOM   8283  C C   . THR C 1 184 ? -9.842  -38.137 15.144  1.00 39.92  ? 184 THR C C   1 
ATOM   8284  O O   . THR C 1 184 ? -10.160 -37.071 14.660  1.00 43.01  ? 184 THR C O   1 
ATOM   8285  C CB  . THR C 1 184 ? -8.986  -36.768 17.086  1.00 41.62  ? 184 THR C CB  1 
ATOM   8286  O OG1 . THR C 1 184 ? -8.005  -36.076 16.314  1.00 38.79  ? 184 THR C OG1 1 
ATOM   8287  C CG2 . THR C 1 184 ? -8.533  -36.786 18.534  1.00 43.32  ? 184 THR C CG2 1 
ATOM   8288  N N   . PRO C 1 185 ? -10.162 -39.291 14.527  1.00 37.67  ? 185 PRO C N   1 
ATOM   8289  C CA  . PRO C 1 185 ? -10.829 -39.301 13.230  1.00 40.93  ? 185 PRO C CA  1 
ATOM   8290  C C   . PRO C 1 185 ? -12.281 -38.837 13.270  1.00 38.94  ? 185 PRO C C   1 
ATOM   8291  O O   . PRO C 1 185 ? -12.754 -38.239 12.325  1.00 46.33  ? 185 PRO C O   1 
ATOM   8292  C CB  . PRO C 1 185 ? -10.702 -40.797 12.782  1.00 43.99  ? 185 PRO C CB  1 
ATOM   8293  C CG  . PRO C 1 185 ? -10.625 -41.566 14.079  1.00 42.29  ? 185 PRO C CG  1 
ATOM   8294  C CD  . PRO C 1 185 ? -9.826  -40.640 15.004  1.00 44.89  ? 185 PRO C CD  1 
ATOM   8295  N N   . VAL C 1 186 ? -12.968 -39.111 14.368  1.00 34.45  ? 186 VAL C N   1 
ATOM   8296  C CA  . VAL C 1 186 ? -14.377 -38.777 14.489  1.00 36.95  ? 186 VAL C CA  1 
ATOM   8297  C C   . VAL C 1 186 ? -14.530 -37.250 14.565  1.00 37.02  ? 186 VAL C C   1 
ATOM   8298  O O   . VAL C 1 186 ? -15.250 -36.661 13.771  1.00 38.87  ? 186 VAL C O   1 
ATOM   8299  C CB  . VAL C 1 186 ? -15.034 -39.461 15.701  1.00 39.91  ? 186 VAL C CB  1 
ATOM   8300  C CG1 . VAL C 1 186 ? -16.479 -39.027 15.885  1.00 42.25  ? 186 VAL C CG1 1 
ATOM   8301  C CG2 . VAL C 1 186 ? -14.952 -40.976 15.609  1.00 40.96  ? 186 VAL C CG2 1 
ATOM   8302  N N   . CYS C 1 187 ? -13.951 -36.666 15.624  1.00 36.42  ? 187 CYS C N   1 
ATOM   8303  C CA  . CYS C 1 187 ? -14.051 -35.199 15.863  1.00 42.14  ? 187 CYS C CA  1 
ATOM   8304  C C   . CYS C 1 187 ? -13.278 -34.489 14.757  1.00 45.72  ? 187 CYS C C   1 
ATOM   8305  O O   . CYS C 1 187 ? -13.181 -33.258 14.792  1.00 46.25  ? 187 CYS C O   1 
ATOM   8306  C CB  . CYS C 1 187 ? -13.513 -34.829 17.238  1.00 43.30  ? 187 CYS C CB  1 
ATOM   8307  S SG  . CYS C 1 187 ? -14.307 -35.744 18.582  1.00 51.29  ? 187 CYS C SG  1 
ATOM   8308  N N   . GLY C 1 188 ? -12.786 -35.258 13.797  1.00 42.31  ? 188 GLY C N   1 
ATOM   8309  C CA  . GLY C 1 188 ? -12.144 -34.661 12.619  1.00 37.76  ? 188 GLY C CA  1 
ATOM   8310  C C   . GLY C 1 188 ? -13.242 -34.637 11.584  1.00 33.65  ? 188 GLY C C   1 
ATOM   8311  O O   . GLY C 1 188 ? -14.356 -34.180 11.918  1.00 36.48  ? 188 GLY C O   1 
ATOM   8312  N N   . GLY C 1 189 ? -12.974 -35.109 10.382  1.00 34.21  ? 189 GLY C N   1 
ATOM   8313  C CA  . GLY C 1 189 ? -13.975 -35.043 9.307   1.00 33.24  ? 189 GLY C CA  1 
ATOM   8314  C C   . GLY C 1 189 ? -15.252 -35.822 9.559   1.00 33.27  ? 189 GLY C C   1 
ATOM   8315  O O   . GLY C 1 189 ? -16.313 -35.296 9.184   1.00 35.33  ? 189 GLY C O   1 
ATOM   8316  N N   . LEU C 1 190 ? -15.200 -37.005 10.178  1.00 31.43  ? 190 LEU C N   1 
ATOM   8317  C CA  . LEU C 1 190 ? -16.393 -37.898 10.219  1.00 33.43  ? 190 LEU C CA  1 
ATOM   8318  C C   . LEU C 1 190 ? -17.629 -37.304 10.923  1.00 32.72  ? 190 LEU C C   1 
ATOM   8319  O O   . LEU C 1 190 ? -18.724 -37.467 10.353  1.00 32.47  ? 190 LEU C O   1 
ATOM   8320  C CB  . LEU C 1 190 ? -15.971 -39.199 10.900  1.00 33.37  ? 190 LEU C CB  1 
ATOM   8321  C CG  . LEU C 1 190 ? -14.848 -39.990 10.225  1.00 32.23  ? 190 LEU C CG  1 
ATOM   8322  C CD1 . LEU C 1 190 ? -14.426 -41.142 11.117  1.00 32.60  ? 190 LEU C CD1 1 
ATOM   8323  C CD2 . LEU C 1 190 ? -15.293 -40.506 8.873   1.00 30.01  ? 190 LEU C CD2 1 
ATOM   8324  N N   . LEU C 1 191 ? -17.498 -36.623 12.058  1.00 28.52  ? 191 LEU C N   1 
ATOM   8325  C CA  . LEU C 1 191 ? -18.733 -36.113 12.706  1.00 33.35  ? 191 LEU C CA  1 
ATOM   8326  C C   . LEU C 1 191 ? -19.245 -34.928 11.881  1.00 33.10  ? 191 LEU C C   1 
ATOM   8327  O O   . LEU C 1 191 ? -20.473 -34.779 11.746  1.00 36.54  ? 191 LEU C O   1 
ATOM   8328  C CB  . LEU C 1 191 ? -18.457 -35.714 14.154  1.00 35.56  ? 191 LEU C CB  1 
ATOM   8329  C CG  . LEU C 1 191 ? -19.686 -35.444 15.026  1.00 35.93  ? 191 LEU C CG  1 
ATOM   8330  C CD1 . LEU C 1 191 ? -20.484 -36.719 15.227  1.00 36.01  ? 191 LEU C CD1 1 
ATOM   8331  C CD2 . LEU C 1 191 ? -19.262 -34.861 16.362  1.00 37.02  ? 191 LEU C CD2 1 
ATOM   8332  N N   . LEU C 1 192 ? -18.325 -34.142 11.330  1.00 34.46  ? 192 LEU C N   1 
ATOM   8333  C CA  . LEU C 1 192 ? -18.683 -32.969 10.554  1.00 32.97  ? 192 LEU C CA  1 
ATOM   8334  C C   . LEU C 1 192 ? -19.330 -33.401 9.238   1.00 33.75  ? 192 LEU C C   1 
ATOM   8335  O O   . LEU C 1 192 ? -20.271 -32.758 8.764   1.00 30.71  ? 192 LEU C O   1 
ATOM   8336  C CB  . LEU C 1 192 ? -17.449 -32.101 10.339  1.00 33.63  ? 192 LEU C CB  1 
ATOM   8337  C CG  . LEU C 1 192 ? -16.945 -31.358 11.583  1.00 36.24  ? 192 LEU C CG  1 
ATOM   8338  C CD1 . LEU C 1 192 ? -15.591 -30.671 11.345  1.00 37.42  ? 192 LEU C CD1 1 
ATOM   8339  C CD2 . LEU C 1 192 ? -17.983 -30.346 12.052  1.00 35.16  ? 192 LEU C CD2 1 
ATOM   8340  N N   . ALA C 1 193 ? -18.857 -34.520 8.662   1.00 32.95  ? 193 ALA C N   1 
ATOM   8341  C CA  . ALA C 1 193 ? -19.436 -34.991 7.398   1.00 33.26  ? 193 ALA C CA  1 
ATOM   8342  C C   . ALA C 1 193 ? -20.887 -35.429 7.618   1.00 33.48  ? 193 ALA C C   1 
ATOM   8343  O O   . ALA C 1 193 ? -21.728 -35.201 6.762   1.00 33.68  ? 193 ALA C O   1 
ATOM   8344  C CB  . ALA C 1 193 ? -18.604 -36.090 6.802   1.00 32.73  ? 193 ALA C CB  1 
ATOM   8345  N N   . ARG C 1 194 ? -21.157 -36.073 8.775   1.00 39.37  ? 194 ARG C N   1 
ATOM   8346  C CA  . ARG C 1 194 ? -22.514 -36.465 9.160   1.00 41.68  ? 194 ARG C CA  1 
ATOM   8347  C C   . ARG C 1 194 ? -23.399 -35.228 9.296   1.00 41.56  ? 194 ARG C C   1 
ATOM   8348  O O   . ARG C 1 194 ? -24.540 -35.218 8.811   1.00 39.94  ? 194 ARG C O   1 
ATOM   8349  C CB  . ARG C 1 194 ? -22.500 -37.257 10.469  1.00 50.00  ? 194 ARG C CB  1 
ATOM   8350  C CG  . ARG C 1 194 ? -21.837 -38.620 10.362  1.00 50.00  ? 194 ARG C CG  1 
ATOM   8351  C CD  . ARG C 1 194 ? -22.792 -39.748 10.006  1.00 50.00  ? 194 ARG C CD  1 
ATOM   8352  N NE  . ARG C 1 194 ? -22.124 -41.046 9.983   1.00 50.00  ? 194 ARG C NE  1 
ATOM   8353  C CZ  . ARG C 1 194 ? -22.748 -42.203 9.814   1.00 50.00  ? 194 ARG C CZ  1 
ATOM   8354  N NH1 . ARG C 1 194 ? -24.064 -42.231 9.648   1.00 50.00  ? 194 ARG C NH1 1 
ATOM   8355  N NH2 . ARG C 1 194 ? -22.058 -43.336 9.808   1.00 50.00  ? 194 ARG C NH2 1 
ATOM   8356  N N   . ILE C 1 195 ? -22.865 -34.195 9.962   1.00 38.92  ? 195 ILE C N   1 
ATOM   8357  C CA  . ILE C 1 195 ? -23.605 -32.955 10.199  1.00 39.59  ? 195 ILE C CA  1 
ATOM   8358  C C   . ILE C 1 195 ? -23.949 -32.280 8.859   1.00 36.43  ? 195 ILE C C   1 
ATOM   8359  O O   . ILE C 1 195 ? -25.078 -31.834 8.661   1.00 37.71  ? 195 ILE C O   1 
ATOM   8360  C CB  . ILE C 1 195 ? -22.812 -32.021 11.126  1.00 38.11  ? 195 ILE C CB  1 
ATOM   8361  C CG1 . ILE C 1 195 ? -22.832 -32.543 12.585  1.00 38.34  ? 195 ILE C CG1 1 
ATOM   8362  C CG2 . ILE C 1 195 ? -23.336 -30.590 11.021  1.00 38.94  ? 195 ILE C CG2 1 
ATOM   8363  C CD1 . ILE C 1 195 ? -21.800 -31.916 13.487  1.00 39.31  ? 195 ILE C CD1 1 
ATOM   8364  N N   . PHE C 1 196 ? -22.982 -32.229 7.943   1.00 31.42  ? 196 PHE C N   1 
ATOM   8365  C CA  . PHE C 1 196 ? -23.190 -31.540 6.682   1.00 33.41  ? 196 PHE C CA  1 
ATOM   8366  C C   . PHE C 1 196 ? -24.166 -32.335 5.807   1.00 36.58  ? 196 PHE C C   1 
ATOM   8367  O O   . PHE C 1 196 ? -24.923 -31.755 5.058   1.00 37.90  ? 196 PHE C O   1 
ATOM   8368  C CB  . PHE C 1 196 ? -21.858 -31.265 5.979   1.00 30.56  ? 196 PHE C CB  1 
ATOM   8369  C CG  . PHE C 1 196 ? -21.242 -29.916 6.325   1.00 29.29  ? 196 PHE C CG  1 
ATOM   8370  C CD1 . PHE C 1 196 ? -21.788 -28.737 5.832   1.00 28.44  ? 196 PHE C CD1 1 
ATOM   8371  C CD2 . PHE C 1 196 ? -20.104 -29.829 7.126   1.00 32.38  ? 196 PHE C CD2 1 
ATOM   8372  C CE1 . PHE C 1 196 ? -21.226 -27.497 6.145   1.00 27.72  ? 196 PHE C CE1 1 
ATOM   8373  C CE2 . PHE C 1 196 ? -19.543 -28.590 7.429   1.00 33.48  ? 196 PHE C CE2 1 
ATOM   8374  C CZ  . PHE C 1 196 ? -20.113 -27.426 6.939   1.00 30.54  ? 196 PHE C CZ  1 
ATOM   8375  N N   . GLU C 1 197 ? -24.129 -33.669 5.896   1.00 44.43  ? 197 GLU C N   1 
ATOM   8376  C CA  . GLU C 1 197 ? -25.043 -34.504 5.113   1.00 44.80  ? 197 GLU C CA  1 
ATOM   8377  C C   . GLU C 1 197 ? -26.479 -34.279 5.586   1.00 44.52  ? 197 GLU C C   1 
ATOM   8378  O O   . GLU C 1 197 ? -27.387 -34.125 4.763   1.00 38.77  ? 197 GLU C O   1 
ATOM   8379  C CB  . GLU C 1 197 ? -24.725 -35.992 5.197   1.00 47.31  ? 197 GLU C CB  1 
ATOM   8380  C CG  . GLU C 1 197 ? -25.744 -36.852 4.448   1.00 53.14  ? 197 GLU C CG  1 
ATOM   8381  C CD  . GLU C 1 197 ? -25.641 -38.350 4.692   1.00 64.59  ? 197 GLU C CD  1 
ATOM   8382  O OE1 . GLU C 1 197 ? -25.212 -38.777 5.796   1.00 67.11  ? 197 GLU C OE1 1 
ATOM   8383  O OE2 . GLU C 1 197 ? -25.956 -39.097 3.744   1.00 79.63  ? 197 GLU C OE2 1 
ATOM   8384  N N   . GLU C 1 198 ? -26.674 -34.278 6.917   1.00 41.48  ? 198 GLU C N   1 
ATOM   8385  C CA  . GLU C 1 198 ? -27.974 -33.992 7.505   1.00 41.48  ? 198 GLU C CA  1 
ATOM   8386  C C   . GLU C 1 198 ? -28.460 -32.606 7.046   1.00 44.63  ? 198 GLU C C   1 
ATOM   8387  O O   . GLU C 1 198 ? -29.654 -32.419 6.840   1.00 44.17  ? 198 GLU C O   1 
ATOM   8388  C CB  . GLU C 1 198 ? -27.930 -34.087 9.039   1.00 44.03  ? 198 GLU C CB  1 
ATOM   8389  C CG  . GLU C 1 198 ? -29.307 -33.932 9.715   1.00 45.31  ? 198 GLU C CG  1 
ATOM   8390  C CD  . GLU C 1 198 ? -29.283 -34.130 11.241  1.00 47.35  ? 198 GLU C CD  1 
ATOM   8391  O OE1 . GLU C 1 198 ? -28.212 -34.535 11.772  1.00 46.09  ? 198 GLU C OE1 1 
ATOM   8392  O OE2 . GLU C 1 198 ? -30.308 -33.848 11.906  1.00 48.60  ? 198 GLU C OE2 1 
ATOM   8393  N N   . ALA C 1 199 ? -27.520 -31.643 6.875   1.00 43.72  ? 199 ALA C N   1 
ATOM   8394  C CA  . ALA C 1 199 ? -27.882 -30.265 6.523   1.00 44.92  ? 199 ALA C CA  1 
ATOM   8395  C C   . ALA C 1 199 ? -28.132 -30.123 5.013   1.00 43.43  ? 199 ALA C C   1 
ATOM   8396  O O   . ALA C 1 199 ? -28.465 -29.030 4.550   1.00 40.64  ? 199 ALA C O   1 
ATOM   8397  C CB  . ALA C 1 199 ? -26.795 -29.294 6.988   1.00 46.69  ? 199 ALA C CB  1 
ATOM   8398  N N   . GLY C 1 200 ? -27.908 -31.211 4.248   1.00 41.28  ? 200 GLY C N   1 
ATOM   8399  C CA  . GLY C 1 200 ? -28.347 -31.282 2.855   1.00 37.69  ? 200 GLY C CA  1 
ATOM   8400  C C   . GLY C 1 200 ? -27.216 -30.980 1.868   1.00 42.11  ? 200 GLY C C   1 
ATOM   8401  O O   . GLY C 1 200 ? -27.470 -30.727 0.694   1.00 37.79  ? 200 GLY C O   1 
ATOM   8402  N N   . LEU C 1 201 ? -25.960 -31.097 2.318   1.00 41.54  ? 201 LEU C N   1 
ATOM   8403  C CA  . LEU C 1 201 ? -24.837 -30.968 1.406   1.00 40.21  ? 201 LEU C CA  1 
ATOM   8404  C C   . LEU C 1 201 ? -24.876 -32.115 0.376   1.00 36.67  ? 201 LEU C C   1 
ATOM   8405  O O   . LEU C 1 201 ? -24.968 -33.282 0.733   1.00 36.20  ? 201 LEU C O   1 
ATOM   8406  C CB  . LEU C 1 201 ? -23.519 -30.950 2.171   1.00 40.15  ? 201 LEU C CB  1 
ATOM   8407  C CG  . LEU C 1 201 ? -22.269 -30.608 1.333   1.00 42.91  ? 201 LEU C CG  1 
ATOM   8408  C CD1 . LEU C 1 201 ? -22.221 -29.111 1.004   1.00 41.37  ? 201 LEU C CD1 1 
ATOM   8409  C CD2 . LEU C 1 201 ? -20.981 -31.027 2.032   1.00 41.95  ? 201 LEU C CD2 1 
ATOM   8410  N N   . PRO C 1 202 ? -24.790 -31.820 -0.926  1.00 36.01  ? 202 PRO C N   1 
ATOM   8411  C CA  . PRO C 1 202 ? -24.739 -32.880 -1.932  1.00 36.18  ? 202 PRO C CA  1 
ATOM   8412  C C   . PRO C 1 202 ? -23.585 -33.864 -1.694  1.00 39.97  ? 202 PRO C C   1 
ATOM   8413  O O   . PRO C 1 202 ? -22.524 -33.475 -1.217  1.00 47.03  ? 202 PRO C O   1 
ATOM   8414  C CB  . PRO C 1 202 ? -24.585 -32.113 -3.268  1.00 36.70  ? 202 PRO C CB  1 
ATOM   8415  C CG  . PRO C 1 202 ? -25.126 -30.690 -2.970  1.00 36.24  ? 202 PRO C CG  1 
ATOM   8416  C CD  . PRO C 1 202 ? -24.808 -30.453 -1.507  1.00 38.40  ? 202 PRO C CD  1 
ATOM   8417  N N   . ALA C 1 203 ? -23.810 -35.130 -2.072  1.00 39.77  ? 203 ALA C N   1 
ATOM   8418  C CA  . ALA C 1 203 ? -22.843 -36.206 -1.894  1.00 41.28  ? 203 ALA C CA  1 
ATOM   8419  C C   . ALA C 1 203 ? -21.632 -36.003 -2.802  1.00 39.31  ? 203 ALA C C   1 
ATOM   8420  O O   . ALA C 1 203 ? -21.786 -35.668 -3.962  1.00 45.85  ? 203 ALA C O   1 
ATOM   8421  C CB  . ALA C 1 203 ? -23.509 -37.529 -2.184  1.00 40.97  ? 203 ALA C CB  1 
ATOM   8422  N N   . GLY C 1 204 ? -20.428 -36.225 -2.252  1.00 34.75  ? 204 GLY C N   1 
ATOM   8423  C CA  . GLY C 1 204 ? -19.195 -36.129 -3.020  1.00 34.50  ? 204 GLY C CA  1 
ATOM   8424  C C   . GLY C 1 204 ? -18.418 -34.828 -2.764  1.00 33.78  ? 204 GLY C C   1 
ATOM   8425  O O   . GLY C 1 204 ? -17.245 -34.735 -3.121  1.00 35.77  ? 204 GLY C O   1 
ATOM   8426  N N   . LEU C 1 205 ? -19.071 -33.824 -2.177  1.00 31.67  ? 205 LEU C N   1 
ATOM   8427  C CA  . LEU C 1 205 ? -18.421 -32.535 -1.923  1.00 32.36  ? 205 LEU C CA  1 
ATOM   8428  C C   . LEU C 1 205 ? -17.525 -32.598 -0.687  1.00 33.92  ? 205 LEU C C   1 
ATOM   8429  O O   . LEU C 1 205 ? -16.669 -31.731 -0.517  1.00 36.66  ? 205 LEU C O   1 
ATOM   8430  C CB  . LEU C 1 205 ? -19.470 -31.454 -1.743  1.00 39.14  ? 205 LEU C CB  1 
ATOM   8431  C CG  . LEU C 1 205 ? -20.233 -31.026 -3.005  1.00 41.37  ? 205 LEU C CG  1 
ATOM   8432  C CD1 . LEU C 1 205 ? -21.436 -30.120 -2.616  1.00 41.43  ? 205 LEU C CD1 1 
ATOM   8433  C CD2 . LEU C 1 205 ? -19.312 -30.328 -3.952  1.00 36.70  ? 205 LEU C CD2 1 
ATOM   8434  N N   . PHE C 1 206 ? -17.795 -33.562 0.225   1.00 33.34  ? 206 PHE C N   1 
ATOM   8435  C CA  . PHE C 1 206 ? -17.047 -33.684 1.480   1.00 32.80  ? 206 PHE C CA  1 
ATOM   8436  C C   . PHE C 1 206 ? -16.654 -35.158 1.688   1.00 36.67  ? 206 PHE C C   1 
ATOM   8437  O O   . PHE C 1 206 ? -17.494 -35.987 2.049   1.00 34.21  ? 206 PHE C O   1 
ATOM   8438  C CB  . PHE C 1 206 ? -17.905 -33.130 2.617   1.00 29.79  ? 206 PHE C CB  1 
ATOM   8439  C CG  . PHE C 1 206 ? -17.249 -32.993 3.980   1.00 32.30  ? 206 PHE C CG  1 
ATOM   8440  C CD1 . PHE C 1 206 ? -15.966 -33.497 4.230   1.00 39.75  ? 206 PHE C CD1 1 
ATOM   8441  C CD2 . PHE C 1 206 ? -17.955 -32.431 5.048   1.00 33.77  ? 206 PHE C CD2 1 
ATOM   8442  C CE1 . PHE C 1 206 ? -15.395 -33.422 5.518   1.00 34.98  ? 206 PHE C CE1 1 
ATOM   8443  C CE2 . PHE C 1 206 ? -17.379 -32.336 6.313   1.00 35.88  ? 206 PHE C CE2 1 
ATOM   8444  C CZ  . PHE C 1 206 ? -16.093 -32.847 6.543   1.00 34.27  ? 206 PHE C CZ  1 
ATOM   8445  N N   . SER C 1 207 ? -15.356 -35.462 1.492   1.00 35.96  ? 207 SER C N   1 
ATOM   8446  C CA  . SER C 1 207 ? -14.812 -36.791 1.792   1.00 35.71  ? 207 SER C CA  1 
ATOM   8447  C C   . SER C 1 207 ? -13.828 -36.732 2.968   1.00 34.76  ? 207 SER C C   1 
ATOM   8448  O O   . SER C 1 207 ? -13.099 -35.740 3.159   1.00 37.78  ? 207 SER C O   1 
ATOM   8449  C CB  . SER C 1 207 ? -14.142 -37.401 0.586   1.00 39.13  ? 207 SER C CB  1 
ATOM   8450  O OG  . SER C 1 207 ? -15.053 -38.125 -0.226  1.00 35.50  ? 207 SER C OG  1 
ATOM   8451  N N   . VAL C 1 208 ? -13.789 -37.823 3.722   1.00 32.97  ? 208 VAL C N   1 
ATOM   8452  C CA  . VAL C 1 208 ? -12.825 -37.992 4.783   1.00 35.40  ? 208 VAL C CA  1 
ATOM   8453  C C   . VAL C 1 208 ? -12.029 -39.272 4.521   1.00 37.87  ? 208 VAL C C   1 
ATOM   8454  O O   . VAL C 1 208 ? -12.602 -40.324 4.231   1.00 37.24  ? 208 VAL C O   1 
ATOM   8455  C CB  . VAL C 1 208 ? -13.511 -38.023 6.150   1.00 34.17  ? 208 VAL C CB  1 
ATOM   8456  C CG1 . VAL C 1 208 ? -12.509 -38.238 7.275   1.00 36.26  ? 208 VAL C CG1 1 
ATOM   8457  C CG2 . VAL C 1 208 ? -14.316 -36.759 6.401   1.00 32.53  ? 208 VAL C CG2 1 
ATOM   8458  N N   . VAL C 1 209 ? -10.706 -39.158 4.598   1.00 37.11  ? 209 VAL C N   1 
ATOM   8459  C CA  . VAL C 1 209 ? -9.822  -40.260 4.301   1.00 38.25  ? 209 VAL C CA  1 
ATOM   8460  C C   . VAL C 1 209 ? -9.014  -40.572 5.557   1.00 35.59  ? 209 VAL C C   1 
ATOM   8461  O O   . VAL C 1 209 ? -8.150  -39.800 5.936   1.00 35.54  ? 209 VAL C O   1 
ATOM   8462  C CB  . VAL C 1 209 ? -8.904  -39.929 3.105   1.00 41.52  ? 209 VAL C CB  1 
ATOM   8463  C CG1 . VAL C 1 209 ? -8.102  -41.126 2.662   1.00 49.86  ? 209 VAL C CG1 1 
ATOM   8464  C CG2 . VAL C 1 209 ? -9.672  -39.367 1.925   1.00 44.19  ? 209 VAL C CG2 1 
ATOM   8465  N N   . VAL C 1 210 ? -9.288  -41.733 6.166   1.00 35.07  ? 210 VAL C N   1 
ATOM   8466  C CA  . VAL C 1 210 ? -8.559  -42.193 7.347   1.00 36.97  ? 210 VAL C CA  1 
ATOM   8467  C C   . VAL C 1 210 ? -7.677  -43.373 6.960   1.00 41.18  ? 210 VAL C C   1 
ATOM   8468  O O   . VAL C 1 210 ? -8.180  -44.461 6.695   1.00 46.51  ? 210 VAL C O   1 
ATOM   8469  C CB  . VAL C 1 210 ? -9.521  -42.602 8.474   1.00 39.34  ? 210 VAL C CB  1 
ATOM   8470  C CG1 . VAL C 1 210 ? -8.771  -43.025 9.753   1.00 37.45  ? 210 VAL C CG1 1 
ATOM   8471  C CG2 . VAL C 1 210 ? -10.546 -41.513 8.772   1.00 42.11  ? 210 VAL C CG2 1 
ATOM   8472  N N   . GLY C 1 211 ? -6.361  -43.169 6.994   1.00 47.83  ? 211 GLY C N   1 
ATOM   8473  C CA  . GLY C 1 211 ? -5.428  -44.163 6.490   1.00 54.43  ? 211 GLY C CA  1 
ATOM   8474  C C   . GLY C 1 211 ? -4.084  -44.135 7.225   1.00 56.94  ? 211 GLY C C   1 
ATOM   8475  O O   . GLY C 1 211 ? -3.823  -43.243 8.026   1.00 48.84  ? 211 GLY C O   1 
ATOM   8476  N N   . PRO C 1 212 ? -3.218  -45.159 7.008   1.00 75.70  ? 212 PRO C N   1 
ATOM   8477  C CA  . PRO C 1 212 ? -1.898  -45.198 7.626   1.00 81.01  ? 212 PRO C CA  1 
ATOM   8478  C C   . PRO C 1 212 ? -1.024  -44.112 7.037   1.00 85.68  ? 212 PRO C C   1 
ATOM   8479  O O   . PRO C 1 212 ? -0.900  -44.004 5.815   1.00 87.38  ? 212 PRO C O   1 
ATOM   8480  C CB  . PRO C 1 212 ? -1.354  -46.620 7.325   1.00 84.08  ? 212 PRO C CB  1 
ATOM   8481  C CG  . PRO C 1 212 ? -2.573  -47.399 6.813   1.00 89.25  ? 212 PRO C CG  1 
ATOM   8482  C CD  . PRO C 1 212 ? -3.506  -46.359 6.217   1.00 86.66  ? 212 PRO C CD  1 
ATOM   8483  N N   . GLY C 1 213 ? -0.419  -43.312 7.918   1.00 99.84  ? 213 GLY C N   1 
ATOM   8484  C CA  . GLY C 1 213 ? 0.367   -42.158 7.506   1.00 112.19 ? 213 GLY C CA  1 
ATOM   8485  C C   . GLY C 1 213 ? 1.459   -42.540 6.499   1.00 120.12 ? 213 GLY C C   1 
ATOM   8486  O O   . GLY C 1 213 ? 1.963   -41.675 5.771   1.00 110.46 ? 213 GLY C O   1 
ATOM   8487  N N   . SER C 1 214 ? 1.831   -43.847 6.483   1.00 133.36 ? 214 SER C N   1 
ATOM   8488  C CA  . SER C 1 214 ? 2.930   -44.335 5.655   1.00 131.81 ? 214 SER C CA  1 
ATOM   8489  C C   . SER C 1 214 ? 2.548   -44.284 4.171   1.00 115.57 ? 214 SER C C   1 
ATOM   8490  O O   . SER C 1 214 ? 3.212   -43.602 3.401   1.00 129.18 ? 214 SER C O   1 
ATOM   8491  C CB  . SER C 1 214 ? 3.395   -45.735 6.079   1.00 126.52 ? 214 SER C CB  1 
ATOM   8492  O OG  . SER C 1 214 ? 2.380   -46.710 5.898   1.00 126.22 ? 214 SER C OG  1 
ATOM   8493  N N   . GLU C 1 215 ? 1.473   -44.987 3.765   1.00 93.49  ? 215 GLU C N   1 
ATOM   8494  C CA  . GLU C 1 215 ? 1.144   -45.031 2.344   1.00 100.48 ? 215 GLU C CA  1 
ATOM   8495  C C   . GLU C 1 215 ? 0.501   -43.690 1.901   1.00 98.01  ? 215 GLU C C   1 
ATOM   8496  O O   . GLU C 1 215 ? 1.055   -42.993 1.042   1.00 107.39 ? 215 GLU C O   1 
ATOM   8497  C CB  . GLU C 1 215 ? 0.380   -46.285 1.897   1.00 110.80 ? 215 GLU C CB  1 
ATOM   8498  C CG  . GLU C 1 215 ? -0.762  -46.742 2.809   1.00 117.92 ? 215 GLU C CG  1 
ATOM   8499  C CD  . GLU C 1 215 ? -1.777  -47.646 2.092   1.00 131.30 ? 215 GLU C CD  1 
ATOM   8500  O OE1 . GLU C 1 215 ? -2.552  -48.349 2.771   1.00 131.82 ? 215 GLU C OE1 1 
ATOM   8501  O OE2 . GLU C 1 215 ? -1.781  -47.644 0.839   1.00 130.98 ? 215 GLU C OE2 1 
ATOM   8502  N N   . ILE C 1 216 ? -0.652  -43.316 2.479   1.00 79.00  ? 216 ILE C N   1 
ATOM   8503  C CA  . ILE C 1 216 ? -1.458  -42.257 1.876   1.00 61.22  ? 216 ILE C CA  1 
ATOM   8504  C C   . ILE C 1 216 ? -1.001  -40.871 2.375   1.00 55.20  ? 216 ILE C C   1 
ATOM   8505  O O   . ILE C 1 216 ? -1.479  -39.863 1.885   1.00 50.72  ? 216 ILE C O   1 
ATOM   8506  C CB  . ILE C 1 216 ? -2.959  -42.473 2.112   1.00 62.57  ? 216 ILE C CB  1 
ATOM   8507  C CG1 . ILE C 1 216 ? -3.327  -42.303 3.555   1.00 62.51  ? 216 ILE C CG1 1 
ATOM   8508  C CG2 . ILE C 1 216 ? -3.428  -43.827 1.550   1.00 70.99  ? 216 ILE C CG2 1 
ATOM   8509  C CD1 . ILE C 1 216 ? -4.687  -41.677 3.760   1.00 64.97  ? 216 ILE C CD1 1 
ATOM   8510  N N   . GLY C 1 217 ? -0.068  -40.830 3.336   1.00 53.46  ? 217 GLY C N   1 
ATOM   8511  C CA  . GLY C 1 217 ? 0.357   -39.572 3.950   1.00 48.48  ? 217 GLY C CA  1 
ATOM   8512  C C   . GLY C 1 217 ? 0.869   -38.555 2.910   1.00 52.48  ? 217 GLY C C   1 
ATOM   8513  O O   . GLY C 1 217 ? 0.295   -37.480 2.742   1.00 55.89  ? 217 GLY C O   1 
ATOM   8514  N N   . ASP C 1 218 ? 1.972   -38.895 2.249   1.00 49.04  ? 218 ASP C N   1 
ATOM   8515  C CA  . ASP C 1 218 ? 2.574   -38.031 1.241   1.00 51.33  ? 218 ASP C CA  1 
ATOM   8516  C C   . ASP C 1 218 ? 1.637   -37.868 0.034   1.00 43.15  ? 218 ASP C C   1 
ATOM   8517  O O   . ASP C 1 218 ? 1.616   -36.822 -0.614  1.00 52.19  ? 218 ASP C O   1 
ATOM   8518  C CB  . ASP C 1 218 ? 3.929   -38.568 0.794   1.00 53.81  ? 218 ASP C CB  1 
ATOM   8519  C CG  . ASP C 1 218 ? 5.069   -38.417 1.798   1.00 58.53  ? 218 ASP C CG  1 
ATOM   8520  O OD1 . ASP C 1 218 ? 4.827   -37.865 2.914   1.00 58.83  ? 218 ASP C OD1 1 
ATOM   8521  O OD2 . ASP C 1 218 ? 6.200   -38.823 1.450   1.00 68.38  ? 218 ASP C OD2 1 
ATOM   8522  N N   . ALA C 1 219 ? 0.893   -38.900 -0.279  1.00 38.08  ? 219 ALA C N   1 
ATOM   8523  C CA  . ALA C 1 219 ? 0.064   -38.889 -1.473  1.00 40.15  ? 219 ALA C CA  1 
ATOM   8524  C C   . ALA C 1 219 ? -1.032  -37.810 -1.363  1.00 38.14  ? 219 ALA C C   1 
ATOM   8525  O O   . ALA C 1 219 ? -1.420  -37.244 -2.360  1.00 37.34  ? 219 ALA C O   1 
ATOM   8526  C CB  . ALA C 1 219 ? -0.528  -40.279 -1.710  1.00 34.94  ? 219 ALA C CB  1 
ATOM   8527  N N   . PHE C 1 220 ? -1.549  -37.581 -0.139  1.00 38.65  ? 220 PHE C N   1 
ATOM   8528  C CA  . PHE C 1 220 ? -2.590  -36.582 0.099   1.00 38.18  ? 220 PHE C CA  1 
ATOM   8529  C C   . PHE C 1 220 ? -2.101  -35.206 -0.350  1.00 36.64  ? 220 PHE C C   1 
ATOM   8530  O O   . PHE C 1 220 ? -2.828  -34.462 -1.004  1.00 36.94  ? 220 PHE C O   1 
ATOM   8531  C CB  . PHE C 1 220 ? -2.987  -36.578 1.576   1.00 37.70  ? 220 PHE C CB  1 
ATOM   8532  C CG  . PHE C 1 220 ? -4.179  -35.696 1.896   1.00 41.38  ? 220 PHE C CG  1 
ATOM   8533  C CD1 . PHE C 1 220 ? -5.483  -36.166 1.747   1.00 43.24  ? 220 PHE C CD1 1 
ATOM   8534  C CD2 . PHE C 1 220 ? -4.000  -34.386 2.342   1.00 44.81  ? 220 PHE C CD2 1 
ATOM   8535  C CE1 . PHE C 1 220 ? -6.564  -35.348 2.024   1.00 38.79  ? 220 PHE C CE1 1 
ATOM   8536  C CE2 . PHE C 1 220 ? -5.092  -33.577 2.643   1.00 39.91  ? 220 PHE C CE2 1 
ATOM   8537  C CZ  . PHE C 1 220 ? -6.358  -34.054 2.494   1.00 40.98  ? 220 PHE C CZ  1 
ATOM   8538  N N   . VAL C 1 221 ? -0.863  -34.886 -0.015  1.00 40.42  ? 221 VAL C N   1 
ATOM   8539  C CA  . VAL C 1 221 ? -0.314  -33.568 -0.300  1.00 46.48  ? 221 VAL C CA  1 
ATOM   8540  C C   . VAL C 1 221 ? 0.161   -33.505 -1.762  1.00 48.15  ? 221 VAL C C   1 
ATOM   8541  O O   . VAL C 1 221 ? -0.016  -32.479 -2.416  1.00 46.77  ? 221 VAL C O   1 
ATOM   8542  C CB  . VAL C 1 221 ? 0.805   -33.212 0.688   1.00 42.12  ? 221 VAL C CB  1 
ATOM   8543  C CG1 . VAL C 1 221 ? 1.283   -31.781 0.515   1.00 44.06  ? 221 VAL C CG1 1 
ATOM   8544  C CG2 . VAL C 1 221 ? 0.355   -33.429 2.114   1.00 41.96  ? 221 VAL C CG2 1 
ATOM   8545  N N   . GLU C 1 222 ? 0.684   -34.638 -2.279  1.00 46.97  ? 222 GLU C N   1 
ATOM   8546  C CA  . GLU C 1 222 ? 1.308   -34.694 -3.609  1.00 46.25  ? 222 GLU C CA  1 
ATOM   8547  C C   . GLU C 1 222 ? 0.255   -34.664 -4.733  1.00 40.82  ? 222 GLU C C   1 
ATOM   8548  O O   . GLU C 1 222 ? 0.591   -34.368 -5.883  1.00 42.82  ? 222 GLU C O   1 
ATOM   8549  C CB  . GLU C 1 222 ? 2.143   -35.972 -3.775  1.00 53.34  ? 222 GLU C CB  1 
ATOM   8550  C CG  . GLU C 1 222 ? 3.618   -35.815 -3.408  1.00 57.63  ? 222 GLU C CG  1 
ATOM   8551  C CD  . GLU C 1 222 ? 4.332   -37.132 -3.086  1.00 64.62  ? 222 GLU C CD  1 
ATOM   8552  O OE1 . GLU C 1 222 ? 3.681   -38.221 -3.175  1.00 60.00  ? 222 GLU C OE1 1 
ATOM   8553  O OE2 . GLU C 1 222 ? 5.536   -37.078 -2.723  1.00 67.43  ? 222 GLU C OE2 1 
ATOM   8554  N N   . HIS C 1 223 ? -1.007  -35.001 -4.409  1.00 36.64  ? 223 HIS C N   1 
ATOM   8555  C CA  . HIS C 1 223 ? -2.021  -35.306 -5.432  1.00 37.38  ? 223 HIS C CA  1 
ATOM   8556  C C   . HIS C 1 223 ? -2.268  -34.088 -6.330  1.00 38.73  ? 223 HIS C C   1 
ATOM   8557  O O   . HIS C 1 223 ? -2.252  -32.961 -5.878  1.00 39.27  ? 223 HIS C O   1 
ATOM   8558  C CB  . HIS C 1 223 ? -3.336  -35.741 -4.772  1.00 41.17  ? 223 HIS C CB  1 
ATOM   8559  C CG  . HIS C 1 223 ? -4.210  -36.600 -5.631  1.00 41.84  ? 223 HIS C CG  1 
ATOM   8560  N ND1 . HIS C 1 223 ? -4.990  -36.113 -6.656  1.00 43.32  ? 223 HIS C ND1 1 
ATOM   8561  C CD2 . HIS C 1 223 ? -4.429  -37.908 -5.595  1.00 41.53  ? 223 HIS C CD2 1 
ATOM   8562  C CE1 . HIS C 1 223 ? -5.642  -37.115 -7.214  1.00 41.27  ? 223 HIS C CE1 1 
ATOM   8563  N NE2 . HIS C 1 223 ? -5.321  -38.208 -6.582  1.00 42.46  ? 223 HIS C NE2 1 
ATOM   8564  N N   . PRO C 1 224 ? -2.552  -34.290 -7.625  1.00 45.54  ? 224 PRO C N   1 
ATOM   8565  C CA  . PRO C 1 224 ? -2.746  -33.162 -8.548  1.00 47.18  ? 224 PRO C CA  1 
ATOM   8566  C C   . PRO C 1 224 ? -4.057  -32.369 -8.505  1.00 45.99  ? 224 PRO C C   1 
ATOM   8567  O O   . PRO C 1 224 ? -4.069  -31.211 -8.908  1.00 43.58  ? 224 PRO C O   1 
ATOM   8568  C CB  . PRO C 1 224 ? -2.550  -33.847 -9.930  1.00 46.63  ? 224 PRO C CB  1 
ATOM   8569  C CG  . PRO C 1 224 ? -2.952  -35.268 -9.684  1.00 47.99  ? 224 PRO C CG  1 
ATOM   8570  C CD  . PRO C 1 224 ? -2.409  -35.569 -8.321  1.00 47.34  ? 224 PRO C CD  1 
ATOM   8571  N N   . VAL C 1 225 ? -5.166  -32.985 -8.057  1.00 47.30  ? 225 VAL C N   1 
ATOM   8572  C CA  . VAL C 1 225 ? -6.467  -32.303 -8.145  1.00 47.90  ? 225 VAL C CA  1 
ATOM   8573  C C   . VAL C 1 225 ? -6.529  -31.111 -7.137  1.00 47.93  ? 225 VAL C C   1 
ATOM   8574  O O   . VAL C 1 225 ? -7.002  -30.033 -7.493  1.00 46.95  ? 225 VAL C O   1 
ATOM   8575  C CB  . VAL C 1 225 ? -7.715  -33.207 -8.017  1.00 50.20  ? 225 VAL C CB  1 
ATOM   8576  C CG1 . VAL C 1 225 ? -7.521  -34.570 -8.690  1.00 50.88  ? 225 VAL C CG1 1 
ATOM   8577  C CG2 . VAL C 1 225 ? -8.172  -33.368 -6.599  1.00 48.46  ? 225 VAL C CG2 1 
ATOM   8578  N N   . PRO C 1 226 ? -6.083  -31.232 -5.864  1.00 44.85  ? 226 PRO C N   1 
ATOM   8579  C CA  . PRO C 1 226 ? -6.360  -30.190 -4.894  1.00 42.39  ? 226 PRO C CA  1 
ATOM   8580  C C   . PRO C 1 226 ? -5.676  -28.910 -5.282  1.00 42.69  ? 226 PRO C C   1 
ATOM   8581  O O   . PRO C 1 226 ? -4.496  -28.900 -5.547  1.00 48.02  ? 226 PRO C O   1 
ATOM   8582  C CB  . PRO C 1 226 ? -5.839  -30.756 -3.576  1.00 42.92  ? 226 PRO C CB  1 
ATOM   8583  C CG  . PRO C 1 226 ? -4.803  -31.762 -3.994  1.00 44.61  ? 226 PRO C CG  1 
ATOM   8584  C CD  . PRO C 1 226 ? -5.341  -32.365 -5.278  1.00 46.65  ? 226 PRO C CD  1 
ATOM   8585  N N   . GLY C 1 227 ? -6.427  -27.824 -5.281  1.00 45.66  ? 227 GLY C N   1 
ATOM   8586  C CA  . GLY C 1 227 ? -5.876  -26.519 -5.614  1.00 41.57  ? 227 GLY C CA  1 
ATOM   8587  C C   . GLY C 1 227 ? -5.182  -25.880 -4.420  1.00 40.28  ? 227 GLY C C   1 
ATOM   8588  O O   . GLY C 1 227 ? -4.335  -25.032 -4.594  1.00 45.11  ? 227 GLY C O   1 
ATOM   8589  N N   . LEU C 1 228 ? -5.595  -26.262 -3.205  1.00 38.60  ? 228 LEU C N   1 
ATOM   8590  C CA  . LEU C 1 228 ? -5.024  -25.707 -1.983  1.00 35.99  ? 228 LEU C CA  1 
ATOM   8591  C C   . LEU C 1 228 ? -4.922  -26.820 -0.953  1.00 36.33  ? 228 LEU C C   1 
ATOM   8592  O O   . LEU C 1 228 ? -5.787  -27.681 -0.890  1.00 39.72  ? 228 LEU C O   1 
ATOM   8593  C CB  . LEU C 1 228 ? -5.913  -24.561 -1.499  1.00 34.14  ? 228 LEU C CB  1 
ATOM   8594  C CG  . LEU C 1 228 ? -5.519  -23.900 -0.180  1.00 37.48  ? 228 LEU C CG  1 
ATOM   8595  C CD1 . LEU C 1 228 ? -4.181  -23.215 -0.265  1.00 39.83  ? 228 LEU C CD1 1 
ATOM   8596  C CD2 . LEU C 1 228 ? -6.590  -22.921 0.268   1.00 35.40  ? 228 LEU C CD2 1 
ATOM   8597  N N   . VAL C 1 229 ? -3.857  -26.791 -0.150  1.00 37.95  ? 229 VAL C N   1 
ATOM   8598  C CA  . VAL C 1 229 ? -3.735  -27.669 1.004   1.00 38.83  ? 229 VAL C CA  1 
ATOM   8599  C C   . VAL C 1 229 ? -3.603  -26.803 2.255   1.00 38.08  ? 229 VAL C C   1 
ATOM   8600  O O   . VAL C 1 229 ? -2.818  -25.860 2.282   1.00 39.40  ? 229 VAL C O   1 
ATOM   8601  C CB  . VAL C 1 229 ? -2.554  -28.657 0.870   1.00 44.27  ? 229 VAL C CB  1 
ATOM   8602  C CG1 . VAL C 1 229 ? -2.309  -29.450 2.148   1.00 48.99  ? 229 VAL C CG1 1 
ATOM   8603  C CG2 . VAL C 1 229 ? -2.746  -29.610 -0.288  1.00 46.41  ? 229 VAL C CG2 1 
ATOM   8604  N N   . THR C 1 230 ? -4.341  -27.179 3.300   1.00 38.04  ? 230 THR C N   1 
ATOM   8605  C CA  . THR C 1 230 ? -4.449  -26.389 4.524   1.00 43.75  ? 230 THR C CA  1 
ATOM   8606  C C   . THR C 1 230 ? -3.972  -27.238 5.709   1.00 43.97  ? 230 THR C C   1 
ATOM   8607  O O   . THR C 1 230 ? -4.318  -28.421 5.799   1.00 43.73  ? 230 THR C O   1 
ATOM   8608  C CB  . THR C 1 230 ? -5.916  -25.959 4.695   1.00 47.52  ? 230 THR C CB  1 
ATOM   8609  O OG1 . THR C 1 230 ? -6.119  -24.783 3.915   1.00 46.84  ? 230 THR C OG1 1 
ATOM   8610  C CG2 . THR C 1 230 ? -6.273  -25.675 6.132   1.00 54.94  ? 230 THR C CG2 1 
ATOM   8611  N N   . PHE C 1 231 ? -3.259  -26.594 6.665   1.00 40.52  ? 231 PHE C N   1 
ATOM   8612  C CA  . PHE C 1 231 ? -2.809  -27.265 7.876   1.00 42.20  ? 231 PHE C CA  1 
ATOM   8613  C C   . PHE C 1 231 ? -2.563  -26.250 8.984   1.00 48.92  ? 231 PHE C C   1 
ATOM   8614  O O   . PHE C 1 231 ? -1.872  -25.253 8.776   1.00 46.58  ? 231 PHE C O   1 
ATOM   8615  C CB  . PHE C 1 231 ? -1.509  -28.046 7.677   1.00 42.56  ? 231 PHE C CB  1 
ATOM   8616  C CG  . PHE C 1 231 ? -0.976  -28.648 8.964   1.00 49.23  ? 231 PHE C CG  1 
ATOM   8617  C CD1 . PHE C 1 231 ? -1.614  -29.739 9.568   1.00 56.60  ? 231 PHE C CD1 1 
ATOM   8618  C CD2 . PHE C 1 231 ? 0.132   -28.103 9.598   1.00 55.49  ? 231 PHE C CD2 1 
ATOM   8619  C CE1 . PHE C 1 231 ? -1.140  -30.267 10.769  1.00 57.03  ? 231 PHE C CE1 1 
ATOM   8620  C CE2 . PHE C 1 231 ? 0.610   -28.647 10.782  1.00 56.28  ? 231 PHE C CE2 1 
ATOM   8621  C CZ  . PHE C 1 231 ? -0.038  -29.723 11.370  1.00 56.12  ? 231 PHE C CZ  1 
ATOM   8622  N N   . THR C 1 232 ? -3.084  -26.565 10.187  1.00 54.52  ? 232 THR C N   1 
ATOM   8623  C CA  . THR C 1 232 ? -2.720  -25.875 11.419  1.00 59.45  ? 232 THR C CA  1 
ATOM   8624  C C   . THR C 1 232 ? -2.254  -26.914 12.443  1.00 63.65  ? 232 THR C C   1 
ATOM   8625  O O   . THR C 1 232 ? -2.949  -27.900 12.677  1.00 67.29  ? 232 THR C O   1 
ATOM   8626  C CB  . THR C 1 232 ? -3.919  -25.077 11.929  1.00 60.46  ? 232 THR C CB  1 
ATOM   8627  O OG1 . THR C 1 232 ? -4.807  -26.025 12.519  1.00 75.49  ? 232 THR C OG1 1 
ATOM   8628  C CG2 . THR C 1 232 ? -4.639  -24.331 10.817  1.00 64.63  ? 232 THR C CG2 1 
ATOM   8629  N N   . GLY C 1 233 ? -1.049  -26.704 13.018  1.00 64.06  ? 233 GLY C N   1 
ATOM   8630  C CA  . GLY C 1 233 ? -0.537  -27.573 14.079  1.00 60.54  ? 233 GLY C CA  1 
ATOM   8631  C C   . GLY C 1 233 ? 0.983   -27.424 14.285  1.00 68.33  ? 233 GLY C C   1 
ATOM   8632  O O   . GLY C 1 233 ? 1.526   -26.327 14.194  1.00 76.06  ? 233 GLY C O   1 
ATOM   8633  N N   . SER C 1 234 ? 1.656   -28.553 14.574  1.00 70.62  ? 234 SER C N   1 
ATOM   8634  C CA  . SER C 1 234 ? 3.043   -28.540 15.011  1.00 70.34  ? 234 SER C CA  1 
ATOM   8635  C C   . SER C 1 234 ? 3.944   -28.098 13.866  1.00 76.55  ? 234 SER C C   1 
ATOM   8636  O O   . SER C 1 234 ? 3.663   -28.386 12.698  1.00 79.48  ? 234 SER C O   1 
ATOM   8637  C CB  . SER C 1 234 ? 3.472   -29.906 15.570  1.00 69.49  ? 234 SER C CB  1 
ATOM   8638  O OG  . SER C 1 234 ? 3.067   -30.972 14.724  1.00 59.56  ? 234 SER C OG  1 
ATOM   8639  N N   . THR C 1 235 ? 5.037   -27.401 14.227  1.00 80.24  ? 235 THR C N   1 
ATOM   8640  C CA  . THR C 1 235 ? 6.019   -26.905 13.263  1.00 75.99  ? 235 THR C CA  1 
ATOM   8641  C C   . THR C 1 235 ? 6.672   -28.078 12.513  1.00 80.43  ? 235 THR C C   1 
ATOM   8642  O O   . THR C 1 235 ? 6.789   -28.027 11.293  1.00 81.67  ? 235 THR C O   1 
ATOM   8643  C CB  . THR C 1 235 ? 7.063   -26.026 13.971  1.00 69.59  ? 235 THR C CB  1 
ATOM   8644  O OG1 . THR C 1 235 ? 6.350   -24.858 14.381  1.00 70.31  ? 235 THR C OG1 1 
ATOM   8645  C CG2 . THR C 1 235 ? 8.233   -25.647 13.068  1.00 56.99  ? 235 THR C CG2 1 
ATOM   8646  N N   . PRO C 1 236 ? 7.150   -29.155 13.198  1.00 86.96  ? 236 PRO C N   1 
ATOM   8647  C CA  . PRO C 1 236 ? 7.798   -30.267 12.491  1.00 82.35  ? 236 PRO C CA  1 
ATOM   8648  C C   . PRO C 1 236 ? 6.891   -30.923 11.445  1.00 73.83  ? 236 PRO C C   1 
ATOM   8649  O O   . PRO C 1 236 ? 7.338   -31.220 10.339  1.00 68.12  ? 236 PRO C O   1 
ATOM   8650  C CB  . PRO C 1 236 ? 8.190   -31.242 13.620  1.00 86.80  ? 236 PRO C CB  1 
ATOM   8651  C CG  . PRO C 1 236 ? 7.274   -30.863 14.781  1.00 89.47  ? 236 PRO C CG  1 
ATOM   8652  C CD  . PRO C 1 236 ? 7.097   -29.362 14.654  1.00 86.86  ? 236 PRO C CD  1 
ATOM   8653  N N   . VAL C 1 237 ? 5.607   -31.122 11.798  1.00 68.69  ? 237 VAL C N   1 
ATOM   8654  C CA  . VAL C 1 237 ? 4.640   -31.704 10.872  1.00 65.13  ? 237 VAL C CA  1 
ATOM   8655  C C   . VAL C 1 237 ? 4.422   -30.743 9.698   1.00 61.05  ? 237 VAL C C   1 
ATOM   8656  O O   . VAL C 1 237 ? 4.460   -31.158 8.535   1.00 56.15  ? 237 VAL C O   1 
ATOM   8657  C CB  . VAL C 1 237 ? 3.310   -32.050 11.559  1.00 59.44  ? 237 VAL C CB  1 
ATOM   8658  C CG1 . VAL C 1 237 ? 2.240   -32.431 10.555  1.00 58.59  ? 237 VAL C CG1 1 
ATOM   8659  C CG2 . VAL C 1 237 ? 3.483   -33.154 12.568  1.00 58.22  ? 237 VAL C CG2 1 
ATOM   8660  N N   . GLY C 1 238 ? 4.203   -29.461 10.018  1.00 61.63  ? 238 GLY C N   1 
ATOM   8661  C CA  . GLY C 1 238 ? 3.934   -28.449 9.013   1.00 58.53  ? 238 GLY C CA  1 
ATOM   8662  C C   . GLY C 1 238 ? 5.090   -28.305 8.030   1.00 56.57  ? 238 GLY C C   1 
ATOM   8663  O O   . GLY C 1 238 ? 4.873   -28.110 6.831   1.00 54.23  ? 238 GLY C O   1 
ATOM   8664  N N   . ARG C 1 239 ? 6.320   -28.413 8.543   1.00 60.15  ? 239 ARG C N   1 
ATOM   8665  C CA  . ARG C 1 239 ? 7.510   -28.341 7.704   1.00 60.75  ? 239 ARG C CA  1 
ATOM   8666  C C   . ARG C 1 239 ? 7.472   -29.465 6.677   1.00 58.19  ? 239 ARG C C   1 
ATOM   8667  O O   . ARG C 1 239 ? 7.815   -29.262 5.516   1.00 62.17  ? 239 ARG C O   1 
ATOM   8668  C CB  . ARG C 1 239 ? 8.787   -28.400 8.554   1.00 72.89  ? 239 ARG C CB  1 
ATOM   8669  C CG  . ARG C 1 239 ? 9.356   -27.025 8.893   1.00 90.09  ? 239 ARG C CG  1 
ATOM   8670  C CD  . ARG C 1 239 ? 10.755  -27.055 9.578   1.00 96.24  ? 239 ARG C CD  1 
ATOM   8671  N NE  . ARG C 1 239 ? 11.587  -28.213 9.216   1.00 102.44 ? 239 ARG C NE  1 
ATOM   8672  C CZ  . ARG C 1 239 ? 12.018  -28.528 7.984   1.00 110.33 ? 239 ARG C CZ  1 
ATOM   8673  N NH1 . ARG C 1 239 ? 11.729  -27.762 6.951   1.00 121.06 ? 239 ARG C NH1 1 
ATOM   8674  N NH2 . ARG C 1 239 ? 12.734  -29.620 7.796   1.00 116.19 ? 239 ARG C NH2 1 
ATOM   8675  N N   . ASN C 1 240 ? 7.053   -30.653 7.126   1.00 59.86  ? 240 ASN C N   1 
ATOM   8676  C CA  . ASN C 1 240 ? 6.961   -31.816 6.266   1.00 58.35  ? 240 ASN C CA  1 
ATOM   8677  C C   . ASN C 1 240 ? 5.988   -31.517 5.140   1.00 58.11  ? 240 ASN C C   1 
ATOM   8678  O O   . ASN C 1 240 ? 6.317   -31.691 3.972   1.00 58.02  ? 240 ASN C O   1 
ATOM   8679  C CB  . ASN C 1 240 ? 6.537   -33.064 7.042   1.00 65.06  ? 240 ASN C CB  1 
ATOM   8680  C CG  . ASN C 1 240 ? 7.261   -34.301 6.563   1.00 76.70  ? 240 ASN C CG  1 
ATOM   8681  O OD1 . ASN C 1 240 ? 8.410   -34.535 6.949   1.00 88.43  ? 240 ASN C OD1 1 
ATOM   8682  N ND2 . ASN C 1 240 ? 6.615   -35.104 5.731   1.00 86.87  ? 240 ASN C ND2 1 
ATOM   8683  N N   . ILE C 1 241 ? 4.794   -31.031 5.502   1.00 50.83  ? 241 ILE C N   1 
ATOM   8684  C CA  . ILE C 1 241 ? 3.765   -30.761 4.514   1.00 49.05  ? 241 ILE C CA  1 
ATOM   8685  C C   . ILE C 1 241 ? 4.305   -29.764 3.476   1.00 49.32  ? 241 ILE C C   1 
ATOM   8686  O O   . ILE C 1 241 ? 4.105   -29.947 2.272   1.00 47.28  ? 241 ILE C O   1 
ATOM   8687  C CB  . ILE C 1 241 ? 2.471   -30.268 5.188   1.00 50.70  ? 241 ILE C CB  1 
ATOM   8688  C CG1 . ILE C 1 241 ? 1.804   -31.407 6.024   1.00 48.41  ? 241 ILE C CG1 1 
ATOM   8689  C CG2 . ILE C 1 241 ? 1.499   -29.665 4.153   1.00 46.67  ? 241 ILE C CG2 1 
ATOM   8690  C CD1 . ILE C 1 241 ? 0.991   -30.916 7.212   1.00 47.05  ? 241 ILE C CD1 1 
ATOM   8691  N N   . GLY C 1 242 ? 5.004   -28.723 3.952   1.00 52.15  ? 242 GLY C N   1 
ATOM   8692  C CA  . GLY C 1 242 ? 5.566   -27.698 3.077   1.00 53.12  ? 242 GLY C CA  1 
ATOM   8693  C C   . GLY C 1 242 ? 6.561   -28.284 2.060   1.00 54.24  ? 242 GLY C C   1 
ATOM   8694  O O   . GLY C 1 242 ? 6.542   -27.921 0.884   1.00 54.58  ? 242 GLY C O   1 
ATOM   8695  N N   . ARG C 1 243 ? 7.400   -29.207 2.467   1.00 55.73  ? 243 ARG C N   1 
ATOM   8696  C CA  . ARG C 1 243 ? 8.412   -29.812 1.611   1.00 64.83  ? 243 ARG C CA  1 
ATOM   8697  C C   . ARG C 1 243 ? 7.751   -30.665 0.524   1.00 63.20  ? 243 ARG C C   1 
ATOM   8698  O O   . ARG C 1 243 ? 8.121   -30.559 -0.638  1.00 60.84  ? 243 ARG C O   1 
ATOM   8699  C CB  . ARG C 1 243 ? 9.382   -30.661 2.436   1.00 50.00  ? 243 ARG C CB  1 
ATOM   8700  C CG  . ARG C 1 243 ? 10.258  -29.858 3.382   1.00 50.00  ? 243 ARG C CG  1 
ATOM   8701  C CD  . ARG C 1 243 ? 11.255  -30.696 4.168   1.00 50.00  ? 243 ARG C CD  1 
ATOM   8702  N NE  . ARG C 1 243 ? 11.055  -32.126 3.957   1.00 50.00  ? 243 ARG C NE  1 
ATOM   8703  C CZ  . ARG C 1 243 ? 11.856  -33.068 4.431   1.00 50.00  ? 243 ARG C CZ  1 
ATOM   8704  N NH1 . ARG C 1 243 ? 12.919  -32.737 5.153   1.00 50.00  ? 243 ARG C NH1 1 
ATOM   8705  N NH2 . ARG C 1 243 ? 11.597  -34.347 4.189   1.00 50.00  ? 243 ARG C NH2 1 
ATOM   8706  N N   . ILE C 1 244 ? 6.821   -31.506 0.989   1.00 68.69  ? 244 ILE C N   1 
ATOM   8707  C CA  . ILE C 1 244 ? 6.128   -32.412 0.069   1.00 60.41  ? 244 ILE C CA  1 
ATOM   8708  C C   . ILE C 1 244 ? 5.406   -31.584 -0.987  1.00 59.16  ? 244 ILE C C   1 
ATOM   8709  O O   . ILE C 1 244 ? 5.360   -31.971 -2.142  1.00 65.49  ? 244 ILE C O   1 
ATOM   8710  C CB  . ILE C 1 244 ? 5.135   -33.344 0.803   1.00 65.41  ? 244 ILE C CB  1 
ATOM   8711  C CG1 . ILE C 1 244 ? 5.699   -33.901 2.112   1.00 72.38  ? 244 ILE C CG1 1 
ATOM   8712  C CG2 . ILE C 1 244 ? 4.660   -34.463 -0.120  1.00 66.19  ? 244 ILE C CG2 1 
ATOM   8713  C CD1 . ILE C 1 244 ? 6.609   -35.096 1.946   1.00 77.96  ? 244 ILE C CD1 1 
ATOM   8714  N N   . ALA C 1 245 ? 4.837   -30.440 -0.575  1.00 61.08  ? 245 ALA C N   1 
ATOM   8715  C CA  . ALA C 1 245 ? 4.101   -29.586 -1.495  1.00 66.74  ? 245 ALA C CA  1 
ATOM   8716  C C   . ALA C 1 245 ? 5.013   -29.144 -2.636  1.00 73.29  ? 245 ALA C C   1 
ATOM   8717  O O   . ALA C 1 245 ? 4.767   -29.494 -3.789  1.00 93.58  ? 245 ALA C O   1 
ATOM   8718  C CB  . ALA C 1 245 ? 3.489   -28.399 -0.764  1.00 67.00  ? 245 ALA C CB  1 
ATOM   8719  N N   . SER C 1 246 ? 6.072   -28.381 -2.313  1.00 91.27  ? 246 SER C N   1 
ATOM   8720  C CA  . SER C 1 246 ? 6.932   -27.800 -3.349  1.00 93.24  ? 246 SER C CA  1 
ATOM   8721  C C   . SER C 1 246 ? 7.905   -28.853 -3.914  1.00 88.80  ? 246 SER C C   1 
ATOM   8722  O O   . SER C 1 246 ? 8.228   -28.824 -5.098  1.00 93.07  ? 246 SER C O   1 
ATOM   8723  C CB  . SER C 1 246 ? 7.654   -26.614 -2.860  1.00 85.19  ? 246 SER C CB  1 
ATOM   8724  O OG  . SER C 1 246 ? 8.039   -25.806 -3.961  1.00 77.16  ? 246 SER C OG  1 
ATOM   8725  N N   . GLY C 1 247 ? 8.345   -29.787 -3.064  1.00 91.75  ? 247 GLY C N   1 
ATOM   8726  C CA  . GLY C 1 247 ? 9.223   -30.874 -3.494  1.00 92.32  ? 247 GLY C CA  1 
ATOM   8727  C C   . GLY C 1 247 ? 8.575   -31.734 -4.584  1.00 94.41  ? 247 GLY C C   1 
ATOM   8728  O O   . GLY C 1 247 ? 9.259   -32.236 -5.479  1.00 107.21 ? 247 GLY C O   1 
ATOM   8729  N N   . GLY C 1 248 ? 7.253   -31.898 -4.497  1.00 95.96  ? 248 GLY C N   1 
ATOM   8730  C CA  . GLY C 1 248 ? 6.529   -32.821 -5.359  1.00 92.81  ? 248 GLY C CA  1 
ATOM   8731  C C   . GLY C 1 248 ? 6.436   -32.308 -6.801  1.00 86.68  ? 248 GLY C C   1 
ATOM   8732  O O   . GLY C 1 248 ? 6.719   -31.133 -7.083  1.00 85.15  ? 248 GLY C O   1 
ATOM   8733  N N   . ALA C 1 249 ? 6.013   -33.210 -7.696  1.00 77.30  ? 249 ALA C N   1 
ATOM   8734  C CA  . ALA C 1 249 ? 5.878   -32.914 -9.116  1.00 79.11  ? 249 ALA C CA  1 
ATOM   8735  C C   . ALA C 1 249 ? 4.894   -31.758 -9.332  1.00 74.81  ? 249 ALA C C   1 
ATOM   8736  O O   . ALA C 1 249 ? 5.181   -30.831 -10.082 1.00 77.34  ? 249 ALA C O   1 
ATOM   8737  C CB  . ALA C 1 249 ? 5.439   -34.169 -9.866  1.00 70.30  ? 249 ALA C CB  1 
ATOM   8738  N N   . HIS C 1 250 ? 3.722   -31.843 -8.688  1.00 71.39  ? 250 HIS C N   1 
ATOM   8739  C CA  . HIS C 1 250 ? 2.690   -30.819 -8.828  1.00 73.29  ? 250 HIS C CA  1 
ATOM   8740  C C   . HIS C 1 250 ? 2.860   -29.781 -7.725  1.00 72.48  ? 250 HIS C C   1 
ATOM   8741  O O   . HIS C 1 250 ? 3.070   -30.129 -6.567  1.00 93.28  ? 250 HIS C O   1 
ATOM   8742  C CB  . HIS C 1 250 ? 1.295   -31.443 -8.800  1.00 69.40  ? 250 HIS C CB  1 
ATOM   8743  C CG  . HIS C 1 250 ? 1.209   -32.706 -9.564  1.00 72.87  ? 250 HIS C CG  1 
ATOM   8744  N ND1 . HIS C 1 250 ? 1.077   -33.936 -8.944  1.00 79.05  ? 250 HIS C ND1 1 
ATOM   8745  C CD2 . HIS C 1 250 ? 1.266   -32.953 -10.887 1.00 71.59  ? 250 HIS C CD2 1 
ATOM   8746  C CE1 . HIS C 1 250 ? 1.054   -34.888 -9.863  1.00 79.90  ? 250 HIS C CE1 1 
ATOM   8747  N NE2 . HIS C 1 250 ? 1.172   -34.314 -11.056 1.00 76.92  ? 250 HIS C NE2 1 
ATOM   8748  N N   . LEU C 1 251 ? 2.758   -28.511 -8.104  1.00 65.22  ? 251 LEU C N   1 
ATOM   8749  C CA  . LEU C 1 251 ? 2.905   -27.393 -7.177  1.00 70.75  ? 251 LEU C CA  1 
ATOM   8750  C C   . LEU C 1 251 ? 1.519   -26.830 -6.836  1.00 65.64  ? 251 LEU C C   1 
ATOM   8751  O O   . LEU C 1 251 ? 0.747   -26.520 -7.727  1.00 64.53  ? 251 LEU C O   1 
ATOM   8752  C CB  . LEU C 1 251 ? 3.804   -26.329 -7.819  1.00 73.56  ? 251 LEU C CB  1 
ATOM   8753  C CG  . LEU C 1 251 ? 5.313   -26.417 -7.513  1.00 87.62  ? 251 LEU C CG  1 
ATOM   8754  C CD1 . LEU C 1 251 ? 5.624   -25.730 -6.195  1.00 91.47  ? 251 LEU C CD1 1 
ATOM   8755  C CD2 . LEU C 1 251 ? 5.842   -27.863 -7.500  1.00 93.87  ? 251 LEU C CD2 1 
ATOM   8756  N N   . LYS C 1 252 ? 1.215   -26.717 -5.530  1.00 68.37  ? 252 LYS C N   1 
ATOM   8757  C CA  . LYS C 1 252 ? -0.027  -26.095 -5.071  1.00 61.14  ? 252 LYS C CA  1 
ATOM   8758  C C   . LYS C 1 252 ? 0.310   -25.019 -4.052  1.00 57.63  ? 252 LYS C C   1 
ATOM   8759  O O   . LYS C 1 252 ? 1.367   -25.047 -3.445  1.00 50.11  ? 252 LYS C O   1 
ATOM   8760  C CB  . LYS C 1 252 ? -0.996  -27.066 -4.370  1.00 64.79  ? 252 LYS C CB  1 
ATOM   8761  C CG  . LYS C 1 252 ? -1.121  -28.452 -4.949  1.00 82.52  ? 252 LYS C CG  1 
ATOM   8762  C CD  . LYS C 1 252 ? -0.077  -29.442 -4.459  1.00 85.58  ? 252 LYS C CD  1 
ATOM   8763  C CE  . LYS C 1 252 ? -0.163  -30.727 -5.212  1.00 85.61  ? 252 LYS C CE  1 
ATOM   8764  N NZ  . LYS C 1 252 ? 1.146   -31.368 -5.271  1.00 100.18 ? 252 LYS C NZ  1 
ATOM   8765  N N   . HIS C 1 253 ? -0.644  -24.131 -3.802  1.00 59.29  ? 253 HIS C N   1 
ATOM   8766  C CA  . HIS C 1 253 ? -0.588  -23.273 -2.637  1.00 61.54  ? 253 HIS C CA  1 
ATOM   8767  C C   . HIS C 1 253 ? -0.719  -24.118 -1.357  1.00 54.42  ? 253 HIS C C   1 
ATOM   8768  O O   . HIS C 1 253 ? -1.501  -25.070 -1.298  1.00 45.95  ? 253 HIS C O   1 
ATOM   8769  C CB  . HIS C 1 253 ? -1.636  -22.163 -2.745  1.00 68.43  ? 253 HIS C CB  1 
ATOM   8770  C CG  . HIS C 1 253 ? -1.279  -21.105 -3.748  1.00 87.59  ? 253 HIS C CG  1 
ATOM   8771  N ND1 . HIS C 1 253 ? -2.188  -20.203 -4.266  1.00 88.03  ? 253 HIS C ND1 1 
ATOM   8772  C CD2 . HIS C 1 253 ? -0.089  -20.794 -4.311  1.00 89.43  ? 253 HIS C CD2 1 
ATOM   8773  C CE1 . HIS C 1 253 ? -1.565  -19.388 -5.108  1.00 84.76  ? 253 HIS C CE1 1 
ATOM   8774  N NE2 . HIS C 1 253 ? -0.291  -19.728 -5.150  1.00 81.50  ? 253 HIS C NE2 1 
ATOM   8775  N N   . VAL C 1 254 ? 0.034   -23.723 -0.326  1.00 47.99  ? 254 VAL C N   1 
ATOM   8776  C CA  . VAL C 1 254 ? -0.155  -24.241 1.005   1.00 47.14  ? 254 VAL C CA  1 
ATOM   8777  C C   . VAL C 1 254 ? -0.444  -23.082 1.943   1.00 50.14  ? 254 VAL C C   1 
ATOM   8778  O O   . VAL C 1 254 ? 0.190   -22.045 1.865   1.00 56.54  ? 254 VAL C O   1 
ATOM   8779  C CB  . VAL C 1 254 ? 1.053   -25.041 1.488   1.00 54.91  ? 254 VAL C CB  1 
ATOM   8780  C CG1 . VAL C 1 254 ? 1.120   -26.413 0.830   1.00 69.61  ? 254 VAL C CG1 1 
ATOM   8781  C CG2 . VAL C 1 254 ? 2.351   -24.281 1.284   1.00 59.92  ? 254 VAL C CG2 1 
ATOM   8782  N N   . ALA C 1 255 ? -1.418  -23.285 2.826   1.00 46.94  ? 255 ALA C N   1 
ATOM   8783  C CA  . ALA C 1 255 ? -1.658  -22.395 3.935   1.00 44.35  ? 255 ALA C CA  1 
ATOM   8784  C C   . ALA C 1 255 ? -1.294  -23.121 5.251   1.00 48.70  ? 255 ALA C C   1 
ATOM   8785  O O   . ALA C 1 255 ? -1.959  -24.088 5.647   1.00 47.67  ? 255 ALA C O   1 
ATOM   8786  C CB  . ALA C 1 255 ? -3.120  -21.921 3.902   1.00 43.35  ? 255 ALA C CB  1 
ATOM   8787  N N   . LEU C 1 256 ? -0.194  -22.677 5.883   1.00 47.21  ? 256 LEU C N   1 
ATOM   8788  C CA  . LEU C 1 256 ? 0.305   -23.283 7.107   1.00 47.89  ? 256 LEU C CA  1 
ATOM   8789  C C   . LEU C 1 256 ? 0.171   -22.276 8.253   1.00 47.99  ? 256 LEU C C   1 
ATOM   8790  O O   . LEU C 1 256 ? 0.820   -21.249 8.243   1.00 54.31  ? 256 LEU C O   1 
ATOM   8791  C CB  . LEU C 1 256 ? 1.768   -23.717 6.930   1.00 49.13  ? 256 LEU C CB  1 
ATOM   8792  C CG  . LEU C 1 256 ? 2.050   -24.766 5.845   1.00 57.52  ? 256 LEU C CG  1 
ATOM   8793  C CD1 . LEU C 1 256 ? 3.545   -24.912 5.642   1.00 60.77  ? 256 LEU C CD1 1 
ATOM   8794  C CD2 . LEU C 1 256 ? 1.433   -26.126 6.158   1.00 60.30  ? 256 LEU C CD2 1 
ATOM   8795  N N   . GLU C 1 257 ? -0.662  -22.602 9.239   1.00 52.37  ? 257 GLU C N   1 
ATOM   8796  C CA  . GLU C 1 257 ? -0.673  -21.910 10.516  1.00 58.96  ? 257 GLU C CA  1 
ATOM   8797  C C   . GLU C 1 257 ? 0.077   -22.765 11.527  1.00 65.87  ? 257 GLU C C   1 
ATOM   8798  O O   . GLU C 1 257 ? -0.438  -23.778 11.992  1.00 69.13  ? 257 GLU C O   1 
ATOM   8799  C CB  . GLU C 1 257 ? -2.102  -21.651 10.989  1.00 66.77  ? 257 GLU C CB  1 
ATOM   8800  C CG  . GLU C 1 257 ? -2.648  -20.282 10.591  1.00 76.04  ? 257 GLU C CG  1 
ATOM   8801  C CD  . GLU C 1 257 ? -3.859  -19.838 11.405  1.00 85.69  ? 257 GLU C CD  1 
ATOM   8802  O OE1 . GLU C 1 257 ? -4.427  -20.673 12.177  1.00 88.46  ? 257 GLU C OE1 1 
ATOM   8803  O OE2 . GLU C 1 257 ? -4.229  -18.645 11.283  1.00 89.92  ? 257 GLU C OE2 1 
ATOM   8804  N N   . LEU C 1 258 ? 1.314   -22.373 11.821  1.00 67.93  ? 258 LEU C N   1 
ATOM   8805  C CA  . LEU C 1 258 ? 2.215   -23.218 12.571  1.00 73.29  ? 258 LEU C CA  1 
ATOM   8806  C C   . LEU C 1 258 ? 2.239   -22.791 14.036  1.00 79.35  ? 258 LEU C C   1 
ATOM   8807  O O   . LEU C 1 258 ? 2.448   -21.622 14.355  1.00 71.90  ? 258 LEU C O   1 
ATOM   8808  C CB  . LEU C 1 258 ? 3.587   -23.155 11.924  1.00 76.32  ? 258 LEU C CB  1 
ATOM   8809  C CG  . LEU C 1 258 ? 3.700   -23.884 10.585  1.00 75.66  ? 258 LEU C CG  1 
ATOM   8810  C CD1 . LEU C 1 258 ? 4.702   -23.216 9.696   1.00 80.77  ? 258 LEU C CD1 1 
ATOM   8811  C CD2 . LEU C 1 258 ? 4.059   -25.344 10.782  1.00 75.12  ? 258 LEU C CD2 1 
ATOM   8812  N N   . GLY C 1 259 ? 2.000   -23.764 14.919  1.00 100.48 ? 259 GLY C N   1 
ATOM   8813  C CA  . GLY C 1 259 ? 2.064   -23.541 16.348  1.00 111.52 ? 259 GLY C CA  1 
ATOM   8814  C C   . GLY C 1 259 ? 3.485   -23.220 16.774  1.00 113.22 ? 259 GLY C C   1 
ATOM   8815  O O   . GLY C 1 259 ? 4.438   -23.740 16.194  1.00 110.34 ? 259 GLY C O   1 
ATOM   8816  N N   . GLY C 1 260 ? 3.610   -22.325 17.757  1.00 114.70 ? 260 GLY C N   1 
ATOM   8817  C CA  . GLY C 1 260 ? 4.902   -21.814 18.170  1.00 108.28 ? 260 GLY C CA  1 
ATOM   8818  C C   . GLY C 1 260 ? 4.918   -21.492 19.657  1.00 97.81  ? 260 GLY C C   1 
ATOM   8819  O O   . GLY C 1 260 ? 3.879   -21.458 20.307  1.00 108.21 ? 260 GLY C O   1 
ATOM   8820  N N   . ASN C 1 261 ? 6.117   -21.319 20.185  1.00 82.89  ? 261 ASN C N   1 
ATOM   8821  C CA  . ASN C 1 261 ? 6.313   -20.744 21.491  1.00 79.98  ? 261 ASN C CA  1 
ATOM   8822  C C   . ASN C 1 261 ? 5.828   -19.296 21.469  1.00 75.26  ? 261 ASN C C   1 
ATOM   8823  O O   . ASN C 1 261 ? 6.454   -18.449 20.841  1.00 78.06  ? 261 ASN C O   1 
ATOM   8824  C CB  . ASN C 1 261 ? 7.776   -20.850 21.914  1.00 80.41  ? 261 ASN C CB  1 
ATOM   8825  C CG  . ASN C 1 261 ? 7.927   -20.842 23.413  1.00 82.19  ? 261 ASN C CG  1 
ATOM   8826  O OD1 . ASN C 1 261 ? 7.416   -19.934 24.074  1.00 83.23  ? 261 ASN C OD1 1 
ATOM   8827  N ND2 . ASN C 1 261 ? 8.598   -21.842 23.972  1.00 79.42  ? 261 ASN C ND2 1 
ATOM   8828  N N   . SER C 1 262 ? 4.694   -19.040 22.156  1.00 72.22  ? 262 SER C N   1 
ATOM   8829  C CA  . SER C 1 262 ? 4.058   -17.719 22.196  1.00 61.43  ? 262 SER C CA  1 
ATOM   8830  C C   . SER C 1 262 ? 4.403   -17.003 23.509  1.00 47.87  ? 262 SER C C   1 
ATOM   8831  O O   . SER C 1 262 ? 4.254   -17.574 24.592  1.00 44.89  ? 262 SER C O   1 
ATOM   8832  C CB  . SER C 1 262 ? 2.593   -17.837 22.032  1.00 62.32  ? 262 SER C CB  1 
ATOM   8833  O OG  . SER C 1 262 ? 2.252   -18.015 20.667  1.00 75.81  ? 262 SER C OG  1 
ATOM   8834  N N   . PRO C 1 263 ? 4.957   -15.775 23.449  1.00 37.99  ? 263 PRO C N   1 
ATOM   8835  C CA  . PRO C 1 263 ? 5.403   -15.082 24.650  1.00 40.48  ? 263 PRO C CA  1 
ATOM   8836  C C   . PRO C 1 263 ? 4.263   -14.353 25.363  1.00 40.51  ? 263 PRO C C   1 
ATOM   8837  O O   . PRO C 1 263 ? 3.427   -13.695 24.722  1.00 33.45  ? 263 PRO C O   1 
ATOM   8838  C CB  . PRO C 1 263 ? 6.477   -14.126 24.119  1.00 39.50  ? 263 PRO C CB  1 
ATOM   8839  C CG  . PRO C 1 263 ? 5.977   -13.752 22.733  1.00 38.20  ? 263 PRO C CG  1 
ATOM   8840  C CD  . PRO C 1 263 ? 5.256   -15.031 22.223  1.00 38.78  ? 263 PRO C CD  1 
ATOM   8841  N N   . PHE C 1 264 ? 4.194   -14.581 26.676  1.00 39.71  ? 264 PHE C N   1 
ATOM   8842  C CA  . PHE C 1 264 ? 3.273   -13.898 27.566  1.00 41.40  ? 264 PHE C CA  1 
ATOM   8843  C C   . PHE C 1 264 ? 4.082   -12.989 28.489  1.00 41.06  ? 264 PHE C C   1 
ATOM   8844  O O   . PHE C 1 264 ? 4.809   -13.471 29.350  1.00 43.73  ? 264 PHE C O   1 
ATOM   8845  C CB  . PHE C 1 264 ? 2.508   -14.994 28.321  1.00 38.11  ? 264 PHE C CB  1 
ATOM   8846  C CG  . PHE C 1 264 ? 1.365   -14.514 29.177  1.00 40.20  ? 264 PHE C CG  1 
ATOM   8847  C CD1 . PHE C 1 264 ? 1.597   -13.892 30.407  1.00 40.04  ? 264 PHE C CD1 1 
ATOM   8848  C CD2 . PHE C 1 264 ? 0.051   -14.744 28.794  1.00 42.64  ? 264 PHE C CD2 1 
ATOM   8849  C CE1 . PHE C 1 264 ? 0.541   -13.496 31.204  1.00 39.00  ? 264 PHE C CE1 1 
ATOM   8850  C CE2 . PHE C 1 264 ? -1.006  -14.334 29.601  1.00 43.11  ? 264 PHE C CE2 1 
ATOM   8851  C CZ  . PHE C 1 264 ? -0.759  -13.709 30.795  1.00 40.11  ? 264 PHE C CZ  1 
ATOM   8852  N N   . VAL C 1 265 ? 3.963   -11.684 28.289  1.00 41.57  ? 265 VAL C N   1 
ATOM   8853  C CA  . VAL C 1 265 ? 4.823   -10.718 28.957  1.00 40.71  ? 265 VAL C CA  1 
ATOM   8854  C C   . VAL C 1 265 ? 4.033   -9.976  30.048  1.00 40.99  ? 265 VAL C C   1 
ATOM   8855  O O   . VAL C 1 265 ? 2.920   -9.539  29.830  1.00 41.80  ? 265 VAL C O   1 
ATOM   8856  C CB  . VAL C 1 265 ? 5.417   -9.741  27.939  1.00 41.84  ? 265 VAL C CB  1 
ATOM   8857  C CG1 . VAL C 1 265 ? 6.363   -8.748  28.598  1.00 43.54  ? 265 VAL C CG1 1 
ATOM   8858  C CG2 . VAL C 1 265 ? 6.114   -10.478 26.799  1.00 44.26  ? 265 VAL C CG2 1 
ATOM   8859  N N   . VAL C 1 266 ? 4.649   -9.847  31.224  1.00 42.38  ? 266 VAL C N   1 
ATOM   8860  C CA  . VAL C 1 266 ? 4.087   -9.103  32.334  1.00 38.51  ? 266 VAL C CA  1 
ATOM   8861  C C   . VAL C 1 266 ? 5.067   -8.005  32.732  1.00 38.31  ? 266 VAL C C   1 
ATOM   8862  O O   . VAL C 1 266 ? 6.125   -8.296  33.284  1.00 40.14  ? 266 VAL C O   1 
ATOM   8863  C CB  . VAL C 1 266 ? 3.811   -10.028 33.523  1.00 39.35  ? 266 VAL C CB  1 
ATOM   8864  C CG1 . VAL C 1 266 ? 3.225   -9.251  34.713  1.00 42.49  ? 266 VAL C CG1 1 
ATOM   8865  C CG2 . VAL C 1 266 ? 2.917   -11.209 33.144  1.00 37.89  ? 266 VAL C CG2 1 
ATOM   8866  N N   . LEU C 1 267 ? 4.706   -6.749  32.453  1.00 37.13  ? 267 LEU C N   1 
ATOM   8867  C CA  . LEU C 1 267 ? 5.536   -5.606  32.835  1.00 40.91  ? 267 LEU C CA  1 
ATOM   8868  C C   . LEU C 1 267 ? 5.265   -5.208  34.304  1.00 41.73  ? 267 LEU C C   1 
ATOM   8869  O O   . LEU C 1 267 ? 4.307   -5.683  34.932  1.00 36.23  ? 267 LEU C O   1 
ATOM   8870  C CB  . LEU C 1 267 ? 5.301   -4.432  31.885  1.00 38.16  ? 267 LEU C CB  1 
ATOM   8871  C CG  . LEU C 1 267 ? 5.713   -4.666  30.438  1.00 45.22  ? 267 LEU C CG  1 
ATOM   8872  C CD1 . LEU C 1 267 ? 5.450   -3.449  29.562  1.00 45.03  ? 267 LEU C CD1 1 
ATOM   8873  C CD2 . LEU C 1 267 ? 7.163   -5.075  30.366  1.00 44.66  ? 267 LEU C CD2 1 
ATOM   8874  N N   . GLY C 1 268 ? 6.117   -4.303  34.825  1.00 40.33  ? 268 GLY C N   1 
ATOM   8875  C CA  . GLY C 1 268 ? 6.191   -4.026  36.253  1.00 43.31  ? 268 GLY C CA  1 
ATOM   8876  C C   . GLY C 1 268 ? 4.880   -3.479  36.822  1.00 46.01  ? 268 GLY C C   1 
ATOM   8877  O O   . GLY C 1 268 ? 4.545   -3.761  37.968  1.00 50.03  ? 268 GLY C O   1 
ATOM   8878  N N   . ASP C 1 269 ? 4.131   -2.723  36.001  1.00 47.84  ? 269 ASP C N   1 
ATOM   8879  C CA  . ASP C 1 269 ? 2.934   -2.029  36.459  1.00 42.06  ? 269 ASP C CA  1 
ATOM   8880  C C   . ASP C 1 269 ? 1.676   -2.872  36.213  1.00 41.17  ? 269 ASP C C   1 
ATOM   8881  O O   . ASP C 1 269 ? 0.583   -2.375  36.306  1.00 45.27  ? 269 ASP C O   1 
ATOM   8882  C CB  . ASP C 1 269 ? 2.806   -0.668  35.798  1.00 45.97  ? 269 ASP C CB  1 
ATOM   8883  C CG  . ASP C 1 269 ? 2.897   -0.686  34.290  1.00 53.69  ? 269 ASP C CG  1 
ATOM   8884  O OD1 . ASP C 1 269 ? 3.405   -1.685  33.757  1.00 60.19  ? 269 ASP C OD1 1 
ATOM   8885  O OD2 . ASP C 1 269 ? 2.441   0.286   33.665  1.00 64.70  ? 269 ASP C OD2 1 
ATOM   8886  N N   . ALA C 1 270 ? 1.827   -4.167  35.983  1.00 45.01  ? 270 ALA C N   1 
ATOM   8887  C CA  . ALA C 1 270 ? 0.676   -4.994  35.592  1.00 39.85  ? 270 ALA C CA  1 
ATOM   8888  C C   . ALA C 1 270 ? -0.303  -5.161  36.759  1.00 43.68  ? 270 ALA C C   1 
ATOM   8889  O O   . ALA C 1 270 ? 0.082   -5.107  37.928  1.00 42.41  ? 270 ALA C O   1 
ATOM   8890  C CB  . ALA C 1 270 ? 1.135   -6.333  35.077  1.00 36.80  ? 270 ALA C CB  1 
ATOM   8891  N N   . ASP C 1 271 ? -1.578  -5.375  36.407  1.00 41.45  ? 271 ASP C N   1 
ATOM   8892  C CA  . ASP C 1 271 ? -2.571  -5.868  37.329  1.00 41.95  ? 271 ASP C CA  1 
ATOM   8893  C C   . ASP C 1 271 ? -2.322  -7.355  37.595  1.00 44.85  ? 271 ASP C C   1 
ATOM   8894  O O   . ASP C 1 271 ? -2.662  -8.193  36.773  1.00 42.80  ? 271 ASP C O   1 
ATOM   8895  C CB  . ASP C 1 271 ? -3.947  -5.644  36.756  1.00 43.76  ? 271 ASP C CB  1 
ATOM   8896  C CG  . ASP C 1 271 ? -5.100  -6.156  37.589  1.00 49.37  ? 271 ASP C CG  1 
ATOM   8897  O OD1 . ASP C 1 271 ? -6.168  -5.542  37.499  1.00 56.75  ? 271 ASP C OD1 1 
ATOM   8898  O OD2 . ASP C 1 271 ? -4.914  -7.197  38.330  1.00 49.69  ? 271 ASP C OD2 1 
ATOM   8899  N N   . LEU C 1 272 ? -1.734  -7.671  38.758  1.00 47.39  ? 272 LEU C N   1 
ATOM   8900  C CA  . LEU C 1 272 ? -1.145  -8.988  38.985  1.00 46.35  ? 272 LEU C CA  1 
ATOM   8901  C C   . LEU C 1 272 ? -2.242  -10.059 38.967  1.00 42.79  ? 272 LEU C C   1 
ATOM   8902  O O   . LEU C 1 272 ? -2.089  -11.104 38.330  1.00 43.77  ? 272 LEU C O   1 
ATOM   8903  C CB  . LEU C 1 272 ? -0.365  -8.997  40.298  1.00 50.00  ? 272 LEU C CB  1 
ATOM   8904  C CG  . LEU C 1 272 ? 0.927   -9.825  40.332  1.00 53.57  ? 272 LEU C CG  1 
ATOM   8905  C CD1 . LEU C 1 272 ? 1.673   -9.820  39.008  1.00 51.79  ? 272 LEU C CD1 1 
ATOM   8906  C CD2 . LEU C 1 272 ? 1.836   -9.288  41.442  1.00 53.45  ? 272 LEU C CD2 1 
ATOM   8907  N N   . GLU C 1 273 ? -3.358  -9.789  39.628  1.00 39.42  ? 273 GLU C N   1 
ATOM   8908  C CA  . GLU C 1 273 ? -4.412  -10.784 39.717  1.00 46.40  ? 273 GLU C CA  1 
ATOM   8909  C C   . GLU C 1 273 ? -4.932  -11.132 38.308  1.00 45.99  ? 273 GLU C C   1 
ATOM   8910  O O   . GLU C 1 273 ? -5.147  -12.300 37.996  1.00 47.87  ? 273 GLU C O   1 
ATOM   8911  C CB  . GLU C 1 273 ? -5.520  -10.335 40.650  1.00 48.52  ? 273 GLU C CB  1 
ATOM   8912  C CG  . GLU C 1 273 ? -6.302  -11.500 41.252  1.00 58.84  ? 273 GLU C CG  1 
ATOM   8913  C CD  . GLU C 1 273 ? -7.709  -11.676 40.718  1.00 75.49  ? 273 GLU C CD  1 
ATOM   8914  O OE1 . GLU C 1 273 ? -8.522  -12.341 41.413  1.00 75.01  ? 273 GLU C OE1 1 
ATOM   8915  O OE2 . GLU C 1 273 ? -8.000  -11.151 39.607  1.00 93.48  ? 273 GLU C OE2 1 
ATOM   8916  N N   . GLN C 1 274 ? -5.112  -10.104 37.470  1.00 46.64  ? 274 GLN C N   1 
ATOM   8917  C CA  . GLN C 1 274 ? -5.516  -10.286 36.074  1.00 45.38  ? 274 GLN C CA  1 
ATOM   8918  C C   . GLN C 1 274 ? -4.484  -11.143 35.322  1.00 39.19  ? 274 GLN C C   1 
ATOM   8919  O O   . GLN C 1 274 ? -4.861  -12.095 34.616  1.00 32.44  ? 274 GLN C O   1 
ATOM   8920  C CB  . GLN C 1 274 ? -5.683  -8.936  35.360  1.00 46.41  ? 274 GLN C CB  1 
ATOM   8921  C CG  . GLN C 1 274 ? -7.081  -8.357  35.463  1.00 56.94  ? 274 GLN C CG  1 
ATOM   8922  C CD  . GLN C 1 274 ? -8.125  -9.211  34.795  1.00 59.66  ? 274 GLN C CD  1 
ATOM   8923  O OE1 . GLN C 1 274 ? -8.110  -9.411  33.576  1.00 58.28  ? 274 GLN C OE1 1 
ATOM   8924  N NE2 . GLN C 1 274 ? -9.044  -9.728  35.595  1.00 65.65  ? 274 GLN C NE2 1 
ATOM   8925  N N   . ALA C 1 275 ? -3.191  -10.760 35.439  1.00 30.14  ? 275 ALA C N   1 
ATOM   8926  C CA  . ALA C 1 275 ? -2.123  -11.427 34.732  1.00 33.71  ? 275 ALA C CA  1 
ATOM   8927  C C   . ALA C 1 275 ? -2.052  -12.898 35.144  1.00 39.66  ? 275 ALA C C   1 
ATOM   8928  O O   . ALA C 1 275 ? -1.895  -13.769 34.298  1.00 46.40  ? 275 ALA C O   1 
ATOM   8929  C CB  . ALA C 1 275 ? -0.818  -10.728 34.989  1.00 36.51  ? 275 ALA C CB  1 
ATOM   8930  N N   . VAL C 1 276 ? -2.171  -13.164 36.448  1.00 38.03  ? 276 VAL C N   1 
ATOM   8931  C CA  . VAL C 1 276 ? -2.044  -14.512 36.945  1.00 39.52  ? 276 VAL C CA  1 
ATOM   8932  C C   . VAL C 1 276 ? -3.226  -15.340 36.452  1.00 39.98  ? 276 VAL C C   1 
ATOM   8933  O O   . VAL C 1 276 ? -3.031  -16.440 35.906  1.00 41.77  ? 276 VAL C O   1 
ATOM   8934  C CB  . VAL C 1 276 ? -1.918  -14.557 38.477  1.00 42.71  ? 276 VAL C CB  1 
ATOM   8935  C CG1 . VAL C 1 276 ? -2.106  -15.973 39.024  1.00 43.73  ? 276 VAL C CG1 1 
ATOM   8936  C CG2 . VAL C 1 276 ? -0.578  -13.980 38.941  1.00 41.82  ? 276 VAL C CG2 1 
ATOM   8937  N N   . SER C 1 277 ? -4.444  -14.806 36.635  1.00 36.91  ? 277 SER C N   1 
ATOM   8938  C CA  . SER C 1 277 ? -5.660  -15.496 36.219  1.00 42.54  ? 277 SER C CA  1 
ATOM   8939  C C   . SER C 1 277 ? -5.611  -15.819 34.721  1.00 41.14  ? 277 SER C C   1 
ATOM   8940  O O   . SER C 1 277 ? -5.955  -16.924 34.312  1.00 38.33  ? 277 SER C O   1 
ATOM   8941  C CB  . SER C 1 277 ? -6.889  -14.699 36.554  1.00 43.06  ? 277 SER C CB  1 
ATOM   8942  O OG  . SER C 1 277 ? -6.983  -14.490 37.947  1.00 51.20  ? 277 SER C OG  1 
ATOM   8943  N N   . ALA C 1 278 ? -5.210  -14.831 33.913  1.00 39.00  ? 278 ALA C N   1 
ATOM   8944  C CA  . ALA C 1 278 ? -5.147  -15.002 32.466  1.00 42.67  ? 278 ALA C CA  1 
ATOM   8945  C C   . ALA C 1 278 ? -4.147  -16.110 32.097  1.00 41.06  ? 278 ALA C C   1 
ATOM   8946  O O   . ALA C 1 278 ? -4.454  -16.968 31.275  1.00 40.40  ? 278 ALA C O   1 
ATOM   8947  C CB  . ALA C 1 278 ? -4.791  -13.683 31.804  1.00 43.45  ? 278 ALA C CB  1 
ATOM   8948  N N   . ALA C 1 279 ? -2.971  -16.108 32.742  1.00 37.60  ? 279 ALA C N   1 
ATOM   8949  C CA  . ALA C 1 279 ? -1.933  -17.086 32.426  1.00 41.11  ? 279 ALA C CA  1 
ATOM   8950  C C   . ALA C 1 279 ? -2.414  -18.503 32.753  1.00 40.35  ? 279 ALA C C   1 
ATOM   8951  O O   . ALA C 1 279 ? -2.228  -19.408 31.952  1.00 46.20  ? 279 ALA C O   1 
ATOM   8952  C CB  . ALA C 1 279 ? -0.654  -16.753 33.143  1.00 39.08  ? 279 ALA C CB  1 
ATOM   8953  N N   . VAL C 1 280 ? -2.973  -18.676 33.948  1.00 37.67  ? 280 VAL C N   1 
ATOM   8954  C CA  . VAL C 1 280 ? -3.418  -20.032 34.373  1.00 36.74  ? 280 VAL C CA  1 
ATOM   8955  C C   . VAL C 1 280 ? -4.496  -20.501 33.387  1.00 41.43  ? 280 VAL C C   1 
ATOM   8956  O O   . VAL C 1 280 ? -4.340  -21.598 32.819  1.00 46.13  ? 280 VAL C O   1 
ATOM   8957  C CB  . VAL C 1 280 ? -3.927  -20.032 35.827  1.00 35.82  ? 280 VAL C CB  1 
ATOM   8958  C CG1 . VAL C 1 280 ? -4.603  -21.346 36.195  1.00 37.75  ? 280 VAL C CG1 1 
ATOM   8959  C CG2 . VAL C 1 280 ? -2.816  -19.710 36.816  1.00 37.12  ? 280 VAL C CG2 1 
ATOM   8960  N N   . PHE C 1 281 ? -5.532  -19.689 33.177  1.00 45.72  ? 281 PHE C N   1 
ATOM   8961  C CA  . PHE C 1 281 ? -6.652  -20.137 32.313  1.00 47.74  ? 281 PHE C CA  1 
ATOM   8962  C C   . PHE C 1 281 ? -6.199  -20.382 30.872  1.00 46.02  ? 281 PHE C C   1 
ATOM   8963  O O   . PHE C 1 281 ? -6.701  -21.337 30.252  1.00 43.97  ? 281 PHE C O   1 
ATOM   8964  C CB  . PHE C 1 281 ? -7.750  -19.071 32.362  1.00 52.23  ? 281 PHE C CB  1 
ATOM   8965  C CG  . PHE C 1 281 ? -8.978  -19.408 31.529  1.00 59.26  ? 281 PHE C CG  1 
ATOM   8966  C CD1 . PHE C 1 281 ? -9.842  -20.426 31.915  1.00 57.71  ? 281 PHE C CD1 1 
ATOM   8967  C CD2 . PHE C 1 281 ? -9.259  -18.716 30.358  1.00 59.32  ? 281 PHE C CD2 1 
ATOM   8968  C CE1 . PHE C 1 281 ? -10.956 -20.736 31.153  1.00 57.24  ? 281 PHE C CE1 1 
ATOM   8969  C CE2 . PHE C 1 281 ? -10.374 -19.032 29.600  1.00 53.17  ? 281 PHE C CE2 1 
ATOM   8970  C CZ  . PHE C 1 281 ? -11.219 -20.039 29.999  1.00 51.06  ? 281 PHE C CZ  1 
ATOM   8971  N N   . GLY C 1 282 ? -5.374  -19.508 30.295  1.00 44.74  ? 282 GLY C N   1 
ATOM   8972  C CA  . GLY C 1 282 ? -4.923  -19.832 28.931  1.00 46.82  ? 282 GLY C CA  1 
ATOM   8973  C C   . GLY C 1 282 ? -4.048  -21.068 28.831  1.00 45.38  ? 282 GLY C C   1 
ATOM   8974  O O   . GLY C 1 282 ? -4.324  -21.906 27.954  1.00 42.08  ? 282 GLY C O   1 
ATOM   8975  N N   . LYS C 1 283 ? -3.061  -21.207 29.724  1.00 48.68  ? 283 LYS C N   1 
ATOM   8976  C CA  . LYS C 1 283 ? -2.117  -22.356 29.660  1.00 49.36  ? 283 LYS C CA  1 
ATOM   8977  C C   . LYS C 1 283 ? -2.863  -23.662 29.938  1.00 49.48  ? 283 LYS C C   1 
ATOM   8978  O O   . LYS C 1 283 ? -2.617  -24.659 29.232  1.00 55.60  ? 283 LYS C O   1 
ATOM   8979  C CB  . LYS C 1 283 ? -0.944  -22.180 30.629  1.00 53.39  ? 283 LYS C CB  1 
ATOM   8980  C CG  . LYS C 1 283 ? -0.030  -23.386 30.754  1.00 58.54  ? 283 LYS C CG  1 
ATOM   8981  C CD  . LYS C 1 283 ? 1.153   -23.390 29.798  1.00 68.28  ? 283 LYS C CD  1 
ATOM   8982  C CE  . LYS C 1 283 ? 1.146   -24.569 28.883  1.00 65.70  ? 283 LYS C CE  1 
ATOM   8983  N NZ  . LYS C 1 283 ? 2.348   -24.619 28.047  1.00 66.92  ? 283 LYS C NZ  1 
ATOM   8984  N N   . PHE C 1 284 ? -3.754  -23.628 30.926  1.00 56.10  ? 284 PHE C N   1 
ATOM   8985  C CA  . PHE C 1 284 ? -4.502  -24.844 31.326  1.00 56.02  ? 284 PHE C CA  1 
ATOM   8986  C C   . PHE C 1 284 ? -5.982  -24.542 31.224  1.00 63.63  ? 284 PHE C C   1 
ATOM   8987  O O   . PHE C 1 284 ? -6.313  -23.474 31.753  1.00 76.95  ? 284 PHE C O   1 
ATOM   8988  C CB  . PHE C 1 284 ? -4.128  -25.238 32.757  1.00 49.98  ? 284 PHE C CB  1 
ATOM   8989  C CG  . PHE C 1 284 ? -2.675  -25.052 33.177  1.00 47.71  ? 284 PHE C CG  1 
ATOM   8990  C CD1 . PHE C 1 284 ? -1.732  -26.047 32.946  1.00 43.72  ? 284 PHE C CD1 1 
ATOM   8991  C CD2 . PHE C 1 284 ? -2.262  -23.898 33.832  1.00 46.14  ? 284 PHE C CD2 1 
ATOM   8992  C CE1 . PHE C 1 284 ? -0.414  -25.882 33.341  1.00 45.80  ? 284 PHE C CE1 1 
ATOM   8993  C CE2 . PHE C 1 284 ? -0.943  -23.737 34.223  1.00 51.81  ? 284 PHE C CE2 1 
ATOM   8994  C CZ  . PHE C 1 284 ? -0.023  -24.730 33.981  1.00 50.45  ? 284 PHE C CZ  1 
ATOM   8995  N N   . LEU C 1 285 ? -6.793  -25.413 30.617  1.00 68.65  ? 285 LEU C N   1 
ATOM   8996  C CA  . LEU C 1 285 ? -8.277  -25.287 30.479  1.00 69.69  ? 285 LEU C CA  1 
ATOM   8997  C C   . LEU C 1 285 ? -8.719  -24.614 29.166  1.00 85.82  ? 285 LEU C C   1 
ATOM   8998  O O   . LEU C 1 285 ? -9.908  -24.723 28.855  1.00 55.86  ? 285 LEU C O   1 
ATOM   8999  C CB  . LEU C 1 285 ? -8.929  -24.538 31.647  1.00 71.94  ? 285 LEU C CB  1 
ATOM   9000  C CG  . LEU C 1 285 ? -8.966  -25.241 33.006  1.00 70.98  ? 285 LEU C CG  1 
ATOM   9001  C CD1 . LEU C 1 285 ? -8.336  -24.354 34.066  1.00 71.37  ? 285 LEU C CD1 1 
ATOM   9002  C CD2 . LEU C 1 285 ? -10.406 -25.535 33.374  1.00 74.10  ? 285 LEU C CD2 1 
ATOM   9003  N N   . HIS C 1 286 ? -7.837  -24.004 28.377  1.00 124.28 ? 286 HIS C N   1 
ATOM   9004  C CA  . HIS C 1 286 ? -8.349  -23.470 27.084  1.00 121.22 ? 286 HIS C CA  1 
ATOM   9005  C C   . HIS C 1 286 ? -7.369  -23.713 25.936  1.00 109.23 ? 286 HIS C C   1 
ATOM   9006  O O   . HIS C 1 286 ? -7.650  -24.564 25.068  1.00 100.60 ? 286 HIS C O   1 
ATOM   9007  C CB  . HIS C 1 286 ? -8.646  -21.973 27.221  1.00 106.45 ? 286 HIS C CB  1 
ATOM   9008  C CG  . HIS C 1 286 ? -9.440  -21.392 26.098  1.00 108.96 ? 286 HIS C CG  1 
ATOM   9009  N ND1 . HIS C 1 286 ? -9.142  -21.586 24.767  1.00 122.91 ? 286 HIS C ND1 1 
ATOM   9010  C CD2 . HIS C 1 286 ? -10.524 -20.608 26.121  1.00 117.52 ? 286 HIS C CD2 1 
ATOM   9011  C CE1 . HIS C 1 286 ? -10.028 -20.946 24.021  1.00 122.59 ? 286 HIS C CE1 1 
ATOM   9012  N NE2 . HIS C 1 286 ? -10.875 -20.342 24.823  1.00 118.90 ? 286 HIS C NE2 1 
ATOM   9013  N N   . GLN C 1 287 ? -6.240  -23.003 25.958  1.00 95.50  ? 287 GLN C N   1 
ATOM   9014  C CA  . GLN C 1 287 ? -5.211  -23.078 24.883  1.00 107.62 ? 287 GLN C CA  1 
ATOM   9015  C C   . GLN C 1 287 ? -5.769  -23.333 23.471  1.00 144.55 ? 287 GLN C C   1 
ATOM   9016  O O   . GLN C 1 287 ? -6.497  -22.455 22.962  1.00 173.90 ? 287 GLN C O   1 
ATOM   9017  C CB  . GLN C 1 287 ? -4.175  -24.138 25.264  1.00 102.12 ? 287 GLN C CB  1 
ATOM   9018  C CG  . GLN C 1 287 ? -2.750  -23.782 24.849  1.00 97.97  ? 287 GLN C CG  1 
ATOM   9019  C CD  . GLN C 1 287 ? -2.028  -22.899 25.843  1.00 84.27  ? 287 GLN C CD  1 
ATOM   9020  O OE1 . GLN C 1 287 ? -1.134  -23.346 26.570  1.00 69.65  ? 287 GLN C OE1 1 
ATOM   9021  N NE2 . GLN C 1 287 ? -2.399  -21.628 25.878  1.00 91.85  ? 287 GLN C NE2 1 
ATOM   9022  N N   . GLY C 1 288 ? -5.442  -24.474 22.870  1.00 160.10 ? 288 GLY C N   1 
ATOM   9023  C CA  . GLY C 1 288 ? -5.753  -24.832 21.474  1.00 151.75 ? 288 GLY C CA  1 
ATOM   9024  C C   . GLY C 1 288 ? -5.418  -23.690 20.534  1.00 131.38 ? 288 GLY C C   1 
ATOM   9025  O O   . GLY C 1 288 ? -4.221  -23.556 20.204  1.00 100.25 ? 288 GLY C O   1 
ATOM   9026  N N   . ILE C 1 294 ? 0.778   -21.110 24.997  1.00 105.25 ? 294 ILE C N   1 
ATOM   9027  C CA  . ILE C 1 294 ? 1.514   -20.115 25.768  1.00 87.93  ? 294 ILE C CA  1 
ATOM   9028  C C   . ILE C 1 294 ? 2.582   -20.828 26.576  1.00 85.06  ? 294 ILE C C   1 
ATOM   9029  O O   . ILE C 1 294 ? 2.276   -21.582 27.489  1.00 81.91  ? 294 ILE C O   1 
ATOM   9030  C CB  . ILE C 1 294 ? 0.579   -19.289 26.667  1.00 86.35  ? 294 ILE C CB  1 
ATOM   9031  C CG1 . ILE C 1 294 ? -0.550  -18.646 25.859  1.00 87.45  ? 294 ILE C CG1 1 
ATOM   9032  C CG2 . ILE C 1 294 ? 1.372   -18.252 27.460  1.00 85.01  ? 294 ILE C CG2 1 
ATOM   9033  C CD1 . ILE C 1 294 ? -0.129  -18.172 24.472  1.00 78.47  ? 294 ILE C CD1 1 
ATOM   9034  N N   . ASN C 1 295 ? 3.838   -20.593 26.220  1.00 80.59  ? 295 ASN C N   1 
ATOM   9035  C CA  . ASN C 1 295 ? 4.893   -21.513 26.588  1.00 80.74  ? 295 ASN C CA  1 
ATOM   9036  C C   . ASN C 1 295 ? 5.950   -20.834 27.450  1.00 68.41  ? 295 ASN C C   1 
ATOM   9037  O O   . ASN C 1 295 ? 6.657   -21.499 28.204  1.00 70.33  ? 295 ASN C O   1 
ATOM   9038  C CB  . ASN C 1 295 ? 5.556   -22.103 25.369  1.00 99.59  ? 295 ASN C CB  1 
ATOM   9039  C CG  . ASN C 1 295 ? 6.248   -23.379 25.715  1.00 120.03 ? 295 ASN C CG  1 
ATOM   9040  O OD1 . ASN C 1 295 ? 7.456   -23.380 25.982  1.00 125.96 ? 295 ASN C OD1 1 
ATOM   9041  N ND2 . ASN C 1 295 ? 5.478   -24.449 25.850  1.00 132.56 ? 295 ASN C ND2 1 
ATOM   9042  N N   . ARG C 1 296 ? 6.125   -19.519 27.273  1.00 59.69  ? 296 ARG C N   1 
ATOM   9043  C CA  . ARG C 1 296 ? 7.150   -18.766 27.958  1.00 51.30  ? 296 ARG C CA  1 
ATOM   9044  C C   . ARG C 1 296 ? 6.495   -17.532 28.570  1.00 50.23  ? 296 ARG C C   1 
ATOM   9045  O O   . ARG C 1 296 ? 5.756   -16.814 27.895  1.00 47.14  ? 296 ARG C O   1 
ATOM   9046  C CB  . ARG C 1 296 ? 8.281   -18.371 27.007  1.00 50.00  ? 296 ARG C CB  1 
ATOM   9047  N N   . ILE C 1 297 ? 6.699   -17.359 29.872  1.00 47.53  ? 297 ILE C N   1 
ATOM   9048  C CA  . ILE C 1 297 ? 6.172   -16.218 30.603  1.00 41.01  ? 297 ILE C CA  1 
ATOM   9049  C C   . ILE C 1 297 ? 7.338   -15.352 31.057  1.00 37.27  ? 297 ILE C C   1 
ATOM   9050  O O   . ILE C 1 297 ? 8.220   -15.827 31.745  1.00 45.49  ? 297 ILE C O   1 
ATOM   9051  C CB  . ILE C 1 297 ? 5.323   -16.682 31.788  1.00 40.61  ? 297 ILE C CB  1 
ATOM   9052  C CG1 . ILE C 1 297 ? 4.173   -17.541 31.335  1.00 37.18  ? 297 ILE C CG1 1 
ATOM   9053  C CG2 . ILE C 1 297 ? 4.849   -15.491 32.617  1.00 41.67  ? 297 ILE C CG2 1 
ATOM   9054  C CD1 . ILE C 1 297 ? 3.423   -18.213 32.458  1.00 38.77  ? 297 ILE C CD1 1 
ATOM   9055  N N   . ILE C 1 298 ? 7.347   -14.102 30.598  1.00 36.37  ? 298 ILE C N   1 
ATOM   9056  C CA  . ILE C 1 298 ? 8.440   -13.175 30.832  1.00 39.31  ? 298 ILE C CA  1 
ATOM   9057  C C   . ILE C 1 298 ? 7.938   -12.058 31.740  1.00 42.01  ? 298 ILE C C   1 
ATOM   9058  O O   . ILE C 1 298 ? 7.014   -11.334 31.376  1.00 55.06  ? 298 ILE C O   1 
ATOM   9059  C CB  . ILE C 1 298 ? 8.961   -12.623 29.497  1.00 38.29  ? 298 ILE C CB  1 
ATOM   9060  C CG1 . ILE C 1 298 ? 9.480   -13.739 28.619  1.00 39.37  ? 298 ILE C CG1 1 
ATOM   9061  C CG2 . ILE C 1 298 ? 10.018  -11.518 29.710  1.00 41.06  ? 298 ILE C CG2 1 
ATOM   9062  C CD1 . ILE C 1 298 ? 9.222   -13.532 27.138  1.00 40.13  ? 298 ILE C CD1 1 
ATOM   9063  N N   . VAL C 1 299 ? 8.558   -11.922 32.912  1.00 39.67  ? 299 VAL C N   1 
ATOM   9064  C CA  . VAL C 1 299 ? 8.118   -10.948 33.905  1.00 44.00  ? 299 VAL C CA  1 
ATOM   9065  C C   . VAL C 1 299 ? 9.293   -10.051 34.286  1.00 43.67  ? 299 VAL C C   1 
ATOM   9066  O O   . VAL C 1 299 ? 10.390  -10.557 34.567  1.00 42.07  ? 299 VAL C O   1 
ATOM   9067  C CB  . VAL C 1 299 ? 7.540   -11.639 35.147  1.00 42.89  ? 299 VAL C CB  1 
ATOM   9068  C CG1 . VAL C 1 299 ? 6.668   -10.683 35.959  1.00 47.77  ? 299 VAL C CG1 1 
ATOM   9069  C CG2 . VAL C 1 299 ? 6.770   -12.917 34.791  1.00 39.08  ? 299 VAL C CG2 1 
ATOM   9070  N N   . GLU C 1 300 ? 9.042   -8.724  34.326  1.00 40.93  ? 300 GLU C N   1 
ATOM   9071  C CA  . GLU C 1 300 ? 10.007  -7.765  34.861  1.00 47.23  ? 300 GLU C CA  1 
ATOM   9072  C C   . GLU C 1 300 ? 10.400  -8.161  36.283  1.00 47.60  ? 300 GLU C C   1 
ATOM   9073  O O   . GLU C 1 300 ? 9.544   -8.610  37.087  1.00 45.30  ? 300 GLU C O   1 
ATOM   9074  C CB  . GLU C 1 300 ? 9.469   -6.342  34.959  1.00 50.75  ? 300 GLU C CB  1 
ATOM   9075  C CG  . GLU C 1 300 ? 9.490   -5.578  33.656  1.00 51.96  ? 300 GLU C CG  1 
ATOM   9076  C CD  . GLU C 1 300 ? 9.586   -4.091  33.887  1.00 58.05  ? 300 GLU C CD  1 
ATOM   9077  O OE1 . GLU C 1 300 ? 10.544  -3.707  34.583  1.00 57.40  ? 300 GLU C OE1 1 
ATOM   9078  O OE2 . GLU C 1 300 ? 8.739   -3.311  33.357  1.00 60.52  ? 300 GLU C OE2 1 
ATOM   9079  N N   . ASP C 1 301 ? 11.680  -7.904  36.606  1.00 49.40  ? 301 ASP C N   1 
ATOM   9080  C CA  . ASP C 1 301 ? 12.320  -8.432  37.806  1.00 53.81  ? 301 ASP C CA  1 
ATOM   9081  C C   . ASP C 1 301 ? 11.534  -8.003  39.046  1.00 52.42  ? 301 ASP C C   1 
ATOM   9082  O O   . ASP C 1 301 ? 11.403  -8.779  39.984  1.00 53.42  ? 301 ASP C O   1 
ATOM   9083  C CB  . ASP C 1 301 ? 13.789  -8.013  37.879  1.00 56.86  ? 301 ASP C CB  1 
ATOM   9084  C CG  . ASP C 1 301 ? 14.492  -8.325  39.194  1.00 58.36  ? 301 ASP C CG  1 
ATOM   9085  O OD1 . ASP C 1 301 ? 14.946  -9.466  39.360  1.00 52.22  ? 301 ASP C OD1 1 
ATOM   9086  O OD2 . ASP C 1 301 ? 14.505  -7.435  40.073  1.00 68.09  ? 301 ASP C OD2 1 
ATOM   9087  N N   . SER C 1 302 ? 11.001  -6.765  39.030  1.00 50.82  ? 302 SER C N   1 
ATOM   9088  C CA  . SER C 1 302 ? 10.280  -6.216  40.179  1.00 48.64  ? 302 SER C CA  1 
ATOM   9089  C C   . SER C 1 302 ? 9.060   -7.080  40.534  1.00 49.87  ? 302 SER C C   1 
ATOM   9090  O O   . SER C 1 302 ? 8.809   -7.322  41.702  1.00 56.64  ? 302 SER C O   1 
ATOM   9091  C CB  . SER C 1 302 ? 9.889   -4.795  39.941  1.00 45.87  ? 302 SER C CB  1 
ATOM   9092  O OG  . SER C 1 302 ? 9.210   -4.678  38.713  1.00 52.77  ? 302 SER C OG  1 
ATOM   9093  N N   . LEU C 1 303 ? 8.312   -7.566  39.525  1.00 49.17  ? 303 LEU C N   1 
ATOM   9094  C CA  . LEU C 1 303 ? 7.079   -8.331  39.798  1.00 42.77  ? 303 LEU C CA  1 
ATOM   9095  C C   . LEU C 1 303 ? 7.331   -9.836  39.750  1.00 39.40  ? 303 LEU C C   1 
ATOM   9096  O O   . LEU C 1 303 ? 6.393   -10.625 40.027  1.00 42.38  ? 303 LEU C O   1 
ATOM   9097  C CB  . LEU C 1 303 ? 5.964   -7.964  38.828  1.00 41.09  ? 303 LEU C CB  1 
ATOM   9098  C CG  . LEU C 1 303 ? 5.057   -6.812  39.241  1.00 50.98  ? 303 LEU C CG  1 
ATOM   9099  C CD1 . LEU C 1 303 ? 3.765   -6.870  38.417  1.00 47.29  ? 303 LEU C CD1 1 
ATOM   9100  C CD2 . LEU C 1 303 ? 4.748   -6.802  40.754  1.00 52.88  ? 303 LEU C CD2 1 
ATOM   9101  N N   . TYR C 1 304 ? 8.552   -10.245 39.354  1.00 34.76  ? 304 TYR C N   1 
ATOM   9102  C CA  . TYR C 1 304 ? 8.833   -11.656 39.053  1.00 38.61  ? 304 TYR C CA  1 
ATOM   9103  C C   . TYR C 1 304 ? 8.450   -12.555 40.254  1.00 37.38  ? 304 TYR C C   1 
ATOM   9104  O O   . TYR C 1 304 ? 7.625   -13.494 40.120  1.00 45.69  ? 304 TYR C O   1 
ATOM   9105  C CB  . TYR C 1 304 ? 10.294  -11.882 38.650  1.00 39.60  ? 304 TYR C CB  1 
ATOM   9106  C CG  . TYR C 1 304 ? 10.599  -13.358 38.391  1.00 47.26  ? 304 TYR C CG  1 
ATOM   9107  C CD1 . TYR C 1 304 ? 10.471  -13.909 37.126  1.00 48.87  ? 304 TYR C CD1 1 
ATOM   9108  C CD2 . TYR C 1 304 ? 10.964  -14.212 39.429  1.00 50.36  ? 304 TYR C CD2 1 
ATOM   9109  C CE1 . TYR C 1 304 ? 10.718  -15.258 36.892  1.00 45.23  ? 304 TYR C CE1 1 
ATOM   9110  C CE2 . TYR C 1 304 ? 11.179  -15.565 39.219  1.00 47.57  ? 304 TYR C CE2 1 
ATOM   9111  C CZ  . TYR C 1 304 ? 11.063  -16.089 37.946  1.00 46.32  ? 304 TYR C CZ  1 
ATOM   9112  O OH  . TYR C 1 304 ? 11.285  -17.420 37.760  1.00 45.79  ? 304 TYR C OH  1 
ATOM   9113  N N   . ASP C 1 305 ? 9.057   -12.304 41.411  1.00 37.25  ? 305 ASP C N   1 
ATOM   9114  C CA  . ASP C 1 305 ? 8.896   -13.206 42.559  1.00 42.53  ? 305 ASP C CA  1 
ATOM   9115  C C   . ASP C 1 305 ? 7.443   -13.234 43.000  1.00 41.43  ? 305 ASP C C   1 
ATOM   9116  O O   . ASP C 1 305 ? 6.912   -14.294 43.370  1.00 46.36  ? 305 ASP C O   1 
ATOM   9117  C CB  . ASP C 1 305 ? 9.864   -12.869 43.681  1.00 44.56  ? 305 ASP C CB  1 
ATOM   9118  C CG  . ASP C 1 305 ? 11.326  -13.119 43.345  1.00 47.50  ? 305 ASP C CG  1 
ATOM   9119  O OD1 . ASP C 1 305 ? 11.676  -14.298 43.083  1.00 46.01  ? 305 ASP C OD1 1 
ATOM   9120  O OD2 . ASP C 1 305 ? 12.070  -12.141 43.233  1.00 56.23  ? 305 ASP C OD2 1 
ATOM   9121  N N   . ALA C 1 306 ? 6.785   -12.082 42.912  1.00 45.92  ? 306 ALA C N   1 
ATOM   9122  C CA  . ALA C 1 306 ? 5.377   -11.976 43.280  1.00 46.38  ? 306 ALA C CA  1 
ATOM   9123  C C   . ALA C 1 306 ? 4.508   -12.805 42.315  1.00 42.39  ? 306 ALA C C   1 
ATOM   9124  O O   . ALA C 1 306 ? 3.582   -13.512 42.751  1.00 42.02  ? 306 ALA C O   1 
ATOM   9125  C CB  . ALA C 1 306 ? 4.973   -10.517 43.306  1.00 46.45  ? 306 ALA C CB  1 
ATOM   9126  N N   . PHE C 1 307 ? 4.820   -12.724 41.006  1.00 40.81  ? 307 PHE C N   1 
ATOM   9127  C CA  . PHE C 1 307 ? 4.057   -13.450 39.990  1.00 40.68  ? 307 PHE C CA  1 
ATOM   9128  C C   . PHE C 1 307 ? 4.216   -14.950 40.207  1.00 38.19  ? 307 PHE C C   1 
ATOM   9129  O O   . PHE C 1 307 ? 3.232   -15.704 40.179  1.00 34.91  ? 307 PHE C O   1 
ATOM   9130  C CB  . PHE C 1 307 ? 4.507   -13.094 38.569  1.00 44.40  ? 307 PHE C CB  1 
ATOM   9131  C CG  . PHE C 1 307 ? 3.655   -13.749 37.494  1.00 42.57  ? 307 PHE C CG  1 
ATOM   9132  C CD1 . PHE C 1 307 ? 3.905   -15.056 37.079  1.00 44.88  ? 307 PHE C CD1 1 
ATOM   9133  C CD2 . PHE C 1 307 ? 2.596   -13.068 36.914  1.00 43.77  ? 307 PHE C CD2 1 
ATOM   9134  C CE1 . PHE C 1 307 ? 3.107   -15.662 36.114  1.00 44.48  ? 307 PHE C CE1 1 
ATOM   9135  C CE2 . PHE C 1 307 ? 1.809   -13.670 35.949  1.00 49.46  ? 307 PHE C CE2 1 
ATOM   9136  C CZ  . PHE C 1 307 ? 2.068   -14.974 35.552  1.00 47.61  ? 307 PHE C CZ  1 
ATOM   9137  N N   . ALA C 1 308 ? 5.467   -15.383 40.412  1.00 39.40  ? 308 ALA C N   1 
ATOM   9138  C CA  . ALA C 1 308 ? 5.768   -16.807 40.527  1.00 42.96  ? 308 ALA C CA  1 
ATOM   9139  C C   . ALA C 1 308 ? 4.968   -17.425 41.668  1.00 43.64  ? 308 ALA C C   1 
ATOM   9140  O O   . ALA C 1 308 ? 4.378   -18.508 41.517  1.00 46.43  ? 308 ALA C O   1 
ATOM   9141  C CB  . ALA C 1 308 ? 7.259   -17.006 40.715  1.00 45.39  ? 308 ALA C CB  1 
ATOM   9142  N N   . ALA C 1 309 ? 4.942   -16.732 42.811  1.00 43.21  ? 309 ALA C N   1 
ATOM   9143  C CA  . ALA C 1 309 ? 4.288   -17.258 44.004  1.00 47.41  ? 309 ALA C CA  1 
ATOM   9144  C C   . ALA C 1 309 ? 2.792   -17.482 43.743  1.00 42.98  ? 309 ALA C C   1 
ATOM   9145  O O   . ALA C 1 309 ? 2.274   -18.575 43.993  1.00 39.23  ? 309 ALA C O   1 
ATOM   9146  C CB  . ALA C 1 309 ? 4.520   -16.323 45.174  1.00 54.41  ? 309 ALA C CB  1 
ATOM   9147  N N   . ARG C 1 310 ? 2.103   -16.449 43.227  1.00 41.81  ? 310 ARG C N   1 
ATOM   9148  C CA  . ARG C 1 310 ? 0.655   -16.533 43.034  1.00 43.44  ? 310 ARG C CA  1 
ATOM   9149  C C   . ARG C 1 310 ? 0.348   -17.553 41.942  1.00 40.57  ? 310 ARG C C   1 
ATOM   9150  O O   . ARG C 1 310 ? -0.575  -18.358 42.090  1.00 38.22  ? 310 ARG C O   1 
ATOM   9151  C CB  . ARG C 1 310 ? 0.058   -15.166 42.704  1.00 51.54  ? 310 ARG C CB  1 
ATOM   9152  C CG  . ARG C 1 310 ? 0.256   -14.110 43.791  1.00 52.55  ? 310 ARG C CG  1 
ATOM   9153  C CD  . ARG C 1 310 ? 0.349   -12.698 43.217  1.00 60.53  ? 310 ARG C CD  1 
ATOM   9154  N NE  . ARG C 1 310 ? -0.977  -12.168 42.846  1.00 66.22  ? 310 ARG C NE  1 
ATOM   9155  C CZ  . ARG C 1 310 ? -1.502  -11.027 43.288  1.00 48.85  ? 310 ARG C CZ  1 
ATOM   9156  N NH1 . ARG C 1 310 ? -0.796  -10.225 44.050  1.00 47.47  ? 310 ARG C NH1 1 
ATOM   9157  N NH2 . ARG C 1 310 ? -2.713  -10.684 42.927  1.00 43.03  ? 310 ARG C NH2 1 
ATOM   9158  N N   . PHE C 1 311 ? 1.179   -17.569 40.875  1.00 43.72  ? 311 PHE C N   1 
ATOM   9159  C CA  . PHE C 1 311 ? 0.984   -18.502 39.749  1.00 44.46  ? 311 PHE C CA  1 
ATOM   9160  C C   . PHE C 1 311 ? 1.076   -19.956 40.247  1.00 43.05  ? 311 PHE C C   1 
ATOM   9161  O O   . PHE C 1 311 ? 0.168   -20.761 40.033  1.00 39.56  ? 311 PHE C O   1 
ATOM   9162  C CB  . PHE C 1 311 ? 2.001   -18.223 38.646  1.00 49.33  ? 311 PHE C CB  1 
ATOM   9163  C CG  . PHE C 1 311 ? 1.805   -19.054 37.390  1.00 55.31  ? 311 PHE C CG  1 
ATOM   9164  C CD1 . PHE C 1 311 ? 0.789   -18.763 36.501  1.00 55.86  ? 311 PHE C CD1 1 
ATOM   9165  C CD2 . PHE C 1 311 ? 2.650   -20.121 37.094  1.00 58.76  ? 311 PHE C CD2 1 
ATOM   9166  C CE1 . PHE C 1 311 ? 0.617   -19.514 35.355  1.00 59.99  ? 311 PHE C CE1 1 
ATOM   9167  C CE2 . PHE C 1 311 ? 2.467   -20.871 35.948  1.00 57.24  ? 311 PHE C CE2 1 
ATOM   9168  C CZ  . PHE C 1 311 ? 1.453   -20.565 35.081  1.00 59.30  ? 311 PHE C CZ  1 
ATOM   9169  N N   . VAL C 1 312 ? 2.147   -20.270 40.959  1.00 44.31  ? 312 VAL C N   1 
ATOM   9170  C CA  . VAL C 1 312 ? 2.339   -21.618 41.472  1.00 47.03  ? 312 VAL C CA  1 
ATOM   9171  C C   . VAL C 1 312 ? 1.180   -21.976 42.412  1.00 45.52  ? 312 VAL C C   1 
ATOM   9172  O O   . VAL C 1 312 ? 0.705   -23.127 42.429  1.00 43.03  ? 312 VAL C O   1 
ATOM   9173  C CB  . VAL C 1 312 ? 3.700   -21.755 42.178  1.00 57.59  ? 312 VAL C CB  1 
ATOM   9174  C CG1 . VAL C 1 312 ? 3.767   -23.022 43.030  1.00 62.87  ? 312 VAL C CG1 1 
ATOM   9175  C CG2 . VAL C 1 312 ? 4.872   -21.694 41.189  1.00 53.57  ? 312 VAL C CG2 1 
ATOM   9176  N N   . GLU C 1 313 ? 0.731   -20.995 43.200  1.00 42.00  ? 313 GLU C N   1 
ATOM   9177  C CA  . GLU C 1 313 ? -0.289  -21.240 44.200  1.00 43.07  ? 313 GLU C CA  1 
ATOM   9178  C C   . GLU C 1 313 ? -1.581  -21.675 43.527  1.00 44.42  ? 313 GLU C C   1 
ATOM   9179  O O   . GLU C 1 313 ? -2.191  -22.630 43.967  1.00 53.23  ? 313 GLU C O   1 
ATOM   9180  C CB  . GLU C 1 313 ? -0.482  -20.016 45.099  1.00 52.61  ? 313 GLU C CB  1 
ATOM   9181  C CG  . GLU C 1 313 ? -1.629  -20.163 46.106  1.00 60.88  ? 313 GLU C CG  1 
ATOM   9182  C CD  . GLU C 1 313 ? -1.429  -21.229 47.184  1.00 66.54  ? 313 GLU C CD  1 
ATOM   9183  O OE1 . GLU C 1 313 ? -0.378  -21.201 47.862  1.00 69.81  ? 313 GLU C OE1 1 
ATOM   9184  O OE2 . GLU C 1 313 ? -2.331  -22.078 47.351  1.00 67.96  ? 313 GLU C OE2 1 
ATOM   9185  N N   . ARG C 1 314 ? -1.999  -20.963 42.454  1.00 49.19  ? 314 ARG C N   1 
ATOM   9186  C CA  . ARG C 1 314 ? -3.271  -21.277 41.779  1.00 52.48  ? 314 ARG C CA  1 
ATOM   9187  C C   . ARG C 1 314 ? -3.148  -22.625 41.077  1.00 46.56  ? 314 ARG C C   1 
ATOM   9188  O O   . ARG C 1 314 ? -4.087  -23.410 41.079  1.00 43.55  ? 314 ARG C O   1 
ATOM   9189  C CB  . ARG C 1 314 ? -3.710  -20.235 40.727  1.00 63.09  ? 314 ARG C CB  1 
ATOM   9190  C CG  . ARG C 1 314 ? -3.388  -18.785 41.072  1.00 80.50  ? 314 ARG C CG  1 
ATOM   9191  C CD  . ARG C 1 314 ? -4.487  -18.114 41.883  1.00 80.49  ? 314 ARG C CD  1 
ATOM   9192  N NE  . ARG C 1 314 ? -5.736  -18.059 41.117  1.00 79.91  ? 314 ARG C NE  1 
ATOM   9193  C CZ  . ARG C 1 314 ? -6.047  -17.138 40.197  1.00 81.80  ? 314 ARG C CZ  1 
ATOM   9194  N NH1 . ARG C 1 314 ? -5.280  -16.049 40.010  1.00 76.27  ? 314 ARG C NH1 1 
ATOM   9195  N NH2 . ARG C 1 314 ? -7.155  -17.283 39.496  1.00 83.55  ? 314 ARG C NH2 1 
ATOM   9196  N N   . VAL C 1 315 ? -1.983  -22.862 40.453  1.00 46.72  ? 315 VAL C N   1 
ATOM   9197  C CA  . VAL C 1 315 ? -1.770  -24.049 39.631  1.00 50.65  ? 315 VAL C CA  1 
ATOM   9198  C C   . VAL C 1 315 ? -1.902  -25.306 40.502  1.00 51.05  ? 315 VAL C C   1 
ATOM   9199  O O   . VAL C 1 315 ? -2.521  -26.286 40.073  1.00 44.58  ? 315 VAL C O   1 
ATOM   9200  C CB  . VAL C 1 315 ? -0.410  -24.005 38.896  1.00 51.15  ? 315 VAL C CB  1 
ATOM   9201  C CG1 . VAL C 1 315 ? 0.015   -25.374 38.392  1.00 51.48  ? 315 VAL C CG1 1 
ATOM   9202  C CG2 . VAL C 1 315 ? -0.425  -23.007 37.744  1.00 49.06  ? 315 VAL C CG2 1 
ATOM   9203  N N   . LYS C 1 316 ? -1.347  -25.255 41.739  1.00 53.01  ? 316 LYS C N   1 
ATOM   9204  C CA  . LYS C 1 316 ? -1.436  -26.374 42.680  1.00 50.16  ? 316 LYS C CA  1 
ATOM   9205  C C   . LYS C 1 316 ? -2.889  -26.710 42.944  1.00 47.56  ? 316 LYS C C   1 
ATOM   9206  O O   . LYS C 1 316 ? -3.219  -27.856 43.168  1.00 55.55  ? 316 LYS C O   1 
ATOM   9207  C CB  . LYS C 1 316 ? -0.779  -26.048 44.022  1.00 58.72  ? 316 LYS C CB  1 
ATOM   9208  C CG  . LYS C 1 316 ? 0.731   -25.916 44.014  1.00 65.94  ? 316 LYS C CG  1 
ATOM   9209  C CD  . LYS C 1 316 ? 1.271   -25.340 45.329  1.00 69.57  ? 316 LYS C CD  1 
ATOM   9210  C CE  . LYS C 1 316 ? 2.636   -25.874 45.690  1.00 72.38  ? 316 LYS C CE  1 
ATOM   9211  N NZ  . LYS C 1 316 ? 3.149   -25.304 46.938  1.00 70.15  ? 316 LYS C NZ  1 
ATOM   9212  N N   . GLY C 1 317 ? -3.753  -25.689 42.921  1.00 45.96  ? 317 GLY C N   1 
ATOM   9213  C CA  . GLY C 1 317 ? -5.184  -25.876 43.152  1.00 46.07  ? 317 GLY C CA  1 
ATOM   9214  C C   . GLY C 1 317 ? -5.900  -26.537 41.963  1.00 45.34  ? 317 GLY C C   1 
ATOM   9215  O O   . GLY C 1 317 ? -7.047  -26.991 42.096  1.00 44.43  ? 317 GLY C O   1 
ATOM   9216  N N   . LEU C 1 318 ? -5.263  -26.531 40.783  1.00 46.24  ? 318 LEU C N   1 
ATOM   9217  C CA  . LEU C 1 318 ? -5.930  -27.012 39.585  1.00 47.90  ? 318 LEU C CA  1 
ATOM   9218  C C   . LEU C 1 318 ? -6.194  -28.503 39.745  1.00 50.76  ? 318 LEU C C   1 
ATOM   9219  O O   . LEU C 1 318 ? -5.355  -29.257 40.234  1.00 43.74  ? 318 LEU C O   1 
ATOM   9220  C CB  . LEU C 1 318 ? -5.110  -26.709 38.333  1.00 50.45  ? 318 LEU C CB  1 
ATOM   9221  C CG  . LEU C 1 318 ? -5.003  -25.231 37.949  1.00 52.21  ? 318 LEU C CG  1 
ATOM   9222  C CD1 . LEU C 1 318 ? -4.022  -25.044 36.808  1.00 49.91  ? 318 LEU C CD1 1 
ATOM   9223  C CD2 . LEU C 1 318 ? -6.363  -24.662 37.580  1.00 54.88  ? 318 LEU C CD2 1 
ATOM   9224  N N   . ARG C 1 319 ? -7.348  -28.923 39.321  1.00 54.93  ? 319 ARG C N   1 
ATOM   9225  C CA  . ARG C 1 319 ? -7.820  -30.215 39.692  1.00 56.84  ? 319 ARG C CA  1 
ATOM   9226  C C   . ARG C 1 319 ? -7.704  -31.167 38.497  1.00 59.71  ? 319 ARG C C   1 
ATOM   9227  O O   . ARG C 1 319 ? -8.263  -30.917 37.410  1.00 53.15  ? 319 ARG C O   1 
ATOM   9228  C CB  . ARG C 1 319 ? -9.201  -29.991 40.260  1.00 68.70  ? 319 ARG C CB  1 
ATOM   9229  C CG  . ARG C 1 319 ? -9.916  -31.255 40.694  1.00 82.80  ? 319 ARG C CG  1 
ATOM   9230  C CD  . ARG C 1 319 ? -11.042 -30.962 41.741  1.00 101.04 ? 319 ARG C CD  1 
ATOM   9231  N NE  . ARG C 1 319 ? -10.645 -30.032 42.817  1.00 119.77 ? 319 ARG C NE  1 
ATOM   9232  C CZ  . ARG C 1 319 ? -11.329 -29.823 43.949  1.00 130.55 ? 319 ARG C CZ  1 
ATOM   9233  N NH1 . ARG C 1 319 ? -12.385 -30.573 44.226  1.00 132.70 ? 319 ARG C NH1 1 
ATOM   9234  N NH2 . ARG C 1 319 ? -10.929 -28.887 44.808  1.00 129.45 ? 319 ARG C NH2 1 
ATOM   9235  N N   . VAL C 1 320 ? -6.939  -32.248 38.723  1.00 60.28  ? 320 VAL C N   1 
ATOM   9236  C CA  . VAL C 1 320 ? -6.518  -33.164 37.680  1.00 56.99  ? 320 VAL C CA  1 
ATOM   9237  C C   . VAL C 1 320 ? -7.345  -34.421 37.800  1.00 53.99  ? 320 VAL C C   1 
ATOM   9238  O O   . VAL C 1 320 ? -7.323  -35.069 38.831  1.00 61.81  ? 320 VAL C O   1 
ATOM   9239  C CB  . VAL C 1 320 ? -5.012  -33.499 37.761  1.00 52.32  ? 320 VAL C CB  1 
ATOM   9240  C CG1 . VAL C 1 320 ? -4.556  -34.297 36.552  1.00 54.38  ? 320 VAL C CG1 1 
ATOM   9241  C CG2 . VAL C 1 320 ? -4.154  -32.241 37.906  1.00 55.22  ? 320 VAL C CG2 1 
ATOM   9242  N N   . GLY C 1 321 ? -8.079  -34.766 36.741  1.00 58.28  ? 321 GLY C N   1 
ATOM   9243  C CA  . GLY C 1 321 ? -8.917  -35.945 36.804  1.00 58.14  ? 321 GLY C CA  1 
ATOM   9244  C C   . GLY C 1 321 ? -9.651  -36.253 35.500  1.00 61.23  ? 321 GLY C C   1 
ATOM   9245  O O   . GLY C 1 321 ? -9.185  -35.940 34.406  1.00 60.35  ? 321 GLY C O   1 
ATOM   9246  N N   . ASP C 1 322 ? -10.754 -36.981 35.671  1.00 54.22  ? 322 ASP C N   1 
ATOM   9247  C CA  . ASP C 1 322 ? -11.611 -37.436 34.606  1.00 59.41  ? 322 ASP C CA  1 
ATOM   9248  C C   . ASP C 1 322 ? -12.183 -36.227 33.856  1.00 61.67  ? 322 ASP C C   1 
ATOM   9249  O O   . ASP C 1 322 ? -12.882 -35.410 34.440  1.00 63.54  ? 322 ASP C O   1 
ATOM   9250  C CB  . ASP C 1 322 ? -12.704 -38.315 35.196  1.00 56.48  ? 322 ASP C CB  1 
ATOM   9251  C CG  . ASP C 1 322 ? -13.810 -38.717 34.258  1.00 59.53  ? 322 ASP C CG  1 
ATOM   9252  O OD1 . ASP C 1 322 ? -14.805 -39.277 34.751  1.00 63.30  ? 322 ASP C OD1 1 
ATOM   9253  O OD2 . ASP C 1 322 ? -13.651 -38.502 33.044  1.00 60.80  ? 322 ASP C OD2 1 
ATOM   9254  N N   . PRO C 1 323 ? -11.971 -36.122 32.525  1.00 61.71  ? 323 PRO C N   1 
ATOM   9255  C CA  . PRO C 1 323 ? -12.414 -34.956 31.771  1.00 56.48  ? 323 PRO C CA  1 
ATOM   9256  C C   . PRO C 1 323 ? -13.935 -34.751 31.703  1.00 52.28  ? 323 PRO C C   1 
ATOM   9257  O O   . PRO C 1 323 ? -14.383 -33.657 31.396  1.00 48.05  ? 323 PRO C O   1 
ATOM   9258  C CB  . PRO C 1 323 ? -11.826 -35.200 30.362  1.00 55.75  ? 323 PRO C CB  1 
ATOM   9259  C CG  . PRO C 1 323 ? -10.837 -36.312 30.539  1.00 58.23  ? 323 PRO C CG  1 
ATOM   9260  C CD  . PRO C 1 323 ? -11.336 -37.130 31.677  1.00 60.13  ? 323 PRO C CD  1 
ATOM   9261  N N   . GLN C 1 324 ? -14.718 -35.819 31.939  1.00 49.47  ? 324 GLN C N   1 
ATOM   9262  C CA  . GLN C 1 324 ? -16.188 -35.731 31.877  1.00 50.75  ? 324 GLN C CA  1 
ATOM   9263  C C   . GLN C 1 324 ? -16.732 -34.836 33.012  1.00 49.63  ? 324 GLN C C   1 
ATOM   9264  O O   . GLN C 1 324 ? -17.809 -34.262 32.888  1.00 51.26  ? 324 GLN C O   1 
ATOM   9265  C CB  . GLN C 1 324 ? -16.831 -37.119 31.930  1.00 49.67  ? 324 GLN C CB  1 
ATOM   9266  C CG  . GLN C 1 324 ? -16.702 -37.901 30.630  1.00 50.96  ? 324 GLN C CG  1 
ATOM   9267  C CD  . GLN C 1 324 ? -17.725 -37.506 29.588  1.00 50.89  ? 324 GLN C CD  1 
ATOM   9268  O OE1 . GLN C 1 324 ? -18.645 -36.730 29.854  1.00 51.51  ? 324 GLN C OE1 1 
ATOM   9269  N NE2 . GLN C 1 324 ? -17.596 -38.068 28.391  1.00 54.59  ? 324 GLN C NE2 1 
ATOM   9270  N N   . ARG C 1 325 ? -15.966 -34.707 34.088  1.00 48.92  ? 325 ARG C N   1 
ATOM   9271  C CA  . ARG C 1 325 ? -16.368 -33.911 35.233  1.00 57.00  ? 325 ARG C CA  1 
ATOM   9272  C C   . ARG C 1 325 ? -16.279 -32.424 34.868  1.00 54.78  ? 325 ARG C C   1 
ATOM   9273  O O   . ARG C 1 325 ? -15.273 -31.978 34.317  1.00 49.72  ? 325 ARG C O   1 
ATOM   9274  C CB  . ARG C 1 325 ? -15.429 -34.209 36.411  1.00 69.65  ? 325 ARG C CB  1 
ATOM   9275  C CG  . ARG C 1 325 ? -15.144 -35.686 36.689  1.00 75.79  ? 325 ARG C CG  1 
ATOM   9276  C CD  . ARG C 1 325 ? -16.053 -36.249 37.746  1.00 81.52  ? 325 ARG C CD  1 
ATOM   9277  N NE  . ARG C 1 325 ? -16.085 -35.384 38.931  1.00 92.75  ? 325 ARG C NE  1 
ATOM   9278  C CZ  . ARG C 1 325 ? -16.895 -35.558 39.966  1.00 95.48  ? 325 ARG C CZ  1 
ATOM   9279  N NH1 . ARG C 1 325 ? -17.659 -36.636 40.042  1.00 96.15  ? 325 ARG C NH1 1 
ATOM   9280  N NH2 . ARG C 1 325 ? -16.932 -34.652 40.921  1.00 96.60  ? 325 ARG C NH2 1 
ATOM   9281  N N   . ALA C 1 326 ? -17.315 -31.658 35.224  1.00 53.49  ? 326 ALA C N   1 
ATOM   9282  C CA  . ALA C 1 326 ? -17.337 -30.224 34.954  1.00 53.67  ? 326 ALA C CA  1 
ATOM   9283  C C   . ALA C 1 326 ? -16.236 -29.503 35.749  1.00 54.35  ? 326 ALA C C   1 
ATOM   9284  O O   . ALA C 1 326 ? -15.760 -28.461 35.330  1.00 58.73  ? 326 ALA C O   1 
ATOM   9285  C CB  . ALA C 1 326 ? -18.715 -29.655 35.262  1.00 51.89  ? 326 ALA C CB  1 
ATOM   9286  N N   . ASP C 1 327 ? -15.805 -30.088 36.870  1.00 62.68  ? 327 ASP C N   1 
ATOM   9287  C CA  . ASP C 1 327 ? -14.844 -29.429 37.759  1.00 65.17  ? 327 ASP C CA  1 
ATOM   9288  C C   . ASP C 1 327 ? -13.406 -29.736 37.344  1.00 58.50  ? 327 ASP C C   1 
ATOM   9289  O O   . ASP C 1 327 ? -12.482 -29.169 37.898  1.00 55.36  ? 327 ASP C O   1 
ATOM   9290  C CB  . ASP C 1 327 ? -15.063 -29.817 39.206  1.00 66.88  ? 327 ASP C CB  1 
ATOM   9291  C CG  . ASP C 1 327 ? -15.384 -31.276 39.427  1.00 71.83  ? 327 ASP C CG  1 
ATOM   9292  O OD1 . ASP C 1 327 ? -16.331 -31.777 38.770  1.00 74.07  ? 327 ASP C OD1 1 
ATOM   9293  O OD2 . ASP C 1 327 ? -14.705 -31.889 40.234  1.00 77.05  ? 327 ASP C OD2 1 
ATOM   9294  N N   . THR C 1 328 ? -13.215 -30.637 36.373  1.00 59.93  ? 328 THR C N   1 
ATOM   9295  C CA  . THR C 1 328 ? -11.854 -31.047 35.991  1.00 54.97  ? 328 THR C CA  1 
ATOM   9296  C C   . THR C 1 328 ? -11.182 -29.920 35.173  1.00 49.72  ? 328 THR C C   1 
ATOM   9297  O O   . THR C 1 328 ? -11.684 -29.512 34.142  1.00 43.57  ? 328 THR C O   1 
ATOM   9298  C CB  . THR C 1 328 ? -11.879 -32.375 35.221  1.00 50.49  ? 328 THR C CB  1 
ATOM   9299  O OG1 . THR C 1 328 ? -12.138 -33.438 36.134  1.00 48.09  ? 328 THR C OG1 1 
ATOM   9300  C CG2 . THR C 1 328 ? -10.539 -32.697 34.598  1.00 51.87  ? 328 THR C CG2 1 
ATOM   9301  N N   . ALA C 1 329 ? -10.016 -29.460 35.638  1.00 50.39  ? 329 ALA C N   1 
ATOM   9302  C CA  . ALA C 1 329 ? -9.221  -28.478 34.900  1.00 44.13  ? 329 ALA C CA  1 
ATOM   9303  C C   . ALA C 1 329 ? -8.270  -29.179 33.923  1.00 45.94  ? 329 ALA C C   1 
ATOM   9304  O O   . ALA C 1 329 ? -8.146  -28.756 32.794  1.00 47.74  ? 329 ALA C O   1 
ATOM   9305  C CB  . ALA C 1 329 ? -8.458  -27.604 35.855  1.00 43.01  ? 329 ALA C CB  1 
ATOM   9306  N N   . VAL C 1 330 ? -7.565  -30.232 34.393  1.00 47.88  ? 330 VAL C N   1 
ATOM   9307  C CA  . VAL C 1 330 ? -6.573  -30.921 33.575  1.00 45.47  ? 330 VAL C CA  1 
ATOM   9308  C C   . VAL C 1 330 ? -7.014  -32.366 33.354  1.00 48.39  ? 330 VAL C C   1 
ATOM   9309  O O   . VAL C 1 330 ? -7.422  -33.054 34.291  1.00 52.18  ? 330 VAL C O   1 
ATOM   9310  C CB  . VAL C 1 330 ? -5.164  -30.876 34.175  1.00 53.54  ? 330 VAL C CB  1 
ATOM   9311  C CG1 . VAL C 1 330 ? -4.129  -31.459 33.218  1.00 49.94  ? 330 VAL C CG1 1 
ATOM   9312  C CG2 . VAL C 1 330 ? -4.763  -29.456 34.575  1.00 58.66  ? 330 VAL C CG2 1 
ATOM   9313  N N   . GLY C 1 331 ? -6.904  -32.811 32.095  1.00 42.50  ? 331 GLY C N   1 
ATOM   9314  C CA  . GLY C 1 331 ? -7.296  -34.152 31.681  1.00 33.25  ? 331 GLY C CA  1 
ATOM   9315  C C   . GLY C 1 331 ? -6.113  -34.870 31.060  1.00 31.41  ? 331 GLY C C   1 
ATOM   9316  O O   . GLY C 1 331 ? -4.973  -34.406 31.179  1.00 30.33  ? 331 GLY C O   1 
ATOM   9317  N N   . PRO C 1 332 ? -6.316  -36.041 30.409  1.00 32.85  ? 332 PRO C N   1 
ATOM   9318  C CA  . PRO C 1 332 ? -5.200  -36.853 29.944  1.00 35.49  ? 332 PRO C CA  1 
ATOM   9319  C C   . PRO C 1 332 ? -4.589  -36.334 28.676  1.00 38.80  ? 332 PRO C C   1 
ATOM   9320  O O   . PRO C 1 332 ? -5.280  -35.758 27.856  1.00 43.84  ? 332 PRO C O   1 
ATOM   9321  C CB  . PRO C 1 332 ? -5.847  -38.180 29.744  1.00 41.68  ? 332 PRO C CB  1 
ATOM   9322  C CG  . PRO C 1 332 ? -7.219  -37.831 29.258  1.00 38.79  ? 332 PRO C CG  1 
ATOM   9323  C CD  . PRO C 1 332 ? -7.601  -36.646 30.122  1.00 34.57  ? 332 PRO C CD  1 
ATOM   9324  N N   . ILE C 1 333 ? -3.288  -36.596 28.509  1.00 44.82  ? 333 ILE C N   1 
ATOM   9325  C CA  . ILE C 1 333 ? -2.603  -36.381 27.244  1.00 44.64  ? 333 ILE C CA  1 
ATOM   9326  C C   . ILE C 1 333 ? -3.168  -37.352 26.198  1.00 49.58  ? 333 ILE C C   1 
ATOM   9327  O O   . ILE C 1 333 ? -3.579  -38.462 26.526  1.00 52.89  ? 333 ILE C O   1 
ATOM   9328  C CB  . ILE C 1 333 ? -1.091  -36.531 27.433  1.00 43.59  ? 333 ILE C CB  1 
ATOM   9329  C CG1 . ILE C 1 333 ? -0.611  -35.682 28.575  1.00 44.20  ? 333 ILE C CG1 1 
ATOM   9330  C CG2 . ILE C 1 333 ? -0.327  -36.205 26.152  1.00 43.89  ? 333 ILE C CG2 1 
ATOM   9331  C CD1 . ILE C 1 333 ? -0.884  -34.206 28.380  1.00 42.72  ? 333 ILE C CD1 1 
ATOM   9332  N N   . VAL C 1 334 ? -3.195  -36.903 24.944  1.00 50.96  ? 334 VAL C N   1 
ATOM   9333  C CA  . VAL C 1 334 ? -3.969  -37.554 23.897  1.00 52.73  ? 334 VAL C CA  1 
ATOM   9334  C C   . VAL C 1 334 ? -3.415  -38.963 23.609  1.00 47.88  ? 334 VAL C C   1 
ATOM   9335  O O   . VAL C 1 334 ? -4.187  -39.904 23.416  1.00 48.81  ? 334 VAL C O   1 
ATOM   9336  C CB  . VAL C 1 334 ? -4.002  -36.708 22.616  1.00 54.85  ? 334 VAL C CB  1 
ATOM   9337  C CG1 . VAL C 1 334 ? -2.602  -36.239 22.205  1.00 60.76  ? 334 VAL C CG1 1 
ATOM   9338  C CG2 . VAL C 1 334 ? -4.682  -37.462 21.475  1.00 58.39  ? 334 VAL C CG2 1 
ATOM   9339  N N   . ASN C 1 335 ? -2.091  -39.099 23.526  1.00 47.76  ? 335 ASN C N   1 
ATOM   9340  C CA  . ASN C 1 335 ? -1.503  -40.407 23.216  1.00 54.92  ? 335 ASN C CA  1 
ATOM   9341  C C   . ASN C 1 335 ? -0.165  -40.556 23.911  1.00 55.94  ? 335 ASN C C   1 
ATOM   9342  O O   . ASN C 1 335 ? 0.369   -39.594 24.475  1.00 64.53  ? 335 ASN C O   1 
ATOM   9343  C CB  . ASN C 1 335 ? -1.366  -40.649 21.707  1.00 52.28  ? 335 ASN C CB  1 
ATOM   9344  C CG  . ASN C 1 335 ? -0.349  -39.740 21.058  1.00 46.26  ? 335 ASN C CG  1 
ATOM   9345  O OD1 . ASN C 1 335 ? 0.749   -39.567 21.573  1.00 48.32  ? 335 ASN C OD1 1 
ATOM   9346  N ND2 . ASN C 1 335 ? -0.684  -39.188 19.914  1.00 49.60  ? 335 ASN C ND2 1 
ATOM   9347  N N   . ALA C 1 336 ? 0.383   -41.771 23.823  1.00 54.50  ? 336 ALA C N   1 
ATOM   9348  C CA  . ALA C 1 336 ? 1.550   -42.164 24.593  1.00 57.52  ? 336 ALA C CA  1 
ATOM   9349  C C   . ALA C 1 336 ? 2.800   -41.451 24.086  1.00 51.97  ? 336 ALA C C   1 
ATOM   9350  O O   . ALA C 1 336 ? 3.649   -41.076 24.875  1.00 59.94  ? 336 ALA C O   1 
ATOM   9351  C CB  . ALA C 1 336 ? 1.713   -43.661 24.541  1.00 60.31  ? 336 ALA C CB  1 
ATOM   9352  N N   . ARG C 1 337 ? 2.909   -41.296 22.765  1.00 51.96  ? 337 ARG C N   1 
ATOM   9353  C CA  . ARG C 1 337 ? 4.066   -40.637 22.147  1.00 57.84  ? 337 ARG C CA  1 
ATOM   9354  C C   . ARG C 1 337 ? 4.144   -39.194 22.638  1.00 54.16  ? 337 ARG C C   1 
ATOM   9355  O O   . ARG C 1 337 ? 5.230   -38.658 22.914  1.00 53.16  ? 337 ARG C O   1 
ATOM   9356  C CB  . ARG C 1 337 ? 3.942   -40.681 20.610  1.00 57.01  ? 337 ARG C CB  1 
ATOM   9357  C CG  . ARG C 1 337 ? 5.163   -40.166 19.856  1.00 65.64  ? 337 ARG C CG  1 
ATOM   9358  C CD  . ARG C 1 337 ? 5.291   -40.783 18.434  1.00 83.66  ? 337 ARG C CD  1 
ATOM   9359  N NE  . ARG C 1 337 ? 6.672   -40.741 17.906  1.00 97.83  ? 337 ARG C NE  1 
ATOM   9360  C CZ  . ARG C 1 337 ? 7.747   -41.397 18.433  1.00 98.36  ? 337 ARG C CZ  1 
ATOM   9361  N NH1 . ARG C 1 337 ? 7.603   -42.188 19.482  1.00 93.79  ? 337 ARG C NH1 1 
ATOM   9362  N NH2 . ARG C 1 337 ? 8.952   -41.244 17.901  1.00 95.12  ? 337 ARG C NH2 1 
ATOM   9363  N N   . GLN C 1 338 ? 2.974   -38.581 22.695  1.00 58.39  ? 338 GLN C N   1 
ATOM   9364  C CA  . GLN C 1 338 ? 2.807   -37.182 23.026  1.00 58.41  ? 338 GLN C CA  1 
ATOM   9365  C C   . GLN C 1 338 ? 3.221   -36.974 24.479  1.00 53.58  ? 338 GLN C C   1 
ATOM   9366  O O   . GLN C 1 338 ? 3.999   -36.081 24.797  1.00 43.77  ? 338 GLN C O   1 
ATOM   9367  C CB  . GLN C 1 338 ? 1.328   -36.862 22.741  1.00 73.80  ? 338 GLN C CB  1 
ATOM   9368  C CG  . GLN C 1 338 ? 1.014   -36.660 21.255  1.00 89.26  ? 338 GLN C CG  1 
ATOM   9369  C CD  . GLN C 1 338 ? 1.653   -35.408 20.670  1.00 93.44  ? 338 GLN C CD  1 
ATOM   9370  O OE1 . GLN C 1 338 ? 1.824   -35.282 19.451  1.00 111.80 ? 338 GLN C OE1 1 
ATOM   9371  N NE2 . GLN C 1 338 ? 1.996   -34.459 21.532  1.00 84.48  ? 338 GLN C NE2 1 
ATOM   9372  N N   . LEU C 1 339 ? 2.763   -37.885 25.333  1.00 52.75  ? 339 LEU C N   1 
ATOM   9373  C CA  . LEU C 1 339 ? 3.093   -37.871 26.744  1.00 55.25  ? 339 LEU C CA  1 
ATOM   9374  C C   . LEU C 1 339 ? 4.601   -37.960 26.939  1.00 57.15  ? 339 LEU C C   1 
ATOM   9375  O O   . LEU C 1 339 ? 5.151   -37.261 27.767  1.00 62.85  ? 339 LEU C O   1 
ATOM   9376  C CB  . LEU C 1 339 ? 2.371   -39.008 27.468  1.00 52.19  ? 339 LEU C CB  1 
ATOM   9377  C CG  . LEU C 1 339 ? 2.801   -39.286 28.913  1.00 51.91  ? 339 LEU C CG  1 
ATOM   9378  C CD1 . LEU C 1 339 ? 2.240   -38.240 29.901  1.00 54.58  ? 339 LEU C CD1 1 
ATOM   9379  C CD2 . LEU C 1 339 ? 2.358   -40.701 29.312  1.00 50.66  ? 339 LEU C CD2 1 
ATOM   9380  N N   . GLU C 1 340 ? 5.268   -38.865 26.262  1.00 58.78  ? 340 GLU C N   1 
ATOM   9381  C CA  . GLU C 1 340 ? 6.623   -39.141 26.689  1.00 64.20  ? 340 GLU C CA  1 
ATOM   9382  C C   . GLU C 1 340 ? 7.599   -38.278 25.903  1.00 57.81  ? 340 GLU C C   1 
ATOM   9383  O O   . GLU C 1 340 ? 8.765   -38.249 26.227  1.00 67.18  ? 340 GLU C O   1 
ATOM   9384  C CB  . GLU C 1 340 ? 6.907   -40.638 26.799  1.00 77.79  ? 340 GLU C CB  1 
ATOM   9385  C CG  . GLU C 1 340 ? 7.637   -41.273 25.616  1.00 83.44  ? 340 GLU C CG  1 
ATOM   9386  C CD  . GLU C 1 340 ? 7.428   -42.759 25.599  1.00 97.61  ? 340 GLU C CD  1 
ATOM   9387  O OE1 . GLU C 1 340 ? 8.093   -43.460 24.817  1.00 107.97 ? 340 GLU C OE1 1 
ATOM   9388  O OE2 . GLU C 1 340 ? 6.577   -43.213 26.389  1.00 106.63 ? 340 GLU C OE2 1 
ATOM   9389  N N   . GLY C 1 341 ? 7.079   -37.445 24.994  1.00 61.64  ? 341 GLY C N   1 
ATOM   9390  C CA  . GLY C 1 341 ? 7.789   -36.244 24.579  1.00 57.94  ? 341 GLY C CA  1 
ATOM   9391  C C   . GLY C 1 341 ? 7.820   -35.207 25.712  1.00 55.33  ? 341 GLY C C   1 
ATOM   9392  O O   . GLY C 1 341 ? 8.813   -34.538 25.917  1.00 56.52  ? 341 GLY C O   1 
ATOM   9393  N N   . LEU C 1 342 ? 6.721   -35.109 26.453  1.00 47.39  ? 342 LEU C N   1 
ATOM   9394  C CA  . LEU C 1 342 ? 6.597   -34.130 27.511  1.00 49.24  ? 342 LEU C CA  1 
ATOM   9395  C C   . LEU C 1 342 ? 7.520   -34.495 28.690  1.00 53.90  ? 342 LEU C C   1 
ATOM   9396  O O   . LEU C 1 342 ? 8.124   -33.598 29.303  1.00 46.05  ? 342 LEU C O   1 
ATOM   9397  C CB  . LEU C 1 342 ? 5.128   -34.037 27.931  1.00 44.82  ? 342 LEU C CB  1 
ATOM   9398  C CG  . LEU C 1 342 ? 4.197   -33.406 26.903  1.00 43.52  ? 342 LEU C CG  1 
ATOM   9399  C CD1 . LEU C 1 342 ? 2.770   -33.686 27.203  1.00 42.46  ? 342 LEU C CD1 1 
ATOM   9400  C CD2 . LEU C 1 342 ? 4.456   -31.917 26.830  1.00 45.25  ? 342 LEU C CD2 1 
ATOM   9401  N N   . LEU C 1 343 ? 7.614   -35.813 29.009  1.00 51.54  ? 343 LEU C N   1 
ATOM   9402  C CA  . LEU C 1 343 ? 8.495   -36.287 30.081  1.00 53.78  ? 343 LEU C CA  1 
ATOM   9403  C C   . LEU C 1 343 ? 9.940   -35.904 29.768  1.00 62.86  ? 343 LEU C C   1 
ATOM   9404  O O   . LEU C 1 343 ? 10.684  -35.512 30.665  1.00 68.21  ? 343 LEU C O   1 
ATOM   9405  C CB  . LEU C 1 343 ? 8.368   -37.789 30.304  1.00 53.39  ? 343 LEU C CB  1 
ATOM   9406  C CG  . LEU C 1 343 ? 7.201   -38.261 31.195  1.00 57.50  ? 343 LEU C CG  1 
ATOM   9407  C CD1 . LEU C 1 343 ? 6.909   -37.277 32.341  1.00 57.53  ? 343 LEU C CD1 1 
ATOM   9408  C CD2 . LEU C 1 343 ? 5.951   -38.516 30.387  1.00 62.83  ? 343 LEU C CD2 1 
ATOM   9409  N N   . GLU C 1 344 ? 10.325  -35.996 28.487  1.00 60.38  ? 344 GLU C N   1 
ATOM   9410  C CA  . GLU C 1 344 ? 11.684  -35.682 28.080  1.00 60.94  ? 344 GLU C CA  1 
ATOM   9411  C C   . GLU C 1 344 ? 11.944  -34.190 28.272  1.00 60.52  ? 344 GLU C C   1 
ATOM   9412  O O   . GLU C 1 344 ? 13.026  -33.802 28.681  1.00 65.17  ? 344 GLU C O   1 
ATOM   9413  C CB  . GLU C 1 344 ? 11.945  -36.125 26.633  1.00 67.66  ? 344 GLU C CB  1 
ATOM   9414  C CG  . GLU C 1 344 ? 13.323  -35.716 26.088  1.00 71.61  ? 344 GLU C CG  1 
ATOM   9415  C CD  . GLU C 1 344 ? 14.555  -36.426 26.686  1.00 70.53  ? 344 GLU C CD  1 
ATOM   9416  O OE1 . GLU C 1 344 ? 14.437  -37.158 27.709  1.00 61.35  ? 344 GLU C OE1 1 
ATOM   9417  O OE2 . GLU C 1 344 ? 15.651  -36.230 26.106  1.00 75.77  ? 344 GLU C OE2 1 
ATOM   9418  N N   . LYS C 1 345 ? 10.945  -33.359 27.960  1.00 65.65  ? 345 LYS C N   1 
ATOM   9419  C CA  . LYS C 1 345 ? 11.095  -31.906 28.052  1.00 59.31  ? 345 LYS C CA  1 
ATOM   9420  C C   . LYS C 1 345 ? 11.296  -31.498 29.505  1.00 55.19  ? 345 LYS C C   1 
ATOM   9421  O O   . LYS C 1 345 ? 12.132  -30.635 29.798  1.00 49.62  ? 345 LYS C O   1 
ATOM   9422  C CB  . LYS C 1 345 ? 9.907   -31.176 27.425  1.00 61.56  ? 345 LYS C CB  1 
ATOM   9423  C CG  . LYS C 1 345 ? 10.223  -30.544 26.081  1.00 67.86  ? 345 LYS C CG  1 
ATOM   9424  C CD  . LYS C 1 345 ? 9.088   -30.592 25.059  1.00 75.92  ? 345 LYS C CD  1 
ATOM   9425  C CE  . LYS C 1 345 ? 9.488   -30.021 23.708  1.00 75.31  ? 345 LYS C CE  1 
ATOM   9426  N NZ  . LYS C 1 345 ? 9.755   -28.573 23.754  1.00 75.35  ? 345 LYS C NZ  1 
ATOM   9427  N N   . ILE C 1 346 ? 10.555  -32.149 30.405  1.00 47.81  ? 346 ILE C N   1 
ATOM   9428  C CA  . ILE C 1 346 ? 10.697  -31.900 31.827  1.00 55.63  ? 346 ILE C CA  1 
ATOM   9429  C C   . ILE C 1 346 ? 12.124  -32.244 32.254  1.00 67.08  ? 346 ILE C C   1 
ATOM   9430  O O   . ILE C 1 346 ? 12.799  -31.427 32.877  1.00 74.03  ? 346 ILE C O   1 
ATOM   9431  C CB  . ILE C 1 346 ? 9.656   -32.692 32.638  1.00 52.92  ? 346 ILE C CB  1 
ATOM   9432  C CG1 . ILE C 1 346 ? 8.218   -32.239 32.312  1.00 47.20  ? 346 ILE C CG1 1 
ATOM   9433  C CG2 . ILE C 1 346 ? 9.956   -32.601 34.136  1.00 54.75  ? 346 ILE C CG2 1 
ATOM   9434  C CD1 . ILE C 1 346 ? 7.137   -33.166 32.833  1.00 45.58  ? 346 ILE C CD1 1 
ATOM   9435  N N   . ARG C 1 347 ? 12.569  -33.468 31.916  1.00 75.40  ? 347 ARG C N   1 
ATOM   9436  C CA  . ARG C 1 347 ? 13.867  -33.969 32.355  1.00 71.94  ? 347 ARG C CA  1 
ATOM   9437  C C   . ARG C 1 347 ? 14.979  -33.077 31.808  1.00 61.78  ? 347 ARG C C   1 
ATOM   9438  O O   . ARG C 1 347 ? 15.887  -32.728 32.529  1.00 62.16  ? 347 ARG C O   1 
ATOM   9439  C CB  . ARG C 1 347 ? 14.103  -35.421 31.925  1.00 80.85  ? 347 ARG C CB  1 
ATOM   9440  C CG  . ARG C 1 347 ? 15.432  -35.989 32.420  1.00 89.80  ? 347 ARG C CG  1 
ATOM   9441  C CD  . ARG C 1 347 ? 16.090  -36.909 31.415  1.00 91.25  ? 347 ARG C CD  1 
ATOM   9442  N NE  . ARG C 1 347 ? 16.407  -36.206 30.167  1.00 92.40  ? 347 ARG C NE  1 
ATOM   9443  C CZ  . ARG C 1 347 ? 17.612  -35.744 29.832  1.00 90.50  ? 347 ARG C CZ  1 
ATOM   9444  N NH1 . ARG C 1 347 ? 18.638  -35.896 30.658  1.00 87.81  ? 347 ARG C NH1 1 
ATOM   9445  N NH2 . ARG C 1 347 ? 17.786  -35.133 28.672  1.00 81.59  ? 347 ARG C NH2 1 
ATOM   9446  N N   . LEU C 1 348 ? 14.889  -32.711 30.533  1.00 59.20  ? 348 LEU C N   1 
ATOM   9447  C CA  . LEU C 1 348 ? 15.898  -31.858 29.909  1.00 67.13  ? 348 LEU C CA  1 
ATOM   9448  C C   . LEU C 1 348 ? 15.976  -30.489 30.631  1.00 70.36  ? 348 LEU C C   1 
ATOM   9449  O O   . LEU C 1 348 ? 17.063  -29.945 30.822  1.00 76.29  ? 348 LEU C O   1 
ATOM   9450  C CB  . LEU C 1 348 ? 15.568  -31.713 28.419  1.00 67.85  ? 348 LEU C CB  1 
ATOM   9451  C CG  . LEU C 1 348 ? 16.610  -30.992 27.544  1.00 70.14  ? 348 LEU C CG  1 
ATOM   9452  C CD1 . LEU C 1 348 ? 18.058  -31.431 27.836  1.00 64.40  ? 348 LEU C CD1 1 
ATOM   9453  C CD2 . LEU C 1 348 ? 16.270  -31.207 26.067  1.00 69.17  ? 348 LEU C CD2 1 
ATOM   9454  N N   . ALA C 1 349 ? 14.816  -29.941 31.020  1.00 78.97  ? 349 ALA C N   1 
ATOM   9455  C CA  . ALA C 1 349 ? 14.764  -28.660 31.717  1.00 71.87  ? 349 ALA C CA  1 
ATOM   9456  C C   . ALA C 1 349 ? 15.542  -28.744 33.043  1.00 72.77  ? 349 ALA C C   1 
ATOM   9457  O O   . ALA C 1 349 ? 16.311  -27.840 33.381  1.00 57.94  ? 349 ALA C O   1 
ATOM   9458  C CB  . ALA C 1 349 ? 13.317  -28.252 31.947  1.00 66.49  ? 349 ALA C CB  1 
ATOM   9459  N N   . ARG C 1 350 ? 15.333  -29.834 33.789  1.00 67.72  ? 350 ARG C N   1 
ATOM   9460  C CA  . ARG C 1 350 ? 16.019  -30.027 35.056  1.00 67.86  ? 350 ARG C CA  1 
ATOM   9461  C C   . ARG C 1 350 ? 17.532  -29.984 34.836  1.00 73.87  ? 350 ARG C C   1 
ATOM   9462  O O   . ARG C 1 350 ? 18.248  -29.327 35.575  1.00 75.83  ? 350 ARG C O   1 
ATOM   9463  C CB  . ARG C 1 350 ? 15.609  -31.352 35.702  1.00 50.00  ? 350 ARG C CB  1 
ATOM   9464  C CG  . ARG C 1 350 ? 14.505  -31.222 36.738  1.00 50.00  ? 350 ARG C CG  1 
ATOM   9465  C CD  . ARG C 1 350 ? 14.131  -32.531 37.415  1.00 50.00  ? 350 ARG C CD  1 
ATOM   9466  N NE  . ARG C 1 350 ? 14.622  -32.598 38.788  1.00 50.00  ? 350 ARG C NE  1 
ATOM   9467  C CZ  . ARG C 1 350 ? 14.207  -31.808 39.767  1.00 50.00  ? 350 ARG C CZ  1 
ATOM   9468  N NH1 . ARG C 1 350 ? 13.283  -30.885 39.532  1.00 50.00  ? 350 ARG C NH1 1 
ATOM   9469  N NH2 . ARG C 1 350 ? 14.710  -31.940 40.988  1.00 50.00  ? 350 ARG C NH2 1 
ATOM   9470  N N   . GLN C 1 351 ? 18.022  -30.666 33.821  1.00 76.75  ? 351 GLN C N   1 
ATOM   9471  C CA  . GLN C 1 351 ? 19.456  -30.837 33.716  1.00 84.56  ? 351 GLN C CA  1 
ATOM   9472  C C   . GLN C 1 351 ? 20.076  -29.646 33.006  1.00 79.01  ? 351 GLN C C   1 
ATOM   9473  O O   . GLN C 1 351 ? 21.270  -29.444 33.088  1.00 84.35  ? 351 GLN C O   1 
ATOM   9474  C CB  . GLN C 1 351 ? 19.823  -32.158 33.062  1.00 105.36 ? 351 GLN C CB  1 
ATOM   9475  C CG  . GLN C 1 351 ? 19.110  -33.363 33.672  1.00 117.07 ? 351 GLN C CG  1 
ATOM   9476  C CD  . GLN C 1 351 ? 19.751  -33.864 34.950  1.00 131.74 ? 351 GLN C CD  1 
ATOM   9477  O OE1 . GLN C 1 351 ? 19.722  -33.201 35.993  1.00 140.12 ? 351 GLN C OE1 1 
ATOM   9478  N NE2 . GLN C 1 351 ? 20.321  -35.057 34.884  1.00 139.61 ? 351 GLN C NE2 1 
ATOM   9479  N N   . GLU C 1 352 ? 19.257  -28.823 32.362  1.00 75.16  ? 352 GLU C N   1 
ATOM   9480  C CA  . GLU C 1 352 ? 19.756  -27.574 31.813  1.00 68.97  ? 352 GLU C CA  1 
ATOM   9481  C C   . GLU C 1 352 ? 19.820  -26.513 32.916  1.00 64.12  ? 352 GLU C C   1 
ATOM   9482  O O   . GLU C 1 352 ? 20.336  -25.417 32.679  1.00 52.81  ? 352 GLU C O   1 
ATOM   9483  C CB  . GLU C 1 352 ? 18.913  -27.085 30.644  1.00 73.29  ? 352 GLU C CB  1 
ATOM   9484  C CG  . GLU C 1 352 ? 19.201  -27.807 29.336  1.00 73.44  ? 352 GLU C CG  1 
ATOM   9485  C CD  . GLU C 1 352 ? 18.273  -27.373 28.231  1.00 74.26  ? 352 GLU C CD  1 
ATOM   9486  O OE1 . GLU C 1 352 ? 17.040  -27.500 28.432  1.00 83.78  ? 352 GLU C OE1 1 
ATOM   9487  O OE2 . GLU C 1 352 ? 18.763  -26.854 27.206  1.00 65.76  ? 352 GLU C OE2 1 
ATOM   9488  N N   . GLY C 1 353 ? 19.266  -26.843 34.111  1.00 62.33  ? 353 GLY C N   1 
ATOM   9489  C CA  . GLY C 1 353 ? 19.459  -26.030 35.317  1.00 67.52  ? 353 GLY C CA  1 
ATOM   9490  C C   . GLY C 1 353 ? 18.233  -25.151 35.673  1.00 74.78  ? 353 GLY C C   1 
ATOM   9491  O O   . GLY C 1 353 ? 18.335  -24.274 36.525  1.00 68.91  ? 353 GLY C O   1 
ATOM   9492  N N   . ALA C 1 354 ? 17.066  -25.426 35.064  1.00 81.35  ? 354 ALA C N   1 
ATOM   9493  C CA  . ALA C 1 354 ? 15.840  -24.704 35.404  1.00 75.68  ? 354 ALA C CA  1 
ATOM   9494  C C   . ALA C 1 354 ? 15.440  -25.009 36.842  1.00 74.22  ? 354 ALA C C   1 
ATOM   9495  O O   . ALA C 1 354 ? 15.452  -26.165 37.258  1.00 74.23  ? 354 ALA C O   1 
ATOM   9496  C CB  . ALA C 1 354 ? 14.712  -25.069 34.449  1.00 79.13  ? 354 ALA C CB  1 
ATOM   9497  N N   . LYS C 1 355 ? 15.018  -23.961 37.562  1.00 73.50  ? 355 LYS C N   1 
ATOM   9498  C CA  . LYS C 1 355 ? 14.616  -24.072 38.954  1.00 70.25  ? 355 LYS C CA  1 
ATOM   9499  C C   . LYS C 1 355 ? 13.183  -24.556 39.016  1.00 64.34  ? 355 LYS C C   1 
ATOM   9500  O O   . LYS C 1 355 ? 12.283  -23.845 38.619  1.00 68.25  ? 355 LYS C O   1 
ATOM   9501  C CB  . LYS C 1 355 ? 14.763  -22.705 39.632  1.00 80.06  ? 355 LYS C CB  1 
ATOM   9502  C CG  . LYS C 1 355 ? 14.276  -22.607 41.088  1.00 87.87  ? 355 LYS C CG  1 
ATOM   9503  C CD  . LYS C 1 355 ? 14.870  -21.396 41.838  1.00 85.18  ? 355 LYS C CD  1 
ATOM   9504  C CE  . LYS C 1 355 ? 14.034  -20.904 42.991  1.00 74.08  ? 355 LYS C CE  1 
ATOM   9505  N NZ  . LYS C 1 355 ? 13.447  -22.012 43.748  1.00 74.65  ? 355 LYS C NZ  1 
ATOM   9506  N N   . PRO C 1 356 ? 12.935  -25.790 39.483  1.00 70.10  ? 356 PRO C N   1 
ATOM   9507  C CA  . PRO C 1 356 ? 11.586  -26.351 39.493  1.00 65.13  ? 356 PRO C CA  1 
ATOM   9508  C C   . PRO C 1 356 ? 10.695  -25.712 40.542  1.00 71.10  ? 356 PRO C C   1 
ATOM   9509  O O   . PRO C 1 356 ? 10.838  -25.999 41.725  1.00 84.00  ? 356 PRO C O   1 
ATOM   9510  C CB  . PRO C 1 356 ? 11.837  -27.864 39.797  1.00 69.25  ? 356 PRO C CB  1 
ATOM   9511  C CG  . PRO C 1 356 ? 13.340  -28.059 39.565  1.00 66.40  ? 356 PRO C CG  1 
ATOM   9512  C CD  . PRO C 1 356 ? 13.950  -26.747 39.945  1.00 68.75  ? 356 PRO C CD  1 
ATOM   9513  N N   . LEU C 1 357 ? 9.725   -24.905 40.094  1.00 66.38  ? 357 LEU C N   1 
ATOM   9514  C CA  . LEU C 1 357 ? 8.833   -24.216 41.015  1.00 55.66  ? 357 LEU C CA  1 
ATOM   9515  C C   . LEU C 1 357 ? 7.745   -25.175 41.495  1.00 57.71  ? 357 LEU C C   1 
ATOM   9516  O O   . LEU C 1 357 ? 7.483   -25.250 42.684  1.00 68.81  ? 357 LEU C O   1 
ATOM   9517  C CB  . LEU C 1 357 ? 8.250   -22.970 40.370  1.00 53.01  ? 357 LEU C CB  1 
ATOM   9518  C CG  . LEU C 1 357 ? 9.275   -21.990 39.797  1.00 57.55  ? 357 LEU C CG  1 
ATOM   9519  C CD1 . LEU C 1 357 ? 8.647   -20.660 39.502  1.00 63.57  ? 357 LEU C CD1 1 
ATOM   9520  C CD2 . LEU C 1 357 ? 10.438  -21.819 40.729  1.00 57.40  ? 357 LEU C CD2 1 
ATOM   9521  N N   . TYR C 1 358 ? 7.102   -25.893 40.567  1.00 54.33  ? 358 TYR C N   1 
ATOM   9522  C CA  . TYR C 1 358 ? 6.080   -26.864 40.943  1.00 49.65  ? 358 TYR C CA  1 
ATOM   9523  C C   . TYR C 1 358 ? 6.113   -28.034 39.980  1.00 56.53  ? 358 TYR C C   1 
ATOM   9524  O O   . TYR C 1 358 ? 6.183   -27.836 38.769  1.00 65.20  ? 358 TYR C O   1 
ATOM   9525  C CB  . TYR C 1 358 ? 4.663   -26.297 40.950  1.00 48.70  ? 358 TYR C CB  1 
ATOM   9526  C CG  . TYR C 1 358 ? 3.613   -27.353 41.264  1.00 45.67  ? 358 TYR C CG  1 
ATOM   9527  C CD1 . TYR C 1 358 ? 3.576   -27.970 42.509  1.00 44.43  ? 358 TYR C CD1 1 
ATOM   9528  C CD2 . TYR C 1 358 ? 2.675   -27.752 40.312  1.00 42.93  ? 358 TYR C CD2 1 
ATOM   9529  C CE1 . TYR C 1 358 ? 2.651   -28.958 42.803  1.00 43.04  ? 358 TYR C CE1 1 
ATOM   9530  C CE2 . TYR C 1 358 ? 1.730   -28.725 40.600  1.00 42.30  ? 358 TYR C CE2 1 
ATOM   9531  C CZ  . TYR C 1 358 ? 1.734   -29.345 41.850  1.00 43.20  ? 358 TYR C CZ  1 
ATOM   9532  O OH  . TYR C 1 358 ? 0.810   -30.296 42.174  1.00 50.76  ? 358 TYR C OH  1 
ATOM   9533  N N   . GLU C 1 359 ? 6.042   -29.255 40.545  1.00 56.11  ? 359 GLU C N   1 
ATOM   9534  C CA  . GLU C 1 359 ? 6.024   -30.491 39.779  1.00 55.77  ? 359 GLU C CA  1 
ATOM   9535  C C   . GLU C 1 359 ? 4.935   -31.393 40.318  1.00 53.82  ? 359 GLU C C   1 
ATOM   9536  O O   . GLU C 1 359 ? 4.958   -31.768 41.472  1.00 68.92  ? 359 GLU C O   1 
ATOM   9537  C CB  . GLU C 1 359 ? 7.361   -31.213 39.850  1.00 59.87  ? 359 GLU C CB  1 
ATOM   9538  C CG  . GLU C 1 359 ? 8.495   -30.414 39.219  1.00 65.43  ? 359 GLU C CG  1 
ATOM   9539  C CD  . GLU C 1 359 ? 9.653   -31.260 38.801  1.00 69.44  ? 359 GLU C CD  1 
ATOM   9540  O OE1 . GLU C 1 359 ? 9.397   -32.277 38.148  1.00 90.36  ? 359 GLU C OE1 1 
ATOM   9541  O OE2 . GLU C 1 359 ? 10.811  -30.896 39.097  1.00 72.42  ? 359 GLU C OE2 1 
ATOM   9542  N N   . GLY C 1 360 ? 3.973   -31.713 39.472  1.00 54.02  ? 360 GLY C N   1 
ATOM   9543  C CA  . GLY C 1 360 ? 2.884   -32.576 39.851  1.00 56.57  ? 360 GLY C CA  1 
ATOM   9544  C C   . GLY C 1 360 ? 3.150   -34.005 39.402  1.00 62.52  ? 360 GLY C C   1 
ATOM   9545  O O   . GLY C 1 360 ? 3.934   -34.249 38.470  1.00 64.75  ? 360 GLY C O   1 
ATOM   9546  N N   . GLY C 1 361 ? 2.460   -34.939 40.033  1.00 64.52  ? 361 GLY C N   1 
ATOM   9547  C CA  . GLY C 1 361 ? 2.666   -36.347 39.746  1.00 87.12  ? 361 GLY C CA  1 
ATOM   9548  C C   . GLY C 1 361 ? 1.977   -36.766 38.445  1.00 91.90  ? 361 GLY C C   1 
ATOM   9549  O O   . GLY C 1 361 ? 0.804   -36.461 38.242  1.00 115.24 ? 361 GLY C O   1 
ATOM   9550  N N   . VAL C 1 362 ? 2.710   -37.528 37.607  1.00 74.96  ? 362 VAL C N   1 
ATOM   9551  C CA  . VAL C 1 362 ? 2.133   -38.210 36.458  1.00 65.82  ? 362 VAL C CA  1 
ATOM   9552  C C   . VAL C 1 362 ? 1.608   -39.586 36.882  1.00 59.33  ? 362 VAL C C   1 
ATOM   9553  O O   . VAL C 1 362 ? 2.338   -40.375 37.468  1.00 67.42  ? 362 VAL C O   1 
ATOM   9554  C CB  . VAL C 1 362 ? 3.152   -38.343 35.314  1.00 64.60  ? 362 VAL C CB  1 
ATOM   9555  C CG1 . VAL C 1 362 ? 4.429   -39.071 35.744  1.00 60.08  ? 362 VAL C CG1 1 
ATOM   9556  C CG2 . VAL C 1 362 ? 2.535   -39.013 34.100  1.00 61.66  ? 362 VAL C CG2 1 
ATOM   9557  N N   . ASP C 1 363 ? 0.340   -39.856 36.545  1.00 55.47  ? 363 ASP C N   1 
ATOM   9558  C CA  . ASP C 1 363 ? -0.305  -41.127 36.827  1.00 61.81  ? 363 ASP C CA  1 
ATOM   9559  C C   . ASP C 1 363 ? -1.016  -41.597 35.550  1.00 66.00  ? 363 ASP C C   1 
ATOM   9560  O O   . ASP C 1 363 ? -2.083  -41.114 35.229  1.00 65.03  ? 363 ASP C O   1 
ATOM   9561  C CB  . ASP C 1 363 ? -1.259  -40.999 38.016  1.00 69.37  ? 363 ASP C CB  1 
ATOM   9562  C CG  . ASP C 1 363 ? -2.133  -42.215 38.322  1.00 81.65  ? 363 ASP C CG  1 
ATOM   9563  O OD1 . ASP C 1 363 ? -3.056  -42.077 39.168  1.00 84.79  ? 363 ASP C OD1 1 
ATOM   9564  O OD2 . ASP C 1 363 ? -1.891  -43.292 37.714  1.00 81.90  ? 363 ASP C OD2 1 
ATOM   9565  N N   . GLY C 1 364 ? -0.413  -42.559 34.831  1.00 70.39  ? 364 GLY C N   1 
ATOM   9566  C CA  . GLY C 1 364 ? -0.951  -43.011 33.548  1.00 62.34  ? 364 GLY C CA  1 
ATOM   9567  C C   . GLY C 1 364 ? -0.851  -41.905 32.492  1.00 62.55  ? 364 GLY C C   1 
ATOM   9568  O O   . GLY C 1 364 ? 0.210   -41.296 32.331  1.00 56.48  ? 364 GLY C O   1 
ATOM   9569  N N   . GLN C 1 365 ? -1.984  -41.604 31.822  1.00 57.83  ? 365 GLN C N   1 
ATOM   9570  C CA  . GLN C 1 365 ? -2.025  -40.516 30.837  1.00 53.54  ? 365 GLN C CA  1 
ATOM   9571  C C   . GLN C 1 365 ? -2.165  -39.147 31.537  1.00 56.81  ? 365 GLN C C   1 
ATOM   9572  O O   . GLN C 1 365 ? -1.840  -38.128 30.947  1.00 61.04  ? 365 GLN C O   1 
ATOM   9573  C CB  . GLN C 1 365 ? -3.149  -40.702 29.827  1.00 49.26  ? 365 GLN C CB  1 
ATOM   9574  C CG  . GLN C 1 365 ? -2.870  -41.773 28.766  1.00 49.34  ? 365 GLN C CG  1 
ATOM   9575  C CD  . GLN C 1 365 ? -1.621  -41.506 27.969  1.00 52.25  ? 365 GLN C CD  1 
ATOM   9576  O OE1 . GLN C 1 365 ? -0.652  -42.267 28.032  1.00 45.99  ? 365 GLN C OE1 1 
ATOM   9577  N NE2 . GLN C 1 365 ? -1.610  -40.380 27.245  1.00 57.18  ? 365 GLN C NE2 1 
ATOM   9578  N N   . LEU C 1 366 ? -2.644  -39.134 32.797  1.00 54.08  ? 366 LEU C N   1 
ATOM   9579  C CA  . LEU C 1 366 ? -2.862  -37.878 33.530  1.00 49.81  ? 366 LEU C CA  1 
ATOM   9580  C C   . LEU C 1 366 ? -1.525  -37.274 33.920  1.00 45.48  ? 366 LEU C C   1 
ATOM   9581  O O   . LEU C 1 366 ? -0.910  -37.717 34.877  1.00 49.49  ? 366 LEU C O   1 
ATOM   9582  C CB  . LEU C 1 366 ? -3.723  -38.081 34.772  1.00 46.83  ? 366 LEU C CB  1 
ATOM   9583  C CG  . LEU C 1 366 ? -5.191  -38.421 34.530  1.00 51.91  ? 366 LEU C CG  1 
ATOM   9584  C CD1 . LEU C 1 366 ? -5.892  -38.498 35.862  1.00 49.83  ? 366 LEU C CD1 1 
ATOM   9585  C CD2 . LEU C 1 366 ? -5.895  -37.423 33.590  1.00 57.27  ? 366 LEU C CD2 1 
ATOM   9586  N N   . LEU C 1 367 ? -1.128  -36.217 33.211  1.00 42.54  ? 367 LEU C N   1 
ATOM   9587  C CA  . LEU C 1 367 ? 0.097   -35.495 33.505  1.00 45.43  ? 367 LEU C CA  1 
ATOM   9588  C C   . LEU C 1 367 ? -0.257  -34.153 34.148  1.00 48.16  ? 367 LEU C C   1 
ATOM   9589  O O   . LEU C 1 367 ? -0.839  -33.292 33.509  1.00 48.91  ? 367 LEU C O   1 
ATOM   9590  C CB  . LEU C 1 367 ? 0.898   -35.296 32.222  1.00 40.08  ? 367 LEU C CB  1 
ATOM   9591  C CG  . LEU C 1 367 ? 2.188   -34.498 32.370  1.00 40.95  ? 367 LEU C CG  1 
ATOM   9592  C CD1 . LEU C 1 367 ? 3.255   -35.368 33.042  1.00 47.57  ? 367 LEU C CD1 1 
ATOM   9593  C CD2 . LEU C 1 367 ? 2.696   -33.928 31.044  1.00 38.02  ? 367 LEU C CD2 1 
ATOM   9594  N N   . ALA C 1 368 ? 0.158   -33.987 35.400  1.00 53.34  ? 368 ALA C N   1 
ATOM   9595  C CA  . ALA C 1 368 ? -0.162  -32.808 36.173  1.00 52.05  ? 368 ALA C CA  1 
ATOM   9596  C C   . ALA C 1 368 ? 0.716   -31.655 35.717  1.00 47.35  ? 368 ALA C C   1 
ATOM   9597  O O   . ALA C 1 368 ? 1.729   -31.864 35.047  1.00 44.88  ? 368 ALA C O   1 
ATOM   9598  C CB  . ALA C 1 368 ? 0.024   -33.102 37.656  1.00 52.14  ? 368 ALA C CB  1 
ATOM   9599  N N   . PRO C 1 369 ? 0.350   -30.410 36.054  1.00 42.58  ? 369 PRO C N   1 
ATOM   9600  C CA  . PRO C 1 369 ? 1.141   -29.249 35.667  1.00 42.59  ? 369 PRO C CA  1 
ATOM   9601  C C   . PRO C 1 369 ? 2.557   -29.281 36.201  1.00 46.08  ? 369 PRO C C   1 
ATOM   9602  O O   . PRO C 1 369 ? 2.787   -29.742 37.314  1.00 59.40  ? 369 PRO C O   1 
ATOM   9603  C CB  . PRO C 1 369 ? 0.336   -28.103 36.259  1.00 43.22  ? 369 PRO C CB  1 
ATOM   9604  C CG  . PRO C 1 369 ? -1.064  -28.629 36.285  1.00 45.18  ? 369 PRO C CG  1 
ATOM   9605  C CD  . PRO C 1 369 ? -0.907  -30.053 36.698  1.00 41.06  ? 369 PRO C CD  1 
ATOM   9606  N N   . HIS C 1 370 ? 3.487   -28.720 35.414  1.00 47.00  ? 370 HIS C N   1 
ATOM   9607  C CA  . HIS C 1 370 ? 4.875   -28.572 35.815  1.00 47.86  ? 370 HIS C CA  1 
ATOM   9608  C C   . HIS C 1 370 ? 5.348   -27.168 35.468  1.00 47.01  ? 370 HIS C C   1 
ATOM   9609  O O   . HIS C 1 370 ? 5.273   -26.760 34.310  1.00 46.31  ? 370 HIS C O   1 
ATOM   9610  C CB  . HIS C 1 370 ? 5.772   -29.597 35.103  1.00 52.40  ? 370 HIS C CB  1 
ATOM   9611  C CG  . HIS C 1 370 ? 5.591   -30.999 35.552  1.00 48.57  ? 370 HIS C CG  1 
ATOM   9612  N ND1 . HIS C 1 370 ? 4.424   -31.699 35.324  1.00 51.55  ? 370 HIS C ND1 1 
ATOM   9613  C CD2 . HIS C 1 370 ? 6.419   -31.839 36.209  1.00 45.89  ? 370 HIS C CD2 1 
ATOM   9614  C CE1 . HIS C 1 370 ? 4.543   -32.929 35.838  1.00 56.09  ? 370 HIS C CE1 1 
ATOM   9615  N NE2 . HIS C 1 370 ? 5.746   -33.029 36.396  1.00 46.97  ? 370 HIS C NE2 1 
ATOM   9616  N N   . VAL C 1 371 ? 5.895   -26.459 36.472  1.00 49.76  ? 371 VAL C N   1 
ATOM   9617  C CA  . VAL C 1 371 ? 6.325   -25.077 36.295  1.00 52.81  ? 371 VAL C CA  1 
ATOM   9618  C C   . VAL C 1 371 ? 7.785   -24.967 36.695  1.00 48.59  ? 371 VAL C C   1 
ATOM   9619  O O   . VAL C 1 371 ? 8.176   -25.454 37.751  1.00 53.93  ? 371 VAL C O   1 
ATOM   9620  C CB  . VAL C 1 371 ? 5.464   -24.084 37.102  1.00 51.01  ? 371 VAL C CB  1 
ATOM   9621  C CG1 . VAL C 1 371 ? 5.869   -22.641 36.824  1.00 55.67  ? 371 VAL C CG1 1 
ATOM   9622  C CG2 . VAL C 1 371 ? 3.968   -24.286 36.847  1.00 47.63  ? 371 VAL C CG2 1 
ATOM   9623  N N   . PHE C 1 372 ? 8.572   -24.310 35.836  1.00 47.73  ? 372 PHE C N   1 
ATOM   9624  C CA  . PHE C 1 372 ? 9.986   -24.097 36.068  1.00 46.72  ? 372 PHE C CA  1 
ATOM   9625  C C   . PHE C 1 372 ? 10.280  -22.600 36.058  1.00 52.37  ? 372 PHE C C   1 
ATOM   9626  O O   . PHE C 1 372 ? 9.586   -21.838 35.391  1.00 44.95  ? 372 PHE C O   1 
ATOM   9627  C CB  . PHE C 1 372 ? 10.823  -24.800 35.002  1.00 53.01  ? 372 PHE C CB  1 
ATOM   9628  C CG  . PHE C 1 372 ? 10.900  -26.306 35.184  1.00 60.88  ? 372 PHE C CG  1 
ATOM   9629  C CD1 . PHE C 1 372 ? 9.930   -27.142 34.636  1.00 58.59  ? 372 PHE C CD1 1 
ATOM   9630  C CD2 . PHE C 1 372 ? 11.913  -26.883 35.953  1.00 63.72  ? 372 PHE C CD2 1 
ATOM   9631  C CE1 . PHE C 1 372 ? 9.989   -28.522 34.827  1.00 62.08  ? 372 PHE C CE1 1 
ATOM   9632  C CE2 . PHE C 1 372 ? 11.966  -28.266 36.135  1.00 66.71  ? 372 PHE C CE2 1 
ATOM   9633  C CZ  . PHE C 1 372 ? 11.014  -29.079 35.565  1.00 63.60  ? 372 PHE C CZ  1 
ATOM   9634  N N   . GLY C 1 373 ? 11.375  -22.213 36.756  1.00 57.31  ? 373 GLY C N   1 
ATOM   9635  C CA  . GLY C 1 373 ? 11.720  -20.823 36.974  1.00 52.51  ? 373 GLY C CA  1 
ATOM   9636  C C   . GLY C 1 373 ? 13.163  -20.521 36.570  1.00 53.46  ? 373 GLY C C   1 
ATOM   9637  O O   . GLY C 1 373 ? 13.949  -21.423 36.286  1.00 55.17  ? 373 GLY C O   1 
ATOM   9638  N N   . GLU C 1 374 ? 13.474  -19.226 36.528  1.00 49.21  ? 374 GLU C N   1 
ATOM   9639  C CA  . GLU C 1 374 ? 14.804  -18.729 36.239  1.00 50.84  ? 374 GLU C CA  1 
ATOM   9640  C C   . GLU C 1 374 ? 15.307  -19.281 34.902  1.00 60.37  ? 374 GLU C C   1 
ATOM   9641  O O   . GLU C 1 374 ? 16.506  -19.405 34.707  1.00 67.20  ? 374 GLU C O   1 
ATOM   9642  C CB  . GLU C 1 374 ? 15.753  -19.082 37.389  1.00 54.57  ? 374 GLU C CB  1 
ATOM   9643  C CG  . GLU C 1 374 ? 15.307  -18.527 38.751  1.00 56.47  ? 374 GLU C CG  1 
ATOM   9644  C CD  . GLU C 1 374 ? 15.366  -16.995 38.859  1.00 55.82  ? 374 GLU C CD  1 
ATOM   9645  O OE1 . GLU C 1 374 ? 16.061  -16.355 38.021  1.00 53.15  ? 374 GLU C OE1 1 
ATOM   9646  O OE2 . GLU C 1 374 ? 14.685  -16.444 39.749  1.00 49.26  ? 374 GLU C OE2 1 
ATOM   9647  N N   . VAL C 1 375 ? 14.394  -19.511 33.951  1.00 59.09  ? 375 VAL C N   1 
ATOM   9648  C CA  . VAL C 1 375 ? 14.766  -20.137 32.696  1.00 60.55  ? 375 VAL C CA  1 
ATOM   9649  C C   . VAL C 1 375 ? 15.367  -19.068 31.791  1.00 57.91  ? 375 VAL C C   1 
ATOM   9650  O O   . VAL C 1 375 ? 15.083  -17.880 31.968  1.00 57.03  ? 375 VAL C O   1 
ATOM   9651  C CB  . VAL C 1 375 ? 13.577  -20.867 32.028  1.00 59.46  ? 375 VAL C CB  1 
ATOM   9652  C CG1 . VAL C 1 375 ? 12.797  -21.708 33.029  1.00 56.53  ? 375 VAL C CG1 1 
ATOM   9653  C CG2 . VAL C 1 375 ? 12.654  -19.922 31.318  1.00 68.81  ? 375 VAL C CG2 1 
ATOM   9654  N N   . THR C 1 376 ? 16.242  -19.500 30.851  1.00 55.72  ? 376 THR C N   1 
ATOM   9655  C CA  . THR C 1 376 ? 16.945  -18.572 29.965  1.00 63.75  ? 376 THR C CA  1 
ATOM   9656  C C   . THR C 1 376 ? 16.586  -18.868 28.504  1.00 64.39  ? 376 THR C C   1 
ATOM   9657  O O   . THR C 1 376 ? 16.070  -19.936 28.188  1.00 66.39  ? 376 THR C O   1 
ATOM   9658  C CB  . THR C 1 376 ? 18.460  -18.659 30.194  1.00 67.70  ? 376 THR C CB  1 
ATOM   9659  O OG1 . THR C 1 376 ? 18.976  -17.394 29.801  1.00 69.58  ? 376 THR C OG1 1 
ATOM   9660  C CG2 . THR C 1 376 ? 19.134  -19.723 29.350  1.00 67.63  ? 376 THR C CG2 1 
ATOM   9661  N N   . ALA C 1 377 ? 16.969  -17.932 27.614  1.00 61.97  ? 377 ALA C N   1 
ATOM   9662  C CA  . ALA C 1 377 ? 16.560  -17.947 26.215  1.00 67.27  ? 377 ALA C CA  1 
ATOM   9663  C C   . ALA C 1 377 ? 17.152  -19.160 25.478  1.00 75.71  ? 377 ALA C C   1 
ATOM   9664  O O   . ALA C 1 377 ? 16.508  -19.718 24.589  1.00 82.85  ? 377 ALA C O   1 
ATOM   9665  C CB  . ALA C 1 377 ? 16.972  -16.644 25.554  1.00 65.10  ? 377 ALA C CB  1 
ATOM   9666  N N   . THR C 1 378 ? 18.382  -19.554 25.850  1.00 71.64  ? 378 THR C N   1 
ATOM   9667  C CA  . THR C 1 378 ? 19.106  -20.603 25.132  1.00 67.96  ? 378 THR C CA  1 
ATOM   9668  C C   . THR C 1 378 ? 18.524  -21.980 25.490  1.00 72.07  ? 378 THR C C   1 
ATOM   9669  O O   . THR C 1 378 ? 18.692  -22.925 24.733  1.00 78.39  ? 378 THR C O   1 
ATOM   9670  C CB  . THR C 1 378 ? 20.610  -20.540 25.439  1.00 63.73  ? 378 THR C CB  1 
ATOM   9671  O OG1 . THR C 1 378 ? 20.823  -21.272 26.646  1.00 60.00  ? 378 THR C OG1 1 
ATOM   9672  C CG2 . THR C 1 378 ? 21.120  -19.123 25.602  1.00 69.58  ? 378 THR C CG2 1 
ATOM   9673  N N   . MET C 1 379 ? 17.862  -22.091 26.655  1.00 71.69  ? 379 MET C N   1 
ATOM   9674  C CA  . MET C 1 379 ? 17.367  -23.383 27.139  1.00 68.08  ? 379 MET C CA  1 
ATOM   9675  C C   . MET C 1 379 ? 16.250  -23.891 26.219  1.00 70.06  ? 379 MET C C   1 
ATOM   9676  O O   . MET C 1 379 ? 15.512  -23.103 25.623  1.00 75.97  ? 379 MET C O   1 
ATOM   9677  C CB  . MET C 1 379 ? 16.838  -23.268 28.575  1.00 70.51  ? 379 MET C CB  1 
ATOM   9678  C CG  . MET C 1 379 ? 17.892  -22.887 29.592  1.00 72.56  ? 379 MET C CG  1 
ATOM   9679  S SD  . MET C 1 379 ? 17.211  -22.306 31.164  1.00 69.64  ? 379 MET C SD  1 
ATOM   9680  C CE  . MET C 1 379 ? 16.557  -23.851 31.790  1.00 61.26  ? 379 MET C CE  1 
ATOM   9681  N N   . GLU C 1 380 ? 16.100  -25.213 26.155  1.00 71.92  ? 380 GLU C N   1 
ATOM   9682  C CA  . GLU C 1 380 ? 15.167  -25.836 25.219  1.00 74.64  ? 380 GLU C CA  1 
ATOM   9683  C C   . GLU C 1 380 ? 13.712  -25.492 25.597  1.00 68.88  ? 380 GLU C C   1 
ATOM   9684  O O   . GLU C 1 380 ? 12.871  -25.289 24.717  1.00 62.36  ? 380 GLU C O   1 
ATOM   9685  C CB  . GLU C 1 380 ? 15.418  -27.346 25.168  1.00 78.85  ? 380 GLU C CB  1 
ATOM   9686  C CG  . GLU C 1 380 ? 14.673  -28.060 24.037  1.00 80.84  ? 380 GLU C CG  1 
ATOM   9687  C CD  . GLU C 1 380 ? 13.370  -28.734 24.464  1.00 87.42  ? 380 GLU C CD  1 
ATOM   9688  O OE1 . GLU C 1 380 ? 12.951  -28.586 25.661  1.00 86.45  ? 380 GLU C OE1 1 
ATOM   9689  O OE2 . GLU C 1 380 ? 12.772  -29.412 23.596  1.00 85.99  ? 380 GLU C OE2 1 
ATOM   9690  N N   . ILE C 1 381 ? 13.426  -25.415 26.899  1.00 61.30  ? 381 ILE C N   1 
ATOM   9691  C CA  . ILE C 1 381 ? 12.077  -25.084 27.369  1.00 58.62  ? 381 ILE C CA  1 
ATOM   9692  C C   . ILE C 1 381 ? 11.624  -23.686 26.830  1.00 60.38  ? 381 ILE C C   1 
ATOM   9693  O O   . ILE C 1 381 ? 10.434  -23.456 26.621  1.00 57.56  ? 381 ILE C O   1 
ATOM   9694  C CB  . ILE C 1 381 ? 12.006  -25.168 28.902  1.00 53.50  ? 381 ILE C CB  1 
ATOM   9695  C CG1 . ILE C 1 381 ? 10.606  -25.406 29.367  1.00 56.93  ? 381 ILE C CG1 1 
ATOM   9696  C CG2 . ILE C 1 381 ? 12.619  -23.931 29.550  1.00 60.63  ? 381 ILE C CG2 1 
ATOM   9697  C CD1 . ILE C 1 381 ? 10.445  -25.450 30.879  1.00 62.28  ? 381 ILE C CD1 1 
ATOM   9698  N N   . ALA C 1 382 ? 12.576  -22.775 26.579  1.00 55.51  ? 382 ALA C N   1 
ATOM   9699  C CA  . ALA C 1 382 ? 12.248  -21.468 26.005  1.00 56.12  ? 382 ALA C CA  1 
ATOM   9700  C C   . ALA C 1 382 ? 12.124  -21.551 24.475  1.00 60.51  ? 382 ALA C C   1 
ATOM   9701  O O   . ALA C 1 382 ? 11.257  -20.918 23.900  1.00 57.42  ? 382 ALA C O   1 
ATOM   9702  C CB  . ALA C 1 382 ? 13.285  -20.421 26.413  1.00 52.19  ? 382 ALA C CB  1 
ATOM   9703  N N   . ARG C 1 383 ? 13.047  -22.266 23.814  1.00 68.92  ? 383 ARG C N   1 
ATOM   9704  C CA  . ARG C 1 383 ? 13.190  -22.154 22.353  1.00 69.28  ? 383 ARG C CA  1 
ATOM   9705  C C   . ARG C 1 383 ? 12.062  -22.918 21.638  1.00 66.26  ? 383 ARG C C   1 
ATOM   9706  O O   . ARG C 1 383 ? 11.533  -22.435 20.652  1.00 54.62  ? 383 ARG C O   1 
ATOM   9707  C CB  . ARG C 1 383 ? 14.503  -22.708 21.812  1.00 78.08  ? 383 ARG C CB  1 
ATOM   9708  C CG  . ARG C 1 383 ? 15.783  -22.233 22.475  1.00 86.45  ? 383 ARG C CG  1 
ATOM   9709  C CD  . ARG C 1 383 ? 16.964  -22.814 21.701  1.00 92.61  ? 383 ARG C CD  1 
ATOM   9710  N NE  . ARG C 1 383 ? 16.832  -22.566 20.263  1.00 108.98 ? 383 ARG C NE  1 
ATOM   9711  C CZ  . ARG C 1 383 ? 16.832  -23.501 19.310  1.00 125.03 ? 383 ARG C CZ  1 
ATOM   9712  N NH1 . ARG C 1 383 ? 16.902  -24.787 19.627  1.00 131.93 ? 383 ARG C NH1 1 
ATOM   9713  N NH2 . ARG C 1 383 ? 16.749  -23.144 18.040  1.00 136.91 ? 383 ARG C NH2 1 
ATOM   9714  N N   . ASP C 1 384 ? 11.749  -24.145 22.121  1.00 66.33  ? 384 ASP C N   1 
ATOM   9715  C CA  . ASP C 1 384 ? 10.868  -25.068 21.411  1.00 71.50  ? 384 ASP C CA  1 
ATOM   9716  C C   . ASP C 1 384 ? 9.448   -24.976 21.964  1.00 74.30  ? 384 ASP C C   1 
ATOM   9717  O O   . ASP C 1 384 ? 9.249   -24.764 23.159  1.00 82.52  ? 384 ASP C O   1 
ATOM   9718  C CB  . ASP C 1 384 ? 11.371  -26.500 21.498  1.00 80.79  ? 384 ASP C CB  1 
ATOM   9719  C CG  . ASP C 1 384 ? 12.590  -26.816 20.645  1.00 94.85  ? 384 ASP C CG  1 
ATOM   9720  O OD1 . ASP C 1 384 ? 13.594  -26.091 20.769  1.00 110.32 ? 384 ASP C OD1 1 
ATOM   9721  O OD2 . ASP C 1 384 ? 12.526  -27.789 19.869  1.00 100.24 ? 384 ASP C OD2 1 
ATOM   9722  N N   . GLU C 1 385 ? 8.471   -25.226 21.085  1.00 72.10  ? 385 GLU C N   1 
ATOM   9723  C CA  . GLU C 1 385 ? 7.065   -25.250 21.454  1.00 80.69  ? 385 GLU C CA  1 
ATOM   9724  C C   . GLU C 1 385 ? 6.762   -26.515 22.251  1.00 75.20  ? 385 GLU C C   1 
ATOM   9725  O O   . GLU C 1 385 ? 7.287   -27.583 21.936  1.00 62.25  ? 385 GLU C O   1 
ATOM   9726  C CB  . GLU C 1 385 ? 6.202   -25.210 20.195  1.00 89.43  ? 385 GLU C CB  1 
ATOM   9727  C CG  . GLU C 1 385 ? 6.414   -26.415 19.281  1.00 86.09  ? 385 GLU C CG  1 
ATOM   9728  C CD  . GLU C 1 385 ? 6.336   -26.080 17.817  1.00 86.46  ? 385 GLU C CD  1 
ATOM   9729  O OE1 . GLU C 1 385 ? 7.149   -25.244 17.388  1.00 90.75  ? 385 GLU C OE1 1 
ATOM   9730  O OE2 . GLU C 1 385 ? 5.461   -26.629 17.113  1.00 87.41  ? 385 GLU C OE2 1 
ATOM   9731  N N   . ILE C 1 386 ? 5.904   -26.372 23.291  1.00 74.55  ? 386 ILE C N   1 
ATOM   9732  C CA  . ILE C 1 386 ? 5.365   -27.513 24.022  1.00 78.60  ? 386 ILE C CA  1 
ATOM   9733  C C   . ILE C 1 386 ? 3.846   -27.503 23.889  1.00 72.88  ? 386 ILE C C   1 
ATOM   9734  O O   . ILE C 1 386 ? 3.201   -26.454 24.039  1.00 86.64  ? 386 ILE C O   1 
ATOM   9735  C CB  . ILE C 1 386 ? 5.815   -27.521 25.506  1.00 85.43  ? 386 ILE C CB  1 
ATOM   9736  C CG1 . ILE C 1 386 ? 7.361   -27.532 25.645  1.00 94.10  ? 386 ILE C CG1 1 
ATOM   9737  C CG2 . ILE C 1 386 ? 5.184   -28.695 26.259  1.00 86.86  ? 386 ILE C CG2 1 
ATOM   9738  C CD1 . ILE C 1 386 ? 7.973   -26.204 26.060  1.00 95.07  ? 386 ILE C CD1 1 
ATOM   9739  N N   . PHE C 1 387 ? 3.294   -28.678 23.573  1.00 63.28  ? 387 PHE C N   1 
ATOM   9740  C CA  . PHE C 1 387 ? 1.856   -28.884 23.518  1.00 60.19  ? 387 PHE C CA  1 
ATOM   9741  C C   . PHE C 1 387 ? 1.438   -29.696 24.738  1.00 56.07  ? 387 PHE C C   1 
ATOM   9742  O O   . PHE C 1 387 ? 1.157   -30.877 24.625  1.00 54.79  ? 387 PHE C O   1 
ATOM   9743  C CB  . PHE C 1 387 ? 1.487   -29.605 22.216  1.00 65.59  ? 387 PHE C CB  1 
ATOM   9744  C CG  . PHE C 1 387 ? 0.978   -28.721 21.086  1.00 85.92  ? 387 PHE C CG  1 
ATOM   9745  C CD1 . PHE C 1 387 ? -0.342  -28.841 20.626  1.00 102.24 ? 387 PHE C CD1 1 
ATOM   9746  C CD2 . PHE C 1 387 ? 1.810   -27.781 20.464  1.00 93.46  ? 387 PHE C CD2 1 
ATOM   9747  C CE1 . PHE C 1 387 ? -0.819  -28.034 19.586  1.00 94.41  ? 387 PHE C CE1 1 
ATOM   9748  C CE2 . PHE C 1 387 ? 1.328   -26.978 19.421  1.00 93.18  ? 387 PHE C CE2 1 
ATOM   9749  C CZ  . PHE C 1 387 ? 0.017   -27.108 18.987  1.00 93.21  ? 387 PHE C CZ  1 
ATOM   9750  N N   . GLY C 1 388 ? 1.437   -29.053 25.912  1.00 50.63  ? 388 GLY C N   1 
ATOM   9751  C CA  . GLY C 1 388 ? 0.996   -29.708 27.139  1.00 46.28  ? 388 GLY C CA  1 
ATOM   9752  C C   . GLY C 1 388 ? 1.219   -28.828 28.378  1.00 43.11  ? 388 GLY C C   1 
ATOM   9753  O O   . GLY C 1 388 ? 1.674   -27.698 28.262  1.00 39.81  ? 388 GLY C O   1 
ATOM   9754  N N   . PRO C 1 389 ? 0.906   -29.342 29.598  1.00 39.10  ? 389 PRO C N   1 
ATOM   9755  C CA  . PRO C 1 389 ? 0.950   -28.540 30.823  1.00 38.72  ? 389 PRO C CA  1 
ATOM   9756  C C   . PRO C 1 389 ? 2.349   -28.397 31.428  1.00 45.90  ? 389 PRO C C   1 
ATOM   9757  O O   . PRO C 1 389 ? 2.580   -28.757 32.594  1.00 44.39  ? 389 PRO C O   1 
ATOM   9758  C CB  . PRO C 1 389 ? -0.018  -29.310 31.735  1.00 41.38  ? 389 PRO C CB  1 
ATOM   9759  C CG  . PRO C 1 389 ? 0.153   -30.765 31.319  1.00 42.20  ? 389 PRO C CG  1 
ATOM   9760  C CD  . PRO C 1 389 ? 0.419   -30.702 29.828  1.00 40.86  ? 389 PRO C CD  1 
ATOM   9761  N N   . LEU C 1 390 ? 3.253   -27.803 30.631  1.00 42.79  ? 390 LEU C N   1 
ATOM   9762  C CA  . LEU C 1 390 ? 4.621   -27.531 31.021  1.00 43.22  ? 390 LEU C CA  1 
ATOM   9763  C C   . LEU C 1 390 ? 4.933   -26.083 30.617  1.00 47.22  ? 390 LEU C C   1 
ATOM   9764  O O   . LEU C 1 390 ? 4.749   -25.716 29.456  1.00 42.00  ? 390 LEU C O   1 
ATOM   9765  C CB  . LEU C 1 390 ? 5.496   -28.570 30.275  1.00 47.72  ? 390 LEU C CB  1 
ATOM   9766  C CG  . LEU C 1 390 ? 6.987   -28.692 30.649  1.00 57.29  ? 390 LEU C CG  1 
ATOM   9767  C CD1 . LEU C 1 390 ? 7.841   -27.639 29.969  1.00 63.96  ? 390 LEU C CD1 1 
ATOM   9768  C CD2 . LEU C 1 390 ? 7.224   -28.662 32.158  1.00 58.88  ? 390 LEU C CD2 1 
ATOM   9769  N N   . VAL C 1 391 ? 5.392   -25.255 31.580  1.00 45.52  ? 391 VAL C N   1 
ATOM   9770  C CA  . VAL C 1 391 ? 5.626   -23.841 31.311  1.00 42.07  ? 391 VAL C CA  1 
ATOM   9771  C C   . VAL C 1 391 ? 6.903   -23.385 32.027  1.00 42.57  ? 391 VAL C C   1 
ATOM   9772  O O   . VAL C 1 391 ? 7.246   -23.893 33.089  1.00 43.18  ? 391 VAL C O   1 
ATOM   9773  C CB  . VAL C 1 391 ? 4.407   -22.988 31.736  1.00 43.71  ? 391 VAL C CB  1 
ATOM   9774  C CG1 . VAL C 1 391 ? 4.194   -23.016 33.272  1.00 45.43  ? 391 VAL C CG1 1 
ATOM   9775  C CG2 . VAL C 1 391 ? 4.517   -21.550 31.228  1.00 40.91  ? 391 VAL C CG2 1 
ATOM   9776  N N   . GLY C 1 392 ? 7.562   -22.374 31.453  1.00 43.81  ? 392 GLY C N   1 
ATOM   9777  C CA  . GLY C 1 392 ? 8.763   -21.799 32.026  1.00 48.96  ? 392 GLY C CA  1 
ATOM   9778  C C   . GLY C 1 392 ? 8.606   -20.286 32.278  1.00 53.99  ? 392 GLY C C   1 
ATOM   9779  O O   . GLY C 1 392 ? 7.968   -19.577 31.486  1.00 51.78  ? 392 GLY C O   1 
ATOM   9780  N N   . LEU C 1 393 ? 9.196   -19.811 33.404  1.00 50.99  ? 393 LEU C N   1 
ATOM   9781  C CA  . LEU C 1 393 ? 9.093   -18.419 33.834  1.00 44.64  ? 393 LEU C CA  1 
ATOM   9782  C C   . LEU C 1 393 ? 10.462  -17.755 33.676  1.00 46.03  ? 393 LEU C C   1 
ATOM   9783  O O   . LEU C 1 393 ? 11.453  -18.252 34.186  1.00 44.92  ? 393 LEU C O   1 
ATOM   9784  C CB  . LEU C 1 393 ? 8.613   -18.336 35.285  1.00 42.63  ? 393 LEU C CB  1 
ATOM   9785  C CG  . LEU C 1 393 ? 7.093   -18.281 35.528  1.00 47.66  ? 393 LEU C CG  1 
ATOM   9786  C CD1 . LEU C 1 393 ? 6.318   -19.347 34.813  1.00 52.48  ? 393 LEU C CD1 1 
ATOM   9787  C CD2 . LEU C 1 393 ? 6.821   -18.381 37.016  1.00 48.65  ? 393 LEU C CD2 1 
ATOM   9788  N N   . LEU C 1 394 ? 10.485  -16.610 32.981  1.00 42.13  ? 394 LEU C N   1 
ATOM   9789  C CA  . LEU C 1 394 ? 11.709  -15.916 32.661  1.00 44.95  ? 394 LEU C CA  1 
ATOM   9790  C C   . LEU C 1 394 ? 11.737  -14.606 33.428  1.00 47.85  ? 394 LEU C C   1 
ATOM   9791  O O   . LEU C 1 394 ? 10.732  -13.905 33.485  1.00 46.62  ? 394 LEU C O   1 
ATOM   9792  C CB  . LEU C 1 394 ? 11.842  -15.651 31.152  1.00 46.85  ? 394 LEU C CB  1 
ATOM   9793  C CG  . LEU C 1 394 ? 12.151  -16.859 30.246  1.00 46.42  ? 394 LEU C CG  1 
ATOM   9794  C CD1 . LEU C 1 394 ? 10.897  -17.578 29.804  1.00 46.04  ? 394 LEU C CD1 1 
ATOM   9795  C CD2 . LEU C 1 394 ? 12.952  -16.427 29.040  1.00 46.70  ? 394 LEU C CD2 1 
ATOM   9796  N N   . ARG C 1 395 ? 12.933  -14.252 33.938  1.00 51.08  ? 395 ARG C N   1 
ATOM   9797  C CA  . ARG C 1 395 ? 13.156  -13.005 34.654  1.00 47.85  ? 395 ARG C CA  1 
ATOM   9798  C C   . ARG C 1 395 ? 13.791  -12.006 33.714  1.00 43.14  ? 395 ARG C C   1 
ATOM   9799  O O   . ARG C 1 395 ? 14.837  -12.261 33.176  1.00 47.66  ? 395 ARG C O   1 
ATOM   9800  C CB  . ARG C 1 395 ? 14.064  -13.235 35.872  1.00 48.90  ? 395 ARG C CB  1 
ATOM   9801  C CG  . ARG C 1 395 ? 14.269  -12.005 36.755  1.00 55.30  ? 395 ARG C CG  1 
ATOM   9802  C CD  . ARG C 1 395 ? 15.317  -12.243 37.885  1.00 54.91  ? 395 ARG C CD  1 
ATOM   9803  N NE  . ARG C 1 395 ? 14.916  -13.287 38.842  1.00 50.84  ? 395 ARG C NE  1 
ATOM   9804  C CZ  . ARG C 1 395 ? 14.263  -13.062 39.980  1.00 47.73  ? 395 ARG C CZ  1 
ATOM   9805  N NH1 . ARG C 1 395 ? 13.888  -11.814 40.299  1.00 47.53  ? 395 ARG C NH1 1 
ATOM   9806  N NH2 . ARG C 1 395 ? 13.952  -14.086 40.780  1.00 41.02  ? 395 ARG C NH2 1 
ATOM   9807  N N   . ALA C 1 396 ? 13.147  -10.847 33.557  1.00 47.03  ? 396 ALA C N   1 
ATOM   9808  C CA  . ALA C 1 396 ? 13.655  -9.782  32.706  1.00 48.45  ? 396 ALA C CA  1 
ATOM   9809  C C   . ALA C 1 396 ? 14.096  -8.592  33.564  1.00 53.74  ? 396 ALA C C   1 
ATOM   9810  O O   . ALA C 1 396 ? 13.369  -8.154  34.446  1.00 59.63  ? 396 ALA C O   1 
ATOM   9811  C CB  . ALA C 1 396 ? 12.588  -9.374  31.719  1.00 47.55  ? 396 ALA C CB  1 
ATOM   9812  N N   . ARG C 1 397 ? 15.282  -8.058  33.276  1.00 62.89  ? 397 ARG C N   1 
ATOM   9813  C CA  . ARG C 1 397 ? 15.854  -7.005  34.106  1.00 65.22  ? 397 ARG C CA  1 
ATOM   9814  C C   . ARG C 1 397 ? 15.061  -5.718  33.896  1.00 62.14  ? 397 ARG C C   1 
ATOM   9815  O O   . ARG C 1 397 ? 14.683  -5.066  34.857  1.00 58.47  ? 397 ARG C O   1 
ATOM   9816  C CB  . ARG C 1 397 ? 17.362  -6.827  33.879  1.00 61.82  ? 397 ARG C CB  1 
ATOM   9817  C CG  . ARG C 1 397 ? 17.862  -7.069  32.465  1.00 61.91  ? 397 ARG C CG  1 
ATOM   9818  C CD  . ARG C 1 397 ? 19.406  -6.924  32.368  1.00 61.01  ? 397 ARG C CD  1 
ATOM   9819  N NE  . ARG C 1 397 ? 19.907  -7.247  31.019  1.00 62.64  ? 397 ARG C NE  1 
ATOM   9820  C CZ  . ARG C 1 397 ? 20.102  -8.494  30.543  1.00 65.02  ? 397 ARG C CZ  1 
ATOM   9821  N NH1 . ARG C 1 397 ? 20.028  -9.536  31.361  1.00 60.15  ? 397 ARG C NH1 1 
ATOM   9822  N NH2 . ARG C 1 397 ? 20.407  -8.683  29.257  1.00 68.05  ? 397 ARG C NH2 1 
ATOM   9823  N N   . ASP C 1 398 ? 14.752  -5.407  32.642  1.00 56.96  ? 398 ASP C N   1 
ATOM   9824  C CA  . ASP C 1 398 ? 14.005  -4.204  32.331  1.00 56.40  ? 398 ASP C CA  1 
ATOM   9825  C C   . ASP C 1 398 ? 13.063  -4.474  31.147  1.00 55.96  ? 398 ASP C C   1 
ATOM   9826  O O   . ASP C 1 398 ? 12.916  -5.613  30.706  1.00 61.25  ? 398 ASP C O   1 
ATOM   9827  C CB  . ASP C 1 398 ? 14.960  -3.050  32.109  1.00 58.55  ? 398 ASP C CB  1 
ATOM   9828  C CG  . ASP C 1 398 ? 16.093  -3.327  31.137  1.00 67.60  ? 398 ASP C CG  1 
ATOM   9829  O OD1 . ASP C 1 398 ? 17.093  -2.598  31.193  1.00 64.96  ? 398 ASP C OD1 1 
ATOM   9830  O OD2 . ASP C 1 398 ? 15.944  -4.255  30.300  1.00 87.09  ? 398 ASP C OD2 1 
ATOM   9831  N N   . GLU C 1 399 ? 12.427  -3.410  30.649  1.00 50.11  ? 399 GLU C N   1 
ATOM   9832  C CA  . GLU C 1 399 ? 11.525  -3.498  29.513  1.00 51.64  ? 399 GLU C CA  1 
ATOM   9833  C C   . GLU C 1 399 ? 12.296  -3.964  28.281  1.00 54.47  ? 399 GLU C C   1 
ATOM   9834  O O   . GLU C 1 399 ? 11.804  -4.803  27.510  1.00 52.83  ? 399 GLU C O   1 
ATOM   9835  C CB  . GLU C 1 399 ? 10.857  -2.142  29.260  1.00 47.91  ? 399 GLU C CB  1 
ATOM   9836  C CG  . GLU C 1 399 ? 9.669   -2.213  28.312  1.00 49.98  ? 399 GLU C CG  1 
ATOM   9837  C CD  . GLU C 1 399 ? 9.011   -0.864  28.037  1.00 52.75  ? 399 GLU C CD  1 
ATOM   9838  O OE1 . GLU C 1 399 ? 8.899   -0.060  28.982  1.00 51.00  ? 399 GLU C OE1 1 
ATOM   9839  O OE2 . GLU C 1 399 ? 8.587   -0.633  26.873  1.00 56.68  ? 399 GLU C OE2 1 
ATOM   9840  N N   . ALA C 1 400 ? 13.496  -3.398  28.092  1.00 55.39  ? 400 ALA C N   1 
ATOM   9841  C CA  . ALA C 1 400 ? 14.313  -3.691  26.919  1.00 54.48  ? 400 ALA C CA  1 
ATOM   9842  C C   . ALA C 1 400 ? 14.655  -5.183  26.873  1.00 49.42  ? 400 ALA C C   1 
ATOM   9843  O O   . ALA C 1 400 ? 14.613  -5.790  25.813  1.00 49.76  ? 400 ALA C O   1 
ATOM   9844  C CB  . ALA C 1 400 ? 15.561  -2.836  26.933  1.00 55.40  ? 400 ALA C CB  1 
ATOM   9845  N N   . HIS C 1 401 ? 14.969  -5.764  28.049  1.00 51.51  ? 401 HIS C N   1 
ATOM   9846  C CA  . HIS C 1 401 ? 15.312  -7.179  28.148  1.00 51.33  ? 401 HIS C CA  1 
ATOM   9847  C C   . HIS C 1 401 ? 14.077  -8.037  27.849  1.00 51.42  ? 401 HIS C C   1 
ATOM   9848  O O   . HIS C 1 401 ? 14.185  -9.065  27.185  1.00 57.24  ? 401 HIS C O   1 
ATOM   9849  C CB  . HIS C 1 401 ? 15.943  -7.505  29.523  1.00 50.84  ? 401 HIS C CB  1 
ATOM   9850  C CG  . HIS C 1 401 ? 16.533  -8.896  29.627  1.00 46.15  ? 401 HIS C CG  1 
ATOM   9851  N ND1 . HIS C 1 401 ? 16.623  -9.586  30.826  1.00 43.55  ? 401 HIS C ND1 1 
ATOM   9852  C CD2 . HIS C 1 401 ? 17.019  -9.735  28.680  1.00 45.52  ? 401 HIS C CD2 1 
ATOM   9853  C CE1 . HIS C 1 401 ? 17.140  -10.786 30.611  1.00 43.60  ? 401 HIS C CE1 1 
ATOM   9854  N NE2 . HIS C 1 401 ? 17.375  -10.908 29.309  1.00 46.98  ? 401 HIS C NE2 1 
ATOM   9855  N N   . ALA C 1 402 ? 12.910  -7.609  28.348  1.00 47.60  ? 402 ALA C N   1 
ATOM   9856  C CA  . ALA C 1 402 ? 11.664  -8.348  28.127  1.00 49.51  ? 402 ALA C CA  1 
ATOM   9857  C C   . ALA C 1 402 ? 11.355  -8.436  26.625  1.00 47.82  ? 402 ALA C C   1 
ATOM   9858  O O   . ALA C 1 402 ? 10.951  -9.480  26.137  1.00 38.32  ? 402 ALA C O   1 
ATOM   9859  C CB  . ALA C 1 402 ? 10.525  -7.702  28.886  1.00 46.42  ? 402 ALA C CB  1 
ATOM   9860  N N   . LEU C 1 403 ? 11.565  -7.328  25.907  1.00 48.17  ? 403 LEU C N   1 
ATOM   9861  C CA  . LEU C 1 403 ? 11.344  -7.301  24.477  1.00 49.71  ? 403 LEU C CA  1 
ATOM   9862  C C   . LEU C 1 403 ? 12.276  -8.308  23.783  1.00 60.85  ? 403 LEU C C   1 
ATOM   9863  O O   . LEU C 1 403 ? 11.836  -9.056  22.894  1.00 65.35  ? 403 LEU C O   1 
ATOM   9864  C CB  . LEU C 1 403 ? 11.556  -5.893  23.953  1.00 46.02  ? 403 LEU C CB  1 
ATOM   9865  C CG  . LEU C 1 403 ? 11.171  -5.675  22.496  1.00 50.82  ? 403 LEU C CG  1 
ATOM   9866  C CD1 . LEU C 1 403 ? 9.693   -6.061  22.258  1.00 53.23  ? 403 LEU C CD1 1 
ATOM   9867  C CD2 . LEU C 1 403 ? 11.432  -4.232  22.089  1.00 48.38  ? 403 LEU C CD2 1 
ATOM   9868  N N   . GLU C 1 404 ? 13.568  -8.298  24.176  1.00 62.17  ? 404 GLU C N   1 
ATOM   9869  C CA  . GLU C 1 404 ? 14.576  -9.170  23.577  1.00 64.37  ? 404 GLU C CA  1 
ATOM   9870  C C   . GLU C 1 404 ? 14.201  -10.647 23.791  1.00 57.66  ? 404 GLU C C   1 
ATOM   9871  O O   . GLU C 1 404 ? 14.302  -11.457 22.871  1.00 50.63  ? 404 GLU C O   1 
ATOM   9872  C CB  . GLU C 1 404 ? 15.956  -8.865  24.167  1.00 74.56  ? 404 GLU C CB  1 
ATOM   9873  C CG  . GLU C 1 404 ? 16.843  -10.111 24.309  1.00 79.99  ? 404 GLU C CG  1 
ATOM   9874  C CD  . GLU C 1 404 ? 18.208  -9.852  24.929  1.00 79.55  ? 404 GLU C CD  1 
ATOM   9875  O OE1 . GLU C 1 404 ? 18.677  -10.674 25.770  1.00 81.76  ? 404 GLU C OE1 1 
ATOM   9876  O OE2 . GLU C 1 404 ? 18.786  -8.809  24.593  1.00 69.22  ? 404 GLU C OE2 1 
ATOM   9877  N N   . LEU C 1 405 ? 13.809  -10.992 25.029  1.00 58.38  ? 405 LEU C N   1 
ATOM   9878  C CA  . LEU C 1 405 ? 13.496  -12.369 25.383  1.00 55.64  ? 405 LEU C CA  1 
ATOM   9879  C C   . LEU C 1 405 ? 12.283  -12.847 24.592  1.00 54.81  ? 405 LEU C C   1 
ATOM   9880  O O   . LEU C 1 405 ? 12.242  -13.997 24.174  1.00 53.98  ? 405 LEU C O   1 
ATOM   9881  C CB  . LEU C 1 405 ? 13.247  -12.475 26.877  1.00 58.00  ? 405 LEU C CB  1 
ATOM   9882  C CG  . LEU C 1 405 ? 14.466  -12.280 27.772  1.00 61.46  ? 405 LEU C CG  1 
ATOM   9883  C CD1 . LEU C 1 405 ? 14.045  -12.134 29.245  1.00 61.71  ? 405 LEU C CD1 1 
ATOM   9884  C CD2 . LEU C 1 405 ? 15.427  -13.451 27.590  1.00 60.94  ? 405 LEU C CD2 1 
ATOM   9885  N N   . ALA C 1 406 ? 11.262  -11.977 24.462  1.00 50.57  ? 406 ALA C N   1 
ATOM   9886  C CA  . ALA C 1 406 ? 10.022  -12.348 23.779  1.00 57.86  ? 406 ALA C CA  1 
ATOM   9887  C C   . ALA C 1 406 ? 10.292  -12.575 22.295  1.00 52.61  ? 406 ALA C C   1 
ATOM   9888  O O   . ALA C 1 406 ? 9.730   -13.471 21.704  1.00 49.45  ? 406 ALA C O   1 
ATOM   9889  C CB  . ALA C 1 406 ? 8.941   -11.278 23.985  1.00 59.87  ? 406 ALA C CB  1 
ATOM   9890  N N   . ASN C 1 407 ? 11.182  -11.757 21.715  1.00 51.50  ? 407 ASN C N   1 
ATOM   9891  C CA  . ASN C 1 407 ? 11.389  -11.733 20.272  1.00 51.48  ? 407 ASN C CA  1 
ATOM   9892  C C   . ASN C 1 407 ? 12.413  -12.805 19.829  1.00 56.16  ? 407 ASN C C   1 
ATOM   9893  O O   . ASN C 1 407 ? 12.617  -13.008 18.636  1.00 60.93  ? 407 ASN C O   1 
ATOM   9894  C CB  . ASN C 1 407 ? 11.797  -10.346 19.801  1.00 44.16  ? 407 ASN C CB  1 
ATOM   9895  C CG  . ASN C 1 407 ? 10.618  -9.535  19.314  1.00 49.58  ? 407 ASN C CG  1 
ATOM   9896  O OD1 . ASN C 1 407 ? 9.508   -10.065 19.153  1.00 47.40  ? 407 ASN C OD1 1 
ATOM   9897  N ND2 . ASN C 1 407 ? 10.828  -8.245  19.086  1.00 53.30  ? 407 ASN C ND2 1 
ATOM   9898  N N   . ALA C 1 408 ? 13.030  -13.499 20.782  1.00 59.20  ? 408 ALA C N   1 
ATOM   9899  C CA  . ALA C 1 408 ? 14.008  -14.542 20.462  1.00 66.80  ? 408 ALA C CA  1 
ATOM   9900  C C   . ALA C 1 408 ? 13.336  -15.730 19.758  1.00 73.41  ? 408 ALA C C   1 
ATOM   9901  O O   . ALA C 1 408 ? 13.994  -16.500 19.075  1.00 64.99  ? 408 ALA C O   1 
ATOM   9902  C CB  . ALA C 1 408 ? 14.711  -14.991 21.719  1.00 67.31  ? 408 ALA C CB  1 
ATOM   9903  N N   . SER C 1 409 ? 12.020  -15.866 19.939  1.00 85.08  ? 409 SER C N   1 
ATOM   9904  C CA  . SER C 1 409 ? 11.287  -17.034 19.470  1.00 92.82  ? 409 SER C CA  1 
ATOM   9905  C C   . SER C 1 409 ? 11.357  -17.148 17.950  1.00 99.46  ? 409 SER C C   1 
ATOM   9906  O O   . SER C 1 409 ? 11.086  -18.208 17.399  1.00 88.74  ? 409 SER C O   1 
ATOM   9907  C CB  . SER C 1 409 ? 9.837   -16.990 19.934  1.00 105.45 ? 409 SER C CB  1 
ATOM   9908  O OG  . SER C 1 409 ? 9.160   -15.829 19.445  1.00 102.38 ? 409 SER C OG  1 
ATOM   9909  N N   . GLU C 1 410 ? 11.640  -16.027 17.279  1.00 109.04 ? 410 GLU C N   1 
ATOM   9910  C CA  . GLU C 1 410 ? 11.370  -15.895 15.855  1.00 131.94 ? 410 GLU C CA  1 
ATOM   9911  C C   . GLU C 1 410 ? 9.868   -15.877 15.583  1.00 134.43 ? 410 GLU C C   1 
ATOM   9912  O O   . GLU C 1 410 ? 9.333   -14.871 15.135  1.00 126.33 ? 410 GLU C O   1 
ATOM   9913  C CB  . GLU C 1 410 ? 11.872  -17.057 15.010  1.00 151.70 ? 410 GLU C CB  1 
ATOM   9914  N N   . TYR C 1 411 ? 9.240   -17.054 15.700  1.00 145.93 ? 411 TYR C N   1 
ATOM   9915  C CA  . TYR C 1 411 ? 7.948   -17.296 15.094  1.00 151.13 ? 411 TYR C CA  1 
ATOM   9916  C C   . TYR C 1 411 ? 6.865   -16.802 16.050  1.00 144.62 ? 411 TYR C C   1 
ATOM   9917  O O   . TYR C 1 411 ? 6.779   -17.266 17.183  1.00 147.74 ? 411 TYR C O   1 
ATOM   9918  C CB  . TYR C 1 411 ? 7.762   -18.783 14.751  1.00 158.79 ? 411 TYR C CB  1 
ATOM   9919  N N   . GLY C 1 412 ? 6.068   -15.835 15.594  1.00 120.02 ? 412 GLY C N   1 
ATOM   9920  C CA  . GLY C 1 412 ? 5.091   -15.192 16.455  1.00 110.63 ? 412 GLY C CA  1 
ATOM   9921  C C   . GLY C 1 412 ? 3.689   -15.257 15.863  1.00 100.62 ? 412 GLY C C   1 
ATOM   9922  O O   . GLY C 1 412 ? 3.277   -14.366 15.117  1.00 90.72  ? 412 GLY C O   1 
ATOM   9923  N N   . LEU C 1 413 ? 2.934   -16.286 16.240  1.00 83.40  ? 413 LEU C N   1 
ATOM   9924  C CA  . LEU C 1 413 ? 1.537   -16.345 15.866  1.00 80.96  ? 413 LEU C CA  1 
ATOM   9925  C C   . LEU C 1 413 ? 0.718   -15.441 16.792  1.00 77.30  ? 413 LEU C C   1 
ATOM   9926  O O   . LEU C 1 413 ? -0.030  -14.591 16.318  1.00 75.66  ? 413 LEU C O   1 
ATOM   9927  C CB  . LEU C 1 413 ? 1.016   -17.774 15.869  1.00 85.90  ? 413 LEU C CB  1 
ATOM   9928  C CG  . LEU C 1 413 ? -0.118  -18.046 14.880  1.00 92.99  ? 413 LEU C CG  1 
ATOM   9929  C CD1 . LEU C 1 413 ? 0.306   -17.657 13.470  1.00 93.66  ? 413 LEU C CD1 1 
ATOM   9930  C CD2 . LEU C 1 413 ? -0.553  -19.483 14.923  1.00 104.39 ? 413 LEU C CD2 1 
ATOM   9931  N N   . SER C 1 414 ? 0.857   -15.646 18.114  1.00 66.20  ? 414 SER C N   1 
ATOM   9932  C CA  . SER C 1 414 ? 0.143   -14.843 19.094  1.00 61.20  ? 414 SER C CA  1 
ATOM   9933  C C   . SER C 1 414 ? 1.096   -14.413 20.205  1.00 55.34  ? 414 SER C C   1 
ATOM   9934  O O   . SER C 1 414 ? 2.188   -14.957 20.340  1.00 50.07  ? 414 SER C O   1 
ATOM   9935  C CB  . SER C 1 414 ? -1.044  -15.584 19.657  1.00 61.97  ? 414 SER C CB  1 
ATOM   9936  O OG  . SER C 1 414 ? -1.877  -14.713 20.403  1.00 71.83  ? 414 SER C OG  1 
ATOM   9937  N N   . SER C 1 415 ? 0.641   -13.440 20.998  1.00 49.92  ? 415 SER C N   1 
ATOM   9938  C CA  . SER C 1 415 ? 1.413   -12.863 22.083  1.00 42.86  ? 415 SER C CA  1 
ATOM   9939  C C   . SER C 1 415 ? 0.470   -12.149 23.030  1.00 44.02  ? 415 SER C C   1 
ATOM   9940  O O   . SER C 1 415 ? -0.689  -11.912 22.686  1.00 43.81  ? 415 SER C O   1 
ATOM   9941  C CB  . SER C 1 415 ? 2.449   -11.928 21.576  1.00 41.15  ? 415 SER C CB  1 
ATOM   9942  O OG  . SER C 1 415 ? 1.875   -10.977 20.681  1.00 43.09  ? 415 SER C OG  1 
ATOM   9943  N N   . ALA C 1 416 ? 0.980   -11.830 24.241  1.00 45.31  ? 416 ALA C N   1 
ATOM   9944  C CA  . ALA C 1 416 ? 0.229   -11.084 25.242  1.00 38.89  ? 416 ALA C CA  1 
ATOM   9945  C C   . ALA C 1 416 ? 1.181   -10.212 26.046  1.00 38.51  ? 416 ALA C C   1 
ATOM   9946  O O   . ALA C 1 416 ? 2.353   -10.576 26.254  1.00 38.46  ? 416 ALA C O   1 
ATOM   9947  C CB  . ALA C 1 416 ? -0.538  -12.028 26.127  1.00 39.55  ? 416 ALA C CB  1 
ATOM   9948  N N   . VAL C 1 417 ? 0.681   -9.044  26.456  1.00 35.19  ? 417 VAL C N   1 
ATOM   9949  C CA  . VAL C 1 417 ? 1.435   -8.122  27.282  1.00 38.51  ? 417 VAL C CA  1 
ATOM   9950  C C   . VAL C 1 417 ? 0.486   -7.523  28.332  1.00 38.34  ? 417 VAL C C   1 
ATOM   9951  O O   . VAL C 1 417 ? -0.637  -7.142  28.015  1.00 38.45  ? 417 VAL C O   1 
ATOM   9952  C CB  . VAL C 1 417 ? 2.130   -7.025  26.443  1.00 38.91  ? 417 VAL C CB  1 
ATOM   9953  C CG1 . VAL C 1 417 ? 1.180   -6.327  25.513  1.00 44.58  ? 417 VAL C CG1 1 
ATOM   9954  C CG2 . VAL C 1 417 ? 2.822   -6.007  27.321  1.00 46.34  ? 417 VAL C CG2 1 
ATOM   9955  N N   . PHE C 1 418 ? 0.959   -7.442  29.590  1.00 40.68  ? 418 PHE C N   1 
ATOM   9956  C CA  . PHE C 1 418 ? 0.152   -6.932  30.702  1.00 36.12  ? 418 PHE C CA  1 
ATOM   9957  C C   . PHE C 1 418 ? 0.829   -5.705  31.312  1.00 36.49  ? 418 PHE C C   1 
ATOM   9958  O O   . PHE C 1 418 ? 1.956   -5.782  31.768  1.00 37.66  ? 418 PHE C O   1 
ATOM   9959  C CB  . PHE C 1 418 ? -0.058  -8.018  31.744  1.00 35.25  ? 418 PHE C CB  1 
ATOM   9960  C CG  . PHE C 1 418 ? -1.214  -8.948  31.442  1.00 38.16  ? 418 PHE C CG  1 
ATOM   9961  C CD1 . PHE C 1 418 ? -1.093  -9.956  30.491  1.00 41.52  ? 418 PHE C CD1 1 
ATOM   9962  C CD2 . PHE C 1 418 ? -2.424  -8.821  32.113  1.00 41.06  ? 418 PHE C CD2 1 
ATOM   9963  C CE1 . PHE C 1 418 ? -2.162  -10.819 30.219  1.00 40.27  ? 418 PHE C CE1 1 
ATOM   9964  C CE2 . PHE C 1 418 ? -3.485  -9.685  31.842  1.00 40.42  ? 418 PHE C CE2 1 
ATOM   9965  C CZ  . PHE C 1 418 ? -3.350  -10.675 30.892  1.00 40.66  ? 418 PHE C CZ  1 
ATOM   9966  N N   . SER C 1 419 ? 0.121   -4.570  31.282  1.00 39.85  ? 419 SER C N   1 
ATOM   9967  C CA  . SER C 1 419 ? 0.587   -3.323  31.880  1.00 40.46  ? 419 SER C CA  1 
ATOM   9968  C C   . SER C 1 419 ? -0.593  -2.356  32.018  1.00 45.71  ? 419 SER C C   1 
ATOM   9969  O O   . SER C 1 419 ? -1.433  -2.286  31.144  1.00 48.11  ? 419 SER C O   1 
ATOM   9970  C CB  . SER C 1 419 ? 1.685   -2.722  31.073  1.00 39.89  ? 419 SER C CB  1 
ATOM   9971  O OG  . SER C 1 419 ? 1.740   -1.313  31.224  1.00 39.52  ? 419 SER C OG  1 
ATOM   9972  N N   . ARG C 1 420 ? -0.648  -1.623  33.137  1.00 47.89  ? 420 ARG C N   1 
ATOM   9973  C CA  . ARG C 1 420 ? -1.746  -0.707  33.387  1.00 49.32  ? 420 ARG C CA  1 
ATOM   9974  C C   . ARG C 1 420 ? -1.598  0.530   32.514  1.00 49.10  ? 420 ARG C C   1 
ATOM   9975  O O   . ARG C 1 420 ? -2.579  1.232   32.262  1.00 54.11  ? 420 ARG C O   1 
ATOM   9976  C CB  . ARG C 1 420 ? -1.813  -0.306  34.859  1.00 51.24  ? 420 ARG C CB  1 
ATOM   9977  C CG  . ARG C 1 420 ? -2.264  -1.432  35.768  1.00 51.44  ? 420 ARG C CG  1 
ATOM   9978  C CD  . ARG C 1 420 ? -3.721  -1.714  35.637  1.00 55.17  ? 420 ARG C CD  1 
ATOM   9979  N NE  . ARG C 1 420 ? -4.545  -0.609  36.132  1.00 55.78  ? 420 ARG C NE  1 
ATOM   9980  C CZ  . ARG C 1 420 ? -5.864  -0.655  36.203  1.00 62.51  ? 420 ARG C CZ  1 
ATOM   9981  N NH1 . ARG C 1 420 ? -6.519  -1.714  35.735  1.00 57.46  ? 420 ARG C NH1 1 
ATOM   9982  N NH2 . ARG C 1 420 ? -6.530  0.342   36.758  1.00 66.93  ? 420 ARG C NH2 1 
ATOM   9983  N N   . ASP C 1 421 ? -0.368  0.811   32.086  1.00 46.25  ? 421 ASP C N   1 
ATOM   9984  C CA  . ASP C 1 421 ? -0.120  1.901   31.153  1.00 47.86  ? 421 ASP C CA  1 
ATOM   9985  C C   . ASP C 1 421 ? -0.423  1.413   29.724  1.00 50.67  ? 421 ASP C C   1 
ATOM   9986  O O   . ASP C 1 421 ? 0.391   0.718   29.108  1.00 46.52  ? 421 ASP C O   1 
ATOM   9987  C CB  . ASP C 1 421 ? 1.291   2.442   31.308  1.00 46.36  ? 421 ASP C CB  1 
ATOM   9988  C CG  . ASP C 1 421 ? 1.642   3.629   30.424  1.00 50.25  ? 421 ASP C CG  1 
ATOM   9989  O OD1 . ASP C 1 421 ? 0.834   3.967   29.530  1.00 49.64  ? 421 ASP C OD1 1 
ATOM   9990  O OD2 . ASP C 1 421 ? 2.710   4.209   30.642  1.00 58.21  ? 421 ASP C OD2 1 
ATOM   9991  N N   . LEU C 1 422 ? -1.592  1.813   29.197  1.00 47.79  ? 422 LEU C N   1 
ATOM   9992  C CA  . LEU C 1 422 ? -2.080  1.297   27.931  1.00 41.55  ? 422 LEU C CA  1 
ATOM   9993  C C   . LEU C 1 422 ? -1.188  1.777   26.787  1.00 43.52  ? 422 LEU C C   1 
ATOM   9994  O O   . LEU C 1 422 ? -0.874  1.003   25.866  1.00 42.89  ? 422 LEU C O   1 
ATOM   9995  C CB  . LEU C 1 422 ? -3.536  1.696   27.724  1.00 39.33  ? 422 LEU C CB  1 
ATOM   9996  C CG  . LEU C 1 422 ? -4.555  1.023   28.647  1.00 43.93  ? 422 LEU C CG  1 
ATOM   9997  C CD1 . LEU C 1 422 ? -5.960  1.213   28.106  1.00 44.11  ? 422 LEU C CD1 1 
ATOM   9998  C CD2 . LEU C 1 422 ? -4.265  -0.476  28.854  1.00 46.32  ? 422 LEU C CD2 1 
ATOM   9999  N N   . GLU C 1 423 ? -0.758  3.037   26.848  1.00 44.67  ? 423 GLU C N   1 
ATOM   10000 C CA  . GLU C 1 423 ? 0.083   3.576   25.791  1.00 55.80  ? 423 GLU C CA  1 
ATOM   10001 C C   . GLU C 1 423 ? 1.387   2.764   25.697  1.00 50.71  ? 423 GLU C C   1 
ATOM   10002 O O   . GLU C 1 423 ? 1.784   2.339   24.614  1.00 59.61  ? 423 GLU C O   1 
ATOM   10003 C CB  . GLU C 1 423 ? 0.400   5.048   25.990  1.00 65.71  ? 423 GLU C CB  1 
ATOM   10004 C CG  . GLU C 1 423 ? 1.179   5.636   24.818  1.00 73.86  ? 423 GLU C CG  1 
ATOM   10005 C CD  . GLU C 1 423 ? 1.876   6.949   25.110  1.00 87.29  ? 423 GLU C CD  1 
ATOM   10006 O OE1 . GLU C 1 423 ? 2.402   7.564   24.133  1.00 90.07  ? 423 GLU C OE1 1 
ATOM   10007 O OE2 . GLU C 1 423 ? 1.928   7.349   26.311  1.00 83.53  ? 423 GLU C OE2 1 
ATOM   10008 N N   . ARG C 1 424 ? 2.046   2.558   26.833  1.00 44.19  ? 424 ARG C N   1 
ATOM   10009 C CA  . ARG C 1 424 ? 3.295   1.814   26.854  1.00 43.35  ? 424 ARG C CA  1 
ATOM   10010 C C   . ARG C 1 424 ? 3.062   0.373   26.368  1.00 43.78  ? 424 ARG C C   1 
ATOM   10011 O O   . ARG C 1 424 ? 3.861   -0.162  25.609  1.00 47.40  ? 424 ARG C O   1 
ATOM   10012 C CB  . ARG C 1 424 ? 3.907   1.856   28.252  1.00 44.98  ? 424 ARG C CB  1 
ATOM   10013 C CG  . ARG C 1 424 ? 5.019   0.856   28.504  1.00 47.51  ? 424 ARG C CG  1 
ATOM   10014 C CD  . ARG C 1 424 ? 5.001   0.399   29.946  1.00 52.07  ? 424 ARG C CD  1 
ATOM   10015 N NE  . ARG C 1 424 ? 6.353   0.105   30.416  1.00 59.13  ? 424 ARG C NE  1 
ATOM   10016 C CZ  . ARG C 1 424 ? 6.644   -0.475  31.551  1.00 57.19  ? 424 ARG C CZ  1 
ATOM   10017 N NH1 . ARG C 1 424 ? 5.690   -0.694  32.438  1.00 63.39  ? 424 ARG C NH1 1 
ATOM   10018 N NH2 . ARG C 1 424 ? 7.899   -0.842  31.802  1.00 58.72  ? 424 ARG C NH2 1 
ATOM   10019 N N   . ALA C 1 425 ? 1.971   -0.247  26.805  1.00 40.95  ? 425 ALA C N   1 
ATOM   10020 C CA  . ALA C 1 425 ? 1.689   -1.619  26.416  1.00 45.91  ? 425 ALA C CA  1 
ATOM   10021 C C   . ALA C 1 425 ? 1.612   -1.738  24.873  1.00 46.23  ? 425 ALA C C   1 
ATOM   10022 O O   . ALA C 1 425 ? 2.128   -2.694  24.283  1.00 43.34  ? 425 ALA C O   1 
ATOM   10023 C CB  . ALA C 1 425 ? 0.421   -2.086  27.083  1.00 46.38  ? 425 ALA C CB  1 
ATOM   10024 N N   . VAL C 1 426 ? 0.979   -0.765  24.230  1.00 44.24  ? 426 VAL C N   1 
ATOM   10025 C CA  . VAL C 1 426 ? 0.790   -0.814  22.789  1.00 46.14  ? 426 VAL C CA  1 
ATOM   10026 C C   . VAL C 1 426 ? 2.150   -0.610  22.091  1.00 45.81  ? 426 VAL C C   1 
ATOM   10027 O O   . VAL C 1 426 ? 2.480   -1.317  21.137  1.00 40.71  ? 426 VAL C O   1 
ATOM   10028 C CB  . VAL C 1 426 ? -0.268  0.220   22.322  1.00 42.89  ? 426 VAL C CB  1 
ATOM   10029 C CG1 . VAL C 1 426 ? -0.334  0.327   20.810  1.00 43.67  ? 426 VAL C CG1 1 
ATOM   10030 C CG2 . VAL C 1 426 ? -1.649  -0.105  22.875  1.00 42.11  ? 426 VAL C CG2 1 
ATOM   10031 N N   . ARG C 1 427 ? 2.932   0.350   22.573  1.00 45.14  ? 427 ARG C N   1 
ATOM   10032 C CA  . ARG C 1 427 ? 4.253   0.616   22.002  1.00 48.07  ? 427 ARG C CA  1 
ATOM   10033 C C   . ARG C 1 427 ? 5.111   -0.663  22.062  1.00 43.99  ? 427 ARG C C   1 
ATOM   10034 O O   . ARG C 1 427 ? 5.788   -1.020  21.091  1.00 48.24  ? 427 ARG C O   1 
ATOM   10035 C CB  . ARG C 1 427 ? 4.905   1.766   22.764  1.00 54.68  ? 427 ARG C CB  1 
ATOM   10036 C CG  . ARG C 1 427 ? 5.728   2.705   21.908  1.00 65.63  ? 427 ARG C CG  1 
ATOM   10037 C CD  . ARG C 1 427 ? 6.116   3.964   22.682  1.00 73.05  ? 427 ARG C CD  1 
ATOM   10038 N NE  . ARG C 1 427 ? 6.812   3.635   23.938  1.00 73.57  ? 427 ARG C NE  1 
ATOM   10039 C CZ  . ARG C 1 427 ? 6.419   4.004   25.173  1.00 76.22  ? 427 ARG C CZ  1 
ATOM   10040 N NH1 . ARG C 1 427 ? 5.331   4.741   25.339  1.00 74.19  ? 427 ARG C NH1 1 
ATOM   10041 N NH2 . ARG C 1 427 ? 7.126   3.637   26.231  1.00 76.12  ? 427 ARG C NH2 1 
ATOM   10042 N N   . PHE C 1 428 ? 5.049   -1.357  23.197  1.00 35.33  ? 428 PHE C N   1 
ATOM   10043 C CA  . PHE C 1 428 ? 5.755   -2.608  23.368  1.00 39.99  ? 428 PHE C CA  1 
ATOM   10044 C C   . PHE C 1 428 ? 5.202   -3.628  22.377  1.00 44.39  ? 428 PHE C C   1 
ATOM   10045 O O   . PHE C 1 428 ? 5.971   -4.333  21.712  1.00 45.28  ? 428 PHE C O   1 
ATOM   10046 C CB  . PHE C 1 428 ? 5.636   -3.078  24.817  1.00 36.44  ? 428 PHE C CB  1 
ATOM   10047 C CG  . PHE C 1 428 ? 6.420   -4.337  25.146  1.00 37.37  ? 428 PHE C CG  1 
ATOM   10048 C CD1 . PHE C 1 428 ? 5.874   -5.604  24.918  1.00 38.13  ? 428 PHE C CD1 1 
ATOM   10049 C CD2 . PHE C 1 428 ? 7.681   -4.255  25.742  1.00 40.50  ? 428 PHE C CD2 1 
ATOM   10050 C CE1 . PHE C 1 428 ? 6.580   -6.758  25.247  1.00 40.02  ? 428 PHE C CE1 1 
ATOM   10051 C CE2 . PHE C 1 428 ? 8.386   -5.417  26.077  1.00 40.96  ? 428 PHE C CE2 1 
ATOM   10052 C CZ  . PHE C 1 428 ? 7.841   -6.662  25.819  1.00 41.49  ? 428 PHE C CZ  1 
ATOM   10053 N N   . ALA C 1 429 ? 3.856   -3.699  22.290  1.00 44.29  ? 429 ALA C N   1 
ATOM   10054 C CA  . ALA C 1 429 ? 3.175   -4.690  21.452  1.00 41.52  ? 429 ALA C CA  1 
ATOM   10055 C C   . ALA C 1 429 ? 3.544   -4.511  19.969  1.00 44.11  ? 429 ALA C C   1 
ATOM   10056 O O   . ALA C 1 429 ? 3.723   -5.491  19.255  1.00 44.60  ? 429 ALA C O   1 
ATOM   10057 C CB  . ALA C 1 429 ? 1.686   -4.600  21.660  1.00 42.25  ? 429 ALA C CB  1 
ATOM   10058 N N   . ARG C 1 430 ? 3.678   -3.247  19.519  1.00 52.93  ? 430 ARG C N   1 
ATOM   10059 C CA  . ARG C 1 430 ? 3.974   -2.957  18.110  1.00 50.42  ? 430 ARG C CA  1 
ATOM   10060 C C   . ARG C 1 430 ? 5.347   -3.522  17.730  1.00 50.26  ? 430 ARG C C   1 
ATOM   10061 O O   . ARG C 1 430 ? 5.550   -3.934  16.603  1.00 53.01  ? 430 ARG C O   1 
ATOM   10062 C CB  . ARG C 1 430 ? 3.970   -1.457  17.829  1.00 53.24  ? 430 ARG C CB  1 
ATOM   10063 C CG  . ARG C 1 430 ? 2.683   -0.728  18.193  1.00 56.08  ? 430 ARG C CG  1 
ATOM   10064 C CD  . ARG C 1 430 ? 1.657   -0.827  17.140  1.00 53.89  ? 430 ARG C CD  1 
ATOM   10065 N NE  . ARG C 1 430 ? 2.195   -0.438  15.829  1.00 61.15  ? 430 ARG C NE  1 
ATOM   10066 C CZ  . ARG C 1 430 ? 2.091   0.772   15.282  1.00 56.33  ? 430 ARG C CZ  1 
ATOM   10067 N NH1 . ARG C 1 430 ? 1.730   1.818   16.023  1.00 53.33  ? 430 ARG C NH1 1 
ATOM   10068 N NH2 . ARG C 1 430 ? 2.345   0.928   13.992  1.00 53.79  ? 430 ARG C NH2 1 
ATOM   10069 N N   . GLN C 1 431 ? 6.275   -3.572  18.702  1.00 50.83  ? 431 GLN C N   1 
ATOM   10070 C CA  . GLN C 1 431 ? 7.630   -4.051  18.446  1.00 48.72  ? 431 GLN C CA  1 
ATOM   10071 C C   . GLN C 1 431 ? 7.693   -5.586  18.528  1.00 50.15  ? 431 GLN C C   1 
ATOM   10072 O O   . GLN C 1 431 ? 8.724   -6.177  18.211  1.00 55.20  ? 431 GLN C O   1 
ATOM   10073 C CB  . GLN C 1 431 ? 8.631   -3.434  19.422  1.00 48.72  ? 431 GLN C CB  1 
ATOM   10074 C CG  . GLN C 1 431 ? 8.678   -1.904  19.384  1.00 50.59  ? 431 GLN C CG  1 
ATOM   10075 C CD  . GLN C 1 431 ? 9.458   -1.311  20.544  1.00 59.23  ? 431 GLN C CD  1 
ATOM   10076 O OE1 . GLN C 1 431 ? 10.688  -1.239  20.513  1.00 65.69  ? 431 GLN C OE1 1 
ATOM   10077 N NE2 . GLN C 1 431 ? 8.745   -0.893  21.595  1.00 59.70  ? 431 GLN C NE2 1 
ATOM   10078 N N   . LEU C 1 432 ? 6.608   -6.232  18.960  1.00 43.97  ? 432 LEU C N   1 
ATOM   10079 C CA  . LEU C 1 432 ? 6.600   -7.683  19.013  1.00 45.08  ? 432 LEU C CA  1 
ATOM   10080 C C   . LEU C 1 432 ? 6.599   -8.228  17.591  1.00 48.64  ? 432 LEU C C   1 
ATOM   10081 O O   . LEU C 1 432 ? 5.969   -7.664  16.703  1.00 53.58  ? 432 LEU C O   1 
ATOM   10082 C CB  . LEU C 1 432 ? 5.430   -8.216  19.826  1.00 44.28  ? 432 LEU C CB  1 
ATOM   10083 C CG  . LEU C 1 432 ? 5.610   -8.182  21.349  1.00 49.81  ? 432 LEU C CG  1 
ATOM   10084 C CD1 . LEU C 1 432 ? 4.314   -8.537  22.078  1.00 50.79  ? 432 LEU C CD1 1 
ATOM   10085 C CD2 . LEU C 1 432 ? 6.733   -9.127  21.795  1.00 48.29  ? 432 LEU C CD2 1 
ATOM   10086 N N   . ARG C 1 433 ? 7.357   -9.298  17.392  1.00 55.63  ? 433 ARG C N   1 
ATOM   10087 C CA  . ARG C 1 433 ? 7.447   -9.981  16.112  1.00 65.73  ? 433 ARG C CA  1 
ATOM   10088 C C   . ARG C 1 433 ? 6.365   -11.061 16.071  1.00 63.99  ? 433 ARG C C   1 
ATOM   10089 O O   . ARG C 1 433 ? 6.663   -12.257 16.142  1.00 70.00  ? 433 ARG C O   1 
ATOM   10090 C CB  . ARG C 1 433 ? 8.875   -10.540 15.953  1.00 76.81  ? 433 ARG C CB  1 
ATOM   10091 N N   . ALA C 1 434 ? 5.106   -10.608 16.019  1.00 59.83  ? 434 ALA C N   1 
ATOM   10092 C CA  . ALA C 1 434 ? 3.944   -11.480 16.116  1.00 54.82  ? 434 ALA C CA  1 
ATOM   10093 C C   . ALA C 1 434 ? 2.807   -10.916 15.263  1.00 50.71  ? 434 ALA C C   1 
ATOM   10094 O O   . ALA C 1 434 ? 2.695   -9.706  15.077  1.00 53.13  ? 434 ALA C O   1 
ATOM   10095 C CB  . ALA C 1 434 ? 3.514   -11.626 17.574  1.00 58.11  ? 434 ALA C CB  1 
ATOM   10096 N N   . GLY C 1 435 ? 1.942   -11.805 14.799  1.00 48.98  ? 435 GLY C N   1 
ATOM   10097 C CA  . GLY C 1 435 ? 0.797   -11.423 13.998  1.00 43.18  ? 435 GLY C CA  1 
ATOM   10098 C C   . GLY C 1 435 ? -0.346  -10.899 14.860  1.00 43.01  ? 435 GLY C C   1 
ATOM   10099 O O   . GLY C 1 435 ? -1.107  -10.054 14.414  1.00 40.38  ? 435 GLY C O   1 
ATOM   10100 N N   . MET C 1 436 ? -0.495  -11.451 16.083  1.00 46.88  ? 436 MET C N   1 
ATOM   10101 C CA  . MET C 1 436 ? -1.488  -10.940 17.028  1.00 52.20  ? 436 MET C CA  1 
ATOM   10102 C C   . MET C 1 436 ? -0.848  -10.718 18.407  1.00 46.52  ? 436 MET C C   1 
ATOM   10103 O O   . MET C 1 436 ? -0.071  -11.561 18.881  1.00 42.54  ? 436 MET C O   1 
ATOM   10104 C CB  . MET C 1 436 ? -2.674  -11.898 17.139  1.00 58.63  ? 436 MET C CB  1 
ATOM   10105 C CG  . MET C 1 436 ? -3.839  -11.344 17.985  1.00 79.79  ? 436 MET C CG  1 
ATOM   10106 S SD  . MET C 1 436 ? -5.478  -11.679 17.278  1.00 91.60  ? 436 MET C SD  1 
ATOM   10107 C CE  . MET C 1 436 ? -5.265  -13.442 16.998  1.00 96.06  ? 436 MET C CE  1 
ATOM   10108 N N   . THR C 1 437 ? -1.190  -9.577  19.043  1.00 40.13  ? 437 THR C N   1 
ATOM   10109 C CA  . THR C 1 437 ? -0.883  -9.360  20.464  1.00 43.84  ? 437 THR C CA  1 
ATOM   10110 C C   . THR C 1 437 ? -2.158  -8.981  21.227  1.00 41.76  ? 437 THR C C   1 
ATOM   10111 O O   . THR C 1 437 ? -2.879  -8.086  20.818  1.00 45.16  ? 437 THR C O   1 
ATOM   10112 C CB  . THR C 1 437 ? 0.178   -8.272  20.636  1.00 44.44  ? 437 THR C CB  1 
ATOM   10113 O OG1 . THR C 1 437 ? 1.311   -8.654  19.864  1.00 42.92  ? 437 THR C OG1 1 
ATOM   10114 C CG2 . THR C 1 437 ? 0.584   -8.113  22.093  1.00 43.72  ? 437 THR C CG2 1 
ATOM   10115 N N   . HIS C 1 438 ? -2.360  -9.613  22.393  1.00 40.17  ? 438 HIS C N   1 
ATOM   10116 C CA  . HIS C 1 438 ? -3.458  -9.279  23.290  1.00 42.08  ? 438 HIS C CA  1 
ATOM   10117 C C   . HIS C 1 438 ? -2.932  -8.479  24.494  1.00 37.34  ? 438 HIS C C   1 
ATOM   10118 O O   . HIS C 1 438 ? -2.056  -8.946  25.198  1.00 42.61  ? 438 HIS C O   1 
ATOM   10119 C CB  . HIS C 1 438 ? -4.138  -10.557 23.753  1.00 45.29  ? 438 HIS C CB  1 
ATOM   10120 C CG  . HIS C 1 438 ? -4.957  -11.201 22.700  1.00 59.09  ? 438 HIS C CG  1 
ATOM   10121 N ND1 . HIS C 1 438 ? -6.323  -11.345 22.809  1.00 67.53  ? 438 HIS C ND1 1 
ATOM   10122 C CD2 . HIS C 1 438 ? -4.613  -11.761 21.518  1.00 59.44  ? 438 HIS C CD2 1 
ATOM   10123 C CE1 . HIS C 1 438 ? -6.775  -11.981 21.739  1.00 68.56  ? 438 HIS C CE1 1 
ATOM   10124 N NE2 . HIS C 1 438 ? -5.748  -12.239 20.941  1.00 52.43  ? 438 HIS C NE2 1 
ATOM   10125 N N   . VAL C 1 439 ? -3.502  -7.290  24.724  1.00 33.05  ? 439 VAL C N   1 
ATOM   10126 C CA  . VAL C 1 439 ? -3.101  -6.426  25.832  1.00 37.09  ? 439 VAL C CA  1 
ATOM   10127 C C   . VAL C 1 439 ? -4.080  -6.622  26.998  1.00 38.00  ? 439 VAL C C   1 
ATOM   10128 O O   . VAL C 1 439 ? -5.283  -6.442  26.844  1.00 38.57  ? 439 VAL C O   1 
ATOM   10129 C CB  . VAL C 1 439 ? -3.028  -4.949  25.410  1.00 40.23  ? 439 VAL C CB  1 
ATOM   10130 C CG1 . VAL C 1 439 ? -2.797  -4.038  26.595  1.00 41.13  ? 439 VAL C CG1 1 
ATOM   10131 C CG2 . VAL C 1 439 ? -1.960  -4.710  24.355  1.00 43.63  ? 439 VAL C CG2 1 
ATOM   10132 N N   . ASN C 1 440 ? -3.554  -7.100  28.132  1.00 41.56  ? 440 ASN C N   1 
ATOM   10133 C CA  . ASN C 1 440 ? -4.343  -7.303  29.343  1.00 43.70  ? 440 ASN C CA  1 
ATOM   10134 C C   . ASN C 1 440 ? -5.482  -8.321  29.108  1.00 43.72  ? 440 ASN C C   1 
ATOM   10135 O O   . ASN C 1 440 ? -6.536  -8.191  29.701  1.00 46.21  ? 440 ASN C O   1 
ATOM   10136 C CB  . ASN C 1 440 ? -4.868  -5.960  29.879  1.00 40.20  ? 440 ASN C CB  1 
ATOM   10137 C CG  . ASN C 1 440 ? -3.743  -5.036  30.336  1.00 39.21  ? 440 ASN C CG  1 
ATOM   10138 O OD1 . ASN C 1 440 ? -2.654  -5.488  30.687  1.00 36.64  ? 440 ASN C OD1 1 
ATOM   10139 N ND2 . ASN C 1 440 ? -3.998  -3.750  30.391  1.00 43.17  ? 440 ASN C ND2 1 
ATOM   10140 N N   . ASP C 1 441 ? -5.233  -9.376  28.299  1.00 43.87  ? 441 ASP C N   1 
ATOM   10141 C CA  . ASP C 1 441 ? -6.197  -10.467 28.169  1.00 45.13  ? 441 ASP C CA  1 
ATOM   10142 C C   . ASP C 1 441 ? -5.484  -11.728 27.640  1.00 50.65  ? 441 ASP C C   1 
ATOM   10143 O O   . ASP C 1 441 ? -4.347  -11.666 27.212  1.00 50.80  ? 441 ASP C O   1 
ATOM   10144 C CB  . ASP C 1 441 ? -7.387  -10.032 27.326  1.00 52.37  ? 441 ASP C CB  1 
ATOM   10145 C CG  . ASP C 1 441 ? -8.719  -10.736 27.616  1.00 59.40  ? 441 ASP C CG  1 
ATOM   10146 O OD1 . ASP C 1 441 ? -8.700  -11.846 28.224  1.00 54.92  ? 441 ASP C OD1 1 
ATOM   10147 O OD2 . ASP C 1 441 ? -9.772  -10.174 27.238  1.00 63.27  ? 441 ASP C OD2 1 
ATOM   10148 N N   . ILE C 1 442 ? -6.171  -12.873 27.700  1.00 57.15  ? 442 ILE C N   1 
ATOM   10149 C CA  . ILE C 1 442 ? -5.612  -14.151 27.253  1.00 66.67  ? 442 ILE C CA  1 
ATOM   10150 C C   . ILE C 1 442 ? -5.414  -14.105 25.732  1.00 72.19  ? 442 ILE C C   1 
ATOM   10151 O O   . ILE C 1 442 ? -6.288  -13.647 24.999  1.00 79.25  ? 442 ILE C O   1 
ATOM   10152 C CB  . ILE C 1 442 ? -6.522  -15.334 27.675  1.00 74.56  ? 442 ILE C CB  1 
ATOM   10153 C CG1 . ILE C 1 442 ? -7.799  -15.423 26.807  1.00 86.25  ? 442 ILE C CG1 1 
ATOM   10154 C CG2 . ILE C 1 442 ? -6.864  -15.249 29.149  1.00 73.81  ? 442 ILE C CG2 1 
ATOM   10155 C CD1 . ILE C 1 442 ? -8.839  -16.413 27.312  1.00 86.57  ? 442 ILE C CD1 1 
ATOM   10156 N N   . PRO C 1 443 ? -4.296  -14.639 25.170  1.00 83.53  ? 443 PRO C N   1 
ATOM   10157 C CA  . PRO C 1 443 ? -4.121  -14.659 23.725  1.00 90.17  ? 443 PRO C CA  1 
ATOM   10158 C C   . PRO C 1 443 ? -5.043  -15.685 23.080  1.00 96.32  ? 443 PRO C C   1 
ATOM   10159 O O   . PRO C 1 443 ? -4.539  -16.667 22.506  1.00 108.48 ? 443 PRO C O   1 
ATOM   10160 C CB  . PRO C 1 443 ? -2.639  -15.012 23.511  1.00 78.96  ? 443 PRO C CB  1 
ATOM   10161 C CG  . PRO C 1 443 ? -2.018  -14.936 24.881  1.00 82.68  ? 443 PRO C CG  1 
ATOM   10162 C CD  . PRO C 1 443 ? -3.141  -15.271 25.834  1.00 85.26  ? 443 PRO C CD  1 
ATOM   10163 N N   . VAL C 1 444 ? -6.358  -15.472 23.173  1.00 95.05  ? 444 VAL C N   1 
ATOM   10164 C CA  . VAL C 1 444 ? -7.330  -16.466 22.626  1.00 104.12 ? 444 VAL C CA  1 
ATOM   10165 C C   . VAL C 1 444 ? -8.160  -15.814 21.511  1.00 107.08 ? 444 VAL C C   1 
ATOM   10166 O O   . VAL C 1 444 ? -8.660  -14.688 21.721  1.00 112.36 ? 444 VAL C O   1 
ATOM   10167 C CB  . VAL C 1 444 ? -8.219  -17.070 23.728  1.00 114.93 ? 444 VAL C CB  1 
ATOM   10168 C CG1 . VAL C 1 444 ? -9.650  -17.312 23.264  1.00 125.93 ? 444 VAL C CG1 1 
ATOM   10169 C CG2 . VAL C 1 444 ? -7.607  -18.348 24.288  1.00 111.24 ? 444 VAL C CG2 1 
ATOM   10170 N N   . ASN C 1 445 ? -8.254  -16.481 20.361  1.00 118.15 ? 445 ASN C N   1 
ATOM   10171 C CA  . ASN C 1 445 ? -9.006  -15.953 19.189  1.00 129.78 ? 445 ASN C CA  1 
ATOM   10172 C C   . ASN C 1 445 ? -10.530 -15.979 19.335  1.00 104.66 ? 445 ASN C C   1 
ATOM   10173 O O   . ASN C 1 445 ? -11.036 -16.863 20.057  1.00 83.16  ? 445 ASN C O   1 
ATOM   10174 C CB  . ASN C 1 445 ? -8.659  -16.730 17.925  1.00 137.21 ? 445 ASN C CB  1 
ATOM   10175 C CG  . ASN C 1 445 ? -8.072  -15.825 16.870  1.00 132.19 ? 445 ASN C CG  1 
ATOM   10176 O OD1 . ASN C 1 445 ? -7.215  -16.253 16.090  1.00 113.20 ? 445 ASN C OD1 1 
ATOM   10177 N ND2 . ASN C 1 445 ? -8.510  -14.575 16.841  1.00 123.26 ? 445 ASN C ND2 1 
ATOM   10178 N N   . ASP C 1 446 ? -11.224 -15.035 18.691  1.00 91.96  ? 446 ASP C N   1 
ATOM   10179 C CA  . ASP C 1 446 ? -12.715 -15.051 18.591  1.00 119.35 ? 446 ASP C CA  1 
ATOM   10180 C C   . ASP C 1 446 ? -13.489 -15.037 19.912  1.00 121.49 ? 446 ASP C C   1 
ATOM   10181 O O   . ASP C 1 446 ? -13.176 -14.190 20.774  1.00 93.54  ? 446 ASP C O   1 
ATOM   10182 C CB  . ASP C 1 446 ? -13.188 -16.242 17.766  1.00 118.60 ? 446 ASP C CB  1 
ATOM   10183 C CG  . ASP C 1 446 ? -12.293 -16.633 16.599  1.00 102.31 ? 446 ASP C CG  1 
ATOM   10184 O OD1 . ASP C 1 446 ? -12.210 -17.844 16.303  1.00 97.26  ? 446 ASP C OD1 1 
ATOM   10185 O OD2 . ASP C 1 446 ? -11.681 -15.725 15.997  1.00 81.10  ? 446 ASP C OD2 1 
ATOM   10186 N N   . SER C 1 458 ? -17.871 -12.323 16.338  1.00 124.99 ? 458 SER C N   1 
ATOM   10187 C CA  . SER C 1 458 ? -18.320 -12.897 15.044  1.00 122.08 ? 458 SER C CA  1 
ATOM   10188 C C   . SER C 1 458 ? -17.224 -12.721 13.984  1.00 111.15 ? 458 SER C C   1 
ATOM   10189 O O   . SER C 1 458 ? -16.259 -13.512 13.994  1.00 125.32 ? 458 SER C O   1 
ATOM   10190 C CB  . SER C 1 458 ? -19.622 -12.281 14.606  1.00 128.88 ? 458 SER C CB  1 
ATOM   10191 O OG  . SER C 1 458 ? -20.694 -13.201 14.757  1.00 112.63 ? 458 SER C OG  1 
ATOM   10192 N N   . GLY C 1 459 ? -17.327 -11.683 13.159  1.00 103.87 ? 459 GLY C N   1 
ATOM   10193 C CA  . GLY C 1 459 ? -16.330 -11.394 12.107  1.00 95.19  ? 459 GLY C CA  1 
ATOM   10194 C C   . GLY C 1 459 ? -15.318 -10.451 12.702  1.00 85.63  ? 459 GLY C C   1 
ATOM   10195 O O   . GLY C 1 459 ? -14.462 -9.944  11.951  1.00 66.88  ? 459 GLY C O   1 
ATOM   10196 N N   . LEU C 1 460 ? -15.423 -10.212 14.009  1.00 83.29  ? 460 LEU C N   1 
ATOM   10197 C CA  . LEU C 1 460 ? -14.586 -9.195  14.690  1.00 90.24  ? 460 LEU C CA  1 
ATOM   10198 C C   . LEU C 1 460 ? -13.080 -9.493  14.609  1.00 89.08  ? 460 LEU C C   1 
ATOM   10199 O O   . LEU C 1 460 ? -12.328 -8.516  14.460  1.00 92.70  ? 460 LEU C O   1 
ATOM   10200 C CB  . LEU C 1 460 ? -15.105 -9.168  16.126  1.00 86.09  ? 460 LEU C CB  1 
ATOM   10201 C CG  . LEU C 1 460 ? -16.632 -9.131  16.258  1.00 81.93  ? 460 LEU C CG  1 
ATOM   10202 C CD1 . LEU C 1 460 ? -17.097 -9.213  17.696  1.00 74.17  ? 460 LEU C CD1 1 
ATOM   10203 C CD2 . LEU C 1 460 ? -17.241 -7.923  15.563  1.00 78.03  ? 460 LEU C CD2 1 
ATOM   10204 N N   . GLY C 1 461 ? -12.629 -10.742 14.735  1.00 84.08  ? 461 GLY C N   1 
ATOM   10205 C CA  . GLY C 1 461 ? -11.165 -10.929 14.688  1.00 97.19  ? 461 GLY C CA  1 
ATOM   10206 C C   . GLY C 1 461 ? -10.701 -12.100 13.852  1.00 97.06  ? 461 GLY C C   1 
ATOM   10207 O O   . GLY C 1 461 ? -11.495 -13.050 13.698  1.00 133.12 ? 461 GLY C O   1 
ATOM   10208 N N   . ARG C 1 462 ? -9.477  -12.035 13.310  1.00 71.50  ? 462 ARG C N   1 
ATOM   10209 C CA  . ARG C 1 462 ? -8.912  -13.225 12.621  1.00 74.85  ? 462 ARG C CA  1 
ATOM   10210 C C   . ARG C 1 462 ? -9.881  -13.613 11.503  1.00 81.23  ? 462 ARG C C   1 
ATOM   10211 O O   . ARG C 1 462 ? -10.073 -12.801 10.583  1.00 114.47 ? 462 ARG C O   1 
ATOM   10212 C CB  . ARG C 1 462 ? -8.617  -14.397 13.564  1.00 74.69  ? 462 ARG C CB  1 
ATOM   10213 N N   . PHE C 1 463 ? -10.423 -14.829 11.556  1.00 67.98  ? 463 PHE C N   1 
ATOM   10214 C CA  . PHE C 1 463 ? -11.259 -15.295 10.428  1.00 74.66  ? 463 PHE C CA  1 
ATOM   10215 C C   . PHE C 1 463 ? -12.371 -14.300 10.232  1.00 77.15  ? 463 PHE C C   1 
ATOM   10216 O O   . PHE C 1 463 ? -13.018 -13.872 11.212  1.00 111.53 ? 463 PHE C O   1 
ATOM   10217 C CB  . PHE C 1 463 ? -11.764 -16.648 10.937  1.00 62.60  ? 463 PHE C CB  1 
ATOM   10218 C CG  . PHE C 1 463 ? -13.010 -17.289 10.334  1.00 65.68  ? 463 PHE C CG  1 
ATOM   10219 C CD1 . PHE C 1 463 ? -12.918 -18.488 9.638   1.00 61.69  ? 463 PHE C CD1 1 
ATOM   10220 C CD2 . PHE C 1 463 ? -14.277 -16.745 10.523  1.00 62.61  ? 463 PHE C CD2 1 
ATOM   10221 C CE1 . PHE C 1 463 ? -14.044 -19.089 9.102   1.00 51.06  ? 463 PHE C CE1 1 
ATOM   10222 C CE2 . PHE C 1 463 ? -15.400 -17.350 9.985   1.00 56.96  ? 463 PHE C CE2 1 
ATOM   10223 C CZ  . PHE C 1 463 ? -15.282 -18.521 9.278   1.00 54.53  ? 463 PHE C CZ  1 
ATOM   10224 N N   . ASN C 1 464 ? -12.600 -13.946 8.970   1.00 55.21  ? 464 ASN C N   1 
ATOM   10225 C CA  . ASN C 1 464 ? -13.630 -12.941 8.616   1.00 48.48  ? 464 ASN C CA  1 
ATOM   10226 C C   . ASN C 1 464 ? -13.869 -13.115 7.121   1.00 43.17  ? 464 ASN C C   1 
ATOM   10227 O O   . ASN C 1 464 ? -13.146 -13.922 6.505   1.00 47.94  ? 464 ASN C O   1 
ATOM   10228 C CB  . ASN C 1 464 ? -13.198 -11.519 8.957   1.00 43.34  ? 464 ASN C CB  1 
ATOM   10229 C CG  . ASN C 1 464 ? -11.850 -11.147 8.386   1.00 44.32  ? 464 ASN C CG  1 
ATOM   10230 O OD1 . ASN C 1 464 ? -11.661 -11.142 7.166   1.00 54.39  ? 464 ASN C OD1 1 
ATOM   10231 N ND2 . ASN C 1 464 ? -10.906 -10.803 9.249   1.00 44.46  ? 464 ASN C ND2 1 
ATOM   10232 N N   . GLY C 1 465 ? -14.815 -12.381 6.547   1.00 47.45  ? 465 GLY C N   1 
ATOM   10233 C CA  . GLY C 1 465 ? -15.083 -12.631 5.132   1.00 46.68  ? 465 GLY C CA  1 
ATOM   10234 C C   . GLY C 1 465 ? -13.890 -12.285 4.236   1.00 46.87  ? 465 GLY C C   1 
ATOM   10235 O O   . GLY C 1 465 ? -13.633 -12.980 3.263   1.00 48.91  ? 465 GLY C O   1 
ATOM   10236 N N   . ASP C 1 466 ? -13.195 -11.186 4.549   1.00 45.55  ? 466 ASP C N   1 
ATOM   10237 C CA  . ASP C 1 466 ? -12.087 -10.721 3.724   1.00 46.08  ? 466 ASP C CA  1 
ATOM   10238 C C   . ASP C 1 466 ? -11.027 -11.798 3.648   1.00 44.08  ? 466 ASP C C   1 
ATOM   10239 O O   . ASP C 1 466 ? -10.569 -12.136 2.566   1.00 47.50  ? 466 ASP C O   1 
ATOM   10240 C CB  . ASP C 1 466 ? -11.521 -9.409  4.232   1.00 51.63  ? 466 ASP C CB  1 
ATOM   10241 C CG  . ASP C 1 466 ? -12.516 -8.261  4.232   1.00 58.08  ? 466 ASP C CG  1 
ATOM   10242 O OD1 . ASP C 1 466 ? -13.240 -8.134  3.232   1.00 51.19  ? 466 ASP C OD1 1 
ATOM   10243 O OD2 . ASP C 1 466 ? -12.582 -7.524  5.253   1.00 71.04  ? 466 ASP C OD2 1 
ATOM   10244 N N   . TRP C 1 467 ? -10.671 -12.359 4.807   1.00 47.04  ? 467 TRP C N   1 
ATOM   10245 C CA  . TRP C 1 467 ? -9.661  -13.401 4.867   1.00 41.36  ? 467 TRP C CA  1 
ATOM   10246 C C   . TRP C 1 467 ? -10.141 -14.624 4.093   1.00 37.13  ? 467 TRP C C   1 
ATOM   10247 O O   . TRP C 1 467 ? -9.404  -15.182 3.289   1.00 38.67  ? 467 TRP C O   1 
ATOM   10248 C CB  . TRP C 1 467 ? -9.325  -13.764 6.323   1.00 41.03  ? 467 TRP C CB  1 
ATOM   10249 C CG  . TRP C 1 467 ? -8.664  -15.105 6.464   1.00 46.04  ? 467 TRP C CG  1 
ATOM   10250 C CD1 . TRP C 1 467 ? -7.337  -15.384 6.320   1.00 48.28  ? 467 TRP C CD1 1 
ATOM   10251 C CD2 . TRP C 1 467 ? -9.321  -16.366 6.670   1.00 43.57  ? 467 TRP C CD2 1 
ATOM   10252 N NE1 . TRP C 1 467 ? -7.118  -16.729 6.452   1.00 49.66  ? 467 TRP C NE1 1 
ATOM   10253 C CE2 . TRP C 1 467 ? -8.315  -17.358 6.666   1.00 47.85  ? 467 TRP C CE2 1 
ATOM   10254 C CE3 . TRP C 1 467 ? -10.647 -16.749 6.875   1.00 44.77  ? 467 TRP C CE3 1 
ATOM   10255 C CZ2 . TRP C 1 467 ? -8.598  -18.709 6.863   1.00 47.29  ? 467 TRP C CZ2 1 
ATOM   10256 C CZ3 . TRP C 1 467 ? -10.929 -18.083 7.081   1.00 46.62  ? 467 TRP C CZ3 1 
ATOM   10257 C CH2 . TRP C 1 467 ? -9.913  -19.050 7.075   1.00 48.25  ? 467 TRP C CH2 1 
ATOM   10258 N N   . ALA C 1 468 ? -11.382 -15.028 4.344   1.00 34.53  ? 468 ALA C N   1 
ATOM   10259 C CA  . ALA C 1 468 ? -11.899 -16.256 3.784   1.00 35.98  ? 468 ALA C CA  1 
ATOM   10260 C C   . ALA C 1 468 ? -11.930 -16.168 2.256   1.00 35.58  ? 468 ALA C C   1 
ATOM   10261 O O   . ALA C 1 468 ? -11.554 -17.114 1.561   1.00 39.07  ? 468 ALA C O   1 
ATOM   10262 C CB  . ALA C 1 468 ? -13.254 -16.541 4.367   1.00 37.66  ? 468 ALA C CB  1 
ATOM   10263 N N   . ILE C 1 469 ? -12.347 -15.018 1.740   1.00 35.60  ? 469 ILE C N   1 
ATOM   10264 C CA  . ILE C 1 469 ? -12.533 -14.861 0.309   1.00 39.07  ? 469 ILE C CA  1 
ATOM   10265 C C   . ILE C 1 469 ? -11.169 -14.878 -0.370  1.00 37.75  ? 469 ILE C C   1 
ATOM   10266 O O   . ILE C 1 469 ? -10.999 -15.492 -1.419  1.00 38.33  ? 469 ILE C O   1 
ATOM   10267 C CB  . ILE C 1 469 ? -13.338 -13.577 0.005   1.00 47.26  ? 469 ILE C CB  1 
ATOM   10268 C CG1 . ILE C 1 469 ? -14.813 -13.766 0.353   1.00 53.37  ? 469 ILE C CG1 1 
ATOM   10269 C CG2 . ILE C 1 469 ? -13.153 -13.118 -1.451  1.00 49.80  ? 469 ILE C CG2 1 
ATOM   10270 C CD1 . ILE C 1 469 ? -15.640 -12.516 0.215   1.00 59.75  ? 469 ILE C CD1 1 
ATOM   10271 N N   . GLU C 1 470 ? -10.197 -14.222 0.248   1.00 37.84  ? 470 GLU C N   1 
ATOM   10272 C CA  . GLU C 1 470 ? -8.846  -14.214 -0.279  1.00 42.90  ? 470 GLU C CA  1 
ATOM   10273 C C   . GLU C 1 470 ? -8.288  -15.648 -0.317  1.00 41.33  ? 470 GLU C C   1 
ATOM   10274 O O   . GLU C 1 470 ? -7.643  -16.031 -1.267  1.00 48.22  ? 470 GLU C O   1 
ATOM   10275 C CB  . GLU C 1 470 ? -7.961  -13.287 0.548   1.00 48.75  ? 470 GLU C CB  1 
ATOM   10276 C CG  . GLU C 1 470 ? -6.553  -13.145 -0.021  1.00 62.50  ? 470 GLU C CG  1 
ATOM   10277 C CD  . GLU C 1 470 ? -6.441  -12.237 -1.255  1.00 74.43  ? 470 GLU C CD  1 
ATOM   10278 O OE1 . GLU C 1 470 ? -7.404  -11.467 -1.564  1.00 72.71  ? 470 GLU C OE1 1 
ATOM   10279 O OE2 . GLU C 1 470 ? -5.384  -12.310 -1.919  1.00 88.92  ? 470 GLU C OE2 1 
ATOM   10280 N N   . GLU C 1 471 ? -8.532  -16.421 0.741   1.00 46.07  ? 471 GLU C N   1 
ATOM   10281 C CA  . GLU C 1 471 ? -7.934  -17.742 0.867   1.00 45.12  ? 471 GLU C CA  1 
ATOM   10282 C C   . GLU C 1 471 ? -8.617  -18.756 -0.064  1.00 41.85  ? 471 GLU C C   1 
ATOM   10283 O O   . GLU C 1 471 ? -7.952  -19.603 -0.619  1.00 41.42  ? 471 GLU C O   1 
ATOM   10284 C CB  . GLU C 1 471 ? -7.971  -18.238 2.303   1.00 48.07  ? 471 GLU C CB  1 
ATOM   10285 C CG  . GLU C 1 471 ? -7.194  -19.536 2.494   1.00 53.40  ? 471 GLU C CG  1 
ATOM   10286 C CD  . GLU C 1 471 ? -6.288  -19.516 3.714   1.00 66.12  ? 471 GLU C CD  1 
ATOM   10287 O OE1 . GLU C 1 471 ? -5.506  -18.538 3.821   1.00 64.31  ? 471 GLU C OE1 1 
ATOM   10288 O OE2 . GLU C 1 471 ? -6.355  -20.457 4.560   1.00 68.46  ? 471 GLU C OE2 1 
ATOM   10289 N N   . PHE C 1 472 ? -9.957  -18.698 -0.190  1.00 40.04  ? 472 PHE C N   1 
ATOM   10290 C CA  . PHE C 1 472 ? -10.694 -19.796 -0.822  1.00 39.15  ? 472 PHE C CA  1 
ATOM   10291 C C   . PHE C 1 472 ? -11.273 -19.393 -2.195  1.00 33.84  ? 472 PHE C C   1 
ATOM   10292 O O   . PHE C 1 472 ? -12.033 -20.151 -2.776  1.00 29.70  ? 472 PHE C O   1 
ATOM   10293 C CB  . PHE C 1 472 ? -11.785 -20.286 0.134   1.00 41.39  ? 472 PHE C CB  1 
ATOM   10294 C CG  . PHE C 1 472 ? -11.229 -20.810 1.446   1.00 38.50  ? 472 PHE C CG  1 
ATOM   10295 C CD1 . PHE C 1 472 ? -10.485 -22.001 1.480   1.00 37.17  ? 472 PHE C CD1 1 
ATOM   10296 C CD2 . PHE C 1 472 ? -11.386 -20.088 2.628   1.00 38.02  ? 472 PHE C CD2 1 
ATOM   10297 C CE1 . PHE C 1 472 ? -9.920  -22.455 2.668   1.00 34.50  ? 472 PHE C CE1 1 
ATOM   10298 C CE2 . PHE C 1 472 ? -10.862 -20.571 3.827   1.00 39.04  ? 472 PHE C CE2 1 
ATOM   10299 C CZ  . PHE C 1 472 ? -10.117 -21.754 3.840   1.00 36.69  ? 472 PHE C CZ  1 
ATOM   10300 N N   . THR C 1 473 ? -10.880 -18.229 -2.728  1.00 35.85  ? 473 THR C N   1 
ATOM   10301 C CA  . THR C 1 473 ? -11.185 -17.897 -4.123  1.00 36.77  ? 473 THR C CA  1 
ATOM   10302 C C   . THR C 1 473 ? -9.931  -17.361 -4.820  1.00 36.72  ? 473 THR C C   1 
ATOM   10303 O O   . THR C 1 473 ? -8.958  -16.971 -4.176  1.00 41.71  ? 473 THR C O   1 
ATOM   10304 C CB  . THR C 1 473 ? -12.353 -16.899 -4.221  1.00 36.34  ? 473 THR C CB  1 
ATOM   10305 O OG1 . THR C 1 473 ? -11.913 -15.626 -3.739  1.00 37.86  ? 473 THR C OG1 1 
ATOM   10306 C CG2 . THR C 1 473 ? -13.571 -17.366 -3.455  1.00 37.42  ? 473 THR C CG2 1 
ATOM   10307 N N   . THR C 1 474 ? -9.995  -17.343 -6.149  1.00 39.57  ? 474 THR C N   1 
ATOM   10308 C CA  . THR C 1 474 ? -8.933  -16.836 -6.996  1.00 43.59  ? 474 THR C CA  1 
ATOM   10309 C C   . THR C 1 474 ? -9.533  -15.945 -8.099  1.00 44.35  ? 474 THR C C   1 
ATOM   10310 O O   . THR C 1 474 ? -10.722 -16.039 -8.409  1.00 42.61  ? 474 THR C O   1 
ATOM   10311 C CB  . THR C 1 474 ? -8.180  -18.013 -7.593  1.00 45.05  ? 474 THR C CB  1 
ATOM   10312 O OG1 . THR C 1 474 ? -7.202  -17.379 -8.395  1.00 62.55  ? 474 THR C OG1 1 
ATOM   10313 C CG2 . THR C 1 474 ? -9.067  -18.910 -8.446  1.00 44.11  ? 474 THR C CG2 1 
ATOM   10314 N N   . ASP C 1 475 ? -8.678  -15.126 -8.714  1.00 44.86  ? 475 ASP C N   1 
ATOM   10315 C CA  . ASP C 1 475 ? -9.099  -14.157 -9.714  1.00 48.28  ? 475 ASP C CA  1 
ATOM   10316 C C   . ASP C 1 475 ? -8.691  -14.626 -11.097 1.00 47.00  ? 475 ASP C C   1 
ATOM   10317 O O   . ASP C 1 475 ? -7.585  -15.124 -11.287 1.00 52.09  ? 475 ASP C O   1 
ATOM   10318 C CB  . ASP C 1 475 ? -8.501  -12.792 -9.460  1.00 54.21  ? 475 ASP C CB  1 
ATOM   10319 C CG  . ASP C 1 475 ? -9.151  -12.034 -8.335  1.00 68.56  ? 475 ASP C CG  1 
ATOM   10320 O OD1 . ASP C 1 475 ? -8.866  -10.831 -8.199  1.00 80.49  ? 475 ASP C OD1 1 
ATOM   10321 O OD2 . ASP C 1 475 ? -9.933  -12.659 -7.607  1.00 74.16  ? 475 ASP C OD2 1 
ATOM   10322 N N   . HIS C 1 476 ? -9.586  -14.385 -12.065 1.00 42.22  ? 476 HIS C N   1 
ATOM   10323 C CA  . HIS C 1 476 ? -9.309  -14.597 -13.467 1.00 40.30  ? 476 HIS C CA  1 
ATOM   10324 C C   . HIS C 1 476 ? -9.541  -13.272 -14.220 1.00 35.81  ? 476 HIS C C   1 
ATOM   10325 O O   . HIS C 1 476 ? -10.678 -12.849 -14.396 1.00 35.12  ? 476 HIS C O   1 
ATOM   10326 C CB  . HIS C 1 476 ? -10.170 -15.759 -13.993 1.00 38.32  ? 476 HIS C CB  1 
ATOM   10327 C CG  . HIS C 1 476 ? -9.808  -16.198 -15.353 1.00 44.45  ? 476 HIS C CG  1 
ATOM   10328 N ND1 . HIS C 1 476 ? -10.356 -17.314 -15.939 1.00 49.96  ? 476 HIS C ND1 1 
ATOM   10329 C CD2 . HIS C 1 476 ? -8.971  -15.659 -16.280 1.00 49.65  ? 476 HIS C CD2 1 
ATOM   10330 C CE1 . HIS C 1 476 ? -9.854  -17.456 -17.166 1.00 52.59  ? 476 HIS C CE1 1 
ATOM   10331 N NE2 . HIS C 1 476 ? -9.004  -16.467 -17.390 1.00 49.37  ? 476 HIS C NE2 1 
ATOM   10332 N N   . TRP C 1 477 ? -8.443  -12.634 -14.663 1.00 37.66  ? 477 TRP C N   1 
ATOM   10333 C CA  . TRP C 1 477 ? -8.502  -11.409 -15.470 1.00 39.63  ? 477 TRP C CA  1 
ATOM   10334 C C   . TRP C 1 477 ? -8.840  -11.745 -16.917 1.00 43.67  ? 477 TRP C C   1 
ATOM   10335 O O   . TRP C 1 477 ? -8.098  -12.465 -17.558 1.00 42.40  ? 477 TRP C O   1 
ATOM   10336 C CB  . TRP C 1 477 ? -7.161  -10.675 -15.410 1.00 40.35  ? 477 TRP C CB  1 
ATOM   10337 C CG  . TRP C 1 477 ? -6.916  -9.950  -14.118 1.00 47.67  ? 477 TRP C CG  1 
ATOM   10338 C CD1 . TRP C 1 477 ? -6.698  -10.499 -12.885 1.00 50.71  ? 477 TRP C CD1 1 
ATOM   10339 C CD2 . TRP C 1 477 ? -6.850  -8.529  -13.940 1.00 42.92  ? 477 TRP C CD2 1 
ATOM   10340 N NE1 . TRP C 1 477 ? -6.529  -9.512  -11.951 1.00 49.73  ? 477 TRP C NE1 1 
ATOM   10341 C CE2 . TRP C 1 477 ? -6.614  -8.296  -12.566 1.00 44.86  ? 477 TRP C CE2 1 
ATOM   10342 C CE3 . TRP C 1 477 ? -6.969  -7.440  -14.800 1.00 45.34  ? 477 TRP C CE3 1 
ATOM   10343 C CZ2 . TRP C 1 477 ? -6.503  -7.018  -12.040 1.00 47.67  ? 477 TRP C CZ2 1 
ATOM   10344 C CZ3 . TRP C 1 477 ? -6.860  -6.166  -14.281 1.00 46.52  ? 477 TRP C CZ3 1 
ATOM   10345 C CH2 . TRP C 1 477 ? -6.637  -5.960  -12.918 1.00 50.74  ? 477 TRP C CH2 1 
ATOM   10346 N N   . ILE C 1 478 ? -9.931  -11.162 -17.444 1.00 43.62  ? 478 ILE C N   1 
ATOM   10347 C CA  . ILE C 1 478 ? -10.235 -11.267 -18.864 1.00 45.20  ? 478 ILE C CA  1 
ATOM   10348 C C   . ILE C 1 478 ? -10.338 -9.862  -19.461 1.00 45.77  ? 478 ILE C C   1 
ATOM   10349 O O   . ILE C 1 478 ? -11.280 -9.116  -19.172 1.00 42.62  ? 478 ILE C O   1 
ATOM   10350 C CB  . ILE C 1 478 ? -11.514 -12.073 -19.100 1.00 47.71  ? 478 ILE C CB  1 
ATOM   10351 C CG1 . ILE C 1 478 ? -11.391 -13.477 -18.580 1.00 48.58  ? 478 ILE C CG1 1 
ATOM   10352 C CG2 . ILE C 1 478 ? -11.894 -12.059 -20.577 1.00 56.16  ? 478 ILE C CG2 1 
ATOM   10353 C CD1 . ILE C 1 478 ? -12.721 -14.121 -18.266 1.00 46.40  ? 478 ILE C CD1 1 
ATOM   10354 N N   . SER C 1 479 ? -9.387  -9.531  -20.326 1.00 42.64  ? 479 SER C N   1 
ATOM   10355 C CA  . SER C 1 479 ? -9.418  -8.277  -21.051 1.00 46.81  ? 479 SER C CA  1 
ATOM   10356 C C   . SER C 1 479 ? -10.119 -8.479  -22.414 1.00 48.13  ? 479 SER C C   1 
ATOM   10357 O O   . SER C 1 479 ? -9.797  -9.403  -23.165 1.00 45.60  ? 479 SER C O   1 
ATOM   10358 C CB  . SER C 1 479 ? -8.020  -7.717  -21.210 1.00 48.22  ? 479 SER C CB  1 
ATOM   10359 O OG  . SER C 1 479 ? -7.448  -8.141  -22.433 1.00 57.16  ? 479 SER C OG  1 
ATOM   10360 N N   . VAL C 1 480 ? -11.099 -7.624  -22.699 1.00 49.68  ? 480 VAL C N   1 
ATOM   10361 C CA  . VAL C 1 480 ? -11.893 -7.735  -23.911 1.00 59.43  ? 480 VAL C CA  1 
ATOM   10362 C C   . VAL C 1 480 ? -11.625 -6.519  -24.804 1.00 54.98  ? 480 VAL C C   1 
ATOM   10363 O O   . VAL C 1 480 ? -11.735 -5.380  -24.351 1.00 49.88  ? 480 VAL C O   1 
ATOM   10364 C CB  . VAL C 1 480 ? -13.392 -7.849  -23.587 1.00 61.12  ? 480 VAL C CB  1 
ATOM   10365 C CG1 . VAL C 1 480 ? -14.178 -8.325  -24.792 1.00 62.48  ? 480 VAL C CG1 1 
ATOM   10366 C CG2 . VAL C 1 480 ? -13.655 -8.747  -22.373 1.00 62.48  ? 480 VAL C CG2 1 
ATOM   10367 N N   . GLN C 1 481 ? -11.300 -6.789  -26.080 1.00 56.84  ? 481 GLN C N   1 
ATOM   10368 C CA  . GLN C 1 481 ? -11.212 -5.750  -27.105 1.00 62.86  ? 481 GLN C CA  1 
ATOM   10369 C C   . GLN C 1 481 ? -12.512 -5.729  -27.912 1.00 56.90  ? 481 GLN C C   1 
ATOM   10370 O O   . GLN C 1 481 ? -12.835 -6.703  -28.576 1.00 57.97  ? 481 GLN C O   1 
ATOM   10371 C CB  . GLN C 1 481 ? -10.011 -6.016  -28.022 1.00 67.19  ? 481 GLN C CB  1 
ATOM   10372 C CG  . GLN C 1 481 ? -9.803  -4.968  -29.126 1.00 69.92  ? 481 GLN C CG  1 
ATOM   10373 C CD  . GLN C 1 481 ? -9.417  -3.597  -28.594 1.00 70.26  ? 481 GLN C CD  1 
ATOM   10374 O OE1 . GLN C 1 481 ? -10.183 -2.621  -28.676 1.00 63.65  ? 481 GLN C OE1 1 
ATOM   10375 N NE2 . GLN C 1 481 ? -8.228  -3.514  -28.026 1.00 70.12  ? 481 GLN C NE2 1 
ATOM   10376 N N   . HIS C 1 482 ? -13.241 -4.606  -27.842 1.00 58.34  ? 482 HIS C N   1 
ATOM   10377 C CA  . HIS C 1 482 ? -14.508 -4.445  -28.557 1.00 66.14  ? 482 HIS C CA  1 
ATOM   10378 C C   . HIS C 1 482 ? -14.253 -3.865  -29.963 1.00 59.20  ? 482 HIS C C   1 
ATOM   10379 O O   . HIS C 1 482 ? -13.302 -3.050  -30.077 1.00 65.21  ? 482 HIS C O   1 
ATOM   10380 C CB  . HIS C 1 482 ? -15.473 -3.556  -27.753 1.00 67.23  ? 482 HIS C CB  1 
ATOM   10381 C CG  . HIS C 1 482 ? -15.704 -4.014  -26.346 1.00 67.43  ? 482 HIS C CG  1 
ATOM   10382 N ND1 . HIS C 1 482 ? -16.794 -4.766  -25.958 1.00 65.99  ? 482 HIS C ND1 1 
ATOM   10383 C CD2 . HIS C 1 482 ? -14.979 -3.810  -25.234 1.00 69.88  ? 482 HIS C CD2 1 
ATOM   10384 C CE1 . HIS C 1 482 ? -16.720 -5.005  -24.654 1.00 68.43  ? 482 HIS C CE1 1 
ATOM   10385 N NE2 . HIS C 1 482 ? -15.626 -4.431  -24.193 1.00 70.60  ? 482 HIS C NE2 1 
ATOM   10386 N N   . ASP D 1 3   ? -48.885 -19.463 16.971  1.00 139.05 ? 3   ASP D N   1 
ATOM   10387 C CA  . ASP D 1 3   ? -49.806 -19.347 18.136  1.00 124.03 ? 3   ASP D CA  1 
ATOM   10388 C C   . ASP D 1 3   ? -50.890 -18.313 17.823  1.00 104.61 ? 3   ASP D C   1 
ATOM   10389 O O   . ASP D 1 3   ? -51.321 -18.234 16.654  1.00 105.22 ? 3   ASP D O   1 
ATOM   10390 C CB  . ASP D 1 3   ? -49.055 -18.994 19.410  1.00 133.39 ? 3   ASP D CB  1 
ATOM   10391 C CG  . ASP D 1 3   ? -48.134 -17.786 19.310  1.00 142.66 ? 3   ASP D CG  1 
ATOM   10392 O OD1 . ASP D 1 3   ? -47.113 -17.883 18.598  1.00 154.08 ? 3   ASP D OD1 1 
ATOM   10393 O OD2 . ASP D 1 3   ? -48.448 -16.757 19.944  1.00 145.05 ? 3   ASP D OD2 1 
ATOM   10394 N N   . SER D 1 4   ? -51.318 -17.561 18.836  1.00 80.61  ? 4   SER D N   1 
ATOM   10395 C CA  . SER D 1 4   ? -52.367 -16.531 18.638  1.00 71.18  ? 4   SER D CA  1 
ATOM   10396 C C   . SER D 1 4   ? -51.869 -15.395 17.735  1.00 56.37  ? 4   SER D C   1 
ATOM   10397 O O   . SER D 1 4   ? -50.688 -15.009 17.865  1.00 50.90  ? 4   SER D O   1 
ATOM   10398 C CB  . SER D 1 4   ? -52.835 -15.996 19.963  1.00 73.48  ? 4   SER D CB  1 
ATOM   10399 O OG  . SER D 1 4   ? -51.729 -15.714 20.808  1.00 73.38  ? 4   SER D OG  1 
ATOM   10400 N N   . ARG D 1 5   ? -52.734 -14.886 16.856  1.00 44.26  ? 5   ARG D N   1 
ATOM   10401 C CA  . ARG D 1 5   ? -52.384 -13.709 16.020  1.00 48.05  ? 5   ARG D CA  1 
ATOM   10402 C C   . ARG D 1 5   ? -52.327 -12.462 16.919  1.00 46.30  ? 5   ARG D C   1 
ATOM   10403 O O   . ARG D 1 5   ? -53.066 -12.424 17.922  1.00 49.08  ? 5   ARG D O   1 
ATOM   10404 C CB  . ARG D 1 5   ? -53.400 -13.546 14.886  1.00 43.25  ? 5   ARG D CB  1 
ATOM   10405 C CG  . ARG D 1 5   ? -53.182 -14.452 13.684  1.00 43.11  ? 5   ARG D CG  1 
ATOM   10406 C CD  . ARG D 1 5   ? -53.950 -13.941 12.477  1.00 43.40  ? 5   ARG D CD  1 
ATOM   10407 N NE  . ARG D 1 5   ? -53.742 -14.764 11.281  1.00 47.53  ? 5   ARG D NE  1 
ATOM   10408 C CZ  . ARG D 1 5   ? -54.013 -14.373 10.043  1.00 47.32  ? 5   ARG D CZ  1 
ATOM   10409 N NH1 . ARG D 1 5   ? -54.484 -13.159 9.822   1.00 51.64  ? 5   ARG D NH1 1 
ATOM   10410 N NH2 . ARG D 1 5   ? -53.807 -15.194 9.030   1.00 45.47  ? 5   ARG D NH2 1 
ATOM   10411 N N   . TYR D 1 6   ? -51.480 -11.490 16.579  1.00 44.68  ? 6   TYR D N   1 
ATOM   10412 C CA  . TYR D 1 6   ? -51.376 -10.231 17.365  1.00 43.48  ? 6   TYR D CA  1 
ATOM   10413 C C   . TYR D 1 6   ? -52.740 -9.565  17.511  1.00 47.69  ? 6   TYR D C   1 
ATOM   10414 O O   . TYR D 1 6   ? -53.521 -9.582  16.540  1.00 48.56  ? 6   TYR D O   1 
ATOM   10415 C CB  . TYR D 1 6   ? -50.450 -9.227  16.674  1.00 40.62  ? 6   TYR D CB  1 
ATOM   10416 C CG  . TYR D 1 6   ? -48.965 -9.558  16.631  1.00 46.59  ? 6   TYR D CG  1 
ATOM   10417 C CD1 . TYR D 1 6   ? -48.280 -9.960  17.770  1.00 44.69  ? 6   TYR D CD1 1 
ATOM   10418 C CD2 . TYR D 1 6   ? -48.242 -9.438  15.451  1.00 47.29  ? 6   TYR D CD2 1 
ATOM   10419 C CE1 . TYR D 1 6   ? -46.925 -10.246 17.733  1.00 41.76  ? 6   TYR D CE1 1 
ATOM   10420 C CE2 . TYR D 1 6   ? -46.888 -9.720  15.401  1.00 43.86  ? 6   TYR D CE2 1 
ATOM   10421 C CZ  . TYR D 1 6   ? -46.227 -10.126 16.545  1.00 42.57  ? 6   TYR D CZ  1 
ATOM   10422 O OH  . TYR D 1 6   ? -44.894 -10.410 16.501  1.00 40.27  ? 6   TYR D OH  1 
ATOM   10423 N N   . THR D 1 7   ? -53.029 -9.000  18.688  1.00 49.57  ? 7   THR D N   1 
ATOM   10424 C CA  . THR D 1 7   ? -54.263 -8.246  18.911  1.00 50.26  ? 7   THR D CA  1 
ATOM   10425 C C   . THR D 1 7   ? -53.926 -6.834  19.398  1.00 45.75  ? 7   THR D C   1 
ATOM   10426 O O   . THR D 1 7   ? -52.797 -6.546  19.744  1.00 44.67  ? 7   THR D O   1 
ATOM   10427 C CB  . THR D 1 7   ? -55.169 -8.990  19.912  1.00 58.20  ? 7   THR D CB  1 
ATOM   10428 O OG1 . THR D 1 7   ? -54.484 -9.045  21.167  1.00 61.16  ? 7   THR D OG1 1 
ATOM   10429 C CG2 . THR D 1 7   ? -55.515 -10.396 19.457  1.00 57.52  ? 7   THR D CG2 1 
ATOM   10430 N N   . ASP D 1 8   ? -54.943 -5.975  19.423  1.00 46.12  ? 8   ASP D N   1 
ATOM   10431 C CA  . ASP D 1 8   ? -54.816 -4.618  19.904  1.00 47.45  ? 8   ASP D CA  1 
ATOM   10432 C C   . ASP D 1 8   ? -53.810 -3.850  19.059  1.00 47.98  ? 8   ASP D C   1 
ATOM   10433 O O   . ASP D 1 8   ? -53.080 -3.015  19.581  1.00 49.94  ? 8   ASP D O   1 
ATOM   10434 C CB  . ASP D 1 8   ? -54.467 -4.605  21.373  1.00 56.87  ? 8   ASP D CB  1 
ATOM   10435 C CG  . ASP D 1 8   ? -55.514 -5.243  22.273  1.00 64.31  ? 8   ASP D CG  1 
ATOM   10436 O OD1 . ASP D 1 8   ? -56.578 -4.607  22.462  1.00 61.95  ? 8   ASP D OD1 1 
ATOM   10437 O OD2 . ASP D 1 8   ? -55.274 -6.393  22.742  1.00 66.79  ? 8   ASP D OD2 1 
ATOM   10438 N N   . LEU D 1 9   ? -53.837 -4.085  17.734  1.00 50.08  ? 9   LEU D N   1 
ATOM   10439 C CA  . LEU D 1 9   ? -52.885 -3.464  16.808  1.00 47.03  ? 9   LEU D CA  1 
ATOM   10440 C C   . LEU D 1 9   ? -53.080 -1.941  16.777  1.00 47.50  ? 9   LEU D C   1 
ATOM   10441 O O   . LEU D 1 9   ? -52.234 -1.227  16.265  1.00 44.44  ? 9   LEU D O   1 
ATOM   10442 C CB  . LEU D 1 9   ? -53.025 -4.052  15.403  1.00 45.08  ? 9   LEU D CB  1 
ATOM   10443 C CG  . LEU D 1 9   ? -52.228 -5.330  15.093  1.00 48.11  ? 9   LEU D CG  1 
ATOM   10444 C CD1 . LEU D 1 9   ? -50.842 -5.357  15.785  1.00 47.38  ? 9   LEU D CD1 1 
ATOM   10445 C CD2 . LEU D 1 9   ? -53.022 -6.555  15.445  1.00 52.74  ? 9   LEU D CD2 1 
ATOM   10446 N N   . GLY D 1 10  ? -54.216 -1.458  17.300  1.00 49.89  ? 10  GLY D N   1 
ATOM   10447 C CA  . GLY D 1 10  ? -54.527 -0.031  17.285  1.00 47.89  ? 10  GLY D CA  1 
ATOM   10448 C C   . GLY D 1 10  ? -53.649 0.760   18.256  1.00 44.29  ? 10  GLY D C   1 
ATOM   10449 O O   . GLY D 1 10  ? -53.490 1.972   18.106  1.00 45.58  ? 10  GLY D O   1 
ATOM   10450 N N   . LEU D 1 11  ? -53.081 0.057   19.242  1.00 42.75  ? 11  LEU D N   1 
ATOM   10451 C CA  . LEU D 1 11  ? -52.191 0.671   20.221  1.00 48.53  ? 11  LEU D CA  1 
ATOM   10452 C C   . LEU D 1 11  ? -50.901 1.110   19.530  1.00 49.94  ? 11  LEU D C   1 
ATOM   10453 O O   . LEU D 1 11  ? -50.373 0.401   18.679  1.00 55.44  ? 11  LEU D O   1 
ATOM   10454 C CB  . LEU D 1 11  ? -51.911 -0.303  21.380  1.00 47.71  ? 11  LEU D CB  1 
ATOM   10455 C CG  . LEU D 1 11  ? -53.086 -0.560  22.347  1.00 46.71  ? 11  LEU D CG  1 
ATOM   10456 C CD1 . LEU D 1 11  ? -52.684 -1.403  23.562  1.00 45.73  ? 11  LEU D CD1 1 
ATOM   10457 C CD2 . LEU D 1 11  ? -53.690 0.760   22.794  1.00 47.84  ? 11  LEU D CD2 1 
ATOM   10458 N N   . GLN D 1 12  ? -50.397 2.277   19.934  1.00 47.06  ? 12  GLN D N   1 
ATOM   10459 C CA  . GLN D 1 12  ? -49.205 2.856   19.350  1.00 46.42  ? 12  GLN D CA  1 
ATOM   10460 C C   . GLN D 1 12  ? -48.018 2.626   20.274  1.00 48.71  ? 12  GLN D C   1 
ATOM   10461 O O   . GLN D 1 12  ? -48.113 2.835   21.476  1.00 48.21  ? 12  GLN D O   1 
ATOM   10462 C CB  . GLN D 1 12  ? -49.383 4.353   19.129  1.00 47.66  ? 12  GLN D CB  1 
ATOM   10463 C CG  . GLN D 1 12  ? -50.281 4.709   17.959  1.00 47.43  ? 12  GLN D CG  1 
ATOM   10464 C CD  . GLN D 1 12  ? -50.177 6.165   17.565  1.00 51.21  ? 12  GLN D CD  1 
ATOM   10465 O OE1 . GLN D 1 12  ? -49.096 6.682   17.279  1.00 51.28  ? 12  GLN D OE1 1 
ATOM   10466 N NE2 . GLN D 1 12  ? -51.307 6.847   17.549  1.00 59.37  ? 12  GLN D NE2 1 
ATOM   10467 N N   . PRO D 1 13  ? -46.845 2.215   19.734  1.00 55.12  ? 13  PRO D N   1 
ATOM   10468 C CA  . PRO D 1 13  ? -45.609 2.204   20.512  1.00 45.84  ? 13  PRO D CA  1 
ATOM   10469 C C   . PRO D 1 13  ? -45.046 3.609   20.586  1.00 37.98  ? 13  PRO D C   1 
ATOM   10470 O O   . PRO D 1 13  ? -44.518 4.124   19.604  1.00 37.55  ? 13  PRO D O   1 
ATOM   10471 C CB  . PRO D 1 13  ? -44.697 1.210   19.733  1.00 45.59  ? 13  PRO D CB  1 
ATOM   10472 C CG  . PRO D 1 13  ? -45.180 1.306   18.297  1.00 45.98  ? 13  PRO D CG  1 
ATOM   10473 C CD  . PRO D 1 13  ? -46.659 1.721   18.360  1.00 48.67  ? 13  PRO D CD  1 
ATOM   10474 N N   . LEU D 1 14  ? -45.219 4.240   21.748  1.00 44.76  ? 14  LEU D N   1 
ATOM   10475 C CA  . LEU D 1 14  ? -44.748 5.610   21.980  1.00 42.22  ? 14  LEU D CA  1 
ATOM   10476 C C   . LEU D 1 14  ? -43.900 5.649   23.249  1.00 42.39  ? 14  LEU D C   1 
ATOM   10477 O O   . LEU D 1 14  ? -44.399 5.350   24.341  1.00 44.36  ? 14  LEU D O   1 
ATOM   10478 C CB  . LEU D 1 14  ? -45.943 6.535   22.106  1.00 40.66  ? 14  LEU D CB  1 
ATOM   10479 C CG  . LEU D 1 14  ? -46.788 6.713   20.851  1.00 42.76  ? 14  LEU D CG  1 
ATOM   10480 C CD1 . LEU D 1 14  ? -48.130 7.342   21.182  1.00 43.07  ? 14  LEU D CD1 1 
ATOM   10481 C CD2 . LEU D 1 14  ? -46.053 7.544   19.834  1.00 44.35  ? 14  LEU D CD2 1 
ATOM   10482 N N   . ALA D 1 15  ? -42.604 5.983   23.077  1.00 40.28  ? 15  ALA D N   1 
ATOM   10483 C CA  . ALA D 1 15  ? -41.670 6.205   24.183  1.00 40.44  ? 15  ALA D CA  1 
ATOM   10484 C C   . ALA D 1 15  ? -41.660 5.016   25.136  1.00 42.75  ? 15  ALA D C   1 
ATOM   10485 O O   . ALA D 1 15  ? -41.714 5.195   26.343  1.00 48.80  ? 15  ALA D O   1 
ATOM   10486 C CB  . ALA D 1 15  ? -42.022 7.487   24.907  1.00 37.93  ? 15  ALA D CB  1 
ATOM   10487 N N   . GLY D 1 16  ? -41.610 3.804   24.579  1.00 42.32  ? 16  GLY D N   1 
ATOM   10488 C CA  . GLY D 1 16  ? -41.369 2.608   25.366  1.00 42.19  ? 16  GLY D CA  1 
ATOM   10489 C C   . GLY D 1 16  ? -42.651 1.967   25.906  1.00 43.84  ? 16  GLY D C   1 
ATOM   10490 O O   . GLY D 1 16  ? -42.570 0.987   26.619  1.00 53.06  ? 16  GLY D O   1 
ATOM   10491 N N   . GLU D 1 17  ? -43.827 2.509   25.549  1.00 49.87  ? 17  GLU D N   1 
ATOM   10492 C CA  . GLU D 1 17  ? -45.098 1.941   26.017  1.00 56.96  ? 17  GLU D CA  1 
ATOM   10493 C C   . GLU D 1 17  ? -46.089 1.839   24.848  1.00 51.94  ? 17  GLU D C   1 
ATOM   10494 O O   . GLU D 1 17  ? -46.050 2.640   23.916  1.00 53.27  ? 17  GLU D O   1 
ATOM   10495 C CB  . GLU D 1 17  ? -45.688 2.761   27.179  1.00 64.23  ? 17  GLU D CB  1 
ATOM   10496 C CG  . GLU D 1 17  ? -46.164 4.150   26.759  1.00 73.86  ? 17  GLU D CG  1 
ATOM   10497 C CD  . GLU D 1 17  ? -46.070 5.243   27.821  1.00 79.43  ? 17  GLU D CD  1 
ATOM   10498 O OE1 . GLU D 1 17  ? -46.480 4.989   28.990  1.00 65.22  ? 17  GLU D OE1 1 
ATOM   10499 O OE2 . GLU D 1 17  ? -45.643 6.392   27.449  1.00 78.56  ? 17  GLU D OE2 1 
ATOM   10500 N N   . TRP D 1 18  ? -46.983 0.850   24.933  1.00 47.23  ? 18  TRP D N   1 
ATOM   10501 C CA  . TRP D 1 18  ? -48.068 0.696   23.980  1.00 50.29  ? 18  TRP D CA  1 
ATOM   10502 C C   . TRP D 1 18  ? -49.348 1.351   24.538  1.00 54.34  ? 18  TRP D C   1 
ATOM   10503 O O   . TRP D 1 18  ? -49.966 0.846   25.503  1.00 55.40  ? 18  TRP D O   1 
ATOM   10504 C CB  . TRP D 1 18  ? -48.278 -0.801  23.648  1.00 48.86  ? 18  TRP D CB  1 
ATOM   10505 C CG  . TRP D 1 18  ? -47.070 -1.448  23.018  1.00 50.29  ? 18  TRP D CG  1 
ATOM   10506 C CD1 . TRP D 1 18  ? -45.973 -1.948  23.658  1.00 43.75  ? 18  TRP D CD1 1 
ATOM   10507 C CD2 . TRP D 1 18  ? -46.826 -1.628  21.604  1.00 50.37  ? 18  TRP D CD2 1 
ATOM   10508 N NE1 . TRP D 1 18  ? -45.068 -2.435  22.743  1.00 49.29  ? 18  TRP D NE1 1 
ATOM   10509 C CE2 . TRP D 1 18  ? -45.562 -2.250  21.477  1.00 51.91  ? 18  TRP D CE2 1 
ATOM   10510 C CE3 . TRP D 1 18  ? -47.545 -1.335  20.447  1.00 46.94  ? 18  TRP D CE3 1 
ATOM   10511 C CZ2 . TRP D 1 18  ? -45.017 -2.582  20.235  1.00 46.47  ? 18  TRP D CZ2 1 
ATOM   10512 C CZ3 . TRP D 1 18  ? -47.002 -1.668  19.222  1.00 48.37  ? 18  TRP D CZ3 1 
ATOM   10513 C CH2 . TRP D 1 18  ? -45.754 -2.273  19.121  1.00 43.30  ? 18  TRP D CH2 1 
ATOM   10514 N N   . ARG D 1 19  ? -49.744 2.470   23.919  1.00 48.32  ? 19  ARG D N   1 
ATOM   10515 C CA  . ARG D 1 19  ? -50.842 3.281   24.421  1.00 46.19  ? 19  ARG D CA  1 
ATOM   10516 C C   . ARG D 1 19  ? -51.564 3.988   23.255  1.00 47.73  ? 19  ARG D C   1 
ATOM   10517 O O   . ARG D 1 19  ? -51.094 3.970   22.113  1.00 39.44  ? 19  ARG D O   1 
ATOM   10518 C CB  . ARG D 1 19  ? -50.292 4.296   25.439  1.00 44.74  ? 19  ARG D CB  1 
ATOM   10519 C CG  . ARG D 1 19  ? -49.426 5.406   24.840  1.00 45.35  ? 19  ARG D CG  1 
ATOM   10520 C CD  . ARG D 1 19  ? -49.327 6.577   25.772  1.00 46.17  ? 19  ARG D CD  1 
ATOM   10521 N NE  . ARG D 1 19  ? -48.239 7.504   25.463  1.00 42.89  ? 19  ARG D NE  1 
ATOM   10522 C CZ  . ARG D 1 19  ? -48.397 8.696   24.858  1.00 45.98  ? 19  ARG D CZ  1 
ATOM   10523 N NH1 . ARG D 1 19  ? -49.569 9.039   24.322  1.00 44.31  ? 19  ARG D NH1 1 
ATOM   10524 N NH2 . ARG D 1 19  ? -47.365 9.530   24.750  1.00 45.92  ? 19  ARG D NH2 1 
ATOM   10525 N N   . HIS D 1 20  ? -52.691 4.655   23.584  1.00 47.78  ? 20  HIS D N   1 
ATOM   10526 C CA  . HIS D 1 20  ? -53.390 5.520   22.650  1.00 48.19  ? 20  HIS D CA  1 
ATOM   10527 C C   . HIS D 1 20  ? -52.632 6.836   22.509  1.00 48.68  ? 20  HIS D C   1 
ATOM   10528 O O   . HIS D 1 20  ? -51.948 7.279   23.436  1.00 53.19  ? 20  HIS D O   1 
ATOM   10529 C CB  . HIS D 1 20  ? -54.839 5.801   23.102  1.00 51.56  ? 20  HIS D CB  1 
ATOM   10530 C CG  . HIS D 1 20  ? -55.670 4.576   23.445  1.00 64.43  ? 20  HIS D CG  1 
ATOM   10531 N ND1 . HIS D 1 20  ? -56.560 3.964   22.573  1.00 62.13  ? 20  HIS D ND1 1 
ATOM   10532 C CD2 . HIS D 1 20  ? -55.783 3.898   24.606  1.00 73.67  ? 20  HIS D CD2 1 
ATOM   10533 C CE1 . HIS D 1 20  ? -57.148 2.932   23.181  1.00 60.75  ? 20  HIS D CE1 1 
ATOM   10534 N NE2 . HIS D 1 20  ? -56.699 2.869   24.409  1.00 65.08  ? 20  HIS D NE2 1 
ATOM   10535 N N   . GLY D 1 21  ? -52.795 7.477   21.354  1.00 48.86  ? 21  GLY D N   1 
ATOM   10536 C CA  . GLY D 1 21  ? -52.326 8.835   21.158  1.00 53.58  ? 21  GLY D CA  1 
ATOM   10537 C C   . GLY D 1 21  ? -53.282 9.838   21.804  1.00 57.68  ? 21  GLY D C   1 
ATOM   10538 O O   . GLY D 1 21  ? -54.470 9.554   21.976  1.00 56.60  ? 21  GLY D O   1 
ATOM   10539 N N   . ARG D 1 22  ? -52.765 11.032  22.093  1.00 59.78  ? 22  ARG D N   1 
ATOM   10540 C CA  . ARG D 1 22  ? -53.482 12.009  22.905  1.00 60.09  ? 22  ARG D CA  1 
ATOM   10541 C C   . ARG D 1 22  ? -54.088 13.113  22.028  1.00 58.76  ? 22  ARG D C   1 
ATOM   10542 O O   . ARG D 1 22  ? -54.551 14.118  22.544  1.00 63.64  ? 22  ARG D O   1 
ATOM   10543 C CB  . ARG D 1 22  ? -52.531 12.628  23.941  1.00 54.75  ? 22  ARG D CB  1 
ATOM   10544 C CG  . ARG D 1 22  ? -51.692 11.614  24.702  1.00 52.93  ? 22  ARG D CG  1 
ATOM   10545 C CD  . ARG D 1 22  ? -52.102 11.462  26.153  1.00 54.51  ? 22  ARG D CD  1 
ATOM   10546 N NE  . ARG D 1 22  ? -51.296 10.472  26.896  1.00 52.50  ? 22  ARG D NE  1 
ATOM   10547 C CZ  . ARG D 1 22  ? -50.015 10.636  27.298  1.00 52.58  ? 22  ARG D CZ  1 
ATOM   10548 N NH1 . ARG D 1 22  ? -49.322 11.746  26.973  1.00 54.06  ? 22  ARG D NH1 1 
ATOM   10549 N NH2 . ARG D 1 22  ? -49.430 9.684   28.004  1.00 48.95  ? 22  ARG D NH2 1 
ATOM   10550 N N   . ALA D 1 23  ? -54.089 12.928  20.708  1.00 60.39  ? 23  ALA D N   1 
ATOM   10551 C CA  . ALA D 1 23  ? -54.561 13.988  19.797  1.00 60.13  ? 23  ALA D CA  1 
ATOM   10552 C C   . ALA D 1 23  ? -56.067 14.272  19.996  1.00 54.91  ? 23  ALA D C   1 
ATOM   10553 O O   . ALA D 1 23  ? -56.540 15.345  19.671  1.00 49.28  ? 23  ALA D O   1 
ATOM   10554 C CB  . ALA D 1 23  ? -54.261 13.616  18.351  1.00 56.37  ? 23  ALA D CB  1 
ATOM   10555 N N   . GLY D 1 24  ? -56.815 13.266  20.431  1.00 57.91  ? 24  GLY D N   1 
ATOM   10556 C CA  . GLY D 1 24  ? -58.234 13.423  20.681  1.00 59.91  ? 24  GLY D CA  1 
ATOM   10557 C C   . GLY D 1 24  ? -59.092 13.082  19.456  1.00 68.18  ? 24  GLY D C   1 
ATOM   10558 O O   . GLY D 1 24  ? -60.306 13.242  19.509  1.00 67.56  ? 24  GLY D O   1 
ATOM   10559 N N   . ARG D 1 25  ? -58.460 12.581  18.364  1.00 71.07  ? 25  ARG D N   1 
ATOM   10560 C CA  . ARG D 1 25  ? -59.200 12.168  17.165  1.00 69.25  ? 25  ARG D CA  1 
ATOM   10561 C C   . ARG D 1 25  ? -58.963 10.678  16.883  1.00 67.22  ? 25  ARG D C   1 
ATOM   10562 O O   . ARG D 1 25  ? -57.909 10.147  17.204  1.00 73.56  ? 25  ARG D O   1 
ATOM   10563 C CB  . ARG D 1 25  ? -58.802 12.987  15.937  1.00 76.11  ? 25  ARG D CB  1 
ATOM   10564 C CG  . ARG D 1 25  ? -58.537 14.463  16.212  1.00 86.51  ? 25  ARG D CG  1 
ATOM   10565 C CD  . ARG D 1 25  ? -59.071 15.356  15.106  1.00 93.23  ? 25  ARG D CD  1 
ATOM   10566 N NE  . ARG D 1 25  ? -58.939 14.743  13.777  1.00 92.97  ? 25  ARG D NE  1 
ATOM   10567 C CZ  . ARG D 1 25  ? -58.107 15.148  12.829  1.00 101.72 ? 25  ARG D CZ  1 
ATOM   10568 N NH1 . ARG D 1 25  ? -57.341 16.217  13.023  1.00 101.00 ? 25  ARG D NH1 1 
ATOM   10569 N NH2 . ARG D 1 25  ? -58.062 14.499  11.671  1.00 104.68 ? 25  ARG D NH2 1 
ATOM   10570 N N   . ARG D 1 26  ? -59.968 10.025  16.264  1.00 58.61  ? 26  ARG D N   1 
ATOM   10571 C CA  . ARG D 1 26  ? -59.879 8.620   15.888  1.00 58.48  ? 26  ARG D CA  1 
ATOM   10572 C C   . ARG D 1 26  ? -59.610 8.509   14.393  1.00 57.23  ? 26  ARG D C   1 
ATOM   10573 O O   . ARG D 1 26  ? -60.144 9.279   13.605  1.00 61.84  ? 26  ARG D O   1 
ATOM   10574 C CB  . ARG D 1 26  ? -61.163 7.852   16.194  1.00 61.27  ? 26  ARG D CB  1 
ATOM   10575 C CG  . ARG D 1 26  ? -61.614 7.922   17.642  1.00 70.47  ? 26  ARG D CG  1 
ATOM   10576 C CD  . ARG D 1 26  ? -62.397 6.668   18.067  1.00 76.96  ? 26  ARG D CD  1 
ATOM   10577 N NE  . ARG D 1 26  ? -61.551 5.754   18.851  1.00 80.40  ? 26  ARG D NE  1 
ATOM   10578 C CZ  . ARG D 1 26  ? -61.816 4.485   19.152  1.00 79.40  ? 26  ARG D CZ  1 
ATOM   10579 N NH1 . ARG D 1 26  ? -62.883 3.879   18.659  1.00 87.17  ? 26  ARG D NH1 1 
ATOM   10580 N NH2 . ARG D 1 26  ? -60.992 3.818   19.932  1.00 80.35  ? 26  ARG D NH2 1 
ATOM   10581 N N   . LEU D 1 27  ? -58.759 7.547   14.022  1.00 58.10  ? 27  LEU D N   1 
ATOM   10582 C CA  . LEU D 1 27  ? -58.517 7.207   12.623  1.00 52.94  ? 27  LEU D CA  1 
ATOM   10583 C C   . LEU D 1 27  ? -59.114 5.825   12.338  1.00 48.04  ? 27  LEU D C   1 
ATOM   10584 O O   . LEU D 1 27  ? -58.862 4.859   13.079  1.00 51.00  ? 27  LEU D O   1 
ATOM   10585 C CB  . LEU D 1 27  ? -57.007 7.252   12.355  1.00 49.16  ? 27  LEU D CB  1 
ATOM   10586 C CG  . LEU D 1 27  ? -56.533 6.680   11.012  1.00 51.54  ? 27  LEU D CG  1 
ATOM   10587 C CD1 . LEU D 1 27  ? -57.131 7.456   9.859   1.00 48.54  ? 27  LEU D CD1 1 
ATOM   10588 C CD2 . LEU D 1 27  ? -54.996 6.654   10.911  1.00 48.10  ? 27  LEU D CD2 1 
ATOM   10589 N N   . LYS D 1 28  ? -59.889 5.729   11.264  1.00 45.27  ? 28  LYS D N   1 
ATOM   10590 C CA  . LYS D 1 28  ? -60.421 4.440   10.823  1.00 52.79  ? 28  LYS D CA  1 
ATOM   10591 C C   . LYS D 1 28  ? -59.480 3.834   9.779   1.00 50.88  ? 28  LYS D C   1 
ATOM   10592 O O   . LYS D 1 28  ? -58.999 4.546   8.884   1.00 46.06  ? 28  LYS D O   1 
ATOM   10593 C CB  . LYS D 1 28  ? -61.843 4.579   10.270  1.00 52.70  ? 28  LYS D CB  1 
ATOM   10594 C CG  . LYS D 1 28  ? -62.898 4.785   11.330  1.00 65.68  ? 28  LYS D CG  1 
ATOM   10595 C CD  . LYS D 1 28  ? -64.321 4.904   10.798  1.00 76.84  ? 28  LYS D CD  1 
ATOM   10596 C CE  . LYS D 1 28  ? -65.296 5.409   11.841  1.00 82.82  ? 28  LYS D CE  1 
ATOM   10597 N NZ  . LYS D 1 28  ? -66.408 6.136   11.221  1.00 88.97  ? 28  LYS D NZ  1 
ATOM   10598 N N   . VAL D 1 29  ? -59.208 2.519   9.921   1.00 43.46  ? 29  VAL D N   1 
ATOM   10599 C CA  . VAL D 1 29  ? -58.389 1.799   8.964   1.00 41.46  ? 29  VAL D CA  1 
ATOM   10600 C C   . VAL D 1 29  ? -59.268 0.769   8.279   1.00 37.26  ? 29  VAL D C   1 
ATOM   10601 O O   . VAL D 1 29  ? -59.792 -0.124  8.930   1.00 32.29  ? 29  VAL D O   1 
ATOM   10602 C CB  . VAL D 1 29  ? -57.149 1.133   9.596   1.00 40.83  ? 29  VAL D CB  1 
ATOM   10603 C CG1 . VAL D 1 29  ? -56.156 0.701   8.532   1.00 41.54  ? 29  VAL D CG1 1 
ATOM   10604 C CG2 . VAL D 1 29  ? -56.474 2.032   10.622  1.00 41.41  ? 29  VAL D CG2 1 
ATOM   10605 N N   . SER D 1 30  ? -59.372 0.886   6.952   1.00 39.81  ? 30  SER D N   1 
ATOM   10606 C CA  . SER D 1 30  ? -60.382 0.184   6.179   1.00 43.48  ? 30  SER D CA  1 
ATOM   10607 C C   . SER D 1 30  ? -59.736 -0.661  5.070   1.00 39.20  ? 30  SER D C   1 
ATOM   10608 O O   . SER D 1 30  ? -58.659 -0.354  4.588   1.00 41.38  ? 30  SER D O   1 
ATOM   10609 C CB  . SER D 1 30  ? -61.347 1.141   5.616   1.00 44.08  ? 30  SER D CB  1 
ATOM   10610 O OG  . SER D 1 30  ? -61.721 2.089   6.597   1.00 55.88  ? 30  SER D OG  1 
ATOM   10611 N N   . ASN D 1 31  ? -60.440 -1.706  4.674   1.00 36.19  ? 31  ASN D N   1 
ATOM   10612 C CA  . ASN D 1 31  ? -60.062 -2.542  3.551   1.00 33.54  ? 31  ASN D CA  1 
ATOM   10613 C C   . ASN D 1 31  ? -60.476 -1.852  2.252   1.00 33.76  ? 31  ASN D C   1 
ATOM   10614 O O   . ASN D 1 31  ? -61.636 -1.541  2.067   1.00 34.08  ? 31  ASN D O   1 
ATOM   10615 C CB  . ASN D 1 31  ? -60.707 -3.905  3.682   1.00 31.03  ? 31  ASN D CB  1 
ATOM   10616 C CG  . ASN D 1 31  ? -60.165 -4.900  2.705   1.00 31.68  ? 31  ASN D CG  1 
ATOM   10617 O OD1 . ASN D 1 31  ? -59.986 -4.589  1.516   1.00 29.18  ? 31  ASN D OD1 1 
ATOM   10618 N ND2 . ASN D 1 31  ? -59.932 -6.112  3.170   1.00 31.33  ? 31  ASN D ND2 1 
ATOM   10619 N N   . PRO D 1 32  ? -59.545 -1.595  1.306   1.00 35.86  ? 32  PRO D N   1 
ATOM   10620 C CA  . PRO D 1 32  ? -59.909 -0.958  0.038   1.00 35.43  ? 32  PRO D CA  1 
ATOM   10621 C C   . PRO D 1 32  ? -60.851 -1.771  -0.849  1.00 34.79  ? 32  PRO D C   1 
ATOM   10622 O O   . PRO D 1 32  ? -61.492 -1.210  -1.709  1.00 37.57  ? 32  PRO D O   1 
ATOM   10623 C CB  . PRO D 1 32  ? -58.520 -0.722  -0.669  1.00 37.12  ? 32  PRO D CB  1 
ATOM   10624 C CG  . PRO D 1 32  ? -57.499 -0.877  0.427   1.00 38.77  ? 32  PRO D CG  1 
ATOM   10625 C CD  . PRO D 1 32  ? -58.095 -1.829  1.435   1.00 37.00  ? 32  PRO D CD  1 
ATOM   10626 N N   . PHE D 1 33  ? -60.861 -3.110  -0.680  1.00 33.74  ? 33  PHE D N   1 
ATOM   10627 C CA  . PHE D 1 33  ? -61.670 -3.983  -1.514  1.00 36.97  ? 33  PHE D CA  1 
ATOM   10628 C C   . PHE D 1 33  ? -63.165 -3.796  -1.188  1.00 42.01  ? 33  PHE D C   1 
ATOM   10629 O O   . PHE D 1 33  ? -63.923 -3.315  -2.024  1.00 52.61  ? 33  PHE D O   1 
ATOM   10630 C CB  . PHE D 1 33  ? -61.260 -5.457  -1.378  1.00 37.66  ? 33  PHE D CB  1 
ATOM   10631 C CG  . PHE D 1 33  ? -61.987 -6.356  -2.366  1.00 40.34  ? 33  PHE D CG  1 
ATOM   10632 C CD1 . PHE D 1 33  ? -61.796 -6.197  -3.756  1.00 40.54  ? 33  PHE D CD1 1 
ATOM   10633 C CD2 . PHE D 1 33  ? -62.907 -7.302  -1.932  1.00 37.84  ? 33  PHE D CD2 1 
ATOM   10634 C CE1 . PHE D 1 33  ? -62.517 -6.956  -4.673  1.00 37.18  ? 33  PHE D CE1 1 
ATOM   10635 C CE2 . PHE D 1 33  ? -63.610 -8.077  -2.861  1.00 38.61  ? 33  PHE D CE2 1 
ATOM   10636 C CZ  . PHE D 1 33  ? -63.398 -7.905  -4.233  1.00 36.16  ? 33  PHE D CZ  1 
ATOM   10637 N N   . ASP D 1 34  ? -63.591 -4.245  0.002   1.00 44.84  ? 34  ASP D N   1 
ATOM   10638 C CA  . ASP D 1 34  ? -65.017 -4.293  0.341   1.00 39.92  ? 34  ASP D CA  1 
ATOM   10639 C C   . ASP D 1 34  ? -65.402 -3.152  1.283   1.00 36.12  ? 34  ASP D C   1 
ATOM   10640 O O   . ASP D 1 34  ? -66.556 -3.015  1.628   1.00 39.83  ? 34  ASP D O   1 
ATOM   10641 C CB  . ASP D 1 34  ? -65.396 -5.639  0.943   1.00 39.45  ? 34  ASP D CB  1 
ATOM   10642 C CG  . ASP D 1 34  ? -64.522 -6.111  2.087   1.00 41.07  ? 34  ASP D CG  1 
ATOM   10643 O OD1 . ASP D 1 34  ? -64.269 -7.347  2.158   1.00 43.94  ? 34  ASP D OD1 1 
ATOM   10644 O OD2 . ASP D 1 34  ? -64.041 -5.229  2.862   1.00 38.52  ? 34  ASP D OD2 1 
ATOM   10645 N N   . GLY D 1 35  ? -64.422 -2.379  1.754   1.00 39.75  ? 35  GLY D N   1 
ATOM   10646 C CA  . GLY D 1 35  ? -64.698 -1.194  2.592   1.00 36.29  ? 35  GLY D CA  1 
ATOM   10647 C C   . GLY D 1 35  ? -64.841 -1.537  4.097   1.00 39.38  ? 35  GLY D C   1 
ATOM   10648 O O   . GLY D 1 35  ? -65.141 -0.668  4.908   1.00 43.13  ? 35  GLY D O   1 
ATOM   10649 N N   . SER D 1 36  ? -64.572 -2.789  4.467   1.00 38.95  ? 36  SER D N   1 
ATOM   10650 C CA  . SER D 1 36  ? -64.801 -3.244  5.826   1.00 39.22  ? 36  SER D CA  1 
ATOM   10651 C C   . SER D 1 36  ? -63.787 -2.615  6.785   1.00 39.30  ? 36  SER D C   1 
ATOM   10652 O O   . SER D 1 36  ? -62.655 -2.337  6.417   1.00 38.97  ? 36  SER D O   1 
ATOM   10653 C CB  . SER D 1 36  ? -64.781 -4.769  5.899   1.00 41.12  ? 36  SER D CB  1 
ATOM   10654 O OG  . SER D 1 36  ? -63.536 -5.294  5.483   1.00 46.03  ? 36  SER D OG  1 
ATOM   10655 N N   . LEU D 1 37  ? -64.220 -2.415  8.029   1.00 44.18  ? 37  LEU D N   1 
ATOM   10656 C CA  . LEU D 1 37  ? -63.413 -1.763  9.056   1.00 44.03  ? 37  LEU D CA  1 
ATOM   10657 C C   . LEU D 1 37  ? -62.442 -2.756  9.645   1.00 44.22  ? 37  LEU D C   1 
ATOM   10658 O O   . LEU D 1 37  ? -62.858 -3.732  10.253  1.00 50.73  ? 37  LEU D O   1 
ATOM   10659 C CB  . LEU D 1 37  ? -64.317 -1.206  10.150  1.00 47.25  ? 37  LEU D CB  1 
ATOM   10660 C CG  . LEU D 1 37  ? -63.608 -0.477  11.292  1.00 48.19  ? 37  LEU D CG  1 
ATOM   10661 C CD1 . LEU D 1 37  ? -63.016 0.864   10.799  1.00 45.35  ? 37  LEU D CD1 1 
ATOM   10662 C CD2 . LEU D 1 37  ? -64.557 -0.271  12.456  1.00 44.44  ? 37  LEU D CD2 1 
ATOM   10663 N N   . LEU D 1 38  ? -61.147 -2.474  9.509   1.00 43.38  ? 38  LEU D N   1 
ATOM   10664 C CA  . LEU D 1 38  ? -60.129 -3.356  10.044  1.00 44.77  ? 38  LEU D CA  1 
ATOM   10665 C C   . LEU D 1 38  ? -59.872 -3.011  11.501  1.00 45.30  ? 38  LEU D C   1 
ATOM   10666 O O   . LEU D 1 38  ? -59.857 -3.905  12.345  1.00 45.50  ? 38  LEU D O   1 
ATOM   10667 C CB  . LEU D 1 38  ? -58.854 -3.280  9.216   1.00 40.93  ? 38  LEU D CB  1 
ATOM   10668 C CG  . LEU D 1 38  ? -59.023 -3.607  7.737   1.00 39.12  ? 38  LEU D CG  1 
ATOM   10669 C CD1 . LEU D 1 38  ? -57.698 -3.512  7.037   1.00 37.19  ? 38  LEU D CD1 1 
ATOM   10670 C CD2 . LEU D 1 38  ? -59.660 -4.987  7.547   1.00 35.59  ? 38  LEU D CD2 1 
ATOM   10671 N N   . LEU D 1 39  ? -59.584 -1.728  11.777  1.00 43.60  ? 39  LEU D N   1 
ATOM   10672 C CA  . LEU D 1 39  ? -59.394 -1.284  13.148  1.00 45.94  ? 39  LEU D CA  1 
ATOM   10673 C C   . LEU D 1 39  ? -59.421 0.233   13.219  1.00 42.19  ? 39  LEU D C   1 
ATOM   10674 O O   . LEU D 1 39  ? -59.490 0.917   12.190  1.00 42.52  ? 39  LEU D O   1 
ATOM   10675 C CB  . LEU D 1 39  ? -58.101 -1.857  13.757  1.00 54.46  ? 39  LEU D CB  1 
ATOM   10676 C CG  . LEU D 1 39  ? -56.784 -1.177  13.376  1.00 59.75  ? 39  LEU D CG  1 
ATOM   10677 C CD1 . LEU D 1 39  ? -55.802 -1.386  14.477  1.00 61.78  ? 39  LEU D CD1 1 
ATOM   10678 C CD2 . LEU D 1 39  ? -56.218 -1.704  12.058  1.00 68.37  ? 39  LEU D CD2 1 
ATOM   10679 N N   . GLU D 1 40  ? -59.402 0.740   14.466  1.00 44.40  ? 40  GLU D N   1 
ATOM   10680 C CA  . GLU D 1 40  ? -59.484 2.166   14.747  1.00 47.82  ? 40  GLU D CA  1 
ATOM   10681 C C   . GLU D 1 40  ? -58.311 2.563   15.644  1.00 45.20  ? 40  GLU D C   1 
ATOM   10682 O O   . GLU D 1 40  ? -57.939 1.801   16.550  1.00 40.60  ? 40  GLU D O   1 
ATOM   10683 C CB  . GLU D 1 40  ? -60.826 2.479   15.418  1.00 56.47  ? 40  GLU D CB  1 
ATOM   10684 C CG  . GLU D 1 40  ? -61.761 3.346   14.569  1.00 64.55  ? 40  GLU D CG  1 
ATOM   10685 C CD  . GLU D 1 40  ? -63.194 3.439   15.094  1.00 71.36  ? 40  GLU D CD  1 
ATOM   10686 O OE1 . GLU D 1 40  ? -63.399 4.093   16.134  1.00 74.90  ? 40  GLU D OE1 1 
ATOM   10687 O OE2 . GLU D 1 40  ? -64.102 2.856   14.464  1.00 84.47  ? 40  GLU D OE2 1 
ATOM   10688 N N   . ILE D 1 41  ? -57.728 3.754   15.370  1.00 37.86  ? 41  ILE D N   1 
ATOM   10689 C CA  . ILE D 1 41  ? -56.558 4.248   16.085  1.00 41.59  ? 41  ILE D CA  1 
ATOM   10690 C C   . ILE D 1 41  ? -56.845 5.651   16.657  1.00 45.87  ? 41  ILE D C   1 
ATOM   10691 O O   . ILE D 1 41  ? -57.239 6.565   15.909  1.00 40.68  ? 41  ILE D O   1 
ATOM   10692 C CB  . ILE D 1 41  ? -55.328 4.306   15.164  1.00 45.26  ? 41  ILE D CB  1 
ATOM   10693 C CG1 . ILE D 1 41  ? -54.986 2.954   14.582  1.00 45.49  ? 41  ILE D CG1 1 
ATOM   10694 C CG2 . ILE D 1 41  ? -54.121 4.930   15.903  1.00 40.22  ? 41  ILE D CG2 1 
ATOM   10695 C CD1 . ILE D 1 41  ? -53.766 2.974   13.676  1.00 44.31  ? 41  ILE D CD1 1 
ATOM   10696 N N   . GLU D 1 42  ? -56.500 5.845   17.955  1.00 43.49  ? 42  GLU D N   1 
ATOM   10697 C CA  . GLU D 1 42  ? -56.481 7.165   18.577  1.00 42.50  ? 42  GLU D CA  1 
ATOM   10698 C C   . GLU D 1 42  ? -55.215 7.895   18.146  1.00 43.00  ? 42  GLU D C   1 
ATOM   10699 O O   . GLU D 1 42  ? -54.119 7.496   18.515  1.00 47.01  ? 42  GLU D O   1 
ATOM   10700 C CB  . GLU D 1 42  ? -56.514 7.057   20.102  1.00 47.37  ? 42  GLU D CB  1 
ATOM   10701 C CG  . GLU D 1 42  ? -57.798 6.431   20.656  1.00 49.26  ? 42  GLU D CG  1 
ATOM   10702 C CD  . GLU D 1 42  ? -59.058 7.320   20.659  1.00 58.37  ? 42  GLU D CD  1 
ATOM   10703 O OE1 . GLU D 1 42  ? -58.968 8.574   20.470  1.00 61.65  ? 42  GLU D OE1 1 
ATOM   10704 O OE2 . GLU D 1 42  ? -60.158 6.733   20.853  1.00 66.59  ? 42  GLU D OE2 1 
ATOM   10705 N N   . GLN D 1 43  ? -55.385 8.966   17.360  1.00 42.00  ? 43  GLN D N   1 
ATOM   10706 C CA  . GLN D 1 43  ? -54.278 9.637   16.711  1.00 44.67  ? 43  GLN D CA  1 
ATOM   10707 C C   . GLN D 1 43  ? -53.348 10.252  17.753  1.00 51.88  ? 43  GLN D C   1 
ATOM   10708 O O   . GLN D 1 43  ? -53.739 10.488  18.891  1.00 61.70  ? 43  GLN D O   1 
ATOM   10709 C CB  . GLN D 1 43  ? -54.782 10.694  15.737  1.00 50.37  ? 43  GLN D CB  1 
ATOM   10710 C CG  . GLN D 1 43  ? -55.674 10.127  14.638  1.00 58.25  ? 43  GLN D CG  1 
ATOM   10711 C CD  . GLN D 1 43  ? -55.546 10.861  13.325  1.00 60.52  ? 43  GLN D CD  1 
ATOM   10712 O OE1 . GLN D 1 43  ? -54.481 10.880  12.696  1.00 70.32  ? 43  GLN D OE1 1 
ATOM   10713 N NE2 . GLN D 1 43  ? -56.647 11.455  12.883  1.00 68.61  ? 43  GLN D NE2 1 
ATOM   10714 N N   . ALA D 1 44  ? -52.108 10.517  17.331  1.00 51.50  ? 44  ALA D N   1 
ATOM   10715 C CA  . ALA D 1 44  ? -51.091 11.041  18.208  1.00 48.45  ? 44  ALA D CA  1 
ATOM   10716 C C   . ALA D 1 44  ? -50.928 12.526  17.951  1.00 48.30  ? 44  ALA D C   1 
ATOM   10717 O O   . ALA D 1 44  ? -51.034 12.977  16.811  1.00 47.44  ? 44  ALA D O   1 
ATOM   10718 C CB  . ALA D 1 44  ? -49.799 10.304  17.982  1.00 51.95  ? 44  ALA D CB  1 
ATOM   10719 N N   . ASP D 1 45  ? -50.655 13.280  19.020  1.00 52.79  ? 45  ASP D N   1 
ATOM   10720 C CA  . ASP D 1 45  ? -50.445 14.722  18.913  1.00 61.01  ? 45  ASP D CA  1 
ATOM   10721 C C   . ASP D 1 45  ? -48.940 15.017  18.865  1.00 58.17  ? 45  ASP D C   1 
ATOM   10722 O O   . ASP D 1 45  ? -48.120 14.100  18.911  1.00 52.53  ? 45  ASP D O   1 
ATOM   10723 C CB  . ASP D 1 45  ? -51.146 15.473  20.045  1.00 60.10  ? 45  ASP D CB  1 
ATOM   10724 C CG  . ASP D 1 45  ? -50.557 15.274  21.436  1.00 65.00  ? 45  ASP D CG  1 
ATOM   10725 O OD1 . ASP D 1 45  ? -49.648 14.412  21.583  1.00 69.71  ? 45  ASP D OD1 1 
ATOM   10726 O OD2 . ASP D 1 45  ? -51.001 15.978  22.360  1.00 74.31  ? 45  ASP D OD2 1 
ATOM   10727 N N   . ARG D 1 46  ? -48.601 16.321  18.850  1.00 57.52  ? 46  ARG D N   1 
ATOM   10728 C CA  . ARG D 1 46  ? -47.221 16.780  18.752  1.00 55.82  ? 46  ARG D CA  1 
ATOM   10729 C C   . ARG D 1 46  ? -46.412 16.393  20.002  1.00 58.07  ? 46  ARG D C   1 
ATOM   10730 O O   . ARG D 1 46  ? -45.191 16.145  19.910  1.00 53.90  ? 46  ARG D O   1 
ATOM   10731 C CB  . ARG D 1 46  ? -47.190 18.292  18.566  1.00 57.23  ? 46  ARG D CB  1 
ATOM   10732 C CG  . ARG D 1 46  ? -45.874 18.951  18.966  1.00 69.96  ? 46  ARG D CG  1 
ATOM   10733 C CD  . ARG D 1 46  ? -44.860 18.965  17.837  1.00 75.57  ? 46  ARG D CD  1 
ATOM   10734 N NE  . ARG D 1 46  ? -45.420 19.667  16.680  1.00 86.30  ? 46  ARG D NE  1 
ATOM   10735 C CZ  . ARG D 1 46  ? -45.689 20.969  16.632  1.00 91.68  ? 46  ARG D CZ  1 
ATOM   10736 N NH1 . ARG D 1 46  ? -45.213 21.780  17.566  1.00 90.31  ? 46  ARG D NH1 1 
ATOM   10737 N NH2 . ARG D 1 46  ? -46.390 21.460  15.619  1.00 88.28  ? 46  ARG D NH2 1 
ATOM   10738 N N   . ASP D 1 47  ? -47.069 16.374  21.165  1.00 51.03  ? 47  ASP D N   1 
ATOM   10739 C CA  . ASP D 1 47  ? -46.391 16.017  22.396  1.00 55.69  ? 47  ASP D CA  1 
ATOM   10740 C C   . ASP D 1 47  ? -45.963 14.555  22.329  1.00 53.34  ? 47  ASP D C   1 
ATOM   10741 O O   . ASP D 1 47  ? -44.896 14.195  22.844  1.00 47.96  ? 47  ASP D O   1 
ATOM   10742 C CB  . ASP D 1 47  ? -47.252 16.271  23.625  1.00 67.31  ? 47  ASP D CB  1 
ATOM   10743 C CG  . ASP D 1 47  ? -47.617 17.719  23.890  1.00 71.47  ? 47  ASP D CG  1 
ATOM   10744 O OD1 . ASP D 1 47  ? -48.546 17.935  24.659  1.00 89.85  ? 47  ASP D OD1 1 
ATOM   10745 O OD2 . ASP D 1 47  ? -46.978 18.609  23.303  1.00 73.37  ? 47  ASP D OD2 1 
ATOM   10746 N N   . ASP D 1 48  ? -46.817 13.714  21.725  1.00 47.10  ? 48  ASP D N   1 
ATOM   10747 C CA  . ASP D 1 48  ? -46.498 12.309  21.529  1.00 48.06  ? 48  ASP D CA  1 
ATOM   10748 C C   . ASP D 1 48  ? -45.229 12.175  20.668  1.00 42.90  ? 48  ASP D C   1 
ATOM   10749 O O   . ASP D 1 48  ? -44.348 11.366  20.968  1.00 38.25  ? 48  ASP D O   1 
ATOM   10750 C CB  . ASP D 1 48  ? -47.696 11.547  20.985  1.00 52.86  ? 48  ASP D CB  1 
ATOM   10751 C CG  . ASP D 1 48  ? -48.807 11.275  21.998  1.00 53.72  ? 48  ASP D CG  1 
ATOM   10752 O OD1 . ASP D 1 48  ? -48.499 11.236  23.215  1.00 56.87  ? 48  ASP D OD1 1 
ATOM   10753 O OD2 . ASP D 1 48  ? -49.967 11.136  21.572  1.00 47.83  ? 48  ASP D OD2 1 
ATOM   10754 N N   . LEU D 1 49  ? -45.127 12.990  19.632  1.00 41.63  ? 49  LEU D N   1 
ATOM   10755 C CA  . LEU D 1 49  ? -43.966 12.957  18.763  1.00 44.62  ? 49  LEU D CA  1 
ATOM   10756 C C   . LEU D 1 49  ? -42.691 13.285  19.562  1.00 49.22  ? 49  LEU D C   1 
ATOM   10757 O O   . LEU D 1 49  ? -41.679 12.571  19.440  1.00 45.17  ? 49  LEU D O   1 
ATOM   10758 C CB  . LEU D 1 49  ? -44.179 13.930  17.604  1.00 46.21  ? 49  LEU D CB  1 
ATOM   10759 C CG  . LEU D 1 49  ? -42.949 14.241  16.751  1.00 44.85  ? 49  LEU D CG  1 
ATOM   10760 C CD1 . LEU D 1 49  ? -42.409 12.984  16.066  1.00 48.90  ? 49  LEU D CD1 1 
ATOM   10761 C CD2 . LEU D 1 49  ? -43.283 15.304  15.721  1.00 47.78  ? 49  LEU D CD2 1 
ATOM   10762 N N   . ASP D 1 50  ? -42.745 14.379  20.372  1.00 46.60  ? 50  ASP D N   1 
ATOM   10763 C CA  . ASP D 1 50  ? -41.592 14.841  21.146  1.00 40.15  ? 50  ASP D CA  1 
ATOM   10764 C C   . ASP D 1 50  ? -41.126 13.747  22.114  1.00 38.53  ? 50  ASP D C   1 
ATOM   10765 O O   . ASP D 1 50  ? -39.932 13.495  22.242  1.00 39.80  ? 50  ASP D O   1 
ATOM   10766 C CB  . ASP D 1 50  ? -41.901 16.134  21.865  1.00 42.45  ? 50  ASP D CB  1 
ATOM   10767 C CG  . ASP D 1 50  ? -42.106 17.346  20.959  1.00 50.04  ? 50  ASP D CG  1 
ATOM   10768 O OD1 . ASP D 1 50  ? -42.748 18.305  21.409  1.00 54.86  ? 50  ASP D OD1 1 
ATOM   10769 O OD2 . ASP D 1 50  ? -41.649 17.303  19.794  1.00 55.35  ? 50  ASP D OD2 1 
ATOM   10770 N N   . ALA D 1 51  ? -42.071 13.101  22.783  1.00 38.14  ? 51  ALA D N   1 
ATOM   10771 C CA  . ALA D 1 51  ? -41.752 12.044  23.734  1.00 42.80  ? 51  ALA D CA  1 
ATOM   10772 C C   . ALA D 1 51  ? -40.996 10.893  23.041  1.00 44.88  ? 51  ALA D C   1 
ATOM   10773 O O   . ALA D 1 51  ? -40.012 10.389  23.580  1.00 45.56  ? 51  ALA D O   1 
ATOM   10774 C CB  . ALA D 1 51  ? -43.020 11.551  24.402  1.00 41.43  ? 51  ALA D CB  1 
ATOM   10775 N N   . ALA D 1 52  ? -41.486 10.472  21.860  1.00 46.03  ? 52  ALA D N   1 
ATOM   10776 C CA  . ALA D 1 52  ? -40.930 9.312   21.148  1.00 46.12  ? 52  ALA D CA  1 
ATOM   10777 C C   . ALA D 1 52  ? -39.475 9.586   20.723  1.00 40.04  ? 52  ALA D C   1 
ATOM   10778 O O   . ALA D 1 52  ? -38.610 8.736   20.886  1.00 30.97  ? 52  ALA D O   1 
ATOM   10779 C CB  . ALA D 1 52  ? -41.800 8.968   19.949  1.00 42.96  ? 52  ALA D CB  1 
ATOM   10780 N N   . TYR D 1 53  ? -39.221 10.798  20.212  1.00 40.35  ? 53  TYR D N   1 
ATOM   10781 C CA  . TYR D 1 53  ? -37.884 11.193  19.792  1.00 38.07  ? 53  TYR D CA  1 
ATOM   10782 C C   . TYR D 1 53  ? -36.948 11.248  21.005  1.00 41.54  ? 53  TYR D C   1 
ATOM   10783 O O   . TYR D 1 53  ? -35.812 10.758  20.941  1.00 46.47  ? 53  TYR D O   1 
ATOM   10784 C CB  . TYR D 1 53  ? -37.923 12.539  19.066  1.00 36.80  ? 53  TYR D CB  1 
ATOM   10785 C CG  . TYR D 1 53  ? -37.992 12.453  17.551  1.00 37.72  ? 53  TYR D CG  1 
ATOM   10786 C CD1 . TYR D 1 53  ? -37.275 11.492  16.847  1.00 37.32  ? 53  TYR D CD1 1 
ATOM   10787 C CD2 . TYR D 1 53  ? -38.766 13.347  16.816  1.00 39.65  ? 53  TYR D CD2 1 
ATOM   10788 C CE1 . TYR D 1 53  ? -37.313 11.435  15.462  1.00 36.37  ? 53  TYR D CE1 1 
ATOM   10789 C CE2 . TYR D 1 53  ? -38.819 13.292  15.433  1.00 41.51  ? 53  TYR D CE2 1 
ATOM   10790 C CZ  . TYR D 1 53  ? -38.088 12.329  14.754  1.00 40.24  ? 53  TYR D CZ  1 
ATOM   10791 O OH  . TYR D 1 53  ? -38.151 12.259  13.386  1.00 42.49  ? 53  TYR D OH  1 
ATOM   10792 N N   . ALA D 1 54  ? -37.418 11.856  22.093  1.00 41.10  ? 54  ALA D N   1 
ATOM   10793 C CA  . ALA D 1 54  ? -36.622 11.981  23.314  1.00 45.20  ? 54  ALA D CA  1 
ATOM   10794 C C   . ALA D 1 54  ? -36.258 10.590  23.857  1.00 46.03  ? 54  ALA D C   1 
ATOM   10795 O O   . ALA D 1 54  ? -35.103 10.335  24.213  1.00 49.98  ? 54  ALA D O   1 
ATOM   10796 C CB  . ALA D 1 54  ? -37.379 12.807  24.366  1.00 43.77  ? 54  ALA D CB  1 
ATOM   10797 N N   . LYS D 1 55  ? -37.242 9.698   23.947  1.00 42.78  ? 55  LYS D N   1 
ATOM   10798 C CA  . LYS D 1 55  ? -36.986 8.378   24.507  1.00 47.67  ? 55  LYS D CA  1 
ATOM   10799 C C   . LYS D 1 55  ? -35.988 7.613   23.613  1.00 51.63  ? 55  LYS D C   1 
ATOM   10800 O O   . LYS D 1 55  ? -35.071 6.949   24.118  1.00 48.04  ? 55  LYS D O   1 
ATOM   10801 C CB  . LYS D 1 55  ? -38.268 7.573   24.681  1.00 48.10  ? 55  LYS D CB  1 
ATOM   10802 C CG  . LYS D 1 55  ? -38.121 6.415   25.640  1.00 56.67  ? 55  LYS D CG  1 
ATOM   10803 C CD  . LYS D 1 55  ? -37.869 6.864   27.082  1.00 62.27  ? 55  LYS D CD  1 
ATOM   10804 C CE  . LYS D 1 55  ? -37.422 5.759   27.979  1.00 67.85  ? 55  LYS D CE  1 
ATOM   10805 N NZ  . LYS D 1 55  ? -38.014 4.471   27.613  1.00 68.76  ? 55  LYS D NZ  1 
ATOM   10806 N N   . ALA D 1 56  ? -36.176 7.706   22.284  1.00 46.20  ? 56  ALA D N   1 
ATOM   10807 C CA  . ALA D 1 56  ? -35.288 7.038   21.354  1.00 49.55  ? 56  ALA D CA  1 
ATOM   10808 C C   . ALA D 1 56  ? -33.841 7.516   21.585  1.00 46.62  ? 56  ALA D C   1 
ATOM   10809 O O   . ALA D 1 56  ? -32.927 6.707   21.645  1.00 44.69  ? 56  ALA D O   1 
ATOM   10810 C CB  . ALA D 1 56  ? -35.756 7.272   19.928  1.00 50.34  ? 56  ALA D CB  1 
ATOM   10811 N N   . ALA D 1 57  ? -33.669 8.832   21.780  1.00 49.87  ? 57  ALA D N   1 
ATOM   10812 C CA  . ALA D 1 57  ? -32.349 9.431   22.028  1.00 48.61  ? 57  ALA D CA  1 
ATOM   10813 C C   . ALA D 1 57  ? -31.747 8.924   23.356  1.00 48.39  ? 57  ALA D C   1 
ATOM   10814 O O   . ALA D 1 57  ? -30.530 8.779   23.489  1.00 45.52  ? 57  ALA D O   1 
ATOM   10815 C CB  . ALA D 1 57  ? -32.467 10.939  22.023  1.00 42.66  ? 57  ALA D CB  1 
ATOM   10816 N N   . GLU D 1 58  ? -32.597 8.660   24.324  1.00 47.16  ? 58  GLU D N   1 
ATOM   10817 C CA  . GLU D 1 58  ? -32.136 8.339   25.660  1.00 52.73  ? 58  GLU D CA  1 
ATOM   10818 C C   . GLU D 1 58  ? -31.589 6.903   25.702  1.00 48.62  ? 58  GLU D C   1 
ATOM   10819 O O   . GLU D 1 58  ? -30.550 6.652   26.302  1.00 48.99  ? 58  GLU D O   1 
ATOM   10820 C CB  . GLU D 1 58  ? -33.283 8.585   26.645  1.00 55.47  ? 58  GLU D CB  1 
ATOM   10821 C CG  . GLU D 1 58  ? -32.979 8.138   28.063  1.00 59.42  ? 58  GLU D CG  1 
ATOM   10822 C CD  . GLU D 1 58  ? -34.219 7.836   28.867  1.00 66.28  ? 58  GLU D CD  1 
ATOM   10823 O OE1 . GLU D 1 58  ? -34.208 6.826   29.604  1.00 76.53  ? 58  GLU D OE1 1 
ATOM   10824 O OE2 . GLU D 1 58  ? -35.214 8.578   28.718  1.00 75.69  ? 58  GLU D OE2 1 
ATOM   10825 N N   . VAL D 1 59  ? -32.305 5.963   25.082  1.00 47.83  ? 59  VAL D N   1 
ATOM   10826 C CA  . VAL D 1 59  ? -32.008 4.526   25.248  1.00 45.96  ? 59  VAL D CA  1 
ATOM   10827 C C   . VAL D 1 59  ? -31.006 4.038   24.184  1.00 41.96  ? 59  VAL D C   1 
ATOM   10828 O O   . VAL D 1 59  ? -30.510 2.900   24.275  1.00 45.87  ? 59  VAL D O   1 
ATOM   10829 C CB  . VAL D 1 59  ? -33.285 3.675   25.195  1.00 47.39  ? 59  VAL D CB  1 
ATOM   10830 C CG1 . VAL D 1 59  ? -34.186 3.948   26.389  1.00 47.41  ? 59  VAL D CG1 1 
ATOM   10831 C CG2 . VAL D 1 59  ? -34.037 3.864   23.868  1.00 46.53  ? 59  VAL D CG2 1 
ATOM   10832 N N   . GLN D 1 60  ? -30.724 4.884   23.178  1.00 38.13  ? 60  GLN D N   1 
ATOM   10833 C CA  . GLN D 1 60  ? -29.928 4.476   22.028  1.00 44.09  ? 60  GLN D CA  1 
ATOM   10834 C C   . GLN D 1 60  ? -28.482 4.121   22.441  1.00 45.82  ? 60  GLN D C   1 
ATOM   10835 O O   . GLN D 1 60  ? -27.956 3.104   21.995  1.00 48.25  ? 60  GLN D O   1 
ATOM   10836 C CB  . GLN D 1 60  ? -29.977 5.550   20.941  1.00 45.20  ? 60  GLN D CB  1 
ATOM   10837 C CG  . GLN D 1 60  ? -29.101 5.245   19.734  1.00 44.21  ? 60  GLN D CG  1 
ATOM   10838 C CD  . GLN D 1 60  ? -27.688 5.773   19.865  1.00 46.28  ? 60  GLN D CD  1 
ATOM   10839 O OE1 . GLN D 1 60  ? -27.445 6.857   20.404  1.00 51.55  ? 60  GLN D OE1 1 
ATOM   10840 N NE2 . GLN D 1 60  ? -26.745 5.024   19.335  1.00 53.06  ? 60  GLN D NE2 1 
ATOM   10841 N N   . PRO D 1 61  ? -27.784 4.944   23.268  1.00 50.49  ? 61  PRO D N   1 
ATOM   10842 C CA  . PRO D 1 61  ? -26.394 4.655   23.643  1.00 49.86  ? 61  PRO D CA  1 
ATOM   10843 C C   . PRO D 1 61  ? -26.167 3.260   24.228  1.00 47.23  ? 61  PRO D C   1 
ATOM   10844 O O   . PRO D 1 61  ? -25.158 2.614   23.923  1.00 51.90  ? 61  PRO D O   1 
ATOM   10845 C CB  . PRO D 1 61  ? -26.095 5.770   24.674  1.00 49.76  ? 61  PRO D CB  1 
ATOM   10846 C CG  . PRO D 1 61  ? -26.959 6.917   24.220  1.00 49.38  ? 61  PRO D CG  1 
ATOM   10847 C CD  . PRO D 1 61  ? -28.259 6.223   23.831  1.00 53.89  ? 61  PRO D CD  1 
ATOM   10848 N N   . ALA D 1 62  ? -27.103 2.799   25.069  1.00 41.14  ? 62  ALA D N   1 
ATOM   10849 C CA  . ALA D 1 62  ? -26.988 1.471   25.677  1.00 39.94  ? 62  ALA D CA  1 
ATOM   10850 C C   . ALA D 1 62  ? -27.142 0.363   24.611  1.00 42.48  ? 62  ALA D C   1 
ATOM   10851 O O   . ALA D 1 62  ? -26.479 -0.666  24.685  1.00 42.26  ? 62  ALA D O   1 
ATOM   10852 C CB  . ALA D 1 62  ? -27.996 1.312   26.794  1.00 36.10  ? 62  ALA D CB  1 
ATOM   10853 N N   . TRP D 1 63  ? -28.019 0.592   23.622  1.00 43.52  ? 63  TRP D N   1 
ATOM   10854 C CA  . TRP D 1 63  ? -28.186 -0.338  22.512  1.00 40.97  ? 63  TRP D CA  1 
ATOM   10855 C C   . TRP D 1 63  ? -26.887 -0.424  21.697  1.00 39.62  ? 63  TRP D C   1 
ATOM   10856 O O   . TRP D 1 63  ? -26.402 -1.509  21.420  1.00 35.88  ? 63  TRP D O   1 
ATOM   10857 C CB  . TRP D 1 63  ? -29.383 0.106   21.659  1.00 42.55  ? 63  TRP D CB  1 
ATOM   10858 C CG  . TRP D 1 63  ? -29.575 -0.619  20.351  1.00 36.93  ? 63  TRP D CG  1 
ATOM   10859 C CD1 . TRP D 1 63  ? -29.538 -0.060  19.111  1.00 31.84  ? 63  TRP D CD1 1 
ATOM   10860 C CD2 . TRP D 1 63  ? -29.944 -2.003  20.163  1.00 32.32  ? 63  TRP D CD2 1 
ATOM   10861 N NE1 . TRP D 1 63  ? -29.849 -0.993  18.169  1.00 33.27  ? 63  TRP D NE1 1 
ATOM   10862 C CE2 . TRP D 1 63  ? -30.092 -2.197  18.781  1.00 31.14  ? 63  TRP D CE2 1 
ATOM   10863 C CE3 . TRP D 1 63  ? -30.168 -3.079  21.025  1.00 35.00  ? 63  TRP D CE3 1 
ATOM   10864 C CZ2 . TRP D 1 63  ? -30.414 -3.433  18.233  1.00 34.56  ? 63  TRP D CZ2 1 
ATOM   10865 C CZ3 . TRP D 1 63  ? -30.517 -4.300  20.492  1.00 39.11  ? 63  TRP D CZ3 1 
ATOM   10866 C CH2 . TRP D 1 63  ? -30.647 -4.473  19.109  1.00 38.56  ? 63  TRP D CH2 1 
ATOM   10867 N N   . ALA D 1 64  ? -26.300 0.735   21.380  1.00 44.53  ? 64  ALA D N   1 
ATOM   10868 C CA  . ALA D 1 64  ? -25.033 0.786   20.631  1.00 49.52  ? 64  ALA D CA  1 
ATOM   10869 C C   . ALA D 1 64  ? -23.875 0.145   21.441  1.00 51.00  ? 64  ALA D C   1 
ATOM   10870 O O   . ALA D 1 64  ? -22.942 -0.405  20.857  1.00 45.11  ? 64  ALA D O   1 
ATOM   10871 C CB  . ALA D 1 64  ? -24.715 2.228   20.243  1.00 42.96  ? 64  ALA D CB  1 
ATOM   10872 N N   . ALA D 1 65  ? -23.965 0.204   22.785  1.00 50.34  ? 65  ALA D N   1 
ATOM   10873 C CA  . ALA D 1 65  ? -22.895 -0.263  23.652  1.00 49.47  ? 65  ALA D CA  1 
ATOM   10874 C C   . ALA D 1 65  ? -22.821 -1.789  23.666  1.00 45.45  ? 65  ALA D C   1 
ATOM   10875 O O   . ALA D 1 65  ? -21.817 -2.342  24.073  1.00 54.87  ? 65  ALA D O   1 
ATOM   10876 C CB  . ALA D 1 65  ? -23.078 0.284   25.056  1.00 51.19  ? 65  ALA D CB  1 
ATOM   10877 N N   . LEU D 1 66  ? -23.893 -2.462  23.264  1.00 46.56  ? 66  LEU D N   1 
ATOM   10878 C CA  . LEU D 1 66  ? -23.914 -3.928  23.272  1.00 47.29  ? 66  LEU D CA  1 
ATOM   10879 C C   . LEU D 1 66  ? -22.908 -4.450  22.264  1.00 45.08  ? 66  LEU D C   1 
ATOM   10880 O O   . LEU D 1 66  ? -22.597 -3.785  21.307  1.00 46.34  ? 66  LEU D O   1 
ATOM   10881 C CB  . LEU D 1 66  ? -25.306 -4.465  22.956  1.00 50.24  ? 66  LEU D CB  1 
ATOM   10882 C CG  . LEU D 1 66  ? -26.396 -4.196  23.997  1.00 51.35  ? 66  LEU D CG  1 
ATOM   10883 C CD1 . LEU D 1 66  ? -27.729 -4.688  23.471  1.00 48.77  ? 66  LEU D CD1 1 
ATOM   10884 C CD2 . LEU D 1 66  ? -26.079 -4.841  25.339  1.00 49.45  ? 66  LEU D CD2 1 
ATOM   10885 N N   . GLY D 1 67  ? -22.454 -5.672  22.481  1.00 48.11  ? 67  GLY D N   1 
ATOM   10886 C CA  . GLY D 1 67  ? -21.611 -6.364  21.523  1.00 49.70  ? 67  GLY D CA  1 
ATOM   10887 C C   . GLY D 1 67  ? -22.359 -6.638  20.212  1.00 47.88  ? 67  GLY D C   1 
ATOM   10888 O O   . GLY D 1 67  ? -23.574 -6.695  20.192  1.00 42.46  ? 67  GLY D O   1 
ATOM   10889 N N   . PRO D 1 68  ? -21.643 -6.750  19.074  1.00 44.98  ? 68  PRO D N   1 
ATOM   10890 C CA  . PRO D 1 68  ? -22.284 -6.958  17.793  1.00 41.33  ? 68  PRO D CA  1 
ATOM   10891 C C   . PRO D 1 68  ? -23.180 -8.181  17.736  1.00 42.78  ? 68  PRO D C   1 
ATOM   10892 O O   . PRO D 1 68  ? -24.222 -8.148  17.092  1.00 45.80  ? 68  PRO D O   1 
ATOM   10893 C CB  . PRO D 1 68  ? -21.066 -7.072  16.867  1.00 43.88  ? 68  PRO D CB  1 
ATOM   10894 C CG  . PRO D 1 68  ? -20.054 -6.151  17.503  1.00 42.28  ? 68  PRO D CG  1 
ATOM   10895 C CD  . PRO D 1 68  ? -20.200 -6.474  18.948  1.00 44.70  ? 68  PRO D CD  1 
ATOM   10896 N N   . SER D 1 69  ? -22.775 -9.261  18.419  1.00 37.77  ? 69  SER D N   1 
ATOM   10897 C CA  . SER D 1 69  ? -23.548 -10.503 18.414  1.00 35.50  ? 69  SER D CA  1 
ATOM   10898 C C   . SER D 1 69  ? -24.924 -10.307 19.082  1.00 39.29  ? 69  SER D C   1 
ATOM   10899 O O   . SER D 1 69  ? -25.920 -10.923 18.664  1.00 44.50  ? 69  SER D O   1 
ATOM   10900 C CB  . SER D 1 69  ? -22.799 -11.596 19.051  1.00 36.00  ? 69  SER D CB  1 
ATOM   10901 O OG  . SER D 1 69  ? -21.667 -11.935 18.267  1.00 41.25  ? 69  SER D OG  1 
ATOM   10902 N N   . ALA D 1 70  ? -24.976 -9.432  20.101  1.00 36.48  ? 70  ALA D N   1 
ATOM   10903 C CA  . ALA D 1 70  ? -26.196 -9.180  20.833  1.00 34.26  ? 70  ALA D CA  1 
ATOM   10904 C C   . ALA D 1 70  ? -27.222 -8.520  19.913  1.00 37.77  ? 70  ALA D C   1 
ATOM   10905 O O   . ALA D 1 70  ? -28.400 -8.901  19.905  1.00 41.18  ? 70  ALA D O   1 
ATOM   10906 C CB  . ALA D 1 70  ? -25.904 -8.329  22.041  1.00 33.85  ? 70  ALA D CB  1 
ATOM   10907 N N   . ARG D 1 71  ? -26.777 -7.532  19.134  1.00 36.39  ? 71  ARG D N   1 
ATOM   10908 C CA  . ARG D 1 71  ? -27.689 -6.813  18.251  1.00 38.34  ? 71  ARG D CA  1 
ATOM   10909 C C   . ARG D 1 71  ? -28.095 -7.729  17.091  1.00 37.92  ? 71  ARG D C   1 
ATOM   10910 O O   . ARG D 1 71  ? -29.218 -7.689  16.638  1.00 41.58  ? 71  ARG D O   1 
ATOM   10911 C CB  . ARG D 1 71  ? -27.074 -5.520  17.735  1.00 38.97  ? 71  ARG D CB  1 
ATOM   10912 C CG  . ARG D 1 71  ? -26.960 -4.424  18.771  1.00 40.65  ? 71  ARG D CG  1 
ATOM   10913 C CD  . ARG D 1 71  ? -26.756 -3.022  18.125  1.00 42.04  ? 71  ARG D CD  1 
ATOM   10914 N NE  . ARG D 1 71  ? -25.479 -2.908  17.400  1.00 42.69  ? 71  ARG D NE  1 
ATOM   10915 C CZ  . ARG D 1 71  ? -24.282 -2.960  17.957  1.00 43.61  ? 71  ARG D CZ  1 
ATOM   10916 N NH1 . ARG D 1 71  ? -24.155 -2.955  19.256  1.00 53.48  ? 71  ARG D NH1 1 
ATOM   10917 N NH2 . ARG D 1 71  ? -23.228 -3.060  17.224  1.00 42.24  ? 71  ARG D NH2 1 
ATOM   10918 N N   . ALA D 1 72  ? -27.180 -8.581  16.656  1.00 36.71  ? 72  ALA D N   1 
ATOM   10919 C CA  . ALA D 1 72  ? -27.458 -9.500  15.567  1.00 38.40  ? 72  ALA D CA  1 
ATOM   10920 C C   . ALA D 1 72  ? -28.484 -10.546 16.013  1.00 39.34  ? 72  ALA D C   1 
ATOM   10921 O O   . ALA D 1 72  ? -29.263 -11.051 15.203  1.00 37.49  ? 72  ALA D O   1 
ATOM   10922 C CB  . ALA D 1 72  ? -26.159 -10.150 15.107  1.00 38.39  ? 72  ALA D CB  1 
ATOM   10923 N N   . ALA D 1 73  ? -28.456 -10.898 17.301  1.00 39.06  ? 73  ALA D N   1 
ATOM   10924 C CA  . ALA D 1 73  ? -29.357 -11.923 17.818  1.00 39.74  ? 73  ALA D CA  1 
ATOM   10925 C C   . ALA D 1 73  ? -30.827 -11.489 17.592  1.00 40.02  ? 73  ALA D C   1 
ATOM   10926 O O   . ALA D 1 73  ? -31.686 -12.312 17.244  1.00 36.01  ? 73  ALA D O   1 
ATOM   10927 C CB  . ALA D 1 73  ? -29.052 -12.191 19.311  1.00 34.99  ? 73  ALA D CB  1 
ATOM   10928 N N   . VAL D 1 74  ? -31.092 -10.180 17.765  1.00 35.63  ? 74  VAL D N   1 
ATOM   10929 C CA  . VAL D 1 74  ? -32.437 -9.654  17.619  1.00 39.50  ? 74  VAL D CA  1 
ATOM   10930 C C   . VAL D 1 74  ? -32.880 -9.800  16.157  1.00 37.27  ? 74  VAL D C   1 
ATOM   10931 O O   . VAL D 1 74  ? -33.982 -10.270 15.885  1.00 35.07  ? 74  VAL D O   1 
ATOM   10932 C CB  . VAL D 1 74  ? -32.504 -8.194  18.111  1.00 38.86  ? 74  VAL D CB  1 
ATOM   10933 C CG1 . VAL D 1 74  ? -33.825 -7.520  17.763  1.00 38.56  ? 74  VAL D CG1 1 
ATOM   10934 C CG2 . VAL D 1 74  ? -32.239 -8.110  19.620  1.00 39.50  ? 74  VAL D CG2 1 
ATOM   10935 N N   . LEU D 1 75  ? -31.997 -9.435  15.221  1.00 36.18  ? 75  LEU D N   1 
ATOM   10936 C CA  . LEU D 1 75  ? -32.318 -9.522  13.799  1.00 35.40  ? 75  LEU D CA  1 
ATOM   10937 C C   . LEU D 1 75  ? -32.613 -10.987 13.416  1.00 38.33  ? 75  LEU D C   1 
ATOM   10938 O O   . LEU D 1 75  ? -33.551 -11.263 12.659  1.00 33.89  ? 75  LEU D O   1 
ATOM   10939 C CB  . LEU D 1 75  ? -31.197 -8.943  12.947  1.00 33.44  ? 75  LEU D CB  1 
ATOM   10940 C CG  . LEU D 1 75  ? -31.268 -7.438  12.640  1.00 33.47  ? 75  LEU D CG  1 
ATOM   10941 C CD1 . LEU D 1 75  ? -32.527 -7.082  11.898  1.00 33.23  ? 75  LEU D CD1 1 
ATOM   10942 C CD2 . LEU D 1 75  ? -31.136 -6.604  13.893  1.00 33.94  ? 75  LEU D CD2 1 
ATOM   10943 N N   . TYR D 1 76  ? -31.817 -11.930 13.941  1.00 38.73  ? 76  TYR D N   1 
ATOM   10944 C CA  . TYR D 1 76  ? -32.019 -13.349 13.615  1.00 42.33  ? 76  TYR D CA  1 
ATOM   10945 C C   . TYR D 1 76  ? -33.377 -13.821 14.168  1.00 38.58  ? 76  TYR D C   1 
ATOM   10946 O O   . TYR D 1 76  ? -34.092 -14.609 13.535  1.00 38.35  ? 76  TYR D O   1 
ATOM   10947 C CB  . TYR D 1 76  ? -30.867 -14.186 14.179  1.00 40.11  ? 76  TYR D CB  1 
ATOM   10948 C CG  . TYR D 1 76  ? -29.610 -14.210 13.329  1.00 36.97  ? 76  TYR D CG  1 
ATOM   10949 C CD1 . TYR D 1 76  ? -29.662 -14.574 12.008  1.00 36.03  ? 76  TYR D CD1 1 
ATOM   10950 C CD2 . TYR D 1 76  ? -28.359 -13.891 13.870  1.00 37.93  ? 76  TYR D CD2 1 
ATOM   10951 C CE1 . TYR D 1 76  ? -28.518 -14.615 11.227  1.00 36.32  ? 76  TYR D CE1 1 
ATOM   10952 C CE2 . TYR D 1 76  ? -27.212 -13.921 13.102  1.00 33.88  ? 76  TYR D CE2 1 
ATOM   10953 C CZ  . TYR D 1 76  ? -27.292 -14.288 11.779  1.00 36.63  ? 76  TYR D CZ  1 
ATOM   10954 O OH  . TYR D 1 76  ? -26.184 -14.320 11.009  1.00 42.92  ? 76  TYR D OH  1 
ATOM   10955 N N   . LYS D 1 77  ? -33.715 -13.320 15.340  1.00 38.03  ? 77  LYS D N   1 
ATOM   10956 C CA  . LYS D 1 77  ? -34.960 -13.655 16.009  1.00 43.78  ? 77  LYS D CA  1 
ATOM   10957 C C   . LYS D 1 77  ? -36.170 -13.065 15.237  1.00 39.01  ? 77  LYS D C   1 
ATOM   10958 O O   . LYS D 1 77  ? -37.235 -13.664 15.200  1.00 34.71  ? 77  LYS D O   1 
ATOM   10959 C CB  . LYS D 1 77  ? -34.815 -13.140 17.438  1.00 49.14  ? 77  LYS D CB  1 
ATOM   10960 C CG  . LYS D 1 77  ? -34.494 -14.208 18.503  1.00 59.60  ? 77  LYS D CG  1 
ATOM   10961 C CD  . LYS D 1 77  ? -33.491 -13.814 19.626  1.00 84.10  ? 77  LYS D CD  1 
ATOM   10962 C CE  . LYS D 1 77  ? -33.738 -12.475 20.412  1.00 89.20  ? 77  LYS D CE  1 
ATOM   10963 N NZ  . LYS D 1 77  ? -34.981 -12.420 21.219  1.00 93.84  ? 77  LYS D NZ  1 
ATOM   10964 N N   . ALA D 1 78  ? -35.972 -11.926 14.568  1.00 35.58  ? 78  ALA D N   1 
ATOM   10965 C CA  . ALA D 1 78  ? -37.031 -11.320 13.769  1.00 33.62  ? 78  ALA D CA  1 
ATOM   10966 C C   . ALA D 1 78  ? -37.315 -12.158 12.520  1.00 34.53  ? 78  ALA D C   1 
ATOM   10967 O O   . ALA D 1 78  ? -38.462 -12.343 12.167  1.00 37.30  ? 78  ALA D O   1 
ATOM   10968 C CB  . ALA D 1 78  ? -36.674 -9.912  13.414  1.00 32.81  ? 78  ALA D CB  1 
ATOM   10969 N N   . VAL D 1 79  ? -36.264 -12.689 11.885  1.00 36.86  ? 79  VAL D N   1 
ATOM   10970 C CA  . VAL D 1 79  ? -36.416 -13.637 10.770  1.00 36.16  ? 79  VAL D CA  1 
ATOM   10971 C C   . VAL D 1 79  ? -37.310 -14.810 11.195  1.00 38.21  ? 79  VAL D C   1 
ATOM   10972 O O   . VAL D 1 79  ? -38.089 -15.337 10.411  1.00 40.61  ? 79  VAL D O   1 
ATOM   10973 C CB  . VAL D 1 79  ? -35.051 -14.158 10.304  1.00 36.68  ? 79  VAL D CB  1 
ATOM   10974 C CG1 . VAL D 1 79  ? -35.195 -15.137 9.136   1.00 34.67  ? 79  VAL D CG1 1 
ATOM   10975 C CG2 . VAL D 1 79  ? -34.093 -13.014 9.944   1.00 39.95  ? 79  VAL D CG2 1 
ATOM   10976 N N   . GLU D 1 80  ? -37.153 -15.222 12.426  1.00 44.88  ? 80  GLU D N   1 
ATOM   10977 C CA  . GLU D 1 80  ? -37.812 -16.405 12.948  1.00 46.52  ? 80  GLU D CA  1 
ATOM   10978 C C   . GLU D 1 80  ? -39.317 -16.117 13.110  1.00 43.70  ? 80  GLU D C   1 
ATOM   10979 O O   . GLU D 1 80  ? -40.155 -16.973 12.842  1.00 37.07  ? 80  GLU D O   1 
ATOM   10980 C CB  . GLU D 1 80  ? -37.131 -16.703 14.279  1.00 55.80  ? 80  GLU D CB  1 
ATOM   10981 C CG  . GLU D 1 80  ? -36.722 -18.149 14.478  1.00 71.35  ? 80  GLU D CG  1 
ATOM   10982 C CD  . GLU D 1 80  ? -36.186 -18.376 15.883  1.00 87.40  ? 80  GLU D CD  1 
ATOM   10983 O OE1 . GLU D 1 80  ? -36.281 -17.431 16.709  1.00 103.10 ? 80  GLU D OE1 1 
ATOM   10984 O OE2 . GLU D 1 80  ? -35.657 -19.464 16.149  1.00 101.13 ? 80  GLU D OE2 1 
ATOM   10985 N N   . VAL D 1 81  ? -39.641 -14.869 13.517  1.00 37.28  ? 81  VAL D N   1 
ATOM   10986 C CA  . VAL D 1 81  ? -41.014 -14.417 13.650  1.00 35.73  ? 81  VAL D CA  1 
ATOM   10987 C C   . VAL D 1 81  ? -41.649 -14.251 12.256  1.00 35.28  ? 81  VAL D C   1 
ATOM   10988 O O   . VAL D 1 81  ? -42.814 -14.535 12.069  1.00 32.93  ? 81  VAL D O   1 
ATOM   10989 C CB  . VAL D 1 81  ? -41.058 -13.107 14.440  1.00 39.20  ? 81  VAL D CB  1 
ATOM   10990 C CG1 . VAL D 1 81  ? -42.446 -12.514 14.458  1.00 41.82  ? 81  VAL D CG1 1 
ATOM   10991 C CG2 . VAL D 1 81  ? -40.547 -13.282 15.854  1.00 41.00  ? 81  VAL D CG2 1 
ATOM   10992 N N   . PHE D 1 82  ? -40.857 -13.820 11.273  1.00 34.28  ? 82  PHE D N   1 
ATOM   10993 C CA  . PHE D 1 82  ? -41.362 -13.678 9.925   1.00 33.23  ? 82  PHE D CA  1 
ATOM   10994 C C   . PHE D 1 82  ? -41.886 -15.024 9.432   1.00 35.06  ? 82  PHE D C   1 
ATOM   10995 O O   . PHE D 1 82  ? -42.884 -15.079 8.726   1.00 34.84  ? 82  PHE D O   1 
ATOM   10996 C CB  . PHE D 1 82  ? -40.285 -13.114 9.015   1.00 31.70  ? 82  PHE D CB  1 
ATOM   10997 C CG  . PHE D 1 82  ? -40.371 -11.600 8.813   1.00 35.05  ? 82  PHE D CG  1 
ATOM   10998 C CD1 . PHE D 1 82  ? -39.913 -10.721 9.782   1.00 36.76  ? 82  PHE D CD1 1 
ATOM   10999 C CD2 . PHE D 1 82  ? -40.836 -11.065 7.621   1.00 32.28  ? 82  PHE D CD2 1 
ATOM   11000 C CE1 . PHE D 1 82  ? -39.961 -9.358  9.579   1.00 35.53  ? 82  PHE D CE1 1 
ATOM   11001 C CE2 . PHE D 1 82  ? -40.894 -9.707  7.439   1.00 36.61  ? 82  PHE D CE2 1 
ATOM   11002 C CZ  . PHE D 1 82  ? -40.460 -8.856  8.417   1.00 36.07  ? 82  PHE D CZ  1 
ATOM   11003 N N   . ASP D 1 83  ? -41.195 -16.105 9.797   1.00 37.02  ? 83  ASP D N   1 
ATOM   11004 C CA  . ASP D 1 83  ? -41.552 -17.439 9.328   1.00 37.26  ? 83  ASP D CA  1 
ATOM   11005 C C   . ASP D 1 83  ? -42.788 -17.958 10.062  1.00 38.13  ? 83  ASP D C   1 
ATOM   11006 O O   . ASP D 1 83  ? -43.638 -18.585 9.449   1.00 37.31  ? 83  ASP D O   1 
ATOM   11007 C CB  . ASP D 1 83  ? -40.386 -18.391 9.446   1.00 36.07  ? 83  ASP D CB  1 
ATOM   11008 C CG  . ASP D 1 83  ? -39.311 -18.202 8.396   1.00 38.91  ? 83  ASP D CG  1 
ATOM   11009 O OD1 . ASP D 1 83  ? -39.679 -17.884 7.229   1.00 45.35  ? 83  ASP D OD1 1 
ATOM   11010 O OD2 . ASP D 1 83  ? -38.124 -18.373 8.739   1.00 32.45  ? 83  ASP D OD2 1 
ATOM   11011 N N   . ARG D 1 84  ? -42.869 -17.713 11.379  1.00 42.51  ? 84  ARG D N   1 
ATOM   11012 C CA  . ARG D 1 84  ? -43.985 -18.234 12.176  1.00 46.71  ? 84  ARG D CA  1 
ATOM   11013 C C   . ARG D 1 84  ? -45.281 -17.497 11.814  1.00 46.71  ? 84  ARG D C   1 
ATOM   11014 O O   . ARG D 1 84  ? -46.345 -18.104 11.775  1.00 47.00  ? 84  ARG D O   1 
ATOM   11015 C CB  . ARG D 1 84  ? -43.743 -18.136 13.683  1.00 46.03  ? 84  ARG D CB  1 
ATOM   11016 C CG  . ARG D 1 84  ? -42.989 -19.317 14.274  1.00 58.60  ? 84  ARG D CG  1 
ATOM   11017 C CD  . ARG D 1 84  ? -43.081 -19.371 15.810  1.00 63.25  ? 84  ARG D CD  1 
ATOM   11018 N NE  . ARG D 1 84  ? -42.505 -18.168 16.431  1.00 79.05  ? 84  ARG D NE  1 
ATOM   11019 C CZ  . ARG D 1 84  ? -43.211 -17.155 17.003  1.00 87.62  ? 84  ARG D CZ  1 
ATOM   11020 N NH1 . ARG D 1 84  ? -44.532 -17.236 17.152  1.00 83.23  ? 84  ARG D NH1 1 
ATOM   11021 N NH2 . ARG D 1 84  ? -42.576 -16.081 17.435  1.00 88.83  ? 84  ARG D NH2 1 
ATOM   11022 N N   . ARG D 1 85  ? -45.180 -16.187 11.556  1.00 39.64  ? 85  ARG D N   1 
ATOM   11023 C CA  . ARG D 1 85  ? -46.362 -15.366 11.311  1.00 38.73  ? 85  ARG D CA  1 
ATOM   11024 C C   . ARG D 1 85  ? -46.485 -15.027 9.829   1.00 35.65  ? 85  ARG D C   1 
ATOM   11025 O O   . ARG D 1 85  ? -47.037 -13.986 9.485   1.00 33.77  ? 85  ARG D O   1 
ATOM   11026 C CB  . ARG D 1 85  ? -46.306 -14.084 12.127  1.00 34.03  ? 85  ARG D CB  1 
ATOM   11027 C CG  . ARG D 1 85  ? -46.128 -14.354 13.611  1.00 34.34  ? 85  ARG D CG  1 
ATOM   11028 C CD  . ARG D 1 85  ? -46.353 -13.109 14.453  1.00 33.81  ? 85  ARG D CD  1 
ATOM   11029 N NE  . ARG D 1 85  ? -46.227 -13.411 15.876  1.00 36.71  ? 85  ARG D NE  1 
ATOM   11030 C CZ  . ARG D 1 85  ? -47.232 -13.643 16.698  1.00 40.31  ? 85  ARG D CZ  1 
ATOM   11031 N NH1 . ARG D 1 85  ? -48.468 -13.670 16.242  1.00 42.46  ? 85  ARG D NH1 1 
ATOM   11032 N NH2 . ARG D 1 85  ? -47.001 -13.852 17.982  1.00 46.11  ? 85  ARG D NH2 1 
ATOM   11033 N N   . HIS D 1 86  ? -46.003 -15.945 8.971   1.00 33.32  ? 86  HIS D N   1 
ATOM   11034 C CA  . HIS D 1 86  ? -45.976 -15.755 7.522   1.00 34.27  ? 86  HIS D CA  1 
ATOM   11035 C C   . HIS D 1 86  ? -47.358 -15.322 7.010   1.00 34.74  ? 86  HIS D C   1 
ATOM   11036 O O   . HIS D 1 86  ? -47.500 -14.246 6.460   1.00 32.60  ? 86  HIS D O   1 
ATOM   11037 C CB  . HIS D 1 86  ? -45.493 -17.046 6.844   1.00 34.04  ? 86  HIS D CB  1 
ATOM   11038 C CG  . HIS D 1 86  ? -45.281 -16.932 5.379   1.00 34.21  ? 86  HIS D CG  1 
ATOM   11039 N ND1 . HIS D 1 86  ? -44.488 -17.817 4.689   1.00 37.37  ? 86  HIS D ND1 1 
ATOM   11040 C CD2 . HIS D 1 86  ? -45.777 -16.093 4.467   1.00 35.05  ? 86  HIS D CD2 1 
ATOM   11041 C CE1 . HIS D 1 86  ? -44.517 -17.515 3.392   1.00 37.77  ? 86  HIS D CE1 1 
ATOM   11042 N NE2 . HIS D 1 86  ? -45.288 -16.469 3.238   1.00 36.31  ? 86  HIS D NE2 1 
ATOM   11043 N N   . GLU D 1 87  ? -48.378 -16.175 7.235   1.00 39.90  ? 87  GLU D N   1 
ATOM   11044 C CA  . GLU D 1 87  ? -49.724 -15.954 6.699   1.00 38.53  ? 87  GLU D CA  1 
ATOM   11045 C C   . GLU D 1 87  ? -50.355 -14.719 7.340   1.00 34.72  ? 87  GLU D C   1 
ATOM   11046 O O   . GLU D 1 87  ? -50.947 -13.919 6.646   1.00 42.31  ? 87  GLU D O   1 
ATOM   11047 C CB  . GLU D 1 87  ? -50.615 -17.187 6.874   1.00 36.79  ? 87  GLU D CB  1 
ATOM   11048 C CG  . GLU D 1 87  ? -52.023 -17.015 6.294   1.00 39.88  ? 87  GLU D CG  1 
ATOM   11049 C CD  . GLU D 1 87  ? -52.071 -16.349 4.912   1.00 42.88  ? 87  GLU D CD  1 
ATOM   11050 O OE1 . GLU D 1 87  ? -51.239 -16.700 4.004   1.00 35.07  ? 87  GLU D OE1 1 
ATOM   11051 O OE2 . GLU D 1 87  ? -52.924 -15.469 4.754   1.00 43.00  ? 87  GLU D OE2 1 
ATOM   11052 N N   . GLU D 1 88  ? -50.160 -14.547 8.649   1.00 32.44  ? 88  GLU D N   1 
ATOM   11053 C CA  . GLU D 1 88  ? -50.633 -13.348 9.357   1.00 34.17  ? 88  GLU D CA  1 
ATOM   11054 C C   . GLU D 1 88  ? -50.064 -12.057 8.714   1.00 33.83  ? 88  GLU D C   1 
ATOM   11055 O O   . GLU D 1 88  ? -50.797 -11.085 8.522   1.00 33.96  ? 88  GLU D O   1 
ATOM   11056 C CB  . GLU D 1 88  ? -50.262 -13.427 10.840  1.00 36.93  ? 88  GLU D CB  1 
ATOM   11057 C CG  . GLU D 1 88  ? -50.595 -12.158 11.633  1.00 38.07  ? 88  GLU D CG  1 
ATOM   11058 C CD  . GLU D 1 88  ? -50.346 -12.281 13.134  1.00 40.04  ? 88  GLU D CD  1 
ATOM   11059 O OE1 . GLU D 1 88  ? -49.750 -13.319 13.544  1.00 35.47  ? 88  GLU D OE1 1 
ATOM   11060 O OE2 . GLU D 1 88  ? -50.761 -11.352 13.911  1.00 41.12  ? 88  GLU D OE2 1 
ATOM   11061 N N   . ILE D 1 89  ? -48.756 -12.047 8.392   1.00 33.13  ? 89  ILE D N   1 
ATOM   11062 C CA  . ILE D 1 89  ? -48.131 -10.861 7.789   1.00 31.57  ? 89  ILE D CA  1 
ATOM   11063 C C   . ILE D 1 89  ? -48.721 -10.634 6.395   1.00 28.79  ? 89  ILE D C   1 
ATOM   11064 O O   . ILE D 1 89  ? -49.109 -9.515  6.064   1.00 27.80  ? 89  ILE D O   1 
ATOM   11065 C CB  . ILE D 1 89  ? -46.590 -10.977 7.754   1.00 29.97  ? 89  ILE D CB  1 
ATOM   11066 C CG1 . ILE D 1 89  ? -45.998 -10.884 9.128   1.00 28.57  ? 89  ILE D CG1 1 
ATOM   11067 C CG2 . ILE D 1 89  ? -45.962 -9.932  6.812   1.00 30.65  ? 89  ILE D CG2 1 
ATOM   11068 C CD1 . ILE D 1 89  ? -44.673 -11.615 9.265   1.00 29.24  ? 89  ILE D CD1 1 
ATOM   11069 N N   . VAL D 1 90  ? -48.769 -11.693 5.585   1.00 25.40  ? 90  VAL D N   1 
ATOM   11070 C CA  . VAL D 1 90  ? -49.269 -11.586 4.225   1.00 28.78  ? 90  VAL D CA  1 
ATOM   11071 C C   . VAL D 1 90  ? -50.744 -11.124 4.254   1.00 33.83  ? 90  VAL D C   1 
ATOM   11072 O O   . VAL D 1 90  ? -51.163 -10.302 3.441   1.00 33.79  ? 90  VAL D O   1 
ATOM   11073 C CB  . VAL D 1 90  ? -49.105 -12.920 3.462   1.00 32.48  ? 90  VAL D CB  1 
ATOM   11074 C CG1 . VAL D 1 90  ? -49.956 -12.961 2.203   1.00 32.78  ? 90  VAL D CG1 1 
ATOM   11075 C CG2 . VAL D 1 90  ? -47.630 -13.224 3.117   1.00 32.13  ? 90  VAL D CG2 1 
ATOM   11076 N N   . ASP D 1 91  ? -51.528 -11.659 5.200   1.00 35.19  ? 91  ASP D N   1 
ATOM   11077 C CA  . ASP D 1 91  ? -52.948 -11.351 5.267   1.00 33.98  ? 91  ASP D CA  1 
ATOM   11078 C C   . ASP D 1 91  ? -53.137 -9.868  5.606   1.00 34.32  ? 91  ASP D C   1 
ATOM   11079 O O   . ASP D 1 91  ? -54.052 -9.225  5.102   1.00 35.92  ? 91  ASP D O   1 
ATOM   11080 C CB  . ASP D 1 91  ? -53.679 -12.265 6.235   1.00 35.61  ? 91  ASP D CB  1 
ATOM   11081 C CG  . ASP D 1 91  ? -55.194 -12.081 6.291   1.00 41.07  ? 91  ASP D CG  1 
ATOM   11082 O OD1 . ASP D 1 91  ? -55.856 -12.287 5.248   1.00 41.64  ? 91  ASP D OD1 1 
ATOM   11083 O OD2 . ASP D 1 91  ? -55.699 -11.698 7.363   1.00 50.26  ? 91  ASP D OD2 1 
ATOM   11084 N N   . TRP D 1 92  ? -52.273 -9.325  6.451   1.00 29.60  ? 92  TRP D N   1 
ATOM   11085 C CA  . TRP D 1 92  ? -52.385 -7.920  6.809   1.00 30.53  ? 92  TRP D CA  1 
ATOM   11086 C C   . TRP D 1 92  ? -52.087 -7.026  5.595   1.00 30.82  ? 92  TRP D C   1 
ATOM   11087 O O   . TRP D 1 92  ? -52.774 -6.046  5.372   1.00 29.91  ? 92  TRP D O   1 
ATOM   11088 C CB  . TRP D 1 92  ? -51.471 -7.586  7.968   1.00 30.04  ? 92  TRP D CB  1 
ATOM   11089 C CG  . TRP D 1 92  ? -52.191 -7.512  9.272   1.00 33.14  ? 92  TRP D CG  1 
ATOM   11090 C CD1 . TRP D 1 92  ? -52.059 -8.357  10.344  1.00 33.59  ? 92  TRP D CD1 1 
ATOM   11091 C CD2 . TRP D 1 92  ? -53.182 -6.549  9.636   1.00 33.83  ? 92  TRP D CD2 1 
ATOM   11092 N NE1 . TRP D 1 92  ? -52.882 -7.968  11.352  1.00 34.81  ? 92  TRP D NE1 1 
ATOM   11093 C CE2 . TRP D 1 92  ? -53.597 -6.866  10.948  1.00 35.44  ? 92  TRP D CE2 1 
ATOM   11094 C CE3 . TRP D 1 92  ? -53.762 -5.458  8.987   1.00 38.27  ? 92  TRP D CE3 1 
ATOM   11095 C CZ2 . TRP D 1 92  ? -54.569 -6.128  11.617  1.00 33.75  ? 92  TRP D CZ2 1 
ATOM   11096 C CZ3 . TRP D 1 92  ? -54.742 -4.738  9.644   1.00 36.24  ? 92  TRP D CZ3 1 
ATOM   11097 C CH2 . TRP D 1 92  ? -55.136 -5.071  10.940  1.00 34.27  ? 92  TRP D CH2 1 
ATOM   11098 N N   . ILE D 1 93  ? -51.089 -7.400  4.797   1.00 30.04  ? 93  ILE D N   1 
ATOM   11099 C CA  . ILE D 1 93  ? -50.697 -6.599  3.645   1.00 27.66  ? 93  ILE D CA  1 
ATOM   11100 C C   . ILE D 1 93  ? -51.852 -6.545  2.634   1.00 29.74  ? 93  ILE D C   1 
ATOM   11101 O O   . ILE D 1 93  ? -52.156 -5.458  2.105   1.00 29.45  ? 93  ILE D O   1 
ATOM   11102 C CB  . ILE D 1 93  ? -49.408 -7.136  3.024   1.00 27.76  ? 93  ILE D CB  1 
ATOM   11103 C CG1 . ILE D 1 93  ? -48.232 -7.024  3.993   1.00 28.37  ? 93  ILE D CG1 1 
ATOM   11104 C CG2 . ILE D 1 93  ? -49.098 -6.443  1.700   1.00 27.24  ? 93  ILE D CG2 1 
ATOM   11105 C CD1 . ILE D 1 93  ? -47.011 -7.800  3.554   1.00 31.33  ? 93  ILE D CD1 1 
ATOM   11106 N N   . ILE D 1 94  ? -52.528 -7.704  2.399   1.00 27.77  ? 94  ILE D N   1 
ATOM   11107 C CA  . ILE D 1 94  ? -53.626 -7.766  1.434   1.00 28.11  ? 94  ILE D CA  1 
ATOM   11108 C C   . ILE D 1 94  ? -54.785 -6.865  1.902   1.00 31.19  ? 94  ILE D C   1 
ATOM   11109 O O   . ILE D 1 94  ? -55.285 -6.018  1.131   1.00 33.72  ? 94  ILE D O   1 
ATOM   11110 C CB  . ILE D 1 94  ? -54.100 -9.212  1.205   1.00 29.61  ? 94  ILE D CB  1 
ATOM   11111 C CG1 . ILE D 1 94  ? -53.045 -10.065 0.505   1.00 32.77  ? 94  ILE D CG1 1 
ATOM   11112 C CG2 . ILE D 1 94  ? -55.419 -9.226  0.437   1.00 32.30  ? 94  ILE D CG2 1 
ATOM   11113 C CD1 . ILE D 1 94  ? -53.193 -11.569 0.753   1.00 33.70  ? 94  ILE D CD1 1 
ATOM   11114 N N   . ARG D 1 95  ? -55.226 -7.056  3.151   1.00 32.02  ? 95  ARG D N   1 
ATOM   11115 C CA  . ARG D 1 95  ? -56.449 -6.427  3.634   1.00 33.50  ? 95  ARG D CA  1 
ATOM   11116 C C   . ARG D 1 95  ? -56.259 -4.907  3.750   1.00 34.83  ? 95  ARG D C   1 
ATOM   11117 O O   . ARG D 1 95  ? -57.094 -4.150  3.303   1.00 35.74  ? 95  ARG D O   1 
ATOM   11118 C CB  . ARG D 1 95  ? -56.877 -7.037  4.962   1.00 37.01  ? 95  ARG D CB  1 
ATOM   11119 C CG  . ARG D 1 95  ? -57.198 -8.521  4.875   1.00 40.17  ? 95  ARG D CG  1 
ATOM   11120 C CD  . ARG D 1 95  ? -57.884 -9.065  6.125   1.00 45.13  ? 95  ARG D CD  1 
ATOM   11121 N NE  . ARG D 1 95  ? -56.943 -9.166  7.253   1.00 62.40  ? 95  ARG D NE  1 
ATOM   11122 C CZ  . ARG D 1 95  ? -57.138 -8.770  8.536   1.00 65.54  ? 95  ARG D CZ  1 
ATOM   11123 N NH1 . ARG D 1 95  ? -58.251 -8.128  8.908   1.00 61.55  ? 95  ARG D NH1 1 
ATOM   11124 N NH2 . ARG D 1 95  ? -56.199 -9.027  9.436   1.00 66.30  ? 95  ARG D NH2 1 
ATOM   11125 N N   . GLU D 1 96  ? -55.149 -4.475  4.340   1.00 33.94  ? 96  GLU D N   1 
ATOM   11126 C CA  . GLU D 1 96  ? -54.940 -3.058  4.622   1.00 36.46  ? 96  GLU D CA  1 
ATOM   11127 C C   . GLU D 1 96  ? -54.528 -2.296  3.346   1.00 35.64  ? 96  GLU D C   1 
ATOM   11128 O O   . GLU D 1 96  ? -55.088 -1.262  3.044   1.00 34.35  ? 96  GLU D O   1 
ATOM   11129 C CB  . GLU D 1 96  ? -53.902 -2.876  5.718   1.00 38.47  ? 96  GLU D CB  1 
ATOM   11130 C CG  . GLU D 1 96  ? -53.699 -1.420  6.095   1.00 45.72  ? 96  GLU D CG  1 
ATOM   11131 C CD  . GLU D 1 96  ? -52.674 -1.206  7.191   1.00 51.74  ? 96  GLU D CD  1 
ATOM   11132 O OE1 . GLU D 1 96  ? -53.034 -0.583  8.206   1.00 51.99  ? 96  GLU D OE1 1 
ATOM   11133 O OE2 . GLU D 1 96  ? -51.516 -1.682  7.037   1.00 57.51  ? 96  GLU D OE2 1 
ATOM   11134 N N   . SER D 1 97  ? -53.518 -2.794  2.625   1.00 37.25  ? 97  SER D N   1 
ATOM   11135 C CA  . SER D 1 97  ? -52.931 -2.033  1.494   1.00 35.45  ? 97  SER D CA  1 
ATOM   11136 C C   . SER D 1 97  ? -53.692 -2.299  0.178   1.00 34.48  ? 97  SER D C   1 
ATOM   11137 O O   . SER D 1 97  ? -53.550 -1.563  -0.772  1.00 33.30  ? 97  SER D O   1 
ATOM   11138 C CB  . SER D 1 97  ? -51.441 -2.339  1.331   1.00 34.49  ? 97  SER D CB  1 
ATOM   11139 O OG  . SER D 1 97  ? -51.235 -3.635  0.772   1.00 34.35  ? 97  SER D OG  1 
ATOM   11140 N N   . GLY D 1 98  ? -54.418 -3.414  0.105   1.00 36.77  ? 98  GLY D N   1 
ATOM   11141 C CA  . GLY D 1 98  ? -55.128 -3.782  -1.117  1.00 34.89  ? 98  GLY D CA  1 
ATOM   11142 C C   . GLY D 1 98  ? -54.266 -4.567  -2.116  1.00 32.10  ? 98  GLY D C   1 
ATOM   11143 O O   . GLY D 1 98  ? -54.735 -4.944  -3.182  1.00 39.80  ? 98  GLY D O   1 
ATOM   11144 N N   . SER D 1 99  ? -53.032 -4.838  -1.757  1.00 32.77  ? 99  SER D N   1 
ATOM   11145 C CA  . SER D 1 99  ? -52.126 -5.598  -2.600  1.00 32.61  ? 99  SER D CA  1 
ATOM   11146 C C   . SER D 1 99  ? -52.658 -7.037  -2.846  1.00 32.33  ? 99  SER D C   1 
ATOM   11147 O O   . SER D 1 99  ? -53.177 -7.695  -1.929  1.00 29.33  ? 99  SER D O   1 
ATOM   11148 C CB  . SER D 1 99  ? -50.725 -5.610  -1.970  1.00 36.06  ? 99  SER D CB  1 
ATOM   11149 O OG  . SER D 1 99  ? -50.021 -6.802  -2.276  1.00 41.96  ? 99  SER D OG  1 
ATOM   11150 N N   . THR D 1 100 ? -52.384 -7.562  -4.043  1.00 32.07  ? 100 THR D N   1 
ATOM   11151 C CA  . THR D 1 100 ? -52.750 -8.962  -4.351  1.00 30.82  ? 100 THR D CA  1 
ATOM   11152 C C   . THR D 1 100 ? -51.901 -9.899  -3.516  1.00 29.79  ? 100 THR D C   1 
ATOM   11153 O O   . THR D 1 100 ? -50.816 -9.480  -3.070  1.00 28.20  ? 100 THR D O   1 
ATOM   11154 C CB  . THR D 1 100 ? -52.543 -9.214  -5.842  1.00 28.45  ? 100 THR D CB  1 
ATOM   11155 O OG1 . THR D 1 100 ? -51.135 -9.149  -6.039  1.00 30.06  ? 100 THR D OG1 1 
ATOM   11156 C CG2 . THR D 1 100 ? -53.246 -8.187  -6.710  1.00 29.60  ? 100 THR D CG2 1 
ATOM   11157 N N   . ARG D 1 101 ? -52.368 -11.158 -3.332  1.00 29.72  ? 101 ARG D N   1 
ATOM   11158 C CA  . ARG D 1 101 ? -51.627 -12.148 -2.517  1.00 34.05  ? 101 ARG D CA  1 
ATOM   11159 C C   . ARG D 1 101 ? -50.258 -12.412 -3.143  1.00 34.20  ? 101 ARG D C   1 
ATOM   11160 O O   . ARG D 1 101 ? -49.268 -12.516 -2.400  1.00 32.97  ? 101 ARG D O   1 
ATOM   11161 C CB  . ARG D 1 101 ? -52.418 -13.452 -2.391  1.00 50.00  ? 101 ARG D CB  1 
ATOM   11162 C CG  . ARG D 1 101 ? -52.785 -13.818 -0.962  1.00 50.00  ? 101 ARG D CG  1 
ATOM   11163 C CD  . ARG D 1 101 ? -52.863 -15.315 -0.705  1.00 50.00  ? 101 ARG D CD  1 
ATOM   11164 N NE  . ARG D 1 101 ? -53.286 -15.615 0.660   1.00 50.00  ? 101 ARG D NE  1 
ATOM   11165 C CZ  . ARG D 1 101 ? -53.544 -16.835 1.108   1.00 50.00  ? 101 ARG D CZ  1 
ATOM   11166 N NH1 . ARG D 1 101 ? -53.420 -17.881 0.301   1.00 50.00  ? 101 ARG D NH1 1 
ATOM   11167 N NH2 . ARG D 1 101 ? -53.924 -17.015 2.366   1.00 50.00  ? 101 ARG D NH2 1 
ATOM   11168 N N   . LEU D 1 102 ? -50.193 -12.493 -4.489  1.00 35.49  ? 102 LEU D N   1 
ATOM   11169 C CA  . LEU D 1 102 ? -48.914 -12.728 -5.201  1.00 40.41  ? 102 LEU D CA  1 
ATOM   11170 C C   . LEU D 1 102 ? -47.919 -11.628 -4.818  1.00 40.40  ? 102 LEU D C   1 
ATOM   11171 O O   . LEU D 1 102 ? -46.772 -11.960 -4.464  1.00 34.70  ? 102 LEU D O   1 
ATOM   11172 C CB  . LEU D 1 102 ? -49.178 -12.751 -6.704  1.00 43.58  ? 102 LEU D CB  1 
ATOM   11173 C CG  . LEU D 1 102 ? -48.029 -12.282 -7.601  1.00 53.77  ? 102 LEU D CG  1 
ATOM   11174 C CD1 . LEU D 1 102 ? -47.291 -13.464 -8.200  1.00 58.20  ? 102 LEU D CD1 1 
ATOM   11175 C CD2 . LEU D 1 102 ? -48.528 -11.352 -8.691  1.00 53.66  ? 102 LEU D CD2 1 
ATOM   11176 N N   . LYS D 1 103 ? -48.354 -10.369 -4.872  1.00 39.11  ? 103 LYS D N   1 
ATOM   11177 C CA  . LYS D 1 103 ? -47.425 -9.303  -4.599  1.00 42.41  ? 103 LYS D CA  1 
ATOM   11178 C C   . LYS D 1 103 ? -47.157 -9.183  -3.075  1.00 36.57  ? 103 LYS D C   1 
ATOM   11179 O O   . LYS D 1 103 ? -46.061 -8.835  -2.677  1.00 33.03  ? 103 LYS D O   1 
ATOM   11180 C CB  . LYS D 1 103 ? -47.919 -8.028  -5.256  1.00 50.54  ? 103 LYS D CB  1 
ATOM   11181 C CG  . LYS D 1 103 ? -46.893 -7.000  -5.361  1.00 71.28  ? 103 LYS D CG  1 
ATOM   11182 C CD  . LYS D 1 103 ? -47.365 -5.741  -6.055  1.00 94.07  ? 103 LYS D CD  1 
ATOM   11183 C CE  . LYS D 1 103 ? -47.408 -4.540  -5.153  1.00 108.80 ? 103 LYS D CE  1 
ATOM   11184 N NZ  . LYS D 1 103 ? -47.335 -3.323  -5.973  1.00 119.93 ? 103 LYS D NZ  1 
ATOM   11185 N N   . ALA D 1 104 ? -48.139 -9.544  -2.232  1.00 36.11  ? 104 ALA D N   1 
ATOM   11186 C CA  . ALA D 1 104 ? -47.924 -9.592  -0.781  1.00 34.06  ? 104 ALA D CA  1 
ATOM   11187 C C   . ALA D 1 104 ? -46.860 -10.640 -0.411  1.00 32.87  ? 104 ALA D C   1 
ATOM   11188 O O   . ALA D 1 104 ? -46.088 -10.413 0.511   1.00 32.85  ? 104 ALA D O   1 
ATOM   11189 C CB  . ALA D 1 104 ? -49.230 -9.861  -0.058  1.00 32.28  ? 104 ALA D CB  1 
ATOM   11190 N N   . GLU D 1 105 ? -46.867 -11.810 -1.102  1.00 33.26  ? 105 GLU D N   1 
ATOM   11191 C CA  . GLU D 1 105 ? -45.894 -12.886 -0.822  1.00 34.31  ? 105 GLU D CA  1 
ATOM   11192 C C   . GLU D 1 105 ? -44.481 -12.407 -1.190  1.00 32.74  ? 105 GLU D C   1 
ATOM   11193 O O   . GLU D 1 105 ? -43.522 -12.700 -0.489  1.00 34.94  ? 105 GLU D O   1 
ATOM   11194 C CB  . GLU D 1 105 ? -46.189 -14.201 -1.575  1.00 30.39  ? 105 GLU D CB  1 
ATOM   11195 C CG  . GLU D 1 105 ? -47.333 -15.010 -0.979  1.00 33.76  ? 105 GLU D CG  1 
ATOM   11196 C CD  . GLU D 1 105 ? -47.013 -15.710 0.341   1.00 40.63  ? 105 GLU D CD  1 
ATOM   11197 O OE1 . GLU D 1 105 ? -45.805 -15.726 0.751   1.00 37.22  ? 105 GLU D OE1 1 
ATOM   11198 O OE2 . GLU D 1 105 ? -47.984 -16.219 0.985   1.00 43.31  ? 105 GLU D OE2 1 
ATOM   11199 N N   . ILE D 1 106 ? -44.370 -11.699 -2.312  1.00 30.35  ? 106 ILE D N   1 
ATOM   11200 C CA  . ILE D 1 106 ? -43.108 -11.147 -2.754  1.00 29.43  ? 106 ILE D CA  1 
ATOM   11201 C C   . ILE D 1 106 ? -42.628 -10.135 -1.734  1.00 31.77  ? 106 ILE D C   1 
ATOM   11202 O O   . ILE D 1 106 ? -41.464 -10.146 -1.362  1.00 35.29  ? 106 ILE D O   1 
ATOM   11203 C CB  . ILE D 1 106 ? -43.259 -10.549 -4.155  1.00 30.60  ? 106 ILE D CB  1 
ATOM   11204 C CG1 . ILE D 1 106 ? -43.233 -11.626 -5.175  1.00 30.80  ? 106 ILE D CG1 1 
ATOM   11205 C CG2 . ILE D 1 106 ? -42.203 -9.470  -4.459  1.00 28.74  ? 106 ILE D CG2 1 
ATOM   11206 C CD1 . ILE D 1 106 ? -43.750 -11.187 -6.529  1.00 35.97  ? 106 ILE D CD1 1 
ATOM   11207 N N   . GLU D 1 107 ? -43.552 -9.305  -1.232  1.00 33.52  ? 107 GLU D N   1 
ATOM   11208 C CA  . GLU D 1 107 ? -43.215 -8.284  -0.242  1.00 33.64  ? 107 GLU D CA  1 
ATOM   11209 C C   . GLU D 1 107 ? -42.763 -8.946  1.070   1.00 31.58  ? 107 GLU D C   1 
ATOM   11210 O O   . GLU D 1 107 ? -41.793 -8.502  1.683   1.00 31.86  ? 107 GLU D O   1 
ATOM   11211 C CB  . GLU D 1 107 ? -44.372 -7.317  -0.063  1.00 33.89  ? 107 GLU D CB  1 
ATOM   11212 C CG  . GLU D 1 107 ? -44.107 -6.290  1.009   1.00 41.63  ? 107 GLU D CG  1 
ATOM   11213 C CD  . GLU D 1 107 ? -44.953 -5.036  0.942   1.00 46.53  ? 107 GLU D CD  1 
ATOM   11214 O OE1 . GLU D 1 107 ? -46.039 -5.032  0.290   1.00 54.88  ? 107 GLU D OE1 1 
ATOM   11215 O OE2 . GLU D 1 107 ? -44.508 -4.054  1.543   1.00 49.30  ? 107 GLU D OE2 1 
ATOM   11216 N N   . TRP D 1 108 ? -43.404 -10.050 1.449   1.00 28.47  ? 108 TRP D N   1 
ATOM   11217 C CA  . TRP D 1 108 ? -42.973 -10.801 2.636   1.00 29.46  ? 108 TRP D CA  1 
ATOM   11218 C C   . TRP D 1 108 ? -41.527 -11.290 2.486   1.00 29.15  ? 108 TRP D C   1 
ATOM   11219 O O   . TRP D 1 108 ? -40.723 -11.148 3.405   1.00 24.81  ? 108 TRP D O   1 
ATOM   11220 C CB  . TRP D 1 108 ? -43.901 -11.969 2.911   1.00 28.76  ? 108 TRP D CB  1 
ATOM   11221 C CG  . TRP D 1 108 ? -43.435 -12.848 4.031   1.00 30.97  ? 108 TRP D CG  1 
ATOM   11222 C CD1 . TRP D 1 108 ? -43.673 -12.689 5.364   1.00 35.22  ? 108 TRP D CD1 1 
ATOM   11223 C CD2 . TRP D 1 108 ? -42.618 -14.029 3.909   1.00 35.12  ? 108 TRP D CD2 1 
ATOM   11224 N NE1 . TRP D 1 108 ? -43.075 -13.705 6.090   1.00 32.66  ? 108 TRP D NE1 1 
ATOM   11225 C CE2 . TRP D 1 108 ? -42.425 -14.541 5.225   1.00 34.73  ? 108 TRP D CE2 1 
ATOM   11226 C CE3 . TRP D 1 108 ? -42.014 -14.688 2.831   1.00 34.20  ? 108 TRP D CE3 1 
ATOM   11227 C CZ2 . TRP D 1 108 ? -41.667 -15.680 5.474   1.00 34.82  ? 108 TRP D CZ2 1 
ATOM   11228 C CZ3 . TRP D 1 108 ? -41.260 -15.817 3.085   1.00 34.85  ? 108 TRP D CZ3 1 
ATOM   11229 C CH2 . TRP D 1 108 ? -41.085 -16.300 4.391   1.00 33.71  ? 108 TRP D CH2 1 
ATOM   11230 N N   . GLY D 1 109 ? -41.223 -11.874 1.324   1.00 30.74  ? 109 GLY D N   1 
ATOM   11231 C CA  . GLY D 1 109 ? -39.925 -12.456 1.057   1.00 30.46  ? 109 GLY D CA  1 
ATOM   11232 C C   . GLY D 1 109 ? -38.832 -11.394 1.070   1.00 30.70  ? 109 GLY D C   1 
ATOM   11233 O O   . GLY D 1 109 ? -37.749 -11.604 1.640   1.00 29.69  ? 109 GLY D O   1 
ATOM   11234 N N   . ALA D 1 110 ? -39.126 -10.255 0.445   1.00 28.00  ? 110 ALA D N   1 
ATOM   11235 C CA  . ALA D 1 110 ? -38.184 -9.139  0.385   1.00 26.72  ? 110 ALA D CA  1 
ATOM   11236 C C   . ALA D 1 110 ? -37.830 -8.655  1.799   1.00 29.79  ? 110 ALA D C   1 
ATOM   11237 O O   . ALA D 1 110 ? -36.658 -8.518  2.128   1.00 27.16  ? 110 ALA D O   1 
ATOM   11238 C CB  . ALA D 1 110 ? -38.757 -8.025  -0.452  1.00 25.19  ? 110 ALA D CB  1 
ATOM   11239 N N   . ALA D 1 111 ? -38.855 -8.464  2.651   1.00 29.78  ? 111 ALA D N   1 
ATOM   11240 C CA  . ALA D 1 111 ? -38.643 -7.971  4.002   1.00 28.73  ? 111 ALA D CA  1 
ATOM   11241 C C   . ALA D 1 111 ? -37.829 -8.969  4.817   1.00 29.03  ? 111 ALA D C   1 
ATOM   11242 O O   . ALA D 1 111 ? -36.927 -8.576  5.546   1.00 30.13  ? 111 ALA D O   1 
ATOM   11243 C CB  . ALA D 1 111 ? -39.954 -7.682  4.656   1.00 29.53  ? 111 ALA D CB  1 
ATOM   11244 N N   . ARG D 1 112 ? -38.156 -10.261 4.690   1.00 33.03  ? 112 ARG D N   1 
ATOM   11245 C CA  . ARG D 1 112 ? -37.440 -11.311 5.424   1.00 32.76  ? 112 ARG D CA  1 
ATOM   11246 C C   . ARG D 1 112 ? -35.961 -11.303 5.031   1.00 32.79  ? 112 ARG D C   1 
ATOM   11247 O O   . ARG D 1 112 ? -35.084 -11.400 5.898   1.00 34.88  ? 112 ARG D O   1 
ATOM   11248 C CB  . ARG D 1 112 ? -38.027 -12.691 5.149   1.00 31.72  ? 112 ARG D CB  1 
ATOM   11249 C CG  . ARG D 1 112 ? -37.447 -13.822 5.993   1.00 31.23  ? 112 ARG D CG  1 
ATOM   11250 C CD  . ARG D 1 112 ? -37.636 -15.183 5.279   1.00 35.03  ? 112 ARG D CD  1 
ATOM   11251 N NE  . ARG D 1 112 ? -37.337 -16.329 6.150   1.00 32.85  ? 112 ARG D NE  1 
ATOM   11252 C CZ  . ARG D 1 112 ? -36.160 -16.942 6.191   1.00 31.60  ? 112 ARG D CZ  1 
ATOM   11253 N NH1 . ARG D 1 112 ? -35.137 -16.473 5.514   1.00 32.16  ? 112 ARG D NH1 1 
ATOM   11254 N NH2 . ARG D 1 112 ? -36.005 -18.013 6.922   1.00 35.21  ? 112 ARG D NH2 1 
ATOM   11255 N N   . ALA D 1 113 ? -35.696 -11.124 3.733   1.00 30.07  ? 113 ALA D N   1 
ATOM   11256 C CA  . ALA D 1 113 ? -34.344 -11.175 3.205   1.00 30.43  ? 113 ALA D CA  1 
ATOM   11257 C C   . ALA D 1 113 ? -33.519 -9.991  3.719   1.00 29.83  ? 113 ALA D C   1 
ATOM   11258 O O   . ALA D 1 113 ? -32.339 -10.149 4.030   1.00 24.93  ? 113 ALA D O   1 
ATOM   11259 C CB  . ALA D 1 113 ? -34.385 -11.210 1.681   1.00 29.53  ? 113 ALA D CB  1 
ATOM   11260 N N   . ILE D 1 114 ? -34.147 -8.809  3.786   1.00 30.05  ? 114 ILE D N   1 
ATOM   11261 C CA  . ILE D 1 114 ? -33.482 -7.630  4.303   1.00 34.05  ? 114 ILE D CA  1 
ATOM   11262 C C   . ILE D 1 114 ? -33.062 -7.913  5.746   1.00 32.67  ? 114 ILE D C   1 
ATOM   11263 O O   . ILE D 1 114 ? -31.952 -7.568  6.153   1.00 32.07  ? 114 ILE D O   1 
ATOM   11264 C CB  . ILE D 1 114 ? -34.388 -6.391  4.223   1.00 39.29  ? 114 ILE D CB  1 
ATOM   11265 C CG1 . ILE D 1 114 ? -34.980 -6.201  2.835   1.00 46.12  ? 114 ILE D CG1 1 
ATOM   11266 C CG2 . ILE D 1 114 ? -33.649 -5.136  4.711   1.00 40.34  ? 114 ILE D CG2 1 
ATOM   11267 C CD1 . ILE D 1 114 ? -34.088 -5.479  1.857   1.00 50.40  ? 114 ILE D CD1 1 
ATOM   11268 N N   . THR D 1 115 ? -33.979 -8.529  6.510   1.00 32.00  ? 115 THR D N   1 
ATOM   11269 C CA  . THR D 1 115 ? -33.777 -8.777  7.928   1.00 32.59  ? 115 THR D CA  1 
ATOM   11270 C C   . THR D 1 115 ? -32.604 -9.750  8.119   1.00 34.61  ? 115 THR D C   1 
ATOM   11271 O O   . THR D 1 115 ? -31.790 -9.548  8.999   1.00 34.95  ? 115 THR D O   1 
ATOM   11272 C CB  . THR D 1 115 ? -35.072 -9.310  8.561   1.00 32.46  ? 115 THR D CB  1 
ATOM   11273 O OG1 . THR D 1 115 ? -36.088 -8.386  8.176   1.00 31.23  ? 115 THR D OG1 1 
ATOM   11274 C CG2 . THR D 1 115 ? -34.982 -9.440  10.082  1.00 31.05  ? 115 THR D CG2 1 
ATOM   11275 N N   . LEU D 1 116 ? -32.552 -10.812 7.304   1.00 33.68  ? 116 LEU D N   1 
ATOM   11276 C CA  . LEU D 1 116 ? -31.506 -11.814 7.421   1.00 34.10  ? 116 LEU D CA  1 
ATOM   11277 C C   . LEU D 1 116 ? -30.142 -11.186 7.064   1.00 34.88  ? 116 LEU D C   1 
ATOM   11278 O O   . LEU D 1 116 ? -29.142 -11.399 7.775   1.00 34.41  ? 116 LEU D O   1 
ATOM   11279 C CB  . LEU D 1 116 ? -31.813 -13.025 6.539   1.00 34.24  ? 116 LEU D CB  1 
ATOM   11280 C CG  . LEU D 1 116 ? -30.804 -14.177 6.621   1.00 38.48  ? 116 LEU D CG  1 
ATOM   11281 C CD1 . LEU D 1 116 ? -30.572 -14.578 8.087   1.00 37.79  ? 116 LEU D CD1 1 
ATOM   11282 C CD2 . LEU D 1 116 ? -31.242 -15.380 5.796   1.00 40.79  ? 116 LEU D CD2 1 
ATOM   11283 N N   . GLU D 1 117 ? -30.130 -10.378 6.007   1.00 33.94  ? 117 GLU D N   1 
ATOM   11284 C CA  . GLU D 1 117 ? -28.939 -9.661  5.574   1.00 38.56  ? 117 GLU D CA  1 
ATOM   11285 C C   . GLU D 1 117 ? -28.418 -8.733  6.693   1.00 37.97  ? 117 GLU D C   1 
ATOM   11286 O O   . GLU D 1 117 ? -27.208 -8.671  6.927   1.00 42.07  ? 117 GLU D O   1 
ATOM   11287 C CB  . GLU D 1 117 ? -29.251 -8.866  4.303   1.00 46.80  ? 117 GLU D CB  1 
ATOM   11288 C CG  . GLU D 1 117 ? -28.031 -8.154  3.709   1.00 62.95  ? 117 GLU D CG  1 
ATOM   11289 C CD  . GLU D 1 117 ? -27.029 -9.051  2.989   1.00 71.86  ? 117 GLU D CD  1 
ATOM   11290 O OE1 . GLU D 1 117 ? -27.339 -10.253 2.804   1.00 81.59  ? 117 GLU D OE1 1 
ATOM   11291 O OE2 . GLU D 1 117 ? -25.952 -8.537  2.577   1.00 75.73  ? 117 GLU D OE2 1 
ATOM   11292 N N   . SER D 1 118 ? -29.330 -7.996  7.356   1.00 33.90  ? 118 SER D N   1 
ATOM   11293 C CA  . SER D 1 118 ? -28.939 -6.959  8.313   1.00 34.06  ? 118 SER D CA  1 
ATOM   11294 C C   . SER D 1 118 ? -28.223 -7.580  9.506   1.00 33.16  ? 118 SER D C   1 
ATOM   11295 O O   . SER D 1 118 ? -27.428 -6.928  10.149  1.00 31.57  ? 118 SER D O   1 
ATOM   11296 C CB  . SER D 1 118 ? -30.151 -6.142  8.777   1.00 34.13  ? 118 SER D CB  1 
ATOM   11297 O OG  . SER D 1 118 ? -30.690 -5.349  7.716   1.00 30.95  ? 118 SER D OG  1 
ATOM   11298 N N   . ALA D 1 119 ? -28.536 -8.847  9.804   1.00 33.19  ? 119 ALA D N   1 
ATOM   11299 C CA  . ALA D 1 119 ? -28.001 -9.505  10.984  1.00 35.50  ? 119 ALA D CA  1 
ATOM   11300 C C   . ALA D 1 119 ? -26.482 -9.628  10.895  1.00 33.02  ? 119 ALA D C   1 
ATOM   11301 O O   . ALA D 1 119 ? -25.826 -9.796  11.912  1.00 37.78  ? 119 ALA D O   1 
ATOM   11302 C CB  . ALA D 1 119 ? -28.651 -10.870 11.160  1.00 39.23  ? 119 ALA D CB  1 
ATOM   11303 N N   . SER D 1 120 ? -25.941 -9.596  9.671   1.00 34.17  ? 120 SER D N   1 
ATOM   11304 C CA  . SER D 1 120 ? -24.506 -9.770  9.451   1.00 38.09  ? 120 SER D CA  1 
ATOM   11305 C C   . SER D 1 120 ? -23.783 -8.420  9.499   1.00 39.97  ? 120 SER D C   1 
ATOM   11306 O O   . SER D 1 120 ? -22.555 -8.390  9.548   1.00 47.97  ? 120 SER D O   1 
ATOM   11307 C CB  . SER D 1 120 ? -24.218 -10.488 8.121   1.00 39.11  ? 120 SER D CB  1 
ATOM   11308 O OG  . SER D 1 120 ? -24.335 -9.593  7.014   1.00 40.44  ? 120 SER D OG  1 
ATOM   11309 N N   . PHE D 1 121 ? -24.543 -7.305  9.504   1.00 38.92  ? 121 PHE D N   1 
ATOM   11310 C CA  . PHE D 1 121 ? -23.951 -5.974  9.337   1.00 38.95  ? 121 PHE D CA  1 
ATOM   11311 C C   . PHE D 1 121 ? -23.055 -5.602  10.525  1.00 38.11  ? 121 PHE D C   1 
ATOM   11312 O O   . PHE D 1 121 ? -21.974 -5.089  10.319  1.00 45.47  ? 121 PHE D O   1 
ATOM   11313 C CB  . PHE D 1 121 ? -25.012 -4.913  9.104   1.00 41.10  ? 121 PHE D CB  1 
ATOM   11314 C CG  . PHE D 1 121 ? -25.614 -4.951  7.705   1.00 43.62  ? 121 PHE D CG  1 
ATOM   11315 C CD1 . PHE D 1 121 ? -26.713 -4.153  7.382   1.00 46.73  ? 121 PHE D CD1 1 
ATOM   11316 C CD2 . PHE D 1 121 ? -25.106 -5.810  6.724   1.00 40.96  ? 121 PHE D CD2 1 
ATOM   11317 C CE1 . PHE D 1 121 ? -27.285 -4.210  6.120   1.00 47.39  ? 121 PHE D CE1 1 
ATOM   11318 C CE2 . PHE D 1 121 ? -25.669 -5.843  5.458   1.00 44.45  ? 121 PHE D CE2 1 
ATOM   11319 C CZ  . PHE D 1 121 ? -26.758 -5.042  5.158   1.00 44.46  ? 121 PHE D CZ  1 
ATOM   11320 N N   . PRO D 1 122 ? -23.460 -5.829  11.790  1.00 35.28  ? 122 PRO D N   1 
ATOM   11321 C CA  . PRO D 1 122 ? -22.610 -5.474  12.936  1.00 37.28  ? 122 PRO D CA  1 
ATOM   11322 C C   . PRO D 1 122 ? -21.168 -5.996  12.852  1.00 40.10  ? 122 PRO D C   1 
ATOM   11323 O O   . PRO D 1 122 ? -20.227 -5.319  13.230  1.00 38.04  ? 122 PRO D O   1 
ATOM   11324 C CB  . PRO D 1 122 ? -23.385 -6.115  14.102  1.00 38.17  ? 122 PRO D CB  1 
ATOM   11325 C CG  . PRO D 1 122 ? -24.845 -6.085  13.633  1.00 38.15  ? 122 PRO D CG  1 
ATOM   11326 C CD  . PRO D 1 122 ? -24.740 -6.428  12.187  1.00 37.74  ? 122 PRO D CD  1 
ATOM   11327 N N   . ALA D 1 123 ? -21.020 -7.204  12.339  1.00 42.95  ? 123 ALA D N   1 
ATOM   11328 C CA  . ALA D 1 123 ? -19.725 -7.838  12.222  1.00 43.19  ? 123 ALA D CA  1 
ATOM   11329 C C   . ALA D 1 123 ? -18.879 -7.142  11.158  1.00 38.77  ? 123 ALA D C   1 
ATOM   11330 O O   . ALA D 1 123 ? -17.682 -7.246  11.189  1.00 50.18  ? 123 ALA D O   1 
ATOM   11331 C CB  . ALA D 1 123 ? -19.900 -9.327  11.902  1.00 44.95  ? 123 ALA D CB  1 
ATOM   11332 N N   . ARG D 1 124 ? -19.523 -6.474  10.195  1.00 38.91  ? 124 ARG D N   1 
ATOM   11333 C CA  . ARG D 1 124 ? -18.821 -5.946  9.034   1.00 39.41  ? 124 ARG D CA  1 
ATOM   11334 C C   . ARG D 1 124 ? -18.411 -4.484  9.229   1.00 42.14  ? 124 ARG D C   1 
ATOM   11335 O O   . ARG D 1 124 ? -17.621 -3.981  8.452   1.00 48.00  ? 124 ARG D O   1 
ATOM   11336 C CB  . ARG D 1 124 ? -19.681 -6.052  7.783   1.00 42.53  ? 124 ARG D CB  1 
ATOM   11337 C CG  . ARG D 1 124 ? -19.762 -7.473  7.235   1.00 41.60  ? 124 ARG D CG  1 
ATOM   11338 C CD  . ARG D 1 124 ? -20.925 -7.642  6.318   1.00 45.05  ? 124 ARG D CD  1 
ATOM   11339 N NE  . ARG D 1 124 ? -20.700 -6.996  5.025   1.00 52.39  ? 124 ARG D NE  1 
ATOM   11340 C CZ  . ARG D 1 124 ? -21.594 -6.911  4.057   1.00 54.19  ? 124 ARG D CZ  1 
ATOM   11341 N NH1 . ARG D 1 124 ? -22.859 -7.230  4.272   1.00 57.91  ? 124 ARG D NH1 1 
ATOM   11342 N NH2 . ARG D 1 124 ? -21.227 -6.454  2.892   1.00 61.04  ? 124 ARG D NH2 1 
ATOM   11343 N N   . VAL D 1 125 ? -18.943 -3.810  10.260  1.00 42.63  ? 125 VAL D N   1 
ATOM   11344 C CA  . VAL D 1 125 ? -18.609 -2.402  10.508  1.00 45.34  ? 125 VAL D CA  1 
ATOM   11345 C C   . VAL D 1 125 ? -17.151 -2.294  10.910  1.00 41.00  ? 125 VAL D C   1 
ATOM   11346 O O   . VAL D 1 125 ? -16.717 -2.983  11.801  1.00 46.25  ? 125 VAL D O   1 
ATOM   11347 C CB  . VAL D 1 125 ? -19.505 -1.770  11.580  1.00 52.16  ? 125 VAL D CB  1 
ATOM   11348 C CG1 . VAL D 1 125 ? -18.780 -0.695  12.371  1.00 61.76  ? 125 VAL D CG1 1 
ATOM   11349 C CG2 . VAL D 1 125 ? -20.751 -1.204  10.978  1.00 55.82  ? 125 VAL D CG2 1 
ATOM   11350 N N   . HIS D 1 126 ? -16.431 -1.378  10.266  1.00 46.07  ? 126 HIS D N   1 
ATOM   11351 C CA  . HIS D 1 126 ? -14.982 -1.287  10.569  1.00 53.72  ? 126 HIS D CA  1 
ATOM   11352 C C   . HIS D 1 126 ? -14.475 0.150   10.454  1.00 49.12  ? 126 HIS D C   1 
ATOM   11353 O O   . HIS D 1 126 ? -14.765 0.834   9.451   1.00 44.56  ? 126 HIS D O   1 
ATOM   11354 C CB  . HIS D 1 126 ? -14.190 -2.299  9.724   1.00 64.24  ? 126 HIS D CB  1 
ATOM   11355 C CG  . HIS D 1 126 ? -13.529 -1.745  8.510   1.00 74.61  ? 126 HIS D CG  1 
ATOM   11356 N ND1 . HIS D 1 126 ? -12.256 -1.219  8.524   1.00 92.04  ? 126 HIS D ND1 1 
ATOM   11357 C CD2 . HIS D 1 126 ? -13.959 -1.642  7.249   1.00 100.02 ? 126 HIS D CD2 1 
ATOM   11358 C CE1 . HIS D 1 126 ? -11.940 -0.810  7.304   1.00 95.98  ? 126 HIS D CE1 1 
ATOM   11359 N NE2 . HIS D 1 126 ? -12.961 -1.057  6.514   1.00 106.38 ? 126 HIS D NE2 1 
ATOM   11360 N N   . GLY D 1 127 ? -13.794 0.620   11.496  1.00 46.89  ? 127 GLY D N   1 
ATOM   11361 C CA  . GLY D 1 127 ? -13.107 1.902   11.454  1.00 44.14  ? 127 GLY D CA  1 
ATOM   11362 C C   . GLY D 1 127 ? -11.791 1.781   10.698  1.00 42.27  ? 127 GLY D C   1 
ATOM   11363 O O   . GLY D 1 127 ? -11.483 0.729   10.200  1.00 42.33  ? 127 GLY D O   1 
ATOM   11364 N N   . ARG D 1 128 ? -10.992 2.866   10.681  1.00 43.69  ? 128 ARG D N   1 
ATOM   11365 C CA  . ARG D 1 128 ? -9.778  2.918   9.874   1.00 45.57  ? 128 ARG D CA  1 
ATOM   11366 C C   . ARG D 1 128 ? -8.638  3.509   10.689  1.00 44.17  ? 128 ARG D C   1 
ATOM   11367 O O   . ARG D 1 128 ? -8.868  4.317   11.584  1.00 46.41  ? 128 ARG D O   1 
ATOM   11368 C CB  . ARG D 1 128 ? -10.006 3.725   8.592   1.00 53.57  ? 128 ARG D CB  1 
ATOM   11369 C CG  . ARG D 1 128 ? -10.709 2.933   7.488   1.00 65.61  ? 128 ARG D CG  1 
ATOM   11370 C CD  . ARG D 1 128 ? -10.918 3.728   6.163   1.00 63.09  ? 128 ARG D CD  1 
ATOM   11371 N NE  . ARG D 1 128 ? -11.303 5.137   6.363   1.00 69.47  ? 128 ARG D NE  1 
ATOM   11372 C CZ  . ARG D 1 128 ? -12.509 5.611   6.789   1.00 71.30  ? 128 ARG D CZ  1 
ATOM   11373 N NH1 . ARG D 1 128 ? -13.505 4.786   7.106   1.00 76.18  ? 128 ARG D NH1 1 
ATOM   11374 N NH2 . ARG D 1 128 ? -12.689 6.915   6.911   1.00 73.98  ? 128 ARG D NH2 1 
ATOM   11375 N N   . ILE D 1 129 ? -7.403  3.073   10.376  1.00 41.55  ? 129 ILE D N   1 
ATOM   11376 C CA  . ILE D 1 129 ? -6.195  3.703   10.903  1.00 45.01  ? 129 ILE D CA  1 
ATOM   11377 C C   . ILE D 1 129 ? -5.380  4.232   9.732   1.00 46.92  ? 129 ILE D C   1 
ATOM   11378 O O   . ILE D 1 129 ? -5.058  3.486   8.811   1.00 49.78  ? 129 ILE D O   1 
ATOM   11379 C CB  . ILE D 1 129 ? -5.375  2.723   11.767  1.00 46.92  ? 129 ILE D CB  1 
ATOM   11380 C CG1 . ILE D 1 129 ? -6.104  2.353   13.054  1.00 50.92  ? 129 ILE D CG1 1 
ATOM   11381 C CG2 . ILE D 1 129 ? -3.988  3.294   12.063  1.00 50.24  ? 129 ILE D CG2 1 
ATOM   11382 C CD1 . ILE D 1 129 ? -5.429  1.250   13.857  1.00 49.28  ? 129 ILE D CD1 1 
ATOM   11383 N N   . VAL D 1 130 ? -5.039  5.521   9.782   1.00 56.41  ? 130 VAL D N   1 
ATOM   11384 C CA  . VAL D 1 130 ? -4.512  6.222   8.614   1.00 56.18  ? 130 VAL D CA  1 
ATOM   11385 C C   . VAL D 1 130 ? -3.109  6.724   8.911   1.00 56.72  ? 130 VAL D C   1 
ATOM   11386 O O   . VAL D 1 130 ? -2.770  7.046   10.060  1.00 49.53  ? 130 VAL D O   1 
ATOM   11387 C CB  . VAL D 1 130 ? -5.459  7.359   8.189   1.00 61.31  ? 130 VAL D CB  1 
ATOM   11388 C CG1 . VAL D 1 130 ? -4.770  8.392   7.293   1.00 66.09  ? 130 VAL D CG1 1 
ATOM   11389 C CG2 . VAL D 1 130 ? -6.716  6.800   7.506   1.00 56.66  ? 130 VAL D CG2 1 
ATOM   11390 N N   . GLU D 1 131 ? -2.292  6.772   7.858   1.00 75.10  ? 131 GLU D N   1 
ATOM   11391 C CA  . GLU D 1 131 ? -0.893  7.182   7.969   1.00 85.96  ? 131 GLU D CA  1 
ATOM   11392 C C   . GLU D 1 131 ? -0.828  8.700   8.108   1.00 73.26  ? 131 GLU D C   1 
ATOM   11393 O O   . GLU D 1 131 ? -1.713  9.407   7.626   1.00 75.11  ? 131 GLU D O   1 
ATOM   11394 C CB  . GLU D 1 131 ? -0.090  6.741   6.737   1.00 92.01  ? 131 GLU D CB  1 
ATOM   11395 C CG  . GLU D 1 131 ? -0.131  5.238   6.463   1.00 93.22  ? 131 GLU D CG  1 
ATOM   11396 C CD  . GLU D 1 131 ? 0.450   4.356   7.562   1.00 104.18 ? 131 GLU D CD  1 
ATOM   11397 O OE1 . GLU D 1 131 ? -0.138  3.268   7.821   1.00 116.40 ? 131 GLU D OE1 1 
ATOM   11398 O OE2 . GLU D 1 131 ? 1.476   4.756   8.172   1.00 112.99 ? 131 GLU D OE2 1 
ATOM   11399 N N   . SER D 1 132 ? 0.232   9.190   8.752   1.00 61.47  ? 132 SER D N   1 
ATOM   11400 C CA  . SER D 1 132 ? 0.420   10.621  8.926   1.00 61.34  ? 132 SER D CA  1 
ATOM   11401 C C   . SER D 1 132 ? 1.869   10.997  8.638   1.00 59.86  ? 132 SER D C   1 
ATOM   11402 O O   . SER D 1 132 ? 2.781   10.303  9.068   1.00 60.14  ? 132 SER D O   1 
ATOM   11403 C CB  . SER D 1 132 ? 0.012   11.047  10.322  1.00 58.68  ? 132 SER D CB  1 
ATOM   11404 O OG  . SER D 1 132 ? 0.670   12.244  10.719  1.00 56.07  ? 132 SER D OG  1 
ATOM   11405 N N   . ASP D 1 133 ? 2.059   12.148  7.973   1.00 60.45  ? 133 ASP D N   1 
ATOM   11406 C CA  . ASP D 1 133 ? 3.389   12.674  7.689   1.00 60.75  ? 133 ASP D CA  1 
ATOM   11407 C C   . ASP D 1 133 ? 4.008   13.286  8.936   1.00 65.06  ? 133 ASP D C   1 
ATOM   11408 O O   . ASP D 1 133 ? 5.228   13.341  9.050   1.00 76.75  ? 133 ASP D O   1 
ATOM   11409 C CB  . ASP D 1 133 ? 3.373   13.709  6.580   1.00 56.44  ? 133 ASP D CB  1 
ATOM   11410 C CG  . ASP D 1 133 ? 3.597   13.158  5.188   1.00 56.39  ? 133 ASP D CG  1 
ATOM   11411 O OD1 . ASP D 1 133 ? 4.502   12.306  5.036   1.00 67.13  ? 133 ASP D OD1 1 
ATOM   11412 O OD2 . ASP D 1 133 ? 2.888   13.596  4.269   1.00 47.52  ? 133 ASP D OD2 1 
ATOM   11413 N N   . VAL D 1 134 ? 3.177   13.800  9.839   1.00 66.26  ? 134 VAL D N   1 
ATOM   11414 C CA  . VAL D 1 134 ? 3.688   14.413  11.060  1.00 70.36  ? 134 VAL D CA  1 
ATOM   11415 C C   . VAL D 1 134 ? 4.269   13.309  11.958  1.00 68.13  ? 134 VAL D C   1 
ATOM   11416 O O   . VAL D 1 134 ? 3.590   12.311  12.244  1.00 62.01  ? 134 VAL D O   1 
ATOM   11417 C CB  . VAL D 1 134 ? 2.606   15.224  11.802  1.00 69.70  ? 134 VAL D CB  1 
ATOM   11418 C CG1 . VAL D 1 134 ? 3.119   15.744  13.138  1.00 68.03  ? 134 VAL D CG1 1 
ATOM   11419 C CG2 . VAL D 1 134 ? 2.068   16.365  10.949  1.00 64.21  ? 134 VAL D CG2 1 
ATOM   11420 N N   . PRO D 1 135 ? 5.529   13.453  12.438  1.00 69.81  ? 135 PRO D N   1 
ATOM   11421 C CA  . PRO D 1 135 ? 6.151   12.433  13.289  1.00 77.85  ? 135 PRO D CA  1 
ATOM   11422 C C   . PRO D 1 135 ? 5.449   12.310  14.634  1.00 77.73  ? 135 PRO D C   1 
ATOM   11423 O O   . PRO D 1 135 ? 5.139   13.323  15.277  1.00 74.67  ? 135 PRO D O   1 
ATOM   11424 C CB  . PRO D 1 135 ? 7.618   12.907  13.447  1.00 76.80  ? 135 PRO D CB  1 
ATOM   11425 C CG  . PRO D 1 135 ? 7.794   13.962  12.349  1.00 76.27  ? 135 PRO D CG  1 
ATOM   11426 C CD  . PRO D 1 135 ? 6.427   14.575  12.157  1.00 72.72  ? 135 PRO D CD  1 
ATOM   11427 N N   . GLY D 1 136 ? 5.177   11.058  15.032  1.00 70.52  ? 136 GLY D N   1 
ATOM   11428 C CA  . GLY D 1 136 ? 4.573   10.761  16.326  1.00 69.77  ? 136 GLY D CA  1 
ATOM   11429 C C   . GLY D 1 136 ? 3.027   10.885  16.320  1.00 69.46  ? 136 GLY D C   1 
ATOM   11430 O O   . GLY D 1 136 ? 2.402   10.742  17.371  1.00 69.21  ? 136 GLY D O   1 
ATOM   11431 N N   . LYS D 1 137 ? 2.419   11.144  15.138  1.00 60.48  ? 137 LYS D N   1 
ATOM   11432 C CA  . LYS D 1 137 ? 0.977   11.351  15.047  1.00 60.80  ? 137 LYS D CA  1 
ATOM   11433 C C   . LYS D 1 137 ? 0.303   10.114  14.429  1.00 60.86  ? 137 LYS D C   1 
ATOM   11434 O O   . LYS D 1 137 ? 0.678   9.671   13.351  1.00 56.96  ? 137 LYS D O   1 
ATOM   11435 C CB  . LYS D 1 137 ? 0.649   12.599  14.229  1.00 59.79  ? 137 LYS D CB  1 
ATOM   11436 C CG  . LYS D 1 137 ? -0.847  12.817  13.975  1.00 58.86  ? 137 LYS D CG  1 
ATOM   11437 C CD  . LYS D 1 137 ? -1.162  14.057  13.146  1.00 67.36  ? 137 LYS D CD  1 
ATOM   11438 C CE  . LYS D 1 137 ? -0.492  15.313  13.664  1.00 71.79  ? 137 LYS D CE  1 
ATOM   11439 N NZ  . LYS D 1 137 ? -0.703  15.519  15.108  1.00 75.29  ? 137 LYS D NZ  1 
ATOM   11440 N N   . GLU D 1 138 ? -0.731  9.610   15.120  1.00 60.73  ? 138 GLU D N   1 
ATOM   11441 C CA  . GLU D 1 138 ? -1.566  8.503   14.646  1.00 59.56  ? 138 GLU D CA  1 
ATOM   11442 C C   . GLU D 1 138 ? -2.991  9.027   14.444  1.00 55.53  ? 138 GLU D C   1 
ATOM   11443 O O   . GLU D 1 138 ? -3.541  9.666   15.339  1.00 55.88  ? 138 GLU D O   1 
ATOM   11444 C CB  . GLU D 1 138 ? -1.471  7.379   15.697  1.00 65.53  ? 138 GLU D CB  1 
ATOM   11445 C CG  . GLU D 1 138 ? -2.552  6.290   15.619  1.00 64.76  ? 138 GLU D CG  1 
ATOM   11446 C CD  . GLU D 1 138 ? -2.470  5.218   16.757  1.00 59.31  ? 138 GLU D CD  1 
ATOM   11447 O OE1 . GLU D 1 138 ? -1.810  5.498   17.783  1.00 54.62  ? 138 GLU D OE1 1 
ATOM   11448 O OE2 . GLU D 1 138 ? -3.075  4.112   16.625  1.00 44.99  ? 138 GLU D OE2 1 
ATOM   11449 N N   . SER D 1 139 ? -3.565  8.787   13.248  1.00 51.17  ? 139 SER D N   1 
ATOM   11450 C CA  . SER D 1 139 ? -4.938  9.192   12.954  1.00 50.85  ? 139 SER D CA  1 
ATOM   11451 C C   . SER D 1 139 ? -5.840  7.962   12.932  1.00 56.99  ? 139 SER D C   1 
ATOM   11452 O O   . SER D 1 139 ? -5.600  7.030   12.175  1.00 61.41  ? 139 SER D O   1 
ATOM   11453 C CB  . SER D 1 139 ? -5.026  9.964   11.670  1.00 50.70  ? 139 SER D CB  1 
ATOM   11454 O OG  . SER D 1 139 ? -4.236  9.357   10.666  1.00 68.30  ? 139 SER D OG  1 
ATOM   11455 N N   . ARG D 1 140 ? -6.848  7.965   13.817  1.00 57.66  ? 140 ARG D N   1 
ATOM   11456 C CA  . ARG D 1 140 ? -7.800  6.874   13.944  1.00 51.52  ? 140 ARG D CA  1 
ATOM   11457 C C   . ARG D 1 140 ? -9.179  7.387   13.581  1.00 52.20  ? 140 ARG D C   1 
ATOM   11458 O O   . ARG D 1 140 ? -9.589  8.441   14.059  1.00 63.69  ? 140 ARG D O   1 
ATOM   11459 C CB  . ARG D 1 140 ? -7.837  6.359   15.380  1.00 51.40  ? 140 ARG D CB  1 
ATOM   11460 C CG  . ARG D 1 140 ? -6.471  6.252   16.027  1.00 52.76  ? 140 ARG D CG  1 
ATOM   11461 C CD  . ARG D 1 140 ? -6.348  5.053   16.906  1.00 52.37  ? 140 ARG D CD  1 
ATOM   11462 N NE  . ARG D 1 140 ? -6.897  5.327   18.221  1.00 53.53  ? 140 ARG D NE  1 
ATOM   11463 C CZ  . ARG D 1 140 ? -6.206  5.346   19.340  1.00 53.82  ? 140 ARG D CZ  1 
ATOM   11464 N NH1 . ARG D 1 140 ? -4.894  5.161   19.330  1.00 52.72  ? 140 ARG D NH1 1 
ATOM   11465 N NH2 . ARG D 1 140 ? -6.833  5.548   20.474  1.00 55.36  ? 140 ARG D NH2 1 
ATOM   11466 N N   . VAL D 1 141 ? -9.886  6.637   12.730  1.00 49.01  ? 141 VAL D N   1 
ATOM   11467 C CA  . VAL D 1 141 ? -11.247 6.984   12.351  1.00 48.58  ? 141 VAL D CA  1 
ATOM   11468 C C   . VAL D 1 141 ? -12.199 5.947   12.954  1.00 45.68  ? 141 VAL D C   1 
ATOM   11469 O O   . VAL D 1 141 ? -12.094 4.764   12.662  1.00 46.20  ? 141 VAL D O   1 
ATOM   11470 C CB  . VAL D 1 141 ? -11.404 7.075   10.829  1.00 49.86  ? 141 VAL D CB  1 
ATOM   11471 C CG1 . VAL D 1 141 ? -12.649 7.846   10.438  1.00 53.05  ? 141 VAL D CG1 1 
ATOM   11472 C CG2 . VAL D 1 141 ? -10.182 7.688   10.182  1.00 49.30  ? 141 VAL D CG2 1 
ATOM   11473 N N   . TYR D 1 142 ? -13.105 6.416   13.823  1.00 46.77  ? 142 TYR D N   1 
ATOM   11474 C CA  . TYR D 1 142 ? -14.075 5.557   14.494  1.00 46.27  ? 142 TYR D CA  1 
ATOM   11475 C C   . TYR D 1 142 ? -15.415 5.640   13.768  1.00 43.76  ? 142 TYR D C   1 
ATOM   11476 O O   . TYR D 1 142 ? -15.897 6.735   13.455  1.00 45.90  ? 142 TYR D O   1 
ATOM   11477 C CB  . TYR D 1 142 ? -14.210 5.973   15.956  1.00 46.99  ? 142 TYR D CB  1 
ATOM   11478 C CG  . TYR D 1 142 ? -13.014 5.607   16.811  1.00 45.32  ? 142 TYR D CG  1 
ATOM   11479 C CD1 . TYR D 1 142 ? -12.880 4.329   17.347  1.00 45.82  ? 142 TYR D CD1 1 
ATOM   11480 C CD2 . TYR D 1 142 ? -12.015 6.534   17.084  1.00 44.59  ? 142 TYR D CD2 1 
ATOM   11481 C CE1 . TYR D 1 142 ? -11.786 3.984   18.130  1.00 46.26  ? 142 TYR D CE1 1 
ATOM   11482 C CE2 . TYR D 1 142 ? -10.913 6.206   17.865  1.00 39.64  ? 142 TYR D CE2 1 
ATOM   11483 C CZ  . TYR D 1 142 ? -10.796 4.925   18.385  1.00 44.23  ? 142 TYR D CZ  1 
ATOM   11484 O OH  . TYR D 1 142 ? -9.721  4.576   19.143  1.00 46.60  ? 142 TYR D OH  1 
ATOM   11485 N N   . ARG D 1 143 ? -15.993 4.468   13.474  1.00 43.65  ? 143 ARG D N   1 
ATOM   11486 C CA  . ARG D 1 143 ? -17.268 4.391   12.782  1.00 43.88  ? 143 ARG D CA  1 
ATOM   11487 C C   . ARG D 1 143 ? -18.318 3.990   13.797  1.00 42.10  ? 143 ARG D C   1 
ATOM   11488 O O   . ARG D 1 143 ? -18.201 2.944   14.423  1.00 39.07  ? 143 ARG D O   1 
ATOM   11489 C CB  . ARG D 1 143 ? -17.194 3.402   11.614  1.00 45.51  ? 143 ARG D CB  1 
ATOM   11490 C CG  . ARG D 1 143 ? -18.423 3.392   10.713  1.00 46.01  ? 143 ARG D CG  1 
ATOM   11491 C CD  . ARG D 1 143 ? -18.141 2.743   9.400   1.00 49.14  ? 143 ARG D CD  1 
ATOM   11492 N NE  . ARG D 1 143 ? -17.468 3.655   8.475   1.00 51.93  ? 143 ARG D NE  1 
ATOM   11493 C CZ  . ARG D 1 143 ? -17.653 3.691   7.172   1.00 59.99  ? 143 ARG D CZ  1 
ATOM   11494 N NH1 . ARG D 1 143 ? -18.519 2.872   6.587   1.00 68.52  ? 143 ARG D NH1 1 
ATOM   11495 N NH2 . ARG D 1 143 ? -16.954 4.537   6.443   1.00 61.95  ? 143 ARG D NH2 1 
ATOM   11496 N N   . SER D 1 144 ? -19.298 4.868   14.008  1.00 43.83  ? 144 SER D N   1 
ATOM   11497 C CA  . SER D 1 144 ? -20.329 4.645   15.021  1.00 47.71  ? 144 SER D CA  1 
ATOM   11498 C C   . SER D 1 144 ? -21.716 4.947   14.441  1.00 40.63  ? 144 SER D C   1 
ATOM   11499 O O   . SER D 1 144 ? -21.838 5.546   13.363  1.00 42.61  ? 144 SER D O   1 
ATOM   11500 C CB  . SER D 1 144 ? -20.066 5.474   16.239  1.00 49.26  ? 144 SER D CB  1 
ATOM   11501 O OG  . SER D 1 144 ? -20.008 6.850   15.890  1.00 59.40  ? 144 SER D OG  1 
ATOM   11502 N N   . ALA D 1 145 ? -22.753 4.544   15.181  1.00 37.72  ? 145 ALA D N   1 
ATOM   11503 C CA  . ALA D 1 145 ? -24.133 4.793   14.786  1.00 40.75  ? 145 ALA D CA  1 
ATOM   11504 C C   . ALA D 1 145 ? -24.403 6.295   14.748  1.00 38.94  ? 145 ALA D C   1 
ATOM   11505 O O   . ALA D 1 145 ? -23.810 7.044   15.499  1.00 45.35  ? 145 ALA D O   1 
ATOM   11506 C CB  . ALA D 1 145 ? -25.062 4.099   15.732  1.00 41.55  ? 145 ALA D CB  1 
ATOM   11507 N N   . ILE D 1 146 ? -25.309 6.712   13.871  1.00 38.38  ? 146 ILE D N   1 
ATOM   11508 C CA  . ILE D 1 146 ? -25.675 8.118   13.762  1.00 40.85  ? 146 ILE D CA  1 
ATOM   11509 C C   . ILE D 1 146 ? -26.355 8.561   15.051  1.00 38.15  ? 146 ILE D C   1 
ATOM   11510 O O   . ILE D 1 146 ? -26.037 9.602   15.582  1.00 39.75  ? 146 ILE D O   1 
ATOM   11511 C CB  . ILE D 1 146 ? -26.576 8.366   12.551  1.00 42.58  ? 146 ILE D CB  1 
ATOM   11512 C CG1 . ILE D 1 146 ? -25.902 7.935   11.260  1.00 48.28  ? 146 ILE D CG1 1 
ATOM   11513 C CG2 . ILE D 1 146 ? -27.011 9.827   12.496  1.00 43.33  ? 146 ILE D CG2 1 
ATOM   11514 C CD1 . ILE D 1 146 ? -26.780 8.053   10.019  1.00 47.44  ? 146 ILE D CD1 1 
ATOM   11515 N N   . GLY D 1 147 ? -27.295 7.752   15.535  1.00 39.35  ? 147 GLY D N   1 
ATOM   11516 C CA  . GLY D 1 147 ? -28.074 8.085   16.725  1.00 40.62  ? 147 GLY D CA  1 
ATOM   11517 C C   . GLY D 1 147 ? -29.548 7.699   16.548  1.00 41.06  ? 147 GLY D C   1 
ATOM   11518 O O   . GLY D 1 147 ? -29.928 6.521   16.727  1.00 37.98  ? 147 GLY D O   1 
ATOM   11519 N N   . VAL D 1 148 ? -30.366 8.681   16.158  1.00 39.21  ? 148 VAL D N   1 
ATOM   11520 C CA  . VAL D 1 148 ? -31.774 8.439   15.896  1.00 38.72  ? 148 VAL D CA  1 
ATOM   11521 C C   . VAL D 1 148 ? -32.049 8.704   14.424  1.00 39.16  ? 148 VAL D C   1 
ATOM   11522 O O   . VAL D 1 148 ? -31.650 9.755   13.882  1.00 38.40  ? 148 VAL D O   1 
ATOM   11523 C CB  . VAL D 1 148 ? -32.687 9.293   16.779  1.00 42.70  ? 148 VAL D CB  1 
ATOM   11524 C CG1 . VAL D 1 148 ? -34.165 9.064   16.425  1.00 44.57  ? 148 VAL D CG1 1 
ATOM   11525 C CG2 . VAL D 1 148 ? -32.430 9.050   18.280  1.00 42.89  ? 148 VAL D CG2 1 
ATOM   11526 N N   . VAL D 1 149 ? -32.755 7.752   13.790  1.00 39.75  ? 149 VAL D N   1 
ATOM   11527 C CA  . VAL D 1 149 ? -33.174 7.887   12.400  1.00 41.20  ? 149 VAL D CA  1 
ATOM   11528 C C   . VAL D 1 149 ? -34.693 7.958   12.358  1.00 40.13  ? 149 VAL D C   1 
ATOM   11529 O O   . VAL D 1 149 ? -35.368 7.057   12.857  1.00 37.77  ? 149 VAL D O   1 
ATOM   11530 C CB  . VAL D 1 149 ? -32.667 6.719   11.526  1.00 40.02  ? 149 VAL D CB  1 
ATOM   11531 C CG1 . VAL D 1 149 ? -33.076 6.886   10.076  1.00 36.81  ? 149 VAL D CG1 1 
ATOM   11532 C CG2 . VAL D 1 149 ? -31.162 6.537   11.627  1.00 43.82  ? 149 VAL D CG2 1 
ATOM   11533 N N   . GLY D 1 150 ? -35.210 8.999   11.692  1.00 40.08  ? 150 GLY D N   1 
ATOM   11534 C CA  . GLY D 1 150 ? -36.630 9.121   11.425  1.00 41.32  ? 150 GLY D CA  1 
ATOM   11535 C C   . GLY D 1 150 ? -36.966 8.621   10.024  1.00 42.10  ? 150 GLY D C   1 
ATOM   11536 O O   . GLY D 1 150 ? -36.377 9.075   9.034   1.00 42.12  ? 150 GLY D O   1 
ATOM   11537 N N   . VAL D 1 151 ? -37.921 7.689   9.954   1.00 38.91  ? 151 VAL D N   1 
ATOM   11538 C CA  . VAL D 1 151 ? -38.282 7.040   8.702   1.00 38.14  ? 151 VAL D CA  1 
ATOM   11539 C C   . VAL D 1 151 ? -39.722 7.397   8.345   1.00 34.37  ? 151 VAL D C   1 
ATOM   11540 O O   . VAL D 1 151 ? -40.629 7.128   9.105   1.00 35.98  ? 151 VAL D O   1 
ATOM   11541 C CB  . VAL D 1 151 ? -38.087 5.511   8.818   1.00 33.23  ? 151 VAL D CB  1 
ATOM   11542 C CG1 . VAL D 1 151 ? -38.460 4.792   7.527   1.00 31.63  ? 151 VAL D CG1 1 
ATOM   11543 C CG2 . VAL D 1 151 ? -36.670 5.162   9.233   1.00 33.23  ? 151 VAL D CG2 1 
ATOM   11544 N N   . ILE D 1 152 ? -39.908 7.963   7.158   1.00 36.65  ? 152 ILE D N   1 
ATOM   11545 C CA  . ILE D 1 152 ? -41.232 8.196   6.607   1.00 39.35  ? 152 ILE D CA  1 
ATOM   11546 C C   . ILE D 1 152 ? -41.585 7.071   5.622   1.00 39.75  ? 152 ILE D C   1 
ATOM   11547 O O   . ILE D 1 152 ? -40.857 6.838   4.674   1.00 34.99  ? 152 ILE D O   1 
ATOM   11548 C CB  . ILE D 1 152 ? -41.292 9.569   5.945   1.00 38.04  ? 152 ILE D CB  1 
ATOM   11549 C CG1 . ILE D 1 152 ? -40.900 10.675  6.949   1.00 40.88  ? 152 ILE D CG1 1 
ATOM   11550 C CG2 . ILE D 1 152 ? -42.674 9.819   5.325   1.00 35.39  ? 152 ILE D CG2 1 
ATOM   11551 C CD1 . ILE D 1 152 ? -40.333 11.928  6.306   1.00 42.12  ? 152 ILE D CD1 1 
ATOM   11552 N N   . SER D 1 153 ? -42.747 6.418   5.862   1.00 41.93  ? 153 SER D N   1 
ATOM   11553 C CA  . SER D 1 153 ? -43.175 5.243   5.115   1.00 41.85  ? 153 SER D CA  1 
ATOM   11554 C C   . SER D 1 153 ? -44.088 5.667   3.987   1.00 40.07  ? 153 SER D C   1 
ATOM   11555 O O   . SER D 1 153 ? -44.946 6.513   4.182   1.00 42.61  ? 153 SER D O   1 
ATOM   11556 C CB  . SER D 1 153 ? -43.903 4.256   5.997   1.00 44.21  ? 153 SER D CB  1 
ATOM   11557 O OG  . SER D 1 153 ? -43.125 3.849   7.082   1.00 48.90  ? 153 SER D OG  1 
ATOM   11558 N N   . PRO D 1 154 ? -44.021 5.002   2.818   1.00 44.57  ? 154 PRO D N   1 
ATOM   11559 C CA  . PRO D 1 154 ? -45.003 5.220   1.746   1.00 45.04  ? 154 PRO D CA  1 
ATOM   11560 C C   . PRO D 1 154 ? -46.254 4.333   1.882   1.00 48.04  ? 154 PRO D C   1 
ATOM   11561 O O   . PRO D 1 154 ? -46.268 3.351   2.652   1.00 50.69  ? 154 PRO D O   1 
ATOM   11562 C CB  . PRO D 1 154 ? -44.151 4.858   0.517   1.00 37.78  ? 154 PRO D CB  1 
ATOM   11563 C CG  . PRO D 1 154 ? -43.293 3.703   1.002   1.00 39.31  ? 154 PRO D CG  1 
ATOM   11564 C CD  . PRO D 1 154 ? -43.005 3.997   2.466   1.00 40.02  ? 154 PRO D CD  1 
ATOM   11565 N N   . TRP D 1 155 ? -47.267 4.633   1.084   1.00 42.79  ? 155 TRP D N   1 
ATOM   11566 C CA  . TRP D 1 155 ? -48.468 3.809   1.054   1.00 55.17  ? 155 TRP D CA  1 
ATOM   11567 C C   . TRP D 1 155 ? -48.294 2.633   0.087   1.00 52.57  ? 155 TRP D C   1 
ATOM   11568 O O   . TRP D 1 155 ? -49.044 1.657   0.175   1.00 51.46  ? 155 TRP D O   1 
ATOM   11569 C CB  . TRP D 1 155 ? -49.708 4.647   0.694   1.00 56.82  ? 155 TRP D CB  1 
ATOM   11570 C CG  . TRP D 1 155 ? -49.503 5.571   -0.471  1.00 60.58  ? 155 TRP D CG  1 
ATOM   11571 C CD1 . TRP D 1 155 ? -49.167 6.890   -0.415  1.00 62.08  ? 155 TRP D CD1 1 
ATOM   11572 C CD2 . TRP D 1 155 ? -49.622 5.240   -1.877  1.00 66.21  ? 155 TRP D CD2 1 
ATOM   11573 N NE1 . TRP D 1 155 ? -49.043 7.403   -1.682  1.00 71.09  ? 155 TRP D NE1 1 
ATOM   11574 C CE2 . TRP D 1 155 ? -49.331 6.420   -2.599  1.00 69.25  ? 155 TRP D CE2 1 
ATOM   11575 C CE3 . TRP D 1 155 ? -49.958 4.073   -2.591  1.00 66.26  ? 155 TRP D CE3 1 
ATOM   11576 C CZ2 . TRP D 1 155 ? -49.352 6.461   -4.000  1.00 75.16  ? 155 TRP D CZ2 1 
ATOM   11577 C CZ3 . TRP D 1 155 ? -50.003 4.121   -3.972  1.00 71.46  ? 155 TRP D CZ3 1 
ATOM   11578 C CH2 . TRP D 1 155 ? -49.692 5.297   -4.667  1.00 71.88  ? 155 TRP D CH2 1 
ATOM   11579 N N   . ASN D 1 156 ? -47.289 2.722   -0.816  1.00 54.25  ? 156 ASN D N   1 
ATOM   11580 C CA  . ASN D 1 156 ? -47.167 1.790   -1.935  1.00 64.84  ? 156 ASN D CA  1 
ATOM   11581 C C   . ASN D 1 156 ? -46.747 0.401   -1.436  1.00 64.93  ? 156 ASN D C   1 
ATOM   11582 O O   . ASN D 1 156 ? -47.525 -0.571  -1.529  1.00 77.13  ? 156 ASN D O   1 
ATOM   11583 C CB  . ASN D 1 156 ? -46.234 2.319   -3.017  1.00 79.56  ? 156 ASN D CB  1 
ATOM   11584 C CG  . ASN D 1 156 ? -46.597 1.775   -4.382  1.00 92.95  ? 156 ASN D CG  1 
ATOM   11585 O OD1 . ASN D 1 156 ? -47.786 1.675   -4.715  1.00 100.73 ? 156 ASN D OD1 1 
ATOM   11586 N ND2 . ASN D 1 156 ? -45.602 1.406   -5.177  1.00 111.60 ? 156 ASN D ND2 1 
ATOM   11587 N N   . PHE D 1 157 ? -45.523 0.296   -0.943  1.00 56.35  ? 157 PHE D N   1 
ATOM   11588 C CA  . PHE D 1 157 ? -45.009 -0.981  -0.428  1.00 54.35  ? 157 PHE D CA  1 
ATOM   11589 C C   . PHE D 1 157 ? -44.604 -0.810  1.026   1.00 46.05  ? 157 PHE D C   1 
ATOM   11590 O O   . PHE D 1 157 ? -43.431 -0.851  1.336   1.00 40.12  ? 157 PHE D O   1 
ATOM   11591 C CB  . PHE D 1 157 ? -43.763 -1.434  -1.177  1.00 60.76  ? 157 PHE D CB  1 
ATOM   11592 C CG  . PHE D 1 157 ? -43.986 -2.444  -2.276  1.00 74.06  ? 157 PHE D CG  1 
ATOM   11593 C CD1 . PHE D 1 157 ? -43.910 -3.812  -2.010  1.00 82.43  ? 157 PHE D CD1 1 
ATOM   11594 C CD2 . PHE D 1 157 ? -44.174 -2.036  -3.593  1.00 79.26  ? 157 PHE D CD2 1 
ATOM   11595 C CE1 . PHE D 1 157 ? -44.069 -4.748  -3.028  1.00 83.78  ? 157 PHE D CE1 1 
ATOM   11596 C CE2 . PHE D 1 157 ? -44.332 -2.973  -4.609  1.00 85.57  ? 157 PHE D CE2 1 
ATOM   11597 C CZ  . PHE D 1 157 ? -44.267 -4.328  -4.325  1.00 84.33  ? 157 PHE D CZ  1 
ATOM   11598 N N   . PRO D 1 158 ? -45.542 -0.515  1.941   1.00 42.33  ? 158 PRO D N   1 
ATOM   11599 C CA  . PRO D 1 158 ? -45.179 0.008   3.245   1.00 42.55  ? 158 PRO D CA  1 
ATOM   11600 C C   . PRO D 1 158 ? -44.219 -0.909  4.015   1.00 41.12  ? 158 PRO D C   1 
ATOM   11601 O O   . PRO D 1 158 ? -43.201 -0.448  4.535   1.00 40.24  ? 158 PRO D O   1 
ATOM   11602 C CB  . PRO D 1 158 ? -46.551 0.182   3.961   1.00 46.62  ? 158 PRO D CB  1 
ATOM   11603 C CG  . PRO D 1 158 ? -47.497 -0.718  3.174   1.00 46.77  ? 158 PRO D CG  1 
ATOM   11604 C CD  . PRO D 1 158 ? -46.987 -0.666  1.764   1.00 44.93  ? 158 PRO D CD  1 
ATOM   11605 N N   . LEU D 1 159 ? -44.544 -2.206  4.094   1.00 37.22  ? 159 LEU D N   1 
ATOM   11606 C CA  . LEU D 1 159 ? -43.815 -3.088  4.980   1.00 37.00  ? 159 LEU D CA  1 
ATOM   11607 C C   . LEU D 1 159 ? -42.360 -3.246  4.486   1.00 35.54  ? 159 LEU D C   1 
ATOM   11608 O O   . LEU D 1 159 ? -41.416 -3.039  5.236   1.00 29.44  ? 159 LEU D O   1 
ATOM   11609 C CB  . LEU D 1 159 ? -44.531 -4.412  5.118   1.00 35.66  ? 159 LEU D CB  1 
ATOM   11610 C CG  . LEU D 1 159 ? -44.028 -5.304  6.248   1.00 39.86  ? 159 LEU D CG  1 
ATOM   11611 C CD1 . LEU D 1 159 ? -45.153 -5.843  7.024   1.00 42.03  ? 159 LEU D CD1 1 
ATOM   11612 C CD2 . LEU D 1 159 ? -43.194 -6.422  5.718   1.00 47.45  ? 159 LEU D CD2 1 
ATOM   11613 N N   . HIS D 1 160 ? -42.188 -3.548  3.217   1.00 36.05  ? 160 HIS D N   1 
ATOM   11614 C CA  . HIS D 1 160 ? -40.859 -3.850  2.703   1.00 41.64  ? 160 HIS D CA  1 
ATOM   11615 C C   . HIS D 1 160 ? -39.982 -2.594  2.725   1.00 40.78  ? 160 HIS D C   1 
ATOM   11616 O O   . HIS D 1 160 ? -38.820 -2.651  3.109   1.00 36.41  ? 160 HIS D O   1 
ATOM   11617 C CB  . HIS D 1 160 ? -40.951 -4.452  1.313   1.00 46.44  ? 160 HIS D CB  1 
ATOM   11618 C CG  . HIS D 1 160 ? -39.698 -4.372  0.552   1.00 49.78  ? 160 HIS D CG  1 
ATOM   11619 N ND1 . HIS D 1 160 ? -39.681 -3.935  -0.754  1.00 55.12  ? 160 HIS D ND1 1 
ATOM   11620 C CD2 . HIS D 1 160 ? -38.428 -4.658  0.870   1.00 54.07  ? 160 HIS D CD2 1 
ATOM   11621 C CE1 . HIS D 1 160 ? -38.439 -3.968  -1.206  1.00 55.39  ? 160 HIS D CE1 1 
ATOM   11622 N NE2 . HIS D 1 160 ? -37.654 -4.389  -0.234  1.00 48.44  ? 160 HIS D NE2 1 
ATOM   11623 N N   . LEU D 1 161 ? -40.549 -1.460  2.310   1.00 39.14  ? 161 LEU D N   1 
ATOM   11624 C CA  . LEU D 1 161 ? -39.779 -0.231  2.198   1.00 38.45  ? 161 LEU D CA  1 
ATOM   11625 C C   . LEU D 1 161 ? -39.469 0.360   3.591   1.00 37.90  ? 161 LEU D C   1 
ATOM   11626 O O   . LEU D 1 161 ? -38.415 0.935   3.781   1.00 45.78  ? 161 LEU D O   1 
ATOM   11627 C CB  . LEU D 1 161 ? -40.502 0.742   1.274   1.00 37.65  ? 161 LEU D CB  1 
ATOM   11628 C CG  . LEU D 1 161 ? -40.623 0.268   -0.190  1.00 40.89  ? 161 LEU D CG  1 
ATOM   11629 C CD1 . LEU D 1 161 ? -41.173 1.332   -1.129  1.00 40.46  ? 161 LEU D CD1 1 
ATOM   11630 C CD2 . LEU D 1 161 ? -39.278 -0.239  -0.703  1.00 39.69  ? 161 LEU D CD2 1 
ATOM   11631 N N   . THR D 1 162 ? -40.340 0.131   4.575   1.00 35.56  ? 162 THR D N   1 
ATOM   11632 C CA  . THR D 1 162 ? -40.059 0.542   5.944   1.00 32.68  ? 162 THR D CA  1 
ATOM   11633 C C   . THR D 1 162 ? -38.905 -0.294  6.493   1.00 33.41  ? 162 THR D C   1 
ATOM   11634 O O   . THR D 1 162 ? -37.932 0.252   7.029   1.00 30.58  ? 162 THR D O   1 
ATOM   11635 C CB  . THR D 1 162 ? -41.306 0.407   6.822   1.00 36.39  ? 162 THR D CB  1 
ATOM   11636 O OG1 . THR D 1 162 ? -42.326 1.237   6.272   1.00 41.18  ? 162 THR D OG1 1 
ATOM   11637 C CG2 . THR D 1 162 ? -41.060 0.872   8.247   1.00 40.30  ? 162 THR D CG2 1 
ATOM   11638 N N   . GLN D 1 163 ? -39.018 -1.624  6.361   1.00 33.59  ? 163 GLN D N   1 
ATOM   11639 C CA  . GLN D 1 163 ? -38.020 -2.550  6.904   1.00 30.51  ? 163 GLN D CA  1 
ATOM   11640 C C   . GLN D 1 163 ? -36.647 -2.338  6.239   1.00 31.27  ? 163 GLN D C   1 
ATOM   11641 O O   . GLN D 1 163 ? -35.636 -2.565  6.856   1.00 33.49  ? 163 GLN D O   1 
ATOM   11642 C CB  . GLN D 1 163 ? -38.479 -3.990  6.698   1.00 31.62  ? 163 GLN D CB  1 
ATOM   11643 C CG  . GLN D 1 163 ? -37.621 -5.023  7.404   1.00 32.74  ? 163 GLN D CG  1 
ATOM   11644 C CD  . GLN D 1 163 ? -37.872 -5.100  8.895   1.00 36.37  ? 163 GLN D CD  1 
ATOM   11645 O OE1 . GLN D 1 163 ? -38.344 -4.138  9.529   1.00 38.83  ? 163 GLN D OE1 1 
ATOM   11646 N NE2 . GLN D 1 163 ? -37.536 -6.250  9.479   1.00 34.96  ? 163 GLN D NE2 1 
ATOM   11647 N N   . ARG D 1 164 ? -36.637 -1.910  4.970   1.00 35.22  ? 164 ARG D N   1 
ATOM   11648 C CA  . ARG D 1 164 ? -35.402 -1.668  4.244   1.00 36.16  ? 164 ARG D CA  1 
ATOM   11649 C C   . ARG D 1 164 ? -34.529 -0.632  4.979   1.00 36.29  ? 164 ARG D C   1 
ATOM   11650 O O   . ARG D 1 164 ? -33.312 -0.734  4.940   1.00 36.21  ? 164 ARG D O   1 
ATOM   11651 C CB  . ARG D 1 164 ? -35.696 -1.237  2.803   1.00 41.68  ? 164 ARG D CB  1 
ATOM   11652 C CG  . ARG D 1 164 ? -34.463 -1.217  1.915   1.00 47.68  ? 164 ARG D CG  1 
ATOM   11653 C CD  . ARG D 1 164 ? -34.800 -1.301  0.438   1.00 56.43  ? 164 ARG D CD  1 
ATOM   11654 N NE  . ARG D 1 164 ? -35.210 -0.005  -0.099  1.00 68.87  ? 164 ARG D NE  1 
ATOM   11655 C CZ  . ARG D 1 164 ? -34.377 0.954   -0.456  1.00 87.64  ? 164 ARG D CZ  1 
ATOM   11656 N NH1 . ARG D 1 164 ? -33.076 0.696   -0.568  1.00 90.39  ? 164 ARG D NH1 1 
ATOM   11657 N NH2 . ARG D 1 164 ? -34.846 2.164   -0.748  1.00 93.23  ? 164 ARG D NH2 1 
ATOM   11658 N N   . SER D 1 165 ? -35.153 0.367   5.640   1.00 36.28  ? 165 SER D N   1 
ATOM   11659 C CA  . SER D 1 165 ? -34.399 1.331   6.459   1.00 35.38  ? 165 SER D CA  1 
ATOM   11660 C C   . SER D 1 165 ? -34.292 0.853   7.905   1.00 34.89  ? 165 SER D C   1 
ATOM   11661 O O   . SER D 1 165 ? -33.258 1.004   8.530   1.00 35.23  ? 165 SER D O   1 
ATOM   11662 C CB  . SER D 1 165 ? -34.998 2.705   6.411   1.00 36.00  ? 165 SER D CB  1 
ATOM   11663 O OG  . SER D 1 165 ? -35.131 3.154   5.068   1.00 41.53  ? 165 SER D OG  1 
ATOM   11664 N N   . ILE D 1 166 ? -35.383 0.325   8.429   1.00 35.64  ? 166 ILE D N   1 
ATOM   11665 C CA  . ILE D 1 166 ? -35.493 0.007   9.847   1.00 39.17  ? 166 ILE D CA  1 
ATOM   11666 C C   . ILE D 1 166 ? -34.463 -1.069  10.221  1.00 37.86  ? 166 ILE D C   1 
ATOM   11667 O O   . ILE D 1 166 ? -33.719 -0.898  11.178  1.00 34.01  ? 166 ILE D O   1 
ATOM   11668 C CB  . ILE D 1 166 ? -36.951 -0.417  10.175  1.00 47.58  ? 166 ILE D CB  1 
ATOM   11669 C CG1 . ILE D 1 166 ? -37.838 0.757   10.203  1.00 55.38  ? 166 ILE D CG1 1 
ATOM   11670 C CG2 . ILE D 1 166 ? -37.053 -1.213  11.462  1.00 53.62  ? 166 ILE D CG2 1 
ATOM   11671 C CD1 . ILE D 1 166 ? -37.164 2.009   10.711  1.00 56.95  ? 166 ILE D CD1 1 
ATOM   11672 N N   . ALA D 1 167 ? -34.439 -2.186  9.476   1.00 34.15  ? 167 ALA D N   1 
ATOM   11673 C CA  . ALA D 1 167 ? -33.652 -3.348  9.890   1.00 37.41  ? 167 ALA D CA  1 
ATOM   11674 C C   . ALA D 1 167 ? -32.136 -3.018  9.909   1.00 35.15  ? 167 ALA D C   1 
ATOM   11675 O O   . ALA D 1 167 ? -31.465 -3.290  10.888  1.00 32.75  ? 167 ALA D O   1 
ATOM   11676 C CB  . ALA D 1 167 ? -33.968 -4.556  9.015   1.00 39.64  ? 167 ALA D CB  1 
ATOM   11677 N N   . PRO D 1 168 ? -31.542 -2.414  8.857   1.00 32.87  ? 168 PRO D N   1 
ATOM   11678 C CA  . PRO D 1 168 ? -30.141 -2.029  8.935   1.00 34.46  ? 168 PRO D CA  1 
ATOM   11679 C C   . PRO D 1 168 ? -29.854 -0.933  9.975   1.00 33.46  ? 168 PRO D C   1 
ATOM   11680 O O   . PRO D 1 168 ? -28.846 -0.996  10.662  1.00 31.87  ? 168 PRO D O   1 
ATOM   11681 C CB  . PRO D 1 168 ? -29.792 -1.594  7.480   1.00 36.22  ? 168 PRO D CB  1 
ATOM   11682 C CG  . PRO D 1 168 ? -31.117 -1.233  6.878   1.00 36.22  ? 168 PRO D CG  1 
ATOM   11683 C CD  . PRO D 1 168 ? -32.133 -2.159  7.543   1.00 33.44  ? 168 PRO D CD  1 
ATOM   11684 N N   . ALA D 1 169 ? -30.755 0.050   10.120  1.00 32.19  ? 169 ALA D N   1 
ATOM   11685 C CA  . ALA D 1 169 ? -30.509 1.161   11.075  1.00 31.91  ? 169 ALA D CA  1 
ATOM   11686 C C   . ALA D 1 169 ? -30.405 0.608   12.491  1.00 30.81  ? 169 ALA D C   1 
ATOM   11687 O O   . ALA D 1 169 ? -29.465 0.904   13.216  1.00 30.41  ? 169 ALA D O   1 
ATOM   11688 C CB  . ALA D 1 169 ? -31.587 2.235   10.977  1.00 29.62  ? 169 ALA D CB  1 
ATOM   11689 N N   . LEU D 1 170 ? -31.325 -0.268  12.833  1.00 30.79  ? 170 LEU D N   1 
ATOM   11690 C CA  . LEU D 1 170 ? -31.380 -0.818  14.160  1.00 30.68  ? 170 LEU D CA  1 
ATOM   11691 C C   . LEU D 1 170 ? -30.162 -1.706  14.398  1.00 35.43  ? 170 LEU D C   1 
ATOM   11692 O O   . LEU D 1 170 ? -29.603 -1.705  15.495  1.00 36.69  ? 170 LEU D O   1 
ATOM   11693 C CB  . LEU D 1 170 ? -32.684 -1.586  14.346  1.00 31.68  ? 170 LEU D CB  1 
ATOM   11694 C CG  . LEU D 1 170 ? -33.939 -0.735  14.540  1.00 32.83  ? 170 LEU D CG  1 
ATOM   11695 C CD1 . LEU D 1 170 ? -35.158 -1.593  14.433  1.00 35.11  ? 170 LEU D CD1 1 
ATOM   11696 C CD2 . LEU D 1 170 ? -33.925 0.002   15.880  1.00 32.46  ? 170 LEU D CD2 1 
ATOM   11697 N N   . ALA D 1 171 ? -29.783 -2.497  13.386  1.00 34.67  ? 171 ALA D N   1 
ATOM   11698 C CA  . ALA D 1 171 ? -28.696 -3.468  13.546  1.00 36.42  ? 171 ALA D CA  1 
ATOM   11699 C C   . ALA D 1 171 ? -27.380 -2.745  13.827  1.00 31.90  ? 171 ALA D C   1 
ATOM   11700 O O   . ALA D 1 171 ? -26.555 -3.244  14.560  1.00 29.91  ? 171 ALA D O   1 
ATOM   11701 C CB  . ALA D 1 171 ? -28.568 -4.368  12.305  1.00 36.33  ? 171 ALA D CB  1 
ATOM   11702 N N   . LEU D 1 172 ? -27.197 -1.584  13.205  1.00 30.88  ? 172 LEU D N   1 
ATOM   11703 C CA  . LEU D 1 172 ? -25.939 -0.860  13.278  1.00 29.79  ? 172 LEU D CA  1 
ATOM   11704 C C   . LEU D 1 172 ? -25.908 0.057   14.507  1.00 34.05  ? 172 LEU D C   1 
ATOM   11705 O O   . LEU D 1 172 ? -25.074 0.966   14.567  1.00 39.00  ? 172 LEU D O   1 
ATOM   11706 C CB  . LEU D 1 172 ? -25.776 -0.067  11.990  1.00 31.24  ? 172 LEU D CB  1 
ATOM   11707 C CG  . LEU D 1 172 ? -25.538 -0.906  10.727  1.00 35.80  ? 172 LEU D CG  1 
ATOM   11708 C CD1 . LEU D 1 172 ? -25.589 -0.110  9.418   1.00 37.88  ? 172 LEU D CD1 1 
ATOM   11709 C CD2 . LEU D 1 172 ? -24.197 -1.572  10.860  1.00 39.13  ? 172 LEU D CD2 1 
ATOM   11710 N N   . GLY D 1 173 ? -26.861 -0.142  15.455  1.00 35.05  ? 173 GLY D N   1 
ATOM   11711 C CA  . GLY D 1 173 ? -26.813 0.515   16.760  1.00 38.70  ? 173 GLY D CA  1 
ATOM   11712 C C   . GLY D 1 173 ? -27.639 1.827   16.851  1.00 40.44  ? 173 GLY D C   1 
ATOM   11713 O O   . GLY D 1 173 ? -27.570 2.520   17.875  1.00 43.51  ? 173 GLY D O   1 
ATOM   11714 N N   . ASN D 1 174 ? -28.442 2.146   15.819  1.00 34.57  ? 174 ASN D N   1 
ATOM   11715 C CA  . ASN D 1 174 ? -29.315 3.321   15.879  1.00 35.20  ? 174 ASN D CA  1 
ATOM   11716 C C   . ASN D 1 174 ? -30.627 2.975   16.586  1.00 38.35  ? 174 ASN D C   1 
ATOM   11717 O O   . ASN D 1 174 ? -30.948 1.800   16.787  1.00 35.97  ? 174 ASN D O   1 
ATOM   11718 C CB  . ASN D 1 174 ? -29.624 3.885   14.505  1.00 33.76  ? 174 ASN D CB  1 
ATOM   11719 C CG  . ASN D 1 174 ? -28.384 4.343   13.793  1.00 34.47  ? 174 ASN D CG  1 
ATOM   11720 O OD1 . ASN D 1 174 ? -27.892 5.454   14.044  1.00 40.21  ? 174 ASN D OD1 1 
ATOM   11721 N ND2 . ASN D 1 174 ? -27.896 3.534   12.875  1.00 33.07  ? 174 ASN D ND2 1 
ATOM   11722 N N   . ALA D 1 175 ? -31.383 4.035   16.935  1.00 37.66  ? 175 ALA D N   1 
ATOM   11723 C CA  . ALA D 1 175 ? -32.807 3.943   17.223  1.00 33.34  ? 175 ALA D CA  1 
ATOM   11724 C C   . ALA D 1 175 ? -33.607 4.535   16.058  1.00 32.13  ? 175 ALA D C   1 
ATOM   11725 O O   . ALA D 1 175 ? -33.086 5.328   15.286  1.00 33.98  ? 175 ALA D O   1 
ATOM   11726 C CB  . ALA D 1 175 ? -33.106 4.665   18.525  1.00 35.55  ? 175 ALA D CB  1 
ATOM   11727 N N   . VAL D 1 176 ? -34.900 4.181   15.979  1.00 32.67  ? 176 VAL D N   1 
ATOM   11728 C CA  . VAL D 1 176 ? -35.746 4.625   14.885  1.00 36.07  ? 176 VAL D CA  1 
ATOM   11729 C C   . VAL D 1 176 ? -37.073 5.147   15.437  1.00 36.22  ? 176 VAL D C   1 
ATOM   11730 O O   . VAL D 1 176 ? -37.624 4.585   16.395  1.00 30.21  ? 176 VAL D O   1 
ATOM   11731 C CB  . VAL D 1 176 ? -35.986 3.498   13.859  1.00 35.15  ? 176 VAL D CB  1 
ATOM   11732 C CG1 . VAL D 1 176 ? -34.693 3.091   13.161  1.00 35.60  ? 176 VAL D CG1 1 
ATOM   11733 C CG2 . VAL D 1 176 ? -36.652 2.290   14.496  1.00 38.26  ? 176 VAL D CG2 1 
ATOM   11734 N N   . VAL D 1 177 ? -37.607 6.183   14.753  1.00 34.01  ? 177 VAL D N   1 
ATOM   11735 C CA  . VAL D 1 177 ? -39.000 6.554   14.850  1.00 37.05  ? 177 VAL D CA  1 
ATOM   11736 C C   . VAL D 1 177 ? -39.589 6.587   13.438  1.00 36.09  ? 177 VAL D C   1 
ATOM   11737 O O   . VAL D 1 177 ? -39.028 7.226   12.547  1.00 30.74  ? 177 VAL D O   1 
ATOM   11738 C CB  . VAL D 1 177 ? -39.169 7.918   15.549  1.00 38.21  ? 177 VAL D CB  1 
ATOM   11739 C CG1 . VAL D 1 177 ? -40.636 8.317   15.641  1.00 35.75  ? 177 VAL D CG1 1 
ATOM   11740 C CG2 . VAL D 1 177 ? -38.533 7.923   16.923  1.00 38.30  ? 177 VAL D CG2 1 
ATOM   11741 N N   . VAL D 1 178 ? -40.762 5.953   13.268  1.00 32.44  ? 178 VAL D N   1 
ATOM   11742 C CA  . VAL D 1 178 ? -41.366 5.790   11.953  1.00 31.53  ? 178 VAL D CA  1 
ATOM   11743 C C   . VAL D 1 178 ? -42.679 6.567   11.875  1.00 31.24  ? 178 VAL D C   1 
ATOM   11744 O O   . VAL D 1 178 ? -43.508 6.492   12.784  1.00 31.22  ? 178 VAL D O   1 
ATOM   11745 C CB  . VAL D 1 178 ? -41.600 4.295   11.670  1.00 30.91  ? 178 VAL D CB  1 
ATOM   11746 C CG1 . VAL D 1 178 ? -42.383 4.088   10.371  1.00 28.37  ? 178 VAL D CG1 1 
ATOM   11747 C CG2 . VAL D 1 178 ? -40.288 3.522   11.651  1.00 30.62  ? 178 VAL D CG2 1 
ATOM   11748 N N   . LYS D 1 179 ? -42.899 7.224   10.730  1.00 32.21  ? 179 LYS D N   1 
ATOM   11749 C CA  . LYS D 1 179 ? -44.160 7.897   10.445  1.00 38.66  ? 179 LYS D CA  1 
ATOM   11750 C C   . LYS D 1 179 ? -44.821 7.258   9.222   1.00 36.26  ? 179 LYS D C   1 
ATOM   11751 O O   . LYS D 1 179 ? -44.458 7.559   8.077   1.00 39.17  ? 179 LYS D O   1 
ATOM   11752 C CB  . LYS D 1 179 ? -43.969 9.408   10.191  1.00 42.72  ? 179 LYS D CB  1 
ATOM   11753 C CG  . LYS D 1 179 ? -45.272 10.197  10.214  1.00 45.92  ? 179 LYS D CG  1 
ATOM   11754 C CD  . LYS D 1 179 ? -45.408 11.249  9.131   1.00 56.12  ? 179 LYS D CD  1 
ATOM   11755 C CE  . LYS D 1 179 ? -44.725 12.534  9.480   1.00 63.76  ? 179 LYS D CE  1 
ATOM   11756 N NZ  . LYS D 1 179 ? -44.480 13.368  8.285   1.00 71.18  ? 179 LYS D NZ  1 
ATOM   11757 N N   . PRO D 1 180 ? -45.814 6.367   9.412   1.00 35.39  ? 180 PRO D N   1 
ATOM   11758 C CA  . PRO D 1 180 ? -46.410 5.660   8.286   1.00 39.94  ? 180 PRO D CA  1 
ATOM   11759 C C   . PRO D 1 180 ? -47.462 6.490   7.584   1.00 39.78  ? 180 PRO D C   1 
ATOM   11760 O O   . PRO D 1 180 ? -47.906 7.507   8.105   1.00 44.05  ? 180 PRO D O   1 
ATOM   11761 C CB  . PRO D 1 180 ? -46.985 4.376   8.905   1.00 39.13  ? 180 PRO D CB  1 
ATOM   11762 C CG  . PRO D 1 180 ? -47.278 4.767   10.332  1.00 38.40  ? 180 PRO D CG  1 
ATOM   11763 C CD  . PRO D 1 180 ? -46.297 5.885   10.705  1.00 35.72  ? 180 PRO D CD  1 
ATOM   11764 N N   . ALA D 1 181 ? -47.802 6.076   6.367   1.00 40.65  ? 181 ALA D N   1 
ATOM   11765 C CA  . ALA D 1 181 ? -48.926 6.660   5.642   1.00 41.41  ? 181 ALA D CA  1 
ATOM   11766 C C   . ALA D 1 181 ? -50.244 6.348   6.369   1.00 39.22  ? 181 ALA D C   1 
ATOM   11767 O O   . ALA D 1 181 ? -50.409 5.272   6.980   1.00 35.22  ? 181 ALA D O   1 
ATOM   11768 C CB  . ALA D 1 181 ? -48.945 6.150   4.220   1.00 37.18  ? 181 ALA D CB  1 
ATOM   11769 N N   . SER D 1 182 ? -51.191 7.266   6.243   1.00 42.07  ? 182 SER D N   1 
ATOM   11770 C CA  . SER D 1 182 ? -52.405 7.244   7.051   1.00 48.15  ? 182 SER D CA  1 
ATOM   11771 C C   . SER D 1 182 ? -53.298 6.064   6.643   1.00 40.70  ? 182 SER D C   1 
ATOM   11772 O O   . SER D 1 182 ? -54.076 5.566   7.445   1.00 39.04  ? 182 SER D O   1 
ATOM   11773 C CB  . SER D 1 182 ? -53.148 8.546   6.937   1.00 54.98  ? 182 SER D CB  1 
ATOM   11774 O OG  . SER D 1 182 ? -54.109 8.476   5.895   1.00 66.93  ? 182 SER D OG  1 
ATOM   11775 N N   . ASP D 1 183 ? -53.144 5.595   5.399   1.00 36.38  ? 183 ASP D N   1 
ATOM   11776 C CA  . ASP D 1 183 ? -53.946 4.498   4.901   1.00 36.03  ? 183 ASP D CA  1 
ATOM   11777 C C   . ASP D 1 183 ? -53.368 3.149   5.322   1.00 36.83  ? 183 ASP D C   1 
ATOM   11778 O O   . ASP D 1 183 ? -54.078 2.138   5.272   1.00 34.93  ? 183 ASP D O   1 
ATOM   11779 C CB  . ASP D 1 183 ? -54.121 4.590   3.405   1.00 44.98  ? 183 ASP D CB  1 
ATOM   11780 C CG  . ASP D 1 183 ? -54.928 5.787   2.957   1.00 47.74  ? 183 ASP D CG  1 
ATOM   11781 O OD1 . ASP D 1 183 ? -56.150 5.790   3.203   1.00 52.55  ? 183 ASP D OD1 1 
ATOM   11782 O OD2 . ASP D 1 183 ? -54.319 6.730   2.458   1.00 56.87  ? 183 ASP D OD2 1 
ATOM   11783 N N   . THR D 1 184 ? -52.068 3.109   5.680   1.00 37.88  ? 184 THR D N   1 
ATOM   11784 C CA  . THR D 1 184 ? -51.404 1.829   5.939   1.00 37.00  ? 184 THR D CA  1 
ATOM   11785 C C   . THR D 1 184 ? -50.569 1.917   7.215   1.00 35.22  ? 184 THR D C   1 
ATOM   11786 O O   . THR D 1 184 ? -49.369 1.625   7.193   1.00 31.02  ? 184 THR D O   1 
ATOM   11787 C CB  . THR D 1 184 ? -50.537 1.421   4.735   1.00 38.96  ? 184 THR D CB  1 
ATOM   11788 O OG1 . THR D 1 184 ? -49.566 2.444   4.533   1.00 37.84  ? 184 THR D OG1 1 
ATOM   11789 C CG2 . THR D 1 184 ? -51.341 1.228   3.457   1.00 39.82  ? 184 THR D CG2 1 
ATOM   11790 N N   . PRO D 1 185 ? -51.177 2.246   8.372   1.00 31.37  ? 185 PRO D N   1 
ATOM   11791 C CA  . PRO D 1 185 ? -50.434 2.296   9.629   1.00 36.99  ? 185 PRO D CA  1 
ATOM   11792 C C   . PRO D 1 185 ? -49.921 0.939   10.142  1.00 33.86  ? 185 PRO D C   1 
ATOM   11793 O O   . PRO D 1 185 ? -48.852 0.873   10.725  1.00 33.00  ? 185 PRO D O   1 
ATOM   11794 C CB  . PRO D 1 185 ? -51.433 2.955   10.611  1.00 35.96  ? 185 PRO D CB  1 
ATOM   11795 C CG  . PRO D 1 185 ? -52.796 2.568   10.045  1.00 35.75  ? 185 PRO D CG  1 
ATOM   11796 C CD  . PRO D 1 185 ? -52.585 2.622   8.526   1.00 34.67  ? 185 PRO D CD  1 
ATOM   11797 N N   . VAL D 1 186 ? -50.662 -0.137  9.904   1.00 31.98  ? 186 VAL D N   1 
ATOM   11798 C CA  . VAL D 1 186 ? -50.274 -1.428  10.450  1.00 33.12  ? 186 VAL D CA  1 
ATOM   11799 C C   . VAL D 1 186 ? -49.028 -1.966  9.703   1.00 35.06  ? 186 VAL D C   1 
ATOM   11800 O O   . VAL D 1 186 ? -47.998 -2.253  10.335  1.00 36.42  ? 186 VAL D O   1 
ATOM   11801 C CB  . VAL D 1 186 ? -51.425 -2.422  10.414  1.00 34.16  ? 186 VAL D CB  1 
ATOM   11802 C CG1 . VAL D 1 186 ? -50.975 -3.818  10.831  1.00 36.78  ? 186 VAL D CG1 1 
ATOM   11803 C CG2 . VAL D 1 186 ? -52.583 -1.963  11.271  1.00 36.95  ? 186 VAL D CG2 1 
ATOM   11804 N N   . CYS D 1 187 ? -49.112 -2.058  8.373   1.00 34.78  ? 187 CYS D N   1 
ATOM   11805 C CA  . CYS D 1 187 ? -47.949 -2.507  7.561   1.00 39.23  ? 187 CYS D CA  1 
ATOM   11806 C C   . CYS D 1 187 ? -46.951 -1.346  7.448   1.00 41.12  ? 187 CYS D C   1 
ATOM   11807 O O   . CYS D 1 187 ? -45.902 -1.534  6.815   1.00 41.93  ? 187 CYS D O   1 
ATOM   11808 C CB  . CYS D 1 187 ? -48.406 -2.980  6.187   1.00 39.74  ? 187 CYS D CB  1 
ATOM   11809 S SG  . CYS D 1 187 ? -49.863 -4.052  6.242   1.00 47.78  ? 187 CYS D SG  1 
ATOM   11810 N N   . GLY D 1 188 ? -47.245 -0.220  8.100   1.00 42.57  ? 188 GLY D N   1 
ATOM   11811 C CA  . GLY D 1 188 ? -46.385 0.978   8.054   1.00 37.26  ? 188 GLY D CA  1 
ATOM   11812 C C   . GLY D 1 188 ? -45.352 0.961   9.157   1.00 36.93  ? 188 GLY D C   1 
ATOM   11813 O O   . GLY D 1 188 ? -44.565 1.919   9.227   1.00 42.80  ? 188 GLY D O   1 
ATOM   11814 N N   . GLY D 1 189 ? -45.331 -0.098  9.970   1.00 33.97  ? 189 GLY D N   1 
ATOM   11815 C CA  . GLY D 1 189 ? -44.386 -0.196  11.098  1.00 33.60  ? 189 GLY D CA  1 
ATOM   11816 C C   . GLY D 1 189 ? -45.035 -0.528  12.423  1.00 31.77  ? 189 GLY D C   1 
ATOM   11817 O O   . GLY D 1 189 ? -44.283 -0.845  13.356  1.00 30.86  ? 189 GLY D O   1 
ATOM   11818 N N   . LEU D 1 190 ? -46.364 -0.516  12.514  1.00 32.29  ? 190 LEU D N   1 
ATOM   11819 C CA  . LEU D 1 190 ? -47.007 -0.989  13.767  1.00 35.73  ? 190 LEU D CA  1 
ATOM   11820 C C   . LEU D 1 190 ? -46.743 -2.498  13.863  1.00 38.05  ? 190 LEU D C   1 
ATOM   11821 O O   . LEU D 1 190 ? -46.361 -2.967  14.952  1.00 37.73  ? 190 LEU D O   1 
ATOM   11822 C CB  . LEU D 1 190 ? -48.504 -0.692  13.774  1.00 33.16  ? 190 LEU D CB  1 
ATOM   11823 C CG  . LEU D 1 190 ? -48.915 0.751   14.078  1.00 34.89  ? 190 LEU D CG  1 
ATOM   11824 C CD1 . LEU D 1 190 ? -50.409 0.922   13.881  1.00 34.90  ? 190 LEU D CD1 1 
ATOM   11825 C CD2 . LEU D 1 190 ? -48.529 1.127   15.490  1.00 34.69  ? 190 LEU D CD2 1 
ATOM   11826 N N   . LEU D 1 191 ? -46.917 -3.216  12.751  1.00 37.50  ? 191 LEU D N   1 
ATOM   11827 C CA  . LEU D 1 191 ? -46.699 -4.664  12.712  1.00 38.12  ? 191 LEU D CA  1 
ATOM   11828 C C   . LEU D 1 191 ? -45.213 -4.958  12.932  1.00 34.10  ? 191 LEU D C   1 
ATOM   11829 O O   . LEU D 1 191 ? -44.872 -5.906  13.634  1.00 29.77  ? 191 LEU D O   1 
ATOM   11830 C CB  . LEU D 1 191 ? -47.192 -5.233  11.376  1.00 39.12  ? 191 LEU D CB  1 
ATOM   11831 C CG  . LEU D 1 191 ? -47.432 -6.735  11.328  1.00 38.58  ? 191 LEU D CG  1 
ATOM   11832 C CD1 . LEU D 1 191 ? -48.557 -7.131  12.270  1.00 42.12  ? 191 LEU D CD1 1 
ATOM   11833 C CD2 . LEU D 1 191 ? -47.737 -7.156  9.936   1.00 39.15  ? 191 LEU D CD2 1 
ATOM   11834 N N   . LEU D 1 192 ? -44.336 -4.134  12.306  1.00 30.76  ? 192 LEU D N   1 
ATOM   11835 C CA  . LEU D 1 192 ? -42.890 -4.337  12.390  1.00 32.34  ? 192 LEU D CA  1 
ATOM   11836 C C   . LEU D 1 192 ? -42.441 -4.133  13.838  1.00 34.15  ? 192 LEU D C   1 
ATOM   11837 O O   . LEU D 1 192 ? -41.591 -4.871  14.337  1.00 30.28  ? 192 LEU D O   1 
ATOM   11838 C CB  . LEU D 1 192 ? -42.139 -3.413  11.422  1.00 29.63  ? 192 LEU D CB  1 
ATOM   11839 C CG  . LEU D 1 192 ? -42.251 -3.778  9.927   1.00 32.84  ? 192 LEU D CG  1 
ATOM   11840 C CD1 . LEU D 1 192 ? -41.663 -2.716  9.040   1.00 31.17  ? 192 LEU D CD1 1 
ATOM   11841 C CD2 . LEU D 1 192 ? -41.586 -5.136  9.619   1.00 34.16  ? 192 LEU D CD2 1 
ATOM   11842 N N   . ALA D 1 193 ? -43.068 -3.157  14.522  1.00 35.63  ? 193 ALA D N   1 
ATOM   11843 C CA  . ALA D 1 193 ? -42.738 -2.854  15.904  1.00 35.58  ? 193 ALA D CA  1 
ATOM   11844 C C   . ALA D 1 193 ? -43.074 -4.047  16.809  1.00 34.15  ? 193 ALA D C   1 
ATOM   11845 O O   . ALA D 1 193 ? -42.304 -4.381  17.685  1.00 33.28  ? 193 ALA D O   1 
ATOM   11846 C CB  . ALA D 1 193 ? -43.453 -1.607  16.337  1.00 34.26  ? 193 ALA D CB  1 
ATOM   11847 N N   . ARG D 1 194 ? -44.222 -4.692  16.559  1.00 36.62  ? 194 ARG D N   1 
ATOM   11848 C CA  . ARG D 1 194 ? -44.630 -5.880  17.317  1.00 39.94  ? 194 ARG D CA  1 
ATOM   11849 C C   . ARG D 1 194 ? -43.658 -7.042  17.099  1.00 38.46  ? 194 ARG D C   1 
ATOM   11850 O O   . ARG D 1 194 ? -43.322 -7.756  18.046  1.00 40.21  ? 194 ARG D O   1 
ATOM   11851 C CB  . ARG D 1 194 ? -46.026 -6.327  16.896  1.00 43.20  ? 194 ARG D CB  1 
ATOM   11852 C CG  . ARG D 1 194 ? -47.114 -5.396  17.390  1.00 45.93  ? 194 ARG D CG  1 
ATOM   11853 C CD  . ARG D 1 194 ? -47.245 -5.445  18.889  1.00 45.66  ? 194 ARG D CD  1 
ATOM   11854 N NE  . ARG D 1 194 ? -48.514 -4.828  19.276  1.00 64.05  ? 194 ARG D NE  1 
ATOM   11855 C CZ  . ARG D 1 194 ? -49.640 -5.488  19.557  1.00 62.16  ? 194 ARG D CZ  1 
ATOM   11856 N NH1 . ARG D 1 194 ? -49.621 -6.813  19.720  1.00 51.10  ? 194 ARG D NH1 1 
ATOM   11857 N NH2 . ARG D 1 194 ? -50.758 -4.804  19.723  1.00 64.07  ? 194 ARG D NH2 1 
ATOM   11858 N N   . ILE D 1 195 ? -43.244 -7.235  15.843  1.00 36.04  ? 195 ILE D N   1 
ATOM   11859 C CA  . ILE D 1 195 ? -42.292 -8.272  15.482  1.00 35.11  ? 195 ILE D CA  1 
ATOM   11860 C C   . ILE D 1 195 ? -40.952 -8.045  16.216  1.00 33.69  ? 195 ILE D C   1 
ATOM   11861 O O   . ILE D 1 195 ? -40.409 -8.970  16.808  1.00 30.14  ? 195 ILE D O   1 
ATOM   11862 C CB  . ILE D 1 195 ? -42.128 -8.340  13.954  1.00 33.57  ? 195 ILE D CB  1 
ATOM   11863 C CG1 . ILE D 1 195 ? -43.357 -8.920  13.315  1.00 32.83  ? 195 ILE D CG1 1 
ATOM   11864 C CG2 . ILE D 1 195 ? -40.877 -9.111  13.552  1.00 34.09  ? 195 ILE D CG2 1 
ATOM   11865 C CD1 . ILE D 1 195 ? -43.472 -8.638  11.841  1.00 33.85  ? 195 ILE D CD1 1 
ATOM   11866 N N   . PHE D 1 196 ? -40.439 -6.815  16.207  1.00 34.48  ? 196 PHE D N   1 
ATOM   11867 C CA  . PHE D 1 196 ? -39.127 -6.551  16.808  1.00 35.25  ? 196 PHE D CA  1 
ATOM   11868 C C   . PHE D 1 196 ? -39.212 -6.703  18.328  1.00 37.65  ? 196 PHE D C   1 
ATOM   11869 O O   . PHE D 1 196 ? -38.250 -7.129  18.962  1.00 36.51  ? 196 PHE D O   1 
ATOM   11870 C CB  . PHE D 1 196 ? -38.595 -5.183  16.419  1.00 35.51  ? 196 PHE D CB  1 
ATOM   11871 C CG  . PHE D 1 196 ? -37.735 -5.176  15.168  1.00 36.23  ? 196 PHE D CG  1 
ATOM   11872 C CD1 . PHE D 1 196 ? -36.436 -5.660  15.194  1.00 40.35  ? 196 PHE D CD1 1 
ATOM   11873 C CD2 . PHE D 1 196 ? -38.206 -4.648  13.978  1.00 41.21  ? 196 PHE D CD2 1 
ATOM   11874 C CE1 . PHE D 1 196 ? -35.642 -5.626  14.053  1.00 36.55  ? 196 PHE D CE1 1 
ATOM   11875 C CE2 . PHE D 1 196 ? -37.403 -4.615  12.848  1.00 37.52  ? 196 PHE D CE2 1 
ATOM   11876 C CZ  . PHE D 1 196 ? -36.125 -5.098  12.897  1.00 35.72  ? 196 PHE D CZ  1 
ATOM   11877 N N   . GLU D 1 197 ? -40.383 -6.392  18.899  1.00 36.88  ? 197 GLU D N   1 
ATOM   11878 C CA  . GLU D 1 197 ? -40.592 -6.545  20.331  1.00 39.76  ? 197 GLU D CA  1 
ATOM   11879 C C   . GLU D 1 197 ? -40.545 -8.036  20.712  1.00 38.61  ? 197 GLU D C   1 
ATOM   11880 O O   . GLU D 1 197 ? -39.834 -8.418  21.619  1.00 38.57  ? 197 GLU D O   1 
ATOM   11881 C CB  . GLU D 1 197 ? -41.901 -5.900  20.773  1.00 45.80  ? 197 GLU D CB  1 
ATOM   11882 C CG  . GLU D 1 197 ? -41.997 -5.726  22.283  1.00 48.94  ? 197 GLU D CG  1 
ATOM   11883 C CD  . GLU D 1 197 ? -43.401 -5.676  22.786  1.00 61.67  ? 197 GLU D CD  1 
ATOM   11884 O OE1 . GLU D 1 197 ? -44.148 -6.627  22.491  1.00 65.91  ? 197 GLU D OE1 1 
ATOM   11885 O OE2 . GLU D 1 197 ? -43.752 -4.702  23.473  1.00 74.47  ? 197 GLU D OE2 1 
ATOM   11886 N N   . GLU D 1 198 ? -41.270 -8.871  19.989  1.00 38.75  ? 198 GLU D N   1 
ATOM   11887 C CA  . GLU D 1 198 ? -41.234 -10.307 20.248  1.00 41.65  ? 198 GLU D CA  1 
ATOM   11888 C C   . GLU D 1 198 ? -39.808 -10.844 20.039  1.00 40.31  ? 198 GLU D C   1 
ATOM   11889 O O   . GLU D 1 198 ? -39.435 -11.824 20.661  1.00 40.58  ? 198 GLU D O   1 
ATOM   11890 C CB  . GLU D 1 198 ? -42.264 -11.014 19.360  1.00 46.34  ? 198 GLU D CB  1 
ATOM   11891 C CG  . GLU D 1 198 ? -42.256 -12.534 19.476  1.00 46.26  ? 198 GLU D CG  1 
ATOM   11892 C CD  . GLU D 1 198 ? -43.353 -13.221 18.645  1.00 53.48  ? 198 GLU D CD  1 
ATOM   11893 O OE1 . GLU D 1 198 ? -43.974 -12.551 17.783  1.00 50.61  ? 198 GLU D OE1 1 
ATOM   11894 O OE2 . GLU D 1 198 ? -43.600 -14.433 18.870  1.00 57.93  ? 198 GLU D OE2 1 
ATOM   11895 N N   . ALA D 1 199 ? -39.017 -10.168 19.168  1.00 40.44  ? 199 ALA D N   1 
ATOM   11896 C CA  . ALA D 1 199 ? -37.638 -10.580 18.856  1.00 43.95  ? 199 ALA D CA  1 
ATOM   11897 C C   . ALA D 1 199 ? -36.622 -10.052 19.904  1.00 44.34  ? 199 ALA D C   1 
ATOM   11898 O O   . ALA D 1 199 ? -35.413 -10.287 19.776  1.00 43.30  ? 199 ALA D O   1 
ATOM   11899 C CB  . ALA D 1 199 ? -37.253 -10.104 17.448  1.00 42.56  ? 199 ALA D CB  1 
ATOM   11900 N N   . GLY D 1 200 ? -37.098 -9.300  20.887  1.00 38.26  ? 200 GLY D N   1 
ATOM   11901 C CA  . GLY D 1 200 ? -36.292 -8.975  22.050  1.00 41.34  ? 200 GLY D CA  1 
ATOM   11902 C C   . GLY D 1 200 ? -35.616 -7.603  21.936  1.00 45.92  ? 200 GLY D C   1 
ATOM   11903 O O   . GLY D 1 200 ? -34.664 -7.323  22.670  1.00 47.60  ? 200 GLY D O   1 
ATOM   11904 N N   . LEU D 1 201 ? -36.115 -6.738  21.031  1.00 45.03  ? 201 LEU D N   1 
ATOM   11905 C CA  . LEU D 1 201 ? -35.606 -5.372  20.935  1.00 40.08  ? 201 LEU D CA  1 
ATOM   11906 C C   . LEU D 1 201 ? -35.979 -4.606  22.204  1.00 40.02  ? 201 LEU D C   1 
ATOM   11907 O O   . LEU D 1 201 ? -37.130 -4.529  22.561  1.00 42.83  ? 201 LEU D O   1 
ATOM   11908 C CB  . LEU D 1 201 ? -36.154 -4.678  19.704  1.00 37.31  ? 201 LEU D CB  1 
ATOM   11909 C CG  . LEU D 1 201 ? -35.668 -3.248  19.486  1.00 37.92  ? 201 LEU D CG  1 
ATOM   11910 C CD1 . LEU D 1 201 ? -34.318 -3.242  18.808  1.00 39.37  ? 201 LEU D CD1 1 
ATOM   11911 C CD2 . LEU D 1 201 ? -36.685 -2.447  18.686  1.00 38.27  ? 201 LEU D CD2 1 
ATOM   11912 N N   . PRO D 1 202 ? -35.014 -4.000  22.910  1.00 43.90  ? 202 PRO D N   1 
ATOM   11913 C CA  . PRO D 1 202 ? -35.336 -3.148  24.065  1.00 46.85  ? 202 PRO D CA  1 
ATOM   11914 C C   . PRO D 1 202 ? -36.360 -2.035  23.780  1.00 46.25  ? 202 PRO D C   1 
ATOM   11915 O O   . PRO D 1 202 ? -36.387 -1.467  22.697  1.00 44.92  ? 202 PRO D O   1 
ATOM   11916 C CB  . PRO D 1 202 ? -33.941 -2.575  24.448  1.00 46.63  ? 202 PRO D CB  1 
ATOM   11917 C CG  . PRO D 1 202 ? -32.967 -3.652  23.976  1.00 45.90  ? 202 PRO D CG  1 
ATOM   11918 C CD  . PRO D 1 202 ? -33.562 -4.131  22.670  1.00 44.90  ? 202 PRO D CD  1 
ATOM   11919 N N   . ALA D 1 203 ? -37.153 -1.703  24.807  1.00 43.80  ? 203 ALA D N   1 
ATOM   11920 C CA  . ALA D 1 203 ? -38.252 -0.764  24.685  1.00 46.29  ? 203 ALA D CA  1 
ATOM   11921 C C   . ALA D 1 203 ? -37.722 0.654   24.453  1.00 45.89  ? 203 ALA D C   1 
ATOM   11922 O O   . ALA D 1 203 ? -36.727 1.051   25.043  1.00 48.84  ? 203 ALA D O   1 
ATOM   11923 C CB  . ALA D 1 203 ? -39.113 -0.837  25.937  1.00 44.98  ? 203 ALA D CB  1 
ATOM   11924 N N   . GLY D 1 204 ? -38.402 1.408   23.582  1.00 43.94  ? 204 GLY D N   1 
ATOM   11925 C CA  . GLY D 1 204 ? -38.041 2.800   23.326  1.00 43.56  ? 204 GLY D CA  1 
ATOM   11926 C C   . GLY D 1 204 ? -37.206 2.980   22.039  1.00 42.02  ? 204 GLY D C   1 
ATOM   11927 O O   . GLY D 1 204 ? -37.146 4.091   21.491  1.00 34.58  ? 204 GLY D O   1 
ATOM   11928 N N   . LEU D 1 205 ? -36.576 1.881   21.546  1.00 44.01  ? 205 LEU D N   1 
ATOM   11929 C CA  . LEU D 1 205 ? -35.707 1.957   20.361  1.00 46.53  ? 205 LEU D CA  1 
ATOM   11930 C C   . LEU D 1 205 ? -36.535 2.138   19.085  1.00 41.22  ? 205 LEU D C   1 
ATOM   11931 O O   . LEU D 1 205 ? -36.042 2.695   18.116  1.00 43.61  ? 205 LEU D O   1 
ATOM   11932 C CB  . LEU D 1 205 ? -34.820 0.724   20.257  1.00 49.00  ? 205 LEU D CB  1 
ATOM   11933 C CG  . LEU D 1 205 ? -33.731 0.600   21.318  1.00 49.50  ? 205 LEU D CG  1 
ATOM   11934 C CD1 . LEU D 1 205 ? -33.127 -0.785  21.282  1.00 50.98  ? 205 LEU D CD1 1 
ATOM   11935 C CD2 . LEU D 1 205 ? -32.663 1.669   21.141  1.00 50.24  ? 205 LEU D CD2 1 
ATOM   11936 N N   . PHE D 1 206 ? -37.791 1.661   19.099  1.00 39.54  ? 206 PHE D N   1 
ATOM   11937 C CA  . PHE D 1 206 ? -38.662 1.721   17.928  1.00 39.04  ? 206 PHE D CA  1 
ATOM   11938 C C   . PHE D 1 206 ? -40.024 2.329   18.324  1.00 38.46  ? 206 PHE D C   1 
ATOM   11939 O O   . PHE D 1 206 ? -40.830 1.678   18.988  1.00 34.71  ? 206 PHE D O   1 
ATOM   11940 C CB  . PHE D 1 206 ? -38.812 0.296   17.337  1.00 39.35  ? 206 PHE D CB  1 
ATOM   11941 C CG  . PHE D 1 206 ? -39.517 0.219   15.989  1.00 39.88  ? 206 PHE D CG  1 
ATOM   11942 C CD1 . PHE D 1 206 ? -40.094 1.351   15.402  1.00 37.98  ? 206 PHE D CD1 1 
ATOM   11943 C CD2 . PHE D 1 206 ? -39.630 -0.991  15.316  1.00 45.28  ? 206 PHE D CD2 1 
ATOM   11944 C CE1 . PHE D 1 206 ? -40.717 1.271   14.171  1.00 39.19  ? 206 PHE D CE1 1 
ATOM   11945 C CE2 . PHE D 1 206 ? -40.263 -1.058  14.078  1.00 41.30  ? 206 PHE D CE2 1 
ATOM   11946 C CZ  . PHE D 1 206 ? -40.794 0.072   13.510  1.00 38.78  ? 206 PHE D CZ  1 
ATOM   11947 N N   . SER D 1 207 ? -40.306 3.557   17.825  1.00 40.61  ? 207 SER D N   1 
ATOM   11948 C CA  . SER D 1 207 ? -41.613 4.180   17.999  1.00 39.16  ? 207 SER D CA  1 
ATOM   11949 C C   . SER D 1 207 ? -42.270 4.441   16.643  1.00 41.14  ? 207 SER D C   1 
ATOM   11950 O O   . SER D 1 207 ? -41.587 4.710   15.651  1.00 41.15  ? 207 SER D O   1 
ATOM   11951 C CB  . SER D 1 207 ? -41.507 5.450   18.798  1.00 42.23  ? 207 SER D CB  1 
ATOM   11952 O OG  . SER D 1 207 ? -41.466 5.157   20.187  1.00 41.24  ? 207 SER D OG  1 
ATOM   11953 N N   . VAL D 1 208 ? -43.617 4.395   16.642  1.00 37.30  ? 208 VAL D N   1 
ATOM   11954 C CA  . VAL D 1 208 ? -44.412 4.671   15.471  1.00 36.53  ? 208 VAL D CA  1 
ATOM   11955 C C   . VAL D 1 208 ? -45.424 5.762   15.825  1.00 37.38  ? 208 VAL D C   1 
ATOM   11956 O O   . VAL D 1 208 ? -46.152 5.629   16.787  1.00 35.20  ? 208 VAL D O   1 
ATOM   11957 C CB  . VAL D 1 208 ? -45.134 3.404   14.981  1.00 38.31  ? 208 VAL D CB  1 
ATOM   11958 C CG1 . VAL D 1 208 ? -45.968 3.686   13.739  1.00 39.43  ? 208 VAL D CG1 1 
ATOM   11959 C CG2 . VAL D 1 208 ? -44.174 2.248   14.738  1.00 37.71  ? 208 VAL D CG2 1 
ATOM   11960 N N   . VAL D 1 209 ? -45.479 6.819   15.004  1.00 36.60  ? 209 VAL D N   1 
ATOM   11961 C CA  . VAL D 1 209 ? -46.295 7.978   15.293  1.00 37.62  ? 209 VAL D CA  1 
ATOM   11962 C C   . VAL D 1 209 ? -47.347 8.116   14.217  1.00 39.50  ? 209 VAL D C   1 
ATOM   11963 O O   . VAL D 1 209 ? -47.026 8.469   13.072  1.00 37.80  ? 209 VAL D O   1 
ATOM   11964 C CB  . VAL D 1 209 ? -45.445 9.253   15.380  1.00 47.84  ? 209 VAL D CB  1 
ATOM   11965 C CG1 . VAL D 1 209 ? -46.294 10.485  15.691  1.00 51.39  ? 209 VAL D CG1 1 
ATOM   11966 C CG2 . VAL D 1 209 ? -44.319 9.114   16.393  1.00 53.00  ? 209 VAL D CG2 1 
ATOM   11967 N N   . VAL D 1 210 ? -48.611 7.903   14.606  1.00 42.90  ? 210 VAL D N   1 
ATOM   11968 C CA  . VAL D 1 210 ? -49.731 7.969   13.674  1.00 44.79  ? 210 VAL D CA  1 
ATOM   11969 C C   . VAL D 1 210 ? -50.586 9.149   14.060  1.00 46.44  ? 210 VAL D C   1 
ATOM   11970 O O   . VAL D 1 210 ? -51.224 9.123   15.105  1.00 48.99  ? 210 VAL D O   1 
ATOM   11971 C CB  . VAL D 1 210 ? -50.581 6.691   13.652  1.00 41.39  ? 210 VAL D CB  1 
ATOM   11972 C CG1 . VAL D 1 210 ? -51.554 6.706   12.495  1.00 45.19  ? 210 VAL D CG1 1 
ATOM   11973 C CG2 . VAL D 1 210 ? -49.729 5.440   13.615  1.00 44.91  ? 210 VAL D CG2 1 
ATOM   11974 N N   . GLY D 1 211 ? -50.581 10.176  13.222  1.00 48.33  ? 211 GLY D N   1 
ATOM   11975 C CA  . GLY D 1 211 ? -51.156 11.448  13.594  1.00 57.20  ? 211 GLY D CA  1 
ATOM   11976 C C   . GLY D 1 211 ? -51.610 12.239  12.376  1.00 61.79  ? 211 GLY D C   1 
ATOM   11977 O O   . GLY D 1 211 ? -51.271 11.902  11.245  1.00 51.38  ? 211 GLY D O   1 
ATOM   11978 N N   . PRO D 1 212 ? -52.413 13.310  12.578  1.00 83.30  ? 212 PRO D N   1 
ATOM   11979 C CA  . PRO D 1 212 ? -52.834 14.177  11.476  1.00 89.28  ? 212 PRO D CA  1 
ATOM   11980 C C   . PRO D 1 212 ? -51.654 14.924  10.864  1.00 91.82  ? 212 PRO D C   1 
ATOM   11981 O O   . PRO D 1 212 ? -50.923 15.617  11.570  1.00 89.79  ? 212 PRO D O   1 
ATOM   11982 C CB  . PRO D 1 212 ? -53.860 15.134  12.145  1.00 87.17  ? 212 PRO D CB  1 
ATOM   11983 C CG  . PRO D 1 212 ? -53.461 15.136  13.616  1.00 85.29  ? 212 PRO D CG  1 
ATOM   11984 C CD  . PRO D 1 212 ? -52.963 13.727  13.879  1.00 85.27  ? 212 PRO D CD  1 
ATOM   11985 N N   . GLY D 1 213 ? -51.496 14.785  9.539   1.00 96.85  ? 213 GLY D N   1 
ATOM   11986 C CA  . GLY D 1 213 ? -50.353 15.342  8.823   1.00 108.64 ? 213 GLY D CA  1 
ATOM   11987 C C   . GLY D 1 213 ? -50.273 16.870  8.954   1.00 121.48 ? 213 GLY D C   1 
ATOM   11988 O O   . GLY D 1 213 ? -49.202 17.451  8.778   1.00 130.57 ? 213 GLY D O   1 
ATOM   11989 N N   . SER D 1 214 ? -51.421 17.514  9.240   1.00 125.58 ? 214 SER D N   1 
ATOM   11990 C CA  . SER D 1 214 ? -51.467 18.957  9.464   1.00 119.04 ? 214 SER D CA  1 
ATOM   11991 C C   . SER D 1 214 ? -50.626 19.333  10.693  1.00 104.44 ? 214 SER D C   1 
ATOM   11992 O O   . SER D 1 214 ? -49.774 20.209  10.618  1.00 95.78  ? 214 SER D O   1 
ATOM   11993 C CB  . SER D 1 214 ? -52.895 19.440  9.605   1.00 117.18 ? 214 SER D CB  1 
ATOM   11994 O OG  . SER D 1 214 ? -53.609 18.649  10.544  1.00 117.72 ? 214 SER D OG  1 
ATOM   11995 N N   . GLU D 1 215 ? -50.858 18.628  11.805  1.00 94.10  ? 215 GLU D N   1 
ATOM   11996 C CA  . GLU D 1 215 ? -50.177 18.896  13.067  1.00 93.18  ? 215 GLU D CA  1 
ATOM   11997 C C   . GLU D 1 215 ? -48.717 18.368  13.015  1.00 98.49  ? 215 GLU D C   1 
ATOM   11998 O O   . GLU D 1 215 ? -47.765 19.155  13.069  1.00 94.58  ? 215 GLU D O   1 
ATOM   11999 C CB  . GLU D 1 215 ? -51.053 18.305  14.178  1.00 92.08  ? 215 GLU D CB  1 
ATOM   12000 C CG  . GLU D 1 215 ? -50.298 17.864  15.427  1.00 96.18  ? 215 GLU D CG  1 
ATOM   12001 C CD  . GLU D 1 215 ? -51.197 17.134  16.416  1.00 93.77  ? 215 GLU D CD  1 
ATOM   12002 O OE1 . GLU D 1 215 ? -51.646 17.790  17.380  1.00 91.20  ? 215 GLU D OE1 1 
ATOM   12003 O OE2 . GLU D 1 215 ? -51.472 15.923  16.208  1.00 90.50  ? 215 GLU D OE2 1 
ATOM   12004 N N   . ILE D 1 216 ? -48.551 17.036  12.875  1.00 87.85  ? 216 ILE D N   1 
ATOM   12005 C CA  . ILE D 1 216 ? -47.267 16.384  13.140  1.00 71.21  ? 216 ILE D CA  1 
ATOM   12006 C C   . ILE D 1 216 ? -46.395 16.333  11.871  1.00 63.81  ? 216 ILE D C   1 
ATOM   12007 O O   . ILE D 1 216 ? -45.248 15.952  11.945  1.00 64.14  ? 216 ILE D O   1 
ATOM   12008 C CB  . ILE D 1 216 ? -47.462 14.971  13.743  1.00 77.33  ? 216 ILE D CB  1 
ATOM   12009 C CG1 . ILE D 1 216 ? -48.303 14.076  12.864  1.00 80.04  ? 216 ILE D CG1 1 
ATOM   12010 C CG2 . ILE D 1 216 ? -48.024 15.049  15.165  1.00 89.88  ? 216 ILE D CG2 1 
ATOM   12011 C CD1 . ILE D 1 216 ? -47.521 13.351  11.791  1.00 87.48  ? 216 ILE D CD1 1 
ATOM   12012 N N   . GLY D 1 217 ? -46.939 16.716  10.714  1.00 67.94  ? 217 GLY D N   1 
ATOM   12013 C CA  . GLY D 1 217 ? -46.269 16.475  9.428   1.00 65.93  ? 217 GLY D CA  1 
ATOM   12014 C C   . GLY D 1 217 ? -44.844 17.076  9.361   1.00 65.01  ? 217 GLY D C   1 
ATOM   12015 O O   . GLY D 1 217 ? -43.851 16.348  9.301   1.00 62.54  ? 217 GLY D O   1 
ATOM   12016 N N   . ASP D 1 218 ? -44.764 18.407  9.283   1.00 61.38  ? 218 ASP D N   1 
ATOM   12017 C CA  . ASP D 1 218 ? -43.497 19.093  9.118   1.00 55.81  ? 218 ASP D CA  1 
ATOM   12018 C C   . ASP D 1 218 ? -42.608 18.897  10.346  1.00 53.23  ? 218 ASP D C   1 
ATOM   12019 O O   . ASP D 1 218 ? -41.387 18.862  10.222  1.00 50.90  ? 218 ASP D O   1 
ATOM   12020 C CB  . ASP D 1 218 ? -43.714 20.564  8.857   1.00 61.05  ? 218 ASP D CB  1 
ATOM   12021 C CG  . ASP D 1 218 ? -44.393 20.879  7.544   1.00 67.11  ? 218 ASP D CG  1 
ATOM   12022 O OD1 . ASP D 1 218 ? -44.680 19.909  6.784   1.00 65.31  ? 218 ASP D OD1 1 
ATOM   12023 O OD2 . ASP D 1 218 ? -44.635 22.082  7.288   1.00 67.80  ? 218 ASP D OD2 1 
ATOM   12024 N N   . ALA D 1 219 ? -43.231 18.807  11.534  1.00 46.91  ? 219 ALA D N   1 
ATOM   12025 C CA  . ALA D 1 219 ? -42.493 18.732  12.785  1.00 50.64  ? 219 ALA D CA  1 
ATOM   12026 C C   . ALA D 1 219 ? -41.643 17.459  12.846  1.00 54.81  ? 219 ALA D C   1 
ATOM   12027 O O   . ALA D 1 219 ? -40.618 17.446  13.527  1.00 56.23  ? 219 ALA D O   1 
ATOM   12028 C CB  . ALA D 1 219 ? -43.445 18.798  13.950  1.00 57.21  ? 219 ALA D CB  1 
ATOM   12029 N N   . PHE D 1 220 ? -42.097 16.375  12.153  1.00 51.40  ? 220 PHE D N   1 
ATOM   12030 C CA  . PHE D 1 220 ? -41.362 15.110  12.122  1.00 45.47  ? 220 PHE D CA  1 
ATOM   12031 C C   . PHE D 1 220 ? -39.982 15.343  11.515  1.00 43.53  ? 220 PHE D C   1 
ATOM   12032 O O   . PHE D 1 220 ? -38.982 14.851  12.040  1.00 44.59  ? 220 PHE D O   1 
ATOM   12033 C CB  . PHE D 1 220 ? -42.125 14.031  11.338  1.00 48.28  ? 220 PHE D CB  1 
ATOM   12034 C CG  . PHE D 1 220 ? -41.565 12.627  11.519  1.00 42.45  ? 220 PHE D CG  1 
ATOM   12035 C CD1 . PHE D 1 220 ? -41.929 11.849  12.616  1.00 40.70  ? 220 PHE D CD1 1 
ATOM   12036 C CD2 . PHE D 1 220 ? -40.648 12.102  10.617  1.00 39.46  ? 220 PHE D CD2 1 
ATOM   12037 C CE1 . PHE D 1 220 ? -41.390 10.586  12.796  1.00 42.65  ? 220 PHE D CE1 1 
ATOM   12038 C CE2 . PHE D 1 220 ? -40.117 10.827  10.802  1.00 38.13  ? 220 PHE D CE2 1 
ATOM   12039 C CZ  . PHE D 1 220 ? -40.491 10.076  11.878  1.00 39.91  ? 220 PHE D CZ  1 
ATOM   12040 N N   . VAL D 1 221 ? -39.944 16.110  10.416  1.00 38.02  ? 221 VAL D N   1 
ATOM   12041 C CA  . VAL D 1 221 ? -38.712 16.381  9.707   1.00 42.03  ? 221 VAL D CA  1 
ATOM   12042 C C   . VAL D 1 221 ? -37.888 17.440  10.453  1.00 50.19  ? 221 VAL D C   1 
ATOM   12043 O O   . VAL D 1 221 ? -36.672 17.346  10.487  1.00 50.24  ? 221 VAL D O   1 
ATOM   12044 C CB  . VAL D 1 221 ? -39.023 16.829  8.280   1.00 45.50  ? 221 VAL D CB  1 
ATOM   12045 C CG1 . VAL D 1 221 ? -37.762 16.971  7.445   1.00 48.13  ? 221 VAL D CG1 1 
ATOM   12046 C CG2 . VAL D 1 221 ? -40.006 15.891  7.611   1.00 48.89  ? 221 VAL D CG2 1 
ATOM   12047 N N   . GLU D 1 222 ? -38.561 18.470  11.023  1.00 53.89  ? 222 GLU D N   1 
ATOM   12048 C CA  . GLU D 1 222 ? -37.868 19.651  11.554  1.00 53.35  ? 222 GLU D CA  1 
ATOM   12049 C C   . GLU D 1 222 ? -37.222 19.346  12.905  1.00 51.88  ? 222 GLU D C   1 
ATOM   12050 O O   . GLU D 1 222 ? -36.346 20.068  13.340  1.00 58.59  ? 222 GLU D O   1 
ATOM   12051 C CB  . GLU D 1 222 ? -38.812 20.830  11.706  1.00 58.17  ? 222 GLU D CB  1 
ATOM   12052 C CG  . GLU D 1 222 ? -39.039 21.581  10.402  1.00 66.94  ? 222 GLU D CG  1 
ATOM   12053 C CD  . GLU D 1 222 ? -40.274 22.451  10.404  1.00 74.30  ? 222 GLU D CD  1 
ATOM   12054 O OE1 . GLU D 1 222 ? -41.121 22.278  11.308  1.00 76.50  ? 222 GLU D OE1 1 
ATOM   12055 O OE2 . GLU D 1 222 ? -40.386 23.310  9.506   1.00 85.23  ? 222 GLU D OE2 1 
ATOM   12056 N N   . HIS D 1 223 ? -37.643 18.262  13.548  1.00 50.62  ? 223 HIS D N   1 
ATOM   12057 C CA  . HIS D 1 223 ? -37.264 18.007  14.932  1.00 52.04  ? 223 HIS D CA  1 
ATOM   12058 C C   . HIS D 1 223 ? -35.740 17.944  15.052  1.00 55.06  ? 223 HIS D C   1 
ATOM   12059 O O   . HIS D 1 223 ? -35.063 17.422  14.175  1.00 56.37  ? 223 HIS D O   1 
ATOM   12060 C CB  . HIS D 1 223 ? -37.897 16.713  15.422  1.00 48.28  ? 223 HIS D CB  1 
ATOM   12061 C CG  . HIS D 1 223 ? -38.027 16.625  16.883  1.00 47.21  ? 223 HIS D CG  1 
ATOM   12062 N ND1 . HIS D 1 223 ? -37.009 16.196  17.704  1.00 49.83  ? 223 HIS D ND1 1 
ATOM   12063 C CD2 . HIS D 1 223 ? -39.086 16.846  17.683  1.00 49.02  ? 223 HIS D CD2 1 
ATOM   12064 C CE1 . HIS D 1 223 ? -37.444 16.181  18.962  1.00 49.60  ? 223 HIS D CE1 1 
ATOM   12065 N NE2 . HIS D 1 223 ? -38.702 16.563  18.969  1.00 46.88  ? 223 HIS D NE2 1 
ATOM   12066 N N   . PRO D 1 224 ? -35.155 18.483  16.137  1.00 62.41  ? 224 PRO D N   1 
ATOM   12067 C CA  . PRO D 1 224 ? -33.704 18.479  16.293  1.00 60.44  ? 224 PRO D CA  1 
ATOM   12068 C C   . PRO D 1 224 ? -33.058 17.119  16.606  1.00 55.45  ? 224 PRO D C   1 
ATOM   12069 O O   . PRO D 1 224 ? -31.888 16.924  16.312  1.00 58.24  ? 224 PRO D O   1 
ATOM   12070 C CB  . PRO D 1 224 ? -33.514 19.504  17.450  1.00 61.55  ? 224 PRO D CB  1 
ATOM   12071 C CG  . PRO D 1 224 ? -34.786 19.377  18.263  1.00 58.06  ? 224 PRO D CG  1 
ATOM   12072 C CD  . PRO D 1 224 ? -35.849 19.226  17.210  1.00 62.99  ? 224 PRO D CD  1 
ATOM   12073 N N   . VAL D 1 225 ? -33.821 16.191  17.211  1.00 51.06  ? 225 VAL D N   1 
ATOM   12074 C CA  . VAL D 1 225 ? -33.257 14.914  17.678  1.00 48.82  ? 225 VAL D CA  1 
ATOM   12075 C C   . VAL D 1 225 ? -32.694 14.081  16.500  1.00 46.81  ? 225 VAL D C   1 
ATOM   12076 O O   . VAL D 1 225 ? -31.563 13.619  16.572  1.00 45.64  ? 225 VAL D O   1 
ATOM   12077 C CB  . VAL D 1 225 ? -34.265 14.094  18.495  1.00 54.27  ? 225 VAL D CB  1 
ATOM   12078 C CG1 . VAL D 1 225 ? -33.860 12.623  18.583  1.00 52.97  ? 225 VAL D CG1 1 
ATOM   12079 C CG2 . VAL D 1 225 ? -34.462 14.685  19.898  1.00 52.80  ? 225 VAL D CG2 1 
ATOM   12080 N N   . PRO D 1 226 ? -33.466 13.786  15.412  1.00 47.01  ? 226 PRO D N   1 
ATOM   12081 C CA  . PRO D 1 226 ? -32.987 12.840  14.392  1.00 48.74  ? 226 PRO D CA  1 
ATOM   12082 C C   . PRO D 1 226 ? -31.722 13.328  13.677  1.00 47.76  ? 226 PRO D C   1 
ATOM   12083 O O   . PRO D 1 226 ? -31.679 14.440  13.181  1.00 51.63  ? 226 PRO D O   1 
ATOM   12084 C CB  . PRO D 1 226 ? -34.194 12.726  13.441  1.00 46.82  ? 226 PRO D CB  1 
ATOM   12085 C CG  . PRO D 1 226 ? -34.923 14.052  13.618  1.00 48.15  ? 226 PRO D CG  1 
ATOM   12086 C CD  . PRO D 1 226 ? -34.790 14.346  15.093  1.00 45.77  ? 226 PRO D CD  1 
ATOM   12087 N N   . GLY D 1 227 ? -30.711 12.471  13.619  1.00 44.67  ? 227 GLY D N   1 
ATOM   12088 C CA  . GLY D 1 227 ? -29.546 12.704  12.768  1.00 45.93  ? 227 GLY D CA  1 
ATOM   12089 C C   . GLY D 1 227 ? -29.871 12.572  11.249  1.00 51.44  ? 227 GLY D C   1 
ATOM   12090 O O   . GLY D 1 227 ? -29.211 13.198  10.430  1.00 54.12  ? 227 GLY D O   1 
ATOM   12091 N N   . LEU D 1 228 ? -30.839 11.701  10.884  1.00 44.77  ? 228 LEU D N   1 
ATOM   12092 C CA  . LEU D 1 228 ? -31.115 11.400  9.480   1.00 43.56  ? 228 LEU D CA  1 
ATOM   12093 C C   . LEU D 1 228 ? -32.617 11.160  9.294   1.00 43.43  ? 228 LEU D C   1 
ATOM   12094 O O   . LEU D 1 228 ? -33.278 10.573  10.164  1.00 43.08  ? 228 LEU D O   1 
ATOM   12095 C CB  . LEU D 1 228 ? -30.277 10.188  9.051   1.00 43.05  ? 228 LEU D CB  1 
ATOM   12096 C CG  . LEU D 1 228 ? -30.645 9.516   7.721   1.00 46.33  ? 228 LEU D CG  1 
ATOM   12097 C CD1 . LEU D 1 228 ? -30.201 10.349  6.517   1.00 49.07  ? 228 LEU D CD1 1 
ATOM   12098 C CD2 . LEU D 1 228 ? -30.037 8.113   7.651   1.00 46.46  ? 228 LEU D CD2 1 
ATOM   12099 N N   . VAL D 1 229 ? -33.145 11.627  8.152   1.00 40.94  ? 229 VAL D N   1 
ATOM   12100 C CA  . VAL D 1 229 ? -34.525 11.362  7.766   1.00 45.52  ? 229 VAL D CA  1 
ATOM   12101 C C   . VAL D 1 229 ? -34.527 10.680  6.402   1.00 42.42  ? 229 VAL D C   1 
ATOM   12102 O O   . VAL D 1 229 ? -33.906 11.169  5.468   1.00 40.67  ? 229 VAL D O   1 
ATOM   12103 C CB  . VAL D 1 229 ? -35.390 12.631  7.730   1.00 50.93  ? 229 VAL D CB  1 
ATOM   12104 C CG1 . VAL D 1 229 ? -36.833 12.310  7.350   1.00 50.53  ? 229 VAL D CG1 1 
ATOM   12105 C CG2 . VAL D 1 229 ? -35.343 13.382  9.052   1.00 53.81  ? 229 VAL D CG2 1 
ATOM   12106 N N   . THR D 1 230 ? -35.246 9.547   6.309   1.00 38.44  ? 230 THR D N   1 
ATOM   12107 C CA  . THR D 1 230 ? -35.255 8.729   5.111   1.00 40.18  ? 230 THR D CA  1 
ATOM   12108 C C   . THR D 1 230 ? -36.673 8.680   4.582   1.00 43.45  ? 230 THR D C   1 
ATOM   12109 O O   . THR D 1 230 ? -37.623 8.563   5.356   1.00 48.41  ? 230 THR D O   1 
ATOM   12110 C CB  . THR D 1 230 ? -34.712 7.313   5.405   1.00 44.07  ? 230 THR D CB  1 
ATOM   12111 O OG1 . THR D 1 230 ? -35.633 6.606   6.242   1.00 45.98  ? 230 THR D OG1 1 
ATOM   12112 C CG2 . THR D 1 230 ? -33.377 7.336   6.116   1.00 44.40  ? 230 THR D CG2 1 
ATOM   12113 N N   . PHE D 1 231 ? -36.795 8.751   3.252   1.00 45.76  ? 231 PHE D N   1 
ATOM   12114 C CA  . PHE D 1 231 ? -38.061 8.597   2.573   1.00 42.31  ? 231 PHE D CA  1 
ATOM   12115 C C   . PHE D 1 231 ? -37.814 7.917   1.242   1.00 46.90  ? 231 PHE D C   1 
ATOM   12116 O O   . PHE D 1 231 ? -36.978 8.355   0.478   1.00 42.19  ? 231 PHE D O   1 
ATOM   12117 C CB  . PHE D 1 231 ? -38.743 9.948   2.338   1.00 46.60  ? 231 PHE D CB  1 
ATOM   12118 C CG  . PHE D 1 231 ? -39.958 9.871   1.427   1.00 50.80  ? 231 PHE D CG  1 
ATOM   12119 C CD1 . PHE D 1 231 ? -41.120 9.225   1.841   1.00 57.52  ? 231 PHE D CD1 1 
ATOM   12120 C CD2 . PHE D 1 231 ? -39.929 10.414  0.148   1.00 53.25  ? 231 PHE D CD2 1 
ATOM   12121 C CE1 . PHE D 1 231 ? -42.218 9.128   0.993   1.00 63.73  ? 231 PHE D CE1 1 
ATOM   12122 C CE2 . PHE D 1 231 ? -41.031 10.323  -0.691  1.00 53.11  ? 231 PHE D CE2 1 
ATOM   12123 C CZ  . PHE D 1 231 ? -42.169 9.680   -0.271  1.00 61.06  ? 231 PHE D CZ  1 
ATOM   12124 N N   . THR D 1 232 ? -38.582 6.860   0.972   1.00 54.55  ? 232 THR D N   1 
ATOM   12125 C CA  . THR D 1 232 ? -38.660 6.261   -0.356  1.00 58.38  ? 232 THR D CA  1 
ATOM   12126 C C   . THR D 1 232 ? -40.101 6.375   -0.857  1.00 56.77  ? 232 THR D C   1 
ATOM   12127 O O   . THR D 1 232 ? -41.004 5.888   -0.199  1.00 64.64  ? 232 THR D O   1 
ATOM   12128 C CB  . THR D 1 232 ? -38.226 4.792   -0.262  1.00 60.33  ? 232 THR D CB  1 
ATOM   12129 O OG1 . THR D 1 232 ? -36.864 4.760   0.154   1.00 60.25  ? 232 THR D OG1 1 
ATOM   12130 C CG2 . THR D 1 232 ? -38.367 4.061   -1.585  1.00 62.08  ? 232 THR D CG2 1 
ATOM   12131 N N   . GLY D 1 233 ? -40.321 7.019   -2.014  1.00 56.60  ? 233 GLY D N   1 
ATOM   12132 C CA  . GLY D 1 233 ? -41.666 7.015   -2.600  1.00 59.68  ? 233 GLY D CA  1 
ATOM   12133 C C   . GLY D 1 233 ? -41.924 8.162   -3.594  1.00 62.37  ? 233 GLY D C   1 
ATOM   12134 O O   . GLY D 1 233 ? -41.152 8.395   -4.516  1.00 65.40  ? 233 GLY D O   1 
ATOM   12135 N N   . SER D 1 234 ? -43.078 8.807   -3.422  1.00 63.60  ? 234 SER D N   1 
ATOM   12136 C CA  . SER D 1 234 ? -43.618 9.753   -4.380  1.00 69.69  ? 234 SER D CA  1 
ATOM   12137 C C   . SER D 1 234 ? -42.694 10.976  -4.525  1.00 68.66  ? 234 SER D C   1 
ATOM   12138 O O   . SER D 1 234 ? -42.099 11.431  -3.556  1.00 71.48  ? 234 SER D O   1 
ATOM   12139 C CB  . SER D 1 234 ? -45.014 10.167  -3.959  1.00 69.96  ? 234 SER D CB  1 
ATOM   12140 O OG  . SER D 1 234 ? -45.484 11.230  -4.766  1.00 75.04  ? 234 SER D OG  1 
ATOM   12141 N N   . THR D 1 235 ? -42.645 11.542  -5.741  1.00 71.78  ? 235 THR D N   1 
ATOM   12142 C CA  . THR D 1 235 ? -41.787 12.694  -6.027  1.00 73.04  ? 235 THR D CA  1 
ATOM   12143 C C   . THR D 1 235 ? -42.305 13.944  -5.292  1.00 75.19  ? 235 THR D C   1 
ATOM   12144 O O   . THR D 1 235 ? -41.540 14.602  -4.605  1.00 76.38  ? 235 THR D O   1 
ATOM   12145 C CB  . THR D 1 235 ? -41.677 12.935  -7.535  1.00 71.18  ? 235 THR D CB  1 
ATOM   12146 O OG1 . THR D 1 235 ? -40.987 11.810  -8.073  1.00 76.17  ? 235 THR D OG1 1 
ATOM   12147 C CG2 . THR D 1 235 ? -40.887 14.188  -7.865  1.00 73.26  ? 235 THR D CG2 1 
ATOM   12148 N N   . PRO D 1 236 ? -43.591 14.349  -5.432  1.00 79.82  ? 236 PRO D N   1 
ATOM   12149 C CA  . PRO D 1 236 ? -44.070 15.557  -4.740  1.00 77.71  ? 236 PRO D CA  1 
ATOM   12150 C C   . PRO D 1 236 ? -43.877 15.471  -3.219  1.00 71.86  ? 236 PRO D C   1 
ATOM   12151 O O   . PRO D 1 236 ? -43.490 16.449  -2.584  1.00 63.14  ? 236 PRO D O   1 
ATOM   12152 C CB  . PRO D 1 236 ? -45.566 15.667  -5.145  1.00 75.55  ? 236 PRO D CB  1 
ATOM   12153 C CG  . PRO D 1 236 ? -45.932 14.248  -5.624  1.00 75.40  ? 236 PRO D CG  1 
ATOM   12154 C CD  . PRO D 1 236 ? -44.640 13.689  -6.235  1.00 73.41  ? 236 PRO D CD  1 
ATOM   12155 N N   . VAL D 1 237 ? -44.150 14.287  -2.650  1.00 68.68  ? 237 VAL D N   1 
ATOM   12156 C CA  . VAL D 1 237 ? -44.014 14.075  -1.216  1.00 69.47  ? 237 VAL D CA  1 
ATOM   12157 C C   . VAL D 1 237 ? -42.537 14.245  -0.836  1.00 74.17  ? 237 VAL D C   1 
ATOM   12158 O O   . VAL D 1 237 ? -42.211 14.964  0.105   1.00 79.02  ? 237 VAL D O   1 
ATOM   12159 C CB  . VAL D 1 237 ? -44.553 12.694  -0.772  1.00 65.82  ? 237 VAL D CB  1 
ATOM   12160 C CG1 . VAL D 1 237 ? -44.181 12.375  0.676   1.00 61.13  ? 237 VAL D CG1 1 
ATOM   12161 C CG2 . VAL D 1 237 ? -46.067 12.575  -0.973  1.00 67.97  ? 237 VAL D CG2 1 
ATOM   12162 N N   . GLY D 1 238 ? -41.654 13.576  -1.583  1.00 64.83  ? 238 GLY D N   1 
ATOM   12163 C CA  . GLY D 1 238 ? -40.229 13.655  -1.333  1.00 65.92  ? 238 GLY D CA  1 
ATOM   12164 C C   . GLY D 1 238 ? -39.724 15.087  -1.457  1.00 66.61  ? 238 GLY D C   1 
ATOM   12165 O O   . GLY D 1 238 ? -38.874 15.510  -0.688  1.00 67.42  ? 238 GLY D O   1 
ATOM   12166 N N   . ARG D 1 239 ? -40.232 15.807  -2.460  1.00 67.40  ? 239 ARG D N   1 
ATOM   12167 C CA  . ARG D 1 239 ? -39.801 17.166  -2.737  1.00 73.40  ? 239 ARG D CA  1 
ATOM   12168 C C   . ARG D 1 239 ? -40.121 18.065  -1.547  1.00 67.84  ? 239 ARG D C   1 
ATOM   12169 O O   . ARG D 1 239 ? -39.303 18.869  -1.142  1.00 60.09  ? 239 ARG D O   1 
ATOM   12170 C CB  . ARG D 1 239 ? -40.485 17.670  -4.010  1.00 87.07  ? 239 ARG D CB  1 
ATOM   12171 C CG  . ARG D 1 239 ? -39.935 17.062  -5.297  1.00 100.62 ? 239 ARG D CG  1 
ATOM   12172 C CD  . ARG D 1 239 ? -38.483 17.451  -5.574  1.00 101.30 ? 239 ARG D CD  1 
ATOM   12173 N NE  . ARG D 1 239 ? -38.319 18.907  -5.645  1.00 109.38 ? 239 ARG D NE  1 
ATOM   12174 C CZ  . ARG D 1 239 ? -38.947 19.703  -6.506  1.00 109.90 ? 239 ARG D CZ  1 
ATOM   12175 N NH1 . ARG D 1 239 ? -39.661 19.183  -7.488  1.00 108.81 ? 239 ARG D NH1 1 
ATOM   12176 N NH2 . ARG D 1 239 ? -38.844 21.013  -6.393  1.00 117.23 ? 239 ARG D NH2 1 
ATOM   12177 N N   . ASN D 1 240 ? -41.325 17.913  -1.005  1.00 67.72  ? 240 ASN D N   1 
ATOM   12178 C CA  . ASN D 1 240 ? -41.745 18.655  0.172   1.00 69.50  ? 240 ASN D CA  1 
ATOM   12179 C C   . ASN D 1 240 ? -40.799 18.350  1.342   1.00 72.35  ? 240 ASN D C   1 
ATOM   12180 O O   . ASN D 1 240 ? -40.340 19.253  2.010   1.00 73.23  ? 240 ASN D O   1 
ATOM   12181 C CB  . ASN D 1 240 ? -43.196 18.353  0.522   1.00 69.34  ? 240 ASN D CB  1 
ATOM   12182 C CG  . ASN D 1 240 ? -43.739 19.316  1.533   1.00 73.61  ? 240 ASN D CG  1 
ATOM   12183 O OD1 . ASN D 1 240 ? -44.009 18.931  2.676   1.00 69.75  ? 240 ASN D OD1 1 
ATOM   12184 N ND2 . ASN D 1 240 ? -43.871 20.578  1.147   1.00 79.05  ? 240 ASN D ND2 1 
ATOM   12185 N N   . ILE D 1 241 ? -40.508 17.057  1.566   1.00 66.98  ? 241 ILE D N   1 
ATOM   12186 C CA  . ILE D 1 241 ? -39.614 16.635  2.643   1.00 58.27  ? 241 ILE D CA  1 
ATOM   12187 C C   . ILE D 1 241 ? -38.256 17.340  2.481   1.00 56.38  ? 241 ILE D C   1 
ATOM   12188 O O   . ILE D 1 241 ? -37.641 17.745  3.475   1.00 51.09  ? 241 ILE D O   1 
ATOM   12189 C CB  . ILE D 1 241 ? -39.484 15.091  2.677   1.00 52.77  ? 241 ILE D CB  1 
ATOM   12190 C CG1 . ILE D 1 241 ? -40.794 14.451  3.053   1.00 55.18  ? 241 ILE D CG1 1 
ATOM   12191 C CG2 . ILE D 1 241 ? -38.357 14.632  3.614   1.00 48.07  ? 241 ILE D CG2 1 
ATOM   12192 C CD1 . ILE D 1 241 ? -40.920 13.005  2.627   1.00 52.44  ? 241 ILE D CD1 1 
ATOM   12193 N N   . GLY D 1 242 ? -37.839 17.538  1.223   1.00 55.93  ? 242 GLY D N   1 
ATOM   12194 C CA  . GLY D 1 242 ? -36.601 18.247  0.897   1.00 57.03  ? 242 GLY D CA  1 
ATOM   12195 C C   . GLY D 1 242 ? -36.574 19.676  1.452   1.00 57.54  ? 242 GLY D C   1 
ATOM   12196 O O   . GLY D 1 242 ? -35.601 20.061  2.100   1.00 65.10  ? 242 GLY D O   1 
ATOM   12197 N N   . ARG D 1 243 ? -37.637 20.453  1.177   1.00 61.10  ? 243 ARG D N   1 
ATOM   12198 C CA  . ARG D 1 243 ? -37.701 21.857  1.581   1.00 70.28  ? 243 ARG D CA  1 
ATOM   12199 C C   . ARG D 1 243 ? -37.809 21.981  3.096   1.00 68.86  ? 243 ARG D C   1 
ATOM   12200 O O   . ARG D 1 243 ? -37.154 22.833  3.693   1.00 67.63  ? 243 ARG D O   1 
ATOM   12201 C CB  . ARG D 1 243 ? -38.888 22.546  0.934   1.00 79.91  ? 243 ARG D CB  1 
ATOM   12202 C CG  . ARG D 1 243 ? -38.788 22.499  -0.568  1.00 95.36  ? 243 ARG D CG  1 
ATOM   12203 C CD  . ARG D 1 243 ? -40.122 22.254  -1.211  1.00 100.72 ? 243 ARG D CD  1 
ATOM   12204 N NE  . ARG D 1 243 ? -40.208 22.936  -2.513  1.00 116.17 ? 243 ARG D NE  1 
ATOM   12205 C CZ  . ARG D 1 243 ? -40.445 22.370  -3.720  1.00 125.26 ? 243 ARG D CZ  1 
ATOM   12206 N NH1 . ARG D 1 243 ? -40.859 21.121  -3.819  1.00 133.28 ? 243 ARG D NH1 1 
ATOM   12207 N NH2 . ARG D 1 243 ? -40.305 23.091  -4.821  1.00 122.60 ? 243 ARG D NH2 1 
ATOM   12208 N N   . ILE D 1 244 ? -38.649 21.142  3.716   1.00 67.23  ? 244 ILE D N   1 
ATOM   12209 C CA  . ILE D 1 244 ? -38.849 21.226  5.152   1.00 62.72  ? 244 ILE D CA  1 
ATOM   12210 C C   . ILE D 1 244 ? -37.493 21.028  5.829   1.00 62.61  ? 244 ILE D C   1 
ATOM   12211 O O   . ILE D 1 244 ? -37.172 21.732  6.779   1.00 67.31  ? 244 ILE D O   1 
ATOM   12212 C CB  . ILE D 1 244 ? -39.899 20.217  5.666   1.00 62.08  ? 244 ILE D CB  1 
ATOM   12213 C CG1 . ILE D 1 244 ? -41.154 20.103  4.726   1.00 62.06  ? 244 ILE D CG1 1 
ATOM   12214 C CG2 . ILE D 1 244 ? -40.295 20.557  7.098   1.00 58.19  ? 244 ILE D CG2 1 
ATOM   12215 C CD1 . ILE D 1 244 ? -42.156 21.245  4.848   1.00 64.16  ? 244 ILE D CD1 1 
ATOM   12216 N N   . ALA D 1 245 ? -36.680 20.105  5.273   1.00 66.11  ? 245 ALA D N   1 
ATOM   12217 C CA  . ALA D 1 245 ? -35.344 19.816  5.793   1.00 69.27  ? 245 ALA D CA  1 
ATOM   12218 C C   . ALA D 1 245 ? -34.461 21.053  5.693   1.00 70.25  ? 245 ALA D C   1 
ATOM   12219 O O   . ALA D 1 245 ? -33.868 21.464  6.675   1.00 85.54  ? 245 ALA D O   1 
ATOM   12220 C CB  . ALA D 1 245 ? -34.724 18.642  5.048   1.00 69.90  ? 245 ALA D CB  1 
ATOM   12221 N N   . SER D 1 246 ? -34.383 21.636  4.497   1.00 71.61  ? 246 SER D N   1 
ATOM   12222 C CA  . SER D 1 246 ? -33.519 22.780  4.256   1.00 75.77  ? 246 SER D CA  1 
ATOM   12223 C C   . SER D 1 246 ? -34.104 24.041  4.910   1.00 82.78  ? 246 SER D C   1 
ATOM   12224 O O   . SER D 1 246 ? -33.365 24.867  5.441   1.00 85.51  ? 246 SER D O   1 
ATOM   12225 C CB  . SER D 1 246 ? -33.309 22.980  2.796   1.00 82.88  ? 246 SER D CB  1 
ATOM   12226 O OG  . SER D 1 246 ? -34.537 23.258  2.135   1.00 75.47  ? 246 SER D OG  1 
ATOM   12227 N N   . GLY D 1 247 ? -35.439 24.166  4.872   1.00 94.97  ? 247 GLY D N   1 
ATOM   12228 C CA  . GLY D 1 247 ? -36.130 25.354  5.356   1.00 92.79  ? 247 GLY D CA  1 
ATOM   12229 C C   . GLY D 1 247 ? -36.027 25.503  6.879   1.00 99.28  ? 247 GLY D C   1 
ATOM   12230 O O   . GLY D 1 247 ? -36.049 26.614  7.395   1.00 102.58 ? 247 GLY D O   1 
ATOM   12231 N N   . GLY D 1 248 ? -35.916 24.374  7.589   1.00 106.46 ? 248 GLY D N   1 
ATOM   12232 C CA  . GLY D 1 248 ? -36.014 24.373  9.045   1.00 113.74 ? 248 GLY D CA  1 
ATOM   12233 C C   . GLY D 1 248 ? -34.821 25.079  9.699   1.00 111.92 ? 248 GLY D C   1 
ATOM   12234 O O   . GLY D 1 248 ? -33.767 25.239  9.078   1.00 109.81 ? 248 GLY D O   1 
ATOM   12235 N N   . ALA D 1 249 ? -35.007 25.478  10.969  1.00 110.92 ? 249 ALA D N   1 
ATOM   12236 C CA  . ALA D 1 249 ? -33.940 26.059  11.782  1.00 107.94 ? 249 ALA D CA  1 
ATOM   12237 C C   . ALA D 1 249 ? -32.732 25.117  11.836  1.00 100.63 ? 249 ALA D C   1 
ATOM   12238 O O   . ALA D 1 249 ? -31.601 25.552  11.707  1.00 94.34  ? 249 ALA D O   1 
ATOM   12239 C CB  . ALA D 1 249 ? -34.459 26.364  13.173  1.00 100.77 ? 249 ALA D CB  1 
ATOM   12240 N N   . HIS D 1 250 ? -32.991 23.829  12.059  1.00 100.49 ? 250 HIS D N   1 
ATOM   12241 C CA  . HIS D 1 250 ? -31.940 22.821  12.047  1.00 101.26 ? 250 HIS D CA  1 
ATOM   12242 C C   . HIS D 1 250 ? -31.772 22.308  10.618  1.00 106.49 ? 250 HIS D C   1 
ATOM   12243 O O   . HIS D 1 250 ? -32.755 22.155  9.893   1.00 109.22 ? 250 HIS D O   1 
ATOM   12244 C CB  . HIS D 1 250 ? -32.271 21.676  13.015  1.00 98.28  ? 250 HIS D CB  1 
ATOM   12245 C CG  . HIS D 1 250 ? -32.697 22.130  14.373  1.00 93.48  ? 250 HIS D CG  1 
ATOM   12246 N ND1 . HIS D 1 250 ? -34.015 22.376  14.702  1.00 92.45  ? 250 HIS D ND1 1 
ATOM   12247 C CD2 . HIS D 1 250 ? -31.987 22.385  15.477  1.00 95.46  ? 250 HIS D CD2 1 
ATOM   12248 C CE1 . HIS D 1 250 ? -34.086 22.766  15.964  1.00 96.48  ? 250 HIS D CE1 1 
ATOM   12249 N NE2 . HIS D 1 250 ? -32.867 22.779  16.455  1.00 99.59  ? 250 HIS D NE2 1 
ATOM   12250 N N   . LEU D 1 251 ? -30.530 22.010  10.230  1.00 99.40  ? 251 LEU D N   1 
ATOM   12251 C CA  . LEU D 1 251 ? -30.291 21.385  8.942   1.00 94.53  ? 251 LEU D CA  1 
ATOM   12252 C C   . LEU D 1 251 ? -30.057 19.904  9.120   1.00 83.86  ? 251 LEU D C   1 
ATOM   12253 O O   . LEU D 1 251 ? -29.201 19.488  9.888   1.00 77.48  ? 251 LEU D O   1 
ATOM   12254 C CB  . LEU D 1 251 ? -29.169 22.055  8.178   1.00 91.07  ? 251 LEU D CB  1 
ATOM   12255 C CG  . LEU D 1 251 ? -29.662 22.967  7.065   1.00 105.01 ? 251 LEU D CG  1 
ATOM   12256 C CD1 . LEU D 1 251 ? -30.024 22.175  5.806   1.00 99.35  ? 251 LEU D CD1 1 
ATOM   12257 C CD2 . LEU D 1 251 ? -30.885 23.734  7.581   1.00 113.70 ? 251 LEU D CD2 1 
ATOM   12258 N N   . LYS D 1 252 ? -30.863 19.122  8.405   1.00 81.54  ? 252 LYS D N   1 
ATOM   12259 C CA  . LYS D 1 252 ? -30.927 17.691  8.601   1.00 82.27  ? 252 LYS D CA  1 
ATOM   12260 C C   . LYS D 1 252 ? -30.494 17.005  7.325   1.00 72.60  ? 252 LYS D C   1 
ATOM   12261 O O   . LYS D 1 252 ? -30.916 17.399  6.236   1.00 78.91  ? 252 LYS D O   1 
ATOM   12262 C CB  . LYS D 1 252 ? -32.351 17.259  8.959   1.00 80.70  ? 252 LYS D CB  1 
ATOM   12263 C CG  . LYS D 1 252 ? -33.054 18.154  9.955   1.00 84.13  ? 252 LYS D CG  1 
ATOM   12264 C CD  . LYS D 1 252 ? -33.625 17.398  11.146  1.00 80.40  ? 252 LYS D CD  1 
ATOM   12265 C CE  . LYS D 1 252 ? -32.576 17.011  12.130  1.00 81.56  ? 252 LYS D CE  1 
ATOM   12266 N NZ  . LYS D 1 252 ? -31.940 18.184  12.752  1.00 94.03  ? 252 LYS D NZ  1 
ATOM   12267 N N   . HIS D 1 253 ? -29.680 15.959  7.475   1.00 67.35  ? 253 HIS D N   1 
ATOM   12268 C CA  . HIS D 1 253 ? -29.376 15.068  6.376   1.00 68.89  ? 253 HIS D CA  1 
ATOM   12269 C C   . HIS D 1 253 ? -30.636 14.270  6.058   1.00 57.43  ? 253 HIS D C   1 
ATOM   12270 O O   . HIS D 1 253 ? -31.312 13.792  6.961   1.00 51.18  ? 253 HIS D O   1 
ATOM   12271 C CB  . HIS D 1 253 ? -28.166 14.185  6.711   1.00 80.26  ? 253 HIS D CB  1 
ATOM   12272 C CG  . HIS D 1 253 ? -26.986 14.952  7.243   1.00 97.17  ? 253 HIS D CG  1 
ATOM   12273 N ND1 . HIS D 1 253 ? -25.786 15.057  6.569   1.00 98.90  ? 253 HIS D ND1 1 
ATOM   12274 C CD2 . HIS D 1 253 ? -26.819 15.630  8.399   1.00 97.38  ? 253 HIS D CD2 1 
ATOM   12275 C CE1 . HIS D 1 253 ? -24.940 15.789  7.287   1.00 98.29  ? 253 HIS D CE1 1 
ATOM   12276 N NE2 . HIS D 1 253 ? -25.546 16.143  8.402   1.00 97.19  ? 253 HIS D NE2 1 
ATOM   12277 N N   . VAL D 1 254 ? -30.975 14.200  4.776   1.00 59.19  ? 254 VAL D N   1 
ATOM   12278 C CA  . VAL D 1 254 ? -32.129 13.453  4.330   1.00 63.05  ? 254 VAL D CA  1 
ATOM   12279 C C   . VAL D 1 254 ? -31.681 12.525  3.207   1.00 64.38  ? 254 VAL D C   1 
ATOM   12280 O O   . VAL D 1 254 ? -30.917 12.933  2.334   1.00 64.42  ? 254 VAL D O   1 
ATOM   12281 C CB  . VAL D 1 254 ? -33.292 14.369  3.878   1.00 63.60  ? 254 VAL D CB  1 
ATOM   12282 C CG1 . VAL D 1 254 ? -33.674 15.365  4.955   1.00 73.33  ? 254 VAL D CG1 1 
ATOM   12283 C CG2 . VAL D 1 254 ? -32.983 15.093  2.585   1.00 66.66  ? 254 VAL D CG2 1 
ATOM   12284 N N   . ALA D 1 255 ? -32.166 11.278  3.257   1.00 58.32  ? 255 ALA D N   1 
ATOM   12285 C CA  . ALA D 1 255 ? -31.940 10.302  2.208   1.00 54.01  ? 255 ALA D CA  1 
ATOM   12286 C C   . ALA D 1 255 ? -33.247 10.066  1.431   1.00 52.16  ? 255 ALA D C   1 
ATOM   12287 O O   . ALA D 1 255 ? -34.187 9.468   1.952   1.00 47.17  ? 255 ALA D O   1 
ATOM   12288 C CB  . ALA D 1 255 ? -31.413 9.026   2.824   1.00 54.52  ? 255 ALA D CB  1 
ATOM   12289 N N   . LEU D 1 256 ? -33.281 10.551  0.181   1.00 52.30  ? 256 LEU D N   1 
ATOM   12290 C CA  . LEU D 1 256 ? -34.489 10.545  -0.634  1.00 50.25  ? 256 LEU D CA  1 
ATOM   12291 C C   . LEU D 1 256 ? -34.279 9.653   -1.847  1.00 48.74  ? 256 LEU D C   1 
ATOM   12292 O O   . LEU D 1 256 ? -33.387 9.896   -2.648  1.00 52.48  ? 256 LEU D O   1 
ATOM   12293 C CB  . LEU D 1 256 ? -34.826 11.973  -1.059  1.00 48.37  ? 256 LEU D CB  1 
ATOM   12294 C CG  . LEU D 1 256 ? -35.076 12.960  0.083   1.00 54.73  ? 256 LEU D CG  1 
ATOM   12295 C CD1 . LEU D 1 256 ? -35.146 14.396  -0.435  1.00 55.02  ? 256 LEU D CD1 1 
ATOM   12296 C CD2 . LEU D 1 256 ? -36.334 12.611  0.849   1.00 51.88  ? 256 LEU D CD2 1 
ATOM   12297 N N   . GLU D 1 257 ? -35.102 8.610   -1.956  1.00 54.94  ? 257 GLU D N   1 
ATOM   12298 C CA  . GLU D 1 257 ? -35.197 7.814   -3.173  1.00 60.74  ? 257 GLU D CA  1 
ATOM   12299 C C   . GLU D 1 257 ? -36.559 8.046   -3.800  1.00 51.39  ? 257 GLU D C   1 
ATOM   12300 O O   . GLU D 1 257 ? -37.570 7.613   -3.263  1.00 59.19  ? 257 GLU D O   1 
ATOM   12301 C CB  . GLU D 1 257 ? -34.964 6.325   -2.911  1.00 64.48  ? 257 GLU D CB  1 
ATOM   12302 C CG  . GLU D 1 257 ? -33.596 5.845   -3.386  1.00 77.60  ? 257 GLU D CG  1 
ATOM   12303 C CD  . GLU D 1 257 ? -33.425 4.357   -3.355  1.00 96.32  ? 257 GLU D CD  1 
ATOM   12304 O OE1 . GLU D 1 257 ? -34.344 3.685   -2.829  1.00 98.56  ? 257 GLU D OE1 1 
ATOM   12305 O OE2 . GLU D 1 257 ? -32.391 3.860   -3.876  1.00 109.85 ? 257 GLU D OE2 1 
ATOM   12306 N N   . LEU D 1 258 ? -36.566 8.757   -4.924  1.00 51.12  ? 258 LEU D N   1 
ATOM   12307 C CA  . LEU D 1 258 ? -37.794 9.232   -5.526  1.00 64.69  ? 258 LEU D CA  1 
ATOM   12308 C C   . LEU D 1 258 ? -38.136 8.363   -6.730  1.00 71.29  ? 258 LEU D C   1 
ATOM   12309 O O   . LEU D 1 258 ? -37.301 8.166   -7.614  1.00 71.73  ? 258 LEU D O   1 
ATOM   12310 C CB  . LEU D 1 258 ? -37.651 10.704  -5.920  1.00 72.90  ? 258 LEU D CB  1 
ATOM   12311 C CG  . LEU D 1 258 ? -38.121 11.718  -4.874  1.00 80.12  ? 258 LEU D CG  1 
ATOM   12312 C CD1 . LEU D 1 258 ? -37.276 11.627  -3.619  1.00 78.29  ? 258 LEU D CD1 1 
ATOM   12313 C CD2 . LEU D 1 258 ? -38.116 13.140  -5.444  1.00 83.69  ? 258 LEU D CD2 1 
ATOM   12314 N N   . GLY D 1 259 ? -39.390 7.867   -6.757  1.00 76.28  ? 259 GLY D N   1 
ATOM   12315 C CA  . GLY D 1 259 ? -39.893 7.071   -7.866  1.00 81.22  ? 259 GLY D CA  1 
ATOM   12316 C C   . GLY D 1 259 ? -39.967 7.901   -9.142  1.00 88.10  ? 259 GLY D C   1 
ATOM   12317 O O   . GLY D 1 259 ? -40.084 9.127   -9.091  1.00 96.29  ? 259 GLY D O   1 
ATOM   12318 N N   . GLY D 1 260 ? -39.863 7.227   -10.283 1.00 90.11  ? 260 GLY D N   1 
ATOM   12319 C CA  . GLY D 1 260 ? -39.877 7.910   -11.562 1.00 87.47  ? 260 GLY D CA  1 
ATOM   12320 C C   . GLY D 1 260 ? -40.571 7.087   -12.637 1.00 76.89  ? 260 GLY D C   1 
ATOM   12321 O O   . GLY D 1 260 ? -40.880 5.917   -12.435 1.00 83.14  ? 260 GLY D O   1 
ATOM   12322 N N   . ASN D 1 261 ? -40.786 7.715   -13.787 1.00 64.32  ? 261 ASN D N   1 
ATOM   12323 C CA  . ASN D 1 261 ? -41.188 7.007   -14.984 1.00 52.65  ? 261 ASN D CA  1 
ATOM   12324 C C   . ASN D 1 261 ? -39.974 6.234   -15.520 1.00 45.67  ? 261 ASN D C   1 
ATOM   12325 O O   . ASN D 1 261 ? -39.025 6.835   -16.000 1.00 49.19  ? 261 ASN D O   1 
ATOM   12326 C CB  . ASN D 1 261 ? -41.789 7.968   -16.006 1.00 46.62  ? 261 ASN D CB  1 
ATOM   12327 C CG  . ASN D 1 261 ? -42.682 7.258   -16.994 1.00 50.30  ? 261 ASN D CG  1 
ATOM   12328 O OD1 . ASN D 1 261 ? -42.230 6.335   -17.683 1.00 45.36  ? 261 ASN D OD1 1 
ATOM   12329 N ND2 . ASN D 1 261 ? -43.956 7.646   -17.057 1.00 51.37  ? 261 ASN D ND2 1 
ATOM   12330 N N   . SER D 1 262 ? -40.026 4.896   -15.411 1.00 42.10  ? 262 SER D N   1 
ATOM   12331 C CA  . SER D 1 262 ? -38.907 4.023   -15.765 1.00 38.05  ? 262 SER D CA  1 
ATOM   12332 C C   . SER D 1 262 ? -39.165 3.363   -17.114 1.00 37.61  ? 262 SER D C   1 
ATOM   12333 O O   . SER D 1 262 ? -40.241 2.797   -17.331 1.00 40.18  ? 262 SER D O   1 
ATOM   12334 C CB  . SER D 1 262 ? -38.669 2.989   -14.705 1.00 41.50  ? 262 SER D CB  1 
ATOM   12335 O OG  . SER D 1 262 ? -37.907 3.535   -13.626 1.00 45.86  ? 262 SER D OG  1 
ATOM   12336 N N   . PRO D 1 263 ? -38.213 3.481   -18.092 1.00 35.11  ? 263 PRO D N   1 
ATOM   12337 C CA  . PRO D 1 263 ? -38.444 3.008   -19.457 1.00 35.04  ? 263 PRO D CA  1 
ATOM   12338 C C   . PRO D 1 263 ? -38.092 1.554   -19.697 1.00 30.05  ? 263 PRO D C   1 
ATOM   12339 O O   . PRO D 1 263 ? -37.068 1.092   -19.253 1.00 34.90  ? 263 PRO D O   1 
ATOM   12340 C CB  . PRO D 1 263 ? -37.564 3.942   -20.282 1.00 32.27  ? 263 PRO D CB  1 
ATOM   12341 C CG  . PRO D 1 263 ? -36.398 4.225   -19.372 1.00 36.38  ? 263 PRO D CG  1 
ATOM   12342 C CD  . PRO D 1 263 ? -36.972 4.249   -17.972 1.00 35.84  ? 263 PRO D CD  1 
ATOM   12343 N N   . PHE D 1 264 ? -38.959 0.885   -20.447 1.00 29.70  ? 264 PHE D N   1 
ATOM   12344 C CA  . PHE D 1 264 ? -38.767 -0.477  -20.906 1.00 29.55  ? 264 PHE D CA  1 
ATOM   12345 C C   . PHE D 1 264 ? -38.579 -0.453  -22.428 1.00 32.95  ? 264 PHE D C   1 
ATOM   12346 O O   . PHE D 1 264 ? -39.527 -0.171  -23.155 1.00 29.28  ? 264 PHE D O   1 
ATOM   12347 C CB  . PHE D 1 264 ? -40.007 -1.280  -20.513 1.00 28.69  ? 264 PHE D CB  1 
ATOM   12348 C CG  . PHE D 1 264 ? -39.942 -2.790  -20.729 1.00 30.90  ? 264 PHE D CG  1 
ATOM   12349 C CD1 . PHE D 1 264 ? -40.251 -3.355  -21.957 1.00 29.54  ? 264 PHE D CD1 1 
ATOM   12350 C CD2 . PHE D 1 264 ? -39.678 -3.640  -19.672 1.00 34.05  ? 264 PHE D CD2 1 
ATOM   12351 C CE1 . PHE D 1 264 ? -40.258 -4.725  -22.127 1.00 31.42  ? 264 PHE D CE1 1 
ATOM   12352 C CE2 . PHE D 1 264 ? -39.668 -5.006  -19.856 1.00 33.99  ? 264 PHE D CE2 1 
ATOM   12353 C CZ  . PHE D 1 264 ? -39.944 -5.542  -21.093 1.00 33.42  ? 264 PHE D CZ  1 
ATOM   12354 N N   . VAL D 1 265 ? -37.342 -0.741  -22.899 1.00 30.88  ? 265 VAL D N   1 
ATOM   12355 C CA  . VAL D 1 265 ? -37.005 -0.578  -24.312 1.00 32.05  ? 265 VAL D CA  1 
ATOM   12356 C C   . VAL D 1 265 ? -36.877 -1.959  -24.988 1.00 33.51  ? 265 VAL D C   1 
ATOM   12357 O O   . VAL D 1 265 ? -36.165 -2.835  -24.507 1.00 29.63  ? 265 VAL D O   1 
ATOM   12358 C CB  . VAL D 1 265 ? -35.722 0.238   -24.466 1.00 28.71  ? 265 VAL D CB  1 
ATOM   12359 C CG1 . VAL D 1 265 ? -35.310 0.344   -25.899 1.00 28.38  ? 265 VAL D CG1 1 
ATOM   12360 C CG2 . VAL D 1 265 ? -35.857 1.620   -23.848 1.00 30.54  ? 265 VAL D CG2 1 
ATOM   12361 N N   . VAL D 1 266 ? -37.555 -2.110  -26.133 1.00 34.53  ? 266 VAL D N   1 
ATOM   12362 C CA  . VAL D 1 266 ? -37.503 -3.330  -26.929 1.00 36.59  ? 266 VAL D CA  1 
ATOM   12363 C C   . VAL D 1 266 ? -36.899 -2.992  -28.299 1.00 40.94  ? 266 VAL D C   1 
ATOM   12364 O O   . VAL D 1 266 ? -37.526 -2.303  -29.100 1.00 44.35  ? 266 VAL D O   1 
ATOM   12365 C CB  . VAL D 1 266 ? -38.915 -3.944  -27.069 1.00 36.49  ? 266 VAL D CB  1 
ATOM   12366 C CG1 . VAL D 1 266 ? -38.908 -5.243  -27.889 1.00 32.60  ? 266 VAL D CG1 1 
ATOM   12367 C CG2 . VAL D 1 266 ? -39.568 -4.176  -25.704 1.00 36.96  ? 266 VAL D CG2 1 
ATOM   12368 N N   . LEU D 1 267 ? -35.663 -3.457  -28.541 1.00 43.84  ? 267 LEU D N   1 
ATOM   12369 C CA  . LEU D 1 267 ? -34.969 -3.194  -29.795 1.00 46.05  ? 267 LEU D CA  1 
ATOM   12370 C C   . LEU D 1 267 ? -35.423 -4.203  -30.858 1.00 42.11  ? 267 LEU D C   1 
ATOM   12371 O O   . LEU D 1 267 ? -36.130 -5.150  -30.552 1.00 38.69  ? 267 LEU D O   1 
ATOM   12372 C CB  . LEU D 1 267 ? -33.461 -3.227  -29.579 1.00 46.81  ? 267 LEU D CB  1 
ATOM   12373 C CG  . LEU D 1 267 ? -32.890 -2.114  -28.694 1.00 53.27  ? 267 LEU D CG  1 
ATOM   12374 C CD1 . LEU D 1 267 ? -31.381 -2.182  -28.657 1.00 56.27  ? 267 LEU D CD1 1 
ATOM   12375 C CD2 . LEU D 1 267 ? -33.334 -0.751  -29.159 1.00 53.81  ? 267 LEU D CD2 1 
ATOM   12376 N N   . GLY D 1 268 ? -35.021 -3.953  -32.111 1.00 38.55  ? 268 GLY D N   1 
ATOM   12377 C CA  . GLY D 1 268 ? -35.604 -4.616  -33.272 1.00 42.59  ? 268 GLY D CA  1 
ATOM   12378 C C   . GLY D 1 268 ? -35.313 -6.118  -33.301 1.00 40.15  ? 268 GLY D C   1 
ATOM   12379 O O   . GLY D 1 268 ? -36.143 -6.892  -33.737 1.00 44.59  ? 268 GLY D O   1 
ATOM   12380 N N   . ASP D 1 269 ? -34.153 -6.517  -32.778 1.00 43.51  ? 269 ASP D N   1 
ATOM   12381 C CA  . ASP D 1 269 ? -33.726 -7.910  -32.818 1.00 45.62  ? 269 ASP D CA  1 
ATOM   12382 C C   . ASP D 1 269 ? -34.208 -8.675  -31.586 1.00 44.97  ? 269 ASP D C   1 
ATOM   12383 O O   . ASP D 1 269 ? -33.831 -9.806  -31.405 1.00 50.33  ? 269 ASP D O   1 
ATOM   12384 C CB  . ASP D 1 269 ? -32.218 -8.013  -32.903 1.00 48.67  ? 269 ASP D CB  1 
ATOM   12385 C CG  . ASP D 1 269 ? -31.475 -7.350  -31.762 1.00 53.57  ? 269 ASP D CG  1 
ATOM   12386 O OD1 . ASP D 1 269 ? -31.989 -6.356  -31.249 1.00 59.12  ? 269 ASP D OD1 1 
ATOM   12387 O OD2 . ASP D 1 269 ? -30.381 -7.830  -31.409 1.00 63.91  ? 269 ASP D OD2 1 
ATOM   12388 N N   . ALA D 1 270 ? -35.059 -8.061  -30.748 1.00 46.24  ? 270 ALA D N   1 
ATOM   12389 C CA  . ALA D 1 270 ? -35.457 -8.693  -29.480 1.00 44.50  ? 270 ALA D CA  1 
ATOM   12390 C C   . ALA D 1 270 ? -36.262 -9.983  -29.726 1.00 48.21  ? 270 ALA D C   1 
ATOM   12391 O O   . ALA D 1 270 ? -36.927 -10.132 -30.762 1.00 46.60  ? 270 ALA D O   1 
ATOM   12392 C CB  . ALA D 1 270 ? -36.238 -7.721  -28.623 1.00 41.61  ? 270 ALA D CB  1 
ATOM   12393 N N   . ASP D 1 271 ? -36.210 -10.909 -28.738 1.00 46.33  ? 271 ASP D N   1 
ATOM   12394 C CA  . ASP D 1 271 ? -37.153 -12.020 -28.681 1.00 47.62  ? 271 ASP D CA  1 
ATOM   12395 C C   . ASP D 1 271 ? -38.538 -11.485 -28.291 1.00 49.11  ? 271 ASP D C   1 
ATOM   12396 O O   . ASP D 1 271 ? -38.769 -11.127 -27.139 1.00 43.56  ? 271 ASP D O   1 
ATOM   12397 C CB  . ASP D 1 271 ? -36.688 -13.106 -27.725 1.00 51.05  ? 271 ASP D CB  1 
ATOM   12398 C CG  . ASP D 1 271 ? -37.542 -14.366 -27.716 1.00 56.42  ? 271 ASP D CG  1 
ATOM   12399 O OD1 . ASP D 1 271 ? -38.740 -14.269 -27.368 1.00 59.35  ? 271 ASP D OD1 1 
ATOM   12400 O OD2 . ASP D 1 271 ? -37.007 -15.429 -28.058 1.00 70.86  ? 271 ASP D OD2 1 
ATOM   12401 N N   . LEU D 1 272 ? -39.468 -11.505 -29.248 1.00 48.43  ? 272 LEU D N   1 
ATOM   12402 C CA  . LEU D 1 272 ? -40.761 -10.845 -29.092 1.00 51.40  ? 272 LEU D CA  1 
ATOM   12403 C C   . LEU D 1 272 ? -41.526 -11.423 -27.904 1.00 49.02  ? 272 LEU D C   1 
ATOM   12404 O O   . LEU D 1 272 ? -42.053 -10.683 -27.094 1.00 50.36  ? 272 LEU D O   1 
ATOM   12405 C CB  . LEU D 1 272 ? -41.585 -10.959 -30.377 1.00 47.86  ? 272 LEU D CB  1 
ATOM   12406 C CG  . LEU D 1 272 ? -42.965 -10.293 -30.340 1.00 56.42  ? 272 LEU D CG  1 
ATOM   12407 C CD1 . LEU D 1 272 ? -42.887 -8.775  -29.993 1.00 57.66  ? 272 LEU D CD1 1 
ATOM   12408 C CD2 . LEU D 1 272 ? -43.685 -10.501 -31.648 1.00 55.95  ? 272 LEU D CD2 1 
ATOM   12409 N N   . GLU D 1 273 ? -41.667 -12.737 -27.870 1.00 53.33  ? 273 GLU D N   1 
ATOM   12410 C CA  . GLU D 1 273 ? -42.508 -13.389 -26.874 1.00 52.82  ? 273 GLU D CA  1 
ATOM   12411 C C   . GLU D 1 273 ? -41.952 -13.089 -25.488 1.00 45.34  ? 273 GLU D C   1 
ATOM   12412 O O   . GLU D 1 273 ? -42.710 -12.820 -24.554 1.00 44.03  ? 273 GLU D O   1 
ATOM   12413 C CB  . GLU D 1 273 ? -42.592 -14.899 -27.143 1.00 60.15  ? 273 GLU D CB  1 
ATOM   12414 C CG  . GLU D 1 273 ? -43.931 -15.519 -26.739 1.00 72.71  ? 273 GLU D CG  1 
ATOM   12415 C CD  . GLU D 1 273 ? -45.156 -14.653 -27.050 1.00 80.34  ? 273 GLU D CD  1 
ATOM   12416 O OE1 . GLU D 1 273 ? -45.449 -14.434 -28.247 1.00 85.83  ? 273 GLU D OE1 1 
ATOM   12417 O OE2 . GLU D 1 273 ? -45.787 -14.166 -26.088 1.00 79.80  ? 273 GLU D OE2 1 
ATOM   12418 N N   . GLN D 1 274 ? -40.623 -13.118 -25.371 1.00 40.72  ? 274 GLN D N   1 
ATOM   12419 C CA  . GLN D 1 274 ? -39.973 -12.913 -24.094 1.00 42.51  ? 274 GLN D CA  1 
ATOM   12420 C C   . GLN D 1 274 ? -40.139 -11.452 -23.658 1.00 39.17  ? 274 GLN D C   1 
ATOM   12421 O O   . GLN D 1 274 ? -40.321 -11.175 -22.484 1.00 39.13  ? 274 GLN D O   1 
ATOM   12422 C CB  . GLN D 1 274 ? -38.503 -13.281 -24.174 1.00 56.13  ? 274 GLN D CB  1 
ATOM   12423 C CG  . GLN D 1 274 ? -38.211 -14.761 -23.952 1.00 68.11  ? 274 GLN D CG  1 
ATOM   12424 C CD  . GLN D 1 274 ? -36.794 -15.124 -24.352 1.00 83.29  ? 274 GLN D CD  1 
ATOM   12425 O OE1 . GLN D 1 274 ? -35.816 -14.526 -23.876 1.00 82.98  ? 274 GLN D OE1 1 
ATOM   12426 N NE2 . GLN D 1 274 ? -36.672 -16.042 -25.300 1.00 89.80  ? 274 GLN D NE2 1 
ATOM   12427 N N   . ALA D 1 275 ? -40.088 -10.528 -24.616 1.00 34.66  ? 275 ALA D N   1 
ATOM   12428 C CA  . ALA D 1 275 ? -40.243 -9.122  -24.309 1.00 33.62  ? 275 ALA D CA  1 
ATOM   12429 C C   . ALA D 1 275 ? -41.656 -8.860  -23.797 1.00 32.65  ? 275 ALA D C   1 
ATOM   12430 O O   . ALA D 1 275 ? -41.842 -8.159  -22.774 1.00 31.89  ? 275 ALA D O   1 
ATOM   12431 C CB  . ALA D 1 275 ? -39.917 -8.274  -25.507 1.00 34.38  ? 275 ALA D CB  1 
ATOM   12432 N N   . VAL D 1 276 ? -42.645 -9.478  -24.448 1.00 31.89  ? 276 VAL D N   1 
ATOM   12433 C CA  . VAL D 1 276 ? -44.042 -9.264  -24.065 1.00 33.40  ? 276 VAL D CA  1 
ATOM   12434 C C   . VAL D 1 276 ? -44.275 -9.783  -22.624 1.00 34.64  ? 276 VAL D C   1 
ATOM   12435 O O   . VAL D 1 276 ? -44.836 -9.062  -21.788 1.00 33.33  ? 276 VAL D O   1 
ATOM   12436 C CB  . VAL D 1 276 ? -45.016 -9.887  -25.055 1.00 31.87  ? 276 VAL D CB  1 
ATOM   12437 C CG1 . VAL D 1 276 ? -46.428 -9.927  -24.503 1.00 38.26  ? 276 VAL D CG1 1 
ATOM   12438 C CG2 . VAL D 1 276 ? -44.994 -9.168  -26.366 1.00 33.72  ? 276 VAL D CG2 1 
ATOM   12439 N N   . SER D 1 277 ? -43.804 -11.007 -22.332 1.00 34.45  ? 277 SER D N   1 
ATOM   12440 C CA  . SER D 1 277 ? -44.003 -11.608 -21.009 1.00 37.36  ? 277 SER D CA  1 
ATOM   12441 C C   . SER D 1 277 ? -43.350 -10.747 -19.932 1.00 37.12  ? 277 SER D C   1 
ATOM   12442 O O   . SER D 1 277 ? -43.964 -10.474 -18.911 1.00 37.14  ? 277 SER D O   1 
ATOM   12443 C CB  . SER D 1 277 ? -43.496 -12.999 -20.942 1.00 34.68  ? 277 SER D CB  1 
ATOM   12444 O OG  . SER D 1 277 ? -43.972 -13.746 -22.029 1.00 45.18  ? 277 SER D OG  1 
ATOM   12445 N N   . ALA D 1 278 ? -42.119 -10.296 -20.184 1.00 35.77  ? 278 ALA D N   1 
ATOM   12446 C CA  . ALA D 1 278 ? -41.394 -9.512  -19.201 1.00 33.60  ? 278 ALA D CA  1 
ATOM   12447 C C   . ALA D 1 278 ? -42.122 -8.196  -18.942 1.00 35.88  ? 278 ALA D C   1 
ATOM   12448 O O   . ALA D 1 278 ? -42.168 -7.741  -17.816 1.00 40.35  ? 278 ALA D O   1 
ATOM   12449 C CB  . ALA D 1 278 ? -39.988 -9.279  -19.651 1.00 33.50  ? 278 ALA D CB  1 
ATOM   12450 N N   . ALA D 1 279 ? -42.702 -7.593  -19.998 1.00 35.38  ? 279 ALA D N   1 
ATOM   12451 C CA  . ALA D 1 279 ? -43.404 -6.315  -19.852 1.00 32.83  ? 279 ALA D CA  1 
ATOM   12452 C C   . ALA D 1 279 ? -44.654 -6.504  -19.011 1.00 33.82  ? 279 ALA D C   1 
ATOM   12453 O O   . ALA D 1 279 ? -44.952 -5.698  -18.161 1.00 40.19  ? 279 ALA D O   1 
ATOM   12454 C CB  . ALA D 1 279 ? -43.744 -5.737  -21.191 1.00 32.95  ? 279 ALA D CB  1 
ATOM   12455 N N   . VAL D 1 280 ? -45.370 -7.576  -19.241 1.00 32.54  ? 280 VAL D N   1 
ATOM   12456 C CA  . VAL D 1 280 ? -46.609 -7.799  -18.528 1.00 36.97  ? 280 VAL D CA  1 
ATOM   12457 C C   . VAL D 1 280 ? -46.304 -8.065  -17.053 1.00 42.20  ? 280 VAL D C   1 
ATOM   12458 O O   . VAL D 1 280 ? -46.979 -7.515  -16.183 1.00 41.18  ? 280 VAL D O   1 
ATOM   12459 C CB  . VAL D 1 280 ? -47.441 -8.931  -19.132 1.00 35.57  ? 280 VAL D CB  1 
ATOM   12460 C CG1 . VAL D 1 280 ? -48.663 -9.237  -18.272 1.00 35.97  ? 280 VAL D CG1 1 
ATOM   12461 C CG2 . VAL D 1 280 ? -47.849 -8.616  -20.559 1.00 34.64  ? 280 VAL D CG2 1 
ATOM   12462 N N   . PHE D 1 281 ? -45.274 -8.903  -16.783 1.00 41.08  ? 281 PHE D N   1 
ATOM   12463 C CA  . PHE D 1 281 ? -44.893 -9.241  -15.412 1.00 45.54  ? 281 PHE D CA  1 
ATOM   12464 C C   . PHE D 1 281 ? -44.417 -7.986  -14.697 1.00 44.45  ? 281 PHE D C   1 
ATOM   12465 O O   . PHE D 1 281 ? -44.795 -7.737  -13.565 1.00 50.92  ? 281 PHE D O   1 
ATOM   12466 C CB  . PHE D 1 281 ? -43.823 -10.334 -15.354 1.00 51.50  ? 281 PHE D CB  1 
ATOM   12467 C CG  . PHE D 1 281 ? -44.387 -11.744 -15.460 1.00 62.72  ? 281 PHE D CG  1 
ATOM   12468 C CD1 . PHE D 1 281 ? -44.419 -12.583 -14.351 1.00 70.40  ? 281 PHE D CD1 1 
ATOM   12469 C CD2 . PHE D 1 281 ? -44.963 -12.207 -16.663 1.00 70.09  ? 281 PHE D CD2 1 
ATOM   12470 C CE1 . PHE D 1 281 ? -44.968 -13.871 -14.446 1.00 80.92  ? 281 PHE D CE1 1 
ATOM   12471 C CE2 . PHE D 1 281 ? -45.507 -13.490 -16.752 1.00 74.29  ? 281 PHE D CE2 1 
ATOM   12472 C CZ  . PHE D 1 281 ? -45.511 -14.318 -15.645 1.00 79.55  ? 281 PHE D CZ  1 
ATOM   12473 N N   . GLY D 1 282 ? -43.619 -7.187  -15.381 1.00 40.38  ? 282 GLY D N   1 
ATOM   12474 C CA  . GLY D 1 282 ? -43.051 -5.985  -14.786 1.00 41.55  ? 282 GLY D CA  1 
ATOM   12475 C C   . GLY D 1 282 ? -44.127 -4.950  -14.429 1.00 47.23  ? 282 GLY D C   1 
ATOM   12476 O O   . GLY D 1 282 ? -44.165 -4.459  -13.310 1.00 53.73  ? 282 GLY D O   1 
ATOM   12477 N N   . LYS D 1 283 ? -44.998 -4.634  -15.393 1.00 42.55  ? 283 LYS D N   1 
ATOM   12478 C CA  . LYS D 1 283 ? -45.970 -3.585  -15.218 1.00 36.91  ? 283 LYS D CA  1 
ATOM   12479 C C   . LYS D 1 283 ? -47.099 -4.037  -14.274 1.00 39.66  ? 283 LYS D C   1 
ATOM   12480 O O   . LYS D 1 283 ? -47.493 -3.278  -13.393 1.00 39.57  ? 283 LYS D O   1 
ATOM   12481 C CB  . LYS D 1 283 ? -46.529 -3.137  -16.562 1.00 37.19  ? 283 LYS D CB  1 
ATOM   12482 C CG  . LYS D 1 283 ? -47.662 -2.144  -16.464 1.00 39.13  ? 283 LYS D CG  1 
ATOM   12483 C CD  . LYS D 1 283 ? -47.199 -0.764  -16.015 1.00 39.45  ? 283 LYS D CD  1 
ATOM   12484 C CE  . LYS D 1 283 ? -48.207 -0.038  -15.181 1.00 40.67  ? 283 LYS D CE  1 
ATOM   12485 N NZ  . LYS D 1 283 ? -47.540 0.935   -14.329 1.00 42.51  ? 283 LYS D NZ  1 
ATOM   12486 N N   . PHE D 1 284 ? -47.696 -5.202  -14.530 1.00 38.27  ? 284 PHE D N   1 
ATOM   12487 C CA  . PHE D 1 284 ? -48.924 -5.566  -13.765 1.00 40.46  ? 284 PHE D CA  1 
ATOM   12488 C C   . PHE D 1 284 ? -48.641 -6.499  -12.592 1.00 45.35  ? 284 PHE D C   1 
ATOM   12489 O O   . PHE D 1 284 ? -48.989 -6.158  -11.445 1.00 52.47  ? 284 PHE D O   1 
ATOM   12490 C CB  . PHE D 1 284 ? -49.919 -6.117  -14.790 1.00 37.59  ? 284 PHE D CB  1 
ATOM   12491 C CG  . PHE D 1 284 ? -50.232 -5.137  -15.912 1.00 36.85  ? 284 PHE D CG  1 
ATOM   12492 C CD1 . PHE D 1 284 ? -51.055 -4.040  -15.689 1.00 37.80  ? 284 PHE D CD1 1 
ATOM   12493 C CD2 . PHE D 1 284 ? -49.696 -5.309  -17.183 1.00 37.35  ? 284 PHE D CD2 1 
ATOM   12494 C CE1 . PHE D 1 284 ? -51.338 -3.146  -16.709 1.00 40.25  ? 284 PHE D CE1 1 
ATOM   12495 C CE2 . PHE D 1 284 ? -49.982 -4.411  -18.198 1.00 38.16  ? 284 PHE D CE2 1 
ATOM   12496 C CZ  . PHE D 1 284 ? -50.802 -3.334  -17.960 1.00 37.71  ? 284 PHE D CZ  1 
ATOM   12497 N N   . LEU D 1 285 ? -48.046 -7.654  -12.866 1.00 51.80  ? 285 LEU D N   1 
ATOM   12498 C CA  . LEU D 1 285 ? -47.755 -8.623  -11.782 1.00 61.55  ? 285 LEU D CA  1 
ATOM   12499 C C   . LEU D 1 285 ? -46.778 -7.914  -10.839 1.00 77.88  ? 285 LEU D C   1 
ATOM   12500 O O   . LEU D 1 285 ? -46.889 -8.157  -9.619  1.00 77.51  ? 285 LEU D O   1 
ATOM   12501 C CB  . LEU D 1 285 ? -47.231 -9.920  -12.389 1.00 55.78  ? 285 LEU D CB  1 
ATOM   12502 C CG  . LEU D 1 285 ? -48.138 -10.526 -13.467 1.00 53.89  ? 285 LEU D CG  1 
ATOM   12503 C CD1 . LEU D 1 285 ? -47.800 -11.968 -13.757 1.00 53.08  ? 285 LEU D CD1 1 
ATOM   12504 C CD2 . LEU D 1 285 ? -49.602 -10.413 -13.079 1.00 52.48  ? 285 LEU D CD2 1 
ATOM   12505 N N   . HIS D 1 286 ? -45.821 -7.158  -11.390 1.00 101.64 ? 286 HIS D N   1 
ATOM   12506 C CA  . HIS D 1 286 ? -44.913 -6.285  -10.586 1.00 108.16 ? 286 HIS D CA  1 
ATOM   12507 C C   . HIS D 1 286 ? -43.743 -7.063  -9.979  1.00 110.81 ? 286 HIS D C   1 
ATOM   12508 O O   . HIS D 1 286 ? -43.616 -8.283  -10.217 1.00 119.42 ? 286 HIS D O   1 
ATOM   12509 C CB  . HIS D 1 286 ? -45.690 -5.450  -9.558  1.00 104.70 ? 286 HIS D CB  1 
ATOM   12510 C CG  . HIS D 1 286 ? -45.272 -4.022  -9.525  1.00 101.03 ? 286 HIS D CG  1 
ATOM   12511 N ND1 . HIS D 1 286 ? -45.781 -3.109  -8.629  1.00 111.39 ? 286 HIS D ND1 1 
ATOM   12512 C CD2 . HIS D 1 286 ? -44.389 -3.354  -10.274 1.00 111.58 ? 286 HIS D CD2 1 
ATOM   12513 C CE1 . HIS D 1 286 ? -45.216 -1.930  -8.840  1.00 117.73 ? 286 HIS D CE1 1 
ATOM   12514 N NE2 . HIS D 1 286 ? -44.368 -2.056  -9.835  1.00 112.52 ? 286 HIS D NE2 1 
ATOM   12515 N N   . GLN D 1 287 ? -42.916 -6.355  -9.207  1.00 113.69 ? 287 GLN D N   1 
ATOM   12516 C CA  . GLN D 1 287 ? -41.723 -6.978  -8.584  1.00 119.55 ? 287 GLN D CA  1 
ATOM   12517 C C   . GLN D 1 287 ? -42.100 -8.363  -8.042  1.00 117.41 ? 287 GLN D C   1 
ATOM   12518 O O   . GLN D 1 287 ? -41.208 -9.238  -8.057  1.00 97.72  ? 287 GLN D O   1 
ATOM   12519 C CB  . GLN D 1 287 ? -41.215 -6.053  -7.480  1.00 108.58 ? 287 GLN D CB  1 
ATOM   12520 C CG  . GLN D 1 287 ? -40.581 -4.765  -7.993  1.00 114.69 ? 287 GLN D CG  1 
ATOM   12521 C CD  . GLN D 1 287 ? -41.540 -3.597  -8.062  1.00 127.66 ? 287 GLN D CD  1 
ATOM   12522 O OE1 . GLN D 1 287 ? -41.285 -2.589  -8.730  1.00 137.54 ? 287 GLN D OE1 1 
ATOM   12523 N NE2 . GLN D 1 287 ? -42.659 -3.722  -7.364  1.00 131.93 ? 287 GLN D NE2 1 
ATOM   12524 N N   . ALA D 1 293 ? -39.863 -1.168  -11.354 1.00 87.63  ? 293 ALA D N   1 
ATOM   12525 C CA  . ALA D 1 293 ? -41.133 -1.047  -12.040 1.00 85.80  ? 293 ALA D CA  1 
ATOM   12526 C C   . ALA D 1 293 ? -40.929 -0.614  -13.505 1.00 84.05  ? 293 ALA D C   1 
ATOM   12527 O O   . ALA D 1 293 ? -39.794 -0.437  -13.976 1.00 67.54  ? 293 ALA D O   1 
ATOM   12528 C CB  . ALA D 1 293 ? -42.027 -0.068  -11.277 1.00 85.41  ? 293 ALA D CB  1 
ATOM   12529 N N   . ILE D 1 294 ? -42.070 -0.468  -14.206 1.00 78.88  ? 294 ILE D N   1 
ATOM   12530 C CA  . ILE D 1 294 ? -42.133 -0.087  -15.605 1.00 65.48  ? 294 ILE D CA  1 
ATOM   12531 C C   . ILE D 1 294 ? -43.311 0.863   -15.764 1.00 54.95  ? 294 ILE D C   1 
ATOM   12532 O O   . ILE D 1 294 ? -44.424 0.504   -15.408 1.00 61.76  ? 294 ILE D O   1 
ATOM   12533 C CB  . ILE D 1 294 ? -42.326 -1.334  -16.495 1.00 67.86  ? 294 ILE D CB  1 
ATOM   12534 C CG1 . ILE D 1 294 ? -41.295 -2.398  -16.224 1.00 72.47  ? 294 ILE D CG1 1 
ATOM   12535 C CG2 . ILE D 1 294 ? -42.370 -0.958  -17.973 1.00 61.64  ? 294 ILE D CG2 1 
ATOM   12536 C CD1 . ILE D 1 294 ? -41.609 -3.727  -16.889 1.00 71.14  ? 294 ILE D CD1 1 
ATOM   12537 N N   . ASN D 1 295 ? -43.072 2.042   -16.362 1.00 46.98  ? 295 ASN D N   1 
ATOM   12538 C CA  . ASN D 1 295 ? -44.130 3.031   -16.571 1.00 51.93  ? 295 ASN D CA  1 
ATOM   12539 C C   . ASN D 1 295 ? -44.300 3.373   -18.068 1.00 50.90  ? 295 ASN D C   1 
ATOM   12540 O O   . ASN D 1 295 ? -45.350 3.884   -18.460 1.00 58.55  ? 295 ASN D O   1 
ATOM   12541 C CB  . ASN D 1 295 ? -43.866 4.283   -15.748 1.00 61.10  ? 295 ASN D CB  1 
ATOM   12542 C CG  . ASN D 1 295 ? -43.513 3.949   -14.307 1.00 66.19  ? 295 ASN D CG  1 
ATOM   12543 O OD1 . ASN D 1 295 ? -42.373 3.551   -14.011 1.00 71.56  ? 295 ASN D OD1 1 
ATOM   12544 N ND2 . ASN D 1 295 ? -44.470 4.090   -13.403 1.00 69.03  ? 295 ASN D ND2 1 
ATOM   12545 N N   . ARG D 1 296 ? -43.249 3.101   -18.891 1.00 48.94  ? 296 ARG D N   1 
ATOM   12546 C CA  . ARG D 1 296 ? -43.233 3.423   -20.330 1.00 38.53  ? 296 ARG D CA  1 
ATOM   12547 C C   . ARG D 1 296 ? -42.598 2.272   -21.097 1.00 36.27  ? 296 ARG D C   1 
ATOM   12548 O O   . ARG D 1 296 ? -41.528 1.807   -20.717 1.00 35.71  ? 296 ARG D O   1 
ATOM   12549 C CB  . ARG D 1 296 ? -42.476 4.727   -20.591 1.00 50.00  ? 296 ARG D CB  1 
ATOM   12550 C CG  . ARG D 1 296 ? -43.189 5.679   -21.538 1.00 50.00  ? 296 ARG D CG  1 
ATOM   12551 C CD  . ARG D 1 296 ? -42.415 6.953   -21.835 1.00 50.00  ? 296 ARG D CD  1 
ATOM   12552 N NE  . ARG D 1 296 ? -41.306 7.151   -20.907 1.00 50.00  ? 296 ARG D NE  1 
ATOM   12553 C CZ  . ARG D 1 296 ? -40.408 8.119   -21.015 1.00 50.00  ? 296 ARG D CZ  1 
ATOM   12554 N NH1 . ARG D 1 296 ? -40.485 8.990   -22.013 1.00 50.00  ? 296 ARG D NH1 1 
ATOM   12555 N NH2 . ARG D 1 296 ? -39.431 8.223   -20.123 1.00 50.00  ? 296 ARG D NH2 1 
ATOM   12556 N N   . ILE D 1 297 ? -43.207 1.895   -22.245 1.00 35.40  ? 297 ILE D N   1 
ATOM   12557 C CA  . ILE D 1 297 ? -42.641 0.866   -23.114 1.00 31.67  ? 297 ILE D CA  1 
ATOM   12558 C C   . ILE D 1 297 ? -42.346 1.463   -24.495 1.00 30.43  ? 297 ILE D C   1 
ATOM   12559 O O   . ILE D 1 297 ? -43.238 1.938   -25.173 1.00 27.48  ? 297 ILE D O   1 
ATOM   12560 C CB  . ILE D 1 297 ? -43.560 -0.351  -23.208 1.00 33.22  ? 297 ILE D CB  1 
ATOM   12561 C CG1 . ILE D 1 297 ? -43.871 -0.924  -21.820 1.00 34.36  ? 297 ILE D CG1 1 
ATOM   12562 C CG2 . ILE D 1 297 ? -42.966 -1.428  -24.153 1.00 32.43  ? 297 ILE D CG2 1 
ATOM   12563 C CD1 . ILE D 1 297 ? -44.923 -2.035  -21.826 1.00 36.10  ? 297 ILE D CD1 1 
ATOM   12564 N N   . ILE D 1 298 ? -41.057 1.391   -24.893 1.00 30.95  ? 298 ILE D N   1 
ATOM   12565 C CA  . ILE D 1 298 ? -40.558 1.925   -26.152 1.00 30.09  ? 298 ILE D CA  1 
ATOM   12566 C C   . ILE D 1 298 ? -40.122 0.760   -27.031 1.00 30.20  ? 298 ILE D C   1 
ATOM   12567 O O   . ILE D 1 298 ? -39.247 -0.014  -26.641 1.00 31.53  ? 298 ILE D O   1 
ATOM   12568 C CB  . ILE D 1 298 ? -39.392 2.914   -25.883 1.00 29.87  ? 298 ILE D CB  1 
ATOM   12569 C CG1 . ILE D 1 298 ? -39.878 4.145   -25.141 1.00 28.75  ? 298 ILE D CG1 1 
ATOM   12570 C CG2 . ILE D 1 298 ? -38.635 3.296   -27.174 1.00 28.44  ? 298 ILE D CG2 1 
ATOM   12571 C CD1 . ILE D 1 298 ? -38.842 4.728   -24.191 1.00 28.67  ? 298 ILE D CD1 1 
ATOM   12572 N N   . VAL D 1 299 ? -40.705 0.678   -28.239 1.00 33.83  ? 299 VAL D N   1 
ATOM   12573 C CA  . VAL D 1 299 ? -40.426 -0.417  -29.173 1.00 35.88  ? 299 VAL D CA  1 
ATOM   12574 C C   . VAL D 1 299 ? -39.943 0.157   -30.514 1.00 36.33  ? 299 VAL D C   1 
ATOM   12575 O O   . VAL D 1 299 ? -40.510 1.094   -31.039 1.00 36.78  ? 299 VAL D O   1 
ATOM   12576 C CB  . VAL D 1 299 ? -41.652 -1.314  -29.377 1.00 32.02  ? 299 VAL D CB  1 
ATOM   12577 C CG1 . VAL D 1 299 ? -41.294 -2.625  -30.080 1.00 33.60  ? 299 VAL D CG1 1 
ATOM   12578 C CG2 . VAL D 1 299 ? -42.359 -1.598  -28.080 1.00 30.83  ? 299 VAL D CG2 1 
ATOM   12579 N N   . GLU D 1 300 ? -38.907 -0.449  -31.062 1.00 41.33  ? 300 GLU D N   1 
ATOM   12580 C CA  . GLU D 1 300 ? -38.436 -0.120  -32.391 1.00 42.84  ? 300 GLU D CA  1 
ATOM   12581 C C   . GLU D 1 300 ? -39.555 -0.377  -33.399 1.00 39.55  ? 300 GLU D C   1 
ATOM   12582 O O   . GLU D 1 300 ? -40.340 -1.332  -33.263 1.00 37.88  ? 300 GLU D O   1 
ATOM   12583 C CB  . GLU D 1 300 ? -37.189 -0.946  -32.713 1.00 50.70  ? 300 GLU D CB  1 
ATOM   12584 C CG  . GLU D 1 300 ? -36.392 -0.414  -33.904 1.00 59.30  ? 300 GLU D CG  1 
ATOM   12585 C CD  . GLU D 1 300 ? -34.904 -0.780  -33.905 1.00 66.88  ? 300 GLU D CD  1 
ATOM   12586 O OE1 . GLU D 1 300 ? -34.463 -1.653  -33.102 1.00 65.28  ? 300 GLU D OE1 1 
ATOM   12587 O OE2 . GLU D 1 300 ? -34.171 -0.147  -34.691 1.00 81.58  ? 300 GLU D OE2 1 
ATOM   12588 N N   . ASP D 1 301 ? -39.605 0.474   -34.419 1.00 39.97  ? 301 ASP D N   1 
ATOM   12589 C CA  . ASP D 1 301 ? -40.734 0.552   -35.329 1.00 41.12  ? 301 ASP D CA  1 
ATOM   12590 C C   . ASP D 1 301 ? -41.047 -0.816  -35.971 1.00 39.28  ? 301 ASP D C   1 
ATOM   12591 O O   . ASP D 1 301 ? -42.207 -1.160  -36.162 1.00 42.36  ? 301 ASP D O   1 
ATOM   12592 C CB  . ASP D 1 301 ? -40.482 1.582   -36.397 1.00 48.15  ? 301 ASP D CB  1 
ATOM   12593 C CG  . ASP D 1 301 ? -41.457 1.536   -37.551 1.00 52.70  ? 301 ASP D CG  1 
ATOM   12594 O OD1 . ASP D 1 301 ? -42.626 1.950   -37.339 1.00 56.89  ? 301 ASP D OD1 1 
ATOM   12595 O OD2 . ASP D 1 301 ? -41.071 0.994   -38.619 1.00 53.49  ? 301 ASP D OD2 1 
ATOM   12596 N N   . SER D 1 302 ? -40.016 -1.562  -36.329 1.00 38.08  ? 302 SER D N   1 
ATOM   12597 C CA  . SER D 1 302 ? -40.187 -2.859  -36.976 1.00 42.63  ? 302 SER D CA  1 
ATOM   12598 C C   . SER D 1 302 ? -40.924 -3.847  -36.060 1.00 42.13  ? 302 SER D C   1 
ATOM   12599 O O   . SER D 1 302 ? -41.658 -4.708  -36.545 1.00 38.06  ? 302 SER D O   1 
ATOM   12600 C CB  . SER D 1 302 ? -38.860 -3.419  -37.415 1.00 48.12  ? 302 SER D CB  1 
ATOM   12601 O OG  . SER D 1 302 ? -37.921 -3.406  -36.340 1.00 54.01  ? 302 SER D OG  1 
ATOM   12602 N N   . LEU D 1 303 ? -40.745 -3.723  -34.734 1.00 38.29  ? 303 LEU D N   1 
ATOM   12603 C CA  . LEU D 1 303 ? -41.391 -4.663  -33.818 1.00 39.41  ? 303 LEU D CA  1 
ATOM   12604 C C   . LEU D 1 303 ? -42.709 -4.107  -33.252 1.00 39.11  ? 303 LEU D C   1 
ATOM   12605 O O   . LEU D 1 303 ? -43.464 -4.862  -32.633 1.00 38.29  ? 303 LEU D O   1 
ATOM   12606 C CB  . LEU D 1 303 ? -40.454 -5.059  -32.693 1.00 43.50  ? 303 LEU D CB  1 
ATOM   12607 C CG  . LEU D 1 303 ? -39.718 -6.377  -32.872 1.00 51.51  ? 303 LEU D CG  1 
ATOM   12608 C CD1 . LEU D 1 303 ? -38.942 -6.695  -31.581 1.00 51.98  ? 303 LEU D CD1 1 
ATOM   12609 C CD2 . LEU D 1 303 ? -40.679 -7.517  -33.248 1.00 50.05  ? 303 LEU D CD2 1 
ATOM   12610 N N   . TYR D 1 304 ? -42.970 -2.794  -33.420 1.00 35.89  ? 304 TYR D N   1 
ATOM   12611 C CA  . TYR D 1 304 ? -43.976 -2.105  -32.597 1.00 34.81  ? 304 TYR D CA  1 
ATOM   12612 C C   . TYR D 1 304 ? -45.373 -2.742  -32.782 1.00 35.44  ? 304 TYR D C   1 
ATOM   12613 O O   . TYR D 1 304 ? -46.025 -3.106  -31.790 1.00 37.61  ? 304 TYR D O   1 
ATOM   12614 C CB  . TYR D 1 304 ? -44.037 -0.606  -32.892 1.00 35.63  ? 304 TYR D CB  1 
ATOM   12615 C CG  . TYR D 1 304 ? -45.134 0.133   -32.122 1.00 35.20  ? 304 TYR D CG  1 
ATOM   12616 C CD1 . TYR D 1 304 ? -44.866 0.760   -30.910 1.00 32.16  ? 304 TYR D CD1 1 
ATOM   12617 C CD2 . TYR D 1 304 ? -46.445 0.211   -32.623 1.00 37.26  ? 304 TYR D CD2 1 
ATOM   12618 C CE1 . TYR D 1 304 ? -45.860 1.435   -30.213 1.00 34.24  ? 304 TYR D CE1 1 
ATOM   12619 C CE2 . TYR D 1 304 ? -47.452 0.855   -31.922 1.00 34.72  ? 304 TYR D CE2 1 
ATOM   12620 C CZ  . TYR D 1 304 ? -47.161 1.482   -30.726 1.00 35.61  ? 304 TYR D CZ  1 
ATOM   12621 O OH  . TYR D 1 304 ? -48.169 2.107   -30.038 1.00 35.22  ? 304 TYR D OH  1 
ATOM   12622 N N   . ASP D 1 305 ? -45.863 -2.806  -34.028 1.00 32.13  ? 305 ASP D N   1 
ATOM   12623 C CA  . ASP D 1 305 ? -47.230 -3.280  -34.288 1.00 35.48  ? 305 ASP D CA  1 
ATOM   12624 C C   . ASP D 1 305 ? -47.444 -4.674  -33.677 1.00 39.87  ? 305 ASP D C   1 
ATOM   12625 O O   . ASP D 1 305 ? -48.465 -4.926  -33.059 1.00 46.74  ? 305 ASP D O   1 
ATOM   12626 C CB  . ASP D 1 305 ? -47.575 -3.254  -35.767 1.00 33.81  ? 305 ASP D CB  1 
ATOM   12627 C CG  . ASP D 1 305 ? -47.510 -1.886  -36.445 1.00 40.40  ? 305 ASP D CG  1 
ATOM   12628 O OD1 . ASP D 1 305 ? -47.414 -0.852  -35.723 1.00 42.14  ? 305 ASP D OD1 1 
ATOM   12629 O OD2 . ASP D 1 305 ? -47.512 -1.858  -37.679 1.00 49.61  ? 305 ASP D OD2 1 
ATOM   12630 N N   . ALA D 1 306 ? -46.493 -5.585  -33.873 1.00 40.00  ? 306 ALA D N   1 
ATOM   12631 C CA  . ALA D 1 306 ? -46.663 -6.954  -33.388 1.00 39.34  ? 306 ALA D CA  1 
ATOM   12632 C C   . ALA D 1 306 ? -46.611 -6.984  -31.856 1.00 40.83  ? 306 ALA D C   1 
ATOM   12633 O O   . ALA D 1 306 ? -47.349 -7.741  -31.224 1.00 39.33  ? 306 ALA D O   1 
ATOM   12634 C CB  . ALA D 1 306 ? -45.621 -7.857  -33.990 1.00 37.24  ? 306 ALA D CB  1 
ATOM   12635 N N   . PHE D 1 307 ? -45.755 -6.141  -31.266 1.00 37.86  ? 307 PHE D N   1 
ATOM   12636 C CA  . PHE D 1 307 ? -45.644 -6.070  -29.816 1.00 37.24  ? 307 PHE D CA  1 
ATOM   12637 C C   . PHE D 1 307 ? -46.978 -5.617  -29.212 1.00 32.53  ? 307 PHE D C   1 
ATOM   12638 O O   . PHE D 1 307 ? -47.480 -6.243  -28.253 1.00 29.33  ? 307 PHE D O   1 
ATOM   12639 C CB  . PHE D 1 307 ? -44.503 -5.148  -29.391 1.00 35.31  ? 307 PHE D CB  1 
ATOM   12640 C CG  . PHE D 1 307 ? -44.262 -5.161  -27.900 1.00 32.54  ? 307 PHE D CG  1 
ATOM   12641 C CD1 . PHE D 1 307 ? -44.972 -4.323  -27.061 1.00 35.84  ? 307 PHE D CD1 1 
ATOM   12642 C CD2 . PHE D 1 307 ? -43.377 -6.054  -27.330 1.00 36.46  ? 307 PHE D CD2 1 
ATOM   12643 C CE1 . PHE D 1 307 ? -44.789 -4.372  -25.688 1.00 36.00  ? 307 PHE D CE1 1 
ATOM   12644 C CE2 . PHE D 1 307 ? -43.176 -6.074  -25.956 1.00 38.52  ? 307 PHE D CE2 1 
ATOM   12645 C CZ  . PHE D 1 307 ? -43.893 -5.240  -25.144 1.00 35.85  ? 307 PHE D CZ  1 
ATOM   12646 N N   . ALA D 1 308 ? -47.550 -4.554  -29.790 1.00 32.30  ? 308 ALA D N   1 
ATOM   12647 C CA  . ALA D 1 308 ? -48.788 -3.946  -29.286 1.00 36.23  ? 308 ALA D CA  1 
ATOM   12648 C C   . ALA D 1 308 ? -49.925 -4.965  -29.275 1.00 39.35  ? 308 ALA D C   1 
ATOM   12649 O O   . ALA D 1 308 ? -50.635 -5.098  -28.272 1.00 42.52  ? 308 ALA D O   1 
ATOM   12650 C CB  . ALA D 1 308 ? -49.159 -2.716  -30.118 1.00 33.34  ? 308 ALA D CB  1 
ATOM   12651 N N   . ALA D 1 309 ? -50.085 -5.685  -30.393 1.00 37.73  ? 309 ALA D N   1 
ATOM   12652 C CA  . ALA D 1 309 ? -51.153 -6.668  -30.531 1.00 40.73  ? 309 ALA D CA  1 
ATOM   12653 C C   . ALA D 1 309 ? -51.028 -7.768  -29.456 1.00 42.30  ? 309 ALA D C   1 
ATOM   12654 O O   . ALA D 1 309 ? -51.995 -8.072  -28.761 1.00 45.54  ? 309 ALA D O   1 
ATOM   12655 C CB  . ALA D 1 309 ? -51.127 -7.251  -31.918 1.00 43.68  ? 309 ALA D CB  1 
ATOM   12656 N N   . ARG D 1 310 ? -49.838 -8.360  -29.340 1.00 39.56  ? 310 ARG D N   1 
ATOM   12657 C CA  . ARG D 1 310 ? -49.606 -9.458  -28.412 1.00 42.01  ? 310 ARG D CA  1 
ATOM   12658 C C   . ARG D 1 310 ? -49.745 -8.963  -26.966 1.00 38.59  ? 310 ARG D C   1 
ATOM   12659 O O   . ARG D 1 310 ? -50.286 -9.659  -26.124 1.00 37.38  ? 310 ARG D O   1 
ATOM   12660 C CB  . ARG D 1 310 ? -48.216 -10.048 -28.682 1.00 52.10  ? 310 ARG D CB  1 
ATOM   12661 C CG  . ARG D 1 310 ? -47.894 -11.354 -27.966 1.00 67.87  ? 310 ARG D CG  1 
ATOM   12662 C CD  . ARG D 1 310 ? -48.593 -12.554 -28.579 1.00 73.34  ? 310 ARG D CD  1 
ATOM   12663 N NE  . ARG D 1 310 ? -49.733 -13.027 -27.774 1.00 84.11  ? 310 ARG D NE  1 
ATOM   12664 C CZ  . ARG D 1 310 ? -49.650 -13.885 -26.735 1.00 78.66  ? 310 ARG D CZ  1 
ATOM   12665 N NH1 . ARG D 1 310 ? -48.473 -14.336 -26.335 1.00 72.74  ? 310 ARG D NH1 1 
ATOM   12666 N NH2 . ARG D 1 310 ? -50.753 -14.297 -26.123 1.00 75.92  ? 310 ARG D NH2 1 
ATOM   12667 N N   . PHE D 1 311 ? -49.223 -7.761  -26.687 1.00 38.13  ? 311 PHE D N   1 
ATOM   12668 C CA  . PHE D 1 311 ? -49.278 -7.193  -25.342 1.00 35.34  ? 311 PHE D CA  1 
ATOM   12669 C C   . PHE D 1 311 ? -50.733 -7.010  -24.922 1.00 32.99  ? 311 PHE D C   1 
ATOM   12670 O O   . PHE D 1 311 ? -51.123 -7.438  -23.854 1.00 32.93  ? 311 PHE D O   1 
ATOM   12671 C CB  . PHE D 1 311 ? -48.510 -5.876  -25.291 1.00 37.29  ? 311 PHE D CB  1 
ATOM   12672 C CG  . PHE D 1 311 ? -48.378 -5.273  -23.905 1.00 34.71  ? 311 PHE D CG  1 
ATOM   12673 C CD1 . PHE D 1 311 ? -47.553 -5.850  -22.957 1.00 35.09  ? 311 PHE D CD1 1 
ATOM   12674 C CD2 . PHE D 1 311 ? -49.040 -4.101  -23.573 1.00 39.37  ? 311 PHE D CD2 1 
ATOM   12675 C CE1 . PHE D 1 311 ? -47.397 -5.284  -21.703 1.00 34.71  ? 311 PHE D CE1 1 
ATOM   12676 C CE2 . PHE D 1 311 ? -48.888 -3.529  -22.310 1.00 42.78  ? 311 PHE D CE2 1 
ATOM   12677 C CZ  . PHE D 1 311 ? -48.071 -4.130  -21.376 1.00 40.72  ? 311 PHE D CZ  1 
ATOM   12678 N N   . VAL D 1 312 ? -51.534 -6.394  -25.795 1.00 36.11  ? 312 VAL D N   1 
ATOM   12679 C CA  . VAL D 1 312 ? -52.941 -6.135  -25.514 1.00 33.53  ? 312 VAL D CA  1 
ATOM   12680 C C   . VAL D 1 312 ? -53.670 -7.456  -25.266 1.00 36.53  ? 312 VAL D C   1 
ATOM   12681 O O   . VAL D 1 312 ? -54.530 -7.538  -24.383 1.00 40.33  ? 312 VAL D O   1 
ATOM   12682 C CB  . VAL D 1 312 ? -53.597 -5.330  -26.649 1.00 33.98  ? 312 VAL D CB  1 
ATOM   12683 C CG1 . VAL D 1 312 ? -55.108 -5.521  -26.697 1.00 33.24  ? 312 VAL D CG1 1 
ATOM   12684 C CG2 . VAL D 1 312 ? -53.259 -3.853  -26.548 1.00 33.96  ? 312 VAL D CG2 1 
ATOM   12685 N N   . GLU D 1 313 ? -53.326 -8.485  -26.029 1.00 35.93  ? 313 GLU D N   1 
ATOM   12686 C CA  . GLU D 1 313 ? -54.008 -9.761  -25.916 1.00 40.84  ? 313 GLU D CA  1 
ATOM   12687 C C   . GLU D 1 313 ? -53.769 -10.358 -24.517 1.00 39.30  ? 313 GLU D C   1 
ATOM   12688 O O   . GLU D 1 313 ? -54.700 -10.845 -23.891 1.00 40.89  ? 313 GLU D O   1 
ATOM   12689 C CB  . GLU D 1 313 ? -53.560 -10.692 -27.032 1.00 51.19  ? 313 GLU D CB  1 
ATOM   12690 C CG  . GLU D 1 313 ? -54.587 -11.771 -27.386 1.00 66.83  ? 313 GLU D CG  1 
ATOM   12691 C CD  . GLU D 1 313 ? -54.051 -12.868 -28.327 1.00 79.69  ? 313 GLU D CD  1 
ATOM   12692 O OE1 . GLU D 1 313 ? -54.810 -13.310 -29.224 1.00 79.17  ? 313 GLU D OE1 1 
ATOM   12693 O OE2 . GLU D 1 313 ? -52.865 -13.272 -28.169 1.00 87.28  ? 313 GLU D OE2 1 
ATOM   12694 N N   . ARG D 1 314 ? -52.515 -10.334 -24.044 1.00 34.95  ? 314 ARG D N   1 
ATOM   12695 C CA  . ARG D 1 314 ? -52.194 -10.866 -22.722 1.00 37.61  ? 314 ARG D CA  1 
ATOM   12696 C C   . ARG D 1 314 ? -52.901 -10.047 -21.637 1.00 38.27  ? 314 ARG D C   1 
ATOM   12697 O O   . ARG D 1 314 ? -53.375 -10.613 -20.662 1.00 35.56  ? 314 ARG D O   1 
ATOM   12698 C CB  . ARG D 1 314 ? -50.693 -10.850 -22.437 1.00 40.03  ? 314 ARG D CB  1 
ATOM   12699 C CG  . ARG D 1 314 ? -49.903 -11.667 -23.436 1.00 52.53  ? 314 ARG D CG  1 
ATOM   12700 C CD  . ARG D 1 314 ? -49.890 -13.153 -23.069 1.00 55.85  ? 314 ARG D CD  1 
ATOM   12701 N NE  . ARG D 1 314 ? -49.169 -13.411 -21.815 1.00 64.78  ? 314 ARG D NE  1 
ATOM   12702 C CZ  . ARG D 1 314 ? -47.823 -13.388 -21.671 1.00 75.38  ? 314 ARG D CZ  1 
ATOM   12703 N NH1 . ARG D 1 314 ? -47.027 -13.232 -22.728 1.00 74.59  ? 314 ARG D NH1 1 
ATOM   12704 N NH2 . ARG D 1 314 ? -47.280 -13.539 -20.463 1.00 75.44  ? 314 ARG D NH2 1 
ATOM   12705 N N   . VAL D 1 315 ? -52.897 -8.693  -21.790 1.00 38.50  ? 315 VAL D N   1 
ATOM   12706 C CA  . VAL D 1 315 ? -53.382 -7.790  -20.750 1.00 35.67  ? 315 VAL D CA  1 
ATOM   12707 C C   . VAL D 1 315 ? -54.882 -8.035  -20.535 1.00 38.24  ? 315 VAL D C   1 
ATOM   12708 O O   . VAL D 1 315 ? -55.344 -8.057  -19.392 1.00 37.43  ? 315 VAL D O   1 
ATOM   12709 C CB  . VAL D 1 315 ? -53.087 -6.329  -21.113 1.00 36.08  ? 315 VAL D CB  1 
ATOM   12710 C CG1 . VAL D 1 315 ? -53.927 -5.353  -20.307 1.00 35.34  ? 315 VAL D CG1 1 
ATOM   12711 C CG2 . VAL D 1 315 ? -51.605 -6.004  -20.975 1.00 35.41  ? 315 VAL D CG2 1 
ATOM   12712 N N   . LYS D 1 316 ? -55.608 -8.314  -21.644 1.00 39.05  ? 316 LYS D N   1 
ATOM   12713 C CA  . LYS D 1 316 ? -57.029 -8.659  -21.600 1.00 42.08  ? 316 LYS D CA  1 
ATOM   12714 C C   . LYS D 1 316 ? -57.246 -9.908  -20.777 1.00 39.84  ? 316 LYS D C   1 
ATOM   12715 O O   . LYS D 1 316 ? -58.278 -10.066 -20.177 1.00 45.38  ? 316 LYS D O   1 
ATOM   12716 C CB  . LYS D 1 316 ? -57.618 -8.900  -22.994 1.00 45.92  ? 316 LYS D CB  1 
ATOM   12717 C CG  . LYS D 1 316 ? -57.778 -7.654  -23.802 1.00 55.08  ? 316 LYS D CG  1 
ATOM   12718 C CD  . LYS D 1 316 ? -58.778 -7.750  -24.942 1.00 65.98  ? 316 LYS D CD  1 
ATOM   12719 C CE  . LYS D 1 316 ? -58.125 -7.854  -26.313 1.00 71.40  ? 316 LYS D CE  1 
ATOM   12720 N NZ  . LYS D 1 316 ? -58.720 -6.888  -27.242 1.00 74.19  ? 316 LYS D NZ  1 
ATOM   12721 N N   . GLY D 1 317 ? -56.265 -10.791 -20.759 1.00 39.03  ? 317 GLY D N   1 
ATOM   12722 C CA  . GLY D 1 317 ? -56.390 -12.047 -20.037 1.00 37.54  ? 317 GLY D CA  1 
ATOM   12723 C C   . GLY D 1 317 ? -56.187 -11.876 -18.537 1.00 35.53  ? 317 GLY D C   1 
ATOM   12724 O O   . GLY D 1 317 ? -56.462 -12.793 -17.775 1.00 39.78  ? 317 GLY D O   1 
ATOM   12725 N N   . LEU D 1 318 ? -55.617 -10.741 -18.125 1.00 35.80  ? 318 LEU D N   1 
ATOM   12726 C CA  . LEU D 1 318 ? -55.227 -10.560 -16.724 1.00 35.22  ? 318 LEU D CA  1 
ATOM   12727 C C   . LEU D 1 318 ? -56.485 -10.511 -15.881 1.00 31.56  ? 318 LEU D C   1 
ATOM   12728 O O   . LEU D 1 318 ? -57.434 -9.865  -16.260 1.00 29.20  ? 318 LEU D O   1 
ATOM   12729 C CB  . LEU D 1 318 ? -54.411 -9.290  -16.545 1.00 36.14  ? 318 LEU D CB  1 
ATOM   12730 C CG  . LEU D 1 318 ? -53.018 -9.274  -17.177 1.00 34.37  ? 318 LEU D CG  1 
ATOM   12731 C CD1 . LEU D 1 318 ? -52.355 -7.907  -16.931 1.00 34.20  ? 318 LEU D CD1 1 
ATOM   12732 C CD2 . LEU D 1 318 ? -52.161 -10.388 -16.648 1.00 34.04  ? 318 LEU D CD2 1 
ATOM   12733 N N   . ARG D 1 319 ? -56.471 -11.216 -14.747 1.00 33.19  ? 319 ARG D N   1 
ATOM   12734 C CA  . ARG D 1 319 ? -57.653 -11.365 -13.902 1.00 36.24  ? 319 ARG D CA  1 
ATOM   12735 C C   . ARG D 1 319 ? -57.703 -10.243 -12.879 1.00 34.40  ? 319 ARG D C   1 
ATOM   12736 O O   . ARG D 1 319 ? -56.799 -10.108 -12.057 1.00 31.76  ? 319 ARG D O   1 
ATOM   12737 C CB  . ARG D 1 319 ? -57.661 -12.719 -13.186 1.00 40.87  ? 319 ARG D CB  1 
ATOM   12738 C CG  . ARG D 1 319 ? -58.458 -13.777 -13.952 1.00 47.95  ? 319 ARG D CG  1 
ATOM   12739 C CD  . ARG D 1 319 ? -58.056 -15.226 -13.636 1.00 56.48  ? 319 ARG D CD  1 
ATOM   12740 N NE  . ARG D 1 319 ? -58.663 -15.803 -12.418 1.00 63.15  ? 319 ARG D NE  1 
ATOM   12741 C CZ  . ARG D 1 319 ? -59.997 -15.911 -12.166 1.00 62.81  ? 319 ARG D CZ  1 
ATOM   12742 N NH1 . ARG D 1 319 ? -60.886 -15.333 -12.960 1.00 63.13  ? 319 ARG D NH1 1 
ATOM   12743 N NH2 . ARG D 1 319 ? -60.420 -16.551 -11.087 1.00 53.09  ? 319 ARG D NH2 1 
ATOM   12744 N N   . VAL D 1 320 ? -58.779 -9.450  -12.950 1.00 31.58  ? 320 VAL D N   1 
ATOM   12745 C CA  . VAL D 1 320 ? -59.064 -8.416  -11.971 1.00 34.04  ? 320 VAL D CA  1 
ATOM   12746 C C   . VAL D 1 320 ? -60.055 -8.967  -10.976 1.00 32.86  ? 320 VAL D C   1 
ATOM   12747 O O   . VAL D 1 320 ? -61.089 -9.451  -11.375 1.00 36.80  ? 320 VAL D O   1 
ATOM   12748 C CB  . VAL D 1 320 ? -59.643 -7.176  -12.684 1.00 33.68  ? 320 VAL D CB  1 
ATOM   12749 C CG1 . VAL D 1 320 ? -59.964 -6.047  -11.707 1.00 31.41  ? 320 VAL D CG1 1 
ATOM   12750 C CG2 . VAL D 1 320 ? -58.723 -6.695  -13.806 1.00 35.30  ? 320 VAL D CG2 1 
ATOM   12751 N N   . GLY D 1 321 ? -59.774 -8.841  -9.685  1.00 33.91  ? 321 GLY D N   1 
ATOM   12752 C CA  . GLY D 1 321 ? -60.768 -9.252  -8.690  1.00 35.17  ? 321 GLY D CA  1 
ATOM   12753 C C   . GLY D 1 321 ? -60.242 -9.190  -7.261  1.00 32.29  ? 321 GLY D C   1 
ATOM   12754 O O   . GLY D 1 321 ? -59.485 -8.326  -6.934  1.00 31.41  ? 321 GLY D O   1 
ATOM   12755 N N   . ASP D 1 322 ? -60.735 -10.097 -6.411  1.00 33.53  ? 322 ASP D N   1 
ATOM   12756 C CA  . ASP D 1 322 ? -60.480 -10.051 -4.986  1.00 30.66  ? 322 ASP D CA  1 
ATOM   12757 C C   . ASP D 1 322 ? -59.014 -10.380 -4.742  1.00 31.10  ? 322 ASP D C   1 
ATOM   12758 O O   . ASP D 1 322 ? -58.535 -11.454 -5.118  1.00 28.38  ? 322 ASP D O   1 
ATOM   12759 C CB  . ASP D 1 322 ? -61.427 -10.980 -4.247  1.00 33.74  ? 322 ASP D CB  1 
ATOM   12760 C CG  . ASP D 1 322 ? -61.037 -11.355 -2.823  1.00 35.13  ? 322 ASP D CG  1 
ATOM   12761 O OD1 . ASP D 1 322 ? -60.432 -10.515 -2.112  1.00 37.43  ? 322 ASP D OD1 1 
ATOM   12762 O OD2 . ASP D 1 322 ? -61.382 -12.434 -2.425  1.00 40.33  ? 322 ASP D OD2 1 
ATOM   12763 N N   . PRO D 1 323 ? -58.250 -9.471  -4.107  1.00 26.87  ? 323 PRO D N   1 
ATOM   12764 C CA  . PRO D 1 323 ? -56.820 -9.676  -3.937  1.00 28.88  ? 323 PRO D CA  1 
ATOM   12765 C C   . PRO D 1 323 ? -56.413 -10.871 -3.058  1.00 31.17  ? 323 PRO D C   1 
ATOM   12766 O O   . PRO D 1 323 ? -55.243 -11.262 -3.054  1.00 30.12  ? 323 PRO D O   1 
ATOM   12767 C CB  . PRO D 1 323 ? -56.382 -8.334  -3.310  1.00 26.94  ? 323 PRO D CB  1 
ATOM   12768 C CG  . PRO D 1 323 ? -57.625 -7.854  -2.594  1.00 25.04  ? 323 PRO D CG  1 
ATOM   12769 C CD  . PRO D 1 323 ? -58.727 -8.220  -3.502  1.00 24.71  ? 323 PRO D CD  1 
ATOM   12770 N N   . GLN D 1 324 ? -57.343 -11.390 -2.255  1.00 29.27  ? 324 GLN D N   1 
ATOM   12771 C CA  . GLN D 1 324 ? -57.030 -12.538 -1.404  1.00 32.32  ? 324 GLN D CA  1 
ATOM   12772 C C   . GLN D 1 324 ? -56.729 -13.783 -2.260  1.00 35.17  ? 324 GLN D C   1 
ATOM   12773 O O   . GLN D 1 324 ? -56.069 -14.702 -1.795  1.00 41.48  ? 324 GLN D O   1 
ATOM   12774 C CB  . GLN D 1 324 ? -58.178 -12.831 -0.457  1.00 31.66  ? 324 GLN D CB  1 
ATOM   12775 C CG  . GLN D 1 324 ? -58.270 -11.858 0.708   1.00 31.13  ? 324 GLN D CG  1 
ATOM   12776 C CD  . GLN D 1 324 ? -57.293 -12.168 1.813   1.00 31.39  ? 324 GLN D CD  1 
ATOM   12777 O OE1 . GLN D 1 324 ? -56.811 -13.304 1.956   1.00 36.43  ? 324 GLN D OE1 1 
ATOM   12778 N NE2 . GLN D 1 324 ? -56.995 -11.166 2.614   1.00 29.66  ? 324 GLN D NE2 1 
ATOM   12779 N N   . ARG D 1 325 ? -57.250 -13.824 -3.496  1.00 33.79  ? 325 ARG D N   1 
ATOM   12780 C CA  . ARG D 1 325 ? -57.065 -14.994 -4.349  1.00 33.92  ? 325 ARG D CA  1 
ATOM   12781 C C   . ARG D 1 325 ? -55.622 -15.027 -4.887  1.00 33.56  ? 325 ARG D C   1 
ATOM   12782 O O   . ARG D 1 325 ? -55.068 -14.010 -5.295  1.00 33.16  ? 325 ARG D O   1 
ATOM   12783 C CB  . ARG D 1 325 ? -58.072 -15.007 -5.511  1.00 30.25  ? 325 ARG D CB  1 
ATOM   12784 C CG  . ARG D 1 325 ? -59.526 -15.003 -5.070  1.00 31.44  ? 325 ARG D CG  1 
ATOM   12785 C CD  . ARG D 1 325 ? -60.505 -14.859 -6.250  1.00 29.42  ? 325 ARG D CD  1 
ATOM   12786 N NE  . ARG D 1 325 ? -60.226 -15.853 -7.279  1.00 31.54  ? 325 ARG D NE  1 
ATOM   12787 C CZ  . ARG D 1 325 ? -60.771 -17.061 -7.369  1.00 35.68  ? 325 ARG D CZ  1 
ATOM   12788 N NH1 . ARG D 1 325 ? -61.795 -17.377 -6.644  1.00 36.80  ? 325 ARG D NH1 1 
ATOM   12789 N NH2 . ARG D 1 325 ? -60.284 -17.951 -8.212  1.00 40.87  ? 325 ARG D NH2 1 
ATOM   12790 N N   . ALA D 1 326 ? -55.074 -16.231 -4.968  1.00 35.67  ? 326 ALA D N   1 
ATOM   12791 C CA  . ALA D 1 326 ? -53.754 -16.458 -5.540  1.00 34.05  ? 326 ALA D CA  1 
ATOM   12792 C C   . ALA D 1 326 ? -53.743 -16.201 -7.044  1.00 31.02  ? 326 ALA D C   1 
ATOM   12793 O O   . ALA D 1 326 ? -52.700 -15.973 -7.598  1.00 34.67  ? 326 ALA D O   1 
ATOM   12794 C CB  . ALA D 1 326 ? -53.294 -17.875 -5.229  1.00 31.94  ? 326 ALA D CB  1 
ATOM   12795 N N   . ASP D 1 327 ? -54.898 -16.273 -7.706  1.00 31.23  ? 327 ASP D N   1 
ATOM   12796 C CA  . ASP D 1 327 ? -54.927 -16.130 -9.169  1.00 31.55  ? 327 ASP D CA  1 
ATOM   12797 C C   . ASP D 1 327 ? -55.233 -14.679 -9.588  1.00 28.31  ? 327 ASP D C   1 
ATOM   12798 O O   . ASP D 1 327 ? -55.265 -14.368 -10.770 1.00 27.15  ? 327 ASP D O   1 
ATOM   12799 C CB  . ASP D 1 327 ? -55.900 -17.100 -9.810  1.00 37.45  ? 327 ASP D CB  1 
ATOM   12800 C CG  . ASP D 1 327 ? -57.373 -16.856 -9.512  1.00 41.26  ? 327 ASP D CG  1 
ATOM   12801 O OD1 . ASP D 1 327 ? -57.681 -15.879 -8.778  1.00 44.56  ? 327 ASP D OD1 1 
ATOM   12802 O OD2 . ASP D 1 327 ? -58.186 -17.638 -10.007 1.00 40.48  ? 327 ASP D OD2 1 
ATOM   12803 N N   . THR D 1 328 ? -55.431 -13.792 -8.627  1.00 29.73  ? 328 THR D N   1 
ATOM   12804 C CA  . THR D 1 328 ? -55.744 -12.409 -8.958  1.00 29.58  ? 328 THR D CA  1 
ATOM   12805 C C   . THR D 1 328 ? -54.459 -11.675 -9.424  1.00 33.51  ? 328 THR D C   1 
ATOM   12806 O O   . THR D 1 328 ? -53.477 -11.588 -8.695  1.00 32.73  ? 328 THR D O   1 
ATOM   12807 C CB  . THR D 1 328 ? -56.385 -11.710 -7.771  1.00 29.34  ? 328 THR D CB  1 
ATOM   12808 O OG1 . THR D 1 328 ? -57.714 -12.233 -7.589  1.00 29.49  ? 328 THR D OG1 1 
ATOM   12809 C CG2 . THR D 1 328 ? -56.446 -10.206 -7.990  1.00 28.25  ? 328 THR D CG2 1 
ATOM   12810 N N   . ALA D 1 329 ? -54.515 -11.082 -10.618 1.00 33.22  ? 329 ALA D N   1 
ATOM   12811 C CA  . ALA D 1 329 ? -53.395 -10.299 -11.153 1.00 32.96  ? 329 ALA D CA  1 
ATOM   12812 C C   . ALA D 1 329 ? -53.506 -8.809  -10.737 1.00 30.15  ? 329 ALA D C   1 
ATOM   12813 O O   . ALA D 1 329 ? -52.521 -8.186  -10.435 1.00 29.20  ? 329 ALA D O   1 
ATOM   12814 C CB  . ALA D 1 329 ? -53.345 -10.443 -12.677 1.00 32.35  ? 329 ALA D CB  1 
ATOM   12815 N N   . VAL D 1 330 ? -54.701 -8.239  -10.838 1.00 30.80  ? 330 VAL D N   1 
ATOM   12816 C CA  . VAL D 1 330 ? -54.910 -6.828  -10.544 1.00 31.60  ? 330 VAL D CA  1 
ATOM   12817 C C   . VAL D 1 330 ? -55.953 -6.718  -9.423  1.00 32.34  ? 330 VAL D C   1 
ATOM   12818 O O   . VAL D 1 330 ? -57.027 -7.322  -9.486  1.00 31.97  ? 330 VAL D O   1 
ATOM   12819 C CB  . VAL D 1 330 ? -55.339 -6.018  -11.795 1.00 31.73  ? 330 VAL D CB  1 
ATOM   12820 C CG1 . VAL D 1 330 ? -55.325 -4.548  -11.539 1.00 32.05  ? 330 VAL D CG1 1 
ATOM   12821 C CG2 . VAL D 1 330 ? -54.477 -6.320  -12.999 1.00 31.77  ? 330 VAL D CG2 1 
ATOM   12822 N N   . GLY D 1 331 ? -55.607 -5.961  -8.380  1.00 35.21  ? 331 GLY D N   1 
ATOM   12823 C CA  . GLY D 1 331 ? -56.497 -5.740  -7.242  1.00 30.36  ? 331 GLY D CA  1 
ATOM   12824 C C   . GLY D 1 331 ? -56.846 -4.258  -7.103  1.00 30.59  ? 331 GLY D C   1 
ATOM   12825 O O   . GLY D 1 331 ? -56.646 -3.469  -8.034  1.00 27.68  ? 331 GLY D O   1 
ATOM   12826 N N   . PRO D 1 332 ? -57.363 -3.830  -5.941  1.00 31.62  ? 332 PRO D N   1 
ATOM   12827 C CA  . PRO D 1 332 ? -57.838 -2.461  -5.780  1.00 32.68  ? 332 PRO D CA  1 
ATOM   12828 C C   . PRO D 1 332 ? -56.737 -1.433  -5.551  1.00 32.03  ? 332 PRO D C   1 
ATOM   12829 O O   . PRO D 1 332 ? -55.724 -1.730  -4.928  1.00 31.24  ? 332 PRO D O   1 
ATOM   12830 C CB  . PRO D 1 332 ? -58.758 -2.598  -4.571  1.00 32.99  ? 332 PRO D CB  1 
ATOM   12831 C CG  . PRO D 1 332 ? -58.096 -3.693  -3.727  1.00 30.79  ? 332 PRO D CG  1 
ATOM   12832 C CD  . PRO D 1 332 ? -57.555 -4.651  -4.746  1.00 30.69  ? 332 PRO D CD  1 
ATOM   12833 N N   . ILE D 1 333 ? -56.992 -0.208  -6.013  1.00 34.15  ? 333 ILE D N   1 
ATOM   12834 C CA  . ILE D 1 333 ? -56.208 0.965   -5.623  1.00 35.18  ? 333 ILE D CA  1 
ATOM   12835 C C   . ILE D 1 333 ? -56.452 1.269   -4.129  1.00 36.83  ? 333 ILE D C   1 
ATOM   12836 O O   . ILE D 1 333 ? -57.574 1.157   -3.640  1.00 34.81  ? 333 ILE D O   1 
ATOM   12837 C CB  . ILE D 1 333 ? -56.570 2.162   -6.519  1.00 32.08  ? 333 ILE D CB  1 
ATOM   12838 C CG1 . ILE D 1 333 ? -56.347 1.834   -7.979  1.00 32.08  ? 333 ILE D CG1 1 
ATOM   12839 C CG2 . ILE D 1 333 ? -55.801 3.410   -6.108  1.00 32.06  ? 333 ILE D CG2 1 
ATOM   12840 C CD1 . ILE D 1 333 ? -54.888 1.558   -8.329  1.00 31.09  ? 333 ILE D CD1 1 
ATOM   12841 N N   . VAL D 1 334 ? -55.401 1.732   -3.446  1.00 36.65  ? 334 VAL D N   1 
ATOM   12842 C CA  . VAL D 1 334 ? -55.367 1.756   -1.995  1.00 36.26  ? 334 VAL D CA  1 
ATOM   12843 C C   . VAL D 1 334 ? -56.393 2.774   -1.450  1.00 36.97  ? 334 VAL D C   1 
ATOM   12844 O O   . VAL D 1 334 ? -57.039 2.496   -0.463  1.00 37.67  ? 334 VAL D O   1 
ATOM   12845 C CB  . VAL D 1 334 ? -53.949 2.034   -1.452  1.00 39.05  ? 334 VAL D CB  1 
ATOM   12846 C CG1 . VAL D 1 334 ? -53.354 3.335   -1.999  1.00 38.93  ? 334 VAL D CG1 1 
ATOM   12847 C CG2 . VAL D 1 334 ? -53.931 2.053   0.070   1.00 44.16  ? 334 VAL D CG2 1 
ATOM   12848 N N   . ASN D 1 335 ? -56.509 3.961   -2.074  1.00 36.54  ? 335 ASN D N   1 
ATOM   12849 C CA  . ASN D 1 335 ? -57.448 4.978   -1.587  1.00 38.19  ? 335 ASN D CA  1 
ATOM   12850 C C   . ASN D 1 335 ? -58.086 5.756   -2.755  1.00 43.40  ? 335 ASN D C   1 
ATOM   12851 O O   . ASN D 1 335 ? -57.642 5.671   -3.914  1.00 37.31  ? 335 ASN D O   1 
ATOM   12852 C CB  . ASN D 1 335 ? -56.794 5.946   -0.590  1.00 36.94  ? 335 ASN D CB  1 
ATOM   12853 C CG  . ASN D 1 335 ? -55.643 6.709   -1.191  1.00 39.35  ? 335 ASN D CG  1 
ATOM   12854 O OD1 . ASN D 1 335 ? -55.738 7.208   -2.317  1.00 38.59  ? 335 ASN D OD1 1 
ATOM   12855 N ND2 . ASN D 1 335 ? -54.543 6.794   -0.469  1.00 42.93  ? 335 ASN D ND2 1 
ATOM   12856 N N   . ALA D 1 336 ? -59.100 6.578   -2.399  1.00 45.62  ? 336 ALA D N   1 
ATOM   12857 C CA  . ALA D 1 336 ? -59.888 7.355   -3.354  1.00 46.15  ? 336 ALA D CA  1 
ATOM   12858 C C   . ALA D 1 336 ? -59.019 8.401   -4.078  1.00 40.16  ? 336 ALA D C   1 
ATOM   12859 O O   . ALA D 1 336 ? -59.239 8.680   -5.241  1.00 39.39  ? 336 ALA D O   1 
ATOM   12860 C CB  . ALA D 1 336 ? -61.067 8.011   -2.633  1.00 41.01  ? 336 ALA D CB  1 
ATOM   12861 N N   . ARG D 1 337 ? -58.064 8.986   -3.372  1.00 41.70  ? 337 ARG D N   1 
ATOM   12862 C CA  . ARG D 1 337 ? -57.277 10.072  -3.922  1.00 43.54  ? 337 ARG D CA  1 
ATOM   12863 C C   . ARG D 1 337 ? -56.424 9.547   -5.080  1.00 45.86  ? 337 ARG D C   1 
ATOM   12864 O O   . ARG D 1 337 ? -56.413 10.131  -6.164  1.00 42.08  ? 337 ARG D O   1 
ATOM   12865 C CB  . ARG D 1 337 ? -56.392 10.706  -2.847  1.00 50.00  ? 337 ARG D CB  1 
ATOM   12866 C CG  . ARG D 1 337 ? -55.877 12.090  -3.205  1.00 50.00  ? 337 ARG D CG  1 
ATOM   12867 C CD  . ARG D 1 337 ? -54.959 12.701  -2.158  1.00 50.00  ? 337 ARG D CD  1 
ATOM   12868 N NE  . ARG D 1 337 ? -54.546 14.056  -2.514  1.00 50.00  ? 337 ARG D NE  1 
ATOM   12869 C CZ  . ARG D 1 337 ? -53.842 14.852  -1.723  1.00 50.00  ? 337 ARG D CZ  1 
ATOM   12870 N NH1 . ARG D 1 337 ? -53.462 14.432  -0.523  1.00 50.00  ? 337 ARG D NH1 1 
ATOM   12871 N NH2 . ARG D 1 337 ? -53.512 16.071  -2.130  1.00 50.00  ? 337 ARG D NH2 1 
ATOM   12872 N N   . GLN D 1 338 ? -55.724 8.429   -4.841  1.00 43.37  ? 338 GLN D N   1 
ATOM   12873 C CA  . GLN D 1 338 ? -54.903 7.807   -5.866  1.00 43.65  ? 338 GLN D CA  1 
ATOM   12874 C C   . GLN D 1 338 ? -55.773 7.388   -7.073  1.00 41.70  ? 338 GLN D C   1 
ATOM   12875 O O   . GLN D 1 338 ? -55.351 7.513   -8.210  1.00 39.73  ? 338 GLN D O   1 
ATOM   12876 C CB  . GLN D 1 338 ? -54.128 6.620   -5.296  1.00 40.72  ? 338 GLN D CB  1 
ATOM   12877 C CG  . GLN D 1 338 ? -53.029 7.012   -4.320  1.00 45.87  ? 338 GLN D CG  1 
ATOM   12878 C CD  . GLN D 1 338 ? -52.143 8.124   -4.848  1.00 58.04  ? 338 GLN D CD  1 
ATOM   12879 O OE1 . GLN D 1 338 ? -51.750 8.135   -6.024  1.00 68.15  ? 338 GLN D OE1 1 
ATOM   12880 N NE2 . GLN D 1 338 ? -51.834 9.085   -3.987  1.00 65.86  ? 338 GLN D NE2 1 
ATOM   12881 N N   . LEU D 1 339 ? -56.975 6.882   -6.808  1.00 41.86  ? 339 LEU D N   1 
ATOM   12882 C CA  . LEU D 1 339 ? -57.863 6.441   -7.870  1.00 40.69  ? 339 LEU D CA  1 
ATOM   12883 C C   . LEU D 1 339 ? -58.261 7.623   -8.741  1.00 39.43  ? 339 LEU D C   1 
ATOM   12884 O O   . LEU D 1 339 ? -58.240 7.526   -9.961  1.00 48.55  ? 339 LEU D O   1 
ATOM   12885 C CB  . LEU D 1 339 ? -59.096 5.756   -7.318  1.00 35.91  ? 339 LEU D CB  1 
ATOM   12886 C CG  . LEU D 1 339 ? -60.066 5.260   -8.382  1.00 39.46  ? 339 LEU D CG  1 
ATOM   12887 C CD1 . LEU D 1 339 ? -59.387 4.129   -9.229  1.00 37.44  ? 339 LEU D CD1 1 
ATOM   12888 C CD2 . LEU D 1 339 ? -61.393 4.789   -7.745  1.00 41.21  ? 339 LEU D CD2 1 
ATOM   12889 N N   . GLU D 1 340 ? -58.684 8.707   -8.101  1.00 41.65  ? 340 GLU D N   1 
ATOM   12890 C CA  . GLU D 1 340 ? -59.133 9.903   -8.807  1.00 44.31  ? 340 GLU D CA  1 
ATOM   12891 C C   . GLU D 1 340 ? -58.006 10.414  -9.717  1.00 42.37  ? 340 GLU D C   1 
ATOM   12892 O O   . GLU D 1 340 ? -58.273 10.840  -10.840 1.00 43.78  ? 340 GLU D O   1 
ATOM   12893 C CB  . GLU D 1 340 ? -59.602 10.982  -7.823  1.00 48.08  ? 340 GLU D CB  1 
ATOM   12894 C CG  . GLU D 1 340 ? -60.931 10.648  -7.138  1.00 62.01  ? 340 GLU D CG  1 
ATOM   12895 C CD  . GLU D 1 340 ? -61.238 11.387  -5.802  1.00 79.20  ? 340 GLU D CD  1 
ATOM   12896 O OE1 . GLU D 1 340 ? -62.373 11.187  -5.258  1.00 69.99  ? 340 GLU D OE1 1 
ATOM   12897 O OE2 . GLU D 1 340 ? -60.342 12.118  -5.274  1.00 88.39  ? 340 GLU D OE2 1 
ATOM   12898 N N   . GLY D 1 341 ? -56.747 10.348  -9.212  1.00 36.96  ? 341 GLY D N   1 
ATOM   12899 C CA  . GLY D 1 341 ? -55.560 10.763  -9.959  1.00 34.14  ? 341 GLY D CA  1 
ATOM   12900 C C   . GLY D 1 341 ? -55.361 9.925   -11.227 1.00 36.69  ? 341 GLY D C   1 
ATOM   12901 O O   . GLY D 1 341 ? -55.058 10.462  -12.283 1.00 38.61  ? 341 GLY D O   1 
ATOM   12902 N N   . LEU D 1 342 ? -55.555 8.603   -11.107 1.00 38.14  ? 342 LEU D N   1 
ATOM   12903 C CA  . LEU D 1 342 ? -55.338 7.691   -12.219 1.00 36.89  ? 342 LEU D CA  1 
ATOM   12904 C C   . LEU D 1 342 ? -56.441 7.875   -13.262 1.00 34.64  ? 342 LEU D C   1 
ATOM   12905 O O   . LEU D 1 342 ? -56.165 7.833   -14.455 1.00 37.49  ? 342 LEU D O   1 
ATOM   12906 C CB  . LEU D 1 342 ? -55.268 6.253   -11.732 1.00 35.51  ? 342 LEU D CB  1 
ATOM   12907 C CG  . LEU D 1 342 ? -53.990 5.849   -10.989 1.00 32.40  ? 342 LEU D CG  1 
ATOM   12908 C CD1 . LEU D 1 342 ? -54.286 4.648   -10.082 1.00 31.76  ? 342 LEU D CD1 1 
ATOM   12909 C CD2 . LEU D 1 342 ? -52.883 5.525   -11.950 1.00 32.89  ? 342 LEU D CD2 1 
ATOM   12910 N N   . LEU D 1 343 ? -57.673 8.110   -12.808 1.00 36.14  ? 343 LEU D N   1 
ATOM   12911 C CA  . LEU D 1 343 ? -58.800 8.357   -13.723 1.00 39.02  ? 343 LEU D CA  1 
ATOM   12912 C C   . LEU D 1 343 ? -58.560 9.660   -14.493 1.00 39.65  ? 343 LEU D C   1 
ATOM   12913 O O   . LEU D 1 343 ? -58.920 9.771   -15.653 1.00 38.97  ? 343 LEU D O   1 
ATOM   12914 C CB  . LEU D 1 343 ? -60.127 8.408   -12.958 1.00 37.53  ? 343 LEU D CB  1 
ATOM   12915 C CG  . LEU D 1 343 ? -60.681 7.064   -12.465 1.00 39.14  ? 343 LEU D CG  1 
ATOM   12916 C CD1 . LEU D 1 343 ? -61.948 7.282   -11.686 1.00 38.24  ? 343 LEU D CD1 1 
ATOM   12917 C CD2 . LEU D 1 343 ? -60.939 6.094   -13.613 1.00 38.59  ? 343 LEU D CD2 1 
ATOM   12918 N N   . GLU D 1 344 ? -57.945 10.635  -13.820 1.00 42.63  ? 344 GLU D N   1 
ATOM   12919 C CA  . GLU D 1 344 ? -57.639 11.911  -14.426 1.00 45.02  ? 344 GLU D CA  1 
ATOM   12920 C C   . GLU D 1 344 ? -56.559 11.710  -15.488 1.00 48.45  ? 344 GLU D C   1 
ATOM   12921 O O   . GLU D 1 344 ? -56.637 12.299  -16.560 1.00 51.28  ? 344 GLU D O   1 
ATOM   12922 C CB  . GLU D 1 344 ? -57.242 12.937  -13.351 1.00 49.16  ? 344 GLU D CB  1 
ATOM   12923 C CG  . GLU D 1 344 ? -56.579 14.192  -13.914 1.00 59.25  ? 344 GLU D CG  1 
ATOM   12924 C CD  . GLU D 1 344 ? -57.446 14.961  -14.906 1.00 74.36  ? 344 GLU D CD  1 
ATOM   12925 O OE1 . GLU D 1 344 ? -58.677 14.788  -14.870 1.00 79.81  ? 344 GLU D OE1 1 
ATOM   12926 O OE2 . GLU D 1 344 ? -56.885 15.716  -15.731 1.00 93.36  ? 344 GLU D OE2 1 
ATOM   12927 N N   . LYS D 1 345 ? -55.558 10.862  -15.191 1.00 39.86  ? 345 LYS D N   1 
ATOM   12928 C CA  . LYS D 1 345 ? -54.479 10.621  -16.145 1.00 44.19  ? 345 LYS D CA  1 
ATOM   12929 C C   . LYS D 1 345 ? -55.030 9.912   -17.378 1.00 41.55  ? 345 LYS D C   1 
ATOM   12930 O O   . LYS D 1 345 ? -54.610 10.191  -18.482 1.00 39.99  ? 345 LYS D O   1 
ATOM   12931 C CB  . LYS D 1 345 ? -53.331 9.813   -15.546 1.00 44.69  ? 345 LYS D CB  1 
ATOM   12932 C CG  . LYS D 1 345 ? -52.512 10.544  -14.526 1.00 43.10  ? 345 LYS D CG  1 
ATOM   12933 C CD  . LYS D 1 345 ? -51.535 9.639   -13.794 1.00 48.34  ? 345 LYS D CD  1 
ATOM   12934 C CE  . LYS D 1 345 ? -50.612 10.363  -12.863 1.00 54.38  ? 345 LYS D CE  1 
ATOM   12935 N NZ  . LYS D 1 345 ? -49.238 10.431  -13.394 1.00 62.66  ? 345 LYS D NZ  1 
ATOM   12936 N N   . ILE D 1 346 ? -55.988 9.009   -17.173 1.00 40.71  ? 346 ILE D N   1 
ATOM   12937 C CA  . ILE D 1 346 ? -56.648 8.342   -18.286 1.00 40.11  ? 346 ILE D CA  1 
ATOM   12938 C C   . ILE D 1 346 ? -57.341 9.381   -19.185 1.00 44.57  ? 346 ILE D C   1 
ATOM   12939 O O   . ILE D 1 346 ? -57.190 9.346   -20.400 1.00 44.45  ? 346 ILE D O   1 
ATOM   12940 C CB  . ILE D 1 346 ? -57.625 7.288   -17.787 1.00 35.28  ? 346 ILE D CB  1 
ATOM   12941 C CG1 . ILE D 1 346 ? -56.867 6.060   -17.223 1.00 40.83  ? 346 ILE D CG1 1 
ATOM   12942 C CG2 . ILE D 1 346 ? -58.604 6.893   -18.896 1.00 36.49  ? 346 ILE D CG2 1 
ATOM   12943 C CD1 . ILE D 1 346 ? -57.696 5.175   -16.289 1.00 39.57  ? 346 ILE D CD1 1 
ATOM   12944 N N   . ARG D 1 347 ? -58.082 10.309  -18.587 1.00 46.05  ? 347 ARG D N   1 
ATOM   12945 C CA  . ARG D 1 347 ? -58.814 11.296  -19.376 1.00 50.63  ? 347 ARG D CA  1 
ATOM   12946 C C   . ARG D 1 347 ? -57.822 12.266  -20.038 1.00 43.47  ? 347 ARG D C   1 
ATOM   12947 O O   . ARG D 1 347 ? -58.009 12.651  -21.167 1.00 39.85  ? 347 ARG D O   1 
ATOM   12948 C CB  . ARG D 1 347 ? -59.895 12.009  -18.556 1.00 59.63  ? 347 ARG D CB  1 
ATOM   12949 C CG  . ARG D 1 347 ? -59.513 13.332  -17.913 1.00 72.30  ? 347 ARG D CG  1 
ATOM   12950 C CD  . ARG D 1 347 ? -60.713 14.282  -17.943 1.00 80.29  ? 347 ARG D CD  1 
ATOM   12951 N NE  . ARG D 1 347 ? -60.430 15.620  -17.411 1.00 83.84  ? 347 ARG D NE  1 
ATOM   12952 C CZ  . ARG D 1 347 ? -59.598 16.519  -17.949 1.00 86.37  ? 347 ARG D CZ  1 
ATOM   12953 N NH1 . ARG D 1 347 ? -58.809 16.192  -18.963 1.00 74.14  ? 347 ARG D NH1 1 
ATOM   12954 N NH2 . ARG D 1 347 ? -59.542 17.743  -17.444 1.00 101.20 ? 347 ARG D NH2 1 
ATOM   12955 N N   . LEU D 1 348 ? -56.735 12.595  -19.341 1.00 44.15  ? 348 LEU D N   1 
ATOM   12956 C CA  . LEU D 1 348 ? -55.726 13.495  -19.888 1.00 42.03  ? 348 LEU D CA  1 
ATOM   12957 C C   . LEU D 1 348 ? -55.038 12.832  -21.086 1.00 44.53  ? 348 LEU D C   1 
ATOM   12958 O O   . LEU D 1 348 ? -54.688 13.501  -22.052 1.00 38.68  ? 348 LEU D O   1 
ATOM   12959 C CB  . LEU D 1 348 ? -54.710 13.875  -18.824 1.00 44.07  ? 348 LEU D CB  1 
ATOM   12960 C CG  . LEU D 1 348 ? -53.572 14.791  -19.289 1.00 49.81  ? 348 LEU D CG  1 
ATOM   12961 C CD1 . LEU D 1 348 ? -54.144 16.095  -19.884 1.00 50.94  ? 348 LEU D CD1 1 
ATOM   12962 C CD2 . LEU D 1 348 ? -52.595 15.094  -18.139 1.00 46.83  ? 348 LEU D CD2 1 
ATOM   12963 N N   . ALA D 1 349 ? -54.840 11.505  -21.007 1.00 47.95  ? 349 ALA D N   1 
ATOM   12964 C CA  . ALA D 1 349 ? -54.210 10.772  -22.090 1.00 48.44  ? 349 ALA D CA  1 
ATOM   12965 C C   . ALA D 1 349 ? -55.051 10.920  -23.349 1.00 48.30  ? 349 ALA D C   1 
ATOM   12966 O O   . ALA D 1 349 ? -54.509 11.128  -24.438 1.00 40.92  ? 349 ALA D O   1 
ATOM   12967 C CB  . ALA D 1 349 ? -54.018 9.338   -21.716 1.00 46.76  ? 349 ALA D CB  1 
ATOM   12968 N N   . ARG D 1 350 ? -56.383 10.883  -23.173 1.00 51.06  ? 350 ARG D N   1 
ATOM   12969 C CA  . ARG D 1 350 ? -57.299 10.913  -24.299 1.00 51.53  ? 350 ARG D CA  1 
ATOM   12970 C C   . ARG D 1 350 ? -57.209 12.274  -24.982 1.00 48.32  ? 350 ARG D C   1 
ATOM   12971 O O   . ARG D 1 350 ? -57.116 12.326  -26.193 1.00 48.74  ? 350 ARG D O   1 
ATOM   12972 C CB  . ARG D 1 350 ? -58.738 10.565  -23.905 1.00 50.81  ? 350 ARG D CB  1 
ATOM   12973 C CG  . ARG D 1 350 ? -59.309 9.464   -24.793 1.00 56.97  ? 350 ARG D CG  1 
ATOM   12974 C CD  . ARG D 1 350 ? -60.743 9.087   -24.473 1.00 61.03  ? 350 ARG D CD  1 
ATOM   12975 N NE  . ARG D 1 350 ? -61.011 9.135   -23.035 1.00 61.61  ? 350 ARG D NE  1 
ATOM   12976 C CZ  . ARG D 1 350 ? -60.954 8.099   -22.198 1.00 64.77  ? 350 ARG D CZ  1 
ATOM   12977 N NH1 . ARG D 1 350 ? -60.527 6.939   -22.617 1.00 60.15  ? 350 ARG D NH1 1 
ATOM   12978 N NH2 . ARG D 1 350 ? -61.303 8.252   -20.921 1.00 72.92  ? 350 ARG D NH2 1 
ATOM   12979 N N   . GLN D 1 351 ? -57.185 13.364  -24.191 1.00 47.80  ? 351 GLN D N   1 
ATOM   12980 C CA  . GLN D 1 351 ? -57.164 14.712  -24.751 1.00 52.77  ? 351 GLN D CA  1 
ATOM   12981 C C   . GLN D 1 351 ? -55.850 14.964  -25.483 1.00 49.06  ? 351 GLN D C   1 
ATOM   12982 O O   . GLN D 1 351 ? -55.834 15.735  -26.445 1.00 49.42  ? 351 GLN D O   1 
ATOM   12983 C CB  . GLN D 1 351 ? -57.236 15.860  -23.744 1.00 64.51  ? 351 GLN D CB  1 
ATOM   12984 C CG  . GLN D 1 351 ? -58.398 15.797  -22.775 1.00 79.68  ? 351 GLN D CG  1 
ATOM   12985 C CD  . GLN D 1 351 ? -58.596 17.109  -22.038 1.00 86.21  ? 351 GLN D CD  1 
ATOM   12986 O OE1 . GLN D 1 351 ? -57.715 17.990  -22.016 1.00 73.40  ? 351 GLN D OE1 1 
ATOM   12987 N NE2 . GLN D 1 351 ? -59.766 17.260  -21.446 1.00 92.21  ? 351 GLN D NE2 1 
ATOM   12988 N N   . GLU D 1 352 ? -54.737 14.395  -24.960 1.00 39.97  ? 352 GLU D N   1 
ATOM   12989 C CA  . GLU D 1 352 ? -53.424 14.632  -25.533 1.00 41.22  ? 352 GLU D CA  1 
ATOM   12990 C C   . GLU D 1 352 ? -53.261 13.810  -26.830 1.00 42.59  ? 352 GLU D C   1 
ATOM   12991 O O   . GLU D 1 352 ? -52.272 13.962  -27.533 1.00 52.67  ? 352 GLU D O   1 
ATOM   12992 C CB  . GLU D 1 352 ? -52.290 14.344  -24.549 1.00 44.86  ? 352 GLU D CB  1 
ATOM   12993 C CG  . GLU D 1 352 ? -52.340 15.210  -23.291 1.00 47.54  ? 352 GLU D CG  1 
ATOM   12994 C CD  . GLU D 1 352 ? -50.995 15.426  -22.567 1.00 47.56  ? 352 GLU D CD  1 
ATOM   12995 O OE1 . GLU D 1 352 ? -50.321 14.451  -22.167 1.00 49.98  ? 352 GLU D OE1 1 
ATOM   12996 O OE2 . GLU D 1 352 ? -50.654 16.591  -22.350 1.00 53.40  ? 352 GLU D OE2 1 
ATOM   12997 N N   . GLY D 1 353 ? -54.235 12.940  -27.128 1.00 40.11  ? 353 GLY D N   1 
ATOM   12998 C CA  . GLY D 1 353 ? -54.318 12.279  -28.424 1.00 45.89  ? 353 GLY D CA  1 
ATOM   12999 C C   . GLY D 1 353 ? -53.632 10.895  -28.444 1.00 47.15  ? 353 GLY D C   1 
ATOM   13000 O O   . GLY D 1 353 ? -53.362 10.354  -29.523 1.00 55.31  ? 353 GLY D O   1 
ATOM   13001 N N   . ALA D 1 354 ? -53.400 10.302  -27.267 1.00 39.81  ? 354 ALA D N   1 
ATOM   13002 C CA  . ALA D 1 354 ? -52.914 8.928   -27.196 1.00 36.31  ? 354 ALA D CA  1 
ATOM   13003 C C   . ALA D 1 354 ? -54.004 7.981   -27.686 1.00 35.16  ? 354 ALA D C   1 
ATOM   13004 O O   . ALA D 1 354 ? -55.179 8.190   -27.412 1.00 38.02  ? 354 ALA D O   1 
ATOM   13005 C CB  . ALA D 1 354 ? -52.481 8.589   -25.781 1.00 37.66  ? 354 ALA D CB  1 
ATOM   13006 N N   . LYS D 1 355 ? -53.602 6.936   -28.401 1.00 32.56  ? 355 LYS D N   1 
ATOM   13007 C CA  . LYS D 1 355 ? -54.550 6.026   -28.992 1.00 34.76  ? 355 LYS D CA  1 
ATOM   13008 C C   . LYS D 1 355 ? -54.915 4.940   -27.988 1.00 37.44  ? 355 LYS D C   1 
ATOM   13009 O O   . LYS D 1 355 ? -54.076 4.169   -27.593 1.00 38.61  ? 355 LYS D O   1 
ATOM   13010 C CB  . LYS D 1 355 ? -53.974 5.390   -30.246 1.00 33.11  ? 355 LYS D CB  1 
ATOM   13011 C CG  . LYS D 1 355 ? -54.964 4.608   -31.017 1.00 32.85  ? 355 LYS D CG  1 
ATOM   13012 C CD  . LYS D 1 355 ? -54.357 3.814   -32.145 1.00 38.23  ? 355 LYS D CD  1 
ATOM   13013 C CE  . LYS D 1 355 ? -55.321 2.854   -32.724 1.00 39.54  ? 355 LYS D CE  1 
ATOM   13014 N NZ  . LYS D 1 355 ? -54.640 2.009   -33.690 1.00 45.36  ? 355 LYS D NZ  1 
ATOM   13015 N N   . PRO D 1 356 ? -56.197 4.820   -27.586 1.00 43.70  ? 356 PRO D N   1 
ATOM   13016 C CA  . PRO D 1 356 ? -56.597 3.783   -26.637 1.00 42.67  ? 356 PRO D CA  1 
ATOM   13017 C C   . PRO D 1 356 ? -56.643 2.391   -27.260 1.00 41.77  ? 356 PRO D C   1 
ATOM   13018 O O   . PRO D 1 356 ? -57.449 2.118   -28.142 1.00 46.90  ? 356 PRO D O   1 
ATOM   13019 C CB  . PRO D 1 356 ? -58.000 4.270   -26.151 1.00 45.13  ? 356 PRO D CB  1 
ATOM   13020 C CG  . PRO D 1 356 ? -58.534 5.098   -27.325 1.00 41.15  ? 356 PRO D CG  1 
ATOM   13021 C CD  . PRO D 1 356 ? -57.302 5.730   -27.956 1.00 40.41  ? 356 PRO D CD  1 
ATOM   13022 N N   . LEU D 1 357 ? -55.801 1.501   -26.750 1.00 39.97  ? 357 LEU D N   1 
ATOM   13023 C CA  . LEU D 1 357 ? -55.724 0.148   -27.268 1.00 36.95  ? 357 LEU D CA  1 
ATOM   13024 C C   . LEU D 1 357 ? -56.612 -0.773  -26.442 1.00 34.32  ? 357 LEU D C   1 
ATOM   13025 O O   . LEU D 1 357 ? -57.237 -1.664  -26.990 1.00 32.07  ? 357 LEU D O   1 
ATOM   13026 C CB  . LEU D 1 357 ? -54.266 -0.328  -27.290 1.00 38.00  ? 357 LEU D CB  1 
ATOM   13027 C CG  . LEU D 1 357 ? -53.291 0.578   -28.067 1.00 38.17  ? 357 LEU D CG  1 
ATOM   13028 C CD1 . LEU D 1 357 ? -51.838 0.052   -28.018 1.00 40.12  ? 357 LEU D CD1 1 
ATOM   13029 C CD2 . LEU D 1 357 ? -53.763 0.735   -29.485 1.00 32.34  ? 357 LEU D CD2 1 
ATOM   13030 N N   . TYR D 1 358 ? -56.610 -0.602  -25.112 1.00 33.15  ? 358 TYR D N   1 
ATOM   13031 C CA  . TYR D 1 358 ? -57.470 -1.412  -24.246 1.00 34.28  ? 358 TYR D CA  1 
ATOM   13032 C C   . TYR D 1 358 ? -57.861 -0.613  -23.019 1.00 33.39  ? 358 TYR D C   1 
ATOM   13033 O O   . TYR D 1 358 ? -57.006 -0.034  -22.360 1.00 33.49  ? 358 TYR D O   1 
ATOM   13034 C CB  . TYR D 1 358 ? -56.805 -2.700  -23.784 1.00 36.49  ? 358 TYR D CB  1 
ATOM   13035 C CG  . TYR D 1 358 ? -57.689 -3.520  -22.871 1.00 37.57  ? 358 TYR D CG  1 
ATOM   13036 C CD1 . TYR D 1 358 ? -58.822 -4.155  -23.361 1.00 40.67  ? 358 TYR D CD1 1 
ATOM   13037 C CD2 . TYR D 1 358 ? -57.401 -3.655  -21.512 1.00 38.30  ? 358 TYR D CD2 1 
ATOM   13038 C CE1 . TYR D 1 358 ? -59.656 -4.896  -22.529 1.00 40.92  ? 358 TYR D CE1 1 
ATOM   13039 C CE2 . TYR D 1 358 ? -58.206 -4.416  -20.677 1.00 37.75  ? 358 TYR D CE2 1 
ATOM   13040 C CZ  . TYR D 1 358 ? -59.350 -5.023  -21.185 1.00 39.04  ? 358 TYR D CZ  1 
ATOM   13041 O OH  . TYR D 1 358 ? -60.168 -5.759  -20.383 1.00 41.04  ? 358 TYR D OH  1 
ATOM   13042 N N   . GLU D 1 359 ? -59.164 -0.604  -22.712 1.00 34.54  ? 359 GLU D N   1 
ATOM   13043 C CA  . GLU D 1 359 ? -59.683 0.142   -21.560 1.00 41.30  ? 359 GLU D CA  1 
ATOM   13044 C C   . GLU D 1 359 ? -60.636 -0.743  -20.772 1.00 38.99  ? 359 GLU D C   1 
ATOM   13045 O O   . GLU D 1 359 ? -61.748 -0.988  -21.213 1.00 38.00  ? 359 GLU D O   1 
ATOM   13046 C CB  . GLU D 1 359 ? -60.411 1.429   -21.968 1.00 39.72  ? 359 GLU D CB  1 
ATOM   13047 C CG  . GLU D 1 359 ? -59.527 2.404   -22.728 1.00 45.12  ? 359 GLU D CG  1 
ATOM   13048 C CD  . GLU D 1 359 ? -59.939 3.856   -22.609 1.00 46.68  ? 359 GLU D CD  1 
ATOM   13049 O OE1 . GLU D 1 359 ? -59.565 4.510   -21.607 1.00 52.22  ? 359 GLU D OE1 1 
ATOM   13050 O OE2 . GLU D 1 359 ? -60.649 4.325   -23.505 1.00 44.27  ? 359 GLU D OE2 1 
ATOM   13051 N N   . GLY D 1 360 ? -60.183 -1.189  -19.583 1.00 44.30  ? 360 GLY D N   1 
ATOM   13052 C CA  . GLY D 1 360 ? -60.976 -2.048  -18.703 1.00 43.87  ? 360 GLY D CA  1 
ATOM   13053 C C   . GLY D 1 360 ? -61.879 -1.212  -17.803 1.00 49.71  ? 360 GLY D C   1 
ATOM   13054 O O   . GLY D 1 360 ? -61.632 -0.018  -17.577 1.00 53.20  ? 360 GLY D O   1 
ATOM   13055 N N   . GLY D 1 361 ? -62.943 -1.811  -17.326 1.00 56.53  ? 361 GLY D N   1 
ATOM   13056 C CA  . GLY D 1 361 ? -63.921 -1.048  -16.550 1.00 78.44  ? 361 GLY D CA  1 
ATOM   13057 C C   . GLY D 1 361 ? -63.409 -0.764  -15.136 1.00 71.61  ? 361 GLY D C   1 
ATOM   13058 O O   . GLY D 1 361 ? -62.868 -1.668  -14.501 1.00 103.19 ? 361 GLY D O   1 
ATOM   13059 N N   . VAL D 1 362 ? -63.556 0.510   -14.667 1.00 51.89  ? 362 VAL D N   1 
ATOM   13060 C CA  . VAL D 1 362 ? -63.384 0.844   -13.252 1.00 42.62  ? 362 VAL D CA  1 
ATOM   13061 C C   . VAL D 1 362 ? -64.604 0.344   -12.488 1.00 42.47  ? 362 VAL D C   1 
ATOM   13062 O O   . VAL D 1 362 ? -65.725 0.618   -12.870 1.00 46.37  ? 362 VAL D O   1 
ATOM   13063 C CB  . VAL D 1 362 ? -63.145 2.339   -12.975 1.00 38.41  ? 362 VAL D CB  1 
ATOM   13064 C CG1 . VAL D 1 362 ? -64.319 3.208   -13.377 1.00 38.29  ? 362 VAL D CG1 1 
ATOM   13065 C CG2 . VAL D 1 362 ? -62.815 2.583   -11.533 1.00 39.18  ? 362 VAL D CG2 1 
ATOM   13066 N N   . ASP D 1 363 ? -64.349 -0.454  -11.444 1.00 47.82  ? 363 ASP D N   1 
ATOM   13067 C CA  . ASP D 1 363 ? -65.392 -1.020  -10.604 1.00 49.19  ? 363 ASP D CA  1 
ATOM   13068 C C   . ASP D 1 363 ? -65.019 -0.761  -9.136  1.00 44.96  ? 363 ASP D C   1 
ATOM   13069 O O   . ASP D 1 363 ? -64.248 -1.502  -8.543  1.00 45.36  ? 363 ASP D O   1 
ATOM   13070 C CB  . ASP D 1 363 ? -65.613 -2.492  -10.944 1.00 50.46  ? 363 ASP D CB  1 
ATOM   13071 C CG  . ASP D 1 363 ? -66.412 -3.300  -9.931  1.00 60.88  ? 363 ASP D CG  1 
ATOM   13072 O OD1 . ASP D 1 363 ? -66.167 -4.525  -9.832  1.00 63.34  ? 363 ASP D OD1 1 
ATOM   13073 O OD2 . ASP D 1 363 ? -67.260 -2.700  -9.234  1.00 70.13  ? 363 ASP D OD2 1 
ATOM   13074 N N   . GLY D 1 364 ? -65.543 0.330   -8.581  1.00 42.37  ? 364 GLY D N   1 
ATOM   13075 C CA  . GLY D 1 364 ? -65.157 0.786   -7.255  1.00 39.32  ? 364 GLY D CA  1 
ATOM   13076 C C   . GLY D 1 364 ? -63.671 1.147   -7.205  1.00 42.08  ? 364 GLY D C   1 
ATOM   13077 O O   . GLY D 1 364 ? -63.191 1.905   -8.046  1.00 41.89  ? 364 GLY D O   1 
ATOM   13078 N N   . GLN D 1 365 ? -62.935 0.550   -6.236  1.00 37.88  ? 365 GLN D N   1 
ATOM   13079 C CA  . GLN D 1 365 ? -61.491 0.720   -6.149  1.00 36.72  ? 365 GLN D CA  1 
ATOM   13080 C C   . GLN D 1 365 ? -60.754 -0.175  -7.180  1.00 35.34  ? 365 GLN D C   1 
ATOM   13081 O O   . GLN D 1 365 ? -59.580 -0.003  -7.398  1.00 38.60  ? 365 GLN D O   1 
ATOM   13082 C CB  . GLN D 1 365 ? -61.007 0.428   -4.730  1.00 40.23  ? 365 GLN D CB  1 
ATOM   13083 C CG  . GLN D 1 365 ? -61.459 1.457   -3.686  1.00 39.87  ? 365 GLN D CG  1 
ATOM   13084 C CD  . GLN D 1 365 ? -60.989 2.869   -3.986  1.00 43.38  ? 365 GLN D CD  1 
ATOM   13085 O OE1 . GLN D 1 365 ? -61.784 3.799   -4.060  1.00 48.63  ? 365 GLN D OE1 1 
ATOM   13086 N NE2 . GLN D 1 365 ? -59.682 3.040   -4.162  1.00 44.08  ? 365 GLN D NE2 1 
ATOM   13087 N N   . LEU D 1 366 ? -61.441 -1.129  -7.796  1.00 34.36  ? 366 LEU D N   1 
ATOM   13088 C CA  . LEU D 1 366 ? -60.804 -1.965  -8.813  1.00 36.73  ? 366 LEU D CA  1 
ATOM   13089 C C   . LEU D 1 366 ? -60.690 -1.172  -10.101 1.00 39.14  ? 366 LEU D C   1 
ATOM   13090 O O   . LEU D 1 366 ? -61.666 -1.055  -10.825 1.00 36.94  ? 366 LEU D O   1 
ATOM   13091 C CB  . LEU D 1 366 ? -61.578 -3.260  -9.077  1.00 34.86  ? 366 LEU D CB  1 
ATOM   13092 C CG  . LEU D 1 366 ? -61.572 -4.301  -7.955  1.00 37.79  ? 366 LEU D CG  1 
ATOM   13093 C CD1 . LEU D 1 366 ? -62.627 -5.358  -8.252  1.00 38.34  ? 366 LEU D CD1 1 
ATOM   13094 C CD2 . LEU D 1 366 ? -60.214 -4.946  -7.759  1.00 35.51  ? 366 LEU D CD2 1 
ATOM   13095 N N   . LEU D 1 367 ? -59.469 -0.722  -10.425 1.00 38.13  ? 367 LEU D N   1 
ATOM   13096 C CA  . LEU D 1 367 ? -59.176 -0.125  -11.724 1.00 37.27  ? 367 LEU D CA  1 
ATOM   13097 C C   . LEU D 1 367 ? -58.498 -1.167  -12.629 1.00 32.64  ? 367 LEU D C   1 
ATOM   13098 O O   . LEU D 1 367 ? -57.417 -1.631  -12.329 1.00 35.15  ? 367 LEU D O   1 
ATOM   13099 C CB  . LEU D 1 367 ? -58.286 1.085   -11.503 1.00 35.83  ? 367 LEU D CB  1 
ATOM   13100 C CG  . LEU D 1 367 ? -57.845 1.823   -12.763 1.00 37.01  ? 367 LEU D CG  1 
ATOM   13101 C CD1 . LEU D 1 367 ? -59.018 2.574   -13.423 1.00 34.10  ? 367 LEU D CD1 1 
ATOM   13102 C CD2 . LEU D 1 367 ? -56.702 2.777   -12.437 1.00 40.17  ? 367 LEU D CD2 1 
ATOM   13103 N N   . ALA D 1 368 ? -59.191 -1.568  -13.695 1.00 34.09  ? 368 ALA D N   1 
ATOM   13104 C CA  . ALA D 1 368 ? -58.697 -2.599  -14.601 1.00 34.34  ? 368 ALA D CA  1 
ATOM   13105 C C   . ALA D 1 368 ? -57.576 -2.005  -15.455 1.00 32.83  ? 368 ALA D C   1 
ATOM   13106 O O   . ALA D 1 368 ? -57.374 -0.802  -15.438 1.00 34.86  ? 368 ALA D O   1 
ATOM   13107 C CB  . ALA D 1 368 ? -59.831 -3.110  -15.432 1.00 31.17  ? 368 ALA D CB  1 
ATOM   13108 N N   . PRO D 1 369 ? -56.780 -2.813  -16.182 1.00 32.97  ? 369 PRO D N   1 
ATOM   13109 C CA  . PRO D 1 369 ? -55.700 -2.265  -17.008 1.00 35.29  ? 369 PRO D CA  1 
ATOM   13110 C C   . PRO D 1 369 ? -56.189 -1.294  -18.075 1.00 34.31  ? 369 PRO D C   1 
ATOM   13111 O O   . PRO D 1 369 ? -57.246 -1.495  -18.663 1.00 33.35  ? 369 PRO D O   1 
ATOM   13112 C CB  . PRO D 1 369 ? -55.042 -3.500  -17.613 1.00 33.44  ? 369 PRO D CB  1 
ATOM   13113 C CG  . PRO D 1 369 ? -55.412 -4.616  -16.652 1.00 33.73  ? 369 PRO D CG  1 
ATOM   13114 C CD  . PRO D 1 369 ? -56.795 -4.266  -16.167 1.00 34.51  ? 369 PRO D CD  1 
ATOM   13115 N N   . HIS D 1 370 ? -55.410 -0.224  -18.283 1.00 34.10  ? 370 HIS D N   1 
ATOM   13116 C CA  . HIS D 1 370 ? -55.614 0.703   -19.391 1.00 33.04  ? 370 HIS D CA  1 
ATOM   13117 C C   . HIS D 1 370 ? -54.305 0.838   -20.170 1.00 30.51  ? 370 HIS D C   1 
ATOM   13118 O O   . HIS D 1 370 ? -53.289 1.250   -19.612 1.00 31.28  ? 370 HIS D O   1 
ATOM   13119 C CB  . HIS D 1 370 ? -56.098 2.067   -18.867 1.00 34.06  ? 370 HIS D CB  1 
ATOM   13120 C CG  . HIS D 1 370 ? -57.504 2.048   -18.349 1.00 37.57  ? 370 HIS D CG  1 
ATOM   13121 N ND1 . HIS D 1 370 ? -57.833 1.551   -17.109 1.00 38.98  ? 370 HIS D ND1 1 
ATOM   13122 C CD2 . HIS D 1 370 ? -58.683 2.450   -18.916 1.00 37.58  ? 370 HIS D CD2 1 
ATOM   13123 C CE1 . HIS D 1 370 ? -59.145 1.625   -16.939 1.00 39.68  ? 370 HIS D CE1 1 
ATOM   13124 N NE2 . HIS D 1 370 ? -59.684 2.169   -18.030 1.00 36.59  ? 370 HIS D NE2 1 
ATOM   13125 N N   . VAL D 1 371 ? -54.352 0.507   -21.463 1.00 32.90  ? 371 VAL D N   1 
ATOM   13126 C CA  . VAL D 1 371 ? -53.191 0.592   -22.358 1.00 31.29  ? 371 VAL D CA  1 
ATOM   13127 C C   . VAL D 1 371 ? -53.452 1.637   -23.450 1.00 32.71  ? 371 VAL D C   1 
ATOM   13128 O O   . VAL D 1 371 ? -54.432 1.556   -24.180 1.00 34.18  ? 371 VAL D O   1 
ATOM   13129 C CB  . VAL D 1 371 ? -52.906 -0.787  -22.980 1.00 32.40  ? 371 VAL D CB  1 
ATOM   13130 C CG1 . VAL D 1 371 ? -51.716 -0.750  -23.950 1.00 34.69  ? 371 VAL D CG1 1 
ATOM   13131 C CG2 . VAL D 1 371 ? -52.688 -1.843  -21.904 1.00 31.92  ? 371 VAL D CG2 1 
ATOM   13132 N N   . PHE D 1 372 ? -52.504 2.549   -23.626 1.00 37.44  ? 372 PHE D N   1 
ATOM   13133 C CA  . PHE D 1 372 ? -52.564 3.527   -24.707 1.00 34.67  ? 372 PHE D CA  1 
ATOM   13134 C C   . PHE D 1 372 ? -51.402 3.300   -25.658 1.00 32.52  ? 372 PHE D C   1 
ATOM   13135 O O   . PHE D 1 372 ? -50.337 2.831   -25.244 1.00 31.68  ? 372 PHE D O   1 
ATOM   13136 C CB  . PHE D 1 372 ? -52.531 4.950   -24.132 1.00 35.90  ? 372 PHE D CB  1 
ATOM   13137 C CG  . PHE D 1 372 ? -53.866 5.392   -23.558 1.00 40.71  ? 372 PHE D CG  1 
ATOM   13138 C CD1 . PHE D 1 372 ? -54.221 5.088   -22.242 1.00 40.49  ? 372 PHE D CD1 1 
ATOM   13139 C CD2 . PHE D 1 372 ? -54.785 6.078   -24.347 1.00 40.31  ? 372 PHE D CD2 1 
ATOM   13140 C CE1 . PHE D 1 372 ? -55.457 5.479   -21.729 1.00 39.29  ? 372 PHE D CE1 1 
ATOM   13141 C CE2 . PHE D 1 372 ? -56.020 6.448   -23.835 1.00 43.32  ? 372 PHE D CE2 1 
ATOM   13142 C CZ  . PHE D 1 372 ? -56.342 6.168   -22.517 1.00 39.39  ? 372 PHE D CZ  1 
ATOM   13143 N N   . GLY D 1 373 ? -51.605 3.703   -26.925 1.00 33.50  ? 373 GLY D N   1 
ATOM   13144 C CA  . GLY D 1 373 ? -50.599 3.596   -27.970 1.00 32.87  ? 373 GLY D CA  1 
ATOM   13145 C C   . GLY D 1 373 ? -50.293 4.965   -28.613 1.00 36.30  ? 373 GLY D C   1 
ATOM   13146 O O   . GLY D 1 373 ? -50.903 5.974   -28.268 1.00 39.75  ? 373 GLY D O   1 
ATOM   13147 N N   . GLU D 1 374 ? -49.311 4.969   -29.538 1.00 34.65  ? 374 GLU D N   1 
ATOM   13148 C CA  . GLU D 1 374 ? -48.893 6.159   -30.279 1.00 31.53  ? 374 GLU D CA  1 
ATOM   13149 C C   . GLU D 1 374 ? -48.459 7.274   -29.324 1.00 33.54  ? 374 GLU D C   1 
ATOM   13150 O O   . GLU D 1 374 ? -48.619 8.447   -29.617 1.00 38.06  ? 374 GLU D O   1 
ATOM   13151 C CB  . GLU D 1 374 ? -50.012 6.664   -31.201 1.00 31.29  ? 374 GLU D CB  1 
ATOM   13152 C CG  . GLU D 1 374 ? -50.633 5.577   -32.084 1.00 30.60  ? 374 GLU D CG  1 
ATOM   13153 C CD  . GLU D 1 374 ? -49.700 4.922   -33.084 1.00 31.36  ? 374 GLU D CD  1 
ATOM   13154 O OE1 . GLU D 1 374 ? -48.768 5.630   -33.570 1.00 30.23  ? 374 GLU D OE1 1 
ATOM   13155 O OE2 . GLU D 1 374 ? -49.930 3.706   -33.432 1.00 32.81  ? 374 GLU D OE2 1 
ATOM   13156 N N   . VAL D 1 375 ? -47.851 6.913   -28.211 1.00 36.26  ? 375 VAL D N   1 
ATOM   13157 C CA  . VAL D 1 375 ? -47.492 7.899   -27.217 1.00 34.88  ? 375 VAL D CA  1 
ATOM   13158 C C   . VAL D 1 375 ? -46.219 8.605   -27.668 1.00 35.62  ? 375 VAL D C   1 
ATOM   13159 O O   . VAL D 1 375 ? -45.432 8.038   -28.394 1.00 34.77  ? 375 VAL D O   1 
ATOM   13160 C CB  . VAL D 1 375 ? -47.323 7.260   -25.832 1.00 37.03  ? 375 VAL D CB  1 
ATOM   13161 C CG1 . VAL D 1 375 ? -46.776 8.265   -24.801 1.00 36.20  ? 375 VAL D CG1 1 
ATOM   13162 C CG2 . VAL D 1 375 ? -48.623 6.634   -25.344 1.00 33.51  ? 375 VAL D CG2 1 
ATOM   13163 N N   . THR D 1 376 ? -46.059 9.878   -27.246 1.00 39.99  ? 376 THR D N   1 
ATOM   13164 C CA  . THR D 1 376 ? -44.839 10.647  -27.503 1.00 37.53  ? 376 THR D CA  1 
ATOM   13165 C C   . THR D 1 376 ? -44.262 11.160  -26.180 1.00 37.28  ? 376 THR D C   1 
ATOM   13166 O O   . THR D 1 376 ? -44.948 11.202  -25.155 1.00 36.17  ? 376 THR D O   1 
ATOM   13167 C CB  . THR D 1 376 ? -45.134 11.806  -28.459 1.00 38.72  ? 376 THR D CB  1 
ATOM   13168 O OG1 . THR D 1 376 ? -46.052 12.660  -27.771 1.00 42.14  ? 376 THR D OG1 1 
ATOM   13169 C CG2 . THR D 1 376 ? -45.706 11.331  -29.783 1.00 38.73  ? 376 THR D CG2 1 
ATOM   13170 N N   . ALA D 1 377 ? -43.028 11.642  -26.254 1.00 37.35  ? 377 ALA D N   1 
ATOM   13171 C CA  . ALA D 1 377 ? -42.234 11.965  -25.086 1.00 40.43  ? 377 ALA D CA  1 
ATOM   13172 C C   . ALA D 1 377 ? -42.848 13.113  -24.284 1.00 40.24  ? 377 ALA D C   1 
ATOM   13173 O O   . ALA D 1 377 ? -42.650 13.183  -23.062 1.00 44.67  ? 377 ALA D O   1 
ATOM   13174 C CB  . ALA D 1 377 ? -40.836 12.287  -25.510 1.00 41.81  ? 377 ALA D CB  1 
ATOM   13175 N N   . THR D 1 378 ? -43.609 13.999  -24.958 1.00 38.34  ? 378 THR D N   1 
ATOM   13176 C CA  . THR D 1 378 ? -44.135 15.209  -24.308 1.00 39.01  ? 378 THR D CA  1 
ATOM   13177 C C   . THR D 1 378 ? -45.414 14.898  -23.517 1.00 39.98  ? 378 THR D C   1 
ATOM   13178 O O   . THR D 1 378 ? -45.815 15.699  -22.684 1.00 42.83  ? 378 THR D O   1 
ATOM   13179 C CB  . THR D 1 378 ? -44.386 16.310  -25.333 1.00 37.59  ? 378 THR D CB  1 
ATOM   13180 O OG1 . THR D 1 378 ? -45.115 15.723  -26.403 1.00 43.31  ? 378 THR D OG1 1 
ATOM   13181 C CG2 . THR D 1 378 ? -43.104 16.875  -25.887 1.00 40.89  ? 378 THR D CG2 1 
ATOM   13182 N N   . MET D 1 379 ? -46.077 13.764  -23.800 1.00 36.87  ? 379 MET D N   1 
ATOM   13183 C CA  . MET D 1 379 ? -47.361 13.477  -23.148 1.00 38.14  ? 379 MET D CA  1 
ATOM   13184 C C   . MET D 1 379 ? -47.130 13.183  -21.663 1.00 41.65  ? 379 MET D C   1 
ATOM   13185 O O   . MET D 1 379 ? -46.066 12.700  -21.268 1.00 41.85  ? 379 MET D O   1 
ATOM   13186 C CB  . MET D 1 379 ? -48.090 12.298  -23.802 1.00 42.19  ? 379 MET D CB  1 
ATOM   13187 C CG  . MET D 1 379 ? -48.488 12.555  -25.233 1.00 41.43  ? 379 MET D CG  1 
ATOM   13188 S SD  . MET D 1 379 ? -49.168 11.105  -26.036 1.00 40.35  ? 379 MET D SD  1 
ATOM   13189 C CE  . MET D 1 379 ? -49.624 11.831  -27.611 1.00 39.78  ? 379 MET D CE  1 
ATOM   13190 N N   . GLU D 1 380 ? -48.124 13.508  -20.843 1.00 41.33  ? 380 GLU D N   1 
ATOM   13191 C CA  . GLU D 1 380 ? -47.989 13.378  -19.400 1.00 41.71  ? 380 GLU D CA  1 
ATOM   13192 C C   . GLU D 1 380 ? -47.807 11.897  -19.022 1.00 36.50  ? 380 GLU D C   1 
ATOM   13193 O O   . GLU D 1 380 ? -47.072 11.575  -18.092 1.00 35.56  ? 380 GLU D O   1 
ATOM   13194 C CB  . GLU D 1 380 ? -49.192 14.017  -18.698 1.00 49.89  ? 380 GLU D CB  1 
ATOM   13195 C CG  . GLU D 1 380 ? -49.073 14.048  -17.165 1.00 54.98  ? 380 GLU D CG  1 
ATOM   13196 C CD  . GLU D 1 380 ? -49.852 12.952  -16.437 1.00 57.62  ? 380 GLU D CD  1 
ATOM   13197 O OE1 . GLU D 1 380 ? -50.660 12.251  -17.087 1.00 61.81  ? 380 GLU D OE1 1 
ATOM   13198 O OE2 . GLU D 1 380 ? -49.646 12.793  -15.216 1.00 64.97  ? 380 GLU D OE2 1 
ATOM   13199 N N   . ILE D 1 381 ? -48.453 11.005  -19.770 1.00 35.62  ? 381 ILE D N   1 
ATOM   13200 C CA  . ILE D 1 381 ? -48.354 9.577   -19.507 1.00 36.34  ? 381 ILE D CA  1 
ATOM   13201 C C   . ILE D 1 381 ? -46.898 9.101   -19.692 1.00 40.59  ? 381 ILE D C   1 
ATOM   13202 O O   . ILE D 1 381 ? -46.465 8.159   -19.034 1.00 46.42  ? 381 ILE D O   1 
ATOM   13203 C CB  . ILE D 1 381 ? -49.347 8.794   -20.375 1.00 37.68  ? 381 ILE D CB  1 
ATOM   13204 C CG1 . ILE D 1 381 ? -49.574 7.410   -19.827 1.00 43.00  ? 381 ILE D CG1 1 
ATOM   13205 C CG2 . ILE D 1 381 ? -48.909 8.751   -21.824 1.00 38.91  ? 381 ILE D CG2 1 
ATOM   13206 C CD1 . ILE D 1 381 ? -50.606 6.604   -20.590 1.00 42.76  ? 381 ILE D CD1 1 
ATOM   13207 N N   . ALA D 1 382 ? -46.138 9.778   -20.554 1.00 38.43  ? 382 ALA D N   1 
ATOM   13208 C CA  . ALA D 1 382 ? -44.716 9.473   -20.716 1.00 42.76  ? 382 ALA D CA  1 
ATOM   13209 C C   . ALA D 1 382 ? -43.880 10.156  -19.621 1.00 43.39  ? 382 ALA D C   1 
ATOM   13210 O O   . ALA D 1 382 ? -42.897 9.615   -19.167 1.00 41.96  ? 382 ALA D O   1 
ATOM   13211 C CB  . ALA D 1 382 ? -44.245 9.902   -22.116 1.00 46.60  ? 382 ALA D CB  1 
ATOM   13212 N N   . ARG D 1 383 ? -44.250 11.382  -19.266 1.00 49.98  ? 383 ARG D N   1 
ATOM   13213 C CA  . ARG D 1 383 ? -43.398 12.239  -18.450 1.00 51.37  ? 383 ARG D CA  1 
ATOM   13214 C C   . ARG D 1 383 ? -43.482 11.833  -16.977 1.00 46.78  ? 383 ARG D C   1 
ATOM   13215 O O   . ARG D 1 383 ? -42.474 11.741  -16.318 1.00 51.11  ? 383 ARG D O   1 
ATOM   13216 C CB  . ARG D 1 383 ? -43.787 13.718  -18.596 1.00 55.50  ? 383 ARG D CB  1 
ATOM   13217 C CG  . ARG D 1 383 ? -43.261 14.417  -19.849 1.00 63.74  ? 383 ARG D CG  1 
ATOM   13218 C CD  . ARG D 1 383 ? -43.972 15.764  -20.109 1.00 64.57  ? 383 ARG D CD  1 
ATOM   13219 N NE  . ARG D 1 383 ? -44.240 16.493  -18.858 1.00 67.73  ? 383 ARG D NE  1 
ATOM   13220 C CZ  . ARG D 1 383 ? -45.462 16.704  -18.310 1.00 73.20  ? 383 ARG D CZ  1 
ATOM   13221 N NH1 . ARG D 1 383 ? -46.570 16.487  -19.008 1.00 71.43  ? 383 ARG D NH1 1 
ATOM   13222 N NH2 . ARG D 1 383 ? -45.559 17.181  -17.081 1.00 83.03  ? 383 ARG D NH2 1 
ATOM   13223 N N   . ASP D 1 384 ? -44.698 11.675  -16.459 1.00 49.33  ? 384 ASP D N   1 
ATOM   13224 C CA  . ASP D 1 384 ? -44.904 11.578  -15.015 1.00 56.51  ? 384 ASP D CA  1 
ATOM   13225 C C   . ASP D 1 384 ? -45.074 10.117  -14.591 1.00 56.26  ? 384 ASP D C   1 
ATOM   13226 O O   . ASP D 1 384 ? -45.555 9.272   -15.365 1.00 60.05  ? 384 ASP D O   1 
ATOM   13227 C CB  . ASP D 1 384 ? -46.088 12.422  -14.558 1.00 64.80  ? 384 ASP D CB  1 
ATOM   13228 C CG  . ASP D 1 384 ? -45.883 13.923  -14.640 1.00 67.39  ? 384 ASP D CG  1 
ATOM   13229 O OD1 . ASP D 1 384 ? -44.762 14.339  -15.002 1.00 71.72  ? 384 ASP D OD1 1 
ATOM   13230 O OD2 . ASP D 1 384 ? -46.852 14.659  -14.370 1.00 79.07  ? 384 ASP D OD2 1 
ATOM   13231 N N   . GLU D 1 385 ? -44.771 9.861   -13.314 1.00 57.13  ? 385 GLU D N   1 
ATOM   13232 C CA  . GLU D 1 385 ? -44.805 8.520   -12.759 1.00 62.36  ? 385 GLU D CA  1 
ATOM   13233 C C   . GLU D 1 385 ? -46.254 8.077   -12.579 1.00 54.58  ? 385 GLU D C   1 
ATOM   13234 O O   . GLU D 1 385 ? -47.115 8.888   -12.267 1.00 45.15  ? 385 GLU D O   1 
ATOM   13235 C CB  . GLU D 1 385 ? -44.032 8.464   -11.440 1.00 72.93  ? 385 GLU D CB  1 
ATOM   13236 C CG  . GLU D 1 385 ? -44.604 9.367   -10.346 1.00 76.82  ? 385 GLU D CG  1 
ATOM   13237 C CD  . GLU D 1 385 ? -43.527 10.087  -9.535  1.00 88.53  ? 385 GLU D CD  1 
ATOM   13238 O OE1 . GLU D 1 385 ? -42.843 10.977  -10.110 1.00 92.93  ? 385 GLU D OE1 1 
ATOM   13239 O OE2 . GLU D 1 385 ? -43.345 9.746   -8.355  1.00 88.79  ? 385 GLU D OE2 1 
ATOM   13240 N N   . ILE D 1 386 ? -46.499 6.777   -12.807 1.00 46.72  ? 386 ILE D N   1 
ATOM   13241 C CA  . ILE D 1 386 ? -47.802 6.186   -12.613 1.00 46.48  ? 386 ILE D CA  1 
ATOM   13242 C C   . ILE D 1 386 ? -47.704 5.131   -11.505 1.00 46.16  ? 386 ILE D C   1 
ATOM   13243 O O   . ILE D 1 386 ? -46.857 4.255   -11.550 1.00 43.40  ? 386 ILE D O   1 
ATOM   13244 C CB  . ILE D 1 386 ? -48.333 5.567   -13.920 1.00 44.10  ? 386 ILE D CB  1 
ATOM   13245 C CG1 . ILE D 1 386 ? -48.534 6.609   -15.016 1.00 46.91  ? 386 ILE D CG1 1 
ATOM   13246 C CG2 . ILE D 1 386 ? -49.612 4.773   -13.660 1.00 44.43  ? 386 ILE D CG2 1 
ATOM   13247 C CD1 . ILE D 1 386 ? -47.494 6.554   -16.114 1.00 46.99  ? 386 ILE D CD1 1 
ATOM   13248 N N   . PHE D 1 387 ? -48.628 5.181   -10.561 1.00 46.45  ? 387 PHE D N   1 
ATOM   13249 C CA  . PHE D 1 387 ? -48.719 4.157   -9.535  1.00 48.26  ? 387 PHE D CA  1 
ATOM   13250 C C   . PHE D 1 387 ? -50.017 3.397   -9.714  1.00 42.37  ? 387 PHE D C   1 
ATOM   13251 O O   . PHE D 1 387 ? -50.912 3.511   -8.892  1.00 51.64  ? 387 PHE D O   1 
ATOM   13252 C CB  . PHE D 1 387 ? -48.655 4.769   -8.135  1.00 54.36  ? 387 PHE D CB  1 
ATOM   13253 C CG  . PHE D 1 387 ? -47.329 5.407   -7.785  1.00 59.26  ? 387 PHE D CG  1 
ATOM   13254 C CD1 . PHE D 1 387 ? -46.162 4.667   -7.807  1.00 68.73  ? 387 PHE D CD1 1 
ATOM   13255 C CD2 . PHE D 1 387 ? -47.245 6.767   -7.491  1.00 66.84  ? 387 PHE D CD2 1 
ATOM   13256 C CE1 . PHE D 1 387 ? -44.943 5.260   -7.512  1.00 75.35  ? 387 PHE D CE1 1 
ATOM   13257 C CE2 . PHE D 1 387 ? -46.028 7.353   -7.197  1.00 68.58  ? 387 PHE D CE2 1 
ATOM   13258 C CZ  . PHE D 1 387 ? -44.880 6.604   -7.214  1.00 73.16  ? 387 PHE D CZ  1 
ATOM   13259 N N   . GLY D 1 388 ? -50.097 2.618   -10.791 1.00 37.10  ? 388 GLY D N   1 
ATOM   13260 C CA  . GLY D 1 388 ? -51.281 1.837   -11.079 1.00 36.47  ? 388 GLY D CA  1 
ATOM   13261 C C   . GLY D 1 388 ? -51.226 1.209   -12.461 1.00 35.00  ? 388 GLY D C   1 
ATOM   13262 O O   . GLY D 1 388 ? -50.261 1.388   -13.188 1.00 34.71  ? 388 GLY D O   1 
ATOM   13263 N N   . PRO D 1 389 ? -52.287 0.477   -12.865 1.00 33.98  ? 389 PRO D N   1 
ATOM   13264 C CA  . PRO D 1 389 ? -52.289 -0.267  -14.121 1.00 33.55  ? 389 PRO D CA  1 
ATOM   13265 C C   . PRO D 1 389 ? -52.618 0.561   -15.362 1.00 33.51  ? 389 PRO D C   1 
ATOM   13266 O O   . PRO D 1 389 ? -53.494 0.199   -16.146 1.00 31.04  ? 389 PRO D O   1 
ATOM   13267 C CB  . PRO D 1 389 ? -53.368 -1.322  -13.817 1.00 35.06  ? 389 PRO D CB  1 
ATOM   13268 C CG  . PRO D 1 389 ? -54.365 -0.591  -12.936 1.00 32.64  ? 389 PRO D CG  1 
ATOM   13269 C CD  . PRO D 1 389 ? -53.529 0.318   -12.103 1.00 33.07  ? 389 PRO D CD  1 
ATOM   13270 N N   . LEU D 1 390 ? -51.858 1.638   -15.555 1.00 39.20  ? 390 LEU D N   1 
ATOM   13271 C CA  . LEU D 1 390 ? -51.923 2.459   -16.763 1.00 38.36  ? 390 LEU D CA  1 
ATOM   13272 C C   . LEU D 1 390 ? -50.519 2.518   -17.378 1.00 37.43  ? 390 LEU D C   1 
ATOM   13273 O O   . LEU D 1 390 ? -49.558 2.779   -16.667 1.00 40.70  ? 390 LEU D O   1 
ATOM   13274 C CB  . LEU D 1 390 ? -52.438 3.840   -16.352 1.00 37.81  ? 390 LEU D CB  1 
ATOM   13275 C CG  . LEU D 1 390 ? -52.282 4.989   -17.362 1.00 39.83  ? 390 LEU D CG  1 
ATOM   13276 C CD1 . LEU D 1 390 ? -53.230 4.861   -18.530 1.00 41.18  ? 390 LEU D CD1 1 
ATOM   13277 C CD2 . LEU D 1 390 ? -52.510 6.315   -16.662 1.00 39.26  ? 390 LEU D CD2 1 
ATOM   13278 N N   . VAL D 1 391 ? -50.408 2.243   -18.702 1.00 32.26  ? 391 VAL D N   1 
ATOM   13279 C CA  . VAL D 1 391 ? -49.116 2.263   -19.358 1.00 29.84  ? 391 VAL D CA  1 
ATOM   13280 C C   . VAL D 1 391 ? -49.255 2.731   -20.811 1.00 31.07  ? 391 VAL D C   1 
ATOM   13281 O O   . VAL D 1 391 ? -50.283 2.517   -21.463 1.00 32.10  ? 391 VAL D O   1 
ATOM   13282 C CB  . VAL D 1 391 ? -48.456 0.884   -19.262 1.00 30.21  ? 391 VAL D CB  1 
ATOM   13283 C CG1 . VAL D 1 391 ? -49.175 -0.143  -20.111 1.00 33.05  ? 391 VAL D CG1 1 
ATOM   13284 C CG2 . VAL D 1 391 ? -46.989 0.957   -19.614 1.00 29.85  ? 391 VAL D CG2 1 
ATOM   13285 N N   . GLY D 1 392 ? -48.197 3.400   -21.303 1.00 31.68  ? 392 GLY D N   1 
ATOM   13286 C CA  . GLY D 1 392 ? -48.170 3.922   -22.658 1.00 30.79  ? 392 GLY D CA  1 
ATOM   13287 C C   . GLY D 1 392 ? -47.131 3.203   -23.519 1.00 31.85  ? 392 GLY D C   1 
ATOM   13288 O O   . GLY D 1 392 ? -46.067 2.853   -23.044 1.00 32.73  ? 392 GLY D O   1 
ATOM   13289 N N   . LEU D 1 393 ? -47.478 2.981   -24.787 1.00 33.99  ? 393 LEU D N   1 
ATOM   13290 C CA  . LEU D 1 393 ? -46.575 2.388   -25.775 1.00 33.03  ? 393 LEU D CA  1 
ATOM   13291 C C   . LEU D 1 393 ? -46.073 3.484   -26.744 1.00 34.11  ? 393 LEU D C   1 
ATOM   13292 O O   . LEU D 1 393 ? -46.882 4.215   -27.328 1.00 30.93  ? 393 LEU D O   1 
ATOM   13293 C CB  . LEU D 1 393 ? -47.356 1.295   -26.515 1.00 33.83  ? 393 LEU D CB  1 
ATOM   13294 C CG  . LEU D 1 393 ? -47.276 -0.123  -25.941 1.00 34.82  ? 393 LEU D CG  1 
ATOM   13295 C CD1 . LEU D 1 393 ? -47.436 -0.161  -24.459 1.00 34.67  ? 393 LEU D CD1 1 
ATOM   13296 C CD2 . LEU D 1 393 ? -48.303 -1.044  -26.624 1.00 33.11  ? 393 LEU D CD2 1 
ATOM   13297 N N   . LEU D 1 394 ? -44.720 3.586   -26.895 1.00 35.01  ? 394 LEU D N   1 
ATOM   13298 C CA  . LEU D 1 394 ? -44.059 4.614   -27.742 1.00 31.40  ? 394 LEU D CA  1 
ATOM   13299 C C   . LEU D 1 394 ? -43.491 3.897   -28.985 1.00 32.70  ? 394 LEU D C   1 
ATOM   13300 O O   . LEU D 1 394 ? -42.858 2.861   -28.851 1.00 34.45  ? 394 LEU D O   1 
ATOM   13301 C CB  . LEU D 1 394 ? -42.887 5.341   -27.054 1.00 30.43  ? 394 LEU D CB  1 
ATOM   13302 C CG  . LEU D 1 394 ? -43.083 6.202   -25.772 1.00 34.80  ? 394 LEU D CG  1 
ATOM   13303 C CD1 . LEU D 1 394 ? -43.350 7.620   -26.083 1.00 35.66  ? 394 LEU D CD1 1 
ATOM   13304 C CD2 . LEU D 1 394 ? -44.090 5.700   -24.769 1.00 37.65  ? 394 LEU D CD2 1 
ATOM   13305 N N   . ARG D 1 395 ? -43.580 4.530   -30.160 1.00 35.76  ? 395 ARG D N   1 
ATOM   13306 C CA  . ARG D 1 395 ? -42.890 4.040   -31.355 1.00 35.35  ? 395 ARG D CA  1 
ATOM   13307 C C   . ARG D 1 395 ? -41.532 4.704   -31.448 1.00 35.20  ? 395 ARG D C   1 
ATOM   13308 O O   . ARG D 1 395 ? -41.441 5.924   -31.361 1.00 37.95  ? 395 ARG D O   1 
ATOM   13309 C CB  . ARG D 1 395 ? -43.607 4.365   -32.668 1.00 39.03  ? 395 ARG D CB  1 
ATOM   13310 C CG  . ARG D 1 395 ? -45.059 3.940   -32.767 1.00 46.17  ? 395 ARG D CG  1 
ATOM   13311 C CD  . ARG D 1 395 ? -45.590 4.110   -34.212 1.00 44.75  ? 395 ARG D CD  1 
ATOM   13312 N NE  . ARG D 1 395 ? -46.861 3.389   -34.397 1.00 47.10  ? 395 ARG D NE  1 
ATOM   13313 C CZ  . ARG D 1 395 ? -47.045 2.343   -35.190 1.00 51.87  ? 395 ARG D CZ  1 
ATOM   13314 N NH1 . ARG D 1 395 ? -46.013 1.753   -35.776 1.00 55.19  ? 395 ARG D NH1 1 
ATOM   13315 N NH2 . ARG D 1 395 ? -48.263 1.869   -35.373 1.00 59.24  ? 395 ARG D NH2 1 
ATOM   13316 N N   . ALA D 1 396 ? -40.485 3.891   -31.705 1.00 37.68  ? 396 ALA D N   1 
ATOM   13317 C CA  . ALA D 1 396 ? -39.133 4.406   -31.922 1.00 41.07  ? 396 ALA D CA  1 
ATOM   13318 C C   . ALA D 1 396 ? -38.690 4.135   -33.373 1.00 40.20  ? 396 ALA D C   1 
ATOM   13319 O O   . ALA D 1 396 ? -38.797 2.998   -33.867 1.00 42.18  ? 396 ALA D O   1 
ATOM   13320 C CB  . ALA D 1 396 ? -38.178 3.787   -30.913 1.00 39.60  ? 396 ALA D CB  1 
ATOM   13321 N N   . ARG D 1 397 ? -38.149 5.180   -34.022 1.00 42.49  ? 397 ARG D N   1 
ATOM   13322 C CA  . ARG D 1 397 ? -37.752 5.115   -35.433 1.00 44.21  ? 397 ARG D CA  1 
ATOM   13323 C C   . ARG D 1 397 ? -36.549 4.195   -35.598 1.00 43.85  ? 397 ARG D C   1 
ATOM   13324 O O   . ARG D 1 397 ? -36.529 3.381   -36.514 1.00 47.95  ? 397 ARG D O   1 
ATOM   13325 C CB  . ARG D 1 397 ? -37.396 6.498   -35.988 1.00 41.97  ? 397 ARG D CB  1 
ATOM   13326 C CG  . ARG D 1 397 ? -38.525 7.505   -35.869 1.00 48.14  ? 397 ARG D CG  1 
ATOM   13327 C CD  . ARG D 1 397 ? -38.209 8.895   -36.533 1.00 50.53  ? 397 ARG D CD  1 
ATOM   13328 N NE  . ARG D 1 397 ? -37.011 9.536   -35.969 1.00 49.31  ? 397 ARG D NE  1 
ATOM   13329 C CZ  . ARG D 1 397 ? -37.011 10.460  -35.009 1.00 50.62  ? 397 ARG D CZ  1 
ATOM   13330 N NH1 . ARG D 1 397 ? -38.143 10.901  -34.512 1.00 52.27  ? 397 ARG D NH1 1 
ATOM   13331 N NH2 . ARG D 1 397 ? -35.873 10.956  -34.570 1.00 53.91  ? 397 ARG D NH2 1 
ATOM   13332 N N   . ASP D 1 398 ? -35.535 4.382   -34.717 1.00 46.04  ? 398 ASP D N   1 
ATOM   13333 C CA  . ASP D 1 398 ? -34.297 3.610   -34.735 1.00 42.90  ? 398 ASP D CA  1 
ATOM   13334 C C   . ASP D 1 398 ? -33.720 3.578   -33.312 1.00 42.33  ? 398 ASP D C   1 
ATOM   13335 O O   . ASP D 1 398 ? -34.337 4.090   -32.389 1.00 44.60  ? 398 ASP D O   1 
ATOM   13336 C CB  . ASP D 1 398 ? -33.320 4.216   -35.720 1.00 41.86  ? 398 ASP D CB  1 
ATOM   13337 C CG  . ASP D 1 398 ? -33.176 5.727   -35.617 1.00 42.99  ? 398 ASP D CG  1 
ATOM   13338 O OD1 . ASP D 1 398 ? -33.169 6.241   -34.483 1.00 41.30  ? 398 ASP D OD1 1 
ATOM   13339 O OD2 . ASP D 1 398 ? -33.081 6.369   -36.654 1.00 49.33  ? 398 ASP D OD2 1 
ATOM   13340 N N   . GLU D 1 399 ? -32.536 2.960   -33.156 1.00 44.06  ? 399 GLU D N   1 
ATOM   13341 C CA  . GLU D 1 399 ? -31.878 2.821   -31.860 1.00 45.40  ? 399 GLU D CA  1 
ATOM   13342 C C   . GLU D 1 399 ? -31.588 4.206   -31.239 1.00 44.81  ? 399 GLU D C   1 
ATOM   13343 O O   . GLU D 1 399 ? -31.806 4.409   -30.047 1.00 46.92  ? 399 GLU D O   1 
ATOM   13344 C CB  . GLU D 1 399 ? -30.604 1.987   -32.007 1.00 46.13  ? 399 GLU D CB  1 
ATOM   13345 C CG  . GLU D 1 399 ? -29.887 1.715   -30.679 1.00 55.08  ? 399 GLU D CG  1 
ATOM   13346 C CD  . GLU D 1 399 ? -28.693 0.740   -30.737 1.00 56.87  ? 399 GLU D CD  1 
ATOM   13347 O OE1 . GLU D 1 399 ? -28.578 -0.037  -31.709 1.00 55.44  ? 399 GLU D OE1 1 
ATOM   13348 O OE2 . GLU D 1 399 ? -27.876 0.772   -29.788 1.00 59.42  ? 399 GLU D OE2 1 
ATOM   13349 N N   . ALA D 1 400 ? -31.093 5.150   -32.045 1.00 40.57  ? 400 ALA D N   1 
ATOM   13350 C CA  . ALA D 1 400 ? -30.797 6.490   -31.540 1.00 39.89  ? 400 ALA D CA  1 
ATOM   13351 C C   . ALA D 1 400 ? -32.072 7.159   -31.009 1.00 39.83  ? 400 ALA D C   1 
ATOM   13352 O O   . ALA D 1 400 ? -32.043 7.797   -29.982 1.00 41.15  ? 400 ALA D O   1 
ATOM   13353 C CB  . ALA D 1 400 ? -30.156 7.322   -32.614 1.00 39.30  ? 400 ALA D CB  1 
ATOM   13354 N N   . HIS D 1 401 ? -33.180 7.017   -31.734 1.00 41.26  ? 401 HIS D N   1 
ATOM   13355 C CA  . HIS D 1 401 ? -34.461 7.590   -31.306 1.00 43.40  ? 401 HIS D CA  1 
ATOM   13356 C C   . HIS D 1 401 ? -34.950 6.905   -30.021 1.00 40.72  ? 401 HIS D C   1 
ATOM   13357 O O   . HIS D 1 401 ? -35.467 7.564   -29.120 1.00 41.67  ? 401 HIS D O   1 
ATOM   13358 C CB  . HIS D 1 401 ? -35.501 7.504   -32.433 1.00 44.32  ? 401 HIS D CB  1 
ATOM   13359 C CG  . HIS D 1 401 ? -36.755 8.262   -32.154 1.00 43.65  ? 401 HIS D CG  1 
ATOM   13360 N ND1 . HIS D 1 401 ? -38.012 7.751   -32.442 1.00 42.96  ? 401 HIS D ND1 1 
ATOM   13361 C CD2 . HIS D 1 401 ? -36.963 9.453   -31.557 1.00 41.37  ? 401 HIS D CD2 1 
ATOM   13362 C CE1 . HIS D 1 401 ? -38.945 8.615   -32.037 1.00 40.60  ? 401 HIS D CE1 1 
ATOM   13363 N NE2 . HIS D 1 401 ? -38.339 9.660   -31.505 1.00 38.38  ? 401 HIS D NE2 1 
ATOM   13364 N N   . ALA D 1 402 ? -34.747 5.583   -29.929 1.00 39.45  ? 402 ALA D N   1 
ATOM   13365 C CA  . ALA D 1 402 ? -35.106 4.832   -28.726 1.00 37.08  ? 402 ALA D CA  1 
ATOM   13366 C C   . ALA D 1 402 ? -34.341 5.362   -27.516 1.00 37.11  ? 402 ALA D C   1 
ATOM   13367 O O   . ALA D 1 402 ? -34.903 5.501   -26.445 1.00 36.00  ? 402 ALA D O   1 
ATOM   13368 C CB  . ALA D 1 402 ? -34.860 3.368   -28.934 1.00 37.94  ? 402 ALA D CB  1 
ATOM   13369 N N   . LEU D 1 403 ? -33.055 5.676   -27.707 1.00 40.64  ? 403 LEU D N   1 
ATOM   13370 C CA  . LEU D 1 403 ? -32.238 6.182   -26.628 1.00 42.64  ? 403 LEU D CA  1 
ATOM   13371 C C   . LEU D 1 403 ? -32.758 7.563   -26.184 1.00 47.38  ? 403 LEU D C   1 
ATOM   13372 O O   . LEU D 1 403 ? -32.839 7.860   -24.991 1.00 47.53  ? 403 LEU D O   1 
ATOM   13373 C CB  . LEU D 1 403 ? -30.775 6.259   -27.049 1.00 46.89  ? 403 LEU D CB  1 
ATOM   13374 C CG  . LEU D 1 403 ? -29.824 6.791   -25.971 1.00 50.65  ? 403 LEU D CG  1 
ATOM   13375 C CD1 . LEU D 1 403 ? -29.735 5.762   -24.864 1.00 50.53  ? 403 LEU D CD1 1 
ATOM   13376 C CD2 . LEU D 1 403 ? -28.436 7.146   -26.500 1.00 53.90  ? 403 LEU D CD2 1 
ATOM   13377 N N   . GLU D 1 404 ? -33.059 8.417   -27.145 1.00 47.85  ? 404 GLU D N   1 
ATOM   13378 C CA  . GLU D 1 404 ? -33.507 9.765   -26.832 1.00 48.89  ? 404 GLU D CA  1 
ATOM   13379 C C   . GLU D 1 404 ? -34.810 9.700   -26.033 1.00 43.51  ? 404 GLU D C   1 
ATOM   13380 O O   . GLU D 1 404 ? -34.980 10.441  -25.076 1.00 41.50  ? 404 GLU D O   1 
ATOM   13381 C CB  . GLU D 1 404 ? -33.665 10.567  -28.121 1.00 50.02  ? 404 GLU D CB  1 
ATOM   13382 C CG  . GLU D 1 404 ? -34.390 11.891  -27.928 1.00 57.29  ? 404 GLU D CG  1 
ATOM   13383 C CD  . GLU D 1 404 ? -34.673 12.628  -29.235 1.00 62.41  ? 404 GLU D CD  1 
ATOM   13384 O OE1 . GLU D 1 404 ? -34.286 12.129  -30.322 1.00 59.20  ? 404 GLU D OE1 1 
ATOM   13385 O OE2 . GLU D 1 404 ? -35.292 13.699  -29.157 1.00 69.87  ? 404 GLU D OE2 1 
ATOM   13386 N N   . LEU D 1 405 ? -35.733 8.822   -26.465 1.00 38.53  ? 405 LEU D N   1 
ATOM   13387 C CA  . LEU D 1 405 ? -37.021 8.671   -25.794 1.00 40.80  ? 405 LEU D CA  1 
ATOM   13388 C C   . LEU D 1 405 ? -36.781 8.184   -24.362 1.00 38.39  ? 405 LEU D C   1 
ATOM   13389 O O   . LEU D 1 405 ? -37.380 8.704   -23.430 1.00 38.95  ? 405 LEU D O   1 
ATOM   13390 C CB  . LEU D 1 405 ? -37.987 7.731   -26.536 1.00 37.67  ? 405 LEU D CB  1 
ATOM   13391 C CG  . LEU D 1 405 ? -38.496 8.195   -27.914 1.00 38.42  ? 405 LEU D CG  1 
ATOM   13392 C CD1 . LEU D 1 405 ? -39.223 7.071   -28.640 1.00 37.54  ? 405 LEU D CD1 1 
ATOM   13393 C CD2 . LEU D 1 405 ? -39.389 9.378   -27.798 1.00 38.44  ? 405 LEU D CD2 1 
ATOM   13394 N N   . ALA D 1 406 ? -35.892 7.196   -24.194 1.00 36.16  ? 406 ALA D N   1 
ATOM   13395 C CA  . ALA D 1 406 ? -35.668 6.605   -22.865 1.00 40.03  ? 406 ALA D CA  1 
ATOM   13396 C C   . ALA D 1 406 ? -35.072 7.641   -21.906 1.00 43.48  ? 406 ALA D C   1 
ATOM   13397 O O   . ALA D 1 406 ? -35.446 7.682   -20.745 1.00 47.84  ? 406 ALA D O   1 
ATOM   13398 C CB  . ALA D 1 406 ? -34.791 5.384   -22.958 1.00 36.77  ? 406 ALA D CB  1 
ATOM   13399 N N   . ASN D 1 407 ? -34.175 8.505   -22.416 1.00 44.28  ? 407 ASN D N   1 
ATOM   13400 C CA  . ASN D 1 407 ? -33.502 9.487   -21.573 1.00 41.93  ? 407 ASN D CA  1 
ATOM   13401 C C   . ASN D 1 407 ? -34.321 10.757  -21.431 1.00 44.67  ? 407 ASN D C   1 
ATOM   13402 O O   . ASN D 1 407 ? -33.917 11.657  -20.687 1.00 46.72  ? 407 ASN D O   1 
ATOM   13403 C CB  . ASN D 1 407 ? -32.124 9.854   -22.096 1.00 42.71  ? 407 ASN D CB  1 
ATOM   13404 C CG  . ASN D 1 407 ? -31.083 8.811   -21.762 1.00 47.35  ? 407 ASN D CG  1 
ATOM   13405 O OD1 . ASN D 1 407 ? -31.312 7.941   -20.908 1.00 47.58  ? 407 ASN D OD1 1 
ATOM   13406 N ND2 . ASN D 1 407 ? -29.936 8.881   -22.422 1.00 48.93  ? 407 ASN D ND2 1 
ATOM   13407 N N   . ALA D 1 408 ? -35.460 10.858  -22.144 1.00 50.96  ? 408 ALA D N   1 
ATOM   13408 C CA  . ALA D 1 408 ? -36.287 12.070  -22.039 1.00 55.18  ? 408 ALA D CA  1 
ATOM   13409 C C   . ALA D 1 408 ? -36.942 12.132  -20.657 1.00 60.91  ? 408 ALA D C   1 
ATOM   13410 O O   . ALA D 1 408 ? -37.231 13.212  -20.160 1.00 57.46  ? 408 ALA D O   1 
ATOM   13411 C CB  . ALA D 1 408 ? -37.319 12.121  -23.143 1.00 52.20  ? 408 ALA D CB  1 
ATOM   13412 N N   . SER D 1 409 ? -37.144 10.950  -20.042 1.00 77.50  ? 409 SER D N   1 
ATOM   13413 C CA  . SER D 1 409 ? -37.798 10.830  -18.739 1.00 87.25  ? 409 SER D CA  1 
ATOM   13414 C C   . SER D 1 409 ? -37.030 11.622  -17.697 1.00 92.31  ? 409 SER D C   1 
ATOM   13415 O O   . SER D 1 409 ? -37.605 12.070  -16.716 1.00 87.65  ? 409 SER D O   1 
ATOM   13416 C CB  . SER D 1 409 ? -37.922 9.360   -18.319 1.00 91.60  ? 409 SER D CB  1 
ATOM   13417 O OG  . SER D 1 409 ? -36.638 8.743   -18.177 1.00 82.54  ? 409 SER D OG  1 
ATOM   13418 N N   . GLU D 1 410 ? -35.713 11.730  -17.921 1.00 112.21 ? 410 GLU D N   1 
ATOM   13419 C CA  . GLU D 1 410 ? -34.764 12.437  -17.051 1.00 134.23 ? 410 GLU D CA  1 
ATOM   13420 C C   . GLU D 1 410 ? -34.604 11.693  -15.708 1.00 138.15 ? 410 GLU D C   1 
ATOM   13421 O O   . GLU D 1 410 ? -33.500 11.247  -15.388 1.00 117.15 ? 410 GLU D O   1 
ATOM   13422 C CB  . GLU D 1 410 ? -34.935 13.984  -16.979 1.00 137.15 ? 410 GLU D CB  1 
ATOM   13423 C CG  . GLU D 1 410 ? -36.325 14.512  -16.603 1.00 132.11 ? 410 GLU D CG  1 
ATOM   13424 C CD  . GLU D 1 410 ? -36.683 14.421  -15.134 1.00 125.28 ? 410 GLU D CD  1 
ATOM   13425 O OE1 . GLU D 1 410 ? -37.860 14.645  -14.820 1.00 111.56 ? 410 GLU D OE1 1 
ATOM   13426 O OE2 . GLU D 1 410 ? -35.797 14.114  -14.311 1.00 131.70 ? 410 GLU D OE2 1 
ATOM   13427 N N   . TYR D 1 411 ? -35.690 11.541  -14.941 1.00 151.65 ? 411 TYR D N   1 
ATOM   13428 C CA  . TYR D 1 411 ? -35.599 10.873  -13.646 1.00 160.89 ? 411 TYR D CA  1 
ATOM   13429 C C   . TYR D 1 411 ? -35.847 9.372   -13.854 1.00 153.20 ? 411 TYR D C   1 
ATOM   13430 O O   . TYR D 1 411 ? -36.946 8.960   -14.227 1.00 131.93 ? 411 TYR D O   1 
ATOM   13431 C CB  . TYR D 1 411 ? -36.506 11.529  -12.584 1.00 167.18 ? 411 TYR D CB  1 
ATOM   13432 N N   . GLY D 1 412 ? -34.787 8.568   -13.629 1.00 145.50 ? 412 GLY D N   1 
ATOM   13433 C CA  . GLY D 1 412 ? -34.784 7.148   -13.974 1.00 133.89 ? 412 GLY D CA  1 
ATOM   13434 C C   . GLY D 1 412 ? -34.265 6.281   -12.816 1.00 121.82 ? 412 GLY D C   1 
ATOM   13435 O O   . GLY D 1 412 ? -33.050 6.152   -12.611 1.00 109.15 ? 412 GLY D O   1 
ATOM   13436 N N   . LEU D 1 413 ? -35.200 5.648   -12.094 1.00 106.26 ? 413 LEU D N   1 
ATOM   13437 C CA  . LEU D 1 413 ? -34.852 4.743   -11.010 1.00 100.23 ? 413 LEU D CA  1 
ATOM   13438 C C   . LEU D 1 413 ? -34.401 3.401   -11.595 1.00 83.60  ? 413 LEU D C   1 
ATOM   13439 O O   . LEU D 1 413 ? -33.340 2.901   -11.242 1.00 72.22  ? 413 LEU D O   1 
ATOM   13440 C CB  . LEU D 1 413 ? -36.044 4.579   -10.061 1.00 109.79 ? 413 LEU D CB  1 
ATOM   13441 C CG  . LEU D 1 413 ? -35.709 4.230   -8.601  1.00 109.13 ? 413 LEU D CG  1 
ATOM   13442 C CD1 . LEU D 1 413 ? -34.559 5.087   -8.052  1.00 101.61 ? 413 LEU D CD1 1 
ATOM   13443 C CD2 . LEU D 1 413 ? -36.954 4.384   -7.721  1.00 107.71 ? 413 LEU D CD2 1 
ATOM   13444 N N   . SER D 1 414 ? -35.220 2.840   -12.502 1.00 64.34  ? 414 SER D N   1 
ATOM   13445 C CA  . SER D 1 414 ? -34.921 1.571   -13.137 1.00 53.81  ? 414 SER D CA  1 
ATOM   13446 C C   . SER D 1 414 ? -35.109 1.687   -14.652 1.00 48.38  ? 414 SER D C   1 
ATOM   13447 O O   . SER D 1 414 ? -35.576 2.712   -15.152 1.00 47.79  ? 414 SER D O   1 
ATOM   13448 C CB  . SER D 1 414 ? -35.759 0.479   -12.566 1.00 52.80  ? 414 SER D CB  1 
ATOM   13449 O OG  . SER D 1 414 ? -35.285 -0.784  -12.994 1.00 66.77  ? 414 SER D OG  1 
ATOM   13450 N N   . SER D 1 415 ? -34.710 0.628   -15.372 1.00 43.55  ? 415 SER D N   1 
ATOM   13451 C CA  . SER D 1 415 ? -34.884 0.551   -16.811 1.00 36.97  ? 415 SER D CA  1 
ATOM   13452 C C   . SER D 1 415 ? -34.707 -0.890  -17.268 1.00 37.78  ? 415 SER D C   1 
ATOM   13453 O O   . SER D 1 415 ? -34.223 -1.726  -16.518 1.00 41.23  ? 415 SER D O   1 
ATOM   13454 C CB  . SER D 1 415 ? -33.929 1.470   -17.527 1.00 41.45  ? 415 SER D CB  1 
ATOM   13455 O OG  . SER D 1 415 ? -32.593 1.291   -17.067 1.00 45.26  ? 415 SER D OG  1 
ATOM   13456 N N   . ALA D 1 416 ? -35.083 -1.160  -18.524 1.00 37.05  ? 416 ALA D N   1 
ATOM   13457 C CA  . ALA D 1 416 ? -34.894 -2.466  -19.130 1.00 33.97  ? 416 ALA D CA  1 
ATOM   13458 C C   . ALA D 1 416 ? -34.676 -2.295  -20.627 1.00 35.88  ? 416 ALA D C   1 
ATOM   13459 O O   . ALA D 1 416 ? -35.219 -1.352  -21.257 1.00 34.31  ? 416 ALA D O   1 
ATOM   13460 C CB  . ALA D 1 416 ? -36.098 -3.362  -18.847 1.00 33.44  ? 416 ALA D CB  1 
ATOM   13461 N N   . VAL D 1 417 ? -33.898 -3.216  -21.199 1.00 37.34  ? 417 VAL D N   1 
ATOM   13462 C CA  . VAL D 1 417 ? -33.586 -3.188  -22.621 1.00 43.10  ? 417 VAL D CA  1 
ATOM   13463 C C   . VAL D 1 417 ? -33.529 -4.628  -23.110 1.00 40.02  ? 417 VAL D C   1 
ATOM   13464 O O   . VAL D 1 417 ? -32.939 -5.487  -22.457 1.00 37.18  ? 417 VAL D O   1 
ATOM   13465 C CB  . VAL D 1 417 ? -32.280 -2.404  -22.978 1.00 47.43  ? 417 VAL D CB  1 
ATOM   13466 C CG1 . VAL D 1 417 ? -31.128 -2.780  -22.094 1.00 53.89  ? 417 VAL D CG1 1 
ATOM   13467 C CG2 . VAL D 1 417 ? -31.885 -2.577  -24.440 1.00 49.10  ? 417 VAL D CG2 1 
ATOM   13468 N N   . PHE D 1 418 ? -34.182 -4.877  -24.254 1.00 40.04  ? 418 PHE D N   1 
ATOM   13469 C CA  . PHE D 1 418 ? -34.318 -6.213  -24.807 1.00 37.30  ? 418 PHE D CA  1 
ATOM   13470 C C   . PHE D 1 418 ? -33.707 -6.244  -26.193 1.00 41.43  ? 418 PHE D C   1 
ATOM   13471 O O   . PHE D 1 418 ? -34.062 -5.452  -27.060 1.00 38.45  ? 418 PHE D O   1 
ATOM   13472 C CB  . PHE D 1 418 ? -35.786 -6.634  -24.841 1.00 38.18  ? 418 PHE D CB  1 
ATOM   13473 C CG  . PHE D 1 418 ? -36.219 -7.366  -23.592 1.00 38.79  ? 418 PHE D CG  1 
ATOM   13474 C CD1 . PHE D 1 418 ? -36.576 -6.667  -22.437 1.00 36.76  ? 418 PHE D CD1 1 
ATOM   13475 C CD2 . PHE D 1 418 ? -36.223 -8.764  -23.557 1.00 39.66  ? 418 PHE D CD2 1 
ATOM   13476 C CE1 . PHE D 1 418 ? -36.909 -7.356  -21.273 1.00 40.66  ? 418 PHE D CE1 1 
ATOM   13477 C CE2 . PHE D 1 418 ? -36.566 -9.444  -22.397 1.00 38.49  ? 418 PHE D CE2 1 
ATOM   13478 C CZ  . PHE D 1 418 ? -36.908 -8.748  -21.260 1.00 36.99  ? 418 PHE D CZ  1 
ATOM   13479 N N   . SER D 1 419 ? -32.778 -7.167  -26.380 1.00 49.14  ? 419 SER D N   1 
ATOM   13480 C CA  . SER D 1 419 ? -32.106 -7.361  -27.654 1.00 48.48  ? 419 SER D CA  1 
ATOM   13481 C C   . SER D 1 419 ? -31.274 -8.625  -27.579 1.00 52.55  ? 419 SER D C   1 
ATOM   13482 O O   . SER D 1 419 ? -30.543 -8.826  -26.616 1.00 56.92  ? 419 SER D O   1 
ATOM   13483 C CB  . SER D 1 419 ? -31.232 -6.167  -28.025 1.00 45.37  ? 419 SER D CB  1 
ATOM   13484 O OG  . SER D 1 419 ? -30.224 -6.534  -28.966 1.00 44.77  ? 419 SER D OG  1 
ATOM   13485 N N   . ARG D 1 420 ? -31.322 -9.416  -28.642 1.00 55.02  ? 420 ARG D N   1 
ATOM   13486 C CA  . ARG D 1 420 ? -30.590 -10.664 -28.699 1.00 66.08  ? 420 ARG D CA  1 
ATOM   13487 C C   . ARG D 1 420 ? -29.081 -10.418 -28.776 1.00 65.55  ? 420 ARG D C   1 
ATOM   13488 O O   . ARG D 1 420 ? -28.310 -11.300 -28.430 1.00 71.69  ? 420 ARG D O   1 
ATOM   13489 C CB  . ARG D 1 420 ? -31.048 -11.499 -29.896 1.00 50.00  ? 420 ARG D CB  1 
ATOM   13490 C CG  . ARG D 1 420 ? -32.478 -12.004 -29.789 1.00 50.00  ? 420 ARG D CG  1 
ATOM   13491 C CD  . ARG D 1 420 ? -32.918 -12.874 -30.956 1.00 50.00  ? 420 ARG D CD  1 
ATOM   13492 N NE  . ARG D 1 420 ? -34.317 -13.277 -30.842 1.00 50.00  ? 420 ARG D NE  1 
ATOM   13493 C CZ  . ARG D 1 420 ? -34.980 -13.939 -31.779 1.00 50.00  ? 420 ARG D CZ  1 
ATOM   13494 N NH1 . ARG D 1 420 ? -34.373 -14.282 -32.908 1.00 50.00  ? 420 ARG D NH1 1 
ATOM   13495 N NH2 . ARG D 1 420 ? -36.252 -14.264 -31.590 1.00 50.00  ? 420 ARG D NH2 1 
ATOM   13496 N N   . ASP D 1 421 ? -28.666 -9.244  -29.244 1.00 53.45  ? 421 ASP D N   1 
ATOM   13497 C CA  . ASP D 1 421 ? -27.251 -8.906  -29.264 1.00 58.79  ? 421 ASP D CA  1 
ATOM   13498 C C   . ASP D 1 421 ? -26.862 -8.260  -27.923 1.00 56.68  ? 421 ASP D C   1 
ATOM   13499 O O   . ASP D 1 421 ? -27.146 -7.088  -27.697 1.00 54.80  ? 421 ASP D O   1 
ATOM   13500 C CB  . ASP D 1 421 ? -26.908 -8.040  -30.475 1.00 60.88  ? 421 ASP D CB  1 
ATOM   13501 C CG  . ASP D 1 421 ? -25.444 -7.627  -30.589 1.00 64.56  ? 421 ASP D CG  1 
ATOM   13502 O OD1 . ASP D 1 421 ? -24.626 -8.149  -29.805 1.00 67.90  ? 421 ASP D OD1 1 
ATOM   13503 O OD2 . ASP D 1 421 ? -25.140 -6.746  -31.441 1.00 64.09  ? 421 ASP D OD2 1 
ATOM   13504 N N   . LEU D 1 422 ? -26.164 -9.032  -27.060 1.00 56.42  ? 422 LEU D N   1 
ATOM   13505 C CA  . LEU D 1 422 ? -25.859 -8.601  -25.691 1.00 53.37  ? 422 LEU D CA  1 
ATOM   13506 C C   . LEU D 1 422 ? -24.897 -7.422  -25.720 1.00 55.82  ? 422 LEU D C   1 
ATOM   13507 O O   . LEU D 1 422 ? -24.998 -6.509  -24.892 1.00 57.11  ? 422 LEU D O   1 
ATOM   13508 C CB  . LEU D 1 422 ? -25.280 -9.733  -24.848 1.00 57.34  ? 422 LEU D CB  1 
ATOM   13509 C CG  . LEU D 1 422 ? -26.280 -10.735 -24.251 1.00 70.09  ? 422 LEU D CG  1 
ATOM   13510 C CD1 . LEU D 1 422 ? -27.548 -10.062 -23.743 1.00 70.86  ? 422 LEU D CD1 1 
ATOM   13511 C CD2 . LEU D 1 422 ? -26.623 -11.821 -25.253 1.00 81.76  ? 422 LEU D CD2 1 
ATOM   13512 N N   . GLU D 1 423 ? -23.962 -7.455  -26.661 1.00 51.46  ? 423 GLU D N   1 
ATOM   13513 C CA  . GLU D 1 423 ? -22.988 -6.387  -26.805 1.00 56.72  ? 423 GLU D CA  1 
ATOM   13514 C C   . GLU D 1 423 ? -23.714 -5.065  -27.068 1.00 52.98  ? 423 GLU D C   1 
ATOM   13515 O O   . GLU D 1 423 ? -23.403 -4.051  -26.446 1.00 48.84  ? 423 GLU D O   1 
ATOM   13516 C CB  . GLU D 1 423 ? -21.989 -6.696  -27.932 1.00 67.87  ? 423 GLU D CB  1 
ATOM   13517 C CG  . GLU D 1 423 ? -20.947 -5.594  -28.131 1.00 75.13  ? 423 GLU D CG  1 
ATOM   13518 C CD  . GLU D 1 423 ? -19.719 -6.002  -28.922 1.00 91.03  ? 423 GLU D CD  1 
ATOM   13519 O OE1 . GLU D 1 423 ? -19.787 -7.069  -29.591 1.00 102.98 ? 423 GLU D OE1 1 
ATOM   13520 O OE2 . GLU D 1 423 ? -18.680 -5.259  -28.868 1.00 80.61  ? 423 GLU D OE2 1 
ATOM   13521 N N   . ARG D 1 424 ? -24.664 -5.085  -28.019 1.00 52.74  ? 424 ARG D N   1 
ATOM   13522 C CA  . ARG D 1 424 ? -25.418 -3.890  -28.381 1.00 51.14  ? 424 ARG D CA  1 
ATOM   13523 C C   . ARG D 1 424 ? -26.267 -3.438  -27.181 1.00 47.58  ? 424 ARG D C   1 
ATOM   13524 O O   . ARG D 1 424 ? -26.309 -2.234  -26.849 1.00 38.59  ? 424 ARG D O   1 
ATOM   13525 C CB  . ARG D 1 424 ? -26.267 -4.164  -29.624 1.00 51.03  ? 424 ARG D CB  1 
ATOM   13526 C CG  . ARG D 1 424 ? -27.307 -3.110  -29.938 1.00 55.96  ? 424 ARG D CG  1 
ATOM   13527 C CD  . ARG D 1 424 ? -28.393 -3.685  -30.836 1.00 61.08  ? 424 ARG D CD  1 
ATOM   13528 N NE  . ARG D 1 424 ? -29.092 -2.626  -31.584 1.00 66.12  ? 424 ARG D NE  1 
ATOM   13529 C CZ  . ARG D 1 424 ? -30.242 -2.785  -32.219 1.00 62.36  ? 424 ARG D CZ  1 
ATOM   13530 N NH1 . ARG D 1 424 ? -30.781 -3.995  -32.321 1.00 60.83  ? 424 ARG D NH1 1 
ATOM   13531 N NH2 . ARG D 1 424 ? -30.852 -1.733  -32.748 1.00 66.96  ? 424 ARG D NH2 1 
ATOM   13532 N N   . ALA D 1 425 ? -26.908 -4.414  -26.518 1.00 40.91  ? 425 ALA D N   1 
ATOM   13533 C CA  . ALA D 1 425 ? -27.803 -4.128  -25.412 1.00 42.43  ? 425 ALA D CA  1 
ATOM   13534 C C   . ALA D 1 425 ? -27.033 -3.449  -24.273 1.00 45.34  ? 425 ALA D C   1 
ATOM   13535 O O   . ALA D 1 425 ? -27.530 -2.483  -23.659 1.00 43.88  ? 425 ALA D O   1 
ATOM   13536 C CB  . ALA D 1 425 ? -28.481 -5.396  -24.958 1.00 43.32  ? 425 ALA D CB  1 
ATOM   13537 N N   . VAL D 1 426 ? -25.805 -3.924  -24.009 1.00 45.67  ? 426 VAL D N   1 
ATOM   13538 C CA  . VAL D 1 426 ? -25.042 -3.423  -22.874 1.00 42.76  ? 426 VAL D CA  1 
ATOM   13539 C C   . VAL D 1 426 ? -24.518 -2.022  -23.205 1.00 42.86  ? 426 VAL D C   1 
ATOM   13540 O O   . VAL D 1 426 ? -24.597 -1.101  -22.364 1.00 40.07  ? 426 VAL D O   1 
ATOM   13541 C CB  . VAL D 1 426 ? -23.909 -4.376  -22.458 1.00 43.39  ? 426 VAL D CB  1 
ATOM   13542 C CG1 . VAL D 1 426 ? -22.930 -3.704  -21.520 1.00 45.78  ? 426 VAL D CG1 1 
ATOM   13543 C CG2 . VAL D 1 426 ? -24.450 -5.645  -21.817 1.00 42.74  ? 426 VAL D CG2 1 
ATOM   13544 N N   . ARG D 1 427 ? -24.052 -1.850  -24.440 1.00 40.93  ? 427 ARG D N   1 
ATOM   13545 C CA  . ARG D 1 427 ? -23.572 -0.552  -24.911 1.00 48.98  ? 427 ARG D CA  1 
ATOM   13546 C C   . ARG D 1 427 ? -24.707 0.505   -24.867 1.00 43.36  ? 427 ARG D C   1 
ATOM   13547 O O   . ARG D 1 427 ? -24.478 1.634   -24.452 1.00 41.44  ? 427 ARG D O   1 
ATOM   13548 C CB  . ARG D 1 427 ? -22.993 -0.694  -26.318 1.00 54.25  ? 427 ARG D CB  1 
ATOM   13549 C CG  . ARG D 1 427 ? -22.189 0.510   -26.773 1.00 58.80  ? 427 ARG D CG  1 
ATOM   13550 C CD  . ARG D 1 427 ? -22.298 0.713   -28.277 1.00 65.30  ? 427 ARG D CD  1 
ATOM   13551 N NE  . ARG D 1 427 ? -22.135 -0.546  -29.026 1.00 71.84  ? 427 ARG D NE  1 
ATOM   13552 C CZ  . ARG D 1 427 ? -22.932 -0.972  -30.038 1.00 80.57  ? 427 ARG D CZ  1 
ATOM   13553 N NH1 . ARG D 1 427 ? -23.898 -0.191  -30.515 1.00 82.66  ? 427 ARG D NH1 1 
ATOM   13554 N NH2 . ARG D 1 427 ? -22.744 -2.175  -30.568 1.00 78.47  ? 427 ARG D NH2 1 
ATOM   13555 N N   . PHE D 1 428 ? -25.935 0.102   -25.256 1.00 41.42  ? 428 PHE D N   1 
ATOM   13556 C CA  . PHE D 1 428 ? -27.116 0.964   -25.164 1.00 36.07  ? 428 PHE D CA  1 
ATOM   13557 C C   . PHE D 1 428 ? -27.441 1.243   -23.693 1.00 37.53  ? 428 PHE D C   1 
ATOM   13558 O O   . PHE D 1 428 ? -27.653 2.401   -23.305 1.00 32.95  ? 428 PHE D O   1 
ATOM   13559 C CB  . PHE D 1 428 ? -28.289 0.293   -25.876 1.00 39.87  ? 428 PHE D CB  1 
ATOM   13560 C CG  . PHE D 1 428 ? -29.584 1.096   -25.862 1.00 44.59  ? 428 PHE D CG  1 
ATOM   13561 C CD1 . PHE D 1 428 ? -30.437 1.064   -24.757 1.00 43.57  ? 428 PHE D CD1 1 
ATOM   13562 C CD2 . PHE D 1 428 ? -29.953 1.880   -26.957 1.00 43.34  ? 428 PHE D CD2 1 
ATOM   13563 C CE1 . PHE D 1 428 ? -31.609 1.805   -24.744 1.00 44.55  ? 428 PHE D CE1 1 
ATOM   13564 C CE2 . PHE D 1 428 ? -31.133 2.620   -26.935 1.00 41.44  ? 428 PHE D CE2 1 
ATOM   13565 C CZ  . PHE D 1 428 ? -31.962 2.568   -25.842 1.00 43.39  ? 428 PHE D CZ  1 
ATOM   13566 N N   . ALA D 1 429 ? -27.428 0.180   -22.862 1.00 35.33  ? 429 ALA D N   1 
ATOM   13567 C CA  . ALA D 1 429 ? -27.751 0.314   -21.439 1.00 40.69  ? 429 ALA D CA  1 
ATOM   13568 C C   . ALA D 1 429 ? -26.846 1.351   -20.763 1.00 41.79  ? 429 ALA D C   1 
ATOM   13569 O O   . ALA D 1 429 ? -27.294 2.097   -19.893 1.00 45.03  ? 429 ALA D O   1 
ATOM   13570 C CB  . ALA D 1 429 ? -27.660 -1.045  -20.736 1.00 38.88  ? 429 ALA D CB  1 
ATOM   13571 N N   . ARG D 1 430 ? -25.575 1.391   -21.164 1.00 47.03  ? 430 ARG D N   1 
ATOM   13572 C CA  . ARG D 1 430 ? -24.594 2.269   -20.525 1.00 51.41  ? 430 ARG D CA  1 
ATOM   13573 C C   . ARG D 1 430 ? -24.895 3.748   -20.815 1.00 51.30  ? 430 ARG D C   1 
ATOM   13574 O O   . ARG D 1 430 ? -24.520 4.624   -20.035 1.00 42.35  ? 430 ARG D O   1 
ATOM   13575 C CB  . ARG D 1 430 ? -23.187 1.895   -20.975 1.00 54.36  ? 430 ARG D CB  1 
ATOM   13576 C CG  . ARG D 1 430 ? -22.726 0.595   -20.339 1.00 55.18  ? 430 ARG D CG  1 
ATOM   13577 C CD  . ARG D 1 430 ? -21.446 0.780   -19.605 1.00 57.09  ? 430 ARG D CD  1 
ATOM   13578 N NE  . ARG D 1 430 ? -20.298 0.318   -20.378 1.00 62.44  ? 430 ARG D NE  1 
ATOM   13579 C CZ  . ARG D 1 430 ? -19.038 0.606   -20.096 1.00 56.09  ? 430 ARG D CZ  1 
ATOM   13580 N NH1 . ARG D 1 430 ? -18.744 1.609   -19.269 1.00 56.63  ? 430 ARG D NH1 1 
ATOM   13581 N NH2 . ARG D 1 430 ? -18.080 -0.071  -20.688 1.00 53.64  ? 430 ARG D NH2 1 
ATOM   13582 N N   . GLN D 1 431 ? -25.580 4.019   -21.932 1.00 52.49  ? 431 GLN D N   1 
ATOM   13583 C CA  . GLN D 1 431 ? -25.908 5.391   -22.304 1.00 52.00  ? 431 GLN D CA  1 
ATOM   13584 C C   . GLN D 1 431 ? -27.178 5.871   -21.571 1.00 47.11  ? 431 GLN D C   1 
ATOM   13585 O O   . GLN D 1 431 ? -27.452 7.054   -21.552 1.00 44.40  ? 431 GLN D O   1 
ATOM   13586 C CB  . GLN D 1 431 ? -26.011 5.496   -23.824 1.00 56.94  ? 431 GLN D CB  1 
ATOM   13587 C CG  . GLN D 1 431 ? -24.649 5.485   -24.527 1.00 58.47  ? 431 GLN D CG  1 
ATOM   13588 C CD  . GLN D 1 431 ? -24.732 5.226   -26.022 1.00 66.11  ? 431 GLN D CD  1 
ATOM   13589 O OE1 . GLN D 1 431 ? -24.901 4.090   -26.474 1.00 63.83  ? 431 GLN D OE1 1 
ATOM   13590 N NE2 . GLN D 1 431 ? -24.562 6.278   -26.811 1.00 70.73  ? 431 GLN D NE2 1 
ATOM   13591 N N   . LEU D 1 432 ? -27.926 4.946   -20.938 1.00 44.04  ? 432 LEU D N   1 
ATOM   13592 C CA  . LEU D 1 432 ? -29.138 5.314   -20.211 1.00 43.77  ? 432 LEU D CA  1 
ATOM   13593 C C   . LEU D 1 432 ? -28.751 6.097   -18.967 1.00 49.47  ? 432 LEU D C   1 
ATOM   13594 O O   . LEU D 1 432 ? -27.803 5.742   -18.285 1.00 54.40  ? 432 LEU D O   1 
ATOM   13595 C CB  . LEU D 1 432 ? -29.946 4.078   -19.826 1.00 45.14  ? 432 LEU D CB  1 
ATOM   13596 C CG  . LEU D 1 432 ? -30.466 3.224   -20.976 1.00 46.64  ? 432 LEU D CG  1 
ATOM   13597 C CD1 . LEU D 1 432 ? -31.036 1.930   -20.438 1.00 46.81  ? 432 LEU D CD1 1 
ATOM   13598 C CD2 . LEU D 1 432 ? -31.492 3.979   -21.790 1.00 42.72  ? 432 LEU D CD2 1 
ATOM   13599 N N   . ARG D 1 433 ? -29.545 7.113   -18.636 1.00 53.60  ? 433 ARG D N   1 
ATOM   13600 C CA  . ARG D 1 433 ? -29.297 7.913   -17.450 1.00 61.22  ? 433 ARG D CA  1 
ATOM   13601 C C   . ARG D 1 433 ? -30.134 7.362   -16.314 1.00 59.59  ? 433 ARG D C   1 
ATOM   13602 O O   . ARG D 1 433 ? -31.068 8.004   -15.855 1.00 76.85  ? 433 ARG D O   1 
ATOM   13603 C CB  . ARG D 1 433 ? -29.564 9.386   -17.761 1.00 71.44  ? 433 ARG D CB  1 
ATOM   13604 C CG  . ARG D 1 433 ? -28.827 9.813   -19.026 1.00 88.09  ? 433 ARG D CG  1 
ATOM   13605 C CD  . ARG D 1 433 ? -29.265 11.145  -19.565 1.00 93.55  ? 433 ARG D CD  1 
ATOM   13606 N NE  . ARG D 1 433 ? -30.608 11.512  -19.110 1.00 102.57 ? 433 ARG D NE  1 
ATOM   13607 C CZ  . ARG D 1 433 ? -30.880 12.569  -18.353 1.00 109.46 ? 433 ARG D CZ  1 
ATOM   13608 N NH1 . ARG D 1 433 ? -29.903 13.367  -17.955 1.00 116.62 ? 433 ARG D NH1 1 
ATOM   13609 N NH2 . ARG D 1 433 ? -32.120 12.841  -18.020 1.00 103.41 ? 433 ARG D NH2 1 
ATOM   13610 N N   . ALA D 1 434 ? -29.797 6.145   -15.898 1.00 55.59  ? 434 ALA D N   1 
ATOM   13611 C CA  . ALA D 1 434 ? -30.553 5.423   -14.892 1.00 48.21  ? 434 ALA D CA  1 
ATOM   13612 C C   . ALA D 1 434 ? -29.582 4.681   -13.968 1.00 47.41  ? 434 ALA D C   1 
ATOM   13613 O O   . ALA D 1 434 ? -28.477 4.341   -14.368 1.00 47.90  ? 434 ALA D O   1 
ATOM   13614 C CB  . ALA D 1 434 ? -31.541 4.464   -15.569 1.00 46.10  ? 434 ALA D CB  1 
ATOM   13615 N N   . GLY D 1 435 ? -30.024 4.423   -12.739 1.00 48.37  ? 435 GLY D N   1 
ATOM   13616 C CA  . GLY D 1 435 ? -29.190 3.796   -11.731 1.00 45.22  ? 435 GLY D CA  1 
ATOM   13617 C C   . GLY D 1 435 ? -29.083 2.274   -11.929 1.00 51.26  ? 435 GLY D C   1 
ATOM   13618 O O   . GLY D 1 435 ? -28.084 1.682   -11.532 1.00 51.02  ? 435 GLY D O   1 
ATOM   13619 N N   . MET D 1 436 ? -30.152 1.643   -12.481 1.00 49.86  ? 436 MET D N   1 
ATOM   13620 C CA  . MET D 1 436 ? -30.098 0.237   -12.888 1.00 52.92  ? 436 MET D CA  1 
ATOM   13621 C C   . MET D 1 436 ? -30.749 0.032   -14.259 1.00 47.41  ? 436 MET D C   1 
ATOM   13622 O O   . MET D 1 436 ? -31.733 0.678   -14.592 1.00 38.18  ? 436 MET D O   1 
ATOM   13623 C CB  . MET D 1 436 ? -30.825 -0.679  -11.916 1.00 62.06  ? 436 MET D CB  1 
ATOM   13624 C CG  . MET D 1 436 ? -30.569 -2.190  -12.179 1.00 84.13  ? 436 MET D CG  1 
ATOM   13625 S SD  . MET D 1 436 ? -30.817 -3.206  -10.694 1.00 106.43 ? 436 MET D SD  1 
ATOM   13626 C CE  . MET D 1 436 ? -29.941 -4.728  -11.112 1.00 100.54 ? 436 MET D CE  1 
ATOM   13627 N N   . THR D 1 437 ? -30.203 -0.940  -15.007 1.00 41.83  ? 437 THR D N   1 
ATOM   13628 C CA  . THR D 1 437 ? -30.810 -1.449  -16.214 1.00 40.71  ? 437 THR D CA  1 
ATOM   13629 C C   . THR D 1 437 ? -30.779 -2.970  -16.151 1.00 40.42  ? 437 THR D C   1 
ATOM   13630 O O   . THR D 1 437 ? -29.786 -3.540  -15.760 1.00 40.04  ? 437 THR D O   1 
ATOM   13631 C CB  . THR D 1 437 ? -30.038 -0.921  -17.428 1.00 41.04  ? 437 THR D CB  1 
ATOM   13632 O OG1 . THR D 1 437 ? -29.948 0.488   -17.284 1.00 36.01  ? 437 THR D OG1 1 
ATOM   13633 C CG2 . THR D 1 437 ? -30.721 -1.240  -18.741 1.00 41.55  ? 437 THR D CG2 1 
ATOM   13634 N N   . HIS D 1 438 ? -31.886 -3.605  -16.533 1.00 41.33  ? 438 HIS D N   1 
ATOM   13635 C CA  . HIS D 1 438 ? -31.957 -5.054  -16.666 1.00 38.97  ? 438 HIS D CA  1 
ATOM   13636 C C   . HIS D 1 438 ? -31.994 -5.401  -18.148 1.00 37.46  ? 438 HIS D C   1 
ATOM   13637 O O   . HIS D 1 438 ? -32.806 -4.866  -18.890 1.00 47.28  ? 438 HIS D O   1 
ATOM   13638 C CB  . HIS D 1 438 ? -33.209 -5.602  -15.956 1.00 47.22  ? 438 HIS D CB  1 
ATOM   13639 C CG  . HIS D 1 438 ? -33.267 -5.298  -14.491 1.00 61.64  ? 438 HIS D CG  1 
ATOM   13640 N ND1 . HIS D 1 438 ? -34.252 -4.523  -13.913 1.00 69.09  ? 438 HIS D ND1 1 
ATOM   13641 C CD2 . HIS D 1 438 ? -32.454 -5.676  -13.477 1.00 67.75  ? 438 HIS D CD2 1 
ATOM   13642 C CE1 . HIS D 1 438 ? -34.030 -4.434  -12.602 1.00 68.39  ? 438 HIS D CE1 1 
ATOM   13643 N NE2 . HIS D 1 438 ? -32.940 -5.120  -12.320 1.00 65.35  ? 438 HIS D NE2 1 
ATOM   13644 N N   . VAL D 1 439 ? -31.110 -6.285  -18.573 1.00 35.32  ? 439 VAL D N   1 
ATOM   13645 C CA  . VAL D 1 439 ? -31.005 -6.656  -19.979 1.00 37.94  ? 439 VAL D CA  1 
ATOM   13646 C C   . VAL D 1 439 ? -31.562 -8.071  -20.169 1.00 39.62  ? 439 VAL D C   1 
ATOM   13647 O O   . VAL D 1 439 ? -31.088 -8.997  -19.526 1.00 43.29  ? 439 VAL D O   1 
ATOM   13648 C CB  . VAL D 1 439 ? -29.544 -6.574  -20.439 1.00 39.20  ? 439 VAL D CB  1 
ATOM   13649 C CG1 . VAL D 1 439 ? -29.343 -7.176  -21.825 1.00 41.15  ? 439 VAL D CG1 1 
ATOM   13650 C CG2 . VAL D 1 439 ? -29.020 -5.160  -20.391 1.00 38.50  ? 439 VAL D CG2 1 
ATOM   13651 N N   . ASN D 1 440 ? -32.592 -8.201  -21.050 1.00 41.17  ? 440 ASN D N   1 
ATOM   13652 C CA  . ASN D 1 440 ? -33.134 -9.494  -21.507 1.00 40.04  ? 440 ASN D CA  1 
ATOM   13653 C C   . ASN D 1 440 ? -33.604 -10.342 -20.322 1.00 43.59  ? 440 ASN D C   1 
ATOM   13654 O O   . ASN D 1 440 ? -33.515 -11.560 -20.369 1.00 43.00  ? 440 ASN D O   1 
ATOM   13655 C CB  . ASN D 1 440 ? -32.123 -10.301 -22.317 1.00 37.62  ? 440 ASN D CB  1 
ATOM   13656 C CG  . ASN D 1 440 ? -31.848 -9.730  -23.695 1.00 38.19  ? 440 ASN D CG  1 
ATOM   13657 O OD1 . ASN D 1 440 ? -32.546 -8.825  -24.167 1.00 37.19  ? 440 ASN D OD1 1 
ATOM   13658 N ND2 . ASN D 1 440 ? -30.843 -10.265 -24.363 1.00 40.51  ? 440 ASN D ND2 1 
ATOM   13659 N N   . ASP D 1 441 ? -34.156 -9.700  -19.289 1.00 48.48  ? 441 ASP D N   1 
ATOM   13660 C CA  . ASP D 1 441 ? -34.525 -10.420 -18.079 1.00 64.27  ? 441 ASP D CA  1 
ATOM   13661 C C   . ASP D 1 441 ? -35.754 -11.296 -18.346 1.00 65.91  ? 441 ASP D C   1 
ATOM   13662 O O   . ASP D 1 441 ? -36.830 -10.790 -18.588 1.00 73.67  ? 441 ASP D O   1 
ATOM   13663 C CB  . ASP D 1 441 ? -34.702 -9.485  -16.893 1.00 70.42  ? 441 ASP D CB  1 
ATOM   13664 C CG  . ASP D 1 441 ? -34.240 -10.074 -15.566 1.00 81.27  ? 441 ASP D CG  1 
ATOM   13665 O OD1 . ASP D 1 441 ? -35.074 -10.195 -14.659 1.00 90.32  ? 441 ASP D OD1 1 
ATOM   13666 O OD2 . ASP D 1 441 ? -33.053 -10.469 -15.481 1.00 82.80  ? 441 ASP D OD2 1 
ATOM   13667 N N   . ILE D 1 442 ? -35.566 -12.621 -18.235 1.00 78.37  ? 442 ILE D N   1 
ATOM   13668 C CA  . ILE D 1 442 ? -36.651 -13.592 -18.379 1.00 86.30  ? 442 ILE D CA  1 
ATOM   13669 C C   . ILE D 1 442 ? -37.318 -13.785 -17.014 1.00 94.35  ? 442 ILE D C   1 
ATOM   13670 O O   . ILE D 1 442 ? -36.644 -13.787 -15.992 1.00 96.48  ? 442 ILE D O   1 
ATOM   13671 C CB  . ILE D 1 442 ? -36.124 -14.935 -18.932 1.00 86.21  ? 442 ILE D CB  1 
ATOM   13672 C CG1 . ILE D 1 442 ? -34.915 -14.741 -19.842 1.00 90.83  ? 442 ILE D CG1 1 
ATOM   13673 C CG2 . ILE D 1 442 ? -37.237 -15.723 -19.633 1.00 89.05  ? 442 ILE D CG2 1 
ATOM   13674 C CD1 . ILE D 1 442 ? -34.226 -16.033 -20.239 1.00 92.00  ? 442 ILE D CD1 1 
ATOM   13675 N N   . PRO D 1 443 ? -38.662 -13.964 -16.953 1.00 109.17 ? 443 PRO D N   1 
ATOM   13676 C CA  . PRO D 1 443 ? -39.316 -14.463 -15.749 1.00 105.11 ? 443 PRO D CA  1 
ATOM   13677 C C   . PRO D 1 443 ? -39.430 -15.990 -15.794 1.00 99.63  ? 443 PRO D C   1 
ATOM   13678 O O   . PRO D 1 443 ? -39.877 -16.588 -14.805 1.00 89.40  ? 443 PRO D O   1 
ATOM   13679 C CB  . PRO D 1 443 ? -40.672 -13.755 -15.830 1.00 103.89 ? 443 PRO D CB  1 
ATOM   13680 C CG  . PRO D 1 443 ? -40.986 -13.739 -17.340 1.00 107.93 ? 443 PRO D CG  1 
ATOM   13681 C CD  . PRO D 1 443 ? -39.617 -13.709 -18.043 1.00 113.21 ? 443 PRO D CD  1 
ATOM   13682 N N   . GLY D 1 459 ? -29.768 -8.653  -0.797  1.00 110.20 ? 459 GLY D N   1 
ATOM   13683 C CA  . GLY D 1 459 ? -28.421 -8.204  -0.390  1.00 109.77 ? 459 GLY D CA  1 
ATOM   13684 C C   . GLY D 1 459 ? -27.427 -8.349  -1.524  1.00 114.88 ? 459 GLY D C   1 
ATOM   13685 O O   . GLY D 1 459 ? -26.466 -7.555  -1.573  1.00 110.61 ? 459 GLY D O   1 
ATOM   13686 N N   . LEU D 1 460 ? -27.647 -9.324  -2.408  1.00 122.05 ? 460 LEU D N   1 
ATOM   13687 C CA  . LEU D 1 460 ? -26.761 -9.510  -3.583  1.00 117.41 ? 460 LEU D CA  1 
ATOM   13688 C C   . LEU D 1 460 ? -26.837 -8.267  -4.477  1.00 124.65 ? 460 LEU D C   1 
ATOM   13689 O O   . LEU D 1 460 ? -25.773 -7.774  -4.879  1.00 137.15 ? 460 LEU D O   1 
ATOM   13690 C CB  . LEU D 1 460 ? -27.225 -10.749 -4.345  1.00 99.98  ? 460 LEU D CB  1 
ATOM   13691 C CG  . LEU D 1 460 ? -26.303 -11.970 -4.304  1.00 87.59  ? 460 LEU D CG  1 
ATOM   13692 C CD1 . LEU D 1 460 ? -24.856 -11.568 -4.099  1.00 85.56  ? 460 LEU D CD1 1 
ATOM   13693 C CD2 . LEU D 1 460 ? -26.760 -12.947 -3.238  1.00 81.53  ? 460 LEU D CD2 1 
ATOM   13694 N N   . GLY D 1 461 ? -28.028 -7.703  -4.670  1.00 121.23 ? 461 GLY D N   1 
ATOM   13695 C CA  . GLY D 1 461 ? -28.189 -6.593  -5.629  1.00 124.79 ? 461 GLY D CA  1 
ATOM   13696 C C   . GLY D 1 461 ? -28.916 -5.419  -5.012  1.00 130.37 ? 461 GLY D C   1 
ATOM   13697 O O   . GLY D 1 461 ? -29.558 -5.619  -3.959  1.00 136.92 ? 461 GLY D O   1 
ATOM   13698 N N   . ARG D 1 462 ? -28.760 -4.228  -5.604  1.00 128.68 ? 462 ARG D N   1 
ATOM   13699 C CA  . ARG D 1 462 ? -29.426 -3.016  -5.059  1.00 128.52 ? 462 ARG D CA  1 
ATOM   13700 C C   . ARG D 1 462 ? -28.889 -2.769  -3.642  1.00 123.31 ? 462 ARG D C   1 
ATOM   13701 O O   . ARG D 1 462 ? -27.656 -2.618  -3.505  1.00 137.26 ? 462 ARG D O   1 
ATOM   13702 C CB  . ARG D 1 462 ? -30.953 -3.151  -5.123  1.00 140.63 ? 462 ARG D CB  1 
ATOM   13703 N N   . PHE D 1 463 ? -29.765 -2.703  -2.637  1.00 118.41 ? 463 PHE D N   1 
ATOM   13704 C CA  . PHE D 1 463 ? -29.276 -2.321  -1.287  1.00 116.41 ? 463 PHE D CA  1 
ATOM   13705 C C   . PHE D 1 463 ? -28.222 -3.320  -0.869  1.00 118.17 ? 463 PHE D C   1 
ATOM   13706 O O   . PHE D 1 463 ? -28.415 -4.543  -1.037  1.00 136.82 ? 463 PHE D O   1 
ATOM   13707 C CB  . PHE D 1 463 ? -30.445 -2.324  -0.301  1.00 117.60 ? 463 PHE D CB  1 
ATOM   13708 N N   . ASN D 1 464 ? -27.130 -2.810  -0.304  1.00 105.29 ? 464 ASN D N   1 
ATOM   13709 C CA  . ASN D 1 464 ? -25.966 -3.669  0.031   1.00 100.74 ? 464 ASN D CA  1 
ATOM   13710 C C   . ASN D 1 464 ? -25.457 -3.277  1.416   1.00 86.94  ? 464 ASN D C   1 
ATOM   13711 O O   . ASN D 1 464 ? -25.777 -2.166  1.878   1.00 65.44  ? 464 ASN D O   1 
ATOM   13712 C CB  . ASN D 1 464 ? -24.859 -3.542  -1.010  1.00 98.64  ? 464 ASN D CB  1 
ATOM   13713 C CG  . ASN D 1 464 ? -24.913 -4.643  -2.042  1.00 94.74  ? 464 ASN D CG  1 
ATOM   13714 O OD1 . ASN D 1 464 ? -23.978 -5.445  -2.142  1.00 83.23  ? 464 ASN D OD1 1 
ATOM   13715 N ND2 . ASN D 1 464 ? -25.987 -4.702  -2.816  1.00 104.94 ? 464 ASN D ND2 1 
ATOM   13716 N N   . GLY D 1 465 ? -24.704 -4.168  2.052   1.00 81.69  ? 465 GLY D N   1 
ATOM   13717 C CA  . GLY D 1 465 ? -24.179 -3.871  3.392   1.00 84.90  ? 465 GLY D CA  1 
ATOM   13718 C C   . GLY D 1 465 ? -23.275 -2.664  3.339   1.00 83.94  ? 465 GLY D C   1 
ATOM   13719 O O   . GLY D 1 465 ? -23.364 -1.819  4.247   1.00 86.22  ? 465 GLY D O   1 
ATOM   13720 N N   . ASP D 1 466 ? -22.463 -2.564  2.289   1.00 75.53  ? 466 ASP D N   1 
ATOM   13721 C CA  . ASP D 1 466 ? -21.585 -1.378  2.140   1.00 66.86  ? 466 ASP D CA  1 
ATOM   13722 C C   . ASP D 1 466 ? -22.451 -0.122  2.004   1.00 61.93  ? 466 ASP D C   1 
ATOM   13723 O O   . ASP D 1 466 ? -22.126 0.882   2.663   1.00 54.44  ? 466 ASP D O   1 
ATOM   13724 C CB  . ASP D 1 466 ? -20.641 -1.575  0.967   1.00 73.73  ? 466 ASP D CB  1 
ATOM   13725 C CG  . ASP D 1 466 ? -20.411 -3.025  0.568   1.00 82.08  ? 466 ASP D CG  1 
ATOM   13726 O OD1 . ASP D 1 466 ? -19.905 -3.791  1.415   1.00 79.79  ? 466 ASP D OD1 1 
ATOM   13727 O OD2 . ASP D 1 466 ? -20.746 -3.379  -0.582  1.00 81.26  ? 466 ASP D OD2 1 
ATOM   13728 N N   . TRP D 1 467 ? -23.540 -0.190  1.232   1.00 55.26  ? 467 TRP D N   1 
ATOM   13729 C CA  . TRP D 1 467 ? -24.455 0.974   1.123   1.00 52.73  ? 467 TRP D CA  1 
ATOM   13730 C C   . TRP D 1 467 ? -25.087 1.285   2.476   1.00 46.48  ? 467 TRP D C   1 
ATOM   13731 O O   . TRP D 1 467 ? -25.140 2.471   2.850   1.00 42.57  ? 467 TRP D O   1 
ATOM   13732 C CB  . TRP D 1 467 ? -25.559 0.698   0.093   1.00 55.82  ? 467 TRP D CB  1 
ATOM   13733 C CG  . TRP D 1 467 ? -26.809 1.501   0.345   1.00 70.33  ? 467 TRP D CG  1 
ATOM   13734 C CD1 . TRP D 1 467 ? -27.034 2.793   -0.031  1.00 79.15  ? 467 TRP D CD1 1 
ATOM   13735 C CD2 . TRP D 1 467 ? -27.990 1.084   1.065   1.00 78.14  ? 467 TRP D CD2 1 
ATOM   13736 N NE1 . TRP D 1 467 ? -28.270 3.203   0.387   1.00 79.94  ? 467 TRP D NE1 1 
ATOM   13737 C CE2 . TRP D 1 467 ? -28.878 2.181   1.066   1.00 80.89  ? 467 TRP D CE2 1 
ATOM   13738 C CE3 . TRP D 1 467 ? -28.384 -0.096  1.703   1.00 77.91  ? 467 TRP D CE3 1 
ATOM   13739 C CZ2 . TRP D 1 467 ? -30.129 2.125   1.675   1.00 73.72  ? 467 TRP D CZ2 1 
ATOM   13740 C CZ3 . TRP D 1 467 ? -29.616 -0.146  2.314   1.00 74.09  ? 467 TRP D CZ3 1 
ATOM   13741 C CH2 . TRP D 1 467 ? -30.476 0.949   2.298   1.00 70.12  ? 467 TRP D CH2 1 
ATOM   13742 N N   . ALA D 1 468 ? -25.501 0.252   3.208   1.00 42.95  ? 468 ALA D N   1 
ATOM   13743 C CA  . ALA D 1 468 ? -26.233 0.480   4.472   1.00 45.06  ? 468 ALA D CA  1 
ATOM   13744 C C   . ALA D 1 468 ? -25.278 1.014   5.531   1.00 47.99  ? 468 ALA D C   1 
ATOM   13745 O O   . ALA D 1 468 ? -25.640 1.962   6.253   1.00 51.05  ? 468 ALA D O   1 
ATOM   13746 C CB  . ALA D 1 468 ? -26.878 -0.806  4.920   1.00 50.05  ? 468 ALA D CB  1 
ATOM   13747 N N   . ILE D 1 469 ? -24.095 0.410   5.622   1.00 49.81  ? 469 ILE D N   1 
ATOM   13748 C CA  . ILE D 1 469 ? -23.149 0.835   6.691   1.00 51.31  ? 469 ILE D CA  1 
ATOM   13749 C C   . ILE D 1 469 ? -22.863 2.325   6.461   1.00 50.09  ? 469 ILE D C   1 
ATOM   13750 O O   . ILE D 1 469 ? -23.006 3.105   7.413   1.00 50.50  ? 469 ILE D O   1 
ATOM   13751 C CB  . ILE D 1 469 ? -21.883 -0.040  6.707   1.00 54.63  ? 469 ILE D CB  1 
ATOM   13752 C CG1 . ILE D 1 469 ? -22.190 -1.442  7.230   1.00 59.52  ? 469 ILE D CG1 1 
ATOM   13753 C CG2 . ILE D 1 469 ? -20.766 0.621   7.511   1.00 55.10  ? 469 ILE D CG2 1 
ATOM   13754 C CD1 . ILE D 1 469 ? -21.117 -2.470  6.921   1.00 66.38  ? 469 ILE D CD1 1 
ATOM   13755 N N   . GLU D 1 470 ? -22.549 2.702   5.222   1.00 51.75  ? 470 GLU D N   1 
ATOM   13756 C CA  . GLU D 1 470 ? -22.253 4.118   4.983   1.00 53.43  ? 470 GLU D CA  1 
ATOM   13757 C C   . GLU D 1 470 ? -23.454 4.979   5.380   1.00 48.39  ? 470 GLU D C   1 
ATOM   13758 O O   . GLU D 1 470 ? -23.287 6.038   5.946   1.00 54.63  ? 470 GLU D O   1 
ATOM   13759 C CB  . GLU D 1 470 ? -21.904 4.385   3.516   1.00 58.30  ? 470 GLU D CB  1 
ATOM   13760 C CG  . GLU D 1 470 ? -20.623 3.689   3.050   1.00 73.28  ? 470 GLU D CG  1 
ATOM   13761 C CD  . GLU D 1 470 ? -19.349 4.509   3.172   1.00 76.08  ? 470 GLU D CD  1 
ATOM   13762 O OE1 . GLU D 1 470 ? -19.373 5.729   2.847   1.00 80.57  ? 470 GLU D OE1 1 
ATOM   13763 O OE2 . GLU D 1 470 ? -18.323 3.910   3.524   1.00 73.64  ? 470 GLU D OE2 1 
ATOM   13764 N N   . GLU D 1 471 ? -24.657 4.506   5.056   1.00 47.47  ? 471 GLU D N   1 
ATOM   13765 C CA  . GLU D 1 471 ? -25.866 5.300   5.183   1.00 48.52  ? 471 GLU D CA  1 
ATOM   13766 C C   . GLU D 1 471 ? -26.183 5.570   6.665   1.00 43.02  ? 471 GLU D C   1 
ATOM   13767 O O   . GLU D 1 471 ? -26.540 6.678   7.030   1.00 36.79  ? 471 GLU D O   1 
ATOM   13768 C CB  . GLU D 1 471 ? -27.026 4.579   4.509   1.00 57.89  ? 471 GLU D CB  1 
ATOM   13769 C CG  . GLU D 1 471 ? -28.310 5.402   4.454   1.00 67.23  ? 471 GLU D CG  1 
ATOM   13770 C CD  . GLU D 1 471 ? -28.471 6.143   3.149   1.00 74.97  ? 471 GLU D CD  1 
ATOM   13771 O OE1 . GLU D 1 471 ? -28.989 5.527   2.195   1.00 81.00  ? 471 GLU D OE1 1 
ATOM   13772 O OE2 . GLU D 1 471 ? -28.025 7.311   3.067   1.00 76.69  ? 471 GLU D OE2 1 
ATOM   13773 N N   . PHE D 1 472 ? -26.100 4.541   7.497   1.00 39.63  ? 472 PHE D N   1 
ATOM   13774 C CA  . PHE D 1 472 ? -26.626 4.632   8.847   1.00 40.74  ? 472 PHE D CA  1 
ATOM   13775 C C   . PHE D 1 472 ? -25.488 4.668   9.881   1.00 41.40  ? 472 PHE D C   1 
ATOM   13776 O O   . PHE D 1 472 ? -25.726 4.404   11.060  1.00 42.74  ? 472 PHE D O   1 
ATOM   13777 C CB  . PHE D 1 472 ? -27.575 3.451   9.081   1.00 40.08  ? 472 PHE D CB  1 
ATOM   13778 C CG  . PHE D 1 472 ? -28.765 3.441   8.162   1.00 34.10  ? 472 PHE D CG  1 
ATOM   13779 C CD1 . PHE D 1 472 ? -29.712 4.444   8.234   1.00 34.39  ? 472 PHE D CD1 1 
ATOM   13780 C CD2 . PHE D 1 472 ? -28.914 2.441   7.191   1.00 39.42  ? 472 PHE D CD2 1 
ATOM   13781 C CE1 . PHE D 1 472 ? -30.801 4.456   7.372   1.00 35.85  ? 472 PHE D CE1 1 
ATOM   13782 C CE2 . PHE D 1 472 ? -30.000 2.441   6.330   1.00 37.17  ? 472 PHE D CE2 1 
ATOM   13783 C CZ  . PHE D 1 472 ? -30.950 3.444   6.420   1.00 39.66  ? 472 PHE D CZ  1 
ATOM   13784 N N   . THR D 1 473 ? -24.254 4.990   9.436   1.00 37.20  ? 473 THR D N   1 
ATOM   13785 C CA  . THR D 1 473 ? -23.165 5.264   10.359  1.00 39.18  ? 473 THR D CA  1 
ATOM   13786 C C   . THR D 1 473 ? -22.500 6.569   9.974   1.00 48.02  ? 473 THR D C   1 
ATOM   13787 O O   . THR D 1 473 ? -22.702 7.089   8.871   1.00 57.29  ? 473 THR D O   1 
ATOM   13788 C CB  . THR D 1 473 ? -22.137 4.129   10.411  1.00 38.85  ? 473 THR D CB  1 
ATOM   13789 O OG1 . THR D 1 473 ? -21.569 4.050   9.110   1.00 41.60  ? 473 THR D OG1 1 
ATOM   13790 C CG2 . THR D 1 473 ? -22.720 2.803   10.894  1.00 37.87  ? 473 THR D CG2 1 
ATOM   13791 N N   . THR D 1 474 ? -21.698 7.082   10.903  1.00 48.22  ? 474 THR D N   1 
ATOM   13792 C CA  . THR D 1 474 ? -20.910 8.268   10.669  1.00 54.63  ? 474 THR D CA  1 
ATOM   13793 C C   . THR D 1 474 ? -19.488 8.023   11.182  1.00 53.39  ? 474 THR D C   1 
ATOM   13794 O O   . THR D 1 474 ? -19.272 7.190   12.072  1.00 47.33  ? 474 THR D O   1 
ATOM   13795 C CB  . THR D 1 474 ? -21.577 9.480   11.345  1.00 53.95  ? 474 THR D CB  1 
ATOM   13796 O OG1 . THR D 1 474 ? -20.726 10.564  11.016  1.00 66.15  ? 474 THR D OG1 1 
ATOM   13797 C CG2 . THR D 1 474 ? -21.701 9.333   12.854  1.00 50.88  ? 474 THR D CG2 1 
ATOM   13798 N N   . ASP D 1 475 ? -18.530 8.775   10.610  1.00 57.21  ? 475 ASP D N   1 
ATOM   13799 C CA  . ASP D 1 475 ? -17.116 8.610   10.904  1.00 60.27  ? 475 ASP D CA  1 
ATOM   13800 C C   . ASP D 1 475 ? -16.616 9.800   11.710  1.00 56.49  ? 475 ASP D C   1 
ATOM   13801 O O   . ASP D 1 475 ? -16.903 10.958  11.365  1.00 48.81  ? 475 ASP D O   1 
ATOM   13802 C CB  . ASP D 1 475 ? -16.306 8.454   9.632   1.00 61.95  ? 475 ASP D CB  1 
ATOM   13803 C CG  . ASP D 1 475 ? -16.563 7.164   8.880   1.00 66.88  ? 475 ASP D CG  1 
ATOM   13804 O OD1 . ASP D 1 475 ? -17.380 6.370   9.372   1.00 64.70  ? 475 ASP D OD1 1 
ATOM   13805 O OD2 . ASP D 1 475 ? -15.934 6.961   7.805   1.00 64.27  ? 475 ASP D OD2 1 
ATOM   13806 N N   . HIS D 1 476 ? -15.833 9.498   12.760  1.00 50.86  ? 476 HIS D N   1 
ATOM   13807 C CA  . HIS D 1 476 ? -15.166 10.517  13.557  1.00 53.95  ? 476 HIS D CA  1 
ATOM   13808 C C   . HIS D 1 476 ? -13.655 10.321  13.465  1.00 45.44  ? 476 HIS D C   1 
ATOM   13809 O O   . HIS D 1 476 ? -13.122 9.379   14.037  1.00 44.99  ? 476 HIS D O   1 
ATOM   13810 C CB  . HIS D 1 476 ? -15.635 10.456  15.022  1.00 56.71  ? 476 HIS D CB  1 
ATOM   13811 C CG  . HIS D 1 476 ? -15.257 11.663  15.845  1.00 61.56  ? 476 HIS D CG  1 
ATOM   13812 N ND1 . HIS D 1 476 ? -15.712 11.860  17.135  1.00 66.32  ? 476 HIS D ND1 1 
ATOM   13813 C CD2 . HIS D 1 476 ? -14.447 12.702  15.583  1.00 58.41  ? 476 HIS D CD2 1 
ATOM   13814 C CE1 . HIS D 1 476 ? -15.216 12.992  17.606  1.00 58.13  ? 476 HIS D CE1 1 
ATOM   13815 N NE2 . HIS D 1 476 ? -14.456 13.523  16.679  1.00 58.08  ? 476 HIS D NE2 1 
ATOM   13816 N N   . TRP D 1 477 ? -12.972 11.263  12.800  1.00 46.61  ? 477 TRP D N   1 
ATOM   13817 C CA  . TRP D 1 477 ? -11.505 11.261  12.723  1.00 54.23  ? 477 TRP D CA  1 
ATOM   13818 C C   . TRP D 1 477 ? -10.907 11.755  14.035  1.00 48.66  ? 477 TRP D C   1 
ATOM   13819 O O   . TRP D 1 477 ? -11.160 12.865  14.433  1.00 48.41  ? 477 TRP D O   1 
ATOM   13820 C CB  . TRP D 1 477 ? -11.039 12.144  11.563  1.00 60.28  ? 477 TRP D CB  1 
ATOM   13821 C CG  . TRP D 1 477 ? -11.411 11.608  10.218  1.00 67.35  ? 477 TRP D CG  1 
ATOM   13822 C CD1 . TRP D 1 477 ? -12.671 11.462  9.704   1.00 70.74  ? 477 TRP D CD1 1 
ATOM   13823 C CD2 . TRP D 1 477 ? -10.502 11.148  9.207   1.00 69.19  ? 477 TRP D CD2 1 
ATOM   13824 N NE1 . TRP D 1 477 ? -12.609 10.944  8.437   1.00 73.70  ? 477 TRP D NE1 1 
ATOM   13825 C CE2 . TRP D 1 477 ? -11.290 10.737  8.104   1.00 73.37  ? 477 TRP D CE2 1 
ATOM   13826 C CE3 . TRP D 1 477 ? -9.111  11.043  9.123   1.00 69.39  ? 477 TRP D CE3 1 
ATOM   13827 C CZ2 . TRP D 1 477 ? -10.726 10.231  6.937   1.00 71.49  ? 477 TRP D CZ2 1 
ATOM   13828 C CZ3 . TRP D 1 477 ? -8.554  10.539  7.964   1.00 74.96  ? 477 TRP D CZ3 1 
ATOM   13829 C CH2 . TRP D 1 477 ? -9.353  10.141  6.887   1.00 69.82  ? 477 TRP D CH2 1 
ATOM   13830 N N   . ILE D 1 478 ? -10.090 10.923  14.670  1.00 50.99  ? 478 ILE D N   1 
ATOM   13831 C CA  . ILE D 1 478 ? -9.403  11.290  15.912  1.00 49.40  ? 478 ILE D CA  1 
ATOM   13832 C C   . ILE D 1 478 ? -7.901  11.087  15.722  1.00 43.79  ? 478 ILE D C   1 
ATOM   13833 O O   . ILE D 1 478 ? -7.418  9.952   15.692  1.00 44.07  ? 478 ILE D O   1 
ATOM   13834 C CB  . ILE D 1 478 ? -9.943  10.464  17.107  1.00 54.37  ? 478 ILE D CB  1 
ATOM   13835 C CG1 . ILE D 1 478 ? -11.385 10.852  17.436  1.00 55.00  ? 478 ILE D CG1 1 
ATOM   13836 C CG2 . ILE D 1 478 ? -9.024  10.582  18.332  1.00 53.70  ? 478 ILE D CG2 1 
ATOM   13837 C CD1 . ILE D 1 478 ? -11.928 10.211  18.683  1.00 54.86  ? 478 ILE D CD1 1 
ATOM   13838 N N   . SER D 1 479 ? -7.171  12.195  15.643  1.00 41.78  ? 479 SER D N   1 
ATOM   13839 C CA  . SER D 1 479 ? -5.723  12.159  15.504  1.00 49.44  ? 479 SER D CA  1 
ATOM   13840 C C   . SER D 1 479 ? -5.065  12.256  16.887  1.00 50.10  ? 479 SER D C   1 
ATOM   13841 O O   . SER D 1 479 ? -5.407  13.135  17.679  1.00 46.26  ? 479 SER D O   1 
ATOM   13842 C CB  . SER D 1 479 ? -5.233  13.260  14.582  1.00 51.08  ? 479 SER D CB  1 
ATOM   13843 O OG  . SER D 1 479 ? -5.025  14.468  15.305  1.00 64.75  ? 479 SER D OG  1 
ATOM   13844 N N   . VAL D 1 480 ? -4.122  11.340  17.158  1.00 51.64  ? 480 VAL D N   1 
ATOM   13845 C CA  . VAL D 1 480 ? -3.486  11.243  18.466  1.00 57.70  ? 480 VAL D CA  1 
ATOM   13846 C C   . VAL D 1 480 ? -1.989  11.507  18.302  1.00 58.70  ? 480 VAL D C   1 
ATOM   13847 O O   . VAL D 1 480 ? -1.309  10.822  17.541  1.00 56.68  ? 480 VAL D O   1 
ATOM   13848 C CB  . VAL D 1 480 ? -3.727  9.879   19.148  1.00 56.26  ? 480 VAL D CB  1 
ATOM   13849 C CG1 . VAL D 1 480 ? -3.217  9.872   20.582  1.00 61.69  ? 480 VAL D CG1 1 
ATOM   13850 C CG2 . VAL D 1 480 ? -5.185  9.467   19.114  1.00 54.90  ? 480 VAL D CG2 1 
ATOM   13851 N N   . GLN D 1 481 ? -1.484  12.475  19.065  1.00 64.24  ? 481 GLN D N   1 
ATOM   13852 C CA  . GLN D 1 481 ? -0.083  12.876  18.996  1.00 70.64  ? 481 GLN D CA  1 
ATOM   13853 C C   . GLN D 1 481 ? 0.643   12.370  20.256  1.00 68.88  ? 481 GLN D C   1 
ATOM   13854 O O   . GLN D 1 481 ? 0.241   12.692  21.379  1.00 72.94  ? 481 GLN D O   1 
ATOM   13855 C CB  . GLN D 1 481 ? -0.054  14.404  18.789  1.00 72.48  ? 481 GLN D CB  1 
ATOM   13856 C CG  . GLN D 1 481 ? 1.347   15.034  18.714  1.00 78.98  ? 481 GLN D CG  1 
ATOM   13857 C CD  . GLN D 1 481 ? 2.315   14.282  17.818  1.00 79.58  ? 481 GLN D CD  1 
ATOM   13858 O OE1 . GLN D 1 481 ? 2.421   13.064  17.872  1.00 98.87  ? 481 GLN D OE1 1 
ATOM   13859 N NE2 . GLN D 1 481 ? 3.040   15.007  16.988  1.00 81.20  ? 481 GLN D NE2 1 
ATOM   13860 N N   . HIS D 1 482 ? 1.663   11.505  20.048  1.00 68.09  ? 482 HIS D N   1 
ATOM   13861 C CA  . HIS D 1 482 ? 2.459   10.950  21.135  1.00 74.81  ? 482 HIS D CA  1 
ATOM   13862 C C   . HIS D 1 482 ? 3.661   11.878  21.393  1.00 70.79  ? 482 HIS D C   1 
ATOM   13863 O O   . HIS D 1 482 ? 4.541   11.521  22.212  1.00 69.77  ? 482 HIS D O   1 
ATOM   13864 C CB  . HIS D 1 482 ? 2.889   9.505   20.812  1.00 79.55  ? 482 HIS D CB  1 
ATOM   13865 C CG  . HIS D 1 482 ? 1.751   8.549   20.477  1.00 84.36  ? 482 HIS D CG  1 
ATOM   13866 N ND1 . HIS D 1 482 ? 1.603   7.326   21.102  1.00 83.27  ? 482 HIS D ND1 1 
ATOM   13867 C CD2 . HIS D 1 482 ? 0.732   8.626   19.591  1.00 80.19  ? 482 HIS D CD2 1 
ATOM   13868 C CE1 . HIS D 1 482 ? 0.542   6.703   20.605  1.00 72.75  ? 482 HIS D CE1 1 
ATOM   13869 N NE2 . HIS D 1 482 ? 0.005   7.468   19.685  1.00 73.29  ? 482 HIS D NE2 1 
HETATM 13870 O O   . HOH E 2 .   ? -18.779 -14.023 -11.137 1.00 51.99  ? 501 HOH A O   1 
HETATM 13871 O O   . HOH E 2 .   ? -16.653 7.321   18.382  1.00 44.12  ? 502 HOH A O   1 
HETATM 13872 O O   . HOH E 2 .   ? -3.752  7.518   -12.217 1.00 41.42  ? 503 HOH A O   1 
HETATM 13873 O O   . HOH E 2 .   ? -28.669 -19.129 -22.325 1.00 51.13  ? 504 HOH A O   1 
HETATM 13874 O O   . HOH E 2 .   ? -30.220 -13.475 -23.283 1.00 41.87  ? 505 HOH A O   1 
HETATM 13875 O O   . HOH E 2 .   ? -16.375 12.095  30.270  1.00 55.41  ? 506 HOH A O   1 
HETATM 13876 O O   . HOH E 2 .   ? -16.684 0.408   -14.377 1.00 41.11  ? 507 HOH A O   1 
HETATM 13877 O O   . HOH E 2 .   ? -12.895 8.590   3.719   1.00 55.07  ? 508 HOH A O   1 
HETATM 13878 O O   . HOH E 2 .   ? 0.784   20.483  19.060  1.00 71.97  ? 509 HOH A O   1 
HETATM 13879 O O   . HOH E 2 .   ? -13.577 0.749   20.185  1.00 55.76  ? 510 HOH A O   1 
HETATM 13880 O O   . HOH E 2 .   ? 1.829   22.231  17.045  1.00 54.86  ? 511 HOH A O   1 
HETATM 13881 O O   . HOH E 2 .   ? 3.429   20.074  16.500  1.00 66.61  ? 512 HOH A O   1 
HETATM 13882 O O   . HOH F 2 .   ? 34.981  -6.417  3.750   1.00 46.08  ? 501 HOH B O   1 
HETATM 13883 O O   . HOH F 2 .   ? -3.948  0.123   -12.228 1.00 56.51  ? 502 HOH B O   1 
HETATM 13884 O O   . HOH F 2 .   ? 30.514  -4.781  -28.646 1.00 53.96  ? 503 HOH B O   1 
HETATM 13885 O O   . HOH F 2 .   ? 6.532   -10.399 -41.024 1.00 65.16  ? 504 HOH B O   1 
HETATM 13886 O O   . HOH F 2 .   ? 36.937  -11.021 -3.845  1.00 36.51  ? 505 HOH B O   1 
HETATM 13887 O O   . HOH F 2 .   ? 24.077  6.429   -7.556  1.00 33.66  ? 506 HOH B O   1 
HETATM 13888 O O   . HOH F 2 .   ? 30.590  3.068   -0.315  1.00 50.31  ? 507 HOH B O   1 
HETATM 13889 O O   . HOH F 2 .   ? 35.040  -17.914 -16.104 1.00 59.35  ? 508 HOH B O   1 
HETATM 13890 O O   . HOH F 2 .   ? 1.863   7.754   -8.464  1.00 63.31  ? 509 HOH B O   1 
HETATM 13891 O O   . HOH F 2 .   ? 16.600  1.907   11.582  1.00 50.12  ? 510 HOH B O   1 
HETATM 13892 O O   . HOH F 2 .   ? 25.377  -11.368 -20.371 1.00 44.77  ? 511 HOH B O   1 
HETATM 13893 O O   . HOH F 2 .   ? 30.536  2.756   -17.200 1.00 52.48  ? 512 HOH B O   1 
HETATM 13894 O O   . HOH F 2 .   ? 8.543   -9.079  -10.073 1.00 56.81  ? 513 HOH B O   1 
HETATM 13895 O O   . HOH F 2 .   ? 23.659  -1.562  1.113   1.00 36.30  ? 514 HOH B O   1 
HETATM 13896 O O   . HOH F 2 .   ? 24.069  -4.242  11.146  1.00 55.04  ? 515 HOH B O   1 
HETATM 13897 O O   . HOH F 2 .   ? 23.088  -12.113 8.826   1.00 47.61  ? 516 HOH B O   1 
HETATM 13898 O O   . HOH F 2 .   ? 21.874  -3.885  3.433   1.00 32.64  ? 517 HOH B O   1 
HETATM 13899 O O   . HOH F 2 .   ? 5.849   4.057   -19.191 1.00 52.85  ? 518 HOH B O   1 
HETATM 13900 O O   . HOH F 2 .   ? 20.553  1.244   0.165   1.00 40.29  ? 519 HOH B O   1 
HETATM 13901 O O   . HOH F 2 .   ? 12.081  -9.277  7.812   1.00 36.72  ? 520 HOH B O   1 
HETATM 13902 O O   . HOH F 2 .   ? 6.540   -9.172  9.419   1.00 47.99  ? 521 HOH B O   1 
HETATM 13903 O O   . HOH F 2 .   ? -1.045  -9.613  -3.274  1.00 47.90  ? 522 HOH B O   1 
HETATM 13904 O O   . HOH F 2 .   ? 13.286  7.931   10.672  1.00 50.71  ? 523 HOH B O   1 
HETATM 13905 O O   . HOH F 2 .   ? 18.600  1.725   -35.287 1.00 62.87  ? 524 HOH B O   1 
HETATM 13906 O O   . HOH F 2 .   ? 39.779  -12.181 -7.354  1.00 33.32  ? 525 HOH B O   1 
HETATM 13907 O O   . HOH F 2 .   ? 5.308   5.746   -16.942 1.00 44.79  ? 526 HOH B O   1 
HETATM 13908 O O   . HOH F 2 .   ? 20.977  3.906   -1.486  1.00 37.29  ? 527 HOH B O   1 
HETATM 13909 O O   . HOH F 2 .   ? -14.853 1.788   14.820  1.00 46.32  ? 528 HOH B O   1 
HETATM 13910 O O   . HOH F 2 .   ? 28.472  0.836   -8.827  1.00 56.66  ? 529 HOH B O   1 
HETATM 13911 O O   . HOH F 2 .   ? -4.709  -1.256  3.362   1.00 41.15  ? 530 HOH B O   1 
HETATM 13912 O O   . HOH F 2 .   ? 29.841  7.299   -11.317 1.00 35.80  ? 531 HOH B O   1 
HETATM 13913 O O   . HOH F 2 .   ? -2.037  0.936   9.952   1.00 43.35  ? 532 HOH B O   1 
HETATM 13914 O O   . HOH F 2 .   ? 13.992  -16.316 11.531  1.00 48.89  ? 533 HOH B O   1 
HETATM 13915 O O   . HOH F 2 .   ? 35.163  -3.878  -13.309 1.00 54.57  ? 534 HOH B O   1 
HETATM 13916 O O   . HOH F 2 .   ? -14.659 1.392   17.825  1.00 38.90  ? 535 HOH B O   1 
HETATM 13917 O O   . HOH F 2 .   ? 27.599  -12.610 -19.077 1.00 43.96  ? 536 HOH B O   1 
HETATM 13918 O O   . HOH F 2 .   ? 30.560  4.144   -7.080  1.00 56.24  ? 537 HOH B O   1 
HETATM 13919 O O   . HOH F 2 .   ? 35.786  -17.181 -19.924 1.00 58.04  ? 538 HOH B O   1 
HETATM 13920 O O   . HOH F 2 .   ? 7.639   -2.303  9.684   1.00 51.56  ? 539 HOH B O   1 
HETATM 13921 O O   . HOH F 2 .   ? 21.955  -21.529 5.065   1.00 48.70  ? 540 HOH B O   1 
HETATM 13922 O O   . HOH F 2 .   ? 28.679  6.854   -4.894  1.00 61.99  ? 541 HOH B O   1 
HETATM 13923 O O   . HOH F 2 .   ? 23.832  4.092   -0.719  1.00 35.17  ? 542 HOH B O   1 
HETATM 13924 O O   . HOH F 2 .   ? 13.046  -7.373  9.697   1.00 35.33  ? 543 HOH B O   1 
HETATM 13925 O O   . HOH F 2 .   ? 18.660  3.956   11.045  1.00 45.39  ? 544 HOH B O   1 
HETATM 13926 O O   . HOH G 2 .   ? -3.095  -28.845 39.926  1.00 39.12  ? 501 HOH C O   1 
HETATM 13927 O O   . HOH G 2 .   ? 0.760   -31.214 14.949  1.00 59.02  ? 502 HOH C O   1 
HETATM 13928 O O   . HOH G 2 .   ? -8.177  -50.608 -6.547  1.00 51.67  ? 503 HOH C O   1 
HETATM 13929 O O   . HOH G 2 .   ? 11.330  -2.102  32.978  1.00 49.76  ? 504 HOH C O   1 
HETATM 13930 O O   . HOH G 2 .   ? 0.923   -3.629  39.698  1.00 61.03  ? 505 HOH C O   1 
HETATM 13931 O O   . HOH G 2 .   ? -7.975  -39.242 -8.341  1.00 42.05  ? 506 HOH C O   1 
HETATM 13932 O O   . HOH G 2 .   ? 3.457   -41.144 3.493   1.00 59.97  ? 507 HOH C O   1 
HETATM 13933 O O   . HOH G 2 .   ? -28.130 -35.949 19.345  1.00 51.50  ? 508 HOH C O   1 
HETATM 13934 O O   . HOH G 2 .   ? -0.042  -35.157 40.513  1.00 60.42  ? 509 HOH C O   1 
HETATM 13935 O O   . HOH G 2 .   ? -4.072  -43.862 10.515  1.00 51.96  ? 510 HOH C O   1 
HETATM 13936 O O   . HOH G 2 .   ? -23.144 -40.340 17.884  1.00 35.74  ? 511 HOH C O   1 
HETATM 13937 O O   . HOH G 2 .   ? -27.035 -34.222 2.013   1.00 36.66  ? 512 HOH C O   1 
HETATM 13938 O O   . HOH G 2 .   ? -21.411 -34.352 4.307   1.00 33.93  ? 513 HOH C O   1 
HETATM 13939 O O   . HOH G 2 .   ? 9.709   -0.687  24.023  1.00 55.20  ? 514 HOH C O   1 
HETATM 13940 O O   . HOH G 2 .   ? -8.230  -41.326 20.850  1.00 39.22  ? 515 HOH C O   1 
HETATM 13941 O O   . HOH G 2 .   ? 8.014   -9.692  43.050  1.00 42.66  ? 516 HOH C O   1 
HETATM 13942 O O   . HOH G 2 .   ? -25.686 -37.643 8.561   1.00 41.29  ? 517 HOH C O   1 
HETATM 13943 O O   . HOH G 2 .   ? -14.764 -48.534 8.554   1.00 60.64  ? 518 HOH C O   1 
HETATM 13944 O O   . HOH G 2 .   ? -16.280 -49.391 11.057  1.00 53.28  ? 519 HOH C O   1 
HETATM 13945 O O   . HOH G 2 .   ? -15.575 -37.032 -2.678  1.00 39.20  ? 520 HOH C O   1 
HETATM 13946 O O   . HOH G 2 .   ? -7.912  -24.670 10.073  1.00 49.85  ? 521 HOH C O   1 
HETATM 13947 O O   . HOH G 2 .   ? -20.235 -34.823 0.557   1.00 48.93  ? 522 HOH C O   1 
HETATM 13948 O O   . HOH G 2 .   ? -8.569  -27.752 -7.536  1.00 43.52  ? 523 HOH C O   1 
HETATM 13949 O O   . HOH G 2 .   ? 14.750  -4.234  23.514  1.00 53.15  ? 524 HOH C O   1 
HETATM 13950 O O   . HOH G 2 .   ? -34.157 -27.846 3.159   1.00 54.44  ? 525 HOH C O   1 
HETATM 13951 O O   . HOH G 2 .   ? -14.212 -39.750 28.519  1.00 48.86  ? 526 HOH C O   1 
HETATM 13952 O O   . HOH G 2 .   ? -4.665  -55.372 2.714   1.00 39.56  ? 527 HOH C O   1 
HETATM 13953 O O   . HOH G 2 .   ? -16.745 -12.589 -10.093 1.00 37.48  ? 528 HOH C O   1 
HETATM 13954 O O   . HOH G 2 .   ? -17.908 -38.402 -0.242  1.00 48.77  ? 529 HOH C O   1 
HETATM 13955 O O   . HOH G 2 .   ? -8.116  -34.817 13.652  1.00 45.37  ? 530 HOH C O   1 
HETATM 13956 O O   . HOH G 2 .   ? -20.659 -17.149 -3.465  1.00 44.55  ? 531 HOH C O   1 
HETATM 13957 O O   . HOH G 2 .   ? -29.888 -18.490 2.304   1.00 42.21  ? 532 HOH C O   1 
HETATM 13958 O O   . HOH G 2 .   ? -14.835 -1.558  -32.014 1.00 61.16  ? 533 HOH C O   1 
HETATM 13959 O O   . HOH G 2 .   ? 10.715  1.673   30.450  1.00 52.08  ? 534 HOH C O   1 
HETATM 13960 O O   . HOH G 2 .   ? -14.643 -10.163 -2.989  1.00 48.66  ? 535 HOH C O   1 
HETATM 13961 O O   . HOH G 2 .   ? -2.380  -4.803  33.621  1.00 40.77  ? 536 HOH C O   1 
HETATM 13962 O O   . HOH G 2 .   ? -9.630  -14.889 40.364  1.00 55.60  ? 537 HOH C O   1 
HETATM 13963 O O   . HOH G 2 .   ? -31.768 -23.173 5.450   1.00 58.68  ? 538 HOH C O   1 
HETATM 13964 O O   . HOH G 2 .   ? -24.105 -34.869 -5.795  1.00 43.87  ? 539 HOH C O   1 
HETATM 13965 O O   . HOH G 2 .   ? -2.033  -38.717 12.512  1.00 36.51  ? 540 HOH C O   1 
HETATM 13966 O O   . HOH G 2 .   ? 13.976  -0.766  29.646  1.00 42.07  ? 541 HOH C O   1 
HETATM 13967 O O   . HOH G 2 .   ? -27.299 -34.105 21.479  1.00 43.80  ? 542 HOH C O   1 
HETATM 13968 O O   . HOH G 2 .   ? -23.412 -37.676 26.698  1.00 47.63  ? 543 HOH C O   1 
HETATM 13969 O O   . HOH G 2 .   ? -14.401 -0.084  -30.277 1.00 58.93  ? 544 HOH C O   1 
HETATM 13970 O O   . HOH G 2 .   ? -3.572  -13.958 42.101  1.00 28.70  ? 545 HOH C O   1 
HETATM 13971 O O   . HOH G 2 .   ? -7.036  -43.378 19.773  1.00 43.83  ? 546 HOH C O   1 
HETATM 13972 O O   . HOH G 2 .   ? -22.882 -32.835 -10.263 1.00 47.46  ? 547 HOH C O   1 
HETATM 13973 O O   . HOH G 2 .   ? -32.250 -15.112 2.092   1.00 49.67  ? 548 HOH C O   1 
HETATM 13974 O O   . HOH G 2 .   ? -29.555 -18.615 13.780  1.00 47.17  ? 549 HOH C O   1 
HETATM 13975 O O   . HOH G 2 .   ? -24.420 -32.192 -12.385 1.00 60.32  ? 550 HOH C O   1 
HETATM 13976 O O   . HOH G 2 .   ? -30.908 -26.654 -8.086  1.00 59.60  ? 551 HOH C O   1 
HETATM 13977 O O   . HOH G 2 .   ? -30.409 -29.079 -7.283  1.00 51.24  ? 552 HOH C O   1 
HETATM 13978 O O   . HOH G 2 .   ? -32.321 -27.875 -6.490  1.00 57.30  ? 553 HOH C O   1 
HETATM 13979 O O   . HOH H 2 .   ? -48.604 17.036  -21.409 1.00 50.14  ? 501 HOH D O   1 
HETATM 13980 O O   . HOH H 2 .   ? -47.835 7.720   -33.083 1.00 34.67  ? 502 HOH D O   1 
HETATM 13981 O O   . HOH H 2 .   ? -38.028 -5.758  -36.307 1.00 47.74  ? 503 HOH D O   1 
HETATM 13982 O O   . HOH H 2 .   ? -52.061 11.379  -18.793 1.00 31.93  ? 504 HOH D O   1 
HETATM 13983 O O   . HOH H 2 .   ? -55.471 16.940  18.267  1.00 47.44  ? 505 HOH D O   1 
HETATM 13984 O O   . HOH H 2 .   ? -32.888 8.585   -34.840 1.00 39.47  ? 506 HOH D O   1 
HETATM 13985 O O   . HOH H 2 .   ? -61.232 0.027   -15.022 1.00 36.61  ? 507 HOH D O   1 
HETATM 13986 O O   . HOH H 2 .   ? -61.362 2.750   -25.170 1.00 43.09  ? 508 HOH D O   1 
HETATM 13987 O O   . HOH H 2 .   ? -41.577 -0.515  19.678  1.00 41.38  ? 509 HOH D O   1 
HETATM 13988 O O   . HOH H 2 .   ? -49.589 -15.709 13.055  1.00 38.12  ? 510 HOH D O   1 
HETATM 13989 O O   . HOH H 2 .   ? -22.284 8.209   6.472   1.00 50.39  ? 511 HOH D O   1 
HETATM 13990 O O   . HOH H 2 .   ? -52.853 -10.065 13.612  1.00 44.67  ? 512 HOH D O   1 
HETATM 13991 O O   . HOH H 2 .   ? -18.860 -2.394  -21.098 1.00 67.27  ? 513 HOH D O   1 
HETATM 13992 O O   . HOH H 2 .   ? -51.996 7.004   3.300   1.00 45.82  ? 514 HOH D O   1 
HETATM 13993 O O   . HOH H 2 .   ? -50.436 2.406   -31.051 1.00 31.15  ? 515 HOH D O   1 
HETATM 13994 O O   . HOH H 2 .   ? -50.129 -1.934  17.814  1.00 47.00  ? 516 HOH D O   1 
HETATM 13995 O O   . HOH H 2 .   ? -38.925 -3.062  21.611  1.00 43.28  ? 517 HOH D O   1 
HETATM 13996 O O   . HOH H 2 .   ? -56.069 1.065   4.155   1.00 32.32  ? 518 HOH D O   1 
HETATM 13997 O O   . HOH H 2 .   ? -56.605 -1.374  -9.476  1.00 38.20  ? 519 HOH D O   1 
HETATM 13998 O O   . HOH H 2 .   ? -68.221 -5.646  -8.810  1.00 52.53  ? 520 HOH D O   1 
HETATM 13999 O O   . HOH H 2 .   ? -26.893 -12.514 7.196   1.00 46.74  ? 521 HOH D O   1 
HETATM 14000 O O   . HOH H 2 .   ? -68.534 -1.116  -10.817 1.00 62.28  ? 522 HOH D O   1 
HETATM 14001 O O   . HOH H 2 .   ? -44.073 14.747  6.081   1.00 51.32  ? 523 HOH D O   1 
HETATM 14002 O O   . HOH H 2 .   ? -58.879 -3.704  -26.704 1.00 54.31  ? 524 HOH D O   1 
HETATM 14003 O O   . HOH H 2 .   ? -44.280 -2.760  -36.517 1.00 40.72  ? 525 HOH D O   1 
HETATM 14004 O O   . HOH H 2 .   ? -39.000 5.983   21.473  1.00 35.86  ? 526 HOH D O   1 
HETATM 14005 O O   . HOH H 2 .   ? -57.513 -7.505  -17.524 1.00 29.30  ? 527 HOH D O   1 
HETATM 14006 O O   . HOH H 2 .   ? -57.179 10.139  -27.745 1.00 43.17  ? 528 HOH D O   1 
HETATM 14007 O O   . HOH H 2 .   ? -40.309 -3.034  18.882  1.00 32.91  ? 529 HOH D O   1 
HETATM 14008 O O   . HOH H 2 .   ? -41.693 3.004   21.786  1.00 41.25  ? 530 HOH D O   1 
HETATM 14009 O O   . HOH H 2 .   ? -54.582 -15.688 -13.014 1.00 45.71  ? 531 HOH D O   1 
HETATM 14010 O O   . HOH H 2 .   ? -49.636 7.625   -10.039 1.00 51.04  ? 532 HOH D O   1 
HETATM 14011 O O   . HOH H 2 .   ? -34.978 -14.654 3.504   1.00 33.89  ? 533 HOH D O   1 
HETATM 14012 O O   . HOH H 2 .   ? -44.846 -8.062  20.273  1.00 34.40  ? 534 HOH D O   1 
HETATM 14013 O O   . HOH H 2 .   ? -66.404 -2.182  -2.181  1.00 34.77  ? 535 HOH D O   1 
HETATM 14014 O O   . HOH H 2 .   ? -36.620 -3.127  27.083  1.00 58.77  ? 536 HOH D O   1 
HETATM 14015 O O   . HOH H 2 .   ? -39.651 -12.010 -2.229  1.00 54.28  ? 537 HOH D O   1 
HETATM 14016 O O   . HOH H 2 .   ? -64.934 3.847   -8.904  1.00 38.11  ? 538 HOH D O   1 
HETATM 14017 O O   . HOH H 2 .   ? -57.860 -5.786  0.189   1.00 30.27  ? 539 HOH D O   1 
HETATM 14018 O O   . HOH H 2 .   ? -50.808 -3.529  -33.536 1.00 51.20  ? 540 HOH D O   1 
HETATM 14019 O O   . HOH H 2 .   ? -17.084 -0.520  7.711   1.00 42.43  ? 541 HOH D O   1 
HETATM 14020 O O   . HOH H 2 .   ? -57.248 -14.621 4.674   1.00 45.37  ? 542 HOH D O   1 
HETATM 14021 O O   . HOH H 2 .   ? -51.611 16.662  -27.591 1.00 56.18  ? 543 HOH D O   1 
HETATM 14022 O O   . HOH H 2 .   ? -47.255 19.673  9.440   1.00 51.96  ? 544 HOH D O   1 
HETATM 14023 O O   . HOH H 2 .   ? -23.077 -9.607  12.421  1.00 46.04  ? 545 HOH D O   1 
HETATM 14024 O O   . HOH H 2 .   ? -52.764 -12.624 -6.151  1.00 28.83  ? 546 HOH D O   1 
HETATM 14025 O O   . HOH H 2 .   ? -57.835 2.801   5.553   1.00 37.11  ? 547 HOH D O   1 
HETATM 14026 O O   . HOH H 2 .   ? -50.794 11.752  -21.458 1.00 34.66  ? 548 HOH D O   1 
HETATM 14027 O O   . HOH H 2 .   ? -44.366 -5.446  -36.162 1.00 36.99  ? 549 HOH D O   1 
HETATM 14028 O O   . HOH H 2 .   ? -46.967 3.428   5.407   1.00 36.82  ? 550 HOH D O   1 
HETATM 14029 O O   . HOH H 2 .   ? -55.289 -15.476 6.608   1.00 55.26  ? 551 HOH D O   1 
HETATM 14030 O O   . HOH H 2 .   ? -53.173 -1.387  -3.598  1.00 45.96  ? 552 HOH D O   1 
HETATM 14031 O O   . HOH H 2 .   ? -64.062 -9.580  0.372   1.00 41.75  ? 553 HOH D O   1 
HETATM 14032 O O   . HOH H 2 .   ? -41.635 11.805  -28.771 1.00 45.99  ? 554 HOH D O   1 
HETATM 14033 O O   . HOH H 2 .   ? -31.704 1.177   -35.456 1.00 39.18  ? 555 HOH D O   1 
HETATM 14034 O O   . HOH H 2 .   ? -61.084 -1.392  -24.745 1.00 42.10  ? 556 HOH D O   1 
HETATM 14035 O O   . HOH H 2 .   ? -31.316 0.124   24.684  1.00 43.89  ? 557 HOH D O   1 
HETATM 14036 O O   . HOH H 2 .   ? -51.374 -9.361  21.100  1.00 44.98  ? 558 HOH D O   1 
HETATM 14037 O O   . HOH H 2 .   ? -61.030 -9.697  -14.844 1.00 39.04  ? 559 HOH D O   1 
HETATM 14038 O O   . HOH H 2 .   ? -36.582 -14.316 1.389   1.00 35.32  ? 560 HOH D O   1 
HETATM 14039 O O   . HOH H 2 .   ? -53.121 -4.346  -8.534  1.00 46.38  ? 561 HOH D O   1 
HETATM 14040 O O   . HOH H 2 .   ? -48.332 -3.382  -0.786  1.00 61.80  ? 562 HOH D O   1 
HETATM 14041 O O   . HOH H 2 .   ? -31.029 -12.128 2.160   1.00 44.46  ? 563 HOH D O   1 
HETATM 14042 O O   . HOH H 2 .   ? -60.970 -8.915  -27.050 1.00 51.15  ? 564 HOH D O   1 
HETATM 14043 O O   . HOH H 2 .   ? -54.113 -13.125 -14.434 1.00 41.08  ? 565 HOH D O   1 
HETATM 14044 O O   . HOH H 2 .   ? -49.009 9.508   -5.773  1.00 56.64  ? 566 HOH D O   1 
HETATM 14045 O O   . HOH H 2 .   ? -34.121 -10.459 -26.308 1.00 51.33  ? 567 HOH D O   1 
HETATM 14046 O O   . HOH H 2 .   ? -39.169 -0.377  21.018  1.00 42.22  ? 568 HOH D O   1 
HETATM 14047 O O   . HOH H 2 .   ? -61.138 -7.334  5.797   1.00 40.47  ? 569 HOH D O   1 
HETATM 14048 O O   . HOH H 2 .   ? -49.231 -16.821 10.645  1.00 30.99  ? 570 HOH D O   1 
HETATM 14049 O O   . HOH H 2 .   ? -19.884 6.573   7.394   1.00 57.16  ? 571 HOH D O   1 
HETATM 14050 O O   . HOH H 2 .   ? -47.839 -18.960 8.715   1.00 40.77  ? 572 HOH D O   1 
HETATM 14051 O O   . HOH H 2 .   ? -56.334 -5.690  16.530  1.00 44.10  ? 573 HOH D O   1 
HETATM 14052 O O   . HOH H 2 .   ? -62.461 11.420  -21.310 1.00 45.48  ? 574 HOH D O   1 
HETATM 14053 O O   . HOH H 2 .   ? -33.234 6.586   -18.548 1.00 54.53  ? 575 HOH D O   1 
HETATM 14054 O O   . HOH H 2 .   ? -47.137 -5.319  23.021  1.00 48.58  ? 576 HOH D O   1 
HETATM 14055 O O   . HOH H 2 .   ? -68.257 -1.438  -13.626 1.00 47.84  ? 577 HOH D O   1 
HETATM 14056 O O   . HOH H 2 .   ? -49.580 -4.895  22.928  1.00 51.91  ? 578 HOH D O   1 
HETATM 14057 O O   . HOH H 2 .   ? -0.420  2.555   11.348  1.00 52.57  ? 579 HOH D O   1 
HETATM 14058 O O   . HOH H 2 .   ? -29.823 -2.101  25.288  1.00 54.64  ? 580 HOH D O   1 
HETATM 14059 O O   . HOH H 2 .   ? -51.862 0.018   -32.384 1.00 43.25  ? 581 HOH D O   1 
HETATM 14060 O O   . HOH H 2 .   ? -46.276 -6.291  -37.466 1.00 38.52  ? 582 HOH D O   1 
HETATM 14061 O O   . HOH H 2 .   ? -59.934 8.667   -28.330 1.00 59.08  ? 583 HOH D O   1 
# 
