data_8ZBG
# 
_entry.id   8ZBG 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8ZBG         pdb_00008zbg 10.2210/pdb8zbg/pdb 
WWPDB D_1300047365 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-04-16 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8ZBG 
_pdbx_database_status.recvd_initial_deposition_date   2024-04-26 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           N 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              hs_kim@baobabaibio.com 
_pdbx_contact_author.name_first         Hanseong 
_pdbx_contact_author.name_last          Kim 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0001-7518-6936 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Yoo, Y.' 1 0000-0001-7848-412X 
'Kim, H.' 2 0000-0001-7518-6936 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            J.Med.Chem. 
_citation.journal_id_ASTM           JMCMAR 
_citation.journal_id_CSD            0151 
_citation.journal_id_ISSN           0022-2623 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            67 
_citation.language                  ? 
_citation.page_first                18957 
_citation.page_last                 18968 
_citation.title                     'Pan-Transcriptional Enhanced Associated Domain Palmitoylation Pocket Covalent Inhibitor.' 
_citation.year                      2024 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1021/acs.jmedchem.4c01393 
_citation.pdbx_database_id_PubMed   39487823 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Kim, J.'     1  0009-0007-0533-1414 
primary 'Kim, H.'     2  ?                   
primary 'Kim, J.'     3  ?                   
primary 'Cho, S.Y.'   4  ?                   
primary 'Moon, S.'    5  ?                   
primary 'Yoo, Y.'     6  ?                   
primary 'Kim, H.'     7  0000-0001-7518-6936 
primary 'Kim, J.K.'   8  ?                   
primary 'Jeon, H.'    9  ?                   
primary 'Namkung, W.' 10 0000-0002-1480-7433 
primary 'Han, G.'     11 0000-0002-2175-5248 
primary 'No, K.T.'    12 0000-0003-3187-8193 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Transcriptional enhancer factor TEF-5'                                                                25395.867 
3  ? ? ? ? 
2 non-polymer syn '(2~{R})-2-fluoranyl-1-[7-[4-(trifluoromethyl)phenyl]-3,4-dihydro-1~{H}-isoquinolin-2-yl]propan-1-one' 351.338   
3  ? ? ? ? 
3 water       nat water                                                                                                  18.015    
34 ? ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        'DTEF-1,TEA domain family member 3,TEAD-3' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;SQDRTIASSRLRLLEYSAFMEVQRDPDTYSKHLFVHIGQTNPAFSDPPLEAVDVRQIYDKFPEKKGGLKELYEKGPPNAF
FLVKFWADLNSTIQEGPGAFYGVSSQYSSADSMTISVSTKVCSFGKQVVEKVETEYARLENGRFVYRIHRSPMCEYMINF
IHKLKHLPEKYMMNSVLENFTILQVVTSRDSQETLLVIAFVFEVSTSEHGAQHHVYKLVKD
;
_entity_poly.pdbx_seq_one_letter_code_can   
;SQDRTIASSRLRLLEYSAFMEVQRDPDTYSKHLFVHIGQTNPAFSDPPLEAVDVRQIYDKFPEKKGGLKELYEKGPPNAF
FLVKFWADLNSTIQEGPGAFYGVSSQYSSADSMTISVSTKVCSFGKQVVEKVETEYARLENGRFVYRIHRSPMCEYMINF
IHKLKHLPEKYMMNSVLENFTILQVVTSRDSQETLLVIAFVFEVSTSEHGAQHHVYKLVKD
;
_entity_poly.pdbx_strand_id                 A,B,C 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 '(2~{R})-2-fluoranyl-1-[7-[4-(trifluoromethyl)phenyl]-3,4-dihydro-1~{H}-isoquinolin-2-yl]propan-1-one' A1L1N 
3 water                                                                                                  HOH   
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   SER n 
1 2   GLN n 
1 3   ASP n 
1 4   ARG n 
1 5   THR n 
1 6   ILE n 
1 7   ALA n 
1 8   SER n 
1 9   SER n 
1 10  ARG n 
1 11  LEU n 
1 12  ARG n 
1 13  LEU n 
1 14  LEU n 
1 15  GLU n 
1 16  TYR n 
1 17  SER n 
1 18  ALA n 
1 19  PHE n 
1 20  MET n 
1 21  GLU n 
1 22  VAL n 
1 23  GLN n 
1 24  ARG n 
1 25  ASP n 
1 26  PRO n 
1 27  ASP n 
1 28  THR n 
1 29  TYR n 
1 30  SER n 
1 31  LYS n 
1 32  HIS n 
1 33  LEU n 
1 34  PHE n 
1 35  VAL n 
1 36  HIS n 
1 37  ILE n 
1 38  GLY n 
1 39  GLN n 
1 40  THR n 
1 41  ASN n 
1 42  PRO n 
1 43  ALA n 
1 44  PHE n 
1 45  SER n 
1 46  ASP n 
1 47  PRO n 
1 48  PRO n 
1 49  LEU n 
1 50  GLU n 
1 51  ALA n 
1 52  VAL n 
1 53  ASP n 
1 54  VAL n 
1 55  ARG n 
1 56  GLN n 
1 57  ILE n 
1 58  TYR n 
1 59  ASP n 
1 60  LYS n 
1 61  PHE n 
1 62  PRO n 
1 63  GLU n 
1 64  LYS n 
1 65  LYS n 
1 66  GLY n 
1 67  GLY n 
1 68  LEU n 
1 69  LYS n 
1 70  GLU n 
1 71  LEU n 
1 72  TYR n 
1 73  GLU n 
1 74  LYS n 
1 75  GLY n 
1 76  PRO n 
1 77  PRO n 
1 78  ASN n 
1 79  ALA n 
1 80  PHE n 
1 81  PHE n 
1 82  LEU n 
1 83  VAL n 
1 84  LYS n 
1 85  PHE n 
1 86  TRP n 
1 87  ALA n 
1 88  ASP n 
1 89  LEU n 
1 90  ASN n 
1 91  SER n 
1 92  THR n 
1 93  ILE n 
1 94  GLN n 
1 95  GLU n 
1 96  GLY n 
1 97  PRO n 
1 98  GLY n 
1 99  ALA n 
1 100 PHE n 
1 101 TYR n 
1 102 GLY n 
1 103 VAL n 
1 104 SER n 
1 105 SER n 
1 106 GLN n 
1 107 TYR n 
1 108 SER n 
1 109 SER n 
1 110 ALA n 
1 111 ASP n 
1 112 SER n 
1 113 MET n 
1 114 THR n 
1 115 ILE n 
1 116 SER n 
1 117 VAL n 
1 118 SER n 
1 119 THR n 
1 120 LYS n 
1 121 VAL n 
1 122 CYS n 
1 123 SER n 
1 124 PHE n 
1 125 GLY n 
1 126 LYS n 
1 127 GLN n 
1 128 VAL n 
1 129 VAL n 
1 130 GLU n 
1 131 LYS n 
1 132 VAL n 
1 133 GLU n 
1 134 THR n 
1 135 GLU n 
1 136 TYR n 
1 137 ALA n 
1 138 ARG n 
1 139 LEU n 
1 140 GLU n 
1 141 ASN n 
1 142 GLY n 
1 143 ARG n 
1 144 PHE n 
1 145 VAL n 
1 146 TYR n 
1 147 ARG n 
1 148 ILE n 
1 149 HIS n 
1 150 ARG n 
1 151 SER n 
1 152 PRO n 
1 153 MET n 
1 154 CYS n 
1 155 GLU n 
1 156 TYR n 
1 157 MET n 
1 158 ILE n 
1 159 ASN n 
1 160 PHE n 
1 161 ILE n 
1 162 HIS n 
1 163 LYS n 
1 164 LEU n 
1 165 LYS n 
1 166 HIS n 
1 167 LEU n 
1 168 PRO n 
1 169 GLU n 
1 170 LYS n 
1 171 TYR n 
1 172 MET n 
1 173 MET n 
1 174 ASN n 
1 175 SER n 
1 176 VAL n 
1 177 LEU n 
1 178 GLU n 
1 179 ASN n 
1 180 PHE n 
1 181 THR n 
1 182 ILE n 
1 183 LEU n 
1 184 GLN n 
1 185 VAL n 
1 186 VAL n 
1 187 THR n 
1 188 SER n 
1 189 ARG n 
1 190 ASP n 
1 191 SER n 
1 192 GLN n 
1 193 GLU n 
1 194 THR n 
1 195 LEU n 
1 196 LEU n 
1 197 VAL n 
1 198 ILE n 
1 199 ALA n 
1 200 PHE n 
1 201 VAL n 
1 202 PHE n 
1 203 GLU n 
1 204 VAL n 
1 205 SER n 
1 206 THR n 
1 207 SER n 
1 208 GLU n 
1 209 HIS n 
1 210 GLY n 
1 211 ALA n 
1 212 GLN n 
1 213 HIS n 
1 214 HIS n 
1 215 VAL n 
1 216 TYR n 
1 217 LYS n 
1 218 LEU n 
1 219 VAL n 
1 220 LYS n 
1 221 ASP n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   221 
_entity_src_gen.gene_src_common_name               human 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 'TEAD3, TEAD5, TEF5' 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     9606 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
A1L1N non-polymer         . '(2~{R})-2-fluoranyl-1-[7-[4-(trifluoromethyl)phenyl]-3,4-dihydro-1~{H}-isoquinolin-2-yl]propan-1-one' 
? 'C19 H17 F4 N O' 351.338 
ALA   'L-peptide linking' y ALANINE                                                                                                
? 'C3 H7 N O2'     89.093  
ARG   'L-peptide linking' y ARGININE                                                                                               
? 'C6 H15 N4 O2 1' 175.209 
ASN   'L-peptide linking' y ASPARAGINE                                                                                             
? 'C4 H8 N2 O3'    132.118 
ASP   'L-peptide linking' y 'ASPARTIC ACID'                                                                                        
? 'C4 H7 N O4'     133.103 
CYS   'L-peptide linking' y CYSTEINE                                                                                               
? 'C3 H7 N O2 S'   121.158 
GLN   'L-peptide linking' y GLUTAMINE                                                                                              
? 'C5 H10 N2 O3'   146.144 
GLU   'L-peptide linking' y 'GLUTAMIC ACID'                                                                                        
? 'C5 H9 N O4'     147.129 
GLY   'peptide linking'   y GLYCINE                                                                                                
? 'C2 H5 N O2'     75.067  
HIS   'L-peptide linking' y HISTIDINE                                                                                              
? 'C6 H10 N3 O2 1' 156.162 
HOH   non-polymer         . WATER                                                                                                  
? 'H2 O'           18.015  
ILE   'L-peptide linking' y ISOLEUCINE                                                                                             
? 'C6 H13 N O2'    131.173 
LEU   'L-peptide linking' y LEUCINE                                                                                                
? 'C6 H13 N O2'    131.173 
LYS   'L-peptide linking' y LYSINE                                                                                                 
? 'C6 H15 N2 O2 1' 147.195 
MET   'L-peptide linking' y METHIONINE                                                                                             
? 'C5 H11 N O2 S'  149.211 
PHE   'L-peptide linking' y PHENYLALANINE                                                                                          
? 'C9 H11 N O2'    165.189 
PRO   'L-peptide linking' y PROLINE                                                                                                
? 'C5 H9 N O2'     115.130 
SER   'L-peptide linking' y SERINE                                                                                                 
? 'C3 H7 N O3'     105.093 
THR   'L-peptide linking' y THREONINE                                                                                              
? 'C4 H9 N O3'     119.119 
TRP   'L-peptide linking' y TRYPTOPHAN                                                                                             
? 'C11 H12 N2 O2'  204.225 
TYR   'L-peptide linking' y TYROSINE                                                                                               
? 'C9 H11 N O3'    181.189 
VAL   'L-peptide linking' y VALINE                                                                                                 
? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   SER 1   215 ?   ?   ?   A . n 
A 1 2   GLN 2   216 ?   ?   ?   A . n 
A 1 3   ASP 3   217 217 ASP ASP A . n 
A 1 4   ARG 4   218 218 ARG ARG A . n 
A 1 5   THR 5   219 219 THR THR A . n 
A 1 6   ILE 6   220 220 ILE ILE A . n 
A 1 7   ALA 7   221 221 ALA ALA A . n 
A 1 8   SER 8   222 222 SER SER A . n 
A 1 9   SER 9   223 223 SER SER A . n 
A 1 10  ARG 10  224 224 ARG ARG A . n 
A 1 11  LEU 11  225 225 LEU LEU A . n 
A 1 12  ARG 12  226 226 ARG ARG A . n 
A 1 13  LEU 13  227 227 LEU LEU A . n 
A 1 14  LEU 14  228 228 LEU LEU A . n 
A 1 15  GLU 15  229 229 GLU GLU A . n 
A 1 16  TYR 16  230 230 TYR TYR A . n 
A 1 17  SER 17  231 231 SER SER A . n 
A 1 18  ALA 18  232 232 ALA ALA A . n 
A 1 19  PHE 19  233 233 PHE PHE A . n 
A 1 20  MET 20  234 234 MET MET A . n 
A 1 21  GLU 21  235 235 GLU GLU A . n 
A 1 22  VAL 22  236 236 VAL VAL A . n 
A 1 23  GLN 23  237 237 GLN GLN A . n 
A 1 24  ARG 24  238 238 ARG ARG A . n 
A 1 25  ASP 25  239 239 ASP ASP A . n 
A 1 26  PRO 26  240 240 PRO PRO A . n 
A 1 27  ASP 27  241 241 ASP ASP A . n 
A 1 28  THR 28  242 242 THR THR A . n 
A 1 29  TYR 29  243 243 TYR TYR A . n 
A 1 30  SER 30  244 244 SER SER A . n 
A 1 31  LYS 31  245 245 LYS LYS A . n 
A 1 32  HIS 32  246 246 HIS HIS A . n 
A 1 33  LEU 33  247 247 LEU LEU A . n 
A 1 34  PHE 34  248 248 PHE PHE A . n 
A 1 35  VAL 35  249 249 VAL VAL A . n 
A 1 36  HIS 36  250 250 HIS HIS A . n 
A 1 37  ILE 37  251 251 ILE ILE A . n 
A 1 38  GLY 38  252 252 GLY GLY A . n 
A 1 39  GLN 39  253 253 GLN GLN A . n 
A 1 40  THR 40  254 254 THR THR A . n 
A 1 41  ASN 41  255 255 ASN ASN A . n 
A 1 42  PRO 42  256 256 PRO PRO A . n 
A 1 43  ALA 43  257 257 ALA ALA A . n 
A 1 44  PHE 44  258 258 PHE PHE A . n 
A 1 45  SER 45  259 259 SER SER A . n 
A 1 46  ASP 46  260 260 ASP ASP A . n 
A 1 47  PRO 47  261 261 PRO PRO A . n 
A 1 48  PRO 48  262 262 PRO PRO A . n 
A 1 49  LEU 49  263 263 LEU LEU A . n 
A 1 50  GLU 50  264 264 GLU GLU A . n 
A 1 51  ALA 51  265 265 ALA ALA A . n 
A 1 52  VAL 52  266 266 VAL VAL A . n 
A 1 53  ASP 53  267 267 ASP ASP A . n 
A 1 54  VAL 54  268 268 VAL VAL A . n 
A 1 55  ARG 55  269 269 ARG ARG A . n 
A 1 56  GLN 56  270 270 GLN GLN A . n 
A 1 57  ILE 57  271 271 ILE ILE A . n 
A 1 58  TYR 58  272 272 TYR TYR A . n 
A 1 59  ASP 59  273 273 ASP ASP A . n 
A 1 60  LYS 60  274 274 LYS LYS A . n 
A 1 61  PHE 61  275 275 PHE PHE A . n 
A 1 62  PRO 62  276 276 PRO PRO A . n 
A 1 63  GLU 63  277 277 GLU GLU A . n 
A 1 64  LYS 64  278 278 LYS LYS A . n 
A 1 65  LYS 65  279 279 LYS LYS A . n 
A 1 66  GLY 66  280 280 GLY GLY A . n 
A 1 67  GLY 67  281 281 GLY GLY A . n 
A 1 68  LEU 68  282 282 LEU LEU A . n 
A 1 69  LYS 69  283 283 LYS LYS A . n 
A 1 70  GLU 70  284 284 GLU GLU A . n 
A 1 71  LEU 71  285 285 LEU LEU A . n 
A 1 72  TYR 72  286 286 TYR TYR A . n 
A 1 73  GLU 73  287 287 GLU GLU A . n 
A 1 74  LYS 74  288 288 LYS LYS A . n 
A 1 75  GLY 75  289 289 GLY GLY A . n 
A 1 76  PRO 76  290 290 PRO PRO A . n 
A 1 77  PRO 77  291 291 PRO PRO A . n 
A 1 78  ASN 78  292 292 ASN ASN A . n 
A 1 79  ALA 79  293 293 ALA ALA A . n 
A 1 80  PHE 80  294 294 PHE PHE A . n 
A 1 81  PHE 81  295 295 PHE PHE A . n 
A 1 82  LEU 82  296 296 LEU LEU A . n 
A 1 83  VAL 83  297 297 VAL VAL A . n 
A 1 84  LYS 84  298 298 LYS LYS A . n 
A 1 85  PHE 85  299 299 PHE PHE A . n 
A 1 86  TRP 86  300 300 TRP TRP A . n 
A 1 87  ALA 87  301 301 ALA ALA A . n 
A 1 88  ASP 88  302 302 ASP ASP A . n 
A 1 89  LEU 89  303 303 LEU LEU A . n 
A 1 90  ASN 90  304 304 ASN ASN A . n 
A 1 91  SER 91  305 305 SER SER A . n 
A 1 92  THR 92  306 306 THR THR A . n 
A 1 93  ILE 93  307 307 ILE ILE A . n 
A 1 94  GLN 94  308 308 GLN GLN A . n 
A 1 95  GLU 95  309 309 GLU GLU A . n 
A 1 96  GLY 96  310 310 GLY GLY A . n 
A 1 97  PRO 97  311 311 PRO PRO A . n 
A 1 98  GLY 98  312 312 GLY GLY A . n 
A 1 99  ALA 99  313 313 ALA ALA A . n 
A 1 100 PHE 100 314 314 PHE PHE A . n 
A 1 101 TYR 101 315 315 TYR TYR A . n 
A 1 102 GLY 102 316 316 GLY GLY A . n 
A 1 103 VAL 103 317 317 VAL VAL A . n 
A 1 104 SER 104 318 318 SER SER A . n 
A 1 105 SER 105 319 319 SER SER A . n 
A 1 106 GLN 106 320 320 GLN GLN A . n 
A 1 107 TYR 107 321 321 TYR TYR A . n 
A 1 108 SER 108 322 322 SER SER A . n 
A 1 109 SER 109 323 323 SER SER A . n 
A 1 110 ALA 110 324 324 ALA ALA A . n 
A 1 111 ASP 111 325 325 ASP ASP A . n 
A 1 112 SER 112 326 326 SER SER A . n 
A 1 113 MET 113 327 327 MET MET A . n 
A 1 114 THR 114 328 328 THR THR A . n 
A 1 115 ILE 115 329 329 ILE ILE A . n 
A 1 116 SER 116 330 330 SER SER A . n 
A 1 117 VAL 117 331 331 VAL VAL A . n 
A 1 118 SER 118 332 332 SER SER A . n 
A 1 119 THR 119 333 333 THR THR A . n 
A 1 120 LYS 120 334 334 LYS LYS A . n 
A 1 121 VAL 121 335 335 VAL VAL A . n 
A 1 122 CYS 122 336 336 CYS CYS A . n 
A 1 123 SER 123 337 337 SER SER A . n 
A 1 124 PHE 124 338 338 PHE PHE A . n 
A 1 125 GLY 125 339 339 GLY GLY A . n 
A 1 126 LYS 126 340 340 LYS LYS A . n 
A 1 127 GLN 127 341 341 GLN GLN A . n 
A 1 128 VAL 128 342 342 VAL VAL A . n 
A 1 129 VAL 129 343 343 VAL VAL A . n 
A 1 130 GLU 130 344 344 GLU GLU A . n 
A 1 131 LYS 131 345 345 LYS LYS A . n 
A 1 132 VAL 132 346 346 VAL VAL A . n 
A 1 133 GLU 133 347 347 GLU GLU A . n 
A 1 134 THR 134 348 348 THR THR A . n 
A 1 135 GLU 135 349 349 GLU GLU A . n 
A 1 136 TYR 136 350 350 TYR TYR A . n 
A 1 137 ALA 137 351 351 ALA ALA A . n 
A 1 138 ARG 138 352 352 ARG ARG A . n 
A 1 139 LEU 139 353 353 LEU LEU A . n 
A 1 140 GLU 140 354 354 GLU GLU A . n 
A 1 141 ASN 141 355 355 ASN ASN A . n 
A 1 142 GLY 142 356 356 GLY GLY A . n 
A 1 143 ARG 143 357 357 ARG ARG A . n 
A 1 144 PHE 144 358 358 PHE PHE A . n 
A 1 145 VAL 145 359 359 VAL VAL A . n 
A 1 146 TYR 146 360 360 TYR TYR A . n 
A 1 147 ARG 147 361 361 ARG ARG A . n 
A 1 148 ILE 148 362 362 ILE ILE A . n 
A 1 149 HIS 149 363 363 HIS HIS A . n 
A 1 150 ARG 150 364 364 ARG ARG A . n 
A 1 151 SER 151 365 365 SER SER A . n 
A 1 152 PRO 152 366 366 PRO PRO A . n 
A 1 153 MET 153 367 367 MET MET A . n 
A 1 154 CYS 154 368 368 CYS CYS A . n 
A 1 155 GLU 155 369 369 GLU GLU A . n 
A 1 156 TYR 156 370 370 TYR TYR A . n 
A 1 157 MET 157 371 371 MET MET A . n 
A 1 158 ILE 158 372 372 ILE ILE A . n 
A 1 159 ASN 159 373 373 ASN ASN A . n 
A 1 160 PHE 160 374 374 PHE PHE A . n 
A 1 161 ILE 161 375 375 ILE ILE A . n 
A 1 162 HIS 162 376 376 HIS HIS A . n 
A 1 163 LYS 163 377 377 LYS LYS A . n 
A 1 164 LEU 164 378 378 LEU LEU A . n 
A 1 165 LYS 165 379 379 LYS LYS A . n 
A 1 166 HIS 166 380 380 HIS HIS A . n 
A 1 167 LEU 167 381 381 LEU LEU A . n 
A 1 168 PRO 168 382 382 PRO PRO A . n 
A 1 169 GLU 169 383 383 GLU GLU A . n 
A 1 170 LYS 170 384 384 LYS LYS A . n 
A 1 171 TYR 171 385 385 TYR TYR A . n 
A 1 172 MET 172 386 386 MET MET A . n 
A 1 173 MET 173 387 387 MET MET A . n 
A 1 174 ASN 174 388 388 ASN ASN A . n 
A 1 175 SER 175 389 389 SER SER A . n 
A 1 176 VAL 176 390 390 VAL VAL A . n 
A 1 177 LEU 177 391 391 LEU LEU A . n 
A 1 178 GLU 178 392 392 GLU GLU A . n 
A 1 179 ASN 179 393 393 ASN ASN A . n 
A 1 180 PHE 180 394 394 PHE PHE A . n 
A 1 181 THR 181 395 395 THR THR A . n 
A 1 182 ILE 182 396 396 ILE ILE A . n 
A 1 183 LEU 183 397 397 LEU LEU A . n 
A 1 184 GLN 184 398 398 GLN GLN A . n 
A 1 185 VAL 185 399 399 VAL VAL A . n 
A 1 186 VAL 186 400 400 VAL VAL A . n 
A 1 187 THR 187 401 401 THR THR A . n 
A 1 188 SER 188 402 402 SER SER A . n 
A 1 189 ARG 189 403 403 ARG ARG A . n 
A 1 190 ASP 190 404 404 ASP ASP A . n 
A 1 191 SER 191 405 405 SER SER A . n 
A 1 192 GLN 192 406 406 GLN GLN A . n 
A 1 193 GLU 193 407 407 GLU GLU A . n 
A 1 194 THR 194 408 408 THR THR A . n 
A 1 195 LEU 195 409 409 LEU LEU A . n 
A 1 196 LEU 196 410 410 LEU LEU A . n 
A 1 197 VAL 197 411 411 VAL VAL A . n 
A 1 198 ILE 198 412 412 ILE ILE A . n 
A 1 199 ALA 199 413 413 ALA ALA A . n 
A 1 200 PHE 200 414 414 PHE PHE A . n 
A 1 201 VAL 201 415 415 VAL VAL A . n 
A 1 202 PHE 202 416 416 PHE PHE A . n 
A 1 203 GLU 203 417 417 GLU GLU A . n 
A 1 204 VAL 204 418 418 VAL VAL A . n 
A 1 205 SER 205 419 419 SER SER A . n 
A 1 206 THR 206 420 420 THR THR A . n 
A 1 207 SER 207 421 421 SER SER A . n 
A 1 208 GLU 208 422 422 GLU GLU A . n 
A 1 209 HIS 209 423 423 HIS HIS A . n 
A 1 210 GLY 210 424 424 GLY GLY A . n 
A 1 211 ALA 211 425 425 ALA ALA A . n 
A 1 212 GLN 212 426 426 GLN GLN A . n 
A 1 213 HIS 213 427 427 HIS HIS A . n 
A 1 214 HIS 214 428 428 HIS HIS A . n 
A 1 215 VAL 215 429 429 VAL VAL A . n 
A 1 216 TYR 216 430 430 TYR TYR A . n 
A 1 217 LYS 217 431 431 LYS LYS A . n 
A 1 218 LEU 218 432 432 LEU LEU A . n 
A 1 219 VAL 219 433 433 VAL VAL A . n 
A 1 220 LYS 220 434 434 LYS LYS A . n 
A 1 221 ASP 221 435 435 ASP ASP A . n 
B 1 1   SER 1   215 215 SER SER B . n 
B 1 2   GLN 2   216 216 GLN GLN B . n 
B 1 3   ASP 3   217 217 ASP ASP B . n 
B 1 4   ARG 4   218 218 ARG ARG B . n 
B 1 5   THR 5   219 219 THR THR B . n 
B 1 6   ILE 6   220 220 ILE ILE B . n 
B 1 7   ALA 7   221 221 ALA ALA B . n 
B 1 8   SER 8   222 222 SER SER B . n 
B 1 9   SER 9   223 223 SER SER B . n 
B 1 10  ARG 10  224 224 ARG ARG B . n 
B 1 11  LEU 11  225 225 LEU LEU B . n 
B 1 12  ARG 12  226 226 ARG ARG B . n 
B 1 13  LEU 13  227 227 LEU LEU B . n 
B 1 14  LEU 14  228 228 LEU LEU B . n 
B 1 15  GLU 15  229 229 GLU GLU B . n 
B 1 16  TYR 16  230 230 TYR TYR B . n 
B 1 17  SER 17  231 231 SER SER B . n 
B 1 18  ALA 18  232 232 ALA ALA B . n 
B 1 19  PHE 19  233 233 PHE PHE B . n 
B 1 20  MET 20  234 234 MET MET B . n 
B 1 21  GLU 21  235 235 GLU GLU B . n 
B 1 22  VAL 22  236 236 VAL VAL B . n 
B 1 23  GLN 23  237 237 GLN GLN B . n 
B 1 24  ARG 24  238 238 ARG ARG B . n 
B 1 25  ASP 25  239 239 ASP ASP B . n 
B 1 26  PRO 26  240 240 PRO PRO B . n 
B 1 27  ASP 27  241 241 ASP ASP B . n 
B 1 28  THR 28  242 242 THR THR B . n 
B 1 29  TYR 29  243 243 TYR TYR B . n 
B 1 30  SER 30  244 244 SER SER B . n 
B 1 31  LYS 31  245 245 LYS LYS B . n 
B 1 32  HIS 32  246 246 HIS HIS B . n 
B 1 33  LEU 33  247 247 LEU LEU B . n 
B 1 34  PHE 34  248 248 PHE PHE B . n 
B 1 35  VAL 35  249 249 VAL VAL B . n 
B 1 36  HIS 36  250 250 HIS HIS B . n 
B 1 37  ILE 37  251 251 ILE ILE B . n 
B 1 38  GLY 38  252 252 GLY GLY B . n 
B 1 39  GLN 39  253 253 GLN GLN B . n 
B 1 40  THR 40  254 254 THR THR B . n 
B 1 41  ASN 41  255 255 ASN ASN B . n 
B 1 42  PRO 42  256 256 PRO PRO B . n 
B 1 43  ALA 43  257 257 ALA ALA B . n 
B 1 44  PHE 44  258 258 PHE PHE B . n 
B 1 45  SER 45  259 259 SER SER B . n 
B 1 46  ASP 46  260 260 ASP ASP B . n 
B 1 47  PRO 47  261 261 PRO PRO B . n 
B 1 48  PRO 48  262 262 PRO PRO B . n 
B 1 49  LEU 49  263 263 LEU LEU B . n 
B 1 50  GLU 50  264 264 GLU GLU B . n 
B 1 51  ALA 51  265 265 ALA ALA B . n 
B 1 52  VAL 52  266 266 VAL VAL B . n 
B 1 53  ASP 53  267 267 ASP ASP B . n 
B 1 54  VAL 54  268 268 VAL VAL B . n 
B 1 55  ARG 55  269 269 ARG ARG B . n 
B 1 56  GLN 56  270 270 GLN GLN B . n 
B 1 57  ILE 57  271 271 ILE ILE B . n 
B 1 58  TYR 58  272 272 TYR TYR B . n 
B 1 59  ASP 59  273 273 ASP ASP B . n 
B 1 60  LYS 60  274 274 LYS LYS B . n 
B 1 61  PHE 61  275 275 PHE PHE B . n 
B 1 62  PRO 62  276 276 PRO PRO B . n 
B 1 63  GLU 63  277 277 GLU GLU B . n 
B 1 64  LYS 64  278 278 LYS LYS B . n 
B 1 65  LYS 65  279 279 LYS LYS B . n 
B 1 66  GLY 66  280 280 GLY GLY B . n 
B 1 67  GLY 67  281 281 GLY GLY B . n 
B 1 68  LEU 68  282 282 LEU LEU B . n 
B 1 69  LYS 69  283 283 LYS LYS B . n 
B 1 70  GLU 70  284 284 GLU GLU B . n 
B 1 71  LEU 71  285 285 LEU LEU B . n 
B 1 72  TYR 72  286 286 TYR TYR B . n 
B 1 73  GLU 73  287 287 GLU GLU B . n 
B 1 74  LYS 74  288 288 LYS LYS B . n 
B 1 75  GLY 75  289 289 GLY GLY B . n 
B 1 76  PRO 76  290 290 PRO PRO B . n 
B 1 77  PRO 77  291 291 PRO PRO B . n 
B 1 78  ASN 78  292 292 ASN ASN B . n 
B 1 79  ALA 79  293 293 ALA ALA B . n 
B 1 80  PHE 80  294 294 PHE PHE B . n 
B 1 81  PHE 81  295 295 PHE PHE B . n 
B 1 82  LEU 82  296 296 LEU LEU B . n 
B 1 83  VAL 83  297 297 VAL VAL B . n 
B 1 84  LYS 84  298 298 LYS LYS B . n 
B 1 85  PHE 85  299 299 PHE PHE B . n 
B 1 86  TRP 86  300 300 TRP TRP B . n 
B 1 87  ALA 87  301 301 ALA ALA B . n 
B 1 88  ASP 88  302 302 ASP ASP B . n 
B 1 89  LEU 89  303 303 LEU LEU B . n 
B 1 90  ASN 90  304 304 ASN ASN B . n 
B 1 91  SER 91  305 305 SER SER B . n 
B 1 92  THR 92  306 306 THR THR B . n 
B 1 93  ILE 93  307 307 ILE ILE B . n 
B 1 94  GLN 94  308 308 GLN GLN B . n 
B 1 95  GLU 95  309 309 GLU GLU B . n 
B 1 96  GLY 96  310 310 GLY GLY B . n 
B 1 97  PRO 97  311 311 PRO PRO B . n 
B 1 98  GLY 98  312 312 GLY GLY B . n 
B 1 99  ALA 99  313 313 ALA ALA B . n 
B 1 100 PHE 100 314 314 PHE PHE B . n 
B 1 101 TYR 101 315 315 TYR TYR B . n 
B 1 102 GLY 102 316 316 GLY GLY B . n 
B 1 103 VAL 103 317 317 VAL VAL B . n 
B 1 104 SER 104 318 318 SER SER B . n 
B 1 105 SER 105 319 319 SER SER B . n 
B 1 106 GLN 106 320 320 GLN GLN B . n 
B 1 107 TYR 107 321 321 TYR TYR B . n 
B 1 108 SER 108 322 322 SER SER B . n 
B 1 109 SER 109 323 323 SER SER B . n 
B 1 110 ALA 110 324 324 ALA ALA B . n 
B 1 111 ASP 111 325 325 ASP ASP B . n 
B 1 112 SER 112 326 326 SER SER B . n 
B 1 113 MET 113 327 327 MET MET B . n 
B 1 114 THR 114 328 328 THR THR B . n 
B 1 115 ILE 115 329 329 ILE ILE B . n 
B 1 116 SER 116 330 330 SER SER B . n 
B 1 117 VAL 117 331 331 VAL VAL B . n 
B 1 118 SER 118 332 332 SER SER B . n 
B 1 119 THR 119 333 333 THR THR B . n 
B 1 120 LYS 120 334 334 LYS LYS B . n 
B 1 121 VAL 121 335 335 VAL VAL B . n 
B 1 122 CYS 122 336 336 CYS CYS B . n 
B 1 123 SER 123 337 337 SER SER B . n 
B 1 124 PHE 124 338 338 PHE PHE B . n 
B 1 125 GLY 125 339 339 GLY GLY B . n 
B 1 126 LYS 126 340 340 LYS LYS B . n 
B 1 127 GLN 127 341 341 GLN GLN B . n 
B 1 128 VAL 128 342 342 VAL VAL B . n 
B 1 129 VAL 129 343 343 VAL VAL B . n 
B 1 130 GLU 130 344 344 GLU GLU B . n 
B 1 131 LYS 131 345 345 LYS LYS B . n 
B 1 132 VAL 132 346 346 VAL VAL B . n 
B 1 133 GLU 133 347 347 GLU GLU B . n 
B 1 134 THR 134 348 348 THR THR B . n 
B 1 135 GLU 135 349 349 GLU GLU B . n 
B 1 136 TYR 136 350 350 TYR TYR B . n 
B 1 137 ALA 137 351 351 ALA ALA B . n 
B 1 138 ARG 138 352 352 ARG ARG B . n 
B 1 139 LEU 139 353 353 LEU LEU B . n 
B 1 140 GLU 140 354 354 GLU GLU B . n 
B 1 141 ASN 141 355 355 ASN ASN B . n 
B 1 142 GLY 142 356 356 GLY GLY B . n 
B 1 143 ARG 143 357 357 ARG ARG B . n 
B 1 144 PHE 144 358 358 PHE PHE B . n 
B 1 145 VAL 145 359 359 VAL VAL B . n 
B 1 146 TYR 146 360 360 TYR TYR B . n 
B 1 147 ARG 147 361 361 ARG ARG B . n 
B 1 148 ILE 148 362 362 ILE ILE B . n 
B 1 149 HIS 149 363 363 HIS HIS B . n 
B 1 150 ARG 150 364 364 ARG ARG B . n 
B 1 151 SER 151 365 365 SER SER B . n 
B 1 152 PRO 152 366 366 PRO PRO B . n 
B 1 153 MET 153 367 367 MET MET B . n 
B 1 154 CYS 154 368 368 CYS CYS B . n 
B 1 155 GLU 155 369 369 GLU GLU B . n 
B 1 156 TYR 156 370 370 TYR TYR B . n 
B 1 157 MET 157 371 371 MET MET B . n 
B 1 158 ILE 158 372 372 ILE ILE B . n 
B 1 159 ASN 159 373 373 ASN ASN B . n 
B 1 160 PHE 160 374 374 PHE PHE B . n 
B 1 161 ILE 161 375 375 ILE ILE B . n 
B 1 162 HIS 162 376 376 HIS HIS B . n 
B 1 163 LYS 163 377 377 LYS LYS B . n 
B 1 164 LEU 164 378 378 LEU LEU B . n 
B 1 165 LYS 165 379 379 LYS LYS B . n 
B 1 166 HIS 166 380 380 HIS HIS B . n 
B 1 167 LEU 167 381 381 LEU LEU B . n 
B 1 168 PRO 168 382 382 PRO PRO B . n 
B 1 169 GLU 169 383 383 GLU GLU B . n 
B 1 170 LYS 170 384 384 LYS LYS B . n 
B 1 171 TYR 171 385 385 TYR TYR B . n 
B 1 172 MET 172 386 386 MET MET B . n 
B 1 173 MET 173 387 387 MET MET B . n 
B 1 174 ASN 174 388 388 ASN ASN B . n 
B 1 175 SER 175 389 389 SER SER B . n 
B 1 176 VAL 176 390 390 VAL VAL B . n 
B 1 177 LEU 177 391 391 LEU LEU B . n 
B 1 178 GLU 178 392 392 GLU GLU B . n 
B 1 179 ASN 179 393 393 ASN ASN B . n 
B 1 180 PHE 180 394 394 PHE PHE B . n 
B 1 181 THR 181 395 395 THR THR B . n 
B 1 182 ILE 182 396 396 ILE ILE B . n 
B 1 183 LEU 183 397 397 LEU LEU B . n 
B 1 184 GLN 184 398 398 GLN GLN B . n 
B 1 185 VAL 185 399 399 VAL VAL B . n 
B 1 186 VAL 186 400 400 VAL VAL B . n 
B 1 187 THR 187 401 401 THR THR B . n 
B 1 188 SER 188 402 402 SER SER B . n 
B 1 189 ARG 189 403 403 ARG ARG B . n 
B 1 190 ASP 190 404 404 ASP ASP B . n 
B 1 191 SER 191 405 405 SER SER B . n 
B 1 192 GLN 192 406 406 GLN GLN B . n 
B 1 193 GLU 193 407 407 GLU GLU B . n 
B 1 194 THR 194 408 408 THR THR B . n 
B 1 195 LEU 195 409 409 LEU LEU B . n 
B 1 196 LEU 196 410 410 LEU LEU B . n 
B 1 197 VAL 197 411 411 VAL VAL B . n 
B 1 198 ILE 198 412 412 ILE ILE B . n 
B 1 199 ALA 199 413 413 ALA ALA B . n 
B 1 200 PHE 200 414 414 PHE PHE B . n 
B 1 201 VAL 201 415 415 VAL VAL B . n 
B 1 202 PHE 202 416 416 PHE PHE B . n 
B 1 203 GLU 203 417 417 GLU GLU B . n 
B 1 204 VAL 204 418 418 VAL VAL B . n 
B 1 205 SER 205 419 419 SER SER B . n 
B 1 206 THR 206 420 420 THR THR B . n 
B 1 207 SER 207 421 421 SER SER B . n 
B 1 208 GLU 208 422 422 GLU GLU B . n 
B 1 209 HIS 209 423 423 HIS HIS B . n 
B 1 210 GLY 210 424 424 GLY GLY B . n 
B 1 211 ALA 211 425 425 ALA ALA B . n 
B 1 212 GLN 212 426 426 GLN GLN B . n 
B 1 213 HIS 213 427 427 HIS HIS B . n 
B 1 214 HIS 214 428 428 HIS HIS B . n 
B 1 215 VAL 215 429 429 VAL VAL B . n 
B 1 216 TYR 216 430 430 TYR TYR B . n 
B 1 217 LYS 217 431 431 LYS LYS B . n 
B 1 218 LEU 218 432 432 LEU LEU B . n 
B 1 219 VAL 219 433 433 VAL VAL B . n 
B 1 220 LYS 220 434 434 LYS LYS B . n 
B 1 221 ASP 221 435 435 ASP ASP B . n 
C 1 1   SER 1   215 215 SER SER C . n 
C 1 2   GLN 2   216 216 GLN GLN C . n 
C 1 3   ASP 3   217 217 ASP ASP C . n 
C 1 4   ARG 4   218 218 ARG ARG C . n 
C 1 5   THR 5   219 219 THR THR C . n 
C 1 6   ILE 6   220 220 ILE ILE C . n 
C 1 7   ALA 7   221 221 ALA ALA C . n 
C 1 8   SER 8   222 222 SER SER C . n 
C 1 9   SER 9   223 223 SER SER C . n 
C 1 10  ARG 10  224 224 ARG ARG C . n 
C 1 11  LEU 11  225 225 LEU LEU C . n 
C 1 12  ARG 12  226 226 ARG ARG C . n 
C 1 13  LEU 13  227 227 LEU LEU C . n 
C 1 14  LEU 14  228 228 LEU LEU C . n 
C 1 15  GLU 15  229 229 GLU GLU C . n 
C 1 16  TYR 16  230 230 TYR TYR C . n 
C 1 17  SER 17  231 231 SER SER C . n 
C 1 18  ALA 18  232 232 ALA ALA C . n 
C 1 19  PHE 19  233 233 PHE PHE C . n 
C 1 20  MET 20  234 234 MET MET C . n 
C 1 21  GLU 21  235 235 GLU GLU C . n 
C 1 22  VAL 22  236 236 VAL VAL C . n 
C 1 23  GLN 23  237 237 GLN GLN C . n 
C 1 24  ARG 24  238 238 ARG ARG C . n 
C 1 25  ASP 25  239 239 ASP ASP C . n 
C 1 26  PRO 26  240 240 PRO PRO C . n 
C 1 27  ASP 27  241 241 ASP ASP C . n 
C 1 28  THR 28  242 242 THR THR C . n 
C 1 29  TYR 29  243 243 TYR TYR C . n 
C 1 30  SER 30  244 244 SER SER C . n 
C 1 31  LYS 31  245 245 LYS LYS C . n 
C 1 32  HIS 32  246 246 HIS HIS C . n 
C 1 33  LEU 33  247 247 LEU LEU C . n 
C 1 34  PHE 34  248 248 PHE PHE C . n 
C 1 35  VAL 35  249 249 VAL VAL C . n 
C 1 36  HIS 36  250 250 HIS HIS C . n 
C 1 37  ILE 37  251 251 ILE ILE C . n 
C 1 38  GLY 38  252 252 GLY GLY C . n 
C 1 39  GLN 39  253 253 GLN GLN C . n 
C 1 40  THR 40  254 254 THR THR C . n 
C 1 41  ASN 41  255 255 ASN ASN C . n 
C 1 42  PRO 42  256 256 PRO PRO C . n 
C 1 43  ALA 43  257 257 ALA ALA C . n 
C 1 44  PHE 44  258 258 PHE PHE C . n 
C 1 45  SER 45  259 259 SER SER C . n 
C 1 46  ASP 46  260 260 ASP ASP C . n 
C 1 47  PRO 47  261 261 PRO PRO C . n 
C 1 48  PRO 48  262 262 PRO PRO C . n 
C 1 49  LEU 49  263 263 LEU LEU C . n 
C 1 50  GLU 50  264 264 GLU GLU C . n 
C 1 51  ALA 51  265 265 ALA ALA C . n 
C 1 52  VAL 52  266 266 VAL VAL C . n 
C 1 53  ASP 53  267 267 ASP ASP C . n 
C 1 54  VAL 54  268 268 VAL VAL C . n 
C 1 55  ARG 55  269 269 ARG ARG C . n 
C 1 56  GLN 56  270 270 GLN GLN C . n 
C 1 57  ILE 57  271 271 ILE ILE C . n 
C 1 58  TYR 58  272 272 TYR TYR C . n 
C 1 59  ASP 59  273 273 ASP ASP C . n 
C 1 60  LYS 60  274 274 LYS LYS C . n 
C 1 61  PHE 61  275 275 PHE PHE C . n 
C 1 62  PRO 62  276 276 PRO PRO C . n 
C 1 63  GLU 63  277 277 GLU GLU C . n 
C 1 64  LYS 64  278 278 LYS LYS C . n 
C 1 65  LYS 65  279 279 LYS LYS C . n 
C 1 66  GLY 66  280 280 GLY GLY C . n 
C 1 67  GLY 67  281 281 GLY GLY C . n 
C 1 68  LEU 68  282 282 LEU LEU C . n 
C 1 69  LYS 69  283 283 LYS LYS C . n 
C 1 70  GLU 70  284 284 GLU GLU C . n 
C 1 71  LEU 71  285 285 LEU LEU C . n 
C 1 72  TYR 72  286 286 TYR TYR C . n 
C 1 73  GLU 73  287 287 GLU GLU C . n 
C 1 74  LYS 74  288 288 LYS LYS C . n 
C 1 75  GLY 75  289 289 GLY GLY C . n 
C 1 76  PRO 76  290 290 PRO PRO C . n 
C 1 77  PRO 77  291 291 PRO PRO C . n 
C 1 78  ASN 78  292 292 ASN ASN C . n 
C 1 79  ALA 79  293 293 ALA ALA C . n 
C 1 80  PHE 80  294 294 PHE PHE C . n 
C 1 81  PHE 81  295 295 PHE PHE C . n 
C 1 82  LEU 82  296 296 LEU LEU C . n 
C 1 83  VAL 83  297 297 VAL VAL C . n 
C 1 84  LYS 84  298 298 LYS LYS C . n 
C 1 85  PHE 85  299 299 PHE PHE C . n 
C 1 86  TRP 86  300 300 TRP TRP C . n 
C 1 87  ALA 87  301 301 ALA ALA C . n 
C 1 88  ASP 88  302 302 ASP ASP C . n 
C 1 89  LEU 89  303 303 LEU LEU C . n 
C 1 90  ASN 90  304 304 ASN ASN C . n 
C 1 91  SER 91  305 305 SER SER C . n 
C 1 92  THR 92  306 306 THR THR C . n 
C 1 93  ILE 93  307 307 ILE ILE C . n 
C 1 94  GLN 94  308 308 GLN GLN C . n 
C 1 95  GLU 95  309 309 GLU GLU C . n 
C 1 96  GLY 96  310 310 GLY GLY C . n 
C 1 97  PRO 97  311 311 PRO PRO C . n 
C 1 98  GLY 98  312 312 GLY GLY C . n 
C 1 99  ALA 99  313 313 ALA ALA C . n 
C 1 100 PHE 100 314 314 PHE PHE C . n 
C 1 101 TYR 101 315 315 TYR TYR C . n 
C 1 102 GLY 102 316 316 GLY GLY C . n 
C 1 103 VAL 103 317 317 VAL VAL C . n 
C 1 104 SER 104 318 318 SER SER C . n 
C 1 105 SER 105 319 319 SER SER C . n 
C 1 106 GLN 106 320 320 GLN GLN C . n 
C 1 107 TYR 107 321 321 TYR TYR C . n 
C 1 108 SER 108 322 322 SER SER C . n 
C 1 109 SER 109 323 323 SER SER C . n 
C 1 110 ALA 110 324 324 ALA ALA C . n 
C 1 111 ASP 111 325 325 ASP ASP C . n 
C 1 112 SER 112 326 326 SER SER C . n 
C 1 113 MET 113 327 327 MET MET C . n 
C 1 114 THR 114 328 328 THR THR C . n 
C 1 115 ILE 115 329 329 ILE ILE C . n 
C 1 116 SER 116 330 330 SER SER C . n 
C 1 117 VAL 117 331 331 VAL VAL C . n 
C 1 118 SER 118 332 332 SER SER C . n 
C 1 119 THR 119 333 333 THR THR C . n 
C 1 120 LYS 120 334 334 LYS LYS C . n 
C 1 121 VAL 121 335 335 VAL VAL C . n 
C 1 122 CYS 122 336 336 CYS CYS C . n 
C 1 123 SER 123 337 337 SER SER C . n 
C 1 124 PHE 124 338 338 PHE PHE C . n 
C 1 125 GLY 125 339 339 GLY GLY C . n 
C 1 126 LYS 126 340 340 LYS LYS C . n 
C 1 127 GLN 127 341 341 GLN GLN C . n 
C 1 128 VAL 128 342 342 VAL VAL C . n 
C 1 129 VAL 129 343 343 VAL VAL C . n 
C 1 130 GLU 130 344 344 GLU GLU C . n 
C 1 131 LYS 131 345 345 LYS LYS C . n 
C 1 132 VAL 132 346 346 VAL VAL C . n 
C 1 133 GLU 133 347 347 GLU GLU C . n 
C 1 134 THR 134 348 348 THR THR C . n 
C 1 135 GLU 135 349 349 GLU GLU C . n 
C 1 136 TYR 136 350 350 TYR TYR C . n 
C 1 137 ALA 137 351 351 ALA ALA C . n 
C 1 138 ARG 138 352 352 ARG ARG C . n 
C 1 139 LEU 139 353 353 LEU LEU C . n 
C 1 140 GLU 140 354 354 GLU GLU C . n 
C 1 141 ASN 141 355 355 ASN ASN C . n 
C 1 142 GLY 142 356 356 GLY GLY C . n 
C 1 143 ARG 143 357 357 ARG ARG C . n 
C 1 144 PHE 144 358 358 PHE PHE C . n 
C 1 145 VAL 145 359 359 VAL VAL C . n 
C 1 146 TYR 146 360 360 TYR TYR C . n 
C 1 147 ARG 147 361 361 ARG ARG C . n 
C 1 148 ILE 148 362 362 ILE ILE C . n 
C 1 149 HIS 149 363 363 HIS HIS C . n 
C 1 150 ARG 150 364 364 ARG ARG C . n 
C 1 151 SER 151 365 365 SER SER C . n 
C 1 152 PRO 152 366 366 PRO PRO C . n 
C 1 153 MET 153 367 367 MET MET C . n 
C 1 154 CYS 154 368 368 CYS CYS C . n 
C 1 155 GLU 155 369 369 GLU GLU C . n 
C 1 156 TYR 156 370 370 TYR TYR C . n 
C 1 157 MET 157 371 371 MET MET C . n 
C 1 158 ILE 158 372 372 ILE ILE C . n 
C 1 159 ASN 159 373 373 ASN ASN C . n 
C 1 160 PHE 160 374 374 PHE PHE C . n 
C 1 161 ILE 161 375 375 ILE ILE C . n 
C 1 162 HIS 162 376 376 HIS HIS C . n 
C 1 163 LYS 163 377 377 LYS LYS C . n 
C 1 164 LEU 164 378 378 LEU LEU C . n 
C 1 165 LYS 165 379 379 LYS LYS C . n 
C 1 166 HIS 166 380 380 HIS HIS C . n 
C 1 167 LEU 167 381 381 LEU LEU C . n 
C 1 168 PRO 168 382 382 PRO PRO C . n 
C 1 169 GLU 169 383 383 GLU GLU C . n 
C 1 170 LYS 170 384 384 LYS LYS C . n 
C 1 171 TYR 171 385 385 TYR TYR C . n 
C 1 172 MET 172 386 386 MET MET C . n 
C 1 173 MET 173 387 387 MET MET C . n 
C 1 174 ASN 174 388 388 ASN ASN C . n 
C 1 175 SER 175 389 389 SER SER C . n 
C 1 176 VAL 176 390 390 VAL VAL C . n 
C 1 177 LEU 177 391 391 LEU LEU C . n 
C 1 178 GLU 178 392 392 GLU GLU C . n 
C 1 179 ASN 179 393 393 ASN ASN C . n 
C 1 180 PHE 180 394 394 PHE PHE C . n 
C 1 181 THR 181 395 395 THR THR C . n 
C 1 182 ILE 182 396 396 ILE ILE C . n 
C 1 183 LEU 183 397 397 LEU LEU C . n 
C 1 184 GLN 184 398 398 GLN GLN C . n 
C 1 185 VAL 185 399 399 VAL VAL C . n 
C 1 186 VAL 186 400 400 VAL VAL C . n 
C 1 187 THR 187 401 401 THR THR C . n 
C 1 188 SER 188 402 402 SER SER C . n 
C 1 189 ARG 189 403 403 ARG ARG C . n 
C 1 190 ASP 190 404 404 ASP ASP C . n 
C 1 191 SER 191 405 405 SER SER C . n 
C 1 192 GLN 192 406 406 GLN GLN C . n 
C 1 193 GLU 193 407 407 GLU GLU C . n 
C 1 194 THR 194 408 408 THR THR C . n 
C 1 195 LEU 195 409 409 LEU LEU C . n 
C 1 196 LEU 196 410 410 LEU LEU C . n 
C 1 197 VAL 197 411 411 VAL VAL C . n 
C 1 198 ILE 198 412 412 ILE ILE C . n 
C 1 199 ALA 199 413 413 ALA ALA C . n 
C 1 200 PHE 200 414 414 PHE PHE C . n 
C 1 201 VAL 201 415 415 VAL VAL C . n 
C 1 202 PHE 202 416 416 PHE PHE C . n 
C 1 203 GLU 203 417 417 GLU GLU C . n 
C 1 204 VAL 204 418 418 VAL VAL C . n 
C 1 205 SER 205 419 419 SER SER C . n 
C 1 206 THR 206 420 420 THR THR C . n 
C 1 207 SER 207 421 421 SER SER C . n 
C 1 208 GLU 208 422 422 GLU GLU C . n 
C 1 209 HIS 209 423 423 HIS HIS C . n 
C 1 210 GLY 210 424 424 GLY GLY C . n 
C 1 211 ALA 211 425 425 ALA ALA C . n 
C 1 212 GLN 212 426 426 GLN GLN C . n 
C 1 213 HIS 213 427 427 HIS HIS C . n 
C 1 214 HIS 214 428 428 HIS HIS C . n 
C 1 215 VAL 215 429 429 VAL VAL C . n 
C 1 216 TYR 216 430 430 TYR TYR C . n 
C 1 217 LYS 217 431 431 LYS LYS C . n 
C 1 218 LEU 218 432 432 LEU LEU C . n 
C 1 219 VAL 219 433 433 VAL VAL C . n 
C 1 220 LYS 220 434 434 LYS LYS C . n 
C 1 221 ASP 221 435 435 ASP ASP C . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        A1L1N 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   A1L1N 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
D 2 A1L1N 1  501 501 A1L1N LIG A . 
E 2 A1L1N 1  501 501 A1L1N LIG B . 
F 2 A1L1N 1  501 501 A1L1N LIG C . 
G 3 HOH   1  601 16  HOH   HOH A . 
G 3 HOH   2  602 23  HOH   HOH A . 
G 3 HOH   3  603 8   HOH   HOH A . 
G 3 HOH   4  604 26  HOH   HOH A . 
G 3 HOH   5  605 36  HOH   HOH A . 
G 3 HOH   6  606 30  HOH   HOH A . 
G 3 HOH   7  607 32  HOH   HOH A . 
H 3 HOH   1  601 31  HOH   HOH B . 
H 3 HOH   2  602 11  HOH   HOH B . 
H 3 HOH   3  603 12  HOH   HOH B . 
H 3 HOH   4  604 4   HOH   HOH B . 
H 3 HOH   5  605 19  HOH   HOH B . 
H 3 HOH   6  606 25  HOH   HOH B . 
H 3 HOH   7  607 15  HOH   HOH B . 
H 3 HOH   8  608 18  HOH   HOH B . 
H 3 HOH   9  609 22  HOH   HOH B . 
H 3 HOH   10 610 7   HOH   HOH B . 
H 3 HOH   11 611 17  HOH   HOH B . 
H 3 HOH   12 612 34  HOH   HOH B . 
H 3 HOH   13 613 5   HOH   HOH B . 
H 3 HOH   14 614 24  HOH   HOH B . 
H 3 HOH   15 615 9   HOH   HOH B . 
I 3 HOH   1  601 20  HOH   HOH C . 
I 3 HOH   2  602 6   HOH   HOH C . 
I 3 HOH   3  603 35  HOH   HOH C . 
I 3 HOH   4  604 28  HOH   HOH C . 
I 3 HOH   5  605 3   HOH   HOH C . 
I 3 HOH   6  606 1   HOH   HOH C . 
I 3 HOH   7  607 14  HOH   HOH C . 
I 3 HOH   8  608 33  HOH   HOH C . 
I 3 HOH   9  609 21  HOH   HOH C . 
I 3 HOH   10 610 10  HOH   HOH C . 
I 3 HOH   11 611 13  HOH   HOH C . 
I 3 HOH   12 612 29  HOH   HOH C . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX ? ? ? 1.20.1_4487 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS    ? ? ? .           2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? XDS    ? ? ? .           3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER ? ? ? .           4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8ZBG 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     46.230 
_cell.length_a_esd                 ? 
_cell.length_b                     101.160 
_cell.length_b_esd                 ? 
_cell.length_c                     148.850 
_cell.length_c_esd                 ? 
_cell.volume                       696115.899 
_cell.volume_esd                   ? 
_cell.Z_PDB                        12 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8ZBG 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                19 
_symmetry.space_group_name_Hall            'P 2ac 2ab' 
_symmetry.space_group_name_H-M             'P 21 21 21' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8ZBG 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.28 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          46.15 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, HANGING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '0.1M HEPES pH 7.5, 0.2M Ammonium acetate, 18% PEG 3350' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            300 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     CCD 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'ADSC QUANTUM 315r' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2022-05-03 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.97 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'PAL/PLS BEAMLINE 5C (4A)' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.97 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   '5C (4A)' 
_diffrn_source.pdbx_synchrotron_site       PAL/PLS 
# 
_reflns.B_iso_Wilson_estimate                          55.31 
_reflns.entry_id                                       8ZBG 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.67 
_reflns.d_resolution_low                               28.99 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     20559 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           99.77 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                2 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          14.09 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.999 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.03474 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.67 
_reflns_shell.d_res_low                                     2.765 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           2.15 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             2018 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.838 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  0.3278 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               60.10 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8ZBG 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.67 
_refine.ls_d_res_low                             28.99 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     20548 
_refine.ls_number_reflns_R_free                  1028 
_refine.ls_number_reflns_R_work                  19520 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.89 
_refine.ls_percent_reflns_R_free                 5.00 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.2160 
_refine.ls_R_factor_R_free                       0.2610 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.2136 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.35 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1000 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 29.7460 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.3988 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.67 
_refine_hist.d_res_low                        28.99 
_refine_hist.number_atoms_solvent             34 
_refine_hist.number_atoms_total               5458 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        5349 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         75 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0099  ? 5562 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 1.3346  ? 7528 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0652  ? 808  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0092  ? 960  ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 16.5202 ? 2055 ? f_dihedral_angle_d ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 2.67 2.81  . . 144 2737 99.86  . . . . 0.2910 . . . . . . . . . . . 0.3759 
'X-RAY DIFFRACTION' 2.81 2.99  . . 143 2722 99.86  . . . . 0.2635 . . . . . . . . . . . 0.3671 
'X-RAY DIFFRACTION' 2.99 3.22  . . 145 2748 99.93  . . . . 0.2617 . . . . . . . . . . . 0.3457 
'X-RAY DIFFRACTION' 3.22 3.54  . . 146 2774 99.86  . . . . 0.2289 . . . . . . . . . . . 0.2954 
'X-RAY DIFFRACTION' 3.54 4.05  . . 146 2773 100.00 . . . . 0.2034 . . . . . . . . . . . 0.2462 
'X-RAY DIFFRACTION' 4.05 5.10  . . 148 2816 99.97  . . . . 0.1763 . . . . . . . . . . . 0.1899 
'X-RAY DIFFRACTION' 5.10 28.99 . . 156 2950 99.74  . . . . 0.2052 . . . . . . . . . . . 0.2484 
# 
_struct.entry_id                     8ZBG 
_struct.title                        'Crystal structure of TEAD3 YAP binding domain with compound 15' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8ZBG 
_struct_keywords.text            'transcription factor, TEAD3, TRANSCRIPTION' 
_struct_keywords.pdbx_keywords   TRANSCRIPTION 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 1 ? 
D N N 2 ? 
E N N 2 ? 
F N N 2 ? 
G N N 3 ? 
H N N 3 ? 
I N N 3 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    TEAD3_HUMAN 
_struct_ref.pdbx_db_accession          Q99594 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;QDRTIASSRLRLLEYSAFMEVQRDPDTYSKHLFVHIGQTNPAFSDPPLEAVDVRQIYDKFPEKKGGLKELYEKGPPNAFF
LVKFWADLNSTIQEGPGAFYGVSSQYSSADSMTISVSTKVCSFGKQVVEKVETEYARLENGRFVYRIHRSPMCEYMINFI
HKLKHLPEKYMMNSVLENFTILQVVTSRDSQETLLVIAFVFEVSTSEHGAQHHVYKLVKD
;
_struct_ref.pdbx_align_begin           216 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8ZBG A 2 ? 221 ? Q99594 216 ? 435 ? 216 435 
2 1 8ZBG B 2 ? 221 ? Q99594 216 ? 435 ? 216 435 
3 1 8ZBG C 2 ? 221 ? Q99594 216 ? 435 ? 216 435 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8ZBG SER A 1 ? UNP Q99594 ? ? 'expression tag' 215 1 
2 8ZBG SER B 1 ? UNP Q99594 ? ? 'expression tag' 215 2 
3 8ZBG SER C 1 ? UNP Q99594 ? ? 'expression tag' 215 3 
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 author_defined_assembly ? monomeric 1 
2 author_defined_assembly ? monomeric 1 
3 author_defined_assembly ? monomeric 1 
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 1 A,D,G 
2 1 B,E,H 
3 1 C,F,I 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 VAL A 54  ? TYR A 58  ? VAL A 268 TYR A 272 1 ? 5  
HELX_P HELX_P2  AA2 ASP A 59  ? PHE A 61  ? ASP A 273 PHE A 275 5 ? 3  
HELX_P HELX_P3  AA3 GLY A 67  ? GLY A 75  ? GLY A 281 GLY A 289 1 ? 9  
HELX_P HELX_P4  AA4 PRO A 76  ? ASN A 78  ? PRO A 290 ASN A 292 5 ? 3  
HELX_P HELX_P5  AA5 CYS A 154 ? LEU A 167 ? CYS A 368 LEU A 381 1 ? 14 
HELX_P HELX_P6  AA6 GLU A 169 ? GLU A 178 ? GLU A 383 GLU A 392 1 ? 10 
HELX_P HELX_P7  AA7 ARG B 55  ? PHE B 61  ? ARG B 269 PHE B 275 5 ? 7  
HELX_P HELX_P8  AA8 GLY B 67  ? GLY B 75  ? GLY B 281 GLY B 289 1 ? 9  
HELX_P HELX_P9  AA9 PRO B 76  ? ASN B 78  ? PRO B 290 ASN B 292 5 ? 3  
HELX_P HELX_P10 AB1 CYS B 154 ? LEU B 167 ? CYS B 368 LEU B 381 1 ? 14 
HELX_P HELX_P11 AB2 GLU B 169 ? ASN B 179 ? GLU B 383 ASN B 393 1 ? 11 
HELX_P HELX_P12 AB3 ARG C 55  ? TYR C 58  ? ARG C 269 TYR C 272 5 ? 4  
HELX_P HELX_P13 AB4 GLY C 67  ? GLY C 75  ? GLY C 281 GLY C 289 1 ? 9  
HELX_P HELX_P14 AB5 PRO C 76  ? ASN C 78  ? PRO C 290 ASN C 292 5 ? 3  
HELX_P HELX_P15 AB6 CYS C 154 ? LEU C 167 ? CYS C 368 LEU C 381 1 ? 14 
HELX_P HELX_P16 AB7 GLU C 169 ? ASN C 179 ? GLU C 383 ASN C 393 1 ? 11 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 GLY 75 A . ? GLY 289 A PRO 76 A ? PRO 290 A 1 -6.86 
2 GLY 75 B . ? GLY 289 B PRO 76 B ? PRO 290 B 1 -2.24 
3 GLY 75 C . ? GLY 289 C PRO 76 C ? PRO 290 C 1 -3.91 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 8  ? 
AA2 ? 10 ? 
AA3 ? 7  ? 
AA4 ? 14 ? 
AA5 ? 3  ? 
AA6 ? 5  ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1  2  ? anti-parallel 
AA1 2  3  ? anti-parallel 
AA1 3  4  ? anti-parallel 
AA1 4  5  ? anti-parallel 
AA1 5  6  ? anti-parallel 
AA1 6  7  ? anti-parallel 
AA1 7  8  ? anti-parallel 
AA2 1  2  ? anti-parallel 
AA2 2  3  ? anti-parallel 
AA2 3  4  ? anti-parallel 
AA2 4  5  ? anti-parallel 
AA2 5  6  ? anti-parallel 
AA2 6  7  ? anti-parallel 
AA2 7  8  ? anti-parallel 
AA2 8  9  ? anti-parallel 
AA2 9  10 ? anti-parallel 
AA3 1  2  ? parallel      
AA3 2  3  ? anti-parallel 
AA3 3  4  ? parallel      
AA3 4  5  ? anti-parallel 
AA3 5  6  ? anti-parallel 
AA3 6  7  ? anti-parallel 
AA4 1  2  ? anti-parallel 
AA4 2  3  ? anti-parallel 
AA4 3  4  ? anti-parallel 
AA4 4  5  ? parallel      
AA4 5  6  ? anti-parallel 
AA4 6  7  ? parallel      
AA4 7  8  ? anti-parallel 
AA4 8  9  ? parallel      
AA4 9  10 ? anti-parallel 
AA4 10 11 ? parallel      
AA4 11 12 ? anti-parallel 
AA4 12 13 ? anti-parallel 
AA4 13 14 ? anti-parallel 
AA5 1  2  ? anti-parallel 
AA5 2  3  ? anti-parallel 
AA6 1  2  ? anti-parallel 
AA6 2  3  ? anti-parallel 
AA6 3  4  ? anti-parallel 
AA6 4  5  ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1  ARG A 138 ? LEU A 139 ? ARG A 352 LEU A 353 
AA1 2  PHE A 144 ? PRO A 152 ? PHE A 358 PRO A 366 
AA1 3  PHE A 100 ? SER A 109 ? PHE A 314 SER A 323 
AA1 4  ARG A 12  ? GLN A 23  ? ARG A 226 GLN A 237 
AA1 5  THR A 28  ? ILE A 37  ? THR A 242 ILE A 251 
AA1 6  THR B 28  ? GLY B 38  ? THR B 242 GLY B 252 
AA1 7  ARG B 12  ? ASP B 25  ? ARG B 226 ASP B 239 
AA1 8  ILE B 6   ? ALA B 7   ? ILE B 220 ALA B 221 
AA2 1  ARG A 138 ? LEU A 139 ? ARG A 352 LEU A 353 
AA2 2  PHE A 144 ? PRO A 152 ? PHE A 358 PRO A 366 
AA2 3  PHE A 100 ? SER A 109 ? PHE A 314 SER A 323 
AA2 4  ARG A 12  ? GLN A 23  ? ARG A 226 GLN A 237 
AA2 5  THR A 28  ? ILE A 37  ? THR A 242 ILE A 251 
AA2 6  THR B 28  ? GLY B 38  ? THR B 242 GLY B 252 
AA2 7  ARG B 12  ? ASP B 25  ? ARG B 226 ASP B 239 
AA2 8  PHE B 100 ? SER B 109 ? PHE B 314 SER B 323 
AA2 9  ARG B 143 ? PRO B 152 ? ARG B 357 PRO B 366 
AA2 10 ARG B 138 ? GLU B 140 ? ARG B 352 GLU B 354 
AA3 1  ALA A 51  ? ASP A 53  ? ALA A 265 ASP A 267 
AA3 2  GLN A 212 ? VAL A 219 ? GLN A 426 VAL A 433 
AA3 3  PHE A 80  ? ALA A 87  ? PHE A 294 ALA A 301 
AA3 4  THR A 194 ? VAL A 204 ? THR A 408 VAL A 418 
AA3 5  PHE A 180 ? SER A 188 ? PHE A 394 SER A 402 
AA3 6  THR A 114 ? SER A 123 ? THR A 328 SER A 337 
AA3 7  LYS A 126 ? TYR A 136 ? LYS A 340 TYR A 350 
AA4 1  LYS B 126 ? TYR B 136 ? LYS B 340 TYR B 350 
AA4 2  THR B 114 ? SER B 123 ? THR B 328 SER B 337 
AA4 3  PHE B 180 ? SER B 188 ? PHE B 394 SER B 402 
AA4 4  THR B 194 ? VAL B 204 ? THR B 408 VAL B 418 
AA4 5  PHE B 80  ? ALA B 87  ? PHE B 294 ALA B 301 
AA4 6  GLN B 212 ? VAL B 219 ? GLN B 426 VAL B 433 
AA4 7  GLU B 50  ? ASP B 53  ? GLU B 264 ASP B 267 
AA4 8  GLU C 50  ? ASP C 53  ? GLU C 264 ASP C 267 
AA4 9  GLN C 212 ? VAL C 219 ? GLN C 426 VAL C 433 
AA4 10 PHE C 80  ? ALA C 87  ? PHE C 294 ALA C 301 
AA4 11 THR C 194 ? VAL C 204 ? THR C 408 VAL C 418 
AA4 12 PHE C 180 ? SER C 188 ? PHE C 394 SER C 402 
AA4 13 ILE C 115 ? SER C 123 ? ILE C 329 SER C 337 
AA4 14 LYS C 126 ? GLU C 135 ? LYS C 340 GLU C 349 
AA5 1  ILE C 6   ? ALA C 7   ? ILE C 220 ALA C 221 
AA5 2  ARG C 12  ? GLN C 23  ? ARG C 226 GLN C 237 
AA5 3  TYR C 29  ? GLY C 38  ? TYR C 243 GLY C 252 
AA6 1  ILE C 6   ? ALA C 7   ? ILE C 220 ALA C 221 
AA6 2  ARG C 12  ? GLN C 23  ? ARG C 226 GLN C 237 
AA6 3  PHE C 100 ? SER C 109 ? PHE C 314 SER C 323 
AA6 4  ARG C 143 ? PRO C 152 ? ARG C 357 PRO C 366 
AA6 5  ARG C 138 ? GLU C 140 ? ARG C 352 GLU C 354 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1  2  N ARG A 138 ? N ARG A 352 O VAL A 145 ? O VAL A 359 
AA1 2  3  O PHE A 144 ? O PHE A 358 N SER A 109 ? N SER A 323 
AA1 3  4  O GLY A 102 ? O GLY A 316 N PHE A 19  ? N PHE A 233 
AA1 4  5  N VAL A 22  ? N VAL A 236 O SER A 30  ? O SER A 244 
AA1 5  6  N TYR A 29  ? N TYR A 243 O TYR B 29  ? O TYR B 243 
AA1 6  7  O PHE B 34  ? O PHE B 248 N ALA B 18  ? N ALA B 232 
AA1 7  8  O LEU B 13  ? O LEU B 227 N ILE B 6   ? N ILE B 220 
AA2 1  2  N ARG A 138 ? N ARG A 352 O VAL A 145 ? O VAL A 359 
AA2 2  3  O PHE A 144 ? O PHE A 358 N SER A 109 ? N SER A 323 
AA2 3  4  O GLY A 102 ? O GLY A 316 N PHE A 19  ? N PHE A 233 
AA2 4  5  N VAL A 22  ? N VAL A 236 O SER A 30  ? O SER A 244 
AA2 5  6  N TYR A 29  ? N TYR A 243 O TYR B 29  ? O TYR B 243 
AA2 6  7  O PHE B 34  ? O PHE B 248 N ALA B 18  ? N ALA B 232 
AA2 7  8  N LEU B 14  ? N LEU B 228 O GLN B 106 ? O GLN B 320 
AA2 8  9  N SER B 109 ? N SER B 323 O PHE B 144 ? O PHE B 358 
AA2 9  10 O VAL B 145 ? O VAL B 359 N ARG B 138 ? N ARG B 352 
AA3 1  2  N VAL A 52  ? N VAL A 266 O LYS A 217 ? O LYS A 431 
AA3 2  3  O TYR A 216 ? O TYR A 430 N LEU A 82  ? N LEU A 296 
AA3 3  4  N PHE A 85  ? N PHE A 299 O VAL A 201 ? O VAL A 415 
AA3 4  5  O PHE A 200 ? O PHE A 414 N ILE A 182 ? N ILE A 396 
AA3 5  6  O LEU A 183 ? O LEU A 397 N LYS A 120 ? N LYS A 334 
AA3 6  7  N VAL A 117 ? N VAL A 331 O GLU A 133 ? O GLU A 347 
AA4 1  2  O VAL B 128 ? O VAL B 342 N VAL B 121 ? N VAL B 335 
AA4 2  3  N CYS B 122 ? N CYS B 336 O THR B 181 ? O THR B 395 
AA4 3  4  N ILE B 182 ? N ILE B 396 O PHE B 200 ? O PHE B 414 
AA4 4  5  O GLU B 203 ? O GLU B 417 N ALA B 87  ? N ALA B 301 
AA4 5  6  N LEU B 82  ? N LEU B 296 O TYR B 216 ? O TYR B 430 
AA4 6  7  O LYS B 217 ? O LYS B 431 N GLU B 50  ? N GLU B 264 
AA4 7  8  N ALA B 51  ? N ALA B 265 O ALA C 51  ? O ALA C 265 
AA4 8  9  N VAL C 52  ? N VAL C 266 O VAL C 219 ? O VAL C 433 
AA4 9  10 O TYR C 216 ? O TYR C 430 N LEU C 82  ? N LEU C 296 
AA4 10 11 N VAL C 83  ? N VAL C 297 O ALA C 199 ? O ALA C 413 
AA4 11 12 O LEU C 195 ? O LEU C 409 N VAL C 186 ? N VAL C 400 
AA4 12 13 O VAL C 185 ? O VAL C 399 N SER C 118 ? N SER C 332 
AA4 13 14 N VAL C 117 ? N VAL C 331 O GLU C 133 ? O GLU C 347 
AA5 1  2  N ILE C 6   ? N ILE C 220 O LEU C 13  ? O LEU C 227 
AA5 2  3  N TYR C 16  ? N TYR C 230 O ILE C 37  ? O ILE C 251 
AA6 1  2  N ILE C 6   ? N ILE C 220 O LEU C 13  ? O LEU C 227 
AA6 2  3  N GLU C 21  ? N GLU C 235 O PHE C 100 ? O PHE C 314 
AA6 3  4  N TYR C 107 ? N TYR C 321 O TYR C 146 ? O TYR C 360 
AA6 4  5  O ARG C 143 ? O ARG C 357 N GLU C 140 ? N GLU C 354 
# 
_pdbx_entry_details.entry_id                   8ZBG 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1 1 N A SER 421 ? ? CA A SER 421 ? ? C  A SER 421 ? ? 93.97  111.00 -17.03 2.70 N 
2 1 C B ASN 255 ? ? N  B PRO 256 ? ? CA B PRO 256 ? ? 109.19 119.30 -10.11 1.50 Y 
3 1 N B PHE 258 ? ? CA B PHE 258 ? ? C  B PHE 258 ? ? 91.80  111.00 -19.20 2.70 N 
4 1 N B GLU 277 ? ? CA B GLU 277 ? ? C  B GLU 277 ? ? 127.31 111.00 16.31  2.70 N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 GLU A 354 ? ? -121.20 -163.03 
2 1 GLN B 216 ? ? -161.20 73.35   
3 1 SER B 222 ? ? -100.86 -164.03 
4 1 LEU B 410 ? ? -170.66 127.20  
5 1 HIS C 250 ? ? -160.25 117.22  
6 1 ASP C 260 ? ? -159.28 63.33   
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z           
2 x+1/2,-y+1/2,-z 
3 -x,y+1/2,-z+1/2 
4 -x+1/2,-y,z+1/2 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1 1 Y 1 A SER 215 ? A SER 1 
2 1 Y 1 A GLN 216 ? A GLN 2 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
A1L1N N1   N N N 1   
A1L1N C4   C Y N 2   
A1L1N C5   C N N 3   
A1L1N C6   C Y N 4   
A1L1N C7   C Y N 5   
A1L1N C8   C Y N 6   
A1L1N C10  C N N 7   
A1L1N C13  C Y N 8   
A1L1N C15  C Y N 9   
A1L1N C17  C Y N 10  
A1L1N C1   C N N 11  
A1L1N C11  C N R 12  
A1L1N C12  C N N 13  
A1L1N C14  C Y N 14  
A1L1N C16  C Y N 15  
A1L1N C18  C Y N 16  
A1L1N C19  C N N 17  
A1L1N C2   C N N 18  
A1L1N C3   C Y N 19  
A1L1N C9   C Y N 20  
A1L1N F1   F N N 21  
A1L1N F2   F N N 22  
A1L1N F3   F N N 23  
A1L1N F4   F N N 24  
A1L1N O1   O N N 25  
A1L1N H52  H N N 26  
A1L1N H51  H N N 27  
A1L1N H61  H N N 28  
A1L1N H81  H N N 29  
A1L1N H151 H N N 30  
A1L1N H171 H N N 31  
A1L1N H11  H N N 32  
A1L1N H12  H N N 33  
A1L1N H111 H N N 34  
A1L1N H122 H N N 35  
A1L1N H123 H N N 36  
A1L1N H121 H N N 37  
A1L1N H141 H N N 38  
A1L1N H181 H N N 39  
A1L1N H23  H N N 40  
A1L1N H22  H N N 41  
A1L1N H91  H N N 42  
ALA   N    N N N 43  
ALA   CA   C N S 44  
ALA   C    C N N 45  
ALA   O    O N N 46  
ALA   CB   C N N 47  
ALA   OXT  O N N 48  
ALA   H    H N N 49  
ALA   H2   H N N 50  
ALA   HA   H N N 51  
ALA   HB1  H N N 52  
ALA   HB2  H N N 53  
ALA   HB3  H N N 54  
ALA   HXT  H N N 55  
ARG   N    N N N 56  
ARG   CA   C N S 57  
ARG   C    C N N 58  
ARG   O    O N N 59  
ARG   CB   C N N 60  
ARG   CG   C N N 61  
ARG   CD   C N N 62  
ARG   NE   N N N 63  
ARG   CZ   C N N 64  
ARG   NH1  N N N 65  
ARG   NH2  N N N 66  
ARG   OXT  O N N 67  
ARG   H    H N N 68  
ARG   H2   H N N 69  
ARG   HA   H N N 70  
ARG   HB2  H N N 71  
ARG   HB3  H N N 72  
ARG   HG2  H N N 73  
ARG   HG3  H N N 74  
ARG   HD2  H N N 75  
ARG   HD3  H N N 76  
ARG   HE   H N N 77  
ARG   HH11 H N N 78  
ARG   HH12 H N N 79  
ARG   HH21 H N N 80  
ARG   HH22 H N N 81  
ARG   HXT  H N N 82  
ASN   N    N N N 83  
ASN   CA   C N S 84  
ASN   C    C N N 85  
ASN   O    O N N 86  
ASN   CB   C N N 87  
ASN   CG   C N N 88  
ASN   OD1  O N N 89  
ASN   ND2  N N N 90  
ASN   OXT  O N N 91  
ASN   H    H N N 92  
ASN   H2   H N N 93  
ASN   HA   H N N 94  
ASN   HB2  H N N 95  
ASN   HB3  H N N 96  
ASN   HD21 H N N 97  
ASN   HD22 H N N 98  
ASN   HXT  H N N 99  
ASP   N    N N N 100 
ASP   CA   C N S 101 
ASP   C    C N N 102 
ASP   O    O N N 103 
ASP   CB   C N N 104 
ASP   CG   C N N 105 
ASP   OD1  O N N 106 
ASP   OD2  O N N 107 
ASP   OXT  O N N 108 
ASP   H    H N N 109 
ASP   H2   H N N 110 
ASP   HA   H N N 111 
ASP   HB2  H N N 112 
ASP   HB3  H N N 113 
ASP   HD2  H N N 114 
ASP   HXT  H N N 115 
CYS   N    N N N 116 
CYS   CA   C N R 117 
CYS   C    C N N 118 
CYS   O    O N N 119 
CYS   CB   C N N 120 
CYS   SG   S N N 121 
CYS   OXT  O N N 122 
CYS   H    H N N 123 
CYS   H2   H N N 124 
CYS   HA   H N N 125 
CYS   HB2  H N N 126 
CYS   HB3  H N N 127 
CYS   HG   H N N 128 
CYS   HXT  H N N 129 
GLN   N    N N N 130 
GLN   CA   C N S 131 
GLN   C    C N N 132 
GLN   O    O N N 133 
GLN   CB   C N N 134 
GLN   CG   C N N 135 
GLN   CD   C N N 136 
GLN   OE1  O N N 137 
GLN   NE2  N N N 138 
GLN   OXT  O N N 139 
GLN   H    H N N 140 
GLN   H2   H N N 141 
GLN   HA   H N N 142 
GLN   HB2  H N N 143 
GLN   HB3  H N N 144 
GLN   HG2  H N N 145 
GLN   HG3  H N N 146 
GLN   HE21 H N N 147 
GLN   HE22 H N N 148 
GLN   HXT  H N N 149 
GLU   N    N N N 150 
GLU   CA   C N S 151 
GLU   C    C N N 152 
GLU   O    O N N 153 
GLU   CB   C N N 154 
GLU   CG   C N N 155 
GLU   CD   C N N 156 
GLU   OE1  O N N 157 
GLU   OE2  O N N 158 
GLU   OXT  O N N 159 
GLU   H    H N N 160 
GLU   H2   H N N 161 
GLU   HA   H N N 162 
GLU   HB2  H N N 163 
GLU   HB3  H N N 164 
GLU   HG2  H N N 165 
GLU   HG3  H N N 166 
GLU   HE2  H N N 167 
GLU   HXT  H N N 168 
GLY   N    N N N 169 
GLY   CA   C N N 170 
GLY   C    C N N 171 
GLY   O    O N N 172 
GLY   OXT  O N N 173 
GLY   H    H N N 174 
GLY   H2   H N N 175 
GLY   HA2  H N N 176 
GLY   HA3  H N N 177 
GLY   HXT  H N N 178 
HIS   N    N N N 179 
HIS   CA   C N S 180 
HIS   C    C N N 181 
HIS   O    O N N 182 
HIS   CB   C N N 183 
HIS   CG   C Y N 184 
HIS   ND1  N Y N 185 
HIS   CD2  C Y N 186 
HIS   CE1  C Y N 187 
HIS   NE2  N Y N 188 
HIS   OXT  O N N 189 
HIS   H    H N N 190 
HIS   H2   H N N 191 
HIS   HA   H N N 192 
HIS   HB2  H N N 193 
HIS   HB3  H N N 194 
HIS   HD1  H N N 195 
HIS   HD2  H N N 196 
HIS   HE1  H N N 197 
HIS   HE2  H N N 198 
HIS   HXT  H N N 199 
HOH   O    O N N 200 
HOH   H1   H N N 201 
HOH   H2   H N N 202 
ILE   N    N N N 203 
ILE   CA   C N S 204 
ILE   C    C N N 205 
ILE   O    O N N 206 
ILE   CB   C N S 207 
ILE   CG1  C N N 208 
ILE   CG2  C N N 209 
ILE   CD1  C N N 210 
ILE   OXT  O N N 211 
ILE   H    H N N 212 
ILE   H2   H N N 213 
ILE   HA   H N N 214 
ILE   HB   H N N 215 
ILE   HG12 H N N 216 
ILE   HG13 H N N 217 
ILE   HG21 H N N 218 
ILE   HG22 H N N 219 
ILE   HG23 H N N 220 
ILE   HD11 H N N 221 
ILE   HD12 H N N 222 
ILE   HD13 H N N 223 
ILE   HXT  H N N 224 
LEU   N    N N N 225 
LEU   CA   C N S 226 
LEU   C    C N N 227 
LEU   O    O N N 228 
LEU   CB   C N N 229 
LEU   CG   C N N 230 
LEU   CD1  C N N 231 
LEU   CD2  C N N 232 
LEU   OXT  O N N 233 
LEU   H    H N N 234 
LEU   H2   H N N 235 
LEU   HA   H N N 236 
LEU   HB2  H N N 237 
LEU   HB3  H N N 238 
LEU   HG   H N N 239 
LEU   HD11 H N N 240 
LEU   HD12 H N N 241 
LEU   HD13 H N N 242 
LEU   HD21 H N N 243 
LEU   HD22 H N N 244 
LEU   HD23 H N N 245 
LEU   HXT  H N N 246 
LYS   N    N N N 247 
LYS   CA   C N S 248 
LYS   C    C N N 249 
LYS   O    O N N 250 
LYS   CB   C N N 251 
LYS   CG   C N N 252 
LYS   CD   C N N 253 
LYS   CE   C N N 254 
LYS   NZ   N N N 255 
LYS   OXT  O N N 256 
LYS   H    H N N 257 
LYS   H2   H N N 258 
LYS   HA   H N N 259 
LYS   HB2  H N N 260 
LYS   HB3  H N N 261 
LYS   HG2  H N N 262 
LYS   HG3  H N N 263 
LYS   HD2  H N N 264 
LYS   HD3  H N N 265 
LYS   HE2  H N N 266 
LYS   HE3  H N N 267 
LYS   HZ1  H N N 268 
LYS   HZ2  H N N 269 
LYS   HZ3  H N N 270 
LYS   HXT  H N N 271 
MET   N    N N N 272 
MET   CA   C N S 273 
MET   C    C N N 274 
MET   O    O N N 275 
MET   CB   C N N 276 
MET   CG   C N N 277 
MET   SD   S N N 278 
MET   CE   C N N 279 
MET   OXT  O N N 280 
MET   H    H N N 281 
MET   H2   H N N 282 
MET   HA   H N N 283 
MET   HB2  H N N 284 
MET   HB3  H N N 285 
MET   HG2  H N N 286 
MET   HG3  H N N 287 
MET   HE1  H N N 288 
MET   HE2  H N N 289 
MET   HE3  H N N 290 
MET   HXT  H N N 291 
PHE   N    N N N 292 
PHE   CA   C N S 293 
PHE   C    C N N 294 
PHE   O    O N N 295 
PHE   CB   C N N 296 
PHE   CG   C Y N 297 
PHE   CD1  C Y N 298 
PHE   CD2  C Y N 299 
PHE   CE1  C Y N 300 
PHE   CE2  C Y N 301 
PHE   CZ   C Y N 302 
PHE   OXT  O N N 303 
PHE   H    H N N 304 
PHE   H2   H N N 305 
PHE   HA   H N N 306 
PHE   HB2  H N N 307 
PHE   HB3  H N N 308 
PHE   HD1  H N N 309 
PHE   HD2  H N N 310 
PHE   HE1  H N N 311 
PHE   HE2  H N N 312 
PHE   HZ   H N N 313 
PHE   HXT  H N N 314 
PRO   N    N N N 315 
PRO   CA   C N S 316 
PRO   C    C N N 317 
PRO   O    O N N 318 
PRO   CB   C N N 319 
PRO   CG   C N N 320 
PRO   CD   C N N 321 
PRO   OXT  O N N 322 
PRO   H    H N N 323 
PRO   HA   H N N 324 
PRO   HB2  H N N 325 
PRO   HB3  H N N 326 
PRO   HG2  H N N 327 
PRO   HG3  H N N 328 
PRO   HD2  H N N 329 
PRO   HD3  H N N 330 
PRO   HXT  H N N 331 
SER   N    N N N 332 
SER   CA   C N S 333 
SER   C    C N N 334 
SER   O    O N N 335 
SER   CB   C N N 336 
SER   OG   O N N 337 
SER   OXT  O N N 338 
SER   H    H N N 339 
SER   H2   H N N 340 
SER   HA   H N N 341 
SER   HB2  H N N 342 
SER   HB3  H N N 343 
SER   HG   H N N 344 
SER   HXT  H N N 345 
THR   N    N N N 346 
THR   CA   C N S 347 
THR   C    C N N 348 
THR   O    O N N 349 
THR   CB   C N R 350 
THR   OG1  O N N 351 
THR   CG2  C N N 352 
THR   OXT  O N N 353 
THR   H    H N N 354 
THR   H2   H N N 355 
THR   HA   H N N 356 
THR   HB   H N N 357 
THR   HG1  H N N 358 
THR   HG21 H N N 359 
THR   HG22 H N N 360 
THR   HG23 H N N 361 
THR   HXT  H N N 362 
TRP   N    N N N 363 
TRP   CA   C N S 364 
TRP   C    C N N 365 
TRP   O    O N N 366 
TRP   CB   C N N 367 
TRP   CG   C Y N 368 
TRP   CD1  C Y N 369 
TRP   CD2  C Y N 370 
TRP   NE1  N Y N 371 
TRP   CE2  C Y N 372 
TRP   CE3  C Y N 373 
TRP   CZ2  C Y N 374 
TRP   CZ3  C Y N 375 
TRP   CH2  C Y N 376 
TRP   OXT  O N N 377 
TRP   H    H N N 378 
TRP   H2   H N N 379 
TRP   HA   H N N 380 
TRP   HB2  H N N 381 
TRP   HB3  H N N 382 
TRP   HD1  H N N 383 
TRP   HE1  H N N 384 
TRP   HE3  H N N 385 
TRP   HZ2  H N N 386 
TRP   HZ3  H N N 387 
TRP   HH2  H N N 388 
TRP   HXT  H N N 389 
TYR   N    N N N 390 
TYR   CA   C N S 391 
TYR   C    C N N 392 
TYR   O    O N N 393 
TYR   CB   C N N 394 
TYR   CG   C Y N 395 
TYR   CD1  C Y N 396 
TYR   CD2  C Y N 397 
TYR   CE1  C Y N 398 
TYR   CE2  C Y N 399 
TYR   CZ   C Y N 400 
TYR   OH   O N N 401 
TYR   OXT  O N N 402 
TYR   H    H N N 403 
TYR   H2   H N N 404 
TYR   HA   H N N 405 
TYR   HB2  H N N 406 
TYR   HB3  H N N 407 
TYR   HD1  H N N 408 
TYR   HD2  H N N 409 
TYR   HE1  H N N 410 
TYR   HE2  H N N 411 
TYR   HH   H N N 412 
TYR   HXT  H N N 413 
VAL   N    N N N 414 
VAL   CA   C N S 415 
VAL   C    C N N 416 
VAL   O    O N N 417 
VAL   CB   C N N 418 
VAL   CG1  C N N 419 
VAL   CG2  C N N 420 
VAL   OXT  O N N 421 
VAL   H    H N N 422 
VAL   H2   H N N 423 
VAL   HA   H N N 424 
VAL   HB   H N N 425 
VAL   HG11 H N N 426 
VAL   HG12 H N N 427 
VAL   HG13 H N N 428 
VAL   HG21 H N N 429 
VAL   HG22 H N N 430 
VAL   HG23 H N N 431 
VAL   HXT  H N N 432 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
A1L1N C1  N1   sing N N 1   
A1L1N C1  C5   sing N N 2   
A1L1N N1  C2   sing N N 3   
A1L1N N1  C10  sing N N 4   
A1L1N C2  C3   sing N N 5   
A1L1N C3  C4   doub Y N 6   
A1L1N C3  C6   sing Y N 7   
A1L1N C4  C5   sing N N 8   
A1L1N C4  C9   sing Y N 9   
A1L1N C6  C7   doub Y N 10  
A1L1N C7  C8   sing Y N 11  
A1L1N C7  C13  sing N N 12  
A1L1N C8  C9   doub Y N 13  
A1L1N C10 C11  sing N N 14  
A1L1N C10 O1   doub N N 15  
A1L1N C11 C12  sing N N 16  
A1L1N C11 F4   sing N N 17  
A1L1N C13 C14  doub Y N 18  
A1L1N C13 C18  sing Y N 19  
A1L1N C14 C15  sing Y N 20  
A1L1N C15 C16  doub Y N 21  
A1L1N C16 C17  sing Y N 22  
A1L1N C16 C19  sing N N 23  
A1L1N C17 C18  doub Y N 24  
A1L1N C19 F1   sing N N 25  
A1L1N C19 F2   sing N N 26  
A1L1N C19 F3   sing N N 27  
A1L1N C5  H52  sing N N 28  
A1L1N C5  H51  sing N N 29  
A1L1N C6  H61  sing N N 30  
A1L1N C8  H81  sing N N 31  
A1L1N C15 H151 sing N N 32  
A1L1N C17 H171 sing N N 33  
A1L1N C1  H11  sing N N 34  
A1L1N C1  H12  sing N N 35  
A1L1N C11 H111 sing N N 36  
A1L1N C12 H122 sing N N 37  
A1L1N C12 H123 sing N N 38  
A1L1N C12 H121 sing N N 39  
A1L1N C14 H141 sing N N 40  
A1L1N C18 H181 sing N N 41  
A1L1N C2  H23  sing N N 42  
A1L1N C2  H22  sing N N 43  
A1L1N C9  H91  sing N N 44  
ALA   N   CA   sing N N 45  
ALA   N   H    sing N N 46  
ALA   N   H2   sing N N 47  
ALA   CA  C    sing N N 48  
ALA   CA  CB   sing N N 49  
ALA   CA  HA   sing N N 50  
ALA   C   O    doub N N 51  
ALA   C   OXT  sing N N 52  
ALA   CB  HB1  sing N N 53  
ALA   CB  HB2  sing N N 54  
ALA   CB  HB3  sing N N 55  
ALA   OXT HXT  sing N N 56  
ARG   N   CA   sing N N 57  
ARG   N   H    sing N N 58  
ARG   N   H2   sing N N 59  
ARG   CA  C    sing N N 60  
ARG   CA  CB   sing N N 61  
ARG   CA  HA   sing N N 62  
ARG   C   O    doub N N 63  
ARG   C   OXT  sing N N 64  
ARG   CB  CG   sing N N 65  
ARG   CB  HB2  sing N N 66  
ARG   CB  HB3  sing N N 67  
ARG   CG  CD   sing N N 68  
ARG   CG  HG2  sing N N 69  
ARG   CG  HG3  sing N N 70  
ARG   CD  NE   sing N N 71  
ARG   CD  HD2  sing N N 72  
ARG   CD  HD3  sing N N 73  
ARG   NE  CZ   sing N N 74  
ARG   NE  HE   sing N N 75  
ARG   CZ  NH1  sing N N 76  
ARG   CZ  NH2  doub N N 77  
ARG   NH1 HH11 sing N N 78  
ARG   NH1 HH12 sing N N 79  
ARG   NH2 HH21 sing N N 80  
ARG   NH2 HH22 sing N N 81  
ARG   OXT HXT  sing N N 82  
ASN   N   CA   sing N N 83  
ASN   N   H    sing N N 84  
ASN   N   H2   sing N N 85  
ASN   CA  C    sing N N 86  
ASN   CA  CB   sing N N 87  
ASN   CA  HA   sing N N 88  
ASN   C   O    doub N N 89  
ASN   C   OXT  sing N N 90  
ASN   CB  CG   sing N N 91  
ASN   CB  HB2  sing N N 92  
ASN   CB  HB3  sing N N 93  
ASN   CG  OD1  doub N N 94  
ASN   CG  ND2  sing N N 95  
ASN   ND2 HD21 sing N N 96  
ASN   ND2 HD22 sing N N 97  
ASN   OXT HXT  sing N N 98  
ASP   N   CA   sing N N 99  
ASP   N   H    sing N N 100 
ASP   N   H2   sing N N 101 
ASP   CA  C    sing N N 102 
ASP   CA  CB   sing N N 103 
ASP   CA  HA   sing N N 104 
ASP   C   O    doub N N 105 
ASP   C   OXT  sing N N 106 
ASP   CB  CG   sing N N 107 
ASP   CB  HB2  sing N N 108 
ASP   CB  HB3  sing N N 109 
ASP   CG  OD1  doub N N 110 
ASP   CG  OD2  sing N N 111 
ASP   OD2 HD2  sing N N 112 
ASP   OXT HXT  sing N N 113 
CYS   N   CA   sing N N 114 
CYS   N   H    sing N N 115 
CYS   N   H2   sing N N 116 
CYS   CA  C    sing N N 117 
CYS   CA  CB   sing N N 118 
CYS   CA  HA   sing N N 119 
CYS   C   O    doub N N 120 
CYS   C   OXT  sing N N 121 
CYS   CB  SG   sing N N 122 
CYS   CB  HB2  sing N N 123 
CYS   CB  HB3  sing N N 124 
CYS   SG  HG   sing N N 125 
CYS   OXT HXT  sing N N 126 
GLN   N   CA   sing N N 127 
GLN   N   H    sing N N 128 
GLN   N   H2   sing N N 129 
GLN   CA  C    sing N N 130 
GLN   CA  CB   sing N N 131 
GLN   CA  HA   sing N N 132 
GLN   C   O    doub N N 133 
GLN   C   OXT  sing N N 134 
GLN   CB  CG   sing N N 135 
GLN   CB  HB2  sing N N 136 
GLN   CB  HB3  sing N N 137 
GLN   CG  CD   sing N N 138 
GLN   CG  HG2  sing N N 139 
GLN   CG  HG3  sing N N 140 
GLN   CD  OE1  doub N N 141 
GLN   CD  NE2  sing N N 142 
GLN   NE2 HE21 sing N N 143 
GLN   NE2 HE22 sing N N 144 
GLN   OXT HXT  sing N N 145 
GLU   N   CA   sing N N 146 
GLU   N   H    sing N N 147 
GLU   N   H2   sing N N 148 
GLU   CA  C    sing N N 149 
GLU   CA  CB   sing N N 150 
GLU   CA  HA   sing N N 151 
GLU   C   O    doub N N 152 
GLU   C   OXT  sing N N 153 
GLU   CB  CG   sing N N 154 
GLU   CB  HB2  sing N N 155 
GLU   CB  HB3  sing N N 156 
GLU   CG  CD   sing N N 157 
GLU   CG  HG2  sing N N 158 
GLU   CG  HG3  sing N N 159 
GLU   CD  OE1  doub N N 160 
GLU   CD  OE2  sing N N 161 
GLU   OE2 HE2  sing N N 162 
GLU   OXT HXT  sing N N 163 
GLY   N   CA   sing N N 164 
GLY   N   H    sing N N 165 
GLY   N   H2   sing N N 166 
GLY   CA  C    sing N N 167 
GLY   CA  HA2  sing N N 168 
GLY   CA  HA3  sing N N 169 
GLY   C   O    doub N N 170 
GLY   C   OXT  sing N N 171 
GLY   OXT HXT  sing N N 172 
HIS   N   CA   sing N N 173 
HIS   N   H    sing N N 174 
HIS   N   H2   sing N N 175 
HIS   CA  C    sing N N 176 
HIS   CA  CB   sing N N 177 
HIS   CA  HA   sing N N 178 
HIS   C   O    doub N N 179 
HIS   C   OXT  sing N N 180 
HIS   CB  CG   sing N N 181 
HIS   CB  HB2  sing N N 182 
HIS   CB  HB3  sing N N 183 
HIS   CG  ND1  sing Y N 184 
HIS   CG  CD2  doub Y N 185 
HIS   ND1 CE1  doub Y N 186 
HIS   ND1 HD1  sing N N 187 
HIS   CD2 NE2  sing Y N 188 
HIS   CD2 HD2  sing N N 189 
HIS   CE1 NE2  sing Y N 190 
HIS   CE1 HE1  sing N N 191 
HIS   NE2 HE2  sing N N 192 
HIS   OXT HXT  sing N N 193 
HOH   O   H1   sing N N 194 
HOH   O   H2   sing N N 195 
ILE   N   CA   sing N N 196 
ILE   N   H    sing N N 197 
ILE   N   H2   sing N N 198 
ILE   CA  C    sing N N 199 
ILE   CA  CB   sing N N 200 
ILE   CA  HA   sing N N 201 
ILE   C   O    doub N N 202 
ILE   C   OXT  sing N N 203 
ILE   CB  CG1  sing N N 204 
ILE   CB  CG2  sing N N 205 
ILE   CB  HB   sing N N 206 
ILE   CG1 CD1  sing N N 207 
ILE   CG1 HG12 sing N N 208 
ILE   CG1 HG13 sing N N 209 
ILE   CG2 HG21 sing N N 210 
ILE   CG2 HG22 sing N N 211 
ILE   CG2 HG23 sing N N 212 
ILE   CD1 HD11 sing N N 213 
ILE   CD1 HD12 sing N N 214 
ILE   CD1 HD13 sing N N 215 
ILE   OXT HXT  sing N N 216 
LEU   N   CA   sing N N 217 
LEU   N   H    sing N N 218 
LEU   N   H2   sing N N 219 
LEU   CA  C    sing N N 220 
LEU   CA  CB   sing N N 221 
LEU   CA  HA   sing N N 222 
LEU   C   O    doub N N 223 
LEU   C   OXT  sing N N 224 
LEU   CB  CG   sing N N 225 
LEU   CB  HB2  sing N N 226 
LEU   CB  HB3  sing N N 227 
LEU   CG  CD1  sing N N 228 
LEU   CG  CD2  sing N N 229 
LEU   CG  HG   sing N N 230 
LEU   CD1 HD11 sing N N 231 
LEU   CD1 HD12 sing N N 232 
LEU   CD1 HD13 sing N N 233 
LEU   CD2 HD21 sing N N 234 
LEU   CD2 HD22 sing N N 235 
LEU   CD2 HD23 sing N N 236 
LEU   OXT HXT  sing N N 237 
LYS   N   CA   sing N N 238 
LYS   N   H    sing N N 239 
LYS   N   H2   sing N N 240 
LYS   CA  C    sing N N 241 
LYS   CA  CB   sing N N 242 
LYS   CA  HA   sing N N 243 
LYS   C   O    doub N N 244 
LYS   C   OXT  sing N N 245 
LYS   CB  CG   sing N N 246 
LYS   CB  HB2  sing N N 247 
LYS   CB  HB3  sing N N 248 
LYS   CG  CD   sing N N 249 
LYS   CG  HG2  sing N N 250 
LYS   CG  HG3  sing N N 251 
LYS   CD  CE   sing N N 252 
LYS   CD  HD2  sing N N 253 
LYS   CD  HD3  sing N N 254 
LYS   CE  NZ   sing N N 255 
LYS   CE  HE2  sing N N 256 
LYS   CE  HE3  sing N N 257 
LYS   NZ  HZ1  sing N N 258 
LYS   NZ  HZ2  sing N N 259 
LYS   NZ  HZ3  sing N N 260 
LYS   OXT HXT  sing N N 261 
MET   N   CA   sing N N 262 
MET   N   H    sing N N 263 
MET   N   H2   sing N N 264 
MET   CA  C    sing N N 265 
MET   CA  CB   sing N N 266 
MET   CA  HA   sing N N 267 
MET   C   O    doub N N 268 
MET   C   OXT  sing N N 269 
MET   CB  CG   sing N N 270 
MET   CB  HB2  sing N N 271 
MET   CB  HB3  sing N N 272 
MET   CG  SD   sing N N 273 
MET   CG  HG2  sing N N 274 
MET   CG  HG3  sing N N 275 
MET   SD  CE   sing N N 276 
MET   CE  HE1  sing N N 277 
MET   CE  HE2  sing N N 278 
MET   CE  HE3  sing N N 279 
MET   OXT HXT  sing N N 280 
PHE   N   CA   sing N N 281 
PHE   N   H    sing N N 282 
PHE   N   H2   sing N N 283 
PHE   CA  C    sing N N 284 
PHE   CA  CB   sing N N 285 
PHE   CA  HA   sing N N 286 
PHE   C   O    doub N N 287 
PHE   C   OXT  sing N N 288 
PHE   CB  CG   sing N N 289 
PHE   CB  HB2  sing N N 290 
PHE   CB  HB3  sing N N 291 
PHE   CG  CD1  doub Y N 292 
PHE   CG  CD2  sing Y N 293 
PHE   CD1 CE1  sing Y N 294 
PHE   CD1 HD1  sing N N 295 
PHE   CD2 CE2  doub Y N 296 
PHE   CD2 HD2  sing N N 297 
PHE   CE1 CZ   doub Y N 298 
PHE   CE1 HE1  sing N N 299 
PHE   CE2 CZ   sing Y N 300 
PHE   CE2 HE2  sing N N 301 
PHE   CZ  HZ   sing N N 302 
PHE   OXT HXT  sing N N 303 
PRO   N   CA   sing N N 304 
PRO   N   CD   sing N N 305 
PRO   N   H    sing N N 306 
PRO   CA  C    sing N N 307 
PRO   CA  CB   sing N N 308 
PRO   CA  HA   sing N N 309 
PRO   C   O    doub N N 310 
PRO   C   OXT  sing N N 311 
PRO   CB  CG   sing N N 312 
PRO   CB  HB2  sing N N 313 
PRO   CB  HB3  sing N N 314 
PRO   CG  CD   sing N N 315 
PRO   CG  HG2  sing N N 316 
PRO   CG  HG3  sing N N 317 
PRO   CD  HD2  sing N N 318 
PRO   CD  HD3  sing N N 319 
PRO   OXT HXT  sing N N 320 
SER   N   CA   sing N N 321 
SER   N   H    sing N N 322 
SER   N   H2   sing N N 323 
SER   CA  C    sing N N 324 
SER   CA  CB   sing N N 325 
SER   CA  HA   sing N N 326 
SER   C   O    doub N N 327 
SER   C   OXT  sing N N 328 
SER   CB  OG   sing N N 329 
SER   CB  HB2  sing N N 330 
SER   CB  HB3  sing N N 331 
SER   OG  HG   sing N N 332 
SER   OXT HXT  sing N N 333 
THR   N   CA   sing N N 334 
THR   N   H    sing N N 335 
THR   N   H2   sing N N 336 
THR   CA  C    sing N N 337 
THR   CA  CB   sing N N 338 
THR   CA  HA   sing N N 339 
THR   C   O    doub N N 340 
THR   C   OXT  sing N N 341 
THR   CB  OG1  sing N N 342 
THR   CB  CG2  sing N N 343 
THR   CB  HB   sing N N 344 
THR   OG1 HG1  sing N N 345 
THR   CG2 HG21 sing N N 346 
THR   CG2 HG22 sing N N 347 
THR   CG2 HG23 sing N N 348 
THR   OXT HXT  sing N N 349 
TRP   N   CA   sing N N 350 
TRP   N   H    sing N N 351 
TRP   N   H2   sing N N 352 
TRP   CA  C    sing N N 353 
TRP   CA  CB   sing N N 354 
TRP   CA  HA   sing N N 355 
TRP   C   O    doub N N 356 
TRP   C   OXT  sing N N 357 
TRP   CB  CG   sing N N 358 
TRP   CB  HB2  sing N N 359 
TRP   CB  HB3  sing N N 360 
TRP   CG  CD1  doub Y N 361 
TRP   CG  CD2  sing Y N 362 
TRP   CD1 NE1  sing Y N 363 
TRP   CD1 HD1  sing N N 364 
TRP   CD2 CE2  doub Y N 365 
TRP   CD2 CE3  sing Y N 366 
TRP   NE1 CE2  sing Y N 367 
TRP   NE1 HE1  sing N N 368 
TRP   CE2 CZ2  sing Y N 369 
TRP   CE3 CZ3  doub Y N 370 
TRP   CE3 HE3  sing N N 371 
TRP   CZ2 CH2  doub Y N 372 
TRP   CZ2 HZ2  sing N N 373 
TRP   CZ3 CH2  sing Y N 374 
TRP   CZ3 HZ3  sing N N 375 
TRP   CH2 HH2  sing N N 376 
TRP   OXT HXT  sing N N 377 
TYR   N   CA   sing N N 378 
TYR   N   H    sing N N 379 
TYR   N   H2   sing N N 380 
TYR   CA  C    sing N N 381 
TYR   CA  CB   sing N N 382 
TYR   CA  HA   sing N N 383 
TYR   C   O    doub N N 384 
TYR   C   OXT  sing N N 385 
TYR   CB  CG   sing N N 386 
TYR   CB  HB2  sing N N 387 
TYR   CB  HB3  sing N N 388 
TYR   CG  CD1  doub Y N 389 
TYR   CG  CD2  sing Y N 390 
TYR   CD1 CE1  sing Y N 391 
TYR   CD1 HD1  sing N N 392 
TYR   CD2 CE2  doub Y N 393 
TYR   CD2 HD2  sing N N 394 
TYR   CE1 CZ   doub Y N 395 
TYR   CE1 HE1  sing N N 396 
TYR   CE2 CZ   sing Y N 397 
TYR   CE2 HE2  sing N N 398 
TYR   CZ  OH   sing N N 399 
TYR   OH  HH   sing N N 400 
TYR   OXT HXT  sing N N 401 
VAL   N   CA   sing N N 402 
VAL   N   H    sing N N 403 
VAL   N   H2   sing N N 404 
VAL   CA  C    sing N N 405 
VAL   CA  CB   sing N N 406 
VAL   CA  HA   sing N N 407 
VAL   C   O    doub N N 408 
VAL   C   OXT  sing N N 409 
VAL   CB  CG1  sing N N 410 
VAL   CB  CG2  sing N N 411 
VAL   CB  HB   sing N N 412 
VAL   CG1 HG11 sing N N 413 
VAL   CG1 HG12 sing N N 414 
VAL   CG1 HG13 sing N N 415 
VAL   CG2 HG21 sing N N 416 
VAL   CG2 HG22 sing N N 417 
VAL   CG2 HG23 sing N N 418 
VAL   OXT HXT  sing N N 419 
# 
_pdbx_audit_support.funding_organization   'Not funded' 
_pdbx_audit_support.country                ? 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   7ZJQ 
_pdbx_initial_refinement_model.details          ? 
# 
_space_group.name_H-M_alt     'P 21 21 21' 
_space_group.name_Hall        'P 2ac 2ab' 
_space_group.IT_number        19 
_space_group.crystal_system   orthorhombic 
_space_group.id               1 
# 
_atom_sites.entry_id                    8ZBG 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.021631 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.009885 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.006718 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C ? ? 3.54356 2.42580 ? ? 25.62398 1.50364  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
F ? ? 8.95735 ?       ? ? 7.27484  ?        ? ? 0.0 
;1-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N ? ? 4.01032 2.96436 ? ? 19.97189 1.75589  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O ? ? 7.96527 ?       ? ? 9.05267  ?        ? ? 0.0 
;1-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S ? ? 9.55732 6.39887 ? ? 1.23737  29.19336 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . ASP   A 1 3   ? -11.79876 -4.62384  4.63424   1.000 94.16000  ? 217 ASP   A N   1 
ATOM   2    C CA  . ASP   A 1 3   ? -12.99870 -5.39600  4.82696   1.000 97.83000  ? 217 ASP   A CA  1 
ATOM   3    C C   . ASP   A 1 3   ? -12.54059 -6.80191  4.68453   1.000 94.78000  ? 217 ASP   A C   1 
ATOM   4    O O   . ASP   A 1 3   ? -13.09650 -7.54871  3.89028   1.000 90.36000  ? 217 ASP   A O   1 
ATOM   5    C CB  . ASP   A 1 3   ? -14.01070 -5.07574  3.75103   1.000 95.34000  ? 217 ASP   A CB  1 
ATOM   6    C CG  . ASP   A 1 3   ? -13.40765 -5.06226  2.37305   1.000 96.41000  ? 217 ASP   A CG  1 
ATOM   7    O OD1 . ASP   A 1 3   ? -12.54072 -4.20611  2.11234   1.000 103.99000 ? 217 ASP   A OD1 1 
ATOM   8    O OD2 . ASP   A 1 3   ? -13.81156 -5.90204  1.54677   1.000 93.81000  ? 217 ASP   A OD2 1 
ATOM   9    N N   . ARG   A 1 4   ? -11.50258 -7.15306  5.42546   1.000 85.77000  ? 218 ARG   A N   1 
ATOM   10   C CA  . ARG   A 1 4   ? -10.92747 -8.47898  5.32806   1.000 83.43000  ? 218 ARG   A CA  1 
ATOM   11   C C   . ARG   A 1 4   ? -10.15043 -8.54552  4.03007   1.000 84.63000  ? 218 ARG   A C   1 
ATOM   12   O O   . ARG   A 1 4   ? -9.77433  -9.60835  3.57575   1.000 86.48000  ? 218 ARG   A O   1 
ATOM   13   C CB  . ARG   A 1 4   ? -11.99239 -9.56711  5.45269   1.000 92.14000  ? 218 ARG   A CB  1 
ATOM   14   C CG  . ARG   A 1 4   ? -11.46729 -10.92521 5.89728   1.000 91.86000  ? 218 ARG   A CG  1 
ATOM   15   C CD  . ARG   A 1 4   ? -11.32018 -11.88383 4.72499   1.000 93.81000  ? 218 ARG   A CD  1 
ATOM   16   N NE  . ARG   A 1 4   ? -10.40310 -12.97885 5.02168   1.000 96.69000  ? 218 ARG   A NE  1 
ATOM   17   C CZ  . ARG   A 1 4   ? -9.08910  -12.92868 4.82973   1.000 95.07000  ? 218 ARG   A CZ  1 
ATOM   18   N NH1 . ARG   A 1 4   ? -8.52817  -11.83048 4.34309   1.000 85.56000  ? 218 ARG   A NH1 1 
ATOM   19   N NH2 . ARG   A 1 4   ? -8.33102  -13.97471 5.12443   1.000 97.08000  ? 218 ARG   A NH2 1 
ATOM   20   N N   . THR   A 1 5   ? -9.87250  -7.39631  3.44743   1.000 80.10000  ? 219 THR   A N   1 
ATOM   21   C CA  . THR   A 1 5   ? -9.14046  -7.34987  2.20247   1.000 74.45000  ? 219 THR   A CA  1 
ATOM   22   C C   . THR   A 1 5   ? -7.90154  -6.52284  2.42777   1.000 66.09000  ? 219 THR   A C   1 
ATOM   23   O O   . THR   A 1 5   ? -7.93364  -5.54007  3.15307   1.000 65.57000  ? 219 THR   A O   1 
ATOM   24   C CB  . THR   A 1 5   ? -9.96848  -6.74158  1.05963   1.000 63.37000  ? 219 THR   A CB  1 
ATOM   25   O OG1 . THR   A 1 5   ? -10.39360 -5.42973  1.43003   1.000 63.34000  ? 219 THR   A OG1 1 
ATOM   26   C CG2 . THR   A 1 5   ? -11.17340 -7.59959  0.77333   1.000 66.29000  ? 219 THR   A CG2 1 
ATOM   27   N N   . ILE   A 1 6   ? -6.80349  -6.91856  1.80768   1.000 59.65000  ? 220 ILE   A N   1 
ATOM   28   C CA  . ILE   A 1 6   ? -5.58855  -6.17550  1.95795   1.000 54.40000  ? 220 ILE   A CA  1 
ATOM   29   C C   . ILE   A 1 6   ? -5.72861  -5.08221  0.96228   1.000 55.49000  ? 220 ILE   A C   1 
ATOM   30   O O   . ILE   A 1 6   ? -5.09858  -5.08083  -0.07970  1.000 62.01000  ? 220 ILE   A O   1 
ATOM   31   C CB  . ILE   A 1 6   ? -4.38047  -7.03530  1.60372   1.000 51.69000  ? 220 ILE   A CB  1 
ATOM   32   C CG1 . ILE   A 1 6   ? -4.43839  -8.35254  2.37130   1.000 54.12000  ? 220 ILE   A CG1 1 
ATOM   33   C CG2 . ILE   A 1 6   ? -3.09154  -6.29429  1.91199   1.000 52.89000  ? 220 ILE   A CG2 1 
ATOM   34   C CD1 . ILE   A 1 6   ? -3.34130  -9.32234  2.00604   1.000 50.25000  ? 220 ILE   A CD1 1 
ATOM   35   N N   . ALA   A 1 7   ? -6.61969  -4.16037  1.26954   1.000 52.75000  ? 221 ALA   A N   1 
ATOM   36   C CA  . ALA   A 1 7   ? -6.87375  -3.07411  0.35087   1.000 60.86000  ? 221 ALA   A CA  1 
ATOM   37   C C   . ALA   A 1 7   ? -6.83988  -1.65027  0.86832   1.000 60.11000  ? 221 ALA   A C   1 
ATOM   38   O O   . ALA   A 1 7   ? -7.44494  -1.35263  1.88239   1.000 66.05000  ? 221 ALA   A O   1 
ATOM   39   C CB  . ALA   A 1 7   ? -8.22371  -3.32101  -0.29825  1.000 58.16000  ? 221 ALA   A CB  1 
ATOM   40   N N   . SER   A 1 8   ? -6.12293  -0.77700  0.20261   1.000 51.19000  ? 222 SER   A N   1 
ATOM   41   C CA  . SER   A 1 8   ? -6.17706  0.63490   0.50005   1.000 56.46000  ? 222 SER   A CA  1 
ATOM   42   C C   . SER   A 1 8   ? -7.37908  1.18202   -0.19282  1.000 57.01000  ? 222 SER   A C   1 
ATOM   43   O O   . SER   A 1 8   ? -7.96900  0.51923   -1.02204  1.000 55.97000  ? 222 SER   A O   1 
ATOM   44   C CB  . SER   A 1 8   ? -4.97510  1.37316   -0.02669  1.000 57.67000  ? 222 SER   A CB  1 
ATOM   45   O OG  . SER   A 1 8   ? -5.04507  1.53559   -1.42264  1.000 53.72000  ? 222 SER   A OG  1 
ATOM   46   N N   . SER   A 1 9   ? -7.80019  2.36588   0.16654   1.000 54.37000  ? 223 SER   A N   1 
ATOM   47   C CA  . SER   A 1 9   ? -8.85621  2.99702   -0.58330  1.000 60.09000  ? 223 SER   A CA  1 
ATOM   48   C C   . SER   A 1 9   ? -8.49718  3.10751   -2.06826  1.000 63.04000  ? 223 SER   A C   1 
ATOM   49   O O   . SER   A 1 9   ? -9.36417  3.36170   -2.89120  1.000 59.26000  ? 223 SER   A O   1 
ATOM   50   C CB  . SER   A 1 9   ? -9.11234  4.38783   -0.01388  1.000 63.29000  ? 223 SER   A CB  1 
ATOM   51   O OG  . SER   A 1 9   ? -7.92540  5.15592   -0.01060  1.000 70.53000  ? 223 SER   A OG  1 
ATOM   52   N N   . ARG   A 1 10  ? -7.23215  2.91673   -2.41828  1.000 55.04000  ? 224 ARG   A N   1 
ATOM   53   C CA  . ARG   A 1 10  ? -6.77512  3.05319   -3.79322  1.000 57.23000  ? 224 ARG   A CA  1 
ATOM   54   C C   . ARG   A 1 10  ? -6.37799  1.74043   -4.45162  1.000 57.32000  ? 224 ARG   A C   1 
ATOM   55   O O   . ARG   A 1 10  ? -6.40594  1.64681   -5.67965  1.000 59.34000  ? 224 ARG   A O   1 
ATOM   56   C CB  . ARG   A 1 10  ? -5.56619  3.98731   -3.86489  1.000 55.10000  ? 224 ARG   A CB  1 
ATOM   57   C CG  . ARG   A 1 10  ? -5.67932  5.25105   -3.06350  1.000 62.33000  ? 224 ARG   A CG  1 
ATOM   58   C CD  . ARG   A 1 10  ? -6.18638  6.40427   -3.91016  1.000 60.95000  ? 224 ARG   A CD  1 
ATOM   59   N NE  . ARG   A 1 10  ? -5.08142  7.06458   -4.59692  1.000 62.56000  ? 224 ARG   A NE  1 
ATOM   60   C CZ  . ARG   A 1 10  ? -4.85337  6.97400   -5.90494  1.000 64.27000  ? 224 ARG   A CZ  1 
ATOM   61   N NH1 . ARG   A 1 10  ? -5.67629  6.31719   -6.70917  1.000 61.35000  ? 224 ARG   A NH1 1 
ATOM   62   N NH2 . ARG   A 1 10  ? -3.76540  7.54625   -6.41573  1.000 60.97000  ? 224 ARG   A NH2 1 
ATOM   63   N N   . LEU   A 1 11  ? -5.95493  0.74023   -3.69491  1.000 51.78000  ? 225 LEU   A N   1 
ATOM   64   C CA  . LEU   A 1 11  ? -5.32382  -0.40353  -4.32825  1.000 48.66000  ? 225 LEU   A CA  1 
ATOM   65   C C   . LEU   A 1 11  ? -5.59075  -1.62781  -3.48164  1.000 51.28000  ? 225 LEU   A C   1 
ATOM   66   O O   . LEU   A 1 11  ? -5.60079  -1.55219  -2.25462  1.000 56.89000  ? 225 LEU   A O   1 
ATOM   67   C CB  . LEU   A 1 11  ? -3.80183  -0.17434  -4.52713  1.000 50.83000  ? 225 LEU   A CB  1 
ATOM   68   C CG  . LEU   A 1 11  ? -3.02272  -1.30406  -5.22846  1.000 52.87000  ? 225 LEU   A CG  1 
ATOM   69   C CD1 . LEU   A 1 11  ? -3.49966  -1.47866  -6.64153  1.000 49.72000  ? 225 LEU   A CD1 1 
ATOM   70   C CD2 . LEU   A 1 11  ? -1.53074  -1.06894  -5.23734  1.000 47.59000  ? 225 LEU   A CD2 1 
ATOM   71   N N   . ARG   A 1 12  ? -5.84164  -2.74563  -4.13999  1.000 54.54000  ? 226 ARG   A N   1 
ATOM   72   C CA  . ARG   A 1 12  ? -6.12956  -4.00386  -3.47340  1.000 54.06000  ? 226 ARG   A CA  1 
ATOM   73   C C   . ARG   A 1 12  ? -5.15546  -5.05362  -3.98169  1.000 56.76000  ? 226 ARG   A C   1 
ATOM   74   O O   . ARG   A 1 12  ? -4.96741  -5.18823  -5.19673  1.000 56.68000  ? 226 ARG   A O   1 
ATOM   75   C CB  . ARG   A 1 12  ? -7.56851  -4.44389  -3.74258  1.000 58.37000  ? 226 ARG   A CB  1 
ATOM   76   C CG  . ARG   A 1 12  ? -7.75340  -5.93092  -3.68705  1.000 55.17000  ? 226 ARG   A CG  1 
ATOM   77   C CD  . ARG   A 1 12  ? -8.52740  -6.30236  -2.47719  1.000 60.32000  ? 226 ARG   A CD  1 
ATOM   78   N NE  . ARG   A 1 12  ? -8.99229  -7.67738  -2.52363  1.000 62.26000  ? 226 ARG   A NE  1 
ATOM   79   C CZ  . ARG   A 1 12  ? -10.09424 -8.06028  -3.14278  1.000 47.23000  ? 226 ARG   A CZ  1 
ATOM   80   N NH1 . ARG   A 1 12  ? -10.79829 -7.21111  -3.86254  1.000 52.75000  ? 226 ARG   A NH1 1 
ATOM   81   N NH2 . ARG   A 1 12  ? -10.50514 -9.32035  -3.02219  1.000 52.86000  ? 226 ARG   A NH2 1 
ATOM   82   N N   . LEU   A 1 13  ? -4.52443  -5.78185  -3.06590  1.000 52.12000  ? 227 LEU   A N   1 
ATOM   83   C CA  . LEU   A 1 13  ? -3.68032  -6.89967  -3.45022  1.000 48.17000  ? 227 LEU   A CA  1 
ATOM   84   C C   . LEU   A 1 13  ? -4.58722  -8.10267  -3.68562  1.000 50.09000  ? 227 LEU   A C   1 
ATOM   85   O O   . LEU   A 1 13  ? -5.16321  -8.63601  -2.73981  1.000 54.15000  ? 227 LEU   A O   1 
ATOM   86   C CB  . LEU   A 1 13  ? -2.64433  -7.19492  -2.37528  1.000 48.80000  ? 227 LEU   A CB  1 
ATOM   87   C CG  . LEU   A 1 13  ? -2.00622  -8.56879  -2.61069  1.000 52.74000  ? 227 LEU   A CG  1 
ATOM   88   C CD1 . LEU   A 1 13  ? -1.21518  -8.53032  -3.91165  1.000 51.51000  ? 227 LEU   A CD1 1 
ATOM   89   C CD2 . LEU   A 1 13  ? -1.12822  -9.00908  -1.46280  1.000 53.41000  ? 227 LEU   A CD2 1 
ATOM   90   N N   . LEU   A 1 14  ? -4.71815  -8.54329  -4.93976  1.000 49.36000  ? 228 LEU   A N   1 
ATOM   91   C CA  . LEU   A 1 14  ? -5.61405  -9.66728  -5.19014  1.000 51.40000  ? 228 LEU   A CA  1 
ATOM   92   C C   . LEU   A 1 14  ? -4.95294  -11.01830 -4.96354  1.000 49.98000  ? 228 LEU   A C   1 
ATOM   93   O O   . LEU   A 1 14  ? -5.58189  -11.91952 -4.41484  1.000 53.80000  ? 228 LEU   A O   1 
ATOM   94   C CB  . LEU   A 1 14  ? -6.18301  -9.61589  -6.60714  1.000 57.07000  ? 228 LEU   A CB  1 
ATOM   95   C CG  . LEU   A 1 14  ? -7.09709  -8.47983  -7.03882  1.000 55.33000  ? 228 LEU   A CG  1 
ATOM   96   C CD1 . LEU   A 1 14  ? -7.36603  -8.61838  -8.53587  1.000 56.13000  ? 228 LEU   A CD1 1 
ATOM   97   C CD2 . LEU   A 1 14  ? -8.40110  -8.55218  -6.24088  1.000 49.36000  ? 228 LEU   A CD2 1 
ATOM   98   N N   . GLU   A 1 15  ? -3.72291  -11.21305 -5.42956  1.000 51.95000  ? 229 GLU   A N   1 
ATOM   99   C CA  . GLU   A 1 15  ? -3.07781  -12.51704 -5.31695  1.000 51.14000  ? 229 GLU   A CA  1 
ATOM   100  C C   . GLU   A 1 15  ? -1.58483  -12.32899 -5.09884  1.000 50.07000  ? 229 GLU   A C   1 
ATOM   101  O O   . GLU   A 1 15  ? -0.99890  -11.35978 -5.58953  1.000 45.00000  ? 229 GLU   A O   1 
ATOM   102  C CB  . GLU   A 1 15  ? -3.25771  -13.35166 -6.57722  1.000 58.04000  ? 229 GLU   A CB  1 
ATOM   103  C CG  . GLU   A 1 15  ? -4.57269  -13.24355 -7.26022  1.000 60.90000  ? 229 GLU   A CG  1 
ATOM   104  C CD  . GLU   A 1 15  ? -4.63858  -14.17220 -8.41951  1.000 67.72000  ? 229 GLU   A CD  1 
ATOM   105  O OE1 . GLU   A 1 15  ? -3.57253  -14.74001 -8.74766  1.000 53.67000  ? 229 GLU   A OE1 1 
ATOM   106  O OE2 . GLU   A 1 15  ? -5.73255  -14.29210 -9.02659  1.000 84.27000  ? 229 GLU   A OE2 1 
ATOM   107  N N   . TYR   A 1 16  ? -0.96978  -13.27716 -4.38112  1.000 45.45000  ? 230 TYR   A N   1 
ATOM   108  C CA  . TYR   A 1 16  ? 0.46421   -13.26813 -4.11307  1.000 41.67000  ? 230 TYR   A CA  1 
ATOM   109  C C   . TYR   A 1 16  ? 0.97832   -14.69812 -4.01650  1.000 46.32000  ? 230 TYR   A C   1 
ATOM   110  O O   . TYR   A 1 16  ? 0.46736   -15.49140 -3.22277  1.000 50.14000  ? 230 TYR   A O   1 
ATOM   111  C CB  . TYR   A 1 16  ? 0.80811   -12.50450 -2.82882  1.000 40.52000  ? 230 TYR   A CB  1 
ATOM   112  C CG  . TYR   A 1 16  ? 2.25307   -12.09339 -2.78965  1.000 45.44000  ? 230 TYR   A CG  1 
ATOM   113  C CD1 . TYR   A 1 16  ? 2.68500   -10.96014 -3.48529  1.000 51.98000  ? 230 TYR   A CD1 1 
ATOM   114  C CD2 . TYR   A 1 16  ? 3.19911   -12.84554 -2.09086  1.000 42.90000  ? 230 TYR   A CD2 1 
ATOM   115  C CE1 . TYR   A 1 16  ? 4.01497   -10.57903 -3.49213  1.000 49.43000  ? 230 TYR   A CE1 1 
ATOM   116  C CE2 . TYR   A 1 16  ? 4.53508   -12.47143 -2.07370  1.000 46.18000  ? 230 TYR   A CE2 1 
ATOM   117  C CZ  . TYR   A 1 16  ? 4.93901   -11.33618 -2.78433  1.000 54.43000  ? 230 TYR   A CZ  1 
ATOM   118  O OH  . TYR   A 1 16  ? 6.26198   -10.94407 -2.79217  1.000 54.40000  ? 230 TYR   A OH  1 
ATOM   119  N N   . SER   A 1 17  ? 1.98537   -15.02578 -4.82557  1.000 45.37000  ? 231 SER   A N   1 
ATOM   120  C CA  . SER   A 1 17  ? 2.58748   -16.35073 -4.84097  1.000 46.72000  ? 231 SER   A CA  1 
ATOM   121  C C   . SER   A 1 17  ? 4.09148   -16.25955 -5.01389  1.000 47.51000  ? 231 SER   A C   1 
ATOM   122  O O   . SER   A 1 17  ? 4.58745   -15.55624 -5.89866  1.000 47.07000  ? 231 SER   A O   1 
ATOM   123  C CB  . SER   A 1 17  ? 2.04659   -17.24942 -5.96226  1.000 44.12000  ? 231 SER   A CB  1 
ATOM   124  O OG  . SER   A 1 17  ? 0.97664   -18.03965 -5.50354  1.000 51.67000  ? 231 SER   A OG  1 
ATOM   125  N N   . ALA   A 1 18  ? 4.80451   -17.00176 -4.18010  1.000 49.22000  ? 232 ALA   A N   1 
ATOM   126  C CA  . ALA   A 1 18  ? 6.22354   -17.25559 -4.35913  1.000 43.85000  ? 232 ALA   A CA  1 
ATOM   127  C C   . ALA   A 1 18  ? 6.36767   -18.75251 -4.55260  1.000 47.46000  ? 232 ALA   A C   1 
ATOM   128  O O   . ALA   A 1 18  ? 5.83570   -19.53181 -3.74886  1.000 46.22000  ? 232 ALA   A O   1 
ATOM   129  C CB  . ALA   A 1 18  ? 7.03746   -16.76289 -3.16396  1.000 35.29000  ? 232 ALA   A CB  1 
ATOM   130  N N   . PHE   A 1 19  ? 7.04973   -19.15212 -5.63370  1.000 44.89000  ? 233 PHE   A N   1 
ATOM   131  C CA  . PHE   A 1 19  ? 6.97686   -20.52698 -6.10513  1.000 47.06000  ? 233 PHE   A CA  1 
ATOM   132  C C   . PHE   A 1 19  ? 8.29391   -20.96468 -6.74523  1.000 49.03000  ? 233 PHE   A C   1 
ATOM   133  O O   . PHE   A 1 19  ? 9.19686   -20.16152 -7.02695  1.000 46.49000  ? 233 PHE   A O   1 
ATOM   134  C CB  . PHE   A 1 19  ? 5.80290   -20.70977 -7.09622  1.000 44.47000  ? 233 PHE   A CB  1 
ATOM   135  C CG  . PHE   A 1 19  ? 5.92687   -19.87437 -8.33296  1.000 45.83000  ? 233 PHE   A CG  1 
ATOM   136  C CD1 . PHE   A 1 19  ? 5.45277   -18.57340 -8.36557  1.000 44.16000  ? 233 PHE   A CD1 1 
ATOM   137  C CD2 . PHE   A 1 19  ? 6.55395   -20.38197 -9.45910  1.000 49.39000  ? 233 PHE   A CD2 1 
ATOM   138  C CE1 . PHE   A 1 19  ? 5.58674   -17.79703 -9.51132  1.000 48.15000  ? 233 PHE   A CE1 1 
ATOM   139  C CE2 . PHE   A 1 19  ? 6.69493   -19.62160 -10.60186 1.000 49.40000  ? 233 PHE   A CE2 1 
ATOM   140  C CZ  . PHE   A 1 19  ? 6.20882   -18.32463 -10.63347 1.000 51.22000  ? 233 PHE   A CZ  1 
ATOM   141  N N   . MET   A 1 20  ? 8.38603   -22.28161 -6.94463  1.000 46.91000  ? 234 MET   A N   1 
ATOM   142  C CA  . MET   A 1 20  ? 9.46110   -22.92729 -7.68080  1.000 55.73000  ? 234 MET   A CA  1 
ATOM   143  C C   . MET   A 1 20  ? 8.82621   -23.84302 -8.71910  1.000 60.15000  ? 234 MET   A C   1 
ATOM   144  O O   . MET   A 1 20  ? 7.91526   -24.61619 -8.39337  1.000 62.67000  ? 234 MET   A O   1 
ATOM   145  C CB  . MET   A 1 20  ? 10.38014  -23.72251 -6.74802  1.000 60.52000  ? 234 MET   A CB  1 
ATOM   146  C CG  . MET   A 1 20  ? 10.93126  -25.00827 -7.35140  1.000 65.83000  ? 234 MET   A CG  1 
ATOM   147  S SD  . MET   A 1 20  ? 11.80630  -26.00758 -6.14169  1.000 90.82000  ? 234 MET   A SD  1 
ATOM   148  C CE  . MET   A 1 20  ? 10.65626  -26.02010 -4.75872  1.000 76.99000  ? 234 MET   A CE  1 
ATOM   149  N N   . GLU   A 1 21  ? 9.28624   -23.74059 -9.96306  1.000 48.74000  ? 235 GLU   A N   1 
ATOM   150  C CA  . GLU   A 1 21  ? 8.73033   -24.50429 -11.06931 1.000 55.59000  ? 235 GLU   A CA  1 
ATOM   151  C C   . GLU   A 1 21  ? 9.82942   -25.33801 -11.70154 1.000 54.61000  ? 235 GLU   A C   1 
ATOM   152  O O   . GLU   A 1 21  ? 10.92239  -24.82884 -11.96135 1.000 48.97000  ? 235 GLU   A O   1 
ATOM   153  C CB  . GLU   A 1 21  ? 8.09029   -23.59902 -12.12305 1.000 50.05000  ? 235 GLU   A CB  1 
ATOM   154  C CG  . GLU   A 1 21  ? 7.04638   -24.31784 -12.97631 1.000 59.45000  ? 235 GLU   A CG  1 
ATOM   155  C CD  . GLU   A 1 21  ? 6.41134   -23.42855 -14.06305 1.000 62.01000  ? 235 GLU   A CD  1 
ATOM   156  O OE1 . GLU   A 1 21  ? 7.15832   -22.87023 -14.89785 1.000 59.46000  ? 235 GLU   A OE1 1 
ATOM   157  O OE2 . GLU   A 1 21  ? 5.16333   -23.31764 -14.09706 1.000 57.63000  ? 235 GLU   A OE2 1 
ATOM   158  N N   . VAL   A 1 22  ? 9.53453   -26.61296 -11.94294 1.000 54.77000  ? 236 VAL   A N   1 
ATOM   159  C CA  . VAL   A 1 22  ? 10.46263  -27.54369 -12.56621 1.000 57.60000  ? 236 VAL   A CA  1 
ATOM   160  C C   . VAL   A 1 22  ? 9.77671   -28.17337 -13.77542 1.000 57.13000  ? 236 VAL   A C   1 
ATOM   161  O O   . VAL   A 1 22  ? 8.57274   -28.44747 -13.74755 1.000 51.88000  ? 236 VAL   A O   1 
ATOM   162  C CB  . VAL   A 1 22  ? 10.93468  -28.62796 -11.56453 1.000 63.34000  ? 236 VAL   A CB  1 
ATOM   163  C CG1 . VAL   A 1 22  ? 11.51880  -29.83369 -12.28989 1.000 63.39000  ? 236 VAL   A CG1 1 
ATOM   164  C CG2 . VAL   A 1 22  ? 11.94661  -28.06319 -10.57832 1.000 60.50000  ? 236 VAL   A CG2 1 
ATOM   165  N N   . GLN   A 1 23  ? 10.53677  -28.43598 -14.82248 1.000 63.69000  ? 237 GLN   A N   1 
ATOM   166  C CA  . GLN   A 1 23  ? 9.98386   -29.12067 -15.97471 1.000 63.49000  ? 237 GLN   A CA  1 
ATOM   167  C C   . GLN   A 1 23  ? 10.36497  -30.55866 -15.90215 1.000 60.79000  ? 237 GLN   A C   1 
ATOM   168  O O   . GLN   A 1 23  ? 11.53100  -30.89655 -15.95822 1.000 62.27000  ? 237 GLN   A O   1 
ATOM   169  C CB  . GLN   A 1 23  ? 10.53085  -28.55322 -17.26552 1.000 62.03000  ? 237 GLN   A CB  1 
ATOM   170  C CG  . GLN   A 1 23  ? 9.92494   -29.18589 -18.49973 1.000 63.85000  ? 237 GLN   A CG  1 
ATOM   171  C CD  . GLN   A 1 23  ? 10.41493  -28.55645 -19.78252 1.000 62.66000  ? 237 GLN   A CD  1 
ATOM   172  O OE1 . GLN   A 1 23  ? 11.38287  -27.80237 -19.78626 1.000 64.98000  ? 237 GLN   A OE1 1 
ATOM   173  N NE2 . GLN   A 1 23  ? 9.74799   -28.86416 -20.88064 1.000 63.62000  ? 237 GLN   A NE2 1 
ATOM   174  N N   . ARG   A 1 24  ? 9.37404   -31.41578 -15.77644 1.000 65.78000  ? 238 ARG   A N   1 
ATOM   175  C CA  . ARG   A 1 24  ? 9.65615   -32.84280 -15.64288 1.000 66.94000  ? 238 ARG   A CA  1 
ATOM   176  C C   . ARG   A 1 24  ? 9.91324   -33.49236 -16.99407 1.000 64.73000  ? 238 ARG   A C   1 
ATOM   177  O O   . ARG   A 1 24  ? 10.68632  -34.45227 -17.07635 1.000 69.90000  ? 238 ARG   A O   1 
ATOM   178  C CB  . ARG   A 1 24  ? 8.51018   -33.55912 -14.91314 1.000 71.55000  ? 238 ARG   A CB  1 
ATOM   179  C CG  . ARG   A 1 24  ? 8.29011   -33.13859 -13.45201 1.000 65.68000  ? 238 ARG   A CG  1 
ATOM   180  C CD  . ARG   A 1 24  ? 7.29716   -34.08888 -12.76234 1.000 80.97000  ? 238 ARG   A CD  1 
ATOM   181  N NE  . ARG   A 1 24  ? 6.45525   -34.82966 -13.70760 1.000 84.07000  ? 238 ARG   A NE  1 
ATOM   182  C CZ  . ARG   A 1 24  ? 5.34129   -35.47985 -13.38584 1.000 78.70000  ? 238 ARG   A CZ  1 
ATOM   183  N NH1 . ARG   A 1 24  ? 4.94326   -35.59127 -12.12588 1.000 73.74000  ? 238 ARG   A NH1 1 
ATOM   184  N NH2 . ARG   A 1 24  ? 4.61437   -36.04461 -14.34803 1.000 75.05000  ? 238 ARG   A NH2 1 
ATOM   185  N N   . ASP   A 1 25  ? 9.27724   -32.99108 -18.04194 1.000 62.00000  ? 239 ASP   A N   1 
ATOM   186  C CA  . ASP   A 1 25  ? 9.44832   -33.51264 -19.40110 1.000 70.39000  ? 239 ASP   A CA  1 
ATOM   187  C C   . ASP   A 1 25  ? 8.98326   -32.42838 -20.35777 1.000 66.13000  ? 239 ASP   A C   1 
ATOM   188  O O   . ASP   A 1 25  ? 8.51316   -31.36955 -19.93446 1.000 65.46000  ? 239 ASP   A O   1 
ATOM   189  C CB  . ASP   A 1 25  ? 8.68443   -34.83165 -19.57453 1.000 66.93000  ? 239 ASP   A CB  1 
ATOM   190  C CG  . ASP   A 1 25  ? 7.19342   -34.66981 -19.44953 1.000 73.52000  ? 239 ASP   A CG  1 
ATOM   191  O OD1 . ASP   A 1 25  ? 6.57138   -33.96060 -20.28632 1.000 70.95000  ? 239 ASP   A OD1 1 
ATOM   192  O OD2 . ASP   A 1 25  ? 6.64943   -35.24516 -18.47572 1.000 76.81000  ? 239 ASP   A OD2 1 
ATOM   193  N N   . PRO   A 1 26  ? 9.14832   -32.62696 -21.67383 1.000 67.57000  ? 240 PRO   A N   1 
ATOM   194  C CA  . PRO   A 1 26  ? 8.83626   -31.50470 -22.59049 1.000 75.82000  ? 240 PRO   A CA  1 
ATOM   195  C C   . PRO   A 1 26  ? 7.42321   -30.93886 -22.45636 1.000 70.56000  ? 240 PRO   A C   1 
ATOM   196  O O   . PRO   A 1 26  ? 7.22812   -29.72882 -22.62999 1.000 70.67000  ? 240 PRO   A O   1 
ATOM   197  C CB  . PRO   A 1 26  ? 9.08335   -32.10325 -23.98667 1.000 71.72000  ? 240 PRO   A CB  1 
ATOM   198  C CG  . PRO   A 1 26  ? 10.07743  -33.22124 -23.75399 1.000 68.60000  ? 240 PRO   A CG  1 
ATOM   199  C CD  . PRO   A 1 26  ? 9.73244   -33.77969 -22.39117 1.000 68.10000  ? 240 PRO   A CD  1 
ATOM   200  N N   . ASP   A 1 27  ? 6.43227   -31.76103 -22.14364 1.000 67.59000  ? 241 ASP   A N   1 
ATOM   201  C CA  . ASP   A 1 27  ? 5.07822   -31.24319 -22.00753 1.000 71.34000  ? 241 ASP   A CA  1 
ATOM   202  C C   . ASP   A 1 27  ? 4.72414   -30.85266 -20.57741 1.000 66.54000  ? 241 ASP   A C   1 
ATOM   203  O O   . ASP   A 1 27  ? 3.77907   -30.07880 -20.36920 1.000 62.24000  ? 241 ASP   A O   1 
ATOM   204  C CB  . ASP   A 1 27  ? 4.05632   -32.28211 -22.50288 1.000 75.19000  ? 241 ASP   A CB  1 
ATOM   205  C CG  . ASP   A 1 27  ? 3.95037   -32.33865 -24.02490 1.000 81.87000  ? 241 ASP   A CG  1 
ATOM   206  O OD1 . ASP   A 1 27  ? 4.77545   -33.03838 -24.65909 1.000 86.64000  ? 241 ASP   A OD1 1 
ATOM   207  O OD2 . ASP   A 1 27  ? 3.02434   -31.70555 -24.58173 1.000 80.19000  ? 241 ASP   A OD2 1 
ATOM   208  N N   . THR   A 1 28  ? 5.44715   -31.36391 -19.59155 1.000 62.01000  ? 242 THR   A N   1 
ATOM   209  C CA  . THR   A 1 28  ? 4.96611   -31.40337 -18.21858 1.000 62.47000  ? 242 THR   A CA  1 
ATOM   210  C C   . THR   A 1 28  ? 5.79701   -30.49559 -17.32227 1.000 57.78000  ? 242 THR   A C   1 
ATOM   211  O O   . THR   A 1 28  ? 7.02902   -30.59550 -17.28726 1.000 58.93000  ? 242 THR   A O   1 
ATOM   212  C CB  . THR   A 1 28  ? 4.97621   -32.84053 -17.70703 1.000 61.93000  ? 242 THR   A CB  1 
ATOM   213  O OG1 . THR   A 1 28  ? 4.02030   -33.60538 -18.44729 1.000 62.42000  ? 242 THR   A OG1 1 
ATOM   214  C CG2 . THR   A 1 28  ? 4.64317   -32.90701 -16.25106 1.000 64.75000  ? 242 THR   A CG2 1 
ATOM   215  N N   . TYR   A 1 29  ? 5.11592   -29.62087 -16.59602 1.000 53.47000  ? 243 TYR   A N   1 
ATOM   216  C CA  . TYR   A 1 29  ? 5.73882   -28.76413 -15.59973 1.000 61.00000  ? 243 TYR   A CA  1 
ATOM   217  C C   . TYR   A 1 29  ? 5.15480   -29.03761 -14.21184 1.000 54.90000  ? 243 TYR   A C   1 
ATOM   218  O O   . TYR   A 1 29  ? 3.95782   -29.31775 -14.06996 1.000 55.29000  ? 243 TYR   A O   1 
ATOM   219  C CB  . TYR   A 1 29  ? 5.56171   -27.28802 -15.98628 1.000 57.70000  ? 243 TYR   A CB  1 
ATOM   220  C CG  . TYR   A 1 29  ? 6.26672   -26.92456 -17.26814 1.000 59.61000  ? 243 TYR   A CG  1 
ATOM   221  C CD1 . TYR   A 1 29  ? 5.69478   -27.21223 -18.50025 1.000 64.07000  ? 243 TYR   A CD1 1 
ATOM   222  C CD2 . TYR   A 1 29  ? 7.51867   -26.30247 -17.24591 1.000 57.81000  ? 243 TYR   A CD2 1 
ATOM   223  C CE1 . TYR   A 1 29  ? 6.34679   -26.88481 -19.67713 1.000 67.19000  ? 243 TYR   A CE1 1 
ATOM   224  C CE2 . TYR   A 1 29  ? 8.16668   -25.97106 -18.40279 1.000 55.38000  ? 243 TYR   A CE2 1 
ATOM   225  C CZ  . TYR   A 1 29  ? 7.58274   -26.26673 -19.61990 1.000 64.73000  ? 243 TYR   A CZ  1 
ATOM   226  O OH  . TYR   A 1 29  ? 8.22475   -25.94931 -20.79978 1.000 72.44000  ? 243 TYR   A OH  1 
ATOM   227  N N   . SER   A 1 30  ? 5.99776   -28.96586 -13.18479 1.000 57.21000  ? 244 SER   A N   1 
ATOM   228  C CA  . SER   A 1 30  ? 5.54672   -29.05932 -11.80083 1.000 57.23000  ? 244 SER   A CA  1 
ATOM   229  C C   . SER   A 1 30  ? 5.88460   -27.77953 -11.05742 1.000 58.43000  ? 244 SER   A C   1 
ATOM   230  O O   . SER   A 1 30  ? 7.00156   -27.25940 -11.16722 1.000 49.39000  ? 244 SER   A O   1 
ATOM   231  C CB  . SER   A 1 30  ? 6.16380   -30.24251 -11.05818 1.000 57.27000  ? 244 SER   A CB  1 
ATOM   232  O OG  . SER   A 1 30  ? 5.72791   -31.47738 -11.58958 1.000 65.15000  ? 244 SER   A OG  1 
ATOM   233  N N   . LYS   A 1 31  ? 4.92253   -27.27985 -10.28230 1.000 59.89000  ? 245 LYS   A N   1 
ATOM   234  C CA  . LYS   A 1 31  ? 5.13741   -26.05706 -9.53091  1.000 56.64000  ? 245 LYS   A CA  1 
ATOM   235  C C   . LYS   A 1 31  ? 4.83439   -26.30654 -8.06500  1.000 60.72000  ? 245 LYS   A C   1 
ATOM   236  O O   . LYS   A 1 31  ? 3.83443   -26.94373 -7.72923  1.000 67.27000  ? 245 LYS   A O   1 
ATOM   237  C CB  . LYS   A 1 31  ? 4.27634   -24.91696 -10.07558 1.000 53.82000  ? 245 LYS   A CB  1 
ATOM   238  C CG  . LYS   A 1 31  ? 3.95922   -23.88231 -9.02927  1.000 58.11000  ? 245 LYS   A CG  1 
ATOM   239  C CD  . LYS   A 1 31  ? 3.79513   -22.49014 -9.61884  1.000 56.58000  ? 245 LYS   A CD  1 
ATOM   240  C CE  . LYS   A 1 31  ? 3.03317   -22.51980 -10.90787 1.000 55.67000  ? 245 LYS   A CE  1 
ATOM   241  N NZ  . LYS   A 1 31  ? 2.90007   -21.13165 -11.42645 1.000 71.45000  ? 245 LYS   A NZ  1 
ATOM   242  N N   . HIS   A 1 32  ? 5.70732   -25.82874 -7.19482  1.000 62.05000  ? 246 HIS   A N   1 
ATOM   243  C CA  . HIS   A 1 32  ? 5.45528   -25.84921 -5.76783  1.000 56.79000  ? 246 HIS   A CA  1 
ATOM   244  C C   . HIS   A 1 32  ? 5.36415   -24.41237 -5.27639  1.000 52.74000  ? 246 HIS   A C   1 
ATOM   245  O O   . HIS   A 1 32  ? 6.19409   -23.58019 -5.63610  1.000 53.53000  ? 246 HIS   A O   1 
ATOM   246  C CB  . HIS   A 1 32  ? 6.55531   -26.60335 -5.02603  1.000 61.16000  ? 246 HIS   A CB  1 
ATOM   247  C CG  . HIS   A 1 32  ? 6.52225   -26.39181 -3.54897  1.000 66.70000  ? 246 HIS   A CG  1 
ATOM   248  N ND1 . HIS   A 1 32  ? 5.52927   -26.91014 -2.74916  1.000 63.75000  ? 246 HIS   A ND1 1 
ATOM   249  C CD2 . HIS   A 1 32  ? 7.33917   -25.68800 -2.73372  1.000 59.86000  ? 246 HIS   A CD2 1 
ATOM   250  C CE1 . HIS   A 1 32  ? 5.74020   -26.54451 -1.50204  1.000 64.04000  ? 246 HIS   A CE1 1 
ATOM   251  N NE2 . HIS   A 1 32  ? 6.83214   -25.80344 -1.46578  1.000 64.71000  ? 246 HIS   A NE2 1 
ATOM   252  N N   . LEU   A 1 33  ? 4.33910   -24.11070 -4.48533  1.000 55.29000  ? 247 LEU   A N   1 
ATOM   253  C CA  . LEU   A 1 33  ? 4.18997   -22.79090 -3.87792  1.000 52.18000  ? 247 LEU   A CA  1 
ATOM   254  C C   . LEU   A 1 33  ? 4.71593   -22.79130 -2.43890  1.000 54.80000  ? 247 LEU   A C   1 
ATOM   255  O O   . LEU   A 1 33  ? 4.28797   -23.60660 -1.60917  1.000 54.73000  ? 247 LEU   A O   1 
ATOM   256  C CB  . LEU   A 1 33  ? 2.73094   -22.33401 -3.90782  1.000 47.87000  ? 247 LEU   A CB  1 
ATOM   257  C CG  . LEU   A 1 33  ? 1.80800   -22.69572 -5.06897  1.000 50.62000  ? 247 LEU   A CG  1 
ATOM   258  C CD1 . LEU   A 1 33  ? 0.37096   -22.34594 -4.72490  1.000 52.63000  ? 247 LEU   A CD1 1 
ATOM   259  C CD2 . LEU   A 1 33  ? 2.22797   -21.90832 -6.26271  1.000 46.83000  ? 247 LEU   A CD2 1 
ATOM   260  N N   . PHE   A 1 34  ? 5.62384   -21.85632 -2.14059  1.000 50.70000  ? 248 PHE   A N   1 
ATOM   261  C CA  . PHE   A 1 34  ? 6.08678   -21.68472 -0.76552  1.000 50.11000  ? 248 PHE   A CA  1 
ATOM   262  C C   . PHE   A 1 34  ? 5.07769   -20.88605 0.06270   1.000 52.23000  ? 248 PHE   A C   1 
ATOM   263  O O   . PHE   A 1 34  ? 4.70369   -21.29743 1.17156   1.000 49.12000  ? 248 PHE   A O   1 
ATOM   264  C CB  . PHE   A 1 34  ? 7.46173   -20.99661 -0.73426  1.000 45.31000  ? 248 PHE   A CB  1 
ATOM   265  C CG  . PHE   A 1 34  ? 8.52081   -21.65626 -1.60743  1.000 50.43000  ? 248 PHE   A CG  1 
ATOM   266  C CD1 . PHE   A 1 34  ? 9.21489   -22.77334 -1.15776  1.000 51.43000  ? 248 PHE   A CD1 1 
ATOM   267  C CD2 . PHE   A 1 34  ? 8.85880   -21.12484 -2.84826  1.000 48.61000  ? 248 PHE   A CD2 1 
ATOM   268  C CE1 . PHE   A 1 34  ? 10.17296  -23.37502 -1.93492  1.000 47.92000  ? 248 PHE   A CE1 1 
ATOM   269  C CE2 . PHE   A 1 34  ? 9.83488   -21.72152 -3.63141  1.000 47.95000  ? 248 PHE   A CE2 1 
ATOM   270  C CZ  . PHE   A 1 34  ? 10.48395  -22.84961 -3.17474  1.000 52.82000  ? 248 PHE   A CZ  1 
ATOM   271  N N   . VAL   A 1 35  ? 4.66862   -19.71793 -0.44295  1.000 48.35000  ? 249 VAL   A N   1 
ATOM   272  C CA  . VAL   A 1 35  ? 3.70053   -18.85622 0.22629   1.000 50.27000  ? 249 VAL   A CA  1 
ATOM   273  C C   . VAL   A 1 35  ? 2.66452   -18.44498 -0.79562  1.000 49.44000  ? 249 VAL   A C   1 
ATOM   274  O O   . VAL   A 1 35  ? 2.96455   -18.29759 -1.98256  1.000 49.32000  ? 249 VAL   A O   1 
ATOM   275  C CB  . VAL   A 1 35  ? 4.32540   -17.59637 0.87670   1.000 50.61000  ? 249 VAL   A CB  1 
ATOM   276  C CG1 . VAL   A 1 35  ? 5.55641   -17.96152 1.68062   1.000 52.29000  ? 249 VAL   A CG1 1 
ATOM   277  C CG2 . VAL   A 1 35  ? 4.67135   -16.55201 -0.17696  1.000 51.03000  ? 249 VAL   A CG2 1 
ATOM   278  N N   . HIS   A 1 36  ? 1.42850   -18.27623 -0.32660  1.000 52.71000  ? 250 HIS   A N   1 
ATOM   279  C CA  . HIS   A 1 36  ? 0.32350   -17.95904 -1.21554  1.000 54.27000  ? 250 HIS   A CA  1 
ATOM   280  C C   . HIS   A 1 36  ? -0.65160  -17.01833 -0.53128  1.000 49.87000  ? 250 HIS   A C   1 
ATOM   281  O O   . HIS   A 1 36  ? -0.87663  -17.11973 0.67469   1.000 54.10000  ? 250 HIS   A O   1 
ATOM   282  C CB  . HIS   A 1 36  ? -0.41439  -19.22796 -1.66196  1.000 52.91000  ? 250 HIS   A CB  1 
ATOM   283  C CG  . HIS   A 1 36  ? -1.57238  -18.95577 -2.56891  1.000 58.66000  ? 250 HIS   A CG  1 
ATOM   284  N ND1 . HIS   A 1 36  ? -1.41538  -18.44436 -3.83774  1.000 58.44000  ? 250 HIS   A ND1 1 
ATOM   285  C CD2 . HIS   A 1 36  ? -2.90937  -19.08194 -2.37799  1.000 59.27000  ? 250 HIS   A CD2 1 
ATOM   286  C CE1 . HIS   A 1 36  ? -2.60238  -18.28329 -4.39873  1.000 52.73000  ? 250 HIS   A CE1 1 
ATOM   287  N NE2 . HIS   A 1 36  ? -3.52437  -18.66863 -3.53688  1.000 56.71000  ? 250 HIS   A NE2 1 
ATOM   288  N N   . ILE   A 1 37  ? -1.20765  -16.08914 -1.30400  1.000 51.16000  ? 251 ILE   A N   1 
ATOM   289  C CA  . ILE   A 1 37  ? -2.43272  -15.37535 -0.94982  1.000 54.21000  ? 251 ILE   A CA  1 
ATOM   290  C C   . ILE   A 1 37  ? -3.34268  -15.43404 -2.17087  1.000 55.37000  ? 251 ILE   A C   1 
ATOM   291  O O   . ILE   A 1 37  ? -2.98068  -14.92968 -3.24070  1.000 56.86000  ? 251 ILE   A O   1 
ATOM   292  C CB  . ILE   A 1 37  ? -2.17185  -13.91645 -0.54336  1.000 54.44000  ? 251 ILE   A CB  1 
ATOM   293  C CG1 . ILE   A 1 37  ? -1.41689  -13.85880 0.77968   1.000 52.25000  ? 251 ILE   A CG1 1 
ATOM   294  C CG2 . ILE   A 1 37  ? -3.50191  -13.17761 -0.36517  1.000 53.88000  ? 251 ILE   A CG2 1 
ATOM   295  C CD1 . ILE   A 1 37  ? -0.79301  -12.49784 1.07513   1.000 47.30000  ? 251 ILE   A CD1 1 
ATOM   296  N N   . GLY   A 1 38  ? -4.50163  -16.06418 -2.03010  1.000 55.00000  ? 252 GLY   A N   1 
ATOM   297  C CA  . GLY   A 1 38  ? -5.40458  -16.26690 -3.14619  1.000 57.49000  ? 252 GLY   A CA  1 
ATOM   298  C C   . GLY   A 1 38  ? -6.53266  -15.24900 -3.13091  1.000 67.16000  ? 252 GLY   A C   1 
ATOM   299  O O   . GLY   A 1 38  ? -7.02972  -14.87437 -2.07081  1.000 73.71000  ? 252 GLY   A O   1 
ATOM   300  N N   . GLN   A 1 39  ? -6.93966  -14.82666 -4.32179  1.000 65.73000  ? 253 GLN   A N   1 
ATOM   301  C CA  . GLN   A 1 39  ? -8.02273  -13.86471 -4.43252  1.000 66.51000  ? 253 GLN   A CA  1 
ATOM   302  C C   . GLN   A 1 39  ? -9.32570  -14.48397 -3.94476  1.000 74.73000  ? 253 GLN   A C   1 
ATOM   303  O O   . GLN   A 1 39  ? -9.78660  -15.50284 -4.47009  1.000 78.00000  ? 253 GLN   A O   1 
ATOM   304  C CB  . GLN   A 1 39  ? -8.13373  -13.38627 -5.87938  1.000 67.94000  ? 253 GLN   A CB  1 
ATOM   305  C CG  . GLN   A 1 39  ? -9.38778  -12.59226 -6.22617  1.000 67.66000  ? 253 GLN   A CG  1 
ATOM   306  C CD  . GLN   A 1 39  ? -9.36078  -12.07881 -7.66601  1.000 69.25000  ? 253 GLN   A CD  1 
ATOM   307  O OE1 . GLN   A 1 39  ? -10.22183 -11.28875 -8.07779  1.000 72.91000  ? 253 GLN   A OE1 1 
ATOM   308  N NE2 . GLN   A 1 39  ? -8.36572  -12.52449 -8.43612  1.000 65.70000  ? 253 GLN   A NE2 1 
ATOM   309  N N   . THR   A 1 40  ? -9.89178  -13.89734 -2.90059  1.000 75.50000  ? 254 THR   A N   1 
ATOM   310  C CA  . THR   A 1 40  ? -11.20076 -14.27960 -2.40075  1.000 74.42000  ? 254 THR   A CA  1 
ATOM   311  C C   . THR   A 1 40  ? -12.06886 -13.03569 -2.34339  1.000 76.77000  ? 254 THR   A C   1 
ATOM   312  O O   . THR   A 1 40  ? -11.56496 -11.92972 -2.12303  1.000 74.40000  ? 254 THR   A O   1 
ATOM   313  C CB  . THR   A 1 40  ? -11.11675 -14.93903 -1.00995  1.000 83.18000  ? 254 THR   A CB  1 
ATOM   314  O OG1 . THR   A 1 40  ? -10.09083 -14.30919 -0.22973  1.000 83.18000  ? 254 THR   A OG1 1 
ATOM   315  C CG2 . THR   A 1 40  ? -10.83163 -16.42796 -1.13641  1.000 82.03000  ? 254 THR   A CG2 1 
ATOM   316  N N   . ASN   A 1 41  ? -13.36784 -13.21472 -2.57349  1.000 83.12000  ? 255 ASN   A N   1 
ATOM   317  C CA  . ASN   A 1 41  ? -14.28294 -12.08783 -2.46017  1.000 85.87000  ? 255 ASN   A CA  1 
ATOM   318  C C   . ASN   A 1 41  ? -14.72500 -11.91532 -1.00613  1.000 85.13000  ? 255 ASN   A C   1 
ATOM   319  O O   . ASN   A 1 41  ? -14.94894 -12.90356 -0.29544  1.000 84.27000  ? 255 ASN   A O   1 
ATOM   320  C CB  . ASN   A 1 41  ? -15.50989 -12.28065 -3.35126  1.000 88.76000  ? 255 ASN   A CB  1 
ATOM   321  C CG  . ASN   A 1 41  ? -15.64895 -11.18434 -4.40293  1.000 90.83000  ? 255 ASN   A CG  1 
ATOM   322  O OD1 . ASN   A 1 41  ? -14.69400 -10.45817 -4.70567  1.000 82.84000  ? 255 ASN   A OD1 1 
ATOM   323  N ND2 . ASN   A 1 41  ? -16.86795 -11.01428 -4.90791  1.000 92.28000  ? 255 ASN   A ND2 1 
ATOM   324  N N   . PRO   A 1 42  ? -14.86211 -10.68148 -0.53775  1.000 83.86000  ? 256 PRO   A N   1 
ATOM   325  C CA  . PRO   A 1 42  ? -15.28117 -10.47494 0.85131   1.000 86.14000  ? 256 PRO   A CA  1 
ATOM   326  C C   . PRO   A 1 42  ? -16.72214 -10.92412 1.05012   1.000 86.29000  ? 256 PRO   A C   1 
ATOM   327  O O   . PRO   A 1 42  ? -17.58313 -10.73192 0.18715   1.000 87.84000  ? 256 PRO   A O   1 
ATOM   328  C CB  . PRO   A 1 42  ? -15.12130 -8.95999  1.04778   1.000 84.56000  ? 256 PRO   A CB  1 
ATOM   329  C CG  . PRO   A 1 42  ? -15.23430 -8.39057  -0.32004  1.000 82.38000  ? 256 PRO   A CG  1 
ATOM   330  C CD  . PRO   A 1 42  ? -14.60519 -9.40724  -1.23234  1.000 81.45000  ? 256 PRO   A CD  1 
ATOM   331  N N   . ALA   A 1 43  ? -16.97412 -11.55750 2.19492   1.000 77.83000  ? 257 ALA   A N   1 
ATOM   332  C CA  . ALA   A 1 43  ? -18.31110 -12.00072 2.56474   1.000 76.97000  ? 257 ALA   A CA  1 
ATOM   333  C C   . ALA   A 1 43  ? -18.86921 -11.09310 3.65200   1.000 83.36000  ? 257 ALA   A C   1 
ATOM   334  O O   . ALA   A 1 43  ? -18.12327 -10.62431 4.51917   1.000 84.67000  ? 257 ALA   A O   1 
ATOM   335  C CB  . ALA   A 1 43  ? -18.30700 -13.44987 3.05629   1.000 70.91000  ? 257 ALA   A CB  1 
ATOM   336  N N   . PHE   A 1 44  ? -20.18923 -10.84619 3.60004   1.000 79.49000  ? 258 PHE   A N   1 
ATOM   337  C CA  . PHE   A 1 44  ? -20.81433 -10.00156 4.61628   1.000 73.17000  ? 258 PHE   A CA  1 
ATOM   338  C C   . PHE   A 1 44  ? -20.60932 -10.57098 6.01111   1.000 74.92000  ? 258 PHE   A C   1 
ATOM   339  O O   . PHE   A 1 44  ? -20.37241 -9.81726  6.96235   1.000 73.12000  ? 258 PHE   A O   1 
ATOM   340  C CB  . PHE   A 1 44  ? -22.30733 -9.81859  4.32029   1.000 68.93000  ? 258 PHE   A CB  1 
ATOM   341  C CG  . PHE   A 1 44  ? -22.83545 -8.48577  4.76069   1.000 70.63000  ? 258 PHE   A CG  1 
ATOM   342  C CD1 . PHE   A 1 44  ? -22.77052 -7.37850  3.91504   1.000 70.56000  ? 258 PHE   A CD1 1 
ATOM   343  C CD2 . PHE   A 1 44  ? -23.33851 -8.31821  6.04973   1.000 69.83000  ? 258 PHE   A CD2 1 
ATOM   344  C CE1 . PHE   A 1 44  ? -23.22463 -6.12867  4.33641   1.000 70.18000  ? 258 PHE   A CE1 1 
ATOM   345  C CE2 . PHE   A 1 44  ? -23.79762 -7.07539  6.49110   1.000 69.20000  ? 258 PHE   A CE2 1 
ATOM   346  C CZ  . PHE   A 1 44  ? -23.74468 -5.97711  5.63044   1.000 72.79000  ? 258 PHE   A CZ  1 
ATOM   347  N N   . SER   A 1 45  ? -20.62522 -11.88901 6.11370   1.000 75.99000  ? 259 SER   A N   1 
ATOM   348  C CA  . SER   A 1 45  ? -20.49421 -12.56040 7.39649   1.000 75.68000  ? 259 SER   A CA  1 
ATOM   349  C C   . SER   A 1 45  ? -19.09622 -12.63947 7.97051   1.000 85.27000  ? 259 SER   A C   1 
ATOM   350  O O   . SER   A 1 45  ? -18.90320 -13.21378 9.03534   1.000 85.95000  ? 259 SER   A O   1 
ATOM   351  C CB  . SER   A 1 45  ? -20.98308 -13.98738 7.19503   1.000 69.62000  ? 259 SER   A CB  1 
ATOM   352  O OG  . SER   A 1 45  ? -20.66505 -14.81869 8.29479   1.000 90.81000  ? 259 SER   A OG  1 
ATOM   353  N N   . ASP   A 1 46  ? -18.11424 -12.06318 7.30372   1.000 81.83000  ? 260 ASP   A N   1 
ATOM   354  C CA  . ASP   A 1 46  ? -16.72424 -12.22621 7.75772   1.000 82.77000  ? 260 ASP   A CA  1 
ATOM   355  C C   . ASP   A 1 46  ? -16.35236 -11.23552 8.86704   1.000 83.92000  ? 260 ASP   A C   1 
ATOM   356  O O   . ASP   A 1 46  ? -16.76945 -10.06055 8.83539   1.000 82.25000  ? 260 ASP   A O   1 
ATOM   357  C CB  . ASP   A 1 46  ? -15.78022 -12.03976 6.57580   1.000 84.12000  ? 260 ASP   A CB  1 
ATOM   358  C CG  . ASP   A 1 46  ? -15.75810 -13.25448 5.66843   1.000 83.34000  ? 260 ASP   A CG  1 
ATOM   359  O OD1 . ASP   A 1 46  ? -16.10202 -14.34367 6.19708   1.000 88.92000  ? 260 ASP   A OD1 1 
ATOM   360  O OD2 . ASP   A 1 46  ? -15.42007 -13.14309 4.48747   1.000 82.56000  ? 260 ASP   A OD2 1 
ATOM   361  N N   . PRO   A 1 47  ? -15.51736 -11.62576 9.83594   1.000 84.44000  ? 261 PRO   A N   1 
ATOM   362  C CA  . PRO   A 1 47  ? -15.22646 -10.72608 10.94023  1.000 76.52000  ? 261 PRO   A CA  1 
ATOM   363  C C   . PRO   A 1 47  ? -14.08153 -9.80187  10.56155  1.000 79.76000  ? 261 PRO   A C   1 
ATOM   364  O O   . PRO   A 1 47  ? -13.17947 -10.15955 9.77747   1.000 78.19000  ? 261 PRO   A O   1 
ATOM   365  C CB  . PRO   A 1 47  ? -14.80842 -11.66340 12.08195  1.000 73.03000  ? 261 PRO   A CB  1 
ATOM   366  C CG  . PRO   A 1 47  ? -14.32430 -12.96114 11.37156  1.000 73.74000  ? 261 PRO   A CG  1 
ATOM   367  C CD  . PRO   A 1 47  ? -14.58927 -12.76370 9.89761   1.000 84.83000  ? 261 PRO   A CD  1 
ATOM   368  N N   . PRO   A 1 48  ? -14.11564 -8.53802  11.03795  1.000 81.20000  ? 262 PRO   A N   1 
ATOM   369  C CA  . PRO   A 1 48  ? -13.05972 -7.54685  10.76529  1.000 80.11000  ? 262 PRO   A CA  1 
ATOM   370  C C   . PRO   A 1 48  ? -11.68768 -8.10484  11.10216  1.000 75.38000  ? 262 PRO   A C   1 
ATOM   371  O O   . PRO   A 1 48  ? -11.54764 -8.94711  12.00390  1.000 72.48000  ? 262 PRO   A O   1 
ATOM   372  C CB  . PRO   A 1 48  ? -13.44784 -6.35816  11.66964  1.000 72.73000  ? 262 PRO   A CB  1 
ATOM   373  C CG  . PRO   A 1 48  ? -14.78683 -6.64545  12.23951  1.000 75.11000  ? 262 PRO   A CG  1 
ATOM   374  C CD  . PRO   A 1 48  ? -15.20471 -8.02036  11.86507  1.000 81.18000  ? 262 PRO   A CD  1 
ATOM   375  N N   . LEU   A 1 49  ? -10.69169 -7.65053  10.35433  1.000 68.18000  ? 263 LEU   A N   1 
ATOM   376  C CA  . LEU   A 1 49  ? -9.32467  -8.05250  10.62225  1.000 64.13000  ? 263 LEU   A CA  1 
ATOM   377  C C   . LEU   A 1 49  ? -8.87775  -7.55589  11.98341  1.000 67.28000  ? 263 LEU   A C   1 
ATOM   378  O O   . LEU   A 1 49  ? -9.14886  -6.41703  12.37676  1.000 67.01000  ? 263 LEU   A O   1 
ATOM   379  C CB  . LEU   A 1 49  ? -8.37268  -7.51710  9.56544   1.000 64.66000  ? 263 LEU   A CB  1 
ATOM   380  C CG  . LEU   A 1 49  ? -8.82862  -7.66469  8.12938   1.000 72.06000  ? 263 LEU   A CG  1 
ATOM   381  C CD1 . LEU   A 1 49  ? -8.23269  -6.52739  7.32975   1.000 73.09000  ? 263 LEU   A CD1 1 
ATOM   382  C CD2 . LEU   A 1 49  ? -8.39650  -9.02949  7.60597   1.000 60.03000  ? 263 LEU   A CD2 1 
ATOM   383  N N   . GLU   A 1 50  ? -8.18571  -8.42706  12.70516  1.000 67.84000  ? 264 GLU   A N   1 
ATOM   384  C CA  . GLU   A 1 50  ? -7.60878  -8.03341  13.97031  1.000 64.15000  ? 264 GLU   A CA  1 
ATOM   385  C C   . GLU   A 1 50  ? -6.53085  -6.98125  13.75267  1.000 69.38000  ? 264 GLU   A C   1 
ATOM   386  O O   . GLU   A 1 50  ? -5.96983  -6.82987  12.65673  1.000 64.12000  ? 264 GLU   A O   1 
ATOM   387  C CB  . GLU   A 1 50  ? -7.04070  -9.25158  14.68694  1.000 62.00000  ? 264 GLU   A CB  1 
ATOM   388  C CG  . GLU   A 1 50  ? -7.88460  -10.46557 14.43754  1.000 72.49000  ? 264 GLU   A CG  1 
ATOM   389  C CD  . GLU   A 1 50  ? -7.19650  -11.74164 14.82316  1.000 79.12000  ? 264 GLU   A CD  1 
ATOM   390  O OE1 . GLU   A 1 50  ? -6.66353  -11.80695 15.95416  1.000 82.87000  ? 264 GLU   A OE1 1 
ATOM   391  O OE2 . GLU   A 1 50  ? -7.18840  -12.67438 13.98587  1.000 79.51000  ? 264 GLU   A OE2 1 
ATOM   392  N N   . ALA   A 1 51  ? -6.24495  -6.24056  14.81691  1.000 68.11000  ? 265 ALA   A N   1 
ATOM   393  C CA  . ALA   A 1 51  ? -5.30604  -5.13447  14.76428  1.000 64.87000  ? 265 ALA   A CA  1 
ATOM   394  C C   . ALA   A 1 51  ? -4.00903  -5.52758  15.45420  1.000 62.80000  ? 265 ALA   A C   1 
ATOM   395  O O   . ALA   A 1 51  ? -4.02601  -6.17291  16.51000  1.000 63.65000  ? 265 ALA   A O   1 
ATOM   396  C CB  . ALA   A 1 51  ? -5.90316  -3.88071  15.40165  1.000 61.09000  ? 265 ALA   A CB  1 
ATOM   397  N N   . VAL   A 1 52  ? -2.89604  -5.15629  14.83135  1.000 58.46000  ? 266 VAL   A N   1 
ATOM   398  C CA  . VAL   A 1 52  ? -1.56404  -5.27736  15.39735  1.000 51.55000  ? 266 VAL   A CA  1 
ATOM   399  C C   . VAL   A 1 52  ? -0.93716  -3.89431  15.39880  1.000 60.94000  ? 266 VAL   A C   1 
ATOM   400  O O   . VAL   A 1 52  ? -0.83717  -3.24998  14.34401  1.000 54.53000  ? 266 VAL   A O   1 
ATOM   401  C CB  . VAL   A 1 52  ? -0.68994  -6.26105  14.60707  1.000 47.11000  ? 266 VAL   A CB  1 
ATOM   402  C CG1 . VAL   A 1 52  ? 0.72004   -6.23810  15.14112  1.000 52.61000  ? 266 VAL   A CG1 1 
ATOM   403  C CG2 . VAL   A 1 52  ? -1.25783  -7.65012  14.70862  1.000 47.73000  ? 266 VAL   A CG2 1 
ATOM   404  N N   . ASP   A 1 53  ? -0.52323  -3.43865  16.58296  1.000 62.95000  ? 267 ASP   A N   1 
ATOM   405  C CA  . ASP   A 1 53  ? 0.14766   -2.15363  16.71638  1.000 60.91000  ? 267 ASP   A CA  1 
ATOM   406  C C   . ASP   A 1 53  ? 1.40569   -2.09727  15.85443  1.000 59.22000  ? 267 ASP   A C   1 
ATOM   407  O O   . ASP   A 1 53  ? 2.25676   -2.99121  15.90818  1.000 55.22000  ? 267 ASP   A O   1 
ATOM   408  C CB  . ASP   A 1 53  ? 0.50760   -1.90106  18.17347  1.000 64.43000  ? 267 ASP   A CB  1 
ATOM   409  C CG  . ASP   A 1 53  ? 0.70747   -0.43513  18.46693  1.000 69.45000  ? 267 ASP   A CG  1 
ATOM   410  O OD1 . ASP   A 1 53  ? -0.06458  0.40697   17.93917  1.000 72.84000  ? 267 ASP   A OD1 1 
ATOM   411  O OD2 . ASP   A 1 53  ? 1.67642   -0.12528  19.18606  1.000 67.96000  ? 267 ASP   A OD2 1 
ATOM   412  N N   . VAL   A 1 54  ? 1.52062   -1.02901  15.06477  1.000 57.43000  ? 268 VAL   A N   1 
ATOM   413  C CA  . VAL   A 1 54  ? 2.66364   -0.89564  14.17885  1.000 55.45000  ? 268 VAL   A CA  1 
ATOM   414  C C   . VAL   A 1 54  ? 3.94160   -0.69779  14.97895  1.000 62.87000  ? 268 VAL   A C   1 
ATOM   415  O O   . VAL   A 1 54  ? 5.01765   -1.14057  14.55684  1.000 66.03000  ? 268 VAL   A O   1 
ATOM   416  C CB  . VAL   A 1 54  ? 2.41858   0.23465   13.16519  1.000 55.24000  ? 268 VAL   A CB  1 
ATOM   417  C CG1 . VAL   A 1 54  ? 2.36845   1.56544   13.84460  1.000 57.08000  ? 268 VAL   A CG1 1 
ATOM   418  C CG2 . VAL   A 1 54  ? 3.52261   0.23308   12.09123  1.000 59.87000  ? 268 VAL   A CG2 1 
ATOM   419  N N   . ARG   A 1 55  ? 3.85051   -0.07116  16.15514  1.000 64.26000  ? 269 ARG   A N   1 
ATOM   420  C CA  . ARG   A 1 55  ? 5.04147   0.13268   16.97024  1.000 60.93000  ? 269 ARG   A CA  1 
ATOM   421  C C   . ARG   A 1 55  ? 5.67956   -1.19039  17.37585  1.000 65.30000  ? 269 ARG   A C   1 
ATOM   422  O O   . ARG   A 1 55  ? 6.91057   -1.27433  17.50186  1.000 69.73000  ? 269 ARG   A O   1 
ATOM   423  C CB  . ARG   A 1 55  ? 4.69136   0.98327   18.19350  1.000 62.79000  ? 269 ARG   A CB  1 
ATOM   424  C CG  . ARG   A 1 55  ? 4.08627   2.32934   17.83090  1.000 60.21000  ? 269 ARG   A CG  1 
ATOM   425  C CD  . ARG   A 1 55  ? 2.74823   2.52802   18.51092  1.000 66.12000  ? 269 ARG   A CD  1 
ATOM   426  N NE  . ARG   A 1 55  ? 2.30211   3.91295   18.59333  1.000 70.84000  ? 269 ARG   A NE  1 
ATOM   427  C CZ  . ARG   A 1 55  ? 1.11407   4.27471   19.06341  1.000 73.17000  ? 269 ARG   A CZ  1 
ATOM   428  N NH1 . ARG   A 1 55  ? 0.27213   3.38549   19.56311  1.000 74.46000  ? 269 ARG   A NH1 1 
ATOM   429  N NH2 . ARG   A 1 55  ? 0.72397   5.54372   18.95079  1.000 65.28000  ? 269 ARG   A NH2 1 
ATOM   430  N N   . GLN   A 1 56  ? 4.87564   -2.24251  17.54950  1.000 61.82000  ? 270 GLN   A N   1 
ATOM   431  C CA  . GLN   A 1 56  ? 5.43673   -3.51461  17.99212  1.000 65.54000  ? 270 GLN   A CA  1 
ATOM   432  C C   . GLN   A 1 56  ? 6.33782   -4.14920  16.93695  1.000 63.03000  ? 270 GLN   A C   1 
ATOM   433  O O   . GLN   A 1 56  ? 7.24387   -4.91124  17.28874  1.000 67.37000  ? 270 GLN   A O   1 
ATOM   434  C CB  . GLN   A 1 56  ? 4.32280   -4.48982  18.38078  1.000 64.29000  ? 270 GLN   A CB  1 
ATOM   435  C CG  . GLN   A 1 56  ? 3.27873   -3.92919  19.31492  1.000 65.34000  ? 270 GLN   A CG  1 
ATOM   436  C CD  . GLN   A 1 56  ? 3.80567   -3.77759  20.74099  1.000 82.52000  ? 270 GLN   A CD  1 
ATOM   437  O OE1 . GLN   A 1 56  ? 3.87856   -2.66475  21.26833  1.000 79.95000  ? 270 GLN   A OE1 1 
ATOM   438  N NE2 . GLN   A 1 56  ? 4.18774   -4.89976  21.36665  1.000 74.94000  ? 270 GLN   A NE2 1 
ATOM   439  N N   . ILE   A 1 57  ? 6.12083   -3.86982  15.65003  1.000 60.97000  ? 271 ILE   A N   1 
ATOM   440  C CA  . ILE   A 1 57  ? 6.92992   -4.52144  14.62185  1.000 63.78000  ? 271 ILE   A CA  1 
ATOM   441  C C   . ILE   A 1 57  ? 7.95386   -3.58716  13.99117  1.000 63.62000  ? 271 ILE   A C   1 
ATOM   442  O O   . ILE   A 1 57  ? 8.63393   -3.99481  13.04007  1.000 59.81000  ? 271 ILE   A O   1 
ATOM   443  C CB  . ILE   A 1 57  ? 6.06400   -5.13516  13.50663  1.000 62.58000  ? 271 ILE   A CB  1 
ATOM   444  C CG1 . ILE   A 1 57  ? 5.30094   -4.03899  12.77995  1.000 62.29000  ? 271 ILE   A CG1 1 
ATOM   445  C CG2 . ILE   A 1 57  ? 5.06807   -6.12742  14.09729  1.000 59.02000  ? 271 ILE   A CG2 1 
ATOM   446  C CD1 . ILE   A 1 57  ? 4.76902   -4.47462  11.42780  1.000 62.68000  ? 271 ILE   A CD1 1 
ATOM   447  N N   . TYR   A 1 58  ? 8.08075   -2.34630  14.48156  1.000 64.98000  ? 272 TYR   A N   1 
ATOM   448  C CA  . TYR   A 1 58  ? 9.09169   -1.42506  13.96788  1.000 59.46000  ? 272 TYR   A CA  1 
ATOM   449  C C   . TYR   A 1 58  ? 10.46774  -2.07392  13.89672  1.000 59.22000  ? 272 TYR   A C   1 
ATOM   450  O O   . TYR   A 1 58  ? 11.17976  -1.92456  12.90479  1.000 66.06000  ? 272 TYR   A O   1 
ATOM   451  C CB  . TYR   A 1 58  ? 9.17856   -0.18132  14.84427  1.000 64.00000  ? 272 TYR   A CB  1 
ATOM   452  C CG  . TYR   A 1 58  ? 8.12248   0.86965   14.65157  1.000 64.19000  ? 272 TYR   A CG  1 
ATOM   453  C CD1 . TYR   A 1 58  ? 7.31552   0.88193   13.53455  1.000 67.69000  ? 272 TYR   A CD1 1 
ATOM   454  C CD2 . TYR   A 1 58  ? 7.97237   1.89235   15.58088  1.000 60.11000  ? 272 TYR   A CD2 1 
ATOM   455  C CE1 . TYR   A 1 58  ? 6.35644   1.87491   13.36282  1.000 64.89000  ? 272 TYR   A CE1 1 
ATOM   456  C CE2 . TYR   A 1 58  ? 7.03630   2.88833   15.41016  1.000 60.00000  ? 272 TYR   A CE2 1 
ATOM   457  C CZ  . TYR   A 1 58  ? 6.22333   2.87361   14.30613  1.000 62.38000  ? 272 TYR   A CZ  1 
ATOM   458  O OH  . TYR   A 1 58  ? 5.27926   3.86258   14.13941  1.000 67.37000  ? 272 TYR   A OH  1 
ATOM   459  N N   . ASP   A 1 59  ? 10.85877  -2.80722  14.94051  1.000 57.16000  ? 273 ASP   A N   1 
ATOM   460  C CA  . ASP   A 1 59  ? 12.22381  -3.32113  15.00339  1.000 59.19000  ? 273 ASP   A CA  1 
ATOM   461  C C   . ASP   A 1 59  ? 12.49193  -4.40678  13.96106  1.000 58.21000  ? 273 ASP   A C   1 
ATOM   462  O O   . ASP   A 1 59  ? 13.65096  -4.63858  13.60902  1.000 63.57000  ? 273 ASP   A O   1 
ATOM   463  C CB  . ASP   A 1 59  ? 12.50481  -3.88753  16.38622  1.000 57.39000  ? 273 ASP   A CB  1 
ATOM   464  C CG  . ASP   A 1 59  ? 11.55389  -5.00672  16.72884  1.000 67.35000  ? 273 ASP   A CG  1 
ATOM   465  O OD1 . ASP   A 1 59  ? 10.33889  -4.89272  16.40884  1.000 65.47000  ? 273 ASP   A OD1 1 
ATOM   466  O OD2 . ASP   A 1 59  ? 12.02996  -6.02185  17.27554  1.000 72.99000  ? 273 ASP   A OD2 1 
ATOM   467  N N   . LYS   A 1 60  ? 11.45600  -5.10872  13.48881  1.000 53.44000  ? 274 LYS   A N   1 
ATOM   468  C CA  . LYS   A 1 60  ? 11.64512  -6.17940  12.51748  1.000 53.31000  ? 274 LYS   A CA  1 
ATOM   469  C C   . LYS   A 1 60  ? 11.87512  -5.65294  11.10465  1.000 58.06000  ? 274 LYS   A C   1 
ATOM   470  O O   . LYS   A 1 60  ? 12.28721  -6.41564  10.22743  1.000 57.75000  ? 274 LYS   A O   1 
ATOM   471  C CB  . LYS   A 1 60  ? 10.43619  -7.11249  12.49915  1.000 53.08000  ? 274 LYS   A CB  1 
ATOM   472  C CG  . LYS   A 1 60  ? 9.86618   -7.42896  13.86304  1.000 63.43000  ? 274 LYS   A CG  1 
ATOM   473  C CD  . LYS   A 1 60  ? 8.73626   -8.44202  13.76169  1.000 62.18000  ? 274 LYS   A CD  1 
ATOM   474  C CE  . LYS   A 1 60  ? 9.23639   -9.73679  13.13330  1.000 61.47000  ? 274 LYS   A CE  1 
ATOM   475  N NZ  . LYS   A 1 60  ? 10.42540  -10.21193 13.89619  1.000 65.00000  ? 274 LYS   A NZ  1 
ATOM   476  N N   . PHE   A 1 61  ? 11.63502  -4.38089  10.88904  1.000 60.64000  ? 275 PHE   A N   1 
ATOM   477  C CA  . PHE   A 1 61  ? 11.88802  -3.79647  9.60023   1.000 58.16000  ? 275 PHE   A CA  1 
ATOM   478  C C   . PHE   A 1 61  ? 12.80792  -2.61447  9.82963   1.000 58.33000  ? 275 PHE   A C   1 
ATOM   479  O O   . PHE   A 1 61  ? 12.97284  -2.17180  10.94877  1.000 63.48000  ? 275 PHE   A O   1 
ATOM   480  C CB  . PHE   A 1 61  ? 10.56001  -3.40338  8.95931   1.000 60.08000  ? 275 PHE   A CB  1 
ATOM   481  C CG  . PHE   A 1 61  ? 9.62911   -4.55739  8.76192   1.000 52.72000  ? 275 PHE   A CG  1 
ATOM   482  C CD1 . PHE   A 1 61  ? 9.68120   -5.31003  7.60769   1.000 51.51000  ? 275 PHE   A CD1 1 
ATOM   483  C CD2 . PHE   A 1 61  ? 8.71710   -4.90177  9.73979   1.000 54.54000  ? 275 PHE   A CD2 1 
ATOM   484  C CE1 . PHE   A 1 61  ? 8.83129   -6.37804  7.42333   1.000 50.38000  ? 275 PHE   A CE1 1 
ATOM   485  C CE2 . PHE   A 1 61  ? 7.86919   -5.97279  9.56343   1.000 55.55000  ? 275 PHE   A CE2 1 
ATOM   486  C CZ  . PHE   A 1 61  ? 7.92729   -6.71342  8.40420   1.000 48.46000  ? 275 PHE   A CZ  1 
ATOM   487  N N   . PRO   A 1 62  ? 13.44391  -2.11709  8.78180   1.000 60.89000  ? 276 PRO   A N   1 
ATOM   488  C CA  . PRO   A 1 62  ? 14.40481  -1.03508  8.98917   1.000 65.63000  ? 276 PRO   A CA  1 
ATOM   489  C C   . PRO   A 1 62  ? 13.71070  0.21471   9.48454   1.000 66.46000  ? 276 PRO   A C   1 
ATOM   490  O O   . PRO   A 1 62  ? 12.59669  0.48275   9.06859   1.000 67.48000  ? 276 PRO   A O   1 
ATOM   491  C CB  . PRO   A 1 62  ? 15.01384  -0.83060  7.60425   1.000 56.57000  ? 276 PRO   A CB  1 
ATOM   492  C CG  . PRO   A 1 62  ? 14.74297  -2.09739  6.87085   1.000 63.93000  ? 276 PRO   A CG  1 
ATOM   493  C CD  . PRO   A 1 62  ? 13.42299  -2.57366  7.38566   1.000 70.91000  ? 276 PRO   A CD  1 
ATOM   494  N N   . GLU   A 1 63  ? 14.35561  0.97849   10.34880  1.000 67.17000  ? 277 GLU   A N   1 
ATOM   495  C CA  . GLU   A 1 63  ? 13.70350  2.12925   10.95713  1.000 74.49000  ? 277 GLU   A CA  1 
ATOM   496  C C   . GLU   A 1 63  ? 14.57341  3.29740   10.69252  1.000 75.58000  ? 277 GLU   A C   1 
ATOM   497  O O   . GLU   A 1 63  ? 15.36635  3.68921   11.53667  1.000 82.38000  ? 277 GLU   A O   1 
ATOM   498  C CB  . GLU   A 1 63  ? 13.52947  1.93477   12.45507  1.000 78.20000  ? 277 GLU   A CB  1 
ATOM   499  C CG  . GLU   A 1 63  ? 13.22757  0.50861   12.88561  1.000 76.11000  ? 277 GLU   A CG  1 
ATOM   500  C CD  . GLU   A 1 63  ? 14.48363  -0.31136  13.12540  1.000 77.23000  ? 277 GLU   A CD  1 
ATOM   501  O OE1 . GLU   A 1 63  ? 15.58458  0.27673   13.13462  1.000 77.63000  ? 277 GLU   A OE1 1 
ATOM   502  O OE2 . GLU   A 1 63  ? 14.37372  -1.54043  13.30901  1.000 73.35000  ? 277 GLU   A OE2 1 
ATOM   503  N N   . LYS   A 1 64  ? 14.43140  3.86576   9.52270   1.000 70.17000  ? 278 LYS   A N   1 
ATOM   504  C CA  . LYS   A 1 64  ? 15.27633  4.92396   9.07605   1.000 70.58000  ? 278 LYS   A CA  1 
ATOM   505  C C   . LYS   A 1 64  ? 14.37531  5.54720   8.08022   1.000 76.16000  ? 278 LYS   A C   1 
ATOM   506  O O   . LYS   A 1 64  ? 13.24335  5.12916   7.91805   1.000 79.35000  ? 278 LYS   A O   1 
ATOM   507  C CB  . LYS   A 1 64  ? 16.51639  4.40128   8.38693   1.000 75.58000  ? 278 LYS   A CB  1 
ATOM   508  C CG  . LYS   A 1 64  ? 17.43144  3.53209   9.23469   1.000 79.26000  ? 278 LYS   A CG  1 
ATOM   509  C CD  . LYS   A 1 64  ? 18.57235  4.32499   9.85597   1.000 82.72000  ? 278 LYS   A CD  1 
ATOM   510  C CE  . LYS   A 1 64  ? 18.11225  5.21560   10.99823  1.000 82.29000  ? 278 LYS   A CE  1 
ATOM   511  N NZ  . LYS   A 1 64  ? 19.25317  5.92449   11.63449  1.000 77.82000  ? 278 LYS   A NZ  1 
ATOM   512  N N   . LYS   A 1 65  ? 14.82425  6.58944   7.42856   1.000 82.14000  ? 279 LYS   A N   1 
ATOM   513  C CA  . LYS   A 1 65  ? 13.98724  7.12669   6.40070   1.000 81.78000  ? 279 LYS   A CA  1 
ATOM   514  C C   . LYS   A 1 65  ? 13.76036  6.00997   5.44334   1.000 78.18000  ? 279 LYS   A C   1 
ATOM   515  O O   . LYS   A 1 65  ? 14.67043  5.25614   5.12714   1.000 73.73000  ? 279 LYS   A O   1 
ATOM   516  C CB  . LYS   A 1 65  ? 14.71817  8.23997   5.69207   1.000 84.08000  ? 279 LYS   A CB  1 
ATOM   517  C CG  . LYS   A 1 65  ? 13.87013  9.07919   4.76130   1.000 87.68000  ? 279 LYS   A CG  1 
ATOM   518  C CD  . LYS   A 1 65  ? 14.68605  10.26041  4.26469   1.000 93.26000  ? 279 LYS   A CD  1 
ATOM   519  C CE  . LYS   A 1 65  ? 15.42496  10.91511  5.41992   1.000 97.11000  ? 279 LYS   A CE  1 
ATOM   520  N NZ  . LYS   A 1 65  ? 16.41989  11.91534  4.94726   1.000 86.07000  ? 279 LYS   A NZ  1 
ATOM   521  N N   . GLY   A 1 66  ? 12.53338  5.89102   4.96327   1.000 79.51000  ? 280 GLY   A N   1 
ATOM   522  C CA  . GLY   A 1 66  ? 12.18650  4.74925   4.14090   1.000 76.44000  ? 280 GLY   A CA  1 
ATOM   523  C C   . GLY   A 1 66  ? 11.82256  3.60894   5.05753   1.000 78.16000  ? 280 GLY   A C   1 
ATOM   524  O O   . GLY   A 1 66  ? 11.57167  2.49306   4.60818   1.000 74.67000  ? 280 GLY   A O   1 
ATOM   525  N N   . GLY   A 1 67  ? 11.77950  3.88753   6.35162   1.000 73.71000  ? 281 GLY   A N   1 
ATOM   526  C CA  . GLY   A 1 67  ? 11.39855  2.87420   7.31429   1.000 74.57000  ? 281 GLY   A CA  1 
ATOM   527  C C   . GLY   A 1 67  ? 9.91555   2.79301   7.53122   1.000 68.82000  ? 281 GLY   A C   1 
ATOM   528  O O   . GLY   A 1 67  ? 9.16250   3.57812   6.98044   1.000 68.66000  ? 281 GLY   A O   1 
ATOM   529  N N   . LEU   A 1 68  ? 9.48860   1.87572   8.37492   1.000 60.53000  ? 282 LEU   A N   1 
ATOM   530  C CA  . LEU   A 1 68  ? 8.05861   1.66756   8.51581   1.000 61.64000  ? 282 LEU   A CA  1 
ATOM   531  C C   . LEU   A 1 68  ? 7.40749   2.81327   9.27615   1.000 64.95000  ? 282 LEU   A C   1 
ATOM   532  O O   . LEU   A 1 68  ? 6.30747   3.25429   8.92325   1.000 66.14000  ? 282 LEU   A O   1 
ATOM   533  C CB  . LEU   A 1 68  ? 7.81370   0.32733   9.19439   1.000 57.94000  ? 282 LEU   A CB  1 
ATOM   534  C CG  . LEU   A 1 68  ? 6.36973   -0.11982  9.28420   1.000 56.16000  ? 282 LEU   A CG  1 
ATOM   535  C CD1 . LEU   A 1 68  ? 5.72475   0.11754   7.95726   1.000 57.20000  ? 282 LEU   A CD1 1 
ATOM   536  C CD2 . LEU   A 1 68  ? 6.37184   -1.59591  9.56374   1.000 56.74000  ? 282 LEU   A CD2 1 
ATOM   537  N N   . LYS   A 1 69  ? 8.08842   3.33200   10.29833  1.000 67.07000  ? 283 LYS   A N   1 
ATOM   538  C CA  . LYS   A 1 69  ? 7.56231   4.46173   11.05467  1.000 69.23000  ? 283 LYS   A CA  1 
ATOM   539  C C   . LYS   A 1 69  ? 7.33824   5.66899   10.15204  1.000 70.19000  ? 283 LYS   A C   1 
ATOM   540  O O   . LYS   A 1 69  ? 6.23219   6.22991   10.11118  1.000 67.67000  ? 283 LYS   A O   1 
ATOM   541  C CB  . LYS   A 1 69  ? 8.51624   4.81645   12.20181  1.000 74.03000  ? 283 LYS   A CB  1 
ATOM   542  C CG  . LYS   A 1 69  ? 7.84315   5.49702   13.39800  1.000 70.31000  ? 283 LYS   A CG  1 
ATOM   543  C CD  . LYS   A 1 69  ? 8.84808   5.96878   14.42918  1.000 70.47000  ? 283 LYS   A CD  1 
ATOM   544  C CE  . LYS   A 1 69  ? 9.70601   7.08302   13.87155  1.000 77.70000  ? 283 LYS   A CE  1 
ATOM   545  N NZ  . LYS   A 1 69  ? 9.52588   8.32475   14.68793  1.000 80.10000  ? 283 LYS   A NZ  1 
ATOM   546  N N   . GLU   A 1 70  ? 8.38223   6.08330   9.42220   1.000 65.56000  ? 284 GLU   A N   1 
ATOM   547  C CA  . GLU   A 1 70  ? 8.25916   7.23157   8.52555   1.000 68.99000  ? 284 GLU   A CA  1 
ATOM   548  C C   . GLU   A 1 70  ? 7.14721   7.01280   7.50845   1.000 67.20000  ? 284 GLU   A C   1 
ATOM   549  O O   . GLU   A 1 70  ? 6.31215   7.89780   7.28870   1.000 66.34000  ? 284 GLU   A O   1 
ATOM   550  C CB  . GLU   A 1 70  ? 9.59016   7.51190   7.82368   1.000 72.15000  ? 284 GLU   A CB  1 
ATOM   551  C CG  . GLU   A 1 70  ? 10.72910  7.90769   8.76784   1.000 78.32000  ? 284 GLU   A CG  1 
ATOM   552  C CD  . GLU   A 1 70  ? 11.88007  8.59401   8.04509   1.000 82.15000  ? 284 GLU   A CD  1 
ATOM   553  O OE1 . GLU   A 1 70  ? 11.70107  8.99536   6.86821   1.000 82.73000  ? 284 GLU   A OE1 1 
ATOM   554  O OE2 . GLU   A 1 70  ? 12.97904  8.69691   8.64115   1.000 78.14000  ? 284 GLU   A OE2 1 
ATOM   555  N N   . LEU   A 1 71  ? 7.10233   5.83099   6.89008   1.000 63.32000  ? 285 LEU   A N   1 
ATOM   556  C CA  . LEU   A 1 71  ? 5.99938   5.54418   5.98196   1.000 61.97000  ? 285 LEU   A CA  1 
ATOM   557  C C   . LEU   A 1 71  ? 4.66534   5.68885   6.69396   1.000 63.30000  ? 285 LEU   A C   1 
ATOM   558  O O   . LEU   A 1 71  ? 3.77330   6.39793   6.21915   1.000 64.14000  ? 285 LEU   A O   1 
ATOM   559  C CB  . LEU   A 1 71  ? 6.13251   4.14738   5.38452   1.000 62.22000  ? 285 LEU   A CB  1 
ATOM   560  C CG  . LEU   A 1 71  ? 7.08355   4.07582   4.18853   1.000 65.72000  ? 285 LEU   A CG  1 
ATOM   561  C CD1 . LEU   A 1 71  ? 7.52168   2.63295   3.89310   1.000 58.76000  ? 285 LEU   A CD1 1 
ATOM   562  C CD2 . LEU   A 1 71  ? 6.46953   4.75315   2.97172   1.000 59.31000  ? 285 LEU   A CD2 1 
ATOM   563  N N   . TYR   A 1 72  ? 4.52036   5.04148   7.85375   1.000 60.01000  ? 286 TYR   A N   1 
ATOM   564  C CA  . TYR   A 1 72  ? 3.25433   5.10515   8.57473   1.000 62.42000  ? 286 TYR   A CA  1 
ATOM   565  C C   . TYR   A 1 72  ? 2.89820   6.53500   8.95517   1.000 62.98000  ? 286 TYR   A C   1 
ATOM   566  O O   . TYR   A 1 72  ? 1.71917   6.90590   8.97725   1.000 61.13000  ? 286 TYR   A O   1 
ATOM   567  C CB  . TYR   A 1 72  ? 3.29136   4.23376   9.82546   1.000 59.02000  ? 286 TYR   A CB  1 
ATOM   568  C CG  . TYR   A 1 72  ? 1.90738   3.83352   10.23830  1.000 56.32000  ? 286 TYR   A CG  1 
ATOM   569  C CD1 . TYR   A 1 72  ? 1.06929   4.72925   10.90055  1.000 56.53000  ? 286 TYR   A CD1 1 
ATOM   570  C CD2 . TYR   A 1 72  ? 1.42049   2.56757   9.94789   1.000 55.49000  ? 286 TYR   A CD2 1 
ATOM   571  C CE1 . TYR   A 1 72  ? -0.21069  4.37603   11.26140  1.000 59.53000  ? 286 TYR   A CE1 1 
ATOM   572  C CE2 . TYR   A 1 72  ? 0.13951   2.19836   10.31073  1.000 57.48000  ? 286 TYR   A CE2 1 
ATOM   573  C CZ  . TYR   A 1 72  ? -0.67558  3.10609   10.96699  1.000 60.68000  ? 286 TYR   A CZ  1 
ATOM   574  O OH  . TYR   A 1 72  ? -1.95456  2.73387   11.32883  1.000 59.52000  ? 286 TYR   A OH  1 
ATOM   575  N N   . GLU   A 1 73  ? 3.90113   7.35499   9.25845   1.000 66.98000  ? 287 GLU   A N   1 
ATOM   576  C CA  . GLU   A 1 73  ? 3.62501   8.76489   9.50588   1.000 70.73000  ? 287 GLU   A CA  1 
ATOM   577  C C   . GLU   A 1 73  ? 3.11099   9.45124   8.23708   1.000 67.63000  ? 287 GLU   A C   1 
ATOM   578  O O   . GLU   A 1 73  ? 2.11993   10.19015  8.27728   1.000 65.98000  ? 287 GLU   A O   1 
ATOM   579  C CB  . GLU   A 1 73  ? 4.87793   9.44682   10.06814  1.000 67.39000  ? 287 GLU   A CB  1 
ATOM   580  C CG  . GLU   A 1 73  ? 5.21693   9.00440   11.49801  1.000 69.83000  ? 287 GLU   A CG  1 
ATOM   581  C CD  . GLU   A 1 73  ? 6.67389   9.24139   11.88913  1.000 77.65000  ? 287 GLU   A CD  1 
ATOM   582  O OE1 . GLU   A 1 73  ? 7.46188   9.69873   11.02929  1.000 77.77000  ? 287 GLU   A OE1 1 
ATOM   583  O OE2 . GLU   A 1 73  ? 7.02488   8.97706   13.06806  1.000 78.29000  ? 287 GLU   A OE2 1 
ATOM   584  N N   . LYS   A 1 74  ? 3.75005   9.18265   7.09002   1.000 66.58000  ? 288 LYS   A N   1 
ATOM   585  C CA  . LYS   A 1 74  ? 3.27704   9.74401   5.82618   1.000 62.65000  ? 288 LYS   A CA  1 
ATOM   586  C C   . LYS   A 1 74  ? 1.88609   9.24500   5.49198   1.000 62.92000  ? 288 LYS   A C   1 
ATOM   587  O O   . LYS   A 1 74  ? 1.12006   9.94615   4.82417   1.000 73.81000  ? 288 LYS   A O   1 
ATOM   588  C CB  . LYS   A 1 74  ? 4.24911   9.38743   4.70810   1.000 66.26000  ? 288 LYS   A CB  1 
ATOM   589  C CG  . LYS   A 1 74  ? 3.78213   9.68184   3.29517   1.000 61.91000  ? 288 LYS   A CG  1 
ATOM   590  C CD  . LYS   A 1 74  ? 4.61122   8.83820   2.34494   1.000 62.74000  ? 288 LYS   A CD  1 
ATOM   591  C CE  . LYS   A 1 74  ? 4.32724   9.14563   0.90302   1.000 64.54000  ? 288 LYS   A CE  1 
ATOM   592  N NZ  . LYS   A 1 74  ? 5.03635   8.17596   0.00274   1.000 63.31000  ? 288 LYS   A NZ  1 
ATOM   593  N N   . GLY   A 1 75  ? 1.52717   8.05682   5.97260   1.000 65.32000  ? 289 GLY   A N   1 
ATOM   594  C CA  . GLY   A 1 75  ? 0.23123   7.47680   5.70838   1.000 60.24000  ? 289 GLY   A CA  1 
ATOM   595  C C   . GLY   A 1 75  ? 0.14331   7.07024   4.25525   1.000 68.63000  ? 289 GLY   A C   1 
ATOM   596  O O   . GLY   A 1 75  ? 1.16333   7.01955   3.54426   1.000 70.19000  ? 289 GLY   A O   1 
ATOM   597  N N   . PRO   A 1 76  ? -1.07565  6.78130   3.77112   1.000 65.18000  ? 290 PRO   A N   1 
ATOM   598  C CA  . PRO   A 1 76  ? -2.35067  6.67396   4.51605   1.000 67.34000  ? 290 PRO   A CA  1 
ATOM   599  C C   . PRO   A 1 76  ? -2.43660  5.46767   5.41367   1.000 65.22000  ? 290 PRO   A C   1 
ATOM   600  O O   . PRO   A 1 76  ? -2.11750  4.35582   5.02133   1.000 64.88000  ? 290 PRO   A O   1 
ATOM   601  C CB  . PRO   A 1 76  ? -3.39263  6.64823   3.37401   1.000 56.97000  ? 290 PRO   A CB  1 
ATOM   602  C CG  . PRO   A 1 76  ? -2.67054  5.94363   2.27781   1.000 62.59000  ? 290 PRO   A CG  1 
ATOM   603  C CD  . PRO   A 1 76  ? -1.25558  6.46373   2.34302   1.000 63.47000  ? 290 PRO   A CD  1 
ATOM   604  N N   . PRO   A 1 77  ? -2.92965  5.65326   6.62771   1.000 60.76000  ? 291 PRO   A N   1 
ATOM   605  C CA  . PRO   A 1 77  ? -2.83660  4.58195   7.62738   1.000 62.35000  ? 291 PRO   A CA  1 
ATOM   606  C C   . PRO   A 1 77  ? -3.75449  3.40097   7.34298   1.000 62.95000  ? 291 PRO   A C   1 
ATOM   607  O O   . PRO   A 1 77  ? -3.49742  2.29883   7.85765   1.000 59.49000  ? 291 PRO   A O   1 
ATOM   608  C CB  . PRO   A 1 77  ? -3.19470  5.29152   8.94059   1.000 62.04000  ? 291 PRO   A CB  1 
ATOM   609  C CG  . PRO   A 1 77  ? -3.65480  6.66859   8.59000   1.000 65.42000  ? 291 PRO   A CG  1 
ATOM   610  C CD  . PRO   A 1 77  ? -3.60576  6.85105   7.11006   1.000 62.36000  ? 291 PRO   A CD  1 
ATOM   611  N N   . ASN   A 1 78  ? -4.81748  3.59713   6.55301   1.000 64.04000  ? 292 ASN   A N   1 
ATOM   612  C CA  . ASN   A 1 78  ? -5.63838  2.46519   6.13163   1.000 65.80000  ? 292 ASN   A CA  1 
ATOM   613  C C   . ASN   A 1 78  ? -4.95828  1.62658   5.05139   1.000 66.76000  ? 292 ASN   A C   1 
ATOM   614  O O   . ASN   A 1 78  ? -5.54118  0.62367   4.60806   1.000 62.27000  ? 292 ASN   A O   1 
ATOM   615  C CB  . ASN   A 1 78  ? -6.98740  2.93225   5.58474   1.000 67.27000  ? 292 ASN   A CB  1 
ATOM   616  C CG  . ASN   A 1 78  ? -6.82845  3.95561   4.48206   1.000 65.81000  ? 292 ASN   A CG  1 
ATOM   617  O OD1 . ASN   A 1 78  ? -5.76649  4.57274   4.35129   1.000 71.24000  ? 292 ASN   A OD1 1 
ATOM   618  N ND2 . ASN   A 1 78  ? -7.85644  4.11978   3.66608   1.000 66.23000  ? 292 ASN   A ND2 1 
ATOM   619  N N   . ALA   A 1 79  ? -3.75530  2.02182   4.60855   1.000 58.22000  ? 293 ALA   A N   1 
ATOM   620  C CA  . ALA   A 1 79  ? -3.03420  1.24919   3.60234   1.000 61.88000  ? 293 ALA   A CA  1 
ATOM   621  C C   . ALA   A 1 79  ? -2.17113  0.13707   4.21002   1.000 57.80000  ? 293 ALA   A C   1 
ATOM   622  O O   . ALA   A 1 79  ? -1.85203  -0.83369  3.51973   1.000 59.17000  ? 293 ALA   A O   1 
ATOM   623  C CB  . ALA   A 1 79  ? -2.17425  2.18453   2.74665   1.000 57.00000  ? 293 ALA   A CB  1 
ATOM   624  N N   . PHE   A 1 80  ? -1.81118  0.23270   5.48206   1.000 54.85000  ? 294 PHE   A N   1 
ATOM   625  C CA  . PHE   A 1 80  ? -0.80312  -0.65839  6.05181   1.000 54.93000  ? 294 PHE   A CA  1 
ATOM   626  C C   . PHE   A 1 80  ? -1.43204  -1.91962  6.63040   1.000 54.18000  ? 294 PHE   A C   1 
ATOM   627  O O   . PHE   A 1 80  ? -2.33707  -1.84896  7.46339   1.000 61.71000  ? 294 PHE   A O   1 
ATOM   628  C CB  . PHE   A 1 80  ? -0.01722  0.06233   7.14306   1.000 52.57000  ? 294 PHE   A CB  1 
ATOM   629  C CG  . PHE   A 1 80  ? 0.79970   1.22155   6.65245   1.000 52.86000  ? 294 PHE   A CG  1 
ATOM   630  C CD1 . PHE   A 1 80  ? 0.18663   2.38365   6.18279   1.000 52.54000  ? 294 PHE   A CD1 1 
ATOM   631  C CD2 . PHE   A 1 80  ? 2.19071   1.16665   6.69647   1.000 54.80000  ? 294 PHE   A CD2 1 
ATOM   632  C CE1 . PHE   A 1 80  ? 0.94755   3.46085   5.73915   1.000 58.99000  ? 294 PHE   A CE1 1 
ATOM   633  C CE2 . PHE   A 1 80  ? 2.96263   2.23785   6.26083   1.000 57.29000  ? 294 PHE   A CE2 1 
ATOM   634  C CZ  . PHE   A 1 80  ? 2.34456   3.38795   5.77717   1.000 61.45000  ? 294 PHE   A CZ  1 
ATOM   635  N N   . PHE   A 1 81  ? -0.91994  -3.07345  6.21906   1.000 52.44000  ? 295 PHE   A N   1 
ATOM   636  C CA  . PHE   A 1 81  ? -1.40684  -4.37263  6.66464   1.000 54.32000  ? 295 PHE   A CA  1 
ATOM   637  C C   . PHE   A 1 81  ? -0.22879  -5.24766  7.06740   1.000 52.03000  ? 295 PHE   A C   1 
ATOM   638  O O   . PHE   A 1 81  ? 0.91421   -5.00445  6.67151   1.000 53.58000  ? 295 PHE   A O   1 
ATOM   639  C CB  . PHE   A 1 81  ? -2.17675  -5.08635  5.55239   1.000 55.03000  ? 295 PHE   A CB  1 
ATOM   640  C CG  . PHE   A 1 81  ? -3.47379  -4.45135  5.22655   1.000 62.96000  ? 295 PHE   A CG  1 
ATOM   641  C CD1 . PHE   A 1 81  ? -3.51686  -3.30411  4.44290   1.000 60.81000  ? 295 PHE   A CD1 1 
ATOM   642  C CD2 . PHE   A 1 81  ? -4.66376  -5.00059  5.67834   1.000 62.19000  ? 295 PHE   A CD2 1 
ATOM   643  C CE1 . PHE   A 1 81  ? -4.72990  -2.69312  4.15206   1.000 58.19000  ? 295 PHE   A CE1 1 
ATOM   644  C CE2 . PHE   A 1 81  ? -5.86680  -4.40159  5.37849   1.000 64.01000  ? 295 PHE   A CE2 1 
ATOM   645  C CZ  . PHE   A 1 81  ? -5.90087  -3.24735  4.60685   1.000 59.06000  ? 295 PHE   A CZ  1 
ATOM   646  N N   . LEU   A 1 82  ? -0.51672  -6.30492  7.81506   1.000 49.72000  ? 296 LEU   A N   1 
ATOM   647  C CA  . LEU   A 1 82  ? 0.48735   -7.30794  8.14978   1.000 51.22000  ? 296 LEU   A CA  1 
ATOM   648  C C   . LEU   A 1 82  ? -0.03553  -8.67285  7.73134   1.000 47.93000  ? 296 LEU   A C   1 
ATOM   649  O O   . LEU   A 1 82  ? -1.21051  -8.97501  7.94121   1.000 46.78000  ? 296 LEU   A O   1 
ATOM   650  C CB  . LEU   A 1 82  ? 0.82030   -7.27738  9.65080   1.000 50.97000  ? 296 LEU   A CB  1 
ATOM   651  C CG  . LEU   A 1 82  ? 1.56537   -8.42853  10.33547  1.000 46.97000  ? 296 LEU   A CG  1 
ATOM   652  C CD1 . LEU   A 1 82  ? 3.00339   -8.55327  9.86947   1.000 53.37000  ? 296 LEU   A CD1 1 
ATOM   653  C CD2 . LEU   A 1 82  ? 1.54330   -8.16700  11.80855  1.000 52.47000  ? 296 LEU   A CD2 1 
ATOM   654  N N   . VAL   A 1 83  ? 0.81855   -9.47859  7.10112   1.000 53.10000  ? 297 VAL   A N   1 
ATOM   655  C CA  . VAL   A 1 83  ? 0.45968   -10.82448 6.66069   1.000 51.70000  ? 297 VAL   A CA  1 
ATOM   656  C C   . VAL   A 1 83  ? 1.43574   -11.80560 7.28941   1.000 48.35000  ? 297 VAL   A C   1 
ATOM   657  O O   . VAL   A 1 83  ? 2.65473   -11.63247 7.18150   1.000 48.25000  ? 297 VAL   A O   1 
ATOM   658  C CB  . VAL   A 1 83  ? 0.47073   -10.95400 5.12665   1.000 53.12000  ? 297 VAL   A CB  1 
ATOM   659  C CG1 . VAL   A 1 83  ? 0.33087   -12.43188 4.70918   1.000 52.40000  ? 297 VAL   A CG1 1 
ATOM   660  C CG2 . VAL   A 1 83  ? -0.63431  -10.11090 4.50688   1.000 50.55000  ? 297 VAL   A CG2 1 
ATOM   661  N N   . LYS   A 1 84  ? 0.90680   -12.81585 7.96208   1.000 51.58000  ? 298 LYS   A N   1 
ATOM   662  C CA  . LYS   A 1 84  ? 1.72686   -13.86297 8.55278   1.000 51.39000  ? 298 LYS   A CA  1 
ATOM   663  C C   . LYS   A 1 84  ? 1.60799   -15.09971 7.68439   1.000 52.74000  ? 298 LYS   A C   1 
ATOM   664  O O   . LYS   A 1 84  ? 0.52404   -15.67376 7.56518   1.000 52.06000  ? 298 LYS   A O   1 
ATOM   665  C CB  . LYS   A 1 84  ? 1.29684   -14.17145 9.98367   1.000 58.40000  ? 298 LYS   A CB  1 
ATOM   666  C CG  . LYS   A 1 84  ? 2.07492   -15.32358 10.62634  1.000 60.54000  ? 298 LYS   A CG  1 
ATOM   667  C CD  . LYS   A 1 84  ? 1.66388   -15.48407 12.07728  1.000 62.81000  ? 298 LYS   A CD  1 
ATOM   668  C CE  . LYS   A 1 84  ? 2.32696   -16.67722 12.74492  1.000 66.79000  ? 298 LYS   A CE  1 
ATOM   669  N NZ  . LYS   A 1 84  ? 3.81095   -16.61614 12.87199  1.000 71.21000  ? 298 LYS   A NZ  1 
ATOM   670  N N   . PHE   A 1 85  ? 2.71304   -15.50343 7.07330   1.000 51.43000  ? 299 PHE   A N   1 
ATOM   671  C CA  . PHE   A 1 85  ? 2.70216   -16.64415 6.17195   1.000 54.30000  ? 299 PHE   A CA  1 
ATOM   672  C C   . PHE   A 1 85  ? 3.16324   -17.89734 6.89657   1.000 54.58000  ? 299 PHE   A C   1 
ATOM   673  O O   . PHE   A 1 85  ? 4.11321   -17.85151 7.68661   1.000 50.83000  ? 299 PHE   A O   1 
ATOM   674  C CB  . PHE   A 1 85  ? 3.61618   -16.40570 4.97805   1.000 55.62000  ? 299 PHE   A CB  1 
ATOM   675  C CG  . PHE   A 1 85  ? 2.96016   -15.72840 3.84024   1.000 50.30000  ? 299 PHE   A CG  1 
ATOM   676  C CD1 . PHE   A 1 85  ? 1.77622   -16.21734 3.32405   1.000 48.79000  ? 299 PHE   A CD1 1 
ATOM   677  C CD2 . PHE   A 1 85  ? 3.56009   -14.61417 3.25460   1.000 47.49000  ? 299 PHE   A CD2 1 
ATOM   678  C CE1 . PHE   A 1 85  ? 1.19020   -15.59405 2.25723   1.000 51.41000  ? 299 PHE   A CE1 1 
ATOM   679  C CE2 . PHE   A 1 85  ? 2.98807   -13.98388 2.18078   1.000 46.84000  ? 299 PHE   A CE2 1 
ATOM   680  C CZ  . PHE   A 1 85  ? 1.80413   -14.47382 1.67359   1.000 51.80000  ? 299 PHE   A CZ  1 
ATOM   681  N N   . TRP   A 1 86  ? 2.48334   -19.00931 6.62220   1.000 53.91000  ? 300 TRP   A N   1 
ATOM   682  C CA  . TRP   A 1 86  ? 2.96143   -20.33938 6.97580   1.000 54.41000  ? 300 TRP   A CA  1 
ATOM   683  C C   . TRP   A 1 86  ? 3.44653   -20.99494 5.68661   1.000 59.82000  ? 300 TRP   A C   1 
ATOM   684  O O   . TRP   A 1 86  ? 2.63458   -21.35873 4.82448   1.000 62.94000  ? 300 TRP   A O   1 
ATOM   685  C CB  . TRP   A 1 86  ? 1.87348   -21.17367 7.64951   1.000 57.80000  ? 300 TRP   A CB  1 
ATOM   686  C CG  . TRP   A 1 86  ? 1.57240   -20.74714 9.06163   1.000 64.34000  ? 300 TRP   A CG  1 
ATOM   687  C CD1 . TRP   A 1 86  ? 2.06041   -21.31346 10.21347  1.000 62.85000  ? 300 TRP   A CD1 1 
ATOM   688  C CD2 . TRP   A 1 86  ? 0.69630   -19.69334 9.47993   1.000 62.92000  ? 300 TRP   A CD2 1 
ATOM   689  N NE1 . TRP   A 1 86  ? 1.56333   -20.65684 11.30966  1.000 61.30000  ? 300 TRP   A NE1 1 
ATOM   690  C CE2 . TRP   A 1 86  ? 0.72126   -19.66578 10.88894  1.000 62.64000  ? 300 TRP   A CE2 1 
ATOM   691  C CE3 . TRP   A 1 86  ? -0.09575  -18.76819 8.80220   1.000 61.31000  ? 300 TRP   A CE3 1 
ATOM   692  C CZ2 . TRP   A 1 86  ? -0.02084  -18.75707 11.62620  1.000 61.99000  ? 300 TRP   A CZ2 1 
ATOM   693  C CZ3 . TRP   A 1 86  ? -0.82385  -17.85848 9.54146   1.000 63.01000  ? 300 TRP   A CZ3 1 
ATOM   694  C CH2 . TRP   A 1 86  ? -0.78189  -17.86291 10.93946  1.000 60.18000  ? 300 TRP   A CH2 1 
ATOM   695  N N   . ALA   A 1 87  ? 4.76454   -21.13579 5.55361   1.000 52.84000  ? 301 ALA   A N   1 
ATOM   696  C CA  . ALA   A 1 87  ? 5.37261   -21.52135 4.28851   1.000 53.59000  ? 301 ALA   A CA  1 
ATOM   697  C C   . ALA   A 1 87  ? 5.41674   -23.03029 4.12404   1.000 52.12000  ? 301 ALA   A C   1 
ATOM   698  O O   . ALA   A 1 87  ? 5.80477   -23.75354 5.03583   1.000 57.06000  ? 301 ALA   A O   1 
ATOM   699  C CB  . ALA   A 1 87  ? 6.78557   -20.95120 4.19073   1.000 52.86000  ? 301 ALA   A CB  1 
ATOM   700  N N   . ASP   A 1 88  ? 5.02482   -23.50396 2.94888   1.000 56.91000  ? 302 ASP   A N   1 
ATOM   701  C CA  . ASP   A 1 88  ? 5.11794   -24.92985 2.63644   1.000 63.28000  ? 302 ASP   A CA  1 
ATOM   702  C C   . ASP   A 1 88  ? 6.53398   -25.18658 2.13441   1.000 63.65000  ? 302 ASP   A C   1 
ATOM   703  O O   . ASP   A 1 88  ? 6.88398   -24.80421 1.02054   1.000 58.46000  ? 302 ASP   A O   1 
ATOM   704  C CB  . ASP   A 1 88  ? 4.05600   -25.33162 1.61828   1.000 61.11000  ? 302 ASP   A CB  1 
ATOM   705  C CG  . ASP   A 1 88  ? 4.02813   -26.83154 1.34282   1.000 67.72000  ? 302 ASP   A CG  1 
ATOM   706  O OD1 . ASP   A 1 88  ? 4.96918   -27.55359 1.74762   1.000 62.53000  ? 302 ASP   A OD1 1 
ATOM   707  O OD2 . ASP   A 1 88  ? 3.03719   -27.28742 0.71464   1.000 66.84000  ? 302 ASP   A OD2 1 
ATOM   708  N N   . LEU   A 1 89  ? 7.37100   -25.79478 2.97624   1.000 64.80000  ? 303 LEU   A N   1 
ATOM   709  C CA  . LEU   A 1 89  ? 8.73004   -26.12954 2.58218   1.000 65.56000  ? 303 LEU   A CA  1 
ATOM   710  C C   . LEU   A 1 89  ? 8.88417   -27.56238 2.10374   1.000 74.96000  ? 303 LEU   A C   1 
ATOM   711  O O   . LEU   A 1 89  ? 9.89521   -27.86710 1.45968   1.000 77.30000  ? 303 LEU   A O   1 
ATOM   712  C CB  . LEU   A 1 89  ? 9.70698   -25.87382 3.73629   1.000 62.36000  ? 303 LEU   A CB  1 
ATOM   713  C CG  . LEU   A 1 89  ? 10.11086  -24.40278 3.70776   1.000 57.04000  ? 303 LEU   A CG  1 
ATOM   714  C CD1 . LEU   A 1 89  ? 11.10481  -24.09803 4.76489   1.000 57.26000  ? 303 LEU   A CD1 1 
ATOM   715  C CD2 . LEU   A 1 89  ? 10.68588  -24.09331 2.34288   1.000 62.69000  ? 303 LEU   A CD2 1 
ATOM   716  N N   . ASN   A 1 90  ? 7.88023   -28.38553 2.31945   1.000 75.04000  ? 304 ASN   A N   1 
ATOM   717  C CA  . ASN   A 1 90  ? 7.91935   -29.73838 1.83403   1.000 78.04000  ? 304 ASN   A CA  1 
ATOM   718  C C   . ASN   A 1 90  ? 7.66540   -29.72494 0.35003   1.000 88.54000  ? 304 ASN   A C   1 
ATOM   719  O O   . ASN   A 1 90  ? 6.57944   -30.06488 -0.09611  1.000 88.87000  ? 304 ASN   A O   1 
ATOM   720  C CB  . ASN   A 1 90  ? 6.83240   -30.54167 2.50875   1.000 79.25000  ? 304 ASN   A CB  1 
ATOM   721  C CG  . ASN   A 1 90  ? 6.82734   -30.36014 4.01081   1.000 91.89000  ? 304 ASN   A CG  1 
ATOM   722  O OD1 . ASN   A 1 90  ? 7.79928   -29.88525 4.59298   1.000 98.14000  ? 304 ASN   A OD1 1 
ATOM   723  N ND2 . ASN   A 1 90  ? 5.72935   -30.74243 4.64865   1.000 91.27000  ? 304 ASN   A ND2 1 
ATOM   724  N N   . SER   A 1 91  ? 8.65639   -29.31761 -0.42381  1.000 96.70000  ? 305 SER   A N   1 
ATOM   725  C CA  . SER   A 1 91  ? 8.49443   -29.26118 -1.87080  1.000 92.28000  ? 305 SER   A CA  1 
ATOM   726  C C   . SER   A 1 91  ? 7.99555   -30.53704 -2.45221  1.000 95.23000  ? 305 SER   A C   1 
ATOM   727  O O   . SER   A 1 91  ? 7.09658   -30.52085 -3.28324  1.000 97.59000  ? 305 SER   A O   1 
ATOM   728  C CB  . SER   A 1 91  ? 9.82343   -28.97986 -2.53667  1.000 94.78000  ? 305 SER   A CB  1 
ATOM   729  O OG  . SER   A 1 91  ? 10.69451  -30.08784 -2.38899  1.000 98.49000  ? 305 SER   A OG  1 
ATOM   730  N N   . THR   A 1 92  ? 8.61863   -31.64210 -2.07254  1.000 104.47000 ? 306 THR   A N   1 
ATOM   731  C CA  . THR   A 1 92  ? 8.22375   -32.95698 -2.58196  1.000 109.17000 ? 306 THR   A CA  1 
ATOM   732  C C   . THR   A 1 92  ? 8.32680   -32.99750 -4.08097  1.000 112.01000 ? 306 THR   A C   1 
ATOM   733  O O   . THR   A 1 92  ? 7.49487   -33.61537 -4.73819  1.000 106.24000 ? 306 THR   A O   1 
ATOM   734  C CB  . THR   A 1 92  ? 6.78577   -33.37022 -2.18613  1.000 114.88000 ? 306 THR   A CB  1 
ATOM   735  O OG1 . THR   A 1 92  ? 5.82373   -32.58607 -2.90592  1.000 124.62000 ? 306 THR   A OG1 1 
ATOM   736  C CG2 . THR   A 1 92  ? 6.56971   -33.20770 -0.68809  1.000 114.82000 ? 306 THR   A CG2 1 
ATOM   737  N N   . ILE   A 1 93  ? 9.31776   -32.32825 -4.63173  1.000 111.31000 ? 307 ILE   A N   1 
ATOM   738  C CA  . ILE   A 1 93  ? 9.56981   -32.37779 -6.05474  1.000 111.13000 ? 307 ILE   A CA  1 
ATOM   739  C C   . ILE   A 1 93  ? 11.06582  -32.42667 -6.04971  1.000 106.73000 ? 307 ILE   A C   1 
ATOM   740  O O   . ILE   A 1 93  ? 11.68675  -32.02593 -5.06556  1.000 106.79000 ? 307 ILE   A O   1 
ATOM   741  C CB  . ILE   A 1 93  ? 9.07274   -31.13960 -6.80037  1.000 104.35000 ? 307 ILE   A CB  1 
ATOM   742  C CG1 . ILE   A 1 93  ? 9.83462   -29.89267 -6.35496  1.000 102.12000 ? 307 ILE   A CG1 1 
ATOM   743  C CG2 . ILE   A 1 93  ? 7.58471   -30.93279 -6.57335  1.000 88.63000  ? 307 ILE   A CG2 1 
ATOM   744  C CD1 . ILE   A 1 93  ? 9.35354   -28.63250 -7.03658  1.000 87.53000  ? 307 ILE   A CD1 1 
ATOM   745  N N   . GLN   A 1 94  ? 11.68989  -32.92829 -7.09684  1.000 108.59000 ? 308 GLN   A N   1 
ATOM   746  C CA  . GLN   A 1 94  ? 13.13689  -32.90918 -7.08179  1.000 113.43000 ? 308 GLN   A CA  1 
ATOM   747  C C   . GLN   A 1 94  ? 13.68680  -31.58997 -7.62336  1.000 113.65000 ? 308 GLN   A C   1 
ATOM   748  O O   . GLN   A 1 94  ? 13.79182  -31.40858 -8.83330  1.000 108.48000 ? 308 GLN   A O   1 
ATOM   749  C CB  . GLN   A 1 94  ? 13.69001  -34.09989 -7.86215  1.000 109.44000 ? 308 GLN   A CB  1 
ATOM   750  C CG  . GLN   A 1 94  ? 12.83108  -34.52460 -9.04030  1.000 106.60000 ? 308 GLN   A CG  1 
ATOM   751  C CD  . GLN   A 1 94  ? 13.21521  -35.89240 -9.57172  1.000 103.85000 ? 308 GLN   A CD  1 
ATOM   752  O OE1 . GLN   A 1 94  ? 13.97525  -36.62453 -8.93992  1.000 105.99000 ? 308 GLN   A OE1 1 
ATOM   753  N NE2 . GLN   A 1 94  ? 12.68727  -36.24308 -10.73784 1.000 85.61000  ? 308 GLN   A NE2 1 
ATOM   754  N N   . GLU   A 1 95  ? 13.96669  -30.64622 -6.73806  1.000 113.08000 ? 309 GLU   A N   1 
ATOM   755  C CA  . GLU   A 1 95  ? 14.54461  -29.38104 -7.17265  1.000 112.50000 ? 309 GLU   A CA  1 
ATOM   756  C C   . GLU   A 1 95  ? 15.83165  -29.71372 -7.86871  1.000 107.13000 ? 309 GLU   A C   1 
ATOM   757  O O   . GLU   A 1 95  ? 16.62670  -30.49881 -7.35893  1.000 104.74000 ? 309 GLU   A O   1 
ATOM   758  C CB  . GLU   A 1 95  ? 14.79449  -28.45739 -5.98835  1.000 113.10000 ? 309 GLU   A CB  1 
ATOM   759  C CG  . GLU   A 1 95  ? 13.70747  -28.53480 -4.93041  1.000 110.73000 ? 309 GLU   A CG  1 
ATOM   760  C CD  . GLU   A 1 95  ? 13.84935  -27.45912 -3.87307  1.000 102.78000 ? 309 GLU   A CD  1 
ATOM   761  O OE1 . GLU   A 1 95  ? 14.75728  -26.61501 -4.00178  1.000 96.40000  ? 309 GLU   A OE1 1 
ATOM   762  O OE2 . GLU   A 1 95  ? 13.05032  -27.45448 -2.91510  1.000 105.94000 ? 309 GLU   A OE2 1 
ATOM   763  N N   . GLY   A 1 96  ? 16.06064  -29.12834 -9.03052  1.000 101.74000 ? 310 GLY   A N   1 
ATOM   764  C CA  . GLY   A 1 96  ? 17.22770  -29.50301 -9.78860  1.000 96.23000  ? 310 GLY   A CA  1 
ATOM   765  C C   . GLY   A 1 96  ? 17.84662  -28.33375 -10.46022 1.000 91.82000  ? 310 GLY   A C   1 
ATOM   766  O O   . GLY   A 1 96  ? 17.18955  -27.32373 -10.68293 1.000 92.50000  ? 310 GLY   A O   1 
ATOM   767  N N   . PRO   A 1 97  ? 19.11964  -28.44655 -10.77722 1.000 83.47000  ? 311 PRO   A N   1 
ATOM   768  C CA  . PRO   A 1 97  ? 19.68158  -27.36526 -11.55786 1.000 82.61000  ? 311 PRO   A CA  1 
ATOM   769  C C   . PRO   A 1 97  ? 18.69659  -27.03100 -12.65479 1.000 88.99000  ? 311 PRO   A C   1 
ATOM   770  O O   . PRO   A 1 97  ? 18.24168  -27.92582 -13.35208 1.000 92.03000  ? 311 PRO   A O   1 
ATOM   771  C CB  . PRO   A 1 97  ? 20.92865  -27.99598 -12.14202 1.000 82.09000  ? 311 PRO   A CB  1 
ATOM   772  C CG  . PRO   A 1 97  ? 21.34570  -29.00126 -11.12932 1.000 78.43000  ? 311 PRO   A CG  1 
ATOM   773  C CD  . PRO   A 1 97  ? 20.07572  -29.53754 -10.54253 1.000 83.07000  ? 311 PRO   A CD  1 
ATOM   774  N N   . GLY   A 1 98  ? 18.34749  -25.76698 -12.80041 1.000 88.75000  ? 312 GLY   A N   1 
ATOM   775  C CA  . GLY   A 1 98  ? 17.39149  -25.33874 -13.81230 1.000 79.82000  ? 312 GLY   A CA  1 
ATOM   776  C C   . GLY   A 1 98  ? 15.97345  -25.02299 -13.37925 1.000 77.76000  ? 312 GLY   A C   1 
ATOM   777  O O   . GLY   A 1 98  ? 15.15045  -24.66680 -14.21616 1.000 66.60000  ? 312 GLY   A O   1 
ATOM   778  N N   . ALA   A 1 99  ? 15.67142  -25.12242 -12.09429 1.000 71.69000  ? 313 ALA   A N   1 
ATOM   779  C CA  . ALA   A 1 99  ? 14.36037  -24.70967 -11.60420 1.000 62.17000  ? 313 ALA   A CA  1 
ATOM   780  C C   . ALA   A 1 99  ? 14.15725  -23.19467 -11.66474 1.000 57.63000  ? 313 ALA   A C   1 
ATOM   781  O O   . ALA   A 1 99  ? 15.10818  -22.44864 -11.51947 1.000 66.13000  ? 313 ALA   A O   1 
ATOM   782  C CB  . ALA   A 1 99  ? 14.16336  -25.20413 -10.19636 1.000 55.83000  ? 313 ALA   A CB  1 
ATOM   783  N N   . PHE   A 1 100 ? 12.93622  -22.73270 -11.90363 1.000 49.48000  ? 314 PHE   A N   1 
ATOM   784  C CA  . PHE   A 1 100 ? 12.66510  -21.30173 -11.87519 1.000 49.27000  ? 314 PHE   A CA  1 
ATOM   785  C C   . PHE   A 1 100 ? 12.12303  -20.90519 -10.52809 1.000 49.20000  ? 314 PHE   A C   1 
ATOM   786  O O   . PHE   A 1 100 ? 11.30907  -21.60343 -9.95333  1.000 54.85000  ? 314 PHE   A O   1 
ATOM   787  C CB  . PHE   A 1 100 ? 11.69110  -20.87346 -12.96909 1.000 46.18000  ? 314 PHE   A CB  1 
ATOM   788  C CG  . PHE   A 1 100 ? 11.26398  -19.44153 -12.87366 1.000 49.66000  ? 314 PHE   A CG  1 
ATOM   789  C CD1 . PHE   A 1 100 ? 12.12291  -18.42635 -13.23732 1.000 43.44000  ? 314 PHE   A CD1 1 
ATOM   790  C CD2 . PHE   A 1 100 ? 10.00094  -19.11177 -12.42560 1.000 46.06000  ? 314 PHE   A CD2 1 
ATOM   791  C CE1 . PHE   A 1 100 ? 11.73280  -17.10640 -13.14892 1.000 45.88000  ? 314 PHE   A CE1 1 
ATOM   792  C CE2 . PHE   A 1 100 ? 9.60483   -17.79683 -12.33520 1.000 45.19000  ? 314 PHE   A CE2 1 
ATOM   793  C CZ  . PHE   A 1 100 ? 10.47076  -16.79265 -12.69686 1.000 48.40000  ? 314 PHE   A CZ  1 
ATOM   794  N N   . TYR   A 1 101 ? 12.58392  -19.78331 -10.02272 1.000 46.55000  ? 315 TYR   A N   1 
ATOM   795  C CA  . TYR   A 1 101 ? 12.14884  -19.30375 -8.71659  1.000 45.17000  ? 315 TYR   A CA  1 
ATOM   796  C C   . TYR   A 1 101 ? 11.55074  -17.92274 -8.91018  1.000 47.37000  ? 315 TYR   A C   1 
ATOM   797  O O   . TYR   A 1 101 ? 12.25767  -16.98456 -9.29386  1.000 44.00000  ? 315 TYR   A O   1 
ATOM   798  C CB  . TYR   A 1 101 ? 13.31081  -19.25297 -7.71654  1.000 47.38000  ? 315 TYR   A CB  1 
ATOM   799  C CG  . TYR   A 1 101 ? 13.67989  -20.59313 -7.11294  1.000 51.03000  ? 315 TYR   A CG  1 
ATOM   800  C CD1 . TYR   A 1 101 ? 14.33400  -21.55484 -7.86622  1.000 51.66000  ? 315 TYR   A CD1 1 
ATOM   801  C CD2 . TYR   A 1 101 ? 13.39888  -20.87956 -5.78304  1.000 55.64000  ? 315 TYR   A CD2 1 
ATOM   802  C CE1 . TYR   A 1 101 ? 14.68008  -22.77898 -7.33259  1.000 55.71000  ? 315 TYR   A CE1 1 
ATOM   803  C CE2 . TYR   A 1 101 ? 13.73996  -22.10771 -5.22841  1.000 63.48000  ? 315 TYR   A CE2 1 
ATOM   804  C CZ  . TYR   A 1 101 ? 14.38606  -23.05641 -6.01269  1.000 66.57000  ? 315 TYR   A CZ  1 
ATOM   805  O OH  . TYR   A 1 101 ? 14.73414  -24.28255 -5.48206  1.000 68.37000  ? 315 TYR   A OH  1 
ATOM   806  N N   . GLY   A 1 102 ? 10.25172  -17.79493 -8.63618  1.000 51.66000  ? 316 GLY   A N   1 
ATOM   807  C CA  . GLY   A 1 102 ? 9.57863   -16.55488 -8.96381  1.000 51.44000  ? 316 GLY   A CA  1 
ATOM   808  C C   . GLY   A 1 102 ? 8.47856   -16.15727 -8.00772  1.000 47.09000  ? 316 GLY   A C   1 
ATOM   809  O O   . GLY   A 1 102 ? 8.06260   -16.91557 -7.12997  1.000 43.52000  ? 316 GLY   A O   1 
ATOM   810  N N   . VAL   A 1 103 ? 8.01147   -14.93024 -8.21236  1.000 46.64000  ? 317 VAL   A N   1 
ATOM   811  C CA  . VAL   A 1 103 ? 6.88840   -14.35155 -7.49621  1.000 47.08000  ? 317 VAL   A CA  1 
ATOM   812  C C   . VAL   A 1 103 ? 5.89240   -13.85431 -8.53409  1.000 54.85000  ? 317 VAL   A C   1 
ATOM   813  O O   . VAL   A 1 103 ? 6.28137   -13.20297 -9.51687  1.000 50.71000  ? 317 VAL   A O   1 
ATOM   814  C CB  . VAL   A 1 103 ? 7.32228   -13.21081 -6.55184  1.000 49.64000  ? 317 VAL   A CB  1 
ATOM   815  C CG1 . VAL   A 1 103 ? 6.12220   -12.41107 -6.05463  1.000 51.75000  ? 317 VAL   A CG1 1 
ATOM   816  C CG2 . VAL   A 1 103 ? 8.07529   -13.77112 -5.36299  1.000 47.90000  ? 317 VAL   A CG2 1 
ATOM   817  N N   . SER   A 1 104 ? 4.62542   -14.21247 -8.34324  1.000 49.84000  ? 318 SER   A N   1 
ATOM   818  C CA  . SER   A 1 104 ? 3.52441   -13.74931 -9.16413  1.000 46.46000  ? 318 SER   A CA  1 
ATOM   819  C C   . SER   A 1 104 ? 2.48933   -13.09967 -8.25496  1.000 50.70000  ? 318 SER   A C   1 
ATOM   820  O O   . SER   A 1 104 ? 2.20533   -13.59304 -7.15812  1.000 41.92000  ? 318 SER   A O   1 
ATOM   821  C CB  . SER   A 1 104 ? 2.90152   -14.89112 -9.93850  1.000 44.36000  ? 318 SER   A CB  1 
ATOM   822  O OG  . SER   A 1 104 ? 3.76559   -15.30473 -10.96760 1.000 51.94000  ? 318 SER   A OG  1 
ATOM   823  N N   . SER   A 1 105 ? 1.94625   -11.98358 -8.69963  1.000 45.83000  ? 319 SER   A N   1 
ATOM   824  C CA  . SER   A 1 105 ? 1.02017   -11.28092 -7.85344  1.000 46.96000  ? 319 SER   A CA  1 
ATOM   825  C C   . SER   A 1 105 ? 0.06313   -10.51572 -8.74423  1.000 49.75000  ? 319 SER   A C   1 
ATOM   826  O O   . SER   A 1 105 ? 0.28516   -10.36133 -9.94317  1.000 55.06000  ? 319 SER   A O   1 
ATOM   827  C CB  . SER   A 1 105 ? 1.75706   -10.37817 -6.84813  1.000 48.31000  ? 319 SER   A CB  1 
ATOM   828  O OG  . SER   A 1 105 ? 2.59200   -9.41791  -7.46181  1.000 47.03000  ? 319 SER   A OG  1 
ATOM   829  N N   . GLN   A 1 106 ? -1.02592  -10.06499 -8.14512  1.000 50.64000  ? 320 GLN   A N   1 
ATOM   830  C CA  . GLN   A 1 106 ? -2.04696  -9.32285  -8.85692  1.000 51.24000  ? 320 GLN   A CA  1 
ATOM   831  C C   . GLN   A 1 106 ? -2.62107  -8.29019  -7.91562  1.000 48.72000  ? 320 GLN   A C   1 
ATOM   832  O O   . GLN   A 1 106 ? -2.94108  -8.59958  -6.76373  1.000 50.48000  ? 320 GLN   A O   1 
ATOM   833  C CB  . GLN   A 1 106 ? -3.16087  -10.23478 -9.36924  1.000 56.10000  ? 320 GLN   A CB  1 
ATOM   834  C CG  . GLN   A 1 106 ? -3.96488  -9.64949  -10.50909 1.000 56.27000  ? 320 GLN   A CG  1 
ATOM   835  C CD  . GLN   A 1 106 ? -4.83178  -10.70535 -11.17944 1.000 62.35000  ? 320 GLN   A CD  1 
ATOM   836  O OE1 . GLN   A 1 106 ? -5.87078  -10.39725 -11.77138 1.000 66.30000  ? 320 GLN   A OE1 1 
ATOM   837  N NE2 . GLN   A 1 106 ? -4.41368  -11.96935 -11.07082 1.000 60.74000  ? 320 GLN   A NE2 1 
ATOM   838  N N   . TYR   A 1 107 ? -2.73016  -7.07305  -8.40824  1.000 46.62000  ? 321 TYR   A N   1 
ATOM   839  C CA  . TYR   A 1 107 ? -3.37627  -5.99632  -7.68693  1.000 49.82000  ? 321 TYR   A CA  1 
ATOM   840  C C   . TYR   A 1 107 ? -4.61028  -5.55218  -8.47183  1.000 54.02000  ? 321 TYR   A C   1 
ATOM   841  O O   . TYR   A 1 107 ? -4.85121  -5.98885  -9.60497  1.000 51.20000  ? 321 TYR   A O   1 
ATOM   842  C CB  . TYR   A 1 107 ? -2.39837  -4.83831  -7.47454  1.000 50.41000  ? 321 TYR   A CB  1 
ATOM   843  C CG  . TYR   A 1 107 ? -1.08435  -5.26040  -6.83863  1.000 55.22000  ? 321 TYR   A CG  1 
ATOM   844  C CD1 . TYR   A 1 107 ? -0.09728  -5.88809  -7.59379  1.000 53.16000  ? 321 TYR   A CD1 1 
ATOM   845  C CD2 . TYR   A 1 107 ? -0.81941  -5.01080  -5.49254  1.000 51.58000  ? 321 TYR   A CD2 1 
ATOM   846  C CE1 . TYR   A 1 107 ? 1.10274   -6.27617  -7.02788  1.000 51.06000  ? 321 TYR   A CE1 1 
ATOM   847  C CE2 . TYR   A 1 107 ? 0.38960   -5.39088  -4.91862  1.000 55.34000  ? 321 TYR   A CE2 1 
ATOM   848  C CZ  . TYR   A 1 107 ? 1.35167   -6.02356  -5.69779  1.000 54.81000  ? 321 TYR   A CZ  1 
ATOM   849  O OH  . TYR   A 1 107 ? 2.56369   -6.42263  -5.15188  1.000 53.17000  ? 321 TYR   A OH  1 
ATOM   850  N N   . SER   A 1 108 ? -5.41137  -4.67943  -7.86358  1.000 53.92000  ? 322 SER   A N   1 
ATOM   851  C CA  . SER   A 1 108 ? -6.57639  -4.13131  -8.54445  1.000 53.04000  ? 322 SER   A CA  1 
ATOM   852  C C   . SER   A 1 108 ? -6.80552  -2.69647  -8.10001  1.000 49.99000  ? 322 SER   A C   1 
ATOM   853  O O   . SER   A 1 108 ? -6.49758  -2.32480  -6.96788  1.000 51.15000  ? 322 SER   A O   1 
ATOM   854  C CB  . SER   A 1 108 ? -7.84433  -4.98349  -8.30175  1.000 55.00000  ? 322 SER   A CB  1 
ATOM   855  O OG  . SER   A 1 108 ? -8.27937  -4.92795  -6.94875  1.000 56.79000  ? 322 SER   A OG  1 
ATOM   856  N N   . SER   A 1 109 ? -7.35056  -1.89024  -8.99578  1.000 54.17000  ? 323 SER   A N   1 
ATOM   857  C CA  . SER   A 1 109 ? -7.59968  -0.50036  -8.67435  1.000 54.91000  ? 323 SER   A CA  1 
ATOM   858  C C   . SER   A 1 109 ? -8.84369  -0.01123  -9.40024  1.000 54.56000  ? 323 SER   A C   1 
ATOM   859  O O   . SER   A 1 109 ? -9.26362  -0.57895  -10.40643 1.000 56.27000  ? 323 SER   A O   1 
ATOM   860  C CB  . SER   A 1 109 ? -6.40374  0.36086   -9.04505  1.000 54.74000  ? 323 SER   A CB  1 
ATOM   861  O OG  . SER   A 1 109 ? -6.39785  1.51861   -8.25468  1.000 55.38000  ? 323 SER   A OG  1 
ATOM   862  N N   . ALA   A 1 110 ? -9.44180  1.04955   -8.86693  1.000 50.51000  ? 324 ALA   A N   1 
ATOM   863  C CA  . ALA   A 1 110 ? -10.50083 1.74569   -9.58274  1.000 56.81000  ? 324 ALA   A CA  1 
ATOM   864  C C   . ALA   A 1 110 ? -9.95289  2.85001   -10.47838 1.000 56.91000  ? 324 ALA   A C   1 
ATOM   865  O O   . ALA   A 1 110 ? -10.64090 3.27025   -11.41427 1.000 57.64000  ? 324 ALA   A O   1 
ATOM   866  C CB  . ALA   A 1 110 ? -11.53091 2.32730   -8.60159  1.000 50.52000  ? 324 ALA   A CB  1 
ATOM   867  N N   . ASP   A 1 111 ? -8.73694  3.31803   -10.21120 1.000 57.12000  ? 325 ASP   A N   1 
ATOM   868  C CA  . ASP   A 1 111 ? -8.00098  4.21036   -11.09290 1.000 54.31000  ? 325 ASP   A CA  1 
ATOM   869  C C   . ASP   A 1 111 ? -6.94690  3.43569   -11.87311 1.000 60.25000  ? 325 ASP   A C   1 
ATOM   870  O O   . ASP   A 1 111 ? -6.39983  2.43159   -11.40340 1.000 55.99000  ? 325 ASP   A O   1 
ATOM   871  C CB  . ASP   A 1 111 ? -7.29310  5.30818   -10.30453 1.000 58.79000  ? 325 ASP   A CB  1 
ATOM   872  C CG  . ASP   A 1 111 ? -8.24619  6.29891   -9.70225  1.000 71.09000  ? 325 ASP   A CG  1 
ATOM   873  O OD1 . ASP   A 1 111 ? -9.37117  5.89170   -9.32942  1.000 70.91000  ? 325 ASP   A OD1 1 
ATOM   874  O OD2 . ASP   A 1 111 ? -7.87429  7.49492   -9.63387  1.000 73.38000  ? 325 ASP   A OD2 1 
ATOM   875  N N   . SER   A 1 112 ? -6.67890  3.92009   -13.07995 1.000 67.62000  ? 326 SER   A N   1 
ATOM   876  C CA  . SER   A 1 112 ? -5.48484  3.54642   -13.82503 1.000 66.16000  ? 326 SER   A CA  1 
ATOM   877  C C   . SER   A 1 112 ? -4.28292  4.35736   -13.32674 1.000 66.94000  ? 326 SER   A C   1 
ATOM   878  O O   . SER   A 1 112 ? -4.34603  5.59033   -13.24435 1.000 69.85000  ? 326 SER   A O   1 
ATOM   879  C CB  . SER   A 1 112 ? -5.71682  3.78886   -15.31696 1.000 60.11000  ? 326 SER   A CB  1 
ATOM   880  O OG  . SER   A 1 112 ? -4.51883  4.16916   -15.97280 1.000 66.57000  ? 326 SER   A OG  1 
ATOM   881  N N   . MET   A 1 113 ? -3.19788  3.66834   -12.97092 1.000 62.21000  ? 327 MET   A N   1 
ATOM   882  C CA  . MET   A 1 113 ? -1.94694  4.33133   -12.61667 1.000 64.35000  ? 327 MET   A CA  1 
ATOM   883  C C   . MET   A 1 113 ? -0.77386  3.49958   -13.11389 1.000 60.83000  ? 327 MET   A C   1 
ATOM   884  O O   . MET   A 1 113 ? -0.93676  2.38372   -13.60825 1.000 64.36000  ? 327 MET   A O   1 
ATOM   885  C CB  . MET   A 1 113 ? -1.81301  4.54287   -11.10660 1.000 61.58000  ? 327 MET   A CB  1 
ATOM   886  C CG  . MET   A 1 113 ? -3.13205  4.76054   -10.40857 1.000 63.20000  ? 327 MET   A CG  1 
ATOM   887  S SD  . MET   A 1 113 ? -3.01710  4.73900   -8.62458  1.000 54.66000  ? 327 MET   A SD  1 
ATOM   888  C CE  . MET   A 1 113 ? -4.42103  3.70477   -8.26294  1.000 52.66000  ? 327 MET   A CE  1 
ATOM   889  N N   . THR   A 1 114 ? 0.41609   4.05963   -12.99368 1.000 57.70000  ? 328 THR   A N   1 
ATOM   890  C CA  . THR   A 1 114 ? 1.64115   3.28677   -13.10988 1.000 56.55000  ? 328 THR   A CA  1 
ATOM   891  C C   . THR   A 1 114 ? 2.10313   3.06736   -11.67594 1.000 57.38000  ? 328 THR   A C   1 
ATOM   892  O O   . THR   A 1 114 ? 2.45303   4.02917   -10.98163 1.000 57.60000  ? 328 THR   A O   1 
ATOM   893  C CB  . THR   A 1 114 ? 2.68112   4.02412   -13.95262 1.000 57.59000  ? 328 THR   A CB  1 
ATOM   894  O OG1 . THR   A 1 114 ? 2.14314   4.25048   -15.25257 1.000 61.17000  ? 328 THR   A OG1 1 
ATOM   895  C CG2 . THR   A 1 114 ? 3.92519   3.19227   -14.12184 1.000 57.35000  ? 328 THR   A CG2 1 
ATOM   896  N N   . ILE   A 1 115 ? 2.04021   1.80321   -11.19533 1.000 51.72000  ? 329 ILE   A N   1 
ATOM   897  C CA  . ILE   A 1 115 ? 2.49220   1.49782   -9.83941  1.000 54.00000  ? 329 ILE   A CA  1 
ATOM   898  C C   . ILE   A 1 115 ? 3.97323   1.11694   -9.85249  1.000 59.56000  ? 329 ILE   A C   1 
ATOM   899  O O   . ILE   A 1 115 ? 4.55429   0.72631   -10.88459 1.000 49.66000  ? 329 ILE   A O   1 
ATOM   900  C CB  . ILE   A 1 115 ? 1.62026   0.40954   -9.16478  1.000 49.90000  ? 329 ILE   A CB  1 
ATOM   901  C CG1 . ILE   A 1 115 ? 1.69040   -0.95924  -9.86020  1.000 45.83000  ? 329 ILE   A CG1 1 
ATOM   902  C CG2 . ILE   A 1 115 ? 0.18622   0.87039   -9.04868  1.000 52.07000  ? 329 ILE   A CG2 1 
ATOM   903  C CD1 . ILE   A 1 115 ? 1.25546   -2.11857  -8.92258  1.000 39.98000  ? 329 ILE   A CD1 1 
ATOM   904  N N   . SER   A 1 116 ? 4.60418   1.28763   -8.68441  1.000 56.39000  ? 330 SER   A N   1 
ATOM   905  C CA  . SER   A 1 116 ? 5.98820   0.89167   -8.43649  1.000 50.89000  ? 330 SER   A CA  1 
ATOM   906  C C   . SER   A 1 116 ? 6.03523   0.04728   -7.17376  1.000 48.64000  ? 330 SER   A C   1 
ATOM   907  O O   . SER   A 1 116 ? 5.55116   0.47791   -6.12164  1.000 48.10000  ? 330 SER   A O   1 
ATOM   908  C CB  . SER   A 1 116 ? 6.89810   2.10269   -8.29309  1.000 49.77000  ? 330 SER   A CB  1 
ATOM   909  O OG  . SER   A 1 116 ? 8.21312   1.68670   -7.97118  1.000 64.23000  ? 330 SER   A OG  1 
ATOM   910  N N   . VAL   A 1 117 ? 6.62433   -1.13864  -7.27411  1.000 47.62000  ? 331 VAL   A N   1 
ATOM   911  C CA  . VAL   A 1 117 ? 6.55738   -2.13798  -6.21642  1.000 51.49000  ? 331 VAL   A CA  1 
ATOM   912  C C   . VAL   A 1 117 ? 7.95238   -2.33905  -5.62144  1.000 53.55000  ? 331 VAL   A C   1 
ATOM   913  O O   . VAL   A 1 117 ? 8.83744   -2.93078  -6.25859  1.000 54.31000  ? 331 VAL   A O   1 
ATOM   914  C CB  . VAL   A 1 117 ? 5.96550   -3.45387  -6.73385  1.000 44.71000  ? 331 VAL   A CB  1 
ATOM   915  C CG1 . VAL   A 1 117 ? 6.08456   -4.55418  -5.68419  1.000 41.69000  ? 331 VAL   A CG1 1 
ATOM   916  C CG2 . VAL   A 1 117 ? 4.51449   -3.22487  -7.10982  1.000 41.71000  ? 331 VAL   A CG2 1 
ATOM   917  N N   . SER   A 1 118 ? 8.13930   -1.84742  -4.40228  1.000 46.57000  ? 332 SER   A N   1 
ATOM   918  C CA  . SER   A 1 118 ? 9.34829   -2.07556  -3.63231  1.000 48.07000  ? 332 SER   A CA  1 
ATOM   919  C C   . SER   A 1 118 ? 9.14936   -3.27786  -2.72469  1.000 51.00000  ? 332 SER   A C   1 
ATOM   920  O O   . SER   A 1 118 ? 8.18634   -3.33518  -1.95074  1.000 47.42000  ? 332 SER   A O   1 
ATOM   921  C CB  . SER   A 1 118 ? 9.71217   -0.85279  -2.79392  1.000 47.03000  ? 332 SER   A CB  1 
ATOM   922  O OG  . SER   A 1 118 ? 10.72316  -1.18400  -1.84899  1.000 54.86000  ? 332 SER   A OG  1 
ATOM   923  N N   . THR   A 1 119 ? 10.06544  -4.22675  -2.81696  1.000 52.53000  ? 333 THR   A N   1 
ATOM   924  C CA  . THR   A 1 119 ? 10.09751  -5.37903  -1.92832  1.000 55.75000  ? 333 THR   A CA  1 
ATOM   925  C C   . THR   A 1 119 ? 11.46149  -5.40313  -1.25028  1.000 52.61000  ? 333 THR   A C   1 
ATOM   926  O O   . THR   A 1 119 ? 12.48752  -5.54384  -1.92329  1.000 47.94000  ? 333 THR   A O   1 
ATOM   927  C CB  . THR   A 1 119 ? 9.80663   -6.65881  -2.71372  1.000 55.30000  ? 333 THR   A CB  1 
ATOM   928  O OG1 . THR   A 1 119 ? 8.86164   -6.35556  -3.75266  1.000 61.25000  ? 333 THR   A OG1 1 
ATOM   929  C CG2 . THR   A 1 119 ? 9.21369   -7.71613  -1.83707  1.000 54.03000  ? 333 THR   A CG2 1 
ATOM   930  N N   . LYS   A 1 120 ? 11.47143  -5.21154  0.07378   1.000 46.09000  ? 334 LYS   A N   1 
ATOM   931  C CA  . LYS   A 1 120 ? 12.69840  -5.15669  0.86783   1.000 51.17000  ? 334 LYS   A CA  1 
ATOM   932  C C   . LYS   A 1 120 ? 12.81048  -6.41994  1.71744   1.000 49.60000  ? 334 LYS   A C   1 
ATOM   933  O O   . LYS   A 1 120 ? 12.09546  -6.55831  2.71238   1.000 50.52000  ? 334 LYS   A O   1 
ATOM   934  C CB  . LYS   A 1 120 ? 12.71927  -3.91297  1.76022   1.000 51.05000  ? 334 LYS   A CB  1 
ATOM   935  C CG  . LYS   A 1 120 ? 13.01719  -2.64270  0.99863   1.000 53.38000  ? 334 LYS   A CG  1 
ATOM   936  C CD  . LYS   A 1 120 ? 13.11007  -1.42497  1.88401   1.000 49.59000  ? 334 LYS   A CD  1 
ATOM   937  C CE  . LYS   A 1 120 ? 13.30600  -0.20768  0.98839   1.000 55.48000  ? 334 LYS   A CE  1 
ATOM   938  N NZ  . LYS   A 1 120 ? 13.19087  1.12010   1.66180   1.000 51.40000  ? 334 LYS   A NZ  1 
ATOM   939  N N   . VAL   A 1 121 ? 13.70756  -7.33675  1.32719   1.000 48.18000  ? 335 VAL   A N   1 
ATOM   940  C CA  . VAL   A 1 121 ? 14.06763  -8.45699  2.19485   1.000 47.40000  ? 335 VAL   A CA  1 
ATOM   941  C C   . VAL   A 1 121 ? 14.84354  -7.91930  3.39304   1.000 51.96000  ? 335 VAL   A C   1 
ATOM   942  O O   . VAL   A 1 121 ? 15.63947  -6.97920  3.25836   1.000 49.11000  ? 335 VAL   A O   1 
ATOM   943  C CB  . VAL   A 1 121 ? 14.89373  -9.50569  1.43055   1.000 49.97000  ? 335 VAL   A CB  1 
ATOM   944  C CG1 . VAL   A 1 121 ? 15.05081  -10.78493 2.26315   1.000 51.17000  ? 335 VAL   A CG1 1 
ATOM   945  C CG2 . VAL   A 1 121 ? 14.31980  -9.78531  0.05444   1.000 42.91000  ? 335 VAL   A CG2 1 
ATOM   946  N N   . CYS   A 1 122 ? 14.62356  -8.51269  4.57785   1.000 50.46000  ? 336 CYS   A N   1 
ATOM   947  C CA  . CYS   A 1 122 ? 15.19347  -7.97803  5.81603   1.000 51.24000  ? 336 CYS   A CA  1 
ATOM   948  C C   . CYS   A 1 122 ? 15.61253  -9.06030  6.80171   1.000 52.80000  ? 336 CYS   A C   1 
ATOM   949  O O   . CYS   A 1 122 ? 14.86660  -10.01444 7.05839   1.000 49.08000  ? 336 CYS   A O   1 
ATOM   950  C CB  . CYS   A 1 122 ? 14.22137  -7.02533  6.53030   1.000 52.95000  ? 336 CYS   A CB  1 
ATOM   951  S SG  . CYS   A 1 122 ? 13.79728  -5.55107  5.59174   1.000 59.06000  ? 336 CYS   A SG  1 
ATOM   952  N N   . SER   A 1 123 ? 16.79350  -8.86439  7.38781   1.000 50.95000  ? 337 SER   A N   1 
ATOM   953  C CA  . SER   A 1 123 ? 17.35354  -9.78265  8.36654   1.000 56.15000  ? 337 SER   A CA  1 
ATOM   954  C C   . SER   A 1 123 ? 17.68144  -9.01402  9.63679   1.000 51.25000  ? 337 SER   A C   1 
ATOM   955  O O   . SER   A 1 123 ? 18.32035  -7.95795  9.58714   1.000 52.13000  ? 337 SER   A O   1 
ATOM   956  C CB  . SER   A 1 123 ? 18.59561  -10.47838 7.81436   1.000 51.47000  ? 337 SER   A CB  1 
ATOM   957  O OG  . SER   A 1 123 ? 18.81069  -11.69957 8.49799   1.000 55.28000  ? 337 SER   A OG  1 
ATOM   958  N N   . PHE   A 1 124 ? 17.19644  -9.52541  10.76261  1.000 48.38000  ? 338 PHE   A N   1 
ATOM   959  C CA  . PHE   A 1 124 ? 17.31235  -8.85580  12.05983  1.000 56.22000  ? 338 PHE   A CA  1 
ATOM   960  C C   . PHE   A 1 124 ? 16.98423  -7.36080  11.97528  1.000 59.81000  ? 338 PHE   A C   1 
ATOM   961  O O   . PHE   A 1 124 ? 17.55314  -6.52898  12.69556  1.000 53.53000  ? 338 PHE   A O   1 
ATOM   962  C CB  . PHE   A 1 124 ? 18.69435  -9.11788  12.66579  1.000 54.59000  ? 338 PHE   A CB  1 
ATOM   963  C CG  . PHE   A 1 124 ? 18.83345  -10.51903 13.17736  1.000 51.51000  ? 338 PHE   A CG  1 
ATOM   964  C CD1 . PHE   A 1 124 ? 19.26456  -11.53373 12.33905  1.000 46.32000  ? 338 PHE   A CD1 1 
ATOM   965  C CD2 . PHE   A 1 124 ? 18.44343  -10.83946 14.47024  1.000 52.03000  ? 338 PHE   A CD2 1 
ATOM   966  C CE1 . PHE   A 1 124 ? 19.35165  -12.83986 12.78565  1.000 47.48000  ? 338 PHE   A CE1 1 
ATOM   967  C CE2 . PHE   A 1 124 ? 18.53553  -12.14059 14.92484  1.000 56.57000  ? 338 PHE   A CE2 1 
ATOM   968  C CZ  . PHE   A 1 124 ? 18.99263  -13.14829 14.07154  1.000 55.77000  ? 338 PHE   A CZ  1 
ATOM   969  N N   . GLY   A 1 125 ? 16.00423  -7.02961  11.11535  1.000 60.52000  ? 339 GLY   A N   1 
ATOM   970  C CA  . GLY   A 1 125 ? 15.53413  -5.66859  10.92676  1.000 54.85000  ? 339 GLY   A CA  1 
ATOM   971  C C   . GLY   A 1 125 ? 16.37109  -4.83823  9.97605   1.000 61.85000  ? 339 GLY   A C   1 
ATOM   972  O O   . GLY   A 1 125 ? 16.12800  -3.63021  9.84942   1.000 57.91000  ? 339 GLY   A O   1 
ATOM   973  N N   . LYS   A 1 126 ? 17.35116  -5.44994  9.31189   1.000 56.53000  ? 340 LYS   A N   1 
ATOM   974  C CA  . LYS   A 1 126 ? 18.26613  -4.75459  8.42013   1.000 58.94000  ? 340 LYS   A CA  1 
ATOM   975  C C   . LYS   A 1 126 ? 18.00721  -5.19116  6.98599   1.000 57.80000  ? 340 LYS   A C   1 
ATOM   976  O O   . LYS   A 1 126 ? 17.77632  -6.37610  6.72361   1.000 55.66000  ? 340 LYS   A O   1 
ATOM   977  C CB  . LYS   A 1 126 ? 19.72414  -5.03859  8.80009   1.000 57.80000  ? 340 LYS   A CB  1 
ATOM   978  C CG  . LYS   A 1 126 ? 20.45803  -3.81871  9.36949   1.000 70.19000  ? 340 LYS   A CG  1 
ATOM   979  C CD  . LYS   A 1 126 ? 21.61703  -4.18891  10.32241  1.000 71.96000  ? 340 LYS   A CD  1 
ATOM   980  C CE  . LYS   A 1 126 ? 22.71394  -3.11382  10.32678  1.000 78.93000  ? 340 LYS   A CE  1 
ATOM   981  N NZ  . LYS   A 1 126 ? 24.04296  -3.60188  10.84067  1.000 85.45000  ? 340 LYS   A NZ  1 
ATOM   982  N N   . GLN   A 1 127 ? 18.06316  -4.23087  6.05929   1.000 52.24000  ? 341 GLN   A N   1 
ATOM   983  C CA  . GLN   A 1 127 ? 17.78723  -4.51746  4.65619   1.000 54.79000  ? 341 GLN   A CA  1 
ATOM   984  C C   . GLN   A 1 127 ? 18.92631  -5.31117  4.02998   1.000 58.21000  ? 341 GLN   A C   1 
ATOM   985  O O   . GLN   A 1 127 ? 20.07328  -4.84906  3.98716   1.000 61.48000  ? 341 GLN   A O   1 
ATOM   986  C CB  . GLN   A 1 127 ? 17.55315  -3.22424  3.88159   1.000 52.64000  ? 341 GLN   A CB  1 
ATOM   987  C CG  . GLN   A 1 127 ? 17.64221  -3.38476  2.36354   1.000 53.76000  ? 341 GLN   A CG  1 
ATOM   988  C CD  . GLN   A 1 127 ? 17.32513  -2.09655  1.62793   1.000 55.91000  ? 341 GLN   A CD  1 
ATOM   989  O OE1 . GLN   A 1 127 ? 16.53905  -1.28277  2.11416   1.000 62.01000  ? 341 GLN   A OE1 1 
ATOM   990  N NE2 . GLN   A 1 127 ? 17.92815  -1.90414  0.45801   1.000 51.24000  ? 341 GLN   A NE2 1 
ATOM   991  N N   . VAL   A 1 128 ? 18.60743  -6.50805  3.54860   1.000 54.63000  ? 342 VAL   A N   1 
ATOM   992  C CA  . VAL   A 1 128 ? 19.54951  -7.27672  2.75139   1.000 55.61000  ? 342 VAL   A CA  1 
ATOM   993  C C   . VAL   A 1 128 ? 19.42753  -6.94727  1.26549   1.000 54.90000  ? 342 VAL   A C   1 
ATOM   994  O O   . VAL   A 1 128 ? 20.44355  -6.85697  0.57455   1.000 58.50000  ? 342 VAL   A O   1 
ATOM   995  C CB  . VAL   A 1 128 ? 19.35463  -8.78382  3.00591   1.000 56.18000  ? 342 VAL   A CB  1 
ATOM   996  C CG1 . VAL   A 1 128 ? 20.35671  -9.57149  2.19870   1.000 53.39000  ? 342 VAL   A CG1 1 
ATOM   997  C CG2 . VAL   A 1 128 ? 19.51961  -9.09626  4.45582   1.000 52.64000  ? 342 VAL   A CG2 1 
ATOM   998  N N   . VAL   A 1 129 ? 18.20054  -6.79621  0.74749   1.000 53.47000  ? 343 VAL   A N   1 
ATOM   999  C CA  . VAL   A 1 129 ? 17.93657  -6.64478  -0.68047  1.000 49.20000  ? 343 VAL   A CA  1 
ATOM   1000 C C   . VAL   A 1 129 ? 16.68151  -5.80083  -0.87224  1.000 52.44000  ? 343 VAL   A C   1 
ATOM   1001 O O   . VAL   A 1 129 ? 15.73149  -5.89515  -0.08930  1.000 48.79000  ? 343 VAL   A O   1 
ATOM   1002 C CB  . VAL   A 1 129 ? 17.71970  -8.00458  -1.38990  1.000 56.55000  ? 343 VAL   A CB  1 
ATOM   1003 C CG1 . VAL   A 1 129 ? 17.80173  -7.83110  -2.90784  1.000 55.91000  ? 343 VAL   A CG1 1 
ATOM   1004 C CG2 . VAL   A 1 129 ? 18.67377  -9.08866  -0.90120  1.000 55.54000  ? 343 VAL   A CG2 1 
ATOM   1005 N N   . GLU   A 1 130 ? 16.66148  -5.00549  -1.95500  1.000 54.65000  ? 344 GLU   A N   1 
ATOM   1006 C CA  . GLU   A 1 130 ? 15.45544  -4.33943  -2.44683  1.000 49.33000  ? 344 GLU   A CA  1 
ATOM   1007 C C   . GLU   A 1 130 ? 15.24651  -4.66399  -3.91893  1.000 46.11000  ? 344 GLU   A C   1 
ATOM   1008 O O   . GLU   A 1 130 ? 16.12151  -4.40767  -4.74283  1.000 52.26000  ? 344 GLU   A O   1 
ATOM   1009 C CB  . GLU   A 1 130 ? 15.51331  -2.81648  -2.29135  1.000 47.08000  ? 344 GLU   A CB  1 
ATOM   1010 C CG  . GLU   A 1 130 ? 14.15627  -2.16548  -2.62619  1.000 50.16000  ? 344 GLU   A CG  1 
ATOM   1011 C CD  . GLU   A 1 130 ? 14.13814  -0.64151  -2.53072  1.000 54.16000  ? 344 GLU   A CD  1 
ATOM   1012 O OE1 . GLU   A 1 130 ? 15.20809  -0.00940  -2.61049  1.000 56.59000  ? 344 GLU   A OE1 1 
ATOM   1013 O OE2 . GLU   A 1 130 ? 13.04209  -0.06967  -2.31457  1.000 58.07000  ? 344 GLU   A OE2 1 
ATOM   1014 N N   . LYS   A 1 131 ? 14.08956  -5.20798  -4.25814  1.000 48.97000  ? 345 LYS   A N   1 
ATOM   1015 C CA  . LYS   A 1 131 ? 13.66961  -5.27158  -5.64917  1.000 51.41000  ? 345 LYS   A CA  1 
ATOM   1016 C C   . LYS   A 1 131 ? 12.67453  -4.15558  -5.91086  1.000 51.62000  ? 345 LYS   A C   1 
ATOM   1017 O O   . LYS   A 1 131 ? 11.85248  -3.81692  -5.04978  1.000 50.53000  ? 345 LYS   A O   1 
ATOM   1018 C CB  . LYS   A 1 131 ? 13.02673  -6.60852  -6.01761  1.000 43.43000  ? 345 LYS   A CB  1 
ATOM   1019 C CG  . LYS   A 1 131 ? 12.81379  -6.71407  -7.50365  1.000 49.99000  ? 345 LYS   A CG  1 
ATOM   1020 C CD  . LYS   A 1 131 ? 12.59092  -8.14495  -7.96010  1.000 60.58000  ? 345 LYS   A CD  1 
ATOM   1021 C CE  . LYS   A 1 131 ? 13.55998  -8.50152  -9.08418  1.000 66.65000  ? 345 LYS   A CE  1 
ATOM   1022 N NZ  . LYS   A 1 131 ? 13.05699  -8.12014  -10.43008 1.000 62.53000  ? 345 LYS   A NZ  1 
ATOM   1023 N N   . VAL   A 1 132 ? 12.74252  -3.59120  -7.10968  1.000 51.47000  ? 346 VAL   A N   1 
ATOM   1024 C CA  . VAL   A 1 132 ? 11.83745  -2.53315  -7.52538  1.000 50.41000  ? 346 VAL   A CA  1 
ATOM   1025 C C   . VAL   A 1 132 ? 11.23653  -2.95578  -8.85053  1.000 49.28000  ? 346 VAL   A C   1 
ATOM   1026 O O   . VAL   A 1 132 ? 11.96558  -3.24743  -9.80360  1.000 52.08000  ? 346 VAL   A O   1 
ATOM   1027 C CB  . VAL   A 1 132 ? 12.55534  -1.18205  -7.63393  1.000 45.39000  ? 346 VAL   A CB  1 
ATOM   1028 C CG1 . VAL   A 1 132 ? 11.66329  -0.17391  -8.33165  1.000 50.33000  ? 346 VAL   A CG1 1 
ATOM   1029 C CG2 . VAL   A 1 132 ? 12.96026  -0.70945  -6.24877  1.000 45.59000  ? 346 VAL   A CG2 1 
ATOM   1030 N N   . GLU   A 1 133 ? 9.91853   -3.01587  -8.90759  1.000 50.98000  ? 347 GLU   A N   1 
ATOM   1031 C CA  . GLU   A 1 133 ? 9.22660   -3.44455  -10.11974 1.000 51.86000  ? 347 GLU   A CA  1 
ATOM   1032 C C   . GLU   A 1 133 ? 8.21253   -2.38150  -10.52444 1.000 49.66000  ? 347 GLU   A C   1 
ATOM   1033 O O   . GLU   A 1 133 ? 7.55046   -1.78483  -9.66428  1.000 52.03000  ? 347 GLU   A O   1 
ATOM   1034 C CB  . GLU   A 1 133 ? 8.55371   -4.80368  -9.88519  1.000 44.48000  ? 347 GLU   A CB  1 
ATOM   1035 C CG  . GLU   A 1 133 ? 9.51177   -5.81278  -9.30547  1.000 45.29000  ? 347 GLU   A CG  1 
ATOM   1036 C CD  . GLU   A 1 133 ? 8.83986   -7.07699  -8.81589  1.000 53.60000  ? 347 GLU   A CD  1 
ATOM   1037 O OE1 . GLU   A 1 133 ? 7.86883   -7.00931  -8.01489  1.000 52.44000  ? 347 GLU   A OE1 1 
ATOM   1038 O OE2 . GLU   A 1 133 ? 9.31696   -8.15682  -9.22721  1.000 54.26000  ? 347 GLU   A OE2 1 
ATOM   1039 N N   . THR   A 1 134 ? 8.11155   -2.12011  -11.82537 1.000 46.54000  ? 348 THR   A N   1 
ATOM   1040 C CA  . THR   A 1 134 ? 7.08950   -1.22502  -12.36912 1.000 49.82000  ? 348 THR   A CA  1 
ATOM   1041 C C   . THR   A 1 134 ? 6.01358   -2.05989  -13.05941 1.000 55.26000  ? 348 THR   A C   1 
ATOM   1042 O O   . THR   A 1 134 ? 6.33268   -2.94562  -13.86168 1.000 55.06000  ? 348 THR   A O   1 
ATOM   1043 C CB  . THR   A 1 134 ? 7.68744   -0.21267  -13.35078 1.000 46.56000  ? 348 THR   A CB  1 
ATOM   1044 O OG1 . THR   A 1 134 ? 8.65336   0.61620   -12.68250 1.000 57.23000  ? 348 THR   A OG1 1 
ATOM   1045 C CG2 . THR   A 1 134 ? 6.60839   0.67142   -13.90254 1.000 50.92000  ? 348 THR   A CG2 1 
ATOM   1046 N N   . GLU   A 1 135 ? 4.74055   -1.79409  -12.74237 1.000 49.69000  ? 349 GLU   A N   1 
ATOM   1047 C CA  . GLU   A 1 135 ? 3.64763   -2.55200  -13.32864 1.000 46.44000  ? 349 GLU   A CA  1 
ATOM   1048 C C   . GLU   A 1 135 ? 2.53057   -1.60495  -13.77538 1.000 53.56000  ? 349 GLU   A C   1 
ATOM   1049 O O   . GLU   A 1 135 ? 2.33547   -0.52414  -13.20705 1.000 55.76000  ? 349 GLU   A O   1 
ATOM   1050 C CB  . GLU   A 1 135 ? 3.15669   -3.62735  -12.33599 1.000 46.05000  ? 349 GLU   A CB  1 
ATOM   1051 C CG  . GLU   A 1 135 ? 2.42380   -4.81220  -12.99238 1.000 51.63000  ? 349 GLU   A CG  1 
ATOM   1052 C CD  . GLU   A 1 135 ? 3.00188   -5.18673  -14.36848 1.000 58.03000  ? 349 GLU   A CD  1 
ATOM   1053 O OE1 . GLU   A 1 135 ? 4.15392   -5.68962  -14.41060 1.000 54.42000  ? 349 GLU   A OE1 1 
ATOM   1054 O OE2 . GLU   A 1 135 ? 2.30089   -4.96446  -15.40343 1.000 55.85000  ? 349 GLU   A OE2 1 
ATOM   1055 N N   . TYR   A 1 136 ? 1.81263   -1.99568  -14.82552 1.000 49.68000  ? 350 TYR   A N   1 
ATOM   1056 C CA  . TYR   A 1 136 ? 0.94658   -1.06054  -15.52426 1.000 54.36000  ? 350 TYR   A CA  1 
ATOM   1057 C C   . TYR   A 1 136 ? -0.48838  -1.55565  -15.53346 1.000 54.42000  ? 350 TYR   A C   1 
ATOM   1058 O O   . TYR   A 1 136 ? -0.75128  -2.76567  -15.52384 1.000 50.76000  ? 350 TYR   A O   1 
ATOM   1059 C CB  . TYR   A 1 136 ? 1.40861   -0.82505  -16.96017 1.000 49.60000  ? 350 TYR   A CB  1 
ATOM   1060 C CG  . TYR   A 1 136 ? 2.86458   -0.43788  -17.11601 1.000 57.36000  ? 350 TYR   A CG  1 
ATOM   1061 C CD1 . TYR   A 1 136 ? 3.85966   -1.40980  -17.13128 1.000 57.28000  ? 350 TYR   A CD1 1 
ATOM   1062 C CD2 . TYR   A 1 136 ? 3.24048   0.89820   -17.29158 1.000 56.11000  ? 350 TYR   A CD2 1 
ATOM   1063 C CE1 . TYR   A 1 136 ? 5.18864   -1.06464  -17.28713 1.000 57.69000  ? 350 TYR   A CE1 1 
ATOM   1064 C CE2 . TYR   A 1 136 ? 4.56146   1.25136   -17.46643 1.000 55.67000  ? 350 TYR   A CE2 1 
ATOM   1065 C CZ  . TYR   A 1 136 ? 5.53553   0.26544   -17.46270 1.000 63.34000  ? 350 TYR   A CZ  1 
ATOM   1066 O OH  . TYR   A 1 136 ? 6.86751   0.60260   -17.62256 1.000 64.01000  ? 350 TYR   A OH  1 
ATOM   1067 N N   . ALA   A 1 137 ? -1.41046  -0.59271  -15.57219 1.000 52.48000  ? 351 ALA   A N   1 
ATOM   1068 C CA  . ALA   A 1 137 ? -2.82644  -0.88488  -15.40232 1.000 53.86000  ? 351 ALA   A CA  1 
ATOM   1069 C C   . ALA   A 1 137 ? -3.42935  -1.48753  -16.66653 1.000 54.44000  ? 351 ALA   A C   1 
ATOM   1070 O O   . ALA   A 1 137 ? -3.11135  -1.07816  -17.79339 1.000 53.95000  ? 351 ALA   A O   1 
ATOM   1071 C CB  . ALA   A 1 137 ? -3.58655  0.37994   -15.00395 1.000 54.11000  ? 351 ALA   A CB  1 
ATOM   1072 N N   . ARG   A 1 138 ? -4.29128  -2.47466  -16.46786 1.000 49.78000  ? 352 ARG   A N   1 
ATOM   1073 C CA  . ARG   A 1 138 ? -4.97919  -3.16938  -17.54410 1.000 51.40000  ? 352 ARG   A CA  1 
ATOM   1074 C C   . ARG   A 1 138 ? -6.45519  -3.20261  -17.19416 1.000 56.83000  ? 352 ARG   A C   1 
ATOM   1075 O O   . ARG   A 1 138 ? -6.81720  -3.56399  -16.06928 1.000 60.85000  ? 352 ARG   A O   1 
ATOM   1076 C CB  . ARG   A 1 138 ? -4.44207  -4.59028  -17.72753 1.000 47.75000  ? 352 ARG   A CB  1 
ATOM   1077 C CG  . ARG   A 1 138 ? -2.93206  -4.64715  -17.75750 1.000 56.21000  ? 352 ARG   A CG  1 
ATOM   1078 C CD  . ARG   A 1 138 ? -2.43695  -5.68981  -18.71681 1.000 66.17000  ? 352 ARG   A CD  1 
ATOM   1079 N NE  . ARG   A 1 138 ? -1.24391  -6.37287  -18.23498 1.000 64.13000  ? 352 ARG   A NE  1 
ATOM   1080 C CZ  . ARG   A 1 138 ? -0.09189  -6.37657  -18.88295 1.000 61.37000  ? 352 ARG   A CZ  1 
ATOM   1081 N NH1 . ARG   A 1 138 ? 0.05110   -5.71921  -20.01774 1.000 55.75000  ? 352 ARG   A NH1 1 
ATOM   1082 N NH2 . ARG   A 1 138 ? 0.93715   -7.05565  -18.37413 1.000 71.48000  ? 352 ARG   A NH2 1 
ATOM   1083 N N   . LEU   A 1 139 ? -7.30020  -2.81039  -18.14206 1.000 59.44000  ? 353 LEU   A N   1 
ATOM   1084 C CA  . LEU   A 1 139 ? -8.73720  -2.80158  -17.90610 1.000 58.62000  ? 353 LEU   A CA  1 
ATOM   1085 C C   . LEU   A 1 139 ? -9.32009  -4.21164  -17.85256 1.000 58.96000  ? 353 LEU   A C   1 
ATOM   1086 O O   . LEU   A 1 139 ? -9.17800  -4.99634  -18.79280 1.000 67.68000  ? 353 LEU   A O   1 
ATOM   1087 C CB  . LEU   A 1 139 ? -9.42924  -1.97830  -18.97987 1.000 55.76000  ? 353 LEU   A CB  1 
ATOM   1088 C CG  . LEU   A 1 139 ? -10.90526 -1.78151  -18.67085 1.000 64.66000  ? 353 LEU   A CG  1 
ATOM   1089 C CD1 . LEU   A 1 139 ? -11.17739 -0.41974  -18.02044 1.000 62.56000  ? 353 LEU   A CD1 1 
ATOM   1090 C CD2 . LEU   A 1 139 ? -11.63621 -1.93316  -19.98092 1.000 60.63000  ? 353 LEU   A CD2 1 
ATOM   1091 N N   . GLU   A 1 140 ? -9.98710  -4.52004  -16.74468 1.000 60.46000  ? 354 GLU   A N   1 
ATOM   1092 C CA  . GLU   A 1 140 ? -10.68201 -5.78117  -16.49509 1.000 69.61000  ? 354 GLU   A CA  1 
ATOM   1093 C C   . GLU   A 1 140 ? -12.15304 -5.44337  -16.23003 1.000 72.91000  ? 354 GLU   A C   1 
ATOM   1094 O O   . GLU   A 1 140 ? -12.61812 -4.34631  -16.55570 1.000 74.31000  ? 354 GLU   A O   1 
ATOM   1095 C CB  . GLU   A 1 140 ? -10.00098 -6.53848  -15.34131 1.000 65.73000  ? 354 GLU   A CB  1 
ATOM   1096 C CG  . GLU   A 1 140 ? -10.28687 -8.02554  -15.19478 1.000 64.67000  ? 354 GLU   A CG  1 
ATOM   1097 C CD  . GLU   A 1 140 ? -10.33988 -8.43501  -13.71991 1.000 76.83000  ? 354 GLU   A CD  1 
ATOM   1098 O OE1 . GLU   A 1 140 ? -11.36692 -8.15230  -13.04485 1.000 73.29000  ? 354 GLU   A OE1 1 
ATOM   1099 O OE2 . GLU   A 1 140 ? -9.34685  -9.03208  -13.23006 1.000 76.88000  ? 354 GLU   A OE2 1 
ATOM   1100 N N   . ASN   A 1 141 ? -12.90799 -6.37462  -15.64435 1.000 74.19000  ? 355 ASN   A N   1 
ATOM   1101 C CA  . ASN   A 1 141 ? -14.34601 -6.15879  -15.44932 1.000 72.75000  ? 355 ASN   A CA  1 
ATOM   1102 C C   . ASN   A 1 141 ? -14.58012 -5.18317  -14.29703 1.000 69.45000  ? 355 ASN   A C   1 
ATOM   1103 O O   . ASN   A 1 141 ? -14.50413 -5.55753  -13.12014 1.000 65.34000  ? 355 ASN   A O   1 
ATOM   1104 C CB  . ASN   A 1 141 ? -15.06791 -7.48493  -15.20976 1.000 71.17000  ? 355 ASN   A CB  1 
ATOM   1105 C CG  . ASN   A 1 141 ? -16.57293 -7.32209  -15.08075 1.000 73.53000  ? 355 ASN   A CG  1 
ATOM   1106 O OD1 . ASN   A 1 141 ? -17.23994 -6.82786  -15.98962 1.000 85.94000  ? 355 ASN   A OD1 1 
ATOM   1107 N ND2 . ASN   A 1 141 ? -17.11992 -7.78748  -13.96892 1.000 82.43000  ? 355 ASN   A ND2 1 
ATOM   1108 N N   . GLY   A 1 142 ? -14.86722 -3.92609  -14.63964 1.000 69.03000  ? 356 GLY   A N   1 
ATOM   1109 C CA  . GLY   A 1 142 ? -15.20933 -2.89941  -13.67534 1.000 64.39000  ? 356 GLY   A CA  1 
ATOM   1110 C C   . GLY   A 1 142 ? -14.06339 -2.41859  -12.81715 1.000 65.90000  ? 356 GLY   A C   1 
ATOM   1111 O O   . GLY   A 1 142 ? -14.29748 -1.73692  -11.81194 1.000 72.62000  ? 356 GLY   A O   1 
ATOM   1112 N N   . ARG   A 1 143 ? -12.83136 -2.75338  -13.17722 1.000 63.14000  ? 357 ARG   A N   1 
ATOM   1113 C CA  . ARG   A 1 143 ? -11.67141 -2.36453  -12.38706 1.000 63.13000  ? 357 ARG   A CA  1 
ATOM   1114 C C   . ARG   A 1 143 ? -10.45138 -2.47015  -13.28105 1.000 64.19000  ? 357 ARG   A C   1 
ATOM   1115 O O   . ARG   A 1 143 ? -10.45729 -3.19184  -14.28128 1.000 65.03000  ? 357 ARG   A O   1 
ATOM   1116 C CB  . ARG   A 1 143 ? -11.47838 -3.25790  -11.15333 1.000 57.92000  ? 357 ARG   A CB  1 
ATOM   1117 C CG  . ARG   A 1 143 ? -11.15325 -4.71376  -11.50077 1.000 58.24000  ? 357 ARG   A CG  1 
ATOM   1118 C CD  . ARG   A 1 143 ? -11.16821 -5.63615  -10.27906 1.000 55.14000  ? 357 ARG   A CD  1 
ATOM   1119 N NE  . ARG   A 1 143 ? -10.86909 -7.01300  -10.66448 1.000 63.58000  ? 357 ARG   A NE  1 
ATOM   1120 C CZ  . ARG   A 1 143 ? -10.77103 -8.03726  -9.82280  1.000 63.04000  ? 357 ARG   A CZ  1 
ATOM   1121 N NH1 . ARG   A 1 143 ? -10.98309 -7.88868  -8.52676  1.000 62.83000  ? 357 ARG   A NH1 1 
ATOM   1122 N NH2 . ARG   A 1 143 ? -10.45292 -9.24208  -10.29816 1.000 64.27000  ? 357 ARG   A NH2 1 
ATOM   1123 N N   . PHE   A 1 144 ? -9.40545  -1.74019  -12.90579 1.000 62.12000  ? 358 PHE   A N   1 
ATOM   1124 C CA  . PHE   A 1 144 ? -8.09141  -1.93190  -13.49281 1.000 56.28000  ? 358 PHE   A CA  1 
ATOM   1125 C C   . PHE   A 1 144 ? -7.33636  -2.95310  -12.65511 1.000 57.92000  ? 358 PHE   A C   1 
ATOM   1126 O O   . PHE   A 1 144 ? -7.47439  -2.99049  -11.42912 1.000 55.11000  ? 358 PHE   A O   1 
ATOM   1127 C CB  . PHE   A 1 144 ? -7.34952  -0.60482  -13.55938 1.000 53.98000  ? 358 PHE   A CB  1 
ATOM   1128 C CG  . PHE   A 1 144 ? -7.96256  0.35343   -14.51510 1.000 60.68000  ? 358 PHE   A CG  1 
ATOM   1129 C CD1 . PHE   A 1 144 ? -7.66552  0.28888   -15.87411 1.000 62.00000  ? 358 PHE   A CD1 1 
ATOM   1130 C CD2 . PHE   A 1 144 ? -8.87265  1.29022   -14.07383 1.000 58.75000  ? 358 PHE   A CD2 1 
ATOM   1131 C CE1 . PHE   A 1 144 ? -8.24456  1.16511   -16.76185 1.000 58.85000  ? 358 PHE   A CE1 1 
ATOM   1132 C CE2 . PHE   A 1 144 ? -9.45670  2.16745   -14.95658 1.000 57.62000  ? 358 PHE   A CE2 1 
ATOM   1133 C CZ  . PHE   A 1 144 ? -9.14065  2.10789   -16.30559 1.000 58.69000  ? 358 PHE   A CZ  1 
ATOM   1134 N N   . VAL   A 1 145 ? -6.57927  -3.81683  -13.32035 1.000 52.44000  ? 359 VAL   A N   1 
ATOM   1135 C CA  . VAL   A 1 145 ? -5.84520  -4.88098  -12.65366 1.000 48.75000  ? 359 VAL   A CA  1 
ATOM   1136 C C   . VAL   A 1 145 ? -4.36920  -4.76274  -13.02958 1.000 56.49000  ? 359 VAL   A C   1 
ATOM   1137 O O   . VAL   A 1 145 ? -4.03120  -4.35936  -14.15144 1.000 54.69000  ? 359 VAL   A O   1 
ATOM   1138 C CB  . VAL   A 1 145 ? -6.42608  -6.26091  -13.01211 1.000 48.69000  ? 359 VAL   A CB  1 
ATOM   1139 C CG1 . VAL   A 1 145 ? -5.51100  -7.34397  -12.59742 1.000 54.54000  ? 359 VAL   A CG1 1 
ATOM   1140 C CG2 . VAL   A 1 145 ? -7.73308  -6.45925  -12.28121 1.000 55.45000  ? 359 VAL   A CG2 1 
ATOM   1141 N N   . TYR   A 1 146 ? -3.49220  -5.05697  -12.06964 1.000 52.88000  ? 360 TYR   A N   1 
ATOM   1142 C CA  . TYR   A 1 146 ? -2.05320  -5.06478  -12.29560 1.000 51.19000  ? 360 TYR   A CA  1 
ATOM   1143 C C   . TYR   A 1 146 ? -1.53709  -6.48380  -12.09702 1.000 52.25000  ? 360 TYR   A C   1 
ATOM   1144 O O   . TYR   A 1 146 ? -1.80907  -7.10215  -11.05723 1.000 51.33000  ? 360 TYR   A O   1 
ATOM   1145 C CB  . TYR   A 1 146 ? -1.34930  -4.10202  -11.34828 1.000 46.70000  ? 360 TYR   A CB  1 
ATOM   1146 C CG  . TYR   A 1 146 ? -1.88442  -2.69306  -11.36586 1.000 47.34000  ? 360 TYR   A CG  1 
ATOM   1147 C CD1 . TYR   A 1 146 ? -3.06946  -2.37035  -10.71979 1.000 50.75000  ? 360 TYR   A CD1 1 
ATOM   1148 C CD2 . TYR   A 1 146 ? -1.19448  -1.67780  -12.01252 1.000 47.86000  ? 360 TYR   A CD2 1 
ATOM   1149 C CE1 . TYR   A 1 146 ? -3.55757  -1.06639  -10.71940 1.000 52.50000  ? 360 TYR   A CE1 1 
ATOM   1150 C CE2 . TYR   A 1 146 ? -1.66458  -0.38084  -12.02213 1.000 47.29000  ? 360 TYR   A CE2 1 
ATOM   1151 C CZ  . TYR   A 1 146 ? -2.84663  -0.07413  -11.37207 1.000 54.71000  ? 360 TYR   A CZ  1 
ATOM   1152 O OH  . TYR   A 1 146 ? -3.32873  1.22183   -11.37968 1.000 59.09000  ? 360 TYR   A OH  1 
ATOM   1153 N N   . ARG   A 1 147 ? -0.80902  -7.00443  -13.09116 1.000 50.04000  ? 361 ARG   A N   1 
ATOM   1154 C CA  . ARG   A 1 147 ? -0.36590  -8.40040  -13.09158 1.000 52.83000  ? 361 ARG   A CA  1 
ATOM   1155 C C   . ARG   A 1 147 ? 1.14411   -8.48324  -13.20556 1.000 50.81000  ? 361 ARG   A C   1 
ATOM   1156 O O   . ARG   A 1 147 ? 1.71610   -8.03289  -14.19941 1.000 59.10000  ? 361 ARG   A O   1 
ATOM   1157 C CB  . ARG   A 1 147 ? -0.99880  -9.20410  -14.22885 1.000 57.24000  ? 361 ARG   A CB  1 
ATOM   1158 C CG  . ARG   A 1 147 ? -2.50281  -9.04818  -14.34485 1.000 55.89000  ? 361 ARG   A CG  1 
ATOM   1159 C CD  . ARG   A 1 147 ? -3.08570  -10.11896 -15.21220 1.000 51.10000  ? 361 ARG   A CD  1 
ATOM   1160 N NE  . ARG   A 1 147 ? -4.53371  -10.05810 -15.13123 1.000 56.41000  ? 361 ARG   A NE  1 
ATOM   1161 C CZ  . ARG   A 1 147 ? -5.33270  -9.69486  -16.12314 1.000 63.80000  ? 361 ARG   A CZ  1 
ATOM   1162 N NH1 . ARG   A 1 147 ? -4.86169  -9.44744  -17.33705 1.000 58.97000  ? 361 ARG   A NH1 1 
ATOM   1163 N NH2 . ARG   A 1 147 ? -6.63872  -9.57703  -15.88915 1.000 69.81000  ? 361 ARG   A NH2 1 
ATOM   1164 N N   . ILE   A 1 148 ? 1.78112   -9.06650  -12.19772 1.000 54.90000  ? 362 ILE   A N   1 
ATOM   1165 C CA  . ILE   A 1 148 ? 3.19615   -9.41338  -12.22679 1.000 51.28000  ? 362 ILE   A CA  1 
ATOM   1166 C C   . ILE   A 1 148 ? 3.25428   -10.93133 -12.38126 1.000 52.11000  ? 362 ILE   A C   1 
ATOM   1167 O O   . ILE   A 1 148 ? 2.83831   -11.66764 -11.47750 1.000 51.66000  ? 362 ILE   A O   1 
ATOM   1168 C CB  . ILE   A 1 148 ? 3.93007   -8.92471  -10.96661 1.000 47.72000  ? 362 ILE   A CB  1 
ATOM   1169 C CG1 . ILE   A 1 148 ? 4.00795   -7.39671  -10.94314 1.000 50.37000  ? 362 ILE   A CG1 1 
ATOM   1170 C CG2 . ILE   A 1 148 ? 5.33611   -9.45262  -10.90373 1.000 47.31000  ? 362 ILE   A CG2 1 
ATOM   1171 C CD1 . ILE   A 1 148 ? 4.00086   -6.78215  -9.53294  1.000 41.71000  ? 362 ILE   A CD1 1 
ATOM   1172 N N   . HIS   A 1 149 ? 3.69535   -11.39192 -13.56139 1.000 52.74000  ? 363 HIS   A N   1 
ATOM   1173 C CA  . HIS   A 1 149 ? 3.84048   -12.80881 -13.90183 1.000 53.52000  ? 363 HIS   A CA  1 
ATOM   1174 C C   . HIS   A 1 149 ? 5.30051   -13.21274 -13.75391 1.000 55.09000  ? 363 HIS   A C   1 
ATOM   1175 O O   . HIS   A 1 149 ? 6.18548   -12.60847 -14.37969 1.000 50.94000  ? 363 HIS   A O   1 
ATOM   1176 C CB  . HIS   A 1 149 ? 3.40555   -13.12539 -15.34094 1.000 54.71000  ? 363 HIS   A CB  1 
ATOM   1177 C CG  . HIS   A 1 149 ? 2.05252   -12.60339 -15.72082 1.000 69.37000  ? 363 HIS   A CG  1 
ATOM   1178 N ND1 . HIS   A 1 149 ? 1.87947   -11.60011 -16.65551 1.000 74.43000  ? 363 HIS   A ND1 1 
ATOM   1179 C CD2 . HIS   A 1 149 ? 0.80754   -12.98360 -15.34197 1.000 66.24000  ? 363 HIS   A CD2 1 
ATOM   1180 C CE1 . HIS   A 1 149 ? 0.58645   -11.36117 -16.80748 1.000 66.91000  ? 363 HIS   A CE1 1 
ATOM   1181 N NE2 . HIS   A 1 149 ? -0.08451  -12.18646 -16.01975 1.000 67.45000  ? 363 HIS   A NE2 1 
ATOM   1182 N N   . ARG   A 1 150 ? 5.54356   -14.24497 -12.94922 1.000 49.40000  ? 364 ARG   A N   1 
ATOM   1183 C CA  . ARG   A 1 150 ? 6.83962   -14.91988 -12.89539 1.000 51.43000  ? 364 ARG   A CA  1 
ATOM   1184 C C   . ARG   A 1 150 ? 8.02454   -13.94581 -12.80205 1.000 46.94000  ? 364 ARG   A C   1 
ATOM   1185 O O   . ARG   A 1 150 ? 9.05857   -14.12853 -13.44307 1.000 51.94000  ? 364 ARG   A O   1 
ATOM   1186 C CB  . ARG   A 1 150 ? 6.96973   -15.85949 -14.09468 1.000 47.88000  ? 364 ARG   A CB  1 
ATOM   1187 C CG  . ARG   A 1 150 ? 5.78681   -16.78755 -14.21500 1.000 51.02000  ? 364 ARG   A CG  1 
ATOM   1188 C CD  . ARG   A 1 150 ? 6.14894   -18.12333 -14.83841 1.000 51.49000  ? 364 ARG   A CD  1 
ATOM   1189 N NE  . ARG   A 1 150 ? 7.39796   -18.06199 -15.58935 1.000 56.35000  ? 364 ARG   A NE  1 
ATOM   1190 C CZ  . ARG   A 1 150 ? 8.20704   -19.09687 -15.78165 1.000 54.89000  ? 364 ARG   A CZ  1 
ATOM   1191 N NH1 . ARG   A 1 150 ? 7.91013   -20.30104 -15.31503 1.000 53.51000  ? 364 ARG   A NH1 1 
ATOM   1192 N NH2 . ARG   A 1 150 ? 9.33205   -18.92556 -16.47556 1.000 52.13000  ? 364 ARG   A NH2 1 
ATOM   1193 N N   . SER   A 1 151 ? 7.88343   -12.90507 -11.99573 1.000 45.73000  ? 365 SER   A N   1 
ATOM   1194 C CA  . SER   A 1 151 ? 9.02735   -12.05409 -11.65743 1.000 45.44000  ? 365 SER   A CA  1 
ATOM   1195 C C   . SER   A 1 151 ? 10.12139  -12.88121 -10.98465 1.000 43.48000  ? 365 SER   A C   1 
ATOM   1196 O O   . SER   A 1 151 ? 9.86341   -13.48855 -9.93885  1.000 45.96000  ? 365 SER   A O   1 
ATOM   1197 C CB  . SER   A 1 151 ? 8.58023   -10.92841 -10.73009 1.000 42.61000  ? 365 SER   A CB  1 
ATOM   1198 O OG  . SER   A 1 151 ? 9.68216   -10.25449 -10.18585 1.000 41.04000  ? 365 SER   A OG  1 
ATOM   1199 N N   . PRO   A 1 152 ? 11.33541  -12.93194 -11.52863 1.000 49.09000  ? 366 PRO   A N   1 
ATOM   1200 C CA  . PRO   A 1 152 ? 12.34047  -13.87102 -11.00989 1.000 44.32000  ? 366 PRO   A CA  1 
ATOM   1201 C C   . PRO   A 1 152 ? 12.78440  -13.52442 -9.60477  1.000 41.14000  ? 366 PRO   A C   1 
ATOM   1202 O O   . PRO   A 1 152 ? 12.99630  -12.35951 -9.27040  1.000 42.58000  ? 366 PRO   A O   1 
ATOM   1203 C CB  . PRO   A 1 152 ? 13.50949  -13.72162 -11.99181 1.000 43.68000  ? 366 PRO   A CB  1 
ATOM   1204 C CG  . PRO   A 1 152 ? 12.90049  -13.17529 -13.21466 1.000 47.07000  ? 366 PRO   A CG  1 
ATOM   1205 C CD  . PRO   A 1 152 ? 11.82640  -12.23753 -12.72940 1.000 51.94000  ? 366 PRO   A CD  1 
ATOM   1206 N N   . MET   A 1 153 ? 12.93146  -14.56267 -8.78809  1.000 43.17000  ? 367 MET   A N   1 
ATOM   1207 C CA  . MET   A 1 153 ? 13.45441  -14.40604 -7.43702  1.000 49.73000  ? 367 MET   A CA  1 
ATOM   1208 C C   . MET   A 1 153 ? 14.92538  -14.01792 -7.46786  1.000 53.95000  ? 367 MET   A C   1 
ATOM   1209 O O   . MET   A 1 153 ? 15.69544  -14.45958 -8.33097  1.000 48.77000  ? 367 MET   A O   1 
ATOM   1210 C CB  . MET   A 1 153 ? 13.28349  -15.70930 -6.65143  1.000 51.78000  ? 367 MET   A CB  1 
ATOM   1211 C CG  . MET   A 1 153 ? 12.05047  -15.80767 -5.78450  1.000 43.15000  ? 367 MET   A CG  1 
ATOM   1212 S SD  . MET   A 1 153 ? 12.33354  -17.15401 -4.62991  1.000 57.35000  ? 367 MET   A SD  1 
ATOM   1213 C CE  . MET   A 1 153 ? 10.67859  -17.83619 -4.47618  1.000 42.61000  ? 367 MET   A CE  1 
ATOM   1214 N N   . CYS   A 1 154 ? 15.31928  -13.17518 -6.52158  1.000 56.41000  ? 368 CYS   A N   1 
ATOM   1215 C CA  . CYS   A 1 154 ? 16.73325  -12.85607 -6.50344  1.000 55.21000  ? 368 CYS   A CA  1 
ATOM   1216 C C   . CYS   A 1 154 ? 17.51432  -13.97521 -5.83576  1.000 56.10000  ? 368 CYS   A C   1 
ATOM   1217 O O   . CYS   A 1 154 ? 16.97337  -14.82948 -5.12404  1.000 53.05000  ? 368 CYS   A O   1 
ATOM   1218 C CB  . CYS   A 1 154 ? 17.01712  -11.56428 -5.75903  1.000 56.44000  ? 368 CYS   A CB  1 
ATOM   1219 S SG  . CYS   A 1 154 ? 16.27607  -11.56484 -4.13805  1.000 56.25000  ? 368 CYS   A SG  1 
ATOM   1220 N N   . GLU   A 1 155 ? 18.82532  -13.90305 -6.02770  1.000 61.61000  ? 369 GLU   A N   1 
ATOM   1221 C CA  . GLU   A 1 155 ? 19.71940  -14.99609 -5.66901  1.000 65.66000  ? 369 GLU   A CA  1 
ATOM   1222 C C   . GLU   A 1 155 ? 19.76937  -15.21355 -4.16008  1.000 63.33000  ? 369 GLU   A C   1 
ATOM   1223 O O   . GLU   A 1 155 ? 19.82145  -16.35970 -3.69243  1.000 62.33000  ? 369 GLU   A O   1 
ATOM   1224 C CB  . GLU   A 1 155 ? 21.11139  -14.70580 -6.21888  1.000 65.58000  ? 369 GLU   A CB  1 
ATOM   1225 C CG  . GLU   A 1 155 ? 21.20141  -14.32433 -7.71576  1.000 80.49000  ? 369 GLU   A CG  1 
ATOM   1226 C CD  . GLU   A 1 155 ? 20.24733  -13.18826 -8.19143  1.000 81.39000  ? 369 GLU   A CD  1 
ATOM   1227 O OE1 . GLU   A 1 155 ? 20.04523  -12.19851 -7.42913  1.000 71.40000  ? 369 GLU   A OE1 1 
ATOM   1228 O OE2 . GLU   A 1 155 ? 19.68238  -13.31096 -9.31849  1.000 79.20000  ? 369 GLU   A OE2 1 
ATOM   1229 N N   . TYR   A 1 156 ? 19.75326  -14.12980 -3.38274  1.000 55.06000  ? 370 TYR   A N   1 
ATOM   1230 C CA  . TYR   A 1 156 ? 19.71822  -14.24325 -1.92978  1.000 48.82000  ? 370 TYR   A CA  1 
ATOM   1231 C C   . TYR   A 1 156 ? 18.58328  -15.14449 -1.47209  1.000 50.99000  ? 370 TYR   A C   1 
ATOM   1232 O O   . TYR   A 1 156 ? 18.78333  -16.04972 -0.65637  1.000 53.37000  ? 370 TYR   A O   1 
ATOM   1233 C CB  . TYR   A 1 156 ? 19.60009  -12.84945 -1.31135  1.000 49.80000  ? 370 TYR   A CB  1 
ATOM   1234 C CG  . TYR   A 1 156 ? 19.58604  -12.84892 0.19765   1.000 56.94000  ? 370 TYR   A CG  1 
ATOM   1235 C CD1 . TYR   A 1 156 ? 20.77002  -12.85205 0.92269   1.000 53.64000  ? 370 TYR   A CD1 1 
ATOM   1236 C CD2 . TYR   A 1 156 ? 18.38902  -12.83824 0.90462   1.000 57.29000  ? 370 TYR   A CD2 1 
ATOM   1237 C CE1 . TYR   A 1 156 ? 20.76898  -12.86149 2.30769   1.000 54.55000  ? 370 TYR   A CE1 1 
ATOM   1238 C CE2 . TYR   A 1 156 ? 18.37698  -12.85168 2.30362   1.000 58.33000  ? 370 TYR   A CE2 1 
ATOM   1239 C CZ  . TYR   A 1 156 ? 19.57496  -12.85580 2.99265   1.000 57.40000  ? 370 TYR   A CZ  1 
ATOM   1240 O OH  . TYR   A 1 156 ? 19.59091  -12.86122 4.36265   1.000 52.18000  ? 370 TYR   A OH  1 
ATOM   1241 N N   . MET   A 1 157 ? 17.38328  -14.93442 -2.01006  1.000 56.02000  ? 371 MET   A N   1 
ATOM   1242 C CA  . MET   A 1 157 ? 16.23233  -15.70665 -1.55234  1.000 51.54000  ? 371 MET   A CA  1 
ATOM   1243 C C   . MET   A 1 157 ? 16.29746  -17.15951 -1.99479  1.000 51.98000  ? 371 MET   A C   1 
ATOM   1244 O O   . MET   A 1 157 ? 15.84551  -18.04877 -1.26908  1.000 48.19000  ? 371 MET   A O   1 
ATOM   1245 C CB  . MET   A 1 157 ? 14.94429  -15.06360 -2.05218  1.000 54.68000  ? 371 MET   A CB  1 
ATOM   1246 C CG  . MET   A 1 157 ? 14.72616  -13.75383 -1.37878  1.000 56.31000  ? 371 MET   A CG  1 
ATOM   1247 S SD  . MET   A 1 157 ? 14.25313  -14.03939 0.32012   1.000 48.60000  ? 371 MET   A SD  1 
ATOM   1248 C CE  . MET   A 1 157 ? 13.46327  -15.66945 0.30358   1.000 45.22000  ? 371 MET   A CE  1 
ATOM   1249 N N   . ILE   A 1 158 ? 16.79952  -17.41809 -3.20186  1.000 48.62000  ? 372 ILE   A N   1 
ATOM   1250 C CA  . ILE   A 1 158 ? 16.97264  -18.80295 -3.61528  1.000 51.21000  ? 372 ILE   A CA  1 
ATOM   1251 C C   . ILE   A 1 158 ? 17.90967  -19.51917 -2.65148  1.000 51.56000  ? 372 ILE   A C   1 
ATOM   1252 O O   . ILE   A 1 158 ? 17.60974  -20.62634 -2.18983  1.000 50.85000  ? 372 ILE   A O   1 
ATOM   1253 C CB  . ILE   A 1 158 ? 17.44369  -18.87645 -5.08629  1.000 58.82000  ? 372 ILE   A CB  1 
ATOM   1254 C CG1 . ILE   A 1 158 ? 16.58964  -17.94325 -5.94803  1.000 56.22000  ? 372 ILE   A CG1 1 
ATOM   1255 C CG2 . ILE   A 1 158 ? 17.37083  -20.30229 -5.63774  1.000 53.92000  ? 372 ILE   A CG2 1 
ATOM   1256 C CD1 . ILE   A 1 158 ? 17.00168  -17.86577 -7.38599  1.000 48.05000  ? 372 ILE   A CD1 1 
ATOM   1257 N N   . ASN   A 1 159 ? 19.03161  -18.87720 -2.28824  1.000 51.21000  ? 373 ASN   A N   1 
ATOM   1258 C CA  . ASN   A 1 159 ? 19.95862  -19.47642 -1.32240  1.000 56.90000  ? 373 ASN   A CA  1 
ATOM   1259 C C   . ASN   A 1 159 ? 19.29260  -19.68089 0.02152   1.000 50.23000  ? 373 ASN   A C   1 
ATOM   1260 O O   . ASN   A 1 159 ? 19.47366  -20.72508 0.66120   1.000 52.48000  ? 373 ASN   A O   1 
ATOM   1261 C CB  . ASN   A 1 159 ? 21.19455  -18.60339 -1.10909  1.000 55.72000  ? 373 ASN   A CB  1 
ATOM   1262 C CG  . ASN   A 1 159 ? 22.01657  -18.47394 -2.32602  1.000 66.03000  ? 373 ASN   A CG  1 
ATOM   1263 O OD1 . ASN   A 1 159 ? 21.85467  -19.23366 -3.27326  1.000 74.80000  ? 373 ASN   A OD1 1 
ATOM   1264 N ND2 . ASN   A 1 159 ? 22.93750  -17.51987 -2.31770  1.000 75.29000  ? 373 ASN   A ND2 1 
ATOM   1265 N N   . PHE   A 1 160 ? 18.56550  -18.66310 0.47881   1.000 42.02000  ? 374 PHE   A N   1 
ATOM   1266 C CA  . PHE   A 1 160 ? 17.88247  -18.73155 1.76077   1.000 44.11000  ? 374 PHE   A CA  1 
ATOM   1267 C C   . PHE   A 1 160 ? 16.88256  -19.88964 1.80238   1.000 44.20000  ? 374 PHE   A C   1 
ATOM   1268 O O   . PHE   A 1 160 ? 16.85659  -20.65894 2.76314   1.000 48.29000  ? 374 PHE   A O   1 
ATOM   1269 C CB  . PHE   A 1 160 ? 17.21635  -17.38868 2.02217   1.000 43.66000  ? 374 PHE   A CB  1 
ATOM   1270 C CG  . PHE   A 1 160 ? 16.38731  -17.34913 3.24815   1.000 47.72000  ? 374 PHE   A CG  1 
ATOM   1271 C CD1 . PHE   A 1 160 ? 16.94024  -16.98747 4.46528   1.000 43.59000  ? 374 PHE   A CD1 1 
ATOM   1272 C CD2 . PHE   A 1 160 ? 15.04334  -17.69222 3.19400   1.000 44.83000  ? 374 PHE   A CD2 1 
ATOM   1273 C CE1 . PHE   A 1 160 ? 16.16520  -16.95388 5.58827   1.000 41.69000  ? 374 PHE   A CE1 1 
ATOM   1274 C CE2 . PHE   A 1 160 ? 14.27130  -17.66064 4.32199   1.000 46.00000  ? 374 PHE   A CE2 1 
ATOM   1275 C CZ  . PHE   A 1 160 ? 14.83223  -17.28896 5.51812   1.000 46.97000  ? 374 PHE   A CZ  1 
ATOM   1276 N N   . ILE   A 1 161 ? 16.09661  -20.06738 0.74230   1.000 43.45000  ? 375 ILE   A N   1 
ATOM   1277 C CA  . ILE   A 1 161 ? 15.11570  -21.14645 0.71893   1.000 48.25000  ? 375 ILE   A CA  1 
ATOM   1278 C C   . ILE   A 1 161 ? 15.80380  -22.50642 0.79753   1.000 48.00000  ? 375 ILE   A C   1 
ATOM   1279 O O   . ILE   A 1 161 ? 15.48184  -23.32571 1.66326   1.000 51.28000  ? 375 ILE   A O   1 
ATOM   1280 C CB  . ILE   A 1 161 ? 14.21872  -21.01613 -0.52706  1.000 49.93000  ? 375 ILE   A CB  1 
ATOM   1281 C CG1 . ILE   A 1 161 ? 13.44762  -19.69621 -0.47167  1.000 45.10000  ? 375 ILE   A CG1 1 
ATOM   1282 C CG2 . ILE   A 1 161 ? 13.26682  -22.20817 -0.66746  1.000 43.03000  ? 375 ILE   A CG2 1 
ATOM   1283 C CD1 . ILE   A 1 161 ? 12.78663  -19.33286 -1.78258  1.000 48.08000  ? 375 ILE   A CD1 1 
ATOM   1284 N N   . HIS   A 1 162 ? 16.77685  -22.75806 -0.08652  1.000 55.22000  ? 376 HIS   A N   1 
ATOM   1285 C CA  . HIS   A 1 162 ? 17.48395  -24.04101 -0.06790  1.000 60.01000  ? 376 HIS   A CA  1 
ATOM   1286 C C   . HIS   A 1 162 ? 18.11793  -24.29838 1.28504   1.000 57.80000  ? 376 HIS   A C   1 
ATOM   1287 O O   . HIS   A 1 162 ? 17.89600  -25.34859 1.89871   1.000 59.43000  ? 376 HIS   A O   1 
ATOM   1288 C CB  . HIS   A 1 162 ? 18.56199  -24.09259 -1.14888  1.000 58.18000  ? 376 HIS   A CB  1 
ATOM   1289 C CG  . HIS   A 1 162 ? 18.01304  -24.15920 -2.52992  1.000 61.09000  ? 376 HIS   A CG  1 
ATOM   1290 N ND1 . HIS   A 1 162 ? 18.54501  -23.43583 -3.57667  1.000 71.42000  ? 376 HIS   A ND1 1 
ATOM   1291 C CD2 . HIS   A 1 162 ? 16.94411  -24.82013 -3.03016  1.000 62.05000  ? 376 HIS   A CD2 1 
ATOM   1292 C CE1 . HIS   A 1 162 ? 17.85207  -23.68155 -4.67377  1.000 69.84000  ? 376 HIS   A CE1 1 
ATOM   1293 N NE2 . HIS   A 1 162 ? 16.87213  -24.51572 -4.36706  1.000 75.72000  ? 376 HIS   A NE2 1 
ATOM   1294 N N   . LYS   A 1 163 ? 18.92284  -23.34947 1.76236   1.000 51.41000  ? 377 LYS   A N   1 
ATOM   1295 C CA  . LYS   A 1 163 ? 19.57982  -23.54081 3.04933   1.000 56.52000  ? 377 LYS   A CA  1 
ATOM   1296 C C   . LYS   A 1 163 ? 18.55480  -23.76724 4.15122   1.000 54.24000  ? 377 LYS   A C   1 
ATOM   1297 O O   . LYS   A 1 163 ? 18.69285  -24.69348 4.95494   1.000 55.38000  ? 377 LYS   A O   1 
ATOM   1298 C CB  . LYS   A 1 163 ? 20.48271  -22.35284 3.36872   1.000 53.35000  ? 377 LYS   A CB  1 
ATOM   1299 C CG  . LYS   A 1 163 ? 21.73973  -22.29247 2.51978   1.000 49.86000  ? 377 LYS   A CG  1 
ATOM   1300 C CD  . LYS   A 1 163 ? 22.56762  -21.08053 2.92118   1.000 64.36000  ? 377 LYS   A CD  1 
ATOM   1301 C CE  . LYS   A 1 163 ? 23.87064  -20.98119 2.15026   1.000 75.03000  ? 377 LYS   A CE  1 
ATOM   1302 N NZ  . LYS   A 1 163 ? 24.64753  -19.80527 2.63165   1.000 81.57000  ? 377 LYS   A NZ  1 
ATOM   1303 N N   . LEU   A 1 164 ? 17.50173  -22.95033 4.18344   1.000 54.24000  ? 378 LEU   A N   1 
ATOM   1304 C CA  . LEU   A 1 164 ? 16.41672  -23.17572 5.13134   1.000 50.65000  ? 378 LEU   A CA  1 
ATOM   1305 C C   . LEU   A 1 164 ? 15.91284  -24.60773 5.05388   1.000 51.78000  ? 378 LEU   A C   1 
ATOM   1306 O O   . LEU   A 1 164 ? 15.94387  -25.33504 6.04565   1.000 48.43000  ? 378 LEU   A O   1 
ATOM   1307 C CB  . LEU   A 1 164 ? 15.28065  -22.19773 4.86661   1.000 50.90000  ? 378 LEU   A CB  1 
ATOM   1308 C CG  . LEU   A 1 164 ? 14.42158  -21.82017 6.06070   1.000 50.00000  ? 378 LEU   A CG  1 
ATOM   1309 C CD1 . LEU   A 1 164 ? 15.19948  -20.96442 7.06599   1.000 48.34000  ? 378 LEU   A CD1 1 
ATOM   1310 C CD2 . LEU   A 1 164 ? 13.18054  -21.10711 5.56488   1.000 45.78000  ? 378 LEU   A CD2 1 
ATOM   1311 N N   . LYS   A 1 165 ? 15.45391  -25.02740 3.86873   1.000 54.68000  ? 379 LYS   A N   1 
ATOM   1312 C CA  . LYS   A 1 165 ? 14.97703  -26.39538 3.67129   1.000 57.36000  ? 379 LYS   A CA  1 
ATOM   1313 C C   . LYS   A 1 165 ? 15.95409  -27.42048 4.24100   1.000 58.80000  ? 379 LYS   A C   1 
ATOM   1314 O O   . LYS   A 1 165 ? 15.54215  -28.40770 4.86268   1.000 56.73000  ? 379 LYS   A O   1 
ATOM   1315 C CB  . LYS   A 1 165 ? 14.74009  -26.65093 2.17521   1.000 61.09000  ? 379 LYS   A CB  1 
ATOM   1316 C CG  . LYS   A 1 165 ? 13.46016  -27.39593 1.84793   1.000 67.70000  ? 379 LYS   A CG  1 
ATOM   1317 C CD  . LYS   A 1 165 ? 13.66429  -28.91289 1.74847   1.000 74.98000  ? 379 LYS   A CD  1 
ATOM   1318 C CE  . LYS   A 1 165 ? 12.33135  -29.58889 1.42222   1.000 84.42000  ? 379 LYS   A CE  1 
ATOM   1319 N NZ  . LYS   A 1 165 ? 12.40048  -30.96671 0.85379   1.000 87.15000  ? 379 LYS   A NZ  1 
ATOM   1320 N N   . HIS   A 1 166 ? 17.25908  -27.18132 4.06112   1.000 57.55000  ? 380 HIS   A N   1 
ATOM   1321 C CA  . HIS   A 1 166 ? 18.27714  -28.13437 4.49086   1.000 57.61000  ? 380 HIS   A CA  1 
ATOM   1322 C C   . HIS   A 1 166 ? 18.28811  -28.37584 6.00078   1.000 59.43000  ? 380 HIS   A C   1 
ATOM   1323 O O   . HIS   A 1 166 ? 18.84118  -29.39193 6.43748   1.000 61.97000  ? 380 HIS   A O   1 
ATOM   1324 C CB  . HIS   A 1 166 ? 19.66212  -27.65712 4.06005   1.000 59.19000  ? 380 HIS   A CB  1 
ATOM   1325 C CG  . HIS   A 1 166 ? 19.96918  -27.86464 2.60099   1.000 65.92000  ? 380 HIS   A CG  1 
ATOM   1326 N ND1 . HIS   A 1 166 ? 21.07315  -27.30036 1.99320   1.000 63.28000  ? 380 HIS   A ND1 1 
ATOM   1327 C CD2 . HIS   A 1 166 ? 19.32527  -28.56139 1.63075   1.000 65.85000  ? 380 HIS   A CD2 1 
ATOM   1328 C CE1 . HIS   A 1 166 ? 21.10122  -27.64696 0.71609   1.000 63.99000  ? 380 HIS   A CE1 1 
ATOM   1329 N NE2 . HIS   A 1 166 ? 20.05129  -28.41097 0.47182   1.000 69.35000  ? 380 HIS   A NE2 1 
ATOM   1330 N N   . LEU   A 1 167 ? 17.69802  -27.48113 6.80204   1.000 55.95000  ? 381 LEU   A N   1 
ATOM   1331 C CA  . LEU   A 1 167 ? 17.74698  -27.59158 8.26201   1.000 55.12000  ? 381 LEU   A CA  1 
ATOM   1332 C C   . LEU   A 1 167 ? 17.07007  -28.88478 8.71558   1.000 59.22000  ? 381 LEU   A C   1 
ATOM   1333 O O   . LEU   A 1 167 ? 16.00911  -29.23370 8.18544   1.000 60.41000  ? 381 LEU   A O   1 
ATOM   1334 C CB  . LEU   A 1 167 ? 17.05886  -26.38984 8.90936   1.000 51.55000  ? 381 LEU   A CB  1 
ATOM   1335 C CG  . LEU   A 1 167 ? 17.93876  -25.14882 9.06377   1.000 52.89000  ? 381 LEU   A CG  1 
ATOM   1336 C CD1 . LEU   A 1 167 ? 17.17565  -24.01208 9.72010   1.000 46.46000  ? 381 LEU   A CD1 1 
ATOM   1337 C CD2 . LEU   A 1 167 ? 19.16076  -25.49397 9.87970   1.000 49.54000  ? 381 LEU   A CD2 1 
ATOM   1338 N N   . PRO   A 1 168 ? 17.66010  -29.63203 9.65637   1.000 64.05000  ? 382 PRO   A N   1 
ATOM   1339 C CA  . PRO   A 1 168 ? 17.06619  -30.91920 10.05595  1.000 58.95000  ? 382 PRO   A CA  1 
ATOM   1340 C C   . PRO   A 1 168 ? 15.62617  -30.85946 10.52792  1.000 58.43000  ? 382 PRO   A C   1 
ATOM   1341 O O   . PRO   A 1 168 ? 14.90726  -31.84846 10.35259  1.000 60.85000  ? 382 PRO   A O   1 
ATOM   1342 C CB  . PRO   A 1 168 ? 18.00020  -31.39047 11.17683  1.000 61.15000  ? 382 PRO   A CB  1 
ATOM   1343 C CG  . PRO   A 1 168 ? 19.35216  -30.84624 10.77004  1.000 60.10000  ? 382 PRO   A CG  1 
ATOM   1344 C CD  . PRO   A 1 168 ? 19.10709  -29.58700 9.95543   1.000 59.51000  ? 382 PRO   A CD  1 
ATOM   1345 N N   . GLU   A 1 169 ? 15.16507  -29.74567 11.09526  1.000 56.44000  ? 383 GLU   A N   1 
ATOM   1346 C CA  . GLU   A 1 169 ? 13.96004  -29.72303 11.91223  1.000 56.70000  ? 383 GLU   A CA  1 
ATOM   1347 C C   . GLU   A 1 169 ? 13.11195  -28.47802 11.65759  1.000 57.36000  ? 383 GLU   A C   1 
ATOM   1348 O O   . GLU   A 1 169 ? 13.64086  -27.37292 11.50195  1.000 54.34000  ? 383 GLU   A O   1 
ATOM   1349 C CB  . GLU   A 1 169 ? 14.34000  -29.77746 13.40522  1.000 58.13000  ? 383 GLU   A CB  1 
ATOM   1350 C CG  . GLU   A 1 169 ? 15.10408  -31.02553 13.81386  1.000 60.65000  ? 383 GLU   A CG  1 
ATOM   1351 C CD  . GLU   A 1 169 ? 14.24318  -32.27760 13.81744  1.000 65.76000  ? 383 GLU   A CD  1 
ATOM   1352 O OE1 . GLU   A 1 169 ? 12.99217  -32.15571 13.85244  1.000 65.28000  ? 383 GLU   A OE1 1 
ATOM   1353 O OE2 . GLU   A 1 169 ? 14.83028  -33.38654 13.77811  1.000 73.15000  ? 383 GLU   A OE2 1 
ATOM   1354 N N   . LYS   A 1 170 ? 11.78596  -28.64613 11.68849  1.000 54.05000  ? 384 LYS   A N   1 
ATOM   1355 C CA  . LYS   A 1 170 ? 10.92687  -27.49113 11.46583  1.000 55.71000  ? 384 LYS   A CA  1 
ATOM   1356 C C   . LYS   A 1 170 ? 11.08775  -26.43646 12.56616  1.000 58.72000  ? 384 LYS   A C   1 
ATOM   1357 O O   . LYS   A 1 170 ? 10.97466  -25.23338 12.28753  1.000 59.88000  ? 384 LYS   A O   1 
ATOM   1358 C CB  . LYS   A 1 170 ? 9.46691   -27.93221 11.33764  1.000 61.65000  ? 384 LYS   A CB  1 
ATOM   1359 C CG  . LYS   A 1 170 ? 9.25803   -28.99290 10.28231  1.000 63.42000  ? 384 LYS   A CG  1 
ATOM   1360 C CD  . LYS   A 1 170 ? 8.84902   -28.37152 8.96649   1.000 71.33000  ? 384 LYS   A CD  1 
ATOM   1361 C CE  . LYS   A 1 170 ? 8.39414   -29.43025 7.97614   1.000 78.90000  ? 384 LYS   A CE  1 
ATOM   1362 N NZ  . LYS   A 1 170 ? 6.91515   -29.64439 8.03103   1.000 88.97000  ? 384 LYS   A NZ  1 
ATOM   1363 N N   . TYR   A 1 171 ? 11.35975  -26.84483 13.81404  1.000 53.91000  ? 385 TYR   A N   1 
ATOM   1364 C CA  . TYR   A 1 171 ? 11.49063  -25.83414 14.86636  1.000 58.49000  ? 385 TYR   A CA  1 
ATOM   1365 C C   . TYR   A 1 171 ? 12.73157  -24.98098 14.64566  1.000 58.76000  ? 385 TYR   A C   1 
ATOM   1366 O O   . TYR   A 1 171 ? 12.76846  -23.81110 15.05403  1.000 59.37000  ? 385 TYR   A O   1 
ATOM   1367 C CB  . TYR   A 1 171 ? 11.49364  -26.47058 16.27316  1.000 53.82000  ? 385 TYR   A CB  1 
ATOM   1368 C CG  . TYR   A 1 171 ? 12.67670  -27.36958 16.58492  1.000 57.76000  ? 385 TYR   A CG  1 
ATOM   1369 C CD1 . TYR   A 1 171 ? 13.91065  -26.83961 16.98812  1.000 56.52000  ? 385 TYR   A CD1 1 
ATOM   1370 C CD2 . TYR   A 1 171 ? 12.56282  -28.75256 16.48949  1.000 57.55000  ? 385 TYR   A CD2 1 
ATOM   1371 C CE1 . TYR   A 1 171 ? 14.99371  -27.67361 17.26590  1.000 56.21000  ? 385 TYR   A CE1 1 
ATOM   1372 C CE2 . TYR   A 1 171 ? 13.64188  -29.59056 16.77126  1.000 57.15000  ? 385 TYR   A CE2 1 
ATOM   1373 C CZ  . TYR   A 1 171 ? 14.84682  -29.04559 17.15047  1.000 55.74000  ? 385 TYR   A CZ  1 
ATOM   1374 O OH  . TYR   A 1 171 ? 15.89988  -29.88059 17.42524  1.000 59.12000  ? 385 TYR   A OH  1 
ATOM   1375 N N   . MET   A 1 172 ? 13.75163  -25.52269 13.98653  1.000 53.83000  ? 386 MET   A N   1 
ATOM   1376 C CA  . MET   A 1 172 ? 14.86657  -24.65549 13.64783  1.000 56.13000  ? 386 MET   A CA  1 
ATOM   1377 C C   . MET   A 1 172 ? 14.50654  -23.74016 12.48611  1.000 56.22000  ? 386 MET   A C   1 
ATOM   1378 O O   . MET   A 1 172 ? 14.93144  -22.58012 12.46848  1.000 57.26000  ? 386 MET   A O   1 
ATOM   1379 C CB  . MET   A 1 172 ? 16.11865  -25.46430 13.33762  1.000 51.70000  ? 386 MET   A CB  1 
ATOM   1380 C CG  . MET   A 1 172 ? 16.37871  -26.56058 14.30529  1.000 48.27000  ? 386 MET   A CG  1 
ATOM   1381 S SD  . MET   A 1 172 ? 17.93178  -27.31631 13.86910  1.000 65.19000  ? 386 MET   A SD  1 
ATOM   1382 C CE  . MET   A 1 172 ? 17.41590  -28.23292 12.47580  1.000 58.65000  ? 386 MET   A CE  1 
ATOM   1383 N N   . MET   A 1 173 ? 13.71161  -24.21892 11.51393  1.000 54.27000  ? 387 MET   A N   1 
ATOM   1384 C CA  . MET   A 1 173 ? 13.24456  -23.29164 10.48321  1.000 53.41000  ? 387 MET   A CA  1 
ATOM   1385 C C   . MET   A 1 173 ? 12.49845  -22.11489 11.10155  1.000 52.60000  ? 387 MET   A C   1 
ATOM   1386 O O   . MET   A 1 173 ? 12.63037  -20.97274 10.63691  1.000 47.07000  ? 387 MET   A O   1 
ATOM   1387 C CB  . MET   A 1 173 ? 12.36165  -23.99839 9.45096   1.000 56.31000  ? 387 MET   A CB  1 
ATOM   1388 C CG  . MET   A 1 173 ? 13.09476  -24.87801 8.41971   1.000 58.63000  ? 387 MET   A CG  1 
ATOM   1389 S SD  . MET   A 1 173 ? 12.07189  -26.24290 7.80625   1.000 56.36000  ? 387 MET   A SD  1 
ATOM   1390 C CE  . MET   A 1 173 ? 13.27099  -27.21553 6.92799   1.000 47.38000  ? 387 MET   A CE  1 
ATOM   1391 N N   . ASN   A 1 174 ? 11.74044  -22.36629 12.17245  1.000 49.92000  ? 388 ASN   A N   1 
ATOM   1392 C CA  . ASN   A 1 174 ? 10.95833  -21.29753 12.76876  1.000 53.94000  ? 388 ASN   A CA  1 
ATOM   1393 C C   . ASN   A 1 174 ? 11.82923  -20.32270 13.53909  1.000 55.97000  ? 388 ASN   A C   1 
ATOM   1394 O O   . ASN   A 1 174 ? 11.55013  -19.11772 13.52645  1.000 56.88000  ? 388 ASN   A O   1 
ATOM   1395 C CB  . ASN   A 1 174 ? 9.87035   -21.87390 13.66654  1.000 62.38000  ? 388 ASN   A CB  1 
ATOM   1396 C CG  . ASN   A 1 174 ? 8.58340   -22.14977 12.90742  1.000 62.63000  ? 388 ASN   A CG  1 
ATOM   1397 O OD1 . ASN   A 1 174 ? 8.34839   -21.60445 11.82458  1.000 61.35000  ? 388 ASN   A OD1 1 
ATOM   1398 N ND2 . ASN   A 1 174 ? 7.75145   -23.01201 13.46112  1.000 67.73000  ? 388 ASN   A ND2 1 
ATOM   1399 N N   . SER   A 1 175 ? 12.88425  -20.81082 14.20097  1.000 54.28000  ? 389 SER   A N   1 
ATOM   1400 C CA  . SER   A 1 175 ? 13.80115  -19.92297 14.90827  1.000 52.28000  ? 389 SER   A CA  1 
ATOM   1401 C C   . SER   A 1 175 ? 14.51911  -18.96861 13.94459  1.000 53.09000  ? 389 SER   A C   1 
ATOM   1402 O O   . SER   A 1 175 ? 14.76000  -17.79970 14.27496  1.000 52.70000  ? 389 SER   A O   1 
ATOM   1403 C CB  . SER   A 1 175 ? 14.79820  -20.76114 15.70604  1.000 59.54000  ? 389 SER   A CB  1 
ATOM   1404 O OG  . SER   A 1 175 ? 15.37410  -20.00342 16.74930  1.000 65.19000  ? 389 SER   A OG  1 
ATOM   1405 N N   . VAL   A 1 176 ? 14.86118  -19.44121 12.74445  1.000 55.19000  ? 390 VAL   A N   1 
ATOM   1406 C CA  . VAL   A 1 176 ? 15.44014  -18.55285 11.74075  1.000 54.37000  ? 390 VAL   A CA  1 
ATOM   1407 C C   . VAL   A 1 176 ? 14.42207  -17.51179 11.28804  1.000 50.84000  ? 390 VAL   A C   1 
ATOM   1408 O O   . VAL   A 1 176 ? 14.69097  -16.30178 11.32543  1.000 46.59000  ? 390 VAL   A O   1 
ATOM   1409 C CB  . VAL   A 1 176 ? 15.98324  -19.35944 10.55152  1.000 50.92000  ? 390 VAL   A CB  1 
ATOM   1410 C CG1 . VAL   A 1 176 ? 16.44820  -18.41506 9.46582   1.000 47.33000  ? 390 VAL   A CG1 1 
ATOM   1411 C CG2 . VAL   A 1 176 ? 17.13230  -20.23648 10.99128  1.000 46.03000  ? 390 VAL   A CG2 1 
ATOM   1412 N N   . LEU   A 1 177 ? 13.22812  -17.96876 10.87486  1.000 49.79000  ? 391 LEU   A N   1 
ATOM   1413 C CA  . LEU   A 1 177 ? 12.20407  -17.10266 10.28310  1.000 50.26000  ? 391 LEU   A CA  1 
ATOM   1414 C C   . LEU   A 1 177 ? 11.73195  -15.99899 11.23643  1.000 55.25000  ? 391 LEU   A C   1 
ATOM   1415 O O   . LEU   A 1 177 ? 11.16089  -15.00590 10.77272  1.000 56.08000  ? 391 LEU   A O   1 
ATOM   1416 C CB  . LEU   A 1 177 ? 11.01215  -17.96061 9.81380   1.000 47.01000  ? 391 LEU   A CB  1 
ATOM   1417 C CG  . LEU   A 1 177 ? 11.21126  -18.84220 8.56253   1.000 55.95000  ? 391 LEU   A CG  1 
ATOM   1418 C CD1 . LEU   A 1 177 ? 10.00135  -19.73822 8.29121   1.000 53.90000  ? 391 LEU   A CD1 1 
ATOM   1419 C CD2 . LEU   A 1 177 ? 11.57724  -18.03578 7.28879   1.000 43.88000  ? 391 LEU   A CD2 1 
ATOM   1420 N N   . GLU   A 1 178 ? 11.99292  -16.11837 12.52140  1.000 56.98000  ? 392 GLU   A N   1 
ATOM   1421 C CA  . GLU   A 1 178 ? 11.58481  -15.09870 13.45870  1.000 54.29000  ? 392 GLU   A CA  1 
ATOM   1422 C C   . GLU   A 1 178 ? 12.20071  -13.75656 13.15914  1.000 55.15000  ? 392 GLU   A C   1 
ATOM   1423 O O   . GLU   A 1 178 ? 11.60362  -12.73569 13.42944  1.000 55.37000  ? 392 GLU   A O   1 
ATOM   1424 C CB  . GLU   A 1 178 ? 11.94980  -15.51211 14.87059  1.000 52.14000  ? 392 GLU   A CB  1 
ATOM   1425 C CG  . GLU   A 1 178 ? 10.81883  -16.17344 15.63035  1.000 63.89000  ? 392 GLU   A CG  1 
ATOM   1426 C CD  . GLU   A 1 178 ? 9.95672   -15.16173 16.35263  1.000 77.89000  ? 392 GLU   A CD  1 
ATOM   1427 O OE1 . GLU   A 1 178 ? 10.45463  -14.05077 16.62200  1.000 75.65000  ? 392 GLU   A OE1 1 
ATOM   1428 O OE2 . GLU   A 1 178 ? 8.78774   -15.47692 16.66250  1.000 71.18000  ? 392 GLU   A OE2 1 
ATOM   1429 N N   . ASN   A 1 179 ? 13.40273  -13.75729 12.61818  1.000 54.58000  ? 393 ASN   A N   1 
ATOM   1430 C CA  . ASN   A 1 179 ? 14.07164  -12.50813 12.28659  1.000 50.02000  ? 393 ASN   A CA  1 
ATOM   1431 C C   . ASN   A 1 179 ? 14.18967  -12.31166 10.78865  1.000 50.39000  ? 393 ASN   A C   1 
ATOM   1432 O O   . ASN   A 1 179 ? 15.01562  -11.51245 10.32893  1.000 54.55000  ? 393 ASN   A O   1 
ATOM   1433 C CB  . ASN   A 1 179 ? 15.43061  -12.45824 12.97165  1.000 54.41000  ? 393 ASN   A CB  1 
ATOM   1434 C CG  . ASN   A 1 179 ? 15.28756  -12.39772 14.47666  1.000 56.46000  ? 393 ASN   A CG  1 
ATOM   1435 O OD1 . ASN   A 1 179 ? 14.95146  -11.34892 15.04098  1.000 54.90000  ? 393 ASN   A OD1 1 
ATOM   1436 N ND2 . ASN   A 1 179 ? 15.45663  -13.54791 15.12931  1.000 49.84000  ? 393 ASN   A ND2 1 
ATOM   1437 N N   . PHE   A 1 180 ? 13.36675  -13.02349 10.02741  1.000 50.12000  ? 394 PHE   A N   1 
ATOM   1438 C CA  . PHE   A 1 180 ? 13.24878  -12.86405 8.58545   1.000 52.05000  ? 394 PHE   A CA  1 
ATOM   1439 C C   . PHE   A 1 180 ? 11.91974  -12.17606 8.28162   1.000 48.56000  ? 394 PHE   A C   1 
ATOM   1440 O O   . PHE   A 1 180 ? 10.86876  -12.60830 8.76446   1.000 45.42000  ? 394 PHE   A O   1 
ATOM   1441 C CB  . PHE   A 1 180 ? 13.34291  -14.21682 7.88203   1.000 51.27000  ? 394 PHE   A CB  1 
ATOM   1442 C CG  . PHE   A 1 180 ? 13.32395  -14.11536 6.39106   1.000 51.46000  ? 394 PHE   A CG  1 
ATOM   1443 C CD1 . PHE   A 1 180 ? 14.46794  -13.76305 5.69721   1.000 47.42000  ? 394 PHE   A CD1 1 
ATOM   1444 C CD2 . PHE   A 1 180 ? 12.14999  -14.34023 5.68496   1.000 47.33000  ? 394 PHE   A CD2 1 
ATOM   1445 C CE1 . PHE   A 1 180 ? 14.45398  -13.65962 4.30724   1.000 49.49000  ? 394 PHE   A CE1 1 
ATOM   1446 C CE2 . PHE   A 1 180 ? 12.12802  -14.22580 4.29799   1.000 54.02000  ? 394 PHE   A CE2 1 
ATOM   1447 C CZ  . PHE   A 1 180 ? 13.28202  -13.88650 3.60813   1.000 49.69000  ? 394 PHE   A CZ  1 
ATOM   1448 N N   . THR   A 1 181 ? 11.97767  -11.09381 7.50996   1.000 46.22000  ? 395 THR   A N   1 
ATOM   1449 C CA  . THR   A 1 181 ? 10.79762  -10.32880 7.14816   1.000 45.47000  ? 395 THR   A CA  1 
ATOM   1450 C C   . THR   A 1 181 ? 10.96762  -9.78734  5.73434   1.000 52.00000  ? 395 THR   A C   1 
ATOM   1451 O O   . THR   A 1 181 ? 12.08563  -9.65809  5.21341   1.000 52.00000  ? 395 THR   A O   1 
ATOM   1452 C CB  . THR   A 1 181 ? 10.54350  -9.14411  8.09153   1.000 47.97000  ? 395 THR   A CB  1 
ATOM   1453 O OG1 . THR   A 1 181 ? 11.68643  -8.28203  8.11483   1.000 51.30000  ? 395 THR   A OG1 1 
ATOM   1454 C CG2 . THR   A 1 181 ? 10.23449  -9.61457  9.49937   1.000 43.04000  ? 395 THR   A CG2 1 
ATOM   1455 N N   . ILE   A 1 182 ? 9.84262   -9.46524  5.11840   1.000 46.85000  ? 396 ILE   A N   1 
ATOM   1456 C CA  . ILE   A 1 182 ? 9.83460   -8.77585  3.83962   1.000 50.75000  ? 396 ILE   A CA  1 
ATOM   1457 C C   . ILE   A 1 182 ? 8.88250   -7.60097  3.98495   1.000 46.25000  ? 396 ILE   A C   1 
ATOM   1458 O O   . ILE   A 1 182 ? 7.83949   -7.72725  4.62888   1.000 45.50000  ? 396 ILE   A O   1 
ATOM   1459 C CB  . ILE   A 1 182 ? 9.40971   -9.70752  2.68131   1.000 48.53000  ? 396 ILE   A CB  1 
ATOM   1460 C CG1 . ILE   A 1 182 ? 10.54080  -10.63530 2.25806   1.000 46.97000  ? 396 ILE   A CG1 1 
ATOM   1461 C CG2 . ILE   A 1 182 ? 9.02568   -8.90218  1.48555   1.000 48.54000  ? 396 ILE   A CG2 1 
ATOM   1462 C CD1 . ILE   A 1 182 ? 10.06392  -12.02624 1.95661   1.000 45.26000  ? 396 ILE   A CD1 1 
ATOM   1463 N N   . LEU   A 1 183 ? 9.25342   -6.44977  3.43832   1.000 44.25000  ? 397 LEU   A N   1 
ATOM   1464 C CA  . LEU   A 1 183 ? 8.38433   -5.28084  3.44466   1.000 48.56000  ? 397 LEU   A CA  1 
ATOM   1465 C C   . LEU   A 1 183 ? 8.04034   -4.89742  2.00777   1.000 53.36000  ? 397 LEU   A C   1 
ATOM   1466 O O   . LEU   A 1 183 ? 8.94535   -4.67709  1.18687   1.000 54.20000  ? 397 LEU   A O   1 
ATOM   1467 C CB  . LEU   A 1 183 ? 9.04121   -4.10701  4.17305   1.000 44.04000  ? 397 LEU   A CB  1 
ATOM   1468 C CG  . LEU   A 1 183 ? 8.16211   -2.86913  4.31640   1.000 46.39000  ? 397 LEU   A CG  1 
ATOM   1469 C CD1 . LEU   A 1 183 ? 7.01010   -3.14751  5.24628   1.000 42.77000  ? 397 LEU   A CD1 1 
ATOM   1470 C CD2 . LEU   A 1 183 ? 8.97500   -1.68021  4.79380   1.000 42.87000  ? 397 LEU   A CD2 1 
ATOM   1471 N N   . GLN   A 1 184 ? 6.74135   -4.80843  1.70676   1.000 48.63000  ? 398 GLN   A N   1 
ATOM   1472 C CA  . GLN   A 1 184 ? 6.27635   -4.38506  0.38987   1.000 49.69000  ? 398 GLN   A CA  1 
ATOM   1473 C C   . GLN   A 1 184 ? 5.62524   -3.01714  0.47128   1.000 46.12000  ? 398 GLN   A C   1 
ATOM   1474 O O   . GLN   A 1 184 ? 4.74420   -2.79047  1.30132   1.000 51.31000  ? 398 GLN   A O   1 
ATOM   1475 C CB  . GLN   A 1 184 ? 5.28745   -5.36795  -0.22346  1.000 48.53000  ? 398 GLN   A CB  1 
ATOM   1476 C CG  . GLN   A 1 184 ? 5.03647   -5.02152  -1.65836  1.000 44.03000  ? 398 GLN   A CG  1 
ATOM   1477 C CD  . GLN   A 1 184 ? 4.31758   -6.11335  -2.39273  1.000 50.03000  ? 398 GLN   A CD  1 
ATOM   1478 O OE1 . GLN   A 1 184 ? 3.18860   -6.47255  -2.06087  1.000 53.29000  ? 398 GLN   A OE1 1 
ATOM   1479 N NE2 . GLN   A 1 184 ? 4.97065   -6.65898  -3.40488  1.000 59.07000  ? 398 GLN   A NE2 1 
ATOM   1480 N N   . VAL   A 1 185 ? 6.05619   -2.12383  -0.40443  1.000 46.15000  ? 399 VAL   A N   1 
ATOM   1481 C CA  . VAL   A 1 185 ? 5.56909   -0.75584  -0.48102  1.000 44.70000  ? 399 VAL   A CA  1 
ATOM   1482 C C   . VAL   A 1 185 ? 5.29011   -0.45841  -1.94494  1.000 46.28000  ? 399 VAL   A C   1 
ATOM   1483 O O   . VAL   A 1 185 ? 6.22212   -0.27809  -2.74385  1.000 41.60000  ? 399 VAL   A O   1 
ATOM   1484 C CB  . VAL   A 1 185 ? 6.56599   0.25205   0.10433   1.000 45.21000  ? 399 VAL   A CB  1 
ATOM   1485 C CG1 . VAL   A 1 185 ? 6.02988   1.66006   -0.04325  1.000 45.70000  ? 399 VAL   A CG1 1 
ATOM   1486 C CG2 . VAL   A 1 185 ? 6.80597   -0.06339  1.58923   1.000 51.33000  ? 399 VAL   A CG2 1 
ATOM   1487 N N   . VAL   A 1 186 ? 4.01312   -0.42740  -2.29797  1.000 46.19000  ? 400 VAL   A N   1 
ATOM   1488 C CA  . VAL   A 1 186 ? 3.56813   -0.04303  -3.62686  1.000 49.16000  ? 400 VAL   A CA  1 
ATOM   1489 C C   . VAL   A 1 186 ? 3.28001   1.44594   -3.59641  1.000 49.54000  ? 400 VAL   A C   1 
ATOM   1490 O O   . VAL   A 1 186 ? 2.57394   1.92961   -2.70528  1.000 51.04000  ? 400 VAL   A O   1 
ATOM   1491 C CB  . VAL   A 1 186 ? 2.32520   -0.83800  -4.04915  1.000 49.03000  ? 400 VAL   A CB  1 
ATOM   1492 C CG1 . VAL   A 1 186 ? 2.01823   -0.58256  -5.53008  1.000 43.57000  ? 400 VAL   A CG1 1 
ATOM   1493 C CG2 . VAL   A 1 186 ? 2.49831   -2.32308  -3.72660  1.000 43.53000  ? 400 VAL   A CG2 1 
ATOM   1494 N N   . THR   A 1 187 ? 3.84498   2.18028   -4.53916  1.000 49.71000  ? 401 THR   A N   1 
ATOM   1495 C CA  . THR   A 1 187 ? 3.52987   3.59030   -4.67573  1.000 58.60000  ? 401 THR   A CA  1 
ATOM   1496 C C   . THR   A 1 187 ? 3.11189   3.84971   -6.11466  1.000 59.58000  ? 401 THR   A C   1 
ATOM   1497 O O   . THR   A 1 187 ? 3.41498   3.05601   -7.00790  1.000 58.68000  ? 401 THR   A O   1 
ATOM   1498 C CB  . THR   A 1 187 ? 4.71578   4.49127   -4.27141  1.000 54.77000  ? 401 THR   A CB  1 
ATOM   1499 O OG1 . THR   A 1 187 ? 5.82783   4.23963   -5.13546  1.000 57.51000  ? 401 THR   A OG1 1 
ATOM   1500 C CG2 . THR   A 1 187 ? 5.12876   4.20786   -2.85149  1.000 51.73000  ? 401 THR   A CG2 1 
ATOM   1501 N N   . SER   A 1 188 ? 2.35381   4.92971   -6.32235  1.000 62.70000  ? 402 SER   A N   1 
ATOM   1502 C CA  . SER   A 1 188 ? 2.17381   5.45512   -7.67019  1.000 64.73000  ? 402 SER   A CA  1 
ATOM   1503 C C   . SER   A 1 188 ? 3.50078   6.03037   -8.13597  1.000 64.20000  ? 402 SER   A C   1 
ATOM   1504 O O   . SER   A 1 188 ? 4.14770   6.76919   -7.38872  1.000 68.15000  ? 402 SER   A O   1 
ATOM   1505 C CB  . SER   A 1 188 ? 1.08572   6.52504   -7.69589  1.000 66.71000  ? 402 SER   A CB  1 
ATOM   1506 O OG  . SER   A 1 188 ? 1.24969   7.36840   -8.82263  1.000 72.52000  ? 402 SER   A OG  1 
ATOM   1507 N N   . ARG   A 1 189 ? 3.92684   5.67278   -9.35107  1.000 58.79000  ? 403 ARG   A N   1 
ATOM   1508 C CA  . ARG   A 1 189 ? 5.33084   5.87001   -9.69696  1.000 64.78000  ? 403 ARG   A CA  1 
ATOM   1509 C C   . ARG   A 1 189 ? 5.69872   7.35104   -9.72849  1.000 70.97000  ? 403 ARG   A C   1 
ATOM   1510 O O   . ARG   A 1 189 ? 6.66467   7.77792   -9.07733  1.000 72.25000  ? 403 ARG   A O   1 
ATOM   1511 C CB  . ARG   A 1 189 ? 5.65694   5.19545   -11.02916 1.000 59.88000  ? 403 ARG   A CB  1 
ATOM   1512 C CG  . ARG   A 1 189 ? 7.16195   5.06365   -11.28616 1.000 61.94000  ? 403 ARG   A CG  1 
ATOM   1513 C CD  . ARG   A 1 189 ? 7.44004   4.56911   -12.70230 1.000 68.86000  ? 403 ARG   A CD  1 
ATOM   1514 N NE  . ARG   A 1 189 ? 6.92099   5.53437   -13.66302 1.000 71.60000  ? 403 ARG   A NE  1 
ATOM   1515 C CZ  . ARG   A 1 189 ? 6.75405   5.31376   -14.95809 1.000 70.73000  ? 403 ARG   A CZ  1 
ATOM   1516 N NH1 . ARG   A 1 189 ? 7.08016   4.15896   -15.51644 1.000 69.69000  ? 403 ARG   A NH1 1 
ATOM   1517 N NH2 . ARG   A 1 189 ? 6.22799   6.27395   -15.71081 1.000 73.63000  ? 403 ARG   A NH2 1 
ATOM   1518 N N   . ASP   A 1 190 ? 4.91868   8.13520   -10.43327 1.000 72.36000  ? 404 ASP   A N   1 
ATOM   1519 C CA  . ASP   A 1 190 ? 5.26657   9.52728   -10.58883 1.000 73.74000  ? 404 ASP   A CA  1 
ATOM   1520 C C   . ASP   A 1 190 ? 4.92546   10.39788  -9.38457  1.000 71.13000  ? 404 ASP   A C   1 
ATOM   1521 O O   . ASP   A 1 190 ? 5.64138   11.34184  -9.08625  1.000 67.41000  ? 404 ASP   A O   1 
ATOM   1522 C CB  . ASP   A 1 190 ? 4.58257   10.04261  -11.84269 1.000 80.30000  ? 404 ASP   A CB  1 
ATOM   1523 C CG  . ASP   A 1 190 ? 4.93367   9.23002   -13.06393 1.000 87.52000  ? 404 ASP   A CG  1 
ATOM   1524 O OD1 . ASP   A 1 190 ? 5.85374   8.39407   -12.96816 1.000 91.00000  ? 404 ASP   A OD1 1 
ATOM   1525 O OD2 . ASP   A 1 190 ? 4.29569   9.42630   -14.11789 1.000 88.93000  ? 404 ASP   A OD2 1 
ATOM   1526 N N   . SER   A 1 191 ? 3.84847   10.07657  -8.69070  1.000 67.60000  ? 405 SER   A N   1 
ATOM   1527 C CA  . SER   A 1 191 ? 3.48137   10.84717  -7.50747  1.000 64.48000  ? 405 SER   A CA  1 
ATOM   1528 C C   . SER   A 1 191 ? 4.27937   10.40686  -6.28259  1.000 65.01000  ? 405 SER   A C   1 
ATOM   1529 O O   . SER   A 1 191 ? 4.63927   11.23963  -5.44131  1.000 61.63000  ? 405 SER   A O   1 
ATOM   1530 C CB  . SER   A 1 191 ? 1.97337   10.74398  -7.26255  1.000 63.07000  ? 405 SER   A CB  1 
ATOM   1531 O OG  . SER   A 1 191 ? 1.62342   9.75465   -6.30787  1.000 63.80000  ? 405 SER   A OG  1 
ATOM   1532 N N   . GLN   A 1 192 ? 4.57647   9.11185   -6.17398  1.000 61.82000  ? 406 GLN   A N   1 
ATOM   1533 C CA  . GLN   A 1 192 ? 5.25049   8.46455   -5.05116  1.000 61.78000  ? 406 GLN   A CA  1 
ATOM   1534 C C   . GLN   A 1 192 ? 4.34646   8.35410   -3.82922  1.000 63.58000  ? 406 GLN   A C   1 
ATOM   1535 O O   . GLN   A 1 192 ? 4.77347   7.80581   -2.80338  1.000 63.01000  ? 406 GLN   A O   1 
ATOM   1536 C CB  . GLN   A 1 192 ? 6.57542   9.14854   -4.68091  1.000 58.02000  ? 406 GLN   A CB  1 
ATOM   1537 C CG  . GLN   A 1 192 ? 7.55245   9.18999   -5.84386  1.000 65.34000  ? 406 GLN   A CG  1 
ATOM   1538 C CD  . GLN   A 1 192 ? 9.00043   9.26697   -5.40879  1.000 68.71000  ? 406 GLN   A CD  1 
ATOM   1539 O OE1 . GLN   A 1 192 ? 9.30837   9.62864   -4.27367  1.000 64.65000  ? 406 GLN   A OE1 1 
ATOM   1540 N NE2 . GLN   A 1 192 ? 9.90349   8.92132   -6.31987  1.000 71.61000  ? 406 GLN   A NE2 1 
ATOM   1541 N N   . GLU   A 1 193 ? 3.11042   8.82903   -3.91011  1.000 60.30000  ? 407 GLU   A N   1 
ATOM   1542 C CA  . GLU   A 1 193 ? 2.13541   8.55862   -2.86923  1.000 63.44000  ? 407 GLU   A CA  1 
ATOM   1543 C C   . GLU   A 1 193 ? 2.10852   7.06752   -2.53369  1.000 64.91000  ? 407 GLU   A C   1 
ATOM   1544 O O   . GLU   A 1 193 ? 2.17562   6.21680   -3.42495  1.000 63.10000  ? 407 GLU   A O   1 
ATOM   1545 C CB  . GLU   A 1 193 ? 0.74939   9.02765   -3.32812  1.000 64.67000  ? 407 GLU   A CB  1 
ATOM   1546 C CG  . GLU   A 1 193 ? -0.41860  8.55129   -2.44831  1.000 63.43000  ? 407 GLU   A CG  1 
ATOM   1547 C CD  . GLU   A 1 193 ? -1.72257  8.41942   -3.21939  1.000 64.05000  ? 407 GLU   A CD  1 
ATOM   1548 O OE1 . GLU   A 1 193 ? -1.73555  8.65480   -4.45132  1.000 58.70000  ? 407 GLU   A OE1 1 
ATOM   1549 O OE2 . GLU   A 1 193 ? -2.74656  8.08914   -2.57753  1.000 71.11000  ? 407 GLU   A OE2 1 
ATOM   1550 N N   . THR   A 1 194 ? 2.01650   6.76110   -1.23779  1.000 65.82000  ? 408 THR   A N   1 
ATOM   1551 C CA  . THR   A 1 194 ? 1.91260   5.37796   -0.78822  1.000 59.68000  ? 408 THR   A CA  1 
ATOM   1552 C C   . THR   A 1 194 ? 0.52766   4.82494   -1.10144  1.000 55.90000  ? 408 THR   A C   1 
ATOM   1553 O O   . THR   A 1 194 ? -0.48540  5.42375   -0.73228  1.000 61.08000  ? 408 THR   A O   1 
ATOM   1554 C CB  . THR   A 1 194 ? 2.19556   5.28451   0.71376   1.000 62.84000  ? 408 THR   A CB  1 
ATOM   1555 O OG1 . THR   A 1 194 ? 3.55853   5.64454   0.96691   1.000 58.19000  ? 408 THR   A OG1 1 
ATOM   1556 C CG2 . THR   A 1 194 ? 1.91666   3.87532   1.24931   1.000 55.56000  ? 408 THR   A CG2 1 
ATOM   1557 N N   . LEU   A 1 195 ? 0.48577   3.67715   -1.77880  1.000 54.19000  ? 409 LEU   A N   1 
ATOM   1558 C CA  . LEU   A 1 195 ? -0.76417  3.01516   -2.14104  1.000 51.68000  ? 409 LEU   A CA  1 
ATOM   1559 C C   . LEU   A 1 195 ? -1.08210  1.82586   -1.25142  1.000 48.24000  ? 409 LEU   A C   1 
ATOM   1560 O O   . LEU   A 1 195 ? -2.21310  1.69062   -0.79150  1.000 53.64000  ? 409 LEU   A O   1 
ATOM   1561 C CB  . LEU   A 1 195 ? -0.72608  2.54262   -3.59719  1.000 53.21000  ? 409 LEU   A CB  1 
ATOM   1562 C CG  . LEU   A 1 195 ? -0.40313  3.59397   -4.63685  1.000 54.68000  ? 409 LEU   A CG  1 
ATOM   1563 C CD1 . LEU   A 1 195 ? -0.22304  2.93941   -6.00505  1.000 55.37000  ? 409 LEU   A CD1 1 
ATOM   1564 C CD2 . LEU   A 1 195 ? -1.55321  4.58887   -4.63058  1.000 53.22000  ? 409 LEU   A CD2 1 
ATOM   1565 N N   . LEU   A 1 196 ? -0.12203  0.93787   -1.04467  1.000 51.05000  ? 410 LEU   A N   1 
ATOM   1566 C CA  . LEU   A 1 196 ? -0.31996  -0.26039  -0.24305  1.000 50.21000  ? 410 LEU   A CA  1 
ATOM   1567 C C   . LEU   A 1 196 ? 1.01104   -0.57549  0.40589   1.000 56.41000  ? 410 LEU   A C   1 
ATOM   1568 O O   . LEU   A 1 196 ? 2.05406   -0.49820  -0.25005  1.000 56.80000  ? 410 LEU   A O   1 
ATOM   1569 C CB  . LEU   A 1 196 ? -0.78284  -1.46017  -1.07644  1.000 52.22000  ? 410 LEU   A CB  1 
ATOM   1570 C CG  . LEU   A 1 196 ? -1.63577  -2.52946  -0.38080  1.000 53.42000  ? 410 LEU   A CG  1 
ATOM   1571 C CD1 . LEU   A 1 196 ? -2.90184  -1.92375  0.22935   1.000 53.35000  ? 410 LEU   A CD1 1 
ATOM   1572 C CD2 . LEU   A 1 196 ? -2.00365  -3.64418  -1.35515  1.000 54.65000  ? 410 LEU   A CD2 1 
ATOM   1573 N N   . VAL   A 1 197 ? 0.97903   -0.90089  1.69379   1.000 55.28000  ? 411 VAL   A N   1 
ATOM   1574 C CA  . VAL   A 1 197 ? 2.15405   -1.37602  2.40068   1.000 48.56000  ? 411 VAL   A CA  1 
ATOM   1575 C C   . VAL   A 1 197 ? 1.74813   -2.66027  3.10027   1.000 50.62000  ? 411 VAL   A C   1 
ATOM   1576 O O   . VAL   A 1 197 ? 0.70711   -2.70156  3.76022   1.000 50.89000  ? 411 VAL   A O   1 
ATOM   1577 C CB  . VAL   A 1 197 ? 2.68693   -0.34429  3.40302   1.000 50.04000  ? 411 VAL   A CB  1 
ATOM   1578 C CG1 . VAL   A 1 197 ? 3.80496   -0.95945  4.22086   1.000 51.72000  ? 411 VAL   A CG1 1 
ATOM   1579 C CG2 . VAL   A 1 197 ? 3.16986   0.88898   2.68542   1.000 49.35000  ? 411 VAL   A CG2 1 
ATOM   1580 N N   . ILE   A 1 198 ? 2.53122   -3.71815  2.91896   1.000 51.71000  ? 412 ILE   A N   1 
ATOM   1581 C CA  . ILE   A 1 198 ? 2.28630   -4.99937  3.56256   1.000 50.19000  ? 412 ILE   A CA  1 
ATOM   1582 C C   . ILE   A 1 198 ? 3.57232   -5.43247  4.23246   1.000 49.90000  ? 412 ILE   A C   1 
ATOM   1583 O O   . ILE   A 1 198 ? 4.60735   -5.55418  3.56946   1.000 53.99000  ? 412 ILE   A O   1 
ATOM   1584 C CB  . ILE   A 1 198 ? 1.83942   -6.10610  2.58620   1.000 47.86000  ? 412 ILE   A CB  1 
ATOM   1585 C CG1 . ILE   A 1 198 ? 0.52842   -5.78198  1.86326   1.000 48.56000  ? 412 ILE   A CG1 1 
ATOM   1586 C CG2 . ILE   A 1 198 ? 1.67150   -7.39536  3.37579   1.000 47.00000  ? 412 ILE   A CG2 1 
ATOM   1587 C CD1 . ILE   A 1 198 ? 0.68641   -5.16755  0.53246   1.000 51.05000  ? 412 ILE   A CD1 1 
ATOM   1588 N N   . ALA   A 1 199 ? 3.51130   -5.67388  5.52839   1.000 51.27000  ? 413 ALA   A N   1 
ATOM   1589 C CA  . ALA   A 1 199 ? 4.61632   -6.29601  6.24223   1.000 53.41000  ? 413 ALA   A CA  1 
ATOM   1590 C C   . ALA   A 1 199 ? 4.41645   -7.80403  6.22475   1.000 48.78000  ? 413 ALA   A C   1 
ATOM   1591 O O   . ALA   A 1 199 ? 3.33048   -8.29421  6.54656   1.000 51.84000  ? 413 ALA   A O   1 
ATOM   1592 C CB  . ALA   A 1 199 ? 4.71024   -5.78745  7.68239   1.000 52.01000  ? 413 ALA   A CB  1 
ATOM   1593 N N   . PHE   A 1 200 ? 5.45252   -8.53083  5.85156   1.000 44.21000  ? 414 PHE   A N   1 
ATOM   1594 C CA  . PHE   A 1 200 ? 5.39664   -9.97980  5.75710   1.000 46.41000  ? 414 PHE   A CA  1 
ATOM   1595 C C   . PHE   A 1 200 ? 6.23665   -10.58408 6.86994   1.000 49.78000  ? 414 PHE   A C   1 
ATOM   1596 O O   . PHE   A 1 200 ? 7.43862   -10.29202 6.99007   1.000 47.10000  ? 414 PHE   A O   1 
ATOM   1597 C CB  . PHE   A 1 200 ? 5.88072   -10.45433 4.38397   1.000 45.59000  ? 414 PHE   A CB  1 
ATOM   1598 C CG  . PHE   A 1 200 ? 4.91873   -10.13606 3.25204   1.000 50.17000  ? 414 PHE   A CG  1 
ATOM   1599 C CD1 . PHE   A 1 200 ? 3.73279   -10.85511 3.09778   1.000 50.95000  ? 414 PHE   A CD1 1 
ATOM   1600 C CD2 . PHE   A 1 200 ? 5.18967   -9.10976  2.36037   1.000 49.36000  ? 414 PHE   A CD2 1 
ATOM   1601 C CE1 . PHE   A 1 200 ? 2.85780   -10.57185 2.05884   1.000 45.73000  ? 414 PHE   A CE1 1 
ATOM   1602 C CE2 . PHE   A 1 200 ? 4.31268   -8.81251  1.33143   1.000 46.94000  ? 414 PHE   A CE2 1 
ATOM   1603 C CZ  . PHE   A 1 200 ? 3.15374   -9.54655  1.17417   1.000 45.67000  ? 414 PHE   A CZ  1 
ATOM   1604 N N   . VAL   A 1 201 ? 5.59969   -11.40938 7.68667   1.000 49.69000  ? 415 VAL   A N   1 
ATOM   1605 C CA  . VAL   A 1 201 ? 6.30273   -12.20664 8.68044   1.000 48.85000  ? 415 VAL   A CA  1 
ATOM   1606 C C   . VAL   A 1 201 ? 6.00985   -13.65755 8.32698   1.000 51.50000  ? 415 VAL   A C   1 
ATOM   1607 O O   . VAL   A 1 201 ? 4.98790   -13.96344 7.69985   1.000 51.51000  ? 415 VAL   A O   1 
ATOM   1608 C CB  . VAL   A 1 201 ? 5.84465   -11.88212 10.11853  1.000 40.34000  ? 415 VAL   A CB  1 
ATOM   1609 C CG1 . VAL   A 1 201 ? 6.25453   -10.46921 10.49798  1.000 35.24000  ? 415 VAL   A CG1 1 
ATOM   1610 C CG2 . VAL   A 1 201 ? 4.34967   -12.16430 10.28939  1.000 52.00000  ? 415 VAL   A CG2 1 
ATOM   1611 N N   . PHE   A 1 202 ? 6.90491   -14.55860 8.72173   1.000 52.19000  ? 416 PHE   A N   1 
ATOM   1612 C CA  . PHE   A 1 202 ? 6.85104   -15.92645 8.22830   1.000 54.73000  ? 416 PHE   A CA  1 
ATOM   1613 C C   . PHE   A 1 202 ? 7.06408   -16.92079 9.35400   1.000 54.05000  ? 416 PHE   A C   1 
ATOM   1614 O O   . PHE   A 1 202 ? 7.58002   -16.58508 10.41812  1.000 55.35000  ? 416 PHE   A O   1 
ATOM   1615 C CB  . PHE   A 1 202 ? 7.89709   -16.17603 7.12925   1.000 49.21000  ? 416 PHE   A CB  1 
ATOM   1616 C CG  . PHE   A 1 202 ? 7.82205   -15.20668 6.00155   1.000 47.04000  ? 416 PHE   A CG  1 
ATOM   1617 C CD1 . PHE   A 1 202 ? 8.38495   -13.93967 6.11397   1.000 47.64000  ? 416 PHE   A CD1 1 
ATOM   1618 C CD2 . PHE   A 1 202 ? 7.20212   -15.56536 4.81642   1.000 45.68000  ? 416 PHE   A CD2 1 
ATOM   1619 C CE1 . PHE   A 1 202 ? 8.30691   -13.04335 5.06124   1.000 52.70000  ? 416 PHE   A CE1 1 
ATOM   1620 C CE2 . PHE   A 1 202 ? 7.14008   -14.68404 3.76069   1.000 43.37000  ? 416 PHE   A CE2 1 
ATOM   1621 C CZ  . PHE   A 1 202 ? 7.68597   -13.42003 3.88410   1.000 44.32000  ? 416 PHE   A CZ  1 
ATOM   1622 N N   . GLU   A 1 203 ? 6.60719   -18.14174 9.07960   1.000 54.55000  ? 417 GLU   A N   1 
ATOM   1623 C CA  . GLU   A 1 203 ? 6.74825   -19.24202 10.01026  1.000 57.28000  ? 417 GLU   A CA  1 
ATOM   1624 C C   . GLU   A 1 203 ? 6.48738   -20.49378 9.18587   1.000 56.37000  ? 417 GLU   A C   1 
ATOM   1625 O O   . GLU   A 1 203 ? 5.66541   -20.48557 8.29584   1.000 50.37000  ? 417 GLU   A O   1 
ATOM   1626 C CB  . GLU   A 1 203 ? 5.77821   -19.13346 11.17327  1.000 59.69000  ? 417 GLU   A CB  1 
ATOM   1627 C CG  . GLU   A 1 203 ? 5.52829   -20.43470 11.90785  1.000 64.22000  ? 417 GLU   A CG  1 
ATOM   1628 C CD  . GLU   A 1 203 ? 4.60424   -20.27015 13.09188  1.000 66.08000  ? 417 GLU   A CD  1 
ATOM   1629 O OE1 . GLU   A 1 203 ? 4.24314   -19.12428 13.41222  1.000 67.11000  ? 417 GLU   A OE1 1 
ATOM   1630 O OE2 . GLU   A 1 203 ? 4.24130   -21.29037 13.70655  1.000 78.96000  ? 417 GLU   A OE2 1 
ATOM   1631 N N   . VAL   A 1 204 ? 7.23946   -21.54780 9.42856   1.000 64.74000  ? 418 VAL   A N   1 
ATOM   1632 C CA  . VAL   A 1 204 ? 7.05658   -22.80959 8.72116   1.000 65.57000  ? 418 VAL   A CA  1 
ATOM   1633 C C   . VAL   A 1 204 ? 5.80862   -23.51483 9.18090   1.000 63.58000  ? 418 VAL   A C   1 
ATOM   1634 O O   . VAL   A 1 204 ? 5.37057   -23.31322 10.30395  1.000 64.95000  ? 418 VAL   A O   1 
ATOM   1635 C CB  . VAL   A 1 204 ? 8.27565   -23.73455 8.89691   1.000 66.18000  ? 418 VAL   A CB  1 
ATOM   1636 C CG1 . VAL   A 1 204 ? 8.23466   -24.43297 10.24269  1.000 62.77000  ? 418 VAL   A CG1 1 
ATOM   1637 C CG2 . VAL   A 1 204 ? 8.33177   -24.75419 7.77260   1.000 60.47000  ? 418 VAL   A CG2 1 
ATOM   1638 N N   . SER   A 1 205 ? 5.24172   -24.36762 8.34162   1.000 64.74000  ? 419 SER   A N   1 
ATOM   1639 C CA  . SER   A 1 205 ? 4.09576   -25.10185 8.80436   1.000 72.23000  ? 419 SER   A CA  1 
ATOM   1640 C C   . SER   A 1 205 ? 4.59084   -26.34503 9.49199   1.000 77.11000  ? 419 SER   A C   1 
ATOM   1641 O O   . SER   A 1 205 ? 5.11393   -27.24579 8.85672   1.000 78.66000  ? 419 SER   A O   1 
ATOM   1642 C CB  . SER   A 1 205 ? 3.21983   -25.47756 7.62021   1.000 72.90000  ? 419 SER   A CB  1 
ATOM   1643 O OG  . SER   A 1 205 ? 3.89493   -26.34223 6.72896   1.000 77.61000  ? 419 SER   A OG  1 
ATOM   1644 N N   . THR   A 1 206 ? 4.41380   -26.39245 10.80897  1.000 79.00000  ? 420 THR   A N   1 
ATOM   1645 C CA  . THR   A 1 206 ? 4.91487   -27.50966 11.60163  1.000 83.94000  ? 420 THR   A CA  1 
ATOM   1646 C C   . THR   A 1 206 ? 4.24998   -28.78160 11.24322  1.000 88.65000  ? 420 THR   A C   1 
ATOM   1647 O O   . THR   A 1 206 ? 4.88407   -29.82451 11.11791  1.000 94.04000  ? 420 THR   A O   1 
ATOM   1648 C CB  . THR   A 1 206 ? 4.65880   -27.26214 13.08870  1.000 83.35000  ? 420 THR   A CB  1 
ATOM   1649 O OG1 . THR   A 1 206 ? 5.06868   -25.93321 13.42613  1.000 86.13000  ? 420 THR   A OG1 1 
ATOM   1650 C CG2 . THR   A 1 206 ? 5.43986   -28.25634 13.93042  1.000 82.32000  ? 420 THR   A CG2 1 
ATOM   1651 N N   . SER   A 1 207 ? 2.95598   -28.69065 11.04820  1.000 84.83000  ? 421 SER   A N   1 
ATOM   1652 C CA  . SER   A 1 207 ? 2.20809   -29.83759 10.67982  1.000 90.28000  ? 421 SER   A CA  1 
ATOM   1653 C C   . SER   A 1 207 ? 1.86908   -29.31821 9.36298   1.000 90.70000  ? 421 SER   A C   1 
ATOM   1654 O O   . SER   A 1 207 ? 1.36700   -28.20721 9.24031   1.000 93.03000  ? 421 SER   A O   1 
ATOM   1655 C CB  . SER   A 1 207 ? 0.98407   -29.97396 11.55374  1.000 91.15000  ? 421 SER   A CB  1 
ATOM   1656 O OG  . SER   A 1 207 ? 1.34703   -29.99136 12.92275  1.000 90.96000  ? 421 SER   A OG  1 
ATOM   1657 N N   . GLU   A 1 208 ? 2.08918   -30.11187 8.34773   1.000 92.94000  ? 422 GLU   A N   1 
ATOM   1658 C CA  . GLU   A 1 208 ? 1.92418   -29.54548 7.04591   1.000 93.95000  ? 422 GLU   A CA  1 
ATOM   1659 C C   . GLU   A 1 208 ? 0.58922   -29.85641 6.45277   1.000 92.20000  ? 422 GLU   A C   1 
ATOM   1660 O O   . GLU   A 1 208 ? 0.17832   -31.00841 6.35840   1.000 92.93000  ? 422 GLU   A O   1 
ATOM   1661 C CB  . GLU   A 1 208 ? 3.06624   -30.03211 6.15579   1.000 93.93000  ? 422 GLU   A CB  1 
ATOM   1662 C CG  . GLU   A 1 208 ? 3.48135   -31.45418 6.46636   1.000 93.36000  ? 422 GLU   A CG  1 
ATOM   1663 C CD  . GLU   A 1 208 ? 2.63845   -32.46001 5.72702   1.000 95.37000  ? 422 GLU   A CD  1 
ATOM   1664 O OE1 . GLU   A 1 208 ? 2.51448   -32.32364 4.49206   1.000 93.81000  ? 422 GLU   A OE1 1 
ATOM   1665 O OE2 . GLU   A 1 208 ? 2.09951   -33.37826 6.37772   1.000 101.43000 ? 422 GLU   A OE2 1 
ATOM   1666 N N   . HIS   A 1 209 ? -0.09685  -28.80034 6.06707   1.000 89.97000  ? 423 HIS   A N   1 
ATOM   1667 C CA  . HIS   A 1 209 ? -1.38282  -28.93126 5.46099   1.000 84.26000  ? 423 HIS   A CA  1 
ATOM   1668 C C   . HIS   A 1 209 ? -1.16685  -28.10286 4.23626   1.000 81.14000  ? 423 HIS   A C   1 
ATOM   1669 O O   . HIS   A 1 209 ? -2.09085  -27.84470 3.47431   1.000 70.57000  ? 423 HIS   A O   1 
ATOM   1670 C CB  . HIS   A 1 209 ? -2.38690  -28.31663 6.39615   1.000 84.61000  ? 423 HIS   A CB  1 
ATOM   1671 C CG  . HIS   A 1 209 ? -2.07593  -28.56505 7.83509   1.000 90.34000  ? 423 HIS   A CG  1 
ATOM   1672 N ND1 . HIS   A 1 209 ? -2.14784  -29.81823 8.40269   1.000 88.96000  ? 423 HIS   A ND1 1 
ATOM   1673 C CD2 . HIS   A 1 209 ? -1.66303  -27.72932 8.81536   1.000 91.44000  ? 423 HIS   A CD2 1 
ATOM   1674 C CE1 . HIS   A 1 209 ? -1.80489  -29.74060 9.67473   1.000 90.78000  ? 423 HIS   A CE1 1 
ATOM   1675 N NE2 . HIS   A 1 209 ? -1.50500  -28.48466 9.95013   1.000 93.56000  ? 423 HIS   A NE2 1 
ATOM   1676 N N   . GLY   A 1 210 ? 0.07612   -27.68070 4.04043   1.000 84.86000  ? 424 GLY   A N   1 
ATOM   1677 C CA  . GLY   A 1 210 ? 0.43009   -26.85832 2.91170   1.000 71.73000  ? 424 GLY   A CA  1 
ATOM   1678 C C   . GLY   A 1 210 ? 0.36296   -25.42246 3.34914   1.000 72.71000  ? 424 GLY   A C   1 
ATOM   1679 O O   . GLY   A 1 210 ? 0.19590   -25.14684 4.52822   1.000 75.16000  ? 424 GLY   A O   1 
ATOM   1680 N N   . ALA   A 1 211 ? 0.52391   -24.49816 2.42143   1.000 63.42000  ? 425 ALA   A N   1 
ATOM   1681 C CA  . ALA   A 1 211 ? 0.58879   -23.09026 2.78687   1.000 66.17000  ? 425 ALA   A CA  1 
ATOM   1682 C C   . ALA   A 1 211 ? -0.63128  -22.47857 3.45203   1.000 68.72000  ? 425 ALA   A C   1 
ATOM   1683 O O   . ALA   A 1 211 ? -1.75925  -22.78655 3.09589   1.000 70.94000  ? 425 ALA   A O   1 
ATOM   1684 C CB  . ALA   A 1 211 ? 0.98476   -22.26385 1.57214   1.000 61.99000  ? 425 ALA   A CB  1 
ATOM   1685 N N   . GLN   A 1 212 ? -0.39538  -21.60185 4.40931   1.000 68.09000  ? 426 GLN   A N   1 
ATOM   1686 C CA  . GLN   A 1 212 ? -1.44246  -20.91917 5.15549   1.000 63.98000  ? 426 GLN   A CA  1 
ATOM   1687 C C   . GLN   A 1 212 ? -1.05558  -19.45417 5.28495   1.000 57.17000  ? 426 GLN   A C   1 
ATOM   1688 O O   . GLN   A 1 212 ? 0.11439   -19.09803 5.13810   1.000 61.28000  ? 426 GLN   A O   1 
ATOM   1689 C CB  . GLN   A 1 212 ? -1.61146  -21.52162 6.56429   1.000 68.48000  ? 426 GLN   A CB  1 
ATOM   1690 C CG  . GLN   A 1 212 ? -1.83534  -23.02265 6.59682   1.000 72.67000  ? 426 GLN   A CG  1 
ATOM   1691 C CD  . GLN   A 1 212 ? -3.29131  -23.38582 6.78166   1.000 81.62000  ? 426 GLN   A CD  1 
ATOM   1692 O OE1 . GLN   A 1 212 ? -4.16033  -22.90666 6.04878   1.000 84.92000  ? 426 GLN   A OE1 1 
ATOM   1693 N NE2 . GLN   A 1 212 ? -3.56827  -24.24415 7.76438   1.000 81.03000  ? 426 GLN   A NE2 1 
ATOM   1694 N N   . HIS   A 1 213 ? -2.02366  -18.60335 5.61019   1.000 52.21000  ? 427 HIS   A N   1 
ATOM   1695 C CA  . HIS   A 1 213 ? -1.68878  -17.21341 5.88263   1.000 51.22000  ? 427 HIS   A CA  1 
ATOM   1696 C C   . HIS   A 1 213 ? -2.78386  -16.56976 6.71680   1.000 55.54000  ? 427 HIS   A C   1 
ATOM   1697 O O   . HIS   A 1 213 ? -3.90082  -17.07988 6.81160   1.000 62.70000  ? 427 HIS   A O   1 
ATOM   1698 C CB  . HIS   A 1 213 ? -1.48581  -16.43099 4.58688   1.000 49.77000  ? 427 HIS   A CB  1 
ATOM   1699 C CG  . HIS   A 1 213 ? -2.76782  -16.02789 3.93897   1.000 52.61000  ? 427 HIS   A CG  1 
ATOM   1700 N ND1 . HIS   A 1 213 ? -3.59673  -16.93377 3.31466   1.000 55.79000  ? 427 HIS   A ND1 1 
ATOM   1701 C CD2 . HIS   A 1 213 ? -3.38591  -14.82592 3.84932   1.000 51.78000  ? 427 HIS   A CD2 1 
ATOM   1702 C CE1 . HIS   A 1 213 ? -4.66176  -16.30371 2.85082   1.000 62.13000  ? 427 HIS   A CE1 1 
ATOM   1703 N NE2 . HIS   A 1 213 ? -4.55788  -15.02280 3.16122   1.000 61.22000  ? 427 HIS   A NE2 1 
ATOM   1704 N N   . HIS   A 1 214 ? -2.46297  -15.40291 7.27417   1.000 53.03000  ? 428 HIS   A N   1 
ATOM   1705 C CA  . HIS   A 1 214 ? -3.37206  -14.65425 8.13138   1.000 56.59000  ? 428 HIS   A CA  1 
ATOM   1706 C C   . HIS   A 1 214 ? -3.11518  -13.16518 7.96885   1.000 55.61000  ? 428 HIS   A C   1 
ATOM   1707 O O   . HIS   A 1 214 ? -1.95721  -12.73807 7.92402   1.000 56.83000  ? 428 HIS   A O   1 
ATOM   1708 C CB  . HIS   A 1 214 ? -3.19807  -15.05569 9.61126   1.000 62.87000  ? 428 HIS   A CB  1 
ATOM   1709 C CG  . HIS   A 1 214 ? -4.48010  -15.04904 10.38022  1.000 68.10000  ? 428 HIS   A CG  1 
ATOM   1710 N ND1 . HIS   A 1 214 ? -4.83621  -14.02333 11.23053  1.000 70.23000  ? 428 HIS   A ND1 1 
ATOM   1711 C CD2 . HIS   A 1 214 ? -5.51703  -15.92212 10.38291  1.000 66.71000  ? 428 HIS   A CD2 1 
ATOM   1712 C CE1 . HIS   A 1 214 ? -6.02420  -14.27959 11.74841  1.000 71.40000  ? 428 HIS   A CE1 1 
ATOM   1713 N NE2 . HIS   A 1 214 ? -6.46210  -15.42047 11.24304  1.000 77.37000  ? 428 HIS   A NE2 1 
ATOM   1714 N N   . VAL   A 1 215 ? -4.18424  -12.36824 7.89106   1.000 57.73000  ? 429 VAL   A N   1 
ATOM   1715 C CA  . VAL   A 1 215 ? -4.04734  -10.93715 7.63551   1.000 54.10000  ? 429 VAL   A CA  1 
ATOM   1716 C C   . VAL   A 1 215 ? -4.37945  -10.16557 8.90874   1.000 56.50000  ? 429 VAL   A C   1 
ATOM   1717 O O   . VAL   A 1 215 ? -5.13844  -10.63190 9.76257   1.000 60.75000  ? 429 VAL   A O   1 
ATOM   1718 C CB  . VAL   A 1 215 ? -4.92634  -10.49585 6.44762   1.000 47.52000  ? 429 VAL   A CB  1 
ATOM   1719 C CG1 . VAL   A 1 215 ? -4.72545  -9.01373  6.12309   1.000 49.96000  ? 429 VAL   A CG1 1 
ATOM   1720 C CG2 . VAL   A 1 215 ? -4.60124  -11.35245 5.23937   1.000 51.28000  ? 429 VAL   A CG2 1 
ATOM   1721 N N   . TYR   A 1 216 ? -3.75755  -8.99456  9.05113   1.000 54.02000  ? 430 TYR   A N   1 
ATOM   1722 C CA  . TYR   A 1 216 ? -3.90665  -8.13694  10.21639  1.000 53.85000  ? 430 TYR   A CA  1 
ATOM   1723 C C   . TYR   A 1 216 ? -3.80075  -6.68879  9.75784   1.000 52.39000  ? 430 TYR   A C   1 
ATOM   1724 O O   . TYR   A 1 216 ? -3.03875  -6.37444  8.84596   1.000 57.52000  ? 430 TYR   A O   1 
ATOM   1725 C CB  . TYR   A 1 216 ? -2.83566  -8.42319  11.28633  1.000 53.23000  ? 430 TYR   A CB  1 
ATOM   1726 C CG  . TYR   A 1 216 ? -2.82756  -9.83536  11.83889  1.000 56.90000  ? 430 TYR   A CG  1 
ATOM   1727 C CD1 . TYR   A 1 216 ? -2.05747  -10.83211 11.24961  1.000 54.02000  ? 430 TYR   A CD1 1 
ATOM   1728 C CD2 . TYR   A 1 216 ? -3.59257  -10.16977 12.96377  1.000 63.80000  ? 430 TYR   A CD2 1 
ATOM   1729 C CE1 . TYR   A 1 216 ? -2.03838  -12.12627 11.75420  1.000 58.51000  ? 430 TYR   A CE1 1 
ATOM   1730 C CE2 . TYR   A 1 216 ? -3.59048  -11.46693 13.47936  1.000 66.62000  ? 430 TYR   A CE2 1 
ATOM   1731 C CZ  . TYR   A 1 216 ? -2.80539  -12.44468 12.86808  1.000 69.13000  ? 430 TYR   A CZ  1 
ATOM   1732 O OH  . TYR   A 1 216 ? -2.78730  -13.74183 13.35568  1.000 66.37000  ? 430 TYR   A OH  1 
ATOM   1733 N N   . LYS   A 1 217 ? -4.55384  -5.80805  10.40009  1.000 57.15000  ? 431 LYS   A N   1 
ATOM   1734 C CA  . LYS   A 1 217 ? -4.52295  -4.38795  10.07854  1.000 58.85000  ? 431 LYS   A CA  1 
ATOM   1735 C C   . LYS   A 1 217 ? -3.56304  -3.69217  11.03978  1.000 61.34000  ? 431 LYS   A C   1 
ATOM   1736 O O   . LYS   A 1 217 ? -3.69506  -3.82056  12.26274  1.000 62.45000  ? 431 LYS   A O   1 
ATOM   1737 C CB  . LYS   A 1 217 ? -5.92300  -3.77609  10.16668  1.000 61.95000  ? 431 LYS   A CB  1 
ATOM   1738 C CG  . LYS   A 1 217 ? -5.96611  -2.28799  9.85014   1.000 68.19000  ? 431 LYS   A CG  1 
ATOM   1739 C CD  . LYS   A 1 217 ? -5.76508  -2.06351  8.35322   1.000 66.63000  ? 431 LYS   A CD  1 
ATOM   1740 C CE  . LYS   A 1 217 ? -5.59419  -0.58639  8.01169   1.000 67.05000  ? 431 LYS   A CE  1 
ATOM   1741 N NZ  . LYS   A 1 217 ? -4.30125  -0.03544  8.52490   1.000 64.00000  ? 431 LYS   A NZ  1 
ATOM   1742 N N   . LEU   A 1 218 ? -2.59108  -2.96892  10.49704  1.000 60.59000  ? 432 LEU   A N   1 
ATOM   1743 C CA  . LEU   A 1 218 ? -1.63016  -2.25710  11.33229  1.000 62.02000  ? 432 LEU   A CA  1 
ATOM   1744 C C   . LEU   A 1 218 ? -2.18728  -0.90128  11.77169  1.000 59.16000  ? 432 LEU   A C   1 
ATOM   1745 O O   . LEU   A 1 218 ? -2.55732  -0.06906  10.93994  1.000 58.71000  ? 432 LEU   A O   1 
ATOM   1746 C CB  . LEU   A 1 218 ? -0.30315  -2.08276  10.58339  1.000 60.72000  ? 432 LEU   A CB  1 
ATOM   1747 C CG  . LEU   A 1 218 ? 0.60195   -3.28961  10.32004  1.000 55.78000  ? 432 LEU   A CG  1 
ATOM   1748 C CD1 . LEU   A 1 218 ? 1.83994   -2.82728  9.58022   1.000 59.81000  ? 432 LEU   A CD1 1 
ATOM   1749 C CD2 . LEU   A 1 218 ? 1.02897   -3.98097  11.60184  1.000 51.58000  ? 432 LEU   A CD2 1 
ATOM   1750 N N   . VAL   A 1 219 ? -2.20534  -0.67069  13.08377  1.000 61.08000  ? 433 VAL   A N   1 
ATOM   1751 C CA  . VAL   A 1 219 ? -2.83646  0.49707   13.68711  1.000 65.04000  ? 433 VAL   A CA  1 
ATOM   1752 C C   . VAL   A 1 219 ? -1.80654  1.22188   14.54237  1.000 63.31000  ? 433 VAL   A C   1 
ATOM   1753 O O   . VAL   A 1 219 ? -0.82051  0.62483   14.98021  1.000 66.69000  ? 433 VAL   A O   1 
ATOM   1754 C CB  . VAL   A 1 219 ? -4.07645  0.09570   14.53195  1.000 65.20000  ? 433 VAL   A CB  1 
ATOM   1755 C CG1 . VAL   A 1 219 ? -5.17638  -0.42510  13.63075  1.000 64.09000  ? 433 VAL   A CG1 1 
ATOM   1756 C CG2 . VAL   A 1 219 ? -3.71940  -0.95459  15.57963  1.000 55.95000  ? 433 VAL   A CG2 1 
ATOM   1757 N N   . LYS   A 1 220 ? -2.03965  2.51679   14.79276  1.000 68.04000  ? 434 LYS   A N   1 
ATOM   1758 C CA  . LYS   A 1 220 ? -1.14975  3.33860   15.61105  1.000 69.81000  ? 434 LYS   A CA  1 
ATOM   1759 C C   . LYS   A 1 220 ? -1.82183  3.92617   16.84821  1.000 73.46000  ? 434 LYS   A C   1 
ATOM   1760 O O   . LYS   A 1 220 ? -1.26192  4.84302   17.45951  1.000 81.63000  ? 434 LYS   A O   1 
ATOM   1761 C CB  . LYS   A 1 220 ? -0.55081  4.48191   14.78342  1.000 68.78000  ? 434 LYS   A CB  1 
ATOM   1762 C CG  . LYS   A 1 220 ? 0.85914   4.93889   15.22061  1.000 61.35000  ? 434 LYS   A CG  1 
ATOM   1763 C CD  . LYS   A 1 220 ? 1.36007   6.08720   14.35798  1.000 60.55000  ? 434 LYS   A CD  1 
ATOM   1764 C CE  . LYS   A 1 220 ? 2.72602   6.58317   14.79118  1.000 68.52000  ? 434 LYS   A CE  1 
ATOM   1765 N NZ  . LYS   A 1 220 ? 3.18195   7.77645   14.01656  1.000 66.32000  ? 434 LYS   A NZ  1 
ATOM   1766 N N   . ASP   A 1 221 ? -2.98180  3.41095   17.24901  1.000 73.72000  ? 435 ASP   A N   1 
ATOM   1767 C CA  . ASP   A 1 221 ? -3.75488  3.94453   18.39415  1.000 84.10000  ? 435 ASP   A CA  1 
ATOM   1768 C C   . ASP   A 1 221 ? -2.92697  4.57324   19.52738  1.000 80.87000  ? 435 ASP   A C   1 
ATOM   1769 O O   . ASP   A 1 221 ? -2.78795  3.98892   20.60320  1.000 78.51000  ? 435 ASP   A O   1 
ATOM   1770 C CB  . ASP   A 1 221 ? -4.62081  2.84526   19.02078  1.000 75.65000  ? 435 ASP   A CB  1 
ATOM   1771 C CG  . ASP   A 1 221 ? -5.41772  2.07252   17.99452  1.000 84.31000  ? 435 ASP   A CG  1 
ATOM   1772 O OD1 . ASP   A 1 221 ? -5.66073  2.61684   16.88668  1.000 86.96000  ? 435 ASP   A OD1 1 
ATOM   1773 O OD2 . ASP   A 1 221 ? -5.76363  0.90340   18.28714  1.000 79.14000  ? 435 ASP   A OD2 1 
ATOM   1774 N N   . SER   B 1 1   ? 12.57961  -27.08774 -42.29444 1.000 49.52000  ? 215 SER   B N   1 
ATOM   1775 C CA  . SER   B 1 1   ? 13.04793  -26.31379 -41.10554 1.000 51.28000  ? 215 SER   B CA  1 
ATOM   1776 C C   . SER   B 1 1   ? 13.97979  -25.11072 -41.33875 1.000 51.59000  ? 215 SER   B C   1 
ATOM   1777 O O   . SER   B 1 1   ? 15.08365  -25.28662 -41.83810 1.000 45.68000  ? 215 SER   B O   1 
ATOM   1778 C CB  . SER   B 1 1   ? 13.79328  -27.19280 -40.12482 1.000 52.87000  ? 215 SER   B CB  1 
ATOM   1779 O OG  . SER   B 1 1   ? 14.41552  -26.33282 -39.16196 1.000 49.79000  ? 215 SER   B OG  1 
ATOM   1780 N N   . GLN   B 1 2   ? 13.58786  -23.91077 -40.87857 1.000 48.47000  ? 216 GLN   B N   1 
ATOM   1781 C CA  . GLN   B 1 2   ? 14.23564  -22.69270 -41.37669 1.000 45.05000  ? 216 GLN   B CA  1 
ATOM   1782 C C   . GLN   B 1 2   ? 13.98186  -21.52977 -40.41655 1.000 50.05000  ? 216 GLN   B C   1 
ATOM   1783 O O   . GLN   B 1 2   ? 13.21772  -20.59380 -40.68626 1.000 47.80000  ? 216 GLN   B O   1 
ATOM   1784 C CB  . GLN   B 1 2   ? 13.74119  -22.35965 -42.78652 1.000 47.24000  ? 216 GLN   B CB  1 
ATOM   1785 C CG  . GLN   B 1 2   ? 14.24993  -21.05558 -43.38460 1.000 42.85000  ? 216 GLN   B CG  1 
ATOM   1786 C CD  . GLN   B 1 2   ? 13.67350  -20.82154 -44.76041 1.000 45.63000  ? 216 GLN   B CD  1 
ATOM   1787 O OE1 . GLN   B 1 2   ? 14.03625  -21.50546 -45.70656 1.000 47.61000  ? 216 GLN   B OE1 1 
ATOM   1788 N NE2 . GLN   B 1 2   ? 12.73241  -19.89259 -44.86907 1.000 46.03000  ? 216 GLN   B NE2 1 
ATOM   1789 N N   . ASP   B 1 3   ? 14.65721  -21.57180 -39.27476 1.000 52.40000  ? 217 ASP   B N   1 
ATOM   1790 C CA  . ASP   B 1 3   ? 14.46247  -20.58387 -38.22264 1.000 51.73000  ? 217 ASP   B CA  1 
ATOM   1791 C C   . ASP   B 1 3   ? 15.36632  -19.38480 -38.47684 1.000 51.07000  ? 217 ASP   B C   1 
ATOM   1792 O O   . ASP   B 1 3   ? 16.52121  -19.54171 -38.88320 1.000 60.25000  ? 217 ASP   B O   1 
ATOM   1793 C CB  . ASP   B 1 3   ? 14.72792  -21.22593 -36.86076 1.000 52.01000  ? 217 ASP   B CB  1 
ATOM   1794 C CG  . ASP   B 1 3   ? 13.96605  -22.54599 -36.69260 1.000 52.81000  ? 217 ASP   B CG  1 
ATOM   1795 O OD1 . ASP   B 1 3   ? 13.04582  -22.79299 -37.50434 1.000 48.73000  ? 217 ASP   B OD1 1 
ATOM   1796 O OD2 . ASP   B 1 3   ? 14.30437  -23.34802 -35.78575 1.000 49.63000  ? 217 ASP   B OD2 1 
ATOM   1797 N N   . ARG   B 1 4   ? 14.82832  -18.19085 -38.25161 1.000 49.38000  ? 218 ARG   B N   1 
ATOM   1798 C CA  . ARG   B 1 4   ? 15.49215  -16.94379 -38.59074 1.000 49.13000  ? 218 ARG   B CA  1 
ATOM   1799 C C   . ARG   B 1 4   ? 14.91034  -15.82587 -37.73650 1.000 52.15000  ? 218 ARG   B C   1 
ATOM   1800 O O   . ARG   B 1 4   ? 13.73245  -15.85096 -37.37414 1.000 49.68000  ? 218 ARG   B O   1 
ATOM   1801 C CB  . ARG   B 1 4   ? 15.32968  -16.62871 -40.07967 1.000 52.70000  ? 218 ARG   B CB  1 
ATOM   1802 C CG  . ARG   B 1 4   ? 16.62145  -16.65659 -40.83507 1.000 55.80000  ? 218 ARG   B CG  1 
ATOM   1803 C CD  . ARG   B 1 4   ? 16.90631  -17.94854 -41.53123 1.000 53.09000  ? 218 ARG   B CD  1 
ATOM   1804 N NE  . ARG   B 1 4   ? 18.23113  -17.87242 -42.12763 1.000 59.47000  ? 218 ARG   B NE  1 
ATOM   1805 C CZ  . ARG   B 1 4   ? 18.92306  -18.91636 -42.55590 1.000 68.56000  ? 218 ARG   B CZ  1 
ATOM   1806 N NH1 . ARG   B 1 4   ? 18.41914  -20.14139 -42.51382 1.000 70.62000  ? 218 ARG   B NH1 1 
ATOM   1807 N NH2 . ARG   B 1 4   ? 20.13989  -18.72526 -43.06526 1.000 59.25000  ? 218 ARG   B NH2 1 
ATOM   1808 N N   . THR   B 1 5   ? 15.73639  -14.84284 -37.40169 1.000 56.90000  ? 219 THR   B N   1 
ATOM   1809 C CA  . THR   B 1 5   ? 15.26260  -13.81692 -36.48849 1.000 56.58000  ? 219 THR   B CA  1 
ATOM   1810 C C   . THR   B 1 5   ? 14.30732  -12.88494 -37.22515 1.000 53.11000  ? 219 THR   B C   1 
ATOM   1811 O O   . THR   B 1 5   ? 14.49295  -12.58586 -38.41319 1.000 53.72000  ? 219 THR   B O   1 
ATOM   1812 C CB  . THR   B 1 5   ? 16.44175  -13.04489 -35.85580 1.000 61.30000  ? 219 THR   B CB  1 
ATOM   1813 O OG1 . THR   B 1 5   ? 16.99742  -12.10081 -36.77792 1.000 58.57000  ? 219 THR   B OG1 1 
ATOM   1814 C CG2 . THR   B 1 5   ? 17.54093  -14.00685 -35.46119 1.000 59.09000  ? 219 THR   B CG2 1 
ATOM   1815 N N   . ILE   B 1 6   ? 13.26752  -12.45704 -36.50981 1.000 47.37000  ? 220 ILE   B N   1 
ATOM   1816 C CA  . ILE   B 1 6   ? 12.24032  -11.54707 -36.99844 1.000 45.81000  ? 220 ILE   B CA  1 
ATOM   1817 C C   . ILE   B 1 6   ? 12.40747  -10.23010 -36.24542 1.000 48.81000  ? 220 ILE   B C   1 
ATOM   1818 O O   . ILE   B 1 6   ? 12.12483  -10.14519 -35.04233 1.000 49.71000  ? 220 ILE   B O   1 
ATOM   1819 C CB  . ILE   B 1 6   ? 10.82741  -12.11916 -36.79905 1.000 52.27000  ? 220 ILE   B CB  1 
ATOM   1820 C CG1 . ILE   B 1 6   ? 10.62422  -13.37813 -37.65106 1.000 49.66000  ? 220 ILE   B CG1 1 
ATOM   1821 C CG2 . ILE   B 1 6   ? 9.74325   -11.04721 -37.10265 1.000 48.35000  ? 220 ILE   B CG2 1 
ATOM   1822 C CD1 . ILE   B 1 6   ? 9.52244   -14.28822 -37.12677 1.000 48.86000  ? 220 ILE   B CD1 1 
ATOM   1823 N N   . ALA   B 1 7   ? 12.84019  -9.19704  -36.95949 1.000 51.27000  ? 221 ALA   B N   1 
ATOM   1824 C CA  . ALA   B 1 7   ? 13.11930  -7.89706  -36.36450 1.000 49.15000  ? 221 ALA   B CA  1 
ATOM   1825 C C   . ALA   B 1 7   ? 13.04790  -6.83900  -37.45942 1.000 46.47000  ? 221 ALA   B C   1 
ATOM   1826 O O   . ALA   B 1 7   ? 13.46857  -7.07891  -38.58856 1.000 39.52000  ? 221 ALA   B O   1 
ATOM   1827 C CB  . ALA   B 1 7   ? 14.49750  -7.89101  -35.68692 1.000 46.70000  ? 221 ALA   B CB  1 
ATOM   1828 N N   . SER   B 1 8   ? 12.48694  -5.69405  -37.12918 1.000 47.68000  ? 222 SER   B N   1 
ATOM   1829 C CA  . SER   B 1 8   ? 12.55361  -4.53199  -37.98913 1.000 41.36000  ? 222 SER   B CA  1 
ATOM   1830 C C   . SER   B 1 8   ? 13.63472  -3.60296  -37.44841 1.000 45.46000  ? 222 SER   B C   1 
ATOM   1831 O O   . SER   B 1 8   ? 14.45999  -3.98996  -36.61368 1.000 48.85000  ? 222 SER   B O   1 
ATOM   1832 C CB  . SER   B 1 8   ? 11.19755  -3.84007  -38.05568 1.000 44.51000  ? 222 SER   B CB  1 
ATOM   1833 O OG  . SER   B 1 8   ? 10.86690  -3.28016  -36.78355 1.000 48.12000  ? 222 SER   B OG  1 
ATOM   1834 N N   . SER   B 1 9   ? 13.62451  -2.35094  -37.89833 1.000 48.50000  ? 223 SER   B N   1 
ATOM   1835 C CA  . SER   B 1 9   ? 14.52363  -1.37992  -37.29355 1.000 51.54000  ? 223 SER   B CA  1 
ATOM   1836 C C   . SER   B 1 9   ? 13.99401  -0.90503  -35.95236 1.000 51.63000  ? 223 SER   B C   1 
ATOM   1837 O O   . SER   B 1 9   ? 14.68918  -0.16403  -35.25253 1.000 56.23000  ? 223 SER   B O   1 
ATOM   1838 C CB  . SER   B 1 9   ? 14.72129  -0.16786  -38.20854 1.000 52.07000  ? 223 SER   B CB  1 
ATOM   1839 O OG  . SER   B 1 9   ? 13.48916  0.46409   -38.48913 1.000 59.30000  ? 223 SER   B OG  1 
ATOM   1840 N N   . ARG   B 1 10  ? 12.76514  -1.28712  -35.59501 1.000 47.52000  ? 224 ARG   B N   1 
ATOM   1841 C CA  . ARG   B 1 10  ? 12.12647  -0.74323  -34.41378 1.000 52.73000  ? 224 ARG   B CA  1 
ATOM   1842 C C   . ARG   B 1 10  ? 11.61283  -1.78431  -33.42669 1.000 48.57000  ? 224 ARG   B C   1 
ATOM   1843 O O   . ARG   B 1 10  ? 11.42017  -1.44339  -32.25961 1.000 47.46000  ? 224 ARG   B O   1 
ATOM   1844 C CB  . ARG   B 1 10  ? 10.97429  0.17873   -34.82338 1.000 50.65000  ? 224 ARG   B CB  1 
ATOM   1845 C CG  . ARG   B 1 10  ? 11.35493  1.26581   -35.80643 1.000 51.22000  ? 224 ARG   B CG  1 
ATOM   1846 C CD  . ARG   B 1 10  ? 12.07206  2.44381   -35.16658 1.000 61.05000  ? 224 ARG   B CD  1 
ATOM   1847 N NE  . ARG   B 1 10  ? 11.40039  2.95671   -33.97235 1.000 69.27000  ? 224 ARG   B NE  1 
ATOM   1848 C CZ  . ARG   B 1 10  ? 10.48233  3.91365   -33.97301 1.000 76.00000  ? 224 ARG   B CZ  1 
ATOM   1849 N NH1 . ARG   B 1 10  ? 10.04096  4.44869   -35.10485 1.000 76.31000  ? 224 ARG   B NH1 1 
ATOM   1850 N NH2 . ARG   B 1 10  ? 9.99366   4.34556   -32.80884 1.000 74.72000  ? 224 ARG   B NH2 1 
ATOM   1851 N N   . LEU   B 1 11  ? 11.41378  -3.03330  -33.84370 1.000 49.34000  ? 225 LEU   B N   1 
ATOM   1852 C CA  . LEU   B 1 11  ? 10.88111  -4.06038  -32.95660 1.000 48.31000  ? 225 LEU   B CA  1 
ATOM   1853 C C   . LEU   B 1 11  ? 11.43806  -5.41433  -33.37684 1.000 49.59000  ? 225 LEU   B C   1 
ATOM   1854 O O   . LEU   B 1 11  ? 11.56371  -5.69125  -34.57390 1.000 52.49000  ? 225 LEU   B O   1 
ATOM   1855 C CB  . LEU   B 1 11  ? 9.34410   -4.08447  -33.00013 1.000 46.16000  ? 225 LEU   B CB  1 
ATOM   1856 C CG  . LEU   B 1 11  ? 8.61247   -4.89557  -31.92396 1.000 45.13000  ? 225 LEU   B CG  1 
ATOM   1857 C CD1 . LEU   B 1 11  ? 8.80084   -4.23964  -30.56597 1.000 44.93000  ? 225 LEU   B CD1 1 
ATOM   1858 C CD2 . LEU   B 1 11  ? 7.14739   -5.00264  -32.22152 1.000 41.01000  ? 225 LEU   B CD2 1 
ATOM   1859 N N   . ARG   B 1 12  ? 11.77741  -6.25236  -32.39400 1.000 42.92000  ? 226 ARG   B N   1 
ATOM   1860 C CA  . ARG   B 1 12  ? 12.19341  -7.62932  -32.63720 1.000 49.09000  ? 226 ARG   B CA  1 
ATOM   1861 C C   . ARG   B 1 12  ? 11.23168  -8.58142  -31.93796 1.000 53.31000  ? 226 ARG   B C   1 
ATOM   1862 O O   . ARG   B 1 12  ? 10.84902  -8.35451  -30.78683 1.000 51.10000  ? 226 ARG   B O   1 
ATOM   1863 C CB  . ARG   B 1 12  ? 13.63358  -7.90027  -32.13465 1.000 55.50000  ? 226 ARG   B CB  1 
ATOM   1864 C CG  . ARG   B 1 12  ? 13.98672  -9.40426  -31.97985 1.000 56.48000  ? 226 ARG   B CG  1 
ATOM   1865 C CD  . ARG   B 1 12  ? 15.37391  -9.63121  -31.39728 1.000 56.52000  ? 226 ARG   B CD  1 
ATOM   1866 N NE  . ARG   B 1 12  ? 16.37758  -9.56709  -32.45058 1.000 65.11000  ? 226 ARG   B NE  1 
ATOM   1867 C CZ  . ARG   B 1 12  ? 17.01241  -8.46003  -32.82071 1.000 69.59000  ? 226 ARG   B CZ  1 
ATOM   1868 N NH1 . ARG   B 1 12  ? 16.84053  -7.30908  -32.18059 1.000 63.49000  ? 226 ARG   B NH1 1 
ATOM   1869 N NH2 . ARG   B 1 12  ? 17.82909  -8.50193  -33.86896 1.000 72.11000  ? 226 ARG   B NH2 1 
ATOM   1870 N N   . LEU   B 1 13  ? 10.84754  -9.65640  -32.62091 1.000 50.10000  ? 227 LEU   B N   1 
ATOM   1871 C CA  . LEU   B 1 13  ? 10.03579  -10.68549 -31.98572 1.000 48.18000  ? 227 LEU   B CA  1 
ATOM   1872 C C   . LEU   B 1 13  ? 10.96304  -11.70847 -31.33806 1.000 50.18000  ? 227 LEU   B C   1 
ATOM   1873 O O   . LEU   B 1 13  ? 11.87287  -12.21738 -31.99937 1.000 56.73000  ? 227 LEU   B O   1 
ATOM   1874 C CB  . LEU   B 1 13  ? 9.11052   -11.35848 -32.99548 1.000 49.88000  ? 227 LEU   B CB  1 
ATOM   1875 C CG  . LEU   B 1 13  ? 8.31978   -12.51057 -32.36131 1.000 52.60000  ? 227 LEU   B CG  1 
ATOM   1876 C CD1 . LEU   B 1 13  ? 6.91290   -12.07467 -31.89885 1.000 43.23000  ? 227 LEU   B CD1 1 
ATOM   1877 C CD2 . LEU   B 1 13  ? 8.26557   -13.73352 -33.27336 1.000 52.59000  ? 227 LEU   B CD2 1 
ATOM   1878 N N   . LEU   B 1 14  ? 10.74645  -11.99356 -30.04401 1.000 52.33000  ? 228 LEU   B N   1 
ATOM   1879 C CA  . LEU   B 1 14  ? 11.57173  -12.95655 -29.30832 1.000 55.81000  ? 228 LEU   B CA  1 
ATOM   1880 C C   . LEU   B 1 14  ? 10.90188  -14.30260 -29.09919 1.000 55.52000  ? 228 LEU   B C   1 
ATOM   1881 O O   . LEU   B 1 14  ? 11.58895  -15.33257 -29.06946 1.000 55.45000  ? 228 LEU   B O   1 
ATOM   1882 C CB  . LEU   B 1 14  ? 11.95912  -12.41561 -27.93741 1.000 47.48000  ? 228 LEU   B CB  1 
ATOM   1883 C CG  . LEU   B 1 14  ? 12.42005  -10.97559 -27.89046 1.000 52.16000  ? 228 LEU   B CG  1 
ATOM   1884 C CD1 . LEU   B 1 14  ? 12.34446  -10.45367 -26.44541 1.000 51.92000  ? 228 LEU   B CD1 1 
ATOM   1885 C CD2 . LEU   B 1 14  ? 13.85189  -10.97547 -28.41890 1.000 49.44000  ? 228 LEU   B CD2 1 
ATOM   1886 N N   . GLU   B 1 15  ? 9.58593   -14.31369 -28.92479 1.000 49.15000  ? 229 GLU   B N   1 
ATOM   1887 C CA  . GLU   B 1 15  ? 8.90808   -15.56674 -28.67566 1.000 53.86000  ? 229 GLU   B CA  1 
ATOM   1888 C C   . GLU   B 1 15  ? 7.48092   -15.45880 -29.17822 1.000 54.30000  ? 229 GLU   B C   1 
ATOM   1889 O O   . GLU   B 1 15  ? 6.89486   -14.37583 -29.17198 1.000 53.57000  ? 229 GLU   B O   1 
ATOM   1890 C CB  . GLU   B 1 15  ? 8.98355   -15.92283 -27.18070 1.000 52.85000  ? 229 GLU   B CB  1 
ATOM   1891 C CG  . GLU   B 1 15  ? 8.32575   -17.24689 -26.79958 1.000 60.73000  ? 229 GLU   B CG  1 
ATOM   1892 C CD  . GLU   B 1 15  ? 7.22105   -17.06201 -25.76124 1.000 64.34000  ? 229 GLU   B CD  1 
ATOM   1893 O OE1 . GLU   B 1 15  ? 7.48432   -16.37606 -24.73628 1.000 63.79000  ? 229 GLU   B OE1 1 
ATOM   1894 O OE2 . GLU   B 1 15  ? 6.07900   -17.53606 -26.01292 1.000 56.22000  ? 229 GLU   B OE2 1 
ATOM   1895 N N   . TYR   B 1 16  ? 6.94684   -16.58780 -29.66112 1.000 53.43000  ? 230 TYR   B N   1 
ATOM   1896 C CA  . TYR   B 1 16  ? 5.54173   -16.73586 -30.03071 1.000 50.06000  ? 230 TYR   B CA  1 
ATOM   1897 C C   . TYR   B 1 16  ? 5.10791   -18.16390 -29.73866 1.000 48.80000  ? 230 TYR   B C   1 
ATOM   1898 O O   . TYR   B 1 16  ? 5.73282   -19.10784 -30.21690 1.000 53.05000  ? 230 TYR   B O   1 
ATOM   1899 C CB  . TYR   B 1 16  ? 5.32226   -16.42179 -31.51662 1.000 48.10000  ? 230 TYR   B CB  1 
ATOM   1900 C CG  . TYR   B 1 16  ? 3.87714   -16.18785 -31.89817 1.000 48.70000  ? 230 TYR   B CG  1 
ATOM   1901 C CD1 . TYR   B 1 16  ? 3.25515   -14.97890 -31.61191 1.000 49.90000  ? 230 TYR   B CD1 1 
ATOM   1902 C CD2 . TYR   B 1 16  ? 3.12700   -17.17886 -32.51800 1.000 48.24000  ? 230 TYR   B CD2 1 
ATOM   1903 C CE1 . TYR   B 1 16  ? 1.94803   -14.74196 -31.95050 1.000 44.73000  ? 230 TYR   B CE1 1 
ATOM   1904 C CE2 . TYR   B 1 16  ? 1.79088   -16.95692 -32.87458 1.000 51.23000  ? 230 TYR   B CE2 1 
ATOM   1905 C CZ  . TYR   B 1 16  ? 1.20490   -15.72597 -32.58233 1.000 56.73000  ? 230 TYR   B CZ  1 
ATOM   1906 O OH  . TYR   B 1 16  ? -0.12521  -15.46103 -32.90491 1.000 48.70000  ? 230 TYR   B OH  1 
ATOM   1907 N N   . SER   B 1 17  ? 4.06116   -18.34001 -28.95235 1.000 49.36000  ? 231 SER   B N   1 
ATOM   1908 C CA  . SER   B 1 17  ? 3.52530   -19.68005 -28.74626 1.000 51.55000  ? 231 SER   B CA  1 
ATOM   1909 C C   . SER   B 1 17  ? 2.01329   -19.62314 -28.76580 1.000 44.98000  ? 231 SER   B C   1 
ATOM   1910 O O   . SER   B 1 17  ? 1.42438   -18.67320 -28.26157 1.000 47.59000  ? 231 SER   B O   1 
ATOM   1911 C CB  . SER   B 1 17  ? 3.96374   -20.29611 -27.41543 1.000 46.94000  ? 231 SER   B CB  1 
ATOM   1912 O OG  . SER   B 1 17  ? 5.28281   -19.91405 -27.10081 1.000 60.95000  ? 231 SER   B OG  1 
ATOM   1913 N N   . ALA   B 1 18  ? 1.39717   -20.64214 -29.34567 1.000 40.04000  ? 232 ALA   B N   1 
ATOM   1914 C CA  . ALA   B 1 18  ? -0.01275  -20.93524 -29.13126 1.000 41.04000  ? 232 ALA   B CA  1 
ATOM   1915 C C   . ALA   B 1 18  ? -0.06249  -22.33827 -28.55733 1.000 45.11000  ? 232 ALA   B C   1 
ATOM   1916 O O   . ALA   B 1 18  ? 0.48838   -23.27221 -29.15155 1.000 47.40000  ? 232 ALA   B O   1 
ATOM   1917 C CB  . ALA   B 1 18  ? -0.83214  -20.83821 -30.41901 1.000 40.84000  ? 232 ALA   B CB  1 
ATOM   1918 N N   . PHE   B 1 19  ? -0.69913  -22.48238 -27.39814 1.000 45.29000  ? 233 PHE   B N   1 
ATOM   1919 C CA  . PHE   B 1 19  ? -0.59383  -23.70742 -26.62525 1.000 46.15000  ? 233 PHE   B CA  1 
ATOM   1920 C C   . PHE   B 1 19  ? -1.94362  -24.04453 -26.00685 1.000 48.21000  ? 233 PHE   B C   1 
ATOM   1921 O O   . PHE   B 1 19  ? -2.83364  -23.19359 -25.90953 1.000 45.82000  ? 233 PHE   B O   1 
ATOM   1922 C CB  . PHE   B 1 19  ? 0.47550   -23.56842 -25.53256 1.000 47.07000  ? 233 PHE   B CB  1 
ATOM   1923 C CG  . PHE   B 1 19  ? 0.30568   -22.32848 -24.68244 1.000 47.65000  ? 233 PHE   B CG  1 
ATOM   1924 C CD1 . PHE   B 1 19  ? -0.47797  -22.35359 -23.53820 1.000 45.33000  ? 233 PHE   B CD1 1 
ATOM   1925 C CD2 . PHE   B 1 19  ? 0.93351   -21.14442 -25.03056 1.000 45.30000  ? 233 PHE   B CD2 1 
ATOM   1926 C CE1 . PHE   B 1 19  ? -0.63280  -21.22864 -22.77309 1.000 49.12000  ? 233 PHE   B CE1 1 
ATOM   1927 C CE2 . PHE   B 1 19  ? 0.77467   -20.01347 -24.27345 1.000 44.55000  ? 233 PHE   B CE2 1 
ATOM   1928 C CZ  . PHE   B 1 19  ? -0.00998  -20.05458 -23.14121 1.000 49.51000  ? 233 PHE   B CZ  1 
ATOM   1929 N N   . MET   B 1 20  ? -2.07742  -25.30956 -25.59889 1.000 50.34000  ? 234 MET   B N   1 
ATOM   1930 C CA  . MET   B 1 20  ? -3.19415  -25.80967 -24.80558 1.000 53.64000  ? 234 MET   B CA  1 
ATOM   1931 C C   . MET   B 1 20  ? -2.65372  -26.32472 -23.47677 1.000 57.06000  ? 234 MET   B C   1 
ATOM   1932 O O   . MET   B 1 20  ? -1.75866  -27.17767 -23.46509 1.000 59.82000  ? 234 MET   B O   1 
ATOM   1933 C CB  . MET   B 1 20  ? -3.92531  -26.93667 -25.53742 1.000 55.98000  ? 234 MET   B CB  1 
ATOM   1934 C CG  . MET   B 1 20  ? -5.26009  -27.35179 -24.90604 1.000 64.30000  ? 234 MET   B CG  1 
ATOM   1935 S SD  . MET   B 1 20  ? -5.69111  -29.07279 -25.29401 1.000 81.49000  ? 234 MET   B SD  1 
ATOM   1936 C CE  . MET   B 1 20  ? -4.07003  -29.84470 -25.18454 1.000 65.92000  ? 234 MET   B CE  1 
ATOM   1937 N N   . GLU   B 1 21  ? -3.17841  -25.81681 -22.36058 1.000 52.99000  ? 235 GLU   B N   1 
ATOM   1938 C CA  . GLU   B 1 21  ? -2.61999  -26.12086 -21.04577 1.000 55.32000  ? 235 GLU   B CA  1 
ATOM   1939 C C   . GLU   B 1 21  ? -3.66168  -26.81597 -20.16949 1.000 55.60000  ? 235 GLU   B C   1 
ATOM   1940 O O   . GLU   B 1 21  ? -4.78667  -26.32204 -20.01712 1.000 53.04000  ? 235 GLU   B O   1 
ATOM   1941 C CB  . GLU   B 1 21  ? -2.09586  -24.84086 -20.38785 1.000 52.88000  ? 235 GLU   B CB  1 
ATOM   1942 C CG  . GLU   B 1 21  ? -1.30847  -25.07089 -19.13211 1.000 48.03000  ? 235 GLU   B CG  1 
ATOM   1943 C CD  . GLU   B 1 21  ? -1.49023  -23.94696 -18.12099 1.000 60.06000  ? 235 GLU   B CD  1 
ATOM   1944 O OE1 . GLU   B 1 21  ? -1.33642  -22.76393 -18.53796 1.000 54.90000  ? 235 GLU   B OE1 1 
ATOM   1945 O OE2 . GLU   B 1 21  ? -1.83685  -24.25605 -16.93190 1.000 54.43000  ? 235 GLU   B OE2 1 
ATOM   1946 N N   . VAL   B 1 22  ? -3.28244  -27.95498 -19.58967 1.000 53.55000  ? 236 VAL   B N   1 
ATOM   1947 C CA  . VAL   B 1 22  ? -4.19216  -28.82308 -18.83845 1.000 51.98000  ? 236 VAL   B CA  1 
ATOM   1948 C C   . VAL   B 1 22  ? -3.58973  -29.12212 -17.47265 1.000 53.92000  ? 236 VAL   B C   1 
ATOM   1949 O O   . VAL   B 1 22  ? -2.59366  -29.84707 -17.36899 1.000 52.97000  ? 236 VAL   B O   1 
ATOM   1950 C CB  . VAL   B 1 22  ? -4.47432  -30.12305 -19.59844 1.000 54.46000  ? 236 VAL   B CB  1 
ATOM   1951 C CG1 . VAL   B 1 22  ? -5.17199  -31.12014 -18.71128 1.000 57.24000  ? 236 VAL   B CG1 1 
ATOM   1952 C CG2 . VAL   B 1 22  ? -5.32070  -29.81403 -20.81116 1.000 65.40000  ? 236 VAL   B CG2 1 
ATOM   1953 N N   . GLN   B 1 23  ? -4.19844  -28.57622 -16.42243 1.000 56.09000  ? 237 GLN   B N   1 
ATOM   1954 C CA  . GLN   B 1 23  ? -3.76801  -28.91027 -15.06758 1.000 51.89000  ? 237 GLN   B CA  1 
ATOM   1955 C C   . GLN   B 1 23  ? -4.06484  -30.38430 -14.80058 1.000 51.37000  ? 237 GLN   B C   1 
ATOM   1956 O O   . GLN   B 1 23  ? -5.21785  -30.81436 -14.90025 1.000 56.26000  ? 237 GLN   B O   1 
ATOM   1957 C CB  . GLN   B 1 23  ? -4.45375  -28.00637 -14.04332 1.000 45.69000  ? 237 GLN   B CB  1 
ATOM   1958 C CG  . GLN   B 1 23  ? -3.80334  -28.04641 -12.69052 1.000 52.43000  ? 237 GLN   B CG  1 
ATOM   1959 C CD  . GLN   B 1 23  ? -2.44738  -27.33833 -12.67589 1.000 54.46000  ? 237 GLN   B CD  1 
ATOM   1960 O OE1 . GLN   B 1 23  ? -2.28360  -26.22929 -13.21488 1.000 53.46000  ? 237 GLN   B OE1 1 
ATOM   1961 N NE2 . GLN   B 1 23  ? -1.45816  -27.99831 -12.08923 1.000 49.29000  ? 237 GLN   B NE2 1 
ATOM   1962 N N   . ARG   B 1 24  ? -3.01672  -31.16526 -14.53394 1.000 48.54000  ? 238 ARG   B N   1 
ATOM   1963 C CA  . ARG   B 1 24  ? -3.13160  -32.61427 -14.40999 1.000 51.88000  ? 238 ARG   B CA  1 
ATOM   1964 C C   . ARG   B 1 24  ? -3.36613  -33.06237 -12.97194 1.000 54.92000  ? 238 ARG   B C   1 
ATOM   1965 O O   . ARG   B 1 24  ? -3.98801  -34.10842 -12.75481 1.000 58.49000  ? 238 ARG   B O   1 
ATOM   1966 C CB  . ARG   B 1 24  ? -1.87473  -33.30817 -14.96941 1.000 57.49000  ? 238 ARG   B CB  1 
ATOM   1967 C CG  . ARG   B 1 24  ? -1.95614  -33.83509 -16.43442 1.000 65.76000  ? 238 ARG   B CG  1 
ATOM   1968 C CD  . ARG   B 1 24  ? -2.15506  -35.38610 -16.46145 1.000 71.30000  ? 238 ARG   B CD  1 
ATOM   1969 N NE  . ARG   B 1 24  ? -0.90401  -36.15502 -16.44387 1.000 78.15000  ? 238 ARG   B NE  1 
ATOM   1970 C CZ  . ARG   B 1 24  ? -0.45766  -36.90306 -15.43105 1.000 78.91000  ? 238 ARG   B CZ  1 
ATOM   1971 N NH1 . ARG   B 1 24  ? -1.11230  -36.98816 -14.28285 1.000 74.40000  ? 238 ARG   B NH1 1 
ATOM   1972 N NH2 . ARG   B 1 24  ? 0.68934   -37.56698 -15.56544 1.000 80.56000  ? 238 ARG   B NH2 1 
ATOM   1973 N N   . ASP   B 1 25  ? -2.87188  -32.30040 -11.99105 1.000 53.43000  ? 239 ASP   B N   1 
ATOM   1974 C CA  . ASP   B 1 25  ? -3.12743  -32.46349 -10.55898 1.000 48.27000  ? 239 ASP   B CA  1 
ATOM   1975 C C   . ASP   B 1 25  ? -2.78031  -31.12351 -9.90301  1.000 50.41000  ? 239 ASP   B C   1 
ATOM   1976 O O   . ASP   B 1 25  ? -2.42259  -30.19745 -10.63806 1.000 50.53000  ? 239 ASP   B O   1 
ATOM   1977 C CB  . ASP   B 1 25  ? -2.35319  -33.66648 -9.99629  1.000 49.79000  ? 239 ASP   B CB  1 
ATOM   1978 C CG  . ASP   B 1 25  ? -0.84416  -33.41840 -9.82273  1.000 52.87000  ? 239 ASP   B CG  1 
ATOM   1979 O OD1 . ASP   B 1 25  ? -0.39515  -32.28439 -9.58480  1.000 53.25000  ? 239 ASP   B OD1 1 
ATOM   1980 O OD2 . ASP   B 1 25  ? -0.09210  -34.41336 -9.83102  1.000 56.83000  ? 239 ASP   B OD2 1 
ATOM   1981 N N   . PRO   B 1 26  ? -2.87092  -30.94059 -8.56997  1.000 56.51000  ? 240 PRO   B N   1 
ATOM   1982 C CA  . PRO   B 1 26  ? -2.66584  -29.57961 -8.03295  1.000 54.57000  ? 240 PRO   B CA  1 
ATOM   1983 C C   . PRO   B 1 26  ? -1.27494  -29.01052 -8.27434  1.000 53.14000  ? 240 PRO   B C   1 
ATOM   1984 O O   . PRO   B 1 26  ? -1.10700  -27.78651 -8.24132  1.000 56.68000  ? 240 PRO   B O   1 
ATOM   1985 C CB  . PRO   B 1 26  ? -2.94337  -29.74671 -6.53288  1.000 50.36000  ? 240 PRO   B CB  1 
ATOM   1986 C CG  . PRO   B 1 26  ? -3.77427  -30.91577 -6.43569  1.000 48.83000  ? 240 PRO   B CG  1 
ATOM   1987 C CD  . PRO   B 1 26  ? -3.31254  -31.85268 -7.49489  1.000 49.29000  ? 240 PRO   B CD  1 
ATOM   1988 N N   . ASP   B 1 27  ? -0.27597  -29.85144 -8.53270  1.000 56.31000  ? 241 ASP   B N   1 
ATOM   1989 C CA  . ASP   B 1 27  ? 1.10796   -29.40736 -8.66409  1.000 57.56000  ? 241 ASP   B CA  1 
ATOM   1990 C C   . ASP   B 1 27  ? 1.62053   -29.42024 -10.09825 1.000 55.51000  ? 241 ASP   B C   1 
ATOM   1991 O O   . ASP   B 1 27  ? 2.67141   -28.82517 -10.37453 1.000 58.03000  ? 241 ASP   B O   1 
ATOM   1992 C CB  . ASP   B 1 27  ? 2.02128   -30.30035 -7.80642  1.000 60.81000  ? 241 ASP   B CB  1 
ATOM   1993 C CG  . ASP   B 1 27  ? 1.92571   -29.98344 -6.33037  1.000 70.18000  ? 241 ASP   B CG  1 
ATOM   1994 O OD1 . ASP   B 1 27  ? 2.15875   -28.81145 -5.96538  1.000 71.81000  ? 241 ASP   B OD1 1 
ATOM   1995 O OD2 . ASP   B 1 27  ? 1.59100   -30.89551 -5.54232  1.000 75.79000  ? 241 ASP   B OD2 1 
ATOM   1996 N N   . THR   B 1 28  ? 0.93029   -30.09423 -11.00508 1.000 50.02000  ? 242 THR   B N   1 
ATOM   1997 C CA  . THR   B 1 28  ? 1.50493   -30.47712 -12.28127 1.000 52.63000  ? 242 THR   B CA  1 
ATOM   1998 C C   . THR   B 1 28  ? 0.50257   -30.26512 -13.40496 1.000 53.44000  ? 242 THR   B C   1 
ATOM   1999 O O   . THR   B 1 28  ? -0.63738  -30.73419 -13.32864 1.000 51.32000  ? 242 THR   B O   1 
ATOM   2000 C CB  . THR   B 1 28  ? 1.95602   -31.93310 -12.23749 1.000 56.31000  ? 242 THR   B CB  1 
ATOM   2001 O OG1 . THR   B 1 28  ? 2.80838   -32.13812 -11.09377 1.000 61.47000  ? 242 THR   B OG1 1 
ATOM   2002 C CG2 . THR   B 1 28  ? 2.69566   -32.27898 -13.49774 1.000 54.98000  ? 242 THR   B CG2 1 
ATOM   2003 N N   . TYR   B 1 29  ? 0.93222   -29.54703 -14.43405 1.000 54.95000  ? 243 TYR   B N   1 
ATOM   2004 C CA  . TYR   B 1 29  ? 0.12585   -29.28801 -15.61279 1.000 52.55000  ? 243 TYR   B CA  1 
ATOM   2005 C C   . TYR   B 1 29  ? 0.90449   -29.67889 -16.86504 1.000 51.69000  ? 243 TYR   B C   1 
ATOM   2006 O O   . TYR   B 1 29  ? 2.13449   -29.70182 -16.87842 1.000 48.52000  ? 243 TYR   B O   1 
ATOM   2007 C CB  . TYR   B 1 29  ? -0.29626  -27.81003 -15.68257 1.000 51.95000  ? 243 TYR   B CB  1 
ATOM   2008 C CG  . TYR   B 1 29  ? 0.83461   -26.81095 -15.92586 1.000 53.94000  ? 243 TYR   B CG  1 
ATOM   2009 C CD1 . TYR   B 1 29  ? 1.60290   -26.32897 -14.86506 1.000 53.34000  ? 243 TYR   B CD1 1 
ATOM   2010 C CD2 . TYR   B 1 29  ? 1.13919   -26.35986 -17.21192 1.000 48.83000  ? 243 TYR   B CD2 1 
ATOM   2011 C CE1 . TYR   B 1 29  ? 2.62879   -25.41690 -15.06432 1.000 48.77000  ? 243 TYR   B CE1 1 
ATOM   2012 C CE2 . TYR   B 1 29  ? 2.15707   -25.44379 -17.42618 1.000 51.07000  ? 243 TYR   B CE2 1 
ATOM   2013 C CZ  . TYR   B 1 29  ? 2.90537   -24.98281 -16.34138 1.000 53.72000  ? 243 TYR   B CZ  1 
ATOM   2014 O OH  . TYR   B 1 29  ? 3.92527   -24.08174 -16.50964 1.000 54.04000  ? 243 TYR   B OH  1 
ATOM   2015 N N   . SER   B 1 30  ? 0.16519   -30.00388 -17.91684 1.000 56.39000  ? 244 SER   B N   1 
ATOM   2016 C CA  . SER   B 1 30  ? 0.72580   -30.23477 -19.24102 1.000 56.72000  ? 244 SER   B CA  1 
ATOM   2017 C C   . SER   B 1 30  ? 0.52346   -29.00673 -20.11389 1.000 55.87000  ? 244 SER   B C   1 
ATOM   2018 O O   . SER   B 1 30  ? -0.52156  -28.34879 -20.05053 1.000 55.07000  ? 244 SER   B O   1 
ATOM   2019 C CB  . SER   B 1 30  ? 0.07566   -31.43577 -19.92289 1.000 54.44000  ? 244 SER   B CB  1 
ATOM   2020 O OG  . SER   B 1 30  ? 0.61987   -32.66176 -19.47813 1.000 67.47000  ? 244 SER   B OG  1 
ATOM   2021 N N   . LYS   B 1 31  ? 1.52019   -28.71562 -20.94518 1.000 58.14000  ? 245 LYS   B N   1 
ATOM   2022 C CA  . LYS   B 1 31  ? 1.44684   -27.62757 -21.91109 1.000 55.32000  ? 245 LYS   B CA  1 
ATOM   2023 C C   . LYS   B 1 31  ? 1.88145   -28.15147 -23.26925 1.000 56.08000  ? 245 LYS   B C   1 
ATOM   2024 O O   . LYS   B 1 31  ? 3.05641   -28.47039 -23.46063 1.000 56.75000  ? 245 LYS   B O   1 
ATOM   2025 C CB  . LYS   B 1 31  ? 2.31190   -26.44755 -21.46829 1.000 54.11000  ? 245 LYS   B CB  1 
ATOM   2026 C CG  . LYS   B 1 31  ? 2.02161   -25.16152 -22.19612 1.000 52.53000  ? 245 LYS   B CG  1 
ATOM   2027 C CD  . LYS   B 1 31  ? 2.51577   -23.96254 -21.41120 1.000 53.08000  ? 245 LYS   B CD  1 
ATOM   2028 C CE  . LYS   B 1 31  ? 2.67144   -22.73448 -22.28918 1.000 47.19000  ? 245 LYS   B CE  1 
ATOM   2029 N NZ  . LYS   B 1 31  ? 3.12960   -21.54950 -21.50525 1.000 58.86000  ? 245 LYS   B NZ  1 
ATOM   2030 N N   . HIS   B 1 32  ? 0.92618   -28.26847 -24.19497 1.000 58.72000  ? 246 HIS   B N   1 
ATOM   2031 C CA  . HIS   B 1 32  ? 1.17978   -28.66537 -25.57807 1.000 53.14000  ? 246 HIS   B CA  1 
ATOM   2032 C C   . HIS   B 1 32  ? 1.23445   -27.41732 -26.44301 1.000 50.34000  ? 246 HIS   B C   1 
ATOM   2033 O O   . HIS   B 1 32  ? 0.30540   -26.60138 -26.42469 1.000 48.52000  ? 246 HIS   B O   1 
ATOM   2034 C CB  . HIS   B 1 32  ? 0.09068   -29.60441 -26.09679 1.000 51.59000  ? 246 HIS   B CB  1 
ATOM   2035 C CG  . HIS   B 1 32  ? 0.22026   -29.95032 -27.54885 1.000 55.71000  ? 246 HIS   B CG  1 
ATOM   2036 N ND1 . HIS   B 1 32  ? 0.97618   -31.01425 -27.99414 1.000 66.95000  ? 246 HIS   B ND1 1 
ATOM   2037 C CD2 . HIS   B 1 32  ? -0.32211  -29.38728 -28.65566 1.000 53.76000  ? 246 HIS   B CD2 1 
ATOM   2038 C CE1 . HIS   B 1 32  ? 0.89779   -31.08817 -29.31112 1.000 61.71000  ? 246 HIS   B CE1 1 
ATOM   2039 N NE2 . HIS   B 1 32  ? 0.11860   -30.11120 -29.73583 1.000 59.11000  ? 246 HIS   B NE2 1 
ATOM   2040 N N   . LEU   B 1 33  ? 2.32421   -27.26221 -27.18834 1.000 50.28000  ? 247 LEU   B N   1 
ATOM   2041 C CA  . LEU   B 1 33  ? 2.50087   -26.13815 -28.09633 1.000 47.46000  ? 247 LEU   B CA  1 
ATOM   2042 C C   . LEU   B 1 33  ? 2.03747   -26.52610 -29.50021 1.000 50.31000  ? 247 LEU   B C   1 
ATOM   2043 O O   . LEU   B 1 33  ? 2.52835   -27.50104 -30.07841 1.000 54.44000  ? 247 LEU   B O   1 
ATOM   2044 C CB  . LEU   B 1 33  ? 3.95784   -25.69307 -28.12274 1.000 47.08000  ? 247 LEU   B CB  1 
ATOM   2045 C CG  . LEU   B 1 33  ? 4.64322   -25.36010 -26.79293 1.000 48.74000  ? 247 LEU   B CG  1 
ATOM   2046 C CD1 . LEU   B 1 33  ? 6.06410   -24.95800 -27.10434 1.000 55.14000  ? 247 LEU   B CD1 1 
ATOM   2047 C CD2 . LEU   B 1 33  ? 3.94339   -24.25619 -26.01966 1.000 45.88000  ? 247 LEU   B CD2 1 
ATOM   2048 N N   . PHE   B 1 34  ? 1.08526   -25.77012 -30.03587 1.000 45.72000  ? 248 PHE   B N   1 
ATOM   2049 C CA  . PHE   B 1 34  ? 0.67185   -25.97107 -31.41676 1.000 49.74000  ? 248 PHE   B CA  1 
ATOM   2050 C C   . PHE   B 1 34  ? 1.70252   -25.38495 -32.38304 1.000 52.00000  ? 248 PHE   B C   1 
ATOM   2051 O O   . PHE   B 1 34  ? 2.18428   -26.06187 -33.30423 1.000 52.66000  ? 248 PHE   B O   1 
ATOM   2052 C CB  . PHE   B 1 34  ? -0.68726  -25.31813 -31.65431 1.000 47.84000  ? 248 PHE   B CB  1 
ATOM   2053 C CG  . PHE   B 1 34  ? -1.81297  -25.84625 -30.79000 1.000 51.48000  ? 248 PHE   B CG  1 
ATOM   2054 C CD1 . PHE   B 1 34  ? -2.39897  -27.08527 -31.05689 1.000 50.81000  ? 248 PHE   B CD1 1 
ATOM   2055 C CD2 . PHE   B 1 34  ? -2.34670  -25.06034 -29.76279 1.000 49.64000  ? 248 PHE   B CD2 1 
ATOM   2056 C CE1 . PHE   B 1 34  ? -3.46772  -27.55237 -30.29859 1.000 48.46000  ? 248 PHE   B CE1 1 
ATOM   2057 C CE2 . PHE   B 1 34  ? -3.41244  -25.50944 -29.00349 1.000 46.08000  ? 248 PHE   B CE2 1 
ATOM   2058 C CZ  . PHE   B 1 34  ? -3.97645  -26.76446 -29.26839 1.000 51.41000  ? 248 PHE   B CZ  1 
ATOM   2059 N N   . VAL   B 1 35  ? 2.02150   -24.11094 -32.20906 1.000 46.28000  ? 249 VAL   B N   1 
ATOM   2060 C CA  . VAL   B 1 35  ? 3.03323   -23.42084 -32.98733 1.000 44.89000  ? 249 VAL   B CA  1 
ATOM   2061 C C   . VAL   B 1 35  ? 3.91649   -22.70384 -31.97356 1.000 50.96000  ? 249 VAL   B C   1 
ATOM   2062 O O   . VAL   B 1 35  ? 3.45380   -22.32593 -30.88940 1.000 51.21000  ? 249 VAL   B O   1 
ATOM   2063 C CB  . VAL   B 1 35  ? 2.39485   -22.45281 -34.02608 1.000 42.13000  ? 249 VAL   B CB  1 
ATOM   2064 C CG1 . VAL   B 1 35  ? 1.58960   -23.24980 -35.02988 1.000 41.94000  ? 249 VAL   B CG1 1 
ATOM   2065 C CG2 . VAL   B 1 35  ? 1.49800   -21.41291 -33.34775 1.000 42.04000  ? 249 VAL   B CG2 1 
ATOM   2066 N N   . HIS   B 1 36  ? 5.20538   -22.55875 -32.30394 1.000 49.97000  ? 250 HIS   B N   1 
ATOM   2067 C CA  . HIS   B 1 36  ? 6.17563   -21.99775 -31.37120 1.000 46.25000  ? 250 HIS   B CA  1 
ATOM   2068 C C   . HIS   B 1 36  ? 7.33036   -21.37664 -32.14852 1.000 51.00000  ? 250 HIS   B C   1 
ATOM   2069 O O   . HIS   B 1 36  ? 7.87211   -21.98055 -33.07872 1.000 54.00000  ? 250 HIS   B O   1 
ATOM   2070 C CB  . HIS   B 1 36  ? 6.70999   -23.06277 -30.39943 1.000 47.26000  ? 250 HIS   B CB  1 
ATOM   2071 C CG  . HIS   B 1 36  ? 7.74925   -22.55477 -29.44271 1.000 55.25000  ? 250 HIS   B CG  1 
ATOM   2072 N ND1 . HIS   B 1 36  ? 7.46750   -21.64284 -28.44457 1.000 59.16000  ? 250 HIS   B ND1 1 
ATOM   2073 C CD2 . HIS   B 1 36  ? 9.07729   -22.80070 -29.35513 1.000 58.87000  ? 250 HIS   B CD2 1 
ATOM   2074 C CE1 . HIS   B 1 36  ? 8.56869   -21.37182 -27.76889 1.000 59.80000  ? 250 HIS   B CE1 1 
ATOM   2075 N NE2 . HIS   B 1 36  ? 9.56357   -22.05473 -28.30624 1.000 59.97000  ? 250 HIS   B NE2 1 
ATOM   2076 N N   . ILE   B 1 37  ? 7.68240   -20.15264 -31.77155 1.000 51.35000  ? 251 ILE   B N   1 
ATOM   2077 C CA  . ILE   B 1 37  ? 8.90924   -19.49454 -32.19389 1.000 50.79000  ? 251 ILE   B CA  1 
ATOM   2078 C C   . ILE   B 1 37  ? 9.63060   -19.10557 -30.91409 1.000 56.60000  ? 251 ILE   B C   1 
ATOM   2079 O O   . ILE   B 1 37  ? 9.08281   -18.35965 -30.09188 1.000 55.96000  ? 251 ILE   B O   1 
ATOM   2080 C CB  . ILE   B 1 37  ? 8.63891   -18.24651 -33.04873 1.000 49.53000  ? 251 ILE   B CB  1 
ATOM   2081 C CG1 . ILE   B 1 37  ? 8.23650   -18.62545 -34.45763 1.000 46.66000  ? 251 ILE   B CG1 1 
ATOM   2082 C CG2 . ILE   B 1 37  ? 9.89683   -17.36443 -33.13307 1.000 49.20000  ? 251 ILE   B CG2 1 
ATOM   2083 C CD1 . ILE   B 1 37  ? 7.71020   -17.43844 -35.23141 1.000 43.34000  ? 251 ILE   B CD1 1 
ATOM   2084 N N   . GLY   B 1 38  ? 10.85268  -19.56851 -30.73948 1.000 64.74000  ? 252 GLY   B N   1 
ATOM   2085 C CA  . GLY   B 1 38  ? 11.61802  -19.17754 -29.57369 1.000 69.52000  ? 252 GLY   B CA  1 
ATOM   2086 C C   . GLY   B 1 38  ? 13.08092  -18.94243 -29.84412 1.000 75.88000  ? 252 GLY   B C   1 
ATOM   2087 O O   . GLY   B 1 38  ? 13.61765  -19.44535 -30.81832 1.000 84.84000  ? 252 GLY   B O   1 
ATOM   2088 N N   . GLN   B 1 39  ? 13.73313  -18.15644 -29.00328 1.000 85.06000  ? 253 GLN   B N   1 
ATOM   2089 C CA  . GLN   B 1 39  ? 15.15507  -17.96135 -29.16170 1.000 91.59000  ? 253 GLN   B CA  1 
ATOM   2090 C C   . GLN   B 1 39  ? 15.82447  -18.47838 -27.93793 1.000 100.79000 ? 253 GLN   B C   1 
ATOM   2091 O O   . GLN   B 1 39  ? 15.47279  -18.08847 -26.82980 1.000 104.34000 ? 253 GLN   B O   1 
ATOM   2092 C CB  . GLN   B 1 39  ? 15.47694  -16.48633 -29.30771 1.000 92.34000  ? 253 GLN   B CB  1 
ATOM   2093 C CG  . GLN   B 1 39  ? 14.69856  -15.79631 -30.41343 1.000 95.17000  ? 253 GLN   B CG  1 
ATOM   2094 C CD  . GLN   B 1 39  ? 15.17840  -14.38526 -30.67050 1.000 89.38000  ? 253 GLN   B CD  1 
ATOM   2095 O OE1 . GLN   B 1 39  ? 16.22053  -13.97223 -30.16979 1.000 96.24000  ? 253 GLN   B OE1 1 
ATOM   2096 N NE2 . GLN   B 1 39  ? 14.42112  -13.63926 -31.46222 1.000 76.14000  ? 253 GLN   B NE2 1 
ATOM   2097 N N   . THR   B 1 40  ? 16.80047  -19.35532 -28.11928 1.000 107.74000 ? 254 THR   B N   1 
ATOM   2098 C CA  . THR   B 1 40  ? 17.55584  -19.87134 -26.98754 1.000 114.66000 ? 254 THR   B CA  1 
ATOM   2099 C C   . THR   B 1 40  ? 18.29898  -18.74133 -26.32970 1.000 114.19000 ? 254 THR   B C   1 
ATOM   2100 O O   . THR   B 1 40  ? 18.35834  -18.64740 -25.10471 1.000 110.44000 ? 254 THR   B O   1 
ATOM   2101 C CB  . THR   B 1 40  ? 18.56376  -20.93425 -27.45690 1.000 110.56000 ? 254 THR   B CB  1 
ATOM   2102 O OG1 . THR   B 1 40  ? 17.87660  -21.96925 -28.17176 1.000 104.01000 ? 254 THR   B OG1 1 
ATOM   2103 C CG2 . THR   B 1 40  ? 19.28916  -21.53928 -26.27116 1.000 108.06000 ? 254 THR   B CG2 1 
ATOM   2104 N N   . ASN   B 1 41  ? 18.86668  -17.87425 -27.14582 1.000 115.88000 ? 255 ASN   B N   1 
ATOM   2105 C CA  . ASN   B 1 41  ? 19.61376  -16.74724 -26.65698 1.000 112.24000 ? 255 ASN   B CA  1 
ATOM   2106 C C   . ASN   B 1 41  ? 19.31939  -15.75619 -27.70184 1.000 110.36000 ? 255 ASN   B C   1 
ATOM   2107 O O   . ASN   B 1 41  ? 18.90107  -16.11316 -28.80373 1.000 109.17000 ? 255 ASN   B O   1 
ATOM   2108 C CB  . ASN   B 1 41  ? 21.08477  -17.05415 -26.69445 1.000 110.97000 ? 255 ASN   B CB  1 
ATOM   2109 C CG  . ASN   B 1 41  ? 21.58635  -17.27304 -28.10761 1.000 118.38000 ? 255 ASN   B CG  1 
ATOM   2110 O OD1 . ASN   B 1 41  ? 21.06518  -18.11603 -28.83950 1.000 118.69000 ? 255 ASN   B OD1 1 
ATOM   2111 N ND2 . ASN   B 1 41  ? 22.59419  -16.50596 -28.50487 1.000 112.72000 ? 255 ASN   B ND2 1 
ATOM   2112 N N   . PRO   B 1 42  ? 19.50141  -14.47220 -27.37682 1.000 107.82000 ? 256 PRO   B N   1 
ATOM   2113 C CA  . PRO   B 1 42  ? 19.23201  -13.64715 -28.53169 1.000 104.90000 ? 256 PRO   B CA  1 
ATOM   2114 C C   . PRO   B 1 42  ? 20.30276  -14.12204 -29.45604 1.000 110.23000 ? 256 PRO   B C   1 
ATOM   2115 O O   . PRO   B 1 42  ? 21.47387  -14.14899 -29.09940 1.000 109.32000 ? 256 PRO   B O   1 
ATOM   2116 C CB  . PRO   B 1 42  ? 19.52108  -12.24716 -28.03669 1.000 99.17000  ? 256 PRO   B CB  1 
ATOM   2117 C CG  . PRO   B 1 42  ? 19.20553  -12.31227 -26.57960 1.000 101.89000 ? 256 PRO   B CG  1 
ATOM   2118 C CD  . PRO   B 1 42  ? 19.60774  -13.69127 -26.13580 1.000 103.80000 ? 256 PRO   B CD  1 
ATOM   2119 N N   . ALA   B 1 43  ? 19.91341  -14.45899 -30.66394 1.000 110.62000 ? 257 ALA   B N   1 
ATOM   2120 C CA  . ALA   B 1 43  ? 20.85914  -14.95088 -31.63126 1.000 108.57000 ? 257 ALA   B CA  1 
ATOM   2121 C C   . ALA   B 1 43  ? 21.61890  -13.82980 -32.22242 1.000 110.28000 ? 257 ALA   B C   1 
ATOM   2122 O O   . ALA   B 1 43  ? 21.13582  -12.70383 -32.26421 1.000 111.67000 ? 257 ALA   B O   1 
ATOM   2123 C CB  . ALA   B 1 43  ? 20.13786  -15.71686 -32.71908 1.000 106.13000 ? 257 ALA   B CB  1 
ATOM   2124 N N   . PHE   B 1 44  ? 22.79976  -14.11770 -32.73580 1.000 110.84000 ? 258 PHE   B N   1 
ATOM   2125 C CA  . PHE   B 1 44  ? 23.47748  -13.08562 -33.45794 1.000 106.51000 ? 258 PHE   B CA  1 
ATOM   2126 C C   . PHE   B 1 44  ? 22.40417  -13.03862 -34.49062 1.000 106.62000 ? 258 PHE   B C   1 
ATOM   2127 O O   . PHE   B 1 44  ? 21.89110  -14.08363 -34.90952 1.000 104.50000 ? 258 PHE   B O   1 
ATOM   2128 C CB  . PHE   B 1 44  ? 24.78933  -13.55551 -34.03837 1.000 105.77000 ? 258 PHE   B CB  1 
ATOM   2129 C CG  . PHE   B 1 44  ? 25.91064  -13.60450 -33.04571 1.000 118.16000 ? 258 PHE   B CG  1 
ATOM   2130 C CD1 . PHE   B 1 44  ? 25.67206  -13.91859 -31.71866 1.000 119.58000 ? 258 PHE   B CD1 1 
ATOM   2131 C CD2 . PHE   B 1 44  ? 27.21050  -13.34140 -33.44209 1.000 115.91000 ? 258 PHE   B CD2 1 
ATOM   2132 C CE1 . PHE   B 1 44  ? 26.70634  -13.96359 -30.80498 1.000 115.40000 ? 258 PHE   B CE1 1 
ATOM   2133 C CE2 . PHE   B 1 44  ? 28.24978  -13.38640 -32.53341 1.000 111.10000 ? 258 PHE   B CE2 1 
ATOM   2134 C CZ  . PHE   B 1 44  ? 27.99620  -13.69749 -31.21235 1.000 117.36000 ? 258 PHE   B CZ  1 
ATOM   2135 N N   . SER   B 1 45  ? 22.08894  -11.87061 -35.00945 1.000 97.20000  ? 259 SER   B N   1 
ATOM   2136 C CA  . SER   B 1 45  ? 20.93768  -11.81663 -35.85510 1.000 80.44000  ? 259 SER   B CA  1 
ATOM   2137 C C   . SER   B 1 45  ? 21.14539  -12.75755 -36.97722 1.000 79.05000  ? 259 SER   B C   1 
ATOM   2138 O O   . SER   B 1 45  ? 22.22623  -12.84546 -37.53455 1.000 83.39000  ? 259 SER   B O   1 
ATOM   2139 C CB  . SER   B 1 45  ? 20.80042  -10.42560 -36.42798 1.000 79.39000  ? 259 SER   B CB  1 
ATOM   2140 O OG  . SER   B 1 45  ? 21.82913  -10.16949 -37.36228 1.000 82.57000  ? 259 SER   B OG  1 
ATOM   2141 N N   . ASP   B 1 46  ? 20.09834  -13.49359 -37.29694 1.000 73.39000  ? 260 ASP   B N   1 
ATOM   2142 C CA  . ASP   B 1 46  ? 20.15907  -14.43253 -38.36901 1.000 69.55000  ? 260 ASP   B CA  1 
ATOM   2143 C C   . ASP   B 1 46  ? 18.95082  -14.06856 -39.12963 1.000 63.08000  ? 260 ASP   B C   1 
ATOM   2144 O O   . ASP   B 1 46  ? 17.95987  -14.76662 -39.08837 1.000 62.86000  ? 260 ASP   B O   1 
ATOM   2145 C CB  . ASP   B 1 46  ? 20.02930  -15.85857 -37.86406 1.000 66.05000  ? 260 ASP   B CB  1 
ATOM   2146 C CG  . ASP   B 1 46  ? 20.21803  -16.88349 -38.96317 1.000 66.77000  ? 260 ASP   B CG  1 
ATOM   2147 O OD1 . ASP   B 1 46  ? 20.50066  -16.49141 -40.11224 1.000 65.89000  ? 260 ASP   B OD1 1 
ATOM   2148 O OD2 . ASP   B 1 46  ? 20.08819  -18.08452 -38.67720 1.000 66.02000  ? 260 ASP   B OD2 1 
ATOM   2149 N N   . PRO   B 1 47  ? 19.01354  -12.94051 -39.81358 1.000 56.78000  ? 261 PRO   B N   1 
ATOM   2150 C CA  . PRO   B 1 47  ? 17.84130  -12.47954 -40.52320 1.000 57.31000  ? 261 PRO   B CA  1 
ATOM   2151 C C   . PRO   B 1 47  ? 17.52600  -13.40249 -41.68916 1.000 59.08000  ? 261 PRO   B C   1 
ATOM   2152 O O   . PRO   B 1 47  ? 18.41989  -14.07041 -42.18147 1.000 61.85000  ? 261 PRO   B O   1 
ATOM   2153 C CB  . PRO   B 1 47  ? 18.28407  -11.12848 -41.02725 1.000 53.52000  ? 261 PRO   B CB  1 
ATOM   2154 C CG  . PRO   B 1 47  ? 19.74902  -11.24939 -41.21071 1.000 59.12000  ? 261 PRO   B CG  1 
ATOM   2155 C CD  . PRO   B 1 47  ? 20.18342  -12.08543 -40.05489 1.000 60.01000  ? 261 PRO   B CD  1 
ATOM   2156 N N   . PRO   B 1 48  ? 16.26388  -13.46754 -42.10778 1.000 56.07000  ? 262 PRO   B N   1 
ATOM   2157 C CA  . PRO   B 1 48  ? 15.96660  -14.40449 -43.19374 1.000 55.28000  ? 262 PRO   B CA  1 
ATOM   2158 C C   . PRO   B 1 48  ? 16.74120  -14.02638 -44.44695 1.000 51.48000  ? 262 PRO   B C   1 
ATOM   2159 O O   . PRO   B 1 48  ? 16.86903  -12.84735 -44.78392 1.000 55.88000  ? 262 PRO   B O   1 
ATOM   2160 C CB  . PRO   B 1 48  ? 14.44654  -14.28257 -43.37827 1.000 51.43000  ? 262 PRO   B CB  1 
ATOM   2161 C CG  . PRO   B 1 48  ? 14.09964  -12.97263 -42.78109 1.000 48.58000  ? 262 PRO   B CG  1 
ATOM   2162 C CD  . PRO   B 1 48  ? 15.04497  -12.77464 -41.64937 1.000 55.55000  ? 262 PRO   B CD  1 
ATOM   2163 N N   . LEU   B 1 49  ? 17.30806  -15.03531 -45.09518 1.000 51.75000  ? 263 LEU   B N   1 
ATOM   2164 C CA  . LEU   B 1 49  ? 17.91665  -14.89420 -46.41236 1.000 52.44000  ? 263 LEU   B CA  1 
ATOM   2165 C C   . LEU   B 1 49  ? 16.97435  -15.39219 -47.50810 1.000 52.19000  ? 263 LEU   B C   1 
ATOM   2166 O O   . LEU   B 1 49  ? 17.29098  -15.30010 -48.69919 1.000 55.74000  ? 263 LEU   B O   1 
ATOM   2167 C CB  . LEU   B 1 49  ? 19.24568  -15.65612 -46.45281 1.000 49.16000  ? 263 LEU   B CB  1 
ATOM   2168 C CG  . LEU   B 1 49  ? 20.33196  -15.18311 -45.46411 1.000 60.26000  ? 263 LEU   B CG  1 
ATOM   2169 C CD1 . LEU   B 1 49  ? 21.65494  -15.92502 -45.67456 1.000 59.42000  ? 263 LEU   B CD1 1 
ATOM   2170 C CD2 . LEU   B 1 49  ? 20.54287  -13.65310 -45.45409 1.000 60.50000  ? 263 LEU   B CD2 1 
ATOM   2171 N N   . GLU   B 1 50  ? 15.81850  -15.90228 -47.11078 1.000 53.25000  ? 264 GLU   B N   1 
ATOM   2172 C CA  . GLU   B 1 50  ? 14.79126  -16.43329 -47.98450 1.000 49.46000  ? 264 GLU   B CA  1 
ATOM   2173 C C   . GLU   B 1 50  ? 13.70016  -15.38234 -48.11511 1.000 49.55000  ? 264 GLU   B C   1 
ATOM   2174 O O   . GLU   B 1 50  ? 13.20644  -14.87043 -47.10393 1.000 52.70000  ? 264 GLU   B O   1 
ATOM   2175 C CB  . GLU   B 1 50  ? 14.23452  -17.72635 -47.38841 1.000 51.72000  ? 264 GLU   B CB  1 
ATOM   2176 C CG  . GLU   B 1 50  ? 15.31166  -18.78031 -47.12879 1.000 51.36000  ? 264 GLU   B CG  1 
ATOM   2177 C CD  . GLU   B 1 50  ? 16.01506  -18.61434 -45.79300 1.000 51.38000  ? 264 GLU   B CD  1 
ATOM   2178 O OE1 . GLU   B 1 50  ? 15.76721  -17.60340 -45.09886 1.000 50.49000  ? 264 GLU   B OE1 1 
ATOM   2179 O OE2 . GLU   B 1 50  ? 16.83621  -19.48931 -45.44830 1.000 53.49000  ? 264 GLU   B OE2 1 
ATOM   2180 N N   . ALA   B 1 51  ? 13.33777  -15.04729 -49.34898 1.000 44.32000  ? 265 ALA   B N   1 
ATOM   2181 C CA  . ALA   B 1 51  ? 12.41062  -13.96133 -49.61763 1.000 47.04000  ? 265 ALA   B CA  1 
ATOM   2182 C C   . ALA   B 1 51  ? 11.20942  -14.47336 -50.39330 1.000 49.40000  ? 265 ALA   B C   1 
ATOM   2183 O O   . ALA   B 1 51  ? 11.32422  -15.39730 -51.21139 1.000 49.64000  ? 265 ALA   B O   1 
ATOM   2184 C CB  . ALA   B 1 51  ? 13.07632  -12.83025 -50.40477 1.000 45.37000  ? 265 ALA   B CB  1 
ATOM   2185 N N   . VAL   B 1 52  ? 10.06346  -13.86144 -50.12191 1.000 47.61000  ? 266 VAL   B N   1 
ATOM   2186 C CA  . VAL   B 1 52  ? 8.84324   -14.06046 -50.88856 1.000 47.16000  ? 266 VAL   B CA  1 
ATOM   2187 C C   . VAL   B 1 52  ? 8.27706   -12.68848 -51.23130 1.000 48.59000  ? 266 VAL   B C   1 
ATOM   2188 O O   . VAL   B 1 52  ? 8.23426   -11.78953 -50.38024 1.000 49.33000  ? 266 VAL   B O   1 
ATOM   2189 C CB  . VAL   B 1 52  ? 7.83153   -14.92457 -50.11230 1.000 47.67000  ? 266 VAL   B CB  1 
ATOM   2190 C CG1 . VAL   B 1 52  ? 6.43834   -14.79362 -50.70887 1.000 45.15000  ? 266 VAL   B CG1 1 
ATOM   2191 C CG2 . VAL   B 1 52  ? 8.29861   -16.37854 -50.12652 1.000 43.61000  ? 266 VAL   B CG2 1 
ATOM   2192 N N   . ASP   B 1 53  ? 7.89766   -12.51343 -52.49718 1.000 48.29000  ? 267 ASP   B N   1 
ATOM   2193 C CA  . ASP   B 1 53  ? 7.27746   -11.27044 -52.92592 1.000 50.87000  ? 267 ASP   B CA  1 
ATOM   2194 C C   . ASP   B 1 53  ? 5.90065   -11.14656 -52.28849 1.000 53.15000  ? 267 ASP   B C   1 
ATOM   2195 O O   . ASP   B 1 53  ? 5.07466   -12.05360 -52.41329 1.000 51.75000  ? 267 ASP   B O   1 
ATOM   2196 C CB  . ASP   B 1 53  ? 7.16700   -11.23736 -54.44888 1.000 56.49000  ? 267 ASP   B CB  1 
ATOM   2197 C CG  . ASP   B 1 53  ? 6.86775   -9.84434  -54.98471 1.000 59.85000  ? 267 ASP   B CG  1 
ATOM   2198 O OD1 . ASP   B 1 53  ? 6.20892   -9.04742  -54.27647 1.000 62.37000  ? 267 ASP   B OD1 1 
ATOM   2199 O OD2 . ASP   B 1 53  ? 7.33640   -9.52425  -56.09784 1.000 63.56000  ? 267 ASP   B OD2 1 
ATOM   2200 N N   . VAL   B 1 54  ? 5.65379   -10.02161 -51.60835 1.000 50.67000  ? 268 VAL   B N   1 
ATOM   2201 C CA  . VAL   B 1 54  ? 4.40801   -9.88172  -50.85797 1.000 52.93000  ? 268 VAL   B CA  1 
ATOM   2202 C C   . VAL   B 1 54  ? 3.20873   -9.94274  -51.78461 1.000 55.61000  ? 268 VAL   B C   1 
ATOM   2203 O O   . VAL   B 1 54  ? 2.14088   -10.43583 -51.39531 1.000 54.21000  ? 268 VAL   B O   1 
ATOM   2204 C CB  . VAL   B 1 54  ? 4.39318   -8.58177  -50.02789 1.000 57.35000  ? 268 VAL   B CB  1 
ATOM   2205 C CG1 . VAL   B 1 54  ? 4.44484   -7.35072  -50.93983 1.000 52.95000  ? 268 VAL   B CG1 1 
ATOM   2206 C CG2 . VAL   B 1 54  ? 3.14445   -8.54490  -49.14251 1.000 53.42000  ? 268 VAL   B CG2 1 
ATOM   2207 N N   . ARG   B 1 55  ? 3.35833   -9.45966  -53.02162 1.000 53.89000  ? 269 ARG   B N   1 
ATOM   2208 C CA  . ARG   B 1 55  ? 2.23604   -9.45867  -53.95028 1.000 54.01000  ? 269 ARG   B CA  1 
ATOM   2209 C C   . ARG   B 1 55  ? 1.67507   -10.85269 -54.14719 1.000 53.31000  ? 269 ARG   B C   1 
ATOM   2210 O O   . ARG   B 1 55  ? 0.46901   -11.01175 -54.35184 1.000 54.73000  ? 269 ARG   B O   1 
ATOM   2211 C CB  . ARG   B 1 55  ? 2.66260   -8.87757  -55.29138 1.000 53.96000  ? 269 ARG   B CB  1 
ATOM   2212 C CG  . ARG   B 1 55  ? 3.01354   -7.42255  -55.21840 1.000 56.09000  ? 269 ARG   B CG  1 
ATOM   2213 C CD  . ARG   B 1 55  ? 3.75214   -7.00044  -56.44960 1.000 56.04000  ? 269 ARG   B CD  1 
ATOM   2214 N NE  . ARG   B 1 55  ? 5.19819   -7.11736  -56.30005 1.000 58.96000  ? 269 ARG   B NE  1 
ATOM   2215 C CZ  . ARG   B 1 55  ? 6.06491   -6.57926  -57.14528 1.000 59.03000  ? 269 ARG   B CZ  1 
ATOM   2216 N NH1 . ARG   B 1 55  ? 5.65455   -5.87723  -58.18511 1.000 60.65000  ? 269 ARG   B NH1 1 
ATOM   2217 N NH2 . ARG   B 1 55  ? 7.37298   -6.73620  -56.93469 1.000 57.94000  ? 269 ARG   B NH2 1 
ATOM   2218 N N   . GLN   B 1 56  ? 2.52415   -11.86965 -54.07051 1.000 48.40000  ? 270 GLN   B N   1 
ATOM   2219 C CA  . GLN   B 1 56  ? 2.04817   -13.22467 -54.26444 1.000 49.96000  ? 270 GLN   B CA  1 
ATOM   2220 C C   . GLN   B 1 56  ? 1.10253   -13.67878 -53.15218 1.000 54.05000  ? 270 GLN   B C   1 
ATOM   2221 O O   . GLN   B 1 56  ? 0.45355   -14.72181 -53.28505 1.000 52.55000  ? 270 GLN   B O   1 
ATOM   2222 C CB  . GLN   B 1 56  ? 3.24120   -14.17059 -54.35486 1.000 48.62000  ? 270 GLN   B CB  1 
ATOM   2223 C CG  . GLN   B 1 56  ? 4.18983   -13.89147 -55.51213 1.000 60.42000  ? 270 GLN   B CG  1 
ATOM   2224 C CD  . GLN   B 1 56  ? 3.55542   -14.09543 -56.87795 1.000 69.58000  ? 270 GLN   B CD  1 
ATOM   2225 O OE1 . GLN   B 1 56  ? 2.80522   -13.24544 -57.37667 1.000 70.42000  ? 270 GLN   B OE1 1 
ATOM   2226 N NE2 . GLN   B 1 56  ? 3.86130   -15.23237 -57.49611 1.000 74.98000  ? 270 GLN   B NE2 1 
ATOM   2227 N N   . ILE   B 1 57  ? 1.00383   -12.95185 -52.04811 1.000 53.90000  ? 271 ILE   B N   1 
ATOM   2228 C CA  . ILE   B 1 57  ? 0.18919   -13.44997 -50.94989 1.000 53.00000  ? 271 ILE   B CA  1 
ATOM   2229 C C   . ILE   B 1 57  ? -0.90976  -12.44705 -50.57950 1.000 57.03000  ? 271 ILE   B C   1 
ATOM   2230 O O   . ILE   B 1 57  ? -1.51443  -12.53915 -49.50432 1.000 51.13000  ? 271 ILE   B O   1 
ATOM   2231 C CB  . ILE   B 1 57  ? 1.07058   -13.87598 -49.75318 1.000 48.08000  ? 271 ILE   B CB  1 
ATOM   2232 C CG1 . ILE   B 1 57  ? 1.87670   -12.73997 -49.11936 1.000 49.46000  ? 271 ILE   B CG1 1 
ATOM   2233 C CG2 . ILE   B 1 57  ? 2.09051   -14.93690 -50.18755 1.000 46.49000  ? 271 ILE   B CG2 1 
ATOM   2234 C CD1 . ILE   B 1 57  ? 1.33207   -12.28008 -47.81717 1.000 49.00000  ? 271 ILE   B CD1 1 
ATOM   2235 N N   . TYR   B 1 58  ? -1.22810  -11.53402 -51.51335 1.000 55.45000  ? 272 TYR   B N   1 
ATOM   2236 C CA  . TYR   B 1 58  ? -2.26109  -10.52609 -51.28798 1.000 55.80000  ? 272 TYR   B CA  1 
ATOM   2237 C C   . TYR   B 1 58  ? -3.65502  -11.15018 -51.18059 1.000 57.15000  ? 272 TYR   B C   1 
ATOM   2238 O O   . TYR   B 1 58  ? -4.54686  -10.56426 -50.56129 1.000 53.64000  ? 272 TYR   B O   1 
ATOM   2239 C CB  . TYR   B 1 58  ? -2.22549  -9.50402  -52.42393 1.000 57.78000  ? 272 TYR   B CB  1 
ATOM   2240 C CG  . TYR   B 1 58  ? -1.22753  -8.35697  -52.32617 1.000 57.66000  ? 272 TYR   B CG  1 
ATOM   2241 C CD1 . TYR   B 1 58  ? -0.61818  -7.99900  -51.12533 1.000 58.02000  ? 272 TYR   B CD1 1 
ATOM   2242 C CD2 . TYR   B 1 58  ? -0.90792  -7.61588  -53.46622 1.000 62.37000  ? 272 TYR   B CD2 1 
ATOM   2243 C CE1 . TYR   B 1 58  ? 0.30577   -6.92495  -51.06655 1.000 60.78000  ? 272 TYR   B CE1 1 
ATOM   2244 C CE2 . TYR   B 1 58  ? 0.00103   -6.55683  -53.42644 1.000 62.81000  ? 272 TYR   B CE2 1 
ATOM   2245 C CZ  . TYR   B 1 58  ? 0.60038   -6.20687  -52.23560 1.000 66.92000  ? 272 TYR   B CZ  1 
ATOM   2246 O OH  . TYR   B 1 58  ? 1.48231   -5.13681  -52.25180 1.000 66.88000  ? 272 TYR   B OH  1 
ATOM   2247 N N   . ASP   B 1 59  ? -3.86513  -12.32415 -51.77759 1.000 54.51000  ? 273 ASP   B N   1 
ATOM   2248 C CA  . ASP   B 1 59  ? -5.18309  -12.94223 -51.77323 1.000 54.04000  ? 273 ASP   B CA  1 
ATOM   2249 C C   . ASP   B 1 59  ? -5.44966  -13.75332 -50.51320 1.000 56.99000  ? 273 ASP   B C   1 
ATOM   2250 O O   . ASP   B 1 59  ? -6.58258  -14.20540 -50.31388 1.000 60.14000  ? 273 ASP   B O   1 
ATOM   2251 C CB  . ASP   B 1 59  ? -5.34740  -13.87717 -52.96823 1.000 55.48000  ? 273 ASP   B CB  1 
ATOM   2252 C CG  . ASP   B 1 59  ? -4.11343  -14.71108 -53.21966 1.000 67.83000  ? 273 ASP   B CG  1 
ATOM   2253 O OD1 . ASP   B 1 59  ? -2.99140  -14.18403 -53.03297 1.000 69.40000  ? 273 ASP   B OD1 1 
ATOM   2254 O OD2 . ASP   B 1 59  ? -4.25648  -15.89407 -53.60968 1.000 75.42000  ? 273 ASP   B OD2 1 
ATOM   2255 N N   . LYS   B 1 60  ? -4.43440  -13.98531 -49.67852 1.000 57.23000  ? 274 LYS   B N   1 
ATOM   2256 C CA  . LYS   B 1 60  ? -4.60098  -14.74439 -48.44151 1.000 51.01000  ? 274 LYS   B CA  1 
ATOM   2257 C C   . LYS   B 1 60  ? -4.87566  -13.85648 -47.23138 1.000 49.94000  ? 274 LYS   B C   1 
ATOM   2258 O O   . LYS   B 1 60  ? -4.94829  -14.36154 -46.11038 1.000 53.31000  ? 274 LYS   B O   1 
ATOM   2259 C CB  . LYS   B 1 60  ? -3.35684  -15.60333 -48.17194 1.000 43.43000  ? 274 LYS   B CB  1 
ATOM   2260 C CG  . LYS   B 1 60  ? -2.99714  -16.50324 -49.32910 1.000 48.89000  ? 274 LYS   B CG  1 
ATOM   2261 C CD  . LYS   B 1 60  ? -1.89998  -17.46820 -48.98549 1.000 48.06000  ? 274 LYS   B CD  1 
ATOM   2262 C CE  . LYS   B 1 60  ? -2.35683  -18.90724 -48.76743 1.000 49.95000  ? 274 LYS   B CE  1 
ATOM   2263 N NZ  . LYS   B 1 60  ? -3.18345  -19.11636 -47.56619 1.000 43.42000  ? 274 LYS   B NZ  1 
ATOM   2264 N N   . PHE   B 1 61  ? -5.03680  -12.56647 -47.43925 1.000 49.19000  ? 275 PHE   B N   1 
ATOM   2265 C CA  . PHE   B 1 61  ? -5.23552  -11.65155 -46.34014 1.000 49.18000  ? 275 PHE   B CA  1 
ATOM   2266 C C   . PHE   B 1 61  ? -6.17871  -10.55258 -46.75979 1.000 52.48000  ? 275 PHE   B C   1 
ATOM   2267 O O   . PHE   B 1 61  ? -6.41308  -10.36752 -47.93771 1.000 55.84000  ? 275 PHE   B O   1 
ATOM   2268 C CB  . PHE   B 1 61  ? -3.89241  -11.09550 -45.89052 1.000 54.02000  ? 275 PHE   B CB  1 
ATOM   2269 C CG  . PHE   B 1 61  ? -2.99117  -12.12248 -45.28985 1.000 48.42000  ? 275 PHE   B CG  1 
ATOM   2270 C CD1 . PHE   B 1 61  ? -3.10275  -12.45456 -43.95783 1.000 44.60000  ? 275 PHE   B CD1 1 
ATOM   2271 C CD2 . PHE   B 1 61  ? -2.04937  -12.76538 -46.06117 1.000 43.13000  ? 275 PHE   B CD2 1 
ATOM   2272 C CE1 . PHE   B 1 61  ? -2.28452  -13.40655 -43.40114 1.000 45.78000  ? 275 PHE   B CE1 1 
ATOM   2273 C CE2 . PHE   B 1 61  ? -1.23014  -13.72436 -45.51348 1.000 47.68000  ? 275 PHE   B CE2 1 
ATOM   2274 C CZ  . PHE   B 1 61  ? -1.34872  -14.04445 -44.18046 1.000 46.26000  ? 275 PHE   B CZ  1 
ATOM   2275 N N   . PRO   B 1 62  ? -6.74346  -9.82167  -45.79258 1.000 57.41000  ? 276 PRO   B N   1 
ATOM   2276 C CA  . PRO   B 1 62  ? -7.75763  -8.84070  -46.18821 1.000 59.80000  ? 276 PRO   B CA  1 
ATOM   2277 C C   . PRO   B 1 62  ? -7.15196  -7.77862  -47.05133 1.000 61.38000  ? 276 PRO   B C   1 
ATOM   2278 O O   . PRO   B 1 62  ? -6.07589  -7.30057  -46.74363 1.000 62.77000  ? 276 PRO   B O   1 
ATOM   2279 C CB  . PRO   B 1 62  ? -8.21626  -8.26381  -44.85204 1.000 60.94000  ? 276 PRO   B CB  1 
ATOM   2280 C CG  . PRO   B 1 62  ? -7.83789  -9.28084  -43.83221 1.000 62.25000  ? 276 PRO   B CG  1 
ATOM   2281 C CD  . PRO   B 1 62  ? -6.56001  -9.86874  -44.33463 1.000 59.25000  ? 276 PRO   B CD  1 
ATOM   2282 N N   . GLU   B 1 63  ? -7.83331  -7.39960  -48.12310 1.000 65.80000  ? 277 GLU   B N   1 
ATOM   2283 C CA  . GLU   B 1 63  ? -7.18764  -6.47550  -49.05225 1.000 65.93000  ? 277 GLU   B CA  1 
ATOM   2284 C C   . GLU   B 1 63  ? -7.41076  -4.96851  -49.16409 1.000 67.63000  ? 277 GLU   B C   1 
ATOM   2285 O O   . GLU   B 1 63  ? -6.44282  -4.21645  -49.19334 1.000 71.50000  ? 277 GLU   B O   1 
ATOM   2286 C CB  . GLU   B 1 63  ? -7.49004  -7.02644  -50.45519 1.000 60.39000  ? 277 GLU   B CB  1 
ATOM   2287 C CG  . GLU   B 1 63  ? -7.24244  -6.05636  -51.60221 1.000 68.62000  ? 277 GLU   B CG  1 
ATOM   2288 C CD  . GLU   B 1 63  ? -8.46872  -5.86438  -52.48482 1.000 73.48000  ? 277 GLU   B CD  1 
ATOM   2289 O OE1 . GLU   B 1 63  ? -9.50760  -6.50646  -52.21854 1.000 84.63000  ? 277 GLU   B OE1 1 
ATOM   2290 O OE2 . GLU   B 1 63  ? -8.39706  -5.06832  -53.44980 1.000 73.94000  ? 277 GLU   B OE2 1 
ATOM   2291 N N   . LYS   B 1 64  ? -8.63681  -4.49858  -49.22869 1.000 66.00000  ? 278 LYS   B N   1 
ATOM   2292 C CA  . LYS   B 1 64  ? -8.78898  -3.06557  -49.52156 1.000 64.48000  ? 278 LYS   B CA  1 
ATOM   2293 C C   . LYS   B 1 64  ? -8.31176  -1.98360  -48.58765 1.000 66.34000  ? 278 LYS   B C   1 
ATOM   2294 O O   . LYS   B 1 64  ? -7.63495  -1.07253  -49.01580 1.000 68.80000  ? 278 LYS   B O   1 
ATOM   2295 C CB  . LYS   B 1 64  ? -10.27607 -2.78764  -49.74010 1.000 70.51000  ? 278 LYS   B CB  1 
ATOM   2296 C CG  . LYS   B 1 64  ? -10.93832 -3.70262  -50.75095 1.000 75.89000  ? 278 LYS   B CG  1 
ATOM   2297 C CD  . LYS   B 1 64  ? -12.44929 -3.59672  -50.63948 1.000 85.14000  ? 278 LYS   B CD  1 
ATOM   2298 C CE  . LYS   B 1 64  ? -13.15349 -4.65071  -51.47533 1.000 82.02000  ? 278 LYS   B CE  1 
ATOM   2299 N NZ  . LYS   B 1 64  ? -14.62141 -4.64181  -51.22288 1.000 73.86000  ? 278 LYS   B NZ  1 
ATOM   2300 N N   . LYS   B 1 65  ? -8.59337  -2.09569  -47.31357 1.000 70.53000  ? 279 LYS   B N   1 
ATOM   2301 C CA  . LYS   B 1 65  ? -8.21717  -1.00072  -46.44062 1.000 70.71000  ? 279 LYS   B CA  1 
ATOM   2302 C C   . LYS   B 1 65  ? -7.51077  -1.50874  -45.22886 1.000 70.15000  ? 279 LYS   B C   1 
ATOM   2303 O O   . LYS   B 1 65  ? -8.04151  -2.33882  -44.52075 1.000 67.75000  ? 279 LYS   B O   1 
ATOM   2304 C CB  . LYS   B 1 65  ? -9.43110  -0.18381  -46.06120 1.000 67.03000  ? 279 LYS   B CB  1 
ATOM   2305 C CG  . LYS   B 1 65  ? -9.16619  1.30621   -46.08120 1.000 74.65000  ? 279 LYS   B CG  1 
ATOM   2306 C CD  . LYS   B 1 65  ? -10.45922 2.09513   -46.01676 1.000 79.90000  ? 279 LYS   B CD  1 
ATOM   2307 C CE  . LYS   B 1 65  ? -10.18731 3.58815   -46.03775 1.000 81.90000  ? 279 LYS   B CE  1 
ATOM   2308 N NZ  . LYS   B 1 65  ? -9.41370  3.98526   -47.24497 1.000 85.34000  ? 279 LYS   B NZ  1 
ATOM   2309 N N   . GLY   B 1 66  ? -6.36771  -0.93470  -44.91118 1.000 71.02000  ? 280 GLY   B N   1 
ATOM   2310 C CA  . GLY   B 1 66  ? -5.59534  -1.47471  -43.81844 1.000 71.01000  ? 280 GLY   B CA  1 
ATOM   2311 C C   . GLY   B 1 66  ? -5.31837  -2.89868  -44.18661 1.000 68.12000  ? 280 GLY   B C   1 
ATOM   2312 O O   . GLY   B 1 66  ? -5.30007  -3.78872  -43.34567 1.000 66.45000  ? 280 GLY   B O   1 
ATOM   2313 N N   . GLY   B 1 67  ? -5.09175  -3.11559  -45.46669 1.000 69.00000  ? 281 GLY   B N   1 
ATOM   2314 C CA  . GLY   B 1 67  ? -4.80081  -4.43455  -45.92985 1.000 60.89000  ? 281 GLY   B CA  1 
ATOM   2315 C C   . GLY   B 1 67  ? -3.33387  -4.53545  -46.14931 1.000 57.17000  ? 281 GLY   B C   1 
ATOM   2316 O O   . GLY   B 1 67  ? -2.61292  -3.55141  -46.11947 1.000 59.39000  ? 281 GLY   B O   1 
ATOM   2317 N N   . LEU   B 1 68  ? -2.88587  -5.74141  -46.38551 1.000 56.71000  ? 282 LEU   B N   1 
ATOM   2318 C CA  . LEU   B 1 68  ? -1.45992  -5.96931  -46.57796 1.000 54.89000  ? 282 LEU   B CA  1 
ATOM   2319 C C   . LEU   B 1 68  ? -0.88429  -5.01922  -47.61908 1.000 53.30000  ? 282 LEU   B C   1 
ATOM   2320 O O   . LEU   B 1 68  ? 0.17973   -4.42117  -47.42037 1.000 58.24000  ? 282 LEU   B O   1 
ATOM   2321 C CB  . LEU   B 1 68  ? -1.22996  -7.42528  -46.98111 1.000 52.14000  ? 282 LEU   B CB  1 
ATOM   2322 C CG  . LEU   B 1 68  ? 0.22307   -7.87119  -46.98158 1.000 54.95000  ? 282 LEU   B CG  1 
ATOM   2323 C CD1 . LEU   B 1 68  ? 0.92141   -7.32522  -45.73776 1.000 47.88000  ? 282 LEU   B CD1 1 
ATOM   2324 C CD2 . LEU   B 1 68  ? 0.23716   -9.36419  -46.96567 1.000 50.60000  ? 282 LEU   B CD2 1 
ATOM   2325 N N   . LYS   B 1 69  ? -1.59264  -4.84520  -48.72685 1.000 54.71000  ? 283 LYS   B N   1 
ATOM   2326 C CA  . LYS   B 1 69  ? -1.04702  -4.05610  -49.81997 1.000 55.35000  ? 283 LYS   B CA  1 
ATOM   2327 C C   . LYS   B 1 69  ? -0.84697  -2.61512  -49.38595 1.000 53.58000  ? 283 LYS   B C   1 
ATOM   2328 O O   . LYS   B 1 69  ? 0.24095   -2.05204  -49.54425 1.000 59.15000  ? 283 LYS   B O   1 
ATOM   2329 C CB  . LYS   B 1 69  ? -1.96938  -4.16309  -51.03470 1.000 64.74000  ? 283 LYS   B CB  1 
ATOM   2330 C CG  . LYS   B 1 69  ? -1.66678  -3.20100  -52.16274 1.000 63.19000  ? 283 LYS   B CG  1 
ATOM   2331 C CD  . LYS   B 1 69  ? -2.66411  -3.37700  -53.29544 1.000 62.67000  ? 283 LYS   B CD  1 
ATOM   2332 C CE  . LYS   B 1 69  ? -2.55348  -2.23193  -54.29041 1.000 60.43000  ? 283 LYS   B CE  1 
ATOM   2333 N NZ  . LYS   B 1 69  ? -1.14561  -2.01583  -54.68683 1.000 58.91000  ? 283 LYS   B NZ  1 
ATOM   2334 N N   . GLU   B 1 70  ? -1.86382  -2.02321  -48.76961 1.000 55.29000  ? 284 GLU   B N   1 
ATOM   2335 C CA  . GLU   B 1 70  ? -1.72676  -0.64823  -48.30757 1.000 59.50000  ? 284 GLU   B CA  1 
ATOM   2336 C C   . GLU   B 1 70  ? -0.70342  -0.55123  -47.18487 1.000 58.01000  ? 284 GLU   B C   1 
ATOM   2337 O O   . GLU   B 1 70  ? 0.09554   0.39581   -47.14306 1.000 59.70000  ? 284 GLU   B O   1 
ATOM   2338 C CB  . GLU   B 1 70  ? -3.08165  -0.11433  -47.84913 1.000 63.05000  ? 284 GLU   B CB  1 
ATOM   2339 C CG  . GLU   B 1 70  ? -3.85802  0.57368   -48.94285 1.000 68.39000  ? 284 GLU   B CG  1 
ATOM   2340 C CD  . GLU   B 1 70  ? -5.16890  1.15358   -48.44742 1.000 81.37000  ? 284 GLU   B CD  1 
ATOM   2341 O OE1 . GLU   B 1 70  ? -5.48253  0.97949   -47.23833 1.000 77.03000  ? 284 GLU   B OE1 1 
ATOM   2342 O OE2 . GLU   B 1 70  ? -5.88419  1.76858   -49.28117 1.000 78.89000  ? 284 GLU   B OE2 1 
ATOM   2343 N N   . LEU   B 1 71  ? -0.71509  -1.52829  -46.26993 1.000 55.85000  ? 285 LEU   B N   1 
ATOM   2344 C CA  . LEU   B 1 71  ? 0.26425   -1.57229  -45.18823 1.000 56.29000  ? 285 LEU   B CA  1 
ATOM   2345 C C   . LEU   B 1 71  ? 1.68909   -1.61418  -45.71166 1.000 53.20000  ? 285 LEU   B C   1 
ATOM   2346 O O   . LEU   B 1 71  ? 2.57722   -0.95216  -45.15589 1.000 57.15000  ? 285 LEU   B O   1 
ATOM   2347 C CB  . LEU   B 1 71  ? 0.01359   -2.78736  -44.30222 1.000 55.92000  ? 285 LEU   B CB  1 
ATOM   2348 C CG  . LEU   B 1 71  ? -0.92808  -2.51748  -43.15692 1.000 51.59000  ? 285 LEU   B CG  1 
ATOM   2349 C CD1 . LEU   B 1 71  ? -1.44586  -3.83654  -42.67584 1.000 57.77000  ? 285 LEU   B CD1 1 
ATOM   2350 C CD2 . LEU   B 1 71  ? -0.15479  -1.80350  -42.07011 1.000 48.40000  ? 285 LEU   B CD2 1 
ATOM   2351 N N   . TYR   B 1 72  ? 1.93982   -2.41711  -46.75179 1.000 52.58000  ? 286 TYR   B N   1 
ATOM   2352 C CA  . TYR   B 1 72  ? 3.29266   -2.50500  -47.29220 1.000 56.81000  ? 286 TYR   B CA  1 
ATOM   2353 C C   . TYR   B 1 72  ? 3.67837   -1.22593  -48.01824 1.000 59.96000  ? 286 TYR   B C   1 
ATOM   2354 O O   . TYR   B 1 72  ? 4.85035   -0.82186  -47.99058 1.000 64.74000  ? 286 TYR   B O   1 
ATOM   2355 C CB  . TYR   B 1 72  ? 3.41745   -3.71994  -48.21631 1.000 52.59000  ? 286 TYR   B CB  1 
ATOM   2356 C CG  . TYR   B 1 72  ? 4.84340   -4.18484  -48.46777 1.000 56.25000  ? 286 TYR   B CG  1 
ATOM   2357 C CD1 . TYR   B 1 72  ? 5.61406   -3.61973  -49.48897 1.000 58.72000  ? 286 TYR   B CD1 1 
ATOM   2358 C CD2 . TYR   B 1 72  ? 5.42970   -5.18285  -47.68501 1.000 53.77000  ? 286 TYR   B CD2 1 
ATOM   2359 C CE1 . TYR   B 1 72  ? 6.92001   -4.03964  -49.72939 1.000 52.92000  ? 286 TYR   B CE1 1 
ATOM   2360 C CE2 . TYR   B 1 72  ? 6.72765   -5.60576  -47.91342 1.000 51.18000  ? 286 TYR   B CE2 1 
ATOM   2361 C CZ  . TYR   B 1 72  ? 7.46431   -5.03266  -48.94562 1.000 56.90000  ? 286 TYR   B CZ  1 
ATOM   2362 O OH  . TYR   B 1 72  ? 8.75626   -5.45257  -49.18903 1.000 58.26000  ? 286 TYR   B OH  1 
ATOM   2363 N N   . GLU   B 1 73  ? 2.70813   -0.57895  -48.68191 1.000 57.82000  ? 287 GLU   B N   1 
ATOM   2364 C CA  . GLU   B 1 73  ? 2.97186   0.70410   -49.32792 1.000 57.09000  ? 287 GLU   B CA  1 
ATOM   2365 C C   . GLU   B 1 73  ? 3.25511   1.78006   -48.28894 1.000 56.64000  ? 287 GLU   B C   1 
ATOM   2366 O O   . GLU   B 1 73  ? 4.14600   2.61812   -48.48216 1.000 54.05000  ? 287 GLU   B O   1 
ATOM   2367 C CB  . GLU   B 1 73  ? 1.79256   1.11809   -50.21954 1.000 52.64000  ? 287 GLU   B CB  1 
ATOM   2368 C CG  . GLU   B 1 73  ? 1.59923   0.28615   -51.48253 1.000 56.28000  ? 287 GLU   B CG  1 
ATOM   2369 C CD  . GLU   B 1 73  ? 0.14308   0.32409   -51.96708 1.000 65.12000  ? 287 GLU   B CD  1 
ATOM   2370 O OE1 . GLU   B 1 73  ? -0.71672  0.79600   -51.19279 1.000 60.66000  ? 287 GLU   B OE1 1 
ATOM   2371 O OE2 . GLU   B 1 73  ? -0.15024  -0.12486  -53.10302 1.000 61.50000  ? 287 GLU   B OE2 1 
ATOM   2372 N N   . LYS   B 1 74  ? 2.49244   1.78295   -47.18471 1.000 53.08000  ? 288 LYS   B N   1 
ATOM   2373 C CA  . LYS   B 1 74  ? 2.82073   2.66991   -46.07376 1.000 56.68000  ? 288 LYS   B CA  1 
ATOM   2374 C C   . LYS   B 1 74  ? 4.22991   2.37796   -45.54820 1.000 61.75000  ? 288 LYS   B C   1 
ATOM   2375 O O   . LYS   B 1 74  ? 4.93299   3.28997   -45.08837 1.000 55.68000  ? 288 LYS   B O   1 
ATOM   2376 C CB  . LYS   B 1 74  ? 1.77608   2.53078   -44.95745 1.000 51.28000  ? 288 LYS   B CB  1 
ATOM   2377 C CG  . LYS   B 1 74  ? 2.27248   2.96673   -43.56158 1.000 57.77000  ? 288 LYS   B CG  1 
ATOM   2378 C CD  . LYS   B 1 74  ? 1.17180   3.00560   -42.47624 1.000 62.87000  ? 288 LYS   B CD  1 
ATOM   2379 C CE  . LYS   B 1 74  ? 1.68017   3.62956   -41.15636 1.000 68.39000  ? 288 LYS   B CE  1 
ATOM   2380 N NZ  . LYS   B 1 74  ? 3.15327   3.36263   -40.88182 1.000 68.12000  ? 288 LYS   B NZ  1 
ATOM   2381 N N   . GLY   B 1 75  ? 4.66595   1.12199   -45.64141 1.000 55.56000  ? 289 GLY   B N   1 
ATOM   2382 C CA  . GLY   B 1 75  ? 5.96712   0.72804   -45.17783 1.000 51.11000  ? 289 GLY   B CA  1 
ATOM   2383 C C   . GLY   B 1 75  ? 6.04157   0.75896   -43.67285 1.000 55.71000  ? 289 GLY   B C   1 
ATOM   2384 O O   . GLY   B 1 75  ? 5.02477   0.88986   -42.97853 1.000 66.26000  ? 289 GLY   B O   1 
ATOM   2385 N N   . PRO   B 1 76  ? 7.25174   0.62399   -43.13222 1.000 50.89000  ? 290 PRO   B N   1 
ATOM   2386 C CA  . PRO   B 1 76  ? 8.53055   0.40311   -43.80462 1.000 52.31000  ? 290 PRO   B CA  1 
ATOM   2387 C C   . PRO   B 1 76  ? 8.64149   -1.03886  -44.27074 1.000 54.72000  ? 290 PRO   B C   1 
ATOM   2388 O O   . PRO   B 1 76  ? 8.07274   -1.92793  -43.63162 1.000 57.71000  ? 290 PRO   B O   1 
ATOM   2389 C CB  . PRO   B 1 76  ? 9.54186   0.73210   -42.71091 1.000 48.58000  ? 290 PRO   B CB  1 
ATOM   2390 C CG  . PRO   B 1 76  ? 8.86426   0.24699   -41.48873 1.000 51.70000  ? 290 PRO   B CG  1 
ATOM   2391 C CD  . PRO   B 1 76  ? 7.40119   0.53192   -41.67527 1.000 50.43000  ? 290 PRO   B CD  1 
ATOM   2392 N N   . PRO   B 1 77  ? 9.34417   -1.29775  -45.37797 1.000 49.42000  ? 291 PRO   B N   1 
ATOM   2393 C CA  . PRO   B 1 77  ? 9.38210   -2.67472  -45.89806 1.000 54.45000  ? 291 PRO   B CA  1 
ATOM   2394 C C   . PRO   B 1 77  ? 10.13243  -3.62773  -44.99134 1.000 52.16000  ? 291 PRO   B C   1 
ATOM   2395 O O   . PRO   B 1 77  ? 9.79851   -4.82075  -44.93731 1.000 51.90000  ? 291 PRO   B O   1 
ATOM   2396 C CB  . PRO   B 1 77  ? 10.07867  -2.51660  -47.26226 1.000 46.26000  ? 291 PRO   B CB  1 
ATOM   2397 C CG  . PRO   B 1 77  ? 9.83748   -1.08260  -47.62811 1.000 44.81000  ? 291 PRO   B CG  1 
ATOM   2398 C CD  . PRO   B 1 77  ? 9.93483   -0.34166  -46.32909 1.000 49.36000  ? 291 PRO   B CD  1 
ATOM   2399 N N   . ASN   B 1 78  ? 11.13362  -3.13671  -44.26162 1.000 49.22000  ? 292 ASN   B N   1 
ATOM   2400 C CA  . ASN   B 1 78  ? 11.95692  -4.00571  -43.42792 1.000 52.69000  ? 292 ASN   B CA  1 
ATOM   2401 C C   . ASN   B 1 78  ? 11.17432  -4.52183  -42.22671 1.000 51.67000  ? 292 ASN   B C   1 
ATOM   2402 O O   . ASN   B 1 78  ? 11.73762  -5.20985  -41.36892 1.000 51.49000  ? 292 ASN   B O   1 
ATOM   2403 C CB  . ASN   B 1 78  ? 13.22103  -3.28767  -42.94126 1.000 51.12000  ? 292 ASN   B CB  1 
ATOM   2404 C CG  . ASN   B 1 78  ? 12.91520  -2.02973  -42.13810 1.000 52.90000  ? 292 ASN   B CG  1 
ATOM   2405 O OD1 . ASN   B 1 78  ? 11.75223  -1.63681  -41.95772 1.000 56.50000  ? 292 ASN   B OD1 1 
ATOM   2406 N ND2 . ASN   B 1 78  ? 13.96232  -1.40870  -41.61638 1.000 57.94000  ? 292 ASN   B ND2 1 
ATOM   2407 N N   . ALA   B 1 79  ? 9.89032   -4.16791  -42.14030 1.000 48.19000  ? 293 ALA   B N   1 
ATOM   2408 C CA  . ALA   B 1 79  ? 9.01768   -4.62002  -41.06806 1.000 47.48000  ? 293 ALA   B CA  1 
ATOM   2409 C C   . ALA   B 1 79  ? 8.19964   -5.84705  -41.43389 1.000 48.04000  ? 293 ALA   B C   1 
ATOM   2410 O O   . ALA   B 1 79  ? 7.64094   -6.48913  -40.54275 1.000 46.43000  ? 293 ALA   B O   1 
ATOM   2411 C CB  . ALA   B 1 79  ? 8.06274   -3.49810  -40.65771 1.000 44.46000  ? 293 ALA   B CB  1 
ATOM   2412 N N   . PHE   B 1 80  ? 8.11727   -6.19698  -42.71288 1.000 52.48000  ? 294 PHE   B N   1 
ATOM   2413 C CA  . PHE   B 1 80  ? 7.17019   -7.20801  -43.14765 1.000 49.01000  ? 294 PHE   B CA  1 
ATOM   2414 C C   . PHE   B 1 80  ? 7.86523   -8.55696  -43.28494 1.000 46.14000  ? 294 PHE   B C   1 
ATOM   2415 O O   . PHE   B 1 80  ? 8.89904   -8.67886  -43.94926 1.000 44.10000  ? 294 PHE   B O   1 
ATOM   2416 C CB  . PHE   B 1 80  ? 6.49377   -6.78297  -44.45242 1.000 47.18000  ? 294 PHE   B CB  1 
ATOM   2417 C CG  . PHE   B 1 80  ? 5.59775   -5.57803  -44.30108 1.000 45.95000  ? 294 PHE   B CG  1 
ATOM   2418 C CD1 . PHE   B 1 80  ? 6.13773   -4.31101  -44.12717 1.000 47.79000  ? 294 PHE   B CD1 1 
ATOM   2419 C CD2 . PHE   B 1 80  ? 4.22174   -5.70411  -44.34267 1.000 52.57000  ? 294 PHE   B CD2 1 
ATOM   2420 C CE1 . PHE   B 1 80  ? 5.32471   -3.19707  -43.98486 1.000 50.07000  ? 294 PHE   B CE1 1 
ATOM   2421 C CE2 . PHE   B 1 80  ? 3.40072   -4.58417  -44.20435 1.000 52.29000  ? 294 PHE   B CE2 1 
ATOM   2422 C CZ  . PHE   B 1 80  ? 3.96371   -3.33615  -44.01245 1.000 51.53000  ? 294 PHE   B CZ  1 
ATOM   2423 N N   . PHE   B 1 81  ? 7.27748   -9.55803  -42.64382 1.000 44.80000  ? 295 PHE   B N   1 
ATOM   2424 C CA  . PHE   B 1 81  ? 7.81760   -10.90001 -42.52606 1.000 42.93000  ? 295 PHE   B CA  1 
ATOM   2425 C C   . PHE   B 1 81  ? 6.70657   -11.90306 -42.81078 1.000 44.40000  ? 295 PHE   B C   1 
ATOM   2426 O O   . PHE   B 1 81  ? 5.52363   -11.64014 -42.56341 1.000 43.70000  ? 295 PHE   B O   1 
ATOM   2427 C CB  . PHE   B 1 81  ? 8.38804   -11.11406 -41.10525 1.000 43.95000  ? 295 PHE   B CB  1 
ATOM   2428 C CG  . PHE   B 1 81  ? 9.64607   -10.35100 -40.86358 1.000 46.91000  ? 295 PHE   B CG  1 
ATOM   2429 C CD1 . PHE   B 1 81  ? 9.59512   -9.03703  -40.43749 1.000 45.55000  ? 295 PHE   B CD1 1 
ATOM   2430 C CD2 . PHE   B 1 81  ? 10.88302  -10.91891 -41.13599 1.000 44.66000  ? 295 PHE   B CD2 1 
ATOM   2431 C CE1 . PHE   B 1 81  ? 10.76914  -8.30797  -40.26281 1.000 44.35000  ? 295 PHE   B CE1 1 
ATOM   2432 C CE2 . PHE   B 1 81  ? 12.03703  -10.19385 -40.96730 1.000 44.22000  ? 295 PHE   B CE2 1 
ATOM   2433 C CZ  . PHE   B 1 81  ? 11.97809  -8.88588  -40.52421 1.000 42.29000  ? 295 PHE   B CZ  1 
ATOM   2434 N N   . LEU   B 1 82  ? 7.09049   -13.07000 -43.30997 1.000 39.20000  ? 296 LEU   B N   1 
ATOM   2435 C CA  . LEU   B 1 82  ? 6.13549   -14.15805 -43.49374 1.000 36.42000  ? 296 LEU   B CA  1 
ATOM   2436 C C   . LEU   B 1 82  ? 6.62180   -15.36507 -42.70896 1.000 38.47000  ? 296 LEU   B C   1 
ATOM   2437 O O   . LEU   B 1 82  ? 7.81982   -15.66500 -42.70934 1.000 40.51000  ? 296 LEU   B O   1 
ATOM   2438 C CB  . LEU   B 1 82  ? 5.96106   -14.49397 -44.97570 1.000 40.45000  ? 296 LEU   B CB  1 
ATOM   2439 C CG  . LEU   B 1 82  ? 5.46903   -15.88098 -45.36064 1.000 38.14000  ? 296 LEU   B CG  1 
ATOM   2440 C CD1 . LEU   B 1 82  ? 4.01013   -16.01208 -45.05620 1.000 35.67000  ? 296 LEU   B CD1 1 
ATOM   2441 C CD2 . LEU   B 1 82  ? 5.77159   -16.13588 -46.84474 1.000 37.25000  ? 296 LEU   B CD2 1 
ATOM   2442 N N   . VAL   B 1 83  ? 5.70605   -16.03716 -42.01472 1.000 35.78000  ? 297 VAL   B N   1 
ATOM   2443 C CA  . VAL   B 1 83  ? 6.05037   -17.18519 -41.19289 1.000 34.13000  ? 297 VAL   B CA  1 
ATOM   2444 C C   . VAL   B 1 83  ? 5.06635   -18.30023 -41.48265 1.000 36.18000  ? 297 VAL   B C   1 
ATOM   2445 O O   . VAL   B 1 83  ? 3.86441   -18.14731 -41.24628 1.000 39.88000  ? 297 VAL   B O   1 
ATOM   2446 C CB  . VAL   B 1 83  ? 6.06281   -16.85027 -39.69287 1.000 37.85000  ? 297 VAL   B CB  1 
ATOM   2447 C CG1 . VAL   B 1 83  ? 6.00213   -18.14632 -38.87193 1.000 39.92000  ? 297 VAL   B CG1 1 
ATOM   2448 C CG2 . VAL   B 1 83  ? 7.33587   -16.05822 -39.33221 1.000 35.12000  ? 297 VAL   B CG2 1 
ATOM   2449 N N   . LYS   B 1 84  ? 5.56926   -19.42317 -41.97987 1.000 38.39000  ? 298 LYS   B N   1 
ATOM   2450 C CA  . LYS   B 1 84  ? 4.76027   -20.61821 -42.17169 1.000 41.03000  ? 298 LYS   B CA  1 
ATOM   2451 C C   . LYS   B 1 84  ? 4.99668   -21.58426 -41.01582 1.000 41.51000  ? 298 LYS   B C   1 
ATOM   2452 O O   . LYS   B 1 84  ? 6.14380   -21.88221 -40.66719 1.000 43.05000  ? 298 LYS   B O   1 
ATOM   2453 C CB  . LYS   B 1 84  ? 5.07491   -21.29811 -43.50383 1.000 43.44000  ? 298 LYS   B CB  1 
ATOM   2454 C CG  . LYS   B 1 84  ? 4.23691   -22.56115 -43.75165 1.000 45.35000  ? 298 LYS   B CG  1 
ATOM   2455 C CD  . LYS   B 1 84  ? 4.29749   -22.99906 -45.21069 1.000 44.99000  ? 298 LYS   B CD  1 
ATOM   2456 C CE  . LYS   B 1 84  ? 3.38247   -24.17810 -45.48548 1.000 43.70000  ? 298 LYS   B CE  1 
ATOM   2457 N NZ  . LYS   B 1 84  ? 3.49606   -24.56901 -46.90454 1.000 43.69000  ? 298 LYS   B NZ  1 
ATOM   2458 N N   . PHE   B 1 85  ? 3.91289   -22.06136 -40.42352 1.000 42.75000  ? 299 PHE   B N   1 
ATOM   2459 C CA  . PHE   B 1 85  ? 3.96428   -22.98742 -39.30059 1.000 47.24000  ? 299 PHE   B CA  1 
ATOM   2460 C C   . PHE   B 1 85  ? 3.52222   -24.36642 -39.75453 1.000 46.88000  ? 299 PHE   B C   1 
ATOM   2461 O O   . PHE   B 1 85  ? 2.63797   -24.49342 -40.60727 1.000 44.25000  ? 299 PHE   B O   1 
ATOM   2462 C CB  . PHE   B 1 85  ? 3.05460   -22.54154 -38.15829 1.000 40.53000  ? 299 PHE   B CB  1 
ATOM   2463 C CG  . PHE   B 1 85  ? 3.67682   -21.55155 -37.24042 1.000 39.21000  ? 299 PHE   B CG  1 
ATOM   2464 C CD1 . PHE   B 1 85  ? 4.80606   -21.87353 -36.52678 1.000 43.46000  ? 299 PHE   B CD1 1 
ATOM   2465 C CD2 . PHE   B 1 85  ? 3.10980   -20.29860 -37.06617 1.000 40.80000  ? 299 PHE   B CD2 1 
ATOM   2466 C CE1 . PHE   B 1 85  ? 5.37728   -20.95955 -35.63590 1.000 43.47000  ? 299 PHE   B CE1 1 
ATOM   2467 C CE2 . PHE   B 1 85  ? 3.66501   -19.37662 -36.20029 1.000 37.54000  ? 299 PHE   B CE2 1 
ATOM   2468 C CZ  . PHE   B 1 85  ? 4.79626   -19.71259 -35.47065 1.000 44.69000  ? 299 PHE   B CZ  1 
ATOM   2469 N N   . TRP   B 1 86  ? 4.14846   -25.39241 -39.18378 1.000 48.03000  ? 300 TRP   B N   1 
ATOM   2470 C CA  . TRP   B 1 86  ? 3.67150   -26.76744 -39.30172 1.000 48.76000  ? 300 TRP   B CA  1 
ATOM   2471 C C   . TRP   B 1 86  ? 3.10394   -27.14155 -37.93657 1.000 49.08000  ? 300 TRP   B C   1 
ATOM   2472 O O   . TRP   B 1 86  ? 3.85824   -27.43356 -37.00481 1.000 49.78000  ? 300 TRP   B O   1 
ATOM   2473 C CB  . TRP   B 1 86  ? 4.78542   -27.70934 -39.75811 1.000 47.38000  ? 300 TRP   B CB  1 
ATOM   2474 C CG  . TRP   B 1 86  ? 4.90897   -27.83125 -41.24516 1.000 47.75000  ? 300 TRP   B CG  1 
ATOM   2475 C CD1 . TRP   B 1 86  ? 4.38879   -28.82424 -42.02706 1.000 46.35000  ? 300 TRP   B CD1 1 
ATOM   2476 C CD2 . TRP   B 1 86  ? 5.59565   -26.93816 -42.14231 1.000 48.40000  ? 300 TRP   B CD2 1 
ATOM   2477 N NE1 . TRP   B 1 86  ? 4.71138   -28.60914 -43.34414 1.000 40.52000  ? 300 TRP   B NE1 1 
ATOM   2478 C CE2 . TRP   B 1 86  ? 5.44928   -27.46009 -43.44330 1.000 43.89000  ? 300 TRP   B CE2 1 
ATOM   2479 C CE3 . TRP   B 1 86  ? 6.32463   -25.75613 -41.97147 1.000 49.04000  ? 300 TRP   B CE3 1 
ATOM   2480 C CZ2 . TRP   B 1 86  ? 6.00391   -26.84400 -44.56443 1.000 47.07000  ? 300 TRP   B CZ2 1 
ATOM   2481 C CZ3 . TRP   B 1 86  ? 6.86526   -25.13903 -43.09059 1.000 47.10000  ? 300 TRP   B CZ3 1 
ATOM   2482 C CH2 . TRP   B 1 86  ? 6.69990   -25.68797 -44.37058 1.000 47.74000  ? 300 TRP   B CH2 1 
ATOM   2483 N N   . ALA   B 1 87  ? 1.77397   -27.11563 -37.82216 1.000 51.75000  ? 301 ALA   B N   1 
ATOM   2484 C CA  . ALA   B 1 87  ? 1.11837   -27.25074 -36.52397 1.000 52.28000  ? 301 ALA   B CA  1 
ATOM   2485 C C   . ALA   B 1 87  ? 1.22162   -28.66377 -35.97408 1.000 51.11000  ? 301 ALA   B C   1 
ATOM   2486 O O   . ALA   B 1 87  ? 1.03146   -29.65074 -36.68608 1.000 51.26000  ? 301 ALA   B O   1 
ATOM   2487 C CB  . ALA   B 1 87  ? -0.34568  -26.85482 -36.62050 1.000 47.79000  ? 301 ALA   B CB  1 
ATOM   2488 N N   . ASP   B 1 88  ? 1.55102   -28.74583 -34.68919 1.000 60.75000  ? 302 ASP   B N   1 
ATOM   2489 C CA  . ASP   B 1 88  ? 1.52732   -29.99487 -33.93225 1.000 62.82000  ? 302 ASP   B CA  1 
ATOM   2490 C C   . ASP   B 1 88  ? 0.12351   -30.16599 -33.35084 1.000 60.36000  ? 302 ASP   B C   1 
ATOM   2491 O O   . ASP   B 1 88  ? -0.28527  -29.40906 -32.46367 1.000 53.33000  ? 302 ASP   B O   1 
ATOM   2492 C CB  . ASP   B 1 88  ? 2.60565   -29.97087 -32.84658 1.000 51.64000  ? 302 ASP   B CB  1 
ATOM   2493 C CG  . ASP   B 1 88  ? 2.71895   -31.28791 -32.10569 1.000 61.93000  ? 302 ASP   B CG  1 
ATOM   2494 O OD1 . ASP   B 1 88  ? 1.85593   -32.17294 -32.33048 1.000 67.35000  ? 302 ASP   B OD1 1 
ATOM   2495 O OD2 . ASP   B 1 88  ? 3.68820   -31.45490 -31.32499 1.000 54.68000  ? 302 ASP   B OD2 1 
ATOM   2496 N N   . LEU   B 1 89  ? -0.63260  -31.13300 -33.87866 1.000 60.38000  ? 303 LEU   B N   1 
ATOM   2497 C CA  . LEU   B 1 89  ? -1.99044  -31.38811 -33.41026 1.000 65.02000  ? 303 LEU   B CA  1 
ATOM   2498 C C   . LEU   B 1 89  ? -2.11915  -32.73515 -32.70430 1.000 70.62000  ? 303 LEU   B C   1 
ATOM   2499 O O   . LEU   B 1 89  ? -3.22708  -33.26923 -32.58900 1.000 68.19000  ? 303 LEU   B O   1 
ATOM   2500 C CB  . LEU   B 1 89  ? -2.98480  -31.28310 -34.56796 1.000 67.57000  ? 303 LEU   B CB  1 
ATOM   2501 C CG  . LEU   B 1 89  ? -3.57496  -29.89112 -34.82670 1.000 58.42000  ? 303 LEU   B CG  1 
ATOM   2502 C CD1 . LEU   B 1 89  ? -4.57829  -29.95111 -35.94840 1.000 59.84000  ? 303 LEU   B CD1 1 
ATOM   2503 C CD2 . LEU   B 1 89  ? -4.24560  -29.36523 -33.56346 1.000 56.47000  ? 303 LEU   B CD2 1 
ATOM   2504 N N   . ASN   B 1 90  ? -0.99897  -33.28212 -32.22068 1.000 77.18000  ? 304 ASN   B N   1 
ATOM   2505 C CA  . ASN   B 1 90  ? -0.98967  -34.53916 -31.47975 1.000 77.55000  ? 304 ASN   B CA  1 
ATOM   2506 C C   . ASN   B 1 90  ? -1.53325  -34.34327 -30.07457 1.000 82.14000  ? 304 ASN   B C   1 
ATOM   2507 O O   . ASN   B 1 90  ? -1.10409  -33.43629 -29.35565 1.000 80.82000  ? 304 ASN   B O   1 
ATOM   2508 C CB  . ASN   B 1 90  ? 0.43339   -35.08008 -31.39821 1.000 73.88000  ? 304 ASN   B CB  1 
ATOM   2509 C CG  . ASN   B 1 90  ? 0.72513   -36.11200 -32.44936 1.000 83.12000  ? 304 ASN   B CG  1 
ATOM   2510 O OD1 . ASN   B 1 90  ? 1.65388   -35.95290 -33.24764 1.000 83.16000  ? 304 ASN   B OD1 1 
ATOM   2511 N ND2 . ASN   B 1 90  ? -0.04381  -37.19905 -32.44319 1.000 90.00000  ? 304 ASN   B ND2 1 
ATOM   2512 N N   . SER   B 1 91  ? -2.45408  -35.21635 -29.66635 1.000 88.82000  ? 305 SER   B N   1 
ATOM   2513 C CA  . SER   B 1 91  ? -2.99067  -35.16246 -28.30618 1.000 98.27000  ? 305 SER   B CA  1 
ATOM   2514 C C   . SER   B 1 91  ? -2.03134  -35.88846 -27.35951 1.000 101.42000 ? 305 SER   B C   1 
ATOM   2515 O O   . SER   B 1 91  ? -2.29113  -36.99050 -26.86950 1.000 101.69000 ? 305 SER   B O   1 
ATOM   2516 C CB  . SER   B 1 91  ? -4.39662  -35.75254 -28.24779 1.000 99.62000  ? 305 SER   B CB  1 
ATOM   2517 O OG  . SER   B 1 91  ? -4.87721  -35.82165 -26.90864 1.000 102.98000 ? 305 SER   B OG  1 
ATOM   2518 N N   . THR   B 1 92  ? -0.88230  -35.24141 -27.10282 1.000 101.43000 ? 306 THR   B N   1 
ATOM   2519 C CA  . THR   B 1 92  ? -0.01994  -35.71042 -26.01911 1.000 104.30000 ? 306 THR   B CA  1 
ATOM   2520 C C   . THR   B 1 92  ? -0.82955  -35.80154 -24.73587 1.000 106.51000 ? 306 THR   B C   1 
ATOM   2521 O O   . THR   B 1 92  ? -0.57324  -36.66057 -23.88200 1.000 108.75000 ? 306 THR   B O   1 
ATOM   2522 C CB  . THR   B 1 92  ? 1.19207   -34.78436 -25.80743 1.000 102.65000 ? 306 THR   B CB  1 
ATOM   2523 O OG1 . THR   B 1 92  ? 0.78020   -33.57442 -25.14723 1.000 98.68000  ? 306 THR   B OG1 1 
ATOM   2524 C CG2 . THR   B 1 92  ? 1.87965   -34.43124 -27.13062 1.000 91.58000  ? 306 THR   B CG2 1 
ATOM   2525 N N   . ILE   B 1 93  ? -1.83456  -34.93261 -24.61052 1.000 106.36000 ? 307 ILE   B N   1 
ATOM   2526 C CA  . ILE   B 1 93  ? -2.73222  -34.86872 -23.46924 1.000 105.19000 ? 307 ILE   B CA  1 
ATOM   2527 C C   . ILE   B 1 93  ? -4.17437  -34.81078 -23.95780 1.000 108.15000 ? 307 ILE   B C   1 
ATOM   2528 O O   . ILE   B 1 93  ? -4.46073  -34.28773 -25.04468 1.000 99.95000  ? 307 ILE   B O   1 
ATOM   2529 C CB  . ILE   B 1 93  ? -2.41802  -33.64476 -22.59126 1.000 98.65000  ? 307 ILE   B CB  1 
ATOM   2530 C CG1 . ILE   B 1 93  ? -2.16537  -32.43169 -23.50727 1.000 94.62000  ? 307 ILE   B CG1 1 
ATOM   2531 C CG2 . ILE   B 1 93  ? -1.27671  -33.98274 -21.64663 1.000 97.96000  ? 307 ILE   B CG2 1 
ATOM   2532 C CD1 . ILE   B 1 93  ? -1.66324  -31.16470 -22.83035 1.000 82.98000  ? 307 ILE   B CD1 1 
ATOM   2533 N N   . GLN   B 1 94  ? -5.07709  -35.36088 -23.14256 1.000 113.45000 ? 308 GLN   B N   1 
ATOM   2534 C CA  . GLN   B 1 94  ? -6.51115  -35.16095 -23.30711 1.000 105.10000 ? 308 GLN   B CA  1 
ATOM   2535 C C   . GLN   B 1 94  ? -6.88213  -33.72300 -22.95691 1.000 101.09000 ? 308 GLN   B C   1 
ATOM   2536 O O   . GLN   B 1 94  ? -6.28089  -33.10901 -22.07006 1.000 98.02000  ? 308 GLN   B O   1 
ATOM   2537 C CB  . GLN   B 1 94  ? -7.27182  -36.14705 -22.40893 1.000 106.09000 ? 308 GLN   B CB  1 
ATOM   2538 C CG  . GLN   B 1 94  ? -7.62141  -35.67015 -20.95380 1.000 112.01000 ? 308 GLN   B CG  1 
ATOM   2539 C CD  . GLN   B 1 94  ? -6.41715  -35.35614 -20.03715 1.000 112.43000 ? 308 GLN   B CD  1 
ATOM   2540 O OE1 . GLN   B 1 94  ? -5.25626  -35.45605 -20.44651 1.000 111.48000 ? 308 GLN   B OE1 1 
ATOM   2541 N NE2 . GLN   B 1 94  ? -6.70879  -34.98823 -18.78204 1.000 94.20000  ? 308 GLN   B NE2 1 
ATOM   2542 N N   . GLU   B 1 95  ? -7.86337  -33.16301 -23.63558 1.000 96.97000  ? 309 GLU   B N   1 
ATOM   2543 C CA  . GLU   B 1 95  ? -8.28434  -31.83706 -23.28538 1.000 90.56000  ? 309 GLU   B CA  1 
ATOM   2544 C C   . GLU   B 1 95  ? -8.86091  -31.91517 -21.90721 1.000 96.74000  ? 309 GLU   B C   1 
ATOM   2545 O O   . GLU   B 1 95  ? -8.35766  -31.31820 -20.97133 1.000 90.44000  ? 309 GLU   B O   1 
ATOM   2546 C CB  . GLU   B 1 95  ? -9.33966  -31.35706 -24.25703 1.000 90.73000  ? 309 GLU   B CB  1 
ATOM   2547 C CG  . GLU   B 1 95  ? -9.93663  -30.01312 -23.90377 1.000 88.50000  ? 309 GLU   B CG  1 
ATOM   2548 C CD  . GLU   B 1 95  ? -10.97996 -29.56812 -24.90043 1.000 91.51000  ? 309 GLU   B CD  1 
ATOM   2549 O OE1 . GLU   B 1 95  ? -11.25920 -30.32908 -25.84739 1.000 90.05000  ? 309 GLU   B OE1 1 
ATOM   2550 O OE2 . GLU   B 1 95  ? -11.51998 -28.45616 -24.73820 1.000 94.34000  ? 309 GLU   B OE2 1 
ATOM   2551 N N   . GLY   B 1 96  ? -9.92283  -32.68624 -21.76793 1.000 100.03000 ? 310 GLY   B N   1 
ATOM   2552 C CA  . GLY   B 1 96  ? -10.58743 -32.77335 -20.49173 1.000 90.86000  ? 310 GLY   B CA  1 
ATOM   2553 C C   . GLY   B 1 96  ? -11.56742 -31.65342 -20.24437 1.000 87.37000  ? 310 GLY   B C   1 
ATOM   2554 O O   . GLY   B 1 96  ? -11.83374 -30.84039 -21.12024 1.000 88.33000  ? 310 GLY   B O   1 
ATOM   2555 N N   . PRO   B 1 97  ? -12.10506 -31.59653 -19.03520 1.000 84.37000  ? 311 PRO   B N   1 
ATOM   2556 C CA  . PRO   B 1 97  ? -13.10302 -30.58660 -18.71084 1.000 82.25000  ? 311 PRO   B CA  1 
ATOM   2557 C C   . PRO   B 1 97  ? -12.59513 -29.15657 -18.80791 1.000 81.97000  ? 311 PRO   B C   1 
ATOM   2558 O O   . PRO   B 1 97  ? -13.35832 -28.32059 -19.27263 1.000 85.81000  ? 311 PRO   B O   1 
ATOM   2559 C CB  . PRO   B 1 97  ? -13.42356 -30.89571 -17.24976 1.000 83.47000  ? 311 PRO   B CB  1 
ATOM   2560 C CG  . PRO   B 1 97  ? -12.28136 -31.70167 -16.73716 1.000 83.13000  ? 311 PRO   B CG  1 
ATOM   2561 C CD  . PRO   B 1 97  ? -11.82667 -32.49857 -17.90934 1.000 81.04000  ? 311 PRO   B CD  1 
ATOM   2562 N N   . GLY   B 1 98  ? -11.38102 -28.85952 -18.36227 1.000 75.94000  ? 312 GLY   B N   1 
ATOM   2563 C CA  . GLY   B 1 98  ? -10.92810 -27.48349 -18.39332 1.000 71.40000  ? 312 GLY   B CA  1 
ATOM   2564 C C   . GLY   B 1 98  ? -9.57129  -27.17538 -18.94872 1.000 70.68000  ? 312 GLY   B C   1 
ATOM   2565 O O   . GLY   B 1 98  ? -8.67809  -26.78337 -18.21597 1.000 62.79000  ? 312 GLY   B O   1 
ATOM   2566 N N   . ALA   B 1 99  ? -9.40868  -27.34430 -20.24378 1.000 69.07000  ? 313 ALA   B N   1 
ATOM   2567 C CA  . ALA   B 1 99  ? -8.17389  -26.96619 -20.89013 1.000 61.40000  ? 313 ALA   B CA  1 
ATOM   2568 C C   . ALA   B 1 99  ? -8.09104  -25.47517 -21.08307 1.000 56.27000  ? 313 ALA   B C   1 
ATOM   2569 O O   . ALA   B 1 99  ? -9.10810  -24.81623 -21.16072 1.000 57.78000  ? 313 ALA   B O   1 
ATOM   2570 C CB  . ALA   B 1 99  ? -8.04525  -27.67811 -22.20621 1.000 62.37000  ? 313 ALA   B CB  1 
ATOM   2571 N N   . PHE   B 1 100 ? -6.88810  -24.94210 -21.18140 1.000 56.75000  ? 314 PHE   B N   1 
ATOM   2572 C CA  . PHE   B 1 100 ? -6.72427  -23.52907 -21.46837 1.000 56.44000  ? 314 PHE   B CA  1 
ATOM   2573 C C   . PHE   B 1 100 ? -6.07869  -23.34496 -22.80556 1.000 52.74000  ? 314 PHE   B C   1 
ATOM   2574 O O   . PHE   B 1 100 ? -5.05574  -23.94388 -23.08690 1.000 52.21000  ? 314 PHE   B O   1 
ATOM   2575 C CB  . PHE   B 1 100 ? -5.85999  -22.84708 -20.42060 1.000 56.64000  ? 314 PHE   B CB  1 
ATOM   2576 C CG  . PHE   B 1 100 ? -5.37419  -21.48503 -20.82366 1.000 57.69000  ? 314 PHE   B CG  1 
ATOM   2577 C CD1 . PHE   B 1 100 ? -6.22024  -20.39508 -20.77934 1.000 53.33000  ? 314 PHE   B CD1 1 
ATOM   2578 C CD2 . PHE   B 1 100 ? -4.06833  -21.29493 -21.23505 1.000 56.20000  ? 314 PHE   B CD2 1 
ATOM   2579 C CE1 . PHE   B 1 100 ? -5.77643  -19.14104 -21.14541 1.000 58.06000  ? 314 PHE   B CE1 1 
ATOM   2580 C CE2 . PHE   B 1 100 ? -3.61851  -20.04488 -21.60111 1.000 51.76000  ? 314 PHE   B CE2 1 
ATOM   2581 C CZ  . PHE   B 1 100 ? -4.47256  -18.96594 -21.55579 1.000 57.44000  ? 314 PHE   B CZ  1 
ATOM   2582 N N   . TYR   B 1 101 ? -6.68099  -22.50994 -23.63133 1.000 54.76000  ? 315 TYR   B N   1 
ATOM   2583 C CA  . TYR   B 1 101 ? -6.13840  -22.22784 -24.93948 1.000 49.35000  ? 315 TYR   B CA  1 
ATOM   2584 C C   . TYR   B 1 101 ? -5.59047  -20.83581 -24.90456 1.000 49.39000  ? 315 TYR   B C   1 
ATOM   2585 O O   . TYR   B 1 101 ? -6.30043  -19.89987 -24.59929 1.000 45.95000  ? 315 TYR   B O   1 
ATOM   2586 C CB  . TYR   B 1 101 ? -7.21471  -22.40184 -25.99316 1.000 47.62000  ? 315 TYR   B CB  1 
ATOM   2587 C CG  . TYR   B 1 101 ? -7.51872  -23.83884 -26.31915 1.000 53.52000  ? 315 TYR   B CG  1 
ATOM   2588 C CD1 . TYR   B 1 101 ? -8.47847  -24.54293 -25.61590 1.000 51.57000  ? 315 TYR   B CD1 1 
ATOM   2589 C CD2 . TYR   B 1 101 ? -6.84600  -24.48874 -27.33539 1.000 56.31000  ? 315 TYR   B CD2 1 
ATOM   2590 C CE1 . TYR   B 1 101 ? -8.75748  -25.85893 -25.91589 1.000 59.11000  ? 315 TYR   B CE1 1 
ATOM   2591 C CE2 . TYR   B 1 101 ? -7.11801  -25.80174 -27.64538 1.000 57.86000  ? 315 TYR   B CE2 1 
ATOM   2592 C CZ  . TYR   B 1 101 ? -8.07376  -26.48283 -26.93213 1.000 58.07000  ? 315 TYR   B CZ  1 
ATOM   2593 O OH  . TYR   B 1 101 ? -8.34077  -27.79083 -27.23913 1.000 62.38000  ? 315 TYR   B OH  1 
ATOM   2594 N N   . GLY   B 1 102 ? -4.31958  -20.68971 -25.23794 1.000 51.18000  ? 316 GLY   B N   1 
ATOM   2595 C CA  . GLY   B 1 102 ? -3.68761  -19.39669 -25.09106 1.000 47.00000  ? 316 GLY   B CA  1 
ATOM   2596 C C   . GLY   B 1 102 ? -2.52091  -19.17056 -26.01940 1.000 45.55000  ? 316 GLY   B C   1 
ATOM   2597 O O   . GLY   B 1 102 ? -1.98904  -20.09250 -26.64861 1.000 41.78000  ? 316 GLY   B O   1 
ATOM   2598 N N   . VAL   B 1 103 ? -2.12400  -17.90254 -26.07444 1.000 49.33000  ? 317 VAL   B N   1 
ATOM   2599 C CA  . VAL   B 1 103 ? -0.98826  -17.44743 -26.86676 1.000 48.64000  ? 317 VAL   B CA  1 
ATOM   2600 C C   . VAL   B 1 103 ? -0.07904  -16.60742 -25.97599 1.000 51.88000  ? 317 VAL   B C   1 
ATOM   2601 O O   . VAL   B 1 103 ? -0.55087  -15.73749 -25.23180 1.000 48.54000  ? 317 VAL   B O   1 
ATOM   2602 C CB  . VAL   B 1 103 ? -1.42169  -16.62838 -28.09958 1.000 46.63000  ? 317 VAL   B CB  1 
ATOM   2603 C CG1 . VAL   B 1 103 ? -0.23690  -15.83328 -28.65490 1.000 49.23000  ? 317 VAL   B CG1 1 
ATOM   2604 C CG2 . VAL   B 1 103 ? -2.01796  -17.53935 -29.17146 1.000 43.57000  ? 317 VAL   B CG2 1 
ATOM   2605 N N   . SER   B 1 104 ? 1.21995   -16.86434 -26.06040 1.000 51.74000  ? 318 SER   B N   1 
ATOM   2606 C CA  . SER   B 1 104 ? 2.22511   -16.06232 -25.38366 1.000 50.04000  ? 318 SER   B CA  1 
ATOM   2607 C C   . SER   B 1 104 ? 3.17876   -15.50421 -26.42992 1.000 49.30000  ? 318 SER   B C   1 
ATOM   2608 O O   . SER   B 1 104 ? 3.55151   -16.20713 -27.37307 1.000 52.69000  ? 318 SER   B O   1 
ATOM   2609 C CB  . SER   B 1 104 ? 2.97547   -16.90634 -24.35994 1.000 48.43000  ? 318 SER   B CB  1 
ATOM   2610 O OG  . SER   B 1 104 ? 2.17683   -17.13645 -23.20871 1.000 52.86000  ? 318 SER   B OG  1 
ATOM   2611 N N   . SER   B 1 105 ? 3.55273   -14.23919 -26.29096 1.000 45.90000  ? 319 SER   B N   1 
ATOM   2612 C CA  . SER   B 1 105 ? 4.54442   -13.69108 -27.20223 1.000 52.37000  ? 319 SER   B CA  1 
ATOM   2613 C C   . SER   B 1 105 ? 5.38458   -12.65708 -26.46842 1.000 52.26000  ? 319 SER   B C   1 
ATOM   2614 O O   . SER   B 1 105 ? 4.93284   -12.03516 -25.50425 1.000 49.38000  ? 319 SER   B O   1 
ATOM   2615 C CB  . SER   B 1 105 ? 3.90300   -13.09005 -28.47000 1.000 48.94000  ? 319 SER   B CB  1 
ATOM   2616 O OG  . SER   B 1 105 ? 2.86904   -12.17813 -28.15463 1.000 50.79000  ? 319 SER   B OG  1 
ATOM   2617 N N   . GLN   B 1 106 ? 6.61942   -12.48598 -26.94579 1.000 54.04000  ? 320 GLN   B N   1 
ATOM   2618 C CA  . GLN   B 1 106 ? 7.60156   -11.59696 -26.34104 1.000 50.42000  ? 320 GLN   B CA  1 
ATOM   2619 C C   . GLN   B 1 106 ? 8.29018   -10.79785 -27.43720 1.000 47.65000  ? 320 GLN   B C   1 
ATOM   2620 O O   . GLN   B 1 106 ? 8.63789   -11.34477 -28.49034 1.000 46.75000  ? 320 GLN   B O   1 
ATOM   2621 C CB  . GLN   B 1 106 ? 8.63385   -12.39394 -25.53539 1.000 52.41000  ? 320 GLN   B CB  1 
ATOM   2622 C CG  . GLN   B 1 106 ? 9.01722   -11.78200 -24.20648 1.000 58.59000  ? 320 GLN   B CG  1 
ATOM   2623 C CD  . GLN   B 1 106 ? 9.85053   -12.72200 -23.35178 1.000 63.18000  ? 320 GLN   B CD  1 
ATOM   2624 O OE1 . GLN   B 1 106 ? 11.05856  -12.51894 -23.20014 1.000 66.61000  ? 320 GLN   B OE1 1 
ATOM   2625 N NE2 . GLN   B 1 106 ? 9.21576   -13.75807 -22.79165 1.000 60.90000  ? 320 GLN   B NE2 1 
ATOM   2626 N N   . TYR   B 1 107 ? 8.47118   -9.49986  -27.19018 1.000 45.27000  ? 321 TYR   B N   1 
ATOM   2627 C CA  . TYR   B 1 107 ? 9.07183   -8.57577  -28.14831 1.000 49.36000  ? 321 TYR   B CA  1 
ATOM   2628 C C   . TYR   B 1 107 ? 10.08599  -7.67775  -27.43956 1.000 46.73000  ? 321 TYR   B C   1 
ATOM   2629 O O   . TYR   B 1 107 ? 9.98035   -7.42882  -26.23452 1.000 46.30000  ? 321 TYR   B O   1 
ATOM   2630 C CB  . TYR   B 1 107 ? 8.03857   -7.64979  -28.82494 1.000 42.36000  ? 321 TYR   B CB  1 
ATOM   2631 C CG  . TYR   B 1 107 ? 6.83943   -8.31182  -29.41361 1.000 49.30000  ? 321 TYR   B CG  1 
ATOM   2632 C CD1 . TYR   B 1 107 ? 5.78870   -8.77393  -28.61032 1.000 50.47000  ? 321 TYR   B CD1 1 
ATOM   2633 C CD2 . TYR   B 1 107 ? 6.75502   -8.50375  -30.79260 1.000 52.11000  ? 321 TYR   B CD2 1 
ATOM   2634 C CE1 . TYR   B 1 107 ? 4.68157   -9.39696  -29.17802 1.000 53.47000  ? 321 TYR   B CE1 1 
ATOM   2635 C CE2 . TYR   B 1 107 ? 5.66288   -9.11078  -31.36930 1.000 50.98000  ? 321 TYR   B CE2 1 
ATOM   2636 C CZ  . TYR   B 1 107 ? 4.62315   -9.56188  -30.57001 1.000 55.62000  ? 321 TYR   B CZ  1 
ATOM   2637 O OH  . TYR   B 1 107 ? 3.53600   -10.17191 -31.17572 1.000 51.67000  ? 321 TYR   B OH  1 
ATOM   2638 N N   . SER   B 1 108 ? 11.01973  -7.11565  -28.21481 1.000 43.18000  ? 322 SER   B N   1 
ATOM   2639 C CA  . SER   B 1 108 ? 12.00384  -6.19162  -27.66606 1.000 49.64000  ? 322 SER   B CA  1 
ATOM   2640 C C   . SER   B 1 108 ? 12.22849  -5.00156  -28.58706 1.000 48.75000  ? 322 SER   B C   1 
ATOM   2641 O O   . SER   B 1 108 ? 12.00013  -5.07150  -29.79399 1.000 50.68000  ? 322 SER   B O   1 
ATOM   2642 C CB  . SER   B 1 108 ? 13.35295  -6.87356  -27.42451 1.000 48.74000  ? 322 SER   B CB  1 
ATOM   2643 O OG  . SER   B 1 108 ? 14.00259  -7.09445  -28.65972 1.000 53.08000  ? 322 SER   B OG  1 
ATOM   2644 N N   . SER   B 1 109 ? 12.70761  -3.90956  -27.99614 1.000 53.07000  ? 323 SER   B N   1 
ATOM   2645 C CA  . SER   B 1 109 ? 13.11131  -2.72750  -28.74520 1.000 56.05000  ? 323 SER   B CA  1 
ATOM   2646 C C   . SER   B 1 109 ? 14.16050  -1.95148  -27.95347 1.000 56.31000  ? 323 SER   B C   1 
ATOM   2647 O O   . SER   B 1 109 ? 14.19988  -2.00655  -26.72249 1.000 55.70000  ? 323 SER   B O   1 
ATOM   2648 C CB  . SER   B 1 109 ? 11.89916  -1.83955  -29.07678 1.000 52.55000  ? 323 SER   B CB  1 
ATOM   2649 O OG  . SER   B 1 109 ? 11.31748  -1.30165  -27.89757 1.000 54.65000  ? 323 SER   B OG  1 
ATOM   2650 N N   . ALA   B 1 110 ? 15.04324  -1.25839  -28.67870 1.000 55.30000  ? 324 ALA   B N   1 
ATOM   2651 C CA  . ALA   B 1 110 ? 15.91539  -0.29037  -28.02591 1.000 54.36000  ? 324 ALA   B CA  1 
ATOM   2652 C C   . ALA   B 1 110 ? 15.11247  0.89555   -27.50559 1.000 54.06000  ? 324 ALA   B C   1 
ATOM   2653 O O   . ALA   B 1 110 ? 15.50373  1.54652   -26.53668 1.000 49.67000  ? 324 ALA   B O   1 
ATOM   2654 C CB  . ALA   B 1 110 ? 16.99606  0.17275   -29.00121 1.000 54.08000  ? 324 ALA   B CB  1 
ATOM   2655 N N   . ASP   B 1 111 ? 13.97827  1.16552   -28.13423 1.000 62.73000  ? 325 ASP   B N   1 
ATOM   2656 C CA  . ASP   B 1 111 ? 13.06928  2.26545   -27.87790 1.000 58.86000  ? 325 ASP   B CA  1 
ATOM   2657 C C   . ASP   B 1 111 ? 12.15466  1.93033   -26.69264 1.000 59.94000  ? 325 ASP   B C   1 
ATOM   2658 O O   . ASP   B 1 111 ? 12.01385  0.76630   -26.31066 1.000 59.31000  ? 325 ASP   B O   1 
ATOM   2659 C CB  . ASP   B 1 111 ? 12.24188  2.49848   -29.14663 1.000 54.10000  ? 325 ASP   B CB  1 
ATOM   2660 C CG  . ASP   B 1 111 ? 11.91573  3.93347   -29.36445 1.000 66.15000  ? 325 ASP   B CG  1 
ATOM   2661 O OD1 . ASP   B 1 111 ? 12.46791  4.77846   -28.62657 1.000 64.79000  ? 325 ASP   B OD1 1 
ATOM   2662 O OD2 . ASP   B 1 111 ? 11.13243  4.21548   -30.29419 1.000 77.94000  ? 325 ASP   B OD2 1 
ATOM   2663 N N   . SER   B 1 112 ? 11.49278  2.95126   -26.11838 1.000 57.06000  ? 326 SER   B N   1 
ATOM   2664 C CA  . SER   B 1 112 ? 10.40608  2.70614   -25.16106 1.000 51.73000  ? 326 SER   B CA  1 
ATOM   2665 C C   . SER   B 1 112 ? 9.08688   3.19610   -25.73663 1.000 54.18000  ? 326 SER   B C   1 
ATOM   2666 O O   . SER   B 1 112 ? 8.85678   4.40909   -25.82649 1.000 54.04000  ? 326 SER   B O   1 
ATOM   2667 C CB  . SER   B 1 112 ? 10.64445  3.38108   -23.82009 1.000 51.27000  ? 326 SER   B CB  1 
ATOM   2668 O OG  . SER   B 1 112 ? 9.56273   3.08796   -22.95078 1.000 51.33000  ? 326 SER   B OG  1 
ATOM   2669 N N   . MET   B 1 113 ? 8.19784   2.25306   -26.05442 1.000 46.91000  ? 327 MET   B N   1 
ATOM   2670 C CA  . MET   B 1 113 ? 6.94961   2.55603   -26.73602 1.000 52.81000  ? 327 MET   B CA  1 
ATOM   2671 C C   . MET   B 1 113 ? 5.78187   1.90792   -26.00570 1.000 55.35000  ? 327 MET   B C   1 
ATOM   2672 O O   . MET   B 1 113 ? 5.94919   1.05888   -25.12280 1.000 55.74000  ? 327 MET   B O   1 
ATOM   2673 C CB  . MET   B 1 113 ? 6.98720   2.07312   -28.19206 1.000 54.33000  ? 327 MET   B CB  1 
ATOM   2674 C CG  . MET   B 1 113 ? 8.40106   1.83123   -28.68050 1.000 60.20000  ? 327 MET   B CG  1 
ATOM   2675 S SD  . MET   B 1 113 ? 8.51760   1.19433   -30.34157 1.000 51.01000  ? 327 MET   B SD  1 
ATOM   2676 C CE  . MET   B 1 113 ? 7.95326   2.65734   -31.16832 1.000 65.76000  ? 327 MET   B CE  1 
ATOM   2677 N N   . THR   B 1 114 ? 4.58173   2.33887   -26.38031 1.000 50.96000  ? 328 THR   B N   1 
ATOM   2678 C CA  . THR   B 1 114 ? 3.35687   1.61778   -26.07698 1.000 50.71000  ? 328 THR   B CA  1 
ATOM   2679 C C   . THR   B 1 114 ? 2.91552   0.93183   -27.35989 1.000 50.96000  ? 328 THR   B C   1 
ATOM   2680 O O   . THR   B 1 114 ? 2.58618   1.60587   -28.33575 1.000 50.78000  ? 328 THR   B O   1 
ATOM   2681 C CB  . THR   B 1 114 ? 2.27696   2.57069   -25.57860 1.000 52.86000  ? 328 THR   B CB  1 
ATOM   2682 O OG1 . THR   B 1 114 ? 2.73728   3.22565   -24.39070 1.000 58.62000  ? 328 THR   B OG1 1 
ATOM   2683 C CG2 . THR   B 1 114 ? 0.98909   1.82160   -25.30525 1.000 58.29000  ? 328 THR   B CG2 1 
ATOM   2684 N N   . ILE   B 1 115 ? 2.93458   -0.37817  -27.38597 1.000 48.38000  ? 329 ILE   B N   1 
ATOM   2685 C CA  . ILE   B 1 115 ? 2.65024   -1.03911  -28.65092 1.000 49.89000  ? 329 ILE   B CA  1 
ATOM   2686 C C   . ILE   B 1 115 ? 1.20927   -1.54419  -28.65751 1.000 54.67000  ? 329 ILE   B C   1 
ATOM   2687 O O   . ILE   B 1 115 ? 0.61460   -1.86329  -27.61135 1.000 50.75000  ? 329 ILE   B O   1 
ATOM   2688 C CB  . ILE   B 1 115 ? 3.65821   -2.16603  -28.96429 1.000 47.30000  ? 329 ILE   B CB  1 
ATOM   2689 C CG1 . ILE   B 1 115 ? 3.49956   -3.35510  -28.02331 1.000 47.86000  ? 329 ILE   B CG1 1 
ATOM   2690 C CG2 . ILE   B 1 115 ? 5.10218   -1.62695  -28.95270 1.000 43.45000  ? 329 ILE   B CG2 1 
ATOM   2691 C CD1 . ILE   B 1 115 ? 4.24548   -4.58403  -28.52561 1.000 43.52000  ? 329 ILE   B CD1 1 
ATOM   2692 N N   . SER   B 1 116 ? 0.62590   -1.55116  -29.85734 1.000 50.38000  ? 330 SER   B N   1 
ATOM   2693 C CA  . SER   B 1 116 ? -0.68714  -2.12622  -30.12297 1.000 49.01000  ? 330 SER   B CA  1 
ATOM   2694 C C   . SER   B 1 116 ? -0.53939  -3.24215  -31.14708 1.000 44.81000  ? 330 SER   B C   1 
ATOM   2695 O O   . SER   B 1 116 ? 0.02227   -3.02906  -32.22624 1.000 48.13000  ? 330 SER   B O   1 
ATOM   2696 C CB  . SER   B 1 116 ? -1.67036  -1.07125  -30.62761 1.000 53.47000  ? 330 SER   B CB  1 
ATOM   2697 O OG  . SER   B 1 116 ? -2.78452  -1.68528  -31.26131 1.000 57.31000  ? 330 SER   B OG  1 
ATOM   2698 N N   . VAL   B 1 117 ? -1.04122  -4.42420  -30.80500 1.000 44.97000  ? 331 VAL   B N   1 
ATOM   2699 C CA  . VAL   B 1 117 ? -0.89039  -5.63415  -31.60911 1.000 44.73000  ? 331 VAL   B CA  1 
ATOM   2700 C C   . VAL   B 1 117 ? -2.26153  -6.03920  -32.14072 1.000 46.57000  ? 331 VAL   B C   1 
ATOM   2701 O O   . VAL   B 1 117 ? -3.18128  -6.35029  -31.37146 1.000 52.50000  ? 331 VAL   B O   1 
ATOM   2702 C CB  . VAL   B 1 117 ? -0.24008  -6.76816  -30.79537 1.000 40.63000  ? 331 VAL   B CB  1 
ATOM   2703 C CG1 . VAL   B 1 117 ? -0.07426  -8.02910  -31.63050 1.000 34.72000  ? 331 VAL   B CG1 1 
ATOM   2704 C CG2 . VAL   B 1 117 ? 1.11405   -6.30511  -30.28676 1.000 44.35000  ? 331 VAL   B CG2 1 
ATOM   2705 N N   . SER   B 1 118 ? -2.39593  -6.03613  -33.45468 1.000 46.93000  ? 332 SER   B N   1 
ATOM   2706 C CA  . SER   B 1 118 ? -3.60911  -6.43716  -34.13633 1.000 41.75000  ? 332 SER   B CA  1 
ATOM   2707 C C   . SER   B 1 118 ? -3.38721  -7.81911  -34.71748 1.000 42.72000  ? 332 SER   B C   1 
ATOM   2708 O O   . SER   B 1 118 ? -2.49045  -8.00301  -35.54576 1.000 45.48000  ? 332 SER   B O   1 
ATOM   2709 C CB  . SER   B 1 118 ? -3.95451  -5.44611  -35.24117 1.000 45.43000  ? 332 SER   B CB  1 
ATOM   2710 O OG  . SER   B 1 118 ? -4.92174  -5.99412  -36.12991 1.000 53.41000  ? 332 SER   B OG  1 
ATOM   2711 N N   . THR   B 1 119 ? -4.20202  -8.77518  -34.28729 1.000 40.93000  ? 333 THR   B N   1 
ATOM   2712 C CA  . THR   B 1 119 ? -4.20311  -10.12815 -34.82536 1.000 41.03000  ? 333 THR   B CA  1 
ATOM   2713 C C   . THR   B 1 119 ? -5.51932  -10.33019 -35.55998 1.000 46.43000  ? 333 THR   B C   1 
ATOM   2714 O O   . THR   B 1 119 ? -6.59815  -10.15028 -34.98064 1.000 51.38000  ? 333 THR   B O   1 
ATOM   2715 C CB  . THR   B 1 119 ? -4.04171  -11.16721 -33.71247 1.000 46.53000  ? 333 THR   B CB  1 
ATOM   2716 O OG1 . THR   B 1 119 ? -2.85049  -10.89918 -32.95682 1.000 50.59000  ? 333 THR   B OG1 1 
ATOM   2717 C CG2 . THR   B 1 119 ? -3.97180  -12.58217 -34.28758 1.000 37.36000  ? 333 THR   B CG2 1 
ATOM   2718 N N   . LYS   B 1 120 ? -5.43169  -10.67911 -36.83302 1.000 46.38000  ? 334 LYS   B N   1 
ATOM   2719 C CA  . LYS   B 1 120 ? -6.59694  -10.81613 -37.69768 1.000 44.56000  ? 334 LYS   B CA  1 
ATOM   2720 C C   . LYS   B 1 120 ? -6.66100  -12.25710 -38.18174 1.000 45.53000  ? 334 LYS   B C   1 
ATOM   2721 O O   . LYS   B 1 120 ? -5.85023  -12.66701 -39.02101 1.000 46.30000  ? 334 LYS   B O   1 
ATOM   2722 C CB  . LYS   B 1 120 ? -6.51435  -9.84305  -38.87065 1.000 46.43000  ? 334 LYS   B CB  1 
ATOM   2723 C CG  . LYS   B 1 120 ? -6.99334  -8.43110  -38.56142 1.000 53.91000  ? 334 LYS   B CG  1 
ATOM   2724 C CD  . LYS   B 1 120 ? -6.97277  -7.52203  -39.80537 1.000 54.52000  ? 334 LYS   B CD  1 
ATOM   2725 C CE  . LYS   B 1 120 ? -7.63077  -6.16408  -39.52609 1.000 51.66000  ? 334 LYS   B CE  1 
ATOM   2726 N NZ  . LYS   B 1 120 ? -7.48117  -5.18901  -40.65308 1.000 57.82000  ? 334 LYS   B NZ  1 
ATOM   2727 N N   . VAL   B 1 121 ? -7.60980  -13.02919 -37.65550 1.000 49.05000  ? 335 VAL   B N   1 
ATOM   2728 C CA  . VAL   B 1 121 ? -7.84787  -14.38117 -38.15750 1.000 48.37000  ? 335 VAL   B CA  1 
ATOM   2729 C C   . VAL   B 1 121 ? -8.66627  -14.28115 -39.43625 1.000 48.82000  ? 335 VAL   B C   1 
ATOM   2730 O O   . VAL   B 1 121 ? -9.76330  -13.71121 -39.43688 1.000 54.97000  ? 335 VAL   B O   1 
ATOM   2731 C CB  . VAL   B 1 121 ? -8.56351  -15.25627 -37.11734 1.000 50.04000  ? 335 VAL   B CB  1 
ATOM   2732 C CG1 . VAL   B 1 121 ? -8.58257  -16.70125 -37.59541 1.000 47.73000  ? 335 VAL   B CG1 1 
ATOM   2733 C CG2 . VAL   B 1 121 ? -7.88810  -15.16431 -35.77354 1.000 49.31000  ? 335 VAL   B CG2 1 
ATOM   2734 N N   . CYS   B 1 122 ? -8.14356  -14.84105 -40.52544 1.000 49.60000  ? 336 CYS   B N   1 
ATOM   2735 C CA  . CYS   B 1 122 ? -8.79096  -14.78502 -41.82724 1.000 51.26000  ? 336 CYS   B CA  1 
ATOM   2736 C C   . CYS   B 1 122 ? -9.09504  -16.17800 -42.35223 1.000 46.67000  ? 336 CYS   B C   1 
ATOM   2737 O O   . CYS   B 1 122 ? -8.32692  -17.11797 -42.14452 1.000 43.76000  ? 336 CYS   B O   1 
ATOM   2738 C CB  . CYS   B 1 122 ? -7.93931  -14.02891 -42.83846 1.000 50.07000  ? 336 CYS   B CB  1 
ATOM   2739 S SG  . CYS   B 1 122 ? -7.23619  -12.52391 -42.13158 1.000 54.13000  ? 336 CYS   B SG  1 
ATOM   2740 N N   . SER   B 1 123 ? -10.23424 -16.29803 -43.02289 1.000 54.21000  ? 337 SER   B N   1 
ATOM   2741 C CA  . SER   B 1 123 ? -10.61638 -17.50901 -43.73284 1.000 52.14000  ? 337 SER   B CA  1 
ATOM   2742 C C   . SER   B 1 123 ? -10.82785 -17.13194 -45.19376 1.000 54.28000  ? 337 SER   B C   1 
ATOM   2743 O O   . SER   B 1 123 ? -11.53000 -16.15596 -45.48749 1.000 57.57000  ? 337 SER   B O   1 
ATOM   2744 C CB  . SER   B 1 123 ? -11.87216 -18.13212 -43.12350 1.000 45.24000  ? 337 SER   B CB  1 
ATOM   2745 O OG  . SER   B 1 123 ? -12.07425 -19.42710 -43.65351 1.000 51.41000  ? 337 SER   B OG  1 
ATOM   2746 N N   . PHE   B 1 124 ? -10.17408 -17.86985 -46.09900 1.000 55.94000  ? 338 PHE   B N   1 
ATOM   2747 C CA  . PHE   B 1 124 ? -10.17154 -17.57477 -47.54098 1.000 53.65000  ? 338 PHE   B CA  1 
ATOM   2748 C C   . PHE   B 1 124 ? -9.84071  -16.11473 -47.82200 1.000 51.73000  ? 338 PHE   B C   1 
ATOM   2749 O O   . PHE   B 1 124 ? -10.30204 -15.52970 -48.79882 1.000 60.82000  ? 338 PHE   B O   1 
ATOM   2750 C CB  . PHE   B 1 124 ? -11.50071 -17.97281 -48.19560 1.000 46.77000  ? 338 PHE   B CB  1 
ATOM   2751 C CG  . PHE   B 1 124 ? -11.70164 -19.45081 -48.24763 1.000 47.60000  ? 338 PHE   B CG  1 
ATOM   2752 C CD1 . PHE   B 1 124 ? -11.20792 -20.19272 -49.30882 1.000 52.72000  ? 338 PHE   B CD1 1 
ATOM   2753 C CD2 . PHE   B 1 124 ? -12.32129 -20.11391 -47.20148 1.000 48.22000  ? 338 PHE   B CD2 1 
ATOM   2754 C CE1 . PHE   B 1 124 ? -11.35885 -21.57173 -49.33285 1.000 54.09000  ? 338 PHE   B CE1 1 
ATOM   2755 C CE2 . PHE   B 1 124 ? -12.48521 -21.48592 -47.22051 1.000 47.30000  ? 338 PHE   B CE2 1 
ATOM   2756 C CZ  . PHE   B 1 124 ? -12.01349 -22.21983 -48.27969 1.000 48.64000  ? 338 PHE   B CZ  1 
ATOM   2757 N N   . GLY   B 1 125 ? -9.01248  -15.52473 -46.96922 1.000 53.09000  ? 339 GLY   B N   1 
ATOM   2758 C CA  . GLY   B 1 125 ? -8.54662  -14.17269 -47.16328 1.000 50.81000  ? 339 GLY   B CA  1 
ATOM   2759 C C   . GLY   B 1 125 ? -9.40849  -13.10378 -46.53696 1.000 55.04000  ? 339 GLY   B C   1 
ATOM   2760 O O   . GLY   B 1 125 ? -9.07360  -11.91875 -46.65199 1.000 61.87000  ? 339 GLY   B O   1 
ATOM   2761 N N   . LYS   B 1 126 ? -10.49527 -13.47288 -45.86965 1.000 51.19000  ? 340 LYS   B N   1 
ATOM   2762 C CA  . LYS   B 1 126 ? -11.41114 -12.51097 -45.27931 1.000 51.45000  ? 340 LYS   B CA  1 
ATOM   2763 C C   . LYS   B 1 126 ? -11.32968 -12.59105 -43.76534 1.000 56.20000  ? 340 LYS   B C   1 
ATOM   2764 O O   . LYS   B 1 126 ? -11.21544 -13.68408 -43.19944 1.000 55.46000  ? 340 LYS   B O   1 
ATOM   2765 C CB  . LYS   B 1 126 ? -12.84628 -12.75502 -45.76789 1.000 60.11000  ? 340 LYS   B CB  1 
ATOM   2766 C CG  . LYS   B 1 126 ? -12.92170 -13.23994 -47.24990 1.000 59.38000  ? 340 LYS   B CG  1 
ATOM   2767 C CD  . LYS   B 1 126 ? -14.30891 -13.08099 -47.90547 1.000 66.29000  ? 340 LYS   B CD  1 
ATOM   2768 C CE  . LYS   B 1 126 ? -15.02191 -14.43101 -48.17333 1.000 72.05000  ? 340 LYS   B CE  1 
ATOM   2769 N NZ  . LYS   B 1 126 ? -16.52400 -14.32908 -48.42886 1.000 66.59000  ? 340 LYS   B NZ  1 
ATOM   2770 N N   . GLN   B 1 127 ? -11.37355 -11.42509 -43.11926 1.000 55.59000  ? 341 GLN   B N   1 
ATOM   2771 C CA  . GLN   B 1 127 ? -11.27311 -11.34417 -41.66329 1.000 50.22000  ? 341 GLN   B CA  1 
ATOM   2772 C C   . GLN   B 1 127 ? -12.52488 -11.91528 -40.99594 1.000 51.73000  ? 341 GLN   B C   1 
ATOM   2773 O O   . GLN   B 1 127 ? -13.63999 -11.46633 -41.26158 1.000 55.23000  ? 341 GLN   B O   1 
ATOM   2774 C CB  . GLN   B 1 127 ? -11.07207 -9.89518  -41.22926 1.000 48.38000  ? 341 GLN   B CB  1 
ATOM   2775 C CG  . GLN   B 1 127 ? -11.50665 -9.62329  -39.80312 1.000 54.00000  ? 341 GLN   B CG  1 
ATOM   2776 C CD  . GLN   B 1 127 ? -11.16959 -8.20830  -39.34514 1.000 60.27000  ? 341 GLN   B CD  1 
ATOM   2777 O OE1 . GLN   B 1 127 ? -10.38483 -7.48921  -39.99433 1.000 57.39000  ? 341 GLN   B OE1 1 
ATOM   2778 N NE2 . GLN   B 1 127 ? -11.77028 -7.79440  -38.22293 1.000 50.26000  ? 341 GLN   B NE2 1 
ATOM   2779 N N   . VAL   B 1 128 ? -12.33755 -12.88732 -40.11605 1.000 50.83000  ? 342 VAL   B N   1 
ATOM   2780 C CA  . VAL   B 1 128 ? -13.43628 -13.41343 -39.32475 1.000 52.41000  ? 342 VAL   B CA  1 
ATOM   2781 C C   . VAL   B 1 128 ? -13.31586 -13.05951 -37.84977 1.000 56.79000  ? 342 VAL   B C   1 
ATOM   2782 O O   . VAL   B 1 128 ? -14.32363 -13.13161 -37.12746 1.000 58.32000  ? 342 VAL   B O   1 
ATOM   2783 C CB  . VAL   B 1 128 ? -13.57025 -14.93843 -39.50180 1.000 52.23000  ? 342 VAL   B CB  1 
ATOM   2784 C CG1 . VAL   B 1 128 ? -13.71767 -15.27235 -40.96377 1.000 52.57000  ? 342 VAL   B CG1 1 
ATOM   2785 C CG2 . VAL   B 1 128 ? -12.35803 -15.63639 -38.92421 1.000 51.05000  ? 342 VAL   B CG2 1 
ATOM   2786 N N   . VAL   B 1 129 ? -12.13173 -12.69147 -37.37210 1.000 54.30000  ? 343 VAL   B N   1 
ATOM   2787 C CA  . VAL   B 1 129 ? -11.95534 -12.24354 -35.99713 1.000 51.87000  ? 343 VAL   B CA  1 
ATOM   2788 C C   . VAL   B 1 129 ? -10.91441 -11.13648 -36.00738 1.000 49.16000  ? 343 VAL   B C   1 
ATOM   2789 O O   . VAL   B 1 129 ? -10.07168 -11.06337 -36.90364 1.000 52.69000  ? 343 VAL   B O   1 
ATOM   2790 C CB  . VAL   B 1 129 ? -11.51099 -13.40056 -35.06133 1.000 54.29000  ? 343 VAL   B CB  1 
ATOM   2791 C CG1 . VAL   B 1 129 ? -11.30358 -12.91664 -33.63337 1.000 49.74000  ? 343 VAL   B CG1 1 
ATOM   2792 C CG2 . VAL   B 1 129 ? -12.48293 -14.57462 -35.10111 1.000 50.82000  ? 343 VAL   B CG2 1 
ATOM   2793 N N   . GLU   B 1 130 ? -10.97015 -10.26654 -35.00632 1.000 46.60000  ? 344 GLU   B N   1 
ATOM   2794 C CA  . GLU   B 1 130 ? -9.83312  -9.40949  -34.71161 1.000 51.74000  ? 344 GLU   B CA  1 
ATOM   2795 C C   . GLU   B 1 130 ? -9.74468  -9.15157  -33.21562 1.000 50.49000  ? 344 GLU   B C   1 
ATOM   2796 O O   . GLU   B 1 130 ? -10.71052 -8.67666  -32.60330 1.000 48.70000  ? 344 GLU   B O   1 
ATOM   2797 C CB  . GLU   B 1 130 ? -9.91142  -8.07845  -35.45351 1.000 53.61000  ? 344 GLU   B CB  1 
ATOM   2798 C CG  . GLU   B 1 130 ? -8.61542  -7.30038  -35.32386 1.000 53.94000  ? 344 GLU   B CG  1 
ATOM   2799 C CD  . GLU   B 1 130 ? -8.71168  -5.90935  -35.91575 1.000 59.21000  ? 344 GLU   B CD  1 
ATOM   2800 O OE1 . GLU   B 1 130 ? -9.82685  -5.54639  -36.38139 1.000 52.97000  ? 344 GLU   B OE1 1 
ATOM   2801 O OE2 . GLU   B 1 130 ? -7.67872  -5.18629  -35.89202 1.000 58.61000  ? 344 GLU   B OE2 1 
ATOM   2802 N N   . LYS   B 1 131 ? -8.58348  -9.46253  -32.63200 1.000 55.10000  ? 345 LYS   B N   1 
ATOM   2803 C CA  . LYS   B 1 131 ? -8.25209  -9.08559  -31.26107 1.000 45.56000  ? 345 LYS   B CA  1 
ATOM   2804 C C   . LYS   B 1 131 ? -7.23317  -7.96053  -31.30832 1.000 47.12000  ? 345 LYS   B C   1 
ATOM   2805 O O   . LYS   B 1 131 ? -6.34042  -7.97443  -32.15759 1.000 50.87000  ? 345 LYS   B O   1 
ATOM   2806 C CB  . LYS   B 1 131 ? -7.67278  -10.25861 -30.48232 1.000 45.64000  ? 345 LYS   B CB  1 
ATOM   2807 C CG  . LYS   B 1 131 ? -7.88033  -10.12771 -28.97825 1.000 54.54000  ? 345 LYS   B CG  1 
ATOM   2808 C CD  . LYS   B 1 131 ? -7.07103  -11.14870 -28.19155 1.000 57.32000  ? 345 LYS   B CD  1 
ATOM   2809 C CE  . LYS   B 1 131 ? -7.77462  -11.51182 -26.90136 1.000 64.19000  ? 345 LYS   B CE  1 
ATOM   2810 N NZ  . LYS   B 1 131 ? -8.96366  -12.36887 -27.21005 1.000 69.92000  ? 345 LYS   B NZ  1 
ATOM   2811 N N   . VAL   B 1 132 ? -7.37096  -6.97159  -30.43122 1.000 48.26000  ? 346 VAL   B N   1 
ATOM   2812 C CA  . VAL   B 1 132 ? -6.38299  -5.89754  -30.32946 1.000 46.50000  ? 346 VAL   B CA  1 
ATOM   2813 C C   . VAL   B 1 132 ? -5.89856  -5.81959  -28.89460 1.000 45.55000  ? 346 VAL   B C   1 
ATOM   2814 O O   . VAL   B 1 132 ? -6.70928  -5.73770  -27.96635 1.000 51.38000  ? 346 VAL   B O   1 
ATOM   2815 C CB  . VAL   B 1 132 ? -6.93820  -4.53455  -30.77121 1.000 45.88000  ? 346 VAL   B CB  1 
ATOM   2816 C CG1 . VAL   B 1 132 ? -5.93816  -3.44651  -30.41545 1.000 41.29000  ? 346 VAL   B CG1 1 
ATOM   2817 C CG2 . VAL   B 1 132 ? -7.20165  -4.53748  -32.24713 1.000 39.26000  ? 346 VAL   B CG2 1 
ATOM   2818 N N   . GLU   B 1 133 ? -4.58250  -5.80353  -28.72000 1.000 53.42000  ? 347 GLU   B N   1 
ATOM   2819 C CA  . GLU   B 1 133 ? -3.95910  -5.85957  -27.40219 1.000 47.53000  ? 347 GLU   B CA  1 
ATOM   2820 C C   . GLU   B 1 133 ? -2.99312  -4.69252  -27.23442 1.000 43.14000  ? 347 GLU   B C   1 
ATOM   2821 O O   . GLU   B 1 133 ? -2.33443  -4.27243  -28.18159 1.000 45.63000  ? 347 GLU   B O   1 
ATOM   2822 C CB  . GLU   B 1 133 ? -3.25596  -7.22454  -27.20748 1.000 40.94000  ? 347 GLU   B CB  1 
ATOM   2823 C CG  . GLU   B 1 133 ? -4.28290  -8.35760  -27.23224 1.000 42.67000  ? 347 GLU   B CG  1 
ATOM   2824 C CD  . GLU   B 1 133 ? -3.70582  -9.76156  -27.22149 1.000 48.10000  ? 347 GLU   B CD  1 
ATOM   2825 O OE1 . GLU   B 1 133 ? -2.74103  -10.04046 -27.96580 1.000 55.31000  ? 347 GLU   B OE1 1 
ATOM   2826 O OE2 . GLU   B 1 133 ? -4.24454  -10.60864 -26.47638 1.000 57.08000  ? 347 GLU   B OE2 1 
ATOM   2827 N N   . THR   B 1 134 ? -2.94278  -4.14359  -26.03240 1.000 46.41000  ? 348 THR   B N   1 
ATOM   2828 C CA  . THR   B 1 134 ? -2.01475  -3.06955  -25.71262 1.000 52.15000  ? 348 THR   B CA  1 
ATOM   2829 C C   . THR   B 1 134 ? -0.94244  -3.62254  -24.78898 1.000 55.19000  ? 348 THR   B C   1 
ATOM   2830 O O   . THR   B 1 134 ? -1.25510  -4.30362  -23.80892 1.000 59.71000  ? 348 THR   B O   1 
ATOM   2831 C CB  . THR   B 1 134 ? -2.72462  -1.88563  -25.04434 1.000 48.87000  ? 348 THR   B CB  1 
ATOM   2832 O OG1 . THR   B 1 134 ? -3.74891  -1.40064  -25.91500 1.000 50.57000  ? 348 THR   B OG1 1 
ATOM   2833 C CG2 . THR   B 1 134 ? -1.73759  -0.74259  -24.75257 1.000 47.21000  ? 348 THR   B CG2 1 
ATOM   2834 N N   . GLU   B 1 135 ? 0.31445   -3.34345  -25.09434 1.000 56.37000  ? 349 GLU   B N   1 
ATOM   2835 C CA  . GLU   B 1 135 ? 1.38374   -3.82144  -24.24170 1.000 53.86000  ? 349 GLU   B CA  1 
ATOM   2836 C C   . GLU   B 1 135 ? 2.39974   -2.71339  -24.01594 1.000 58.29000  ? 349 GLU   B C   1 
ATOM   2837 O O   . GLU   B 1 135 ? 2.64143   -1.87733  -24.89897 1.000 55.73000  ? 349 GLU   B O   1 
ATOM   2838 C CB  . GLU   B 1 135 ? 2.05364   -5.05837  -24.82497 1.000 52.54000  ? 349 GLU   B CB  1 
ATOM   2839 C CG  . GLU   B 1 135 ? 2.75001   -5.87639  -23.76323 1.000 54.89000  ? 349 GLU   B CG  1 
ATOM   2840 C CD  . GLU   B 1 135 ? 1.91140   -5.98151  -22.49498 1.000 60.63000  ? 349 GLU   B CD  1 
ATOM   2841 O OE1 . GLU   B 1 135 ? 0.75039   -6.47057  -22.60266 1.000 54.55000  ? 349 GLU   B OE1 1 
ATOM   2842 O OE2 . GLU   B 1 135 ? 2.41070   -5.56254  -21.41011 1.000 57.45000  ? 349 GLU   B OE2 1 
ATOM   2843 N N   . TYR   B 1 136 ? 2.98011   -2.72643  -22.80812 1.000 54.40000  ? 350 TYR   B N   1 
ATOM   2844 C CA  . TYR   B 1 136 ? 3.83421   -1.66641  -22.29632 1.000 52.50000  ? 350 TYR   B CA  1 
ATOM   2845 C C   . TYR   B 1 136 ? 5.27827   -2.12833  -22.16378 1.000 46.67000  ? 350 TYR   B C   1 
ATOM   2846 O O   . TYR   B 1 136 ? 5.56041   -3.30633  -21.92794 1.000 44.96000  ? 350 TYR   B O   1 
ATOM   2847 C CB  . TYR   B 1 136 ? 3.34459   -1.17752  -20.93614 1.000 56.72000  ? 350 TYR   B CB  1 
ATOM   2848 C CG  . TYR   B 1 136 ? 2.00153   -0.53159  -21.01569 1.000 59.90000  ? 350 TYR   B CG  1 
ATOM   2849 C CD1 . TYR   B 1 136 ? 1.89138   0.83542   -21.23258 1.000 66.69000  ? 350 TYR   B CD1 1 
ATOM   2850 C CD2 . TYR   B 1 136 ? 0.83462   -1.27067  -20.84338 1.000 62.86000  ? 350 TYR   B CD2 1 
ATOM   2851 C CE1 . TYR   B 1 136 ? 0.66332   1.44735   -21.32317 1.000 68.22000  ? 350 TYR   B CE1 1 
ATOM   2852 C CE2 . TYR   B 1 136 ? -0.40744  -0.66074  -20.92397 1.000 60.17000  ? 350 TYR   B CE2 1 
ATOM   2853 C CZ  . TYR   B 1 136 ? -0.48059  0.69927   -21.15887 1.000 69.96000  ? 350 TYR   B CZ  1 
ATOM   2854 O OH  . TYR   B 1 136 ? -1.70265  1.32821   -21.23546 1.000 82.40000  ? 350 TYR   B OH  1 
ATOM   2855 N N   . ALA   B 1 137 ? 6.18418   -1.16627  -22.28900 1.000 50.79000  ? 351 ALA   B N   1 
ATOM   2856 C CA  . ALA   B 1 137 ? 7.61618   -1.43719  -22.33545 1.000 50.58000  ? 351 ALA   B CA  1 
ATOM   2857 C C   . ALA   B 1 137 ? 8.20261   -1.59423  -20.94164 1.000 50.41000  ? 351 ALA   B C   1 
ATOM   2858 O O   . ALA   B 1 137 ? 8.00483   -0.73729  -20.07953 1.000 57.67000  ? 351 ALA   B O   1 
ATOM   2859 C CB  . ALA   B 1 137 ? 8.33690   -0.30010  -23.04361 1.000 51.19000  ? 351 ALA   B CB  1 
ATOM   2860 N N   . ARG   B 1 138 ? 8.93574   -2.67920  -20.72492 1.000 50.56000  ? 352 ARG   B N   1 
ATOM   2861 C CA  . ARG   B 1 138 ? 9.65114   -2.92823  -19.47616 1.000 56.88000  ? 352 ARG   B CA  1 
ATOM   2862 C C   . ARG   B 1 138 ? 11.14905  -2.93913  -19.76461 1.000 53.54000  ? 352 ARG   B C   1 
ATOM   2863 O O   . ARG   B 1 138 ? 11.59581  -3.63205  -20.68279 1.000 56.85000  ? 352 ARG   B O   1 
ATOM   2864 C CB  . ARG   B 1 138 ? 9.22140   -4.26629  -18.86610 1.000 57.28000  ? 352 ARG   B CB  1 
ATOM   2865 C CG  . ARG   B 1 138 ? 7.73439   -4.56137  -18.96967 1.000 54.03000  ? 352 ARG   B CG  1 
ATOM   2866 C CD  . ARG   B 1 138 ? 7.39162   -5.96242  -18.45465 1.000 58.22000  ? 352 ARG   B CD  1 
ATOM   2867 N NE  . ARG   B 1 138 ? 5.95762   -6.23050  -18.52123 1.000 59.44000  ? 352 ARG   B NE  1 
ATOM   2868 C CZ  . ARG   B 1 138 ? 5.08488   -5.86461  -17.58894 1.000 58.02000  ? 352 ARG   B CZ  1 
ATOM   2869 N NH1 . ARG   B 1 138 ? 5.45616   -5.15565  -16.53101 1.000 56.51000  ? 352 ARG   B NH1 1 
ATOM   2870 N NH2 . ARG   B 1 138 ? 3.80586   -6.20968  -17.72357 1.000 57.34000  ? 352 ARG   B NH2 1 
ATOM   2871 N N   . LEU   B 1 139 ? 11.93623  -2.17913  -19.00981 1.000 52.05000  ? 353 LEU   B N   1 
ATOM   2872 C CA  . LEU   B 1 139 ? 13.37315  -2.14303  -19.27824 1.000 55.78000  ? 353 LEU   B CA  1 
ATOM   2873 C C   . LEU   B 1 139 ? 14.07743  -3.30403  -18.58052 1.000 52.93000  ? 353 LEU   B C   1 
ATOM   2874 O O   . LEU   B 1 139 ? 14.03581  -3.40410  -17.35452 1.000 59.41000  ? 353 LEU   B O   1 
ATOM   2875 C CB  . LEU   B 1 139 ? 13.99120  -0.81302  -18.85435 1.000 54.73000  ? 353 LEU   B CB  1 
ATOM   2876 C CG  . LEU   B 1 139 ? 15.51824  -0.85793  -18.73782 1.000 59.12000  ? 353 LEU   B CG  1 
ATOM   2877 C CD1 . LEU   B 1 139 ? 16.20281  -0.79381  -20.13902 1.000 48.05000  ? 353 LEU   B CD1 1 
ATOM   2878 C CD2 . LEU   B 1 139 ? 15.97844  0.30004   -17.85489 1.000 48.42000  ? 353 LEU   B CD2 1 
ATOM   2879 N N   . GLU   B 1 140 ? 14.71624  -4.18094  -19.36277 1.000 51.90000  ? 354 GLU   B N   1 
ATOM   2880 C CA  . GLU   B 1 140 ? 15.47647  -5.31493  -18.83406 1.000 57.97000  ? 354 GLU   B CA  1 
ATOM   2881 C C   . GLU   B 1 140 ? 16.78525  -5.45881  -19.59147 1.000 58.48000  ? 354 GLU   B C   1 
ATOM   2882 O O   . GLU   B 1 140 ? 16.78389  -5.64874  -20.81048 1.000 63.96000  ? 354 GLU   B O   1 
ATOM   2883 C CB  . GLU   B 1 140 ? 14.69552  -6.63397  -18.91890 1.000 61.55000  ? 354 GLU   B CB  1 
ATOM   2884 C CG  . GLU   B 1 140 ? 13.27168  -6.59608  -18.39747 1.000 60.88000  ? 354 GLU   B CG  1 
ATOM   2885 C CD  . GLU   B 1 140 ? 12.45662  -7.82311  -18.81729 1.000 62.01000  ? 354 GLU   B CD  1 
ATOM   2886 O OE1 . GLU   B 1 140 ? 13.01449  -8.75904  -19.44452 1.000 58.69000  ? 354 GLU   B OE1 1 
ATOM   2887 O OE2 . GLU   B 1 140 ? 11.24972  -7.86320  -18.48893 1.000 60.20000  ? 354 GLU   B OE2 1 
ATOM   2888 N N   . ASN   B 1 141 ? 17.89547  -5.39179  -18.86680 1.000 58.97000  ? 355 ASN   B N   1 
ATOM   2889 C CA  . ASN   B 1 141 ? 19.22130  -5.55168  -19.45622 1.000 64.73000  ? 355 ASN   B CA  1 
ATOM   2890 C C   . ASN   B 1 141 ? 19.47790  -4.52460  -20.55223 1.000 62.89000  ? 355 ASN   B C   1 
ATOM   2891 O O   . ASN   B 1 141 ? 20.12762  -4.81550  -21.55445 1.000 72.90000  ? 355 ASN   B O   1 
ATOM   2892 C CB  . ASN   B 1 141 ? 19.42221  -6.96463  -19.99436 1.000 68.49000  ? 355 ASN   B CB  1 
ATOM   2893 C CG  . ASN   B 1 141 ? 19.72160  -7.95968  -18.90551 1.000 75.42000  ? 355 ASN   B CG  1 
ATOM   2894 O OD1 . ASN   B 1 141 ? 19.20194  -7.85377  -17.79234 1.000 78.52000  ? 355 ASN   B OD1 1 
ATOM   2895 N ND2 . ASN   B 1 141 ? 20.58257  -8.92461  -19.20782 1.000 79.36000  ? 355 ASN   B ND2 1 
ATOM   2896 N N   . GLY   B 1 142 ? 18.97689  -3.30964  -20.36201 1.000 57.91000  ? 356 GLY   B N   1 
ATOM   2897 C CA  . GLY   B 1 142 ? 19.26455  -2.23757  -21.29104 1.000 61.42000  ? 356 GLY   B CA  1 
ATOM   2898 C C   . GLY   B 1 142 ? 18.44916  -2.25754  -22.56379 1.000 64.93000  ? 356 GLY   B C   1 
ATOM   2899 O O   . GLY   B 1 142 ? 18.67285  -1.40848  -23.43681 1.000 64.30000  ? 356 GLY   B O   1 
ATOM   2900 N N   . ARG   B 1 143 ? 17.49319  -3.15859  -22.65255 1.000 64.07000  ? 357 ARG   B N   1 
ATOM   2901 C CA  . ARG   B 1 143 ? 16.60184  -3.18958  -23.79128 1.000 60.90000  ? 357 ARG   B CA  1 
ATOM   2902 C C   . ARG   B 1 143 ? 15.19300  -3.09669  -23.24985 1.000 59.38000  ? 357 ARG   B C   1 
ATOM   2903 O O   . ARG   B 1 143 ? 14.94137  -3.39877  -22.09379 1.000 58.47000  ? 357 ARG   B O   1 
ATOM   2904 C CB  . ARG   B 1 143 ? 16.78667  -4.47052  -24.58841 1.000 57.75000  ? 357 ARG   B CB  1 
ATOM   2905 C CG  . ARG   B 1 143 ? 18.07444  -4.53840  -25.37881 1.000 70.33000  ? 357 ARG   B CG  1 
ATOM   2906 C CD  . ARG   B 1 143 ? 17.88698  -3.95033  -26.76572 1.000 78.11000  ? 357 ARG   B CD  1 
ATOM   2907 N NE  . ARG   B 1 143 ? 16.88879  -4.68335  -27.53946 1.000 77.72000  ? 357 ARG   B NE  1 
ATOM   2908 C CZ  . ARG   B 1 143 ? 16.56539  -4.39829  -28.79434 1.000 67.53000  ? 357 ARG   B CZ  1 
ATOM   2909 N NH1 . ARG   B 1 143 ? 17.16614  -3.39922  -29.42147 1.000 61.48000  ? 357 ARG   B NH1 1 
ATOM   2910 N NH2 . ARG   B 1 143 ? 15.64824  -5.11231  -29.42410 1.000 67.40000  ? 357 ARG   B NH2 1 
ATOM   2911 N N   . PHE   B 1 144 ? 14.26872  -2.66970  -24.08454 1.000 56.86000  ? 358 PHE   B N   1 
ATOM   2912 C CA  . PHE   B 1 144 ? 12.88385  -2.59680  -23.65412 1.000 55.25000  ? 358 PHE   B CA  1 
ATOM   2913 C C   . PHE   B 1 144 ? 12.14278  -3.83482  -24.12997 1.000 51.47000  ? 358 PHE   B C   1 
ATOM   2914 O O   . PHE   B 1 144 ? 12.19044  -4.17075  -25.31300 1.000 49.12000  ? 358 PHE   B O   1 
ATOM   2915 C CB  . PHE   B 1 144 ? 12.23661  -1.32581  -24.17885 1.000 53.57000  ? 358 PHE   B CB  1 
ATOM   2916 C CG  . PHE   B 1 144 ? 12.72875  -0.08382  -23.48793 1.000 56.43000  ? 358 PHE   B CG  1 
ATOM   2917 C CD1 . PHE   B 1 144 ? 12.09407  0.38907   -22.33571 1.000 50.47000  ? 358 PHE   B CD1 1 
ATOM   2918 C CD2 . PHE   B 1 144 ? 13.85757  0.58227   -23.96023 1.000 48.13000  ? 358 PHE   B CD2 1 
ATOM   2919 C CE1 . PHE   B 1 144 ? 12.54520  1.53006   -21.69478 1.000 48.20000  ? 358 PHE   B CE1 1 
ATOM   2920 C CE2 . PHE   B 1 144 ? 14.31569  1.72426   -23.33030 1.000 48.50000  ? 358 PHE   B CE2 1 
ATOM   2921 C CZ  . PHE   B 1 144 ? 13.65501  2.20516   -22.19008 1.000 53.83000  ? 358 PHE   B CZ  1 
ATOM   2922 N N   . VAL   B 1 145 ? 11.49110  -4.52191  -23.19581 1.000 48.52000  ? 359 VAL   B N   1 
ATOM   2923 C CA  . VAL   B 1 145 ? 10.85410  -5.80993  -23.42869 1.000 47.53000  ? 359 VAL   B CA  1 
ATOM   2924 C C   . VAL   B 1 145 ? 9.35213   -5.62703  -23.30822 1.000 52.23000  ? 359 VAL   B C   1 
ATOM   2925 O O   . VAL   B 1 145 ? 8.86534   -4.87111  -22.46003 1.000 56.70000  ? 359 VAL   B O   1 
ATOM   2926 C CB  . VAL   B 1 145 ? 11.35747  -6.87496  -22.43190 1.000 53.60000  ? 359 VAL   B CB  1 
ATOM   2927 C CG1 . VAL   B 1 145 ? 10.83644  -8.27197  -22.79583 1.000 51.85000  ? 359 VAL   B CG1 1 
ATOM   2928 C CG2 . VAL   B 1 145 ? 12.86948  -6.85988  -22.37936 1.000 53.33000  ? 359 VAL   B CG2 1 
ATOM   2929 N N   . TYR   B 1 146 ? 8.61791   -6.30502  -24.16804 1.000 48.16000  ? 360 TYR   B N   1 
ATOM   2930 C CA  . TYR   B 1 146 ? 7.17093   -6.30811  -24.10460 1.000 44.30000  ? 360 TYR   B CA  1 
ATOM   2931 C C   . TYR   B 1 146 ? 6.74605   -7.76114  -23.98255 1.000 47.47000  ? 360 TYR   B C   1 
ATOM   2932 O O   . TYR   B 1 146 ? 7.17886   -8.60007  -24.77573 1.000 47.58000  ? 360 TYR   B O   1 
ATOM   2933 C CB  . TYR   B 1 146 ? 6.57051   -5.63407  -25.34038 1.000 53.33000  ? 360 TYR   B CB  1 
ATOM   2934 C CG  . TYR   B 1 146 ? 7.15633   -4.26002  -25.69048 1.000 54.67000  ? 360 TYR   B CG  1 
ATOM   2935 C CD1 . TYR   B 1 146 ? 8.45317   -4.13292  -26.17886 1.000 51.46000  ? 360 TYR   B CD1 1 
ATOM   2936 C CD2 . TYR   B 1 146 ? 6.38129   -3.10407  -25.59217 1.000 53.24000  ? 360 TYR   B CD2 1 
ATOM   2937 C CE1 . TYR   B 1 146 ? 8.97700   -2.89787  -26.51195 1.000 51.93000  ? 360 TYR   B CE1 1 
ATOM   2938 C CE2 . TYR   B 1 146 ? 6.90211   -1.86502  -25.92826 1.000 52.10000  ? 360 TYR   B CE2 1 
ATOM   2939 C CZ  . TYR   B 1 146 ? 8.19797   -1.77192  -26.39365 1.000 51.49000  ? 360 TYR   B CZ  1 
ATOM   2940 O OH  . TYR   B 1 146 ? 8.73479   -0.55287  -26.72874 1.000 49.01000  ? 360 TYR   B OH  1 
ATOM   2941 N N   . ARG   B 1 147 ? 5.88235   -8.03925  -23.02931 1.000 52.29000  ? 361 ARG   B N   1 
ATOM   2942 C CA  . ARG   B 1 147 ? 5.44849   -9.39228  -22.82725 1.000 51.39000  ? 361 ARG   B CA  1 
ATOM   2943 C C   . ARG   B 1 147 ? 3.96253   -9.57837  -22.75881 1.000 47.25000  ? 361 ARG   B C   1 
ATOM   2944 O O   . ARG   B 1 147 ? 3.31876   -9.02846  -21.88759 1.000 58.45000  ? 361 ARG   B O   1 
ATOM   2945 C CB  . ARG   B 1 147 ? 6.02792   -9.93133  -21.52846 1.000 53.23000  ? 361 ARG   B CB  1 
ATOM   2946 C CG  . ARG   B 1 147 ? 7.52094   -10.17024 -21.51293 1.000 55.69000  ? 361 ARG   B CG  1 
ATOM   2947 C CD  . ARG   B 1 147 ? 7.91438   -10.81829 -20.19708 1.000 56.12000  ? 361 ARG   B CD  1 
ATOM   2948 N NE  . ARG   B 1 147 ? 9.08238   -11.67122 -20.33649 1.000 51.41000  ? 361 ARG   B NE  1 
ATOM   2949 C CZ  . ARG   B 1 147 ? 10.32542  -11.26716 -20.13284 1.000 60.05000  ? 361 ARG   B CZ  1 
ATOM   2950 N NH1 . ARG   B 1 147 ? 10.55846  -10.02016 -19.77184 1.000 63.08000  ? 361 ARG   B NH1 1 
ATOM   2951 N NH2 . ARG   B 1 147 ? 11.33342  -12.10809 -20.28920 1.000 57.68000  ? 361 ARG   B NH2 1 
ATOM   2952 N N   . ILE   B 1 148 ? 3.40729   -10.32435 -23.68969 1.000 50.05000  ? 362 ILE   B N   1 
ATOM   2953 C CA  . ILE   B 1 148 ? 2.00033   -10.70544 -23.62928 1.000 43.79000  ? 362 ILE   B CA  1 
ATOM   2954 C C   . ILE   B 1 148 ? 1.98055   -12.15647 -23.18336 1.000 48.98000  ? 362 ILE   B C   1 
ATOM   2955 O O   . ILE   B 1 148 ? 2.33737   -13.06240 -23.95152 1.000 42.06000  ? 362 ILE   B O   1 
ATOM   2956 C CB  . ILE   B 1 148 ? 1.26791   -10.51740 -24.96005 1.000 46.52000  ? 362 ILE   B CB  1 
ATOM   2957 C CG1 . ILE   B 1 148 ? 0.77979   -9.07343  -25.08982 1.000 52.93000  ? 362 ILE   B CG1 1 
ATOM   2958 C CG2 . ILE   B 1 148 ? 0.04994   -11.42647 -25.03473 1.000 42.37000  ? 362 ILE   B CG2 1 
ATOM   2959 C CD1 . ILE   B 1 148 ? 0.63332   -8.58535  -26.54274 1.000 50.52000  ? 362 ILE   B CD1 1 
ATOM   2960 N N   . HIS   B 1 149 ? 1.58894   -12.35356 -21.92225 1.000 53.31000  ? 363 HIS   B N   1 
ATOM   2961 C CA  . HIS   B 1 149 ? 1.66423   -13.62260 -21.21635 1.000 46.63000  ? 363 HIS   B CA  1 
ATOM   2962 C C   . HIS   B 1 149 ? 0.28127   -14.25768 -21.19296 1.000 51.69000  ? 363 HIS   B C   1 
ATOM   2963 O O   . HIS   B 1 149 ? -0.70266  -13.58776 -20.85863 1.000 54.39000  ? 363 HIS   B O   1 
ATOM   2964 C CB  . HIS   B 1 149 ? 2.17365   -13.37265 -19.79449 1.000 54.48000  ? 363 HIS   B CB  1 
ATOM   2965 C CG  . HIS   B 1 149 ? 2.34697   -14.61169 -18.96461 1.000 66.23000  ? 363 HIS   B CG  1 
ATOM   2966 N ND1 . HIS   B 1 149 ? 3.46700   -15.41762 -19.04300 1.000 68.73000  ? 363 HIS   B ND1 1 
ATOM   2967 C CD2 . HIS   B 1 149 ? 1.55229   -15.16579 -18.01740 1.000 63.04000  ? 363 HIS   B CD2 1 
ATOM   2968 C CE1 . HIS   B 1 149 ? 3.34931   -16.41967 -18.18702 1.000 66.01000  ? 363 HIS   B CE1 1 
ATOM   2969 N NE2 . HIS   B 1 149 ? 2.19550   -16.29278 -17.55366 1.000 66.61000  ? 363 HIS   B NE2 1 
ATOM   2970 N N   . ARG   B 1 150 ? 0.20524   -15.53466 -21.55402 1.000 49.35000  ? 364 ARG   B N   1 
ATOM   2971 C CA  . ARG   B 1 150 ? -1.02368  -16.33874 -21.45869 1.000 54.44000  ? 364 ARG   B CA  1 
ATOM   2972 C C   . ARG   B 1 150 ? -2.27588  -15.57579 -21.93926 1.000 53.15000  ? 364 ARG   B C   1 
ATOM   2973 O O   . ARG   B 1 150 ? -3.24266  -15.39088 -21.20096 1.000 56.10000  ? 364 ARG   B O   1 
ATOM   2974 C CB  . ARG   B 1 150 ? -1.22322  -16.84584 -20.02066 1.000 52.54000  ? 364 ARG   B CB  1 
ATOM   2975 C CG  . ARG   B 1 150 ? -0.54203  -18.19282 -19.67394 1.000 57.00000  ? 364 ARG   B CG  1 
ATOM   2976 C CD  . ARG   B 1 150 ? -0.95858  -18.66392 -18.27984 1.000 50.36000  ? 364 ARG   B CD  1 
ATOM   2977 N NE  . ARG   B 1 150 ? -1.83353  -19.82797 -18.31464 1.000 47.07000  ? 364 ARG   B NE  1 
ATOM   2978 C CZ  . ARG   B 1 150 ? -3.14847  -19.75606 -18.11724 1.000 62.94000  ? 364 ARG   B CZ  1 
ATOM   2979 N NH1 . ARG   B 1 150 ? -3.77050  -18.58810 -18.00198 1.000 61.23000  ? 364 ARG   B NH1 1 
ATOM   2980 N NH2 . ARG   B 1 150 ? -3.86639  -20.87910 -18.06209 1.000 57.84000  ? 364 ARG   B NH2 1 
ATOM   2981 N N   . SER   B 1 151 ? -2.25729  -15.13271 -23.20324 1.000 55.77000  ? 365 SER   B N   1 
ATOM   2982 C CA  . SER   B 1 151 ? -3.44049  -14.46075 -23.76385 1.000 52.18000  ? 365 SER   B CA  1 
ATOM   2983 C C   . SER   B 1 151 ? -4.49455  -15.49279 -24.14759 1.000 53.18000  ? 365 SER   B C   1 
ATOM   2984 O O   . SER   B 1 151 ? -4.17370  -16.47273 -24.83074 1.000 50.19000  ? 365 SER   B O   1 
ATOM   2985 C CB  . SER   B 1 151 ? -3.07492  -13.61966 -24.98791 1.000 51.11000  ? 365 SER   B CB  1 
ATOM   2986 O OG  . SER   B 1 151 ? -4.21512  -12.98269 -25.53553 1.000 50.93000  ? 365 SER   B OG  1 
ATOM   2987 N N   . PRO   B 1 152 ? -5.75044  -15.29888 -23.75619 1.000 52.02000  ? 366 PRO   B N   1 
ATOM   2988 C CA  . PRO   B 1 152 ? -6.73544  -16.36393 -23.93395 1.000 52.55000  ? 366 PRO   B CA  1 
ATOM   2989 C C   . PRO   B 1 152 ? -7.21087  -16.40687 -25.37081 1.000 50.72000  ? 366 PRO   B C   1 
ATOM   2990 O O   . PRO   B 1 152 ? -7.49812  -15.37686 -25.98667 1.000 53.52000  ? 366 PRO   B O   1 
ATOM   2991 C CB  . PRO   B 1 152 ? -7.85817  -15.95305 -22.98959 1.000 55.89000  ? 366 PRO   B CB  1 
ATOM   2992 C CG  . PRO   B 1 152 ? -7.80028  -14.46504 -23.05052 1.000 62.59000  ? 366 PRO   B CG  1 
ATOM   2993 C CD  . PRO   B 1 152 ? -6.34532  -14.11695 -23.11594 1.000 55.12000  ? 366 PRO   B CD  1 
ATOM   2994 N N   . MET   B 1 153 ? -7.28496  -17.61185 -25.90586 1.000 46.77000  ? 367 MET   B N   1 
ATOM   2995 C CA  . MET   B 1 153 ? -7.72437  -17.75979 -27.27874 1.000 52.90000  ? 367 MET   B CA  1 
ATOM   2996 C C   . MET   B 1 153 ? -9.20243  -17.42587 -27.40227 1.000 55.73000  ? 367 MET   B C   1 
ATOM   2997 O O   . MET   B 1 153 ? -10.01315 -17.82897 -26.56604 1.000 57.69000  ? 367 MET   B O   1 
ATOM   2998 C CB  . MET   B 1 153 ? -7.47843  -19.18175 -27.75889 1.000 54.35000  ? 367 MET   B CB  1 
ATOM   2999 C CG  . MET   B 1 153 ? -6.14662  -19.36764 -28.41931 1.000 46.61000  ? 367 MET   B CG  1 
ATOM   3000 S SD  . MET   B 1 153 ? -6.04977  -20.98659 -29.20343 1.000 56.42000  ? 367 MET   B SD  1 
ATOM   3001 C CE  . MET   B 1 153 ? -4.28873  -21.30249 -29.13298 1.000 49.29000  ? 367 MET   B CE  1 
ATOM   3002 N N   . CYS   B 1 154 ? -9.55079  -16.69083 -28.45812 1.000 57.39000  ? 368 CYS   B N   1 
ATOM   3003 C CA  . CYS   B 1 154 ? -10.95389 -16.40890 -28.73268 1.000 60.68000  ? 368 CYS   B CA  1 
ATOM   3004 C C   . CYS   B 1 154 ? -11.68493 -17.69492 -29.11053 1.000 57.55000  ? 368 CYS   B C   1 
ATOM   3005 O O   . CYS   B 1 154 ? -11.07499 -18.69086 -29.50877 1.000 56.83000  ? 368 CYS   B O   1 
ATOM   3006 C CB  . CYS   B 1 154 ? -11.09629 -15.38084 -29.84857 1.000 60.60000  ? 368 CYS   B CB  1 
ATOM   3007 S SG  . CYS   B 1 154 ? -10.22173 -15.84370 -31.36987 1.000 52.17000  ? 368 CYS   B SG  1 
ATOM   3008 N N   . GLU   B 1 155 ? -13.01689 -17.66500 -28.97012 1.000 63.80000  ? 369 GLU   B N   1 
ATOM   3009 C CA  . GLU   B 1 155 ? -13.80987 -18.88504 -29.12895 1.000 61.63000  ? 369 GLU   B CA  1 
ATOM   3010 C C   . GLU   B 1 155 ? -13.66226 -19.44995 -30.52603 1.000 57.34000  ? 369 GLU   B C   1 
ATOM   3011 O O   . GLU   B 1 155 ? -13.58024 -20.67494 -30.70712 1.000 54.24000  ? 369 GLU   B O   1 
ATOM   3012 C CB  . GLU   B 1 155 ? -15.28079 -18.61414 -28.82549 1.000 67.20000  ? 369 GLU   B CB  1 
ATOM   3013 C CG  . GLU   B 1 155 ? -15.97551 -19.75523 -28.10834 1.000 79.40000  ? 369 GLU   B CG  1 
ATOM   3014 C CD  . GLU   B 1 155 ? -17.44061 -19.87929 -28.48491 1.000 89.08000  ? 369 GLU   B CD  1 
ATOM   3015 O OE1 . GLU   B 1 155 ? -18.01782 -18.87330 -28.95567 1.000 91.03000  ? 369 GLU   B OE1 1 
ATOM   3016 O OE2 . GLU   B 1 155 ? -18.01449 -20.97334 -28.29079 1.000 95.08000  ? 369 GLU   B OE2 1 
ATOM   3017 N N   . TYR   B 1 156 ? -13.60961 -18.55889 -31.52099 1.000 58.95000  ? 370 TYR   B N   1 
ATOM   3018 C CA  . TYR   B 1 156 ? -13.44801 -18.95780 -32.91307 1.000 49.33000  ? 370 TYR   B CA  1 
ATOM   3019 C C   . TYR   B 1 156 ? -12.28901 -19.92772 -33.08647 1.000 51.53000  ? 370 TYR   B C   1 
ATOM   3020 O O   . TYR   B 1 156 ? -12.43513 -20.99070 -33.70549 1.000 52.59000  ? 370 TYR   B O   1 
ATOM   3021 C CB  . TYR   B 1 156 ? -13.23235 -17.72374 -33.77306 1.000 46.79000  ? 370 TYR   B CB  1 
ATOM   3022 C CG  . TYR   B 1 156 ? -13.16776 -18.07965 -35.22110 1.000 54.34000  ? 370 TYR   B CG  1 
ATOM   3023 C CD1 . TYR   B 1 156 ? -14.33097 -18.27868 -35.94476 1.000 52.26000  ? 370 TYR   B CD1 1 
ATOM   3024 C CD2 . TYR   B 1 156 ? -11.94995 -18.24354 -35.86948 1.000 54.35000  ? 370 TYR   B CD2 1 
ATOM   3025 C CE1 . TYR   B 1 156 ? -14.29736 -18.62060 -37.28379 1.000 53.14000  ? 370 TYR   B CE1 1 
ATOM   3026 C CE2 . TYR   B 1 156 ? -11.90634 -18.58846 -37.22151 1.000 56.41000  ? 370 TYR   B CE2 1 
ATOM   3027 C CZ  . TYR   B 1 156 ? -13.09154 -18.77049 -37.91616 1.000 52.43000  ? 370 TYR   B CZ  1 
ATOM   3028 O OH  . TYR   B 1 156 ? -13.07993 -19.10741 -39.23819 1.000 55.80000  ? 370 TYR   B OH  1 
ATOM   3029 N N   . MET   B 1 157 ? -11.14085 -19.59169 -32.49280 1.000 48.67000  ? 371 MET   B N   1 
ATOM   3030 C CA  . MET   B 1 157 ? -9.94784  -20.41561 -32.62221 1.000 50.98000  ? 371 MET   B CA  1 
ATOM   3031 C C   . MET   B 1 157 ? -10.07453 -21.71967 -31.84125 1.000 49.22000  ? 371 MET   B C   1 
ATOM   3032 O O   . MET   B 1 157 ? -9.63861  -22.77661 -32.31644 1.000 50.76000  ? 371 MET   B O   1 
ATOM   3033 C CB  . MET   B 1 157 ? -8.73474  -19.61557 -32.15354 1.000 50.68000  ? 371 MET   B CB  1 
ATOM   3034 C CG  . MET   B 1 157 ? -8.23312  -18.64748 -33.20263 1.000 50.21000  ? 371 MET   B CG  1 
ATOM   3035 S SD  . MET   B 1 157 ? -8.12757  -19.42038 -34.82771 1.000 51.56000  ? 371 MET   B SD  1 
ATOM   3036 C CE  . MET   B 1 157 ? -6.93839  -20.70433 -34.48614 1.000 47.09000  ? 371 MET   B CE  1 
ATOM   3037 N N   . ILE   B 1 158 ? -10.65617 -21.67277 -30.64507 1.000 45.38000  ? 372 ILE   B N   1 
ATOM   3038 C CA  . ILE   B 1 158 ? -10.83386 -22.90283 -29.87509 1.000 57.13000  ? 372 ILE   B CA  1 
ATOM   3039 C C   . ILE   B 1 158 ? -11.62304 -23.92583 -30.67591 1.000 57.01000  ? 372 ILE   B C   1 
ATOM   3040 O O   . ILE   B 1 158 ? -11.27698 -25.11780 -30.70608 1.000 53.71000  ? 372 ILE   B O   1 
ATOM   3041 C CB  . ILE   B 1 158 ? -11.51247 -22.60194 -28.52486 1.000 58.22000  ? 372 ILE   B CB  1 
ATOM   3042 C CG1 . ILE   B 1 158 ? -10.75831 -21.47194 -27.80103 1.000 56.91000  ? 372 ILE   B CG1 1 
ATOM   3043 C CG2 . ILE   B 1 158 ? -11.67614 -23.89000 -27.70089 1.000 47.26000  ? 372 ILE   B CG2 1 
ATOM   3044 C CD1 . ILE   B 1 158 ? -10.99588 -21.42204 -26.35195 1.000 49.38000  ? 372 ILE   B CD1 1 
ATOM   3045 N N   . ASN   B 1 159 ? -12.66928 -23.46885 -31.36356 1.000 55.59000  ? 373 ASN   B N   1 
ATOM   3046 C CA  . ASN   B 1 159 ? -13.48747 -24.36785 -32.16537 1.000 58.62000  ? 373 ASN   B CA  1 
ATOM   3047 C C   . ASN   B 1 159 ? -12.75682 -24.84273 -33.41362 1.000 56.84000  ? 373 ASN   B C   1 
ATOM   3048 O O   . ASN   B 1 159 ? -12.83287 -26.02572 -33.78566 1.000 54.52000  ? 373 ASN   B O   1 
ATOM   3049 C CB  . ASN   B 1 159 ? -14.78063 -23.67290 -32.56293 1.000 66.26000  ? 373 ASN   B CB  1 
ATOM   3050 C CG  . ASN   B 1 159 ? -15.95654 -24.56698 -32.41763 1.000 72.32000  ? 373 ASN   B CG  1 
ATOM   3051 O OD1 . ASN   B 1 159 ? -16.15018 -25.18405 -31.35960 1.000 79.73000  ? 373 ASN   B OD1 1 
ATOM   3052 N ND2 . ASN   B 1 159 ? -16.72086 -24.72396 -33.50540 1.000 67.40000  ? 373 ASN   B ND2 1 
ATOM   3053 N N   . PHE   B 1 160 ? -12.11209 -23.91365 -34.11876 1.000 52.30000  ? 374 PHE   B N   1 
ATOM   3054 C CA  . PHE   B 1 160 ? -11.27841 -24.28754 -35.25103 1.000 47.75000  ? 374 PHE   B CA  1 
ATOM   3055 C C   . PHE   B 1 160 ? -10.35623 -25.44251 -34.87738 1.000 52.95000  ? 374 PHE   B C   1 
ATOM   3056 O O   . PHE   B 1 160 ? -10.40536 -26.51848 -35.49043 1.000 53.39000  ? 374 PHE   B O   1 
ATOM   3057 C CB  . PHE   B 1 160 ? -10.46463 -23.07947 -35.72321 1.000 47.48000  ? 374 PHE   B CB  1 
ATOM   3058 C CG  . PHE   B 1 160 ? -9.69100  -23.33335 -36.99446 1.000 51.68000  ? 374 PHE   B CG  1 
ATOM   3059 C CD1 . PHE   B 1 160 ? -10.34037 -23.41331 -38.22227 1.000 41.78000  ? 374 PHE   B CD1 1 
ATOM   3060 C CD2 . PHE   B 1 160 ? -8.32097  -23.52527 -36.95389 1.000 48.76000  ? 374 PHE   B CD2 1 
ATOM   3061 C CE1 . PHE   B 1 160 ? -9.65070  -23.65621 -39.36149 1.000 41.30000  ? 374 PHE   B CE1 1 
ATOM   3062 C CE2 . PHE   B 1 160 ? -7.62031  -23.75516 -38.10711 1.000 49.26000  ? 374 PHE   B CE2 1 
ATOM   3063 C CZ  . PHE   B 1 160 ? -8.27867  -23.83013 -39.30492 1.000 49.57000  ? 374 PHE   B CZ  1 
ATOM   3064 N N   . ILE   B 1 161 ? -9.51293  -25.23352 -33.85162 1.000 54.55000  ? 375 ILE   B N   1 
ATOM   3065 C CA  . ILE   B 1 161 ? -8.65671  -26.30450 -33.33495 1.000 54.47000  ? 375 ILE   B CA  1 
ATOM   3066 C C   . ILE   B 1 161 ? -9.47756  -27.56356 -33.06177 1.000 55.46000  ? 375 ILE   B C   1 
ATOM   3067 O O   . ILE   B 1 161 ? -9.16865  -28.63651 -33.59193 1.000 52.19000  ? 375 ILE   B O   1 
ATOM   3068 C CB  . ILE   B 1 161 ? -7.88836  -25.83153 -32.08315 1.000 55.90000  ? 375 ILE   B CB  1 
ATOM   3069 C CG1 . ILE   B 1 161 ? -6.92653  -24.68045 -32.42938 1.000 49.72000  ? 375 ILE   B CG1 1 
ATOM   3070 C CG2 . ILE   B 1 161 ? -7.18107  -27.00453 -31.36443 1.000 48.65000  ? 375 ILE   B CG2 1 
ATOM   3071 C CD1 . ILE   B 1 161 ? -6.28619  -24.03549 -31.16953 1.000 49.20000  ? 375 ILE   B CD1 1 
ATOM   3072 N N   . HIS   B 1 162 ? -10.56132 -27.44367 -32.27043 1.000 53.42000  ? 376 HIS   B N   1 
ATOM   3073 C CA  . HIS   B 1 162 ? -11.44317 -28.58574 -31.99623 1.000 56.54000  ? 376 HIS   B CA  1 
ATOM   3074 C C   . HIS   B 1 162 ? -11.94652 -29.26269 -33.27512 1.000 60.29000  ? 376 HIS   B C   1 
ATOM   3075 O O   . HIS   B 1 162 ? -11.94048 -30.49769 -33.37119 1.000 59.87000  ? 376 HIS   B O   1 
ATOM   3076 C CB  . HIS   B 1 162 ? -12.63994 -28.15486 -31.14384 1.000 59.09000  ? 376 HIS   B CB  1 
ATOM   3077 C CG  . HIS   B 1 162 ? -12.34850 -28.03492 -29.68192 1.000 58.53000  ? 376 HIS   B CG  1 
ATOM   3078 N ND1 . HIS   B 1 162 ? -13.00431 -27.13301 -28.86967 1.000 58.65000  ? 376 HIS   B ND1 1 
ATOM   3079 C CD2 . HIS   B 1 162 ? -11.48422 -28.70292 -28.88223 1.000 64.22000  ? 376 HIS   B CD2 1 
ATOM   3080 C CE1 . HIS   B 1 162 ? -12.55093 -27.24505 -27.63182 1.000 62.24000  ? 376 HIS   B CE1 1 
ATOM   3081 N NE2 . HIS   B 1 162 ? -11.63086 -28.19300 -27.61115 1.000 66.75000  ? 376 HIS   B NE2 1 
ATOM   3082 N N   . LYS   B 1 163 ? -12.39487 -28.48266 -34.26894 1.000 54.07000  ? 377 LYS   B N   1 
ATOM   3083 C CA  . LYS   B 1 163 ? -12.83021 -29.10362 -35.51984 1.000 54.64000  ? 377 LYS   B CA  1 
ATOM   3084 C C   . LYS   B 1 163 ? -11.68139 -29.80451 -36.24323 1.000 56.07000  ? 377 LYS   B C   1 
ATOM   3085 O O   . LYS   B 1 163 ? -11.86849 -30.89749 -36.79024 1.000 63.71000  ? 377 LYS   B O   1 
ATOM   3086 C CB  . LYS   B 1 163 ? -13.50255 -28.07460 -36.42858 1.000 56.68000  ? 377 LYS   B CB  1 
ATOM   3087 C CG  . LYS   B 1 163 ? -14.94744 -27.74971 -36.01012 1.000 52.40000  ? 377 LYS   B CG  1 
ATOM   3088 C CD  . LYS   B 1 163 ? -15.47071 -26.48070 -36.66689 1.000 57.17000  ? 377 LYS   B CD  1 
ATOM   3089 C CE  . LYS   B 1 163 ? -15.99913 -26.73765 -38.07774 1.000 62.80000  ? 377 LYS   B CE  1 
ATOM   3090 N NZ  . LYS   B 1 163 ? -16.60837 -25.49766 -38.62748 1.000 66.05000  ? 377 LYS   B NZ  1 
ATOM   3091 N N   . LEU   B 1 164 ? -10.48543 -29.21144 -36.25756 1.000 50.54000  ? 378 LEU   B N   1 
ATOM   3092 C CA  . LEU   B 1 164 ? -9.38861  -29.86333 -36.96893 1.000 55.84000  ? 378 LEU   B CA  1 
ATOM   3093 C C   . LEU   B 1 164 ? -9.08335  -31.22735 -36.37110 1.000 61.95000  ? 378 LEU   B C   1 
ATOM   3094 O O   . LEU   B 1 164 ? -8.83852  -32.18729 -37.11023 1.000 63.22000  ? 378 LEU   B O   1 
ATOM   3095 C CB  . LEU   B 1 164 ? -8.12765  -29.01226 -36.95226 1.000 47.43000  ? 378 LEU   B CB  1 
ATOM   3096 C CG  . LEU   B 1 164 ? -8.11901  -27.82620 -37.89120 1.000 48.18000  ? 378 LEU   B CG  1 
ATOM   3097 C CD1 . LEU   B 1 164 ? -6.97894  -26.94716 -37.48349 1.000 49.94000  ? 378 LEU   B CD1 1 
ATOM   3098 C CD2 . LEU   B 1 164 ? -7.98442  -28.28011 -39.33326 1.000 52.17000  ? 378 LEU   B CD2 1 
ATOM   3099 N N   . LYS   B 1 165 ? -9.09394  -31.33543 -35.03210 1.000 60.26000  ? 379 LYS   B N   1 
ATOM   3100 C CA  . LYS   B 1 165 ? -8.71867  -32.59944 -34.39629 1.000 62.54000  ? 379 LYS   B CA  1 
ATOM   3101 C C   . LYS   B 1 165 ? -9.66173  -33.71547 -34.82307 1.000 67.29000  ? 379 LYS   B C   1 
ATOM   3102 O O   . LYS   B 1 165 ? -9.24871  -34.87244 -34.98126 1.000 68.17000  ? 379 LYS   B O   1 
ATOM   3103 C CB  . LYS   B 1 165 ? -8.69721  -32.47353 -32.86229 1.000 62.22000  ? 379 LYS   B CB  1 
ATOM   3104 C CG  . LYS   B 1 165 ? -8.25711  -31.10454 -32.26034 1.000 67.72000  ? 379 LYS   B CG  1 
ATOM   3105 C CD  . LYS   B 1 165 ? -7.93664  -31.13661 -30.72744 1.000 67.98000  ? 379 LYS   B CD  1 
ATOM   3106 C CE  . LYS   B 1 165 ? -6.50655  -30.67655 -30.33985 1.000 69.47000  ? 379 LYS   B CE  1 
ATOM   3107 N NZ  . LYS   B 1 165 ? -6.24209  -30.67662 -28.84193 1.000 58.36000  ? 379 LYS   B NZ  1 
ATOM   3108 N N   . HIS   B 1 166 ? -10.92382 -33.38053 -35.05867 1.000 63.88000  ? 380 HIS   B N   1 
ATOM   3109 C CA  . HIS   B 1 166 ? -11.90084 -34.42157 -35.29643 1.000 67.20000  ? 380 HIS   B CA  1 
ATOM   3110 C C   . HIS   B 1 166 ? -11.91425 -34.86849 -36.74645 1.000 62.71000  ? 380 HIS   B C   1 
ATOM   3111 O O   . HIS   B 1 166 ? -12.47128 -35.92351 -37.04734 1.000 68.97000  ? 380 HIS   B O   1 
ATOM   3112 C CB  . HIS   B 1 166 ? -13.27072 -33.93268 -34.83599 1.000 71.97000  ? 380 HIS   B CB  1 
ATOM   3113 C CG  . HIS   B 1 166 ? -13.34929 -33.71577 -33.35195 1.000 74.40000  ? 380 HIS   B CG  1 
ATOM   3114 N ND1 . HIS   B 1 166 ? -13.93618 -32.60084 -32.78871 1.000 76.44000  ? 380 HIS   B ND1 1 
ATOM   3115 C CD2 . HIS   B 1 166 ? -12.86893 -34.44980 -32.31514 1.000 76.60000  ? 380 HIS   B CD2 1 
ATOM   3116 C CE1 . HIS   B 1 166 ? -13.83578 -32.66691 -31.46974 1.000 76.86000  ? 380 HIS   B CE1 1 
ATOM   3117 N NE2 . HIS   B 1 166 ? -13.18862 -33.77789 -31.15700 1.000 76.86000  ? 380 HIS   B NE2 1 
ATOM   3118 N N   . LEU   B 1 167 ? -11.30257 -34.11240 -37.63859 1.000 61.29000  ? 381 LEU   B N   1 
ATOM   3119 C CA  . LEU   B 1 167 ? -11.13195 -34.59732 -38.99567 1.000 63.37000  ? 381 LEU   B CA  1 
ATOM   3120 C C   . LEU   B 1 167 ? -10.39186 -35.93427 -38.96998 1.000 61.77000  ? 381 LEU   B C   1 
ATOM   3121 O O   . LEU   B 1 167 ? -9.43962  -36.09526 -38.20427 1.000 62.60000  ? 381 LEU   B O   1 
ATOM   3122 C CB  . LEU   B 1 167 ? -10.37226 -33.57022 -39.83585 1.000 60.57000  ? 381 LEU   B CB  1 
ATOM   3123 C CG  . LEU   B 1 167 ? -11.13438 -32.25026 -39.96954 1.000 63.37000  ? 381 LEU   B CG  1 
ATOM   3124 C CD1 . LEU   B 1 167 ? -10.21559 -31.12318 -40.44775 1.000 58.64000  ? 381 LEU   B CD1 1 
ATOM   3125 C CD2 . LEU   B 1 167 ? -12.33066 -32.44927 -40.91419 1.000 50.41000  ? 381 LEU   B CD2 1 
ATOM   3126 N N   . PRO   B 1 168 ? -10.84004 -36.93026 -39.74190 1.000 63.15000  ? 382 PRO   B N   1 
ATOM   3127 C CA  . PRO   B 1 168 ? -10.18694 -38.24522 -39.67517 1.000 63.94000  ? 382 PRO   B CA  1 
ATOM   3128 C C   . PRO   B 1 168 ? -8.77011  -38.30611 -40.24061 1.000 69.26000  ? 382 PRO   B C   1 
ATOM   3129 O O   . PRO   B 1 168 ? -8.02494  -39.22108 -39.86488 1.000 69.47000  ? 382 PRO   B O   1 
ATOM   3130 C CB  . PRO   B 1 168 ? -11.15013 -39.15823 -40.45593 1.000 59.45000  ? 382 PRO   B CB  1 
ATOM   3131 C CG  . PRO   B 1 168 ? -12.12138 -38.26325 -41.12158 1.000 56.91000  ? 382 PRO   B CG  1 
ATOM   3132 C CD  . PRO   B 1 168 ? -12.20620 -37.04430 -40.28249 1.000 63.48000  ? 382 PRO   B CD  1 
ATOM   3133 N N   . GLU   B 1 169 ? -8.35143  -37.38803 -41.10968 1.000 68.10000  ? 383 GLU   B N   1 
ATOM   3134 C CA  . GLU   B 1 169 ? -7.04161  -37.52292 -41.74309 1.000 73.82000  ? 383 GLU   B CA  1 
ATOM   3135 C C   . GLU   B 1 169 ? -6.31870  -36.17587 -41.78423 1.000 72.94000  ? 383 GLU   B C   1 
ATOM   3136 O O   . GLU   B 1 169 ? -6.94475  -35.10791 -41.74198 1.000 69.32000  ? 383 GLU   B O   1 
ATOM   3137 C CB  . GLU   B 1 169 ? -7.17601  -38.10284 -43.16708 1.000 76.78000  ? 383 GLU   B CB  1 
ATOM   3138 C CG  . GLU   B 1 169 ? -7.75495  -39.53287 -43.22498 1.000 85.19000  ? 383 GLU   B CG  1 
ATOM   3139 C CD  . GLU   B 1 169 ? -6.82409  -40.53578 -43.88633 1.000 89.38000  ? 383 GLU   B CD  1 
ATOM   3140 O OE1 . GLU   B 1 169 ? -5.69592  -40.73575 -43.37368 1.000 90.87000  ? 383 GLU   B OE1 1 
ATOM   3141 O OE2 . GLU   B 1 169 ? -7.22337  -41.11775 -44.92424 1.000 84.02000  ? 383 GLU   B OE2 1 
ATOM   3142 N N   . LYS   B 1 170 ? -4.97673  -36.23779 -41.87564 1.000 71.63000  ? 384 LYS   B N   1 
ATOM   3143 C CA  . LYS   B 1 170 ? -4.17280  -35.01474 -41.87081 1.000 67.48000  ? 384 LYS   B CA  1 
ATOM   3144 C C   . LYS   B 1 170 ? -4.29724  -34.25868 -43.18773 1.000 66.42000  ? 384 LYS   B C   1 
ATOM   3145 O O   . LYS   B 1 170 ? -4.27432  -33.02267 -43.19067 1.000 67.32000  ? 384 LYS   B O   1 
ATOM   3146 C CB  . LYS   B 1 170 ? -2.69968  -35.30968 -41.54228 1.000 68.31000  ? 384 LYS   B CB  1 
ATOM   3147 C CG  . LYS   B 1 170 ? -2.49727  -36.25573 -40.36439 1.000 70.14000  ? 384 LYS   B CG  1 
ATOM   3148 C CD  . LYS   B 1 170 ? -2.31034  -37.68469 -40.86453 1.000 73.50000  ? 384 LYS   B CD  1 
ATOM   3149 C CE  . LYS   B 1 170 ? -2.41994  -38.75676 -39.76356 1.000 80.98000  ? 384 LYS   B CE  1 
ATOM   3150 N NZ  . LYS   B 1 170 ? -3.85584  -39.19286 -39.51615 1.000 74.23000  ? 384 LYS   B NZ  1 
ATOM   3151 N N   . TYR   B 1 171 ? -4.46154  -34.96062 -44.31572 1.000 58.52000  ? 385 TYR   B N   1 
ATOM   3152 C CA  . TYR   B 1 171 ? -4.61697  -34.22256 -45.56563 1.000 60.64000  ? 385 TYR   B CA  1 
ATOM   3153 C C   . TYR   B 1 171 ? -5.86600  -33.35063 -45.52220 1.000 63.11000  ? 385 TYR   B C   1 
ATOM   3154 O O   . TYR   B 1 171 ? -5.86423  -32.22060 -46.03514 1.000 63.10000  ? 385 TYR   B O   1 
ATOM   3155 C CB  . TYR   B 1 171 ? -4.61428  -35.17449 -46.77069 1.000 59.95000  ? 385 TYR   B CB  1 
ATOM   3156 C CG  . TYR   B 1 171 ? -5.88232  -35.93354 -47.05235 1.000 65.28000  ? 385 TYR   B CG  1 
ATOM   3157 C CD1 . TYR   B 1 171 ? -6.94556  -35.34557 -47.74499 1.000 61.78000  ? 385 TYR   B CD1 1 
ATOM   3158 C CD2 . TYR   B 1 171 ? -6.02111  -37.24558 -46.63038 1.000 69.82000  ? 385 TYR   B CD2 1 
ATOM   3159 C CE1 . TYR   B 1 171 ? -8.10860  -36.06162 -48.01068 1.000 62.18000  ? 385 TYR   B CE1 1 
ATOM   3160 C CE2 . TYR   B 1 171 ? -7.18115  -37.95963 -46.87707 1.000 75.90000  ? 385 TYR   B CE2 1 
ATOM   3161 C CZ  . TYR   B 1 171 ? -8.22239  -37.36965 -47.56872 1.000 70.60000  ? 385 TYR   B CZ  1 
ATOM   3162 O OH  . TYR   B 1 171 ? -9.36242  -38.10970 -47.80941 1.000 74.44000  ? 385 TYR   B OH  1 
ATOM   3163 N N   . MET   B 1 172 ? -6.93478  -33.84373 -44.88291 1.000 62.68000  ? 386 MET   B N   1 
ATOM   3164 C CA  . MET   B 1 172 ? -8.08575  -32.98681 -44.60451 1.000 61.46000  ? 386 MET   B CA  1 
ATOM   3165 C C   . MET   B 1 172 ? -7.68155  -31.81984 -43.71656 1.000 56.45000  ? 386 MET   B C   1 
ATOM   3166 O O   . MET   B 1 172 ? -8.00970  -30.66284 -44.01539 1.000 52.65000  ? 386 MET   B O   1 
ATOM   3167 C CB  . MET   B 1 172 ? -9.22551  -33.80792 -43.97821 1.000 58.82000  ? 386 MET   B CB  1 
ATOM   3168 C CG  . MET   B 1 172 ? -9.33359  -35.24489 -44.52326 1.000 67.05000  ? 386 MET   B CG  1 
ATOM   3169 S SD  . MET   B 1 172 ? -10.43927 -36.45000 -43.70999 1.000 68.19000  ? 386 MET   B SD  1 
ATOM   3170 C CE  . MET   B 1 172 ? -11.86120 -35.47911 -43.27350 1.000 62.29000  ? 386 MET   B CE  1 
ATOM   3171 N N   . MET   B 1 173 ? -6.92620  -32.09986 -42.64681 1.000 55.51000  ? 387 MET   B N   1 
ATOM   3172 C CA  . MET   B 1 173 ? -6.44100  -31.04288 -41.75989 1.000 57.43000  ? 387 MET   B CA  1 
ATOM   3173 C C   . MET   B 1 173 ? -5.54328  -30.06679 -42.50911 1.000 54.18000  ? 387 MET   B C   1 
ATOM   3174 O O   . MET   B 1 173 ? -5.63029  -28.84780 -42.31001 1.000 52.84000  ? 387 MET   B O   1 
ATOM   3175 C CB  . MET   B 1 173 ? -5.67560  -31.64491 -40.57716 1.000 60.34000  ? 387 MET   B CB  1 
ATOM   3176 C CG  . MET   B 1 173 ? -6.54525  -32.31102 -39.54093 1.000 57.18000  ? 387 MET   B CG  1 
ATOM   3177 S SD  . MET   B 1 173 ? -5.68777  -32.87605 -38.06023 1.000 62.08000  ? 387 MET   B SD  1 
ATOM   3178 C CE  . MET   B 1 173 ? -4.20191  -33.64393 -38.67972 1.000 65.87000  ? 387 MET   B CE  1 
ATOM   3179 N N   . ASN   B 1 174 ? -4.67151  -30.58469 -43.37540 1.000 53.79000  ? 388 ASN   B N   1 
ATOM   3180 C CA  . ASN   B 1 174 ? -3.84681  -29.69659 -44.17660 1.000 52.22000  ? 388 ASN   B CA  1 
ATOM   3181 C C   . ASN   B 1 174 ? -4.71212  -28.78559 -45.01729 1.000 52.11000  ? 388 ASN   B C   1 
ATOM   3182 O O   . ASN   B 1 174 ? -4.50420  -27.56358 -45.04328 1.000 51.36000  ? 388 ASN   B O   1 
ATOM   3183 C CB  . ASN   B 1 174 ? -2.89903  -30.50449 -45.06194 1.000 56.07000  ? 388 ASN   B CB  1 
ATOM   3184 C CG  . ASN   B 1 174 ? -1.45401  -30.05641 -44.91735 1.000 50.55000  ? 388 ASN   B CG  1 
ATOM   3185 O OD1 . ASN   B 1 174 ? -1.02071  -29.61745 -43.84146 1.000 49.37000  ? 388 ASN   B OD1 1 
ATOM   3186 N ND2 . ASN   B 1 174 ? -0.72134  -30.09630 -46.01958 1.000 53.65000  ? 388 ASN   B ND2 1 
ATOM   3187 N N   . SER   B 1 175 ? -5.71828  -29.36661 -45.68102 1.000 54.98000  ? 389 SER   B N   1 
ATOM   3188 C CA  . SER   B 1 175 ? -6.56361  -28.60961 -46.59372 1.000 53.29000  ? 389 SER   B CA  1 
ATOM   3189 C C   . SER   B 1 175 ? -7.30246  -27.48769 -45.88243 1.000 51.34000  ? 389 SER   B C   1 
ATOM   3190 O O   . SER   B 1 175 ? -7.36868  -26.36367 -46.39534 1.000 51.67000  ? 389 SER   B O   1 
ATOM   3191 C CB  . SER   B 1 175 ? -7.55476  -29.53763 -47.27947 1.000 52.20000  ? 389 SER   B CB  1 
ATOM   3192 O OG  . SER   B 1 175 ? -8.25811  -28.81361 -48.28321 1.000 59.02000  ? 389 SER   B OG  1 
ATOM   3193 N N   . VAL   B 1 176 ? -7.86908  -27.77080 -44.70727 1.000 50.53000  ? 390 VAL   B N   1 
ATOM   3194 C CA  . VAL   B 1 176 ? -8.51791  -26.71988 -43.92601 1.000 50.93000  ? 390 VAL   B CA  1 
ATOM   3195 C C   . VAL   B 1 176 ? -7.52586  -25.62584 -43.55225 1.000 51.19000  ? 390 VAL   B C   1 
ATOM   3196 O O   . VAL   B 1 176 ? -7.86793  -24.43586 -43.55408 1.000 54.66000  ? 390 VAL   B O   1 
ATOM   3197 C CB  . VAL   B 1 176 ? -9.21550  -27.31799 -42.68984 1.000 51.24000  ? 390 VAL   B CB  1 
ATOM   3198 C CG1 . VAL   B 1 176 ? -9.71728  -26.20707 -41.77162 1.000 39.47000  ? 390 VAL   B CG1 1 
ATOM   3199 C CG2 . VAL   B 1 176 ? -10.39959 -28.17003 -43.14852 1.000 47.11000  ? 390 VAL   B CG2 1 
ATOM   3200 N N   . LEU   B 1 177 ? -6.28274  -25.99579 -43.24165 1.000 49.87000  ? 391 LEU   B N   1 
ATOM   3201 C CA  . LEU   B 1 177 ? -5.30069  -24.98075 -42.87889 1.000 51.34000  ? 391 LEU   B CA  1 
ATOM   3202 C C   . LEU   B 1 177 ? -4.81310  -24.16865 -44.08499 1.000 49.26000  ? 391 LEU   B C   1 
ATOM   3203 O O   . LEU   B 1 177 ? -4.29411  -23.06063 -43.90208 1.000 48.90000  ? 391 LEU   B O   1 
ATOM   3204 C CB  . LEU   B 1 177 ? -4.13843  -25.66173 -42.15028 1.000 51.77000  ? 391 LEU   B CB  1 
ATOM   3205 C CG  . LEU   B 1 177 ? -4.47597  -26.19683 -40.74321 1.000 52.32000  ? 391 LEU   B CG  1 
ATOM   3206 C CD1 . LEU   B 1 177 ? -3.24973  -26.79479 -40.07262 1.000 48.07000  ? 391 LEU   B CD1 1 
ATOM   3207 C CD2 . LEU   B 1 177 ? -5.05477  -25.07791 -39.88497 1.000 47.69000  ? 391 LEU   B CD2 1 
ATOM   3208 N N   . GLU   B 1 178 ? -5.00145  -24.66359 -45.30996 1.000 44.58000  ? 392 GLU   B N   1 
ATOM   3209 C CA  . GLU   B 1 178 ? -4.46484  -23.95450 -46.46108 1.000 46.33000  ? 392 GLU   B CA  1 
ATOM   3210 C C   . GLU   B 1 178 ? -5.14499  -22.61352 -46.69780 1.000 49.97000  ? 392 GLU   B C   1 
ATOM   3211 O O   . GLU   B 1 178 ? -4.55823  -21.73445 -47.34393 1.000 46.87000  ? 392 GLU   B O   1 
ATOM   3212 C CB  . GLU   B 1 178 ? -4.60117  -24.80943 -47.71109 1.000 53.70000  ? 392 GLU   B CB  1 
ATOM   3213 C CG  . GLU   B 1 178 ? -3.39422  -25.62434 -48.03851 1.000 60.87000  ? 392 GLU   B CG  1 
ATOM   3214 C CD  . GLU   B 1 178 ? -3.65951  -26.57429 -49.18448 1.000 67.57000  ? 392 GLU   B CD  1 
ATOM   3215 O OE1 . GLU   B 1 178 ? -4.58377  -26.28030 -49.99118 1.000 53.32000  ? 392 GLU   B OE1 1 
ATOM   3216 O OE2 . GLU   B 1 178 ? -2.93048  -27.60024 -49.26576 1.000 73.79000  ? 392 GLU   B OE2 1 
ATOM   3217 N N   . ASN   B 1 179 ? -6.37185  -22.44862 -46.20842 1.000 50.01000  ? 393 ASN   B N   1 
ATOM   3218 C CA  . ASN   B 1 179 ? -7.13397  -21.21666 -46.36912 1.000 53.70000  ? 393 ASN   B CA  1 
ATOM   3219 C C   . ASN   B 1 179 ? -7.21662  -20.43874 -45.06905 1.000 52.14000  ? 393 ASN   B C   1 
ATOM   3220 O O   . ASN   B 1 179 ? -7.85766  -19.37878 -45.01579 1.000 54.81000  ? 393 ASN   B O   1 
ATOM   3221 C CB  . ASN   B 1 179 ? -8.54710  -21.53871 -46.87070 1.000 52.18000  ? 393 ASN   B CB  1 
ATOM   3222 C CG  . ASN   B 1 179 ? -8.55434  -22.68265 -47.85777 1.000 53.75000  ? 393 ASN   B CG  1 
ATOM   3223 O OD1 . ASN   B 1 179 ? -8.99717  -23.80070 -47.53270 1.000 50.52000  ? 393 ASN   B OD1 1 
ATOM   3224 N ND2 . ASN   B 1 179 ? -8.03672  -22.42855 -49.06091 1.000 47.35000  ? 393 ASN   B ND2 1 
ATOM   3225 N N   . PHE   B 1 180 ? -6.61227  -20.96476 -44.01826 1.000 51.14000  ? 394 PHE   B N   1 
ATOM   3226 C CA  . PHE   B 1 180 ? -6.53292  -20.30483 -42.73125 1.000 47.33000  ? 394 PHE   B CA  1 
ATOM   3227 C C   . PHE   B 1 180 ? -5.23195  -19.50576 -42.68459 1.000 47.35000  ? 394 PHE   B C   1 
ATOM   3228 O O   . PHE   B 1 180 ? -4.16501  -20.05368 -42.97895 1.000 49.85000  ? 394 PHE   B O   1 
ATOM   3229 C CB  . PHE   B 1 180 ? -6.59052  -21.36490 -41.63529 1.000 50.08000  ? 394 PHE   B CB  1 
ATOM   3230 C CG  . PHE   B 1 180 ? -6.33814  -20.82796 -40.26533 1.000 53.50000  ? 394 PHE   B CG  1 
ATOM   3231 C CD1 . PHE   B 1 180 ? -7.31998  -20.12106 -39.60400 1.000 44.62000  ? 394 PHE   B CD1 1 
ATOM   3232 C CD2 . PHE   B 1 180 ? -5.11594  -21.02493 -39.64872 1.000 45.43000  ? 394 PHE   B CD2 1 
ATOM   3233 C CE1 . PHE   B 1 180 ? -7.08963  -19.63212 -38.36004 1.000 50.30000  ? 394 PHE   B CE1 1 
ATOM   3234 C CE2 . PHE   B 1 180 ? -4.88559  -20.52399 -38.41376 1.000 46.38000  ? 394 PHE   B CE2 1 
ATOM   3235 C CZ  . PHE   B 1 180 ? -5.87243  -19.82508 -37.75942 1.000 50.94000  ? 394 PHE   B CZ  1 
ATOM   3236 N N   . THR   B 1 181 ? -5.32093  -18.20778 -42.37649 1.000 45.12000  ? 395 THR   B N   1 
ATOM   3237 C CA  . THR   B 1 181 ? -4.13893  -17.36472 -42.22180 1.000 41.62000  ? 395 THR   B CA  1 
ATOM   3238 C C   . THR   B 1 181 ? -4.35866  -16.34480 -41.11868 1.000 50.25000  ? 395 THR   B C   1 
ATOM   3239 O O   . THR   B 1 181 ? -5.49158  -15.96988 -40.80531 1.000 54.20000  ? 395 THR   B O   1 
ATOM   3240 C CB  . THR   B 1 181 ? -3.79135  -16.54563 -43.44986 1.000 39.02000  ? 395 THR   B CB  1 
ATOM   3241 O OG1 . THR   B 1 181 ? -4.90549  -15.70168 -43.74347 1.000 46.28000  ? 395 THR   B OG1 1 
ATOM   3242 C CG2 . THR   B 1 181 ? -3.47166  -17.42754 -44.62701 1.000 37.04000  ? 395 THR   B CG2 1 
ATOM   3243 N N   . ILE   B 1 182 ? -3.25352  -15.84477 -40.57398 1.000 49.01000  ? 396 ILE   B N   1 
ATOM   3244 C CA  . ILE   B 1 182 ? -3.28727  -14.81783 -39.54391 1.000 42.84000  ? 396 ILE   B CA  1 
ATOM   3245 C C   . ILE   B 1 182 ? -2.32944  -13.69175 -39.90614 1.000 45.69000  ? 396 ILE   B C   1 
ATOM   3246 O O   . ILE   B 1 182 ? -1.19056  -13.93166 -40.33050 1.000 47.61000  ? 396 ILE   B O   1 
ATOM   3247 C CB  . ILE   B 1 182 ? -2.92282  -15.39788 -38.18006 1.000 36.65000  ? 396 ILE   B CB  1 
ATOM   3248 C CG1 . ILE   B 1 182 ? -3.79166  -16.61195 -37.89786 1.000 42.37000  ? 396 ILE   B CG1 1 
ATOM   3249 C CG2 . ILE   B 1 182 ? -3.11457  -14.34195 -37.16394 1.000 39.19000  ? 396 ILE   B CG2 1 
ATOM   3250 C CD1 . ILE   B 1 182 ? -3.52523  -17.24201 -36.58898 1.000 44.61000  ? 396 ILE   B CD1 1 
ATOM   3251 N N   . LEU   B 1 183 ? -2.78146  -12.46179 -39.72593 1.000 40.51000  ? 397 LEU   B N   1 
ATOM   3252 C CA  . LEU   B 1 183 ? -1.93759  -11.30073 -39.94612 1.000 41.59000  ? 397 LEU   B CA  1 
ATOM   3253 C C   . LEU   B 1 183 ? -1.77523  -10.57979 -38.62213 1.000 43.45000  ? 397 LEU   B C   1 
ATOM   3254 O O   . LEU   B 1 183 ? -2.76707  -10.18389 -38.00180 1.000 39.65000  ? 397 LEU   B O   1 
ATOM   3255 C CB  . LEU   B 1 183 ? -2.52797  -10.35970 -40.99189 1.000 43.71000  ? 397 LEU   B CB  1 
ATOM   3256 C CG  . LEU   B 1 183 ? -1.57418  -9.25962  -41.47111 1.000 47.18000  ? 397 LEU   B CG  1 
ATOM   3257 C CD1 . LEU   B 1 183 ? -0.57647  -9.77250  -42.53145 1.000 46.19000  ? 397 LEU   B CD1 1 
ATOM   3258 C CD2 . LEU   B 1 183 ? -2.36640  -8.04363  -41.96980 1.000 45.50000  ? 397 LEU   B CD2 1 
ATOM   3259 N N   . GLN   B 1 184 ? -0.53611  -10.41975 -38.18650 1.000 45.42000  ? 398 GLN   B N   1 
ATOM   3260 C CA  . GLN   B 1 184 ? -0.24380  -9.62080  -37.01454 1.000 42.69000  ? 398 GLN   B CA  1 
ATOM   3261 C C   . GLN   B 1 184 ? 0.42899   -8.33073  -37.46767 1.000 45.22000  ? 398 GLN   B C   1 
ATOM   3262 O O   . GLN   B 1 184 ? 1.38375   -8.35563  -38.26096 1.000 44.55000  ? 398 GLN   B O   1 
ATOM   3263 C CB  . GLN   B 1 184 ? 0.61954   -10.38980 -36.03384 1.000 41.91000  ? 398 GLN   B CB  1 
ATOM   3264 C CG  . GLN   B 1 184 ? 0.95786   -9.57585  -34.82790 1.000 45.19000  ? 398 GLN   B CG  1 
ATOM   3265 C CD  . GLN   B 1 184 ? 1.76420   -10.36686 -33.84519 1.000 51.33000  ? 398 GLN   B CD  1 
ATOM   3266 O OE1 . GLN   B 1 184 ? 2.79632   -9.90183  -33.36748 1.000 49.51000  ? 398 GLN   B OE1 1 
ATOM   3267 N NE2 . GLN   B 1 184 ? 1.30437   -11.58191 -33.53012 1.000 51.00000  ? 398 GLN   B NE2 1 
ATOM   3268 N N   . VAL   B 1 185 ? -0.11494  -7.20979  -37.00944 1.000 43.92000  ? 399 VAL   B N   1 
ATOM   3269 C CA  . VAL   B 1 185 ? 0.39889   -5.87774  -37.30552 1.000 45.06000  ? 399 VAL   B CA  1 
ATOM   3270 C C   . VAL   B 1 185 ? 0.60827   -5.21881  -35.94954 1.000 49.04000  ? 399 VAL   B C   1 
ATOM   3271 O O   . VAL   B 1 185 ? -0.36453  -4.94191  -35.22323 1.000 42.09000  ? 399 VAL   B O   1 
ATOM   3272 C CB  . VAL   B 1 185 ? -0.56242  -5.05275  -38.18318 1.000 44.74000  ? 399 VAL   B CB  1 
ATOM   3273 C CG1 . VAL   B 1 185 ? -0.00958  -3.66770  -38.42527 1.000 43.03000  ? 399 VAL   B CG1 1 
ATOM   3274 C CG2 . VAL   B 1 185 ? -0.88778  -5.76169  -39.51012 1.000 41.62000  ? 399 VAL   B CG2 1 
ATOM   3275 N N   . VAL   B 1 186 ? 1.87236   -5.01676  -35.58491 1.000 44.93000  ? 400 VAL   B N   1 
ATOM   3276 C CA  . VAL   B 1 186 ? 2.22870   -4.31581  -34.35898 1.000 47.65000  ? 400 VAL   B CA  1 
ATOM   3277 C C   . VAL   B 1 186 ? 2.56950   -2.88076  -34.72200 1.000 48.50000  ? 400 VAL   B C   1 
ATOM   3278 O O   . VAL   B 1 186 ? 3.28919   -2.62967  -35.70021 1.000 43.94000  ? 400 VAL   B O   1 
ATOM   3279 C CB  . VAL   B 1 186 ? 3.40296   -4.99278  -33.62138 1.000 43.67000  ? 400 VAL   B CB  1 
ATOM   3280 C CG1 . VAL   B 1 186 ? 3.60433   -4.32885  -32.28040 1.000 41.39000  ? 400 VAL   B CG1 1 
ATOM   3281 C CG2 . VAL   B 1 186 ? 3.15109   -6.47880  -33.46139 1.000 39.15000  ? 400 VAL   B CG2 1 
ATOM   3282 N N   . THR   B 1 187 ? 2.02668   -1.94684  -33.95778 1.000 50.23000  ? 401 THR   B N   1 
ATOM   3283 C CA  . THR   B 1 187 ? 2.23952   -0.53781  -34.21777 1.000 55.71000  ? 401 THR   B CA  1 
ATOM   3284 C C   . THR   B 1 187 ? 2.45886   0.21413   -32.94679 1.000 54.36000  ? 401 THR   B C   1 
ATOM   3285 O O   . THR   B 1 187 ? 1.90419   -0.13197  -31.92164 1.000 54.37000  ? 401 THR   B O   1 
ATOM   3286 C CB  . THR   B 1 187 ? 1.00328   0.08815   -34.88336 1.000 55.99000  ? 401 THR   B CB  1 
ATOM   3287 O OG1 . THR   B 1 187 ? -0.17649  -0.35095  -34.20602 1.000 53.92000  ? 401 THR   B OG1 1 
ATOM   3288 C CG2 . THR   B 1 187 ? 0.91786   -0.31677  -36.33635 1.000 50.65000  ? 401 THR   B CG2 1 
ATOM   3289 N N   . SER   B 1 188 ? 3.28079   1.24418   -32.99498 1.000 56.74000  ? 402 SER   B N   1 
ATOM   3290 C CA  . SER   B 1 188 ? 3.41110   2.06112   -31.82097 1.000 63.34000  ? 402 SER   B CA  1 
ATOM   3291 C C   . SER   B 1 188 ? 2.10809   2.75603   -31.71354 1.000 64.20000  ? 402 SER   B C   1 
ATOM   3292 O O   . SER   B 1 188 ? 1.64076   3.35906   -32.66136 1.000 69.86000  ? 402 SER   B O   1 
ATOM   3293 C CB  . SER   B 1 188 ? 4.50098   3.09219   -31.99924 1.000 63.82000  ? 402 SER   B CB  1 
ATOM   3294 O OG  . SER   B 1 188 ? 4.40422   4.11313   -31.02616 1.000 73.82000  ? 402 SER   B OG  1 
ATOM   3295 N N   . ARG   B 1 189 ? 1.52545   2.72693   -30.53936 1.000 61.98000  ? 403 ARG   B N   1 
ATOM   3296 C CA  . ARG   B 1 189 ? 0.22844   3.29985   -30.43693 1.000 71.21000  ? 403 ARG   B CA  1 
ATOM   3297 C C   . ARG   B 1 189 ? 0.21628   4.78387   -30.69885 1.000 77.64000  ? 403 ARG   B C   1 
ATOM   3298 O O   . ARG   B 1 189 ? -0.66396  5.27685   -31.39055 1.000 74.64000  ? 403 ARG   B O   1 
ATOM   3299 C CB  . ARG   B 1 189 ? -0.30712  3.03474   -29.03479 1.000 66.42000  ? 403 ARG   B CB  1 
ATOM   3300 C CG  . ARG   B 1 189 ? -1.79608  3.24764   -28.87432 1.000 66.10000  ? 403 ARG   B CG  1 
ATOM   3301 C CD  . ARG   B 1 189 ? -2.14464  3.30954   -27.40321 1.000 71.09000  ? 403 ARG   B CD  1 
ATOM   3302 N NE  . ARG   B 1 189 ? -1.37950  4.36154   -26.74838 1.000 80.86000  ? 403 ARG   B NE  1 
ATOM   3303 C CZ  . ARG   B 1 189 ? -1.37311  4.57647   -25.43937 1.000 80.85000  ? 403 ARG   B CZ  1 
ATOM   3304 N NH1 . ARG   B 1 189 ? -2.08982  3.80538   -24.63620 1.000 79.00000  ? 403 ARG   B NH1 1 
ATOM   3305 N NH2 . ARG   B 1 189 ? -0.64302  5.55948   -24.93454 1.000 80.97000  ? 403 ARG   B NH2 1 
ATOM   3306 N N   . ASP   B 1 190 ? 1.16541   5.51289   -30.13009 1.000 76.14000  ? 404 ASP   B N   1 
ATOM   3307 C CA  . ASP   B 1 190 ? 1.21123   6.92791   -30.43102 1.000 80.26000  ? 404 ASP   B CA  1 
ATOM   3308 C C   . ASP   B 1 190 ? 1.55278   7.37201   -31.84310 1.000 87.74000  ? 404 ASP   B C   1 
ATOM   3309 O O   . ASP   B 1 190 ? 0.84356   8.19500   -32.40884 1.000 89.42000  ? 404 ASP   B O   1 
ATOM   3310 C CB  . ASP   B 1 190 ? 2.27048   7.53492   -29.51831 1.000 83.83000  ? 404 ASP   B CB  1 
ATOM   3311 C CG  . ASP   B 1 190 ? 2.22794   6.96383   -28.11533 1.000 93.45000  ? 404 ASP   B CG  1 
ATOM   3312 O OD1 . ASP   B 1 190 ? 1.13110   6.57474   -27.66002 1.000 90.87000  ? 404 ASP   B OD1 1 
ATOM   3313 O OD2 . ASP   B 1 190 ? 3.29214   6.90786   -27.46566 1.000 90.26000  ? 404 ASP   B OD2 1 
ATOM   3314 N N   . SER   B 1 191 ? 2.59463   6.80310   -32.43645 1.000 82.42000  ? 405 SER   B N   1 
ATOM   3315 C CA  . SER   B 1 191 ? 2.95019   7.10021   -33.82754 1.000 77.87000  ? 405 SER   B CA  1 
ATOM   3316 C C   . SER   B 1 191 ? 1.91294   6.58720   -34.76526 1.000 75.86000  ? 405 SER   B C   1 
ATOM   3317 O O   . SER   B 1 191 ? 1.63859   7.21224   -35.77614 1.000 81.31000  ? 405 SER   B O   1 
ATOM   3318 C CB  . SER   B 1 191 ? 4.32512   6.55431   -34.18399 1.000 73.63000  ? 405 SER   B CB  1 
ATOM   3319 O OG  . SER   B 1 191 ? 4.33322   5.14930   -34.10507 1.000 74.43000  ? 405 SER   B OG  1 
ATOM   3320 N N   . GLN   B 1 192 ? 1.39810   5.40315   -34.46417 1.000 80.97000  ? 406 GLN   B N   1 
ATOM   3321 C CA  . GLN   B 1 192 ? 0.45887   4.72515   -35.34392 1.000 76.73000  ? 406 GLN   B CA  1 
ATOM   3322 C C   . GLN   B 1 192 ? 1.33757   4.14526   -36.43622 1.000 67.97000  ? 406 GLN   B C   1 
ATOM   3323 O O   . GLN   B 1 192 ? 0.84930   3.63329   -37.42610 1.000 75.66000  ? 406 GLN   B O   1 
ATOM   3324 C CB  . GLN   B 1 192 ? -0.66334  5.63011   -35.84553 1.000 73.81000  ? 406 GLN   B CB  1 
ATOM   3325 C CG  . GLN   B 1 192 ? -1.92640  4.87506   -36.20419 1.000 74.75000  ? 406 GLN   B CG  1 
ATOM   3326 C CD  . GLN   B 1 192 ? -2.97364  5.76403   -36.83682 1.000 87.05000  ? 406 GLN   B CD  1 
ATOM   3327 O OE1 . GLN   B 1 192 ? -2.77176  6.96706   -36.99581 1.000 86.91000  ? 406 GLN   B OE1 1 
ATOM   3328 N NE2 . GLN   B 1 192 ? -4.10172  5.17299   -37.20651 1.000 90.05000  ? 406 GLN   B NE2 1 
ATOM   3329 N N   . GLU   B 1 193 ? 2.64163   4.19233   -36.22862 1.000 66.43000  ? 407 GLU   B N   1 
ATOM   3330 C CA  . GLU   B 1 193 ? 3.57236   3.69344   -37.20893 1.000 66.32000  ? 407 GLU   B CA  1 
ATOM   3331 C C   . GLU   B 1 193 ? 3.70747   2.20144   -37.15806 1.000 65.07000  ? 407 GLU   B C   1 
ATOM   3332 O O   . GLU   B 1 193 ? 3.63182   1.59738   -36.10107 1.000 62.40000  ? 407 GLU   B O   1 
ATOM   3333 C CB  . GLU   B 1 193 ? 4.94040   4.30850   -36.96531 1.000 69.51000  ? 407 GLU   B CB  1 
ATOM   3334 C CG  . GLU   B 1 193 ? 6.08422   3.63561   -37.70869 1.000 72.52000  ? 407 GLU   B CG  1 
ATOM   3335 C CD  . GLU   B 1 193 ? 7.44138   3.94266   -37.11109 1.000 74.06000  ? 407 GLU   B CD  1 
ATOM   3336 O OE1 . GLU   B 1 193 ? 7.54157   4.88162   -36.29707 1.000 69.47000  ? 407 GLU   B OE1 1 
ATOM   3337 O OE2 . GLU   B 1 193 ? 8.41431   3.24273   -37.45942 1.000 73.39000  ? 407 GLU   B OE2 1 
ATOM   3338 N N   . THR   B 1 194 ? 3.93415   1.60552   -38.31416 1.000 64.01000  ? 408 THR   B N   1 
ATOM   3339 C CA  . THR   B 1 194 ? 4.06521   0.15253   -38.38928 1.000 59.17000  ? 408 THR   B CA  1 
ATOM   3340 C C   . THR   B 1 194 ? 5.45839   -0.27741  -37.89773 1.000 58.77000  ? 408 THR   B C   1 
ATOM   3341 O O   . THR   B 1 194 ? 6.48119   0.13968   -38.45702 1.000 53.29000  ? 408 THR   B O   1 
ATOM   3342 C CB  . THR   B 1 194 ? 3.82980   -0.32640  -39.82124 1.000 53.95000  ? 408 THR   B CB  1 
ATOM   3343 O OG1 . THR   B 1 194 ? 2.57763   0.17656   -40.31283 1.000 59.32000  ? 408 THR   B OG1 1 
ATOM   3344 C CG2 . THR   B 1 194 ? 3.82488   -1.82539  -39.86632 1.000 45.64000  ? 408 THR   B CG2 1 
ATOM   3345 N N   . LEU   B 1 195 ? 5.49875   -1.12047  -36.86079 1.000 48.87000  ? 409 LEU   B N   1 
ATOM   3346 C CA  . LEU   B 1 195 ? 6.75895   -1.58843  -36.30420 1.000 48.46000  ? 409 LEU   B CA  1 
ATOM   3347 C C   . LEU   B 1 195 ? 7.10590   -3.00338  -36.71839 1.000 46.75000  ? 409 LEU   B C   1 
ATOM   3348 O O   . LEU   B 1 195 ? 8.28393   -3.36032  -36.70977 1.000 46.96000  ? 409 LEU   B O   1 
ATOM   3349 C CB  . LEU   B 1 195 ? 6.74241   -1.52852  -34.76719 1.000 52.69000  ? 409 LEU   B CB  1 
ATOM   3350 C CG  . LEU   B 1 195 ? 6.13658   -0.35460  -33.99594 1.000 54.41000  ? 409 LEU   B CG  1 
ATOM   3351 C CD1 . LEU   B 1 195 ? 6.08204   -0.71469  -32.54694 1.000 51.35000  ? 409 LEU   B CD1 1 
ATOM   3352 C CD2 . LEU   B 1 195 ? 6.97444   0.88346   -34.19212 1.000 60.06000  ? 409 LEU   B CD2 1 
ATOM   3353 N N   . LEU   B 1 196 ? 6.10885   -3.81642  -37.05513 1.000 48.82000  ? 410 LEU   B N   1 
ATOM   3354 C CA  . LEU   B 1 196 ? 6.32983   -5.21839  -37.39728 1.000 45.79000  ? 410 LEU   B CA  1 
ATOM   3355 C C   . LEU   B 1 196 ? 5.05069   -5.82143  -37.95493 1.000 47.04000  ? 410 LEU   B C   1 
ATOM   3356 O O   . LEU   B 1 196 ? 3.98687   -5.70053  -37.33360 1.000 51.46000  ? 410 LEU   B O   1 
ATOM   3357 C CB  . LEU   B 1 196 ? 6.80724   -6.01343  -36.17947 1.000 43.22000  ? 410 LEU   B CB  1 
ATOM   3358 C CG  . LEU   B 1 196 ? 7.38622   -7.38538  -36.50773 1.000 45.97000  ? 410 LEU   B CG  1 
ATOM   3359 C CD1 . LEU   B 1 196 ? 8.74701   -7.21026  -37.16813 1.000 47.05000  ? 410 LEU   B CD1 1 
ATOM   3360 C CD2 . LEU   B 1 196 ? 7.50765   -8.19745  -35.25481 1.000 43.82000  ? 410 LEU   B CD2 1 
ATOM   3361 N N   . VAL   B 1 197 ? 5.12837   -6.43836  -39.13199 1.000 46.55000  ? 411 VAL   B N   1 
ATOM   3362 C CA  . VAL   B 1 197 ? 4.00523   -7.14639  -39.74169 1.000 46.79000  ? 411 VAL   B CA  1 
ATOM   3363 C C   . VAL   B 1 197 ? 4.44525   -8.58535  -39.95290 1.000 45.23000  ? 411 VAL   B C   1 
ATOM   3364 O O   . VAL   B 1 197 ? 5.45306   -8.83926  -40.62822 1.000 44.43000  ? 411 VAL   B O   1 
ATOM   3365 C CB  . VAL   B 1 197 ? 3.58078   -6.52334  -41.08152 1.000 49.51000  ? 411 VAL   B CB  1 
ATOM   3366 C CG1 . VAL   B 1 197 ? 2.34365   -7.23538  -41.64219 1.000 46.86000  ? 411 VAL   B CG1 1 
ATOM   3367 C CG2 . VAL   B 1 197 ? 3.36674   -5.04236  -40.94737 1.000 47.72000  ? 411 VAL   B CG2 1 
ATOM   3368 N N   . ILE   B 1 198 ? 3.69947   -9.52743  -39.39473 1.000 41.20000  ? 412 ILE   B N   1 
ATOM   3369 C CA  . ILE   B 1 198 ? 3.93447   -10.94040 -39.65088 1.000 40.21000  ? 412 ILE   B CA  1 
ATOM   3370 C C   . ILE   B 1 198 ? 2.67532   -11.52744 -40.27154 1.000 44.47000  ? 412 ILE   B C   1 
ATOM   3371 O O   . ILE   B 1 198 ? 1.58449   -11.43553 -39.69320 1.000 43.66000  ? 412 ILE   B O   1 
ATOM   3372 C CB  . ILE   B 1 198 ? 4.31191   -11.71645 -38.37604 1.000 41.53000  ? 412 ILE   B CB  1 
ATOM   3373 C CG1 . ILE   B 1 198 ? 5.43510   -11.01743 -37.60534 1.000 43.74000  ? 412 ILE   B CG1 1 
ATOM   3374 C CG2 . ILE   B 1 198 ? 4.68288   -13.14741 -38.74724 1.000 43.36000  ? 412 ILE   B CG2 1 
ATOM   3375 C CD1 . ILE   B 1 198 ? 5.84452   -11.72948 -36.35951 1.000 39.05000  ? 412 ILE   B CD1 1 
ATOM   3376 N N   . ALA   B 1 199 ? 2.82300   -12.12936 -41.44661 1.000 40.92000  ? 413 ALA   B N   1 
ATOM   3377 C CA  . ALA   B 1 199 ? 1.74886   -12.91539 -42.04433 1.000 40.53000  ? 413 ALA   B CA  1 
ATOM   3378 C C   . ALA   B 1 199 ? 2.01804   -14.38439 -41.74150 1.000 39.57000  ? 413 ALA   B C   1 
ATOM   3379 O O   . ALA   B 1 199 ? 3.13200   -14.86331 -41.95287 1.000 37.62000  ? 413 ALA   B O   1 
ATOM   3380 C CB  . ALA   B 1 199 ? 1.65339   -12.66731 -43.55029 1.000 32.21000  ? 413 ALA   B CB  1 
ATOM   3381 N N   . PHE   B 1 200 ? 1.02024   -15.08748 -41.20724 1.000 40.00000  ? 414 PHE   B N   1 
ATOM   3382 C CA  . PHE   B 1 200 ? 1.19745   -16.47649 -40.79337 1.000 39.93000  ? 414 PHE   B CA  1 
ATOM   3383 C C   . PHE   B 1 200 ? 0.36823   -17.38549 -41.68117 1.000 38.71000  ? 414 PHE   B C   1 
ATOM   3384 O O   . PHE   B 1 200 ? -0.81585  -17.12255 -41.90080 1.000 39.73000  ? 414 PHE   B O   1 
ATOM   3385 C CB  . PHE   B 1 200 ? 0.76690   -16.71560 -39.34326 1.000 39.92000  ? 414 PHE   B CB  1 
ATOM   3386 C CG  . PHE   B 1 200 ? 1.55817   -15.98362 -38.32245 1.000 36.15000  ? 414 PHE   B CG  1 
ATOM   3387 C CD1 . PHE   B 1 200 ? 2.75035   -16.49557 -37.84084 1.000 34.90000  ? 414 PHE   B CD1 1 
ATOM   3388 C CD2 . PHE   B 1 200 ? 1.06926   -14.79567 -37.79424 1.000 43.00000  ? 414 PHE   B CD2 1 
ATOM   3389 C CE1 . PHE   B 1 200 ? 3.45161   -15.83959 -36.84902 1.000 43.81000  ? 414 PHE   B CE1 1 
ATOM   3390 C CE2 . PHE   B 1 200 ? 1.76753   -14.11169 -36.79541 1.000 47.74000  ? 414 PHE   B CE2 1 
ATOM   3391 C CZ  . PHE   B 1 200 ? 2.95570   -14.63865 -36.30980 1.000 48.76000  ? 414 PHE   B CZ  1 
ATOM   3392 N N   . VAL   B 1 201 ? 0.97016   -18.47943 -42.14442 1.000 38.18000  ? 415 VAL   B N   1 
ATOM   3393 C CA  . VAL   B 1 201 ? 0.26898   -19.49442 -42.91926 1.000 46.43000  ? 415 VAL   B CA  1 
ATOM   3394 C C   . VAL   B 1 201 ? 0.65724   -20.84644 -42.32746 1.000 43.15000  ? 415 VAL   B C   1 
ATOM   3395 O O   . VAL   B 1 201 ? 1.66945   -20.96942 -41.64078 1.000 39.08000  ? 415 VAL   B O   1 
ATOM   3396 C CB  . VAL   B 1 201 ? 0.58851   -19.41332 -44.43836 1.000 37.47000  ? 415 VAL   B CB  1 
ATOM   3397 C CG1 . VAL   B 1 201 ? 0.47428   -17.96530 -44.93824 1.000 32.60000  ? 415 VAL   B CG1 1 
ATOM   3398 C CG2 . VAL   B 1 201 ? 1.93445   -20.01022 -44.75680 1.000 34.82000  ? 415 VAL   B CG2 1 
ATOM   3399 N N   . PHE   B 1 202 ? -0.15778  -21.87147 -42.58727 1.000 43.83000  ? 416 PHE   B N   1 
ATOM   3400 C CA  . PHE   B 1 202 ? -0.08746  -23.06851 -41.76336 1.000 41.00000  ? 416 PHE   B CA  1 
ATOM   3401 C C   . PHE   B 1 202 ? -0.19564  -24.35147 -42.59240 1.000 42.33000  ? 416 PHE   B C   1 
ATOM   3402 O O   . PHE   B 1 202 ? -0.73197  -24.37144 -43.69924 1.000 38.60000  ? 416 PHE   B O   1 
ATOM   3403 C CB  . PHE   B 1 202 ? -1.19214  -23.03364 -40.69103 1.000 36.65000  ? 416 PHE   B CB  1 
ATOM   3404 C CG  . PHE   B 1 202 ? -1.07191  -21.87869 -39.70499 1.000 40.51000  ? 416 PHE   B CG  1 
ATOM   3405 C CD1 . PHE   B 1 202 ? -1.46608  -20.59169 -40.04980 1.000 40.09000  ? 416 PHE   B CD1 1 
ATOM   3406 C CD2 . PHE   B 1 202 ? -0.60350  -22.09774 -38.40715 1.000 42.27000  ? 416 PHE   B CD2 1 
ATOM   3407 C CE1 . PHE   B 1 202 ? -1.35787  -19.54174 -39.13977 1.000 38.73000  ? 416 PHE   B CE1 1 
ATOM   3408 C CE2 . PHE   B 1 202 ? -0.50728  -21.05078 -37.49812 1.000 43.58000  ? 416 PHE   B CE2 1 
ATOM   3409 C CZ  . PHE   B 1 202 ? -0.88547  -19.77178 -37.87393 1.000 40.73000  ? 416 PHE   B CZ  1 
ATOM   3410 N N   . GLU   B 1 203 ? 0.33360   -25.42747 -42.01863 1.000 44.81000  ? 417 GLU   B N   1 
ATOM   3411 C CA  . GLU   B 1 203 ? 0.07655   -26.80446 -42.42763 1.000 45.60000  ? 417 GLU   B CA  1 
ATOM   3412 C C   . GLU   B 1 203 ? 0.06600   -27.60854 -41.13067 1.000 47.14000  ? 417 GLU   B C   1 
ATOM   3413 O O   . GLU   B 1 203 ? 0.33129   -27.06259 -40.05772 1.000 43.26000  ? 417 GLU   B O   1 
ATOM   3414 C CB  . GLU   B 1 203 ? 1.14630   -27.32535 -43.38098 1.000 41.23000  ? 417 GLU   B CB  1 
ATOM   3415 C CG  . GLU   B 1 203 ? 0.93284   -27.08128 -44.83690 1.000 46.00000  ? 417 GLU   B CG  1 
ATOM   3416 C CD  . GLU   B 1 203 ? 1.88462   -27.90117 -45.70224 1.000 48.34000  ? 417 GLU   B CD  1 
ATOM   3417 O OE1 . GLU   B 1 203 ? 2.08179   -29.09518 -45.39737 1.000 51.39000  ? 417 GLU   B OE1 1 
ATOM   3418 O OE2 . GLU   B 1 203 ? 2.45530   -27.35808 -46.67438 1.000 50.70000  ? 417 GLU   B OE2 1 
ATOM   3419 N N   . VAL   B 1 204 ? -0.23795  -28.90955 -41.20865 1.000 47.14000  ? 418 VAL   B N   1 
ATOM   3420 C CA  . VAL   B 1 204 ? -0.14154  -29.76362 -40.02473 1.000 53.31000  ? 418 VAL   B CA  1 
ATOM   3421 C C   . VAL   B 1 204 ? 1.17850   -30.49254 -40.03218 1.000 47.57000  ? 418 VAL   B C   1 
ATOM   3422 O O   . VAL   B 1 204 ? 1.65521   -30.93145 -41.07635 1.000 55.10000  ? 418 VAL   B O   1 
ATOM   3423 C CB  . VAL   B 1 204 ? -1.29445  -30.77469 -39.89744 1.000 55.68000  ? 418 VAL   B CB  1 
ATOM   3424 C CG1 . VAL   B 1 204 ? -2.54836  -30.07679 -39.48502 1.000 52.03000  ? 418 VAL   B CG1 1 
ATOM   3425 C CG2 . VAL   B 1 204 ? -1.49381  -31.48863 -41.22042 1.000 54.75000  ? 418 VAL   B CG2 1 
ATOM   3426 N N   . SER   B 1 205 ? 1.75786   -30.64057 -38.86136 1.000 53.58000  ? 419 SER   B N   1 
ATOM   3427 C CA  . SER   B 1 205 ? 2.96393   -31.43451 -38.77677 1.000 62.85000  ? 419 SER   B CA  1 
ATOM   3428 C C   . SER   B 1 205 ? 2.61795   -32.89951 -39.01575 1.000 67.80000  ? 419 SER   B C   1 
ATOM   3429 O O   . SER   B 1 205 ? 1.56010   -33.38960 -38.60846 1.000 69.46000  ? 419 SER   B O   1 
ATOM   3430 C CB  . SER   B 1 205 ? 3.63634   -31.24655 -37.41797 1.000 59.58000  ? 419 SER   B CB  1 
ATOM   3431 O OG  . SER   B 1 205 ? 4.99033   -31.63446 -37.50840 1.000 68.82000  ? 419 SER   B OG  1 
ATOM   3432 N N   . THR   B 1 206 ? 3.57982   -33.60943 -39.56409 1.000 69.50000  ? 420 THR   B N   1 
ATOM   3433 C CA  . THR   B 1 206 ? 3.42284   -35.01742 -39.76312 1.000 76.10000  ? 420 THR   B CA  1 
ATOM   3434 C C   . THR   B 1 206 ? 4.47215   -35.66841 -38.88748 1.000 89.57000  ? 420 THR   B C   1 
ATOM   3435 O O   . THR   B 1 206 ? 4.38231   -36.85544 -38.58352 1.000 91.08000  ? 420 THR   B O   1 
ATOM   3436 C CB  . THR   B 1 206 ? 3.71442   -35.36032 -41.21323 1.000 77.06000  ? 420 THR   B CB  1 
ATOM   3437 O OG1 . THR   B 1 206 ? 5.02929   -34.90323 -41.55260 1.000 70.05000  ? 420 THR   B OG1 1 
ATOM   3438 C CG2 . THR   B 1 206 ? 2.71411   -34.67833 -42.11688 1.000 76.25000  ? 420 THR   B CG2 1 
ATOM   3439 N N   . SER   B 1 207 ? 5.48023   -34.90038 -38.48174 1.000 93.40000  ? 421 SER   B N   1 
ATOM   3440 C CA  . SER   B 1 207 ? 6.58850   -35.42536 -37.68210 1.000 94.29000  ? 421 SER   B CA  1 
ATOM   3441 C C   . SER   B 1 207 ? 6.29995   -35.90046 -36.28804 1.000 99.20000  ? 421 SER   B C   1 
ATOM   3442 O O   . SER   B 1 207 ? 5.50313   -35.29554 -35.58577 1.000 100.12000 ? 421 SER   B O   1 
ATOM   3443 C CB  . SER   B 1 207 ? 7.64448   -34.33331 -37.52136 1.000 94.53000  ? 421 SER   B CB  1 
ATOM   3444 O OG  . SER   B 1 207 ? 7.26273   -33.41239 -36.52019 1.000 85.15000  ? 421 SER   B OG  1 
ATOM   3445 N N   . GLU   B 1 208 ? 6.94214   -36.98544 -35.87630 1.000 107.90000 ? 422 GLU   B N   1 
ATOM   3446 C CA  . GLU   B 1 208 ? 6.83958   -37.42953 -34.49730 1.000 108.22000 ? 422 GLU   B CA  1 
ATOM   3447 C C   . GLU   B 1 208 ? 7.43580   -36.38655 -33.58842 1.000 110.97000 ? 422 GLU   B C   1 
ATOM   3448 O O   . GLU   B 1 208 ? 6.88410   -36.09164 -32.52823 1.000 111.66000 ? 422 GLU   B O   1 
ATOM   3449 C CB  . GLU   B 1 208 ? 7.57471   -38.75550 -34.32160 1.000 106.97000 ? 422 GLU   B CB  1 
ATOM   3450 C CG  . GLU   B 1 208 ? 8.36911   -38.87952 -33.02884 1.000 113.81000 ? 422 GLU   B CG  1 
ATOM   3451 C CD  . GLU   B 1 208 ? 7.49449   -38.92565 -31.78858 1.000 115.01000 ? 422 GLU   B CD  1 
ATOM   3452 O OE1 . GLU   B 1 208 ? 6.38651   -39.49471 -31.85128 1.000 114.30000 ? 422 GLU   B OE1 1 
ATOM   3453 O OE2 . GLU   B 1 208 ? 7.92578   -38.39468 -30.74568 1.000 111.37000 ? 422 GLU   B OE2 1 
ATOM   3454 N N   . HIS   B 1 209 ? 8.55164   -35.80346 -34.00672 1.000 109.59000 ? 423 HIS   B N   1 
ATOM   3455 C CA  . HIS   B 1 209 ? 9.26383   -34.81946 -33.19188 1.000 105.36000 ? 423 HIS   B CA  1 
ATOM   3456 C C   . HIS   B 1 209 ? 8.46985   -33.56153 -32.89357 1.000 103.80000 ? 423 HIS   B C   1 
ATOM   3457 O O   . HIS   B 1 209 ? 8.53915   -33.04959 -31.77956 1.000 107.19000 ? 423 HIS   B O   1 
ATOM   3458 C CB  . HIS   B 1 209 ? 10.56659  -34.43935 -33.89326 1.000 107.61000 ? 423 HIS   B CB  1 
ATOM   3459 C CG  . HIS   B 1 209 ? 11.50060  -35.59128 -34.09461 1.000 109.42000 ? 423 HIS   B CG  1 
ATOM   3460 N ND1 . HIS   B 1 209 ? 11.13646  -36.73726 -34.76656 1.000 112.47000 ? 423 HIS   B ND1 1 
ATOM   3461 C CD2 . HIS   B 1 209 ? 12.78772  -35.77123 -33.71701 1.000 107.96000 ? 423 HIS   B CD2 1 
ATOM   3462 C CE1 . HIS   B 1 209 ? 12.15550  -37.57820 -34.78592 1.000 109.08000 ? 423 HIS   B CE1 1 
ATOM   3463 N NE2 . HIS   B 1 209 ? 13.17166  -37.01418 -34.16020 1.000 110.37000 ? 423 HIS   B NE2 1 
ATOM   3464 N N   . GLY   B 1 210 ? 7.72852   -33.04251 -33.86431 1.000 96.31000  ? 424 GLY   B N   1 
ATOM   3465 C CA  . GLY   B 1 210 ? 6.89355   -31.89658 -33.56099 1.000 77.81000  ? 424 GLY   B CA  1 
ATOM   3466 C C   . GLY   B 1 210 ? 6.74017   -30.80853 -34.58388 1.000 73.25000  ? 424 GLY   B C   1 
ATOM   3467 O O   . GLY   B 1 210 ? 7.05983   -30.98044 -35.75199 1.000 70.72000  ? 424 GLY   B O   1 
ATOM   3468 N N   . ALA   B 1 211 ? 6.24224   -29.67658 -34.13967 1.000 62.98000  ? 425 ALA   B N   1 
ATOM   3469 C CA  . ALA   B 1 211 ? 6.04391   -28.54654 -35.02454 1.000 62.24000  ? 425 ALA   B CA  1 
ATOM   3470 C C   . ALA   B 1 211 ? 7.29870   -27.92444 -35.57089 1.000 56.42000  ? 425 ALA   B C   1 
ATOM   3471 O O   . ALA   B 1 211 ? 8.32390   -27.90242 -34.91320 1.000 57.99000  ? 425 ALA   B O   1 
ATOM   3472 C CB  . ALA   B 1 211 ? 5.25607   -27.48163 -34.28924 1.000 59.24000  ? 425 ALA   B CB  1 
ATOM   3473 N N   . GLN   B 1 212 ? 7.22130   -27.42737 -36.79083 1.000 54.54000  ? 426 GLN   B N   1 
ATOM   3474 C CA  . GLN   B 1 212 ? 8.34209   -26.73028 -37.36513 1.000 54.86000  ? 426 GLN   B CA  1 
ATOM   3475 C C   . GLN   B 1 212 ? 7.88782   -25.44327 -37.99292 1.000 49.48000  ? 426 GLN   B C   1 
ATOM   3476 O O   . GLN   B 1 212 ? 6.69576   -25.23433 -38.15655 1.000 45.91000  ? 426 GLN   B O   1 
ATOM   3477 C CB  . GLN   B 1 212 ? 9.00981   -27.58518 -38.43339 1.000 51.76000  ? 426 GLN   B CB  1 
ATOM   3478 C CG  . GLN   B 1 212 ? 9.84504   -28.73816 -37.92271 1.000 58.65000  ? 426 GLN   B CG  1 
ATOM   3479 C CD  . GLN   B 1 212 ? 10.44174  -29.54606 -39.05594 1.000 57.28000  ? 426 GLN   B CD  1 
ATOM   3480 O OE1 . GLN   B 1 212 ? 10.00939  -29.44101 -40.19880 1.000 57.02000  ? 426 GLN   B OE1 1 
ATOM   3481 N NE2 . GLN   B 1 212 ? 11.43588  -30.35902 -38.74228 1.000 66.68000  ? 426 GLN   B NE2 1 
ATOM   3482 N N   . HIS   B 1 213 ? 8.82667   -24.56019 -38.31716 1.000 46.32000  ? 427 HIS   B N   1 
ATOM   3483 C CA  . HIS   B 1 213 ? 8.47638   -23.35417 -39.04998 1.000 46.71000  ? 427 HIS   B CA  1 
ATOM   3484 C C   . HIS   B 1 213 ? 9.58806   -22.97805 -40.03230 1.000 47.40000  ? 427 HIS   B C   1 
ATOM   3485 O O   . HIS   B 1 213 ? 10.76313  -23.32399 -39.85267 1.000 42.78000  ? 427 HIS   B O   1 
ATOM   3486 C CB  . HIS   B 1 213 ? 8.13461   -22.21225 -38.09081 1.000 39.14000  ? 427 HIS   B CB  1 
ATOM   3487 C CG  . HIS   B 1 213 ? 9.24187   -21.84924 -37.16113 1.000 45.42000  ? 427 HIS   B CG  1 
ATOM   3488 N ND1 . HIS   B 1 213 ? 9.88678   -20.63219 -37.21525 1.000 45.18000  ? 427 HIS   B ND1 1 
ATOM   3489 C CD2 . HIS   B 1 213 ? 9.83221   -22.55126 -36.17035 1.000 43.49000  ? 427 HIS   B CD2 1 
ATOM   3490 C CE1 . HIS   B 1 213 ? 10.82306  -20.60019 -36.28653 1.000 47.02000  ? 427 HIS   B CE1 1 
ATOM   3491 N NE2 . HIS   B 1 213 ? 10.81232  -21.75223 -35.64360 1.000 44.90000  ? 427 HIS   B NE2 1 
ATOM   3492 N N   . HIS   B 1 214 ? 9.17469   -22.35201 -41.13114 1.000 44.80000  ? 428 HIS   B N   1 
ATOM   3493 C CA  . HIS   B 1 214 ? 10.07137  -21.70590 -42.07437 1.000 49.67000  ? 428 HIS   B CA  1 
ATOM   3494 C C   . HIS   B 1 214 ? 9.80033   -20.19593 -41.90520 1.000 49.14000  ? 428 HIS   B C   1 
ATOM   3495 O O   . HIS   B 1 214 ? 8.65439   -19.80601 -41.63783 1.000 42.75000  ? 428 HIS   B O   1 
ATOM   3496 C CB  . HIS   B 1 214 ? 9.84096   -22.26083 -43.52833 1.000 40.21000  ? 428 HIS   B CB  1 
ATOM   3497 C CG  . HIS   B 1 214 ? 10.02299  -23.77381 -43.70848 1.000 45.44000  ? 428 HIS   B CG  1 
ATOM   3498 N ND1 . HIS   B 1 214 ? 9.56069   -24.43777 -44.83037 1.000 39.38000  ? 428 HIS   B ND1 1 
ATOM   3499 C CD2 . HIS   B 1 214 ? 10.65927  -24.73082 -42.96472 1.000 51.59000  ? 428 HIS   B CD2 1 
ATOM   3500 C CE1 . HIS   B 1 214 ? 9.84279   -25.73376 -44.73453 1.000 48.69000  ? 428 HIS   B CE1 1 
ATOM   3501 N NE2 . HIS   B 1 214 ? 10.52514  -25.94379 -43.62275 1.000 39.23000  ? 428 HIS   B NE2 1 
ATOM   3502 N N   . VAL   B 1 215 ? 10.84827  -19.34687 -41.93647 1.000 46.22000  ? 429 VAL   B N   1 
ATOM   3503 C CA  . VAL   B 1 215 ? 10.71323  -17.88788 -41.78134 1.000 39.35000  ? 429 VAL   B CA  1 
ATOM   3504 C C   . VAL   B 1 215 ? 11.24681  -17.18578 -43.03547 1.000 44.36000  ? 429 VAL   B C   1 
ATOM   3505 O O   . VAL   B 1 215 ? 12.34168  -17.50069 -43.51482 1.000 44.30000  ? 429 VAL   B O   1 
ATOM   3506 C CB  . VAL   B 1 215 ? 11.43959  -17.36591 -40.51953 1.000 43.05000  ? 429 VAL   B CB  1 
ATOM   3507 C CG1 . VAL   B 1 215 ? 11.67148  -15.84990 -40.56952 1.000 35.85000  ? 429 VAL   B CG1 1 
ATOM   3508 C CG2 . VAL   B 1 215 ? 10.64299  -17.70003 -39.25331 1.000 47.33000  ? 429 VAL   B CG2 1 
ATOM   3509 N N   . TYR   B 1 216 ? 10.48260  -16.21779 -43.55718 1.000 41.70000  ? 430 TYR   B N   1 
ATOM   3510 C CA  . TYR   B 1 216 ? 10.85318  -15.51370 -44.77925 1.000 41.03000  ? 430 TYR   B CA  1 
ATOM   3511 C C   . TYR   B 1 216 ? 10.67214  -14.00672 -44.62011 1.000 43.11000  ? 430 TYR   B C   1 
ATOM   3512 O O   . TYR   B 1 216 ? 9.79134   -13.53181 -43.89081 1.000 42.08000  ? 430 TYR   B O   1 
ATOM   3513 C CB  . TYR   B 1 216 ? 10.01284  -15.95568 -45.99602 1.000 42.41000  ? 430 TYR   B CB  1 
ATOM   3514 C CG  . TYR   B 1 216 ? 9.90185   -17.44367 -46.26007 1.000 41.36000  ? 430 TYR   B CG  1 
ATOM   3515 C CD1 . TYR   B 1 216 ? 8.93409   -18.20776 -45.60582 1.000 45.21000  ? 430 TYR   B CD1 1 
ATOM   3516 C CD2 . TYR   B 1 216 ? 10.72560  -18.08157 -47.18736 1.000 44.59000  ? 430 TYR   B CD2 1 
ATOM   3517 C CE1 . TYR   B 1 216 ? 8.80810   -19.57876 -45.84786 1.000 50.21000  ? 430 TYR   B CE1 1 
ATOM   3518 C CE2 . TYR   B 1 216 ? 10.61060  -19.45656 -47.44540 1.000 49.65000  ? 430 TYR   B CE2 1 
ATOM   3519 C CZ  . TYR   B 1 216 ? 9.64585   -20.19366 -46.77315 1.000 54.94000  ? 430 TYR   B CZ  1 
ATOM   3520 O OH  . TYR   B 1 216 ? 9.51286   -21.54765 -47.00519 1.000 63.09000  ? 430 TYR   B OH  1 
ATOM   3521 N N   . LYS   B 1 217 ? 11.50788  -13.25763 -45.33532 1.000 42.90000  ? 431 LYS   B N   1 
ATOM   3522 C CA  . LYS   B 1 217 ? 11.36677  -11.81463 -45.44519 1.000 43.48000  ? 431 LYS   B CA  1 
ATOM   3523 C C   . LYS   B 1 217 ? 10.42439  -11.50862 -46.60789 1.000 46.51000  ? 431 LYS   B C   1 
ATOM   3524 O O   . LYS   B 1 217 ? 10.59809  -12.05355 -47.69997 1.000 46.43000  ? 431 LYS   B O   1 
ATOM   3525 C CB  . LYS   B 1 217 ? 12.72966  -11.15854 -45.68257 1.000 42.52000  ? 431 LYS   B CB  1 
ATOM   3526 C CG  . LYS   B 1 217 ? 12.70458  -9.63254  -45.63847 1.000 46.87000  ? 431 LYS   B CG  1 
ATOM   3527 C CD  . LYS   B 1 217 ? 11.88592  -9.12466  -44.42119 1.000 54.44000  ? 431 LYS   B CD  1 
ATOM   3528 C CE  . LYS   B 1 217 ? 11.79287  -7.58267  -44.29008 1.000 52.75000  ? 431 LYS   B CE  1 
ATOM   3529 N NZ  . LYS   B 1 217 ? 10.76955  -7.00968  -45.23573 1.000 50.33000  ? 431 LYS   B NZ  1 
ATOM   3530 N N   . LEU   B 1 218 ? 9.43141   -10.64369 -46.38054 1.000 40.51000  ? 432 LEU   B N   1 
ATOM   3531 C CA  . LEU   B 1 218 ? 8.53706   -10.24768 -47.46024 1.000 43.88000  ? 432 LEU   B CA  1 
ATOM   3532 C C   . LEU   B 1 218 ? 9.09576   -9.05860  -48.21934 1.000 47.37000  ? 432 LEU   B C   1 
ATOM   3533 O O   . LEU   B 1 218 ? 9.37888   -8.00962  -47.63337 1.000 48.71000  ? 432 LEU   B O   1 
ATOM   3534 C CB  . LEU   B 1 218 ? 7.14320   -9.89979  -46.93780 1.000 48.74000  ? 432 LEU   B CB  1 
ATOM   3535 C CG  . LEU   B 1 218 ? 6.18033   -11.06086 -46.74857 1.000 45.78000  ? 432 LEU   B CG  1 
ATOM   3536 C CD1 . LEU   B 1 218 ? 4.87150   -10.60997 -46.09215 1.000 43.82000  ? 432 LEU   B CD1 1 
ATOM   3537 C CD2 . LEU   B 1 218 ? 5.93095   -11.69880 -48.10653 1.000 47.74000  ? 432 LEU   B CD2 1 
ATOM   3538 N N   . VAL   B 1 219 ? 9.19137   -9.21352  -49.53738 1.000 49.80000  ? 433 VAL   B N   1 
ATOM   3539 C CA  . VAL   B 1 219 ? 9.78404   -8.23144  -50.43050 1.000 50.97000  ? 433 VAL   B CA  1 
ATOM   3540 C C   . VAL   B 1 219 ? 8.74770   -7.80044  -51.47017 1.000 52.64000  ? 433 VAL   B C   1 
ATOM   3541 O O   . VAL   B 1 219 ? 7.67669   -8.40349  -51.61687 1.000 48.06000  ? 433 VAL   B O   1 
ATOM   3542 C CB  . VAL   B 1 219 ? 11.05887  -8.78432  -51.10292 1.000 51.09000  ? 433 VAL   B CB  1 
ATOM   3543 C CG1 . VAL   B 1 219 ? 12.15819  -8.92332  -50.06527 1.000 45.49000  ? 433 VAL   B CG1 1 
ATOM   3544 C CG2 . VAL   B 1 219 ? 10.80277  -10.14830 -51.70393 1.000 42.63000  ? 433 VAL   B CG2 1 
ATOM   3545 N N   . LYS   B 1 220 ? 9.07742   -6.70338  -52.17820 1.000 58.27000  ? 434 LYS   B N   1 
ATOM   3546 C CA  . LYS   B 1 220 ? 8.29305   -6.18236  -53.31893 1.000 60.65000  ? 434 LYS   B CA  1 
ATOM   3547 C C   . LYS   B 1 220 ? 9.27771   -5.58524  -54.32320 1.000 65.50000  ? 434 LYS   B C   1 
ATOM   3548 O O   . LYS   B 1 220 ? 9.40360   -4.36523  -54.43317 1.000 69.41000  ? 434 LYS   B O   1 
ATOM   3549 C CB  . LYS   B 1 220 ? 7.26211   -5.13744  -52.88956 1.000 58.06000  ? 434 LYS   B CB  1 
ATOM   3550 C CG  . LYS   B 1 220 ? 6.39574   -4.61443  -54.02327 1.000 57.49000  ? 434 LYS   B CG  1 
ATOM   3551 C CD  . LYS   B 1 220 ? 5.78575   -3.22948  -53.71800 1.000 61.21000  ? 434 LYS   B CD  1 
ATOM   3552 C CE  . LYS   B 1 220 ? 4.50201   -3.28960  -52.88561 1.000 61.45000  ? 434 LYS   B CE  1 
ATOM   3553 N NZ  . LYS   B 1 220 ? 3.95403   -1.93165  -52.54437 1.000 58.68000  ? 434 LYS   B NZ  1 
ATOM   3554 N N   . ASP   B 1 221 ? 9.96653   -6.46016  -55.05846 1.000 68.79000  ? 435 ASP   B N   1 
ATOM   3555 C CA  . ASP   B 1 221 ? 11.07824  -6.06504  -55.93777 1.000 75.62000  ? 435 ASP   B CA  1 
ATOM   3556 C C   . ASP   B 1 221 ? 10.86594  -4.74801  -56.67363 1.000 72.50000  ? 435 ASP   B C   1 
ATOM   3557 O O   . ASP   B 1 221 ? 10.94557  -4.71394  -57.89465 1.000 72.52000  ? 435 ASP   B O   1 
ATOM   3558 C CB  . ASP   B 1 221 ? 11.35199  -7.15297  -56.98192 1.000 81.65000  ? 435 ASP   B CB  1 
ATOM   3559 C CG  . ASP   B 1 221 ? 12.18022  -8.30195  -56.43324 1.000 94.53000  ? 435 ASP   B CG  1 
ATOM   3560 O OD1 . ASP   B 1 221 ? 12.64057  -8.21499  -55.26537 1.000 90.74000  ? 435 ASP   B OD1 1 
ATOM   3561 O OD2 . ASP   B 1 221 ? 12.33606  -9.31090  -57.16834 1.000 99.73000  ? 435 ASP   B OD2 1 
ATOM   3562 N N   . SER   C 1 1   ? 8.82310   -28.87626 -44.91813 1.000 51.94000  ? 215 SER   C N   1 
ATOM   3563 C CA  . SER   C 1 1   ? 8.91225   -29.29485 -46.32624 1.000 54.83000  ? 215 SER   C CA  1 
ATOM   3564 C C   . SER   C 1 1   ? 8.06641   -28.49652 -47.33411 1.000 57.08000  ? 215 SER   C C   1 
ATOM   3565 O O   . SER   C 1 1   ? 6.90439   -28.19755 -47.05216 1.000 53.55000  ? 215 SER   C O   1 
ATOM   3566 C CB  . SER   C 1 1   ? 8.52220   -30.75679 -46.46271 1.000 60.17000  ? 215 SER   C CB  1 
ATOM   3567 O OG  . SER   C 1 1   ? 8.82734   -31.21542 -47.77181 1.000 51.58000  ? 215 SER   C OG  1 
ATOM   3568 N N   . GLN   C 1 2   ? 8.63557   -28.18620 -48.51395 1.000 57.79000  ? 216 GLN   C N   1 
ATOM   3569 C CA  . GLN   C 1 2   ? 7.94773   -27.37887 -49.53279 1.000 60.29000  ? 216 GLN   C CA  1 
ATOM   3570 C C   . GLN   C 1 2   ? 8.31688   -27.82647 -50.94988 1.000 57.91000  ? 216 GLN   C C   1 
ATOM   3571 O O   . GLN   C 1 2   ? 9.42195   -27.55438 -51.43267 1.000 55.21000  ? 216 GLN   C O   1 
ATOM   3572 C CB  . GLN   C 1 2   ? 8.23277   -25.87894 -49.32732 1.000 59.82000  ? 216 GLN   C CB  1 
ATOM   3573 C CG  . GLN   C 1 2   ? 9.70679   -25.45700 -49.35302 1.000 57.72000  ? 216 GLN   C CG  1 
ATOM   3574 C CD  . GLN   C 1 2   ? 9.90786   -23.93501 -49.33955 1.000 61.86000  ? 216 GLN   C CD  1 
ATOM   3575 O OE1 . GLN   C 1 2   ? 10.88995  -23.41090 -49.89528 1.000 55.85000  ? 216 GLN   C OE1 1 
ATOM   3576 N NE2 . GLN   C 1 2   ? 8.97482   -23.22216 -48.70645 1.000 65.17000  ? 216 GLN   C NE2 1 
ATOM   3577 N N   . ASP   C 1 3   ? 7.36993   -28.47522 -51.63518 1.000 59.79000  ? 217 ASP   C N   1 
ATOM   3578 C CA  . ASP   C 1 3   ? 7.59206   -29.09385 -52.94834 1.000 58.80000  ? 217 ASP   C CA  1 
ATOM   3579 C C   . ASP   C 1 3   ? 7.06923   -28.18551 -54.04113 1.000 55.19000  ? 217 ASP   C C   1 
ATOM   3580 O O   . ASP   C 1 3   ? 5.87027   -28.19836 -54.34528 1.000 61.19000  ? 217 ASP   C O   1 
ATOM   3581 C CB  . ASP   C 1 3   ? 6.91900   -30.46080 -53.03182 1.000 60.69000  ? 217 ASP   C CB  1 
ATOM   3582 C CG  . ASP   C 1 3   ? 7.38183   -31.38714 -51.91903 1.000 72.39000  ? 217 ASP   C CG  1 
ATOM   3583 O OD1 . ASP   C 1 3   ? 8.31876   -30.97940 -51.18180 1.000 57.32000  ? 217 ASP   C OD1 1 
ATOM   3584 O OD2 . ASP   C 1 3   ? 6.79776   -32.48517 -51.74743 1.000 72.97000  ? 217 ASP   C OD2 1 
ATOM   3585 N N   . ARG   C 1 4   ? 7.97334   -27.42437 -54.64680 1.000 54.95000  ? 218 ARG   C N   1 
ATOM   3586 C CA  . ARG   C 1 4   ? 7.66151   -26.51104 -55.73357 1.000 56.43000  ? 218 ARG   C CA  1 
ATOM   3587 C C   . ARG   C 1 4   ? 8.14464   -27.10667 -57.04869 1.000 59.46000  ? 218 ARG   C C   1 
ATOM   3588 O O   . ARG   C 1 4   ? 9.22162   -27.71771 -57.10674 1.000 55.71000  ? 218 ARG   C O   1 
ATOM   3589 C CB  . ARG   C 1 4   ? 8.32455   -25.14313 -55.51609 1.000 54.95000  ? 218 ARG   C CB  1 
ATOM   3590 C CG  . ARG   C 1 4   ? 7.87843   -24.43048 -54.27194 1.000 55.54000  ? 218 ARG   C CG  1 
ATOM   3591 C CD  . ARG   C 1 4   ? 6.38441   -24.53744 -54.14715 1.000 61.03000  ? 218 ARG   C CD  1 
ATOM   3592 N NE  . ARG   C 1 4   ? 5.73545   -23.24246 -54.00385 1.000 67.70000  ? 218 ARG   C NE  1 
ATOM   3593 C CZ  . ARG   C 1 4   ? 5.12834   -22.82575 -52.90080 1.000 66.68000  ? 218 ARG   C CZ  1 
ATOM   3594 N NH1 . ARG   C 1 4   ? 5.11617   -23.56207 -51.80001 1.000 72.59000  ? 218 ARG   C NH1 1 
ATOM   3595 N NH2 . ARG   C 1 4   ? 4.51439   -21.64572 -52.90453 1.000 59.54000  ? 218 ARG   C NH2 1 
ATOM   3596 N N   . THR   C 1 5   ? 7.33778   -26.93833 -58.09774 1.000 55.81000  ? 219 THR   C N   1 
ATOM   3597 C CA  . THR   C 1 5   ? 7.77192   -27.32196 -59.43080 1.000 50.63000  ? 219 THR   C CA  1 
ATOM   3598 C C   . THR   C 1 5   ? 9.05299   -26.59192 -59.76743 1.000 54.52000  ? 219 THR   C C   1 
ATOM   3599 O O   . THR   C 1 5   ? 9.16202   -25.38499 -59.52706 1.000 50.59000  ? 219 THR   C O   1 
ATOM   3600 C CB  . THR   C 1 5   ? 6.68406   -27.00061 -60.45483 1.000 55.06000  ? 219 THR   C CB  1 
ATOM   3601 O OG1 . THR   C 1 5   ? 5.59299   -27.90162 -60.25623 1.000 58.21000  ? 219 THR   C OG1 1 
ATOM   3602 C CG2 . THR   C 1 5   ? 7.20423   -27.09520 -61.92380 1.000 52.67000  ? 219 THR   C CG2 1 
ATOM   3603 N N   . ILE   C 1 6   ? 10.03602  -27.34382 -60.27653 1.000 50.08000  ? 220 ILE   C N   1 
ATOM   3604 C CA  . ILE   C 1 6   ? 11.27311  -26.79072 -60.81322 1.000 48.56000  ? 220 ILE   C CA  1 
ATOM   3605 C C   . ILE   C 1 6   ? 11.14029  -26.76626 -62.33123 1.000 48.28000  ? 220 ILE   C C   1 
ATOM   3606 O O   . ILE   C 1 6   ? 11.01432  -27.82107 -62.96655 1.000 51.16000  ? 220 ILE   C O   1 
ATOM   3607 C CB  . ILE   C 1 6   ? 12.49902  -27.61290 -60.37331 1.000 55.43000  ? 220 ILE   C CB  1 
ATOM   3608 C CG1 . ILE   C 1 6   ? 12.84785  -27.37235 -58.89020 1.000 50.71000  ? 220 ILE   C CG1 1 
ATOM   3609 C CG2 . ILE   C 1 6   ? 13.72114  -27.37968 -61.31310 1.000 49.44000  ? 220 ILE   C CG2 1 
ATOM   3610 C CD1 . ILE   C 1 6   ? 12.98869  -28.65960 -58.07356 1.000 45.35000  ? 220 ILE   C CD1 1 
ATOM   3611 N N   . ALA   C 1 7   ? 11.17242  -25.57909 -62.92888 1.000 45.16000  ? 221 ALA   C N   1 
ATOM   3612 C CA  . ALA   C 1 7   ? 11.01760  -25.49666 -64.37587 1.000 53.30000  ? 221 ALA   C CA  1 
ATOM   3613 C C   . ALA   C 1 7   ? 11.67472  -24.22853 -64.91042 1.000 49.38000  ? 221 ALA   C C   1 
ATOM   3614 O O   . ALA   C 1 7   ? 11.52170  -23.15270 -64.32613 1.000 48.84000  ? 221 ALA   C O   1 
ATOM   3615 C CB  . ALA   C 1 7   ? 9.52764   -25.53348 -64.76506 1.000 51.28000  ? 221 ALA   C CB  1 
ATOM   3616 N N   . SER   C 1 8   ? 12.40685  -24.36624 -66.02537 1.000 45.99000  ? 222 SER   C N   1 
ATOM   3617 C CA  . SER   C 1 8   ? 12.85099  -23.21203 -66.80598 1.000 45.93000  ? 222 SER   C CA  1 
ATOM   3618 C C   . SER   C 1 8   ? 11.76813  -22.89368 -67.83502 1.000 47.84000  ? 222 SER   C C   1 
ATOM   3619 O O   . SER   C 1 8   ? 10.65910  -23.42965 -67.76631 1.000 46.66000  ? 222 SER   C O   1 
ATOM   3620 C CB  . SER   C 1 8   ? 14.20206  -23.47490 -67.47390 1.000 47.10000  ? 222 SER   C CB  1 
ATOM   3621 O OG  . SER   C 1 8   ? 14.06417  -24.23654 -68.67314 1.000 45.58000  ? 222 SER   C OG  1 
ATOM   3622 N N   . SER   C 1 9   ? 12.05829  -22.03940 -68.82173 1.000 46.07000  ? 223 SER   C N   1 
ATOM   3623 C CA  . SER   C 1 9   ? 11.05642  -21.90905 -69.87782 1.000 45.79000  ? 223 SER   C CA  1 
ATOM   3624 C C   . SER   C 1 9   ? 11.15549  -23.05776 -70.86714 1.000 41.36000  ? 223 SER   C C   1 
ATOM   3625 O O   . SER   C 1 9   ? 10.23457  -23.26649 -71.65131 1.000 44.57000  ? 223 SER   C O   1 
ATOM   3626 C CB  . SER   C 1 9   ? 11.17757  -20.58983 -70.63142 1.000 38.33000  ? 223 SER   C CB  1 
ATOM   3627 O OG  . SER   C 1 9   ? 12.50663  -20.38377 -71.05120 1.000 56.14000  ? 223 SER   C OG  1 
ATOM   3628 N N   . ARG   C 1 10  ? 12.23045  -23.83183 -70.81024 1.000 46.89000  ? 224 ARG   C N   1 
ATOM   3629 C CA  . ARG   C 1 10  ? 12.48452  -24.87856 -71.78252 1.000 48.81000  ? 224 ARG   C CA  1 
ATOM   3630 C C   . ARG   C 1 10  ? 12.38838  -26.28372 -71.21994 1.000 49.42000  ? 224 ARG   C C   1 
ATOM   3631 O O   . ARG   C 1 10  ? 12.21043  -27.22048 -72.00423 1.000 48.73000  ? 224 ARG   C O   1 
ATOM   3632 C CB  . ARG   C 1 10  ? 13.87660  -24.69544 -72.39429 1.000 47.34000  ? 224 ARG   C CB  1 
ATOM   3633 C CG  . ARG   C 1 10  ? 14.04375  -23.44121 -73.21791 1.000 48.70000  ? 224 ARG   C CG  1 
ATOM   3634 C CD  . ARG   C 1 10  ? 14.10892  -23.78877 -74.71100 1.000 64.93000  ? 224 ARG   C CD  1 
ATOM   3635 N NE  . ARG   C 1 10  ? 15.47898  -23.73168 -75.23082 1.000 76.82000  ? 224 ARG   C NE  1 
ATOM   3636 C CZ  . ARG   C 1 10  ? 15.98505  -24.55944 -76.14300 1.000 79.61000  ? 224 ARG   C CZ  1 
ATOM   3637 N NH1 . ARG   C 1 10  ? 15.26107  -25.53825 -76.67638 1.000 75.03000  ? 224 ARG   C NH1 1 
ATOM   3638 N NH2 . ARG   C 1 10  ? 17.24511  -24.39038 -76.55080 1.000 78.81000  ? 224 ARG   C NH2 1 
ATOM   3639 N N   . LEU   C 1 11  ? 12.52122  -26.46411 -69.90298 1.000 47.33000  ? 225 LEU   C N   1 
ATOM   3640 C CA  . LEU   C 1 11  ? 12.60909  -27.80628 -69.34736 1.000 46.71000  ? 225 LEU   C CA  1 
ATOM   3641 C C   . LEU   C 1 11  ? 12.05192  -27.84667 -67.92844 1.000 49.40000  ? 225 LEU   C C   1 
ATOM   3642 O O   . LEU   C 1 11  ? 12.21786  -26.91091 -67.13614 1.000 49.45000  ? 225 LEU   C O   1 
ATOM   3643 C CB  . LEU   C 1 11  ? 14.05107  -28.32034 -69.36234 1.000 46.11000  ? 225 LEU   C CB  1 
ATOM   3644 C CG  . LEU   C 1 11  ? 14.25799  -29.83637 -69.28975 1.000 47.33000  ? 225 LEU   C CG  1 
ATOM   3645 C CD1 . LEU   C 1 11  ? 13.58309  -30.57100 -70.42905 1.000 49.07000  ? 225 LEU   C CD1 1 
ATOM   3646 C CD2 . LEU   C 1 11  ? 15.75597  -30.15145 -69.25767 1.000 49.00000  ? 225 LEU   C CD2 1 
ATOM   3647 N N   . ARG   C 1 12  ? 11.40583  -28.95773 -67.61184 1.000 44.23000  ? 226 ARG   C N   1 
ATOM   3648 C CA  . ARG   C 1 12  ? 10.81366  -29.15809 -66.30597 1.000 51.79000  ? 226 ARG   C CA  1 
ATOM   3649 C C   . ARG   C 1 12  ? 11.40753  -30.41829 -65.70327 1.000 56.87000  ? 226 ARG   C C   1 
ATOM   3650 O O   . ARG   C 1 12  ? 11.65257  -31.39409 -66.41752 1.000 53.09000  ? 226 ARG   C O   1 
ATOM   3651 C CB  . ARG   C 1 12  ? 9.27867   -29.24298 -66.41318 1.000 53.47000  ? 226 ARG   C CB  1 
ATOM   3652 C CG  . ARG   C 1 12  ? 8.55650   -29.75830 -65.20342 1.000 50.98000  ? 226 ARG   C CG  1 
ATOM   3653 C CD  . ARG   C 1 12  ? 7.05153   -29.73017 -65.43559 1.000 59.32000  ? 226 ARG   C CD  1 
ATOM   3654 N NE  . ARG   C 1 12  ? 6.48353   -28.46527 -64.98229 1.000 69.32000  ? 226 ARG   C NE  1 
ATOM   3655 C CZ  . ARG   C 1 12  ? 6.20767   -27.42903 -65.76502 1.000 68.72000  ? 226 ARG   C CZ  1 
ATOM   3656 N NH1 . ARG   C 1 12  ? 6.31483   -27.50365 -67.08303 1.000 57.31000  ? 226 ARG   C NH1 1 
ATOM   3657 N NH2 . ARG   C 1 12  ? 5.81766   -26.28218 -65.20573 1.000 66.89000  ? 226 ARG   C NH2 1 
ATOM   3658 N N   . LEU   C 1 13  ? 11.68737  -30.37069 -64.39422 1.000 57.02000  ? 227 LEU   C N   1 
ATOM   3659 C CA  . LEU   C 1 13  ? 12.17223  -31.52193 -63.64450 1.000 50.78000  ? 227 LEU   C CA  1 
ATOM   3660 C C   . LEU   C 1 13  ? 10.96513  -32.22605 -63.05085 1.000 56.18000  ? 227 LEU   C C   1 
ATOM   3661 O O   . LEU   C 1 13  ? 10.27405  -31.66927 -62.18977 1.000 56.04000  ? 227 LEU   C O   1 
ATOM   3662 C CB  . LEU   C 1 13  ? 13.14212  -31.10629 -62.54426 1.000 48.90000  ? 227 LEU   C CB  1 
ATOM   3663 C CG  . LEU   C 1 13  ? 13.34394  -32.23560 -61.53457 1.000 51.44000  ? 227 LEU   C CG  1 
ATOM   3664 C CD1 . LEU   C 1 13  ? 14.43196  -33.18452 -61.99271 1.000 55.57000  ? 227 LEU   C CD1 1 
ATOM   3665 C CD2 . LEU   C 1 13  ? 13.64880  -31.69302 -60.14337 1.000 52.87000  ? 227 LEU   C CD2 1 
ATOM   3666 N N   . LEU   C 1 14  ? 10.70013  -33.44690 -63.51124 1.000 59.77000  ? 228 LEU   C N   1 
ATOM   3667 C CA  . LEU   C 1 14  ? 9.59702   -34.18802 -62.91959 1.000 59.45000  ? 228 LEU   C CA  1 
ATOM   3668 C C   . LEU   C 1 14  ? 10.05384  -34.99540 -61.70477 1.000 56.80000  ? 228 LEU   C C   1 
ATOM   3669 O O   . LEU   C 1 14  ? 9.32272   -35.09265 -60.72089 1.000 54.78000  ? 228 LEU   C O   1 
ATOM   3670 C CB  . LEU   C 1 14  ? 8.93910   -35.10269 -63.95694 1.000 62.63000  ? 228 LEU   C CB  1 
ATOM   3671 C CG  . LEU   C 1 14  ? 8.72630   -34.65925 -65.40883 1.000 62.64000  ? 228 LEU   C CG  1 
ATOM   3672 C CD1 . LEU   C 1 14  ? 8.62235   -35.87198 -66.33720 1.000 62.91000  ? 228 LEU   C CD1 1 
ATOM   3673 C CD2 . LEU   C 1 14  ? 7.51336   -33.76015 -65.56072 1.000 71.81000  ? 228 LEU   C CD2 1 
ATOM   3674 N N   . GLU   C 1 15  ? 11.25582  -35.57244 -61.74580 1.000 54.46000  ? 229 GLU   C N   1 
ATOM   3675 C CA  . GLU   C 1 15  ? 11.68165  -36.43778 -60.66000 1.000 57.04000  ? 229 GLU   C CA  1 
ATOM   3676 C C   . GLU   C 1 15  ? 13.19763  -36.41890 -60.49181 1.000 60.53000  ? 229 GLU   C C   1 
ATOM   3677 O O   . GLU   C 1 15  ? 13.95675  -36.39265 -61.46971 1.000 55.45000  ? 229 GLU   C O   1 
ATOM   3678 C CB  . GLU   C 1 15  ? 11.22360  -37.88570 -60.86648 1.000 56.97000  ? 229 GLU   C CB  1 
ATOM   3679 C CG  . GLU   C 1 15  ? 12.20748  -38.86594 -60.20565 1.000 65.67000  ? 229 GLU   C CG  1 
ATOM   3680 C CD  . GLU   C 1 15  ? 12.06847  -40.31380 -60.63809 1.000 72.73000  ? 229 GLU   C CD  1 
ATOM   3681 O OE1 . GLU   C 1 15  ? 11.60459  -40.58745 -61.78522 1.000 68.82000  ? 229 GLU   C OE1 1 
ATOM   3682 O OE2 . GLU   C 1 15  ? 12.46033  -41.17106 -59.80929 1.000 69.78000  ? 229 GLU   C OE2 1 
ATOM   3683 N N   . TYR   C 1 16  ? 13.62247  -36.43629 -59.23476 1.000 54.95000  ? 230 TYR   C N   1 
ATOM   3684 C CA  . TYR   C 1 16  ? 14.98642  -36.76246 -58.86470 1.000 53.82000  ? 230 TYR   C CA  1 
ATOM   3685 C C   . TYR   C 1 16  ? 14.92323  -37.70080 -57.67098 1.000 54.13000  ? 230 TYR   C C   1 
ATOM   3686 O O   . TYR   C 1 16  ? 14.28512  -37.37607 -56.66396 1.000 49.84000  ? 230 TYR   C O   1 
ATOM   3687 C CB  . TYR   C 1 16  ? 15.77343  -35.50260 -58.51523 1.000 54.51000  ? 230 TYR   C CB  1 
ATOM   3688 C CG  . TYR   C 1 16  ? 17.27043  -35.68264 -58.58910 1.000 56.15000  ? 230 TYR   C CG  1 
ATOM   3689 C CD1 . TYR   C 1 16  ? 17.87756  -35.98832 -59.79412 1.000 57.41000  ? 230 TYR   C CD1 1 
ATOM   3690 C CD2 . TYR   C 1 16  ? 18.07830  -35.54001 -57.46397 1.000 56.79000  ? 230 TYR   C CD2 1 
ATOM   3691 C CE1 . TYR   C 1 16  ? 19.22057  -36.15035 -59.89101 1.000 60.60000  ? 230 TYR   C CE1 1 
ATOM   3692 C CE2 . TYR   C 1 16  ? 19.46131  -35.69705 -57.55385 1.000 55.46000  ? 230 TYR   C CE2 1 
ATOM   3693 C CZ  . TYR   C 1 16  ? 20.01544  -36.00571 -58.77787 1.000 58.05000  ? 230 TYR   C CZ  1 
ATOM   3694 O OH  . TYR   C 1 16  ? 21.36545  -36.18273 -58.94176 1.000 60.03000  ? 230 TYR   C OH  1 
ATOM   3695 N N   . SER   C 1 17  ? 15.55119  -38.86880 -57.77724 1.000 55.04000  ? 231 SER   C N   1 
ATOM   3696 C CA  . SER   C 1 17  ? 15.60701  -39.78714 -56.64251 1.000 53.20000  ? 231 SER   C CA  1 
ATOM   3697 C C   . SER   C 1 17  ? 17.00897  -40.36423 -56.53051 1.000 56.28000  ? 231 SER   C C   1 
ATOM   3698 O O   . SER   C 1 17  ? 17.64908  -40.67597 -57.54152 1.000 54.26000  ? 231 SER   C O   1 
ATOM   3699 C CB  . SER   C 1 17  ? 14.60297  -40.93605 -56.77696 1.000 52.02000  ? 231 SER   C CB  1 
ATOM   3700 O OG  . SER   C 1 17  ? 13.36505  -40.46485 -57.27098 1.000 59.85000  ? 231 SER   C OG  1 
ATOM   3701 N N   . ALA   C 1 18  ? 17.48482  -40.49162 -55.30049 1.000 51.84000  ? 232 ALA   C N   1 
ATOM   3702 C CA  . ALA   C 1 18  ? 18.69675  -41.23676 -55.00756 1.000 49.39000  ? 232 ALA   C CA  1 
ATOM   3703 C C   . ALA   C 1 18  ? 18.31557  -42.29804 -53.99192 1.000 44.87000  ? 232 ALA   C C   1 
ATOM   3704 O O   . ALA   C 1 18  ? 17.63247  -41.99329 -53.01191 1.000 44.61000  ? 232 ALA   C O   1 
ATOM   3705 C CB  . ALA   C 1 18  ? 19.79672  -40.32397 -54.47016 1.000 45.69000  ? 232 ALA   C CB  1 
ATOM   3706 N N   . PHE   C 1 19  ? 18.73055  -43.53599 -54.22423 1.000 41.50000  ? 233 PHE   C N   1 
ATOM   3707 C CA  . PHE   C 1 19  ? 18.13640  -44.59919 -53.44161 1.000 44.79000  ? 233 PHE   C CA  1 
ATOM   3708 C C   . PHE   C 1 19  ? 19.06134  -45.79624 -53.41485 1.000 44.73000  ? 233 PHE   C C   1 
ATOM   3709 O O   . PHE   C 1 19  ? 19.98344  -45.90905 -54.22277 1.000 48.83000  ? 233 PHE   C O   1 
ATOM   3710 C CB  . PHE   C 1 19  ? 16.77145  -44.98996 -54.01189 1.000 50.12000  ? 233 PHE   C CB  1 
ATOM   3711 C CG  . PHE   C 1 19  ? 16.82061  -45.35554 -55.46299 1.000 47.16000  ? 233 PHE   C CG  1 
ATOM   3712 C CD1 . PHE   C 1 19  ? 16.69577  -44.38725 -56.43372 1.000 46.85000  ? 233 PHE   C CD1 1 
ATOM   3713 C CD2 . PHE   C 1 19  ? 17.04260  -46.66243 -55.85235 1.000 48.27000  ? 233 PHE   C CD2 1 
ATOM   3714 C CE1 . PHE   C 1 19  ? 16.77292  -44.72286 -57.76481 1.000 49.80000  ? 233 PHE   C CE1 1 
ATOM   3715 C CE2 . PHE   C 1 19  ? 17.10474  -47.00205 -57.18144 1.000 52.18000  ? 233 PHE   C CE2 1 
ATOM   3716 C CZ  . PHE   C 1 19  ? 16.97890  -46.03276 -58.14017 1.000 49.61000  ? 233 PHE   C CZ  1 
ATOM   3717 N N   . MET   C 1 20  ? 18.78719  -46.69250 -52.47715 1.000 43.31000  ? 234 MET   C N   1 
ATOM   3718 C CA  . MET   C 1 20  ? 19.36013  -48.02854 -52.45747 1.000 47.70000  ? 234 MET   C CA  1 
ATOM   3719 C C   . MET   C 1 20  ? 18.23808  -49.06249 -52.44291 1.000 55.95000  ? 234 MET   C C   1 
ATOM   3720 O O   . MET   C 1 20  ? 17.24900  -48.91966 -51.70899 1.000 55.09000  ? 234 MET   C O   1 
ATOM   3721 C CB  . MET   C 1 20  ? 20.35198  -48.19193 -51.28440 1.000 54.81000  ? 234 MET   C CB  1 
ATOM   3722 C CG  . MET   C 1 20  ? 19.81281  -48.14032 -49.84845 1.000 54.96000  ? 234 MET   C CG  1 
ATOM   3723 S SD  . MET   C 1 20  ? 20.73963  -49.23568 -48.75766 1.000 69.73000  ? 234 MET   C SD  1 
ATOM   3724 C CE  . MET   C 1 20  ? 20.55566  -50.79643 -49.60114 1.000 71.12000  ? 234 MET   C CE  1 
ATOM   3725 N N   . GLU   C 1 21  ? 18.35614  -50.04824 -53.32818 1.000 57.33000  ? 235 GLU   C N   1 
ATOM   3726 C CA  . GLU   C 1 21  ? 17.42910  -51.16616 -53.44962 1.000 56.38000  ? 235 GLU   C CA  1 
ATOM   3727 C C   . GLU   C 1 21  ? 18.11297  -52.39036 -52.86490 1.000 61.44000  ? 235 GLU   C C   1 
ATOM   3728 O O   . GLU   C 1 21  ? 19.28300  -52.64933 -53.16583 1.000 67.94000  ? 235 GLU   C O   1 
ATOM   3729 C CB  . GLU   C 1 21  ? 17.07927  -51.43271 -54.92074 1.000 60.39000  ? 235 GLU   C CB  1 
ATOM   3730 C CG  . GLU   C 1 21  ? 16.00438  -50.55048 -55.55261 1.000 58.01000  ? 235 GLU   C CG  1 
ATOM   3731 C CD  . GLU   C 1 21  ? 15.93756  -50.71503 -57.07267 1.000 64.93000  ? 235 GLU   C CD  1 
ATOM   3732 O OE1 . GLU   C 1 21  ? 16.82660  -51.39890 -57.64676 1.000 65.33000  ? 235 GLU   C OE1 1 
ATOM   3733 O OE2 . GLU   C 1 21  ? 15.02266  -50.12980 -57.69861 1.000 64.86000  ? 235 GLU   C OE2 1 
ATOM   3734 N N   . VAL   C 1 22  ? 17.40984  -53.12857 -52.02320 1.000 63.37000  ? 236 VAL   C N   1 
ATOM   3735 C CA  . VAL   C 1 22  ? 17.96772  -54.34676 -51.46049 1.000 71.32000  ? 236 VAL   C CA  1 
ATOM   3736 C C   . VAL   C 1 22  ? 16.89268  -55.41069 -51.55193 1.000 73.57000  ? 236 VAL   C C   1 
ATOM   3737 O O   . VAL   C 1 22  ? 15.69569  -55.11465 -51.50099 1.000 74.66000  ? 236 VAL   C O   1 
ATOM   3738 C CB  . VAL   C 1 22  ? 18.48055  -54.14821 -50.00437 1.000 73.54000  ? 236 VAL   C CB  1 
ATOM   3739 C CG1 . VAL   C 1 22  ? 17.46248  -53.42142 -49.15028 1.000 78.54000  ? 236 VAL   C CG1 1 
ATOM   3740 C CG2 . VAL   C 1 22  ? 18.89141  -55.46142 -49.36070 1.000 84.75000  ? 236 VAL   C CG2 1 
ATOM   3741 N N   . GLN   C 1 23  ? 17.31764  -56.64465 -51.74924 1.000 80.79000  ? 237 GLN   C N   1 
ATOM   3742 C CA  . GLN   C 1 23  ? 16.42059  -57.78861 -51.73768 1.000 85.67000  ? 237 GLN   C CA  1 
ATOM   3743 C C   . GLN   C 1 23  ? 16.66840  -58.52401 -50.42587 1.000 91.70000  ? 237 GLN   C C   1 
ATOM   3744 O O   . GLN   C 1 23  ? 17.72735  -59.13211 -50.24392 1.000 95.49000  ? 237 GLN   C O   1 
ATOM   3745 C CB  . GLN   C 1 23  ? 16.67970  -58.68227 -52.94691 1.000 88.01000  ? 237 GLN   C CB  1 
ATOM   3746 C CG  . GLN   C 1 23  ? 16.25661  -60.13530 -52.78739 1.000 98.45000  ? 237 GLN   C CG  1 
ATOM   3747 C CD  . GLN   C 1 23  ? 16.08874  -60.82890 -54.13361 1.000 103.49000 ? 237 GLN   C CD  1 
ATOM   3748 O OE1 . GLN   C 1 23  ? 15.33671  -61.79382 -54.26499 1.000 100.66000 ? 237 GLN   C OE1 1 
ATOM   3749 N NE2 . GLN   C 1 23  ? 16.82088  -60.34963 -55.13839 1.000 101.55000 ? 237 GLN   C NE2 1 
ATOM   3750 N N   . ARG   C 1 24  ? 15.71929  -58.43024 -49.49196 1.000 95.84000  ? 238 ARG   C N   1 
ATOM   3751 C CA  . ARG   C 1 24  ? 15.90410  -59.05463 -48.18012 1.000 104.93000 ? 238 ARG   C CA  1 
ATOM   3752 C C   . ARG   C 1 24  ? 15.93105  -60.57460 -48.29356 1.000 106.28000 ? 238 ARG   C C   1 
ATOM   3753 O O   . ARG   C 1 24  ? 16.95299  -61.21973 -48.02162 1.000 105.50000 ? 238 ARG   C O   1 
ATOM   3754 C CB  . ARG   C 1 24  ? 14.79401  -58.61486 -47.22212 1.000 101.46000 ? 238 ARG   C CB  1 
ATOM   3755 C CG  . ARG   C 1 24  ? 14.46209  -57.15082 -47.31073 1.000 99.22000  ? 238 ARG   C CG  1 
ATOM   3756 C CD  . ARG   C 1 24  ? 15.56906  -56.30704 -46.71835 1.000 102.69000 ? 238 ARG   C CD  1 
ATOM   3757 N NE  . ARG   C 1 24  ? 15.02804  -55.10320 -46.10206 1.000 106.14000 ? 238 ARG   C NE  1 
ATOM   3758 C CZ  . ARG   C 1 24  ? 14.38390  -55.07851 -44.94513 1.000 111.35000 ? 238 ARG   C CZ  1 
ATOM   3759 N NH1 . ARG   C 1 24  ? 14.19776  -56.17871 -44.23248 1.000 116.20000 ? 238 ARG   C NH1 1 
ATOM   3760 N NH2 . ARG   C 1 24  ? 13.91490  -53.91762 -44.49085 1.000 114.07000 ? 238 ARG   C NH2 1 
ATOM   3761 N N   . ASP   C 1 25  ? 14.79507  -61.15744 -48.67487 1.000 106.54000 ? 239 ASP   C N   1 
ATOM   3762 C CA  . ASP   C 1 25  ? 14.55403  -62.56735 -48.93531 1.000 107.76000 ? 239 ASP   C CA  1 
ATOM   3763 C C   . ASP   C 1 25  ? 14.20721  -62.70290 -50.41239 1.000 108.21000 ? 239 ASP   C C   1 
ATOM   3764 O O   . ASP   C 1 25  ? 13.53731  -61.81671 -50.96521 1.000 103.77000 ? 239 ASP   C O   1 
ATOM   3765 C CB  . ASP   C 1 25  ? 13.40490  -63.07556 -48.01859 1.000 103.68000 ? 239 ASP   C CB  1 
ATOM   3766 C CG  . ASP   C 1 25  ? 12.74590  -64.37539 -48.50205 1.000 99.17000  ? 239 ASP   C CG  1 
ATOM   3767 O OD1 . ASP   C 1 25  ? 13.42685  -65.42541 -48.53428 1.000 98.75000  ? 239 ASP   C OD1 1 
ATOM   3768 O OD2 . ASP   C 1 25  ? 11.52293  -64.35825 -48.79220 1.000 87.34000  ? 239 ASP   C OD2 1 
ATOM   3769 N N   . PRO   C 1 26  ? 14.71324  -63.75372 -51.11064 1.000 112.97000 ? 240 PRO   C N   1 
ATOM   3770 C CA  . PRO   C 1 26  ? 14.24339  -64.02429 -52.48077 1.000 110.04000 ? 240 PRO   C CA  1 
ATOM   3771 C C   . PRO   C 1 26  ? 12.73642  -63.83918 -52.62990 1.000 106.58000 ? 240 PRO   C C   1 
ATOM   3772 O O   . PRO   C 1 26  ? 11.95630  -64.46136 -51.89917 1.000 104.42000 ? 240 PRO   C O   1 
ATOM   3773 C CB  . PRO   C 1 26  ? 14.66735  -65.48125 -52.70815 1.000 107.71000 ? 240 PRO   C CB  1 
ATOM   3774 C CG  . PRO   C 1 26  ? 15.94025  -65.60254 -51.91303 1.000 110.08000 ? 240 PRO   C CG  1 
ATOM   3775 C CD  . PRO   C 1 26  ? 15.82215  -64.64988 -50.72377 1.000 107.08000 ? 240 PRO   C CD  1 
ATOM   3776 N N   . ASP   C 1 27  ? 12.33857  -62.95589 -53.55469 1.000 105.99000 ? 241 ASP   C N   1 
ATOM   3777 C CA  . ASP   C 1 27  ? 10.95862  -62.51476 -53.78872 1.000 105.28000 ? 241 ASP   C CA  1 
ATOM   3778 C C   . ASP   C 1 27  ? 10.46354  -61.51304 -52.74149 1.000 102.21000 ? 241 ASP   C C   1 
ATOM   3779 O O   . ASP   C 1 27  ? 9.24453   -61.36104 -52.56759 1.000 99.60000  ? 241 ASP   C O   1 
ATOM   3780 C CB  . ASP   C 1 27  ? 9.97658   -63.69269 -53.89019 1.000 106.10000 ? 241 ASP   C CB  1 
ATOM   3781 C CG  . ASP   C 1 27  ? 10.48863  -64.82545 -54.79046 1.000 108.23000 ? 241 ASP   C CG  1 
ATOM   3782 O OD1 . ASP   C 1 27  ? 10.35579  -64.71708 -56.02944 1.000 112.52000 ? 241 ASP   C OD1 1 
ATOM   3783 O OD2 . ASP   C 1 27  ? 11.00752  -65.83163 -54.25369 1.000 107.46000 ? 241 ASP   C OD2 1 
ATOM   3784 N N   . THR   C 1 28  ? 11.36749  -60.82830 -52.02418 1.000 99.83000  ? 242 THR   C N   1 
ATOM   3785 C CA  . THR   C 1 28  ? 11.02943  -59.69553 -51.15789 1.000 96.29000  ? 242 THR   C CA  1 
ATOM   3786 C C   . THR   C 1 28  ? 12.03451  -58.57452 -51.37644 1.000 90.84000  ? 242 THR   C C   1 
ATOM   3787 O O   . THR   C 1 28  ? 13.24148  -58.77662 -51.20435 1.000 93.96000  ? 242 THR   C O   1 
ATOM   3788 C CB  . THR   C 1 28  ? 11.02424  -60.06397 -49.66700 1.000 95.32000  ? 242 THR   C CB  1 
ATOM   3789 O OG1 . THR   C 1 28  ? 12.34318  -59.88819 -49.12679 1.000 94.47000  ? 242 THR   C OG1 1 
ATOM   3790 C CG2 . THR   C 1 28  ? 10.57215  -61.49201 -49.46247 1.000 92.69000  ? 242 THR   C CG2 1 
ATOM   3791 N N   . TYR   C 1 29  ? 11.53661  -57.38739 -51.71315 1.000 81.41000  ? 243 TYR   C N   1 
ATOM   3792 C CA  . TYR   C 1 29  ? 12.38071  -56.28930 -52.15973 1.000 74.87000  ? 243 TYR   C CA  1 
ATOM   3793 C C   . TYR   C 1 29  ? 11.99468  -55.01149 -51.44640 1.000 62.11000  ? 243 TYR   C C   1 
ATOM   3794 O O   . TYR   C 1 29  ? 10.81068  -54.69848 -51.31145 1.000 75.08000  ? 243 TYR   C O   1 
ATOM   3795 C CB  . TYR   C 1 29  ? 12.23590  -56.06086 -53.65468 1.000 69.34000  ? 243 TYR   C CB  1 
ATOM   3796 C CG  . TYR   C 1 29  ? 12.63995  -57.22463 -54.50197 1.000 76.32000  ? 243 TYR   C CG  1 
ATOM   3797 C CD1 . TYR   C 1 29  ? 13.94400  -57.36056 -54.94386 1.000 81.95000  ? 243 TYR   C CD1 1 
ATOM   3798 C CD2 . TYR   C 1 29  ? 11.69996  -58.16546 -54.91336 1.000 79.98000  ? 243 TYR   C CD2 1 
ATOM   3799 C CE1 . TYR   C 1 29  ? 14.31704  -58.41934 -55.74912 1.000 84.51000  ? 243 TYR   C CE1 1 
ATOM   3800 C CE2 . TYR   C 1 29  ? 12.06600  -59.23225 -55.71463 1.000 83.85000  ? 243 TYR   C CE2 1 
ATOM   3801 C CZ  . TYR   C 1 29  ? 13.37905  -59.35219 -56.13151 1.000 84.41000  ? 243 TYR   C CZ  1 
ATOM   3802 O OH  . TYR   C 1 29  ? 13.76209  -60.40697 -56.92777 1.000 87.02000  ? 243 TYR   C OH  1 
ATOM   3803 N N   . SER   C 1 30  ? 12.98467  -54.25366 -51.03206 1.000 56.90000  ? 244 SER   C N   1 
ATOM   3804 C CA  . SER   C 1 30  ? 12.72865  -52.96483 -50.42071 1.000 59.06000  ? 244 SER   C CA  1 
ATOM   3805 C C   . SER   C 1 30  ? 13.50779  -51.90464 -51.17431 1.000 62.59000  ? 244 SER   C C   1 
ATOM   3806 O O   . SER   C 1 30  ? 14.48987  -52.18548 -51.87527 1.000 59.11000  ? 244 SER   C O   1 
ATOM   3807 C CB  . SER   C 1 30  ? 13.10948  -52.93728 -48.92866 1.000 67.78000  ? 244 SER   C CB  1 
ATOM   3808 O OG  . SER   C 1 30  ? 14.40543  -53.45641 -48.70566 1.000 66.43000  ? 244 SER   C OG  1 
ATOM   3809 N N   . LYS   C 1 31  ? 13.05183  -50.67167 -51.01300 1.000 58.08000  ? 245 LYS   C N   1 
ATOM   3810 C CA  . LYS   C 1 31  ? 13.68196  -49.51252 -51.62359 1.000 57.17000  ? 245 LYS   C CA  1 
ATOM   3811 C C   . LYS   C 1 31  ? 13.76588  -48.41383 -50.57426 1.000 60.61000  ? 245 LYS   C C   1 
ATOM   3812 O O   . LYS   C 1 31  ? 12.73684  -47.99794 -50.03126 1.000 58.60000  ? 245 LYS   C O   1 
ATOM   3813 C CB  . LYS   C 1 31  ? 12.88613  -49.04713 -52.84255 1.000 52.36000  ? 245 LYS   C CB  1 
ATOM   3814 C CG  . LYS   C 1 31  ? 13.59427  -47.97493 -53.63015 1.000 58.56000  ? 245 LYS   C CG  1 
ATOM   3815 C CD  . LYS   C 1 31  ? 12.60639  -47.00871 -54.22198 1.000 64.22000  ? 245 LYS   C CD  1 
ATOM   3816 C CE  . LYS   C 1 31  ? 12.37855  -47.32127 -55.68610 1.000 60.99000  ? 245 LYS   C CE  1 
ATOM   3817 N NZ  . LYS   C 1 31  ? 13.35668  -46.57508 -56.49477 1.000 56.24000  ? 245 LYS   C NZ  1 
ATOM   3818 N N   . HIS   C 1 32  ? 14.97487  -47.94397 -50.27397 1.000 56.71000  ? 246 HIS   C N   1 
ATOM   3819 C CA  . HIS   C 1 32  ? 15.13281  -46.80124 -49.38462 1.000 50.96000  ? 246 HIS   C CA  1 
ATOM   3820 C C   . HIS   C 1 32  ? 15.54897  -45.58502 -50.19921 1.000 52.22000  ? 246 HIS   C C   1 
ATOM   3821 O O   . HIS   C 1 32  ? 16.46806  -45.66482 -51.02613 1.000 48.36000  ? 246 HIS   C O   1 
ATOM   3822 C CB  . HIS   C 1 32  ? 16.14567  -47.06361 -48.27257 1.000 47.12000  ? 246 HIS   C CB  1 
ATOM   3823 C CG  . HIS   C 1 32  ? 16.47063  -45.83186 -47.49717 1.000 49.79000  ? 246 HIS   C CG  1 
ATOM   3824 N ND1 . HIS   C 1 32  ? 15.70652  -45.40813 -46.43514 1.000 52.64000  ? 246 HIS   C ND1 1 
ATOM   3825 C CD2 . HIS   C 1 32  ? 17.44969  -44.90886 -47.65279 1.000 49.33000  ? 246 HIS   C CD2 1 
ATOM   3826 C CE1 . HIS   C 1 32  ? 16.20452  -44.28229 -45.95975 1.000 55.41000  ? 246 HIS   C CE1 1 
ATOM   3827 N NE2 . HIS   C 1 32  ? 17.25762  -43.95513 -46.68553 1.000 57.27000  ? 246 HIS   C NE2 1 
ATOM   3828 N N   . LEU   C 1 33  ? 14.85999  -44.46505 -49.98197 1.000 44.20000  ? 247 LEU   C N   1 
ATOM   3829 C CA  . LEU   C 1 33  ? 15.15114  -43.23386 -50.69757 1.000 43.94000  ? 247 LEU   C CA  1 
ATOM   3830 C C   . LEU   C 1 33  ? 15.96707  -42.33516 -49.78521 1.000 48.89000  ? 247 LEU   C C   1 
ATOM   3831 O O   . LEU   C 1 33  ? 15.54395  -42.02747 -48.66617 1.000 48.71000  ? 247 LEU   C O   1 
ATOM   3832 C CB  . LEU   C 1 33  ? 13.87122  -42.52967 -51.14452 1.000 45.17000  ? 247 LEU   C CB  1 
ATOM   3833 C CG  . LEU   C 1 33  ? 12.85529  -43.31037 -51.99087 1.000 44.08000  ? 247 LEU   C CG  1 
ATOM   3834 C CD1 . LEU   C 1 33  ? 11.59833  -42.52830 -52.05779 1.000 35.90000  ? 247 LEU   C CD1 1 
ATOM   3835 C CD2 . LEU   C 1 33  ? 13.35744  -43.62698 -53.40390 1.000 49.02000  ? 247 LEU   C CD2 1 
ATOM   3836 N N   . PHE   C 1 34  ? 17.15314  -41.94408 -50.25195 1.000 46.71000  ? 248 PHE   C N   1 
ATOM   3837 C CA  . PHE   C 1 34  ? 17.95310  -40.97733 -49.51557 1.000 43.08000  ? 248 PHE   C CA  1 
ATOM   3838 C C   . PHE   C 1 34  ? 17.37818  -39.57526 -49.66423 1.000 41.63000  ? 248 PHE   C C   1 
ATOM   3839 O O   . PHE   C 1 34  ? 17.12609  -38.88754 -48.66706 1.000 44.38000  ? 248 PHE   C O   1 
ATOM   3840 C CB  . PHE   C 1 34  ? 19.40315  -41.04426 -49.99342 1.000 47.68000  ? 248 PHE   C CB  1 
ATOM   3841 C CG  . PHE   C 1 34  ? 20.05906  -42.39835 -49.78774 1.000 51.34000  ? 248 PHE   C CG  1 
ATOM   3842 C CD1 . PHE   C 1 34  ? 20.38189  -42.83974 -48.49283 1.000 49.26000  ? 248 PHE   C CD1 1 
ATOM   3843 C CD2 . PHE   C 1 34  ? 20.38516  -43.21005 -50.87794 1.000 41.96000  ? 248 PHE   C CD2 1 
ATOM   3844 C CE1 . PHE   C 1 34  ? 20.98681  -44.07283 -48.28512 1.000 48.16000  ? 248 PHE   C CE1 1 
ATOM   3845 C CE2 . PHE   C 1 34  ? 21.00308  -44.44213 -50.67522 1.000 47.02000  ? 248 PHE   C CE2 1 
ATOM   3846 C CZ  . PHE   C 1 34  ? 21.30290  -44.87853 -49.36931 1.000 45.80000  ? 248 PHE   C CZ  1 
ATOM   3847 N N   . VAL   C 1 35  ? 17.15935  -39.14189 -50.90313 1.000 37.86000  ? 249 VAL   C N   1 
ATOM   3848 C CA  . VAL   C 1 35  ? 16.53245  -37.86776 -51.23483 1.000 45.13000  ? 249 VAL   C CA  1 
ATOM   3849 C C   . VAL   C 1 35  ? 15.55057  -38.11838 -52.37702 1.000 45.43000  ? 249 VAL   C C   1 
ATOM   3850 O O   . VAL   C 1 35  ? 15.73163  -39.04316 -53.17627 1.000 43.09000  ? 249 VAL   C O   1 
ATOM   3851 C CB  . VAL   C 1 35  ? 17.57355  -36.79769 -51.64239 1.000 46.15000  ? 249 VAL   C CB  1 
ATOM   3852 C CG1 . VAL   C 1 35  ? 18.47642  -36.46207 -50.48019 1.000 43.43000  ? 249 VAL   C CG1 1 
ATOM   3853 C CG2 . VAL   C 1 35  ? 18.39567  -37.27638 -52.84744 1.000 45.55000  ? 249 VAL   C CG2 1 
ATOM   3854 N N   . HIS   C 1 36  ? 14.51562  -37.30031 -52.46391 1.000 49.09000  ? 250 HIS   C N   1 
ATOM   3855 C CA  . HIS   C 1 36  ? 13.57575  -37.44095 -53.56406 1.000 49.59000  ? 250 HIS   C CA  1 
ATOM   3856 C C   . HIS   C 1 36  ? 12.72784  -36.26582 -53.86782 1.000 46.64000  ? 250 HIS   C C   1 
ATOM   3857 O O   . HIS   C 1 36  ? 11.96376  -35.82903 -53.03879 1.000 50.70000  ? 250 HIS   C O   1 
ATOM   3858 C CB  . HIS   C 1 36  ? 12.60466  -38.57698 -53.28551 1.000 51.75000  ? 250 HIS   C CB  1 
ATOM   3859 C CG  . HIS   C 1 36  ? 11.51178  -38.69364 -54.29668 1.000 56.61000  ? 250 HIS   C CG  1 
ATOM   3860 N ND1 . HIS   C 1 36  ? 11.73391  -39.13027 -55.58278 1.000 53.31000  ? 250 HIS   C ND1 1 
ATOM   3861 C CD2 . HIS   C 1 36  ? 10.18678  -38.43560 -54.20976 1.000 52.54000  ? 250 HIS   C CD2 1 
ATOM   3862 C CE1 . HIS   C 1 36  ? 10.59399  -39.13402 -56.24692 1.000 57.37000  ? 250 HIS   C CE1 1 
ATOM   3863 N NE2 . HIS   C 1 36  ? 9.63991   -38.71622 -55.43691 1.000 48.07000  ? 250 HIS   C NE2 1 
ATOM   3864 N N   . ILE   C 1 37  ? 12.87801  -35.71448 -55.05364 1.000 52.48000  ? 251 ILE   C N   1 
ATOM   3865 C CA  . ILE   C 1 37  ? 11.95010  -34.70032 -55.43446 1.000 52.23000  ? 251 ILE   C CA  1 
ATOM   3866 C C   . ILE   C 1 37  ? 11.17220  -35.36298 -56.49874 1.000 55.88000  ? 251 ILE   C C   1 
ATOM   3867 O O   . ILE   C 1 37  ? 11.70930  -35.70370 -57.53678 1.000 53.13000  ? 251 ILE   C O   1 
ATOM   3868 C CB  . ILE   C 1 37  ? 12.63123  -33.51316 -56.09003 1.000 49.01000  ? 251 ILE   C CB  1 
ATOM   3869 C CG1 . ILE   C 1 37  ? 13.42215  -32.71350 -55.06970 1.000 42.79000  ? 251 ILE   C CG1 1 
ATOM   3870 C CG2 . ILE   C 1 37  ? 11.59235  -32.61692 -56.73589 1.000 52.36000  ? 251 ILE   C CG2 1 
ATOM   3871 C CD1 . ILE   C 1 37  ? 14.26227  -31.63535 -55.70228 1.000 47.56000  ? 251 ILE   C CD1 1 
ATOM   3872 N N   . GLY   C 1 38  ? 9.88516   -35.53198 -56.28995 1.000 60.54000  ? 252 GLY   C N   1 
ATOM   3873 C CA  . GLY   C 1 38  ? 9.07125   -36.22566 -57.25325 1.000 64.06000  ? 252 GLY   C CA  1 
ATOM   3874 C C   . GLY   C 1 38  ? 7.62927   -35.81659 -57.26030 1.000 74.67000  ? 252 GLY   C C   1 
ATOM   3875 O O   . GLY   C 1 38  ? 7.02815   -35.66187 -56.21333 1.000 83.02000  ? 252 GLY   C O   1 
ATOM   3876 N N   . GLN   C 1 39  ? 7.06742   -35.63622 -58.44132 1.000 86.39000  ? 253 GLN   C N   1 
ATOM   3877 C CA  . GLN   C 1 39  ? 5.69345   -35.15512 -58.55134 1.000 95.50000  ? 253 GLN   C CA  1 
ATOM   3878 C C   . GLN   C 1 39  ? 4.78951   -36.06884 -59.36172 1.000 92.06000  ? 253 GLN   C C   1 
ATOM   3879 O O   . GLN   C 1 39  ? 5.18461   -36.54455 -60.42581 1.000 82.49000  ? 253 GLN   C O   1 
ATOM   3880 C CB  . GLN   C 1 39  ? 5.68759   -33.74095 -59.13393 1.000 92.47000  ? 253 GLN   C CB  1 
ATOM   3881 C CG  . GLN   C 1 39  ? 6.36676   -33.59359 -60.48780 1.000 96.53000  ? 253 GLN   C CG  1 
ATOM   3882 C CD  . GLN   C 1 39  ? 6.74686   -32.15551 -60.78834 1.000 108.40000 ? 253 GLN   C CD  1 
ATOM   3883 O OE1 . GLN   C 1 39  ? 7.33579   -31.47379 -59.95207 1.000 110.57000 ? 253 GLN   C OE1 1 
ATOM   3884 N NE2 . GLN   C 1 39  ? 6.41902   -31.69015 -61.98824 1.000 106.68000 ? 253 GLN   C NE2 1 
ATOM   3885 N N   . THR   C 1 40  ? 3.59343   -36.33694 -58.84494 1.000 101.93000 ? 254 THR   C N   1 
ATOM   3886 C CA  . THR   C 1 40  ? 2.64347   -37.23369 -59.53132 1.000 98.82000  ? 254 THR   C CA  1 
ATOM   3887 C C   . THR   C 1 40  ? 2.12366   -36.77626 -60.91825 1.000 102.52000 ? 254 THR   C C   1 
ATOM   3888 O O   . THR   C 1 40  ? 1.99273   -37.60099 -61.81750 1.000 104.05000 ? 254 THR   C O   1 
ATOM   3889 C CB  . THR   C 1 40  ? 1.44135   -37.56390 -58.62656 1.000 102.93000 ? 254 THR   C CB  1 
ATOM   3890 O OG1 . THR   C 1 40  ? 1.91018   -37.93831 -57.32461 1.000 100.31000 ? 254 THR   C OG1 1 
ATOM   3891 C CG2 . THR   C 1 40  ? 0.63337   -38.70369 -59.21799 1.000 111.10000 ? 254 THR   C CG2 1 
ATOM   3892 N N   . ASN   C 1 41  ? 1.82474   -35.48920 -61.10191 1.000 111.08000 ? 255 ASN   C N   1 
ATOM   3893 C CA  . ASN   C 1 41  ? 1.26592   -35.03680 -62.37984 1.000 110.22000 ? 255 ASN   C CA  1 
ATOM   3894 C C   . ASN   C 1 41  ? 2.19505   -34.13162 -63.13646 1.000 111.22000 ? 255 ASN   C C   1 
ATOM   3895 O O   . ASN   C 1 41  ? 2.67103   -33.13780 -62.59111 1.000 113.97000 ? 255 ASN   C O   1 
ATOM   3896 C CB  . ASN   C 1 41  ? -0.03207  -34.26880 -62.15977 1.000 102.05000 ? 255 ASN   C CB  1 
ATOM   3897 C CG  . ASN   C 1 41  ? -1.03421  -35.04100 -61.32812 1.000 103.39000 ? 255 ASN   C CG  1 
ATOM   3898 O OD1 . ASN   C 1 41  ? -0.87829  -36.24007 -61.10145 1.000 103.06000 ? 255 ASN   C OD1 1 
ATOM   3899 N ND2 . ASN   C 1 41  ? -2.07423  -34.35409 -60.87004 1.000 104.89000 ? 255 ASN   C ND2 1 
ATOM   3900 N N   . PRO   C 1 42  ? 2.43319   -34.44325 -64.41453 1.000 106.88000 ? 256 PRO   C N   1 
ATOM   3901 C CA  . PRO   C 1 42  ? 3.29133   -33.60405 -65.24918 1.000 103.71000 ? 256 PRO   C CA  1 
ATOM   3902 C C   . PRO   C 1 42  ? 2.63440   -32.27099 -65.34987 1.000 103.42000 ? 256 PRO   C C   1 
ATOM   3903 O O   . PRO   C 1 42  ? 3.29945   -31.25102 -65.34849 1.000 103.17000 ? 256 PRO   C O   1 
ATOM   3904 C CB  . PRO   C 1 42  ? 3.28046   -34.30765 -66.59938 1.000 99.28000  ? 256 PRO   C CB  1 
ATOM   3905 C CG  . PRO   C 1 42  ? 2.08241   -35.19560 -66.57679 1.000 98.43000  ? 256 PRO   C CG  1 
ATOM   3906 C CD  . PRO   C 1 42  ? 1.90122   -35.60102 -65.14693 1.000 107.69000 ? 256 PRO   C CD  1 
ATOM   3907 N N   . ALA   C 1 43  ? 1.32542   -32.27289 -65.47302 1.000 97.91000  ? 257 ALA   C N   1 
ATOM   3908 C CA  . ALA   C 1 43  ? 0.58948   -31.03084 -65.52275 1.000 102.97000 ? 257 ALA   C CA  1 
ATOM   3909 C C   . ALA   C 1 43  ? 0.70636   -30.20422 -64.25149 1.000 106.03000 ? 257 ALA   C C   1 
ATOM   3910 O O   . ALA   C 1 43  ? 0.80943   -28.98220 -64.33012 1.000 103.56000 ? 257 ALA   C O   1 
ATOM   3911 C CB  . ALA   C 1 43  ? -0.86850  -31.31569 -65.80801 1.000 104.33000 ? 257 ALA   C CB  1 
ATOM   3912 N N   . PHE   C 1 44  ? 0.67020   -30.83556 -63.08368 1.000 102.94000 ? 258 PHE   C N   1 
ATOM   3913 C CA  . PHE   C 1 44  ? 0.66608   -30.04992 -61.84945 1.000 101.65000 ? 258 PHE   C CA  1 
ATOM   3914 C C   . PHE   C 1 44  ? 1.68414   -28.89896 -61.87099 1.000 97.32000  ? 258 PHE   C C   1 
ATOM   3915 O O   . PHE   C 1 44  ? 2.80619   -29.07188 -62.33391 1.000 91.67000  ? 258 PHE   C O   1 
ATOM   3916 C CB  . PHE   C 1 44  ? 0.89090   -30.94229 -60.63869 1.000 99.54000  ? 258 PHE   C CB  1 
ATOM   3917 C CG  . PHE   C 1 44  ? 1.02878   -30.18167 -59.35845 1.000 110.02000 ? 258 PHE   C CG  1 
ATOM   3918 C CD1 . PHE   C 1 44  ? -0.05826  -29.53178 -58.80739 1.000 113.94000 ? 258 PHE   C CD1 1 
ATOM   3919 C CD2 . PHE   C 1 44  ? 2.24870   -30.10192 -58.71228 1.000 109.70000 ? 258 PHE   C CD2 1 
ATOM   3920 C CE1 . PHE   C 1 44  ? 0.06263   -28.82113 -57.63116 1.000 108.70000 ? 258 PHE   C CE1 1 
ATOM   3921 C CE2 . PHE   C 1 44  ? 2.37759   -29.39327 -57.53505 1.000 106.00000 ? 258 PHE   C CE2 1 
ATOM   3922 C CZ  . PHE   C 1 44  ? 1.28256   -28.75238 -56.99300 1.000 104.10000 ? 258 PHE   C CZ  1 
ATOM   3923 N N   . SER   C 1 45  ? 1.28613   -27.72209 -61.38669 1.000 90.79000  ? 259 SER   C N   1 
ATOM   3924 C CA  . SER   C 1 45  ? 2.22018   -26.60014 -61.34625 1.000 80.19000  ? 259 SER   C CA  1 
ATOM   3925 C C   . SER   C 1 45  ? 2.23006   -25.87553 -60.02604 1.000 71.31000  ? 259 SER   C C   1 
ATOM   3926 O O   . SER   C 1 45  ? 1.18600   -25.56564 -59.48007 1.000 75.31000  ? 259 SER   C O   1 
ATOM   3927 C CB  . SER   C 1 45  ? 1.89836   -25.59581 -62.44000 1.000 80.82000  ? 259 SER   C CB  1 
ATOM   3928 O OG  . SER   C 1 45  ? 2.81941   -24.52085 -62.42757 1.000 78.39000  ? 259 SER   C OG  1 
ATOM   3929 N N   . ASP   C 1 46  ? 3.41201   -25.57573 -59.53081 1.000 65.60000  ? 260 ASP   C N   1 
ATOM   3930 C CA  . ASP   C 1 46  ? 3.57589   -24.91412 -58.23760 1.000 64.65000  ? 260 ASP   C CA  1 
ATOM   3931 C C   . ASP   C 1 46  ? 4.95691   -24.27019 -58.21624 1.000 62.43000  ? 260 ASP   C C   1 
ATOM   3932 O O   . ASP   C 1 46  ? 5.82380   -24.62846 -57.40424 1.000 57.63000  ? 260 ASP   C O   1 
ATOM   3933 C CB  . ASP   C 1 46  ? 3.39270   -25.91444 -57.09191 1.000 61.75000  ? 260 ASP   C CB  1 
ATOM   3934 C CG  . ASP   C 1 46  ? 3.17857   -25.23883 -55.75374 1.000 68.33000  ? 260 ASP   C CG  1 
ATOM   3935 O OD1 . ASP   C 1 46  ? 2.99463   -23.99583 -55.72240 1.000 67.50000  ? 260 ASP   C OD1 1 
ATOM   3936 O OD2 . ASP   C 1 46  ? 3.23841   -25.96113 -54.72494 1.000 65.55000  ? 260 ASP   C OD2 1 
ATOM   3937 N N   . PRO   C 1 47  ? 5.19406   -23.30194 -59.10393 1.000 56.26000  ? 261 PRO   C N   1 
ATOM   3938 C CA  . PRO   C 1 47  ? 6.50710   -22.66098 -59.17058 1.000 52.52000  ? 261 PRO   C CA  1 
ATOM   3939 C C   . PRO   C 1 47  ? 6.82997   -21.99538 -57.84235 1.000 59.91000  ? 261 PRO   C C   1 
ATOM   3940 O O   . PRO   C 1 47  ? 5.92191   -21.53655 -57.12832 1.000 57.78000  ? 261 PRO   C O   1 
ATOM   3941 C CB  . PRO   C 1 47  ? 6.33928   -21.62464 -60.28730 1.000 45.51000  ? 261 PRO   C CB  1 
ATOM   3942 C CG  . PRO   C 1 47  ? 4.91229   -21.28959 -60.24237 1.000 51.41000  ? 261 PRO   C CG  1 
ATOM   3943 C CD  . PRO   C 1 47  ? 4.19619   -22.56866 -59.89483 1.000 55.93000  ? 261 PRO   C CD  1 
ATOM   3944 N N   . PRO   C 1 48  ? 8.10393   -21.94555 -57.46118 1.000 54.45000  ? 262 PRO   C N   1 
ATOM   3945 C CA  . PRO   C 1 48  ? 8.45179   -21.47096 -56.11500 1.000 55.02000  ? 262 PRO   C CA  1 
ATOM   3946 C C   . PRO   C 1 48  ? 8.24984   -19.96901 -55.92859 1.000 49.86000  ? 262 PRO   C C   1 
ATOM   3947 O O   . PRO   C 1 48  ? 8.69897   -19.15179 -56.73529 1.000 52.92000  ? 262 PRO   C O   1 
ATOM   3948 C CB  . PRO   C 1 48  ? 9.92475   -21.87507 -55.96494 1.000 52.85000  ? 262 PRO   C CB  1 
ATOM   3949 C CG  . PRO   C 1 48  ? 10.38990  -22.18569 -57.35298 1.000 49.80000  ? 262 PRO   C CG  1 
ATOM   3950 C CD  . PRO   C 1 48  ? 9.20597   -22.69742 -58.07827 1.000 49.77000  ? 262 PRO   C CD  1 
ATOM   3951 N N   . LEU   C 1 49  ? 7.56372   -19.62030 -54.83557 1.000 49.72000  ? 263 LEU   C N   1 
ATOM   3952 C CA  . LEU   C 1 49  ? 7.43872   -18.25143 -54.34418 1.000 51.36000  ? 263 LEU   C CA  1 
ATOM   3953 C C   . LEU   C 1 49  ? 8.64665   -17.82173 -53.53191 1.000 51.32000  ? 263 LEU   C C   1 
ATOM   3954 O O   . LEU   C 1 49  ? 8.83167   -16.62281 -53.29354 1.000 51.90000  ? 263 LEU   C O   1 
ATOM   3955 C CB  . LEU   C 1 49  ? 6.19862   -18.12364 -53.45529 1.000 51.90000  ? 263 LEU   C CB  1 
ATOM   3956 C CG  . LEU   C 1 49  ? 4.89672   -17.77437 -54.14935 1.000 51.05000  ? 263 LEU   C CG  1 
ATOM   3957 C CD1 . LEU   C 1 49  ? 4.45175   -19.03515 -54.85977 1.000 51.37000  ? 263 LEU   C CD1 1 
ATOM   3958 C CD2 . LEU   C 1 49  ? 3.85762   -17.34263 -53.12634 1.000 51.11000  ? 263 LEU   C CD2 1 
ATOM   3959 N N   . GLU   C 1 50  ? 9.45755   -18.78688 -53.12209 1.000 49.22000  ? 264 GLU   C N   1 
ATOM   3960 C CA  . GLU   C 1 50  ? 10.54045  -18.63321 -52.17292 1.000 46.15000  ? 264 GLU   C CA  1 
ATOM   3961 C C   . GLU   C 1 50  ? 11.84755  -18.41305 -52.93670 1.000 47.25000  ? 264 GLU   C C   1 
ATOM   3962 O O   . GLU   C 1 50  ? 12.25360  -19.27584 -53.72190 1.000 49.80000  ? 264 GLU   C O   1 
ATOM   3963 C CB  . GLU   C 1 50  ? 10.60928  -19.90347 -51.31228 1.000 50.39000  ? 264 GLU   C CB  1 
ATOM   3964 C CG  . GLU   C 1 50  ? 9.28718   -20.33860 -50.65457 1.000 50.16000  ? 264 GLU   C CG  1 
ATOM   3965 C CD  . GLU   C 1 50  ? 8.26627   -21.04627 -51.60490 1.000 59.39000  ? 264 GLU   C CD  1 
ATOM   3966 O OE1 . GLU   C 1 50  ? 8.51341   -21.16393 -52.83190 1.000 58.49000  ? 264 GLU   C OE1 1 
ATOM   3967 O OE2 . GLU   C 1 50  ? 7.19319   -21.48637 -51.11916 1.000 57.38000  ? 264 GLU   C OE2 1 
ATOM   3968 N N   . ALA   C 1 51  ? 12.50457  -17.26915 -52.70228 1.000 42.06000  ? 265 ALA   C N   1 
ATOM   3969 C CA  . ALA   C 1 51  ? 13.72667  -16.88300 -53.40502 1.000 45.18000  ? 265 ALA   C CA  1 
ATOM   3970 C C   . ALA   C 1 51  ? 14.95156  -16.87832 -52.48187 1.000 48.16000  ? 265 ALA   C C   1 
ATOM   3971 O O   . ALA   C 1 51  ? 14.84543  -16.57767 -51.29480 1.000 51.13000  ? 265 ALA   C O   1 
ATOM   3972 C CB  . ALA   C 1 51  ? 13.57181  -15.49281 -54.03063 1.000 42.93000  ? 265 ALA   C CB  1 
ATOM   3973 N N   . VAL   C 1 52  ? 16.12062  -17.18522 -53.03982 1.000 47.79000  ? 266 VAL   C N   1 
ATOM   3974 C CA  . VAL   C 1 52  ? 17.41354  -17.08747 -52.36664 1.000 42.76000  ? 266 VAL   C CA  1 
ATOM   3975 C C   . VAL   C 1 52  ? 18.37969  -16.36524 -53.30331 1.000 48.65000  ? 266 VAL   C C   1 
ATOM   3976 O O   . VAL   C 1 52  ? 18.32382  -16.54388 -54.52837 1.000 49.72000  ? 266 VAL   C O   1 
ATOM   3977 C CB  . VAL   C 1 52  ? 17.97543  -18.48161 -51.99898 1.000 43.60000  ? 266 VAL   C CB  1 
ATOM   3978 C CG1 . VAL   C 1 52  ? 19.44738  -18.41281 -51.52778 1.000 37.21000  ? 266 VAL   C CG1 1 
ATOM   3979 C CG2 . VAL   C 1 52  ? 17.07928  -19.18386 -50.99829 1.000 44.75000  ? 266 VAL   C CG2 1 
ATOM   3980 N N   . ASP   C 1 53  ? 19.27265  -15.55545 -52.73697 1.000 51.52000  ? 267 ASP   C N   1 
ATOM   3981 C CA  . ASP   C 1 53  ? 20.25378  -14.85826 -53.55264 1.000 47.60000  ? 267 ASP   C CA  1 
ATOM   3982 C C   . ASP   C 1 53  ? 21.42478  -15.77822 -53.86677 1.000 51.41000  ? 267 ASP   C C   1 
ATOM   3983 O O   . ASP   C 1 53  ? 22.06265  -16.32551 -52.95786 1.000 51.57000  ? 267 ASP   C O   1 
ATOM   3984 C CB  . ASP   C 1 53  ? 20.73976  -13.58548 -52.86321 1.000 45.51000  ? 267 ASP   C CB  1 
ATOM   3985 C CG  . ASP   C 1 53  ? 21.51292  -12.68024 -53.81686 1.000 54.92000  ? 267 ASP   C CG  1 
ATOM   3986 O OD1 . ASP   C 1 53  ? 22.31299  -13.21804 -54.59392 1.000 57.71000  ? 267 ASP   C OD1 1 
ATOM   3987 O OD2 . ASP   C 1 53  ? 21.31698  -11.44922 -53.83052 1.000 58.94000  ? 267 ASP   C OD2 1 
ATOM   3988 N N   . VAL   C 1 54  ? 21.71193  -15.92985 -55.16378 1.000 47.97000  ? 268 VAL   C N   1 
ATOM   3989 C CA  . VAL   C 1 54  ? 22.73794  -16.87677 -55.59694 1.000 50.57000  ? 268 VAL   C CA  1 
ATOM   3990 C C   . VAL   C 1 54  ? 24.05586  -16.63804 -54.87771 1.000 53.63000  ? 268 VAL   C C   1 
ATOM   3991 O O   . VAL   C 1 54  ? 24.78178  -17.59217 -54.56890 1.000 56.16000  ? 268 VAL   C O   1 
ATOM   3992 C CB  . VAL   C 1 54  ? 22.90712  -16.82533 -57.13390 1.000 50.53000  ? 268 VAL   C CB  1 
ATOM   3993 C CG1 . VAL   C 1 54  ? 23.55824  -15.52923 -57.57744 1.000 50.96000  ? 268 VAL   C CG1 1 
ATOM   3994 C CG2 . VAL   C 1 54  ? 23.71113  -18.01023 -57.60915 1.000 49.83000  ? 268 VAL   C CG2 1 
ATOM   3995 N N   . ARG   C 1 55  ? 24.36888  -15.37915 -54.55030 1.000 52.78000  ? 269 ARG   C N   1 
ATOM   3996 C CA  . ARG   C 1 55  ? 25.64082  -15.07740 -53.90006 1.000 53.96000  ? 269 ARG   C CA  1 
ATOM   3997 C C   . ARG   C 1 55  ? 25.73862  -15.73981 -52.53124 1.000 58.19000  ? 269 ARG   C C   1 
ATOM   3998 O O   . ARG   C 1 55  ? 26.84555  -16.06999 -52.07921 1.000 59.41000  ? 269 ARG   C O   1 
ATOM   3999 C CB  . ARG   C 1 55  ? 25.80787  -13.56945 -53.75360 1.000 53.05000  ? 269 ARG   C CB  1 
ATOM   4000 C CG  . ARG   C 1 55  ? 25.14104  -12.77210 -54.85445 1.000 53.12000  ? 269 ARG   C CG  1 
ATOM   4001 C CD  . ARG   C 1 55  ? 25.64111  -11.34810 -54.91697 1.000 57.06000  ? 269 ARG   C CD  1 
ATOM   4002 N NE  . ARG   C 1 55  ? 24.80425  -10.51581 -55.77083 1.000 58.74000  ? 269 ARG   C NE  1 
ATOM   4003 C CZ  . ARG   C 1 55  ? 23.88624  -9.67090  -55.32469 1.000 64.19000  ? 269 ARG   C CZ  1 
ATOM   4004 N NH1 . ARG   C 1 55  ? 23.68009  -9.49927  -54.03066 1.000 66.76000  ? 269 ARG   C NH1 1 
ATOM   4005 N NH2 . ARG   C 1 55  ? 23.15937  -8.97461  -56.19857 1.000 67.10000  ? 269 ARG   C NH2 1 
ATOM   4006 N N   . GLN   C 1 56  ? 24.59853  -15.93095 -51.84744 1.000 53.42000  ? 270 GLN   C N   1 
ATOM   4007 C CA  . GLN   C 1 56  ? 24.62834  -16.55434 -50.52762 1.000 50.88000  ? 270 GLN   C CA  1 
ATOM   4008 C C   . GLN   C 1 56  ? 25.10328  -17.99535 -50.57798 1.000 50.84000  ? 270 GLN   C C   1 
ATOM   4009 O O   . GLN   C 1 56  ? 25.49613  -18.54067 -49.54009 1.000 57.31000  ? 270 GLN   C O   1 
ATOM   4010 C CB  . GLN   C 1 56  ? 23.24526  -16.50448 -49.85577 1.000 52.82000  ? 270 GLN   C CB  1 
ATOM   4011 C CG  . GLN   C 1 56  ? 22.73929  -15.12654 -49.54242 1.000 48.11000  ? 270 GLN   C CG  1 
ATOM   4012 C CD  . GLN   C 1 56  ? 23.71522  -14.36984 -48.68209 1.000 60.67000  ? 270 GLN   C CD  1 
ATOM   4013 O OE1 . GLN   C 1 56  ? 24.46510  -14.96411 -47.89017 1.000 62.93000  ? 270 GLN   C OE1 1 
ATOM   4014 N NE2 . GLN   C 1 56  ? 23.71530  -13.05080 -48.81170 1.000 64.31000  ? 270 GLN   C NE2 1 
ATOM   4015 N N   . ILE   C 1 57  ? 25.07739  -18.62601 -51.74517 1.000 48.06000  ? 271 ILE   C N   1 
ATOM   4016 C CA  . ILE   C 1 57  ? 25.54435  -19.99399 -51.88351 1.000 49.53000  ? 271 ILE   C CA  1 
ATOM   4017 C C   . ILE   C 1 57  ? 26.74046  -20.08877 -52.81840 1.000 49.83000  ? 271 ILE   C C   1 
ATOM   4018 O O   . ILE   C 1 57  ? 27.12345  -21.19267 -53.22267 1.000 50.12000  ? 271 ILE   C O   1 
ATOM   4019 C CB  . ILE   C 1 57  ? 24.40436  -20.93981 -52.31193 1.000 49.28000  ? 271 ILE   C CB  1 
ATOM   4020 C CG1 . ILE   C 1 57  ? 23.79154  -20.55638 -53.66589 1.000 45.84000  ? 271 ILE   C CG1 1 
ATOM   4021 C CG2 . ILE   C 1 57  ? 23.32023  -20.90806 -51.27405 1.000 47.62000  ? 271 ILE   C CG2 1 
ATOM   4022 C CD1 . ILE   C 1 57  ? 23.59859  -21.72711 -54.59026 1.000 42.55000  ? 271 ILE   C CD1 1 
ATOM   4023 N N   . TYR   C 1 58  ? 27.37255  -18.94970 -53.13499 1.000 53.99000  ? 272 TYR   C N   1 
ATOM   4024 C CA  . TYR   C 1 58  ? 28.58265  -18.95852 -53.95884 1.000 62.54000  ? 272 TYR   C CA  1 
ATOM   4025 C C   . TYR   C 1 58  ? 29.70453  -19.74777 -53.28994 1.000 54.85000  ? 272 TYR   C C   1 
ATOM   4026 O O   . TYR   C 1 58  ? 30.37957  -20.54961 -53.94109 1.000 53.06000  ? 272 TYR   C O   1 
ATOM   4027 C CB  . TYR   C 1 58  ? 29.06274  -17.52746 -54.23637 1.000 59.31000  ? 272 TYR   C CB  1 
ATOM   4028 C CG  . TYR   C 1 58  ? 28.43292  -16.80908 -55.41723 1.000 53.31000  ? 272 TYR   C CG  1 
ATOM   4029 C CD1 . TYR   C 1 58  ? 27.59000  -17.47079 -56.30653 1.000 58.76000  ? 272 TYR   C CD1 1 
ATOM   4030 C CD2 . TYR   C 1 58  ? 28.70901  -15.45803 -55.65180 1.000 46.47000  ? 272 TYR   C CD2 1 
ATOM   4031 C CE1 . TYR   C 1 58  ? 27.01116  -16.79044 -57.39040 1.000 54.58000  ? 272 TYR   C CE1 1 
ATOM   4032 C CE2 . TYR   C 1 58  ? 28.15017  -14.77769 -56.70967 1.000 48.96000  ? 272 TYR   C CE2 1 
ATOM   4033 C CZ  . TYR   C 1 58  ? 27.30224  -15.44740 -57.58197 1.000 54.17000  ? 272 TYR   C CZ  1 
ATOM   4034 O OH  . TYR   C 1 58  ? 26.75640  -14.76006 -58.64483 1.000 62.98000  ? 272 TYR   C OH  1 
ATOM   4035 N N   . ASP   C 1 59  ? 29.90938  -19.55116 -51.98386 1.000 53.48000  ? 273 ASP   C N   1 
ATOM   4036 C CA  . ASP   C 1 59  ? 31.01127  -20.25340 -51.33493 1.000 54.78000  ? 273 ASP   C CA  1 
ATOM   4037 C C   . ASP   C 1 59  ? 30.78420  -21.76440 -51.30640 1.000 58.64000  ? 273 ASP   C C   1 
ATOM   4038 O O   . ASP   C 1 59  ? 31.75916  -22.52645 -51.27451 1.000 55.32000  ? 273 ASP   C O   1 
ATOM   4039 C CB  . ASP   C 1 59  ? 31.23912  -19.71883 -49.91575 1.000 51.35000  ? 273 ASP   C CB  1 
ATOM   4040 C CG  . ASP   C 1 59  ? 31.58119  -18.22185 -49.88127 1.000 59.20000  ? 273 ASP   C CG  1 
ATOM   4041 O OD1 . ASP   C 1 59  ? 31.97334  -17.66756 -50.93406 1.000 57.54000  ? 273 ASP   C OD1 1 
ATOM   4042 O OD2 . ASP   C 1 59  ? 31.46909  -17.60417 -48.78710 1.000 59.69000  ? 273 ASP   C OD2 1 
ATOM   4043 N N   . LYS   C 1 60  ? 29.51518  -22.21834 -51.31969 1.000 58.71000  ? 274 LYS   C N   1 
ATOM   4044 C CA  . LYS   C 1 60  ? 29.20409  -23.64037 -51.15514 1.000 56.06000  ? 274 LYS   C CA  1 
ATOM   4045 C C   . LYS   C 1 60  ? 29.46521  -24.44601 -52.41635 1.000 54.76000  ? 274 LYS   C C   1 
ATOM   4046 O O   . LYS   C 1 60  ? 29.46715  -25.68302 -52.37371 1.000 56.55000  ? 274 LYS   C O   1 
ATOM   4047 C CB  . LYS   C 1 60  ? 27.74503  -23.82543 -50.71437 1.000 54.59000  ? 274 LYS   C CB  1 
ATOM   4048 C CG  . LYS   C 1 60  ? 27.42190  -23.14280 -49.40221 1.000 55.57000  ? 274 LYS   C CG  1 
ATOM   4049 C CD  . LYS   C 1 60  ? 26.74074  -24.08606 -48.42157 1.000 63.36000  ? 274 LYS   C CD  1 
ATOM   4050 C CE  . LYS   C 1 60  ? 26.27163  -23.30839 -47.20740 1.000 66.33000  ? 274 LYS   C CE  1 
ATOM   4051 N NZ  . LYS   C 1 60  ? 25.73075  -21.97424 -47.64107 1.000 68.99000  ? 274 LYS   C NZ  1 
ATOM   4052 N N   . PHE   C 1 61  ? 29.68937  -23.77370 -53.52512 1.000 57.20000  ? 275 PHE   C N   1 
ATOM   4053 C CA  . PHE   C 1 61  ? 29.96149  -24.41834 -54.77728 1.000 58.90000  ? 275 PHE   C CA  1 
ATOM   4054 C C   . PHE   C 1 61  ? 31.26359  -23.84824 -55.33596 1.000 68.28000  ? 275 PHE   C C   1 
ATOM   4055 O O   . PHE   C 1 61  ? 31.53662  -22.65730 -55.16357 1.000 66.28000  ? 275 PHE   C O   1 
ATOM   4056 C CB  . PHE   C 1 61  ? 28.76462  -24.21400 -55.75936 1.000 57.32000  ? 275 PHE   C CB  1 
ATOM   4057 C CG  . PHE   C 1 61  ? 27.51054  -24.98806 -55.37374 1.000 52.18000  ? 275 PHE   C CG  1 
ATOM   4058 C CD1 . PHE   C 1 61  ? 26.63845  -24.49429 -54.42570 1.000 46.92000  ? 275 PHE   C CD1 1 
ATOM   4059 C CD2 . PHE   C 1 61  ? 27.22555  -26.22788 -55.93914 1.000 51.79000  ? 275 PHE   C CD2 1 
ATOM   4060 C CE1 . PHE   C 1 61  ? 25.50937  -25.21635 -54.06005 1.000 45.94000  ? 275 PHE   C CE1 1 
ATOM   4061 C CE2 . PHE   C 1 61  ? 26.09747  -26.94994 -55.56348 1.000 45.76000  ? 275 PHE   C CE2 1 
ATOM   4062 C CZ  . PHE   C 1 61  ? 25.24938  -26.44817 -54.62644 1.000 42.05000  ? 275 PHE   C CZ  1 
ATOM   4063 N N   . PRO   C 1 62  ? 32.10162  -24.66909 -55.97109 1.000 78.00000  ? 276 PRO   C N   1 
ATOM   4064 C CA  . PRO   C 1 62  ? 33.46969  -24.23605 -56.31280 1.000 82.72000  ? 276 PRO   C CA  1 
ATOM   4065 C C   . PRO   C 1 62  ? 33.46387  -23.17873 -57.41249 1.000 81.34000  ? 276 PRO   C C   1 
ATOM   4066 O O   . PRO   C 1 62  ? 33.16799  -23.46538 -58.57561 1.000 77.82000  ? 276 PRO   C O   1 
ATOM   4067 C CB  . PRO   C 1 62  ? 34.14168  -25.53295 -56.77710 1.000 84.31000  ? 276 PRO   C CB  1 
ATOM   4068 C CG  . PRO   C 1 62  ? 33.02072  -26.29271 -57.42046 1.000 83.36000  ? 276 PRO   C CG  1 
ATOM   4069 C CD  . PRO   C 1 62  ? 31.78963  -25.98391 -56.55352 1.000 82.43000  ? 276 PRO   C CD  1 
ATOM   4070 N N   . GLU   C 1 63  ? 33.83188  -21.95886 -57.04009 1.000 80.02000  ? 277 GLU   C N   1 
ATOM   4071 C CA  . GLU   C 1 63  ? 33.66603  -20.79160 -57.90077 1.000 76.69000  ? 277 GLU   C CA  1 
ATOM   4072 C C   . GLU   C 1 63  ? 34.89015  -20.65240 -58.78158 1.000 81.56000  ? 277 GLU   C C   1 
ATOM   4073 O O   . GLU   C 1 63  ? 35.87013  -19.99755 -58.42227 1.000 92.45000  ? 277 GLU   C O   1 
ATOM   4074 C CB  . GLU   C 1 63  ? 33.43599  -19.54583 -57.06043 1.000 79.62000  ? 277 GLU   C CB  1 
ATOM   4075 C CG  . GLU   C 1 63  ? 32.08092  -19.55295 -56.44260 1.000 71.78000  ? 277 GLU   C CG  1 
ATOM   4076 C CD  . GLU   C 1 63  ? 31.00705  -19.11162 -57.42060 1.000 74.08000  ? 277 GLU   C CD  1 
ATOM   4077 O OE1 . GLU   C 1 63  ? 30.44810  -19.96137 -58.16391 1.000 69.72000  ? 277 GLU   C OE1 1 
ATOM   4078 O OE2 . GLU   C 1 63  ? 30.70311  -17.90161 -57.40728 1.000 75.75000  ? 277 GLU   C OE2 1 
ATOM   4079 N N   . LYS   C 1 64  ? 34.82326  -21.26605 -59.95077 1.000 81.83000  ? 278 LYS   C N   1 
ATOM   4080 C CA  . LYS   C 1 64  ? 35.90538  -21.20582 -60.90862 1.000 83.53000  ? 278 LYS   C CA  1 
ATOM   4081 C C   . LYS   C 1 64  ? 35.29156  -20.85040 -62.26059 1.000 83.36000  ? 278 LYS   C C   1 
ATOM   4082 O O   . LYS   C 1 64  ? 34.11059  -20.49331 -62.36563 1.000 78.83000  ? 278 LYS   C O   1 
ATOM   4083 C CB  . LYS   C 1 64  ? 36.67032  -22.54085 -60.90992 1.000 85.89000  ? 278 LYS   C CB  1 
ATOM   4084 C CG  . LYS   C 1 64  ? 37.52915  -22.78826 -59.66189 1.000 78.70000  ? 278 LYS   C CG  1 
ATOM   4085 C CD  . LYS   C 1 64  ? 38.36517  -21.57641 -59.29744 1.000 81.22000  ? 278 LYS   C CD  1 
ATOM   4086 C CE  . LYS   C 1 64  ? 39.26433  -21.14411 -60.45220 1.000 94.12000  ? 278 LYS   C CE  1 
ATOM   4087 N NZ  . LYS   C 1 64  ? 39.59138  -19.69114 -60.37874 1.000 94.46000  ? 278 LYS   C NZ  1 
ATOM   4088 N N   . LYS   C 1 65  ? 36.09368  -20.93112 -63.31152 1.000 82.74000  ? 279 LYS   C N   1 
ATOM   4089 C CA  . LYS   C 1 65  ? 35.49384  -20.93671 -64.62959 1.000 79.10000  ? 279 LYS   C CA  1 
ATOM   4090 C C   . LYS   C 1 65  ? 34.62679  -22.18664 -64.72006 1.000 78.21000  ? 279 LYS   C C   1 
ATOM   4091 O O   . LYS   C 1 65  ? 34.99468  -23.24981 -64.20533 1.000 74.09000  ? 279 LYS   C O   1 
ATOM   4092 C CB  . LYS   C 1 65  ? 36.56997  -20.89144 -65.72345 1.000 78.05000  ? 279 LYS   C CB  1 
ATOM   4093 C CG  . LYS   C 1 65  ? 37.80397  -20.02560 -65.38505 1.000 78.13000  ? 279 LYS   C CG  1 
ATOM   4094 C CD  . LYS   C 1 65  ? 37.46099  -18.57970 -64.98367 1.000 75.77000  ? 279 LYS   C CD  1 
ATOM   4095 C CE  . LYS   C 1 65  ? 37.18717  -17.69233 -66.18044 1.000 69.53000  ? 279 LYS   C CE  1 
ATOM   4096 N NZ  . LYS   C 1 65  ? 38.35129  -17.56211 -67.11926 1.000 66.77000  ? 279 LYS   C NZ  1 
ATOM   4097 N N   . GLY   C 1 66  ? 33.44287  -22.04241 -65.32616 1.000 73.88000  ? 280 GLY   C N   1 
ATOM   4098 C CA  . GLY   C 1 66  ? 32.42982  -23.07038 -65.27159 1.000 67.95000  ? 280 GLY   C CA  1 
ATOM   4099 C C   . GLY   C 1 66  ? 31.66166  -23.10173 -63.97269 1.000 72.60000  ? 280 GLY   C C   1 
ATOM   4100 O O   . GLY   C 1 66  ? 30.81160  -23.99074 -63.79305 1.000 64.39000  ? 280 GLY   C O   1 
ATOM   4101 N N   . GLY   C 1 67  ? 31.92959  -22.14201 -63.05438 1.000 70.92000  ? 281 GLY   C N   1 
ATOM   4102 C CA  . GLY   C 1 67  ? 31.28244  -22.11736 -61.76145 1.000 66.04000  ? 281 GLY   C CA  1 
ATOM   4103 C C   . GLY   C 1 67  ? 29.84447  -21.62628 -61.80048 1.000 56.76000  ? 281 GLY   C C   1 
ATOM   4104 O O   . GLY   C 1 67  ? 29.30061  -21.24195 -62.83143 1.000 56.56000  ? 281 GLY   C O   1 
ATOM   4105 N N   . LEU   C 1 68  ? 29.22832  -21.62160 -60.61955 1.000 58.93000  ? 282 LEU   C N   1 
ATOM   4106 C CA  . LEU   C 1 68  ? 27.83533  -21.19957 -60.49459 1.000 55.20000  ? 282 LEU   C CA  1 
ATOM   4107 C C   . LEU   C 1 68  ? 27.66643  -19.71547 -60.79518 1.000 55.44000  ? 282 LEU   C C   1 
ATOM   4108 O O   . LEU   C 1 68  ? 26.65752  -19.30725 -61.38918 1.000 51.37000  ? 282 LEU   C O   1 
ATOM   4109 C CB  . LEU   C 1 68  ? 27.32914  -21.51596 -59.09075 1.000 53.44000  ? 282 LEU   C CB  1 
ATOM   4110 C CG  . LEU   C 1 68  ? 25.91513  -21.04098 -58.78678 1.000 54.48000  ? 282 LEU   C CG  1 
ATOM   4111 C CD1 . LEU   C 1 68  ? 24.87918  -21.92372 -59.50416 1.000 46.39000  ? 282 LEU   C CD1 1 
ATOM   4112 C CD2 . LEU   C 1 68  ? 25.71595  -21.01141 -57.28679 1.000 52.55000  ? 282 LEU   C CD2 1 
ATOM   4113 N N   . LYS   C 1 69  ? 28.64642  -18.89364 -60.39182 1.000 52.95000  ? 283 LYS   C N   1 
ATOM   4114 C CA  . LYS   C 1 69  ? 28.58852  -17.45755 -60.66540 1.000 56.59000  ? 283 LYS   C CA  1 
ATOM   4115 C C   . LYS   C 1 69  ? 28.67471  -17.15812 -62.16131 1.000 57.69000  ? 283 LYS   C C   1 
ATOM   4116 O O   . LYS   C 1 69  ? 27.95282  -16.29294 -62.67014 1.000 58.83000  ? 283 LYS   C O   1 
ATOM   4117 C CB  . LYS   C 1 69  ? 29.70146  -16.75583 -59.89107 1.000 56.38000  ? 283 LYS   C CB  1 
ATOM   4118 C CG  . LYS   C 1 69  ? 29.92756  -15.27576 -60.18060 1.000 61.03000  ? 283 LYS   C CG  1 
ATOM   4119 C CD  . LYS   C 1 69  ? 30.81546  -14.67812 -59.07632 1.000 48.64000  ? 283 LYS   C CD  1 
ATOM   4120 C CE  . LYS   C 1 69  ? 31.62457  -13.45803 -59.51687 1.000 59.56000  ? 283 LYS   C CE  1 
ATOM   4121 N NZ  . LYS   C 1 69  ? 30.80667  -12.28087 -59.94162 1.000 57.96000  ? 283 LYS   C NZ  1 
ATOM   4122 N N   . GLU   C 1 70  ? 29.54777  -17.86195 -62.87741 1.000 59.03000  ? 284 GLU   C N   1 
ATOM   4123 C CA  . GLU   C 1 70  ? 29.66495  -17.67453 -64.32134 1.000 60.34000  ? 284 GLU   C CA  1 
ATOM   4124 C C   . GLU   C 1 70  ? 28.42201  -18.16727 -65.03463 1.000 52.09000  ? 284 GLU   C C   1 
ATOM   4125 O O   . GLU   C 1 70  ? 27.87515  -17.47599 -65.90350 1.000 52.41000  ? 284 GLU   C O   1 
ATOM   4126 C CB  . GLU   C 1 70  ? 30.90298  -18.41144 -64.81841 1.000 64.64000  ? 284 GLU   C CB  1 
ATOM   4127 C CG  . GLU   C 1 70  ? 31.04714  -18.59402 -66.28744 1.000 60.90000  ? 284 GLU   C CG  1 
ATOM   4128 C CD  . GLU   C 1 70  ? 32.40416  -19.19699 -66.61046 1.000 70.05000  ? 284 GLU   C CD  1 
ATOM   4129 O OE1 . GLU   C 1 70  ? 33.41714  -18.53814 -66.26614 1.000 66.21000  ? 284 GLU   C OE1 1 
ATOM   4130 O OE2 . GLU   C 1 70  ? 32.45417  -20.31382 -67.19178 1.000 74.06000  ? 284 GLU   C OE2 1 
ATOM   4131 N N   . LEU   C 1 71  ? 27.95991  -19.35835 -64.67304 1.000 51.82000  ? 285 LEU   C N   1 
ATOM   4132 C CA  . LEU   C 1 71  ? 26.72996  -19.88813 -65.23934 1.000 51.29000  ? 285 LEU   C CA  1 
ATOM   4133 C C   . LEU   C 1 71  ? 25.54897  -18.96016 -64.95921 1.000 51.59000  ? 285 LEU   C C   1 
ATOM   4134 O O   . LEU   C 1 71  ? 24.76409  -18.65386 -65.86022 1.000 53.19000  ? 285 LEU   C O   1 
ATOM   4135 C CB  . LEU   C 1 71  ? 26.46783  -21.27928 -64.67578 1.000 47.97000  ? 285 LEU   C CB  1 
ATOM   4136 C CG  . LEU   C 1 71  ? 27.28285  -22.40814 -65.28301 1.000 47.89000  ? 285 LEU   C CG  1 
ATOM   4137 C CD1 . LEU   C 1 71  ? 26.62674  -23.71522 -64.91447 1.000 48.96000  ? 285 LEU   C CD1 1 
ATOM   4138 C CD2 . LEU   C 1 71  ? 27.36203  -22.24971 -66.77796 1.000 45.64000  ? 285 LEU   C CD2 1 
ATOM   4139 N N   . TYR   C 1 72  ? 25.39484  -18.51852 -63.70910 1.000 47.68000  ? 286 TYR   C N   1 
ATOM   4140 C CA  . TYR   C 1 72  ? 24.29284  -17.61955 -63.40497 1.000 47.89000  ? 286 TYR   C CA  1 
ATOM   4141 C C   . TYR   C 1 72  ? 24.40500  -16.33033 -64.19158 1.000 46.37000  ? 286 TYR   C C   1 
ATOM   4142 O O   . TYR   C 1 72  ? 23.40508  -15.82513 -64.69855 1.000 51.06000  ? 286 TYR   C O   1 
ATOM   4143 C CB  . TYR   C 1 72  ? 24.21868  -17.31299 -61.90389 1.000 52.76000  ? 286 TYR   C CB  1 
ATOM   4144 C CG  . TYR   C 1 72  ? 22.92367  -16.63303 -61.55284 1.000 43.39000  ? 286 TYR   C CG  1 
ATOM   4145 C CD1 . TYR   C 1 72  ? 22.78374  -15.24900 -61.64146 1.000 39.84000  ? 286 TYR   C CD1 1 
ATOM   4146 C CD2 . TYR   C 1 72  ? 21.81359  -17.38408 -61.21120 1.000 50.58000  ? 286 TYR   C CD2 1 
ATOM   4147 C CE1 . TYR   C 1 72  ? 21.59173  -14.62903 -61.35542 1.000 39.72000  ? 286 TYR   C CE1 1 
ATOM   4148 C CE2 . TYR   C 1 72  ? 20.59258  -16.77411 -60.92017 1.000 49.10000  ? 286 TYR   C CE2 1 
ATOM   4149 C CZ  . TYR   C 1 72  ? 20.48965  -15.40108 -60.99678 1.000 46.93000  ? 286 TYR   C CZ  1 
ATOM   4150 O OH  . TYR   C 1 72  ? 19.27165  -14.83411 -60.72076 1.000 43.32000  ? 286 TYR   C OH  1 
ATOM   4151 N N   . GLU   C 1 73  ? 25.60503  -15.76635 -64.29227 1.000 49.45000  ? 287 GLU   C N   1 
ATOM   4152 C CA  . GLU   C 1 73  ? 25.77419  -14.54913 -65.08589 1.000 54.13000  ? 287 GLU   C CA  1 
ATOM   4153 C C   . GLU   C 1 73  ? 25.47135  -14.79568 -66.55700 1.000 48.94000  ? 287 GLU   C C   1 
ATOM   4154 O O   . GLU   C 1 73  ? 24.95147  -13.91146 -67.24780 1.000 46.06000  ? 287 GLU   C O   1 
ATOM   4155 C CB  . GLU   C 1 73  ? 27.19019  -13.99925 -64.91156 1.000 50.73000  ? 287 GLU   C CB  1 
ATOM   4156 C CG  . GLU   C 1 73  ? 27.35907  -13.26263 -63.61732 1.000 55.98000  ? 287 GLU   C CG  1 
ATOM   4157 C CD  . GLU   C 1 73  ? 28.79502  -13.19483 -63.16913 1.000 64.38000  ? 287 GLU   C CD  1 
ATOM   4158 O OE1 . GLU   C 1 73  ? 29.67009  -13.66465 -63.93316 1.000 68.47000  ? 287 GLU   C OE1 1 
ATOM   4159 O OE2 . GLU   C 1 73  ? 29.04090  -12.73418 -62.02397 1.000 61.21000  ? 287 GLU   C OE2 1 
ATOM   4160 N N   . LYS   C 1 74  ? 25.79136  -15.99155 -67.05231 1.000 48.35000  ? 288 LYS   C N   1 
ATOM   4161 C CA  . LYS   C 1 74  ? 25.50251  -16.34914 -68.43845 1.000 43.62000  ? 288 LYS   C CA  1 
ATOM   4162 C C   . LYS   C 1 74  ? 24.00553  -16.50000 -68.66268 1.000 47.46000  ? 288 LYS   C C   1 
ATOM   4163 O O   . LYS   C 1 74  ? 23.50167  -16.24465 -69.76366 1.000 56.77000  ? 288 LYS   C O   1 
ATOM   4164 C CB  . LYS   C 1 74  ? 26.27449  -17.62607 -68.76873 1.000 51.07000  ? 288 LYS   C CB  1 
ATOM   4165 C CG  . LYS   C 1 74  ? 26.26063  -18.15466 -70.19389 1.000 53.51000  ? 288 LYS   C CG  1 
ATOM   4166 C CD  . LYS   C 1 74  ? 26.99457  -19.51668 -70.22120 1.000 55.86000  ? 288 LYS   C CD  1 
ATOM   4167 C CE  . LYS   C 1 74  ? 26.82070  -20.27129 -71.53844 1.000 65.39000  ? 288 LYS   C CE  1 
ATOM   4168 N NZ  . LYS   C 1 74  ? 25.39672  -20.60713 -71.84671 1.000 73.51000  ? 288 LYS   C NZ  1 
ATOM   4169 N N   . GLY   C 1 75  ? 23.27238  -16.87827 -67.63487 1.000 47.08000  ? 289 GLY   C N   1 
ATOM   4170 C CA  . GLY   C 1 75  ? 21.84239  -16.99617 -67.74008 1.000 46.51000  ? 289 GLY   C CA  1 
ATOM   4171 C C   . GLY   C 1 75  ? 21.44244  -18.19991 -68.56248 1.000 47.48000  ? 289 GLY   C C   1 
ATOM   4172 O O   . GLY   C 1 75  ? 22.28244  -19.02984 -68.94062 1.000 48.01000  ? 289 GLY   C O   1 
ATOM   4173 N N   . PRO   C 1 76  ? 20.12746  -18.34378 -68.82368 1.000 51.15000  ? 290 PRO   C N   1 
ATOM   4174 C CA  . PRO   C 1 76  ? 19.01644  -17.50587 -68.33457 1.000 46.60000  ? 290 PRO   C CA  1 
ATOM   4175 C C   . PRO   C 1 76  ? 18.71425  -17.69428 -66.86266 1.000 48.62000  ? 290 PRO   C C   1 
ATOM   4176 O O   . PRO   C 1 76  ? 18.70214  -18.80443 -66.35899 1.000 50.74000  ? 290 PRO   C O   1 
ATOM   4177 C CB  . PRO   C 1 76  ? 17.83752  -17.96756 -69.18285 1.000 37.29000  ? 290 PRO   C CB  1 
ATOM   4178 C CG  . PRO   C 1 76  ? 18.12849  -19.40549 -69.48023 1.000 40.13000  ? 290 PRO   C CG  1 
ATOM   4179 C CD  . PRO   C 1 76  ? 19.63248  -19.56056 -69.49310 1.000 51.78000  ? 290 PRO   C CD  1 
ATOM   4180 N N   . PRO   C 1 77  ? 18.42822  -16.58247 -66.17937 1.000 54.84000  ? 291 PRO   C N   1 
ATOM   4181 C CA  . PRO   C 1 77  ? 18.20205  -16.63789 -64.71741 1.000 49.37000  ? 291 PRO   C CA  1 
ATOM   4182 C C   . PRO   C 1 77  ? 17.00895  -17.48296 -64.28380 1.000 47.95000  ? 291 PRO   C C   1 
ATOM   4183 O O   . PRO   C 1 77  ? 16.98679  -17.96130 -63.13895 1.000 49.60000  ? 291 PRO   C O   1 
ATOM   4184 C CB  . PRO   C 1 77  ? 17.98507  -15.16299 -64.34401 1.000 46.68000  ? 291 PRO   C CB  1 
ATOM   4185 C CG  . PRO   C 1 77  ? 18.66424  -14.39570 -65.44170 1.000 52.54000  ? 291 PRO   C CG  1 
ATOM   4186 C CD  . PRO   C 1 77  ? 18.44235  -15.19932 -66.69196 1.000 49.34000  ? 291 PRO   C CD  1 
ATOM   4187 N N   . ASN   C 1 78  ? 15.99805  -17.65267 -65.13698 1.000 51.71000  ? 292 ASN   C N   1 
ATOM   4188 C CA  . ASN   C 1 78  ? 14.83396  -18.43573 -64.73535 1.000 46.70000  ? 292 ASN   C CA  1 
ATOM   4189 C C   . ASN   C 1 78  ? 15.09290  -19.92972 -64.80675 1.000 45.45000  ? 292 ASN   C C   1 
ATOM   4190 O O   . ASN   C 1 78  ? 14.15884  -20.71074 -64.60709 1.000 43.81000  ? 292 ASN   C O   1 
ATOM   4191 C CB  . ASN   C 1 78  ? 13.60908  -18.10142 -65.59439 1.000 41.76000  ? 292 ASN   C CB  1 
ATOM   4192 C CG  . ASN   C 1 78  ? 13.91226  -18.14400 -67.08637 1.000 47.97000  ? 292 ASN   C CG  1 
ATOM   4193 O OD1 . ASN   C 1 78  ? 15.07531  -18.06193 -67.50421 1.000 48.38000  ? 292 ASN   C OD1 1 
ATOM   4194 N ND2 . ASN   C 1 78  ? 12.86535  -18.30271 -67.89854 1.000 46.52000  ? 292 ASN   C ND2 1 
ATOM   4195 N N   . ALA   C 1 79  ? 16.31992  -20.34969 -65.09673 1.000 41.98000  ? 293 ALA   C N   1 
ATOM   4196 C CA  . ALA   C 1 79  ? 16.65286  -21.76071 -65.10210 1.000 45.72000  ? 293 ALA   C CA  1 
ATOM   4197 C C   . ALA   C 1 79  ? 17.42369  -22.19611 -63.86114 1.000 46.32000  ? 293 ALA   C C   1 
ATOM   4198 O O   . ALA   C 1 79  ? 17.85563  -23.35314 -63.79642 1.000 48.58000  ? 293 ALA   C O   1 
ATOM   4199 C CB  . ALA   C 1 79  ? 17.44599  -22.10737 -66.36811 1.000 46.34000  ? 293 ALA   C CB  1 
ATOM   4200 N N   . PHE   C 1 80  ? 17.55861  -21.32641 -62.85786 1.000 46.44000  ? 294 PHE   C N   1 
ATOM   4201 C CA  . PHE   C 1 80  ? 18.43946  -21.57078 -61.72083 1.000 48.83000  ? 294 PHE   C CA  1 
ATOM   4202 C C   . PHE   C 1 80  ? 17.65629  -21.81512 -60.42900 1.000 46.47000  ? 294 PHE   C C   1 
ATOM   4203 O O   . PHE   C 1 80  ? 16.90528  -20.94622 -59.97083 1.000 49.09000  ? 294 PHE   C O   1 
ATOM   4204 C CB  . PHE   C 1 80  ? 19.41449  -20.40887 -61.56637 1.000 46.80000  ? 294 PHE   C CB  1 
ATOM   4205 C CG  . PHE   C 1 80  ? 20.55461  -20.44863 -62.55625 1.000 47.89000  ? 294 PHE   C CG  1 
ATOM   4206 C CD1 . PHE   C 1 80  ? 20.41879  -19.91325 -63.82511 1.000 47.03000  ? 294 PHE   C CD1 1 
ATOM   4207 C CD2 . PHE   C 1 80  ? 21.76054  -21.05179 -62.21728 1.000 46.33000  ? 294 PHE   C CD2 1 
ATOM   4208 C CE1 . PHE   C 1 80  ? 21.47789  -19.96004 -64.72099 1.000 50.46000  ? 294 PHE   C CE1 1 
ATOM   4209 C CE2 . PHE   C 1 80  ? 22.81765  -21.08958 -63.10016 1.000 42.46000  ? 294 PHE   C CE2 1 
ATOM   4210 C CZ  . PHE   C 1 80  ? 22.68182  -20.55120 -64.34702 1.000 45.61000  ? 294 PHE   C CZ  1 
ATOM   4211 N N   . PHE   C 1 81  ? 17.85917  -22.98931 -59.82832 1.000 46.33000  ? 295 PHE   C N   1 
ATOM   4212 C CA  . PHE   C 1 81  ? 17.07701  -23.42161 -58.67554 1.000 44.45000  ? 295 PHE   C CA  1 
ATOM   4213 C C   . PHE   C 1 81  ? 17.99485  -24.04596 -57.63361 1.000 46.70000  ? 295 PHE   C C   1 
ATOM   4214 O O   . PHE   C 1 81  ? 18.95986  -24.73790 -57.96970 1.000 50.02000  ? 295 PHE   C O   1 
ATOM   4215 C CB  . PHE   C 1 81  ? 16.01201  -24.45645 -59.06397 1.000 41.07000  ? 295 PHE   C CB  1 
ATOM   4216 C CG  . PHE   C 1 81  ? 14.95014  -23.92014 -59.95194 1.000 47.87000  ? 295 PHE   C CG  1 
ATOM   4217 C CD1 . PHE   C 1 81  ? 15.15931  -23.83575 -61.31889 1.000 43.91000  ? 295 PHE   C CD1 1 
ATOM   4218 C CD2 . PHE   C 1 81  ? 13.72109  -23.52823 -59.43697 1.000 50.72000  ? 295 PHE   C CD2 1 
ATOM   4219 C CE1 . PHE   C 1 81  ? 14.17943  -23.34146 -62.14786 1.000 44.65000  ? 295 PHE   C CE1 1 
ATOM   4220 C CE2 . PHE   C 1 81  ? 12.73322  -23.04894 -60.26895 1.000 46.97000  ? 295 PHE   C CE2 1 
ATOM   4221 C CZ  . PHE   C 1 81  ? 12.97038  -22.94756 -61.62589 1.000 47.18000  ? 295 PHE   C CZ  1 
ATOM   4222 N N   . LEU   C 1 82  ? 17.66371  -23.81131 -56.36658 1.000 42.72000  ? 296 LEU   C N   1 
ATOM   4223 C CA  . LEU   C 1 82  ? 18.36055  -24.36768 -55.21366 1.000 41.64000  ? 296 LEU   C CA  1 
ATOM   4224 C C   . LEU   C 1 82  ? 17.43542  -25.34285 -54.49906 1.000 45.97000  ? 296 LEU   C C   1 
ATOM   4225 O O   . LEU   C 1 82  ? 16.26340  -25.02187 -54.23910 1.000 46.51000  ? 296 LEU   C O   1 
ATOM   4226 C CB  . LEU   C 1 82  ? 18.79048  -23.25498 -54.25828 1.000 38.36000  ? 296 LEU   C CB  1 
ATOM   4227 C CG  . LEU   C 1 82  ? 19.02729  -23.71041 -52.82139 1.000 41.12000  ? 296 LEU   C CG  1 
ATOM   4228 C CD1 . LEU   C 1 82  ? 20.23924  -24.61448 -52.77450 1.000 45.32000  ? 296 LEU   C CD1 1 
ATOM   4229 C CD2 . LEU   C 1 82  ? 19.20523  -22.52770 -51.86302 1.000 39.49000  ? 296 LEU   C CD2 1 
ATOM   4230 N N   . VAL   C 1 83  ? 17.95032  -26.52897 -54.18134 1.000 38.07000  ? 297 VAL   C N   1 
ATOM   4231 C CA  . VAL   C 1 83  ? 17.20019  -27.52115 -53.42172 1.000 45.70000  ? 297 VAL   C CA  1 
ATOM   4232 C C   . VAL   C 1 83  ? 17.99402  -27.87356 -52.17173 1.000 50.59000  ? 297 VAL   C C   1 
ATOM   4233 O O   . VAL   C 1 83  ? 19.17901  -28.23859 -52.25869 1.000 48.57000  ? 297 VAL   C O   1 
ATOM   4234 C CB  . VAL   C 1 83  ? 16.90523  -28.78290 -54.25313 1.000 46.25000  ? 297 VAL   C CB  1 
ATOM   4235 C CG1 . VAL   C 1 83  ? 16.55406  -29.94915 -53.34151 1.000 42.18000  ? 297 VAL   C CG1 1 
ATOM   4236 C CG2 . VAL   C 1 83  ? 15.78336  -28.50656 -55.21218 1.000 40.33000  ? 297 VAL   C CG2 1 
ATOM   4237 N N   . LYS   C 1 84  ? 17.35689  -27.72587 -51.01076 1.000 39.96000  ? 298 LYS   C N   1 
ATOM   4238 C CA  . LYS   C 1 84  ? 17.93271  -28.17126 -49.74882 1.000 42.66000  ? 298 LYS   C CA  1 
ATOM   4239 C C   . LYS   C 1 84  ? 17.24461  -29.46735 -49.35129 1.000 46.65000  ? 298 LYS   C C   1 
ATOM   4240 O O   . LYS   C 1 84  ? 16.03557  -29.48037 -49.08344 1.000 50.58000  ? 298 LYS   C O   1 
ATOM   4241 C CB  . LYS   C 1 84  ? 17.77863  -27.12158 -48.64754 1.000 44.85000  ? 298 LYS   C CB  1 
ATOM   4242 C CG  . LYS   C 1 84  ? 18.13844  -27.62901 -47.24764 1.000 45.19000  ? 298 LYS   C CG  1 
ATOM   4243 C CD  . LYS   C 1 84  ? 18.73138  -26.52730 -46.35125 1.000 46.54000  ? 298 LYS   C CD  1 
ATOM   4244 C CE  . LYS   C 1 84  ? 19.22620  -27.09271 -45.01535 1.000 49.25000  ? 298 LYS   C CE  1 
ATOM   4245 N NZ  . LYS   C 1 84  ? 19.20211  -26.08503 -43.90806 1.000 46.53000  ? 298 LYS   C NZ  1 
ATOM   4246 N N   . PHE   C 1 85  ? 18.00456  -30.55039 -49.33251 1.000 47.17000  ? 299 PHE   C N   1 
ATOM   4247 C CA  . PHE   C 1 85  ? 17.49545  -31.84949 -48.92095 1.000 49.17000  ? 299 PHE   C CA  1 
ATOM   4248 C C   . PHE   C 1 85  ? 17.81826  -32.06793 -47.44698 1.000 48.81000  ? 299 PHE   C C   1 
ATOM   4249 O O   . PHE   C 1 85  ? 18.84622  -31.59113 -46.94872 1.000 43.43000  ? 299 PHE   C O   1 
ATOM   4250 C CB  . PHE   C 1 85  ? 18.12250  -32.96727 -49.75721 1.000 47.14000  ? 299 PHE   C CB  1 
ATOM   4251 C CG  . PHE   C 1 85  ? 17.39364  -33.26086 -51.03538 1.000 45.57000  ? 299 PHE   C CG  1 
ATOM   4252 C CD1 . PHE   C 1 85  ? 16.04762  -33.56680 -51.03663 1.000 49.63000  ? 299 PHE   C CD1 1 
ATOM   4253 C CD2 . PHE   C 1 85  ? 18.07778  -33.22554 -52.25029 1.000 47.99000  ? 299 PHE   C CD2 1 
ATOM   4254 C CE1 . PHE   C 1 85  ? 15.39075  -33.84142 -52.23279 1.000 55.05000  ? 299 PHE   C CE1 1 
ATOM   4255 C CE2 . PHE   C 1 85  ? 17.43991  -33.47816 -53.44244 1.000 41.42000  ? 299 PHE   C CE2 1 
ATOM   4256 C CZ  . PHE   C 1 85  ? 16.10190  -33.79410 -53.44569 1.000 51.42000  ? 299 PHE   C CZ  1 
ATOM   4257 N N   . TRP   C 1 86  ? 16.91614  -32.76610 -46.74929 1.000 46.64000  ? 300 TRP   C N   1 
ATOM   4258 C CA  . TRP   C 1 86  ? 17.19196  -33.41049 -45.46045 1.000 45.28000  ? 300 TRP   C CA  1 
ATOM   4259 C C   . TRP   C 1 86  ? 17.11792  -34.91341 -45.72090 1.000 46.68000  ? 300 TRP   C C   1 
ATOM   4260 O O   . TRP   C 1 86  ? 16.02390  -35.48434 -45.77320 1.000 45.66000  ? 300 TRP   C O   1 
ATOM   4261 C CB  . TRP   C 1 86  ? 16.18785  -32.98775 -44.38744 1.000 47.63000  ? 300 TRP   C CB  1 
ATOM   4262 C CG  . TRP   C 1 86  ? 16.42183  -31.66095 -43.74103 1.000 46.99000  ? 300 TRP   C CG  1 
ATOM   4263 C CD1 . TRP   C 1 86  ? 17.00570  -31.44633 -42.53889 1.000 45.75000  ? 300 TRP   C CD1 1 
ATOM   4264 C CD2 . TRP   C 1 86  ? 16.03695  -30.36979 -44.23670 1.000 47.23000  ? 300 TRP   C CD2 1 
ATOM   4265 N NE1 . TRP   C 1 86  ? 17.05273  -30.10742 -42.26550 1.000 45.66000  ? 300 TRP   C NE1 1 
ATOM   4266 C CE2 . TRP   C 1 86  ? 16.45188  -29.41809 -43.28337 1.000 47.17000  ? 300 TRP   C CE2 1 
ATOM   4267 C CE3 . TRP   C 1 86  ? 15.41211  -29.92342 -45.40664 1.000 44.58000  ? 300 TRP   C CE3 1 
ATOM   4268 C CZ2 . TRP   C 1 86  ? 16.25196  -28.04303 -43.45299 1.000 44.34000  ? 300 TRP   C CZ2 1 
ATOM   4269 C CZ3 . TRP   C 1 86  ? 15.19919  -28.56036 -45.56727 1.000 44.72000  ? 300 TRP   C CZ3 1 
ATOM   4270 C CH2 . TRP   C 1 86  ? 15.62912  -27.63567 -44.59294 1.000 43.85000  ? 300 TRP   C CH2 1 
ATOM   4271 N N   . ALA   C 1 87  ? 18.27291  -35.54740 -45.91394 1.000 45.65000  ? 301 ALA   C N   1 
ATOM   4272 C CA  . ALA   C 1 87  ? 18.27791  -36.92927 -46.38035 1.000 50.13000  ? 301 ALA   C CA  1 
ATOM   4273 C C   . ALA   C 1 87  ? 17.90573  -37.89358 -45.25568 1.000 53.02000  ? 301 ALA   C C   1 
ATOM   4274 O O   . ALA   C 1 87  ? 18.10360  -37.61893 -44.08057 1.000 51.42000  ? 301 ALA   C O   1 
ATOM   4275 C CB  . ALA   C 1 87  ? 19.64296  -37.29816 -46.96129 1.000 43.16000  ? 301 ALA   C CB  1 
ATOM   4276 N N   . ASP   C 1 88  ? 17.34372  -39.03544 -45.64008 1.000 56.43000  ? 302 ASP   C N   1 
ATOM   4277 C CA  . ASP   C 1 88  ? 17.08256  -40.14669 -44.73243 1.000 56.06000  ? 302 ASP   C CA  1 
ATOM   4278 C C   . ASP   C 1 88  ? 18.27153  -41.09373 -44.80557 1.000 58.48000  ? 302 ASP   C C   1 
ATOM   4279 O O   . ASP   C 1 88  ? 18.51962  -41.70243 -45.84672 1.000 65.69000  ? 302 ASP   C O   1 
ATOM   4280 C CB  . ASP   C 1 88  ? 15.78757  -40.85752 -45.11880 1.000 57.43000  ? 302 ASP   C CB  1 
ATOM   4281 C CG  . ASP   C 1 88  ? 15.40941  -41.95678 -44.16217 1.000 61.23000  ? 302 ASP   C CG  1 
ATOM   4282 O OD1 . ASP   C 1 88  ? 16.15228  -42.22610 -43.21716 1.000 76.72000  ? 302 ASP   C OD1 1 
ATOM   4283 O OD2 . ASP   C 1 88  ? 14.36140  -42.58068 -44.36347 1.000 70.17000  ? 302 ASP   C OD2 1 
ATOM   4284 N N   . LEU   C 1 89  ? 18.94938  -41.27409 -43.69054 1.000 58.84000  ? 303 LEU   C N   1 
ATOM   4285 C CA  . LEU   C 1 89  ? 20.07134  -42.18115 -43.66267 1.000 62.89000  ? 303 LEU   C CA  1 
ATOM   4286 C C   . LEU   C 1 89  ? 19.81118  -43.40738 -42.82506 1.000 74.96000  ? 303 LEU   C C   1 
ATOM   4287 O O   . LEU   C 1 89  ? 20.75509  -44.01356 -42.33813 1.000 79.69000  ? 303 LEU   C O   1 
ATOM   4288 C CB  . LEU   C 1 89  ? 21.30731  -41.47336 -43.13232 1.000 61.71000  ? 303 LEU   C CB  1 
ATOM   4289 C CG  . LEU   C 1 89  ? 22.22346  -40.75811 -44.12200 1.000 62.70000  ? 303 LEU   C CG  1 
ATOM   4290 C CD1 . LEU   C 1 89  ? 23.26241  -39.94338 -43.37263 1.000 59.53000  ? 303 LEU   C CD1 1 
ATOM   4291 C CD2 . LEU   C 1 89  ? 22.89652  -41.76987 -45.03221 1.000 59.00000  ? 303 LEU   C CD2 1 
ATOM   4292 N N   . ASN   C 1 90  ? 18.56415  -43.81736 -42.69533 1.000 72.34000  ? 304 ASN   C N   1 
ATOM   4293 C CA  . ASN   C 1 90  ? 18.25600  -44.99757 -41.93671 1.000 74.17000  ? 304 ASN   C CA  1 
ATOM   4294 C C   . ASN   C 1 90  ? 17.99706  -46.17029 -42.84909 1.000 77.51000  ? 304 ASN   C C   1 
ATOM   4295 O O   . ASN   C 1 90  ? 16.86009  -46.40012 -43.23629 1.000 80.83000  ? 304 ASN   C O   1 
ATOM   4296 C CB  . ASN   C 1 90  ? 17.02691  -44.73976 -41.09179 1.000 78.54000  ? 304 ASN   C CB  1 
ATOM   4297 C CG  . ASN   C 1 90  ? 17.16486  -43.50702 -40.21741 1.000 91.25000  ? 304 ASN   C CG  1 
ATOM   4298 O OD1 . ASN   C 1 90  ? 16.16784  -42.90809 -39.81635 1.000 89.92000  ? 304 ASN   C OD1 1 
ATOM   4299 N ND2 . ASN   C 1 90  ? 18.39985  -43.12217 -39.92015 1.000 93.96000  ? 304 ASN   C ND2 1 
ATOM   4300 N N   . SER   C 1 91  ? 19.02206  -46.94524 -43.18619 1.000 79.65000  ? 305 SER   C N   1 
ATOM   4301 C CA  . SER   C 1 91  ? 18.78013  -48.00894 -44.14653 1.000 88.05000  ? 305 SER   C CA  1 
ATOM   4302 C C   . SER   C 1 91  ? 19.68105  -49.18006 -43.90377 1.000 100.02000 ? 305 SER   C C   1 
ATOM   4303 O O   . SER   C 1 91  ? 20.25991  -49.30640 -42.83274 1.000 102.16000 ? 305 SER   C O   1 
ATOM   4304 C CB  . SER   C 1 91  ? 18.99232  -47.53654 -45.57437 1.000 86.77000  ? 305 SER   C CB  1 
ATOM   4305 O OG  . SER   C 1 91  ? 20.34337  -47.24252 -45.83012 1.000 83.66000  ? 305 SER   C OG  1 
ATOM   4306 N N   . THR   C 1 92  ? 19.77812  -50.04977 -44.89301 1.000 102.49000 ? 306 THR   C N   1 
ATOM   4307 C CA  . THR   C 1 92  ? 20.65806  -51.22084 -44.81525 1.000 106.03000 ? 306 THR   C CA  1 
ATOM   4308 C C   . THR   C 1 92  ? 20.23189  -52.11214 -43.70956 1.000 111.32000 ? 306 THR   C C   1 
ATOM   4309 O O   . THR   C 1 92  ? 20.93080  -53.04728 -43.34775 1.000 114.13000 ? 306 THR   C O   1 
ATOM   4310 C CB  . THR   C 1 92  ? 22.16105  -50.90096 -44.63597 1.000 109.00000 ? 306 THR   C CB  1 
ATOM   4311 O OG1 . THR   C 1 92  ? 22.43291  -50.55437 -43.27084 1.000 110.31000 ? 306 THR   C OG1 1 
ATOM   4312 C CG2 . THR   C 1 92  ? 22.61022  -49.78170 -45.57959 1.000 112.38000 ? 306 THR   C CG2 1 
ATOM   4313 N N   . ILE   C 1 93  ? 19.08783  -51.81126 -43.13261 1.000 113.23000 ? 307 ILE   C N   1 
ATOM   4314 C CA  . ILE   C 1 93  ? 18.60967  -52.71152 -42.14393 1.000 111.66000 ? 307 ILE   C CA  1 
ATOM   4315 C C   . ILE   C 1 93  ? 18.36171  -53.94228 -42.95132 1.000 114.58000 ? 307 ILE   C C   1 
ATOM   4316 O O   . ILE   C 1 93  ? 17.84785  -53.86093 -44.06536 1.000 116.79000 ? 307 ILE   C O   1 
ATOM   4317 C CB  . ILE   C 1 93  ? 17.32162  -52.21166 -41.49094 1.000 111.33000 ? 307 ILE   C CB  1 
ATOM   4318 C CG1 . ILE   C 1 93  ? 16.39077  -51.59131 -42.53587 1.000 98.89000  ? 307 ILE   C CG1 1 
ATOM   4319 C CG2 . ILE   C 1 93  ? 17.64353  -51.18999 -40.41560 1.000 110.74000 ? 307 ILE   C CG2 1 
ATOM   4320 C CD1 . ILE   C 1 93  ? 16.57786  -50.10126 -42.73541 1.000 90.94000  ? 307 ILE   C CD1 1 
ATOM   4321 N N   . GLN   C 1 94  ? 18.75159  -55.08545 -42.41561 1.000 112.82000 ? 308 GLN   C N   1 
ATOM   4322 C CA  . GLN   C 1 94  ? 18.47562  -56.31924 -43.10101 1.000 111.50000 ? 308 GLN   C CA  1 
ATOM   4323 C C   . GLN   C 1 94  ? 19.03379  -56.16486 -44.47689 1.000 113.22000 ? 308 GLN   C C   1 
ATOM   4324 O O   . GLN   C 1 94  ? 18.39889  -56.56855 -45.44309 1.000 112.86000 ? 308 GLN   C O   1 
ATOM   4325 C CB  . GLN   C 1 94  ? 16.98861  -56.60716 -43.14127 1.000 109.13000 ? 308 GLN   C CB  1 
ATOM   4326 C CG  . GLN   C 1 94  ? 16.35044  -56.76453 -41.77339 1.000 114.18000 ? 308 GLN   C CG  1 
ATOM   4327 C CD  . GLN   C 1 94  ? 15.62644  -55.51363 -41.32411 1.000 118.52000 ? 308 GLN   C CD  1 
ATOM   4328 O OE1 . GLN   C 1 94  ? 15.37458  -54.61238 -42.12188 1.000 117.10000 ? 308 GLN   C OE1 1 
ATOM   4329 N NE2 . GLN   C 1 94  ? 15.27529  -55.45598 -40.04614 1.000 115.91000 ? 308 GLN   C NE2 1 
ATOM   4330 N N   . GLU   C 1 95  ? 20.22183  -55.58888 -44.59958 1.000 113.29000 ? 309 GLU   C N   1 
ATOM   4331 C CA  . GLU   C 1 95  ? 20.68401  -55.33651 -45.93645 1.000 107.73000 ? 309 GLU   C CA  1 
ATOM   4332 C C   . GLU   C 1 95  ? 21.40601  -56.51939 -46.45971 1.000 112.76000 ? 309 GLU   C C   1 
ATOM   4333 O O   . GLU   C 1 95  ? 22.46394  -56.89058 -45.95569 1.000 111.37000 ? 309 GLU   C O   1 
ATOM   4334 C CB  . GLU   C 1 95  ? 21.65906  -54.16955 -45.94599 1.000 101.89000 ? 309 GLU   C CB  1 
ATOM   4335 C CG  . GLU   C 1 95  ? 22.19924  -53.79117 -47.31082 1.000 96.69000  ? 309 GLU   C CG  1 
ATOM   4336 C CD  . GLU   C 1 95  ? 23.43027  -52.91526 -47.20741 1.000 96.71000  ? 309 GLU   C CD  1 
ATOM   4337 O OE1 . GLU   C 1 95  ? 24.09814  -52.96460 -46.15535 1.000 93.19000  ? 309 GLU   C OE1 1 
ATOM   4338 O OE2 . GLU   C 1 95  ? 23.74042  -52.18499 -48.17016 1.000 89.74000  ? 309 GLU   C OE2 1 
ATOM   4339 N N   . GLY   C 1 96  ? 20.84911  -57.12206 -47.48996 1.000 108.48000 ? 310 GLY   C N   1 
ATOM   4340 C CA  . GLY   C 1 96  ? 21.53314  -58.20090 -48.14419 1.000 103.83000 ? 310 GLY   C CA  1 
ATOM   4341 C C   . GLY   C 1 96  ? 22.67626  -57.59073 -48.90587 1.000 97.61000  ? 310 GLY   C C   1 
ATOM   4342 O O   . GLY   C 1 96  ? 22.58637  -56.45559 -49.36255 1.000 95.40000  ? 310 GLY   C O   1 
ATOM   4343 N N   . PRO   C 1 97  ? 23.76424  -58.32873 -49.05996 1.000 88.70000  ? 311 PRO   C N   1 
ATOM   4344 C CA  . PRO   C 1 97  ? 24.81737  -57.82253 -49.91968 1.000 84.29000  ? 311 PRO   C CA  1 
ATOM   4345 C C   . PRO   C 1 97  ? 24.12652  -57.94811 -51.24780 1.000 83.32000  ? 311 PRO   C C   1 
ATOM   4346 O O   . PRO   C 1 97  ? 23.20650  -58.75404 -51.36015 1.000 76.49000  ? 311 PRO   C O   1 
ATOM   4347 C CB  . PRO   C 1 97  ? 25.94030  -58.82364 -49.72284 1.000 80.68000  ? 311 PRO   C CB  1 
ATOM   4348 C CG  . PRO   C 1 97  ? 25.71111  -59.37003 -48.35903 1.000 83.09000  ? 311 PRO   C CG  1 
ATOM   4349 C CD  . PRO   C 1 97  ? 24.21909  -59.46299 -48.24424 1.000 80.35000  ? 311 PRO   C CD  1 
ATOM   4350 N N   . GLY   C 1 98  ? 24.53668  -57.21583 -52.26854 1.000 82.88000  ? 312 GLY   C N   1 
ATOM   4351 C CA  . GLY   C 1 98  ? 23.76683  -57.19043 -53.50262 1.000 82.01000  ? 312 GLY   C CA  1 
ATOM   4352 C C   . GLY   C 1 98  ? 22.80489  -56.03138 -53.54940 1.000 78.83000  ? 312 GLY   C C   1 
ATOM   4353 O O   . GLY   C 1 98  ? 21.97100  -55.94708 -54.44248 1.000 80.64000  ? 312 GLY   C O   1 
ATOM   4354 N N   . ALA   C 1 99  ? 22.90581  -55.14166 -52.58113 1.000 76.02000  ? 313 ALA   C N   1 
ATOM   4355 C CA  . ALA   C 1 99  ? 22.11787  -53.93762 -52.60787 1.000 67.59000  ? 313 ALA   C CA  1 
ATOM   4356 C C   . ALA   C 1 99  ? 22.51305  -53.07829 -53.78857 1.000 63.56000  ? 313 ALA   C C   1 
ATOM   4357 O O   . ALA   C 1 99  ? 23.65810  -53.09322 -54.19844 1.000 57.56000  ? 313 ALA   C O   1 
ATOM   4358 C CB  . ALA   C 1 99  ? 22.35575  -53.18100 -51.33662 1.000 62.55000  ? 313 ALA   C CB  1 
ATOM   4359 N N   . PHE   C 1 100 ? 21.55816  -52.37607 -54.38248 1.000 58.70000  ? 314 PHE   C N   1 
ATOM   4360 C CA  . PHE   C 1 100 ? 21.85533  -51.46876 -55.48718 1.000 55.43000  ? 314 PHE   C CA  1 
ATOM   4361 C C   . PHE   C 1 100 ? 21.71136  -50.00986 -55.12177 1.000 49.91000  ? 314 PHE   C C   1 
ATOM   4362 O O   . PHE   C 1 100 ? 20.74630  -49.63400 -54.50077 1.000 49.66000  ? 314 PHE   C O   1 
ATOM   4363 C CB  . PHE   C 1 100 ? 20.94346  -51.77837 -56.67638 1.000 52.72000  ? 314 PHE   C CB  1 
ATOM   4364 C CG  . PHE   C 1 100 ? 21.06164  -50.81304 -57.81808 1.000 49.72000  ? 314 PHE   C CG  1 
ATOM   4365 C CD1 . PHE   C 1 100 ? 22.09975  -50.91183 -58.72299 1.000 53.79000  ? 314 PHE   C CD1 1 
ATOM   4366 C CD2 . PHE   C 1 100 ? 20.10971  -49.82994 -58.00691 1.000 46.70000  ? 314 PHE   C CD2 1 
ATOM   4367 C CE1 . PHE   C 1 100 ? 22.20091  -50.03452 -59.78172 1.000 45.00000  ? 314 PHE   C CE1 1 
ATOM   4368 C CE2 . PHE   C 1 100 ? 20.20488  -48.95064 -59.06264 1.000 46.74000  ? 314 PHE   C CE2 1 
ATOM   4369 C CZ  . PHE   C 1 100 ? 21.25298  -49.05043 -59.95054 1.000 48.14000  ? 314 PHE   C CZ  1 
ATOM   4370 N N   . TYR   C 1 101 ? 22.67744  -49.19180 -55.50341 1.000 45.64000  ? 315 TYR   C N   1 
ATOM   4371 C CA  . TYR   C 1 101 ? 22.58648  -47.75186 -55.27700 1.000 46.30000  ? 315 TYR   C CA  1 
ATOM   4372 C C   . TYR   C 1 101 ? 22.42067  -47.06946 -56.62082 1.000 50.81000  ? 315 TYR   C C   1 
ATOM   4373 O O   . TYR   C 1 101 ? 23.17877  -47.34522 -57.55981 1.000 52.32000  ? 315 TYR   C O   1 
ATOM   4374 C CB  . TYR   C 1 101 ? 23.83042  -47.20812 -54.56669 1.000 48.58000  ? 315 TYR   C CB  1 
ATOM   4375 C CG  . TYR   C 1 101 ? 24.00322  -47.78654 -53.17684 1.000 53.24000  ? 315 TYR   C CG  1 
ATOM   4376 C CD1 . TYR   C 1 101 ? 24.58115  -49.03562 -53.00414 1.000 53.18000  ? 315 TYR   C CD1 1 
ATOM   4377 C CD2 . TYR   C 1 101 ? 23.57612  -47.10485 -52.04769 1.000 47.81000  ? 315 TYR   C CD2 1 
ATOM   4378 C CE1 . TYR   C 1 101 ? 24.73897  -49.57998 -51.78028 1.000 53.62000  ? 315 TYR   C CE1 1 
ATOM   4379 C CE2 . TYR   C 1 101 ? 23.73594  -47.65122 -50.80183 1.000 52.71000  ? 315 TYR   C CE2 1 
ATOM   4380 C CZ  . TYR   C 1 101 ? 24.32187  -48.89829 -50.67313 1.000 57.93000  ? 315 TYR   C CZ  1 
ATOM   4381 O OH  . TYR   C 1 101 ? 24.50770  -49.48766 -49.44328 1.000 57.58000  ? 315 TYR   C OH  1 
ATOM   4382 N N   . GLY   C 1 102 ? 21.42272  -46.20638 -56.72669 1.000 50.77000  ? 316 GLY   C N   1 
ATOM   4383 C CA  . GLY   C 1 102 ? 21.05190  -45.68398 -58.02758 1.000 48.25000  ? 316 GLY   C CA  1 
ATOM   4384 C C   . GLY   C 1 102 ? 20.41596  -44.31598 -57.92826 1.000 51.60000  ? 316 GLY   C C   1 
ATOM   4385 O O   . GLY   C 1 102 ? 19.94885  -43.88927 -56.86419 1.000 52.21000  ? 316 GLY   C O   1 
ATOM   4386 N N   . VAL   C 1 103 ? 20.42012  -43.61865 -59.05505 1.000 47.13000  ? 317 VAL   C N   1 
ATOM   4387 C CA  . VAL   C 1 103 ? 19.73719  -42.34559 -59.15976 1.000 48.80000  ? 317 VAL   C CA  1 
ATOM   4388 C C   . VAL   C 1 103 ? 18.78433  -42.42420 -60.34090 1.000 50.18000  ? 317 VAL   C C   1 
ATOM   4389 O O   . VAL   C 1 103 ? 19.08142  -43.07192 -61.35005 1.000 56.53000  ? 317 VAL   C O   1 
ATOM   4390 C CB  . VAL   C 1 103 ? 20.73026  -41.17260 -59.28030 1.000 47.35000  ? 317 VAL   C CB  1 
ATOM   4391 C CG1 . VAL   C 1 103 ? 20.02437  -39.89744 -59.71401 1.000 49.35000  ? 317 VAL   C CG1 1 
ATOM   4392 C CG2 . VAL   C 1 103 ? 21.44011  -40.97002 -57.94115 1.000 48.01000  ? 317 VAL   C CG2 1 
ATOM   4393 N N   . SER   C 1 104 ? 17.61434  -41.82519 -60.17486 1.000 55.17000  ? 318 SER   C N   1 
ATOM   4394 C CA  . SER   C 1 104 ? 16.58747  -41.75285 -61.19697 1.000 53.20000  ? 318 SER   C CA  1 
ATOM   4395 C C   . SER   C 1 104 ? 16.16355  -40.30178 -61.36459 1.000 57.31000  ? 318 SER   C C   1 
ATOM   4396 O O   . SER   C 1 104 ? 15.91947  -39.59706 -60.37541 1.000 54.78000  ? 318 SER   C O   1 
ATOM   4397 C CB  . SER   C 1 104 ? 15.38338  -42.61090 -60.82036 1.000 53.70000  ? 318 SER   C CB  1 
ATOM   4398 O OG  . SER   C 1 104 ? 15.58237  -43.95479 -61.22373 1.000 62.08000  ? 318 SER   C OG  1 
ATOM   4399 N N   . SER   C 1 105 ? 16.08672  -39.86041 -62.62147 1.000 54.13000  ? 319 SER   C N   1 
ATOM   4400 C CA  . SER   C 1 105 ? 15.66883  -38.50629 -62.94612 1.000 56.61000  ? 319 SER   C CA  1 
ATOM   4401 C C   . SER   C 1 105 ? 14.78397  -38.51389 -64.18823 1.000 59.16000  ? 319 SER   C C   1 
ATOM   4402 O O   . SER   C 1 105 ? 14.96005  -39.32863 -65.09945 1.000 56.92000  ? 319 SER   C O   1 
ATOM   4403 C CB  . SER   C 1 105 ? 16.87190  -37.59528 -63.18371 1.000 52.20000  ? 319 SER   C CB  1 
ATOM   4404 O OG  . SER   C 1 105 ? 17.57001  -38.04598 -64.32876 1.000 56.03000  ? 319 SER   C OG  1 
ATOM   4405 N N   . GLN   C 1 106 ? 13.81502  -37.59584 -64.20308 1.000 58.51000  ? 320 GLN   C N   1 
ATOM   4406 C CA  . GLN   C 1 106 ? 12.94317  -37.38346 -65.35012 1.000 56.70000  ? 320 GLN   C CA  1 
ATOM   4407 C C   . GLN   C 1 106 ? 12.73226  -35.89838 -65.58471 1.000 57.28000  ? 320 GLN   C C   1 
ATOM   4408 O O   . GLN   C 1 106 ? 12.66118  -35.11066 -64.63149 1.000 54.13000  ? 320 GLN   C O   1 
ATOM   4409 C CB  . GLN   C 1 106 ? 11.59511  -38.05546 -65.16548 1.000 56.94000  ? 320 GLN   C CB  1 
ATOM   4410 C CG  . GLN   C 1 106 ? 11.69797  -39.37566 -64.47486 1.000 61.59000  ? 320 GLN   C CG  1 
ATOM   4411 C CD  . GLN   C 1 106 ? 10.97501  -40.46441 -65.22026 1.000 69.64000  ? 320 GLN   C CD  1 
ATOM   4412 O OE1 . GLN   C 1 106 ? 9.85608   -40.25922 -65.71334 1.000 74.88000  ? 320 GLN   C OE1 1 
ATOM   4413 N NE2 . GLN   C 1 106 ? 11.62897  -41.61640 -65.36252 1.000 67.70000  ? 320 GLN   C NE2 1 
ATOM   4414 N N   . TYR   C 1 107 ? 12.61543  -35.53701 -66.86262 1.000 52.03000  ? 321 TYR   C N   1 
ATOM   4415 C CA  . TYR   C 1 107 ? 12.38755  -34.15987 -67.27925 1.000 56.35000  ? 321 TYR   C CA  1 
ATOM   4416 C C   . TYR   C 1 107 ? 11.45069  -34.12448 -68.48335 1.000 58.20000  ? 321 TYR   C C   1 
ATOM   4417 O O   . TYR   C 1 107 ? 11.39374  -35.07324 -69.27363 1.000 57.78000  ? 321 TYR   C O   1 
ATOM   4418 C CB  . TYR   C 1 107 ? 13.69462  -33.47782 -67.65789 1.000 53.06000  ? 321 TYR   C CB  1 
ATOM   4419 C CG  . TYR   C 1 107 ? 14.84750  -33.69516 -66.69781 1.000 57.06000  ? 321 TYR   C CG  1 
ATOM   4420 C CD1 . TYR   C 1 107 ? 15.56545  -34.88318 -66.72308 1.000 56.55000  ? 321 TYR   C CD1 1 
ATOM   4421 C CD2 . TYR   C 1 107 ? 15.27544  -32.68343 -65.83547 1.000 54.68000  ? 321 TYR   C CD2 1 
ATOM   4422 C CE1 . TYR   C 1 107 ? 16.62434  -35.09047 -65.89201 1.000 59.92000  ? 321 TYR   C CE1 1 
ATOM   4423 C CE2 . TYR   C 1 107 ? 16.34933  -32.87672 -64.99439 1.000 56.94000  ? 321 TYR   C CE2 1 
ATOM   4424 C CZ  . TYR   C 1 107 ? 17.02328  -34.09474 -65.02967 1.000 64.06000  ? 321 TYR   C CZ  1 
ATOM   4425 O OH  . TYR   C 1 107 ? 18.11517  -34.35803 -64.21962 1.000 64.18000  ? 321 TYR   C OH  1 
ATOM   4426 N N   . SER   C 1 108 ? 10.73976  -33.00340 -68.65011 1.000 57.38000  ? 322 SER   C N   1 
ATOM   4427 C CA  . SER   C 1 108 ? 9.79991   -32.83703 -69.75517 1.000 53.92000  ? 322 SER   C CA  1 
ATOM   4428 C C   . SER   C 1 108 ? 9.99505   -31.47884 -70.41975 1.000 55.61000  ? 322 SER   C C   1 
ATOM   4429 O O   . SER   C 1 108 ? 10.46201  -30.53205 -69.77842 1.000 56.09000  ? 322 SER   C O   1 
ATOM   4430 C CB  . SER   C 1 108 ? 8.35284   -32.98310 -69.26839 1.000 48.34000  ? 322 SER   C CB  1 
ATOM   4431 O OG  . SER   C 1 108 ? 7.93281   -31.82029 -68.57410 1.000 49.58000  ? 322 SER   C OG  1 
ATOM   4432 N N   . SER   C 1 109 ? 9.64521   -31.38745 -71.71376 1.000 51.86000  ? 323 SER   C N   1 
ATOM   4433 C CA  . SER   C 1 109 ? 9.57835   -30.10124 -72.41040 1.000 53.69000  ? 323 SER   C CA  1 
ATOM   4434 C C   . SER   C 1 109 ? 8.54948   -30.16586 -73.53954 1.000 59.76000  ? 323 SER   C C   1 
ATOM   4435 O O   . SER   C 1 109 ? 8.07848   -31.23973 -73.92091 1.000 58.55000  ? 323 SER   C O   1 
ATOM   4436 C CB  . SER   C 1 109 ? 10.93744  -29.67613 -72.98311 1.000 48.62000  ? 323 SER   C CB  1 
ATOM   4437 O OG  . SER   C 1 109 ? 11.32454  -30.47083 -74.09029 1.000 50.95000  ? 323 SER   C OG  1 
ATOM   4438 N N   . ALA   C 1 110 ? 8.21160   -28.99168 -74.09023 1.000 58.35000  ? 324 ALA   C N   1 
ATOM   4439 C CA  . ALA   C 1 110 ? 7.34575   -28.94630 -75.26633 1.000 53.37000  ? 324 ALA   C CA  1 
ATOM   4440 C C   . ALA   C 1 110 ? 8.12589   -29.18796 -76.54730 1.000 53.57000  ? 324 ALA   C C   1 
ATOM   4441 O O   . ALA   C 1 110 ? 7.54799   -29.61264 -77.55350 1.000 61.73000  ? 324 ALA   C O   1 
ATOM   4442 C CB  . ALA   C 1 110 ? 6.61682   -27.60225 -75.33402 1.000 55.09000  ? 324 ALA   C CB  1 
ATOM   4443 N N   . ASP   C 1 111 ? 9.42390   -28.93703 -76.50807 1.000 54.85000  ? 325 ASP   C N   1 
ATOM   4444 C CA  . ASP   C 1 111 ? 10.37302  -29.14776 -77.58202 1.000 54.04000  ? 325 ASP   C CA  1 
ATOM   4445 C C   . ASP   C 1 111 ? 11.03594  -30.51482 -77.49734 1.000 62.34000  ? 325 ASP   C C   1 
ATOM   4446 O O   . ASP   C 1 111 ? 10.99979  -31.19911 -76.47455 1.000 64.20000  ? 325 ASP   C O   1 
ATOM   4447 C CB  . ASP   C 1 111 ? 11.47806  -28.10183 -77.53658 1.000 61.26000  ? 325 ASP   C CB  1 
ATOM   4448 C CG  . ASP   C 1 111 ? 11.02218  -26.78066 -78.02625 1.000 74.69000  ? 325 ASP   C CG  1 
ATOM   4449 O OD1 . ASP   C 1 111 ? 10.71133  -26.68629 -79.23826 1.000 81.12000  ? 325 ASP   C OD1 1 
ATOM   4450 O OD2 . ASP   C 1 111 ? 11.04012  -25.82490 -77.21497 1.000 82.51000  ? 325 ASP   C OD2 1 
ATOM   4451 N N   . SER   C 1 112 ? 11.71406  -30.86553 -78.58436 1.000 71.55000  ? 326 SER   C N   1 
ATOM   4452 C CA  . SER   C 1 112 ? 12.45402  -32.11152 -78.72664 1.000 66.58000  ? 326 SER   C CA  1 
ATOM   4453 C C   . SER   C 1 112 ? 13.89008  -31.74949 -79.07236 1.000 68.70000  ? 326 SER   C C   1 
ATOM   4454 O O   . SER   C 1 112 ? 14.15023  -31.10920 -80.09914 1.000 80.05000  ? 326 SER   C O   1 
ATOM   4455 C CB  . SER   C 1 112 ? 11.81311  -32.98617 -79.81397 1.000 62.14000  ? 326 SER   C CB  1 
ATOM   4456 O OG  . SER   C 1 112 ? 12.70712  -33.96107 -80.30315 1.000 58.98000  ? 326 SER   C OG  1 
ATOM   4457 N N   . MET   C 1 113 ? 14.81595  -32.14378 -78.21336 1.000 60.01000  ? 327 MET   C N   1 
ATOM   4458 C CA  . MET   C 1 113 ? 16.20698  -31.73382 -78.31008 1.000 59.88000  ? 327 MET   C CA  1 
ATOM   4459 C C   . MET   C 1 113 ? 16.98084  -32.71410 -77.46727 1.000 60.98000  ? 327 MET   C C   1 
ATOM   4460 O O   . MET   C 1 113 ? 16.50269  -33.12639 -76.41045 1.000 68.65000  ? 327 MET   C O   1 
ATOM   4461 C CB  . MET   C 1 113 ? 16.44198  -30.34300 -77.73464 1.000 59.23000  ? 327 MET   C CB  1 
ATOM   4462 C CG  . MET   C 1 113 ? 15.55584  -30.14231 -76.51469 1.000 64.29000  ? 327 MET   C CG  1 
ATOM   4463 S SD  . MET   C 1 113 ? 15.30585  -28.45946 -75.96923 1.000 65.35000  ? 327 MET   C SD  1 
ATOM   4464 C CE  . MET   C 1 113 ? 14.69464  -28.72492 -74.29938 1.000 58.02000  ? 327 MET   C CE  1 
ATOM   4465 N N   . THR   C 1 114 ? 18.16787  -33.07003 -77.90323 1.000 57.59000  ? 328 THR   C N   1 
ATOM   4466 C CA  . THR   C 1 114 ? 18.98573  -33.90631 -77.05138 1.000 61.81000  ? 328 THR   C CA  1 
ATOM   4467 C C   . THR   C 1 114 ? 19.60864  -33.05566 -75.95205 1.000 63.84000  ? 328 THR   C C   1 
ATOM   4468 O O   . THR   C 1 114 ? 20.18972  -31.99861 -76.21868 1.000 69.76000  ? 328 THR   C O   1 
ATOM   4469 C CB  . THR   C 1 114 ? 20.03680  -34.61312 -77.88546 1.000 62.47000  ? 328 THR   C CB  1 
ATOM   4470 O OG1 . THR   C 1 114 ? 19.45394  -34.93172 -79.15662 1.000 76.04000  ? 328 THR   C OG1 1 
ATOM   4471 C CG2 . THR   C 1 114 ? 20.44966  -35.89134 -77.20578 1.000 62.53000  ? 328 THR   C CG2 1 
ATOM   4472 N N   . ILE   C 1 115 ? 19.45547  -33.50402 -74.71220 1.000 57.49000  ? 329 ILE   C N   1 
ATOM   4473 C CA  . ILE   C 1 115 ? 19.94836  -32.78739 -73.53894 1.000 60.43000  ? 329 ILE   C CA  1 
ATOM   4474 C C   . ILE   C 1 115 ? 21.21127  -33.46460 -73.01898 1.000 56.03000  ? 329 ILE   C C   1 
ATOM   4475 O O   . ILE   C 1 115 ? 21.39523  -34.68357 -73.13532 1.000 56.30000  ? 329 ILE   C O   1 
ATOM   4476 C CB  . ILE   C 1 115 ? 18.85424  -32.67666 -72.44903 1.000 53.56000  ? 329 ILE   C CB  1 
ATOM   4477 C CG1 . ILE   C 1 115 ? 18.49810  -34.03782 -71.84048 1.000 47.85000  ? 329 ILE   C CG1 1 
ATOM   4478 C CG2 . ILE   C 1 115 ? 17.60834  -32.02043 -73.01899 1.000 58.15000  ? 329 ILE   C CG2 1 
ATOM   4479 C CD1 . ILE   C 1 115 ? 17.70595  -33.92915 -70.57154 1.000 46.86000  ? 329 ILE   C CD1 1 
ATOM   4480 N N   . SER   C 1 116 ? 22.11224  -32.64379 -72.48663 1.000 52.81000  ? 330 SER   C N   1 
ATOM   4481 C CA  . SER   C 1 116 ? 23.29514  -33.10006 -71.77062 1.000 54.39000  ? 330 SER   C CA  1 
ATOM   4482 C C   . SER   C 1 116 ? 23.10397  -32.78948 -70.28856 1.000 52.22000  ? 330 SER   C C   1 
ATOM   4483 O O   . SER   C 1 116 ? 22.98398  -31.62159 -69.90723 1.000 49.06000  ? 330 SER   C O   1 
ATOM   4484 C CB  . SER   C 1 116 ? 24.55723  -32.42496 -72.31328 1.000 57.60000  ? 330 SER   C CB  1 
ATOM   4485 O OG  . SER   C 1 116 ? 25.71616  -33.16911 -71.96935 1.000 61.81000  ? 330 SER   C OG  1 
ATOM   4486 N N   . VAL   C 1 117 ? 23.07682  -33.82872 -69.46086 1.000 50.66000  ? 331 VAL   C N   1 
ATOM   4487 C CA  . VAL   C 1 117 ? 22.90866  -33.68014 -68.01984 1.000 55.17000  ? 331 VAL   C CA  1 
ATOM   4488 C C   . VAL   C 1 117 ? 24.25757  -33.88240 -67.34374 1.000 50.30000  ? 331 VAL   C C   1 
ATOM   4489 O O   . VAL   C 1 117 ? 24.75351  -35.01244 -67.27901 1.000 46.86000  ? 331 VAL   C O   1 
ATOM   4490 C CB  . VAL   C 1 117 ? 21.86854  -34.65326 -67.45225 1.000 53.11000  ? 331 VAL   C CB  1 
ATOM   4491 C CG1 . VAL   C 1 117 ? 21.69738  -34.39669 -65.95720 1.000 53.91000  ? 331 VAL   C CG1 1 
ATOM   4492 C CG2 . VAL   C 1 117 ? 20.53464  -34.51098 -68.19237 1.000 50.24000  ? 331 VAL   C CG2 1 
ATOM   4493 N N   . SER   C 1 118 ? 24.82455  -32.79058 -66.81435 1.000 48.29000  ? 332 SER   C N   1 
ATOM   4494 C CA  . SER   C 1 118 ? 26.05346  -32.81587 -66.01721 1.000 52.41000  ? 332 SER   C CA  1 
ATOM   4495 C C   . SER   C 1 118 ? 25.72328  -32.76229 -64.52723 1.000 50.73000  ? 332 SER   C C   1 
ATOM   4496 O O   . SER   C 1 118 ? 25.11027  -31.79640 -64.04902 1.000 47.31000  ? 332 SER   C O   1 
ATOM   4497 C CB  . SER   C 1 118 ? 26.98055  -31.64881 -66.38076 1.000 50.95000  ? 332 SER   C CB  1 
ATOM   4498 O OG  . SER   C 1 118 ? 28.04345  -31.50813 -65.43159 1.000 55.87000  ? 332 SER   C OG  1 
ATOM   4499 N N   . THR   C 1 119 ? 26.16015  -33.78353 -63.79948 1.000 53.27000  ? 333 THR   C N   1 
ATOM   4500 C CA  . THR   C 1 119 ? 26.12197  -33.80695 -62.34249 1.000 49.39000  ? 333 THR   C CA  1 
ATOM   4501 C C   . THR   C 1 119 ? 27.52892  -33.52516 -61.83724 1.000 48.53000  ? 333 THR   C C   1 
ATOM   4502 O O   . THR   C 1 119 ? 28.49396  -34.09906 -62.34929 1.000 52.54000  ? 333 THR   C O   1 
ATOM   4503 C CB  . THR   C 1 119 ? 25.62385  -35.16707 -61.84895 1.000 49.14000  ? 333 THR   C CB  1 
ATOM   4504 O OG1 . THR   C 1 119 ? 24.29390  -35.39487 -62.34718 1.000 54.00000  ? 333 THR   C OG1 1 
ATOM   4505 C CG2 . THR   C 1 119 ? 25.60566  -35.20752 -60.32596 1.000 48.17000  ? 333 THR   C CG2 1 
ATOM   4506 N N   . LYS   C 1 120 ? 27.67085  -32.62645 -60.87196 1.000 45.94000  ? 334 LYS   C N   1 
ATOM   4507 C CA  . LYS   C 1 120 ? 29.00480  -32.31367 -60.34971 1.000 51.33000  ? 334 LYS   C CA  1 
ATOM   4508 C C   . LYS   C 1 120 ? 29.00661  -32.42611 -58.83374 1.000 51.32000  ? 334 LYS   C C   1 
ATOM   4509 O O   . LYS   C 1 120 ? 28.43657  -31.57329 -58.13756 1.000 51.48000  ? 334 LYS   C O   1 
ATOM   4510 C CB  . LYS   C 1 120 ? 29.46592  -30.92956 -60.79125 1.000 56.25000  ? 334 LYS   C CB  1 
ATOM   4511 C CG  . LYS   C 1 120 ? 29.80910  -30.84114 -62.28718 1.000 62.61000  ? 334 LYS   C CG  1 
ATOM   4512 C CD  . LYS   C 1 120 ? 30.51419  -29.53408 -62.58071 1.000 64.55000  ? 334 LYS   C CD  1 
ATOM   4513 C CE  . LYS   C 1 120 ? 30.95537  -29.41768 -64.01762 1.000 67.62000  ? 334 LYS   C CE  1 
ATOM   4514 N NZ  . LYS   C 1 120 ? 31.80445  -28.20567 -64.19617 1.000 74.55000  ? 334 LYS   C NZ  1 
ATOM   4515 N N   . VAL   C 1 121 ? 29.64250  -33.47429 -58.32697 1.000 50.21000  ? 335 VAL   C N   1 
ATOM   4516 C CA  . VAL   C 1 121 ? 29.70132  -33.72171 -56.89204 1.000 53.97000  ? 335 VAL   C CA  1 
ATOM   4517 C C   . VAL   C 1 121 ? 30.87829  -32.94393 -56.31867 1.000 51.52000  ? 335 VAL   C C   1 
ATOM   4518 O O   . VAL   C 1 121 ? 32.03531  -33.24490 -56.60962 1.000 56.84000  ? 335 VAL   C O   1 
ATOM   4519 C CB  . VAL   C 1 121 ? 29.82121  -35.21481 -56.58246 1.000 53.62000  ? 335 VAL   C CB  1 
ATOM   4520 C CG1 . VAL   C 1 121 ? 29.54102  -35.45723 -55.10756 1.000 52.56000  ? 335 VAL   C CG1 1 
ATOM   4521 C CG2 . VAL   C 1 121 ? 28.85428  -35.99851 -57.46080 1.000 54.00000  ? 335 VAL   C CG2 1 
ATOM   4522 N N   . CYS   C 1 122 ? 30.58024  -31.92915 -55.53040 1.000 46.49000  ? 336 CYS   C N   1 
ATOM   4523 C CA  . CYS   C 1 122 ? 31.59219  -31.13539 -54.86405 1.000 55.11000  ? 336 CYS   C CA  1 
ATOM   4524 C C   . CYS   C 1 122 ? 31.67900  -31.57182 -53.41117 1.000 59.95000  ? 336 CYS   C C   1 
ATOM   4525 O O   . CYS   C 1 122 ? 30.70291  -31.46100 -52.65725 1.000 53.30000  ? 336 CYS   C O   1 
ATOM   4526 C CB  . CYS   C 1 122 ? 31.27027  -29.65435 -54.96866 1.000 53.48000  ? 336 CYS   C CB  1 
ATOM   4527 S SG  . CYS   C 1 122 ? 31.34950  -29.19585 -56.66851 1.000 77.21000  ? 336 CYS   C SG  1 
ATOM   4528 N N   . SER   C 1 123 ? 32.84593  -32.07499 -53.02717 1.000 66.56000  ? 337 SER   C N   1 
ATOM   4529 C CA  . SER   C 1 123 ? 33.09075  -32.53040 -51.66728 1.000 62.48000  ? 337 SER   C CA  1 
ATOM   4530 C C   . SER   C 1 123 ? 34.41172  -31.96559 -51.21095 1.000 62.58000  ? 337 SER   C C   1 
ATOM   4531 O O   . SER   C 1 123 ? 35.44578  -32.20945 -51.85090 1.000 66.42000  ? 337 SER   C O   1 
ATOM   4532 C CB  . SER   C 1 123 ? 33.12067  -34.04842 -51.59072 1.000 57.73000  ? 337 SER   C CB  1 
ATOM   4533 O OG  . SER   C 1 123 ? 33.18049  -34.44182 -50.23983 1.000 54.39000  ? 337 SER   C OG  1 
ATOM   4534 N N   . PHE   C 1 124 ? 34.36862  -31.17891 -50.13773 1.000 57.16000  ? 338 PHE   C N   1 
ATOM   4535 C CA  . PHE   C 1 124 ? 35.58156  -30.71316 -49.46345 1.000 63.57000  ? 338 PHE   C CA  1 
ATOM   4536 C C   . PHE   C 1 124 ? 36.53571  -30.01792 -50.43713 1.000 66.26000  ? 338 PHE   C C   1 
ATOM   4537 O O   . PHE   C 1 124 ? 37.74670  -30.26197 -50.44105 1.000 62.21000  ? 338 PHE   C O   1 
ATOM   4538 C CB  . PHE   C 1 124 ? 36.25242  -31.87341 -48.72371 1.000 57.24000  ? 338 PHE   C CB  1 
ATOM   4539 C CG  . PHE   C 1 124 ? 35.43226  -32.38971 -47.56496 1.000 62.16000  ? 338 PHE   C CG  1 
ATOM   4540 C CD1 . PHE   C 1 124 ? 35.30615  -31.63604 -46.39675 1.000 62.07000  ? 338 PHE   C CD1 1 
ATOM   4541 C CD2 . PHE   C 1 124 ? 34.75721  -33.59965 -47.64639 1.000 63.45000  ? 338 PHE   C CD2 1 
ATOM   4542 C CE1 . PHE   C 1 124 ? 34.54900  -32.09132 -45.33097 1.000 60.61000  ? 338 PHE   C CE1 1 
ATOM   4543 C CE2 . PHE   C 1 124 ? 33.98506  -34.05193 -46.57462 1.000 63.77000  ? 338 PHE   C CE2 1 
ATOM   4544 C CZ  . PHE   C 1 124 ? 33.87796  -33.28126 -45.42240 1.000 59.50000  ? 338 PHE   C CZ  1 
ATOM   4545 N N   . GLY   C 1 125 ? 35.97985  -29.13165 -51.26294 1.000 66.65000  ? 339 GLY   C N   1 
ATOM   4546 C CA  . GLY   C 1 125 ? 36.77600  -28.34542 -52.17461 1.000 62.07000  ? 339 GLY   C CA  1 
ATOM   4547 C C   . GLY   C 1 125 ? 37.27511  -29.08509 -53.38477 1.000 64.34000  ? 339 GLY   C C   1 
ATOM   4548 O O   . GLY   C 1 125 ? 38.08722  -28.53691 -54.13051 1.000 67.84000  ? 339 GLY   C O   1 
ATOM   4549 N N   . LYS   C 1 126 ? 36.81308  -30.30500 -53.62118 1.000 70.71000  ? 340 LYS   C N   1 
ATOM   4550 C CA  . LYS   C 1 126 ? 37.18819  -31.02666 -54.82535 1.000 70.48000  ? 340 LYS   C CA  1 
ATOM   4551 C C   . LYS   C 1 126 ? 35.95326  -31.53939 -55.56864 1.000 72.52000  ? 340 LYS   C C   1 
ATOM   4552 O O   . LYS   C 1 126 ? 34.97716  -32.00552 -54.95490 1.000 65.45000  ? 340 LYS   C O   1 
ATOM   4553 C CB  . LYS   C 1 126 ? 38.14810  -32.17580 -54.49257 1.000 64.61000  ? 340 LYS   C CB  1 
ATOM   4554 C CG  . LYS   C 1 126 ? 39.60711  -31.73689 -54.43926 1.000 68.57000  ? 340 LYS   C CG  1 
ATOM   4555 C CD  . LYS   C 1 126 ? 40.44920  -32.50462 -55.47239 1.000 80.08000  ? 340 LYS   C CD  1 
ATOM   4556 C CE  . LYS   C 1 126 ? 40.31240  -31.88321 -56.85722 1.000 81.78000  ? 340 LYS   C CE  1 
ATOM   4557 N NZ  . LYS   C 1 126 ? 40.82948  -32.78792 -57.91642 1.000 91.15000  ? 340 LYS   C NZ  1 
ATOM   4558 N N   . GLN   C 1 127 ? 35.99943  -31.41100 -56.89960 1.000 70.10000  ? 341 GLN   C N   1 
ATOM   4559 C CA  . GLN   C 1 127 ? 35.08650  -32.09869 -57.80791 1.000 65.74000  ? 341 GLN   C CA  1 
ATOM   4560 C C   . GLN   C 1 127 ? 35.46243  -33.56972 -57.77830 1.000 61.92000  ? 341 GLN   C C   1 
ATOM   4561 O O   . GLN   C 1 127 ? 36.29150  -34.04253 -58.55134 1.000 70.19000  ? 341 GLN   C O   1 
ATOM   4562 C CB  . GLN   C 1 127 ? 35.17470  -31.55128 -59.22874 1.000 67.41000  ? 341 GLN   C CB  1 
ATOM   4563 C CG  . GLN   C 1 127 ? 34.53479  -30.19317 -59.48742 1.000 68.25000  ? 341 GLN   C CG  1 
ATOM   4564 C CD  . GLN   C 1 127 ? 33.97097  -30.07973 -60.92146 1.000 72.46000  ? 341 GLN   C CD  1 
ATOM   4565 O OE1 . GLN   C 1 127 ? 33.42706  -29.04259 -61.30222 1.000 77.66000  ? 341 GLN   C OE1 1 
ATOM   4566 N NE2 . GLN   C 1 127 ? 34.06301  -31.16550 -61.69676 1.000 63.43000  ? 341 GLN   C NE2 1 
ATOM   4567 N N   . VAL   C 1 128 ? 34.84729  -34.30696 -56.86259 1.000 62.56000  ? 342 VAL   C N   1 
ATOM   4568 C CA  . VAL   C 1 128 ? 35.16521  -35.72101 -56.72096 1.000 63.60000  ? 342 VAL   C CA  1 
ATOM   4569 C C   . VAL   C 1 128 ? 34.64631  -36.50564 -57.91826 1.000 64.45000  ? 342 VAL   C C   1 
ATOM   4570 O O   . VAL   C 1 128 ? 35.23332  -37.51755 -58.31848 1.000 71.35000  ? 342 VAL   C O   1 
ATOM   4571 C CB  . VAL   C 1 128 ? 34.58302  -36.24938 -55.39519 1.000 67.17000  ? 342 VAL   C CB  1 
ATOM   4572 C CG1 . VAL   C 1 128 ? 35.15692  -35.46175 -54.21789 1.000 59.10000  ? 342 VAL   C CG1 1 
ATOM   4573 C CG2 . VAL   C 1 128 ? 33.06003  -36.18330 -55.40235 1.000 60.06000  ? 342 VAL   C CG2 1 
ATOM   4574 N N   . VAL   C 1 129 ? 33.53340  -36.06242 -58.50726 1.000 65.69000  ? 343 VAL   C N   1 
ATOM   4575 C CA  . VAL   C 1 129 ? 32.86150  -36.76406 -59.59755 1.000 67.28000  ? 343 VAL   C CA  1 
ATOM   4576 C C   . VAL   C 1 129 ? 32.26367  -35.74475 -60.56932 1.000 63.90000  ? 343 VAL   C C   1 
ATOM   4577 O O   . VAL   C 1 129 ? 31.57466  -34.80284 -60.15813 1.000 61.52000  ? 343 VAL   C O   1 
ATOM   4578 C CB  . VAL   C 1 129 ? 31.75640  -37.72416 -59.08396 1.000 67.04000  ? 343 VAL   C CB  1 
ATOM   4579 C CG1 . VAL   C 1 129 ? 31.25749  -38.60681 -60.20228 1.000 65.30000  ? 343 VAL   C CG1 1 
ATOM   4580 C CG2 . VAL   C 1 129 ? 32.27722  -38.63552 -57.95917 1.000 64.18000  ? 343 VAL   C CG2 1 
ATOM   4581 N N   . GLU   C 1 130 ? 32.52781  -35.93039 -61.85734 1.000 60.90000  ? 344 GLU   C N   1 
ATOM   4582 C CA  . GLU   C 1 130 ? 31.70397  -35.35804 -62.90427 1.000 57.84000  ? 344 GLU   C CA  1 
ATOM   4583 C C   . GLU   C 1 130 ? 31.14501  -36.52879 -63.68868 1.000 57.05000  ? 344 GLU   C C   1 
ATOM   4584 O O   . GLU   C 1 130 ? 31.84999  -37.51275 -63.91189 1.000 62.44000  ? 344 GLU   C O   1 
ATOM   4585 C CB  . GLU   C 1 130 ? 32.47612  -34.40581 -63.82090 1.000 60.28000  ? 344 GLU   C CB  1 
ATOM   4586 C CG  . GLU   C 1 130 ? 31.57126  -33.43954 -64.61173 1.000 64.43000  ? 344 GLU   C CG  1 
ATOM   4587 C CD  . GLU   C 1 130 ? 32.35241  -32.46031 -65.51435 1.000 72.88000  ? 344 GLU   C CD  1 
ATOM   4588 O OE1 . GLU   C 1 130 ? 33.59242  -32.63532 -65.67025 1.000 58.12000  ? 344 GLU   C OE1 1 
ATOM   4589 O OE2 . GLU   C 1 130 ? 31.71352  -31.53311 -66.08015 1.000 69.26000  ? 344 GLU   C OE2 1 
ATOM   4590 N N   . LYS   C 1 131 ? 29.86305  -36.45063 -64.03082 1.000 55.47000  ? 345 LYS   C N   1 
ATOM   4591 C CA  . LYS   C 1 131 ? 29.20310  -37.46236 -64.84919 1.000 58.15000  ? 345 LYS   C CA  1 
ATOM   4592 C C   . LYS   C 1 131 ? 28.28525  -36.74403 -65.83209 1.000 59.85000  ? 345 LYS   C C   1 
ATOM   4593 O O   . LYS   C 1 131 ? 27.41824  -35.96511 -65.41297 1.000 53.13000  ? 345 LYS   C O   1 
ATOM   4594 C CB  . LYS   C 1 131 ? 28.42095  -38.46157 -63.99158 1.000 53.09000  ? 345 LYS   C CB  1 
ATOM   4595 C CG  . LYS   C 1 131 ? 28.27697  -39.84738 -64.63400 1.000 59.96000  ? 345 LYS   C CG  1 
ATOM   4596 C CD  . LYS   C 1 131 ? 27.21384  -40.70454 -63.89938 1.000 73.66000  ? 345 LYS   C CD  1 
ATOM   4597 C CE  . LYS   C 1 131 ? 27.40379  -42.23251 -64.04181 1.000 68.16000  ? 345 LYS   C CE  1 
ATOM   4598 N NZ  . LYS   C 1 131 ? 28.21462  -42.85587 -62.93289 1.000 68.48000  ? 345 LYS   C NZ  1 
ATOM   4599 N N   . VAL   C 1 132 ? 28.49540  -36.98566 -67.13114 1.000 50.83000  ? 346 VAL   C N   1 
ATOM   4600 C CA  . VAL   C 1 132 ? 27.72156  -36.35531 -68.19505 1.000 53.60000  ? 346 VAL   C CA  1 
ATOM   4601 C C   . VAL   C 1 132 ? 26.91859  -37.42906 -68.92246 1.000 56.67000  ? 346 VAL   C C   1 
ATOM   4602 O O   . VAL   C 1 132 ? 27.48564  -38.28388 -69.61464 1.000 60.60000  ? 346 VAL   C O   1 
ATOM   4603 C CB  . VAL   C 1 132 ? 28.61171  -35.57307 -69.16671 1.000 49.42000  ? 346 VAL   C CB  1 
ATOM   4604 C CG1 . VAL   C 1 132 ? 27.85187  -35.25867 -70.39871 1.000 49.90000  ? 346 VAL   C CG1 1 
ATOM   4605 C CG2 . VAL   C 1 132 ? 29.06969  -34.27628 -68.51827 1.000 54.49000  ? 346 VAL   C CG2 1 
ATOM   4606 N N   . GLU   C 1 133 ? 25.59858  -37.36804 -68.77660 1.000 57.53000  ? 347 GLU   C N   1 
ATOM   4607 C CA  . GLU   C 1 133 ? 24.65862  -38.25980 -69.43797 1.000 54.88000  ? 347 GLU   C CA  1 
ATOM   4608 C C   . GLU   C 1 133 ? 24.02279  -37.49544 -70.59682 1.000 57.07000  ? 347 GLU   C C   1 
ATOM   4609 O O   . GLU   C 1 133 ? 23.66883  -36.32146 -70.44552 1.000 58.48000  ? 347 GLU   C O   1 
ATOM   4610 C CB  . GLU   C 1 133 ? 23.59847  -38.75005 -68.43624 1.000 55.28000  ? 347 GLU   C CB  1 
ATOM   4611 C CG  . GLU   C 1 133 ? 24.20929  -39.51143 -67.22839 1.000 61.11000  ? 347 GLU   C CG  1 
ATOM   4612 C CD  . GLU   C 1 133 ? 23.28614  -39.64775 -66.00354 1.000 64.15000  ? 347 GLU   C CD  1 
ATOM   4613 O OE1 . GLU   C 1 133 ? 22.88712  -38.61090 -65.41629 1.000 65.01000  ? 347 GLU   C OE1 1 
ATOM   4614 O OE2 . GLU   C 1 133 ? 22.98604  -40.79885 -65.60392 1.000 62.93000  ? 347 GLU   C OE2 1 
ATOM   4615 N N   . THR   C 1 134 ? 23.91590  -38.14109 -71.76003 1.000 56.95000  ? 348 THR   C N   1 
ATOM   4616 C CA  . THR   C 1 134 ? 23.14506  -37.61672 -72.88597 1.000 55.75000  ? 348 THR   C CA  1 
ATOM   4617 C C   . THR   C 1 134 ? 21.78603  -38.30766 -72.90633 1.000 55.41000  ? 348 THR   C C   1 
ATOM   4618 O O   . THR   C 1 134 ? 21.70696  -39.53369 -72.78970 1.000 57.41000  ? 348 THR   C O   1 
ATOM   4619 C CB  . THR   C 1 134 ? 23.87621  -37.82737 -74.22394 1.000 57.98000  ? 348 THR   C CB  1 
ATOM   4620 O OG1 . THR   C 1 134 ? 25.20123  -37.27644 -74.16862 1.000 58.70000  ? 348 THR   C OG1 1 
ATOM   4621 C CG2 . THR   C 1 134 ? 23.13938  -37.16500 -75.36083 1.000 61.53000  ? 348 THR   C CG2 1 
ATOM   4622 N N   . GLU   C 1 135 ? 20.71708  -37.53157 -73.03323 1.000 55.62000  ? 349 GLU   C N   1 
ATOM   4623 C CA  . GLU   C 1 135 ? 19.38405  -38.11452 -73.00956 1.000 63.07000  ? 349 GLU   C CA  1 
ATOM   4624 C C   . GLU   C 1 135 ? 18.54922  -37.65313 -74.20253 1.000 66.41000  ? 349 GLU   C C   1 
ATOM   4625 O O   . GLU   C 1 135 ? 18.56532  -36.47502 -74.57918 1.000 63.59000  ? 349 GLU   C O   1 
ATOM   4626 C CB  . GLU   C 1 135 ? 18.68291  -37.77987 -71.70255 1.000 60.52000  ? 349 GLU   C CB  1 
ATOM   4627 C CG  . GLU   C 1 135 ? 18.97973  -38.77821 -70.57881 1.000 64.37000  ? 349 GLU   C CG  1 
ATOM   4628 C CD  . GLU   C 1 135 ? 18.86071  -40.25608 -71.00925 1.000 72.98000  ? 349 GLU   C CD  1 
ATOM   4629 O OE1 . GLU   C 1 135 ? 17.99780  -40.59879 -71.87146 1.000 72.12000  ? 349 GLU   C OE1 1 
ATOM   4630 O OE2 . GLU   C 1 135 ? 19.62261  -41.08928 -70.44841 1.000 76.08000  ? 349 GLU   C OE2 1 
ATOM   4631 N N   . TYR   C 1 136 ? 17.82025  -38.59792 -74.79189 1.000 64.68000  ? 350 TYR   C N   1 
ATOM   4632 C CA  . TYR   C 1 136 ? 17.04940  -38.35953 -76.00192 1.000 58.99000  ? 350 TYR   C CA  1 
ATOM   4633 C C   . TYR   C 1 136 ? 15.57137  -38.25056 -75.65706 1.000 58.83000  ? 350 TYR   C C   1 
ATOM   4634 O O   . TYR   C 1 136 ? 15.07523  -38.94480 -74.76633 1.000 55.75000  ? 350 TYR   C O   1 
ATOM   4635 C CB  . TYR   C 1 136 ? 17.28347  -39.48025 -77.01222 1.000 54.06000  ? 350 TYR   C CB  1 
ATOM   4636 C CG  . TYR   C 1 136 ? 18.71453  -39.50917 -77.48105 1.000 65.70000  ? 350 TYR   C CG  1 
ATOM   4637 C CD1 . TYR   C 1 136 ? 19.68741  -40.18243 -76.75213 1.000 67.68000  ? 350 TYR   C CD1 1 
ATOM   4638 C CD2 . TYR   C 1 136 ? 19.10970  -38.84385 -78.64281 1.000 62.76000  ? 350 TYR   C CD2 1 
ATOM   4639 C CE1 . TYR   C 1 136 ? 21.00546  -40.20437 -77.16398 1.000 70.88000  ? 350 TYR   C CE1 1 
ATOM   4640 C CE2 . TYR   C 1 136 ? 20.42575  -38.86879 -79.07066 1.000 62.56000  ? 350 TYR   C CE2 1 
ATOM   4641 C CZ  . TYR   C 1 136 ? 21.37363  -39.54905 -78.32275 1.000 73.09000  ? 350 TYR   C CZ  1 
ATOM   4642 O OH  . TYR   C 1 136 ? 22.70267  -39.57700 -78.71659 1.000 74.93000  ? 350 TYR   C OH  1 
ATOM   4643 N N   . ALA   C 1 137 ? 14.87449  -37.36832 -76.36589 1.000 64.35000  ? 351 ALA   C N   1 
ATOM   4644 C CA  . ALA   C 1 137 ? 13.46147  -37.15134 -76.08899 1.000 58.01000  ? 351 ALA   C CA  1 
ATOM   4645 C C   . ALA   C 1 137 ? 12.62447  -38.34417 -76.54244 1.000 53.07000  ? 351 ALA   C C   1 
ATOM   4646 O O   . ALA   C 1 137 ? 12.95055  -39.02590 -77.51460 1.000 55.65000  ? 351 ALA   C O   1 
ATOM   4647 C CB  . ALA   C 1 137 ? 12.97861  -35.86812 -76.76768 1.000 53.16000  ? 351 ALA   C CB  1 
ATOM   4648 N N   . ARG   C 1 138 ? 11.55537  -38.60734 -75.80465 1.000 49.63000  ? 352 ARG   C N   1 
ATOM   4649 C CA  . ARG   C 1 138 ? 10.58935  -39.64620 -76.10307 1.000 53.54000  ? 352 ARG   C CA  1 
ATOM   4650 C C   . ARG   C 1 138 ? 9.21136   -39.03420 -75.89006 1.000 62.31000  ? 352 ARG   C C   1 
ATOM   4651 O O   . ARG   C 1 138 ? 8.91625   -38.54251 -74.79495 1.000 60.66000  ? 352 ARG   C O   1 
ATOM   4652 C CB  . ARG   C 1 138 ? 10.80519  -40.87148 -75.20240 1.000 59.01000  ? 352 ARG   C CB  1 
ATOM   4653 C CG  . ARG   C 1 138 ? 10.50621  -42.21028 -75.84683 1.000 69.00000  ? 352 ARG   C CG  1 
ATOM   4654 C CD  . ARG   C 1 138 ? 11.74724  -42.92017 -76.39789 1.000 80.27000  ? 352 ARG   C CD  1 
ATOM   4655 N NE  . ARG   C 1 138 ? 11.39034  -43.77582 -77.52818 1.000 94.32000  ? 352 ARG   C NE  1 
ATOM   4656 C CZ  . ARG   C 1 138 ? 12.00333  -44.90475 -77.87144 1.000 96.07000  ? 352 ARG   C CZ  1 
ATOM   4657 N NH1 . ARG   C 1 138 ? 13.00822  -45.39301 -77.15446 1.000 86.88000  ? 352 ARG   C NH1 1 
ATOM   4658 N NH2 . ARG   C 1 138 ? 11.59243  -45.56141 -78.95868 1.000 96.44000  ? 352 ARG   C NH2 1 
ATOM   4659 N N   . LEU   C 1 139 ? 8.37548   -39.03686 -76.92616 1.000 58.02000  ? 353 LEU   C N   1 
ATOM   4660 C CA  . LEU   C 1 139 ? 7.12851   -38.29082 -76.86909 1.000 55.15000  ? 353 LEU   C CA  1 
ATOM   4661 C C   . LEU   C 1 139 ? 6.05339   -39.11498 -76.16346 1.000 56.14000  ? 353 LEU   C C   1 
ATOM   4662 O O   . LEU   C 1 139 ? 5.86937   -40.29988 -76.45683 1.000 56.52000  ? 353 LEU   C O   1 
ATOM   4663 C CB  . LEU   C 1 139 ? 6.68770   -37.89039 -78.27303 1.000 54.70000  ? 353 LEU   C CB  1 
ATOM   4664 C CG  . LEU   C 1 139 ? 5.31375   -37.23827 -78.45400 1.000 58.11000  ? 353 LEU   C CG  1 
ATOM   4665 C CD1 . LEU   C 1 139 ? 5.05867   -36.13257 -77.41171 1.000 59.76000  ? 353 LEU   C CD1 1 
ATOM   4666 C CD2 . LEU   C 1 139 ? 5.11494   -36.70785 -79.86587 1.000 48.24000  ? 353 LEU   C CD2 1 
ATOM   4667 N N   . GLU   C 1 140 ? 5.36430   -38.48923 -75.21236 1.000 55.01000  ? 354 GLU   C N   1 
ATOM   4668 C CA  . GLU   C 1 140 ? 4.45016   -39.18545 -74.31867 1.000 56.65000  ? 354 GLU   C CA  1 
ATOM   4669 C C   . GLU   C 1 140 ? 3.40515   -38.20854 -73.82151 1.000 55.80000  ? 354 GLU   C C   1 
ATOM   4670 O O   . GLU   C 1 140 ? 3.75113   -37.14171 -73.30716 1.000 50.03000  ? 354 GLU   C O   1 
ATOM   4671 C CB  . GLU   C 1 140 ? 5.15299   -39.79483 -73.10077 1.000 54.87000  ? 354 GLU   C CB  1 
ATOM   4672 C CG  . GLU   C 1 140 ? 6.44698   -40.54583 -73.31283 1.000 57.50000  ? 354 GLU   C CG  1 
ATOM   4673 C CD  . GLU   C 1 140 ? 7.04180   -40.99425 -71.98189 1.000 66.30000  ? 354 GLU   C CD  1 
ATOM   4674 O OE1 . GLU   C 1 140 ? 6.36868   -40.78252 -70.94191 1.000 69.20000  ? 354 GLU   C OE1 1 
ATOM   4675 O OE2 . GLU   C 1 140 ? 8.15477   -41.57131 -71.95993 1.000 62.62000  ? 354 GLU   C OE2 1 
ATOM   4676 N N   . ASN   C 1 141 ? 2.13814   -38.60345 -73.94578 1.000 57.33000  ? 355 ASN   C N   1 
ATOM   4677 C CA  . ASN   C 1 141 ? 1.00212   -37.82353 -73.47469 1.000 53.38000  ? 355 ASN   C CA  1 
ATOM   4678 C C   . ASN   C 1 141 ? 1.13124   -36.35443 -73.86624 1.000 55.47000  ? 355 ASN   C C   1 
ATOM   4679 O O   . ASN   C 1 141 ? 0.84318   -35.45364 -73.08001 1.000 54.96000  ? 355 ASN   C O   1 
ATOM   4680 C CB  . ASN   C 1 141 ? 0.83993   -37.97597 -71.97075 1.000 57.02000  ? 355 ASN   C CB  1 
ATOM   4681 C CG  . ASN   C 1 141 ? -0.61212  -38.08502 -71.55196 1.000 65.39000  ? 355 ASN   C CG  1 
ATOM   4682 O OD1 . ASN   C 1 141 ? -1.50602  -38.15773 -72.39509 1.000 69.71000  ? 355 ASN   C OD1 1 
ATOM   4683 N ND2 . ASN   C 1 141 ? -0.85328  -38.12840 -70.24100 1.000 67.57000  ? 355 ASN   C ND2 1 
ATOM   4684 N N   . GLY   C 1 142 ? 1.58440   -36.10809 -75.09512 1.000 55.94000  ? 356 GLY   C N   1 
ATOM   4685 C CA  . GLY   C 1 142 ? 1.68052   -34.75594 -75.60171 1.000 53.09000  ? 356 GLY   C CA  1 
ATOM   4686 C C   . GLY   C 1 142 ? 2.89350   -33.98013 -75.15234 1.000 56.90000  ? 356 GLY   C C   1 
ATOM   4687 O O   . GLY   C 1 142 ? 3.07061   -32.83701 -75.58298 1.000 55.84000  ? 356 GLY   C O   1 
ATOM   4688 N N   . ARG   C 1 143 ? 3.73337   -34.55842 -74.29840 1.000 56.82000  ? 357 ARG   C N   1 
ATOM   4689 C CA  . ARG   C 1 143 ? 4.96735   -33.93661 -73.84707 1.000 54.82000  ? 357 ARG   C CA  1 
ATOM   4690 C C   . ARG   C 1 143 ? 6.14737   -34.76652 -74.33217 1.000 53.24000  ? 357 ARG   C C   1 
ATOM   4691 O O   . ARG   C 1 143 ? 6.00635   -35.95343 -74.61754 1.000 55.24000  ? 357 ARG   C O   1 
ATOM   4692 C CB  . ARG   C 1 143 ? 5.00917   -33.81006 -72.30403 1.000 62.48000  ? 357 ARG   C CB  1 
ATOM   4693 C CG  . ARG   C 1 143 ? 4.30715   -32.58420 -71.72676 1.000 63.03000  ? 357 ARG   C CG  1 
ATOM   4694 C CD  . ARG   C 1 143 ? 5.24108   -31.78151 -70.80541 1.000 64.67000  ? 357 ARG   C CD  1 
ATOM   4695 N NE  . ARG   C 1 143 ? 5.04016   -30.33448 -70.88001 1.000 61.13000  ? 357 ARG   C NE  1 
ATOM   4696 C CZ  . ARG   C 1 143 ? 5.92815   -29.41663 -70.50263 1.000 68.48000  ? 357 ARG   C CZ  1 
ATOM   4697 N NH1 . ARG   C 1 143 ? 7.10207   -29.74884 -69.98359 1.000 61.57000  ? 357 ARG   C NH1 1 
ATOM   4698 N NH2 . ARG   C 1 143 ? 5.62323   -28.12458 -70.63429 1.000 73.36000  ? 357 ARG   C NH2 1 
ATOM   4699 N N   . PHE   C 1 144 ? 7.31841   -34.13355 -74.42385 1.000 57.45000  ? 358 PHE   C N   1 
ATOM   4700 C CA  . PHE   C 1 144 ? 8.58239   -34.85255 -74.59591 1.000 57.08000  ? 358 PHE   C CA  1 
ATOM   4701 C C   . PHE   C 1 144 ? 9.19922   -35.13898 -73.23192 1.000 57.05000  ? 358 PHE   C C   1 
ATOM   4702 O O   . PHE   C 1 144 ? 9.35616   -34.23023 -72.40863 1.000 55.65000  ? 358 PHE   C O   1 
ATOM   4703 C CB  . PHE   C 1 144 ? 9.55554   -34.05934 -75.46356 1.000 55.11000  ? 358 PHE   C CB  1 
ATOM   4704 C CG  . PHE   C 1 144 ? 9.18171   -34.06290 -76.90960 1.000 62.38000  ? 358 PHE   C CG  1 
ATOM   4705 C CD1 . PHE   C 1 144 ? 9.49676   -35.14768 -77.71388 1.000 55.68000  ? 358 PHE   C CD1 1 
ATOM   4706 C CD2 . PHE   C 1 144 ? 8.47082   -33.00371 -77.45138 1.000 61.42000  ? 358 PHE   C CD2 1 
ATOM   4707 C CE1 . PHE   C 1 144 ? 9.13091   -35.16028 -79.01693 1.000 62.02000  ? 358 PHE   C CE1 1 
ATOM   4708 C CE2 . PHE   C 1 144 ? 8.09998   -33.01031 -78.75743 1.000 61.03000  ? 358 PHE   C CE2 1 
ATOM   4709 C CZ  . PHE   C 1 144 ? 8.42502   -34.08510 -79.54670 1.000 65.48000  ? 358 PHE   C CZ  1 
ATOM   4710 N N   . VAL   C 1 145 ? 9.54213   -36.40707 -72.99525 1.000 56.33000  ? 359 VAL   C N   1 
ATOM   4711 C CA  . VAL   C 1 145 ? 9.92995   -36.89647 -71.67734 1.000 58.19000  ? 359 VAL   C CA  1 
ATOM   4712 C C   . VAL   C 1 145 ? 11.33293  -37.48251 -71.75235 1.000 61.30000  ? 359 VAL   C C   1 
ATOM   4713 O O   . VAL   C 1 145 ? 11.61399  -38.33828 -72.60556 1.000 59.68000  ? 359 VAL   C O   1 
ATOM   4714 C CB  . VAL   C 1 145 ? 8.92584   -37.92758 -71.13977 1.000 61.92000  ? 359 VAL   C CB  1 
ATOM   4715 C CG1 . VAL   C 1 145 ? 9.47566   -38.60197 -69.90490 1.000 61.43000  ? 359 VAL   C CG1 1 
ATOM   4716 C CG2 . VAL   C 1 145 ? 7.63283   -37.22962 -70.79272 1.000 61.49000  ? 359 VAL   C CG2 1 
ATOM   4717 N N   . TYR   C 1 146 ? 12.20785  -37.00682 -70.85910 1.000 56.44000  ? 360 TYR   C N   1 
ATOM   4718 C CA  . TYR   C 1 146 ? 13.59481  -37.44391 -70.75006 1.000 55.08000  ? 360 TYR   C CA  1 
ATOM   4719 C C   . TYR   C 1 146 ? 13.73062  -38.24330 -69.46028 1.000 52.99000  ? 360 TYR   C C   1 
ATOM   4720 O O   . TYR   C 1 146 ? 13.37351  -37.75759 -68.38518 1.000 55.72000  ? 360 TYR   C O   1 
ATOM   4721 C CB  . TYR   C 1 146 ? 14.54887  -36.24895 -70.76460 1.000 48.66000  ? 360 TYR   C CB  1 
ATOM   4722 C CG  . TYR   C 1 146 ? 14.31605  -35.28860 -71.91535 1.000 52.72000  ? 360 TYR   C CG  1 
ATOM   4723 C CD1 . TYR   C 1 146 ? 13.32609  -34.32458 -71.84618 1.000 47.80000  ? 360 TYR   C CD1 1 
ATOM   4724 C CD2 . TYR   C 1 146 ? 15.10019  -35.34430 -73.07227 1.000 58.75000  ? 360 TYR   C CD2 1 
ATOM   4725 C CE1 . TYR   C 1 146 ? 13.10425  -33.45527 -72.87295 1.000 50.83000  ? 360 TYR   C CE1 1 
ATOM   4726 C CE2 . TYR   C 1 146 ? 14.89835  -34.46898 -74.11804 1.000 56.98000  ? 360 TYR   C CE2 1 
ATOM   4727 C CZ  . TYR   C 1 146 ? 13.88539  -33.52297 -74.01588 1.000 61.78000  ? 360 TYR   C CZ  1 
ATOM   4728 O OH  . TYR   C 1 146 ? 13.64555  -32.63265 -75.04765 1.000 61.09000  ? 360 TYR   C OH  1 
ATOM   4729 N N   . ARG   C 1 147 ? 14.23058  -39.46829 -69.56658 1.000 55.74000  ? 361 ARG   C N   1 
ATOM   4730 C CA  . ARG   C 1 147 ? 14.28440  -40.38462 -68.43584 1.000 57.80000  ? 361 ARG   C CA  1 
ATOM   4731 C C   . ARG   C 1 147 ? 15.69135  -40.92973 -68.27083 1.000 60.23000  ? 361 ARG   C C   1 
ATOM   4732 O O   . ARG   C 1 147 ? 16.32045  -41.34748 -69.24988 1.000 54.51000  ? 361 ARG   C O   1 
ATOM   4733 C CB  . ARG   C 1 147 ? 13.30537  -41.54053 -68.61030 1.000 49.83000  ? 361 ARG   C CB  1 
ATOM   4734 C CG  . ARG   C 1 147 ? 11.86139  -41.11546 -68.61835 1.000 54.17000  ? 361 ARG   C CG  1 
ATOM   4735 C CD  . ARG   C 1 147 ? 10.96431  -42.32847 -68.43881 1.000 61.37000  ? 361 ARG   C CD  1 
ATOM   4736 N NE  . ARG   C 1 147 ? 9.78523   -42.03565 -67.63387 1.000 72.74000  ? 361 ARG   C NE  1 
ATOM   4737 C CZ  . ARG   C 1 147 ? 8.57430   -41.83045 -68.12995 1.000 66.00000  ? 361 ARG   C CZ  1 
ATOM   4738 N NH1 . ARG   C 1 147 ? 8.34745   -41.90706 -69.42900 1.000 66.40000  ? 361 ARG   C NH1 1 
ATOM   4739 N NH2 . ARG   C 1 147 ? 7.56821   -41.55864 -67.30199 1.000 61.32000  ? 361 ARG   C NH2 1 
ATOM   4740 N N   . ILE   C 1 148 ? 16.18021  -40.89812 -67.03176 1.000 62.32000  ? 362 ILE   C N   1 
ATOM   4741 C CA  . ILE   C 1 148 ? 17.37812  -41.61830 -66.61683 1.000 58.24000  ? 362 ILE   C CA  1 
ATOM   4742 C C   . ILE   C 1 148 ? 16.93795  -42.54960 -65.50716 1.000 58.12000  ? 362 ILE   C C   1 
ATOM   4743 O O   . ILE   C 1 148 ? 16.52084  -42.09290 -64.43407 1.000 59.20000  ? 362 ILE   C O   1 
ATOM   4744 C CB  . ILE   C 1 148 ? 18.49311  -40.68649 -66.13342 1.000 58.03000  ? 362 ILE   C CB  1 
ATOM   4745 C CG1 . ILE   C 1 148 ? 19.16728  -40.00318 -67.30914 1.000 62.20000  ? 362 ILE   C CG1 1 
ATOM   4746 C CG2 . ILE   C 1 148 ? 19.56199  -41.49075 -65.42053 1.000 64.60000  ? 362 ILE   C CG2 1 
ATOM   4747 C CD1 . ILE   C 1 148 ? 19.73530  -38.62830 -66.96167 1.000 62.77000  ? 362 ILE   C CD1 1 
ATOM   4748 N N   . HIS   C 1 149 ? 16.98592  -43.84253 -65.77253 1.000 58.92000  ? 363 HIS   C N   1 
ATOM   4749 C CA  . HIS   C 1 149 ? 16.41877  -44.82676 -64.87289 1.000 64.21000  ? 363 HIS   C CA  1 
ATOM   4750 C C   . HIS   C 1 149 ? 17.54366  -45.68598 -64.31400 1.000 64.37000  ? 363 HIS   C C   1 
ATOM   4751 O O   . HIS   C 1 149 ? 18.35973  -46.21079 -65.07806 1.000 58.48000  ? 363 HIS   C O   1 
ATOM   4752 C CB  . HIS   C 1 149 ? 15.36482  -45.65650 -65.61726 1.000 67.90000  ? 363 HIS   C CB  1 
ATOM   4753 C CG  . HIS   C 1 149 ? 14.90667  -46.87569 -64.88167 1.000 71.58000  ? 363 HIS   C CG  1 
ATOM   4754 N ND1 . HIS   C 1 149 ? 15.26866  -48.15560 -65.25700 1.000 69.90000  ? 363 HIS   C ND1 1 
ATOM   4755 C CD2 . HIS   C 1 149 ? 14.12953  -47.00798 -63.77880 1.000 73.48000  ? 363 HIS   C CD2 1 
ATOM   4756 C CE1 . HIS   C 1 149 ? 14.70652  -49.02482 -64.42832 1.000 77.10000  ? 363 HIS   C CE1 1 
ATOM   4757 N NE2 . HIS   C 1 149 ? 14.01944  -48.35305 -63.51721 1.000 76.87000  ? 363 HIS   C NE2 1 
ATOM   4758 N N   . ARG   C 1 150 ? 17.60450  -45.78237 -62.98402 1.000 57.92000  ? 364 ARG   C N   1 
ATOM   4759 C CA  . ARG   C 1 150 ? 18.52337  -46.68462 -62.29118 1.000 53.79000  ? 364 ARG   C CA  1 
ATOM   4760 C C   . ARG   C 1 150 ? 19.96344  -46.49255 -62.75795 1.000 54.91000  ? 364 ARG   C C   1 
ATOM   4761 O O   . ARG   C 1 150 ? 20.65944  -47.44047 -63.14114 1.000 53.67000  ? 364 ARG   C O   1 
ATOM   4762 C CB  . ARG   C 1 150 ? 18.08632  -48.14155 -62.45766 1.000 56.45000  ? 364 ARG   C CB  1 
ATOM   4763 C CG  . ARG   C 1 150 ? 16.92520  -48.50676 -61.55090 1.000 60.12000  ? 364 ARG   C CG  1 
ATOM   4764 C CD  . ARG   C 1 150 ? 16.52614  -49.97873 -61.59838 1.000 63.40000  ? 364 ARG   C CD  1 
ATOM   4765 N NE  . ARG   C 1 150 ? 17.11197  -50.78207 -60.53055 1.000 53.72000  ? 364 ARG   C NE  1 
ATOM   4766 C CZ  . ARG   C 1 150 ? 18.18895  -51.53807 -60.68964 1.000 58.72000  ? 364 ARG   C CZ  1 
ATOM   4767 N NH1 . ARG   C 1 150 ? 18.81809  -51.60076 -61.84758 1.000 53.88000  ? 364 ARG   C NH1 1 
ATOM   4768 N NH2 . ARG   C 1 150 ? 18.63280  -52.26639 -59.66780 1.000 60.14000  ? 364 ARG   C NH2 1 
ATOM   4769 N N   . SER   C 1 151 ? 20.41649  -45.24958 -62.72453 1.000 51.98000  ? 365 SER   C N   1 
ATOM   4770 C CA  . SER   C 1 151 ? 21.80854  -45.00153 -63.08629 1.000 49.71000  ? 365 SER   C CA  1 
ATOM   4771 C C   . SER   C 1 151 ? 22.70939  -45.27493 -61.88426 1.000 49.73000  ? 365 SER   C C   1 
ATOM   4772 O O   . SER   C 1 151 ? 22.54629  -44.64423 -60.83510 1.000 44.83000  ? 365 SER   C O   1 
ATOM   4773 C CB  . SER   C 1 151 ? 21.98867  -43.56940 -63.56785 1.000 54.59000  ? 365 SER   C CB  1 
ATOM   4774 O OG  . SER   C 1 151 ? 23.36369  -43.22645 -63.61658 1.000 63.36000  ? 365 SER   C OG  1 
ATOM   4775 N N   . PRO   C 1 152 ? 23.66936  -46.19194 -62.00041 1.000 55.06000  ? 366 PRO   C N   1 
ATOM   4776 C CA  . PRO   C 1 152 ? 24.40819  -46.64832 -60.81046 1.000 52.15000  ? 366 PRO   C CA  1 
ATOM   4777 C C   . PRO   C 1 152 ? 25.21717  -45.53454 -60.17804 1.000 46.80000  ? 366 PRO   C C   1 
ATOM   4778 O O   . PRO   C 1 152 ? 25.71229  -44.63337 -60.85971 1.000 51.22000  ? 366 PRO   C O   1 
ATOM   4779 C CB  . PRO   C 1 152 ? 25.31621  -47.75720 -61.35468 1.000 42.20000  ? 366 PRO   C CB  1 
ATOM   4780 C CG  . PRO   C 1 152 ? 24.59734  -48.21780 -62.60790 1.000 46.18000  ? 366 PRO   C CG  1 
ATOM   4781 C CD  . PRO   C 1 152 ? 24.03847  -46.95860 -63.19859 1.000 47.79000  ? 366 PRO   C CD  1 
ATOM   4782 N N   . MET   C 1 153 ? 25.30701  -45.58994 -58.85504 1.000 46.87000  ? 367 MET   C N   1 
ATOM   4783 C CA  . MET   C 1 153 ? 26.02597  -44.56919 -58.11366 1.000 48.50000  ? 367 MET   C CA  1 
ATOM   4784 C C   . MET   C 1 153 ? 27.51197  -44.80621 -58.25655 1.000 49.10000  ? 367 MET   C C   1 
ATOM   4785 O O   . MET   C 1 153 ? 27.96193  -45.95221 -58.33083 1.000 51.20000  ? 367 MET   C O   1 
ATOM   4786 C CB  . MET   C 1 153 ? 25.64479  -44.61160 -56.64271 1.000 50.85000  ? 367 MET   C CB  1 
ATOM   4787 C CG  . MET   C 1 153 ? 24.61179  -43.56466 -56.27753 1.000 59.13000  ? 367 MET   C CG  1 
ATOM   4788 S SD  . MET   C 1 153 ? 24.37658  -43.54116 -54.51255 1.000 51.38000  ? 367 MET   C SD  1 
ATOM   4789 C CE  . MET   C 1 153 ? 22.65959  -43.03813 -54.37361 1.000 47.60000  ? 367 MET   C CE  1 
ATOM   4790 N N   . CYS   C 1 154 ? 28.27903  -43.72823 -58.31114 1.000 50.28000  ? 368 CYS   C N   1 
ATOM   4791 C CA  . CYS   C 1 154 ? 29.72202  -43.90530 -58.28902 1.000 53.18000  ? 368 CYS   C CA  1 
ATOM   4792 C C   . CYS   C 1 154 ? 30.17183  -44.38173 -56.91010 1.000 51.64000  ? 368 CYS   C C   1 
ATOM   4793 O O   . CYS   C 1 154 ? 29.51972  -44.12400 -55.89111 1.000 53.77000  ? 368 CYS   C O   1 
ATOM   4794 C CB  . CYS   C 1 154 ? 30.43512  -42.61522 -58.68355 1.000 53.97000  ? 368 CYS   C CB  1 
ATOM   4795 S SG  . CYS   C 1 154 ? 29.66212  -41.12635 -58.10821 1.000 65.88000  ? 368 CYS   C SG  1 
ATOM   4796 N N   . GLU   C 1 155 ? 31.28079  -45.11979 -56.89119 1.000 52.87000  ? 369 GLU   C N   1 
ATOM   4797 C CA  . GLU   C 1 155 ? 31.76462  -45.67518 -55.63129 1.000 52.65000  ? 369 GLU   C CA  1 
ATOM   4798 C C   . GLU   C 1 155 ? 32.00954  -44.57949 -54.60894 1.000 50.48000  ? 369 GLU   C C   1 
ATOM   4799 O O   . GLU   C 1 155 ? 31.93639  -44.83184 -53.39902 1.000 48.47000  ? 369 GLU   C O   1 
ATOM   4800 C CB  . GLU   C 1 155 ? 33.04361  -46.47617 -55.86837 1.000 55.95000  ? 369 GLU   C CB  1 
ATOM   4801 C CG  . GLU   C 1 155 ? 32.87769  -47.53985 -56.93070 1.000 57.78000  ? 369 GLU   C CG  1 
ATOM   4802 C CD  . GLU   C 1 155 ? 34.15568  -48.30983 -57.20377 1.000 66.19000  ? 369 GLU   C CD  1 
ATOM   4803 O OE1 . GLU   C 1 155 ? 35.17861  -48.05607 -56.51558 1.000 63.07000  ? 369 GLU   C OE1 1 
ATOM   4804 O OE2 . GLU   C 1 155 ? 34.13576  -49.15655 -58.13102 1.000 65.69000  ? 369 GLU   C OE2 1 
ATOM   4805 N N   . TYR   C 1 156 ? 32.28366  -43.35636 -55.07355 1.000 50.05000  ? 370 TYR   C N   1 
ATOM   4806 C CA  . TYR   C 1 156 ? 32.49160  -42.25565 -54.14620 1.000 45.45000  ? 370 TYR   C CA  1 
ATOM   4807 C C   . TYR   C 1 156 ? 31.26550  -42.06685 -53.27129 1.000 51.25000  ? 370 TYR   C C   1 
ATOM   4808 O O   . TYR   C 1 156 ? 31.36335  -42.05521 -52.03428 1.000 52.14000  ? 370 TYR   C O   1 
ATOM   4809 C CB  . TYR   C 1 156 ? 32.81874  -40.95544 -54.88378 1.000 48.69000  ? 370 TYR   C CB  1 
ATOM   4810 C CG  . TYR   C 1 156 ? 33.06368  -39.84475 -53.88943 1.000 50.06000  ? 370 TYR   C CG  1 
ATOM   4811 C CD1 . TYR   C 1 156 ? 32.00764  -39.15186 -53.32435 1.000 51.88000  ? 370 TYR   C CD1 1 
ATOM   4812 C CD2 . TYR   C 1 156 ? 34.34464  -39.51892 -53.48518 1.000 49.47000  ? 370 TYR   C CD2 1 
ATOM   4813 C CE1 . TYR   C 1 156 ? 32.21457  -38.18615 -52.38804 1.000 55.25000  ? 370 TYR   C CE1 1 
ATOM   4814 C CE2 . TYR   C 1 156 ? 34.55858  -38.53220 -52.56286 1.000 53.01000  ? 370 TYR   C CE2 1 
ATOM   4815 C CZ  . TYR   C 1 156 ? 33.48254  -37.87231 -52.01880 1.000 51.89000  ? 370 TYR   C CZ  1 
ATOM   4816 O OH  . TYR   C 1 156 ? 33.65947  -36.89560 -51.08649 1.000 59.91000  ? 370 TYR   C OH  1 
ATOM   4817 N N   . MET   C 1 157 ? 30.10058  -41.90761 -53.89939 1.000 48.33000  ? 371 MET   C N   1 
ATOM   4818 C CA  . MET   C 1 157 ? 28.90250  -41.62678 -53.12645 1.000 45.76000  ? 371 MET   C CA  1 
ATOM   4819 C C   . MET   C 1 157 ? 28.45835  -42.82100 -52.29685 1.000 46.89000  ? 371 MET   C C   1 
ATOM   4820 O O   . MET   C 1 157 ? 27.94322  -42.63730 -51.18586 1.000 49.75000  ? 371 MET   C O   1 
ATOM   4821 C CB  . MET   C 1 157 ? 27.80064  -41.14746 -54.05344 1.000 50.70000  ? 371 MET   C CB  1 
ATOM   4822 C CG  . MET   C 1 157 ? 28.08076  -39.76832 -54.58000 1.000 44.49000  ? 371 MET   C CG  1 
ATOM   4823 S SD  . MET   C 1 157 ? 28.11565  -38.57271 -53.23065 1.000 51.68000  ? 371 MET   C SD  1 
ATOM   4824 C CE  . MET   C 1 157 ? 26.77650  -39.12197 -52.15197 1.000 51.70000  ? 371 MET   C CE  1 
ATOM   4825 N N   . ILE   C 1 158 ? 28.63835  -44.04587 -52.78719 1.000 44.83000  ? 372 ILE   C N   1 
ATOM   4826 C CA  . ILE   C 1 158 ? 28.35019  -45.17911 -51.91355 1.000 51.77000  ? 372 ILE   C CA  1 
ATOM   4827 C C   . ILE   C 1 158 ? 29.20505  -45.09152 -50.65843 1.000 47.61000  ? 372 ILE   C C   1 
ATOM   4828 O O   . ILE   C 1 158 ? 28.72290  -45.28782 -49.53354 1.000 46.41000  ? 372 ILE   C O   1 
ATOM   4829 C CB  . ILE   C 1 158 ? 28.56422  -46.51190 -52.64892 1.000 52.72000  ? 372 ILE   C CB  1 
ATOM   4830 C CG1 . ILE   C 1 158 ? 27.82738  -46.49047 -53.99800 1.000 47.22000  ? 372 ILE   C CG1 1 
ATOM   4831 C CG2 . ILE   C 1 158 ? 28.18805  -47.69316 -51.71031 1.000 45.50000  ? 372 ILE   C CG2 1 
ATOM   4832 C CD1 . ILE   C 1 158 ? 27.95942  -47.76125 -54.79136 1.000 45.67000  ? 372 ILE   C CD1 1 
ATOM   4833 N N   . ASN   C 1 159 ? 30.48008  -44.74452 -50.84317 1.000 50.98000  ? 373 ASN   C N   1 
ATOM   4834 C CA  . ASN   C 1 159 ? 31.42196  -44.57889 -49.74301 1.000 50.91000  ? 373 ASN   C CA  1 
ATOM   4835 C C   . ASN   C 1 159 ? 31.04291  -43.39513 -48.85771 1.000 44.81000  ? 373 ASN   C C   1 
ATOM   4836 O O   . ASN   C 1 159 ? 31.10376  -43.47149 -47.62572 1.000 46.58000  ? 373 ASN   C O   1 
ATOM   4837 C CB  . ASN   C 1 159 ? 32.82304  -44.38178 -50.31978 1.000 47.95000  ? 373 ASN   C CB  1 
ATOM   4838 C CG  . ASN   C 1 159 ? 33.81493  -43.90213 -49.28252 1.000 49.87000  ? 373 ASN   C CG  1 
ATOM   4839 O OD1 . ASN   C 1 159 ? 33.89878  -44.45546 -48.18268 1.000 52.94000  ? 373 ASN   C OD1 1 
ATOM   4840 N ND2 . ASN   C 1 159 ? 34.51802  -42.82107 -49.59612 1.000 46.16000  ? 373 ASN   C ND2 1 
ATOM   4841 N N   . PHE   C 1 160 ? 30.72303  -42.26693 -49.48242 1.000 42.62000  ? 374 PHE   C N   1 
ATOM   4842 C CA  . PHE   C 1 160 ? 30.31100  -41.08813 -48.73912 1.000 44.42000  ? 374 PHE   C CA  1 
ATOM   4843 C C   . PHE   C 1 160 ? 29.13088  -41.40534 -47.83135 1.000 50.22000  ? 374 PHE   C C   1 
ATOM   4844 O O   . PHE   C 1 160 ? 29.10775  -40.98968 -46.66624 1.000 52.08000  ? 374 PHE   C O   1 
ATOM   4845 C CB  . PHE   C 1 160 ? 29.96117  -39.97082 -49.72283 1.000 43.92000  ? 374 PHE   C CB  1 
ATOM   4846 C CG  . PHE   C 1 160 ? 29.78115  -38.63900 -49.08047 1.000 44.63000  ? 374 PHE   C CG  1 
ATOM   4847 C CD1 . PHE   C 1 160 ? 30.87313  -37.91719 -48.63512 1.000 55.14000  ? 374 PHE   C CD1 1 
ATOM   4848 C CD2 . PHE   C 1 160 ? 28.52816  -38.11400 -48.89846 1.000 48.03000  ? 374 PHE   C CD2 1 
ATOM   4849 C CE1 . PHE   C 1 160 ? 30.70412  -36.69136 -48.02678 1.000 53.84000  ? 374 PHE   C CE1 1 
ATOM   4850 C CE2 . PHE   C 1 160 ? 28.35614  -36.88217 -48.30312 1.000 49.75000  ? 374 PHE   C CE2 1 
ATOM   4851 C CZ  . PHE   C 1 160 ? 29.43912  -36.17835 -47.85779 1.000 48.94000  ? 374 PHE   C CZ  1 
ATOM   4852 N N   . ILE   C 1 161 ? 28.15890  -42.17915 -48.33070 1.000 46.40000  ? 375 ILE   C N   1 
ATOM   4853 C CA  . ILE   C 1 161 ? 26.96179  -42.47232 -47.54793 1.000 49.78000  ? 375 ILE   C CA  1 
ATOM   4854 C C   . ILE   C 1 161 ? 27.29760  -43.30070 -46.30613 1.000 48.51000  ? 375 ILE   C C   1 
ATOM   4855 O O   . ILE   C 1 161 ? 26.82349  -43.00100 -45.20410 1.000 51.20000  ? 375 ILE   C O   1 
ATOM   4856 C CB  . ILE   C 1 161 ? 25.90687  -43.15101 -48.44125 1.000 48.87000  ? 375 ILE   C CB  1 
ATOM   4857 C CG1 . ILE   C 1 161 ? 25.30503  -42.10671 -49.38902 1.000 48.96000  ? 375 ILE   C CG1 1 
ATOM   4858 C CG2 . ILE   C 1 161 ? 24.84073  -43.86421 -47.59959 1.000 41.55000  ? 375 ILE   C CG2 1 
ATOM   4859 C CD1 . ILE   C 1 161 ? 24.49615  -42.69532 -50.57829 1.000 46.19000  ? 375 ILE   C CD1 1 
ATOM   4860 N N   . HIS   C 1 162 ? 28.14657  -44.32570 -46.44133 1.000 47.76000  ? 376 HIS   C N   1 
ATOM   4861 C CA  . HIS   C 1 162 ? 28.41440  -45.19205 -45.29255 1.000 49.76000  ? 376 HIS   C CA  1 
ATOM   4862 C C   . HIS   C 1 162 ? 29.33730  -44.54039 -44.26925 1.000 52.36000  ? 376 HIS   C C   1 
ATOM   4863 O O   . HIS   C 1 162 ? 29.25414  -44.85974 -43.07635 1.000 51.35000  ? 376 HIS   C O   1 
ATOM   4864 C CB  . HIS   C 1 162 ? 28.99439  -46.51994 -45.75287 1.000 49.73000  ? 376 HIS   C CB  1 
ATOM   4865 C CG  . HIS   C 1 162 ? 28.08146  -47.28264 -46.65520 1.000 52.95000  ? 376 HIS   C CG  1 
ATOM   4866 N ND1 . HIS   C 1 162 ? 26.77141  -47.55167 -46.32744 1.000 55.52000  ? 376 HIS   C ND1 1 
ATOM   4867 C CD2 . HIS   C 1 162 ? 28.27659  -47.80128 -47.89033 1.000 51.31000  ? 376 HIS   C CD2 1 
ATOM   4868 C CE1 . HIS   C 1 162 ? 26.20850  -48.22436 -47.31370 1.000 57.21000  ? 376 HIS   C CE1 1 
ATOM   4869 N NE2 . HIS   C 1 162 ? 27.10561  -48.40212 -48.26465 1.000 54.60000  ? 376 HIS   C NE2 1 
ATOM   4870 N N   . LYS   C 1 163 ? 30.23040  -43.64631 -44.69988 1.000 51.68000  ? 377 LYS   C N   1 
ATOM   4871 C CA  . LYS   C 1 163 ? 31.02131  -42.92263 -43.71157 1.000 52.35000  ? 377 LYS   C CA  1 
ATOM   4872 C C   . LYS   C 1 163 ? 30.15326  -41.96082 -42.92739 1.000 50.92000  ? 377 LYS   C C   1 
ATOM   4873 O O   . LYS   C 1 163 ? 30.41913  -41.72618 -41.74329 1.000 57.02000  ? 377 LYS   C O   1 
ATOM   4874 C CB  . LYS   C 1 163 ? 32.17642  -42.16550 -44.36921 1.000 50.70000  ? 377 LYS   C CB  1 
ATOM   4875 C CG  . LYS   C 1 163 ? 33.33243  -43.04444 -44.75133 1.000 56.24000  ? 377 LYS   C CG  1 
ATOM   4876 C CD  . LYS   C 1 163 ? 34.30357  -42.28322 -45.64599 1.000 64.04000  ? 377 LYS   C CD  1 
ATOM   4877 C CE  . LYS   C 1 163 ? 35.61657  -43.00820 -45.91004 1.000 54.86000  ? 377 LYS   C CE  1 
ATOM   4878 N NZ  . LYS   C 1 163 ? 36.23175  -42.31388 -47.09577 1.000 66.47000  ? 377 LYS   C NZ  1 
ATOM   4879 N N   . LEU   C 1 164 ? 29.12036  -41.39559 -43.55735 1.000 45.29000  ? 378 LEU   C N   1 
ATOM   4880 C CA  . LEU   C 1 164 ? 28.17430  -40.62078 -42.77924 1.000 47.27000  ? 378 LEU   C CA  1 
ATOM   4881 C C   . LEU   C 1 164 ? 27.46714  -41.49504 -41.75458 1.000 53.82000  ? 378 LEU   C C   1 
ATOM   4882 O O   . LEU   C 1 164 ? 27.19603  -41.05436 -40.63148 1.000 50.44000  ? 378 LEU   C O   1 
ATOM   4883 C CB  . LEU   C 1 164 ? 27.15744  -39.95047 -43.68217 1.000 48.57000  ? 378 LEU   C CB  1 
ATOM   4884 C CG  . LEU   C 1 164 ? 27.58259  -38.72926 -44.44876 1.000 48.51000  ? 378 LEU   C CG  1 
ATOM   4885 C CD1 . LEU   C 1 164 ? 26.47473  -38.38291 -45.48079 1.000 50.31000  ? 378 LEU   C CD1 1 
ATOM   4886 C CD2 . LEU   C 1 164 ? 27.82052  -37.62356 -43.45440 1.000 45.29000  ? 378 LEU   C CD2 1 
ATOM   4887 N N   . LYS   C 1 165 ? 27.16413  -42.72193 -42.09998 1.000 53.88000  ? 379 LYS   C N   1 
ATOM   4888 C CA  . LYS   C 1 165 ? 26.40698  -43.55116 -41.18931 1.000 56.50000  ? 379 LYS   C CA  1 
ATOM   4889 C C   . LYS   C 1 165 ? 27.23081  -44.02255 -40.00735 1.000 59.93000  ? 379 LYS   C C   1 
ATOM   4890 O O   . LYS   C 1 165 ? 26.68867  -44.32883 -38.95750 1.000 54.07000  ? 379 LYS   C O   1 
ATOM   4891 C CB  . LYS   C 1 165 ? 25.82501  -44.74392 -41.93873 1.000 53.85000  ? 379 LYS   C CB  1 
ATOM   4892 C CG  . LYS   C 1 165 ? 24.79116  -44.40356 -42.98775 1.000 56.11000  ? 379 LYS   C CG  1 
ATOM   4893 C CD  . LYS   C 1 165 ? 24.27918  -45.67335 -43.64119 1.000 65.00000  ? 379 LYS   C CD  1 
ATOM   4894 C CE  . LYS   C 1 165 ? 23.10630  -45.39102 -44.56325 1.000 79.83000  ? 379 LYS   C CE  1 
ATOM   4895 N NZ  . LYS   C 1 165 ? 22.59132  -46.62380 -45.22067 1.000 77.59000  ? 379 LYS   C NZ  1 
ATOM   4896 N N   . HIS   C 1 166 ? 28.53783  -44.09656 -40.17521 1.000 53.29000  ? 380 HIS   C N   1 
ATOM   4897 C CA  . HIS   C 1 166 ? 29.39868  -44.48292 -39.06222 1.000 53.16000  ? 380 HIS   C CA  1 
ATOM   4898 C C   . HIS   C 1 166 ? 29.46460  -43.39324 -37.99790 1.000 54.79000  ? 380 HIS   C C   1 
ATOM   4899 O O   . HIS   C 1 166 ? 29.74345  -43.68259 -36.83295 1.000 64.53000  ? 380 HIS   C O   1 
ATOM   4900 C CB  . HIS   C 1 166 ? 30.81772  -44.79684 -39.55015 1.000 57.60000  ? 380 HIS   C CB  1 
ATOM   4901 C CG  . HIS   C 1 166 ? 30.90978  -45.98458 -40.46048 1.000 63.43000  ? 380 HIS   C CG  1 
ATOM   4902 N ND1 . HIS   C 1 166 ? 31.83890  -46.06633 -41.47639 1.000 65.77000  ? 380 HIS   C ND1 1 
ATOM   4903 C CD2 . HIS   C 1 166 ? 30.20173  -47.14054 -40.50491 1.000 63.07000  ? 380 HIS   C CD2 1 
ATOM   4904 C CE1 . HIS   C 1 166 ? 31.69492  -47.21613 -42.11275 1.000 62.86000  ? 380 HIS   C CE1 1 
ATOM   4905 N NE2 . HIS   C 1 166 ? 30.70982  -47.88826 -41.54306 1.000 66.84000  ? 380 HIS   C NE2 1 
ATOM   4906 N N   . LEU   C 1 167 ? 29.22370  -42.14212 -38.36556 1.000 52.66000  ? 381 LEU   C N   1 
ATOM   4907 C CA  . LEU   C 1 167 ? 29.29464  -41.06241 -37.38723 1.000 55.91000  ? 381 LEU   C CA  1 
ATOM   4908 C C   . LEU   C 1 167 ? 28.30249  -41.31269 -36.25443 1.000 57.03000  ? 381 LEU   C C   1 
ATOM   4909 O O   . LEU   C 1 167 ? 27.18950  -41.78157 -36.50370 1.000 61.88000  ? 381 LEU   C O   1 
ATOM   4910 C CB  . LEU   C 1 167 ? 29.00378  -39.71820 -38.05188 1.000 58.53000  ? 381 LEU   C CB  1 
ATOM   4911 C CG  . LEU   C 1 167 ? 30.19190  -39.10003 -38.80855 1.000 62.23000  ? 381 LEU   C CG  1 
ATOM   4912 C CD1 . LEU   C 1 167 ? 29.70906  -38.02673 -39.77930 1.000 56.38000  ? 381 LEU   C CD1 1 
ATOM   4913 C CD2 . LEU   C 1 167 ? 31.25281  -38.54536 -37.85626 1.000 62.25000  ? 381 LEU   C CD2 1 
ATOM   4914 N N   . PRO   C 1 168 ? 28.68835  -41.06208 -35.00031 1.000 64.17000  ? 382 PRO   C N   1 
ATOM   4915 C CA  . PRO   C 1 168 ? 27.80520  -41.42137 -33.87352 1.000 57.73000  ? 382 PRO   C CA  1 
ATOM   4916 C C   . PRO   C 1 168 ? 26.65521  -40.46538 -33.65638 1.000 60.01000  ? 382 PRO   C C   1 
ATOM   4917 O O   . PRO   C 1 168 ? 25.70411  -40.83854 -32.96360 1.000 66.15000  ? 382 PRO   C O   1 
ATOM   4918 C CB  . PRO   C 1 168 ? 28.73705  -41.41577 -32.65540 1.000 56.16000  ? 382 PRO   C CB  1 
ATOM   4919 C CG  . PRO   C 1 168 ? 30.07412  -41.04369 -33.11913 1.000 61.80000  ? 382 PRO   C CG  1 
ATOM   4920 C CD  . PRO   C 1 168 ? 30.11331  -40.96126 -34.61511 1.000 64.44000  ? 382 PRO   C CD  1 
ATOM   4921 N N   . GLU   C 1 169 ? 26.71633  -39.23723 -34.16501 1.000 60.08000  ? 383 GLU   C N   1 
ATOM   4922 C CA  . GLU   C 1 169 ? 25.68234  -38.24927 -33.88384 1.000 61.96000  ? 383 GLU   C CA  1 
ATOM   4923 C C   . GLU   C 1 169 ? 25.26653  -37.56087 -35.16969 1.000 61.28000  ? 383 GLU   C C   1 
ATOM   4924 O O   . GLU   C 1 169 ? 26.09665  -37.34465 -36.06053 1.000 61.51000  ? 383 GLU   C O   1 
ATOM   4925 C CB  . GLU   C 1 169 ? 26.14327  -37.18859 -32.86948 1.000 63.33000  ? 383 GLU   C CB  1 
ATOM   4926 C CG  . GLU   C 1 169 ? 26.70309  -37.72900 -31.55157 1.000 71.85000  ? 383 GLU   C CG  1 
ATOM   4927 C CD  . GLU   C 1 169 ? 25.61395  -38.22022 -30.61384 1.000 72.26000  ? 383 GLU   C CD  1 
ATOM   4928 O OE1 . GLU   C 1 169 ? 24.42600  -37.94408 -30.91091 1.000 73.44000  ? 383 GLU   C OE1 1 
ATOM   4929 O OE2 . GLU   C 1 169 ? 25.95280  -38.89553 -29.60300 1.000 63.86000  ? 383 GLU   C OE2 1 
ATOM   4930 N N   . LYS   C 1 170 ? 23.98256  -37.19279 -35.24774 1.000 59.19000  ? 384 LYS   C N   1 
ATOM   4931 C CA  . LYS   C 1 170 ? 23.47473  -36.56641 -36.46162 1.000 60.20000  ? 384 LYS   C CA  1 
ATOM   4932 C C   . LYS   C 1 170 ? 24.15683  -35.22736 -36.73014 1.000 59.33000  ? 384 LYS   C C   1 
ATOM   4933 O O   . LYS   C 1 170 ? 24.40298  -34.87203 -37.89201 1.000 60.17000  ? 384 LYS   C O   1 
ATOM   4934 C CB  . LYS   C 1 170 ? 21.95773  -36.41537 -36.37575 1.000 56.69000  ? 384 LYS   C CB  1 
ATOM   4935 C CG  . LYS   C 1 170 ? 21.22574  -37.62417 -36.94720 1.000 64.18000  ? 384 LYS   C CG  1 
ATOM   4936 C CD  . LYS   C 1 170 ? 19.70675  -37.43809 -36.98233 1.000 71.82000  ? 384 LYS   C CD  1 
ATOM   4937 C CE  . LYS   C 1 170 ? 19.02779  -38.61584 -37.69775 1.000 77.91000  ? 384 LYS   C CE  1 
ATOM   4938 N NZ  . LYS   C 1 170 ? 20.04181  -39.56372 -38.29691 1.000 73.39000  ? 384 LYS   C NZ  1 
ATOM   4939 N N   . TYR   C 1 171 ? 24.52673  -34.49969 -35.67388 1.000 57.54000  ? 385 TYR   C N   1 
ATOM   4940 C CA  . TYR   C 1 171 ? 25.13081  -33.18366 -35.86343 1.000 58.13000  ? 385 TYR   C CA  1 
ATOM   4941 C C   . TYR   C 1 171 ? 26.53188  -33.28755 -36.45829 1.000 57.51000  ? 385 TYR   C C   1 
ATOM   4942 O O   . TYR   C 1 171 ? 27.01700  -32.33239 -37.08395 1.000 54.94000  ? 385 TYR   C O   1 
ATOM   4943 C CB  . TYR   C 1 171 ? 25.12969  -32.40605 -34.53220 1.000 57.98000  ? 385 TYR   C CB  1 
ATOM   4944 C CG  . TYR   C 1 171 ? 26.05954  -32.92441 -33.45824 1.000 64.49000  ? 385 TYR   C CG  1 
ATOM   4945 C CD1 . TYR   C 1 171 ? 27.42156  -32.62446 -33.49399 1.000 65.52000  ? 385 TYR   C CD1 1 
ATOM   4946 C CD2 . TYR   C 1 171 ? 25.58237  -33.67170 -32.38552 1.000 67.51000  ? 385 TYR   C CD2 1 
ATOM   4947 C CE1 . TYR   C 1 171 ? 28.29142  -33.08078 -32.53002 1.000 66.17000  ? 385 TYR   C CE1 1 
ATOM   4948 C CE2 . TYR   C 1 171 ? 26.45623  -34.12803 -31.38954 1.000 71.29000  ? 385 TYR   C CE2 1 
ATOM   4949 C CZ  . TYR   C 1 171 ? 27.81426  -33.82307 -31.48029 1.000 69.93000  ? 385 TYR   C CZ  1 
ATOM   4950 O OH  . TYR   C 1 171 ? 28.71613  -34.24739 -30.53131 1.000 73.32000  ? 385 TYR   C OH  1 
ATOM   4951 N N   . MET   C 1 172 ? 27.19381  -34.43264 -36.27854 1.000 56.60000  ? 386 MET   C N   1 
ATOM   4952 C CA  . MET   C 1 172 ? 28.45988  -34.66749 -36.96346 1.000 57.81000  ? 386 MET   C CA  1 
ATOM   4953 C C   . MET   C 1 172 ? 28.23005  -34.90405 -38.45556 1.000 55.63000  ? 386 MET   C C   1 
ATOM   4954 O O   . MET   C 1 172 ? 28.99917  -34.43183 -39.30433 1.000 50.19000  ? 386 MET   C O   1 
ATOM   4955 C CB  . MET   C 1 172 ? 29.18675  -35.85871 -36.32472 1.000 65.10000  ? 386 MET   C CB  1 
ATOM   4956 C CG  . MET   C 1 172 ? 29.85060  -35.57115 -34.95656 1.000 69.00000  ? 386 MET   C CG  1 
ATOM   4957 S SD  . MET   C 1 172 ? 30.24240  -36.99648 -33.88693 1.000 66.67000  ? 386 MET   C SD  1 
ATOM   4958 C CE  . MET   C 1 172 ? 31.89046  -37.37537 -34.52284 1.000 65.04000  ? 386 MET   C CE  1 
ATOM   4959 N N   . MET   C 1 173 ? 27.17205  -35.64290 -38.78790 1.000 59.47000  ? 387 MET   C N   1 
ATOM   4960 C CA  . MET   C 1 173 ? 26.76021  -35.76847 -40.17799 1.000 54.72000  ? 387 MET   C CA  1 
ATOM   4961 C C   . MET   C 1 173 ? 26.50635  -34.40528 -40.80162 1.000 51.53000  ? 387 MET   C C   1 
ATOM   4962 O O   . MET   C 1 173 ? 26.98150  -34.12498 -41.90748 1.000 53.98000  ? 387 MET   C O   1 
ATOM   4963 C CB  . MET   C 1 173 ? 25.52218  -36.65439 -40.25340 1.000 54.10000  ? 387 MET   C CB  1 
ATOM   4964 C CG  . MET   C 1 173 ? 25.79606  -38.04155 -39.76677 1.000 52.78000  ? 387 MET   C CG  1 
ATOM   4965 S SD  . MET   C 1 173 ? 24.29700  -39.01951 -39.67524 1.000 59.70000  ? 387 MET   C SD  1 
ATOM   4966 C CE  . MET   C 1 173 ? 24.79481  -40.30886 -38.53755 1.000 52.08000  ? 387 MET   C CE  1 
ATOM   4967 N N   . ASN   C 1 174 ? 25.80831  -33.52146 -40.08544 1.000 47.43000  ? 388 ASN   C N   1 
ATOM   4968 C CA  . ASN   C 1 174 ? 25.55943  -32.18229 -40.60008 1.000 50.84000  ? 388 ASN   C CA  1 
ATOM   4969 C C   . ASN   C 1 174 ? 26.85450  -31.41428 -40.86870 1.000 50.54000  ? 388 ASN   C C   1 
ATOM   4970 O O   . ASN   C 1 174 ? 26.92265  -30.63800 -41.82647 1.000 52.83000  ? 388 ASN   C O   1 
ATOM   4971 C CB  . ASN   C 1 174 ? 24.68135  -31.40254 -39.63196 1.000 49.09000  ? 388 ASN   C CB  1 
ATOM   4972 C CG  . ASN   C 1 174 ? 23.21336  -31.65641 -39.83921 1.000 56.57000  ? 388 ASN   C CG  1 
ATOM   4973 O OD1 . ASN   C 1 174 ? 22.78746  -32.23609 -40.84843 1.000 54.87000  ? 388 ASN   C OD1 1 
ATOM   4974 N ND2 . ASN   C 1 174 ? 22.41227  -31.19565 -38.87717 1.000 58.35000  ? 388 ASN   C ND2 1 
ATOM   4975 N N   . SER   C 1 175 ? 27.89439  -31.60357 -40.04263 1.000 52.61000  ? 389 SER   C N   1 
ATOM   4976 C CA  . SER   C 1 175 ? 29.14945  -30.88455 -40.29827 1.000 58.76000  ? 389 SER   C CA  1 
ATOM   4977 C C   . SER   C 1 175 ? 29.84058  -31.38021 -41.56033 1.000 52.34000  ? 389 SER   C C   1 
ATOM   4978 O O   . SER   C 1 175 ? 30.46971  -30.59803 -42.27803 1.000 55.68000  ? 389 SER   C O   1 
ATOM   4979 C CB  . SER   C 1 175 ? 30.10631  -30.97194 -39.11218 1.000 49.59000  ? 389 SER   C CB  1 
ATOM   4980 O OG  . SER   C 1 175 ? 29.55421  -30.27624 -38.01504 1.000 59.90000  ? 389 SER   C OG  1 
ATOM   4981 N N   . VAL   C 1 176 ? 29.73956  -32.67412 -41.85072 1.000 49.38000  ? 390 VAL   C N   1 
ATOM   4982 C CA  . VAL   C 1 176 ? 30.25369  -33.16477 -43.12181 1.000 54.55000  ? 390 VAL   C CA  1 
ATOM   4983 C C   . VAL   C 1 176 ? 29.45885  -32.57940 -44.28273 1.000 57.82000  ? 390 VAL   C C   1 
ATOM   4984 O O   . VAL   C 1 176 ? 30.03300  -32.13813 -45.29353 1.000 51.12000  ? 390 VAL   C O   1 
ATOM   4985 C CB  . VAL   C 1 176 ? 30.22962  -34.69977 -43.13726 1.000 52.52000  ? 390 VAL   C CB  1 
ATOM   4986 C CG1 . VAL   C 1 176 ? 30.70576  -35.21239 -44.48635 1.000 52.92000  ? 390 VAL   C CG1 1 
ATOM   4987 C CG2 . VAL   C 1 176 ? 31.08246  -35.22914 -41.99231 1.000 52.24000  ? 390 VAL   C CG2 1 
ATOM   4988 N N   . LEU   C 1 177 ? 28.12684  -32.54537 -44.14288 1.000 53.88000  ? 391 LEU   C N   1 
ATOM   4989 C CA  . LEU   C 1 177 ? 27.26399  -32.19001 -45.26388 1.000 52.60000  ? 391 LEU   C CA  1 
ATOM   4990 C C   . LEU   C 1 177 ? 27.36110  -30.70991 -45.62043 1.000 55.57000  ? 391 LEU   C C   1 
ATOM   4991 O O   . LEU   C 1 177 ? 27.10026  -30.33456 -46.77036 1.000 59.02000  ? 391 LEU   C O   1 
ATOM   4992 C CB  . LEU   C 1 177 ? 25.82393  -32.57203 -44.94116 1.000 53.37000  ? 391 LEU   C CB  1 
ATOM   4993 C CG  . LEU   C 1 177 ? 25.58986  -34.08505 -44.86264 1.000 52.58000  ? 391 LEU   C CG  1 
ATOM   4994 C CD1 . LEU   C 1 177 ? 24.10986  -34.34195 -44.96989 1.000 51.18000  ? 391 LEU   C CD1 1 
ATOM   4995 C CD2 . LEU   C 1 177 ? 26.35195  -34.85077 -45.94377 1.000 45.11000  ? 391 LEU   C CD2 1 
ATOM   4996 N N   . GLU   C 1 178 ? 27.72803  -29.85220 -44.66314 1.000 59.40000  ? 392 GLU   C N   1 
ATOM   4997 C CA  . GLU   C 1 178 ? 27.99713  -28.46411 -45.01970 1.000 60.18000  ? 392 GLU   C CA  1 
ATOM   4998 C C   . GLU   C 1 178 ? 29.04527  -28.38684 -46.11255 1.000 59.98000  ? 392 GLU   C C   1 
ATOM   4999 O O   . GLU   C 1 178 ? 29.02441  -27.46960 -46.94228 1.000 63.42000  ? 392 GLU   C O   1 
ATOM   5000 C CB  . GLU   C 1 178 ? 28.47902  -27.67749 -43.81141 1.000 57.64000  ? 392 GLU   C CB  1 
ATOM   5001 C CG  . GLU   C 1 178 ? 27.58988  -27.79379 -42.62355 1.000 59.09000  ? 392 GLU   C CG  1 
ATOM   5002 C CD  . GLU   C 1 178 ? 28.16677  -27.06317 -41.44327 1.000 63.03000  ? 392 GLU   C CD  1 
ATOM   5003 O OE1 . GLU   C 1 178 ? 29.18282  -26.35716 -41.63494 1.000 63.60000  ? 392 GLU   C OE1 1 
ATOM   5004 O OE2 . GLU   C 1 178 ? 27.62663  -27.19847 -40.32637 1.000 68.38000  ? 392 GLU   C OE2 1 
ATOM   5005 N N   . ASN   C 1 179 ? 29.95423  -29.34787 -46.14372 1.000 56.21000  ? 393 ASN   C N   1 
ATOM   5006 C CA  . ASN   C 1 179 ? 31.04234  -29.34464 -47.09959 1.000 57.60000  ? 393 ASN   C CA  1 
ATOM   5007 C C   . ASN   C 1 179 ? 30.73045  -30.16526 -48.34687 1.000 55.57000  ? 393 ASN   C C   1 
ATOM   5008 O O   . ASN   C 1 179 ? 31.64854  -30.45007 -49.13184 1.000 58.69000  ? 393 ASN   C O   1 
ATOM   5009 C CB  . ASN   C 1 179 ? 32.30224  -29.86090 -46.41159 1.000 64.39000  ? 393 ASN   C CB  1 
ATOM   5010 C CG  . ASN   C 1 179 ? 32.54010  -29.18631 -45.05637 1.000 63.71000  ? 393 ASN   C CG  1 
ATOM   5011 O OD1 . ASN   C 1 179 ? 32.16213  -28.02236 -44.83907 1.000 63.82000  ? 393 ASN   C OD1 1 
ATOM   5012 N ND2 . ASN   C 1 179 ? 33.12696  -29.93061 -44.13051 1.000 55.12000  ? 393 ASN   C ND2 1 
ATOM   5013 N N   . PHE   C 1 180 ? 29.46046  -30.53515 -48.54413 1.000 50.10000  ? 394 PHE   C N   1 
ATOM   5014 C CA  . PHE   C 1 180 ? 29.03254  -31.45582 -49.59045 1.000 51.24000  ? 394 PHE   C CA  1 
ATOM   5015 C C   . PHE   C 1 180 ? 27.88467  -30.83954 -50.37241 1.000 51.05000  ? 394 PHE   C C   1 
ATOM   5016 O O   . PHE   C 1 180 ? 26.87961  -30.44067 -49.77441 1.000 49.49000  ? 394 PHE   C O   1 
ATOM   5017 C CB  . PHE   C 1 180 ? 28.57941  -32.79397 -49.00390 1.000 49.77000  ? 394 PHE   C CB  1 
ATOM   5018 C CG  . PHE   C 1 180 ? 27.98349  -33.72965 -50.02124 1.000 50.17000  ? 394 PHE   C CG  1 
ATOM   5019 C CD1 . PHE   C 1 180 ? 28.79355  -34.50545 -50.82237 1.000 52.60000  ? 394 PHE   C CD1 1 
ATOM   5020 C CD2 . PHE   C 1 180 ? 26.61051  -33.81953 -50.18644 1.000 52.15000  ? 394 PHE   C CD2 1 
ATOM   5021 C CE1 . PHE   C 1 180 ? 28.25263  -35.36315 -51.76669 1.000 50.68000  ? 394 PHE   C CE1 1 
ATOM   5022 C CE2 . PHE   C 1 180 ? 26.06958  -34.67323 -51.12475 1.000 49.69000  ? 394 PHE   C CE2 1 
ATOM   5023 C CZ  . PHE   C 1 180 ? 26.90564  -35.44904 -51.91488 1.000 50.13000  ? 394 PHE   C CZ  1 
ATOM   5024 N N   . THR   C 1 181 ? 28.02483  -30.77815 -51.70337 1.000 44.24000  ? 395 THR   C N   1 
ATOM   5025 C CA  . THR   C 1 181 ? 26.95996  -30.24686 -52.55435 1.000 47.02000  ? 395 THR   C CA  1 
ATOM   5026 C C   . THR   C 1 181 ? 26.95509  -30.95646 -53.90656 1.000 47.79000  ? 395 THR   C C   1 
ATOM   5027 O O   . THR   C 1 181 ? 27.92811  -31.59839 -54.30663 1.000 43.70000  ? 395 THR   C O   1 
ATOM   5028 C CB  . THR   C 1 181 ? 27.07606  -28.73678 -52.82889 1.000 45.37000  ? 395 THR   C CB  1 
ATOM   5029 O OG1 . THR   C 1 181 ? 28.30815  -28.45964 -53.51266 1.000 50.90000  ? 395 THR   C OG1 1 
ATOM   5030 C CG2 . THR   C 1 181 ? 26.97294  -27.89516 -51.53566 1.000 39.35000  ? 395 THR   C CG2 1 
ATOM   5031 N N   . ILE   C 1 182 ? 25.84018  -30.81620 -54.61765 1.000 46.44000  ? 396 ILE   C N   1 
ATOM   5032 C CA  . ILE   C 1 182 ? 25.73632  -31.30080 -55.98280 1.000 45.44000  ? 396 ILE   C CA  1 
ATOM   5033 C C   . ILE   C 1 182 ? 25.20348  -30.18052 -56.84854 1.000 45.57000  ? 396 ILE   C C   1 
ATOM   5034 O O   . ILE   C 1 182 ? 24.28746  -29.45459 -56.44844 1.000 40.64000  ? 396 ILE   C O   1 
ATOM   5035 C CB  . ILE   C 1 182 ? 24.84228  -32.54672 -56.11528 1.000 41.98000  ? 396 ILE   C CB  1 
ATOM   5036 C CG1 . ILE   C 1 182 ? 25.55915  -33.74592 -55.51754 1.000 41.65000  ? 396 ILE   C CG1 1 
ATOM   5037 C CG2 . ILE   C 1 182 ? 24.53344  -32.81527 -57.57739 1.000 37.58000  ? 396 ILE   C CG2 1 
ATOM   5038 C CD1 . ILE   C 1 182 ? 24.62805  -34.74003 -55.00994 1.000 43.98000  ? 396 ILE   C CD1 1 
ATOM   5039 N N   . LEU   C 1 183 ? 25.81262  -30.02820 -58.02242 1.000 45.27000  ? 397 LEU   C N   1 
ATOM   5040 C CA  . LEU   C 1 183 ? 25.39179  -29.09188 -59.05120 1.000 44.96000  ? 397 LEU   C CA  1 
ATOM   5041 C C   . LEU   C 1 183 ? 25.00490  -29.88750 -60.28048 1.000 45.03000  ? 397 LEU   C C   1 
ATOM   5042 O O   . LEU   C 1 183 ? 25.84494  -30.59537 -60.84958 1.000 50.51000  ? 397 LEU   C O   1 
ATOM   5043 C CB  . LEU   C 1 183 ? 26.51388  -28.12883 -59.40478 1.000 48.39000  ? 397 LEU   C CB  1 
ATOM   5044 C CG  . LEU   C 1 183 ? 26.07703  -26.92457 -60.21448 1.000 47.27000  ? 397 LEU   C CG  1 
ATOM   5045 C CD1 . LEU   C 1 183 ? 25.05797  -26.09976 -59.42236 1.000 35.06000  ? 397 LEU   C CD1 1 
ATOM   5046 C CD2 . LEU   C 1 183 ? 27.35310  -26.13254 -60.52509 1.000 37.08000  ? 397 LEU   C CD2 1 
ATOM   5047 N N   . GLN   C 1 184 ? 23.74696  -29.76732 -60.69359 1.000 45.48000  ? 398 GLN   C N   1 
ATOM   5048 C CA  . GLN   C 1 184 ? 23.27508  -30.37194 -61.93483 1.000 49.82000  ? 398 GLN   C CA  1 
ATOM   5049 C C   . GLN   C 1 184 ? 23.05025  -29.29462 -62.97954 1.000 46.21000  ? 398 GLN   C C   1 
ATOM   5050 O O   . GLN   C 1 184 ? 22.28227  -28.35465 -62.75336 1.000 46.45000  ? 398 GLN   C O   1 
ATOM   5051 C CB  . GLN   C 1 184 ? 22.00702  -31.18294 -61.72022 1.000 47.46000  ? 398 GLN   C CB  1 
ATOM   5052 C CG  . GLN   C 1 184 ? 21.72411  -32.07659 -62.88851 1.000 48.54000  ? 398 GLN   C CG  1 
ATOM   5053 C CD  . GLN   C 1 184 ? 20.47305  -32.88659 -62.68090 1.000 57.98000  ? 398 GLN   C CD  1 
ATOM   5054 O OE1 . GLN   C 1 184 ? 19.36010  -32.42047 -62.93090 1.000 56.38000  ? 398 GLN   C OE1 1 
ATOM   5055 N NE2 . GLN   C 1 184 ? 20.64994  -34.12773 -62.23224 1.000 64.79000  ? 398 GLN   C NE2 1 
ATOM   5056 N N   . VAL   C 1 185 ? 23.74538  -29.41532 -64.10549 1.000 46.66000  ? 399 VAL   C N   1 
ATOM   5057 C CA  . VAL   C 1 185 ? 23.59256  -28.48599 -65.21924 1.000 50.28000  ? 399 VAL   C CA  1 
ATOM   5058 C C   . VAL   C 1 185 ? 23.07267  -29.27162 -66.42053 1.000 45.60000  ? 399 VAL   C C   1 
ATOM   5059 O O   . VAL   C 1 185 ? 23.69868  -30.24852 -66.85074 1.000 46.30000  ? 399 VAL   C O   1 
ATOM   5060 C CB  . VAL   C 1 185 ? 24.90863  -27.75596 -65.53986 1.000 42.34000  ? 399 VAL   C CB  1 
ATOM   5061 C CG1 . VAL   C 1 185 ? 24.70682  -26.79261 -66.70761 1.000 36.62000  ? 399 VAL   C CG1 1 
ATOM   5062 C CG2 . VAL   C 1 185 ? 25.40952  -27.01734 -64.30759 1.000 39.29000  ? 399 VAL   C CG2 1 
ATOM   5063 N N   . VAL   C 1 186 ? 21.91875  -28.86741 -66.94055 1.000 46.12000  ? 400 VAL   C N   1 
ATOM   5064 C CA  . VAL   C 1 186 ? 21.30386  -29.48804 -68.11181 1.000 50.88000  ? 400 VAL   C CA  1 
ATOM   5065 C C   . VAL   C 1 186 ? 21.39405  -28.51970 -69.29351 1.000 50.19000  ? 400 VAL   C C   1 
ATOM   5066 O O   . VAL   C 1 186 ? 20.92509  -27.37770 -69.21523 1.000 52.39000  ? 400 VAL   C O   1 
ATOM   5067 C CB  . VAL   C 1 186 ? 19.84781  -29.89905 -67.83210 1.000 46.54000  ? 400 VAL   C CB  1 
ATOM   5068 C CG1 . VAL   C 1 186 ? 19.31691  -30.74769 -68.98041 1.000 50.43000  ? 400 VAL   C CG1 1 
ATOM   5069 C CG2 . VAL   C 1 186 ? 19.76162  -30.64943 -66.52533 1.000 47.06000  ? 400 VAL   C CG2 1 
ATOM   5070 N N   . THR   C 1 187 ? 21.99216  -28.97140 -70.38657 1.000 55.24000  ? 401 THR   C N   1 
ATOM   5071 C CA  . THR   C 1 187 ? 22.16334  -28.12907 -71.55930 1.000 56.14000  ? 401 THR   C CA  1 
ATOM   5072 C C   . THR   C 1 187 ? 21.56645  -28.81168 -72.77958 1.000 56.00000  ? 401 THR   C C   1 
ATOM   5073 O O   . THR   C 1 187 ? 21.46440  -30.03966 -72.82795 1.000 55.23000  ? 401 THR   C O   1 
ATOM   5074 C CB  . THR   C 1 187 ? 23.65038  -27.82106 -71.82304 1.000 58.22000  ? 401 THR   C CB  1 
ATOM   5075 O OG1 . THR   C 1 187 ? 24.43130  -29.00016 -71.59429 1.000 57.46000  ? 401 THR   C OG1 1 
ATOM   5076 C CG2 . THR   C 1 187 ? 24.15632  -26.70735 -70.89765 1.000 54.92000  ? 401 THR   C CG2 1 
ATOM   5077 N N   . SER   C 1 188 ? 21.16561  -27.99838 -73.75939 1.000 62.31000  ? 402 SER   C N   1 
ATOM   5078 C CA  . SER   C 1 188 ? 20.88675  -28.49697 -75.10757 1.000 62.36000  ? 402 SER   C CA  1 
ATOM   5079 C C   . SER   C 1 188 ? 22.19480  -28.93784 -75.74554 1.000 60.27000  ? 402 SER   C C   1 
ATOM   5080 O O   . SER   C 1 188 ? 23.12186  -28.13585 -75.86019 1.000 65.93000  ? 402 SER   C O   1 
ATOM   5081 C CB  . SER   C 1 188 ? 20.22190  -27.40969 -75.94833 1.000 61.71000  ? 402 SER   C CB  1 
ATOM   5082 O OG  . SER   C 1 188 ? 19.79003  -27.91630 -77.20753 1.000 74.16000  ? 402 SER   C OG  1 
ATOM   5083 N N   . ARG   C 1 189 ? 22.28479  -30.20873 -76.14790 1.000 60.79000  ? 403 ARG   C N   1 
ATOM   5084 C CA  . ARG   C 1 189 ? 23.59381  -30.76669 -76.49591 1.000 69.70000  ? 403 ARG   C CA  1 
ATOM   5085 C C   . ARG   C 1 189 ? 24.25798  -29.99439 -77.62860 1.000 73.77000  ? 403 ARG   C C   1 
ATOM   5086 O O   . ARG   C 1 189 ? 25.43399  -29.62347 -77.53435 1.000 77.91000  ? 403 ARG   C O   1 
ATOM   5087 C CB  . ARG   C 1 189 ? 23.49179  -32.24357 -76.87035 1.000 68.24000  ? 403 ARG   C CB  1 
ATOM   5088 C CG  . ARG   C 1 189 ? 24.85874  -32.91067 -76.76738 1.000 72.19000  ? 403 ARG   C CG  1 
ATOM   5089 C CD  . ARG   C 1 189 ? 25.36188  -33.44730 -78.08048 1.000 73.65000  ? 403 ARG   C CD  1 
ATOM   5090 N NE  . ARG   C 1 189 ? 24.37791  -34.33708 -78.67786 1.000 78.21000  ? 403 ARG   C NE  1 
ATOM   5091 C CZ  . ARG   C 1 189 ? 24.51186  -35.65507 -78.75623 1.000 79.27000  ? 403 ARG   C CZ  1 
ATOM   5092 N NH1 . ARG   C 1 189 ? 25.58777  -36.27226 -78.28328 1.000 76.67000  ? 403 ARG   C NH1 1 
ATOM   5093 N NH2 . ARG   C 1 189 ? 23.54089  -36.37586 -79.31656 1.000 73.66000  ? 403 ARG   C NH2 1 
ATOM   5094 N N   . ASP   C 1 190 ? 23.53612  -29.75603 -78.71762 1.000 72.59000  ? 404 ASP   C N   1 
ATOM   5095 C CA  . ASP   C 1 190 ? 24.14129  -29.01274 -79.81933 1.000 82.19000  ? 404 ASP   C CA  1 
ATOM   5096 C C   . ASP   C 1 190 ? 24.20432  -27.52484 -79.48888 1.000 77.93000  ? 404 ASP   C C   1 
ATOM   5097 O O   . ASP   C 1 190 ? 25.26036  -26.88685 -79.61457 1.000 77.58000  ? 404 ASP   C O   1 
ATOM   5098 C CB  . ASP   C 1 190 ? 23.35143  -29.26733 -81.10650 1.000 89.62000  ? 404 ASP   C CB  1 
ATOM   5099 C CG  . ASP   C 1 190 ? 23.09740  -30.75624 -81.34996 1.000 91.57000  ? 404 ASP   C CG  1 
ATOM   5100 O OD1 . ASP   C 1 190 ? 23.79528  -31.58346 -80.71412 1.000 88.38000  ? 404 ASP   C OD1 1 
ATOM   5101 O OD2 . ASP   C 1 190 ? 22.20148  -31.09496 -82.16017 1.000 88.87000  ? 404 ASP   C OD2 1 
ATOM   5102 N N   . SER   C 1 191 ? 23.08329  -26.97693 -79.01286 1.000 76.52000  ? 405 SER   C N   1 
ATOM   5103 C CA  . SER   C 1 191 ? 22.94732  -25.54599 -78.75845 1.000 75.61000  ? 405 SER   C CA  1 
ATOM   5104 C C   . SER   C 1 191 ? 23.92622  -25.03935 -77.70219 1.000 77.95000  ? 405 SER   C C   1 
ATOM   5105 O O   . SER   C 1 191 ? 24.24427  -23.84537 -77.68380 1.000 83.15000  ? 405 SER   C O   1 
ATOM   5106 C CB  . SER   C 1 191 ? 21.50129  -25.25605 -78.33854 1.000 75.63000  ? 405 SER   C CB  1 
ATOM   5107 O OG  . SER   C 1 191 ? 21.33628  -23.94619 -77.82718 1.000 77.98000  ? 405 SER   C OG  1 
ATOM   5108 N N   . GLN   C 1 192 ? 24.40707  -25.91363 -76.81739 1.000 75.65000  ? 406 GLN   C N   1 
ATOM   5109 C CA  . GLN   C 1 192 ? 25.20095  -25.56501 -75.64319 1.000 70.88000  ? 406 GLN   C CA  1 
ATOM   5110 C C   . GLN   C 1 192 ? 24.43787  -24.68427 -74.65002 1.000 67.84000  ? 406 GLN   C C   1 
ATOM   5111 O O   . GLN   C 1 192 ? 25.01676  -24.28359 -73.62983 1.000 65.16000  ? 406 GLN   C O   1 
ATOM   5112 C CB  . GLN   C 1 192 ? 26.52902  -24.88796 -76.01983 1.000 73.22000  ? 406 GLN   C CB  1 
ATOM   5113 C CG  . GLN   C 1 192 ? 27.53607  -25.81980 -76.71998 1.000 79.50000  ? 406 GLN   C CG  1 
ATOM   5114 C CD  . GLN   C 1 192 ? 28.90898  -25.89607 -76.01084 1.000 80.01000  ? 406 GLN   C CD  1 
ATOM   5115 O OE1 . GLN   C 1 192 ? 29.02582  -26.45140 -74.90999 1.000 81.32000  ? 406 GLN   C OE1 1 
ATOM   5116 N NE2 . GLN   C 1 192 ? 29.95408  -25.37793 -76.66556 1.000 76.34000  ? 406 GLN   C NE2 1 
ATOM   5117 N N   . GLU   C 1 193 ? 23.15891  -24.39313 -74.89909 1.000 65.36000  ? 407 GLU   C N   1 
ATOM   5118 C CA  . GLU   C 1 193 ? 22.36785  -23.51035 -74.05393 1.000 67.16000  ? 407 GLU   C CA  1 
ATOM   5119 C C   . GLU   C 1 193 ? 22.04266  -24.16172 -72.71116 1.000 64.68000  ? 407 GLU   C C   1 
ATOM   5120 O O   . GLU   C 1 193 ? 21.86759  -25.37775 -72.60353 1.000 58.91000  ? 407 GLU   C O   1 
ATOM   5121 C CB  . GLU   C 1 193 ? 21.06296  -23.11808 -74.76797 1.000 70.01000  ? 407 GLU   C CB  1 
ATOM   5122 C CG  . GLU   C 1 193 ? 20.28793  -21.94723 -74.12672 1.000 71.32000  ? 407 GLU   C CG  1 
ATOM   5123 C CD  . GLU   C 1 193 ? 18.76895  -22.05611 -74.29693 1.000 77.65000  ? 407 GLU   C CD  1 
ATOM   5124 O OE1 . GLU   C 1 193 ? 18.31103  -22.71781 -75.25318 1.000 77.22000  ? 407 GLU   C OE1 1 
ATOM   5125 O OE2 . GLU   C 1 193 ? 18.02188  -21.45831 -73.48785 1.000 77.14000  ? 407 GLU   C OE2 1 
ATOM   5126 N N   . THR   C 1 194 ? 21.92858  -23.32602 -71.68793 1.000 58.71000  ? 408 THR   C N   1 
ATOM   5127 C CA  . THR   C 1 194 ? 21.60939  -23.79740 -70.34810 1.000 57.40000  ? 408 THR   C CA  1 
ATOM   5128 C C   . THR   C 1 194 ? 20.09837  -24.01436 -70.23335 1.000 54.99000  ? 408 THR   C C   1 
ATOM   5129 O O   . THR   C 1 194 ? 19.31342  -23.06330 -70.32416 1.000 51.72000  ? 408 THR   C O   1 
ATOM   5130 C CB  . THR   C 1 194 ? 22.12732  -22.78972 -69.32374 1.000 54.67000  ? 408 THR   C CB  1 
ATOM   5131 O OG1 . THR   C 1 194 ? 23.55334  -22.65474 -69.46553 1.000 52.86000  ? 408 THR   C OG1 1 
ATOM   5132 C CG2 . THR   C 1 194 ? 21.78613  -23.23511 -67.92792 1.000 50.71000  ? 408 THR   C CG2 1 
ATOM   5133 N N   . LEU   C 1 195 ? 19.68029  -25.26840 -70.04776 1.000 50.60000  ? 409 LEU   C N   1 
ATOM   5134 C CA  . LEU   C 1 195 ? 18.25926  -25.53838 -69.88101 1.000 44.06000  ? 409 LEU   C CA  1 
ATOM   5135 C C   . LEU   C 1 195 ? 17.82608  -25.47479 -68.43005 1.000 49.15000  ? 409 LEU   C C   1 
ATOM   5136 O O   . LEU   C 1 195 ? 16.72507  -25.00282 -68.13804 1.000 48.02000  ? 409 LEU   C O   1 
ATOM   5137 C CB  . LEU   C 1 195 ? 17.88626  -26.90619 -70.46046 1.000 50.11000  ? 409 LEU   C CB  1 
ATOM   5138 C CG  . LEU   C 1 195 ? 18.13143  -27.14877 -71.95850 1.000 56.27000  ? 409 LEU   C CG  1 
ATOM   5139 C CD1 . LEU   C 1 195 ? 17.74042  -28.56562 -72.38396 1.000 53.90000  ? 409 LEU   C CD1 1 
ATOM   5140 C CD2 . LEU   C 1 195 ? 17.39558  -26.12349 -72.78929 1.000 57.01000  ? 409 LEU   C CD2 1 
ATOM   5141 N N   . LEU   C 1 196 ? 18.66395  -25.94409 -67.50808 1.000 53.28000  ? 410 LEU   C N   1 
ATOM   5142 C CA  . LEU   C 1 196 ? 18.26278  -26.07148 -66.11617 1.000 48.82000  ? 410 LEU   C CA  1 
ATOM   5143 C C   . LEU   C 1 196 ? 19.50367  -26.25879 -65.26808 1.000 52.16000  ? 410 LEU   C C   1 
ATOM   5144 O O   . LEU   C 1 196 ? 20.47169  -26.90571 -65.68415 1.000 45.67000  ? 410 LEU   C O   1 
ATOM   5145 C CB  . LEU   C 1 196 ? 17.30670  -27.24950 -65.91163 1.000 48.24000  ? 410 LEU   C CB  1 
ATOM   5146 C CG  . LEU   C 1 196 ? 16.50654  -27.32684 -64.61975 1.000 46.33000  ? 410 LEU   C CG  1 
ATOM   5147 C CD1 . LEU   C 1 196 ? 15.39659  -26.28979 -64.62258 1.000 51.77000  ? 410 LEU   C CD1 1 
ATOM   5148 C CD2 . LEU   C 1 196 ? 15.93446  -28.73085 -64.50623 1.000 45.61000  ? 410 LEU   C CD2 1 
ATOM   5149 N N   . VAL   C 1 197 ? 19.45755  -25.67714 -64.06991 1.000 49.40000  ? 411 VAL   C N   1 
ATOM   5150 C CA  . VAL   C 1 197 ? 20.55744  -25.72647 -63.12179 1.000 44.40000  ? 411 VAL   C CA  1 
ATOM   5151 C C   . VAL   C 1 197 ? 19.95626  -25.91284 -61.73692 1.000 45.65000  ? 411 VAL   C C   1 
ATOM   5152 O O   . VAL   C 1 197 ? 19.14124  -25.09394 -61.28978 1.000 42.79000  ? 411 VAL   C O   1 
ATOM   5153 C CB  . VAL   C 1 197 ? 21.42550  -24.45749 -63.17532 1.000 46.61000  ? 411 VAL   C CB  1 
ATOM   5154 C CG1 . VAL   C 1 197 ? 22.52937  -24.50286 -62.09720 1.000 39.93000  ? 411 VAL   C CG1 1 
ATOM   5155 C CG2 . VAL   C 1 197 ? 22.01168  -24.27811 -64.57719 1.000 43.52000  ? 411 VAL   C CG2 1 
ATOM   5156 N N   . ILE   C 1 198 ? 20.33013  -26.99506 -61.06519 1.000 41.39000  ? 412 ILE   C N   1 
ATOM   5157 C CA  . ILE   C 1 198 ? 19.88695  -27.23544 -59.70432 1.000 46.90000  ? 412 ILE   C CA  1 
ATOM   5158 C C   . ILE   C 1 198 ? 21.12685  -27.33175 -58.83519 1.000 40.48000  ? 412 ILE   C C   1 
ATOM   5159 O O   . ILE   C 1 198 ? 21.93282  -28.25273 -59.01237 1.000 41.98000  ? 412 ILE   C O   1 
ATOM   5160 C CB  . ILE   C 1 198 ? 19.02988  -28.49944 -59.56979 1.000 46.37000  ? 412 ILE   C CB  1 
ATOM   5161 C CG1 . ILE   C 1 198 ? 18.04401  -28.62305 -60.73394 1.000 46.42000  ? 412 ILE   C CG1 1 
ATOM   5162 C CG2 . ILE   C 1 198 ? 18.27172  -28.45979 -58.25587 1.000 45.04000  ? 412 ILE   C CG2 1 
ATOM   5163 C CD1 . ILE   C 1 198 ? 16.94694  -29.68307 -60.51039 1.000 42.98000  ? 412 ILE   C CD1 1 
ATOM   5164 N N   . ALA   C 1 199 ? 21.28278  -26.37503 -57.90790 1.000 38.17000  ? 413 ALA   C N   1 
ATOM   5165 C CA  . ALA   C 1 199 ? 22.23264  -26.46640 -56.79681 1.000 44.63000  ? 413 ALA   C CA  1 
ATOM   5166 C C   . ALA   C 1 199 ? 21.58646  -27.17771 -55.60709 1.000 41.34000  ? 413 ALA   C C   1 
ATOM   5167 O O   . ALA   C 1 199 ? 20.52343  -26.76480 -55.13610 1.000 42.17000  ? 413 ALA   C O   1 
ATOM   5168 C CB  . ALA   C 1 199 ? 22.71165  -25.07354 -56.38234 1.000 37.93000  ? 413 ALA   C CB  1 
ATOM   5169 N N   . PHE   C 1 200 ? 22.22736  -28.24788 -55.13033 1.000 43.29000  ? 414 PHE   C N   1 
ATOM   5170 C CA  . PHE   C 1 200 ? 21.71519  -29.07118 -54.02963 1.000 45.76000  ? 414 PHE   C CA  1 
ATOM   5171 C C   . PHE   C 1 200 ? 22.58905  -28.88659 -52.79347 1.000 46.23000  ? 414 PHE   C C   1 
ATOM   5172 O O   . PHE   C 1 200 ? 23.79804  -29.13963 -52.83840 1.000 43.75000  ? 414 PHE   C O   1 
ATOM   5173 C CB  . PHE   C 1 200 ? 21.68816  -30.55508 -54.39307 1.000 37.95000  ? 414 PHE   C CB  1 
ATOM   5174 C CG  . PHE   C 1 200 ? 20.80529  -30.89169 -55.57328 1.000 48.78000  ? 414 PHE   C CG  1 
ATOM   5175 C CD1 . PHE   C 1 200 ? 21.29245  -30.78933 -56.87319 1.000 47.98000  ? 414 PHE   C CD1 1 
ATOM   5176 C CD2 . PHE   C 1 200 ? 19.52724  -31.38769 -55.38558 1.000 49.75000  ? 414 PHE   C CD2 1 
ATOM   5177 C CE1 . PHE   C 1 200 ? 20.51556  -31.11798 -57.94338 1.000 46.14000  ? 414 PHE   C CE1 1 
ATOM   5178 C CE2 . PHE   C 1 200 ? 18.73136  -31.72933 -56.47577 1.000 46.72000  ? 414 PHE   C CE2 1 
ATOM   5179 C CZ  . PHE   C 1 200 ? 19.22552  -31.59398 -57.74067 1.000 48.27000  ? 414 PHE   C CZ  1 
ATOM   5180 N N   . VAL   C 1 201 ? 21.97793  -28.46788 -51.68842 1.000 48.29000  ? 415 VAL   C N   1 
ATOM   5181 C CA  . VAL   C 1 201 ? 22.66778  -28.46529 -50.40434 1.000 47.08000  ? 415 VAL   C CA  1 
ATOM   5182 C C   . VAL   C 1 201 ? 21.95663  -29.48252 -49.51272 1.000 47.09000  ? 415 VAL   C C   1 
ATOM   5183 O O   . VAL   C 1 201 ? 20.82164  -29.88039 -49.78198 1.000 48.22000  ? 415 VAL   C O   1 
ATOM   5184 C CB  . VAL   C 1 201 ? 22.68877  -27.07348 -49.75493 1.000 40.02000  ? 415 VAL   C CB  1 
ATOM   5185 C CG1 . VAL   C 1 201 ? 23.39392  -26.06724 -50.67355 1.000 37.63000  ? 415 VAL   C CG1 1 
ATOM   5186 C CG2 . VAL   C 1 201 ? 21.29574  -26.64853 -49.37197 1.000 41.61000  ? 415 VAL   C CG2 1 
ATOM   5187 N N   . PHE   C 1 202 ? 22.70149  -30.02583 -48.56179 1.000 49.66000  ? 416 PHE   C N   1 
ATOM   5188 C CA  . PHE   C 1 202 ? 22.16834  -31.13104 -47.77818 1.000 43.32000  ? 416 PHE   C CA  1 
ATOM   5189 C C   . PHE   C 1 202 ? 22.33316  -31.13048 -46.28616 1.000 51.22000  ? 416 PHE   C C   1 
ATOM   5190 O O   . PHE   C 1 202 ? 23.33412  -30.67568 -45.76791 1.000 56.96000  ? 416 PHE   C O   1 
ATOM   5191 C CB  . PHE   C 1 202 ? 22.87134  -32.40493 -48.24547 1.000 44.95000  ? 416 PHE   C CB  1 
ATOM   5192 C CG  . PHE   C 1 202 ? 22.75050  -32.68150 -49.71257 1.000 49.96000  ? 416 PHE   C CG  1 
ATOM   5193 C CD1 . PHE   C 1 202 ? 23.61064  -32.08627 -50.61629 1.000 48.29000  ? 416 PHE   C CD1 1 
ATOM   5194 C CD2 . PHE   C 1 202 ? 21.80752  -33.57132 -50.18094 1.000 43.43000  ? 416 PHE   C CD2 1 
ATOM   5195 C CE1 . PHE   C 1 202 ? 23.51379  -32.34887 -51.95938 1.000 47.76000  ? 416 PHE   C CE1 1 
ATOM   5196 C CE2 . PHE   C 1 202 ? 21.70467  -33.83892 -51.52503 1.000 45.09000  ? 416 PHE   C CE2 1 
ATOM   5197 C CZ  . PHE   C 1 202 ? 22.55880  -33.22669 -52.41575 1.000 46.87000  ? 416 PHE   C CZ  1 
ATOM   5198 N N   . GLU   C 1 203 ? 21.33206  -31.63864 -45.59243 1.000 41.45000  ? 417 GLU   C N   1 
ATOM   5199 C CA  . GLU   C 1 203 ? 21.42788  -31.81406 -44.16747 1.000 51.29000  ? 417 GLU   C CA  1 
ATOM   5200 C C   . GLU   C 1 203 ? 20.80278  -33.15412 -43.84694 1.000 52.99000  ? 417 GLU   C C   1 
ATOM   5201 O O   . GLU   C 1 203 ? 20.02385  -33.65286 -44.62518 1.000 50.22000  ? 417 GLU   C O   1 
ATOM   5202 C CB  . GLU   C 1 203 ? 20.70984  -30.71425 -43.41723 1.000 52.95000  ? 417 GLU   C CB  1 
ATOM   5203 C CG  . GLU   C 1 203 ? 21.49187  -29.43934 -43.22377 1.000 52.61000  ? 417 GLU   C CG  1 
ATOM   5204 C CD  . GLU   C 1 203 ? 20.87778  -28.57263 -42.14859 1.000 55.06000  ? 417 GLU   C CD  1 
ATOM   5205 O OE1 . GLU   C 1 203 ? 20.19065  -29.12285 -41.26783 1.000 54.10000  ? 417 GLU   C OE1 1 
ATOM   5206 O OE2 . GLU   C 1 203 ? 21.08184  -27.34563 -42.17920 1.000 63.26000  ? 417 GLU   C OE2 1 
ATOM   5207 N N   . VAL   C 1 204 ? 21.21162  -33.80146 -42.77608 1.000 54.67000  ? 418 VAL   C N   1 
ATOM   5208 C CA  . VAL   C 1 204 ? 20.54751  -35.02455 -42.34552 1.000 58.29000  ? 418 VAL   C CA  1 
ATOM   5209 C C   . VAL   C 1 204 ? 19.19945  -34.70067 -41.75058 1.000 64.91000  ? 418 VAL   C C   1 
ATOM   5210 O O   . VAL   C 1 204 ? 19.06342  -33.69686 -41.06831 1.000 74.59000  ? 418 VAL   C O   1 
ATOM   5211 C CB  . VAL   C 1 204 ? 21.39735  -35.77489 -41.31463 1.000 59.12000  ? 418 VAL   C CB  1 
ATOM   5212 C CG1 . VAL   C 1 204 ? 20.74124  -37.08598 -40.92610 1.000 60.85000  ? 418 VAL   C CG1 1 
ATOM   5213 C CG2 . VAL   C 1 204 ? 22.77341  -36.02479 -41.88754 1.000 66.94000  ? 418 VAL   C CG2 1 
ATOM   5214 N N   . SER   C 1 205 ? 18.18544  -35.51355 -41.98994 1.000 61.11000  ? 419 SER   C N   1 
ATOM   5215 C CA  . SER   C 1 205 ? 16.92838  -35.25269 -41.31502 1.000 70.30000  ? 419 SER   C CA  1 
ATOM   5216 C C   . SER   C 1 205 ? 16.96318  -35.58412 -39.84811 1.000 79.21000  ? 419 SER   C C   1 
ATOM   5217 O O   . SER   C 1 205 ? 17.48409  -36.61925 -39.46935 1.000 75.36000  ? 419 SER   C O   1 
ATOM   5218 C CB  . SER   C 1 205 ? 15.81441  -36.05346 -41.92339 1.000 63.01000  ? 419 SER   C CB  1 
ATOM   5219 O OG  . SER   C 1 205 ? 14.61034  -35.81661 -41.22246 1.000 70.78000  ? 419 SER   C OG  1 
ATOM   5220 N N   . THR   C 1 206 ? 16.39512  -34.72934 -39.01893 1.000 82.95000  ? 420 THR   C N   1 
ATOM   5221 C CA  . THR   C 1 206 ? 16.29494  -35.02975 -37.60303 1.000 86.32000  ? 420 THR   C CA  1 
ATOM   5222 C C   . THR   C 1 206 ? 15.41185  -36.22878 -37.35449 1.000 90.97000  ? 420 THR   C C   1 
ATOM   5223 O O   . THR   C 1 206 ? 15.71872  -37.06904 -36.52270 1.000 94.80000  ? 420 THR   C O   1 
ATOM   5224 C CB  . THR   C 1 206 ? 15.71991  -33.82094 -36.85974 1.000 87.19000  ? 420 THR   C CB  1 
ATOM   5225 O OG1 . THR   C 1 206 ? 14.47099  -33.45071 -37.44979 1.000 79.79000  ? 420 THR   C OG1 1 
ATOM   5226 C CG2 . THR   C 1 206 ? 16.67297  -32.65495 -36.95729 1.000 87.12000  ? 420 THR   C CG2 1 
ATOM   5227 N N   . SER   C 1 207 ? 14.30093  -36.32252 -38.06165 1.000 88.69000  ? 421 SER   C N   1 
ATOM   5228 C CA  . SER   C 1 207 ? 13.35085  -37.39855 -37.79808 1.000 95.32000  ? 421 SER   C CA  1 
ATOM   5229 C C   . SER   C 1 207 ? 13.73686  -38.72540 -38.38442 1.000 94.47000  ? 421 SER   C C   1 
ATOM   5230 O O   . SER   C 1 207 ? 14.30199  -38.78611 -39.46237 1.000 94.67000  ? 421 SER   C O   1 
ATOM   5231 C CB  . SER   C 1 207 ? 11.99194  -37.02232 -38.37013 1.000 97.09000  ? 421 SER   C CB  1 
ATOM   5232 O OG  . SER   C 1 207 ? 12.03311  -37.00491 -39.78612 1.000 91.96000  ? 421 SER   C OG  1 
ATOM   5233 N N   . GLU   C 1 208 ? 13.41473  -39.79859 -37.69377 1.000 97.95000  ? 422 GLU   C N   1 
ATOM   5234 C CA  . GLU   C 1 208 ? 13.69074  -41.09943 -38.26412 1.000 102.91000 ? 422 GLU   C CA  1 
ATOM   5235 C C   . GLU   C 1 208 ? 12.79487  -41.32504 -39.45630 1.000 105.80000 ? 422 GLU   C C   1 
ATOM   5236 O O   . GLU   C 1 208 ? 11.61088  -40.99600 -39.41934 1.000 104.33000 ? 422 GLU   C O   1 
ATOM   5237 C CB  . GLU   C 1 208 ? 13.50757  -42.21272 -37.24447 1.000 102.53000 ? 422 GLU   C CB  1 
ATOM   5238 C CG  . GLU   C 1 208 ? 14.82048  -42.78193 -36.73848 1.000 113.08000 ? 422 GLU   C CG  1 
ATOM   5239 C CD  . GLU   C 1 208 ? 14.65233  -44.09514 -36.00188 1.000 117.77000 ? 422 GLU   C CD  1 
ATOM   5240 O OE1 . GLU   C 1 208 ? 13.49929  -44.53514 -35.80915 1.000 120.87000 ? 422 GLU   C OE1 1 
ATOM   5241 O OE2 . GLU   C 1 208 ? 15.67926  -44.69130 -35.61593 1.000 109.59000 ? 422 GLU   C OE2 1 
ATOM   5242 N N   . HIS   C 1 209 ? 13.36398  -41.85476 -40.52438 1.000 101.54000 ? 423 HIS   C N   1 
ATOM   5243 C CA  . HIS   C 1 209 ? 12.59511  -42.14137 -41.73756 1.000 103.08000 ? 423 HIS   C CA  1 
ATOM   5244 C C   . HIS   C 1 209 ? 11.89723  -40.91217 -42.29828 1.000 101.90000 ? 423 HIS   C C   1 
ATOM   5245 O O   . HIS   C 1 209 ? 10.77829  -41.00397 -42.79144 1.000 104.80000 ? 423 HIS   C O   1 
ATOM   5246 C CB  . HIS   C 1 209 ? 11.60103  -43.27338 -41.52001 1.000 106.62000 ? 423 HIS   C CB  1 
ATOM   5247 C CG  . HIS   C 1 209 ? 11.09916  -43.87599 -42.79425 1.000 111.06000 ? 423 HIS   C CG  1 
ATOM   5248 N ND1 . HIS   C 1 209 ? 11.94825  -44.34374 -43.77528 1.000 102.69000 ? 423 HIS   C ND1 1 
ATOM   5249 C CD2 . HIS   C 1 209 ? 9.84420   -44.08280 -43.25246 1.000 104.48000 ? 423 HIS   C CD2 1 
ATOM   5250 C CE1 . HIS   C 1 209 ? 11.23335  -44.81641 -44.78151 1.000 105.12000 ? 423 HIS   C CE1 1 
ATOM   5251 N NE2 . HIS   C 1 209 ? 9.95432   -44.67244 -44.48862 1.000 104.57000 ? 423 HIS   C NE2 1 
ATOM   5252 N N   . GLY   C 1 210 ? 12.54028  -39.75922 -42.22587 1.000 95.37000  ? 424 GLY   C N   1 
ATOM   5253 C CA  . GLY   C 1 210 ? 11.96640  -38.58601 -42.83759 1.000 87.52000  ? 424 GLY   C CA  1 
ATOM   5254 C C   . GLY   C 1 210 ? 12.89355  -37.96876 -43.83630 1.000 75.30000  ? 424 GLY   C C   1 
ATOM   5255 O O   . GLY   C 1 210 ? 14.03353  -37.69491 -43.52508 1.000 79.46000  ? 424 GLY   C O   1 
ATOM   5256 N N   . ALA   C 1 211 ? 12.41671  -37.72639 -45.03429 1.000 60.02000  ? 425 ALA   C N   1 
ATOM   5257 C CA  . ALA   C 1 211 ? 13.22486  -37.02315 -45.99198 1.000 61.18000  ? 425 ALA   C CA  1 
ATOM   5258 C C   . ALA   C 1 211 ? 12.43095  -35.80701 -46.33872 1.000 54.67000  ? 425 ALA   C C   1 
ATOM   5259 O O   . ALA   C 1 211 ? 11.25298  -35.90187 -46.62689 1.000 66.42000  ? 425 ALA   C O   1 
ATOM   5260 C CB  . ALA   C 1 211 ? 13.49696  -37.87181 -47.20220 1.000 47.36000  ? 425 ALA   C CB  1 
ATOM   5261 N N   . GLN   C 1 212 ? 13.06500  -34.65705 -46.30131 1.000 48.54000  ? 426 GLN   C N   1 
ATOM   5262 C CA  . GLN   C 1 212 ? 12.36209  -33.43895 -46.54604 1.000 51.68000  ? 426 GLN   C CA  1 
ATOM   5263 C C   . GLN   C 1 212 ? 13.13524  -32.60470 -47.48970 1.000 45.67000  ? 426 GLN   C C   1 
ATOM   5264 O O   . GLN   C 1 212 ? 14.34024  -32.72373 -47.57959 1.000 51.81000  ? 426 GLN   C O   1 
ATOM   5265 C CB  . GLN   C 1 212 ? 12.18897  -32.68432 -45.24684 1.000 54.67000  ? 426 GLN   C CB  1 
ATOM   5266 C CG  . GLN   C 1 212 ? 11.04484  -33.15852 -44.37611 1.000 60.48000  ? 426 GLN   C CG  1 
ATOM   5267 C CD  . GLN   C 1 212 ? 11.00971  -32.45191 -43.03891 1.000 64.75000  ? 426 GLN   C CD  1 
ATOM   5268 O OE1 . GLN   C 1 212 ? 9.97468   -31.95299 -42.61689 1.000 54.35000  ? 426 GLN   C OE1 1 
ATOM   5269 N NE2 . GLN   C 1 212 ? 12.15063  -32.40316 -42.36576 1.000 62.24000  ? 426 GLN   C NE2 1 
ATOM   5270 N N   . HIS   C 1 213 ? 12.44037  -31.76646 -48.22354 1.000 50.95000  ? 427 HIS   C N   1 
ATOM   5271 C CA  . HIS   C 1 213 ? 13.14751  -30.85924 -49.08219 1.000 51.25000  ? 427 HIS   C CA  1 
ATOM   5272 C C   . HIS   C 1 213 ? 12.49859  -29.51416 -49.24087 1.000 55.32000  ? 427 HIS   C C   1 
ATOM   5273 O O   . HIS   C 1 213 ? 11.28759  -29.39013 -49.15898 1.000 51.31000  ? 427 HIS   C O   1 
ATOM   5274 C CB  . HIS   C 1 213 ? 13.39165  -31.49485 -50.45634 1.000 46.82000  ? 427 HIS   C CB  1 
ATOM   5275 C CG  . HIS   C 1 213 ? 12.18375  -31.59254 -51.32252 1.000 56.81000  ? 427 HIS   C CG  1 
ATOM   5276 N ND1 . HIS   C 1 213 ? 11.84890  -30.62025 -52.23727 1.000 56.16000  ? 427 HIS   C ND1 1 
ATOM   5277 C CD2 . HIS   C 1 213 ? 11.25572  -32.56646 -51.45091 1.000 51.74000  ? 427 HIS   C CD2 1 
ATOM   5278 C CE1 . HIS   C 1 213 ? 10.75296  -30.97902 -52.87551 1.000 59.83000  ? 427 HIS   C CE1 1 
ATOM   5279 N NE2 . HIS   C 1 213 ? 10.37485  -32.15913 -52.41890 1.000 63.40000  ? 427 HIS   C NE2 1 
ATOM   5280 N N   . HIS   C 1 214 ? 13.31666  -28.49915 -49.41648 1.000 49.09000  ? 428 HIS   C N   1 
ATOM   5281 C CA  . HIS   C 1 214 ? 12.84375  -27.15205 -49.68814 1.000 54.92000  ? 428 HIS   C CA  1 
ATOM   5282 C C   . HIS   C 1 214 ? 13.30494  -26.78566 -51.09697 1.000 48.13000  ? 428 HIS   C C   1 
ATOM   5283 O O   . HIS   C 1 214 ? 14.39997  -27.17458 -51.51196 1.000 50.43000  ? 428 HIS   C O   1 
ATOM   5284 C CB  . HIS   C 1 214 ? 13.38267  -26.15238 -48.64378 1.000 54.39000  ? 428 HIS   C CB  1 
ATOM   5285 C CG  . HIS   C 1 214 ? 12.93649  -26.41577 -47.22791 1.000 46.67000  ? 428 HIS   C CG  1 
ATOM   5286 N ND1 . HIS   C 1 214 ? 13.36940  -25.64810 -46.16963 1.000 44.44000  ? 428 HIS   C ND1 1 
ATOM   5287 C CD2 . HIS   C 1 214 ? 12.10939  -27.35289 -46.69728 1.000 55.36000  ? 428 HIS   C CD2 1 
ATOM   5288 C CE1 . HIS   C 1 214 ? 12.82725  -26.09341 -45.04583 1.000 56.43000  ? 428 HIS   C CE1 1 
ATOM   5289 N NE2 . HIS   C 1 214 ? 12.06023  -27.13329 -45.33223 1.000 62.62000  ? 428 HIS   C NE2 1 
ATOM   5290 N N   . VAL   C 1 215 ? 12.46106  -26.08240 -51.85287 1.000 48.18000  ? 429 VAL   C N   1 
ATOM   5291 C CA  . VAL   C 1 215 ? 12.77225  -25.70400 -53.23472 1.000 53.43000  ? 429 VAL   C CA  1 
ATOM   5292 C C   . VAL   C 1 215 ? 12.79733  -24.18198 -53.32627 1.000 49.97000  ? 429 VAL   C C   1 
ATOM   5293 O O   . VAL   C 1 215 ? 11.84331  -23.51906 -52.90519 1.000 56.28000  ? 429 VAL   C O   1 
ATOM   5294 C CB  . VAL   C 1 215 ? 11.76334  -26.29366 -54.24502 1.000 47.27000  ? 429 VAL   C CB  1 
ATOM   5295 C CG1 . VAL   C 1 215 ? 11.96253  -25.67527 -55.60381 1.000 51.60000  ? 429 VAL   C CG1 1 
ATOM   5296 C CG2 . VAL   C 1 215 ? 11.91529  -27.79463 -54.36644 1.000 48.51000  ? 429 VAL   C CG2 1 
ATOM   5297 N N   . TYR   C 1 216 ? 13.88142  -23.62487 -53.86398 1.000 43.79000  ? 430 TYR   C N   1 
ATOM   5298 C CA  . TYR   C 1 216 ? 14.00150  -22.17485 -53.97154 1.000 50.54000  ? 430 TYR   C CA  1 
ATOM   5299 C C   . TYR   C 1 216 ? 14.36269  -21.77844 -55.39438 1.000 44.22000  ? 430 TYR   C C   1 
ATOM   5300 O O   . TYR   C 1 216 ? 15.03674  -22.52027 -56.09752 1.000 48.50000  ? 430 TYR   C O   1 
ATOM   5301 C CB  . TYR   C 1 216 ? 15.08141  -21.57417 -53.04423 1.000 50.02000  ? 430 TYR   C CB  1 
ATOM   5302 C CG  . TYR   C 1 216 ? 15.06622  -22.01559 -51.60437 1.000 50.40000  ? 430 TYR   C CG  1 
ATOM   5303 C CD1 . TYR   C 1 216 ? 15.77212  -23.14374 -51.19961 1.000 46.62000  ? 430 TYR   C CD1 1 
ATOM   5304 C CD2 . TYR   C 1 216 ? 14.37114  -21.28884 -50.63624 1.000 51.77000  ? 430 TYR   C CD2 1 
ATOM   5305 C CE1 . TYR   C 1 216 ? 15.77894  -23.55513 -49.87673 1.000 51.83000  ? 430 TYR   C CE1 1 
ATOM   5306 C CE2 . TYR   C 1 216 ? 14.37596  -21.68723 -49.28635 1.000 50.62000  ? 430 TYR   C CE2 1 
ATOM   5307 C CZ  . TYR   C 1 216 ? 15.07686  -22.82937 -48.91860 1.000 53.82000  ? 430 TYR   C CZ  1 
ATOM   5308 O OH  . TYR   C 1 216 ? 15.09768  -23.24076 -47.60472 1.000 55.82000  ? 430 TYR   C OH  1 
ATOM   5309 N N   . LYS   C 1 217 ? 13.93579  -20.58531 -55.79608 1.000 43.72000  ? 431 LYS   C N   1 
ATOM   5310 C CA  . LYS   C 1 217 ? 14.33697  -19.98196 -57.05486 1.000 43.06000  ? 431 LYS   C CA  1 
ATOM   5311 C C   . LYS   C 1 217 ? 15.51298  -19.05309 -56.78044 1.000 50.86000  ? 431 LYS   C C   1 
ATOM   5312 O O   . LYS   C 1 217 ? 15.44591  -18.22436 -55.86821 1.000 50.64000  ? 431 LYS   C O   1 
ATOM   5313 C CB  . LYS   C 1 217 ? 13.16308  -19.23272 -57.69178 1.000 47.96000  ? 431 LYS   C CB  1 
ATOM   5314 C CG  . LYS   C 1 217 ? 13.15013  -17.70578 -57.47833 1.000 56.88000  ? 431 LYS   C CG  1 
ATOM   5315 C CD  . LYS   C 1 217 ? 11.73216  -17.11070 -57.53933 1.000 55.62000  ? 431 LYS   C CD  1 
ATOM   5316 C CE  . LYS   C 1 217 ? 11.03230  -17.52929 -58.82254 1.000 52.66000  ? 431 LYS   C CE  1 
ATOM   5317 N NZ  . LYS   C 1 217 ? 9.95038   -16.57014 -59.15439 1.000 64.50000  ? 431 LYS   C NZ  1 
ATOM   5318 N N   . LEU   C 1 218 ? 16.60906  -19.23693 -57.51737 1.000 49.67000  ? 432 LEU   C N   1 
ATOM   5319 C CA  . LEU   C 1 218 ? 17.82207  -18.46605 -57.27499 1.000 45.29000  ? 432 LEU   C CA  1 
ATOM   5320 C C   . LEU   C 1 218 ? 17.72821  -17.10085 -57.94261 1.000 49.19000  ? 432 LEU   C C   1 
ATOM   5321 O O   . LEU   C 1 218 ? 17.48336  -17.00149 -59.14561 1.000 49.21000  ? 432 LEU   C O   1 
ATOM   5322 C CB  . LEU   C 1 218 ? 19.02309  -19.23696 -57.79708 1.000 46.68000  ? 432 LEU   C CB  1 
ATOM   5323 C CG  . LEU   C 1 218 ? 19.43693  -20.34525 -56.84335 1.000 47.95000  ? 432 LEU   C CG  1 
ATOM   5324 C CD1 . LEU   C 1 218 ? 20.38496  -21.36811 -57.48454 1.000 37.08000  ? 432 LEU   C CD1 1 
ATOM   5325 C CD2 . LEU   C 1 218 ? 20.09681  -19.66864 -55.63607 1.000 48.14000  ? 432 LEU   C CD2 1 
ATOM   5326 N N   . VAL   C 1 219 ? 17.93116  -16.04009 -57.16327 1.000 49.20000  ? 433 VAL   C N   1 
ATOM   5327 C CA  . VAL   C 1 219 ? 17.79929  -14.67994 -57.66289 1.000 48.41000  ? 433 VAL   C CA  1 
ATOM   5328 C C   . VAL   C 1 219 ? 19.10429  -13.93108 -57.39851 1.000 46.64000  ? 433 VAL   C C   1 
ATOM   5329 O O   . VAL   C 1 219 ? 20.00318  -14.41832 -56.71055 1.000 47.67000  ? 433 VAL   C O   1 
ATOM   5330 C CB  . VAL   C 1 219 ? 16.59724  -13.93707 -57.02681 1.000 48.58000  ? 433 VAL   C CB  1 
ATOM   5331 C CG1 . VAL   C 1 219 ? 15.30125  -14.67792 -57.33819 1.000 44.49000  ? 433 VAL   C CG1 1 
ATOM   5332 C CG2 . VAL   C 1 219 ? 16.78007  -13.78252 -55.53175 1.000 44.25000  ? 433 VAL   C CG2 1 
ATOM   5333 N N   . LYS   C 1 220 ? 19.18441  -12.72192 -57.93415 1.000 42.23000  ? 434 LYS   C N   1 
ATOM   5334 C CA  . LYS   C 1 220 ? 20.36943  -11.90201 -57.80477 1.000 54.89000  ? 434 LYS   C CA  1 
ATOM   5335 C C   . LYS   C 1 220 ? 19.93448  -10.45203 -57.67739 1.000 62.15000  ? 434 LYS   C C   1 
ATOM   5336 O O   . LYS   C 1 220 ? 20.13163  -9.63878  -58.57513 1.000 70.77000  ? 434 LYS   C O   1 
ATOM   5337 C CB  . LYS   C 1 220 ? 21.34257  -12.07372 -58.97870 1.000 51.36000  ? 434 LYS   C CB  1 
ATOM   5338 C CG  . LYS   C 1 220 ? 22.71355  -11.53687 -58.65038 1.000 51.27000  ? 434 LYS   C CG  1 
ATOM   5339 C CD  . LYS   C 1 220 ? 23.58071  -11.27256 -59.86519 1.000 56.28000  ? 434 LYS   C CD  1 
ATOM   5340 C CE  . LYS   C 1 220 ? 24.28372  -12.51144 -60.39447 1.000 52.91000  ? 434 LYS   C CE  1 
ATOM   5341 N NZ  . LYS   C 1 220 ? 25.00188  -12.18209 -61.67129 1.000 55.76000  ? 434 LYS   C NZ  1 
ATOM   5342 N N   . ASP   C 1 221 ? 19.35036  -10.12434 -56.53537 1.000 65.07000  ? 435 ASP   C N   1 
ATOM   5343 C CA  . ASP   C 1 221 ? 18.99939  -8.73841  -56.25300 1.000 73.01000  ? 435 ASP   C CA  1 
ATOM   5344 C C   . ASP   C 1 221 ? 20.28939  -7.97656  -55.93662 1.000 68.95000  ? 435 ASP   C C   1 
ATOM   5345 O O   . ASP   C 1 221 ? 20.29734  -7.02379  -55.16134 1.000 70.43000  ? 435 ASP   C O   1 
ATOM   5346 C CB  . ASP   C 1 221 ? 18.00026  -8.64270  -55.09509 1.000 75.62000  ? 435 ASP   C CB  1 
ATOM   5347 C CG  . ASP   C 1 221 ? 16.73025  -9.45757  -55.34249 1.000 87.11000  ? 435 ASP   C CG  1 
ATOM   5348 O OD1 . ASP   C 1 221 ? 16.25939  -9.52121  -56.50356 1.000 83.76000  ? 435 ASP   C OD1 1 
ATOM   5349 O OD2 . ASP   C 1 221 ? 16.21310  -10.05183 -54.36572 1.000 98.82000  ? 435 ASP   C OD2 1 
HETATM 5350 N N1  . A1L1N D 2 .   ? 11.47200  -12.37800 -3.31800  0.870 54.14000  ? 501 A1L1N A N1  1 
HETATM 5351 C C4  . A1L1N D 2 .   ? 9.18500   -13.14600 -1.70200  0.870 39.33000  ? 501 A1L1N A C4  1 
HETATM 5352 C C5  . A1L1N D 2 .   ? 9.14100   -11.86800 -2.53500  0.870 48.02000  ? 501 A1L1N A C5  1 
HETATM 5353 C C6  . A1L1N D 2 .   ? 10.26000  -15.27300 -1.30800  0.870 40.28000  ? 501 A1L1N A C6  1 
HETATM 5354 C C7  . A1L1N D 2 .   ? 9.37700   -15.51600 -0.25900  0.870 36.47000  ? 501 A1L1N A C7  1 
HETATM 5355 C C8  . A1L1N D 2 .   ? 8.40300   -14.58300 0.09300   0.870 38.27000  ? 501 A1L1N A C8  1 
HETATM 5356 C C10 . A1L1N D 2 .   ? 12.73500  -11.98900 -3.92400  0.870 55.41000  ? 501 A1L1N A C10 1 
HETATM 5357 C C13 . A1L1N D 2 .   ? 9.53500   -16.82900 0.52900   0.870 36.44000  ? 501 A1L1N A C13 1 
HETATM 5358 C C15 . A1L1N D 2 .   ? 9.55400   -17.96400 2.63600   0.870 44.82000  ? 501 A1L1N A C15 1 
HETATM 5359 C C17 . A1L1N D 2 .   ? 10.02100  -19.17200 0.60200   0.870 42.48000  ? 501 A1L1N A C17 1 
HETATM 5360 C C1  . A1L1N D 2 .   ? 10.54600  -11.37200 -2.81500  0.870 48.58000  ? 501 A1L1N A C1  1 
HETATM 5361 C C11 . A1L1N D 2 .   ? 13.06700  -10.51400 -4.02700  0.870 61.23000  ? 501 A1L1N A C11 1 
HETATM 5362 C C12 . A1L1N D 2 .   ? 13.55500  -10.23900 -5.44700  0.870 56.64000  ? 501 A1L1N A C12 1 
HETATM 5363 C C14 . A1L1N D 2 .   ? 9.39300   -16.79600 1.90300   0.870 38.52000  ? 501 A1L1N A C14 1 
HETATM 5364 C C16 . A1L1N D 2 .   ? 9.86600   -19.14500 1.97700   0.870 43.97000  ? 501 A1L1N A C16 1 
HETATM 5365 C C18 . A1L1N D 2 .   ? 9.86000   -18.00500 -0.13300  0.870 39.57000  ? 501 A1L1N A C18 1 
HETATM 5366 C C19 . A1L1N D 2 .   ? 10.04200  -20.42800 2.78400   0.870 50.27000  ? 501 A1L1N A C19 1 
HETATM 5367 C C2  . A1L1N D 2 .   ? 11.10400  -13.78900 -3.20000  0.870 47.41000  ? 501 A1L1N A C2  1 
HETATM 5368 C C3  . A1L1N D 2 .   ? 10.13100  -14.05800 -2.02200  0.870 38.61000  ? 501 A1L1N A C3  1 
HETATM 5369 C C9  . A1L1N D 2 .   ? 8.28900   -13.38700 -0.62700  0.870 43.50000  ? 501 A1L1N A C9  1 
HETATM 5370 F F1  . A1L1N D 2 .   ? 11.02300  -21.17800 2.22300   0.870 58.45000  ? 501 A1L1N A F1  1 
HETATM 5371 F F2  . A1L1N D 2 .   ? 10.38700  -20.11000 4.05800   0.870 48.10000  ? 501 A1L1N A F2  1 
HETATM 5372 F F3  . A1L1N D 2 .   ? 8.87600   -21.12600 2.77800   0.870 52.04000  ? 501 A1L1N A F3  1 
HETATM 5373 F F4  . A1L1N D 2 .   ? 11.92800  -9.80900  -3.81200  0.870 74.36000  ? 501 A1L1N A F4  1 
HETATM 5374 O O1  . A1L1N D 2 .   ? 13.48100  -12.80900 -4.33500  0.870 52.74000  ? 501 A1L1N A O1  1 
HETATM 5375 N N1  . A1L1N E 2 .   ? -5.53178  -16.68241 -31.71834 0.920 49.79000  ? 501 A1L1N B N1  1 
HETATM 5376 C C4  . A1L1N E 2 .   ? -3.06906  -17.77020 -32.84715 0.920 47.87000  ? 501 A1L1N B C4  1 
HETATM 5377 C C5  . A1L1N E 2 .   ? -3.16601  -16.31023 -32.41004 0.920 52.70000  ? 501 A1L1N B C5  1 
HETATM 5378 C C6  . A1L1N E 2 .   ? -4.06390  -19.96827 -32.74398 0.920 42.84000  ? 501 A1L1N B C6  1 
HETATM 5379 C C7  . A1L1N E 2 .   ? -3.05212  -20.45716 -33.56231 0.920 42.79000  ? 501 A1L1N B C7  1 
HETATM 5380 C C8  . A1L1N E 2 .   ? -2.04632  -19.62207 -34.05157 0.920 42.15000  ? 501 A1L1N B C8  1 
HETATM 5381 C C10 . A1L1N E 2 .   ? -6.76865  -16.15151 -31.16793 0.920 54.40000  ? 501 A1L1N B C10 1 
HETATM 5382 C C13 . A1L1N E 2 .   ? -3.14015  -21.94614 -33.93137 0.920 42.96000  ? 501 A1L1N B C13 1 
HETATM 5383 C C15 . A1L1N E 2 .   ? -3.19957  -23.62705 -35.62945 0.920 43.17000  ? 501 A1L1N B C15 1 
HETATM 5384 C C17 . A1L1N E 2 .   ? -3.43683  -24.23720 -33.31341 0.920 48.57000  ? 501 A1L1N B C17 1 
HETATM 5385 C C1  . A1L1N E 2 .   ? -4.61707  -15.86931 -32.50357 0.920 46.72000  ? 501 A1L1N B C1  1 
HETATM 5386 C C11 . A1L1N E 2 .   ? -7.13581  -14.70152 -31.42074 0.920 57.42000  ? 501 A1L1N B C11 1 
HETATM 5387 C C12 . A1L1N E 2 .   ? -7.62545  -14.08062 -30.11255 0.920 60.54000  ? 501 A1L1N B C12 1 
HETATM 5388 C C14 . A1L1N E 2 .   ? -3.09253  -22.29206 -35.26640 0.920 39.17000  ? 501 A1L1N B C14 1 
HETATM 5389 C C16 . A1L1N E 2 .   ? -3.37021  -24.58811 -34.64645 0.920 40.83000  ? 501 A1L1N B C16 1 
HETATM 5390 C C18 . A1L1N E 2 .   ? -3.32879  -22.90221 -32.94637 0.920 49.22000  ? 501 A1L1N B C18 1 
HETATM 5391 C C19 . A1L1N E 2 .   ? -3.49125  -26.05210 -35.04950 0.920 44.49000  ? 501 A1L1N B C19 1 
HETATM 5392 C C2  . A1L1N E 2 .   ? -5.17063  -18.07440 -31.47353 0.920 52.08000  ? 501 A1L1N B C2  1 
HETATM 5393 C C3  . A1L1N E 2 .   ? -4.04288  -18.59828 -32.40090 0.920 47.04000  ? 501 A1L1N B C3  1 
HETATM 5394 C C9  . A1L1N E 2 .   ? -2.03929  -18.26609 -33.69449 0.920 41.04000  ? 501 A1L1N B C9  1 
HETATM 5395 F F1  . A1L1N E 2 .   ? -4.55502  -26.60420 -34.41721 0.920 51.99000  ? 501 A1L1N B F1  1 
HETATM 5396 F F2  . A1L1N E 2 .   ? -3.66465  -26.11203 -36.39045 0.920 53.31000  ? 501 A1L1N B F2  1 
HETATM 5397 F F3  . A1L1N E 2 .   ? -2.36410  -26.72205 -34.70688 0.920 50.47000  ? 501 A1L1N B F3  1 
HETATM 5398 F F4  . A1L1N E 2 .   ? -6.02397  -14.05143 -31.83304 0.920 70.72000  ? 501 A1L1N B F4  1 
HETATM 5399 O O1  . A1L1N E 2 .   ? -7.47241  -16.85359 -30.52576 0.920 51.48000  ? 501 A1L1N B O1  1 
HETATM 5400 N N1  . A1L1N F 2 .   ? 25.24211  -39.66535 -57.42531 0.910 59.81000  ? 501 A1L1N C N1  1 
HETATM 5401 C C4  . A1L1N F 2 .   ? 23.14302  -38.10464 -56.09611 0.910 41.04000  ? 501 A1L1N C C4  1 
HETATM 5402 C C5  . A1L1N F 2 .   ? 23.30020  -38.09921 -57.61509 0.910 57.88000  ? 501 A1L1N C C5  1 
HETATM 5403 C C6  . A1L1N F 2 .   ? 23.74272  -39.13629 -54.00034 0.910 49.50000  ? 501 A1L1N C C6  1 
HETATM 5404 C C7  . A1L1N F 2 .   ? 22.94968  -38.21445 -53.32216 0.910 45.70000  ? 501 A1L1N C C7  1 
HETATM 5405 C C8  . A1L1N F 2 .   ? 22.24981  -37.21921 -54.00596 0.910 47.82000  ? 501 A1L1N C C8  1 
HETATM 5406 C C10 . A1L1N F 2 .   ? 26.25616  -40.44419 -58.12142 0.910 60.41000  ? 501 A1L1N C C10 1 
HETATM 5407 C C13 . A1L1N F 2 .   ? 22.92449  -38.34690 -51.78921 0.910 51.37000  ? 501 A1L1N C C13 1 
HETATM 5408 C C15 . A1L1N F 2 .   ? 23.13627  -37.37654 -49.60890 0.910 44.83000  ? 501 A1L1N C C15 1 
HETATM 5409 C C17 . A1L1N F 2 .   ? 22.73620  -39.74245 -49.85564 0.910 51.44000  ? 501 A1L1N C C17 1 
HETATM 5410 C C1  . A1L1N F 2 .   ? 24.73123  -38.42816 -57.99801 0.910 57.95000  ? 501 A1L1N C C1  1 
HETATM 5411 C C11 . A1L1N F 2 .   ? 26.77134  -39.94283 -59.45821 0.910 77.95000  ? 501 A1L1N C C11 1 
HETATM 5412 C C12 . A1L1N F 2 .   ? 26.79940  -41.11654 -60.43755 0.910 69.26000  ? 501 A1L1N C C12 1 
HETATM 5413 C C14 . A1L1N F 2 .   ? 23.13845  -37.23414 -50.99285 0.910 52.38000  ? 501 A1L1N C C14 1 
HETATM 5414 C C16 . A1L1N F 2 .   ? 22.93615  -38.63470 -49.05929 0.910 47.61000  ? 501 A1L1N C C16 1 
HETATM 5415 C C18 . A1L1N F 2 .   ? 22.73837  -39.60305 -51.23460 0.910 54.57000  ? 501 A1L1N C C18 1 
HETATM 5416 C C19 . A1L1N F 2 .   ? 22.93596  -38.81814 -47.54734 0.910 52.31000  ? 501 A1L1N C C19 1 
HETATM 5417 C C2  . A1L1N F 2 .   ? 24.70693  -40.10670 -56.13751 0.910 55.30000  ? 501 A1L1N C C2  1 
HETATM 5418 C C3  . A1L1N F 2 .   ? 23.82189  -39.05388 -55.41030 0.910 51.18000  ? 501 A1L1N C C3  1 
HETATM 5419 C C9  . A1L1N F 2 .   ? 22.33498  -37.15581 -55.40593 0.910 48.37000  ? 501 A1L1N C C9  1 
HETATM 5420 F F1  . A1L1N F 2 .   ? 23.93588  -39.67128 -47.21747 0.910 59.43000  ? 501 A1L1N C F1  1 
HETATM 5421 F F2  . A1L1N F 2 .   ? 23.13795  -37.61232 -46.95996 0.910 49.20000  ? 501 A1L1N C F2  1 
HETATM 5422 F F3  . A1L1N F 2 .   ? 21.74689  -39.34820 -47.15064 0.910 60.05000  ? 501 A1L1N C F3  1 
HETATM 5423 F F4  . A1L1N F 2 .   ? 25.90844  -38.99465 -59.91304 0.910 75.00000  ? 501 A1L1N C F4  1 
HETATM 5424 O O1  . A1L1N F 2 .   ? 26.66705  -41.45135 -57.65767 0.910 52.41000  ? 501 A1L1N C O1  1 
HETATM 5425 O O   . HOH   G 3 .   ? 9.62600   -16.48800 -16.46100 1.000 55.53000  ? 601 HOH   A O   1 
HETATM 5426 O O   . HOH   G 3 .   ? -0.95000  10.31900  -6.25600  1.000 57.32000  ? 602 HOH   A O   1 
HETATM 5427 O O   . HOH   G 3 .   ? 6.93400   -8.47600  -5.93900  1.000 49.84000  ? 603 HOH   A O   1 
HETATM 5428 O O   . HOH   G 3 .   ? 10.18200  -29.25500 14.25000  1.000 51.85000  ? 604 HOH   A O   1 
HETATM 5429 O O   . HOH   G 3 .   ? 16.89600  -5.57100  15.67700  1.000 52.10000  ? 605 HOH   A O   1 
HETATM 5430 O O   . HOH   G 3 .   ? 15.23500  -8.02300  14.95000  1.000 54.24000  ? 606 HOH   A O   1 
HETATM 5431 O O   . HOH   G 3 .   ? 18.083    -10.089   17.935    1.000 59.39000  ? 607 HOH   A O   1 
HETATM 5432 O O   . HOH   H 3 .   ? -8.36900  -4.43500  -45.34000 1.000 60.49000  ? 601 HOH   B O   1 
HETATM 5433 O O   . HOH   H 3 .   ? 1.44900   -1.32900  -54.40000 1.000 54.23000  ? 602 HOH   B O   1 
HETATM 5434 O O   . HOH   H 3 .   ? -6.37100  -27.82800 -50.34100 1.000 59.11000  ? 603 HOH   B O   1 
HETATM 5435 O O   . HOH   H 3 .   ? 0.45300   -21.41600 -19.48300 1.000 57.35000  ? 604 HOH   B O   1 
HETATM 5436 O O   . HOH   H 3 .   ? 0.43900   -32.72300 -35.43500 1.000 60.14000  ? 605 HOH   B O   1 
HETATM 5437 O O   . HOH   H 3 .   ? -18.66600 -13.07700 -48.76000 1.000 65.80000  ? 606 HOH   B O   1 
HETATM 5438 O O   . HOH   H 3 .   ? -2.95300  0.34300   -52.28000 1.000 63.67000  ? 607 HOH   B O   1 
HETATM 5439 O O   . HOH   H 3 .   ? -7.75400  -19.85500 -49.47900 1.000 55.24000  ? 608 HOH   B O   1 
HETATM 5440 O O   . HOH   H 3 .   ? -3.74800  -7.64200  -38.05300 1.000 43.31000  ? 609 HOH   B O   1 
HETATM 5441 O O   . HOH   H 3 .   ? 17.07900  -23.34200 -39.09800 1.000 41.09000  ? 610 HOH   B O   1 
HETATM 5442 O O   . HOH   H 3 .   ? -14.14400 -9.56000  -37.67100 1.000 53.88000  ? 611 HOH   B O   1 
HETATM 5443 O O   . HOH   H 3 .   ? 4.44900   -29.43300 -26.83400 1.000 50.47000  ? 612 HOH   B O   1 
HETATM 5444 O O   . HOH   H 3 .   ? -11.235   -22.364   -20.150   1.000 45.56000  ? 613 HOH   B O   1 
HETATM 5445 O O   . HOH   H 3 .   ? -7.74300  -17.40700 -50.94500 1.000 59.22000  ? 614 HOH   B O   1 
HETATM 5446 O O   . HOH   H 3 .   ? -12.828   -24.287   -19.936   1.000 51.30000  ? 615 HOH   B O   1 
HETATM 5447 O O   . HOH   I 3 .   ? 25.80700  -28.46800 -39.36100 1.000 56.69000  ? 601 HOH   C O   1 
HETATM 5448 O O   . HOH   I 3 .   ? 21.16400  -29.20100 -78.79500 1.000 70.52000  ? 602 HOH   C O   1 
HETATM 5449 O O   . HOH   I 3 .   ? 32.02300  -24.02700 -76.26400 1.000 53.96000  ? 603 HOH   C O   1 
HETATM 5450 O O   . HOH   I 3 .   ? 17.63500  -42.05800 -73.90000 1.000 58.63000  ? 604 HOH   C O   1 
HETATM 5451 O O   . HOH   I 3 .   ? 3.38900   -21.58700 -56.70000 1.000 55.80000  ? 605 HOH   C O   1 
HETATM 5452 O O   . HOH   I 3 .   ? 24.68400  -36.44200 -65.11300 1.000 46.33000  ? 606 HOH   C O   1 
HETATM 5453 O O   . HOH   I 3 .   ? 27.09100  -32.06900 -70.00100 1.000 48.93000  ? 607 HOH   C O   1 
HETATM 5454 O O   . HOH   I 3 .   ? 14.46700  -32.33200 -39.95500 1.000 61.35000  ? 608 HOH   C O   1 
HETATM 5455 O O   . HOH   I 3 .   ? 25.82500  -29.70500 -69.21800 1.000 49.51000  ? 609 HOH   C O   1 
HETATM 5456 O O   . HOH   I 3 .   ? 9.42000   -23.36200 -61.51200 1.000 45.36000  ? 610 HOH   C O   1 
HETATM 5457 O O   . HOH   I 3 .   ? 21.96800  -37.80700 -62.52600 1.000 57.11000  ? 611 HOH   C O   1 
HETATM 5458 O O   . HOH   I 3 .   ? 10.34100  -45.14100 -56.06600 1.000 59.01000  ? 612 HOH   C O   1 
# 
