data_8ZBI
# 
_entry.id   8ZBI 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8ZBI         pdb_00008zbi 10.2210/pdb8zbi/pdb 
WWPDB D_1300047323 ?            ?                   
EMDB  EMD-39902    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-04-30 ? 
2 'EM metadata'     1 0 2025-04-30 ? 
3 FSC               1 0 2025-04-30 ? 
4 'Half map'        1 0 2025-04-30 1 
5 'Half map'        1 0 2025-04-30 2 
6 Image             1 0 2025-04-30 ? 
7 Mask              1 0 2025-04-30 1 
8 'Primary map'     1 0 2025-04-30 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1 1 'Structure model' repository 'Initial release' ? ? 
2 2 'EM metadata'     repository 'Initial release' ? ? 
3 3 FSC               repository 'Initial release' ? ? 
4 4 'Half map'        repository 'Initial release' ? ? 
5 5 'Half map'        repository 'Initial release' ? ? 
6 6 Image             repository 'Initial release' ? ? 
7 7 Mask              repository 'Initial release' ? ? 
8 8 'Primary map'     repository 'Initial release' ? ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8ZBI 
_pdbx_database_status.recvd_initial_deposition_date   2024-04-26 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Cryo-EM structure of Somatostatin receptor 3 (SSTR3) with Gi1 complex' 
_pdbx_database_related.db_id          EMD-39902 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              jhyun@ibs.re.kr 
_pdbx_contact_author.name_first         Ji-Hye 
_pdbx_contact_author.name_last          Yun 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0001-7570-369X 
# 
_audit_author.name               'Yun, J.H.' 
_audit_author.pdbx_ordinal       1 
_audit_author.identifier_ORCID   0000-0001-7570-369X 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
'The structures of SSTR3 and SSTR5 provide insights into the specificity among somatostatin receptors' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Heo, Y.'    1 ? 
primary 'Kim, Y.'    2 ? 
primary 'Cho, M.'    3 ? 
primary 'Kim, C.'    4 ? 
primary 'Ryu, B.'    5 ? 
primary 'Kang, H.J.' 6 ? 
primary 'Lee, W.'    7 ? 
primary 'Yun, J.H.'  8 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer man 'Guanine nucleotide-binding protein G(i) subunit alpha-1'           40415.031 1 ? ? ? ? 
2 polymer man 'Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1'  37728.152 1 ? ? ? ? 
3 polymer man 'Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2' 7861.143  1 ? ? ? ? 
4 polymer man scFv16                                                              31617.367 1 ? ? ? ? 
5 polymer man 'Soluble cytochrome b562,Somatostatin receptor type 3'              57656.418 1 ? ? ? ? 
6 polymer man Somatostatin-14                                                     1641.909  1 ? ? ? ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
1 'Adenylate cyclase-inhibiting G alpha protein'   
2 'Transducin beta chain 1'                        
3 'G gamma-I'                                      
5 'Cytochrome b-562,SS-3-R,SS3-R,SS3R,SST3,SSR-28' 
6 SST14                                            
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;MGCTLSAEDKAAVERSKMIDRNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEAGYSEEECKQYKAVVYSNTIQS
IIAIIRAMGRLKIDFGDSARADDARQLFVLAGAAEEGFMTAELAGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDLD
RIAQPNYIPTQQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEM
NRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICYPEYAGSNTYEEAAAYIQCQFEDLNKRKDTKEIY
THFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF
;
;MGCTLSAEDKAAVERSKMIDRNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEAGYSEEECKQYKAVVYSNTIQS
IIAIIRAMGRLKIDFGDSARADDARQLFVLAGAAEEGFMTAELAGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDLD
RIAQPNYIPTQQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEM
NRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICYPEYAGSNTYEEAAAYIQCQFEDLNKRKDTKEIY
THFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF
;
B ? 
2 'polypeptide(L)' no no 
;GPGSSGSELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQ
DGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDN
QIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFF
PNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRV
SCLGVTDDGMAVATGSWDSFLKIWN
;
;GPGSSGSELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQ
DGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDN
QIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFF
PNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRV
SCLGVTDDGMAVATGSWDSFLKIWN
;
C ? 
3 'polypeptide(L)' no no MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFCAIL 
MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFCAIL E ? 
4 'polypeptide(L)' no no 
;MLLVNQSHQGFNKEHTSKMVSAIVLYVLLAAAAHSAFADVQLVESGGGLVQPGGSRKLSCSASGFAFSSFGMHWVRQAPE
KGLEWVAYISSGSGTIYYADTVKGRFTISRDDPKNTLFLQMTSLRSEDTAMYYCVRSIYYYGSSPFDFWGQGTTLTVSSG
GGGSGGGGSGGGGSDIVMTQATSSVPVTPGESVSISCRSSKSLLHSNGNTYLYWFLQRPGQSPQLLIYRMSNLASGVPDR
FSGSGSGTAFTLTISRLEAEDVGVYYCMQHLEYPLTFGAGTKLELKAAAENLYFQG
;
;MLLVNQSHQGFNKEHTSKMVSAIVLYVLLAAAAHSAFADVQLVESGGGLVQPGGSRKLSCSASGFAFSSFGMHWVRQAPE
KGLEWVAYISSGSGTIYYADTVKGRFTISRDDPKNTLFLQMTSLRSEDTAMYYCVRSIYYYGSSPFDFWGQGTTLTVSSG
GGGSGGGGSGGGGSDIVMTQATSSVPVTPGESVSISCRSSKSLLHSNGNTYLYWFLQRPGQSPQLLIYRMSNLASGVPDR
FSGSGSGTAFTLTISRLEAEDVGVYYCMQHLEYPLTFGAGTKLELKAAAENLYFQG
;
F ? 
5 'polypeptide(L)' no no 
;ADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKATPPKLEDKSPDSPEMKDFRHGFDILVGQIDDALKLAN
EGKVKEAQAAAEQLKTTRNAYIQKYLMDMLHPSSVSTTSEPENASSAWPPDATLGNVSAGPSPAGLAVSGVLIPLVYLVV
CVVGLLGNSLVIYVVLRHTASPSVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRLVMAVDGINQFTSIFCL
TVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLPVVVFSGVPRGMSTCHMQWPEPAAAWRAGFIIYTAALG
FFGPLLVICLCYLLIVVKVRSAGRRVWAPSCQRRRRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGL
YFLVVALPYANSCANPILYGFLSYRFKQGFRRVLLRPSRRVRSQEPTVGPPEKTEEEDEEEEDGEESREGGKGKEMNGRV
SQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKSSTMRISYL
;
;ADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKATPPKLEDKSPDSPEMKDFRHGFDILVGQIDDALKLAN
EGKVKEAQAAAEQLKTTRNAYIQKYLMDMLHPSSVSTTSEPENASSAWPPDATLGNVSAGPSPAGLAVSGVLIPLVYLVV
CVVGLLGNSLVIYVVLRHTASPSVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRLVMAVDGINQFTSIFCL
TVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLPVVVFSGVPRGMSTCHMQWPEPAAAWRAGFIIYTAALG
FFGPLLVICLCYLLIVVKVRSAGRRVWAPSCQRRRRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGL
YFLVVALPYANSCANPILYGFLSYRFKQGFRRVLLRPSRRVRSQEPTVGPPEKTEEEDEEEEDGEESREGGKGKEMNGRV
SQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKSSTMRISYL
;
D ? 
6 'polypeptide(L)' no no AGCKNFFWKTFTSC AGCKNFFWKTFTSC S ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   GLY n 
1 3   CYS n 
1 4   THR n 
1 5   LEU n 
1 6   SER n 
1 7   ALA n 
1 8   GLU n 
1 9   ASP n 
1 10  LYS n 
1 11  ALA n 
1 12  ALA n 
1 13  VAL n 
1 14  GLU n 
1 15  ARG n 
1 16  SER n 
1 17  LYS n 
1 18  MET n 
1 19  ILE n 
1 20  ASP n 
1 21  ARG n 
1 22  ASN n 
1 23  LEU n 
1 24  ARG n 
1 25  GLU n 
1 26  ASP n 
1 27  GLY n 
1 28  GLU n 
1 29  LYS n 
1 30  ALA n 
1 31  ALA n 
1 32  ARG n 
1 33  GLU n 
1 34  VAL n 
1 35  LYS n 
1 36  LEU n 
1 37  LEU n 
1 38  LEU n 
1 39  LEU n 
1 40  GLY n 
1 41  ALA n 
1 42  GLY n 
1 43  GLU n 
1 44  SER n 
1 45  GLY n 
1 46  LYS n 
1 47  SER n 
1 48  THR n 
1 49  ILE n 
1 50  VAL n 
1 51  LYS n 
1 52  GLN n 
1 53  MET n 
1 54  LYS n 
1 55  ILE n 
1 56  ILE n 
1 57  HIS n 
1 58  GLU n 
1 59  ALA n 
1 60  GLY n 
1 61  TYR n 
1 62  SER n 
1 63  GLU n 
1 64  GLU n 
1 65  GLU n 
1 66  CYS n 
1 67  LYS n 
1 68  GLN n 
1 69  TYR n 
1 70  LYS n 
1 71  ALA n 
1 72  VAL n 
1 73  VAL n 
1 74  TYR n 
1 75  SER n 
1 76  ASN n 
1 77  THR n 
1 78  ILE n 
1 79  GLN n 
1 80  SER n 
1 81  ILE n 
1 82  ILE n 
1 83  ALA n 
1 84  ILE n 
1 85  ILE n 
1 86  ARG n 
1 87  ALA n 
1 88  MET n 
1 89  GLY n 
1 90  ARG n 
1 91  LEU n 
1 92  LYS n 
1 93  ILE n 
1 94  ASP n 
1 95  PHE n 
1 96  GLY n 
1 97  ASP n 
1 98  SER n 
1 99  ALA n 
1 100 ARG n 
1 101 ALA n 
1 102 ASP n 
1 103 ASP n 
1 104 ALA n 
1 105 ARG n 
1 106 GLN n 
1 107 LEU n 
1 108 PHE n 
1 109 VAL n 
1 110 LEU n 
1 111 ALA n 
1 112 GLY n 
1 113 ALA n 
1 114 ALA n 
1 115 GLU n 
1 116 GLU n 
1 117 GLY n 
1 118 PHE n 
1 119 MET n 
1 120 THR n 
1 121 ALA n 
1 122 GLU n 
1 123 LEU n 
1 124 ALA n 
1 125 GLY n 
1 126 VAL n 
1 127 ILE n 
1 128 LYS n 
1 129 ARG n 
1 130 LEU n 
1 131 TRP n 
1 132 LYS n 
1 133 ASP n 
1 134 SER n 
1 135 GLY n 
1 136 VAL n 
1 137 GLN n 
1 138 ALA n 
1 139 CYS n 
1 140 PHE n 
1 141 ASN n 
1 142 ARG n 
1 143 SER n 
1 144 ARG n 
1 145 GLU n 
1 146 TYR n 
1 147 GLN n 
1 148 LEU n 
1 149 ASN n 
1 150 ASP n 
1 151 SER n 
1 152 ALA n 
1 153 ALA n 
1 154 TYR n 
1 155 TYR n 
1 156 LEU n 
1 157 ASN n 
1 158 ASP n 
1 159 LEU n 
1 160 ASP n 
1 161 ARG n 
1 162 ILE n 
1 163 ALA n 
1 164 GLN n 
1 165 PRO n 
1 166 ASN n 
1 167 TYR n 
1 168 ILE n 
1 169 PRO n 
1 170 THR n 
1 171 GLN n 
1 172 GLN n 
1 173 ASP n 
1 174 VAL n 
1 175 LEU n 
1 176 ARG n 
1 177 THR n 
1 178 ARG n 
1 179 VAL n 
1 180 LYS n 
1 181 THR n 
1 182 THR n 
1 183 GLY n 
1 184 ILE n 
1 185 VAL n 
1 186 GLU n 
1 187 THR n 
1 188 HIS n 
1 189 PHE n 
1 190 THR n 
1 191 PHE n 
1 192 LYS n 
1 193 ASP n 
1 194 LEU n 
1 195 HIS n 
1 196 PHE n 
1 197 LYS n 
1 198 MET n 
1 199 PHE n 
1 200 ASP n 
1 201 VAL n 
1 202 GLY n 
1 203 GLY n 
1 204 GLN n 
1 205 ARG n 
1 206 SER n 
1 207 GLU n 
1 208 ARG n 
1 209 LYS n 
1 210 LYS n 
1 211 TRP n 
1 212 ILE n 
1 213 HIS n 
1 214 CYS n 
1 215 PHE n 
1 216 GLU n 
1 217 GLY n 
1 218 VAL n 
1 219 THR n 
1 220 ALA n 
1 221 ILE n 
1 222 ILE n 
1 223 PHE n 
1 224 CYS n 
1 225 VAL n 
1 226 ALA n 
1 227 LEU n 
1 228 SER n 
1 229 ASP n 
1 230 TYR n 
1 231 ASP n 
1 232 LEU n 
1 233 VAL n 
1 234 LEU n 
1 235 ALA n 
1 236 GLU n 
1 237 ASP n 
1 238 GLU n 
1 239 GLU n 
1 240 MET n 
1 241 ASN n 
1 242 ARG n 
1 243 MET n 
1 244 HIS n 
1 245 GLU n 
1 246 SER n 
1 247 MET n 
1 248 LYS n 
1 249 LEU n 
1 250 PHE n 
1 251 ASP n 
1 252 SER n 
1 253 ILE n 
1 254 CYS n 
1 255 ASN n 
1 256 ASN n 
1 257 LYS n 
1 258 TRP n 
1 259 PHE n 
1 260 THR n 
1 261 ASP n 
1 262 THR n 
1 263 SER n 
1 264 ILE n 
1 265 ILE n 
1 266 LEU n 
1 267 PHE n 
1 268 LEU n 
1 269 ASN n 
1 270 LYS n 
1 271 LYS n 
1 272 ASP n 
1 273 LEU n 
1 274 PHE n 
1 275 GLU n 
1 276 GLU n 
1 277 LYS n 
1 278 ILE n 
1 279 LYS n 
1 280 LYS n 
1 281 SER n 
1 282 PRO n 
1 283 LEU n 
1 284 THR n 
1 285 ILE n 
1 286 CYS n 
1 287 TYR n 
1 288 PRO n 
1 289 GLU n 
1 290 TYR n 
1 291 ALA n 
1 292 GLY n 
1 293 SER n 
1 294 ASN n 
1 295 THR n 
1 296 TYR n 
1 297 GLU n 
1 298 GLU n 
1 299 ALA n 
1 300 ALA n 
1 301 ALA n 
1 302 TYR n 
1 303 ILE n 
1 304 GLN n 
1 305 CYS n 
1 306 GLN n 
1 307 PHE n 
1 308 GLU n 
1 309 ASP n 
1 310 LEU n 
1 311 ASN n 
1 312 LYS n 
1 313 ARG n 
1 314 LYS n 
1 315 ASP n 
1 316 THR n 
1 317 LYS n 
1 318 GLU n 
1 319 ILE n 
1 320 TYR n 
1 321 THR n 
1 322 HIS n 
1 323 PHE n 
1 324 THR n 
1 325 CYS n 
1 326 ALA n 
1 327 THR n 
1 328 ASP n 
1 329 THR n 
1 330 LYS n 
1 331 ASN n 
1 332 VAL n 
1 333 GLN n 
1 334 PHE n 
1 335 VAL n 
1 336 PHE n 
1 337 ASP n 
1 338 ALA n 
1 339 VAL n 
1 340 THR n 
1 341 ASP n 
1 342 VAL n 
1 343 ILE n 
1 344 ILE n 
1 345 LYS n 
1 346 ASN n 
1 347 ASN n 
1 348 LEU n 
1 349 LYS n 
1 350 ASP n 
1 351 CYS n 
1 352 GLY n 
1 353 LEU n 
1 354 PHE n 
2 1   GLY n 
2 2   PRO n 
2 3   GLY n 
2 4   SER n 
2 5   SER n 
2 6   GLY n 
2 7   SER n 
2 8   GLU n 
2 9   LEU n 
2 10  ASP n 
2 11  GLN n 
2 12  LEU n 
2 13  ARG n 
2 14  GLN n 
2 15  GLU n 
2 16  ALA n 
2 17  GLU n 
2 18  GLN n 
2 19  LEU n 
2 20  LYS n 
2 21  ASN n 
2 22  GLN n 
2 23  ILE n 
2 24  ARG n 
2 25  ASP n 
2 26  ALA n 
2 27  ARG n 
2 28  LYS n 
2 29  ALA n 
2 30  CYS n 
2 31  ALA n 
2 32  ASP n 
2 33  ALA n 
2 34  THR n 
2 35  LEU n 
2 36  SER n 
2 37  GLN n 
2 38  ILE n 
2 39  THR n 
2 40  ASN n 
2 41  ASN n 
2 42  ILE n 
2 43  ASP n 
2 44  PRO n 
2 45  VAL n 
2 46  GLY n 
2 47  ARG n 
2 48  ILE n 
2 49  GLN n 
2 50  MET n 
2 51  ARG n 
2 52  THR n 
2 53  ARG n 
2 54  ARG n 
2 55  THR n 
2 56  LEU n 
2 57  ARG n 
2 58  GLY n 
2 59  HIS n 
2 60  LEU n 
2 61  ALA n 
2 62  LYS n 
2 63  ILE n 
2 64  TYR n 
2 65  ALA n 
2 66  MET n 
2 67  HIS n 
2 68  TRP n 
2 69  GLY n 
2 70  THR n 
2 71  ASP n 
2 72  SER n 
2 73  ARG n 
2 74  LEU n 
2 75  LEU n 
2 76  VAL n 
2 77  SER n 
2 78  ALA n 
2 79  SER n 
2 80  GLN n 
2 81  ASP n 
2 82  GLY n 
2 83  LYS n 
2 84  LEU n 
2 85  ILE n 
2 86  ILE n 
2 87  TRP n 
2 88  ASP n 
2 89  SER n 
2 90  TYR n 
2 91  THR n 
2 92  THR n 
2 93  ASN n 
2 94  LYS n 
2 95  VAL n 
2 96  HIS n 
2 97  ALA n 
2 98  ILE n 
2 99  PRO n 
2 100 LEU n 
2 101 ARG n 
2 102 SER n 
2 103 SER n 
2 104 TRP n 
2 105 VAL n 
2 106 MET n 
2 107 THR n 
2 108 CYS n 
2 109 ALA n 
2 110 TYR n 
2 111 ALA n 
2 112 PRO n 
2 113 SER n 
2 114 GLY n 
2 115 ASN n 
2 116 TYR n 
2 117 VAL n 
2 118 ALA n 
2 119 CYS n 
2 120 GLY n 
2 121 GLY n 
2 122 LEU n 
2 123 ASP n 
2 124 ASN n 
2 125 ILE n 
2 126 CYS n 
2 127 SER n 
2 128 ILE n 
2 129 TYR n 
2 130 ASN n 
2 131 LEU n 
2 132 LYS n 
2 133 THR n 
2 134 ARG n 
2 135 GLU n 
2 136 GLY n 
2 137 ASN n 
2 138 VAL n 
2 139 ARG n 
2 140 VAL n 
2 141 SER n 
2 142 ARG n 
2 143 GLU n 
2 144 LEU n 
2 145 ALA n 
2 146 GLY n 
2 147 HIS n 
2 148 THR n 
2 149 GLY n 
2 150 TYR n 
2 151 LEU n 
2 152 SER n 
2 153 CYS n 
2 154 CYS n 
2 155 ARG n 
2 156 PHE n 
2 157 LEU n 
2 158 ASP n 
2 159 ASP n 
2 160 ASN n 
2 161 GLN n 
2 162 ILE n 
2 163 VAL n 
2 164 THR n 
2 165 SER n 
2 166 SER n 
2 167 GLY n 
2 168 ASP n 
2 169 THR n 
2 170 THR n 
2 171 CYS n 
2 172 ALA n 
2 173 LEU n 
2 174 TRP n 
2 175 ASP n 
2 176 ILE n 
2 177 GLU n 
2 178 THR n 
2 179 GLY n 
2 180 GLN n 
2 181 GLN n 
2 182 THR n 
2 183 THR n 
2 184 THR n 
2 185 PHE n 
2 186 THR n 
2 187 GLY n 
2 188 HIS n 
2 189 THR n 
2 190 GLY n 
2 191 ASP n 
2 192 VAL n 
2 193 MET n 
2 194 SER n 
2 195 LEU n 
2 196 SER n 
2 197 LEU n 
2 198 ALA n 
2 199 PRO n 
2 200 ASP n 
2 201 THR n 
2 202 ARG n 
2 203 LEU n 
2 204 PHE n 
2 205 VAL n 
2 206 SER n 
2 207 GLY n 
2 208 ALA n 
2 209 CYS n 
2 210 ASP n 
2 211 ALA n 
2 212 SER n 
2 213 ALA n 
2 214 LYS n 
2 215 LEU n 
2 216 TRP n 
2 217 ASP n 
2 218 VAL n 
2 219 ARG n 
2 220 GLU n 
2 221 GLY n 
2 222 MET n 
2 223 CYS n 
2 224 ARG n 
2 225 GLN n 
2 226 THR n 
2 227 PHE n 
2 228 THR n 
2 229 GLY n 
2 230 HIS n 
2 231 GLU n 
2 232 SER n 
2 233 ASP n 
2 234 ILE n 
2 235 ASN n 
2 236 ALA n 
2 237 ILE n 
2 238 CYS n 
2 239 PHE n 
2 240 PHE n 
2 241 PRO n 
2 242 ASN n 
2 243 GLY n 
2 244 ASN n 
2 245 ALA n 
2 246 PHE n 
2 247 ALA n 
2 248 THR n 
2 249 GLY n 
2 250 SER n 
2 251 ASP n 
2 252 ASP n 
2 253 ALA n 
2 254 THR n 
2 255 CYS n 
2 256 ARG n 
2 257 LEU n 
2 258 PHE n 
2 259 ASP n 
2 260 LEU n 
2 261 ARG n 
2 262 ALA n 
2 263 ASP n 
2 264 GLN n 
2 265 GLU n 
2 266 LEU n 
2 267 MET n 
2 268 THR n 
2 269 TYR n 
2 270 SER n 
2 271 HIS n 
2 272 ASP n 
2 273 ASN n 
2 274 ILE n 
2 275 ILE n 
2 276 CYS n 
2 277 GLY n 
2 278 ILE n 
2 279 THR n 
2 280 SER n 
2 281 VAL n 
2 282 SER n 
2 283 PHE n 
2 284 SER n 
2 285 LYS n 
2 286 SER n 
2 287 GLY n 
2 288 ARG n 
2 289 LEU n 
2 290 LEU n 
2 291 LEU n 
2 292 ALA n 
2 293 GLY n 
2 294 TYR n 
2 295 ASP n 
2 296 ASP n 
2 297 PHE n 
2 298 ASN n 
2 299 CYS n 
2 300 ASN n 
2 301 VAL n 
2 302 TRP n 
2 303 ASP n 
2 304 ALA n 
2 305 LEU n 
2 306 LYS n 
2 307 ALA n 
2 308 ASP n 
2 309 ARG n 
2 310 ALA n 
2 311 GLY n 
2 312 VAL n 
2 313 LEU n 
2 314 ALA n 
2 315 GLY n 
2 316 HIS n 
2 317 ASP n 
2 318 ASN n 
2 319 ARG n 
2 320 VAL n 
2 321 SER n 
2 322 CYS n 
2 323 LEU n 
2 324 GLY n 
2 325 VAL n 
2 326 THR n 
2 327 ASP n 
2 328 ASP n 
2 329 GLY n 
2 330 MET n 
2 331 ALA n 
2 332 VAL n 
2 333 ALA n 
2 334 THR n 
2 335 GLY n 
2 336 SER n 
2 337 TRP n 
2 338 ASP n 
2 339 SER n 
2 340 PHE n 
2 341 LEU n 
2 342 LYS n 
2 343 ILE n 
2 344 TRP n 
2 345 ASN n 
3 1   MET n 
3 2   ALA n 
3 3   SER n 
3 4   ASN n 
3 5   ASN n 
3 6   THR n 
3 7   ALA n 
3 8   SER n 
3 9   ILE n 
3 10  ALA n 
3 11  GLN n 
3 12  ALA n 
3 13  ARG n 
3 14  LYS n 
3 15  LEU n 
3 16  VAL n 
3 17  GLU n 
3 18  GLN n 
3 19  LEU n 
3 20  LYS n 
3 21  MET n 
3 22  GLU n 
3 23  ALA n 
3 24  ASN n 
3 25  ILE n 
3 26  ASP n 
3 27  ARG n 
3 28  ILE n 
3 29  LYS n 
3 30  VAL n 
3 31  SER n 
3 32  LYS n 
3 33  ALA n 
3 34  ALA n 
3 35  ALA n 
3 36  ASP n 
3 37  LEU n 
3 38  MET n 
3 39  ALA n 
3 40  TYR n 
3 41  CYS n 
3 42  GLU n 
3 43  ALA n 
3 44  HIS n 
3 45  ALA n 
3 46  LYS n 
3 47  GLU n 
3 48  ASP n 
3 49  PRO n 
3 50  LEU n 
3 51  LEU n 
3 52  THR n 
3 53  PRO n 
3 54  VAL n 
3 55  PRO n 
3 56  ALA n 
3 57  SER n 
3 58  GLU n 
3 59  ASN n 
3 60  PRO n 
3 61  PHE n 
3 62  ARG n 
3 63  GLU n 
3 64  LYS n 
3 65  LYS n 
3 66  PHE n 
3 67  PHE n 
3 68  CYS n 
3 69  ALA n 
3 70  ILE n 
3 71  LEU n 
4 1   MET n 
4 2   LEU n 
4 3   LEU n 
4 4   VAL n 
4 5   ASN n 
4 6   GLN n 
4 7   SER n 
4 8   HIS n 
4 9   GLN n 
4 10  GLY n 
4 11  PHE n 
4 12  ASN n 
4 13  LYS n 
4 14  GLU n 
4 15  HIS n 
4 16  THR n 
4 17  SER n 
4 18  LYS n 
4 19  MET n 
4 20  VAL n 
4 21  SER n 
4 22  ALA n 
4 23  ILE n 
4 24  VAL n 
4 25  LEU n 
4 26  TYR n 
4 27  VAL n 
4 28  LEU n 
4 29  LEU n 
4 30  ALA n 
4 31  ALA n 
4 32  ALA n 
4 33  ALA n 
4 34  HIS n 
4 35  SER n 
4 36  ALA n 
4 37  PHE n 
4 38  ALA n 
4 39  ASP n 
4 40  VAL n 
4 41  GLN n 
4 42  LEU n 
4 43  VAL n 
4 44  GLU n 
4 45  SER n 
4 46  GLY n 
4 47  GLY n 
4 48  GLY n 
4 49  LEU n 
4 50  VAL n 
4 51  GLN n 
4 52  PRO n 
4 53  GLY n 
4 54  GLY n 
4 55  SER n 
4 56  ARG n 
4 57  LYS n 
4 58  LEU n 
4 59  SER n 
4 60  CYS n 
4 61  SER n 
4 62  ALA n 
4 63  SER n 
4 64  GLY n 
4 65  PHE n 
4 66  ALA n 
4 67  PHE n 
4 68  SER n 
4 69  SER n 
4 70  PHE n 
4 71  GLY n 
4 72  MET n 
4 73  HIS n 
4 74  TRP n 
4 75  VAL n 
4 76  ARG n 
4 77  GLN n 
4 78  ALA n 
4 79  PRO n 
4 80  GLU n 
4 81  LYS n 
4 82  GLY n 
4 83  LEU n 
4 84  GLU n 
4 85  TRP n 
4 86  VAL n 
4 87  ALA n 
4 88  TYR n 
4 89  ILE n 
4 90  SER n 
4 91  SER n 
4 92  GLY n 
4 93  SER n 
4 94  GLY n 
4 95  THR n 
4 96  ILE n 
4 97  TYR n 
4 98  TYR n 
4 99  ALA n 
4 100 ASP n 
4 101 THR n 
4 102 VAL n 
4 103 LYS n 
4 104 GLY n 
4 105 ARG n 
4 106 PHE n 
4 107 THR n 
4 108 ILE n 
4 109 SER n 
4 110 ARG n 
4 111 ASP n 
4 112 ASP n 
4 113 PRO n 
4 114 LYS n 
4 115 ASN n 
4 116 THR n 
4 117 LEU n 
4 118 PHE n 
4 119 LEU n 
4 120 GLN n 
4 121 MET n 
4 122 THR n 
4 123 SER n 
4 124 LEU n 
4 125 ARG n 
4 126 SER n 
4 127 GLU n 
4 128 ASP n 
4 129 THR n 
4 130 ALA n 
4 131 MET n 
4 132 TYR n 
4 133 TYR n 
4 134 CYS n 
4 135 VAL n 
4 136 ARG n 
4 137 SER n 
4 138 ILE n 
4 139 TYR n 
4 140 TYR n 
4 141 TYR n 
4 142 GLY n 
4 143 SER n 
4 144 SER n 
4 145 PRO n 
4 146 PHE n 
4 147 ASP n 
4 148 PHE n 
4 149 TRP n 
4 150 GLY n 
4 151 GLN n 
4 152 GLY n 
4 153 THR n 
4 154 THR n 
4 155 LEU n 
4 156 THR n 
4 157 VAL n 
4 158 SER n 
4 159 SER n 
4 160 GLY n 
4 161 GLY n 
4 162 GLY n 
4 163 GLY n 
4 164 SER n 
4 165 GLY n 
4 166 GLY n 
4 167 GLY n 
4 168 GLY n 
4 169 SER n 
4 170 GLY n 
4 171 GLY n 
4 172 GLY n 
4 173 GLY n 
4 174 SER n 
4 175 ASP n 
4 176 ILE n 
4 177 VAL n 
4 178 MET n 
4 179 THR n 
4 180 GLN n 
4 181 ALA n 
4 182 THR n 
4 183 SER n 
4 184 SER n 
4 185 VAL n 
4 186 PRO n 
4 187 VAL n 
4 188 THR n 
4 189 PRO n 
4 190 GLY n 
4 191 GLU n 
4 192 SER n 
4 193 VAL n 
4 194 SER n 
4 195 ILE n 
4 196 SER n 
4 197 CYS n 
4 198 ARG n 
4 199 SER n 
4 200 SER n 
4 201 LYS n 
4 202 SER n 
4 203 LEU n 
4 204 LEU n 
4 205 HIS n 
4 206 SER n 
4 207 ASN n 
4 208 GLY n 
4 209 ASN n 
4 210 THR n 
4 211 TYR n 
4 212 LEU n 
4 213 TYR n 
4 214 TRP n 
4 215 PHE n 
4 216 LEU n 
4 217 GLN n 
4 218 ARG n 
4 219 PRO n 
4 220 GLY n 
4 221 GLN n 
4 222 SER n 
4 223 PRO n 
4 224 GLN n 
4 225 LEU n 
4 226 LEU n 
4 227 ILE n 
4 228 TYR n 
4 229 ARG n 
4 230 MET n 
4 231 SER n 
4 232 ASN n 
4 233 LEU n 
4 234 ALA n 
4 235 SER n 
4 236 GLY n 
4 237 VAL n 
4 238 PRO n 
4 239 ASP n 
4 240 ARG n 
4 241 PHE n 
4 242 SER n 
4 243 GLY n 
4 244 SER n 
4 245 GLY n 
4 246 SER n 
4 247 GLY n 
4 248 THR n 
4 249 ALA n 
4 250 PHE n 
4 251 THR n 
4 252 LEU n 
4 253 THR n 
4 254 ILE n 
4 255 SER n 
4 256 ARG n 
4 257 LEU n 
4 258 GLU n 
4 259 ALA n 
4 260 GLU n 
4 261 ASP n 
4 262 VAL n 
4 263 GLY n 
4 264 VAL n 
4 265 TYR n 
4 266 TYR n 
4 267 CYS n 
4 268 MET n 
4 269 GLN n 
4 270 HIS n 
4 271 LEU n 
4 272 GLU n 
4 273 TYR n 
4 274 PRO n 
4 275 LEU n 
4 276 THR n 
4 277 PHE n 
4 278 GLY n 
4 279 ALA n 
4 280 GLY n 
4 281 THR n 
4 282 LYS n 
4 283 LEU n 
4 284 GLU n 
4 285 LEU n 
4 286 LYS n 
4 287 ALA n 
4 288 ALA n 
4 289 ALA n 
4 290 GLU n 
4 291 ASN n 
4 292 LEU n 
4 293 TYR n 
4 294 PHE n 
4 295 GLN n 
4 296 GLY n 
5 1   ALA n 
5 2   ASP n 
5 3   LEU n 
5 4   GLU n 
5 5   ASP n 
5 6   ASN n 
5 7   TRP n 
5 8   GLU n 
5 9   THR n 
5 10  LEU n 
5 11  ASN n 
5 12  ASP n 
5 13  ASN n 
5 14  LEU n 
5 15  LYS n 
5 16  VAL n 
5 17  ILE n 
5 18  GLU n 
5 19  LYS n 
5 20  ALA n 
5 21  ASP n 
5 22  ASN n 
5 23  ALA n 
5 24  ALA n 
5 25  GLN n 
5 26  VAL n 
5 27  LYS n 
5 28  ASP n 
5 29  ALA n 
5 30  LEU n 
5 31  THR n 
5 32  LYS n 
5 33  MET n 
5 34  ARG n 
5 35  ALA n 
5 36  ALA n 
5 37  ALA n 
5 38  LEU n 
5 39  ASP n 
5 40  ALA n 
5 41  GLN n 
5 42  LYS n 
5 43  ALA n 
5 44  THR n 
5 45  PRO n 
5 46  PRO n 
5 47  LYS n 
5 48  LEU n 
5 49  GLU n 
5 50  ASP n 
5 51  LYS n 
5 52  SER n 
5 53  PRO n 
5 54  ASP n 
5 55  SER n 
5 56  PRO n 
5 57  GLU n 
5 58  MET n 
5 59  LYS n 
5 60  ASP n 
5 61  PHE n 
5 62  ARG n 
5 63  HIS n 
5 64  GLY n 
5 65  PHE n 
5 66  ASP n 
5 67  ILE n 
5 68  LEU n 
5 69  VAL n 
5 70  GLY n 
5 71  GLN n 
5 72  ILE n 
5 73  ASP n 
5 74  ASP n 
5 75  ALA n 
5 76  LEU n 
5 77  LYS n 
5 78  LEU n 
5 79  ALA n 
5 80  ASN n 
5 81  GLU n 
5 82  GLY n 
5 83  LYS n 
5 84  VAL n 
5 85  LYS n 
5 86  GLU n 
5 87  ALA n 
5 88  GLN n 
5 89  ALA n 
5 90  ALA n 
5 91  ALA n 
5 92  GLU n 
5 93  GLN n 
5 94  LEU n 
5 95  LYS n 
5 96  THR n 
5 97  THR n 
5 98  ARG n 
5 99  ASN n 
5 100 ALA n 
5 101 TYR n 
5 102 ILE n 
5 103 GLN n 
5 104 LYS n 
5 105 TYR n 
5 106 LEU n 
5 107 MET n 
5 108 ASP n 
5 109 MET n 
5 110 LEU n 
5 111 HIS n 
5 112 PRO n 
5 113 SER n 
5 114 SER n 
5 115 VAL n 
5 116 SER n 
5 117 THR n 
5 118 THR n 
5 119 SER n 
5 120 GLU n 
5 121 PRO n 
5 122 GLU n 
5 123 ASN n 
5 124 ALA n 
5 125 SER n 
5 126 SER n 
5 127 ALA n 
5 128 TRP n 
5 129 PRO n 
5 130 PRO n 
5 131 ASP n 
5 132 ALA n 
5 133 THR n 
5 134 LEU n 
5 135 GLY n 
5 136 ASN n 
5 137 VAL n 
5 138 SER n 
5 139 ALA n 
5 140 GLY n 
5 141 PRO n 
5 142 SER n 
5 143 PRO n 
5 144 ALA n 
5 145 GLY n 
5 146 LEU n 
5 147 ALA n 
5 148 VAL n 
5 149 SER n 
5 150 GLY n 
5 151 VAL n 
5 152 LEU n 
5 153 ILE n 
5 154 PRO n 
5 155 LEU n 
5 156 VAL n 
5 157 TYR n 
5 158 LEU n 
5 159 VAL n 
5 160 VAL n 
5 161 CYS n 
5 162 VAL n 
5 163 VAL n 
5 164 GLY n 
5 165 LEU n 
5 166 LEU n 
5 167 GLY n 
5 168 ASN n 
5 169 SER n 
5 170 LEU n 
5 171 VAL n 
5 172 ILE n 
5 173 TYR n 
5 174 VAL n 
5 175 VAL n 
5 176 LEU n 
5 177 ARG n 
5 178 HIS n 
5 179 THR n 
5 180 ALA n 
5 181 SER n 
5 182 PRO n 
5 183 SER n 
5 184 VAL n 
5 185 THR n 
5 186 ASN n 
5 187 VAL n 
5 188 TYR n 
5 189 ILE n 
5 190 LEU n 
5 191 ASN n 
5 192 LEU n 
5 193 ALA n 
5 194 LEU n 
5 195 ALA n 
5 196 ASP n 
5 197 GLU n 
5 198 LEU n 
5 199 PHE n 
5 200 MET n 
5 201 LEU n 
5 202 GLY n 
5 203 LEU n 
5 204 PRO n 
5 205 PHE n 
5 206 LEU n 
5 207 ALA n 
5 208 ALA n 
5 209 GLN n 
5 210 ASN n 
5 211 ALA n 
5 212 LEU n 
5 213 SER n 
5 214 TYR n 
5 215 TRP n 
5 216 PRO n 
5 217 PHE n 
5 218 GLY n 
5 219 SER n 
5 220 LEU n 
5 221 MET n 
5 222 CYS n 
5 223 ARG n 
5 224 LEU n 
5 225 VAL n 
5 226 MET n 
5 227 ALA n 
5 228 VAL n 
5 229 ASP n 
5 230 GLY n 
5 231 ILE n 
5 232 ASN n 
5 233 GLN n 
5 234 PHE n 
5 235 THR n 
5 236 SER n 
5 237 ILE n 
5 238 PHE n 
5 239 CYS n 
5 240 LEU n 
5 241 THR n 
5 242 VAL n 
5 243 MET n 
5 244 SER n 
5 245 VAL n 
5 246 ASP n 
5 247 ARG n 
5 248 TYR n 
5 249 LEU n 
5 250 ALA n 
5 251 VAL n 
5 252 VAL n 
5 253 HIS n 
5 254 PRO n 
5 255 THR n 
5 256 ARG n 
5 257 SER n 
5 258 ALA n 
5 259 ARG n 
5 260 TRP n 
5 261 ARG n 
5 262 THR n 
5 263 ALA n 
5 264 PRO n 
5 265 VAL n 
5 266 ALA n 
5 267 ARG n 
5 268 THR n 
5 269 VAL n 
5 270 SER n 
5 271 ALA n 
5 272 ALA n 
5 273 VAL n 
5 274 TRP n 
5 275 VAL n 
5 276 ALA n 
5 277 SER n 
5 278 ALA n 
5 279 VAL n 
5 280 VAL n 
5 281 VAL n 
5 282 LEU n 
5 283 PRO n 
5 284 VAL n 
5 285 VAL n 
5 286 VAL n 
5 287 PHE n 
5 288 SER n 
5 289 GLY n 
5 290 VAL n 
5 291 PRO n 
5 292 ARG n 
5 293 GLY n 
5 294 MET n 
5 295 SER n 
5 296 THR n 
5 297 CYS n 
5 298 HIS n 
5 299 MET n 
5 300 GLN n 
5 301 TRP n 
5 302 PRO n 
5 303 GLU n 
5 304 PRO n 
5 305 ALA n 
5 306 ALA n 
5 307 ALA n 
5 308 TRP n 
5 309 ARG n 
5 310 ALA n 
5 311 GLY n 
5 312 PHE n 
5 313 ILE n 
5 314 ILE n 
5 315 TYR n 
5 316 THR n 
5 317 ALA n 
5 318 ALA n 
5 319 LEU n 
5 320 GLY n 
5 321 PHE n 
5 322 PHE n 
5 323 GLY n 
5 324 PRO n 
5 325 LEU n 
5 326 LEU n 
5 327 VAL n 
5 328 ILE n 
5 329 CYS n 
5 330 LEU n 
5 331 CYS n 
5 332 TYR n 
5 333 LEU n 
5 334 LEU n 
5 335 ILE n 
5 336 VAL n 
5 337 VAL n 
5 338 LYS n 
5 339 VAL n 
5 340 ARG n 
5 341 SER n 
5 342 ALA n 
5 343 GLY n 
5 344 ARG n 
5 345 ARG n 
5 346 VAL n 
5 347 TRP n 
5 348 ALA n 
5 349 PRO n 
5 350 SER n 
5 351 CYS n 
5 352 GLN n 
5 353 ARG n 
5 354 ARG n 
5 355 ARG n 
5 356 ARG n 
5 357 SER n 
5 358 GLU n 
5 359 ARG n 
5 360 ARG n 
5 361 VAL n 
5 362 THR n 
5 363 ARG n 
5 364 MET n 
5 365 VAL n 
5 366 VAL n 
5 367 ALA n 
5 368 VAL n 
5 369 VAL n 
5 370 ALA n 
5 371 LEU n 
5 372 PHE n 
5 373 VAL n 
5 374 LEU n 
5 375 CYS n 
5 376 TRP n 
5 377 MET n 
5 378 PRO n 
5 379 PHE n 
5 380 TYR n 
5 381 VAL n 
5 382 LEU n 
5 383 ASN n 
5 384 ILE n 
5 385 VAL n 
5 386 ASN n 
5 387 VAL n 
5 388 VAL n 
5 389 CYS n 
5 390 PRO n 
5 391 LEU n 
5 392 PRO n 
5 393 GLU n 
5 394 GLU n 
5 395 PRO n 
5 396 ALA n 
5 397 PHE n 
5 398 PHE n 
5 399 GLY n 
5 400 LEU n 
5 401 TYR n 
5 402 PHE n 
5 403 LEU n 
5 404 VAL n 
5 405 VAL n 
5 406 ALA n 
5 407 LEU n 
5 408 PRO n 
5 409 TYR n 
5 410 ALA n 
5 411 ASN n 
5 412 SER n 
5 413 CYS n 
5 414 ALA n 
5 415 ASN n 
5 416 PRO n 
5 417 ILE n 
5 418 LEU n 
5 419 TYR n 
5 420 GLY n 
5 421 PHE n 
5 422 LEU n 
5 423 SER n 
5 424 TYR n 
5 425 ARG n 
5 426 PHE n 
5 427 LYS n 
5 428 GLN n 
5 429 GLY n 
5 430 PHE n 
5 431 ARG n 
5 432 ARG n 
5 433 VAL n 
5 434 LEU n 
5 435 LEU n 
5 436 ARG n 
5 437 PRO n 
5 438 SER n 
5 439 ARG n 
5 440 ARG n 
5 441 VAL n 
5 442 ARG n 
5 443 SER n 
5 444 GLN n 
5 445 GLU n 
5 446 PRO n 
5 447 THR n 
5 448 VAL n 
5 449 GLY n 
5 450 PRO n 
5 451 PRO n 
5 452 GLU n 
5 453 LYS n 
5 454 THR n 
5 455 GLU n 
5 456 GLU n 
5 457 GLU n 
5 458 ASP n 
5 459 GLU n 
5 460 GLU n 
5 461 GLU n 
5 462 GLU n 
5 463 ASP n 
5 464 GLY n 
5 465 GLU n 
5 466 GLU n 
5 467 SER n 
5 468 ARG n 
5 469 GLU n 
5 470 GLY n 
5 471 GLY n 
5 472 LYS n 
5 473 GLY n 
5 474 LYS n 
5 475 GLU n 
5 476 MET n 
5 477 ASN n 
5 478 GLY n 
5 479 ARG n 
5 480 VAL n 
5 481 SER n 
5 482 GLN n 
5 483 ILE n 
5 484 THR n 
5 485 GLN n 
5 486 PRO n 
5 487 GLY n 
5 488 THR n 
5 489 SER n 
5 490 GLY n 
5 491 GLN n 
5 492 GLU n 
5 493 ARG n 
5 494 PRO n 
5 495 PRO n 
5 496 SER n 
5 497 ARG n 
5 498 VAL n 
5 499 ALA n 
5 500 SER n 
5 501 LYS n 
5 502 GLU n 
5 503 GLN n 
5 504 GLN n 
5 505 LEU n 
5 506 LEU n 
5 507 PRO n 
5 508 GLN n 
5 509 GLU n 
5 510 ALA n 
5 511 SER n 
5 512 THR n 
5 513 GLY n 
5 514 GLU n 
5 515 LYS n 
5 516 SER n 
5 517 SER n 
5 518 THR n 
5 519 MET n 
5 520 ARG n 
5 521 ILE n 
5 522 SER n 
5 523 TYR n 
5 524 LEU n 
6 1   ALA n 
6 2   GLY n 
6 3   CYS n 
6 4   LYS n 
6 5   ASN n 
6 6   PHE n 
6 7   PHE n 
6 8   TRP n 
6 9   LYS n 
6 10  THR n 
6 11  PHE n 
6 12  THR n 
6 13  SER n 
6 14  CYS n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1   354 human ? GNAI1 ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 'Spodoptera frugiperda' 
7108  ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1   345 human ? GNB1  ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 'Spodoptera frugiperda' 
7108  ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
3 1 sample 'Biological sequence' 1   71  human ? GNG2  ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 'Spodoptera frugiperda' 
7108  ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
4 1 sample 'Biological sequence' 1   296 human ? ?     ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 'Spodoptera frugiperda' 
7108  ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
5 1 sample 'Biological sequence' 1   106 human ? cybC  ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 'Spodoptera frugiperda' 
7108  ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
5 2 sample 'Biological sequence' 107 524 human ? SSTR3 ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 'Spodoptera frugiperda' 
7108  ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
6 1 sample 'Biological sequence' 1   14  human ? SST   ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 'synthetic construct'   
32630 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1    ?   ?   ?   B . n 
A 1 2   GLY 2   2    ?   ?   ?   B . n 
A 1 3   CYS 3   3    ?   ?   ?   B . n 
A 1 4   THR 4   4    ?   ?   ?   B . n 
A 1 5   LEU 5   5    5   LEU LEU B . n 
A 1 6   SER 6   6    6   SER SER B . n 
A 1 7   ALA 7   7    7   ALA ALA B . n 
A 1 8   GLU 8   8    8   GLU GLU B . n 
A 1 9   ASP 9   9    9   ASP ASP B . n 
A 1 10  LYS 10  10   10  LYS LYS B . n 
A 1 11  ALA 11  11   11  ALA ALA B . n 
A 1 12  ALA 12  12   12  ALA ALA B . n 
A 1 13  VAL 13  13   13  VAL VAL B . n 
A 1 14  GLU 14  14   14  GLU GLU B . n 
A 1 15  ARG 15  15   15  ARG ARG B . n 
A 1 16  SER 16  16   16  SER SER B . n 
A 1 17  LYS 17  17   17  LYS LYS B . n 
A 1 18  MET 18  18   18  MET MET B . n 
A 1 19  ILE 19  19   19  ILE ILE B . n 
A 1 20  ASP 20  20   20  ASP ASP B . n 
A 1 21  ARG 21  21   21  ARG ARG B . n 
A 1 22  ASN 22  22   22  ASN ASN B . n 
A 1 23  LEU 23  23   23  LEU LEU B . n 
A 1 24  ARG 24  24   24  ARG ARG B . n 
A 1 25  GLU 25  25   25  GLU GLU B . n 
A 1 26  ASP 26  26   26  ASP ASP B . n 
A 1 27  GLY 27  27   27  GLY GLY B . n 
A 1 28  GLU 28  28   28  GLU GLU B . n 
A 1 29  LYS 29  29   29  LYS LYS B . n 
A 1 30  ALA 30  30   30  ALA ALA B . n 
A 1 31  ALA 31  31   31  ALA ALA B . n 
A 1 32  ARG 32  32   32  ARG ARG B . n 
A 1 33  GLU 33  33   33  GLU GLU B . n 
A 1 34  VAL 34  34   34  VAL VAL B . n 
A 1 35  LYS 35  35   35  LYS LYS B . n 
A 1 36  LEU 36  36   36  LEU LEU B . n 
A 1 37  LEU 37  37   37  LEU LEU B . n 
A 1 38  LEU 38  38   38  LEU LEU B . n 
A 1 39  LEU 39  39   39  LEU LEU B . n 
A 1 40  GLY 40  40   ?   ?   ?   B . n 
A 1 41  ALA 41  41   ?   ?   ?   B . n 
A 1 42  GLY 42  42   ?   ?   ?   B . n 
A 1 43  GLU 43  43   ?   ?   ?   B . n 
A 1 44  SER 44  44   ?   ?   ?   B . n 
A 1 45  GLY 45  45   ?   ?   ?   B . n 
A 1 46  LYS 46  46   ?   ?   ?   B . n 
A 1 47  SER 47  47   ?   ?   ?   B . n 
A 1 48  THR 48  48   ?   ?   ?   B . n 
A 1 49  ILE 49  49   ?   ?   ?   B . n 
A 1 50  VAL 50  50   ?   ?   ?   B . n 
A 1 51  LYS 51  51   ?   ?   ?   B . n 
A 1 52  GLN 52  52   ?   ?   ?   B . n 
A 1 53  MET 53  53   ?   ?   ?   B . n 
A 1 54  LYS 54  54   ?   ?   ?   B . n 
A 1 55  ILE 55  55   ?   ?   ?   B . n 
A 1 56  ILE 56  56   ?   ?   ?   B . n 
A 1 57  HIS 57  57   ?   ?   ?   B . n 
A 1 58  GLU 58  58   ?   ?   ?   B . n 
A 1 59  ALA 59  59   ?   ?   ?   B . n 
A 1 60  GLY 60  60   ?   ?   ?   B . n 
A 1 61  TYR 61  61   ?   ?   ?   B . n 
A 1 62  SER 62  62   ?   ?   ?   B . n 
A 1 63  GLU 63  63   ?   ?   ?   B . n 
A 1 64  GLU 64  64   ?   ?   ?   B . n 
A 1 65  GLU 65  65   ?   ?   ?   B . n 
A 1 66  CYS 66  66   ?   ?   ?   B . n 
A 1 67  LYS 67  67   ?   ?   ?   B . n 
A 1 68  GLN 68  68   ?   ?   ?   B . n 
A 1 69  TYR 69  69   ?   ?   ?   B . n 
A 1 70  LYS 70  70   ?   ?   ?   B . n 
A 1 71  ALA 71  71   ?   ?   ?   B . n 
A 1 72  VAL 72  72   ?   ?   ?   B . n 
A 1 73  VAL 73  73   ?   ?   ?   B . n 
A 1 74  TYR 74  74   ?   ?   ?   B . n 
A 1 75  SER 75  75   ?   ?   ?   B . n 
A 1 76  ASN 76  76   ?   ?   ?   B . n 
A 1 77  THR 77  77   ?   ?   ?   B . n 
A 1 78  ILE 78  78   ?   ?   ?   B . n 
A 1 79  GLN 79  79   ?   ?   ?   B . n 
A 1 80  SER 80  80   ?   ?   ?   B . n 
A 1 81  ILE 81  81   ?   ?   ?   B . n 
A 1 82  ILE 82  82   ?   ?   ?   B . n 
A 1 83  ALA 83  83   ?   ?   ?   B . n 
A 1 84  ILE 84  84   ?   ?   ?   B . n 
A 1 85  ILE 85  85   ?   ?   ?   B . n 
A 1 86  ARG 86  86   ?   ?   ?   B . n 
A 1 87  ALA 87  87   ?   ?   ?   B . n 
A 1 88  MET 88  88   ?   ?   ?   B . n 
A 1 89  GLY 89  89   ?   ?   ?   B . n 
A 1 90  ARG 90  90   ?   ?   ?   B . n 
A 1 91  LEU 91  91   ?   ?   ?   B . n 
A 1 92  LYS 92  92   ?   ?   ?   B . n 
A 1 93  ILE 93  93   ?   ?   ?   B . n 
A 1 94  ASP 94  94   ?   ?   ?   B . n 
A 1 95  PHE 95  95   ?   ?   ?   B . n 
A 1 96  GLY 96  96   ?   ?   ?   B . n 
A 1 97  ASP 97  97   ?   ?   ?   B . n 
A 1 98  SER 98  98   ?   ?   ?   B . n 
A 1 99  ALA 99  99   ?   ?   ?   B . n 
A 1 100 ARG 100 100  ?   ?   ?   B . n 
A 1 101 ALA 101 101  ?   ?   ?   B . n 
A 1 102 ASP 102 102  ?   ?   ?   B . n 
A 1 103 ASP 103 103  ?   ?   ?   B . n 
A 1 104 ALA 104 104  ?   ?   ?   B . n 
A 1 105 ARG 105 105  ?   ?   ?   B . n 
A 1 106 GLN 106 106  ?   ?   ?   B . n 
A 1 107 LEU 107 107  ?   ?   ?   B . n 
A 1 108 PHE 108 108  ?   ?   ?   B . n 
A 1 109 VAL 109 109  ?   ?   ?   B . n 
A 1 110 LEU 110 110  ?   ?   ?   B . n 
A 1 111 ALA 111 111  ?   ?   ?   B . n 
A 1 112 GLY 112 112  ?   ?   ?   B . n 
A 1 113 ALA 113 113  ?   ?   ?   B . n 
A 1 114 ALA 114 114  ?   ?   ?   B . n 
A 1 115 GLU 115 115  ?   ?   ?   B . n 
A 1 116 GLU 116 116  ?   ?   ?   B . n 
A 1 117 GLY 117 117  ?   ?   ?   B . n 
A 1 118 PHE 118 118  ?   ?   ?   B . n 
A 1 119 MET 119 119  ?   ?   ?   B . n 
A 1 120 THR 120 120  ?   ?   ?   B . n 
A 1 121 ALA 121 121  ?   ?   ?   B . n 
A 1 122 GLU 122 122  ?   ?   ?   B . n 
A 1 123 LEU 123 123  ?   ?   ?   B . n 
A 1 124 ALA 124 124  ?   ?   ?   B . n 
A 1 125 GLY 125 125  ?   ?   ?   B . n 
A 1 126 VAL 126 126  ?   ?   ?   B . n 
A 1 127 ILE 127 127  ?   ?   ?   B . n 
A 1 128 LYS 128 128  ?   ?   ?   B . n 
A 1 129 ARG 129 129  ?   ?   ?   B . n 
A 1 130 LEU 130 130  ?   ?   ?   B . n 
A 1 131 TRP 131 131  ?   ?   ?   B . n 
A 1 132 LYS 132 132  ?   ?   ?   B . n 
A 1 133 ASP 133 133  ?   ?   ?   B . n 
A 1 134 SER 134 134  ?   ?   ?   B . n 
A 1 135 GLY 135 135  ?   ?   ?   B . n 
A 1 136 VAL 136 136  ?   ?   ?   B . n 
A 1 137 GLN 137 137  ?   ?   ?   B . n 
A 1 138 ALA 138 138  ?   ?   ?   B . n 
A 1 139 CYS 139 139  ?   ?   ?   B . n 
A 1 140 PHE 140 140  ?   ?   ?   B . n 
A 1 141 ASN 141 141  ?   ?   ?   B . n 
A 1 142 ARG 142 142  ?   ?   ?   B . n 
A 1 143 SER 143 143  ?   ?   ?   B . n 
A 1 144 ARG 144 144  ?   ?   ?   B . n 
A 1 145 GLU 145 145  ?   ?   ?   B . n 
A 1 146 TYR 146 146  ?   ?   ?   B . n 
A 1 147 GLN 147 147  ?   ?   ?   B . n 
A 1 148 LEU 148 148  ?   ?   ?   B . n 
A 1 149 ASN 149 149  ?   ?   ?   B . n 
A 1 150 ASP 150 150  ?   ?   ?   B . n 
A 1 151 SER 151 151  ?   ?   ?   B . n 
A 1 152 ALA 152 152  ?   ?   ?   B . n 
A 1 153 ALA 153 153  ?   ?   ?   B . n 
A 1 154 TYR 154 154  ?   ?   ?   B . n 
A 1 155 TYR 155 155  ?   ?   ?   B . n 
A 1 156 LEU 156 156  ?   ?   ?   B . n 
A 1 157 ASN 157 157  ?   ?   ?   B . n 
A 1 158 ASP 158 158  ?   ?   ?   B . n 
A 1 159 LEU 159 159  ?   ?   ?   B . n 
A 1 160 ASP 160 160  ?   ?   ?   B . n 
A 1 161 ARG 161 161  ?   ?   ?   B . n 
A 1 162 ILE 162 162  ?   ?   ?   B . n 
A 1 163 ALA 163 163  ?   ?   ?   B . n 
A 1 164 GLN 164 164  ?   ?   ?   B . n 
A 1 165 PRO 165 165  ?   ?   ?   B . n 
A 1 166 ASN 166 166  ?   ?   ?   B . n 
A 1 167 TYR 167 167  ?   ?   ?   B . n 
A 1 168 ILE 168 168  ?   ?   ?   B . n 
A 1 169 PRO 169 169  ?   ?   ?   B . n 
A 1 170 THR 170 170  ?   ?   ?   B . n 
A 1 171 GLN 171 171  ?   ?   ?   B . n 
A 1 172 GLN 172 172  ?   ?   ?   B . n 
A 1 173 ASP 173 173  ?   ?   ?   B . n 
A 1 174 VAL 174 174  ?   ?   ?   B . n 
A 1 175 LEU 175 175  ?   ?   ?   B . n 
A 1 176 ARG 176 176  ?   ?   ?   B . n 
A 1 177 THR 177 177  ?   ?   ?   B . n 
A 1 178 ARG 178 178  ?   ?   ?   B . n 
A 1 179 VAL 179 179  ?   ?   ?   B . n 
A 1 180 LYS 180 180  ?   ?   ?   B . n 
A 1 181 THR 181 181  ?   ?   ?   B . n 
A 1 182 THR 182 182  ?   ?   ?   B . n 
A 1 183 GLY 183 183  ?   ?   ?   B . n 
A 1 184 ILE 184 184  184 ILE ILE B . n 
A 1 185 VAL 185 185  185 VAL VAL B . n 
A 1 186 GLU 186 186  186 GLU GLU B . n 
A 1 187 THR 187 187  187 THR THR B . n 
A 1 188 HIS 188 188  188 HIS HIS B . n 
A 1 189 PHE 189 189  189 PHE PHE B . n 
A 1 190 THR 190 190  190 THR THR B . n 
A 1 191 PHE 191 191  191 PHE PHE B . n 
A 1 192 LYS 192 192  192 LYS LYS B . n 
A 1 193 ASP 193 193  193 ASP ASP B . n 
A 1 194 LEU 194 194  194 LEU LEU B . n 
A 1 195 HIS 195 195  195 HIS HIS B . n 
A 1 196 PHE 196 196  196 PHE PHE B . n 
A 1 197 LYS 197 197  197 LYS LYS B . n 
A 1 198 MET 198 198  198 MET MET B . n 
A 1 199 PHE 199 199  199 PHE PHE B . n 
A 1 200 ASP 200 200  200 ASP ASP B . n 
A 1 201 VAL 201 201  201 VAL VAL B . n 
A 1 202 GLY 202 202  ?   ?   ?   B . n 
A 1 203 GLY 203 203  ?   ?   ?   B . n 
A 1 204 GLN 204 204  ?   ?   ?   B . n 
A 1 205 ARG 205 205  ?   ?   ?   B . n 
A 1 206 SER 206 206  206 SER SER B . n 
A 1 207 GLU 207 207  207 GLU GLU B . n 
A 1 208 ARG 208 208  208 ARG ARG B . n 
A 1 209 LYS 209 209  209 LYS LYS B . n 
A 1 210 LYS 210 210  210 LYS LYS B . n 
A 1 211 TRP 211 211  211 TRP TRP B . n 
A 1 212 ILE 212 212  212 ILE ILE B . n 
A 1 213 HIS 213 213  213 HIS HIS B . n 
A 1 214 CYS 214 214  214 CYS CYS B . n 
A 1 215 PHE 215 215  215 PHE PHE B . n 
A 1 216 GLU 216 216  216 GLU GLU B . n 
A 1 217 GLY 217 217  217 GLY GLY B . n 
A 1 218 VAL 218 218  218 VAL VAL B . n 
A 1 219 THR 219 219  219 THR THR B . n 
A 1 220 ALA 220 220  220 ALA ALA B . n 
A 1 221 ILE 221 221  221 ILE ILE B . n 
A 1 222 ILE 222 222  222 ILE ILE B . n 
A 1 223 PHE 223 223  223 PHE PHE B . n 
A 1 224 CYS 224 224  224 CYS CYS B . n 
A 1 225 VAL 225 225  ?   ?   ?   B . n 
A 1 226 ALA 226 226  ?   ?   ?   B . n 
A 1 227 LEU 227 227  ?   ?   ?   B . n 
A 1 228 SER 228 228  ?   ?   ?   B . n 
A 1 229 ASP 229 229  ?   ?   ?   B . n 
A 1 230 TYR 230 230  ?   ?   ?   B . n 
A 1 231 ASP 231 231  ?   ?   ?   B . n 
A 1 232 LEU 232 232  ?   ?   ?   B . n 
A 1 233 VAL 233 233  ?   ?   ?   B . n 
A 1 234 LEU 234 234  ?   ?   ?   B . n 
A 1 235 ALA 235 235  ?   ?   ?   B . n 
A 1 236 GLU 236 236  ?   ?   ?   B . n 
A 1 237 ASP 237 237  ?   ?   ?   B . n 
A 1 238 GLU 238 238  ?   ?   ?   B . n 
A 1 239 GLU 239 239  ?   ?   ?   B . n 
A 1 240 MET 240 240  ?   ?   ?   B . n 
A 1 241 ASN 241 241  ?   ?   ?   B . n 
A 1 242 ARG 242 242  ?   ?   ?   B . n 
A 1 243 MET 243 243  ?   ?   ?   B . n 
A 1 244 HIS 244 244  ?   ?   ?   B . n 
A 1 245 GLU 245 245  ?   ?   ?   B . n 
A 1 246 SER 246 246  ?   ?   ?   B . n 
A 1 247 MET 247 247  ?   ?   ?   B . n 
A 1 248 LYS 248 248  ?   ?   ?   B . n 
A 1 249 LEU 249 249  ?   ?   ?   B . n 
A 1 250 PHE 250 250  ?   ?   ?   B . n 
A 1 251 ASP 251 251  ?   ?   ?   B . n 
A 1 252 SER 252 252  ?   ?   ?   B . n 
A 1 253 ILE 253 253  ?   ?   ?   B . n 
A 1 254 CYS 254 254  ?   ?   ?   B . n 
A 1 255 ASN 255 255  ?   ?   ?   B . n 
A 1 256 ASN 256 256  ?   ?   ?   B . n 
A 1 257 LYS 257 257  ?   ?   ?   B . n 
A 1 258 TRP 258 258  ?   ?   ?   B . n 
A 1 259 PHE 259 259  ?   ?   ?   B . n 
A 1 260 THR 260 260  ?   ?   ?   B . n 
A 1 261 ASP 261 261  ?   ?   ?   B . n 
A 1 262 THR 262 262  262 THR THR B . n 
A 1 263 SER 263 263  263 SER SER B . n 
A 1 264 ILE 264 264  264 ILE ILE B . n 
A 1 265 ILE 265 265  265 ILE ILE B . n 
A 1 266 LEU 266 266  266 LEU LEU B . n 
A 1 267 PHE 267 267  267 PHE PHE B . n 
A 1 268 LEU 268 268  ?   ?   ?   B . n 
A 1 269 ASN 269 269  ?   ?   ?   B . n 
A 1 270 LYS 270 270  ?   ?   ?   B . n 
A 1 271 LYS 271 271  ?   ?   ?   B . n 
A 1 272 ASP 272 272  ?   ?   ?   B . n 
A 1 273 LEU 273 273  ?   ?   ?   B . n 
A 1 274 PHE 274 274  ?   ?   ?   B . n 
A 1 275 GLU 275 275  ?   ?   ?   B . n 
A 1 276 GLU 276 276  ?   ?   ?   B . n 
A 1 277 LYS 277 277  ?   ?   ?   B . n 
A 1 278 ILE 278 278  ?   ?   ?   B . n 
A 1 279 LYS 279 279  ?   ?   ?   B . n 
A 1 280 LYS 280 280  ?   ?   ?   B . n 
A 1 281 SER 281 281  ?   ?   ?   B . n 
A 1 282 PRO 282 282  ?   ?   ?   B . n 
A 1 283 LEU 283 283  ?   ?   ?   B . n 
A 1 284 THR 284 284  ?   ?   ?   B . n 
A 1 285 ILE 285 285  ?   ?   ?   B . n 
A 1 286 CYS 286 286  ?   ?   ?   B . n 
A 1 287 TYR 287 287  ?   ?   ?   B . n 
A 1 288 PRO 288 288  ?   ?   ?   B . n 
A 1 289 GLU 289 289  ?   ?   ?   B . n 
A 1 290 TYR 290 290  ?   ?   ?   B . n 
A 1 291 ALA 291 291  ?   ?   ?   B . n 
A 1 292 GLY 292 292  ?   ?   ?   B . n 
A 1 293 SER 293 293  ?   ?   ?   B . n 
A 1 294 ASN 294 294  ?   ?   ?   B . n 
A 1 295 THR 295 295  ?   ?   ?   B . n 
A 1 296 TYR 296 296  ?   ?   ?   B . n 
A 1 297 GLU 297 297  ?   ?   ?   B . n 
A 1 298 GLU 298 298  ?   ?   ?   B . n 
A 1 299 ALA 299 299  ?   ?   ?   B . n 
A 1 300 ALA 300 300  ?   ?   ?   B . n 
A 1 301 ALA 301 301  ?   ?   ?   B . n 
A 1 302 TYR 302 302  ?   ?   ?   B . n 
A 1 303 ILE 303 303  ?   ?   ?   B . n 
A 1 304 GLN 304 304  ?   ?   ?   B . n 
A 1 305 CYS 305 305  ?   ?   ?   B . n 
A 1 306 GLN 306 306  ?   ?   ?   B . n 
A 1 307 PHE 307 307  ?   ?   ?   B . n 
A 1 308 GLU 308 308  ?   ?   ?   B . n 
A 1 309 ASP 309 309  ?   ?   ?   B . n 
A 1 310 LEU 310 310  ?   ?   ?   B . n 
A 1 311 ASN 311 311  ?   ?   ?   B . n 
A 1 312 LYS 312 312  ?   ?   ?   B . n 
A 1 313 ARG 313 313  ?   ?   ?   B . n 
A 1 314 LYS 314 314  ?   ?   ?   B . n 
A 1 315 ASP 315 315  ?   ?   ?   B . n 
A 1 316 THR 316 316  316 THR THR B . n 
A 1 317 LYS 317 317  317 LYS LYS B . n 
A 1 318 GLU 318 318  318 GLU GLU B . n 
A 1 319 ILE 319 319  319 ILE ILE B . n 
A 1 320 TYR 320 320  320 TYR TYR B . n 
A 1 321 THR 321 321  321 THR THR B . n 
A 1 322 HIS 322 322  322 HIS HIS B . n 
A 1 323 PHE 323 323  323 PHE PHE B . n 
A 1 324 THR 324 324  ?   ?   ?   B . n 
A 1 325 CYS 325 325  ?   ?   ?   B . n 
A 1 326 ALA 326 326  ?   ?   ?   B . n 
A 1 327 THR 327 327  ?   ?   ?   B . n 
A 1 328 ASP 328 328  ?   ?   ?   B . n 
A 1 329 THR 329 329  329 THR THR B . n 
A 1 330 LYS 330 330  330 LYS LYS B . n 
A 1 331 ASN 331 331  331 ASN ASN B . n 
A 1 332 VAL 332 332  332 VAL VAL B . n 
A 1 333 GLN 333 333  333 GLN GLN B . n 
A 1 334 PHE 334 334  334 PHE PHE B . n 
A 1 335 VAL 335 335  335 VAL VAL B . n 
A 1 336 PHE 336 336  336 PHE PHE B . n 
A 1 337 ASP 337 337  337 ASP ASP B . n 
A 1 338 ALA 338 338  338 ALA ALA B . n 
A 1 339 VAL 339 339  339 VAL VAL B . n 
A 1 340 THR 340 340  340 THR THR B . n 
A 1 341 ASP 341 341  341 ASP ASP B . n 
A 1 342 VAL 342 342  342 VAL VAL B . n 
A 1 343 ILE 343 343  343 ILE ILE B . n 
A 1 344 ILE 344 344  344 ILE ILE B . n 
A 1 345 LYS 345 345  345 LYS LYS B . n 
A 1 346 ASN 346 346  346 ASN ASN B . n 
A 1 347 ASN 347 347  347 ASN ASN B . n 
A 1 348 LEU 348 348  348 LEU LEU B . n 
A 1 349 LYS 349 349  349 LYS LYS B . n 
A 1 350 ASP 350 350  350 ASP ASP B . n 
A 1 351 CYS 351 351  351 CYS CYS B . n 
A 1 352 GLY 352 352  352 GLY GLY B . n 
A 1 353 LEU 353 353  353 LEU LEU B . n 
A 1 354 PHE 354 354  354 PHE PHE B . n 
B 2 1   GLY 1   -4   ?   ?   ?   C . n 
B 2 2   PRO 2   -3   ?   ?   ?   C . n 
B 2 3   GLY 3   -2   ?   ?   ?   C . n 
B 2 4   SER 4   -1   ?   ?   ?   C . n 
B 2 5   SER 5   0    ?   ?   ?   C . n 
B 2 6   GLY 6   1    ?   ?   ?   C . n 
B 2 7   SER 7   2    ?   ?   ?   C . n 
B 2 8   GLU 8   3    ?   ?   ?   C . n 
B 2 9   LEU 9   4    ?   ?   ?   C . n 
B 2 10  ASP 10  5    ?   ?   ?   C . n 
B 2 11  GLN 11  6    ?   ?   ?   C . n 
B 2 12  LEU 12  7    ?   ?   ?   C . n 
B 2 13  ARG 13  8    ?   ?   ?   C . n 
B 2 14  GLN 14  9    ?   ?   ?   C . n 
B 2 15  GLU 15  10   ?   ?   ?   C . n 
B 2 16  ALA 16  11   ?   ?   ?   C . n 
B 2 17  GLU 17  12   ?   ?   ?   C . n 
B 2 18  GLN 18  13   ?   ?   ?   C . n 
B 2 19  LEU 19  14   ?   ?   ?   C . n 
B 2 20  LYS 20  15   ?   ?   ?   C . n 
B 2 21  ASN 21  16   ?   ?   ?   C . n 
B 2 22  GLN 22  17   ?   ?   ?   C . n 
B 2 23  ILE 23  18   ?   ?   ?   C . n 
B 2 24  ARG 24  19   ?   ?   ?   C . n 
B 2 25  ASP 25  20   ?   ?   ?   C . n 
B 2 26  ALA 26  21   ?   ?   ?   C . n 
B 2 27  ARG 27  22   ?   ?   ?   C . n 
B 2 28  LYS 28  23   ?   ?   ?   C . n 
B 2 29  ALA 29  24   ?   ?   ?   C . n 
B 2 30  CYS 30  25   ?   ?   ?   C . n 
B 2 31  ALA 31  26   ?   ?   ?   C . n 
B 2 32  ASP 32  27   ?   ?   ?   C . n 
B 2 33  ALA 33  28   ?   ?   ?   C . n 
B 2 34  THR 34  29   29  THR THR C . n 
B 2 35  LEU 35  30   30  LEU LEU C . n 
B 2 36  SER 36  31   31  SER SER C . n 
B 2 37  GLN 37  32   32  GLN GLN C . n 
B 2 38  ILE 38  33   33  ILE ILE C . n 
B 2 39  THR 39  34   34  THR THR C . n 
B 2 40  ASN 40  35   35  ASN ASN C . n 
B 2 41  ASN 41  36   36  ASN ASN C . n 
B 2 42  ILE 42  37   37  ILE ILE C . n 
B 2 43  ASP 43  38   38  ASP ASP C . n 
B 2 44  PRO 44  39   39  PRO PRO C . n 
B 2 45  VAL 45  40   40  VAL VAL C . n 
B 2 46  GLY 46  41   41  GLY GLY C . n 
B 2 47  ARG 47  42   42  ARG ARG C . n 
B 2 48  ILE 48  43   43  ILE ILE C . n 
B 2 49  GLN 49  44   44  GLN GLN C . n 
B 2 50  MET 50  45   45  MET MET C . n 
B 2 51  ARG 51  46   46  ARG ARG C . n 
B 2 52  THR 52  47   47  THR THR C . n 
B 2 53  ARG 53  48   48  ARG ARG C . n 
B 2 54  ARG 54  49   49  ARG ARG C . n 
B 2 55  THR 55  50   50  THR THR C . n 
B 2 56  LEU 56  51   51  LEU LEU C . n 
B 2 57  ARG 57  52   52  ARG ARG C . n 
B 2 58  GLY 58  53   53  GLY GLY C . n 
B 2 59  HIS 59  54   54  HIS HIS C . n 
B 2 60  LEU 60  55   55  LEU LEU C . n 
B 2 61  ALA 61  56   56  ALA ALA C . n 
B 2 62  LYS 62  57   57  LYS LYS C . n 
B 2 63  ILE 63  58   58  ILE ILE C . n 
B 2 64  TYR 64  59   59  TYR TYR C . n 
B 2 65  ALA 65  60   60  ALA ALA C . n 
B 2 66  MET 66  61   61  MET MET C . n 
B 2 67  HIS 67  62   62  HIS HIS C . n 
B 2 68  TRP 68  63   63  TRP TRP C . n 
B 2 69  GLY 69  64   64  GLY GLY C . n 
B 2 70  THR 70  65   65  THR THR C . n 
B 2 71  ASP 71  66   66  ASP ASP C . n 
B 2 72  SER 72  67   67  SER SER C . n 
B 2 73  ARG 73  68   68  ARG ARG C . n 
B 2 74  LEU 74  69   69  LEU LEU C . n 
B 2 75  LEU 75  70   70  LEU LEU C . n 
B 2 76  VAL 76  71   71  VAL VAL C . n 
B 2 77  SER 77  72   72  SER SER C . n 
B 2 78  ALA 78  73   73  ALA ALA C . n 
B 2 79  SER 79  74   74  SER SER C . n 
B 2 80  GLN 80  75   75  GLN GLN C . n 
B 2 81  ASP 81  76   76  ASP ASP C . n 
B 2 82  GLY 82  77   77  GLY GLY C . n 
B 2 83  LYS 83  78   78  LYS LYS C . n 
B 2 84  LEU 84  79   79  LEU LEU C . n 
B 2 85  ILE 85  80   80  ILE ILE C . n 
B 2 86  ILE 86  81   81  ILE ILE C . n 
B 2 87  TRP 87  82   82  TRP TRP C . n 
B 2 88  ASP 88  83   83  ASP ASP C . n 
B 2 89  SER 89  84   84  SER SER C . n 
B 2 90  TYR 90  85   85  TYR TYR C . n 
B 2 91  THR 91  86   86  THR THR C . n 
B 2 92  THR 92  87   87  THR THR C . n 
B 2 93  ASN 93  88   88  ASN ASN C . n 
B 2 94  LYS 94  89   89  LYS LYS C . n 
B 2 95  VAL 95  90   90  VAL VAL C . n 
B 2 96  HIS 96  91   91  HIS HIS C . n 
B 2 97  ALA 97  92   92  ALA ALA C . n 
B 2 98  ILE 98  93   93  ILE ILE C . n 
B 2 99  PRO 99  94   94  PRO PRO C . n 
B 2 100 LEU 100 95   95  LEU LEU C . n 
B 2 101 ARG 101 96   96  ARG ARG C . n 
B 2 102 SER 102 97   97  SER SER C . n 
B 2 103 SER 103 98   98  SER SER C . n 
B 2 104 TRP 104 99   99  TRP TRP C . n 
B 2 105 VAL 105 100  100 VAL VAL C . n 
B 2 106 MET 106 101  101 MET MET C . n 
B 2 107 THR 107 102  102 THR THR C . n 
B 2 108 CYS 108 103  103 CYS CYS C . n 
B 2 109 ALA 109 104  104 ALA ALA C . n 
B 2 110 TYR 110 105  105 TYR TYR C . n 
B 2 111 ALA 111 106  106 ALA ALA C . n 
B 2 112 PRO 112 107  107 PRO PRO C . n 
B 2 113 SER 113 108  108 SER SER C . n 
B 2 114 GLY 114 109  109 GLY GLY C . n 
B 2 115 ASN 115 110  110 ASN ASN C . n 
B 2 116 TYR 116 111  111 TYR TYR C . n 
B 2 117 VAL 117 112  112 VAL VAL C . n 
B 2 118 ALA 118 113  113 ALA ALA C . n 
B 2 119 CYS 119 114  114 CYS CYS C . n 
B 2 120 GLY 120 115  115 GLY GLY C . n 
B 2 121 GLY 121 116  116 GLY GLY C . n 
B 2 122 LEU 122 117  117 LEU LEU C . n 
B 2 123 ASP 123 118  118 ASP ASP C . n 
B 2 124 ASN 124 119  119 ASN ASN C . n 
B 2 125 ILE 125 120  120 ILE ILE C . n 
B 2 126 CYS 126 121  121 CYS CYS C . n 
B 2 127 SER 127 122  122 SER SER C . n 
B 2 128 ILE 128 123  123 ILE ILE C . n 
B 2 129 TYR 129 124  124 TYR TYR C . n 
B 2 130 ASN 130 125  125 ASN ASN C . n 
B 2 131 LEU 131 126  126 LEU LEU C . n 
B 2 132 LYS 132 127  127 LYS LYS C . n 
B 2 133 THR 133 128  128 THR THR C . n 
B 2 134 ARG 134 129  129 ARG ARG C . n 
B 2 135 GLU 135 130  130 GLU GLU C . n 
B 2 136 GLY 136 131  131 GLY GLY C . n 
B 2 137 ASN 137 132  132 ASN ASN C . n 
B 2 138 VAL 138 133  133 VAL VAL C . n 
B 2 139 ARG 139 134  134 ARG ARG C . n 
B 2 140 VAL 140 135  135 VAL VAL C . n 
B 2 141 SER 141 136  136 SER SER C . n 
B 2 142 ARG 142 137  137 ARG ARG C . n 
B 2 143 GLU 143 138  138 GLU GLU C . n 
B 2 144 LEU 144 139  139 LEU LEU C . n 
B 2 145 ALA 145 140  140 ALA ALA C . n 
B 2 146 GLY 146 141  141 GLY GLY C . n 
B 2 147 HIS 147 142  142 HIS HIS C . n 
B 2 148 THR 148 143  143 THR THR C . n 
B 2 149 GLY 149 144  144 GLY GLY C . n 
B 2 150 TYR 150 145  145 TYR TYR C . n 
B 2 151 LEU 151 146  146 LEU LEU C . n 
B 2 152 SER 152 147  147 SER SER C . n 
B 2 153 CYS 153 148  148 CYS CYS C . n 
B 2 154 CYS 154 149  149 CYS CYS C . n 
B 2 155 ARG 155 150  150 ARG ARG C . n 
B 2 156 PHE 156 151  151 PHE PHE C . n 
B 2 157 LEU 157 152  152 LEU LEU C . n 
B 2 158 ASP 158 153  153 ASP ASP C . n 
B 2 159 ASP 159 154  154 ASP ASP C . n 
B 2 160 ASN 160 155  155 ASN ASN C . n 
B 2 161 GLN 161 156  156 GLN GLN C . n 
B 2 162 ILE 162 157  157 ILE ILE C . n 
B 2 163 VAL 163 158  158 VAL VAL C . n 
B 2 164 THR 164 159  159 THR THR C . n 
B 2 165 SER 165 160  160 SER SER C . n 
B 2 166 SER 166 161  161 SER SER C . n 
B 2 167 GLY 167 162  162 GLY GLY C . n 
B 2 168 ASP 168 163  163 ASP ASP C . n 
B 2 169 THR 169 164  164 THR THR C . n 
B 2 170 THR 170 165  165 THR THR C . n 
B 2 171 CYS 171 166  166 CYS CYS C . n 
B 2 172 ALA 172 167  167 ALA ALA C . n 
B 2 173 LEU 173 168  168 LEU LEU C . n 
B 2 174 TRP 174 169  169 TRP TRP C . n 
B 2 175 ASP 175 170  170 ASP ASP C . n 
B 2 176 ILE 176 171  171 ILE ILE C . n 
B 2 177 GLU 177 172  172 GLU GLU C . n 
B 2 178 THR 178 173  173 THR THR C . n 
B 2 179 GLY 179 174  174 GLY GLY C . n 
B 2 180 GLN 180 175  175 GLN GLN C . n 
B 2 181 GLN 181 176  176 GLN GLN C . n 
B 2 182 THR 182 177  177 THR THR C . n 
B 2 183 THR 183 178  178 THR THR C . n 
B 2 184 THR 184 179  179 THR THR C . n 
B 2 185 PHE 185 180  180 PHE PHE C . n 
B 2 186 THR 186 181  181 THR THR C . n 
B 2 187 GLY 187 182  182 GLY GLY C . n 
B 2 188 HIS 188 183  183 HIS HIS C . n 
B 2 189 THR 189 184  184 THR THR C . n 
B 2 190 GLY 190 185  185 GLY GLY C . n 
B 2 191 ASP 191 186  186 ASP ASP C . n 
B 2 192 VAL 192 187  187 VAL VAL C . n 
B 2 193 MET 193 188  188 MET MET C . n 
B 2 194 SER 194 189  189 SER SER C . n 
B 2 195 LEU 195 190  190 LEU LEU C . n 
B 2 196 SER 196 191  191 SER SER C . n 
B 2 197 LEU 197 192  192 LEU LEU C . n 
B 2 198 ALA 198 193  193 ALA ALA C . n 
B 2 199 PRO 199 194  194 PRO PRO C . n 
B 2 200 ASP 200 195  195 ASP ASP C . n 
B 2 201 THR 201 196  196 THR THR C . n 
B 2 202 ARG 202 197  197 ARG ARG C . n 
B 2 203 LEU 203 198  198 LEU LEU C . n 
B 2 204 PHE 204 199  199 PHE PHE C . n 
B 2 205 VAL 205 200  200 VAL VAL C . n 
B 2 206 SER 206 201  201 SER SER C . n 
B 2 207 GLY 207 202  202 GLY GLY C . n 
B 2 208 ALA 208 203  203 ALA ALA C . n 
B 2 209 CYS 209 204  204 CYS CYS C . n 
B 2 210 ASP 210 205  205 ASP ASP C . n 
B 2 211 ALA 211 206  206 ALA ALA C . n 
B 2 212 SER 212 207  207 SER SER C . n 
B 2 213 ALA 213 208  208 ALA ALA C . n 
B 2 214 LYS 214 209  209 LYS LYS C . n 
B 2 215 LEU 215 210  210 LEU LEU C . n 
B 2 216 TRP 216 211  211 TRP TRP C . n 
B 2 217 ASP 217 212  212 ASP ASP C . n 
B 2 218 VAL 218 213  213 VAL VAL C . n 
B 2 219 ARG 219 214  214 ARG ARG C . n 
B 2 220 GLU 220 215  215 GLU GLU C . n 
B 2 221 GLY 221 216  216 GLY GLY C . n 
B 2 222 MET 222 217  217 MET MET C . n 
B 2 223 CYS 223 218  218 CYS CYS C . n 
B 2 224 ARG 224 219  219 ARG ARG C . n 
B 2 225 GLN 225 220  220 GLN GLN C . n 
B 2 226 THR 226 221  221 THR THR C . n 
B 2 227 PHE 227 222  222 PHE PHE C . n 
B 2 228 THR 228 223  223 THR THR C . n 
B 2 229 GLY 229 224  224 GLY GLY C . n 
B 2 230 HIS 230 225  225 HIS HIS C . n 
B 2 231 GLU 231 226  226 GLU GLU C . n 
B 2 232 SER 232 227  227 SER SER C . n 
B 2 233 ASP 233 228  228 ASP ASP C . n 
B 2 234 ILE 234 229  229 ILE ILE C . n 
B 2 235 ASN 235 230  230 ASN ASN C . n 
B 2 236 ALA 236 231  231 ALA ALA C . n 
B 2 237 ILE 237 232  232 ILE ILE C . n 
B 2 238 CYS 238 233  233 CYS CYS C . n 
B 2 239 PHE 239 234  234 PHE PHE C . n 
B 2 240 PHE 240 235  235 PHE PHE C . n 
B 2 241 PRO 241 236  236 PRO PRO C . n 
B 2 242 ASN 242 237  237 ASN ASN C . n 
B 2 243 GLY 243 238  238 GLY GLY C . n 
B 2 244 ASN 244 239  239 ASN ASN C . n 
B 2 245 ALA 245 240  240 ALA ALA C . n 
B 2 246 PHE 246 241  241 PHE PHE C . n 
B 2 247 ALA 247 242  242 ALA ALA C . n 
B 2 248 THR 248 243  243 THR THR C . n 
B 2 249 GLY 249 244  244 GLY GLY C . n 
B 2 250 SER 250 245  245 SER SER C . n 
B 2 251 ASP 251 246  246 ASP ASP C . n 
B 2 252 ASP 252 247  247 ASP ASP C . n 
B 2 253 ALA 253 248  248 ALA ALA C . n 
B 2 254 THR 254 249  249 THR THR C . n 
B 2 255 CYS 255 250  250 CYS CYS C . n 
B 2 256 ARG 256 251  251 ARG ARG C . n 
B 2 257 LEU 257 252  252 LEU LEU C . n 
B 2 258 PHE 258 253  253 PHE PHE C . n 
B 2 259 ASP 259 254  254 ASP ASP C . n 
B 2 260 LEU 260 255  255 LEU LEU C . n 
B 2 261 ARG 261 256  256 ARG ARG C . n 
B 2 262 ALA 262 257  257 ALA ALA C . n 
B 2 263 ASP 263 258  258 ASP ASP C . n 
B 2 264 GLN 264 259  259 GLN GLN C . n 
B 2 265 GLU 265 260  260 GLU GLU C . n 
B 2 266 LEU 266 261  261 LEU LEU C . n 
B 2 267 MET 267 262  262 MET MET C . n 
B 2 268 THR 268 263  263 THR THR C . n 
B 2 269 TYR 269 264  264 TYR TYR C . n 
B 2 270 SER 270 265  265 SER SER C . n 
B 2 271 HIS 271 266  266 HIS HIS C . n 
B 2 272 ASP 272 267  267 ASP ASP C . n 
B 2 273 ASN 273 268  268 ASN ASN C . n 
B 2 274 ILE 274 269  269 ILE ILE C . n 
B 2 275 ILE 275 270  270 ILE ILE C . n 
B 2 276 CYS 276 271  271 CYS CYS C . n 
B 2 277 GLY 277 272  272 GLY GLY C . n 
B 2 278 ILE 278 273  273 ILE ILE C . n 
B 2 279 THR 279 274  274 THR THR C . n 
B 2 280 SER 280 275  275 SER SER C . n 
B 2 281 VAL 281 276  276 VAL VAL C . n 
B 2 282 SER 282 277  277 SER SER C . n 
B 2 283 PHE 283 278  278 PHE PHE C . n 
B 2 284 SER 284 279  279 SER SER C . n 
B 2 285 LYS 285 280  280 LYS LYS C . n 
B 2 286 SER 286 281  281 SER SER C . n 
B 2 287 GLY 287 282  282 GLY GLY C . n 
B 2 288 ARG 288 283  283 ARG ARG C . n 
B 2 289 LEU 289 284  284 LEU LEU C . n 
B 2 290 LEU 290 285  285 LEU LEU C . n 
B 2 291 LEU 291 286  286 LEU LEU C . n 
B 2 292 ALA 292 287  287 ALA ALA C . n 
B 2 293 GLY 293 288  288 GLY GLY C . n 
B 2 294 TYR 294 289  289 TYR TYR C . n 
B 2 295 ASP 295 290  290 ASP ASP C . n 
B 2 296 ASP 296 291  291 ASP ASP C . n 
B 2 297 PHE 297 292  292 PHE PHE C . n 
B 2 298 ASN 298 293  293 ASN ASN C . n 
B 2 299 CYS 299 294  294 CYS CYS C . n 
B 2 300 ASN 300 295  295 ASN ASN C . n 
B 2 301 VAL 301 296  296 VAL VAL C . n 
B 2 302 TRP 302 297  297 TRP TRP C . n 
B 2 303 ASP 303 298  298 ASP ASP C . n 
B 2 304 ALA 304 299  299 ALA ALA C . n 
B 2 305 LEU 305 300  300 LEU LEU C . n 
B 2 306 LYS 306 301  301 LYS LYS C . n 
B 2 307 ALA 307 302  302 ALA ALA C . n 
B 2 308 ASP 308 303  303 ASP ASP C . n 
B 2 309 ARG 309 304  304 ARG ARG C . n 
B 2 310 ALA 310 305  305 ALA ALA C . n 
B 2 311 GLY 311 306  306 GLY GLY C . n 
B 2 312 VAL 312 307  307 VAL VAL C . n 
B 2 313 LEU 313 308  308 LEU LEU C . n 
B 2 314 ALA 314 309  309 ALA ALA C . n 
B 2 315 GLY 315 310  310 GLY GLY C . n 
B 2 316 HIS 316 311  311 HIS HIS C . n 
B 2 317 ASP 317 312  312 ASP ASP C . n 
B 2 318 ASN 318 313  313 ASN ASN C . n 
B 2 319 ARG 319 314  314 ARG ARG C . n 
B 2 320 VAL 320 315  315 VAL VAL C . n 
B 2 321 SER 321 316  316 SER SER C . n 
B 2 322 CYS 322 317  317 CYS CYS C . n 
B 2 323 LEU 323 318  318 LEU LEU C . n 
B 2 324 GLY 324 319  319 GLY GLY C . n 
B 2 325 VAL 325 320  320 VAL VAL C . n 
B 2 326 THR 326 321  321 THR THR C . n 
B 2 327 ASP 327 322  322 ASP ASP C . n 
B 2 328 ASP 328 323  323 ASP ASP C . n 
B 2 329 GLY 329 324  324 GLY GLY C . n 
B 2 330 MET 330 325  325 MET MET C . n 
B 2 331 ALA 331 326  326 ALA ALA C . n 
B 2 332 VAL 332 327  327 VAL VAL C . n 
B 2 333 ALA 333 328  328 ALA ALA C . n 
B 2 334 THR 334 329  329 THR THR C . n 
B 2 335 GLY 335 330  330 GLY GLY C . n 
B 2 336 SER 336 331  331 SER SER C . n 
B 2 337 TRP 337 332  332 TRP TRP C . n 
B 2 338 ASP 338 333  333 ASP ASP C . n 
B 2 339 SER 339 334  334 SER SER C . n 
B 2 340 PHE 340 335  335 PHE PHE C . n 
B 2 341 LEU 341 336  336 LEU LEU C . n 
B 2 342 LYS 342 337  337 LYS LYS C . n 
B 2 343 ILE 343 338  338 ILE ILE C . n 
B 2 344 TRP 344 339  339 TRP TRP C . n 
B 2 345 ASN 345 340  340 ASN ASN C . n 
C 3 1   MET 1   1    ?   ?   ?   E . n 
C 3 2   ALA 2   2    ?   ?   ?   E . n 
C 3 3   SER 3   3    ?   ?   ?   E . n 
C 3 4   ASN 4   4    ?   ?   ?   E . n 
C 3 5   ASN 5   5    ?   ?   ?   E . n 
C 3 6   THR 6   6    ?   ?   ?   E . n 
C 3 7   ALA 7   7    ?   ?   ?   E . n 
C 3 8   SER 8   8    ?   ?   ?   E . n 
C 3 9   ILE 9   9    ?   ?   ?   E . n 
C 3 10  ALA 10  10   ?   ?   ?   E . n 
C 3 11  GLN 11  11   ?   ?   ?   E . n 
C 3 12  ALA 12  12   ?   ?   ?   E . n 
C 3 13  ARG 13  13   ?   ?   ?   E . n 
C 3 14  LYS 14  14   ?   ?   ?   E . n 
C 3 15  LEU 15  15   ?   ?   ?   E . n 
C 3 16  VAL 16  16   ?   ?   ?   E . n 
C 3 17  GLU 17  17   ?   ?   ?   E . n 
C 3 18  GLN 18  18   ?   ?   ?   E . n 
C 3 19  LEU 19  19   ?   ?   ?   E . n 
C 3 20  LYS 20  20   ?   ?   ?   E . n 
C 3 21  MET 21  21   ?   ?   ?   E . n 
C 3 22  GLU 22  22   ?   ?   ?   E . n 
C 3 23  ALA 23  23   ?   ?   ?   E . n 
C 3 24  ASN 24  24   ?   ?   ?   E . n 
C 3 25  ILE 25  25   ?   ?   ?   E . n 
C 3 26  ASP 26  26   ?   ?   ?   E . n 
C 3 27  ARG 27  27   27  ARG ARG E . n 
C 3 28  ILE 28  28   28  ILE ILE E . n 
C 3 29  LYS 29  29   29  LYS LYS E . n 
C 3 30  VAL 30  30   30  VAL VAL E . n 
C 3 31  SER 31  31   31  SER SER E . n 
C 3 32  LYS 32  32   32  LYS LYS E . n 
C 3 33  ALA 33  33   33  ALA ALA E . n 
C 3 34  ALA 34  34   34  ALA ALA E . n 
C 3 35  ALA 35  35   35  ALA ALA E . n 
C 3 36  ASP 36  36   36  ASP ASP E . n 
C 3 37  LEU 37  37   37  LEU LEU E . n 
C 3 38  MET 38  38   38  MET MET E . n 
C 3 39  ALA 39  39   39  ALA ALA E . n 
C 3 40  TYR 40  40   40  TYR TYR E . n 
C 3 41  CYS 41  41   41  CYS CYS E . n 
C 3 42  GLU 42  42   42  GLU GLU E . n 
C 3 43  ALA 43  43   43  ALA ALA E . n 
C 3 44  HIS 44  44   44  HIS HIS E . n 
C 3 45  ALA 45  45   45  ALA ALA E . n 
C 3 46  LYS 46  46   46  LYS LYS E . n 
C 3 47  GLU 47  47   47  GLU GLU E . n 
C 3 48  ASP 48  48   48  ASP ASP E . n 
C 3 49  PRO 49  49   49  PRO PRO E . n 
C 3 50  LEU 50  50   50  LEU LEU E . n 
C 3 51  LEU 51  51   51  LEU LEU E . n 
C 3 52  THR 52  52   52  THR THR E . n 
C 3 53  PRO 53  53   53  PRO PRO E . n 
C 3 54  VAL 54  54   54  VAL VAL E . n 
C 3 55  PRO 55  55   55  PRO PRO E . n 
C 3 56  ALA 56  56   56  ALA ALA E . n 
C 3 57  SER 57  57   57  SER SER E . n 
C 3 58  GLU 58  58   58  GLU GLU E . n 
C 3 59  ASN 59  59   59  ASN ASN E . n 
C 3 60  PRO 60  60   60  PRO PRO E . n 
C 3 61  PHE 61  61   61  PHE PHE E . n 
C 3 62  ARG 62  62   62  ARG ARG E . n 
C 3 63  GLU 63  63   ?   ?   ?   E . n 
C 3 64  LYS 64  64   ?   ?   ?   E . n 
C 3 65  LYS 65  65   ?   ?   ?   E . n 
C 3 66  PHE 66  66   ?   ?   ?   E . n 
C 3 67  PHE 67  67   ?   ?   ?   E . n 
C 3 68  CYS 68  68   ?   ?   ?   E . n 
C 3 69  ALA 69  69   ?   ?   ?   E . n 
C 3 70  ILE 70  70   ?   ?   ?   E . n 
C 3 71  LEU 71  71   ?   ?   ?   E . n 
D 4 1   MET 1   1    ?   ?   ?   F . n 
D 4 2   LEU 2   2    ?   ?   ?   F . n 
D 4 3   LEU 3   3    ?   ?   ?   F . n 
D 4 4   VAL 4   4    ?   ?   ?   F . n 
D 4 5   ASN 5   5    ?   ?   ?   F . n 
D 4 6   GLN 6   6    ?   ?   ?   F . n 
D 4 7   SER 7   7    ?   ?   ?   F . n 
D 4 8   HIS 8   8    ?   ?   ?   F . n 
D 4 9   GLN 9   9    ?   ?   ?   F . n 
D 4 10  GLY 10  10   ?   ?   ?   F . n 
D 4 11  PHE 11  11   ?   ?   ?   F . n 
D 4 12  ASN 12  12   ?   ?   ?   F . n 
D 4 13  LYS 13  13   ?   ?   ?   F . n 
D 4 14  GLU 14  14   ?   ?   ?   F . n 
D 4 15  HIS 15  15   ?   ?   ?   F . n 
D 4 16  THR 16  16   ?   ?   ?   F . n 
D 4 17  SER 17  17   ?   ?   ?   F . n 
D 4 18  LYS 18  18   ?   ?   ?   F . n 
D 4 19  MET 19  19   ?   ?   ?   F . n 
D 4 20  VAL 20  20   ?   ?   ?   F . n 
D 4 21  SER 21  21   ?   ?   ?   F . n 
D 4 22  ALA 22  22   ?   ?   ?   F . n 
D 4 23  ILE 23  23   ?   ?   ?   F . n 
D 4 24  VAL 24  24   ?   ?   ?   F . n 
D 4 25  LEU 25  25   ?   ?   ?   F . n 
D 4 26  TYR 26  26   ?   ?   ?   F . n 
D 4 27  VAL 27  27   ?   ?   ?   F . n 
D 4 28  LEU 28  28   ?   ?   ?   F . n 
D 4 29  LEU 29  29   ?   ?   ?   F . n 
D 4 30  ALA 30  30   ?   ?   ?   F . n 
D 4 31  ALA 31  31   ?   ?   ?   F . n 
D 4 32  ALA 32  32   ?   ?   ?   F . n 
D 4 33  ALA 33  33   ?   ?   ?   F . n 
D 4 34  HIS 34  34   ?   ?   ?   F . n 
D 4 35  SER 35  35   ?   ?   ?   F . n 
D 4 36  ALA 36  36   ?   ?   ?   F . n 
D 4 37  PHE 37  37   ?   ?   ?   F . n 
D 4 38  ALA 38  38   ?   ?   ?   F . n 
D 4 39  ASP 39  39   ?   ?   ?   F . n 
D 4 40  VAL 40  40   40  VAL VAL F . n 
D 4 41  GLN 41  41   41  GLN GLN F . n 
D 4 42  LEU 42  42   42  LEU LEU F . n 
D 4 43  VAL 43  43   43  VAL VAL F . n 
D 4 44  GLU 44  44   44  GLU GLU F . n 
D 4 45  SER 45  45   45  SER SER F . n 
D 4 46  GLY 46  46   46  GLY GLY F . n 
D 4 47  GLY 47  47   47  GLY GLY F . n 
D 4 48  GLY 48  48   48  GLY GLY F . n 
D 4 49  LEU 49  49   49  LEU LEU F . n 
D 4 50  VAL 50  50   50  VAL VAL F . n 
D 4 51  GLN 51  51   51  GLN GLN F . n 
D 4 52  PRO 52  52   52  PRO PRO F . n 
D 4 53  GLY 53  53   53  GLY GLY F . n 
D 4 54  GLY 54  54   54  GLY GLY F . n 
D 4 55  SER 55  55   55  SER SER F . n 
D 4 56  ARG 56  56   56  ARG ARG F . n 
D 4 57  LYS 57  57   57  LYS LYS F . n 
D 4 58  LEU 58  58   58  LEU LEU F . n 
D 4 59  SER 59  59   59  SER SER F . n 
D 4 60  CYS 60  60   60  CYS CYS F . n 
D 4 61  SER 61  61   61  SER SER F . n 
D 4 62  ALA 62  62   62  ALA ALA F . n 
D 4 63  SER 63  63   63  SER SER F . n 
D 4 64  GLY 64  64   64  GLY GLY F . n 
D 4 65  PHE 65  65   65  PHE PHE F . n 
D 4 66  ALA 66  66   66  ALA ALA F . n 
D 4 67  PHE 67  67   67  PHE PHE F . n 
D 4 68  SER 68  68   68  SER SER F . n 
D 4 69  SER 69  69   69  SER SER F . n 
D 4 70  PHE 70  70   70  PHE PHE F . n 
D 4 71  GLY 71  71   71  GLY GLY F . n 
D 4 72  MET 72  72   72  MET MET F . n 
D 4 73  HIS 73  73   73  HIS HIS F . n 
D 4 74  TRP 74  74   74  TRP TRP F . n 
D 4 75  VAL 75  75   75  VAL VAL F . n 
D 4 76  ARG 76  76   76  ARG ARG F . n 
D 4 77  GLN 77  77   77  GLN GLN F . n 
D 4 78  ALA 78  78   78  ALA ALA F . n 
D 4 79  PRO 79  79   79  PRO PRO F . n 
D 4 80  GLU 80  80   80  GLU GLU F . n 
D 4 81  LYS 81  81   81  LYS LYS F . n 
D 4 82  GLY 82  82   82  GLY GLY F . n 
D 4 83  LEU 83  83   83  LEU LEU F . n 
D 4 84  GLU 84  84   84  GLU GLU F . n 
D 4 85  TRP 85  85   85  TRP TRP F . n 
D 4 86  VAL 86  86   86  VAL VAL F . n 
D 4 87  ALA 87  87   87  ALA ALA F . n 
D 4 88  TYR 88  88   88  TYR TYR F . n 
D 4 89  ILE 89  89   89  ILE ILE F . n 
D 4 90  SER 90  90   90  SER SER F . n 
D 4 91  SER 91  91   91  SER SER F . n 
D 4 92  GLY 92  92   92  GLY GLY F . n 
D 4 93  SER 93  93   93  SER SER F . n 
D 4 94  GLY 94  94   94  GLY GLY F . n 
D 4 95  THR 95  95   95  THR THR F . n 
D 4 96  ILE 96  96   96  ILE ILE F . n 
D 4 97  TYR 97  97   97  TYR TYR F . n 
D 4 98  TYR 98  98   98  TYR TYR F . n 
D 4 99  ALA 99  99   99  ALA ALA F . n 
D 4 100 ASP 100 100  100 ASP ASP F . n 
D 4 101 THR 101 101  101 THR THR F . n 
D 4 102 VAL 102 102  102 VAL VAL F . n 
D 4 103 LYS 103 103  103 LYS LYS F . n 
D 4 104 GLY 104 104  104 GLY GLY F . n 
D 4 105 ARG 105 105  105 ARG ARG F . n 
D 4 106 PHE 106 106  106 PHE PHE F . n 
D 4 107 THR 107 107  107 THR THR F . n 
D 4 108 ILE 108 108  108 ILE ILE F . n 
D 4 109 SER 109 109  109 SER SER F . n 
D 4 110 ARG 110 110  110 ARG ARG F . n 
D 4 111 ASP 111 111  111 ASP ASP F . n 
D 4 112 ASP 112 112  112 ASP ASP F . n 
D 4 113 PRO 113 113  113 PRO PRO F . n 
D 4 114 LYS 114 114  114 LYS LYS F . n 
D 4 115 ASN 115 115  115 ASN ASN F . n 
D 4 116 THR 116 116  116 THR THR F . n 
D 4 117 LEU 117 117  117 LEU LEU F . n 
D 4 118 PHE 118 118  118 PHE PHE F . n 
D 4 119 LEU 119 119  119 LEU LEU F . n 
D 4 120 GLN 120 120  120 GLN GLN F . n 
D 4 121 MET 121 121  121 MET MET F . n 
D 4 122 THR 122 122  122 THR THR F . n 
D 4 123 SER 123 123  123 SER SER F . n 
D 4 124 LEU 124 124  124 LEU LEU F . n 
D 4 125 ARG 125 125  125 ARG ARG F . n 
D 4 126 SER 126 126  126 SER SER F . n 
D 4 127 GLU 127 127  127 GLU GLU F . n 
D 4 128 ASP 128 128  128 ASP ASP F . n 
D 4 129 THR 129 129  129 THR THR F . n 
D 4 130 ALA 130 130  130 ALA ALA F . n 
D 4 131 MET 131 131  131 MET MET F . n 
D 4 132 TYR 132 132  132 TYR TYR F . n 
D 4 133 TYR 133 133  133 TYR TYR F . n 
D 4 134 CYS 134 134  134 CYS CYS F . n 
D 4 135 VAL 135 135  135 VAL VAL F . n 
D 4 136 ARG 136 136  136 ARG ARG F . n 
D 4 137 SER 137 137  137 SER SER F . n 
D 4 138 ILE 138 138  138 ILE ILE F . n 
D 4 139 TYR 139 139  139 TYR TYR F . n 
D 4 140 TYR 140 140  140 TYR TYR F . n 
D 4 141 TYR 141 141  141 TYR TYR F . n 
D 4 142 GLY 142 142  142 GLY GLY F . n 
D 4 143 SER 143 143  143 SER SER F . n 
D 4 144 SER 144 144  144 SER SER F . n 
D 4 145 PRO 145 145  145 PRO PRO F . n 
D 4 146 PHE 146 146  146 PHE PHE F . n 
D 4 147 ASP 147 147  147 ASP ASP F . n 
D 4 148 PHE 148 148  148 PHE PHE F . n 
D 4 149 TRP 149 149  149 TRP TRP F . n 
D 4 150 GLY 150 150  150 GLY GLY F . n 
D 4 151 GLN 151 151  151 GLN GLN F . n 
D 4 152 GLY 152 152  152 GLY GLY F . n 
D 4 153 THR 153 153  153 THR THR F . n 
D 4 154 THR 154 154  154 THR THR F . n 
D 4 155 LEU 155 155  155 LEU LEU F . n 
D 4 156 THR 156 156  156 THR THR F . n 
D 4 157 VAL 157 157  157 VAL VAL F . n 
D 4 158 SER 158 158  158 SER SER F . n 
D 4 159 SER 159 159  ?   ?   ?   F . n 
D 4 160 GLY 160 160  ?   ?   ?   F . n 
D 4 161 GLY 161 161  ?   ?   ?   F . n 
D 4 162 GLY 162 162  ?   ?   ?   F . n 
D 4 163 GLY 163 163  ?   ?   ?   F . n 
D 4 164 SER 164 164  ?   ?   ?   F . n 
D 4 165 GLY 165 165  ?   ?   ?   F . n 
D 4 166 GLY 166 166  ?   ?   ?   F . n 
D 4 167 GLY 167 167  ?   ?   ?   F . n 
D 4 168 GLY 168 168  ?   ?   ?   F . n 
D 4 169 SER 169 169  ?   ?   ?   F . n 
D 4 170 GLY 170 170  ?   ?   ?   F . n 
D 4 171 GLY 171 171  ?   ?   ?   F . n 
D 4 172 GLY 172 172  ?   ?   ?   F . n 
D 4 173 GLY 173 173  ?   ?   ?   F . n 
D 4 174 SER 174 174  174 SER SER F . n 
D 4 175 ASP 175 175  175 ASP ASP F . n 
D 4 176 ILE 176 176  176 ILE ILE F . n 
D 4 177 VAL 177 177  177 VAL VAL F . n 
D 4 178 MET 178 178  178 MET MET F . n 
D 4 179 THR 179 179  179 THR THR F . n 
D 4 180 GLN 180 180  180 GLN GLN F . n 
D 4 181 ALA 181 181  181 ALA ALA F . n 
D 4 182 THR 182 182  182 THR THR F . n 
D 4 183 SER 183 183  183 SER SER F . n 
D 4 184 SER 184 184  184 SER SER F . n 
D 4 185 VAL 185 185  185 VAL VAL F . n 
D 4 186 PRO 186 186  186 PRO PRO F . n 
D 4 187 VAL 187 187  187 VAL VAL F . n 
D 4 188 THR 188 188  188 THR THR F . n 
D 4 189 PRO 189 189  189 PRO PRO F . n 
D 4 190 GLY 190 190  190 GLY GLY F . n 
D 4 191 GLU 191 191  191 GLU GLU F . n 
D 4 192 SER 192 192  192 SER SER F . n 
D 4 193 VAL 193 193  193 VAL VAL F . n 
D 4 194 SER 194 194  194 SER SER F . n 
D 4 195 ILE 195 195  195 ILE ILE F . n 
D 4 196 SER 196 196  196 SER SER F . n 
D 4 197 CYS 197 197  197 CYS CYS F . n 
D 4 198 ARG 198 198  198 ARG ARG F . n 
D 4 199 SER 199 199  199 SER SER F . n 
D 4 200 SER 200 200  200 SER SER F . n 
D 4 201 LYS 201 201  201 LYS LYS F . n 
D 4 202 SER 202 202  202 SER SER F . n 
D 4 203 LEU 203 203  203 LEU LEU F . n 
D 4 204 LEU 204 204  204 LEU LEU F . n 
D 4 205 HIS 205 205  205 HIS HIS F . n 
D 4 206 SER 206 206  206 SER SER F . n 
D 4 207 ASN 207 207  207 ASN ASN F . n 
D 4 208 GLY 208 208  208 GLY GLY F . n 
D 4 209 ASN 209 209  209 ASN ASN F . n 
D 4 210 THR 210 210  210 THR THR F . n 
D 4 211 TYR 211 211  211 TYR TYR F . n 
D 4 212 LEU 212 212  212 LEU LEU F . n 
D 4 213 TYR 213 213  213 TYR TYR F . n 
D 4 214 TRP 214 214  214 TRP TRP F . n 
D 4 215 PHE 215 215  215 PHE PHE F . n 
D 4 216 LEU 216 216  216 LEU LEU F . n 
D 4 217 GLN 217 217  217 GLN GLN F . n 
D 4 218 ARG 218 218  218 ARG ARG F . n 
D 4 219 PRO 219 219  219 PRO PRO F . n 
D 4 220 GLY 220 220  220 GLY GLY F . n 
D 4 221 GLN 221 221  221 GLN GLN F . n 
D 4 222 SER 222 222  222 SER SER F . n 
D 4 223 PRO 223 223  223 PRO PRO F . n 
D 4 224 GLN 224 224  224 GLN GLN F . n 
D 4 225 LEU 225 225  225 LEU LEU F . n 
D 4 226 LEU 226 226  226 LEU LEU F . n 
D 4 227 ILE 227 227  227 ILE ILE F . n 
D 4 228 TYR 228 228  228 TYR TYR F . n 
D 4 229 ARG 229 229  229 ARG ARG F . n 
D 4 230 MET 230 230  230 MET MET F . n 
D 4 231 SER 231 231  231 SER SER F . n 
D 4 232 ASN 232 232  232 ASN ASN F . n 
D 4 233 LEU 233 233  233 LEU LEU F . n 
D 4 234 ALA 234 234  234 ALA ALA F . n 
D 4 235 SER 235 235  235 SER SER F . n 
D 4 236 GLY 236 236  236 GLY GLY F . n 
D 4 237 VAL 237 237  237 VAL VAL F . n 
D 4 238 PRO 238 238  238 PRO PRO F . n 
D 4 239 ASP 239 239  239 ASP ASP F . n 
D 4 240 ARG 240 240  240 ARG ARG F . n 
D 4 241 PHE 241 241  241 PHE PHE F . n 
D 4 242 SER 242 242  242 SER SER F . n 
D 4 243 GLY 243 243  243 GLY GLY F . n 
D 4 244 SER 244 244  244 SER SER F . n 
D 4 245 GLY 245 245  245 GLY GLY F . n 
D 4 246 SER 246 246  246 SER SER F . n 
D 4 247 GLY 247 247  247 GLY GLY F . n 
D 4 248 THR 248 248  248 THR THR F . n 
D 4 249 ALA 249 249  249 ALA ALA F . n 
D 4 250 PHE 250 250  250 PHE PHE F . n 
D 4 251 THR 251 251  251 THR THR F . n 
D 4 252 LEU 252 252  252 LEU LEU F . n 
D 4 253 THR 253 253  253 THR THR F . n 
D 4 254 ILE 254 254  254 ILE ILE F . n 
D 4 255 SER 255 255  255 SER SER F . n 
D 4 256 ARG 256 256  256 ARG ARG F . n 
D 4 257 LEU 257 257  257 LEU LEU F . n 
D 4 258 GLU 258 258  258 GLU GLU F . n 
D 4 259 ALA 259 259  259 ALA ALA F . n 
D 4 260 GLU 260 260  260 GLU GLU F . n 
D 4 261 ASP 261 261  261 ASP ASP F . n 
D 4 262 VAL 262 262  262 VAL VAL F . n 
D 4 263 GLY 263 263  263 GLY GLY F . n 
D 4 264 VAL 264 264  264 VAL VAL F . n 
D 4 265 TYR 265 265  265 TYR TYR F . n 
D 4 266 TYR 266 266  266 TYR TYR F . n 
D 4 267 CYS 267 267  267 CYS CYS F . n 
D 4 268 MET 268 268  268 MET MET F . n 
D 4 269 GLN 269 269  269 GLN GLN F . n 
D 4 270 HIS 270 270  270 HIS HIS F . n 
D 4 271 LEU 271 271  271 LEU LEU F . n 
D 4 272 GLU 272 272  272 GLU GLU F . n 
D 4 273 TYR 273 273  273 TYR TYR F . n 
D 4 274 PRO 274 274  274 PRO PRO F . n 
D 4 275 LEU 275 275  275 LEU LEU F . n 
D 4 276 THR 276 276  276 THR THR F . n 
D 4 277 PHE 277 277  277 PHE PHE F . n 
D 4 278 GLY 278 278  278 GLY GLY F . n 
D 4 279 ALA 279 279  279 ALA ALA F . n 
D 4 280 GLY 280 280  280 GLY GLY F . n 
D 4 281 THR 281 281  281 THR THR F . n 
D 4 282 LYS 282 282  282 LYS LYS F . n 
D 4 283 LEU 283 283  283 LEU LEU F . n 
D 4 284 GLU 284 284  284 GLU GLU F . n 
D 4 285 LEU 285 285  285 LEU LEU F . n 
D 4 286 LYS 286 286  ?   ?   ?   F . n 
D 4 287 ALA 287 287  ?   ?   ?   F . n 
D 4 288 ALA 288 288  ?   ?   ?   F . n 
D 4 289 ALA 289 289  ?   ?   ?   F . n 
D 4 290 GLU 290 290  ?   ?   ?   F . n 
D 4 291 ASN 291 291  ?   ?   ?   F . n 
D 4 292 LEU 292 292  ?   ?   ?   F . n 
D 4 293 TYR 293 293  ?   ?   ?   F . n 
D 4 294 PHE 294 294  ?   ?   ?   F . n 
D 4 295 GLN 295 295  ?   ?   ?   F . n 
D 4 296 GLY 296 296  ?   ?   ?   F . n 
E 5 1   ALA 1   -105 ?   ?   ?   D . n 
E 5 2   ASP 2   -104 ?   ?   ?   D . n 
E 5 3   LEU 3   -103 ?   ?   ?   D . n 
E 5 4   GLU 4   -102 ?   ?   ?   D . n 
E 5 5   ASP 5   -101 ?   ?   ?   D . n 
E 5 6   ASN 6   -100 ?   ?   ?   D . n 
E 5 7   TRP 7   -99  ?   ?   ?   D . n 
E 5 8   GLU 8   -98  ?   ?   ?   D . n 
E 5 9   THR 9   -97  ?   ?   ?   D . n 
E 5 10  LEU 10  -96  ?   ?   ?   D . n 
E 5 11  ASN 11  -95  ?   ?   ?   D . n 
E 5 12  ASP 12  -94  ?   ?   ?   D . n 
E 5 13  ASN 13  -93  ?   ?   ?   D . n 
E 5 14  LEU 14  -92  ?   ?   ?   D . n 
E 5 15  LYS 15  -91  ?   ?   ?   D . n 
E 5 16  VAL 16  -90  ?   ?   ?   D . n 
E 5 17  ILE 17  -89  ?   ?   ?   D . n 
E 5 18  GLU 18  -88  ?   ?   ?   D . n 
E 5 19  LYS 19  -87  ?   ?   ?   D . n 
E 5 20  ALA 20  -86  ?   ?   ?   D . n 
E 5 21  ASP 21  -85  ?   ?   ?   D . n 
E 5 22  ASN 22  -84  ?   ?   ?   D . n 
E 5 23  ALA 23  -83  ?   ?   ?   D . n 
E 5 24  ALA 24  -82  ?   ?   ?   D . n 
E 5 25  GLN 25  -81  ?   ?   ?   D . n 
E 5 26  VAL 26  -80  ?   ?   ?   D . n 
E 5 27  LYS 27  -79  ?   ?   ?   D . n 
E 5 28  ASP 28  -78  ?   ?   ?   D . n 
E 5 29  ALA 29  -77  ?   ?   ?   D . n 
E 5 30  LEU 30  -76  ?   ?   ?   D . n 
E 5 31  THR 31  -75  ?   ?   ?   D . n 
E 5 32  LYS 32  -74  ?   ?   ?   D . n 
E 5 33  MET 33  -73  ?   ?   ?   D . n 
E 5 34  ARG 34  -72  ?   ?   ?   D . n 
E 5 35  ALA 35  -71  ?   ?   ?   D . n 
E 5 36  ALA 36  -70  ?   ?   ?   D . n 
E 5 37  ALA 37  -69  ?   ?   ?   D . n 
E 5 38  LEU 38  -68  ?   ?   ?   D . n 
E 5 39  ASP 39  -67  ?   ?   ?   D . n 
E 5 40  ALA 40  -66  ?   ?   ?   D . n 
E 5 41  GLN 41  -65  ?   ?   ?   D . n 
E 5 42  LYS 42  -64  ?   ?   ?   D . n 
E 5 43  ALA 43  -63  ?   ?   ?   D . n 
E 5 44  THR 44  -62  ?   ?   ?   D . n 
E 5 45  PRO 45  -61  ?   ?   ?   D . n 
E 5 46  PRO 46  -60  ?   ?   ?   D . n 
E 5 47  LYS 47  -59  ?   ?   ?   D . n 
E 5 48  LEU 48  -58  ?   ?   ?   D . n 
E 5 49  GLU 49  -57  ?   ?   ?   D . n 
E 5 50  ASP 50  -56  ?   ?   ?   D . n 
E 5 51  LYS 51  -55  ?   ?   ?   D . n 
E 5 52  SER 52  -54  ?   ?   ?   D . n 
E 5 53  PRO 53  -53  ?   ?   ?   D . n 
E 5 54  ASP 54  -52  ?   ?   ?   D . n 
E 5 55  SER 55  -51  ?   ?   ?   D . n 
E 5 56  PRO 56  -50  ?   ?   ?   D . n 
E 5 57  GLU 57  -49  ?   ?   ?   D . n 
E 5 58  MET 58  -48  ?   ?   ?   D . n 
E 5 59  LYS 59  -47  ?   ?   ?   D . n 
E 5 60  ASP 60  -46  ?   ?   ?   D . n 
E 5 61  PHE 61  -45  ?   ?   ?   D . n 
E 5 62  ARG 62  -44  ?   ?   ?   D . n 
E 5 63  HIS 63  -43  ?   ?   ?   D . n 
E 5 64  GLY 64  -42  ?   ?   ?   D . n 
E 5 65  PHE 65  -41  ?   ?   ?   D . n 
E 5 66  ASP 66  -40  ?   ?   ?   D . n 
E 5 67  ILE 67  -39  ?   ?   ?   D . n 
E 5 68  LEU 68  -38  ?   ?   ?   D . n 
E 5 69  VAL 69  -37  ?   ?   ?   D . n 
E 5 70  GLY 70  -36  ?   ?   ?   D . n 
E 5 71  GLN 71  -35  ?   ?   ?   D . n 
E 5 72  ILE 72  -34  ?   ?   ?   D . n 
E 5 73  ASP 73  -33  ?   ?   ?   D . n 
E 5 74  ASP 74  -32  ?   ?   ?   D . n 
E 5 75  ALA 75  -31  ?   ?   ?   D . n 
E 5 76  LEU 76  -30  ?   ?   ?   D . n 
E 5 77  LYS 77  -29  ?   ?   ?   D . n 
E 5 78  LEU 78  -28  ?   ?   ?   D . n 
E 5 79  ALA 79  -27  ?   ?   ?   D . n 
E 5 80  ASN 80  -26  ?   ?   ?   D . n 
E 5 81  GLU 81  -25  ?   ?   ?   D . n 
E 5 82  GLY 82  -24  ?   ?   ?   D . n 
E 5 83  LYS 83  -23  ?   ?   ?   D . n 
E 5 84  VAL 84  -22  ?   ?   ?   D . n 
E 5 85  LYS 85  -21  ?   ?   ?   D . n 
E 5 86  GLU 86  -20  ?   ?   ?   D . n 
E 5 87  ALA 87  -19  ?   ?   ?   D . n 
E 5 88  GLN 88  -18  ?   ?   ?   D . n 
E 5 89  ALA 89  -17  ?   ?   ?   D . n 
E 5 90  ALA 90  -16  ?   ?   ?   D . n 
E 5 91  ALA 91  -15  ?   ?   ?   D . n 
E 5 92  GLU 92  -14  ?   ?   ?   D . n 
E 5 93  GLN 93  -13  ?   ?   ?   D . n 
E 5 94  LEU 94  -12  ?   ?   ?   D . n 
E 5 95  LYS 95  -11  ?   ?   ?   D . n 
E 5 96  THR 96  -10  ?   ?   ?   D . n 
E 5 97  THR 97  -9   ?   ?   ?   D . n 
E 5 98  ARG 98  -8   ?   ?   ?   D . n 
E 5 99  ASN 99  -7   ?   ?   ?   D . n 
E 5 100 ALA 100 -6   ?   ?   ?   D . n 
E 5 101 TYR 101 -5   ?   ?   ?   D . n 
E 5 102 ILE 102 -4   ?   ?   ?   D . n 
E 5 103 GLN 103 -3   ?   ?   ?   D . n 
E 5 104 LYS 104 -2   ?   ?   ?   D . n 
E 5 105 TYR 105 -1   ?   ?   ?   D . n 
E 5 106 LEU 106 0    ?   ?   ?   D . n 
E 5 107 MET 107 1    ?   ?   ?   D . n 
E 5 108 ASP 108 2    ?   ?   ?   D . n 
E 5 109 MET 109 3    ?   ?   ?   D . n 
E 5 110 LEU 110 4    ?   ?   ?   D . n 
E 5 111 HIS 111 5    ?   ?   ?   D . n 
E 5 112 PRO 112 6    ?   ?   ?   D . n 
E 5 113 SER 113 7    ?   ?   ?   D . n 
E 5 114 SER 114 8    ?   ?   ?   D . n 
E 5 115 VAL 115 9    ?   ?   ?   D . n 
E 5 116 SER 116 10   ?   ?   ?   D . n 
E 5 117 THR 117 11   ?   ?   ?   D . n 
E 5 118 THR 118 12   ?   ?   ?   D . n 
E 5 119 SER 119 13   ?   ?   ?   D . n 
E 5 120 GLU 120 14   ?   ?   ?   D . n 
E 5 121 PRO 121 15   ?   ?   ?   D . n 
E 5 122 GLU 122 16   ?   ?   ?   D . n 
E 5 123 ASN 123 17   ?   ?   ?   D . n 
E 5 124 ALA 124 18   ?   ?   ?   D . n 
E 5 125 SER 125 19   ?   ?   ?   D . n 
E 5 126 SER 126 20   ?   ?   ?   D . n 
E 5 127 ALA 127 21   ?   ?   ?   D . n 
E 5 128 TRP 128 22   ?   ?   ?   D . n 
E 5 129 PRO 129 23   ?   ?   ?   D . n 
E 5 130 PRO 130 24   ?   ?   ?   D . n 
E 5 131 ASP 131 25   ?   ?   ?   D . n 
E 5 132 ALA 132 26   ?   ?   ?   D . n 
E 5 133 THR 133 27   ?   ?   ?   D . n 
E 5 134 LEU 134 28   ?   ?   ?   D . n 
E 5 135 GLY 135 29   ?   ?   ?   D . n 
E 5 136 ASN 136 30   ?   ?   ?   D . n 
E 5 137 VAL 137 31   ?   ?   ?   D . n 
E 5 138 SER 138 32   ?   ?   ?   D . n 
E 5 139 ALA 139 33   ?   ?   ?   D . n 
E 5 140 GLY 140 34   ?   ?   ?   D . n 
E 5 141 PRO 141 35   ?   ?   ?   D . n 
E 5 142 SER 142 36   ?   ?   ?   D . n 
E 5 143 PRO 143 37   ?   ?   ?   D . n 
E 5 144 ALA 144 38   ?   ?   ?   D . n 
E 5 145 GLY 145 39   ?   ?   ?   D . n 
E 5 146 LEU 146 40   ?   ?   ?   D . n 
E 5 147 ALA 147 41   41  ALA ALA D . n 
E 5 148 VAL 148 42   42  VAL VAL D . n 
E 5 149 SER 149 43   43  SER SER D . n 
E 5 150 GLY 150 44   44  GLY GLY D . n 
E 5 151 VAL 151 45   45  VAL VAL D . n 
E 5 152 LEU 152 46   46  LEU LEU D . n 
E 5 153 ILE 153 47   47  ILE ILE D . n 
E 5 154 PRO 154 48   48  PRO PRO D . n 
E 5 155 LEU 155 49   49  LEU LEU D . n 
E 5 156 VAL 156 50   50  VAL VAL D . n 
E 5 157 TYR 157 51   51  TYR TYR D . n 
E 5 158 LEU 158 52   52  LEU LEU D . n 
E 5 159 VAL 159 53   53  VAL VAL D . n 
E 5 160 VAL 160 54   54  VAL VAL D . n 
E 5 161 CYS 161 55   55  CYS CYS D . n 
E 5 162 VAL 162 56   56  VAL VAL D . n 
E 5 163 VAL 163 57   57  VAL VAL D . n 
E 5 164 GLY 164 58   58  GLY GLY D . n 
E 5 165 LEU 165 59   59  LEU LEU D . n 
E 5 166 LEU 166 60   60  LEU LEU D . n 
E 5 167 GLY 167 61   61  GLY GLY D . n 
E 5 168 ASN 168 62   62  ASN ASN D . n 
E 5 169 SER 169 63   63  SER SER D . n 
E 5 170 LEU 170 64   64  LEU LEU D . n 
E 5 171 VAL 171 65   65  VAL VAL D . n 
E 5 172 ILE 172 66   66  ILE ILE D . n 
E 5 173 TYR 173 67   67  TYR TYR D . n 
E 5 174 VAL 174 68   68  VAL VAL D . n 
E 5 175 VAL 175 69   69  VAL VAL D . n 
E 5 176 LEU 176 70   70  LEU LEU D . n 
E 5 177 ARG 177 71   71  ARG ARG D . n 
E 5 178 HIS 178 72   72  HIS HIS D . n 
E 5 179 THR 179 73   73  THR THR D . n 
E 5 180 ALA 180 74   74  ALA ALA D . n 
E 5 181 SER 181 75   75  SER SER D . n 
E 5 182 PRO 182 76   76  PRO PRO D . n 
E 5 183 SER 183 77   77  SER SER D . n 
E 5 184 VAL 184 78   78  VAL VAL D . n 
E 5 185 THR 185 79   79  THR THR D . n 
E 5 186 ASN 186 80   80  ASN ASN D . n 
E 5 187 VAL 187 81   81  VAL VAL D . n 
E 5 188 TYR 188 82   82  TYR TYR D . n 
E 5 189 ILE 189 83   83  ILE ILE D . n 
E 5 190 LEU 190 84   84  LEU LEU D . n 
E 5 191 ASN 191 85   85  ASN ASN D . n 
E 5 192 LEU 192 86   86  LEU LEU D . n 
E 5 193 ALA 193 87   87  ALA ALA D . n 
E 5 194 LEU 194 88   88  LEU LEU D . n 
E 5 195 ALA 195 89   89  ALA ALA D . n 
E 5 196 ASP 196 90   90  ASP ASP D . n 
E 5 197 GLU 197 91   91  GLU GLU D . n 
E 5 198 LEU 198 92   92  LEU LEU D . n 
E 5 199 PHE 199 93   93  PHE PHE D . n 
E 5 200 MET 200 94   94  MET MET D . n 
E 5 201 LEU 201 95   95  LEU LEU D . n 
E 5 202 GLY 202 96   96  GLY GLY D . n 
E 5 203 LEU 203 97   97  LEU LEU D . n 
E 5 204 PRO 204 98   98  PRO PRO D . n 
E 5 205 PHE 205 99   99  PHE PHE D . n 
E 5 206 LEU 206 100  100 LEU LEU D . n 
E 5 207 ALA 207 101  101 ALA ALA D . n 
E 5 208 ALA 208 102  102 ALA ALA D . n 
E 5 209 GLN 209 103  103 GLN GLN D . n 
E 5 210 ASN 210 104  104 ASN ASN D . n 
E 5 211 ALA 211 105  105 ALA ALA D . n 
E 5 212 LEU 212 106  106 LEU LEU D . n 
E 5 213 SER 213 107  107 SER SER D . n 
E 5 214 TYR 214 108  108 TYR TYR D . n 
E 5 215 TRP 215 109  109 TRP TRP D . n 
E 5 216 PRO 216 110  110 PRO PRO D . n 
E 5 217 PHE 217 111  111 PHE PHE D . n 
E 5 218 GLY 218 112  112 GLY GLY D . n 
E 5 219 SER 219 113  113 SER SER D . n 
E 5 220 LEU 220 114  114 LEU LEU D . n 
E 5 221 MET 221 115  115 MET MET D . n 
E 5 222 CYS 222 116  116 CYS CYS D . n 
E 5 223 ARG 223 117  117 ARG ARG D . n 
E 5 224 LEU 224 118  118 LEU LEU D . n 
E 5 225 VAL 225 119  119 VAL VAL D . n 
E 5 226 MET 226 120  120 MET MET D . n 
E 5 227 ALA 227 121  121 ALA ALA D . n 
E 5 228 VAL 228 122  122 VAL VAL D . n 
E 5 229 ASP 229 123  123 ASP ASP D . n 
E 5 230 GLY 230 124  124 GLY GLY D . n 
E 5 231 ILE 231 125  125 ILE ILE D . n 
E 5 232 ASN 232 126  126 ASN ASN D . n 
E 5 233 GLN 233 127  127 GLN GLN D . n 
E 5 234 PHE 234 128  128 PHE PHE D . n 
E 5 235 THR 235 129  129 THR THR D . n 
E 5 236 SER 236 130  130 SER SER D . n 
E 5 237 ILE 237 131  131 ILE ILE D . n 
E 5 238 PHE 238 132  132 PHE PHE D . n 
E 5 239 CYS 239 133  133 CYS CYS D . n 
E 5 240 LEU 240 134  134 LEU LEU D . n 
E 5 241 THR 241 135  135 THR THR D . n 
E 5 242 VAL 242 136  136 VAL VAL D . n 
E 5 243 MET 243 137  137 MET MET D . n 
E 5 244 SER 244 138  138 SER SER D . n 
E 5 245 VAL 245 139  139 VAL VAL D . n 
E 5 246 ASP 246 140  140 ASP ASP D . n 
E 5 247 ARG 247 141  141 ARG ARG D . n 
E 5 248 TYR 248 142  142 TYR TYR D . n 
E 5 249 LEU 249 143  143 LEU LEU D . n 
E 5 250 ALA 250 144  144 ALA ALA D . n 
E 5 251 VAL 251 145  145 VAL VAL D . n 
E 5 252 VAL 252 146  146 VAL VAL D . n 
E 5 253 HIS 253 147  147 HIS HIS D . n 
E 5 254 PRO 254 148  148 PRO PRO D . n 
E 5 255 THR 255 149  149 THR THR D . n 
E 5 256 ARG 256 150  150 ARG ARG D . n 
E 5 257 SER 257 151  151 SER SER D . n 
E 5 258 ALA 258 152  152 ALA ALA D . n 
E 5 259 ARG 259 153  153 ARG ARG D . n 
E 5 260 TRP 260 154  154 TRP TRP D . n 
E 5 261 ARG 261 155  155 ARG ARG D . n 
E 5 262 THR 262 156  156 THR THR D . n 
E 5 263 ALA 263 157  157 ALA ALA D . n 
E 5 264 PRO 264 158  158 PRO PRO D . n 
E 5 265 VAL 265 159  159 VAL VAL D . n 
E 5 266 ALA 266 160  160 ALA ALA D . n 
E 5 267 ARG 267 161  161 ARG ARG D . n 
E 5 268 THR 268 162  162 THR THR D . n 
E 5 269 VAL 269 163  163 VAL VAL D . n 
E 5 270 SER 270 164  164 SER SER D . n 
E 5 271 ALA 271 165  165 ALA ALA D . n 
E 5 272 ALA 272 166  166 ALA ALA D . n 
E 5 273 VAL 273 167  167 VAL VAL D . n 
E 5 274 TRP 274 168  168 TRP TRP D . n 
E 5 275 VAL 275 169  169 VAL VAL D . n 
E 5 276 ALA 276 170  170 ALA ALA D . n 
E 5 277 SER 277 171  171 SER SER D . n 
E 5 278 ALA 278 172  172 ALA ALA D . n 
E 5 279 VAL 279 173  173 VAL VAL D . n 
E 5 280 VAL 280 174  174 VAL VAL D . n 
E 5 281 VAL 281 175  175 VAL VAL D . n 
E 5 282 LEU 282 176  176 LEU LEU D . n 
E 5 283 PRO 283 177  177 PRO PRO D . n 
E 5 284 VAL 284 178  178 VAL VAL D . n 
E 5 285 VAL 285 179  179 VAL VAL D . n 
E 5 286 VAL 286 180  180 VAL VAL D . n 
E 5 287 PHE 287 181  181 PHE PHE D . n 
E 5 288 SER 288 182  182 SER SER D . n 
E 5 289 GLY 289 183  183 GLY GLY D . n 
E 5 290 VAL 290 184  184 VAL VAL D . n 
E 5 291 PRO 291 185  185 PRO PRO D . n 
E 5 292 ARG 292 186  186 ARG ARG D . n 
E 5 293 GLY 293 187  187 GLY GLY D . n 
E 5 294 MET 294 188  188 MET MET D . n 
E 5 295 SER 295 189  189 SER SER D . n 
E 5 296 THR 296 190  190 THR THR D . n 
E 5 297 CYS 297 191  191 CYS CYS D . n 
E 5 298 HIS 298 192  192 HIS HIS D . n 
E 5 299 MET 299 193  193 MET MET D . n 
E 5 300 GLN 300 194  194 GLN GLN D . n 
E 5 301 TRP 301 195  195 TRP TRP D . n 
E 5 302 PRO 302 196  196 PRO PRO D . n 
E 5 303 GLU 303 197  197 GLU GLU D . n 
E 5 304 PRO 304 198  198 PRO PRO D . n 
E 5 305 ALA 305 199  199 ALA ALA D . n 
E 5 306 ALA 306 200  200 ALA ALA D . n 
E 5 307 ALA 307 201  201 ALA ALA D . n 
E 5 308 TRP 308 202  202 TRP TRP D . n 
E 5 309 ARG 309 203  203 ARG ARG D . n 
E 5 310 ALA 310 204  204 ALA ALA D . n 
E 5 311 GLY 311 205  205 GLY GLY D . n 
E 5 312 PHE 312 206  206 PHE PHE D . n 
E 5 313 ILE 313 207  207 ILE ILE D . n 
E 5 314 ILE 314 208  208 ILE ILE D . n 
E 5 315 TYR 315 209  209 TYR TYR D . n 
E 5 316 THR 316 210  210 THR THR D . n 
E 5 317 ALA 317 211  211 ALA ALA D . n 
E 5 318 ALA 318 212  212 ALA ALA D . n 
E 5 319 LEU 319 213  213 LEU LEU D . n 
E 5 320 GLY 320 214  214 GLY GLY D . n 
E 5 321 PHE 321 215  215 PHE PHE D . n 
E 5 322 PHE 322 216  216 PHE PHE D . n 
E 5 323 GLY 323 217  217 GLY GLY D . n 
E 5 324 PRO 324 218  218 PRO PRO D . n 
E 5 325 LEU 325 219  219 LEU LEU D . n 
E 5 326 LEU 326 220  220 LEU LEU D . n 
E 5 327 VAL 327 221  221 VAL VAL D . n 
E 5 328 ILE 328 222  222 ILE ILE D . n 
E 5 329 CYS 329 223  223 CYS CYS D . n 
E 5 330 LEU 330 224  224 LEU LEU D . n 
E 5 331 CYS 331 225  225 CYS CYS D . n 
E 5 332 TYR 332 226  226 TYR TYR D . n 
E 5 333 LEU 333 227  227 LEU LEU D . n 
E 5 334 LEU 334 228  228 LEU LEU D . n 
E 5 335 ILE 335 229  229 ILE ILE D . n 
E 5 336 VAL 336 230  230 VAL VAL D . n 
E 5 337 VAL 337 231  231 VAL VAL D . n 
E 5 338 LYS 338 232  232 LYS LYS D . n 
E 5 339 VAL 339 233  233 VAL VAL D . n 
E 5 340 ARG 340 234  234 ARG ARG D . n 
E 5 341 SER 341 235  235 SER SER D . n 
E 5 342 ALA 342 236  236 ALA ALA D . n 
E 5 343 GLY 343 237  237 GLY GLY D . n 
E 5 344 ARG 344 238  238 ARG ARG D . n 
E 5 345 ARG 345 239  239 ARG ARG D . n 
E 5 346 VAL 346 240  240 VAL VAL D . n 
E 5 347 TRP 347 241  241 TRP TRP D . n 
E 5 348 ALA 348 242  242 ALA ALA D . n 
E 5 349 PRO 349 243  ?   ?   ?   D . n 
E 5 350 SER 350 244  ?   ?   ?   D . n 
E 5 351 CYS 351 245  ?   ?   ?   D . n 
E 5 352 GLN 352 246  ?   ?   ?   D . n 
E 5 353 ARG 353 247  247 ARG ARG D . n 
E 5 354 ARG 354 248  248 ARG ARG D . n 
E 5 355 ARG 355 249  249 ARG ARG D . n 
E 5 356 ARG 356 250  250 ARG ARG D . n 
E 5 357 SER 357 251  251 SER SER D . n 
E 5 358 GLU 358 252  252 GLU GLU D . n 
E 5 359 ARG 359 253  253 ARG ARG D . n 
E 5 360 ARG 360 254  254 ARG ARG D . n 
E 5 361 VAL 361 255  255 VAL VAL D . n 
E 5 362 THR 362 256  256 THR THR D . n 
E 5 363 ARG 363 257  257 ARG ARG D . n 
E 5 364 MET 364 258  258 MET MET D . n 
E 5 365 VAL 365 259  259 VAL VAL D . n 
E 5 366 VAL 366 260  260 VAL VAL D . n 
E 5 367 ALA 367 261  261 ALA ALA D . n 
E 5 368 VAL 368 262  262 VAL VAL D . n 
E 5 369 VAL 369 263  263 VAL VAL D . n 
E 5 370 ALA 370 264  264 ALA ALA D . n 
E 5 371 LEU 371 265  265 LEU LEU D . n 
E 5 372 PHE 372 266  266 PHE PHE D . n 
E 5 373 VAL 373 267  267 VAL VAL D . n 
E 5 374 LEU 374 268  268 LEU LEU D . n 
E 5 375 CYS 375 269  269 CYS CYS D . n 
E 5 376 TRP 376 270  270 TRP TRP D . n 
E 5 377 MET 377 271  271 MET MET D . n 
E 5 378 PRO 378 272  272 PRO PRO D . n 
E 5 379 PHE 379 273  273 PHE PHE D . n 
E 5 380 TYR 380 274  274 TYR TYR D . n 
E 5 381 VAL 381 275  275 VAL VAL D . n 
E 5 382 LEU 382 276  276 LEU LEU D . n 
E 5 383 ASN 383 277  277 ASN ASN D . n 
E 5 384 ILE 384 278  278 ILE ILE D . n 
E 5 385 VAL 385 279  279 VAL VAL D . n 
E 5 386 ASN 386 280  280 ASN ASN D . n 
E 5 387 VAL 387 281  281 VAL VAL D . n 
E 5 388 VAL 388 282  282 VAL VAL D . n 
E 5 389 CYS 389 283  283 CYS CYS D . n 
E 5 390 PRO 390 284  284 PRO PRO D . n 
E 5 391 LEU 391 285  285 LEU LEU D . n 
E 5 392 PRO 392 286  286 PRO PRO D . n 
E 5 393 GLU 393 287  287 GLU GLU D . n 
E 5 394 GLU 394 288  288 GLU GLU D . n 
E 5 395 PRO 395 289  289 PRO PRO D . n 
E 5 396 ALA 396 290  290 ALA ALA D . n 
E 5 397 PHE 397 291  291 PHE PHE D . n 
E 5 398 PHE 398 292  292 PHE PHE D . n 
E 5 399 GLY 399 293  293 GLY GLY D . n 
E 5 400 LEU 400 294  294 LEU LEU D . n 
E 5 401 TYR 401 295  295 TYR TYR D . n 
E 5 402 PHE 402 296  296 PHE PHE D . n 
E 5 403 LEU 403 297  297 LEU LEU D . n 
E 5 404 VAL 404 298  298 VAL VAL D . n 
E 5 405 VAL 405 299  299 VAL VAL D . n 
E 5 406 ALA 406 300  300 ALA ALA D . n 
E 5 407 LEU 407 301  301 LEU LEU D . n 
E 5 408 PRO 408 302  302 PRO PRO D . n 
E 5 409 TYR 409 303  303 TYR TYR D . n 
E 5 410 ALA 410 304  304 ALA ALA D . n 
E 5 411 ASN 411 305  305 ASN ASN D . n 
E 5 412 SER 412 306  306 SER SER D . n 
E 5 413 CYS 413 307  307 CYS CYS D . n 
E 5 414 ALA 414 308  308 ALA ALA D . n 
E 5 415 ASN 415 309  309 ASN ASN D . n 
E 5 416 PRO 416 310  310 PRO PRO D . n 
E 5 417 ILE 417 311  311 ILE ILE D . n 
E 5 418 LEU 418 312  312 LEU LEU D . n 
E 5 419 TYR 419 313  313 TYR TYR D . n 
E 5 420 GLY 420 314  314 GLY GLY D . n 
E 5 421 PHE 421 315  315 PHE PHE D . n 
E 5 422 LEU 422 316  316 LEU LEU D . n 
E 5 423 SER 423 317  317 SER SER D . n 
E 5 424 TYR 424 318  318 TYR TYR D . n 
E 5 425 ARG 425 319  319 ARG ARG D . n 
E 5 426 PHE 426 320  320 PHE PHE D . n 
E 5 427 LYS 427 321  321 LYS LYS D . n 
E 5 428 GLN 428 322  322 GLN GLN D . n 
E 5 429 GLY 429 323  323 GLY GLY D . n 
E 5 430 PHE 430 324  324 PHE PHE D . n 
E 5 431 ARG 431 325  325 ARG ARG D . n 
E 5 432 ARG 432 326  ?   ?   ?   D . n 
E 5 433 VAL 433 327  ?   ?   ?   D . n 
E 5 434 LEU 434 328  ?   ?   ?   D . n 
E 5 435 LEU 435 329  ?   ?   ?   D . n 
E 5 436 ARG 436 330  ?   ?   ?   D . n 
E 5 437 PRO 437 331  ?   ?   ?   D . n 
E 5 438 SER 438 332  ?   ?   ?   D . n 
E 5 439 ARG 439 333  ?   ?   ?   D . n 
E 5 440 ARG 440 334  ?   ?   ?   D . n 
E 5 441 VAL 441 335  ?   ?   ?   D . n 
E 5 442 ARG 442 336  ?   ?   ?   D . n 
E 5 443 SER 443 337  ?   ?   ?   D . n 
E 5 444 GLN 444 338  ?   ?   ?   D . n 
E 5 445 GLU 445 339  ?   ?   ?   D . n 
E 5 446 PRO 446 340  ?   ?   ?   D . n 
E 5 447 THR 447 341  ?   ?   ?   D . n 
E 5 448 VAL 448 342  ?   ?   ?   D . n 
E 5 449 GLY 449 343  ?   ?   ?   D . n 
E 5 450 PRO 450 344  ?   ?   ?   D . n 
E 5 451 PRO 451 345  ?   ?   ?   D . n 
E 5 452 GLU 452 346  ?   ?   ?   D . n 
E 5 453 LYS 453 347  ?   ?   ?   D . n 
E 5 454 THR 454 348  ?   ?   ?   D . n 
E 5 455 GLU 455 349  ?   ?   ?   D . n 
E 5 456 GLU 456 350  ?   ?   ?   D . n 
E 5 457 GLU 457 351  ?   ?   ?   D . n 
E 5 458 ASP 458 352  ?   ?   ?   D . n 
E 5 459 GLU 459 353  ?   ?   ?   D . n 
E 5 460 GLU 460 354  ?   ?   ?   D . n 
E 5 461 GLU 461 355  ?   ?   ?   D . n 
E 5 462 GLU 462 356  ?   ?   ?   D . n 
E 5 463 ASP 463 357  ?   ?   ?   D . n 
E 5 464 GLY 464 358  ?   ?   ?   D . n 
E 5 465 GLU 465 359  ?   ?   ?   D . n 
E 5 466 GLU 466 360  ?   ?   ?   D . n 
E 5 467 SER 467 361  ?   ?   ?   D . n 
E 5 468 ARG 468 362  ?   ?   ?   D . n 
E 5 469 GLU 469 363  ?   ?   ?   D . n 
E 5 470 GLY 470 364  ?   ?   ?   D . n 
E 5 471 GLY 471 365  ?   ?   ?   D . n 
E 5 472 LYS 472 366  ?   ?   ?   D . n 
E 5 473 GLY 473 367  ?   ?   ?   D . n 
E 5 474 LYS 474 368  ?   ?   ?   D . n 
E 5 475 GLU 475 369  ?   ?   ?   D . n 
E 5 476 MET 476 370  ?   ?   ?   D . n 
E 5 477 ASN 477 371  ?   ?   ?   D . n 
E 5 478 GLY 478 372  ?   ?   ?   D . n 
E 5 479 ARG 479 373  ?   ?   ?   D . n 
E 5 480 VAL 480 374  ?   ?   ?   D . n 
E 5 481 SER 481 375  ?   ?   ?   D . n 
E 5 482 GLN 482 376  ?   ?   ?   D . n 
E 5 483 ILE 483 377  ?   ?   ?   D . n 
E 5 484 THR 484 378  ?   ?   ?   D . n 
E 5 485 GLN 485 379  ?   ?   ?   D . n 
E 5 486 PRO 486 380  ?   ?   ?   D . n 
E 5 487 GLY 487 381  ?   ?   ?   D . n 
E 5 488 THR 488 382  ?   ?   ?   D . n 
E 5 489 SER 489 383  ?   ?   ?   D . n 
E 5 490 GLY 490 384  ?   ?   ?   D . n 
E 5 491 GLN 491 385  ?   ?   ?   D . n 
E 5 492 GLU 492 386  ?   ?   ?   D . n 
E 5 493 ARG 493 387  ?   ?   ?   D . n 
E 5 494 PRO 494 388  ?   ?   ?   D . n 
E 5 495 PRO 495 389  ?   ?   ?   D . n 
E 5 496 SER 496 390  ?   ?   ?   D . n 
E 5 497 ARG 497 391  ?   ?   ?   D . n 
E 5 498 VAL 498 392  ?   ?   ?   D . n 
E 5 499 ALA 499 393  ?   ?   ?   D . n 
E 5 500 SER 500 394  ?   ?   ?   D . n 
E 5 501 LYS 501 395  ?   ?   ?   D . n 
E 5 502 GLU 502 396  ?   ?   ?   D . n 
E 5 503 GLN 503 397  ?   ?   ?   D . n 
E 5 504 GLN 504 398  ?   ?   ?   D . n 
E 5 505 LEU 505 399  ?   ?   ?   D . n 
E 5 506 LEU 506 400  ?   ?   ?   D . n 
E 5 507 PRO 507 401  ?   ?   ?   D . n 
E 5 508 GLN 508 402  ?   ?   ?   D . n 
E 5 509 GLU 509 403  ?   ?   ?   D . n 
E 5 510 ALA 510 404  ?   ?   ?   D . n 
E 5 511 SER 511 405  ?   ?   ?   D . n 
E 5 512 THR 512 406  ?   ?   ?   D . n 
E 5 513 GLY 513 407  ?   ?   ?   D . n 
E 5 514 GLU 514 408  ?   ?   ?   D . n 
E 5 515 LYS 515 409  ?   ?   ?   D . n 
E 5 516 SER 516 410  ?   ?   ?   D . n 
E 5 517 SER 517 411  ?   ?   ?   D . n 
E 5 518 THR 518 412  ?   ?   ?   D . n 
E 5 519 MET 519 413  ?   ?   ?   D . n 
E 5 520 ARG 520 414  ?   ?   ?   D . n 
E 5 521 ILE 521 415  ?   ?   ?   D . n 
E 5 522 SER 522 416  ?   ?   ?   D . n 
E 5 523 TYR 523 417  ?   ?   ?   D . n 
E 5 524 LEU 524 418  ?   ?   ?   D . n 
F 6 1   ALA 1   1    ?   ?   ?   S . n 
F 6 2   GLY 2   2    ?   ?   ?   S . n 
F 6 3   CYS 3   3    3   CYS CYS S . n 
F 6 4   LYS 4   4    4   LYS LYS S . n 
F 6 5   ASN 5   5    5   ASN ASN S . n 
F 6 6   PHE 6   6    6   PHE PHE S . n 
F 6 7   PHE 7   7    7   PHE PHE S . n 
F 6 8   TRP 8   8    8   TRP TRP S . n 
F 6 9   LYS 9   9    9   LYS LYS S . n 
F 6 10  THR 10  10   10  THR THR S . n 
F 6 11  PHE 11  11   11  PHE PHE S . n 
F 6 12  THR 12  12   12  THR THR S . n 
F 6 13  SER 13  13   13  SER SER S . n 
F 6 14  CYS 14  14   14  CYS CYS S . n 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1 1 Y 1 D ARG 247 ? CG  ? E ARG 353 CG  
2 1 Y 1 D ARG 247 ? CD  ? E ARG 353 CD  
3 1 Y 1 D ARG 247 ? NE  ? E ARG 353 NE  
4 1 Y 1 D ARG 247 ? CZ  ? E ARG 353 CZ  
5 1 Y 1 D ARG 247 ? NH1 ? E ARG 353 NH1 
6 1 Y 1 D ARG 247 ? NH2 ? E ARG 353 NH2 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8ZBI 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8ZBI 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8ZBI 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.entry_id                                 8ZBI 
_refine.pdbx_diffrn_id                           ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             ? 
_refine.ls_d_res_high                            . 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.B_iso_mean                               ? 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_ksol                 ? 
_refine.solvent_model_param_bsol                 ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.details                                  ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.003  ? 7831  ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.509  ? 10630 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 10.666 ? 2755  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.041  ? 1214  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.004  ? 1333  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     8ZBI 
_struct.title                        'Cryo-EM structure of Somatostatin receptor 3 (SSTR3) with Gi1 complex' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8ZBI 
_struct_keywords.text            'GPCR, ScFv16, seven transmembrane, MEMBRANE PROTEIN' 
_struct_keywords.pdbx_keywords   'MEMBRANE PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
E N N 5 ? 
F N N 6 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP GNAI1_HUMAN P63096 ? 1 
;MGCTLSAEDKAAVERSKMIDRNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEAGYSEEECKQYKAVVYSNTIQS
IIAIIRAMGRLKIDFGDSARADDARQLFVLAGAAEEGFMTAELAGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDLD
RIAQPNYIPTQQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEM
NRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICYPEYAGSNTYEEAAAYIQCQFEDLNKRKDTKEIY
THFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF
;
1   
2 UNP GBB1_HUMAN  P62873 ? 2 
;SELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLII
WDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSS
GDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAF
ATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVT
DDGMAVATGSWDSFLKIWN
;
2   
3 UNP GBG2_HUMAN  P59768 ? 3 MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFCAIL 1   
4 PDB 8ZBI        8ZBI   ? 4 ? 1   
5 UNP C562_ECOLX  P0ABE7 ? 5 
;ADLEDNMETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKATPPKLEDKSPDSPEMKDFRHGFDILVGQIDDALKLAN
EGKVKEAQAAAEQLKTTRNAYHQKY
;
23  
6 UNP SSR3_HUMAN  P32745 ? 5 
;MDMLHPSSVSTTSEPENASSAWPPDATLGNVSAGPSPAGLAVSGVLIPLVYLVVCVVGLLGNSLVIYVVLRHTASPSVTN
VYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRLVMAVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVA
RTVSAAVWVASAVVVLPVVVFSGVPRGMSTCHMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIVVKVRSAGRRV
WAPSCQRRRRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFLVVALPYANSCANPILYGFLSYRF
KQGFRRVLLRPSRRVRSQEPTVGPPEKTEEEDEEEEDGEESREGGKGKEMNGRVSQITQPGTSGQERPPSRVASKEQQLL
PQEASTGEKSSTMRISYL
;
1   
7 UNP SMS_HUMAN   P61278 ? 6 AGCKNFFWKTFTSC 103 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8ZBI B 1   ? 354 ? P63096 1   ? 354 ? 1    354 
2 2 8ZBI C 7   ? 345 ? P62873 2   ? 340 ? 2    340 
3 3 8ZBI E 1   ? 71  ? P59768 1   ? 71  ? 1    71  
4 4 8ZBI F 1   ? 296 ? 8ZBI   1   ? 296 ? 1    296 
5 5 8ZBI D 1   ? 105 ? P0ABE7 23  ? 127 ? -105 -1  
6 6 8ZBI D 107 ? 524 ? P32745 1   ? 418 ? 1    418 
7 7 8ZBI S 1   ? 14  ? P61278 103 ? 116 ? 1    14  
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
2 8ZBI GLY C 1   ? UNP P62873 ?   ?   'expression tag' -4  1 
2 8ZBI PRO C 2   ? UNP P62873 ?   ?   'expression tag' -3  2 
2 8ZBI GLY C 3   ? UNP P62873 ?   ?   'expression tag' -2  3 
2 8ZBI SER C 4   ? UNP P62873 ?   ?   'expression tag' -1  4 
2 8ZBI SER C 5   ? UNP P62873 ?   ?   'expression tag' 0   5 
2 8ZBI GLY C 6   ? UNP P62873 ?   ?   'expression tag' 1   6 
5 8ZBI TRP D 7   ? UNP P0ABE7 MET 29  conflict         -99 7 
5 8ZBI ILE D 102 ? UNP P0ABE7 HIS 124 conflict         -4  8 
5 8ZBI LEU D 106 ? UNP P0ABE7 ?   ?   linker           0   9 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   hexameric 
_pdbx_struct_assembly.oligomeric_count     6 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0 
_pdbx_struct_oper_list.matrix[1][2]         0.0 
_pdbx_struct_oper_list.matrix[1][3]         0.0 
_pdbx_struct_oper_list.vector[1]            0.0 
_pdbx_struct_oper_list.matrix[2][1]         0.0 
_pdbx_struct_oper_list.matrix[2][2]         1.0 
_pdbx_struct_oper_list.matrix[2][3]         0.0 
_pdbx_struct_oper_list.vector[2]            0.0 
_pdbx_struct_oper_list.matrix[3][1]         0.0 
_pdbx_struct_oper_list.matrix[3][2]         0.0 
_pdbx_struct_oper_list.matrix[3][3]         1.0 
_pdbx_struct_oper_list.vector[3]            0.0 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 6   ? ALA A 30  ? SER B 6   ALA B 30  1 ? 25 
HELX_P HELX_P2  AA2 GLU A 207 ? GLU A 216 ? GLU B 207 GLU B 216 1 ? 10 
HELX_P HELX_P3  AA3 LYS A 330 ? CYS A 351 ? LYS B 330 CYS B 351 1 ? 22 
HELX_P HELX_P4  AA4 LEU B 35  ? ASN B 40  ? LEU C 30  ASN C 35  1 ? 6  
HELX_P HELX_P5  AA5 LYS C 29  ? HIS C 44  ? LYS E 29  HIS E 44  1 ? 16 
HELX_P HELX_P6  AA6 ALA D 66  ? PHE D 70  ? ALA F 66  PHE F 70  5 ? 5  
HELX_P HELX_P7  AA7 ARG D 125 ? THR D 129 ? ARG F 125 THR F 129 5 ? 5  
HELX_P HELX_P8  AA8 VAL E 148 ? HIS E 178 ? VAL D 42  HIS D 72  1 ? 31 
HELX_P HELX_P9  AA9 VAL E 184 ? SER E 213 ? VAL D 78  SER D 107 1 ? 30 
HELX_P HELX_P10 AB1 SER E 219 ? HIS E 253 ? SER D 113 HIS D 147 1 ? 35 
HELX_P HELX_P11 AB2 THR E 262 ? VAL E 281 ? THR D 156 VAL D 175 1 ? 20 
HELX_P HELX_P12 AB3 VAL E 281 ? PHE E 287 ? VAL D 175 PHE D 181 1 ? 7  
HELX_P HELX_P13 AB4 PRO E 304 ? GLY E 323 ? PRO D 198 GLY D 217 1 ? 20 
HELX_P HELX_P14 AB5 GLY E 323 ? ARG E 345 ? GLY D 217 ARG D 239 1 ? 23 
HELX_P HELX_P15 AB6 ARG E 354 ? ARG E 360 ? ARG D 248 ARG D 254 1 ? 7  
HELX_P HELX_P16 AB7 THR E 362 ? CYS E 389 ? THR D 256 CYS D 283 1 ? 28 
HELX_P HELX_P17 AB8 GLU E 394 ? ALA E 396 ? GLU D 288 ALA D 290 5 ? 3  
HELX_P HELX_P18 AB9 PHE E 397 ? GLY E 420 ? PHE D 291 GLY D 314 1 ? 24 
HELX_P HELX_P19 AC1 SER E 423 ? ARG E 431 ? SER D 317 ARG D 325 1 ? 9  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ? ? D CYS 197 SG ? ? ? 1_555 D CYS 267 SG ? ? F CYS 197 F CYS 267 1_555 ? ? ? ? ? ? ? 2.033 ? ? 
disulf2 disulf ? ? E CYS 222 SG ? ? ? 1_555 E CYS 297 SG ? ? D CYS 116 D CYS 191 1_555 ? ? ? ? ? ? ? 2.034 ? ? 
disulf3 disulf ? ? F CYS 3   SG ? ? ? 1_555 F CYS 14  SG ? ? S CYS 3   S CYS 14  1_555 ? ? ? ? ? ? ? 2.030 ? ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 CYS D 197 ? CYS D 267 ? CYS F 197 ? 1_555 CYS F 267 ? 1_555 SG SG . . . None 'Disulfide bridge' 
2 CYS E 222 ? CYS E 297 ? CYS D 116 ? 1_555 CYS D 191 ? 1_555 SG SG . . . None 'Disulfide bridge' 
3 CYS F 3   ? CYS F 14  ? CYS S 3   ? 1_555 CYS S 14  ? 1_555 SG SG . . . None 'Disulfide bridge' 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 3 ? 
AA2 ? 3 ? 
AA3 ? 4 ? 
AA4 ? 4 ? 
AA5 ? 4 ? 
AA6 ? 4 ? 
AA7 ? 4 ? 
AA8 ? 3 ? 
AA9 ? 3 ? 
AB1 ? 2 ? 
AB2 ? 4 ? 
AB3 ? 6 ? 
AB4 ? 4 ? 
AB5 ? 5 ? 
AB6 ? 2 ? 
AB7 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? parallel      
AA1 2 3 ? anti-parallel 
AA2 1 2 ? parallel      
AA2 2 3 ? parallel      
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA6 3 4 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB2 1 2 ? anti-parallel 
AB2 2 3 ? anti-parallel 
AB2 3 4 ? anti-parallel 
AB3 1 2 ? parallel      
AB3 2 3 ? anti-parallel 
AB3 3 4 ? anti-parallel 
AB3 4 5 ? anti-parallel 
AB3 5 6 ? anti-parallel 
AB4 1 2 ? anti-parallel 
AB4 2 3 ? anti-parallel 
AB4 3 4 ? anti-parallel 
AB5 1 2 ? parallel      
AB5 2 3 ? anti-parallel 
AB5 3 4 ? anti-parallel 
AB5 4 5 ? anti-parallel 
AB6 1 2 ? anti-parallel 
AB7 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 GLU A 33  ? LEU A 38  ? GLU B 33  LEU B 38  
AA1 2 HIS A 195 ? ASP A 200 ? HIS B 195 ASP B 200 
AA1 3 GLU A 186 ? THR A 190 ? GLU B 186 THR B 190 
AA2 1 ILE A 221 ? PHE A 223 ? ILE B 221 PHE B 223 
AA2 2 ILE A 264 ? LEU A 266 ? ILE B 264 LEU B 266 
AA2 3 ILE A 319 ? THR A 321 ? ILE B 319 THR B 321 
AA3 1 THR B 52  ? LEU B 56  ? THR C 47  LEU C 51  
AA3 2 LEU B 341 ? TRP B 344 ? LEU C 336 TRP C 339 
AA3 3 VAL B 332 ? GLY B 335 ? VAL C 327 GLY C 330 
AA3 4 GLY B 324 ? VAL B 325 ? GLY C 319 VAL C 320 
AA4 1 ILE B 63  ? TRP B 68  ? ILE C 58  TRP C 63  
AA4 2 LEU B 74  ? SER B 79  ? LEU C 69  SER C 74  
AA4 3 LYS B 83  ? ASP B 88  ? LYS C 78  ASP C 83  
AA4 4 ASN B 93  ? PRO B 99  ? ASN C 88  PRO C 94  
AA5 1 VAL B 105 ? TYR B 110 ? VAL C 100 TYR C 105 
AA5 2 TYR B 116 ? GLY B 121 ? TYR C 111 GLY C 116 
AA5 3 CYS B 126 ? ASN B 130 ? CYS C 121 ASN C 125 
AA5 4 ARG B 139 ? LEU B 144 ? ARG C 134 LEU C 139 
AA6 1 LEU B 151 ? PHE B 156 ? LEU C 146 PHE C 151 
AA6 2 ILE B 162 ? SER B 166 ? ILE C 157 SER C 161 
AA6 3 CYS B 171 ? TRP B 174 ? CYS C 166 TRP C 169 
AA6 4 GLN B 181 ? THR B 184 ? GLN C 176 THR C 179 
AA7 1 SER B 196 ? LEU B 197 ? SER C 191 LEU C 192 
AA7 2 LEU B 203 ? GLY B 207 ? LEU C 198 GLY C 202 
AA7 3 SER B 212 ? ASP B 217 ? SER C 207 ASP C 212 
AA7 4 CYS B 223 ? THR B 228 ? CYS C 218 THR C 223 
AA8 1 ILE B 234 ? PHE B 239 ? ILE C 229 PHE C 234 
AA8 2 ALA B 245 ? SER B 250 ? ALA C 240 SER C 245 
AA8 3 CYS B 255 ? ASP B 259 ? CYS C 250 ASP C 254 
AA9 1 ILE B 278 ? PHE B 283 ? ILE C 273 PHE C 278 
AA9 2 LEU B 289 ? TYR B 294 ? LEU C 284 TYR C 289 
AA9 3 TRP B 302 ? ASP B 303 ? TRP C 297 ASP C 298 
AB1 1 CYS B 299 ? ASN B 300 ? CYS C 294 ASN C 295 
AB1 2 VAL B 312 ? LEU B 313 ? VAL C 307 LEU C 308 
AB2 1 GLN D 41  ? SER D 45  ? GLN F 41  SER F 45  
AB2 2 ARG D 56  ? SER D 63  ? ARG F 56  SER F 63  
AB2 3 THR D 116 ? MET D 121 ? THR F 116 MET F 121 
AB2 4 PHE D 106 ? ASP D 111 ? PHE F 106 ASP F 111 
AB3 1 GLY D 48  ? VAL D 50  ? GLY F 48  VAL F 50  
AB3 2 THR D 153 ? VAL D 157 ? THR F 153 VAL F 157 
AB3 3 ALA D 130 ? SER D 137 ? ALA F 130 SER F 137 
AB3 4 GLY D 71  ? GLN D 77  ? GLY F 71  GLN F 77  
AB3 5 LEU D 83  ? ILE D 89  ? LEU F 83  ILE F 89  
AB3 6 ILE D 96  ? TYR D 98  ? ILE F 96  TYR F 98  
AB4 1 MET D 178 ? THR D 179 ? MET F 178 THR F 179 
AB4 2 VAL D 193 ? SER D 199 ? VAL F 193 SER F 199 
AB4 3 PHE D 250 ? ILE D 254 ? PHE F 250 ILE F 254 
AB4 4 PHE D 241 ? SER D 244 ? PHE F 241 SER F 244 
AB5 1 VAL D 185 ? PRO D 186 ? VAL F 185 PRO F 186 
AB5 2 THR D 281 ? GLU D 284 ? THR F 281 GLU F 284 
AB5 3 VAL D 264 ? GLN D 269 ? VAL F 264 GLN F 269 
AB5 4 LEU D 212 ? GLN D 217 ? LEU F 212 GLN F 217 
AB5 5 GLN D 224 ? LEU D 225 ? GLN F 224 LEU F 225 
AB6 1 ILE D 227 ? TYR D 228 ? ILE F 227 TYR F 228 
AB6 2 ASN D 232 ? LEU D 233 ? ASN F 232 LEU F 233 
AB7 1 SER E 288 ? GLY E 289 ? SER D 182 GLY D 183 
AB7 2 HIS E 298 ? MET E 299 ? HIS D 192 MET D 193 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N LEU A 38  ? N LEU B 38  O PHE A 199 ? O PHE B 199 
AA1 2 3 O MET A 198 ? O MET B 198 N THR A 187 ? N THR B 187 
AA2 1 2 N PHE A 223 ? N PHE B 223 O ILE A 265 ? O ILE B 265 
AA2 2 3 N ILE A 264 ? N ILE B 264 O TYR A 320 ? O TYR B 320 
AA3 1 2 N LEU B 56  ? N LEU C 51  O LEU B 341 ? O LEU C 336 
AA3 2 3 O TRP B 344 ? O TRP C 339 N VAL B 332 ? N VAL C 327 
AA3 3 4 O ALA B 333 ? O ALA C 328 N GLY B 324 ? N GLY C 319 
AA4 1 2 N HIS B 67  ? N HIS C 62  O VAL B 76  ? O VAL C 71  
AA4 2 3 N LEU B 75  ? N LEU C 70  O TRP B 87  ? O TRP C 82  
AA4 3 4 N ASP B 88  ? N ASP C 83  O ASN B 93  ? O ASN C 88  
AA5 1 2 N MET B 106 ? N MET C 101 O GLY B 120 ? O GLY C 115 
AA5 2 3 N VAL B 117 ? N VAL C 112 O TYR B 129 ? O TYR C 124 
AA5 3 4 N ILE B 128 ? N ILE C 123 O SER B 141 ? O SER C 136 
AA6 1 2 N CYS B 153 ? N CYS C 148 O SER B 165 ? O SER C 160 
AA6 2 3 N THR B 164 ? N THR C 159 O ALA B 172 ? O ALA C 167 
AA6 3 4 N LEU B 173 ? N LEU C 168 O THR B 182 ? O THR C 177 
AA7 1 2 N SER B 196 ? N SER C 191 O VAL B 205 ? O VAL C 200 
AA7 2 3 N PHE B 204 ? N PHE C 199 O TRP B 216 ? O TRP C 211 
AA7 3 4 N LEU B 215 ? N LEU C 210 O GLN B 225 ? O GLN C 220 
AA8 1 2 N ALA B 236 ? N ALA C 231 O GLY B 249 ? O GLY C 244 
AA8 2 3 N PHE B 246 ? N PHE C 241 O PHE B 258 ? O PHE C 253 
AA9 1 2 N SER B 282 ? N SER C 277 O LEU B 291 ? O LEU C 286 
AA9 2 3 N LEU B 290 ? N LEU C 285 O TRP B 302 ? O TRP C 297 
AB1 1 2 N CYS B 299 ? N CYS C 294 O LEU B 313 ? O LEU C 308 
AB2 1 2 N SER D 45  ? N SER F 45  O SER D 59  ? O SER F 59  
AB2 2 3 N ARG D 56  ? N ARG F 56  O MET D 121 ? O MET F 121 
AB2 3 4 O THR D 116 ? O THR F 116 N ASP D 111 ? N ASP F 111 
AB3 1 2 N GLY D 48  ? N GLY F 48  O THR D 156 ? O THR F 156 
AB3 2 3 O THR D 153 ? O THR F 153 N TYR D 132 ? N TYR F 132 
AB3 3 4 O TYR D 133 ? O TYR F 133 N VAL D 75  ? N VAL F 75  
AB3 4 5 N TRP D 74  ? N TRP F 74  O VAL D 86  ? O VAL F 86  
AB3 5 6 N TYR D 88  ? N TYR F 88  O TYR D 97  ? O TYR F 97  
AB4 1 2 N THR D 179 ? N THR F 179 O ARG D 198 ? O ARG F 198 
AB4 2 3 N ILE D 195 ? N ILE F 195 O LEU D 252 ? O LEU F 252 
AB4 3 4 O THR D 253 ? O THR F 253 N SER D 242 ? N SER F 242 
AB5 1 2 N VAL D 185 ? N VAL F 185 O GLU D 284 ? O GLU F 284 
AB5 2 3 O THR D 281 ? O THR F 281 N TYR D 265 ? N TYR F 265 
AB5 3 4 O MET D 268 ? O MET F 268 N TYR D 213 ? N TYR F 213 
AB5 4 5 N LEU D 216 ? N LEU F 216 O GLN D 224 ? O GLN F 224 
AB6 1 2 N TYR D 228 ? N TYR F 228 O ASN D 232 ? O ASN F 232 
AB7 1 2 N GLY E 289 ? N GLY D 183 O HIS E 298 ? O HIS D 192 
# 
_pdbx_entry_details.entry_id                   8ZBI 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_ligand_of_interest     ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 OH B TYR 320 ? ? OD2 B ASP 341 ? ? 2.09 
2 1 NE C ARG 137 ? ? O   C ILE 171 ? ? 2.14 
3 1 O  B ASP 350 ? ? NH2 D ARG 319 ? ? 2.18 
4 1 O  C SER 189 ? ? OG  C SER 201 ? ? 2.18 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 THR B 219 ? ? -81.62  -71.57  
2  1 TYR C 145 ? ? -59.08  172.68  
3  1 LEU C 190 ? ? -170.19 141.22  
4  1 PRO C 236 ? ? -56.80  -6.64   
5  1 ASP C 291 ? ? -88.11  45.71   
6  1 LEU C 318 ? ? -160.56 116.00  
7  1 ALA E 45  ? ? -91.69  49.15   
8  1 PRO E 49  ? ? -78.88  46.82   
9  1 VAL F 86  ? ? -106.30 -62.09  
10 1 MET F 230 ? ? 67.98   -5.61   
11 1 SER F 246 ? ? -68.61  -179.30 
12 1 LEU F 271 ? ? -131.31 -38.29  
13 1 PRO D 110 ? ? -87.70  46.42   
14 1 PRO D 148 ? ? -68.27  -177.06 
15 1 SER D 189 ? ? 57.56   -123.53 
16 1 HIS D 192 ? ? -125.50 -167.61 
17 1 LYS S 4   ? ? 60.97   64.96   
18 1 PHE S 7   ? ? -93.74  -62.34  
19 1 LYS S 9   ? ? 57.03   19.18   
# 
_pdbx_molecule_features.prd_id    PRD_001216 
_pdbx_molecule_features.name      Somatostatin-14 
_pdbx_molecule_features.type      'Cyclic peptide' 
_pdbx_molecule_features.class     Inhibitor 
_pdbx_molecule_features.details   ? 
# 
_pdbx_molecule.instance_id   1 
_pdbx_molecule.prd_id        PRD_001216 
_pdbx_molecule.asym_id       F 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8ZBI 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         REAL 
_em_3d_fitting.ref_protocol      ? 
# 
loop_
_em_3d_fitting_list.id 
_em_3d_fitting_list.3d_fitting_id 
_em_3d_fitting_list.pdb_entry_id 
_em_3d_fitting_list.pdb_chain_id 
_em_3d_fitting_list.pdb_chain_residue_range 
_em_3d_fitting_list.details 
_em_3d_fitting_list.chain_id 
_em_3d_fitting_list.chain_residue_range 
_em_3d_fitting_list.source_name 
_em_3d_fitting_list.type 
_em_3d_fitting_list.accession_code 
_em_3d_fitting_list.initial_refinement_model_id 
1 1 7WJ5 B ? ? B ? PDB 'experimental model' 7WJ5 1 
2 1 7WJ5 C ? ? C ? PDB 'experimental model' 7WJ5 1 
3 1 7WJ5 E ? ? E ? PDB 'experimental model' 7WJ5 1 
4 1 7WJ5 F ? ? F ? PDB 'experimental model' 7WJ5 1 
# 
_em_3d_reconstruction.entry_id                    8ZBI 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   'BACK PROJECTION' 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  2.79 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               1619188 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          1 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.5 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'Cryo-EM structure of Human Somatostatin 3 receptor-Gialpha1 complex' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       '1, 2, 3, 4, 5, 6' 
# 
_em_imaging.entry_id                        8ZBI 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'TFS KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           'FEI TITAN KRIOS AUTOGRID HOLDER' 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      2.7 
_em_imaging.nominal_defocus_min             700 
_em_imaging.nominal_defocus_max             1900 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           105000 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         NITROGEN 
# 
_em_sample_support.id               1 
_em_sample_support.film_material    ? 
_em_sample_support.method           ? 
_em_sample_support.grid_material    GOLD 
_em_sample_support.grid_mesh_size   300 
_em_sample_support.grid_type        'Quantifoil R1.2/1.3' 
_em_sample_support.details          ? 
_em_sample_support.specimen_id      1 
_em_sample_support.citation_id      ? 
# 
_em_vitrification.entry_id              8ZBI 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              100 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   277 
_em_vitrification.instrument            'FEI VITROBOT MARK IV' 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                8ZBI 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
_em_single_particle_entity.entry_id              8ZBI 
_em_single_particle_entity.id                    1 
_em_single_particle_entity.image_processing_id   1 
_em_single_particle_entity.point_symmetry        C1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 B MET 1    ? A MET 1   
2   1 Y 1 B GLY 2    ? A GLY 2   
3   1 Y 1 B CYS 3    ? A CYS 3   
4   1 Y 1 B THR 4    ? A THR 4   
5   1 Y 1 B GLY 40   ? A GLY 40  
6   1 Y 1 B ALA 41   ? A ALA 41  
7   1 Y 1 B GLY 42   ? A GLY 42  
8   1 Y 1 B GLU 43   ? A GLU 43  
9   1 Y 1 B SER 44   ? A SER 44  
10  1 Y 1 B GLY 45   ? A GLY 45  
11  1 Y 1 B LYS 46   ? A LYS 46  
12  1 Y 1 B SER 47   ? A SER 47  
13  1 Y 1 B THR 48   ? A THR 48  
14  1 Y 1 B ILE 49   ? A ILE 49  
15  1 Y 1 B VAL 50   ? A VAL 50  
16  1 Y 1 B LYS 51   ? A LYS 51  
17  1 Y 1 B GLN 52   ? A GLN 52  
18  1 Y 1 B MET 53   ? A MET 53  
19  1 Y 1 B LYS 54   ? A LYS 54  
20  1 Y 1 B ILE 55   ? A ILE 55  
21  1 Y 1 B ILE 56   ? A ILE 56  
22  1 Y 1 B HIS 57   ? A HIS 57  
23  1 Y 1 B GLU 58   ? A GLU 58  
24  1 Y 1 B ALA 59   ? A ALA 59  
25  1 Y 1 B GLY 60   ? A GLY 60  
26  1 Y 1 B TYR 61   ? A TYR 61  
27  1 Y 1 B SER 62   ? A SER 62  
28  1 Y 1 B GLU 63   ? A GLU 63  
29  1 Y 1 B GLU 64   ? A GLU 64  
30  1 Y 1 B GLU 65   ? A GLU 65  
31  1 Y 1 B CYS 66   ? A CYS 66  
32  1 Y 1 B LYS 67   ? A LYS 67  
33  1 Y 1 B GLN 68   ? A GLN 68  
34  1 Y 1 B TYR 69   ? A TYR 69  
35  1 Y 1 B LYS 70   ? A LYS 70  
36  1 Y 1 B ALA 71   ? A ALA 71  
37  1 Y 1 B VAL 72   ? A VAL 72  
38  1 Y 1 B VAL 73   ? A VAL 73  
39  1 Y 1 B TYR 74   ? A TYR 74  
40  1 Y 1 B SER 75   ? A SER 75  
41  1 Y 1 B ASN 76   ? A ASN 76  
42  1 Y 1 B THR 77   ? A THR 77  
43  1 Y 1 B ILE 78   ? A ILE 78  
44  1 Y 1 B GLN 79   ? A GLN 79  
45  1 Y 1 B SER 80   ? A SER 80  
46  1 Y 1 B ILE 81   ? A ILE 81  
47  1 Y 1 B ILE 82   ? A ILE 82  
48  1 Y 1 B ALA 83   ? A ALA 83  
49  1 Y 1 B ILE 84   ? A ILE 84  
50  1 Y 1 B ILE 85   ? A ILE 85  
51  1 Y 1 B ARG 86   ? A ARG 86  
52  1 Y 1 B ALA 87   ? A ALA 87  
53  1 Y 1 B MET 88   ? A MET 88  
54  1 Y 1 B GLY 89   ? A GLY 89  
55  1 Y 1 B ARG 90   ? A ARG 90  
56  1 Y 1 B LEU 91   ? A LEU 91  
57  1 Y 1 B LYS 92   ? A LYS 92  
58  1 Y 1 B ILE 93   ? A ILE 93  
59  1 Y 1 B ASP 94   ? A ASP 94  
60  1 Y 1 B PHE 95   ? A PHE 95  
61  1 Y 1 B GLY 96   ? A GLY 96  
62  1 Y 1 B ASP 97   ? A ASP 97  
63  1 Y 1 B SER 98   ? A SER 98  
64  1 Y 1 B ALA 99   ? A ALA 99  
65  1 Y 1 B ARG 100  ? A ARG 100 
66  1 Y 1 B ALA 101  ? A ALA 101 
67  1 Y 1 B ASP 102  ? A ASP 102 
68  1 Y 1 B ASP 103  ? A ASP 103 
69  1 Y 1 B ALA 104  ? A ALA 104 
70  1 Y 1 B ARG 105  ? A ARG 105 
71  1 Y 1 B GLN 106  ? A GLN 106 
72  1 Y 1 B LEU 107  ? A LEU 107 
73  1 Y 1 B PHE 108  ? A PHE 108 
74  1 Y 1 B VAL 109  ? A VAL 109 
75  1 Y 1 B LEU 110  ? A LEU 110 
76  1 Y 1 B ALA 111  ? A ALA 111 
77  1 Y 1 B GLY 112  ? A GLY 112 
78  1 Y 1 B ALA 113  ? A ALA 113 
79  1 Y 1 B ALA 114  ? A ALA 114 
80  1 Y 1 B GLU 115  ? A GLU 115 
81  1 Y 1 B GLU 116  ? A GLU 116 
82  1 Y 1 B GLY 117  ? A GLY 117 
83  1 Y 1 B PHE 118  ? A PHE 118 
84  1 Y 1 B MET 119  ? A MET 119 
85  1 Y 1 B THR 120  ? A THR 120 
86  1 Y 1 B ALA 121  ? A ALA 121 
87  1 Y 1 B GLU 122  ? A GLU 122 
88  1 Y 1 B LEU 123  ? A LEU 123 
89  1 Y 1 B ALA 124  ? A ALA 124 
90  1 Y 1 B GLY 125  ? A GLY 125 
91  1 Y 1 B VAL 126  ? A VAL 126 
92  1 Y 1 B ILE 127  ? A ILE 127 
93  1 Y 1 B LYS 128  ? A LYS 128 
94  1 Y 1 B ARG 129  ? A ARG 129 
95  1 Y 1 B LEU 130  ? A LEU 130 
96  1 Y 1 B TRP 131  ? A TRP 131 
97  1 Y 1 B LYS 132  ? A LYS 132 
98  1 Y 1 B ASP 133  ? A ASP 133 
99  1 Y 1 B SER 134  ? A SER 134 
100 1 Y 1 B GLY 135  ? A GLY 135 
101 1 Y 1 B VAL 136  ? A VAL 136 
102 1 Y 1 B GLN 137  ? A GLN 137 
103 1 Y 1 B ALA 138  ? A ALA 138 
104 1 Y 1 B CYS 139  ? A CYS 139 
105 1 Y 1 B PHE 140  ? A PHE 140 
106 1 Y 1 B ASN 141  ? A ASN 141 
107 1 Y 1 B ARG 142  ? A ARG 142 
108 1 Y 1 B SER 143  ? A SER 143 
109 1 Y 1 B ARG 144  ? A ARG 144 
110 1 Y 1 B GLU 145  ? A GLU 145 
111 1 Y 1 B TYR 146  ? A TYR 146 
112 1 Y 1 B GLN 147  ? A GLN 147 
113 1 Y 1 B LEU 148  ? A LEU 148 
114 1 Y 1 B ASN 149  ? A ASN 149 
115 1 Y 1 B ASP 150  ? A ASP 150 
116 1 Y 1 B SER 151  ? A SER 151 
117 1 Y 1 B ALA 152  ? A ALA 152 
118 1 Y 1 B ALA 153  ? A ALA 153 
119 1 Y 1 B TYR 154  ? A TYR 154 
120 1 Y 1 B TYR 155  ? A TYR 155 
121 1 Y 1 B LEU 156  ? A LEU 156 
122 1 Y 1 B ASN 157  ? A ASN 157 
123 1 Y 1 B ASP 158  ? A ASP 158 
124 1 Y 1 B LEU 159  ? A LEU 159 
125 1 Y 1 B ASP 160  ? A ASP 160 
126 1 Y 1 B ARG 161  ? A ARG 161 
127 1 Y 1 B ILE 162  ? A ILE 162 
128 1 Y 1 B ALA 163  ? A ALA 163 
129 1 Y 1 B GLN 164  ? A GLN 164 
130 1 Y 1 B PRO 165  ? A PRO 165 
131 1 Y 1 B ASN 166  ? A ASN 166 
132 1 Y 1 B TYR 167  ? A TYR 167 
133 1 Y 1 B ILE 168  ? A ILE 168 
134 1 Y 1 B PRO 169  ? A PRO 169 
135 1 Y 1 B THR 170  ? A THR 170 
136 1 Y 1 B GLN 171  ? A GLN 171 
137 1 Y 1 B GLN 172  ? A GLN 172 
138 1 Y 1 B ASP 173  ? A ASP 173 
139 1 Y 1 B VAL 174  ? A VAL 174 
140 1 Y 1 B LEU 175  ? A LEU 175 
141 1 Y 1 B ARG 176  ? A ARG 176 
142 1 Y 1 B THR 177  ? A THR 177 
143 1 Y 1 B ARG 178  ? A ARG 178 
144 1 Y 1 B VAL 179  ? A VAL 179 
145 1 Y 1 B LYS 180  ? A LYS 180 
146 1 Y 1 B THR 181  ? A THR 181 
147 1 Y 1 B THR 182  ? A THR 182 
148 1 Y 1 B GLY 183  ? A GLY 183 
149 1 Y 1 B GLY 202  ? A GLY 202 
150 1 Y 1 B GLY 203  ? A GLY 203 
151 1 Y 1 B GLN 204  ? A GLN 204 
152 1 Y 1 B ARG 205  ? A ARG 205 
153 1 Y 1 B VAL 225  ? A VAL 225 
154 1 Y 1 B ALA 226  ? A ALA 226 
155 1 Y 1 B LEU 227  ? A LEU 227 
156 1 Y 1 B SER 228  ? A SER 228 
157 1 Y 1 B ASP 229  ? A ASP 229 
158 1 Y 1 B TYR 230  ? A TYR 230 
159 1 Y 1 B ASP 231  ? A ASP 231 
160 1 Y 1 B LEU 232  ? A LEU 232 
161 1 Y 1 B VAL 233  ? A VAL 233 
162 1 Y 1 B LEU 234  ? A LEU 234 
163 1 Y 1 B ALA 235  ? A ALA 235 
164 1 Y 1 B GLU 236  ? A GLU 236 
165 1 Y 1 B ASP 237  ? A ASP 237 
166 1 Y 1 B GLU 238  ? A GLU 238 
167 1 Y 1 B GLU 239  ? A GLU 239 
168 1 Y 1 B MET 240  ? A MET 240 
169 1 Y 1 B ASN 241  ? A ASN 241 
170 1 Y 1 B ARG 242  ? A ARG 242 
171 1 Y 1 B MET 243  ? A MET 243 
172 1 Y 1 B HIS 244  ? A HIS 244 
173 1 Y 1 B GLU 245  ? A GLU 245 
174 1 Y 1 B SER 246  ? A SER 246 
175 1 Y 1 B MET 247  ? A MET 247 
176 1 Y 1 B LYS 248  ? A LYS 248 
177 1 Y 1 B LEU 249  ? A LEU 249 
178 1 Y 1 B PHE 250  ? A PHE 250 
179 1 Y 1 B ASP 251  ? A ASP 251 
180 1 Y 1 B SER 252  ? A SER 252 
181 1 Y 1 B ILE 253  ? A ILE 253 
182 1 Y 1 B CYS 254  ? A CYS 254 
183 1 Y 1 B ASN 255  ? A ASN 255 
184 1 Y 1 B ASN 256  ? A ASN 256 
185 1 Y 1 B LYS 257  ? A LYS 257 
186 1 Y 1 B TRP 258  ? A TRP 258 
187 1 Y 1 B PHE 259  ? A PHE 259 
188 1 Y 1 B THR 260  ? A THR 260 
189 1 Y 1 B ASP 261  ? A ASP 261 
190 1 Y 1 B LEU 268  ? A LEU 268 
191 1 Y 1 B ASN 269  ? A ASN 269 
192 1 Y 1 B LYS 270  ? A LYS 270 
193 1 Y 1 B LYS 271  ? A LYS 271 
194 1 Y 1 B ASP 272  ? A ASP 272 
195 1 Y 1 B LEU 273  ? A LEU 273 
196 1 Y 1 B PHE 274  ? A PHE 274 
197 1 Y 1 B GLU 275  ? A GLU 275 
198 1 Y 1 B GLU 276  ? A GLU 276 
199 1 Y 1 B LYS 277  ? A LYS 277 
200 1 Y 1 B ILE 278  ? A ILE 278 
201 1 Y 1 B LYS 279  ? A LYS 279 
202 1 Y 1 B LYS 280  ? A LYS 280 
203 1 Y 1 B SER 281  ? A SER 281 
204 1 Y 1 B PRO 282  ? A PRO 282 
205 1 Y 1 B LEU 283  ? A LEU 283 
206 1 Y 1 B THR 284  ? A THR 284 
207 1 Y 1 B ILE 285  ? A ILE 285 
208 1 Y 1 B CYS 286  ? A CYS 286 
209 1 Y 1 B TYR 287  ? A TYR 287 
210 1 Y 1 B PRO 288  ? A PRO 288 
211 1 Y 1 B GLU 289  ? A GLU 289 
212 1 Y 1 B TYR 290  ? A TYR 290 
213 1 Y 1 B ALA 291  ? A ALA 291 
214 1 Y 1 B GLY 292  ? A GLY 292 
215 1 Y 1 B SER 293  ? A SER 293 
216 1 Y 1 B ASN 294  ? A ASN 294 
217 1 Y 1 B THR 295  ? A THR 295 
218 1 Y 1 B TYR 296  ? A TYR 296 
219 1 Y 1 B GLU 297  ? A GLU 297 
220 1 Y 1 B GLU 298  ? A GLU 298 
221 1 Y 1 B ALA 299  ? A ALA 299 
222 1 Y 1 B ALA 300  ? A ALA 300 
223 1 Y 1 B ALA 301  ? A ALA 301 
224 1 Y 1 B TYR 302  ? A TYR 302 
225 1 Y 1 B ILE 303  ? A ILE 303 
226 1 Y 1 B GLN 304  ? A GLN 304 
227 1 Y 1 B CYS 305  ? A CYS 305 
228 1 Y 1 B GLN 306  ? A GLN 306 
229 1 Y 1 B PHE 307  ? A PHE 307 
230 1 Y 1 B GLU 308  ? A GLU 308 
231 1 Y 1 B ASP 309  ? A ASP 309 
232 1 Y 1 B LEU 310  ? A LEU 310 
233 1 Y 1 B ASN 311  ? A ASN 311 
234 1 Y 1 B LYS 312  ? A LYS 312 
235 1 Y 1 B ARG 313  ? A ARG 313 
236 1 Y 1 B LYS 314  ? A LYS 314 
237 1 Y 1 B ASP 315  ? A ASP 315 
238 1 Y 1 B THR 324  ? A THR 324 
239 1 Y 1 B CYS 325  ? A CYS 325 
240 1 Y 1 B ALA 326  ? A ALA 326 
241 1 Y 1 B THR 327  ? A THR 327 
242 1 Y 1 B ASP 328  ? A ASP 328 
243 1 Y 1 C GLY -4   ? B GLY 1   
244 1 Y 1 C PRO -3   ? B PRO 2   
245 1 Y 1 C GLY -2   ? B GLY 3   
246 1 Y 1 C SER -1   ? B SER 4   
247 1 Y 1 C SER 0    ? B SER 5   
248 1 Y 1 C GLY 1    ? B GLY 6   
249 1 Y 1 C SER 2    ? B SER 7   
250 1 Y 1 C GLU 3    ? B GLU 8   
251 1 Y 1 C LEU 4    ? B LEU 9   
252 1 Y 1 C ASP 5    ? B ASP 10  
253 1 Y 1 C GLN 6    ? B GLN 11  
254 1 Y 1 C LEU 7    ? B LEU 12  
255 1 Y 1 C ARG 8    ? B ARG 13  
256 1 Y 1 C GLN 9    ? B GLN 14  
257 1 Y 1 C GLU 10   ? B GLU 15  
258 1 Y 1 C ALA 11   ? B ALA 16  
259 1 Y 1 C GLU 12   ? B GLU 17  
260 1 Y 1 C GLN 13   ? B GLN 18  
261 1 Y 1 C LEU 14   ? B LEU 19  
262 1 Y 1 C LYS 15   ? B LYS 20  
263 1 Y 1 C ASN 16   ? B ASN 21  
264 1 Y 1 C GLN 17   ? B GLN 22  
265 1 Y 1 C ILE 18   ? B ILE 23  
266 1 Y 1 C ARG 19   ? B ARG 24  
267 1 Y 1 C ASP 20   ? B ASP 25  
268 1 Y 1 C ALA 21   ? B ALA 26  
269 1 Y 1 C ARG 22   ? B ARG 27  
270 1 Y 1 C LYS 23   ? B LYS 28  
271 1 Y 1 C ALA 24   ? B ALA 29  
272 1 Y 1 C CYS 25   ? B CYS 30  
273 1 Y 1 C ALA 26   ? B ALA 31  
274 1 Y 1 C ASP 27   ? B ASP 32  
275 1 Y 1 C ALA 28   ? B ALA 33  
276 1 Y 1 E MET 1    ? C MET 1   
277 1 Y 1 E ALA 2    ? C ALA 2   
278 1 Y 1 E SER 3    ? C SER 3   
279 1 Y 1 E ASN 4    ? C ASN 4   
280 1 Y 1 E ASN 5    ? C ASN 5   
281 1 Y 1 E THR 6    ? C THR 6   
282 1 Y 1 E ALA 7    ? C ALA 7   
283 1 Y 1 E SER 8    ? C SER 8   
284 1 Y 1 E ILE 9    ? C ILE 9   
285 1 Y 1 E ALA 10   ? C ALA 10  
286 1 Y 1 E GLN 11   ? C GLN 11  
287 1 Y 1 E ALA 12   ? C ALA 12  
288 1 Y 1 E ARG 13   ? C ARG 13  
289 1 Y 1 E LYS 14   ? C LYS 14  
290 1 Y 1 E LEU 15   ? C LEU 15  
291 1 Y 1 E VAL 16   ? C VAL 16  
292 1 Y 1 E GLU 17   ? C GLU 17  
293 1 Y 1 E GLN 18   ? C GLN 18  
294 1 Y 1 E LEU 19   ? C LEU 19  
295 1 Y 1 E LYS 20   ? C LYS 20  
296 1 Y 1 E MET 21   ? C MET 21  
297 1 Y 1 E GLU 22   ? C GLU 22  
298 1 Y 1 E ALA 23   ? C ALA 23  
299 1 Y 1 E ASN 24   ? C ASN 24  
300 1 Y 1 E ILE 25   ? C ILE 25  
301 1 Y 1 E ASP 26   ? C ASP 26  
302 1 Y 1 E GLU 63   ? C GLU 63  
303 1 Y 1 E LYS 64   ? C LYS 64  
304 1 Y 1 E LYS 65   ? C LYS 65  
305 1 Y 1 E PHE 66   ? C PHE 66  
306 1 Y 1 E PHE 67   ? C PHE 67  
307 1 Y 1 E CYS 68   ? C CYS 68  
308 1 Y 1 E ALA 69   ? C ALA 69  
309 1 Y 1 E ILE 70   ? C ILE 70  
310 1 Y 1 E LEU 71   ? C LEU 71  
311 1 Y 1 F MET 1    ? D MET 1   
312 1 Y 1 F LEU 2    ? D LEU 2   
313 1 Y 1 F LEU 3    ? D LEU 3   
314 1 Y 1 F VAL 4    ? D VAL 4   
315 1 Y 1 F ASN 5    ? D ASN 5   
316 1 Y 1 F GLN 6    ? D GLN 6   
317 1 Y 1 F SER 7    ? D SER 7   
318 1 Y 1 F HIS 8    ? D HIS 8   
319 1 Y 1 F GLN 9    ? D GLN 9   
320 1 Y 1 F GLY 10   ? D GLY 10  
321 1 Y 1 F PHE 11   ? D PHE 11  
322 1 Y 1 F ASN 12   ? D ASN 12  
323 1 Y 1 F LYS 13   ? D LYS 13  
324 1 Y 1 F GLU 14   ? D GLU 14  
325 1 Y 1 F HIS 15   ? D HIS 15  
326 1 Y 1 F THR 16   ? D THR 16  
327 1 Y 1 F SER 17   ? D SER 17  
328 1 Y 1 F LYS 18   ? D LYS 18  
329 1 Y 1 F MET 19   ? D MET 19  
330 1 Y 1 F VAL 20   ? D VAL 20  
331 1 Y 1 F SER 21   ? D SER 21  
332 1 Y 1 F ALA 22   ? D ALA 22  
333 1 Y 1 F ILE 23   ? D ILE 23  
334 1 Y 1 F VAL 24   ? D VAL 24  
335 1 Y 1 F LEU 25   ? D LEU 25  
336 1 Y 1 F TYR 26   ? D TYR 26  
337 1 Y 1 F VAL 27   ? D VAL 27  
338 1 Y 1 F LEU 28   ? D LEU 28  
339 1 Y 1 F LEU 29   ? D LEU 29  
340 1 Y 1 F ALA 30   ? D ALA 30  
341 1 Y 1 F ALA 31   ? D ALA 31  
342 1 Y 1 F ALA 32   ? D ALA 32  
343 1 Y 1 F ALA 33   ? D ALA 33  
344 1 Y 1 F HIS 34   ? D HIS 34  
345 1 Y 1 F SER 35   ? D SER 35  
346 1 Y 1 F ALA 36   ? D ALA 36  
347 1 Y 1 F PHE 37   ? D PHE 37  
348 1 Y 1 F ALA 38   ? D ALA 38  
349 1 Y 1 F ASP 39   ? D ASP 39  
350 1 Y 1 F SER 159  ? D SER 159 
351 1 Y 1 F GLY 160  ? D GLY 160 
352 1 Y 1 F GLY 161  ? D GLY 161 
353 1 Y 1 F GLY 162  ? D GLY 162 
354 1 Y 1 F GLY 163  ? D GLY 163 
355 1 Y 1 F SER 164  ? D SER 164 
356 1 Y 1 F GLY 165  ? D GLY 165 
357 1 Y 1 F GLY 166  ? D GLY 166 
358 1 Y 1 F GLY 167  ? D GLY 167 
359 1 Y 1 F GLY 168  ? D GLY 168 
360 1 Y 1 F SER 169  ? D SER 169 
361 1 Y 1 F GLY 170  ? D GLY 170 
362 1 Y 1 F GLY 171  ? D GLY 171 
363 1 Y 1 F GLY 172  ? D GLY 172 
364 1 Y 1 F GLY 173  ? D GLY 173 
365 1 Y 1 F LYS 286  ? D LYS 286 
366 1 Y 1 F ALA 287  ? D ALA 287 
367 1 Y 1 F ALA 288  ? D ALA 288 
368 1 Y 1 F ALA 289  ? D ALA 289 
369 1 Y 1 F GLU 290  ? D GLU 290 
370 1 Y 1 F ASN 291  ? D ASN 291 
371 1 Y 1 F LEU 292  ? D LEU 292 
372 1 Y 1 F TYR 293  ? D TYR 293 
373 1 Y 1 F PHE 294  ? D PHE 294 
374 1 Y 1 F GLN 295  ? D GLN 295 
375 1 Y 1 F GLY 296  ? D GLY 296 
376 1 Y 1 D ALA -105 ? E ALA 1   
377 1 Y 1 D ASP -104 ? E ASP 2   
378 1 Y 1 D LEU -103 ? E LEU 3   
379 1 Y 1 D GLU -102 ? E GLU 4   
380 1 Y 1 D ASP -101 ? E ASP 5   
381 1 Y 1 D ASN -100 ? E ASN 6   
382 1 Y 1 D TRP -99  ? E TRP 7   
383 1 Y 1 D GLU -98  ? E GLU 8   
384 1 Y 1 D THR -97  ? E THR 9   
385 1 Y 1 D LEU -96  ? E LEU 10  
386 1 Y 1 D ASN -95  ? E ASN 11  
387 1 Y 1 D ASP -94  ? E ASP 12  
388 1 Y 1 D ASN -93  ? E ASN 13  
389 1 Y 1 D LEU -92  ? E LEU 14  
390 1 Y 1 D LYS -91  ? E LYS 15  
391 1 Y 1 D VAL -90  ? E VAL 16  
392 1 Y 1 D ILE -89  ? E ILE 17  
393 1 Y 1 D GLU -88  ? E GLU 18  
394 1 Y 1 D LYS -87  ? E LYS 19  
395 1 Y 1 D ALA -86  ? E ALA 20  
396 1 Y 1 D ASP -85  ? E ASP 21  
397 1 Y 1 D ASN -84  ? E ASN 22  
398 1 Y 1 D ALA -83  ? E ALA 23  
399 1 Y 1 D ALA -82  ? E ALA 24  
400 1 Y 1 D GLN -81  ? E GLN 25  
401 1 Y 1 D VAL -80  ? E VAL 26  
402 1 Y 1 D LYS -79  ? E LYS 27  
403 1 Y 1 D ASP -78  ? E ASP 28  
404 1 Y 1 D ALA -77  ? E ALA 29  
405 1 Y 1 D LEU -76  ? E LEU 30  
406 1 Y 1 D THR -75  ? E THR 31  
407 1 Y 1 D LYS -74  ? E LYS 32  
408 1 Y 1 D MET -73  ? E MET 33  
409 1 Y 1 D ARG -72  ? E ARG 34  
410 1 Y 1 D ALA -71  ? E ALA 35  
411 1 Y 1 D ALA -70  ? E ALA 36  
412 1 Y 1 D ALA -69  ? E ALA 37  
413 1 Y 1 D LEU -68  ? E LEU 38  
414 1 Y 1 D ASP -67  ? E ASP 39  
415 1 Y 1 D ALA -66  ? E ALA 40  
416 1 Y 1 D GLN -65  ? E GLN 41  
417 1 Y 1 D LYS -64  ? E LYS 42  
418 1 Y 1 D ALA -63  ? E ALA 43  
419 1 Y 1 D THR -62  ? E THR 44  
420 1 Y 1 D PRO -61  ? E PRO 45  
421 1 Y 1 D PRO -60  ? E PRO 46  
422 1 Y 1 D LYS -59  ? E LYS 47  
423 1 Y 1 D LEU -58  ? E LEU 48  
424 1 Y 1 D GLU -57  ? E GLU 49  
425 1 Y 1 D ASP -56  ? E ASP 50  
426 1 Y 1 D LYS -55  ? E LYS 51  
427 1 Y 1 D SER -54  ? E SER 52  
428 1 Y 1 D PRO -53  ? E PRO 53  
429 1 Y 1 D ASP -52  ? E ASP 54  
430 1 Y 1 D SER -51  ? E SER 55  
431 1 Y 1 D PRO -50  ? E PRO 56  
432 1 Y 1 D GLU -49  ? E GLU 57  
433 1 Y 1 D MET -48  ? E MET 58  
434 1 Y 1 D LYS -47  ? E LYS 59  
435 1 Y 1 D ASP -46  ? E ASP 60  
436 1 Y 1 D PHE -45  ? E PHE 61  
437 1 Y 1 D ARG -44  ? E ARG 62  
438 1 Y 1 D HIS -43  ? E HIS 63  
439 1 Y 1 D GLY -42  ? E GLY 64  
440 1 Y 1 D PHE -41  ? E PHE 65  
441 1 Y 1 D ASP -40  ? E ASP 66  
442 1 Y 1 D ILE -39  ? E ILE 67  
443 1 Y 1 D LEU -38  ? E LEU 68  
444 1 Y 1 D VAL -37  ? E VAL 69  
445 1 Y 1 D GLY -36  ? E GLY 70  
446 1 Y 1 D GLN -35  ? E GLN 71  
447 1 Y 1 D ILE -34  ? E ILE 72  
448 1 Y 1 D ASP -33  ? E ASP 73  
449 1 Y 1 D ASP -32  ? E ASP 74  
450 1 Y 1 D ALA -31  ? E ALA 75  
451 1 Y 1 D LEU -30  ? E LEU 76  
452 1 Y 1 D LYS -29  ? E LYS 77  
453 1 Y 1 D LEU -28  ? E LEU 78  
454 1 Y 1 D ALA -27  ? E ALA 79  
455 1 Y 1 D ASN -26  ? E ASN 80  
456 1 Y 1 D GLU -25  ? E GLU 81  
457 1 Y 1 D GLY -24  ? E GLY 82  
458 1 Y 1 D LYS -23  ? E LYS 83  
459 1 Y 1 D VAL -22  ? E VAL 84  
460 1 Y 1 D LYS -21  ? E LYS 85  
461 1 Y 1 D GLU -20  ? E GLU 86  
462 1 Y 1 D ALA -19  ? E ALA 87  
463 1 Y 1 D GLN -18  ? E GLN 88  
464 1 Y 1 D ALA -17  ? E ALA 89  
465 1 Y 1 D ALA -16  ? E ALA 90  
466 1 Y 1 D ALA -15  ? E ALA 91  
467 1 Y 1 D GLU -14  ? E GLU 92  
468 1 Y 1 D GLN -13  ? E GLN 93  
469 1 Y 1 D LEU -12  ? E LEU 94  
470 1 Y 1 D LYS -11  ? E LYS 95  
471 1 Y 1 D THR -10  ? E THR 96  
472 1 Y 1 D THR -9   ? E THR 97  
473 1 Y 1 D ARG -8   ? E ARG 98  
474 1 Y 1 D ASN -7   ? E ASN 99  
475 1 Y 1 D ALA -6   ? E ALA 100 
476 1 Y 1 D TYR -5   ? E TYR 101 
477 1 Y 1 D ILE -4   ? E ILE 102 
478 1 Y 1 D GLN -3   ? E GLN 103 
479 1 Y 1 D LYS -2   ? E LYS 104 
480 1 Y 1 D TYR -1   ? E TYR 105 
481 1 Y 1 D LEU 0    ? E LEU 106 
482 1 Y 1 D MET 1    ? E MET 107 
483 1 Y 1 D ASP 2    ? E ASP 108 
484 1 Y 1 D MET 3    ? E MET 109 
485 1 Y 1 D LEU 4    ? E LEU 110 
486 1 Y 1 D HIS 5    ? E HIS 111 
487 1 Y 1 D PRO 6    ? E PRO 112 
488 1 Y 1 D SER 7    ? E SER 113 
489 1 Y 1 D SER 8    ? E SER 114 
490 1 Y 1 D VAL 9    ? E VAL 115 
491 1 Y 1 D SER 10   ? E SER 116 
492 1 Y 1 D THR 11   ? E THR 117 
493 1 Y 1 D THR 12   ? E THR 118 
494 1 Y 1 D SER 13   ? E SER 119 
495 1 Y 1 D GLU 14   ? E GLU 120 
496 1 Y 1 D PRO 15   ? E PRO 121 
497 1 Y 1 D GLU 16   ? E GLU 122 
498 1 Y 1 D ASN 17   ? E ASN 123 
499 1 Y 1 D ALA 18   ? E ALA 124 
500 1 Y 1 D SER 19   ? E SER 125 
501 1 Y 1 D SER 20   ? E SER 126 
502 1 Y 1 D ALA 21   ? E ALA 127 
503 1 Y 1 D TRP 22   ? E TRP 128 
504 1 Y 1 D PRO 23   ? E PRO 129 
505 1 Y 1 D PRO 24   ? E PRO 130 
506 1 Y 1 D ASP 25   ? E ASP 131 
507 1 Y 1 D ALA 26   ? E ALA 132 
508 1 Y 1 D THR 27   ? E THR 133 
509 1 Y 1 D LEU 28   ? E LEU 134 
510 1 Y 1 D GLY 29   ? E GLY 135 
511 1 Y 1 D ASN 30   ? E ASN 136 
512 1 Y 1 D VAL 31   ? E VAL 137 
513 1 Y 1 D SER 32   ? E SER 138 
514 1 Y 1 D ALA 33   ? E ALA 139 
515 1 Y 1 D GLY 34   ? E GLY 140 
516 1 Y 1 D PRO 35   ? E PRO 141 
517 1 Y 1 D SER 36   ? E SER 142 
518 1 Y 1 D PRO 37   ? E PRO 143 
519 1 Y 1 D ALA 38   ? E ALA 144 
520 1 Y 1 D GLY 39   ? E GLY 145 
521 1 Y 1 D LEU 40   ? E LEU 146 
522 1 Y 1 D PRO 243  ? E PRO 349 
523 1 Y 1 D SER 244  ? E SER 350 
524 1 Y 1 D CYS 245  ? E CYS 351 
525 1 Y 1 D GLN 246  ? E GLN 352 
526 1 Y 1 D ARG 326  ? E ARG 432 
527 1 Y 1 D VAL 327  ? E VAL 433 
528 1 Y 1 D LEU 328  ? E LEU 434 
529 1 Y 1 D LEU 329  ? E LEU 435 
530 1 Y 1 D ARG 330  ? E ARG 436 
531 1 Y 1 D PRO 331  ? E PRO 437 
532 1 Y 1 D SER 332  ? E SER 438 
533 1 Y 1 D ARG 333  ? E ARG 439 
534 1 Y 1 D ARG 334  ? E ARG 440 
535 1 Y 1 D VAL 335  ? E VAL 441 
536 1 Y 1 D ARG 336  ? E ARG 442 
537 1 Y 1 D SER 337  ? E SER 443 
538 1 Y 1 D GLN 338  ? E GLN 444 
539 1 Y 1 D GLU 339  ? E GLU 445 
540 1 Y 1 D PRO 340  ? E PRO 446 
541 1 Y 1 D THR 341  ? E THR 447 
542 1 Y 1 D VAL 342  ? E VAL 448 
543 1 Y 1 D GLY 343  ? E GLY 449 
544 1 Y 1 D PRO 344  ? E PRO 450 
545 1 Y 1 D PRO 345  ? E PRO 451 
546 1 Y 1 D GLU 346  ? E GLU 452 
547 1 Y 1 D LYS 347  ? E LYS 453 
548 1 Y 1 D THR 348  ? E THR 454 
549 1 Y 1 D GLU 349  ? E GLU 455 
550 1 Y 1 D GLU 350  ? E GLU 456 
551 1 Y 1 D GLU 351  ? E GLU 457 
552 1 Y 1 D ASP 352  ? E ASP 458 
553 1 Y 1 D GLU 353  ? E GLU 459 
554 1 Y 1 D GLU 354  ? E GLU 460 
555 1 Y 1 D GLU 355  ? E GLU 461 
556 1 Y 1 D GLU 356  ? E GLU 462 
557 1 Y 1 D ASP 357  ? E ASP 463 
558 1 Y 1 D GLY 358  ? E GLY 464 
559 1 Y 1 D GLU 359  ? E GLU 465 
560 1 Y 1 D GLU 360  ? E GLU 466 
561 1 Y 1 D SER 361  ? E SER 467 
562 1 Y 1 D ARG 362  ? E ARG 468 
563 1 Y 1 D GLU 363  ? E GLU 469 
564 1 Y 1 D GLY 364  ? E GLY 470 
565 1 Y 1 D GLY 365  ? E GLY 471 
566 1 Y 1 D LYS 366  ? E LYS 472 
567 1 Y 1 D GLY 367  ? E GLY 473 
568 1 Y 1 D LYS 368  ? E LYS 474 
569 1 Y 1 D GLU 369  ? E GLU 475 
570 1 Y 1 D MET 370  ? E MET 476 
571 1 Y 1 D ASN 371  ? E ASN 477 
572 1 Y 1 D GLY 372  ? E GLY 478 
573 1 Y 1 D ARG 373  ? E ARG 479 
574 1 Y 1 D VAL 374  ? E VAL 480 
575 1 Y 1 D SER 375  ? E SER 481 
576 1 Y 1 D GLN 376  ? E GLN 482 
577 1 Y 1 D ILE 377  ? E ILE 483 
578 1 Y 1 D THR 378  ? E THR 484 
579 1 Y 1 D GLN 379  ? E GLN 485 
580 1 Y 1 D PRO 380  ? E PRO 486 
581 1 Y 1 D GLY 381  ? E GLY 487 
582 1 Y 1 D THR 382  ? E THR 488 
583 1 Y 1 D SER 383  ? E SER 489 
584 1 Y 1 D GLY 384  ? E GLY 490 
585 1 Y 1 D GLN 385  ? E GLN 491 
586 1 Y 1 D GLU 386  ? E GLU 492 
587 1 Y 1 D ARG 387  ? E ARG 493 
588 1 Y 1 D PRO 388  ? E PRO 494 
589 1 Y 1 D PRO 389  ? E PRO 495 
590 1 Y 1 D SER 390  ? E SER 496 
591 1 Y 1 D ARG 391  ? E ARG 497 
592 1 Y 1 D VAL 392  ? E VAL 498 
593 1 Y 1 D ALA 393  ? E ALA 499 
594 1 Y 1 D SER 394  ? E SER 500 
595 1 Y 1 D LYS 395  ? E LYS 501 
596 1 Y 1 D GLU 396  ? E GLU 502 
597 1 Y 1 D GLN 397  ? E GLN 503 
598 1 Y 1 D GLN 398  ? E GLN 504 
599 1 Y 1 D LEU 399  ? E LEU 505 
600 1 Y 1 D LEU 400  ? E LEU 506 
601 1 Y 1 D PRO 401  ? E PRO 507 
602 1 Y 1 D GLN 402  ? E GLN 508 
603 1 Y 1 D GLU 403  ? E GLU 509 
604 1 Y 1 D ALA 404  ? E ALA 510 
605 1 Y 1 D SER 405  ? E SER 511 
606 1 Y 1 D THR 406  ? E THR 512 
607 1 Y 1 D GLY 407  ? E GLY 513 
608 1 Y 1 D GLU 408  ? E GLU 514 
609 1 Y 1 D LYS 409  ? E LYS 515 
610 1 Y 1 D SER 410  ? E SER 516 
611 1 Y 1 D SER 411  ? E SER 517 
612 1 Y 1 D THR 412  ? E THR 518 
613 1 Y 1 D MET 413  ? E MET 519 
614 1 Y 1 D ARG 414  ? E ARG 520 
615 1 Y 1 D ILE 415  ? E ILE 521 
616 1 Y 1 D SER 416  ? E SER 522 
617 1 Y 1 D TYR 417  ? E TYR 523 
618 1 Y 1 D LEU 418  ? E LEU 524 
619 1 Y 1 S ALA 1    ? F ALA 1   
620 1 Y 1 S GLY 2    ? F GLY 2   
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
PHE N    N N N 247 
PHE CA   C N S 248 
PHE C    C N N 249 
PHE O    O N N 250 
PHE CB   C N N 251 
PHE CG   C Y N 252 
PHE CD1  C Y N 253 
PHE CD2  C Y N 254 
PHE CE1  C Y N 255 
PHE CE2  C Y N 256 
PHE CZ   C Y N 257 
PHE OXT  O N N 258 
PHE H    H N N 259 
PHE H2   H N N 260 
PHE HA   H N N 261 
PHE HB2  H N N 262 
PHE HB3  H N N 263 
PHE HD1  H N N 264 
PHE HD2  H N N 265 
PHE HE1  H N N 266 
PHE HE2  H N N 267 
PHE HZ   H N N 268 
PHE HXT  H N N 269 
PRO N    N N N 270 
PRO CA   C N S 271 
PRO C    C N N 272 
PRO O    O N N 273 
PRO CB   C N N 274 
PRO CG   C N N 275 
PRO CD   C N N 276 
PRO OXT  O N N 277 
PRO H    H N N 278 
PRO HA   H N N 279 
PRO HB2  H N N 280 
PRO HB3  H N N 281 
PRO HG2  H N N 282 
PRO HG3  H N N 283 
PRO HD2  H N N 284 
PRO HD3  H N N 285 
PRO HXT  H N N 286 
SER N    N N N 287 
SER CA   C N S 288 
SER C    C N N 289 
SER O    O N N 290 
SER CB   C N N 291 
SER OG   O N N 292 
SER OXT  O N N 293 
SER H    H N N 294 
SER H2   H N N 295 
SER HA   H N N 296 
SER HB2  H N N 297 
SER HB3  H N N 298 
SER HG   H N N 299 
SER HXT  H N N 300 
THR N    N N N 301 
THR CA   C N S 302 
THR C    C N N 303 
THR O    O N N 304 
THR CB   C N R 305 
THR OG1  O N N 306 
THR CG2  C N N 307 
THR OXT  O N N 308 
THR H    H N N 309 
THR H2   H N N 310 
THR HA   H N N 311 
THR HB   H N N 312 
THR HG1  H N N 313 
THR HG21 H N N 314 
THR HG22 H N N 315 
THR HG23 H N N 316 
THR HXT  H N N 317 
TRP N    N N N 318 
TRP CA   C N S 319 
TRP C    C N N 320 
TRP O    O N N 321 
TRP CB   C N N 322 
TRP CG   C Y N 323 
TRP CD1  C Y N 324 
TRP CD2  C Y N 325 
TRP NE1  N Y N 326 
TRP CE2  C Y N 327 
TRP CE3  C Y N 328 
TRP CZ2  C Y N 329 
TRP CZ3  C Y N 330 
TRP CH2  C Y N 331 
TRP OXT  O N N 332 
TRP H    H N N 333 
TRP H2   H N N 334 
TRP HA   H N N 335 
TRP HB2  H N N 336 
TRP HB3  H N N 337 
TRP HD1  H N N 338 
TRP HE1  H N N 339 
TRP HE3  H N N 340 
TRP HZ2  H N N 341 
TRP HZ3  H N N 342 
TRP HH2  H N N 343 
TRP HXT  H N N 344 
TYR N    N N N 345 
TYR CA   C N S 346 
TYR C    C N N 347 
TYR O    O N N 348 
TYR CB   C N N 349 
TYR CG   C Y N 350 
TYR CD1  C Y N 351 
TYR CD2  C Y N 352 
TYR CE1  C Y N 353 
TYR CE2  C Y N 354 
TYR CZ   C Y N 355 
TYR OH   O N N 356 
TYR OXT  O N N 357 
TYR H    H N N 358 
TYR H2   H N N 359 
TYR HA   H N N 360 
TYR HB2  H N N 361 
TYR HB3  H N N 362 
TYR HD1  H N N 363 
TYR HD2  H N N 364 
TYR HE1  H N N 365 
TYR HE2  H N N 366 
TYR HH   H N N 367 
TYR HXT  H N N 368 
VAL N    N N N 369 
VAL CA   C N S 370 
VAL C    C N N 371 
VAL O    O N N 372 
VAL CB   C N N 373 
VAL CG1  C N N 374 
VAL CG2  C N N 375 
VAL OXT  O N N 376 
VAL H    H N N 377 
VAL H2   H N N 378 
VAL HA   H N N 379 
VAL HB   H N N 380 
VAL HG11 H N N 381 
VAL HG12 H N N 382 
VAL HG13 H N N 383 
VAL HG21 H N N 384 
VAL HG22 H N N 385 
VAL HG23 H N N 386 
VAL HXT  H N N 387 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SER N   CA   sing N N 275 
SER N   H    sing N N 276 
SER N   H2   sing N N 277 
SER CA  C    sing N N 278 
SER CA  CB   sing N N 279 
SER CA  HA   sing N N 280 
SER C   O    doub N N 281 
SER C   OXT  sing N N 282 
SER CB  OG   sing N N 283 
SER CB  HB2  sing N N 284 
SER CB  HB3  sing N N 285 
SER OG  HG   sing N N 286 
SER OXT HXT  sing N N 287 
THR N   CA   sing N N 288 
THR N   H    sing N N 289 
THR N   H2   sing N N 290 
THR CA  C    sing N N 291 
THR CA  CB   sing N N 292 
THR CA  HA   sing N N 293 
THR C   O    doub N N 294 
THR C   OXT  sing N N 295 
THR CB  OG1  sing N N 296 
THR CB  CG2  sing N N 297 
THR CB  HB   sing N N 298 
THR OG1 HG1  sing N N 299 
THR CG2 HG21 sing N N 300 
THR CG2 HG22 sing N N 301 
THR CG2 HG23 sing N N 302 
THR OXT HXT  sing N N 303 
TRP N   CA   sing N N 304 
TRP N   H    sing N N 305 
TRP N   H2   sing N N 306 
TRP CA  C    sing N N 307 
TRP CA  CB   sing N N 308 
TRP CA  HA   sing N N 309 
TRP C   O    doub N N 310 
TRP C   OXT  sing N N 311 
TRP CB  CG   sing N N 312 
TRP CB  HB2  sing N N 313 
TRP CB  HB3  sing N N 314 
TRP CG  CD1  doub Y N 315 
TRP CG  CD2  sing Y N 316 
TRP CD1 NE1  sing Y N 317 
TRP CD1 HD1  sing N N 318 
TRP CD2 CE2  doub Y N 319 
TRP CD2 CE3  sing Y N 320 
TRP NE1 CE2  sing Y N 321 
TRP NE1 HE1  sing N N 322 
TRP CE2 CZ2  sing Y N 323 
TRP CE3 CZ3  doub Y N 324 
TRP CE3 HE3  sing N N 325 
TRP CZ2 CH2  doub Y N 326 
TRP CZ2 HZ2  sing N N 327 
TRP CZ3 CH2  sing Y N 328 
TRP CZ3 HZ3  sing N N 329 
TRP CH2 HH2  sing N N 330 
TRP OXT HXT  sing N N 331 
TYR N   CA   sing N N 332 
TYR N   H    sing N N 333 
TYR N   H2   sing N N 334 
TYR CA  C    sing N N 335 
TYR CA  CB   sing N N 336 
TYR CA  HA   sing N N 337 
TYR C   O    doub N N 338 
TYR C   OXT  sing N N 339 
TYR CB  CG   sing N N 340 
TYR CB  HB2  sing N N 341 
TYR CB  HB3  sing N N 342 
TYR CG  CD1  doub Y N 343 
TYR CG  CD2  sing Y N 344 
TYR CD1 CE1  sing Y N 345 
TYR CD1 HD1  sing N N 346 
TYR CD2 CE2  doub Y N 347 
TYR CD2 HD2  sing N N 348 
TYR CE1 CZ   doub Y N 349 
TYR CE1 HE1  sing N N 350 
TYR CE2 CZ   sing Y N 351 
TYR CE2 HE2  sing N N 352 
TYR CZ  OH   sing N N 353 
TYR OH  HH   sing N N 354 
TYR OXT HXT  sing N N 355 
VAL N   CA   sing N N 356 
VAL N   H    sing N N 357 
VAL N   H2   sing N N 358 
VAL CA  C    sing N N 359 
VAL CA  CB   sing N N 360 
VAL CA  HA   sing N N 361 
VAL C   O    doub N N 362 
VAL C   OXT  sing N N 363 
VAL CB  CG1  sing N N 364 
VAL CB  CG2  sing N N 365 
VAL CB  HB   sing N N 366 
VAL CG1 HG11 sing N N 367 
VAL CG1 HG12 sing N N 368 
VAL CG1 HG13 sing N N 369 
VAL CG2 HG21 sing N N 370 
VAL CG2 HG22 sing N N 371 
VAL CG2 HG23 sing N N 372 
VAL OXT HXT  sing N N 373 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-04-26 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           8ZBI 
_em_admin.last_update        2025-04-30 
_em_admin.map_release_date   2025-04-30 
_em_admin.title              'Cryo-EM structure of Somatostatin receptor 3 (SSTR3) with Gi1 complex' 
# 
loop_
_em_buffer_component.buffer_id 
_em_buffer_component.concentration 
_em_buffer_component.concentration_units 
_em_buffer_component.formula 
_em_buffer_component.id 
_em_buffer_component.name 
1 20     mM       HEPES 1 '2-[4-(2-Hydroxyethyl)-1-piperazinyl]ethanesulfonic acid' 
1 100    mM       NaCl  2 'sodium chloride'                                         
1 1      mM       MgCl2 3 'magnesium chloride'                                      
1 0.5    mM       TCEP  4 'Tris(2-carboxyethyl)phosphine'                           
1 0.001  '%(w/v)' LMNG  5 'Lauryl Maltose Neopentyl Glycol'                         
1 0.0001 '%(w/v)' CHS   6 'Cholesteryl Hemisuccinate Tris Salt'                     
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     NONE 
# 
_em_entity_assembly_molwt.entity_assembly_id   1 
_em_entity_assembly_molwt.experimental_flag    NO 
_em_entity_assembly_molwt.id                   1 
_em_entity_assembly_molwt.units                MEGADALTONS 
_em_entity_assembly_molwt.value                0.15 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          7108 
_em_entity_assembly_recombinant.organism             'Spodoptera frugiperda' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         67.7 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 BIOQUANTUM (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    1 
_em_image_recording.num_real_images                     15462 
# 
_em_particle_selection.details                  ? 
_em_particle_selection.id                       1 
_em_particle_selection.image_processing_id      1 
_em_particle_selection.method                   ? 
_em_particle_selection.num_particles_selected   11354254 
_em_particle_selection.reference_model          ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? cryoSPARC v3.3.2 
'IMAGE ACQUISITION'        ? 2  ? ? 1 ?         ?      
MASKING                    ? 3  ? ? ? ?         ?      
'CTF CORRECTION'           ? 4  1 ? ? ?         ?      
'LAYERLINE INDEXING'       ? 5  ? ? ? ?         ?      
'DIFFRACTION INDEXING'     ? 6  ? ? ? ?         ?      
'MODEL FITTING'            ? 7  ? 1 ? Coot      0.9.5  
OTHER                      ? 8  ? ? ? ?         ?      
'INITIAL EULER ASSIGNMENT' ? 9  1 ? ? cryoSPARC 3.3.2  
'FINAL EULER ASSIGNMENT'   ? 10 1 ? ? cryoSPARC 3.3.2  
CLASSIFICATION             ? 11 1 ? ? ?         ?      
RECONSTRUCTION             ? 12 1 ? ? cryoSPARC ?      
'MODEL REFINEMENT'         ? 13 ? 1 ? PHENIX    1.19.2 
# 
_em_specimen.concentration           3.0 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'Institute for Basic Science' 'Korea, Republic Of' IBS-R021-D1-2023-a00 1 
'Institute for Basic Science' 'Korea, Republic Of' IBS-R021-D1-2024-a00 2 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   7WJ5 
# 
_atom_sites.entry_id                    8ZBI 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM 1    N N   . LEU A 1 5   ? 97.398  84.805  95.165  1.00 38.54  ? 5   LEU B N   1 
ATOM 2    C CA  . LEU A 1 5   ? 98.042  85.215  93.885  1.00 38.26  ? 5   LEU B CA  1 
ATOM 3    C C   . LEU A 1 5   ? 98.391  84.008  93.030  1.00 36.41  ? 5   LEU B C   1 
ATOM 4    O O   . LEU A 1 5   ? 98.562  82.902  93.538  1.00 32.26  ? 5   LEU B O   1 
ATOM 5    C CB  . LEU A 1 5   ? 99.307  86.030  94.155  1.00 34.29  ? 5   LEU B CB  1 
ATOM 6    C CG  . LEU A 1 5   ? 99.131  87.420  94.762  1.00 37.59  ? 5   LEU B CG  1 
ATOM 7    C CD1 . LEU A 1 5   ? 100.489 88.053  95.019  1.00 35.30  ? 5   LEU B CD1 1 
ATOM 8    C CD2 . LEU A 1 5   ? 98.290  88.304  93.860  1.00 35.28  ? 5   LEU B CD2 1 
ATOM 9    N N   . SER A 1 6   ? 98.496  84.235  91.724  1.00 32.31  ? 6   SER B N   1 
ATOM 10   C CA  . SER A 1 6   ? 98.913  83.207  90.789  1.00 34.89  ? 6   SER B CA  1 
ATOM 11   C C   . SER A 1 6   ? 100.423 83.290  90.570  1.00 33.03  ? 6   SER B C   1 
ATOM 12   O O   . SER A 1 6   ? 101.115 84.144  91.130  1.00 26.67  ? 6   SER B O   1 
ATOM 13   C CB  . SER A 1 6   ? 98.146  83.349  89.477  1.00 24.79  ? 6   SER B CB  1 
ATOM 14   O OG  . SER A 1 6   ? 98.180  84.684  89.014  1.00 32.25  ? 6   SER B OG  1 
ATOM 15   N N   . ALA A 1 7   ? 100.948 82.382  89.746  1.00 35.83  ? 7   ALA B N   1 
ATOM 16   C CA  . ALA A 1 7   ? 102.382 82.361  89.485  1.00 31.08  ? 7   ALA B CA  1 
ATOM 17   C C   . ALA A 1 7   ? 102.846 83.571  88.685  1.00 41.55  ? 7   ALA B C   1 
ATOM 18   O O   . ALA A 1 7   ? 104.026 83.928  88.760  1.00 32.98  ? 7   ALA B O   1 
ATOM 19   C CB  . ALA A 1 7   ? 102.759 81.075  88.748  1.00 29.81  ? 7   ALA B CB  1 
ATOM 20   N N   . GLU A 1 8   ? 101.951 84.208  87.926  1.00 28.92  ? 8   GLU B N   1 
ATOM 21   C CA  . GLU A 1 8   ? 102.318 85.361  87.113  1.00 19.42  ? 8   GLU B CA  1 
ATOM 22   C C   . GLU A 1 8   ? 102.161 86.684  87.851  1.00 24.72  ? 8   GLU B C   1 
ATOM 23   O O   . GLU A 1 8   ? 102.950 87.609  87.622  1.00 22.53  ? 8   GLU B O   1 
ATOM 24   C CB  . GLU A 1 8   ? 101.479 85.385  85.836  1.00 24.42  ? 8   GLU B CB  1 
ATOM 25   C CG  . GLU A 1 8   ? 101.699 84.184  84.930  1.00 25.90  ? 8   GLU B CG  1 
ATOM 26   C CD  . GLU A 1 8   ? 101.137 84.385  83.534  1.00 28.13  ? 8   GLU B CD  1 
ATOM 27   O OE1 . GLU A 1 8   ? 100.915 85.546  83.138  1.00 27.01  ? 8   GLU B OE1 1 
ATOM 28   O OE2 . GLU A 1 8   ? 100.915 83.381  82.830  1.00 35.54  ? 8   GLU B OE2 1 
ATOM 29   N N   . ASP A 1 9   ? 101.167 86.797  88.733  1.00 30.49  ? 9   ASP B N   1 
ATOM 30   C CA  . ASP A 1 9   ? 101.051 87.995  89.559  1.00 23.66  ? 9   ASP B CA  1 
ATOM 31   C C   . ASP A 1 9   ? 102.257 88.142  90.476  1.00 28.64  ? 9   ASP B C   1 
ATOM 32   O O   . ASP A 1 9   ? 102.738 89.255  90.713  1.00 41.76  ? 9   ASP B O   1 
ATOM 33   C CB  . ASP A 1 9   ? 99.763  87.947  90.375  1.00 23.27  ? 9   ASP B CB  1 
ATOM 34   C CG  . ASP A 1 9   ? 98.523  88.000  89.511  1.00 34.65  ? 9   ASP B CG  1 
ATOM 35   O OD1 . ASP A 1 9   ? 98.660  88.010  88.270  1.00 29.37  ? 9   ASP B OD1 1 
ATOM 36   O OD2 . ASP A 1 9   ? 97.407  88.033  90.074  1.00 38.35  ? 9   ASP B OD2 1 
ATOM 37   N N   . LYS A 1 10  ? 102.761 87.027  91.002  1.00 27.38  ? 10  LYS B N   1 
ATOM 38   C CA  . LYS A 1 10  ? 103.959 87.081  91.829  1.00 29.46  ? 10  LYS B CA  1 
ATOM 39   C C   . LYS A 1 10  ? 105.159 87.573  91.028  1.00 29.06  ? 10  LYS B C   1 
ATOM 40   O O   . LYS A 1 10  ? 105.973 88.352  91.535  1.00 33.90  ? 10  LYS B O   1 
ATOM 41   C CB  . LYS A 1 10  ? 104.237 85.704  92.427  1.00 35.45  ? 10  LYS B CB  1 
ATOM 42   C CG  . LYS A 1 10  ? 103.162 85.223  93.394  1.00 36.98  ? 10  LYS B CG  1 
ATOM 43   C CD  . LYS A 1 10  ? 103.411 83.795  93.865  1.00 34.28  ? 10  LYS B CD  1 
ATOM 44   C CE  . LYS A 1 10  ? 104.759 83.644  94.548  1.00 36.05  ? 10  LYS B CE  1 
ATOM 45   N NZ  . LYS A 1 10  ? 104.982 84.667  95.606  1.00 35.37  ? 10  LYS B NZ  1 
ATOM 46   N N   . ALA A 1 11  ? 105.291 87.125  89.776  1.00 23.72  ? 11  ALA B N   1 
ATOM 47   C CA  . ALA A 1 11  ? 106.386 87.597  88.933  1.00 23.83  ? 11  ALA B CA  1 
ATOM 48   C C   . ALA A 1 11  ? 106.247 89.083  88.628  1.00 31.52  ? 11  ALA B C   1 
ATOM 49   O O   . ALA A 1 11  ? 107.245 89.816  88.583  1.00 29.25  ? 11  ALA B O   1 
ATOM 50   C CB  . ALA A 1 11  ? 106.434 86.785  87.641  1.00 20.52  ? 11  ALA B CB  1 
ATOM 51   N N   . ALA A 1 12  ? 105.014 89.546  88.410  1.00 31.17  ? 12  ALA B N   1 
ATOM 52   C CA  . ALA A 1 12  ? 104.788 90.972  88.208  1.00 12.47  ? 12  ALA B CA  1 
ATOM 53   C C   . ALA A 1 12  ? 105.174 91.769  89.449  1.00 22.66  ? 12  ALA B C   1 
ATOM 54   O O   . ALA A 1 12  ? 105.739 92.863  89.344  1.00 35.72  ? 12  ALA B O   1 
ATOM 55   C CB  . ALA A 1 12  ? 103.330 91.222  87.837  1.00 2.80   ? 12  ALA B CB  1 
ATOM 56   N N   . VAL A 1 13  ? 104.880 91.236  90.637  1.00 29.37  ? 13  VAL B N   1 
ATOM 57   C CA  . VAL A 1 13  ? 105.269 91.918  91.870  1.00 28.46  ? 13  VAL B CA  1 
ATOM 58   C C   . VAL A 1 13  ? 106.787 91.931  92.021  1.00 28.19  ? 13  VAL B C   1 
ATOM 59   O O   . VAL A 1 13  ? 107.365 92.902  92.523  1.00 30.81  ? 13  VAL B O   1 
ATOM 60   C CB  . VAL A 1 13  ? 104.585 91.265  93.084  1.00 28.25  ? 13  VAL B CB  1 
ATOM 61   C CG1 . VAL A 1 13  ? 105.135 91.840  94.375  1.00 28.83  ? 13  VAL B CG1 1 
ATOM 62   C CG2 . VAL A 1 13  ? 103.080 91.466  93.021  1.00 29.27  ? 13  VAL B CG2 1 
ATOM 63   N N   . GLU A 1 14  ? 107.456 90.852  91.608  1.00 34.21  ? 14  GLU B N   1 
ATOM 64   C CA  . GLU A 1 14  ? 108.918 90.845  91.619  1.00 29.18  ? 14  GLU B CA  1 
ATOM 65   C C   . GLU A 1 14  ? 109.476 91.933  90.710  1.00 36.74  ? 14  GLU B C   1 
ATOM 66   O O   . GLU A 1 14  ? 110.421 92.644  91.079  1.00 39.20  ? 14  GLU B O   1 
ATOM 67   C CB  . GLU A 1 14  ? 109.443 89.482  91.175  1.00 24.80  ? 14  GLU B CB  1 
ATOM 68   C CG  . GLU A 1 14  ? 109.081 88.326  92.075  1.00 23.49  ? 14  GLU B CG  1 
ATOM 69   C CD  . GLU A 1 14  ? 109.292 86.987  91.397  1.00 39.93  ? 14  GLU B CD  1 
ATOM 70   O OE1 . GLU A 1 14  ? 110.205 86.889  90.551  1.00 36.44  ? 14  GLU B OE1 1 
ATOM 71   O OE2 . GLU A 1 14  ? 108.543 86.036  91.702  1.00 43.16  ? 14  GLU B OE2 1 
ATOM 72   N N   . ARG A 1 15  ? 108.909 92.064  89.507  1.00 25.29  ? 15  ARG B N   1 
ATOM 73   C CA  . ARG A 1 15  ? 109.341 93.116  88.593  1.00 19.16  ? 15  ARG B CA  1 
ATOM 74   C C   . ARG A 1 15  ? 109.106 94.495  89.194  1.00 22.82  ? 15  ARG B C   1 
ATOM 75   O O   . ARG A 1 15  ? 109.945 95.393  89.058  1.00 19.07  ? 15  ARG B O   1 
ATOM 76   C CB  . ARG A 1 15  ? 108.606 92.980  87.260  1.00 21.93  ? 15  ARG B CB  1 
ATOM 77   C CG  . ARG A 1 15  ? 108.441 94.279  86.488  1.00 21.64  ? 15  ARG B CG  1 
ATOM 78   C CD  . ARG A 1 15  ? 107.739 94.045  85.181  1.00 18.62  ? 15  ARG B CD  1 
ATOM 79   N NE  . ARG A 1 15  ? 108.667 93.859  84.073  1.00 32.19  ? 15  ARG B NE  1 
ATOM 80   C CZ  . ARG A 1 15  ? 109.018 94.801  83.208  1.00 23.33  ? 15  ARG B CZ  1 
ATOM 81   N NH1 . ARG A 1 15  ? 108.544 96.034  83.290  1.00 19.43  ? 15  ARG B NH1 1 
ATOM 82   N NH2 . ARG A 1 15  ? 109.867 94.498  82.232  1.00 23.56  ? 15  ARG B NH2 1 
ATOM 83   N N   . SER A 1 16  ? 107.957 94.686  89.844  1.00 26.66  ? 16  SER B N   1 
ATOM 84   C CA  . SER A 1 16  ? 107.669 95.968  90.475  1.00 22.08  ? 16  SER B CA  1 
ATOM 85   C C   . SER A 1 16  ? 108.677 96.277  91.574  1.00 27.82  ? 16  SER B C   1 
ATOM 86   O O   . SER A 1 16  ? 109.121 97.421  91.717  1.00 35.20  ? 16  SER B O   1 
ATOM 87   C CB  . SER A 1 16  ? 106.250 95.965  91.033  1.00 17.43  ? 16  SER B CB  1 
ATOM 88   O OG  . SER A 1 16  ? 105.958 97.195  91.665  1.00 28.99  ? 16  SER B OG  1 
ATOM 89   N N   . LYS A 1 17  ? 109.050 95.268  92.364  1.00 36.59  ? 17  LYS B N   1 
ATOM 90   C CA  . LYS A 1 17  ? 110.063 95.473  93.394  1.00 29.26  ? 17  LYS B CA  1 
ATOM 91   C C   . LYS A 1 17  ? 111.407 95.848  92.782  1.00 28.19  ? 17  LYS B C   1 
ATOM 92   O O   . LYS A 1 17  ? 112.115 96.714  93.305  1.00 32.57  ? 17  LYS B O   1 
ATOM 93   C CB  . LYS A 1 17  ? 110.203 94.220  94.254  1.00 35.81  ? 17  LYS B CB  1 
ATOM 94   C CG  . LYS A 1 17  ? 109.032 93.963  95.189  1.00 37.60  ? 17  LYS B CG  1 
ATOM 95   C CD  . LYS A 1 17  ? 109.440 93.091  96.371  1.00 36.69  ? 17  LYS B CD  1 
ATOM 96   C CE  . LYS A 1 17  ? 109.765 91.664  95.950  1.00 35.75  ? 17  LYS B CE  1 
ATOM 97   N NZ  . LYS A 1 17  ? 108.544 90.865  95.655  1.00 32.25  ? 17  LYS B NZ  1 
ATOM 98   N N   . MET A 1 18  ? 111.785 95.196  91.680  1.00 33.73  ? 18  MET B N   1 
ATOM 99   C CA  . MET A 1 18  ? 113.041 95.552  91.021  1.00 40.33  ? 18  MET B CA  1 
ATOM 100  C C   . MET A 1 18  ? 113.008 96.988  90.506  1.00 47.20  ? 18  MET B C   1 
ATOM 101  O O   . MET A 1 18  ? 113.998 97.725  90.621  1.00 47.97  ? 18  MET B O   1 
ATOM 102  C CB  . MET A 1 18  ? 113.325 94.582  89.877  1.00 38.67  ? 18  MET B CB  1 
ATOM 103  C CG  . MET A 1 18  ? 113.651 93.175  90.332  1.00 42.41  ? 18  MET B CG  1 
ATOM 104  S SD  . MET A 1 18  ? 114.395 92.168  89.040  1.00 61.43  ? 18  MET B SD  1 
ATOM 105  C CE  . MET A 1 18  ? 116.012 92.924  88.900  1.00 43.34  ? 18  MET B CE  1 
ATOM 106  N N   . ILE A 1 19  ? 111.878 97.401  89.926  1.00 39.99  ? 19  ILE B N   1 
ATOM 107  C CA  . ILE A 1 19  ? 111.733 98.783  89.477  1.00 35.32  ? 19  ILE B CA  1 
ATOM 108  C C   . ILE A 1 19  ? 111.856 99.735  90.658  1.00 37.16  ? 19  ILE B C   1 
ATOM 109  O O   . ILE A 1 19  ? 112.462 100.806 90.548  1.00 40.54  ? 19  ILE B O   1 
ATOM 110  C CB  . ILE A 1 19  ? 110.397 98.971  88.732  1.00 39.34  ? 19  ILE B CB  1 
ATOM 111  C CG1 . ILE A 1 19  ? 110.416 98.208  87.404  1.00 35.76  ? 19  ILE B CG1 1 
ATOM 112  C CG2 . ILE A 1 19  ? 110.116 100.452 88.490  1.00 36.24  ? 19  ILE B CG2 1 
ATOM 113  C CD1 . ILE A 1 19  ? 109.087 98.171  86.689  1.00 30.79  ? 19  ILE B CD1 1 
ATOM 114  N N   . ASP A 1 20  ? 111.270 99.369  91.801  1.00 41.64  ? 20  ASP B N   1 
ATOM 115  C CA  . ASP A 1 20  ? 111.394 100.198 92.998  1.00 41.05  ? 20  ASP B CA  1 
ATOM 116  C C   . ASP A 1 20  ? 112.848 100.333 93.431  1.00 42.94  ? 20  ASP B C   1 
ATOM 117  O O   . ASP A 1 20  ? 113.300 101.429 93.786  1.00 50.58  ? 20  ASP B O   1 
ATOM 118  C CB  . ASP A 1 20  ? 110.560 99.606  94.133  1.00 40.74  ? 20  ASP B CB  1 
ATOM 119  C CG  . ASP A 1 20  ? 109.120 100.070 94.108  1.00 48.52  ? 20  ASP B CG  1 
ATOM 120  O OD1 . ASP A 1 20  ? 108.888 101.289 93.960  1.00 43.70  ? 20  ASP B OD1 1 
ATOM 121  O OD2 . ASP A 1 20  ? 108.219 99.215  94.243  1.00 45.37  ? 20  ASP B OD2 1 
ATOM 122  N N   . ARG A 1 21  ? 113.594 99.228  93.420  1.00 47.50  ? 21  ARG B N   1 
ATOM 123  C CA  . ARG A 1 21  ? 115.003 99.292  93.798  1.00 50.16  ? 21  ARG B CA  1 
ATOM 124  C C   . ARG A 1 21  ? 115.775 100.211 92.863  1.00 52.49  ? 21  ARG B C   1 
ATOM 125  O O   . ARG A 1 21  ? 116.584 101.034 93.312  1.00 56.76  ? 21  ARG B O   1 
ATOM 126  C CB  . ARG A 1 21  ? 115.624 97.895  93.792  1.00 51.78  ? 21  ARG B CB  1 
ATOM 127  C CG  . ARG A 1 21  ? 114.991 96.908  94.755  1.00 51.77  ? 21  ARG B CG  1 
ATOM 128  C CD  . ARG A 1 21  ? 115.814 95.639  94.874  1.00 51.69  ? 21  ARG B CD  1 
ATOM 129  N NE  . ARG A 1 21  ? 114.972 94.469  95.108  1.00 54.20  ? 21  ARG B NE  1 
ATOM 130  C CZ  . ARG A 1 21  ? 114.883 93.413  94.307  1.00 56.65  ? 21  ARG B CZ  1 
ATOM 131  N NH1 . ARG A 1 21  ? 115.625 93.298  93.217  1.00 52.94  ? 21  ARG B NH1 1 
ATOM 132  N NH2 . ARG A 1 21  ? 114.030 92.439  94.614  1.00 53.16  ? 21  ARG B NH2 1 
ATOM 133  N N   . ASN A 1 22  ? 115.539 100.089 91.555  1.00 50.66  ? 22  ASN B N   1 
ATOM 134  C CA  . ASN A 1 22  ? 116.259 100.930 90.602  1.00 47.70  ? 22  ASN B CA  1 
ATOM 135  C C   . ASN A 1 22  ? 115.876 102.399 90.752  1.00 50.51  ? 22  ASN B C   1 
ATOM 136  O O   . ASN A 1 22  ? 116.730 103.285 90.629  1.00 50.26  ? 22  ASN B O   1 
ATOM 137  C CB  . ASN A 1 22  ? 116.004 100.446 89.179  1.00 51.66  ? 22  ASN B CB  1 
ATOM 138  C CG  . ASN A 1 22  ? 116.794 99.199  88.842  1.00 54.20  ? 22  ASN B CG  1 
ATOM 139  O OD1 . ASN A 1 22  ? 116.283 98.082  88.931  1.00 50.04  ? 22  ASN B OD1 1 
ATOM 140  N ND2 . ASN A 1 22  ? 118.050 99.383  88.456  1.00 54.01  ? 22  ASN B ND2 1 
ATOM 141  N N   . LEU A 1 23  ? 114.597 102.681 91.011  1.00 53.11  ? 23  LEU B N   1 
ATOM 142  C CA  . LEU A 1 23  ? 114.177 104.060 91.236  1.00 50.42  ? 23  LEU B CA  1 
ATOM 143  C C   . LEU A 1 23  ? 114.836 104.638 92.479  1.00 52.97  ? 23  LEU B C   1 
ATOM 144  O O   . LEU A 1 23  ? 115.248 105.802 92.485  1.00 52.33  ? 23  LEU B O   1 
ATOM 145  C CB  . LEU A 1 23  ? 112.656 104.138 91.356  1.00 46.62  ? 23  LEU B CB  1 
ATOM 146  C CG  . LEU A 1 23  ? 111.854 104.004 90.062  1.00 49.75  ? 23  LEU B CG  1 
ATOM 147  C CD1 . LEU A 1 23  ? 110.369 103.949 90.372  1.00 52.79  ? 23  LEU B CD1 1 
ATOM 148  C CD2 . LEU A 1 23  ? 112.158 105.147 89.111  1.00 50.33  ? 23  LEU B CD2 1 
ATOM 149  N N   . ARG A 1 24  ? 114.934 103.844 93.547  1.00 57.75  ? 24  ARG B N   1 
ATOM 150  C CA  . ARG A 1 24  ? 115.628 104.307 94.746  1.00 56.73  ? 24  ARG B CA  1 
ATOM 151  C C   . ARG A 1 24  ? 117.097 104.588 94.459  1.00 56.23  ? 24  ARG B C   1 
ATOM 152  O O   . ARG A 1 24  ? 117.649 105.590 94.929  1.00 58.91  ? 24  ARG B O   1 
ATOM 153  C CB  . ARG A 1 24  ? 115.491 103.275 95.861  1.00 58.74  ? 24  ARG B CB  1 
ATOM 154  C CG  . ARG A 1 24  ? 114.307 103.507 96.783  1.00 59.26  ? 24  ARG B CG  1 
ATOM 155  C CD  . ARG A 1 24  ? 113.805 102.203 97.382  1.00 58.67  ? 24  ARG B CD  1 
ATOM 156  N NE  . ARG A 1 24  ? 114.892 101.280 97.687  1.00 56.39  ? 24  ARG B NE  1 
ATOM 157  C CZ  . ARG A 1 24  ? 114.738 99.975  97.859  1.00 58.08  ? 24  ARG B CZ  1 
ATOM 158  N NH1 . ARG A 1 24  ? 113.549 99.400  97.777  1.00 57.24  ? 24  ARG B NH1 1 
ATOM 159  N NH2 . ARG A 1 24  ? 115.806 99.225  98.114  1.00 57.91  ? 24  ARG B NH2 1 
ATOM 160  N N   . GLU A 1 25  ? 117.750 103.710 93.694  1.00 59.45  ? 25  GLU B N   1 
ATOM 161  C CA  . GLU A 1 25  ? 119.146 103.947 93.338  1.00 61.92  ? 25  GLU B CA  1 
ATOM 162  C C   . GLU A 1 25  ? 119.301 105.242 92.552  1.00 67.03  ? 25  GLU B C   1 
ATOM 163  O O   . GLU A 1 25  ? 120.207 106.041 92.822  1.00 65.78  ? 25  GLU B O   1 
ATOM 164  C CB  . GLU A 1 25  ? 119.687 102.772 92.527  1.00 61.66  ? 25  GLU B CB  1 
ATOM 165  C CG  . GLU A 1 25  ? 119.798 101.472 93.301  1.00 66.06  ? 25  GLU B CG  1 
ATOM 166  C CD  . GLU A 1 25  ? 120.152 100.297 92.412  1.00 66.60  ? 25  GLU B CD  1 
ATOM 167  O OE1 . GLU A 1 25  ? 120.776 100.519 91.354  1.00 64.97  ? 25  GLU B OE1 1 
ATOM 168  O OE2 . GLU A 1 25  ? 119.800 99.153  92.768  1.00 63.58  ? 25  GLU B OE2 1 
ATOM 169  N N   . ASP A 1 26  ? 118.420 105.470 91.574  1.00 70.06  ? 26  ASP B N   1 
ATOM 170  C CA  . ASP A 1 26  ? 118.499 106.687 90.772  1.00 66.47  ? 26  ASP B CA  1 
ATOM 171  C C   . ASP A 1 26  ? 118.231 107.926 91.617  1.00 68.00  ? 26  ASP B C   1 
ATOM 172  O O   . ASP A 1 26  ? 118.875 108.963 91.429  1.00 67.33  ? 26  ASP B O   1 
ATOM 173  C CB  . ASP A 1 26  ? 117.515 106.608 89.609  1.00 66.75  ? 26  ASP B CB  1 
ATOM 174  C CG  . ASP A 1 26  ? 117.875 105.524 88.614  1.00 69.92  ? 26  ASP B CG  1 
ATOM 175  O OD1 . ASP A 1 26  ? 119.082 105.329 88.357  1.00 68.17  ? 26  ASP B OD1 1 
ATOM 176  O OD2 . ASP A 1 26  ? 116.953 104.864 88.091  1.00 70.37  ? 26  ASP B OD2 1 
ATOM 177  N N   . GLY A 1 27  ? 117.278 107.841 92.547  1.00 72.31  ? 27  GLY B N   1 
ATOM 178  C CA  . GLY A 1 27  ? 117.022 108.966 93.431  1.00 72.00  ? 27  GLY B CA  1 
ATOM 179  C C   . GLY A 1 27  ? 118.206 109.282 94.322  1.00 72.03  ? 27  GLY B C   1 
ATOM 180  O O   . GLY A 1 27  ? 118.543 110.451 94.530  1.00 73.28  ? 27  GLY B O   1 
ATOM 181  N N   . GLU A 1 28  ? 118.854 108.247 94.863  1.00 71.90  ? 28  GLU B N   1 
ATOM 182  C CA  . GLU A 1 28  ? 120.053 108.472 95.663  1.00 74.01  ? 28  GLU B CA  1 
ATOM 183  C C   . GLU A 1 28  ? 121.176 109.060 94.822  1.00 74.03  ? 28  GLU B C   1 
ATOM 184  O O   . GLU A 1 28  ? 121.964 109.870 95.322  1.00 76.31  ? 28  GLU B O   1 
ATOM 185  C CB  . GLU A 1 28  ? 120.510 107.167 96.311  1.00 75.08  ? 28  GLU B CB  1 
ATOM 186  C CG  . GLU A 1 28  ? 119.564 106.633 97.371  1.00 75.37  ? 28  GLU B CG  1 
ATOM 187  C CD  . GLU A 1 28  ? 119.893 105.214 97.786  1.00 74.71  ? 28  GLU B CD  1 
ATOM 188  O OE1 . GLU A 1 28  ? 120.993 104.732 97.446  1.00 72.89  ? 28  GLU B OE1 1 
ATOM 189  O OE2 . GLU A 1 28  ? 119.048 104.578 98.449  1.00 74.16  ? 28  GLU B OE2 1 
ATOM 190  N N   . LYS A 1 29  ? 121.267 108.670 93.549  1.00 73.34  ? 29  LYS B N   1 
ATOM 191  C CA  . LYS A 1 29  ? 122.282 109.251 92.677  1.00 75.13  ? 29  LYS B CA  1 
ATOM 192  C C   . LYS A 1 29  ? 122.050 110.744 92.482  1.00 76.48  ? 29  LYS B C   1 
ATOM 193  O O   . LYS A 1 29  ? 123.006 111.527 92.431  1.00 76.63  ? 29  LYS B O   1 
ATOM 194  C CB  . LYS A 1 29  ? 122.289 108.527 91.330  1.00 76.45  ? 29  LYS B CB  1 
ATOM 195  C CG  . LYS A 1 29  ? 123.161 109.173 90.256  1.00 76.27  ? 29  LYS B CG  1 
ATOM 196  C CD  . LYS A 1 29  ? 124.622 109.265 90.675  1.00 77.11  ? 29  LYS B CD  1 
ATOM 197  C CE  . LYS A 1 29  ? 125.416 110.149 89.728  1.00 77.37  ? 29  LYS B CE  1 
ATOM 198  N NZ  . LYS A 1 29  ? 124.992 111.575 89.813  1.00 77.11  ? 29  LYS B NZ  1 
ATOM 199  N N   . ALA A 1 30  ? 120.789 111.157 92.371  1.00 82.45  ? 30  ALA B N   1 
ATOM 200  C CA  . ALA A 1 30  ? 120.444 112.550 92.117  1.00 82.31  ? 30  ALA B CA  1 
ATOM 201  C C   . ALA A 1 30  ? 120.426 113.403 93.378  1.00 81.36  ? 30  ALA B C   1 
ATOM 202  O O   . ALA A 1 30  ? 120.165 114.607 93.284  1.00 78.96  ? 30  ALA B O   1 
ATOM 203  C CB  . ALA A 1 30  ? 119.080 112.632 91.429  1.00 80.33  ? 30  ALA B CB  1 
ATOM 204  N N   . ALA A 1 31  ? 120.689 112.818 94.548  1.00 86.46  ? 31  ALA B N   1 
ATOM 205  C CA  . ALA A 1 31  ? 120.715 113.583 95.788  1.00 86.67  ? 31  ALA B CA  1 
ATOM 206  C C   . ALA A 1 31  ? 121.929 114.496 95.893  1.00 87.94  ? 31  ALA B C   1 
ATOM 207  O O   . ALA A 1 31  ? 121.984 115.318 96.814  1.00 86.16  ? 31  ALA B O   1 
ATOM 208  C CB  . ALA A 1 31  ? 120.679 112.635 96.987  1.00 84.39  ? 31  ALA B CB  1 
ATOM 209  N N   . ARG A 1 32  ? 122.898 114.369 94.986  1.00 95.81  ? 32  ARG B N   1 
ATOM 210  C CA  . ARG A 1 32  ? 124.078 115.222 94.954  1.00 95.93  ? 32  ARG B CA  1 
ATOM 211  C C   . ARG A 1 32  ? 124.002 116.269 93.846  1.00 96.19  ? 32  ARG B C   1 
ATOM 212  O O   . ARG A 1 32  ? 125.042 116.751 93.384  1.00 96.91  ? 32  ARG B O   1 
ATOM 213  C CB  . ARG A 1 32  ? 125.335 114.367 94.790  1.00 94.68  ? 32  ARG B CB  1 
ATOM 214  C CG  . ARG A 1 32  ? 125.576 113.396 95.938  1.00 95.07  ? 32  ARG B CG  1 
ATOM 215  C CD  . ARG A 1 32  ? 126.691 112.407 95.626  1.00 96.30  ? 32  ARG B CD  1 
ATOM 216  N NE  . ARG A 1 32  ? 127.940 113.072 95.278  1.00 95.91  ? 32  ARG B NE  1 
ATOM 217  C CZ  . ARG A 1 32  ? 129.088 112.448 95.052  1.00 95.21  ? 32  ARG B CZ  1 
ATOM 218  N NH1 . ARG A 1 32  ? 129.191 111.131 95.138  1.00 94.20  ? 32  ARG B NH1 1 
ATOM 219  N NH2 . ARG A 1 32  ? 130.163 113.164 94.733  1.00 96.15  ? 32  ARG B NH2 1 
ATOM 220  N N   . GLU A 1 33  ? 122.795 116.619 93.407  1.00 93.86  ? 33  GLU B N   1 
ATOM 221  C CA  . GLU A 1 33  ? 122.579 117.576 92.331  1.00 92.89  ? 33  GLU B CA  1 
ATOM 222  C C   . GLU A 1 33  ? 121.870 118.813 92.869  1.00 94.18  ? 33  GLU B C   1 
ATOM 223  O O   . GLU A 1 33  ? 120.988 118.711 93.727  1.00 94.09  ? 33  GLU B O   1 
ATOM 224  C CB  . GLU A 1 33  ? 121.758 116.948 91.201  1.00 93.31  ? 33  GLU B CB  1 
ATOM 225  C CG  . GLU A 1 33  ? 122.486 115.849 90.432  1.00 95.41  ? 33  GLU B CG  1 
ATOM 226  C CD  . GLU A 1 33  ? 123.714 116.355 89.704  1.00 95.80  ? 33  GLU B CD  1 
ATOM 227  O OE1 . GLU A 1 33  ? 123.796 117.574 89.460  1.00 95.56  ? 33  GLU B OE1 1 
ATOM 228  O OE2 . GLU A 1 33  ? 124.597 115.535 89.376  1.00 94.51  ? 33  GLU B OE2 1 
ATOM 229  N N   . VAL A 1 34  ? 122.263 119.979 92.360  1.00 88.15  ? 34  VAL B N   1 
ATOM 230  C CA  . VAL A 1 34  ? 121.756 121.268 92.819  1.00 87.15  ? 34  VAL B CA  1 
ATOM 231  C C   . VAL A 1 34  ? 121.353 122.086 91.601  1.00 86.40  ? 34  VAL B C   1 
ATOM 232  O O   . VAL A 1 34  ? 122.083 122.124 90.605  1.00 86.93  ? 34  VAL B O   1 
ATOM 233  C CB  . VAL A 1 34  ? 122.805 122.016 93.663  1.00 87.86  ? 34  VAL B CB  1 
ATOM 234  C CG1 . VAL A 1 34  ? 122.461 123.501 93.818  1.00 87.42  ? 34  VAL B CG1 1 
ATOM 235  C CG2 . VAL A 1 34  ? 122.919 121.371 95.027  1.00 86.78  ? 34  VAL B CG2 1 
ATOM 236  N N   . LYS A 1 35  ? 120.196 122.741 91.684  1.00 80.55  ? 35  LYS B N   1 
ATOM 237  C CA  . LYS A 1 35  ? 119.694 123.607 90.618  1.00 81.01  ? 35  LYS B CA  1 
ATOM 238  C C   . LYS A 1 35  ? 119.773 125.056 91.088  1.00 77.99  ? 35  LYS B C   1 
ATOM 239  O O   . LYS A 1 35  ? 118.911 125.529 91.831  1.00 76.67  ? 35  LYS B O   1 
ATOM 240  C CB  . LYS A 1 35  ? 118.276 123.205 90.232  1.00 78.26  ? 35  LYS B CB  1 
ATOM 241  C CG  . LYS A 1 35  ? 118.256 121.884 89.497  1.00 79.45  ? 35  LYS B CG  1 
ATOM 242  C CD  . LYS A 1 35  ? 116.886 121.478 89.012  1.00 79.51  ? 35  LYS B CD  1 
ATOM 243  C CE  . LYS A 1 35  ? 116.970 120.110 88.349  1.00 79.35  ? 35  LYS B CE  1 
ATOM 244  N NZ  . LYS A 1 35  ? 115.718 119.691 87.661  1.00 78.79  ? 35  LYS B NZ  1 
ATOM 245  N N   . LEU A 1 36  ? 120.817 125.756 90.649  1.00 72.97  ? 36  LEU B N   1 
ATOM 246  C CA  . LEU A 1 36  ? 121.044 127.153 91.015  1.00 71.42  ? 36  LEU B CA  1 
ATOM 247  C C   . LEU A 1 36  ? 120.270 128.040 90.051  1.00 73.07  ? 36  LEU B C   1 
ATOM 248  O O   . LEU A 1 36  ? 120.795 128.493 89.036  1.00 75.54  ? 36  LEU B O   1 
ATOM 249  C CB  . LEU A 1 36  ? 122.530 127.489 90.976  1.00 72.63  ? 36  LEU B CB  1 
ATOM 250  C CG  . LEU A 1 36  ? 123.519 126.649 91.782  1.00 73.12  ? 36  LEU B CG  1 
ATOM 251  C CD1 . LEU A 1 36  ? 124.917 127.199 91.566  1.00 73.77  ? 36  LEU B CD1 1 
ATOM 252  C CD2 . LEU A 1 36  ? 123.167 126.620 93.260  1.00 73.77  ? 36  LEU B CD2 1 
ATOM 253  N N   . LEU A 1 37  ? 119.011 128.315 90.375  1.00 73.96  ? 37  LEU B N   1 
ATOM 254  C CA  . LEU A 1 37  ? 118.222 129.206 89.538  1.00 73.29  ? 37  LEU B CA  1 
ATOM 255  C C   . LEU A 1 37  ? 118.877 130.577 89.475  1.00 74.70  ? 37  LEU B C   1 
ATOM 256  O O   . LEU A 1 37  ? 119.202 131.170 90.506  1.00 74.95  ? 37  LEU B O   1 
ATOM 257  C CB  . LEU A 1 37  ? 116.803 129.331 90.087  1.00 72.79  ? 37  LEU B CB  1 
ATOM 258  C CG  . LEU A 1 37  ? 115.853 130.242 89.306  1.00 75.50  ? 37  LEU B CG  1 
ATOM 259  C CD1 . LEU A 1 37  ? 115.678 129.742 87.884  1.00 75.04  ? 37  LEU B CD1 1 
ATOM 260  C CD2 . LEU A 1 37  ? 114.509 130.344 90.013  1.00 76.12  ? 37  LEU B CD2 1 
ATOM 261  N N   . LEU A 1 38  ? 119.063 131.082 88.259  1.00 78.73  ? 38  LEU B N   1 
ATOM 262  C CA  . LEU A 1 38  ? 119.638 132.402 88.031  1.00 80.10  ? 38  LEU B CA  1 
ATOM 263  C C   . LEU A 1 38  ? 118.586 133.275 87.366  1.00 81.96  ? 38  LEU B C   1 
ATOM 264  O O   . LEU A 1 38  ? 118.036 132.904 86.324  1.00 82.69  ? 38  LEU B O   1 
ATOM 265  C CB  . LEU A 1 38  ? 120.899 132.319 87.170  1.00 81.01  ? 38  LEU B CB  1 
ATOM 266  C CG  . LEU A 1 38  ? 121.408 133.644 86.600  1.00 81.59  ? 38  LEU B CG  1 
ATOM 267  C CD1 . LEU A 1 38  ? 121.726 134.632 87.710  1.00 79.47  ? 38  LEU B CD1 1 
ATOM 268  C CD2 . LEU A 1 38  ? 122.626 133.406 85.726  1.00 80.43  ? 38  LEU B CD2 1 
ATOM 269  N N   . LEU A 1 39  ? 118.311 134.428 87.965  1.00 85.17  ? 39  LEU B N   1 
ATOM 270  C CA  . LEU A 1 39  ? 117.273 135.314 87.464  1.00 84.01  ? 39  LEU B CA  1 
ATOM 271  C C   . LEU A 1 39  ? 117.505 136.746 87.928  1.00 82.51  ? 39  LEU B C   1 
ATOM 272  O O   . LEU A 1 39  ? 118.390 137.435 87.421  1.00 83.36  ? 39  LEU B O   1 
ATOM 273  C CB  . LEU A 1 39  ? 115.898 134.821 87.920  1.00 83.33  ? 39  LEU B CB  1 
ATOM 274  C CG  . LEU A 1 39  ? 114.690 135.709 87.626  1.00 83.30  ? 39  LEU B CG  1 
ATOM 275  C CD1 . LEU A 1 39  ? 114.657 136.130 86.165  1.00 82.70  ? 39  LEU B CD1 1 
ATOM 276  C CD2 . LEU A 1 39  ? 113.406 134.981 88.006  1.00 82.44  ? 39  LEU B CD2 1 
ATOM 277  N N   . ILE A 1 184 ? 117.113 127.735 77.478  1.00 84.76  ? 184 ILE B N   1 
ATOM 278  C CA  . ILE A 1 184 ? 117.877 128.934 77.805  1.00 84.86  ? 184 ILE B CA  1 
ATOM 279  C C   . ILE A 1 184 ? 119.292 128.545 78.224  1.00 85.17  ? 184 ILE B C   1 
ATOM 280  O O   . ILE A 1 184 ? 119.592 127.362 78.386  1.00 84.89  ? 184 ILE B O   1 
ATOM 281  C CB  . ILE A 1 184 ? 117.178 129.767 78.906  1.00 85.61  ? 184 ILE B CB  1 
ATOM 282  C CG1 . ILE A 1 184 ? 116.720 128.898 80.084  1.00 84.87  ? 184 ILE B CG1 1 
ATOM 283  C CG2 . ILE A 1 184 ? 115.965 130.490 78.335  1.00 85.16  ? 184 ILE B CG2 1 
ATOM 284  C CD1 . ILE A 1 184 ? 117.827 128.365 80.970  1.00 84.81  ? 184 ILE B CD1 1 
ATOM 285  N N   . VAL A 1 185 ? 120.159 129.544 78.389  1.00 87.37  ? 185 VAL B N   1 
ATOM 286  C CA  . VAL A 1 185 ? 121.543 129.316 78.793  1.00 87.97  ? 185 VAL B CA  1 
ATOM 287  C C   . VAL A 1 185 ? 121.558 128.468 80.058  1.00 88.01  ? 185 VAL B C   1 
ATOM 288  O O   . VAL A 1 185 ? 120.912 128.807 81.056  1.00 87.78  ? 185 VAL B O   1 
ATOM 289  C CB  . VAL A 1 185 ? 122.293 130.647 79.001  1.00 88.78  ? 185 VAL B CB  1 
ATOM 290  C CG1 . VAL A 1 185 ? 123.730 130.399 79.438  1.00 87.87  ? 185 VAL B CG1 1 
ATOM 291  C CG2 . VAL A 1 185 ? 122.268 131.483 77.726  1.00 87.16  ? 185 VAL B CG2 1 
ATOM 292  N N   . GLU A 1 186 ? 122.295 127.359 80.022  1.00 90.60  ? 186 GLU B N   1 
ATOM 293  C CA  . GLU A 1 186 ? 122.401 126.438 81.148  1.00 89.17  ? 186 GLU B CA  1 
ATOM 294  C C   . GLU A 1 186 ? 123.871 126.148 81.404  1.00 91.97  ? 186 GLU B C   1 
ATOM 295  O O   . GLU A 1 186 ? 124.566 125.630 80.523  1.00 93.17  ? 186 GLU B O   1 
ATOM 296  C CB  . GLU A 1 186 ? 121.631 125.146 80.864  1.00 89.18  ? 186 GLU B CB  1 
ATOM 297  C CG  . GLU A 1 186 ? 121.680 124.119 81.979  1.00 89.89  ? 186 GLU B CG  1 
ATOM 298  C CD  . GLU A 1 186 ? 120.926 122.853 81.628  1.00 90.72  ? 186 GLU B CD  1 
ATOM 299  O OE1 . GLU A 1 186 ? 120.232 122.845 80.590  1.00 90.34  ? 186 GLU B OE1 1 
ATOM 300  O OE2 . GLU A 1 186 ? 121.028 121.868 82.389  1.00 90.56  ? 186 GLU B OE2 1 
ATOM 301  N N   . THR A 1 187 ? 124.341 126.480 82.603  1.00 93.00  ? 187 THR B N   1 
ATOM 302  C CA  . THR A 1 187 ? 125.723 126.255 83.010  1.00 92.61  ? 187 THR B CA  1 
ATOM 303  C C   . THR A 1 187 ? 125.750 125.165 84.074  1.00 92.09  ? 187 THR B C   1 
ATOM 304  O O   . THR A 1 187 ? 125.180 125.337 85.156  1.00 93.62  ? 187 THR B O   1 
ATOM 305  C CB  . THR A 1 187 ? 126.349 127.544 83.546  1.00 92.39  ? 187 THR B CB  1 
ATOM 306  O OG1 . THR A 1 187 ? 126.318 128.554 82.530  1.00 92.61  ? 187 THR B OG1 1 
ATOM 307  C CG2 . THR A 1 187 ? 127.788 127.310 83.982  1.00 92.83  ? 187 THR B CG2 1 
ATOM 308  N N   . HIS A 1 188 ? 126.412 124.052 83.765  1.00 93.50  ? 188 HIS B N   1 
ATOM 309  C CA  . HIS A 1 188 ? 126.603 122.953 84.702  1.00 94.45  ? 188 HIS B CA  1 
ATOM 310  C C   . HIS A 1 188 ? 128.068 122.904 85.112  1.00 95.86  ? 188 HIS B C   1 
ATOM 311  O O   . HIS A 1 188 ? 128.955 122.887 84.252  1.00 95.86  ? 188 HIS B O   1 
ATOM 312  C CB  . HIS A 1 188 ? 126.176 121.620 84.078  1.00 94.12  ? 188 HIS B CB  1 
ATOM 313  C CG  . HIS A 1 188 ? 126.304 120.445 85.000  1.00 95.77  ? 188 HIS B CG  1 
ATOM 314  N ND1 . HIS A 1 188 ? 127.508 119.823 85.252  1.00 95.65  ? 188 HIS B ND1 1 
ATOM 315  C CD2 . HIS A 1 188 ? 125.375 119.770 85.718  1.00 95.70  ? 188 HIS B CD2 1 
ATOM 316  C CE1 . HIS A 1 188 ? 127.316 118.821 86.091  1.00 95.17  ? 188 HIS B CE1 1 
ATOM 317  N NE2 . HIS A 1 188 ? 126.031 118.767 86.389  1.00 95.30  ? 188 HIS B NE2 1 
ATOM 318  N N   . PHE A 1 189 ? 128.321 122.890 86.419  1.00 95.05  ? 189 PHE B N   1 
ATOM 319  C CA  . PHE A 1 189 ? 129.683 122.866 86.933  1.00 94.24  ? 189 PHE B CA  1 
ATOM 320  C C   . PHE A 1 189 ? 129.700 122.139 88.269  1.00 94.48  ? 189 PHE B C   1 
ATOM 321  O O   . PHE A 1 189 ? 128.781 122.294 89.078  1.00 94.69  ? 189 PHE B O   1 
ATOM 322  C CB  . PHE A 1 189 ? 130.252 124.284 87.085  1.00 94.92  ? 189 PHE B CB  1 
ATOM 323  C CG  . PHE A 1 189 ? 129.474 125.161 88.026  1.00 94.48  ? 189 PHE B CG  1 
ATOM 324  C CD1 . PHE A 1 189 ? 128.280 125.742 87.630  1.00 94.51  ? 189 PHE B CD1 1 
ATOM 325  C CD2 . PHE A 1 189 ? 129.948 125.421 89.302  1.00 94.73  ? 189 PHE B CD2 1 
ATOM 326  C CE1 . PHE A 1 189 ? 127.567 126.555 88.493  1.00 94.64  ? 189 PHE B CE1 1 
ATOM 327  C CE2 . PHE A 1 189 ? 129.240 126.234 90.168  1.00 94.62  ? 189 PHE B CE2 1 
ATOM 328  C CZ  . PHE A 1 189 ? 128.049 126.801 89.763  1.00 94.50  ? 189 PHE B CZ  1 
ATOM 329  N N   . THR A 1 190 ? 130.739 121.336 88.484  1.00 98.40  ? 190 THR B N   1 
ATOM 330  C CA  . THR A 1 190 ? 130.918 120.590 89.721  1.00 98.65  ? 190 THR B CA  1 
ATOM 331  C C   . THR A 1 190 ? 131.993 121.241 90.583  1.00 99.33  ? 190 THR B C   1 
ATOM 332  O O   . THR A 1 190 ? 132.902 121.905 90.079  1.00 98.68  ? 190 THR B O   1 
ATOM 333  C CB  . THR A 1 190 ? 131.291 119.132 89.441  1.00 98.28  ? 190 THR B CB  1 
ATOM 334  O OG1 . THR A 1 190 ? 131.315 118.398 90.671  1.00 98.03  ? 190 THR B OG1 1 
ATOM 335  C CG2 . THR A 1 190 ? 132.658 119.032 88.768  1.00 97.85  ? 190 THR B CG2 1 
ATOM 336  N N   . PHE A 1 191 ? 131.881 121.039 91.894  1.00 103.26 ? 191 PHE B N   1 
ATOM 337  C CA  . PHE A 1 191 ? 132.826 121.625 92.840  1.00 102.71 ? 191 PHE B CA  1 
ATOM 338  C C   . PHE A 1 191 ? 132.683 120.905 94.170  1.00 101.40 ? 191 PHE B C   1 
ATOM 339  O O   . PHE A 1 191 ? 131.586 120.867 94.736  1.00 102.47 ? 191 PHE B O   1 
ATOM 340  C CB  . PHE A 1 191 ? 132.569 123.128 92.991  1.00 102.90 ? 191 PHE B CB  1 
ATOM 341  C CG  . PHE A 1 191 ? 133.385 123.789 94.068  1.00 103.32 ? 191 PHE B CG  1 
ATOM 342  C CD1 . PHE A 1 191 ? 132.921 123.848 95.372  1.00 103.45 ? 191 PHE B CD1 1 
ATOM 343  C CD2 . PHE A 1 191 ? 134.607 124.370 93.772  1.00 102.97 ? 191 PHE B CD2 1 
ATOM 344  C CE1 . PHE A 1 191 ? 133.666 124.462 96.363  1.00 103.60 ? 191 PHE B CE1 1 
ATOM 345  C CE2 . PHE A 1 191 ? 135.356 124.985 94.759  1.00 103.26 ? 191 PHE B CE2 1 
ATOM 346  C CZ  . PHE A 1 191 ? 134.883 125.031 96.055  1.00 104.14 ? 191 PHE B CZ  1 
ATOM 347  N N   . LYS A 1 192 ? 133.784 120.342 94.665  1.00 100.64 ? 192 LYS B N   1 
ATOM 348  C CA  . LYS A 1 192 ? 133.823 119.634 95.945  1.00 102.27 ? 192 LYS B CA  1 
ATOM 349  C C   . LYS A 1 192 ? 132.717 118.580 96.033  1.00 102.25 ? 192 LYS B C   1 
ATOM 350  O O   . LYS A 1 192 ? 131.827 118.633 96.883  1.00 102.70 ? 192 LYS B O   1 
ATOM 351  C CB  . LYS A 1 192 ? 133.737 120.623 97.110  1.00 102.54 ? 192 LYS B CB  1 
ATOM 352  C CG  . LYS A 1 192 ? 135.085 121.045 97.674  1.00 102.28 ? 192 LYS B CG  1 
ATOM 353  C CD  . LYS A 1 192 ? 136.010 121.592 96.602  1.00 103.10 ? 192 LYS B CD  1 
ATOM 354  C CE  . LYS A 1 192 ? 137.299 122.121 97.207  1.00 102.77 ? 192 LYS B CE  1 
ATOM 355  N NZ  . LYS A 1 192 ? 138.197 122.721 96.183  1.00 101.96 ? 192 LYS B NZ  1 
ATOM 356  N N   . ASP A 1 193 ? 132.795 117.604 95.130  1.00 102.41 ? 193 ASP B N   1 
ATOM 357  C CA  . ASP A 1 193 ? 131.888 116.456 95.145  1.00 102.97 ? 193 ASP B CA  1 
ATOM 358  C C   . ASP A 1 193 ? 130.427 116.900 95.138  1.00 103.81 ? 193 ASP B C   1 
ATOM 359  O O   . ASP A 1 193 ? 129.585 116.334 95.839  1.00 102.72 ? 193 ASP B O   1 
ATOM 360  C CB  . ASP A 1 193 ? 132.166 115.558 96.353  1.00 103.03 ? 193 ASP B CB  1 
ATOM 361  C CG  . ASP A 1 193 ? 133.474 114.800 96.231  1.00 103.82 ? 193 ASP B CG  1 
ATOM 362  O OD1 . ASP A 1 193 ? 134.027 114.739 95.113  1.00 103.72 ? 193 ASP B OD1 1 
ATOM 363  O OD2 . ASP A 1 193 ? 133.947 114.265 97.257  1.00 102.74 ? 193 ASP B OD2 1 
ATOM 364  N N   . LEU A 1 194 ? 130.121 117.925 94.345  1.00 98.40  ? 194 LEU B N   1 
ATOM 365  C CA  . LEU A 1 194 ? 128.762 118.449 94.270  1.00 96.94  ? 194 LEU B CA  1 
ATOM 366  C C   . LEU A 1 194 ? 128.589 119.157 92.937  1.00 96.36  ? 194 LEU B C   1 
ATOM 367  O O   . LEU A 1 194 ? 129.444 119.955 92.544  1.00 96.66  ? 194 LEU B O   1 
ATOM 368  C CB  . LEU A 1 194 ? 128.475 119.408 95.434  1.00 96.96  ? 194 LEU B CB  1 
ATOM 369  C CG  . LEU A 1 194 ? 127.120 120.120 95.445  1.00 96.13  ? 194 LEU B CG  1 
ATOM 370  C CD1 . LEU A 1 194 ? 125.975 119.132 95.326  1.00 97.27  ? 194 LEU B CD1 1 
ATOM 371  C CD2 . LEU A 1 194 ? 126.970 120.959 96.704  1.00 94.85  ? 194 LEU B CD2 1 
ATOM 372  N N   . HIS A 1 195 ? 127.497 118.855 92.243  1.00 96.95  ? 195 HIS B N   1 
ATOM 373  C CA  . HIS A 1 195 ? 127.208 119.463 90.955  1.00 97.54  ? 195 HIS B CA  1 
ATOM 374  C C   . HIS A 1 195 ? 126.253 120.642 91.113  1.00 97.85  ? 195 HIS B C   1 
ATOM 375  O O   . HIS A 1 195 ? 125.483 120.728 92.072  1.00 98.32  ? 195 HIS B O   1 
ATOM 376  C CB  . HIS A 1 195 ? 126.606 118.434 90.004  1.00 98.09  ? 195 HIS B CB  1 
ATOM 377  C CG  . HIS A 1 195 ? 127.499 117.265 89.735  1.00 100.18 ? 195 HIS B CG  1 
ATOM 378  N ND1 . HIS A 1 195 ? 128.429 117.256 88.717  1.00 99.12  ? 195 HIS B ND1 1 
ATOM 379  C CD2 . HIS A 1 195 ? 127.606 116.066 90.353  1.00 98.92  ? 195 HIS B CD2 1 
ATOM 380  C CE1 . HIS A 1 195 ? 129.069 116.101 88.721  1.00 98.72  ? 195 HIS B CE1 1 
ATOM 381  N NE2 . HIS A 1 195 ? 128.589 115.360 89.703  1.00 97.58  ? 195 HIS B NE2 1 
ATOM 382  N N   . PHE A 1 196 ? 126.313 121.556 90.149  1.00 91.59  ? 196 PHE B N   1 
ATOM 383  C CA  . PHE A 1 196 ? 125.470 122.743 90.138  1.00 90.81  ? 196 PHE B CA  1 
ATOM 384  C C   . PHE A 1 196 ? 124.939 122.959 88.729  1.00 91.57  ? 196 PHE B C   1 
ATOM 385  O O   . PHE A 1 196 ? 125.695 122.866 87.758  1.00 91.55  ? 196 PHE B O   1 
ATOM 386  C CB  . PHE A 1 196 ? 126.246 123.976 90.610  1.00 90.34  ? 196 PHE B CB  1 
ATOM 387  C CG  . PHE A 1 196 ? 126.935 123.792 91.933  1.00 90.09  ? 196 PHE B CG  1 
ATOM 388  C CD1 . PHE A 1 196 ? 128.155 123.142 92.013  1.00 90.78  ? 196 PHE B CD1 1 
ATOM 389  C CD2 . PHE A 1 196 ? 126.369 124.280 93.096  1.00 89.47  ? 196 PHE B CD2 1 
ATOM 390  C CE1 . PHE A 1 196 ? 128.788 122.976 93.227  1.00 90.22  ? 196 PHE B CE1 1 
ATOM 391  C CE2 . PHE A 1 196 ? 127.003 124.116 94.308  1.00 90.89  ? 196 PHE B CE2 1 
ATOM 392  C CZ  . PHE A 1 196 ? 128.212 123.464 94.372  1.00 90.83  ? 196 PHE B CZ  1 
ATOM 393  N N   . LYS A 1 197 ? 123.641 123.239 88.623  1.00 84.85  ? 197 LYS B N   1 
ATOM 394  C CA  . LYS A 1 197 ? 122.963 123.477 87.349  1.00 81.91  ? 197 LYS B CA  1 
ATOM 395  C C   . LYS A 1 197 ? 122.396 124.891 87.381  1.00 81.66  ? 197 LYS B C   1 
ATOM 396  O O   . LYS A 1 197 ? 121.379 125.141 88.034  1.00 84.31  ? 197 LYS B O   1 
ATOM 397  C CB  . LYS A 1 197 ? 121.857 122.453 87.116  1.00 82.10  ? 197 LYS B CB  1 
ATOM 398  C CG  . LYS A 1 197 ? 122.248 121.020 87.409  1.00 81.99  ? 197 LYS B CG  1 
ATOM 399  C CD  . LYS A 1 197 ? 121.026 120.127 87.454  1.00 82.72  ? 197 LYS B CD  1 
ATOM 400  C CE  . LYS A 1 197 ? 121.396 118.694 87.773  1.00 84.03  ? 197 LYS B CE  1 
ATOM 401  N NZ  . LYS A 1 197 ? 120.211 117.857 88.114  1.00 84.98  ? 197 LYS B NZ  1 
ATOM 402  N N   . MET A 1 198 ? 123.050 125.813 86.684  1.00 79.71  ? 198 MET B N   1 
ATOM 403  C CA  . MET A 1 198 ? 122.624 127.206 86.671  1.00 81.23  ? 198 MET B CA  1 
ATOM 404  C C   . MET A 1 198 ? 121.787 127.476 85.429  1.00 82.91  ? 198 MET B C   1 
ATOM 405  O O   . MET A 1 198 ? 122.210 127.169 84.311  1.00 84.74  ? 198 MET B O   1 
ATOM 406  C CB  . MET A 1 198 ? 123.833 128.139 86.710  1.00 81.51  ? 198 MET B CB  1 
ATOM 407  C CG  . MET A 1 198 ? 123.481 129.596 86.957  1.00 83.37  ? 198 MET B CG  1 
ATOM 408  S SD  . MET A 1 198 ? 124.925 130.671 87.045  1.00 87.59  ? 198 MET B SD  1 
ATOM 409  C CE  . MET A 1 198 ? 125.652 130.140 88.593  1.00 82.65  ? 198 MET B CE  1 
ATOM 410  N N   . PHE A 1 199 ? 120.604 128.055 85.627  1.00 75.42  ? 199 PHE B N   1 
ATOM 411  C CA  . PHE A 1 199 ? 119.676 128.354 84.544  1.00 75.27  ? 199 PHE B CA  1 
ATOM 412  C C   . PHE A 1 199 ? 119.464 129.858 84.459  1.00 77.18  ? 199 PHE B C   1 
ATOM 413  O O   . PHE A 1 199 ? 119.031 130.483 85.433  1.00 74.60  ? 199 PHE B O   1 
ATOM 414  C CB  . PHE A 1 199 ? 118.336 127.647 84.757  1.00 74.05  ? 199 PHE B CB  1 
ATOM 415  C CG  . PHE A 1 199 ? 118.461 126.175 85.001  1.00 73.44  ? 199 PHE B CG  1 
ATOM 416  C CD1 . PHE A 1 199 ? 118.568 125.292 83.943  1.00 74.98  ? 199 PHE B CD1 1 
ATOM 417  C CD2 . PHE A 1 199 ? 118.469 125.671 86.290  1.00 73.82  ? 199 PHE B CD2 1 
ATOM 418  C CE1 . PHE A 1 199 ? 118.684 123.934 84.166  1.00 75.46  ? 199 PHE B CE1 1 
ATOM 419  C CE2 . PHE A 1 199 ? 118.583 124.315 86.518  1.00 74.39  ? 199 PHE B CE2 1 
ATOM 420  C CZ  . PHE A 1 199 ? 118.691 123.447 85.455  1.00 74.18  ? 199 PHE B CZ  1 
ATOM 421  N N   . ASP A 1 200 ? 119.739 130.428 83.288  1.00 84.96  ? 200 ASP B N   1 
ATOM 422  C CA  . ASP A 1 200 ? 119.615 131.862 83.056  1.00 84.62  ? 200 ASP B CA  1 
ATOM 423  C C   . ASP A 1 200 ? 118.272 132.146 82.397  1.00 85.31  ? 200 ASP B C   1 
ATOM 424  O O   . ASP A 1 200 ? 117.957 131.573 81.349  1.00 84.91  ? 200 ASP B O   1 
ATOM 425  C CB  . ASP A 1 200 ? 120.754 132.375 82.178  1.00 83.99  ? 200 ASP B CB  1 
ATOM 426  C CG  . ASP A 1 200 ? 120.776 133.888 82.073  1.00 88.45  ? 200 ASP B CG  1 
ATOM 427  O OD1 . ASP A 1 200 ? 120.000 134.550 82.795  1.00 87.76  ? 200 ASP B OD1 1 
ATOM 428  O OD2 . ASP A 1 200 ? 121.568 134.415 81.265  1.00 88.44  ? 200 ASP B OD2 1 
ATOM 429  N N   . VAL A 1 201 ? 117.490 133.027 83.009  1.00 86.20  ? 201 VAL B N   1 
ATOM 430  C CA  . VAL A 1 201 ? 116.187 133.403 82.477  1.00 85.50  ? 201 VAL B CA  1 
ATOM 431  C C   . VAL A 1 201 ? 115.803 134.774 83.016  1.00 86.56  ? 201 VAL B C   1 
ATOM 432  O O   . VAL A 1 201 ? 116.079 135.797 82.390  1.00 86.36  ? 201 VAL B O   1 
ATOM 433  C CB  . VAL A 1 201 ? 115.115 132.352 82.826  1.00 87.26  ? 201 VAL B CB  1 
ATOM 434  C CG1 . VAL A 1 201 ? 114.928 132.259 84.338  1.00 85.76  ? 201 VAL B CG1 1 
ATOM 435  C CG2 . VAL A 1 201 ? 113.796 132.672 82.122  1.00 85.86  ? 201 VAL B CG2 1 
ATOM 436  N N   . SER A 1 206 ? 110.080 136.416 81.329  1.00 81.14  ? 206 SER B N   1 
ATOM 437  C CA  . SER A 1 206 ? 109.512 137.748 81.157  1.00 83.39  ? 206 SER B CA  1 
ATOM 438  C C   . SER A 1 206 ? 108.174 137.891 81.881  1.00 83.81  ? 206 SER B C   1 
ATOM 439  O O   . SER A 1 206 ? 107.594 138.975 81.914  1.00 83.05  ? 206 SER B O   1 
ATOM 440  C CB  . SER A 1 206 ? 109.333 138.060 79.671  1.00 82.63  ? 206 SER B CB  1 
ATOM 441  O OG  . SER A 1 206 ? 110.573 138.018 78.989  1.00 82.73  ? 206 SER B OG  1 
ATOM 442  N N   . GLU A 1 207 ? 107.689 136.795 82.462  1.00 77.90  ? 207 GLU B N   1 
ATOM 443  C CA  . GLU A 1 207 ? 106.416 136.782 83.164  1.00 76.04  ? 207 GLU B CA  1 
ATOM 444  C C   . GLU A 1 207 ? 106.608 136.195 84.553  1.00 75.91  ? 207 GLU B C   1 
ATOM 445  O O   . GLU A 1 207 ? 107.494 135.368 84.780  1.00 75.10  ? 207 GLU B O   1 
ATOM 446  C CB  . GLU A 1 207 ? 105.361 135.968 82.405  1.00 78.00  ? 207 GLU B CB  1 
ATOM 447  C CG  . GLU A 1 207 ? 105.328 136.218 80.906  1.00 78.28  ? 207 GLU B CG  1 
ATOM 448  C CD  . GLU A 1 207 ? 104.254 135.414 80.199  1.00 78.19  ? 207 GLU B CD  1 
ATOM 449  O OE1 . GLU A 1 207 ? 103.373 134.856 80.888  1.00 75.96  ? 207 GLU B OE1 1 
ATOM 450  O OE2 . GLU A 1 207 ? 104.290 135.340 78.954  1.00 75.77  ? 207 GLU B OE2 1 
ATOM 451  N N   . ARG A 1 208 ? 105.769 136.644 85.487  1.00 77.89  ? 208 ARG B N   1 
ATOM 452  C CA  . ARG A 1 208 ? 105.807 136.114 86.844  1.00 78.33  ? 208 ARG B CA  1 
ATOM 453  C C   . ARG A 1 208 ? 105.138 134.749 86.940  1.00 78.33  ? 208 ARG B C   1 
ATOM 454  O O   . ARG A 1 208 ? 105.529 133.930 87.778  1.00 77.69  ? 208 ARG B O   1 
ATOM 455  C CB  . ARG A 1 208 ? 105.141 137.101 87.803  1.00 77.34  ? 208 ARG B CB  1 
ATOM 456  C CG  . ARG A 1 208 ? 105.743 138.497 87.749  1.00 78.23  ? 208 ARG B CG  1 
ATOM 457  C CD  . ARG A 1 208 ? 104.985 139.485 88.614  1.00 80.77  ? 208 ARG B CD  1 
ATOM 458  N NE  . ARG A 1 208 ? 105.459 140.849 88.413  1.00 81.97  ? 208 ARG B NE  1 
ATOM 459  C CZ  . ARG A 1 208 ? 104.952 141.918 89.012  1.00 79.47  ? 208 ARG B CZ  1 
ATOM 460  N NH1 . ARG A 1 208 ? 103.947 141.822 89.867  1.00 78.23  ? 208 ARG B NH1 1 
ATOM 461  N NH2 . ARG A 1 208 ? 105.467 143.115 88.745  1.00 76.20  ? 208 ARG B NH2 1 
ATOM 462  N N   . LYS A 1 209 ? 104.134 134.489 86.099  1.00 73.82  ? 209 LYS B N   1 
ATOM 463  C CA  . LYS A 1 209 ? 103.456 133.198 86.127  1.00 69.87  ? 209 LYS B CA  1 
ATOM 464  C C   . LYS A 1 209 ? 104.346 132.083 85.599  1.00 69.42  ? 209 LYS B C   1 
ATOM 465  O O   . LYS A 1 209 ? 104.257 130.947 86.076  1.00 72.56  ? 209 LYS B O   1 
ATOM 466  C CB  . LYS A 1 209 ? 102.160 133.272 85.319  1.00 70.49  ? 209 LYS B CB  1 
ATOM 467  C CG  . LYS A 1 209 ? 101.530 131.921 85.014  1.00 72.62  ? 209 LYS B CG  1 
ATOM 468  C CD  . LYS A 1 209 ? 100.162 132.074 84.377  1.00 69.85  ? 209 LYS B CD  1 
ATOM 469  C CE  . LYS A 1 209 ? 99.780  130.836 83.587  1.00 71.23  ? 209 LYS B CE  1 
ATOM 470  N NZ  . LYS A 1 209 ? 99.897  129.590 84.391  1.00 67.89  ? 209 LYS B NZ  1 
ATOM 471  N N   . LYS A 1 210 ? 105.194 132.375 84.610  1.00 66.62  ? 210 LYS B N   1 
ATOM 472  C CA  . LYS A 1 210 ? 106.107 131.356 84.101  1.00 68.05  ? 210 LYS B CA  1 
ATOM 473  C C   . LYS A 1 210 ? 107.089 130.911 85.176  1.00 68.56  ? 210 LYS B C   1 
ATOM 474  O O   . LYS A 1 210 ? 107.333 129.711 85.349  1.00 67.25  ? 210 LYS B O   1 
ATOM 475  C CB  . LYS A 1 210 ? 106.869 131.888 82.890  1.00 70.09  ? 210 LYS B CB  1 
ATOM 476  C CG  . LYS A 1 210 ? 106.014 132.180 81.674  1.00 70.19  ? 210 LYS B CG  1 
ATOM 477  C CD  . LYS A 1 210 ? 106.855 132.247 80.405  1.00 71.01  ? 210 LYS B CD  1 
ATOM 478  C CE  . LYS A 1 210 ? 108.066 133.161 80.549  1.00 70.04  ? 210 LYS B CE  1 
ATOM 479  N NZ  . LYS A 1 210 ? 108.861 133.215 79.293  1.00 71.31  ? 210 LYS B NZ  1 
ATOM 480  N N   . TRP A 1 211 ? 107.661 131.866 85.907  1.00 75.37  ? 211 TRP B N   1 
ATOM 481  C CA  . TRP A 1 211 ? 108.664 131.533 86.911  1.00 72.35  ? 211 TRP B CA  1 
ATOM 482  C C   . TRP A 1 211 ? 108.066 130.697 88.035  1.00 71.59  ? 211 TRP B C   1 
ATOM 483  O O   . TRP A 1 211 ? 108.699 129.751 88.517  1.00 75.54  ? 211 TRP B O   1 
ATOM 484  C CB  . TRP A 1 211 ? 109.280 132.817 87.464  1.00 72.97  ? 211 TRP B CB  1 
ATOM 485  C CG  . TRP A 1 211 ? 109.866 133.701 86.403  1.00 75.32  ? 211 TRP B CG  1 
ATOM 486  C CD1 . TRP A 1 211 ? 110.254 133.330 85.148  1.00 75.33  ? 211 TRP B CD1 1 
ATOM 487  C CD2 . TRP A 1 211 ? 110.122 135.108 86.501  1.00 74.17  ? 211 TRP B CD2 1 
ATOM 488  N NE1 . TRP A 1 211 ? 110.740 134.416 84.462  1.00 75.26  ? 211 TRP B NE1 1 
ATOM 489  C CE2 . TRP A 1 211 ? 110.670 135.519 85.270  1.00 74.61  ? 211 TRP B CE2 1 
ATOM 490  C CE3 . TRP A 1 211 ? 109.944 136.059 87.510  1.00 72.86  ? 211 TRP B CE3 1 
ATOM 491  C CZ2 . TRP A 1 211 ? 111.042 136.838 85.023  1.00 74.04  ? 211 TRP B CZ2 1 
ATOM 492  C CZ3 . TRP A 1 211 ? 110.315 137.365 87.263  1.00 73.49  ? 211 TRP B CZ3 1 
ATOM 493  C CH2 . TRP A 1 211 ? 110.857 137.744 86.030  1.00 74.20  ? 211 TRP B CH2 1 
ATOM 494  N N   . ILE A 1 212 ? 106.853 131.036 88.473  1.00 63.01  ? 212 ILE B N   1 
ATOM 495  C CA  . ILE A 1 212 ? 106.217 130.278 89.545  1.00 64.47  ? 212 ILE B CA  1 
ATOM 496  C C   . ILE A 1 212 ? 105.804 128.895 89.060  1.00 65.11  ? 212 ILE B C   1 
ATOM 497  O O   . ILE A 1 212 ? 105.759 127.941 89.846  1.00 66.89  ? 212 ILE B O   1 
ATOM 498  C CB  . ILE A 1 212 ? 105.016 131.064 90.104  1.00 64.43  ? 212 ILE B CB  1 
ATOM 499  C CG1 . ILE A 1 212 ? 105.498 132.366 90.751  1.00 66.21  ? 212 ILE B CG1 1 
ATOM 500  C CG2 . ILE A 1 212 ? 104.234 130.220 91.109  1.00 63.41  ? 212 ILE B CG2 1 
ATOM 501  C CD1 . ILE A 1 212 ? 104.385 133.262 91.253  1.00 65.41  ? 212 ILE B CD1 1 
ATOM 502  N N   . HIS A 1 213 ? 105.487 128.757 87.773  1.00 53.54  ? 213 HIS B N   1 
ATOM 503  C CA  . HIS A 1 213 ? 104.882 127.521 87.294  1.00 52.12  ? 213 HIS B CA  1 
ATOM 504  C C   . HIS A 1 213 ? 105.891 126.384 87.186  1.00 47.95  ? 213 HIS B C   1 
ATOM 505  O O   . HIS A 1 213 ? 105.507 125.216 87.299  1.00 47.83  ? 213 HIS B O   1 
ATOM 506  C CB  . HIS A 1 213 ? 104.211 127.759 85.941  1.00 56.48  ? 213 HIS B CB  1 
ATOM 507  C CG  . HIS A 1 213 ? 103.338 126.630 85.491  1.00 50.99  ? 213 HIS B CG  1 
ATOM 508  N ND1 . HIS A 1 213 ? 103.826 125.541 84.802  1.00 49.40  ? 213 HIS B ND1 1 
ATOM 509  C CD2 . HIS A 1 213 ? 102.008 126.422 85.631  1.00 51.32  ? 213 HIS B CD2 1 
ATOM 510  C CE1 . HIS A 1 213 ? 102.833 124.711 84.537  1.00 49.10  ? 213 HIS B CE1 1 
ATOM 511  N NE2 . HIS A 1 213 ? 101.720 125.222 85.029  1.00 51.44  ? 213 HIS B NE2 1 
ATOM 512  N N   . CYS A 1 214 ? 107.171 126.691 86.960  1.00 53.39  ? 214 CYS B N   1 
ATOM 513  C CA  . CYS A 1 214 ? 108.157 125.660 86.660  1.00 55.80  ? 214 CYS B CA  1 
ATOM 514  C C   . CYS A 1 214 ? 109.462 125.778 87.437  1.00 54.52  ? 214 CYS B C   1 
ATOM 515  O O   . CYS A 1 214 ? 110.358 124.957 87.219  1.00 52.43  ? 214 CYS B O   1 
ATOM 516  C CB  . CYS A 1 214 ? 108.481 125.663 85.157  1.00 56.20  ? 214 CYS B CB  1 
ATOM 517  S SG  . CYS A 1 214 ? 107.058 125.335 84.086  1.00 57.60  ? 214 CYS B SG  1 
ATOM 518  N N   . PHE A 1 215 ? 109.605 126.759 88.328  1.00 61.34  ? 215 PHE B N   1 
ATOM 519  C CA  . PHE A 1 215 ? 110.866 126.973 89.023  1.00 64.26  ? 215 PHE B CA  1 
ATOM 520  C C   . PHE A 1 215 ? 110.734 127.117 90.533  1.00 67.85  ? 215 PHE B C   1 
ATOM 521  O O   . PHE A 1 215 ? 111.748 127.346 91.199  1.00 69.76  ? 215 PHE B O   1 
ATOM 522  C CB  . PHE A 1 215 ? 111.578 128.223 88.471  1.00 64.14  ? 215 PHE B CB  1 
ATOM 523  C CG  . PHE A 1 215 ? 112.158 128.045 87.091  1.00 64.47  ? 215 PHE B CG  1 
ATOM 524  C CD1 . PHE A 1 215 ? 112.825 126.882 86.740  1.00 64.48  ? 215 PHE B CD1 1 
ATOM 525  C CD2 . PHE A 1 215 ? 112.043 129.052 86.147  1.00 68.26  ? 215 PHE B CD2 1 
ATOM 526  C CE1 . PHE A 1 215 ? 113.358 126.726 85.477  1.00 64.30  ? 215 PHE B CE1 1 
ATOM 527  C CE2 . PHE A 1 215 ? 112.576 128.898 84.880  1.00 67.62  ? 215 PHE B CE2 1 
ATOM 528  C CZ  . PHE A 1 215 ? 113.233 127.735 84.548  1.00 65.17  ? 215 PHE B CZ  1 
ATOM 529  N N   . GLU A 1 216 ? 109.534 126.981 91.100  1.00 70.61  ? 216 GLU B N   1 
ATOM 530  C CA  . GLU A 1 216 ? 109.396 127.127 92.545  1.00 71.09  ? 216 GLU B CA  1 
ATOM 531  C C   . GLU A 1 216 ? 110.074 126.007 93.318  1.00 75.44  ? 216 GLU B C   1 
ATOM 532  O O   . GLU A 1 216 ? 110.234 126.129 94.537  1.00 73.11  ? 216 GLU B O   1 
ATOM 533  C CB  . GLU A 1 216 ? 107.923 127.185 92.944  1.00 70.02  ? 216 GLU B CB  1 
ATOM 534  C CG  . GLU A 1 216 ? 107.350 128.586 92.964  1.00 75.63  ? 216 GLU B CG  1 
ATOM 535  C CD  . GLU A 1 216 ? 106.139 128.712 93.868  1.00 75.88  ? 216 GLU B CD  1 
ATOM 536  O OE1 . GLU A 1 216 ? 105.525 127.674 94.196  1.00 73.04  ? 216 GLU B OE1 1 
ATOM 537  O OE2 . GLU A 1 216 ? 105.802 129.849 94.257  1.00 73.89  ? 216 GLU B OE2 1 
ATOM 538  N N   . GLY A 1 217 ? 110.466 124.929 92.652  1.00 75.70  ? 217 GLY B N   1 
ATOM 539  C CA  . GLY A 1 217 ? 111.109 123.813 93.305  1.00 71.87  ? 217 GLY B CA  1 
ATOM 540  C C   . GLY A 1 217 ? 112.613 123.898 93.379  1.00 74.02  ? 217 GLY B C   1 
ATOM 541  O O   . GLY A 1 217 ? 113.249 122.963 93.875  1.00 76.38  ? 217 GLY B O   1 
ATOM 542  N N   . VAL A 1 218 ? 113.211 124.992 92.911  1.00 71.88  ? 218 VAL B N   1 
ATOM 543  C CA  . VAL A 1 218 ? 114.664 125.106 92.879  1.00 72.25  ? 218 VAL B CA  1 
ATOM 544  C C   . VAL A 1 218 ? 115.167 125.220 94.311  1.00 72.03  ? 218 VAL B C   1 
ATOM 545  O O   . VAL A 1 218 ? 114.388 125.480 95.233  1.00 70.60  ? 218 VAL B O   1 
ATOM 546  C CB  . VAL A 1 218 ? 115.125 126.303 92.024  1.00 71.50  ? 218 VAL B CB  1 
ATOM 547  C CG1 . VAL A 1 218 ? 114.670 126.135 90.567  1.00 69.50  ? 218 VAL B CG1 1 
ATOM 548  C CG2 . VAL A 1 218 ? 114.634 127.623 92.618  1.00 70.34  ? 218 VAL B CG2 1 
ATOM 549  N N   . THR A 1 219 ? 116.469 125.022 94.509  1.00 69.44  ? 219 THR B N   1 
ATOM 550  C CA  . THR A 1 219 ? 117.040 125.069 95.850  1.00 70.47  ? 219 THR B CA  1 
ATOM 551  C C   . THR A 1 219 ? 117.310 126.498 96.312  1.00 71.09  ? 219 THR B C   1 
ATOM 552  O O   . THR A 1 219 ? 116.598 127.016 97.177  1.00 71.51  ? 219 THR B O   1 
ATOM 553  C CB  . THR A 1 219 ? 118.328 124.246 95.895  1.00 69.97  ? 219 THR B CB  1 
ATOM 554  O OG1 . THR A 1 219 ? 119.239 124.720 94.898  1.00 72.06  ? 219 THR B OG1 1 
ATOM 555  C CG2 . THR A 1 219 ? 118.011 122.797 95.639  1.00 71.07  ? 219 THR B CG2 1 
ATOM 556  N N   . ALA A 1 220 ? 118.317 127.151 95.738  1.00 66.69  ? 220 ALA B N   1 
ATOM 557  C CA  . ALA A 1 220 ? 118.759 128.460 96.208  1.00 65.02  ? 220 ALA B CA  1 
ATOM 558  C C   . ALA A 1 220 ? 118.972 129.377 95.013  1.00 67.94  ? 220 ALA B C   1 
ATOM 559  O O   . ALA A 1 220 ? 119.936 129.207 94.261  1.00 70.64  ? 220 ALA B O   1 
ATOM 560  C CB  . ALA A 1 220 ? 120.038 128.337 97.035  1.00 66.72  ? 220 ALA B CB  1 
ATOM 561  N N   . ILE A 1 221 ? 118.092 130.367 94.857  1.00 70.34  ? 221 ILE B N   1 
ATOM 562  C CA  . ILE A 1 221 ? 118.161 131.256 93.705  1.00 72.01  ? 221 ILE B CA  1 
ATOM 563  C C   . ILE A 1 221 ? 119.366 132.175 93.838  1.00 72.72  ? 221 ILE B C   1 
ATOM 564  O O   . ILE A 1 221 ? 119.625 132.744 94.906  1.00 74.26  ? 221 ILE B O   1 
ATOM 565  C CB  . ILE A 1 221 ? 116.863 132.069 93.559  1.00 72.75  ? 221 ILE B CB  1 
ATOM 566  C CG1 . ILE A 1 221 ? 115.643 131.146 93.595  1.00 72.85  ? 221 ILE B CG1 1 
ATOM 567  C CG2 . ILE A 1 221 ? 116.880 132.854 92.252  1.00 71.89  ? 221 ILE B CG2 1 
ATOM 568  C CD1 . ILE A 1 221 ? 114.319 131.876 93.526  1.00 71.40  ? 221 ILE B CD1 1 
ATOM 569  N N   . ILE A 1 222 ? 120.095 132.340 92.739  1.00 77.91  ? 222 ILE B N   1 
ATOM 570  C CA  . ILE A 1 222 ? 121.289 133.172 92.686  1.00 79.38  ? 222 ILE B CA  1 
ATOM 571  C C   . ILE A 1 222 ? 121.004 134.347 91.765  1.00 79.28  ? 222 ILE B C   1 
ATOM 572  O O   . ILE A 1 222 ? 120.594 134.154 90.616  1.00 80.51  ? 222 ILE B O   1 
ATOM 573  C CB  . ILE A 1 222 ? 122.510 132.377 92.188  1.00 78.51  ? 222 ILE B CB  1 
ATOM 574  C CG1 . ILE A 1 222 ? 122.876 131.295 93.209  1.00 78.43  ? 222 ILE B CG1 1 
ATOM 575  C CG2 . ILE A 1 222 ? 123.676 133.321 91.899  1.00 77.62  ? 222 ILE B CG2 1 
ATOM 576  C CD1 . ILE A 1 222 ? 123.886 130.286 92.721  1.00 78.55  ? 222 ILE B CD1 1 
ATOM 577  N N   . PHE A 1 223 ? 121.215 135.561 92.268  1.00 83.82  ? 223 PHE B N   1 
ATOM 578  C CA  . PHE A 1 223 ? 121.072 136.776 91.476  1.00 83.59  ? 223 PHE B CA  1 
ATOM 579  C C   . PHE A 1 223 ? 122.371 137.563 91.543  1.00 84.09  ? 223 PHE B C   1 
ATOM 580  O O   . PHE A 1 223 ? 122.746 138.055 92.612  1.00 84.28  ? 223 PHE B O   1 
ATOM 581  C CB  . PHE A 1 223 ? 119.908 137.633 91.971  1.00 84.86  ? 223 PHE B CB  1 
ATOM 582  C CG  . PHE A 1 223 ? 119.846 138.983 91.324  1.00 85.81  ? 223 PHE B CG  1 
ATOM 583  C CD1 . PHE A 1 223 ? 119.498 139.107 89.989  1.00 85.80  ? 223 PHE B CD1 1 
ATOM 584  C CD2 . PHE A 1 223 ? 120.145 140.128 92.042  1.00 86.13  ? 223 PHE B CD2 1 
ATOM 585  C CE1 . PHE A 1 223 ? 119.445 140.349 89.383  1.00 85.51  ? 223 PHE B CE1 1 
ATOM 586  C CE2 . PHE A 1 223 ? 120.093 141.374 91.440  1.00 85.57  ? 223 PHE B CE2 1 
ATOM 587  C CZ  . PHE A 1 223 ? 119.743 141.482 90.110  1.00 84.46  ? 223 PHE B CZ  1 
ATOM 588  N N   . CYS A 1 224 ? 123.046 137.690 90.406  1.00 88.32  ? 224 CYS B N   1 
ATOM 589  C CA  . CYS A 1 224 ? 124.288 138.448 90.337  1.00 89.13  ? 224 CYS B CA  1 
ATOM 590  C C   . CYS A 1 224 ? 123.988 139.922 90.097  1.00 88.44  ? 224 CYS B C   1 
ATOM 591  O O   . CYS A 1 224 ? 122.827 140.323 90.027  1.00 88.75  ? 224 CYS B O   1 
ATOM 592  C CB  . CYS A 1 224 ? 125.197 137.906 89.231  1.00 88.91  ? 224 CYS B CB  1 
ATOM 593  S SG  . CYS A 1 224 ? 125.683 136.173 89.437  1.00 91.94  ? 224 CYS B SG  1 
ATOM 594  N N   . THR A 1 262 ? 113.084 129.535 99.135  1.00 81.30  ? 262 THR B N   1 
ATOM 595  C CA  . THR A 1 262 ? 114.419 129.391 98.573  1.00 81.79  ? 262 THR B CA  1 
ATOM 596  C C   . THR A 1 262 ? 115.407 130.259 99.352  1.00 80.27  ? 262 THR B C   1 
ATOM 597  O O   . THR A 1 262 ? 115.098 130.711 100.450 1.00 81.84  ? 262 THR B O   1 
ATOM 598  C CB  . THR A 1 262 ? 114.435 129.782 97.086  1.00 81.16  ? 262 THR B CB  1 
ATOM 599  O OG1 . THR A 1 262 ? 114.184 131.186 96.955  1.00 79.64  ? 262 THR B OG1 1 
ATOM 600  C CG2 . THR A 1 262 ? 113.366 129.004 96.319  1.00 80.35  ? 262 THR B CG2 1 
ATOM 601  N N   . SER A 1 263 ? 116.592 130.484 98.788  1.00 73.90  ? 263 SER B N   1 
ATOM 602  C CA  . SER A 1 263 ? 117.600 131.349 99.383  1.00 74.59  ? 263 SER B CA  1 
ATOM 603  C C   . SER A 1 263 ? 118.129 132.297 98.318  1.00 75.35  ? 263 SER B C   1 
ATOM 604  O O   . SER A 1 263 ? 117.905 132.106 97.121  1.00 77.69  ? 263 SER B O   1 
ATOM 605  C CB  . SER A 1 263 ? 118.762 130.548 99.990  1.00 75.32  ? 263 SER B CB  1 
ATOM 606  O OG  . SER A 1 263 ? 119.781 131.407 100.474 1.00 76.41  ? 263 SER B OG  1 
ATOM 607  N N   . ILE A 1 264 ? 118.831 133.333 98.770  1.00 74.25  ? 264 ILE B N   1 
ATOM 608  C CA  . ILE A 1 264 ? 119.383 134.363 97.897  1.00 74.52  ? 264 ILE B CA  1 
ATOM 609  C C   . ILE A 1 264 ? 120.899 134.316 97.993  1.00 76.86  ? 264 ILE B C   1 
ATOM 610  O O   . ILE A 1 264 ? 121.463 134.374 99.092  1.00 78.39  ? 264 ILE B O   1 
ATOM 611  C CB  . ILE A 1 264 ? 118.868 135.760 98.266  1.00 76.89  ? 264 ILE B CB  1 
ATOM 612  C CG1 . ILE A 1 264 ? 117.339 135.790 98.278  1.00 77.30  ? 264 ILE B CG1 1 
ATOM 613  C CG2 . ILE A 1 264 ? 119.431 136.792 97.303  1.00 76.97  ? 264 ILE B CG2 1 
ATOM 614  C CD1 . ILE A 1 264 ? 116.710 135.456 96.956  1.00 76.73  ? 264 ILE B CD1 1 
ATOM 615  N N   . ILE A 1 265 ? 121.555 134.205 96.843  1.00 79.41  ? 265 ILE B N   1 
ATOM 616  C CA  . ILE A 1 265 ? 123.000 134.344 96.729  1.00 80.03  ? 265 ILE B CA  1 
ATOM 617  C C   . ILE A 1 265 ? 123.271 135.516 95.798  1.00 81.50  ? 265 ILE B C   1 
ATOM 618  O O   . ILE A 1 265 ? 122.695 135.592 94.706  1.00 82.04  ? 265 ILE B O   1 
ATOM 619  C CB  . ILE A 1 265 ? 123.648 133.046 96.217  1.00 79.54  ? 265 ILE B CB  1 
ATOM 620  C CG1 . ILE A 1 265 ? 123.226 131.874 97.106  1.00 79.41  ? 265 ILE B CG1 1 
ATOM 621  C CG2 . ILE A 1 265 ? 125.160 133.163 96.209  1.00 80.60  ? 265 ILE B CG2 1 
ATOM 622  C CD1 . ILE A 1 265 ? 123.812 130.545 96.700  1.00 80.29  ? 265 ILE B CD1 1 
ATOM 623  N N   . LEU A 1 266 ? 124.131 136.435 96.230  1.00 86.97  ? 266 LEU B N   1 
ATOM 624  C CA  . LEU A 1 266 ? 124.369 137.679 95.514  1.00 85.77  ? 266 LEU B CA  1 
ATOM 625  C C   . LEU A 1 266 ? 125.829 137.785 95.095  1.00 86.73  ? 266 LEU B C   1 
ATOM 626  O O   . LEU A 1 266 ? 126.736 137.382 95.829  1.00 86.10  ? 266 LEU B O   1 
ATOM 627  C CB  . LEU A 1 266 ? 123.993 138.889 96.378  1.00 85.53  ? 266 LEU B CB  1 
ATOM 628  C CG  . LEU A 1 266 ? 122.549 138.948 96.883  1.00 86.78  ? 266 LEU B CG  1 
ATOM 629  C CD1 . LEU A 1 266 ? 122.368 140.104 97.857  1.00 85.55  ? 266 LEU B CD1 1 
ATOM 630  C CD2 . LEU A 1 266 ? 121.565 139.061 95.732  1.00 86.95  ? 266 LEU B CD2 1 
ATOM 631  N N   . PHE A 1 267 ? 126.043 138.344 93.908  1.00 94.21  ? 267 PHE B N   1 
ATOM 632  C CA  . PHE A 1 267 ? 127.387 138.567 93.388  1.00 94.73  ? 267 PHE B CA  1 
ATOM 633  C C   . PHE A 1 267 ? 127.480 139.923 92.702  1.00 94.15  ? 267 PHE B C   1 
ATOM 634  O O   . PHE A 1 267 ? 126.750 140.198 91.750  1.00 92.49  ? 267 PHE B O   1 
ATOM 635  C CB  . PHE A 1 267 ? 127.778 137.459 92.412  1.00 94.04  ? 267 PHE B CB  1 
ATOM 636  C CG  . PHE A 1 267 ? 128.050 136.145 93.074  1.00 94.23  ? 267 PHE B CG  1 
ATOM 637  C CD1 . PHE A 1 267 ? 129.218 135.948 93.788  1.00 93.92  ? 267 PHE B CD1 1 
ATOM 638  C CD2 . PHE A 1 267 ? 127.141 135.105 92.984  1.00 94.40  ? 267 PHE B CD2 1 
ATOM 639  C CE1 . PHE A 1 267 ? 129.472 134.743 94.398  1.00 93.80  ? 267 PHE B CE1 1 
ATOM 640  C CE2 . PHE A 1 267 ? 127.396 133.897 93.595  1.00 95.09  ? 267 PHE B CE2 1 
ATOM 641  C CZ  . PHE A 1 267 ? 128.562 133.720 94.301  1.00 95.16  ? 267 PHE B CZ  1 
ATOM 642  N N   . THR A 1 316 ? 114.987 130.729 106.668 1.00 95.54  ? 316 THR B N   1 
ATOM 643  C CA  . THR A 1 316 ? 114.071 130.244 105.644 1.00 96.12  ? 316 THR B CA  1 
ATOM 644  C C   . THR A 1 316 ? 114.450 130.790 104.276 1.00 96.46  ? 316 THR B C   1 
ATOM 645  O O   . THR A 1 316 ? 114.424 130.073 103.276 1.00 96.52  ? 316 THR B O   1 
ATOM 646  C CB  . THR A 1 316 ? 112.617 130.646 105.943 1.00 97.11  ? 316 THR B CB  1 
ATOM 647  O OG1 . THR A 1 316 ? 112.529 132.070 106.077 1.00 97.16  ? 316 THR B OG1 1 
ATOM 648  C CG2 . THR A 1 316 ? 112.131 129.987 107.219 1.00 95.60  ? 316 THR B CG2 1 
ATOM 649  N N   . LYS A 1 317 ? 114.797 132.070 104.246 1.00 90.86  ? 317 LYS B N   1 
ATOM 650  C CA  . LYS A 1 317 ? 115.092 132.792 103.015 1.00 90.78  ? 317 LYS B CA  1 
ATOM 651  C C   . LYS A 1 317 ? 116.457 133.457 103.161 1.00 91.17  ? 317 LYS B C   1 
ATOM 652  O O   . LYS A 1 317 ? 116.631 134.630 102.822 1.00 90.54  ? 317 LYS B O   1 
ATOM 653  C CB  . LYS A 1 317 ? 113.979 133.795 102.712 1.00 89.89  ? 317 LYS B CB  1 
ATOM 654  C CG  . LYS A 1 317 ? 112.734 133.109 102.173 1.00 90.18  ? 317 LYS B CG  1 
ATOM 655  C CD  . LYS A 1 317 ? 111.743 134.058 101.527 1.00 90.47  ? 317 LYS B CD  1 
ATOM 656  C CE  . LYS A 1 317 ? 110.495 133.308 101.071 1.00 90.42  ? 317 LYS B CE  1 
ATOM 657  N NZ  . LYS A 1 317 ? 109.841 132.560 102.183 1.00 91.51  ? 317 LYS B NZ  1 
ATOM 658  N N   . GLU A 1 318 ? 117.420 132.682 103.661 1.00 91.27  ? 318 GLU B N   1 
ATOM 659  C CA  . GLU A 1 318 ? 118.779 133.170 103.860 1.00 91.04  ? 318 GLU B CA  1 
ATOM 660  C C   . GLU A 1 318 ? 119.236 134.016 102.678 1.00 90.63  ? 318 GLU B C   1 
ATOM 661  O O   . GLU A 1 318 ? 118.941 133.708 101.520 1.00 92.52  ? 318 GLU B O   1 
ATOM 662  C CB  . GLU A 1 318 ? 119.745 131.993 104.037 1.00 91.23  ? 318 GLU B CB  1 
ATOM 663  C CG  . GLU A 1 318 ? 119.487 131.079 105.243 1.00 92.23  ? 318 GLU B CG  1 
ATOM 664  C CD  . GLU A 1 318 ? 118.516 129.940 104.961 1.00 91.89  ? 318 GLU B CD  1 
ATOM 665  O OE1 . GLU A 1 318 ? 118.348 129.567 103.780 1.00 92.08  ? 318 GLU B OE1 1 
ATOM 666  O OE2 . GLU A 1 318 ? 117.928 129.411 105.930 1.00 90.63  ? 318 GLU B OE2 1 
ATOM 667  N N   . ILE A 1 319 ? 119.950 135.097 102.980 1.00 86.56  ? 319 ILE B N   1 
ATOM 668  C CA  . ILE A 1 319 ? 120.546 135.973 101.979 1.00 87.10  ? 319 ILE B CA  1 
ATOM 669  C C   . ILE A 1 319 ? 122.042 136.036 102.254 1.00 87.69  ? 319 ILE B C   1 
ATOM 670  O O   . ILE A 1 319 ? 122.456 136.267 103.395 1.00 88.37  ? 319 ILE B O   1 
ATOM 671  C CB  . ILE A 1 319 ? 119.914 137.379 102.003 1.00 86.07  ? 319 ILE B CB  1 
ATOM 672  C CG1 . ILE A 1 319 ? 118.389 137.273 101.865 1.00 87.72  ? 319 ILE B CG1 1 
ATOM 673  C CG2 . ILE A 1 319 ? 120.514 138.258 100.902 1.00 85.76  ? 319 ILE B CG2 1 
ATOM 674  C CD1 . ILE A 1 319 ? 117.667 138.607 101.747 1.00 87.39  ? 319 ILE B CD1 1 
ATOM 675  N N   . TYR A 1 320 ? 122.847 135.818 101.217 1.00 83.65  ? 320 TYR B N   1 
ATOM 676  C CA  . TYR A 1 320 ? 124.298 135.825 101.332 1.00 83.07  ? 320 TYR B CA  1 
ATOM 677  C C   . TYR A 1 320 ? 124.889 136.677 100.215 1.00 84.78  ? 320 TYR B C   1 
ATOM 678  O O   . TYR A 1 320 ? 124.347 136.714 99.107  1.00 86.57  ? 320 TYR B O   1 
ATOM 679  C CB  . TYR A 1 320 ? 124.870 134.400 101.261 1.00 83.49  ? 320 TYR B CB  1 
ATOM 680  C CG  . TYR A 1 320 ? 124.261 133.391 102.215 1.00 84.62  ? 320 TYR B CG  1 
ATOM 681  C CD1 . TYR A 1 320 ? 124.620 133.368 103.558 1.00 86.24  ? 320 TYR B CD1 1 
ATOM 682  C CD2 . TYR A 1 320 ? 123.360 132.434 101.763 1.00 84.10  ? 320 TYR B CD2 1 
ATOM 683  C CE1 . TYR A 1 320 ? 124.079 132.433 104.429 1.00 84.66  ? 320 TYR B CE1 1 
ATOM 684  C CE2 . TYR A 1 320 ? 122.816 131.499 102.624 1.00 83.01  ? 320 TYR B CE2 1 
ATOM 685  C CZ  . TYR A 1 320 ? 123.181 131.501 103.953 1.00 83.79  ? 320 TYR B CZ  1 
ATOM 686  O OH  . TYR A 1 320 ? 122.635 130.570 104.804 1.00 82.91  ? 320 TYR B OH  1 
ATOM 687  N N   . THR A 1 321 ? 125.998 137.364 100.504 1.00 90.09  ? 321 THR B N   1 
ATOM 688  C CA  . THR A 1 321 ? 126.644 138.241 99.532  1.00 90.84  ? 321 THR B CA  1 
ATOM 689  C C   . THR A 1 321 ? 128.144 137.971 99.456  1.00 90.35  ? 321 THR B C   1 
ATOM 690  O O   . THR A 1 321 ? 128.772 137.589 100.448 1.00 89.55  ? 321 THR B O   1 
ATOM 691  C CB  . THR A 1 321 ? 126.391 139.716 99.871  1.00 91.03  ? 321 THR B CB  1 
ATOM 692  O OG1 . THR A 1 321 ? 125.003 139.902 100.181 1.00 90.03  ? 321 THR B OG1 1 
ATOM 693  C CG2 . THR A 1 321 ? 126.754 140.605 98.691  1.00 89.78  ? 321 THR B CG2 1 
ATOM 694  N N   . HIS A 1 322 ? 128.701 138.176 98.262  1.00 96.05  ? 322 HIS B N   1 
ATOM 695  C CA  . HIS A 1 322 ? 130.092 137.871 97.941  1.00 96.43  ? 322 HIS B CA  1 
ATOM 696  C C   . HIS A 1 322 ? 130.415 138.566 96.625  1.00 98.17  ? 322 HIS B C   1 
ATOM 697  O O   . HIS A 1 322 ? 129.520 139.044 95.924  1.00 98.93  ? 322 HIS B O   1 
ATOM 698  C CB  . HIS A 1 322 ? 130.321 136.358 97.843  1.00 96.94  ? 322 HIS B CB  1 
ATOM 699  C CG  . HIS A 1 322 ? 131.748 135.965 97.607  1.00 98.17  ? 322 HIS B CG  1 
ATOM 700  N ND1 . HIS A 1 322 ? 132.286 135.840 96.344  1.00 98.50  ? 322 HIS B ND1 1 
ATOM 701  C CD2 . HIS A 1 322 ? 132.744 135.658 98.472  1.00 98.05  ? 322 HIS B CD2 1 
ATOM 702  C CE1 . HIS A 1 322 ? 133.554 135.479 96.441  1.00 98.08  ? 322 HIS B CE1 1 
ATOM 703  N NE2 . HIS A 1 322 ? 133.856 135.361 97.721  1.00 98.64  ? 322 HIS B NE2 1 
ATOM 704  N N   . PHE A 1 323 ? 131.703 138.624 96.295  1.00 102.99 ? 323 PHE B N   1 
ATOM 705  C CA  . PHE A 1 323 ? 132.132 139.203 95.023  1.00 103.28 ? 323 PHE B CA  1 
ATOM 706  C C   . PHE A 1 323 ? 133.387 138.521 94.487  1.00 103.17 ? 323 PHE B C   1 
ATOM 707  O O   . PHE A 1 323 ? 133.656 138.555 93.285  1.00 103.17 ? 323 PHE B O   1 
ATOM 708  C CB  . PHE A 1 323 ? 132.385 140.702 95.178  1.00 102.50 ? 323 PHE B CB  1 
ATOM 709  C CG  . PHE A 1 323 ? 131.194 141.467 95.665  1.00 102.99 ? 323 PHE B CG  1 
ATOM 710  C CD1 . PHE A 1 323 ? 130.220 141.895 94.779  1.00 103.50 ? 323 PHE B CD1 1 
ATOM 711  C CD2 . PHE A 1 323 ? 131.041 141.750 97.012  1.00 103.23 ? 323 PHE B CD2 1 
ATOM 712  C CE1 . PHE A 1 323 ? 129.118 142.598 95.228  1.00 103.94 ? 323 PHE B CE1 1 
ATOM 713  C CE2 . PHE A 1 323 ? 129.941 142.452 97.466  1.00 103.11 ? 323 PHE B CE2 1 
ATOM 714  C CZ  . PHE A 1 323 ? 128.979 142.875 96.573  1.00 103.17 ? 323 PHE B CZ  1 
ATOM 715  N N   . THR A 1 329 ? 137.513 132.226 91.516  1.00 104.55 ? 329 THR B N   1 
ATOM 716  C CA  . THR A 1 329 ? 137.709 130.967 92.225  1.00 105.63 ? 329 THR B CA  1 
ATOM 717  C C   . THR A 1 329 ? 136.942 130.965 93.544  1.00 105.92 ? 329 THR B C   1 
ATOM 718  O O   . THR A 1 329 ? 136.430 129.932 93.975  1.00 106.03 ? 329 THR B O   1 
ATOM 719  C CB  . THR A 1 329 ? 139.200 130.709 92.508  1.00 105.88 ? 329 THR B CB  1 
ATOM 720  O OG1 . THR A 1 329 ? 139.969 130.989 91.333  1.00 105.94 ? 329 THR B OG1 1 
ATOM 721  C CG2 . THR A 1 329 ? 139.424 129.261 92.924  1.00 105.62 ? 329 THR B CG2 1 
ATOM 722  N N   . LYS A 1 330 ? 136.873 132.134 94.184  1.00 104.54 ? 330 LYS B N   1 
ATOM 723  C CA  . LYS A 1 330 ? 136.188 132.244 95.469  1.00 103.87 ? 330 LYS B CA  1 
ATOM 724  C C   . LYS A 1 330 ? 134.671 132.262 95.318  1.00 103.38 ? 330 LYS B C   1 
ATOM 725  O O   . LYS A 1 330 ? 133.961 131.831 96.234  1.00 102.54 ? 330 LYS B O   1 
ATOM 726  C CB  . LYS A 1 330 ? 136.650 133.497 96.222  1.00 104.40 ? 330 LYS B CB  1 
ATOM 727  C CG  . LYS A 1 330 ? 138.103 133.486 96.689  1.00 104.46 ? 330 LYS B CG  1 
ATOM 728  C CD  . LYS A 1 330 ? 138.475 134.780 97.404  1.00 104.09 ? 330 LYS B CD  1 
ATOM 729  C CE  . LYS A 1 330 ? 139.916 134.764 97.893  1.00 103.75 ? 330 LYS B CE  1 
ATOM 730  N NZ  . LYS A 1 330 ? 140.309 136.030 98.575  1.00 103.73 ? 330 LYS B NZ  1 
ATOM 731  N N   . ASN A 1 331 ? 134.155 132.756 94.191  1.00 98.94  ? 331 ASN B N   1 
ATOM 732  C CA  . ASN A 1 331 ? 132.707 132.815 94.016  1.00 98.79  ? 331 ASN B CA  1 
ATOM 733  C C   . ASN A 1 331 ? 132.094 131.420 94.018  1.00 99.02  ? 331 ASN B C   1 
ATOM 734  O O   . ASN A 1 331 ? 131.042 131.194 94.630  1.00 99.59  ? 331 ASN B O   1 
ATOM 735  C CB  . ASN A 1 331 ? 132.366 133.544 92.718  1.00 99.59  ? 331 ASN B CB  1 
ATOM 736  C CG  . ASN A 1 331 ? 132.917 134.953 92.680  1.00 100.12 ? 331 ASN B CG  1 
ATOM 737  O OD1 . ASN A 1 331 ? 132.308 135.885 93.205  1.00 100.03 ? 331 ASN B OD1 1 
ATOM 738  N ND2 . ASN A 1 331 ? 134.075 135.118 92.051  1.00 98.82  ? 331 ASN B ND2 1 
ATOM 739  N N   . VAL A 1 332 ? 132.738 130.469 93.340  1.00 97.72  ? 332 VAL B N   1 
ATOM 740  C CA  . VAL A 1 332 ? 132.204 129.112 93.279  1.00 97.94  ? 332 VAL B CA  1 
ATOM 741  C C   . VAL A 1 332 ? 132.144 128.508 94.675  1.00 98.57  ? 332 VAL B C   1 
ATOM 742  O O   . VAL A 1 332 ? 131.154 127.866 95.051  1.00 98.51  ? 332 VAL B O   1 
ATOM 743  C CB  . VAL A 1 332 ? 133.050 128.248 92.326  1.00 99.30  ? 332 VAL B CB  1 
ATOM 744  C CG1 . VAL A 1 332 ? 132.418 126.873 92.146  1.00 98.54  ? 332 VAL B CG1 1 
ATOM 745  C CG2 . VAL A 1 332 ? 133.223 128.941 90.981  1.00 98.37  ? 332 VAL B CG2 1 
ATOM 746  N N   . GLN A 1 333 ? 133.201 128.701 95.465  1.00 96.90  ? 333 GLN B N   1 
ATOM 747  C CA  . GLN A 1 333 ? 133.206 128.192 96.832  1.00 97.07  ? 333 GLN B CA  1 
ATOM 748  C C   . GLN A 1 333 ? 132.117 128.853 97.665  1.00 96.66  ? 333 GLN B C   1 
ATOM 749  O O   . GLN A 1 333 ? 131.507 128.212 98.528  1.00 95.87  ? 333 GLN B O   1 
ATOM 750  C CB  . GLN A 1 333 ? 134.577 128.419 97.465  1.00 96.63  ? 333 GLN B CB  1 
ATOM 751  C CG  . GLN A 1 333 ? 134.716 127.838 98.858  1.00 96.11  ? 333 GLN B CG  1 
ATOM 752  C CD  . GLN A 1 333 ? 136.153 127.795 99.324  1.00 96.87  ? 333 GLN B CD  1 
ATOM 753  O OE1 . GLN A 1 333 ? 137.054 128.279 98.641  1.00 96.62  ? 333 GLN B OE1 1 
ATOM 754  N NE2 . GLN A 1 333 ? 136.377 127.210 100.495 1.00 96.38  ? 333 GLN B NE2 1 
ATOM 755  N N   . PHE A 1 334 ? 131.870 130.142 97.433  1.00 93.67  ? 334 PHE B N   1 
ATOM 756  C CA  . PHE A 1 334 ? 130.807 130.830 98.155  1.00 93.24  ? 334 PHE B CA  1 
ATOM 757  C C   . PHE A 1 334 ? 129.440 130.241 97.819  1.00 93.73  ? 334 PHE B C   1 
ATOM 758  O O   . PHE A 1 334 ? 128.607 130.036 98.713  1.00 95.37  ? 334 PHE B O   1 
ATOM 759  C CB  . PHE A 1 334 ? 130.859 132.320 97.831  1.00 93.82  ? 334 PHE B CB  1 
ATOM 760  C CG  . PHE A 1 334 ? 129.795 133.123 98.503  1.00 93.62  ? 334 PHE B CG  1 
ATOM 761  C CD1 . PHE A 1 334 ? 129.932 133.509 99.825  1.00 93.46  ? 334 PHE B CD1 1 
ATOM 762  C CD2 . PHE A 1 334 ? 128.661 133.505 97.812  1.00 92.94  ? 334 PHE B CD2 1 
ATOM 763  C CE1 . PHE A 1 334 ? 128.952 134.255 100.441 1.00 93.25  ? 334 PHE B CE1 1 
ATOM 764  C CE2 . PHE A 1 334 ? 127.684 134.251 98.424  1.00 92.70  ? 334 PHE B CE2 1 
ATOM 765  C CZ  . PHE A 1 334 ? 127.830 134.628 99.735  1.00 93.38  ? 334 PHE B CZ  1 
ATOM 766  N N   . VAL A 1 335 ? 129.191 129.957 96.538  1.00 91.14  ? 335 VAL B N   1 
ATOM 767  C CA  . VAL A 1 335 ? 127.941 129.300 96.160  1.00 90.84  ? 335 VAL B CA  1 
ATOM 768  C C   . VAL A 1 335 ? 127.850 127.931 96.818  1.00 90.94  ? 335 VAL B C   1 
ATOM 769  O O   . VAL A 1 335 ? 126.779 127.510 97.277  1.00 90.41  ? 335 VAL B O   1 
ATOM 770  C CB  . VAL A 1 335 ? 127.830 129.184 94.629  1.00 90.77  ? 335 VAL B CB  1 
ATOM 771  C CG1 . VAL A 1 335 ? 126.578 128.413 94.250  1.00 90.04  ? 335 VAL B CG1 1 
ATOM 772  C CG2 . VAL A 1 335 ? 127.837 130.554 93.980  1.00 89.82  ? 335 VAL B CG2 1 
ATOM 773  N N   . PHE A 1 336 ? 128.969 127.208 96.852  1.00 88.47  ? 336 PHE B N   1 
ATOM 774  C CA  . PHE A 1 336 ? 128.996 125.896 97.487  1.00 88.12  ? 336 PHE B CA  1 
ATOM 775  C C   . PHE A 1 336 ? 128.585 125.992 98.950  1.00 88.65  ? 336 PHE B C   1 
ATOM 776  O O   . PHE A 1 336 ? 127.729 125.234 99.422  1.00 89.61  ? 336 PHE B O   1 
ATOM 777  C CB  . PHE A 1 336 ? 130.399 125.304 97.348  1.00 87.91  ? 336 PHE B CB  1 
ATOM 778  C CG  . PHE A 1 336 ? 130.602 124.024 98.098  1.00 88.08  ? 336 PHE B CG  1 
ATOM 779  C CD1 . PHE A 1 336 ? 129.956 122.866 97.706  1.00 89.50  ? 336 PHE B CD1 1 
ATOM 780  C CD2 . PHE A 1 336 ? 131.459 123.973 99.184  1.00 88.06  ? 336 PHE B CD2 1 
ATOM 781  C CE1 . PHE A 1 336 ? 130.147 121.684 98.391  1.00 89.97  ? 336 PHE B CE1 1 
ATOM 782  C CE2 . PHE A 1 336 ? 131.655 122.793 99.873  1.00 89.21  ? 336 PHE B CE2 1 
ATOM 783  C CZ  . PHE A 1 336 ? 130.998 121.647 99.474  1.00 89.22  ? 336 PHE B CZ  1 
ATOM 784  N N   . ASP A 1 337 ? 129.178 126.938 99.679  1.00 86.85  ? 337 ASP B N   1 
ATOM 785  C CA  . ASP A 1 337 ? 128.856 127.099 101.092 1.00 84.88  ? 337 ASP B CA  1 
ATOM 786  C C   . ASP A 1 337 ? 127.395 127.484 101.283 1.00 84.87  ? 337 ASP B C   1 
ATOM 787  O O   . ASP A 1 337 ? 126.712 126.949 102.166 1.00 85.76  ? 337 ASP B O   1 
ATOM 788  C CB  . ASP A 1 337 ? 129.774 128.148 101.716 1.00 85.48  ? 337 ASP B CB  1 
ATOM 789  C CG  . ASP A 1 337 ? 131.228 127.724 101.709 1.00 88.57  ? 337 ASP B CG  1 
ATOM 790  O OD1 . ASP A 1 337 ? 131.514 126.591 101.269 1.00 88.31  ? 337 ASP B OD1 1 
ATOM 791  O OD2 . ASP A 1 337 ? 132.085 128.522 102.142 1.00 89.84  ? 337 ASP B OD2 1 
ATOM 792  N N   . ALA A 1 338 ? 126.897 128.413 100.464 1.00 78.27  ? 338 ALA B N   1 
ATOM 793  C CA  . ALA A 1 338 ? 125.511 128.845 100.603 1.00 75.75  ? 338 ALA B CA  1 
ATOM 794  C C   . ALA A 1 338 ? 124.542 127.692 100.371 1.00 73.62  ? 338 ALA B C   1 
ATOM 795  O O   . ALA A 1 338 ? 123.592 127.505 101.141 1.00 73.65  ? 338 ALA B O   1 
ATOM 796  C CB  . ALA A 1 338 ? 125.227 129.993 99.636  1.00 77.19  ? 338 ALA B CB  1 
ATOM 797  N N   . VAL A 1 339 ? 124.764 126.896 99.321  1.00 76.57  ? 339 VAL B N   1 
ATOM 798  C CA  . VAL A 1 339 ? 123.841 125.797 99.058  1.00 77.28  ? 339 VAL B CA  1 
ATOM 799  C C   . VAL A 1 339 ? 123.982 124.704 100.109 1.00 77.26  ? 339 VAL B C   1 
ATOM 800  O O   . VAL A 1 339 ? 123.002 124.028 100.434 1.00 76.44  ? 339 VAL B O   1 
ATOM 801  C CB  . VAL A 1 339 ? 124.030 125.235 97.637  1.00 76.18  ? 339 VAL B CB  1 
ATOM 802  C CG1 . VAL A 1 339 ? 125.375 124.535 97.494  1.00 76.42  ? 339 VAL B CG1 1 
ATOM 803  C CG2 . VAL A 1 339 ? 122.872 124.294 97.281  1.00 75.81  ? 339 VAL B CG2 1 
ATOM 804  N N   . THR A 1 340 ? 125.188 124.483 100.642 1.00 79.09  ? 340 THR B N   1 
ATOM 805  C CA  . THR A 1 340 ? 125.331 123.492 101.704 1.00 77.05  ? 340 THR B CA  1 
ATOM 806  C C   . THR A 1 340 ? 124.553 123.914 102.942 1.00 77.15  ? 340 THR B C   1 
ATOM 807  O O   . THR A 1 340 ? 123.871 123.093 103.570 1.00 77.40  ? 340 THR B O   1 
ATOM 808  C CB  . THR A 1 340 ? 126.806 123.281 102.039 1.00 76.86  ? 340 THR B CB  1 
ATOM 809  O OG1 . THR A 1 340 ? 127.457 124.549 102.174 1.00 78.31  ? 340 THR B OG1 1 
ATOM 810  C CG2 . THR A 1 340 ? 127.485 122.471 100.948 1.00 75.94  ? 340 THR B CG2 1 
ATOM 811  N N   . ASP A 1 341 ? 124.629 125.198 103.298 1.00 72.70  ? 341 ASP B N   1 
ATOM 812  C CA  . ASP A 1 341 ? 123.814 125.704 104.394 1.00 68.85  ? 341 ASP B CA  1 
ATOM 813  C C   . ASP A 1 341 ? 122.330 125.527 104.098 1.00 68.22  ? 341 ASP B C   1 
ATOM 814  O O   . ASP A 1 341 ? 121.562 125.091 104.964 1.00 71.87  ? 341 ASP B O   1 
ATOM 815  C CB  . ASP A 1 341 ? 124.136 127.176 104.642 1.00 72.47  ? 341 ASP B CB  1 
ATOM 816  C CG  . ASP A 1 341 ? 123.265 127.791 105.714 1.00 74.95  ? 341 ASP B CG  1 
ATOM 817  O OD1 . ASP A 1 341 ? 123.490 127.492 106.904 1.00 74.09  ? 341 ASP B OD1 1 
ATOM 818  O OD2 . ASP A 1 341 ? 122.357 128.575 105.368 1.00 74.68  ? 341 ASP B OD2 1 
ATOM 819  N N   . VAL A 1 342 ? 121.907 125.853 102.877 1.00 66.65  ? 342 VAL B N   1 
ATOM 820  C CA  . VAL A 1 342 ? 120.494 125.725 102.527 1.00 65.70  ? 342 VAL B CA  1 
ATOM 821  C C   . VAL A 1 342 ? 120.046 124.275 102.661 1.00 65.80  ? 342 VAL B C   1 
ATOM 822  O O   . VAL A 1 342 ? 118.958 123.990 103.175 1.00 67.11  ? 342 VAL B O   1 
ATOM 823  C CB  . VAL A 1 342 ? 120.248 126.273 101.108 1.00 67.31  ? 342 VAL B CB  1 
ATOM 824  C CG1 . VAL A 1 342 ? 118.874 125.869 100.599 1.00 66.32  ? 342 VAL B CG1 1 
ATOM 825  C CG2 . VAL A 1 342 ? 120.388 127.789 101.092 1.00 67.70  ? 342 VAL B CG2 1 
ATOM 826  N N   . ILE A 1 343 ? 120.875 123.337 102.202 1.00 69.31  ? 343 ILE B N   1 
ATOM 827  C CA  . ILE A 1 343 ? 120.519 121.923 102.265 1.00 69.97  ? 343 ILE B CA  1 
ATOM 828  C C   . ILE A 1 343 ? 120.434 121.456 103.711 1.00 70.89  ? 343 ILE B C   1 
ATOM 829  O O   . ILE A 1 343 ? 119.533 120.693 104.075 1.00 71.03  ? 343 ILE B O   1 
ATOM 830  C CB  . ILE A 1 343 ? 121.524 121.082 101.456 1.00 69.99  ? 343 ILE B CB  1 
ATOM 831  C CG1 . ILE A 1 343 ? 121.351 121.349 99.958  1.00 68.95  ? 343 ILE B CG1 1 
ATOM 832  C CG2 . ILE A 1 343 ? 121.352 119.596 101.771 1.00 69.06  ? 343 ILE B CG2 1 
ATOM 833  C CD1 . ILE A 1 343 ? 122.443 120.767 99.090  1.00 68.65  ? 343 ILE B CD1 1 
ATOM 834  N N   . ILE A 1 344 ? 121.375 121.885 104.554 1.00 69.89  ? 344 ILE B N   1 
ATOM 835  C CA  . ILE A 1 344 ? 121.335 121.480 105.958 1.00 66.71  ? 344 ILE B CA  1 
ATOM 836  C C   . ILE A 1 344 ? 120.073 122.010 106.626 1.00 62.33  ? 344 ILE B C   1 
ATOM 837  O O   . ILE A 1 344 ? 119.401 121.291 107.376 1.00 64.87  ? 344 ILE B O   1 
ATOM 838  C CB  . ILE A 1 344 ? 122.607 121.950 106.688 1.00 66.26  ? 344 ILE B CB  1 
ATOM 839  C CG1 . ILE A 1 344 ? 123.813 121.146 106.199 1.00 65.97  ? 344 ILE B CG1 1 
ATOM 840  C CG2 . ILE A 1 344 ? 122.441 121.820 108.198 1.00 63.68  ? 344 ILE B CG2 1 
ATOM 841  C CD1 . ILE A 1 344 ? 125.143 121.702 106.636 1.00 64.68  ? 344 ILE B CD1 1 
ATOM 842  N N   . LYS A 1 345 ? 119.732 123.275 106.372 1.00 65.38  ? 345 LYS B N   1 
ATOM 843  C CA  . LYS A 1 345 ? 118.528 123.839 106.976 1.00 67.30  ? 345 LYS B CA  1 
ATOM 844  C C   . LYS A 1 345 ? 117.274 123.139 106.462 1.00 66.96  ? 345 LYS B C   1 
ATOM 845  O O   . LYS A 1 345 ? 116.318 122.929 107.218 1.00 68.22  ? 345 LYS B O   1 
ATOM 846  C CB  . LYS A 1 345 ? 118.458 125.344 106.713 1.00 65.91  ? 345 LYS B CB  1 
ATOM 847  C CG  . LYS A 1 345 ? 119.222 126.217 107.714 1.00 66.71  ? 345 LYS B CG  1 
ATOM 848  C CD  . LYS A 1 345 ? 120.695 125.852 107.799 1.00 68.60  ? 345 LYS B CD  1 
ATOM 849  C CE  . LYS A 1 345 ? 121.460 126.712 108.786 1.00 69.37  ? 345 LYS B CE  1 
ATOM 850  N NZ  . LYS A 1 345 ? 122.803 126.117 109.051 1.00 69.60  ? 345 LYS B NZ  1 
ATOM 851  N N   . ASN A 1 346 ? 117.254 122.766 105.180 1.00 74.58  ? 346 ASN B N   1 
ATOM 852  C CA  . ASN A 1 346 ? 116.110 122.031 104.649 1.00 73.13  ? 346 ASN B CA  1 
ATOM 853  C C   . ASN A 1 346 ? 116.003 120.647 105.281 1.00 71.77  ? 346 ASN B C   1 
ATOM 854  O O   . ASN A 1 346 ? 114.897 120.172 105.563 1.00 72.88  ? 346 ASN B O   1 
ATOM 855  C CB  . ASN A 1 346 ? 116.216 121.922 103.128 1.00 74.06  ? 346 ASN B CB  1 
ATOM 856  C CG  . ASN A 1 346 ? 114.879 121.647 102.470 1.00 75.42  ? 346 ASN B CG  1 
ATOM 857  O OD1 . ASN A 1 346 ? 114.079 120.854 102.969 1.00 76.94  ? 346 ASN B OD1 1 
ATOM 858  N ND2 . ASN A 1 346 ? 114.625 122.307 101.346 1.00 74.86  ? 346 ASN B ND2 1 
ATOM 859  N N   . ASN A 1 347 ? 117.140 119.983 105.506 1.00 66.87  ? 347 ASN B N   1 
ATOM 860  C CA  . ASN A 1 347 ? 117.123 118.698 106.202 1.00 66.97  ? 347 ASN B CA  1 
ATOM 861  C C   . ASN A 1 347 ? 116.581 118.850 107.617 1.00 67.00  ? 347 ASN B C   1 
ATOM 862  O O   . ASN A 1 347 ? 115.760 118.042 108.069 1.00 65.46  ? 347 ASN B O   1 
ATOM 863  C CB  . ASN A 1 347 ? 118.530 118.100 106.237 1.00 65.82  ? 347 ASN B CB  1 
ATOM 864  C CG  . ASN A 1 347 ? 118.888 117.361 104.960 1.00 67.97  ? 347 ASN B CG  1 
ATOM 865  O OD1 . ASN A 1 347 ? 118.014 116.989 104.177 1.00 68.67  ? 347 ASN B OD1 1 
ATOM 866  N ND2 . ASN A 1 347 ? 120.180 117.133 104.751 1.00 66.56  ? 347 ASN B ND2 1 
ATOM 867  N N   . LEU A 1 348 ? 117.027 119.884 108.330 1.00 66.51  ? 348 LEU B N   1 
ATOM 868  C CA  . LEU A 1 348 ? 116.521 120.121 109.677 1.00 61.05  ? 348 LEU B CA  1 
ATOM 869  C C   . LEU A 1 348 ? 115.023 120.378 109.659 1.00 63.15  ? 348 LEU B C   1 
ATOM 870  O O   . LEU A 1 348 ? 114.291 119.894 110.528 1.00 68.58  ? 348 LEU B O   1 
ATOM 871  C CB  . LEU A 1 348 ? 117.251 121.296 110.314 1.00 61.37  ? 348 LEU B CB  1 
ATOM 872  C CG  . LEU A 1 348 ? 118.730 121.101 110.638 1.00 63.44  ? 348 LEU B CG  1 
ATOM 873  C CD1 . LEU A 1 348 ? 119.351 122.437 110.985 1.00 65.05  ? 348 LEU B CD1 1 
ATOM 874  C CD2 . LEU A 1 348 ? 118.943 120.104 111.767 1.00 64.70  ? 348 LEU B CD2 1 
ATOM 875  N N   . LYS A 1 349 ? 114.548 121.151 108.681 1.00 76.14  ? 349 LYS B N   1 
ATOM 876  C CA  . LYS A 1 349 ? 113.113 121.376 108.557 1.00 74.65  ? 349 LYS B CA  1 
ATOM 877  C C   . LYS A 1 349 ? 112.378 120.070 108.294 1.00 71.82  ? 349 LYS B C   1 
ATOM 878  O O   . LYS A 1 349 ? 111.280 119.849 108.818 1.00 70.64  ? 349 LYS B O   1 
ATOM 879  C CB  . LYS A 1 349 ? 112.833 122.378 107.438 1.00 75.37  ? 349 LYS B CB  1 
ATOM 880  C CG  . LYS A 1 349 ? 112.807 123.836 107.876 1.00 74.48  ? 349 LYS B CG  1 
ATOM 881  C CD  . LYS A 1 349 ? 112.873 124.777 106.677 1.00 76.09  ? 349 LYS B CD  1 
ATOM 882  C CE  . LYS A 1 349 ? 111.660 124.632 105.772 1.00 76.62  ? 349 LYS B CE  1 
ATOM 883  N NZ  . LYS A 1 349 ? 111.681 125.624 104.665 1.00 72.85  ? 349 LYS B NZ  1 
ATOM 884  N N   . ASP A 1 350 ? 112.966 119.195 107.478 1.00 76.48  ? 350 ASP B N   1 
ATOM 885  C CA  . ASP A 1 350 ? 112.341 117.907 107.204 1.00 77.11  ? 350 ASP B CA  1 
ATOM 886  C C   . ASP A 1 350 ? 112.246 117.065 108.470 1.00 79.42  ? 350 ASP B C   1 
ATOM 887  O O   . ASP A 1 350 ? 111.237 116.389 108.701 1.00 80.08  ? 350 ASP B O   1 
ATOM 888  C CB  . ASP A 1 350 ? 113.125 117.163 106.124 1.00 77.84  ? 350 ASP B CB  1 
ATOM 889  C CG  . ASP A 1 350 ? 113.114 117.888 104.792 1.00 79.39  ? 350 ASP B CG  1 
ATOM 890  O OD1 . ASP A 1 350 ? 112.038 118.379 104.389 1.00 80.21  ? 350 ASP B OD1 1 
ATOM 891  O OD2 . ASP A 1 350 ? 114.182 117.971 104.151 1.00 76.95  ? 350 ASP B OD2 1 
ATOM 892  N N   . CYS A 1 351 ? 113.283 117.098 109.308 1.00 74.47  ? 351 CYS B N   1 
ATOM 893  C CA  . CYS A 1 351 ? 113.290 116.302 110.530 1.00 71.82  ? 351 CYS B CA  1 
ATOM 894  C C   . CYS A 1 351 ? 112.565 116.982 111.687 1.00 71.62  ? 351 CYS B C   1 
ATOM 895  O O   . CYS A 1 351 ? 112.549 116.430 112.791 1.00 72.29  ? 351 CYS B O   1 
ATOM 896  C CB  . CYS A 1 351 ? 114.731 115.977 110.941 1.00 70.88  ? 351 CYS B CB  1 
ATOM 897  S SG  . CYS A 1 351 ? 115.562 117.273 111.879 1.00 70.54  ? 351 CYS B SG  1 
ATOM 898  N N   . GLY A 1 352 ? 111.980 118.160 111.472 1.00 67.86  ? 352 GLY B N   1 
ATOM 899  C CA  . GLY A 1 352 ? 111.153 118.801 112.472 1.00 65.31  ? 352 GLY B CA  1 
ATOM 900  C C   . GLY A 1 352 ? 111.898 119.594 113.519 1.00 65.31  ? 352 GLY B C   1 
ATOM 901  O O   . GLY A 1 352 ? 111.253 120.268 114.330 1.00 69.63  ? 352 GLY B O   1 
ATOM 902  N N   . LEU A 1 353 ? 113.229 119.532 113.544 1.00 66.73  ? 353 LEU B N   1 
ATOM 903  C CA  . LEU A 1 353 ? 113.983 120.229 114.576 1.00 70.35  ? 353 LEU B CA  1 
ATOM 904  C C   . LEU A 1 353 ? 113.949 121.744 114.407 1.00 75.10  ? 353 LEU B C   1 
ATOM 905  O O   . LEU A 1 353 ? 114.287 122.465 115.353 1.00 77.14  ? 353 LEU B O   1 
ATOM 906  C CB  . LEU A 1 353 ? 115.430 119.733 114.583 1.00 69.30  ? 353 LEU B CB  1 
ATOM 907  C CG  . LEU A 1 353 ? 116.361 120.190 115.709 1.00 68.79  ? 353 LEU B CG  1 
ATOM 908  C CD1 . LEU A 1 353 ? 115.766 119.905 117.076 1.00 68.19  ? 353 LEU B CD1 1 
ATOM 909  C CD2 . LEU A 1 353 ? 117.709 119.507 115.569 1.00 68.40  ? 353 LEU B CD2 1 
ATOM 910  N N   . PHE A 1 354 ? 113.549 122.249 113.244 1.00 82.12  ? 354 PHE B N   1 
ATOM 911  C CA  . PHE A 1 354 ? 113.487 123.701 113.062 1.00 81.36  ? 354 PHE B CA  1 
ATOM 912  C C   . PHE A 1 354 ? 112.223 124.276 113.697 1.00 83.06  ? 354 PHE B C   1 
ATOM 913  O O   . PHE A 1 354 ? 112.068 125.494 113.819 1.00 84.26  ? 354 PHE B O   1 
ATOM 914  C CB  . PHE A 1 354 ? 113.542 124.083 111.576 1.00 83.40  ? 354 PHE B CB  1 
ATOM 915  C CG  . PHE A 1 354 ? 114.187 125.425 111.331 1.00 84.29  ? 354 PHE B CG  1 
ATOM 916  C CD1 . PHE A 1 354 ? 115.556 125.524 111.205 1.00 82.52  ? 354 PHE B CD1 1 
ATOM 917  C CD2 . PHE A 1 354 ? 113.438 126.587 111.248 1.00 84.42  ? 354 PHE B CD2 1 
ATOM 918  C CE1 . PHE A 1 354 ? 116.165 126.739 110.992 1.00 83.79  ? 354 PHE B CE1 1 
ATOM 919  C CE2 . PHE A 1 354 ? 114.054 127.814 111.029 1.00 84.55  ? 354 PHE B CE2 1 
ATOM 920  C CZ  . PHE A 1 354 ? 115.417 127.881 110.901 1.00 84.93  ? 354 PHE B CZ  1 
ATOM 921  N N   . THR B 2 34  ? 67.659  132.461 81.422  1.00 99.24  ? 29  THR C N   1 
ATOM 922  C CA  . THR B 2 34  ? 69.071  132.129 81.768  1.00 99.70  ? 29  THR C CA  1 
ATOM 923  C C   . THR B 2 34  ? 69.168  130.712 82.325  1.00 99.68  ? 29  THR C C   1 
ATOM 924  O O   . THR B 2 34  ? 68.158  130.033 82.500  1.00 98.76  ? 29  THR C O   1 
ATOM 925  C CB  . THR B 2 34  ? 69.650  133.118 82.797  1.00 99.09  ? 29  THR C CB  1 
ATOM 926  O OG1 . THR B 2 34  ? 68.939  133.001 84.034  1.00 97.17  ? 29  THR C OG1 1 
ATOM 927  C CG2 . THR B 2 34  ? 69.545  134.546 82.286  1.00 97.77  ? 29  THR C CG2 1 
ATOM 928  N N   . LEU B 2 35  ? 70.399  130.271 82.595  1.00 93.60  ? 30  LEU C N   1 
ATOM 929  C CA  . LEU B 2 35  ? 70.604  128.922 83.110  1.00 92.31  ? 30  LEU C CA  1 
ATOM 930  C C   . LEU B 2 35  ? 70.099  128.793 84.543  1.00 93.47  ? 30  LEU C C   1 
ATOM 931  O O   . LEU B 2 35  ? 69.483  127.782 84.902  1.00 93.66  ? 30  LEU C O   1 
ATOM 932  C CB  . LEU B 2 35  ? 72.086  128.558 83.029  1.00 90.87  ? 30  LEU C CB  1 
ATOM 933  C CG  . LEU B 2 35  ? 72.430  127.069 83.103  1.00 93.02  ? 30  LEU C CG  1 
ATOM 934  C CD1 . LEU B 2 35  ? 71.955  126.345 81.855  1.00 93.29  ? 30  LEU C CD1 1 
ATOM 935  C CD2 . LEU B 2 35  ? 73.926  126.871 83.303  1.00 91.11  ? 30  LEU C CD2 1 
ATOM 936  N N   . SER B 2 36  ? 70.350  129.807 85.376  1.00 96.25  ? 31  SER C N   1 
ATOM 937  C CA  . SER B 2 36  ? 69.953  129.732 86.778  1.00 95.40  ? 31  SER C CA  1 
ATOM 938  C C   . SER B 2 36  ? 68.440  129.629 86.922  1.00 96.48  ? 31  SER C C   1 
ATOM 939  O O   . SER B 2 36  ? 67.938  128.876 87.765  1.00 96.28  ? 31  SER C O   1 
ATOM 940  C CB  . SER B 2 36  ? 70.480  130.949 87.535  1.00 95.48  ? 31  SER C CB  1 
ATOM 941  O OG  . SER B 2 36  ? 70.126  130.889 88.905  1.00 95.12  ? 31  SER C OG  1 
ATOM 942  N N   . GLN B 2 37  ? 67.694  130.385 86.114  1.00 99.90  ? 32  GLN C N   1 
ATOM 943  C CA  . GLN B 2 37  ? 66.239  130.352 86.216  1.00 100.68 ? 32  GLN C CA  1 
ATOM 944  C C   . GLN B 2 37  ? 65.698  128.962 85.905  1.00 101.11 ? 32  GLN C C   1 
ATOM 945  O O   . GLN B 2 37  ? 64.791  128.473 86.589  1.00 100.70 ? 32  GLN C O   1 
ATOM 946  C CB  . GLN B 2 37  ? 65.628  131.389 85.274  1.00 100.37 ? 32  GLN C CB  1 
ATOM 947  C CG  . GLN B 2 37  ? 66.026  132.821 85.590  1.00 100.73 ? 32  GLN C CG  1 
ATOM 948  C CD  . GLN B 2 37  ? 65.476  133.811 84.586  1.00 101.31 ? 32  GLN C CD  1 
ATOM 949  O OE1 . GLN B 2 37  ? 64.810  133.432 83.624  1.00 99.80  ? 32  GLN C OE1 1 
ATOM 950  N NE2 . GLN B 2 37  ? 65.754  135.091 84.805  1.00 100.94 ? 32  GLN C NE2 1 
ATOM 951  N N   . ILE B 2 38  ? 66.241  128.310 84.877  1.00 98.00  ? 33  ILE C N   1 
ATOM 952  C CA  . ILE B 2 38  ? 65.784  126.970 84.523  1.00 98.05  ? 33  ILE C CA  1 
ATOM 953  C C   . ILE B 2 38  ? 66.215  125.961 85.580  1.00 97.80  ? 33  ILE C C   1 
ATOM 954  O O   . ILE B 2 38  ? 65.461  125.044 85.926  1.00 97.40  ? 33  ILE C O   1 
ATOM 955  C CB  . ILE B 2 38  ? 66.302  126.588 83.123  1.00 97.38  ? 33  ILE C CB  1 
ATOM 956  C CG1 . ILE B 2 38  ? 65.789  127.588 82.081  1.00 97.71  ? 33  ILE C CG1 1 
ATOM 957  C CG2 . ILE B 2 38  ? 65.873  125.166 82.754  1.00 96.19  ? 33  ILE C CG2 1 
ATOM 958  C CD1 . ILE B 2 38  ? 66.291  127.337 80.674  1.00 97.62  ? 33  ILE C CD1 1 
ATOM 959  N N   . THR B 2 39  ? 67.428  126.109 86.111  1.00 97.81  ? 34  THR C N   1 
ATOM 960  C CA  . THR B 2 39  ? 67.976  125.142 87.053  1.00 97.03  ? 34  THR C CA  1 
ATOM 961  C C   . THR B 2 39  ? 67.489  125.347 88.483  1.00 97.17  ? 34  THR C C   1 
ATOM 962  O O   . THR B 2 39  ? 67.798  124.517 89.345  1.00 96.53  ? 34  THR C O   1 
ATOM 963  C CB  . THR B 2 39  ? 69.506  125.198 87.025  1.00 96.13  ? 34  THR C CB  1 
ATOM 964  O OG1 . THR B 2 39  ? 69.942  126.537 87.282  1.00 96.85  ? 34  THR C OG1 1 
ATOM 965  C CG2 . THR B 2 39  ? 70.031  124.743 85.672  1.00 95.27  ? 34  THR C CG2 1 
ATOM 966  N N   . ASN B 2 40  ? 66.746  126.422 88.759  1.00 98.61  ? 35  ASN C N   1 
ATOM 967  C CA  . ASN B 2 40  ? 66.231  126.629 90.110  1.00 98.67  ? 35  ASN C CA  1 
ATOM 968  C C   . ASN B 2 40  ? 65.365  125.461 90.565  1.00 98.97  ? 35  ASN C C   1 
ATOM 969  O O   . ASN B 2 40  ? 65.493  124.993 91.703  1.00 97.99  ? 35  ASN C O   1 
ATOM 970  C CB  . ASN B 2 40  ? 65.433  127.932 90.173  1.00 97.80  ? 35  ASN C CB  1 
ATOM 971  C CG  . ASN B 2 40  ? 66.302  129.136 90.474  1.00 98.29  ? 35  ASN C CG  1 
ATOM 972  O OD1 . ASN B 2 40  ? 67.528  129.076 90.367  1.00 98.42  ? 35  ASN C OD1 1 
ATOM 973  N ND2 . ASN B 2 40  ? 65.670  130.238 90.858  1.00 98.15  ? 35  ASN C ND2 1 
ATOM 974  N N   . ASN B 2 41  ? 64.478  124.975 89.697  1.00 99.07  ? 36  ASN C N   1 
ATOM 975  C CA  . ASN B 2 41  ? 63.585  123.885 90.066  1.00 98.35  ? 36  ASN C CA  1 
ATOM 976  C C   . ASN B 2 41  ? 64.289  122.537 90.135  1.00 97.15  ? 36  ASN C C   1 
ATOM 977  O O   . ASN B 2 41  ? 63.716  121.585 90.676  1.00 96.27  ? 36  ASN C O   1 
ATOM 978  C CB  . ASN B 2 41  ? 62.425  123.796 89.073  1.00 98.26  ? 36  ASN C CB  1 
ATOM 979  C CG  . ASN B 2 41  ? 62.792  123.037 87.815  1.00 98.44  ? 36  ASN C CG  1 
ATOM 980  O OD1 . ASN B 2 41  ? 63.885  123.201 87.272  1.00 98.32  ? 36  ASN C OD1 1 
ATOM 981  N ND2 . ASN B 2 41  ? 61.880  122.194 87.347  1.00 97.75  ? 36  ASN C ND2 1 
ATOM 982  N N   . ILE B 2 42  ? 65.507  122.430 89.604  1.00 93.29  ? 37  ILE C N   1 
ATOM 983  C CA  . ILE B 2 42  ? 66.228  121.164 89.622  1.00 93.47  ? 37  ILE C CA  1 
ATOM 984  C C   . ILE B 2 42  ? 66.693  120.870 91.041  1.00 92.62  ? 37  ILE C C   1 
ATOM 985  O O   . ILE B 2 42  ? 67.248  121.741 91.724  1.00 92.08  ? 37  ILE C O   1 
ATOM 986  C CB  . ILE B 2 42  ? 67.412  121.205 88.644  1.00 92.69  ? 37  ILE C CB  1 
ATOM 987  C CG1 . ILE B 2 42  ? 66.932  121.515 87.221  1.00 92.53  ? 37  ILE C CG1 1 
ATOM 988  C CG2 . ILE B 2 42  ? 68.177  119.892 88.674  1.00 91.44  ? 37  ILE C CG2 1 
ATOM 989  C CD1 . ILE B 2 42  ? 65.988  120.482 86.633  1.00 92.81  ? 37  ILE C CD1 1 
ATOM 990  N N   . ASP B 2 43  ? 66.464  119.641 91.492  1.00 88.04  ? 38  ASP C N   1 
ATOM 991  C CA  . ASP B 2 43  ? 66.889  119.253 92.825  1.00 88.17  ? 38  ASP C CA  1 
ATOM 992  C C   . ASP B 2 43  ? 68.416  119.241 92.911  1.00 88.90  ? 38  ASP C C   1 
ATOM 993  O O   . ASP B 2 43  ? 69.099  118.960 91.923  1.00 87.53  ? 38  ASP C O   1 
ATOM 994  C CB  . ASP B 2 43  ? 66.338  117.875 93.186  1.00 87.71  ? 38  ASP C CB  1 
ATOM 995  C CG  . ASP B 2 43  ? 66.633  116.830 92.127  1.00 88.57  ? 38  ASP C CG  1 
ATOM 996  O OD1 . ASP B 2 43  ? 67.296  117.166 91.123  1.00 88.22  ? 38  ASP C OD1 1 
ATOM 997  O OD2 . ASP B 2 43  ? 66.198  115.672 92.298  1.00 87.62  ? 38  ASP C OD2 1 
ATOM 998  N N   . PRO B 2 44  ? 68.979  119.544 94.085  1.00 84.85  ? 39  PRO C N   1 
ATOM 999  C CA  . PRO B 2 44  ? 70.441  119.608 94.200  1.00 81.58  ? 39  PRO C CA  1 
ATOM 1000 C C   . PRO B 2 44  ? 71.091  118.235 94.181  1.00 80.69  ? 39  PRO C C   1 
ATOM 1001 O O   . PRO B 2 44  ? 70.416  117.219 93.990  1.00 80.71  ? 39  PRO C O   1 
ATOM 1002 C CB  . PRO B 2 44  ? 70.652  120.312 95.545  1.00 80.41  ? 39  PRO C CB  1 
ATOM 1003 C CG  . PRO B 2 44  ? 69.453  119.962 96.336  1.00 81.75  ? 39  PRO C CG  1 
ATOM 1004 C CD  . PRO B 2 44  ? 68.315  119.866 95.359  1.00 82.05  ? 39  PRO C CD  1 
ATOM 1005 N N   . VAL B 2 45  ? 72.405  118.201 94.376  1.00 71.82  ? 40  VAL C N   1 
ATOM 1006 C CA  . VAL B 2 45  ? 73.159  116.951 94.352  1.00 71.40  ? 40  VAL C CA  1 
ATOM 1007 C C   . VAL B 2 45  ? 73.307  116.365 95.749  1.00 70.14  ? 40  VAL C C   1 
ATOM 1008 O O   . VAL B 2 45  ? 73.071  115.174 95.964  1.00 67.99  ? 40  VAL C O   1 
ATOM 1009 C CB  . VAL B 2 45  ? 74.537  117.189 93.696  1.00 70.34  ? 40  VAL C CB  1 
ATOM 1010 C CG1 . VAL B 2 45  ? 75.458  116.003 93.938  1.00 71.17  ? 40  VAL C CG1 1 
ATOM 1011 C CG2 . VAL B 2 45  ? 74.377  117.457 92.209  1.00 68.53  ? 40  VAL C CG2 1 
ATOM 1012 N N   . GLY B 2 46  ? 73.698  117.188 96.714  1.00 66.46  ? 41  GLY C N   1 
ATOM 1013 C CA  . GLY B 2 46  ? 74.043  116.728 98.041  1.00 67.13  ? 41  GLY C CA  1 
ATOM 1014 C C   . GLY B 2 46  ? 75.547  116.661 98.236  1.00 67.57  ? 41  GLY C C   1 
ATOM 1015 O O   . GLY B 2 46  ? 76.341  116.784 97.300  1.00 69.60  ? 41  GLY C O   1 
ATOM 1016 N N   . ARG B 2 47  ? 75.942  116.455 99.489  1.00 62.78  ? 42  ARG C N   1 
ATOM 1017 C CA  . ARG B 2 47  ? 77.358  116.477 99.823  1.00 62.47  ? 42  ARG C CA  1 
ATOM 1018 C C   . ARG B 2 47  ? 78.081  115.308 99.167  1.00 61.58  ? 42  ARG C C   1 
ATOM 1019 O O   . ARG B 2 47  ? 77.577  114.182 99.134  1.00 64.44  ? 42  ARG C O   1 
ATOM 1020 C CB  . ARG B 2 47  ? 77.551  116.437 101.338 1.00 61.62  ? 42  ARG C CB  1 
ATOM 1021 C CG  . ARG B 2 47  ? 78.893  116.990 101.804 1.00 62.04  ? 42  ARG C CG  1 
ATOM 1022 C CD  . ARG B 2 47  ? 78.977  118.502 101.611 1.00 62.98  ? 42  ARG C CD  1 
ATOM 1023 N NE  . ARG B 2 47  ? 80.308  119.029 101.889 1.00 64.45  ? 42  ARG C NE  1 
ATOM 1024 C CZ  . ARG B 2 47  ? 80.715  120.248 101.562 1.00 63.77  ? 42  ARG C CZ  1 
ATOM 1025 N NH1 . ARG B 2 47  ? 79.924  121.096 100.924 1.00 60.00  ? 42  ARG C NH1 1 
ATOM 1026 N NH2 . ARG B 2 47  ? 81.950  120.626 101.880 1.00 63.00  ? 42  ARG C NH2 1 
ATOM 1027 N N   . ILE B 2 48  ? 79.271  115.585 98.639  1.00 51.48  ? 43  ILE C N   1 
ATOM 1028 C CA  . ILE B 2 48  ? 80.080  114.605 97.923  1.00 51.68  ? 43  ILE C CA  1 
ATOM 1029 C C   . ILE B 2 48  ? 81.236  114.203 98.825  1.00 52.82  ? 43  ILE C C   1 
ATOM 1030 O O   . ILE B 2 48  ? 82.053  115.046 99.213  1.00 53.08  ? 43  ILE C O   1 
ATOM 1031 C CB  . ILE B 2 48  ? 80.591  115.167 96.586  1.00 51.24  ? 43  ILE C CB  1 
ATOM 1032 C CG1 . ILE B 2 48  ? 79.448  115.281 95.570  1.00 50.96  ? 43  ILE C CG1 1 
ATOM 1033 C CG2 . ILE B 2 48  ? 81.728  114.318 96.041  1.00 43.57  ? 43  ILE C CG2 1 
ATOM 1034 C CD1 . ILE B 2 48  ? 78.910  113.961 95.068  1.00 48.36  ? 43  ILE C CD1 1 
ATOM 1035 N N   . GLN B 2 49  ? 81.309  112.916 99.151  1.00 52.74  ? 44  GLN C N   1 
ATOM 1036 C CA  . GLN B 2 49  ? 82.356  112.378 100.008 1.00 50.67  ? 44  GLN C CA  1 
ATOM 1037 C C   . GLN B 2 49  ? 83.053  111.235 99.289  1.00 49.16  ? 44  GLN C C   1 
ATOM 1038 O O   . GLN B 2 49  ? 82.397  110.297 98.826  1.00 51.48  ? 44  GLN C O   1 
ATOM 1039 C CB  . GLN B 2 49  ? 81.778  111.896 101.342 1.00 50.13  ? 44  GLN C CB  1 
ATOM 1040 C CG  . GLN B 2 49  ? 81.415  113.022 102.300 1.00 52.75  ? 44  GLN C CG  1 
ATOM 1041 C CD  . GLN B 2 49  ? 80.393  112.605 103.339 1.00 54.81  ? 44  GLN C CD  1 
ATOM 1042 O OE1 . GLN B 2 49  ? 79.487  111.822 103.058 1.00 53.34  ? 44  GLN C OE1 1 
ATOM 1043 N NE2 . GLN B 2 49  ? 80.536  113.131 104.550 1.00 54.12  ? 44  GLN C NE2 1 
ATOM 1044 N N   . MET B 2 50  ? 84.377  111.320 99.193  1.00 36.37  ? 45  MET C N   1 
ATOM 1045 C CA  . MET B 2 50  ? 85.174  110.251 98.613  1.00 39.27  ? 45  MET C CA  1 
ATOM 1046 C C   . MET B 2 50  ? 86.522  110.220 99.316  1.00 42.11  ? 45  MET C C   1 
ATOM 1047 O O   . MET B 2 50  ? 86.974  111.220 99.877  1.00 42.02  ? 45  MET C O   1 
ATOM 1048 C CB  . MET B 2 50  ? 85.347  110.430 97.100  1.00 38.13  ? 45  MET C CB  1 
ATOM 1049 C CG  . MET B 2 50  ? 86.049  111.711 96.684  1.00 31.28  ? 45  MET C CG  1 
ATOM 1050 S SD  . MET B 2 50  ? 86.207  111.869 94.895  1.00 39.58  ? 45  MET C SD  1 
ATOM 1051 C CE  . MET B 2 50  ? 84.490  112.016 94.408  1.00 36.90  ? 45  MET C CE  1 
ATOM 1052 N N   . ARG B 2 51  ? 87.159  109.051 99.283  1.00 31.98  ? 46  ARG C N   1 
ATOM 1053 C CA  . ARG B 2 51  ? 88.386  108.810 100.024 1.00 36.42  ? 46  ARG C CA  1 
ATOM 1054 C C   . ARG B 2 51  ? 89.455  108.245 99.102  1.00 26.68  ? 46  ARG C C   1 
ATOM 1055 O O   . ARG B 2 51  ? 89.163  107.696 98.038  1.00 22.14  ? 46  ARG C O   1 
ATOM 1056 C CB  . ARG B 2 51  ? 88.157  107.843 101.194 1.00 34.88  ? 46  ARG C CB  1 
ATOM 1057 C CG  . ARG B 2 51  ? 87.243  108.388 102.271 1.00 38.05  ? 46  ARG C CG  1 
ATOM 1058 C CD  . ARG B 2 51  ? 87.568  107.797 103.629 1.00 38.49  ? 46  ARG C CD  1 
ATOM 1059 N NE  . ARG B 2 51  ? 86.984  108.580 104.711 1.00 36.40  ? 46  ARG C NE  1 
ATOM 1060 C CZ  . ARG B 2 51  ? 87.363  108.507 105.980 1.00 38.70  ? 46  ARG C CZ  1 
ATOM 1061 N NH1 . ARG B 2 51  ? 88.327  107.689 106.368 1.00 36.29  ? 46  ARG C NH1 1 
ATOM 1062 N NH2 . ARG B 2 51  ? 86.761  109.277 106.881 1.00 34.85  ? 46  ARG C NH2 1 
ATOM 1063 N N   . THR B 2 52  ? 90.703  108.382 99.536  1.00 14.74  ? 47  THR C N   1 
ATOM 1064 C CA  . THR B 2 52  ? 91.845  107.860 98.794  1.00 23.11  ? 47  THR C CA  1 
ATOM 1065 C C   . THR B 2 52  ? 91.845  106.343 98.892  1.00 35.52  ? 47  THR C C   1 
ATOM 1066 O O   . THR B 2 52  ? 92.275  105.771 99.896  1.00 34.18  ? 47  THR C O   1 
ATOM 1067 C CB  . THR B 2 52  ? 93.148  108.428 99.341  1.00 24.36  ? 47  THR C CB  1 
ATOM 1068 O OG1 . THR B 2 52  ? 93.321  108.003 100.696 1.00 35.17  ? 47  THR C OG1 1 
ATOM 1069 C CG2 . THR B 2 52  ? 93.138  109.928 99.290  1.00 28.03  ? 47  THR C CG2 1 
ATOM 1070 N N   . ARG B 2 53  ? 91.357  105.680 97.844  1.00 38.94  ? 48  ARG C N   1 
ATOM 1071 C CA  . ARG B 2 53  ? 91.426  104.226 97.796  1.00 17.47  ? 48  ARG C CA  1 
ATOM 1072 C C   . ARG B 2 53  ? 92.857  103.747 97.597  1.00 26.33  ? 48  ARG C C   1 
ATOM 1073 O O   . ARG B 2 53  ? 93.269  102.747 98.193  1.00 38.92  ? 48  ARG C O   1 
ATOM 1074 C CB  . ARG B 2 53  ? 90.534  103.704 96.681  1.00 18.24  ? 48  ARG C CB  1 
ATOM 1075 C CG  . ARG B 2 53  ? 89.072  104.046 96.863  1.00 25.65  ? 48  ARG C CG  1 
ATOM 1076 C CD  . ARG B 2 53  ? 88.502  103.388 98.101  1.00 31.97  ? 48  ARG C CD  1 
ATOM 1077 N NE  . ARG B 2 53  ? 87.048  103.273 98.030  1.00 36.55  ? 48  ARG C NE  1 
ATOM 1078 C CZ  . ARG B 2 53  ? 86.180  103.963 98.759  1.00 36.46  ? 48  ARG C CZ  1 
ATOM 1079 N NH1 . ARG B 2 53  ? 86.572  104.824 99.685  1.00 33.83  ? 48  ARG C NH1 1 
ATOM 1080 N NH2 . ARG B 2 53  ? 84.878  103.780 98.556  1.00 32.32  ? 48  ARG C NH2 1 
ATOM 1081 N N   . ARG B 2 54  ? 93.626  104.440 96.764  1.00 22.96  ? 49  ARG C N   1 
ATOM 1082 C CA  . ARG B 2 54  ? 94.991  104.051 96.450  1.00 24.28  ? 49  ARG C CA  1 
ATOM 1083 C C   . ARG B 2 54  ? 95.930  105.223 96.687  1.00 29.06  ? 49  ARG C C   1 
ATOM 1084 O O   . ARG B 2 54  ? 95.524  106.387 96.671  1.00 22.55  ? 49  ARG C O   1 
ATOM 1085 C CB  . ARG B 2 54  ? 95.125  103.587 94.994  1.00 20.33  ? 49  ARG C CB  1 
ATOM 1086 C CG  . ARG B 2 54  ? 94.322  102.353 94.631  1.00 21.88  ? 49  ARG C CG  1 
ATOM 1087 C CD  . ARG B 2 54  ? 94.975  101.097 95.162  1.00 29.25  ? 49  ARG C CD  1 
ATOM 1088 N NE  . ARG B 2 54  ? 94.328  99.894  94.659  1.00 29.69  ? 49  ARG C NE  1 
ATOM 1089 C CZ  . ARG B 2 54  ? 93.235  99.353  95.177  1.00 29.86  ? 49  ARG C CZ  1 
ATOM 1090 N NH1 . ARG B 2 54  ? 92.629  99.887  96.223  1.00 27.36  ? 49  ARG C NH1 1 
ATOM 1091 N NH2 . ARG B 2 54  ? 92.736  98.251  94.627  1.00 29.21  ? 49  ARG C NH2 1 
ATOM 1092 N N   . THR B 2 55  ? 97.201  104.896 96.908  1.00 27.22  ? 50  THR C N   1 
ATOM 1093 C CA  . THR B 2 55  ? 98.264  105.891 96.980  1.00 23.19  ? 50  THR C CA  1 
ATOM 1094 C C   . THR B 2 55  ? 99.486  105.324 96.279  1.00 26.16  ? 50  THR C C   1 
ATOM 1095 O O   . THR B 2 55  ? 100.048 104.321 96.728  1.00 35.12  ? 50  THR C O   1 
ATOM 1096 C CB  . THR B 2 55  ? 98.602  106.260 98.427  1.00 22.59  ? 50  THR C CB  1 
ATOM 1097 O OG1 . THR B 2 55  ? 97.466  106.875 99.044  1.00 31.72  ? 50  THR C OG1 1 
ATOM 1098 C CG2 . THR B 2 55  ? 99.779  107.223 98.476  1.00 24.86  ? 50  THR C CG2 1 
ATOM 1099 N N   . LEU B 2 56  ? 99.897  105.967 95.190  1.00 23.86  ? 51  LEU C N   1 
ATOM 1100 C CA  . LEU B 2 56  ? 101.015 105.515 94.373  1.00 19.72  ? 51  LEU C CA  1 
ATOM 1101 C C   . LEU B 2 56  ? 102.251 106.318 94.746  1.00 23.15  ? 51  LEU C C   1 
ATOM 1102 O O   . LEU B 2 56  ? 102.277 107.540 94.572  1.00 28.84  ? 51  LEU C O   1 
ATOM 1103 C CB  . LEU B 2 56  ? 100.695 105.674 92.889  1.00 22.83  ? 51  LEU C CB  1 
ATOM 1104 C CG  . LEU B 2 56  ? 99.322  105.168 92.447  1.00 22.93  ? 51  LEU C CG  1 
ATOM 1105 C CD1 . LEU B 2 56  ? 99.167  105.301 90.942  1.00 14.66  ? 51  LEU C CD1 1 
ATOM 1106 C CD2 . LEU B 2 56  ? 99.116  103.728 92.892  1.00 35.76  ? 51  LEU C CD2 1 
ATOM 1107 N N   . ARG B 2 57  ? 103.275 105.632 95.247  1.00 28.23  ? 52  ARG C N   1 
ATOM 1108 C CA  . ARG B 2 57  ? 104.472 106.266 95.792  1.00 27.08  ? 52  ARG C CA  1 
ATOM 1109 C C   . ARG B 2 57  ? 105.688 105.721 95.051  1.00 28.11  ? 52  ARG C C   1 
ATOM 1110 O O   . ARG B 2 57  ? 106.375 104.826 95.543  1.00 34.41  ? 52  ARG C O   1 
ATOM 1111 C CB  . ARG B 2 57  ? 104.583 106.005 97.292  1.00 31.83  ? 52  ARG C CB  1 
ATOM 1112 C CG  . ARG B 2 57  ? 103.301 106.218 98.078  1.00 28.52  ? 52  ARG C CG  1 
ATOM 1113 C CD  . ARG B 2 57  ? 103.456 105.729 99.505  1.00 37.33  ? 52  ARG C CD  1 
ATOM 1114 N NE  . ARG B 2 57  ? 103.464 104.272 99.584  1.00 39.70  ? 52  ARG C NE  1 
ATOM 1115 C CZ  . ARG B 2 57  ? 102.431 103.519 99.942  1.00 39.25  ? 52  ARG C CZ  1 
ATOM 1116 N NH1 . ARG B 2 57  ? 101.268 104.050 100.287 1.00 34.59  ? 52  ARG C NH1 1 
ATOM 1117 N NH2 . ARG B 2 57  ? 102.569 102.197 99.960  1.00 37.97  ? 52  ARG C NH2 1 
ATOM 1118 N N   . GLY B 2 58  ? 105.955 106.262 93.869  1.00 24.69  ? 53  GLY C N   1 
ATOM 1119 C CA  . GLY B 2 58  ? 107.150 105.901 93.135  1.00 16.80  ? 53  GLY C CA  1 
ATOM 1120 C C   . GLY B 2 58  ? 107.795 107.081 92.442  1.00 25.59  ? 53  GLY C C   1 
ATOM 1121 O O   . GLY B 2 58  ? 108.540 106.902 91.475  1.00 34.49  ? 53  GLY C O   1 
ATOM 1122 N N   . HIS B 2 59  ? 107.529 108.288 92.932  1.00 33.17  ? 54  HIS C N   1 
ATOM 1123 C CA  . HIS B 2 59  ? 108.109 109.504 92.385  1.00 25.20  ? 54  HIS C CA  1 
ATOM 1124 C C   . HIS B 2 59  ? 108.777 110.268 93.517  1.00 28.55  ? 54  HIS C C   1 
ATOM 1125 O O   . HIS B 2 59  ? 108.409 110.132 94.686  1.00 33.80  ? 54  HIS C O   1 
ATOM 1126 C CB  . HIS B 2 59  ? 107.059 110.395 91.696  1.00 26.82  ? 54  HIS C CB  1 
ATOM 1127 C CG  . HIS B 2 59  ? 106.779 110.024 90.270  1.00 34.13  ? 54  HIS C CG  1 
ATOM 1128 N ND1 . HIS B 2 59  ? 107.771 109.920 89.319  1.00 24.40  ? 54  HIS C ND1 1 
ATOM 1129 C CD2 . HIS B 2 59  ? 105.616 109.759 89.629  1.00 24.36  ? 54  HIS C CD2 1 
ATOM 1130 C CE1 . HIS B 2 59  ? 107.232 109.593 88.158  1.00 14.93  ? 54  HIS C CE1 1 
ATOM 1131 N NE2 . HIS B 2 59  ? 105.926 109.491 88.318  1.00 11.84  ? 54  HIS C NE2 1 
ATOM 1132 N N   . LEU B 2 60  ? 109.772 111.078 93.158  1.00 34.65  ? 55  LEU C N   1 
ATOM 1133 C CA  . LEU B 2 60  ? 110.575 111.787 94.142  1.00 40.88  ? 55  LEU C CA  1 
ATOM 1134 C C   . LEU B 2 60  ? 110.609 113.296 93.937  1.00 42.41  ? 55  LEU C C   1 
ATOM 1135 O O   . LEU B 2 60  ? 111.366 113.977 94.635  1.00 45.34  ? 55  LEU C O   1 
ATOM 1136 C CB  . LEU B 2 60  ? 112.013 111.246 94.140  1.00 41.63  ? 55  LEU C CB  1 
ATOM 1137 C CG  . LEU B 2 60  ? 112.159 109.741 94.384  1.00 45.07  ? 55  LEU C CG  1 
ATOM 1138 C CD1 . LEU B 2 60  ? 113.613 109.322 94.257  1.00 41.29  ? 55  LEU C CD1 1 
ATOM 1139 C CD2 . LEU B 2 60  ? 111.607 109.352 95.749  1.00 38.27  ? 55  LEU C CD2 1 
ATOM 1140 N N   . ALA B 2 61  ? 109.827 113.837 93.005  1.00 32.62  ? 56  ALA C N   1 
ATOM 1141 C CA  . ALA B 2 61  ? 109.745 115.273 92.794  1.00 33.69  ? 56  ALA C CA  1 
ATOM 1142 C C   . ALA B 2 61  ? 108.303 115.628 92.462  1.00 40.03  ? 56  ALA C C   1 
ATOM 1143 O O   . ALA B 2 61  ? 107.404 114.786 92.533  1.00 40.21  ? 56  ALA C O   1 
ATOM 1144 C CB  . ALA B 2 61  ? 110.708 115.726 91.692  1.00 33.74  ? 56  ALA C CB  1 
ATOM 1145 N N   . LYS B 2 62  ? 108.078 116.889 92.103  1.00 39.95  ? 57  LYS C N   1 
ATOM 1146 C CA  . LYS B 2 62  ? 106.731 117.337 91.779  1.00 35.43  ? 57  LYS C CA  1 
ATOM 1147 C C   . LYS B 2 62  ? 106.194 116.589 90.567  1.00 32.64  ? 57  LYS C C   1 
ATOM 1148 O O   . LYS B 2 62  ? 106.936 116.263 89.637  1.00 35.87  ? 57  LYS C O   1 
ATOM 1149 C CB  . LYS B 2 62  ? 106.718 118.843 91.508  1.00 34.43  ? 57  LYS C CB  1 
ATOM 1150 C CG  . LYS B 2 62  ? 106.913 119.698 92.740  1.00 32.26  ? 57  LYS C CG  1 
ATOM 1151 C CD  . LYS B 2 62  ? 106.702 121.170 92.440  1.00 32.95  ? 57  LYS C CD  1 
ATOM 1152 C CE  . LYS B 2 62  ? 107.840 121.752 91.630  1.00 33.21  ? 57  LYS C CE  1 
ATOM 1153 N NZ  . LYS B 2 62  ? 107.709 123.227 91.481  1.00 33.02  ? 57  LYS C NZ  1 
ATOM 1154 N N   . ILE B 2 63  ? 104.895 116.311 90.587  1.00 29.71  ? 58  ILE C N   1 
ATOM 1155 C CA  . ILE B 2 63  ? 104.191 115.717 89.457  1.00 32.49  ? 58  ILE C CA  1 
ATOM 1156 C C   . ILE B 2 63  ? 103.459 116.828 88.722  1.00 28.38  ? 58  ILE C C   1 
ATOM 1157 O O   . ILE B 2 63  ? 102.697 117.588 89.332  1.00 33.28  ? 58  ILE C O   1 
ATOM 1158 C CB  . ILE B 2 63  ? 103.218 114.621 89.921  1.00 32.11  ? 58  ILE C CB  1 
ATOM 1159 C CG1 . ILE B 2 63  ? 103.996 113.487 90.586  1.00 21.28  ? 58  ILE C CG1 1 
ATOM 1160 C CG2 . ILE B 2 63  ? 102.392 114.100 88.748  1.00 26.87  ? 58  ILE C CG2 1 
ATOM 1161 C CD1 . ILE B 2 63  ? 103.135 112.391 91.133  1.00 24.37  ? 58  ILE C CD1 1 
ATOM 1162 N N   . TYR B 2 64  ? 103.689 116.926 87.413  1.00 14.96  ? 59  TYR C N   1 
ATOM 1163 C CA  . TYR B 2 64  ? 103.124 117.999 86.607  1.00 24.95  ? 59  TYR C CA  1 
ATOM 1164 C C   . TYR B 2 64  ? 101.994 117.563 85.690  1.00 27.43  ? 59  TYR C C   1 
ATOM 1165 O O   . TYR B 2 64  ? 101.158 118.395 85.335  1.00 21.95  ? 59  TYR C O   1 
ATOM 1166 C CB  . TYR B 2 64  ? 104.220 118.658 85.765  1.00 27.33  ? 59  TYR C CB  1 
ATOM 1167 C CG  . TYR B 2 64  ? 104.820 119.869 86.434  1.00 33.56  ? 59  TYR C CG  1 
ATOM 1168 C CD1 . TYR B 2 64  ? 105.649 119.735 87.536  1.00 31.97  ? 59  TYR C CD1 1 
ATOM 1169 C CD2 . TYR B 2 64  ? 104.548 121.147 85.971  1.00 32.33  ? 59  TYR C CD2 1 
ATOM 1170 C CE1 . TYR B 2 64  ? 106.194 120.838 88.156  1.00 31.33  ? 59  TYR C CE1 1 
ATOM 1171 C CE2 . TYR B 2 64  ? 105.090 122.255 86.583  1.00 33.65  ? 59  TYR C CE2 1 
ATOM 1172 C CZ  . TYR B 2 64  ? 105.911 122.095 87.675  1.00 33.34  ? 59  TYR C CZ  1 
ATOM 1173 O OH  . TYR B 2 64  ? 106.456 123.195 88.290  1.00 38.57  ? 59  TYR C OH  1 
ATOM 1174 N N   . ALA B 2 65  ? 101.935 116.292 85.302  1.00 31.71  ? 60  ALA C N   1 
ATOM 1175 C CA  . ALA B 2 65  ? 100.890 115.838 84.400  1.00 22.15  ? 60  ALA C CA  1 
ATOM 1176 C C   . ALA B 2 65  ? 100.618 114.359 84.623  1.00 14.26  ? 60  ALA C C   1 
ATOM 1177 O O   . ALA B 2 65  ? 101.451 113.622 85.154  1.00 17.99  ? 60  ALA C O   1 
ATOM 1178 C CB  . ALA B 2 65  ? 101.268 116.092 82.936  1.00 17.83  ? 60  ALA C CB  1 
ATOM 1179 N N   . MET B 2 66  ? 99.427  113.939 84.207  1.00 15.43  ? 61  MET C N   1 
ATOM 1180 C CA  . MET B 2 66  ? 99.050  112.537 84.175  1.00 7.93   ? 61  MET C CA  1 
ATOM 1181 C C   . MET B 2 66  ? 97.975  112.365 83.113  1.00 20.19  ? 61  MET C C   1 
ATOM 1182 O O   . MET B 2 66  ? 97.386  113.338 82.635  1.00 15.52  ? 61  MET C O   1 
ATOM 1183 C CB  . MET B 2 66  ? 98.552  112.036 85.539  1.00 11.87  ? 61  MET C CB  1 
ATOM 1184 C CG  . MET B 2 66  ? 97.380  112.811 86.121  1.00 20.25  ? 61  MET C CG  1 
ATOM 1185 S SD  . MET B 2 66  ? 96.171  111.791 86.969  1.00 16.54  ? 61  MET C SD  1 
ATOM 1186 C CE  . MET B 2 66  ? 95.439  110.898 85.606  1.00 15.20  ? 61  MET C CE  1 
ATOM 1187 N N   . HIS B 2 67  ? 97.732  111.113 82.742  1.00 16.32  ? 62  HIS C N   1 
ATOM 1188 C CA  . HIS B 2 67  ? 96.789  110.797 81.682  1.00 7.79   ? 62  HIS C CA  1 
ATOM 1189 C C   . HIS B 2 67  ? 96.410  109.330 81.826  1.00 5.54   ? 62  HIS C C   1 
ATOM 1190 O O   . HIS B 2 67  ? 97.261  108.497 82.134  1.00 0.00   ? 62  HIS C O   1 
ATOM 1191 C CB  . HIS B 2 67  ? 97.404  111.089 80.303  1.00 7.09   ? 62  HIS C CB  1 
ATOM 1192 C CG  . HIS B 2 67  ? 96.403  111.200 79.195  1.00 4.08   ? 62  HIS C CG  1 
ATOM 1193 N ND1 . HIS B 2 67  ? 95.388  112.131 79.194  1.00 5.17   ? 62  HIS C ND1 1 
ATOM 1194 C CD2 . HIS B 2 67  ? 96.270  110.501 78.045  1.00 19.45  ? 62  HIS C CD2 1 
ATOM 1195 C CE1 . HIS B 2 67  ? 94.669  111.995 78.096  1.00 2.84   ? 62  HIS C CE1 1 
ATOM 1196 N NE2 . HIS B 2 67  ? 95.183  111.012 77.382  1.00 0.00   ? 62  HIS C NE2 1 
ATOM 1197 N N   . TRP B 2 68  ? 95.134  109.028 81.630  1.00 15.73  ? 63  TRP C N   1 
ATOM 1198 C CA  . TRP B 2 68  ? 94.637  107.670 81.768  1.00 18.49  ? 63  TRP C CA  1 
ATOM 1199 C C   . TRP B 2 68  ? 94.758  106.925 80.450  1.00 22.26  ? 63  TRP C C   1 
ATOM 1200 O O   . TRP B 2 68  ? 94.647  107.510 79.370  1.00 24.97  ? 63  TRP C O   1 
ATOM 1201 C CB  . TRP B 2 68  ? 93.169  107.656 82.203  1.00 15.93  ? 63  TRP C CB  1 
ATOM 1202 C CG  . TRP B 2 68  ? 92.921  107.977 83.638  1.00 16.17  ? 63  TRP C CG  1 
ATOM 1203 C CD1 . TRP B 2 68  ? 92.705  109.208 84.173  1.00 21.76  ? 63  TRP C CD1 1 
ATOM 1204 C CD2 . TRP B 2 68  ? 92.843  107.048 84.725  1.00 21.32  ? 63  TRP C CD2 1 
ATOM 1205 N NE1 . TRP B 2 68  ? 92.504  109.107 85.525  1.00 24.88  ? 63  TRP C NE1 1 
ATOM 1206 C CE2 . TRP B 2 68  ? 92.583  107.790 85.890  1.00 24.93  ? 63  TRP C CE2 1 
ATOM 1207 C CE3 . TRP B 2 68  ? 92.971  105.660 84.827  1.00 21.52  ? 63  TRP C CE3 1 
ATOM 1208 C CZ2 . TRP B 2 68  ? 92.449  107.193 87.142  1.00 20.69  ? 63  TRP C CZ2 1 
ATOM 1209 C CZ3 . TRP B 2 68  ? 92.839  105.072 86.069  1.00 16.85  ? 63  TRP C CZ3 1 
ATOM 1210 C CH2 . TRP B 2 68  ? 92.579  105.835 87.208  1.00 8.59   ? 63  TRP C CH2 1 
ATOM 1211 N N   . GLY B 2 69  ? 94.985  105.618 80.550  1.00 12.49  ? 64  GLY C N   1 
ATOM 1212 C CA  . GLY B 2 69  ? 94.822  104.760 79.397  1.00 3.67   ? 64  GLY C CA  1 
ATOM 1213 C C   . GLY B 2 69  ? 93.357  104.504 79.109  1.00 20.59  ? 64  GLY C C   1 
ATOM 1214 O O   . GLY B 2 69  ? 92.514  104.521 80.002  1.00 36.81  ? 64  GLY C O   1 
ATOM 1215 N N   . THR B 2 70  ? 93.047  104.257 77.836  1.00 26.69  ? 65  THR C N   1 
ATOM 1216 C CA  . THR B 2 70  ? 91.651  104.081 77.450  1.00 28.78  ? 65  THR C CA  1 
ATOM 1217 C C   . THR B 2 70  ? 91.005  102.918 78.192  1.00 35.17  ? 65  THR C C   1 
ATOM 1218 O O   . THR B 2 70  ? 89.778  102.881 78.336  1.00 41.40  ? 65  THR C O   1 
ATOM 1219 C CB  . THR B 2 70  ? 91.540  103.872 75.940  1.00 30.51  ? 65  THR C CB  1 
ATOM 1220 O OG1 . THR B 2 70  ? 92.347  102.755 75.545  1.00 25.54  ? 65  THR C OG1 1 
ATOM 1221 C CG2 . THR B 2 70  ? 91.996  105.117 75.201  1.00 35.18  ? 65  THR C CG2 1 
ATOM 1222 N N   . ASP B 2 71  ? 91.804  101.959 78.663  1.00 21.34  ? 66  ASP C N   1 
ATOM 1223 C CA  . ASP B 2 71  ? 91.281  100.897 79.512  1.00 21.32  ? 66  ASP C CA  1 
ATOM 1224 C C   . ASP B 2 71  ? 90.956  101.378 80.919  1.00 23.05  ? 66  ASP C C   1 
ATOM 1225 O O   . ASP B 2 71  ? 90.290  100.652 81.664  1.00 27.22  ? 66  ASP C O   1 
ATOM 1226 C CB  . ASP B 2 71  ? 92.279  99.741  79.582  1.00 24.01  ? 66  ASP C CB  1 
ATOM 1227 C CG  . ASP B 2 71  ? 93.600  100.144 80.202  1.00 27.24  ? 66  ASP C CG  1 
ATOM 1228 O OD1 . ASP B 2 71  ? 93.946  101.340 80.146  1.00 26.18  ? 66  ASP C OD1 1 
ATOM 1229 O OD2 . ASP B 2 71  ? 94.296  99.262  80.744  1.00 31.16  ? 66  ASP C OD2 1 
ATOM 1230 N N   . SER B 2 72  ? 91.404  102.576 81.297  1.00 24.52  ? 67  SER C N   1 
ATOM 1231 C CA  . SER B 2 72  ? 91.123  103.161 82.609  1.00 15.14  ? 67  SER C CA  1 
ATOM 1232 C C   . SER B 2 72  ? 91.702  102.320 83.742  1.00 15.14  ? 67  SER C C   1 
ATOM 1233 O O   . SER B 2 72  ? 91.203  102.346 84.867  1.00 32.06  ? 67  SER C O   1 
ATOM 1234 C CB  . SER B 2 72  ? 89.622  103.374 82.811  1.00 25.51  ? 67  SER C CB  1 
ATOM 1235 O OG  . SER B 2 72  ? 88.884  102.200 82.540  1.00 31.99  ? 67  SER C OG  1 
ATOM 1236 N N   . ARG B 2 73  ? 92.759  101.569 83.448  1.00 13.52  ? 68  ARG C N   1 
ATOM 1237 C CA  . ARG B 2 73  ? 93.515  100.828 84.449  1.00 27.59  ? 68  ARG C CA  1 
ATOM 1238 C C   . ARG B 2 73  ? 94.971  101.257 84.490  1.00 22.58  ? 68  ARG C C   1 
ATOM 1239 O O   . ARG B 2 73  ? 95.521  101.483 85.573  1.00 6.49   ? 68  ARG C O   1 
ATOM 1240 C CB  . ARG B 2 73  ? 93.420  99.318  84.173  1.00 25.76  ? 68  ARG C CB  1 
ATOM 1241 C CG  . ARG B 2 73  ? 94.393  98.488  84.980  1.00 7.42   ? 68  ARG C CG  1 
ATOM 1242 C CD  . ARG B 2 73  ? 93.981  97.040  85.041  1.00 12.84  ? 68  ARG C CD  1 
ATOM 1243 N NE  . ARG B 2 73  ? 94.818  96.289  85.967  1.00 14.24  ? 68  ARG C NE  1 
ATOM 1244 C CZ  . ARG B 2 73  ? 94.622  95.021  86.299  1.00 12.34  ? 68  ARG C CZ  1 
ATOM 1245 N NH1 . ARG B 2 73  ? 93.619  94.321  85.796  1.00 11.35  ? 68  ARG C NH1 1 
ATOM 1246 N NH2 . ARG B 2 73  ? 95.456  94.441  87.156  1.00 17.82  ? 68  ARG C NH2 1 
ATOM 1247 N N   . LEU B 2 74  ? 95.612  101.367 83.332  1.00 15.75  ? 69  LEU C N   1 
ATOM 1248 C CA  . LEU B 2 74  ? 96.971  101.868 83.238  1.00 14.76  ? 69  LEU C CA  1 
ATOM 1249 C C   . LEU B 2 74  ? 96.946  103.383 83.124  1.00 20.25  ? 69  LEU C C   1 
ATOM 1250 O O   . LEU B 2 74  ? 96.107  103.950 82.420  1.00 23.99  ? 69  LEU C O   1 
ATOM 1251 C CB  . LEU B 2 74  ? 97.686  101.262 82.029  1.00 20.79  ? 69  LEU C CB  1 
ATOM 1252 C CG  . LEU B 2 74  ? 98.001  99.767  82.086  1.00 13.45  ? 69  LEU C CG  1 
ATOM 1253 C CD1 . LEU B 2 74  ? 98.283  99.230  80.700  1.00 18.16  ? 69  LEU C CD1 1 
ATOM 1254 C CD2 . LEU B 2 74  ? 99.179  99.508  82.997  1.00 16.58  ? 69  LEU C CD2 1 
ATOM 1255 N N   . LEU B 2 75  ? 97.859  104.038 83.832  1.00 15.28  ? 70  LEU C N   1 
ATOM 1256 C CA  . LEU B 2 75  ? 97.980  105.483 83.769  1.00 9.87   ? 70  LEU C CA  1 
ATOM 1257 C C   . LEU B 2 75  ? 99.453  105.855 83.773  1.00 1.45   ? 70  LEU C C   1 
ATOM 1258 O O   . LEU B 2 75  ? 100.285 105.155 84.352  1.00 0.00   ? 70  LEU C O   1 
ATOM 1259 C CB  . LEU B 2 75  ? 97.231  106.165 84.931  1.00 11.66  ? 70  LEU C CB  1 
ATOM 1260 C CG  . LEU B 2 75  ? 97.637  105.836 86.369  1.00 12.77  ? 70  LEU C CG  1 
ATOM 1261 C CD1 . LEU B 2 75  ? 98.657  106.835 86.894  1.00 19.51  ? 70  LEU C CD1 1 
ATOM 1262 C CD2 . LEU B 2 75  ? 96.421  105.790 87.269  1.00 0.29   ? 70  LEU C CD2 1 
ATOM 1263 N N   . VAL B 2 76  ? 99.765  106.961 83.107  1.00 17.77  ? 71  VAL C N   1 
ATOM 1264 C CA  . VAL B 2 76  ? 101.133 107.433 82.953  1.00 18.08  ? 71  VAL C CA  1 
ATOM 1265 C C   . VAL B 2 76  ? 101.277 108.740 83.714  1.00 16.98  ? 71  VAL C C   1 
ATOM 1266 O O   . VAL B 2 76  ? 100.340 109.539 83.801  1.00 9.06   ? 71  VAL C O   1 
ATOM 1267 C CB  . VAL B 2 76  ? 101.514 107.602 81.464  1.00 17.05  ? 71  VAL C CB  1 
ATOM 1268 C CG1 . VAL B 2 76  ? 100.592 108.593 80.767  1.00 14.22  ? 71  VAL C CG1 1 
ATOM 1269 C CG2 . VAL B 2 76  ? 102.968 108.019 81.322  1.00 0.00   ? 71  VAL C CG2 1 
ATOM 1270 N N   . SER B 2 77  ? 102.461 108.947 84.285  1.00 10.06  ? 72  SER C N   1 
ATOM 1271 C CA  . SER B 2 77  ? 102.721 110.100 85.132  1.00 17.36  ? 72  SER C CA  1 
ATOM 1272 C C   . SER B 2 77  ? 104.079 110.684 84.792  1.00 13.97  ? 72  SER C C   1 
ATOM 1273 O O   . SER B 2 77  ? 105.076 109.960 84.764  1.00 6.50   ? 72  SER C O   1 
ATOM 1274 C CB  . SER B 2 77  ? 102.681 109.715 86.614  1.00 13.77  ? 72  SER C CB  1 
ATOM 1275 O OG  . SER B 2 77  ? 101.455 109.100 86.947  1.00 13.72  ? 72  SER C OG  1 
ATOM 1276 N N   . ALA B 2 78  ? 104.114 111.989 84.549  1.00 21.06  ? 73  ALA C N   1 
ATOM 1277 C CA  . ALA B 2 78  ? 105.354 112.725 84.368  1.00 20.99  ? 73  ALA C CA  1 
ATOM 1278 C C   . ALA B 2 78  ? 105.713 113.435 85.663  1.00 17.05  ? 73  ALA C C   1 
ATOM 1279 O O   . ALA B 2 78  ? 104.842 113.985 86.341  1.00 19.44  ? 73  ALA C O   1 
ATOM 1280 C CB  . ALA B 2 78  ? 105.235 113.744 83.234  1.00 18.76  ? 73  ALA C CB  1 
ATOM 1281 N N   . SER B 2 79  ? 106.996 113.411 86.005  1.00 16.70  ? 74  SER C N   1 
ATOM 1282 C CA  . SER B 2 79  ? 107.491 114.070 87.200  1.00 19.00  ? 74  SER C CA  1 
ATOM 1283 C C   . SER B 2 79  ? 108.772 114.814 86.860  1.00 29.75  ? 74  SER C C   1 
ATOM 1284 O O   . SER B 2 79  ? 109.473 114.479 85.904  1.00 37.44  ? 74  SER C O   1 
ATOM 1285 C CB  . SER B 2 79  ? 107.748 113.072 88.329  1.00 19.28  ? 74  SER C CB  1 
ATOM 1286 O OG  . SER B 2 79  ? 108.544 113.656 89.341  1.00 32.26  ? 74  SER C OG  1 
ATOM 1287 N N   . GLN B 2 80  ? 109.073 115.834 87.661  1.00 33.08  ? 75  GLN C N   1 
ATOM 1288 C CA  . GLN B 2 80  ? 110.283 116.625 87.481  1.00 40.36  ? 75  GLN C CA  1 
ATOM 1289 C C   . GLN B 2 80  ? 111.538 115.890 87.934  1.00 40.12  ? 75  GLN C C   1 
ATOM 1290 O O   . GLN B 2 80  ? 112.624 116.478 87.926  1.00 34.91  ? 75  GLN C O   1 
ATOM 1291 C CB  . GLN B 2 80  ? 110.156 117.957 88.223  1.00 37.77  ? 75  GLN C CB  1 
ATOM 1292 C CG  . GLN B 2 80  ? 109.152 118.907 87.589  1.00 38.48  ? 75  GLN C CG  1 
ATOM 1293 C CD  . GLN B 2 80  ? 109.430 120.362 87.910  1.00 42.75  ? 75  GLN C CD  1 
ATOM 1294 O OE1 . GLN B 2 80  ? 109.689 120.721 89.057  1.00 39.47  ? 75  GLN C OE1 1 
ATOM 1295 N NE2 . GLN B 2 80  ? 109.385 121.210 86.888  1.00 37.32  ? 75  GLN C NE2 1 
ATOM 1296 N N   . ASP B 2 81  ? 111.413 114.625 88.332  1.00 40.99  ? 76  ASP C N   1 
ATOM 1297 C CA  . ASP B 2 81  ? 112.570 113.774 88.556  1.00 38.48  ? 76  ASP C CA  1 
ATOM 1298 C C   . ASP B 2 81  ? 113.162 113.254 87.253  1.00 42.44  ? 76  ASP C C   1 
ATOM 1299 O O   . ASP B 2 81  ? 114.205 112.592 87.285  1.00 45.07  ? 76  ASP C O   1 
ATOM 1300 C CB  . ASP B 2 81  ? 112.184 112.596 89.455  1.00 31.29  ? 76  ASP C CB  1 
ATOM 1301 C CG  . ASP B 2 81  ? 113.391 111.855 90.004  1.00 45.32  ? 76  ASP C CG  1 
ATOM 1302 O OD1 . ASP B 2 81  ? 114.529 112.339 89.825  1.00 43.14  ? 76  ASP C OD1 1 
ATOM 1303 O OD2 . ASP B 2 81  ? 113.201 110.783 90.617  1.00 50.55  ? 76  ASP C OD2 1 
ATOM 1304 N N   . GLY B 2 82  ? 112.529 113.541 86.118  1.00 32.28  ? 77  GLY C N   1 
ATOM 1305 C CA  . GLY B 2 82  ? 112.955 113.012 84.842  1.00 32.15  ? 77  GLY C CA  1 
ATOM 1306 C C   . GLY B 2 82  ? 112.419 111.638 84.520  1.00 34.73  ? 77  GLY C C   1 
ATOM 1307 O O   . GLY B 2 82  ? 112.829 111.054 83.511  1.00 33.83  ? 77  GLY C O   1 
ATOM 1308 N N   . LYS B 2 83  ? 111.514 111.109 85.335  1.00 32.79  ? 78  LYS C N   1 
ATOM 1309 C CA  . LYS B 2 83  ? 110.992 109.763 85.180  1.00 30.33  ? 78  LYS C CA  1 
ATOM 1310 C C   . LYS B 2 83  ? 109.566 109.809 84.648  1.00 34.59  ? 78  LYS C C   1 
ATOM 1311 O O   . LYS B 2 83  ? 108.850 110.802 84.801  1.00 24.49  ? 78  LYS C O   1 
ATOM 1312 C CB  . LYS B 2 83  ? 111.023 109.017 86.518  1.00 25.10  ? 78  LYS C CB  1 
ATOM 1313 C CG  . LYS B 2 83  ? 111.279 107.519 86.413  1.00 29.04  ? 78  LYS C CG  1 
ATOM 1314 C CD  . LYS B 2 83  ? 112.667 107.186 85.865  1.00 40.20  ? 78  LYS C CD  1 
ATOM 1315 C CE  . LYS B 2 83  ? 113.791 107.702 86.753  1.00 38.50  ? 78  LYS C CE  1 
ATOM 1316 N NZ  . LYS B 2 83  ? 115.121 107.451 86.144  1.00 35.58  ? 78  LYS C NZ  1 
ATOM 1317 N N   . LEU B 2 84  ? 109.161 108.710 84.014  1.00 30.55  ? 79  LEU C N   1 
ATOM 1318 C CA  . LEU B 2 84  ? 107.804 108.557 83.492  1.00 19.05  ? 79  LEU C CA  1 
ATOM 1319 C C   . LEU B 2 84  ? 107.371 107.123 83.774  1.00 22.60  ? 79  LEU C C   1 
ATOM 1320 O O   . LEU B 2 84  ? 107.818 106.193 83.100  1.00 23.42  ? 79  LEU C O   1 
ATOM 1321 C CB  . LEU B 2 84  ? 107.751 108.886 82.007  1.00 22.27  ? 79  LEU C CB  1 
ATOM 1322 C CG  . LEU B 2 84  ? 106.369 108.879 81.359  1.00 15.62  ? 79  LEU C CG  1 
ATOM 1323 C CD1 . LEU B 2 84  ? 106.245 110.032 80.383  1.00 20.91  ? 79  LEU C CD1 1 
ATOM 1324 C CD2 . LEU B 2 84  ? 106.123 107.562 80.659  1.00 26.27  ? 79  LEU C CD2 1 
ATOM 1325 N N   . ILE B 2 85  ? 106.499 106.948 84.765  1.00 20.22  ? 80  ILE C N   1 
ATOM 1326 C CA  . ILE B 2 85  ? 106.140 105.630 85.276  1.00 13.85  ? 80  ILE C CA  1 
ATOM 1327 C C   . ILE B 2 85  ? 104.772 105.238 84.739  1.00 6.55   ? 80  ILE C C   1 
ATOM 1328 O O   . ILE B 2 85  ? 103.821 106.025 84.796  1.00 3.71   ? 80  ILE C O   1 
ATOM 1329 C CB  . ILE B 2 85  ? 106.157 105.607 86.816  1.00 4.99   ? 80  ILE C CB  1 
ATOM 1330 C CG1 . ILE B 2 85  ? 107.549 105.973 87.329  1.00 12.45  ? 80  ILE C CG1 1 
ATOM 1331 C CG2 . ILE B 2 85  ? 105.764 104.229 87.345  1.00 17.20  ? 80  ILE C CG2 1 
ATOM 1332 C CD1 . ILE B 2 85  ? 107.672 106.000 88.829  1.00 18.52  ? 80  ILE C CD1 1 
ATOM 1333 N N   . ILE B 2 86  ? 104.680 104.025 84.203  1.00 16.37  ? 81  ILE C N   1 
ATOM 1334 C CA  . ILE B 2 86  ? 103.402 103.398 83.897  1.00 7.90   ? 81  ILE C CA  1 
ATOM 1335 C C   . ILE B 2 86  ? 102.943 102.649 85.139  1.00 24.45  ? 81  ILE C C   1 
ATOM 1336 O O   . ILE B 2 86  ? 103.707 101.874 85.724  1.00 16.24  ? 81  ILE C O   1 
ATOM 1337 C CB  . ILE B 2 86  ? 103.521 102.452 82.690  1.00 12.84  ? 81  ILE C CB  1 
ATOM 1338 C CG1 . ILE B 2 86  ? 104.019 103.198 81.444  1.00 28.89  ? 81  ILE C CG1 1 
ATOM 1339 C CG2 . ILE B 2 86  ? 102.193 101.776 82.409  1.00 12.07  ? 81  ILE C CG2 1 
ATOM 1340 C CD1 . ILE B 2 86  ? 103.018 104.139 80.826  1.00 6.35   ? 81  ILE C CD1 1 
ATOM 1341 N N   . TRP B 2 87  ? 101.705 102.892 85.554  1.00 23.88  ? 82  TRP C N   1 
ATOM 1342 C CA  . TRP B 2 87  ? 101.166 102.354 86.793  1.00 2.40   ? 82  TRP C CA  1 
ATOM 1343 C C   . TRP B 2 87  ? 100.063 101.355 86.494  1.00 9.00   ? 82  TRP C C   1 
ATOM 1344 O O   . TRP B 2 87  ? 99.219  101.593 85.627  1.00 12.29  ? 82  TRP C O   1 
ATOM 1345 C CB  . TRP B 2 87  ? 100.586 103.457 87.682  1.00 14.64  ? 82  TRP C CB  1 
ATOM 1346 C CG  . TRP B 2 87  ? 101.549 104.487 88.144  1.00 17.81  ? 82  TRP C CG  1 
ATOM 1347 C CD1 . TRP B 2 87  ? 101.805 105.688 87.558  1.00 4.18   ? 82  TRP C CD1 1 
ATOM 1348 C CD2 . TRP B 2 87  ? 102.374 104.423 89.311  1.00 20.53  ? 82  TRP C CD2 1 
ATOM 1349 N NE1 . TRP B 2 87  ? 102.746 106.374 88.282  1.00 10.51  ? 82  TRP C NE1 1 
ATOM 1350 C CE2 . TRP B 2 87  ? 103.111 105.619 89.365  1.00 24.47  ? 82  TRP C CE2 1 
ATOM 1351 C CE3 . TRP B 2 87  ? 102.562 103.469 90.316  1.00 7.26   ? 82  TRP C CE3 1 
ATOM 1352 C CZ2 . TRP B 2 87  ? 104.024 105.887 90.382  1.00 15.44  ? 82  TRP C CZ2 1 
ATOM 1353 C CZ3 . TRP B 2 87  ? 103.465 103.736 91.319  1.00 9.96   ? 82  TRP C CZ3 1 
ATOM 1354 C CH2 . TRP B 2 87  ? 104.186 104.934 91.347  1.00 17.81  ? 82  TRP C CH2 1 
ATOM 1355 N N   . ASP B 2 88  ? 100.067 100.243 87.219  1.00 12.72  ? 83  ASP C N   1 
ATOM 1356 C CA  . ASP B 2 88  ? 98.897  99.380  87.301  1.00 13.65  ? 83  ASP C CA  1 
ATOM 1357 C C   . ASP B 2 88  ? 98.045  99.910  88.446  1.00 24.63  ? 83  ASP C C   1 
ATOM 1358 O O   . ASP B 2 88  ? 98.419  99.793  89.616  1.00 31.37  ? 83  ASP C O   1 
ATOM 1359 C CB  . ASP B 2 88  ? 99.284  97.922  87.520  1.00 15.21  ? 83  ASP C CB  1 
ATOM 1360 C CG  . ASP B 2 88  ? 98.116  96.979  87.327  1.00 22.11  ? 83  ASP C CG  1 
ATOM 1361 O OD1 . ASP B 2 88  ? 97.034  97.449  86.929  1.00 25.25  ? 83  ASP C OD1 1 
ATOM 1362 O OD2 . ASP B 2 88  ? 98.276  95.767  87.570  1.00 14.30  ? 83  ASP C OD2 1 
ATOM 1363 N N   . SER B 2 89  ? 96.910  100.516 88.105  1.00 32.87  ? 84  SER C N   1 
ATOM 1364 C CA  . SER B 2 89  ? 96.124  101.227 89.104  1.00 19.91  ? 84  SER C CA  1 
ATOM 1365 C C   . SER B 2 89  ? 95.485  100.274 90.104  1.00 25.59  ? 84  SER C C   1 
ATOM 1366 O O   . SER B 2 89  ? 95.320  100.631 91.275  1.00 38.93  ? 84  SER C O   1 
ATOM 1367 C CB  . SER B 2 89  ? 95.056  102.067 88.411  1.00 21.84  ? 84  SER C CB  1 
ATOM 1368 O OG  . SER B 2 89  ? 94.249  102.737 89.352  1.00 31.82  ? 84  SER C OG  1 
ATOM 1369 N N   . TYR B 2 90  ? 95.121  99.067  89.669  1.00 15.38  ? 85  TYR C N   1 
ATOM 1370 C CA  . TYR B 2 90  ? 94.414  98.150  90.555  1.00 7.93   ? 85  TYR C CA  1 
ATOM 1371 C C   . TYR B 2 90  ? 95.323  97.621  91.656  1.00 12.89  ? 85  TYR C C   1 
ATOM 1372 O O   . TYR B 2 90  ? 94.904  97.519  92.814  1.00 26.82  ? 85  TYR C O   1 
ATOM 1373 C CB  . TYR B 2 90  ? 93.826  96.991  89.754  1.00 18.49  ? 85  TYR C CB  1 
ATOM 1374 C CG  . TYR B 2 90  ? 92.645  97.354  88.881  1.00 21.31  ? 85  TYR C CG  1 
ATOM 1375 C CD1 . TYR B 2 90  ? 92.349  98.673  88.576  1.00 6.64   ? 85  TYR C CD1 1 
ATOM 1376 C CD2 . TYR B 2 90  ? 91.819  96.367  88.365  1.00 25.62  ? 85  TYR C CD2 1 
ATOM 1377 C CE1 . TYR B 2 90  ? 91.274  98.996  87.783  1.00 14.01  ? 85  TYR C CE1 1 
ATOM 1378 C CE2 . TYR B 2 90  ? 90.740  96.682  87.571  1.00 19.42  ? 85  TYR C CE2 1 
ATOM 1379 C CZ  . TYR B 2 90  ? 90.473  97.998  87.284  1.00 16.07  ? 85  TYR C CZ  1 
ATOM 1380 O OH  . TYR B 2 90  ? 89.398  98.314  86.490  1.00 25.72  ? 85  TYR C OH  1 
ATOM 1381 N N   . THR B 2 91  ? 96.568  97.283  91.323  1.00 24.32  ? 86  THR C N   1 
ATOM 1382 C CA  . THR B 2 91  ? 97.488  96.663  92.266  1.00 26.83  ? 86  THR C CA  1 
ATOM 1383 C C   . THR B 2 91  ? 98.612  97.588  92.704  1.00 17.55  ? 86  THR C C   1 
ATOM 1384 O O   . THR B 2 91  ? 99.407  97.203  93.567  1.00 25.91  ? 86  THR C O   1 
ATOM 1385 C CB  . THR B 2 91  ? 98.100  95.395  91.658  1.00 17.56  ? 86  THR C CB  1 
ATOM 1386 O OG1 . THR B 2 91  ? 98.981  95.754  90.591  1.00 16.99  ? 86  THR C OG1 1 
ATOM 1387 C CG2 . THR B 2 91  ? 97.022  94.471  91.126  1.00 22.18  ? 86  THR C CG2 1 
ATOM 1388 N N   . THR B 2 92  ? 98.699  98.794  92.151  1.00 14.82  ? 87  THR C N   1 
ATOM 1389 C CA  . THR B 2 92  ? 99.806  99.707  92.429  1.00 25.44  ? 87  THR C CA  1 
ATOM 1390 C C   . THR B 2 92  ? 101.137 99.135  91.947  1.00 31.87  ? 87  THR C C   1 
ATOM 1391 O O   . THR B 2 92  ? 102.201 99.502  92.450  1.00 37.25  ? 87  THR C O   1 
ATOM 1392 C CB  . THR B 2 92  ? 99.893  100.046 93.921  1.00 35.40  ? 87  THR C CB  1 
ATOM 1393 O OG1 . THR B 2 92  ? 100.262 98.877  94.662  1.00 36.31  ? 87  THR C OG1 1 
ATOM 1394 C CG2 . THR B 2 92  ? 98.560  100.573 94.434  1.00 33.00  ? 87  THR C CG2 1 
ATOM 1395 N N   . ASN B 2 93  ? 101.088 98.237  90.966  1.00 35.15  ? 88  ASN C N   1 
ATOM 1396 C CA  . ASN B 2 93  ? 102.298 97.674  90.386  1.00 22.59  ? 88  ASN C CA  1 
ATOM 1397 C C   . ASN B 2 93  ? 102.884 98.636  89.365  1.00 20.13  ? 88  ASN C C   1 
ATOM 1398 O O   . ASN B 2 93  ? 102.154 99.295  88.621  1.00 14.07  ? 88  ASN C O   1 
ATOM 1399 C CB  . ASN B 2 93  ? 102.002 96.330  89.715  1.00 8.89   ? 88  ASN C CB  1 
ATOM 1400 C CG  . ASN B 2 93  ? 102.057 95.163  90.680  1.00 14.29  ? 88  ASN C CG  1 
ATOM 1401 O OD1 . ASN B 2 93  ? 102.630 95.261  91.762  1.00 28.44  ? 88  ASN C OD1 1 
ATOM 1402 N ND2 . ASN B 2 93  ? 101.473 94.043  90.281  1.00 22.08  ? 88  ASN C ND2 1 
ATOM 1403 N N   . LYS B 2 94  ? 104.210 98.711  89.330  1.00 29.39  ? 89  LYS C N   1 
ATOM 1404 C CA  . LYS B 2 94  ? 104.920 99.517  88.345  1.00 21.36  ? 89  LYS C CA  1 
ATOM 1405 C C   . LYS B 2 94  ? 105.165 98.660  87.109  1.00 13.72  ? 89  LYS C C   1 
ATOM 1406 O O   . LYS B 2 94  ? 105.913 97.680  87.163  1.00 15.70  ? 89  LYS C O   1 
ATOM 1407 C CB  . LYS B 2 94  ? 106.231 100.040 88.920  1.00 23.11  ? 89  LYS C CB  1 
ATOM 1408 C CG  . LYS B 2 94  ? 106.053 100.959 90.102  1.00 25.50  ? 89  LYS C CG  1 
ATOM 1409 C CD  . LYS B 2 94  ? 107.363 101.593 90.512  1.00 19.48  ? 89  LYS C CD  1 
ATOM 1410 C CE  . LYS B 2 94  ? 107.162 102.587 91.632  1.00 22.34  ? 89  LYS C CE  1 
ATOM 1411 N NZ  . LYS B 2 94  ? 106.571 101.947 92.836  1.00 29.63  ? 89  LYS C NZ  1 
ATOM 1412 N N   . VAL B 2 95  ? 104.538 99.035  85.994  1.00 17.24  ? 90  VAL C N   1 
ATOM 1413 C CA  . VAL B 2 95  ? 104.658 98.254  84.769  1.00 4.58   ? 90  VAL C CA  1 
ATOM 1414 C C   . VAL B 2 95  ? 105.909 98.647  83.996  1.00 5.28   ? 90  VAL C C   1 
ATOM 1415 O O   . VAL B 2 95  ? 106.629 97.786  83.482  1.00 13.79  ? 90  VAL C O   1 
ATOM 1416 C CB  . VAL B 2 95  ? 103.390 98.422  83.916  1.00 0.00   ? 90  VAL C CB  1 
ATOM 1417 C CG1 . VAL B 2 95  ? 103.401 97.455  82.752  1.00 24.05  ? 90  VAL C CG1 1 
ATOM 1418 C CG2 . VAL B 2 95  ? 102.147 98.226  84.762  1.00 3.69   ? 90  VAL C CG2 1 
ATOM 1419 N N   . HIS B 2 96  ? 106.184 99.946  83.899  1.00 21.96  ? 91  HIS C N   1 
ATOM 1420 C CA  . HIS B 2 96  ? 107.344 100.464 83.190  1.00 20.56  ? 91  HIS C CA  1 
ATOM 1421 C C   . HIS B 2 96  ? 107.889 101.665 83.948  1.00 18.45  ? 91  HIS C C   1 
ATOM 1422 O O   . HIS B 2 96  ? 107.188 102.291 84.745  1.00 13.93  ? 91  HIS C O   1 
ATOM 1423 C CB  . HIS B 2 96  ? 107.006 100.878 81.747  1.00 20.26  ? 91  HIS C CB  1 
ATOM 1424 C CG  . HIS B 2 96  ? 106.737 99.729  80.825  1.00 19.77  ? 91  HIS C CG  1 
ATOM 1425 N ND1 . HIS B 2 96  ? 105.473 99.416  80.375  1.00 16.19  ? 91  HIS C ND1 1 
ATOM 1426 C CD2 . HIS B 2 96  ? 107.571 98.824  80.260  1.00 20.39  ? 91  HIS C CD2 1 
ATOM 1427 C CE1 . HIS B 2 96  ? 105.539 98.365  79.578  1.00 13.05  ? 91  HIS C CE1 1 
ATOM 1428 N NE2 . HIS B 2 96  ? 106.801 97.987  79.492  1.00 18.70  ? 91  HIS C NE2 1 
ATOM 1429 N N   . ALA B 2 97  ? 109.158 101.982 83.692  1.00 32.12  ? 92  ALA C N   1 
ATOM 1430 C CA  . ALA B 2 97  ? 109.806 103.174 84.247  1.00 24.90  ? 92  ALA C CA  1 
ATOM 1431 C C   . ALA B 2 97  ? 110.730 103.731 83.165  1.00 32.44  ? 92  ALA C C   1 
ATOM 1432 O O   . ALA B 2 97  ? 111.881 103.307 83.039  1.00 31.60  ? 92  ALA C O   1 
ATOM 1433 C CB  . ALA B 2 97  ? 110.561 102.851 85.529  1.00 27.63  ? 92  ALA C CB  1 
ATOM 1434 N N   . ILE B 2 98  ? 110.219 104.686 82.395  1.00 27.87  ? 93  ILE C N   1 
ATOM 1435 C CA  . ILE B 2 98  ? 110.926 105.233 81.239  1.00 20.98  ? 93  ILE C CA  1 
ATOM 1436 C C   . ILE B 2 98  ? 111.743 106.444 81.679  1.00 26.30  ? 93  ILE C C   1 
ATOM 1437 O O   . ILE B 2 98  ? 111.180 107.381 82.262  1.00 27.66  ? 93  ILE C O   1 
ATOM 1438 C CB  . ILE B 2 98  ? 109.944 105.613 80.117  1.00 24.86  ? 93  ILE C CB  1 
ATOM 1439 C CG1 . ILE B 2 98  ? 109.083 104.413 79.715  1.00 26.64  ? 93  ILE C CG1 1 
ATOM 1440 C CG2 . ILE B 2 98  ? 110.692 106.145 78.905  1.00 27.01  ? 93  ILE C CG2 1 
ATOM 1441 C CD1 . ILE B 2 98  ? 107.764 104.316 80.446  1.00 26.31  ? 93  ILE C CD1 1 
ATOM 1442 N N   . PRO B 2 99  ? 113.052 106.478 81.441  1.00 31.28  ? 94  PRO C N   1 
ATOM 1443 C CA  . PRO B 2 99  ? 113.818 107.691 81.734  1.00 35.29  ? 94  PRO C CA  1 
ATOM 1444 C C   . PRO B 2 99  ? 113.743 108.701 80.599  1.00 34.66  ? 94  PRO C C   1 
ATOM 1445 O O   . PRO B 2 99  ? 113.658 108.347 79.421  1.00 34.10  ? 94  PRO C O   1 
ATOM 1446 C CB  . PRO B 2 99  ? 115.246 107.165 81.915  1.00 38.18  ? 94  PRO C CB  1 
ATOM 1447 C CG  . PRO B 2 99  ? 115.307 105.973 81.047  1.00 34.64  ? 94  PRO C CG  1 
ATOM 1448 C CD  . PRO B 2 99  ? 113.931 105.364 81.042  1.00 32.28  ? 94  PRO C CD  1 
ATOM 1449 N N   . LEU B 2 100 ? 113.778 109.977 80.973  1.00 36.08  ? 95  LEU C N   1 
ATOM 1450 C CA  . LEU B 2 100 ? 113.656 111.081 80.033  1.00 35.95  ? 95  LEU C CA  1 
ATOM 1451 C C   . LEU B 2 100 ? 114.970 111.843 79.936  1.00 35.92  ? 95  LEU C C   1 
ATOM 1452 O O   . LEU B 2 100 ? 115.743 111.905 80.895  1.00 38.79  ? 95  LEU C O   1 
ATOM 1453 C CB  . LEU B 2 100 ? 112.542 112.044 80.455  1.00 30.23  ? 95  LEU C CB  1 
ATOM 1454 C CG  . LEU B 2 100 ? 111.167 111.449 80.751  1.00 28.12  ? 95  LEU C CG  1 
ATOM 1455 C CD1 . LEU B 2 100 ? 110.198 112.556 81.103  1.00 31.89  ? 95  LEU C CD1 1 
ATOM 1456 C CD2 . LEU B 2 100 ? 110.647 110.628 79.585  1.00 28.12  ? 95  LEU C CD2 1 
ATOM 1457 N N   . ARG B 2 101 ? 115.216 112.431 78.762  1.00 38.51  ? 96  ARG C N   1 
ATOM 1458 C CA  . ARG B 2 101 ? 116.423 113.233 78.583  1.00 42.30  ? 96  ARG C CA  1 
ATOM 1459 C C   . ARG B 2 101 ? 116.308 114.575 79.295  1.00 45.46  ? 96  ARG C C   1 
ATOM 1460 O O   . ARG B 2 101 ? 117.281 115.052 79.891  1.00 44.31  ? 96  ARG C O   1 
ATOM 1461 C CB  . ARG B 2 101 ? 116.704 113.451 77.098  1.00 43.28  ? 96  ARG C CB  1 
ATOM 1462 C CG  . ARG B 2 101 ? 116.949 112.180 76.310  1.00 44.10  ? 96  ARG C CG  1 
ATOM 1463 C CD  . ARG B 2 101 ? 117.867 112.434 75.126  1.00 43.59  ? 96  ARG C CD  1 
ATOM 1464 N NE  . ARG B 2 101 ? 117.559 113.683 74.439  1.00 45.97  ? 96  ARG C NE  1 
ATOM 1465 C CZ  . ARG B 2 101 ? 118.272 114.183 73.439  1.00 50.25  ? 96  ARG C CZ  1 
ATOM 1466 N NH1 . ARG B 2 101 ? 119.336 113.555 72.965  1.00 48.99  ? 96  ARG C NH1 1 
ATOM 1467 N NH2 . ARG B 2 101 ? 117.909 115.343 72.900  1.00 45.84  ? 96  ARG C NH2 1 
ATOM 1468 N N   . SER B 2 102 ? 115.137 115.201 79.240  1.00 50.02  ? 97  SER C N   1 
ATOM 1469 C CA  . SER B 2 102 ? 114.904 116.493 79.869  1.00 45.12  ? 97  SER C CA  1 
ATOM 1470 C C   . SER B 2 102 ? 113.939 116.318 81.031  1.00 43.76  ? 97  SER C C   1 
ATOM 1471 O O   . SER B 2 102 ? 112.848 115.762 80.862  1.00 42.97  ? 97  SER C O   1 
ATOM 1472 C CB  . SER B 2 102 ? 114.346 117.500 78.861  1.00 49.63  ? 97  SER C CB  1 
ATOM 1473 O OG  . SER B 2 102 ? 114.302 118.804 79.414  1.00 47.66  ? 97  SER C OG  1 
ATOM 1474 N N   . SER B 2 103 ? 114.345 116.794 82.205  1.00 51.04  ? 98  SER C N   1 
ATOM 1475 C CA  . SER B 2 103 ? 113.531 116.705 83.409  1.00 48.53  ? 98  SER C CA  1 
ATOM 1476 C C   . SER B 2 103 ? 112.528 117.843 83.535  1.00 46.82  ? 98  SER C C   1 
ATOM 1477 O O   . SER B 2 103 ? 111.716 117.828 84.465  1.00 47.46  ? 98  SER C O   1 
ATOM 1478 C CB  . SER B 2 103 ? 114.436 116.677 84.642  1.00 45.77  ? 98  SER C CB  1 
ATOM 1479 O OG  . SER B 2 103 ? 115.355 117.754 84.620  1.00 50.14  ? 98  SER C OG  1 
ATOM 1480 N N   . TRP B 2 104 ? 112.558 118.822 82.635  1.00 41.50  ? 99  TRP C N   1 
ATOM 1481 C CA  . TRP B 2 104 ? 111.598 119.923 82.635  1.00 48.46  ? 99  TRP C CA  1 
ATOM 1482 C C   . TRP B 2 104 ? 110.464 119.540 81.690  1.00 43.86  ? 99  TRP C C   1 
ATOM 1483 O O   . TRP B 2 104 ? 110.488 119.859 80.502  1.00 43.94  ? 99  TRP C O   1 
ATOM 1484 C CB  . TRP B 2 104 ? 112.263 121.227 82.216  1.00 48.39  ? 99  TRP C CB  1 
ATOM 1485 C CG  . TRP B 2 104 ? 113.463 121.588 83.026  1.00 48.03  ? 99  TRP C CG  1 
ATOM 1486 C CD1 . TRP B 2 104 ? 114.766 121.530 82.630  1.00 47.03  ? 99  TRP C CD1 1 
ATOM 1487 C CD2 . TRP B 2 104 ? 113.475 122.068 84.375  1.00 46.99  ? 99  TRP C CD2 1 
ATOM 1488 N NE1 . TRP B 2 104 ? 115.588 121.943 83.649  1.00 49.66  ? 99  TRP C NE1 1 
ATOM 1489 C CE2 . TRP B 2 104 ? 114.819 122.277 84.731  1.00 51.31  ? 99  TRP C CE2 1 
ATOM 1490 C CE3 . TRP B 2 104 ? 112.479 122.337 85.317  1.00 45.94  ? 99  TRP C CE3 1 
ATOM 1491 C CZ2 . TRP B 2 104 ? 115.192 122.745 85.987  1.00 51.61  ? 99  TRP C CZ2 1 
ATOM 1492 C CZ3 . TRP B 2 104 ? 112.852 122.800 86.561  1.00 49.10  ? 99  TRP C CZ3 1 
ATOM 1493 C CH2 . TRP B 2 104 ? 114.195 122.999 86.886  1.00 48.75  ? 99  TRP C CH2 1 
ATOM 1494 N N   . VAL B 2 105 ? 109.459 118.857 82.231  1.00 27.51  ? 100 VAL C N   1 
ATOM 1495 C CA  . VAL B 2 105 ? 108.355 118.312 81.452  1.00 27.39  ? 100 VAL C CA  1 
ATOM 1496 C C   . VAL B 2 105 ? 107.051 118.853 82.016  1.00 25.07  ? 100 VAL C C   1 
ATOM 1497 O O   . VAL B 2 105 ? 106.895 118.974 83.235  1.00 26.73  ? 100 VAL C O   1 
ATOM 1498 C CB  . VAL B 2 105 ? 108.364 116.768 81.467  1.00 31.88  ? 100 VAL C CB  1 
ATOM 1499 C CG1 . VAL B 2 105 ? 107.194 116.205 80.675  1.00 27.61  ? 100 VAL C CG1 1 
ATOM 1500 C CG2 . VAL B 2 105 ? 109.672 116.247 80.905  1.00 28.25  ? 100 VAL C CG2 1 
ATOM 1501 N N   . MET B 2 106 ? 106.118 119.184 81.124  1.00 30.16  ? 101 MET C N   1 
ATOM 1502 C CA  . MET B 2 106 ? 104.835 119.754 81.504  1.00 22.43  ? 101 MET C CA  1 
ATOM 1503 C C   . MET B 2 106 ? 103.636 118.934 81.055  1.00 22.01  ? 101 MET C C   1 
ATOM 1504 O O   . MET B 2 106 ? 102.518 119.230 81.489  1.00 26.64  ? 101 MET C O   1 
ATOM 1505 C CB  . MET B 2 106 ? 104.691 121.172 80.928  1.00 24.70  ? 101 MET C CB  1 
ATOM 1506 C CG  . MET B 2 106 ? 105.792 122.130 81.347  1.00 28.84  ? 101 MET C CG  1 
ATOM 1507 S SD  . MET B 2 106 ? 105.705 123.721 80.509  1.00 30.58  ? 101 MET C SD  1 
ATOM 1508 C CE  . MET B 2 106 ? 104.263 124.429 81.286  1.00 28.29  ? 101 MET C CE  1 
ATOM 1509 N N   . THR B 2 107 ? 103.822 117.927 80.203  1.00 22.21  ? 102 THR C N   1 
ATOM 1510 C CA  . THR B 2 107 ? 102.705 117.237 79.580  1.00 23.80  ? 102 THR C CA  1 
ATOM 1511 C C   . THR B 2 107 ? 102.961 115.740 79.525  1.00 21.22  ? 102 THR C C   1 
ATOM 1512 O O   . THR B 2 107 ? 104.106 115.287 79.459  1.00 19.91  ? 102 THR C O   1 
ATOM 1513 C CB  . THR B 2 107 ? 102.453 117.742 78.156  1.00 28.63  ? 102 THR C CB  1 
ATOM 1514 O OG1 . THR B 2 107 ? 103.540 117.356 77.310  1.00 24.90  ? 102 THR C OG1 1 
ATOM 1515 C CG2 . THR B 2 107 ? 102.333 119.241 78.135  1.00 21.43  ? 102 THR C CG2 1 
ATOM 1516 N N   . CYS B 2 108 ? 101.870 114.984 79.552  1.00 17.64  ? 103 CYS C N   1 
ATOM 1517 C CA  . CYS B 2 108 ? 101.846 113.562 79.259  1.00 13.50  ? 103 CYS C CA  1 
ATOM 1518 C C   . CYS B 2 108 ? 100.862 113.317 78.125  1.00 14.43  ? 103 CYS C C   1 
ATOM 1519 O O   . CYS B 2 108 ? 100.114 114.206 77.714  1.00 30.62  ? 103 CYS C O   1 
ATOM 1520 C CB  . CYS B 2 108 ? 101.435 112.737 80.486  1.00 11.44  ? 103 CYS C CB  1 
ATOM 1521 S SG  . CYS B 2 108 ? 102.726 112.458 81.688  1.00 18.06  ? 103 CYS C SG  1 
ATOM 1522 N N   . ALA B 2 109 ? 100.875 112.092 77.614  1.00 17.48  ? 104 ALA C N   1 
ATOM 1523 C CA  . ALA B 2 109 ? 99.845  111.634 76.698  1.00 8.64   ? 104 ALA C CA  1 
ATOM 1524 C C   . ALA B 2 109 ? 99.978  110.129 76.553  1.00 22.92  ? 104 ALA C C   1 
ATOM 1525 O O   . ALA B 2 109 ? 101.080 109.579 76.627  1.00 28.20  ? 104 ALA C O   1 
ATOM 1526 C CB  . ALA B 2 109 ? 99.945  112.318 75.332  1.00 1.78   ? 104 ALA C CB  1 
ATOM 1527 N N   . TYR B 2 110 ? 98.841  109.475 76.355  1.00 20.10  ? 105 TYR C N   1 
ATOM 1528 C CA  . TYR B 2 110 ? 98.762  108.031 76.216  1.00 0.00   ? 105 TYR C CA  1 
ATOM 1529 C C   . TYR B 2 110 ? 97.970  107.747 74.954  1.00 20.73  ? 105 TYR C C   1 
ATOM 1530 O O   . TYR B 2 110 ? 96.810  108.156 74.847  1.00 22.32  ? 105 TYR C O   1 
ATOM 1531 C CB  . TYR B 2 110 ? 98.096  107.411 77.445  1.00 4.35   ? 105 TYR C CB  1 
ATOM 1532 C CG  . TYR B 2 110 ? 98.021  105.904 77.455  1.00 24.32  ? 105 TYR C CG  1 
ATOM 1533 C CD1 . TYR B 2 110 ? 97.066  105.233 76.704  1.00 12.55  ? 105 TYR C CD1 1 
ATOM 1534 C CD2 . TYR B 2 110 ? 98.882  105.152 78.242  1.00 22.14  ? 105 TYR C CD2 1 
ATOM 1535 C CE1 . TYR B 2 110 ? 96.979  103.862 76.724  1.00 14.42  ? 105 TYR C CE1 1 
ATOM 1536 C CE2 . TYR B 2 110 ? 98.808  103.775 78.264  1.00 10.51  ? 105 TYR C CE2 1 
ATOM 1537 C CZ  . TYR B 2 110 ? 97.855  103.135 77.503  1.00 21.36  ? 105 TYR C CZ  1 
ATOM 1538 O OH  . TYR B 2 110 ? 97.774  101.761 77.528  1.00 19.46  ? 105 TYR C OH  1 
ATOM 1539 N N   . ALA B 2 111 ? 98.591  107.066 73.999  1.00 13.67  ? 106 ALA C N   1 
ATOM 1540 C CA  . ALA B 2 111 ? 97.928  106.836 72.728  1.00 6.71   ? 106 ALA C CA  1 
ATOM 1541 C C   . ALA B 2 111 ? 96.676  105.990 72.947  1.00 18.81  ? 106 ALA C C   1 
ATOM 1542 O O   . ALA B 2 111 ? 96.702  105.041 73.738  1.00 25.03  ? 106 ALA C O   1 
ATOM 1543 C CB  . ALA B 2 111 ? 98.869  106.136 71.750  1.00 3.73   ? 106 ALA C CB  1 
ATOM 1544 N N   . PRO B 2 112 ? 95.566  106.295 72.268  1.00 21.25  ? 107 PRO C N   1 
ATOM 1545 C CA  . PRO B 2 112 ? 94.352  105.490 72.483  1.00 18.25  ? 107 PRO C CA  1 
ATOM 1546 C C   . PRO B 2 112 ? 94.561  104.007 72.228  1.00 27.86  ? 107 PRO C C   1 
ATOM 1547 O O   . PRO B 2 112 ? 93.910  103.177 72.873  1.00 25.62  ? 107 PRO C O   1 
ATOM 1548 C CB  . PRO B 2 112 ? 93.350  106.099 71.494  1.00 22.19  ? 107 PRO C CB  1 
ATOM 1549 C CG  . PRO B 2 112 ? 93.836  107.473 71.253  1.00 25.32  ? 107 PRO C CG  1 
ATOM 1550 C CD  . PRO B 2 112 ? 95.323  107.409 71.335  1.00 20.34  ? 107 PRO C CD  1 
ATOM 1551 N N   . SER B 2 113 ? 95.451  103.648 71.300  1.00 31.06  ? 108 SER C N   1 
ATOM 1552 C CA  . SER B 2 113 ? 95.762  102.242 71.072  1.00 25.24  ? 108 SER C CA  1 
ATOM 1553 C C   . SER B 2 113 ? 96.495  101.630 72.257  1.00 25.42  ? 108 SER C C   1 
ATOM 1554 O O   . SER B 2 113 ? 96.279  100.456 72.580  1.00 37.90  ? 108 SER C O   1 
ATOM 1555 C CB  . SER B 2 113 ? 96.601  102.096 69.807  1.00 26.30  ? 108 SER C CB  1 
ATOM 1556 O OG  . SER B 2 113 ? 97.818  102.809 69.927  1.00 27.49  ? 108 SER C OG  1 
ATOM 1557 N N   . GLY B 2 114 ? 97.357  102.404 72.914  1.00 20.98  ? 109 GLY C N   1 
ATOM 1558 C CA  . GLY B 2 114 ? 98.141  101.931 74.031  1.00 13.12  ? 109 GLY C CA  1 
ATOM 1559 C C   . GLY B 2 114 ? 99.586  101.640 73.707  1.00 7.37   ? 109 GLY C C   1 
ATOM 1560 O O   . GLY B 2 114 ? 100.363 101.361 74.626  1.00 9.53   ? 109 GLY C O   1 
ATOM 1561 N N   . ASN B 2 115 ? 99.972  101.703 72.437  1.00 10.50  ? 110 ASN C N   1 
ATOM 1562 C CA  . ASN B 2 115 ? 101.331 101.360 72.049  1.00 15.07  ? 110 ASN C CA  1 
ATOM 1563 C C   . ASN B 2 115 ? 102.316 102.498 72.255  1.00 20.42  ? 110 ASN C C   1 
ATOM 1564 O O   . ASN B 2 115 ? 103.525 102.250 72.228  1.00 30.54  ? 110 ASN C O   1 
ATOM 1565 C CB  . ASN B 2 115 ? 101.363 100.929 70.581  1.00 19.69  ? 110 ASN C CB  1 
ATOM 1566 C CG  . ASN B 2 115 ? 100.371 99.827  70.271  1.00 29.65  ? 110 ASN C CG  1 
ATOM 1567 O OD1 . ASN B 2 115 ? 100.128 98.942  71.090  1.00 27.66  ? 110 ASN C OD1 1 
ATOM 1568 N ND2 . ASN B 2 115 ? 99.789  99.878  69.080  1.00 20.88  ? 110 ASN C ND2 1 
ATOM 1569 N N   . TYR B 2 116 ? 101.840 103.726 72.464  1.00 16.15  ? 111 TYR C N   1 
ATOM 1570 C CA  . TYR B 2 116 ? 102.712 104.889 72.523  1.00 0.00   ? 111 TYR C CA  1 
ATOM 1571 C C   . TYR B 2 116 ? 102.271 105.834 73.628  1.00 0.09   ? 111 TYR C C   1 
ATOM 1572 O O   . TYR B 2 116 ? 101.079 105.999 73.891  1.00 15.06  ? 111 TYR C O   1 
ATOM 1573 C CB  . TYR B 2 116 ? 102.725 105.651 71.190  1.00 14.05  ? 111 TYR C CB  1 
ATOM 1574 C CG  . TYR B 2 116 ? 103.212 104.837 70.019  1.00 15.30  ? 111 TYR C CG  1 
ATOM 1575 C CD1 . TYR B 2 116 ? 104.564 104.753 69.723  1.00 17.12  ? 111 TYR C CD1 1 
ATOM 1576 C CD2 . TYR B 2 116 ? 102.320 104.152 69.210  1.00 18.46  ? 111 TYR C CD2 1 
ATOM 1577 C CE1 . TYR B 2 116 ? 105.012 104.008 68.655  1.00 17.79  ? 111 TYR C CE1 1 
ATOM 1578 C CE2 . TYR B 2 116 ? 102.758 103.405 68.140  1.00 17.66  ? 111 TYR C CE2 1 
ATOM 1579 C CZ  . TYR B 2 116 ? 104.104 103.336 67.867  1.00 18.67  ? 111 TYR C CZ  1 
ATOM 1580 O OH  . TYR B 2 116 ? 104.542 102.592 66.798  1.00 21.90  ? 111 TYR C OH  1 
ATOM 1581 N N   . VAL B 2 117 ? 103.257 106.462 74.261  1.00 14.59  ? 112 VAL C N   1 
ATOM 1582 C CA  . VAL B 2 117 ? 103.043 107.603 75.138  1.00 17.19  ? 112 VAL C CA  1 
ATOM 1583 C C   . VAL B 2 117 ? 103.841 108.776 74.570  1.00 0.75   ? 112 VAL C C   1 
ATOM 1584 O O   . VAL B 2 117 ? 104.658 108.618 73.666  1.00 2.56   ? 112 VAL C O   1 
ATOM 1585 C CB  . VAL B 2 117 ? 103.439 107.312 76.604  1.00 5.23   ? 112 VAL C CB  1 
ATOM 1586 C CG1 . VAL B 2 117 ? 102.569 106.209 77.178  1.00 0.00   ? 112 VAL C CG1 1 
ATOM 1587 C CG2 . VAL B 2 117 ? 104.914 106.941 76.722  1.00 12.77  ? 112 VAL C CG2 1 
ATOM 1588 N N   . ALA B 2 118 ? 103.578 109.966 75.100  1.00 11.12  ? 113 ALA C N   1 
ATOM 1589 C CA  . ALA B 2 118 ? 104.303 111.159 74.691  1.00 7.09   ? 113 ALA C CA  1 
ATOM 1590 C C   . ALA B 2 118 ? 104.509 112.055 75.900  1.00 12.80  ? 113 ALA C C   1 
ATOM 1591 O O   . ALA B 2 118 ? 103.946 111.830 76.973  1.00 12.13  ? 113 ALA C O   1 
ATOM 1592 C CB  . ALA B 2 118 ? 103.569 111.916 73.581  1.00 20.91  ? 113 ALA C CB  1 
ATOM 1593 N N   . CYS B 2 119 ? 105.345 113.072 75.719  1.00 9.97   ? 114 CYS C N   1 
ATOM 1594 C CA  . CYS B 2 119 ? 105.601 114.049 76.765  1.00 11.84  ? 114 CYS C CA  1 
ATOM 1595 C C   . CYS B 2 119 ? 106.295 115.251 76.145  1.00 3.37   ? 114 CYS C C   1 
ATOM 1596 O O   . CYS B 2 119 ? 106.961 115.135 75.115  1.00 0.00   ? 114 CYS C O   1 
ATOM 1597 C CB  . CYS B 2 119 ? 106.448 113.454 77.901  1.00 17.00  ? 114 CYS C CB  1 
ATOM 1598 S SG  . CYS B 2 119 ? 108.054 112.787 77.403  1.00 30.32  ? 114 CYS C SG  1 
ATOM 1599 N N   . GLY B 2 120 ? 106.124 116.409 76.777  1.00 11.80  ? 115 GLY C N   1 
ATOM 1600 C CA  . GLY B 2 120 ? 106.765 117.620 76.310  1.00 3.55   ? 115 GLY C CA  1 
ATOM 1601 C C   . GLY B 2 120 ? 106.911 118.615 77.438  1.00 5.65   ? 115 GLY C C   1 
ATOM 1602 O O   . GLY B 2 120 ? 106.364 118.438 78.525  1.00 13.97  ? 115 GLY C O   1 
ATOM 1603 N N   . GLY B 2 121 ? 107.661 119.674 77.163  1.00 16.06  ? 116 GLY C N   1 
ATOM 1604 C CA  . GLY B 2 121 ? 107.930 120.675 78.172  1.00 21.63  ? 116 GLY C CA  1 
ATOM 1605 C C   . GLY B 2 121 ? 108.790 121.811 77.666  1.00 21.55  ? 116 GLY C C   1 
ATOM 1606 O O   . GLY B 2 121 ? 108.543 122.353 76.587  1.00 14.63  ? 116 GLY C O   1 
ATOM 1607 N N   . LEU B 2 122 ? 109.806 122.180 78.442  1.00 40.46  ? 117 LEU C N   1 
ATOM 1608 C CA  . LEU B 2 122 ? 110.681 123.292 78.094  1.00 44.07  ? 117 LEU C CA  1 
ATOM 1609 C C   . LEU B 2 122 ? 111.762 122.913 77.090  1.00 36.77  ? 117 LEU C C   1 
ATOM 1610 O O   . LEU B 2 122 ? 112.606 123.756 76.769  1.00 40.62  ? 117 LEU C O   1 
ATOM 1611 C CB  . LEU B 2 122 ? 111.328 123.867 79.359  1.00 42.10  ? 117 LEU C CB  1 
ATOM 1612 C CG  . LEU B 2 122 ? 110.380 124.584 80.324  1.00 34.49  ? 117 LEU C CG  1 
ATOM 1613 C CD1 . LEU B 2 122 ? 111.105 124.953 81.602  1.00 35.05  ? 117 LEU C CD1 1 
ATOM 1614 C CD2 . LEU B 2 122 ? 109.776 125.818 79.679  1.00 35.55  ? 117 LEU C CD2 1 
ATOM 1615 N N   . ASP B 2 123 ? 111.767 121.678 76.595  1.00 28.51  ? 118 ASP C N   1 
ATOM 1616 C CA  . ASP B 2 123 ? 112.656 121.304 75.503  1.00 27.76  ? 118 ASP C CA  1 
ATOM 1617 C C   . ASP B 2 123 ? 112.146 121.768 74.146  1.00 36.50  ? 118 ASP C C   1 
ATOM 1618 O O   . ASP B 2 123 ? 112.903 121.718 73.171  1.00 34.61  ? 118 ASP C O   1 
ATOM 1619 C CB  . ASP B 2 123 ? 112.857 119.785 75.485  1.00 35.81  ? 118 ASP C CB  1 
ATOM 1620 C CG  . ASP B 2 123 ? 111.548 119.019 75.401  1.00 35.03  ? 118 ASP C CG  1 
ATOM 1621 O OD1 . ASP B 2 123 ? 110.481 119.660 75.323  1.00 32.58  ? 118 ASP C OD1 1 
ATOM 1622 O OD2 . ASP B 2 123 ? 111.586 117.772 75.411  1.00 31.42  ? 118 ASP C OD2 1 
ATOM 1623 N N   . ASN B 2 124 ? 110.889 122.210 74.063  1.00 32.43  ? 119 ASN C N   1 
ATOM 1624 C CA  . ASN B 2 124 ? 110.210 122.677 72.856  1.00 24.10  ? 119 ASN C CA  1 
ATOM 1625 C C   . ASN B 2 124 ? 109.967 121.557 71.855  1.00 26.22  ? 119 ASN C C   1 
ATOM 1626 O O   . ASN B 2 124 ? 109.491 121.833 70.749  1.00 34.66  ? 119 ASN C O   1 
ATOM 1627 C CB  . ASN B 2 124 ? 110.967 123.815 72.155  1.00 27.94  ? 119 ASN C CB  1 
ATOM 1628 C CG  . ASN B 2 124 ? 110.947 125.110 72.950  1.00 26.51  ? 119 ASN C CG  1 
ATOM 1629 O OD1 . ASN B 2 124 ? 110.804 125.103 74.171  1.00 27.94  ? 119 ASN C OD1 1 
ATOM 1630 N ND2 . ASN B 2 124 ? 111.088 126.230 72.254  1.00 28.30  ? 119 ASN C ND2 1 
ATOM 1631 N N   . ILE B 2 125 ? 110.274 120.311 72.199  1.00 34.21  ? 120 ILE C N   1 
ATOM 1632 C CA  . ILE B 2 125 ? 110.040 119.170 71.327  1.00 35.14  ? 120 ILE C CA  1 
ATOM 1633 C C   . ILE B 2 125 ? 109.050 118.235 72.012  1.00 29.72  ? 120 ILE C C   1 
ATOM 1634 O O   . ILE B 2 125 ? 108.727 118.387 73.190  1.00 31.96  ? 120 ILE C O   1 
ATOM 1635 C CB  . ILE B 2 125 ? 111.350 118.433 70.969  1.00 36.30  ? 120 ILE C CB  1 
ATOM 1636 C CG1 . ILE B 2 125 ? 112.043 117.910 72.227  1.00 31.24  ? 120 ILE C CG1 1 
ATOM 1637 C CG2 . ILE B 2 125 ? 112.289 119.355 70.211  1.00 34.20  ? 120 ILE C CG2 1 
ATOM 1638 C CD1 . ILE B 2 125 ? 113.315 117.155 71.948  1.00 29.77  ? 120 ILE C CD1 1 
ATOM 1639 N N   . CYS B 2 126 ? 108.559 117.259 71.252  1.00 23.99  ? 121 CYS C N   1 
ATOM 1640 C CA  . CYS B 2 126 ? 107.673 116.223 71.766  1.00 21.46  ? 121 CYS C CA  1 
ATOM 1641 C C   . CYS B 2 126 ? 108.278 114.875 71.420  1.00 24.18  ? 121 CYS C C   1 
ATOM 1642 O O   . CYS B 2 126 ? 108.516 114.585 70.244  1.00 27.42  ? 121 CYS C O   1 
ATOM 1643 C CB  . CYS B 2 126 ? 106.267 116.356 71.175  1.00 27.30  ? 121 CYS C CB  1 
ATOM 1644 S SG  . CYS B 2 126 ? 105.095 115.082 71.691  1.00 37.39  ? 121 CYS C SG  1 
ATOM 1645 N N   . SER B 2 127 ? 108.527 114.057 72.439  1.00 23.98  ? 122 SER C N   1 
ATOM 1646 C CA  . SER B 2 127 ? 109.117 112.738 72.262  1.00 24.19  ? 122 SER C CA  1 
ATOM 1647 C C   . SER B 2 127 ? 108.037 111.673 72.359  1.00 22.29  ? 122 SER C C   1 
ATOM 1648 O O   . SER B 2 127 ? 107.141 111.759 73.202  1.00 27.74  ? 122 SER C O   1 
ATOM 1649 C CB  . SER B 2 127 ? 110.201 112.472 73.306  1.00 19.66  ? 122 SER C CB  1 
ATOM 1650 O OG  . SER B 2 127 ? 111.399 113.151 72.981  1.00 32.59  ? 122 SER C OG  1 
ATOM 1651 N N   . ILE B 2 128 ? 108.129 110.674 71.487  1.00 18.69  ? 123 ILE C N   1 
ATOM 1652 C CA  . ILE B 2 128 ? 107.175 109.577 71.421  1.00 18.60  ? 123 ILE C CA  1 
ATOM 1653 C C   . ILE B 2 128 ? 107.928 108.285 71.697  1.00 13.69  ? 123 ILE C C   1 
ATOM 1654 O O   . ILE B 2 128 ? 109.030 108.082 71.176  1.00 13.91  ? 123 ILE C O   1 
ATOM 1655 C CB  . ILE B 2 128 ? 106.464 109.532 70.057  1.00 19.90  ? 123 ILE C CB  1 
ATOM 1656 C CG1 . ILE B 2 128 ? 105.680 110.827 69.840  1.00 20.30  ? 123 ILE C CG1 1 
ATOM 1657 C CG2 . ILE B 2 128 ? 105.537 108.327 69.973  1.00 17.57  ? 123 ILE C CG2 1 
ATOM 1658 C CD1 . ILE B 2 128 ? 105.253 111.063 68.426  1.00 20.50  ? 123 ILE C CD1 1 
ATOM 1659 N N   . TYR B 2 129 ? 107.343 107.427 72.530  1.00 21.75  ? 124 TYR C N   1 
ATOM 1660 C CA  . TYR B 2 129 ? 107.970 106.193 72.980  1.00 24.46  ? 124 TYR C CA  1 
ATOM 1661 C C   . TYR B 2 129 ? 107.114 105.010 72.562  1.00 23.34  ? 124 TYR C C   1 
ATOM 1662 O O   . TYR B 2 129 ? 105.889 105.050 72.699  1.00 28.42  ? 124 TYR C O   1 
ATOM 1663 C CB  . TYR B 2 129 ? 108.155 106.192 74.499  1.00 13.76  ? 124 TYR C CB  1 
ATOM 1664 C CG  . TYR B 2 129 ? 108.911 107.389 75.013  1.00 18.91  ? 124 TYR C CG  1 
ATOM 1665 C CD1 . TYR B 2 129 ? 108.281 108.615 75.175  1.00 12.00  ? 124 TYR C CD1 1 
ATOM 1666 C CD2 . TYR B 2 129 ? 110.254 107.295 75.337  1.00 15.44  ? 124 TYR C CD2 1 
ATOM 1667 C CE1 . TYR B 2 129 ? 108.970 109.712 75.639  1.00 12.68  ? 124 TYR C CE1 1 
ATOM 1668 C CE2 . TYR B 2 129 ? 110.949 108.386 75.806  1.00 19.42  ? 124 TYR C CE2 1 
ATOM 1669 C CZ  . TYR B 2 129 ? 110.304 109.591 75.953  1.00 28.42  ? 124 TYR C CZ  1 
ATOM 1670 O OH  . TYR B 2 129 ? 111.001 110.679 76.418  1.00 25.56  ? 124 TYR C OH  1 
ATOM 1671 N N   . ASN B 2 130 ? 107.759 103.965 72.054  1.00 15.03  ? 125 ASN C N   1 
ATOM 1672 C CA  . ASN B 2 130 ? 107.081 102.724 71.702  1.00 22.33  ? 125 ASN C CA  1 
ATOM 1673 C C   . ASN B 2 130 ? 107.131 101.784 72.901  1.00 12.63  ? 125 ASN C C   1 
ATOM 1674 O O   . ASN B 2 130 ? 108.215 101.427 73.371  1.00 25.69  ? 125 ASN C O   1 
ATOM 1675 C CB  . ASN B 2 130 ? 107.739 102.087 70.477  1.00 28.47  ? 125 ASN C CB  1 
ATOM 1676 C CG  . ASN B 2 130 ? 107.007 100.854 69.993  1.00 27.33  ? 125 ASN C CG  1 
ATOM 1677 O OD1 . ASN B 2 130 ? 105.862 100.608 70.369  1.00 35.07  ? 125 ASN C OD1 1 
ATOM 1678 N ND2 . ASN B 2 130 ? 107.666 100.072 69.150  1.00 11.42  ? 125 ASN C ND2 1 
ATOM 1679 N N   . LEU B 2 131 ? 105.961 101.396 73.403  1.00 0.00   ? 126 LEU C N   1 
ATOM 1680 C CA  . LEU B 2 131 ? 105.880 100.588 74.611  1.00 23.05  ? 126 LEU C CA  1 
ATOM 1681 C C   . LEU B 2 131 ? 105.944 99.092  74.345  1.00 30.38  ? 126 LEU C C   1 
ATOM 1682 O O   . LEU B 2 131 ? 106.092 98.320  75.298  1.00 26.85  ? 126 LEU C O   1 
ATOM 1683 C CB  . LEU B 2 131 ? 104.582 100.891 75.370  1.00 18.44  ? 126 LEU C CB  1 
ATOM 1684 C CG  . LEU B 2 131 ? 104.446 102.249 76.056  1.00 11.86  ? 126 LEU C CG  1 
ATOM 1685 C CD1 . LEU B 2 131 ? 103.063 102.369 76.653  1.00 6.59   ? 126 LEU C CD1 1 
ATOM 1686 C CD2 . LEU B 2 131 ? 105.508 102.451 77.120  1.00 11.73  ? 126 LEU C CD2 1 
ATOM 1687 N N   . LYS B 2 132 ? 105.837 98.660  73.089  1.00 26.80  ? 127 LYS C N   1 
ATOM 1688 C CA  . LYS B 2 132 ? 105.759 97.240  72.746  1.00 18.01  ? 127 LYS C CA  1 
ATOM 1689 C C   . LYS B 2 132 ? 106.793 96.947  71.665  1.00 24.84  ? 127 LYS C C   1 
ATOM 1690 O O   . LYS B 2 132 ? 106.490 96.964  70.471  1.00 29.50  ? 127 LYS C O   1 
ATOM 1691 C CB  . LYS B 2 132 ? 104.350 96.880  72.307  1.00 14.82  ? 127 LYS C CB  1 
ATOM 1692 C CG  . LYS B 2 132 ? 103.314 97.139  73.385  1.00 23.79  ? 127 LYS C CG  1 
ATOM 1693 C CD  . LYS B 2 132 ? 101.907 97.022  72.861  1.00 24.54  ? 127 LYS C CD  1 
ATOM 1694 C CE  . LYS B 2 132 ? 100.897 97.495  73.888  1.00 25.08  ? 127 LYS C CE  1 
ATOM 1695 N NZ  . LYS B 2 132 ? 99.507  97.458  73.358  1.00 20.06  ? 127 LYS C NZ  1 
ATOM 1696 N N   . THR B 2 133 ? 108.014 96.662  72.099  1.00 26.66  ? 128 THR C N   1 
ATOM 1697 C CA  . THR B 2 133 ? 109.110 96.302  71.214  1.00 28.03  ? 128 THR C CA  1 
ATOM 1698 C C   . THR B 2 133 ? 109.376 94.803  71.293  1.00 33.84  ? 128 THR C C   1 
ATOM 1699 O O   . THR B 2 133 ? 108.814 94.085  72.122  1.00 36.17  ? 128 THR C O   1 
ATOM 1700 C CB  . THR B 2 133 ? 110.370 97.090  71.580  1.00 25.82  ? 128 THR C CB  1 
ATOM 1701 O OG1 . THR B 2 133 ? 110.630 96.959  72.981  1.00 28.90  ? 128 THR C OG1 1 
ATOM 1702 C CG2 . THR B 2 133 ? 110.199 98.558  71.239  1.00 29.27  ? 128 THR C CG2 1 
ATOM 1703 N N   . ARG B 2 134 ? 110.249 94.333  70.403  1.00 35.85  ? 129 ARG C N   1 
ATOM 1704 C CA  . ARG B 2 134 ? 110.645 92.931  70.380  1.00 35.87  ? 129 ARG C CA  1 
ATOM 1705 C C   . ARG B 2 134 ? 111.882 92.655  71.223  1.00 36.60  ? 129 ARG C C   1 
ATOM 1706 O O   . ARG B 2 134 ? 112.083 91.512  71.647  1.00 38.18  ? 129 ARG C O   1 
ATOM 1707 C CB  . ARG B 2 134 ? 110.896 92.486  68.935  1.00 44.60  ? 129 ARG C CB  1 
ATOM 1708 C CG  . ARG B 2 134 ? 111.289 91.024  68.767  1.00 43.98  ? 129 ARG C CG  1 
ATOM 1709 C CD  . ARG B 2 134 ? 110.267 90.079  69.376  1.00 40.00  ? 129 ARG C CD  1 
ATOM 1710 N NE  . ARG B 2 134 ? 110.393 88.726  68.846  1.00 40.62  ? 129 ARG C NE  1 
ATOM 1711 C CZ  . ARG B 2 134 ? 109.863 87.644  69.402  1.00 39.62  ? 129 ARG C CZ  1 
ATOM 1712 N NH1 . ARG B 2 134 ? 109.181 87.710  70.533  1.00 37.81  ? 129 ARG C NH1 1 
ATOM 1713 N NH2 . ARG B 2 134 ? 110.024 86.466  68.808  1.00 42.31  ? 129 ARG C NH2 1 
ATOM 1714 N N   . GLU B 2 135 ? 112.710 93.667  71.476  1.00 35.05  ? 130 GLU C N   1 
ATOM 1715 C CA  . GLU B 2 135 ? 113.886 93.507  72.319  1.00 35.31  ? 130 GLU C CA  1 
ATOM 1716 C C   . GLU B 2 135 ? 113.554 93.487  73.804  1.00 33.17  ? 130 GLU C C   1 
ATOM 1717 O O   . GLU B 2 135 ? 114.453 93.253  74.617  1.00 34.91  ? 130 GLU C O   1 
ATOM 1718 C CB  . GLU B 2 135 ? 114.888 94.631  72.041  1.00 37.21  ? 130 GLU C CB  1 
ATOM 1719 C CG  . GLU B 2 135 ? 115.684 94.464  70.755  1.00 36.26  ? 130 GLU C CG  1 
ATOM 1720 C CD  . GLU B 2 135 ? 114.830 94.584  69.508  1.00 41.33  ? 130 GLU C CD  1 
ATOM 1721 O OE1 . GLU B 2 135 ? 113.713 95.135  69.599  1.00 40.48  ? 130 GLU C OE1 1 
ATOM 1722 O OE2 . GLU B 2 135 ? 115.275 94.125  68.435  1.00 39.94  ? 130 GLU C OE2 1 
ATOM 1723 N N   . GLY B 2 136 ? 112.303 93.739  74.177  1.00 35.61  ? 131 GLY C N   1 
ATOM 1724 C CA  . GLY B 2 136 ? 111.902 93.698  75.568  1.00 34.86  ? 131 GLY C CA  1 
ATOM 1725 C C   . GLY B 2 136 ? 112.096 94.982  76.337  1.00 42.11  ? 131 GLY C C   1 
ATOM 1726 O O   . GLY B 2 136 ? 112.046 94.957  77.572  1.00 41.20  ? 131 GLY C O   1 
ATOM 1727 N N   . ASN B 2 137 ? 112.312 96.105  75.653  1.00 37.91  ? 132 ASN C N   1 
ATOM 1728 C CA  . ASN B 2 137 ? 112.528 97.384  76.319  1.00 30.96  ? 132 ASN C CA  1 
ATOM 1729 C C   . ASN B 2 137 ? 111.590 98.445  75.757  1.00 33.33  ? 132 ASN C C   1 
ATOM 1730 O O   . ASN B 2 137 ? 110.678 98.130  74.985  1.00 37.55  ? 132 ASN C O   1 
ATOM 1731 C CB  . ASN B 2 137 ? 113.990 97.817  76.170  1.00 33.63  ? 132 ASN C CB  1 
ATOM 1732 C CG  . ASN B 2 137 ? 114.482 97.732  74.739  1.00 37.14  ? 132 ASN C CG  1 
ATOM 1733 O OD1 . ASN B 2 137 ? 113.699 97.564  73.805  1.00 35.77  ? 132 ASN C OD1 1 
ATOM 1734 N ND2 . ASN B 2 137 ? 115.790 97.848  74.561  1.00 34.58  ? 132 ASN C ND2 1 
ATOM 1735 N N   . VAL B 2 138 ? 111.796 99.700  76.151  1.00 35.79  ? 133 VAL C N   1 
ATOM 1736 C CA  . VAL B 2 138 ? 111.040 100.838 75.643  1.00 32.02  ? 133 VAL C CA  1 
ATOM 1737 C C   . VAL B 2 138 ? 112.013 101.762 74.927  1.00 28.89  ? 133 VAL C C   1 
ATOM 1738 O O   . VAL B 2 138 ? 113.057 102.121 75.484  1.00 31.99  ? 133 VAL C O   1 
ATOM 1739 C CB  . VAL B 2 138 ? 110.304 101.584 76.772  1.00 23.16  ? 133 VAL C CB  1 
ATOM 1740 C CG1 . VAL B 2 138 ? 109.640 102.837 76.241  1.00 33.31  ? 133 VAL C CG1 1 
ATOM 1741 C CG2 . VAL B 2 138 ? 109.278 100.678 77.421  1.00 25.52  ? 133 VAL C CG2 1 
ATOM 1742 N N   . ARG B 2 139 ? 111.672 102.143 73.699  1.00 21.46  ? 134 ARG C N   1 
ATOM 1743 C CA  . ARG B 2 139 ? 112.525 102.969 72.859  1.00 26.15  ? 134 ARG C CA  1 
ATOM 1744 C C   . ARG B 2 139 ? 111.781 104.218 72.410  1.00 21.74  ? 134 ARG C C   1 
ATOM 1745 O O   . ARG B 2 139 ? 110.552 104.225 72.306  1.00 30.71  ? 134 ARG C O   1 
ATOM 1746 C CB  . ARG B 2 139 ? 113.001 102.199 71.623  1.00 26.99  ? 134 ARG C CB  1 
ATOM 1747 C CG  . ARG B 2 139 ? 114.145 101.240 71.875  1.00 26.35  ? 134 ARG C CG  1 
ATOM 1748 C CD  . ARG B 2 139 ? 114.465 100.449 70.622  1.00 30.25  ? 134 ARG C CD  1 
ATOM 1749 N NE  . ARG B 2 139 ? 115.606 99.560  70.800  1.00 29.88  ? 134 ARG C NE  1 
ATOM 1750 C CZ  . ARG B 2 139 ? 116.005 98.664  69.907  1.00 30.02  ? 134 ARG C CZ  1 
ATOM 1751 N NH1 . ARG B 2 139 ? 115.365 98.497  68.761  1.00 29.60  ? 134 ARG C NH1 1 
ATOM 1752 N NH2 . ARG B 2 139 ? 117.071 97.916  70.172  1.00 25.17  ? 134 ARG C NH2 1 
ATOM 1753 N N   . VAL B 2 140 ? 112.544 105.271 72.131  1.00 23.42  ? 135 VAL C N   1 
ATOM 1754 C CA  . VAL B 2 140 ? 111.987 106.500 71.577  1.00 30.59  ? 135 VAL C CA  1 
ATOM 1755 C C   . VAL B 2 140 ? 111.704 106.270 70.099  1.00 24.99  ? 135 VAL C C   1 
ATOM 1756 O O   . VAL B 2 140 ? 112.600 105.900 69.334  1.00 22.17  ? 135 VAL C O   1 
ATOM 1757 C CB  . VAL B 2 140 ? 112.945 107.684 71.774  1.00 26.33  ? 135 VAL C CB  1 
ATOM 1758 C CG1 . VAL B 2 140 ? 112.307 108.971 71.280  1.00 20.50  ? 135 VAL C CG1 1 
ATOM 1759 C CG2 . VAL B 2 140 ? 113.345 107.818 73.226  1.00 30.79  ? 135 VAL C CG2 1 
ATOM 1760 N N   . SER B 2 141 ? 110.456 106.497 69.693  1.00 26.59  ? 136 SER C N   1 
ATOM 1761 C CA  . SER B 2 141 ? 110.074 106.283 68.303  1.00 26.51  ? 136 SER C CA  1 
ATOM 1762 C C   . SER B 2 141 ? 110.400 107.501 67.446  1.00 35.31  ? 136 SER C C   1 
ATOM 1763 O O   . SER B 2 141 ? 110.953 107.365 66.349  1.00 40.56  ? 136 SER C O   1 
ATOM 1764 C CB  . SER B 2 141 ? 108.586 105.950 68.218  1.00 28.75  ? 136 SER C CB  1 
ATOM 1765 O OG  . SER B 2 141 ? 108.169 105.830 66.872  1.00 32.25  ? 136 SER C OG  1 
ATOM 1766 N N   . ARG B 2 142 ? 110.068 108.699 67.925  1.00 32.36  ? 137 ARG C N   1 
ATOM 1767 C CA  . ARG B 2 142 ? 110.313 109.904 67.150  1.00 26.27  ? 137 ARG C CA  1 
ATOM 1768 C C   . ARG B 2 142 ? 110.398 111.108 68.074  1.00 27.52  ? 137 ARG C C   1 
ATOM 1769 O O   . ARG B 2 142 ? 109.780 111.137 69.139  1.00 32.87  ? 137 ARG C O   1 
ATOM 1770 C CB  . ARG B 2 142 ? 109.216 110.126 66.109  1.00 29.76  ? 137 ARG C CB  1 
ATOM 1771 C CG  . ARG B 2 142 ? 109.537 111.233 65.123  1.00 37.32  ? 137 ARG C CG  1 
ATOM 1772 C CD  . ARG B 2 142 ? 108.628 111.190 63.918  1.00 39.68  ? 137 ARG C CD  1 
ATOM 1773 N NE  . ARG B 2 142 ? 108.688 109.903 63.238  1.00 39.22  ? 137 ARG C NE  1 
ATOM 1774 C CZ  . ARG B 2 142 ? 109.635 109.554 62.378  1.00 38.58  ? 137 ARG C CZ  1 
ATOM 1775 N NH1 . ARG B 2 142 ? 110.642 110.363 62.091  1.00 42.71  ? 137 ARG C NH1 1 
ATOM 1776 N NH2 . ARG B 2 142 ? 109.571 108.362 61.792  1.00 35.60  ? 137 ARG C NH2 1 
ATOM 1777 N N   . GLU B 2 143 ? 111.178 112.097 67.645  1.00 36.29  ? 138 GLU C N   1 
ATOM 1778 C CA  . GLU B 2 143 ? 111.244 113.408 68.274  1.00 31.79  ? 138 GLU C CA  1 
ATOM 1779 C C   . GLU B 2 143 ? 110.752 114.444 67.276  1.00 33.02  ? 138 GLU C C   1 
ATOM 1780 O O   . GLU B 2 143 ? 111.171 114.437 66.114  1.00 30.07  ? 138 GLU C O   1 
ATOM 1781 C CB  . GLU B 2 143 ? 112.669 113.742 68.716  1.00 34.82  ? 138 GLU C CB  1 
ATOM 1782 C CG  . GLU B 2 143 ? 113.285 112.730 69.661  1.00 40.29  ? 138 GLU C CG  1 
ATOM 1783 C CD  . GLU B 2 143 ? 114.725 113.053 69.992  1.00 38.06  ? 138 GLU C CD  1 
ATOM 1784 O OE1 . GLU B 2 143 ? 115.356 113.804 69.222  1.00 34.86  ? 138 GLU C OE1 1 
ATOM 1785 O OE2 . GLU B 2 143 ? 115.225 112.560 71.023  1.00 38.32  ? 138 GLU C OE2 1 
ATOM 1786 N N   . LEU B 2 144 ? 109.871 115.330 67.728  1.00 40.43  ? 139 LEU C N   1 
ATOM 1787 C CA  . LEU B 2 144 ? 109.198 116.289 66.863  1.00 41.53  ? 139 LEU C CA  1 
ATOM 1788 C C   . LEU B 2 144 ? 109.741 117.686 67.128  1.00 43.52  ? 139 LEU C C   1 
ATOM 1789 O O   . LEU B 2 144 ? 109.753 118.144 68.275  1.00 49.38  ? 139 LEU C O   1 
ATOM 1790 C CB  . LEU B 2 144 ? 107.687 116.247 67.093  1.00 44.91  ? 139 LEU C CB  1 
ATOM 1791 C CG  . LEU B 2 144 ? 107.046 114.863 66.962  1.00 36.93  ? 139 LEU C CG  1 
ATOM 1792 C CD1 . LEU B 2 144 ? 105.573 114.913 67.332  1.00 33.95  ? 139 LEU C CD1 1 
ATOM 1793 C CD2 . LEU B 2 144 ? 107.229 114.316 65.557  1.00 34.66  ? 139 LEU C CD2 1 
ATOM 1794 N N   . ALA B 2 145 ? 110.186 118.357 66.068  1.00 41.87  ? 140 ALA C N   1 
ATOM 1795 C CA  . ALA B 2 145 ? 110.798 119.673 66.171  1.00 46.93  ? 140 ALA C CA  1 
ATOM 1796 C C   . ALA B 2 145 ? 110.149 120.624 65.176  1.00 50.49  ? 140 ALA C C   1 
ATOM 1797 O O   . ALA B 2 145 ? 109.720 120.217 64.094  1.00 51.61  ? 140 ALA C O   1 
ATOM 1798 C CB  . ALA B 2 145 ? 112.308 119.608 65.916  1.00 49.30  ? 140 ALA C CB  1 
ATOM 1799 N N   . GLY B 2 146 ? 110.105 121.903 65.546  1.00 49.55  ? 141 GLY C N   1 
ATOM 1800 C CA  . GLY B 2 146 ? 109.477 122.915 64.719  1.00 46.80  ? 141 GLY C CA  1 
ATOM 1801 C C   . GLY B 2 146 ? 108.742 123.974 65.517  1.00 50.29  ? 141 GLY C C   1 
ATOM 1802 O O   . GLY B 2 146 ? 108.591 125.108 65.053  1.00 48.02  ? 141 GLY C O   1 
ATOM 1803 N N   . HIS B 2 147 ? 108.280 123.626 66.715  1.00 51.60  ? 142 HIS C N   1 
ATOM 1804 C CA  . HIS B 2 147 ? 107.700 124.623 67.603  1.00 41.84  ? 142 HIS C CA  1 
ATOM 1805 C C   . HIS B 2 147 ? 108.785 125.567 68.104  1.00 47.25  ? 142 HIS C C   1 
ATOM 1806 O O   . HIS B 2 147 ? 109.885 125.139 68.466  1.00 48.39  ? 142 HIS C O   1 
ATOM 1807 C CB  . HIS B 2 147 ? 106.999 123.950 68.785  1.00 39.36  ? 142 HIS C CB  1 
ATOM 1808 C CG  . HIS B 2 147 ? 105.546 123.678 68.550  1.00 47.36  ? 142 HIS C CG  1 
ATOM 1809 N ND1 . HIS B 2 147 ? 104.656 124.660 68.172  1.00 47.04  ? 142 HIS C ND1 1 
ATOM 1810 C CD2 . HIS B 2 147 ? 104.825 122.537 68.651  1.00 49.51  ? 142 HIS C CD2 1 
ATOM 1811 C CE1 . HIS B 2 147 ? 103.451 124.135 68.045  1.00 40.86  ? 142 HIS C CE1 1 
ATOM 1812 N NE2 . HIS B 2 147 ? 103.526 122.848 68.329  1.00 44.28  ? 142 HIS C NE2 1 
ATOM 1813 N N   . THR B 2 148 ? 108.471 126.863 68.118  1.00 46.02  ? 143 THR C N   1 
ATOM 1814 C CA  . THR B 2 148 ? 109.425 127.879 68.549  1.00 43.25  ? 143 THR C CA  1 
ATOM 1815 C C   . THR B 2 148 ? 109.424 128.067 70.062  1.00 42.41  ? 143 THR C C   1 
ATOM 1816 O O   . THR B 2 148 ? 110.481 128.302 70.657  1.00 46.62  ? 143 THR C O   1 
ATOM 1817 C CB  . THR B 2 148 ? 109.122 129.212 67.860  1.00 43.40  ? 143 THR C CB  1 
ATOM 1818 O OG1 . THR B 2 148 ? 109.044 129.013 66.443  1.00 44.63  ? 143 THR C OG1 1 
ATOM 1819 C CG2 . THR B 2 148 ? 110.208 130.233 68.161  1.00 44.19  ? 143 THR C CG2 1 
ATOM 1820 N N   . GLY B 2 149 ? 108.253 127.974 70.692  1.00 36.92  ? 144 GLY C N   1 
ATOM 1821 C CA  . GLY B 2 149 ? 108.127 128.120 72.124  1.00 39.28  ? 144 GLY C CA  1 
ATOM 1822 C C   . GLY B 2 149 ? 107.843 126.787 72.800  1.00 34.98  ? 144 GLY C C   1 
ATOM 1823 O O   . GLY B 2 149 ? 107.613 125.765 72.160  1.00 32.61  ? 144 GLY C O   1 
ATOM 1824 N N   . TYR B 2 150 ? 107.830 126.827 74.130  1.00 35.35  ? 145 TYR C N   1 
ATOM 1825 C CA  . TYR B 2 150 ? 107.698 125.605 74.907  1.00 37.11  ? 145 TYR C CA  1 
ATOM 1826 C C   . TYR B 2 150 ? 106.397 124.891 74.552  1.00 35.70  ? 145 TYR C C   1 
ATOM 1827 O O   . TYR B 2 150 ? 105.572 125.387 73.783  1.00 40.57  ? 145 TYR C O   1 
ATOM 1828 C CB  . TYR B 2 150 ? 107.766 125.903 76.406  1.00 41.88  ? 145 TYR C CB  1 
ATOM 1829 C CG  . TYR B 2 150 ? 106.744 126.893 76.921  1.00 36.30  ? 145 TYR C CG  1 
ATOM 1830 C CD1 . TYR B 2 150 ? 105.451 126.493 77.226  1.00 35.07  ? 145 TYR C CD1 1 
ATOM 1831 C CD2 . TYR B 2 150 ? 107.083 128.221 77.131  1.00 36.22  ? 145 TYR C CD2 1 
ATOM 1832 C CE1 . TYR B 2 150 ? 104.522 127.390 77.705  1.00 37.25  ? 145 TYR C CE1 1 
ATOM 1833 C CE2 . TYR B 2 150 ? 106.160 129.124 77.611  1.00 37.78  ? 145 TYR C CE2 1 
ATOM 1834 C CZ  . TYR B 2 150 ? 104.883 128.703 77.897  1.00 39.05  ? 145 TYR C CZ  1 
ATOM 1835 O OH  . TYR B 2 150 ? 103.961 129.601 78.374  1.00 45.08  ? 145 TYR C OH  1 
ATOM 1836 N N   . LEU B 2 151 ? 106.242 123.686 75.089  1.00 24.38  ? 146 LEU C N   1 
ATOM 1837 C CA  . LEU B 2 151 ? 105.076 122.853 74.834  1.00 18.28  ? 146 LEU C CA  1 
ATOM 1838 C C   . LEU B 2 151 ? 104.198 122.845 76.079  1.00 23.95  ? 146 LEU C C   1 
ATOM 1839 O O   . LEU B 2 151 ? 104.660 122.487 77.167  1.00 24.56  ? 146 LEU C O   1 
ATOM 1840 C CB  . LEU B 2 151 ? 105.504 121.438 74.445  1.00 23.31  ? 146 LEU C CB  1 
ATOM 1841 C CG  . LEU B 2 151 ? 104.458 120.546 73.774  1.00 29.57  ? 146 LEU C CG  1 
ATOM 1842 C CD1 . LEU B 2 151 ? 105.104 119.663 72.726  1.00 19.89  ? 146 LEU C CD1 1 
ATOM 1843 C CD2 . LEU B 2 151 ? 103.723 119.696 74.794  1.00 20.67  ? 146 LEU C CD2 1 
ATOM 1844 N N   . SER B 2 152 ? 102.936 123.241 75.916  1.00 40.32  ? 147 SER C N   1 
ATOM 1845 C CA  . SER B 2 152 ? 101.982 123.331 77.017  1.00 38.87  ? 147 SER C CA  1 
ATOM 1846 C C   . SER B 2 152 ? 101.090 122.103 77.142  1.00 35.82  ? 147 SER C C   1 
ATOM 1847 O O   . SER B 2 152 ? 100.781 121.686 78.261  1.00 37.61  ? 147 SER C O   1 
ATOM 1848 C CB  . SER B 2 152 ? 101.102 124.572 76.851  1.00 31.46  ? 147 SER C CB  1 
ATOM 1849 O OG  . SER B 2 152 ? 101.882 125.752 76.819  1.00 30.03  ? 147 SER C OG  1 
ATOM 1850 N N   . CYS B 2 153 ? 100.647 121.525 76.028  1.00 31.89  ? 148 CYS C N   1 
ATOM 1851 C CA  . CYS B 2 153 ? 99.793  120.349 76.070  1.00 28.13  ? 148 CYS C CA  1 
ATOM 1852 C C   . CYS B 2 153 ? 99.935  119.587 74.761  1.00 33.09  ? 148 CYS C C   1 
ATOM 1853 O O   . CYS B 2 153 ? 100.411 120.121 73.758  1.00 22.34  ? 148 CYS C O   1 
ATOM 1854 C CB  . CYS B 2 153 ? 98.332  120.731 76.323  1.00 36.66  ? 148 CYS C CB  1 
ATOM 1855 S SG  . CYS B 2 153 ? 97.291  119.373 76.920  1.00 54.86  ? 148 CYS C SG  1 
ATOM 1856 N N   . CYS B 2 154 ? 99.523  118.320 74.789  1.00 39.70  ? 149 CYS C N   1 
ATOM 1857 C CA  . CYS B 2 154 ? 99.592  117.452 73.622  1.00 29.07  ? 149 CYS C CA  1 
ATOM 1858 C C   . CYS B 2 154 ? 98.659  116.273 73.841  1.00 20.63  ? 149 CYS C C   1 
ATOM 1859 O O   . CYS B 2 154 ? 98.556  115.761 74.956  1.00 29.47  ? 149 CYS C O   1 
ATOM 1860 C CB  . CYS B 2 154 ? 101.023 116.961 73.362  1.00 31.23  ? 149 CYS C CB  1 
ATOM 1861 S SG  . CYS B 2 154 ? 101.764 115.977 74.689  1.00 9.52   ? 149 CYS C SG  1 
ATOM 1862 N N   . ARG B 2 155 ? 97.973  115.859 72.779  1.00 20.86  ? 150 ARG C N   1 
ATOM 1863 C CA  . ARG B 2 155 ? 97.035  114.750 72.868  1.00 31.07  ? 150 ARG C CA  1 
ATOM 1864 C C   . ARG B 2 155 ? 96.969  114.029 71.531  1.00 32.02  ? 150 ARG C C   1 
ATOM 1865 O O   . ARG B 2 155 ? 96.668  114.647 70.507  1.00 27.64  ? 150 ARG C O   1 
ATOM 1866 C CB  . ARG B 2 155 ? 95.641  115.240 73.274  1.00 31.80  ? 150 ARG C CB  1 
ATOM 1867 C CG  . ARG B 2 155 ? 95.499  115.589 74.754  1.00 33.50  ? 150 ARG C CG  1 
ATOM 1868 C CD  . ARG B 2 155 ? 94.041  115.622 75.163  1.00 36.13  ? 150 ARG C CD  1 
ATOM 1869 N NE  . ARG B 2 155 ? 93.786  116.469 76.321  1.00 36.13  ? 150 ARG C NE  1 
ATOM 1870 C CZ  . ARG B 2 155 ? 92.574  116.788 76.758  1.00 36.57  ? 150 ARG C CZ  1 
ATOM 1871 N NH1 . ARG B 2 155 ? 91.483  116.333 76.162  1.00 36.18  ? 150 ARG C NH1 1 
ATOM 1872 N NH2 . ARG B 2 155 ? 92.453  117.585 77.816  1.00 29.95  ? 150 ARG C NH2 1 
ATOM 1873 N N   . PHE B 2 156 ? 97.239  112.725 71.553  1.00 30.96  ? 151 PHE C N   1 
ATOM 1874 C CA  . PHE B 2 156 ? 97.175  111.920 70.343  1.00 22.94  ? 151 PHE C CA  1 
ATOM 1875 C C   . PHE B 2 156 ? 95.767  111.941 69.765  1.00 29.63  ? 151 PHE C C   1 
ATOM 1876 O O   . PHE B 2 156 ? 94.777  111.923 70.500  1.00 35.98  ? 151 PHE C O   1 
ATOM 1877 C CB  . PHE B 2 156 ? 97.564  110.469 70.638  1.00 24.11  ? 151 PHE C CB  1 
ATOM 1878 C CG  . PHE B 2 156 ? 99.035  110.244 70.858  1.00 24.88  ? 151 PHE C CG  1 
ATOM 1879 C CD1 . PHE B 2 156 ? 99.606  110.450 72.100  1.00 20.25  ? 151 PHE C CD1 1 
ATOM 1880 C CD2 . PHE B 2 156 ? 99.838  109.775 69.831  1.00 22.85  ? 151 PHE C CD2 1 
ATOM 1881 C CE1 . PHE B 2 156 ? 100.949 110.225 72.305  1.00 14.51  ? 151 PHE C CE1 1 
ATOM 1882 C CE2 . PHE B 2 156 ? 101.184 109.547 70.035  1.00 23.57  ? 151 PHE C CE2 1 
ATOM 1883 C CZ  . PHE B 2 156 ? 101.737 109.771 71.272  1.00 20.88  ? 151 PHE C CZ  1 
ATOM 1884 N N   . LEU B 2 157 ? 95.681  111.979 68.438  1.00 40.35  ? 152 LEU C N   1 
ATOM 1885 C CA  . LEU B 2 157 ? 94.447  111.685 67.721  1.00 38.14  ? 152 LEU C CA  1 
ATOM 1886 C C   . LEU B 2 157 ? 94.410  110.250 67.221  1.00 42.28  ? 152 LEU C C   1 
ATOM 1887 O O   . LEU B 2 157 ? 93.347  109.623 67.210  1.00 41.45  ? 152 LEU C O   1 
ATOM 1888 C CB  . LEU B 2 157 ? 94.277  112.632 66.529  1.00 39.93  ? 152 LEU C CB  1 
ATOM 1889 C CG  . LEU B 2 157 ? 93.816  114.063 66.800  1.00 41.89  ? 152 LEU C CG  1 
ATOM 1890 C CD1 . LEU B 2 157 ? 94.901  114.876 67.471  1.00 38.16  ? 152 LEU C CD1 1 
ATOM 1891 C CD2 . LEU B 2 157 ? 93.393  114.710 65.497  1.00 40.26  ? 152 LEU C CD2 1 
ATOM 1892 N N   . ASP B 2 158 ? 95.560  109.726 66.809  1.00 49.03  ? 153 ASP C N   1 
ATOM 1893 C CA  . ASP B 2 158 ? 95.700  108.350 66.361  1.00 46.17  ? 153 ASP C CA  1 
ATOM 1894 C C   . ASP B 2 158 ? 97.122  107.908 66.686  1.00 46.45  ? 153 ASP C C   1 
ATOM 1895 O O   . ASP B 2 158 ? 97.836  108.569 67.445  1.00 46.34  ? 153 ASP C O   1 
ATOM 1896 C CB  . ASP B 2 158 ? 95.377  108.241 64.866  1.00 47.31  ? 153 ASP C CB  1 
ATOM 1897 C CG  . ASP B 2 158 ? 94.900  106.858 64.466  1.00 53.65  ? 153 ASP C CG  1 
ATOM 1898 O OD1 . ASP B 2 158 ? 94.903  105.950 65.323  1.00 51.10  ? 153 ASP C OD1 1 
ATOM 1899 O OD2 . ASP B 2 158 ? 94.520  106.681 63.290  1.00 54.92  ? 153 ASP C OD2 1 
ATOM 1900 N N   . ASP B 2 159 ? 97.541  106.781 66.111  1.00 47.88  ? 154 ASP C N   1 
ATOM 1901 C CA  . ASP B 2 159 ? 98.930  106.364 66.246  1.00 47.03  ? 154 ASP C CA  1 
ATOM 1902 C C   . ASP B 2 159 ? 99.879  107.247 65.451  1.00 46.65  ? 154 ASP C C   1 
ATOM 1903 O O   . ASP B 2 159 ? 101.090 107.195 65.692  1.00 43.76  ? 154 ASP C O   1 
ATOM 1904 C CB  . ASP B 2 159 ? 99.087  104.913 65.795  1.00 46.61  ? 154 ASP C CB  1 
ATOM 1905 C CG  . ASP B 2 159 ? 98.270  103.952 66.630  1.00 49.95  ? 154 ASP C CG  1 
ATOM 1906 O OD1 . ASP B 2 159 ? 97.631  104.403 67.604  1.00 47.78  ? 154 ASP C OD1 1 
ATOM 1907 O OD2 . ASP B 2 159 ? 98.265  102.745 66.313  1.00 51.93  ? 154 ASP C OD2 1 
ATOM 1908 N N   . ASN B 2 160 ? 99.358  108.064 64.531  1.00 49.10  ? 155 ASN C N   1 
ATOM 1909 C CA  . ASN B 2 160 ? 100.180 108.874 63.645  1.00 45.50  ? 155 ASN C CA  1 
ATOM 1910 C C   . ASN B 2 160 ? 99.888  110.366 63.727  1.00 45.21  ? 155 ASN C C   1 
ATOM 1911 O O   . ASN B 2 160 ? 100.686 111.155 63.212  1.00 46.22  ? 155 ASN C O   1 
ATOM 1912 C CB  . ASN B 2 160 ? 99.997  108.416 62.189  1.00 46.20  ? 155 ASN C CB  1 
ATOM 1913 C CG  . ASN B 2 160 ? 101.218 108.683 61.331  1.00 52.78  ? 155 ASN C CG  1 
ATOM 1914 O OD1 . ASN B 2 160 ? 102.355 108.517 61.776  1.00 49.06  ? 155 ASN C OD1 1 
ATOM 1915 N ND2 . ASN B 2 160 ? 100.988 109.098 60.090  1.00 48.40  ? 155 ASN C ND2 1 
ATOM 1916 N N   . GLN B 2 161 ? 98.790  110.776 64.355  1.00 41.08  ? 156 GLN C N   1 
ATOM 1917 C CA  . GLN B 2 161 ? 98.392  112.174 64.438  1.00 41.63  ? 156 GLN C CA  1 
ATOM 1918 C C   . GLN B 2 161 ? 98.391  112.626 65.891  1.00 43.33  ? 156 GLN C C   1 
ATOM 1919 O O   . GLN B 2 161 ? 97.938  111.897 66.777  1.00 39.59  ? 156 GLN C O   1 
ATOM 1920 C CB  . GLN B 2 161 ? 97.002  112.384 63.836  1.00 46.38  ? 156 GLN C CB  1 
ATOM 1921 C CG  . GLN B 2 161 ? 96.904  112.064 62.360  1.00 45.64  ? 156 GLN C CG  1 
ATOM 1922 C CD  . GLN B 2 161 ? 95.501  111.676 61.948  1.00 46.55  ? 156 GLN C CD  1 
ATOM 1923 O OE1 . GLN B 2 161 ? 94.831  110.906 62.636  1.00 45.79  ? 156 GLN C OE1 1 
ATOM 1924 N NE2 . GLN B 2 161 ? 95.045  112.210 60.822  1.00 46.52  ? 156 GLN C NE2 1 
ATOM 1925 N N   . ILE B 2 162 ? 98.896  113.833 66.127  1.00 37.79  ? 157 ILE C N   1 
ATOM 1926 C CA  . ILE B 2 162 ? 98.966  114.396 67.470  1.00 37.80  ? 157 ILE C CA  1 
ATOM 1927 C C   . ILE B 2 162 ? 98.951  115.914 67.353  1.00 33.59  ? 157 ILE C C   1 
ATOM 1928 O O   . ILE B 2 162 ? 99.710  116.491 66.569  1.00 27.13  ? 157 ILE C O   1 
ATOM 1929 C CB  . ILE B 2 162 ? 100.218 113.897 68.227  1.00 33.27  ? 157 ILE C CB  1 
ATOM 1930 C CG1 . ILE B 2 162 ? 100.288 114.511 69.624  1.00 28.41  ? 157 ILE C CG1 1 
ATOM 1931 C CG2 . ILE B 2 162 ? 101.487 114.209 67.446  1.00 30.81  ? 157 ILE C CG2 1 
ATOM 1932 C CD1 . ILE B 2 162 ? 101.232 113.808 70.546  1.00 26.64  ? 157 ILE C CD1 1 
ATOM 1933 N N   . VAL B 2 163 ? 98.081  116.560 68.130  1.00 32.82  ? 158 VAL C N   1 
ATOM 1934 C CA  . VAL B 2 163 ? 97.957  118.015 68.154  1.00 36.24  ? 158 VAL C CA  1 
ATOM 1935 C C   . VAL B 2 163 ? 98.622  118.530 69.421  1.00 24.61  ? 158 VAL C C   1 
ATOM 1936 O O   . VAL B 2 163 ? 98.364  118.020 70.516  1.00 23.43  ? 158 VAL C O   1 
ATOM 1937 C CB  . VAL B 2 163 ? 96.483  118.457 68.087  1.00 35.01  ? 158 VAL C CB  1 
ATOM 1938 C CG1 . VAL B 2 163 ? 96.356  119.947 68.364  1.00 33.70  ? 158 VAL C CG1 1 
ATOM 1939 C CG2 . VAL B 2 163 ? 95.885  118.131 66.729  1.00 31.89  ? 158 VAL C CG2 1 
ATOM 1940 N N   . THR B 2 164 ? 99.478  119.537 69.273  1.00 35.65  ? 159 THR C N   1 
ATOM 1941 C CA  . THR B 2 164 ? 100.218 120.118 70.381  1.00 41.79  ? 159 THR C CA  1 
ATOM 1942 C C   . THR B 2 164 ? 99.928  121.610 70.483  1.00 30.46  ? 159 THR C C   1 
ATOM 1943 O O   . THR B 2 164 ? 99.484  122.247 69.525  1.00 39.82  ? 159 THR C O   1 
ATOM 1944 C CB  . THR B 2 164 ? 101.733 119.895 70.224  1.00 36.52  ? 159 THR C CB  1 
ATOM 1945 O OG1 . THR B 2 164 ? 102.211 120.600 69.072  1.00 38.09  ? 159 THR C OG1 1 
ATOM 1946 C CG2 . THR B 2 164 ? 102.050 118.414 70.079  1.00 24.81  ? 159 THR C CG2 1 
ATOM 1947 N N   . SER B 2 165 ? 100.176 122.159 71.669  1.00 26.55  ? 160 SER C N   1 
ATOM 1948 C CA  . SER B 2 165 ? 100.034 123.581 71.938  1.00 28.42  ? 160 SER C CA  1 
ATOM 1949 C C   . SER B 2 165 ? 101.363 124.134 72.431  1.00 29.84  ? 160 SER C C   1 
ATOM 1950 O O   . SER B 2 165 ? 102.151 123.425 73.059  1.00 13.74  ? 160 SER C O   1 
ATOM 1951 C CB  . SER B 2 165 ? 98.942  123.848 72.979  1.00 35.32  ? 160 SER C CB  1 
ATOM 1952 O OG  . SER B 2 165 ? 99.318  123.364 74.254  1.00 44.18  ? 160 SER C OG  1 
ATOM 1953 N N   . SER B 2 166 ? 101.611 125.408 72.136  1.00 37.91  ? 161 SER C N   1 
ATOM 1954 C CA  . SER B 2 166 ? 102.886 126.033 72.456  1.00 33.31  ? 161 SER C CA  1 
ATOM 1955 C C   . SER B 2 166 ? 102.660 127.466 72.915  1.00 34.09  ? 161 SER C C   1 
ATOM 1956 O O   . SER B 2 166 ? 101.569 128.026 72.784  1.00 31.91  ? 161 SER C O   1 
ATOM 1957 C CB  . SER B 2 166 ? 103.843 126.001 71.255  1.00 29.74  ? 161 SER C CB  1 
ATOM 1958 O OG  . SER B 2 166 ? 103.186 126.385 70.061  1.00 27.92  ? 161 SER C OG  1 
ATOM 1959 N N   . GLY B 2 167 ? 103.715 128.057 73.463  1.00 35.01  ? 162 GLY C N   1 
ATOM 1960 C CA  . GLY B 2 167 ? 103.728 129.457 73.813  1.00 34.70  ? 162 GLY C CA  1 
ATOM 1961 C C   . GLY B 2 167 ? 103.939 130.387 72.644  1.00 39.29  ? 162 GLY C C   1 
ATOM 1962 O O   . GLY B 2 167 ? 104.095 131.595 72.835  1.00 40.28  ? 162 GLY C O   1 
ATOM 1963 N N   . ASP B 2 168 ? 103.953 129.852 71.426  1.00 34.19  ? 163 ASP C N   1 
ATOM 1964 C CA  . ASP B 2 168 ? 104.006 130.653 70.212  1.00 31.79  ? 163 ASP C CA  1 
ATOM 1965 C C   . ASP B 2 168 ? 102.664 131.271 69.855  1.00 40.03  ? 163 ASP C C   1 
ATOM 1966 O O   . ASP B 2 168 ? 102.566 131.939 68.820  1.00 48.17  ? 163 ASP C O   1 
ATOM 1967 C CB  . ASP B 2 168 ? 104.479 129.790 69.045  1.00 39.79  ? 163 ASP C CB  1 
ATOM 1968 C CG  . ASP B 2 168 ? 105.810 129.150 69.305  1.00 37.20  ? 163 ASP C CG  1 
ATOM 1969 O OD1 . ASP B 2 168 ? 106.557 129.667 70.162  1.00 41.57  ? 163 ASP C OD1 1 
ATOM 1970 O OD2 . ASP B 2 168 ? 106.115 128.127 68.657  1.00 30.93  ? 163 ASP C OD2 1 
ATOM 1971 N N   . THR B 2 169 ? 101.637 131.071 70.679  1.00 39.03  ? 164 THR C N   1 
ATOM 1972 C CA  . THR B 2 169 ? 100.283 131.525 70.375  1.00 42.30  ? 164 THR C CA  1 
ATOM 1973 C C   . THR B 2 169 ? 99.706  130.784 69.174  1.00 39.62  ? 164 THR C C   1 
ATOM 1974 O O   . THR B 2 169 ? 98.921  131.343 68.405  1.00 49.23  ? 164 THR C O   1 
ATOM 1975 C CB  . THR B 2 169 ? 100.241 133.037 70.129  1.00 43.83  ? 164 THR C CB  1 
ATOM 1976 O OG1 . THR B 2 169 ? 100.742 133.329 68.819  1.00 43.38  ? 164 THR C OG1 1 
ATOM 1977 C CG2 . THR B 2 169 ? 101.080 133.774 71.161  1.00 43.04  ? 164 THR C CG2 1 
ATOM 1978 N N   . THR B 2 170 ? 100.085 129.521 69.000  1.00 27.99  ? 165 THR C N   1 
ATOM 1979 C CA  . THR B 2 170 ? 99.566  128.722 67.900  1.00 34.51  ? 165 THR C CA  1 
ATOM 1980 C C   . THR B 2 170 ? 99.613  127.249 68.279  1.00 42.11  ? 165 THR C C   1 
ATOM 1981 O O   . THR B 2 170 ? 100.140 126.865 69.325  1.00 39.31  ? 165 THR C O   1 
ATOM 1982 C CB  . THR B 2 170 ? 100.347 128.966 66.602  1.00 34.40  ? 165 THR C CB  1 
ATOM 1983 O OG1 . THR B 2 170 ? 99.874  128.078 65.583  1.00 31.54  ? 165 THR C OG1 1 
ATOM 1984 C CG2 . THR B 2 170 ? 101.836 128.743 66.809  1.00 35.05  ? 165 THR C CG2 1 
ATOM 1985 N N   . CYS B 2 171 ? 99.039  126.428 67.404  1.00 46.71  ? 166 CYS C N   1 
ATOM 1986 C CA  . CYS B 2 171 ? 99.035  124.982 67.551  1.00 35.15  ? 166 CYS C CA  1 
ATOM 1987 C C   . CYS B 2 171 ? 99.327  124.381 66.184  1.00 37.08  ? 166 CYS C C   1 
ATOM 1988 O O   . CYS B 2 171 ? 99.473  125.096 65.190  1.00 38.59  ? 166 CYS C O   1 
ATOM 1989 C CB  . CYS B 2 171 ? 97.700  124.486 68.117  1.00 37.24  ? 166 CYS C CB  1 
ATOM 1990 S SG  . CYS B 2 171 ? 97.182  125.341 69.622  1.00 50.10  ? 166 CYS C SG  1 
ATOM 1991 N N   . ALA B 2 172 ? 99.418  123.056 66.131  1.00 39.06  ? 167 ALA C N   1 
ATOM 1992 C CA  . ALA B 2 172 ? 99.786  122.392 64.892  1.00 37.80  ? 167 ALA C CA  1 
ATOM 1993 C C   . ALA B 2 172 ? 99.348  120.938 64.948  1.00 43.40  ? 167 ALA C C   1 
ATOM 1994 O O   . ALA B 2 172 ? 99.061  120.395 66.017  1.00 41.29  ? 167 ALA C O   1 
ATOM 1995 C CB  . ALA B 2 172 ? 101.294 122.488 64.641  1.00 42.84  ? 167 ALA C CB  1 
ATOM 1996 N N   . LEU B 2 173 ? 99.302  120.321 63.774  1.00 50.98  ? 168 LEU C N   1 
ATOM 1997 C CA  . LEU B 2 173 ? 99.082  118.892 63.627  1.00 47.17  ? 168 LEU C CA  1 
ATOM 1998 C C   . LEU B 2 173 ? 100.350 118.256 63.073  1.00 43.23  ? 168 LEU C C   1 
ATOM 1999 O O   . LEU B 2 173 ? 101.129 118.903 62.368  1.00 45.20  ? 168 LEU C O   1 
ATOM 2000 C CB  . LEU B 2 173 ? 97.894  118.610 62.705  1.00 47.16  ? 168 LEU C CB  1 
ATOM 2001 C CG  . LEU B 2 173 ? 97.472  117.152 62.534  1.00 49.77  ? 168 LEU C CG  1 
ATOM 2002 C CD1 . LEU B 2 173 ? 97.047  116.535 63.852  1.00 45.97  ? 168 LEU C CD1 1 
ATOM 2003 C CD2 . LEU B 2 173 ? 96.351  117.058 61.513  1.00 47.95  ? 168 LEU C CD2 1 
ATOM 2004 N N   . TRP B 2 174 ? 100.561 116.987 63.409  1.00 44.87  ? 169 TRP C N   1 
ATOM 2005 C CA  . TRP B 2 174 ? 101.823 116.317 63.137  1.00 45.25  ? 169 TRP C CA  1 
ATOM 2006 C C   . TRP B 2 174 ? 101.591 114.990 62.432  1.00 49.16  ? 169 TRP C C   1 
ATOM 2007 O O   . TRP B 2 174 ? 100.512 114.398 62.502  1.00 48.83  ? 169 TRP C O   1 
ATOM 2008 C CB  . TRP B 2 174 ? 102.610 116.072 64.425  1.00 49.16  ? 169 TRP C CB  1 
ATOM 2009 C CG  . TRP B 2 174 ? 103.209 117.300 65.002  1.00 50.28  ? 169 TRP C CG  1 
ATOM 2010 C CD1 . TRP B 2 174 ? 102.613 118.183 65.850  1.00 47.63  ? 169 TRP C CD1 1 
ATOM 2011 C CD2 . TRP B 2 174 ? 104.536 117.784 64.784  1.00 44.50  ? 169 TRP C CD2 1 
ATOM 2012 N NE1 . TRP B 2 174 ? 103.488 119.191 66.172  1.00 45.90  ? 169 TRP C NE1 1 
ATOM 2013 C CE2 . TRP B 2 174 ? 104.676 118.967 65.530  1.00 47.23  ? 169 TRP C CE2 1 
ATOM 2014 C CE3 . TRP B 2 174 ? 105.620 117.330 64.031  1.00 40.63  ? 169 TRP C CE3 1 
ATOM 2015 C CZ2 . TRP B 2 174 ? 105.855 119.702 65.544  1.00 47.74  ? 169 TRP C CZ2 1 
ATOM 2016 C CZ3 . TRP B 2 174 ? 106.786 118.061 64.044  1.00 44.54  ? 169 TRP C CZ3 1 
ATOM 2017 C CH2 . TRP B 2 174 ? 106.896 119.233 64.794  1.00 48.25  ? 169 TRP C CH2 1 
ATOM 2018 N N   . ASP B 2 175 ? 102.640 114.534 61.751  1.00 53.78  ? 170 ASP C N   1 
ATOM 2019 C CA  . ASP B 2 175 ? 102.687 113.209 61.142  1.00 50.16  ? 170 ASP C CA  1 
ATOM 2020 C C   . ASP B 2 175 ? 103.912 112.501 61.703  1.00 49.82  ? 170 ASP C C   1 
ATOM 2021 O O   . ASP B 2 175 ? 105.048 112.879 61.398  1.00 46.01  ? 170 ASP C O   1 
ATOM 2022 C CB  . ASP B 2 175 ? 102.747 113.295 59.619  1.00 49.82  ? 170 ASP C CB  1 
ATOM 2023 C CG  . ASP B 2 175 ? 102.522 111.957 58.954  1.00 55.50  ? 170 ASP C CG  1 
ATOM 2024 O OD1 . ASP B 2 175 ? 101.509 111.299 59.268  1.00 55.74  ? 170 ASP C OD1 1 
ATOM 2025 O OD2 . ASP B 2 175 ? 103.355 111.565 58.111  1.00 54.22  ? 170 ASP C OD2 1 
ATOM 2026 N N   . ILE B 2 176 ? 103.682 111.477 62.529  1.00 46.82  ? 171 ILE C N   1 
ATOM 2027 C CA  . ILE B 2 176 ? 104.772 110.854 63.275  1.00 40.85  ? 171 ILE C CA  1 
ATOM 2028 C C   . ILE B 2 176 ? 105.556 109.848 62.448  1.00 45.76  ? 171 ILE C C   1 
ATOM 2029 O O   . ILE B 2 176 ? 106.639 109.426 62.871  1.00 50.77  ? 171 ILE C O   1 
ATOM 2030 C CB  . ILE B 2 176 ? 104.208 110.196 64.550  1.00 41.60  ? 171 ILE C CB  1 
ATOM 2031 C CG1 . ILE B 2 176 ? 103.527 111.244 65.437  1.00 44.24  ? 171 ILE C CG1 1 
ATOM 2032 C CG2 . ILE B 2 176 ? 105.310 109.508 65.336  1.00 38.05  ? 171 ILE C CG2 1 
ATOM 2033 C CD1 . ILE B 2 176 ? 102.494 110.675 66.380  1.00 40.92  ? 171 ILE C CD1 1 
ATOM 2034 N N   . GLU B 2 177 ? 105.059 109.457 61.275  1.00 55.87  ? 172 GLU C N   1 
ATOM 2035 C CA  . GLU B 2 177 ? 105.842 108.605 60.390  1.00 51.44  ? 172 GLU C CA  1 
ATOM 2036 C C   . GLU B 2 177 ? 106.815 109.398 59.530  1.00 52.02  ? 172 GLU C C   1 
ATOM 2037 O O   . GLU B 2 177 ? 107.777 108.818 59.015  1.00 54.27  ? 172 GLU C O   1 
ATOM 2038 C CB  . GLU B 2 177 ? 104.921 107.770 59.492  1.00 54.16  ? 172 GLU C CB  1 
ATOM 2039 C CG  . GLU B 2 177 ? 104.241 108.533 58.369  1.00 56.24  ? 172 GLU C CG  1 
ATOM 2040 C CD  . GLU B 2 177 ? 103.348 107.645 57.522  1.00 59.29  ? 172 GLU C CD  1 
ATOM 2041 O OE1 . GLU B 2 177 ? 103.250 106.436 57.823  1.00 56.99  ? 172 GLU C OE1 1 
ATOM 2042 O OE2 . GLU B 2 177 ? 102.748 108.156 56.554  1.00 58.64  ? 172 GLU C OE2 1 
ATOM 2043 N N   . THR B 2 178 ? 106.592 110.703 59.370  1.00 55.29  ? 173 THR C N   1 
ATOM 2044 C CA  . THR B 2 178 ? 107.527 111.590 58.691  1.00 55.44  ? 173 THR C CA  1 
ATOM 2045 C C   . THR B 2 178 ? 108.153 112.627 59.608  1.00 55.43  ? 173 THR C C   1 
ATOM 2046 O O   . THR B 2 178 ? 109.313 112.987 59.399  1.00 57.07  ? 173 THR C O   1 
ATOM 2047 C CB  . THR B 2 178 ? 106.834 112.328 57.533  1.00 53.64  ? 173 THR C CB  1 
ATOM 2048 O OG1 . THR B 2 178 ? 105.811 113.187 58.050  1.00 56.39  ? 173 THR C OG1 1 
ATOM 2049 C CG2 . THR B 2 178 ? 106.217 111.342 56.556  1.00 52.84  ? 173 THR C CG2 1 
ATOM 2050 N N   . GLY B 2 179 ? 107.428 113.109 60.615  1.00 47.00  ? 174 GLY C N   1 
ATOM 2051 C CA  . GLY B 2 179 ? 107.964 114.089 61.537  1.00 45.80  ? 174 GLY C CA  1 
ATOM 2052 C C   . GLY B 2 179 ? 107.789 115.529 61.118  1.00 47.70  ? 174 GLY C C   1 
ATOM 2053 O O   . GLY B 2 179 ? 108.500 116.397 61.636  1.00 47.82  ? 174 GLY C O   1 
ATOM 2054 N N   . GLN B 2 180 ? 106.866 115.816 60.206  1.00 53.77  ? 175 GLN C N   1 
ATOM 2055 C CA  . GLN B 2 180 ? 106.662 117.155 59.678  1.00 52.39  ? 175 GLN C CA  1 
ATOM 2056 C C   . GLN B 2 180 ? 105.253 117.632 60.006  1.00 51.76  ? 175 GLN C C   1 
ATOM 2057 O O   . GLN B 2 180 ? 104.309 116.839 60.064  1.00 47.93  ? 175 GLN C O   1 
ATOM 2058 C CB  . GLN B 2 180 ? 106.877 117.193 58.156  1.00 50.55  ? 175 GLN C CB  1 
ATOM 2059 C CG  . GLN B 2 180 ? 108.077 116.395 57.664  1.00 50.38  ? 175 GLN C CG  1 
ATOM 2060 C CD  . GLN B 2 180 ? 109.387 116.903 58.227  1.00 55.46  ? 175 GLN C CD  1 
ATOM 2061 O OE1 . GLN B 2 180 ? 109.522 118.081 58.551  1.00 56.42  ? 175 GLN C OE1 1 
ATOM 2062 N NE2 . GLN B 2 180 ? 110.364 116.012 58.347  1.00 52.37  ? 175 GLN C NE2 1 
ATOM 2063 N N   . GLN B 2 181 ? 105.120 118.937 60.221  1.00 48.75  ? 176 GLN C N   1 
ATOM 2064 C CA  . GLN B 2 181 ? 103.814 119.516 60.498  1.00 49.50  ? 176 GLN C CA  1 
ATOM 2065 C C   . GLN B 2 181 ? 102.949 119.521 59.244  1.00 52.30  ? 176 GLN C C   1 
ATOM 2066 O O   . GLN B 2 181 ? 103.443 119.637 58.120  1.00 52.79  ? 176 GLN C O   1 
ATOM 2067 C CB  . GLN B 2 181 ? 103.957 120.944 61.022  1.00 53.05  ? 176 GLN C CB  1 
ATOM 2068 C CG  . GLN B 2 181 ? 104.733 121.066 62.313  1.00 52.90  ? 176 GLN C CG  1 
ATOM 2069 C CD  . GLN B 2 181 ? 104.625 122.448 62.914  1.00 54.00  ? 176 GLN C CD  1 
ATOM 2070 O OE1 . GLN B 2 181 ? 103.922 123.310 62.390  1.00 47.29  ? 176 GLN C OE1 1 
ATOM 2071 N NE2 . GLN B 2 181 ? 105.323 122.669 64.021  1.00 55.48  ? 176 GLN C NE2 1 
ATOM 2072 N N   . THR B 2 182 ? 101.639 119.397 59.450  1.00 48.83  ? 177 THR C N   1 
ATOM 2073 C CA  . THR B 2 182 ? 100.666 119.436 58.368  1.00 45.20  ? 177 THR C CA  1 
ATOM 2074 C C   . THR B 2 182 ? 99.745  120.643 58.424  1.00 49.70  ? 177 THR C C   1 
ATOM 2075 O O   . THR B 2 182 ? 99.254  121.073 57.378  1.00 52.09  ? 177 THR C O   1 
ATOM 2076 C CB  . THR B 2 182 ? 99.808  118.164 58.375  1.00 47.70  ? 177 THR C CB  1 
ATOM 2077 O OG1 . THR B 2 182 ? 98.906  118.197 59.486  1.00 47.67  ? 177 THR C OG1 1 
ATOM 2078 C CG2 . THR B 2 182 ? 100.684 116.928 58.477  1.00 49.38  ? 177 THR C CG2 1 
ATOM 2079 N N   . THR B 2 183 ? 99.494  121.197 59.609  1.00 47.20  ? 178 THR C N   1 
ATOM 2080 C CA  . THR B 2 183 ? 98.623  122.353 59.759  1.00 45.71  ? 178 THR C CA  1 
ATOM 2081 C C   . THR B 2 183 ? 99.202  123.286 60.813  1.00 44.11  ? 178 THR C C   1 
ATOM 2082 O O   . THR B 2 183 ? 100.156 122.951 61.518  1.00 48.21  ? 178 THR C O   1 
ATOM 2083 C CB  . THR B 2 183 ? 97.198  121.945 60.146  1.00 48.86  ? 178 THR C CB  1 
ATOM 2084 O OG1 . THR B 2 183 ? 97.236  121.100 61.301  1.00 51.62  ? 178 THR C OG1 1 
ATOM 2085 C CG2 . THR B 2 183 ? 96.517  121.209 59.004  1.00 44.08  ? 178 THR C CG2 1 
ATOM 2086 N N   . THR B 2 184 ? 98.612  124.476 60.904  1.00 44.88  ? 179 THR C N   1 
ATOM 2087 C CA  . THR B 2 184 ? 98.987  125.462 61.906  1.00 44.06  ? 179 THR C CA  1 
ATOM 2088 C C   . THR B 2 184 ? 97.771  126.330 62.193  1.00 47.13  ? 179 THR C C   1 
ATOM 2089 O O   . THR B 2 184 ? 97.017  126.672 61.279  1.00 46.22  ? 179 THR C O   1 
ATOM 2090 C CB  . THR B 2 184 ? 100.164 126.322 61.440  1.00 42.77  ? 179 THR C CB  1 
ATOM 2091 O OG1 . THR B 2 184 ? 101.266 125.475 61.095  1.00 44.59  ? 179 THR C OG1 1 
ATOM 2092 C CG2 . THR B 2 184 ? 100.599 127.273 62.536  1.00 45.31  ? 179 THR C CG2 1 
ATOM 2093 N N   . PHE B 2 185 ? 97.592  126.687 63.463  1.00 48.03  ? 180 PHE C N   1 
ATOM 2094 C CA  . PHE B 2 185 ? 96.366  127.305 63.962  1.00 45.43  ? 180 PHE C CA  1 
ATOM 2095 C C   . PHE B 2 185 ? 96.673  128.603 64.698  1.00 48.13  ? 180 PHE C C   1 
ATOM 2096 O O   . PHE B 2 185 ? 96.219  128.835 65.820  1.00 47.23  ? 180 PHE C O   1 
ATOM 2097 C CB  . PHE B 2 185 ? 95.619  126.343 64.879  1.00 43.90  ? 180 PHE C CB  1 
ATOM 2098 C CG  . PHE B 2 185 ? 95.375  124.992 64.275  1.00 44.21  ? 180 PHE C CG  1 
ATOM 2099 C CD1 . PHE B 2 185 ? 96.329  123.996 64.369  1.00 46.09  ? 180 PHE C CD1 1 
ATOM 2100 C CD2 . PHE B 2 185 ? 94.188  124.712 63.626  1.00 49.55  ? 180 PHE C CD2 1 
ATOM 2101 C CE1 . PHE B 2 185 ? 96.105  122.751 63.821  1.00 43.11  ? 180 PHE C CE1 1 
ATOM 2102 C CE2 . PHE B 2 185 ? 93.961  123.467 63.082  1.00 49.26  ? 180 PHE C CE2 1 
ATOM 2103 C CZ  . PHE B 2 185 ? 94.920  122.488 63.179  1.00 45.05  ? 180 PHE C CZ  1 
ATOM 2104 N N   . THR B 2 186 ? 97.459  129.471 64.070  1.00 52.53  ? 181 THR C N   1 
ATOM 2105 C CA  . THR B 2 186 ? 97.823  130.733 64.697  1.00 55.18  ? 181 THR C CA  1 
ATOM 2106 C C   . THR B 2 186 ? 96.624  131.678 64.750  1.00 55.91  ? 181 THR C C   1 
ATOM 2107 O O   . THR B 2 186 ? 95.622  131.496 64.055  1.00 55.62  ? 181 THR C O   1 
ATOM 2108 C CB  . THR B 2 186 ? 98.979  131.396 63.946  1.00 55.90  ? 181 THR C CB  1 
ATOM 2109 O OG1 . THR B 2 186 ? 99.384  132.582 64.640  1.00 57.30  ? 181 THR C OG1 1 
ATOM 2110 C CG2 . THR B 2 186 ? 98.573  131.756 62.519  1.00 54.05  ? 181 THR C CG2 1 
ATOM 2111 N N   . GLY B 2 187 ? 96.746  132.708 65.587  1.00 57.02  ? 182 GLY C N   1 
ATOM 2112 C CA  . GLY B 2 187 ? 95.674  133.670 65.766  1.00 56.20  ? 182 GLY C CA  1 
ATOM 2113 C C   . GLY B 2 187 ? 95.509  134.165 67.189  1.00 57.43  ? 182 GLY C C   1 
ATOM 2114 O O   . GLY B 2 187 ? 94.987  135.263 67.405  1.00 54.86  ? 182 GLY C O   1 
ATOM 2115 N N   . HIS B 2 188 ? 95.935  133.374 68.170  1.00 63.04  ? 183 HIS C N   1 
ATOM 2116 C CA  . HIS B 2 188 ? 95.913  133.830 69.551  1.00 56.70  ? 183 HIS C CA  1 
ATOM 2117 C C   . HIS B 2 188 ? 96.983  134.896 69.773  1.00 61.18  ? 183 HIS C C   1 
ATOM 2118 O O   . HIS B 2 188 ? 97.951  135.013 69.017  1.00 63.64  ? 183 HIS C O   1 
ATOM 2119 C CB  . HIS B 2 188 ? 96.141  132.664 70.513  1.00 55.96  ? 183 HIS C CB  1 
ATOM 2120 C CG  . HIS B 2 188 ? 94.983  131.720 70.611  1.00 59.37  ? 183 HIS C CG  1 
ATOM 2121 N ND1 . HIS B 2 188 ? 94.301  131.498 71.788  1.00 58.42  ? 183 HIS C ND1 1 
ATOM 2122 C CD2 . HIS B 2 188 ? 94.390  130.937 69.681  1.00 59.74  ? 183 HIS C CD2 1 
ATOM 2123 C CE1 . HIS B 2 188 ? 93.339  130.619 71.579  1.00 57.59  ? 183 HIS C CE1 1 
ATOM 2124 N NE2 . HIS B 2 188 ? 93.371  130.263 70.308  1.00 61.32  ? 183 HIS C NE2 1 
ATOM 2125 N N   . THR B 2 189 ? 96.798  135.681 70.835  1.00 62.14  ? 184 THR C N   1 
ATOM 2126 C CA  . THR B 2 189 ? 97.717  136.761 71.182  1.00 60.81  ? 184 THR C CA  1 
ATOM 2127 C C   . THR B 2 189 ? 98.716  136.360 72.262  1.00 65.21  ? 184 THR C C   1 
ATOM 2128 O O   . THR B 2 189 ? 99.904  136.676 72.150  1.00 65.89  ? 184 THR C O   1 
ATOM 2129 C CB  . THR B 2 189 ? 96.927  137.992 71.640  1.00 60.68  ? 184 THR C CB  1 
ATOM 2130 O OG1 . THR B 2 189 ? 96.125  138.478 70.557  1.00 63.78  ? 184 THR C OG1 1 
ATOM 2131 C CG2 . THR B 2 189 ? 97.870  139.093 72.105  1.00 61.51  ? 184 THR C CG2 1 
ATOM 2132 N N   . GLY B 2 190 ? 98.257  135.680 73.315  1.00 54.28  ? 185 GLY C N   1 
ATOM 2133 C CA  . GLY B 2 190 ? 99.122  135.231 74.382  1.00 49.39  ? 185 GLY C CA  1 
ATOM 2134 C C   . GLY B 2 190 ? 99.385  133.732 74.326  1.00 52.73  ? 185 GLY C C   1 
ATOM 2135 O O   . GLY B 2 190 ? 98.867  133.004 73.482  1.00 51.88  ? 185 GLY C O   1 
ATOM 2136 N N   . ASP B 2 191 ? 100.210 133.278 75.268  1.00 50.82  ? 186 ASP C N   1 
ATOM 2137 C CA  . ASP B 2 191 ? 100.589 131.873 75.318  1.00 43.54  ? 186 ASP C CA  1 
ATOM 2138 C C   . ASP B 2 191 ? 99.364  130.982 75.462  1.00 43.98  ? 186 ASP C C   1 
ATOM 2139 O O   . ASP B 2 191 ? 98.435  131.290 76.212  1.00 43.42  ? 186 ASP C O   1 
ATOM 2140 C CB  . ASP B 2 191 ? 101.541 131.616 76.488  1.00 44.00  ? 186 ASP C CB  1 
ATOM 2141 C CG  . ASP B 2 191 ? 102.978 131.963 76.164  1.00 48.54  ? 186 ASP C CG  1 
ATOM 2142 O OD1 . ASP B 2 191 ? 103.228 132.535 75.083  1.00 48.63  ? 186 ASP C OD1 1 
ATOM 2143 O OD2 . ASP B 2 191 ? 103.859 131.660 76.994  1.00 43.55  ? 186 ASP C OD2 1 
ATOM 2144 N N   . VAL B 2 192 ? 99.371  129.872 74.733  1.00 48.01  ? 187 VAL C N   1 
ATOM 2145 C CA  . VAL B 2 192 ? 98.383  128.814 74.901  1.00 45.12  ? 187 VAL C CA  1 
ATOM 2146 C C   . VAL B 2 192 ? 98.865  127.891 76.009  1.00 37.99  ? 187 VAL C C   1 
ATOM 2147 O O   . VAL B 2 192 ? 99.986  127.373 75.955  1.00 41.29  ? 187 VAL C O   1 
ATOM 2148 C CB  . VAL B 2 192 ? 98.172  128.043 73.587  1.00 41.31  ? 187 VAL C CB  1 
ATOM 2149 C CG1 . VAL B 2 192 ? 97.148  126.932 73.769  1.00 39.47  ? 187 VAL C CG1 1 
ATOM 2150 C CG2 . VAL B 2 192 ? 97.741  128.993 72.481  1.00 38.12  ? 187 VAL C CG2 1 
ATOM 2151 N N   . MET B 2 193 ? 98.020  127.688 77.022  1.00 35.27  ? 188 MET C N   1 
ATOM 2152 C CA  . MET B 2 193 ? 98.372  126.875 78.176  1.00 41.21  ? 188 MET C CA  1 
ATOM 2153 C C   . MET B 2 193 ? 97.517  125.628 78.350  1.00 30.89  ? 188 MET C C   1 
ATOM 2154 O O   . MET B 2 193 ? 97.905  124.747 79.122  1.00 24.42  ? 188 MET C O   1 
ATOM 2155 C CB  . MET B 2 193 ? 98.284  127.711 79.462  1.00 38.56  ? 188 MET C CB  1 
ATOM 2156 C CG  . MET B 2 193 ? 99.562  128.464 79.800  1.00 35.93  ? 188 MET C CG  1 
ATOM 2157 S SD  . MET B 2 193 ? 100.899 127.361 80.294  1.00 38.53  ? 188 MET C SD  1 
ATOM 2158 C CE  . MET B 2 193 ? 102.132 128.538 80.832  1.00 32.79  ? 188 MET C CE  1 
ATOM 2159 N N   . SER B 2 194 ? 96.382  125.524 77.666  1.00 39.66  ? 189 SER C N   1 
ATOM 2160 C CA  . SER B 2 194 ? 95.494  124.381 77.792  1.00 41.68  ? 189 SER C CA  1 
ATOM 2161 C C   . SER B 2 194 ? 95.125  123.870 76.406  1.00 43.41  ? 189 SER C C   1 
ATOM 2162 O O   . SER B 2 194 ? 95.447  124.479 75.384  1.00 43.48  ? 189 SER C O   1 
ATOM 2163 C CB  . SER B 2 194 ? 94.229  124.735 78.584  1.00 34.92  ? 189 SER C CB  1 
ATOM 2164 O OG  . SER B 2 194 ? 93.431  125.670 77.886  1.00 38.06  ? 189 SER C OG  1 
ATOM 2165 N N   . LEU B 2 195 ? 94.437  122.731 76.387  1.00 44.74  ? 190 LEU C N   1 
ATOM 2166 C CA  . LEU B 2 195 ? 94.126  122.026 75.154  1.00 37.47  ? 190 LEU C CA  1 
ATOM 2167 C C   . LEU B 2 195 ? 93.138  120.919 75.472  1.00 30.50  ? 190 LEU C C   1 
ATOM 2168 O O   . LEU B 2 195 ? 93.249  120.269 76.512  1.00 31.40  ? 190 LEU C O   1 
ATOM 2169 C CB  . LEU B 2 195 ? 95.403  121.453 74.528  1.00 44.07  ? 190 LEU C CB  1 
ATOM 2170 C CG  . LEU B 2 195 ? 95.324  120.556 73.296  1.00 38.43  ? 190 LEU C CG  1 
ATOM 2171 C CD1 . LEU B 2 195 ? 96.541  120.804 72.423  1.00 31.29  ? 190 LEU C CD1 1 
ATOM 2172 C CD2 . LEU B 2 195 ? 95.234  119.081 73.666  1.00 34.38  ? 190 LEU C CD2 1 
ATOM 2173 N N   . SER B 2 196 ? 92.178  120.708 74.575  1.00 28.79  ? 191 SER C N   1 
ATOM 2174 C CA  . SER B 2 196 ? 91.112  119.745 74.828  1.00 33.33  ? 191 SER C CA  1 
ATOM 2175 C C   . SER B 2 196 ? 90.560  119.275 73.490  1.00 35.79  ? 191 SER C C   1 
ATOM 2176 O O   . SER B 2 196 ? 89.930  120.058 72.773  1.00 28.81  ? 191 SER C O   1 
ATOM 2177 C CB  . SER B 2 196 ? 90.018  120.368 75.685  1.00 26.79  ? 191 SER C CB  1 
ATOM 2178 O OG  . SER B 2 196 ? 89.045  119.407 76.052  1.00 28.76  ? 191 SER C OG  1 
ATOM 2179 N N   . LEU B 2 197 ? 90.791  118.006 73.167  1.00 37.75  ? 192 LEU C N   1 
ATOM 2180 C CA  . LEU B 2 197 ? 90.235  117.406 71.965  1.00 33.01  ? 192 LEU C CA  1 
ATOM 2181 C C   . LEU B 2 197 ? 88.775  117.039 72.177  1.00 38.92  ? 192 LEU C C   1 
ATOM 2182 O O   . LEU B 2 197 ? 88.383  116.589 73.255  1.00 48.01  ? 192 LEU C O   1 
ATOM 2183 C CB  . LEU B 2 197 ? 91.018  116.155 71.577  1.00 42.33  ? 192 LEU C CB  1 
ATOM 2184 C CG  . LEU B 2 197 ? 92.282  116.331 70.742  1.00 41.08  ? 192 LEU C CG  1 
ATOM 2185 C CD1 . LEU B 2 197 ? 93.283  117.212 71.455  1.00 40.18  ? 192 LEU C CD1 1 
ATOM 2186 C CD2 . LEU B 2 197 ? 92.874  114.972 70.434  1.00 38.50  ? 192 LEU C CD2 1 
ATOM 2187 N N   . ALA B 2 198 ? 87.976  117.219 71.133  1.00 46.58  ? 193 ALA C N   1 
ATOM 2188 C CA  . ALA B 2 198 ? 86.576  116.846 71.190  1.00 49.95  ? 193 ALA C CA  1 
ATOM 2189 C C   . ALA B 2 198 ? 86.446  115.328 71.283  1.00 54.92  ? 193 ALA C C   1 
ATOM 2190 O O   . ALA B 2 198 ? 87.388  114.596 70.972  1.00 57.68  ? 193 ALA C O   1 
ATOM 2191 C CB  . ALA B 2 198 ? 85.841  117.363 69.957  1.00 50.61  ? 193 ALA C CB  1 
ATOM 2192 N N   . PRO B 2 199 ? 85.291  114.826 71.726  1.00 60.50  ? 194 PRO C N   1 
ATOM 2193 C CA  . PRO B 2 199 ? 85.110  113.367 71.754  1.00 63.24  ? 194 PRO C CA  1 
ATOM 2194 C C   . PRO B 2 199 ? 85.320  112.715 70.399  1.00 64.84  ? 194 PRO C C   1 
ATOM 2195 O O   . PRO B 2 199 ? 85.814  111.583 70.337  1.00 64.00  ? 194 PRO C O   1 
ATOM 2196 C CB  . PRO B 2 199 ? 83.667  113.196 72.254  1.00 60.95  ? 194 PRO C CB  1 
ATOM 2197 C CG  . PRO B 2 199 ? 83.032  114.538 72.123  1.00 62.39  ? 194 PRO C CG  1 
ATOM 2198 C CD  . PRO B 2 199 ? 84.130  115.528 72.293  1.00 61.61  ? 194 PRO C CD  1 
ATOM 2199 N N   . ASP B 2 200 ? 84.960  113.394 69.311  1.00 69.70  ? 195 ASP C N   1 
ATOM 2200 C CA  . ASP B 2 200 ? 85.254  112.914 67.968  1.00 70.65  ? 195 ASP C CA  1 
ATOM 2201 C C   . ASP B 2 200 ? 86.622  113.359 67.468  1.00 70.92  ? 195 ASP C C   1 
ATOM 2202 O O   . ASP B 2 200 ? 87.060  112.892 66.412  1.00 71.25  ? 195 ASP C O   1 
ATOM 2203 C CB  . ASP B 2 200 ? 84.180  113.398 66.987  1.00 72.01  ? 195 ASP C CB  1 
ATOM 2204 C CG  . ASP B 2 200 ? 82.836  112.740 67.224  1.00 71.69  ? 195 ASP C CG  1 
ATOM 2205 O OD1 . ASP B 2 200 ? 82.810  111.571 67.661  1.00 71.99  ? 195 ASP C OD1 1 
ATOM 2206 O OD2 . ASP B 2 200 ? 81.802  113.394 66.971  1.00 69.67  ? 195 ASP C OD2 1 
ATOM 2207 N N   . THR B 2 201 ? 87.304  114.239 68.199  1.00 67.02  ? 196 THR C N   1 
ATOM 2208 C CA  . THR B 2 201 ? 88.621  114.755 67.830  1.00 67.55  ? 196 THR C CA  1 
ATOM 2209 C C   . THR B 2 201 ? 88.602  115.489 66.494  1.00 67.32  ? 196 THR C C   1 
ATOM 2210 O O   . THR B 2 201 ? 89.650  115.655 65.860  1.00 66.98  ? 196 THR C O   1 
ATOM 2211 C CB  . THR B 2 201 ? 89.669  113.637 67.799  1.00 66.45  ? 196 THR C CB  1 
ATOM 2212 O OG1 . THR B 2 201 ? 89.294  112.647 66.832  1.00 64.54  ? 196 THR C OG1 1 
ATOM 2213 C CG2 . THR B 2 201 ? 89.795  112.986 69.169  1.00 66.35  ? 196 THR C CG2 1 
ATOM 2214 N N   . ARG B 2 202 ? 87.426  115.943 66.056  1.00 65.19  ? 197 ARG C N   1 
ATOM 2215 C CA  . ARG B 2 202 ? 87.311  116.774 64.863  1.00 67.29  ? 197 ARG C CA  1 
ATOM 2216 C C   . ARG B 2 202 ? 87.379  118.256 65.209  1.00 67.93  ? 197 ARG C C   1 
ATOM 2217 O O   . ARG B 2 202 ? 88.104  119.017 64.562  1.00 65.57  ? 197 ARG C O   1 
ATOM 2218 C CB  . ARG B 2 202 ? 86.003  116.471 64.129  1.00 68.69  ? 197 ARG C CB  1 
ATOM 2219 C CG  . ARG B 2 202 ? 86.091  115.319 63.140  1.00 67.62  ? 197 ARG C CG  1 
ATOM 2220 C CD  . ARG B 2 202 ? 84.852  115.241 62.255  1.00 68.38  ? 197 ARG C CD  1 
ATOM 2221 N NE  . ARG B 2 202 ? 84.566  116.511 61.595  1.00 70.40  ? 197 ARG C NE  1 
ATOM 2222 C CZ  . ARG B 2 202 ? 85.179  116.950 60.503  1.00 70.48  ? 197 ARG C CZ  1 
ATOM 2223 N NH1 . ARG B 2 202 ? 86.115  116.237 59.899  1.00 69.02  ? 197 ARG C NH1 1 
ATOM 2224 N NH2 . ARG B 2 202 ? 84.844  118.137 60.006  1.00 67.61  ? 197 ARG C NH2 1 
ATOM 2225 N N   . LEU B 2 203 ? 86.626  118.678 66.219  1.00 61.52  ? 198 LEU C N   1 
ATOM 2226 C CA  . LEU B 2 203 ? 86.691  120.039 66.722  1.00 57.91  ? 198 LEU C CA  1 
ATOM 2227 C C   . LEU B 2 203 ? 87.721  120.131 67.841  1.00 54.79  ? 198 LEU C C   1 
ATOM 2228 O O   . LEU B 2 203 ? 88.215  119.125 68.352  1.00 53.23  ? 198 LEU C O   1 
ATOM 2229 C CB  . LEU B 2 203 ? 85.318  120.495 67.212  1.00 57.81  ? 198 LEU C CB  1 
ATOM 2230 C CG  . LEU B 2 203 ? 84.273  120.820 66.143  1.00 58.23  ? 198 LEU C CG  1 
ATOM 2231 C CD1 . LEU B 2 203 ? 82.974  121.242 66.808  1.00 57.74  ? 198 LEU C CD1 1 
ATOM 2232 C CD2 . LEU B 2 203 ? 84.768  121.901 65.190  1.00 59.48  ? 198 LEU C CD2 1 
ATOM 2233 N N   . PHE B 2 204 ? 88.043  121.362 68.228  1.00 47.30  ? 199 PHE C N   1 
ATOM 2234 C CA  . PHE B 2 204 ? 89.196  121.586 69.092  1.00 44.89  ? 199 PHE C CA  1 
ATOM 2235 C C   . PHE B 2 204 ? 89.116  122.985 69.684  1.00 40.53  ? 199 PHE C C   1 
ATOM 2236 O O   . PHE B 2 204 ? 89.040  123.965 68.940  1.00 36.47  ? 199 PHE C O   1 
ATOM 2237 C CB  . PHE B 2 204 ? 90.476  121.392 68.276  1.00 48.52  ? 199 PHE C CB  1 
ATOM 2238 C CG  . PHE B 2 204 ? 91.734  121.557 69.055  1.00 42.46  ? 199 PHE C CG  1 
ATOM 2239 C CD1 . PHE B 2 204 ? 92.324  122.799 69.180  1.00 48.29  ? 199 PHE C CD1 1 
ATOM 2240 C CD2 . PHE B 2 204 ? 92.344  120.470 69.638  1.00 37.42  ? 199 PHE C CD2 1 
ATOM 2241 C CE1 . PHE B 2 204 ? 93.486  122.955 69.887  1.00 48.95  ? 199 PHE C CE1 1 
ATOM 2242 C CE2 . PHE B 2 204 ? 93.512  120.624 70.345  1.00 40.74  ? 199 PHE C CE2 1 
ATOM 2243 C CZ  . PHE B 2 204 ? 94.082  121.871 70.465  1.00 41.95  ? 199 PHE C CZ  1 
ATOM 2244 N N   . VAL B 2 205 ? 89.128  123.079 71.013  1.00 45.04  ? 200 VAL C N   1 
ATOM 2245 C CA  . VAL B 2 205 ? 89.121  124.352 71.724  1.00 45.29  ? 200 VAL C CA  1 
ATOM 2246 C C   . VAL B 2 205 ? 90.345  124.399 72.626  1.00 33.84  ? 200 VAL C C   1 
ATOM 2247 O O   . VAL B 2 205 ? 90.799  123.372 73.139  1.00 36.61  ? 200 VAL C O   1 
ATOM 2248 C CB  . VAL B 2 205 ? 87.828  124.561 72.551  1.00 40.54  ? 200 VAL C CB  1 
ATOM 2249 C CG1 . VAL B 2 205 ? 87.785  125.957 73.145  1.00 34.79  ? 200 VAL C CG1 1 
ATOM 2250 C CG2 . VAL B 2 205 ? 86.594  124.321 71.698  1.00 43.18  ? 200 VAL C CG2 1 
ATOM 2251 N N   . SER B 2 206 ? 90.884  125.599 72.816  1.00 37.05  ? 201 SER C N   1 
ATOM 2252 C CA  . SER B 2 206 ? 92.072  125.773 73.637  1.00 38.58  ? 201 SER C CA  1 
ATOM 2253 C C   . SER B 2 206 ? 92.088  127.184 74.209  1.00 45.74  ? 201 SER C C   1 
ATOM 2254 O O   . SER B 2 206 ? 91.688  128.137 73.538  1.00 42.45  ? 201 SER C O   1 
ATOM 2255 C CB  . SER B 2 206 ? 93.344  125.510 72.825  1.00 42.93  ? 201 SER C CB  1 
ATOM 2256 O OG  . SER B 2 206 ? 94.482  125.417 73.663  1.00 45.35  ? 201 SER C OG  1 
ATOM 2257 N N   . GLY B 2 207 ? 92.559  127.304 75.453  1.00 46.88  ? 202 GLY C N   1 
ATOM 2258 C CA  . GLY B 2 207 ? 92.638  128.577 76.131  1.00 41.00  ? 202 GLY C CA  1 
ATOM 2259 C C   . GLY B 2 207 ? 94.031  129.172 76.067  1.00 40.66  ? 202 GLY C C   1 
ATOM 2260 O O   . GLY B 2 207 ? 95.007  128.478 75.802  1.00 37.07  ? 202 GLY C O   1 
ATOM 2261 N N   . ALA B 2 208 ? 94.113  130.476 76.326  1.00 45.07  ? 203 ALA C N   1 
ATOM 2262 C CA  . ALA B 2 208 ? 95.345  131.228 76.142  1.00 45.83  ? 203 ALA C CA  1 
ATOM 2263 C C   . ALA B 2 208 ? 95.587  132.166 77.317  1.00 47.82  ? 203 ALA C C   1 
ATOM 2264 O O   . ALA B 2 208 ? 94.721  132.375 78.169  1.00 50.20  ? 203 ALA C O   1 
ATOM 2265 C CB  . ALA B 2 208 ? 95.309  132.026 74.837  1.00 47.45  ? 203 ALA C CB  1 
ATOM 2266 N N   . CYS B 2 209 ? 96.797  132.732 77.349  1.00 56.69  ? 204 CYS C N   1 
ATOM 2267 C CA  . CYS B 2 209 ? 97.114  133.754 78.341  1.00 59.82  ? 204 CYS C CA  1 
ATOM 2268 C C   . CYS B 2 209 ? 96.186  134.953 78.198  1.00 53.26  ? 204 CYS C C   1 
ATOM 2269 O O   . CYS B 2 209 ? 95.689  135.486 79.196  1.00 51.15  ? 204 CYS C O   1 
ATOM 2270 C CB  . CYS B 2 209 ? 98.575  134.184 78.201  1.00 57.03  ? 204 CYS C CB  1 
ATOM 2271 S SG  . CYS B 2 209 ? 99.025  135.642 79.171  1.00 67.39  ? 204 CYS C SG  1 
ATOM 2272 N N   . ASP B 2 210 ? 95.946  135.397 76.969  1.00 51.52  ? 205 ASP C N   1 
ATOM 2273 C CA  . ASP B 2 210 ? 94.830  136.296 76.725  1.00 58.91  ? 205 ASP C CA  1 
ATOM 2274 C C   . ASP B 2 210 ? 93.532  135.566 77.037  1.00 59.13  ? 205 ASP C C   1 
ATOM 2275 O O   . ASP B 2 210 ? 93.314  134.441 76.581  1.00 58.56  ? 205 ASP C O   1 
ATOM 2276 C CB  . ASP B 2 210 ? 94.835  136.783 75.275  1.00 54.12  ? 205 ASP C CB  1 
ATOM 2277 C CG  . ASP B 2 210 ? 94.877  135.643 74.278  1.00 56.76  ? 205 ASP C CG  1 
ATOM 2278 O OD1 . ASP B 2 210 ? 95.878  134.901 74.273  1.00 58.14  ? 205 ASP C OD1 1 
ATOM 2279 O OD2 . ASP B 2 210 ? 93.909  135.484 73.506  1.00 56.55  ? 205 ASP C OD2 1 
ATOM 2280 N N   . ALA B 2 211 ? 92.661  136.214 77.804  1.00 53.86  ? 206 ALA C N   1 
ATOM 2281 C CA  . ALA B 2 211 ? 91.477  135.548 78.326  1.00 53.15  ? 206 ALA C CA  1 
ATOM 2282 C C   . ALA B 2 211 ? 90.447  135.312 77.229  1.00 55.66  ? 206 ALA C C   1 
ATOM 2283 O O   . ALA B 2 211 ? 89.412  135.985 77.186  1.00 56.89  ? 206 ALA C O   1 
ATOM 2284 C CB  . ALA B 2 211 ? 90.866  136.374 79.457  1.00 56.85  ? 206 ALA C CB  1 
ATOM 2285 N N   . SER B 2 212 ? 90.721  134.358 76.341  1.00 53.05  ? 207 SER C N   1 
ATOM 2286 C CA  . SER B 2 212 ? 89.775  133.983 75.302  1.00 49.45  ? 207 SER C CA  1 
ATOM 2287 C C   . SER B 2 212 ? 90.044  132.546 74.884  1.00 56.51  ? 207 SER C C   1 
ATOM 2288 O O   . SER B 2 212 ? 91.178  132.063 74.957  1.00 57.90  ? 207 SER C O   1 
ATOM 2289 C CB  . SER B 2 212 ? 89.864  134.914 74.088  1.00 49.64  ? 207 SER C CB  1 
ATOM 2290 O OG  . SER B 2 212 ? 91.118  134.795 73.443  1.00 57.26  ? 207 SER C OG  1 
ATOM 2291 N N   . ALA B 2 213 ? 88.987  131.865 74.452  1.00 49.80  ? 208 ALA C N   1 
ATOM 2292 C CA  . ALA B 2 213 ? 89.064  130.499 73.959  1.00 48.19  ? 208 ALA C CA  1 
ATOM 2293 C C   . ALA B 2 213 ? 88.513  130.455 72.543  1.00 47.97  ? 208 ALA C C   1 
ATOM 2294 O O   . ALA B 2 213 ? 87.509  131.103 72.241  1.00 52.46  ? 208 ALA C O   1 
ATOM 2295 C CB  . ALA B 2 213 ? 88.285  129.538 74.858  1.00 48.95  ? 208 ALA C CB  1 
ATOM 2296 N N   . LYS B 2 214 ? 89.174  129.691 71.677  1.00 48.26  ? 209 LYS C N   1 
ATOM 2297 C CA  . LYS B 2 214 ? 88.840  129.645 70.262  1.00 48.92  ? 209 LYS C CA  1 
ATOM 2298 C C   . LYS B 2 214 ? 88.673  128.204 69.806  1.00 51.11  ? 209 LYS C C   1 
ATOM 2299 O O   . LYS B 2 214 ? 89.437  127.323 70.204  1.00 52.51  ? 209 LYS C O   1 
ATOM 2300 C CB  . LYS B 2 214 ? 89.915  130.338 69.425  1.00 46.68  ? 209 LYS C CB  1 
ATOM 2301 C CG  . LYS B 2 214 ? 89.888  131.846 69.540  1.00 50.36  ? 209 LYS C CG  1 
ATOM 2302 C CD  . LYS B 2 214 ? 91.079  132.488 68.859  1.00 50.82  ? 209 LYS C CD  1 
ATOM 2303 C CE  . LYS B 2 214 ? 90.962  134.005 68.862  1.00 51.51  ? 209 LYS C CE  1 
ATOM 2304 N NZ  . LYS B 2 214 ? 90.770  134.554 70.232  1.00 47.60  ? 209 LYS C NZ  1 
ATOM 2305 N N   . LEU B 2 215 ? 87.673  127.983 68.961  1.00 54.47  ? 210 LEU C N   1 
ATOM 2306 C CA  . LEU B 2 215 ? 87.345  126.662 68.446  1.00 51.05  ? 210 LEU C CA  1 
ATOM 2307 C C   . LEU B 2 215 ? 88.046  126.461 67.107  1.00 53.54  ? 210 LEU C C   1 
ATOM 2308 O O   . LEU B 2 215 ? 87.829  127.232 66.166  1.00 51.18  ? 210 LEU C O   1 
ATOM 2309 C CB  . LEU B 2 215 ? 85.830  126.524 68.298  1.00 51.02  ? 210 LEU C CB  1 
ATOM 2310 C CG  . LEU B 2 215 ? 85.263  125.274 67.633  1.00 53.88  ? 210 LEU C CG  1 
ATOM 2311 C CD1 . LEU B 2 215 ? 85.410  124.072 68.537  1.00 50.29  ? 210 LEU C CD1 1 
ATOM 2312 C CD2 . LEU B 2 215 ? 83.803  125.495 67.267  1.00 53.64  ? 210 LEU C CD2 1 
ATOM 2313 N N   . TRP B 2 216 ? 88.880  125.427 67.023  1.00 57.77  ? 211 TRP C N   1 
ATOM 2314 C CA  . TRP B 2 216 ? 89.677  125.142 65.840  1.00 52.78  ? 211 TRP C CA  1 
ATOM 2315 C C   . TRP B 2 216 ? 89.209  123.857 65.174  1.00 53.45  ? 211 TRP C C   1 
ATOM 2316 O O   . TRP B 2 216 ? 88.741  122.926 65.834  1.00 52.21  ? 211 TRP C O   1 
ATOM 2317 C CB  . TRP B 2 216 ? 91.157  125.016 66.191  1.00 49.51  ? 211 TRP C CB  1 
ATOM 2318 C CG  . TRP B 2 216 ? 91.710  126.241 66.800  1.00 51.12  ? 211 TRP C CG  1 
ATOM 2319 C CD1 . TRP B 2 216 ? 91.916  126.474 68.122  1.00 51.90  ? 211 TRP C CD1 1 
ATOM 2320 C CD2 . TRP B 2 216 ? 92.130  127.422 66.111  1.00 53.22  ? 211 TRP C CD2 1 
ATOM 2321 N NE1 . TRP B 2 216 ? 92.441  127.727 68.303  1.00 60.04  ? 211 TRP C NE1 1 
ATOM 2322 C CE2 . TRP B 2 216 ? 92.582  128.331 67.081  1.00 55.65  ? 211 TRP C CE2 1 
ATOM 2323 C CE3 . TRP B 2 216 ? 92.171  127.798 64.766  1.00 54.95  ? 211 TRP C CE3 1 
ATOM 2324 C CZ2 . TRP B 2 216 ? 93.069  129.593 66.752  1.00 50.78  ? 211 TRP C CZ2 1 
ATOM 2325 C CZ3 . TRP B 2 216 ? 92.656  129.046 64.442  1.00 52.44  ? 211 TRP C CZ3 1 
ATOM 2326 C CH2 . TRP B 2 216 ? 93.096  129.930 65.428  1.00 51.48  ? 211 TRP C CH2 1 
ATOM 2327 N N   . ASP B 2 217 ? 89.346  123.823 63.853  1.00 69.17  ? 212 ASP C N   1 
ATOM 2328 C CA  . ASP B 2 217 ? 88.989  122.668 63.041  1.00 70.90  ? 212 ASP C CA  1 
ATOM 2329 C C   . ASP B 2 217 ? 90.273  121.998 62.574  1.00 66.72  ? 212 ASP C C   1 
ATOM 2330 O O   . ASP B 2 217 ? 91.121  122.641 61.947  1.00 64.21  ? 212 ASP C O   1 
ATOM 2331 C CB  . ASP B 2 217 ? 88.127  123.086 61.850  1.00 67.96  ? 212 ASP C CB  1 
ATOM 2332 C CG  . ASP B 2 217 ? 87.343  121.932 61.263  1.00 69.16  ? 212 ASP C CG  1 
ATOM 2333 O OD1 . ASP B 2 217 ? 87.495  120.794 61.754  1.00 68.85  ? 212 ASP C OD1 1 
ATOM 2334 O OD2 . ASP B 2 217 ? 86.569  122.164 60.312  1.00 67.29  ? 212 ASP C OD2 1 
ATOM 2335 N N   . VAL B 2 218 ? 90.413  120.709 62.883  1.00 66.65  ? 213 VAL C N   1 
ATOM 2336 C CA  . VAL B 2 218 ? 91.646  119.998 62.562  1.00 68.58  ? 213 VAL C CA  1 
ATOM 2337 C C   . VAL B 2 218 ? 91.815  119.871 61.053  1.00 67.53  ? 213 VAL C C   1 
ATOM 2338 O O   . VAL B 2 218 ? 92.931  119.975 60.529  1.00 68.25  ? 213 VAL C O   1 
ATOM 2339 C CB  . VAL B 2 218 ? 91.656  118.621 63.251  1.00 67.57  ? 213 VAL C CB  1 
ATOM 2340 C CG1 . VAL B 2 218 ? 92.967  117.895 62.987  1.00 64.40  ? 213 VAL C CG1 1 
ATOM 2341 C CG2 . VAL B 2 218 ? 91.422  118.768 64.750  1.00 63.06  ? 213 VAL C CG2 1 
ATOM 2342 N N   . ARG B 2 219 ? 90.721  119.645 60.331  1.00 72.44  ? 214 ARG C N   1 
ATOM 2343 C CA  . ARG B 2 219 ? 90.777  119.368 58.902  1.00 74.64  ? 214 ARG C CA  1 
ATOM 2344 C C   . ARG B 2 219 ? 90.702  120.621 58.037  1.00 72.32  ? 214 ARG C C   1 
ATOM 2345 O O   . ARG B 2 219 ? 90.776  120.506 56.810  1.00 73.28  ? 214 ARG C O   1 
ATOM 2346 C CB  . ARG B 2 219 ? 89.644  118.414 58.511  1.00 75.54  ? 214 ARG C CB  1 
ATOM 2347 C CG  . ARG B 2 219 ? 89.474  117.223 59.446  1.00 74.27  ? 214 ARG C CG  1 
ATOM 2348 C CD  . ARG B 2 219 ? 90.797  116.528 59.737  1.00 73.85  ? 214 ARG C CD  1 
ATOM 2349 N NE  . ARG B 2 219 ? 91.545  116.222 58.524  1.00 75.71  ? 214 ARG C NE  1 
ATOM 2350 C CZ  . ARG B 2 219 ? 92.820  115.858 58.498  1.00 75.00  ? 214 ARG C CZ  1 
ATOM 2351 N NH1 . ARG B 2 219 ? 93.534  115.754 59.608  1.00 74.06  ? 214 ARG C NH1 1 
ATOM 2352 N NH2 . ARG B 2 219 ? 93.396  115.595 57.329  1.00 73.75  ? 214 ARG C NH2 1 
ATOM 2353 N N   . GLU B 2 220 ? 90.554  121.806 58.632  1.00 75.92  ? 215 GLU C N   1 
ATOM 2354 C CA  . GLU B 2 220 ? 90.462  123.047 57.869  1.00 77.81  ? 215 GLU C CA  1 
ATOM 2355 C C   . GLU B 2 220 ? 91.401  124.147 58.340  1.00 78.79  ? 215 GLU C C   1 
ATOM 2356 O O   . GLU B 2 220 ? 91.691  125.053 57.551  1.00 80.85  ? 215 GLU C O   1 
ATOM 2357 C CB  . GLU B 2 220 ? 89.026  123.590 57.897  1.00 79.43  ? 215 GLU C CB  1 
ATOM 2358 C CG  . GLU B 2 220 ? 88.110  122.989 56.837  1.00 79.43  ? 215 GLU C CG  1 
ATOM 2359 C CD  . GLU B 2 220 ? 87.765  121.539 57.106  1.00 80.04  ? 215 GLU C CD  1 
ATOM 2360 O OE1 . GLU B 2 220 ? 87.817  121.121 58.281  1.00 81.60  ? 215 GLU C OE1 1 
ATOM 2361 O OE2 . GLU B 2 220 ? 87.442  120.814 56.142  1.00 80.12  ? 215 GLU C OE2 1 
ATOM 2362 N N   . GLY B 2 221 ? 91.879  124.111 59.579  1.00 72.06  ? 216 GLY C N   1 
ATOM 2363 C CA  . GLY B 2 221 ? 92.825  125.110 60.046  1.00 72.36  ? 216 GLY C CA  1 
ATOM 2364 C C   . GLY B 2 221 ? 92.272  126.514 60.155  1.00 70.94  ? 216 GLY C C   1 
ATOM 2365 O O   . GLY B 2 221 ? 92.987  127.480 59.860  1.00 68.85  ? 216 GLY C O   1 
ATOM 2366 N N   . MET B 2 222 ? 91.018  126.656 60.583  1.00 72.01  ? 217 MET C N   1 
ATOM 2367 C CA  . MET B 2 222 ? 90.383  127.956 60.737  1.00 73.34  ? 217 MET C CA  1 
ATOM 2368 C C   . MET B 2 222 ? 89.671  128.027 62.080  1.00 70.90  ? 217 MET C C   1 
ATOM 2369 O O   . MET B 2 222 ? 89.134  127.031 62.571  1.00 68.37  ? 217 MET C O   1 
ATOM 2370 C CB  . MET B 2 222 ? 89.381  128.229 59.604  1.00 71.67  ? 217 MET C CB  1 
ATOM 2371 C CG  . MET B 2 222 ? 90.009  128.300 58.220  1.00 71.09  ? 217 MET C CG  1 
ATOM 2372 S SD  . MET B 2 222 ? 91.273  129.580 58.074  1.00 73.97  ? 217 MET C SD  1 
ATOM 2373 C CE  . MET B 2 222 ? 90.302  131.063 58.332  1.00 70.02  ? 217 MET C CE  1 
ATOM 2374 N N   . CYS B 2 223 ? 89.669  129.223 62.666  1.00 63.42  ? 218 CYS C N   1 
ATOM 2375 C CA  . CYS B 2 223 ? 88.989  129.465 63.937  1.00 63.45  ? 218 CYS C CA  1 
ATOM 2376 C C   . CYS B 2 223 ? 87.498  129.606 63.666  1.00 67.12  ? 218 CYS C C   1 
ATOM 2377 O O   . CYS B 2 223 ? 87.038  130.631 63.158  1.00 67.08  ? 218 CYS C O   1 
ATOM 2378 C CB  . CYS B 2 223 ? 89.537  130.712 64.618  1.00 63.37  ? 218 CYS C CB  1 
ATOM 2379 S SG  . CYS B 2 223 ? 88.686  131.134 66.152  1.00 63.05  ? 218 CYS C SG  1 
ATOM 2380 N N   . ARG B 2 224 ? 86.736  128.568 64.006  1.00 71.11  ? 219 ARG C N   1 
ATOM 2381 C CA  . ARG B 2 224 ? 85.297  128.602 63.773  1.00 69.81  ? 219 ARG C CA  1 
ATOM 2382 C C   . ARG B 2 224 ? 84.610  129.581 64.719  1.00 68.67  ? 219 ARG C C   1 
ATOM 2383 O O   . ARG B 2 224 ? 83.765  130.377 64.294  1.00 68.44  ? 219 ARG C O   1 
ATOM 2384 C CB  . ARG B 2 224 ? 84.717  127.197 63.925  1.00 69.82  ? 219 ARG C CB  1 
ATOM 2385 C CG  . ARG B 2 224 ? 83.236  127.096 63.623  1.00 70.85  ? 219 ARG C CG  1 
ATOM 2386 C CD  . ARG B 2 224 ? 82.772  125.652 63.622  1.00 71.03  ? 219 ARG C CD  1 
ATOM 2387 N NE  . ARG B 2 224 ? 83.324  124.900 62.501  1.00 70.65  ? 219 ARG C NE  1 
ATOM 2388 C CZ  . ARG B 2 224 ? 83.014  123.643 62.216  1.00 72.12  ? 219 ARG C CZ  1 
ATOM 2389 N NH1 . ARG B 2 224 ? 82.154  122.958 62.951  1.00 72.27  ? 219 ARG C NH1 1 
ATOM 2390 N NH2 . ARG B 2 224 ? 83.581  123.058 61.165  1.00 69.83  ? 219 ARG C NH2 1 
ATOM 2391 N N   . GLN B 2 225 ? 84.963  129.543 66.003  1.00 65.08  ? 220 GLN C N   1 
ATOM 2392 C CA  . GLN B 2 225 ? 84.326  130.385 67.005  1.00 64.95  ? 220 GLN C CA  1 
ATOM 2393 C C   . GLN B 2 225 ? 85.376  130.933 67.961  1.00 61.50  ? 220 GLN C C   1 
ATOM 2394 O O   . GLN B 2 225 ? 86.469  130.382 68.100  1.00 62.06  ? 220 GLN C O   1 
ATOM 2395 C CB  . GLN B 2 225 ? 83.254  129.612 67.785  1.00 67.56  ? 220 GLN C CB  1 
ATOM 2396 C CG  . GLN B 2 225 ? 82.164  129.022 66.905  1.00 69.55  ? 220 GLN C CG  1 
ATOM 2397 C CD  . GLN B 2 225 ? 80.988  128.492 67.697  1.00 69.65  ? 220 GLN C CD  1 
ATOM 2398 O OE1 . GLN B 2 225 ? 80.831  128.793 68.879  1.00 63.87  ? 220 GLN C OE1 1 
ATOM 2399 N NE2 . GLN B 2 225 ? 80.151  127.693 67.045  1.00 69.93  ? 220 GLN C NE2 1 
ATOM 2400 N N   . THR B 2 226 ? 85.029  132.043 68.610  1.00 58.16  ? 221 THR C N   1 
ATOM 2401 C CA  . THR B 2 226 ? 85.857  132.639 69.647  1.00 57.41  ? 221 THR C CA  1 
ATOM 2402 C C   . THR B 2 226 ? 84.971  133.065 70.808  1.00 59.93  ? 221 THR C C   1 
ATOM 2403 O O   . THR B 2 226 ? 83.800  133.404 70.623  1.00 59.94  ? 221 THR C O   1 
ATOM 2404 C CB  . THR B 2 226 ? 86.651  133.846 69.134  1.00 59.73  ? 221 THR C CB  1 
ATOM 2405 O OG1 . THR B 2 226 ? 87.359  134.448 70.224  1.00 61.03  ? 221 THR C OG1 1 
ATOM 2406 C CG2 . THR B 2 226 ? 85.724  134.877 68.499  1.00 59.63  ? 221 THR C CG2 1 
ATOM 2407 N N   . PHE B 2 227 ? 85.546  133.047 72.010  1.00 59.40  ? 222 PHE C N   1 
ATOM 2408 C CA  . PHE B 2 227 ? 84.803  133.301 73.236  1.00 54.80  ? 222 PHE C CA  1 
ATOM 2409 C C   . PHE B 2 227 ? 85.645  134.158 74.167  1.00 54.06  ? 222 PHE C C   1 
ATOM 2410 O O   . PHE B 2 227 ? 86.876  134.084 74.160  1.00 58.00  ? 222 PHE C O   1 
ATOM 2411 C CB  . PHE B 2 227 ? 84.419  131.991 73.935  1.00 51.67  ? 222 PHE C CB  1 
ATOM 2412 C CG  . PHE B 2 227 ? 83.815  130.974 73.017  1.00 53.80  ? 222 PHE C CG  1 
ATOM 2413 C CD1 . PHE B 2 227 ? 84.617  130.082 72.328  1.00 51.35  ? 222 PHE C CD1 1 
ATOM 2414 C CD2 . PHE B 2 227 ? 82.446  130.914 72.835  1.00 59.38  ? 222 PHE C CD2 1 
ATOM 2415 C CE1 . PHE B 2 227 ? 84.064  129.146 71.480  1.00 54.40  ? 222 PHE C CE1 1 
ATOM 2416 C CE2 . PHE B 2 227 ? 81.888  129.978 71.987  1.00 59.12  ? 222 PHE C CE2 1 
ATOM 2417 C CZ  . PHE B 2 227 ? 82.698  129.094 71.309  1.00 56.46  ? 222 PHE C CZ  1 
ATOM 2418 N N   . THR B 2 228 ? 84.965  134.972 74.972  1.00 51.46  ? 223 THR C N   1 
ATOM 2419 C CA  . THR B 2 228 ? 85.617  135.866 75.918  1.00 52.79  ? 223 THR C CA  1 
ATOM 2420 C C   . THR B 2 228 ? 84.788  135.914 77.194  1.00 53.37  ? 223 THR C C   1 
ATOM 2421 O O   . THR B 2 228 ? 83.727  135.291 77.295  1.00 52.07  ? 223 THR C O   1 
ATOM 2422 C CB  . THR B 2 228 ? 85.790  137.273 75.332  1.00 51.61  ? 223 THR C CB  1 
ATOM 2423 O OG1 . THR B 2 228 ? 84.512  137.797 74.954  1.00 49.55  ? 223 THR C OG1 1 
ATOM 2424 C CG2 . THR B 2 228 ? 86.702  137.246 74.117  1.00 52.70  ? 223 THR C CG2 1 
ATOM 2425 N N   . GLY B 2 229 ? 85.280  136.664 78.177  1.00 54.28  ? 224 GLY C N   1 
ATOM 2426 C CA  . GLY B 2 229 ? 84.536  136.890 79.400  1.00 51.77  ? 224 GLY C CA  1 
ATOM 2427 C C   . GLY B 2 229 ? 85.394  136.875 80.647  1.00 55.36  ? 224 GLY C C   1 
ATOM 2428 O O   . GLY B 2 229 ? 85.058  137.525 81.641  1.00 59.07  ? 224 GLY C O   1 
ATOM 2429 N N   . HIS B 2 230 ? 86.508  136.152 80.608  1.00 48.31  ? 225 HIS C N   1 
ATOM 2430 C CA  . HIS B 2 230 ? 87.389  136.062 81.761  1.00 46.10  ? 225 HIS C CA  1 
ATOM 2431 C C   . HIS B 2 230 ? 88.270  137.307 81.845  1.00 50.45  ? 225 HIS C C   1 
ATOM 2432 O O   . HIS B 2 230 ? 88.153  138.241 81.048  1.00 51.67  ? 225 HIS C O   1 
ATOM 2433 C CB  . HIS B 2 230 ? 88.229  134.791 81.684  1.00 50.19  ? 225 HIS C CB  1 
ATOM 2434 C CG  . HIS B 2 230 ? 87.490  133.552 82.077  1.00 50.26  ? 225 HIS C CG  1 
ATOM 2435 N ND1 . HIS B 2 230 ? 87.213  133.237 83.389  1.00 47.67  ? 225 HIS C ND1 1 
ATOM 2436 C CD2 . HIS B 2 230 ? 86.987  132.539 81.333  1.00 48.21  ? 225 HIS C CD2 1 
ATOM 2437 C CE1 . HIS B 2 230 ? 86.563  132.089 83.436  1.00 47.47  ? 225 HIS C CE1 1 
ATOM 2438 N NE2 . HIS B 2 230 ? 86.415  131.644 82.202  1.00 49.45  ? 225 HIS C NE2 1 
ATOM 2439 N N   . GLU B 2 231 ? 89.169  137.321 82.833  1.00 57.01  ? 226 GLU C N   1 
ATOM 2440 C CA  . GLU B 2 231 ? 90.051  138.460 83.050  1.00 57.72  ? 226 GLU C CA  1 
ATOM 2441 C C   . GLU B 2 231 ? 91.501  138.070 83.298  1.00 58.29  ? 226 GLU C C   1 
ATOM 2442 O O   . GLU B 2 231 ? 92.337  138.963 83.463  1.00 56.25  ? 226 GLU C O   1 
ATOM 2443 C CB  . GLU B 2 231 ? 89.549  139.299 84.238  1.00 54.72  ? 226 GLU C CB  1 
ATOM 2444 C CG  . GLU B 2 231 ? 88.137  139.829 84.065  1.00 57.60  ? 226 GLU C CG  1 
ATOM 2445 C CD  . GLU B 2 231 ? 87.995  140.713 82.844  1.00 60.91  ? 226 GLU C CD  1 
ATOM 2446 O OE1 . GLU B 2 231 ? 89.004  141.321 82.429  1.00 57.00  ? 226 GLU C OE1 1 
ATOM 2447 O OE2 . GLU B 2 231 ? 86.877  140.795 82.295  1.00 59.29  ? 226 GLU C OE2 1 
ATOM 2448 N N   . SER B 2 232 ? 91.828  136.782 83.329  1.00 53.98  ? 227 SER C N   1 
ATOM 2449 C CA  . SER B 2 232 ? 93.177  136.327 83.621  1.00 53.88  ? 227 SER C CA  1 
ATOM 2450 C C   . SER B 2 232 ? 93.507  135.156 82.708  1.00 52.76  ? 227 SER C C   1 
ATOM 2451 O O   . SER B 2 232 ? 92.675  134.697 81.921  1.00 52.54  ? 227 SER C O   1 
ATOM 2452 C CB  . SER B 2 232 ? 93.326  135.926 85.094  1.00 55.76  ? 227 SER C CB  1 
ATOM 2453 O OG  . SER B 2 232 ? 94.682  135.972 85.501  1.00 55.99  ? 227 SER C OG  1 
ATOM 2454 N N   . ASP B 2 233 ? 94.746  134.684 82.812  1.00 54.42  ? 228 ASP C N   1 
ATOM 2455 C CA  . ASP B 2 233 ? 95.195  133.546 82.019  1.00 58.05  ? 228 ASP C CA  1 
ATOM 2456 C C   . ASP B 2 233 ? 94.315  132.328 82.273  1.00 57.55  ? 228 ASP C C   1 
ATOM 2457 O O   . ASP B 2 233 ? 93.996  132.006 83.420  1.00 58.09  ? 228 ASP C O   1 
ATOM 2458 C CB  . ASP B 2 233 ? 96.652  133.223 82.353  1.00 56.91  ? 228 ASP C CB  1 
ATOM 2459 C CG  . ASP B 2 233 ? 97.613  134.265 81.826  1.00 58.46  ? 228 ASP C CG  1 
ATOM 2460 O OD1 . ASP B 2 233 ? 97.197  135.073 80.972  1.00 59.18  ? 228 ASP C OD1 1 
ATOM 2461 O OD2 . ASP B 2 233 ? 98.780  134.278 82.266  1.00 57.67  ? 228 ASP C OD2 1 
ATOM 2462 N N   . ILE B 2 234 ? 93.929  131.652 81.195  1.00 39.85  ? 229 ILE C N   1 
ATOM 2463 C CA  . ILE B 2 234 ? 93.135  130.432 81.285  1.00 44.67  ? 229 ILE C CA  1 
ATOM 2464 C C   . ILE B 2 234 ? 94.094  129.257 81.428  1.00 42.97  ? 229 ILE C C   1 
ATOM 2465 O O   . ILE B 2 234 ? 94.883  128.973 80.521  1.00 37.97  ? 229 ILE C O   1 
ATOM 2466 C CB  . ILE B 2 234 ? 92.226  130.266 80.058  1.00 43.85  ? 229 ILE C CB  1 
ATOM 2467 C CG1 . ILE B 2 234 ? 91.382  131.527 79.858  1.00 39.91  ? 229 ILE C CG1 1 
ATOM 2468 C CG2 . ILE B 2 234 ? 91.326  129.041 80.218  1.00 38.14  ? 229 ILE C CG2 1 
ATOM 2469 C CD1 . ILE B 2 234 ? 90.456  131.473 78.669  1.00 38.12  ? 229 ILE C CD1 1 
ATOM 2470 N N   . ASN B 2 235 ? 94.020  128.570 82.568  1.00 40.22  ? 230 ASN C N   1 
ATOM 2471 C CA  . ASN B 2 235 ? 94.983  127.530 82.906  1.00 43.47  ? 230 ASN C CA  1 
ATOM 2472 C C   . ASN B 2 235 ? 94.533  126.136 82.494  1.00 37.76  ? 230 ASN C C   1 
ATOM 2473 O O   . ASN B 2 235 ? 95.379  125.275 82.230  1.00 30.92  ? 230 ASN C O   1 
ATOM 2474 C CB  . ASN B 2 235 ? 95.246  127.541 84.410  1.00 46.23  ? 230 ASN C CB  1 
ATOM 2475 C CG  . ASN B 2 235 ? 95.856  128.833 84.881  1.00 47.01  ? 230 ASN C CG  1 
ATOM 2476 O OD1 . ASN B 2 235 ? 95.300  129.519 85.735  1.00 42.87  ? 230 ASN C OD1 1 
ATOM 2477 N ND2 . ASN B 2 235 ? 97.010  129.175 84.326  1.00 47.28  ? 230 ASN C ND2 1 
ATOM 2478 N N   . ALA B 2 236 ? 93.228  125.890 82.450  1.00 30.58  ? 231 ALA C N   1 
ATOM 2479 C CA  . ALA B 2 236 ? 92.700  124.583 82.104  1.00 26.30  ? 231 ALA C CA  1 
ATOM 2480 C C   . ALA B 2 236 ? 91.442  124.753 81.270  1.00 31.82  ? 231 ALA C C   1 
ATOM 2481 O O   . ALA B 2 236 ? 90.712  125.737 81.408  1.00 20.74  ? 231 ALA C O   1 
ATOM 2482 C CB  . ALA B 2 236 ? 92.391  123.755 83.353  1.00 20.63  ? 231 ALA C CB  1 
ATOM 2483 N N   . ILE B 2 237 ? 91.201  123.781 80.397  1.00 40.24  ? 232 ILE C N   1 
ATOM 2484 C CA  . ILE B 2 237 ? 89.992  123.743 79.585  1.00 32.92  ? 232 ILE C CA  1 
ATOM 2485 C C   . ILE B 2 237 ? 89.658  122.281 79.329  1.00 24.87  ? 232 ILE C C   1 
ATOM 2486 O O   . ILE B 2 237 ? 90.551  121.448 79.158  1.00 19.78  ? 232 ILE C O   1 
ATOM 2487 C CB  . ILE B 2 237 ? 90.170  124.548 78.275  1.00 30.54  ? 232 ILE C CB  1 
ATOM 2488 C CG1 . ILE B 2 237 ? 88.818  124.976 77.704  1.00 34.79  ? 232 ILE C CG1 1 
ATOM 2489 C CG2 . ILE B 2 237 ? 90.930  123.745 77.237  1.00 30.32  ? 232 ILE C CG2 1 
ATOM 2490 C CD1 . ILE B 2 237 ? 88.914  126.132 76.746  1.00 26.64  ? 232 ILE C CD1 1 
ATOM 2491 N N   . CYS B 2 238 ? 88.367  121.969 79.327  1.00 31.57  ? 233 CYS C N   1 
ATOM 2492 C CA  . CYS B 2 238 ? 87.905  120.603 79.136  1.00 31.94  ? 233 CYS C CA  1 
ATOM 2493 C C   . CYS B 2 238 ? 86.642  120.637 78.292  1.00 32.73  ? 233 CYS C C   1 
ATOM 2494 O O   . CYS B 2 238 ? 86.062  121.697 78.046  1.00 35.27  ? 233 CYS C O   1 
ATOM 2495 C CB  . CYS B 2 238 ? 87.646  119.903 80.474  1.00 36.05  ? 233 CYS C CB  1 
ATOM 2496 S SG  . CYS B 2 238 ? 87.164  118.165 80.310  1.00 41.05  ? 233 CYS C SG  1 
ATOM 2497 N N   . PHE B 2 239 ? 86.222  119.461 77.844  1.00 36.38  ? 234 PHE C N   1 
ATOM 2498 C CA  . PHE B 2 239 ? 85.080  119.322 76.958  1.00 38.94  ? 234 PHE C CA  1 
ATOM 2499 C C   . PHE B 2 239 ? 83.949  118.591 77.662  1.00 44.80  ? 234 PHE C C   1 
ATOM 2500 O O   . PHE B 2 239 ? 84.174  117.592 78.351  1.00 49.12  ? 234 PHE C O   1 
ATOM 2501 C CB  . PHE B 2 239 ? 85.463  118.571 75.681  1.00 39.81  ? 234 PHE C CB  1 
ATOM 2502 C CG  . PHE B 2 239 ? 85.496  119.437 74.459  1.00 37.72  ? 234 PHE C CG  1 
ATOM 2503 C CD1 . PHE B 2 239 ? 86.607  120.199 74.157  1.00 37.34  ? 234 PHE C CD1 1 
ATOM 2504 C CD2 . PHE B 2 239 ? 84.408  119.485 73.608  1.00 41.39  ? 234 PHE C CD2 1 
ATOM 2505 C CE1 . PHE B 2 239 ? 86.632  120.993 73.031  1.00 39.87  ? 234 PHE C CE1 1 
ATOM 2506 C CE2 . PHE B 2 239 ? 84.428  120.278 72.482  1.00 45.26  ? 234 PHE C CE2 1 
ATOM 2507 C CZ  . PHE B 2 239 ? 85.541  121.031 72.194  1.00 42.23  ? 234 PHE C CZ  1 
ATOM 2508 N N   . PHE B 2 240 ? 82.733  119.098 77.480  1.00 49.70  ? 235 PHE C N   1 
ATOM 2509 C CA  . PHE B 2 240 ? 81.559  118.431 78.005  1.00 50.76  ? 235 PHE C CA  1 
ATOM 2510 C C   . PHE B 2 240 ? 81.375  117.081 77.309  1.00 57.26  ? 235 PHE C C   1 
ATOM 2511 O O   . PHE B 2 240 ? 81.712  116.933 76.132  1.00 55.81  ? 235 PHE C O   1 
ATOM 2512 C CB  . PHE B 2 240 ? 80.325  119.300 77.794  1.00 48.53  ? 235 PHE C CB  1 
ATOM 2513 C CG  . PHE B 2 240 ? 79.205  118.999 78.738  1.00 54.10  ? 235 PHE C CG  1 
ATOM 2514 C CD1 . PHE B 2 240 ? 79.212  119.514 80.019  1.00 51.90  ? 235 PHE C CD1 1 
ATOM 2515 C CD2 . PHE B 2 240 ? 78.139  118.209 78.344  1.00 55.67  ? 235 PHE C CD2 1 
ATOM 2516 C CE1 . PHE B 2 240 ? 78.184  119.244 80.890  1.00 51.31  ? 235 PHE C CE1 1 
ATOM 2517 C CE2 . PHE B 2 240 ? 77.110  117.935 79.215  1.00 54.75  ? 235 PHE C CE2 1 
ATOM 2518 C CZ  . PHE B 2 240 ? 77.133  118.455 80.486  1.00 55.40  ? 235 PHE C CZ  1 
ATOM 2519 N N   . PRO B 2 241 ? 80.834  116.070 78.014  1.00 57.15  ? 236 PRO C N   1 
ATOM 2520 C CA  . PRO B 2 241 ? 80.720  114.736 77.408  1.00 55.93  ? 236 PRO C CA  1 
ATOM 2521 C C   . PRO B 2 241 ? 79.944  114.669 76.098  1.00 58.40  ? 236 PRO C C   1 
ATOM 2522 O O   . PRO B 2 241 ? 79.909  113.606 75.472  1.00 59.79  ? 236 PRO C O   1 
ATOM 2523 C CB  . PRO B 2 241 ? 80.011  113.930 78.502  1.00 55.18  ? 236 PRO C CB  1 
ATOM 2524 C CG  . PRO B 2 241 ? 80.463  114.553 79.749  1.00 51.76  ? 236 PRO C CG  1 
ATOM 2525 C CD  . PRO B 2 241 ? 80.564  116.019 79.464  1.00 52.03  ? 236 PRO C CD  1 
ATOM 2526 N N   . ASN B 2 242 ? 79.318  115.767 75.667  1.00 63.66  ? 237 ASN C N   1 
ATOM 2527 C CA  . ASN B 2 242 ? 78.571  115.782 74.417  1.00 62.29  ? 237 ASN C CA  1 
ATOM 2528 C C   . ASN B 2 242 ? 79.244  116.588 73.316  1.00 64.39  ? 237 ASN C C   1 
ATOM 2529 O O   . ASN B 2 242 ? 78.863  116.445 72.150  1.00 66.78  ? 237 ASN C O   1 
ATOM 2530 C CB  . ASN B 2 242 ? 77.157  116.332 74.649  1.00 65.09  ? 237 ASN C CB  1 
ATOM 2531 C CG  . ASN B 2 242 ? 77.148  117.811 74.964  1.00 67.61  ? 237 ASN C CG  1 
ATOM 2532 O OD1 . ASN B 2 242 ? 78.173  118.388 75.327  1.00 67.40  ? 237 ASN C OD1 1 
ATOM 2533 N ND2 . ASN B 2 242 ? 75.985  118.435 74.829  1.00 67.50  ? 237 ASN C ND2 1 
ATOM 2534 N N   . GLY B 2 243 ? 80.227  117.422 73.647  1.00 66.10  ? 238 GLY C N   1 
ATOM 2535 C CA  . GLY B 2 243 ? 80.937  118.191 72.646  1.00 66.59  ? 238 GLY C CA  1 
ATOM 2536 C C   . GLY B 2 243 ? 80.282  119.492 72.241  1.00 61.47  ? 238 GLY C C   1 
ATOM 2537 O O   . GLY B 2 243 ? 80.757  120.136 71.300  1.00 60.84  ? 238 GLY C O   1 
ATOM 2538 N N   . ASN B 2 244 ? 79.209  119.901 72.914  1.00 62.60  ? 239 ASN C N   1 
ATOM 2539 C CA  . ASN B 2 244 ? 78.527  121.153 72.616  1.00 66.20  ? 239 ASN C CA  1 
ATOM 2540 C C   . ASN B 2 244 ? 78.896  122.268 73.585  1.00 64.89  ? 239 ASN C C   1 
ATOM 2541 O O   . ASN B 2 244 ? 78.268  123.331 73.555  1.00 65.11  ? 239 ASN C O   1 
ATOM 2542 C CB  . ASN B 2 244 ? 77.012  120.941 72.625  1.00 64.53  ? 239 ASN C CB  1 
ATOM 2543 C CG  . ASN B 2 244 ? 76.546  120.008 71.526  1.00 66.92  ? 239 ASN C CG  1 
ATOM 2544 O OD1 . ASN B 2 244 ? 77.079  120.020 70.416  1.00 68.81  ? 239 ASN C OD1 1 
ATOM 2545 N ND2 . ASN B 2 244 ? 75.543  119.192 71.829  1.00 65.78  ? 239 ASN C ND2 1 
ATOM 2546 N N   . ALA B 2 245 ? 79.891  122.057 74.440  1.00 57.65  ? 240 ALA C N   1 
ATOM 2547 C CA  . ALA B 2 245 ? 80.260  123.046 75.444  1.00 56.60  ? 240 ALA C CA  1 
ATOM 2548 C C   . ALA B 2 245 ? 81.683  122.761 75.911  1.00 57.84  ? 240 ALA C C   1 
ATOM 2549 O O   . ALA B 2 245 ? 82.329  121.811 75.463  1.00 55.06  ? 240 ALA C O   1 
ATOM 2550 C CB  . ALA B 2 245 ? 79.271  123.033 76.613  1.00 51.17  ? 240 ALA C CB  1 
ATOM 2551 N N   . PHE B 2 246 ? 82.173  123.610 76.810  1.00 44.40  ? 241 PHE C N   1 
ATOM 2552 C CA  . PHE B 2 246 ? 83.484  123.425 77.412  1.00 36.93  ? 241 PHE C CA  1 
ATOM 2553 C C   . PHE B 2 246 ? 83.564  124.302 78.652  1.00 37.08  ? 241 PHE C C   1 
ATOM 2554 O O   . PHE B 2 246 ? 82.786  125.244 78.816  1.00 40.19  ? 241 PHE C O   1 
ATOM 2555 C CB  . PHE B 2 246 ? 84.609  123.756 76.427  1.00 35.28  ? 241 PHE C CB  1 
ATOM 2556 C CG  . PHE B 2 246 ? 84.482  125.105 75.792  1.00 42.70  ? 241 PHE C CG  1 
ATOM 2557 C CD1 . PHE B 2 246 ? 83.705  125.285 74.662  1.00 41.40  ? 241 PHE C CD1 1 
ATOM 2558 C CD2 . PHE B 2 246 ? 85.148  126.197 76.319  1.00 43.22  ? 241 PHE C CD2 1 
ATOM 2559 C CE1 . PHE B 2 246 ? 83.591  126.524 74.080  1.00 39.69  ? 241 PHE C CE1 1 
ATOM 2560 C CE2 . PHE B 2 246 ? 85.036  127.437 75.738  1.00 35.77  ? 241 PHE C CE2 1 
ATOM 2561 C CZ  . PHE B 2 246 ? 84.257  127.599 74.620  1.00 39.41  ? 241 PHE C CZ  1 
ATOM 2562 N N   . ALA B 2 247 ? 84.514  123.976 79.526  1.00 34.89  ? 242 ALA C N   1 
ATOM 2563 C CA  . ALA B 2 247 ? 84.703  124.679 80.787  1.00 32.25  ? 242 ALA C CA  1 
ATOM 2564 C C   . ALA B 2 247 ? 86.057  125.368 80.778  1.00 33.58  ? 242 ALA C C   1 
ATOM 2565 O O   . ALA B 2 247 ? 87.068  124.746 80.445  1.00 27.92  ? 242 ALA C O   1 
ATOM 2566 C CB  . ALA B 2 247 ? 84.608  123.723 81.975  1.00 31.47  ? 242 ALA C CB  1 
ATOM 2567 N N   . THR B 2 248 ? 86.071  126.644 81.153  1.00 41.66  ? 243 THR C N   1 
ATOM 2568 C CA  . THR B 2 248 ? 87.271  127.478 81.123  1.00 42.27  ? 243 THR C CA  1 
ATOM 2569 C C   . THR B 2 248 ? 87.614  127.878 82.553  1.00 40.36  ? 243 THR C C   1 
ATOM 2570 O O   . THR B 2 248 ? 86.974  128.765 83.123  1.00 36.45  ? 243 THR C O   1 
ATOM 2571 C CB  . THR B 2 248 ? 87.057  128.713 80.253  1.00 44.85  ? 243 THR C CB  1 
ATOM 2572 O OG1 . THR B 2 248 ? 86.044  129.534 80.843  1.00 49.06  ? 243 THR C OG1 1 
ATOM 2573 C CG2 . THR B 2 248 ? 86.630  128.320 78.848  1.00 45.98  ? 243 THR C CG2 1 
ATOM 2574 N N   . GLY B 2 249 ? 88.630  127.234 83.122  1.00 36.37  ? 244 GLY C N   1 
ATOM 2575 C CA  . GLY B 2 249 ? 89.081  127.558 84.460  1.00 33.70  ? 244 GLY C CA  1 
ATOM 2576 C C   . GLY B 2 249 ? 90.223  128.549 84.449  1.00 31.41  ? 244 GLY C C   1 
ATOM 2577 O O   . GLY B 2 249 ? 91.308  128.242 83.949  1.00 32.92  ? 244 GLY C O   1 
ATOM 2578 N N   . SER B 2 250 ? 90.000  129.733 85.009  1.00 41.09  ? 245 SER C N   1 
ATOM 2579 C CA  . SER B 2 250 ? 90.950  130.831 84.918  1.00 45.24  ? 245 SER C CA  1 
ATOM 2580 C C   . SER B 2 250 ? 91.805  130.934 86.177  1.00 47.10  ? 245 SER C C   1 
ATOM 2581 O O   . SER B 2 250 ? 91.572  130.266 87.186  1.00 42.29  ? 245 SER C O   1 
ATOM 2582 C CB  . SER B 2 250 ? 90.219  132.152 84.672  1.00 39.62  ? 245 SER C CB  1 
ATOM 2583 O OG  . SER B 2 250 ? 89.742  132.211 83.345  1.00 45.41  ? 245 SER C OG  1 
ATOM 2584 N N   . ASP B 2 251 ? 92.804  131.808 86.099  1.00 54.29  ? 246 ASP C N   1 
ATOM 2585 C CA  . ASP B 2 251 ? 93.758  132.031 87.173  1.00 57.24  ? 246 ASP C CA  1 
ATOM 2586 C C   . ASP B 2 251 ? 93.275  133.075 88.175  1.00 60.34  ? 246 ASP C C   1 
ATOM 2587 O O   . ASP B 2 251 ? 94.042  133.473 89.059  1.00 58.27  ? 246 ASP C O   1 
ATOM 2588 C CB  . ASP B 2 251 ? 95.108  132.454 86.585  1.00 53.93  ? 246 ASP C CB  1 
ATOM 2589 C CG  . ASP B 2 251 ? 96.274  132.126 87.496  1.00 55.21  ? 246 ASP C CG  1 
ATOM 2590 O OD1 . ASP B 2 251 ? 96.063  131.456 88.528  1.00 54.41  ? 246 ASP C OD1 1 
ATOM 2591 O OD2 . ASP B 2 251 ? 97.408  132.540 87.176  1.00 56.70  ? 246 ASP C OD2 1 
ATOM 2592 N N   . ASP B 2 252 ? 92.030  133.535 88.047  1.00 61.33  ? 247 ASP C N   1 
ATOM 2593 C CA  . ASP B 2 252 ? 91.422  134.469 88.985  1.00 56.33  ? 247 ASP C CA  1 
ATOM 2594 C C   . ASP B 2 252 ? 90.256  133.831 89.738  1.00 56.56  ? 247 ASP C C   1 
ATOM 2595 O O   . ASP B 2 252 ? 89.294  134.512 90.099  1.00 58.12  ? 247 ASP C O   1 
ATOM 2596 C CB  . ASP B 2 252 ? 90.962  135.729 88.255  1.00 58.43  ? 247 ASP C CB  1 
ATOM 2597 C CG  . ASP B 2 252 ? 90.023  135.427 87.102  1.00 58.91  ? 247 ASP C CG  1 
ATOM 2598 O OD1 . ASP B 2 252 ? 89.814  134.236 86.795  1.00 58.40  ? 247 ASP C OD1 1 
ATOM 2599 O OD2 . ASP B 2 252 ? 89.489  136.384 86.503  1.00 62.26  ? 247 ASP C OD2 1 
ATOM 2600 N N   . ALA B 2 253 ? 90.331  132.521 89.977  1.00 55.32  ? 248 ALA C N   1 
ATOM 2601 C CA  . ALA B 2 253 ? 89.318  131.793 90.739  1.00 56.36  ? 248 ALA C CA  1 
ATOM 2602 C C   . ALA B 2 253 ? 87.934  131.953 90.114  1.00 61.50  ? 248 ALA C C   1 
ATOM 2603 O O   . ALA B 2 253 ? 86.990  132.433 90.743  1.00 64.52  ? 248 ALA C O   1 
ATOM 2604 C CB  . ALA B 2 253 ? 89.300  132.247 92.200  1.00 55.76  ? 248 ALA C CB  1 
ATOM 2605 N N   . THR B 2 254 ? 87.825  131.539 88.856  1.00 52.57  ? 249 THR C N   1 
ATOM 2606 C CA  . THR B 2 254 ? 86.538  131.529 88.183  1.00 46.89  ? 249 THR C CA  1 
ATOM 2607 C C   . THR B 2 254 ? 86.517  130.406 87.159  1.00 48.12  ? 249 THR C C   1 
ATOM 2608 O O   . THR B 2 254 ? 87.555  129.999 86.633  1.00 41.43  ? 249 THR C O   1 
ATOM 2609 C CB  . THR B 2 254 ? 86.237  132.871 87.501  1.00 44.50  ? 249 THR C CB  1 
ATOM 2610 O OG1 . THR B 2 254 ? 87.379  133.296 86.746  1.00 44.70  ? 249 THR C OG1 1 
ATOM 2611 C CG2 . THR B 2 254 ? 85.893  133.930 88.530  1.00 45.51  ? 249 THR C CG2 1 
ATOM 2612 N N   . CYS B 2 255 ? 85.320  129.896 86.906  1.00 50.76  ? 250 CYS C N   1 
ATOM 2613 C CA  . CYS B 2 255 ? 85.060  128.980 85.811  1.00 46.05  ? 250 CYS C CA  1 
ATOM 2614 C C   . CYS B 2 255 ? 83.778  129.425 85.128  1.00 46.97  ? 250 CYS C C   1 
ATOM 2615 O O   . CYS B 2 255 ? 82.921  130.062 85.743  1.00 46.43  ? 250 CYS C O   1 
ATOM 2616 C CB  . CYS B 2 255 ? 84.930  127.524 86.290  1.00 43.07  ? 250 CYS C CB  1 
ATOM 2617 S SG  . CYS B 2 255 ? 86.448  126.783 86.913  1.00 50.98  ? 250 CYS C SG  1 
ATOM 2618 N N   . ARG B 2 256 ? 83.662  129.111 83.843  1.00 44.82  ? 251 ARG C N   1 
ATOM 2619 C CA  . ARG B 2 256 ? 82.475  129.457 83.080  1.00 44.82  ? 251 ARG C CA  1 
ATOM 2620 C C   . ARG B 2 256 ? 82.178  128.342 82.092  1.00 45.48  ? 251 ARG C C   1 
ATOM 2621 O O   . ARG B 2 256 ? 83.086  127.671 81.597  1.00 45.76  ? 251 ARG C O   1 
ATOM 2622 C CB  . ARG B 2 256 ? 82.647  130.789 82.339  1.00 50.57  ? 251 ARG C CB  1 
ATOM 2623 C CG  . ARG B 2 256 ? 82.814  131.995 83.248  1.00 46.67  ? 251 ARG C CG  1 
ATOM 2624 C CD  . ARG B 2 256 ? 83.369  133.187 82.491  1.00 45.86  ? 251 ARG C CD  1 
ATOM 2625 N NE  . ARG B 2 256 ? 83.874  134.222 83.388  1.00 44.55  ? 251 ARG C NE  1 
ATOM 2626 C CZ  . ARG B 2 256 ? 83.184  135.278 83.797  1.00 46.48  ? 251 ARG C CZ  1 
ATOM 2627 N NH1 . ARG B 2 256 ? 81.931  135.477 83.423  1.00 49.49  ? 251 ARG C NH1 1 
ATOM 2628 N NH2 . ARG B 2 256 ? 83.769  136.161 84.602  1.00 46.27  ? 251 ARG C NH2 1 
ATOM 2629 N N   . LEU B 2 257 ? 80.894  128.157 81.811  1.00 49.66  ? 252 LEU C N   1 
ATOM 2630 C CA  . LEU B 2 257 ? 80.420  127.148 80.873  1.00 51.74  ? 252 LEU C CA  1 
ATOM 2631 C C   . LEU B 2 257 ? 80.003  127.858 79.591  1.00 56.01  ? 252 LEU C C   1 
ATOM 2632 O O   . LEU B 2 257 ? 78.962  128.522 79.555  1.00 49.12  ? 252 LEU C O   1 
ATOM 2633 C CB  . LEU B 2 257 ? 79.258  126.357 81.469  1.00 46.03  ? 252 LEU C CB  1 
ATOM 2634 C CG  . LEU B 2 257 ? 78.963  125.012 80.812  1.00 48.20  ? 252 LEU C CG  1 
ATOM 2635 C CD1 . LEU B 2 257 ? 79.978  123.974 81.255  1.00 49.02  ? 252 LEU C CD1 1 
ATOM 2636 C CD2 . LEU B 2 257 ? 77.553  124.556 81.132  1.00 52.36  ? 252 LEU C CD2 1 
ATOM 2637 N N   . PHE B 2 258 ? 80.817  127.722 78.549  1.00 53.81  ? 253 PHE C N   1 
ATOM 2638 C CA  . PHE B 2 258 ? 80.526  128.292 77.244  1.00 49.71  ? 253 PHE C CA  1 
ATOM 2639 C C   . PHE B 2 258 ? 79.866  127.252 76.349  1.00 52.32  ? 253 PHE C C   1 
ATOM 2640 O O   . PHE B 2 258 ? 79.888  126.052 76.629  1.00 47.79  ? 253 PHE C O   1 
ATOM 2641 C CB  . PHE B 2 258 ? 81.801  128.819 76.586  1.00 52.29  ? 253 PHE C CB  1 
ATOM 2642 C CG  . PHE B 2 258 ? 82.297  130.105 77.175  1.00 55.05  ? 253 PHE C CG  1 
ATOM 2643 C CD1 . PHE B 2 258 ? 81.790  131.321 76.745  1.00 49.92  ? 253 PHE C CD1 1 
ATOM 2644 C CD2 . PHE B 2 258 ? 83.274  130.101 78.155  1.00 53.92  ? 253 PHE C CD2 1 
ATOM 2645 C CE1 . PHE B 2 258 ? 82.247  132.506 77.284  1.00 52.16  ? 253 PHE C CE1 1 
ATOM 2646 C CE2 . PHE B 2 258 ? 83.735  131.287 78.698  1.00 52.47  ? 253 PHE C CE2 1 
ATOM 2647 C CZ  . PHE B 2 258 ? 83.218  132.488 78.262  1.00 52.50  ? 253 PHE C CZ  1 
ATOM 2648 N N   . ASP B 2 259 ? 79.269  127.732 75.262  1.00 72.87  ? 254 ASP C N   1 
ATOM 2649 C CA  . ASP B 2 259 ? 78.534  126.886 74.336  1.00 74.74  ? 254 ASP C CA  1 
ATOM 2650 C C   . ASP B 2 259 ? 78.937  127.220 72.908  1.00 71.90  ? 254 ASP C C   1 
ATOM 2651 O O   . ASP B 2 259 ? 79.365  128.339 72.612  1.00 75.07  ? 254 ASP C O   1 
ATOM 2652 C CB  . ASP B 2 259 ? 77.019  127.056 74.505  1.00 73.03  ? 254 ASP C CB  1 
ATOM 2653 C CG  . ASP B 2 259 ? 76.241  125.869 73.978  1.00 75.03  ? 254 ASP C CG  1 
ATOM 2654 O OD1 . ASP B 2 259 ? 76.584  125.368 72.887  1.00 75.36  ? 254 ASP C OD1 1 
ATOM 2655 O OD2 . ASP B 2 259 ? 75.293  125.430 74.661  1.00 72.36  ? 254 ASP C OD2 1 
ATOM 2656 N N   . LEU B 2 260 ? 78.801  126.232 72.024  1.00 67.98  ? 255 LEU C N   1 
ATOM 2657 C CA  . LEU B 2 260 ? 79.193  126.378 70.629  1.00 70.43  ? 255 LEU C CA  1 
ATOM 2658 C C   . LEU B 2 260 ? 78.042  126.775 69.715  1.00 72.72  ? 255 LEU C C   1 
ATOM 2659 O O   . LEU B 2 260 ? 78.276  127.018 68.527  1.00 68.07  ? 255 LEU C O   1 
ATOM 2660 C CB  . LEU B 2 260 ? 79.809  125.071 70.119  1.00 71.55  ? 255 LEU C CB  1 
ATOM 2661 C CG  . LEU B 2 260 ? 80.984  124.520 70.927  1.00 68.68  ? 255 LEU C CG  1 
ATOM 2662 C CD1 . LEU B 2 260 ? 81.502  123.252 70.275  1.00 68.65  ? 255 LEU C CD1 1 
ATOM 2663 C CD2 . LEU B 2 260 ? 82.090  125.552 71.069  1.00 66.85  ? 255 LEU C CD2 1 
ATOM 2664 N N   . ARG B 2 261 ? 76.816  126.845 70.231  1.00 84.98  ? 256 ARG C N   1 
ATOM 2665 C CA  . ARG B 2 261 ? 75.652  127.254 69.454  1.00 83.77  ? 256 ARG C CA  1 
ATOM 2666 C C   . ARG B 2 261 ? 75.087  128.586 69.920  1.00 84.44  ? 256 ARG C C   1 
ATOM 2667 O O   . ARG B 2 261 ? 74.861  129.482 69.101  1.00 85.02  ? 256 ARG C O   1 
ATOM 2668 C CB  . ARG B 2 261 ? 74.570  126.168 69.522  1.00 83.69  ? 256 ARG C CB  1 
ATOM 2669 C CG  . ARG B 2 261 ? 74.945  124.899 68.770  1.00 85.78  ? 256 ARG C CG  1 
ATOM 2670 C CD  . ARG B 2 261 ? 73.872  123.829 68.871  1.00 85.10  ? 256 ARG C CD  1 
ATOM 2671 N NE  . ARG B 2 261 ? 73.725  123.316 70.227  1.00 83.73  ? 256 ARG C NE  1 
ATOM 2672 C CZ  . ARG B 2 261 ? 72.997  122.257 70.552  1.00 84.54  ? 256 ARG C CZ  1 
ATOM 2673 N NH1 . ARG B 2 261 ? 72.342  121.559 69.638  1.00 84.07  ? 256 ARG C NH1 1 
ATOM 2674 N NH2 . ARG B 2 261 ? 72.925  121.886 71.827  1.00 85.78  ? 256 ARG C NH2 1 
ATOM 2675 N N   . ALA B 2 262 ? 74.853  128.745 71.223  1.00 87.44  ? 257 ALA C N   1 
ATOM 2676 C CA  . ALA B 2 262 ? 74.501  130.056 71.753  1.00 87.97  ? 257 ALA C CA  1 
ATOM 2677 C C   . ALA B 2 262 ? 75.697  130.997 71.767  1.00 87.55  ? 257 ALA C C   1 
ATOM 2678 O O   . ALA B 2 262 ? 75.509  132.218 71.775  1.00 88.04  ? 257 ALA C O   1 
ATOM 2679 C CB  . ALA B 2 262 ? 73.928  129.919 73.164  1.00 86.90  ? 257 ALA C CB  1 
ATOM 2680 N N   . ASP B 2 263 ? 76.915  130.456 71.764  1.00 81.27  ? 258 ASP C N   1 
ATOM 2681 C CA  . ASP B 2 263 ? 78.134  131.257 71.671  1.00 81.36  ? 258 ASP C CA  1 
ATOM 2682 C C   . ASP B 2 263 ? 78.241  132.256 72.820  1.00 83.25  ? 258 ASP C C   1 
ATOM 2683 O O   . ASP B 2 263 ? 78.623  133.411 72.627  1.00 83.09  ? 258 ASP C O   1 
ATOM 2684 C CB  . ASP B 2 263 ? 78.207  131.978 70.324  1.00 81.74  ? 258 ASP C CB  1 
ATOM 2685 C CG  . ASP B 2 263 ? 78.130  131.025 69.150  1.00 83.02  ? 258 ASP C CG  1 
ATOM 2686 O OD1 . ASP B 2 263 ? 77.964  129.808 69.381  1.00 83.95  ? 258 ASP C OD1 1 
ATOM 2687 O OD2 . ASP B 2 263 ? 78.234  131.493 67.996  1.00 82.83  ? 258 ASP C OD2 1 
ATOM 2688 N N   . GLN B 2 264 ? 77.902  131.815 74.029  1.00 72.05  ? 259 GLN C N   1 
ATOM 2689 C CA  . GLN B 2 264 ? 78.032  132.678 75.195  1.00 70.02  ? 259 GLN C CA  1 
ATOM 2690 C C   . GLN B 2 264 ? 78.116  131.820 76.447  1.00 66.25  ? 259 GLN C C   1 
ATOM 2691 O O   . GLN B 2 264 ? 77.675  130.668 76.467  1.00 68.52  ? 259 GLN C O   1 
ATOM 2692 C CB  . GLN B 2 264 ? 76.861  133.664 75.292  1.00 70.36  ? 259 GLN C CB  1 
ATOM 2693 C CG  . GLN B 2 264 ? 77.079  134.793 76.287  1.00 69.00  ? 259 GLN C CG  1 
ATOM 2694 C CD  . GLN B 2 264 ? 78.305  135.618 75.963  1.00 70.15  ? 259 GLN C CD  1 
ATOM 2695 O OE1 . GLN B 2 264 ? 78.673  135.769 74.800  1.00 69.71  ? 259 GLN C OE1 1 
ATOM 2696 N NE2 . GLN B 2 264 ? 78.953  136.149 76.993  1.00 68.96  ? 259 GLN C NE2 1 
ATOM 2697 N N   . GLU B 2 265 ? 78.694  132.405 77.494  1.00 64.69  ? 260 GLU C N   1 
ATOM 2698 C CA  . GLU B 2 265 ? 78.778  131.731 78.782  1.00 68.51  ? 260 GLU C CA  1 
ATOM 2699 C C   . GLU B 2 265 ? 77.386  131.496 79.350  1.00 69.66  ? 260 GLU C C   1 
ATOM 2700 O O   . GLU B 2 265 ? 76.483  132.322 79.189  1.00 65.55  ? 260 GLU C O   1 
ATOM 2701 C CB  . GLU B 2 265 ? 79.609  132.560 79.762  1.00 63.79  ? 260 GLU C CB  1 
ATOM 2702 C CG  . GLU B 2 265 ? 79.170  134.013 79.874  1.00 66.95  ? 260 GLU C CG  1 
ATOM 2703 C CD  . GLU B 2 265 ? 79.841  134.749 81.015  1.00 68.43  ? 260 GLU C CD  1 
ATOM 2704 O OE1 . GLU B 2 265 ? 80.336  134.081 81.946  1.00 69.62  ? 260 GLU C OE1 1 
ATOM 2705 O OE2 . GLU B 2 265 ? 79.873  135.997 80.982  1.00 67.17  ? 260 GLU C OE2 1 
ATOM 2706 N N   . LEU B 2 266 ? 77.214  130.357 80.023  1.00 68.58  ? 261 LEU C N   1 
ATOM 2707 C CA  . LEU B 2 266 ? 75.945  130.014 80.645  1.00 67.83  ? 261 LEU C CA  1 
ATOM 2708 C C   . LEU B 2 266 ? 75.981  130.030 82.165  1.00 68.00  ? 261 LEU C C   1 
ATOM 2709 O O   . LEU B 2 266 ? 74.919  130.128 82.785  1.00 68.30  ? 261 LEU C O   1 
ATOM 2710 C CB  . LEU B 2 266 ? 75.484  128.623 80.185  1.00 68.34  ? 261 LEU C CB  1 
ATOM 2711 C CG  . LEU B 2 266 ? 75.366  128.403 78.677  1.00 68.84  ? 261 LEU C CG  1 
ATOM 2712 C CD1 . LEU B 2 266 ? 74.685  127.072 78.395  1.00 69.67  ? 261 LEU C CD1 1 
ATOM 2713 C CD2 . LEU B 2 266 ? 74.619  129.551 78.013  1.00 68.84  ? 261 LEU C CD2 1 
ATOM 2714 N N   . MET B 2 267 ? 77.158  129.934 82.780  1.00 64.87  ? 262 MET C N   1 
ATOM 2715 C CA  . MET B 2 267 ? 77.237  129.877 84.231  1.00 64.14  ? 262 MET C CA  1 
ATOM 2716 C C   . MET B 2 267 ? 78.599  130.377 84.687  1.00 62.30  ? 262 MET C C   1 
ATOM 2717 O O   . MET B 2 267 ? 79.538  130.507 83.899  1.00 61.95  ? 262 MET C O   1 
ATOM 2718 C CB  . MET B 2 267 ? 76.986  128.455 84.747  1.00 63.83  ? 262 MET C CB  1 
ATOM 2719 C CG  . MET B 2 267 ? 76.391  128.404 86.146  1.00 66.97  ? 262 MET C CG  1 
ATOM 2720 S SD  . MET B 2 267 ? 74.748  129.149 86.226  1.00 71.87  ? 262 MET C SD  1 
ATOM 2721 C CE  . MET B 2 267 ? 74.644  129.573 87.963  1.00 66.91  ? 262 MET C CE  1 
ATOM 2722 N N   . THR B 2 268 ? 78.682  130.671 85.981  1.00 58.19  ? 263 THR C N   1 
ATOM 2723 C CA  . THR B 2 268 ? 79.918  131.053 86.642  1.00 55.26  ? 263 THR C CA  1 
ATOM 2724 C C   . THR B 2 268 ? 80.096  130.177 87.873  1.00 50.43  ? 263 THR C C   1 
ATOM 2725 O O   . THR B 2 268 ? 79.128  129.628 88.403  1.00 52.94  ? 263 THR C O   1 
ATOM 2726 C CB  . THR B 2 268 ? 79.913  132.534 87.051  1.00 56.55  ? 263 THR C CB  1 
ATOM 2727 O OG1 . THR B 2 268 ? 78.861  132.769 87.994  1.00 58.92  ? 263 THR C OG1 1 
ATOM 2728 C CG2 . THR B 2 268 ? 79.709  133.431 85.838  1.00 53.17  ? 263 THR C CG2 1 
ATOM 2729 N N   . TYR B 2 269 ? 81.345  130.028 88.311  1.00 48.46  ? 264 TYR C N   1 
ATOM 2730 C CA  . TYR B 2 269 ? 81.669  129.218 89.489  1.00 52.47  ? 264 TYR C CA  1 
ATOM 2731 C C   . TYR B 2 269 ? 82.734  129.974 90.282  1.00 53.22  ? 264 TYR C C   1 
ATOM 2732 O O   . TYR B 2 269 ? 83.933  129.837 90.023  1.00 54.55  ? 264 TYR C O   1 
ATOM 2733 C CB  . TYR B 2 269 ? 82.139  127.820 89.099  1.00 53.28  ? 264 TYR C CB  1 
ATOM 2734 C CG  . TYR B 2 269 ? 81.213  127.098 88.145  1.00 54.15  ? 264 TYR C CG  1 
ATOM 2735 C CD1 . TYR B 2 269 ? 79.982  126.628 88.569  1.00 55.61  ? 264 TYR C CD1 1 
ATOM 2736 C CD2 . TYR B 2 269 ? 81.574  126.882 86.821  1.00 52.31  ? 264 TYR C CD2 1 
ATOM 2737 C CE1 . TYR B 2 269 ? 79.134  125.969 87.700  1.00 53.28  ? 264 TYR C CE1 1 
ATOM 2738 C CE2 . TYR B 2 269 ? 80.734  126.226 85.946  1.00 52.84  ? 264 TYR C CE2 1 
ATOM 2739 C CZ  . TYR B 2 269 ? 79.516  125.771 86.391  1.00 52.93  ? 264 TYR C CZ  1 
ATOM 2740 O OH  . TYR B 2 269 ? 78.676  125.115 85.524  1.00 56.64  ? 264 TYR C OH  1 
ATOM 2741 N N   . SER B 2 270 ? 82.286  130.768 91.252  1.00 55.49  ? 265 SER C N   1 
ATOM 2742 C CA  . SER B 2 270 ? 83.182  131.544 92.095  1.00 57.12  ? 265 SER C CA  1 
ATOM 2743 C C   . SER B 2 270 ? 82.651  131.553 93.520  1.00 59.76  ? 265 SER C C   1 
ATOM 2744 O O   . SER B 2 270 ? 81.462  131.337 93.764  1.00 60.04  ? 265 SER C O   1 
ATOM 2745 C CB  . SER B 2 270 ? 83.338  132.983 91.585  1.00 58.08  ? 265 SER C CB  1 
ATOM 2746 O OG  . SER B 2 270 ? 82.083  133.635 91.499  1.00 56.11  ? 265 SER C OG  1 
ATOM 2747 N N   . HIS B 2 271 ? 83.556  131.799 94.463  1.00 82.10  ? 266 HIS C N   1 
ATOM 2748 C CA  . HIS B 2 271 ? 83.190  131.959 95.862  1.00 83.09  ? 266 HIS C CA  1 
ATOM 2749 C C   . HIS B 2 271 ? 84.231  132.840 96.536  1.00 85.25  ? 266 HIS C C   1 
ATOM 2750 O O   . HIS B 2 271 ? 85.431  132.683 96.300  1.00 86.09  ? 266 HIS C O   1 
ATOM 2751 C CB  . HIS B 2 271 ? 83.088  130.606 96.575  1.00 81.70  ? 266 HIS C CB  1 
ATOM 2752 C CG  . HIS B 2 271 ? 82.589  130.701 97.982  1.00 84.00  ? 266 HIS C CG  1 
ATOM 2753 N ND1 . HIS B 2 271 ? 82.861  129.742 98.935  1.00 86.97  ? 266 HIS C ND1 1 
ATOM 2754 C CD2 . HIS B 2 271 ? 81.830  131.638 98.598  1.00 83.11  ? 266 HIS C CD2 1 
ATOM 2755 C CE1 . HIS B 2 271 ? 82.294  130.087 100.077 1.00 85.79  ? 266 HIS C CE1 1 
ATOM 2756 N NE2 . HIS B 2 271 ? 81.663  131.234 99.900  1.00 83.59  ? 266 HIS C NE2 1 
ATOM 2757 N N   . ASP B 2 272 ? 83.761  133.765 97.377  1.00 93.17  ? 267 ASP C N   1 
ATOM 2758 C CA  . ASP B 2 272 ? 84.660  134.721 98.013  1.00 92.89  ? 267 ASP C CA  1 
ATOM 2759 C C   . ASP B 2 272 ? 85.685  134.047 98.914  1.00 92.48  ? 267 ASP C C   1 
ATOM 2760 O O   . ASP B 2 272 ? 86.777  134.593 99.104  1.00 92.80  ? 267 ASP C O   1 
ATOM 2761 C CB  . ASP B 2 272 ? 83.853  135.738 98.819  1.00 92.32  ? 267 ASP C CB  1 
ATOM 2762 C CG  . ASP B 2 272 ? 82.998  136.630 97.941  1.00 93.61  ? 267 ASP C CG  1 
ATOM 2763 O OD1 . ASP B 2 272 ? 83.098  136.521 96.702  1.00 93.16  ? 267 ASP C OD1 1 
ATOM 2764 O OD2 . ASP B 2 272 ? 82.224  137.440 98.493  1.00 92.47  ? 267 ASP C OD2 1 
ATOM 2765 N N   . ASN B 2 273 ? 85.367  132.876 99.471  1.00 84.35  ? 268 ASN C N   1 
ATOM 2766 C CA  . ASN B 2 273 ? 86.327  132.192 100.331 1.00 84.37  ? 268 ASN C CA  1 
ATOM 2767 C C   . ASN B 2 273 ? 87.563  131.762 99.550  1.00 84.01  ? 268 ASN C C   1 
ATOM 2768 O O   . ASN B 2 273 ? 88.690  131.893 100.042 1.00 85.74  ? 268 ASN C O   1 
ATOM 2769 C CB  . ASN B 2 273 ? 85.671  130.983 100.997 1.00 84.98  ? 268 ASN C CB  1 
ATOM 2770 C CG  . ASN B 2 273 ? 84.770  131.370 102.153 1.00 85.88  ? 268 ASN C CG  1 
ATOM 2771 O OD1 . ASN B 2 273 ? 84.764  132.519 102.594 1.00 86.13  ? 268 ASN C OD1 1 
ATOM 2772 N ND2 . ASN B 2 273 ? 84.010  130.405 102.658 1.00 85.14  ? 268 ASN C ND2 1 
ATOM 2773 N N   . ILE B 2 274 ? 87.375  131.253 98.336  1.00 74.58  ? 269 ILE C N   1 
ATOM 2774 C CA  . ILE B 2 274 ? 88.475  130.793 97.494  1.00 76.67  ? 269 ILE C CA  1 
ATOM 2775 C C   . ILE B 2 274 ? 88.779  131.908 96.500  1.00 73.36  ? 269 ILE C C   1 
ATOM 2776 O O   . ILE B 2 274 ? 88.012  132.155 95.566  1.00 72.84  ? 269 ILE C O   1 
ATOM 2777 C CB  . ILE B 2 274 ? 88.147  129.474 96.783  1.00 74.35  ? 269 ILE C CB  1 
ATOM 2778 C CG1 . ILE B 2 274 ? 86.762  129.519 96.136  1.00 73.12  ? 269 ILE C CG1 1 
ATOM 2779 C CG2 . ILE B 2 274 ? 88.220  128.304 97.753  1.00 71.89  ? 269 ILE C CG2 1 
ATOM 2780 C CD1 . ILE B 2 274 ? 86.491  128.359 95.229  1.00 69.19  ? 269 ILE C CD1 1 
ATOM 2781 N N   . ILE B 2 275 ? 89.895  132.603 96.709  1.00 70.70  ? 270 ILE C N   1 
ATOM 2782 C CA  . ILE B 2 275 ? 90.386  133.559 95.724  1.00 72.12  ? 270 ILE C CA  1 
ATOM 2783 C C   . ILE B 2 275 ? 91.851  133.245 95.444  1.00 71.03  ? 270 ILE C C   1 
ATOM 2784 O O   . ILE B 2 275 ? 92.755  133.773 96.099  1.00 70.62  ? 270 ILE C O   1 
ATOM 2785 C CB  . ILE B 2 275 ? 90.173  135.012 96.201  1.00 70.18  ? 270 ILE C CB  1 
ATOM 2786 C CG1 . ILE B 2 275 ? 90.671  136.014 95.151  1.00 70.36  ? 270 ILE C CG1 1 
ATOM 2787 C CG2 . ILE B 2 275 ? 90.808  135.259 97.576  1.00 68.70  ? 270 ILE C CG2 1 
ATOM 2788 C CD1 . ILE B 2 275 ? 89.751  136.134 93.958  1.00 68.53  ? 270 ILE C CD1 1 
ATOM 2789 N N   . CYS B 2 276 ? 92.082  132.394 94.453  1.00 59.14  ? 271 CYS C N   1 
ATOM 2790 C CA  . CYS B 2 276 ? 93.409  131.960 94.036  1.00 57.24  ? 271 CYS C CA  1 
ATOM 2791 C C   . CYS B 2 276 ? 93.289  131.460 92.598  1.00 54.86  ? 271 CYS C C   1 
ATOM 2792 O O   . CYS B 2 276 ? 92.322  131.778 91.899  1.00 57.29  ? 271 CYS C O   1 
ATOM 2793 C CB  . CYS B 2 276 ? 93.960  130.906 95.016  1.00 56.95  ? 271 CYS C CB  1 
ATOM 2794 S SG  . CYS B 2 276 ? 94.565  131.592 96.578  1.00 59.95  ? 271 CYS C SG  1 
ATOM 2795 N N   . GLY B 2 277 ? 94.279  130.699 92.141  1.00 42.94  ? 272 GLY C N   1 
ATOM 2796 C CA  . GLY B 2 277 ? 94.226  130.155 90.803  1.00 44.11  ? 272 GLY C CA  1 
ATOM 2797 C C   . GLY B 2 277 ? 93.451  128.851 90.719  1.00 42.32  ? 272 GLY C C   1 
ATOM 2798 O O   . GLY B 2 277 ? 93.172  128.188 91.716  1.00 40.96  ? 272 GLY C O   1 
ATOM 2799 N N   . ILE B 2 278 ? 93.095  128.492 89.488  1.00 40.54  ? 273 ILE C N   1 
ATOM 2800 C CA  . ILE B 2 278 ? 92.548  127.181 89.156  1.00 31.12  ? 273 ILE C CA  1 
ATOM 2801 C C   . ILE B 2 278 ? 93.567  126.492 88.263  1.00 33.59  ? 273 ILE C C   1 
ATOM 2802 O O   . ILE B 2 278 ? 93.954  127.029 87.220  1.00 38.35  ? 273 ILE C O   1 
ATOM 2803 C CB  . ILE B 2 278 ? 91.180  127.287 88.467  1.00 31.81  ? 273 ILE C CB  1 
ATOM 2804 C CG1 . ILE B 2 278 ? 90.157  127.844 89.453  1.00 37.67  ? 273 ILE C CG1 1 
ATOM 2805 C CG2 . ILE B 2 278 ? 90.733  125.926 87.927  1.00 26.73  ? 273 ILE C CG2 1 
ATOM 2806 C CD1 . ILE B 2 278 ? 88.738  127.809 88.965  1.00 33.19  ? 273 ILE C CD1 1 
ATOM 2807 N N   . THR B 2 279 ? 93.998  125.300 88.671  1.00 30.12  ? 274 THR C N   1 
ATOM 2808 C CA  . THR B 2 279 ? 95.105  124.619 88.022  1.00 31.22  ? 274 THR C CA  1 
ATOM 2809 C C   . THR B 2 279 ? 94.687  123.425 87.177  1.00 30.88  ? 274 THR C C   1 
ATOM 2810 O O   . THR B 2 279 ? 95.489  122.958 86.364  1.00 33.48  ? 274 THR C O   1 
ATOM 2811 C CB  . THR B 2 279 ? 96.118  124.155 89.078  1.00 26.07  ? 274 THR C CB  1 
ATOM 2812 O OG1 . THR B 2 279 ? 95.526  123.150 89.908  1.00 23.92  ? 274 THR C OG1 1 
ATOM 2813 C CG2 . THR B 2 279 ? 96.542  125.324 89.945  1.00 27.41  ? 274 THR C CG2 1 
ATOM 2814 N N   . SER B 2 280 ? 93.463  122.929 87.339  1.00 23.46  ? 275 SER C N   1 
ATOM 2815 C CA  . SER B 2 280 ? 92.988  121.796 86.565  1.00 7.02   ? 275 SER C CA  1 
ATOM 2816 C C   . SER B 2 280 ? 91.470  121.844 86.508  1.00 17.91  ? 275 SER C C   1 
ATOM 2817 O O   . SER B 2 280 ? 90.819  122.493 87.329  1.00 30.22  ? 275 SER C O   1 
ATOM 2818 C CB  . SER B 2 280 ? 93.472  120.477 87.164  1.00 12.02  ? 275 SER C CB  1 
ATOM 2819 O OG  . SER B 2 280 ? 93.337  120.489 88.571  1.00 21.79  ? 275 SER C OG  1 
ATOM 2820 N N   . VAL B 2 281 ? 90.912  121.163 85.513  1.00 31.62  ? 276 VAL C N   1 
ATOM 2821 C CA  . VAL B 2 281 ? 89.466  121.092 85.320  1.00 30.12  ? 276 VAL C CA  1 
ATOM 2822 C C   . VAL B 2 281 ? 89.145  119.748 84.684  1.00 36.71  ? 276 VAL C C   1 
ATOM 2823 O O   . VAL B 2 281 ? 89.919  119.232 83.873  1.00 38.69  ? 276 VAL C O   1 
ATOM 2824 C CB  . VAL B 2 281 ? 88.944  122.262 84.451  1.00 27.87  ? 276 VAL C CB  1 
ATOM 2825 C CG1 . VAL B 2 281 ? 87.492  122.043 84.057  1.00 26.58  ? 276 VAL C CG1 1 
ATOM 2826 C CG2 . VAL B 2 281 ? 89.092  123.590 85.181  1.00 29.65  ? 276 VAL C CG2 1 
ATOM 2827 N N   . SER B 2 282 ? 88.007  119.173 85.061  1.00 30.69  ? 277 SER C N   1 
ATOM 2828 C CA  . SER B 2 282 ? 87.581  117.908 84.486  1.00 23.09  ? 277 SER C CA  1 
ATOM 2829 C C   . SER B 2 282 ? 86.110  117.685 84.790  1.00 26.78  ? 277 SER C C   1 
ATOM 2830 O O   . SER B 2 282 ? 85.658  117.941 85.906  1.00 33.33  ? 277 SER C O   1 
ATOM 2831 C CB  . SER B 2 282 ? 88.411  116.750 85.036  1.00 19.54  ? 277 SER C CB  1 
ATOM 2832 O OG  . SER B 2 282 ? 87.954  115.520 84.513  1.00 31.67  ? 277 SER C OG  1 
ATOM 2833 N N   . PHE B 2 283 ? 85.373  117.204 83.797  1.00 34.16  ? 278 PHE C N   1 
ATOM 2834 C CA  . PHE B 2 283 ? 83.981  116.831 83.981  1.00 32.94  ? 278 PHE C CA  1 
ATOM 2835 C C   . PHE B 2 283 ? 83.915  115.392 84.491  1.00 40.38  ? 278 PHE C C   1 
ATOM 2836 O O   . PHE B 2 283 ? 84.931  114.782 84.831  1.00 43.48  ? 278 PHE C O   1 
ATOM 2837 C CB  . PHE B 2 283 ? 83.205  117.007 82.676  1.00 35.95  ? 278 PHE C CB  1 
ATOM 2838 C CG  . PHE B 2 283 ? 82.734  118.410 82.431  1.00 41.11  ? 278 PHE C CG  1 
ATOM 2839 C CD1 . PHE B 2 283 ? 81.590  118.885 83.043  1.00 42.25  ? 278 PHE C CD1 1 
ATOM 2840 C CD2 . PHE B 2 283 ? 83.425  119.247 81.576  1.00 37.27  ? 278 PHE C CD2 1 
ATOM 2841 C CE1 . PHE B 2 283 ? 81.151  120.170 82.815  1.00 38.63  ? 278 PHE C CE1 1 
ATOM 2842 C CE2 . PHE B 2 283 ? 82.990  120.532 81.344  1.00 33.08  ? 278 PHE C CE2 1 
ATOM 2843 C CZ  . PHE B 2 283 ? 81.852  120.993 81.964  1.00 40.09  ? 278 PHE C CZ  1 
ATOM 2844 N N   . SER B 2 284 ? 82.714  114.837 84.554  1.00 41.57  ? 279 SER C N   1 
ATOM 2845 C CA  . SER B 2 284 ? 82.488  113.442 84.894  1.00 40.34  ? 279 SER C CA  1 
ATOM 2846 C C   . SER B 2 284 ? 81.717  112.776 83.759  1.00 41.26  ? 279 SER C C   1 
ATOM 2847 O O   . SER B 2 284 ? 81.394  113.402 82.749  1.00 50.87  ? 279 SER C O   1 
ATOM 2848 C CB  . SER B 2 284 ? 81.749  113.323 86.229  1.00 43.98  ? 279 SER C CB  1 
ATOM 2849 O OG  . SER B 2 284 ? 82.617  113.627 87.305  1.00 41.39  ? 279 SER C OG  1 
ATOM 2850 N N   . LYS B 2 285 ? 81.412  111.492 83.937  1.00 44.14  ? 280 LYS C N   1 
ATOM 2851 C CA  . LYS B 2 285 ? 80.871  110.699 82.840  1.00 47.64  ? 280 LYS C CA  1 
ATOM 2852 C C   . LYS B 2 285 ? 79.563  111.260 82.299  1.00 49.02  ? 280 LYS C C   1 
ATOM 2853 O O   . LYS B 2 285 ? 79.232  111.010 81.135  1.00 46.15  ? 280 LYS C O   1 
ATOM 2854 C CB  . LYS B 2 285 ? 80.668  109.256 83.298  1.00 47.77  ? 280 LYS C CB  1 
ATOM 2855 C CG  . LYS B 2 285 ? 80.456  108.277 82.165  1.00 46.06  ? 280 LYS C CG  1 
ATOM 2856 C CD  . LYS B 2 285 ? 80.381  106.856 82.677  1.00 49.26  ? 280 LYS C CD  1 
ATOM 2857 C CE  . LYS B 2 285 ? 80.122  105.873 81.554  1.00 49.99  ? 280 LYS C CE  1 
ATOM 2858 N NZ  . LYS B 2 285 ? 78.822  106.127 80.879  1.00 51.84  ? 280 LYS C NZ  1 
ATOM 2859 N N   . SER B 2 286 ? 78.815  112.011 83.108  1.00 51.65  ? 281 SER C N   1 
ATOM 2860 C CA  . SER B 2 286 ? 77.529  112.554 82.697  1.00 52.36  ? 281 SER C CA  1 
ATOM 2861 C C   . SER B 2 286 ? 77.535  114.066 82.528  1.00 55.85  ? 281 SER C C   1 
ATOM 2862 O O   . SER B 2 286 ? 76.588  114.610 81.948  1.00 57.44  ? 281 SER C O   1 
ATOM 2863 C CB  . SER B 2 286 ? 76.447  112.170 83.716  1.00 56.50  ? 281 SER C CB  1 
ATOM 2864 O OG  . SER B 2 286 ? 76.709  112.757 84.977  1.00 54.96  ? 281 SER C OG  1 
ATOM 2865 N N   . GLY B 2 287 ? 78.567  114.756 83.007  1.00 49.35  ? 282 GLY C N   1 
ATOM 2866 C CA  . GLY B 2 287 ? 78.616  116.198 82.942  1.00 47.84  ? 282 GLY C CA  1 
ATOM 2867 C C   . GLY B 2 287 ? 77.843  116.909 84.028  1.00 49.68  ? 282 GLY C C   1 
ATOM 2868 O O   . GLY B 2 287 ? 77.786  118.144 84.017  1.00 48.57  ? 282 GLY C O   1 
ATOM 2869 N N   . ARG B 2 288 ? 77.240  116.173 84.962  1.00 56.23  ? 283 ARG C N   1 
ATOM 2870 C CA  . ARG B 2 288 ? 76.523  116.785 86.072  1.00 49.99  ? 283 ARG C CA  1 
ATOM 2871 C C   . ARG B 2 288 ? 77.457  117.302 87.157  1.00 48.15  ? 283 ARG C C   1 
ATOM 2872 O O   . ARG B 2 288 ? 77.042  118.136 87.967  1.00 49.54  ? 283 ARG C O   1 
ATOM 2873 C CB  . ARG B 2 288 ? 75.543  115.773 86.669  1.00 52.20  ? 283 ARG C CB  1 
ATOM 2874 C CG  . ARG B 2 288 ? 74.626  116.325 87.750  1.00 55.70  ? 283 ARG C CG  1 
ATOM 2875 C CD  . ARG B 2 288 ? 73.724  117.423 87.217  1.00 57.60  ? 283 ARG C CD  1 
ATOM 2876 N NE  . ARG B 2 288 ? 72.561  117.639 88.071  1.00 56.94  ? 283 ARG C NE  1 
ATOM 2877 C CZ  . ARG B 2 288 ? 72.553  118.401 89.156  1.00 55.33  ? 283 ARG C CZ  1 
ATOM 2878 N NH1 . ARG B 2 288 ? 73.639  119.032 89.570  1.00 56.18  ? 283 ARG C NH1 1 
ATOM 2879 N NH2 . ARG B 2 288 ? 71.423  118.533 89.845  1.00 54.44  ? 283 ARG C NH2 1 
ATOM 2880 N N   . LEU B 2 289 ? 78.700  116.828 87.191  1.00 38.54  ? 284 LEU C N   1 
ATOM 2881 C CA  . LEU B 2 289 ? 79.672  117.225 88.196  1.00 33.00  ? 284 LEU C CA  1 
ATOM 2882 C C   . LEU B 2 289 ? 80.899  117.794 87.502  1.00 26.69  ? 284 LEU C C   1 
ATOM 2883 O O   . LEU B 2 289 ? 81.207  117.438 86.363  1.00 34.18  ? 284 LEU C O   1 
ATOM 2884 C CB  . LEU B 2 289 ? 80.064  116.038 89.080  1.00 39.07  ? 284 LEU C CB  1 
ATOM 2885 C CG  . LEU B 2 289 ? 80.413  116.328 90.540  1.00 38.17  ? 284 LEU C CG  1 
ATOM 2886 C CD1 . LEU B 2 289 ? 79.200  116.848 91.298  1.00 37.13  ? 284 LEU C CD1 1 
ATOM 2887 C CD2 . LEU B 2 289 ? 80.959  115.071 91.195  1.00 39.03  ? 284 LEU C CD2 1 
ATOM 2888 N N   . LEU B 2 290 ? 81.598  118.684 88.202  1.00 26.29  ? 285 LEU C N   1 
ATOM 2889 C CA  . LEU B 2 290 ? 82.698  119.451 87.619  1.00 32.69  ? 285 LEU C CA  1 
ATOM 2890 C C   . LEU B 2 290 ? 83.827  119.517 88.640  1.00 24.35  ? 285 LEU C C   1 
ATOM 2891 O O   . LEU B 2 290 ? 83.818  120.372 89.528  1.00 31.68  ? 285 LEU C O   1 
ATOM 2892 C CB  . LEU B 2 290 ? 82.235  120.848 87.217  1.00 30.95  ? 285 LEU C CB  1 
ATOM 2893 C CG  . LEU B 2 290 ? 83.310  121.822 86.731  1.00 26.10  ? 285 LEU C CG  1 
ATOM 2894 C CD1 . LEU B 2 290 ? 83.916  121.345 85.424  1.00 27.56  ? 285 LEU C CD1 1 
ATOM 2895 C CD2 . LEU B 2 290 ? 82.731  123.209 86.578  1.00 30.20  ? 285 LEU C CD2 1 
ATOM 2896 N N   . LEU B 2 291 ? 84.802  118.629 88.501  1.00 15.68  ? 286 LEU C N   1 
ATOM 2897 C CA  . LEU B 2 291 ? 85.966  118.679 89.362  1.00 14.59  ? 286 LEU C CA  1 
ATOM 2898 C C   . LEU B 2 291 ? 86.791  119.921 89.048  1.00 12.96  ? 286 LEU C C   1 
ATOM 2899 O O   . LEU B 2 291 ? 86.567  120.616 88.057  1.00 29.71  ? 286 LEU C O   1 
ATOM 2900 C CB  . LEU B 2 291 ? 86.810  117.417 89.191  1.00 27.20  ? 286 LEU C CB  1 
ATOM 2901 C CG  . LEU B 2 291 ? 86.422  116.177 90.001  1.00 22.01  ? 286 LEU C CG  1 
ATOM 2902 C CD1 . LEU B 2 291 ? 86.853  116.342 91.444  1.00 10.67  ? 286 LEU C CD1 1 
ATOM 2903 C CD2 . LEU B 2 291 ? 84.936  115.893 89.905  1.00 19.50  ? 286 LEU C CD2 1 
ATOM 2904 N N   . ALA B 2 292 ? 87.744  120.214 89.926  1.00 21.02  ? 287 ALA C N   1 
ATOM 2905 C CA  . ALA B 2 292 ? 88.653  121.333 89.720  1.00 26.88  ? 287 ALA C CA  1 
ATOM 2906 C C   . ALA B 2 292 ? 89.820  121.185 90.683  1.00 30.91  ? 287 ALA C C   1 
ATOM 2907 O O   . ALA B 2 292 ? 89.781  120.386 91.618  1.00 46.87  ? 287 ALA C O   1 
ATOM 2908 C CB  . ALA B 2 292 ? 87.944  122.679 89.914  1.00 25.22  ? 287 ALA C CB  1 
ATOM 2909 N N   . GLY B 2 293 ? 90.861  121.966 90.438  1.00 10.46  ? 288 GLY C N   1 
ATOM 2910 C CA  . GLY B 2 293 ? 92.011  121.995 91.315  1.00 18.24  ? 288 GLY C CA  1 
ATOM 2911 C C   . GLY B 2 293 ? 92.435  123.425 91.560  1.00 33.23  ? 288 GLY C C   1 
ATOM 2912 O O   . GLY B 2 293 ? 92.266  124.299 90.711  1.00 26.28  ? 288 GLY C O   1 
ATOM 2913 N N   . TYR B 2 294 ? 92.985  123.657 92.749  1.00 40.40  ? 289 TYR C N   1 
ATOM 2914 C CA  . TYR B 2 294 ? 93.380  124.991 93.176  1.00 35.41  ? 289 TYR C CA  1 
ATOM 2915 C C   . TYR B 2 294 ? 94.777  124.948 93.772  1.00 33.58  ? 289 TYR C C   1 
ATOM 2916 O O   . TYR B 2 294 ? 95.294  123.889 94.132  1.00 24.50  ? 289 TYR C O   1 
ATOM 2917 C CB  . TYR B 2 294 ? 92.407  125.572 94.207  1.00 28.34  ? 289 TYR C CB  1 
ATOM 2918 C CG  . TYR B 2 294 ? 90.997  125.729 93.706  1.00 26.08  ? 289 TYR C CG  1 
ATOM 2919 C CD1 . TYR B 2 294 ? 90.142  124.644 93.643  1.00 30.75  ? 289 TYR C CD1 1 
ATOM 2920 C CD2 . TYR B 2 294 ? 90.516  126.964 93.306  1.00 30.64  ? 289 TYR C CD2 1 
ATOM 2921 C CE1 . TYR B 2 294 ? 88.853  124.780 93.188  1.00 24.09  ? 289 TYR C CE1 1 
ATOM 2922 C CE2 . TYR B 2 294 ? 89.226  127.110 92.853  1.00 30.31  ? 289 TYR C CE2 1 
ATOM 2923 C CZ  . TYR B 2 294 ? 88.400  126.013 92.796  1.00 27.50  ? 289 TYR C CZ  1 
ATOM 2924 O OH  . TYR B 2 294 ? 87.113  126.146 92.344  1.00 39.45  ? 289 TYR C OH  1 
ATOM 2925 N N   . ASP B 2 295 ? 95.388  126.126 93.861  1.00 39.42  ? 290 ASP C N   1 
ATOM 2926 C CA  . ASP B 2 295 ? 96.640  126.258 94.585  1.00 42.79  ? 290 ASP C CA  1 
ATOM 2927 C C   . ASP B 2 295 ? 96.457  126.086 96.087  1.00 46.82  ? 290 ASP C C   1 
ATOM 2928 O O   . ASP B 2 295 ? 97.456  125.991 96.808  1.00 48.48  ? 290 ASP C O   1 
ATOM 2929 C CB  . ASP B 2 295 ? 97.271  127.619 94.290  1.00 46.27  ? 290 ASP C CB  1 
ATOM 2930 C CG  . ASP B 2 295 ? 97.543  127.826 92.814  1.00 48.49  ? 290 ASP C CG  1 
ATOM 2931 O OD1 . ASP B 2 295 ? 96.577  128.030 92.050  1.00 40.75  ? 290 ASP C OD1 1 
ATOM 2932 O OD2 . ASP B 2 295 ? 98.727  127.786 92.416  1.00 49.42  ? 290 ASP C OD2 1 
ATOM 2933 N N   . ASP B 2 296 ? 95.218  126.049 96.574  1.00 46.97  ? 291 ASP C N   1 
ATOM 2934 C CA  . ASP B 2 296 ? 94.943  125.849 97.996  1.00 44.18  ? 291 ASP C CA  1 
ATOM 2935 C C   . ASP B 2 296 ? 94.845  124.366 98.344  1.00 44.56  ? 291 ASP C C   1 
ATOM 2936 O O   . ASP B 2 296 ? 93.938  123.931 99.049  1.00 48.13  ? 291 ASP C O   1 
ATOM 2937 C CB  . ASP B 2 296 ? 93.658  126.575 98.371  1.00 48.67  ? 291 ASP C CB  1 
ATOM 2938 C CG  . ASP B 2 296 ? 93.819  128.080 98.372  1.00 53.69  ? 291 ASP C CG  1 
ATOM 2939 O OD1 . ASP B 2 296 ? 94.976  128.546 98.364  1.00 48.87  ? 291 ASP C OD1 1 
ATOM 2940 O OD2 . ASP B 2 296 ? 92.794  128.792 98.376  1.00 53.58  ? 291 ASP C OD2 1 
ATOM 2941 N N   . PHE B 2 297 ? 95.797  123.581 97.839  1.00 43.93  ? 292 PHE C N   1 
ATOM 2942 C CA  . PHE B 2 297 ? 96.029  122.197 98.262  1.00 42.80  ? 292 PHE C CA  1 
ATOM 2943 C C   . PHE B 2 297 ? 94.754  121.356 98.235  1.00 40.51  ? 292 PHE C C   1 
ATOM 2944 O O   . PHE B 2 297 ? 94.679  120.322 98.903  1.00 45.83  ? 292 PHE C O   1 
ATOM 2945 C CB  . PHE B 2 297 ? 96.660  122.140 99.661  1.00 46.04  ? 292 PHE C CB  1 
ATOM 2946 C CG  . PHE B 2 297 ? 97.990  122.852 99.781  1.00 44.64  ? 292 PHE C CG  1 
ATOM 2947 C CD1 . PHE B 2 297 ? 98.564  123.517 98.707  1.00 45.21  ? 292 PHE C CD1 1 
ATOM 2948 C CD2 . PHE B 2 297 ? 98.671  122.843 100.986 1.00 44.17  ? 292 PHE C CD2 1 
ATOM 2949 C CE1 . PHE B 2 297 ? 99.777  124.162 98.839  1.00 44.69  ? 292 PHE C CE1 1 
ATOM 2950 C CE2 . PHE B 2 297 ? 99.888  123.485 101.119 1.00 45.90  ? 292 PHE C CE2 1 
ATOM 2951 C CZ  . PHE B 2 297 ? 100.439 124.143 100.044 1.00 43.65  ? 292 PHE C CZ  1 
ATOM 2952 N N   . ASN B 2 298 ? 93.744  121.770 97.476  1.00 35.42  ? 293 ASN C N   1 
ATOM 2953 C CA  . ASN B 2 298 ? 92.437  121.129 97.500  1.00 36.60  ? 293 ASN C CA  1 
ATOM 2954 C C   . ASN B 2 298 ? 91.923  120.933 96.081  1.00 37.57  ? 293 ASN C C   1 
ATOM 2955 O O   . ASN B 2 298 ? 92.514  121.405 95.107  1.00 40.99  ? 293 ASN C O   1 
ATOM 2956 C CB  . ASN B 2 298 ? 91.430  121.955 98.315  1.00 36.48  ? 293 ASN C CB  1 
ATOM 2957 C CG  . ASN B 2 298 ? 91.466  121.626 99.795  1.00 39.41  ? 293 ASN C CG  1 
ATOM 2958 O OD1 . ASN B 2 298 ? 92.522  121.335 100.357 1.00 42.82  ? 293 ASN C OD1 1 
ATOM 2959 N ND2 . ASN B 2 298 ? 90.304  121.663 100.434 1.00 35.19  ? 293 ASN C ND2 1 
ATOM 2960 N N   . CYS B 2 299 ? 90.806  120.213 95.977  1.00 26.84  ? 294 CYS C N   1 
ATOM 2961 C CA  . CYS B 2 299 ? 90.101  119.998 94.712  1.00 27.95  ? 294 CYS C CA  1 
ATOM 2962 C C   . CYS B 2 299 ? 88.613  120.141 95.019  1.00 30.74  ? 294 CYS C C   1 
ATOM 2963 O O   . CYS B 2 299 ? 87.943  119.164 95.360  1.00 39.42  ? 294 CYS C O   1 
ATOM 2964 C CB  . CYS B 2 299 ? 90.419  118.635 94.111  1.00 30.50  ? 294 CYS C CB  1 
ATOM 2965 S SG  . CYS B 2 299 ? 92.169  118.284 93.911  1.00 43.94  ? 294 CYS C SG  1 
ATOM 2966 N N   . ASN B 2 300 ? 88.099  121.358 94.897  1.00 26.64  ? 295 ASN C N   1 
ATOM 2967 C CA  . ASN B 2 300 ? 86.698  121.594 95.210  1.00 33.48  ? 295 ASN C CA  1 
ATOM 2968 C C   . ASN B 2 300 ? 85.817  120.991 94.126  1.00 25.92  ? 295 ASN C C   1 
ATOM 2969 O O   . ASN B 2 300 ? 85.998  121.264 92.938  1.00 31.44  ? 295 ASN C O   1 
ATOM 2970 C CB  . ASN B 2 300 ? 86.430  123.091 95.350  1.00 36.22  ? 295 ASN C CB  1 
ATOM 2971 C CG  . ASN B 2 300 ? 86.998  123.668 96.635  1.00 36.19  ? 295 ASN C CG  1 
ATOM 2972 O OD1 . ASN B 2 300 ? 86.267  123.913 97.592  1.00 38.04  ? 295 ASN C OD1 1 
ATOM 2973 N ND2 . ASN B 2 300 ? 88.307  123.883 96.662  1.00 37.97  ? 295 ASN C ND2 1 
ATOM 2974 N N   . VAL B 2 301 ? 84.865  120.160 94.539  1.00 29.87  ? 296 VAL C N   1 
ATOM 2975 C CA  . VAL B 2 301 ? 83.971  119.474 93.615  1.00 32.03  ? 296 VAL C CA  1 
ATOM 2976 C C   . VAL B 2 301 ? 82.773  120.392 93.399  1.00 31.28  ? 296 VAL C C   1 
ATOM 2977 O O   . VAL B 2 301 ? 81.867  120.461 94.228  1.00 35.41  ? 296 VAL C O   1 
ATOM 2978 C CB  . VAL B 2 301 ? 83.553  118.101 94.146  1.00 23.91  ? 296 VAL C CB  1 
ATOM 2979 C CG1 . VAL B 2 301 ? 82.666  117.386 93.146  1.00 21.10  ? 296 VAL C CG1 1 
ATOM 2980 C CG2 . VAL B 2 301 ? 84.775  117.260 94.476  1.00 22.30  ? 296 VAL C CG2 1 
ATOM 2981 N N   . TRP B 2 302 ? 82.767  121.094 92.275  1.00 25.49  ? 297 TRP C N   1 
ATOM 2982 C CA  . TRP B 2 302 ? 81.701  122.031 91.963  1.00 29.92  ? 297 TRP C CA  1 
ATOM 2983 C C   . TRP B 2 302 ? 80.469  121.264 91.499  1.00 27.53  ? 297 TRP C C   1 
ATOM 2984 O O   . TRP B 2 302 ? 80.396  120.037 91.587  1.00 36.60  ? 297 TRP C O   1 
ATOM 2985 C CB  . TRP B 2 302 ? 82.182  123.031 90.917  1.00 34.42  ? 297 TRP C CB  1 
ATOM 2986 C CG  . TRP B 2 302 ? 83.035  124.088 91.496  1.00 37.18  ? 297 TRP C CG  1 
ATOM 2987 C CD1 . TRP B 2 302 ? 84.394  124.115 91.533  1.00 31.59  ? 297 TRP C CD1 1 
ATOM 2988 C CD2 . TRP B 2 302 ? 82.589  125.282 92.147  1.00 42.08  ? 297 TRP C CD2 1 
ATOM 2989 N NE1 . TRP B 2 302 ? 84.824  125.254 92.164  1.00 38.77  ? 297 TRP C NE1 1 
ATOM 2990 C CE2 . TRP B 2 302 ? 83.734  125.987 92.551  1.00 38.73  ? 297 TRP C CE2 1 
ATOM 2991 C CE3 . TRP B 2 302 ? 81.331  125.823 92.424  1.00 36.31  ? 297 TRP C CE3 1 
ATOM 2992 C CZ2 . TRP B 2 302 ? 83.660  127.204 93.217  1.00 37.56  ? 297 TRP C CZ2 1 
ATOM 2993 C CZ3 . TRP B 2 302 ? 81.262  127.028 93.082  1.00 33.96  ? 297 TRP C CZ3 1 
ATOM 2994 C CH2 . TRP B 2 302 ? 82.416  127.706 93.471  1.00 36.83  ? 297 TRP C CH2 1 
ATOM 2995 N N   . ASP B 2 303 ? 79.472  121.993 91.017  1.00 39.99  ? 298 ASP C N   1 
ATOM 2996 C CA  . ASP B 2 303 ? 78.316  121.419 90.353  1.00 46.58  ? 298 ASP C CA  1 
ATOM 2997 C C   . ASP B 2 303 ? 78.083  122.196 89.065  1.00 52.89  ? 298 ASP C C   1 
ATOM 2998 O O   . ASP B 2 303 ? 78.417  123.379 88.970  1.00 55.61  ? 298 ASP C O   1 
ATOM 2999 C CB  . ASP B 2 303 ? 77.079  121.458 91.260  1.00 49.22  ? 298 ASP C CB  1 
ATOM 3000 C CG  . ASP B 2 303 ? 75.873  120.786 90.638  1.00 52.39  ? 298 ASP C CG  1 
ATOM 3001 O OD1 . ASP B 2 303 ? 76.016  120.168 89.563  1.00 55.71  ? 298 ASP C OD1 1 
ATOM 3002 O OD2 . ASP B 2 303 ? 74.777  120.873 91.228  1.00 53.71  ? 298 ASP C OD2 1 
ATOM 3003 N N   . ALA B 2 304 ? 77.523  121.520 88.064  1.00 53.07  ? 299 ALA C N   1 
ATOM 3004 C CA  . ALA B 2 304 ? 77.439  122.091 86.723  1.00 50.85  ? 299 ALA C CA  1 
ATOM 3005 C C   . ALA B 2 304 ? 76.174  122.921 86.533  1.00 56.34  ? 299 ALA C C   1 
ATOM 3006 O O   . ALA B 2 304 ? 76.247  124.120 86.250  1.00 61.22  ? 299 ALA C O   1 
ATOM 3007 C CB  . ALA B 2 304 ? 77.500  120.974 85.677  1.00 53.09  ? 299 ALA C CB  1 
ATOM 3008 N N   . LEU B 2 305 ? 75.008  122.294 86.688  1.00 64.18  ? 300 LEU C N   1 
ATOM 3009 C CA  . LEU B 2 305 ? 73.754  122.979 86.393  1.00 65.25  ? 300 LEU C CA  1 
ATOM 3010 C C   . LEU B 2 305 ? 73.537  124.164 87.325  1.00 67.41  ? 300 LEU C C   1 
ATOM 3011 O O   . LEU B 2 305 ? 73.087  125.231 86.891  1.00 65.72  ? 300 LEU C O   1 
ATOM 3012 C CB  . LEU B 2 305 ? 72.592  121.991 86.491  1.00 66.07  ? 300 LEU C CB  1 
ATOM 3013 C CG  . LEU B 2 305 ? 72.787  120.685 85.715  1.00 66.17  ? 300 LEU C CG  1 
ATOM 3014 C CD1 . LEU B 2 305 ? 71.540  119.821 85.797  1.00 66.78  ? 300 LEU C CD1 1 
ATOM 3015 C CD2 . LEU B 2 305 ? 73.167  120.960 84.266  1.00 64.91  ? 300 LEU C CD2 1 
ATOM 3016 N N   . LYS B 2 306 ? 73.847  123.995 88.606  1.00 67.99  ? 301 LYS C N   1 
ATOM 3017 C CA  . LYS B 2 306 ? 73.761  125.060 89.593  1.00 66.22  ? 301 LYS C CA  1 
ATOM 3018 C C   . LYS B 2 306 ? 75.131  125.266 90.220  1.00 65.87  ? 301 LYS C C   1 
ATOM 3019 O O   . LYS B 2 306 ? 75.794  124.305 90.617  1.00 63.24  ? 301 LYS C O   1 
ATOM 3020 C CB  . LYS B 2 306 ? 72.721  124.734 90.669  1.00 65.74  ? 301 LYS C CB  1 
ATOM 3021 C CG  . LYS B 2 306 ? 72.893  123.366 91.317  1.00 67.37  ? 301 LYS C CG  1 
ATOM 3022 C CD  . LYS B 2 306 ? 71.687  122.983 92.168  1.00 66.53  ? 301 LYS C CD  1 
ATOM 3023 C CE  . LYS B 2 306 ? 70.443  122.716 91.328  1.00 68.27  ? 301 LYS C CE  1 
ATOM 3024 N NZ  . LYS B 2 306 ? 70.672  121.704 90.259  1.00 68.54  ? 301 LYS C NZ  1 
ATOM 3025 N N   . ALA B 2 307 ? 75.544  126.528 90.326  1.00 65.28  ? 302 ALA C N   1 
ATOM 3026 C CA  . ALA B 2 307 ? 76.916  126.844 90.701  1.00 64.41  ? 302 ALA C CA  1 
ATOM 3027 C C   . ALA B 2 307 ? 77.258  126.440 92.128  1.00 64.13  ? 302 ALA C C   1 
ATOM 3028 O O   . ALA B 2 307 ? 78.442  126.450 92.480  1.00 65.27  ? 302 ALA C O   1 
ATOM 3029 C CB  . ALA B 2 307 ? 77.170  128.341 90.524  1.00 65.26  ? 302 ALA C CB  1 
ATOM 3030 N N   . ASP B 2 308 ? 76.270  126.089 92.950  1.00 60.05  ? 303 ASP C N   1 
ATOM 3031 C CA  . ASP B 2 308 ? 76.531  125.805 94.355  1.00 59.52  ? 303 ASP C CA  1 
ATOM 3032 C C   . ASP B 2 308 ? 77.563  124.695 94.497  1.00 55.17  ? 303 ASP C C   1 
ATOM 3033 O O   . ASP B 2 308 ? 77.463  123.650 93.850  1.00 60.70  ? 303 ASP C O   1 
ATOM 3034 C CB  . ASP B 2 308 ? 75.233  125.414 95.060  1.00 58.59  ? 303 ASP C CB  1 
ATOM 3035 C CG  . ASP B 2 308 ? 74.178  126.503 94.988  1.00 61.49  ? 303 ASP C CG  1 
ATOM 3036 O OD1 . ASP B 2 308 ? 74.554  127.692 94.918  1.00 62.29  ? 303 ASP C OD1 1 
ATOM 3037 O OD2 . ASP B 2 308 ? 72.975  126.169 95.001  1.00 60.17  ? 303 ASP C OD2 1 
ATOM 3038 N N   . ARG B 2 309 ? 78.551  124.924 95.358  1.00 40.53  ? 304 ARG C N   1 
ATOM 3039 C CA  . ARG B 2 309 ? 79.655  123.990 95.530  1.00 36.33  ? 304 ARG C CA  1 
ATOM 3040 C C   . ARG B 2 309 ? 79.226  122.850 96.443  1.00 41.84  ? 304 ARG C C   1 
ATOM 3041 O O   . ARG B 2 309 ? 78.815  123.082 97.584  1.00 45.14  ? 304 ARG C O   1 
ATOM 3042 C CB  . ARG B 2 309 ? 80.868  124.709 96.109  1.00 39.69  ? 304 ARG C CB  1 
ATOM 3043 C CG  . ARG B 2 309 ? 82.160  123.940 95.973  1.00 39.61  ? 304 ARG C CG  1 
ATOM 3044 C CD  . ARG B 2 309 ? 83.182  124.410 96.980  1.00 42.35  ? 304 ARG C CD  1 
ATOM 3045 N NE  . ARG B 2 309 ? 82.919  123.881 98.312  1.00 49.60  ? 304 ARG C NE  1 
ATOM 3046 C CZ  . ARG B 2 309 ? 83.700  124.080 99.365  1.00 50.02  ? 304 ARG C CZ  1 
ATOM 3047 N NH1 . ARG B 2 309 ? 84.812  124.792 99.279  1.00 44.28  ? 304 ARG C NH1 1 
ATOM 3048 N NH2 . ARG B 2 309 ? 83.357  123.550 100.536 1.00 47.16  ? 304 ARG C NH2 1 
ATOM 3049 N N   . ALA B 2 310 ? 79.333  121.617 95.946  1.00 42.98  ? 305 ALA C N   1 
ATOM 3050 C CA  . ALA B 2 310 ? 78.935  120.420 96.689  1.00 36.70  ? 305 ALA C CA  1 
ATOM 3051 C C   . ALA B 2 310 ? 80.102  119.436 96.679  1.00 33.23  ? 305 ALA C C   1 
ATOM 3052 O O   . ALA B 2 310 ? 80.169  118.551 95.826  1.00 39.29  ? 305 ALA C O   1 
ATOM 3053 C CB  . ALA B 2 310 ? 77.675  119.810 96.089  1.00 37.42  ? 305 ALA C CB  1 
ATOM 3054 N N   . GLY B 2 311 ? 81.016  119.592 97.635  1.00 29.21  ? 306 GLY C N   1 
ATOM 3055 C CA  . GLY B 2 311 ? 82.107  118.653 97.802  1.00 23.36  ? 306 GLY C CA  1 
ATOM 3056 C C   . GLY B 2 311 ? 83.466  119.302 97.939  1.00 20.85  ? 306 GLY C C   1 
ATOM 3057 O O   . GLY B 2 311 ? 83.675  120.424 97.476  1.00 40.03  ? 306 GLY C O   1 
ATOM 3058 N N   . VAL B 2 312 ? 84.395  118.603 98.584  1.00 21.51  ? 307 VAL C N   1 
ATOM 3059 C CA  . VAL B 2 312 ? 85.786  119.031 98.687  1.00 25.73  ? 307 VAL C CA  1 
ATOM 3060 C C   . VAL B 2 312 ? 86.651  117.791 98.841  1.00 38.80  ? 307 VAL C C   1 
ATOM 3061 O O   . VAL B 2 312 ? 86.256  116.823 99.498  1.00 41.55  ? 307 VAL C O   1 
ATOM 3062 C CB  . VAL B 2 312 ? 86.012  119.991 99.875  1.00 37.14  ? 307 VAL C CB  1 
ATOM 3063 C CG1 . VAL B 2 312 ? 87.500  120.257 100.076 1.00 35.78  ? 307 VAL C CG1 1 
ATOM 3064 C CG2 . VAL B 2 312 ? 85.260  121.292 99.669  1.00 42.50  ? 307 VAL C CG2 1 
ATOM 3065 N N   . LEU B 2 313 ? 87.831  117.817 98.227  1.00 30.48  ? 308 LEU C N   1 
ATOM 3066 C CA  . LEU B 2 313 ? 88.843  116.785 98.410  1.00 32.41  ? 308 LEU C CA  1 
ATOM 3067 C C   . LEU B 2 313 ? 90.080  117.429 99.013  1.00 33.77  ? 308 LEU C C   1 
ATOM 3068 O O   . LEU B 2 313 ? 90.594  118.411 98.472  1.00 39.88  ? 308 LEU C O   1 
ATOM 3069 C CB  . LEU B 2 313 ? 89.204  116.100 97.088  1.00 37.92  ? 308 LEU C CB  1 
ATOM 3070 C CG  . LEU B 2 313 ? 88.085  115.783 96.096  1.00 35.99  ? 308 LEU C CG  1 
ATOM 3071 C CD1 . LEU B 2 313 ? 88.668  115.061 94.895  1.00 27.57  ? 308 LEU C CD1 1 
ATOM 3072 C CD2 . LEU B 2 313 ? 86.983  114.959 96.736  1.00 36.93  ? 308 LEU C CD2 1 
ATOM 3073 N N   . ALA B 2 314 ? 90.555  116.880 100.129 1.00 36.15  ? 309 ALA C N   1 
ATOM 3074 C CA  . ALA B 2 314 ? 91.722  117.421 100.825 1.00 39.14  ? 309 ALA C CA  1 
ATOM 3075 C C   . ALA B 2 314 ? 92.567  116.249 101.309 1.00 34.27  ? 309 ALA C C   1 
ATOM 3076 O O   . ALA B 2 314 ? 92.326  115.708 102.391 1.00 35.01  ? 309 ALA C O   1 
ATOM 3077 C CB  . ALA B 2 314 ? 91.303  118.318 101.983 1.00 41.46  ? 309 ALA C CB  1 
ATOM 3078 N N   . GLY B 2 315 ? 93.545  115.854 100.500 1.00 37.93  ? 310 GLY C N   1 
ATOM 3079 C CA  . GLY B 2 315 ? 94.430  114.766 100.863 1.00 37.62  ? 310 GLY C CA  1 
ATOM 3080 C C   . GLY B 2 315 ? 95.858  114.951 100.393 1.00 40.00  ? 310 GLY C C   1 
ATOM 3081 O O   . GLY B 2 315 ? 96.616  113.980 100.335 1.00 44.94  ? 310 GLY C O   1 
ATOM 3082 N N   . HIS B 2 316 ? 96.240  116.176 100.044 1.00 37.43  ? 311 HIS C N   1 
ATOM 3083 C CA  . HIS B 2 316 ? 97.547  116.450 99.464  1.00 36.23  ? 311 HIS C CA  1 
ATOM 3084 C C   . HIS B 2 316 ? 98.300  117.470 100.305 1.00 40.00  ? 311 HIS C C   1 
ATOM 3085 O O   . HIS B 2 316 ? 97.730  118.472 100.745 1.00 39.46  ? 311 HIS C O   1 
ATOM 3086 C CB  . HIS B 2 316 ? 97.411  116.954 98.021  1.00 41.19  ? 311 HIS C CB  1 
ATOM 3087 C CG  . HIS B 2 316 ? 97.169  115.865 97.022  1.00 41.84  ? 311 HIS C CG  1 
ATOM 3088 N ND1 . HIS B 2 316 ? 98.136  114.948 96.672  1.00 32.09  ? 311 HIS C ND1 1 
ATOM 3089 C CD2 . HIS B 2 316 ? 96.071  115.548 96.296  1.00 39.76  ? 311 HIS C CD2 1 
ATOM 3090 C CE1 . HIS B 2 316 ? 97.645  114.113 95.775  1.00 27.75  ? 311 HIS C CE1 1 
ATOM 3091 N NE2 . HIS B 2 316 ? 96.394  114.455 95.530  1.00 31.59  ? 311 HIS C NE2 1 
ATOM 3092 N N   . ASP B 2 317 ? 99.588  117.199 100.525 1.00 43.25  ? 312 ASP C N   1 
ATOM 3093 C CA  . ASP B 2 317 ? 100.432 118.123 101.275 1.00 44.26  ? 312 ASP C CA  1 
ATOM 3094 C C   . ASP B 2 317 ? 100.600 119.446 100.539 1.00 49.52  ? 312 ASP C C   1 
ATOM 3095 O O   . ASP B 2 317 ? 100.579 120.515 101.160 1.00 47.20  ? 312 ASP C O   1 
ATOM 3096 C CB  . ASP B 2 317 ? 101.796 117.484 101.535 1.00 46.68  ? 312 ASP C CB  1 
ATOM 3097 C CG  . ASP B 2 317 ? 102.696 118.350 102.395 1.00 52.58  ? 312 ASP C CG  1 
ATOM 3098 O OD1 . ASP B 2 317 ? 102.256 119.443 102.809 1.00 51.56  ? 312 ASP C OD1 1 
ATOM 3099 O OD2 . ASP B 2 317 ? 103.844 117.938 102.660 1.00 48.90  ? 312 ASP C OD2 1 
ATOM 3100 N N   . ASN B 2 318 ? 100.771 119.396 99.223  1.00 44.59  ? 313 ASN C N   1 
ATOM 3101 C CA  . ASN B 2 318 ? 101.015 120.564 98.389  1.00 32.83  ? 313 ASN C CA  1 
ATOM 3102 C C   . ASN B 2 318 ? 99.899  120.677 97.352  1.00 35.46  ? 313 ASN C C   1 
ATOM 3103 O O   . ASN B 2 318 ? 98.975  119.862 97.314  1.00 36.44  ? 313 ASN C O   1 
ATOM 3104 C CB  . ASN B 2 318 ? 102.392 120.464 97.732  1.00 28.35  ? 313 ASN C CB  1 
ATOM 3105 C CG  . ASN B 2 318 ? 102.954 121.810 97.351  1.00 35.60  ? 313 ASN C CG  1 
ATOM 3106 O OD1 . ASN B 2 318 ? 102.226 122.694 96.907  1.00 35.98  ? 313 ASN C OD1 1 
ATOM 3107 N ND2 . ASN B 2 318 ? 104.259 121.975 97.521  1.00 36.86  ? 313 ASN C ND2 1 
ATOM 3108 N N   . ARG B 2 319 ? 99.984  121.698 96.502  1.00 36.54  ? 314 ARG C N   1 
ATOM 3109 C CA  . ARG B 2 319 ? 98.903  121.957 95.560  1.00 34.73  ? 314 ARG C CA  1 
ATOM 3110 C C   . ARG B 2 319 ? 98.863  120.899 94.462  1.00 35.31  ? 314 ARG C C   1 
ATOM 3111 O O   . ARG B 2 319 ? 99.836  120.188 94.201  1.00 31.98  ? 314 ARG C O   1 
ATOM 3112 C CB  . ARG B 2 319 ? 99.032  123.345 94.936  1.00 34.84  ? 314 ARG C CB  1 
ATOM 3113 C CG  . ARG B 2 319 ? 100.368 123.637 94.297  1.00 36.16  ? 314 ARG C CG  1 
ATOM 3114 C CD  . ARG B 2 319 ? 100.222 124.667 93.194  1.00 34.13  ? 314 ARG C CD  1 
ATOM 3115 N NE  . ARG B 2 319 ? 99.774  124.062 91.946  1.00 32.88  ? 314 ARG C NE  1 
ATOM 3116 C CZ  . ARG B 2 319 ? 99.720  124.693 90.782  1.00 35.88  ? 314 ARG C CZ  1 
ATOM 3117 N NH1 . ARG B 2 319 ? 100.064 125.965 90.667  1.00 34.03  ? 314 ARG C NH1 1 
ATOM 3118 N NH2 . ARG B 2 319 ? 99.306  124.031 89.706  1.00 30.59  ? 314 ARG C NH2 1 
ATOM 3119 N N   . VAL B 2 320 ? 97.710  120.816 93.809  1.00 36.06  ? 315 VAL C N   1 
ATOM 3120 C CA  . VAL B 2 320 ? 97.412  119.767 92.843  1.00 31.04  ? 315 VAL C CA  1 
ATOM 3121 C C   . VAL B 2 320 ? 97.661  120.308 91.441  1.00 25.83  ? 315 VAL C C   1 
ATOM 3122 O O   . VAL B 2 320 ? 97.101  121.340 91.053  1.00 31.91  ? 315 VAL C O   1 
ATOM 3123 C CB  . VAL B 2 320 ? 95.969  119.260 93.001  1.00 28.06  ? 315 VAL C CB  1 
ATOM 3124 C CG1 . VAL B 2 320 ? 95.836  118.475 94.287  1.00 29.45  ? 315 VAL C CG1 1 
ATOM 3125 C CG2 . VAL B 2 320 ? 94.972  120.412 92.988  1.00 27.76  ? 315 VAL C CG2 1 
ATOM 3126 N N   . SER B 2 321 ? 98.516  119.615 90.686  1.00 26.83  ? 316 SER C N   1 
ATOM 3127 C CA  . SER B 2 321 ? 98.816  120.009 89.314  1.00 22.41  ? 316 SER C CA  1 
ATOM 3128 C C   . SER B 2 321 ? 97.824  119.408 88.329  1.00 22.18  ? 316 SER C C   1 
ATOM 3129 O O   . SER B 2 321 ? 97.314  120.102 87.443  1.00 18.98  ? 316 SER C O   1 
ATOM 3130 C CB  . SER B 2 321 ? 100.229 119.570 88.938  1.00 24.65  ? 316 SER C CB  1 
ATOM 3131 O OG  . SER B 2 321 ? 101.175 119.997 89.887  1.00 18.59  ? 316 SER C OG  1 
ATOM 3132 N N   . CYS B 2 322 ? 97.553  118.114 88.466  1.00 30.90  ? 317 CYS C N   1 
ATOM 3133 C CA  . CYS B 2 322 ? 96.838  117.338 87.470  1.00 23.25  ? 317 CYS C CA  1 
ATOM 3134 C C   . CYS B 2 322 ? 95.590  116.712 88.073  1.00 25.66  ? 317 CYS C C   1 
ATOM 3135 O O   . CYS B 2 322 ? 95.490  116.505 89.284  1.00 25.51  ? 317 CYS C O   1 
ATOM 3136 C CB  . CYS B 2 322 ? 97.743  116.253 86.892  1.00 14.90  ? 317 CYS C CB  1 
ATOM 3137 S SG  . CYS B 2 322 ? 98.462  115.177 88.153  1.00 45.64  ? 317 CYS C SG  1 
ATOM 3138 N N   . LEU B 2 323 ? 94.633  116.414 87.199  1.00 26.13  ? 318 LEU C N   1 
ATOM 3139 C CA  . LEU B 2 323 ? 93.320  115.938 87.622  1.00 21.66  ? 318 LEU C CA  1 
ATOM 3140 C C   . LEU B 2 323 ? 92.662  115.248 86.439  1.00 23.19  ? 318 LEU C C   1 
ATOM 3141 O O   . LEU B 2 323 ? 92.378  115.901 85.431  1.00 14.80  ? 318 LEU C O   1 
ATOM 3142 C CB  . LEU B 2 323 ? 92.473  117.107 88.117  1.00 17.10  ? 318 LEU C CB  1 
ATOM 3143 C CG  . LEU B 2 323 ? 91.272  116.810 89.009  1.00 24.62  ? 318 LEU C CG  1 
ATOM 3144 C CD1 . LEU B 2 323 ? 90.945  118.038 89.829  1.00 18.33  ? 318 LEU C CD1 1 
ATOM 3145 C CD2 . LEU B 2 323 ? 90.073  116.383 88.188  1.00 23.31  ? 318 LEU C CD2 1 
ATOM 3146 N N   . GLY B 2 324 ? 92.415  113.950 86.559  1.00 19.09  ? 319 GLY C N   1 
ATOM 3147 C CA  . GLY B 2 324 ? 91.861  113.181 85.460  1.00 12.50  ? 319 GLY C CA  1 
ATOM 3148 C C   . GLY B 2 324 ? 90.770  112.246 85.929  1.00 5.92   ? 319 GLY C C   1 
ATOM 3149 O O   . GLY B 2 324 ? 90.807  111.722 87.040  1.00 19.20  ? 319 GLY C O   1 
ATOM 3150 N N   . VAL B 2 325 ? 89.795  112.032 85.049  1.00 13.45  ? 320 VAL C N   1 
ATOM 3151 C CA  . VAL B 2 325 ? 88.648  111.168 85.303  1.00 22.52  ? 320 VAL C CA  1 
ATOM 3152 C C   . VAL B 2 325 ? 88.628  110.090 84.229  1.00 23.46  ? 320 VAL C C   1 
ATOM 3153 O O   . VAL B 2 325 ? 88.758  110.392 83.038  1.00 26.87  ? 320 VAL C O   1 
ATOM 3154 C CB  . VAL B 2 325 ? 87.327  111.962 85.306  1.00 22.31  ? 320 VAL C CB  1 
ATOM 3155 C CG1 . VAL B 2 325 ? 86.141  111.039 85.563  1.00 20.33  ? 320 VAL C CG1 1 
ATOM 3156 C CG2 . VAL B 2 325 ? 87.368  113.086 86.338  1.00 17.75  ? 320 VAL C CG2 1 
ATOM 3157 N N   . THR B 2 326 ? 88.451  108.839 84.648  1.00 29.99  ? 321 THR C N   1 
ATOM 3158 C CA  . THR B 2 326 ? 88.535  107.719 83.727  1.00 20.25  ? 321 THR C CA  1 
ATOM 3159 C C   . THR B 2 326 ? 87.451  107.821 82.657  1.00 35.56  ? 321 THR C C   1 
ATOM 3160 O O   . THR B 2 326 ? 86.558  108.667 82.713  1.00 42.12  ? 321 THR C O   1 
ATOM 3161 C CB  . THR B 2 326 ? 88.395  106.391 84.473  1.00 21.11  ? 321 THR C CB  1 
ATOM 3162 O OG1 . THR B 2 326 ? 87.078  106.276 85.012  1.00 23.52  ? 321 THR C OG1 1 
ATOM 3163 C CG2 . THR B 2 326 ? 89.403  106.281 85.601  1.00 16.25  ? 321 THR C CG2 1 
ATOM 3164 N N   . ASP B 2 327 ? 87.548  106.941 81.657  1.00 40.49  ? 322 ASP C N   1 
ATOM 3165 C CA  . ASP B 2 327 ? 86.523  106.879 80.622  1.00 41.09  ? 322 ASP C CA  1 
ATOM 3166 C C   . ASP B 2 327 ? 85.256  106.192 81.113  1.00 44.77  ? 322 ASP C C   1 
ATOM 3167 O O   . ASP B 2 327 ? 84.168  106.472 80.599  1.00 43.19  ? 322 ASP C O   1 
ATOM 3168 C CB  . ASP B 2 327 ? 87.059  106.155 79.385  1.00 43.01  ? 322 ASP C CB  1 
ATOM 3169 C CG  . ASP B 2 327 ? 87.727  107.096 78.392  1.00 47.21  ? 322 ASP C CG  1 
ATOM 3170 O OD1 . ASP B 2 327 ? 87.701  108.325 78.609  1.00 49.94  ? 322 ASP C OD1 1 
ATOM 3171 O OD2 . ASP B 2 327 ? 88.277  106.600 77.386  1.00 48.95  ? 322 ASP C OD2 1 
ATOM 3172 N N   . ASP B 2 328 ? 85.372  105.297 82.092  1.00 44.45  ? 323 ASP C N   1 
ATOM 3173 C CA  . ASP B 2 328 ? 84.223  104.605 82.662  1.00 45.24  ? 323 ASP C CA  1 
ATOM 3174 C C   . ASP B 2 328 ? 83.688  105.281 83.921  1.00 46.10  ? 323 ASP C C   1 
ATOM 3175 O O   . ASP B 2 328 ? 82.780  104.742 84.559  1.00 48.45  ? 323 ASP C O   1 
ATOM 3176 C CB  . ASP B 2 328 ? 84.582  103.148 82.967  1.00 42.60  ? 323 ASP C CB  1 
ATOM 3177 C CG  . ASP B 2 328 ? 85.812  103.018 83.839  1.00 47.11  ? 323 ASP C CG  1 
ATOM 3178 O OD1 . ASP B 2 328 ? 86.685  103.908 83.769  1.00 44.52  ? 323 ASP C OD1 1 
ATOM 3179 O OD2 . ASP B 2 328 ? 85.910  102.025 84.590  1.00 47.83  ? 323 ASP C OD2 1 
ATOM 3180 N N   . GLY B 2 329 ? 84.232  106.437 84.295  1.00 34.22  ? 324 GLY C N   1 
ATOM 3181 C CA  . GLY B 2 329 ? 83.713  107.180 85.426  1.00 34.62  ? 324 GLY C CA  1 
ATOM 3182 C C   . GLY B 2 329 ? 83.878  106.487 86.757  1.00 36.04  ? 324 GLY C C   1 
ATOM 3183 O O   . GLY B 2 329 ? 83.111  106.751 87.685  1.00 40.74  ? 324 GLY C O   1 
ATOM 3184 N N   . MET B 2 330 ? 84.869  105.611 86.880  1.00 42.98  ? 325 MET C N   1 
ATOM 3185 C CA  . MET B 2 330 ? 85.044  104.820 88.089  1.00 41.53  ? 325 MET C CA  1 
ATOM 3186 C C   . MET B 2 330 ? 85.877  105.535 89.143  1.00 34.28  ? 325 MET C C   1 
ATOM 3187 O O   . MET B 2 330 ? 85.589  105.412 90.337  1.00 38.97  ? 325 MET C O   1 
ATOM 3188 C CB  . MET B 2 330 ? 85.694  103.478 87.739  1.00 35.85  ? 325 MET C CB  1 
ATOM 3189 C CG  . MET B 2 330 ? 85.611  102.430 88.836  1.00 37.58  ? 325 MET C CG  1 
ATOM 3190 S SD  . MET B 2 330 ? 83.926  101.967 89.286  1.00 54.02  ? 325 MET C SD  1 
ATOM 3191 C CE  . MET B 2 330 ? 83.255  101.448 87.708  1.00 41.33  ? 325 MET C CE  1 
ATOM 3192 N N   . ALA B 2 331 ? 86.902  106.282 88.741  1.00 16.65  ? 326 ALA C N   1 
ATOM 3193 C CA  . ALA B 2 331 ? 87.828  106.871 89.694  1.00 18.28  ? 326 ALA C CA  1 
ATOM 3194 C C   . ALA B 2 331 ? 88.311  108.225 89.196  1.00 28.82  ? 326 ALA C C   1 
ATOM 3195 O O   . ALA B 2 331 ? 88.068  108.623 88.056  1.00 24.11  ? 326 ALA C O   1 
ATOM 3196 C CB  . ALA B 2 331 ? 89.021  105.950 89.948  1.00 6.64   ? 326 ALA C CB  1 
ATOM 3197 N N   . VAL B 2 332 ? 88.999  108.934 90.088  1.00 31.58  ? 327 VAL C N   1 
ATOM 3198 C CA  . VAL B 2 332 ? 89.583  110.242 89.815  1.00 15.36  ? 327 VAL C CA  1 
ATOM 3199 C C   . VAL B 2 332 ? 91.003  110.222 90.366  1.00 20.16  ? 327 VAL C C   1 
ATOM 3200 O O   . VAL B 2 332 ? 91.197  110.167 91.585  1.00 20.47  ? 327 VAL C O   1 
ATOM 3201 C CB  . VAL B 2 332 ? 88.769  111.383 90.445  1.00 17.36  ? 327 VAL C CB  1 
ATOM 3202 C CG1 . VAL B 2 332 ? 89.358  112.732 90.084  1.00 18.99  ? 327 VAL C CG1 1 
ATOM 3203 C CG2 . VAL B 2 332 ? 87.322  111.302 90.008  1.00 25.99  ? 327 VAL C CG2 1 
ATOM 3204 N N   . ALA B 2 333 ? 91.990  110.259 89.482  1.00 9.43   ? 328 ALA C N   1 
ATOM 3205 C CA  . ALA B 2 333 ? 93.378  110.357 89.899  1.00 10.90  ? 328 ALA C CA  1 
ATOM 3206 C C   . ALA B 2 333 ? 93.767  111.817 90.069  1.00 16.44  ? 328 ALA C C   1 
ATOM 3207 O O   . ALA B 2 333 ? 93.256  112.700 89.376  1.00 9.49   ? 328 ALA C O   1 
ATOM 3208 C CB  . ALA B 2 333 ? 94.299  109.683 88.885  1.00 17.42  ? 328 ALA C CB  1 
ATOM 3209 N N   . THR B 2 334 ? 94.682  112.067 91.005  1.00 28.47  ? 329 THR C N   1 
ATOM 3210 C CA  . THR B 2 334 ? 95.043  113.436 91.373  1.00 21.11  ? 329 THR C CA  1 
ATOM 3211 C C   . THR B 2 334 ? 96.515  113.443 91.775  1.00 25.25  ? 329 THR C C   1 
ATOM 3212 O O   . THR B 2 334 ? 96.851  113.103 92.912  1.00 34.14  ? 329 THR C O   1 
ATOM 3213 C CB  . THR B 2 334 ? 94.154  113.948 92.502  1.00 27.95  ? 329 THR C CB  1 
ATOM 3214 O OG1 . THR B 2 334 ? 92.783  113.925 92.088  1.00 27.57  ? 329 THR C OG1 1 
ATOM 3215 C CG2 . THR B 2 334 ? 94.525  115.366 92.889  1.00 33.56  ? 329 THR C CG2 1 
ATOM 3216 N N   . GLY B 2 335 ? 97.379  113.828 90.847  1.00 31.39  ? 330 GLY C N   1 
ATOM 3217 C CA  . GLY B 2 335 ? 98.754  114.096 91.194  1.00 28.13  ? 330 GLY C CA  1 
ATOM 3218 C C   . GLY B 2 335 ? 98.923  115.479 91.787  1.00 31.99  ? 330 GLY C C   1 
ATOM 3219 O O   . GLY B 2 335 ? 98.088  116.364 91.615  1.00 12.15  ? 330 GLY C O   1 
ATOM 3220 N N   . SER B 2 336 ? 100.033 115.670 92.495  1.00 34.24  ? 331 SER C N   1 
ATOM 3221 C CA  . SER B 2 336 ? 100.245 116.907 93.228  1.00 31.41  ? 331 SER C CA  1 
ATOM 3222 C C   . SER B 2 336 ? 101.735 117.177 93.358  1.00 32.17  ? 331 SER C C   1 
ATOM 3223 O O   . SER B 2 336 ? 102.575 116.346 93.007  1.00 32.72  ? 331 SER C O   1 
ATOM 3224 C CB  . SER B 2 336 ? 99.591  116.849 94.609  1.00 37.12  ? 331 SER C CB  1 
ATOM 3225 O OG  . SER B 2 336 ? 99.977  117.954 95.404  1.00 43.20  ? 331 SER C OG  1 
ATOM 3226 N N   . TRP B 2 337 ? 102.049 118.361 93.884  1.00 30.92  ? 332 TRP C N   1 
ATOM 3227 C CA  . TRP B 2 337 ? 103.427 118.799 94.077  1.00 33.88  ? 332 TRP C CA  1 
ATOM 3228 C C   . TRP B 2 337 ? 104.118 118.103 95.240  1.00 35.24  ? 332 TRP C C   1 
ATOM 3229 O O   . TRP B 2 337 ? 105.289 118.399 95.500  1.00 31.69  ? 332 TRP C O   1 
ATOM 3230 C CB  . TRP B 2 337 ? 103.462 120.315 94.290  1.00 27.86  ? 332 TRP C CB  1 
ATOM 3231 C CG  . TRP B 2 337 ? 103.336 121.103 93.030  1.00 28.03  ? 332 TRP C CG  1 
ATOM 3232 C CD1 . TRP B 2 337 ? 103.054 120.619 91.796  1.00 31.22  ? 332 TRP C CD1 1 
ATOM 3233 C CD2 . TRP B 2 337 ? 103.498 122.520 92.878  1.00 31.96  ? 332 TRP C CD2 1 
ATOM 3234 N NE1 . TRP B 2 337 ? 103.025 121.640 90.878  1.00 36.03  ? 332 TRP C NE1 1 
ATOM 3235 C CE2 . TRP B 2 337 ? 103.297 122.818 91.518  1.00 34.99  ? 332 TRP C CE2 1 
ATOM 3236 C CE3 . TRP B 2 337 ? 103.796 123.563 93.759  1.00 26.66  ? 332 TRP C CE3 1 
ATOM 3237 C CZ2 . TRP B 2 337 ? 103.381 124.113 91.018  1.00 32.27  ? 332 TRP C CZ2 1 
ATOM 3238 C CZ3 . TRP B 2 337 ? 103.879 124.847 93.260  1.00 29.37  ? 332 TRP C CZ3 1 
ATOM 3239 C CH2 . TRP B 2 337 ? 103.673 125.112 91.903  1.00 32.29  ? 332 TRP C CH2 1 
ATOM 3240 N N   . ASP B 2 338 ? 103.439 117.196 95.938  1.00 32.24  ? 333 ASP C N   1 
ATOM 3241 C CA  . ASP B 2 338 ? 104.031 116.453 97.041  1.00 31.48  ? 333 ASP C CA  1 
ATOM 3242 C C   . ASP B 2 338 ? 104.672 115.143 96.596  1.00 35.70  ? 333 ASP C C   1 
ATOM 3243 O O   . ASP B 2 338 ? 105.152 114.385 97.444  1.00 40.81  ? 333 ASP C O   1 
ATOM 3244 C CB  . ASP B 2 338 ? 102.977 116.175 98.115  1.00 37.16  ? 333 ASP C CB  1 
ATOM 3245 C CG  . ASP B 2 338 ? 101.773 115.437 97.575  1.00 37.89  ? 333 ASP C CG  1 
ATOM 3246 O OD1 . ASP B 2 338 ? 101.734 115.174 96.359  1.00 41.13  ? 333 ASP C OD1 1 
ATOM 3247 O OD2 . ASP B 2 338 ? 100.864 115.118 98.366  1.00 40.05  ? 333 ASP C OD2 1 
ATOM 3248 N N   . SER B 2 339 ? 104.694 114.864 95.292  1.00 32.04  ? 334 SER C N   1 
ATOM 3249 C CA  . SER B 2 339 ? 105.309 113.671 94.715  1.00 26.79  ? 334 SER C CA  1 
ATOM 3250 C C   . SER B 2 339 ? 104.503 112.405 94.970  1.00 27.14  ? 334 SER C C   1 
ATOM 3251 O O   . SER B 2 339 ? 105.031 111.299 94.840  1.00 37.88  ? 334 SER C O   1 
ATOM 3252 C CB  . SER B 2 339 ? 106.740 113.484 95.226  1.00 28.98  ? 334 SER C CB  1 
ATOM 3253 O OG  . SER B 2 339 ? 106.751 113.028 96.565  1.00 30.55  ? 334 SER C OG  1 
ATOM 3254 N N   . PHE B 2 340 ? 103.230 112.539 95.326  1.00 14.84  ? 335 PHE C N   1 
ATOM 3255 C CA  . PHE B 2 340 ? 102.320 111.412 95.443  1.00 26.16  ? 335 PHE C CA  1 
ATOM 3256 C C   . PHE B 2 340 ? 101.108 111.694 94.574  1.00 31.76  ? 335 PHE C C   1 
ATOM 3257 O O   . PHE B 2 340 ? 100.795 112.847 94.270  1.00 31.79  ? 335 PHE C O   1 
ATOM 3258 C CB  . PHE B 2 340 ? 101.862 111.170 96.893  1.00 37.04  ? 335 PHE C CB  1 
ATOM 3259 C CG  . PHE B 2 340 ? 102.987 111.051 97.877  1.00 37.47  ? 335 PHE C CG  1 
ATOM 3260 C CD1 . PHE B 2 340 ? 103.689 109.867 98.005  1.00 31.81  ? 335 PHE C CD1 1 
ATOM 3261 C CD2 . PHE B 2 340 ? 103.335 112.121 98.683  1.00 35.82  ? 335 PHE C CD2 1 
ATOM 3262 C CE1 . PHE B 2 340 ? 104.721 109.756 98.907  1.00 33.71  ? 335 PHE C CE1 1 
ATOM 3263 C CE2 . PHE B 2 340 ? 104.368 112.014 99.588  1.00 33.42  ? 335 PHE C CE2 1 
ATOM 3264 C CZ  . PHE B 2 340 ? 105.060 110.830 99.700  1.00 35.63  ? 335 PHE C CZ  1 
ATOM 3265 N N   . LEU B 2 341 ? 100.430 110.630 94.162  1.00 24.76  ? 336 LEU C N   1 
ATOM 3266 C CA  . LEU B 2 341 ? 99.161  110.783 93.475  1.00 21.29  ? 336 LEU C CA  1 
ATOM 3267 C C   . LEU B 2 341 ? 98.210  109.712 93.977  1.00 11.44  ? 336 LEU C C   1 
ATOM 3268 O O   . LEU B 2 341 ? 98.582  108.544 94.099  1.00 21.38  ? 336 LEU C O   1 
ATOM 3269 C CB  . LEU B 2 341 ? 99.334  110.724 91.951  1.00 33.83  ? 336 LEU C CB  1 
ATOM 3270 C CG  . LEU B 2 341 ? 99.592  109.410 91.219  1.00 17.78  ? 336 LEU C CG  1 
ATOM 3271 C CD1 . LEU B 2 341 ? 98.290  108.773 90.726  1.00 18.03  ? 336 LEU C CD1 1 
ATOM 3272 C CD2 . LEU B 2 341 ? 100.533 109.677 90.071  1.00 12.23  ? 336 LEU C CD2 1 
ATOM 3273 N N   . LYS B 2 342 ? 96.990  110.128 94.283  1.00 16.54  ? 337 LYS C N   1 
ATOM 3274 C CA  . LYS B 2 342 ? 95.996  109.280 94.913  1.00 23.24  ? 337 LYS C CA  1 
ATOM 3275 C C   . LYS B 2 342 ? 94.881  108.989 93.925  1.00 19.32  ? 337 LYS C C   1 
ATOM 3276 O O   . LYS B 2 342 ? 94.696  109.698 92.933  1.00 15.14  ? 337 LYS C O   1 
ATOM 3277 C CB  . LYS B 2 342 ? 95.390  109.937 96.160  1.00 30.90  ? 337 LYS C CB  1 
ATOM 3278 C CG  . LYS B 2 342 ? 96.270  110.932 96.887  1.00 16.76  ? 337 LYS C CG  1 
ATOM 3279 C CD  . LYS B 2 342 ? 97.427  110.249 97.578  1.00 31.35  ? 337 LYS C CD  1 
ATOM 3280 C CE  . LYS B 2 342 ? 98.118  111.181 98.548  1.00 30.80  ? 337 LYS C CE  1 
ATOM 3281 N NZ  . LYS B 2 342 ? 97.216  111.597 99.659  1.00 33.64  ? 337 LYS C NZ  1 
ATOM 3282 N N   . ILE B 2 343 ? 94.130  107.937 94.216  1.00 18.69  ? 338 ILE C N   1 
ATOM 3283 C CA  . ILE B 2 343 ? 92.926  107.602 93.477  1.00 15.88  ? 338 ILE C CA  1 
ATOM 3284 C C   . ILE B 2 343 ? 91.750  107.765 94.425  1.00 20.54  ? 338 ILE C C   1 
ATOM 3285 O O   . ILE B 2 343 ? 91.745  107.202 95.524  1.00 17.10  ? 338 ILE C O   1 
ATOM 3286 C CB  . ILE B 2 343 ? 93.006  106.185 92.889  1.00 17.23  ? 338 ILE C CB  1 
ATOM 3287 C CG1 . ILE B 2 343 ? 94.167  106.130 91.898  1.00 13.28  ? 338 ILE C CG1 1 
ATOM 3288 C CG2 . ILE B 2 343 ? 91.721  105.835 92.189  1.00 24.60  ? 338 ILE C CG2 1 
ATOM 3289 C CD1 . ILE B 2 343 ? 94.510  104.776 91.419  1.00 11.76  ? 338 ILE C CD1 1 
ATOM 3290 N N   . TRP B 2 344 ? 90.768  108.552 94.007  1.00 30.54  ? 339 TRP C N   1 
ATOM 3291 C CA  . TRP B 2 344 ? 89.618  108.901 94.822  1.00 25.69  ? 339 TRP C CA  1 
ATOM 3292 C C   . TRP B 2 344 ? 88.371  108.290 94.203  1.00 24.31  ? 339 TRP C C   1 
ATOM 3293 O O   . TRP B 2 344 ? 88.191  108.352 92.984  1.00 33.71  ? 339 TRP C O   1 
ATOM 3294 C CB  . TRP B 2 344 ? 89.466  110.420 94.908  1.00 25.93  ? 339 TRP C CB  1 
ATOM 3295 C CG  . TRP B 2 344 ? 90.657  111.111 95.481  1.00 20.79  ? 339 TRP C CG  1 
ATOM 3296 C CD1 . TRP B 2 344 ? 91.858  111.303 94.875  1.00 25.77  ? 339 TRP C CD1 1 
ATOM 3297 C CD2 . TRP B 2 344 ? 90.760  111.709 96.776  1.00 32.02  ? 339 TRP C CD2 1 
ATOM 3298 N NE1 . TRP B 2 344 ? 92.708  111.978 95.713  1.00 25.71  ? 339 TRP C NE1 1 
ATOM 3299 C CE2 . TRP B 2 344 ? 92.057  112.240 96.888  1.00 22.67  ? 339 TRP C CE2 1 
ATOM 3300 C CE3 . TRP B 2 344 ? 89.882  111.847 97.852  1.00 30.45  ? 339 TRP C CE3 1 
ATOM 3301 C CZ2 . TRP B 2 344 ? 92.498  112.897 98.031  1.00 28.26  ? 339 TRP C CZ2 1 
ATOM 3302 C CZ3 . TRP B 2 344 ? 90.321  112.495 98.982  1.00 27.74  ? 339 TRP C CZ3 1 
ATOM 3303 C CH2 . TRP B 2 344 ? 91.616  113.012 99.066  1.00 34.91  ? 339 TRP C CH2 1 
ATOM 3304 N N   . ASN B 2 345 ? 87.516  107.706 95.034  1.00 32.04  ? 340 ASN C N   1 
ATOM 3305 C CA  . ASN B 2 345 ? 86.239  107.182 94.553  1.00 37.33  ? 340 ASN C CA  1 
ATOM 3306 C C   . ASN B 2 345 ? 85.146  107.325 95.608  1.00 39.17  ? 340 ASN C C   1 
ATOM 3307 O O   . ASN B 2 345 ? 83.993  107.615 95.293  1.00 31.87  ? 340 ASN C O   1 
ATOM 3308 C CB  . ASN B 2 345 ? 86.372  105.713 94.141  1.00 33.55  ? 340 ASN C CB  1 
ATOM 3309 C CG  . ASN B 2 345 ? 85.206  105.247 93.299  1.00 35.91  ? 340 ASN C CG  1 
ATOM 3310 O OD1 . ASN B 2 345 ? 84.179  105.921 93.209  1.00 41.67  ? 340 ASN C OD1 1 
ATOM 3311 N ND2 . ASN B 2 345 ? 85.346  104.085 92.675  1.00 34.72  ? 340 ASN C ND2 1 
ATOM 3312 O OXT . ASN B 2 345 ? 85.377  107.152 96.804  1.00 38.71  ? 340 ASN C OXT 1 
ATOM 3313 N N   . ARG C 3 27  ? 72.974  130.917 65.128  1.00 100.31 ? 27  ARG E N   1 
ATOM 3314 C CA  . ARG C 3 27  ? 73.040  130.767 66.610  1.00 101.50 ? 27  ARG E CA  1 
ATOM 3315 C C   . ARG C 3 27  ? 71.649  130.501 67.173  1.00 101.69 ? 27  ARG E C   1 
ATOM 3316 O O   . ARG C 3 27  ? 70.649  130.954 66.615  1.00 101.42 ? 27  ARG E O   1 
ATOM 3317 C CB  . ARG C 3 27  ? 73.646  132.016 67.252  1.00 101.35 ? 27  ARG E CB  1 
ATOM 3318 C CG  . ARG C 3 27  ? 74.901  132.513 66.556  1.00 101.01 ? 27  ARG E CG  1 
ATOM 3319 C CD  . ARG C 3 27  ? 75.687  133.485 67.416  1.00 101.50 ? 27  ARG E CD  1 
ATOM 3320 N NE  . ARG C 3 27  ? 76.844  134.019 66.706  1.00 102.20 ? 27  ARG E NE  1 
ATOM 3321 C CZ  . ARG C 3 27  ? 77.858  134.649 67.282  1.00 102.05 ? 27  ARG E CZ  1 
ATOM 3322 N NH1 . ARG C 3 27  ? 77.907  134.833 68.591  1.00 102.02 ? 27  ARG E NH1 1 
ATOM 3323 N NH2 . ARG C 3 27  ? 78.852  135.105 66.524  1.00 100.74 ? 27  ARG E NH2 1 
ATOM 3324 N N   . ILE C 3 28  ? 71.592  129.767 68.279  1.00 97.98  ? 28  ILE E N   1 
ATOM 3325 C CA  . ILE C 3 28  ? 70.335  129.368 68.899  1.00 97.93  ? 28  ILE E CA  1 
ATOM 3326 C C   . ILE C 3 28  ? 70.218  130.059 70.250  1.00 98.12  ? 28  ILE E C   1 
ATOM 3327 O O   . ILE C 3 28  ? 71.221  130.414 70.881  1.00 97.32  ? 28  ILE E O   1 
ATOM 3328 C CB  . ILE C 3 28  ? 70.243  127.833 69.044  1.00 97.56  ? 28  ILE E CB  1 
ATOM 3329 C CG1 . ILE C 3 28  ? 70.667  127.153 67.737  1.00 97.88  ? 28  ILE E CG1 1 
ATOM 3330 C CG2 . ILE C 3 28  ? 68.827  127.407 69.413  1.00 98.00  ? 28  ILE E CG2 1 
ATOM 3331 C CD1 . ILE C 3 28  ? 70.545  125.644 67.755  1.00 97.14  ? 28  ILE E CD1 1 
ATOM 3332 N N   . LYS C 3 29  ? 68.979  130.252 70.694  1.00 103.28 ? 29  LYS E N   1 
ATOM 3333 C CA  . LYS C 3 29  ? 68.725  130.957 71.940  1.00 102.84 ? 29  LYS E CA  1 
ATOM 3334 C C   . LYS C 3 29  ? 69.237  130.150 73.127  1.00 103.19 ? 29  LYS E C   1 
ATOM 3335 O O   . LYS C 3 29  ? 69.330  128.920 73.081  1.00 103.81 ? 29  LYS E O   1 
ATOM 3336 C CB  . LYS C 3 29  ? 67.230  131.232 72.108  1.00 102.12 ? 29  LYS E CB  1 
ATOM 3337 C CG  . LYS C 3 29  ? 66.619  132.094 71.011  1.00 102.51 ? 29  LYS E CG  1 
ATOM 3338 C CD  . LYS C 3 29  ? 65.985  131.254 69.911  1.00 103.18 ? 29  LYS E CD  1 
ATOM 3339 C CE  . LYS C 3 29  ? 65.328  132.121 68.853  1.00 104.07 ? 29  LYS E CE  1 
ATOM 3340 N NZ  . LYS C 3 29  ? 64.738  131.304 67.756  1.00 104.57 ? 29  LYS E NZ  1 
ATOM 3341 N N   . VAL C 3 30  ? 69.561  130.862 74.209  1.00 99.58  ? 30  VAL E N   1 
ATOM 3342 C CA  . VAL C 3 30  ? 70.113  130.210 75.393  1.00 100.34 ? 30  VAL E CA  1 
ATOM 3343 C C   . VAL C 3 30  ? 69.134  129.189 75.953  1.00 100.01 ? 30  VAL E C   1 
ATOM 3344 O O   . VAL C 3 30  ? 69.544  128.201 76.574  1.00 99.97  ? 30  VAL E O   1 
ATOM 3345 C CB  . VAL C 3 30  ? 70.487  131.264 76.455  1.00 99.82  ? 30  VAL E CB  1 
ATOM 3346 C CG1 . VAL C 3 30  ? 71.079  130.595 77.688  1.00 99.20  ? 30  VAL E CG1 1 
ATOM 3347 C CG2 . VAL C 3 30  ? 71.456  132.290 75.878  1.00 98.88  ? 30  VAL E CG2 1 
ATOM 3348 N N   . SER C 3 31  ? 67.833  129.407 75.755  1.00 100.00 ? 31  SER E N   1 
ATOM 3349 C CA  . SER C 3 31  ? 66.837  128.496 76.310  1.00 100.64 ? 31  SER E CA  1 
ATOM 3350 C C   . SER C 3 31  ? 67.006  127.088 75.750  1.00 99.48  ? 31  SER E C   1 
ATOM 3351 O O   . SER C 3 31  ? 67.005  126.104 76.499  1.00 99.42  ? 31  SER E O   1 
ATOM 3352 C CB  . SER C 3 31  ? 65.432  129.023 76.020  1.00 100.07 ? 31  SER E CB  1 
ATOM 3353 O OG  . SER C 3 31  ? 64.443  128.130 76.501  1.00 100.08 ? 31  SER E OG  1 
ATOM 3354 N N   . LYS C 3 32  ? 67.155  126.972 74.428  1.00 96.42  ? 32  LYS E N   1 
ATOM 3355 C CA  . LYS C 3 32  ? 67.256  125.651 73.817  1.00 97.36  ? 32  LYS E CA  1 
ATOM 3356 C C   . LYS C 3 32  ? 68.553  124.956 74.213  1.00 98.65  ? 32  LYS E C   1 
ATOM 3357 O O   . LYS C 3 32  ? 68.560  123.749 74.481  1.00 98.37  ? 32  LYS E O   1 
ATOM 3358 C CB  . LYS C 3 32  ? 67.145  125.768 72.298  1.00 97.85  ? 32  LYS E CB  1 
ATOM 3359 C CG  . LYS C 3 32  ? 66.855  124.448 71.604  1.00 97.68  ? 32  LYS E CG  1 
ATOM 3360 C CD  . LYS C 3 32  ? 66.364  124.656 70.182  1.00 98.07  ? 32  LYS E CD  1 
ATOM 3361 C CE  . LYS C 3 32  ? 66.006  123.337 69.519  1.00 98.11  ? 32  LYS E CE  1 
ATOM 3362 N NZ  . LYS C 3 32  ? 67.182  122.429 69.414  1.00 97.45  ? 32  LYS E NZ  1 
ATOM 3363 N N   . ALA C 3 33  ? 69.662  125.699 74.256  1.00 95.17  ? 33  ALA E N   1 
ATOM 3364 C CA  . ALA C 3 33  ? 70.928  125.108 74.680  1.00 94.13  ? 33  ALA E CA  1 
ATOM 3365 C C   . ALA C 3 33  ? 70.852  124.623 76.122  1.00 94.62  ? 33  ALA E C   1 
ATOM 3366 O O   . ALA C 3 33  ? 71.327  123.527 76.446  1.00 92.59  ? 33  ALA E O   1 
ATOM 3367 C CB  . ALA C 3 33  ? 72.058  126.122 74.514  1.00 91.56  ? 33  ALA E CB  1 
ATOM 3368 N N   . ALA C 3 34  ? 70.257  125.428 77.006  1.00 97.36  ? 34  ALA E N   1 
ATOM 3369 C CA  . ALA C 3 34  ? 70.107  125.015 78.395  1.00 95.70  ? 34  ALA E CA  1 
ATOM 3370 C C   . ALA C 3 34  ? 69.231  123.775 78.505  1.00 95.79  ? 34  ALA E C   1 
ATOM 3371 O O   . ALA C 3 34  ? 69.540  122.853 79.269  1.00 94.17  ? 34  ALA E O   1 
ATOM 3372 C CB  . ALA C 3 34  ? 69.524  126.160 79.221  1.00 94.48  ? 34  ALA E CB  1 
ATOM 3373 N N   . ALA C 3 35  ? 68.132  123.733 77.750  1.00 94.60  ? 35  ALA E N   1 
ATOM 3374 C CA  . ALA C 3 35  ? 67.264  122.561 77.782  1.00 93.87  ? 35  ALA E CA  1 
ATOM 3375 C C   . ALA C 3 35  ? 68.006  121.322 77.303  1.00 94.00  ? 35  ALA E C   1 
ATOM 3376 O O   . ALA C 3 35  ? 67.854  120.236 77.875  1.00 92.17  ? 35  ALA E O   1 
ATOM 3377 C CB  . ALA C 3 35  ? 66.022  122.807 76.927  1.00 92.71  ? 35  ALA E CB  1 
ATOM 3378 N N   . ASP C 3 36  ? 68.813  121.466 76.250  1.00 92.10  ? 36  ASP E N   1 
ATOM 3379 C CA  . ASP C 3 36  ? 69.599  120.338 75.760  1.00 92.16  ? 36  ASP E CA  1 
ATOM 3380 C C   . ASP C 3 36  ? 70.593  119.863 76.811  1.00 92.06  ? 36  ASP E C   1 
ATOM 3381 O O   . ASP C 3 36  ? 70.777  118.655 77.001  1.00 92.79  ? 36  ASP E O   1 
ATOM 3382 C CB  . ASP C 3 36  ? 70.324  120.730 74.473  1.00 92.01  ? 36  ASP E CB  1 
ATOM 3383 C CG  . ASP C 3 36  ? 69.371  120.993 73.324  1.00 92.67  ? 36  ASP E CG  1 
ATOM 3384 O OD1 . ASP C 3 36  ? 68.143  120.890 73.533  1.00 93.37  ? 36  ASP E OD1 1 
ATOM 3385 O OD2 . ASP C 3 36  ? 69.848  121.301 72.212  1.00 92.04  ? 36  ASP E OD2 1 
ATOM 3386 N N   . LEU C 3 37  ? 71.249  120.799 77.502  1.00 88.46  ? 37  LEU E N   1 
ATOM 3387 C CA  . LEU C 3 37  ? 72.189  120.410 78.551  1.00 88.37  ? 37  LEU E CA  1 
ATOM 3388 C C   . LEU C 3 37  ? 71.482  119.677 79.685  1.00 89.08  ? 37  LEU E C   1 
ATOM 3389 O O   . LEU C 3 37  ? 71.995  118.675 80.199  1.00 87.77  ? 37  LEU E O   1 
ATOM 3390 C CB  . LEU C 3 37  ? 72.921  121.637 79.090  1.00 87.78  ? 37  LEU E CB  1 
ATOM 3391 C CG  . LEU C 3 37  ? 73.986  122.265 78.192  1.00 88.05  ? 37  LEU E CG  1 
ATOM 3392 C CD1 . LEU C 3 37  ? 74.545  123.514 78.853  1.00 86.49  ? 37  LEU E CD1 1 
ATOM 3393 C CD2 . LEU C 3 37  ? 75.100  121.278 77.878  1.00 86.00  ? 37  LEU E CD2 1 
ATOM 3394 N N   . MET C 3 38  ? 70.314  120.171 80.105  1.00 91.62  ? 38  MET E N   1 
ATOM 3395 C CA  . MET C 3 38  ? 69.571  119.486 81.159  1.00 90.66  ? 38  MET E CA  1 
ATOM 3396 C C   . MET C 3 38  ? 69.172  118.086 80.718  1.00 90.33  ? 38  MET E C   1 
ATOM 3397 O O   . MET C 3 38  ? 69.301  117.123 81.485  1.00 89.25  ? 38  MET E O   1 
ATOM 3398 C CB  . MET C 3 38  ? 68.324  120.282 81.549  1.00 92.24  ? 38  MET E CB  1 
ATOM 3399 C CG  . MET C 3 38  ? 68.585  121.693 82.046  1.00 92.17  ? 38  MET E CG  1 
ATOM 3400 S SD  . MET C 3 38  ? 69.948  121.821 83.214  1.00 97.34  ? 38  MET E SD  1 
ATOM 3401 C CE  . MET C 3 38  ? 70.696  123.349 82.663  1.00 92.97  ? 38  MET E CE  1 
ATOM 3402 N N   . ALA C 3 39  ? 68.681  117.955 79.483  1.00 88.39  ? 39  ALA E N   1 
ATOM 3403 C CA  . ALA C 3 39  ? 68.286  116.646 78.981  1.00 88.22  ? 39  ALA E CA  1 
ATOM 3404 C C   . ALA C 3 39  ? 69.475  115.697 78.947  1.00 86.79  ? 39  ALA E C   1 
ATOM 3405 O O   . ALA C 3 39  ? 69.352  114.520 79.309  1.00 86.68  ? 39  ALA E O   1 
ATOM 3406 C CB  . ALA C 3 39  ? 67.667  116.783 77.591  1.00 88.11  ? 39  ALA E CB  1 
ATOM 3407 N N   . TYR C 3 40  ? 70.639  116.190 78.522  1.00 76.72  ? 40  TYR E N   1 
ATOM 3408 C CA  . TYR C 3 40  ? 71.823  115.340 78.487  1.00 75.12  ? 40  TYR E CA  1 
ATOM 3409 C C   . TYR C 3 40  ? 72.226  114.905 79.890  1.00 77.47  ? 40  TYR E C   1 
ATOM 3410 O O   . TYR C 3 40  ? 72.450  113.716 80.142  1.00 78.35  ? 40  TYR E O   1 
ATOM 3411 C CB  . TYR C 3 40  ? 72.974  116.072 77.800  1.00 75.69  ? 40  TYR E CB  1 
ATOM 3412 C CG  . TYR C 3 40  ? 74.163  115.184 77.533  1.00 77.77  ? 40  TYR E CG  1 
ATOM 3413 C CD1 . TYR C 3 40  ? 74.236  114.415 76.378  1.00 76.53  ? 40  TYR E CD1 1 
ATOM 3414 C CD2 . TYR C 3 40  ? 75.208  115.105 78.440  1.00 74.70  ? 40  TYR E CD2 1 
ATOM 3415 C CE1 . TYR C 3 40  ? 75.320  113.598 76.134  1.00 75.12  ? 40  TYR E CE1 1 
ATOM 3416 C CE2 . TYR C 3 40  ? 76.293  114.294 78.206  1.00 73.81  ? 40  TYR E CE2 1 
ATOM 3417 C CZ  . TYR C 3 40  ? 76.345  113.542 77.052  1.00 75.98  ? 40  TYR E CZ  1 
ATOM 3418 O OH  . TYR C 3 40  ? 77.430  112.731 76.818  1.00 77.50  ? 40  TYR E OH  1 
ATOM 3419 N N   . CYS C 3 41  ? 72.307  115.855 80.827  1.00 78.70  ? 41  CYS E N   1 
ATOM 3420 C CA  . CYS C 3 41  ? 72.771  115.518 82.170  1.00 77.09  ? 41  CYS E CA  1 
ATOM 3421 C C   . CYS C 3 41  ? 71.823  114.547 82.858  1.00 76.29  ? 41  CYS E C   1 
ATOM 3422 O O   . CYS C 3 41  ? 72.269  113.630 83.556  1.00 73.97  ? 41  CYS E O   1 
ATOM 3423 C CB  . CYS C 3 41  ? 72.936  116.780 83.014  1.00 77.96  ? 41  CYS E CB  1 
ATOM 3424 S SG  . CYS C 3 41  ? 74.256  117.877 82.468  1.00 79.77  ? 41  CYS E SG  1 
ATOM 3425 N N   . GLU C 3 42  ? 70.511  114.733 82.688  1.00 83.50  ? 42  GLU E N   1 
ATOM 3426 C CA  . GLU C 3 42  ? 69.571  113.794 83.291  1.00 81.74  ? 42  GLU E CA  1 
ATOM 3427 C C   . GLU C 3 42  ? 69.595  112.450 82.577  1.00 83.24  ? 42  GLU E C   1 
ATOM 3428 O O   . GLU C 3 42  ? 69.347  111.415 83.203  1.00 84.33  ? 42  GLU E O   1 
ATOM 3429 C CB  . GLU C 3 42  ? 68.156  114.379 83.288  1.00 81.77  ? 42  GLU E CB  1 
ATOM 3430 C CG  . GLU C 3 42  ? 67.572  114.653 81.906  1.00 83.50  ? 42  GLU E CG  1 
ATOM 3431 C CD  . GLU C 3 42  ? 67.007  113.416 81.230  1.00 84.06  ? 42  GLU E CD  1 
ATOM 3432 O OE1 . GLU C 3 42  ? 66.727  112.423 81.933  1.00 81.59  ? 42  GLU E OE1 1 
ATOM 3433 O OE2 . GLU C 3 42  ? 66.850  113.437 79.991  1.00 84.40  ? 42  GLU E OE2 1 
ATOM 3434 N N   . ALA C 3 43  ? 69.895  112.444 81.276  1.00 78.45  ? 43  ALA E N   1 
ATOM 3435 C CA  . ALA C 3 43  ? 69.912  111.190 80.532  1.00 76.28  ? 43  ALA E CA  1 
ATOM 3436 C C   . ALA C 3 43  ? 70.991  110.253 81.056  1.00 74.87  ? 43  ALA E C   1 
ATOM 3437 O O   . ALA C 3 43  ? 70.758  109.048 81.207  1.00 75.13  ? 43  ALA E O   1 
ATOM 3438 C CB  . ALA C 3 43  ? 70.123  111.468 79.044  1.00 75.21  ? 43  ALA E CB  1 
ATOM 3439 N N   . HIS C 3 44  ? 72.175  110.788 81.344  1.00 73.43  ? 44  HIS E N   1 
ATOM 3440 C CA  . HIS C 3 44  ? 73.322  109.988 81.746  1.00 74.37  ? 44  HIS E CA  1 
ATOM 3441 C C   . HIS C 3 44  ? 73.549  109.993 83.251  1.00 74.35  ? 44  HIS E C   1 
ATOM 3442 O O   . HIS C 3 44  ? 74.604  109.538 83.705  1.00 74.24  ? 44  HIS E O   1 
ATOM 3443 C CB  . HIS C 3 44  ? 74.579  110.485 81.031  1.00 71.49  ? 44  HIS E CB  1 
ATOM 3444 C CG  . HIS C 3 44  ? 74.550  110.275 79.549  1.00 73.47  ? 44  HIS E CG  1 
ATOM 3445 N ND1 . HIS C 3 44  ? 75.469  110.848 78.698  1.00 73.82  ? 44  HIS E ND1 1 
ATOM 3446 C CD2 . HIS C 3 44  ? 73.714  109.551 78.769  1.00 73.62  ? 44  HIS E CD2 1 
ATOM 3447 C CE1 . HIS C 3 44  ? 75.200  110.486 77.456  1.00 74.44  ? 44  HIS E CE1 1 
ATOM 3448 N NE2 . HIS C 3 44  ? 74.139  109.700 77.471  1.00 75.08  ? 44  HIS E NE2 1 
ATOM 3449 N N   . ALA C 3 45  ? 72.599  110.496 84.034  1.00 74.58  ? 45  ALA E N   1 
ATOM 3450 C CA  . ALA C 3 45  ? 72.734  110.497 85.491  1.00 73.92  ? 45  ALA E CA  1 
ATOM 3451 C C   . ALA C 3 45  ? 72.123  109.244 86.108  1.00 75.86  ? 45  ALA E C   1 
ATOM 3452 O O   . ALA C 3 45  ? 71.340  109.302 87.054  1.00 76.63  ? 45  ALA E O   1 
ATOM 3453 C CB  . ALA C 3 45  ? 72.099  111.754 86.071  1.00 76.17  ? 45  ALA E CB  1 
ATOM 3454 N N   . LYS C 3 46  ? 72.487  108.089 85.555  1.00 77.45  ? 46  LYS E N   1 
ATOM 3455 C CA  . LYS C 3 46  ? 72.264  106.807 86.211  1.00 75.81  ? 46  LYS E CA  1 
ATOM 3456 C C   . LYS C 3 46  ? 73.448  105.868 86.073  1.00 75.97  ? 46  LYS E C   1 
ATOM 3457 O O   . LYS C 3 46  ? 73.504  104.870 86.796  1.00 76.53  ? 46  LYS E O   1 
ATOM 3458 C CB  . LYS C 3 46  ? 71.009  106.116 85.654  1.00 75.23  ? 46  LYS E CB  1 
ATOM 3459 C CG  . LYS C 3 46  ? 71.144  105.586 84.225  1.00 74.92  ? 46  LYS E CG  1 
ATOM 3460 C CD  . LYS C 3 46  ? 69.971  104.695 83.831  1.00 76.35  ? 46  LYS E CD  1 
ATOM 3461 C CE  . LYS C 3 46  ? 69.895  103.422 84.669  1.00 77.30  ? 46  LYS E CE  1 
ATOM 3462 N NZ  . LYS C 3 46  ? 71.200  102.707 84.760  1.00 76.69  ? 46  LYS E NZ  1 
ATOM 3463 N N   . GLU C 3 47  ? 74.390  106.151 85.175  1.00 66.30  ? 47  GLU E N   1 
ATOM 3464 C CA  . GLU C 3 47  ? 75.574  105.335 84.953  1.00 65.62  ? 47  GLU E CA  1 
ATOM 3465 C C   . GLU C 3 47  ? 76.839  106.129 85.252  1.00 65.69  ? 47  GLU E C   1 
ATOM 3466 O O   . GLU C 3 47  ? 77.871  105.930 84.612  1.00 64.62  ? 47  GLU E O   1 
ATOM 3467 C CB  . GLU C 3 47  ? 75.602  104.809 83.519  1.00 64.91  ? 47  GLU E CB  1 
ATOM 3468 C CG  . GLU C 3 47  ? 75.561  105.901 82.462  1.00 65.96  ? 47  GLU E CG  1 
ATOM 3469 C CD  . GLU C 3 47  ? 75.576  105.352 81.051  1.00 67.71  ? 47  GLU E CD  1 
ATOM 3470 O OE1 . GLU C 3 47  ? 75.471  104.117 80.891  1.00 67.73  ? 47  GLU E OE1 1 
ATOM 3471 O OE2 . GLU C 3 47  ? 75.694  106.154 80.102  1.00 63.78  ? 47  GLU E OE2 1 
ATOM 3472 N N   . ASP C 3 48  ? 76.758  107.044 86.217  1.00 61.95  ? 48  ASP E N   1 
ATOM 3473 C CA  . ASP C 3 48  ? 77.879  107.892 86.606  1.00 62.07  ? 48  ASP E CA  1 
ATOM 3474 C C   . ASP C 3 48  ? 78.378  107.443 87.973  1.00 62.25  ? 48  ASP E C   1 
ATOM 3475 O O   . ASP C 3 48  ? 77.767  107.784 88.997  1.00 58.96  ? 48  ASP E O   1 
ATOM 3476 C CB  . ASP C 3 48  ? 77.445  109.361 86.645  1.00 57.74  ? 48  ASP E CB  1 
ATOM 3477 C CG  . ASP C 3 48  ? 78.614  110.315 86.799  1.00 60.32  ? 48  ASP E CG  1 
ATOM 3478 O OD1 . ASP C 3 48  ? 79.755  109.843 86.989  1.00 59.36  ? 48  ASP E OD1 1 
ATOM 3479 O OD2 . ASP C 3 48  ? 78.391  111.541 86.724  1.00 57.90  ? 48  ASP E OD2 1 
ATOM 3480 N N   . PRO C 3 49  ? 79.475  106.679 88.056  1.00 61.90  ? 49  PRO E N   1 
ATOM 3481 C CA  . PRO C 3 49  ? 79.934  106.201 89.368  1.00 57.69  ? 49  PRO E CA  1 
ATOM 3482 C C   . PRO C 3 49  ? 80.690  107.251 90.171  1.00 58.67  ? 49  PRO E C   1 
ATOM 3483 O O   . PRO C 3 49  ? 81.758  106.969 90.725  1.00 56.60  ? 49  PRO E O   1 
ATOM 3484 C CB  . PRO C 3 49  ? 80.841  105.012 89.012  1.00 59.30  ? 49  PRO E CB  1 
ATOM 3485 C CG  . PRO C 3 49  ? 80.581  104.712 87.576  1.00 59.43  ? 49  PRO E CG  1 
ATOM 3486 C CD  . PRO C 3 49  ? 80.175  105.998 86.957  1.00 55.69  ? 49  PRO E CD  1 
ATOM 3487 N N   . LEU C 3 50  ? 80.146  108.465 90.242  1.00 59.69  ? 50  LEU E N   1 
ATOM 3488 C CA  . LEU C 3 50  ? 80.636  109.492 91.154  1.00 56.73  ? 50  LEU E CA  1 
ATOM 3489 C C   . LEU C 3 50  ? 79.526  110.231 91.880  1.00 56.45  ? 50  LEU E C   1 
ATOM 3490 O O   . LEU C 3 50  ? 79.791  110.806 92.942  1.00 56.91  ? 50  LEU E O   1 
ATOM 3491 C CB  . LEU C 3 50  ? 81.502  110.517 90.407  1.00 55.80  ? 50  LEU E CB  1 
ATOM 3492 C CG  . LEU C 3 50  ? 82.873  110.045 89.909  1.00 55.71  ? 50  LEU E CG  1 
ATOM 3493 C CD1 . LEU C 3 50  ? 83.560  111.153 89.129  1.00 51.30  ? 50  LEU E CD1 1 
ATOM 3494 C CD2 . LEU C 3 50  ? 83.757  109.568 91.052  1.00 50.50  ? 50  LEU E CD2 1 
ATOM 3495 N N   . LEU C 3 51  ? 78.304  110.246 91.348  1.00 62.08  ? 51  LEU E N   1 
ATOM 3496 C CA  . LEU C 3 51  ? 77.141  110.729 92.083  1.00 59.38  ? 51  LEU E CA  1 
ATOM 3497 C C   . LEU C 3 51  ? 76.481  109.591 92.857  1.00 60.68  ? 51  LEU E C   1 
ATOM 3498 O O   . LEU C 3 51  ? 76.371  109.645 94.085  1.00 62.84  ? 51  LEU E O   1 
ATOM 3499 C CB  . LEU C 3 51  ? 76.132  111.366 91.122  1.00 57.98  ? 51  LEU E CB  1 
ATOM 3500 C CG  . LEU C 3 51  ? 76.652  112.415 90.141  1.00 59.96  ? 51  LEU E CG  1 
ATOM 3501 C CD1 . LEU C 3 51  ? 75.483  113.049 89.408  1.00 58.82  ? 51  LEU E CD1 1 
ATOM 3502 C CD2 . LEU C 3 51  ? 77.486  113.471 90.845  1.00 62.86  ? 51  LEU E CD2 1 
ATOM 3503 N N   . THR C 3 52  ? 76.039  108.555 92.146  1.00 69.76  ? 52  THR E N   1 
ATOM 3504 C CA  . THR C 3 52  ? 75.433  107.402 92.787  1.00 70.96  ? 52  THR E CA  1 
ATOM 3505 C C   . THR C 3 52  ? 76.505  106.533 93.445  1.00 72.15  ? 52  THR E C   1 
ATOM 3506 O O   . THR C 3 52  ? 77.624  106.427 92.936  1.00 70.97  ? 52  THR E O   1 
ATOM 3507 C CB  . THR C 3 52  ? 74.658  106.570 91.770  1.00 71.88  ? 52  THR E CB  1 
ATOM 3508 O OG1 . THR C 3 52  ? 75.559  106.049 90.787  1.00 72.51  ? 52  THR E OG1 1 
ATOM 3509 C CG2 . THR C 3 52  ? 73.594  107.416 91.082  1.00 70.46  ? 52  THR E CG2 1 
ATOM 3510 N N   . PRO C 3 53  ? 76.192  105.903 94.576  1.00 78.00  ? 53  PRO E N   1 
ATOM 3511 C CA  . PRO C 3 53  ? 77.176  105.025 95.216  1.00 76.71  ? 53  PRO E CA  1 
ATOM 3512 C C   . PRO C 3 53  ? 77.431  103.773 94.392  1.00 75.11  ? 53  PRO E C   1 
ATOM 3513 O O   . PRO C 3 53  ? 76.578  103.318 93.626  1.00 76.45  ? 53  PRO E O   1 
ATOM 3514 C CB  . PRO C 3 53  ? 76.527  104.685 96.562  1.00 76.18  ? 53  PRO E CB  1 
ATOM 3515 C CG  . PRO C 3 53  ? 75.073  104.838 96.327  1.00 75.37  ? 53  PRO E CG  1 
ATOM 3516 C CD  . PRO C 3 53  ? 74.929  105.952 95.332  1.00 76.60  ? 53  PRO E CD  1 
ATOM 3517 N N   . VAL C 3 54  ? 78.624  103.221 94.561  1.00 72.79  ? 54  VAL E N   1 
ATOM 3518 C CA  . VAL C 3 54  ? 79.053  101.995 93.895  1.00 74.92  ? 54  VAL E CA  1 
ATOM 3519 C C   . VAL C 3 54  ? 79.201  100.915 94.962  1.00 75.23  ? 54  VAL E C   1 
ATOM 3520 O O   . VAL C 3 54  ? 79.972  101.101 95.913  1.00 74.06  ? 54  VAL E O   1 
ATOM 3521 C CB  . VAL C 3 54  ? 80.374  102.197 93.134  1.00 74.20  ? 54  VAL E CB  1 
ATOM 3522 C CG1 . VAL C 3 54  ? 80.818  100.900 92.471  1.00 72.58  ? 54  VAL E CG1 1 
ATOM 3523 C CG2 . VAL C 3 54  ? 80.231  103.302 92.101  1.00 72.22  ? 54  VAL E CG2 1 
ATOM 3524 N N   . PRO C 3 55  ? 78.497  99.785  94.859  1.00 74.53  ? 55  PRO E N   1 
ATOM 3525 C CA  . PRO C 3 55  ? 78.666  98.731  95.867  1.00 72.22  ? 55  PRO E CA  1 
ATOM 3526 C C   . PRO C 3 55  ? 80.114  98.268  95.937  1.00 73.09  ? 55  PRO E C   1 
ATOM 3527 O O   . PRO C 3 55  ? 80.809  98.189  94.923  1.00 75.12  ? 55  PRO E O   1 
ATOM 3528 C CB  . PRO C 3 55  ? 77.738  97.614  95.375  1.00 72.72  ? 55  PRO E CB  1 
ATOM 3529 C CG  . PRO C 3 55  ? 76.750  98.291  94.492  1.00 72.76  ? 55  PRO E CG  1 
ATOM 3530 C CD  . PRO C 3 55  ? 77.475  99.429  93.859  1.00 74.16  ? 55  PRO E CD  1 
ATOM 3531 N N   . ALA C 3 56  ? 80.569  97.958  97.155  1.00 68.55  ? 56  ALA E N   1 
ATOM 3532 C CA  . ALA C 3 56  ? 81.940  97.495  97.331  1.00 69.42  ? 56  ALA E CA  1 
ATOM 3533 C C   . ALA C 3 56  ? 82.207  96.214  96.558  1.00 70.33  ? 56  ALA E C   1 
ATOM 3534 O O   . ALA C 3 56  ? 83.366  95.915  96.252  1.00 68.42  ? 56  ALA E O   1 
ATOM 3535 C CB  . ALA C 3 56  ? 82.247  97.264  98.811  1.00 69.62  ? 56  ALA E CB  1 
ATOM 3536 N N   . SER C 3 57  ? 81.163  95.447  96.244  1.00 74.99  ? 57  SER E N   1 
ATOM 3537 C CA  . SER C 3 57  ? 81.334  94.215  95.489  1.00 74.95  ? 57  SER E CA  1 
ATOM 3538 C C   . SER C 3 57  ? 81.574  94.464  94.006  1.00 71.38  ? 57  SER E C   1 
ATOM 3539 O O   . SER C 3 57  ? 81.963  93.529  93.298  1.00 69.57  ? 57  SER E O   1 
ATOM 3540 C CB  . SER C 3 57  ? 80.106  93.324  95.679  1.00 74.32  ? 57  SER E CB  1 
ATOM 3541 O OG  . SER C 3 57  ? 78.933  93.980  95.233  1.00 72.66  ? 57  SER E OG  1 
ATOM 3542 N N   . GLU C 3 58  ? 81.357  95.692  93.522  1.00 64.36  ? 58  GLU E N   1 
ATOM 3543 C CA  . GLU C 3 58  ? 81.609  96.041  92.131  1.00 66.14  ? 58  GLU E CA  1 
ATOM 3544 C C   . GLU C 3 58  ? 82.774  97.008  91.952  1.00 64.70  ? 58  GLU E C   1 
ATOM 3545 O O   . GLU C 3 58  ? 83.398  97.002  90.888  1.00 62.22  ? 58  GLU E O   1 
ATOM 3546 C CB  . GLU C 3 58  ? 80.341  96.651  91.511  1.00 65.51  ? 58  GLU E CB  1 
ATOM 3547 C CG  . GLU C 3 58  ? 80.226  96.521  89.998  1.00 66.50  ? 58  GLU E CG  1 
ATOM 3548 C CD  . GLU C 3 58  ? 81.072  97.531  89.248  1.00 67.15  ? 58  GLU E CD  1 
ATOM 3549 O OE1 . GLU C 3 58  ? 81.423  98.574  89.839  1.00 64.30  ? 58  GLU E OE1 1 
ATOM 3550 O OE2 . GLU C 3 58  ? 81.386  97.281  88.066  1.00 65.98  ? 58  GLU E OE2 1 
ATOM 3551 N N   . ASN C 3 59  ? 83.097  97.805  92.960  1.00 52.30  ? 59  ASN E N   1 
ATOM 3552 C CA  . ASN C 3 59  ? 84.201  98.753  92.858  1.00 45.68  ? 59  ASN E CA  1 
ATOM 3553 C C   . ASN C 3 59  ? 85.514  97.998  92.683  1.00 49.16  ? 59  ASN E C   1 
ATOM 3554 O O   . ASN C 3 59  ? 85.760  97.040  93.425  1.00 57.47  ? 59  ASN E O   1 
ATOM 3555 C CB  . ASN C 3 59  ? 84.259  99.625  94.109  1.00 48.88  ? 59  ASN E CB  1 
ATOM 3556 C CG  . ASN C 3 59  ? 85.085  100.879 93.912  1.00 49.53  ? 59  ASN E CG  1 
ATOM 3557 O OD1 . ASN C 3 59  ? 85.227  101.373 92.795  1.00 50.58  ? 59  ASN E OD1 1 
ATOM 3558 N ND2 . ASN C 3 59  ? 85.634  101.403 95.000  1.00 47.71  ? 59  ASN E ND2 1 
ATOM 3559 N N   . PRO C 3 60  ? 86.359  98.349  91.710  1.00 32.98  ? 60  PRO E N   1 
ATOM 3560 C CA  . PRO C 3 60  ? 87.689  97.737  91.616  1.00 26.79  ? 60  PRO E CA  1 
ATOM 3561 C C   . PRO C 3 60  ? 88.765  98.398  92.464  1.00 29.61  ? 60  PRO E C   1 
ATOM 3562 O O   . PRO C 3 60  ? 89.940  98.061  92.296  1.00 16.85  ? 60  PRO E O   1 
ATOM 3563 C CB  . PRO C 3 60  ? 88.018  97.886  90.124  1.00 26.47  ? 60  PRO E CB  1 
ATOM 3564 C CG  . PRO C 3 60  ? 87.317  99.099  89.715  1.00 32.41  ? 60  PRO E CG  1 
ATOM 3565 C CD  . PRO C 3 60  ? 86.052  99.155  90.515  1.00 38.33  ? 60  PRO E CD  1 
ATOM 3566 N N   . PHE C 3 61  ? 88.423  99.321  93.362  1.00 35.95  ? 61  PHE E N   1 
ATOM 3567 C CA  . PHE C 3 61  ? 89.403  100.025 94.190  1.00 28.47  ? 61  PHE E CA  1 
ATOM 3568 C C   . PHE C 3 61  ? 89.053  99.864  95.660  1.00 27.80  ? 61  PHE E C   1 
ATOM 3569 O O   . PHE C 3 61  ? 88.836  100.830 96.393  1.00 31.02  ? 61  PHE E O   1 
ATOM 3570 C CB  . PHE C 3 61  ? 89.503  101.504 93.823  1.00 31.06  ? 61  PHE E CB  1 
ATOM 3571 C CG  . PHE C 3 61  ? 90.129  101.750 92.480  1.00 29.53  ? 61  PHE E CG  1 
ATOM 3572 C CD1 . PHE C 3 61  ? 91.504  101.726 92.334  1.00 21.69  ? 61  PHE E CD1 1 
ATOM 3573 C CD2 . PHE C 3 61  ? 89.347  102.000 91.366  1.00 26.12  ? 61  PHE E CD2 1 
ATOM 3574 C CE1 . PHE C 3 61  ? 92.084  101.943 91.109  1.00 19.15  ? 61  PHE E CE1 1 
ATOM 3575 C CE2 . PHE C 3 61  ? 89.927  102.221 90.135  1.00 20.80  ? 61  PHE E CE2 1 
ATOM 3576 C CZ  . PHE C 3 61  ? 91.296  102.193 90.008  1.00 24.49  ? 61  PHE E CZ  1 
ATOM 3577 N N   . ARG C 3 62  ? 88.978  98.618  96.104  1.00 49.31  ? 62  ARG E N   1 
ATOM 3578 C CA  . ARG C 3 62  ? 88.627  98.314  97.482  1.00 54.39  ? 62  ARG E CA  1 
ATOM 3579 C C   . ARG C 3 62  ? 89.718  98.764  98.451  1.00 56.17  ? 62  ARG E C   1 
ATOM 3580 O O   . ARG C 3 62  ? 89.443  99.460  99.430  1.00 56.33  ? 62  ARG E O   1 
ATOM 3581 C CB  . ARG C 3 62  ? 88.361  96.817  97.630  1.00 53.09  ? 62  ARG E CB  1 
ATOM 3582 C CG  . ARG C 3 62  ? 87.116  96.354  96.888  1.00 54.88  ? 62  ARG E CG  1 
ATOM 3583 C CD  . ARG C 3 62  ? 87.151  94.866  96.567  1.00 56.02  ? 62  ARG E CD  1 
ATOM 3584 N NE  . ARG C 3 62  ? 86.153  94.501  95.570  1.00 56.41  ? 62  ARG E NE  1 
ATOM 3585 C CZ  . ARG C 3 62  ? 86.420  94.211  94.303  1.00 55.15  ? 62  ARG E CZ  1 
ATOM 3586 N NH1 . ARG C 3 62  ? 87.660  94.188  93.844  1.00 54.37  ? 62  ARG E NH1 1 
ATOM 3587 N NH2 . ARG C 3 62  ? 85.413  93.948  93.473  1.00 54.08  ? 62  ARG E NH2 1 
ATOM 3588 N N   . VAL D 4 40  ? 116.631 88.291  67.559  1.00 47.62  ? 40  VAL F N   1 
ATOM 3589 C CA  . VAL D 4 40  ? 116.848 87.531  68.821  1.00 51.34  ? 40  VAL F CA  1 
ATOM 3590 C C   . VAL D 4 40  ? 117.297 86.111  68.496  1.00 52.07  ? 40  VAL F C   1 
ATOM 3591 O O   . VAL D 4 40  ? 116.688 85.435  67.667  1.00 46.99  ? 40  VAL F O   1 
ATOM 3592 C CB  . VAL D 4 40  ? 115.574 87.524  69.699  1.00 47.59  ? 40  VAL F CB  1 
ATOM 3593 C CG1 . VAL D 4 40  ? 115.329 88.901  70.287  1.00 46.59  ? 40  VAL F CG1 1 
ATOM 3594 C CG2 . VAL D 4 40  ? 114.364 87.068  68.901  1.00 47.77  ? 40  VAL F CG2 1 
ATOM 3595 N N   . GLN D 4 41  ? 118.374 85.667  69.144  1.00 54.33  ? 41  GLN F N   1 
ATOM 3596 C CA  . GLN D 4 41  ? 118.906 84.325  68.959  1.00 50.06  ? 41  GLN F CA  1 
ATOM 3597 C C   . GLN D 4 41  ? 119.086 83.646  70.308  1.00 53.74  ? 41  GLN F C   1 
ATOM 3598 O O   . GLN D 4 41  ? 119.554 84.265  71.268  1.00 58.46  ? 41  GLN F O   1 
ATOM 3599 C CB  . GLN D 4 41  ? 120.254 84.341  68.217  1.00 52.40  ? 41  GLN F CB  1 
ATOM 3600 C CG  . GLN D 4 41  ? 120.188 84.820  66.770  1.00 54.42  ? 41  GLN F CG  1 
ATOM 3601 C CD  . GLN D 4 41  ? 120.581 86.279  66.600  1.00 57.82  ? 41  GLN F CD  1 
ATOM 3602 O OE1 . GLN D 4 41  ? 121.258 86.860  67.449  1.00 56.72  ? 41  GLN F OE1 1 
ATOM 3603 N NE2 . GLN D 4 41  ? 120.161 86.876  65.491  1.00 56.13  ? 41  GLN F NE2 1 
ATOM 3604 N N   . LEU D 4 42  ? 118.704 82.372  70.373  1.00 52.77  ? 42  LEU F N   1 
ATOM 3605 C CA  . LEU D 4 42  ? 118.995 81.501  71.507  1.00 52.92  ? 42  LEU F CA  1 
ATOM 3606 C C   . LEU D 4 42  ? 119.614 80.225  70.960  1.00 55.56  ? 42  LEU F C   1 
ATOM 3607 O O   . LEU D 4 42  ? 118.979 79.515  70.174  1.00 54.24  ? 42  LEU F O   1 
ATOM 3608 C CB  . LEU D 4 42  ? 117.731 81.183  72.314  1.00 53.41  ? 42  LEU F CB  1 
ATOM 3609 C CG  . LEU D 4 42  ? 117.218 82.242  73.294  1.00 53.43  ? 42  LEU F CG  1 
ATOM 3610 C CD1 . LEU D 4 42  ? 115.859 81.843  73.838  1.00 45.94  ? 42  LEU F CD1 1 
ATOM 3611 C CD2 . LEU D 4 42  ? 118.198 82.461  74.434  1.00 56.07  ? 42  LEU F CD2 1 
ATOM 3612 N N   . VAL D 4 43  ? 120.851 79.940  71.363  1.00 61.35  ? 43  VAL F N   1 
ATOM 3613 C CA  . VAL D 4 43  ? 121.586 78.776  70.876  1.00 60.06  ? 43  VAL F CA  1 
ATOM 3614 C C   . VAL D 4 43  ? 122.268 78.101  72.057  1.00 60.64  ? 43  VAL F C   1 
ATOM 3615 O O   . VAL D 4 43  ? 122.919 78.767  72.869  1.00 59.24  ? 43  VAL F O   1 
ATOM 3616 C CB  . VAL D 4 43  ? 122.621 79.164  69.801  1.00 60.97  ? 43  VAL F CB  1 
ATOM 3617 C CG1 . VAL D 4 43  ? 123.393 77.942  69.336  1.00 63.03  ? 43  VAL F CG1 1 
ATOM 3618 C CG2 . VAL D 4 43  ? 121.936 79.843  68.624  1.00 61.79  ? 43  VAL F CG2 1 
ATOM 3619 N N   . GLU D 4 44  ? 122.133 76.780  72.142  1.00 69.24  ? 44  GLU F N   1 
ATOM 3620 C CA  . GLU D 4 44  ? 122.686 75.987  73.230  1.00 67.83  ? 44  GLU F CA  1 
ATOM 3621 C C   . GLU D 4 44  ? 123.909 75.210  72.758  1.00 69.09  ? 44  GLU F C   1 
ATOM 3622 O O   . GLU D 4 44  ? 124.055 74.887  71.576  1.00 68.91  ? 44  GLU F O   1 
ATOM 3623 C CB  . GLU D 4 44  ? 121.644 75.010  73.787  1.00 64.81  ? 44  GLU F CB  1 
ATOM 3624 C CG  . GLU D 4 44  ? 120.465 75.668  74.476  1.00 67.64  ? 44  GLU F CG  1 
ATOM 3625 C CD  . GLU D 4 44  ? 119.425 76.180  73.503  1.00 67.65  ? 44  GLU F CD  1 
ATOM 3626 O OE1 . GLU D 4 44  ? 119.775 76.418  72.330  1.00 68.70  ? 44  GLU F OE1 1 
ATOM 3627 O OE2 . GLU D 4 44  ? 118.257 76.342  73.908  1.00 63.56  ? 44  GLU F OE2 1 
ATOM 3628 N N   . SER D 4 45  ? 124.787 74.905  73.713  1.00 80.14  ? 45  SER F N   1 
ATOM 3629 C CA  . SER D 4 45  ? 126.004 74.152  73.439  1.00 78.52  ? 45  SER F CA  1 
ATOM 3630 C C   . SER D 4 45  ? 126.086 72.936  74.353  1.00 79.19  ? 45  SER F C   1 
ATOM 3631 O O   . SER D 4 45  ? 125.126 72.622  75.063  1.00 79.63  ? 45  SER F O   1 
ATOM 3632 C CB  . SER D 4 45  ? 127.237 75.040  73.617  1.00 78.23  ? 45  SER F CB  1 
ATOM 3633 O OG  . SER D 4 45  ? 127.365 75.473  74.959  1.00 79.04  ? 45  SER F OG  1 
ATOM 3634 N N   . GLY D 4 46  ? 127.223 72.248  74.343  1.00 79.65  ? 46  GLY F N   1 
ATOM 3635 C CA  . GLY D 4 46  ? 127.380 71.066  75.164  1.00 79.94  ? 46  GLY F CA  1 
ATOM 3636 C C   . GLY D 4 46  ? 126.628 69.876  74.594  1.00 81.65  ? 46  GLY F C   1 
ATOM 3637 O O   . GLY D 4 46  ? 126.295 69.814  73.406  1.00 82.86  ? 46  GLY F O   1 
ATOM 3638 N N   . GLY D 4 47  ? 126.362 68.911  75.470  1.00 80.88  ? 47  GLY F N   1 
ATOM 3639 C CA  . GLY D 4 47  ? 125.648 67.715  75.077  1.00 81.63  ? 47  GLY F CA  1 
ATOM 3640 C C   . GLY D 4 47  ? 126.558 66.688  74.435  1.00 82.38  ? 47  GLY F C   1 
ATOM 3641 O O   . GLY D 4 47  ? 127.763 66.882  74.264  1.00 82.66  ? 47  GLY F O   1 
ATOM 3642 N N   . GLY D 4 48  ? 125.951 65.562  74.067  1.00 88.22  ? 48  GLY F N   1 
ATOM 3643 C CA  . GLY D 4 48  ? 126.678 64.471  73.447  1.00 88.16  ? 48  GLY F CA  1 
ATOM 3644 C C   . GLY D 4 48  ? 126.448 63.145  74.139  1.00 89.07  ? 48  GLY F C   1 
ATOM 3645 O O   . GLY D 4 48  ? 125.313 62.810  74.492  1.00 89.04  ? 48  GLY F O   1 
ATOM 3646 N N   . LEU D 4 49  ? 127.519 62.381  74.336  1.00 91.14  ? 49  LEU F N   1 
ATOM 3647 C CA  . LEU D 4 49  ? 127.460 61.075  74.979  1.00 91.98  ? 49  LEU F CA  1 
ATOM 3648 C C   . LEU D 4 49  ? 128.216 61.126  76.299  1.00 91.11  ? 49  LEU F C   1 
ATOM 3649 O O   . LEU D 4 49  ? 129.349 61.615  76.352  1.00 90.52  ? 49  LEU F O   1 
ATOM 3650 C CB  . LEU D 4 49  ? 128.047 59.996  74.067  1.00 92.30  ? 49  LEU F CB  1 
ATOM 3651 C CG  . LEU D 4 49  ? 127.943 58.553  74.565  1.00 92.43  ? 49  LEU F CG  1 
ATOM 3652 C CD1 . LEU D 4 49  ? 126.490 58.128  74.718  1.00 90.81  ? 49  LEU F CD1 1 
ATOM 3653 C CD2 . LEU D 4 49  ? 128.682 57.617  73.622  1.00 91.32  ? 49  LEU F CD2 1 
ATOM 3654 N N   . VAL D 4 50  ? 127.584 60.627  77.359  1.00 92.53  ? 50  VAL F N   1 
ATOM 3655 C CA  . VAL D 4 50  ? 128.148 60.650  78.703  1.00 93.37  ? 50  VAL F CA  1 
ATOM 3656 C C   . VAL D 4 50  ? 127.786 59.349  79.404  1.00 92.62  ? 50  VAL F C   1 
ATOM 3657 O O   . VAL D 4 50  ? 126.662 58.853  79.272  1.00 93.26  ? 50  VAL F O   1 
ATOM 3658 C CB  . VAL D 4 50  ? 127.640 61.867  79.507  1.00 94.02  ? 50  VAL F CB  1 
ATOM 3659 C CG1 . VAL D 4 50  ? 126.117 61.879  79.560  1.00 93.30  ? 50  VAL F CG1 1 
ATOM 3660 C CG2 . VAL D 4 50  ? 128.232 61.871  80.910  1.00 93.83  ? 50  VAL F CG2 1 
ATOM 3661 N N   . GLN D 4 51  ? 128.739 58.796  80.150  1.00 95.01  ? 51  GLN F N   1 
ATOM 3662 C CA  . GLN D 4 51  ? 128.484 57.566  80.881  1.00 96.12  ? 51  GLN F CA  1 
ATOM 3663 C C   . GLN D 4 51  ? 127.596 57.846  82.094  1.00 95.49  ? 51  GLN F C   1 
ATOM 3664 O O   . GLN D 4 51  ? 127.559 58.971  82.600  1.00 93.90  ? 51  GLN F O   1 
ATOM 3665 C CB  . GLN D 4 51  ? 129.793 56.925  81.334  1.00 96.16  ? 51  GLN F CB  1 
ATOM 3666 C CG  . GLN D 4 51  ? 130.520 56.164  80.236  1.00 96.30  ? 51  GLN F CG  1 
ATOM 3667 C CD  . GLN D 4 51  ? 131.034 57.074  79.140  1.00 96.27  ? 51  GLN F CD  1 
ATOM 3668 O OE1 . GLN D 4 51  ? 131.332 58.243  79.378  1.00 96.26  ? 51  GLN F OE1 1 
ATOM 3669 N NE2 . GLN D 4 51  ? 131.136 56.541  77.928  1.00 95.29  ? 51  GLN F NE2 1 
ATOM 3670 N N   . PRO D 4 52  ? 126.867 56.840  82.580  1.00 95.57  ? 52  PRO F N   1 
ATOM 3671 C CA  . PRO D 4 52  ? 126.009 57.062  83.749  1.00 96.14  ? 52  PRO F CA  1 
ATOM 3672 C C   . PRO D 4 52  ? 126.823 57.489  84.961  1.00 95.10  ? 52  PRO F C   1 
ATOM 3673 O O   . PRO D 4 52  ? 127.953 57.041  85.164  1.00 93.83  ? 52  PRO F O   1 
ATOM 3674 C CB  . PRO D 4 52  ? 125.340 55.698  83.967  1.00 94.80  ? 52  PRO F CB  1 
ATOM 3675 C CG  . PRO D 4 52  ? 125.494 54.974  82.679  1.00 95.23  ? 52  PRO F CG  1 
ATOM 3676 C CD  . PRO D 4 52  ? 126.782 55.451  82.100  1.00 95.11  ? 52  PRO F CD  1 
ATOM 3677 N N   . GLY D 4 53  ? 126.234 58.368  85.767  1.00 91.08  ? 53  GLY F N   1 
ATOM 3678 C CA  . GLY D 4 53  ? 126.889 58.871  86.954  1.00 89.87  ? 53  GLY F CA  1 
ATOM 3679 C C   . GLY D 4 53  ? 127.892 59.975  86.713  1.00 90.74  ? 53  GLY F C   1 
ATOM 3680 O O   . GLY D 4 53  ? 128.500 60.456  87.676  1.00 89.70  ? 53  GLY F O   1 
ATOM 3681 N N   . GLY D 4 54  ? 128.083 60.398  85.463  1.00 89.50  ? 54  GLY F N   1 
ATOM 3682 C CA  . GLY D 4 54  ? 129.052 61.428  85.136  1.00 88.79  ? 54  GLY F CA  1 
ATOM 3683 C C   . GLY D 4 54  ? 128.371 62.771  84.950  1.00 87.88  ? 54  GLY F C   1 
ATOM 3684 O O   . GLY D 4 54  ? 127.411 62.894  84.187  1.00 89.76  ? 54  GLY F O   1 
ATOM 3685 N N   . SER D 4 55  ? 128.885 63.774  85.654  1.00 81.51  ? 55  SER F N   1 
ATOM 3686 C CA  . SER D 4 55  ? 128.303 65.106  85.591  1.00 82.01  ? 55  SER F CA  1 
ATOM 3687 C C   . SER D 4 55  ? 128.532 65.731  84.220  1.00 82.71  ? 55  SER F C   1 
ATOM 3688 O O   . SER D 4 55  ? 129.559 65.512  83.572  1.00 82.30  ? 55  SER F O   1 
ATOM 3689 C CB  . SER D 4 55  ? 128.899 66.000  86.676  1.00 80.70  ? 55  SER F CB  1 
ATOM 3690 O OG  . SER D 4 55  ? 130.275 66.234  86.443  1.00 80.80  ? 55  SER F OG  1 
ATOM 3691 N N   . ARG D 4 56  ? 127.551 66.515  83.778  1.00 80.47  ? 56  ARG F N   1 
ATOM 3692 C CA  . ARG D 4 56  ? 127.640 67.246  82.524  1.00 79.59  ? 56  ARG F CA  1 
ATOM 3693 C C   . ARG D 4 56  ? 127.094 68.648  82.741  1.00 78.29  ? 56  ARG F C   1 
ATOM 3694 O O   . ARG D 4 56  ? 126.344 68.903  83.686  1.00 79.63  ? 56  ARG F O   1 
ATOM 3695 C CB  . ARG D 4 56  ? 126.875 66.534  81.398  1.00 80.22  ? 56  ARG F CB  1 
ATOM 3696 C CG  . ARG D 4 56  ? 127.213 67.014  79.989  1.00 79.89  ? 56  ARG F CG  1 
ATOM 3697 C CD  . ARG D 4 56  ? 128.701 66.906  79.694  1.00 81.58  ? 56  ARG F CD  1 
ATOM 3698 N NE  . ARG D 4 56  ? 128.993 66.971  78.266  1.00 82.81  ? 56  ARG F NE  1 
ATOM 3699 C CZ  . ARG D 4 56  ? 129.183 65.919  77.479  1.00 81.84  ? 56  ARG F CZ  1 
ATOM 3700 N NH1 . ARG D 4 56  ? 129.112 64.681  77.941  1.00 81.15  ? 56  ARG F NH1 1 
ATOM 3701 N NH2 . ARG D 4 56  ? 129.454 66.115  76.191  1.00 80.15  ? 56  ARG F NH2 1 
ATOM 3702 N N   . LYS D 4 57  ? 127.498 69.567  81.867  1.00 70.53  ? 57  LYS F N   1 
ATOM 3703 C CA  . LYS D 4 57  ? 127.064 70.955  81.939  1.00 70.11  ? 57  LYS F CA  1 
ATOM 3704 C C   . LYS D 4 57  ? 126.601 71.414  80.566  1.00 71.00  ? 57  LYS F C   1 
ATOM 3705 O O   . LYS D 4 57  ? 127.317 71.240  79.576  1.00 72.49  ? 57  LYS F O   1 
ATOM 3706 C CB  . LYS D 4 57  ? 128.189 71.859  82.445  1.00 67.87  ? 57  LYS F CB  1 
ATOM 3707 C CG  . LYS D 4 57  ? 127.802 73.320  82.532  1.00 68.81  ? 57  LYS F CG  1 
ATOM 3708 C CD  . LYS D 4 57  ? 128.719 74.089  83.458  1.00 69.31  ? 57  LYS F CD  1 
ATOM 3709 C CE  . LYS D 4 57  ? 128.205 75.495  83.692  1.00 68.63  ? 57  LYS F CE  1 
ATOM 3710 N NZ  . LYS D 4 57  ? 128.960 76.198  84.763  1.00 69.27  ? 57  LYS F NZ  1 
ATOM 3711 N N   . LEU D 4 58  ? 125.406 71.997  80.513  1.00 66.14  ? 58  LEU F N   1 
ATOM 3712 C CA  . LEU D 4 58  ? 124.857 72.577  79.297  1.00 67.69  ? 58  LEU F CA  1 
ATOM 3713 C C   . LEU D 4 58  ? 124.754 74.086  79.463  1.00 67.69  ? 58  LEU F C   1 
ATOM 3714 O O   . LEU D 4 58  ? 124.457 74.579  80.556  1.00 65.57  ? 58  LEU F O   1 
ATOM 3715 C CB  . LEU D 4 58  ? 123.480 71.994  78.977  1.00 67.08  ? 58  LEU F CB  1 
ATOM 3716 C CG  . LEU D 4 58  ? 123.374 70.470  78.907  1.00 67.35  ? 58  LEU F CG  1 
ATOM 3717 C CD1 . LEU D 4 58  ? 121.970 70.072  78.489  1.00 68.39  ? 58  LEU F CD1 1 
ATOM 3718 C CD2 . LEU D 4 58  ? 124.406 69.884  77.957  1.00 66.70  ? 58  LEU F CD2 1 
ATOM 3719 N N   . SER D 4 59  ? 125.004 74.815  78.379  1.00 64.70  ? 59  SER F N   1 
ATOM 3720 C CA  . SER D 4 59  ? 125.012 76.268  78.402  1.00 65.41  ? 59  SER F CA  1 
ATOM 3721 C C   . SER D 4 59  ? 124.243 76.808  77.205  1.00 68.04  ? 59  SER F C   1 
ATOM 3722 O O   . SER D 4 59  ? 124.115 76.141  76.176  1.00 66.32  ? 59  SER F O   1 
ATOM 3723 C CB  . SER D 4 59  ? 126.441 76.815  78.390  1.00 66.10  ? 59  SER F CB  1 
ATOM 3724 O OG  . SER D 4 59  ? 126.463 78.188  78.730  1.00 65.43  ? 59  SER F OG  1 
ATOM 3725 N N   . CYS D 4 60  ? 123.726 78.026  77.359  1.00 67.72  ? 60  CYS F N   1 
ATOM 3726 C CA  . CYS D 4 60  ? 122.973 78.701  76.312  1.00 67.66  ? 60  CYS F CA  1 
ATOM 3727 C C   . CYS D 4 60  ? 123.407 80.155  76.245  1.00 66.95  ? 60  CYS F C   1 
ATOM 3728 O O   . CYS D 4 60  ? 123.588 80.802  77.279  1.00 63.16  ? 60  CYS F O   1 
ATOM 3729 C CB  . CYS D 4 60  ? 121.464 78.623  76.565  1.00 67.59  ? 60  CYS F CB  1 
ATOM 3730 S SG  . CYS D 4 60  ? 120.455 79.259  75.207  1.00 74.67  ? 60  CYS F SG  1 
ATOM 3731 N N   . SER D 4 61  ? 123.567 80.665  75.027  1.00 65.07  ? 61  SER F N   1 
ATOM 3732 C CA  . SER D 4 61  ? 123.956 82.047  74.788  1.00 64.31  ? 61  SER F CA  1 
ATOM 3733 C C   . SER D 4 61  ? 122.794 82.804  74.164  1.00 64.45  ? 61  SER F C   1 
ATOM 3734 O O   . SER D 4 61  ? 122.113 82.289  73.272  1.00 62.94  ? 61  SER F O   1 
ATOM 3735 C CB  . SER D 4 61  ? 125.179 82.123  73.873  1.00 62.98  ? 61  SER F CB  1 
ATOM 3736 O OG  . SER D 4 61  ? 125.535 83.468  73.612  1.00 64.14  ? 61  SER F OG  1 
ATOM 3737 N N   . ALA D 4 62  ? 122.573 84.029  74.636  1.00 63.00  ? 62  ALA F N   1 
ATOM 3738 C CA  . ALA D 4 62  ? 121.463 84.861  74.197  1.00 62.43  ? 62  ALA F CA  1 
ATOM 3739 C C   . ALA D 4 62  ? 121.990 86.179  73.648  1.00 63.43  ? 62  ALA F C   1 
ATOM 3740 O O   . ALA D 4 62  ? 122.911 86.775  74.215  1.00 65.49  ? 62  ALA F O   1 
ATOM 3741 C CB  . ALA D 4 62  ? 120.487 85.127  75.346  1.00 59.42  ? 62  ALA F CB  1 
ATOM 3742 N N   . SER D 4 63  ? 121.399 86.631  72.544  1.00 58.45  ? 63  SER F N   1 
ATOM 3743 C CA  . SER D 4 63  ? 121.785 87.889  71.925  1.00 58.10  ? 63  SER F CA  1 
ATOM 3744 C C   . SER D 4 63  ? 120.593 88.452  71.167  1.00 57.82  ? 63  SER F C   1 
ATOM 3745 O O   . SER D 4 63  ? 119.800 87.699  70.597  1.00 55.42  ? 63  SER F O   1 
ATOM 3746 C CB  . SER D 4 63  ? 122.977 87.707  70.979  1.00 55.44  ? 63  SER F CB  1 
ATOM 3747 O OG  . SER D 4 63  ? 122.673 86.793  69.941  1.00 58.39  ? 63  SER F OG  1 
ATOM 3748 N N   . GLY D 4 64  ? 120.476 89.776  71.164  1.00 49.39  ? 64  GLY F N   1 
ATOM 3749 C CA  . GLY D 4 64  ? 119.407 90.453  70.462  1.00 48.49  ? 64  GLY F CA  1 
ATOM 3750 C C   . GLY D 4 64  ? 118.272 90.964  71.321  1.00 50.52  ? 64  GLY F C   1 
ATOM 3751 O O   . GLY D 4 64  ? 117.263 91.414  70.770  1.00 51.38  ? 64  GLY F O   1 
ATOM 3752 N N   . PHE D 4 65  ? 118.393 90.901  72.644  1.00 41.57  ? 65  PHE F N   1 
ATOM 3753 C CA  . PHE D 4 65  ? 117.362 91.427  73.528  1.00 40.39  ? 65  PHE F CA  1 
ATOM 3754 C C   . PHE D 4 65  ? 117.973 91.667  74.899  1.00 44.68  ? 65  PHE F C   1 
ATOM 3755 O O   . PHE D 4 65  ? 119.090 91.233  75.189  1.00 43.68  ? 65  PHE F O   1 
ATOM 3756 C CB  . PHE D 4 65  ? 116.160 90.481  73.615  1.00 40.42  ? 65  PHE F CB  1 
ATOM 3757 C CG  . PHE D 4 65  ? 116.471 89.149  74.234  1.00 41.99  ? 65  PHE F CG  1 
ATOM 3758 C CD1 . PHE D 4 65  ? 117.088 88.153  73.497  1.00 44.09  ? 65  PHE F CD1 1 
ATOM 3759 C CD2 . PHE D 4 65  ? 116.130 88.887  75.551  1.00 42.07  ? 65  PHE F CD2 1 
ATOM 3760 C CE1 . PHE D 4 65  ? 117.368 86.926  74.064  1.00 43.50  ? 65  PHE F CE1 1 
ATOM 3761 C CE2 . PHE D 4 65  ? 116.407 87.661  76.122  1.00 39.98  ? 65  PHE F CE2 1 
ATOM 3762 C CZ  . PHE D 4 65  ? 117.025 86.682  75.379  1.00 40.64  ? 65  PHE F CZ  1 
ATOM 3763 N N   . ALA D 4 66  ? 117.228 92.382  75.738  1.00 38.16  ? 66  ALA F N   1 
ATOM 3764 C CA  . ALA D 4 66  ? 117.642 92.639  77.115  1.00 41.40  ? 66  ALA F CA  1 
ATOM 3765 C C   . ALA D 4 66  ? 117.555 91.337  77.898  1.00 44.08  ? 66  ALA F C   1 
ATOM 3766 O O   . ALA D 4 66  ? 116.470 90.896  78.278  1.00 47.29  ? 66  ALA F O   1 
ATOM 3767 C CB  . ALA D 4 66  ? 116.768 93.719  77.740  1.00 39.18  ? 66  ALA F CB  1 
ATOM 3768 N N   . PHE D 4 67  ? 118.708 90.713  78.145  1.00 45.17  ? 67  PHE F N   1 
ATOM 3769 C CA  . PHE D 4 67  ? 118.719 89.391  78.763  1.00 45.88  ? 67  PHE F CA  1 
ATOM 3770 C C   . PHE D 4 67  ? 118.244 89.443  80.210  1.00 41.77  ? 67  PHE F C   1 
ATOM 3771 O O   . PHE D 4 67  ? 117.540 88.538  80.670  1.00 42.26  ? 67  PHE F O   1 
ATOM 3772 C CB  . PHE D 4 67  ? 120.125 88.796  78.677  1.00 44.80  ? 67  PHE F CB  1 
ATOM 3773 C CG  . PHE D 4 67  ? 120.241 87.419  79.259  1.00 46.68  ? 67  PHE F CG  1 
ATOM 3774 C CD1 . PHE D 4 67  ? 119.809 86.315  78.549  1.00 48.40  ? 67  PHE F CD1 1 
ATOM 3775 C CD2 . PHE D 4 67  ? 120.793 87.227  80.515  1.00 46.70  ? 67  PHE F CD2 1 
ATOM 3776 C CE1 . PHE D 4 67  ? 119.917 85.048  79.082  1.00 49.74  ? 67  PHE F CE1 1 
ATOM 3777 C CE2 . PHE D 4 67  ? 120.901 85.960  81.052  1.00 43.24  ? 67  PHE F CE2 1 
ATOM 3778 C CZ  . PHE D 4 67  ? 120.463 84.872  80.334  1.00 43.29  ? 67  PHE F CZ  1 
ATOM 3779 N N   . SER D 4 68  ? 118.615 90.493  80.941  1.00 38.24  ? 68  SER F N   1 
ATOM 3780 C CA  . SER D 4 68  ? 118.371 90.541  82.377  1.00 40.45  ? 68  SER F CA  1 
ATOM 3781 C C   . SER D 4 68  ? 116.915 90.799  82.736  1.00 44.45  ? 68  SER F C   1 
ATOM 3782 O O   . SER D 4 68  ? 116.556 90.655  83.909  1.00 47.61  ? 68  SER F O   1 
ATOM 3783 C CB  . SER D 4 68  ? 119.247 91.621  83.011  1.00 43.69  ? 68  SER F CB  1 
ATOM 3784 O OG  . SER D 4 68  ? 119.033 92.873  82.386  1.00 44.36  ? 68  SER F OG  1 
ATOM 3785 N N   . SER D 4 69  ? 116.076 91.175  81.776  1.00 40.53  ? 69  SER F N   1 
ATOM 3786 C CA  . SER D 4 69  ? 114.679 91.491  82.036  1.00 27.15  ? 69  SER F CA  1 
ATOM 3787 C C   . SER D 4 69  ? 113.747 90.332  81.714  1.00 31.12  ? 69  SER F C   1 
ATOM 3788 O O   . SER D 4 69  ? 112.526 90.515  81.715  1.00 38.43  ? 69  SER F O   1 
ATOM 3789 C CB  . SER D 4 69  ? 114.271 92.725  81.235  1.00 36.34  ? 69  SER F CB  1 
ATOM 3790 O OG  . SER D 4 69  ? 115.031 93.854  81.623  1.00 39.36  ? 69  SER F OG  1 
ATOM 3791 N N   . PHE D 4 70  ? 114.291 89.150  81.442  1.00 27.65  ? 70  PHE F N   1 
ATOM 3792 C CA  . PHE D 4 70  ? 113.513 87.981  81.067  1.00 25.14  ? 70  PHE F CA  1 
ATOM 3793 C C   . PHE D 4 70  ? 113.802 86.833  82.024  1.00 30.17  ? 70  PHE F C   1 
ATOM 3794 O O   . PHE D 4 70  ? 114.950 86.613  82.416  1.00 42.44  ? 70  PHE F O   1 
ATOM 3795 C CB  . PHE D 4 70  ? 113.839 87.543  79.635  1.00 25.15  ? 70  PHE F CB  1 
ATOM 3796 C CG  . PHE D 4 70  ? 113.195 88.384  78.579  1.00 25.44  ? 70  PHE F CG  1 
ATOM 3797 C CD1 . PHE D 4 70  ? 113.735 89.605  78.221  1.00 24.54  ? 70  PHE F CD1 1 
ATOM 3798 C CD2 . PHE D 4 70  ? 112.054 87.949  77.934  1.00 27.34  ? 70  PHE F CD2 1 
ATOM 3799 C CE1 . PHE D 4 70  ? 113.145 90.379  77.248  1.00 27.81  ? 70  PHE F CE1 1 
ATOM 3800 C CE2 . PHE D 4 70  ? 111.460 88.718  76.960  1.00 30.61  ? 70  PHE F CE2 1 
ATOM 3801 C CZ  . PHE D 4 70  ? 112.006 89.934  76.616  1.00 31.58  ? 70  PHE F CZ  1 
ATOM 3802 N N   . GLY D 4 71  ? 112.754 86.108  82.404  1.00 22.26  ? 71  GLY F N   1 
ATOM 3803 C CA  . GLY D 4 71  ? 112.941 84.831  83.057  1.00 21.26  ? 71  GLY F CA  1 
ATOM 3804 C C   . GLY D 4 71  ? 113.223 83.739  82.043  1.00 25.48  ? 71  GLY F C   1 
ATOM 3805 O O   . GLY D 4 71  ? 112.780 83.796  80.899  1.00 27.70  ? 71  GLY F O   1 
ATOM 3806 N N   . MET D 4 72  ? 113.972 82.727  82.474  1.00 33.76  ? 72  MET F N   1 
ATOM 3807 C CA  . MET D 4 72  ? 114.432 81.664  81.593  1.00 32.49  ? 72  MET F CA  1 
ATOM 3808 C C   . MET D 4 72  ? 113.961 80.310  82.106  1.00 35.50  ? 72  MET F C   1 
ATOM 3809 O O   . MET D 4 72  ? 113.830 80.095  83.313  1.00 39.59  ? 72  MET F O   1 
ATOM 3810 C CB  . MET D 4 72  ? 115.959 81.665  81.474  1.00 26.43  ? 72  MET F CB  1 
ATOM 3811 C CG  . MET D 4 72  ? 116.569 83.025  81.163  1.00 34.76  ? 72  MET F CG  1 
ATOM 3812 S SD  . MET D 4 72  ? 116.132 83.671  79.539  1.00 44.18  ? 72  MET F SD  1 
ATOM 3813 C CE  . MET D 4 72  ? 117.005 82.538  78.467  1.00 30.42  ? 72  MET F CE  1 
ATOM 3814 N N   . HIS D 4 73  ? 113.710 79.396  81.171  1.00 37.13  ? 73  HIS F N   1 
ATOM 3815 C CA  . HIS D 4 73  ? 113.247 78.051  81.477  1.00 30.86  ? 73  HIS F CA  1 
ATOM 3816 C C   . HIS D 4 73  ? 114.117 77.029  80.762  1.00 32.82  ? 73  HIS F C   1 
ATOM 3817 O O   . HIS D 4 73  ? 114.822 77.342  79.801  1.00 32.78  ? 73  HIS F O   1 
ATOM 3818 C CB  . HIS D 4 73  ? 111.787 77.836  81.054  1.00 31.30  ? 73  HIS F CB  1 
ATOM 3819 C CG  . HIS D 4 73  ? 110.801 78.652  81.825  1.00 26.58  ? 73  HIS F CG  1 
ATOM 3820 N ND1 . HIS D 4 73  ? 109.921 78.096  82.727  1.00 31.49  ? 73  HIS F ND1 1 
ATOM 3821 C CD2 . HIS D 4 73  ? 110.545 79.980  81.822  1.00 31.35  ? 73  HIS F CD2 1 
ATOM 3822 C CE1 . HIS D 4 73  ? 109.168 79.046  83.248  1.00 33.01  ? 73  HIS F CE1 1 
ATOM 3823 N NE2 . HIS D 4 73  ? 109.528 80.200  82.718  1.00 38.46  ? 73  HIS F NE2 1 
ATOM 3824 N N   . TRP D 4 74  ? 114.054 75.794  81.251  1.00 33.05  ? 74  TRP F N   1 
ATOM 3825 C CA  . TRP D 4 74  ? 114.602 74.633  80.566  1.00 33.25  ? 74  TRP F CA  1 
ATOM 3826 C C   . TRP D 4 74  ? 113.469 73.649  80.326  1.00 33.62  ? 74  TRP F C   1 
ATOM 3827 O O   . TRP D 4 74  ? 112.651 73.412  81.219  1.00 35.26  ? 74  TRP F O   1 
ATOM 3828 C CB  . TRP D 4 74  ? 115.722 73.970  81.375  1.00 35.79  ? 74  TRP F CB  1 
ATOM 3829 C CG  . TRP D 4 74  ? 117.028 74.687  81.283  1.00 34.67  ? 74  TRP F CG  1 
ATOM 3830 C CD1 . TRP D 4 74  ? 117.576 75.512  82.216  1.00 31.56  ? 74  TRP F CD1 1 
ATOM 3831 C CD2 . TRP D 4 74  ? 117.953 74.649  80.190  1.00 35.70  ? 74  TRP F CD2 1 
ATOM 3832 N NE1 . TRP D 4 74  ? 118.782 75.991  81.773  1.00 36.46  ? 74  TRP F NE1 1 
ATOM 3833 C CE2 . TRP D 4 74  ? 119.036 75.475  80.531  1.00 34.81  ? 74  TRP F CE2 1 
ATOM 3834 C CE3 . TRP D 4 74  ? 117.969 73.997  78.955  1.00 40.92  ? 74  TRP F CE3 1 
ATOM 3835 C CZ2 . TRP D 4 74  ? 120.124 75.666  79.685  1.00 36.52  ? 74  TRP F CZ2 1 
ATOM 3836 C CZ3 . TRP D 4 74  ? 119.048 74.188  78.118  1.00 40.50  ? 74  TRP F CZ3 1 
ATOM 3837 C CH2 . TRP D 4 74  ? 120.110 75.014  78.486  1.00 38.69  ? 74  TRP F CH2 1 
ATOM 3838 N N   . VAL D 4 75  ? 113.405 73.105  79.116  1.00 31.79  ? 75  VAL F N   1 
ATOM 3839 C CA  . VAL D 4 75  ? 112.386 72.131  78.744  1.00 39.28  ? 75  VAL F CA  1 
ATOM 3840 C C   . VAL D 4 75  ? 113.053 71.059  77.897  1.00 34.99  ? 75  VAL F C   1 
ATOM 3841 O O   . VAL D 4 75  ? 113.857 71.374  77.014  1.00 39.53  ? 75  VAL F O   1 
ATOM 3842 C CB  . VAL D 4 75  ? 111.214 72.788  77.983  1.00 43.78  ? 75  VAL F CB  1 
ATOM 3843 C CG1 . VAL D 4 75  ? 110.229 71.741  77.484  1.00 38.38  ? 75  VAL F CG1 1 
ATOM 3844 C CG2 . VAL D 4 75  ? 110.506 73.799  78.869  1.00 30.19  ? 75  VAL F CG2 1 
ATOM 3845 N N   . ARG D 4 76  ? 112.728 69.798  78.166  1.00 44.60  ? 76  ARG F N   1 
ATOM 3846 C CA  . ARG D 4 76  ? 113.307 68.673  77.448  1.00 53.09  ? 76  ARG F CA  1 
ATOM 3847 C C   . ARG D 4 76  ? 112.199 67.773  76.923  1.00 52.80  ? 76  ARG F C   1 
ATOM 3848 O O   . ARG D 4 76  ? 111.080 67.765  77.440  1.00 52.12  ? 76  ARG F O   1 
ATOM 3849 C CB  . ARG D 4 76  ? 114.261 67.859  78.337  1.00 57.49  ? 76  ARG F CB  1 
ATOM 3850 C CG  . ARG D 4 76  ? 113.598 67.097  79.484  1.00 55.37  ? 76  ARG F CG  1 
ATOM 3851 C CD  . ARG D 4 76  ? 114.549 66.070  80.075  1.00 51.13  ? 76  ARG F CD  1 
ATOM 3852 N NE  . ARG D 4 76  ? 113.863 65.100  80.923  1.00 55.93  ? 76  ARG F NE  1 
ATOM 3853 C CZ  . ARG D 4 76  ? 114.114 64.888  82.209  1.00 57.01  ? 76  ARG F CZ  1 
ATOM 3854 N NH1 . ARG D 4 76  ? 115.057 65.554  82.857  1.00 57.13  ? 76  ARG F NH1 1 
ATOM 3855 N NH2 . ARG D 4 76  ? 113.403 63.975  82.864  1.00 55.09  ? 76  ARG F NH2 1 
ATOM 3856 N N   . GLN D 4 77  ? 112.525 67.013  75.881  1.00 58.10  ? 77  GLN F N   1 
ATOM 3857 C CA  . GLN D 4 77  ? 111.616 66.010  75.348  1.00 62.20  ? 77  GLN F CA  1 
ATOM 3858 C C   . GLN D 4 77  ? 112.404 64.770  74.956  1.00 64.63  ? 77  GLN F C   1 
ATOM 3859 O O   . GLN D 4 77  ? 113.472 64.867  74.345  1.00 63.47  ? 77  GLN F O   1 
ATOM 3860 C CB  . GLN D 4 77  ? 110.832 66.539  74.138  1.00 63.18  ? 77  GLN F CB  1 
ATOM 3861 C CG  . GLN D 4 77  ? 111.687 67.011  72.976  1.00 61.36  ? 77  GLN F CG  1 
ATOM 3862 C CD  . GLN D 4 77  ? 110.897 67.115  71.690  1.00 63.61  ? 77  GLN F CD  1 
ATOM 3863 O OE1 . GLN D 4 77  ? 109.674 66.997  71.689  1.00 63.82  ? 77  GLN F OE1 1 
ATOM 3864 N NE2 . GLN D 4 77  ? 111.598 67.329  70.582  1.00 62.91  ? 77  GLN F NE2 1 
ATOM 3865 N N   . ALA D 4 78  ? 111.870 63.605  75.311  1.00 73.06  ? 78  ALA F N   1 
ATOM 3866 C CA  . ALA D 4 78  ? 112.501 62.355  74.941  1.00 74.24  ? 78  ALA F CA  1 
ATOM 3867 C C   . ALA D 4 78  ? 112.377 62.138  73.436  1.00 76.51  ? 78  ALA F C   1 
ATOM 3868 O O   . ALA D 4 78  ? 111.535 62.753  72.778  1.00 76.75  ? 78  ALA F O   1 
ATOM 3869 C CB  . ALA D 4 78  ? 111.865 61.191  75.695  1.00 74.23  ? 78  ALA F CB  1 
ATOM 3870 N N   . PRO D 4 79  ? 113.209 61.266  72.863  1.00 83.68  ? 79  PRO F N   1 
ATOM 3871 C CA  . PRO D 4 79  ? 113.162 61.069  71.405  1.00 83.07  ? 79  PRO F CA  1 
ATOM 3872 C C   . PRO D 4 79  ? 111.810 60.605  70.892  1.00 84.58  ? 79  PRO F C   1 
ATOM 3873 O O   . PRO D 4 79  ? 111.522 60.795  69.703  1.00 83.10  ? 79  PRO F O   1 
ATOM 3874 C CB  . PRO D 4 79  ? 114.247 60.011  71.160  1.00 82.96  ? 79  PRO F CB  1 
ATOM 3875 C CG  . PRO D 4 79  ? 115.170 60.141  72.314  1.00 81.83  ? 79  PRO F CG  1 
ATOM 3876 C CD  . PRO D 4 79  ? 114.310 60.510  73.482  1.00 82.18  ? 79  PRO F CD  1 
ATOM 3877 N N   . GLU D 4 80  ? 110.973 60.006  71.739  1.00 89.31  ? 80  GLU F N   1 
ATOM 3878 C CA  . GLU D 4 80  ? 109.665 59.517  71.326  1.00 88.03  ? 80  GLU F CA  1 
ATOM 3879 C C   . GLU D 4 80  ? 108.515 60.099  72.136  1.00 87.21  ? 80  GLU F C   1 
ATOM 3880 O O   . GLU D 4 80  ? 107.361 59.731  71.889  1.00 87.05  ? 80  GLU F O   1 
ATOM 3881 C CB  . GLU D 4 80  ? 109.622 57.986  71.422  1.00 88.38  ? 80  GLU F CB  1 
ATOM 3882 C CG  . GLU D 4 80  ? 110.636 57.276  70.536  1.00 88.23  ? 80  GLU F CG  1 
ATOM 3883 C CD  . GLU D 4 80  ? 110.343 57.445  69.058  1.00 88.47  ? 80  GLU F CD  1 
ATOM 3884 O OE1 . GLU D 4 80  ? 109.182 57.748  68.711  1.00 88.50  ? 80  GLU F OE1 1 
ATOM 3885 O OE2 . GLU D 4 80  ? 111.275 57.277  68.244  1.00 86.62  ? 80  GLU F OE2 1 
ATOM 3886 N N   . LYS D 4 81  ? 108.785 60.990  73.085  1.00 80.84  ? 81  LYS F N   1 
ATOM 3887 C CA  . LYS D 4 81  ? 107.766 61.541  73.970  1.00 79.31  ? 81  LYS F CA  1 
ATOM 3888 C C   . LYS D 4 81  ? 107.695 63.059  73.795  1.00 79.65  ? 81  LYS F C   1 
ATOM 3889 O O   . LYS D 4 81  ? 108.347 63.639  72.923  1.00 79.25  ? 81  LYS F O   1 
ATOM 3890 C CB  . LYS D 4 81  ? 108.056 61.156  75.423  1.00 80.63  ? 81  LYS F CB  1 
ATOM 3891 C CG  . LYS D 4 81  ? 108.453 59.698  75.622  1.00 81.96  ? 81  LYS F CG  1 
ATOM 3892 C CD  . LYS D 4 81  ? 107.364 58.743  75.160  1.00 82.33  ? 81  LYS F CD  1 
ATOM 3893 C CE  . LYS D 4 81  ? 107.829 57.298  75.228  1.00 81.47  ? 81  LYS F CE  1 
ATOM 3894 N NZ  . LYS D 4 81  ? 106.808 56.354  74.693  1.00 81.43  ? 81  LYS F NZ  1 
ATOM 3895 N N   . GLY D 4 82  ? 106.890 63.701  74.644  1.00 69.89  ? 82  GLY F N   1 
ATOM 3896 C CA  . GLY D 4 82  ? 106.632 65.119  74.548  1.00 67.23  ? 82  GLY F CA  1 
ATOM 3897 C C   . GLY D 4 82  ? 107.508 65.946  75.473  1.00 67.04  ? 82  GLY F C   1 
ATOM 3898 O O   . GLY D 4 82  ? 108.432 65.454  76.124  1.00 68.05  ? 82  GLY F O   1 
ATOM 3899 N N   . LEU D 4 83  ? 107.194 67.238  75.526  1.00 54.95  ? 83  LEU F N   1 
ATOM 3900 C CA  . LEU D 4 83  ? 107.969 68.186  76.312  1.00 49.31  ? 83  LEU F CA  1 
ATOM 3901 C C   . LEU D 4 83  ? 107.718 67.991  77.803  1.00 51.17  ? 83  LEU F C   1 
ATOM 3902 O O   . LEU D 4 83  ? 106.623 67.615  78.229  1.00 51.23  ? 83  LEU F O   1 
ATOM 3903 C CB  . LEU D 4 83  ? 107.616 69.617  75.910  1.00 52.22  ? 83  LEU F CB  1 
ATOM 3904 C CG  . LEU D 4 83  ? 107.762 69.959  74.426  1.00 52.45  ? 83  LEU F CG  1 
ATOM 3905 C CD1 . LEU D 4 83  ? 106.822 71.090  74.047  1.00 49.95  ? 83  LEU F CD1 1 
ATOM 3906 C CD2 . LEU D 4 83  ? 109.198 70.328  74.102  1.00 52.93  ? 83  LEU F CD2 1 
ATOM 3907 N N   . GLU D 4 84  ? 108.752 68.256  78.601  1.00 47.43  ? 84  GLU F N   1 
ATOM 3908 C CA  . GLU D 4 84  ? 108.683 68.111  80.051  1.00 42.76  ? 84  GLU F CA  1 
ATOM 3909 C C   . GLU D 4 84  ? 109.489 69.231  80.688  1.00 41.79  ? 84  GLU F C   1 
ATOM 3910 O O   . GLU D 4 84  ? 110.708 69.297  80.511  1.00 41.87  ? 84  GLU F O   1 
ATOM 3911 C CB  . GLU D 4 84  ? 109.211 66.741  80.491  1.00 39.53  ? 84  GLU F CB  1 
ATOM 3912 C CG  . GLU D 4 84  ? 108.647 66.236  81.814  1.00 44.27  ? 84  GLU F CG  1 
ATOM 3913 C CD  . GLU D 4 84  ? 109.440 66.701  83.022  1.00 47.01  ? 84  GLU F CD  1 
ATOM 3914 O OE1 . GLU D 4 84  ? 110.687 66.648  82.980  1.00 47.13  ? 84  GLU F OE1 1 
ATOM 3915 O OE2 . GLU D 4 84  ? 108.814 67.118  84.019  1.00 38.91  ? 84  GLU F OE2 1 
ATOM 3916 N N   . TRP D 4 85  ? 108.811 70.103  81.427  1.00 29.45  ? 85  TRP F N   1 
ATOM 3917 C CA  . TRP D 4 85  ? 109.471 71.231  82.069  1.00 25.51  ? 85  TRP F CA  1 
ATOM 3918 C C   . TRP D 4 85  ? 110.478 70.736  83.100  1.00 30.42  ? 85  TRP F C   1 
ATOM 3919 O O   . TRP D 4 85  ? 110.177 69.839  83.891  1.00 47.54  ? 85  TRP F O   1 
ATOM 3920 C CB  . TRP D 4 85  ? 108.426 72.126  82.726  1.00 28.96  ? 85  TRP F CB  1 
ATOM 3921 C CG  . TRP D 4 85  ? 108.977 73.281  83.489  1.00 30.40  ? 85  TRP F CG  1 
ATOM 3922 C CD1 . TRP D 4 85  ? 109.418 74.463  82.982  1.00 23.02  ? 85  TRP F CD1 1 
ATOM 3923 C CD2 . TRP D 4 85  ? 109.127 73.372  84.909  1.00 29.41  ? 85  TRP F CD2 1 
ATOM 3924 N NE1 . TRP D 4 85  ? 109.839 75.283  83.996  1.00 17.38  ? 85  TRP F NE1 1 
ATOM 3925 C CE2 . TRP D 4 85  ? 109.670 74.636  85.190  1.00 20.92  ? 85  TRP F CE2 1 
ATOM 3926 C CE3 . TRP D 4 85  ? 108.856 72.505  85.969  1.00 30.35  ? 85  TRP F CE3 1 
ATOM 3927 C CZ2 . TRP D 4 85  ? 109.950 75.055  86.485  1.00 21.82  ? 85  TRP F CZ2 1 
ATOM 3928 C CZ3 . TRP D 4 85  ? 109.133 72.923  87.250  1.00 33.40  ? 85  TRP F CZ3 1 
ATOM 3929 C CH2 . TRP D 4 85  ? 109.673 74.186  87.499  1.00 29.77  ? 85  TRP F CH2 1 
ATOM 3930 N N   . VAL D 4 86  ? 111.672 71.328  83.099  1.00 28.41  ? 86  VAL F N   1 
ATOM 3931 C CA  . VAL D 4 86  ? 112.785 70.878  83.934  1.00 19.39  ? 86  VAL F CA  1 
ATOM 3932 C C   . VAL D 4 86  ? 113.027 71.830  85.103  1.00 22.72  ? 86  VAL F C   1 
ATOM 3933 O O   . VAL D 4 86  ? 112.913 71.439  86.264  1.00 31.08  ? 86  VAL F O   1 
ATOM 3934 C CB  . VAL D 4 86  ? 114.067 70.688  83.092  1.00 32.32  ? 86  VAL F CB  1 
ATOM 3935 C CG1 . VAL D 4 86  ? 115.273 70.448  83.985  1.00 34.71  ? 86  VAL F CG1 1 
ATOM 3936 C CG2 . VAL D 4 86  ? 113.893 69.539  82.117  1.00 33.60  ? 86  VAL F CG2 1 
ATOM 3937 N N   . ALA D 4 87  ? 113.370 73.083  84.817  1.00 23.09  ? 87  ALA F N   1 
ATOM 3938 C CA  . ALA D 4 87  ? 113.742 74.020  85.869  1.00 20.77  ? 87  ALA F CA  1 
ATOM 3939 C C   . ALA D 4 87  ? 113.535 75.444  85.375  1.00 14.96  ? 87  ALA F C   1 
ATOM 3940 O O   . ALA D 4 87  ? 113.388 75.694  84.179  1.00 26.51  ? 87  ALA F O   1 
ATOM 3941 C CB  . ALA D 4 87  ? 115.189 73.803  86.313  1.00 37.68  ? 87  ALA F CB  1 
ATOM 3942 N N   . TYR D 4 88  ? 113.544 76.381  86.322  1.00 23.27  ? 88  TYR F N   1 
ATOM 3943 C CA  . TYR D 4 88  ? 113.203 77.771  86.058  1.00 37.82  ? 88  TYR F CA  1 
ATOM 3944 C C   . TYR D 4 88  ? 114.026 78.673  86.964  1.00 32.97  ? 88  TYR F C   1 
ATOM 3945 O O   . TYR D 4 88  ? 114.251 78.348  88.130  1.00 39.21  ? 88  TYR F O   1 
ATOM 3946 C CB  . TYR D 4 88  ? 111.704 78.014  86.289  1.00 26.83  ? 88  TYR F CB  1 
ATOM 3947 C CG  . TYR D 4 88  ? 111.323 79.461  86.490  1.00 20.14  ? 88  TYR F CG  1 
ATOM 3948 C CD1 . TYR D 4 88  ? 111.190 80.323  85.409  1.00 30.03  ? 88  TYR F CD1 1 
ATOM 3949 C CD2 . TYR D 4 88  ? 111.088 79.962  87.760  1.00 21.93  ? 88  TYR F CD2 1 
ATOM 3950 C CE1 . TYR D 4 88  ? 110.842 81.645  85.590  1.00 32.26  ? 88  TYR F CE1 1 
ATOM 3951 C CE2 . TYR D 4 88  ? 110.741 81.282  87.952  1.00 25.00  ? 88  TYR F CE2 1 
ATOM 3952 C CZ  . TYR D 4 88  ? 110.617 82.117  86.864  1.00 32.56  ? 88  TYR F CZ  1 
ATOM 3953 O OH  . TYR D 4 88  ? 110.267 83.432  87.054  1.00 33.27  ? 88  TYR F OH  1 
ATOM 3954 N N   . ILE D 4 89  ? 114.479 79.800  86.421  1.00 18.05  ? 89  ILE F N   1 
ATOM 3955 C CA  . ILE D 4 89  ? 115.153 80.834  87.200  1.00 17.28  ? 89  ILE F CA  1 
ATOM 3956 C C   . ILE D 4 89  ? 114.609 82.184  86.757  1.00 29.74  ? 89  ILE F C   1 
ATOM 3957 O O   . ILE D 4 89  ? 114.527 82.460  85.557  1.00 40.34  ? 89  ILE F O   1 
ATOM 3958 C CB  . ILE D 4 89  ? 116.687 80.778  87.040  1.00 37.59  ? 89  ILE F CB  1 
ATOM 3959 C CG1 . ILE D 4 89  ? 117.350 81.819  87.940  1.00 35.86  ? 89  ILE F CG1 1 
ATOM 3960 C CG2 . ILE D 4 89  ? 117.094 80.986  85.587  1.00 36.64  ? 89  ILE F CG2 1 
ATOM 3961 C CD1 . ILE D 4 89  ? 118.826 81.613  88.121  1.00 31.09  ? 89  ILE F CD1 1 
ATOM 3962 N N   . SER D 4 90  ? 114.243 83.025  87.720  1.00 39.13  ? 90  SER F N   1 
ATOM 3963 C CA  . SER D 4 90  ? 113.542 84.267  87.424  1.00 34.28  ? 90  SER F CA  1 
ATOM 3964 C C   . SER D 4 90  ? 114.543 85.354  87.036  1.00 36.96  ? 90  SER F C   1 
ATOM 3965 O O   . SER D 4 90  ? 115.740 85.107  86.871  1.00 36.18  ? 90  SER F O   1 
ATOM 3966 C CB  . SER D 4 90  ? 112.689 84.691  88.616  1.00 33.79  ? 90  SER F CB  1 
ATOM 3967 O OG  . SER D 4 90  ? 113.438 85.469  89.528  1.00 40.14  ? 90  SER F OG  1 
ATOM 3968 N N   . SER D 4 91  ? 114.047 86.578  86.876  1.00 45.22  ? 91  SER F N   1 
ATOM 3969 C CA  . SER D 4 91  ? 114.894 87.716  86.551  1.00 41.62  ? 91  SER F CA  1 
ATOM 3970 C C   . SER D 4 91  ? 115.499 88.281  87.829  1.00 41.18  ? 91  SER F C   1 
ATOM 3971 O O   . SER D 4 91  ? 114.786 88.541  88.804  1.00 36.47  ? 91  SER F O   1 
ATOM 3972 C CB  . SER D 4 91  ? 114.086 88.785  85.820  1.00 40.40  ? 91  SER F CB  1 
ATOM 3973 O OG  . SER D 4 91  ? 114.917 89.847  85.390  1.00 43.48  ? 91  SER F OG  1 
ATOM 3974 N N   . GLY D 4 92  ? 116.813 88.473  87.823  1.00 45.55  ? 92  GLY F N   1 
ATOM 3975 C CA  . GLY D 4 92  ? 117.537 88.817  89.026  1.00 49.36  ? 92  GLY F CA  1 
ATOM 3976 C C   . GLY D 4 92  ? 117.955 87.630  89.866  1.00 47.58  ? 92  GLY F C   1 
ATOM 3977 O O   . GLY D 4 92  ? 118.597 87.823  90.906  1.00 44.89  ? 92  GLY F O   1 
ATOM 3978 N N   . SER D 4 93  ? 117.606 86.412  89.453  1.00 47.46  ? 93  SER F N   1 
ATOM 3979 C CA  . SER D 4 93  ? 118.014 85.182  90.125  1.00 41.13  ? 93  SER F CA  1 
ATOM 3980 C C   . SER D 4 93  ? 117.408 85.053  91.517  1.00 44.10  ? 93  SER F C   1 
ATOM 3981 O O   . SER D 4 93  ? 117.894 84.269  92.337  1.00 47.85  ? 93  SER F O   1 
ATOM 3982 C CB  . SER D 4 93  ? 119.540 85.089  90.209  1.00 44.47  ? 93  SER F CB  1 
ATOM 3983 O OG  . SER D 4 93  ? 120.133 85.379  88.956  1.00 44.98  ? 93  SER F OG  1 
ATOM 3984 N N   . GLY D 4 94  ? 116.346 85.802  91.800  1.00 39.73  ? 94  GLY F N   1 
ATOM 3985 C CA  . GLY D 4 94  ? 115.737 85.799  93.112  1.00 40.08  ? 94  GLY F CA  1 
ATOM 3986 C C   . GLY D 4 94  ? 114.768 84.674  93.381  1.00 40.45  ? 94  GLY F C   1 
ATOM 3987 O O   . GLY D 4 94  ? 114.227 84.592  94.486  1.00 43.77  ? 94  GLY F O   1 
ATOM 3988 N N   . THR D 4 95  ? 114.529 83.799  92.407  1.00 38.36  ? 95  THR F N   1 
ATOM 3989 C CA  . THR D 4 95  ? 113.570 82.715  92.568  1.00 39.72  ? 95  THR F CA  1 
ATOM 3990 C C   . THR D 4 95  ? 113.953 81.593  91.617  1.00 34.82  ? 95  THR F C   1 
ATOM 3991 O O   . THR D 4 95  ? 114.232 81.846  90.443  1.00 43.92  ? 95  THR F O   1 
ATOM 3992 C CB  . THR D 4 95  ? 112.141 83.202  92.289  1.00 39.46  ? 95  THR F CB  1 
ATOM 3993 O OG1 . THR D 4 95  ? 111.805 84.255  93.200  1.00 35.65  ? 95  THR F OG1 1 
ATOM 3994 C CG2 . THR D 4 95  ? 111.141 82.075  92.442  1.00 32.34  ? 95  THR F CG2 1 
ATOM 3995 N N   . ILE D 4 96  ? 113.976 80.365  92.124  1.00 16.38  ? 96  ILE F N   1 
ATOM 3996 C CA  . ILE D 4 96  ? 114.372 79.195  91.353  1.00 19.05  ? 96  ILE F CA  1 
ATOM 3997 C C   . ILE D 4 96  ? 113.389 78.073  91.649  1.00 26.02  ? 96  ILE F C   1 
ATOM 3998 O O   . ILE D 4 96  ? 112.914 77.936  92.781  1.00 36.28  ? 96  ILE F O   1 
ATOM 3999 C CB  . ILE D 4 96  ? 115.819 78.763  91.682  1.00 36.17  ? 96  ILE F CB  1 
ATOM 4000 C CG1 . ILE D 4 96  ? 116.782 79.929  91.449  1.00 34.48  ? 96  ILE F CG1 1 
ATOM 4001 C CG2 . ILE D 4 96  ? 116.233 77.562  90.843  1.00 35.45  ? 96  ILE F CG2 1 
ATOM 4002 C CD1 . ILE D 4 96  ? 118.224 79.619  91.766  1.00 28.08  ? 96  ILE F CD1 1 
ATOM 4003 N N   . TYR D 4 97  ? 113.073 77.281  90.629  1.00 19.80  ? 97  TYR F N   1 
ATOM 4004 C CA  . TYR D 4 97  ? 112.183 76.142  90.775  1.00 27.64  ? 97  TYR F CA  1 
ATOM 4005 C C   . TYR D 4 97  ? 112.763 74.958  90.022  1.00 21.71  ? 97  TYR F C   1 
ATOM 4006 O O   . TYR D 4 97  ? 113.520 75.123  89.064  1.00 26.31  ? 97  TYR F O   1 
ATOM 4007 C CB  . TYR D 4 97  ? 110.768 76.452  90.264  1.00 31.66  ? 97  TYR F CB  1 
ATOM 4008 C CG  . TYR D 4 97  ? 109.948 77.275  91.224  1.00 22.18  ? 97  TYR F CG  1 
ATOM 4009 C CD1 . TYR D 4 97  ? 110.029 78.659  91.228  1.00 27.69  ? 97  TYR F CD1 1 
ATOM 4010 C CD2 . TYR D 4 97  ? 109.099 76.667  92.134  1.00 29.56  ? 97  TYR F CD2 1 
ATOM 4011 C CE1 . TYR D 4 97  ? 109.283 79.414  92.109  1.00 35.16  ? 97  TYR F CE1 1 
ATOM 4012 C CE2 . TYR D 4 97  ? 108.350 77.413  93.020  1.00 33.26  ? 97  TYR F CE2 1 
ATOM 4013 C CZ  . TYR D 4 97  ? 108.447 78.787  93.004  1.00 37.82  ? 97  TYR F CZ  1 
ATOM 4014 O OH  . TYR D 4 97  ? 107.701 79.538  93.883  1.00 32.37  ? 97  TYR F OH  1 
ATOM 4015 N N   . TYR D 4 98  ? 112.400 73.760  90.471  1.00 27.23  ? 98  TYR F N   1 
ATOM 4016 C CA  . TYR D 4 98  ? 112.889 72.524  89.883  1.00 28.15  ? 98  TYR F CA  1 
ATOM 4017 C C   . TYR D 4 98  ? 111.745 71.530  89.793  1.00 27.58  ? 98  TYR F C   1 
ATOM 4018 O O   . TYR D 4 98  ? 110.742 71.640  90.501  1.00 40.17  ? 98  TYR F O   1 
ATOM 4019 C CB  . TYR D 4 98  ? 114.031 71.912  90.702  1.00 42.73  ? 98  TYR F CB  1 
ATOM 4020 C CG  . TYR D 4 98  ? 115.307 72.715  90.698  1.00 42.67  ? 98  TYR F CG  1 
ATOM 4021 C CD1 . TYR D 4 98  ? 116.234 72.574  89.676  1.00 36.51  ? 98  TYR F CD1 1 
ATOM 4022 C CD2 . TYR D 4 98  ? 115.589 73.604  91.722  1.00 38.01  ? 98  TYR F CD2 1 
ATOM 4023 C CE1 . TYR D 4 98  ? 117.400 73.304  89.672  1.00 38.97  ? 98  TYR F CE1 1 
ATOM 4024 C CE2 . TYR D 4 98  ? 116.752 74.336  91.726  1.00 35.24  ? 98  TYR F CE2 1 
ATOM 4025 C CZ  . TYR D 4 98  ? 117.654 74.182  90.701  1.00 43.57  ? 98  TYR F CZ  1 
ATOM 4026 O OH  . TYR D 4 98  ? 118.818 74.912  90.706  1.00 47.51  ? 98  TYR F OH  1 
ATOM 4027 N N   . ALA D 4 99  ? 111.906 70.556  88.908  1.00 35.19  ? 99  ALA F N   1 
ATOM 4028 C CA  . ALA D 4 99  ? 110.962 69.456  88.839  1.00 44.55  ? 99  ALA F CA  1 
ATOM 4029 C C   . ALA D 4 99  ? 111.237 68.463  89.962  1.00 51.62  ? 99  ALA F C   1 
ATOM 4030 O O   . ALA D 4 99  ? 112.324 68.423  90.542  1.00 53.78  ? 99  ALA F O   1 
ATOM 4031 C CB  . ALA D 4 99  ? 111.043 68.754  87.485  1.00 43.62  ? 99  ALA F CB  1 
ATOM 4032 N N   . ASP D 4 100 ? 110.229 67.652  90.264  1.00 68.67  ? 100 ASP F N   1 
ATOM 4033 C CA  . ASP D 4 100 ? 110.349 66.659  91.323  1.00 67.81  ? 100 ASP F CA  1 
ATOM 4034 C C   . ASP D 4 100 ? 111.047 65.388  90.860  1.00 66.68  ? 100 ASP F C   1 
ATOM 4035 O O   . ASP D 4 100 ? 111.224 64.472  91.669  1.00 68.79  ? 100 ASP F O   1 
ATOM 4036 C CB  . ASP D 4 100 ? 108.965 66.319  91.885  1.00 68.55  ? 100 ASP F CB  1 
ATOM 4037 C CG  . ASP D 4 100 ? 107.971 65.934  90.807  1.00 72.36  ? 100 ASP F CG  1 
ATOM 4038 O OD1 . ASP D 4 100 ? 108.377 65.834  89.630  1.00 73.51  ? 100 ASP F OD1 1 
ATOM 4039 O OD2 . ASP D 4 100 ? 106.783 65.736  91.135  1.00 69.38  ? 100 ASP F OD2 1 
ATOM 4040 N N   . THR D 4 101 ? 111.443 65.309  89.590  1.00 61.86  ? 101 THR F N   1 
ATOM 4041 C CA  . THR D 4 101 ? 112.159 64.156  89.067  1.00 67.15  ? 101 THR F CA  1 
ATOM 4042 C C   . THR D 4 101 ? 113.644 64.413  88.857  1.00 67.26  ? 101 THR F C   1 
ATOM 4043 O O   . THR D 4 101 ? 114.386 63.459  88.598  1.00 63.77  ? 101 THR F O   1 
ATOM 4044 C CB  . THR D 4 101 ? 111.540 63.706  87.736  1.00 65.92  ? 101 THR F CB  1 
ATOM 4045 O OG1 . THR D 4 101 ? 111.912 64.618  86.698  1.00 59.58  ? 101 THR F OG1 1 
ATOM 4046 C CG2 . THR D 4 101 ? 110.022 63.659  87.841  1.00 68.12  ? 101 THR F CG2 1 
ATOM 4047 N N   . VAL D 4 102 ? 114.097 65.664  88.954  1.00 66.25  ? 102 VAL F N   1 
ATOM 4048 C CA  . VAL D 4 102 ? 115.508 65.992  88.775  1.00 65.65  ? 102 VAL F CA  1 
ATOM 4049 C C   . VAL D 4 102 ? 115.999 66.837  89.943  1.00 66.13  ? 102 VAL F C   1 
ATOM 4050 O O   . VAL D 4 102 ? 117.089 67.414  89.884  1.00 68.45  ? 102 VAL F O   1 
ATOM 4051 C CB  . VAL D 4 102 ? 115.751 66.729  87.445  1.00 66.64  ? 102 VAL F CB  1 
ATOM 4052 C CG1 . VAL D 4 102 ? 115.314 65.874  86.271  1.00 65.52  ? 102 VAL F CG1 1 
ATOM 4053 C CG2 . VAL D 4 102 ? 115.036 68.074  87.434  1.00 63.57  ? 102 VAL F CG2 1 
ATOM 4054 N N   . LYS D 4 103 ? 115.208 66.920  91.008  1.00 63.74  ? 103 LYS F N   1 
ATOM 4055 C CA  . LYS D 4 103 ? 115.578 67.769  92.130  1.00 63.74  ? 103 LYS F CA  1 
ATOM 4056 C C   . LYS D 4 103 ? 116.810 67.214  92.834  1.00 64.77  ? 103 LYS F C   1 
ATOM 4057 O O   . LYS D 4 103 ? 116.941 66.003  93.031  1.00 62.86  ? 103 LYS F O   1 
ATOM 4058 C CB  . LYS D 4 103 ? 114.415 67.893  93.115  1.00 61.12  ? 103 LYS F CB  1 
ATOM 4059 C CG  . LYS D 4 103 ? 114.693 68.801  94.308  1.00 63.40  ? 103 LYS F CG  1 
ATOM 4060 C CD  . LYS D 4 103 ? 115.110 70.199  93.879  1.00 61.25  ? 103 LYS F CD  1 
ATOM 4061 C CE  . LYS D 4 103 ? 115.324 71.114  95.069  1.00 60.98  ? 103 LYS F CE  1 
ATOM 4062 N NZ  . LYS D 4 103 ? 114.044 71.451  95.746  1.00 60.67  ? 103 LYS F NZ  1 
ATOM 4063 N N   . GLY D 4 104 ? 117.708 68.105  93.210  1.00 69.21  ? 104 GLY F N   1 
ATOM 4064 C CA  . GLY D 4 104 ? 118.956 67.725  93.864  1.00 69.93  ? 104 GLY F CA  1 
ATOM 4065 C C   . GLY D 4 104 ? 120.116 67.505  92.918  1.00 71.53  ? 104 GLY F C   1 
ATOM 4066 O O   . GLY D 4 104 ? 121.208 68.024  93.141  1.00 72.37  ? 104 GLY F O   1 
ATOM 4067 N N   . ARG D 4 105 ? 119.891 66.737  91.851  1.00 70.25  ? 105 ARG F N   1 
ATOM 4068 C CA  . ARG D 4 105 ? 120.973 66.408  90.929  1.00 69.69  ? 105 ARG F CA  1 
ATOM 4069 C C   . ARG D 4 105 ? 121.316 67.578  90.014  1.00 70.44  ? 105 ARG F C   1 
ATOM 4070 O O   . ARG D 4 105 ? 122.495 67.835  89.747  1.00 71.83  ? 105 ARG F O   1 
ATOM 4071 C CB  . ARG D 4 105 ? 120.597 65.182  90.096  1.00 70.10  ? 105 ARG F CB  1 
ATOM 4072 C CG  . ARG D 4 105 ? 119.787 64.140  90.844  1.00 70.15  ? 105 ARG F CG  1 
ATOM 4073 C CD  . ARG D 4 105 ? 119.925 62.766  90.215  1.00 68.92  ? 105 ARG F CD  1 
ATOM 4074 N NE  . ARG D 4 105 ? 119.856 62.808  88.759  1.00 68.91  ? 105 ARG F NE  1 
ATOM 4075 C CZ  . ARG D 4 105 ? 118.735 62.759  88.052  1.00 70.98  ? 105 ARG F CZ  1 
ATOM 4076 N NH1 . ARG D 4 105 ? 117.549 62.703  88.635  1.00 72.89  ? 105 ARG F NH1 1 
ATOM 4077 N NH2 . ARG D 4 105 ? 118.806 62.770  86.724  1.00 71.70  ? 105 ARG F NH2 1 
ATOM 4078 N N   . PHE D 4 106 ? 120.310 68.295  89.527  1.00 64.95  ? 106 PHE F N   1 
ATOM 4079 C CA  . PHE D 4 106 ? 120.495 69.369  88.562  1.00 65.42  ? 106 PHE F CA  1 
ATOM 4080 C C   . PHE D 4 106 ? 120.581 70.718  89.264  1.00 66.35  ? 106 PHE F C   1 
ATOM 4081 O O   . PHE D 4 106 ? 120.214 70.865  90.432  1.00 65.73  ? 106 PHE F O   1 
ATOM 4082 C CB  . PHE D 4 106 ? 119.348 69.388  87.548  1.00 67.06  ? 106 PHE F CB  1 
ATOM 4083 C CG  . PHE D 4 106 ? 119.417 68.291  86.526  1.00 65.85  ? 106 PHE F CG  1 
ATOM 4084 C CD1 . PHE D 4 106 ? 119.492 66.965  86.910  1.00 65.43  ? 106 PHE F CD1 1 
ATOM 4085 C CD2 . PHE D 4 106 ? 119.386 68.588  85.176  1.00 65.63  ? 106 PHE F CD2 1 
ATOM 4086 C CE1 . PHE D 4 106 ? 119.548 65.958  85.969  1.00 65.87  ? 106 PHE F CE1 1 
ATOM 4087 C CE2 . PHE D 4 106 ? 119.440 67.582  84.230  1.00 67.24  ? 106 PHE F CE2 1 
ATOM 4088 C CZ  . PHE D 4 106 ? 119.521 66.268  84.629  1.00 67.16  ? 106 PHE F CZ  1 
ATOM 4089 N N   . THR D 4 107 ? 121.077 71.710  88.529  1.00 58.97  ? 107 THR F N   1 
ATOM 4090 C CA  . THR D 4 107 ? 121.178 73.070  89.034  1.00 55.99  ? 107 THR F CA  1 
ATOM 4091 C C   . THR D 4 107 ? 121.070 74.034  87.861  1.00 57.59  ? 107 THR F C   1 
ATOM 4092 O O   . THR D 4 107 ? 121.542 73.735  86.762  1.00 55.37  ? 107 THR F O   1 
ATOM 4093 C CB  . THR D 4 107 ? 122.496 73.290  89.787  1.00 60.03  ? 107 THR F CB  1 
ATOM 4094 O OG1 . THR D 4 107 ? 122.666 72.256  90.763  1.00 59.31  ? 107 THR F OG1 1 
ATOM 4095 C CG2 . THR D 4 107 ? 122.499 74.641  90.484  1.00 58.15  ? 107 THR F CG2 1 
ATOM 4096 N N   . ILE D 4 108 ? 120.451 75.188  88.103  1.00 51.52  ? 108 ILE F N   1 
ATOM 4097 C CA  . ILE D 4 108 ? 120.234 76.203  87.079  1.00 48.20  ? 108 ILE F CA  1 
ATOM 4098 C C   . ILE D 4 108 ? 120.780 77.530  87.584  1.00 44.51  ? 108 ILE F C   1 
ATOM 4099 O O   . ILE D 4 108 ? 120.535 77.918  88.731  1.00 48.27  ? 108 ILE F O   1 
ATOM 4100 C CB  . ILE D 4 108 ? 118.738 76.333  86.706  1.00 49.11  ? 108 ILE F CB  1 
ATOM 4101 C CG1 . ILE D 4 108 ? 118.552 77.355  85.584  1.00 49.93  ? 108 ILE F CG1 1 
ATOM 4102 C CG2 . ILE D 4 108 ? 117.907 76.732  87.915  1.00 39.67  ? 108 ILE F CG2 1 
ATOM 4103 C CD1 . ILE D 4 108 ? 117.146 77.431  85.053  1.00 43.18  ? 108 ILE F CD1 1 
ATOM 4104 N N   . SER D 4 109 ? 121.526 78.224  86.727  1.00 40.53  ? 109 SER F N   1 
ATOM 4105 C CA  . SER D 4 109 ? 122.059 79.534  87.064  1.00 42.22  ? 109 SER F CA  1 
ATOM 4106 C C   . SER D 4 109 ? 122.263 80.321  85.779  1.00 43.73  ? 109 SER F C   1 
ATOM 4107 O O   . SER D 4 109 ? 122.337 79.754  84.686  1.00 40.81  ? 109 SER F O   1 
ATOM 4108 C CB  . SER D 4 109 ? 123.371 79.429  87.851  1.00 50.68  ? 109 SER F CB  1 
ATOM 4109 O OG  . SER D 4 109 ? 124.370 78.753  87.108  1.00 49.42  ? 109 SER F OG  1 
ATOM 4110 N N   . ARG D 4 110 ? 122.350 81.641  85.925  1.00 44.51  ? 110 ARG F N   1 
ATOM 4111 C CA  . ARG D 4 110 ? 122.447 82.553  84.795  1.00 45.06  ? 110 ARG F CA  1 
ATOM 4112 C C   . ARG D 4 110 ? 123.546 83.571  85.047  1.00 44.79  ? 110 ARG F C   1 
ATOM 4113 O O   . ARG D 4 110 ? 123.752 84.007  86.183  1.00 46.85  ? 110 ARG F O   1 
ATOM 4114 C CB  . ARG D 4 110 ? 121.114 83.278  84.554  1.00 46.51  ? 110 ARG F CB  1 
ATOM 4115 C CG  . ARG D 4 110 ? 120.682 84.174  85.703  1.00 44.64  ? 110 ARG F CG  1 
ATOM 4116 C CD  . ARG D 4 110 ? 119.227 84.581  85.583  1.00 42.05  ? 110 ARG F CD  1 
ATOM 4117 N NE  . ARG D 4 110 ? 118.973 85.379  84.391  1.00 52.32  ? 110 ARG F NE  1 
ATOM 4118 C CZ  . ARG D 4 110 ? 117.770 85.766  83.990  1.00 50.00  ? 110 ARG F CZ  1 
ATOM 4119 N NH1 . ARG D 4 110 ? 116.679 85.441  84.663  1.00 38.16  ? 110 ARG F NH1 1 
ATOM 4120 N NH2 . ARG D 4 110 ? 117.658 86.495  82.885  1.00 41.80  ? 110 ARG F NH2 1 
ATOM 4121 N N   . ASP D 4 111 ? 124.246 83.947  83.979  1.00 56.95  ? 111 ASP F N   1 
ATOM 4122 C CA  . ASP D 4 111 ? 125.243 85.012  84.010  1.00 58.27  ? 111 ASP F CA  1 
ATOM 4123 C C   . ASP D 4 111 ? 124.729 86.141  83.126  1.00 54.56  ? 111 ASP F C   1 
ATOM 4124 O O   . ASP D 4 111 ? 124.658 85.995  81.901  1.00 52.31  ? 111 ASP F O   1 
ATOM 4125 C CB  . ASP D 4 111 ? 126.605 84.509  83.536  1.00 59.76  ? 111 ASP F CB  1 
ATOM 4126 C CG  . ASP D 4 111 ? 127.738 85.456  83.892  1.00 58.89  ? 111 ASP F CG  1 
ATOM 4127 O OD1 . ASP D 4 111 ? 127.561 86.290  84.804  1.00 60.13  ? 111 ASP F OD1 1 
ATOM 4128 O OD2 . ASP D 4 111 ? 128.810 85.365  83.259  1.00 56.36  ? 111 ASP F OD2 1 
ATOM 4129 N N   . ASP D 4 112 ? 124.367 87.258  83.745  1.00 59.95  ? 112 ASP F N   1 
ATOM 4130 C CA  . ASP D 4 112 ? 123.781 88.384  83.031  1.00 67.46  ? 112 ASP F CA  1 
ATOM 4131 C C   . ASP D 4 112 ? 124.819 89.153  82.220  1.00 66.52  ? 112 ASP F C   1 
ATOM 4132 O O   . ASP D 4 112 ? 124.588 89.419  81.034  1.00 62.35  ? 112 ASP F O   1 
ATOM 4133 C CB  . ASP D 4 112 ? 123.077 89.321  84.013  1.00 65.40  ? 112 ASP F CB  1 
ATOM 4134 C CG  . ASP D 4 112 ? 121.778 88.744  84.537  1.00 63.85  ? 112 ASP F CG  1 
ATOM 4135 O OD1 . ASP D 4 112 ? 121.150 87.941  83.817  1.00 62.85  ? 112 ASP F OD1 1 
ATOM 4136 O OD2 . ASP D 4 112 ? 121.386 89.093  85.669  1.00 60.68  ? 112 ASP F OD2 1 
ATOM 4137 N N   . PRO D 4 113 ? 125.962 89.538  82.799  1.00 69.63  ? 113 PRO F N   1 
ATOM 4138 C CA  . PRO D 4 113 ? 126.949 90.279  81.997  1.00 66.99  ? 113 PRO F CA  1 
ATOM 4139 C C   . PRO D 4 113 ? 127.421 89.522  80.768  1.00 67.75  ? 113 PRO F C   1 
ATOM 4140 O O   . PRO D 4 113 ? 127.751 90.153  79.756  1.00 67.53  ? 113 PRO F O   1 
ATOM 4141 C CB  . PRO D 4 113 ? 128.097 90.531  82.987  1.00 68.26  ? 113 PRO F CB  1 
ATOM 4142 C CG  . PRO D 4 113 ? 127.855 89.615  84.128  1.00 68.97  ? 113 PRO F CG  1 
ATOM 4143 C CD  . PRO D 4 113 ? 126.379 89.445  84.208  1.00 68.23  ? 113 PRO F CD  1 
ATOM 4144 N N   . LYS D 4 114 ? 127.463 88.193  80.820  1.00 64.48  ? 114 LYS F N   1 
ATOM 4145 C CA  . LYS D 4 114 ? 127.859 87.378  79.679  1.00 65.67  ? 114 LYS F CA  1 
ATOM 4146 C C   . LYS D 4 114 ? 126.674 86.821  78.902  1.00 67.19  ? 114 LYS F C   1 
ATOM 4147 O O   . LYS D 4 114 ? 126.882 86.100  77.921  1.00 64.21  ? 114 LYS F O   1 
ATOM 4148 C CB  . LYS D 4 114 ? 128.756 86.228  80.145  1.00 64.21  ? 114 LYS F CB  1 
ATOM 4149 C CG  . LYS D 4 114 ? 130.084 86.691  80.716  1.00 64.84  ? 114 LYS F CG  1 
ATOM 4150 C CD  . LYS D 4 114 ? 131.013 85.525  80.998  1.00 65.75  ? 114 LYS F CD  1 
ATOM 4151 C CE  . LYS D 4 114 ? 132.319 85.998  81.612  1.00 65.21  ? 114 LYS F CE  1 
ATOM 4152 N NZ  . LYS D 4 114 ? 133.218 84.865  81.963  1.00 66.27  ? 114 LYS F NZ  1 
ATOM 4153 N N   . ASN D 4 115 ? 125.442 87.138  79.309  1.00 58.58  ? 115 ASN F N   1 
ATOM 4154 C CA  . ASN D 4 115 ? 124.243 86.733  78.572  1.00 55.80  ? 115 ASN F CA  1 
ATOM 4155 C C   . ASN D 4 115 ? 124.206 85.223  78.355  1.00 56.79  ? 115 ASN F C   1 
ATOM 4156 O O   . ASN D 4 115 ? 123.916 84.741  77.259  1.00 58.64  ? 115 ASN F O   1 
ATOM 4157 C CB  . ASN D 4 115 ? 124.153 87.466  77.233  1.00 57.73  ? 115 ASN F CB  1 
ATOM 4158 C CG  . ASN D 4 115 ? 123.914 88.952  77.395  1.00 60.23  ? 115 ASN F CG  1 
ATOM 4159 O OD1 . ASN D 4 115 ? 123.980 89.487  78.499  1.00 60.49  ? 115 ASN F OD1 1 
ATOM 4160 N ND2 . ASN D 4 115 ? 123.640 89.628  76.287  1.00 57.26  ? 115 ASN F ND2 1 
ATOM 4161 N N   . THR D 4 116 ? 124.497 84.467  79.411  1.00 54.98  ? 116 THR F N   1 
ATOM 4162 C CA  . THR D 4 116 ? 124.594 83.017  79.327  1.00 54.64  ? 116 THR F CA  1 
ATOM 4163 C C   . THR D 4 116 ? 123.745 82.371  80.412  1.00 53.38  ? 116 THR F C   1 
ATOM 4164 O O   . THR D 4 116 ? 123.690 82.860  81.543  1.00 54.72  ? 116 THR F O   1 
ATOM 4165 C CB  . THR D 4 116 ? 126.054 82.549  79.459  1.00 59.82  ? 116 THR F CB  1 
ATOM 4166 O OG1 . THR D 4 116 ? 126.885 83.306  78.572  1.00 63.03  ? 116 THR F OG1 1 
ATOM 4167 C CG2 . THR D 4 116 ? 126.179 81.073  79.119  1.00 56.56  ? 116 THR F CG2 1 
ATOM 4168 N N   . LEU D 4 117 ? 123.087 81.270  80.054  1.00 53.16  ? 117 LEU F N   1 
ATOM 4169 C CA  . LEU D 4 117 ? 122.296 80.467  80.977  1.00 54.57  ? 117 LEU F CA  1 
ATOM 4170 C C   . LEU D 4 117 ? 122.900 79.072  81.048  1.00 51.46  ? 117 LEU F C   1 
ATOM 4171 O O   . LEU D 4 117 ? 123.220 78.480  80.012  1.00 49.98  ? 117 LEU F O   1 
ATOM 4172 C CB  . LEU D 4 117 ? 120.833 80.391  80.530  1.00 51.89  ? 117 LEU F CB  1 
ATOM 4173 C CG  . LEU D 4 117 ? 119.870 79.663  81.471  1.00 47.56  ? 117 LEU F CG  1 
ATOM 4174 C CD1 . LEU D 4 117 ? 119.478 80.552  82.638  1.00 49.41  ? 117 LEU F CD1 1 
ATOM 4175 C CD2 . LEU D 4 117 ? 118.646 79.182  80.721  1.00 46.31  ? 117 LEU F CD2 1 
ATOM 4176 N N   . PHE D 4 118 ? 123.045 78.548  82.263  1.00 50.64  ? 118 PHE F N   1 
ATOM 4177 C CA  . PHE D 4 118 ? 123.711 77.275  82.495  1.00 53.38  ? 118 PHE F CA  1 
ATOM 4178 C C   . PHE D 4 118 ? 122.751 76.266  83.110  1.00 54.49  ? 118 PHE F C   1 
ATOM 4179 O O   . PHE D 4 118 ? 121.808 76.629  83.818  1.00 49.08  ? 118 PHE F O   1 
ATOM 4180 C CB  . PHE D 4 118 ? 124.917 77.440  83.422  1.00 53.80  ? 118 PHE F CB  1 
ATOM 4181 C CG  . PHE D 4 118 ? 125.775 78.622  83.095  1.00 55.29  ? 118 PHE F CG  1 
ATOM 4182 C CD1 . PHE D 4 118 ? 126.691 78.566  82.059  1.00 53.72  ? 118 PHE F CD1 1 
ATOM 4183 C CD2 . PHE D 4 118 ? 125.671 79.788  83.830  1.00 52.57  ? 118 PHE F CD2 1 
ATOM 4184 C CE1 . PHE D 4 118 ? 127.484 79.653  81.761  1.00 53.12  ? 118 PHE F CE1 1 
ATOM 4185 C CE2 . PHE D 4 118 ? 126.460 80.878  83.537  1.00 52.52  ? 118 PHE F CE2 1 
ATOM 4186 C CZ  . PHE D 4 118 ? 127.367 80.812  82.501  1.00 55.50  ? 118 PHE F CZ  1 
ATOM 4187 N N   . LEU D 4 119 ? 123.008 74.989  82.828  1.00 58.82  ? 119 LEU F N   1 
ATOM 4188 C CA  . LEU D 4 119 ? 122.305 73.878  83.471  1.00 61.77  ? 119 LEU F CA  1 
ATOM 4189 C C   . LEU D 4 119 ? 123.358 72.837  83.840  1.00 61.15  ? 119 LEU F C   1 
ATOM 4190 O O   . LEU D 4 119 ? 123.836 72.096  82.975  1.00 57.05  ? 119 LEU F O   1 
ATOM 4191 C CB  . LEU D 4 119 ? 121.233 73.285  82.564  1.00 59.97  ? 119 LEU F CB  1 
ATOM 4192 C CG  . LEU D 4 119 ? 120.473 72.073  83.110  1.00 56.10  ? 119 LEU F CG  1 
ATOM 4193 C CD1 . LEU D 4 119 ? 119.636 72.456  84.314  1.00 55.37  ? 119 LEU F CD1 1 
ATOM 4194 C CD2 . LEU D 4 119 ? 119.606 71.450  82.030  1.00 55.95  ? 119 LEU F CD2 1 
ATOM 4195 N N   . GLN D 4 120 ? 123.713 72.785  85.121  1.00 65.30  ? 120 GLN F N   1 
ATOM 4196 C CA  . GLN D 4 120 ? 124.697 71.842  85.634  1.00 63.68  ? 120 GLN F CA  1 
ATOM 4197 C C   . GLN D 4 120 ? 123.964 70.619  86.165  1.00 63.58  ? 120 GLN F C   1 
ATOM 4198 O O   . GLN D 4 120 ? 123.087 70.745  87.025  1.00 66.19  ? 120 GLN F O   1 
ATOM 4199 C CB  . GLN D 4 120 ? 125.544 72.480  86.734  1.00 63.59  ? 120 GLN F CB  1 
ATOM 4200 C CG  . GLN D 4 120 ? 126.125 73.841  86.375  1.00 66.37  ? 120 GLN F CG  1 
ATOM 4201 C CD  . GLN D 4 120 ? 125.147 74.977  86.607  1.00 64.42  ? 120 GLN F CD  1 
ATOM 4202 O OE1 . GLN D 4 120 ? 123.981 74.752  86.926  1.00 64.07  ? 120 GLN F OE1 1 
ATOM 4203 N NE2 . GLN D 4 120 ? 125.621 76.208  86.449  1.00 60.95  ? 120 GLN F NE2 1 
ATOM 4204 N N   . MET D 4 121 ? 124.322 69.443  85.656  1.00 67.66  ? 121 MET F N   1 
ATOM 4205 C CA  . MET D 4 121 ? 123.642 68.204  86.004  1.00 71.76  ? 121 MET F CA  1 
ATOM 4206 C C   . MET D 4 121 ? 124.655 67.149  86.422  1.00 71.67  ? 121 MET F C   1 
ATOM 4207 O O   . MET D 4 121 ? 125.737 67.046  85.836  1.00 70.93  ? 121 MET F O   1 
ATOM 4208 C CB  . MET D 4 121 ? 122.803 67.691  84.830  1.00 71.97  ? 121 MET F CB  1 
ATOM 4209 C CG  . MET D 4 121 ? 123.575 67.505  83.539  1.00 73.08  ? 121 MET F CG  1 
ATOM 4210 S SD  . MET D 4 121 ? 122.503 67.158  82.134  1.00 71.07  ? 121 MET F SD  1 
ATOM 4211 C CE  . MET D 4 121 ? 121.771 68.766  81.871  1.00 68.72  ? 121 MET F CE  1 
ATOM 4212 N N   . THR D 4 122 ? 124.294 66.369  87.440  1.00 76.38  ? 122 THR F N   1 
ATOM 4213 C CA  . THR D 4 122 ? 125.155 65.336  87.994  1.00 77.52  ? 122 THR F CA  1 
ATOM 4214 C C   . THR D 4 122 ? 124.353 64.057  88.182  1.00 77.65  ? 122 THR F C   1 
ATOM 4215 O O   . THR D 4 122 ? 123.122 64.076  88.254  1.00 79.93  ? 122 THR F O   1 
ATOM 4216 C CB  . THR D 4 122 ? 125.762 65.761  89.340  1.00 77.38  ? 122 THR F CB  1 
ATOM 4217 O OG1 . THR D 4 122 ? 124.731 65.833  90.331  1.00 75.28  ? 122 THR F OG1 1 
ATOM 4218 C CG2 . THR D 4 122 ? 126.444 67.115  89.223  1.00 75.80  ? 122 THR F CG2 1 
ATOM 4219 N N   . SER D 4 123 ? 125.069 62.935  88.253  1.00 81.30  ? 123 SER F N   1 
ATOM 4220 C CA  . SER D 4 123 ? 124.466 61.629  88.513  1.00 80.82  ? 123 SER F CA  1 
ATOM 4221 C C   . SER D 4 123 ? 123.403 61.302  87.463  1.00 81.75  ? 123 SER F C   1 
ATOM 4222 O O   . SER D 4 123 ? 122.239 61.039  87.771  1.00 82.36  ? 123 SER F O   1 
ATOM 4223 C CB  . SER D 4 123 ? 123.876 61.582  89.925  1.00 79.90  ? 123 SER F CB  1 
ATOM 4224 O OG  . SER D 4 123 ? 124.840 61.963  90.890  1.00 80.54  ? 123 SER F OG  1 
ATOM 4225 N N   . LEU D 4 124 ? 123.829 61.322  86.204  1.00 84.31  ? 124 LEU F N   1 
ATOM 4226 C CA  . LEU D 4 124 ? 122.909 61.097  85.101  1.00 84.03  ? 124 LEU F CA  1 
ATOM 4227 C C   . LEU D 4 124 ? 122.485 59.634  85.034  1.00 85.54  ? 124 LEU F C   1 
ATOM 4228 O O   . LEU D 4 124 ? 123.166 58.732  85.530  1.00 83.91  ? 124 LEU F O   1 
ATOM 4229 C CB  . LEU D 4 124 ? 123.549 61.517  83.779  1.00 84.66  ? 124 LEU F CB  1 
ATOM 4230 C CG  . LEU D 4 124 ? 123.877 63.006  83.657  1.00 84.83  ? 124 LEU F CG  1 
ATOM 4231 C CD1 . LEU D 4 124 ? 124.652 63.275  82.377  1.00 84.61  ? 124 LEU F CD1 1 
ATOM 4232 C CD2 . LEU D 4 124 ? 122.612 63.850  83.707  1.00 82.64  ? 124 LEU F CD2 1 
ATOM 4233 N N   . ARG D 4 125 ? 121.331 59.409  84.406  1.00 88.19  ? 125 ARG F N   1 
ATOM 4234 C CA  . ARG D 4 125 ? 120.761 58.080  84.251  1.00 87.48  ? 125 ARG F CA  1 
ATOM 4235 C C   . ARG D 4 125 ? 120.174 57.964  82.849  1.00 87.86  ? 125 ARG F C   1 
ATOM 4236 O O   . ARG D 4 125 ? 120.194 58.916  82.064  1.00 88.08  ? 125 ARG F O   1 
ATOM 4237 C CB  . ARG D 4 125 ? 119.702 57.810  85.326  1.00 87.37  ? 125 ARG F CB  1 
ATOM 4238 C CG  . ARG D 4 125 ? 118.567 58.819  85.334  1.00 86.00  ? 125 ARG F CG  1 
ATOM 4239 C CD  . ARG D 4 125 ? 117.599 58.588  86.480  1.00 85.91  ? 125 ARG F CD  1 
ATOM 4240 N NE  . ARG D 4 125 ? 118.053 59.213  87.717  1.00 86.50  ? 125 ARG F NE  1 
ATOM 4241 C CZ  . ARG D 4 125 ? 118.685 58.589  88.703  1.00 87.16  ? 125 ARG F CZ  1 
ATOM 4242 N NH1 . ARG D 4 125 ? 118.959 57.295  88.645  1.00 87.29  ? 125 ARG F NH1 1 
ATOM 4243 N NH2 . ARG D 4 125 ? 119.049 59.282  89.778  1.00 86.42  ? 125 ARG F NH2 1 
ATOM 4244 N N   . SER D 4 126 ? 119.644 56.779  82.533  1.00 92.16  ? 126 SER F N   1 
ATOM 4245 C CA  . SER D 4 126 ? 119.048 56.554  81.221  1.00 93.27  ? 126 SER F CA  1 
ATOM 4246 C C   . SER D 4 126 ? 117.736 57.306  81.043  1.00 91.89  ? 126 SER F C   1 
ATOM 4247 O O   . SER D 4 126 ? 117.252 57.426  79.913  1.00 91.43  ? 126 SER F O   1 
ATOM 4248 C CB  . SER D 4 126 ? 118.818 55.060  81.001  1.00 92.72  ? 126 SER F CB  1 
ATOM 4249 O OG  . SER D 4 126 ? 120.024 54.332  81.140  1.00 91.54  ? 126 SER F OG  1 
ATOM 4250 N N   . GLU D 4 127 ? 117.143 57.797  82.129  1.00 90.32  ? 127 GLU F N   1 
ATOM 4251 C CA  . GLU D 4 127 ? 115.894 58.541  82.059  1.00 91.47  ? 127 GLU F CA  1 
ATOM 4252 C C   . GLU D 4 127 ? 116.083 59.982  81.597  1.00 92.74  ? 127 GLU F C   1 
ATOM 4253 O O   . GLU D 4 127 ? 115.086 60.667  81.344  1.00 91.47  ? 127 GLU F O   1 
ATOM 4254 C CB  . GLU D 4 127 ? 115.215 58.526  83.431  1.00 90.77  ? 127 GLU F CB  1 
ATOM 4255 C CG  . GLU D 4 127 ? 113.747 58.909  83.420  1.00 92.15  ? 127 GLU F CG  1 
ATOM 4256 C CD  . GLU D 4 127 ? 113.158 58.980  84.814  1.00 93.19  ? 127 GLU F CD  1 
ATOM 4257 O OE1 . GLU D 4 127 ? 113.739 58.370  85.737  1.00 93.54  ? 127 GLU F OE1 1 
ATOM 4258 O OE2 . GLU D 4 127 ? 112.118 59.648  84.988  1.00 92.78  ? 127 GLU F OE2 1 
ATOM 4259 N N   . ASP D 4 128 ? 117.324 60.456  81.475  1.00 85.97  ? 128 ASP F N   1 
ATOM 4260 C CA  . ASP D 4 128 ? 117.607 61.845  81.138  1.00 83.74  ? 128 ASP F CA  1 
ATOM 4261 C C   . ASP D 4 128 ? 118.144 62.006  79.719  1.00 85.47  ? 128 ASP F C   1 
ATOM 4262 O O   . ASP D 4 128 ? 118.822 62.995  79.426  1.00 87.35  ? 128 ASP F O   1 
ATOM 4263 C CB  . ASP D 4 128 ? 118.595 62.433  82.145  1.00 83.89  ? 128 ASP F CB  1 
ATOM 4264 C CG  . ASP D 4 128 ? 118.161 62.212  83.578  1.00 86.04  ? 128 ASP F CG  1 
ATOM 4265 O OD1 . ASP D 4 128 ? 116.975 61.892  83.797  1.00 87.21  ? 128 ASP F OD1 1 
ATOM 4266 O OD2 . ASP D 4 128 ? 119.005 62.360  84.486  1.00 86.61  ? 128 ASP F OD2 1 
ATOM 4267 N N   . THR D 4 129 ? 117.854 61.058  78.831  1.00 84.90  ? 129 THR F N   1 
ATOM 4268 C CA  . THR D 4 129 ? 118.294 61.128  77.439  1.00 85.96  ? 129 THR F CA  1 
ATOM 4269 C C   . THR D 4 129 ? 117.250 61.912  76.654  1.00 84.96  ? 129 THR F C   1 
ATOM 4270 O O   . THR D 4 129 ? 116.210 61.370  76.272  1.00 84.36  ? 129 THR F O   1 
ATOM 4271 C CB  . THR D 4 129 ? 118.485 59.731  76.861  1.00 86.00  ? 129 THR F CB  1 
ATOM 4272 O OG1 . THR D 4 129 ? 117.208 59.102  76.695  1.00 85.96  ? 129 THR F OG1 1 
ATOM 4273 C CG2 . THR D 4 129 ? 119.341 58.886  77.787  1.00 86.17  ? 129 THR F CG2 1 
ATOM 4274 N N   . ALA D 4 130 ? 117.524 63.190  76.408  1.00 73.79  ? 130 ALA F N   1 
ATOM 4275 C CA  . ALA D 4 130 ? 116.547 64.061  75.771  1.00 73.31  ? 130 ALA F CA  1 
ATOM 4276 C C   . ALA D 4 130 ? 117.252 65.292  75.219  1.00 71.96  ? 130 ALA F C   1 
ATOM 4277 O O   . ALA D 4 130 ? 118.394 65.591  75.573  1.00 73.72  ? 130 ALA F O   1 
ATOM 4278 C CB  . ALA D 4 130 ? 115.448 64.464  76.756  1.00 74.21  ? 130 ALA F CB  1 
ATOM 4279 N N   . MET D 4 131 ? 116.542 66.007  74.349  1.00 63.72  ? 131 MET F N   1 
ATOM 4280 C CA  . MET D 4 131 ? 117.018 67.265  73.790  1.00 63.77  ? 131 MET F CA  1 
ATOM 4281 C C   . MET D 4 131 ? 116.468 68.422  74.614  1.00 63.97  ? 131 MET F C   1 
ATOM 4282 O O   . MET D 4 131 ? 115.259 68.504  74.851  1.00 65.20  ? 131 MET F O   1 
ATOM 4283 C CB  . MET D 4 131 ? 116.586 67.396  72.330  1.00 63.33  ? 131 MET F CB  1 
ATOM 4284 C CG  . MET D 4 131 ? 117.009 68.689  71.663  1.00 61.48  ? 131 MET F CG  1 
ATOM 4285 S SD  . MET D 4 131 ? 117.025 68.561  69.866  1.00 69.37  ? 131 MET F SD  1 
ATOM 4286 C CE  . MET D 4 131 ? 115.411 67.851  69.556  1.00 65.68  ? 131 MET F CE  1 
ATOM 4287 N N   . TYR D 4 132 ? 117.355 69.316  75.039  1.00 55.97  ? 132 TYR F N   1 
ATOM 4288 C CA  . TYR D 4 132 ? 117.022 70.363  75.995  1.00 54.27  ? 132 TYR F CA  1 
ATOM 4289 C C   . TYR D 4 132 ? 116.849 71.696  75.281  1.00 53.12  ? 132 TYR F C   1 
ATOM 4290 O O   . TYR D 4 132 ? 117.717 72.107  74.504  1.00 51.82  ? 132 TYR F O   1 
ATOM 4291 C CB  . TYR D 4 132 ? 118.108 70.475  77.066  1.00 53.54  ? 132 TYR F CB  1 
ATOM 4292 C CG  . TYR D 4 132 ? 118.207 69.261  77.959  1.00 55.35  ? 132 TYR F CG  1 
ATOM 4293 C CD1 . TYR D 4 132 ? 118.913 68.135  77.560  1.00 55.19  ? 132 TYR F CD1 1 
ATOM 4294 C CD2 . TYR D 4 132 ? 117.591 69.240  79.202  1.00 57.11  ? 132 TYR F CD2 1 
ATOM 4295 C CE1 . TYR D 4 132 ? 119.003 67.021  78.374  1.00 56.14  ? 132 TYR F CE1 1 
ATOM 4296 C CE2 . TYR D 4 132 ? 117.676 68.132  80.023  1.00 57.81  ? 132 TYR F CE2 1 
ATOM 4297 C CZ  . TYR D 4 132 ? 118.383 67.027  79.604  1.00 54.85  ? 132 TYR F CZ  1 
ATOM 4298 O OH  . TYR D 4 132 ? 118.470 65.923  80.418  1.00 56.45  ? 132 TYR F OH  1 
ATOM 4299 N N   . TYR D 4 133 ? 115.735 72.370  75.557  1.00 47.71  ? 133 TYR F N   1 
ATOM 4300 C CA  . TYR D 4 133 ? 115.420 73.669  74.984  1.00 46.07  ? 133 TYR F CA  1 
ATOM 4301 C C   . TYR D 4 133 ? 115.518 74.755  76.047  1.00 44.90  ? 133 TYR F C   1 
ATOM 4302 O O   . TYR D 4 133 ? 115.378 74.492  77.243  1.00 36.37  ? 133 TYR F O   1 
ATOM 4303 C CB  . TYR D 4 133 ? 114.013 73.685  74.382  1.00 45.01  ? 133 TYR F CB  1 
ATOM 4304 C CG  . TYR D 4 133 ? 113.847 72.809  73.168  1.00 46.68  ? 133 TYR F CG  1 
ATOM 4305 C CD1 . TYR D 4 133 ? 114.353 73.195  71.937  1.00 46.74  ? 133 TYR F CD1 1 
ATOM 4306 C CD2 . TYR D 4 133 ? 113.171 71.601  73.250  1.00 44.87  ? 133 TYR F CD2 1 
ATOM 4307 C CE1 . TYR D 4 133 ? 114.200 72.399  70.824  1.00 45.75  ? 133 TYR F CE1 1 
ATOM 4308 C CE2 . TYR D 4 133 ? 113.012 70.799  72.141  1.00 47.30  ? 133 TYR F CE2 1 
ATOM 4309 C CZ  . TYR D 4 133 ? 113.528 71.203  70.931  1.00 46.41  ? 133 TYR F CZ  1 
ATOM 4310 O OH  . TYR D 4 133 ? 113.370 70.407  69.824  1.00 48.00  ? 133 TYR F OH  1 
ATOM 4311 N N   . CYS D 4 134 ? 115.758 75.981  75.593  1.00 51.08  ? 134 CYS F N   1 
ATOM 4312 C CA  . CYS D 4 134 ? 115.778 77.159  76.448  1.00 44.87  ? 134 CYS F CA  1 
ATOM 4313 C C   . CYS D 4 134 ? 114.679 78.106  75.994  1.00 45.93  ? 134 CYS F C   1 
ATOM 4314 O O   . CYS D 4 134 ? 114.506 78.328  74.791  1.00 45.55  ? 134 CYS F O   1 
ATOM 4315 C CB  . CYS D 4 134 ? 117.137 77.855  76.399  1.00 41.38  ? 134 CYS F CB  1 
ATOM 4316 S SG  . CYS D 4 134 ? 117.356 79.110  77.668  1.00 45.75  ? 134 CYS F SG  1 
ATOM 4317 N N   . VAL D 4 135 ? 113.933 78.653  76.954  1.00 36.61  ? 135 VAL F N   1 
ATOM 4318 C CA  . VAL D 4 135 ? 112.789 79.511  76.681  1.00 31.52  ? 135 VAL F CA  1 
ATOM 4319 C C   . VAL D 4 135 ? 112.877 80.748  77.563  1.00 27.83  ? 135 VAL F C   1 
ATOM 4320 O O   . VAL D 4 135 ? 113.409 80.699  78.675  1.00 40.33  ? 135 VAL F O   1 
ATOM 4321 C CB  . VAL D 4 135 ? 111.460 78.768  76.920  1.00 32.43  ? 135 VAL F CB  1 
ATOM 4322 C CG1 . VAL D 4 135 ? 110.283 79.637  76.518  1.00 32.20  ? 135 VAL F CG1 1 
ATOM 4323 C CG2 . VAL D 4 135 ? 111.449 77.448  76.169  1.00 30.88  ? 135 VAL F CG2 1 
ATOM 4324 N N   . ARG D 4 136 ? 112.346 81.862  77.060  1.00 28.86  ? 136 ARG F N   1 
ATOM 4325 C CA  . ARG D 4 136 ? 112.341 83.132  77.773  1.00 28.76  ? 136 ARG F CA  1 
ATOM 4326 C C   . ARG D 4 136 ? 110.907 83.550  78.078  1.00 32.30  ? 136 ARG F C   1 
ATOM 4327 O O   . ARG D 4 136 ? 109.974 83.194  77.353  1.00 28.86  ? 136 ARG F O   1 
ATOM 4328 C CB  . ARG D 4 136 ? 113.042 84.233  76.964  1.00 31.70  ? 136 ARG F CB  1 
ATOM 4329 C CG  . ARG D 4 136 ? 112.351 84.606  75.655  1.00 33.34  ? 136 ARG F CG  1 
ATOM 4330 C CD  . ARG D 4 136 ? 112.993 85.822  75.005  1.00 27.81  ? 136 ARG F CD  1 
ATOM 4331 N NE  . ARG D 4 136 ? 112.097 86.471  74.055  1.00 28.35  ? 136 ARG F NE  1 
ATOM 4332 C CZ  . ARG D 4 136 ? 112.312 87.658  73.504  1.00 30.82  ? 136 ARG F CZ  1 
ATOM 4333 N NH1 . ARG D 4 136 ? 113.397 88.362  73.776  1.00 34.26  ? 136 ARG F NH1 1 
ATOM 4334 N NH2 . ARG D 4 136 ? 111.411 88.154  72.663  1.00 24.86  ? 136 ARG F NH2 1 
ATOM 4335 N N   . SER D 4 137 ? 110.739 84.307  79.162  1.00 29.54  ? 137 SER F N   1 
ATOM 4336 C CA  . SER D 4 137 ? 109.424 84.777  79.574  1.00 23.31  ? 137 SER F CA  1 
ATOM 4337 C C   . SER D 4 137 ? 109.570 86.068  80.364  1.00 22.99  ? 137 SER F C   1 
ATOM 4338 O O   . SER D 4 137 ? 110.508 86.220  81.149  1.00 39.53  ? 137 SER F O   1 
ATOM 4339 C CB  . SER D 4 137 ? 108.703 83.728  80.419  1.00 23.16  ? 137 SER F CB  1 
ATOM 4340 O OG  . SER D 4 137 ? 108.528 82.530  79.692  1.00 30.12  ? 137 SER F OG  1 
ATOM 4341 N N   . ILE D 4 138 ? 108.633 86.988  80.161  1.00 19.36  ? 138 ILE F N   1 
ATOM 4342 C CA  . ILE D 4 138 ? 108.625 88.278  80.840  1.00 25.65  ? 138 ILE F CA  1 
ATOM 4343 C C   . ILE D 4 138 ? 107.224 88.510  81.390  1.00 26.27  ? 138 ILE F C   1 
ATOM 4344 O O   . ILE D 4 138 ? 106.231 88.259  80.701  1.00 21.73  ? 138 ILE F O   1 
ATOM 4345 C CB  . ILE D 4 138 ? 109.062 89.416  79.887  1.00 31.49  ? 138 ILE F CB  1 
ATOM 4346 C CG1 . ILE D 4 138 ? 109.344 90.699  80.659  1.00 24.23  ? 138 ILE F CG1 1 
ATOM 4347 C CG2 . ILE D 4 138 ? 108.015 89.669  78.820  1.00 27.40  ? 138 ILE F CG2 1 
ATOM 4348 C CD1 . ILE D 4 138 ? 110.168 91.683  79.885  1.00 17.59  ? 138 ILE F CD1 1 
ATOM 4349 N N   . TYR D 4 139 ? 107.144 88.977  82.638  1.00 25.54  ? 139 TYR F N   1 
ATOM 4350 C CA  . TYR D 4 139 ? 105.882 89.048  83.372  1.00 20.57  ? 139 TYR F CA  1 
ATOM 4351 C C   . TYR D 4 139 ? 105.620 90.479  83.824  1.00 25.09  ? 139 TYR F C   1 
ATOM 4352 O O   . TYR D 4 139 ? 106.281 90.976  84.741  1.00 18.48  ? 139 TYR F O   1 
ATOM 4353 C CB  . TYR D 4 139 ? 105.892 88.100  84.574  1.00 13.67  ? 139 TYR F CB  1 
ATOM 4354 C CG  . TYR D 4 139 ? 106.216 86.670  84.219  1.00 16.71  ? 139 TYR F CG  1 
ATOM 4355 C CD1 . TYR D 4 139 ? 105.230 85.799  83.786  1.00 13.00  ? 139 TYR F CD1 1 
ATOM 4356 C CD2 . TYR D 4 139 ? 107.513 86.193  84.316  1.00 27.25  ? 139 TYR F CD2 1 
ATOM 4357 C CE1 . TYR D 4 139 ? 105.529 84.497  83.455  1.00 13.25  ? 139 TYR F CE1 1 
ATOM 4358 C CE2 . TYR D 4 139 ? 107.821 84.897  83.989  1.00 25.85  ? 139 TYR F CE2 1 
ATOM 4359 C CZ  . TYR D 4 139 ? 106.830 84.053  83.560  1.00 26.65  ? 139 TYR F CZ  1 
ATOM 4360 O OH  . TYR D 4 139 ? 107.154 82.760  83.237  1.00 28.01  ? 139 TYR F OH  1 
ATOM 4361 N N   . TYR D 4 140 ? 104.669 91.136  83.166  1.00 23.75  ? 140 TYR F N   1 
ATOM 4362 C CA  . TYR D 4 140 ? 104.034 92.349  83.669  1.00 11.90  ? 140 TYR F CA  1 
ATOM 4363 C C   . TYR D 4 140 ? 102.595 92.347  83.172  1.00 15.68  ? 140 TYR F C   1 
ATOM 4364 O O   . TYR D 4 140 ? 102.137 91.377  82.563  1.00 22.72  ? 140 TYR F O   1 
ATOM 4365 C CB  . TYR D 4 140 ? 104.798 93.613  83.251  1.00 16.75  ? 140 TYR F CB  1 
ATOM 4366 C CG  . TYR D 4 140 ? 105.149 93.721  81.786  1.00 24.68  ? 140 TYR F CG  1 
ATOM 4367 C CD1 . TYR D 4 140 ? 104.235 94.208  80.866  1.00 17.97  ? 140 TYR F CD1 1 
ATOM 4368 C CD2 . TYR D 4 140 ? 106.410 93.364  81.332  1.00 18.03  ? 140 TYR F CD2 1 
ATOM 4369 C CE1 . TYR D 4 140 ? 104.558 94.316  79.534  1.00 12.35  ? 140 TYR F CE1 1 
ATOM 4370 C CE2 . TYR D 4 140 ? 106.740 93.471  80.005  1.00 24.36  ? 140 TYR F CE2 1 
ATOM 4371 C CZ  . TYR D 4 140 ? 105.812 93.948  79.109  1.00 18.58  ? 140 TYR F CZ  1 
ATOM 4372 O OH  . TYR D 4 140 ? 106.142 94.055  77.779  1.00 24.85  ? 140 TYR F OH  1 
ATOM 4373 N N   . TYR D 4 141 ? 101.870 93.430  83.433  1.00 16.95  ? 141 TYR F N   1 
ATOM 4374 C CA  . TYR D 4 141 ? 100.461 93.484  83.062  1.00 17.84  ? 141 TYR F CA  1 
ATOM 4375 C C   . TYR D 4 141 ? 100.331 93.547  81.544  1.00 20.33  ? 141 TYR F C   1 
ATOM 4376 O O   . TYR D 4 141 ? 100.589 94.588  80.933  1.00 20.31  ? 141 TYR F O   1 
ATOM 4377 C CB  . TYR D 4 141 ? 99.773  94.681  83.712  1.00 11.07  ? 141 TYR F CB  1 
ATOM 4378 C CG  . TYR D 4 141 ? 98.345  94.817  83.256  1.00 12.29  ? 141 TYR F CG  1 
ATOM 4379 C CD1 . TYR D 4 141 ? 97.379  93.921  83.677  1.00 15.20  ? 141 TYR F CD1 1 
ATOM 4380 C CD2 . TYR D 4 141 ? 97.968  95.818  82.379  1.00 13.79  ? 141 TYR F CD2 1 
ATOM 4381 C CE1 . TYR D 4 141 ? 96.079  94.027  83.246  1.00 17.02  ? 141 TYR F CE1 1 
ATOM 4382 C CE2 . TYR D 4 141 ? 96.671  95.933  81.945  1.00 9.88   ? 141 TYR F CE2 1 
ATOM 4383 C CZ  . TYR D 4 141 ? 95.732  95.035  82.380  1.00 19.36  ? 141 TYR F CZ  1 
ATOM 4384 O OH  . TYR D 4 141 ? 94.433  95.148  81.950  1.00 24.99  ? 141 TYR F OH  1 
ATOM 4385 N N   . GLY D 4 142 ? 99.927  92.434  80.935  1.00 7.89   ? 142 GLY F N   1 
ATOM 4386 C CA  . GLY D 4 142 ? 99.660  92.380  79.514  1.00 17.04  ? 142 GLY F CA  1 
ATOM 4387 C C   . GLY D 4 142 ? 100.754 91.770  78.664  1.00 22.41  ? 142 GLY F C   1 
ATOM 4388 O O   . GLY D 4 142 ? 100.609 91.737  77.437  1.00 25.29  ? 142 GLY F O   1 
ATOM 4389 N N   . SER D 4 143 ? 101.835 91.284  79.268  1.00 23.75  ? 143 SER F N   1 
ATOM 4390 C CA  . SER D 4 143 ? 102.931 90.698  78.515  1.00 22.69  ? 143 SER F CA  1 
ATOM 4391 C C   . SER D 4 143 ? 102.573 89.290  78.041  1.00 33.35  ? 143 SER F C   1 
ATOM 4392 O O   . SER D 4 143 ? 101.559 88.708  78.434  1.00 44.42  ? 143 SER F O   1 
ATOM 4393 C CB  . SER D 4 143 ? 104.196 90.656  79.364  1.00 21.07  ? 143 SER F CB  1 
ATOM 4394 O OG  . SER D 4 143 ? 104.052 89.742  80.430  1.00 18.83  ? 143 SER F OG  1 
ATOM 4395 N N   . SER D 4 144 ? 103.422 88.747  77.176  1.00 26.97  ? 144 SER F N   1 
ATOM 4396 C CA  . SER D 4 144 ? 103.272 87.384  76.668  1.00 26.67  ? 144 SER F CA  1 
ATOM 4397 C C   . SER D 4 144 ? 104.494 86.564  77.058  1.00 33.49  ? 144 SER F C   1 
ATOM 4398 O O   . SER D 4 144 ? 105.571 86.749  76.461  1.00 28.64  ? 144 SER F O   1 
ATOM 4399 C CB  . SER D 4 144 ? 103.100 87.385  75.151  1.00 33.22  ? 144 SER F CB  1 
ATOM 4400 O OG  . SER D 4 144 ? 104.291 87.785  74.505  1.00 35.73  ? 144 SER F OG  1 
ATOM 4401 N N   . PRO D 4 145 ? 104.407 85.675  78.043  1.00 39.87  ? 145 PRO F N   1 
ATOM 4402 C CA  . PRO D 4 145 ? 105.537 84.793  78.344  1.00 34.95  ? 145 PRO F CA  1 
ATOM 4403 C C   . PRO D 4 145 ? 105.609 83.623  77.367  1.00 31.63  ? 145 PRO F C   1 
ATOM 4404 O O   . PRO D 4 145 ? 104.693 83.363  76.589  1.00 30.79  ? 145 PRO F O   1 
ATOM 4405 C CB  . PRO D 4 145 ? 105.247 84.321  79.773  1.00 27.90  ? 145 PRO F CB  1 
ATOM 4406 C CG  . PRO D 4 145 ? 103.794 84.437  79.927  1.00 31.43  ? 145 PRO F CG  1 
ATOM 4407 C CD  . PRO D 4 145 ? 103.348 85.577  79.064  1.00 30.57  ? 145 PRO F CD  1 
ATOM 4408 N N   . PHE D 4 146 ? 106.737 82.914  77.429  1.00 33.79  ? 146 PHE F N   1 
ATOM 4409 C CA  . PHE D 4 146 ? 107.015 81.779  76.544  1.00 32.31  ? 146 PHE F CA  1 
ATOM 4410 C C   . PHE D 4 146 ? 106.952 82.199  75.074  1.00 32.72  ? 146 PHE F C   1 
ATOM 4411 O O   . PHE D 4 146 ? 106.300 81.564  74.244  1.00 33.74  ? 146 PHE F O   1 
ATOM 4412 C CB  . PHE D 4 146 ? 106.064 80.611  76.832  1.00 34.04  ? 146 PHE F CB  1 
ATOM 4413 C CG  . PHE D 4 146 ? 106.601 79.627  77.836  1.00 40.12  ? 146 PHE F CG  1 
ATOM 4414 C CD1 . PHE D 4 146 ? 106.724 79.971  79.171  1.00 36.65  ? 146 PHE F CD1 1 
ATOM 4415 C CD2 . PHE D 4 146 ? 106.979 78.354  77.443  1.00 34.75  ? 146 PHE F CD2 1 
ATOM 4416 C CE1 . PHE D 4 146 ? 107.217 79.067  80.090  1.00 32.81  ? 146 PHE F CE1 1 
ATOM 4417 C CE2 . PHE D 4 146 ? 107.471 77.446  78.361  1.00 34.40  ? 146 PHE F CE2 1 
ATOM 4418 C CZ  . PHE D 4 146 ? 107.589 77.804  79.683  1.00 34.46  ? 146 PHE F CZ  1 
ATOM 4419 N N   . ASP D 4 147 ? 107.668 83.278  74.752  1.00 35.83  ? 147 ASP F N   1 
ATOM 4420 C CA  . ASP D 4 147 ? 107.675 83.801  73.390  1.00 31.32  ? 147 ASP F CA  1 
ATOM 4421 C C   . ASP D 4 147 ? 108.624 83.020  72.490  1.00 44.32  ? 147 ASP F C   1 
ATOM 4422 O O   . ASP D 4 147 ? 108.204 82.420  71.496  1.00 44.99  ? 147 ASP F O   1 
ATOM 4423 C CB  . ASP D 4 147 ? 108.080 85.276  73.396  1.00 29.23  ? 147 ASP F CB  1 
ATOM 4424 C CG  . ASP D 4 147 ? 106.953 86.191  73.788  1.00 43.83  ? 147 ASP F CG  1 
ATOM 4425 O OD1 . ASP D 4 147 ? 105.787 85.882  73.467  1.00 47.10  ? 147 ASP F OD1 1 
ATOM 4426 O OD2 . ASP D 4 147 ? 107.240 87.232  74.414  1.00 44.12  ? 147 ASP F OD2 1 
ATOM 4427 N N   . PHE D 4 148 ? 109.911 83.016  72.828  1.00 40.74  ? 148 PHE F N   1 
ATOM 4428 C CA  . PHE D 4 148 ? 110.962 82.566  71.930  1.00 33.21  ? 148 PHE F CA  1 
ATOM 4429 C C   . PHE D 4 148 ? 111.627 81.320  72.495  1.00 38.37  ? 148 PHE F C   1 
ATOM 4430 O O   . PHE D 4 148 ? 112.017 81.294  73.666  1.00 39.28  ? 148 PHE F O   1 
ATOM 4431 C CB  . PHE D 4 148 ? 111.993 83.678  71.721  1.00 39.65  ? 148 PHE F CB  1 
ATOM 4432 C CG  . PHE D 4 148 ? 112.950 83.415  70.598  1.00 42.49  ? 148 PHE F CG  1 
ATOM 4433 C CD1 . PHE D 4 148 ? 112.503 83.354  69.291  1.00 36.94  ? 148 PHE F CD1 1 
ATOM 4434 C CD2 . PHE D 4 148 ? 114.298 83.236  70.848  1.00 41.69  ? 148 PHE F CD2 1 
ATOM 4435 C CE1 . PHE D 4 148 ? 113.379 83.113  68.259  1.00 37.67  ? 148 PHE F CE1 1 
ATOM 4436 C CE2 . PHE D 4 148 ? 115.178 82.995  69.817  1.00 41.52  ? 148 PHE F CE2 1 
ATOM 4437 C CZ  . PHE D 4 148 ? 114.718 82.935  68.523  1.00 40.05  ? 148 PHE F CZ  1 
ATOM 4438 N N   . TRP D 4 149 ? 111.756 80.296  71.655  1.00 44.57  ? 149 TRP F N   1 
ATOM 4439 C CA  . TRP D 4 149 ? 112.399 79.039  71.999  1.00 38.43  ? 149 TRP F CA  1 
ATOM 4440 C C   . TRP D 4 149 ? 113.715 78.909  71.243  1.00 45.33  ? 149 TRP F C   1 
ATOM 4441 O O   . TRP D 4 149 ? 113.838 79.353  70.099  1.00 45.73  ? 149 TRP F O   1 
ATOM 4442 C CB  . TRP D 4 149 ? 111.505 77.843  71.659  1.00 36.91  ? 149 TRP F CB  1 
ATOM 4443 C CG  . TRP D 4 149 ? 110.285 77.707  72.514  1.00 42.49  ? 149 TRP F CG  1 
ATOM 4444 C CD1 . TRP D 4 149 ? 109.325 78.649  72.733  1.00 45.49  ? 149 TRP F CD1 1 
ATOM 4445 C CD2 . TRP D 4 149 ? 109.881 76.544  73.248  1.00 47.60  ? 149 TRP F CD2 1 
ATOM 4446 N NE1 . TRP D 4 149 ? 108.354 78.149  73.565  1.00 46.05  ? 149 TRP F NE1 1 
ATOM 4447 C CE2 . TRP D 4 149 ? 108.671 76.859  73.895  1.00 45.41  ? 149 TRP F CE2 1 
ATOM 4448 C CE3 . TRP D 4 149 ? 110.427 75.269  73.426  1.00 47.30  ? 149 TRP F CE3 1 
ATOM 4449 C CZ2 . TRP D 4 149 ? 107.999 75.946  74.705  1.00 40.74  ? 149 TRP F CZ2 1 
ATOM 4450 C CZ3 . TRP D 4 149 ? 109.758 74.368  74.230  1.00 44.50  ? 149 TRP F CZ3 1 
ATOM 4451 C CH2 . TRP D 4 149 ? 108.558 74.708  74.857  1.00 39.01  ? 149 TRP F CH2 1 
ATOM 4452 N N   . GLY D 4 150 ? 114.700 78.291  71.895  1.00 51.28  ? 150 GLY F N   1 
ATOM 4453 C CA  . GLY D 4 150 ? 115.987 78.052  71.278  1.00 49.06  ? 150 GLY F CA  1 
ATOM 4454 C C   . GLY D 4 150 ? 116.027 76.743  70.509  1.00 50.23  ? 150 GLY F C   1 
ATOM 4455 O O   . GLY D 4 150 ? 115.042 76.015  70.396  1.00 50.85  ? 150 GLY F O   1 
ATOM 4456 N N   . GLN D 4 151 ? 117.207 76.449  69.970  1.00 60.65  ? 151 GLN F N   1 
ATOM 4457 C CA  . GLN D 4 151 ? 117.461 75.209  69.247  1.00 61.30  ? 151 GLN F CA  1 
ATOM 4458 C C   . GLN D 4 151 ? 118.179 74.242  70.181  1.00 63.13  ? 151 GLN F C   1 
ATOM 4459 O O   . GLN D 4 151 ? 119.267 74.547  70.681  1.00 61.20  ? 151 GLN F O   1 
ATOM 4460 C CB  . GLN D 4 151 ? 118.291 75.472  67.991  1.00 61.07  ? 151 GLN F CB  1 
ATOM 4461 C CG  . GLN D 4 151 ? 117.586 76.332  66.954  1.00 59.52  ? 151 GLN F CG  1 
ATOM 4462 C CD  . GLN D 4 151 ? 116.419 75.616  66.308  1.00 62.08  ? 151 GLN F CD  1 
ATOM 4463 O OE1 . GLN D 4 151 ? 116.187 74.434  66.557  1.00 63.53  ? 151 GLN F OE1 1 
ATOM 4464 N NE2 . GLN D 4 151 ? 115.674 76.331  65.472  1.00 61.45  ? 151 GLN F NE2 1 
ATOM 4465 N N   . GLY D 4 152 ? 117.576 73.081  70.407  1.00 65.11  ? 152 GLY F N   1 
ATOM 4466 C CA  . GLY D 4 152 ? 118.031 72.198  71.459  1.00 61.57  ? 152 GLY F CA  1 
ATOM 4467 C C   . GLY D 4 152 ? 119.330 71.489  71.135  1.00 66.78  ? 152 GLY F C   1 
ATOM 4468 O O   . GLY D 4 152 ? 119.820 71.474  70.005  1.00 66.45  ? 152 GLY F O   1 
ATOM 4469 N N   . THR D 4 153 ? 119.900 70.889  72.177  1.00 69.92  ? 153 THR F N   1 
ATOM 4470 C CA  . THR D 4 153 ? 121.104 70.075  72.082  1.00 69.07  ? 153 THR F CA  1 
ATOM 4471 C C   . THR D 4 153 ? 120.796 68.694  72.640  1.00 69.94  ? 153 THR F C   1 
ATOM 4472 O O   . THR D 4 153 ? 120.227 68.575  73.730  1.00 69.62  ? 153 THR F O   1 
ATOM 4473 C CB  . THR D 4 153 ? 122.266 70.704  72.852  1.00 69.48  ? 153 THR F CB  1 
ATOM 4474 O OG1 . THR D 4 153 ? 121.858 70.982  74.197  1.00 65.51  ? 153 THR F OG1 1 
ATOM 4475 C CG2 . THR D 4 153 ? 122.715 71.990  72.181  1.00 69.60  ? 153 THR F CG2 1 
ATOM 4476 N N   . THR D 4 154 ? 121.173 67.657  71.898  1.00 75.43  ? 154 THR F N   1 
ATOM 4477 C CA  . THR D 4 154 ? 120.847 66.293  72.284  1.00 75.02  ? 154 THR F CA  1 
ATOM 4478 C C   . THR D 4 154 ? 121.866 65.776  73.289  1.00 76.23  ? 154 THR F C   1 
ATOM 4479 O O   . THR D 4 154 ? 123.076 65.915  73.087  1.00 77.00  ? 154 THR F O   1 
ATOM 4480 C CB  . THR D 4 154 ? 120.812 65.382  71.057  1.00 75.78  ? 154 THR F CB  1 
ATOM 4481 O OG1 . THR D 4 154 ? 119.935 65.934  70.068  1.00 76.10  ? 154 THR F OG1 1 
ATOM 4482 C CG2 . THR D 4 154 ? 120.327 63.990  71.439  1.00 75.53  ? 154 THR F CG2 1 
ATOM 4483 N N   . LEU D 4 155 ? 121.375 65.182  74.375  1.00 82.02  ? 155 LEU F N   1 
ATOM 4484 C CA  . LEU D 4 155 ? 122.215 64.535  75.374  1.00 82.44  ? 155 LEU F CA  1 
ATOM 4485 C C   . LEU D 4 155 ? 121.812 63.072  75.473  1.00 83.06  ? 155 LEU F C   1 
ATOM 4486 O O   . LEU D 4 155 ? 120.621 62.759  75.581  1.00 83.86  ? 155 LEU F O   1 
ATOM 4487 C CB  . LEU D 4 155 ? 122.085 65.220  76.739  1.00 81.64  ? 155 LEU F CB  1 
ATOM 4488 C CG  . LEU D 4 155 ? 122.858 64.587  77.898  1.00 81.48  ? 155 LEU F CG  1 
ATOM 4489 C CD1 . LEU D 4 155 ? 124.359 64.758  77.720  1.00 83.30  ? 155 LEU F CD1 1 
ATOM 4490 C CD2 . LEU D 4 155 ? 122.403 65.179  79.220  1.00 80.54  ? 155 LEU F CD2 1 
ATOM 4491 N N   . THR D 4 156 ? 122.798 62.182  75.432  1.00 89.56  ? 156 THR F N   1 
ATOM 4492 C CA  . THR D 4 156 ? 122.562 60.747  75.478  1.00 90.57  ? 156 THR F CA  1 
ATOM 4493 C C   . THR D 4 156 ? 123.316 60.135  76.648  1.00 90.40  ? 156 THR F C   1 
ATOM 4494 O O   . THR D 4 156 ? 124.443 60.537  76.957  1.00 90.84  ? 156 THR F O   1 
ATOM 4495 C CB  . THR D 4 156 ? 122.991 60.065  74.176  1.00 90.55  ? 156 THR F CB  1 
ATOM 4496 O OG1 . THR D 4 156 ? 124.333 60.442  73.850  1.00 89.22  ? 156 THR F OG1 1 
ATOM 4497 C CG2 . THR D 4 156 ? 122.064 60.461  73.042  1.00 90.32  ? 156 THR F CG2 1 
ATOM 4498 N N   . VAL D 4 157 ? 122.677 59.165  77.295  1.00 94.16  ? 157 VAL F N   1 
ATOM 4499 C CA  . VAL D 4 157 ? 123.227 58.468  78.450  1.00 95.10  ? 157 VAL F CA  1 
ATOM 4500 C C   . VAL D 4 157 ? 123.077 56.974  78.214  1.00 96.09  ? 157 VAL F C   1 
ATOM 4501 O O   . VAL D 4 157 ? 121.975 56.496  77.919  1.00 96.40  ? 157 VAL F O   1 
ATOM 4502 C CB  . VAL D 4 157 ? 122.517 58.877  79.752  1.00 94.41  ? 157 VAL F CB  1 
ATOM 4503 C CG1 . VAL D 4 157 ? 123.083 58.102  80.941  1.00 95.23  ? 157 VAL F CG1 1 
ATOM 4504 C CG2 . VAL D 4 157 ? 122.632 60.379  79.957  1.00 92.99  ? 157 VAL F CG2 1 
ATOM 4505 N N   . SER D 4 158 ? 124.177 56.239  78.354  1.00 98.80  ? 158 SER F N   1 
ATOM 4506 C CA  . SER D 4 158 ? 124.154 54.790  78.187  1.00 99.23  ? 158 SER F CA  1 
ATOM 4507 C C   . SER D 4 158 ? 123.729 54.120  79.489  1.00 98.84  ? 158 SER F C   1 
ATOM 4508 O O   . SER D 4 158 ? 123.184 53.016  79.484  1.00 98.21  ? 158 SER F O   1 
ATOM 4509 C CB  . SER D 4 158 ? 125.528 54.276  77.745  1.00 98.49  ? 158 SER F CB  1 
ATOM 4510 O OG  . SER D 4 158 ? 126.566 54.882  78.495  1.00 98.25  ? 158 SER F OG  1 
ATOM 4511 N N   . SER D 4 174 ? 98.471  67.609  93.833  1.00 64.75  ? 174 SER F N   1 
ATOM 4512 C CA  . SER D 4 174 ? 99.920  67.749  93.758  1.00 65.56  ? 174 SER F CA  1 
ATOM 4513 C C   . SER D 4 174 ? 100.358 68.388  92.444  1.00 63.60  ? 174 SER F C   1 
ATOM 4514 O O   . SER D 4 174 ? 100.902 69.490  92.431  1.00 61.27  ? 174 SER F O   1 
ATOM 4515 C CB  . SER D 4 174 ? 100.597 66.385  93.913  1.00 65.57  ? 174 SER F CB  1 
ATOM 4516 O OG  . SER D 4 174 ? 100.055 65.435  93.012  1.00 62.22  ? 174 SER F OG  1 
ATOM 4517 N N   . ASP D 4 175 ? 100.140 67.673  91.344  1.00 63.15  ? 175 ASP F N   1 
ATOM 4518 C CA  . ASP D 4 175 ? 100.503 68.129  90.012  1.00 64.49  ? 175 ASP F CA  1 
ATOM 4519 C C   . ASP D 4 175 ? 99.267  68.107  89.125  1.00 65.29  ? 175 ASP F C   1 
ATOM 4520 O O   . ASP D 4 175 ? 98.495  67.144  89.146  1.00 65.43  ? 175 ASP F O   1 
ATOM 4521 C CB  . ASP D 4 175 ? 101.605 67.250  89.404  1.00 64.22  ? 175 ASP F CB  1 
ATOM 4522 C CG  . ASP D 4 175 ? 102.953 67.453  90.072  1.00 65.63  ? 175 ASP F CG  1 
ATOM 4523 O OD1 . ASP D 4 175 ? 102.999 68.084  91.148  1.00 63.62  ? 175 ASP F OD1 1 
ATOM 4524 O OD2 . ASP D 4 175 ? 103.969 66.983  89.518  1.00 66.69  ? 175 ASP F OD2 1 
ATOM 4525 N N   . ILE D 4 176 ? 99.082  69.172  88.355  1.00 61.05  ? 176 ILE F N   1 
ATOM 4526 C CA  . ILE D 4 176 ? 97.931  69.283  87.466  1.00 58.83  ? 176 ILE F CA  1 
ATOM 4527 C C   . ILE D 4 176 ? 98.180  68.422  86.235  1.00 59.72  ? 176 ILE F C   1 
ATOM 4528 O O   . ILE D 4 176 ? 99.239  68.510  85.603  1.00 59.95  ? 176 ILE F O   1 
ATOM 4529 C CB  . ILE D 4 176 ? 97.677  70.752  87.088  1.00 55.38  ? 176 ILE F CB  1 
ATOM 4530 C CG1 . ILE D 4 176 ? 97.336  71.560  88.344  1.00 57.62  ? 176 ILE F CG1 1 
ATOM 4531 C CG2 . ILE D 4 176 ? 96.558  70.859  86.055  1.00 57.82  ? 176 ILE F CG2 1 
ATOM 4532 C CD1 . ILE D 4 176 ? 97.332  73.053  88.142  1.00 56.29  ? 176 ILE F CD1 1 
ATOM 4533 N N   . VAL D 4 177 ? 97.207  67.583  85.895  1.00 62.38  ? 177 VAL F N   1 
ATOM 4534 C CA  . VAL D 4 177 ? 97.320  66.630  84.799  1.00 64.08  ? 177 VAL F CA  1 
ATOM 4535 C C   . VAL D 4 177 ? 96.415  67.081  83.663  1.00 64.02  ? 177 VAL F C   1 
ATOM 4536 O O   . VAL D 4 177 ? 95.285  67.527  83.896  1.00 63.02  ? 177 VAL F O   1 
ATOM 4537 C CB  . VAL D 4 177 ? 96.954  65.201  85.250  1.00 62.02  ? 177 VAL F CB  1 
ATOM 4538 C CG1 . VAL D 4 177 ? 97.225  64.198  84.136  1.00 60.60  ? 177 VAL F CG1 1 
ATOM 4539 C CG2 . VAL D 4 177 ? 97.716  64.825  86.510  1.00 62.43  ? 177 VAL F CG2 1 
ATOM 4540 N N   . MET D 4 178 ? 96.914  66.969  82.435  1.00 58.93  ? 178 MET F N   1 
ATOM 4541 C CA  . MET D 4 178 ? 96.136  67.269  81.243  1.00 60.07  ? 178 MET F CA  1 
ATOM 4542 C C   . MET D 4 178 ? 96.192  66.088  80.289  1.00 62.93  ? 178 MET F C   1 
ATOM 4543 O O   . MET D 4 178 ? 97.116  65.272  80.327  1.00 60.98  ? 178 MET F O   1 
ATOM 4544 C CB  . MET D 4 178 ? 96.646  68.517  80.532  1.00 59.55  ? 178 MET F CB  1 
ATOM 4545 C CG  . MET D 4 178 ? 96.882  69.679  81.448  1.00 60.38  ? 178 MET F CG  1 
ATOM 4546 S SD  . MET D 4 178 ? 97.020  71.206  80.526  1.00 60.71  ? 178 MET F SD  1 
ATOM 4547 C CE  . MET D 4 178 ? 98.463  71.877  81.317  1.00 54.03  ? 178 MET F CE  1 
ATOM 4548 N N   . THR D 4 179 ? 95.184  66.010  79.423  1.00 71.47  ? 179 THR F N   1 
ATOM 4549 C CA  . THR D 4 179 ? 95.054  64.917  78.473  1.00 72.79  ? 179 THR F CA  1 
ATOM 4550 C C   . THR D 4 179 ? 94.869  65.481  77.073  1.00 71.06  ? 179 THR F C   1 
ATOM 4551 O O   . THR D 4 179 ? 94.034  66.364  76.859  1.00 70.71  ? 179 THR F O   1 
ATOM 4552 C CB  . THR D 4 179 ? 93.875  64.009  78.837  1.00 74.19  ? 179 THR F CB  1 
ATOM 4553 O OG1 . THR D 4 179 ? 93.981  63.615  80.211  1.00 73.98  ? 179 THR F OG1 1 
ATOM 4554 C CG2 . THR D 4 179 ? 93.861  62.767  77.957  1.00 72.06  ? 179 THR F CG2 1 
ATOM 4555 N N   . GLN D 4 180 ? 95.654  64.969  76.131  1.00 69.38  ? 180 GLN F N   1 
ATOM 4556 C CA  . GLN D 4 180 ? 95.530  65.262  74.708  1.00 67.80  ? 180 GLN F CA  1 
ATOM 4557 C C   . GLN D 4 180 ? 95.555  63.962  73.919  1.00 70.27  ? 180 GLN F C   1 
ATOM 4558 O O   . GLN D 4 180 ? 96.292  63.804  72.944  1.00 69.73  ? 180 GLN F O   1 
ATOM 4559 C CB  . GLN D 4 180 ? 96.637  66.199  74.235  1.00 68.67  ? 180 GLN F CB  1 
ATOM 4560 C CG  . GLN D 4 180 ? 96.614  67.576  74.882  1.00 67.17  ? 180 GLN F CG  1 
ATOM 4561 C CD  . GLN D 4 180 ? 97.464  68.586  74.138  1.00 66.60  ? 180 GLN F CD  1 
ATOM 4562 O OE1 . GLN D 4 180 ? 98.354  69.208  74.714  1.00 68.45  ? 180 GLN F OE1 1 
ATOM 4563 N NE2 . GLN D 4 180 ? 97.186  68.763  72.852  1.00 67.98  ? 180 GLN F NE2 1 
ATOM 4564 N N   . ALA D 4 181 ? 94.739  62.999  74.359  1.00 83.36  ? 181 ALA F N   1 
ATOM 4565 C CA  . ALA D 4 181 ? 94.791  61.657  73.789  1.00 84.22  ? 181 ALA F CA  1 
ATOM 4566 C C   . ALA D 4 181 ? 94.603  61.673  72.278  1.00 84.83  ? 181 ALA F C   1 
ATOM 4567 O O   . ALA D 4 181 ? 95.159  60.820  71.577  1.00 83.68  ? 181 ALA F O   1 
ATOM 4568 C CB  . ALA D 4 181 ? 93.730  60.771  74.443  1.00 82.22  ? 181 ALA F CB  1 
ATOM 4569 N N   . THR D 4 182 ? 93.835  62.624  71.758  1.00 89.56  ? 182 THR F N   1 
ATOM 4570 C CA  . THR D 4 182 ? 93.674  62.757  70.314  1.00 90.33  ? 182 THR F CA  1 
ATOM 4571 C C   . THR D 4 182 ? 94.985  63.255  69.720  1.00 89.75  ? 182 THR F C   1 
ATOM 4572 O O   . THR D 4 182 ? 95.372  64.408  69.935  1.00 90.54  ? 182 THR F O   1 
ATOM 4573 C CB  . THR D 4 182 ? 92.527  63.712  69.995  1.00 90.36  ? 182 THR F CB  1 
ATOM 4574 O OG1 . THR D 4 182 ? 91.360  63.326  70.732  1.00 89.88  ? 182 THR F OG1 1 
ATOM 4575 C CG2 . THR D 4 182 ? 92.208  63.689  68.506  1.00 89.55  ? 182 THR F CG2 1 
ATOM 4576 N N   . SER D 4 183 ? 95.681  62.386  68.977  1.00 93.01  ? 183 SER F N   1 
ATOM 4577 C CA  . SER D 4 183 ? 96.979  62.749  68.418  1.00 93.27  ? 183 SER F CA  1 
ATOM 4578 C C   . SER D 4 183 ? 97.162  62.261  66.984  1.00 95.05  ? 183 SER F C   1 
ATOM 4579 O O   . SER D 4 183 ? 98.303  62.127  66.528  1.00 95.68  ? 183 SER F O   1 
ATOM 4580 C CB  . SER D 4 183 ? 98.114  62.197  69.286  1.00 93.61  ? 183 SER F CB  1 
ATOM 4581 O OG  . SER D 4 183 ? 99.373  62.626  68.798  1.00 94.00  ? 183 SER F OG  1 
ATOM 4582 N N   . SER D 4 184 ? 96.075  61.988  66.263  1.00 109.27 ? 184 SER F N   1 
ATOM 4583 C CA  . SER D 4 184 ? 96.169  61.567  64.866  1.00 110.87 ? 184 SER F CA  1 
ATOM 4584 C C   . SER D 4 184 ? 94.857  61.950  64.189  1.00 110.85 ? 184 SER F C   1 
ATOM 4585 O O   . SER D 4 184 ? 93.842  61.272  64.372  1.00 110.32 ? 184 SER F O   1 
ATOM 4586 C CB  . SER D 4 184 ? 96.440  60.074  64.755  1.00 109.09 ? 184 SER F CB  1 
ATOM 4587 O OG  . SER D 4 184 ? 96.595  59.687  63.400  1.00 109.35 ? 184 SER F OG  1 
ATOM 4588 N N   . VAL D 4 185 ? 94.885  63.033  63.419  1.00 114.90 ? 185 VAL F N   1 
ATOM 4589 C CA  . VAL D 4 185 ? 93.699  63.509  62.713  1.00 115.37 ? 185 VAL F CA  1 
ATOM 4590 C C   . VAL D 4 185 ? 94.089  63.862  61.283  1.00 115.34 ? 185 VAL F C   1 
ATOM 4591 O O   . VAL D 4 185 ? 95.008  64.669  61.081  1.00 115.24 ? 185 VAL F O   1 
ATOM 4592 C CB  . VAL D 4 185 ? 93.073  64.717  63.427  1.00 115.40 ? 185 VAL F CB  1 
ATOM 4593 C CG1 . VAL D 4 185 ? 91.876  65.241  62.644  1.00 115.04 ? 185 VAL F CG1 1 
ATOM 4594 C CG2 . VAL D 4 185 ? 92.670  64.344  64.844  1.00 114.29 ? 185 VAL F CG2 1 
ATOM 4595 N N   . PRO D 4 186 ? 93.439  63.301  60.265  1.00 118.86 ? 186 PRO F N   1 
ATOM 4596 C CA  . PRO D 4 186 ? 93.725  63.742  58.900  1.00 119.08 ? 186 PRO F CA  1 
ATOM 4597 C C   . PRO D 4 186 ? 93.283  65.177  58.693  1.00 118.61 ? 186 PRO F C   1 
ATOM 4598 O O   . PRO D 4 186 ? 92.331  65.659  59.312  1.00 117.98 ? 186 PRO F O   1 
ATOM 4599 C CB  . PRO D 4 186 ? 92.918  62.775  58.027  1.00 118.68 ? 186 PRO F CB  1 
ATOM 4600 C CG  . PRO D 4 186 ? 91.838  62.289  58.901  1.00 118.57 ? 186 PRO F CG  1 
ATOM 4601 C CD  . PRO D 4 186 ? 92.404  62.253  60.289  1.00 118.12 ? 186 PRO F CD  1 
ATOM 4602 N N   . VAL D 4 187 ? 93.997  65.860  57.808  1.00 118.92 ? 187 VAL F N   1 
ATOM 4603 C CA  . VAL D 4 187 ? 93.777  67.270  57.523  1.00 119.57 ? 187 VAL F CA  1 
ATOM 4604 C C   . VAL D 4 187 ? 93.690  67.449  56.017  1.00 119.70 ? 187 VAL F C   1 
ATOM 4605 O O   . VAL D 4 187 ? 94.321  66.701  55.262  1.00 118.49 ? 187 VAL F O   1 
ATOM 4606 C CB  . VAL D 4 187 ? 94.899  68.153  58.097  1.00 119.88 ? 187 VAL F CB  1 
ATOM 4607 C CG1 . VAL D 4 187 ? 94.791  69.564  57.523  1.00 119.21 ? 187 VAL F CG1 1 
ATOM 4608 C CG2 . VAL D 4 187 ? 94.865  68.144  59.628  1.00 118.58 ? 187 VAL F CG2 1 
ATOM 4609 N N   . THR D 4 188 ? 92.890  68.417  55.580  1.00 121.39 ? 188 THR F N   1 
ATOM 4610 C CA  . THR D 4 188 ? 92.848  68.756  54.170  1.00 121.53 ? 188 THR F CA  1 
ATOM 4611 C C   . THR D 4 188 ? 93.018  70.260  53.971  1.00 120.95 ? 188 THR F C   1 
ATOM 4612 O O   . THR D 4 188 ? 92.612  71.051  54.830  1.00 120.31 ? 188 THR F O   1 
ATOM 4613 C CB  . THR D 4 188 ? 91.529  68.292  53.544  1.00 121.11 ? 188 THR F CB  1 
ATOM 4614 O OG1 . THR D 4 188 ? 90.429  68.778  54.322  1.00 119.77 ? 188 THR F OG1 1 
ATOM 4615 C CG2 . THR D 4 188 ? 91.489  66.767  53.491  1.00 120.74 ? 188 THR F CG2 1 
ATOM 4616 N N   . PRO D 4 189 ? 93.611  70.687  52.853  1.00 120.60 ? 189 PRO F N   1 
ATOM 4617 C CA  . PRO D 4 189 ? 93.798  72.125  52.633  1.00 120.62 ? 189 PRO F CA  1 
ATOM 4618 C C   . PRO D 4 189 ? 92.464  72.855  52.599  1.00 121.04 ? 189 PRO F C   1 
ATOM 4619 O O   . PRO D 4 189 ? 91.459  72.339  52.104  1.00 120.46 ? 189 PRO F O   1 
ATOM 4620 C CB  . PRO D 4 189 ? 94.514  72.193  51.277  1.00 119.99 ? 189 PRO F CB  1 
ATOM 4621 C CG  . PRO D 4 189 ? 95.103  70.844  51.073  1.00 120.23 ? 189 PRO F CG  1 
ATOM 4622 C CD  . PRO D 4 189 ? 94.190  69.885  51.761  1.00 119.91 ? 189 PRO F CD  1 
ATOM 4623 N N   . GLY D 4 190 ? 92.464  74.070  53.137  1.00 121.65 ? 190 GLY F N   1 
ATOM 4624 C CA  . GLY D 4 190 ? 91.235  74.846  53.210  1.00 120.54 ? 190 GLY F CA  1 
ATOM 4625 C C   . GLY D 4 190 ? 90.171  74.202  54.071  1.00 120.70 ? 190 GLY F C   1 
ATOM 4626 O O   . GLY D 4 190 ? 88.995  74.177  53.687  1.00 120.71 ? 190 GLY F O   1 
ATOM 4627 N N   . GLU D 4 191 ? 90.558  73.675  55.231  1.00 113.05 ? 191 GLU F N   1 
ATOM 4628 C CA  . GLU D 4 191 ? 89.637  72.995  56.128  1.00 112.99 ? 191 GLU F CA  1 
ATOM 4629 C C   . GLU D 4 191 ? 89.905  73.467  57.551  1.00 112.68 ? 191 GLU F C   1 
ATOM 4630 O O   . GLU D 4 191 ? 91.000  73.932  57.875  1.00 112.86 ? 191 GLU F O   1 
ATOM 4631 C CB  . GLU D 4 191 ? 89.780  71.469  56.016  1.00 113.20 ? 191 GLU F CB  1 
ATOM 4632 C CG  . GLU D 4 191 ? 88.522  70.683  56.369  1.00 113.31 ? 191 GLU F CG  1 
ATOM 4633 C CD  . GLU D 4 191 ? 88.362  70.449  57.857  1.00 113.21 ? 191 GLU F CD  1 
ATOM 4634 O OE1 . GLU D 4 191 ? 89.340  70.661  58.602  1.00 113.04 ? 191 GLU F OE1 1 
ATOM 4635 O OE2 . GLU D 4 191 ? 87.257  70.053  58.284  1.00 112.82 ? 191 GLU F OE2 1 
ATOM 4636 N N   . SER D 4 192 ? 88.883  73.355  58.395  1.00 107.73 ? 192 SER F N   1 
ATOM 4637 C CA  . SER D 4 192 ? 88.933  73.829  59.772  1.00 108.17 ? 192 SER F CA  1 
ATOM 4638 C C   . SER D 4 192 ? 88.884  72.648  60.731  1.00 108.47 ? 192 SER F C   1 
ATOM 4639 O O   . SER D 4 192 ? 88.026  71.770  60.597  1.00 108.55 ? 192 SER F O   1 
ATOM 4640 C CB  . SER D 4 192 ? 87.773  74.784  60.057  1.00 107.97 ? 192 SER F CB  1 
ATOM 4641 O OG  . SER D 4 192 ? 87.761  75.177  61.418  1.00 106.85 ? 192 SER F OG  1 
ATOM 4642 N N   . VAL D 4 193 ? 89.806  72.633  61.695  1.00 100.40 ? 193 VAL F N   1 
ATOM 4643 C CA  . VAL D 4 193 ? 89.870  71.596  62.716  1.00 99.62  ? 193 VAL F CA  1 
ATOM 4644 C C   . VAL D 4 193 ? 89.982  72.268  64.078  1.00 98.18  ? 193 VAL F C   1 
ATOM 4645 O O   . VAL D 4 193 ? 90.490  73.384  64.208  1.00 97.99  ? 193 VAL F O   1 
ATOM 4646 C CB  . VAL D 4 193 ? 91.054  70.628  62.487  1.00 99.67  ? 193 VAL F CB  1 
ATOM 4647 C CG1 . VAL D 4 193 ? 91.193  69.651  63.643  1.00 99.82  ? 193 VAL F CG1 1 
ATOM 4648 C CG2 . VAL D 4 193 ? 90.878  69.880  61.176  1.00 99.18  ? 193 VAL F CG2 1 
ATOM 4649 N N   . SER D 4 194 ? 89.499  71.568  65.102  1.00 85.29  ? 194 SER F N   1 
ATOM 4650 C CA  . SER D 4 194 ? 89.494  72.064  66.471  1.00 85.27  ? 194 SER F CA  1 
ATOM 4651 C C   . SER D 4 194 ? 90.288  71.117  67.358  1.00 85.27  ? 194 SER F C   1 
ATOM 4652 O O   . SER D 4 194 ? 90.028  69.909  67.374  1.00 85.69  ? 194 SER F O   1 
ATOM 4653 C CB  . SER D 4 194 ? 88.065  72.203  66.998  1.00 86.51  ? 194 SER F CB  1 
ATOM 4654 O OG  . SER D 4 194 ? 88.060  72.612  68.354  1.00 86.79  ? 194 SER F OG  1 
ATOM 4655 N N   . ILE D 4 195 ? 91.252  71.667  68.090  1.00 76.10  ? 195 ILE F N   1 
ATOM 4656 C CA  . ILE D 4 195 ? 92.037  70.900  69.044  1.00 74.46  ? 195 ILE F CA  1 
ATOM 4657 C C   . ILE D 4 195 ? 91.391  71.030  70.418  1.00 74.15  ? 195 ILE F C   1 
ATOM 4658 O O   . ILE D 4 195 ? 90.642  71.970  70.691  1.00 74.89  ? 195 ILE F O   1 
ATOM 4659 C CB  . ILE D 4 195 ? 93.510  71.368  69.053  1.00 74.51  ? 195 ILE F CB  1 
ATOM 4660 C CG1 . ILE D 4 195 ? 94.145  71.102  67.685  1.00 74.55  ? 195 ILE F CG1 1 
ATOM 4661 C CG2 . ILE D 4 195 ? 94.305  70.672  70.157  1.00 74.40  ? 195 ILE F CG2 1 
ATOM 4662 C CD1 . ILE D 4 195 ? 95.515  71.714  67.500  1.00 76.07  ? 195 ILE F CD1 1 
ATOM 4663 N N   . SER D 4 196 ? 91.672  70.064  71.291  1.00 70.50  ? 196 SER F N   1 
ATOM 4664 C CA  . SER D 4 196 ? 91.082  70.011  72.620  1.00 71.10  ? 196 SER F CA  1 
ATOM 4665 C C   . SER D 4 196 ? 92.178  69.886  73.670  1.00 68.40  ? 196 SER F C   1 
ATOM 4666 O O   . SER D 4 196 ? 93.287  69.424  73.393  1.00 66.80  ? 196 SER F O   1 
ATOM 4667 C CB  . SER D 4 196 ? 90.100  68.840  72.749  1.00 71.84  ? 196 SER F CB  1 
ATOM 4668 O OG  . SER D 4 196 ? 89.007  68.988  71.861  1.00 70.10  ? 196 SER F OG  1 
ATOM 4669 N N   . CYS D 4 197 ? 91.846  70.319  74.885  1.00 69.47  ? 197 CYS F N   1 
ATOM 4670 C CA  . CYS D 4 197 ? 92.762  70.260  76.017  1.00 67.29  ? 197 CYS F CA  1 
ATOM 4671 C C   . CYS D 4 197 ? 91.942  70.425  77.287  1.00 68.76  ? 197 CYS F C   1 
ATOM 4672 O O   . CYS D 4 197 ? 91.135  71.354  77.382  1.00 70.59  ? 197 CYS F O   1 
ATOM 4673 C CB  . CYS D 4 197 ? 93.833  71.352  75.923  1.00 67.60  ? 197 CYS F CB  1 
ATOM 4674 S SG  . CYS D 4 197 ? 94.988  71.413  77.317  1.00 71.20  ? 197 CYS F SG  1 
ATOM 4675 N N   . ARG D 4 198 ? 92.141  69.527  78.249  1.00 76.22  ? 198 ARG F N   1 
ATOM 4676 C CA  . ARG D 4 198 ? 91.372  69.518  79.485  1.00 76.04  ? 198 ARG F CA  1 
ATOM 4677 C C   . ARG D 4 198 ? 92.310  69.451  80.679  1.00 75.35  ? 198 ARG F C   1 
ATOM 4678 O O   . ARG D 4 198 ? 93.284  68.693  80.671  1.00 76.27  ? 198 ARG F O   1 
ATOM 4679 C CB  . ARG D 4 198 ? 90.402  68.337  79.515  1.00 75.56  ? 198 ARG F CB  1 
ATOM 4680 C CG  . ARG D 4 198 ? 89.259  68.459  78.523  1.00 76.36  ? 198 ARG F CG  1 
ATOM 4681 C CD  . ARG D 4 198 ? 88.657  67.107  78.170  1.00 75.89  ? 198 ARG F CD  1 
ATOM 4682 N NE  . ARG D 4 198 ? 89.536  66.320  77.311  1.00 78.07  ? 198 ARG F NE  1 
ATOM 4683 C CZ  . ARG D 4 198 ? 90.351  65.358  77.727  1.00 78.70  ? 198 ARG F CZ  1 
ATOM 4684 N NH1 . ARG D 4 198 ? 90.432  65.017  79.004  1.00 75.43  ? 198 ARG F NH1 1 
ATOM 4685 N NH2 . ARG D 4 198 ? 91.104  64.719  76.837  1.00 76.60  ? 198 ARG F NH2 1 
ATOM 4686 N N   . SER D 4 199 ? 92.008  70.241  81.703  1.00 66.61  ? 199 SER F N   1 
ATOM 4687 C CA  . SER D 4 199 ? 92.810  70.302  82.916  1.00 65.75  ? 199 SER F CA  1 
ATOM 4688 C C   . SER D 4 199 ? 92.106  69.580  84.059  1.00 66.91  ? 199 SER F C   1 
ATOM 4689 O O   . SER D 4 199 ? 90.884  69.417  84.068  1.00 67.25  ? 199 SER F O   1 
ATOM 4690 C CB  . SER D 4 199 ? 93.086  71.756  83.308  1.00 64.22  ? 199 SER F CB  1 
ATOM 4691 O OG  . SER D 4 199 ? 93.882  71.825  84.476  1.00 63.62  ? 199 SER F OG  1 
ATOM 4692 N N   . SER D 4 200 ? 92.905  69.141  85.035  1.00 65.60  ? 200 SER F N   1 
ATOM 4693 C CA  . SER D 4 200 ? 92.342  68.450  86.191  1.00 64.32  ? 200 SER F CA  1 
ATOM 4694 C C   . SER D 4 200 ? 91.547  69.403  87.075  1.00 64.85  ? 200 SER F C   1 
ATOM 4695 O O   . SER D 4 200 ? 90.447  69.064  87.527  1.00 65.14  ? 200 SER F O   1 
ATOM 4696 C CB  . SER D 4 200 ? 93.457  67.778  86.991  1.00 64.31  ? 200 SER F CB  1 
ATOM 4697 O OG  . SER D 4 200 ? 94.385  68.730  87.476  1.00 63.53  ? 200 SER F OG  1 
ATOM 4698 N N   . LYS D 4 201 ? 92.081  70.593  87.333  1.00 62.86  ? 201 LYS F N   1 
ATOM 4699 C CA  . LYS D 4 201 ? 91.414  71.613  88.132  1.00 59.73  ? 201 LYS F CA  1 
ATOM 4700 C C   . LYS D 4 201 ? 91.167  72.853  87.275  1.00 59.67  ? 201 LYS F C   1 
ATOM 4701 O O   . LYS D 4 201 ? 91.566  72.921  86.110  1.00 58.07  ? 201 LYS F O   1 
ATOM 4702 C CB  . LYS D 4 201 ? 92.236  71.955  89.378  1.00 58.31  ? 201 LYS F CB  1 
ATOM 4703 C CG  . LYS D 4 201 ? 93.537  72.693  89.106  1.00 57.77  ? 201 LYS F CG  1 
ATOM 4704 C CD  . LYS D 4 201 ? 94.261  73.037  90.400  1.00 57.08  ? 201 LYS F CD  1 
ATOM 4705 C CE  . LYS D 4 201 ? 93.515  74.095  91.196  1.00 56.00  ? 201 LYS F CE  1 
ATOM 4706 N NZ  . LYS D 4 201 ? 94.307  74.588  92.353  1.00 57.55  ? 201 LYS F NZ  1 
ATOM 4707 N N   . SER D 4 202 ? 90.506  73.843  87.868  1.00 57.28  ? 202 SER F N   1 
ATOM 4708 C CA  . SER D 4 202 ? 90.132  75.054  87.148  1.00 54.86  ? 202 SER F CA  1 
ATOM 4709 C C   . SER D 4 202 ? 91.331  75.989  87.050  1.00 52.34  ? 202 SER F C   1 
ATOM 4710 O O   . SER D 4 202 ? 91.913  76.372  88.071  1.00 52.12  ? 202 SER F O   1 
ATOM 4711 C CB  . SER D 4 202 ? 88.969  75.750  87.849  1.00 52.13  ? 202 SER F CB  1 
ATOM 4712 O OG  . SER D 4 202 ? 88.582  76.921  87.153  1.00 55.65  ? 202 SER F OG  1 
ATOM 4713 N N   . LEU D 4 203 ? 91.697  76.357  85.821  1.00 44.04  ? 203 LEU F N   1 
ATOM 4714 C CA  . LEU D 4 203 ? 92.808  77.272  85.593  1.00 45.79  ? 203 LEU F CA  1 
ATOM 4715 C C   . LEU D 4 203 ? 92.410  78.737  85.714  1.00 43.35  ? 203 LEU F C   1 
ATOM 4716 O O   . LEU D 4 203 ? 93.294  79.595  85.805  1.00 41.96  ? 203 LEU F O   1 
ATOM 4717 C CB  . LEU D 4 203 ? 93.415  77.019  84.210  1.00 47.83  ? 203 LEU F CB  1 
ATOM 4718 C CG  . LEU D 4 203 ? 94.176  75.701  84.036  1.00 41.39  ? 203 LEU F CG  1 
ATOM 4719 C CD1 . LEU D 4 203 ? 94.546  75.487  82.582  1.00 35.50  ? 203 LEU F CD1 1 
ATOM 4720 C CD2 . LEU D 4 203 ? 95.418  75.670  84.911  1.00 40.86  ? 203 LEU F CD2 1 
ATOM 4721 N N   . LEU D 4 204 ? 91.115  79.044  85.726  1.00 44.03  ? 204 LEU F N   1 
ATOM 4722 C CA  . LEU D 4 204 ? 90.672  80.417  85.920  1.00 43.27  ? 204 LEU F CA  1 
ATOM 4723 C C   . LEU D 4 204 ? 91.028  80.888  87.324  1.00 41.93  ? 204 LEU F C   1 
ATOM 4724 O O   . LEU D 4 204 ? 90.912  80.137  88.295  1.00 42.23  ? 204 LEU F O   1 
ATOM 4725 C CB  . LEU D 4 204 ? 89.164  80.522  85.693  1.00 40.20  ? 204 LEU F CB  1 
ATOM 4726 C CG  . LEU D 4 204 ? 88.490  81.860  86.010  1.00 40.04  ? 204 LEU F CG  1 
ATOM 4727 C CD1 . LEU D 4 204 ? 88.980  82.960  85.087  1.00 41.11  ? 204 LEU F CD1 1 
ATOM 4728 C CD2 . LEU D 4 204 ? 86.982  81.721  85.921  1.00 41.30  ? 204 LEU F CD2 1 
ATOM 4729 N N   . HIS D 4 205 ? 91.464  82.138  87.426  1.00 39.27  ? 205 HIS F N   1 
ATOM 4730 C CA  . HIS D 4 205 ? 91.856  82.735  88.692  1.00 35.52  ? 205 HIS F CA  1 
ATOM 4731 C C   . HIS D 4 205 ? 90.844  83.796  89.108  1.00 32.85  ? 205 HIS F C   1 
ATOM 4732 O O   . HIS D 4 205 ? 89.959  84.187  88.343  1.00 30.19  ? 205 HIS F O   1 
ATOM 4733 C CB  . HIS D 4 205 ? 93.260  83.339  88.592  1.00 30.39  ? 205 HIS F CB  1 
ATOM 4734 C CG  . HIS D 4 205 ? 93.923  83.543  89.918  1.00 32.70  ? 205 HIS F CG  1 
ATOM 4735 N ND1 . HIS D 4 205 ? 93.977  84.769  90.542  1.00 36.06  ? 205 HIS F ND1 1 
ATOM 4736 C CD2 . HIS D 4 205 ? 94.550  82.674  90.743  1.00 31.23  ? 205 HIS F CD2 1 
ATOM 4737 C CE1 . HIS D 4 205 ? 94.616  84.649  91.691  1.00 33.92  ? 205 HIS F CE1 1 
ATOM 4738 N NE2 . HIS D 4 205 ? 94.974  83.387  91.837  1.00 30.82  ? 205 HIS F NE2 1 
ATOM 4739 N N   . SER D 4 206 ? 90.989  84.261  90.351  1.00 37.11  ? 206 SER F N   1 
ATOM 4740 C CA  . SER D 4 206 ? 90.060  85.246  90.894  1.00 39.23  ? 206 SER F CA  1 
ATOM 4741 C C   . SER D 4 206 ? 90.175  86.588  90.183  1.00 40.05  ? 206 SER F C   1 
ATOM 4742 O O   . SER D 4 206 ? 89.196  87.340  90.129  1.00 40.77  ? 206 SER F O   1 
ATOM 4743 C CB  . SER D 4 206 ? 90.307  85.422  92.391  1.00 36.12  ? 206 SER F CB  1 
ATOM 4744 O OG  . SER D 4 206 ? 90.131  84.199  93.082  1.00 38.94  ? 206 SER F OG  1 
ATOM 4745 N N   . ASN D 4 207 ? 91.346  86.905  89.633  1.00 34.95  ? 207 ASN F N   1 
ATOM 4746 C CA  . ASN D 4 207 ? 91.546  88.175  88.948  1.00 28.34  ? 207 ASN F CA  1 
ATOM 4747 C C   . ASN D 4 207 ? 91.059  88.155  87.505  1.00 29.03  ? 207 ASN F C   1 
ATOM 4748 O O   . ASN D 4 207 ? 91.204  89.163  86.808  1.00 37.94  ? 207 ASN F O   1 
ATOM 4749 C CB  . ASN D 4 207 ? 93.024  88.577  88.997  1.00 31.79  ? 207 ASN F CB  1 
ATOM 4750 C CG  . ASN D 4 207 ? 93.948  87.514  88.438  1.00 31.20  ? 207 ASN F CG  1 
ATOM 4751 O OD1 . ASN D 4 207 ? 93.615  86.822  87.478  1.00 35.58  ? 207 ASN F OD1 1 
ATOM 4752 N ND2 . ASN D 4 207 ? 95.122  87.386  89.039  1.00 29.97  ? 207 ASN F ND2 1 
ATOM 4753 N N   . GLY D 4 208 ? 90.491  87.044  87.041  1.00 31.12  ? 208 GLY F N   1 
ATOM 4754 C CA  . GLY D 4 208 ? 89.872  86.976  85.735  1.00 35.00  ? 208 GLY F CA  1 
ATOM 4755 C C   . GLY D 4 208 ? 90.723  86.375  84.640  1.00 38.11  ? 208 GLY F C   1 
ATOM 4756 O O   . GLY D 4 208 ? 90.232  86.226  83.516  1.00 39.93  ? 208 GLY F O   1 
ATOM 4757 N N   . ASN D 4 209 ? 91.970  86.017  84.929  1.00 42.61  ? 209 ASN F N   1 
ATOM 4758 C CA  . ASN D 4 209 ? 92.884  85.470  83.936  1.00 37.40  ? 209 ASN F CA  1 
ATOM 4759 C C   . ASN D 4 209 ? 92.872  83.951  84.010  1.00 33.00  ? 209 ASN F C   1 
ATOM 4760 O O   . ASN D 4 209 ? 92.970  83.378  85.098  1.00 38.42  ? 209 ASN F O   1 
ATOM 4761 C CB  . ASN D 4 209 ? 94.303  85.990  84.163  1.00 36.59  ? 209 ASN F CB  1 
ATOM 4762 C CG  . ASN D 4 209 ? 94.424  87.477  83.924  1.00 37.96  ? 209 ASN F CG  1 
ATOM 4763 O OD1 . ASN D 4 209 ? 93.849  88.013  82.979  1.00 38.16  ? 209 ASN F OD1 1 
ATOM 4764 N ND2 . ASN D 4 209 ? 95.177  88.153  84.779  1.00 36.10  ? 209 ASN F ND2 1 
ATOM 4765 N N   . THR D 4 210 ? 92.747  83.306  82.855  1.00 30.49  ? 210 THR F N   1 
ATOM 4766 C CA  . THR D 4 210 ? 92.864  81.859  82.736  1.00 30.43  ? 210 THR F CA  1 
ATOM 4767 C C   . THR D 4 210 ? 94.137  81.552  81.963  1.00 36.84  ? 210 THR F C   1 
ATOM 4768 O O   . THR D 4 210 ? 94.295  81.997  80.823  1.00 46.97  ? 210 THR F O   1 
ATOM 4769 C CB  . THR D 4 210 ? 91.653  81.261  82.025  1.00 41.80  ? 210 THR F CB  1 
ATOM 4770 O OG1 . THR D 4 210 ? 90.451  81.796  82.589  1.00 47.38  ? 210 THR F OG1 1 
ATOM 4771 C CG2 . THR D 4 210 ? 91.647  79.745  82.161  1.00 38.54  ? 210 THR F CG2 1 
ATOM 4772 N N   . TYR D 4 211 ? 95.031  80.785  82.576  1.00 38.79  ? 211 TYR F N   1 
ATOM 4773 C CA  . TYR D 4 211 ? 96.380  80.582  82.057  1.00 31.52  ? 211 TYR F CA  1 
ATOM 4774 C C   . TYR D 4 211 ? 96.435  79.256  81.307  1.00 32.78  ? 211 TYR F C   1 
ATOM 4775 O O   . TYR D 4 211 ? 96.676  78.199  81.890  1.00 28.87  ? 211 TYR F O   1 
ATOM 4776 C CB  . TYR D 4 211 ? 97.388  80.622  83.194  1.00 24.31  ? 211 TYR F CB  1 
ATOM 4777 C CG  . TYR D 4 211 ? 97.194  81.784  84.134  1.00 18.45  ? 211 TYR F CG  1 
ATOM 4778 C CD1 . TYR D 4 211 ? 97.755  83.018  83.864  1.00 24.49  ? 211 TYR F CD1 1 
ATOM 4779 C CD2 . TYR D 4 211 ? 96.455  81.642  85.296  1.00 21.87  ? 211 TYR F CD2 1 
ATOM 4780 C CE1 . TYR D 4 211 ? 97.586  84.081  84.722  1.00 26.93  ? 211 TYR F CE1 1 
ATOM 4781 C CE2 . TYR D 4 211 ? 96.281  82.699  86.161  1.00 25.94  ? 211 TYR F CE2 1 
ATOM 4782 C CZ  . TYR D 4 211 ? 96.849  83.916  85.868  1.00 28.92  ? 211 TYR F CZ  1 
ATOM 4783 O OH  . TYR D 4 211 ? 96.680  84.975  86.726  1.00 31.35  ? 211 TYR F OH  1 
ATOM 4784 N N   . LEU D 4 212 ? 96.199  79.318  79.999  1.00 31.08  ? 212 LEU F N   1 
ATOM 4785 C CA  . LEU D 4 212 ? 96.421  78.191  79.103  1.00 32.47  ? 212 LEU F CA  1 
ATOM 4786 C C   . LEU D 4 212 ? 97.173  78.694  77.881  1.00 39.24  ? 212 LEU F C   1 
ATOM 4787 O O   . LEU D 4 212 ? 96.749  79.666  77.247  1.00 35.32  ? 212 LEU F O   1 
ATOM 4788 C CB  . LEU D 4 212 ? 95.107  77.526  78.692  1.00 39.55  ? 212 LEU F CB  1 
ATOM 4789 C CG  . LEU D 4 212 ? 95.292  76.256  77.857  1.00 39.40  ? 212 LEU F CG  1 
ATOM 4790 C CD1 . LEU D 4 212 ? 94.289  75.205  78.249  1.00 36.64  ? 212 LEU F CD1 1 
ATOM 4791 C CD2 . LEU D 4 212 ? 95.169  76.556  76.374  1.00 32.66  ? 212 LEU F CD2 1 
ATOM 4792 N N   . TYR D 4 213 ? 98.278  78.031  77.554  1.00 49.04  ? 213 TYR F N   1 
ATOM 4793 C CA  . TYR D 4 213 ? 99.149  78.412  76.455  1.00 39.96  ? 213 TYR F CA  1 
ATOM 4794 C C   . TYR D 4 213 ? 99.170  77.310  75.404  1.00 37.85  ? 213 TYR F C   1 
ATOM 4795 O O   . TYR D 4 213 ? 99.064  76.124  75.724  1.00 45.07  ? 213 TYR F O   1 
ATOM 4796 C CB  . TYR D 4 213 ? 100.570 78.683  76.955  1.00 38.58  ? 213 TYR F CB  1 
ATOM 4797 C CG  . TYR D 4 213 ? 100.668 79.838  77.921  1.00 36.39  ? 213 TYR F CG  1 
ATOM 4798 C CD1 . TYR D 4 213 ? 100.155 79.742  79.205  1.00 36.91  ? 213 TYR F CD1 1 
ATOM 4799 C CD2 . TYR D 4 213 ? 101.280 81.024  77.550  1.00 35.21  ? 213 TYR F CD2 1 
ATOM 4800 C CE1 . TYR D 4 213 ? 100.243 80.799  80.090  1.00 37.27  ? 213 TYR F CE1 1 
ATOM 4801 C CE2 . TYR D 4 213 ? 101.374 82.084  78.427  1.00 33.79  ? 213 TYR F CE2 1 
ATOM 4802 C CZ  . TYR D 4 213 ? 100.855 81.967  79.695  1.00 33.56  ? 213 TYR F CZ  1 
ATOM 4803 O OH  . TYR D 4 213 ? 100.948 83.023  80.569  1.00 29.37  ? 213 TYR F OH  1 
ATOM 4804 N N   . TRP D 4 214 ? 99.305  77.715  74.144  1.00 46.27  ? 214 TRP F N   1 
ATOM 4805 C CA  . TRP D 4 214 ? 99.354  76.799  73.014  1.00 49.77  ? 214 TRP F CA  1 
ATOM 4806 C C   . TRP D 4 214 ? 100.699 76.928  72.314  1.00 46.10  ? 214 TRP F C   1 
ATOM 4807 O O   . TRP D 4 214 ? 101.256 78.025  72.220  1.00 46.64  ? 214 TRP F O   1 
ATOM 4808 C CB  . TRP D 4 214 ? 98.219  77.076  72.024  1.00 47.58  ? 214 TRP F CB  1 
ATOM 4809 C CG  . TRP D 4 214 ? 96.879  76.618  72.509  1.00 49.53  ? 214 TRP F CG  1 
ATOM 4810 C CD1 . TRP D 4 214 ? 95.900  77.388  73.056  1.00 49.09  ? 214 TRP F CD1 1 
ATOM 4811 C CD2 . TRP D 4 214 ? 96.372  75.277  72.493  1.00 52.04  ? 214 TRP F CD2 1 
ATOM 4812 N NE1 . TRP D 4 214 ? 94.814  76.613  73.380  1.00 49.60  ? 214 TRP F NE1 1 
ATOM 4813 C CE2 . TRP D 4 214 ? 95.080  75.313  73.045  1.00 52.22  ? 214 TRP F CE2 1 
ATOM 4814 C CE3 . TRP D 4 214 ? 96.887  74.050  72.064  1.00 49.77  ? 214 TRP F CE3 1 
ATOM 4815 C CZ2 . TRP D 4 214 ? 94.294  74.171  73.180  1.00 51.18  ? 214 TRP F CZ2 1 
ATOM 4816 C CZ3 . TRP D 4 214 ? 96.106  72.921  72.199  1.00 50.28  ? 214 TRP F CZ3 1 
ATOM 4817 C CH2 . TRP D 4 214 ? 94.825  72.988  72.753  1.00 52.83  ? 214 TRP F CH2 1 
ATOM 4818 N N   . PHE D 4 215 ? 101.223 75.800  71.837  1.00 41.27  ? 215 PHE F N   1 
ATOM 4819 C CA  . PHE D 4 215 ? 102.494 75.770  71.130  1.00 44.90  ? 215 PHE F CA  1 
ATOM 4820 C C   . PHE D 4 215 ? 102.368 74.866  69.914  1.00 44.31  ? 215 PHE F C   1 
ATOM 4821 O O   . PHE D 4 215 ? 101.559 73.937  69.895  1.00 46.59  ? 215 PHE F O   1 
ATOM 4822 C CB  . PHE D 4 215 ? 103.639 75.276  72.029  1.00 45.50  ? 215 PHE F CB  1 
ATOM 4823 C CG  . PHE D 4 215 ? 103.873 76.131  73.238  1.00 41.44  ? 215 PHE F CG  1 
ATOM 4824 C CD1 . PHE D 4 215 ? 104.725 77.217  73.178  1.00 37.01  ? 215 PHE F CD1 1 
ATOM 4825 C CD2 . PHE D 4 215 ? 103.243 75.848  74.436  1.00 44.30  ? 215 PHE F CD2 1 
ATOM 4826 C CE1 . PHE D 4 215 ? 104.940 78.006  74.289  1.00 41.78  ? 215 PHE F CE1 1 
ATOM 4827 C CE2 . PHE D 4 215 ? 103.456 76.635  75.548  1.00 41.31  ? 215 PHE F CE2 1 
ATOM 4828 C CZ  . PHE D 4 215 ? 104.306 77.713  75.473  1.00 38.96  ? 215 PHE F CZ  1 
ATOM 4829 N N   . LEU D 4 216 ? 103.177 75.153  68.897  1.00 49.54  ? 216 LEU F N   1 
ATOM 4830 C CA  . LEU D 4 216 ? 103.229 74.363  67.674  1.00 54.25  ? 216 LEU F CA  1 
ATOM 4831 C C   . LEU D 4 216 ? 104.682 74.052  67.356  1.00 55.53  ? 216 LEU F C   1 
ATOM 4832 O O   . LEU D 4 216 ? 105.507 74.966  67.272  1.00 53.86  ? 216 LEU F O   1 
ATOM 4833 C CB  . LEU D 4 216 ? 102.580 75.111  66.504  1.00 56.47  ? 216 LEU F CB  1 
ATOM 4834 C CG  . LEU D 4 216 ? 102.932 74.659  65.084  1.00 56.57  ? 216 LEU F CG  1 
ATOM 4835 C CD1 . LEU D 4 216 ? 102.438 73.247  64.818  1.00 56.57  ? 216 LEU F CD1 1 
ATOM 4836 C CD2 . LEU D 4 216 ? 102.360 75.634  64.074  1.00 54.96  ? 216 LEU F CD2 1 
ATOM 4837 N N   . GLN D 4 217 ? 104.985 72.773  67.155  1.00 63.30  ? 217 GLN F N   1 
ATOM 4838 C CA  . GLN D 4 217 ? 106.336 72.316  66.837  1.00 65.82  ? 217 GLN F CA  1 
ATOM 4839 C C   . GLN D 4 217 ? 106.327 71.736  65.427  1.00 67.34  ? 217 GLN F C   1 
ATOM 4840 O O   . GLN D 4 217 ? 105.885 70.604  65.215  1.00 67.21  ? 217 GLN F O   1 
ATOM 4841 C CB  . GLN D 4 217 ? 106.818 71.288  67.854  1.00 63.09  ? 217 GLN F CB  1 
ATOM 4842 C CG  . GLN D 4 217 ? 108.292 70.952  67.728  1.00 61.72  ? 217 GLN F CG  1 
ATOM 4843 C CD  . GLN D 4 217 ? 108.807 70.139  68.892  1.00 63.99  ? 217 GLN F CD  1 
ATOM 4844 O OE1 . GLN D 4 217 ? 108.091 69.312  69.453  1.00 65.49  ? 217 GLN F OE1 1 
ATOM 4845 N NE2 . GLN D 4 217 ? 110.058 70.373  69.268  1.00 63.56  ? 217 GLN F NE2 1 
ATOM 4846 N N   . ARG D 4 218 ? 106.817 72.513  64.467  1.00 73.15  ? 218 ARG F N   1 
ATOM 4847 C CA  . ARG D 4 218 ? 106.950 72.010  63.113  1.00 73.00  ? 218 ARG F CA  1 
ATOM 4848 C C   . ARG D 4 218 ? 108.077 70.980  63.053  1.00 75.22  ? 218 ARG F C   1 
ATOM 4849 O O   . ARG D 4 218 ? 109.010 71.025  63.859  1.00 75.87  ? 218 ARG F O   1 
ATOM 4850 C CB  . ARG D 4 218 ? 107.228 73.152  62.140  1.00 73.42  ? 218 ARG F CB  1 
ATOM 4851 C CG  . ARG D 4 218 ? 105.978 73.882  61.673  1.00 73.74  ? 218 ARG F CG  1 
ATOM 4852 C CD  . ARG D 4 218 ? 106.319 75.039  60.748  1.00 75.21  ? 218 ARG F CD  1 
ATOM 4853 N NE  . ARG D 4 218 ? 106.720 76.233  61.483  1.00 76.93  ? 218 ARG F NE  1 
ATOM 4854 C CZ  . ARG D 4 218 ? 105.891 77.186  61.890  1.00 76.12  ? 218 ARG F CZ  1 
ATOM 4855 N NH1 . ARG D 4 218 ? 104.590 77.120  61.657  1.00 76.63  ? 218 ARG F NH1 1 
ATOM 4856 N NH2 . ARG D 4 218 ? 106.380 78.233  62.549  1.00 73.12  ? 218 ARG F NH2 1 
ATOM 4857 N N   . PRO D 4 219 ? 108.015 70.037  62.111  1.00 81.91  ? 219 PRO F N   1 
ATOM 4858 C CA  . PRO D 4 219 ? 109.024 68.970  62.075  1.00 81.61  ? 219 PRO F CA  1 
ATOM 4859 C C   . PRO D 4 219 ? 110.432 69.530  61.934  1.00 81.03  ? 219 PRO F C   1 
ATOM 4860 O O   . PRO D 4 219 ? 110.711 70.344  61.051  1.00 79.09  ? 219 PRO F O   1 
ATOM 4861 C CB  . PRO D 4 219 ? 108.620 68.141  60.851  1.00 80.99  ? 219 PRO F CB  1 
ATOM 4862 C CG  . PRO D 4 219 ? 107.190 68.451  60.630  1.00 80.39  ? 219 PRO F CG  1 
ATOM 4863 C CD  . PRO D 4 219 ? 107.008 69.871  61.049  1.00 79.94  ? 219 PRO F CD  1 
ATOM 4864 N N   . GLY D 4 220 ? 111.323 69.077  62.812  1.00 77.43  ? 220 GLY F N   1 
ATOM 4865 C CA  . GLY D 4 220 ? 112.713 69.477  62.757  1.00 76.10  ? 220 GLY F CA  1 
ATOM 4866 C C   . GLY D 4 220 ? 113.009 70.860  63.288  1.00 79.12  ? 220 GLY F C   1 
ATOM 4867 O O   . GLY D 4 220 ? 114.115 71.365  63.063  1.00 77.58  ? 220 GLY F O   1 
ATOM 4868 N N   . GLN D 4 221 ? 112.064 71.491  63.981  1.00 76.21  ? 221 GLN F N   1 
ATOM 4869 C CA  . GLN D 4 221 ? 112.234 72.840  64.503  1.00 72.01  ? 221 GLN F CA  1 
ATOM 4870 C C   . GLN D 4 221 ? 111.756 72.887  65.948  1.00 68.64  ? 221 GLN F C   1 
ATOM 4871 O O   . GLN D 4 221 ? 111.212 71.915  66.482  1.00 67.06  ? 221 GLN F O   1 
ATOM 4872 C CB  . GLN D 4 221 ? 111.476 73.860  63.646  1.00 70.38  ? 221 GLN F CB  1 
ATOM 4873 C CG  . GLN D 4 221 ? 111.936 73.917  62.201  1.00 70.02  ? 221 GLN F CG  1 
ATOM 4874 C CD  . GLN D 4 221 ? 111.106 74.868  61.365  1.00 72.62  ? 221 GLN F CD  1 
ATOM 4875 O OE1 . GLN D 4 221 ? 110.059 75.345  61.801  1.00 74.22  ? 221 GLN F OE1 1 
ATOM 4876 N NE2 . GLN D 4 221 ? 111.572 75.151  60.155  1.00 71.38  ? 221 GLN F NE2 1 
ATOM 4877 N N   . SER D 4 222 ? 111.966 74.034  66.584  1.00 59.55  ? 222 SER F N   1 
ATOM 4878 C CA  . SER D 4 222 ? 111.529 74.264  67.950  1.00 57.53  ? 222 SER F CA  1 
ATOM 4879 C C   . SER D 4 222 ? 110.095 74.776  67.973  1.00 59.89  ? 222 SER F C   1 
ATOM 4880 O O   . SER D 4 222 ? 109.604 75.323  66.982  1.00 62.79  ? 222 SER F O   1 
ATOM 4881 C CB  . SER D 4 222 ? 112.456 75.267  68.631  1.00 56.81  ? 222 SER F CB  1 
ATOM 4882 O OG  . SER D 4 222 ? 112.623 76.425  67.836  1.00 57.98  ? 222 SER F OG  1 
ATOM 4883 N N   . PRO D 4 223 ? 109.385 74.606  69.088  1.00 48.37  ? 223 PRO F N   1 
ATOM 4884 C CA  . PRO D 4 223 ? 108.005 75.100  69.164  1.00 46.92  ? 223 PRO F CA  1 
ATOM 4885 C C   . PRO D 4 223 ? 107.930 76.621  69.136  1.00 48.44  ? 223 PRO F C   1 
ATOM 4886 O O   . PRO D 4 223 ? 108.882 77.329  69.471  1.00 44.89  ? 223 PRO F O   1 
ATOM 4887 C CB  . PRO D 4 223 ? 107.497 74.550  70.502  1.00 46.64  ? 223 PRO F CB  1 
ATOM 4888 C CG  . PRO D 4 223 ? 108.418 73.448  70.852  1.00 45.72  ? 223 PRO F CG  1 
ATOM 4889 C CD  . PRO D 4 223 ? 109.741 73.803  70.270  1.00 45.50  ? 223 PRO F CD  1 
ATOM 4890 N N   . GLN D 4 224 ? 106.765 77.120  68.719  1.00 46.17  ? 224 GLN F N   1 
ATOM 4891 C CA  . GLN D 4 224 ? 106.465 78.545  68.733  1.00 45.90  ? 224 GLN F CA  1 
ATOM 4892 C C   . GLN D 4 224 ? 105.147 78.783  69.455  1.00 44.47  ? 224 GLN F C   1 
ATOM 4893 O O   . GLN D 4 224 ? 104.255 77.932  69.447  1.00 43.74  ? 224 GLN F O   1 
ATOM 4894 C CB  . GLN D 4 224 ? 106.388 79.136  67.311  1.00 43.32  ? 224 GLN F CB  1 
ATOM 4895 C CG  . GLN D 4 224 ? 105.201 78.668  66.469  1.00 46.15  ? 224 GLN F CG  1 
ATOM 4896 C CD  . GLN D 4 224 ? 104.748 79.715  65.471  1.00 48.46  ? 224 GLN F CD  1 
ATOM 4897 O OE1 . GLN D 4 224 ? 105.455 80.683  65.203  1.00 49.96  ? 224 GLN F OE1 1 
ATOM 4898 N NE2 . GLN D 4 224 ? 103.555 79.527  64.921  1.00 46.37  ? 224 GLN F NE2 1 
ATOM 4899 N N   . LEU D 4 225 ? 105.028 79.957  70.070  1.00 36.90  ? 225 LEU F N   1 
ATOM 4900 C CA  . LEU D 4 225 ? 103.812 80.326  70.781  1.00 36.90  ? 225 LEU F CA  1 
ATOM 4901 C C   . LEU D 4 225 ? 102.724 80.719  69.790  1.00 43.90  ? 225 LEU F C   1 
ATOM 4902 O O   . LEU D 4 225 ? 102.977 81.467  68.842  1.00 48.48  ? 225 LEU F O   1 
ATOM 4903 C CB  . LEU D 4 225 ? 104.092 81.480  71.742  1.00 34.80  ? 225 LEU F CB  1 
ATOM 4904 C CG  . LEU D 4 225 ? 102.903 82.068  72.506  1.00 33.43  ? 225 LEU F CG  1 
ATOM 4905 C CD1 . LEU D 4 225 ? 102.314 81.051  73.458  1.00 32.08  ? 225 LEU F CD1 1 
ATOM 4906 C CD2 . LEU D 4 225 ? 103.327 83.318  73.250  1.00 34.78  ? 225 LEU F CD2 1 
ATOM 4907 N N   . LEU D 4 226 ? 101.512 80.213  70.013  1.00 48.32  ? 226 LEU F N   1 
ATOM 4908 C CA  . LEU D 4 226 ? 100.350 80.578  69.214  1.00 42.08  ? 226 LEU F CA  1 
ATOM 4909 C C   . LEU D 4 226 ? 99.405  81.498  69.978  1.00 42.08  ? 226 LEU F C   1 
ATOM 4910 O O   . LEU D 4 226 ? 99.101  82.598  69.511  1.00 51.08  ? 226 LEU F O   1 
ATOM 4911 C CB  . LEU D 4 226 ? 99.601  79.317  68.760  1.00 44.30  ? 226 LEU F CB  1 
ATOM 4912 C CG  . LEU D 4 226 ? 100.324 78.378  67.793  1.00 43.92  ? 226 LEU F CG  1 
ATOM 4913 C CD1 . LEU D 4 226 ? 99.521  77.102  67.611  1.00 45.19  ? 226 LEU F CD1 1 
ATOM 4914 C CD2 . LEU D 4 226 ? 100.571 79.048  66.452  1.00 44.46  ? 226 LEU F CD2 1 
ATOM 4915 N N   . ILE D 4 227 ? 98.934  81.074  71.148  1.00 40.48  ? 227 ILE F N   1 
ATOM 4916 C CA  . ILE D 4 227 ? 97.969  81.831  71.937  1.00 43.45  ? 227 ILE F CA  1 
ATOM 4917 C C   . ILE D 4 227 ? 98.364  81.732  73.402  1.00 36.93  ? 227 ILE F C   1 
ATOM 4918 O O   . ILE D 4 227 ? 98.677  80.642  73.889  1.00 47.06  ? 227 ILE F O   1 
ATOM 4919 C CB  . ILE D 4 227 ? 96.533  81.312  71.724  1.00 47.61  ? 227 ILE F CB  1 
ATOM 4920 C CG1 . ILE D 4 227 ? 95.971  81.857  70.408  1.00 41.17  ? 227 ILE F CG1 1 
ATOM 4921 C CG2 . ILE D 4 227 ? 95.643  81.676  72.911  1.00 46.60  ? 227 ILE F CG2 1 
ATOM 4922 C CD1 . ILE D 4 227 ? 94.642  81.265  70.009  1.00 44.37  ? 227 ILE F CD1 1 
ATOM 4923 N N   . TYR D 4 228 ? 98.341  82.860  74.104  1.00 31.44  ? 228 TYR F N   1 
ATOM 4924 C CA  . TYR D 4 228 ? 98.668  82.911  75.521  1.00 39.36  ? 228 TYR F CA  1 
ATOM 4925 C C   . TYR D 4 228 ? 97.447  83.335  76.326  1.00 41.84  ? 228 TYR F C   1 
ATOM 4926 O O   . TYR D 4 228 ? 96.676  84.197  75.896  1.00 48.11  ? 228 TYR F O   1 
ATOM 4927 C CB  . TYR D 4 228 ? 99.833  83.866  75.790  1.00 40.68  ? 228 TYR F CB  1 
ATOM 4928 C CG  . TYR D 4 228 ? 99.641  85.272  75.278  1.00 40.56  ? 228 TYR F CG  1 
ATOM 4929 C CD1 . TYR D 4 228 ? 99.921  85.597  73.958  1.00 36.52  ? 228 TYR F CD1 1 
ATOM 4930 C CD2 . TYR D 4 228 ? 99.206  86.283  76.123  1.00 35.99  ? 228 TYR F CD2 1 
ATOM 4931 C CE1 . TYR D 4 228 ? 99.759  86.883  73.492  1.00 36.78  ? 228 TYR F CE1 1 
ATOM 4932 C CE2 . TYR D 4 228 ? 99.041  87.571  75.665  1.00 34.84  ? 228 TYR F CE2 1 
ATOM 4933 C CZ  . TYR D 4 228 ? 99.319  87.866  74.350  1.00 39.28  ? 228 TYR F CZ  1 
ATOM 4934 O OH  . TYR D 4 228 ? 99.157  89.149  73.889  1.00 42.62  ? 228 TYR F OH  1 
ATOM 4935 N N   . ARG D 4 229 ? 97.275  82.714  77.493  1.00 35.91  ? 229 ARG F N   1 
ATOM 4936 C CA  . ARG D 4 229 ? 96.125  82.969  78.360  1.00 37.36  ? 229 ARG F CA  1 
ATOM 4937 C C   . ARG D 4 229 ? 94.810  82.762  77.605  1.00 42.19  ? 229 ARG F C   1 
ATOM 4938 O O   . ARG D 4 229 ? 93.856  83.527  77.753  1.00 35.71  ? 229 ARG F O   1 
ATOM 4939 C CB  . ARG D 4 229 ? 96.209  84.365  78.981  1.00 38.85  ? 229 ARG F CB  1 
ATOM 4940 C CG  . ARG D 4 229 ? 97.205  84.436  80.132  1.00 30.43  ? 229 ARG F CG  1 
ATOM 4941 C CD  . ARG D 4 229 ? 97.171  85.766  80.864  1.00 34.47  ? 229 ARG F CD  1 
ATOM 4942 N NE  . ARG D 4 229 ? 98.292  86.629  80.506  1.00 31.20  ? 229 ARG F NE  1 
ATOM 4943 C CZ  . ARG D 4 229 ? 98.226  87.684  79.704  1.00 29.76  ? 229 ARG F CZ  1 
ATOM 4944 N NH1 . ARG D 4 229 ? 97.092  88.058  79.134  1.00 38.15  ? 229 ARG F NH1 1 
ATOM 4945 N NH2 . ARG D 4 229 ? 99.329  88.385  79.468  1.00 34.79  ? 229 ARG F NH2 1 
ATOM 4946 N N   . MET D 4 230 ? 94.798  81.745  76.742  1.00 57.83  ? 230 MET F N   1 
ATOM 4947 C CA  . MET D 4 230 ? 93.606  81.103  76.187  1.00 55.36  ? 230 MET F CA  1 
ATOM 4948 C C   . MET D 4 230 ? 92.793  81.977  75.238  1.00 57.90  ? 230 MET F C   1 
ATOM 4949 O O   . MET D 4 230 ? 91.833  81.488  74.633  1.00 61.94  ? 230 MET F O   1 
ATOM 4950 C CB  . MET D 4 230 ? 92.696  80.592  77.318  1.00 52.96  ? 230 MET F CB  1 
ATOM 4951 C CG  . MET D 4 230 ? 91.862  81.635  78.066  1.00 55.79  ? 230 MET F CG  1 
ATOM 4952 S SD  . MET D 4 230 ? 90.369  80.944  78.811  1.00 68.37  ? 230 MET F SD  1 
ATOM 4953 C CE  . MET D 4 230 ? 89.165  81.168  77.506  1.00 55.21  ? 230 MET F CE  1 
ATOM 4954 N N   . SER D 4 231 ? 93.150  83.251  75.082  1.00 51.30  ? 231 SER F N   1 
ATOM 4955 C CA  . SER D 4 231 ? 92.382  84.132  74.204  1.00 54.38  ? 231 SER F CA  1 
ATOM 4956 C C   . SER D 4 231 ? 93.220  85.066  73.349  1.00 55.08  ? 231 SER F C   1 
ATOM 4957 O O   . SER D 4 231 ? 92.729  85.504  72.303  1.00 50.59  ? 231 SER F O   1 
ATOM 4958 C CB  . SER D 4 231 ? 91.401  84.974  75.026  1.00 53.97  ? 231 SER F CB  1 
ATOM 4959 O OG  . SER D 4 231 ? 90.382  84.168  75.586  1.00 52.76  ? 231 SER F OG  1 
ATOM 4960 N N   . ASN D 4 232 ? 94.451  85.389  73.730  1.00 52.31  ? 232 ASN F N   1 
ATOM 4961 C CA  . ASN D 4 232 ? 95.221  86.438  73.080  1.00 50.43  ? 232 ASN F CA  1 
ATOM 4962 C C   . ASN D 4 232 ? 96.167  85.832  72.053  1.00 48.62  ? 232 ASN F C   1 
ATOM 4963 O O   . ASN D 4 232 ? 96.865  84.858  72.344  1.00 48.27  ? 232 ASN F O   1 
ATOM 4964 C CB  . ASN D 4 232 ? 96.002  87.242  74.117  1.00 47.19  ? 232 ASN F CB  1 
ATOM 4965 C CG  . ASN D 4 232 ? 95.106  87.836  75.180  1.00 47.89  ? 232 ASN F CG  1 
ATOM 4966 O OD1 . ASN D 4 232 ? 95.177  87.462  76.350  1.00 46.58  ? 232 ASN F OD1 1 
ATOM 4967 N ND2 . ASN D 4 232 ? 94.251  88.767  74.778  1.00 50.78  ? 232 ASN F ND2 1 
ATOM 4968 N N   . LEU D 4 233 ? 96.184  86.413  70.858  1.00 60.51  ? 233 LEU F N   1 
ATOM 4969 C CA  . LEU D 4 233 ? 96.996  85.917  69.758  1.00 58.76  ? 233 LEU F CA  1 
ATOM 4970 C C   . LEU D 4 233 ? 98.371  86.571  69.785  1.00 61.57  ? 233 LEU F C   1 
ATOM 4971 O O   . LEU D 4 233 ? 98.493  87.776  70.017  1.00 64.10  ? 233 LEU F O   1 
ATOM 4972 C CB  . LEU D 4 233 ? 96.305  86.198  68.423  1.00 60.83  ? 233 LEU F CB  1 
ATOM 4973 C CG  . LEU D 4 233 ? 96.796  85.435  67.193  1.00 64.71  ? 233 LEU F CG  1 
ATOM 4974 C CD1 . LEU D 4 233 ? 96.585  83.937  67.352  1.00 62.89  ? 233 LEU F CD1 1 
ATOM 4975 C CD2 . LEU D 4 233 ? 96.084  85.947  65.954  1.00 65.02  ? 233 LEU F CD2 1 
ATOM 4976 N N   . ALA D 4 234 ? 99.403  85.767  69.547  1.00 60.76  ? 234 ALA F N   1 
ATOM 4977 C CA  . ALA D 4 234 ? 100.770 86.255  69.611  1.00 60.46  ? 234 ALA F CA  1 
ATOM 4978 C C   . ALA D 4 234 ? 101.126 87.039  68.352  1.00 65.81  ? 234 ALA F C   1 
ATOM 4979 O O   . ALA D 4 234 ? 100.531 86.862  67.286  1.00 68.26  ? 234 ALA F O   1 
ATOM 4980 C CB  . ALA D 4 234 ? 101.746 85.094  69.795  1.00 60.59  ? 234 ALA F CB  1 
ATOM 4981 N N   . SER D 4 235 ? 102.118 87.915  68.488  1.00 73.38  ? 235 SER F N   1 
ATOM 4982 C CA  . SER D 4 235 ? 102.562 88.724  67.363  1.00 71.21  ? 235 SER F CA  1 
ATOM 4983 C C   . SER D 4 235 ? 103.220 87.846  66.307  1.00 72.80  ? 235 SER F C   1 
ATOM 4984 O O   . SER D 4 235 ? 103.978 86.926  66.623  1.00 69.26  ? 235 SER F O   1 
ATOM 4985 C CB  . SER D 4 235 ? 103.541 89.797  67.832  1.00 71.61  ? 235 SER F CB  1 
ATOM 4986 O OG  . SER D 4 235 ? 104.799 89.231  68.150  1.00 72.27  ? 235 SER F OG  1 
ATOM 4987 N N   . GLY D 4 236 ? 102.930 88.140  65.041  1.00 77.90  ? 236 GLY F N   1 
ATOM 4988 C CA  . GLY D 4 236 ? 103.442 87.354  63.941  1.00 76.64  ? 236 GLY F CA  1 
ATOM 4989 C C   . GLY D 4 236 ? 102.669 86.088  63.652  1.00 77.08  ? 236 GLY F C   1 
ATOM 4990 O O   . GLY D 4 236 ? 103.064 85.333  62.754  1.00 76.63  ? 236 GLY F O   1 
ATOM 4991 N N   . VAL D 4 237 ? 101.592 85.828  64.377  1.00 77.25  ? 237 VAL F N   1 
ATOM 4992 C CA  . VAL D 4 237 ? 100.747 84.656  64.159  1.00 77.10  ? 237 VAL F CA  1 
ATOM 4993 C C   . VAL D 4 237 ? 99.568  85.082  63.291  1.00 78.03  ? 237 VAL F C   1 
ATOM 4994 O O   . VAL D 4 237 ? 98.907  86.077  63.618  1.00 77.29  ? 237 VAL F O   1 
ATOM 4995 C CB  . VAL D 4 237 ? 100.257 84.058  65.490  1.00 76.90  ? 237 VAL F CB  1 
ATOM 4996 C CG1 . VAL D 4 237 ? 99.336  82.871  65.243  1.00 76.60  ? 237 VAL F CG1 1 
ATOM 4997 C CG2 . VAL D 4 237 ? 101.441 83.645  66.349  1.00 73.56  ? 237 VAL F CG2 1 
ATOM 4998 N N   . PRO D 4 238 ? 99.274  84.380  62.194  1.00 86.95  ? 238 PRO F N   1 
ATOM 4999 C CA  . PRO D 4 238 ? 98.126  84.769  61.368  1.00 87.00  ? 238 PRO F CA  1 
ATOM 5000 C C   . PRO D 4 238 ? 96.831  84.743  62.165  1.00 86.92  ? 238 PRO F C   1 
ATOM 5001 O O   . PRO D 4 238 ? 96.669  83.969  63.109  1.00 87.06  ? 238 PRO F O   1 
ATOM 5002 C CB  . PRO D 4 238 ? 98.119  83.721  60.250  1.00 87.73  ? 238 PRO F CB  1 
ATOM 5003 C CG  . PRO D 4 238 ? 99.511  83.226  60.184  1.00 87.67  ? 238 PRO F CG  1 
ATOM 5004 C CD  . PRO D 4 238 ? 100.029 83.269  61.587  1.00 86.42  ? 238 PRO F CD  1 
ATOM 5005 N N   . ASP D 4 239 ? 95.904  85.610  61.772  1.00 96.13  ? 239 ASP F N   1 
ATOM 5006 C CA  . ASP D 4 239 ? 94.637  85.790  62.477  1.00 97.09  ? 239 ASP F CA  1 
ATOM 5007 C C   . ASP D 4 239 ? 93.682  84.611  62.321  1.00 97.05  ? 239 ASP F C   1 
ATOM 5008 O O   . ASP D 4 239 ? 92.547  84.723  62.803  1.00 96.86  ? 239 ASP F O   1 
ATOM 5009 C CB  . ASP D 4 239 ? 93.957  87.069  61.987  1.00 96.69  ? 239 ASP F CB  1 
ATOM 5010 C CG  . ASP D 4 239 ? 94.850  88.287  62.112  1.00 97.74  ? 239 ASP F CG  1 
ATOM 5011 O OD1 . ASP D 4 239 ? 95.705  88.310  63.022  1.00 98.46  ? 239 ASP F OD1 1 
ATOM 5012 O OD2 . ASP D 4 239 ? 94.697  89.222  61.298  1.00 97.36  ? 239 ASP F OD2 1 
ATOM 5013 N N   . ARG D 4 240 ? 94.060  83.502  61.688  1.00 97.42  ? 240 ARG F N   1 
ATOM 5014 C CA  . ARG D 4 240 ? 93.170  82.354  61.567  1.00 97.45  ? 240 ARG F CA  1 
ATOM 5015 C C   . ARG D 4 240 ? 93.207  81.442  62.787  1.00 95.73  ? 240 ARG F C   1 
ATOM 5016 O O   . ARG D 4 240 ? 92.457  80.461  62.826  1.00 95.86  ? 240 ARG F O   1 
ATOM 5017 C CB  . ARG D 4 240 ? 93.513  81.547  60.311  1.00 98.25  ? 240 ARG F CB  1 
ATOM 5018 C CG  . ARG D 4 240 ? 94.949  81.052  60.237  1.00 98.04  ? 240 ARG F CG  1 
ATOM 5019 C CD  . ARG D 4 240 ? 95.160  80.154  59.027  1.00 97.27  ? 240 ARG F CD  1 
ATOM 5020 N NE  . ARG D 4 240 ? 96.530  79.658  58.943  1.00 97.85  ? 240 ARG F NE  1 
ATOM 5021 C CZ  . ARG D 4 240 ? 97.525  80.279  58.323  1.00 98.38  ? 240 ARG F CZ  1 
ATOM 5022 N NH1 . ARG D 4 240 ? 97.343  81.433  57.702  1.00 97.02  ? 240 ARG F NH1 1 
ATOM 5023 N NH2 . ARG D 4 240 ? 98.735  79.727  58.327  1.00 98.08  ? 240 ARG F NH2 1 
ATOM 5024 N N   . PHE D 4 241 ? 94.047  81.737  63.775  1.00 85.75  ? 241 PHE F N   1 
ATOM 5025 C CA  . PHE D 4 241 ? 94.142  80.946  64.996  1.00 85.66  ? 241 PHE F CA  1 
ATOM 5026 C C   . PHE D 4 241 ? 93.301  81.605  66.082  1.00 82.86  ? 241 PHE F C   1 
ATOM 5027 O O   . PHE D 4 241 ? 93.481  82.791  66.379  1.00 82.93  ? 241 PHE F O   1 
ATOM 5028 C CB  . PHE D 4 241 ? 95.596  80.816  65.447  1.00 84.39  ? 241 PHE F CB  1 
ATOM 5029 C CG  . PHE D 4 241 ? 96.412  79.888  64.597  1.00 84.27  ? 241 PHE F CG  1 
ATOM 5030 C CD1 . PHE D 4 241 ? 97.027  80.343  63.444  1.00 84.02  ? 241 PHE F CD1 1 
ATOM 5031 C CD2 . PHE D 4 241 ? 96.564  78.559  64.952  1.00 83.51  ? 241 PHE F CD2 1 
ATOM 5032 C CE1 . PHE D 4 241 ? 97.779  79.489  62.661  1.00 84.86  ? 241 PHE F CE1 1 
ATOM 5033 C CE2 . PHE D 4 241 ? 97.315  77.701  64.172  1.00 84.40  ? 241 PHE F CE2 1 
ATOM 5034 C CZ  . PHE D 4 241 ? 97.922  78.167  63.027  1.00 84.90  ? 241 PHE F CZ  1 
ATOM 5035 N N   . SER D 4 242 ? 92.387  80.837  66.669  1.00 75.51  ? 242 SER F N   1 
ATOM 5036 C CA  . SER D 4 242 ? 91.505  81.326  67.717  1.00 76.42  ? 242 SER F CA  1 
ATOM 5037 C C   . SER D 4 242 ? 91.434  80.302  68.840  1.00 78.36  ? 242 SER F C   1 
ATOM 5038 O O   . SER D 4 242 ? 91.532  79.095  68.606  1.00 76.67  ? 242 SER F O   1 
ATOM 5039 C CB  . SER D 4 242 ? 90.095  81.607  67.179  1.00 78.27  ? 242 SER F CB  1 
ATOM 5040 O OG  . SER D 4 242 ? 90.130  82.539  66.112  1.00 77.68  ? 242 SER F OG  1 
ATOM 5041 N N   . GLY D 4 243 ? 91.259  80.798  70.062  1.00 76.61  ? 243 GLY F N   1 
ATOM 5042 C CA  . GLY D 4 243 ? 91.153  79.940  71.226  1.00 74.74  ? 243 GLY F CA  1 
ATOM 5043 C C   . GLY D 4 243 ? 90.053  80.382  72.168  1.00 76.76  ? 243 GLY F C   1 
ATOM 5044 O O   . GLY D 4 243 ? 89.857  81.581  72.383  1.00 76.58  ? 243 GLY F O   1 
ATOM 5045 N N   . SER D 4 244 ? 89.324  79.424  72.734  1.00 78.96  ? 244 SER F N   1 
ATOM 5046 C CA  . SER D 4 244 ? 88.218  79.735  73.628  1.00 77.48  ? 244 SER F CA  1 
ATOM 5047 C C   . SER D 4 244 ? 87.907  78.506  74.468  1.00 75.83  ? 244 SER F C   1 
ATOM 5048 O O   . SER D 4 244 ? 88.403  77.408  74.207  1.00 76.88  ? 244 SER F O   1 
ATOM 5049 C CB  . SER D 4 244 ? 86.982  80.187  72.845  1.00 78.13  ? 244 SER F CB  1 
ATOM 5050 O OG  . SER D 4 244 ? 85.904  80.476  73.716  1.00 77.48  ? 244 SER F OG  1 
ATOM 5051 N N   . GLY D 4 245 ? 87.071  78.708  75.483  1.00 73.13  ? 245 GLY F N   1 
ATOM 5052 C CA  . GLY D 4 245 ? 86.643  77.625  76.346  1.00 74.41  ? 245 GLY F CA  1 
ATOM 5053 C C   . GLY D 4 245 ? 86.715  77.981  77.815  1.00 75.42  ? 245 GLY F C   1 
ATOM 5054 O O   . GLY D 4 245 ? 87.724  78.517  78.285  1.00 76.61  ? 245 GLY F O   1 
ATOM 5055 N N   . SER D 4 246 ? 85.648  77.687  78.552  1.00 75.10  ? 246 SER F N   1 
ATOM 5056 C CA  . SER D 4 246 ? 85.608  77.965  79.979  1.00 74.51  ? 246 SER F CA  1 
ATOM 5057 C C   . SER D 4 246 ? 86.585  77.051  80.720  1.00 73.98  ? 246 SER F C   1 
ATOM 5058 O O   . SER D 4 246 ? 87.289  76.230  80.127  1.00 73.26  ? 246 SER F O   1 
ATOM 5059 C CB  . SER D 4 246 ? 84.187  77.793  80.508  1.00 75.11  ? 246 SER F CB  1 
ATOM 5060 O OG  . SER D 4 246 ? 83.731  76.468  80.307  1.00 76.33  ? 246 SER F OG  1 
ATOM 5061 N N   . GLY D 4 247 ? 86.627  77.203  82.041  1.00 73.27  ? 247 GLY F N   1 
ATOM 5062 C CA  . GLY D 4 247 ? 87.552  76.452  82.868  1.00 71.62  ? 247 GLY F CA  1 
ATOM 5063 C C   . GLY D 4 247 ? 87.447  74.949  82.704  1.00 71.94  ? 247 GLY F C   1 
ATOM 5064 O O   . GLY D 4 247 ? 86.344  74.396  82.648  1.00 71.48  ? 247 GLY F O   1 
ATOM 5065 N N   . THR D 4 248 ? 88.595  74.279  82.631  1.00 70.95  ? 248 THR F N   1 
ATOM 5066 C CA  . THR D 4 248 ? 88.701  72.828  82.502  1.00 70.30  ? 248 THR F CA  1 
ATOM 5067 C C   . THR D 4 248 ? 88.159  72.310  81.175  1.00 70.98  ? 248 THR F C   1 
ATOM 5068 O O   . THR D 4 248 ? 87.967  71.097  81.024  1.00 70.00  ? 248 THR F O   1 
ATOM 5069 C CB  . THR D 4 248 ? 87.987  72.110  83.655  1.00 71.07  ? 248 THR F CB  1 
ATOM 5070 O OG1 . THR D 4 248 ? 86.573  72.311  83.547  1.00 68.56  ? 248 THR F OG1 1 
ATOM 5071 C CG2 . THR D 4 248 ? 88.471  72.632  84.999  1.00 68.75  ? 248 THR F CG2 1 
ATOM 5072 N N   . ALA D 4 249 ? 87.906  73.193  80.207  1.00 74.63  ? 249 ALA F N   1 
ATOM 5073 C CA  . ALA D 4 249 ? 87.415  72.767  78.897  1.00 74.25  ? 249 ALA F CA  1 
ATOM 5074 C C   . ALA D 4 249 ? 87.828  73.841  77.892  1.00 73.10  ? 249 ALA F C   1 
ATOM 5075 O O   . ALA D 4 249 ? 87.186  74.892  77.811  1.00 74.67  ? 249 ALA F O   1 
ATOM 5076 C CB  . ALA D 4 249 ? 85.910  72.562  78.910  1.00 74.22  ? 249 ALA F CB  1 
ATOM 5077 N N   . PHE D 4 250 ? 88.883  73.562  77.131  1.00 67.48  ? 250 PHE F N   1 
ATOM 5078 C CA  . PHE D 4 250 ? 89.485  74.540  76.238  1.00 68.88  ? 250 PHE F CA  1 
ATOM 5079 C C   . PHE D 4 250 ? 89.675  73.932  74.857  1.00 68.19  ? 250 PHE F C   1 
ATOM 5080 O O   . PHE D 4 250 ? 89.739  72.711  74.693  1.00 68.22  ? 250 PHE F O   1 
ATOM 5081 C CB  . PHE D 4 250 ? 90.830  75.028  76.777  1.00 66.99  ? 250 PHE F CB  1 
ATOM 5082 C CG  . PHE D 4 250 ? 90.780  75.477  78.203  1.00 67.26  ? 250 PHE F CG  1 
ATOM 5083 C CD1 . PHE D 4 250 ? 90.503  76.795  78.518  1.00 66.13  ? 250 PHE F CD1 1 
ATOM 5084 C CD2 . PHE D 4 250 ? 91.028  74.585  79.231  1.00 66.84  ? 250 PHE F CD2 1 
ATOM 5085 C CE1 . PHE D 4 250 ? 90.464  77.212  79.833  1.00 65.27  ? 250 PHE F CE1 1 
ATOM 5086 C CE2 . PHE D 4 250 ? 90.991  74.997  80.546  1.00 66.65  ? 250 PHE F CE2 1 
ATOM 5087 C CZ  . PHE D 4 250 ? 90.710  76.312  80.847  1.00 63.26  ? 250 PHE F CZ  1 
ATOM 5088 N N   . THR D 4 251 ? 89.763  74.807  73.857  1.00 72.38  ? 251 THR F N   1 
ATOM 5089 C CA  . THR D 4 251 ? 89.914  74.370  72.479  1.00 72.57  ? 251 THR F CA  1 
ATOM 5090 C C   . THR D 4 251 ? 90.694  75.415  71.696  1.00 73.41  ? 251 THR F C   1 
ATOM 5091 O O   . THR D 4 251 ? 90.744  76.591  72.066  1.00 73.86  ? 251 THR F O   1 
ATOM 5092 C CB  . THR D 4 251 ? 88.554  74.119  71.815  1.00 74.41  ? 251 THR F CB  1 
ATOM 5093 O OG1 . THR D 4 251 ? 88.749  73.731  70.450  1.00 75.16  ? 251 THR F OG1 1 
ATOM 5094 C CG2 . THR D 4 251 ? 87.686  75.371  71.864  1.00 72.25  ? 251 THR F CG2 1 
ATOM 5095 N N   . LEU D 4 252 ? 91.306  74.962  70.605  1.00 73.50  ? 252 LEU F N   1 
ATOM 5096 C CA  . LEU D 4 252 ? 92.009  75.819  69.661  1.00 74.56  ? 252 LEU F CA  1 
ATOM 5097 C C   . LEU D 4 252 ? 91.369  75.645  68.293  1.00 75.70  ? 252 LEU F C   1 
ATOM 5098 O O   . LEU D 4 252 ? 91.074  74.517  67.883  1.00 76.12  ? 252 LEU F O   1 
ATOM 5099 C CB  . LEU D 4 252 ? 93.499  75.473  69.601  1.00 71.61  ? 252 LEU F CB  1 
ATOM 5100 C CG  . LEU D 4 252 ? 94.364  76.366  68.711  1.00 74.43  ? 252 LEU F CG  1 
ATOM 5101 C CD1 . LEU D 4 252 ? 94.627  77.703  69.380  1.00 71.54  ? 252 LEU F CD1 1 
ATOM 5102 C CD2 . LEU D 4 252 ? 95.664  75.669  68.366  1.00 74.23  ? 252 LEU F CD2 1 
ATOM 5103 N N   . THR D 4 253 ? 91.154  76.753  67.591  1.00 80.92  ? 253 THR F N   1 
ATOM 5104 C CA  . THR D 4 253 ? 90.472  76.749  66.305  1.00 82.58  ? 253 THR F CA  1 
ATOM 5105 C C   . THR D 4 253 ? 91.390  77.309  65.228  1.00 83.60  ? 253 THR F C   1 
ATOM 5106 O O   . THR D 4 253 ? 92.103  78.292  65.453  1.00 84.23  ? 253 THR F O   1 
ATOM 5107 C CB  . THR D 4 253 ? 89.177  77.568  66.363  1.00 83.49  ? 253 THR F CB  1 
ATOM 5108 O OG1 . THR D 4 253 ? 88.353  77.094  67.435  1.00 82.93  ? 253 THR F OG1 1 
ATOM 5109 C CG2 . THR D 4 253 ? 88.408  77.454  65.053  1.00 82.02  ? 253 THR F CG2 1 
ATOM 5110 N N   . ILE D 4 254 ? 91.370  76.671  64.060  1.00 96.02  ? 254 ILE F N   1 
ATOM 5111 C CA  . ILE D 4 254 ? 92.099  77.128  62.883  1.00 97.21  ? 254 ILE F CA  1 
ATOM 5112 C C   . ILE D 4 254 ? 91.102  77.261  61.741  1.00 97.61  ? 254 ILE F C   1 
ATOM 5113 O O   . ILE D 4 254 ? 90.341  76.327  61.465  1.00 97.52  ? 254 ILE F O   1 
ATOM 5114 C CB  . ILE D 4 254 ? 93.240  76.164  62.508  1.00 96.44  ? 254 ILE F CB  1 
ATOM 5115 C CG1 . ILE D 4 254 ? 94.224  76.030  63.673  1.00 97.20  ? 254 ILE F CG1 1 
ATOM 5116 C CG2 . ILE D 4 254 ? 93.957  76.655  61.252  1.00 96.40  ? 254 ILE F CG2 1 
ATOM 5117 C CD1 . ILE D 4 254 ? 95.251  74.923  63.506  1.00 98.21  ? 254 ILE F CD1 1 
ATOM 5118 N N   . SER D 4 255 ? 91.107  78.419  61.079  1.00 101.14 ? 255 SER F N   1 
ATOM 5119 C CA  . SER D 4 255 ? 90.151  78.659  60.003  1.00 101.60 ? 255 SER F CA  1 
ATOM 5120 C C   . SER D 4 255 ? 90.496  77.835  58.769  1.00 101.99 ? 255 SER F C   1 
ATOM 5121 O O   . SER D 4 255 ? 89.706  76.992  58.328  1.00 101.73 ? 255 SER F O   1 
ATOM 5122 C CB  . SER D 4 255 ? 90.111  80.150  59.661  1.00 101.85 ? 255 SER F CB  1 
ATOM 5123 O OG  . SER D 4 255 ? 89.093  80.426  58.715  1.00 102.21 ? 255 SER F OG  1 
ATOM 5124 N N   . ARG D 4 256 ? 91.677  78.064  58.200  1.00 106.94 ? 256 ARG F N   1 
ATOM 5125 C CA  . ARG D 4 256 ? 92.123  77.383  56.992  1.00 107.08 ? 256 ARG F CA  1 
ATOM 5126 C C   . ARG D 4 256 ? 93.405  76.621  57.289  1.00 107.42 ? 256 ARG F C   1 
ATOM 5127 O O   . ARG D 4 256 ? 94.369  77.198  57.804  1.00 107.27 ? 256 ARG F O   1 
ATOM 5128 C CB  . ARG D 4 256 ? 92.349  78.381  55.854  1.00 106.88 ? 256 ARG F CB  1 
ATOM 5129 C CG  . ARG D 4 256 ? 91.141  79.251  55.557  1.00 107.42 ? 256 ARG F CG  1 
ATOM 5130 C CD  . ARG D 4 256 ? 91.357  80.109  54.325  1.00 106.65 ? 256 ARG F CD  1 
ATOM 5131 N NE  . ARG D 4 256 ? 90.195  80.939  54.029  1.00 107.11 ? 256 ARG F NE  1 
ATOM 5132 C CZ  . ARG D 4 256 ? 90.059  81.679  52.937  1.00 107.38 ? 256 ARG F CZ  1 
ATOM 5133 N NH1 . ARG D 4 256 ? 90.996  81.715  52.004  1.00 107.39 ? 256 ARG F NH1 1 
ATOM 5134 N NH2 . ARG D 4 256 ? 88.952  82.399  52.777  1.00 107.05 ? 256 ARG F NH2 1 
ATOM 5135 N N   . LEU D 4 257 ? 93.412  75.329  56.963  1.00 110.94 ? 257 LEU F N   1 
ATOM 5136 C CA  . LEU D 4 257 ? 94.569  74.471  57.219  1.00 110.95 ? 257 LEU F CA  1 
ATOM 5137 C C   . LEU D 4 257 ? 95.451  74.415  55.970  1.00 110.62 ? 257 LEU F C   1 
ATOM 5138 O O   . LEU D 4 257 ? 95.527  73.416  55.253  1.00 110.28 ? 257 LEU F O   1 
ATOM 5139 C CB  . LEU D 4 257 ? 94.110  73.088  57.660  1.00 110.68 ? 257 LEU F CB  1 
ATOM 5140 C CG  . LEU D 4 257 ? 93.872  72.999  59.170  1.00 111.10 ? 257 LEU F CG  1 
ATOM 5141 C CD1 . LEU D 4 257 ? 92.840  71.945  59.531  1.00 111.13 ? 257 LEU F CD1 1 
ATOM 5142 C CD2 . LEU D 4 257 ? 95.184  72.717  59.881  1.00 110.22 ? 257 LEU F CD2 1 
ATOM 5143 N N   . GLU D 4 258 ? 96.133  75.530  55.727  1.00 107.80 ? 258 GLU F N   1 
ATOM 5144 C CA  . GLU D 4 258 ? 97.050  75.651  54.602  1.00 107.32 ? 258 GLU F CA  1 
ATOM 5145 C C   . GLU D 4 258 ? 98.396  75.033  54.979  1.00 107.72 ? 258 GLU F C   1 
ATOM 5146 O O   . GLU D 4 258 ? 98.530  74.342  55.992  1.00 108.14 ? 258 GLU F O   1 
ATOM 5147 C CB  . GLU D 4 258 ? 97.188  77.114  54.187  1.00 107.51 ? 258 GLU F CB  1 
ATOM 5148 C CG  . GLU D 4 258 ? 97.799  78.016  55.251  1.00 107.12 ? 258 GLU F CG  1 
ATOM 5149 C CD  . GLU D 4 258 ? 97.992  79.440  54.768  1.00 107.64 ? 258 GLU F CD  1 
ATOM 5150 O OE1 . GLU D 4 258 ? 97.498  79.768  53.669  1.00 108.43 ? 258 GLU F OE1 1 
ATOM 5151 O OE2 . GLU D 4 258 ? 98.640  80.230  55.487  1.00 106.28 ? 258 GLU F OE2 1 
ATOM 5152 N N   . ALA D 4 259 ? 99.414  75.277  54.159  1.00 107.22 ? 259 ALA F N   1 
ATOM 5153 C CA  . ALA D 4 259 ? 100.746 74.773  54.453  1.00 107.53 ? 259 ALA F CA  1 
ATOM 5154 C C   . ALA D 4 259 ? 101.336 75.495  55.662  1.00 107.30 ? 259 ALA F C   1 
ATOM 5155 O O   . ALA D 4 259 ? 100.907 76.589  56.041  1.00 105.93 ? 259 ALA F O   1 
ATOM 5156 C CB  . ALA D 4 259 ? 101.664 74.940  53.242  1.00 106.63 ? 259 ALA F CB  1 
ATOM 5157 N N   . GLU D 4 260 ? 102.332 74.856  56.273  1.00 102.34 ? 260 GLU F N   1 
ATOM 5158 C CA  . GLU D 4 260 ? 103.023 75.331  57.469  1.00 102.16 ? 260 GLU F CA  1 
ATOM 5159 C C   . GLU D 4 260 ? 102.137 75.312  58.709  1.00 101.72 ? 260 GLU F C   1 
ATOM 5160 O O   . GLU D 4 260 ? 102.559 75.795  59.768  1.00 101.22 ? 260 GLU F O   1 
ATOM 5161 C CB  . GLU D 4 260 ? 103.591 76.742  57.273  1.00 102.62 ? 260 GLU F CB  1 
ATOM 5162 C CG  . GLU D 4 260 ? 104.560 76.862  56.104  1.00 102.95 ? 260 GLU F CG  1 
ATOM 5163 C CD  . GLU D 4 260 ? 105.817 76.034  56.296  1.00 103.16 ? 260 GLU F CD  1 
ATOM 5164 O OE1 . GLU D 4 260 ? 106.191 75.777  57.459  1.00 101.58 ? 260 GLU F OE1 1 
ATOM 5165 O OE2 . GLU D 4 260 ? 106.429 75.639  55.282  1.00 102.50 ? 260 GLU F OE2 1 
ATOM 5166 N N   . ASP D 4 261 ? 100.923 74.770  58.615  1.00 99.18  ? 261 ASP F N   1 
ATOM 5167 C CA  . ASP D 4 261 ? 100.048 74.582  59.764  1.00 99.90  ? 261 ASP F CA  1 
ATOM 5168 C C   . ASP D 4 261 ? 100.079 73.152  60.289  1.00 99.47  ? 261 ASP F C   1 
ATOM 5169 O O   . ASP D 4 261 ? 99.300  72.813  61.185  1.00 97.93  ? 261 ASP F O   1 
ATOM 5170 C CB  . ASP D 4 261 ? 98.614  74.968  59.401  1.00 100.12 ? 261 ASP F CB  1 
ATOM 5171 C CG  . ASP D 4 261 ? 98.478  76.431  59.037  1.00 100.50 ? 261 ASP F CG  1 
ATOM 5172 O OD1 . ASP D 4 261 ? 99.477  77.171  59.158  1.00 100.92 ? 261 ASP F OD1 1 
ATOM 5173 O OD2 . ASP D 4 261 ? 97.371  76.842  58.629  1.00 99.28  ? 261 ASP F OD2 1 
ATOM 5174 N N   . VAL D 4 262 ? 100.962 72.312  59.755  1.00 97.79  ? 262 VAL F N   1 
ATOM 5175 C CA  . VAL D 4 262 ? 101.048 70.902  60.114  1.00 97.96  ? 262 VAL F CA  1 
ATOM 5176 C C   . VAL D 4 262 ? 102.157 70.725  61.141  1.00 97.79  ? 262 VAL F C   1 
ATOM 5177 O O   . VAL D 4 262 ? 103.263 71.253  60.972  1.00 97.55  ? 262 VAL F O   1 
ATOM 5178 C CB  . VAL D 4 262 ? 101.307 70.035  58.870  1.00 97.34  ? 262 VAL F CB  1 
ATOM 5179 C CG1 . VAL D 4 262 ? 101.309 68.560  59.237  1.00 97.22  ? 262 VAL F CG1 1 
ATOM 5180 C CG2 . VAL D 4 262 ? 100.253 70.308  57.811  1.00 96.52  ? 262 VAL F CG2 1 
ATOM 5181 N N   . GLY D 4 263 ? 101.861 69.982  62.202  1.00 87.73  ? 263 GLY F N   1 
ATOM 5182 C CA  . GLY D 4 263 ? 102.853 69.713  63.226  1.00 86.73  ? 263 GLY F CA  1 
ATOM 5183 C C   . GLY D 4 263 ? 102.196 69.118  64.454  1.00 87.61  ? 263 GLY F C   1 
ATOM 5184 O O   . GLY D 4 263 ? 101.107 68.548  64.374  1.00 88.44  ? 263 GLY F O   1 
ATOM 5185 N N   . VAL D 4 264 ? 102.874 69.265  65.590  1.00 77.04  ? 264 VAL F N   1 
ATOM 5186 C CA  . VAL D 4 264 ? 102.378 68.789  66.876  1.00 74.43  ? 264 VAL F CA  1 
ATOM 5187 C C   . VAL D 4 264 ? 101.996 69.999  67.716  1.00 73.84  ? 264 VAL F C   1 
ATOM 5188 O O   . VAL D 4 264 ? 102.793 70.933  67.869  1.00 71.37  ? 264 VAL F O   1 
ATOM 5189 C CB  . VAL D 4 264 ? 103.418 67.919  67.603  1.00 73.83  ? 264 VAL F CB  1 
ATOM 5190 C CG1 . VAL D 4 264 ? 102.833 67.369  68.894  1.00 74.00  ? 264 VAL F CG1 1 
ATOM 5191 C CG2 . VAL D 4 264 ? 103.882 66.781  66.715  1.00 73.92  ? 264 VAL F CG2 1 
ATOM 5192 N N   . TYR D 4 265 ? 100.782 69.980  68.257  1.00 65.83  ? 265 TYR F N   1 
ATOM 5193 C CA  . TYR D 4 265 ? 100.266 71.054  69.093  1.00 61.83  ? 265 TYR F CA  1 
ATOM 5194 C C   . TYR D 4 265 ? 100.231 70.601  70.545  1.00 64.95  ? 265 TYR F C   1 
ATOM 5195 O O   . TYR D 4 265 ? 99.811  69.479  70.845  1.00 69.99  ? 265 TYR F O   1 
ATOM 5196 C CB  . TYR D 4 265 ? 98.862  71.473  68.652  1.00 67.26  ? 265 TYR F CB  1 
ATOM 5197 C CG  . TYR D 4 265 ? 98.807  72.110  67.284  1.00 68.15  ? 265 TYR F CG  1 
ATOM 5198 C CD1 . TYR D 4 265 ? 98.687  71.334  66.140  1.00 64.81  ? 265 TYR F CD1 1 
ATOM 5199 C CD2 . TYR D 4 265 ? 98.869  73.489  67.137  1.00 66.28  ? 265 TYR F CD2 1 
ATOM 5200 C CE1 . TYR D 4 265 ? 98.637  71.913  64.888  1.00 67.74  ? 265 TYR F CE1 1 
ATOM 5201 C CE2 . TYR D 4 265 ? 98.820  74.077  65.890  1.00 64.84  ? 265 TYR F CE2 1 
ATOM 5202 C CZ  . TYR D 4 265 ? 98.702  73.284  64.769  1.00 67.50  ? 265 TYR F CZ  1 
ATOM 5203 O OH  . TYR D 4 265 ? 98.653  73.865  63.523  1.00 68.18  ? 265 TYR F OH  1 
ATOM 5204 N N   . TYR D 4 266 ? 100.673 71.477  71.441  1.00 55.45  ? 266 TYR F N   1 
ATOM 5205 C CA  . TYR D 4 266 ? 100.675 71.206  72.869  1.00 55.45  ? 266 TYR F CA  1 
ATOM 5206 C C   . TYR D 4 266 ? 99.907  72.306  73.589  1.00 57.65  ? 266 TYR F C   1 
ATOM 5207 O O   . TYR D 4 266 ? 99.767  73.424  73.087  1.00 57.39  ? 266 TYR F O   1 
ATOM 5208 C CB  . TYR D 4 266 ? 102.102 71.120  73.430  1.00 56.57  ? 266 TYR F CB  1 
ATOM 5209 C CG  . TYR D 4 266 ? 102.993 70.134  72.711  1.00 58.22  ? 266 TYR F CG  1 
ATOM 5210 C CD1 . TYR D 4 266 ? 103.011 68.792  73.070  1.00 60.19  ? 266 TYR F CD1 1 
ATOM 5211 C CD2 . TYR D 4 266 ? 103.823 70.546  71.677  1.00 55.92  ? 266 TYR F CD2 1 
ATOM 5212 C CE1 . TYR D 4 266 ? 103.827 67.888  72.415  1.00 58.43  ? 266 TYR F CE1 1 
ATOM 5213 C CE2 . TYR D 4 266 ? 104.640 69.651  71.018  1.00 58.19  ? 266 TYR F CE2 1 
ATOM 5214 C CZ  . TYR D 4 266 ? 104.641 68.324  71.392  1.00 57.90  ? 266 TYR F CZ  1 
ATOM 5215 O OH  . TYR D 4 266 ? 105.454 67.431  70.735  1.00 56.19  ? 266 TYR F OH  1 
ATOM 5216 N N   . CYS D 4 267 ? 99.396  71.969  74.769  1.00 50.03  ? 267 CYS F N   1 
ATOM 5217 C CA  . CYS D 4 267 ? 98.794  72.939  75.670  1.00 42.57  ? 267 CYS F CA  1 
ATOM 5218 C C   . CYS D 4 267 ? 99.502  72.873  77.014  1.00 50.82  ? 267 CYS F C   1 
ATOM 5219 O O   . CYS D 4 267 ? 99.867  71.790  77.480  1.00 56.09  ? 267 CYS F O   1 
ATOM 5220 C CB  . CYS D 4 267 ? 97.291  72.698  75.850  1.00 45.64  ? 267 CYS F CB  1 
ATOM 5221 S SG  . CYS D 4 267 ? 96.814  71.077  76.489  1.00 58.56  ? 267 CYS F SG  1 
ATOM 5222 N N   . MET D 4 268 ? 99.698  74.036  77.628  1.00 39.27  ? 268 MET F N   1 
ATOM 5223 C CA  . MET D 4 268 ? 100.426 74.153  78.880  1.00 43.76  ? 268 MET F CA  1 
ATOM 5224 C C   . MET D 4 268 ? 99.643  75.047  79.829  1.00 37.46  ? 268 MET F C   1 
ATOM 5225 O O   . MET D 4 268 ? 98.863  75.900  79.399  1.00 36.73  ? 268 MET F O   1 
ATOM 5226 C CB  . MET D 4 268 ? 101.831 74.729  78.653  1.00 39.50  ? 268 MET F CB  1 
ATOM 5227 C CG  . MET D 4 268 ? 102.763 74.627  79.847  1.00 35.66  ? 268 MET F CG  1 
ATOM 5228 S SD  . MET D 4 268 ? 104.194 75.705  79.713  1.00 46.14  ? 268 MET F SD  1 
ATOM 5229 C CE  . MET D 4 268 ? 103.452 77.305  80.011  1.00 35.16  ? 268 MET F CE  1 
ATOM 5230 N N   . GLN D 4 269 ? 99.850  74.836  81.125  1.00 31.02  ? 269 GLN F N   1 
ATOM 5231 C CA  . GLN D 4 269 ? 99.216  75.622  82.170  1.00 32.40  ? 269 GLN F CA  1 
ATOM 5232 C C   . GLN D 4 269 ? 100.280 76.384  82.942  1.00 33.87  ? 269 GLN F C   1 
ATOM 5233 O O   . GLN D 4 269 ? 101.356 75.849  83.219  1.00 40.09  ? 269 GLN F O   1 
ATOM 5234 C CB  . GLN D 4 269 ? 98.413  74.732  83.126  1.00 30.24  ? 269 GLN F CB  1 
ATOM 5235 C CG  . GLN D 4 269 ? 99.244  73.769  83.968  1.00 28.19  ? 269 GLN F CG  1 
ATOM 5236 C CD  . GLN D 4 269 ? 99.676  74.353  85.296  1.00 38.31  ? 269 GLN F CD  1 
ATOM 5237 O OE1 . GLN D 4 269 ? 99.084  75.307  85.792  1.00 41.80  ? 269 GLN F OE1 1 
ATOM 5238 N NE2 . GLN D 4 269 ? 100.716 73.774  85.883  1.00 35.00  ? 269 GLN F NE2 1 
ATOM 5239 N N   . HIS D 4 270 ? 99.985  77.639  83.275  1.00 28.24  ? 270 HIS F N   1 
ATOM 5240 C CA  . HIS D 4 270 ? 100.869 78.453  84.106  1.00 30.27  ? 270 HIS F CA  1 
ATOM 5241 C C   . HIS D 4 270 ? 100.025 79.036  85.236  1.00 30.46  ? 270 HIS F C   1 
ATOM 5242 O O   . HIS D 4 270 ? 99.661  80.212  85.218  1.00 34.45  ? 270 HIS F O   1 
ATOM 5243 C CB  . HIS D 4 270 ? 101.534 79.539  83.263  1.00 25.19  ? 270 HIS F CB  1 
ATOM 5244 C CG  . HIS D 4 270 ? 102.764 80.121  83.882  1.00 31.43  ? 270 HIS F CG  1 
ATOM 5245 N ND1 . HIS D 4 270 ? 103.864 80.489  83.140  1.00 26.27  ? 270 HIS F ND1 1 
ATOM 5246 C CD2 . HIS D 4 270 ? 103.068 80.399  85.171  1.00 31.15  ? 270 HIS F CD2 1 
ATOM 5247 C CE1 . HIS D 4 270 ? 104.794 80.967  83.945  1.00 33.49  ? 270 HIS F CE1 1 
ATOM 5248 N NE2 . HIS D 4 270 ? 104.336 80.925  85.183  1.00 30.29  ? 270 HIS F NE2 1 
ATOM 5249 N N   . LEU D 4 271 ? 99.754  78.216  86.233  1.00 26.30  ? 271 LEU F N   1 
ATOM 5250 C CA  . LEU D 4 271 ? 99.077  78.630  87.456  1.00 34.19  ? 271 LEU F CA  1 
ATOM 5251 C C   . LEU D 4 271 ? 99.799  78.153  88.703  1.00 40.95  ? 271 LEU F C   1 
ATOM 5252 O O   . LEU D 4 271 ? 99.868  78.890  89.689  1.00 37.98  ? 271 LEU F O   1 
ATOM 5253 C CB  . LEU D 4 271 ? 97.632  78.105  87.452  1.00 35.47  ? 271 LEU F CB  1 
ATOM 5254 C CG  . LEU D 4 271 ? 96.793  78.354  88.707  1.00 34.53  ? 271 LEU F CG  1 
ATOM 5255 C CD1 . LEU D 4 271 ? 96.679  79.839  89.009  1.00 26.98  ? 271 LEU F CD1 1 
ATOM 5256 C CD2 . LEU D 4 271 ? 95.421  77.723  88.544  1.00 34.56  ? 271 LEU F CD2 1 
ATOM 5257 N N   . GLU D 4 272 ? 100.345 76.942  88.677  1.00 31.17  ? 272 GLU F N   1 
ATOM 5258 C CA  . GLU D 4 272 ? 101.143 76.390  89.759  1.00 36.24  ? 272 GLU F CA  1 
ATOM 5259 C C   . GLU D 4 272 ? 102.549 76.152  89.233  1.00 41.11  ? 272 GLU F C   1 
ATOM 5260 O O   . GLU D 4 272 ? 102.724 75.691  88.101  1.00 38.49  ? 272 GLU F O   1 
ATOM 5261 C CB  . GLU D 4 272 ? 100.534 75.084  90.283  1.00 41.88  ? 272 GLU F CB  1 
ATOM 5262 C CG  . GLU D 4 272 ? 99.073  75.199  90.715  1.00 42.97  ? 272 GLU F CG  1 
ATOM 5263 C CD  . GLU D 4 272 ? 98.896  75.984  92.003  1.00 44.09  ? 272 GLU F CD  1 
ATOM 5264 O OE1 . GLU D 4 272 ? 99.914  76.328  92.639  1.00 45.79  ? 272 GLU F OE1 1 
ATOM 5265 O OE2 . GLU D 4 272 ? 97.738  76.256  92.380  1.00 32.40  ? 272 GLU F OE2 1 
ATOM 5266 N N   . TYR D 4 273 ? 103.547 76.464  90.059  1.00 40.08  ? 273 TYR F N   1 
ATOM 5267 C CA  . TYR D 4 273 ? 104.912 76.575  89.554  1.00 36.57  ? 273 TYR F CA  1 
ATOM 5268 C C   . TYR D 4 273 ? 105.420 75.325  88.847  1.00 35.53  ? 273 TYR F C   1 
ATOM 5269 O O   . TYR D 4 273 ? 106.118 75.476  87.830  1.00 39.97  ? 273 TYR F O   1 
ATOM 5270 C CB  . TYR D 4 273 ? 105.851 76.987  90.689  1.00 31.23  ? 273 TYR F CB  1 
ATOM 5271 C CG  . TYR D 4 273 ? 106.048 78.483  90.738  1.00 35.80  ? 273 TYR F CG  1 
ATOM 5272 C CD1 . TYR D 4 273 ? 106.822 79.128  89.782  1.00 31.12  ? 273 TYR F CD1 1 
ATOM 5273 C CD2 . TYR D 4 273 ? 105.449 79.253  91.727  1.00 38.12  ? 273 TYR F CD2 1 
ATOM 5274 C CE1 . TYR D 4 273 ? 107.003 80.495  89.814  1.00 35.47  ? 273 TYR F CE1 1 
ATOM 5275 C CE2 . TYR D 4 273 ? 105.626 80.624  91.768  1.00 37.12  ? 273 TYR F CE2 1 
ATOM 5276 C CZ  . TYR D 4 273 ? 106.404 81.240  90.808  1.00 34.76  ? 273 TYR F CZ  1 
ATOM 5277 O OH  . TYR D 4 273 ? 106.584 82.605  90.842  1.00 34.65  ? 273 TYR F OH  1 
ATOM 5278 N N   . PRO D 4 274 ? 105.147 74.099  89.302  1.00 32.84  ? 274 PRO F N   1 
ATOM 5279 C CA  . PRO D 4 274 ? 105.437 72.953  88.431  1.00 35.19  ? 274 PRO F CA  1 
ATOM 5280 C C   . PRO D 4 274 ? 104.576 73.015  87.181  1.00 41.29  ? 274 PRO F C   1 
ATOM 5281 O O   . PRO D 4 274 ? 103.356 72.836  87.254  1.00 48.90  ? 274 PRO F O   1 
ATOM 5282 C CB  . PRO D 4 274 ? 105.101 71.737  89.305  1.00 35.69  ? 274 PRO F CB  1 
ATOM 5283 C CG  . PRO D 4 274 ? 104.229 72.259  90.385  1.00 37.38  ? 274 PRO F CG  1 
ATOM 5284 C CD  . PRO D 4 274 ? 104.668 73.669  90.626  1.00 37.43  ? 274 PRO F CD  1 
ATOM 5285 N N   . LEU D 4 275 ? 105.193 73.274  86.032  1.00 29.65  ? 275 LEU F N   1 
ATOM 5286 C CA  . LEU D 4 275 ? 104.460 73.515  84.796  1.00 32.84  ? 275 LEU F CA  1 
ATOM 5287 C C   . LEU D 4 275 ? 104.361 72.214  84.015  1.00 35.12  ? 275 LEU F C   1 
ATOM 5288 O O   . LEU D 4 275 ? 105.381 71.596  83.697  1.00 40.49  ? 275 LEU F O   1 
ATOM 5289 C CB  . LEU D 4 275 ? 105.148 74.594  83.963  1.00 32.70  ? 275 LEU F CB  1 
ATOM 5290 C CG  . LEU D 4 275 ? 105.366 75.942  84.653  1.00 25.62  ? 275 LEU F CG  1 
ATOM 5291 C CD1 . LEU D 4 275 ? 106.122 76.880  83.741  1.00 28.98  ? 275 LEU F CD1 1 
ATOM 5292 C CD2 . LEU D 4 275 ? 104.049 76.561  85.077  1.00 27.42  ? 275 LEU F CD2 1 
ATOM 5293 N N   . THR D 4 276 ? 103.137 71.805  83.701  1.00 40.53  ? 276 THR F N   1 
ATOM 5294 C CA  . THR D 4 276 ? 102.874 70.528  83.056  1.00 40.77  ? 276 THR F CA  1 
ATOM 5295 C C   . THR D 4 276 ? 102.432 70.763  81.620  1.00 38.27  ? 276 THR F C   1 
ATOM 5296 O O   . THR D 4 276 ? 101.575 71.612  81.361  1.00 39.32  ? 276 THR F O   1 
ATOM 5297 C CB  . THR D 4 276 ? 101.801 69.744  83.815  1.00 42.29  ? 276 THR F CB  1 
ATOM 5298 O OG1 . THR D 4 276 ? 102.139 69.690  85.205  1.00 45.02  ? 276 THR F OG1 1 
ATOM 5299 C CG2 . THR D 4 276 ? 101.691 68.325  83.272  1.00 39.74  ? 276 THR F CG2 1 
ATOM 5300 N N   . PHE D 4 277 ? 103.021 70.014  80.697  1.00 46.19  ? 277 PHE F N   1 
ATOM 5301 C CA  . PHE D 4 277 ? 102.649 70.046  79.293  1.00 46.32  ? 277 PHE F CA  1 
ATOM 5302 C C   . PHE D 4 277 ? 101.667 68.923  78.988  1.00 47.17  ? 277 PHE F C   1 
ATOM 5303 O O   . PHE D 4 277 ? 101.553 67.945  79.730  1.00 46.06  ? 277 PHE F O   1 
ATOM 5304 C CB  . PHE D 4 277 ? 103.885 69.907  78.399  1.00 49.50  ? 277 PHE F CB  1 
ATOM 5305 C CG  . PHE D 4 277 ? 104.711 71.155  78.300  1.00 47.03  ? 277 PHE F CG  1 
ATOM 5306 C CD1 . PHE D 4 277 ? 105.691 71.429  79.235  1.00 46.58  ? 277 PHE F CD1 1 
ATOM 5307 C CD2 . PHE D 4 277 ? 104.514 72.048  77.263  1.00 46.38  ? 277 PHE F CD2 1 
ATOM 5308 C CE1 . PHE D 4 277 ? 106.452 72.573  79.141  1.00 49.05  ? 277 PHE F CE1 1 
ATOM 5309 C CE2 . PHE D 4 277 ? 105.273 73.192  77.167  1.00 44.54  ? 277 PHE F CE2 1 
ATOM 5310 C CZ  . PHE D 4 277 ? 106.243 73.454  78.106  1.00 43.34  ? 277 PHE F CZ  1 
ATOM 5311 N N   . GLY D 4 278 ? 100.949 69.079  77.881  1.00 54.04  ? 278 GLY F N   1 
ATOM 5312 C CA  . GLY D 4 278 ? 100.071 68.032  77.412  1.00 56.63  ? 278 GLY F CA  1 
ATOM 5313 C C   . GLY D 4 278 ? 100.817 66.960  76.642  1.00 61.19  ? 278 GLY F C   1 
ATOM 5314 O O   . GLY D 4 278 ? 101.995 67.092  76.311  1.00 60.51  ? 278 GLY F O   1 
ATOM 5315 N N   . ALA D 4 279 ? 100.103 65.871  76.352  1.00 66.65  ? 279 ALA F N   1 
ATOM 5316 C CA  . ALA D 4 279 ? 100.700 64.779  75.590  1.00 67.51  ? 279 ALA F CA  1 
ATOM 5317 C C   . ALA D 4 279 ? 101.069 65.226  74.181  1.00 69.35  ? 279 ALA F C   1 
ATOM 5318 O O   . ALA D 4 279 ? 102.129 64.856  73.662  1.00 66.07  ? 279 ALA F O   1 
ATOM 5319 C CB  . ALA D 4 279 ? 99.743  63.589  75.544  1.00 65.19  ? 279 ALA F CB  1 
ATOM 5320 N N   . GLY D 4 280 ? 100.208 66.019  73.545  1.00 74.47  ? 280 GLY F N   1 
ATOM 5321 C CA  . GLY D 4 280 ? 100.461 66.516  72.206  1.00 72.87  ? 280 GLY F CA  1 
ATOM 5322 C C   . GLY D 4 280 ? 99.452  66.016  71.194  1.00 73.23  ? 280 GLY F C   1 
ATOM 5323 O O   . GLY D 4 280 ? 98.863  64.947  71.376  1.00 76.14  ? 280 GLY F O   1 
ATOM 5324 N N   . THR D 4 281 ? 99.239  66.778  70.122  1.00 73.93  ? 281 THR F N   1 
ATOM 5325 C CA  . THR D 4 281 ? 98.325  66.393  69.054  1.00 77.96  ? 281 THR F CA  1 
ATOM 5326 C C   . THR D 4 281 ? 99.034  66.559  67.720  1.00 80.70  ? 281 THR F C   1 
ATOM 5327 O O   . THR D 4 281 ? 99.435  67.671  67.367  1.00 79.57  ? 281 THR F O   1 
ATOM 5328 C CB  . THR D 4 281 ? 97.044  67.231  69.085  1.00 80.43  ? 281 THR F CB  1 
ATOM 5329 O OG1 . THR D 4 281 ? 96.344  66.991  70.310  1.00 79.15  ? 281 THR F OG1 1 
ATOM 5330 C CG2 . THR D 4 281 ? 96.140  66.880  67.908  1.00 80.56  ? 281 THR F CG2 1 
ATOM 5331 N N   . LYS D 4 282 ? 99.163  65.465  66.976  1.00 93.63  ? 282 LYS F N   1 
ATOM 5332 C CA  . LYS D 4 282 ? 99.875  65.457  65.707  1.00 93.54  ? 282 LYS F CA  1 
ATOM 5333 C C   . LYS D 4 282 ? 98.886  65.459  64.551  1.00 94.97  ? 282 LYS F C   1 
ATOM 5334 O O   . LYS D 4 282 ? 97.875  64.752  64.581  1.00 94.45  ? 282 LYS F O   1 
ATOM 5335 C CB  . LYS D 4 282 ? 100.794 64.236  65.610  1.00 91.43  ? 282 LYS F CB  1 
ATOM 5336 C CG  . LYS D 4 282 ? 101.471 64.037  64.254  1.00 92.54  ? 282 LYS F CG  1 
ATOM 5337 C CD  . LYS D 4 282 ? 102.392 65.190  63.898  1.00 94.22  ? 282 LYS F CD  1 
ATOM 5338 C CE  . LYS D 4 282 ? 103.065 64.974  62.554  1.00 93.81  ? 282 LYS F CE  1 
ATOM 5339 N NZ  . LYS D 4 282 ? 103.982 66.092  62.204  1.00 93.80  ? 282 LYS F NZ  1 
ATOM 5340 N N   . LEU D 4 283 ? 99.186  66.261  63.535  1.00 101.64 ? 283 LEU F N   1 
ATOM 5341 C CA  . LEU D 4 283 ? 98.394  66.322  62.318  1.00 101.74 ? 283 LEU F CA  1 
ATOM 5342 C C   . LEU D 4 283 ? 99.266  65.909  61.142  1.00 102.29 ? 283 LEU F C   1 
ATOM 5343 O O   . LEU D 4 283 ? 100.456 66.236  61.087  1.00 101.24 ? 283 LEU F O   1 
ATOM 5344 C CB  . LEU D 4 283 ? 97.822  67.727  62.078  1.00 101.02 ? 283 LEU F CB  1 
ATOM 5345 C CG  . LEU D 4 283 ? 96.915  68.293  63.176  1.00 101.84 ? 283 LEU F CG  1 
ATOM 5346 C CD1 . LEU D 4 283 ? 96.522  69.731  62.865  1.00 100.45 ? 283 LEU F CD1 1 
ATOM 5347 C CD2 . LEU D 4 283 ? 95.667  67.438  63.389  1.00 102.17 ? 283 LEU F CD2 1 
ATOM 5348 N N   . GLU D 4 284 ? 98.662  65.196  60.195  1.00 111.90 ? 284 GLU F N   1 
ATOM 5349 C CA  . GLU D 4 284 ? 99.396  64.613  59.081  1.00 112.01 ? 284 GLU F CA  1 
ATOM 5350 C C   . GLU D 4 284 ? 98.594  64.790  57.803  1.00 111.83 ? 284 GLU F C   1 
ATOM 5351 O O   . GLU D 4 284 ? 97.369  64.933  57.831  1.00 111.29 ? 284 GLU F O   1 
ATOM 5352 C CB  . GLU D 4 284 ? 99.670  63.117  59.297  1.00 111.75 ? 284 GLU F CB  1 
ATOM 5353 C CG  . GLU D 4 284 ? 98.411  62.255  59.356  1.00 112.89 ? 284 GLU F CG  1 
ATOM 5354 C CD  . GLU D 4 284 ? 97.646  62.425  60.651  1.00 113.22 ? 284 GLU F CD  1 
ATOM 5355 O OE1 . GLU D 4 284 ? 98.200  63.031  61.591  1.00 112.54 ? 284 GLU F OE1 1 
ATOM 5356 O OE2 . GLU D 4 284 ? 96.491  61.957  60.731  1.00 112.54 ? 284 GLU F OE2 1 
ATOM 5357 N N   . LEU D 4 285 ? 99.298  64.753  56.675  1.00 113.77 ? 285 LEU F N   1 
ATOM 5358 C CA  . LEU D 4 285 ? 98.659  64.864  55.367  1.00 114.24 ? 285 LEU F CA  1 
ATOM 5359 C C   . LEU D 4 285 ? 98.186  63.494  54.873  1.00 113.49 ? 285 LEU F C   1 
ATOM 5360 O O   . LEU D 4 285 ? 97.128  63.376  54.252  1.00 114.00 ? 285 LEU F O   1 
ATOM 5361 C CB  . LEU D 4 285 ? 99.619  65.495  54.352  1.00 113.60 ? 285 LEU F CB  1 
ATOM 5362 C CG  . LEU D 4 285 ? 99.873  66.997  54.504  1.00 113.71 ? 285 LEU F CG  1 
ATOM 5363 C CD1 . LEU D 4 285 ? 101.197 67.410  53.881  1.00 112.69 ? 285 LEU F CD1 1 
ATOM 5364 C CD2 . LEU D 4 285 ? 98.747  67.775  53.873  1.00 113.22 ? 285 LEU F CD2 1 
ATOM 5365 N N   . ALA E 5 147 ? 96.961  114.937 156.896 1.00 119.76 ? 41  ALA D N   1 
ATOM 5366 C CA  . ALA E 5 147 ? 96.106  116.023 156.337 1.00 119.90 ? 41  ALA D CA  1 
ATOM 5367 C C   . ALA E 5 147 ? 96.703  116.564 155.043 1.00 119.37 ? 41  ALA D C   1 
ATOM 5368 O O   . ALA E 5 147 ? 96.090  116.475 153.980 1.00 118.47 ? 41  ALA D O   1 
ATOM 5369 C CB  . ALA E 5 147 ? 95.938  117.141 157.353 1.00 118.87 ? 41  ALA D CB  1 
ATOM 5370 N N   . VAL E 5 148 ? 97.908  117.127 155.141 1.00 122.34 ? 42  VAL D N   1 
ATOM 5371 C CA  . VAL E 5 148 ? 98.565  117.685 153.963 1.00 122.95 ? 42  VAL D CA  1 
ATOM 5372 C C   . VAL E 5 148 ? 98.944  116.574 152.991 1.00 123.09 ? 42  VAL D C   1 
ATOM 5373 O O   . VAL E 5 148 ? 98.722  116.683 151.779 1.00 122.17 ? 42  VAL D O   1 
ATOM 5374 C CB  . VAL E 5 148 ? 99.796  118.512 154.379 1.00 122.90 ? 42  VAL D CB  1 
ATOM 5375 C CG1 . VAL E 5 148 ? 100.474 119.120 153.157 1.00 122.19 ? 42  VAL D CG1 1 
ATOM 5376 C CG2 . VAL E 5 148 ? 99.400  119.598 155.375 1.00 122.11 ? 42  VAL D CG2 1 
ATOM 5377 N N   . SER E 5 149 ? 99.522  115.486 153.508 1.00 123.91 ? 43  SER D N   1 
ATOM 5378 C CA  . SER E 5 149 ? 99.974  114.405 152.639 1.00 123.68 ? 43  SER D CA  1 
ATOM 5379 C C   . SER E 5 149 ? 98.812  113.571 152.115 1.00 123.93 ? 43  SER D C   1 
ATOM 5380 O O   . SER E 5 149 ? 98.913  112.984 151.031 1.00 123.27 ? 43  SER D O   1 
ATOM 5381 C CB  . SER E 5 149 ? 100.964 113.514 153.387 1.00 122.30 ? 43  SER D CB  1 
ATOM 5382 O OG  . SER E 5 149 ? 102.135 114.232 153.731 1.00 121.45 ? 43  SER D OG  1 
ATOM 5383 N N   . GLY E 5 150 ? 97.709  113.505 152.857 1.00 124.67 ? 44  GLY D N   1 
ATOM 5384 C CA  . GLY E 5 150 ? 96.575  112.691 152.471 1.00 123.98 ? 44  GLY D CA  1 
ATOM 5385 C C   . GLY E 5 150 ? 95.648  113.300 151.446 1.00 124.30 ? 44  GLY D C   1 
ATOM 5386 O O   . GLY E 5 150 ? 94.685  112.646 151.039 1.00 123.79 ? 44  GLY D O   1 
ATOM 5387 N N   . VAL E 5 151 ? 95.905  114.537 151.013 1.00 122.27 ? 45  VAL D N   1 
ATOM 5388 C CA  . VAL E 5 151 ? 95.056  115.230 150.055 1.00 122.04 ? 45  VAL D CA  1 
ATOM 5389 C C   . VAL E 5 151 ? 95.832  115.673 148.822 1.00 121.75 ? 45  VAL D C   1 
ATOM 5390 O O   . VAL E 5 151 ? 95.357  115.508 147.693 1.00 121.40 ? 45  VAL D O   1 
ATOM 5391 C CB  . VAL E 5 151 ? 94.356  116.439 150.713 1.00 121.37 ? 45  VAL D CB  1 
ATOM 5392 C CG1 . VAL E 5 151 ? 93.431  117.129 149.719 1.00 121.21 ? 45  VAL D CG1 1 
ATOM 5393 C CG2 . VAL E 5 151 ? 93.586  116.002 151.952 1.00 120.37 ? 45  VAL D CG2 1 
ATOM 5394 N N   . LEU E 5 152 ? 97.023  116.247 149.011 1.00 118.60 ? 46  LEU D N   1 
ATOM 5395 C CA  . LEU E 5 152 ? 97.766  116.796 147.880 1.00 118.16 ? 46  LEU D CA  1 
ATOM 5396 C C   . LEU E 5 152 ? 98.180  115.710 146.896 1.00 117.64 ? 46  LEU D C   1 
ATOM 5397 O O   . LEU E 5 152 ? 98.100  115.907 145.678 1.00 116.90 ? 46  LEU D O   1 
ATOM 5398 C CB  . LEU E 5 152 ? 98.998  117.552 148.377 1.00 118.19 ? 46  LEU D CB  1 
ATOM 5399 C CG  . LEU E 5 152 ? 98.769  118.906 149.051 1.00 118.20 ? 46  LEU D CG  1 
ATOM 5400 C CD1 . LEU E 5 152 ? 100.089 119.462 149.561 1.00 118.04 ? 46  LEU D CD1 1 
ATOM 5401 C CD2 . LEU E 5 152 ? 98.103  119.894 148.102 1.00 117.41 ? 46  LEU D CD2 1 
ATOM 5402 N N   . ILE E 5 153 ? 98.633  114.559 147.398 1.00 115.20 ? 47  ILE D N   1 
ATOM 5403 C CA  . ILE E 5 153 ? 99.226  113.552 146.515 1.00 115.31 ? 47  ILE D CA  1 
ATOM 5404 C C   . ILE E 5 153 ? 98.231  113.072 145.464 1.00 114.49 ? 47  ILE D C   1 
ATOM 5405 O O   . ILE E 5 153 ? 98.554  113.131 144.264 1.00 114.43 ? 47  ILE D O   1 
ATOM 5406 C CB  . ILE E 5 153 ? 99.822  112.406 147.345 1.00 114.48 ? 47  ILE D CB  1 
ATOM 5407 C CG1 . ILE E 5 153 ? 100.878 112.936 148.327 1.00 114.50 ? 47  ILE D CG1 1 
ATOM 5408 C CG2 . ILE E 5 153 ? 100.423 111.345 146.442 1.00 113.90 ? 47  ILE D CG2 1 
ATOM 5409 C CD1 . ILE E 5 153 ? 102.068 113.619 147.678 1.00 114.12 ? 47  ILE D CD1 1 
ATOM 5410 N N   . PRO E 5 154 ? 97.024  112.614 145.814 1.00 111.02 ? 48  PRO D N   1 
ATOM 5411 C CA  . PRO E 5 154 ? 96.062  112.267 144.757 1.00 110.86 ? 48  PRO D CA  1 
ATOM 5412 C C   . PRO E 5 154 ? 95.715  113.445 143.867 1.00 110.97 ? 48  PRO D C   1 
ATOM 5413 O O   . PRO E 5 154 ? 95.495  113.260 142.663 1.00 111.62 ? 48  PRO D O   1 
ATOM 5414 C CB  . PRO E 5 154 ? 94.837  111.768 145.539 1.00 111.01 ? 48  PRO D CB  1 
ATOM 5415 C CG  . PRO E 5 154 ? 95.340  111.440 146.891 1.00 111.09 ? 48  PRO D CG  1 
ATOM 5416 C CD  . PRO E 5 154 ? 96.455  112.394 147.154 1.00 110.52 ? 48  PRO D CD  1 
ATOM 5417 N N   . LEU E 5 155 ? 95.672  114.657 144.424 1.00 108.18 ? 49  LEU D N   1 
ATOM 5418 C CA  . LEU E 5 155 ? 95.356  115.832 143.622 1.00 107.95 ? 49  LEU D CA  1 
ATOM 5419 C C   . LEU E 5 155 ? 96.375  116.019 142.506 1.00 107.87 ? 49  LEU D C   1 
ATOM 5420 O O   . LEU E 5 155 ? 96.012  116.136 141.330 1.00 106.92 ? 49  LEU D O   1 
ATOM 5421 C CB  . LEU E 5 155 ? 95.302  117.071 144.518 1.00 108.25 ? 49  LEU D CB  1 
ATOM 5422 C CG  . LEU E 5 155 ? 95.116  118.433 143.842 1.00 109.09 ? 49  LEU D CG  1 
ATOM 5423 C CD1 . LEU E 5 155 ? 93.716  118.566 143.266 1.00 108.71 ? 49  LEU D CD1 1 
ATOM 5424 C CD2 . LEU E 5 155 ? 95.410  119.558 144.824 1.00 108.23 ? 49  LEU D CD2 1 
ATOM 5425 N N   . VAL E 5 156 ? 97.664  116.036 142.855 1.00 106.96 ? 50  VAL D N   1 
ATOM 5426 C CA  . VAL E 5 156 ? 98.694  116.250 141.844 1.00 106.66 ? 50  VAL D CA  1 
ATOM 5427 C C   . VAL E 5 156 ? 98.753  115.069 140.885 1.00 105.18 ? 50  VAL D C   1 
ATOM 5428 O O   . VAL E 5 156 ? 98.962  115.246 139.678 1.00 105.56 ? 50  VAL D O   1 
ATOM 5429 C CB  . VAL E 5 156 ? 100.059 116.518 142.506 1.00 106.66 ? 50  VAL D CB  1 
ATOM 5430 C CG1 . VAL E 5 156 ? 100.005 117.795 143.333 1.00 106.89 ? 50  VAL D CG1 1 
ATOM 5431 C CG2 . VAL E 5 156 ? 100.497 115.339 143.361 1.00 105.83 ? 50  VAL D CG2 1 
ATOM 5432 N N   . TYR E 5 157 ? 98.568  113.849 141.396 1.00 104.42 ? 51  TYR D N   1 
ATOM 5433 C CA  . TYR E 5 157 ? 98.559  112.684 140.517 1.00 104.56 ? 51  TYR D CA  1 
ATOM 5434 C C   . TYR E 5 157 ? 97.484  112.821 139.444 1.00 105.19 ? 51  TYR D C   1 
ATOM 5435 O O   . TYR E 5 157 ? 97.758  112.676 138.245 1.00 107.95 ? 51  TYR D O   1 
ATOM 5436 C CB  . TYR E 5 157 ? 98.343  111.412 141.337 1.00 104.57 ? 51  TYR D CB  1 
ATOM 5437 C CG  . TYR E 5 157 ? 99.605  110.832 141.937 1.00 105.84 ? 51  TYR D CG  1 
ATOM 5438 C CD1 . TYR E 5 157 ? 100.460 111.614 142.699 1.00 105.77 ? 51  TYR D CD1 1 
ATOM 5439 C CD2 . TYR E 5 157 ? 99.933  109.497 141.751 1.00 106.37 ? 51  TYR D CD2 1 
ATOM 5440 C CE1 . TYR E 5 157 ? 101.611 111.085 143.249 1.00 105.76 ? 51  TYR D CE1 1 
ATOM 5441 C CE2 . TYR E 5 157 ? 101.079 108.959 142.300 1.00 105.77 ? 51  TYR D CE2 1 
ATOM 5442 C CZ  . TYR E 5 157 ? 101.913 109.757 143.048 1.00 105.63 ? 51  TYR D CZ  1 
ATOM 5443 O OH  . TYR E 5 157 ? 103.056 109.225 143.595 1.00 106.10 ? 51  TYR D OH  1 
ATOM 5444 N N   . LEU E 5 158 ? 96.252  113.122 139.856 1.00 101.06 ? 52  LEU D N   1 
ATOM 5445 C CA  . LEU E 5 158 ? 95.163  113.233 138.893 1.00 101.57 ? 52  LEU D CA  1 
ATOM 5446 C C   . LEU E 5 158 ? 95.359  114.431 137.971 1.00 102.23 ? 52  LEU D C   1 
ATOM 5447 O O   . LEU E 5 158 ? 95.013  114.370 136.786 1.00 101.72 ? 52  LEU D O   1 
ATOM 5448 C CB  . LEU E 5 158 ? 93.826  113.327 139.629 1.00 102.24 ? 52  LEU D CB  1 
ATOM 5449 C CG  . LEU E 5 158 ? 92.551  113.136 138.802 1.00 102.73 ? 52  LEU D CG  1 
ATOM 5450 C CD1 . LEU E 5 158 ? 92.530  111.776 138.119 1.00 101.69 ? 52  LEU D CD1 1 
ATOM 5451 C CD2 . LEU E 5 158 ? 91.326  113.308 139.687 1.00 102.15 ? 52  LEU D CD2 1 
ATOM 5452 N N   . VAL E 5 159 ? 95.915  115.528 138.492 1.00 101.47 ? 53  VAL D N   1 
ATOM 5453 C CA  . VAL E 5 159 ? 96.134  116.711 137.662 1.00 101.27 ? 53  VAL D CA  1 
ATOM 5454 C C   . VAL E 5 159 ? 97.119  116.398 136.542 1.00 100.30 ? 53  VAL D C   1 
ATOM 5455 O O   . VAL E 5 159 ? 96.874  116.711 135.369 1.00 100.30 ? 53  VAL D O   1 
ATOM 5456 C CB  . VAL E 5 159 ? 96.616  117.890 138.527 1.00 101.15 ? 53  VAL D CB  1 
ATOM 5457 C CG1 . VAL E 5 159 ? 97.245  118.970 137.659 1.00 100.24 ? 53  VAL D CG1 1 
ATOM 5458 C CG2 . VAL E 5 159 ? 95.460  118.463 139.336 1.00 100.29 ? 53  VAL D CG2 1 
ATOM 5459 N N   . VAL E 5 160 ? 98.254  115.781 136.883 1.00 96.99  ? 54  VAL D N   1 
ATOM 5460 C CA  . VAL E 5 160 ? 99.231  115.452 135.848 1.00 96.40  ? 54  VAL D CA  1 
ATOM 5461 C C   . VAL E 5 160 ? 98.646  114.428 134.886 1.00 96.01  ? 54  VAL D C   1 
ATOM 5462 O O   . VAL E 5 160 ? 98.873  114.498 133.672 1.00 97.68  ? 54  VAL D O   1 
ATOM 5463 C CB  . VAL E 5 160 ? 100.558 114.968 136.467 1.00 96.08  ? 54  VAL D CB  1 
ATOM 5464 C CG1 . VAL E 5 160 ? 101.159 116.050 137.353 1.00 96.35  ? 54  VAL D CG1 1 
ATOM 5465 C CG2 . VAL E 5 160 ? 100.376 113.675 137.242 1.00 96.10  ? 54  VAL D CG2 1 
ATOM 5466 N N   . CYS E 5 161 ? 97.863  113.477 135.402 1.00 97.14  ? 55  CYS D N   1 
ATOM 5467 C CA  . CYS E 5 161 ? 97.236  112.495 134.525 1.00 98.28  ? 55  CYS D CA  1 
ATOM 5468 C C   . CYS E 5 161 ? 96.355  113.174 133.484 1.00 98.95  ? 55  CYS D C   1 
ATOM 5469 O O   . CYS E 5 161 ? 96.469  112.900 132.282 1.00 99.46  ? 55  CYS D O   1 
ATOM 5470 C CB  . CYS E 5 161 ? 96.418  111.504 135.353 1.00 98.53  ? 55  CYS D CB  1 
ATOM 5471 S SG  . CYS E 5 161 ? 95.613  110.215 134.374 1.00 99.66  ? 55  CYS D SG  1 
ATOM 5472 N N   . VAL E 5 162 ? 95.470  114.071 133.925 1.00 97.20  ? 56  VAL D N   1 
ATOM 5473 C CA  . VAL E 5 162 ? 94.535  114.691 132.991 1.00 97.57  ? 56  VAL D CA  1 
ATOM 5474 C C   . VAL E 5 162 ? 95.271  115.608 132.024 1.00 96.73  ? 56  VAL D C   1 
ATOM 5475 O O   . VAL E 5 162 ? 94.951  115.651 130.831 1.00 96.70  ? 56  VAL D O   1 
ATOM 5476 C CB  . VAL E 5 162 ? 93.413  115.436 133.742 1.00 97.03  ? 56  VAL D CB  1 
ATOM 5477 C CG1 . VAL E 5 162 ? 92.587  114.458 134.566 1.00 96.62  ? 56  VAL D CG1 1 
ATOM 5478 C CG2 . VAL E 5 162 ? 93.972  116.551 134.615 1.00 97.07  ? 56  VAL D CG2 1 
ATOM 5479 N N   . VAL E 5 163 ? 96.268  116.353 132.508 1.00 94.55  ? 57  VAL D N   1 
ATOM 5480 C CA  . VAL E 5 163 ? 97.002  117.253 131.620 1.00 94.17  ? 57  VAL D CA  1 
ATOM 5481 C C   . VAL E 5 163 ? 97.717  116.456 130.534 1.00 93.16  ? 57  VAL D C   1 
ATOM 5482 O O   . VAL E 5 163 ? 97.662  116.799 129.344 1.00 92.64  ? 57  VAL D O   1 
ATOM 5483 C CB  . VAL E 5 163 ? 97.985  118.121 132.427 1.00 93.86  ? 57  VAL D CB  1 
ATOM 5484 C CG1 . VAL E 5 163 ? 98.927  118.869 131.496 1.00 92.19  ? 57  VAL D CG1 1 
ATOM 5485 C CG2 . VAL E 5 163 ? 97.224  119.097 133.312 1.00 92.51  ? 57  VAL D CG2 1 
ATOM 5486 N N   . GLY E 5 164 ? 98.398  115.377 130.927 1.00 93.69  ? 58  GLY D N   1 
ATOM 5487 C CA  . GLY E 5 164 ? 99.083  114.555 129.946 1.00 94.13  ? 58  GLY D CA  1 
ATOM 5488 C C   . GLY E 5 164 ? 98.130  113.915 128.957 1.00 93.23  ? 58  GLY D C   1 
ATOM 5489 O O   . GLY E 5 164 ? 98.405  113.872 127.755 1.00 92.66  ? 58  GLY D O   1 
ATOM 5490 N N   . LEU E 5 165 ? 97.000  113.400 129.448 1.00 91.52  ? 59  LEU D N   1 
ATOM 5491 C CA  . LEU E 5 165 ? 96.032  112.789 128.546 1.00 92.57  ? 59  LEU D CA  1 
ATOM 5492 C C   . LEU E 5 165 ? 95.500  113.806 127.548 1.00 93.49  ? 59  LEU D C   1 
ATOM 5493 O O   . LEU E 5 165 ? 95.395  113.513 126.352 1.00 92.57  ? 59  LEU D O   1 
ATOM 5494 C CB  . LEU E 5 165 ? 94.886  112.169 129.345 1.00 92.48  ? 59  LEU D CB  1 
ATOM 5495 C CG  . LEU E 5 165 ? 95.197  110.864 130.081 1.00 92.82  ? 59  LEU D CG  1 
ATOM 5496 C CD1 . LEU E 5 165 ? 94.020  110.458 130.951 1.00 92.03  ? 59  LEU D CD1 1 
ATOM 5497 C CD2 . LEU E 5 165 ? 95.549  109.750 129.104 1.00 92.17  ? 59  LEU D CD2 1 
ATOM 5498 N N   . LEU E 5 166 ? 95.178  115.014 128.014 1.00 91.80  ? 60  LEU D N   1 
ATOM 5499 C CA  . LEU E 5 166 ? 94.688  116.051 127.113 1.00 90.34  ? 60  LEU D CA  1 
ATOM 5500 C C   . LEU E 5 166 ? 95.724  116.380 126.047 1.00 90.27  ? 60  LEU D C   1 
ATOM 5501 O O   . LEU E 5 166 ? 95.413  116.414 124.849 1.00 90.38  ? 60  LEU D O   1 
ATOM 5502 C CB  . LEU E 5 166 ? 94.322  117.300 127.915 1.00 90.19  ? 60  LEU D CB  1 
ATOM 5503 C CG  . LEU E 5 166 ? 93.915  118.547 127.127 1.00 90.79  ? 60  LEU D CG  1 
ATOM 5504 C CD1 . LEU E 5 166 ? 92.658  118.288 126.311 1.00 90.69  ? 60  LEU D CD1 1 
ATOM 5505 C CD2 . LEU E 5 166 ? 93.717  119.727 128.067 1.00 89.87  ? 60  LEU D CD2 1 
ATOM 5506 N N   . GLY E 5 167 ? 96.969  116.620 126.464 1.00 89.64  ? 61  GLY D N   1 
ATOM 5507 C CA  . GLY E 5 167 ? 97.993  116.991 125.499 1.00 88.81  ? 61  GLY D CA  1 
ATOM 5508 C C   . GLY E 5 167 ? 98.245  115.902 124.474 1.00 88.08  ? 61  GLY D C   1 
ATOM 5509 O O   . GLY E 5 167 ? 98.304  116.163 123.267 1.00 88.92  ? 61  GLY D O   1 
ATOM 5510 N N   . ASN E 5 168 ? 98.386  114.660 124.940 1.00 84.62  ? 62  ASN D N   1 
ATOM 5511 C CA  . ASN E 5 168 ? 98.667  113.563 124.022 1.00 83.46  ? 62  ASN D CA  1 
ATOM 5512 C C   . ASN E 5 168 ? 97.488  113.298 123.096 1.00 83.55  ? 62  ASN D C   1 
ATOM 5513 O O   . ASN E 5 168 ? 97.683  113.001 121.913 1.00 84.31  ? 62  ASN D O   1 
ATOM 5514 C CB  . ASN E 5 168 ? 99.034  112.307 124.807 1.00 85.19  ? 62  ASN D CB  1 
ATOM 5515 C CG  . ASN E 5 168 ? 100.454 112.345 125.326 1.00 85.42  ? 62  ASN D CG  1 
ATOM 5516 O OD1 . ASN E 5 168 ? 101.392 111.978 124.620 1.00 84.61  ? 62  ASN D OD1 1 
ATOM 5517 N ND2 . ASN E 5 168 ? 100.623 112.795 126.563 1.00 85.80  ? 62  ASN D ND2 1 
ATOM 5518 N N   . SER E 5 169 ? 96.258  113.392 123.608 1.00 87.91  ? 63  SER D N   1 
ATOM 5519 C CA  . SER E 5 169 ? 95.093  113.207 122.752 1.00 88.27  ? 63  SER D CA  1 
ATOM 5520 C C   . SER E 5 169 ? 95.031  114.281 121.677 1.00 87.69  ? 63  SER D C   1 
ATOM 5521 O O   . SER E 5 169 ? 94.737  113.988 120.512 1.00 88.29  ? 63  SER D O   1 
ATOM 5522 C CB  . SER E 5 169 ? 93.819  113.221 123.595 1.00 88.82  ? 63  SER D CB  1 
ATOM 5523 O OG  . SER E 5 169 ? 93.717  114.425 124.333 1.00 88.87  ? 63  SER D OG  1 
ATOM 5524 N N   . LEU E 5 170 ? 95.312  115.532 122.045 1.00 86.37  ? 64  LEU D N   1 
ATOM 5525 C CA  . LEU E 5 170 ? 95.305  116.607 121.059 1.00 85.82  ? 64  LEU D CA  1 
ATOM 5526 C C   . LEU E 5 170 ? 96.360  116.364 119.986 1.00 87.75  ? 64  LEU D C   1 
ATOM 5527 O O   . LEU E 5 170 ? 96.091  116.509 118.786 1.00 88.29  ? 64  LEU D O   1 
ATOM 5528 C CB  . LEU E 5 170 ? 95.537  117.947 121.757 1.00 86.07  ? 64  LEU D CB  1 
ATOM 5529 C CG  . LEU E 5 170 ? 95.225  119.215 120.962 1.00 87.88  ? 64  LEU D CG  1 
ATOM 5530 C CD1 . LEU E 5 170 ? 93.736  119.326 120.681 1.00 87.22  ? 64  LEU D CD1 1 
ATOM 5531 C CD2 . LEU E 5 170 ? 95.724  120.440 121.711 1.00 86.73  ? 64  LEU D CD2 1 
ATOM 5532 N N   . VAL E 5 171 ? 97.570  115.980 120.401 1.00 85.07  ? 65  VAL D N   1 
ATOM 5533 C CA  . VAL E 5 171 ? 98.638  115.739 119.433 1.00 82.35  ? 65  VAL D CA  1 
ATOM 5534 C C   . VAL E 5 171 ? 98.275  114.581 118.512 1.00 81.58  ? 65  VAL D C   1 
ATOM 5535 O O   . VAL E 5 171 ? 98.472  114.653 117.292 1.00 84.59  ? 65  VAL D O   1 
ATOM 5536 C CB  . VAL E 5 171 ? 99.970  115.489 120.164 1.00 82.75  ? 65  VAL D CB  1 
ATOM 5537 C CG1 . VAL E 5 171 ? 101.018 114.939 119.206 1.00 80.59  ? 65  VAL D CG1 1 
ATOM 5538 C CG2 . VAL E 5 171 ? 100.456 116.774 120.813 1.00 81.93  ? 65  VAL D CG2 1 
ATOM 5539 N N   . ILE E 5 172 ? 97.747  113.494 119.077 1.00 88.03  ? 66  ILE D N   1 
ATOM 5540 C CA  . ILE E 5 172 ? 97.382  112.337 118.266 1.00 88.73  ? 66  ILE D CA  1 
ATOM 5541 C C   . ILE E 5 172 ? 96.294  112.713 117.271 1.00 90.48  ? 66  ILE D C   1 
ATOM 5542 O O   . ILE E 5 172 ? 96.346  112.323 116.101 1.00 91.60  ? 66  ILE D O   1 
ATOM 5543 C CB  . ILE E 5 172 ? 96.949  111.165 119.167 1.00 89.82  ? 66  ILE D CB  1 
ATOM 5544 C CG1 . ILE E 5 172 ? 98.167  110.587 119.896 1.00 89.22  ? 66  ILE D CG1 1 
ATOM 5545 C CG2 . ILE E 5 172 ? 96.237  110.086 118.346 1.00 89.92  ? 66  ILE D CG2 1 
ATOM 5546 C CD1 . ILE E 5 172 ? 97.834  109.542 120.946 1.00 88.86  ? 66  ILE D CD1 1 
ATOM 5547 N N   . TYR E 5 173 ? 95.291  113.471 117.717 1.00 92.63  ? 67  TYR D N   1 
ATOM 5548 C CA  . TYR E 5 173 ? 94.219  113.880 116.817 1.00 92.49  ? 67  TYR D CA  1 
ATOM 5549 C C   . TYR E 5 173 ? 94.755  114.733 115.675 1.00 93.03  ? 67  TYR D C   1 
ATOM 5550 O O   . TYR E 5 173 ? 94.399  114.520 114.508 1.00 94.49  ? 67  TYR D O   1 
ATOM 5551 C CB  . TYR E 5 173 ? 93.150  114.635 117.607 1.00 94.27  ? 67  TYR D CB  1 
ATOM 5552 C CG  . TYR E 5 173 ? 92.320  115.596 116.792 1.00 93.95  ? 67  TYR D CG  1 
ATOM 5553 C CD1 . TYR E 5 173 ? 91.335  115.137 115.929 1.00 94.05  ? 67  TYR D CD1 1 
ATOM 5554 C CD2 . TYR E 5 173 ? 92.509  116.968 116.901 1.00 93.40  ? 67  TYR D CD2 1 
ATOM 5555 C CE1 . TYR E 5 173 ? 90.570  116.016 115.187 1.00 94.22  ? 67  TYR D CE1 1 
ATOM 5556 C CE2 . TYR E 5 173 ? 91.749  117.854 116.165 1.00 94.40  ? 67  TYR D CE2 1 
ATOM 5557 C CZ  . TYR E 5 173 ? 90.781  117.374 115.311 1.00 95.02  ? 67  TYR D CZ  1 
ATOM 5558 O OH  . TYR E 5 173 ? 90.022  118.255 114.576 1.00 94.72  ? 67  TYR D OH  1 
ATOM 5559 N N   . VAL E 5 174 ? 95.622  115.699 115.989 1.00 89.14  ? 68  VAL D N   1 
ATOM 5560 C CA  . VAL E 5 174 ? 96.164  116.567 114.947 1.00 89.16  ? 68  VAL D CA  1 
ATOM 5561 C C   . VAL E 5 174 ? 96.962  115.747 113.942 1.00 87.72  ? 68  VAL D C   1 
ATOM 5562 O O   . VAL E 5 174 ? 96.786  115.882 112.726 1.00 87.82  ? 68  VAL D O   1 
ATOM 5563 C CB  . VAL E 5 174 ? 97.016  117.687 115.571 1.00 87.91  ? 68  VAL D CB  1 
ATOM 5564 C CG1 . VAL E 5 174 ? 97.767  118.450 114.492 1.00 85.95  ? 68  VAL D CG1 1 
ATOM 5565 C CG2 . VAL E 5 174 ? 96.139  118.631 116.379 1.00 85.72  ? 68  VAL D CG2 1 
ATOM 5566 N N   . VAL E 5 175 ? 97.833  114.863 114.434 1.00 88.36  ? 69  VAL D N   1 
ATOM 5567 C CA  . VAL E 5 175 ? 98.652  114.056 113.532 1.00 88.82  ? 69  VAL D CA  1 
ATOM 5568 C C   . VAL E 5 175 ? 97.774  113.150 112.682 1.00 89.24  ? 69  VAL D C   1 
ATOM 5569 O O   . VAL E 5 175 ? 98.045  112.934 111.496 1.00 88.92  ? 69  VAL D O   1 
ATOM 5570 C CB  . VAL E 5 175 ? 99.687  113.241 114.329 1.00 89.96  ? 69  VAL D CB  1 
ATOM 5571 C CG1 . VAL E 5 175 ? 100.431 112.277 113.411 1.00 87.50  ? 69  VAL D CG1 1 
ATOM 5572 C CG2 . VAL E 5 175 ? 100.664 114.162 115.027 1.00 88.42  ? 69  VAL D CG2 1 
ATOM 5573 N N   . LEU E 5 176 ? 96.715  112.597 113.273 1.00 95.86  ? 70  LEU D N   1 
ATOM 5574 C CA  . LEU E 5 176 ? 95.916  111.602 112.572 1.00 96.89  ? 70  LEU D CA  1 
ATOM 5575 C C   . LEU E 5 176 ? 95.025  112.234 111.511 1.00 97.02  ? 70  LEU D C   1 
ATOM 5576 O O   . LEU E 5 176 ? 94.805  111.629 110.456 1.00 96.07  ? 70  LEU D O   1 
ATOM 5577 C CB  . LEU E 5 176 ? 95.074  110.816 113.578 1.00 94.85  ? 70  LEU D CB  1 
ATOM 5578 C CG  . LEU E 5 176 ? 94.617  109.415 113.165 1.00 96.21  ? 70  LEU D CG  1 
ATOM 5579 C CD1 . LEU E 5 176 ? 95.800  108.462 113.061 1.00 95.53  ? 70  LEU D CD1 1 
ATOM 5580 C CD2 . LEU E 5 176 ? 93.584  108.886 114.149 1.00 95.51  ? 70  LEU D CD2 1 
ATOM 5581 N N   . ARG E 5 177 ? 94.506  113.438 111.760 1.00 97.00  ? 71  ARG D N   1 
ATOM 5582 C CA  . ARG E 5 177 ? 93.567  114.064 110.832 1.00 95.06  ? 71  ARG D CA  1 
ATOM 5583 C C   . ARG E 5 177 ? 94.220  115.129 109.957 1.00 95.21  ? 71  ARG D C   1 
ATOM 5584 O O   . ARG E 5 177 ? 94.159  115.041 108.728 1.00 96.18  ? 71  ARG D O   1 
ATOM 5585 C CB  . ARG E 5 177 ? 92.382  114.654 111.611 1.00 95.66  ? 71  ARG D CB  1 
ATOM 5586 C CG  . ARG E 5 177 ? 91.527  113.606 112.327 1.00 96.81  ? 71  ARG D CG  1 
ATOM 5587 C CD  . ARG E 5 177 ? 90.946  112.578 111.358 1.00 97.95  ? 71  ARG D CD  1 
ATOM 5588 N NE  . ARG E 5 177 ? 90.174  111.538 112.026 1.00 98.50  ? 71  ARG D NE  1 
ATOM 5589 C CZ  . ARG E 5 177 ? 89.760  110.422 111.440 1.00 97.56  ? 71  ARG D CZ  1 
ATOM 5590 N NH1 . ARG E 5 177 ? 90.026  110.167 110.169 1.00 95.48  ? 71  ARG D NH1 1 
ATOM 5591 N NH2 . ARG E 5 177 ? 89.064  109.538 112.148 1.00 96.28  ? 71  ARG D NH2 1 
ATOM 5592 N N   . HIS E 5 178 ? 94.856  116.131 110.560 1.00 93.52  ? 72  HIS D N   1 
ATOM 5593 C CA  . HIS E 5 178 ? 95.353  117.273 109.804 1.00 92.61  ? 72  HIS D CA  1 
ATOM 5594 C C   . HIS E 5 178 ? 96.688  117.003 109.115 1.00 92.43  ? 72  HIS D C   1 
ATOM 5595 O O   . HIS E 5 178 ? 97.370  117.956 108.723 1.00 92.80  ? 72  HIS D O   1 
ATOM 5596 C CB  . HIS E 5 178 ? 95.466  118.492 110.719 1.00 91.39  ? 72  HIS D CB  1 
ATOM 5597 C CG  . HIS E 5 178 ? 94.171  118.877 111.362 1.00 92.34  ? 72  HIS D CG  1 
ATOM 5598 N ND1 . HIS E 5 178 ? 93.900  118.639 112.692 1.00 93.60  ? 72  HIS D ND1 1 
ATOM 5599 C CD2 . HIS E 5 178 ? 93.064  119.469 110.853 1.00 93.35  ? 72  HIS D CD2 1 
ATOM 5600 C CE1 . HIS E 5 178 ? 92.688  119.079 112.978 1.00 93.05  ? 72  HIS D CE1 1 
ATOM 5601 N NE2 . HIS E 5 178 ? 92.159  119.588 111.880 1.00 93.80  ? 72  HIS D NE2 1 
ATOM 5602 N N   . THR E 5 179 ? 97.073  115.738 108.962 1.00 89.94  ? 73  THR D N   1 
ATOM 5603 C CA  . THR E 5 179 ? 98.249  115.352 108.195 1.00 88.34  ? 73  THR D CA  1 
ATOM 5604 C C   . THR E 5 179 ? 97.832  114.301 107.178 1.00 88.44  ? 73  THR D C   1 
ATOM 5605 O O   . THR E 5 179 ? 97.102  113.364 107.517 1.00 88.24  ? 73  THR D O   1 
ATOM 5606 C CB  . THR E 5 179 ? 99.357  114.804 109.101 1.00 90.04  ? 73  THR D CB  1 
ATOM 5607 O OG1 . THR E 5 179 ? 99.754  115.811 110.039 1.00 89.00  ? 73  THR D OG1 1 
ATOM 5608 C CG2 . THR E 5 179 ? 100.562 114.381 108.279 1.00 88.77  ? 73  THR D CG2 1 
ATOM 5609 N N   . ALA E 5 180 ? 98.292  114.459 105.938 1.00 85.49  ? 74  ALA D N   1 
ATOM 5610 C CA  . ALA E 5 180 ? 97.905  113.580 104.842 1.00 84.99  ? 74  ALA D CA  1 
ATOM 5611 C C   . ALA E 5 180 ? 99.088  112.856 104.222 1.00 84.02  ? 74  ALA D C   1 
ATOM 5612 O O   . ALA E 5 180 ? 99.042  111.630 104.061 1.00 85.00  ? 74  ALA D O   1 
ATOM 5613 C CB  . ALA E 5 180 ? 97.167  114.388 103.763 1.00 81.70  ? 74  ALA D CB  1 
ATOM 5614 N N   . SER E 5 181 ? 100.148 113.574 103.871 1.00 85.30  ? 75  SER D N   1 
ATOM 5615 C CA  . SER E 5 181 ? 101.252 112.957 103.154 1.00 86.88  ? 75  SER D CA  1 
ATOM 5616 C C   . SER E 5 181 ? 101.953 111.927 104.041 1.00 86.59  ? 75  SER D C   1 
ATOM 5617 O O   . SER E 5 181 ? 102.142 112.167 105.238 1.00 82.90  ? 75  SER D O   1 
ATOM 5618 C CB  . SER E 5 181 ? 102.253 114.016 102.699 1.00 83.88  ? 75  SER D CB  1 
ATOM 5619 O OG  . SER E 5 181 ? 102.728 114.767 103.800 1.00 86.65  ? 75  SER D OG  1 
ATOM 5620 N N   . PRO E 5 182 ? 102.344 110.774 103.493 1.00 82.71  ? 76  PRO D N   1 
ATOM 5621 C CA  . PRO E 5 182 ? 103.122 109.817 104.289 1.00 82.60  ? 76  PRO D CA  1 
ATOM 5622 C C   . PRO E 5 182 ? 104.455 110.411 104.726 1.00 82.34  ? 76  PRO D C   1 
ATOM 5623 O O   . PRO E 5 182 ? 105.058 111.225 104.024 1.00 79.51  ? 76  PRO D O   1 
ATOM 5624 C CB  . PRO E 5 182 ? 103.318 108.633 103.332 1.00 81.48  ? 76  PRO D CB  1 
ATOM 5625 C CG  . PRO E 5 182 ? 102.236 108.764 102.326 1.00 78.46  ? 76  PRO D CG  1 
ATOM 5626 C CD  . PRO E 5 182 ? 101.997 110.228 102.168 1.00 78.88  ? 76  PRO D CD  1 
ATOM 5627 N N   . SER E 5 183 ? 104.911 109.994 105.905 1.00 91.50  ? 77  SER D N   1 
ATOM 5628 C CA  . SER E 5 183 ? 106.145 110.507 106.489 1.00 90.19  ? 77  SER D CA  1 
ATOM 5629 C C   . SER E 5 183 ? 106.621 109.529 107.556 1.00 90.65  ? 77  SER D C   1 
ATOM 5630 O O   . SER E 5 183 ? 105.972 108.517 107.835 1.00 92.13  ? 77  SER D O   1 
ATOM 5631 C CB  . SER E 5 183 ? 105.941 111.907 107.072 1.00 90.63  ? 77  SER D CB  1 
ATOM 5632 O OG  . SER E 5 183 ? 107.070 112.332 107.812 1.00 90.95  ? 77  SER D OG  1 
ATOM 5633 N N   . VAL E 5 184 ? 107.771 109.842 108.150 1.00 91.49  ? 78  VAL D N   1 
ATOM 5634 C CA  . VAL E 5 184 ? 108.365 109.032 109.202 1.00 91.97  ? 78  VAL D CA  1 
ATOM 5635 C C   . VAL E 5 184 ? 108.418 109.781 110.528 1.00 91.91  ? 78  VAL D C   1 
ATOM 5636 O O   . VAL E 5 184 ? 108.188 109.192 111.587 1.00 92.43  ? 78  VAL D O   1 
ATOM 5637 C CB  . VAL E 5 184 ? 109.771 108.545 108.788 1.00 92.43  ? 78  VAL D CB  1 
ATOM 5638 C CG1 . VAL E 5 184 ? 109.669 107.558 107.640 1.00 92.97  ? 78  VAL D CG1 1 
ATOM 5639 C CG2 . VAL E 5 184 ? 110.665 109.717 108.409 1.00 91.14  ? 78  VAL D CG2 1 
ATOM 5640 N N   . THR E 5 185 ? 108.722 111.080 110.493 1.00 86.03  ? 79  THR D N   1 
ATOM 5641 C CA  . THR E 5 185 ? 108.717 111.867 111.720 1.00 85.65  ? 79  THR D CA  1 
ATOM 5642 C C   . THR E 5 185 ? 107.347 111.828 112.380 1.00 86.90  ? 79  THR D C   1 
ATOM 5643 O O   . THR E 5 185 ? 107.239 111.765 113.610 1.00 88.50  ? 79  THR D O   1 
ATOM 5644 C CB  . THR E 5 185 ? 109.128 113.309 111.418 1.00 86.18  ? 79  THR D CB  1 
ATOM 5645 O OG1 . THR E 5 185 ? 110.420 113.318 110.800 1.00 86.67  ? 79  THR D OG1 1 
ATOM 5646 C CG2 . THR E 5 185 ? 109.178 114.139 112.692 1.00 86.99  ? 79  THR D CG2 1 
ATOM 5647 N N   . ASN E 5 186 ? 106.285 111.865 111.574 1.00 87.67  ? 80  ASN D N   1 
ATOM 5648 C CA  . ASN E 5 186 ? 104.940 111.747 112.122 1.00 89.08  ? 80  ASN D CA  1 
ATOM 5649 C C   . ASN E 5 186 ? 104.733 110.386 112.772 1.00 91.16  ? 80  ASN D C   1 
ATOM 5650 O O   . ASN E 5 186 ? 104.074 110.281 113.811 1.00 91.78  ? 80  ASN D O   1 
ATOM 5651 C CB  . ASN E 5 186 ? 103.908 111.986 111.023 1.00 90.02  ? 80  ASN D CB  1 
ATOM 5652 C CG  . ASN E 5 186 ? 104.026 113.365 110.409 1.00 91.39  ? 80  ASN D CG  1 
ATOM 5653 O OD1 . ASN E 5 186 ? 104.403 114.325 111.080 1.00 91.42  ? 80  ASN D OD1 1 
ATOM 5654 N ND2 . ASN E 5 186 ? 103.710 113.470 109.125 1.00 90.74  ? 80  ASN D ND2 1 
ATOM 5655 N N   . VAL E 5 187 ? 105.291 109.330 112.176 1.00 88.02  ? 81  VAL D N   1 
ATOM 5656 C CA  . VAL E 5 187 ? 105.198 108.002 112.779 1.00 88.05  ? 81  VAL D CA  1 
ATOM 5657 C C   . VAL E 5 187 ? 105.869 107.996 114.147 1.00 87.22  ? 81  VAL D C   1 
ATOM 5658 O O   . VAL E 5 187 ? 105.323 107.476 115.129 1.00 87.11  ? 81  VAL D O   1 
ATOM 5659 C CB  . VAL E 5 187 ? 105.817 106.948 111.843 1.00 87.33  ? 81  VAL D CB  1 
ATOM 5660 C CG1 . VAL E 5 187 ? 106.002 105.623 112.570 1.00 86.74  ? 81  VAL D CG1 1 
ATOM 5661 C CG2 . VAL E 5 187 ? 104.957 106.769 110.601 1.00 87.78  ? 81  VAL D CG2 1 
ATOM 5662 N N   . TYR E 5 188 ? 107.070 108.572 114.228 1.00 82.31  ? 82  TYR D N   1 
ATOM 5663 C CA  . TYR E 5 188 ? 107.783 108.619 115.502 1.00 81.96  ? 82  TYR D CA  1 
ATOM 5664 C C   . TYR E 5 188 ? 106.997 109.405 116.546 1.00 83.38  ? 82  TYR D C   1 
ATOM 5665 O O   . TYR E 5 188 ? 106.882 108.979 117.704 1.00 85.32  ? 82  TYR D O   1 
ATOM 5666 C CB  . TYR E 5 188 ? 109.161 109.245 115.303 1.00 80.76  ? 82  TYR D CB  1 
ATOM 5667 C CG  . TYR E 5 188 ? 110.183 108.344 114.652 1.00 81.80  ? 82  TYR D CG  1 
ATOM 5668 C CD1 . TYR E 5 188 ? 109.892 107.645 113.491 1.00 83.26  ? 82  TYR D CD1 1 
ATOM 5669 C CD2 . TYR E 5 188 ? 111.452 108.216 115.189 1.00 81.23  ? 82  TYR D CD2 1 
ATOM 5670 C CE1 . TYR E 5 188 ? 110.832 106.831 112.894 1.00 83.95  ? 82  TYR D CE1 1 
ATOM 5671 C CE2 . TYR E 5 188 ? 112.398 107.410 114.600 1.00 81.74  ? 82  TYR D CE2 1 
ATOM 5672 C CZ  . TYR E 5 188 ? 112.085 106.718 113.454 1.00 83.34  ? 82  TYR D CZ  1 
ATOM 5673 O OH  . TYR E 5 188 ? 113.032 105.910 112.869 1.00 84.00  ? 82  TYR D OH  1 
ATOM 5674 N N   . ILE E 5 189 ? 106.456 110.561 116.155 1.00 81.36  ? 83  ILE D N   1 
ATOM 5675 C CA  . ILE E 5 189 ? 105.701 111.384 117.095 1.00 81.27  ? 83  ILE D CA  1 
ATOM 5676 C C   . ILE E 5 189 ? 104.461 110.641 117.572 1.00 82.86  ? 83  ILE D C   1 
ATOM 5677 O O   . ILE E 5 189 ? 104.117 110.677 118.760 1.00 86.02  ? 83  ILE D O   1 
ATOM 5678 C CB  . ILE E 5 189 ? 105.346 112.738 116.451 1.00 84.06  ? 83  ILE D CB  1 
ATOM 5679 C CG1 . ILE E 5 189 ? 106.618 113.568 116.255 1.00 84.67  ? 83  ILE D CG1 1 
ATOM 5680 C CG2 . ILE E 5 189 ? 104.329 113.492 117.307 1.00 83.27  ? 83  ILE D CG2 1 
ATOM 5681 C CD1 . ILE E 5 189 ? 106.418 114.852 115.475 1.00 85.24  ? 83  ILE D CD1 1 
ATOM 5682 N N   . LEU E 5 190 ? 103.765 109.964 116.657 1.00 83.33  ? 84  LEU D N   1 
ATOM 5683 C CA  . LEU E 5 190 ? 102.582 109.205 117.042 1.00 85.21  ? 84  LEU D CA  1 
ATOM 5684 C C   . LEU E 5 190 ? 102.940 108.090 118.014 1.00 86.90  ? 84  LEU D C   1 
ATOM 5685 O O   . LEU E 5 190 ? 102.224 107.858 118.995 1.00 86.53  ? 84  LEU D O   1 
ATOM 5686 C CB  . LEU E 5 190 ? 101.905 108.633 115.796 1.00 84.62  ? 84  LEU D CB  1 
ATOM 5687 C CG  . LEU E 5 190 ? 100.567 107.922 116.009 1.00 85.26  ? 84  LEU D CG  1 
ATOM 5688 C CD1 . LEU E 5 190 ? 99.486  108.913 116.411 1.00 84.97  ? 84  LEU D CD1 1 
ATOM 5689 C CD2 . LEU E 5 190 ? 100.165 107.159 114.757 1.00 84.67  ? 84  LEU D CD2 1 
ATOM 5690 N N   . ASN E 5 191 ? 104.045 107.387 117.760 1.00 84.46  ? 85  ASN D N   1 
ATOM 5691 C CA  . ASN E 5 191 ? 104.461 106.316 118.659 1.00 83.75  ? 85  ASN D CA  1 
ATOM 5692 C C   . ASN E 5 191 ? 104.762 106.858 120.053 1.00 83.28  ? 85  ASN D C   1 
ATOM 5693 O O   . ASN E 5 191 ? 104.326 106.291 121.066 1.00 84.48  ? 85  ASN D O   1 
ATOM 5694 C CB  . ASN E 5 191 ? 105.683 105.605 118.079 1.00 82.76  ? 85  ASN D CB  1 
ATOM 5695 C CG  . ASN E 5 191 ? 106.126 104.430 118.917 1.00 83.83  ? 85  ASN D CG  1 
ATOM 5696 O OD1 . ASN E 5 191 ? 105.352 103.890 119.708 1.00 84.41  ? 85  ASN D OD1 1 
ATOM 5697 N ND2 . ASN E 5 191 ? 107.378 104.025 118.751 1.00 83.72  ? 85  ASN D ND2 1 
ATOM 5698 N N   . LEU E 5 192 ? 105.506 107.964 120.122 1.00 76.92  ? 86  LEU D N   1 
ATOM 5699 C CA  . LEU E 5 192 ? 105.843 108.536 121.421 1.00 76.94  ? 86  LEU D CA  1 
ATOM 5700 C C   . LEU E 5 192 ? 104.592 109.003 122.156 1.00 77.95  ? 86  LEU D C   1 
ATOM 5701 O O   . LEU E 5 192 ? 104.457 108.792 123.369 1.00 80.29  ? 86  LEU D O   1 
ATOM 5702 C CB  . LEU E 5 192 ? 106.828 109.690 121.241 1.00 76.09  ? 86  LEU D CB  1 
ATOM 5703 C CG  . LEU E 5 192 ? 107.503 110.221 122.507 1.00 76.08  ? 86  LEU D CG  1 
ATOM 5704 C CD1 . LEU E 5 192 ? 108.404 109.170 123.129 1.00 74.13  ? 86  LEU D CD1 1 
ATOM 5705 C CD2 . LEU E 5 192 ? 108.287 111.479 122.191 1.00 76.94  ? 86  LEU D CD2 1 
ATOM 5706 N N   . ALA E 5 193 ? 103.662 109.638 121.438 1.00 76.33  ? 87  ALA D N   1 
ATOM 5707 C CA  . ALA E 5 193 ? 102.432 110.104 122.069 1.00 75.67  ? 87  ALA D CA  1 
ATOM 5708 C C   . ALA E 5 193 ? 101.596 108.937 122.574 1.00 79.00  ? 87  ALA D C   1 
ATOM 5709 O O   . ALA E 5 193 ? 100.994 109.020 123.648 1.00 81.63  ? 87  ALA D O   1 
ATOM 5710 C CB  . ALA E 5 193 ? 101.629 110.954 121.088 1.00 77.77  ? 87  ALA D CB  1 
ATOM 5711 N N   . LEU E 5 194 ? 101.536 107.846 121.809 1.00 81.72  ? 88  LEU D N   1 
ATOM 5712 C CA  . LEU E 5 194 ? 100.797 106.671 122.258 1.00 82.81  ? 88  LEU D CA  1 
ATOM 5713 C C   . LEU E 5 194 ? 101.411 106.089 123.526 1.00 83.10  ? 88  LEU D C   1 
ATOM 5714 O O   . LEU E 5 194 ? 100.692 105.734 124.471 1.00 82.17  ? 88  LEU D O   1 
ATOM 5715 C CB  . LEU E 5 194 ? 100.768 105.628 121.141 1.00 81.52  ? 88  LEU D CB  1 
ATOM 5716 C CG  . LEU E 5 194 ? 99.813  104.444 121.294 1.00 82.51  ? 88  LEU D CG  1 
ATOM 5717 C CD1 . LEU E 5 194 ? 99.317  103.999 119.928 1.00 82.82  ? 88  LEU D CD1 1 
ATOM 5718 C CD2 . LEU E 5 194 ? 100.483 103.285 122.015 1.00 83.03  ? 88  LEU D CD2 1 
ATOM 5719 N N   . ALA E 5 195 ? 102.743 105.988 123.568 1.00 80.40  ? 89  ALA D N   1 
ATOM 5720 C CA  . ALA E 5 195 ? 103.397 105.479 124.769 1.00 78.01  ? 89  ALA D CA  1 
ATOM 5721 C C   . ALA E 5 195 ? 103.100 106.367 125.972 1.00 78.72  ? 89  ALA D C   1 
ATOM 5722 O O   . ALA E 5 195 ? 102.788 105.870 127.063 1.00 81.85  ? 89  ALA D O   1 
ATOM 5723 C CB  . ALA E 5 195 ? 104.902 105.371 124.541 1.00 78.55  ? 89  ALA D CB  1 
ATOM 5724 N N   . ASP E 5 196 ? 103.182 107.687 125.791 1.00 79.47  ? 90  ASP D N   1 
ATOM 5725 C CA  . ASP E 5 196 ? 102.898 108.598 126.895 1.00 80.62  ? 90  ASP D CA  1 
ATOM 5726 C C   . ASP E 5 196 ? 101.447 108.482 127.348 1.00 81.07  ? 90  ASP D C   1 
ATOM 5727 O O   . ASP E 5 196 ? 101.156 108.534 128.550 1.00 82.89  ? 90  ASP D O   1 
ATOM 5728 C CB  . ASP E 5 196 ? 103.218 110.033 126.481 1.00 80.74  ? 90  ASP D CB  1 
ATOM 5729 C CG  . ASP E 5 196 ? 104.696 110.251 126.232 1.00 82.12  ? 90  ASP D CG  1 
ATOM 5730 O OD1 . ASP E 5 196 ? 105.509 109.456 126.747 1.00 82.89  ? 90  ASP D OD1 1 
ATOM 5731 O OD2 . ASP E 5 196 ? 105.046 111.218 125.523 1.00 80.12  ? 90  ASP D OD2 1 
ATOM 5732 N N   . GLU E 5 197 ? 100.520 108.330 126.401 1.00 84.63  ? 91  GLU D N   1 
ATOM 5733 C CA  . GLU E 5 197 ? 99.115  108.182 126.761 1.00 85.99  ? 91  GLU D CA  1 
ATOM 5734 C C   . GLU E 5 197 ? 98.888  106.921 127.585 1.00 88.60  ? 91  GLU D C   1 
ATOM 5735 O O   . GLU E 5 197 ? 98.148  106.941 128.576 1.00 89.05  ? 91  GLU D O   1 
ATOM 5736 C CB  . GLU E 5 197 ? 98.257  108.157 125.498 1.00 84.96  ? 91  GLU D CB  1 
ATOM 5737 C CG  . GLU E 5 197 ? 96.766  108.054 125.756 1.00 86.48  ? 91  GLU D CG  1 
ATOM 5738 C CD  . GLU E 5 197 ? 95.957  108.053 124.476 1.00 89.40  ? 91  GLU D CD  1 
ATOM 5739 O OE1 . GLU E 5 197 ? 96.560  108.190 123.391 1.00 89.95  ? 91  GLU D OE1 1 
ATOM 5740 O OE2 . GLU E 5 197 ? 94.718  107.912 124.554 1.00 87.58  ? 91  GLU D OE2 1 
ATOM 5741 N N   . LEU E 5 198 ? 99.512  105.810 127.192 1.00 87.71  ? 92  LEU D N   1 
ATOM 5742 C CA  . LEU E 5 198 ? 99.346  104.582 127.965 1.00 87.64  ? 92  LEU D CA  1 
ATOM 5743 C C   . LEU E 5 198 ? 99.977  104.712 129.350 1.00 88.09  ? 92  LEU D C   1 
ATOM 5744 O O   . LEU E 5 198 ? 99.450  104.178 130.333 1.00 87.65  ? 92  LEU D O   1 
ATOM 5745 C CB  . LEU E 5 198 ? 99.935  103.395 127.203 1.00 87.62  ? 92  LEU D CB  1 
ATOM 5746 C CG  . LEU E 5 198 ? 99.306  103.093 125.838 1.00 88.08  ? 92  LEU D CG  1 
ATOM 5747 C CD1 . LEU E 5 198 ? 99.885  101.812 125.259 1.00 87.81  ? 92  LEU D CD1 1 
ATOM 5748 C CD2 . LEU E 5 198 ? 97.789  103.005 125.929 1.00 87.98  ? 92  LEU D CD2 1 
ATOM 5749 N N   . PHE E 5 199 ? 101.099 105.428 129.453 1.00 85.09  ? 93  PHE D N   1 
ATOM 5750 C CA  . PHE E 5 199 ? 101.691 105.676 130.766 1.00 84.03  ? 93  PHE D CA  1 
ATOM 5751 C C   . PHE E 5 199 ? 100.741 106.481 131.650 1.00 84.58  ? 93  PHE D C   1 
ATOM 5752 O O   . PHE E 5 199 ? 100.566 106.180 132.844 1.00 85.22  ? 93  PHE D O   1 
ATOM 5753 C CB  . PHE E 5 199 ? 103.026 106.403 130.583 1.00 84.04  ? 93  PHE D CB  1 
ATOM 5754 C CG  . PHE E 5 199 ? 104.044 106.118 131.653 1.00 83.76  ? 93  PHE D CG  1 
ATOM 5755 C CD1 . PHE E 5 199 ? 104.299 104.824 132.072 1.00 84.08  ? 93  PHE D CD1 1 
ATOM 5756 C CD2 . PHE E 5 199 ? 104.781 107.148 132.208 1.00 84.08  ? 93  PHE D CD2 1 
ATOM 5757 C CE1 . PHE E 5 199 ? 105.240 104.570 133.043 1.00 84.01  ? 93  PHE D CE1 1 
ATOM 5758 C CE2 . PHE E 5 199 ? 105.729 106.897 133.176 1.00 83.05  ? 93  PHE D CE2 1 
ATOM 5759 C CZ  . PHE E 5 199 ? 105.958 105.607 133.592 1.00 83.35  ? 93  PHE D CZ  1 
ATOM 5760 N N   . MET E 5 200 ? 100.105 107.505 131.075 1.00 89.06  ? 94  MET D N   1 
ATOM 5761 C CA  . MET E 5 200 ? 99.105  108.261 131.820 1.00 90.42  ? 94  MET D CA  1 
ATOM 5762 C C   . MET E 5 200 ? 97.959  107.360 132.257 1.00 91.81  ? 94  MET D C   1 
ATOM 5763 O O   . MET E 5 200 ? 97.455  107.483 133.378 1.00 91.47  ? 94  MET D O   1 
ATOM 5764 C CB  . MET E 5 200 ? 98.568  109.413 130.972 1.00 90.23  ? 94  MET D CB  1 
ATOM 5765 C CG  . MET E 5 200 ? 99.575  110.503 130.643 1.00 89.86  ? 94  MET D CG  1 
ATOM 5766 S SD  . MET E 5 200 ? 100.357 111.225 132.090 1.00 92.27  ? 94  MET D SD  1 
ATOM 5767 C CE  . MET E 5 200 ? 101.872 110.277 132.148 1.00 89.78  ? 94  MET D CE  1 
ATOM 5768 N N   . LEU E 5 201 ? 97.525  106.455 131.378 1.00 98.89  ? 95  LEU D N   1 
ATOM 5769 C CA  . LEU E 5 201 ? 96.455  105.530 131.740 1.00 99.48  ? 95  LEU D CA  1 
ATOM 5770 C C   . LEU E 5 201 ? 96.878  104.601 132.869 1.00 97.88  ? 95  LEU D C   1 
ATOM 5771 O O   . LEU E 5 201 ? 96.029  104.139 133.639 1.00 97.11  ? 95  LEU D O   1 
ATOM 5772 C CB  . LEU E 5 201 ? 96.029  104.709 130.523 1.00 100.30 ? 95  LEU D CB  1 
ATOM 5773 C CG  . LEU E 5 201 ? 95.308  105.450 129.394 1.00 100.09 ? 95  LEU D CG  1 
ATOM 5774 C CD1 . LEU E 5 201 ? 95.075  104.511 128.220 1.00 97.90  ? 95  LEU D CD1 1 
ATOM 5775 C CD2 . LEU E 5 201 ? 93.992  106.045 129.873 1.00 98.45  ? 95  LEU D CD2 1 
ATOM 5776 N N   . GLY E 5 202 ? 98.172  104.289 132.960 1.00 96.33  ? 96  GLY D N   1 
ATOM 5777 C CA  . GLY E 5 202 ? 98.661  103.460 134.051 1.00 96.70  ? 96  GLY D CA  1 
ATOM 5778 C C   . GLY E 5 202 ? 98.799  104.176 135.378 1.00 95.99  ? 96  GLY D C   1 
ATOM 5779 O O   . GLY E 5 202 ? 98.723  103.530 136.428 1.00 94.10  ? 96  GLY D O   1 
ATOM 5780 N N   . LEU E 5 203 ? 99.003  105.493 135.354 1.00 98.86  ? 97  LEU D N   1 
ATOM 5781 C CA  . LEU E 5 203 ? 99.219  106.253 136.589 1.00 97.70  ? 97  LEU D CA  1 
ATOM 5782 C C   . LEU E 5 203 ? 98.142  106.055 137.658 1.00 98.13  ? 97  LEU D C   1 
ATOM 5783 O O   . LEU E 5 203 ? 98.498  105.887 138.838 1.00 98.80  ? 97  LEU D O   1 
ATOM 5784 C CB  . LEU E 5 203 ? 99.340  107.740 136.227 1.00 97.83  ? 97  LEU D CB  1 
ATOM 5785 C CG  . LEU E 5 203 ? 100.033 108.689 137.210 1.00 96.75  ? 97  LEU D CG  1 
ATOM 5786 C CD1 . LEU E 5 203 ? 100.391 109.979 136.495 1.00 96.84  ? 97  LEU D CD1 1 
ATOM 5787 C CD2 . LEU E 5 203 ? 99.168  108.988 138.422 1.00 96.58  ? 97  LEU D CD2 1 
ATOM 5788 N N   . PRO E 5 204 ? 96.842  106.086 137.342 1.00 105.71 ? 98  PRO D N   1 
ATOM 5789 C CA  . PRO E 5 204 ? 95.829  106.151 138.412 1.00 106.38 ? 98  PRO D CA  1 
ATOM 5790 C C   . PRO E 5 204 ? 95.852  104.985 139.388 1.00 106.95 ? 98  PRO D C   1 
ATOM 5791 O O   . PRO E 5 204 ? 95.454  105.163 140.545 1.00 105.83 ? 98  PRO D O   1 
ATOM 5792 C CB  . PRO E 5 204 ? 94.506  106.201 137.634 1.00 105.74 ? 98  PRO D CB  1 
ATOM 5793 C CG  . PRO E 5 204 ? 94.865  106.738 136.310 1.00 105.30 ? 98  PRO D CG  1 
ATOM 5794 C CD  . PRO E 5 204 ? 96.226  106.195 136.012 1.00 104.65 ? 98  PRO D CD  1 
ATOM 5795 N N   . PHE E 5 205 ? 96.276  103.793 138.970 1.00 113.38 ? 99  PHE D N   1 
ATOM 5796 C CA  . PHE E 5 205 ? 96.318  102.673 139.907 1.00 113.23 ? 99  PHE D CA  1 
ATOM 5797 C C   . PHE E 5 205 ? 97.336  102.927 141.013 1.00 113.26 ? 99  PHE D C   1 
ATOM 5798 O O   . PHE E 5 205 ? 97.048  102.720 142.199 1.00 113.85 ? 99  PHE D O   1 
ATOM 5799 C CB  . PHE E 5 205 ? 96.630  101.380 139.157 1.00 113.74 ? 99  PHE D CB  1 
ATOM 5800 C CG  . PHE E 5 205 ? 95.613  101.033 138.113 1.00 114.18 ? 99  PHE D CG  1 
ATOM 5801 C CD1 . PHE E 5 205 ? 94.411  100.445 138.467 1.00 115.21 ? 99  PHE D CD1 1 
ATOM 5802 C CD2 . PHE E 5 205 ? 95.854  101.301 136.776 1.00 113.29 ? 99  PHE D CD2 1 
ATOM 5803 C CE1 . PHE E 5 205 ? 93.469  100.126 137.508 1.00 114.57 ? 99  PHE D CE1 1 
ATOM 5804 C CE2 . PHE E 5 205 ? 94.915  100.984 135.812 1.00 113.20 ? 99  PHE D CE2 1 
ATOM 5805 C CZ  . PHE E 5 205 ? 93.722  100.396 136.179 1.00 113.68 ? 99  PHE D CZ  1 
ATOM 5806 N N   . LEU E 5 206 ? 98.533  103.388 140.643 1.00 109.10 ? 100 LEU D N   1 
ATOM 5807 C CA  . LEU E 5 206 ? 99.504  103.807 141.647 1.00 108.42 ? 100 LEU D CA  1 
ATOM 5808 C C   . LEU E 5 206 ? 98.964  104.966 142.472 1.00 108.92 ? 100 LEU D C   1 
ATOM 5809 O O   . LEU E 5 206 ? 99.174  105.024 143.691 1.00 108.71 ? 100 LEU D O   1 
ATOM 5810 C CB  . LEU E 5 206 ? 100.818 104.203 140.976 1.00 108.54 ? 100 LEU D CB  1 
ATOM 5811 C CG  . LEU E 5 206 ? 101.822 103.083 140.698 1.00 107.88 ? 100 LEU D CG  1 
ATOM 5812 C CD1 . LEU E 5 206 ? 101.225 102.005 139.806 1.00 108.22 ? 100 LEU D CD1 1 
ATOM 5813 C CD2 . LEU E 5 206 ? 103.078 103.667 140.075 1.00 108.16 ? 100 LEU D CD2 1 
ATOM 5814 N N   . ALA E 5 207 ? 98.272  105.904 141.819 1.00 114.28 ? 101 ALA D N   1 
ATOM 5815 C CA  . ALA E 5 207 ? 97.684  107.021 142.552 1.00 114.43 ? 101 ALA D CA  1 
ATOM 5816 C C   . ALA E 5 207 ? 96.766  106.524 143.662 1.00 114.14 ? 101 ALA D C   1 
ATOM 5817 O O   . ALA E 5 207 ? 96.822  107.015 144.796 1.00 114.65 ? 101 ALA D O   1 
ATOM 5818 C CB  . ALA E 5 207 ? 96.914  107.927 141.592 1.00 114.55 ? 101 ALA D CB  1 
ATOM 5819 N N   . ALA E 5 208 ? 95.915  105.546 143.350 1.00 117.64 ? 102 ALA D N   1 
ATOM 5820 C CA  . ALA E 5 208 ? 94.978  105.025 144.339 1.00 118.57 ? 102 ALA D CA  1 
ATOM 5821 C C   . ALA E 5 208 ? 95.694  104.218 145.415 1.00 118.28 ? 102 ALA D C   1 
ATOM 5822 O O   . ALA E 5 208 ? 95.352  104.314 146.599 1.00 117.14 ? 102 ALA D O   1 
ATOM 5823 C CB  . ALA E 5 208 ? 93.915  104.169 143.651 1.00 118.52 ? 102 ALA D CB  1 
ATOM 5824 N N   . GLN E 5 209 ? 96.689  103.417 145.024 1.00 122.01 ? 103 GLN D N   1 
ATOM 5825 C CA  . GLN E 5 209 ? 97.341  102.540 145.992 1.00 121.65 ? 103 GLN D CA  1 
ATOM 5826 C C   . GLN E 5 209 ? 98.201  103.319 146.980 1.00 121.87 ? 103 GLN D C   1 
ATOM 5827 O O   . GLN E 5 209 ? 98.302  102.928 148.148 1.00 121.59 ? 103 GLN D O   1 
ATOM 5828 C CB  . GLN E 5 209 ? 98.188  101.494 145.265 1.00 121.16 ? 103 GLN D CB  1 
ATOM 5829 C CG  . GLN E 5 209 ? 98.692  100.356 146.150 1.00 121.56 ? 103 GLN D CG  1 
ATOM 5830 C CD  . GLN E 5 209 ? 99.925  100.725 146.952 1.00 122.16 ? 103 GLN D CD  1 
ATOM 5831 O OE1 . GLN E 5 209 ? 100.572 101.737 146.691 1.00 121.79 ? 103 GLN D OE1 1 
ATOM 5832 N NE2 . GLN E 5 209 ? 100.257 99.898  147.935 1.00 122.27 ? 103 GLN D NE2 1 
ATOM 5833 N N   . ASN E 5 210 ? 98.826  104.412 146.544 1.00 118.79 ? 104 ASN D N   1 
ATOM 5834 C CA  . ASN E 5 210 ? 99.763  105.138 147.394 1.00 118.42 ? 104 ASN D CA  1 
ATOM 5835 C C   . ASN E 5 210 ? 99.081  106.067 148.394 1.00 118.46 ? 104 ASN D C   1 
ATOM 5836 O O   . ASN E 5 210 ? 99.774  106.854 149.048 1.00 117.93 ? 104 ASN D O   1 
ATOM 5837 C CB  . ASN E 5 210 ? 100.734 105.944 146.528 1.00 117.76 ? 104 ASN D CB  1 
ATOM 5838 C CG  . ASN E 5 210 ? 101.722 105.066 145.789 1.00 117.63 ? 104 ASN D CG  1 
ATOM 5839 O OD1 . ASN E 5 210 ? 101.434 103.911 145.480 1.00 117.78 ? 104 ASN D OD1 1 
ATOM 5840 N ND2 . ASN E 5 210 ? 102.899 105.611 145.505 1.00 117.20 ? 104 ASN D ND2 1 
ATOM 5841 N N   . ALA E 5 211 ? 97.759  105.997 148.537 1.00 121.16 ? 105 ALA D N   1 
ATOM 5842 C CA  . ALA E 5 211 ? 97.022  106.882 149.432 1.00 121.33 ? 105 ALA D CA  1 
ATOM 5843 C C   . ALA E 5 211 ? 96.380  106.141 150.592 1.00 121.99 ? 105 ALA D C   1 
ATOM 5844 O O   . ALA E 5 211 ? 96.572  106.527 151.751 1.00 121.72 ? 105 ALA D O   1 
ATOM 5845 C CB  . ALA E 5 211 ? 95.944  107.644 148.644 1.00 120.22 ? 105 ALA D CB  1 
ATOM 5846 N N   . LEU E 5 212 ? 95.621  105.083 150.316 1.00 126.49 ? 106 LEU D N   1 
ATOM 5847 C CA  . LEU E 5 212 ? 94.900  104.349 151.347 1.00 126.48 ? 106 LEU D CA  1 
ATOM 5848 C C   . LEU E 5 212 ? 95.744  103.271 152.014 1.00 126.40 ? 106 LEU D C   1 
ATOM 5849 O O   . LEU E 5 212 ? 95.246  102.591 152.917 1.00 126.33 ? 106 LEU D O   1 
ATOM 5850 C CB  . LEU E 5 212 ? 93.643  103.710 150.748 1.00 126.80 ? 106 LEU D CB  1 
ATOM 5851 C CG  . LEU E 5 212 ? 92.676  104.652 150.027 1.00 126.64 ? 106 LEU D CG  1 
ATOM 5852 C CD1 . LEU E 5 212 ? 91.507  103.871 149.444 1.00 126.16 ? 106 LEU D CD1 1 
ATOM 5853 C CD2 . LEU E 5 212 ? 92.180  105.751 150.955 1.00 126.08 ? 106 LEU D CD2 1 
ATOM 5854 N N   . SER E 5 213 ? 96.999  103.098 151.599 1.00 131.86 ? 107 SER D N   1 
ATOM 5855 C CA  . SER E 5 213 ? 97.850  102.026 152.116 1.00 132.66 ? 107 SER D CA  1 
ATOM 5856 C C   . SER E 5 213 ? 97.180  100.668 151.927 1.00 133.18 ? 107 SER D C   1 
ATOM 5857 O O   . SER E 5 213 ? 97.291  99.775  152.769 1.00 133.02 ? 107 SER D O   1 
ATOM 5858 C CB  . SER E 5 213 ? 98.200  102.258 153.587 1.00 132.50 ? 107 SER D CB  1 
ATOM 5859 O OG  . SER E 5 213 ? 99.093  101.264 154.057 1.00 132.39 ? 107 SER D OG  1 
ATOM 5860 N N   . TYR E 5 214 ? 96.479  100.515 150.808 1.00 137.49 ? 108 TYR D N   1 
ATOM 5861 C CA  . TYR E 5 214 ? 95.722  99.306  150.526 1.00 137.73 ? 108 TYR D CA  1 
ATOM 5862 C C   . TYR E 5 214 ? 95.541  99.199  149.021 1.00 137.52 ? 108 TYR D C   1 
ATOM 5863 O O   . TYR E 5 214 ? 95.535  100.209 148.314 1.00 137.65 ? 108 TYR D O   1 
ATOM 5864 C CB  . TYR E 5 214 ? 94.367  99.322  151.243 1.00 137.62 ? 108 TYR D CB  1 
ATOM 5865 C CG  . TYR E 5 214 ? 93.509  98.109  150.974 1.00 137.69 ? 108 TYR D CG  1 
ATOM 5866 C CD1 . TYR E 5 214 ? 94.001  96.829  151.178 1.00 137.47 ? 108 TYR D CD1 1 
ATOM 5867 C CD2 . TYR E 5 214 ? 92.202  98.244  150.526 1.00 137.18 ? 108 TYR D CD2 1 
ATOM 5868 C CE1 . TYR E 5 214 ? 93.221  95.713  150.935 1.00 137.25 ? 108 TYR D CE1 1 
ATOM 5869 C CE2 . TYR E 5 214 ? 91.414  97.136  150.283 1.00 137.38 ? 108 TYR D CE2 1 
ATOM 5870 C CZ  . TYR E 5 214 ? 91.927  95.874  150.488 1.00 137.63 ? 108 TYR D CZ  1 
ATOM 5871 O OH  . TYR E 5 214 ? 91.141  94.772  150.245 1.00 137.32 ? 108 TYR D OH  1 
ATOM 5872 N N   . TRP E 5 215 ? 95.401  97.963  148.540 1.00 133.96 ? 109 TRP D N   1 
ATOM 5873 C CA  . TRP E 5 215 ? 95.219  97.674  147.121 1.00 134.18 ? 109 TRP D CA  1 
ATOM 5874 C C   . TRP E 5 215 ? 93.835  97.070  146.917 1.00 133.97 ? 109 TRP D C   1 
ATOM 5875 O O   . TRP E 5 215 ? 93.685  95.840  146.908 1.00 133.84 ? 109 TRP D O   1 
ATOM 5876 C CB  . TRP E 5 215 ? 96.309  96.724  146.622 1.00 133.74 ? 109 TRP D CB  1 
ATOM 5877 C CG  . TRP E 5 215 ? 96.136  96.303  145.210 1.00 134.14 ? 109 TRP D CG  1 
ATOM 5878 C CD1 . TRP E 5 215 ? 95.590  95.139  144.765 1.00 133.95 ? 109 TRP D CD1 1 
ATOM 5879 C CD2 . TRP E 5 215 ? 96.515  97.043  144.044 1.00 134.35 ? 109 TRP D CD2 1 
ATOM 5880 N NE1 . TRP E 5 215 ? 95.601  95.109  143.393 1.00 134.42 ? 109 TRP D NE1 1 
ATOM 5881 C CE2 . TRP E 5 215 ? 96.166  96.265  142.926 1.00 133.96 ? 109 TRP D CE2 1 
ATOM 5882 C CE3 . TRP E 5 215 ? 97.113  98.289  143.837 1.00 134.09 ? 109 TRP D CE3 1 
ATOM 5883 C CZ2 . TRP E 5 215 ? 96.392  96.692  141.620 1.00 133.59 ? 109 TRP D CZ2 1 
ATOM 5884 C CZ3 . TRP E 5 215 ? 97.339  98.709  142.541 1.00 134.04 ? 109 TRP D CZ3 1 
ATOM 5885 C CH2 . TRP E 5 215 ? 96.980  97.914  141.450 1.00 133.92 ? 109 TRP D CH2 1 
ATOM 5886 N N   . PRO E 5 216 ? 92.781  97.893  146.748 1.00 134.11 ? 110 PRO D N   1 
ATOM 5887 C CA  . PRO E 5 216 ? 91.411  97.376  146.642 1.00 134.09 ? 110 PRO D CA  1 
ATOM 5888 C C   . PRO E 5 216 ? 91.006  97.009  145.214 1.00 133.75 ? 110 PRO D C   1 
ATOM 5889 O O   . PRO E 5 216 ? 89.915  97.355  144.746 1.00 133.73 ? 110 PRO D O   1 
ATOM 5890 C CB  . PRO E 5 216 ? 90.573  98.536  147.189 1.00 134.35 ? 110 PRO D CB  1 
ATOM 5891 C CG  . PRO E 5 216 ? 91.410  99.772  146.993 1.00 133.98 ? 110 PRO D CG  1 
ATOM 5892 C CD  . PRO E 5 216 ? 92.813  99.361  146.643 1.00 134.09 ? 110 PRO D CD  1 
ATOM 5893 N N   . PHE E 5 217 ? 91.881  96.294  144.511 1.00 130.95 ? 111 PHE D N   1 
ATOM 5894 C CA  . PHE E 5 217 ? 91.620  95.896  143.132 1.00 131.26 ? 111 PHE D CA  1 
ATOM 5895 C C   . PHE E 5 217 ? 91.601  94.388  142.944 1.00 131.39 ? 111 PHE D C   1 
ATOM 5896 O O   . PHE E 5 217 ? 90.666  93.858  142.331 1.00 130.81 ? 111 PHE D O   1 
ATOM 5897 C CB  . PHE E 5 217 ? 92.668  96.527  142.205 1.00 130.51 ? 111 PHE D CB  1 
ATOM 5898 C CG  . PHE E 5 217 ? 92.698  98.027  142.257 1.00 130.68 ? 111 PHE D CG  1 
ATOM 5899 C CD1 . PHE E 5 217 ? 91.752  98.777  141.578 1.00 131.41 ? 111 PHE D CD1 1 
ATOM 5900 C CD2 . PHE E 5 217 ? 93.675  98.690  142.980 1.00 130.43 ? 111 PHE D CD2 1 
ATOM 5901 C CE1 . PHE E 5 217 ? 91.779  100.158 141.623 1.00 130.82 ? 111 PHE D CE1 1 
ATOM 5902 C CE2 . PHE E 5 217 ? 93.708  100.071 143.028 1.00 130.36 ? 111 PHE D CE2 1 
ATOM 5903 C CZ  . PHE E 5 217 ? 92.759  100.804 142.348 1.00 130.55 ? 111 PHE D CZ  1 
ATOM 5904 N N   . GLY E 5 218 ? 92.603  93.676  143.456 1.00 134.45 ? 112 GLY D N   1 
ATOM 5905 C CA  . GLY E 5 218 ? 92.672  92.235  143.292 1.00 133.94 ? 112 GLY D CA  1 
ATOM 5906 C C   . GLY E 5 218 ? 94.063  91.740  142.950 1.00 134.78 ? 112 GLY D C   1 
ATOM 5907 O O   . GLY E 5 218 ? 95.059  92.301  143.418 1.00 134.94 ? 112 GLY D O   1 
ATOM 5908 N N   . SER E 5 219 ? 94.144  90.690  142.134 1.00 130.85 ? 113 SER D N   1 
ATOM 5909 C CA  . SER E 5 219 ? 95.417  90.086  141.752 1.00 130.05 ? 113 SER D CA  1 
ATOM 5910 C C   . SER E 5 219 ? 95.676  90.111  140.255 1.00 129.97 ? 113 SER D C   1 
ATOM 5911 O O   . SER E 5 219 ? 96.796  90.419  139.835 1.00 130.20 ? 113 SER D O   1 
ATOM 5912 C CB  . SER E 5 219 ? 95.475  88.633  142.244 1.00 129.77 ? 113 SER D CB  1 
ATOM 5913 O OG  . SER E 5 219 ? 96.700  88.022  141.880 1.00 129.68 ? 113 SER D OG  1 
ATOM 5914 N N   . LEU E 5 220 ? 94.673  89.798  139.431 1.00 129.97 ? 114 LEU D N   1 
ATOM 5915 C CA  . LEU E 5 220 ? 94.888  89.773  137.987 1.00 129.99 ? 114 LEU D CA  1 
ATOM 5916 C C   . LEU E 5 220 ? 95.279  91.152  137.473 1.00 129.67 ? 114 LEU D C   1 
ATOM 5917 O O   . LEU E 5 220 ? 96.301  91.313  136.792 1.00 129.04 ? 114 LEU D O   1 
ATOM 5918 C CB  . LEU E 5 220 ? 93.631  89.274  137.274 1.00 129.60 ? 114 LEU D CB  1 
ATOM 5919 C CG  . LEU E 5 220 ? 93.276  87.791  137.425 1.00 130.00 ? 114 LEU D CG  1 
ATOM 5920 C CD1 . LEU E 5 220 ? 92.550  87.517  138.737 1.00 129.19 ? 114 LEU D CD1 1 
ATOM 5921 C CD2 . LEU E 5 220 ? 92.442  87.324  136.239 1.00 129.36 ? 114 LEU D CD2 1 
ATOM 5922 N N   . MET E 5 221 ? 94.486  92.171  137.804 1.00 127.39 ? 115 MET D N   1 
ATOM 5923 C CA  . MET E 5 221 ? 94.827  93.512  137.354 1.00 127.44 ? 115 MET D CA  1 
ATOM 5924 C C   . MET E 5 221 ? 96.039  94.066  138.089 1.00 127.20 ? 115 MET D C   1 
ATOM 5925 O O   . MET E 5 221 ? 96.734  94.921  137.537 1.00 127.75 ? 115 MET D O   1 
ATOM 5926 C CB  . MET E 5 221 ? 93.630  94.454  137.499 1.00 127.17 ? 115 MET D CB  1 
ATOM 5927 C CG  . MET E 5 221 ? 93.016  94.538  138.880 1.00 126.78 ? 115 MET D CG  1 
ATOM 5928 S SD  . MET E 5 221 ? 91.561  95.604  138.861 1.00 126.84 ? 115 MET D SD  1 
ATOM 5929 C CE  . MET E 5 221 ? 92.318  97.212  138.625 1.00 126.49 ? 115 MET D CE  1 
ATOM 5930 N N   . CYS E 5 222 ? 96.333  93.586  139.299 1.00 126.85 ? 116 CYS D N   1 
ATOM 5931 C CA  . CYS E 5 222 ? 97.600  93.949  139.927 1.00 127.24 ? 116 CYS D CA  1 
ATOM 5932 C C   . CYS E 5 222 ? 98.775  93.470  139.089 1.00 127.11 ? 116 CYS D C   1 
ATOM 5933 O O   . CYS E 5 222 ? 99.748  94.207  138.889 1.00 127.15 ? 116 CYS D O   1 
ATOM 5934 C CB  . CYS E 5 222 ? 97.694  93.366  141.337 1.00 126.87 ? 116 CYS D CB  1 
ATOM 5935 S SG  . CYS E 5 222 ? 99.391  93.326  141.971 1.00 128.69 ? 116 CYS D SG  1 
ATOM 5936 N N   . ARG E 5 223 ? 98.704  92.235  138.589 1.00 122.50 ? 117 ARG D N   1 
ATOM 5937 C CA  . ARG E 5 223 ? 99.774  91.726  137.740 1.00 122.34 ? 117 ARG D CA  1 
ATOM 5938 C C   . ARG E 5 223 ? 99.803  92.439  136.394 1.00 122.91 ? 117 ARG D C   1 
ATOM 5939 O O   . ARG E 5 223 ? 100.874 92.593  135.798 1.00 123.22 ? 117 ARG D O   1 
ATOM 5940 C CB  . ARG E 5 223 ? 99.609  90.219  137.538 1.00 122.38 ? 117 ARG D CB  1 
ATOM 5941 C CG  . ARG E 5 223 ? 100.872 89.511  137.077 1.00 123.24 ? 117 ARG D CG  1 
ATOM 5942 C CD  . ARG E 5 223 ? 100.663 88.010  136.952 1.00 123.06 ? 117 ARG D CD  1 
ATOM 5943 N NE  . ARG E 5 223 ? 101.913 87.303  136.691 1.00 122.93 ? 117 ARG D NE  1 
ATOM 5944 C CZ  . ARG E 5 223 ? 102.725 86.827  137.626 1.00 122.70 ? 117 ARG D CZ  1 
ATOM 5945 N NH1 . ARG E 5 223 ? 102.455 86.962  138.915 1.00 122.43 ? 117 ARG D NH1 1 
ATOM 5946 N NH2 . ARG E 5 223 ? 103.838 86.198  137.259 1.00 122.64 ? 117 ARG D NH2 1 
ATOM 5947 N N   . LEU E 5 224 ? 98.641  92.870  135.899 1.00 120.04 ? 118 LEU D N   1 
ATOM 5948 C CA  . LEU E 5 224 ? 98.590  93.528  134.594 1.00 119.80 ? 118 LEU D CA  1 
ATOM 5949 C C   . LEU E 5 224 ? 99.118  94.961  134.639 1.00 118.96 ? 118 LEU D C   1 
ATOM 5950 O O   . LEU E 5 224 ? 99.806  95.397  133.706 1.00 118.20 ? 118 LEU D O   1 
ATOM 5951 C CB  . LEU E 5 224 ? 97.158  93.521  134.058 1.00 119.15 ? 118 LEU D CB  1 
ATOM 5952 C CG  . LEU E 5 224 ? 96.581  92.176  133.609 1.00 120.11 ? 118 LEU D CG  1 
ATOM 5953 C CD1 . LEU E 5 224 ? 95.134  92.352  133.174 1.00 119.46 ? 118 LEU D CD1 1 
ATOM 5954 C CD2 . LEU E 5 224 ? 97.407  91.559  132.487 1.00 119.38 ? 118 LEU D CD2 1 
ATOM 5955 N N   . VAL E 5 225 ? 98.782  95.720  135.687 1.00 113.55 ? 119 VAL D N   1 
ATOM 5956 C CA  . VAL E 5 225 ? 99.117  97.142  135.703 1.00 112.90 ? 119 VAL D CA  1 
ATOM 5957 C C   . VAL E 5 225 ? 100.624 97.343  135.766 1.00 113.28 ? 119 VAL D C   1 
ATOM 5958 O O   . VAL E 5 225 ? 101.170 98.218  135.089 1.00 113.85 ? 119 VAL D O   1 
ATOM 5959 C CB  . VAL E 5 225 ? 98.409  97.869  136.863 1.00 112.97 ? 119 VAL D CB  1 
ATOM 5960 C CG1 . VAL E 5 225 ? 96.901  97.905  136.637 1.00 112.78 ? 119 VAL D CG1 1 
ATOM 5961 C CG2 . VAL E 5 225 ? 98.767  97.245  138.210 1.00 113.70 ? 119 VAL D CG2 1 
ATOM 5962 N N   . MET E 5 226 ? 101.322 96.559  136.588 1.00 112.52 ? 120 MET D N   1 
ATOM 5963 C CA  . MET E 5 226 ? 102.773 96.700  136.658 1.00 113.18 ? 120 MET D CA  1 
ATOM 5964 C C   . MET E 5 226 ? 103.412 96.378  135.314 1.00 113.13 ? 120 MET D C   1 
ATOM 5965 O O   . MET E 5 226 ? 104.317 97.090  134.856 1.00 114.13 ? 120 MET D O   1 
ATOM 5966 C CB  . MET E 5 226 ? 103.335 95.797  137.754 1.00 112.42 ? 120 MET D CB  1 
ATOM 5967 C CG  . MET E 5 226 ? 102.677 95.989  139.114 1.00 112.33 ? 120 MET D CG  1 
ATOM 5968 S SD  . MET E 5 226 ? 102.703 97.699  139.682 1.00 114.50 ? 120 MET D SD  1 
ATOM 5969 C CE  . MET E 5 226 ? 104.465 97.980  139.836 1.00 113.40 ? 120 MET D CE  1 
ATOM 5970 N N   . ALA E 5 227 ? 102.940 95.315  134.660 1.00 107.03 ? 121 ALA D N   1 
ATOM 5971 C CA  . ALA E 5 227 ? 103.481 94.943  133.359 1.00 107.88 ? 121 ALA D CA  1 
ATOM 5972 C C   . ALA E 5 227 ? 103.284 96.062  132.345 1.00 108.23 ? 121 ALA D C   1 
ATOM 5973 O O   . ALA E 5 227 ? 104.228 96.464  131.652 1.00 107.70 ? 121 ALA D O   1 
ATOM 5974 C CB  . ALA E 5 227 ? 102.819 93.654  132.872 1.00 108.48 ? 121 ALA D CB  1 
ATOM 5975 N N   . VAL E 5 228 ? 102.060 96.586  132.250 1.00 103.86 ? 122 VAL D N   1 
ATOM 5976 C CA  . VAL E 5 228 ? 101.784 97.605  131.242 1.00 103.20 ? 122 VAL D CA  1 
ATOM 5977 C C   . VAL E 5 228 ? 102.527 98.894  131.571 1.00 102.21 ? 122 VAL D C   1 
ATOM 5978 O O   . VAL E 5 228 ? 102.990 99.602  130.670 1.00 101.37 ? 122 VAL D O   1 
ATOM 5979 C CB  . VAL E 5 228 ? 100.267 97.835  131.101 1.00 102.43 ? 122 VAL D CB  1 
ATOM 5980 C CG1 . VAL E 5 228 ? 99.710  98.572  132.303 1.00 102.19 ? 122 VAL D CG1 1 
ATOM 5981 C CG2 . VAL E 5 228 ? 99.965  98.596  129.819 1.00 102.41 ? 122 VAL D CG2 1 
ATOM 5982 N N   . ASP E 5 229 ? 102.660 99.221  132.858 1.00 98.43  ? 123 ASP D N   1 
ATOM 5983 C CA  . ASP E 5 229 ? 103.384 100.424 133.245 1.00 97.73  ? 123 ASP D CA  1 
ATOM 5984 C C   . ASP E 5 229 ? 104.849 100.329 132.841 1.00 97.54  ? 123 ASP D C   1 
ATOM 5985 O O   . ASP E 5 229 ? 105.404 101.264 132.251 1.00 100.10 ? 123 ASP D O   1 
ATOM 5986 C CB  . ASP E 5 229 ? 103.253 100.644 134.752 1.00 97.56  ? 123 ASP D CB  1 
ATOM 5987 C CG  . ASP E 5 229 ? 103.510 102.079 135.157 1.00 98.31  ? 123 ASP D CG  1 
ATOM 5988 O OD1 . ASP E 5 229 ? 102.668 102.945 134.842 1.00 97.95  ? 123 ASP D OD1 1 
ATOM 5989 O OD2 . ASP E 5 229 ? 104.550 102.341 135.795 1.00 98.10  ? 123 ASP D OD2 1 
ATOM 5990 N N   . GLY E 5 230 ? 105.494 99.202  133.149 1.00 92.19  ? 124 GLY D N   1 
ATOM 5991 C CA  . GLY E 5 230 ? 106.878 99.031  132.738 1.00 93.56  ? 124 GLY D CA  1 
ATOM 5992 C C   . GLY E 5 230 ? 107.036 99.057  131.230 1.00 93.97  ? 124 GLY D C   1 
ATOM 5993 O O   . GLY E 5 230 ? 107.974 99.666  130.698 1.00 94.39  ? 124 GLY D O   1 
ATOM 5994 N N   . ILE E 5 231 ? 106.119 98.396  130.518 1.00 92.86  ? 125 ILE D N   1 
ATOM 5995 C CA  . ILE E 5 231 ? 106.179 98.384  129.061 1.00 93.29  ? 125 ILE D CA  1 
ATOM 5996 C C   . ILE E 5 231 ? 106.097 99.805  128.522 1.00 92.54  ? 125 ILE D C   1 
ATOM 5997 O O   . ILE E 5 231 ? 106.904 100.213 127.683 1.00 91.28  ? 125 ILE D O   1 
ATOM 5998 C CB  . ILE E 5 231 ? 105.064 97.490  128.485 1.00 93.20  ? 125 ILE D CB  1 
ATOM 5999 C CG1 . ILE E 5 231 ? 105.391 96.016  128.744 1.00 93.86  ? 125 ILE D CG1 1 
ATOM 6000 C CG2 . ILE E 5 231 ? 104.878 97.758  126.991 1.00 92.52  ? 125 ILE D CG2 1 
ATOM 6001 C CD1 . ILE E 5 231 ? 104.273 95.046  128.394 1.00 93.70  ? 125 ILE D CD1 1 
ATOM 6002 N N   . ASN E 5 232 ? 105.128 100.586 129.006 1.00 89.09  ? 126 ASN D N   1 
ATOM 6003 C CA  . ASN E 5 232 ? 104.974 101.953 128.522 1.00 86.76  ? 126 ASN D CA  1 
ATOM 6004 C C   . ASN E 5 232 ? 106.204 102.793 128.839 1.00 86.31  ? 126 ASN D C   1 
ATOM 6005 O O   . ASN E 5 232 ? 106.672 103.563 127.992 1.00 88.77  ? 126 ASN D O   1 
ATOM 6006 C CB  . ASN E 5 232 ? 103.725 102.587 129.127 1.00 86.07  ? 126 ASN D CB  1 
ATOM 6007 C CG  . ASN E 5 232 ? 102.453 101.916 128.663 1.00 87.77  ? 126 ASN D CG  1 
ATOM 6008 O OD1 . ASN E 5 232 ? 102.356 101.460 127.523 1.00 87.43  ? 126 ASN D OD1 1 
ATOM 6009 N ND2 . ASN E 5 232 ? 101.465 101.849 129.547 1.00 89.03  ? 126 ASN D ND2 1 
ATOM 6010 N N   . GLN E 5 233 ? 106.742 102.659 130.051 1.00 81.13  ? 127 GLN D N   1 
ATOM 6011 C CA  . GLN E 5 233 ? 107.913 103.441 130.434 1.00 80.65  ? 127 GLN D CA  1 
ATOM 6012 C C   . GLN E 5 233 ? 109.081 103.174 129.494 1.00 82.32  ? 127 GLN D C   1 
ATOM 6013 O O   . GLN E 5 233 ? 109.666 104.105 128.915 1.00 86.87  ? 127 GLN D O   1 
ATOM 6014 C CB  . GLN E 5 233 ? 108.293 103.109 131.878 1.00 80.26  ? 127 GLN D CB  1 
ATOM 6015 C CG  . GLN E 5 233 ? 109.716 103.446 132.269 1.00 80.64  ? 127 GLN D CG  1 
ATOM 6016 C CD  . GLN E 5 233 ? 109.955 103.274 133.754 1.00 82.11  ? 127 GLN D CD  1 
ATOM 6017 O OE1 . GLN E 5 233 ? 109.021 103.045 134.521 1.00 82.32  ? 127 GLN D OE1 1 
ATOM 6018 N NE2 . GLN E 5 233 ? 111.212 103.380 134.169 1.00 81.47  ? 127 GLN D NE2 1 
ATOM 6019 N N   . PHE E 5 234 ? 109.425 101.898 129.311 1.00 82.43  ? 128 PHE D N   1 
ATOM 6020 C CA  . PHE E 5 234 ? 110.598 101.593 128.501 1.00 81.83  ? 128 PHE D CA  1 
ATOM 6021 C C   . PHE E 5 234 ? 110.339 101.844 127.023 1.00 81.88  ? 128 PHE D C   1 
ATOM 6022 O O   . PHE E 5 234 ? 111.264 102.215 126.291 1.00 81.59  ? 128 PHE D O   1 
ATOM 6023 C CB  . PHE E 5 234 ? 111.046 100.159 128.750 1.00 82.82  ? 128 PHE D CB  1 
ATOM 6024 C CG  . PHE E 5 234 ? 111.814 99.992  130.024 1.00 84.61  ? 128 PHE D CG  1 
ATOM 6025 C CD1 . PHE E 5 234 ? 113.106 100.474 130.130 1.00 83.28  ? 128 PHE D CD1 1 
ATOM 6026 C CD2 . PHE E 5 234 ? 111.242 99.373  131.122 1.00 83.55  ? 128 PHE D CD2 1 
ATOM 6027 C CE1 . PHE E 5 234 ? 113.817 100.332 131.301 1.00 83.96  ? 128 PHE D CE1 1 
ATOM 6028 C CE2 . PHE E 5 234 ? 111.952 99.228  132.297 1.00 82.96  ? 128 PHE D CE2 1 
ATOM 6029 C CZ  . PHE E 5 234 ? 113.240 99.710  132.384 1.00 84.30  ? 128 PHE D CZ  1 
ATOM 6030 N N   . THR E 5 235 ? 109.095 101.680 126.565 1.00 84.09  ? 129 THR D N   1 
ATOM 6031 C CA  . THR E 5 235 ? 108.772 102.035 125.190 1.00 82.64  ? 129 THR D CA  1 
ATOM 6032 C C   . THR E 5 235 ? 108.964 103.523 124.955 1.00 83.73  ? 129 THR D C   1 
ATOM 6033 O O   . THR E 5 235 ? 109.515 103.924 123.929 1.00 84.21  ? 129 THR D O   1 
ATOM 6034 C CB  . THR E 5 235 ? 107.337 101.632 124.855 1.00 82.84  ? 129 THR D CB  1 
ATOM 6035 O OG1 . THR E 5 235 ? 106.457 102.085 125.888 1.00 84.77  ? 129 THR D OG1 1 
ATOM 6036 C CG2 . THR E 5 235 ? 107.228 100.135 124.716 1.00 82.82  ? 129 THR D CG2 1 
ATOM 6037 N N   . SER E 5 236 ? 108.528 104.360 125.899 1.00 77.19  ? 130 SER D N   1 
ATOM 6038 C CA  . SER E 5 236 ? 108.732 105.797 125.753 1.00 73.34  ? 130 SER D CA  1 
ATOM 6039 C C   . SER E 5 236 ? 110.215 106.130 125.690 1.00 71.48  ? 130 SER D C   1 
ATOM 6040 O O   . SER E 5 236 ? 110.662 106.890 124.817 1.00 77.55  ? 130 SER D O   1 
ATOM 6041 C CB  . SER E 5 236 ? 108.068 106.537 126.914 1.00 73.58  ? 130 SER D CB  1 
ATOM 6042 O OG  . SER E 5 236 ? 108.511 107.880 126.982 1.00 76.30  ? 130 SER D OG  1 
ATOM 6043 N N   . ILE E 5 237 ? 111.000 105.559 126.605 1.00 63.80  ? 131 ILE D N   1 
ATOM 6044 C CA  . ILE E 5 237 ? 112.425 105.885 126.649 1.00 66.32  ? 131 ILE D CA  1 
ATOM 6045 C C   . ILE E 5 237 ? 113.108 105.468 125.349 1.00 70.78  ? 131 ILE D C   1 
ATOM 6046 O O   . ILE E 5 237 ? 113.814 106.263 124.709 1.00 73.43  ? 131 ILE D O   1 
ATOM 6047 C CB  . ILE E 5 237 ? 113.083 105.230 127.875 1.00 66.61  ? 131 ILE D CB  1 
ATOM 6048 C CG1 . ILE E 5 237 ? 112.669 105.984 129.142 1.00 70.28  ? 131 ILE D CG1 1 
ATOM 6049 C CG2 . ILE E 5 237 ? 114.592 105.205 127.717 1.00 66.46  ? 131 ILE D CG2 1 
ATOM 6050 C CD1 . ILE E 5 237 ? 113.141 105.355 130.438 1.00 71.10  ? 131 ILE D CD1 1 
ATOM 6051 N N   . PHE E 5 238 ? 112.895 104.220 124.926 1.00 76.08  ? 132 PHE D N   1 
ATOM 6052 C CA  . PHE E 5 238 ? 113.544 103.742 123.712 1.00 73.32  ? 132 PHE D CA  1 
ATOM 6053 C C   . PHE E 5 238 ? 113.024 104.460 122.475 1.00 73.62  ? 132 PHE D C   1 
ATOM 6054 O O   . PHE E 5 238 ? 113.783 104.674 121.525 1.00 74.51  ? 132 PHE D O   1 
ATOM 6055 C CB  . PHE E 5 238 ? 113.347 102.232 123.569 1.00 73.64  ? 132 PHE D CB  1 
ATOM 6056 C CG  . PHE E 5 238 ? 114.013 101.423 124.647 1.00 73.73  ? 132 PHE D CG  1 
ATOM 6057 C CD1 . PHE E 5 238 ? 115.236 101.805 125.173 1.00 74.48  ? 132 PHE D CD1 1 
ATOM 6058 C CD2 . PHE E 5 238 ? 113.414 100.273 125.132 1.00 75.95  ? 132 PHE D CD2 1 
ATOM 6059 C CE1 . PHE E 5 238 ? 115.845 101.061 126.161 1.00 76.20  ? 132 PHE D CE1 1 
ATOM 6060 C CE2 . PHE E 5 238 ? 114.020 99.526  126.121 1.00 76.54  ? 132 PHE D CE2 1 
ATOM 6061 C CZ  . PHE E 5 238 ? 115.237 99.921  126.635 1.00 75.99  ? 132 PHE D CZ  1 
ATOM 6062 N N   . CYS E 5 239 ? 111.747 104.842 122.460 1.00 70.50  ? 133 CYS D N   1 
ATOM 6063 C CA  . CYS E 5 239 ? 111.201 105.549 121.312 1.00 71.69  ? 133 CYS D CA  1 
ATOM 6064 C C   . CYS E 5 239 ? 111.839 106.921 121.154 1.00 70.88  ? 133 CYS D C   1 
ATOM 6065 O O   . CYS E 5 239 ? 112.185 107.319 120.038 1.00 72.67  ? 133 CYS D O   1 
ATOM 6066 C CB  . CYS E 5 239 ? 109.685 105.671 121.451 1.00 71.68  ? 133 CYS D CB  1 
ATOM 6067 S SG  . CYS E 5 239 ? 108.884 106.552 120.096 1.00 78.33  ? 133 CYS D SG  1 
ATOM 6068 N N   . LEU E 5 240 ? 112.013 107.663 122.251 1.00 61.49  ? 134 LEU D N   1 
ATOM 6069 C CA  . LEU E 5 240 ? 112.669 108.960 122.099 1.00 59.95  ? 134 LEU D CA  1 
ATOM 6070 C C   . LEU E 5 240 ? 114.157 108.797 121.798 1.00 60.50  ? 134 LEU D C   1 
ATOM 6071 O O   . LEU E 5 240 ? 114.736 109.629 121.088 1.00 66.49  ? 134 LEU D O   1 
ATOM 6072 C CB  . LEU E 5 240 ? 112.434 109.844 123.328 1.00 60.33  ? 134 LEU D CB  1 
ATOM 6073 C CG  . LEU E 5 240 ? 112.787 109.379 124.737 1.00 60.48  ? 134 LEU D CG  1 
ATOM 6074 C CD1 . LEU E 5 240 ? 114.252 109.608 125.039 1.00 59.71  ? 134 LEU D CD1 1 
ATOM 6075 C CD2 . LEU E 5 240 ? 111.911 110.110 125.742 1.00 59.64  ? 134 LEU D CD2 1 
ATOM 6076 N N   . THR E 5 241 ? 114.783 107.715 122.271 1.00 62.78  ? 135 THR D N   1 
ATOM 6077 C CA  . THR E 5 241 ? 116.158 107.434 121.858 1.00 65.29  ? 135 THR D CA  1 
ATOM 6078 C C   . THR E 5 241 ? 116.243 107.195 120.352 1.00 64.53  ? 135 THR D C   1 
ATOM 6079 O O   . THR E 5 241 ? 117.132 107.722 119.669 1.00 63.11  ? 135 THR D O   1 
ATOM 6080 C CB  . THR E 5 241 ? 116.694 106.220 122.615 1.00 64.47  ? 135 THR D CB  1 
ATOM 6081 O OG1 . THR E 5 241 ? 116.568 106.438 124.024 1.00 66.70  ? 135 THR D OG1 1 
ATOM 6082 C CG2 . THR E 5 241 ? 118.154 105.971 122.272 1.00 63.11  ? 135 THR D CG2 1 
ATOM 6083 N N   . VAL E 5 242 ? 115.322 106.393 119.819 1.00 63.90  ? 136 VAL D N   1 
ATOM 6084 C CA  . VAL E 5 242 ? 115.323 106.100 118.391 1.00 60.82  ? 136 VAL D CA  1 
ATOM 6085 C C   . VAL E 5 242 ? 115.013 107.357 117.592 1.00 64.00  ? 136 VAL D C   1 
ATOM 6086 O O   . VAL E 5 242 ? 115.531 107.546 116.488 1.00 68.71  ? 136 VAL D O   1 
ATOM 6087 C CB  . VAL E 5 242 ? 114.333 104.964 118.082 1.00 65.32  ? 136 VAL D CB  1 
ATOM 6088 C CG1 . VAL E 5 242 ? 114.061 104.877 116.591 1.00 64.50  ? 136 VAL D CG1 1 
ATOM 6089 C CG2 . VAL E 5 242 ? 114.874 103.642 118.602 1.00 64.71  ? 136 VAL D CG2 1 
ATOM 6090 N N   . MET E 5 243 ? 114.153 108.226 118.123 1.00 64.79  ? 137 MET D N   1 
ATOM 6091 C CA  . MET E 5 243 ? 113.891 109.501 117.463 1.00 60.91  ? 137 MET D CA  1 
ATOM 6092 C C   . MET E 5 243 ? 115.153 110.349 117.397 1.00 51.94  ? 137 MET D C   1 
ATOM 6093 O O   . MET E 5 243 ? 115.436 110.980 116.371 1.00 57.22  ? 137 MET D O   1 
ATOM 6094 C CB  . MET E 5 243 ? 112.782 110.249 118.198 1.00 60.21  ? 137 MET D CB  1 
ATOM 6095 C CG  . MET E 5 243 ? 112.167 111.385 117.410 1.00 60.12  ? 137 MET D CG  1 
ATOM 6096 S SD  . MET E 5 243 ? 111.009 112.358 118.387 1.00 67.33  ? 137 MET D SD  1 
ATOM 6097 C CE  . MET E 5 243 ? 109.797 111.119 118.829 1.00 61.77  ? 137 MET D CE  1 
ATOM 6098 N N   . SER E 5 244 ? 115.924 110.377 118.484 1.00 44.87  ? 138 SER D N   1 
ATOM 6099 C CA  . SER E 5 244 ? 117.186 111.107 118.468 1.00 47.35  ? 138 SER D CA  1 
ATOM 6100 C C   . SER E 5 244 ? 118.134 110.542 117.415 1.00 55.18  ? 138 SER D C   1 
ATOM 6101 O O   . SER E 5 244 ? 118.765 111.292 116.659 1.00 58.72  ? 138 SER D O   1 
ATOM 6102 C CB  . SER E 5 244 ? 117.833 111.054 119.847 1.00 53.94  ? 138 SER D CB  1 
ATOM 6103 O OG  . SER E 5 244 ? 119.200 111.398 119.764 1.00 59.31  ? 138 SER D OG  1 
ATOM 6104 N N   . VAL E 5 245 ? 118.244 109.214 117.351 1.00 62.69  ? 139 VAL D N   1 
ATOM 6105 C CA  . VAL E 5 245 ? 119.146 108.595 116.379 1.00 60.02  ? 139 VAL D CA  1 
ATOM 6106 C C   . VAL E 5 245 ? 118.673 108.878 114.956 1.00 58.93  ? 139 VAL D C   1 
ATOM 6107 O O   . VAL E 5 245 ? 119.483 109.104 114.049 1.00 57.48  ? 139 VAL D O   1 
ATOM 6108 C CB  . VAL E 5 245 ? 119.269 107.083 116.646 1.00 57.97  ? 139 VAL D CB  1 
ATOM 6109 C CG1 . VAL E 5 245 ? 120.173 106.428 115.612 1.00 58.36  ? 139 VAL D CG1 1 
ATOM 6110 C CG2 . VAL E 5 245 ? 119.808 106.828 118.043 1.00 60.66  ? 139 VAL D CG2 1 
ATOM 6111 N N   . ASP E 5 246 ? 117.358 108.852 114.735 1.00 62.92  ? 140 ASP D N   1 
ATOM 6112 C CA  . ASP E 5 246 ? 116.811 109.130 113.411 1.00 59.77  ? 140 ASP D CA  1 
ATOM 6113 C C   . ASP E 5 246 ? 117.091 110.565 112.986 1.00 61.00  ? 140 ASP D C   1 
ATOM 6114 O O   . ASP E 5 246 ? 117.433 110.817 111.826 1.00 61.87  ? 140 ASP D O   1 
ATOM 6115 C CB  . ASP E 5 246 ? 115.310 108.843 113.405 1.00 62.08  ? 140 ASP D CB  1 
ATOM 6116 C CG  . ASP E 5 246 ? 114.684 109.016 112.036 1.00 67.26  ? 140 ASP D CG  1 
ATOM 6117 O OD1 . ASP E 5 246 ? 115.412 109.341 111.075 1.00 68.29  ? 140 ASP D OD1 1 
ATOM 6118 O OD2 . ASP E 5 246 ? 113.455 108.828 111.919 1.00 66.85  ? 140 ASP D OD2 1 
ATOM 6119 N N   . ARG E 5 247 ? 116.942 111.523 113.902 1.00 60.01  ? 141 ARG D N   1 
ATOM 6120 C CA  . ARG E 5 247 ? 117.300 112.900 113.575 1.00 56.59  ? 141 ARG D CA  1 
ATOM 6121 C C   . ARG E 5 247 ? 118.787 113.015 113.268 1.00 57.24  ? 141 ARG D C   1 
ATOM 6122 O O   . ARG E 5 247 ? 119.190 113.752 112.357 1.00 63.07  ? 141 ARG D O   1 
ATOM 6123 C CB  . ARG E 5 247 ? 116.913 113.834 114.721 1.00 56.81  ? 141 ARG D CB  1 
ATOM 6124 C CG  . ARG E 5 247 ? 115.415 113.995 114.900 1.00 55.22  ? 141 ARG D CG  1 
ATOM 6125 C CD  . ARG E 5 247 ? 115.083 115.026 115.960 1.00 54.49  ? 141 ARG D CD  1 
ATOM 6126 N NE  . ARG E 5 247 ? 113.649 115.278 116.034 1.00 56.80  ? 141 ARG D NE  1 
ATOM 6127 C CZ  . ARG E 5 247 ? 113.083 116.182 116.821 1.00 59.18  ? 141 ARG D CZ  1 
ATOM 6128 N NH1 . ARG E 5 247 ? 113.801 116.945 117.628 1.00 59.92  ? 141 ARG D NH1 1 
ATOM 6129 N NH2 . ARG E 5 247 ? 111.762 116.325 116.796 1.00 57.83  ? 141 ARG D NH2 1 
ATOM 6130 N N   . TYR E 5 248 ? 119.622 112.292 114.018 1.00 56.55  ? 142 TYR D N   1 
ATOM 6131 C CA  . TYR E 5 248 ? 121.053 112.302 113.735 1.00 57.97  ? 142 TYR D CA  1 
ATOM 6132 C C   . TYR E 5 248 ? 121.340 111.789 112.331 1.00 63.84  ? 142 TYR D C   1 
ATOM 6133 O O   . TYR E 5 248 ? 122.143 112.376 111.599 1.00 65.66  ? 142 TYR D O   1 
ATOM 6134 C CB  . TYR E 5 248 ? 121.794 111.461 114.770 1.00 62.02  ? 142 TYR D CB  1 
ATOM 6135 C CG  . TYR E 5 248 ? 123.255 111.254 114.462 1.00 60.57  ? 142 TYR D CG  1 
ATOM 6136 C CD1 . TYR E 5 248 ? 124.190 112.235 114.751 1.00 58.39  ? 142 TYR D CD1 1 
ATOM 6137 C CD2 . TYR E 5 248 ? 123.701 110.072 113.889 1.00 60.65  ? 142 TYR D CD2 1 
ATOM 6138 C CE1 . TYR E 5 248 ? 125.526 112.048 114.475 1.00 58.43  ? 142 TYR D CE1 1 
ATOM 6139 C CE2 . TYR E 5 248 ? 125.034 109.875 113.610 1.00 60.99  ? 142 TYR D CE2 1 
ATOM 6140 C CZ  . TYR E 5 248 ? 125.942 110.865 113.904 1.00 61.99  ? 142 TYR D CZ  1 
ATOM 6141 O OH  . TYR E 5 248 ? 127.274 110.671 113.625 1.00 65.28  ? 142 TYR D OH  1 
ATOM 6142 N N   . LEU E 5 249 ? 120.699 110.688 111.937 1.00 67.10  ? 143 LEU D N   1 
ATOM 6143 C CA  . LEU E 5 249 ? 120.892 110.178 110.582 1.00 63.29  ? 143 LEU D CA  1 
ATOM 6144 C C   . LEU E 5 249 ? 120.397 111.178 109.548 1.00 65.12  ? 143 LEU D C   1 
ATOM 6145 O O   . LEU E 5 249 ? 121.046 111.391 108.518 1.00 68.13  ? 143 LEU D O   1 
ATOM 6146 C CB  . LEU E 5 249 ? 120.174 108.840 110.406 1.00 61.46  ? 143 LEU D CB  1 
ATOM 6147 C CG  . LEU E 5 249 ? 120.673 107.652 111.233 1.00 63.18  ? 143 LEU D CG  1 
ATOM 6148 C CD1 . LEU E 5 249 ? 119.934 106.391 110.820 1.00 63.22  ? 143 LEU D CD1 1 
ATOM 6149 C CD2 . LEU E 5 249 ? 122.177 107.463 111.100 1.00 64.73  ? 143 LEU D CD2 1 
ATOM 6150 N N   . ALA E 5 250 ? 119.249 111.807 109.807 1.00 66.82  ? 144 ALA D N   1 
ATOM 6151 C CA  . ALA E 5 250 ? 118.681 112.747 108.848 1.00 65.32  ? 144 ALA D CA  1 
ATOM 6152 C C   . ALA E 5 250 ? 119.619 113.918 108.598 1.00 62.67  ? 144 ALA D C   1 
ATOM 6153 O O   . ALA E 5 250 ? 119.798 114.345 107.453 1.00 64.46  ? 144 ALA D O   1 
ATOM 6154 C CB  . ALA E 5 250 ? 117.333 113.257 109.352 1.00 68.19  ? 144 ALA D CB  1 
ATOM 6155 N N   . VAL E 5 251 ? 120.224 114.454 109.654 1.00 65.80  ? 145 VAL D N   1 
ATOM 6156 C CA  . VAL E 5 251 ? 121.006 115.680 109.513 1.00 64.95  ? 145 VAL D CA  1 
ATOM 6157 C C   . VAL E 5 251 ? 122.459 115.388 109.152 1.00 68.11  ? 145 VAL D C   1 
ATOM 6158 O O   . VAL E 5 251 ? 123.034 116.061 108.294 1.00 72.43  ? 145 VAL D O   1 
ATOM 6159 C CB  . VAL E 5 251 ? 120.907 116.514 110.806 1.00 67.53  ? 145 VAL D CB  1 
ATOM 6160 C CG1 . VAL E 5 251 ? 121.644 117.838 110.649 1.00 63.78  ? 145 VAL D CG1 1 
ATOM 6161 C CG2 . VAL E 5 251 ? 119.453 116.753 111.172 1.00 66.03  ? 145 VAL D CG2 1 
ATOM 6162 N N   . VAL E 5 252 ? 123.082 114.397 109.784 1.00 61.32  ? 146 VAL D N   1 
ATOM 6163 C CA  . VAL E 5 252 ? 124.522 114.205 109.640 1.00 65.02  ? 146 VAL D CA  1 
ATOM 6164 C C   . VAL E 5 252 ? 124.881 113.206 108.539 1.00 67.42  ? 146 VAL D C   1 
ATOM 6165 O O   . VAL E 5 252 ? 125.959 113.308 107.946 1.00 65.74  ? 146 VAL D O   1 
ATOM 6166 C CB  . VAL E 5 252 ? 125.121 113.770 110.987 1.00 63.88  ? 146 VAL D CB  1 
ATOM 6167 C CG1 . VAL E 5 252 ? 126.642 113.781 110.924 1.00 63.77  ? 146 VAL D CG1 1 
ATOM 6168 C CG2 . VAL E 5 252 ? 124.620 114.675 112.100 1.00 65.40  ? 146 VAL D CG2 1 
ATOM 6169 N N   . HIS E 5 253 ? 124.011 112.239 108.252 1.00 73.43  ? 147 HIS D N   1 
ATOM 6170 C CA  . HIS E 5 253 ? 124.269 111.209 107.244 1.00 69.57  ? 147 HIS D CA  1 
ATOM 6171 C C   . HIS E 5 253 ? 123.083 111.119 106.295 1.00 69.39  ? 147 HIS D C   1 
ATOM 6172 O O   . HIS E 5 253 ? 122.287 110.172 106.368 1.00 67.62  ? 147 HIS D O   1 
ATOM 6173 C CB  . HIS E 5 253 ? 124.536 109.851 107.894 1.00 67.54  ? 147 HIS D CB  1 
ATOM 6174 C CG  . HIS E 5 253 ? 125.870 109.749 108.564 1.00 70.55  ? 147 HIS D CG  1 
ATOM 6175 N ND1 . HIS E 5 253 ? 126.844 110.717 108.442 1.00 71.88  ? 147 HIS D ND1 1 
ATOM 6176 C CD2 . HIS E 5 253 ? 126.393 108.790 109.364 1.00 70.88  ? 147 HIS D CD2 1 
ATOM 6177 C CE1 . HIS E 5 253 ? 127.908 110.359 109.138 1.00 72.37  ? 147 HIS D CE1 1 
ATOM 6178 N NE2 . HIS E 5 253 ? 127.660 109.194 109.708 1.00 71.65  ? 147 HIS D NE2 1 
ATOM 6179 N N   . PRO E 5 254 ? 122.932 112.085 105.385 1.00 76.81  ? 148 PRO D N   1 
ATOM 6180 C CA  . PRO E 5 254 ? 121.882 111.964 104.366 1.00 78.35  ? 148 PRO D CA  1 
ATOM 6181 C C   . PRO E 5 254 ? 122.182 110.840 103.387 1.00 81.01  ? 148 PRO D C   1 
ATOM 6182 O O   . PRO E 5 254 ? 123.185 110.134 103.533 1.00 80.51  ? 148 PRO D O   1 
ATOM 6183 C CB  . PRO E 5 254 ? 121.891 113.336 103.677 1.00 77.04  ? 148 PRO D CB  1 
ATOM 6184 C CG  . PRO E 5 254 ? 122.638 114.240 104.588 1.00 75.11  ? 148 PRO D CG  1 
ATOM 6185 C CD  . PRO E 5 254 ? 123.626 113.378 105.299 1.00 76.36  ? 148 PRO D CD  1 
ATOM 6186 N N   . THR E 5 255 ? 121.329 110.671 102.378 1.00 87.74  ? 149 THR D N   1 
ATOM 6187 C CA  . THR E 5 255 ? 121.500 109.616 101.379 1.00 87.85  ? 149 THR D CA  1 
ATOM 6188 C C   . THR E 5 255 ? 121.459 108.232 102.023 1.00 87.75  ? 149 THR D C   1 
ATOM 6189 O O   . THR E 5 255 ? 122.229 107.337 101.668 1.00 86.30  ? 149 THR D O   1 
ATOM 6190 C CB  . THR E 5 255 ? 122.800 109.802 100.592 1.00 87.13  ? 149 THR D CB  1 
ATOM 6191 O OG1 . THR E 5 255 ? 123.923 109.672 101.473 1.00 87.06  ? 149 THR D OG1 1 
ATOM 6192 C CG2 . THR E 5 255 ? 122.830 111.169 99.923  1.00 85.77  ? 149 THR D CG2 1 
ATOM 6193 N N   . ARG E 5 256 ? 120.558 108.059 102.987 1.00 90.73  ? 150 ARG D N   1 
ATOM 6194 C CA  . ARG E 5 256 ? 120.250 106.765 103.581 1.00 91.15  ? 150 ARG D CA  1 
ATOM 6195 C C   . ARG E 5 256 ? 118.771 106.450 103.404 1.00 91.49  ? 150 ARG D C   1 
ATOM 6196 O O   . ARG E 5 256 ? 118.127 105.872 104.281 1.00 91.97  ? 150 ARG D O   1 
ATOM 6197 C CB  . ARG E 5 256 ? 120.638 106.728 105.058 1.00 90.65  ? 150 ARG D CB  1 
ATOM 6198 C CG  . ARG E 5 256 ? 122.125 106.925 105.323 1.00 89.91  ? 150 ARG D CG  1 
ATOM 6199 C CD  . ARG E 5 256 ? 122.963 105.797 104.742 1.00 90.26  ? 150 ARG D CD  1 
ATOM 6200 N NE  . ARG E 5 256 ? 124.392 106.031 104.914 1.00 90.16  ? 150 ARG D NE  1 
ATOM 6201 C CZ  . ARG E 5 256 ? 125.119 106.833 104.148 1.00 89.43  ? 150 ARG D CZ  1 
ATOM 6202 N NH1 . ARG E 5 256 ? 124.579 107.523 103.157 1.00 89.49  ? 150 ARG D NH1 1 
ATOM 6203 N NH2 . ARG E 5 256 ? 126.422 106.950 104.387 1.00 88.27  ? 150 ARG D NH2 1 
ATOM 6204 N N   . SER E 5 257 ? 118.220 106.828 102.249 1.00 98.36  ? 151 SER D N   1 
ATOM 6205 C CA  . SER E 5 257 ? 116.799 106.648 101.985 1.00 98.75  ? 151 SER D CA  1 
ATOM 6206 C C   . SER E 5 257 ? 116.395 105.183 101.914 1.00 99.94  ? 151 SER D C   1 
ATOM 6207 O O   . SER E 5 257 ? 115.196 104.889 101.939 1.00 99.89  ? 151 SER D O   1 
ATOM 6208 C CB  . SER E 5 257 ? 116.419 107.348 100.681 1.00 98.13  ? 151 SER D CB  1 
ATOM 6209 O OG  . SER E 5 257 ? 116.646 108.744 100.769 1.00 97.98  ? 151 SER D OG  1 
ATOM 6210 N N   . ALA E 5 258 ? 117.358 104.263 101.819 1.00 101.46 ? 152 ALA D N   1 
ATOM 6211 C CA  . ALA E 5 258 ? 117.023 102.845 101.839 1.00 101.07 ? 152 ALA D CA  1 
ATOM 6212 C C   . ALA E 5 258 ? 116.395 102.442 103.165 1.00 100.76 ? 152 ALA D C   1 
ATOM 6213 O O   . ALA E 5 258 ? 115.557 101.534 103.203 1.00 101.18 ? 152 ALA D O   1 
ATOM 6214 C CB  . ALA E 5 258 ? 118.273 102.007 101.571 1.00 99.43  ? 152 ALA D CB  1 
ATOM 6215 N N   . ARG E 5 259 ? 116.784 103.096 104.253 1.00 98.56  ? 153 ARG D N   1 
ATOM 6216 C CA  . ARG E 5 259 ? 116.261 102.779 105.578 1.00 98.77  ? 153 ARG D CA  1 
ATOM 6217 C C   . ARG E 5 259 ? 115.721 103.995 106.316 1.00 99.17  ? 153 ARG D C   1 
ATOM 6218 O O   . ARG E 5 259 ? 114.742 103.867 107.054 1.00 98.88  ? 153 ARG D O   1 
ATOM 6219 C CB  . ARG E 5 259 ? 117.354 102.091 106.428 1.00 98.18  ? 153 ARG D CB  1 
ATOM 6220 C CG  . ARG E 5 259 ? 118.694 102.814 106.483 1.00 97.82  ? 153 ARG D CG  1 
ATOM 6221 C CD  . ARG E 5 259 ? 119.814 101.844 106.832 1.00 98.38  ? 153 ARG D CD  1 
ATOM 6222 N NE  . ARG E 5 259 ? 121.130 102.474 106.805 1.00 98.81  ? 153 ARG D NE  1 
ATOM 6223 C CZ  . ARG E 5 259 ? 121.823 102.846 107.874 1.00 99.35  ? 153 ARG D CZ  1 
ATOM 6224 N NH1 . ARG E 5 259 ? 121.359 102.672 109.102 1.00 99.45  ? 153 ARG D NH1 1 
ATOM 6225 N NH2 . ARG E 5 259 ? 123.019 103.405 107.708 1.00 97.60  ? 153 ARG D NH2 1 
ATOM 6226 N N   . TRP E 5 260 ? 116.329 105.169 106.137 1.00 96.02  ? 154 TRP D N   1 
ATOM 6227 C CA  . TRP E 5 260 ? 115.905 106.334 106.907 1.00 95.90  ? 154 TRP D CA  1 
ATOM 6228 C C   . TRP E 5 260 ? 114.496 106.771 106.529 1.00 97.20  ? 154 TRP D C   1 
ATOM 6229 O O   . TRP E 5 260 ? 113.636 106.946 107.399 1.00 97.47  ? 154 TRP D O   1 
ATOM 6230 C CB  . TRP E 5 260 ? 116.886 107.487 106.704 1.00 96.13  ? 154 TRP D CB  1 
ATOM 6231 C CG  . TRP E 5 260 ? 116.399 108.766 107.303 1.00 97.84  ? 154 TRP D CG  1 
ATOM 6232 C CD1 . TRP E 5 260 ? 116.272 109.052 108.629 1.00 97.50  ? 154 TRP D CD1 1 
ATOM 6233 C CD2 . TRP E 5 260 ? 115.968 109.938 106.597 1.00 97.05  ? 154 TRP D CD2 1 
ATOM 6234 N NE1 . TRP E 5 260 ? 115.788 110.326 108.793 1.00 97.50  ? 154 TRP D NE1 1 
ATOM 6235 C CE2 . TRP E 5 260 ? 115.595 110.892 107.562 1.00 96.75  ? 154 TRP D CE2 1 
ATOM 6236 C CE3 . TRP E 5 260 ? 115.862 110.272 105.243 1.00 95.97  ? 154 TRP D CE3 1 
ATOM 6237 C CZ2 . TRP E 5 260 ? 115.122 112.158 107.217 1.00 95.83  ? 154 TRP D CZ2 1 
ATOM 6238 C CZ3 . TRP E 5 260 ? 115.395 111.527 104.904 1.00 96.09  ? 154 TRP D CZ3 1 
ATOM 6239 C CH2 . TRP E 5 260 ? 115.031 112.455 105.885 1.00 96.53  ? 154 TRP D CH2 1 
ATOM 6240 N N   . ARG E 5 261 ? 114.237 106.952 105.236 1.00 104.44 ? 155 ARG D N   1 
ATOM 6241 C CA  . ARG E 5 261 ? 112.954 107.470 104.782 1.00 104.77 ? 155 ARG D CA  1 
ATOM 6242 C C   . ARG E 5 261 ? 111.966 106.375 104.403 1.00 105.61 ? 155 ARG D C   1 
ATOM 6243 O O   . ARG E 5 261 ? 110.801 106.682 104.129 1.00 106.27 ? 155 ARG D O   1 
ATOM 6244 C CB  . ARG E 5 261 ? 113.163 108.405 103.585 1.00 105.18 ? 155 ARG D CB  1 
ATOM 6245 C CG  . ARG E 5 261 ? 112.006 109.364 103.315 1.00 105.15 ? 155 ARG D CG  1 
ATOM 6246 C CD  . ARG E 5 261 ? 111.850 110.401 104.420 1.00 105.15 ? 155 ARG D CD  1 
ATOM 6247 N NE  . ARG E 5 261 ? 110.690 111.260 104.213 1.00 106.14 ? 155 ARG D NE  1 
ATOM 6248 C CZ  . ARG E 5 261 ? 110.259 112.161 105.085 1.00 106.00 ? 155 ARG D CZ  1 
ATOM 6249 N NH1 . ARG E 5 261 ? 110.871 112.353 106.243 1.00 104.52 ? 155 ARG D NH1 1 
ATOM 6250 N NH2 . ARG E 5 261 ? 109.186 112.888 104.789 1.00 105.26 ? 155 ARG D NH2 1 
ATOM 6251 N N   . THR E 5 262 ? 112.389 105.114 104.390 1.00 103.55 ? 156 THR D N   1 
ATOM 6252 C CA  . THR E 5 262 ? 111.504 104.014 104.024 1.00 103.40 ? 156 THR D CA  1 
ATOM 6253 C C   . THR E 5 262 ? 110.563 103.743 105.192 1.00 103.44 ? 156 THR D C   1 
ATOM 6254 O O   . THR E 5 262 ? 110.987 103.243 106.239 1.00 104.14 ? 156 THR D O   1 
ATOM 6255 C CB  . THR E 5 262 ? 112.321 102.778 103.661 1.00 102.50 ? 156 THR D CB  1 
ATOM 6256 O OG1 . THR E 5 262 ? 113.382 103.149 102.771 1.00 101.95 ? 156 THR D OG1 1 
ATOM 6257 C CG2 . THR E 5 262 ? 111.447 101.734 102.983 1.00 103.28 ? 156 THR D CG2 1 
ATOM 6258 N N   . ALA E 5 263 ? 109.284 104.076 105.014 1.00 103.89 ? 157 ALA D N   1 
ATOM 6259 C CA  . ALA E 5 263 ? 108.329 103.972 106.114 1.00 105.08 ? 157 ALA D CA  1 
ATOM 6260 C C   . ALA E 5 263 ? 108.247 102.570 106.705 1.00 106.27 ? 157 ALA D C   1 
ATOM 6261 O O   . ALA E 5 263 ? 108.153 102.457 107.942 1.00 105.37 ? 157 ALA D O   1 
ATOM 6262 C CB  . ALA E 5 263 ? 106.950 104.448 105.641 1.00 104.56 ? 157 ALA D CB  1 
ATOM 6263 N N   . PRO E 5 264 ? 108.241 101.489 105.919 1.00 107.92 ? 158 PRO D N   1 
ATOM 6264 C CA  . PRO E 5 264 ? 108.280 100.151 106.530 1.00 107.64 ? 158 PRO D CA  1 
ATOM 6265 C C   . PRO E 5 264 ? 109.433 99.964  107.500 1.00 108.18 ? 158 PRO D C   1 
ATOM 6266 O O   . PRO E 5 264 ? 109.263 99.312  108.536 1.00 108.32 ? 158 PRO D O   1 
ATOM 6267 C CB  . PRO E 5 264 ? 108.406 99.224  105.315 1.00 108.42 ? 158 PRO D CB  1 
ATOM 6268 C CG  . PRO E 5 264 ? 107.737 99.954  104.217 1.00 109.14 ? 158 PRO D CG  1 
ATOM 6269 C CD  . PRO E 5 264 ? 107.930 101.425 104.479 1.00 108.47 ? 158 PRO D CD  1 
ATOM 6270 N N   . VAL E 5 265 ? 110.606 100.522 107.195 1.00 103.78 ? 159 VAL D N   1 
ATOM 6271 C CA  . VAL E 5 265 ? 111.743 100.391 108.102 1.00 103.29 ? 159 VAL D CA  1 
ATOM 6272 C C   . VAL E 5 265 ? 111.444 101.079 109.428 1.00 104.32 ? 159 VAL D C   1 
ATOM 6273 O O   . VAL E 5 265 ? 111.721 100.535 110.504 1.00 104.58 ? 159 VAL D O   1 
ATOM 6274 C CB  . VAL E 5 265 ? 113.015 100.952 107.441 1.00 103.70 ? 159 VAL D CB  1 
ATOM 6275 C CG1 . VAL E 5 265 ? 114.201 100.869 108.393 1.00 103.98 ? 159 VAL D CG1 1 
ATOM 6276 C CG2 . VAL E 5 265 ? 113.305 100.198 106.151 1.00 104.43 ? 159 VAL D CG2 1 
ATOM 6277 N N   . ALA E 5 266 ? 110.872 102.284 109.375 1.00 103.95 ? 160 ALA D N   1 
ATOM 6278 C CA  . ALA E 5 266 ? 110.533 102.993 110.604 1.00 103.38 ? 160 ALA D CA  1 
ATOM 6279 C C   . ALA E 5 266 ? 109.499 102.223 111.417 1.00 104.58 ? 160 ALA D C   1 
ATOM 6280 O O   . ALA E 5 266 ? 109.610 102.122 112.647 1.00 104.97 ? 160 ALA D O   1 
ATOM 6281 C CB  . ALA E 5 266 ? 110.019 104.393 110.274 1.00 101.34 ? 160 ALA D CB  1 
ATOM 6282 N N   . ARG E 5 267 ? 108.481 101.676 110.750 1.00 104.13 ? 161 ARG D N   1 
ATOM 6283 C CA  . ARG E 5 267 ? 107.454 100.935 111.475 1.00 105.04 ? 161 ARG D CA  1 
ATOM 6284 C C   . ARG E 5 267 ? 108.029 99.672  112.104 1.00 103.75 ? 161 ARG D C   1 
ATOM 6285 O O   . ARG E 5 267 ? 107.682 99.320  113.240 1.00 101.79 ? 161 ARG D O   1 
ATOM 6286 C CB  . ARG E 5 267 ? 106.294 100.596 110.539 1.00 104.60 ? 161 ARG D CB  1 
ATOM 6287 C CG  . ARG E 5 267 ? 105.033 100.124 111.253 1.00 104.32 ? 161 ARG D CG  1 
ATOM 6288 C CD  . ARG E 5 267 ? 104.372 101.248 112.046 1.00 104.67 ? 161 ARG D CD  1 
ATOM 6289 N NE  . ARG E 5 267 ? 103.355 100.751 112.965 1.00 105.06 ? 161 ARG D NE  1 
ATOM 6290 C CZ  . ARG E 5 267 ? 102.882 101.430 114.001 1.00 104.10 ? 161 ARG D CZ  1 
ATOM 6291 N NH1 . ARG E 5 267 ? 103.320 102.645 114.293 1.00 103.93 ? 161 ARG D NH1 1 
ATOM 6292 N NH2 . ARG E 5 267 ? 101.950 100.874 114.769 1.00 102.44 ? 161 ARG D NH2 1 
ATOM 6293 N N   . THR E 5 268 ? 108.911 98.975  111.383 1.00 103.23 ? 162 THR D N   1 
ATOM 6294 C CA  . THR E 5 268 ? 109.558 97.799  111.950 1.00 103.63 ? 162 THR D CA  1 
ATOM 6295 C C   . THR E 5 268 ? 110.434 98.174  113.136 1.00 103.55 ? 162 THR D C   1 
ATOM 6296 O O   . THR E 5 268 ? 110.507 97.428  114.116 1.00 102.85 ? 162 THR D O   1 
ATOM 6297 C CB  . THR E 5 268 ? 110.384 97.085  110.882 1.00 102.01 ? 162 THR D CB  1 
ATOM 6298 O OG1 . THR E 5 268 ? 111.225 98.031  110.210 1.00 102.43 ? 162 THR D OG1 1 
ATOM 6299 C CG2 . THR E 5 268 ? 109.475 96.400  109.875 1.00 101.96 ? 162 THR D CG2 1 
ATOM 6300 N N   . VAL E 5 269 ? 111.110 99.323  113.068 1.00 100.70 ? 163 VAL D N   1 
ATOM 6301 C CA  . VAL E 5 269 ? 111.910 99.774  114.203 1.00 100.06 ? 163 VAL D CA  1 
ATOM 6302 C C   . VAL E 5 269 ? 111.016 100.039 115.408 1.00 98.87  ? 163 VAL D C   1 
ATOM 6303 O O   . VAL E 5 269 ? 111.362 99.699  116.546 1.00 100.24 ? 163 VAL D O   1 
ATOM 6304 C CB  . VAL E 5 269 ? 112.726 101.022 113.821 1.00 99.67  ? 163 VAL D CB  1 
ATOM 6305 C CG1 . VAL E 5 269 ? 113.293 101.684 115.062 1.00 98.59  ? 163 VAL D CG1 1 
ATOM 6306 C CG2 . VAL E 5 269 ? 113.844 100.653 112.858 1.00 100.58 ? 163 VAL D CG2 1 
ATOM 6307 N N   . SER E 5 270 ? 109.862 100.669 115.180 1.00 96.43  ? 164 SER D N   1 
ATOM 6308 C CA  . SER E 5 270 ? 108.930 100.922 116.275 1.00 98.54  ? 164 SER D CA  1 
ATOM 6309 C C   . SER E 5 270 ? 108.464 99.613  116.907 1.00 99.61  ? 164 SER D C   1 
ATOM 6310 O O   . SER E 5 270 ? 108.453 99.464  118.138 1.00 98.33  ? 164 SER D O   1 
ATOM 6311 C CB  . SER E 5 270 ? 107.736 101.726 115.762 1.00 98.02  ? 164 SER D CB  1 
ATOM 6312 O OG  . SER E 5 270 ? 107.071 101.033 114.722 1.00 98.16  ? 164 SER D OG  1 
ATOM 6313 N N   . ALA E 5 271 ? 108.080 98.646  116.073 1.00 99.82  ? 165 ALA D N   1 
ATOM 6314 C CA  . ALA E 5 271 ? 107.655 97.352  116.597 1.00 97.28  ? 165 ALA D CA  1 
ATOM 6315 C C   . ALA E 5 271 ? 108.788 96.674  117.358 1.00 97.56  ? 165 ALA D C   1 
ATOM 6316 O O   . ALA E 5 271 ? 108.564 96.062  118.409 1.00 98.35  ? 165 ALA D O   1 
ATOM 6317 C CB  . ALA E 5 271 ? 107.164 96.461  115.459 1.00 96.42  ? 165 ALA D CB  1 
ATOM 6318 N N   . ALA E 5 272 ? 110.013 96.770  116.838 1.00 93.72  ? 166 ALA D N   1 
ATOM 6319 C CA  . ALA E 5 272 ? 111.155 96.148  117.494 1.00 93.07  ? 166 ALA D CA  1 
ATOM 6320 C C   . ALA E 5 272 ? 111.409 96.760  118.863 1.00 93.84  ? 166 ALA D C   1 
ATOM 6321 O O   . ALA E 5 272 ? 111.714 96.043  119.821 1.00 92.66  ? 166 ALA D O   1 
ATOM 6322 C CB  . ALA E 5 272 ? 112.396 96.281  116.614 1.00 91.53  ? 166 ALA D CB  1 
ATOM 6323 N N   . VAL E 5 273 ? 111.309 98.086  118.977 1.00 94.27  ? 167 VAL D N   1 
ATOM 6324 C CA  . VAL E 5 273 ? 111.545 98.713  120.275 1.00 93.67  ? 167 VAL D CA  1 
ATOM 6325 C C   . VAL E 5 273 ? 110.428 98.356  121.246 1.00 94.10  ? 167 VAL D C   1 
ATOM 6326 O O   . VAL E 5 273 ? 110.673 98.166  122.442 1.00 94.30  ? 167 VAL D O   1 
ATOM 6327 C CB  . VAL E 5 273 ? 111.720 100.237 120.143 1.00 92.36  ? 167 VAL D CB  1 
ATOM 6328 C CG1 . VAL E 5 273 ? 112.963 100.556 119.335 1.00 91.52  ? 167 VAL D CG1 1 
ATOM 6329 C CG2 . VAL E 5 273 ? 110.501 100.883 119.530 1.00 91.97  ? 167 VAL D CG2 1 
ATOM 6330 N N   . TRP E 5 274 ? 109.187 98.259  120.762 1.00 94.27  ? 168 TRP D N   1 
ATOM 6331 C CA  . TRP E 5 274 ? 108.112 97.815  121.648 1.00 94.57  ? 168 TRP D CA  1 
ATOM 6332 C C   . TRP E 5 274 ? 108.361 96.393  122.144 1.00 95.28  ? 168 TRP D C   1 
ATOM 6333 O O   . TRP E 5 274 ? 108.165 96.093  123.330 1.00 94.04  ? 168 TRP D O   1 
ATOM 6334 C CB  . TRP E 5 274 ? 106.761 97.914  120.938 1.00 93.72  ? 168 TRP D CB  1 
ATOM 6335 C CG  . TRP E 5 274 ? 106.145 99.280  121.017 1.00 94.00  ? 168 TRP D CG  1 
ATOM 6336 C CD1 . TRP E 5 274 ? 106.475 100.371 120.271 1.00 93.33  ? 168 TRP D CD1 1 
ATOM 6337 C CD2 . TRP E 5 274 ? 105.089 99.700  121.893 1.00 94.70  ? 168 TRP D CD2 1 
ATOM 6338 N NE1 . TRP E 5 274 ? 105.693 101.443 120.625 1.00 93.90  ? 168 TRP D NE1 1 
ATOM 6339 C CE2 . TRP E 5 274 ? 104.835 101.057 121.619 1.00 93.75  ? 168 TRP D CE2 1 
ATOM 6340 C CE3 . TRP E 5 274 ? 104.334 99.061  122.881 1.00 94.86  ? 168 TRP D CE3 1 
ATOM 6341 C CZ2 . TRP E 5 274 ? 103.860 101.786 122.296 1.00 92.73  ? 168 TRP D CZ2 1 
ATOM 6342 C CZ3 . TRP E 5 274 ? 103.368 99.788  123.552 1.00 94.37  ? 168 TRP D CZ3 1 
ATOM 6343 C CH2 . TRP E 5 274 ? 103.140 101.134 123.257 1.00 93.02  ? 168 TRP D CH2 1 
ATOM 6344 N N   . VAL E 5 275 ? 108.803 95.504  121.253 1.00 97.57  ? 169 VAL D N   1 
ATOM 6345 C CA  . VAL E 5 275 ? 109.071 94.123  121.649 1.00 98.06  ? 169 VAL D CA  1 
ATOM 6346 C C   . VAL E 5 275 ? 110.226 94.066  122.642 1.00 98.41  ? 169 VAL D C   1 
ATOM 6347 O O   . VAL E 5 275 ? 110.175 93.332  123.636 1.00 99.05  ? 169 VAL D O   1 
ATOM 6348 C CB  . VAL E 5 275 ? 109.345 93.258  120.405 1.00 97.98  ? 169 VAL D CB  1 
ATOM 6349 C CG1 . VAL E 5 275 ? 109.901 91.896  120.805 1.00 97.62  ? 169 VAL D CG1 1 
ATOM 6350 C CG2 . VAL E 5 275 ? 108.071 93.101  119.585 1.00 96.92  ? 169 VAL D CG2 1 
ATOM 6351 N N   . ALA E 5 276 ? 111.292 94.825  122.383 1.00 96.89  ? 170 ALA D N   1 
ATOM 6352 C CA  . ALA E 5 276 ? 112.414 94.863  123.316 1.00 96.40  ? 170 ALA D CA  1 
ATOM 6353 C C   . ALA E 5 276 ? 111.983 95.405  124.674 1.00 97.09  ? 170 ALA D C   1 
ATOM 6354 O O   . ALA E 5 276 ? 112.421 94.902  125.716 1.00 97.76  ? 170 ALA D O   1 
ATOM 6355 C CB  . ALA E 5 276 ? 113.553 95.698  122.732 1.00 95.79  ? 170 ALA D CB  1 
ATOM 6356 N N   . SER E 5 277 ? 111.127 96.428  124.691 1.00 97.36  ? 171 SER D N   1 
ATOM 6357 C CA  . SER E 5 277 ? 110.596 96.912  125.960 1.00 98.00  ? 171 SER D CA  1 
ATOM 6358 C C   . SER E 5 277 ? 109.859 95.799  126.690 1.00 98.01  ? 171 SER D C   1 
ATOM 6359 O O   . SER E 5 277 ? 110.075 95.574  127.886 1.00 97.42  ? 171 SER D O   1 
ATOM 6360 C CB  . SER E 5 277 ? 109.658 98.088  125.721 1.00 98.17  ? 171 SER D CB  1 
ATOM 6361 O OG  . SER E 5 277 ? 108.638 97.709  124.818 1.00 99.05  ? 171 SER D OG  1 
ATOM 6362 N N   . ALA E 5 278 ? 108.980 95.087  125.980 1.00 102.80 ? 172 ALA D N   1 
ATOM 6363 C CA  . ALA E 5 278 ? 108.247 94.000  126.620 1.00 103.88 ? 172 ALA D CA  1 
ATOM 6364 C C   . ALA E 5 278 ? 109.193 92.930  127.152 1.00 102.67 ? 172 ALA D C   1 
ATOM 6365 O O   . ALA E 5 278 ? 108.907 92.302  128.178 1.00 102.04 ? 172 ALA D O   1 
ATOM 6366 C CB  . ALA E 5 278 ? 107.241 93.380  125.649 1.00 103.59 ? 172 ALA D CB  1 
ATOM 6367 N N   . VAL E 5 279 ? 110.317 92.704  126.468 1.00 102.20 ? 173 VAL D N   1 
ATOM 6368 C CA  . VAL E 5 279 ? 111.284 91.713  126.937 1.00 102.08 ? 173 VAL D CA  1 
ATOM 6369 C C   . VAL E 5 279 ? 111.977 92.197  128.206 1.00 102.25 ? 173 VAL D C   1 
ATOM 6370 O O   . VAL E 5 279 ? 112.231 91.412  129.127 1.00 102.21 ? 173 VAL D O   1 
ATOM 6371 C CB  . VAL E 5 279 ? 112.301 91.391  125.828 1.00 100.91 ? 173 VAL D CB  1 
ATOM 6372 C CG1 . VAL E 5 279 ? 113.479 90.592  126.386 1.00 100.26 ? 173 VAL D CG1 1 
ATOM 6373 C CG2 . VAL E 5 279 ? 111.626 90.633  124.699 1.00 100.30 ? 173 VAL D CG2 1 
ATOM 6374 N N   . VAL E 5 280 ? 112.305 93.489  128.271 1.00 103.25 ? 174 VAL D N   1 
ATOM 6375 C CA  . VAL E 5 280 ? 113.029 94.015  129.428 1.00 103.75 ? 174 VAL D CA  1 
ATOM 6376 C C   . VAL E 5 280 ? 112.198 93.862  130.696 1.00 103.50 ? 174 VAL D C   1 
ATOM 6377 O O   . VAL E 5 280 ? 112.723 93.530  131.766 1.00 103.24 ? 174 VAL D O   1 
ATOM 6378 C CB  . VAL E 5 280 ? 113.422 95.484  129.185 1.00 103.48 ? 174 VAL D CB  1 
ATOM 6379 C CG1 . VAL E 5 280 ? 113.907 96.134  130.476 1.00 102.84 ? 174 VAL D CG1 1 
ATOM 6380 C CG2 . VAL E 5 280 ? 114.488 95.574  128.104 1.00 102.89 ? 174 VAL D CG2 1 
ATOM 6381 N N   . VAL E 5 281 ? 110.888 94.110  130.599 1.00 105.71 ? 175 VAL D N   1 
ATOM 6382 C CA  . VAL E 5 281 ? 110.003 94.063  131.763 1.00 106.71 ? 175 VAL D CA  1 
ATOM 6383 C C   . VAL E 5 281 ? 109.668 92.645  132.193 1.00 108.12 ? 175 VAL D C   1 
ATOM 6384 O O   . VAL E 5 281 ? 108.963 92.462  133.194 1.00 109.09 ? 175 VAL D O   1 
ATOM 6385 C CB  . VAL E 5 281 ? 108.708 94.843  131.450 1.00 107.52 ? 175 VAL D CB  1 
ATOM 6386 C CG1 . VAL E 5 281 ? 107.792 94.899  132.663 1.00 107.38 ? 175 VAL D CG1 1 
ATOM 6387 C CG2 . VAL E 5 281 ? 109.032 96.252  130.968 1.00 107.47 ? 175 VAL D CG2 1 
ATOM 6388 N N   . LEU E 5 282 ? 110.170 91.633  131.487 1.00 110.47 ? 176 LEU D N   1 
ATOM 6389 C CA  . LEU E 5 282 ? 109.735 90.264  131.749 1.00 110.17 ? 176 LEU D CA  1 
ATOM 6390 C C   . LEU E 5 282 ? 109.930 89.833  133.198 1.00 111.08 ? 176 LEU D C   1 
ATOM 6391 O O   . LEU E 5 282 ? 109.022 89.178  133.740 1.00 111.90 ? 176 LEU D O   1 
ATOM 6392 C CB  . LEU E 5 282 ? 110.461 89.311  130.789 1.00 109.77 ? 176 LEU D CB  1 
ATOM 6393 C CG  . LEU E 5 282 ? 109.870 87.912  130.603 1.00 110.60 ? 176 LEU D CG  1 
ATOM 6394 C CD1 . LEU E 5 282 ? 108.432 87.972  130.104 1.00 110.84 ? 176 LEU D CD1 1 
ATOM 6395 C CD2 . LEU E 5 282 ? 110.736 87.113  129.642 1.00 109.91 ? 176 LEU D CD2 1 
ATOM 6396 N N   . PRO E 5 283 ? 111.049 90.129  133.870 1.00 112.63 ? 177 PRO D N   1 
ATOM 6397 C CA  . PRO E 5 283 ? 111.141 89.769  135.296 1.00 112.58 ? 177 PRO D CA  1 
ATOM 6398 C C   . PRO E 5 283 ? 110.027 90.370  136.133 1.00 111.54 ? 177 PRO D C   1 
ATOM 6399 O O   . PRO E 5 283 ? 109.522 89.715  137.054 1.00 112.15 ? 177 PRO D O   1 
ATOM 6400 C CB  . PRO E 5 283 ? 112.518 90.311  135.704 1.00 111.91 ? 177 PRO D CB  1 
ATOM 6401 C CG  . PRO E 5 283 ? 113.294 90.366  134.446 1.00 112.14 ? 177 PRO D CG  1 
ATOM 6402 C CD  . PRO E 5 283 ? 112.306 90.715  133.374 1.00 111.88 ? 177 PRO D CD  1 
ATOM 6403 N N   . VAL E 5 284 ? 109.621 91.604  135.830 1.00 114.04 ? 178 VAL D N   1 
ATOM 6404 C CA  . VAL E 5 284 ? 108.532 92.232  136.572 1.00 115.29 ? 178 VAL D CA  1 
ATOM 6405 C C   . VAL E 5 284 ? 107.249 91.431  136.400 1.00 115.55 ? 178 VAL D C   1 
ATOM 6406 O O   . VAL E 5 284 ? 106.503 91.207  137.362 1.00 115.63 ? 178 VAL D O   1 
ATOM 6407 C CB  . VAL E 5 284 ? 108.352 93.693  136.119 1.00 115.14 ? 178 VAL D CB  1 
ATOM 6408 C CG1 . VAL E 5 284 ? 107.225 94.366  136.891 1.00 114.53 ? 178 VAL D CG1 1 
ATOM 6409 C CG2 . VAL E 5 284 ? 109.653 94.471  136.281 1.00 114.45 ? 178 VAL D CG2 1 
ATOM 6410 N N   . VAL E 5 285 ? 106.969 90.989  135.173 1.00 115.86 ? 179 VAL D N   1 
ATOM 6411 C CA  . VAL E 5 285 ? 105.761 90.212  134.921 1.00 115.81 ? 179 VAL D CA  1 
ATOM 6412 C C   . VAL E 5 285 ? 105.833 88.864  135.629 1.00 116.50 ? 179 VAL D C   1 
ATOM 6413 O O   . VAL E 5 285 ? 104.854 88.413  136.236 1.00 116.66 ? 179 VAL D O   1 
ATOM 6414 C CB  . VAL E 5 285 ? 105.547 90.039  133.406 1.00 115.59 ? 179 VAL D CB  1 
ATOM 6415 C CG1 . VAL E 5 285 ? 104.241 89.306  133.129 1.00 115.77 ? 179 VAL D CG1 1 
ATOM 6416 C CG2 . VAL E 5 285 ? 105.571 91.389  132.701 1.00 115.47 ? 179 VAL D CG2 1 
ATOM 6417 N N   . VAL E 5 286 ? 106.987 88.199  135.560 1.00 118.36 ? 180 VAL D N   1 
ATOM 6418 C CA  . VAL E 5 286 ? 107.091 86.838  136.080 1.00 117.98 ? 180 VAL D CA  1 
ATOM 6419 C C   . VAL E 5 286 ? 107.027 86.830  137.603 1.00 117.79 ? 180 VAL D C   1 
ATOM 6420 O O   . VAL E 5 286 ? 106.324 86.008  138.201 1.00 117.77 ? 180 VAL D O   1 
ATOM 6421 C CB  . VAL E 5 286 ? 108.378 86.169  135.564 1.00 116.96 ? 180 VAL D CB  1 
ATOM 6422 C CG1 . VAL E 5 286 ? 108.574 84.807  136.217 1.00 116.97 ? 180 VAL D CG1 1 
ATOM 6423 C CG2 . VAL E 5 286 ? 108.335 86.028  134.049 1.00 117.08 ? 180 VAL D CG2 1 
ATOM 6424 N N   . PHE E 5 287 ? 107.751 87.738  138.255 1.00 122.09 ? 181 PHE D N   1 
ATOM 6425 C CA  . PHE E 5 287 ? 107.865 87.725  139.708 1.00 121.95 ? 181 PHE D CA  1 
ATOM 6426 C C   . PHE E 5 287 ? 106.801 88.563  140.406 1.00 122.27 ? 181 PHE D C   1 
ATOM 6427 O O   . PHE E 5 287 ? 106.855 88.703  141.632 1.00 122.61 ? 181 PHE D O   1 
ATOM 6428 C CB  . PHE E 5 287 ? 109.256 88.214  140.131 1.00 122.44 ? 181 PHE D CB  1 
ATOM 6429 C CG  . PHE E 5 287 ? 110.389 87.351  139.637 1.00 122.15 ? 181 PHE D CG  1 
ATOM 6430 C CD1 . PHE E 5 287 ? 110.184 86.021  139.303 1.00 121.75 ? 181 PHE D CD1 1 
ATOM 6431 C CD2 . PHE E 5 287 ? 111.666 87.873  139.512 1.00 122.85 ? 181 PHE D CD2 1 
ATOM 6432 C CE1 . PHE E 5 287 ? 111.225 85.234  138.852 1.00 122.00 ? 181 PHE D CE1 1 
ATOM 6433 C CE2 . PHE E 5 287 ? 112.711 87.088  139.062 1.00 122.63 ? 181 PHE D CE2 1 
ATOM 6434 C CZ  . PHE E 5 287 ? 112.489 85.768  138.732 1.00 122.10 ? 181 PHE D CZ  1 
ATOM 6435 N N   . SER E 5 288 ? 105.841 89.120  139.673 1.00 124.23 ? 182 SER D N   1 
ATOM 6436 C CA  . SER E 5 288 ? 104.759 89.856  140.310 1.00 125.05 ? 182 SER D CA  1 
ATOM 6437 C C   . SER E 5 288 ? 103.862 88.905  141.095 1.00 125.45 ? 182 SER D C   1 
ATOM 6438 O O   . SER E 5 288 ? 103.646 87.755  140.706 1.00 124.45 ? 182 SER D O   1 
ATOM 6439 C CB  . SER E 5 288 ? 103.936 90.609  139.265 1.00 124.40 ? 182 SER D CB  1 
ATOM 6440 O OG  . SER E 5 288 ? 102.809 91.231  139.856 1.00 123.82 ? 182 SER D OG  1 
ATOM 6441 N N   . GLY E 5 289 ? 103.340 89.396  142.214 1.00 131.51 ? 183 GLY D N   1 
ATOM 6442 C CA  . GLY E 5 289 ? 102.486 88.573  143.052 1.00 131.28 ? 183 GLY D CA  1 
ATOM 6443 C C   . GLY E 5 289 ? 101.798 89.407  144.108 1.00 132.17 ? 183 GLY D C   1 
ATOM 6444 O O   . GLY E 5 289 ? 102.072 90.599  144.270 1.00 132.04 ? 183 GLY D O   1 
ATOM 6445 N N   . VAL E 5 290 ? 100.889 88.753  144.824 1.00 137.14 ? 184 VAL D N   1 
ATOM 6446 C CA  . VAL E 5 290 ? 100.119 89.389  145.890 1.00 136.86 ? 184 VAL D CA  1 
ATOM 6447 C C   . VAL E 5 290 ? 100.188 88.506  147.131 1.00 136.79 ? 184 VAL D C   1 
ATOM 6448 O O   . VAL E 5 290 ? 99.216  87.801  147.439 1.00 136.57 ? 184 VAL D O   1 
ATOM 6449 C CB  . VAL E 5 290 ? 98.664  89.629  145.458 1.00 136.35 ? 184 VAL D CB  1 
ATOM 6450 C CG1 . VAL E 5 290 ? 97.934  90.486  146.484 1.00 136.12 ? 184 VAL D CG1 1 
ATOM 6451 C CG2 . VAL E 5 290 ? 98.617  90.276  144.081 1.00 136.01 ? 184 VAL D CG2 1 
ATOM 6452 N N   . PRO E 5 291 ? 101.302 88.504  147.868 1.00 138.07 ? 185 PRO D N   1 
ATOM 6453 C CA  . PRO E 5 291 ? 101.397 87.615  149.038 1.00 137.94 ? 185 PRO D CA  1 
ATOM 6454 C C   . PRO E 5 291 ? 100.323 87.863  150.084 1.00 138.16 ? 185 PRO D C   1 
ATOM 6455 O O   . PRO E 5 291 ? 99.852  86.905  150.711 1.00 137.81 ? 185 PRO D O   1 
ATOM 6456 C CB  . PRO E 5 291 ? 102.801 87.911  149.589 1.00 137.58 ? 185 PRO D CB  1 
ATOM 6457 C CG  . PRO E 5 291 ? 103.156 89.250  149.046 1.00 137.96 ? 185 PRO D CG  1 
ATOM 6458 C CD  . PRO E 5 291 ? 102.515 89.318  147.697 1.00 137.73 ? 185 PRO D CD  1 
ATOM 6459 N N   . ARG E 5 292 ? 99.918  89.114  150.290 1.00 141.89 ? 186 ARG D N   1 
ATOM 6460 C CA  . ARG E 5 292 ? 98.886  89.459  151.256 1.00 141.68 ? 186 ARG D CA  1 
ATOM 6461 C C   . ARG E 5 292 ? 97.852  90.356  150.591 1.00 142.01 ? 186 ARG D C   1 
ATOM 6462 O O   . ARG E 5 292 ? 98.144  91.046  149.610 1.00 142.21 ? 186 ARG D O   1 
ATOM 6463 C CB  . ARG E 5 292 ? 99.473  90.169  152.486 1.00 141.93 ? 186 ARG D CB  1 
ATOM 6464 C CG  . ARG E 5 292 ? 100.329 89.282  153.386 1.00 142.40 ? 186 ARG D CG  1 
ATOM 6465 C CD  . ARG E 5 292 ? 99.496  88.358  154.270 1.00 142.64 ? 186 ARG D CD  1 
ATOM 6466 N NE  . ARG E 5 292 ? 98.593  89.092  155.153 1.00 142.93 ? 186 ARG D NE  1 
ATOM 6467 C CZ  . ARG E 5 292 ? 97.291  89.251  154.953 1.00 142.80 ? 186 ARG D CZ  1 
ATOM 6468 N NH1 . ARG E 5 292 ? 96.677  88.730  153.903 1.00 143.10 ? 186 ARG D NH1 1 
ATOM 6469 N NH2 . ARG E 5 292 ? 96.582  89.952  155.834 1.00 142.06 ? 186 ARG D NH2 1 
ATOM 6470 N N   . GLY E 5 293 ? 96.634  90.330  151.132 1.00 140.31 ? 187 GLY D N   1 
ATOM 6471 C CA  . GLY E 5 293 ? 95.581  91.175  150.593 1.00 140.19 ? 187 GLY D CA  1 
ATOM 6472 C C   . GLY E 5 293 ? 95.904  92.652  150.711 1.00 140.88 ? 187 GLY D C   1 
ATOM 6473 O O   . GLY E 5 293 ? 95.685  93.426  149.776 1.00 140.51 ? 187 GLY D O   1 
ATOM 6474 N N   . MET E 5 294 ? 96.426  93.064  151.863 1.00 141.93 ? 188 MET D N   1 
ATOM 6475 C CA  . MET E 5 294 ? 96.700  94.476  152.120 1.00 141.82 ? 188 MET D CA  1 
ATOM 6476 C C   . MET E 5 294 ? 97.878  94.918  151.264 1.00 141.64 ? 188 MET D C   1 
ATOM 6477 O O   . MET E 5 294 ? 99.034  94.607  151.562 1.00 141.22 ? 188 MET D O   1 
ATOM 6478 C CB  . MET E 5 294 ? 96.978  94.706  153.601 1.00 141.57 ? 188 MET D CB  1 
ATOM 6479 C CG  . MET E 5 294 ? 95.842  94.279  154.518 1.00 141.42 ? 188 MET D CG  1 
ATOM 6480 S SD  . MET E 5 294 ? 94.297  95.147  154.188 1.00 142.15 ? 188 MET D SD  1 
ATOM 6481 C CE  . MET E 5 294 ? 93.214  94.357  155.376 1.00 140.62 ? 188 MET D CE  1 
ATOM 6482 N N   . SER E 5 295 ? 97.583  95.662  150.199 1.00 137.56 ? 189 SER D N   1 
ATOM 6483 C CA  . SER E 5 295 ? 98.589  96.211  149.286 1.00 137.35 ? 189 SER D CA  1 
ATOM 6484 C C   . SER E 5 295 ? 99.405  95.050  148.730 1.00 137.54 ? 189 SER D C   1 
ATOM 6485 O O   . SER E 5 295 ? 98.806  94.123  148.158 1.00 137.72 ? 189 SER D O   1 
ATOM 6486 C CB  . SER E 5 295 ? 99.379  97.287  150.032 1.00 137.24 ? 189 SER D CB  1 
ATOM 6487 O OG  . SER E 5 295 ? 98.543  98.378  150.373 1.00 136.35 ? 189 SER D OG  1 
ATOM 6488 N N   . THR E 5 296 ? 100.728 95.036  148.877 1.00 135.74 ? 190 THR D N   1 
ATOM 6489 C CA  . THR E 5 296 ? 101.560 93.925  148.419 1.00 135.66 ? 190 THR D CA  1 
ATOM 6490 C C   . THR E 5 296 ? 101.328 93.615  146.942 1.00 135.71 ? 190 THR D C   1 
ATOM 6491 O O   . THR E 5 296 ? 101.388 92.460  146.515 1.00 135.98 ? 190 THR D O   1 
ATOM 6492 C CB  . THR E 5 296 ? 101.319 92.673  149.263 1.00 136.18 ? 190 THR D CB  1 
ATOM 6493 O OG1 . THR E 5 296 ? 99.929  92.325  149.221 1.00 136.59 ? 190 THR D OG1 1 
ATOM 6494 C CG2 . THR E 5 296 ? 101.753 92.895  150.708 1.00 135.85 ? 190 THR D CG2 1 
ATOM 6495 N N   . CYS E 5 297 ? 101.067 94.651  146.148 1.00 132.72 ? 191 CYS D N   1 
ATOM 6496 C CA  . CYS E 5 297 ? 101.029 94.495  144.694 1.00 132.97 ? 191 CYS D CA  1 
ATOM 6497 C C   . CYS E 5 297 ? 102.432 94.712  144.126 1.00 132.96 ? 191 CYS D C   1 
ATOM 6498 O O   . CYS E 5 297 ? 102.686 95.587  143.298 1.00 133.31 ? 191 CYS D O   1 
ATOM 6499 C CB  . CYS E 5 297 ? 100.015 95.448  144.071 1.00 132.98 ? 191 CYS D CB  1 
ATOM 6500 S SG  . CYS E 5 297 ? 99.885  95.276  142.271 1.00 134.18 ? 191 CYS D SG  1 
ATOM 6501 N N   . HIS E 5 298 ? 103.352 93.874  144.602 1.00 132.33 ? 192 HIS D N   1 
ATOM 6502 C CA  . HIS E 5 298 ? 104.767 94.004  144.284 1.00 132.39 ? 192 HIS D CA  1 
ATOM 6503 C C   . HIS E 5 298 ? 105.309 92.703  143.707 1.00 132.43 ? 192 HIS D C   1 
ATOM 6504 O O   . HIS E 5 298 ? 104.539 91.806  143.348 1.00 132.79 ? 192 HIS D O   1 
ATOM 6505 C CB  . HIS E 5 298 ? 105.558 94.409  145.531 1.00 132.28 ? 192 HIS D CB  1 
ATOM 6506 C CG  . HIS E 5 298 ? 105.497 93.404  146.639 1.00 132.97 ? 192 HIS D CG  1 
ATOM 6507 N ND1 . HIS E 5 298 ? 104.844 93.649  147.828 1.00 133.23 ? 192 HIS D ND1 1 
ATOM 6508 C CD2 . HIS E 5 298 ? 106.013 92.157  146.744 1.00 132.47 ? 192 HIS D CD2 1 
ATOM 6509 C CE1 . HIS E 5 298 ? 104.957 92.594  148.615 1.00 133.08 ? 192 HIS D CE1 1 
ATOM 6510 N NE2 . HIS E 5 298 ? 105.661 91.674  147.981 1.00 132.47 ? 192 HIS D NE2 1 
ATOM 6511 N N   . MET E 5 299 ? 106.630 92.597  143.610 1.00 130.74 ? 193 MET D N   1 
ATOM 6512 C CA  . MET E 5 299 ? 107.279 91.436  143.017 1.00 130.98 ? 193 MET D CA  1 
ATOM 6513 C C   . MET E 5 299 ? 107.497 90.370  144.085 1.00 131.51 ? 193 MET D C   1 
ATOM 6514 O O   . MET E 5 299 ? 108.178 90.617  145.087 1.00 131.62 ? 193 MET D O   1 
ATOM 6515 C CB  . MET E 5 299 ? 108.606 91.841  142.380 1.00 130.65 ? 193 MET D CB  1 
ATOM 6516 C CG  . MET E 5 299 ? 108.483 92.995  141.393 1.00 131.15 ? 193 MET D CG  1 
ATOM 6517 S SD  . MET E 5 299 ? 110.057 93.489  140.673 1.00 132.44 ? 193 MET D SD  1 
ATOM 6518 C CE  . MET E 5 299 ? 110.546 91.965  139.872 1.00 130.54 ? 193 MET D CE  1 
ATOM 6519 N N   . GLN E 5 300 ? 106.923 89.186  143.866 1.00 130.91 ? 194 GLN D N   1 
ATOM 6520 C CA  . GLN E 5 300 ? 107.105 88.064  144.778 1.00 130.49 ? 194 GLN D CA  1 
ATOM 6521 C C   . GLN E 5 300 ? 108.510 87.502  144.615 1.00 130.82 ? 194 GLN D C   1 
ATOM 6522 O O   . GLN E 5 300 ? 108.734 86.594  143.807 1.00 130.49 ? 194 GLN D O   1 
ATOM 6523 C CB  . GLN E 5 300 ? 106.055 86.983  144.514 1.00 130.28 ? 194 GLN D CB  1 
ATOM 6524 C CG  . GLN E 5 300 ? 106.085 85.815  145.491 1.00 130.36 ? 194 GLN D CG  1 
ATOM 6525 C CD  . GLN E 5 300 ? 105.564 86.187  146.863 1.00 130.54 ? 194 GLN D CD  1 
ATOM 6526 O OE1 . GLN E 5 300 ? 104.849 87.175  147.022 1.00 130.86 ? 194 GLN D OE1 1 
ATOM 6527 N NE2 . GLN E 5 300 ? 105.920 85.393  147.866 1.00 130.16 ? 194 GLN D NE2 1 
ATOM 6528 N N   . TRP E 5 301 ? 109.460 88.033  145.379 1.00 127.98 ? 195 TRP D N   1 
ATOM 6529 C CA  . TRP E 5 301 ? 110.856 87.706  145.158 1.00 127.25 ? 195 TRP D CA  1 
ATOM 6530 C C   . TRP E 5 301 ? 111.171 86.286  145.634 1.00 127.65 ? 195 TRP D C   1 
ATOM 6531 O O   . TRP E 5 301 ? 110.533 85.778  146.560 1.00 127.59 ? 195 TRP D O   1 
ATOM 6532 C CB  . TRP E 5 301 ? 111.752 88.706  145.880 1.00 127.10 ? 195 TRP D CB  1 
ATOM 6533 C CG  . TRP E 5 301 ? 111.790 90.049  145.224 1.00 128.15 ? 195 TRP D CG  1 
ATOM 6534 C CD1 . TRP E 5 301 ? 111.303 91.222  145.722 1.00 127.87 ? 195 TRP D CD1 1 
ATOM 6535 C CD2 . TRP E 5 301 ? 112.345 90.358  143.941 1.00 127.99 ? 195 TRP D CD2 1 
ATOM 6536 N NE1 . TRP E 5 301 ? 111.525 92.242  144.827 1.00 127.40 ? 195 TRP D NE1 1 
ATOM 6537 C CE2 . TRP E 5 301 ? 112.164 91.736  143.726 1.00 127.41 ? 195 TRP D CE2 1 
ATOM 6538 C CE3 . TRP E 5 301 ? 112.978 89.601  142.953 1.00 127.72 ? 195 TRP D CE3 1 
ATOM 6539 C CZ2 . TRP E 5 301 ? 112.595 92.372  142.565 1.00 126.52 ? 195 TRP D CZ2 1 
ATOM 6540 C CZ3 . TRP E 5 301 ? 113.406 90.234  141.804 1.00 127.45 ? 195 TRP D CZ3 1 
ATOM 6541 C CH2 . TRP E 5 301 ? 113.216 91.605  141.619 1.00 126.61 ? 195 TRP D CH2 1 
ATOM 6542 N N   . PRO E 5 302 ? 112.160 85.618  145.012 1.00 130.02 ? 196 PRO D N   1 
ATOM 6543 C CA  . PRO E 5 302 ? 112.567 84.290  145.495 1.00 129.98 ? 196 PRO D CA  1 
ATOM 6544 C C   . PRO E 5 302 ? 113.348 84.354  146.799 1.00 129.69 ? 196 PRO D C   1 
ATOM 6545 O O   . PRO E 5 302 ? 113.452 85.418  147.419 1.00 129.40 ? 196 PRO D O   1 
ATOM 6546 C CB  . PRO E 5 302 ? 113.435 83.743  144.352 1.00 129.33 ? 196 PRO D CB  1 
ATOM 6547 C CG  . PRO E 5 302 ? 113.143 84.608  143.176 1.00 128.85 ? 196 PRO D CG  1 
ATOM 6548 C CD  . PRO E 5 302 ? 112.815 85.947  143.734 1.00 129.24 ? 196 PRO D CD  1 
ATOM 6549 N N   . GLU E 5 303 ? 113.895 83.214  147.224 1.00 130.52 ? 197 GLU D N   1 
ATOM 6550 C CA  . GLU E 5 303 ? 114.597 83.160  148.505 1.00 130.70 ? 197 GLU D CA  1 
ATOM 6551 C C   . GLU E 5 303 ? 115.778 84.119  148.565 1.00 130.60 ? 197 GLU D C   1 
ATOM 6552 O O   . GLU E 5 303 ? 115.884 84.870  149.551 1.00 129.99 ? 197 GLU D O   1 
ATOM 6553 C CB  . GLU E 5 303 ? 115.033 81.719  148.795 1.00 130.33 ? 197 GLU D CB  1 
ATOM 6554 C CG  . GLU E 5 303 ? 113.889 80.711  148.813 1.00 129.48 ? 197 GLU D CG  1 
ATOM 6555 C CD  . GLU E 5 303 ? 113.586 80.122  147.446 1.00 129.75 ? 197 GLU D CD  1 
ATOM 6556 O OE1 . GLU E 5 303 ? 114.219 80.543  146.454 1.00 130.29 ? 197 GLU D OE1 1 
ATOM 6557 O OE2 . GLU E 5 303 ? 112.709 79.236  147.362 1.00 129.62 ? 197 GLU D OE2 1 
ATOM 6558 N N   . PRO E 5 304 ? 116.691 84.159  147.581 1.00 130.19 ? 198 PRO D N   1 
ATOM 6559 C CA  . PRO E 5 304 ? 117.727 85.202  147.599 1.00 129.76 ? 198 PRO D CA  1 
ATOM 6560 C C   . PRO E 5 304 ? 117.148 86.560  147.231 1.00 129.94 ? 198 PRO D C   1 
ATOM 6561 O O   . PRO E 5 304 ? 117.457 87.125  146.177 1.00 129.84 ? 198 PRO D O   1 
ATOM 6562 C CB  . PRO E 5 304 ? 118.752 84.706  146.570 1.00 129.72 ? 198 PRO D CB  1 
ATOM 6563 C CG  . PRO E 5 304 ? 118.004 83.789  145.684 1.00 129.86 ? 198 PRO D CG  1 
ATOM 6564 C CD  . PRO E 5 304 ? 116.910 83.179  146.504 1.00 130.03 ? 198 PRO D CD  1 
ATOM 6565 N N   . ALA E 5 305 ? 116.290 87.086  148.109 1.00 129.77 ? 199 ALA D N   1 
ATOM 6566 C CA  . ALA E 5 305 ? 115.555 88.307  147.796 1.00 129.89 ? 199 ALA D CA  1 
ATOM 6567 C C   . ALA E 5 305 ? 116.484 89.508  147.664 1.00 129.37 ? 199 ALA D C   1 
ATOM 6568 O O   . ALA E 5 305 ? 116.301 90.340  146.771 1.00 128.21 ? 199 ALA D O   1 
ATOM 6569 C CB  . ALA E 5 305 ? 114.496 88.568  148.866 1.00 128.87 ? 199 ALA D CB  1 
ATOM 6570 N N   . ALA E 5 306 ? 117.469 89.632  148.555 1.00 127.11 ? 200 ALA D N   1 
ATOM 6571 C CA  . ALA E 5 306 ? 118.351 90.796  148.523 1.00 127.09 ? 200 ALA D CA  1 
ATOM 6572 C C   . ALA E 5 306 ? 119.119 90.872  147.208 1.00 126.92 ? 200 ALA D C   1 
ATOM 6573 O O   . ALA E 5 306 ? 119.136 91.916  146.543 1.00 126.30 ? 200 ALA D O   1 
ATOM 6574 C CB  . ALA E 5 306 ? 119.314 90.753  149.709 1.00 126.61 ? 200 ALA D CB  1 
ATOM 6575 N N   . ALA E 5 307 ? 119.780 89.775  146.828 1.00 125.60 ? 201 ALA D N   1 
ATOM 6576 C CA  . ALA E 5 307 ? 120.552 89.771  145.591 1.00 125.37 ? 201 ALA D CA  1 
ATOM 6577 C C   . ALA E 5 307 ? 119.654 89.981  144.381 1.00 125.29 ? 201 ALA D C   1 
ATOM 6578 O O   . ALA E 5 307 ? 120.014 90.712  143.453 1.00 124.96 ? 201 ALA D O   1 
ATOM 6579 C CB  . ALA E 5 307 ? 121.330 88.463  145.460 1.00 125.09 ? 201 ALA D CB  1 
ATOM 6580 N N   . TRP E 5 308 ? 118.486 89.336  144.364 1.00 126.73 ? 202 TRP D N   1 
ATOM 6581 C CA  . TRP E 5 308 ? 117.552 89.528  143.259 1.00 126.70 ? 202 TRP D CA  1 
ATOM 6582 C C   . TRP E 5 308 ? 117.148 90.992  143.131 1.00 126.87 ? 202 TRP D C   1 
ATOM 6583 O O   . TRP E 5 308 ? 117.136 91.553  142.029 1.00 127.09 ? 202 TRP D O   1 
ATOM 6584 C CB  . TRP E 5 308 ? 116.315 88.656  143.463 1.00 126.52 ? 202 TRP D CB  1 
ATOM 6585 C CG  . TRP E 5 308 ? 116.378 87.328  142.792 1.00 127.27 ? 202 TRP D CG  1 
ATOM 6586 C CD1 . TRP E 5 308 ? 116.475 86.113  143.394 1.00 127.15 ? 202 TRP D CD1 1 
ATOM 6587 C CD2 . TRP E 5 308 ? 116.337 87.075  141.382 1.00 127.18 ? 202 TRP D CD2 1 
ATOM 6588 N NE1 . TRP E 5 308 ? 116.503 85.116  142.449 1.00 126.76 ? 202 TRP D NE1 1 
ATOM 6589 C CE2 . TRP E 5 308 ? 116.419 85.682  141.205 1.00 127.46 ? 202 TRP D CE2 1 
ATOM 6590 C CE3 . TRP E 5 308 ? 116.242 87.893  140.252 1.00 126.29 ? 202 TRP D CE3 1 
ATOM 6591 C CZ2 . TRP E 5 308 ? 116.409 85.086  139.946 1.00 126.95 ? 202 TRP D CZ2 1 
ATOM 6592 C CZ3 . TRP E 5 308 ? 116.233 87.300  139.004 1.00 126.26 ? 202 TRP D CZ3 1 
ATOM 6593 C CH2 . TRP E 5 308 ? 116.315 85.912  138.860 1.00 126.50 ? 202 TRP D CH2 1 
ATOM 6594 N N   . ARG E 5 309 ? 116.792 91.620  144.253 1.00 122.63 ? 203 ARG D N   1 
ATOM 6595 C CA  . ARG E 5 309 ? 116.373 93.016  144.231 1.00 122.72 ? 203 ARG D CA  1 
ATOM 6596 C C   . ARG E 5 309 ? 117.496 93.921  143.745 1.00 121.62 ? 203 ARG D C   1 
ATOM 6597 O O   . ARG E 5 309 ? 117.276 94.810  142.908 1.00 120.04 ? 203 ARG D O   1 
ATOM 6598 C CB  . ARG E 5 309 ? 115.913 93.424  145.630 1.00 121.85 ? 203 ARG D CB  1 
ATOM 6599 C CG  . ARG E 5 309 ? 115.550 94.890  145.787 1.00 121.41 ? 203 ARG D CG  1 
ATOM 6600 C CD  . ARG E 5 309 ? 114.924 95.167  147.149 1.00 121.89 ? 203 ARG D CD  1 
ATOM 6601 N NE  . ARG E 5 309 ? 113.798 94.285  147.429 1.00 122.55 ? 203 ARG D NE  1 
ATOM 6602 C CZ  . ARG E 5 309 ? 113.078 94.320  148.542 1.00 122.29 ? 203 ARG D CZ  1 
ATOM 6603 N NH1 . ARG E 5 309 ? 113.302 95.222  149.484 1.00 121.26 ? 203 ARG D NH1 1 
ATOM 6604 N NH2 . ARG E 5 309 ? 112.108 93.427  148.715 1.00 121.85 ? 203 ARG D NH2 1 
ATOM 6605 N N   . ALA E 5 310 ? 118.710 93.708  144.258 1.00 118.51 ? 204 ALA D N   1 
ATOM 6606 C CA  . ALA E 5 310 ? 119.842 94.519  143.828 1.00 117.53 ? 204 ALA D CA  1 
ATOM 6607 C C   . ALA E 5 310 ? 120.096 94.346  142.337 1.00 117.01 ? 204 ALA D C   1 
ATOM 6608 O O   . ALA E 5 310 ? 120.320 95.324  141.616 1.00 117.14 ? 204 ALA D O   1 
ATOM 6609 C CB  . ALA E 5 310 ? 121.087 94.150  144.634 1.00 117.52 ? 204 ALA D CB  1 
ATOM 6610 N N   . GLY E 5 311 ? 120.061 93.103  141.856 1.00 114.14 ? 205 GLY D N   1 
ATOM 6611 C CA  . GLY E 5 311 ? 120.274 92.868  140.439 1.00 114.32 ? 205 GLY D CA  1 
ATOM 6612 C C   . GLY E 5 311 ? 119.226 93.548  139.584 1.00 114.31 ? 205 GLY D C   1 
ATOM 6613 O O   . GLY E 5 311 ? 119.546 94.194  138.585 1.00 113.77 ? 205 GLY D O   1 
ATOM 6614 N N   . PHE E 5 312 ? 117.955 93.417  139.971 1.00 111.92 ? 206 PHE D N   1 
ATOM 6615 C CA  . PHE E 5 312 ? 116.885 94.072  139.228 1.00 111.44 ? 206 PHE D CA  1 
ATOM 6616 C C   . PHE E 5 312 ? 117.125 95.571  139.141 1.00 112.29 ? 206 PHE D C   1 
ATOM 6617 O O   . PHE E 5 312 ? 117.085 96.159  138.052 1.00 112.08 ? 206 PHE D O   1 
ATOM 6618 C CB  . PHE E 5 312 ? 115.537 93.785  139.891 1.00 111.76 ? 206 PHE D CB  1 
ATOM 6619 C CG  . PHE E 5 312 ? 114.428 94.695  139.437 1.00 112.83 ? 206 PHE D CG  1 
ATOM 6620 C CD1 . PHE E 5 312 ? 114.188 95.898  140.084 1.00 112.42 ? 206 PHE D CD1 1 
ATOM 6621 C CD2 . PHE E 5 312 ? 113.618 94.344  138.371 1.00 112.48 ? 206 PHE D CD2 1 
ATOM 6622 C CE1 . PHE E 5 312 ? 113.172 96.734  139.670 1.00 111.22 ? 206 PHE D CE1 1 
ATOM 6623 C CE2 . PHE E 5 312 ? 112.597 95.177  137.955 1.00 111.70 ? 206 PHE D CE2 1 
ATOM 6624 C CZ  . PHE E 5 312 ? 112.375 96.371  138.606 1.00 110.93 ? 206 PHE D CZ  1 
ATOM 6625 N N   . ILE E 5 313 ? 117.360 96.213  140.288 1.00 110.92 ? 207 ILE D N   1 
ATOM 6626 C CA  . ILE E 5 313 ? 117.468 97.667  140.292 1.00 109.74 ? 207 ILE D CA  1 
ATOM 6627 C C   . ILE E 5 313 ? 118.687 98.117  139.500 1.00 108.35 ? 207 ILE D C   1 
ATOM 6628 O O   . ILE E 5 313 ? 118.609 99.062  138.706 1.00 107.65 ? 207 ILE D O   1 
ATOM 6629 C CB  . ILE E 5 313 ? 117.495 98.202  141.734 1.00 109.14 ? 207 ILE D CB  1 
ATOM 6630 C CG1 . ILE E 5 313 ? 116.130 97.993  142.402 1.00 109.10 ? 207 ILE D CG1 1 
ATOM 6631 C CG2 . ILE E 5 313 ? 117.880 99.671  141.745 1.00 107.54 ? 207 ILE D CG2 1 
ATOM 6632 C CD1 . ILE E 5 313 ? 115.014 98.857  141.845 1.00 107.81 ? 207 ILE D CD1 1 
ATOM 6633 N N   . ILE E 5 314 ? 119.828 97.456  139.689 1.00 108.18 ? 208 ILE D N   1 
ATOM 6634 C CA  . ILE E 5 314 ? 121.030 97.859  138.967 1.00 108.47 ? 208 ILE D CA  1 
ATOM 6635 C C   . ILE E 5 314 ? 120.832 97.676  137.467 1.00 108.03 ? 208 ILE D C   1 
ATOM 6636 O O   . ILE E 5 314 ? 121.163 98.561  136.671 1.00 107.78 ? 208 ILE D O   1 
ATOM 6637 C CB  . ILE E 5 314 ? 122.255 97.081  139.481 1.00 108.75 ? 208 ILE D CB  1 
ATOM 6638 C CG1 . ILE E 5 314 ? 122.510 97.394  140.963 1.00 108.29 ? 208 ILE D CG1 1 
ATOM 6639 C CG2 . ILE E 5 314 ? 123.486 97.408  138.649 1.00 107.62 ? 208 ILE D CG2 1 
ATOM 6640 C CD1 . ILE E 5 314 ? 122.784 98.853  141.268 1.00 108.06 ? 208 ILE D CD1 1 
ATOM 6641 N N   . TYR E 5 315 ? 120.281 96.533  137.057 1.00 108.59 ? 209 TYR D N   1 
ATOM 6642 C CA  . TYR E 5 315 ? 120.069 96.278  135.637 1.00 108.79 ? 209 TYR D CA  1 
ATOM 6643 C C   . TYR E 5 315 ? 119.158 97.331  135.020 1.00 108.60 ? 209 TYR D C   1 
ATOM 6644 O O   . TYR E 5 315 ? 119.497 97.944  133.997 1.00 108.36 ? 209 TYR D O   1 
ATOM 6645 C CB  . TYR E 5 315 ? 119.483 94.877  135.458 1.00 109.34 ? 209 TYR D CB  1 
ATOM 6646 C CG  . TYR E 5 315 ? 119.153 94.498  134.036 1.00 109.73 ? 209 TYR D CG  1 
ATOM 6647 C CD1 . TYR E 5 315 ? 120.152 94.125  133.148 1.00 109.33 ? 209 TYR D CD1 1 
ATOM 6648 C CD2 . TYR E 5 315 ? 117.838 94.487  133.588 1.00 109.04 ? 209 TYR D CD2 1 
ATOM 6649 C CE1 . TYR E 5 315 ? 119.854 93.766  131.848 1.00 109.41 ? 209 TYR D CE1 1 
ATOM 6650 C CE2 . TYR E 5 315 ? 117.529 94.128  132.291 1.00 109.58 ? 209 TYR D CE2 1 
ATOM 6651 C CZ  . TYR E 5 315 ? 118.541 93.768  131.425 1.00 109.81 ? 209 TYR D CZ  1 
ATOM 6652 O OH  . TYR E 5 315 ? 118.241 93.411  130.131 1.00 108.94 ? 209 TYR D OH  1 
ATOM 6653 N N   . THR E 5 316 ? 117.991 97.558  135.631 1.00 102.42 ? 210 THR D N   1 
ATOM 6654 C CA  . THR E 5 316 ? 117.034 98.492  135.045 1.00 103.23 ? 210 THR D CA  1 
ATOM 6655 C C   . THR E 5 316 ? 117.600 99.907  135.021 1.00 102.40 ? 210 THR D C   1 
ATOM 6656 O O   . THR E 5 316 ? 117.521 100.596 133.998 1.00 99.90  ? 210 THR D O   1 
ATOM 6657 C CB  . THR E 5 316 ? 115.702 98.443  135.801 1.00 102.60 ? 210 THR D CB  1 
ATOM 6658 O OG1 . THR E 5 316 ? 114.733 99.246  135.117 1.00 100.63 ? 210 THR D OG1 1 
ATOM 6659 C CG2 . THR E 5 316 ? 115.849 98.947  137.223 1.00 102.28 ? 210 THR D CG2 1 
ATOM 6660 N N   . ALA E 5 317 ? 118.208 100.352 136.124 1.00 99.80  ? 211 ALA D N   1 
ATOM 6661 C CA  . ALA E 5 317 ? 118.782 101.691 136.142 1.00 98.23  ? 211 ALA D CA  1 
ATOM 6662 C C   . ALA E 5 317 ? 119.848 101.832 135.067 1.00 97.43  ? 211 ALA D C   1 
ATOM 6663 O O   . ALA E 5 317 ? 119.750 102.703 134.194 1.00 97.03  ? 211 ALA D O   1 
ATOM 6664 C CB  . ALA E 5 317 ? 119.364 101.996 137.521 1.00 98.50  ? 211 ALA D CB  1 
ATOM 6665 N N   . ALA E 5 318 ? 120.850 100.948 135.083 1.00 93.02  ? 212 ALA D N   1 
ATOM 6666 C CA  . ALA E 5 318 ? 121.923 101.018 134.102 1.00 92.05  ? 212 ALA D CA  1 
ATOM 6667 C C   . ALA E 5 318 ? 121.357 101.105 132.695 1.00 91.77  ? 212 ALA D C   1 
ATOM 6668 O O   . ALA E 5 318 ? 121.506 102.127 132.016 1.00 92.68  ? 212 ALA D O   1 
ATOM 6669 C CB  . ALA E 5 318 ? 122.841 99.802  134.243 1.00 92.70  ? 212 ALA D CB  1 
ATOM 6670 N N   . LEU E 5 319 ? 120.637 100.070 132.263 1.00 90.57  ? 213 LEU D N   1 
ATOM 6671 C CA  . LEU E 5 319 ? 120.157 100.062 130.890 1.00 91.42  ? 213 LEU D CA  1 
ATOM 6672 C C   . LEU E 5 319 ? 119.298 101.291 130.631 1.00 91.80  ? 213 LEU D C   1 
ATOM 6673 O O   . LEU E 5 319 ? 119.744 102.232 129.960 1.00 92.10  ? 213 LEU D O   1 
ATOM 6674 C CB  . LEU E 5 319 ? 119.362 98.784  130.607 1.00 92.53  ? 213 LEU D CB  1 
ATOM 6675 C CG  . LEU E 5 319 ? 118.782 98.632  129.197 1.00 93.04  ? 213 LEU D CG  1 
ATOM 6676 C CD1 . LEU E 5 319 ? 119.886 98.394  128.179 1.00 92.53  ? 213 LEU D CD1 1 
ATOM 6677 C CD2 . LEU E 5 319 ? 117.758 97.508  129.156 1.00 92.94  ? 213 LEU D CD2 1 
ATOM 6678 N N   . GLY E 5 320 ? 118.119 101.342 131.259 1.00 85.31  ? 214 GLY D N   1 
ATOM 6679 C CA  . GLY E 5 320 ? 117.090 102.285 130.885 1.00 85.21  ? 214 GLY D CA  1 
ATOM 6680 C C   . GLY E 5 320 ? 117.322 103.711 131.319 1.00 84.08  ? 214 GLY D C   1 
ATOM 6681 O O   . GLY E 5 320 ? 116.424 104.538 131.131 1.00 81.27  ? 214 GLY D O   1 
ATOM 6682 N N   . PHE E 5 321 ? 118.472 104.032 131.909 1.00 79.19  ? 215 PHE D N   1 
ATOM 6683 C CA  . PHE E 5 321 ? 118.853 105.423 132.091 1.00 77.01  ? 215 PHE D CA  1 
ATOM 6684 C C   . PHE E 5 321 ? 120.138 105.769 131.359 1.00 78.84  ? 215 PHE D C   1 
ATOM 6685 O O   . PHE E 5 321 ? 120.167 106.748 130.605 1.00 81.94  ? 215 PHE D O   1 
ATOM 6686 C CB  . PHE E 5 321 ? 118.994 105.744 133.585 1.00 78.28  ? 215 PHE D CB  1 
ATOM 6687 C CG  . PHE E 5 321 ? 119.193 107.203 133.873 1.00 78.83  ? 215 PHE D CG  1 
ATOM 6688 C CD1 . PHE E 5 321 ? 118.258 108.136 133.463 1.00 79.10  ? 215 PHE D CD1 1 
ATOM 6689 C CD2 . PHE E 5 321 ? 120.311 107.643 134.560 1.00 79.38  ? 215 PHE D CD2 1 
ATOM 6690 C CE1 . PHE E 5 321 ? 118.436 109.476 133.726 1.00 78.72  ? 215 PHE D CE1 1 
ATOM 6691 C CE2 . PHE E 5 321 ? 120.493 108.985 134.828 1.00 79.42  ? 215 PHE D CE2 1 
ATOM 6692 C CZ  . PHE E 5 321 ? 119.554 109.901 134.410 1.00 78.49  ? 215 PHE D CZ  1 
ATOM 6693 N N   . PHE E 5 322 ? 121.208 104.997 131.547 1.00 80.11  ? 216 PHE D N   1 
ATOM 6694 C CA  . PHE E 5 322 ? 122.508 105.386 131.032 1.00 80.14  ? 216 PHE D CA  1 
ATOM 6695 C C   . PHE E 5 322 ? 122.774 104.894 129.614 1.00 81.10  ? 216 PHE D C   1 
ATOM 6696 O O   . PHE E 5 322 ? 123.824 105.226 129.056 1.00 81.47  ? 216 PHE D O   1 
ATOM 6697 C CB  . PHE E 5 322 ? 123.603 104.888 131.976 1.00 80.30  ? 216 PHE D CB  1 
ATOM 6698 C CG  . PHE E 5 322 ? 123.461 105.403 133.377 1.00 81.80  ? 216 PHE D CG  1 
ATOM 6699 C CD1 . PHE E 5 322 ? 123.989 106.633 133.736 1.00 81.45  ? 216 PHE D CD1 1 
ATOM 6700 C CD2 . PHE E 5 322 ? 122.788 104.664 134.335 1.00 81.67  ? 216 PHE D CD2 1 
ATOM 6701 C CE1 . PHE E 5 322 ? 123.855 107.110 135.027 1.00 81.35  ? 216 PHE D CE1 1 
ATOM 6702 C CE2 . PHE E 5 322 ? 122.651 105.136 135.627 1.00 81.71  ? 216 PHE D CE2 1 
ATOM 6703 C CZ  . PHE E 5 322 ? 123.186 106.360 135.973 1.00 81.75  ? 216 PHE D CZ  1 
ATOM 6704 N N   . GLY E 5 323 ? 121.871 104.119 129.007 1.00 79.25  ? 217 GLY D N   1 
ATOM 6705 C CA  . GLY E 5 323 ? 121.938 103.905 127.582 1.00 78.67  ? 217 GLY D CA  1 
ATOM 6706 C C   . GLY E 5 323 ? 121.316 105.064 126.826 1.00 78.58  ? 217 GLY D C   1 
ATOM 6707 O O   . GLY E 5 323 ? 121.979 105.770 126.053 1.00 79.07  ? 217 GLY D O   1 
ATOM 6708 N N   . PRO E 5 324 ? 120.017 105.286 127.050 1.00 71.49  ? 218 PRO D N   1 
ATOM 6709 C CA  . PRO E 5 324 ? 119.345 106.404 126.371 1.00 72.67  ? 218 PRO D CA  1 
ATOM 6710 C C   . PRO E 5 324 ? 119.996 107.750 126.624 1.00 71.89  ? 218 PRO D C   1 
ATOM 6711 O O   . PRO E 5 324 ? 120.098 108.558 125.696 1.00 72.99  ? 218 PRO D O   1 
ATOM 6712 C CB  . PRO E 5 324 ? 117.917 106.346 126.939 1.00 71.40  ? 218 PRO D CB  1 
ATOM 6713 C CG  . PRO E 5 324 ? 117.994 105.450 128.123 1.00 71.91  ? 218 PRO D CG  1 
ATOM 6714 C CD  . PRO E 5 324 ? 119.064 104.480 127.825 1.00 70.21  ? 218 PRO D CD  1 
ATOM 6715 N N   . LEU E 5 325 ? 120.445 108.020 127.848 1.00 70.29  ? 219 LEU D N   1 
ATOM 6716 C CA  . LEU E 5 325 ? 121.030 109.324 128.136 1.00 69.84  ? 219 LEU D CA  1 
ATOM 6717 C C   . LEU E 5 325 ? 122.277 109.558 127.293 1.00 71.08  ? 219 LEU D C   1 
ATOM 6718 O O   . LEU E 5 325 ? 122.427 110.610 126.662 1.00 72.33  ? 219 LEU D O   1 
ATOM 6719 C CB  . LEU E 5 325 ? 121.358 109.433 129.625 1.00 71.32  ? 219 LEU D CB  1 
ATOM 6720 C CG  . LEU E 5 325 ? 121.913 110.779 130.096 1.00 71.84  ? 219 LEU D CG  1 
ATOM 6721 C CD1 . LEU E 5 325 ? 120.848 111.859 130.016 1.00 71.11  ? 219 LEU D CD1 1 
ATOM 6722 C CD2 . LEU E 5 325 ? 122.461 110.667 131.506 1.00 72.44  ? 219 LEU D CD2 1 
ATOM 6723 N N   . LEU E 5 326 ? 123.184 108.580 127.269 1.00 71.31  ? 220 LEU D N   1 
ATOM 6724 C CA  . LEU E 5 326 ? 124.415 108.731 126.501 1.00 71.78  ? 220 LEU D CA  1 
ATOM 6725 C C   . LEU E 5 326 ? 124.127 108.820 125.007 1.00 71.19  ? 220 LEU D C   1 
ATOM 6726 O O   . LEU E 5 326 ? 124.727 109.642 124.300 1.00 71.53  ? 220 LEU D O   1 
ATOM 6727 C CB  . LEU E 5 326 ? 125.357 107.564 126.799 1.00 72.65  ? 220 LEU D CB  1 
ATOM 6728 C CG  . LEU E 5 326 ? 126.810 107.720 126.351 1.00 73.08  ? 220 LEU D CG  1 
ATOM 6729 C CD1 . LEU E 5 326 ? 127.510 108.804 127.155 1.00 72.19  ? 220 LEU D CD1 1 
ATOM 6730 C CD2 . LEU E 5 326 ? 127.546 106.395 126.477 1.00 71.43  ? 220 LEU D CD2 1 
ATOM 6731 N N   . VAL E 5 327 ? 123.215 107.983 124.508 1.00 66.36  ? 221 VAL D N   1 
ATOM 6732 C CA  . VAL E 5 327 ? 122.886 108.017 123.085 1.00 64.36  ? 221 VAL D CA  1 
ATOM 6733 C C   . VAL E 5 327 ? 122.343 109.389 122.706 1.00 65.27  ? 221 VAL D C   1 
ATOM 6734 O O   . VAL E 5 327 ? 122.744 109.982 121.696 1.00 66.69  ? 221 VAL D O   1 
ATOM 6735 C CB  . VAL E 5 327 ? 121.884 106.899 122.741 1.00 63.80  ? 221 VAL D CB  1 
ATOM 6736 C CG1 . VAL E 5 327 ? 121.371 107.053 121.319 1.00 64.49  ? 221 VAL D CG1 1 
ATOM 6737 C CG2 . VAL E 5 327 ? 122.530 105.537 122.929 1.00 65.12  ? 221 VAL D CG2 1 
ATOM 6738 N N   . ILE E 5 328 ? 121.424 109.916 123.518 1.00 65.80  ? 222 ILE D N   1 
ATOM 6739 C CA  . ILE E 5 328 ? 120.822 111.215 123.237 1.00 62.80  ? 222 ILE D CA  1 
ATOM 6740 C C   . ILE E 5 328 ? 121.879 112.308 123.281 1.00 62.38  ? 222 ILE D C   1 
ATOM 6741 O O   . ILE E 5 328 ? 121.926 113.189 122.412 1.00 67.05  ? 222 ILE D O   1 
ATOM 6742 C CB  . ILE E 5 328 ? 119.681 111.489 124.233 1.00 62.14  ? 222 ILE D CB  1 
ATOM 6743 C CG1 . ILE E 5 328 ? 118.470 110.623 123.892 1.00 62.85  ? 222 ILE D CG1 1 
ATOM 6744 C CG2 . ILE E 5 328 ? 119.305 112.957 124.238 1.00 61.91  ? 222 ILE D CG2 1 
ATOM 6745 C CD1 . ILE E 5 328 ? 117.480 110.505 125.018 1.00 63.38  ? 222 ILE D CD1 1 
ATOM 6746 N N   . CYS E 5 329 ? 122.740 112.274 124.300 1.00 67.28  ? 223 CYS D N   1 
ATOM 6747 C CA  . CYS E 5 329 ? 123.779 113.289 124.411 1.00 68.12  ? 223 CYS D CA  1 
ATOM 6748 C C   . CYS E 5 329 ? 124.655 113.300 123.168 1.00 68.92  ? 223 CYS D C   1 
ATOM 6749 O O   . CYS E 5 329 ? 124.866 114.352 122.557 1.00 70.89  ? 223 CYS D O   1 
ATOM 6750 C CB  . CYS E 5 329 ? 124.622 113.048 125.663 1.00 68.86  ? 223 CYS D CB  1 
ATOM 6751 S SG  . CYS E 5 329 ? 123.804 113.520 127.206 1.00 75.50  ? 223 CYS D SG  1 
ATOM 6752 N N   . LEU E 5 330 ? 125.150 112.130 122.756 1.00 66.94  ? 224 LEU D N   1 
ATOM 6753 C CA  . LEU E 5 330 ? 126.027 112.082 121.589 1.00 67.22  ? 224 LEU D CA  1 
ATOM 6754 C C   . LEU E 5 330 ? 125.301 112.551 120.334 1.00 67.56  ? 224 LEU D C   1 
ATOM 6755 O O   . LEU E 5 330 ? 125.814 113.395 119.586 1.00 68.46  ? 224 LEU D O   1 
ATOM 6756 C CB  . LEU E 5 330 ? 126.572 110.667 121.392 1.00 67.06  ? 224 LEU D CB  1 
ATOM 6757 C CG  . LEU E 5 330 ? 127.554 110.144 122.442 1.00 69.53  ? 224 LEU D CG  1 
ATOM 6758 C CD1 . LEU E 5 330 ? 128.028 108.752 122.059 1.00 67.72  ? 224 LEU D CD1 1 
ATOM 6759 C CD2 . LEU E 5 330 ? 128.737 111.085 122.619 1.00 67.75  ? 224 LEU D CD2 1 
ATOM 6760 N N   . CYS E 5 331 ? 124.100 112.021 120.086 1.00 59.96  ? 225 CYS D N   1 
ATOM 6761 C CA  . CYS E 5 331 ? 123.383 112.371 118.865 1.00 55.99  ? 225 CYS D CA  1 
ATOM 6762 C C   . CYS E 5 331 ? 123.147 113.872 118.778 1.00 59.03  ? 225 CYS D C   1 
ATOM 6763 O O   . CYS E 5 331 ? 123.491 114.512 117.775 1.00 64.88  ? 225 CYS D O   1 
ATOM 6764 C CB  . CYS E 5 331 ? 122.054 111.621 118.803 1.00 52.17  ? 225 CYS D CB  1 
ATOM 6765 S SG  . CYS E 5 331 ? 122.211 109.841 118.569 1.00 62.13  ? 225 CYS D SG  1 
ATOM 6766 N N   . TYR E 5 332 ? 122.571 114.461 119.827 1.00 52.64  ? 226 TYR D N   1 
ATOM 6767 C CA  . TYR E 5 332 ? 122.215 115.869 119.738 1.00 50.56  ? 226 TYR D CA  1 
ATOM 6768 C C   . TYR E 5 332 ? 123.442 116.767 119.798 1.00 51.45  ? 226 TYR D C   1 
ATOM 6769 O O   . TYR E 5 332 ? 123.448 117.834 119.175 1.00 53.03  ? 226 TYR D O   1 
ATOM 6770 C CB  . TYR E 5 332 ? 121.214 116.226 120.836 1.00 51.23  ? 226 TYR D CB  1 
ATOM 6771 C CG  . TYR E 5 332 ? 119.791 115.792 120.541 1.00 50.76  ? 226 TYR D CG  1 
ATOM 6772 C CD1 . TYR E 5 332 ? 119.237 115.946 119.276 1.00 51.57  ? 226 TYR D CD1 1 
ATOM 6773 C CD2 . TYR E 5 332 ? 119.002 115.232 121.529 1.00 52.37  ? 226 TYR D CD2 1 
ATOM 6774 C CE1 . TYR E 5 332 ? 117.945 115.551 119.008 1.00 49.56  ? 226 TYR D CE1 1 
ATOM 6775 C CE2 . TYR E 5 332 ? 117.708 114.832 121.269 1.00 52.86  ? 226 TYR D CE2 1 
ATOM 6776 C CZ  . TYR E 5 332 ? 117.186 114.995 120.007 1.00 50.84  ? 226 TYR D CZ  1 
ATOM 6777 O OH  . TYR E 5 332 ? 115.897 114.600 119.744 1.00 51.79  ? 226 TYR D OH  1 
ATOM 6778 N N   . LEU E 5 333 ? 124.498 116.353 120.506 1.00 59.75  ? 227 LEU D N   1 
ATOM 6779 C CA  . LEU E 5 333 ? 125.738 117.118 120.477 1.00 60.35  ? 227 LEU D CA  1 
ATOM 6780 C C   . LEU E 5 333 ? 126.308 117.175 119.068 1.00 65.85  ? 227 LEU D C   1 
ATOM 6781 O O   . LEU E 5 333 ? 126.735 118.239 118.604 1.00 67.83  ? 227 LEU D O   1 
ATOM 6782 C CB  . LEU E 5 333 ? 126.753 116.504 121.441 1.00 62.70  ? 227 LEU D CB  1 
ATOM 6783 C CG  . LEU E 5 333 ? 128.124 117.184 121.494 1.00 65.09  ? 227 LEU D CG  1 
ATOM 6784 C CD1 . LEU E 5 333 ? 128.019 118.576 122.101 1.00 63.91  ? 227 LEU D CD1 1 
ATOM 6785 C CD2 . LEU E 5 333 ? 129.112 116.327 122.266 1.00 64.10  ? 227 LEU D CD2 1 
ATOM 6786 N N   . LEU E 5 334 ? 126.322 116.041 118.365 1.00 66.24  ? 228 LEU D N   1 
ATOM 6787 C CA  . LEU E 5 334 ? 126.840 116.045 117.001 1.00 63.79  ? 228 LEU D CA  1 
ATOM 6788 C C   . LEU E 5 334 ? 125.946 116.860 116.075 1.00 63.62  ? 228 LEU D C   1 
ATOM 6789 O O   . LEU E 5 334 ? 126.444 117.577 115.199 1.00 64.16  ? 228 LEU D O   1 
ATOM 6790 C CB  . LEU E 5 334 ? 126.993 114.613 116.492 1.00 62.84  ? 228 LEU D CB  1 
ATOM 6791 C CG  . LEU E 5 334 ? 127.999 113.749 117.261 1.00 64.31  ? 228 LEU D CG  1 
ATOM 6792 C CD1 . LEU E 5 334 ? 128.134 112.386 116.607 1.00 63.42  ? 228 LEU D CD1 1 
ATOM 6793 C CD2 . LEU E 5 334 ? 129.358 114.428 117.375 1.00 63.70  ? 228 LEU D CD2 1 
ATOM 6794 N N   . ILE E 5 335 ? 124.626 116.773 116.255 1.00 62.02  ? 229 ILE D N   1 
ATOM 6795 C CA  . ILE E 5 335 ? 123.720 117.578 115.438 1.00 60.37  ? 229 ILE D CA  1 
ATOM 6796 C C   . ILE E 5 335 ? 124.031 119.060 115.609 1.00 61.05  ? 229 ILE D C   1 
ATOM 6797 O O   . ILE E 5 335 ? 124.179 119.802 114.628 1.00 63.47  ? 229 ILE D O   1 
ATOM 6798 C CB  . ILE E 5 335 ? 122.255 117.264 115.794 1.00 58.51  ? 229 ILE D CB  1 
ATOM 6799 C CG1 . ILE E 5 335 ? 121.858 115.906 115.210 1.00 58.61  ? 229 ILE D CG1 1 
ATOM 6800 C CG2 . ILE E 5 335 ? 121.329 118.383 115.306 1.00 58.31  ? 229 ILE D CG2 1 
ATOM 6801 C CD1 . ILE E 5 335 ? 120.465 115.457 115.568 1.00 60.16  ? 229 ILE D CD1 1 
ATOM 6802 N N   . VAL E 5 336 ? 124.135 119.514 116.860 1.00 69.04  ? 230 VAL D N   1 
ATOM 6803 C CA  . VAL E 5 336 ? 124.354 120.936 117.096 1.00 69.44  ? 230 VAL D CA  1 
ATOM 6804 C C   . VAL E 5 336 ? 125.730 121.356 116.598 1.00 70.71  ? 230 VAL D C   1 
ATOM 6805 O O   . VAL E 5 336 ? 125.891 122.454 116.056 1.00 72.01  ? 230 VAL D O   1 
ATOM 6806 C CB  . VAL E 5 336 ? 124.155 121.291 118.582 1.00 68.35  ? 230 VAL D CB  1 
ATOM 6807 C CG1 . VAL E 5 336 ? 125.094 120.500 119.475 1.00 69.21  ? 230 VAL D CG1 1 
ATOM 6808 C CG2 . VAL E 5 336 ? 124.370 122.779 118.791 1.00 68.95  ? 230 VAL D CG2 1 
ATOM 6809 N N   . VAL E 5 337 ? 126.743 120.502 116.765 1.00 70.03  ? 231 VAL D N   1 
ATOM 6810 C CA  . VAL E 5 337 ? 128.076 120.856 116.284 1.00 72.70  ? 231 VAL D CA  1 
ATOM 6811 C C   . VAL E 5 337 ? 128.066 121.016 114.769 1.00 75.01  ? 231 VAL D C   1 
ATOM 6812 O O   . VAL E 5 337 ? 128.635 121.974 114.225 1.00 74.28  ? 231 VAL D O   1 
ATOM 6813 C CB  . VAL E 5 337 ? 129.104 119.807 116.746 1.00 70.87  ? 231 VAL D CB  1 
ATOM 6814 C CG1 . VAL E 5 337 ? 130.403 119.946 115.964 1.00 71.08  ? 231 VAL D CG1 1 
ATOM 6815 C CG2 . VAL E 5 337 ? 129.362 119.950 118.239 1.00 72.31  ? 231 VAL D CG2 1 
ATOM 6816 N N   . LYS E 5 338 ? 127.411 120.090 114.064 1.00 74.60  ? 232 LYS D N   1 
ATOM 6817 C CA  . LYS E 5 338 ? 127.339 120.183 112.610 1.00 71.83  ? 232 LYS D CA  1 
ATOM 6818 C C   . LYS E 5 338 ? 126.633 121.461 112.178 1.00 70.88  ? 232 LYS D C   1 
ATOM 6819 O O   . LYS E 5 338 ? 127.116 122.183 111.297 1.00 72.12  ? 232 LYS D O   1 
ATOM 6820 C CB  . LYS E 5 338 ? 126.621 118.961 112.038 1.00 71.19  ? 232 LYS D CB  1 
ATOM 6821 C CG  . LYS E 5 338 ? 126.568 118.933 110.520 1.00 71.32  ? 232 LYS D CG  1 
ATOM 6822 C CD  . LYS E 5 338 ? 125.837 117.709 110.001 1.00 72.05  ? 232 LYS D CD  1 
ATOM 6823 C CE  . LYS E 5 338 ? 125.915 117.623 108.488 1.00 70.90  ? 232 LYS D CE  1 
ATOM 6824 N NZ  . LYS E 5 338 ? 127.304 117.364 108.024 1.00 71.21  ? 232 LYS D NZ  1 
ATOM 6825 N N   . VAL E 5 339 ? 125.478 121.754 112.781 1.00 75.96  ? 233 VAL D N   1 
ATOM 6826 C CA  . VAL E 5 339 ? 124.729 122.937 112.365 1.00 77.49  ? 233 VAL D CA  1 
ATOM 6827 C C   . VAL E 5 339 ? 125.530 124.198 112.663 1.00 78.40  ? 233 VAL D C   1 
ATOM 6828 O O   . VAL E 5 339 ? 125.577 125.128 111.848 1.00 77.47  ? 233 VAL D O   1 
ATOM 6829 C CB  . VAL E 5 339 ? 123.343 122.969 113.033 1.00 77.43  ? 233 VAL D CB  1 
ATOM 6830 C CG1 . VAL E 5 339 ? 122.620 124.255 112.679 1.00 76.08  ? 233 VAL D CG1 1 
ATOM 6831 C CG2 . VAL E 5 339 ? 122.517 121.763 112.602 1.00 76.18  ? 233 VAL D CG2 1 
ATOM 6832 N N   . ARG E 5 340 ? 126.175 124.250 113.830 1.00 88.18  ? 234 ARG D N   1 
ATOM 6833 C CA  . ARG E 5 340 ? 127.002 125.400 114.178 1.00 89.29  ? 234 ARG D CA  1 
ATOM 6834 C C   . ARG E 5 340 ? 128.093 125.623 113.140 1.00 88.56  ? 234 ARG D C   1 
ATOM 6835 O O   . ARG E 5 340 ? 128.245 126.731 112.610 1.00 88.70  ? 234 ARG D O   1 
ATOM 6836 C CB  . ARG E 5 340 ? 127.620 125.192 115.561 1.00 88.86  ? 234 ARG D CB  1 
ATOM 6837 C CG  . ARG E 5 340 ? 126.650 125.366 116.713 1.00 88.18  ? 234 ARG D CG  1 
ATOM 6838 C CD  . ARG E 5 340 ? 126.603 126.808 117.182 1.00 89.02  ? 234 ARG D CD  1 
ATOM 6839 N NE  . ARG E 5 340 ? 125.600 127.013 118.219 1.00 90.61  ? 234 ARG D NE  1 
ATOM 6840 C CZ  . ARG E 5 340 ? 125.349 128.178 118.802 1.00 91.06  ? 234 ARG D CZ  1 
ATOM 6841 N NH1 . ARG E 5 340 ? 126.032 129.268 118.495 1.00 91.47  ? 234 ARG D NH1 1 
ATOM 6842 N NH2 . ARG E 5 340 ? 124.385 128.250 119.714 1.00 89.68  ? 234 ARG D NH2 1 
ATOM 6843 N N   . SER E 5 341 ? 128.863 124.576 112.832 1.00 88.69  ? 235 SER D N   1 
ATOM 6844 C CA  . SER E 5 341 ? 129.968 124.737 111.893 1.00 91.07  ? 235 SER D CA  1 
ATOM 6845 C C   . SER E 5 341 ? 129.464 125.139 110.512 1.00 89.79  ? 235 SER D C   1 
ATOM 6846 O O   . SER E 5 341 ? 130.043 126.021 109.861 1.00 88.45  ? 235 SER D O   1 
ATOM 6847 C CB  . SER E 5 341 ? 130.779 123.444 111.815 1.00 89.56  ? 235 SER D CB  1 
ATOM 6848 O OG  . SER E 5 341 ? 131.908 123.597 110.974 1.00 88.10  ? 235 SER D OG  1 
ATOM 6849 N N   . ALA E 5 342 ? 128.384 124.505 110.047 1.00 89.19  ? 236 ALA D N   1 
ATOM 6850 C CA  . ALA E 5 342 ? 127.871 124.806 108.715 1.00 88.79  ? 236 ALA D CA  1 
ATOM 6851 C C   . ALA E 5 342 ? 127.374 126.241 108.622 1.00 90.84  ? 236 ALA D C   1 
ATOM 6852 O O   . ALA E 5 342 ? 127.645 126.936 107.636 1.00 89.97  ? 236 ALA D O   1 
ATOM 6853 C CB  . ALA E 5 342 ? 126.753 123.832 108.354 1.00 88.21  ? 236 ALA D CB  1 
ATOM 6854 N N   . GLY E 5 343 ? 126.642 126.707 109.636 1.00 99.48  ? 237 GLY D N   1 
ATOM 6855 C CA  . GLY E 5 343 ? 126.154 128.073 109.606 1.00 97.96  ? 237 GLY D CA  1 
ATOM 6856 C C   . GLY E 5 343 ? 127.252 129.097 109.796 1.00 98.36  ? 237 GLY D C   1 
ATOM 6857 O O   . GLY E 5 343 ? 127.125 130.238 109.343 1.00 97.84  ? 237 GLY D O   1 
ATOM 6858 N N   . ARG E 5 344 ? 128.343 128.712 110.463 1.00 101.07 ? 238 ARG D N   1 
ATOM 6859 C CA  . ARG E 5 344 ? 129.431 129.654 110.690 1.00 100.49 ? 238 ARG D CA  1 
ATOM 6860 C C   . ARG E 5 344 ? 130.364 129.758 109.491 1.00 101.00 ? 238 ARG D C   1 
ATOM 6861 O O   . ARG E 5 344 ? 130.975 130.812 109.283 1.00 101.79 ? 238 ARG D O   1 
ATOM 6862 C CB  . ARG E 5 344 ? 130.226 129.244 111.930 1.00 99.95  ? 238 ARG D CB  1 
ATOM 6863 C CG  . ARG E 5 344 ? 130.912 130.401 112.644 1.00 100.76 ? 238 ARG D CG  1 
ATOM 6864 C CD  . ARG E 5 344 ? 129.915 131.283 113.387 1.00 101.48 ? 238 ARG D CD  1 
ATOM 6865 N NE  . ARG E 5 344 ? 129.137 130.533 114.365 1.00 102.24 ? 238 ARG D NE  1 
ATOM 6866 C CZ  . ARG E 5 344 ? 128.084 131.011 115.014 1.00 101.29 ? 238 ARG D CZ  1 
ATOM 6867 N NH1 . ARG E 5 344 ? 127.651 132.245 114.818 1.00 100.96 ? 238 ARG D NH1 1 
ATOM 6868 N NH2 . ARG E 5 344 ? 127.446 130.229 115.880 1.00 99.43  ? 238 ARG D NH2 1 
ATOM 6869 N N   . ARG E 5 345 ? 130.490 128.695 108.692 1.00 103.59 ? 239 ARG D N   1 
ATOM 6870 C CA  . ARG E 5 345 ? 131.450 128.724 107.592 1.00 103.52 ? 239 ARG D CA  1 
ATOM 6871 C C   . ARG E 5 345 ? 131.028 129.630 106.440 1.00 103.22 ? 239 ARG D C   1 
ATOM 6872 O O   . ARG E 5 345 ? 131.862 129.921 105.577 1.00 102.61 ? 239 ARG D O   1 
ATOM 6873 C CB  . ARG E 5 345 ? 131.691 127.309 107.055 1.00 103.09 ? 239 ARG D CB  1 
ATOM 6874 C CG  . ARG E 5 345 ? 130.487 126.657 106.379 1.00 103.33 ? 239 ARG D CG  1 
ATOM 6875 C CD  . ARG E 5 345 ? 130.905 125.551 105.414 1.00 103.25 ? 239 ARG D CD  1 
ATOM 6876 N NE  . ARG E 5 345 ? 131.730 124.532 106.055 1.00 104.05 ? 239 ARG D NE  1 
ATOM 6877 C CZ  . ARG E 5 345 ? 133.052 124.449 105.965 1.00 103.66 ? 239 ARG D CZ  1 
ATOM 6878 N NH1 . ARG E 5 345 ? 133.759 125.315 105.255 1.00 103.14 ? 239 ARG D NH1 1 
ATOM 6879 N NH2 . ARG E 5 345 ? 133.683 123.467 106.602 1.00 103.45 ? 239 ARG D NH2 1 
ATOM 6880 N N   . VAL E 5 346 ? 129.777 130.084 106.402 1.00 104.55 ? 240 VAL D N   1 
ATOM 6881 C CA  . VAL E 5 346 ? 129.220 130.771 105.242 1.00 104.41 ? 240 VAL D CA  1 
ATOM 6882 C C   . VAL E 5 346 ? 129.020 132.261 105.509 1.00 105.10 ? 240 VAL D C   1 
ATOM 6883 O O   . VAL E 5 346 ? 129.444 133.100 104.715 1.00 105.09 ? 240 VAL D O   1 
ATOM 6884 C CB  . VAL E 5 346 ? 127.900 130.107 104.784 1.00 104.93 ? 240 VAL D CB  1 
ATOM 6885 C CG1 . VAL E 5 346 ? 126.851 130.121 105.889 1.00 104.46 ? 240 VAL D CG1 1 
ATOM 6886 C CG2 . VAL E 5 346 ? 127.362 130.790 103.533 1.00 103.03 ? 240 VAL D CG2 1 
ATOM 6887 N N   . TRP E 5 347 ? 128.370 132.607 106.619 1.00 113.53 ? 241 TRP D N   1 
ATOM 6888 C CA  . TRP E 5 347 ? 127.922 133.970 106.865 1.00 113.92 ? 241 TRP D CA  1 
ATOM 6889 C C   . TRP E 5 347 ? 128.424 134.468 108.213 1.00 114.54 ? 241 TRP D C   1 
ATOM 6890 O O   . TRP E 5 347 ? 128.708 133.681 109.121 1.00 112.96 ? 241 TRP D O   1 
ATOM 6891 C CB  . TRP E 5 347 ? 126.389 134.053 106.825 1.00 113.27 ? 241 TRP D CB  1 
ATOM 6892 C CG  . TRP E 5 347 ? 125.839 135.408 106.483 1.00 113.85 ? 241 TRP D CG  1 
ATOM 6893 C CD1 . TRP E 5 347 ? 126.506 136.451 105.904 1.00 113.52 ? 241 TRP D CD1 1 
ATOM 6894 C CD2 . TRP E 5 347 ? 124.496 135.864 106.696 1.00 113.82 ? 241 TRP D CD2 1 
ATOM 6895 N NE1 . TRP E 5 347 ? 125.664 137.524 105.748 1.00 113.58 ? 241 TRP D NE1 1 
ATOM 6896 C CE2 . TRP E 5 347 ? 124.425 137.190 106.226 1.00 114.08 ? 241 TRP D CE2 1 
ATOM 6897 C CE3 . TRP E 5 347 ? 123.349 135.279 107.240 1.00 112.67 ? 241 TRP D CE3 1 
ATOM 6898 C CZ2 . TRP E 5 347 ? 123.252 137.940 106.283 1.00 113.21 ? 241 TRP D CZ2 1 
ATOM 6899 C CZ3 . TRP E 5 347 ? 122.188 136.025 107.296 1.00 114.07 ? 241 TRP D CZ3 1 
ATOM 6900 C CH2 . TRP E 5 347 ? 122.147 137.340 106.821 1.00 113.87 ? 241 TRP D CH2 1 
ATOM 6901 N N   . ALA E 5 348 ? 128.527 135.789 108.334 1.00 123.40 ? 242 ALA D N   1 
ATOM 6902 C CA  . ALA E 5 348 ? 128.938 136.424 109.581 1.00 123.78 ? 242 ALA D CA  1 
ATOM 6903 C C   . ALA E 5 348 ? 127.781 136.453 110.573 1.00 123.69 ? 242 ALA D C   1 
ATOM 6904 O O   . ALA E 5 348 ? 126.619 136.316 110.191 1.00 122.76 ? 242 ALA D O   1 
ATOM 6905 C CB  . ALA E 5 348 ? 129.445 137.834 109.315 1.00 122.61 ? 242 ALA D CB  1 
ATOM 6906 N N   . ARG E 5 353 ? 121.825 132.654 110.103 1.00 30.00  ? 247 ARG D N   1 
ATOM 6907 C CA  . ARG E 5 353 ? 123.217 132.431 110.464 1.00 30.00  ? 247 ARG D CA  1 
ATOM 6908 C C   . ARG E 5 353 ? 123.356 132.275 111.975 1.00 30.00  ? 247 ARG D C   1 
ATOM 6909 O O   . ARG E 5 353 ? 123.274 131.165 112.499 1.00 30.00  ? 247 ARG D O   1 
ATOM 6910 C CB  . ARG E 5 353 ? 124.088 133.584 109.962 1.00 30.00  ? 247 ARG D CB  1 
ATOM 6911 N N   . ARG E 5 354 ? 123.586 133.390 112.673 1.00 114.02 ? 248 ARG D N   1 
ATOM 6912 C CA  . ARG E 5 354 ? 123.667 133.344 114.129 1.00 113.02 ? 248 ARG D CA  1 
ATOM 6913 C C   . ARG E 5 354 ? 122.325 132.963 114.745 1.00 113.24 ? 248 ARG D C   1 
ATOM 6914 O O   . ARG E 5 354 ? 122.271 132.172 115.693 1.00 112.73 ? 248 ARG D O   1 
ATOM 6915 C CB  . ARG E 5 354 ? 124.135 134.696 114.669 1.00 113.06 ? 248 ARG D CB  1 
ATOM 6916 C CG  . ARG E 5 354 ? 125.567 135.061 114.302 1.00 113.40 ? 248 ARG D CG  1 
ATOM 6917 C CD  . ARG E 5 354 ? 125.971 136.389 114.925 1.00 113.01 ? 248 ARG D CD  1 
ATOM 6918 N NE  . ARG E 5 354 ? 127.315 136.810 114.544 1.00 113.25 ? 248 ARG D NE  1 
ATOM 6919 C CZ  . ARG E 5 354 ? 127.864 137.967 114.891 1.00 113.49 ? 248 ARG D CZ  1 
ATOM 6920 N NH1 . ARG E 5 354 ? 127.211 138.850 115.629 1.00 113.14 ? 248 ARG D NH1 1 
ATOM 6921 N NH2 . ARG E 5 354 ? 129.100 138.246 114.486 1.00 113.59 ? 248 ARG D NH2 1 
ATOM 6922 N N   . ARG E 5 355 ? 121.230 133.511 114.209 1.00 118.94 ? 249 ARG D N   1 
ATOM 6923 C CA  . ARG E 5 355 ? 119.917 133.315 114.819 1.00 120.01 ? 249 ARG D CA  1 
ATOM 6924 C C   . ARG E 5 355 ? 119.517 131.846 114.831 1.00 119.86 ? 249 ARG D C   1 
ATOM 6925 O O   . ARG E 5 355 ? 118.986 131.346 115.831 1.00 119.57 ? 249 ARG D O   1 
ATOM 6926 C CB  . ARG E 5 355 ? 118.873 134.139 114.065 1.00 119.36 ? 249 ARG D CB  1 
ATOM 6927 C CG  . ARG E 5 355 ? 117.427 133.871 114.468 1.00 119.41 ? 249 ARG D CG  1 
ATOM 6928 C CD  . ARG E 5 355 ? 117.206 134.044 115.960 1.00 118.86 ? 249 ARG D CD  1 
ATOM 6929 N NE  . ARG E 5 355 ? 115.795 133.929 116.313 1.00 118.74 ? 249 ARG D NE  1 
ATOM 6930 C CZ  . ARG E 5 355 ? 114.941 134.943 116.355 1.00 118.92 ? 249 ARG D CZ  1 
ATOM 6931 N NH1 . ARG E 5 355 ? 115.321 136.184 116.099 1.00 118.91 ? 249 ARG D NH1 1 
ATOM 6932 N NH2 . ARG E 5 355 ? 113.670 134.705 116.666 1.00 118.65 ? 249 ARG D NH2 1 
ATOM 6933 N N   . ARG E 5 356 ? 119.752 131.142 113.725 1.00 116.18 ? 250 ARG D N   1 
ATOM 6934 C CA  . ARG E 5 356 ? 119.359 129.742 113.628 1.00 116.08 ? 250 ARG D CA  1 
ATOM 6935 C C   . ARG E 5 356 ? 120.280 128.844 114.432 1.00 115.92 ? 250 ARG D C   1 
ATOM 6936 O O   . ARG E 5 356 ? 119.849 127.794 114.921 1.00 115.19 ? 250 ARG D O   1 
ATOM 6937 C CB  . ARG E 5 356 ? 119.369 129.289 112.172 1.00 116.21 ? 250 ARG D CB  1 
ATOM 6938 C CG  . ARG E 5 356 ? 118.201 129.775 111.352 1.00 116.42 ? 250 ARG D CG  1 
ATOM 6939 C CD  . ARG E 5 356 ? 118.248 129.181 109.954 1.00 117.16 ? 250 ARG D CD  1 
ATOM 6940 N NE  . ARG E 5 356 ? 119.531 129.387 109.292 1.00 117.01 ? 250 ARG D NE  1 
ATOM 6941 C CZ  . ARG E 5 356 ? 119.902 130.506 108.685 1.00 117.32 ? 250 ARG D CZ  1 
ATOM 6942 N NH1 . ARG E 5 356 ? 119.134 131.583 108.687 1.00 116.54 ? 250 ARG D NH1 1 
ATOM 6943 N NH2 . ARG E 5 356 ? 121.077 130.546 108.062 1.00 117.05 ? 250 ARG D NH2 1 
ATOM 6944 N N   . SER E 5 357 ? 121.551 129.222 114.542 1.00 104.79 ? 251 SER D N   1 
ATOM 6945 C CA  . SER E 5 357 ? 122.466 128.517 115.422 1.00 103.30 ? 251 SER D CA  1 
ATOM 6946 C C   . SER E 5 357 ? 122.072 128.660 116.884 1.00 103.04 ? 251 SER D C   1 
ATOM 6947 O O   . SER E 5 357 ? 122.362 127.762 117.682 1.00 103.23 ? 251 SER D O   1 
ATOM 6948 C CB  . SER E 5 357 ? 123.883 129.048 115.217 1.00 103.12 ? 251 SER D CB  1 
ATOM 6949 O OG  . SER E 5 357 ? 123.900 130.461 115.322 1.00 102.97 ? 251 SER D OG  1 
ATOM 6950 N N   . GLU E 5 358 ? 121.388 129.748 117.244 1.00 98.90  ? 252 GLU D N   1 
ATOM 6951 C CA  . GLU E 5 358 ? 121.147 130.097 118.640 1.00 99.13  ? 252 GLU D CA  1 
ATOM 6952 C C   . GLU E 5 358 ? 119.766 129.670 119.126 1.00 100.10 ? 252 GLU D C   1 
ATOM 6953 O O   . GLU E 5 358 ? 119.659 128.940 120.115 1.00 98.90  ? 252 GLU D O   1 
ATOM 6954 C CB  . GLU E 5 358 ? 121.318 131.611 118.836 1.00 98.88  ? 252 GLU D CB  1 
ATOM 6955 C CG  . GLU E 5 358 ? 122.755 132.102 118.803 1.00 98.43  ? 252 GLU D CG  1 
ATOM 6956 C CD  . GLU E 5 358 ? 123.571 131.591 119.969 1.00 99.60  ? 252 GLU D CD  1 
ATOM 6957 O OE1 . GLU E 5 358 ? 122.966 131.153 120.970 1.00 99.61  ? 252 GLU D OE1 1 
ATOM 6958 O OE2 . GLU E 5 358 ? 124.816 131.625 119.886 1.00 98.73  ? 252 GLU D OE2 1 
ATOM 6959 N N   . ARG E 5 359 ? 118.698 130.119 118.456 1.00 102.76 ? 253 ARG D N   1 
ATOM 6960 C CA  . ARG E 5 359 ? 117.376 130.000 119.064 1.00 102.23 ? 253 ARG D CA  1 
ATOM 6961 C C   . ARG E 5 359 ? 116.823 128.583 119.055 1.00 101.52 ? 253 ARG D C   1 
ATOM 6962 O O   . ARG E 5 359 ? 116.106 128.219 119.990 1.00 102.89 ? 253 ARG D O   1 
ATOM 6963 C CB  . ARG E 5 359 ? 116.350 130.904 118.375 1.00 102.33 ? 253 ARG D CB  1 
ATOM 6964 C CG  . ARG E 5 359 ? 115.104 131.105 119.247 1.00 102.95 ? 253 ARG D CG  1 
ATOM 6965 C CD  . ARG E 5 359 ? 113.862 131.612 118.512 1.00 103.07 ? 253 ARG D CD  1 
ATOM 6966 N NE  . ARG E 5 359 ? 113.572 130.942 117.250 1.00 102.45 ? 253 ARG D NE  1 
ATOM 6967 C CZ  . ARG E 5 359 ? 112.554 131.269 116.463 1.00 101.95 ? 253 ARG D CZ  1 
ATOM 6968 N NH1 . ARG E 5 359 ? 111.706 132.229 116.794 1.00 101.48 ? 253 ARG D NH1 1 
ATOM 6969 N NH2 . ARG E 5 359 ? 112.381 130.617 115.316 1.00 102.67 ? 253 ARG D NH2 1 
ATOM 6970 N N   . ARG E 5 360 ? 117.122 127.774 118.042 1.00 93.61  ? 254 ARG D N   1 
ATOM 6971 C CA  . ARG E 5 360 ? 116.455 126.487 117.893 1.00 93.14  ? 254 ARG D CA  1 
ATOM 6972 C C   . ARG E 5 360 ? 117.338 125.329 118.334 1.00 93.78  ? 254 ARG D C   1 
ATOM 6973 O O   . ARG E 5 360 ? 116.972 124.576 119.241 1.00 94.15  ? 254 ARG D O   1 
ATOM 6974 C CB  . ARG E 5 360 ? 116.017 126.283 116.438 1.00 93.45  ? 254 ARG D CB  1 
ATOM 6975 C CG  . ARG E 5 360 ? 115.128 125.069 116.231 1.00 94.52  ? 254 ARG D CG  1 
ATOM 6976 C CD  . ARG E 5 360 ? 113.811 125.226 116.943 1.00 95.35  ? 254 ARG D CD  1 
ATOM 6977 N NE  . ARG E 5 360 ? 112.888 124.148 116.625 1.00 95.90  ? 254 ARG D NE  1 
ATOM 6978 C CZ  . ARG E 5 360 ? 111.575 124.218 116.782 1.00 95.17  ? 254 ARG D CZ  1 
ATOM 6979 N NH1 . ARG E 5 360 ? 110.997 125.285 117.310 1.00 94.01  ? 254 ARG D NH1 1 
ATOM 6980 N NH2 . ARG E 5 360 ? 110.824 123.199 116.384 1.00 93.38  ? 254 ARG D NH2 1 
ATOM 6981 N N   . VAL E 5 361 ? 118.523 125.195 117.740 1.00 84.29  ? 255 VAL D N   1 
ATOM 6982 C CA  . VAL E 5 361 ? 119.337 124.013 117.970 1.00 82.86  ? 255 VAL D CA  1 
ATOM 6983 C C   . VAL E 5 361 ? 119.887 123.980 119.389 1.00 83.71  ? 255 VAL D C   1 
ATOM 6984 O O   . VAL E 5 361 ? 120.161 122.896 119.916 1.00 85.75  ? 255 VAL D O   1 
ATOM 6985 C CB  . VAL E 5 361 ? 120.461 123.957 116.920 1.00 83.82  ? 255 VAL D CB  1 
ATOM 6986 C CG1 . VAL E 5 361 ? 121.247 122.667 117.041 1.00 84.32  ? 255 VAL D CG1 1 
ATOM 6987 C CG2 . VAL E 5 361 ? 119.880 124.102 115.514 1.00 82.85  ? 255 VAL D CG2 1 
ATOM 6988 N N   . THR E 5 362 ? 120.051 125.134 120.031 1.00 81.00  ? 256 THR D N   1 
ATOM 6989 C CA  . THR E 5 362 ? 120.422 125.146 121.439 1.00 81.52  ? 256 THR D CA  1 
ATOM 6990 C C   . THR E 5 362 ? 119.203 124.959 122.332 1.00 82.13  ? 256 THR D C   1 
ATOM 6991 O O   . THR E 5 362 ? 119.201 124.089 123.206 1.00 80.64  ? 256 THR D O   1 
ATOM 6992 C CB  . THR E 5 362 ? 121.127 126.455 121.804 1.00 82.89  ? 256 THR D CB  1 
ATOM 6993 O OG1 . THR E 5 362 ? 122.243 126.665 120.934 1.00 82.69  ? 256 THR D OG1 1 
ATOM 6994 C CG2 . THR E 5 362 ? 121.621 126.413 123.249 1.00 81.78  ? 256 THR D CG2 1 
ATOM 6995 N N   . ARG E 5 363 ? 118.162 125.767 122.126 1.00 86.03  ? 257 ARG D N   1 
ATOM 6996 C CA  . ARG E 5 363 ? 117.048 125.777 123.067 1.00 84.09  ? 257 ARG D CA  1 
ATOM 6997 C C   . ARG E 5 363 ? 116.305 124.447 123.069 1.00 83.86  ? 257 ARG D C   1 
ATOM 6998 O O   . ARG E 5 363 ? 116.062 123.874 124.133 1.00 86.52  ? 257 ARG D O   1 
ATOM 6999 C CB  . ARG E 5 363 ? 116.099 126.931 122.753 1.00 83.97  ? 257 ARG D CB  1 
ATOM 7000 C CG  . ARG E 5 363 ? 116.726 128.294 122.984 1.00 85.99  ? 257 ARG D CG  1 
ATOM 7001 C CD  . ARG E 5 363 ? 115.718 129.421 122.904 1.00 86.52  ? 257 ARG D CD  1 
ATOM 7002 N NE  . ARG E 5 363 ? 116.381 130.719 122.949 1.00 87.40  ? 257 ARG D NE  1 
ATOM 7003 C CZ  . ARG E 5 363 ? 115.760 131.889 122.877 1.00 86.86  ? 257 ARG D CZ  1 
ATOM 7004 N NH1 . ARG E 5 363 ? 114.445 131.970 122.757 1.00 85.58  ? 257 ARG D NH1 1 
ATOM 7005 N NH2 . ARG E 5 363 ? 116.479 133.006 122.927 1.00 85.78  ? 257 ARG D NH2 1 
ATOM 7006 N N   . MET E 5 364 ? 115.934 123.934 121.893 1.00 76.66  ? 258 MET D N   1 
ATOM 7007 C CA  . MET E 5 364 ? 115.179 122.684 121.847 1.00 76.32  ? 258 MET D CA  1 
ATOM 7008 C C   . MET E 5 364 ? 116.000 121.517 122.388 1.00 76.90  ? 258 MET D C   1 
ATOM 7009 O O   . MET E 5 364 ? 115.493 120.680 123.146 1.00 78.29  ? 258 MET D O   1 
ATOM 7010 C CB  . MET E 5 364 ? 114.733 122.405 120.415 1.00 78.75  ? 258 MET D CB  1 
ATOM 7011 C CG  . MET E 5 364 ? 113.631 123.322 119.927 1.00 79.66  ? 258 MET D CG  1 
ATOM 7012 S SD  . MET E 5 364 ? 112.006 122.848 120.536 1.00 82.36  ? 258 MET D SD  1 
ATOM 7013 C CE  . MET E 5 364 ? 111.710 121.371 119.569 1.00 79.94  ? 258 MET D CE  1 
ATOM 7014 N N   . VAL E 5 365 ? 117.271 121.434 121.992 1.00 68.62  ? 259 VAL D N   1 
ATOM 7015 C CA  . VAL E 5 365 ? 118.112 120.322 122.427 1.00 65.37  ? 259 VAL D CA  1 
ATOM 7016 C C   . VAL E 5 365 ? 118.315 120.372 123.935 1.00 68.58  ? 259 VAL D C   1 
ATOM 7017 O O   . VAL E 5 365 ? 118.193 119.356 124.636 1.00 70.69  ? 259 VAL D O   1 
ATOM 7018 C CB  . VAL E 5 365 ? 119.454 120.344 121.674 1.00 64.57  ? 259 VAL D CB  1 
ATOM 7019 C CG1 . VAL E 5 365 ? 120.458 119.428 122.349 1.00 65.78  ? 259 VAL D CG1 1 
ATOM 7020 C CG2 . VAL E 5 365 ? 119.249 119.949 120.218 1.00 65.79  ? 259 VAL D CG2 1 
ATOM 7021 N N   . VAL E 5 366 ? 118.640 121.554 124.460 1.00 69.46  ? 260 VAL D N   1 
ATOM 7022 C CA  . VAL E 5 366 ? 118.802 121.699 125.899 1.00 67.49  ? 260 VAL D CA  1 
ATOM 7023 C C   . VAL E 5 366 ? 117.497 121.373 126.604 1.00 66.56  ? 260 VAL D C   1 
ATOM 7024 O O   . VAL E 5 366 ? 117.494 120.751 127.668 1.00 67.51  ? 260 VAL D O   1 
ATOM 7025 C CB  . VAL E 5 366 ? 119.299 123.116 126.239 1.00 68.88  ? 260 VAL D CB  1 
ATOM 7026 C CG1 . VAL E 5 366 ? 119.211 123.370 127.735 1.00 69.26  ? 260 VAL D CG1 1 
ATOM 7027 C CG2 . VAL E 5 366 ? 120.727 123.307 125.747 1.00 69.90  ? 260 VAL D CG2 1 
ATOM 7028 N N   . ALA E 5 367 ? 116.367 121.764 126.015 1.00 61.67  ? 261 ALA D N   1 
ATOM 7029 C CA  . ALA E 5 367 ? 115.080 121.469 126.627 1.00 61.22  ? 261 ALA D CA  1 
ATOM 7030 C C   . ALA E 5 367 ? 114.881 119.970 126.772 1.00 63.64  ? 261 ALA D C   1 
ATOM 7031 O O   . ALA E 5 367 ? 114.589 119.477 127.866 1.00 67.93  ? 261 ALA D O   1 
ATOM 7032 C CB  . ALA E 5 367 ? 113.953 122.080 125.797 1.00 63.83  ? 261 ALA D CB  1 
ATOM 7033 N N   . VAL E 5 368 ? 115.054 119.222 125.682 1.00 65.65  ? 262 VAL D N   1 
ATOM 7034 C CA  . VAL E 5 368 ? 114.790 117.785 125.743 1.00 63.02  ? 262 VAL D CA  1 
ATOM 7035 C C   . VAL E 5 368 ? 115.747 117.111 126.722 1.00 60.94  ? 262 VAL D C   1 
ATOM 7036 O O   . VAL E 5 368 ? 115.327 116.329 127.588 1.00 62.51  ? 262 VAL D O   1 
ATOM 7037 C CB  . VAL E 5 368 ? 114.860 117.151 124.339 1.00 63.78  ? 262 VAL D CB  1 
ATOM 7038 C CG1 . VAL E 5 368 ? 113.808 117.766 123.431 1.00 64.85  ? 262 VAL D CG1 1 
ATOM 7039 C CG2 . VAL E 5 368 ? 116.233 117.297 123.718 1.00 64.12  ? 262 VAL D CG2 1 
ATOM 7040 N N   . VAL E 5 369 ? 117.041 117.433 126.634 1.00 60.69  ? 263 VAL D N   1 
ATOM 7041 C CA  . VAL E 5 369 ? 118.022 116.752 127.477 1.00 58.90  ? 263 VAL D CA  1 
ATOM 7042 C C   . VAL E 5 369 ? 117.802 117.100 128.946 1.00 61.80  ? 263 VAL D C   1 
ATOM 7043 O O   . VAL E 5 369 ? 117.800 116.219 129.818 1.00 63.81  ? 263 VAL D O   1 
ATOM 7044 C CB  . VAL E 5 369 ? 119.450 117.101 127.022 1.00 59.23  ? 263 VAL D CB  1 
ATOM 7045 C CG1 . VAL E 5 369 ? 120.473 116.532 127.990 1.00 60.42  ? 263 VAL D CG1 1 
ATOM 7046 C CG2 . VAL E 5 369 ? 119.698 116.582 125.614 1.00 61.66  ? 263 VAL D CG2 1 
ATOM 7047 N N   . ALA E 5 370 ? 117.635 118.391 129.247 1.00 66.98  ? 264 ALA D N   1 
ATOM 7048 C CA  . ALA E 5 370 ? 117.455 118.821 130.626 1.00 64.82  ? 264 ALA D CA  1 
ATOM 7049 C C   . ALA E 5 370 ? 116.175 118.255 131.215 1.00 64.26  ? 264 ALA D C   1 
ATOM 7050 O O   . ALA E 5 370 ? 116.162 117.809 132.364 1.00 67.58  ? 264 ALA D O   1 
ATOM 7051 C CB  . ALA E 5 370 ? 117.445 120.347 130.699 1.00 63.22  ? 264 ALA D CB  1 
ATOM 7052 N N   . LEU E 5 371 ? 115.082 118.269 130.451 1.00 62.43  ? 265 LEU D N   1 
ATOM 7053 C CA  . LEU E 5 371 ? 113.838 117.702 130.951 1.00 64.13  ? 265 LEU D CA  1 
ATOM 7054 C C   . LEU E 5 371 ? 114.017 116.225 131.273 1.00 67.37  ? 265 LEU D C   1 
ATOM 7055 O O   . LEU E 5 371 ? 113.634 115.763 132.356 1.00 69.32  ? 265 LEU D O   1 
ATOM 7056 C CB  . LEU E 5 371 ? 112.730 117.906 129.918 1.00 64.27  ? 265 LEU D CB  1 
ATOM 7057 C CG  . LEU E 5 371 ? 111.281 117.803 130.392 1.00 64.07  ? 265 LEU D CG  1 
ATOM 7058 C CD1 . LEU E 5 371 ? 110.918 118.984 131.275 1.00 65.61  ? 265 LEU D CD1 1 
ATOM 7059 C CD2 . LEU E 5 371 ? 110.348 117.717 129.197 1.00 63.58  ? 265 LEU D CD2 1 
ATOM 7060 N N   . PHE E 5 372 ? 114.628 115.472 130.354 1.00 66.82  ? 266 PHE D N   1 
ATOM 7061 C CA  . PHE E 5 372 ? 114.814 114.043 130.582 1.00 62.64  ? 266 PHE D CA  1 
ATOM 7062 C C   . PHE E 5 372 ? 115.616 113.793 131.853 1.00 65.00  ? 266 PHE D C   1 
ATOM 7063 O O   . PHE E 5 372 ? 115.188 113.037 132.736 1.00 68.39  ? 266 PHE D O   1 
ATOM 7064 C CB  . PHE E 5 372 ? 115.508 113.419 129.372 1.00 63.32  ? 266 PHE D CB  1 
ATOM 7065 C CG  . PHE E 5 372 ? 115.634 111.927 129.444 1.00 65.50  ? 266 PHE D CG  1 
ATOM 7066 C CD1 . PHE E 5 372 ? 114.587 111.110 129.052 1.00 66.87  ? 266 PHE D CD1 1 
ATOM 7067 C CD2 . PHE E 5 372 ? 116.806 111.339 129.885 1.00 65.54  ? 266 PHE D CD2 1 
ATOM 7068 C CE1 . PHE E 5 372 ? 114.705 109.737 129.110 1.00 63.36  ? 266 PHE D CE1 1 
ATOM 7069 C CE2 . PHE E 5 372 ? 116.927 109.964 129.945 1.00 64.25  ? 266 PHE D CE2 1 
ATOM 7070 C CZ  . PHE E 5 372 ? 115.876 109.165 129.557 1.00 63.45  ? 266 PHE D CZ  1 
ATOM 7071 N N   . VAL E 5 373 ? 116.782 114.432 131.972 1.00 67.29  ? 267 VAL D N   1 
ATOM 7072 C CA  . VAL E 5 373 ? 117.640 114.162 133.123 1.00 66.06  ? 267 VAL D CA  1 
ATOM 7073 C C   . VAL E 5 373 ? 116.970 114.621 134.412 1.00 66.21  ? 267 VAL D C   1 
ATOM 7074 O O   . VAL E 5 373 ? 116.957 113.893 135.410 1.00 69.17  ? 267 VAL D O   1 
ATOM 7075 C CB  . VAL E 5 373 ? 119.023 114.815 132.934 1.00 67.45  ? 267 VAL D CB  1 
ATOM 7076 C CG1 . VAL E 5 373 ? 118.909 116.329 132.876 1.00 68.76  ? 267 VAL D CG1 1 
ATOM 7077 C CG2 . VAL E 5 373 ? 119.967 114.391 134.050 1.00 65.99  ? 267 VAL D CG2 1 
ATOM 7078 N N   . LEU E 5 374 ? 116.386 115.821 134.414 1.00 70.99  ? 268 LEU D N   1 
ATOM 7079 C CA  . LEU E 5 374 ? 115.785 116.354 135.629 1.00 73.13  ? 268 LEU D CA  1 
ATOM 7080 C C   . LEU E 5 374 ? 114.616 115.505 136.099 1.00 72.45  ? 268 LEU D C   1 
ATOM 7081 O O   . LEU E 5 374 ? 114.410 115.361 137.308 1.00 74.12  ? 268 LEU D O   1 
ATOM 7082 C CB  . LEU E 5 374 ? 115.328 117.794 135.390 1.00 71.30  ? 268 LEU D CB  1 
ATOM 7083 C CG  . LEU E 5 374 ? 114.523 118.471 136.501 1.00 70.41  ? 268 LEU D CG  1 
ATOM 7084 C CD1 . LEU E 5 374 ? 115.321 118.532 137.791 1.00 71.49  ? 268 LEU D CD1 1 
ATOM 7085 C CD2 . LEU E 5 374 ? 114.099 119.863 136.063 1.00 73.22  ? 268 LEU D CD2 1 
ATOM 7086 N N   . CYS E 5 375 ? 113.837 114.943 135.176 1.00 73.26  ? 269 CYS D N   1 
ATOM 7087 C CA  . CYS E 5 375 ? 112.657 114.190 135.566 1.00 74.29  ? 269 CYS D CA  1 
ATOM 7088 C C   . CYS E 5 375 ? 112.922 112.705 135.777 1.00 76.30  ? 269 CYS D C   1 
ATOM 7089 O O   . CYS E 5 375 ? 112.065 112.026 136.351 1.00 77.13  ? 269 CYS D O   1 
ATOM 7090 C CB  . CYS E 5 375 ? 111.561 114.362 134.518 1.00 75.12  ? 269 CYS D CB  1 
ATOM 7091 S SG  . CYS E 5 375 ? 110.922 116.050 134.391 1.00 81.38  ? 269 CYS D SG  1 
ATOM 7092 N N   . TRP E 5 376 ? 114.069 112.178 135.341 1.00 75.57  ? 270 TRP D N   1 
ATOM 7093 C CA  . TRP E 5 376 ? 114.379 110.771 135.564 1.00 74.21  ? 270 TRP D CA  1 
ATOM 7094 C C   . TRP E 5 376 ? 115.560 110.533 136.497 1.00 74.77  ? 270 TRP D C   1 
ATOM 7095 O O   . TRP E 5 376 ? 115.881 109.371 136.771 1.00 74.39  ? 270 TRP D O   1 
ATOM 7096 C CB  . TRP E 5 376 ? 114.647 110.067 134.227 1.00 75.26  ? 270 TRP D CB  1 
ATOM 7097 C CG  . TRP E 5 376 ? 113.404 109.771 133.443 1.00 74.82  ? 270 TRP D CG  1 
ATOM 7098 C CD1 . TRP E 5 376 ? 112.869 110.524 132.443 1.00 75.52  ? 270 TRP D CD1 1 
ATOM 7099 C CD2 . TRP E 5 376 ? 112.543 108.637 133.593 1.00 75.79  ? 270 TRP D CD2 1 
ATOM 7100 N NE1 . TRP E 5 376 ? 111.729 109.930 131.960 1.00 73.17  ? 270 TRP D NE1 1 
ATOM 7101 C CE2 . TRP E 5 376 ? 111.507 108.770 132.651 1.00 74.74  ? 270 TRP D CE2 1 
ATOM 7102 C CE3 . TRP E 5 376 ? 112.546 107.521 134.434 1.00 78.35  ? 270 TRP D CE3 1 
ATOM 7103 C CZ2 . TRP E 5 376 ? 110.487 107.833 132.524 1.00 75.90  ? 270 TRP D CZ2 1 
ATOM 7104 C CZ3 . TRP E 5 376 ? 111.533 106.593 134.308 1.00 77.83  ? 270 TRP D CZ3 1 
ATOM 7105 C CH2 . TRP E 5 376 ? 110.518 106.754 133.361 1.00 77.25  ? 270 TRP D CH2 1 
ATOM 7106 N N   . MET E 5 377 ? 116.214 111.577 136.998 1.00 84.92  ? 271 MET D N   1 
ATOM 7107 C CA  . MET E 5 377 ? 117.331 111.379 137.912 1.00 85.87  ? 271 MET D CA  1 
ATOM 7108 C C   . MET E 5 377 ? 116.859 111.091 139.335 1.00 88.41  ? 271 MET D C   1 
ATOM 7109 O O   . MET E 5 377 ? 117.367 110.153 139.968 1.00 88.73  ? 271 MET D O   1 
ATOM 7110 C CB  . MET E 5 377 ? 118.248 112.604 137.889 1.00 87.51  ? 271 MET D CB  1 
ATOM 7111 C CG  . MET E 5 377 ? 119.425 112.528 138.842 1.00 87.50  ? 271 MET D CG  1 
ATOM 7112 S SD  . MET E 5 377 ? 120.569 113.908 138.633 1.00 92.43  ? 271 MET D SD  1 
ATOM 7113 C CE  . MET E 5 377 ? 119.528 115.294 139.088 1.00 86.59  ? 271 MET D CE  1 
ATOM 7114 N N   . PRO E 5 378 ? 115.916 111.872 139.887 1.00 85.58  ? 272 PRO D N   1 
ATOM 7115 C CA  . PRO E 5 378 ? 115.508 111.623 141.281 1.00 84.75  ? 272 PRO D CA  1 
ATOM 7116 C C   . PRO E 5 378 ? 115.003 110.212 141.520 1.00 85.57  ? 272 PRO D C   1 
ATOM 7117 O O   . PRO E 5 378 ? 115.344 109.595 142.535 1.00 86.28  ? 272 PRO D O   1 
ATOM 7118 C CB  . PRO E 5 378 ? 114.403 112.665 141.512 1.00 84.45  ? 272 PRO D CB  1 
ATOM 7119 C CG  . PRO E 5 378 ? 114.627 113.705 140.490 1.00 83.72  ? 272 PRO D CG  1 
ATOM 7120 C CD  . PRO E 5 378 ? 115.155 112.985 139.297 1.00 83.83  ? 272 PRO D CD  1 
ATOM 7121 N N   . PHE E 5 379 ? 114.216 109.674 140.590 1.00 85.85  ? 273 PHE D N   1 
ATOM 7122 C CA  . PHE E 5 379 ? 113.658 108.339 140.764 1.00 85.08  ? 273 PHE D CA  1 
ATOM 7123 C C   . PHE E 5 379 ? 114.763 107.297 140.912 1.00 86.14  ? 273 PHE D C   1 
ATOM 7124 O O   . PHE E 5 379 ? 114.788 106.527 141.884 1.00 87.66  ? 273 PHE D O   1 
ATOM 7125 C CB  . PHE E 5 379 ? 112.754 108.027 139.572 1.00 83.61  ? 273 PHE D CB  1 
ATOM 7126 C CG  . PHE E 5 379 ? 112.241 106.625 139.540 1.00 84.45  ? 273 PHE D CG  1 
ATOM 7127 C CD1 . PHE E 5 379 ? 111.122 106.267 140.266 1.00 87.76  ? 273 PHE D CD1 1 
ATOM 7128 C CD2 . PHE E 5 379 ? 112.862 105.668 138.760 1.00 85.31  ? 273 PHE D CD2 1 
ATOM 7129 C CE1 . PHE E 5 379 ? 110.643 104.977 140.227 1.00 88.48  ? 273 PHE D CE1 1 
ATOM 7130 C CE2 . PHE E 5 379 ? 112.387 104.377 138.718 1.00 86.75  ? 273 PHE D CE2 1 
ATOM 7131 C CZ  . PHE E 5 379 ? 111.277 104.031 139.452 1.00 88.24  ? 273 PHE D CZ  1 
ATOM 7132 N N   . TYR E 5 380 ? 115.706 107.278 139.969 1.00 88.47  ? 274 TYR D N   1 
ATOM 7133 C CA  . TYR E 5 380 ? 116.731 106.242 139.978 1.00 87.70  ? 274 TYR D CA  1 
ATOM 7134 C C   . TYR E 5 380 ? 117.721 106.443 141.117 1.00 88.22  ? 274 TYR D C   1 
ATOM 7135 O O   . TYR E 5 380 ? 118.174 105.466 141.723 1.00 88.26  ? 274 TYR D O   1 
ATOM 7136 C CB  . TYR E 5 380 ? 117.448 106.200 138.630 1.00 86.64  ? 274 TYR D CB  1 
ATOM 7137 C CG  . TYR E 5 380 ? 116.634 105.519 137.557 1.00 86.31  ? 274 TYR D CG  1 
ATOM 7138 C CD1 . TYR E 5 380 ? 116.441 104.146 137.575 1.00 87.14  ? 274 TYR D CD1 1 
ATOM 7139 C CD2 . TYR E 5 380 ? 116.047 106.249 136.534 1.00 87.48  ? 274 TYR D CD2 1 
ATOM 7140 C CE1 . TYR E 5 380 ? 115.691 103.518 136.603 1.00 88.71  ? 274 TYR D CE1 1 
ATOM 7141 C CE2 . TYR E 5 380 ? 115.296 105.630 135.556 1.00 88.10  ? 274 TYR D CE2 1 
ATOM 7142 C CZ  . TYR E 5 380 ? 115.121 104.264 135.595 1.00 89.71  ? 274 TYR D CZ  1 
ATOM 7143 O OH  . TYR E 5 380 ? 114.373 103.642 134.624 1.00 91.01  ? 274 TYR D OH  1 
ATOM 7144 N N   . VAL E 5 381 ? 118.071 107.692 141.436 1.00 92.39  ? 275 VAL D N   1 
ATOM 7145 C CA  . VAL E 5 381 ? 118.988 107.901 142.553 1.00 92.64  ? 275 VAL D CA  1 
ATOM 7146 C C   . VAL E 5 381 ? 118.332 107.471 143.860 1.00 93.44  ? 275 VAL D C   1 
ATOM 7147 O O   . VAL E 5 381 ? 118.977 106.854 144.717 1.00 94.76  ? 275 VAL D O   1 
ATOM 7148 C CB  . VAL E 5 381 ? 119.474 109.362 142.615 1.00 93.26  ? 275 VAL D CB  1 
ATOM 7149 C CG1 . VAL E 5 381 ? 120.182 109.748 141.322 1.00 94.24  ? 275 VAL D CG1 1 
ATOM 7150 C CG2 . VAL E 5 381 ? 118.331 110.304 142.919 1.00 91.88  ? 275 VAL D CG2 1 
ATOM 7151 N N   . LEU E 5 382 ? 117.042 107.771 144.033 1.00 95.53  ? 276 LEU D N   1 
ATOM 7152 C CA  . LEU E 5 382 ? 116.343 107.340 145.237 1.00 96.28  ? 276 LEU D CA  1 
ATOM 7153 C C   . LEU E 5 382 ? 116.302 105.822 145.334 1.00 96.37  ? 276 LEU D C   1 
ATOM 7154 O O   . LEU E 5 382 ? 116.553 105.256 146.404 1.00 96.51  ? 276 LEU D O   1 
ATOM 7155 C CB  . LEU E 5 382 ? 114.930 107.923 145.250 1.00 96.41  ? 276 LEU D CB  1 
ATOM 7156 C CG  . LEU E 5 382 ? 114.042 107.593 146.451 1.00 95.84  ? 276 LEU D CG  1 
ATOM 7157 C CD1 . LEU E 5 382 ? 113.216 108.808 146.835 1.00 95.17  ? 276 LEU D CD1 1 
ATOM 7158 C CD2 . LEU E 5 382 ? 113.133 106.411 146.148 1.00 95.91  ? 276 LEU D CD2 1 
ATOM 7159 N N   . ASN E 5 383 ? 115.994 105.141 144.227 1.00 97.51  ? 277 ASN D N   1 
ATOM 7160 C CA  . ASN E 5 383 ? 115.964 103.681 144.265 1.00 96.88  ? 277 ASN D CA  1 
ATOM 7161 C C   . ASN E 5 383 ? 117.339 103.106 144.585 1.00 97.66  ? 277 ASN D C   1 
ATOM 7162 O O   . ASN E 5 383 ? 117.459 102.173 145.389 1.00 99.53  ? 277 ASN D O   1 
ATOM 7163 C CB  . ASN E 5 383 ? 115.449 103.128 142.938 1.00 97.68  ? 277 ASN D CB  1 
ATOM 7164 C CG  . ASN E 5 383 ? 113.943 103.206 142.823 1.00 97.79  ? 277 ASN D CG  1 
ATOM 7165 O OD1 . ASN E 5 383 ? 113.308 104.075 143.419 1.00 97.29  ? 277 ASN D OD1 1 
ATOM 7166 N ND2 . ASN E 5 383 ? 113.361 102.292 142.058 1.00 97.86  ? 277 ASN D ND2 1 
ATOM 7167 N N   . ILE E 5 384 ? 118.392 103.652 143.970 1.00 99.04  ? 278 ILE D N   1 
ATOM 7168 C CA  . ILE E 5 384 ? 119.738 103.137 144.206 1.00 99.07  ? 278 ILE D CA  1 
ATOM 7169 C C   . ILE E 5 384 ? 120.137 103.340 145.661 1.00 99.04  ? 278 ILE D C   1 
ATOM 7170 O O   . ILE E 5 384 ? 120.740 102.458 146.284 1.00 98.44  ? 278 ILE D O   1 
ATOM 7171 C CB  . ILE E 5 384 ? 120.739 103.803 143.242 1.00 99.73  ? 278 ILE D CB  1 
ATOM 7172 C CG1 . ILE E 5 384 ? 120.488 103.318 141.809 1.00 99.64  ? 278 ILE D CG1 1 
ATOM 7173 C CG2 . ILE E 5 384 ? 122.174 103.510 143.675 1.00 99.20  ? 278 ILE D CG2 1 
ATOM 7174 C CD1 . ILE E 5 384 ? 121.228 104.103 140.738 1.00 97.30  ? 278 ILE D CD1 1 
ATOM 7175 N N   . VAL E 5 385 ? 119.814 104.505 146.227 1.00 103.70 ? 279 VAL D N   1 
ATOM 7176 C CA  . VAL E 5 385 ? 120.105 104.745 147.637 1.00 104.48 ? 279 VAL D CA  1 
ATOM 7177 C C   . VAL E 5 385 ? 119.329 103.767 148.510 1.00 104.92 ? 279 VAL D C   1 
ATOM 7178 O O   . VAL E 5 385 ? 119.857 103.238 149.497 1.00 105.12 ? 279 VAL D O   1 
ATOM 7179 C CB  . VAL E 5 385 ? 119.791 106.207 148.006 1.00 104.08 ? 279 VAL D CB  1 
ATOM 7180 C CG1 . VAL E 5 385 ? 119.832 106.399 149.515 1.00 104.06 ? 279 VAL D CG1 1 
ATOM 7181 C CG2 . VAL E 5 385 ? 120.769 107.149 147.318 1.00 102.87 ? 279 VAL D CG2 1 
ATOM 7182 N N   . ASN E 5 386 ? 118.066 103.511 148.165 1.00 109.87 ? 280 ASN D N   1 
ATOM 7183 C CA  . ASN E 5 386 ? 117.255 102.596 148.960 1.00 110.23 ? 280 ASN D CA  1 
ATOM 7184 C C   . ASN E 5 386 ? 117.841 101.190 148.957 1.00 109.80 ? 280 ASN D C   1 
ATOM 7185 O O   . ASN E 5 386 ? 117.889 100.527 150.000 1.00 109.80 ? 280 ASN D O   1 
ATOM 7186 C CB  . ASN E 5 386 ? 115.822 102.574 148.429 1.00 109.80 ? 280 ASN D CB  1 
ATOM 7187 C CG  . ASN E 5 386 ? 114.962 101.535 149.117 1.00 109.85 ? 280 ASN D CG  1 
ATOM 7188 O OD1 . ASN E 5 386 ? 114.407 101.782 150.188 1.00 110.35 ? 280 ASN D OD1 1 
ATOM 7189 N ND2 . ASN E 5 386 ? 114.842 100.365 148.502 1.00 109.12 ? 280 ASN D ND2 1 
ATOM 7190 N N   . VAL E 5 387 ? 118.292 100.715 147.793 1.00 108.24 ? 281 VAL D N   1 
ATOM 7191 C CA  . VAL E 5 387 ? 118.808 99.353  147.705 1.00 108.24 ? 281 VAL D CA  1 
ATOM 7192 C C   . VAL E 5 387 ? 120.101 99.179  148.490 1.00 109.51 ? 281 VAL D C   1 
ATOM 7193 O O   . VAL E 5 387 ? 120.437 98.055  148.879 1.00 109.83 ? 281 VAL D O   1 
ATOM 7194 C CB  . VAL E 5 387 ? 119.029 98.955  146.235 1.00 109.33 ? 281 VAL D CB  1 
ATOM 7195 C CG1 . VAL E 5 387 ? 119.689 97.584  146.141 1.00 109.60 ? 281 VAL D CG1 1 
ATOM 7196 C CG2 . VAL E 5 387 ? 117.715 98.962  145.482 1.00 109.24 ? 281 VAL D CG2 1 
ATOM 7197 N N   . VAL E 5 388 ? 120.836 100.258 148.739 1.00 110.86 ? 282 VAL D N   1 
ATOM 7198 C CA  . VAL E 5 388 ? 122.124 100.200 149.417 1.00 110.59 ? 282 VAL D CA  1 
ATOM 7199 C C   . VAL E 5 388 ? 122.003 100.636 150.872 1.00 110.77 ? 282 VAL D C   1 
ATOM 7200 O O   . VAL E 5 388 ? 122.492 99.955  151.775 1.00 110.16 ? 282 VAL D O   1 
ATOM 7201 C CB  . VAL E 5 388 ? 123.176 101.051 148.671 1.00 110.22 ? 282 VAL D CB  1 
ATOM 7202 C CG1 . VAL E 5 388 ? 124.477 101.103 149.459 1.00 110.53 ? 282 VAL D CG1 1 
ATOM 7203 C CG2 . VAL E 5 388 ? 123.412 100.498 147.272 1.00 109.90 ? 282 VAL D CG2 1 
ATOM 7204 N N   . CYS E 5 389 ? 121.350 101.772 151.118 1.00 117.06 ? 283 CYS D N   1 
ATOM 7205 C CA  . CYS E 5 389 ? 121.201 102.308 152.460 1.00 117.79 ? 283 CYS D CA  1 
ATOM 7206 C C   . CYS E 5 389 ? 119.745 102.233 152.912 1.00 117.81 ? 283 CYS D C   1 
ATOM 7207 O O   . CYS E 5 389 ? 118.829 102.289 152.085 1.00 117.66 ? 283 CYS D O   1 
ATOM 7208 C CB  . CYS E 5 389 ? 121.669 103.767 152.524 1.00 117.57 ? 283 CYS D CB  1 
ATOM 7209 S SG  . CYS E 5 389 ? 123.350 104.039 151.912 1.00 117.76 ? 283 CYS D SG  1 
ATOM 7210 N N   . PRO E 5 390 ? 119.494 102.109 154.213 1.00 121.46 ? 284 PRO D N   1 
ATOM 7211 C CA  . PRO E 5 390 ? 118.113 102.142 154.700 1.00 121.88 ? 284 PRO D CA  1 
ATOM 7212 C C   . PRO E 5 390 ? 117.535 103.546 154.621 1.00 121.88 ? 284 PRO D C   1 
ATOM 7213 O O   . PRO E 5 390 ? 118.252 104.540 154.492 1.00 120.72 ? 284 PRO D O   1 
ATOM 7214 C CB  . PRO E 5 390 ? 118.236 101.668 156.152 1.00 121.10 ? 284 PRO D CB  1 
ATOM 7215 C CG  . PRO E 5 390 ? 119.617 102.040 156.548 1.00 120.89 ? 284 PRO D CG  1 
ATOM 7216 C CD  . PRO E 5 390 ? 120.459 101.913 155.309 1.00 120.81 ? 284 PRO D CD  1 
ATOM 7217 N N   . LEU E 5 391 ? 116.209 103.614 154.695 1.00 124.58 ? 285 LEU D N   1 
ATOM 7218 C CA  . LEU E 5 391 ? 115.490 104.875 154.626 1.00 124.22 ? 285 LEU D CA  1 
ATOM 7219 C C   . LEU E 5 391 ? 114.527 104.994 155.798 1.00 124.71 ? 285 LEU D C   1 
ATOM 7220 O O   . LEU E 5 391 ? 114.079 103.979 156.342 1.00 124.32 ? 285 LEU D O   1 
ATOM 7221 C CB  . LEU E 5 391 ? 114.709 104.997 153.309 1.00 124.64 ? 285 LEU D CB  1 
ATOM 7222 C CG  . LEU E 5 391 ? 115.546 105.108 152.032 1.00 124.83 ? 285 LEU D CG  1 
ATOM 7223 C CD1 . LEU E 5 391 ? 114.648 105.056 150.810 1.00 123.85 ? 285 LEU D CD1 1 
ATOM 7224 C CD2 . LEU E 5 391 ? 116.379 106.382 152.030 1.00 124.42 ? 285 LEU D CD2 1 
ATOM 7225 N N   . PRO E 5 392 ? 114.192 106.218 156.212 1.00 130.47 ? 286 PRO D N   1 
ATOM 7226 C CA  . PRO E 5 392 ? 113.266 106.379 157.338 1.00 130.87 ? 286 PRO D CA  1 
ATOM 7227 C C   . PRO E 5 392 ? 111.898 105.787 157.033 1.00 130.53 ? 286 PRO D C   1 
ATOM 7228 O O   . PRO E 5 392 ? 111.455 105.744 155.883 1.00 129.80 ? 286 PRO D O   1 
ATOM 7229 C CB  . PRO E 5 392 ? 113.190 107.899 157.525 1.00 130.52 ? 286 PRO D CB  1 
ATOM 7230 C CG  . PRO E 5 392 ? 114.422 108.429 156.891 1.00 129.91 ? 286 PRO D CG  1 
ATOM 7231 C CD  . PRO E 5 392 ? 114.719 107.514 155.749 1.00 129.81 ? 286 PRO D CD  1 
ATOM 7232 N N   . GLU E 5 393 ? 111.228 105.327 158.090 1.00 133.05 ? 287 GLU D N   1 
ATOM 7233 C CA  . GLU E 5 393 ? 109.940 104.657 157.976 1.00 133.07 ? 287 GLU D CA  1 
ATOM 7234 C C   . GLU E 5 393 ? 108.774 105.499 158.476 1.00 133.32 ? 287 GLU D C   1 
ATOM 7235 O O   . GLU E 5 393 ? 107.634 105.026 158.448 1.00 132.97 ? 287 GLU D O   1 
ATOM 7236 C CB  . GLU E 5 393 ? 109.973 103.330 158.745 1.00 133.10 ? 287 GLU D CB  1 
ATOM 7237 C CG  . GLU E 5 393 ? 110.970 102.317 158.201 1.00 133.05 ? 287 GLU D CG  1 
ATOM 7238 C CD  . GLU E 5 393 ? 112.404 102.641 158.574 1.00 133.57 ? 287 GLU D CD  1 
ATOM 7239 O OE1 . GLU E 5 393 ? 112.620 103.623 159.317 1.00 133.93 ? 287 GLU D OE1 1 
ATOM 7240 O OE2 . GLU E 5 393 ? 113.317 101.918 158.123 1.00 133.53 ? 287 GLU D OE2 1 
ATOM 7241 N N   . GLU E 5 394 ? 109.020 106.725 158.929 1.00 133.27 ? 288 GLU D N   1 
ATOM 7242 C CA  . GLU E 5 394 ? 107.935 107.545 159.448 1.00 132.75 ? 288 GLU D CA  1 
ATOM 7243 C C   . GLU E 5 394 ? 107.024 108.000 158.308 1.00 132.89 ? 288 GLU D C   1 
ATOM 7244 O O   . GLU E 5 394 ? 107.505 108.289 157.207 1.00 132.35 ? 288 GLU D O   1 
ATOM 7245 C CB  . GLU E 5 394 ? 108.478 108.764 160.198 1.00 132.28 ? 288 GLU D CB  1 
ATOM 7246 C CG  . GLU E 5 394 ? 109.522 109.578 159.445 1.00 132.21 ? 288 GLU D CG  1 
ATOM 7247 C CD  . GLU E 5 394 ? 110.940 109.128 159.737 1.00 132.41 ? 288 GLU D CD  1 
ATOM 7248 O OE1 . GLU E 5 394 ? 111.128 107.948 160.101 1.00 132.16 ? 288 GLU D OE1 1 
ATOM 7249 O OE2 . GLU E 5 394 ? 111.867 109.955 159.608 1.00 132.49 ? 288 GLU D OE2 1 
ATOM 7250 N N   . PRO E 5 395 ? 105.708 108.078 158.534 1.00 132.49 ? 289 PRO D N   1 
ATOM 7251 C CA  . PRO E 5 395 ? 104.814 108.540 157.458 1.00 132.11 ? 289 PRO D CA  1 
ATOM 7252 C C   . PRO E 5 395 ? 105.076 109.970 157.017 1.00 131.84 ? 289 PRO D C   1 
ATOM 7253 O O   . PRO E 5 395 ? 104.663 110.345 155.914 1.00 131.71 ? 289 PRO D O   1 
ATOM 7254 C CB  . PRO E 5 395 ? 103.413 108.394 158.071 1.00 132.39 ? 289 PRO D CB  1 
ATOM 7255 C CG  . PRO E 5 395 ? 103.574 107.451 159.204 1.00 132.34 ? 289 PRO D CG  1 
ATOM 7256 C CD  . PRO E 5 395 ? 104.950 107.680 159.733 1.00 131.94 ? 289 PRO D CD  1 
ATOM 7257 N N   . ALA E 5 396 ? 105.735 110.785 157.844 1.00 129.51 ? 290 ALA D N   1 
ATOM 7258 C CA  . ALA E 5 396 ? 105.983 112.171 157.462 1.00 129.61 ? 290 ALA D CA  1 
ATOM 7259 C C   . ALA E 5 396 ? 106.859 112.253 156.219 1.00 128.70 ? 290 ALA D C   1 
ATOM 7260 O O   . ALA E 5 396 ? 106.607 113.071 155.326 1.00 127.52 ? 290 ALA D O   1 
ATOM 7261 C CB  . ALA E 5 396 ? 106.628 112.926 158.624 1.00 129.29 ? 290 ALA D CB  1 
ATOM 7262 N N   . PHE E 5 397 ? 107.891 111.415 156.140 1.00 127.57 ? 291 PHE D N   1 
ATOM 7263 C CA  . PHE E 5 397 ? 108.791 111.408 154.995 1.00 127.47 ? 291 PHE D CA  1 
ATOM 7264 C C   . PHE E 5 397 ? 108.228 110.655 153.797 1.00 127.41 ? 291 PHE D C   1 
ATOM 7265 O O   . PHE E 5 397 ? 108.847 110.679 152.729 1.00 127.32 ? 291 PHE D O   1 
ATOM 7266 C CB  . PHE E 5 397 ? 110.143 110.793 155.387 1.00 127.58 ? 291 PHE D CB  1 
ATOM 7267 C CG  . PHE E 5 397 ? 111.052 111.717 156.173 1.00 128.19 ? 291 PHE D CG  1 
ATOM 7268 C CD1 . PHE E 5 397 ? 110.867 113.094 156.183 1.00 127.81 ? 291 PHE D CD1 1 
ATOM 7269 C CD2 . PHE E 5 397 ? 112.113 111.193 156.893 1.00 127.71 ? 291 PHE D CD2 1 
ATOM 7270 C CE1 . PHE E 5 397 ? 111.714 113.918 156.902 1.00 127.44 ? 291 PHE D CE1 1 
ATOM 7271 C CE2 . PHE E 5 397 ? 112.961 112.014 157.613 1.00 127.60 ? 291 PHE D CE2 1 
ATOM 7272 C CZ  . PHE E 5 397 ? 112.760 113.377 157.615 1.00 127.43 ? 291 PHE D CZ  1 
ATOM 7273 N N   . PHE E 5 398 ? 107.077 109.996 153.937 1.00 123.04 ? 292 PHE D N   1 
ATOM 7274 C CA  . PHE E 5 398 ? 106.458 109.328 152.798 1.00 122.11 ? 292 PHE D CA  1 
ATOM 7275 C C   . PHE E 5 398 ? 105.976 110.305 151.734 1.00 121.73 ? 292 PHE D C   1 
ATOM 7276 O O   . PHE E 5 398 ? 105.666 109.873 150.619 1.00 121.66 ? 292 PHE D O   1 
ATOM 7277 C CB  . PHE E 5 398 ? 105.282 108.471 153.269 1.00 122.40 ? 292 PHE D CB  1 
ATOM 7278 C CG  . PHE E 5 398 ? 105.655 107.056 153.596 1.00 123.59 ? 292 PHE D CG  1 
ATOM 7279 C CD1 . PHE E 5 398 ? 106.748 106.777 154.400 1.00 122.96 ? 292 PHE D CD1 1 
ATOM 7280 C CD2 . PHE E 5 398 ? 104.902 106.001 153.109 1.00 122.80 ? 292 PHE D CD2 1 
ATOM 7281 C CE1 . PHE E 5 398 ? 107.086 105.472 154.702 1.00 122.27 ? 292 PHE D CE1 1 
ATOM 7282 C CE2 . PHE E 5 398 ? 105.238 104.700 153.408 1.00 122.70 ? 292 PHE D CE2 1 
ATOM 7283 C CZ  . PHE E 5 398 ? 106.328 104.435 154.206 1.00 122.52 ? 292 PHE D CZ  1 
ATOM 7284 N N   . GLY E 5 399 ? 105.905 111.599 152.046 1.00 118.59 ? 293 GLY D N   1 
ATOM 7285 C CA  . GLY E 5 399 ? 105.404 112.557 151.075 1.00 117.93 ? 293 GLY D CA  1 
ATOM 7286 C C   . GLY E 5 399 ? 106.305 112.703 149.863 1.00 117.96 ? 293 GLY D C   1 
ATOM 7287 O O   . GLY E 5 399 ? 105.825 112.750 148.727 1.00 118.10 ? 293 GLY D O   1 
ATOM 7288 N N   . LEU E 5 400 ? 107.620 112.775 150.082 1.00 114.32 ? 294 LEU D N   1 
ATOM 7289 C CA  . LEU E 5 400 ? 108.532 113.050 148.975 1.00 114.13 ? 294 LEU D CA  1 
ATOM 7290 C C   . LEU E 5 400 ? 108.626 111.876 148.009 1.00 114.51 ? 294 LEU D C   1 
ATOM 7291 O O   . LEU E 5 400 ? 108.891 112.078 146.818 1.00 114.35 ? 294 LEU D O   1 
ATOM 7292 C CB  . LEU E 5 400 ? 109.919 113.416 149.512 1.00 114.12 ? 294 LEU D CB  1 
ATOM 7293 C CG  . LEU E 5 400 ? 110.666 112.404 150.390 1.00 113.90 ? 294 LEU D CG  1 
ATOM 7294 C CD1 . LEU E 5 400 ? 111.475 111.414 149.561 1.00 113.18 ? 294 LEU D CD1 1 
ATOM 7295 C CD2 . LEU E 5 400 ? 111.571 113.135 151.373 1.00 113.56 ? 294 LEU D CD2 1 
ATOM 7296 N N   . TYR E 5 401 ? 108.424 110.651 148.496 1.00 113.41 ? 295 TYR D N   1 
ATOM 7297 C CA  . TYR E 5 401 ? 108.539 109.487 147.624 1.00 113.45 ? 295 TYR D CA  1 
ATOM 7298 C C   . TYR E 5 401 ? 107.492 109.522 146.520 1.00 114.26 ? 295 TYR D C   1 
ATOM 7299 O O   . TYR E 5 401 ? 107.785 109.196 145.363 1.00 114.08 ? 295 TYR D O   1 
ATOM 7300 C CB  . TYR E 5 401 ? 108.414 108.206 148.445 1.00 113.05 ? 295 TYR D CB  1 
ATOM 7301 C CG  . TYR E 5 401 ? 109.524 108.020 149.449 1.00 113.77 ? 295 TYR D CG  1 
ATOM 7302 C CD1 . TYR E 5 401 ? 110.690 107.353 149.106 1.00 114.16 ? 295 TYR D CD1 1 
ATOM 7303 C CD2 . TYR E 5 401 ? 109.407 108.512 150.740 1.00 114.47 ? 295 TYR D CD2 1 
ATOM 7304 C CE1 . TYR E 5 401 ? 111.710 107.179 150.022 1.00 114.50 ? 295 TYR D CE1 1 
ATOM 7305 C CE2 . TYR E 5 401 ? 110.419 108.342 151.665 1.00 114.22 ? 295 TYR D CE2 1 
ATOM 7306 C CZ  . TYR E 5 401 ? 111.568 107.676 151.300 1.00 114.32 ? 295 TYR D CZ  1 
ATOM 7307 O OH  . TYR E 5 401 ? 112.580 107.506 152.216 1.00 113.85 ? 295 TYR D OH  1 
ATOM 7308 N N   . PHE E 5 402 ? 106.265 109.918 146.855 1.00 112.22 ? 296 PHE D N   1 
ATOM 7309 C CA  . PHE E 5 402 ? 105.208 109.979 145.851 1.00 110.51 ? 296 PHE D CA  1 
ATOM 7310 C C   . PHE E 5 402 ? 105.499 111.052 144.807 1.00 111.16 ? 296 PHE D C   1 
ATOM 7311 O O   . PHE E 5 402 ? 105.257 110.846 143.613 1.00 112.14 ? 296 PHE D O   1 
ATOM 7312 C CB  . PHE E 5 402 ? 103.866 110.226 146.534 1.00 110.92 ? 296 PHE D CB  1 
ATOM 7313 C CG  . PHE E 5 402 ? 103.594 109.299 147.684 1.00 112.25 ? 296 PHE D CG  1 
ATOM 7314 C CD1 . PHE E 5 402 ? 104.025 107.982 147.648 1.00 112.47 ? 296 PHE D CD1 1 
ATOM 7315 C CD2 . PHE E 5 402 ? 102.920 109.746 148.809 1.00 112.61 ? 296 PHE D CD2 1 
ATOM 7316 C CE1 . PHE E 5 402 ? 103.782 107.127 148.707 1.00 112.76 ? 296 PHE D CE1 1 
ATOM 7317 C CE2 . PHE E 5 402 ? 102.674 108.895 149.872 1.00 112.88 ? 296 PHE D CE2 1 
ATOM 7318 C CZ  . PHE E 5 402 ? 103.106 107.584 149.819 1.00 113.29 ? 296 PHE D CZ  1 
ATOM 7319 N N   . LEU E 5 403 ? 106.024 112.202 145.234 1.00 104.28 ? 297 LEU D N   1 
ATOM 7320 C CA  . LEU E 5 403 ? 106.411 113.241 144.284 1.00 104.50 ? 297 LEU D CA  1 
ATOM 7321 C C   . LEU E 5 403 ? 107.516 112.750 143.354 1.00 104.11 ? 297 LEU D C   1 
ATOM 7322 O O   . LEU E 5 403 ? 107.479 112.992 142.136 1.00 105.33 ? 297 LEU D O   1 
ATOM 7323 C CB  . LEU E 5 403 ? 106.859 114.486 145.052 1.00 104.06 ? 297 LEU D CB  1 
ATOM 7324 C CG  . LEU E 5 403 ? 106.915 115.827 144.318 1.00 105.24 ? 297 LEU D CG  1 
ATOM 7325 C CD1 . LEU E 5 403 ? 106.752 116.966 145.316 1.00 104.52 ? 297 LEU D CD1 1 
ATOM 7326 C CD2 . LEU E 5 403 ? 108.215 115.986 143.542 1.00 104.76 ? 297 LEU D CD2 1 
ATOM 7327 N N   . VAL E 5 404 ? 108.511 112.060 143.914 1.00 96.11  ? 298 VAL D N   1 
ATOM 7328 C CA  . VAL E 5 404 ? 109.590 111.518 143.098 1.00 95.04  ? 298 VAL D CA  1 
ATOM 7329 C C   . VAL E 5 404 ? 109.034 110.528 142.084 1.00 95.10  ? 298 VAL D C   1 
ATOM 7330 O O   . VAL E 5 404 ? 109.438 110.518 140.916 1.00 97.32  ? 298 VAL D O   1 
ATOM 7331 C CB  . VAL E 5 404 ? 110.661 110.872 143.997 1.00 95.79  ? 298 VAL D CB  1 
ATOM 7332 C CG1 . VAL E 5 404 ? 111.657 110.083 143.167 1.00 96.15  ? 298 VAL D CG1 1 
ATOM 7333 C CG2 . VAL E 5 404 ? 111.373 111.936 144.816 1.00 95.33  ? 298 VAL D CG2 1 
ATOM 7334 N N   . VAL E 5 405 ? 108.097 109.683 142.514 1.00 94.96  ? 299 VAL D N   1 
ATOM 7335 C CA  . VAL E 5 405 ? 107.504 108.711 141.603 1.00 96.19  ? 299 VAL D CA  1 
ATOM 7336 C C   . VAL E 5 405 ? 106.674 109.404 140.528 1.00 96.52  ? 299 VAL D C   1 
ATOM 7337 O O   . VAL E 5 405 ? 106.566 108.903 139.402 1.00 97.82  ? 299 VAL D O   1 
ATOM 7338 C CB  . VAL E 5 405 ? 106.665 107.691 142.394 1.00 95.92  ? 299 VAL D CB  1 
ATOM 7339 C CG1 . VAL E 5 405 ? 105.834 106.838 141.453 1.00 96.21  ? 299 VAL D CG1 1 
ATOM 7340 C CG2 . VAL E 5 405 ? 107.566 106.817 143.252 1.00 95.21  ? 299 VAL D CG2 1 
ATOM 7341 N N   . ALA E 5 406 ? 106.059 110.543 140.851 1.00 89.01  ? 300 ALA D N   1 
ATOM 7342 C CA  . ALA E 5 406 ? 105.192 111.229 139.900 1.00 88.86  ? 300 ALA D CA  1 
ATOM 7343 C C   . ALA E 5 406 ? 105.953 112.080 138.888 1.00 88.29  ? 300 ALA D C   1 
ATOM 7344 O O   . ALA E 5 406 ? 105.402 112.387 137.826 1.00 86.79  ? 300 ALA D O   1 
ATOM 7345 C CB  . ALA E 5 406 ? 104.191 112.113 140.647 1.00 87.92  ? 300 ALA D CB  1 
ATOM 7346 N N   . LEU E 5 407 ? 107.192 112.475 139.187 1.00 86.52  ? 301 LEU D N   1 
ATOM 7347 C CA  . LEU E 5 407 ? 107.926 113.335 138.255 1.00 85.85  ? 301 LEU D CA  1 
ATOM 7348 C C   . LEU E 5 407 ? 108.038 112.752 136.847 1.00 89.01  ? 301 LEU D C   1 
ATOM 7349 O O   . LEU E 5 407 ? 107.778 113.486 135.872 1.00 90.03  ? 301 LEU D O   1 
ATOM 7350 C CB  . LEU E 5 407 ? 109.314 113.640 138.828 1.00 84.63  ? 301 LEU D CB  1 
ATOM 7351 C CG  . LEU E 5 407 ? 109.415 114.789 139.833 1.00 86.69  ? 301 LEU D CG  1 
ATOM 7352 C CD1 . LEU E 5 407 ? 110.802 114.815 140.452 1.00 87.02  ? 301 LEU D CD1 1 
ATOM 7353 C CD2 . LEU E 5 407 ? 109.101 116.126 139.180 1.00 86.51  ? 301 LEU D CD2 1 
ATOM 7354 N N   . PRO E 5 408 ? 108.425 111.487 136.654 1.00 81.39  ? 302 PRO D N   1 
ATOM 7355 C CA  . PRO E 5 408 ? 108.510 110.959 135.282 1.00 79.42  ? 302 PRO D CA  1 
ATOM 7356 C C   . PRO E 5 408 ? 107.205 111.064 134.516 1.00 80.70  ? 302 PRO D C   1 
ATOM 7357 O O   . PRO E 5 408 ? 107.217 111.256 133.293 1.00 82.37  ? 302 PRO D O   1 
ATOM 7358 C CB  . PRO E 5 408 ? 108.920 109.498 135.498 1.00 80.05  ? 302 PRO D CB  1 
ATOM 7359 C CG  . PRO E 5 408 ? 109.611 109.488 136.798 1.00 79.69  ? 302 PRO D CG  1 
ATOM 7360 C CD  . PRO E 5 408 ? 108.941 110.526 137.642 1.00 79.10  ? 302 PRO D CD  1 
ATOM 7361 N N   . TYR E 5 409 ? 106.070 110.936 135.200 1.00 82.84  ? 303 TYR D N   1 
ATOM 7362 C CA  . TYR E 5 409 ? 104.790 111.128 134.533 1.00 80.22  ? 303 TYR D CA  1 
ATOM 7363 C C   . TYR E 5 409 ? 104.615 112.572 134.082 1.00 82.45  ? 303 TYR D C   1 
ATOM 7364 O O   . TYR E 5 409 ? 104.021 112.824 133.028 1.00 84.54  ? 303 TYR D O   1 
ATOM 7365 C CB  . TYR E 5 409 ? 103.660 110.700 135.463 1.00 82.87  ? 303 TYR D CB  1 
ATOM 7366 C CG  . TYR E 5 409 ? 103.762 109.250 135.878 1.00 84.65  ? 303 TYR D CG  1 
ATOM 7367 C CD1 . TYR E 5 409 ? 103.222 108.244 135.092 1.00 85.11  ? 303 TYR D CD1 1 
ATOM 7368 C CD2 . TYR E 5 409 ? 104.407 108.889 137.053 1.00 83.30  ? 303 TYR D CD2 1 
ATOM 7369 C CE1 . TYR E 5 409 ? 103.316 106.918 135.468 1.00 85.07  ? 303 TYR D CE1 1 
ATOM 7370 C CE2 . TYR E 5 409 ? 104.505 107.567 137.436 1.00 81.74  ? 303 TYR D CE2 1 
ATOM 7371 C CZ  . TYR E 5 409 ? 103.959 106.586 136.639 1.00 83.51  ? 303 TYR D CZ  1 
ATOM 7372 O OH  . TYR E 5 409 ? 104.053 105.268 137.015 1.00 83.18  ? 303 TYR D OH  1 
ATOM 7373 N N   . ALA E 5 410 ? 105.140 113.531 134.848 1.00 77.69  ? 304 ALA D N   1 
ATOM 7374 C CA  . ALA E 5 410 ? 105.153 114.914 134.384 1.00 77.83  ? 304 ALA D CA  1 
ATOM 7375 C C   . ALA E 5 410 ? 105.995 115.058 133.124 1.00 75.05  ? 304 ALA D C   1 
ATOM 7376 O O   . ALA E 5 410 ? 105.628 115.797 132.202 1.00 76.07  ? 304 ALA D O   1 
ATOM 7377 C CB  . ALA E 5 410 ? 105.674 115.835 135.486 1.00 78.57  ? 304 ALA D CB  1 
ATOM 7378 N N   . ASN E 5 411 ? 107.134 114.363 133.062 1.00 70.18  ? 305 ASN D N   1 
ATOM 7379 C CA  . ASN E 5 411 ? 107.933 114.399 131.837 1.00 70.43  ? 305 ASN D CA  1 
ATOM 7380 C C   . ASN E 5 411 ? 107.157 113.835 130.653 1.00 68.20  ? 305 ASN D C   1 
ATOM 7381 O O   . ASN E 5 411 ? 107.213 114.379 129.543 1.00 73.78  ? 305 ASN D O   1 
ATOM 7382 C CB  . ASN E 5 411 ? 109.229 113.617 132.025 1.00 72.46  ? 305 ASN D CB  1 
ATOM 7383 C CG  . ASN E 5 411 ? 110.136 113.694 130.813 1.00 71.92  ? 305 ASN D CG  1 
ATOM 7384 O OD1 . ASN E 5 411 ? 109.979 114.566 129.960 1.00 70.74  ? 305 ASN D OD1 1 
ATOM 7385 N ND2 . ASN E 5 411 ? 111.091 112.782 130.734 1.00 73.24  ? 305 ASN D ND2 1 
ATOM 7386 N N   . SER E 5 412 ? 106.455 112.723 130.865 1.00 71.27  ? 306 SER D N   1 
ATOM 7387 C CA  . SER E 5 412 ? 105.651 112.148 129.791 1.00 73.61  ? 306 SER D CA  1 
ATOM 7388 C C   . SER E 5 412 ? 104.540 113.097 129.362 1.00 71.91  ? 306 SER D C   1 
ATOM 7389 O O   . SER E 5 412 ? 104.186 113.147 128.179 1.00 72.02  ? 306 SER D O   1 
ATOM 7390 C CB  . SER E 5 412 ? 105.067 110.809 130.236 1.00 76.87  ? 306 SER D CB  1 
ATOM 7391 O OG  . SER E 5 412 ? 106.096 109.882 130.526 1.00 74.45  ? 306 SER D OG  1 
ATOM 7392 N N   . CYS E 5 413 ? 103.972 113.848 130.308 1.00 75.52  ? 307 CYS D N   1 
ATOM 7393 C CA  . CYS E 5 413 ? 102.995 114.874 129.956 1.00 79.09  ? 307 CYS D CA  1 
ATOM 7394 C C   . CYS E 5 413 ? 103.627 115.969 129.107 1.00 77.16  ? 307 CYS D C   1 
ATOM 7395 O O   . CYS E 5 413 ? 103.008 116.465 128.159 1.00 74.99  ? 307 CYS D O   1 
ATOM 7396 C CB  . CYS E 5 413 ? 102.393 115.484 131.221 1.00 78.24  ? 307 CYS D CB  1 
ATOM 7397 S SG  . CYS E 5 413 ? 101.559 114.313 132.305 1.00 78.68  ? 307 CYS D SG  1 
ATOM 7398 N N   . ALA E 5 414 ? 104.848 116.376 129.451 1.00 72.23  ? 308 ALA D N   1 
ATOM 7399 C CA  . ALA E 5 414 ? 105.489 117.501 128.781 1.00 69.25  ? 308 ALA D CA  1 
ATOM 7400 C C   . ALA E 5 414 ? 106.071 117.144 127.420 1.00 69.25  ? 308 ALA D C   1 
ATOM 7401 O O   . ALA E 5 414 ? 106.299 118.048 126.611 1.00 72.08  ? 308 ALA D O   1 
ATOM 7402 C CB  . ALA E 5 414 ? 106.598 118.070 129.666 1.00 70.49  ? 308 ALA D CB  1 
ATOM 7403 N N   . ASN E 5 415 ? 106.327 115.865 127.151 1.00 69.02  ? 309 ASN D N   1 
ATOM 7404 C CA  . ASN E 5 415 ? 106.969 115.505 125.886 1.00 71.49  ? 309 ASN D CA  1 
ATOM 7405 C C   . ASN E 5 415 ? 106.199 115.991 124.666 1.00 73.16  ? 309 ASN D C   1 
ATOM 7406 O O   . ASN E 5 415 ? 106.807 116.649 123.802 1.00 74.82  ? 309 ASN D O   1 
ATOM 7407 C CB  . ASN E 5 415 ? 107.170 113.988 125.816 1.00 70.65  ? 309 ASN D CB  1 
ATOM 7408 C CG  . ASN E 5 415 ? 108.582 113.563 126.167 1.00 72.06  ? 309 ASN D CG  1 
ATOM 7409 O OD1 . ASN E 5 415 ? 109.530 114.337 126.040 1.00 74.33  ? 309 ASN D OD1 1 
ATOM 7410 N ND2 . ASN E 5 415 ? 108.729 112.318 126.600 1.00 70.43  ? 309 ASN D ND2 1 
ATOM 7411 N N   . PRO E 5 416 ? 104.900 115.713 124.518 1.00 75.31  ? 310 PRO D N   1 
ATOM 7412 C CA  . PRO E 5 416 ? 104.208 116.135 123.288 1.00 74.45  ? 310 PRO D CA  1 
ATOM 7413 C C   . PRO E 5 416 ? 104.241 117.633 123.057 1.00 72.41  ? 310 PRO D C   1 
ATOM 7414 O O   . PRO E 5 416 ? 104.511 118.067 121.932 1.00 72.92  ? 310 PRO D O   1 
ATOM 7415 C CB  . PRO E 5 416 ? 102.774 115.630 123.503 1.00 74.31  ? 310 PRO D CB  1 
ATOM 7416 C CG  . PRO E 5 416 ? 102.885 114.561 124.515 1.00 77.12  ? 310 PRO D CG  1 
ATOM 7417 C CD  . PRO E 5 416 ? 104.020 114.943 125.407 1.00 73.47  ? 310 PRO D CD  1 
ATOM 7418 N N   . ILE E 5 417 ? 104.032 118.431 124.107 1.00 73.10  ? 311 ILE D N   1 
ATOM 7419 C CA  . ILE E 5 417 ? 103.908 119.876 123.960 1.00 73.96  ? 311 ILE D CA  1 
ATOM 7420 C C   . ILE E 5 417 ? 105.117 120.490 123.272 1.00 70.00  ? 311 ILE D C   1 
ATOM 7421 O O   . ILE E 5 417 ? 105.037 121.623 122.786 1.00 69.78  ? 311 ILE D O   1 
ATOM 7422 C CB  . ILE E 5 417 ? 103.668 120.521 125.344 1.00 75.76  ? 311 ILE D CB  1 
ATOM 7423 C CG1 . ILE E 5 417 ? 102.291 120.111 125.879 1.00 72.68  ? 311 ILE D CG1 1 
ATOM 7424 C CG2 . ILE E 5 417 ? 103.792 122.041 125.262 1.00 74.47  ? 311 ILE D CG2 1 
ATOM 7425 C CD1 . ILE E 5 417 ? 102.055 120.457 127.337 1.00 72.57  ? 311 ILE D CD1 1 
ATOM 7426 N N   . LEU E 5 418 ? 106.243 119.779 123.217 1.00 68.34  ? 312 LEU D N   1 
ATOM 7427 C CA  . LEU E 5 418 ? 107.393 120.227 122.444 1.00 71.11  ? 312 LEU D CA  1 
ATOM 7428 C C   . LEU E 5 418 ? 107.642 119.365 121.217 1.00 71.05  ? 312 LEU D C   1 
ATOM 7429 O O   . LEU E 5 418 ? 107.781 119.905 120.117 1.00 73.30  ? 312 LEU D O   1 
ATOM 7430 C CB  . LEU E 5 418 ? 108.652 120.279 123.328 1.00 70.39  ? 312 LEU D CB  1 
ATOM 7431 C CG  . LEU E 5 418 ? 109.320 118.995 123.815 1.00 67.44  ? 312 LEU D CG  1 
ATOM 7432 C CD1 . LEU E 5 418 ? 110.405 118.542 122.856 1.00 67.61  ? 312 LEU D CD1 1 
ATOM 7433 C CD2 . LEU E 5 418 ? 109.900 119.218 125.200 1.00 69.04  ? 312 LEU D CD2 1 
ATOM 7434 N N   . TYR E 5 419 ? 107.636 118.037 121.354 1.00 69.44  ? 313 TYR D N   1 
ATOM 7435 C CA  . TYR E 5 419 ? 107.975 117.191 120.213 1.00 69.31  ? 313 TYR D CA  1 
ATOM 7436 C C   . TYR E 5 419 ? 106.998 117.387 119.059 1.00 70.55  ? 313 TYR D C   1 
ATOM 7437 O O   . TYR E 5 419 ? 107.414 117.456 117.897 1.00 73.02  ? 313 TYR D O   1 
ATOM 7438 C CB  . TYR E 5 419 ? 108.025 115.722 120.635 1.00 70.47  ? 313 TYR D CB  1 
ATOM 7439 C CG  . TYR E 5 419 ? 109.386 115.279 121.127 1.00 70.77  ? 313 TYR D CG  1 
ATOM 7440 C CD1 . TYR E 5 419 ? 110.446 115.124 120.246 1.00 71.10  ? 313 TYR D CD1 1 
ATOM 7441 C CD2 . TYR E 5 419 ? 109.611 115.014 122.471 1.00 69.27  ? 313 TYR D CD2 1 
ATOM 7442 C CE1 . TYR E 5 419 ? 111.690 114.723 120.689 1.00 71.46  ? 313 TYR D CE1 1 
ATOM 7443 C CE2 . TYR E 5 419 ? 110.853 114.611 122.921 1.00 68.89  ? 313 TYR D CE2 1 
ATOM 7444 C CZ  . TYR E 5 419 ? 111.887 114.468 122.027 1.00 69.84  ? 313 TYR D CZ  1 
ATOM 7445 O OH  . TYR E 5 419 ? 113.125 114.067 122.472 1.00 69.05  ? 313 TYR D OH  1 
ATOM 7446 N N   . GLY E 5 420 ? 105.699 117.478 119.348 1.00 74.24  ? 314 GLY D N   1 
ATOM 7447 C CA  . GLY E 5 420 ? 104.687 117.596 118.317 1.00 73.14  ? 314 GLY D CA  1 
ATOM 7448 C C   . GLY E 5 420 ? 104.020 118.947 118.195 1.00 73.16  ? 314 GLY D C   1 
ATOM 7449 O O   . GLY E 5 420 ? 103.027 119.062 117.463 1.00 73.66  ? 314 GLY D O   1 
ATOM 7450 N N   . PHE E 5 421 ? 104.507 119.975 118.889 1.00 77.72  ? 315 PHE D N   1 
ATOM 7451 C CA  . PHE E 5 421 ? 103.952 121.317 118.759 1.00 77.97  ? 315 PHE D CA  1 
ATOM 7452 C C   . PHE E 5 421 ? 105.053 122.321 118.460 1.00 77.75  ? 315 PHE D C   1 
ATOM 7453 O O   . PHE E 5 421 ? 104.838 123.273 117.704 1.00 80.78  ? 315 PHE D O   1 
ATOM 7454 C CB  . PHE E 5 421 ? 103.201 121.730 120.029 1.00 79.40  ? 315 PHE D CB  1 
ATOM 7455 C CG  . PHE E 5 421 ? 101.815 121.144 120.155 1.00 80.20  ? 315 PHE D CG  1 
ATOM 7456 C CD1 . PHE E 5 421 ? 101.058 120.825 119.038 1.00 80.32  ? 315 PHE D CD1 1 
ATOM 7457 C CD2 . PHE E 5 421 ? 101.266 120.928 121.407 1.00 79.79  ? 315 PHE D CD2 1 
ATOM 7458 C CE1 . PHE E 5 421 ? 99.792  120.296 119.170 1.00 80.82  ? 315 PHE D CE1 1 
ATOM 7459 C CE2 . PHE E 5 421 ? 99.999  120.398 121.542 1.00 78.91  ? 315 PHE D CE2 1 
ATOM 7460 C CZ  . PHE E 5 421 ? 99.263  120.082 120.422 1.00 80.07  ? 315 PHE D CZ  1 
ATOM 7461 N N   . LEU E 5 422 ? 106.231 122.130 119.043 1.00 77.33  ? 316 LEU D N   1 
ATOM 7462 C CA  . LEU E 5 422 ? 107.388 122.943 118.685 1.00 79.50  ? 316 LEU D CA  1 
ATOM 7463 C C   . LEU E 5 422 ? 108.129 122.314 117.513 1.00 81.26  ? 316 LEU D C   1 
ATOM 7464 O O   . LEU E 5 422 ? 109.330 122.055 117.562 1.00 81.49  ? 316 LEU D O   1 
ATOM 7465 C CB  . LEU E 5 422 ? 108.299 123.125 119.894 1.00 78.65  ? 316 LEU D CB  1 
ATOM 7466 C CG  . LEU E 5 422 ? 107.971 124.333 120.773 1.00 80.31  ? 316 LEU D CG  1 
ATOM 7467 C CD1 . LEU E 5 422 ? 106.542 124.269 121.289 1.00 79.20  ? 316 LEU D CD1 1 
ATOM 7468 C CD2 . LEU E 5 422 ? 108.957 124.435 121.924 1.00 79.67  ? 316 LEU D CD2 1 
ATOM 7469 N N   . SER E 5 423 ? 107.390 122.056 116.436 1.00 85.32  ? 317 SER D N   1 
ATOM 7470 C CA  . SER E 5 423 ? 107.944 121.549 115.190 1.00 85.33  ? 317 SER D CA  1 
ATOM 7471 C C   . SER E 5 423 ? 107.379 122.364 114.037 1.00 86.39  ? 317 SER D C   1 
ATOM 7472 O O   . SER E 5 423 ? 106.195 122.715 114.038 1.00 87.44  ? 317 SER D O   1 
ATOM 7473 C CB  . SER E 5 423 ? 107.623 120.062 115.005 1.00 83.82  ? 317 SER D CB  1 
ATOM 7474 O OG  . SER E 5 423 ? 106.230 119.831 115.067 1.00 84.14  ? 317 SER D OG  1 
ATOM 7475 N N   . TYR E 5 424 ? 108.229 122.664 113.052 1.00 89.90  ? 318 TYR D N   1 
ATOM 7476 C CA  . TYR E 5 424 ? 107.811 123.533 111.957 1.00 90.67  ? 318 TYR D CA  1 
ATOM 7477 C C   . TYR E 5 424 ? 106.689 122.907 111.140 1.00 91.10  ? 318 TYR D C   1 
ATOM 7478 O O   . TYR E 5 424 ? 105.761 123.605 110.716 1.00 91.79  ? 318 TYR D O   1 
ATOM 7479 C CB  . TYR E 5 424 ? 109.001 123.846 111.059 1.00 90.65  ? 318 TYR D CB  1 
ATOM 7480 C CG  . TYR E 5 424 ? 108.713 124.868 109.984 1.00 90.72  ? 318 TYR D CG  1 
ATOM 7481 C CD1 . TYR E 5 424 ? 108.603 126.217 110.291 1.00 90.38  ? 318 TYR D CD1 1 
ATOM 7482 C CD2 . TYR E 5 424 ? 108.565 124.482 108.659 1.00 90.02  ? 318 TYR D CD2 1 
ATOM 7483 C CE1 . TYR E 5 424 ? 108.345 127.152 109.308 1.00 90.58  ? 318 TYR D CE1 1 
ATOM 7484 C CE2 . TYR E 5 424 ? 108.308 125.407 107.672 1.00 90.96  ? 318 TYR D CE2 1 
ATOM 7485 C CZ  . TYR E 5 424 ? 108.199 126.740 108.000 1.00 91.87  ? 318 TYR D CZ  1 
ATOM 7486 O OH  . TYR E 5 424 ? 107.943 127.660 107.011 1.00 91.37  ? 318 TYR D OH  1 
ATOM 7487 N N   . ARG E 5 425 ? 106.749 121.594 110.915 1.00 89.22  ? 319 ARG D N   1 
ATOM 7488 C CA  . ARG E 5 425 ? 105.774 120.950 110.043 1.00 89.68  ? 319 ARG D CA  1 
ATOM 7489 C C   . ARG E 5 425 ? 104.353 121.080 110.575 1.00 90.56  ? 319 ARG D C   1 
ATOM 7490 O O   . ARG E 5 425 ? 103.400 120.874 109.817 1.00 91.88  ? 319 ARG D O   1 
ATOM 7491 C CB  . ARG E 5 425 ? 106.136 119.474 109.858 1.00 90.98  ? 319 ARG D CB  1 
ATOM 7492 C CG  . ARG E 5 425 ? 105.450 118.805 108.673 1.00 92.23  ? 319 ARG D CG  1 
ATOM 7493 C CD  . ARG E 5 425 ? 105.937 117.374 108.471 1.00 91.27  ? 319 ARG D CD  1 
ATOM 7494 N NE  . ARG E 5 425 ? 107.342 117.317 108.086 1.00 90.16  ? 319 ARG D NE  1 
ATOM 7495 C CZ  . ARG E 5 425 ? 108.063 116.205 108.031 1.00 90.65  ? 319 ARG D CZ  1 
ATOM 7496 N NH1 . ARG E 5 425 ? 107.549 115.029 108.349 1.00 90.72  ? 319 ARG D NH1 1 
ATOM 7497 N NH2 . ARG E 5 425 ? 109.335 116.276 107.650 1.00 90.44  ? 319 ARG D NH2 1 
ATOM 7498 N N   . PHE E 5 426 ? 104.189 121.415 111.855 1.00 90.17  ? 320 PHE D N   1 
ATOM 7499 C CA  . PHE E 5 426 ? 102.878 121.630 112.458 1.00 89.22  ? 320 PHE D CA  1 
ATOM 7500 C C   . PHE E 5 426 ? 102.514 123.102 112.576 1.00 90.15  ? 320 PHE D C   1 
ATOM 7501 O O   . PHE E 5 426 ? 101.355 123.465 112.360 1.00 91.09  ? 320 PHE D O   1 
ATOM 7502 C CB  . PHE E 5 426 ? 102.826 120.988 113.846 1.00 89.14  ? 320 PHE D CB  1 
ATOM 7503 C CG  . PHE E 5 426 ? 102.802 119.492 113.818 1.00 89.99  ? 320 PHE D CG  1 
ATOM 7504 C CD1 . PHE E 5 426 ? 103.957 118.774 113.561 1.00 88.84  ? 320 PHE D CD1 1 
ATOM 7505 C CD2 . PHE E 5 426 ? 101.627 118.801 114.050 1.00 89.60  ? 320 PHE D CD2 1 
ATOM 7506 C CE1 . PHE E 5 426 ? 103.942 117.398 113.536 1.00 88.35  ? 320 PHE D CE1 1 
ATOM 7507 C CE2 . PHE E 5 426 ? 101.606 117.423 114.025 1.00 90.77  ? 320 PHE D CE2 1 
ATOM 7508 C CZ  . PHE E 5 426 ? 102.766 116.723 113.767 1.00 90.81  ? 320 PHE D CZ  1 
ATOM 7509 N N   . LYS E 5 427 ? 103.472 123.961 112.921 1.00 92.15  ? 321 LYS D N   1 
ATOM 7510 C CA  . LYS E 5 427 ? 103.188 125.391 112.973 1.00 91.67  ? 321 LYS D CA  1 
ATOM 7511 C C   . LYS E 5 427 ? 102.891 125.937 111.582 1.00 94.18  ? 321 LYS D C   1 
ATOM 7512 O O   . LYS E 5 427 ? 101.908 126.660 111.385 1.00 94.38  ? 321 LYS D O   1 
ATOM 7513 C CB  . LYS E 5 427 ? 104.360 126.138 113.606 1.00 91.72  ? 321 LYS D CB  1 
ATOM 7514 C CG  . LYS E 5 427 ? 104.618 125.765 115.056 1.00 91.39  ? 321 LYS D CG  1 
ATOM 7515 C CD  . LYS E 5 427 ? 105.595 126.721 115.732 1.00 91.49  ? 321 LYS D CD  1 
ATOM 7516 C CE  . LYS E 5 427 ? 106.926 126.797 115.000 1.00 92.08  ? 321 LYS D CE  1 
ATOM 7517 N NZ  . LYS E 5 427 ? 107.508 125.454 114.734 1.00 90.96  ? 321 LYS D NZ  1 
ATOM 7518 N N   . GLN E 5 428 ? 103.731 125.599 110.600 1.00 98.73  ? 322 GLN D N   1 
ATOM 7519 C CA  . GLN E 5 428 ? 103.507 126.070 109.239 1.00 97.74  ? 322 GLN D CA  1 
ATOM 7520 C C   . GLN E 5 428 ? 102.492 125.206 108.497 1.00 96.89  ? 322 GLN D C   1 
ATOM 7521 O O   . GLN E 5 428 ? 101.843 125.688 107.562 1.00 97.31  ? 322 GLN D O   1 
ATOM 7522 C CB  . GLN E 5 428 ? 104.830 126.116 108.473 1.00 95.63  ? 322 GLN D CB  1 
ATOM 7523 C CG  . GLN E 5 428 ? 104.746 126.834 107.133 1.00 97.64  ? 322 GLN D CG  1 
ATOM 7524 C CD  . GLN E 5 428 ? 104.393 128.302 107.278 1.00 99.18  ? 322 GLN D CD  1 
ATOM 7525 O OE1 . GLN E 5 428 ? 104.748 128.942 108.267 1.00 99.33  ? 322 GLN D OE1 1 
ATOM 7526 N NE2 . GLN E 5 428 ? 103.684 128.842 106.293 1.00 97.38  ? 322 GLN D NE2 1 
ATOM 7527 N N   . GLY E 5 429 ? 102.340 123.940 108.891 1.00 97.85  ? 323 GLY D N   1 
ATOM 7528 C CA  . GLY E 5 429 ? 101.378 123.054 108.261 1.00 98.26  ? 323 GLY D CA  1 
ATOM 7529 C C   . GLY E 5 429 ? 99.957  123.179 108.758 1.00 98.45  ? 323 GLY D C   1 
ATOM 7530 O O   . GLY E 5 429 ? 99.067  122.525 108.203 1.00 98.57  ? 323 GLY D O   1 
ATOM 7531 N N   . PHE E 5 430 ? 99.716  123.999 109.782 1.00 95.95  ? 324 PHE D N   1 
ATOM 7532 C CA  . PHE E 5 430 ? 98.376  124.164 110.325 1.00 96.55  ? 324 PHE D CA  1 
ATOM 7533 C C   . PHE E 5 430 ? 97.999  125.615 110.589 1.00 97.33  ? 324 PHE D C   1 
ATOM 7534 O O   . PHE E 5 430 ? 96.832  125.881 110.897 1.00 96.99  ? 324 PHE D O   1 
ATOM 7535 C CB  . PHE E 5 430 ? 98.218  123.362 111.628 1.00 97.51  ? 324 PHE D CB  1 
ATOM 7536 C CG  . PHE E 5 430 ? 96.799  123.238 112.091 1.00 97.18  ? 324 PHE D CG  1 
ATOM 7537 C CD1 . PHE E 5 430 ? 95.906  122.435 111.405 1.00 95.95  ? 324 PHE D CD1 1 
ATOM 7538 C CD2 . PHE E 5 430 ? 96.353  123.927 113.209 1.00 96.47  ? 324 PHE D CD2 1 
ATOM 7539 C CE1 . PHE E 5 430 ? 94.598  122.319 111.825 1.00 96.15  ? 324 PHE D CE1 1 
ATOM 7540 C CE2 . PHE E 5 430 ? 95.044  123.813 113.632 1.00 95.86  ? 324 PHE D CE2 1 
ATOM 7541 C CZ  . PHE E 5 430 ? 94.167  123.010 112.939 1.00 96.49  ? 324 PHE D CZ  1 
ATOM 7542 N N   . ARG E 5 431 ? 98.932  126.554 110.471 1.00 99.33  ? 325 ARG D N   1 
ATOM 7543 C CA  . ARG E 5 431 ? 98.641  127.954 110.738 1.00 99.77  ? 325 ARG D CA  1 
ATOM 7544 C C   . ARG E 5 431 ? 99.652  128.872 110.056 1.00 99.31  ? 325 ARG D C   1 
ATOM 7545 O O   . ARG E 5 431 ? 99.529  130.096 110.099 1.00 99.41  ? 325 ARG D O   1 
ATOM 7546 C CB  . ARG E 5 431 ? 98.623  128.210 112.243 1.00 98.65  ? 325 ARG D CB  1 
ATOM 7547 C CG  . ARG E 5 431 ? 98.196  129.611 112.608 1.00 98.49  ? 325 ARG D CG  1 
ATOM 7548 C CD  . ARG E 5 431 ? 98.138  129.802 114.111 1.00 99.73  ? 325 ARG D CD  1 
ATOM 7549 N NE  . ARG E 5 431 ? 97.112  128.980 114.735 1.00 100.93 ? 325 ARG D NE  1 
ATOM 7550 C CZ  . ARG E 5 431 ? 97.345  127.944 115.532 1.00 100.29 ? 325 ARG D CZ  1 
ATOM 7551 N NH1 . ARG E 5 431 ? 98.575  127.548 115.813 1.00 99.58  ? 325 ARG D NH1 1 
ATOM 7552 N NH2 . ARG E 5 431 ? 96.315  127.282 116.057 1.00 98.83  ? 325 ARG D NH2 1 
ATOM 7553 N N   . CYS F 6 3   ? 110.707 94.726  155.196 1.00 133.02 ? 3   CYS S N   1 
ATOM 7554 C CA  . CYS F 6 3   ? 109.696 95.812  155.332 1.00 133.78 ? 3   CYS S CA  1 
ATOM 7555 C C   . CYS F 6 3   ? 109.258 96.358  153.979 1.00 133.70 ? 3   CYS S C   1 
ATOM 7556 O O   . CYS F 6 3   ? 108.080 96.648  153.768 1.00 133.22 ? 3   CYS S O   1 
ATOM 7557 C CB  . CYS F 6 3   ? 110.259 96.949  156.176 1.00 134.15 ? 3   CYS S CB  1 
ATOM 7558 S SG  . CYS F 6 3   ? 109.059 97.779  157.229 1.00 134.46 ? 3   CYS S SG  1 
ATOM 7559 N N   . LYS F 6 4   ? 110.213 96.488  153.059 1.00 130.04 ? 4   LYS S N   1 
ATOM 7560 C CA  . LYS F 6 4   ? 109.967 97.096  151.755 1.00 130.32 ? 4   LYS S CA  1 
ATOM 7561 C C   . LYS F 6 4   ? 109.508 98.549  151.906 1.00 129.81 ? 4   LYS S C   1 
ATOM 7562 O O   . LYS F 6 4   ? 108.378 98.914  151.577 1.00 129.48 ? 4   LYS S O   1 
ATOM 7563 C CB  . LYS F 6 4   ? 108.947 96.269  150.972 1.00 130.09 ? 4   LYS S CB  1 
ATOM 7564 C CG  . LYS F 6 4   ? 108.816 96.673  149.525 1.00 129.48 ? 4   LYS S CG  1 
ATOM 7565 C CD  . LYS F 6 4   ? 107.830 95.782  148.797 1.00 129.10 ? 4   LYS S CD  1 
ATOM 7566 C CE  . LYS F 6 4   ? 108.397 94.388  148.568 1.00 129.28 ? 4   LYS S CE  1 
ATOM 7567 N NZ  . LYS F 6 4   ? 109.569 94.394  147.651 1.00 129.28 ? 4   LYS S NZ  1 
ATOM 7568 N N   . ASN F 6 5   ? 110.417 99.375  152.430 1.00 127.14 ? 5   ASN S N   1 
ATOM 7569 C CA  . ASN F 6 5   ? 110.147 100.802 152.589 1.00 126.95 ? 5   ASN S CA  1 
ATOM 7570 C C   . ASN F 6 5   ? 109.678 101.419 151.274 1.00 126.72 ? 5   ASN S C   1 
ATOM 7571 O O   . ASN F 6 5   ? 108.547 101.902 151.162 1.00 126.88 ? 5   ASN S O   1 
ATOM 7572 C CB  . ASN F 6 5   ? 111.408 101.503 153.103 1.00 126.92 ? 5   ASN S CB  1 
ATOM 7573 C CG  . ASN F 6 5   ? 111.167 102.952 153.475 1.00 127.37 ? 5   ASN S CG  1 
ATOM 7574 O OD1 . ASN F 6 5   ? 111.671 103.864 152.819 1.00 127.76 ? 5   ASN S OD1 1 
ATOM 7575 N ND2 . ASN F 6 5   ? 110.404 103.172 154.537 1.00 127.25 ? 5   ASN S ND2 1 
ATOM 7576 N N   . PHE F 6 6   ? 110.540 101.394 150.259 1.00 117.09 ? 6   PHE S N   1 
ATOM 7577 C CA  . PHE F 6 6   ? 110.178 101.841 148.915 1.00 116.96 ? 6   PHE S CA  1 
ATOM 7578 C C   . PHE F 6 6   ? 111.094 101.118 147.941 1.00 116.33 ? 6   PHE S C   1 
ATOM 7579 O O   . PHE F 6 6   ? 112.268 101.479 147.817 1.00 117.26 ? 6   PHE S O   1 
ATOM 7580 C CB  . PHE F 6 6   ? 110.317 103.354 148.762 1.00 116.01 ? 6   PHE S CB  1 
ATOM 7581 C CG  . PHE F 6 6   ? 109.288 104.137 149.515 1.00 116.75 ? 6   PHE S CG  1 
ATOM 7582 C CD1 . PHE F 6 6   ? 108.021 104.334 148.989 1.00 117.11 ? 6   PHE S CD1 1 
ATOM 7583 C CD2 . PHE F 6 6   ? 109.588 104.683 150.750 1.00 116.46 ? 6   PHE S CD2 1 
ATOM 7584 C CE1 . PHE F 6 6   ? 107.074 105.060 149.686 1.00 116.23 ? 6   PHE S CE1 1 
ATOM 7585 C CE2 . PHE F 6 6   ? 108.647 105.407 151.450 1.00 116.26 ? 6   PHE S CE2 1 
ATOM 7586 C CZ  . PHE F 6 6   ? 107.390 105.596 150.917 1.00 116.20 ? 6   PHE S CZ  1 
ATOM 7587 N N   . PHE F 6 7   ? 110.570 100.103 147.257 1.00 111.77 ? 7   PHE S N   1 
ATOM 7588 C CA  . PHE F 6 7   ? 111.376 99.364  146.292 1.00 112.16 ? 7   PHE S CA  1 
ATOM 7589 C C   . PHE F 6 7   ? 111.211 99.922  144.881 1.00 113.49 ? 7   PHE S C   1 
ATOM 7590 O O   . PHE F 6 7   ? 112.174 100.407 144.280 1.00 113.79 ? 7   PHE S O   1 
ATOM 7591 C CB  . PHE F 6 7   ? 111.005 97.879  146.323 1.00 112.07 ? 7   PHE S CB  1 
ATOM 7592 C CG  . PHE F 6 7   ? 111.395 97.141  145.082 1.00 112.53 ? 7   PHE S CG  1 
ATOM 7593 C CD1 . PHE F 6 7   ? 112.724 97.041  144.710 1.00 112.90 ? 7   PHE S CD1 1 
ATOM 7594 C CD2 . PHE F 6 7   ? 110.433 96.550  144.282 1.00 112.52 ? 7   PHE S CD2 1 
ATOM 7595 C CE1 . PHE F 6 7   ? 113.084 96.367  143.564 1.00 113.04 ? 7   PHE S CE1 1 
ATOM 7596 C CE2 . PHE F 6 7   ? 110.791 95.872  143.137 1.00 113.91 ? 7   PHE S CE2 1 
ATOM 7597 C CZ  . PHE F 6 7   ? 112.118 95.782  142.779 1.00 113.52 ? 7   PHE S CZ  1 
ATOM 7598 N N   . TRP F 6 8   ? 109.992 99.866  144.343 1.00 104.78 ? 8   TRP S N   1 
ATOM 7599 C CA  . TRP F 6 8   ? 109.735 100.324 142.977 1.00 102.46 ? 8   TRP S CA  1 
ATOM 7600 C C   . TRP F 6 8   ? 108.291 100.826 142.934 1.00 102.00 ? 8   TRP S C   1 
ATOM 7601 O O   . TRP F 6 8   ? 107.361 100.060 142.674 1.00 103.04 ? 8   TRP S O   1 
ATOM 7602 C CB  . TRP F 6 8   ? 109.978 99.199  141.981 1.00 102.82 ? 8   TRP S CB  1 
ATOM 7603 C CG  . TRP F 6 8   ? 109.688 99.537  140.553 1.00 101.73 ? 8   TRP S CG  1 
ATOM 7604 C CD1 . TRP F 6 8   ? 108.469 99.537  139.942 1.00 101.90 ? 8   TRP S CD1 1 
ATOM 7605 C CD2 . TRP F 6 8   ? 110.641 99.899  139.547 1.00 101.49 ? 8   TRP S CD2 1 
ATOM 7606 N NE1 . TRP F 6 8   ? 108.604 99.887  138.620 1.00 101.75 ? 8   TRP S NE1 1 
ATOM 7607 C CE2 . TRP F 6 8   ? 109.927 100.114 138.353 1.00 100.90 ? 8   TRP S CE2 1 
ATOM 7608 C CE3 . TRP F 6 8   ? 112.028 100.067 139.541 1.00 102.35 ? 8   TRP S CE3 1 
ATOM 7609 C CZ2 . TRP F 6 8   ? 110.552 100.489 137.168 1.00 101.01 ? 8   TRP S CZ2 1 
ATOM 7610 C CZ3 . TRP F 6 8   ? 112.645 100.440 138.364 1.00 103.41 ? 8   TRP S CZ3 1 
ATOM 7611 C CH2 . TRP F 6 8   ? 111.909 100.646 137.194 1.00 102.19 ? 8   TRP S CH2 1 
ATOM 7612 N N   . LYS F 6 9   ? 108.122 102.122 143.185 1.00 100.40 ? 9   LYS S N   1 
ATOM 7613 C CA  . LYS F 6 9   ? 106.820 102.781 143.129 1.00 101.00 ? 9   LYS S CA  1 
ATOM 7614 C C   . LYS F 6 9   ? 105.790 102.139 144.058 1.00 100.98 ? 9   LYS S C   1 
ATOM 7615 O O   . LYS F 6 9   ? 104.586 102.339 143.876 1.00 102.09 ? 9   LYS S O   1 
ATOM 7616 C CB  . LYS F 6 9   ? 106.284 102.800 141.693 1.00 100.20 ? 9   LYS S CB  1 
ATOM 7617 C CG  . LYS F 6 9   ? 107.228 103.444 140.690 1.00 99.99  ? 9   LYS S CG  1 
ATOM 7618 C CD  . LYS F 6 9   ? 106.655 103.428 139.285 1.00 100.35 ? 9   LYS S CD  1 
ATOM 7619 C CE  . LYS F 6 9   ? 107.573 104.137 138.304 1.00 99.17  ? 9   LYS S CE  1 
ATOM 7620 N NZ  . LYS F 6 9   ? 107.060 104.075 136.909 1.00 97.98  ? 9   LYS S NZ  1 
ATOM 7621 N N   . THR F 6 10  ? 106.225 101.371 145.058 1.00 109.04 ? 10  THR S N   1 
ATOM 7622 C CA  . THR F 6 10  ? 105.301 100.640 145.916 1.00 109.30 ? 10  THR S CA  1 
ATOM 7623 C C   . THR F 6 10  ? 105.874 100.544 147.325 1.00 110.52 ? 10  THR S C   1 
ATOM 7624 O O   . THR F 6 10  ? 107.041 100.857 147.571 1.00 110.19 ? 10  THR S O   1 
ATOM 7625 C CB  . THR F 6 10  ? 105.011 99.238  145.362 1.00 109.75 ? 10  THR S CB  1 
ATOM 7626 O OG1 . THR F 6 10  ? 106.241 98.529  145.173 1.00 109.32 ? 10  THR S OG1 1 
ATOM 7627 C CG2 . THR F 6 10  ? 104.261 99.319  144.034 1.00 109.18 ? 10  THR S CG2 1 
ATOM 7628 N N   . PHE F 6 11  ? 105.022 100.106 148.251 1.00 124.01 ? 11  PHE S N   1 
ATOM 7629 C CA  . PHE F 6 11  ? 105.376 99.964  149.658 1.00 124.32 ? 11  PHE S CA  1 
ATOM 7630 C C   . PHE F 6 11  ? 104.388 99.003  150.301 1.00 123.87 ? 11  PHE S C   1 
ATOM 7631 O O   . PHE F 6 11  ? 103.279 98.802  149.800 1.00 123.25 ? 11  PHE S O   1 
ATOM 7632 C CB  . PHE F 6 11  ? 105.351 101.312 150.381 1.00 123.87 ? 11  PHE S CB  1 
ATOM 7633 C CG  . PHE F 6 11  ? 103.977 101.743 150.790 1.00 123.53 ? 11  PHE S CG  1 
ATOM 7634 C CD1 . PHE F 6 11  ? 102.993 101.949 149.840 1.00 123.81 ? 11  PHE S CD1 1 
ATOM 7635 C CD2 . PHE F 6 11  ? 103.666 101.940 152.121 1.00 123.49 ? 11  PHE S CD2 1 
ATOM 7636 C CE1 . PHE F 6 11  ? 101.726 102.344 150.207 1.00 123.96 ? 11  PHE S CE1 1 
ATOM 7637 C CE2 . PHE F 6 11  ? 102.398 102.341 152.495 1.00 123.86 ? 11  PHE S CE2 1 
ATOM 7638 C CZ  . PHE F 6 11  ? 101.427 102.541 151.535 1.00 123.50 ? 11  PHE S CZ  1 
ATOM 7639 N N   . THR F 6 12  ? 104.803 98.411  151.427 1.00 132.18 ? 12  THR S N   1 
ATOM 7640 C CA  . THR F 6 12  ? 103.963 97.493  152.202 1.00 132.52 ? 12  THR S CA  1 
ATOM 7641 C C   . THR F 6 12  ? 104.040 97.876  153.680 1.00 132.88 ? 12  THR S C   1 
ATOM 7642 O O   . THR F 6 12  ? 104.778 97.261  154.453 1.00 133.15 ? 12  THR S O   1 
ATOM 7643 C CB  . THR F 6 12  ? 104.403 96.047  151.981 1.00 132.93 ? 12  THR S CB  1 
ATOM 7644 O OG1 . THR F 6 12  ? 105.770 95.899  152.384 1.00 132.74 ? 12  THR S OG1 1 
ATOM 7645 C CG2 . THR F 6 12  ? 104.260 95.660  150.514 1.00 132.47 ? 12  THR S CG2 1 
ATOM 7646 N N   . SER F 6 13  ? 103.250 98.874  154.073 1.00 131.33 ? 13  SER S N   1 
ATOM 7647 C CA  . SER F 6 13  ? 103.060 99.215  155.482 1.00 131.24 ? 13  SER S CA  1 
ATOM 7648 C C   . SER F 6 13  ? 104.389 99.389  156.214 1.00 131.46 ? 13  SER S C   1 
ATOM 7649 O O   . SER F 6 13  ? 104.612 98.813  157.280 1.00 130.80 ? 13  SER S O   1 
ATOM 7650 C CB  . SER F 6 13  ? 102.205 98.156  156.175 1.00 130.86 ? 13  SER S CB  1 
ATOM 7651 O OG  . SER F 6 13  ? 102.885 96.913  156.253 1.00 130.81 ? 13  SER S OG  1 
ATOM 7652 N N   . CYS F 6 14  ? 105.287 100.185 155.643 1.00 135.54 ? 14  CYS S N   1 
ATOM 7653 C CA  . CYS F 6 14  ? 106.534 100.481 156.340 1.00 135.46 ? 14  CYS S CA  1 
ATOM 7654 C C   . CYS F 6 14  ? 106.703 101.979 156.577 1.00 135.17 ? 14  CYS S C   1 
ATOM 7655 O O   . CYS F 6 14  ? 106.914 102.415 157.710 1.00 134.97 ? 14  CYS S O   1 
ATOM 7656 C CB  . CYS F 6 14  ? 107.736 99.938  155.569 1.00 135.31 ? 14  CYS S CB  1 
ATOM 7657 S SG  . CYS F 6 14  ? 109.174 99.714  156.625 1.00 135.92 ? 14  CYS S SG  1 
# 
