data_8ZAA
# 
_entry.id   8ZAA 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8ZAA         pdb_00008zaa 10.2210/pdb8zaa/pdb 
WWPDB D_1300047285 ?            ?                   
EMDB  EMD-39876    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-04-30 ? 
2 'EM metadata'     1 0 2025-04-30 ? 
3 'Half map'        1 0 2025-04-30 1 
4 'Half map'        1 0 2025-04-30 2 
5 Image             1 0 2025-04-30 ? 
6 'Primary map'     1 0 2025-04-30 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1 1 'Structure model' repository 'Initial release' ? ? 
2 2 'EM metadata'     repository 'Initial release' ? ? 
3 3 'Half map'        repository 'Initial release' ? ? 
4 4 'Half map'        repository 'Initial release' ? ? 
5 5 Image             repository 'Initial release' ? ? 
6 6 'Primary map'     repository 'Initial release' ? ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8ZAA 
_pdbx_database_status.recvd_initial_deposition_date   2024-04-24 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBC 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Cryo-EM structure of intracellular HBMBPP-BTN2A1-BTN3A1 complex' 
_pdbx_database_related.db_id          EMD-39876 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 3 
_pdbx_contact_author.email              huangzhiwei@hit.edu.cn 
_pdbx_contact_author.name_first         Zhiwei 
_pdbx_contact_author.name_last          Huang 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-1264-5984 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Zheng, J.' 1 ? 
'Gao, W.'   2 ? 
'Zhu, Y.'   3 ? 
'Huang, Z.' 4 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'Cryo-EM structure of intracellular HBMBPP-BTN2A1-BTN3A1 complex' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Zheng, J.' 1 ? 
primary 'Gao, W.'   2 ? 
primary 'Zhu, Y.'   3 ? 
primary 'Huang, Z.' 4 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Butyrophilin subfamily 3 member A1'   26462.047 2 ? ? ? ? 
2 polymer     man 'Butyrophilin subfamily 2 member A1'   30227.328 2 ? ? ? ? 
3 non-polymer syn '4-HYDROXY-3-METHYL BUTYL DIPHOSPHATE' 264.107   1 ? ? ? ? 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;EQELREMAWSTMKQEQSTRVKLLEELRWRSIQYASRGERHSAYNEWKKALFKPADVILDPKTANPILLVSEDQRSVQRAK
EPQDLPDNPERFNWHYCVLGCESFISGRHYWEVEVGDRKEWHIGVCSKNVQRKGWVKMTPENGFWTMGLTDGNKYRTLTE
PRTNLKLPKTPKKVGVFLDYETGDISFYNAVDGSHIHTFLDVSFSEALYPVFRILTLEPTALTICPA
;
;EQELREMAWSTMKQEQSTRVKLLEELRWRSIQYASRGERHSAYNEWKKALFKPADVILDPKTANPILLVSEDQRSVQRAK
EPQDLPDNPERFNWHYCVLGCESFISGRHYWEVEVGDRKEWHIGVCSKNVQRKGWVKMTPENGFWTMGLTDGNKYRTLTE
PRTNLKLPKTPKKVGVFLDYETGDISFYNAVDGSHIHTFLDVSFSEALYPVFRILTLEPTALTICPA
;
C,D ? 
2 'polypeptide(L)' no no 
;WINKLQKEKKILSGEKEFERETREIALKELEKERVQKEEELQVKEKLQEELRWRRTFLHAVDVVLDPDTAHPDLFLSEDR
RSVRRCPFRHLGESVPDNPERFDSQPCVLGRESFASGKHYWEVEVENVIEWTVGVCRDSVERKGEVLLIPQNGFWTLEMH
KGQYRAVSSPDRILPLKESLCRVGVFLDYEAGDVSFYNMRDRSHIYTCPRSAFSVPVRPFFRLGCEDSPIFICPALTGAN
GVTVPEEGLTLHRVGTHQSL
;
;WINKLQKEKKILSGEKEFERETREIALKELEKERVQKEEELQVKEKLQEELRWRRTFLHAVDVVLDPDTAHPDLFLSEDR
RSVRRCPFRHLGESVPDNPERFDSQPCVLGRESFASGKHYWEVEVENVIEWTVGVCRDSVERKGEVLLIPQNGFWTLEMH
KGQYRAVSSPDRILPLKESLCRVGVFLDYEAGDVSFYNMRDRSHIYTCPRSAFSVPVRPFFRLGCEDSPIFICPALTGAN
GVTVPEEGLTLHRVGTHQSL
;
G,E ? 
# 
_pdbx_entity_nonpoly.entity_id   3 
_pdbx_entity_nonpoly.name        '4-HYDROXY-3-METHYL BUTYL DIPHOSPHATE' 
_pdbx_entity_nonpoly.comp_id     EIP 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   GLU n 
1 2   GLN n 
1 3   GLU n 
1 4   LEU n 
1 5   ARG n 
1 6   GLU n 
1 7   MET n 
1 8   ALA n 
1 9   TRP n 
1 10  SER n 
1 11  THR n 
1 12  MET n 
1 13  LYS n 
1 14  GLN n 
1 15  GLU n 
1 16  GLN n 
1 17  SER n 
1 18  THR n 
1 19  ARG n 
1 20  VAL n 
1 21  LYS n 
1 22  LEU n 
1 23  LEU n 
1 24  GLU n 
1 25  GLU n 
1 26  LEU n 
1 27  ARG n 
1 28  TRP n 
1 29  ARG n 
1 30  SER n 
1 31  ILE n 
1 32  GLN n 
1 33  TYR n 
1 34  ALA n 
1 35  SER n 
1 36  ARG n 
1 37  GLY n 
1 38  GLU n 
1 39  ARG n 
1 40  HIS n 
1 41  SER n 
1 42  ALA n 
1 43  TYR n 
1 44  ASN n 
1 45  GLU n 
1 46  TRP n 
1 47  LYS n 
1 48  LYS n 
1 49  ALA n 
1 50  LEU n 
1 51  PHE n 
1 52  LYS n 
1 53  PRO n 
1 54  ALA n 
1 55  ASP n 
1 56  VAL n 
1 57  ILE n 
1 58  LEU n 
1 59  ASP n 
1 60  PRO n 
1 61  LYS n 
1 62  THR n 
1 63  ALA n 
1 64  ASN n 
1 65  PRO n 
1 66  ILE n 
1 67  LEU n 
1 68  LEU n 
1 69  VAL n 
1 70  SER n 
1 71  GLU n 
1 72  ASP n 
1 73  GLN n 
1 74  ARG n 
1 75  SER n 
1 76  VAL n 
1 77  GLN n 
1 78  ARG n 
1 79  ALA n 
1 80  LYS n 
1 81  GLU n 
1 82  PRO n 
1 83  GLN n 
1 84  ASP n 
1 85  LEU n 
1 86  PRO n 
1 87  ASP n 
1 88  ASN n 
1 89  PRO n 
1 90  GLU n 
1 91  ARG n 
1 92  PHE n 
1 93  ASN n 
1 94  TRP n 
1 95  HIS n 
1 96  TYR n 
1 97  CYS n 
1 98  VAL n 
1 99  LEU n 
1 100 GLY n 
1 101 CYS n 
1 102 GLU n 
1 103 SER n 
1 104 PHE n 
1 105 ILE n 
1 106 SER n 
1 107 GLY n 
1 108 ARG n 
1 109 HIS n 
1 110 TYR n 
1 111 TRP n 
1 112 GLU n 
1 113 VAL n 
1 114 GLU n 
1 115 VAL n 
1 116 GLY n 
1 117 ASP n 
1 118 ARG n 
1 119 LYS n 
1 120 GLU n 
1 121 TRP n 
1 122 HIS n 
1 123 ILE n 
1 124 GLY n 
1 125 VAL n 
1 126 CYS n 
1 127 SER n 
1 128 LYS n 
1 129 ASN n 
1 130 VAL n 
1 131 GLN n 
1 132 ARG n 
1 133 LYS n 
1 134 GLY n 
1 135 TRP n 
1 136 VAL n 
1 137 LYS n 
1 138 MET n 
1 139 THR n 
1 140 PRO n 
1 141 GLU n 
1 142 ASN n 
1 143 GLY n 
1 144 PHE n 
1 145 TRP n 
1 146 THR n 
1 147 MET n 
1 148 GLY n 
1 149 LEU n 
1 150 THR n 
1 151 ASP n 
1 152 GLY n 
1 153 ASN n 
1 154 LYS n 
1 155 TYR n 
1 156 ARG n 
1 157 THR n 
1 158 LEU n 
1 159 THR n 
1 160 GLU n 
1 161 PRO n 
1 162 ARG n 
1 163 THR n 
1 164 ASN n 
1 165 LEU n 
1 166 LYS n 
1 167 LEU n 
1 168 PRO n 
1 169 LYS n 
1 170 THR n 
1 171 PRO n 
1 172 LYS n 
1 173 LYS n 
1 174 VAL n 
1 175 GLY n 
1 176 VAL n 
1 177 PHE n 
1 178 LEU n 
1 179 ASP n 
1 180 TYR n 
1 181 GLU n 
1 182 THR n 
1 183 GLY n 
1 184 ASP n 
1 185 ILE n 
1 186 SER n 
1 187 PHE n 
1 188 TYR n 
1 189 ASN n 
1 190 ALA n 
1 191 VAL n 
1 192 ASP n 
1 193 GLY n 
1 194 SER n 
1 195 HIS n 
1 196 ILE n 
1 197 HIS n 
1 198 THR n 
1 199 PHE n 
1 200 LEU n 
1 201 ASP n 
1 202 VAL n 
1 203 SER n 
1 204 PHE n 
1 205 SER n 
1 206 GLU n 
1 207 ALA n 
1 208 LEU n 
1 209 TYR n 
1 210 PRO n 
1 211 VAL n 
1 212 PHE n 
1 213 ARG n 
1 214 ILE n 
1 215 LEU n 
1 216 THR n 
1 217 LEU n 
1 218 GLU n 
1 219 PRO n 
1 220 THR n 
1 221 ALA n 
1 222 LEU n 
1 223 THR n 
1 224 ILE n 
1 225 CYS n 
1 226 PRO n 
1 227 ALA n 
2 1   TRP n 
2 2   ILE n 
2 3   ASN n 
2 4   LYS n 
2 5   LEU n 
2 6   GLN n 
2 7   LYS n 
2 8   GLU n 
2 9   LYS n 
2 10  LYS n 
2 11  ILE n 
2 12  LEU n 
2 13  SER n 
2 14  GLY n 
2 15  GLU n 
2 16  LYS n 
2 17  GLU n 
2 18  PHE n 
2 19  GLU n 
2 20  ARG n 
2 21  GLU n 
2 22  THR n 
2 23  ARG n 
2 24  GLU n 
2 25  ILE n 
2 26  ALA n 
2 27  LEU n 
2 28  LYS n 
2 29  GLU n 
2 30  LEU n 
2 31  GLU n 
2 32  LYS n 
2 33  GLU n 
2 34  ARG n 
2 35  VAL n 
2 36  GLN n 
2 37  LYS n 
2 38  GLU n 
2 39  GLU n 
2 40  GLU n 
2 41  LEU n 
2 42  GLN n 
2 43  VAL n 
2 44  LYS n 
2 45  GLU n 
2 46  LYS n 
2 47  LEU n 
2 48  GLN n 
2 49  GLU n 
2 50  GLU n 
2 51  LEU n 
2 52  ARG n 
2 53  TRP n 
2 54  ARG n 
2 55  ARG n 
2 56  THR n 
2 57  PHE n 
2 58  LEU n 
2 59  HIS n 
2 60  ALA n 
2 61  VAL n 
2 62  ASP n 
2 63  VAL n 
2 64  VAL n 
2 65  LEU n 
2 66  ASP n 
2 67  PRO n 
2 68  ASP n 
2 69  THR n 
2 70  ALA n 
2 71  HIS n 
2 72  PRO n 
2 73  ASP n 
2 74  LEU n 
2 75  PHE n 
2 76  LEU n 
2 77  SER n 
2 78  GLU n 
2 79  ASP n 
2 80  ARG n 
2 81  ARG n 
2 82  SER n 
2 83  VAL n 
2 84  ARG n 
2 85  ARG n 
2 86  CYS n 
2 87  PRO n 
2 88  PHE n 
2 89  ARG n 
2 90  HIS n 
2 91  LEU n 
2 92  GLY n 
2 93  GLU n 
2 94  SER n 
2 95  VAL n 
2 96  PRO n 
2 97  ASP n 
2 98  ASN n 
2 99  PRO n 
2 100 GLU n 
2 101 ARG n 
2 102 PHE n 
2 103 ASP n 
2 104 SER n 
2 105 GLN n 
2 106 PRO n 
2 107 CYS n 
2 108 VAL n 
2 109 LEU n 
2 110 GLY n 
2 111 ARG n 
2 112 GLU n 
2 113 SER n 
2 114 PHE n 
2 115 ALA n 
2 116 SER n 
2 117 GLY n 
2 118 LYS n 
2 119 HIS n 
2 120 TYR n 
2 121 TRP n 
2 122 GLU n 
2 123 VAL n 
2 124 GLU n 
2 125 VAL n 
2 126 GLU n 
2 127 ASN n 
2 128 VAL n 
2 129 ILE n 
2 130 GLU n 
2 131 TRP n 
2 132 THR n 
2 133 VAL n 
2 134 GLY n 
2 135 VAL n 
2 136 CYS n 
2 137 ARG n 
2 138 ASP n 
2 139 SER n 
2 140 VAL n 
2 141 GLU n 
2 142 ARG n 
2 143 LYS n 
2 144 GLY n 
2 145 GLU n 
2 146 VAL n 
2 147 LEU n 
2 148 LEU n 
2 149 ILE n 
2 150 PRO n 
2 151 GLN n 
2 152 ASN n 
2 153 GLY n 
2 154 PHE n 
2 155 TRP n 
2 156 THR n 
2 157 LEU n 
2 158 GLU n 
2 159 MET n 
2 160 HIS n 
2 161 LYS n 
2 162 GLY n 
2 163 GLN n 
2 164 TYR n 
2 165 ARG n 
2 166 ALA n 
2 167 VAL n 
2 168 SER n 
2 169 SER n 
2 170 PRO n 
2 171 ASP n 
2 172 ARG n 
2 173 ILE n 
2 174 LEU n 
2 175 PRO n 
2 176 LEU n 
2 177 LYS n 
2 178 GLU n 
2 179 SER n 
2 180 LEU n 
2 181 CYS n 
2 182 ARG n 
2 183 VAL n 
2 184 GLY n 
2 185 VAL n 
2 186 PHE n 
2 187 LEU n 
2 188 ASP n 
2 189 TYR n 
2 190 GLU n 
2 191 ALA n 
2 192 GLY n 
2 193 ASP n 
2 194 VAL n 
2 195 SER n 
2 196 PHE n 
2 197 TYR n 
2 198 ASN n 
2 199 MET n 
2 200 ARG n 
2 201 ASP n 
2 202 ARG n 
2 203 SER n 
2 204 HIS n 
2 205 ILE n 
2 206 TYR n 
2 207 THR n 
2 208 CYS n 
2 209 PRO n 
2 210 ARG n 
2 211 SER n 
2 212 ALA n 
2 213 PHE n 
2 214 SER n 
2 215 VAL n 
2 216 PRO n 
2 217 VAL n 
2 218 ARG n 
2 219 PRO n 
2 220 PHE n 
2 221 PHE n 
2 222 ARG n 
2 223 LEU n 
2 224 GLY n 
2 225 CYS n 
2 226 GLU n 
2 227 ASP n 
2 228 SER n 
2 229 PRO n 
2 230 ILE n 
2 231 PHE n 
2 232 ILE n 
2 233 CYS n 
2 234 PRO n 
2 235 ALA n 
2 236 LEU n 
2 237 THR n 
2 238 GLY n 
2 239 ALA n 
2 240 ASN n 
2 241 GLY n 
2 242 VAL n 
2 243 THR n 
2 244 VAL n 
2 245 PRO n 
2 246 GLU n 
2 247 GLU n 
2 248 GLY n 
2 249 LEU n 
2 250 THR n 
2 251 LEU n 
2 252 HIS n 
2 253 ARG n 
2 254 VAL n 
2 255 GLY n 
2 256 THR n 
2 257 HIS n 
2 258 GLN n 
2 259 SER n 
2 260 LEU n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 227 human ? 'BTN3A1, BTF5'        ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? human 
'Homo sapiens' 9606 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 260 human ? 'BTN2A1, BT2.1, BTF1' ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? human 
'Homo sapiens' 9606 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                                ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE                               ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE                             ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                        ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE                               ? 'C3 H7 N O2 S'   121.158 
EIP non-polymer         . '4-HYDROXY-3-METHYL BUTYL DIPHOSPHATE' ? 'C5 H14 O8 P2'   264.107 
GLN 'L-peptide linking' y GLUTAMINE                              ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                        ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE                                ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE                              ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE                             ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE                                ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE                                 ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE                             ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE                          ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE                                ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE                                 ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE                              ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                             ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE                               ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE                                 ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   GLU 1   258 258 GLU GLU C . n 
A 1 2   GLN 2   259 259 GLN GLN C . n 
A 1 3   GLU 3   260 260 GLU GLU C . n 
A 1 4   LEU 4   261 261 LEU LEU C . n 
A 1 5   ARG 5   262 262 ARG ARG C . n 
A 1 6   GLU 6   263 263 GLU GLU C . n 
A 1 7   MET 7   264 264 MET MET C . n 
A 1 8   ALA 8   265 265 ALA ALA C . n 
A 1 9   TRP 9   266 266 TRP TRP C . n 
A 1 10  SER 10  267 267 SER SER C . n 
A 1 11  THR 11  268 268 THR THR C . n 
A 1 12  MET 12  269 269 MET MET C . n 
A 1 13  LYS 13  270 270 LYS LYS C . n 
A 1 14  GLN 14  271 271 GLN GLN C . n 
A 1 15  GLU 15  272 272 GLU GLU C . n 
A 1 16  GLN 16  273 273 GLN GLN C . n 
A 1 17  SER 17  274 274 SER SER C . n 
A 1 18  THR 18  275 275 THR THR C . n 
A 1 19  ARG 19  276 276 ARG ARG C . n 
A 1 20  VAL 20  277 277 VAL VAL C . n 
A 1 21  LYS 21  278 278 LYS LYS C . n 
A 1 22  LEU 22  279 279 LEU LEU C . n 
A 1 23  LEU 23  280 280 LEU LEU C . n 
A 1 24  GLU 24  281 281 GLU GLU C . n 
A 1 25  GLU 25  282 282 GLU GLU C . n 
A 1 26  LEU 26  283 283 LEU LEU C . n 
A 1 27  ARG 27  284 284 ARG ARG C . n 
A 1 28  TRP 28  285 285 TRP TRP C . n 
A 1 29  ARG 29  286 286 ARG ARG C . n 
A 1 30  SER 30  287 287 SER SER C . n 
A 1 31  ILE 31  288 288 ILE ILE C . n 
A 1 32  GLN 32  289 289 GLN GLN C . n 
A 1 33  TYR 33  290 290 TYR TYR C . n 
A 1 34  ALA 34  291 291 ALA ALA C . n 
A 1 35  SER 35  292 292 SER SER C . n 
A 1 36  ARG 36  293 293 ARG ARG C . n 
A 1 37  GLY 37  294 294 GLY GLY C . n 
A 1 38  GLU 38  295 295 GLU GLU C . n 
A 1 39  ARG 39  296 296 ARG ARG C . n 
A 1 40  HIS 40  297 297 HIS HIS C . n 
A 1 41  SER 41  298 298 SER SER C . n 
A 1 42  ALA 42  299 299 ALA ALA C . n 
A 1 43  TYR 43  300 300 TYR TYR C . n 
A 1 44  ASN 44  301 301 ASN ASN C . n 
A 1 45  GLU 45  302 302 GLU GLU C . n 
A 1 46  TRP 46  303 303 TRP TRP C . n 
A 1 47  LYS 47  304 304 LYS LYS C . n 
A 1 48  LYS 48  305 305 LYS LYS C . n 
A 1 49  ALA 49  306 306 ALA ALA C . n 
A 1 50  LEU 50  307 307 LEU LEU C . n 
A 1 51  PHE 51  308 308 PHE PHE C . n 
A 1 52  LYS 52  309 309 LYS LYS C . n 
A 1 53  PRO 53  310 310 PRO PRO C . n 
A 1 54  ALA 54  311 311 ALA ALA C . n 
A 1 55  ASP 55  312 312 ASP ASP C . n 
A 1 56  VAL 56  313 313 VAL VAL C . n 
A 1 57  ILE 57  314 314 ILE ILE C . n 
A 1 58  LEU 58  315 315 LEU LEU C . n 
A 1 59  ASP 59  316 316 ASP ASP C . n 
A 1 60  PRO 60  317 317 PRO PRO C . n 
A 1 61  LYS 61  318 318 LYS LYS C . n 
A 1 62  THR 62  319 319 THR THR C . n 
A 1 63  ALA 63  320 320 ALA ALA C . n 
A 1 64  ASN 64  321 321 ASN ASN C . n 
A 1 65  PRO 65  322 322 PRO PRO C . n 
A 1 66  ILE 66  323 323 ILE ILE C . n 
A 1 67  LEU 67  324 324 LEU LEU C . n 
A 1 68  LEU 68  325 325 LEU LEU C . n 
A 1 69  VAL 69  326 326 VAL VAL C . n 
A 1 70  SER 70  327 327 SER SER C . n 
A 1 71  GLU 71  328 328 GLU GLU C . n 
A 1 72  ASP 72  329 329 ASP ASP C . n 
A 1 73  GLN 73  330 330 GLN GLN C . n 
A 1 74  ARG 74  331 331 ARG ARG C . n 
A 1 75  SER 75  332 332 SER SER C . n 
A 1 76  VAL 76  333 333 VAL VAL C . n 
A 1 77  GLN 77  334 334 GLN GLN C . n 
A 1 78  ARG 78  335 335 ARG ARG C . n 
A 1 79  ALA 79  336 336 ALA ALA C . n 
A 1 80  LYS 80  337 337 LYS LYS C . n 
A 1 81  GLU 81  338 338 GLU GLU C . n 
A 1 82  PRO 82  339 339 PRO PRO C . n 
A 1 83  GLN 83  340 340 GLN GLN C . n 
A 1 84  ASP 84  341 341 ASP ASP C . n 
A 1 85  LEU 85  342 342 LEU LEU C . n 
A 1 86  PRO 86  343 343 PRO PRO C . n 
A 1 87  ASP 87  344 344 ASP ASP C . n 
A 1 88  ASN 88  345 345 ASN ASN C . n 
A 1 89  PRO 89  346 346 PRO PRO C . n 
A 1 90  GLU 90  347 347 GLU GLU C . n 
A 1 91  ARG 91  348 348 ARG ARG C . n 
A 1 92  PHE 92  349 349 PHE PHE C . n 
A 1 93  ASN 93  350 350 ASN ASN C . n 
A 1 94  TRP 94  351 351 TRP TRP C . n 
A 1 95  HIS 95  352 352 HIS HIS C . n 
A 1 96  TYR 96  353 353 TYR TYR C . n 
A 1 97  CYS 97  354 354 CYS CYS C . n 
A 1 98  VAL 98  355 355 VAL VAL C . n 
A 1 99  LEU 99  356 356 LEU LEU C . n 
A 1 100 GLY 100 357 357 GLY GLY C . n 
A 1 101 CYS 101 358 358 CYS CYS C . n 
A 1 102 GLU 102 359 359 GLU GLU C . n 
A 1 103 SER 103 360 360 SER SER C . n 
A 1 104 PHE 104 361 361 PHE PHE C . n 
A 1 105 ILE 105 362 362 ILE ILE C . n 
A 1 106 SER 106 363 363 SER SER C . n 
A 1 107 GLY 107 364 364 GLY GLY C . n 
A 1 108 ARG 108 365 365 ARG ARG C . n 
A 1 109 HIS 109 366 366 HIS HIS C . n 
A 1 110 TYR 110 367 367 TYR TYR C . n 
A 1 111 TRP 111 368 368 TRP TRP C . n 
A 1 112 GLU 112 369 369 GLU GLU C . n 
A 1 113 VAL 113 370 370 VAL VAL C . n 
A 1 114 GLU 114 371 371 GLU GLU C . n 
A 1 115 VAL 115 372 372 VAL VAL C . n 
A 1 116 GLY 116 373 373 GLY GLY C . n 
A 1 117 ASP 117 374 374 ASP ASP C . n 
A 1 118 ARG 118 375 375 ARG ARG C . n 
A 1 119 LYS 119 376 376 LYS LYS C . n 
A 1 120 GLU 120 377 377 GLU GLU C . n 
A 1 121 TRP 121 378 378 TRP TRP C . n 
A 1 122 HIS 122 379 379 HIS HIS C . n 
A 1 123 ILE 123 380 380 ILE ILE C . n 
A 1 124 GLY 124 381 381 GLY GLY C . n 
A 1 125 VAL 125 382 382 VAL VAL C . n 
A 1 126 CYS 126 383 383 CYS CYS C . n 
A 1 127 SER 127 384 384 SER SER C . n 
A 1 128 LYS 128 385 385 LYS LYS C . n 
A 1 129 ASN 129 386 386 ASN ASN C . n 
A 1 130 VAL 130 387 387 VAL VAL C . n 
A 1 131 GLN 131 388 388 GLN GLN C . n 
A 1 132 ARG 132 389 389 ARG ARG C . n 
A 1 133 LYS 133 390 390 LYS LYS C . n 
A 1 134 GLY 134 391 391 GLY GLY C . n 
A 1 135 TRP 135 392 392 TRP TRP C . n 
A 1 136 VAL 136 393 393 VAL VAL C . n 
A 1 137 LYS 137 394 394 LYS LYS C . n 
A 1 138 MET 138 395 395 MET MET C . n 
A 1 139 THR 139 396 396 THR THR C . n 
A 1 140 PRO 140 397 397 PRO PRO C . n 
A 1 141 GLU 141 398 398 GLU GLU C . n 
A 1 142 ASN 142 399 399 ASN ASN C . n 
A 1 143 GLY 143 400 400 GLY GLY C . n 
A 1 144 PHE 144 401 401 PHE PHE C . n 
A 1 145 TRP 145 402 402 TRP TRP C . n 
A 1 146 THR 146 403 403 THR THR C . n 
A 1 147 MET 147 404 404 MET MET C . n 
A 1 148 GLY 148 405 405 GLY GLY C . n 
A 1 149 LEU 149 406 406 LEU LEU C . n 
A 1 150 THR 150 407 407 THR THR C . n 
A 1 151 ASP 151 408 408 ASP ASP C . n 
A 1 152 GLY 152 409 409 GLY GLY C . n 
A 1 153 ASN 153 410 410 ASN ASN C . n 
A 1 154 LYS 154 411 411 LYS LYS C . n 
A 1 155 TYR 155 412 412 TYR TYR C . n 
A 1 156 ARG 156 413 413 ARG ARG C . n 
A 1 157 THR 157 414 414 THR THR C . n 
A 1 158 LEU 158 415 415 LEU LEU C . n 
A 1 159 THR 159 416 416 THR THR C . n 
A 1 160 GLU 160 417 417 GLU GLU C . n 
A 1 161 PRO 161 418 418 PRO PRO C . n 
A 1 162 ARG 162 419 419 ARG ARG C . n 
A 1 163 THR 163 420 420 THR THR C . n 
A 1 164 ASN 164 421 421 ASN ASN C . n 
A 1 165 LEU 165 422 422 LEU LEU C . n 
A 1 166 LYS 166 423 423 LYS LYS C . n 
A 1 167 LEU 167 424 424 LEU LEU C . n 
A 1 168 PRO 168 425 425 PRO PRO C . n 
A 1 169 LYS 169 426 426 LYS LYS C . n 
A 1 170 THR 170 427 427 THR THR C . n 
A 1 171 PRO 171 428 428 PRO PRO C . n 
A 1 172 LYS 172 429 429 LYS LYS C . n 
A 1 173 LYS 173 430 430 LYS LYS C . n 
A 1 174 VAL 174 431 431 VAL VAL C . n 
A 1 175 GLY 175 432 432 GLY GLY C . n 
A 1 176 VAL 176 433 433 VAL VAL C . n 
A 1 177 PHE 177 434 434 PHE PHE C . n 
A 1 178 LEU 178 435 435 LEU LEU C . n 
A 1 179 ASP 179 436 436 ASP ASP C . n 
A 1 180 TYR 180 437 437 TYR TYR C . n 
A 1 181 GLU 181 438 438 GLU GLU C . n 
A 1 182 THR 182 439 439 THR THR C . n 
A 1 183 GLY 183 440 440 GLY GLY C . n 
A 1 184 ASP 184 441 441 ASP ASP C . n 
A 1 185 ILE 185 442 442 ILE ILE C . n 
A 1 186 SER 186 443 443 SER SER C . n 
A 1 187 PHE 187 444 444 PHE PHE C . n 
A 1 188 TYR 188 445 445 TYR TYR C . n 
A 1 189 ASN 189 446 446 ASN ASN C . n 
A 1 190 ALA 190 447 447 ALA ALA C . n 
A 1 191 VAL 191 448 448 VAL VAL C . n 
A 1 192 ASP 192 449 449 ASP ASP C . n 
A 1 193 GLY 193 450 450 GLY GLY C . n 
A 1 194 SER 194 451 451 SER SER C . n 
A 1 195 HIS 195 452 452 HIS HIS C . n 
A 1 196 ILE 196 453 453 ILE ILE C . n 
A 1 197 HIS 197 454 454 HIS HIS C . n 
A 1 198 THR 198 455 455 THR THR C . n 
A 1 199 PHE 199 456 456 PHE PHE C . n 
A 1 200 LEU 200 457 457 LEU LEU C . n 
A 1 201 ASP 201 458 458 ASP ASP C . n 
A 1 202 VAL 202 459 459 VAL VAL C . n 
A 1 203 SER 203 460 460 SER SER C . n 
A 1 204 PHE 204 461 461 PHE PHE C . n 
A 1 205 SER 205 462 462 SER SER C . n 
A 1 206 GLU 206 463 463 GLU GLU C . n 
A 1 207 ALA 207 464 464 ALA ALA C . n 
A 1 208 LEU 208 465 465 LEU LEU C . n 
A 1 209 TYR 209 466 466 TYR TYR C . n 
A 1 210 PRO 210 467 467 PRO PRO C . n 
A 1 211 VAL 211 468 468 VAL VAL C . n 
A 1 212 PHE 212 469 469 PHE PHE C . n 
A 1 213 ARG 213 470 470 ARG ARG C . n 
A 1 214 ILE 214 471 471 ILE ILE C . n 
A 1 215 LEU 215 472 472 LEU LEU C . n 
A 1 216 THR 216 473 473 THR THR C . n 
A 1 217 LEU 217 474 474 LEU LEU C . n 
A 1 218 GLU 218 475 475 GLU GLU C . n 
A 1 219 PRO 219 476 476 PRO PRO C . n 
A 1 220 THR 220 477 477 THR THR C . n 
A 1 221 ALA 221 478 478 ALA ALA C . n 
A 1 222 LEU 222 479 479 LEU LEU C . n 
A 1 223 THR 223 480 480 THR THR C . n 
A 1 224 ILE 224 481 481 ILE ILE C . n 
A 1 225 CYS 225 482 482 CYS CYS C . n 
A 1 226 PRO 226 483 483 PRO PRO C . n 
A 1 227 ALA 227 484 484 ALA ALA C . n 
B 1 1   GLU 1   258 ?   ?   ?   D . n 
B 1 2   GLN 2   259 ?   ?   ?   D . n 
B 1 3   GLU 3   260 ?   ?   ?   D . n 
B 1 4   LEU 4   261 ?   ?   ?   D . n 
B 1 5   ARG 5   262 ?   ?   ?   D . n 
B 1 6   GLU 6   263 ?   ?   ?   D . n 
B 1 7   MET 7   264 ?   ?   ?   D . n 
B 1 8   ALA 8   265 ?   ?   ?   D . n 
B 1 9   TRP 9   266 266 TRP TRP D . n 
B 1 10  SER 10  267 267 SER SER D . n 
B 1 11  THR 11  268 268 THR THR D . n 
B 1 12  MET 12  269 269 MET MET D . n 
B 1 13  LYS 13  270 270 LYS LYS D . n 
B 1 14  GLN 14  271 271 GLN GLN D . n 
B 1 15  GLU 15  272 272 GLU GLU D . n 
B 1 16  GLN 16  273 273 GLN GLN D . n 
B 1 17  SER 17  274 274 SER SER D . n 
B 1 18  THR 18  275 275 THR THR D . n 
B 1 19  ARG 19  276 276 ARG ARG D . n 
B 1 20  VAL 20  277 277 VAL VAL D . n 
B 1 21  LYS 21  278 278 LYS LYS D . n 
B 1 22  LEU 22  279 279 LEU LEU D . n 
B 1 23  LEU 23  280 280 LEU LEU D . n 
B 1 24  GLU 24  281 281 GLU GLU D . n 
B 1 25  GLU 25  282 282 GLU GLU D . n 
B 1 26  LEU 26  283 283 LEU LEU D . n 
B 1 27  ARG 27  284 284 ARG ARG D . n 
B 1 28  TRP 28  285 285 TRP TRP D . n 
B 1 29  ARG 29  286 286 ARG ARG D . n 
B 1 30  SER 30  287 287 SER SER D . n 
B 1 31  ILE 31  288 288 ILE ILE D . n 
B 1 32  GLN 32  289 289 GLN GLN D . n 
B 1 33  TYR 33  290 290 TYR TYR D . n 
B 1 34  ALA 34  291 291 ALA ALA D . n 
B 1 35  SER 35  292 292 SER SER D . n 
B 1 36  ARG 36  293 293 ARG ARG D . n 
B 1 37  GLY 37  294 294 GLY GLY D . n 
B 1 38  GLU 38  295 295 GLU GLU D . n 
B 1 39  ARG 39  296 296 ARG ARG D . n 
B 1 40  HIS 40  297 297 HIS HIS D . n 
B 1 41  SER 41  298 298 SER SER D . n 
B 1 42  ALA 42  299 299 ALA ALA D . n 
B 1 43  TYR 43  300 300 TYR TYR D . n 
B 1 44  ASN 44  301 301 ASN ASN D . n 
B 1 45  GLU 45  302 302 GLU GLU D . n 
B 1 46  TRP 46  303 303 TRP TRP D . n 
B 1 47  LYS 47  304 304 LYS LYS D . n 
B 1 48  LYS 48  305 305 LYS LYS D . n 
B 1 49  ALA 49  306 306 ALA ALA D . n 
B 1 50  LEU 50  307 307 LEU LEU D . n 
B 1 51  PHE 51  308 308 PHE PHE D . n 
B 1 52  LYS 52  309 309 LYS LYS D . n 
B 1 53  PRO 53  310 310 PRO PRO D . n 
B 1 54  ALA 54  311 311 ALA ALA D . n 
B 1 55  ASP 55  312 312 ASP ASP D . n 
B 1 56  VAL 56  313 313 VAL VAL D . n 
B 1 57  ILE 57  314 314 ILE ILE D . n 
B 1 58  LEU 58  315 315 LEU LEU D . n 
B 1 59  ASP 59  316 316 ASP ASP D . n 
B 1 60  PRO 60  317 317 PRO PRO D . n 
B 1 61  LYS 61  318 318 LYS LYS D . n 
B 1 62  THR 62  319 319 THR THR D . n 
B 1 63  ALA 63  320 320 ALA ALA D . n 
B 1 64  ASN 64  321 321 ASN ASN D . n 
B 1 65  PRO 65  322 322 PRO PRO D . n 
B 1 66  ILE 66  323 323 ILE ILE D . n 
B 1 67  LEU 67  324 324 LEU LEU D . n 
B 1 68  LEU 68  325 325 LEU LEU D . n 
B 1 69  VAL 69  326 326 VAL VAL D . n 
B 1 70  SER 70  327 327 SER SER D . n 
B 1 71  GLU 71  328 328 GLU GLU D . n 
B 1 72  ASP 72  329 329 ASP ASP D . n 
B 1 73  GLN 73  330 330 GLN GLN D . n 
B 1 74  ARG 74  331 331 ARG ARG D . n 
B 1 75  SER 75  332 332 SER SER D . n 
B 1 76  VAL 76  333 333 VAL VAL D . n 
B 1 77  GLN 77  334 334 GLN GLN D . n 
B 1 78  ARG 78  335 335 ARG ARG D . n 
B 1 79  ALA 79  336 336 ALA ALA D . n 
B 1 80  LYS 80  337 337 LYS LYS D . n 
B 1 81  GLU 81  338 338 GLU GLU D . n 
B 1 82  PRO 82  339 339 PRO PRO D . n 
B 1 83  GLN 83  340 340 GLN GLN D . n 
B 1 84  ASP 84  341 341 ASP ASP D . n 
B 1 85  LEU 85  342 342 LEU LEU D . n 
B 1 86  PRO 86  343 343 PRO PRO D . n 
B 1 87  ASP 87  344 344 ASP ASP D . n 
B 1 88  ASN 88  345 345 ASN ASN D . n 
B 1 89  PRO 89  346 346 PRO PRO D . n 
B 1 90  GLU 90  347 347 GLU GLU D . n 
B 1 91  ARG 91  348 348 ARG ARG D . n 
B 1 92  PHE 92  349 349 PHE PHE D . n 
B 1 93  ASN 93  350 350 ASN ASN D . n 
B 1 94  TRP 94  351 351 TRP TRP D . n 
B 1 95  HIS 95  352 352 HIS HIS D . n 
B 1 96  TYR 96  353 353 TYR TYR D . n 
B 1 97  CYS 97  354 354 CYS CYS D . n 
B 1 98  VAL 98  355 355 VAL VAL D . n 
B 1 99  LEU 99  356 356 LEU LEU D . n 
B 1 100 GLY 100 357 357 GLY GLY D . n 
B 1 101 CYS 101 358 358 CYS CYS D . n 
B 1 102 GLU 102 359 359 GLU GLU D . n 
B 1 103 SER 103 360 360 SER SER D . n 
B 1 104 PHE 104 361 361 PHE PHE D . n 
B 1 105 ILE 105 362 362 ILE ILE D . n 
B 1 106 SER 106 363 363 SER SER D . n 
B 1 107 GLY 107 364 364 GLY GLY D . n 
B 1 108 ARG 108 365 365 ARG ARG D . n 
B 1 109 HIS 109 366 366 HIS HIS D . n 
B 1 110 TYR 110 367 367 TYR TYR D . n 
B 1 111 TRP 111 368 368 TRP TRP D . n 
B 1 112 GLU 112 369 369 GLU GLU D . n 
B 1 113 VAL 113 370 370 VAL VAL D . n 
B 1 114 GLU 114 371 371 GLU GLU D . n 
B 1 115 VAL 115 372 372 VAL VAL D . n 
B 1 116 GLY 116 373 373 GLY GLY D . n 
B 1 117 ASP 117 374 374 ASP ASP D . n 
B 1 118 ARG 118 375 375 ARG ARG D . n 
B 1 119 LYS 119 376 376 LYS LYS D . n 
B 1 120 GLU 120 377 377 GLU GLU D . n 
B 1 121 TRP 121 378 378 TRP TRP D . n 
B 1 122 HIS 122 379 379 HIS HIS D . n 
B 1 123 ILE 123 380 380 ILE ILE D . n 
B 1 124 GLY 124 381 381 GLY GLY D . n 
B 1 125 VAL 125 382 382 VAL VAL D . n 
B 1 126 CYS 126 383 383 CYS CYS D . n 
B 1 127 SER 127 384 384 SER SER D . n 
B 1 128 LYS 128 385 385 LYS LYS D . n 
B 1 129 ASN 129 386 386 ASN ASN D . n 
B 1 130 VAL 130 387 387 VAL VAL D . n 
B 1 131 GLN 131 388 388 GLN GLN D . n 
B 1 132 ARG 132 389 389 ARG ARG D . n 
B 1 133 LYS 133 390 390 LYS LYS D . n 
B 1 134 GLY 134 391 391 GLY GLY D . n 
B 1 135 TRP 135 392 392 TRP TRP D . n 
B 1 136 VAL 136 393 393 VAL VAL D . n 
B 1 137 LYS 137 394 394 LYS LYS D . n 
B 1 138 MET 138 395 395 MET MET D . n 
B 1 139 THR 139 396 396 THR THR D . n 
B 1 140 PRO 140 397 397 PRO PRO D . n 
B 1 141 GLU 141 398 398 GLU GLU D . n 
B 1 142 ASN 142 399 399 ASN ASN D . n 
B 1 143 GLY 143 400 400 GLY GLY D . n 
B 1 144 PHE 144 401 401 PHE PHE D . n 
B 1 145 TRP 145 402 402 TRP TRP D . n 
B 1 146 THR 146 403 403 THR THR D . n 
B 1 147 MET 147 404 404 MET MET D . n 
B 1 148 GLY 148 405 405 GLY GLY D . n 
B 1 149 LEU 149 406 406 LEU LEU D . n 
B 1 150 THR 150 407 407 THR THR D . n 
B 1 151 ASP 151 408 408 ASP ASP D . n 
B 1 152 GLY 152 409 409 GLY GLY D . n 
B 1 153 ASN 153 410 410 ASN ASN D . n 
B 1 154 LYS 154 411 411 LYS LYS D . n 
B 1 155 TYR 155 412 412 TYR TYR D . n 
B 1 156 ARG 156 413 413 ARG ARG D . n 
B 1 157 THR 157 414 414 THR THR D . n 
B 1 158 LEU 158 415 415 LEU LEU D . n 
B 1 159 THR 159 416 416 THR THR D . n 
B 1 160 GLU 160 417 417 GLU GLU D . n 
B 1 161 PRO 161 418 418 PRO PRO D . n 
B 1 162 ARG 162 419 419 ARG ARG D . n 
B 1 163 THR 163 420 420 THR THR D . n 
B 1 164 ASN 164 421 421 ASN ASN D . n 
B 1 165 LEU 165 422 422 LEU LEU D . n 
B 1 166 LYS 166 423 423 LYS LYS D . n 
B 1 167 LEU 167 424 424 LEU LEU D . n 
B 1 168 PRO 168 425 425 PRO PRO D . n 
B 1 169 LYS 169 426 426 LYS LYS D . n 
B 1 170 THR 170 427 427 THR THR D . n 
B 1 171 PRO 171 428 428 PRO PRO D . n 
B 1 172 LYS 172 429 429 LYS LYS D . n 
B 1 173 LYS 173 430 430 LYS LYS D . n 
B 1 174 VAL 174 431 431 VAL VAL D . n 
B 1 175 GLY 175 432 432 GLY GLY D . n 
B 1 176 VAL 176 433 433 VAL VAL D . n 
B 1 177 PHE 177 434 434 PHE PHE D . n 
B 1 178 LEU 178 435 435 LEU LEU D . n 
B 1 179 ASP 179 436 436 ASP ASP D . n 
B 1 180 TYR 180 437 437 TYR TYR D . n 
B 1 181 GLU 181 438 438 GLU GLU D . n 
B 1 182 THR 182 439 439 THR THR D . n 
B 1 183 GLY 183 440 440 GLY GLY D . n 
B 1 184 ASP 184 441 441 ASP ASP D . n 
B 1 185 ILE 185 442 442 ILE ILE D . n 
B 1 186 SER 186 443 443 SER SER D . n 
B 1 187 PHE 187 444 444 PHE PHE D . n 
B 1 188 TYR 188 445 445 TYR TYR D . n 
B 1 189 ASN 189 446 446 ASN ASN D . n 
B 1 190 ALA 190 447 447 ALA ALA D . n 
B 1 191 VAL 191 448 448 VAL VAL D . n 
B 1 192 ASP 192 449 449 ASP ASP D . n 
B 1 193 GLY 193 450 450 GLY GLY D . n 
B 1 194 SER 194 451 451 SER SER D . n 
B 1 195 HIS 195 452 452 HIS HIS D . n 
B 1 196 ILE 196 453 453 ILE ILE D . n 
B 1 197 HIS 197 454 454 HIS HIS D . n 
B 1 198 THR 198 455 455 THR THR D . n 
B 1 199 PHE 199 456 456 PHE PHE D . n 
B 1 200 LEU 200 457 457 LEU LEU D . n 
B 1 201 ASP 201 458 458 ASP ASP D . n 
B 1 202 VAL 202 459 459 VAL VAL D . n 
B 1 203 SER 203 460 460 SER SER D . n 
B 1 204 PHE 204 461 461 PHE PHE D . n 
B 1 205 SER 205 462 462 SER SER D . n 
B 1 206 GLU 206 463 463 GLU GLU D . n 
B 1 207 ALA 207 464 464 ALA ALA D . n 
B 1 208 LEU 208 465 465 LEU LEU D . n 
B 1 209 TYR 209 466 466 TYR TYR D . n 
B 1 210 PRO 210 467 467 PRO PRO D . n 
B 1 211 VAL 211 468 468 VAL VAL D . n 
B 1 212 PHE 212 469 469 PHE PHE D . n 
B 1 213 ARG 213 470 470 ARG ARG D . n 
B 1 214 ILE 214 471 471 ILE ILE D . n 
B 1 215 LEU 215 472 472 LEU LEU D . n 
B 1 216 THR 216 473 473 THR THR D . n 
B 1 217 LEU 217 474 474 LEU LEU D . n 
B 1 218 GLU 218 475 475 GLU GLU D . n 
B 1 219 PRO 219 476 476 PRO PRO D . n 
B 1 220 THR 220 477 477 THR THR D . n 
B 1 221 ALA 221 478 478 ALA ALA D . n 
B 1 222 LEU 222 479 479 LEU LEU D . n 
B 1 223 THR 223 480 480 THR THR D . n 
B 1 224 ILE 224 481 481 ILE ILE D . n 
B 1 225 CYS 225 482 482 CYS CYS D . n 
B 1 226 PRO 226 483 483 PRO PRO D . n 
B 1 227 ALA 227 484 484 ALA ALA D . n 
C 2 1   TRP 1   240 240 TRP TRP G . n 
C 2 2   ILE 2   241 241 ILE ILE G . n 
C 2 3   ASN 3   242 242 ASN ASN G . n 
C 2 4   LYS 4   243 243 LYS LYS G . n 
C 2 5   LEU 5   244 244 LEU LEU G . n 
C 2 6   GLN 6   245 245 GLN GLN G . n 
C 2 7   LYS 7   246 246 LYS LYS G . n 
C 2 8   GLU 8   247 247 GLU GLU G . n 
C 2 9   LYS 9   248 248 LYS LYS G . n 
C 2 10  LYS 10  249 249 LYS LYS G . n 
C 2 11  ILE 11  250 250 ILE ILE G . n 
C 2 12  LEU 12  251 251 LEU LEU G . n 
C 2 13  SER 13  252 252 SER SER G . n 
C 2 14  GLY 14  253 253 GLY GLY G . n 
C 2 15  GLU 15  254 254 GLU GLU G . n 
C 2 16  LYS 16  255 255 LYS LYS G . n 
C 2 17  GLU 17  256 256 GLU GLU G . n 
C 2 18  PHE 18  257 257 PHE PHE G . n 
C 2 19  GLU 19  258 258 GLU GLU G . n 
C 2 20  ARG 20  259 259 ARG ARG G . n 
C 2 21  GLU 21  260 260 GLU GLU G . n 
C 2 22  THR 22  261 261 THR THR G . n 
C 2 23  ARG 23  262 262 ARG ARG G . n 
C 2 24  GLU 24  263 263 GLU GLU G . n 
C 2 25  ILE 25  264 264 ILE ILE G . n 
C 2 26  ALA 26  265 265 ALA ALA G . n 
C 2 27  LEU 27  266 266 LEU LEU G . n 
C 2 28  LYS 28  267 267 LYS LYS G . n 
C 2 29  GLU 29  268 268 GLU GLU G . n 
C 2 30  LEU 30  269 269 LEU LEU G . n 
C 2 31  GLU 31  270 270 GLU GLU G . n 
C 2 32  LYS 32  271 271 LYS LYS G . n 
C 2 33  GLU 33  272 272 GLU GLU G . n 
C 2 34  ARG 34  273 273 ARG ARG G . n 
C 2 35  VAL 35  274 274 VAL VAL G . n 
C 2 36  GLN 36  275 275 GLN GLN G . n 
C 2 37  LYS 37  276 276 LYS LYS G . n 
C 2 38  GLU 38  277 277 GLU GLU G . n 
C 2 39  GLU 39  278 278 GLU GLU G . n 
C 2 40  GLU 40  279 279 GLU GLU G . n 
C 2 41  LEU 41  280 280 LEU LEU G . n 
C 2 42  GLN 42  281 281 GLN GLN G . n 
C 2 43  VAL 43  282 282 VAL VAL G . n 
C 2 44  LYS 44  283 283 LYS LYS G . n 
C 2 45  GLU 45  284 284 GLU GLU G . n 
C 2 46  LYS 46  285 285 LYS LYS G . n 
C 2 47  LEU 47  286 286 LEU LEU G . n 
C 2 48  GLN 48  287 287 GLN GLN G . n 
C 2 49  GLU 49  288 288 GLU GLU G . n 
C 2 50  GLU 50  289 289 GLU GLU G . n 
C 2 51  LEU 51  290 290 LEU LEU G . n 
C 2 52  ARG 52  291 291 ARG ARG G . n 
C 2 53  TRP 53  292 292 TRP TRP G . n 
C 2 54  ARG 54  293 293 ARG ARG G . n 
C 2 55  ARG 55  294 294 ARG ARG G . n 
C 2 56  THR 56  295 295 THR THR G . n 
C 2 57  PHE 57  296 296 PHE PHE G . n 
C 2 58  LEU 58  297 297 LEU LEU G . n 
C 2 59  HIS 59  298 298 HIS HIS G . n 
C 2 60  ALA 60  299 299 ALA ALA G . n 
C 2 61  VAL 61  300 300 VAL VAL G . n 
C 2 62  ASP 62  301 301 ASP ASP G . n 
C 2 63  VAL 63  302 302 VAL VAL G . n 
C 2 64  VAL 64  303 303 VAL VAL G . n 
C 2 65  LEU 65  304 304 LEU LEU G . n 
C 2 66  ASP 66  305 305 ASP ASP G . n 
C 2 67  PRO 67  306 306 PRO PRO G . n 
C 2 68  ASP 68  307 307 ASP ASP G . n 
C 2 69  THR 69  308 308 THR THR G . n 
C 2 70  ALA 70  309 309 ALA ALA G . n 
C 2 71  HIS 71  310 310 HIS HIS G . n 
C 2 72  PRO 72  311 311 PRO PRO G . n 
C 2 73  ASP 73  312 312 ASP ASP G . n 
C 2 74  LEU 74  313 313 LEU LEU G . n 
C 2 75  PHE 75  314 314 PHE PHE G . n 
C 2 76  LEU 76  315 315 LEU LEU G . n 
C 2 77  SER 77  316 316 SER SER G . n 
C 2 78  GLU 78  317 317 GLU GLU G . n 
C 2 79  ASP 79  318 318 ASP ASP G . n 
C 2 80  ARG 80  319 319 ARG ARG G . n 
C 2 81  ARG 81  320 320 ARG ARG G . n 
C 2 82  SER 82  321 321 SER SER G . n 
C 2 83  VAL 83  322 322 VAL VAL G . n 
C 2 84  ARG 84  323 323 ARG ARG G . n 
C 2 85  ARG 85  324 324 ARG ARG G . n 
C 2 86  CYS 86  325 325 CYS CYS G . n 
C 2 87  PRO 87  326 326 PRO PRO G . n 
C 2 88  PHE 88  327 327 PHE PHE G . n 
C 2 89  ARG 89  328 328 ARG ARG G . n 
C 2 90  HIS 90  329 329 HIS HIS G . n 
C 2 91  LEU 91  330 330 LEU LEU G . n 
C 2 92  GLY 92  331 331 GLY GLY G . n 
C 2 93  GLU 93  332 332 GLU GLU G . n 
C 2 94  SER 94  333 333 SER SER G . n 
C 2 95  VAL 95  334 334 VAL VAL G . n 
C 2 96  PRO 96  335 335 PRO PRO G . n 
C 2 97  ASP 97  336 336 ASP ASP G . n 
C 2 98  ASN 98  337 337 ASN ASN G . n 
C 2 99  PRO 99  338 338 PRO PRO G . n 
C 2 100 GLU 100 339 339 GLU GLU G . n 
C 2 101 ARG 101 340 340 ARG ARG G . n 
C 2 102 PHE 102 341 341 PHE PHE G . n 
C 2 103 ASP 103 342 342 ASP ASP G . n 
C 2 104 SER 104 343 343 SER SER G . n 
C 2 105 GLN 105 344 344 GLN GLN G . n 
C 2 106 PRO 106 345 345 PRO PRO G . n 
C 2 107 CYS 107 346 346 CYS CYS G . n 
C 2 108 VAL 108 347 347 VAL VAL G . n 
C 2 109 LEU 109 348 348 LEU LEU G . n 
C 2 110 GLY 110 349 349 GLY GLY G . n 
C 2 111 ARG 111 350 350 ARG ARG G . n 
C 2 112 GLU 112 351 351 GLU GLU G . n 
C 2 113 SER 113 352 352 SER SER G . n 
C 2 114 PHE 114 353 353 PHE PHE G . n 
C 2 115 ALA 115 354 354 ALA ALA G . n 
C 2 116 SER 116 355 355 SER SER G . n 
C 2 117 GLY 117 356 356 GLY GLY G . n 
C 2 118 LYS 118 357 357 LYS LYS G . n 
C 2 119 HIS 119 358 358 HIS HIS G . n 
C 2 120 TYR 120 359 359 TYR TYR G . n 
C 2 121 TRP 121 360 360 TRP TRP G . n 
C 2 122 GLU 122 361 361 GLU GLU G . n 
C 2 123 VAL 123 362 362 VAL VAL G . n 
C 2 124 GLU 124 363 363 GLU GLU G . n 
C 2 125 VAL 125 364 364 VAL VAL G . n 
C 2 126 GLU 126 365 365 GLU GLU G . n 
C 2 127 ASN 127 366 366 ASN ASN G . n 
C 2 128 VAL 128 367 367 VAL VAL G . n 
C 2 129 ILE 129 368 368 ILE ILE G . n 
C 2 130 GLU 130 369 369 GLU GLU G . n 
C 2 131 TRP 131 370 370 TRP TRP G . n 
C 2 132 THR 132 371 371 THR THR G . n 
C 2 133 VAL 133 372 372 VAL VAL G . n 
C 2 134 GLY 134 373 373 GLY GLY G . n 
C 2 135 VAL 135 374 374 VAL VAL G . n 
C 2 136 CYS 136 375 375 CYS CYS G . n 
C 2 137 ARG 137 376 376 ARG ARG G . n 
C 2 138 ASP 138 377 377 ASP ASP G . n 
C 2 139 SER 139 378 378 SER SER G . n 
C 2 140 VAL 140 379 379 VAL VAL G . n 
C 2 141 GLU 141 380 380 GLU GLU G . n 
C 2 142 ARG 142 381 381 ARG ARG G . n 
C 2 143 LYS 143 382 382 LYS LYS G . n 
C 2 144 GLY 144 383 383 GLY GLY G . n 
C 2 145 GLU 145 384 384 GLU GLU G . n 
C 2 146 VAL 146 385 385 VAL VAL G . n 
C 2 147 LEU 147 386 386 LEU LEU G . n 
C 2 148 LEU 148 387 387 LEU LEU G . n 
C 2 149 ILE 149 388 388 ILE ILE G . n 
C 2 150 PRO 150 389 389 PRO PRO G . n 
C 2 151 GLN 151 390 390 GLN GLN G . n 
C 2 152 ASN 152 391 391 ASN ASN G . n 
C 2 153 GLY 153 392 392 GLY GLY G . n 
C 2 154 PHE 154 393 393 PHE PHE G . n 
C 2 155 TRP 155 394 394 TRP TRP G . n 
C 2 156 THR 156 395 395 THR THR G . n 
C 2 157 LEU 157 396 396 LEU LEU G . n 
C 2 158 GLU 158 397 397 GLU GLU G . n 
C 2 159 MET 159 398 398 MET MET G . n 
C 2 160 HIS 160 399 399 HIS HIS G . n 
C 2 161 LYS 161 400 400 LYS LYS G . n 
C 2 162 GLY 162 401 401 GLY GLY G . n 
C 2 163 GLN 163 402 402 GLN GLN G . n 
C 2 164 TYR 164 403 403 TYR TYR G . n 
C 2 165 ARG 165 404 404 ARG ARG G . n 
C 2 166 ALA 166 405 405 ALA ALA G . n 
C 2 167 VAL 167 406 406 VAL VAL G . n 
C 2 168 SER 168 407 407 SER SER G . n 
C 2 169 SER 169 408 408 SER SER G . n 
C 2 170 PRO 170 409 409 PRO PRO G . n 
C 2 171 ASP 171 410 410 ASP ASP G . n 
C 2 172 ARG 172 411 411 ARG ARG G . n 
C 2 173 ILE 173 412 412 ILE ILE G . n 
C 2 174 LEU 174 413 413 LEU LEU G . n 
C 2 175 PRO 175 414 414 PRO PRO G . n 
C 2 176 LEU 176 415 415 LEU LEU G . n 
C 2 177 LYS 177 416 416 LYS LYS G . n 
C 2 178 GLU 178 417 417 GLU GLU G . n 
C 2 179 SER 179 418 418 SER SER G . n 
C 2 180 LEU 180 419 419 LEU LEU G . n 
C 2 181 CYS 181 420 420 CYS CYS G . n 
C 2 182 ARG 182 421 421 ARG ARG G . n 
C 2 183 VAL 183 422 422 VAL VAL G . n 
C 2 184 GLY 184 423 423 GLY GLY G . n 
C 2 185 VAL 185 424 424 VAL VAL G . n 
C 2 186 PHE 186 425 425 PHE PHE G . n 
C 2 187 LEU 187 426 426 LEU LEU G . n 
C 2 188 ASP 188 427 427 ASP ASP G . n 
C 2 189 TYR 189 428 428 TYR TYR G . n 
C 2 190 GLU 190 429 429 GLU GLU G . n 
C 2 191 ALA 191 430 430 ALA ALA G . n 
C 2 192 GLY 192 431 431 GLY GLY G . n 
C 2 193 ASP 193 432 432 ASP ASP G . n 
C 2 194 VAL 194 433 433 VAL VAL G . n 
C 2 195 SER 195 434 434 SER SER G . n 
C 2 196 PHE 196 435 435 PHE PHE G . n 
C 2 197 TYR 197 436 436 TYR TYR G . n 
C 2 198 ASN 198 437 437 ASN ASN G . n 
C 2 199 MET 199 438 438 MET MET G . n 
C 2 200 ARG 200 439 439 ARG ARG G . n 
C 2 201 ASP 201 440 440 ASP ASP G . n 
C 2 202 ARG 202 441 441 ARG ARG G . n 
C 2 203 SER 203 442 442 SER SER G . n 
C 2 204 HIS 204 443 443 HIS HIS G . n 
C 2 205 ILE 205 444 444 ILE ILE G . n 
C 2 206 TYR 206 445 445 TYR TYR G . n 
C 2 207 THR 207 446 446 THR THR G . n 
C 2 208 CYS 208 447 447 CYS CYS G . n 
C 2 209 PRO 209 448 448 PRO PRO G . n 
C 2 210 ARG 210 449 449 ARG ARG G . n 
C 2 211 SER 211 450 450 SER SER G . n 
C 2 212 ALA 212 451 451 ALA ALA G . n 
C 2 213 PHE 213 452 452 PHE PHE G . n 
C 2 214 SER 214 453 453 SER SER G . n 
C 2 215 VAL 215 454 454 VAL VAL G . n 
C 2 216 PRO 216 455 455 PRO PRO G . n 
C 2 217 VAL 217 456 456 VAL VAL G . n 
C 2 218 ARG 218 457 457 ARG ARG G . n 
C 2 219 PRO 219 458 458 PRO PRO G . n 
C 2 220 PHE 220 459 459 PHE PHE G . n 
C 2 221 PHE 221 460 460 PHE PHE G . n 
C 2 222 ARG 222 461 461 ARG ARG G . n 
C 2 223 LEU 223 462 462 LEU LEU G . n 
C 2 224 GLY 224 463 463 GLY GLY G . n 
C 2 225 CYS 225 464 464 CYS CYS G . n 
C 2 226 GLU 226 465 465 GLU GLU G . n 
C 2 227 ASP 227 466 466 ASP ASP G . n 
C 2 228 SER 228 467 467 SER SER G . n 
C 2 229 PRO 229 468 468 PRO PRO G . n 
C 2 230 ILE 230 469 469 ILE ILE G . n 
C 2 231 PHE 231 470 470 PHE PHE G . n 
C 2 232 ILE 232 471 471 ILE ILE G . n 
C 2 233 CYS 233 472 472 CYS CYS G . n 
C 2 234 PRO 234 473 473 PRO PRO G . n 
C 2 235 ALA 235 474 474 ALA ALA G . n 
C 2 236 LEU 236 475 475 LEU LEU G . n 
C 2 237 THR 237 476 476 THR THR G . n 
C 2 238 GLY 238 477 477 GLY GLY G . n 
C 2 239 ALA 239 478 478 ALA ALA G . n 
C 2 240 ASN 240 479 479 ASN ASN G . n 
C 2 241 GLY 241 480 480 GLY GLY G . n 
C 2 242 VAL 242 481 481 VAL VAL G . n 
C 2 243 THR 243 482 482 THR THR G . n 
C 2 244 VAL 244 483 483 VAL VAL G . n 
C 2 245 PRO 245 484 484 PRO PRO G . n 
C 2 246 GLU 246 485 485 GLU GLU G . n 
C 2 247 GLU 247 486 486 GLU GLU G . n 
C 2 248 GLY 248 487 487 GLY GLY G . n 
C 2 249 LEU 249 488 488 LEU LEU G . n 
C 2 250 THR 250 489 489 THR THR G . n 
C 2 251 LEU 251 490 490 LEU LEU G . n 
C 2 252 HIS 252 491 491 HIS HIS G . n 
C 2 253 ARG 253 492 492 ARG ARG G . n 
C 2 254 VAL 254 493 ?   ?   ?   G . n 
C 2 255 GLY 255 494 ?   ?   ?   G . n 
C 2 256 THR 256 495 ?   ?   ?   G . n 
C 2 257 HIS 257 496 ?   ?   ?   G . n 
C 2 258 GLN 258 497 ?   ?   ?   G . n 
C 2 259 SER 259 498 ?   ?   ?   G . n 
C 2 260 LEU 260 499 ?   ?   ?   G . n 
D 2 1   TRP 1   240 240 TRP TRP E . n 
D 2 2   ILE 2   241 241 ILE ILE E . n 
D 2 3   ASN 3   242 242 ASN ASN E . n 
D 2 4   LYS 4   243 243 LYS LYS E . n 
D 2 5   LEU 5   244 244 LEU LEU E . n 
D 2 6   GLN 6   245 245 GLN GLN E . n 
D 2 7   LYS 7   246 246 LYS LYS E . n 
D 2 8   GLU 8   247 247 GLU GLU E . n 
D 2 9   LYS 9   248 248 LYS LYS E . n 
D 2 10  LYS 10  249 249 LYS LYS E . n 
D 2 11  ILE 11  250 250 ILE ILE E . n 
D 2 12  LEU 12  251 251 LEU LEU E . n 
D 2 13  SER 13  252 252 SER SER E . n 
D 2 14  GLY 14  253 253 GLY GLY E . n 
D 2 15  GLU 15  254 254 GLU GLU E . n 
D 2 16  LYS 16  255 255 LYS LYS E . n 
D 2 17  GLU 17  256 256 GLU GLU E . n 
D 2 18  PHE 18  257 257 PHE PHE E . n 
D 2 19  GLU 19  258 258 GLU GLU E . n 
D 2 20  ARG 20  259 259 ARG ARG E . n 
D 2 21  GLU 21  260 260 GLU GLU E . n 
D 2 22  THR 22  261 261 THR THR E . n 
D 2 23  ARG 23  262 262 ARG ARG E . n 
D 2 24  GLU 24  263 263 GLU GLU E . n 
D 2 25  ILE 25  264 264 ILE ILE E . n 
D 2 26  ALA 26  265 265 ALA ALA E . n 
D 2 27  LEU 27  266 266 LEU LEU E . n 
D 2 28  LYS 28  267 267 LYS LYS E . n 
D 2 29  GLU 29  268 268 GLU GLU E . n 
D 2 30  LEU 30  269 269 LEU LEU E . n 
D 2 31  GLU 31  270 270 GLU GLU E . n 
D 2 32  LYS 32  271 271 LYS LYS E . n 
D 2 33  GLU 33  272 272 GLU GLU E . n 
D 2 34  ARG 34  273 273 ARG ARG E . n 
D 2 35  VAL 35  274 274 VAL VAL E . n 
D 2 36  GLN 36  275 275 GLN GLN E . n 
D 2 37  LYS 37  276 276 LYS LYS E . n 
D 2 38  GLU 38  277 277 GLU GLU E . n 
D 2 39  GLU 39  278 278 GLU GLU E . n 
D 2 40  GLU 40  279 279 GLU GLU E . n 
D 2 41  LEU 41  280 280 LEU LEU E . n 
D 2 42  GLN 42  281 281 GLN GLN E . n 
D 2 43  VAL 43  282 282 VAL VAL E . n 
D 2 44  LYS 44  283 283 LYS LYS E . n 
D 2 45  GLU 45  284 284 GLU GLU E . n 
D 2 46  LYS 46  285 285 LYS LYS E . n 
D 2 47  LEU 47  286 286 LEU LEU E . n 
D 2 48  GLN 48  287 287 GLN GLN E . n 
D 2 49  GLU 49  288 288 GLU GLU E . n 
D 2 50  GLU 50  289 289 GLU GLU E . n 
D 2 51  LEU 51  290 290 LEU LEU E . n 
D 2 52  ARG 52  291 291 ARG ARG E . n 
D 2 53  TRP 53  292 292 TRP TRP E . n 
D 2 54  ARG 54  293 293 ARG ARG E . n 
D 2 55  ARG 55  294 294 ARG ARG E . n 
D 2 56  THR 56  295 295 THR THR E . n 
D 2 57  PHE 57  296 296 PHE PHE E . n 
D 2 58  LEU 58  297 297 LEU LEU E . n 
D 2 59  HIS 59  298 298 HIS HIS E . n 
D 2 60  ALA 60  299 299 ALA ALA E . n 
D 2 61  VAL 61  300 300 VAL VAL E . n 
D 2 62  ASP 62  301 301 ASP ASP E . n 
D 2 63  VAL 63  302 302 VAL VAL E . n 
D 2 64  VAL 64  303 303 VAL VAL E . n 
D 2 65  LEU 65  304 304 LEU LEU E . n 
D 2 66  ASP 66  305 305 ASP ASP E . n 
D 2 67  PRO 67  306 306 PRO PRO E . n 
D 2 68  ASP 68  307 307 ASP ASP E . n 
D 2 69  THR 69  308 308 THR THR E . n 
D 2 70  ALA 70  309 309 ALA ALA E . n 
D 2 71  HIS 71  310 310 HIS HIS E . n 
D 2 72  PRO 72  311 311 PRO PRO E . n 
D 2 73  ASP 73  312 312 ASP ASP E . n 
D 2 74  LEU 74  313 313 LEU LEU E . n 
D 2 75  PHE 75  314 314 PHE PHE E . n 
D 2 76  LEU 76  315 315 LEU LEU E . n 
D 2 77  SER 77  316 316 SER SER E . n 
D 2 78  GLU 78  317 317 GLU GLU E . n 
D 2 79  ASP 79  318 318 ASP ASP E . n 
D 2 80  ARG 80  319 319 ARG ARG E . n 
D 2 81  ARG 81  320 320 ARG ARG E . n 
D 2 82  SER 82  321 321 SER SER E . n 
D 2 83  VAL 83  322 322 VAL VAL E . n 
D 2 84  ARG 84  323 323 ARG ARG E . n 
D 2 85  ARG 85  324 324 ARG ARG E . n 
D 2 86  CYS 86  325 325 CYS CYS E . n 
D 2 87  PRO 87  326 326 PRO PRO E . n 
D 2 88  PHE 88  327 327 PHE PHE E . n 
D 2 89  ARG 89  328 328 ARG ARG E . n 
D 2 90  HIS 90  329 329 HIS HIS E . n 
D 2 91  LEU 91  330 330 LEU LEU E . n 
D 2 92  GLY 92  331 331 GLY GLY E . n 
D 2 93  GLU 93  332 332 GLU GLU E . n 
D 2 94  SER 94  333 333 SER SER E . n 
D 2 95  VAL 95  334 334 VAL VAL E . n 
D 2 96  PRO 96  335 335 PRO PRO E . n 
D 2 97  ASP 97  336 336 ASP ASP E . n 
D 2 98  ASN 98  337 337 ASN ASN E . n 
D 2 99  PRO 99  338 338 PRO PRO E . n 
D 2 100 GLU 100 339 339 GLU GLU E . n 
D 2 101 ARG 101 340 340 ARG ARG E . n 
D 2 102 PHE 102 341 341 PHE PHE E . n 
D 2 103 ASP 103 342 342 ASP ASP E . n 
D 2 104 SER 104 343 343 SER SER E . n 
D 2 105 GLN 105 344 344 GLN GLN E . n 
D 2 106 PRO 106 345 345 PRO PRO E . n 
D 2 107 CYS 107 346 346 CYS CYS E . n 
D 2 108 VAL 108 347 347 VAL VAL E . n 
D 2 109 LEU 109 348 348 LEU LEU E . n 
D 2 110 GLY 110 349 349 GLY GLY E . n 
D 2 111 ARG 111 350 350 ARG ARG E . n 
D 2 112 GLU 112 351 351 GLU GLU E . n 
D 2 113 SER 113 352 352 SER SER E . n 
D 2 114 PHE 114 353 353 PHE PHE E . n 
D 2 115 ALA 115 354 354 ALA ALA E . n 
D 2 116 SER 116 355 355 SER SER E . n 
D 2 117 GLY 117 356 356 GLY GLY E . n 
D 2 118 LYS 118 357 357 LYS LYS E . n 
D 2 119 HIS 119 358 358 HIS HIS E . n 
D 2 120 TYR 120 359 359 TYR TYR E . n 
D 2 121 TRP 121 360 360 TRP TRP E . n 
D 2 122 GLU 122 361 361 GLU GLU E . n 
D 2 123 VAL 123 362 362 VAL VAL E . n 
D 2 124 GLU 124 363 363 GLU GLU E . n 
D 2 125 VAL 125 364 364 VAL VAL E . n 
D 2 126 GLU 126 365 365 GLU GLU E . n 
D 2 127 ASN 127 366 366 ASN ASN E . n 
D 2 128 VAL 128 367 367 VAL VAL E . n 
D 2 129 ILE 129 368 368 ILE ILE E . n 
D 2 130 GLU 130 369 369 GLU GLU E . n 
D 2 131 TRP 131 370 370 TRP TRP E . n 
D 2 132 THR 132 371 371 THR THR E . n 
D 2 133 VAL 133 372 372 VAL VAL E . n 
D 2 134 GLY 134 373 373 GLY GLY E . n 
D 2 135 VAL 135 374 374 VAL VAL E . n 
D 2 136 CYS 136 375 375 CYS CYS E . n 
D 2 137 ARG 137 376 376 ARG ARG E . n 
D 2 138 ASP 138 377 377 ASP ASP E . n 
D 2 139 SER 139 378 378 SER SER E . n 
D 2 140 VAL 140 379 379 VAL VAL E . n 
D 2 141 GLU 141 380 380 GLU GLU E . n 
D 2 142 ARG 142 381 381 ARG ARG E . n 
D 2 143 LYS 143 382 382 LYS LYS E . n 
D 2 144 GLY 144 383 383 GLY GLY E . n 
D 2 145 GLU 145 384 384 GLU GLU E . n 
D 2 146 VAL 146 385 385 VAL VAL E . n 
D 2 147 LEU 147 386 386 LEU LEU E . n 
D 2 148 LEU 148 387 387 LEU LEU E . n 
D 2 149 ILE 149 388 388 ILE ILE E . n 
D 2 150 PRO 150 389 389 PRO PRO E . n 
D 2 151 GLN 151 390 390 GLN GLN E . n 
D 2 152 ASN 152 391 391 ASN ASN E . n 
D 2 153 GLY 153 392 392 GLY GLY E . n 
D 2 154 PHE 154 393 393 PHE PHE E . n 
D 2 155 TRP 155 394 394 TRP TRP E . n 
D 2 156 THR 156 395 395 THR THR E . n 
D 2 157 LEU 157 396 396 LEU LEU E . n 
D 2 158 GLU 158 397 397 GLU GLU E . n 
D 2 159 MET 159 398 398 MET MET E . n 
D 2 160 HIS 160 399 399 HIS HIS E . n 
D 2 161 LYS 161 400 400 LYS LYS E . n 
D 2 162 GLY 162 401 401 GLY GLY E . n 
D 2 163 GLN 163 402 402 GLN GLN E . n 
D 2 164 TYR 164 403 403 TYR TYR E . n 
D 2 165 ARG 165 404 404 ARG ARG E . n 
D 2 166 ALA 166 405 405 ALA ALA E . n 
D 2 167 VAL 167 406 406 VAL VAL E . n 
D 2 168 SER 168 407 407 SER SER E . n 
D 2 169 SER 169 408 408 SER SER E . n 
D 2 170 PRO 170 409 409 PRO PRO E . n 
D 2 171 ASP 171 410 410 ASP ASP E . n 
D 2 172 ARG 172 411 411 ARG ARG E . n 
D 2 173 ILE 173 412 412 ILE ILE E . n 
D 2 174 LEU 174 413 413 LEU LEU E . n 
D 2 175 PRO 175 414 414 PRO PRO E . n 
D 2 176 LEU 176 415 415 LEU LEU E . n 
D 2 177 LYS 177 416 416 LYS LYS E . n 
D 2 178 GLU 178 417 417 GLU GLU E . n 
D 2 179 SER 179 418 418 SER SER E . n 
D 2 180 LEU 180 419 419 LEU LEU E . n 
D 2 181 CYS 181 420 420 CYS CYS E . n 
D 2 182 ARG 182 421 421 ARG ARG E . n 
D 2 183 VAL 183 422 422 VAL VAL E . n 
D 2 184 GLY 184 423 423 GLY GLY E . n 
D 2 185 VAL 185 424 424 VAL VAL E . n 
D 2 186 PHE 186 425 425 PHE PHE E . n 
D 2 187 LEU 187 426 426 LEU LEU E . n 
D 2 188 ASP 188 427 427 ASP ASP E . n 
D 2 189 TYR 189 428 428 TYR TYR E . n 
D 2 190 GLU 190 429 429 GLU GLU E . n 
D 2 191 ALA 191 430 430 ALA ALA E . n 
D 2 192 GLY 192 431 431 GLY GLY E . n 
D 2 193 ASP 193 432 432 ASP ASP E . n 
D 2 194 VAL 194 433 433 VAL VAL E . n 
D 2 195 SER 195 434 434 SER SER E . n 
D 2 196 PHE 196 435 435 PHE PHE E . n 
D 2 197 TYR 197 436 436 TYR TYR E . n 
D 2 198 ASN 198 437 437 ASN ASN E . n 
D 2 199 MET 199 438 438 MET MET E . n 
D 2 200 ARG 200 439 439 ARG ARG E . n 
D 2 201 ASP 201 440 440 ASP ASP E . n 
D 2 202 ARG 202 441 441 ARG ARG E . n 
D 2 203 SER 203 442 442 SER SER E . n 
D 2 204 HIS 204 443 443 HIS HIS E . n 
D 2 205 ILE 205 444 444 ILE ILE E . n 
D 2 206 TYR 206 445 445 TYR TYR E . n 
D 2 207 THR 207 446 446 THR THR E . n 
D 2 208 CYS 208 447 447 CYS CYS E . n 
D 2 209 PRO 209 448 448 PRO PRO E . n 
D 2 210 ARG 210 449 449 ARG ARG E . n 
D 2 211 SER 211 450 450 SER SER E . n 
D 2 212 ALA 212 451 451 ALA ALA E . n 
D 2 213 PHE 213 452 452 PHE PHE E . n 
D 2 214 SER 214 453 453 SER SER E . n 
D 2 215 VAL 215 454 454 VAL VAL E . n 
D 2 216 PRO 216 455 455 PRO PRO E . n 
D 2 217 VAL 217 456 456 VAL VAL E . n 
D 2 218 ARG 218 457 457 ARG ARG E . n 
D 2 219 PRO 219 458 458 PRO PRO E . n 
D 2 220 PHE 220 459 459 PHE PHE E . n 
D 2 221 PHE 221 460 460 PHE PHE E . n 
D 2 222 ARG 222 461 461 ARG ARG E . n 
D 2 223 LEU 223 462 462 LEU LEU E . n 
D 2 224 GLY 224 463 463 GLY GLY E . n 
D 2 225 CYS 225 464 464 CYS CYS E . n 
D 2 226 GLU 226 465 465 GLU GLU E . n 
D 2 227 ASP 227 466 466 ASP ASP E . n 
D 2 228 SER 228 467 467 SER SER E . n 
D 2 229 PRO 229 468 468 PRO PRO E . n 
D 2 230 ILE 230 469 469 ILE ILE E . n 
D 2 231 PHE 231 470 470 PHE PHE E . n 
D 2 232 ILE 232 471 471 ILE ILE E . n 
D 2 233 CYS 233 472 472 CYS CYS E . n 
D 2 234 PRO 234 473 473 PRO PRO E . n 
D 2 235 ALA 235 474 474 ALA ALA E . n 
D 2 236 LEU 236 475 475 LEU LEU E . n 
D 2 237 THR 237 476 476 THR THR E . n 
D 2 238 GLY 238 477 477 GLY GLY E . n 
D 2 239 ALA 239 478 478 ALA ALA E . n 
D 2 240 ASN 240 479 479 ASN ASN E . n 
D 2 241 GLY 241 480 480 GLY GLY E . n 
D 2 242 VAL 242 481 481 VAL VAL E . n 
D 2 243 THR 243 482 482 THR THR E . n 
D 2 244 VAL 244 483 483 VAL VAL E . n 
D 2 245 PRO 245 484 484 PRO PRO E . n 
D 2 246 GLU 246 485 485 GLU GLU E . n 
D 2 247 GLU 247 486 486 GLU GLU E . n 
D 2 248 GLY 248 487 487 GLY GLY E . n 
D 2 249 LEU 249 488 488 LEU LEU E . n 
D 2 250 THR 250 489 489 THR THR E . n 
D 2 251 LEU 251 490 490 LEU LEU E . n 
D 2 252 HIS 252 491 491 HIS HIS E . n 
D 2 253 ARG 253 492 492 ARG ARG E . n 
D 2 254 VAL 254 493 493 VAL VAL E . n 
D 2 255 GLY 255 494 ?   ?   ?   E . n 
D 2 256 THR 256 495 ?   ?   ?   E . n 
D 2 257 HIS 257 496 ?   ?   ?   E . n 
D 2 258 GLN 258 497 ?   ?   ?   E . n 
D 2 259 SER 259 498 ?   ?   ?   E . n 
D 2 260 LEU 260 499 ?   ?   ?   E . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        EIP 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   EIP 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
_pdbx_nonpoly_scheme.asym_id         E 
_pdbx_nonpoly_scheme.entity_id       3 
_pdbx_nonpoly_scheme.mon_id          EIP 
_pdbx_nonpoly_scheme.ndb_seq_num     1 
_pdbx_nonpoly_scheme.pdb_seq_num     501 
_pdbx_nonpoly_scheme.auth_seq_num    504 
_pdbx_nonpoly_scheme.pdb_mon_id      EIP 
_pdbx_nonpoly_scheme.auth_mon_id     H6P 
_pdbx_nonpoly_scheme.pdb_strand_id   D 
_pdbx_nonpoly_scheme.pdb_ins_code    . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 C THR 275 ? OG1 ? A THR 18  OG1 
2  1 Y 1 C THR 275 ? CG2 ? A THR 18  CG2 
3  1 Y 1 C SER 287 ? OG  ? A SER 30  OG  
4  1 Y 1 C TYR 300 ? CG  ? A TYR 43  CG  
5  1 Y 1 C TYR 300 ? CD1 ? A TYR 43  CD1 
6  1 Y 1 C TYR 300 ? CD2 ? A TYR 43  CD2 
7  1 Y 1 C TYR 300 ? CE1 ? A TYR 43  CE1 
8  1 Y 1 C TYR 300 ? CE2 ? A TYR 43  CE2 
9  1 Y 1 C TYR 300 ? CZ  ? A TYR 43  CZ  
10 1 Y 1 C TYR 300 ? OH  ? A TYR 43  OH  
11 1 Y 1 C GLU 302 ? CG  ? A GLU 45  CG  
12 1 Y 1 C GLU 302 ? CD  ? A GLU 45  CD  
13 1 Y 1 C GLU 302 ? OE1 ? A GLU 45  OE1 
14 1 Y 1 C GLU 302 ? OE2 ? A GLU 45  OE2 
15 1 Y 1 C LYS 309 ? CG  ? A LYS 52  CG  
16 1 Y 1 C LYS 309 ? CD  ? A LYS 52  CD  
17 1 Y 1 C LYS 309 ? CE  ? A LYS 52  CE  
18 1 Y 1 C LYS 309 ? NZ  ? A LYS 52  NZ  
19 1 Y 1 D GLU 302 ? CG  ? B GLU 45  CG  
20 1 Y 1 D GLU 302 ? CD  ? B GLU 45  CD  
21 1 Y 1 D GLU 302 ? OE1 ? B GLU 45  OE1 
22 1 Y 1 D GLU 302 ? OE2 ? B GLU 45  OE2 
23 1 Y 1 D LEU 472 ? CG  ? B LEU 215 CG  
24 1 Y 1 D LEU 472 ? CD1 ? B LEU 215 CD1 
25 1 Y 1 D LEU 472 ? CD2 ? B LEU 215 CD2 
26 1 Y 1 G TRP 240 ? CG  ? C TRP 1   CG  
27 1 Y 1 G TRP 240 ? CD1 ? C TRP 1   CD1 
28 1 Y 1 G TRP 240 ? CD2 ? C TRP 1   CD2 
29 1 Y 1 G TRP 240 ? NE1 ? C TRP 1   NE1 
30 1 Y 1 G TRP 240 ? CE2 ? C TRP 1   CE2 
31 1 Y 1 G TRP 240 ? CE3 ? C TRP 1   CE3 
32 1 Y 1 G TRP 240 ? CZ2 ? C TRP 1   CZ2 
33 1 Y 1 G TRP 240 ? CZ3 ? C TRP 1   CZ3 
34 1 Y 1 G TRP 240 ? CH2 ? C TRP 1   CH2 
35 1 Y 1 G LYS 248 ? CG  ? C LYS 9   CG  
36 1 Y 1 G LYS 248 ? CD  ? C LYS 9   CD  
37 1 Y 1 G LYS 248 ? CE  ? C LYS 9   CE  
38 1 Y 1 G LYS 248 ? NZ  ? C LYS 9   NZ  
39 1 Y 1 G LYS 249 ? CG  ? C LYS 10  CG  
40 1 Y 1 G LYS 249 ? CD  ? C LYS 10  CD  
41 1 Y 1 G LYS 249 ? CE  ? C LYS 10  CE  
42 1 Y 1 G LYS 249 ? NZ  ? C LYS 10  NZ  
43 1 Y 1 E TRP 240 ? CG  ? D TRP 1   CG  
44 1 Y 1 E TRP 240 ? CD1 ? D TRP 1   CD1 
45 1 Y 1 E TRP 240 ? CD2 ? D TRP 1   CD2 
46 1 Y 1 E TRP 240 ? NE1 ? D TRP 1   NE1 
47 1 Y 1 E TRP 240 ? CE2 ? D TRP 1   CE2 
48 1 Y 1 E TRP 240 ? CE3 ? D TRP 1   CE3 
49 1 Y 1 E TRP 240 ? CZ2 ? D TRP 1   CZ2 
50 1 Y 1 E TRP 240 ? CZ3 ? D TRP 1   CZ3 
51 1 Y 1 E TRP 240 ? CH2 ? D TRP 1   CH2 
52 1 Y 1 E LYS 248 ? CG  ? D LYS 9   CG  
53 1 Y 1 E LYS 248 ? CD  ? D LYS 9   CD  
54 1 Y 1 E LYS 248 ? CE  ? D LYS 9   CE  
55 1 Y 1 E LYS 248 ? NZ  ? D LYS 9   NZ  
56 1 Y 1 E LYS 249 ? CG  ? D LYS 10  CG  
57 1 Y 1 E LYS 249 ? CD  ? D LYS 10  CD  
58 1 Y 1 E LYS 249 ? CE  ? D LYS 10  CE  
59 1 Y 1 E LYS 249 ? NZ  ? D LYS 10  NZ  
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8ZAA 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8ZAA 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8ZAA 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               ? 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8ZAA 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            . 
_refine.ls_d_res_low                             ? 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.004 ? 7973  ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.768 ? 10801 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 5.479 ? 1055  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.045 ? 1150  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.007 ? 1405  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     8ZAA 
_struct.title                        'Cryo-EM structure of intracellular HBMBPP-BTN2A1-BTN3A1 complex' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8ZAA 
_struct_keywords.text            'complex, immune, IMMUNE SYSTEM' 
_struct_keywords.pdbx_keywords   'IMMUNE SYSTEM' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 2 ? 
D N N 2 ? 
E N N 3 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP BT3A1_HUMAN O00481 ? 1 
;EQELREMAWSTMKQEQSTRVKLLEELRWRSIQYASRGERHSAYNEWKKALFKPADVILDPKTANPILLVSEDQRSVQRAK
EPQDLPDNPERFNWHYCVLGCESFISGRHYWEVEVGDRKEWHIGVCSKNVQRKGWVKMTPENGFWTMGLTDGNKYRTLTE
PRTNLKLPKPPKKVGVFLDYETGDISFYNAVDGSHIHTFLDVSFSEALYPVFRILTLEPTALTICPA
;
287 
2 UNP BT2A1_HUMAN Q7KYR7 ? 2 
;WINKLQKEKKILSGEKEFERETREIALKELEKERVQKEEELQVKEKLQEELRWRRTFLHAVDVVLDPDTAHPDLFLSEDR
RSVRRCPFRHLGESVPDNPERFDSQPCVLGRESFASGKHYWEVEVENVIEWTVGVCRDSVERKGEVLLIPQNGFWTLEMH
KGQYRAVSSPDRILPLKESLCRVGVFLDYEAGDVSFYNMRDRSHIYTCPRSAFSVPVRPFFRLGCEDSPIFICPALTGAN
GVTVPEEGLTLHRVGTHQSL
;
268 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8ZAA C 1 ? 227 ? O00481 287 ? 513 ? 258 484 
2 1 8ZAA D 1 ? 227 ? O00481 287 ? 513 ? 258 484 
3 2 8ZAA G 1 ? 260 ? Q7KYR7 268 ? 527 ? 240 499 
4 2 8ZAA E 1 ? 260 ? Q7KYR7 268 ? 527 ? 240 499 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8ZAA THR C 170 ? UNP O00481 PRO 456 variant 427 1 
2 8ZAA THR D 170 ? UNP O00481 PRO 456 variant 427 2 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   tetrameric 
_pdbx_struct_assembly.oligomeric_count     4 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 GLN A 2   ? TYR A 33  ? GLN C 259 TYR C 290 1 ? 32 
HELX_P HELX_P2  AA2 SER A 41  ? LYS A 47  ? SER C 298 LYS C 304 1 ? 7  
HELX_P HELX_P3  AA3 ASP A 59  ? ALA A 63  ? ASP C 316 ALA C 320 5 ? 5  
HELX_P HELX_P4  AA4 THR A 139 ? ASN A 142 ? THR C 396 ASN C 399 5 ? 4  
HELX_P HELX_P5  AA5 SER B 10  ? SER B 35  ? SER D 267 SER D 292 1 ? 26 
HELX_P HELX_P6  AA6 ALA B 42  ? LYS B 47  ? ALA D 299 LYS D 304 1 ? 6  
HELX_P HELX_P7  AA7 ILE C 2   ? SER C 13  ? ILE G 241 SER G 252 1 ? 12 
HELX_P HELX_P8  AA8 GLU C 15  ? ARG C 54  ? GLU G 254 ARG G 293 1 ? 40 
HELX_P HELX_P9  AA9 GLU C 190 ? GLY C 192 ? GLU G 429 GLY G 431 5 ? 3  
HELX_P HELX_P10 AB1 ILE D 2   ? TRP D 53  ? ILE E 241 TRP E 292 1 ? 52 
HELX_P HELX_P11 AB2 ASP D 66  ? ALA D 70  ? ASP E 305 ALA E 309 5 ? 5  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 GLU 160 A . ? GLU 417 C PRO 161 A ? PRO 418 C 1 -9.51 
2 GLU 160 B . ? GLU 417 D PRO 161 B ? PRO 418 D 1 -0.91 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 7  ? 
AA2 ? 6  ? 
AA3 ? 5  ? 
AA4 ? 3  ? 
AA5 ? 2  ? 
AA6 ? 6  ? 
AA7 ? 10 ? 
AA8 ? 11 ? 
AA9 ? 5  ? 
AB1 ? 5  ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1  2  ? anti-parallel 
AA1 2  3  ? anti-parallel 
AA1 3  4  ? anti-parallel 
AA1 4  5  ? anti-parallel 
AA1 5  6  ? anti-parallel 
AA1 6  7  ? anti-parallel 
AA2 1  2  ? anti-parallel 
AA2 2  3  ? anti-parallel 
AA2 3  4  ? anti-parallel 
AA2 4  5  ? anti-parallel 
AA2 5  6  ? anti-parallel 
AA3 1  2  ? parallel      
AA3 2  3  ? anti-parallel 
AA3 3  4  ? anti-parallel 
AA3 4  5  ? anti-parallel 
AA4 1  2  ? parallel      
AA4 2  3  ? anti-parallel 
AA5 1  2  ? anti-parallel 
AA6 1  2  ? anti-parallel 
AA6 2  3  ? anti-parallel 
AA6 3  4  ? anti-parallel 
AA6 4  5  ? anti-parallel 
AA6 5  6  ? anti-parallel 
AA7 1  2  ? anti-parallel 
AA7 2  3  ? anti-parallel 
AA7 3  4  ? anti-parallel 
AA7 4  5  ? parallel      
AA7 5  6  ? anti-parallel 
AA7 6  7  ? parallel      
AA7 7  8  ? anti-parallel 
AA7 8  9  ? anti-parallel 
AA7 9  10 ? anti-parallel 
AA8 1  2  ? anti-parallel 
AA8 2  3  ? anti-parallel 
AA8 3  4  ? anti-parallel 
AA8 4  5  ? parallel      
AA8 5  6  ? anti-parallel 
AA8 6  7  ? parallel      
AA8 7  8  ? anti-parallel 
AA8 8  9  ? anti-parallel 
AA8 9  10 ? anti-parallel 
AA8 10 11 ? anti-parallel 
AA9 1  2  ? anti-parallel 
AA9 2  3  ? anti-parallel 
AA9 3  4  ? anti-parallel 
AA9 4  5  ? anti-parallel 
AB1 1  2  ? anti-parallel 
AB1 2  3  ? anti-parallel 
AB1 3  4  ? anti-parallel 
AB1 4  5  ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1  LEU A 67  ? VAL A 69  ? LEU C 324 VAL C 326 
AA1 2  SER A 75  ? ARG A 78  ? SER C 332 ARG C 335 
AA1 3  LEU A 222 ? CYS A 225 ? LEU C 479 CYS C 482 
AA1 4  ARG A 108 ? GLU A 114 ? ARG C 365 GLU C 371 
AA1 5  LYS A 173 ? ASP A 179 ? LYS C 430 ASP C 436 
AA1 6  ASP A 184 ? ASN A 189 ? ASP C 441 ASN C 446 
AA1 7  HIS A 195 ? PHE A 199 ? HIS C 452 PHE C 456 
AA2 1  CYS A 97  ? LEU A 99  ? CYS C 354 LEU C 356 
AA2 2  TYR A 209 ? ARG A 213 ? TYR C 466 ARG C 470 
AA2 3  TRP A 121 ? CYS A 126 ? TRP C 378 CYS C 383 
AA2 4  PHE A 144 ? THR A 150 ? PHE C 401 THR C 407 
AA2 5  LYS A 154 ? THR A 157 ? LYS C 411 THR C 414 
AA2 6  THR A 163 ? ASN A 164 ? THR C 420 ASN C 421 
AA3 1  LYS B 52  ? PRO B 53  ? LYS D 309 PRO D 310 
AA3 2  ARG B 108 ? GLU B 114 ? ARG D 365 GLU D 371 
AA3 3  LYS B 173 ? ASP B 179 ? LYS D 430 ASP D 436 
AA3 4  ASP B 184 ? ASN B 189 ? ASP D 441 ASN D 446 
AA3 5  HIS B 195 ? PHE B 199 ? HIS D 452 PHE D 456 
AA4 1  LYS B 52  ? PRO B 53  ? LYS D 309 PRO D 310 
AA4 2  ARG B 108 ? GLU B 114 ? ARG D 365 GLU D 371 
AA4 3  THR B 223 ? ILE B 224 ? THR D 480 ILE D 481 
AA5 1  LEU B 67  ? VAL B 69  ? LEU D 324 VAL D 326 
AA5 2  VAL B 76  ? ARG B 78  ? VAL D 333 ARG D 335 
AA6 1  CYS B 97  ? LEU B 99  ? CYS D 354 LEU D 356 
AA6 2  LEU B 208 ? ARG B 213 ? LEU D 465 ARG D 470 
AA6 3  TRP B 121 ? SER B 127 ? TRP D 378 SER D 384 
AA6 4  TRP B 145 ? THR B 150 ? TRP D 402 THR D 407 
AA6 5  LYS B 154 ? THR B 157 ? LYS D 411 THR D 414 
AA6 6  THR B 163 ? ASN B 164 ? THR D 420 ASN D 421 
AA7 1  LEU C 74  ? LEU C 76  ? LEU G 313 LEU G 315 
AA7 2  SER C 82  ? ARG C 85  ? SER G 321 ARG G 324 
AA7 3  ILE C 230 ? ILE C 232 ? ILE G 469 ILE G 471 
AA7 4  LYS C 118 ? GLU C 124 ? LYS G 357 GLU G 363 
AA7 5  LEU C 58  ? ALA C 60  ? LEU G 297 ALA G 299 
AA7 6  LEU D 58  ? ALA D 60  ? LEU E 297 ALA E 299 
AA7 7  LYS D 118 ? GLU D 124 ? LYS E 357 GLU E 363 
AA7 8  ARG D 182 ? ASP D 188 ? ARG E 421 ASP E 427 
AA7 9  ASP D 193 ? ASN D 198 ? ASP E 432 ASN E 437 
AA7 10 HIS D 204 ? CYS D 208 ? HIS E 443 CYS E 447 
AA8 1  LEU D 74  ? LEU D 76  ? LEU E 313 LEU E 315 
AA8 2  SER D 82  ? ARG D 85  ? SER E 321 ARG E 324 
AA8 3  ILE D 230 ? ILE D 232 ? ILE E 469 ILE E 471 
AA8 4  LYS D 118 ? GLU D 124 ? LYS E 357 GLU E 363 
AA8 5  LEU D 58  ? ALA D 60  ? LEU E 297 ALA E 299 
AA8 6  LEU C 58  ? ALA C 60  ? LEU G 297 ALA G 299 
AA8 7  LYS C 118 ? GLU C 124 ? LYS G 357 GLU G 363 
AA8 8  ARG C 182 ? ASP C 188 ? ARG G 421 ASP G 427 
AA8 9  ASP C 193 ? ASN C 198 ? ASP G 432 ASN G 437 
AA8 10 SER C 203 ? THR C 207 ? SER G 442 THR G 446 
AA8 11 LEU D 249 ? THR D 250 ? LEU E 488 THR E 489 
AA9 1  CYS C 107 ? LEU C 109 ? CYS G 346 LEU G 348 
AA9 2  VAL C 217 ? LEU C 223 ? VAL G 456 LEU G 462 
AA9 3  TRP C 131 ? ARG C 137 ? TRP G 370 ARG G 376 
AA9 4  PHE C 154 ? HIS C 160 ? PHE G 393 HIS G 399 
AA9 5  GLN C 163 ? ARG C 165 ? GLN G 402 ARG G 404 
AB1 1  CYS D 107 ? LEU D 109 ? CYS E 346 LEU E 348 
AB1 2  VAL D 217 ? LEU D 223 ? VAL E 456 LEU E 462 
AB1 3  TRP D 131 ? ARG D 137 ? TRP E 370 ARG E 376 
AB1 4  PHE D 154 ? HIS D 160 ? PHE E 393 HIS E 399 
AB1 5  GLN D 163 ? ARG D 165 ? GLN E 402 ARG E 404 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1  2  N LEU A 68  ? N LEU C 325 O GLN A 77  ? O GLN C 334 
AA1 2  3  N VAL A 76  ? N VAL C 333 O LEU A 222 ? O LEU C 479 
AA1 3  4  O THR A 223 ? O THR C 480 N GLU A 114 ? N GLU C 371 
AA1 4  5  N VAL A 113 ? N VAL C 370 O VAL A 174 ? O VAL C 431 
AA1 5  6  N GLY A 175 ? N GLY C 432 O TYR A 188 ? O TYR C 445 
AA1 6  7  N ILE A 185 ? N ILE C 442 O PHE A 199 ? O PHE C 456 
AA2 1  2  N VAL A 98  ? N VAL C 355 O PHE A 212 ? O PHE C 469 
AA2 2  3  O TYR A 209 ? O TYR C 466 N CYS A 126 ? N CYS C 383 
AA2 3  4  N ILE A 123 ? N ILE C 380 O MET A 147 ? O MET C 404 
AA2 4  5  N GLY A 148 ? N GLY C 405 O ARG A 156 ? O ARG C 413 
AA2 5  6  N THR A 157 ? N THR C 414 O THR A 163 ? O THR C 420 
AA3 1  2  N LYS B 52  ? N LYS D 309 O ARG B 108 ? O ARG D 365 
AA3 2  3  N VAL B 113 ? N VAL D 370 O VAL B 174 ? O VAL D 431 
AA3 3  4  N PHE B 177 ? N PHE D 434 O SER B 186 ? O SER D 443 
AA3 4  5  N PHE B 187 ? N PHE D 444 O HIS B 197 ? O HIS D 454 
AA4 1  2  N LYS B 52  ? N LYS D 309 O ARG B 108 ? O ARG D 365 
AA4 2  3  N GLU B 114 ? N GLU D 371 O THR B 223 ? O THR D 480 
AA5 1  2  N LEU B 68  ? N LEU D 325 O GLN B 77  ? O GLN D 334 
AA6 1  2  N VAL B 98  ? N VAL D 355 O PHE B 212 ? O PHE D 469 
AA6 2  3  O VAL B 211 ? O VAL D 468 N GLY B 124 ? N GLY D 381 
AA6 3  4  N ILE B 123 ? N ILE D 380 O MET B 147 ? O MET D 404 
AA6 4  5  N THR B 150 ? N THR D 407 O LYS B 154 ? O LYS D 411 
AA6 5  6  N THR B 157 ? N THR D 414 O THR B 163 ? O THR D 420 
AA7 1  2  N PHE C 75  ? N PHE G 314 O ARG C 84  ? O ARG G 323 
AA7 2  3  N VAL C 83  ? N VAL G 322 O ILE C 230 ? O ILE G 469 
AA7 3  4  O PHE C 231 ? O PHE G 470 N GLU C 124 ? N GLU G 363 
AA7 4  5  O LYS C 118 ? O LYS G 357 N HIS C 59  ? N HIS G 298 
AA7 5  6  N LEU C 58  ? N LEU G 297 O ALA D 60  ? O ALA E 299 
AA7 6  7  N HIS D 59  ? N HIS E 298 O LYS D 118 ? O LYS E 357 
AA7 7  8  N TRP D 121 ? N TRP E 360 O VAL D 185 ? O VAL E 424 
AA7 8  9  N PHE D 186 ? N PHE E 425 O SER D 195 ? O SER E 434 
AA7 9  10 N VAL D 194 ? N VAL E 433 O CYS D 208 ? O CYS E 447 
AA8 1  2  N PHE D 75  ? N PHE E 314 O ARG D 84  ? O ARG E 323 
AA8 2  3  N VAL D 83  ? N VAL E 322 O ILE D 230 ? O ILE E 469 
AA8 3  4  O PHE D 231 ? O PHE E 470 N GLU D 124 ? N GLU E 363 
AA8 4  5  O LYS D 118 ? O LYS E 357 N HIS D 59  ? N HIS E 298 
AA8 5  6  O ALA D 60  ? O ALA E 299 N LEU C 58  ? N LEU G 297 
AA8 6  7  N HIS C 59  ? N HIS G 298 O LYS C 118 ? O LYS G 357 
AA8 7  8  N HIS C 119 ? N HIS G 358 O LEU C 187 ? O LEU G 426 
AA8 8  9  N PHE C 186 ? N PHE G 425 O SER C 195 ? O SER G 434 
AA8 9  10 N ASN C 198 ? N ASN G 437 O SER C 203 ? O SER G 442 
AA8 10 11 N THR C 207 ? N THR G 446 O LEU D 249 ? O LEU E 488 
AA9 1  2  N VAL C 108 ? N VAL G 347 O PHE C 221 ? O PHE G 460 
AA9 2  3  O ARG C 218 ? O ARG G 457 N CYS C 136 ? N CYS G 375 
AA9 3  4  N VAL C 133 ? N VAL G 372 O LEU C 157 ? O LEU G 396 
AA9 4  5  N GLU C 158 ? N GLU G 397 O ARG C 165 ? O ARG G 404 
AB1 1  2  N VAL D 108 ? N VAL E 347 O PHE D 221 ? O PHE E 460 
AB1 2  3  O PHE D 220 ? O PHE E 459 N GLY D 134 ? N GLY E 373 
AB1 3  4  N VAL D 135 ? N VAL E 374 O TRP D 155 ? O TRP E 394 
AB1 4  5  N HIS D 160 ? N HIS E 399 O GLN D 163 ? O GLN E 402 
# 
_pdbx_entry_details.entry_id                   8ZAA 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   N 
# 
_pdbx_validate_rmsd_angle.id                         1 
_pdbx_validate_rmsd_angle.PDB_model_num              1 
_pdbx_validate_rmsd_angle.auth_atom_id_1             CA 
_pdbx_validate_rmsd_angle.auth_asym_id_1             C 
_pdbx_validate_rmsd_angle.auth_comp_id_1             PRO 
_pdbx_validate_rmsd_angle.auth_seq_id_1              310 
_pdbx_validate_rmsd_angle.PDB_ins_code_1             ? 
_pdbx_validate_rmsd_angle.label_alt_id_1             ? 
_pdbx_validate_rmsd_angle.auth_atom_id_2             N 
_pdbx_validate_rmsd_angle.auth_asym_id_2             C 
_pdbx_validate_rmsd_angle.auth_comp_id_2             PRO 
_pdbx_validate_rmsd_angle.auth_seq_id_2              310 
_pdbx_validate_rmsd_angle.PDB_ins_code_2             ? 
_pdbx_validate_rmsd_angle.label_alt_id_2             ? 
_pdbx_validate_rmsd_angle.auth_atom_id_3             CD 
_pdbx_validate_rmsd_angle.auth_asym_id_3             C 
_pdbx_validate_rmsd_angle.auth_comp_id_3             PRO 
_pdbx_validate_rmsd_angle.auth_seq_id_3              310 
_pdbx_validate_rmsd_angle.PDB_ins_code_3             ? 
_pdbx_validate_rmsd_angle.label_alt_id_3             ? 
_pdbx_validate_rmsd_angle.angle_value                95.33 
_pdbx_validate_rmsd_angle.angle_target_value         111.70 
_pdbx_validate_rmsd_angle.angle_deviation            -16.37 
_pdbx_validate_rmsd_angle.angle_standard_deviation   1.40 
_pdbx_validate_rmsd_angle.linker_flag                N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 TYR C 290 ? ? -68.67  6.25    
2  1 ARG C 296 ? ? -140.77 25.90   
3  1 LYS C 309 ? ? 51.06   72.75   
4  1 PRO C 310 ? ? -33.67  127.74  
5  1 TYR C 353 ? ? -92.19  49.95   
6  1 ASP C 374 ? ? -86.94  45.02   
7  1 GLU C 377 ? ? -162.14 115.64  
8  1 ASN C 386 ? ? -103.46 45.14   
9  1 ASP C 408 ? ? 39.63   50.81   
10 1 ARG D 293 ? ? -79.87  -168.50 
11 1 PRO D 317 ? ? -79.47  43.20   
12 1 ASP D 458 ? ? 72.75   -5.42   
13 1 LEU D 472 ? ? -92.88  47.49   
14 1 PRO D 483 ? ? -68.31  -179.61 
15 1 ARG G 293 ? ? -95.37  49.61   
16 1 HIS G 329 ? ? -97.12  31.31   
17 1 LYS G 400 ? ? 49.00   27.08   
18 1 ALA G 405 ? ? -78.66  -151.31 
19 1 VAL G 406 ? ? -53.69  9.23    
20 1 SER G 407 ? ? 83.72   20.32   
21 1 PRO G 409 ? ? -65.66  4.62    
22 1 ARG E 293 ? ? -77.51  -150.19 
23 1 ARG E 294 ? ? -58.66  64.01   
24 1 GLU E 339 ? ? -92.79  30.49   
25 1 ALA E 405 ? ? -78.09  -155.02 
26 1 VAL E 406 ? ? -58.62  8.61    
27 1 SER E 407 ? ? 85.81   11.87   
28 1 ILE E 444 ? ? -121.90 -59.41  
29 1 ALA E 478 ? ? -98.31  31.88   
# 
loop_
_pdbx_validate_peptide_omega.id 
_pdbx_validate_peptide_omega.PDB_model_num 
_pdbx_validate_peptide_omega.auth_comp_id_1 
_pdbx_validate_peptide_omega.auth_asym_id_1 
_pdbx_validate_peptide_omega.auth_seq_id_1 
_pdbx_validate_peptide_omega.PDB_ins_code_1 
_pdbx_validate_peptide_omega.label_alt_id_1 
_pdbx_validate_peptide_omega.auth_comp_id_2 
_pdbx_validate_peptide_omega.auth_asym_id_2 
_pdbx_validate_peptide_omega.auth_seq_id_2 
_pdbx_validate_peptide_omega.PDB_ins_code_2 
_pdbx_validate_peptide_omega.label_alt_id_2 
_pdbx_validate_peptide_omega.omega 
1 1 ARG E 293 ? ? ARG E 294 ? ? -138.38 
2 1 ARG E 294 ? ? THR E 295 ? ? 148.20  
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8ZAA 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    8ZAA 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.46 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               535747 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            8.0 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 BTN2A1-BTN3A1 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1,2 
# 
_em_imaging.entry_id                        8ZAA 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            50 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             1500 
_em_imaging.nominal_defocus_max             2500 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              8ZAA 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          NITROGEN 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                8ZAA 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 D GLU 258 ? B GLU 1   
2  1 Y 1 D GLN 259 ? B GLN 2   
3  1 Y 1 D GLU 260 ? B GLU 3   
4  1 Y 1 D LEU 261 ? B LEU 4   
5  1 Y 1 D ARG 262 ? B ARG 5   
6  1 Y 1 D GLU 263 ? B GLU 6   
7  1 Y 1 D MET 264 ? B MET 7   
8  1 Y 1 D ALA 265 ? B ALA 8   
9  1 Y 1 G VAL 493 ? C VAL 254 
10 1 Y 1 G GLY 494 ? C GLY 255 
11 1 Y 1 G THR 495 ? C THR 256 
12 1 Y 1 G HIS 496 ? C HIS 257 
13 1 Y 1 G GLN 497 ? C GLN 258 
14 1 Y 1 G SER 498 ? C SER 259 
15 1 Y 1 G LEU 499 ? C LEU 260 
16 1 Y 1 E GLY 494 ? D GLY 255 
17 1 Y 1 E THR 495 ? D THR 256 
18 1 Y 1 E HIS 496 ? D HIS 257 
19 1 Y 1 E GLN 497 ? D GLN 258 
20 1 Y 1 E SER 498 ? D SER 259 
21 1 Y 1 E LEU 499 ? D LEU 260 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
EIP O1   O N N 88  
EIP O2   O N N 89  
EIP O3   O N N 90  
EIP P4   P N N 91  
EIP O5   O N N 92  
EIP O6   O N N 93  
EIP O7   O N N 94  
EIP P8   P N S 95  
EIP O9   O N N 96  
EIP C10  C N N 97  
EIP C11  C N N 98  
EIP C12  C N S 99  
EIP C13  C N N 100 
EIP C14  C N N 101 
EIP O15  O N N 102 
EIP HO1  H N N 103 
EIP HO2  H N N 104 
EIP HO6  H N N 105 
EIP H101 H N N 106 
EIP H102 H N N 107 
EIP H111 H N N 108 
EIP H112 H N N 109 
EIP H12  H N N 110 
EIP H131 H N N 111 
EIP H132 H N N 112 
EIP H141 H N N 113 
EIP H142 H N N 114 
EIP H143 H N N 115 
EIP H15  H N N 116 
GLN N    N N N 117 
GLN CA   C N S 118 
GLN C    C N N 119 
GLN O    O N N 120 
GLN CB   C N N 121 
GLN CG   C N N 122 
GLN CD   C N N 123 
GLN OE1  O N N 124 
GLN NE2  N N N 125 
GLN OXT  O N N 126 
GLN H    H N N 127 
GLN H2   H N N 128 
GLN HA   H N N 129 
GLN HB2  H N N 130 
GLN HB3  H N N 131 
GLN HG2  H N N 132 
GLN HG3  H N N 133 
GLN HE21 H N N 134 
GLN HE22 H N N 135 
GLN HXT  H N N 136 
GLU N    N N N 137 
GLU CA   C N S 138 
GLU C    C N N 139 
GLU O    O N N 140 
GLU CB   C N N 141 
GLU CG   C N N 142 
GLU CD   C N N 143 
GLU OE1  O N N 144 
GLU OE2  O N N 145 
GLU OXT  O N N 146 
GLU H    H N N 147 
GLU H2   H N N 148 
GLU HA   H N N 149 
GLU HB2  H N N 150 
GLU HB3  H N N 151 
GLU HG2  H N N 152 
GLU HG3  H N N 153 
GLU HE2  H N N 154 
GLU HXT  H N N 155 
GLY N    N N N 156 
GLY CA   C N N 157 
GLY C    C N N 158 
GLY O    O N N 159 
GLY OXT  O N N 160 
GLY H    H N N 161 
GLY H2   H N N 162 
GLY HA2  H N N 163 
GLY HA3  H N N 164 
GLY HXT  H N N 165 
HIS N    N N N 166 
HIS CA   C N S 167 
HIS C    C N N 168 
HIS O    O N N 169 
HIS CB   C N N 170 
HIS CG   C Y N 171 
HIS ND1  N Y N 172 
HIS CD2  C Y N 173 
HIS CE1  C Y N 174 
HIS NE2  N Y N 175 
HIS OXT  O N N 176 
HIS H    H N N 177 
HIS H2   H N N 178 
HIS HA   H N N 179 
HIS HB2  H N N 180 
HIS HB3  H N N 181 
HIS HD1  H N N 182 
HIS HD2  H N N 183 
HIS HE1  H N N 184 
HIS HE2  H N N 185 
HIS HXT  H N N 186 
ILE N    N N N 187 
ILE CA   C N S 188 
ILE C    C N N 189 
ILE O    O N N 190 
ILE CB   C N S 191 
ILE CG1  C N N 192 
ILE CG2  C N N 193 
ILE CD1  C N N 194 
ILE OXT  O N N 195 
ILE H    H N N 196 
ILE H2   H N N 197 
ILE HA   H N N 198 
ILE HB   H N N 199 
ILE HG12 H N N 200 
ILE HG13 H N N 201 
ILE HG21 H N N 202 
ILE HG22 H N N 203 
ILE HG23 H N N 204 
ILE HD11 H N N 205 
ILE HD12 H N N 206 
ILE HD13 H N N 207 
ILE HXT  H N N 208 
LEU N    N N N 209 
LEU CA   C N S 210 
LEU C    C N N 211 
LEU O    O N N 212 
LEU CB   C N N 213 
LEU CG   C N N 214 
LEU CD1  C N N 215 
LEU CD2  C N N 216 
LEU OXT  O N N 217 
LEU H    H N N 218 
LEU H2   H N N 219 
LEU HA   H N N 220 
LEU HB2  H N N 221 
LEU HB3  H N N 222 
LEU HG   H N N 223 
LEU HD11 H N N 224 
LEU HD12 H N N 225 
LEU HD13 H N N 226 
LEU HD21 H N N 227 
LEU HD22 H N N 228 
LEU HD23 H N N 229 
LEU HXT  H N N 230 
LYS N    N N N 231 
LYS CA   C N S 232 
LYS C    C N N 233 
LYS O    O N N 234 
LYS CB   C N N 235 
LYS CG   C N N 236 
LYS CD   C N N 237 
LYS CE   C N N 238 
LYS NZ   N N N 239 
LYS OXT  O N N 240 
LYS H    H N N 241 
LYS H2   H N N 242 
LYS HA   H N N 243 
LYS HB2  H N N 244 
LYS HB3  H N N 245 
LYS HG2  H N N 246 
LYS HG3  H N N 247 
LYS HD2  H N N 248 
LYS HD3  H N N 249 
LYS HE2  H N N 250 
LYS HE3  H N N 251 
LYS HZ1  H N N 252 
LYS HZ2  H N N 253 
LYS HZ3  H N N 254 
LYS HXT  H N N 255 
MET N    N N N 256 
MET CA   C N S 257 
MET C    C N N 258 
MET O    O N N 259 
MET CB   C N N 260 
MET CG   C N N 261 
MET SD   S N N 262 
MET CE   C N N 263 
MET OXT  O N N 264 
MET H    H N N 265 
MET H2   H N N 266 
MET HA   H N N 267 
MET HB2  H N N 268 
MET HB3  H N N 269 
MET HG2  H N N 270 
MET HG3  H N N 271 
MET HE1  H N N 272 
MET HE2  H N N 273 
MET HE3  H N N 274 
MET HXT  H N N 275 
PHE N    N N N 276 
PHE CA   C N S 277 
PHE C    C N N 278 
PHE O    O N N 279 
PHE CB   C N N 280 
PHE CG   C Y N 281 
PHE CD1  C Y N 282 
PHE CD2  C Y N 283 
PHE CE1  C Y N 284 
PHE CE2  C Y N 285 
PHE CZ   C Y N 286 
PHE OXT  O N N 287 
PHE H    H N N 288 
PHE H2   H N N 289 
PHE HA   H N N 290 
PHE HB2  H N N 291 
PHE HB3  H N N 292 
PHE HD1  H N N 293 
PHE HD2  H N N 294 
PHE HE1  H N N 295 
PHE HE2  H N N 296 
PHE HZ   H N N 297 
PHE HXT  H N N 298 
PRO N    N N N 299 
PRO CA   C N S 300 
PRO C    C N N 301 
PRO O    O N N 302 
PRO CB   C N N 303 
PRO CG   C N N 304 
PRO CD   C N N 305 
PRO OXT  O N N 306 
PRO H    H N N 307 
PRO HA   H N N 308 
PRO HB2  H N N 309 
PRO HB3  H N N 310 
PRO HG2  H N N 311 
PRO HG3  H N N 312 
PRO HD2  H N N 313 
PRO HD3  H N N 314 
PRO HXT  H N N 315 
SER N    N N N 316 
SER CA   C N S 317 
SER C    C N N 318 
SER O    O N N 319 
SER CB   C N N 320 
SER OG   O N N 321 
SER OXT  O N N 322 
SER H    H N N 323 
SER H2   H N N 324 
SER HA   H N N 325 
SER HB2  H N N 326 
SER HB3  H N N 327 
SER HG   H N N 328 
SER HXT  H N N 329 
THR N    N N N 330 
THR CA   C N S 331 
THR C    C N N 332 
THR O    O N N 333 
THR CB   C N R 334 
THR OG1  O N N 335 
THR CG2  C N N 336 
THR OXT  O N N 337 
THR H    H N N 338 
THR H2   H N N 339 
THR HA   H N N 340 
THR HB   H N N 341 
THR HG1  H N N 342 
THR HG21 H N N 343 
THR HG22 H N N 344 
THR HG23 H N N 345 
THR HXT  H N N 346 
TRP N    N N N 347 
TRP CA   C N S 348 
TRP C    C N N 349 
TRP O    O N N 350 
TRP CB   C N N 351 
TRP CG   C Y N 352 
TRP CD1  C Y N 353 
TRP CD2  C Y N 354 
TRP NE1  N Y N 355 
TRP CE2  C Y N 356 
TRP CE3  C Y N 357 
TRP CZ2  C Y N 358 
TRP CZ3  C Y N 359 
TRP CH2  C Y N 360 
TRP OXT  O N N 361 
TRP H    H N N 362 
TRP H2   H N N 363 
TRP HA   H N N 364 
TRP HB2  H N N 365 
TRP HB3  H N N 366 
TRP HD1  H N N 367 
TRP HE1  H N N 368 
TRP HE3  H N N 369 
TRP HZ2  H N N 370 
TRP HZ3  H N N 371 
TRP HH2  H N N 372 
TRP HXT  H N N 373 
TYR N    N N N 374 
TYR CA   C N S 375 
TYR C    C N N 376 
TYR O    O N N 377 
TYR CB   C N N 378 
TYR CG   C Y N 379 
TYR CD1  C Y N 380 
TYR CD2  C Y N 381 
TYR CE1  C Y N 382 
TYR CE2  C Y N 383 
TYR CZ   C Y N 384 
TYR OH   O N N 385 
TYR OXT  O N N 386 
TYR H    H N N 387 
TYR H2   H N N 388 
TYR HA   H N N 389 
TYR HB2  H N N 390 
TYR HB3  H N N 391 
TYR HD1  H N N 392 
TYR HD2  H N N 393 
TYR HE1  H N N 394 
TYR HE2  H N N 395 
TYR HH   H N N 396 
TYR HXT  H N N 397 
VAL N    N N N 398 
VAL CA   C N S 399 
VAL C    C N N 400 
VAL O    O N N 401 
VAL CB   C N N 402 
VAL CG1  C N N 403 
VAL CG2  C N N 404 
VAL OXT  O N N 405 
VAL H    H N N 406 
VAL H2   H N N 407 
VAL HA   H N N 408 
VAL HB   H N N 409 
VAL HG11 H N N 410 
VAL HG12 H N N 411 
VAL HG13 H N N 412 
VAL HG21 H N N 413 
VAL HG22 H N N 414 
VAL HG23 H N N 415 
VAL HXT  H N N 416 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
EIP O1  P4   sing N N 83  
EIP O1  HO1  sing N N 84  
EIP O2  P4   sing N N 85  
EIP O2  HO2  sing N N 86  
EIP O3  P4   doub N N 87  
EIP P4  O5   sing N N 88  
EIP O5  P8   sing N N 89  
EIP O6  P8   sing N N 90  
EIP O6  HO6  sing N N 91  
EIP O7  P8   doub N N 92  
EIP P8  O9   sing N N 93  
EIP O9  C10  sing N N 94  
EIP C10 C11  sing N N 95  
EIP C10 H101 sing N N 96  
EIP C10 H102 sing N N 97  
EIP C11 C12  sing N N 98  
EIP C11 H111 sing N N 99  
EIP C11 H112 sing N N 100 
EIP C12 C13  sing N N 101 
EIP C12 C14  sing N N 102 
EIP C12 H12  sing N N 103 
EIP C13 O15  sing N N 104 
EIP C13 H131 sing N N 105 
EIP C13 H132 sing N N 106 
EIP C14 H141 sing N N 107 
EIP C14 H142 sing N N 108 
EIP C14 H143 sing N N 109 
EIP O15 H15  sing N N 110 
GLN N   CA   sing N N 111 
GLN N   H    sing N N 112 
GLN N   H2   sing N N 113 
GLN CA  C    sing N N 114 
GLN CA  CB   sing N N 115 
GLN CA  HA   sing N N 116 
GLN C   O    doub N N 117 
GLN C   OXT  sing N N 118 
GLN CB  CG   sing N N 119 
GLN CB  HB2  sing N N 120 
GLN CB  HB3  sing N N 121 
GLN CG  CD   sing N N 122 
GLN CG  HG2  sing N N 123 
GLN CG  HG3  sing N N 124 
GLN CD  OE1  doub N N 125 
GLN CD  NE2  sing N N 126 
GLN NE2 HE21 sing N N 127 
GLN NE2 HE22 sing N N 128 
GLN OXT HXT  sing N N 129 
GLU N   CA   sing N N 130 
GLU N   H    sing N N 131 
GLU N   H2   sing N N 132 
GLU CA  C    sing N N 133 
GLU CA  CB   sing N N 134 
GLU CA  HA   sing N N 135 
GLU C   O    doub N N 136 
GLU C   OXT  sing N N 137 
GLU CB  CG   sing N N 138 
GLU CB  HB2  sing N N 139 
GLU CB  HB3  sing N N 140 
GLU CG  CD   sing N N 141 
GLU CG  HG2  sing N N 142 
GLU CG  HG3  sing N N 143 
GLU CD  OE1  doub N N 144 
GLU CD  OE2  sing N N 145 
GLU OE2 HE2  sing N N 146 
GLU OXT HXT  sing N N 147 
GLY N   CA   sing N N 148 
GLY N   H    sing N N 149 
GLY N   H2   sing N N 150 
GLY CA  C    sing N N 151 
GLY CA  HA2  sing N N 152 
GLY CA  HA3  sing N N 153 
GLY C   O    doub N N 154 
GLY C   OXT  sing N N 155 
GLY OXT HXT  sing N N 156 
HIS N   CA   sing N N 157 
HIS N   H    sing N N 158 
HIS N   H2   sing N N 159 
HIS CA  C    sing N N 160 
HIS CA  CB   sing N N 161 
HIS CA  HA   sing N N 162 
HIS C   O    doub N N 163 
HIS C   OXT  sing N N 164 
HIS CB  CG   sing N N 165 
HIS CB  HB2  sing N N 166 
HIS CB  HB3  sing N N 167 
HIS CG  ND1  sing Y N 168 
HIS CG  CD2  doub Y N 169 
HIS ND1 CE1  doub Y N 170 
HIS ND1 HD1  sing N N 171 
HIS CD2 NE2  sing Y N 172 
HIS CD2 HD2  sing N N 173 
HIS CE1 NE2  sing Y N 174 
HIS CE1 HE1  sing N N 175 
HIS NE2 HE2  sing N N 176 
HIS OXT HXT  sing N N 177 
ILE N   CA   sing N N 178 
ILE N   H    sing N N 179 
ILE N   H2   sing N N 180 
ILE CA  C    sing N N 181 
ILE CA  CB   sing N N 182 
ILE CA  HA   sing N N 183 
ILE C   O    doub N N 184 
ILE C   OXT  sing N N 185 
ILE CB  CG1  sing N N 186 
ILE CB  CG2  sing N N 187 
ILE CB  HB   sing N N 188 
ILE CG1 CD1  sing N N 189 
ILE CG1 HG12 sing N N 190 
ILE CG1 HG13 sing N N 191 
ILE CG2 HG21 sing N N 192 
ILE CG2 HG22 sing N N 193 
ILE CG2 HG23 sing N N 194 
ILE CD1 HD11 sing N N 195 
ILE CD1 HD12 sing N N 196 
ILE CD1 HD13 sing N N 197 
ILE OXT HXT  sing N N 198 
LEU N   CA   sing N N 199 
LEU N   H    sing N N 200 
LEU N   H2   sing N N 201 
LEU CA  C    sing N N 202 
LEU CA  CB   sing N N 203 
LEU CA  HA   sing N N 204 
LEU C   O    doub N N 205 
LEU C   OXT  sing N N 206 
LEU CB  CG   sing N N 207 
LEU CB  HB2  sing N N 208 
LEU CB  HB3  sing N N 209 
LEU CG  CD1  sing N N 210 
LEU CG  CD2  sing N N 211 
LEU CG  HG   sing N N 212 
LEU CD1 HD11 sing N N 213 
LEU CD1 HD12 sing N N 214 
LEU CD1 HD13 sing N N 215 
LEU CD2 HD21 sing N N 216 
LEU CD2 HD22 sing N N 217 
LEU CD2 HD23 sing N N 218 
LEU OXT HXT  sing N N 219 
LYS N   CA   sing N N 220 
LYS N   H    sing N N 221 
LYS N   H2   sing N N 222 
LYS CA  C    sing N N 223 
LYS CA  CB   sing N N 224 
LYS CA  HA   sing N N 225 
LYS C   O    doub N N 226 
LYS C   OXT  sing N N 227 
LYS CB  CG   sing N N 228 
LYS CB  HB2  sing N N 229 
LYS CB  HB3  sing N N 230 
LYS CG  CD   sing N N 231 
LYS CG  HG2  sing N N 232 
LYS CG  HG3  sing N N 233 
LYS CD  CE   sing N N 234 
LYS CD  HD2  sing N N 235 
LYS CD  HD3  sing N N 236 
LYS CE  NZ   sing N N 237 
LYS CE  HE2  sing N N 238 
LYS CE  HE3  sing N N 239 
LYS NZ  HZ1  sing N N 240 
LYS NZ  HZ2  sing N N 241 
LYS NZ  HZ3  sing N N 242 
LYS OXT HXT  sing N N 243 
MET N   CA   sing N N 244 
MET N   H    sing N N 245 
MET N   H2   sing N N 246 
MET CA  C    sing N N 247 
MET CA  CB   sing N N 248 
MET CA  HA   sing N N 249 
MET C   O    doub N N 250 
MET C   OXT  sing N N 251 
MET CB  CG   sing N N 252 
MET CB  HB2  sing N N 253 
MET CB  HB3  sing N N 254 
MET CG  SD   sing N N 255 
MET CG  HG2  sing N N 256 
MET CG  HG3  sing N N 257 
MET SD  CE   sing N N 258 
MET CE  HE1  sing N N 259 
MET CE  HE2  sing N N 260 
MET CE  HE3  sing N N 261 
MET OXT HXT  sing N N 262 
PHE N   CA   sing N N 263 
PHE N   H    sing N N 264 
PHE N   H2   sing N N 265 
PHE CA  C    sing N N 266 
PHE CA  CB   sing N N 267 
PHE CA  HA   sing N N 268 
PHE C   O    doub N N 269 
PHE C   OXT  sing N N 270 
PHE CB  CG   sing N N 271 
PHE CB  HB2  sing N N 272 
PHE CB  HB3  sing N N 273 
PHE CG  CD1  doub Y N 274 
PHE CG  CD2  sing Y N 275 
PHE CD1 CE1  sing Y N 276 
PHE CD1 HD1  sing N N 277 
PHE CD2 CE2  doub Y N 278 
PHE CD2 HD2  sing N N 279 
PHE CE1 CZ   doub Y N 280 
PHE CE1 HE1  sing N N 281 
PHE CE2 CZ   sing Y N 282 
PHE CE2 HE2  sing N N 283 
PHE CZ  HZ   sing N N 284 
PHE OXT HXT  sing N N 285 
PRO N   CA   sing N N 286 
PRO N   CD   sing N N 287 
PRO N   H    sing N N 288 
PRO CA  C    sing N N 289 
PRO CA  CB   sing N N 290 
PRO CA  HA   sing N N 291 
PRO C   O    doub N N 292 
PRO C   OXT  sing N N 293 
PRO CB  CG   sing N N 294 
PRO CB  HB2  sing N N 295 
PRO CB  HB3  sing N N 296 
PRO CG  CD   sing N N 297 
PRO CG  HG2  sing N N 298 
PRO CG  HG3  sing N N 299 
PRO CD  HD2  sing N N 300 
PRO CD  HD3  sing N N 301 
PRO OXT HXT  sing N N 302 
SER N   CA   sing N N 303 
SER N   H    sing N N 304 
SER N   H2   sing N N 305 
SER CA  C    sing N N 306 
SER CA  CB   sing N N 307 
SER CA  HA   sing N N 308 
SER C   O    doub N N 309 
SER C   OXT  sing N N 310 
SER CB  OG   sing N N 311 
SER CB  HB2  sing N N 312 
SER CB  HB3  sing N N 313 
SER OG  HG   sing N N 314 
SER OXT HXT  sing N N 315 
THR N   CA   sing N N 316 
THR N   H    sing N N 317 
THR N   H2   sing N N 318 
THR CA  C    sing N N 319 
THR CA  CB   sing N N 320 
THR CA  HA   sing N N 321 
THR C   O    doub N N 322 
THR C   OXT  sing N N 323 
THR CB  OG1  sing N N 324 
THR CB  CG2  sing N N 325 
THR CB  HB   sing N N 326 
THR OG1 HG1  sing N N 327 
THR CG2 HG21 sing N N 328 
THR CG2 HG22 sing N N 329 
THR CG2 HG23 sing N N 330 
THR OXT HXT  sing N N 331 
TRP N   CA   sing N N 332 
TRP N   H    sing N N 333 
TRP N   H2   sing N N 334 
TRP CA  C    sing N N 335 
TRP CA  CB   sing N N 336 
TRP CA  HA   sing N N 337 
TRP C   O    doub N N 338 
TRP C   OXT  sing N N 339 
TRP CB  CG   sing N N 340 
TRP CB  HB2  sing N N 341 
TRP CB  HB3  sing N N 342 
TRP CG  CD1  doub Y N 343 
TRP CG  CD2  sing Y N 344 
TRP CD1 NE1  sing Y N 345 
TRP CD1 HD1  sing N N 346 
TRP CD2 CE2  doub Y N 347 
TRP CD2 CE3  sing Y N 348 
TRP NE1 CE2  sing Y N 349 
TRP NE1 HE1  sing N N 350 
TRP CE2 CZ2  sing Y N 351 
TRP CE3 CZ3  doub Y N 352 
TRP CE3 HE3  sing N N 353 
TRP CZ2 CH2  doub Y N 354 
TRP CZ2 HZ2  sing N N 355 
TRP CZ3 CH2  sing Y N 356 
TRP CZ3 HZ3  sing N N 357 
TRP CH2 HH2  sing N N 358 
TRP OXT HXT  sing N N 359 
TYR N   CA   sing N N 360 
TYR N   H    sing N N 361 
TYR N   H2   sing N N 362 
TYR CA  C    sing N N 363 
TYR CA  CB   sing N N 364 
TYR CA  HA   sing N N 365 
TYR C   O    doub N N 366 
TYR C   OXT  sing N N 367 
TYR CB  CG   sing N N 368 
TYR CB  HB2  sing N N 369 
TYR CB  HB3  sing N N 370 
TYR CG  CD1  doub Y N 371 
TYR CG  CD2  sing Y N 372 
TYR CD1 CE1  sing Y N 373 
TYR CD1 HD1  sing N N 374 
TYR CD2 CE2  doub Y N 375 
TYR CD2 HD2  sing N N 376 
TYR CE1 CZ   doub Y N 377 
TYR CE1 HE1  sing N N 378 
TYR CE2 CZ   sing Y N 379 
TYR CE2 HE2  sing N N 380 
TYR CZ  OH   sing N N 381 
TYR OH  HH   sing N N 382 
TYR OXT HXT  sing N N 383 
VAL N   CA   sing N N 384 
VAL N   H    sing N N 385 
VAL N   H2   sing N N 386 
VAL CA  C    sing N N 387 
VAL CA  CB   sing N N 388 
VAL CA  HA   sing N N 389 
VAL C   O    doub N N 390 
VAL C   OXT  sing N N 391 
VAL CB  CG1  sing N N 392 
VAL CB  CG2  sing N N 393 
VAL CB  HB   sing N N 394 
VAL CG1 HG11 sing N N 395 
VAL CG1 HG12 sing N N 396 
VAL CG1 HG13 sing N N 397 
VAL CG2 HG21 sing N N 398 
VAL CG2 HG22 sing N N 399 
VAL CG2 HG23 sing N N 400 
VAL OXT HXT  sing N N 401 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-04-24 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           8ZAA 
_em_admin.last_update        2025-04-30 
_em_admin.map_release_date   2025-04-30 
_em_admin.title              'Cryo-EM structure of intracellular HBMBPP-BTN2A1-BTN3A1 complex' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          9606 
_em_entity_assembly_recombinant.organism             'Homo sapiens' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         50 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? ?      ?          
'MODEL REFINEMENT'         ? 2  ? ? ? PHENIX 1.20_4459: 
'IMAGE ACQUISITION'        ? 3  1 1 1 ?      ?          
MASKING                    ? 4  1 1 1 ?      ?          
'CTF CORRECTION'           ? 5  1 ? ? ?      ?          
'LAYERLINE INDEXING'       ? 6  1 1 1 ?      ?          
'DIFFRACTION INDEXING'     ? 7  1 1 1 ?      ?          
'MODEL FITTING'            ? 8  1 1 1 ?      ?          
OTHER                      ? 9  1 1 1 ?      ?          
'INITIAL EULER ASSIGNMENT' ? 10 1 ? ? ?      ?          
'FINAL EULER ASSIGNMENT'   ? 11 1 ? ? ?      ?          
CLASSIFICATION             ? 12 1 ? ? ?      ?          
RECONSTRUCTION             ? 13 1 ? ? ?      ?          
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'National Natural Science Foundation of China (NSFC)' 
_pdbx_audit_support.country                China 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    8ZAA 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
P 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . GLU A 1 1   ? 218.692 258.744 214.539 1.00 324.31 ? 258 GLU C N   1 
ATOM   2    C CA  . GLU A 1 1   ? 218.844 257.778 215.621 1.00 324.33 ? 258 GLU C CA  1 
ATOM   3    C C   . GLU A 1 1   ? 218.638 258.437 216.980 1.00 324.44 ? 258 GLU C C   1 
ATOM   4    O O   . GLU A 1 1   ? 219.519 259.135 217.482 1.00 324.51 ? 258 GLU C O   1 
ATOM   5    C CB  . GLU A 1 1   ? 220.224 257.120 215.562 1.00 324.44 ? 258 GLU C CB  1 
ATOM   6    C CG  . GLU A 1 1   ? 220.383 255.933 216.497 1.00 324.47 ? 258 GLU C CG  1 
ATOM   7    C CD  . GLU A 1 1   ? 221.835 255.586 216.754 1.00 324.53 ? 258 GLU C CD  1 
ATOM   8    O OE1 . GLU A 1 1   ? 222.718 256.353 216.316 1.00 324.74 ? 258 GLU C OE1 1 
ATOM   9    O OE2 . GLU A 1 1   ? 222.095 254.545 217.393 1.00 324.52 ? 258 GLU C OE2 1 
ATOM   10   N N   . GLN A 1 2   ? 217.468 258.210 217.571 1.00 318.98 ? 259 GLN C N   1 
ATOM   11   C CA  . GLN A 1 2   ? 217.137 258.764 218.876 1.00 318.93 ? 259 GLN C CA  1 
ATOM   12   C C   . GLN A 1 2   ? 217.508 257.837 220.026 1.00 319.07 ? 259 GLN C C   1 
ATOM   13   O O   . GLN A 1 2   ? 217.289 258.198 221.186 1.00 319.15 ? 259 GLN C O   1 
ATOM   14   C CB  . GLN A 1 2   ? 215.642 259.094 218.944 1.00 318.78 ? 259 GLN C CB  1 
ATOM   15   C CG  . GLN A 1 2   ? 215.319 260.350 219.739 1.00 318.61 ? 259 GLN C CG  1 
ATOM   16   C CD  . GLN A 1 2   ? 213.831 260.527 219.971 1.00 318.71 ? 259 GLN C CD  1 
ATOM   17   O OE1 . GLN A 1 2   ? 213.016 259.754 219.467 1.00 318.79 ? 259 GLN C OE1 1 
ATOM   18   N NE2 . GLN A 1 2   ? 213.469 261.548 220.739 1.00 318.59 ? 259 GLN C NE2 1 
ATOM   19   N N   . GLU A 1 3   ? 218.066 256.658 219.733 1.00 317.13 ? 260 GLU C N   1 
ATOM   20   C CA  . GLU A 1 3   ? 218.424 255.719 220.792 1.00 316.62 ? 260 GLU C CA  1 
ATOM   21   C C   . GLU A 1 3   ? 219.490 256.300 221.712 1.00 316.57 ? 260 GLU C C   1 
ATOM   22   O O   . GLU A 1 3   ? 219.437 256.112 222.934 1.00 316.68 ? 260 GLU C O   1 
ATOM   23   C CB  . GLU A 1 3   ? 218.898 254.400 220.182 1.00 316.48 ? 260 GLU C CB  1 
ATOM   24   C CG  . GLU A 1 3   ? 218.153 254.003 218.918 1.00 316.56 ? 260 GLU C CG  1 
ATOM   25   C CD  . GLU A 1 3   ? 218.959 253.076 218.031 1.00 316.42 ? 260 GLU C CD  1 
ATOM   26   O OE1 . GLU A 1 3   ? 220.076 252.688 218.433 1.00 316.50 ? 260 GLU C OE1 1 
ATOM   27   O OE2 . GLU A 1 3   ? 218.477 252.736 216.930 1.00 316.40 ? 260 GLU C OE2 1 
ATOM   28   N N   . LEU A 1 4   ? 220.473 257.003 221.142 1.00 311.92 ? 261 LEU C N   1 
ATOM   29   C CA  . LEU A 1 4   ? 221.477 257.667 221.966 1.00 311.42 ? 261 LEU C CA  1 
ATOM   30   C C   . LEU A 1 4   ? 220.836 258.705 222.879 1.00 311.45 ? 261 LEU C C   1 
ATOM   31   O O   . LEU A 1 4   ? 221.184 258.800 224.061 1.00 311.32 ? 261 LEU C O   1 
ATOM   32   C CB  . LEU A 1 4   ? 222.542 258.311 221.079 1.00 311.17 ? 261 LEU C CB  1 
ATOM   33   C CG  . LEU A 1 4   ? 223.163 257.409 220.011 1.00 311.08 ? 261 LEU C CG  1 
ATOM   34   C CD1 . LEU A 1 4   ? 224.127 258.196 219.136 1.00 310.87 ? 261 LEU C CD1 1 
ATOM   35   C CD2 . LEU A 1 4   ? 223.863 256.220 220.652 1.00 310.98 ? 261 LEU C CD2 1 
ATOM   36   N N   . ARG A 1 5   ? 219.896 259.491 222.349 1.00 305.11 ? 262 ARG C N   1 
ATOM   37   C CA  . ARG A 1 5   ? 219.142 260.405 223.198 1.00 304.42 ? 262 ARG C CA  1 
ATOM   38   C C   . ARG A 1 5   ? 218.155 259.656 224.084 1.00 304.05 ? 262 ARG C C   1 
ATOM   39   O O   . ARG A 1 5   ? 217.819 260.130 225.176 1.00 303.32 ? 262 ARG C O   1 
ATOM   40   C CB  . ARG A 1 5   ? 218.413 261.439 222.341 1.00 304.25 ? 262 ARG C CB  1 
ATOM   41   C CG  . ARG A 1 5   ? 219.332 262.457 221.688 1.00 304.29 ? 262 ARG C CG  1 
ATOM   42   C CD  . ARG A 1 5   ? 218.545 263.603 221.076 1.00 304.37 ? 262 ARG C CD  1 
ATOM   43   N NE  . ARG A 1 5   ? 219.419 264.635 220.532 1.00 304.52 ? 262 ARG C NE  1 
ATOM   44   C CZ  . ARG A 1 5   ? 218.994 265.748 219.951 1.00 304.19 ? 262 ARG C CZ  1 
ATOM   45   N NH1 . ARG A 1 5   ? 217.703 266.009 219.818 1.00 304.24 ? 262 ARG C NH1 1 
ATOM   46   N NH2 . ARG A 1 5   ? 219.885 266.622 219.490 1.00 303.96 ? 262 ARG C NH2 1 
ATOM   47   N N   . GLU A 1 6   ? 217.683 258.489 223.635 1.00 291.29 ? 263 GLU C N   1 
ATOM   48   C CA  . GLU A 1 6   ? 216.763 257.701 224.448 1.00 289.90 ? 263 GLU C CA  1 
ATOM   49   C C   . GLU A 1 6   ? 217.427 257.198 225.722 1.00 289.10 ? 263 GLU C C   1 
ATOM   50   O O   . GLU A 1 6   ? 216.770 257.114 226.764 1.00 287.84 ? 263 GLU C O   1 
ATOM   51   C CB  . GLU A 1 6   ? 216.213 256.525 223.641 1.00 290.04 ? 263 GLU C CB  1 
ATOM   52   C CG  . GLU A 1 6   ? 214.898 256.820 222.936 1.00 289.79 ? 263 GLU C CG  1 
ATOM   53   C CD  . GLU A 1 6   ? 214.524 255.752 221.928 1.00 289.81 ? 263 GLU C CD  1 
ATOM   54   O OE1 . GLU A 1 6   ? 215.349 254.847 221.684 1.00 290.05 ? 263 GLU C OE1 1 
ATOM   55   O OE2 . GLU A 1 6   ? 213.405 255.819 221.378 1.00 289.67 ? 263 GLU C OE2 1 
ATOM   56   N N   . MET A 1 7   ? 218.715 256.851 225.661 1.00 272.04 ? 264 MET C N   1 
ATOM   57   C CA  . MET A 1 7   ? 219.405 256.405 226.869 1.00 271.11 ? 264 MET C CA  1 
ATOM   58   C C   . MET A 1 7   ? 219.458 257.521 227.906 1.00 269.86 ? 264 MET C C   1 
ATOM   59   O O   . MET A 1 7   ? 219.225 257.284 229.097 1.00 268.76 ? 264 MET C O   1 
ATOM   60   C CB  . MET A 1 7   ? 220.805 255.884 226.510 1.00 271.61 ? 264 MET C CB  1 
ATOM   61   C CG  . MET A 1 7   ? 221.927 256.004 227.566 1.00 271.05 ? 264 MET C CG  1 
ATOM   62   S SD  . MET A 1 7   ? 222.543 257.629 228.075 1.00 271.95 ? 264 MET C SD  1 
ATOM   63   C CE  . MET A 1 7   ? 223.139 258.277 226.517 1.00 270.53 ? 264 MET C CE  1 
ATOM   64   N N   . ALA A 1 8   ? 219.757 258.747 227.468 1.00 248.47 ? 265 ALA C N   1 
ATOM   65   C CA  . ALA A 1 8   ? 219.748 259.885 228.383 1.00 247.01 ? 265 ALA C CA  1 
ATOM   66   C C   . ALA A 1 8   ? 218.345 260.161 228.908 1.00 245.68 ? 265 ALA C C   1 
ATOM   67   O O   . ALA A 1 8   ? 218.166 260.476 230.091 1.00 245.42 ? 265 ALA C O   1 
ATOM   68   C CB  . ALA A 1 8   ? 220.317 261.122 227.689 1.00 246.95 ? 265 ALA C CB  1 
ATOM   69   N N   . TRP A 1 9   ? 217.338 260.045 228.042 1.00 228.27 ? 266 TRP C N   1 
ATOM   70   C CA  . TRP A 1 9   ? 215.967 260.312 228.457 1.00 227.93 ? 266 TRP C CA  1 
ATOM   71   C C   . TRP A 1 9   ? 215.520 259.282 229.491 1.00 227.91 ? 266 TRP C C   1 
ATOM   72   O O   . TRP A 1 9   ? 214.751 259.594 230.407 1.00 227.83 ? 266 TRP C O   1 
ATOM   73   C CB  . TRP A 1 9   ? 215.068 260.302 227.215 1.00 228.28 ? 266 TRP C CB  1 
ATOM   74   C CG  . TRP A 1 9   ? 213.605 259.997 227.396 1.00 228.63 ? 266 TRP C CG  1 
ATOM   75   C CD1 . TRP A 1 9   ? 212.834 259.225 226.576 1.00 229.02 ? 266 TRP C CD1 1 
ATOM   76   C CD2 . TRP A 1 9   ? 212.695 260.612 228.326 1.00 228.49 ? 266 TRP C CD2 1 
ATOM   77   N NE1 . TRP A 1 9   ? 211.530 259.228 227.004 1.00 229.38 ? 266 TRP C NE1 1 
ATOM   78   C CE2 . TRP A 1 9   ? 211.415 260.082 228.068 1.00 229.07 ? 266 TRP C CE2 1 
ATOM   79   C CE3 . TRP A 1 9   ? 212.846 261.522 229.377 1.00 228.19 ? 266 TRP C CE3 1 
ATOM   80   C CZ2 . TRP A 1 9   ? 210.297 260.427 228.824 1.00 228.74 ? 266 TRP C CZ2 1 
ATOM   81   C CZ3 . TRP A 1 9   ? 211.735 261.860 230.128 1.00 227.81 ? 266 TRP C CZ3 1 
ATOM   82   C CH2 . TRP A 1 9   ? 210.478 261.315 229.847 1.00 227.91 ? 266 TRP C CH2 1 
ATOM   83   N N   . SER A 1 10  ? 216.015 258.047 229.373 1.00 218.61 ? 267 SER C N   1 
ATOM   84   C CA  . SER A 1 10  ? 215.691 257.012 230.351 1.00 217.75 ? 267 SER C CA  1 
ATOM   85   C C   . SER A 1 10  ? 216.442 257.220 231.660 1.00 216.90 ? 267 SER C C   1 
ATOM   86   O O   . SER A 1 10  ? 215.865 257.073 232.749 1.00 216.71 ? 267 SER C O   1 
ATOM   87   C CB  . SER A 1 10  ? 216.003 255.632 229.773 1.00 218.14 ? 267 SER C CB  1 
ATOM   88   O OG  . SER A 1 10  ? 217.380 255.327 229.907 1.00 218.06 ? 267 SER C OG  1 
ATOM   89   N N   . THR A 1 11  ? 217.734 257.550 231.582 1.00 203.81 ? 268 THR C N   1 
ATOM   90   C CA  . THR A 1 11  ? 218.498 257.702 232.812 1.00 203.45 ? 268 THR C CA  1 
ATOM   91   C C   . THR A 1 11  ? 218.032 258.924 233.587 1.00 202.17 ? 268 THR C C   1 
ATOM   92   O O   . THR A 1 11  ? 218.104 258.944 234.819 1.00 201.56 ? 268 THR C O   1 
ATOM   93   C CB  . THR A 1 11  ? 220.002 257.772 232.535 1.00 203.88 ? 268 THR C CB  1 
ATOM   94   O OG1 . THR A 1 11  ? 220.704 257.898 233.777 1.00 203.44 ? 268 THR C OG1 1 
ATOM   95   C CG2 . THR A 1 11  ? 220.344 258.968 231.686 1.00 204.33 ? 268 THR C CG2 1 
ATOM   96   N N   . MET A 1 12  ? 217.516 259.942 232.893 1.00 196.64 ? 269 MET C N   1 
ATOM   97   C CA  . MET A 1 12  ? 217.008 261.102 233.614 1.00 196.31 ? 269 MET C CA  1 
ATOM   98   C C   . MET A 1 12  ? 215.789 260.734 234.455 1.00 196.36 ? 269 MET C C   1 
ATOM   99   O O   . MET A 1 12  ? 215.699 261.132 235.623 1.00 197.02 ? 269 MET C O   1 
ATOM   100  C CB  . MET A 1 12  ? 216.732 262.257 232.637 1.00 197.57 ? 269 MET C CB  1 
ATOM   101  C CG  . MET A 1 12  ? 215.423 262.274 231.832 1.00 198.53 ? 269 MET C CG  1 
ATOM   102  S SD  . MET A 1 12  ? 213.868 262.456 232.734 1.00 199.23 ? 269 MET C SD  1 
ATOM   103  C CE  . MET A 1 12  ? 214.190 263.955 233.660 1.00 198.22 ? 269 MET C CE  1 
ATOM   104  N N   . LYS A 1 13  ? 214.855 259.946 233.904 1.00 190.74 ? 270 LYS C N   1 
ATOM   105  C CA  . LYS A 1 13  ? 213.713 259.548 234.723 1.00 191.15 ? 270 LYS C CA  1 
ATOM   106  C C   . LYS A 1 13  ? 214.141 258.616 235.847 1.00 189.20 ? 270 LYS C C   1 
ATOM   107  O O   . LYS A 1 13  ? 213.637 258.728 236.972 1.00 187.09 ? 270 LYS C O   1 
ATOM   108  C CB  . LYS A 1 13  ? 212.600 258.879 233.909 1.00 190.72 ? 270 LYS C CB  1 
ATOM   109  C CG  . LYS A 1 13  ? 212.952 258.132 232.639 1.00 190.81 ? 270 LYS C CG  1 
ATOM   110  C CD  . LYS A 1 13  ? 211.663 257.926 231.841 1.00 191.45 ? 270 LYS C CD  1 
ATOM   111  C CE  . LYS A 1 13  ? 211.865 257.211 230.517 1.00 191.95 ? 270 LYS C CE  1 
ATOM   112  N NZ  . LYS A 1 13  ? 212.805 257.895 229.612 1.00 193.63 ? 270 LYS C NZ  1 
ATOM   113  N N   . GLN A 1 14  ? 215.056 257.679 235.572 1.00 173.13 ? 271 GLN C N   1 
ATOM   114  C CA  . GLN A 1 14  ? 215.409 256.756 236.645 1.00 171.71 ? 271 GLN C CA  1 
ATOM   115  C C   . GLN A 1 14  ? 216.164 257.481 237.753 1.00 171.80 ? 271 GLN C C   1 
ATOM   116  O O   . GLN A 1 14  ? 215.987 257.160 238.932 1.00 173.74 ? 271 GLN C O   1 
ATOM   117  C CB  . GLN A 1 14  ? 216.173 255.536 236.095 1.00 173.09 ? 271 GLN C CB  1 
ATOM   118  C CG  . GLN A 1 14  ? 217.601 255.666 235.522 1.00 174.03 ? 271 GLN C CG  1 
ATOM   119  C CD  . GLN A 1 14  ? 218.608 256.332 236.443 1.00 174.51 ? 271 GLN C CD  1 
ATOM   120  O OE1 . GLN A 1 14  ? 218.808 255.894 237.576 1.00 174.45 ? 271 GLN C OE1 1 
ATOM   121  N NE2 . GLN A 1 14  ? 219.265 257.375 235.955 1.00 175.89 ? 271 GLN C NE2 1 
ATOM   122  N N   . GLU A 1 15  ? 216.938 258.513 237.406 1.00 154.08 ? 272 GLU C N   1 
ATOM   123  C CA  . GLU A 1 15  ? 217.651 259.277 238.421 1.00 152.75 ? 272 GLU C CA  1 
ATOM   124  C C   . GLU A 1 15  ? 216.703 260.183 239.196 1.00 151.04 ? 272 GLU C C   1 
ATOM   125  O O   . GLU A 1 15  ? 216.880 260.385 240.402 1.00 150.43 ? 272 GLU C O   1 
ATOM   126  C CB  . GLU A 1 15  ? 218.770 260.087 237.768 1.00 153.22 ? 272 GLU C CB  1 
ATOM   127  C CG  . GLU A 1 15  ? 219.555 260.967 238.721 1.00 152.45 ? 272 GLU C CG  1 
ATOM   128  C CD  . GLU A 1 15  ? 219.118 262.414 238.665 1.00 153.27 ? 272 GLU C CD  1 
ATOM   129  O OE1 . GLU A 1 15  ? 218.179 262.724 237.903 1.00 153.90 ? 272 GLU C OE1 1 
ATOM   130  O OE2 . GLU A 1 15  ? 219.713 263.243 239.385 1.00 154.31 ? 272 GLU C OE2 1 
ATOM   131  N N   . GLN A 1 16  ? 215.688 260.737 238.525 1.00 149.84 ? 273 GLN C N   1 
ATOM   132  C CA  . GLN A 1 16  ? 214.713 261.548 239.245 1.00 149.44 ? 273 GLN C CA  1 
ATOM   133  C C   . GLN A 1 16  ? 213.885 260.693 240.192 1.00 150.25 ? 273 GLN C C   1 
ATOM   134  O O   . GLN A 1 16  ? 213.528 261.150 241.282 1.00 150.57 ? 273 GLN C O   1 
ATOM   135  C CB  . GLN A 1 16  ? 213.872 262.361 238.237 1.00 151.37 ? 273 GLN C CB  1 
ATOM   136  C CG  . GLN A 1 16  ? 212.706 261.722 237.420 1.00 153.83 ? 273 GLN C CG  1 
ATOM   137  C CD  . GLN A 1 16  ? 211.584 261.036 238.199 1.00 153.95 ? 273 GLN C CD  1 
ATOM   138  O OE1 . GLN A 1 16  ? 211.386 261.268 239.390 1.00 154.25 ? 273 GLN C OE1 1 
ATOM   139  N NE2 . GLN A 1 16  ? 210.840 260.179 237.508 1.00 153.23 ? 273 GLN C NE2 1 
ATOM   140  N N   . SER A 1 17  ? 213.574 259.455 239.803 1.00 138.36 ? 274 SER C N   1 
ATOM   141  C CA  . SER A 1 17  ? 212.820 258.569 240.679 1.00 135.89 ? 274 SER C CA  1 
ATOM   142  C C   . SER A 1 17  ? 213.679 257.934 241.764 1.00 133.44 ? 274 SER C C   1 
ATOM   143  O O   . SER A 1 17  ? 213.137 257.504 242.787 1.00 131.40 ? 274 SER C O   1 
ATOM   144  C CB  . SER A 1 17  ? 212.139 257.469 239.863 1.00 138.59 ? 274 SER C CB  1 
ATOM   145  O OG  . SER A 1 17  ? 211.533 256.512 240.714 1.00 137.74 ? 274 SER C OG  1 
ATOM   146  N N   . THR A 1 18  ? 214.996 257.860 241.566 1.00 125.75 ? 275 THR C N   1 
ATOM   147  C CA  . THR A 1 18  ? 215.858 257.258 242.578 1.00 125.33 ? 275 THR C CA  1 
ATOM   148  C C   . THR A 1 18  ? 215.949 258.130 243.824 1.00 126.39 ? 275 THR C C   1 
ATOM   149  O O   . THR A 1 18  ? 215.600 257.688 244.927 1.00 128.80 ? 275 THR C O   1 
ATOM   150  C CB  . THR A 1 18  ? 217.253 257.009 242.004 1.00 123.76 ? 275 THR C CB  1 
ATOM   151  N N   . ARG A 1 19  ? 216.414 259.373 243.666 1.00 114.00 ? 276 ARG C N   1 
ATOM   152  C CA  . ARG A 1 19  ? 216.781 260.174 244.827 1.00 111.75 ? 276 ARG C CA  1 
ATOM   153  C C   . ARG A 1 19  ? 215.582 260.554 245.682 1.00 113.47 ? 276 ARG C C   1 
ATOM   154  O O   . ARG A 1 19  ? 215.728 260.691 246.897 1.00 115.95 ? 276 ARG C O   1 
ATOM   155  C CB  . ARG A 1 19  ? 217.521 261.445 244.410 1.00 114.19 ? 276 ARG C CB  1 
ATOM   156  C CG  . ARG A 1 19  ? 218.873 261.207 243.771 1.00 116.46 ? 276 ARG C CG  1 
ATOM   157  C CD  . ARG A 1 19  ? 219.396 262.409 242.967 1.00 120.52 ? 276 ARG C CD  1 
ATOM   158  N NE  . ARG A 1 19  ? 218.670 262.710 241.736 1.00 122.88 ? 276 ARG C NE  1 
ATOM   159  C CZ  . ARG A 1 19  ? 217.532 263.390 241.666 1.00 122.10 ? 276 ARG C CZ  1 
ATOM   160  N NH1 . ARG A 1 19  ? 216.986 263.945 242.736 1.00 120.92 ? 276 ARG C NH1 1 
ATOM   161  N NH2 . ARG A 1 19  ? 216.947 263.554 240.484 1.00 122.30 ? 276 ARG C NH2 1 
ATOM   162  N N   . VAL A 1 20  ? 214.401 260.734 245.087 1.00 92.13  ? 277 VAL C N   1 
ATOM   163  C CA  . VAL A 1 20  ? 213.238 261.112 245.889 1.00 91.00  ? 277 VAL C CA  1 
ATOM   164  C C   . VAL A 1 20  ? 212.884 260.004 246.874 1.00 91.34  ? 277 VAL C C   1 
ATOM   165  O O   . VAL A 1 20  ? 212.718 260.248 248.079 1.00 91.17  ? 277 VAL C O   1 
ATOM   166  C CB  . VAL A 1 20  ? 212.050 261.476 244.979 1.00 91.26  ? 277 VAL C CB  1 
ATOM   167  C CG1 . VAL A 1 20  ? 211.833 260.414 243.911 1.00 93.69  ? 277 VAL C CG1 1 
ATOM   168  C CG2 . VAL A 1 20  ? 210.790 261.665 245.807 1.00 90.11  ? 277 VAL C CG2 1 
ATOM   169  N N   . LYS A 1 21  ? 212.778 258.768 246.385 1.00 87.62  ? 278 LYS C N   1 
ATOM   170  C CA  . LYS A 1 21  ? 212.490 257.647 247.267 1.00 85.18  ? 278 LYS C CA  1 
ATOM   171  C C   . LYS A 1 21  ? 213.637 257.383 248.225 1.00 80.02  ? 278 LYS C C   1 
ATOM   172  O O   . LYS A 1 21  ? 213.397 257.033 249.385 1.00 81.12  ? 278 LYS C O   1 
ATOM   173  C CB  . LYS A 1 21  ? 212.179 256.393 246.450 1.00 85.85  ? 278 LYS C CB  1 
ATOM   174  C CG  . LYS A 1 21  ? 210.749 256.341 245.937 1.00 89.92  ? 278 LYS C CG  1 
ATOM   175  C CD  . LYS A 1 21  ? 209.751 256.525 247.070 1.00 87.94  ? 278 LYS C CD  1 
ATOM   176  C CE  . LYS A 1 21  ? 208.605 257.438 246.662 1.00 84.09  ? 278 LYS C CE  1 
ATOM   177  N NZ  . LYS A 1 21  ? 208.996 258.874 246.684 1.00 84.10  ? 278 LYS C NZ  1 
ATOM   178  N N   . LEU A 1 22  ? 214.880 257.563 247.771 1.00 78.45  ? 279 LEU C N   1 
ATOM   179  C CA  . LEU A 1 22  ? 216.015 257.397 248.669 1.00 80.37  ? 279 LEU C CA  1 
ATOM   180  C C   . LEU A 1 22  ? 215.949 258.389 249.823 1.00 84.76  ? 279 LEU C C   1 
ATOM   181  O O   . LEU A 1 22  ? 216.189 258.025 250.978 1.00 89.80  ? 279 LEU C O   1 
ATOM   182  C CB  . LEU A 1 22  ? 217.323 257.553 247.896 1.00 80.96  ? 279 LEU C CB  1 
ATOM   183  C CG  . LEU A 1 22  ? 218.598 257.261 248.687 1.00 83.04  ? 279 LEU C CG  1 
ATOM   184  C CD1 . LEU A 1 22  ? 218.716 255.775 248.969 1.00 81.71  ? 279 LEU C CD1 1 
ATOM   185  C CD2 . LEU A 1 22  ? 219.821 257.767 247.943 1.00 81.63  ? 279 LEU C CD2 1 
ATOM   186  N N   . LEU A 1 23  ? 215.598 259.642 249.533 1.00 70.14  ? 280 LEU C N   1 
ATOM   187  C CA  . LEU A 1 23  ? 215.538 260.663 250.572 1.00 65.99  ? 280 LEU C CA  1 
ATOM   188  C C   . LEU A 1 23  ? 214.377 260.419 251.526 1.00 65.78  ? 280 LEU C C   1 
ATOM   189  O O   . LEU A 1 23  ? 214.520 260.593 252.743 1.00 66.07  ? 280 LEU C O   1 
ATOM   190  C CB  . LEU A 1 23  ? 215.432 262.047 249.935 1.00 66.99  ? 280 LEU C CB  1 
ATOM   191  C CG  . LEU A 1 23  ? 216.727 262.858 249.892 1.00 68.78  ? 280 LEU C CG  1 
ATOM   192  C CD1 . LEU A 1 23  ? 217.044 263.414 251.268 1.00 75.72  ? 280 LEU C CD1 1 
ATOM   193  C CD2 . LEU A 1 23  ? 217.881 262.017 249.374 1.00 65.77  ? 280 LEU C CD2 1 
ATOM   194  N N   . GLU A 1 24  ? 213.216 260.019 251.000 1.00 57.15  ? 281 GLU C N   1 
ATOM   195  C CA  . GLU A 1 24  ? 212.096 259.707 251.884 1.00 58.80  ? 281 GLU C CA  1 
ATOM   196  C C   . GLU A 1 24  ? 212.420 258.523 252.789 1.00 65.47  ? 281 GLU C C   1 
ATOM   197  O O   . GLU A 1 24  ? 212.139 258.556 253.996 1.00 66.80  ? 281 GLU C O   1 
ATOM   198  C CB  . GLU A 1 24  ? 210.839 259.432 251.062 1.00 58.05  ? 281 GLU C CB  1 
ATOM   199  C CG  . GLU A 1 24  ? 209.595 259.193 251.898 1.00 57.72  ? 281 GLU C CG  1 
ATOM   200  C CD  . GLU A 1 24  ? 208.920 260.479 252.321 1.00 62.63  ? 281 GLU C CD  1 
ATOM   201  O OE1 . GLU A 1 24  ? 209.470 261.186 253.187 1.00 62.89  ? 281 GLU C OE1 1 
ATOM   202  O OE2 . GLU A 1 24  ? 207.834 260.784 251.787 1.00 69.46  ? 281 GLU C OE2 1 
ATOM   203  N N   . GLU A 1 25  ? 213.027 257.476 252.227 1.00 71.31  ? 282 GLU C N   1 
ATOM   204  C CA  . GLU A 1 25  ? 213.420 256.322 253.025 1.00 63.32  ? 282 GLU C CA  1 
ATOM   205  C C   . GLU A 1 25  ? 214.464 256.704 254.065 1.00 60.12  ? 282 GLU C C   1 
ATOM   206  O O   . GLU A 1 25  ? 214.433 256.209 255.195 1.00 62.54  ? 282 GLU C O   1 
ATOM   207  C CB  . GLU A 1 25  ? 213.942 255.217 252.108 1.00 65.57  ? 282 GLU C CB  1 
ATOM   208  C CG  . GLU A 1 25  ? 214.366 253.950 252.819 1.00 65.55  ? 282 GLU C CG  1 
ATOM   209  C CD  . GLU A 1 25  ? 215.588 253.319 252.188 1.00 66.36  ? 282 GLU C CD  1 
ATOM   210  O OE1 . GLU A 1 25  ? 216.086 253.862 251.181 1.00 66.98  ? 282 GLU C OE1 1 
ATOM   211  O OE2 . GLU A 1 25  ? 216.052 252.279 252.699 1.00 68.42  ? 282 GLU C OE2 1 
ATOM   212  N N   . LEU A 1 26  ? 215.396 257.586 253.701 1.00 55.98  ? 283 LEU C N   1 
ATOM   213  C CA  . LEU A 1 26  ? 216.409 258.033 254.649 1.00 58.12  ? 283 LEU C CA  1 
ATOM   214  C C   . LEU A 1 26  ? 215.786 258.826 255.792 1.00 63.03  ? 283 LEU C C   1 
ATOM   215  O O   . LEU A 1 26  ? 216.201 258.693 256.947 1.00 65.59  ? 283 LEU C O   1 
ATOM   216  C CB  . LEU A 1 26  ? 217.460 258.868 253.922 1.00 59.07  ? 283 LEU C CB  1 
ATOM   217  C CG  . LEU A 1 26  ? 218.632 259.401 254.741 1.00 64.91  ? 283 LEU C CG  1 
ATOM   218  C CD1 . LEU A 1 26  ? 219.158 258.329 255.679 1.00 59.46  ? 283 LEU C CD1 1 
ATOM   219  C CD2 . LEU A 1 26  ? 219.728 259.904 253.819 1.00 64.18  ? 283 LEU C CD2 1 
ATOM   220  N N   . ARG A 1 27  ? 214.792 259.662 255.490 1.00 58.91  ? 284 ARG C N   1 
ATOM   221  C CA  . ARG A 1 27  ? 214.123 260.412 256.549 1.00 55.61  ? 284 ARG C CA  1 
ATOM   222  C C   . ARG A 1 27  ? 213.341 259.485 257.474 1.00 56.64  ? 284 ARG C C   1 
ATOM   223  O O   . ARG A 1 27  ? 213.305 259.693 258.695 1.00 63.89  ? 284 ARG C O   1 
ATOM   224  C CB  . ARG A 1 27  ? 213.206 261.472 255.943 1.00 58.38  ? 284 ARG C CB  1 
ATOM   225  C CG  . ARG A 1 27  ? 213.224 262.792 256.687 1.00 56.64  ? 284 ARG C CG  1 
ATOM   226  C CD  . ARG A 1 27  ? 212.031 263.647 256.311 1.00 55.65  ? 284 ARG C CD  1 
ATOM   227  N NE  . ARG A 1 27  ? 210.808 262.861 256.222 1.00 56.97  ? 284 ARG C NE  1 
ATOM   228  C CZ  . ARG A 1 27  ? 210.143 262.388 257.266 1.00 66.28  ? 284 ARG C CZ  1 
ATOM   229  N NH1 . ARG A 1 27  ? 210.550 262.613 258.504 1.00 65.43  ? 284 ARG C NH1 1 
ATOM   230  N NH2 . ARG A 1 27  ? 209.041 261.672 257.064 1.00 71.67  ? 284 ARG C NH2 1 
ATOM   231  N N   . TRP A 1 28  ? 212.700 258.458 256.915 1.00 55.26  ? 285 TRP C N   1 
ATOM   232  C CA  . TRP A 1 28  ? 212.048 257.475 257.775 1.00 55.88  ? 285 TRP C CA  1 
ATOM   233  C C   . TRP A 1 28  ? 213.055 256.679 258.600 1.00 55.69  ? 285 TRP C C   1 
ATOM   234  O O   . TRP A 1 28  ? 212.765 256.336 259.750 1.00 51.64  ? 285 TRP C O   1 
ATOM   235  C CB  . TRP A 1 28  ? 211.176 256.535 256.945 1.00 62.48  ? 285 TRP C CB  1 
ATOM   236  C CG  . TRP A 1 28  ? 209.941 257.188 256.393 1.00 61.36  ? 285 TRP C CG  1 
ATOM   237  C CD1 . TRP A 1 28  ? 209.587 257.287 255.081 1.00 62.83  ? 285 TRP C CD1 1 
ATOM   238  C CD2 . TRP A 1 28  ? 208.899 257.832 257.137 1.00 55.83  ? 285 TRP C CD2 1 
ATOM   239  N NE1 . TRP A 1 28  ? 208.392 257.948 254.961 1.00 63.05  ? 285 TRP C NE1 1 
ATOM   240  C CE2 . TRP A 1 28  ? 207.948 258.294 256.209 1.00 57.35  ? 285 TRP C CE2 1 
ATOM   241  C CE3 . TRP A 1 28  ? 208.677 258.059 258.497 1.00 58.41  ? 285 TRP C CE3 1 
ATOM   242  C CZ2 . TRP A 1 28  ? 206.796 258.970 256.597 1.00 55.86  ? 285 TRP C CZ2 1 
ATOM   243  C CZ3 . TRP A 1 28  ? 207.533 258.731 258.879 1.00 56.79  ? 285 TRP C CZ3 1 
ATOM   244  C CH2 . TRP A 1 28  ? 206.607 259.178 257.933 1.00 53.97  ? 285 TRP C CH2 1 
ATOM   245  N N   . ARG A 1 29  ? 214.229 256.384 258.039 1.00 55.59  ? 286 ARG C N   1 
ATOM   246  C CA  . ARG A 1 29  ? 215.308 255.797 258.826 1.00 53.26  ? 286 ARG C CA  1 
ATOM   247  C C   . ARG A 1 29  ? 215.712 256.716 259.968 1.00 54.75  ? 286 ARG C C   1 
ATOM   248  O O   . ARG A 1 29  ? 216.000 256.247 261.075 1.00 58.38  ? 286 ARG C O   1 
ATOM   249  C CB  . ARG A 1 29  ? 216.517 255.517 257.935 1.00 52.41  ? 286 ARG C CB  1 
ATOM   250  C CG  . ARG A 1 29  ? 216.754 254.056 257.612 1.00 54.06  ? 286 ARG C CG  1 
ATOM   251  C CD  . ARG A 1 29  ? 215.821 253.569 256.522 1.00 53.05  ? 286 ARG C CD  1 
ATOM   252  N NE  . ARG A 1 29  ? 216.295 252.333 255.912 1.00 51.68  ? 286 ARG C NE  1 
ATOM   253  C CZ  . ARG A 1 29  ? 216.249 251.143 256.493 1.00 56.62  ? 286 ARG C CZ  1 
ATOM   254  N NH1 . ARG A 1 29  ? 215.745 250.984 257.705 1.00 55.61  ? 286 ARG C NH1 1 
ATOM   255  N NH2 . ARG A 1 29  ? 216.717 250.084 255.840 1.00 59.83  ? 286 ARG C NH2 1 
ATOM   256  N N   . SER A 1 30  ? 215.756 258.021 259.705 1.00 59.33  ? 287 SER C N   1 
ATOM   257  C CA  . SER A 1 30  ? 216.040 258.999 260.749 1.00 58.87  ? 287 SER C CA  1 
ATOM   258  C C   . SER A 1 30  ? 215.020 258.911 261.871 1.00 54.34  ? 287 SER C C   1 
ATOM   259  O O   . SER A 1 30  ? 215.381 258.802 263.048 1.00 54.13  ? 287 SER C O   1 
ATOM   260  C CB  . SER A 1 30  ? 216.036 260.407 260.159 1.00 63.15  ? 287 SER C CB  1 
ATOM   261  N N   . ILE A 1 31  ? 213.734 258.964 261.521 1.00 52.49  ? 288 ILE C N   1 
ATOM   262  C CA  . ILE A 1 31  ? 212.705 258.938 262.554 1.00 54.28  ? 288 ILE C CA  1 
ATOM   263  C C   . ILE A 1 31  ? 212.707 257.599 263.279 1.00 67.77  ? 288 ILE C C   1 
ATOM   264  O O   . ILE A 1 31  ? 212.279 257.514 264.436 1.00 69.62  ? 288 ILE C O   1 
ATOM   265  C CB  . ILE A 1 31  ? 211.319 259.269 261.970 1.00 53.31  ? 288 ILE C CB  1 
ATOM   266  C CG1 . ILE A 1 31  ? 210.380 259.738 263.080 1.00 48.77  ? 288 ILE C CG1 1 
ATOM   267  C CG2 . ILE A 1 31  ? 210.714 258.062 261.296 1.00 58.52  ? 288 ILE C CG2 1 
ATOM   268  C CD1 . ILE A 1 31  ? 210.937 260.867 263.911 1.00 54.79  ? 288 ILE C CD1 1 
ATOM   269  N N   . GLN A 1 32  ? 213.197 256.537 262.632 1.00 67.73  ? 289 GLN C N   1 
ATOM   270  C CA  . GLN A 1 32  ? 213.278 255.248 263.310 1.00 53.86  ? 289 GLN C CA  1 
ATOM   271  C C   . GLN A 1 32  ? 214.521 255.140 264.183 1.00 48.73  ? 289 GLN C C   1 
ATOM   272  O O   . GLN A 1 32  ? 214.438 254.679 265.326 1.00 51.04  ? 289 GLN C O   1 
ATOM   273  C CB  . GLN A 1 32  ? 213.257 254.107 262.300 1.00 46.93  ? 289 GLN C CB  1 
ATOM   274  C CG  . GLN A 1 32  ? 212.688 252.843 262.886 1.00 41.88  ? 289 GLN C CG  1 
ATOM   275  C CD  . GLN A 1 32  ? 213.077 251.611 262.118 1.00 50.56  ? 289 GLN C CD  1 
ATOM   276  O OE1 . GLN A 1 32  ? 213.942 251.651 261.245 1.00 49.06  ? 289 GLN C OE1 1 
ATOM   277  N NE2 . GLN A 1 32  ? 212.441 250.499 262.444 1.00 54.58  ? 289 GLN C NE2 1 
ATOM   278  N N   . TYR A 1 33  ? 215.677 255.562 263.671 1.00 48.34  ? 290 TYR C N   1 
ATOM   279  C CA  . TYR A 1 33  ? 216.906 255.513 264.453 1.00 47.60  ? 290 TYR C CA  1 
ATOM   280  C C   . TYR A 1 33  ? 216.909 256.496 265.614 1.00 58.23  ? 290 TYR C C   1 
ATOM   281  O O   . TYR A 1 33  ? 217.948 256.642 266.265 1.00 64.23  ? 290 TYR C O   1 
ATOM   282  C CB  . TYR A 1 33  ? 218.122 255.785 263.565 1.00 47.38  ? 290 TYR C CB  1 
ATOM   283  C CG  . TYR A 1 33  ? 218.439 254.701 262.562 1.00 45.91  ? 290 TYR C CG  1 
ATOM   284  C CD1 . TYR A 1 33  ? 217.720 253.516 262.533 1.00 50.50  ? 290 TYR C CD1 1 
ATOM   285  C CD2 . TYR A 1 33  ? 219.461 254.868 261.640 1.00 51.50  ? 290 TYR C CD2 1 
ATOM   286  C CE1 . TYR A 1 33  ? 218.011 252.529 261.612 1.00 55.23  ? 290 TYR C CE1 1 
ATOM   287  C CE2 . TYR A 1 33  ? 219.756 253.890 260.716 1.00 52.08  ? 290 TYR C CE2 1 
ATOM   288  C CZ  . TYR A 1 33  ? 219.031 252.722 260.707 1.00 53.46  ? 290 TYR C CZ  1 
ATOM   289  O OH  . TYR A 1 33  ? 219.328 251.744 259.788 1.00 48.75  ? 290 TYR C OH  1 
ATOM   290  N N   . ALA A 1 34  ? 215.793 257.182 265.876 1.00 51.49  ? 291 ALA C N   1 
ATOM   291  C CA  . ALA A 1 34  ? 215.742 258.122 266.990 1.00 45.76  ? 291 ALA C CA  1 
ATOM   292  C C   . ALA A 1 34  ? 216.003 257.417 268.313 1.00 50.74  ? 291 ALA C C   1 
ATOM   293  O O   . ALA A 1 34  ? 216.681 257.962 269.192 1.00 47.52  ? 291 ALA C O   1 
ATOM   294  C CB  . ALA A 1 34  ? 214.390 258.833 267.017 1.00 43.86  ? 291 ALA C CB  1 
ATOM   295  N N   . SER A 1 35  ? 215.476 256.206 268.474 1.00 51.94  ? 292 SER C N   1 
ATOM   296  C CA  . SER A 1 35  ? 215.765 255.410 269.655 1.00 50.27  ? 292 SER C CA  1 
ATOM   297  C C   . SER A 1 35  ? 217.213 254.920 269.613 1.00 50.93  ? 292 SER C C   1 
ATOM   298  O O   . SER A 1 35  ? 217.970 255.211 268.683 1.00 64.26  ? 292 SER C O   1 
ATOM   299  C CB  . SER A 1 35  ? 214.787 254.243 269.752 1.00 38.95  ? 292 SER C CB  1 
ATOM   300  O OG  . SER A 1 35  ? 214.524 253.701 268.472 1.00 39.83  ? 292 SER C OG  1 
ATOM   301  N N   . ARG A 1 36  ? 217.600 254.178 270.652 1.00 36.62  ? 293 ARG C N   1 
ATOM   302  C CA  . ARG A 1 36  ? 218.919 253.544 270.774 1.00 44.14  ? 293 ARG C CA  1 
ATOM   303  C C   . ARG A 1 36  ? 220.056 254.526 270.464 1.00 48.91  ? 293 ARG C C   1 
ATOM   304  O O   . ARG A 1 36  ? 220.856 254.341 269.546 1.00 56.53  ? 293 ARG C O   1 
ATOM   305  C CB  . ARG A 1 36  ? 218.996 252.271 269.911 1.00 51.66  ? 293 ARG C CB  1 
ATOM   306  C CG  . ARG A 1 36  ? 218.995 252.434 268.382 1.00 47.19  ? 293 ARG C CG  1 
ATOM   307  C CD  . ARG A 1 36  ? 218.056 251.454 267.704 1.00 54.04  ? 293 ARG C CD  1 
ATOM   308  N NE  . ARG A 1 36  ? 218.576 251.002 266.419 1.00 54.99  ? 293 ARG C NE  1 
ATOM   309  C CZ  . ARG A 1 36  ? 217.826 250.727 265.360 1.00 49.98  ? 293 ARG C CZ  1 
ATOM   310  N NH1 . ARG A 1 36  ? 216.511 250.860 265.392 1.00 52.79  ? 293 ARG C NH1 1 
ATOM   311  N NH2 . ARG A 1 36  ? 218.410 250.304 264.244 1.00 45.56  ? 293 ARG C NH2 1 
ATOM   312  N N   . GLY A 1 37  ? 220.141 255.572 271.277 1.00 47.34  ? 294 GLY C N   1 
ATOM   313  C CA  . GLY A 1 37  ? 221.028 256.696 271.012 1.00 54.82  ? 294 GLY C CA  1 
ATOM   314  C C   . GLY A 1 37  ? 222.155 256.835 272.021 1.00 56.18  ? 294 GLY C C   1 
ATOM   315  O O   . GLY A 1 37  ? 221.939 256.705 273.229 1.00 55.95  ? 294 GLY C O   1 
ATOM   316  N N   . GLU A 1 38  ? 223.353 257.108 271.506 1.00 71.14  ? 295 GLU C N   1 
ATOM   317  C CA  . GLU A 1 38  ? 224.527 257.424 272.310 1.00 65.93  ? 295 GLU C CA  1 
ATOM   318  C C   . GLU A 1 38  ? 225.573 258.044 271.394 1.00 67.76  ? 295 GLU C C   1 
ATOM   319  O O   . GLU A 1 38  ? 225.506 257.908 270.170 1.00 69.27  ? 295 GLU C O   1 
ATOM   320  C CB  . GLU A 1 38  ? 225.084 256.186 273.020 1.00 67.86  ? 295 GLU C CB  1 
ATOM   321  C CG  . GLU A 1 38  ? 225.999 255.339 272.162 1.00 71.42  ? 295 GLU C CG  1 
ATOM   322  C CD  . GLU A 1 38  ? 225.246 254.563 271.103 1.00 75.14  ? 295 GLU C CD  1 
ATOM   323  O OE1 . GLU A 1 38  ? 224.052 254.270 271.317 1.00 76.66  ? 295 GLU C OE1 1 
ATOM   324  O OE2 . GLU A 1 38  ? 225.848 254.246 270.056 1.00 77.90  ? 295 GLU C OE2 1 
ATOM   325  N N   . ARG A 1 39  ? 226.546 258.733 272.002 1.00 77.17  ? 296 ARG C N   1 
ATOM   326  C CA  . ARG A 1 39  ? 227.510 259.499 271.218 1.00 78.29  ? 296 ARG C CA  1 
ATOM   327  C C   . ARG A 1 39  ? 228.934 259.421 271.764 1.00 74.56  ? 296 ARG C C   1 
ATOM   328  O O   . ARG A 1 39  ? 229.735 260.325 271.499 1.00 74.04  ? 296 ARG C O   1 
ATOM   329  C CB  . ARG A 1 39  ? 227.068 260.969 271.124 1.00 78.27  ? 296 ARG C CB  1 
ATOM   330  C CG  . ARG A 1 39  ? 227.297 261.800 272.385 1.00 71.48  ? 296 ARG C CG  1 
ATOM   331  C CD  . ARG A 1 39  ? 226.185 261.616 273.399 1.00 75.78  ? 296 ARG C CD  1 
ATOM   332  N NE  . ARG A 1 39  ? 226.327 262.526 274.528 1.00 79.74  ? 296 ARG C NE  1 
ATOM   333  C CZ  . ARG A 1 39  ? 227.216 262.379 275.500 1.00 80.94  ? 296 ARG C CZ  1 
ATOM   334  N NH1 . ARG A 1 39  ? 228.059 261.360 275.518 1.00 78.37  ? 296 ARG C NH1 1 
ATOM   335  N NH2 . ARG A 1 39  ? 227.259 263.276 276.480 1.00 84.03  ? 296 ARG C NH2 1 
ATOM   336  N N   . HIS A 1 40  ? 229.285 258.350 272.481 1.00 84.08  ? 297 HIS C N   1 
ATOM   337  C CA  . HIS A 1 40  ? 230.549 258.323 273.214 1.00 89.83  ? 297 HIS C CA  1 
ATOM   338  C C   . HIS A 1 40  ? 231.743 258.519 272.285 1.00 93.49  ? 297 HIS C C   1 
ATOM   339  O O   . HIS A 1 40  ? 232.660 259.291 272.589 1.00 96.52  ? 297 HIS C O   1 
ATOM   340  C CB  . HIS A 1 40  ? 230.678 257.011 273.988 1.00 90.35  ? 297 HIS C CB  1 
ATOM   341  C CG  . HIS A 1 40  ? 230.460 255.790 273.150 1.00 93.35  ? 297 HIS C CG  1 
ATOM   342  N ND1 . HIS A 1 40  ? 229.209 255.263 272.916 1.00 96.53  ? 297 HIS C ND1 1 
ATOM   343  C CD2 . HIS A 1 40  ? 231.334 254.992 272.494 1.00 93.80  ? 297 HIS C CD2 1 
ATOM   344  C CE1 . HIS A 1 40  ? 229.321 254.192 272.150 1.00 93.02  ? 297 HIS C CE1 1 
ATOM   345  N NE2 . HIS A 1 40  ? 230.600 254.006 271.879 1.00 94.35  ? 297 HIS C NE2 1 
ATOM   346  N N   . SER A 1 41  ? 231.749 257.834 271.145 1.00 89.37  ? 298 SER C N   1 
ATOM   347  C CA  . SER A 1 41  ? 232.820 257.962 270.167 1.00 88.00  ? 298 SER C CA  1 
ATOM   348  C C   . SER A 1 41  ? 232.312 258.361 268.791 1.00 82.45  ? 298 SER C C   1 
ATOM   349  O O   . SER A 1 41  ? 233.082 258.332 267.827 1.00 83.21  ? 298 SER C O   1 
ATOM   350  C CB  . SER A 1 41  ? 233.606 256.650 270.065 1.00 92.19  ? 298 SER C CB  1 
ATOM   351  O OG  . SER A 1 41  ? 233.073 255.817 269.049 1.00 91.08  ? 298 SER C OG  1 
ATOM   352  N N   . ALA A 1 42  ? 231.039 258.735 268.682 1.00 79.53  ? 299 ALA C N   1 
ATOM   353  C CA  . ALA A 1 42  ? 230.432 258.983 267.380 1.00 87.33  ? 299 ALA C CA  1 
ATOM   354  C C   . ALA A 1 42  ? 231.081 260.162 266.662 1.00 85.02  ? 299 ALA C C   1 
ATOM   355  O O   . ALA A 1 42  ? 231.334 260.101 265.448 1.00 85.50  ? 299 ALA C O   1 
ATOM   356  C CB  . ALA A 1 42  ? 228.933 259.219 267.564 1.00 89.68  ? 299 ALA C CB  1 
ATOM   357  N N   . TYR A 1 43  ? 231.352 261.247 267.396 1.00 71.51  ? 300 TYR C N   1 
ATOM   358  C CA  . TYR A 1 43  ? 231.783 262.490 266.763 1.00 68.69  ? 300 TYR C CA  1 
ATOM   359  C C   . TYR A 1 43  ? 233.082 262.301 265.994 1.00 72.07  ? 300 TYR C C   1 
ATOM   360  O O   . TYR A 1 43  ? 233.157 262.618 264.803 1.00 74.73  ? 300 TYR C O   1 
ATOM   361  C CB  . TYR A 1 43  ? 231.937 263.589 267.814 1.00 64.28  ? 300 TYR C CB  1 
ATOM   362  N N   . ASN A 1 44  ? 234.106 261.761 266.643 1.00 79.41  ? 301 ASN C N   1 
ATOM   363  C CA  . ASN A 1 44  ? 235.355 261.490 265.949 1.00 79.95  ? 301 ASN C CA  1 
ATOM   364  C C   . ASN A 1 44  ? 235.256 260.280 265.032 1.00 76.71  ? 301 ASN C C   1 
ATOM   365  O O   . ASN A 1 44  ? 236.199 260.007 264.282 1.00 73.57  ? 301 ASN C O   1 
ATOM   366  C CB  . ASN A 1 44  ? 236.489 261.286 266.957 1.00 78.78  ? 301 ASN C CB  1 
ATOM   367  C CG  . ASN A 1 44  ? 237.856 261.468 266.336 1.00 74.49  ? 301 ASN C CG  1 
ATOM   368  O OD1 . ASN A 1 44  ? 238.498 260.502 265.926 1.00 78.61  ? 301 ASN C OD1 1 
ATOM   369  N ND2 . ASN A 1 44  ? 238.308 262.713 266.256 1.00 67.42  ? 301 ASN C ND2 1 
ATOM   370  N N   . GLU A 1 45  ? 234.140 259.553 265.078 1.00 77.96  ? 302 GLU C N   1 
ATOM   371  C CA  . GLU A 1 45  ? 233.986 258.380 264.227 1.00 76.14  ? 302 GLU C CA  1 
ATOM   372  C C   . GLU A 1 45  ? 233.520 258.769 262.830 1.00 73.86  ? 302 GLU C C   1 
ATOM   373  O O   . GLU A 1 45  ? 234.079 258.301 261.831 1.00 75.59  ? 302 GLU C O   1 
ATOM   374  C CB  . GLU A 1 45  ? 233.009 257.390 264.860 1.00 77.85  ? 302 GLU C CB  1 
ATOM   375  N N   . TRP A 1 46  ? 232.497 259.621 262.730 1.00 68.59  ? 303 TRP C N   1 
ATOM   376  C CA  . TRP A 1 46  ? 231.936 259.918 261.416 1.00 73.25  ? 303 TRP C CA  1 
ATOM   377  C C   . TRP A 1 46  ? 232.099 261.360 260.954 1.00 82.89  ? 303 TRP C C   1 
ATOM   378  O O   . TRP A 1 46  ? 231.835 261.638 259.779 1.00 80.52  ? 303 TRP C O   1 
ATOM   379  C CB  . TRP A 1 46  ? 230.447 259.553 261.358 1.00 69.49  ? 303 TRP C CB  1 
ATOM   380  C CG  . TRP A 1 46  ? 229.714 259.780 262.618 1.00 69.32  ? 303 TRP C CG  1 
ATOM   381  C CD1 . TRP A 1 46  ? 229.225 258.827 263.452 1.00 73.96  ? 303 TRP C CD1 1 
ATOM   382  C CD2 . TRP A 1 46  ? 229.369 261.041 263.199 1.00 70.62  ? 303 TRP C CD2 1 
ATOM   383  N NE1 . TRP A 1 46  ? 228.594 259.411 264.517 1.00 75.06  ? 303 TRP C NE1 1 
ATOM   384  C CE2 . TRP A 1 46  ? 228.673 260.772 264.389 1.00 72.33  ? 303 TRP C CE2 1 
ATOM   385  C CE3 . TRP A 1 46  ? 229.578 262.371 262.827 1.00 70.00  ? 303 TRP C CE3 1 
ATOM   386  C CZ2 . TRP A 1 46  ? 228.185 261.779 265.211 1.00 69.92  ? 303 TRP C CZ2 1 
ATOM   387  C CZ3 . TRP A 1 46  ? 229.098 263.369 263.645 1.00 73.90  ? 303 TRP C CZ3 1 
ATOM   388  C CH2 . TRP A 1 46  ? 228.410 263.068 264.824 1.00 77.53  ? 303 TRP C CH2 1 
ATOM   389  N N   . LYS A 1 47  ? 232.512 262.286 261.824 1.00 84.26  ? 304 LYS C N   1 
ATOM   390  C CA  . LYS A 1 47  ? 232.740 263.649 261.351 1.00 75.41  ? 304 LYS C CA  1 
ATOM   391  C C   . LYS A 1 47  ? 233.936 263.714 260.412 1.00 77.12  ? 304 LYS C C   1 
ATOM   392  O O   . LYS A 1 47  ? 234.037 264.639 259.599 1.00 79.73  ? 304 LYS C O   1 
ATOM   393  C CB  . LYS A 1 47  ? 232.931 264.608 262.526 1.00 69.06  ? 304 LYS C CB  1 
ATOM   394  C CG  . LYS A 1 47  ? 234.375 264.984 262.802 1.00 67.63  ? 304 LYS C CG  1 
ATOM   395  C CD  . LYS A 1 47  ? 234.510 265.712 264.125 1.00 72.43  ? 304 LYS C CD  1 
ATOM   396  C CE  . LYS A 1 47  ? 235.944 265.689 264.620 1.00 76.80  ? 304 LYS C CE  1 
ATOM   397  N NZ  . LYS A 1 47  ? 236.122 266.526 265.837 1.00 73.98  ? 304 LYS C NZ  1 
ATOM   398  N N   . LYS A 1 48  ? 234.845 262.743 260.506 1.00 72.70  ? 305 LYS C N   1 
ATOM   399  C CA  . LYS A 1 48  ? 235.981 262.695 259.599 1.00 71.18  ? 305 LYS C CA  1 
ATOM   400  C C   . LYS A 1 48  ? 235.713 261.808 258.392 1.00 71.00  ? 305 LYS C C   1 
ATOM   401  O O   . LYS A 1 48  ? 236.554 261.729 257.490 1.00 76.35  ? 305 LYS C O   1 
ATOM   402  C CB  . LYS A 1 48  ? 237.220 262.195 260.340 1.00 70.67  ? 305 LYS C CB  1 
ATOM   403  C CG  . LYS A 1 48  ? 237.531 262.953 261.613 1.00 73.56  ? 305 LYS C CG  1 
ATOM   404  C CD  . LYS A 1 48  ? 238.929 262.628 262.104 1.00 77.84  ? 305 LYS C CD  1 
ATOM   405  C CE  . LYS A 1 48  ? 238.960 261.289 262.820 1.00 75.88  ? 305 LYS C CE  1 
ATOM   406  N NZ  . LYS A 1 48  ? 239.902 261.296 263.970 1.00 74.06  ? 305 LYS C NZ  1 
ATOM   407  N N   . ALA A 1 49  ? 234.562 261.138 258.350 1.00 67.50  ? 306 ALA C N   1 
ATOM   408  C CA  . ALA A 1 49  ? 234.319 260.131 257.323 1.00 72.39  ? 306 ALA C CA  1 
ATOM   409  C C   . ALA A 1 49  ? 233.178 260.514 256.385 1.00 74.76  ? 306 ALA C C   1 
ATOM   410  O O   . ALA A 1 49  ? 233.352 260.537 255.163 1.00 80.86  ? 306 ALA C O   1 
ATOM   411  C CB  . ALA A 1 49  ? 234.034 258.777 257.981 1.00 72.88  ? 306 ALA C CB  1 
ATOM   412  N N   . LEU A 1 50  ? 232.006 260.813 256.941 1.00 62.04  ? 307 LEU C N   1 
ATOM   413  C CA  . LEU A 1 50  ? 230.804 260.984 256.135 1.00 65.72  ? 307 LEU C CA  1 
ATOM   414  C C   . LEU A 1 50  ? 230.578 262.419 255.671 1.00 66.00  ? 307 LEU C C   1 
ATOM   415  O O   . LEU A 1 50  ? 229.635 262.662 254.911 1.00 56.35  ? 307 LEU C O   1 
ATOM   416  C CB  . LEU A 1 50  ? 229.585 260.504 256.929 1.00 57.84  ? 307 LEU C CB  1 
ATOM   417  C CG  . LEU A 1 50  ? 228.307 260.140 256.169 1.00 61.49  ? 307 LEU C CG  1 
ATOM   418  C CD1 . LEU A 1 50  ? 228.615 259.197 255.020 1.00 65.44  ? 307 LEU C CD1 1 
ATOM   419  C CD2 . LEU A 1 50  ? 227.276 259.536 257.105 1.00 58.49  ? 307 LEU C CD2 1 
ATOM   420  N N   . PHE A 1 51  ? 231.417 263.371 256.080 1.00 67.63  ? 308 PHE C N   1 
ATOM   421  C CA  . PHE A 1 51  ? 231.080 264.777 255.926 1.00 61.49  ? 308 PHE C CA  1 
ATOM   422  C C   . PHE A 1 51  ? 232.101 265.613 255.169 1.00 64.44  ? 308 PHE C C   1 
ATOM   423  O O   . PHE A 1 51  ? 231.946 266.838 255.130 1.00 71.67  ? 308 PHE C O   1 
ATOM   424  C CB  . PHE A 1 51  ? 230.844 265.410 257.303 1.00 60.19  ? 308 PHE C CB  1 
ATOM   425  C CG  . PHE A 1 51  ? 229.452 265.219 257.816 1.00 60.52  ? 308 PHE C CG  1 
ATOM   426  C CD1 . PHE A 1 51  ? 228.385 265.144 256.941 1.00 61.39  ? 308 PHE C CD1 1 
ATOM   427  C CD2 . PHE A 1 51  ? 229.212 265.088 259.169 1.00 69.31  ? 308 PHE C CD2 1 
ATOM   428  C CE1 . PHE A 1 51  ? 227.104 264.962 257.410 1.00 65.44  ? 308 PHE C CE1 1 
ATOM   429  C CE2 . PHE A 1 51  ? 227.930 264.907 259.644 1.00 74.05  ? 308 PHE C CE2 1 
ATOM   430  C CZ  . PHE A 1 51  ? 226.875 264.844 258.762 1.00 71.53  ? 308 PHE C CZ  1 
ATOM   431  N N   . LYS A 1 52  ? 233.127 265.005 254.569 1.00 66.66  ? 309 LYS C N   1 
ATOM   432  C CA  . LYS A 1 52  ? 234.036 265.694 253.654 1.00 65.88  ? 309 LYS C CA  1 
ATOM   433  C C   . LYS A 1 52  ? 234.593 266.983 254.247 1.00 61.06  ? 309 LYS C C   1 
ATOM   434  O O   . LYS A 1 52  ? 234.158 268.073 253.856 1.00 59.87  ? 309 LYS C O   1 
ATOM   435  C CB  . LYS A 1 52  ? 233.328 265.998 252.332 1.00 61.18  ? 309 LYS C CB  1 
ATOM   436  N N   . PRO A 1 53  ? 235.513 266.894 255.220 1.00 65.66  ? 310 PRO C N   1 
ATOM   437  C CA  . PRO A 1 53  ? 236.123 268.074 255.826 1.00 60.82  ? 310 PRO C CA  1 
ATOM   438  C C   . PRO A 1 53  ? 236.327 269.263 254.900 1.00 58.81  ? 310 PRO C C   1 
ATOM   439  O O   . PRO A 1 53  ? 236.912 269.127 253.822 1.00 68.73  ? 310 PRO C O   1 
ATOM   440  C CB  . PRO A 1 53  ? 237.471 267.480 256.267 1.00 61.92  ? 310 PRO C CB  1 
ATOM   441  C CG  . PRO A 1 53  ? 236.997 265.909 256.511 1.00 73.11  ? 310 PRO C CG  1 
ATOM   442  C CD  . PRO A 1 53  ? 235.527 266.086 256.450 1.00 69.35  ? 310 PRO C CD  1 
ATOM   443  N N   . ALA A 1 54  ? 235.845 270.433 255.313 1.00 52.56  ? 311 ALA C N   1 
ATOM   444  C CA  . ALA A 1 54  ? 235.900 271.638 254.495 1.00 60.59  ? 311 ALA C CA  1 
ATOM   445  C C   . ALA A 1 54  ? 236.457 272.778 255.330 1.00 58.71  ? 311 ALA C C   1 
ATOM   446  O O   . ALA A 1 54  ? 236.074 272.948 256.491 1.00 62.51  ? 311 ALA C O   1 
ATOM   447  C CB  . ALA A 1 54  ? 234.516 272.000 253.950 1.00 63.76  ? 311 ALA C CB  1 
ATOM   448  N N   . ASP A 1 55  ? 237.359 273.554 254.738 1.00 76.05  ? 312 ASP C N   1 
ATOM   449  C CA  . ASP A 1 55  ? 237.957 274.703 255.402 1.00 78.63  ? 312 ASP C CA  1 
ATOM   450  C C   . ASP A 1 55  ? 237.245 275.974 254.964 1.00 73.77  ? 312 ASP C C   1 
ATOM   451  O O   . ASP A 1 55  ? 236.929 276.140 253.782 1.00 71.64  ? 312 ASP C O   1 
ATOM   452  C CB  . ASP A 1 55  ? 239.449 274.793 255.082 1.00 84.14  ? 312 ASP C CB  1 
ATOM   453  C CG  . ASP A 1 55  ? 240.032 276.159 255.392 1.00 83.23  ? 312 ASP C CG  1 
ATOM   454  O OD1 . ASP A 1 55  ? 239.758 276.691 256.489 1.00 82.03  ? 312 ASP C OD1 1 
ATOM   455  O OD2 . ASP A 1 55  ? 240.763 276.701 254.538 1.00 83.39  ? 312 ASP C OD2 1 
ATOM   456  N N   . VAL A 1 56  ? 237.000 276.867 255.915 1.00 62.97  ? 313 VAL C N   1 
ATOM   457  C CA  . VAL A 1 56  ? 236.328 278.133 255.656 1.00 60.36  ? 313 VAL C CA  1 
ATOM   458  C C   . VAL A 1 56  ? 237.304 279.251 255.987 1.00 61.72  ? 313 VAL C C   1 
ATOM   459  O O   . VAL A 1 56  ? 237.821 279.329 257.107 1.00 67.48  ? 313 VAL C O   1 
ATOM   460  C CB  . VAL A 1 56  ? 235.031 278.267 256.464 1.00 64.07  ? 313 VAL C CB  1 
ATOM   461  C CG1 . VAL A 1 56  ? 234.514 279.691 256.398 1.00 63.09  ? 313 VAL C CG1 1 
ATOM   462  C CG2 . VAL A 1 56  ? 233.988 277.294 255.946 1.00 66.25  ? 313 VAL C CG2 1 
ATOM   463  N N   . ILE A 1 57  ? 237.560 280.110 255.017 1.00 56.97  ? 314 ILE C N   1 
ATOM   464  C CA  . ILE A 1 57  ? 238.403 281.282 255.209 1.00 58.23  ? 314 ILE C CA  1 
ATOM   465  C C   . ILE A 1 57  ? 237.519 282.520 255.210 1.00 63.11  ? 314 ILE C C   1 
ATOM   466  O O   . ILE A 1 57  ? 236.604 282.663 254.392 1.00 56.75  ? 314 ILE C O   1 
ATOM   467  C CB  . ILE A 1 57  ? 239.518 281.345 254.140 1.00 62.62  ? 314 ILE C CB  1 
ATOM   468  C CG1 . ILE A 1 57  ? 238.971 281.693 252.748 1.00 59.34  ? 314 ILE C CG1 1 
ATOM   469  C CG2 . ILE A 1 57  ? 240.281 280.030 254.093 1.00 63.21  ? 314 ILE C CG2 1 
ATOM   470  C CD1 . ILE A 1 57  ? 239.050 283.166 252.383 1.00 56.71  ? 314 ILE C CD1 1 
ATOM   471  N N   . LEU A 1 58  ? 237.767 283.410 256.166 1.00 64.02  ? 315 LEU C N   1 
ATOM   472  C CA  . LEU A 1 58  ? 236.961 284.610 256.322 1.00 55.24  ? 315 LEU C CA  1 
ATOM   473  C C   . LEU A 1 58  ? 237.260 285.600 255.206 1.00 54.22  ? 315 LEU C C   1 
ATOM   474  O O   . LEU A 1 58  ? 238.412 285.775 254.804 1.00 49.97  ? 315 LEU C O   1 
ATOM   475  C CB  . LEU A 1 58  ? 237.210 285.257 257.683 1.00 52.53  ? 315 LEU C CB  1 
ATOM   476  C CG  . LEU A 1 58  ? 236.529 284.539 258.847 1.00 53.91  ? 315 LEU C CG  1 
ATOM   477  C CD1 . LEU A 1 58  ? 236.776 285.270 260.154 1.00 61.16  ? 315 LEU C CD1 1 
ATOM   478  C CD2 . LEU A 1 58  ? 235.043 284.407 258.575 1.00 52.68  ? 315 LEU C CD2 1 
ATOM   479  N N   . ASP A 1 59  ? 236.210 286.245 254.713 1.00 56.28  ? 316 ASP C N   1 
ATOM   480  C CA  . ASP A 1 59  ? 236.320 287.172 253.595 1.00 52.66  ? 316 ASP C CA  1 
ATOM   481  C C   . ASP A 1 59  ? 236.216 288.601 254.106 1.00 59.62  ? 316 ASP C C   1 
ATOM   482  O O   . ASP A 1 59  ? 235.138 289.011 254.565 1.00 58.48  ? 316 ASP C O   1 
ATOM   483  C CB  . ASP A 1 59  ? 235.230 286.887 252.563 1.00 54.57  ? 316 ASP C CB  1 
ATOM   484  C CG  . ASP A 1 59  ? 234.899 288.091 251.719 1.00 58.47  ? 316 ASP C CG  1 
ATOM   485  O OD1 . ASP A 1 59  ? 235.675 288.397 250.790 1.00 62.64  ? 316 ASP C OD1 1 
ATOM   486  O OD2 . ASP A 1 59  ? 233.861 288.729 251.981 1.00 57.67  ? 316 ASP C OD2 1 
ATOM   487  N N   . PRO A 1 60  ? 237.294 289.386 254.067 1.00 68.51  ? 317 PRO C N   1 
ATOM   488  C CA  . PRO A 1 60  ? 237.208 290.770 254.559 1.00 61.85  ? 317 PRO C CA  1 
ATOM   489  C C   . PRO A 1 60  ? 236.269 291.637 253.747 1.00 55.69  ? 317 PRO C C   1 
ATOM   490  O O   . PRO A 1 60  ? 235.809 292.674 254.239 1.00 56.40  ? 317 PRO C O   1 
ATOM   491  C CB  . PRO A 1 60  ? 238.657 291.270 254.456 1.00 58.31  ? 317 PRO C CB  1 
ATOM   492  C CG  . PRO A 1 60  ? 239.494 290.038 254.355 1.00 62.16  ? 317 PRO C CG  1 
ATOM   493  C CD  . PRO A 1 60  ? 238.653 289.046 253.620 1.00 64.81  ? 317 PRO C CD  1 
ATOM   494  N N   . LYS A 1 61  ? 235.966 291.236 252.515 1.00 56.44  ? 318 LYS C N   1 
ATOM   495  C CA  . LYS A 1 61  ? 235.294 292.127 251.583 1.00 53.07  ? 318 LYS C CA  1 
ATOM   496  C C   . LYS A 1 61  ? 233.816 292.286 251.916 1.00 53.95  ? 318 LYS C C   1 
ATOM   497  O O   . LYS A 1 61  ? 233.189 293.253 251.471 1.00 56.59  ? 318 LYS C O   1 
ATOM   498  C CB  . LYS A 1 61  ? 235.480 291.591 250.163 1.00 50.14  ? 318 LYS C CB  1 
ATOM   499  C CG  . LYS A 1 61  ? 234.942 292.473 249.076 1.00 46.92  ? 318 LYS C CG  1 
ATOM   500  C CD  . LYS A 1 61  ? 235.858 293.673 248.950 1.00 52.69  ? 318 LYS C CD  1 
ATOM   501  C CE  . LYS A 1 61  ? 235.266 294.747 248.074 1.00 61.45  ? 318 LYS C CE  1 
ATOM   502  N NZ  . LYS A 1 61  ? 235.588 296.107 248.589 1.00 57.55  ? 318 LYS C NZ  1 
ATOM   503  N N   . THR A 1 62  ? 233.252 291.371 252.703 1.00 51.54  ? 319 THR C N   1 
ATOM   504  C CA  . THR A 1 62  ? 231.865 291.450 253.139 1.00 54.70  ? 319 THR C CA  1 
ATOM   505  C C   . THR A 1 62  ? 231.715 291.883 254.591 1.00 52.67  ? 319 THR C C   1 
ATOM   506  O O   . THR A 1 62  ? 230.593 292.157 255.024 1.00 52.78  ? 319 THR C O   1 
ATOM   507  C CB  . THR A 1 62  ? 231.172 290.097 252.947 1.00 61.13  ? 319 THR C CB  1 
ATOM   508  O OG1 . THR A 1 62  ? 232.019 289.053 253.441 1.00 55.31  ? 319 THR C OG1 1 
ATOM   509  C CG2 . THR A 1 62  ? 230.881 289.850 251.479 1.00 61.17  ? 319 THR C CG2 1 
ATOM   510  N N   . ALA A 1 63  ? 232.808 291.948 255.344 1.00 53.23  ? 320 ALA C N   1 
ATOM   511  C CA  . ALA A 1 63  ? 232.731 292.283 256.757 1.00 53.32  ? 320 ALA C CA  1 
ATOM   512  C C   . ALA A 1 63  ? 232.258 293.717 256.958 1.00 46.88  ? 320 ALA C C   1 
ATOM   513  O O   . ALA A 1 63  ? 232.482 294.594 256.121 1.00 57.39  ? 320 ALA C O   1 
ATOM   514  C CB  . ALA A 1 63  ? 234.090 292.090 257.427 1.00 54.84  ? 320 ALA C CB  1 
ATOM   515  N N   . ASN A 1 64  ? 231.590 293.944 258.085 1.00 55.18  ? 321 ASN C N   1 
ATOM   516  C CA  . ASN A 1 64  ? 231.193 295.286 258.466 1.00 64.74  ? 321 ASN C CA  1 
ATOM   517  C C   . ASN A 1 64  ? 232.432 296.124 258.770 1.00 63.85  ? 321 ASN C C   1 
ATOM   518  O O   . ASN A 1 64  ? 233.490 295.586 259.105 1.00 63.68  ? 321 ASN C O   1 
ATOM   519  C CB  . ASN A 1 64  ? 230.275 295.241 259.685 1.00 60.06  ? 321 ASN C CB  1 
ATOM   520  C CG  . ASN A 1 64  ? 229.108 296.199 259.572 1.00 51.13  ? 321 ASN C CG  1 
ATOM   521  O OD1 . ASN A 1 64  ? 228.440 296.257 258.543 1.00 55.93  ? 321 ASN C OD1 1 
ATOM   522  N ND2 . ASN A 1 64  ? 228.863 296.963 260.629 1.00 43.38  ? 321 ASN C ND2 1 
ATOM   523  N N   . PRO A 1 65  ? 232.331 297.450 258.644 1.00 57.68  ? 322 PRO C N   1 
ATOM   524  C CA  . PRO A 1 65  ? 233.472 298.298 259.021 1.00 52.62  ? 322 PRO C CA  1 
ATOM   525  C C   . PRO A 1 65  ? 233.873 298.148 260.476 1.00 55.70  ? 322 PRO C C   1 
ATOM   526  O O   . PRO A 1 65  ? 235.033 298.402 260.819 1.00 57.94  ? 322 PRO C O   1 
ATOM   527  C CB  . PRO A 1 65  ? 232.971 299.716 258.714 1.00 58.36  ? 322 PRO C CB  1 
ATOM   528  C CG  . PRO A 1 65  ? 231.892 299.530 257.709 1.00 53.90  ? 322 PRO C CG  1 
ATOM   529  C CD  . PRO A 1 65  ? 231.235 298.232 258.049 1.00 50.67  ? 322 PRO C CD  1 
ATOM   530  N N   . ILE A 1 66  ? 232.946 297.740 261.347 1.00 55.35  ? 323 ILE C N   1 
ATOM   531  C CA  . ILE A 1 66  ? 233.270 297.576 262.757 1.00 51.95  ? 323 ILE C CA  1 
ATOM   532  C C   . ILE A 1 66  ? 234.077 296.310 263.019 1.00 52.92  ? 323 ILE C C   1 
ATOM   533  O O   . ILE A 1 66  ? 234.777 296.229 264.034 1.00 58.53  ? 323 ILE C O   1 
ATOM   534  C CB  . ILE A 1 66  ? 231.984 297.579 263.602 1.00 55.39  ? 323 ILE C CB  1 
ATOM   535  C CG1 . ILE A 1 66  ? 232.226 298.254 264.950 1.00 56.24  ? 323 ILE C CG1 1 
ATOM   536  C CG2 . ILE A 1 66  ? 231.488 296.169 263.813 1.00 60.63  ? 323 ILE C CG2 1 
ATOM   537  C CD1 . ILE A 1 66  ? 232.747 299.653 264.842 1.00 58.64  ? 323 ILE C CD1 1 
ATOM   538  N N   . LEU A 1 67  ? 234.006 295.319 262.135 1.00 50.08  ? 324 LEU C N   1 
ATOM   539  C CA  . LEU A 1 67  ? 234.690 294.051 262.345 1.00 53.14  ? 324 LEU C CA  1 
ATOM   540  C C   . LEU A 1 67  ? 236.082 294.102 261.733 1.00 51.88  ? 324 LEU C C   1 
ATOM   541  O O   . LEU A 1 67  ? 236.249 294.545 260.592 1.00 59.66  ? 324 LEU C O   1 
ATOM   542  C CB  . LEU A 1 67  ? 233.893 292.898 261.737 1.00 55.51  ? 324 LEU C CB  1 
ATOM   543  C CG  . LEU A 1 67  ? 232.405 292.826 262.067 1.00 50.31  ? 324 LEU C CG  1 
ATOM   544  C CD1 . LEU A 1 67  ? 231.694 291.887 261.112 1.00 47.97  ? 324 LEU C CD1 1 
ATOM   545  C CD2 . LEU A 1 67  ? 232.202 292.383 263.502 1.00 52.38  ? 324 LEU C CD2 1 
ATOM   546  N N   . LEU A 1 68  ? 237.077 293.651 262.489 1.00 46.21  ? 325 LEU C N   1 
ATOM   547  C CA  . LEU A 1 68  ? 238.450 293.572 262.012 1.00 51.34  ? 325 LEU C CA  1 
ATOM   548  C C   . LEU A 1 68  ? 238.789 292.114 261.729 1.00 56.17  ? 325 LEU C C   1 
ATOM   549  O O   . LEU A 1 68  ? 238.937 291.315 262.659 1.00 62.63  ? 325 LEU C O   1 
ATOM   550  C CB  . LEU A 1 68  ? 239.416 294.162 263.040 1.00 49.84  ? 325 LEU C CB  1 
ATOM   551  C CG  . LEU A 1 68  ? 240.910 294.081 262.724 1.00 54.96  ? 325 LEU C CG  1 
ATOM   552  C CD1 . LEU A 1 68  ? 241.329 295.211 261.802 1.00 55.25  ? 325 LEU C CD1 1 
ATOM   553  C CD2 . LEU A 1 68  ? 241.728 294.103 264.000 1.00 54.28  ? 325 LEU C CD2 1 
ATOM   554  N N   . VAL A 1 69  ? 238.895 291.765 260.456 1.00 57.13  ? 326 VAL C N   1 
ATOM   555  C CA  . VAL A 1 69  ? 239.321 290.429 260.062 1.00 54.15  ? 326 VAL C CA  1 
ATOM   556  C C   . VAL A 1 69  ? 240.823 290.333 260.277 1.00 56.82  ? 326 VAL C C   1 
ATOM   557  O O   . VAL A 1 69  ? 241.588 291.155 259.757 1.00 64.32  ? 326 VAL C O   1 
ATOM   558  C CB  . VAL A 1 69  ? 238.946 290.133 258.602 1.00 58.88  ? 326 VAL C CB  1 
ATOM   559  C CG1 . VAL A 1 69  ? 239.492 288.783 258.182 1.00 57.16  ? 326 VAL C CG1 1 
ATOM   560  C CG2 . VAL A 1 69  ? 237.440 290.171 258.430 1.00 58.23  ? 326 VAL C CG2 1 
ATOM   561  N N   . SER A 1 70  ? 241.248 289.338 261.047 1.00 59.56  ? 327 SER C N   1 
ATOM   562  C CA  . SER A 1 70  ? 242.648 289.233 261.418 1.00 66.85  ? 327 SER C CA  1 
ATOM   563  C C   . SER A 1 70  ? 243.510 288.931 260.195 1.00 66.91  ? 327 SER C C   1 
ATOM   564  O O   . SER A 1 70  ? 243.024 288.514 259.141 1.00 64.87  ? 327 SER C O   1 
ATOM   565  C CB  . SER A 1 70  ? 242.840 288.155 262.484 1.00 67.12  ? 327 SER C CB  1 
ATOM   566  O OG  . SER A 1 70  ? 243.999 288.408 263.257 1.00 65.16  ? 327 SER C OG  1 
ATOM   567  N N   . GLU A 1 71  ? 244.817 289.155 260.353 1.00 85.31  ? 328 GLU C N   1 
ATOM   568  C CA  . GLU A 1 71  ? 245.738 289.029 259.228 1.00 86.15  ? 328 GLU C CA  1 
ATOM   569  C C   . GLU A 1 71  ? 245.772 287.603 258.694 1.00 84.38  ? 328 GLU C C   1 
ATOM   570  O O   . GLU A 1 71  ? 245.996 287.386 257.498 1.00 87.57  ? 328 GLU C O   1 
ATOM   571  C CB  . GLU A 1 71  ? 247.136 289.486 259.649 1.00 88.58  ? 328 GLU C CB  1 
ATOM   572  C CG  . GLU A 1 71  ? 248.161 289.524 258.526 1.00 87.18  ? 328 GLU C CG  1 
ATOM   573  C CD  . GLU A 1 71  ? 248.941 288.232 258.397 1.00 92.71  ? 328 GLU C CD  1 
ATOM   574  O OE1 . GLU A 1 71  ? 248.751 287.333 259.243 1.00 92.76  ? 328 GLU C OE1 1 
ATOM   575  O OE2 . GLU A 1 71  ? 249.746 288.115 257.450 1.00 93.68  ? 328 GLU C OE2 1 
ATOM   576  N N   . ASP A 1 72  ? 245.548 286.618 259.561 1.00 69.99  ? 329 ASP C N   1 
ATOM   577  C CA  . ASP A 1 72  ? 245.545 285.225 259.133 1.00 73.03  ? 329 ASP C CA  1 
ATOM   578  C C   . ASP A 1 72  ? 244.295 284.830 258.352 1.00 76.81  ? 329 ASP C C   1 
ATOM   579  O O   . ASP A 1 72  ? 244.185 283.665 257.954 1.00 78.13  ? 329 ASP C O   1 
ATOM   580  C CB  . ASP A 1 72  ? 245.798 284.320 260.357 1.00 80.57  ? 329 ASP C CB  1 
ATOM   581  C CG  . ASP A 1 72  ? 244.522 283.872 261.094 1.00 84.31  ? 329 ASP C CG  1 
ATOM   582  O OD1 . ASP A 1 72  ? 243.381 284.203 260.716 1.00 86.46  ? 329 ASP C OD1 1 
ATOM   583  O OD2 . ASP A 1 72  ? 244.685 283.223 262.148 1.00 81.91  ? 329 ASP C OD2 1 
ATOM   584  N N   . GLN A 1 73  ? 243.358 285.754 258.142 1.00 66.15  ? 330 GLN C N   1 
ATOM   585  C CA  . GLN A 1 73  ? 242.160 285.561 257.328 1.00 62.82  ? 330 GLN C CA  1 
ATOM   586  C C   . GLN A 1 73  ? 241.227 284.489 257.875 1.00 69.90  ? 330 GLN C C   1 
ATOM   587  O O   . GLN A 1 73  ? 240.267 284.108 257.195 1.00 74.92  ? 330 GLN C O   1 
ATOM   588  C CB  . GLN A 1 73  ? 242.515 285.235 255.872 1.00 60.16  ? 330 GLN C CB  1 
ATOM   589  C CG  . GLN A 1 73  ? 243.214 286.359 255.135 1.00 66.10  ? 330 GLN C CG  1 
ATOM   590  C CD  . GLN A 1 73  ? 242.267 287.159 254.268 1.00 70.15  ? 330 GLN C CD  1 
ATOM   591  O OE1 . GLN A 1 73  ? 242.201 288.383 254.369 1.00 67.23  ? 330 GLN C OE1 1 
ATOM   592  N NE2 . GLN A 1 73  ? 241.523 286.471 253.413 1.00 73.84  ? 330 GLN C NE2 1 
ATOM   593  N N   . ARG A 1 74  ? 241.475 283.990 259.084 1.00 63.98  ? 331 ARG C N   1 
ATOM   594  C CA  . ARG A 1 74  ? 240.625 282.976 259.692 1.00 59.18  ? 331 ARG C CA  1 
ATOM   595  C C   . ARG A 1 74  ? 239.893 283.460 260.931 1.00 57.36  ? 331 ARG C C   1 
ATOM   596  O O   . ARG A 1 74  ? 238.823 282.935 261.242 1.00 62.68  ? 331 ARG C O   1 
ATOM   597  C CB  . ARG A 1 74  ? 241.453 281.740 260.061 1.00 61.22  ? 331 ARG C CB  1 
ATOM   598  C CG  . ARG A 1 74  ? 242.247 281.161 258.908 1.00 57.72  ? 331 ARG C CG  1 
ATOM   599  C CD  . ARG A 1 74  ? 241.540 279.966 258.302 1.00 58.01  ? 331 ARG C CD  1 
ATOM   600  N NE  . ARG A 1 74  ? 242.345 279.323 257.272 1.00 59.60  ? 331 ARG C NE  1 
ATOM   601  C CZ  . ARG A 1 74  ? 243.305 278.443 257.516 1.00 62.64  ? 331 ARG C CZ  1 
ATOM   602  N NH1 . ARG A 1 74  ? 243.614 278.081 258.749 1.00 62.16  ? 331 ARG C NH1 1 
ATOM   603  N NH2 . ARG A 1 74  ? 243.974 277.914 256.496 1.00 64.56  ? 331 ARG C NH2 1 
ATOM   604  N N   . SER A 1 75  ? 240.439 284.439 261.641 1.00 55.79  ? 332 SER C N   1 
ATOM   605  C CA  . SER A 1 75  ? 239.844 284.951 262.865 1.00 59.83  ? 332 SER C CA  1 
ATOM   606  C C   . SER A 1 75  ? 239.180 286.298 262.612 1.00 63.20  ? 332 SER C C   1 
ATOM   607  O O   . SER A 1 75  ? 239.520 287.010 261.664 1.00 73.85  ? 332 SER C O   1 
ATOM   608  C CB  . SER A 1 75  ? 240.900 285.094 263.963 1.00 67.31  ? 332 SER C CB  1 
ATOM   609  O OG  . SER A 1 75  ? 241.841 284.037 263.906 1.00 71.36  ? 332 SER C OG  1 
ATOM   610  N N   . VAL A 1 76  ? 238.226 286.640 263.472 1.00 44.41  ? 333 VAL C N   1 
ATOM   611  C CA  . VAL A 1 76  ? 237.520 287.913 263.401 1.00 49.43  ? 333 VAL C CA  1 
ATOM   612  C C   . VAL A 1 76  ? 237.516 288.535 264.790 1.00 51.73  ? 333 VAL C C   1 
ATOM   613  O O   . VAL A 1 76  ? 237.279 287.842 265.785 1.00 58.29  ? 333 VAL C O   1 
ATOM   614  C CB  . VAL A 1 76  ? 236.086 287.743 262.858 1.00 47.61  ? 333 VAL C CB  1 
ATOM   615  C CG1 . VAL A 1 76  ? 235.331 286.687 263.640 1.00 51.96  ? 333 VAL C CG1 1 
ATOM   616  C CG2 . VAL A 1 76  ? 235.339 289.065 262.880 1.00 50.36  ? 333 VAL C CG2 1 
ATOM   617  N N   . GLN A 1 77  ? 237.799 289.832 264.861 1.00 52.25  ? 334 GLN C N   1 
ATOM   618  C CA  . GLN A 1 77  ? 237.814 290.578 266.106 1.00 49.07  ? 334 GLN C CA  1 
ATOM   619  C C   . GLN A 1 77  ? 236.851 291.754 266.018 1.00 50.76  ? 334 GLN C C   1 
ATOM   620  O O   . GLN A 1 77  ? 236.463 292.191 264.931 1.00 60.41  ? 334 GLN C O   1 
ATOM   621  C CB  . GLN A 1 77  ? 239.224 291.082 266.424 1.00 51.86  ? 334 GLN C CB  1 
ATOM   622  C CG  . GLN A 1 77  ? 240.065 290.112 267.221 1.00 55.01  ? 334 GLN C CG  1 
ATOM   623  C CD  . GLN A 1 77  ? 240.627 290.740 268.476 1.00 58.76  ? 334 GLN C CD  1 
ATOM   624  O OE1 . GLN A 1 77  ? 241.228 291.813 268.430 1.00 58.72  ? 334 GLN C OE1 1 
ATOM   625  N NE2 . GLN A 1 77  ? 240.433 290.076 269.608 1.00 61.00  ? 334 GLN C NE2 1 
ATOM   626  N N   . ARG A 1 78  ? 236.477 292.269 267.182 1.00 47.57  ? 335 ARG C N   1 
ATOM   627  C CA  . ARG A 1 78  ? 235.569 293.401 267.288 1.00 57.51  ? 335 ARG C CA  1 
ATOM   628  C C   . ARG A 1 78  ? 236.387 294.637 267.644 1.00 62.31  ? 335 ARG C C   1 
ATOM   629  O O   . ARG A 1 78  ? 237.119 294.635 268.639 1.00 65.69  ? 335 ARG C O   1 
ATOM   630  C CB  . ARG A 1 78  ? 234.499 293.126 268.349 1.00 57.38  ? 335 ARG C CB  1 
ATOM   631  C CG  . ARG A 1 78  ? 233.675 294.323 268.796 1.00 54.16  ? 335 ARG C CG  1 
ATOM   632  C CD  . ARG A 1 78  ? 233.232 295.190 267.635 1.00 52.71  ? 335 ARG C CD  1 
ATOM   633  N NE  . ARG A 1 78  ? 232.114 296.049 267.997 1.00 54.30  ? 335 ARG C NE  1 
ATOM   634  C CZ  . ARG A 1 78  ? 230.848 295.775 267.722 1.00 60.51  ? 335 ARG C CZ  1 
ATOM   635  N NH1 . ARG A 1 78  ? 230.502 294.649 267.124 1.00 63.88  ? 335 ARG C NH1 1 
ATOM   636  N NH2 . ARG A 1 78  ? 229.905 296.646 268.069 1.00 59.71  ? 335 ARG C NH2 1 
ATOM   637  N N   . ALA A 1 79  ? 236.261 295.685 266.835 1.00 64.28  ? 336 ALA C N   1 
ATOM   638  C CA  . ALA A 1 79  ? 237.006 296.923 266.997 1.00 56.82  ? 336 ALA C CA  1 
ATOM   639  C C   . ALA A 1 79  ? 236.131 297.976 267.674 1.00 59.22  ? 336 ALA C C   1 
ATOM   640  O O   . ALA A 1 79  ? 235.025 297.691 268.143 1.00 67.27  ? 336 ALA C O   1 
ATOM   641  C CB  . ALA A 1 79  ? 237.526 297.403 265.641 1.00 59.37  ? 336 ALA C CB  1 
ATOM   642  N N   . LYS A 1 80  ? 236.637 299.207 267.734 1.00 54.42  ? 337 LYS C N   1 
ATOM   643  C CA  . LYS A 1 80  ? 235.929 300.285 268.417 1.00 56.90  ? 337 LYS C CA  1 
ATOM   644  C C   . LYS A 1 80  ? 235.040 301.086 267.468 1.00 59.64  ? 337 LYS C C   1 
ATOM   645  O O   . LYS A 1 80  ? 233.827 301.180 267.675 1.00 62.40  ? 337 LYS C O   1 
ATOM   646  C CB  . LYS A 1 80  ? 236.935 301.208 269.116 1.00 62.61  ? 337 LYS C CB  1 
ATOM   647  C CG  . LYS A 1 80  ? 237.879 300.508 270.096 1.00 63.08  ? 337 LYS C CG  1 
ATOM   648  C CD  . LYS A 1 80  ? 237.180 299.748 271.233 1.00 66.65  ? 337 LYS C CD  1 
ATOM   649  C CE  . LYS A 1 80  ? 235.955 300.465 271.808 1.00 68.62  ? 337 LYS C CE  1 
ATOM   650  N NZ  . LYS A 1 80  ? 236.205 301.905 272.103 1.00 66.54  ? 337 LYS C NZ  1 
ATOM   651  N N   . GLU A 1 81  ? 235.628 301.663 266.423 1.00 69.75  ? 338 GLU C N   1 
ATOM   652  C CA  . GLU A 1 81  ? 234.894 302.558 265.546 1.00 69.69  ? 338 GLU C CA  1 
ATOM   653  C C   . GLU A 1 81  ? 235.000 302.100 264.096 1.00 67.84  ? 338 GLU C C   1 
ATOM   654  O O   . GLU A 1 81  ? 235.976 301.445 263.716 1.00 68.39  ? 338 GLU C O   1 
ATOM   655  C CB  . GLU A 1 81  ? 235.414 303.996 265.671 1.00 73.66  ? 338 GLU C CB  1 
ATOM   656  C CG  . GLU A 1 81  ? 236.660 304.288 264.854 1.00 75.82  ? 338 GLU C CG  1 
ATOM   657  C CD  . GLU A 1 81  ? 237.886 303.577 265.388 1.00 78.67  ? 338 GLU C CD  1 
ATOM   658  O OE1 . GLU A 1 81  ? 237.913 303.262 266.596 1.00 79.86  ? 338 GLU C OE1 1 
ATOM   659  O OE2 . GLU A 1 81  ? 238.822 303.331 264.599 1.00 75.59  ? 338 GLU C OE2 1 
ATOM   660  N N   . PRO A 1 82  ? 234.005 302.414 263.266 1.00 63.43  ? 339 PRO C N   1 
ATOM   661  C CA  . PRO A 1 82  ? 234.030 301.961 261.866 1.00 65.56  ? 339 PRO C CA  1 
ATOM   662  C C   . PRO A 1 82  ? 235.043 302.752 261.053 1.00 71.19  ? 339 PRO C C   1 
ATOM   663  O O   . PRO A 1 82  ? 234.909 303.966 260.885 1.00 78.04  ? 339 PRO C O   1 
ATOM   664  C CB  . PRO A 1 82  ? 232.596 302.216 261.382 1.00 62.82  ? 339 PRO C CB  1 
ATOM   665  C CG  . PRO A 1 82  ? 231.791 302.501 262.614 1.00 63.55  ? 339 PRO C CG  1 
ATOM   666  C CD  . PRO A 1 82  ? 232.742 303.091 263.597 1.00 67.03  ? 339 PRO C CD  1 
ATOM   667  N N   . GLN A 1 83  ? 236.060 302.061 260.548 1.00 66.57  ? 340 GLN C N   1 
ATOM   668  C CA  . GLN A 1 83  ? 237.005 302.685 259.636 1.00 65.97  ? 340 GLN C CA  1 
ATOM   669  C C   . GLN A 1 83  ? 236.394 302.802 258.244 1.00 65.86  ? 340 GLN C C   1 
ATOM   670  O O   . GLN A 1 83  ? 235.643 301.932 257.795 1.00 68.95  ? 340 GLN C O   1 
ATOM   671  C CB  . GLN A 1 83  ? 238.313 301.893 259.581 1.00 65.69  ? 340 GLN C CB  1 
ATOM   672  C CG  . GLN A 1 83  ? 238.210 300.543 258.894 1.00 65.58  ? 340 GLN C CG  1 
ATOM   673  C CD  . GLN A 1 83  ? 237.612 299.483 259.790 1.00 63.60  ? 340 GLN C CD  1 
ATOM   674  O OE1 . GLN A 1 83  ? 237.827 299.486 261.001 1.00 63.79  ? 340 GLN C OE1 1 
ATOM   675  N NE2 . GLN A 1 83  ? 236.850 298.570 259.201 1.00 61.12  ? 340 GLN C NE2 1 
ATOM   676  N N   . ASP A 1 84  ? 236.708 303.902 257.568 1.00 67.90  ? 341 ASP C N   1 
ATOM   677  C CA  . ASP A 1 84  ? 236.121 304.184 256.266 1.00 69.12  ? 341 ASP C CA  1 
ATOM   678  C C   . ASP A 1 84  ? 236.714 303.265 255.208 1.00 68.90  ? 341 ASP C C   1 
ATOM   679  O O   . ASP A 1 84  ? 237.930 303.054 255.168 1.00 75.81  ? 341 ASP C O   1 
ATOM   680  C CB  . ASP A 1 84  ? 236.349 305.646 255.885 1.00 73.20  ? 341 ASP C CB  1 
ATOM   681  C CG  . ASP A 1 84  ? 235.354 306.143 254.854 1.00 79.17  ? 341 ASP C CG  1 
ATOM   682  O OD1 . ASP A 1 84  ? 234.906 305.334 254.014 1.00 80.99  ? 341 ASP C OD1 1 
ATOM   683  O OD2 . ASP A 1 84  ? 235.019 307.346 254.883 1.00 81.03  ? 341 ASP C OD2 1 
ATOM   684  N N   . LEU A 1 85  ? 235.856 302.731 254.348 1.00 54.72  ? 342 LEU C N   1 
ATOM   685  C CA  . LEU A 1 85  ? 236.265 301.852 253.262 1.00 56.92  ? 342 LEU C CA  1 
ATOM   686  C C   . LEU A 1 85  ? 235.052 301.619 252.358 1.00 56.66  ? 342 LEU C C   1 
ATOM   687  O O   . LEU A 1 85  ? 233.913 301.711 252.823 1.00 60.83  ? 342 LEU C O   1 
ATOM   688  C CB  . LEU A 1 85  ? 236.835 300.529 253.803 1.00 63.03  ? 342 LEU C CB  1 
ATOM   689  C CG  . LEU A 1 85  ? 235.953 299.361 254.225 1.00 63.61  ? 342 LEU C CG  1 
ATOM   690  C CD1 . LEU A 1 85  ? 236.815 298.114 254.221 1.00 55.41  ? 342 LEU C CD1 1 
ATOM   691  C CD2 . LEU A 1 85  ? 235.341 299.595 255.591 1.00 61.58  ? 342 LEU C CD2 1 
ATOM   692  N N   . PRO A 1 86  ? 235.271 301.325 251.075 1.00 50.03  ? 343 PRO C N   1 
ATOM   693  C CA  . PRO A 1 86  ? 234.181 301.437 250.095 1.00 53.13  ? 343 PRO C CA  1 
ATOM   694  C C   . PRO A 1 86  ? 233.025 300.490 250.379 1.00 53.13  ? 343 PRO C C   1 
ATOM   695  O O   . PRO A 1 86  ? 233.184 299.405 250.942 1.00 56.88  ? 343 PRO C O   1 
ATOM   696  C CB  . PRO A 1 86  ? 234.844 301.104 248.753 1.00 53.43  ? 343 PRO C CB  1 
ATOM   697  C CG  . PRO A 1 86  ? 236.221 300.680 249.040 1.00 53.89  ? 343 PRO C CG  1 
ATOM   698  C CD  . PRO A 1 86  ? 236.500 300.753 250.496 1.00 54.16  ? 343 PRO C CD  1 
ATOM   699  N N   . ASP A 1 87  ? 231.838 300.933 249.968 1.00 51.30  ? 344 ASP C N   1 
ATOM   700  C CA  . ASP A 1 87  ? 230.577 300.243 250.240 1.00 51.30  ? 344 ASP C CA  1 
ATOM   701  C C   . ASP A 1 87  ? 230.156 299.473 248.994 1.00 52.81  ? 344 ASP C C   1 
ATOM   702  O O   . ASP A 1 87  ? 229.366 299.953 248.181 1.00 52.30  ? 344 ASP C O   1 
ATOM   703  C CB  . ASP A 1 87  ? 229.506 301.242 250.663 1.00 52.53  ? 344 ASP C CB  1 
ATOM   704  C CG  . ASP A 1 87  ? 228.205 300.573 251.061 1.00 56.52  ? 344 ASP C CG  1 
ATOM   705  O OD1 . ASP A 1 87  ? 228.166 299.329 251.144 1.00 57.02  ? 344 ASP C OD1 1 
ATOM   706  O OD2 . ASP A 1 87  ? 227.214 301.297 251.285 1.00 60.53  ? 344 ASP C OD2 1 
ATOM   707  N N   . ASN A 1 88  ? 230.682 298.266 248.850 1.00 53.59  ? 345 ASN C N   1 
ATOM   708  C CA  . ASN A 1 88  ? 230.254 297.382 247.782 1.00 48.78  ? 345 ASN C CA  1 
ATOM   709  C C   . ASN A 1 88  ? 228.942 296.700 248.150 1.00 53.06  ? 345 ASN C C   1 
ATOM   710  O O   . ASN A 1 88  ? 228.597 296.595 249.329 1.00 62.92  ? 345 ASN C O   1 
ATOM   711  C CB  . ASN A 1 88  ? 231.334 296.348 247.501 1.00 45.85  ? 345 ASN C CB  1 
ATOM   712  C CG  . ASN A 1 88  ? 232.722 296.905 247.685 1.00 53.16  ? 345 ASN C CG  1 
ATOM   713  O OD1 . ASN A 1 88  ? 233.087 297.350 248.772 1.00 50.07  ? 345 ASN C OD1 1 
ATOM   714  N ND2 . ASN A 1 88  ? 233.497 296.922 246.608 1.00 57.31  ? 345 ASN C ND2 1 
ATOM   715  N N   . PRO A 1 89  ? 228.181 296.237 247.155 1.00 52.54  ? 346 PRO C N   1 
ATOM   716  C CA  . PRO A 1 89  ? 226.941 295.507 247.468 1.00 54.80  ? 346 PRO C CA  1 
ATOM   717  C C   . PRO A 1 89  ? 227.174 294.256 248.295 1.00 67.09  ? 346 PRO C C   1 
ATOM   718  O O   . PRO A 1 89  ? 226.273 293.842 249.034 1.00 67.28  ? 346 PRO C O   1 
ATOM   719  C CB  . PRO A 1 89  ? 226.369 295.170 246.084 1.00 48.17  ? 346 PRO C CB  1 
ATOM   720  C CG  . PRO A 1 89  ? 226.987 296.166 245.167 1.00 54.12  ? 346 PRO C CG  1 
ATOM   721  C CD  . PRO A 1 89  ? 228.359 296.418 245.705 1.00 53.15  ? 346 PRO C CD  1 
ATOM   722  N N   . GLU A 1 90  ? 228.353 293.638 248.191 1.00 66.46  ? 347 GLU C N   1 
ATOM   723  C CA  . GLU A 1 90  ? 228.681 292.518 249.065 1.00 54.19  ? 347 GLU C CA  1 
ATOM   724  C C   . GLU A 1 90  ? 228.766 292.948 250.521 1.00 46.52  ? 347 GLU C C   1 
ATOM   725  O O   . GLU A 1 90  ? 228.320 292.215 251.410 1.00 45.55  ? 347 GLU C O   1 
ATOM   726  C CB  . GLU A 1 90  ? 230.003 291.884 248.639 1.00 49.09  ? 347 GLU C CB  1 
ATOM   727  C CG  . GLU A 1 90  ? 230.099 291.537 247.171 1.00 56.36  ? 347 GLU C CG  1 
ATOM   728  C CD  . GLU A 1 90  ? 231.390 290.821 246.837 1.00 61.31  ? 347 GLU C CD  1 
ATOM   729  O OE1 . GLU A 1 90  ? 232.390 291.041 247.549 1.00 60.01  ? 347 GLU C OE1 1 
ATOM   730  O OE2 . GLU A 1 90  ? 231.405 290.036 245.868 1.00 66.30  ? 347 GLU C OE2 1 
ATOM   731  N N   . ARG A 1 91  ? 229.337 294.120 250.782 1.00 50.06  ? 348 ARG C N   1 
ATOM   732  C CA  . ARG A 1 91  ? 229.650 294.556 252.135 1.00 50.78  ? 348 ARG C CA  1 
ATOM   733  C C   . ARG A 1 91  ? 228.383 294.848 252.926 1.00 46.49  ? 348 ARG C C   1 
ATOM   734  O O   . ARG A 1 91  ? 227.449 295.471 252.413 1.00 34.17  ? 348 ARG C O   1 
ATOM   735  C CB  . ARG A 1 91  ? 230.539 295.797 252.101 1.00 50.10  ? 348 ARG C CB  1 
ATOM   736  C CG  . ARG A 1 91  ? 230.964 296.275 253.469 1.00 41.95  ? 348 ARG C CG  1 
ATOM   737  C CD  . ARG A 1 91  ? 232.158 297.193 253.374 1.00 43.42  ? 348 ARG C CD  1 
ATOM   738  N NE  . ARG A 1 91  ? 233.331 296.476 252.896 1.00 45.49  ? 348 ARG C NE  1 
ATOM   739  C CZ  . ARG A 1 91  ? 234.304 296.034 253.678 1.00 48.33  ? 348 ARG C CZ  1 
ATOM   740  N NH1 . ARG A 1 91  ? 234.275 296.219 254.987 1.00 54.14  ? 348 ARG C NH1 1 
ATOM   741  N NH2 . ARG A 1 91  ? 235.333 295.392 253.134 1.00 54.28  ? 348 ARG C NH2 1 
ATOM   742  N N   . PHE A 1 92  ? 228.362 294.391 254.176 1.00 56.47  ? 349 PHE C N   1 
ATOM   743  C CA  . PHE A 1 92  ? 227.290 294.726 255.096 1.00 58.24  ? 349 PHE C CA  1 
ATOM   744  C C   . PHE A 1 92  ? 227.452 296.157 255.599 1.00 72.22  ? 349 PHE C C   1 
ATOM   745  O O   . PHE A 1 92  ? 228.555 296.708 255.646 1.00 73.57  ? 349 PHE C O   1 
ATOM   746  C CB  . PHE A 1 92  ? 227.277 293.759 256.279 1.00 48.91  ? 349 PHE C CB  1 
ATOM   747  C CG  . PHE A 1 92  ? 226.773 292.387 255.939 1.00 55.17  ? 349 PHE C CG  1 
ATOM   748  C CD1 . PHE A 1 92  ? 225.417 292.118 255.918 1.00 60.40  ? 349 PHE C CD1 1 
ATOM   749  C CD2 . PHE A 1 92  ? 227.656 291.364 255.648 1.00 58.51  ? 349 PHE C CD2 1 
ATOM   750  C CE1 . PHE A 1 92  ? 224.952 290.854 255.609 1.00 62.25  ? 349 PHE C CE1 1 
ATOM   751  C CE2 . PHE A 1 92  ? 227.199 290.100 255.340 1.00 58.67  ? 349 PHE C CE2 1 
ATOM   752  C CZ  . PHE A 1 92  ? 225.846 289.844 255.320 1.00 58.23  ? 349 PHE C CZ  1 
ATOM   753  N N   . ASN A 1 93  ? 226.329 296.763 255.983 1.00 75.26  ? 350 ASN C N   1 
ATOM   754  C CA  . ASN A 1 93  ? 226.338 298.107 256.546 1.00 62.39  ? 350 ASN C CA  1 
ATOM   755  C C   . ASN A 1 93  ? 225.682 298.214 257.912 1.00 67.11  ? 350 ASN C C   1 
ATOM   756  O O   . ASN A 1 93  ? 226.068 299.099 258.685 1.00 71.93  ? 350 ASN C O   1 
ATOM   757  C CB  . ASN A 1 93  ? 225.651 299.096 255.594 1.00 57.09  ? 350 ASN C CB  1 
ATOM   758  C CG  . ASN A 1 93  ? 224.218 298.716 255.297 1.00 67.72  ? 350 ASN C CG  1 
ATOM   759  O OD1 . ASN A 1 93  ? 223.770 297.622 255.640 1.00 67.88  ? 350 ASN C OD1 1 
ATOM   760  N ND2 . ASN A 1 93  ? 223.486 299.620 254.657 1.00 69.63  ? 350 ASN C ND2 1 
ATOM   761  N N   . TRP A 1 94  ? 224.714 297.359 258.242 1.00 58.17  ? 351 TRP C N   1 
ATOM   762  C CA  . TRP A 1 94  ? 224.067 297.381 259.548 1.00 56.46  ? 351 TRP C CA  1 
ATOM   763  C C   . TRP A 1 94  ? 224.386 296.126 260.350 1.00 56.78  ? 351 TRP C C   1 
ATOM   764  O O   . TRP A 1 94  ? 224.914 296.221 261.461 1.00 60.04  ? 351 TRP C O   1 
ATOM   765  C CB  . TRP A 1 94  ? 222.548 297.545 259.374 1.00 53.99  ? 351 TRP C CB  1 
ATOM   766  C CG  . TRP A 1 94  ? 221.773 297.829 260.639 1.00 57.82  ? 351 TRP C CG  1 
ATOM   767  C CD1 . TRP A 1 94  ? 222.056 297.390 261.902 1.00 57.90  ? 351 TRP C CD1 1 
ATOM   768  C CD2 . TRP A 1 94  ? 220.575 298.610 260.751 1.00 67.11  ? 351 TRP C CD2 1 
ATOM   769  N NE1 . TRP A 1 94  ? 221.116 297.851 262.788 1.00 62.15  ? 351 TRP C NE1 1 
ATOM   770  C CE2 . TRP A 1 94  ? 220.195 298.603 262.107 1.00 71.47  ? 351 TRP C CE2 1 
ATOM   771  C CE3 . TRP A 1 94  ? 219.788 299.316 259.835 1.00 64.69  ? 351 TRP C CE3 1 
ATOM   772  C CZ2 . TRP A 1 94  ? 219.063 299.276 262.570 1.00 63.89  ? 351 TRP C CZ2 1 
ATOM   773  C CZ3 . TRP A 1 94  ? 218.664 299.984 260.298 1.00 58.49  ? 351 TRP C CZ3 1 
ATOM   774  C CH2 . TRP A 1 94  ? 218.313 299.957 261.652 1.00 54.17  ? 351 TRP C CH2 1 
ATOM   775  N N   . HIS A 1 95  ? 224.089 294.948 259.811 1.00 55.18  ? 352 HIS C N   1 
ATOM   776  C CA  . HIS A 1 95  ? 224.352 293.716 260.537 1.00 52.18  ? 352 HIS C CA  1 
ATOM   777  C C   . HIS A 1 95  ? 225.852 293.477 260.651 1.00 51.02  ? 352 HIS C C   1 
ATOM   778  O O   . HIS A 1 95  ? 226.628 293.790 259.745 1.00 57.17  ? 352 HIS C O   1 
ATOM   779  C CB  . HIS A 1 95  ? 223.674 292.531 259.852 1.00 55.72  ? 352 HIS C CB  1 
ATOM   780  C CG  . HIS A 1 95  ? 222.314 292.220 260.391 1.00 59.25  ? 352 HIS C CG  1 
ATOM   781  N ND1 . HIS A 1 95  ? 222.059 292.093 261.739 1.00 55.79  ? 352 HIS C ND1 1 
ATOM   782  C CD2 . HIS A 1 95  ? 221.132 292.007 259.764 1.00 55.58  ? 352 HIS C CD2 1 
ATOM   783  C CE1 . HIS A 1 95  ? 220.779 291.821 261.919 1.00 53.81  ? 352 HIS C CE1 1 
ATOM   784  N NE2 . HIS A 1 95  ? 220.195 291.763 260.737 1.00 55.28  ? 352 HIS C NE2 1 
ATOM   785  N N   . TYR A 1 96  ? 226.256 292.920 261.786 1.00 45.83  ? 353 TYR C N   1 
ATOM   786  C CA  . TYR A 1 96  ? 227.669 292.759 262.119 1.00 44.68  ? 353 TYR C CA  1 
ATOM   787  C C   . TYR A 1 96  ? 228.197 291.400 261.667 1.00 53.12  ? 353 TYR C C   1 
ATOM   788  O O   . TYR A 1 96  ? 228.844 290.690 262.432 1.00 56.06  ? 353 TYR C O   1 
ATOM   789  C CB  . TYR A 1 96  ? 227.854 292.933 263.623 1.00 45.15  ? 353 TYR C CB  1 
ATOM   790  C CG  . TYR A 1 96  ? 227.570 294.321 264.164 1.00 53.29  ? 353 TYR C CG  1 
ATOM   791  C CD1 . TYR A 1 96  ? 226.317 294.907 264.029 1.00 64.98  ? 353 TYR C CD1 1 
ATOM   792  C CD2 . TYR A 1 96  ? 228.542 295.026 264.848 1.00 49.00  ? 353 TYR C CD2 1 
ATOM   793  C CE1 . TYR A 1 96  ? 226.058 296.169 264.534 1.00 58.55  ? 353 TYR C CE1 1 
ATOM   794  C CE2 . TYR A 1 96  ? 228.294 296.285 265.358 1.00 45.98  ? 353 TYR C CE2 1 
ATOM   795  C CZ  . TYR A 1 96  ? 227.052 296.851 265.199 1.00 46.83  ? 353 TYR C CZ  1 
ATOM   796  O OH  . TYR A 1 96  ? 226.801 298.102 265.706 1.00 39.28  ? 353 TYR C OH  1 
ATOM   797  N N   . CYS A 1 97  ? 227.953 291.031 260.413 1.00 63.98  ? 354 CYS C N   1 
ATOM   798  C CA  . CYS A 1 97  ? 228.201 289.671 259.951 1.00 61.81  ? 354 CYS C CA  1 
ATOM   799  C C   . CYS A 1 97  ? 229.289 289.623 258.890 1.00 55.11  ? 354 CYS C C   1 
ATOM   800  O O   . CYS A 1 97  ? 229.439 290.548 258.087 1.00 61.55  ? 354 CYS C O   1 
ATOM   801  C CB  . CYS A 1 97  ? 226.924 289.036 259.400 1.00 59.78  ? 354 CYS C CB  1 
ATOM   802  S SG  . CYS A 1 97  ? 225.408 289.596 260.188 1.00 75.92  ? 354 CYS C SG  1 
ATOM   803  N N   . VAL A 1 98  ? 230.044 288.529 258.898 1.00 44.06  ? 355 VAL C N   1 
ATOM   804  C CA  . VAL A 1 98  ? 231.106 288.275 257.937 1.00 38.39  ? 355 VAL C CA  1 
ATOM   805  C C   . VAL A 1 98  ? 230.950 286.847 257.430 1.00 45.80  ? 355 VAL C C   1 
ATOM   806  O O   . VAL A 1 98  ? 230.516 285.957 258.172 1.00 61.17  ? 355 VAL C O   1 
ATOM   807  C CB  . VAL A 1 98  ? 232.502 288.508 258.560 1.00 44.56  ? 355 VAL C CB  1 
ATOM   808  C CG1 . VAL A 1 98  ? 232.762 287.529 259.692 1.00 56.88  ? 355 VAL C CG1 1 
ATOM   809  C CG2 . VAL A 1 98  ? 233.592 288.421 257.504 1.00 45.26  ? 355 VAL C CG2 1 
ATOM   810  N N   . LEU A 1 99  ? 231.277 286.636 256.159 1.00 45.77  ? 356 LEU C N   1 
ATOM   811  C CA  . LEU A 1 99  ? 231.095 285.355 255.493 1.00 51.44  ? 356 LEU C CA  1 
ATOM   812  C C   . LEU A 1 99  ? 232.436 284.806 255.019 1.00 55.17  ? 356 LEU C C   1 
ATOM   813  O O   . LEU A 1 99  ? 233.504 285.345 255.320 1.00 57.82  ? 356 LEU C O   1 
ATOM   814  C CB  . LEU A 1 99  ? 230.122 285.492 254.320 1.00 50.53  ? 356 LEU C CB  1 
ATOM   815  C CG  . LEU A 1 99  ? 228.966 286.478 254.479 1.00 54.57  ? 356 LEU C CG  1 
ATOM   816  C CD1 . LEU A 1 99  ? 228.276 286.702 253.148 1.00 52.04  ? 356 LEU C CD1 1 
ATOM   817  C CD2 . LEU A 1 99  ? 227.980 285.980 255.517 1.00 56.81  ? 356 LEU C CD2 1 
ATOM   818  N N   . GLY A 1 100 ? 232.366 283.708 254.270 1.00 52.78  ? 357 GLY C N   1 
ATOM   819  C CA  . GLY A 1 100 ? 233.539 283.111 253.666 1.00 46.66  ? 357 GLY C CA  1 
ATOM   820  C C   . GLY A 1 100 ? 233.589 283.342 252.171 1.00 48.28  ? 357 GLY C C   1 
ATOM   821  O O   . GLY A 1 100 ? 232.568 283.660 251.555 1.00 50.48  ? 357 GLY C O   1 
ATOM   822  N N   . CYS A 1 101 ? 234.770 283.188 251.572 1.00 68.91  ? 358 CYS C N   1 
ATOM   823  C CA  . CYS A 1 101 ? 234.924 283.463 250.148 1.00 77.42  ? 358 CYS C CA  1 
ATOM   824  C C   . CYS A 1 101 ? 234.299 282.389 249.267 1.00 81.14  ? 358 CYS C C   1 
ATOM   825  O O   . CYS A 1 101 ? 234.117 282.622 248.067 1.00 80.44  ? 358 CYS C O   1 
ATOM   826  C CB  . CYS A 1 101 ? 236.405 283.610 249.796 1.00 77.72  ? 358 CYS C CB  1 
ATOM   827  S SG  . CYS A 1 101 ? 237.074 285.274 250.011 1.00 95.70  ? 358 CYS C SG  1 
ATOM   828  N N   . GLU A 1 102 ? 233.968 281.228 249.823 1.00 73.17  ? 359 GLU C N   1 
ATOM   829  C CA  . GLU A 1 102 ? 233.504 280.088 249.047 1.00 60.82  ? 359 GLU C CA  1 
ATOM   830  C C   . GLU A 1 102 ? 232.120 279.658 249.508 1.00 58.59  ? 359 GLU C C   1 
ATOM   831  O O   . GLU A 1 102 ? 231.847 279.598 250.711 1.00 60.45  ? 359 GLU C O   1 
ATOM   832  C CB  . GLU A 1 102 ? 234.477 278.914 249.170 1.00 59.41  ? 359 GLU C CB  1 
ATOM   833  C CG  . GLU A 1 102 ? 235.909 279.248 248.787 1.00 66.42  ? 359 GLU C CG  1 
ATOM   834  C CD  . GLU A 1 102 ? 236.683 279.897 249.918 1.00 73.14  ? 359 GLU C CD  1 
ATOM   835  O OE1 . GLU A 1 102 ? 236.153 279.952 251.047 1.00 76.10  ? 359 GLU C OE1 1 
ATOM   836  O OE2 . GLU A 1 102 ? 237.820 280.354 249.677 1.00 73.97  ? 359 GLU C OE2 1 
ATOM   837  N N   . SER A 1 103 ? 231.253 279.354 248.548 1.00 55.06  ? 360 SER C N   1 
ATOM   838  C CA  . SER A 1 103 ? 229.911 278.863 248.823 1.00 60.54  ? 360 SER C CA  1 
ATOM   839  C C   . SER A 1 103 ? 229.814 277.394 248.435 1.00 68.47  ? 360 SER C C   1 
ATOM   840  O O   . SER A 1 103 ? 230.331 276.981 247.392 1.00 72.82  ? 360 SER C O   1 
ATOM   841  C CB  . SER A 1 103 ? 228.856 279.671 248.066 1.00 50.92  ? 360 SER C CB  1 
ATOM   842  O OG  . SER A 1 103 ? 228.722 279.209 246.735 1.00 53.60  ? 360 SER C OG  1 
ATOM   843  N N   . PHE A 1 104 ? 229.148 276.610 249.279 1.00 70.91  ? 361 PHE C N   1 
ATOM   844  C CA  . PHE A 1 104 ? 229.006 275.171 249.066 1.00 65.81  ? 361 PHE C CA  1 
ATOM   845  C C   . PHE A 1 104 ? 227.715 274.930 248.297 1.00 66.62  ? 361 PHE C C   1 
ATOM   846  O O   . PHE A 1 104 ? 226.619 274.938 248.857 1.00 70.06  ? 361 PHE C O   1 
ATOM   847  C CB  . PHE A 1 104 ? 229.021 274.434 250.396 1.00 61.10  ? 361 PHE C CB  1 
ATOM   848  C CG  . PHE A 1 104 ? 230.135 274.857 251.303 1.00 55.05  ? 361 PHE C CG  1 
ATOM   849  C CD1 . PHE A 1 104 ? 231.454 274.711 250.913 1.00 56.41  ? 361 PHE C CD1 1 
ATOM   850  C CD2 . PHE A 1 104 ? 229.865 275.410 252.539 1.00 60.82  ? 361 PHE C CD2 1 
ATOM   851  C CE1 . PHE A 1 104 ? 232.482 275.100 251.742 1.00 62.91  ? 361 PHE C CE1 1 
ATOM   852  C CE2 . PHE A 1 104 ? 230.890 275.803 253.372 1.00 69.10  ? 361 PHE C CE2 1 
ATOM   853  C CZ  . PHE A 1 104 ? 232.200 275.648 252.973 1.00 68.52  ? 361 PHE C CZ  1 
ATOM   854  N N   . ILE A 1 105 ? 227.851 274.711 246.987 1.00 56.63  ? 362 ILE C N   1 
ATOM   855  C CA  . ILE A 1 105 ? 226.681 274.549 246.136 1.00 59.17  ? 362 ILE C CA  1 
ATOM   856  C C   . ILE A 1 105 ? 225.917 273.272 246.457 1.00 60.31  ? 362 ILE C C   1 
ATOM   857  O O   . ILE A 1 105 ? 224.684 273.265 246.386 1.00 54.53  ? 362 ILE C O   1 
ATOM   858  C CB  . ILE A 1 105 ? 227.093 274.597 244.651 1.00 64.63  ? 362 ILE C CB  1 
ATOM   859  C CG1 . ILE A 1 105 ? 225.861 274.561 243.740 1.00 66.87  ? 362 ILE C CG1 1 
ATOM   860  C CG2 . ILE A 1 105 ? 228.070 273.478 244.315 1.00 64.04  ? 362 ILE C CG2 1 
ATOM   861  C CD1 . ILE A 1 105 ? 224.754 275.512 244.152 1.00 64.48  ? 362 ILE C CD1 1 
ATOM   862  N N   . SER A 1 106 ? 226.605 272.193 246.819 1.00 81.38  ? 363 SER C N   1 
ATOM   863  C CA  . SER A 1 106 ? 225.943 270.924 247.099 1.00 82.70  ? 363 SER C CA  1 
ATOM   864  C C   . SER A 1 106 ? 226.879 270.055 247.928 1.00 74.23  ? 363 SER C C   1 
ATOM   865  O O   . SER A 1 106 ? 228.040 270.402 248.163 1.00 71.00  ? 363 SER C O   1 
ATOM   866  C CB  . SER A 1 106 ? 225.535 270.205 245.810 1.00 78.96  ? 363 SER C CB  1 
ATOM   867  O OG  . SER A 1 106 ? 224.436 270.850 245.190 1.00 79.92  ? 363 SER C OG  1 
ATOM   868  N N   . GLY A 1 107 ? 226.353 268.921 248.370 1.00 69.24  ? 364 GLY C N   1 
ATOM   869  C CA  . GLY A 1 107 ? 227.133 267.938 249.089 1.00 74.68  ? 364 GLY C CA  1 
ATOM   870  C C   . GLY A 1 107 ? 226.999 268.055 250.593 1.00 73.88  ? 364 GLY C C   1 
ATOM   871  O O   . GLY A 1 107 ? 226.081 268.680 251.130 1.00 71.14  ? 364 GLY C O   1 
ATOM   872  N N   . ARG A 1 108 ? 227.949 267.426 251.283 1.00 65.55  ? 365 ARG C N   1 
ATOM   873  C CA  . ARG A 1 108 ? 228.008 267.436 252.739 1.00 59.56  ? 365 ARG C CA  1 
ATOM   874  C C   . ARG A 1 108 ? 229.371 267.957 253.166 1.00 60.26  ? 365 ARG C C   1 
ATOM   875  O O   . ARG A 1 108 ? 230.401 267.410 252.761 1.00 57.25  ? 365 ARG C O   1 
ATOM   876  C CB  . ARG A 1 108 ? 227.757 266.039 253.308 1.00 60.44  ? 365 ARG C CB  1 
ATOM   877  C CG  . ARG A 1 108 ? 226.353 265.522 253.055 1.00 64.22  ? 365 ARG C CG  1 
ATOM   878  C CD  . ARG A 1 108 ? 226.112 264.193 253.751 1.00 63.90  ? 365 ARG C CD  1 
ATOM   879  N NE  . ARG A 1 108 ? 225.064 263.424 253.094 1.00 65.52  ? 365 ARG C NE  1 
ATOM   880  C CZ  . ARG A 1 108 ? 225.263 262.628 252.053 1.00 62.69  ? 365 ARG C CZ  1 
ATOM   881  N NH1 . ARG A 1 108 ? 226.468 262.456 251.536 1.00 61.44  ? 365 ARG C NH1 1 
ATOM   882  N NH2 . ARG A 1 108 ? 224.227 261.991 251.515 1.00 60.52  ? 365 ARG C NH2 1 
ATOM   883  N N   . HIS A 1 109 ? 229.373 269.011 253.979 1.00 60.48  ? 366 HIS C N   1 
ATOM   884  C CA  . HIS A 1 109 ? 230.604 269.645 254.430 1.00 56.44  ? 366 HIS C CA  1 
ATOM   885  C C   . HIS A 1 109 ? 230.472 270.008 255.903 1.00 61.07  ? 366 HIS C C   1 
ATOM   886  O O   . HIS A 1 109 ? 229.382 269.960 256.477 1.00 63.34  ? 366 HIS C O   1 
ATOM   887  C CB  . HIS A 1 109 ? 230.938 270.891 253.598 1.00 52.81  ? 366 HIS C CB  1 
ATOM   888  C CG  . HIS A 1 109 ? 230.613 270.753 252.142 1.00 62.66  ? 366 HIS C CG  1 
ATOM   889  N ND1 . HIS A 1 109 ? 231.574 270.516 251.183 1.00 66.34  ? 366 HIS C ND1 1 
ATOM   890  C CD2 . HIS A 1 109 ? 229.434 270.826 251.480 1.00 65.78  ? 366 HIS C CD2 1 
ATOM   891  C CE1 . HIS A 1 109 ? 231.001 270.445 249.995 1.00 61.62  ? 366 HIS C CE1 1 
ATOM   892  N NE2 . HIS A 1 109 ? 229.703 270.629 250.147 1.00 59.59  ? 366 HIS C NE2 1 
ATOM   893  N N   . TYR A 1 110 ? 231.599 270.353 256.525 1.00 51.09  ? 367 TYR C N   1 
ATOM   894  C CA  . TYR A 1 110 ? 231.578 270.721 257.933 1.00 47.66  ? 367 TYR C CA  1 
ATOM   895  C C   . TYR A 1 110 ? 232.749 271.638 258.242 1.00 50.40  ? 367 TYR C C   1 
ATOM   896  O O   . TYR A 1 110 ? 233.768 271.633 257.548 1.00 62.74  ? 367 TYR C O   1 
ATOM   897  C CB  . TYR A 1 110 ? 231.628 269.489 258.843 1.00 49.97  ? 367 TYR C CB  1 
ATOM   898  C CG  . TYR A 1 110 ? 232.998 269.154 259.394 1.00 53.87  ? 367 TYR C CG  1 
ATOM   899  C CD1 . TYR A 1 110 ? 233.910 268.420 258.654 1.00 57.59  ? 367 TYR C CD1 1 
ATOM   900  C CD2 . TYR A 1 110 ? 233.366 269.552 260.672 1.00 57.01  ? 367 TYR C CD2 1 
ATOM   901  C CE1 . TYR A 1 110 ? 235.156 268.110 259.164 1.00 51.44  ? 367 TYR C CE1 1 
ATOM   902  C CE2 . TYR A 1 110 ? 234.609 269.246 261.186 1.00 56.92  ? 367 TYR C CE2 1 
ATOM   903  C CZ  . TYR A 1 110 ? 235.499 268.524 260.427 1.00 53.15  ? 367 TYR C CZ  1 
ATOM   904  O OH  . TYR A 1 110 ? 236.738 268.214 260.931 1.00 59.29  ? 367 TYR C OH  1 
ATOM   905  N N   . TRP A 1 111 ? 232.594 272.424 259.305 1.00 40.16  ? 368 TRP C N   1 
ATOM   906  C CA  . TRP A 1 111 ? 233.681 273.283 259.757 1.00 42.65  ? 368 TRP C CA  1 
ATOM   907  C C   . TRP A 1 111 ? 233.585 273.509 261.258 1.00 44.53  ? 368 TRP C C   1 
ATOM   908  O O   . TRP A 1 111 ? 232.488 273.569 261.819 1.00 44.65  ? 368 TRP C O   1 
ATOM   909  C CB  . TRP A 1 111 ? 233.691 274.627 259.016 1.00 47.03  ? 368 TRP C CB  1 
ATOM   910  C CG  . TRP A 1 111 ? 232.399 275.379 259.053 1.00 47.43  ? 368 TRP C CG  1 
ATOM   911  C CD1 . TRP A 1 111 ? 232.046 276.358 259.933 1.00 54.23  ? 368 TRP C CD1 1 
ATOM   912  C CD2 . TRP A 1 111 ? 231.296 275.232 258.153 1.00 48.06  ? 368 TRP C CD2 1 
ATOM   913  N NE1 . TRP A 1 111 ? 230.787 276.821 259.646 1.00 54.07  ? 368 TRP C NE1 1 
ATOM   914  C CE2 . TRP A 1 111 ? 230.305 276.145 258.556 1.00 50.94  ? 368 TRP C CE2 1 
ATOM   915  C CE3 . TRP A 1 111 ? 231.048 274.413 257.050 1.00 52.15  ? 368 TRP C CE3 1 
ATOM   916  C CZ2 . TRP A 1 111 ? 229.086 276.261 257.896 1.00 48.50  ? 368 TRP C CZ2 1 
ATOM   917  C CZ3 . TRP A 1 111 ? 229.837 274.530 256.396 1.00 51.00  ? 368 TRP C CZ3 1 
ATOM   918  C CH2 . TRP A 1 111 ? 228.872 275.446 256.820 1.00 46.87  ? 368 TRP C CH2 1 
ATOM   919  N N   . GLU A 1 112 ? 234.744 273.646 261.898 1.00 57.28  ? 369 GLU C N   1 
ATOM   920  C CA  . GLU A 1 112 ? 234.835 273.818 263.342 1.00 60.52  ? 369 GLU C CA  1 
ATOM   921  C C   . GLU A 1 112 ? 235.156 275.268 263.669 1.00 62.20  ? 369 GLU C C   1 
ATOM   922  O O   . GLU A 1 112 ? 236.100 275.842 263.115 1.00 69.05  ? 369 GLU C O   1 
ATOM   923  C CB  . GLU A 1 112 ? 235.904 272.902 263.938 1.00 60.13  ? 369 GLU C CB  1 
ATOM   924  C CG  . GLU A 1 112 ? 235.539 271.431 263.939 1.00 66.10  ? 369 GLU C CG  1 
ATOM   925  C CD  . GLU A 1 112 ? 236.759 270.533 263.949 1.00 70.51  ? 369 GLU C CD  1 
ATOM   926  O OE1 . GLU A 1 112 ? 237.889 271.064 263.939 1.00 69.70  ? 369 GLU C OE1 1 
ATOM   927  O OE2 . GLU A 1 112 ? 236.589 269.296 263.966 1.00 74.54  ? 369 GLU C OE2 1 
ATOM   928  N N   . VAL A 1 113 ? 234.369 275.856 264.565 1.00 54.75  ? 370 VAL C N   1 
ATOM   929  C CA  . VAL A 1 113 ? 234.558 277.226 265.017 1.00 53.36  ? 370 VAL C CA  1 
ATOM   930  C C   . VAL A 1 113 ? 234.653 277.194 266.532 1.00 52.86  ? 370 VAL C C   1 
ATOM   931  O O   . VAL A 1 113 ? 233.740 276.700 267.203 1.00 62.72  ? 370 VAL C O   1 
ATOM   932  C CB  . VAL A 1 113 ? 233.408 278.139 264.565 1.00 56.90  ? 370 VAL C CB  1 
ATOM   933  C CG1 . VAL A 1 113 ? 233.658 279.568 265.018 1.00 63.37  ? 370 VAL C CG1 1 
ATOM   934  C CG2 . VAL A 1 113 ? 233.229 278.069 263.059 1.00 59.48  ? 370 VAL C CG2 1 
ATOM   935  N N   . GLU A 1 114 ? 235.742 277.719 267.074 1.00 53.29  ? 371 GLU C N   1 
ATOM   936  C CA  . GLU A 1 114 ? 235.888 277.779 268.519 1.00 59.59  ? 371 GLU C CA  1 
ATOM   937  C C   . GLU A 1 114 ? 235.423 279.142 269.014 1.00 61.97  ? 371 GLU C C   1 
ATOM   938  O O   . GLU A 1 114 ? 235.890 280.181 268.537 1.00 71.60  ? 371 GLU C O   1 
ATOM   939  C CB  . GLU A 1 114 ? 237.331 277.490 268.946 1.00 66.44  ? 371 GLU C CB  1 
ATOM   940  C CG  . GLU A 1 114 ? 238.372 278.494 268.495 1.00 69.45  ? 371 GLU C CG  1 
ATOM   941  C CD  . GLU A 1 114 ? 238.688 279.517 269.569 1.00 72.87  ? 371 GLU C CD  1 
ATOM   942  O OE1 . GLU A 1 114 ? 238.456 279.220 270.760 1.00 76.21  ? 371 GLU C OE1 1 
ATOM   943  O OE2 . GLU A 1 114 ? 239.164 280.619 269.226 1.00 66.98  ? 371 GLU C OE2 1 
ATOM   944  N N   . VAL A 1 115 ? 234.467 279.134 269.939 1.00 52.07  ? 372 VAL C N   1 
ATOM   945  C CA  . VAL A 1 115 ? 233.984 280.374 270.530 1.00 60.15  ? 372 VAL C CA  1 
ATOM   946  C C   . VAL A 1 115 ? 234.717 280.719 271.821 1.00 61.60  ? 372 VAL C C   1 
ATOM   947  O O   . VAL A 1 115 ? 234.716 281.893 272.222 1.00 63.04  ? 372 VAL C O   1 
ATOM   948  C CB  . VAL A 1 115 ? 232.463 280.318 270.781 1.00 59.49  ? 372 VAL C CB  1 
ATOM   949  C CG1 . VAL A 1 115 ? 231.732 279.917 269.512 1.00 59.62  ? 372 VAL C CG1 1 
ATOM   950  C CG2 . VAL A 1 115 ? 232.142 279.360 271.913 1.00 59.04  ? 372 VAL C CG2 1 
ATOM   951  N N   . GLY A 1 116 ? 235.347 279.746 272.473 1.00 72.30  ? 373 GLY C N   1 
ATOM   952  C CA  . GLY A 1 116 ? 236.041 280.018 273.711 1.00 74.52  ? 373 GLY C CA  1 
ATOM   953  C C   . GLY A 1 116 ? 235.080 280.472 274.799 1.00 73.53  ? 373 GLY C C   1 
ATOM   954  O O   . GLY A 1 116 ? 233.888 280.153 274.803 1.00 70.85  ? 373 GLY C O   1 
ATOM   955  N N   . ASP A 1 117 ? 235.625 281.241 275.734 1.00 76.48  ? 374 ASP C N   1 
ATOM   956  C CA  . ASP A 1 117 ? 234.826 281.829 276.807 1.00 75.64  ? 374 ASP C CA  1 
ATOM   957  C C   . ASP A 1 117 ? 234.201 283.173 276.424 1.00 77.32  ? 374 ASP C C   1 
ATOM   958  O O   . ASP A 1 117 ? 234.092 284.109 277.215 1.00 83.24  ? 374 ASP C O   1 
ATOM   959  C CB  . ASP A 1 117 ? 235.679 281.877 278.082 1.00 78.26  ? 374 ASP C CB  1 
ATOM   960  C CG  . ASP A 1 117 ? 236.518 283.161 278.257 1.00 83.52  ? 374 ASP C CG  1 
ATOM   961  O OD1 . ASP A 1 117 ? 236.574 284.055 277.386 1.00 83.97  ? 374 ASP C OD1 1 
ATOM   962  O OD2 . ASP A 1 117 ? 237.150 283.271 279.328 1.00 84.00  ? 374 ASP C OD2 1 
ATOM   963  N N   . ARG A 1 118 ? 233.638 283.212 275.221 1.00 57.36  ? 375 ARG C N   1 
ATOM   964  C CA  . ARG A 1 118 ? 232.976 284.415 274.748 1.00 55.39  ? 375 ARG C CA  1 
ATOM   965  C C   . ARG A 1 118 ? 231.621 284.576 275.426 1.00 57.52  ? 375 ARG C C   1 
ATOM   966  O O   . ARG A 1 118 ? 231.098 283.655 276.058 1.00 59.24  ? 375 ARG C O   1 
ATOM   967  C CB  . ARG A 1 118 ? 232.801 284.379 273.230 1.00 59.17  ? 375 ARG C CB  1 
ATOM   968  C CG  . ARG A 1 118 ? 233.936 285.030 272.462 1.00 57.89  ? 375 ARG C CG  1 
ATOM   969  C CD  . ARG A 1 118 ? 233.560 285.258 271.009 1.00 56.84  ? 375 ARG C CD  1 
ATOM   970  N NE  . ARG A 1 118 ? 232.516 286.265 270.873 1.00 55.43  ? 375 ARG C NE  1 
ATOM   971  C CZ  . ARG A 1 118 ? 232.743 287.566 270.770 1.00 50.37  ? 375 ARG C CZ  1 
ATOM   972  N NH1 . ARG A 1 118 ? 233.972 288.055 270.771 1.00 48.96  ? 375 ARG C NH1 1 
ATOM   973  N NH2 . ARG A 1 118 ? 231.711 288.398 270.664 1.00 51.48  ? 375 ARG C NH2 1 
ATOM   974  N N   . LYS A 1 119 ? 231.055 285.772 275.291 1.00 61.66  ? 376 LYS C N   1 
ATOM   975  C CA  . LYS A 1 119 ? 229.772 286.088 275.896 1.00 65.53  ? 376 LYS C CA  1 
ATOM   976  C C   . LYS A 1 119 ? 228.720 286.512 274.883 1.00 64.05  ? 376 LYS C C   1 
ATOM   977  O O   . LYS A 1 119 ? 227.578 286.776 275.277 1.00 67.19  ? 376 LYS C O   1 
ATOM   978  C CB  . LYS A 1 119 ? 229.942 287.188 276.952 1.00 67.12  ? 376 LYS C CB  1 
ATOM   979  C CG  . LYS A 1 119 ? 231.236 287.087 277.744 1.00 66.51  ? 376 LYS C CG  1 
ATOM   980  C CD  . LYS A 1 119 ? 231.118 286.074 278.866 1.00 62.40  ? 376 LYS C CD  1 
ATOM   981  C CE  . LYS A 1 119 ? 231.656 286.633 280.167 1.00 61.97  ? 376 LYS C CE  1 
ATOM   982  N NZ  . LYS A 1 119 ? 231.233 285.817 281.334 1.00 64.54  ? 376 LYS C NZ  1 
ATOM   983  N N   . GLU A 1 120 ? 229.065 286.592 273.601 1.00 59.17  ? 377 GLU C N   1 
ATOM   984  C CA  . GLU A 1 120 ? 228.096 286.957 272.571 1.00 58.53  ? 377 GLU C CA  1 
ATOM   985  C C   . GLU A 1 120 ? 228.648 286.538 271.220 1.00 58.58  ? 377 GLU C C   1 
ATOM   986  O O   . GLU A 1 120 ? 229.676 287.066 270.784 1.00 61.21  ? 377 GLU C O   1 
ATOM   987  C CB  . GLU A 1 120 ? 227.812 288.456 272.593 1.00 58.94  ? 377 GLU C CB  1 
ATOM   988  C CG  . GLU A 1 120 ? 226.339 288.811 272.511 1.00 66.20  ? 377 GLU C CG  1 
ATOM   989  C CD  . GLU A 1 120 ? 225.725 288.463 271.170 1.00 69.25  ? 377 GLU C CD  1 
ATOM   990  O OE1 . GLU A 1 120 ? 226.465 288.421 270.165 1.00 70.32  ? 377 GLU C OE1 1 
ATOM   991  O OE2 . GLU A 1 120 ? 224.498 288.236 271.120 1.00 70.67  ? 377 GLU C OE2 1 
ATOM   992  N N   . TRP A 1 121 ? 227.975 285.600 270.560 1.00 49.82  ? 378 TRP C N   1 
ATOM   993  C CA  . TRP A 1 121 ? 228.355 285.205 269.212 1.00 48.27  ? 378 TRP C CA  1 
ATOM   994  C C   . TRP A 1 121 ? 227.147 284.596 268.519 1.00 51.45  ? 378 TRP C C   1 
ATOM   995  O O   . TRP A 1 121 ? 226.184 284.173 269.164 1.00 62.31  ? 378 TRP C O   1 
ATOM   996  C CB  . TRP A 1 121 ? 229.532 284.221 269.214 1.00 53.33  ? 378 TRP C CB  1 
ATOM   997  C CG  . TRP A 1 121 ? 229.372 283.043 270.131 1.00 57.61  ? 378 TRP C CG  1 
ATOM   998  C CD1 . TRP A 1 121 ? 229.926 282.890 271.367 1.00 58.64  ? 378 TRP C CD1 1 
ATOM   999  C CD2 . TRP A 1 121 ? 228.629 281.843 269.874 1.00 55.51  ? 378 TRP C CD2 1 
ATOM   1000 N NE1 . TRP A 1 121 ? 229.567 281.676 271.901 1.00 59.77  ? 378 TRP C NE1 1 
ATOM   1001 C CE2 . TRP A 1 121 ? 228.771 281.015 271.003 1.00 55.40  ? 378 TRP C CE2 1 
ATOM   1002 C CE3 . TRP A 1 121 ? 227.855 281.392 268.802 1.00 51.62  ? 378 TRP C CE3 1 
ATOM   1003 C CZ2 . TRP A 1 121 ? 228.169 279.765 271.091 1.00 52.46  ? 378 TRP C CZ2 1 
ATOM   1004 C CZ3 . TRP A 1 121 ? 227.257 280.151 268.893 1.00 45.58  ? 378 TRP C CZ3 1 
ATOM   1005 C CH2 . TRP A 1 121 ? 227.417 279.352 270.027 1.00 49.67  ? 378 TRP C CH2 1 
ATOM   1006 N N   . HIS A 1 122 ? 227.210 284.567 267.189 1.00 41.55  ? 379 HIS C N   1 
ATOM   1007 C CA  . HIS A 1 122 ? 226.173 283.926 266.388 1.00 42.00  ? 379 HIS C CA  1 
ATOM   1008 C C   . HIS A 1 122 ? 226.818 283.384 265.125 1.00 44.00  ? 379 HIS C C   1 
ATOM   1009 O O   . HIS A 1 122 ? 227.241 284.164 264.269 1.00 48.26  ? 379 HIS C O   1 
ATOM   1010 C CB  . HIS A 1 122 ? 225.065 284.915 266.033 1.00 48.22  ? 379 HIS C CB  1 
ATOM   1011 C CG  . HIS A 1 122 ? 224.150 285.240 267.170 1.00 51.21  ? 379 HIS C CG  1 
ATOM   1012 N ND1 . HIS A 1 122 ? 224.487 286.132 268.165 1.00 58.22  ? 379 HIS C ND1 1 
ATOM   1013 C CD2 . HIS A 1 122 ? 222.894 284.824 267.449 1.00 45.95  ? 379 HIS C CD2 1 
ATOM   1014 C CE1 . HIS A 1 122 ? 223.487 286.230 269.022 1.00 60.53  ? 379 HIS C CE1 1 
ATOM   1015 N NE2 . HIS A 1 122 ? 222.508 285.446 268.610 1.00 58.32  ? 379 HIS C NE2 1 
ATOM   1016 N N   . ILE A 1 123 ? 226.892 282.061 264.998 1.00 43.32  ? 380 ILE C N   1 
ATOM   1017 C CA  . ILE A 1 123 ? 227.443 281.432 263.807 1.00 50.39  ? 380 ILE C CA  1 
ATOM   1018 C C   . ILE A 1 123 ? 226.366 280.557 263.179 1.00 51.99  ? 380 ILE C C   1 
ATOM   1019 O O   . ILE A 1 123 ? 225.488 280.021 263.858 1.00 46.82  ? 380 ILE C O   1 
ATOM   1020 C CB  . ILE A 1 123 ? 228.723 280.615 264.098 1.00 48.81  ? 380 ILE C CB  1 
ATOM   1021 C CG1 . ILE A 1 123 ? 228.389 279.186 264.519 1.00 52.13  ? 380 ILE C CG1 1 
ATOM   1022 C CG2 . ILE A 1 123 ? 229.557 281.290 265.169 1.00 44.83  ? 380 ILE C CG2 1 
ATOM   1023 C CD1 . ILE A 1 123 ? 229.611 278.334 264.767 1.00 38.98  ? 380 ILE C CD1 1 
ATOM   1024 N N   . GLY A 1 124 ? 226.427 280.444 261.859 1.00 46.45  ? 381 GLY C N   1 
ATOM   1025 C CA  . GLY A 1 124 ? 225.448 279.643 261.150 1.00 40.50  ? 381 GLY C CA  1 
ATOM   1026 C C   . GLY A 1 124 ? 225.714 279.658 259.656 1.00 42.63  ? 381 GLY C C   1 
ATOM   1027 O O   . GLY A 1 124 ? 226.812 279.981 259.209 1.00 44.04  ? 381 GLY C O   1 
ATOM   1028 N N   . VAL A 1 125 ? 224.672 279.315 258.906 1.00 47.94  ? 382 VAL C N   1 
ATOM   1029 C CA  . VAL A 1 125 ? 224.717 279.265 257.451 1.00 51.23  ? 382 VAL C CA  1 
ATOM   1030 C C   . VAL A 1 125 ? 223.663 280.217 256.902 1.00 50.31  ? 382 VAL C C   1 
ATOM   1031 O O   . VAL A 1 125 ? 222.493 280.154 257.297 1.00 60.44  ? 382 VAL C O   1 
ATOM   1032 C CB  . VAL A 1 125 ? 224.494 277.835 256.928 1.00 54.05  ? 382 VAL C CB  1 
ATOM   1033 C CG1 . VAL A 1 125 ? 223.991 277.863 255.506 1.00 52.35  ? 382 VAL C CG1 1 
ATOM   1034 C CG2 . VAL A 1 125 ? 225.774 277.038 257.016 1.00 55.69  ? 382 VAL C CG2 1 
ATOM   1035 N N   . CYS A 1 126 ? 224.078 281.095 255.997 1.00 46.67  ? 383 CYS C N   1 
ATOM   1036 C CA  . CYS A 1 126 ? 223.191 282.035 255.333 1.00 52.03  ? 383 CYS C CA  1 
ATOM   1037 C C   . CYS A 1 126 ? 223.126 281.713 253.846 1.00 57.16  ? 383 CYS C C   1 
ATOM   1038 O O   . CYS A 1 126 ? 223.932 280.946 253.315 1.00 62.65  ? 383 CYS C O   1 
ATOM   1039 C CB  . CYS A 1 126 ? 223.657 283.481 255.549 1.00 60.17  ? 383 CYS C CB  1 
ATOM   1040 S SG  . CYS A 1 126 ? 225.126 283.944 254.609 1.00 86.34  ? 383 CYS C SG  1 
ATOM   1041 N N   . SER A 1 127 ? 222.149 282.307 253.172 1.00 55.40  ? 384 SER C N   1 
ATOM   1042 C CA  . SER A 1 127 ? 221.980 282.111 251.739 1.00 52.17  ? 384 SER C CA  1 
ATOM   1043 C C   . SER A 1 127 ? 222.953 283.016 250.982 1.00 56.32  ? 384 SER C C   1 
ATOM   1044 O O   . SER A 1 127 ? 223.859 283.623 251.559 1.00 54.62  ? 384 SER C O   1 
ATOM   1045 C CB  . SER A 1 127 ? 220.528 282.366 251.344 1.00 49.93  ? 384 SER C CB  1 
ATOM   1046 O OG  . SER A 1 127 ? 220.323 282.144 249.962 1.00 52.24  ? 384 SER C OG  1 
ATOM   1047 N N   . LYS A 1 128 ? 222.779 283.105 249.663 1.00 57.78  ? 385 LYS C N   1 
ATOM   1048 C CA  . LYS A 1 128 ? 223.538 284.030 248.836 1.00 48.87  ? 385 LYS C CA  1 
ATOM   1049 C C   . LYS A 1 128 ? 222.730 285.247 248.408 1.00 50.63  ? 385 LYS C C   1 
ATOM   1050 O O   . LYS A 1 128 ? 223.317 286.307 248.170 1.00 54.15  ? 385 LYS C O   1 
ATOM   1051 C CB  . LYS A 1 128 ? 224.070 283.307 247.587 1.00 50.72  ? 385 LYS C CB  1 
ATOM   1052 C CG  . LYS A 1 128 ? 224.695 284.203 246.531 1.00 46.50  ? 385 LYS C CG  1 
ATOM   1053 C CD  . LYS A 1 128 ? 225.262 283.387 245.385 1.00 54.41  ? 385 LYS C CD  1 
ATOM   1054 C CE  . LYS A 1 128 ? 226.728 283.059 245.614 1.00 60.01  ? 385 LYS C CE  1 
ATOM   1055 N NZ  . LYS A 1 128 ? 227.276 282.175 244.547 1.00 54.79  ? 385 LYS C NZ  1 
ATOM   1056 N N   . ASN A 1 129 ? 221.405 285.136 248.354 1.00 56.36  ? 386 ASN C N   1 
ATOM   1057 C CA  . ASN A 1 129 ? 220.529 286.206 247.885 1.00 57.07  ? 386 ASN C CA  1 
ATOM   1058 C C   . ASN A 1 129 ? 219.893 286.838 249.131 1.00 61.26  ? 386 ASN C C   1 
ATOM   1059 O O   . ASN A 1 129 ? 218.681 286.946 249.303 1.00 62.75  ? 386 ASN C O   1 
ATOM   1060 C CB  . ASN A 1 129 ? 219.535 285.620 246.860 1.00 58.76  ? 386 ASN C CB  1 
ATOM   1061 C CG  . ASN A 1 129 ? 218.261 286.462 246.577 1.00 63.42  ? 386 ASN C CG  1 
ATOM   1062 O OD1 . ASN A 1 129 ? 217.941 287.462 247.206 1.00 64.53  ? 386 ASN C OD1 1 
ATOM   1063 N ND2 . ASN A 1 129 ? 217.520 286.005 245.574 1.00 63.86  ? 386 ASN C ND2 1 
ATOM   1064 N N   . VAL A 1 130 ? 220.730 287.081 250.137 1.00 56.32  ? 387 VAL C N   1 
ATOM   1065 C CA  . VAL A 1 130 ? 220.289 287.698 251.384 1.00 49.52  ? 387 VAL C CA  1 
ATOM   1066 C C   . VAL A 1 130 ? 220.325 289.213 251.246 1.00 49.88  ? 387 VAL C C   1 
ATOM   1067 O O   . VAL A 1 130 ? 220.938 289.752 250.319 1.00 51.45  ? 387 VAL C O   1 
ATOM   1068 C CB  . VAL A 1 130 ? 221.151 287.238 252.573 1.00 47.00  ? 387 VAL C CB  1 
ATOM   1069 C CG1 . VAL A 1 130 ? 220.811 285.811 252.952 1.00 39.77  ? 387 VAL C CG1 1 
ATOM   1070 C CG2 . VAL A 1 130 ? 222.625 287.368 252.240 1.00 53.30  ? 387 VAL C CG2 1 
ATOM   1071 N N   . GLN A 1 131 ? 219.669 289.908 252.171 1.00 47.93  ? 388 GLN C N   1 
ATOM   1072 C CA  . GLN A 1 131 ? 219.636 291.366 252.184 1.00 48.90  ? 388 GLN C CA  1 
ATOM   1073 C C   . GLN A 1 131 ? 220.774 291.872 253.062 1.00 48.88  ? 388 GLN C C   1 
ATOM   1074 O O   . GLN A 1 131 ? 220.678 291.844 254.292 1.00 55.39  ? 388 GLN C O   1 
ATOM   1075 C CB  . GLN A 1 131 ? 218.287 291.861 252.697 1.00 46.80  ? 388 GLN C CB  1 
ATOM   1076 C CG  . GLN A 1 131 ? 218.078 293.351 252.576 1.00 45.70  ? 388 GLN C CG  1 
ATOM   1077 C CD  . GLN A 1 131 ? 216.613 293.720 252.568 1.00 50.56  ? 388 GLN C CD  1 
ATOM   1078 O OE1 . GLN A 1 131 ? 215.787 293.032 253.165 1.00 50.44  ? 388 GLN C OE1 1 
ATOM   1079 N NE2 . GLN A 1 131 ? 216.280 294.809 251.888 1.00 51.78  ? 388 GLN C NE2 1 
ATOM   1080 N N   . ARG A 1 132 ? 221.850 292.337 252.433 1.00 48.75  ? 389 ARG C N   1 
ATOM   1081 C CA  . ARG A 1 132 ? 223.020 292.799 253.164 1.00 48.78  ? 389 ARG C CA  1 
ATOM   1082 C C   . ARG A 1 132 ? 222.977 294.284 253.499 1.00 46.88  ? 389 ARG C C   1 
ATOM   1083 O O   . ARG A 1 132 ? 223.844 294.759 254.240 1.00 47.91  ? 389 ARG C O   1 
ATOM   1084 C CB  . ARG A 1 132 ? 224.289 292.491 252.364 1.00 60.96  ? 389 ARG C CB  1 
ATOM   1085 C CG  . ARG A 1 132 ? 224.152 291.297 251.430 1.00 59.13  ? 389 ARG C CG  1 
ATOM   1086 C CD  . ARG A 1 132 ? 225.508 290.725 251.053 1.00 54.36  ? 389 ARG C CD  1 
ATOM   1087 N NE  . ARG A 1 132 ? 225.392 289.581 250.157 1.00 47.39  ? 389 ARG C NE  1 
ATOM   1088 C CZ  . ARG A 1 132 ? 226.351 288.687 249.959 1.00 49.77  ? 389 ARG C CZ  1 
ATOM   1089 N NH1 . ARG A 1 132 ? 227.515 288.775 250.579 1.00 51.59  ? 389 ARG C NH1 1 
ATOM   1090 N NH2 . ARG A 1 132 ? 226.136 287.682 249.116 1.00 53.23  ? 389 ARG C NH2 1 
ATOM   1091 N N   . LYS A 1 133 ? 221.997 295.022 252.988 1.00 56.45  ? 390 LYS C N   1 
ATOM   1092 C CA  . LYS A 1 133 ? 221.865 296.450 253.242 1.00 57.71  ? 390 LYS C CA  1 
ATOM   1093 C C   . LYS A 1 133 ? 220.701 296.683 254.194 1.00 58.16  ? 390 LYS C C   1 
ATOM   1094 O O   . LYS A 1 133 ? 219.625 296.103 254.020 1.00 63.78  ? 390 LYS C O   1 
ATOM   1095 C CB  . LYS A 1 133 ? 221.647 297.224 251.941 1.00 57.14  ? 390 LYS C CB  1 
ATOM   1096 C CG  . LYS A 1 133 ? 222.739 297.019 250.907 1.00 59.93  ? 390 LYS C CG  1 
ATOM   1097 C CD  . LYS A 1 133 ? 223.991 297.798 251.270 1.00 66.40  ? 390 LYS C CD  1 
ATOM   1098 C CE  . LYS A 1 133 ? 225.228 297.187 250.633 1.00 65.25  ? 390 LYS C CE  1 
ATOM   1099 N NZ  . LYS A 1 133 ? 226.421 297.295 251.518 1.00 59.42  ? 390 LYS C NZ  1 
ATOM   1100 N N   . GLY A 1 134 ? 220.918 297.530 255.194 1.00 52.61  ? 391 GLY C N   1 
ATOM   1101 C CA  . GLY A 1 134 ? 219.900 297.765 256.194 1.00 54.56  ? 391 GLY C CA  1 
ATOM   1102 C C   . GLY A 1 134 ? 219.822 296.625 257.193 1.00 49.78  ? 391 GLY C C   1 
ATOM   1103 O O   . GLY A 1 134 ? 220.720 295.784 257.301 1.00 54.38  ? 391 GLY C O   1 
ATOM   1104 N N   . TRP A 1 135 ? 218.724 296.604 257.938 1.00 40.86  ? 392 TRP C N   1 
ATOM   1105 C CA  . TRP A 1 135 ? 218.475 295.560 258.920 1.00 44.51  ? 392 TRP C CA  1 
ATOM   1106 C C   . TRP A 1 135 ? 217.417 294.604 258.394 1.00 53.63  ? 392 TRP C C   1 
ATOM   1107 O O   . TRP A 1 135 ? 216.369 295.036 257.903 1.00 53.18  ? 392 TRP C O   1 
ATOM   1108 C CB  . TRP A 1 135 ? 218.018 296.143 260.256 1.00 46.58  ? 392 TRP C CB  1 
ATOM   1109 C CG  . TRP A 1 135 ? 217.286 295.141 261.090 1.00 42.30  ? 392 TRP C CG  1 
ATOM   1110 C CD1 . TRP A 1 135 ? 217.837 294.170 261.869 1.00 37.85  ? 392 TRP C CD1 1 
ATOM   1111 C CD2 . TRP A 1 135 ? 215.866 294.996 261.214 1.00 47.29  ? 392 TRP C CD2 1 
ATOM   1112 N NE1 . TRP A 1 135 ? 216.851 293.435 262.478 1.00 42.60  ? 392 TRP C NE1 1 
ATOM   1113 C CE2 . TRP A 1 135 ? 215.632 293.922 262.091 1.00 41.35  ? 392 TRP C CE2 1 
ATOM   1114 C CE3 . TRP A 1 135 ? 214.771 295.673 260.670 1.00 53.58  ? 392 TRP C CE3 1 
ATOM   1115 C CZ2 . TRP A 1 135 ? 214.349 293.510 262.441 1.00 36.76  ? 392 TRP C CZ2 1 
ATOM   1116 C CZ3 . TRP A 1 135 ? 213.497 295.260 261.018 1.00 49.54  ? 392 TRP C CZ3 1 
ATOM   1117 C CH2 . TRP A 1 135 ? 213.298 294.189 261.895 1.00 39.87  ? 392 TRP C CH2 1 
ATOM   1118 N N   . VAL A 1 136 ? 217.696 293.309 258.499 1.00 57.13  ? 393 VAL C N   1 
ATOM   1119 C CA  . VAL A 1 136 ? 216.743 292.261 258.161 1.00 50.33  ? 393 VAL C CA  1 
ATOM   1120 C C   . VAL A 1 136 ? 216.811 291.202 259.252 1.00 52.73  ? 393 VAL C C   1 
ATOM   1121 O O   . VAL A 1 136 ? 217.900 290.844 259.714 1.00 58.08  ? 393 VAL C O   1 
ATOM   1122 C CB  . VAL A 1 136 ? 217.027 291.662 256.768 1.00 45.91  ? 393 VAL C CB  1 
ATOM   1123 C CG1 . VAL A 1 136 ? 218.449 291.123 256.692 1.00 44.29  ? 393 VAL C CG1 1 
ATOM   1124 C CG2 . VAL A 1 136 ? 216.015 290.582 256.437 1.00 46.66  ? 393 VAL C CG2 1 
ATOM   1125 N N   . LYS A 1 137 ? 215.648 290.726 259.689 1.00 50.32  ? 394 LYS C N   1 
ATOM   1126 C CA  . LYS A 1 137 ? 215.614 289.748 260.768 1.00 49.46  ? 394 LYS C CA  1 
ATOM   1127 C C   . LYS A 1 137 ? 216.224 288.435 260.299 1.00 51.72  ? 394 LYS C C   1 
ATOM   1128 O O   . LYS A 1 137 ? 215.874 287.921 259.232 1.00 64.45  ? 394 LYS C O   1 
ATOM   1129 C CB  . LYS A 1 137 ? 214.183 289.530 261.252 1.00 51.85  ? 394 LYS C CB  1 
ATOM   1130 C CG  . LYS A 1 137 ? 214.103 288.793 262.578 1.00 56.70  ? 394 LYS C CG  1 
ATOM   1131 C CD  . LYS A 1 137 ? 212.683 288.722 263.105 1.00 50.10  ? 394 LYS C CD  1 
ATOM   1132 C CE  . LYS A 1 137 ? 212.409 289.845 264.085 1.00 47.74  ? 394 LYS C CE  1 
ATOM   1133 N NZ  . LYS A 1 137 ? 211.451 289.433 265.142 1.00 46.29  ? 394 LYS C NZ  1 
ATOM   1134 N N   . MET A 1 138 ? 217.139 287.890 261.099 1.00 39.78  ? 395 MET C N   1 
ATOM   1135 C CA  . MET A 1 138 ? 217.877 286.684 260.725 1.00 44.38  ? 395 MET C CA  1 
ATOM   1136 C C   . MET A 1 138 ? 217.033 285.459 261.065 1.00 46.59  ? 395 MET C C   1 
ATOM   1137 O O   . MET A 1 138 ? 217.254 284.757 262.054 1.00 50.00  ? 395 MET C O   1 
ATOM   1138 C CB  . MET A 1 138 ? 219.229 286.650 261.423 1.00 41.62  ? 395 MET C CB  1 
ATOM   1139 C CG  . MET A 1 138 ? 220.236 287.631 260.857 1.00 46.44  ? 395 MET C CG  1 
ATOM   1140 S SD  . MET A 1 138 ? 221.778 287.648 261.784 1.00 65.62  ? 395 MET C SD  1 
ATOM   1141 C CE  . MET A 1 138 ? 222.186 285.906 261.784 1.00 50.00  ? 395 MET C CE  1 
ATOM   1142 N N   . THR A 1 139 ? 216.048 285.202 260.220 1.00 45.96  ? 396 THR C N   1 
ATOM   1143 C CA  . THR A 1 139 ? 215.166 284.053 260.310 1.00 45.96  ? 396 THR C CA  1 
ATOM   1144 C C   . THR A 1 139 ? 215.445 283.071 259.180 1.00 49.26  ? 396 THR C C   1 
ATOM   1145 O O   . THR A 1 139 ? 216.121 283.405 258.201 1.00 58.01  ? 396 THR C O   1 
ATOM   1146 C CB  . THR A 1 139 ? 213.699 284.502 260.261 1.00 44.83  ? 396 THR C CB  1 
ATOM   1147 O OG1 . THR A 1 139 ? 213.401 285.037 258.967 1.00 47.98  ? 396 THR C OG1 1 
ATOM   1148 C CG2 . THR A 1 139 ? 213.426 285.550 261.314 1.00 47.24  ? 396 THR C CG2 1 
ATOM   1149 N N   . PRO A 1 140 ? 214.958 281.832 259.293 1.00 47.30  ? 397 PRO C N   1 
ATOM   1150 C CA  . PRO A 1 140 ? 215.058 280.910 258.151 1.00 44.79  ? 397 PRO C CA  1 
ATOM   1151 C C   . PRO A 1 140 ? 214.378 281.427 256.897 1.00 55.71  ? 397 PRO C C   1 
ATOM   1152 O O   . PRO A 1 140 ? 214.868 281.175 255.789 1.00 60.70  ? 397 PRO C O   1 
ATOM   1153 C CB  . PRO A 1 140 ? 214.383 279.636 258.673 1.00 44.51  ? 397 PRO C CB  1 
ATOM   1154 C CG  . PRO A 1 140 ? 214.554 279.700 260.139 1.00 52.87  ? 397 PRO C CG  1 
ATOM   1155 C CD  . PRO A 1 140 ? 214.471 281.150 260.505 1.00 58.05  ? 397 PRO C CD  1 
ATOM   1156 N N   . GLU A 1 141 ? 213.260 282.141 257.035 1.00 63.64  ? 398 GLU C N   1 
ATOM   1157 C CA  . GLU A 1 141 ? 212.579 282.690 255.869 1.00 61.82  ? 398 GLU C CA  1 
ATOM   1158 C C   . GLU A 1 141 ? 213.403 283.764 255.176 1.00 59.24  ? 398 GLU C C   1 
ATOM   1159 O O   . GLU A 1 141 ? 213.214 283.996 253.978 1.00 59.83  ? 398 GLU C O   1 
ATOM   1160 C CB  . GLU A 1 141 ? 211.218 283.258 256.268 1.00 61.47  ? 398 GLU C CB  1 
ATOM   1161 C CG  . GLU A 1 141 ? 210.366 282.313 257.096 1.00 63.25  ? 398 GLU C CG  1 
ATOM   1162 C CD  . GLU A 1 141 ? 210.622 282.447 258.583 1.00 70.73  ? 398 GLU C CD  1 
ATOM   1163 O OE1 . GLU A 1 141 ? 210.260 283.494 259.159 1.00 73.57  ? 398 GLU C OE1 1 
ATOM   1164 O OE2 . GLU A 1 141 ? 211.187 281.505 259.177 1.00 69.79  ? 398 GLU C OE2 1 
ATOM   1165 N N   . ASN A 1 142 ? 214.304 284.423 255.896 1.00 55.61  ? 399 ASN C N   1 
ATOM   1166 C CA  . ASN A 1 142 ? 215.179 285.428 255.315 1.00 51.68  ? 399 ASN C CA  1 
ATOM   1167 C C   . ASN A 1 142 ? 216.515 284.854 254.868 1.00 58.22  ? 399 ASN C C   1 
ATOM   1168 O O   . ASN A 1 142 ? 217.367 285.608 254.390 1.00 61.94  ? 399 ASN C O   1 
ATOM   1169 C CB  . ASN A 1 142 ? 215.408 286.563 256.314 1.00 45.98  ? 399 ASN C CB  1 
ATOM   1170 C CG  . ASN A 1 142 ? 214.222 287.497 256.408 1.00 61.60  ? 399 ASN C CG  1 
ATOM   1171 O OD1 . ASN A 1 142 ? 213.445 287.627 255.464 1.00 65.07  ? 399 ASN C OD1 1 
ATOM   1172 N ND2 . ASN A 1 142 ? 214.068 288.143 257.557 1.00 72.32  ? 399 ASN C ND2 1 
ATOM   1173 N N   . GLY A 1 143 ? 216.716 283.547 255.012 1.00 49.25  ? 400 GLY C N   1 
ATOM   1174 C CA  . GLY A 1 143 ? 217.906 282.895 254.517 1.00 47.91  ? 400 GLY C CA  1 
ATOM   1175 C C   . GLY A 1 143 ? 218.988 282.627 255.539 1.00 51.14  ? 400 GLY C C   1 
ATOM   1176 O O   . GLY A 1 143 ? 220.066 282.157 255.158 1.00 60.13  ? 400 GLY C O   1 
ATOM   1177 N N   . PHE A 1 144 ? 218.746 282.902 256.817 1.00 46.95  ? 401 PHE C N   1 
ATOM   1178 C CA  . PHE A 1 144 ? 219.735 282.689 257.868 1.00 46.24  ? 401 PHE C CA  1 
ATOM   1179 C C   . PHE A 1 144 ? 219.299 281.524 258.746 1.00 51.28  ? 401 PHE C C   1 
ATOM   1180 O O   . PHE A 1 144 ? 218.132 281.444 259.142 1.00 53.96  ? 401 PHE C O   1 
ATOM   1181 C CB  . PHE A 1 144 ? 219.918 283.946 258.717 1.00 48.75  ? 401 PHE C CB  1 
ATOM   1182 C CG  . PHE A 1 144 ? 220.317 285.162 257.934 1.00 58.82  ? 401 PHE C CG  1 
ATOM   1183 C CD1 . PHE A 1 144 ? 221.651 285.468 257.741 1.00 58.35  ? 401 PHE C CD1 1 
ATOM   1184 C CD2 . PHE A 1 144 ? 219.359 286.010 257.409 1.00 59.52  ? 401 PHE C CD2 1 
ATOM   1185 C CE1 . PHE A 1 144 ? 222.022 286.589 257.030 1.00 54.38  ? 401 PHE C CE1 1 
ATOM   1186 C CE2 . PHE A 1 144 ? 219.725 287.131 256.695 1.00 53.52  ? 401 PHE C CE2 1 
ATOM   1187 C CZ  . PHE A 1 144 ? 221.057 287.421 256.505 1.00 50.54  ? 401 PHE C CZ  1 
ATOM   1188 N N   . TRP A 1 145 ? 220.236 280.631 259.053 1.00 50.10  ? 402 TRP C N   1 
ATOM   1189 C CA  . TRP A 1 145 ? 220.034 279.546 260.009 1.00 48.41  ? 402 TRP C CA  1 
ATOM   1190 C C   . TRP A 1 145 ? 221.220 279.605 260.966 1.00 55.36  ? 402 TRP C C   1 
ATOM   1191 O O   . TRP A 1 145 ? 222.333 279.209 260.610 1.00 57.55  ? 402 TRP C O   1 
ATOM   1192 C CB  . TRP A 1 145 ? 219.937 278.201 259.296 1.00 47.64  ? 402 TRP C CB  1 
ATOM   1193 C CG  . TRP A 1 145 ? 218.852 278.144 258.262 1.00 52.85  ? 402 TRP C CG  1 
ATOM   1194 C CD1 . TRP A 1 145 ? 217.526 277.917 258.480 1.00 59.48  ? 402 TRP C CD1 1 
ATOM   1195 C CD2 . TRP A 1 145 ? 219.001 278.314 256.848 1.00 49.97  ? 402 TRP C CD2 1 
ATOM   1196 N NE1 . TRP A 1 145 ? 216.840 277.936 257.291 1.00 58.41  ? 402 TRP C NE1 1 
ATOM   1197 C CE2 . TRP A 1 145 ? 217.723 278.177 256.273 1.00 51.77  ? 402 TRP C CE2 1 
ATOM   1198 C CE3 . TRP A 1 145 ? 220.090 278.570 256.011 1.00 48.81  ? 402 TRP C CE3 1 
ATOM   1199 C CZ2 . TRP A 1 145 ? 217.505 278.291 254.905 1.00 44.90  ? 402 TRP C CZ2 1 
ATOM   1200 C CZ3 . TRP A 1 145 ? 219.871 278.679 254.653 1.00 45.03  ? 402 TRP C CZ3 1 
ATOM   1201 C CH2 . TRP A 1 145 ? 218.590 278.540 254.113 1.00 44.89  ? 402 TRP C CH2 1 
ATOM   1202 N N   . THR A 1 146 ? 220.984 280.103 262.179 1.00 55.24  ? 403 THR C N   1 
ATOM   1203 C CA  . THR A 1 146 ? 222.065 280.529 263.056 1.00 50.45  ? 403 THR C CA  1 
ATOM   1204 C C   . THR A 1 146 ? 221.808 280.077 264.489 1.00 56.56  ? 403 THR C C   1 
ATOM   1205 O O   . THR A 1 146 ? 220.666 280.015 264.949 1.00 59.72  ? 403 THR C O   1 
ATOM   1206 C CB  . THR A 1 146 ? 222.225 282.057 263.011 1.00 61.06  ? 403 THR C CB  1 
ATOM   1207 O OG1 . THR A 1 146 ? 221.931 282.530 261.690 1.00 68.82  ? 403 THR C OG1 1 
ATOM   1208 C CG2 . THR A 1 146 ? 223.631 282.477 263.391 1.00 59.49  ? 403 THR C CG2 1 
ATOM   1209 N N   . MET A 1 147 ? 222.897 279.771 265.194 1.00 54.99  ? 404 MET C N   1 
ATOM   1210 C CA  . MET A 1 147 ? 222.863 279.460 266.618 1.00 46.45  ? 404 MET C CA  1 
ATOM   1211 C C   . MET A 1 147 ? 223.560 280.590 267.355 1.00 52.59  ? 404 MET C C   1 
ATOM   1212 O O   . MET A 1 147 ? 224.548 281.132 266.854 1.00 64.16  ? 404 MET C O   1 
ATOM   1213 C CB  . MET A 1 147 ? 223.561 278.132 266.921 1.00 51.86  ? 404 MET C CB  1 
ATOM   1214 C CG  . MET A 1 147 ? 223.539 277.737 268.384 1.00 57.11  ? 404 MET C CG  1 
ATOM   1215 S SD  . MET A 1 147 ? 222.039 276.866 268.832 1.00 61.38  ? 404 MET C SD  1 
ATOM   1216 C CE  . MET A 1 147 ? 221.966 275.683 267.497 1.00 57.52  ? 404 MET C CE  1 
ATOM   1217 N N   . GLY A 1 148 ? 223.067 280.943 268.536 1.00 42.95  ? 405 GLY C N   1 
ATOM   1218 C CA  . GLY A 1 148 ? 223.631 282.118 269.155 1.00 48.78  ? 405 GLY C CA  1 
ATOM   1219 C C   . GLY A 1 148 ? 223.628 282.099 270.666 1.00 46.20  ? 405 GLY C C   1 
ATOM   1220 O O   . GLY A 1 148 ? 222.801 281.445 271.305 1.00 52.91  ? 405 GLY C O   1 
ATOM   1221 N N   . LEU A 1 149 ? 224.568 282.860 271.218 1.00 48.37  ? 406 LEU C N   1 
ATOM   1222 C CA  . LEU A 1 149 ? 224.677 283.126 272.641 1.00 51.06  ? 406 LEU C CA  1 
ATOM   1223 C C   . LEU A 1 149 ? 224.291 284.574 272.906 1.00 52.39  ? 406 LEU C C   1 
ATOM   1224 O O   . LEU A 1 149 ? 224.595 285.468 272.113 1.00 58.33  ? 406 LEU C O   1 
ATOM   1225 C CB  . LEU A 1 149 ? 226.103 282.864 273.137 1.00 56.06  ? 406 LEU C CB  1 
ATOM   1226 C CG  . LEU A 1 149 ? 226.315 282.517 274.609 1.00 50.83  ? 406 LEU C CG  1 
ATOM   1227 C CD1 . LEU A 1 149 ? 227.498 281.582 274.758 1.00 50.62  ? 406 LEU C CD1 1 
ATOM   1228 C CD2 . LEU A 1 149 ? 226.531 283.775 275.414 1.00 51.05  ? 406 LEU C CD2 1 
ATOM   1229 N N   . THR A 1 150 ? 223.616 284.801 274.028 1.00 59.77  ? 407 THR C N   1 
ATOM   1230 C CA  . THR A 1 150 ? 223.081 286.117 274.342 1.00 64.21  ? 407 THR C CA  1 
ATOM   1231 C C   . THR A 1 150 ? 223.144 286.370 275.841 1.00 72.54  ? 407 THR C C   1 
ATOM   1232 O O   . THR A 1 150 ? 222.960 285.449 276.644 1.00 76.19  ? 407 THR C O   1 
ATOM   1233 C CB  . THR A 1 150 ? 221.633 286.261 273.858 1.00 62.56  ? 407 THR C CB  1 
ATOM   1234 O OG1 . THR A 1 150 ? 221.462 285.532 272.638 1.00 56.02  ? 407 THR C OG1 1 
ATOM   1235 C CG2 . THR A 1 150 ? 221.294 287.722 273.618 1.00 63.44  ? 407 THR C CG2 1 
ATOM   1236 N N   . ASP A 1 151 ? 223.395 287.634 276.191 1.00 83.40  ? 408 ASP C N   1 
ATOM   1237 C CA  . ASP A 1 151 ? 223.404 288.150 277.565 1.00 81.97  ? 408 ASP C CA  1 
ATOM   1238 C C   . ASP A 1 151 ? 224.039 287.169 278.547 1.00 77.88  ? 408 ASP C C   1 
ATOM   1239 O O   . ASP A 1 151 ? 223.481 286.841 279.596 1.00 81.60  ? 408 ASP C O   1 
ATOM   1240 C CB  . ASP A 1 151 ? 221.996 288.552 278.017 1.00 83.59  ? 408 ASP C CB  1 
ATOM   1241 C CG  . ASP A 1 151 ? 220.946 287.508 277.692 1.00 88.58  ? 408 ASP C CG  1 
ATOM   1242 O OD1 . ASP A 1 151 ? 220.902 286.472 278.387 1.00 89.77  ? 408 ASP C OD1 1 
ATOM   1243 O OD2 . ASP A 1 151 ? 220.167 287.724 276.740 1.00 85.81  ? 408 ASP C OD2 1 
ATOM   1244 N N   . GLY A 1 152 ? 225.232 286.703 278.195 1.00 57.63  ? 409 GLY C N   1 
ATOM   1245 C CA  . GLY A 1 152 ? 226.015 285.894 279.105 1.00 63.74  ? 409 GLY C CA  1 
ATOM   1246 C C   . GLY A 1 152 ? 225.782 284.400 279.021 1.00 67.16  ? 409 GLY C C   1 
ATOM   1247 O O   . GLY A 1 152 ? 226.665 283.663 278.575 1.00 67.89  ? 409 GLY C O   1 
ATOM   1248 N N   . ASN A 1 153 ? 224.620 283.930 279.465 1.00 64.61  ? 410 ASN C N   1 
ATOM   1249 C CA  . ASN A 1 153 ? 224.351 282.497 279.512 1.00 66.38  ? 410 ASN C CA  1 
ATOM   1250 C C   . ASN A 1 153 ? 222.938 282.226 278.987 1.00 67.65  ? 410 ASN C C   1 
ATOM   1251 O O   . ASN A 1 153 ? 222.119 281.566 279.627 1.00 73.35  ? 410 ASN C O   1 
ATOM   1252 C CB  . ASN A 1 153 ? 224.575 281.963 280.929 1.00 72.36  ? 410 ASN C CB  1 
ATOM   1253 C CG  . ASN A 1 153 ? 224.207 280.493 281.083 1.00 72.51  ? 410 ASN C CG  1 
ATOM   1254 O OD1 . ASN A 1 153 ? 224.077 279.762 280.101 1.00 68.46  ? 410 ASN C OD1 1 
ATOM   1255 N ND2 . ASN A 1 153 ? 224.037 280.056 282.326 1.00 72.71  ? 410 ASN C ND2 1 
ATOM   1256 N N   . LYS A 1 154 ? 222.614 282.788 277.828 1.00 54.97  ? 411 LYS C N   1 
ATOM   1257 C CA  . LYS A 1 154 ? 221.390 282.439 277.122 1.00 55.16  ? 411 LYS C CA  1 
ATOM   1258 C C   . LYS A 1 154 ? 221.746 281.843 275.769 1.00 59.52  ? 411 LYS C C   1 
ATOM   1259 O O   . LYS A 1 154 ? 222.663 282.319 275.099 1.00 65.72  ? 411 LYS C O   1 
ATOM   1260 C CB  . LYS A 1 154 ? 220.482 283.655 276.941 1.00 55.79  ? 411 LYS C CB  1 
ATOM   1261 C CG  . LYS A 1 154 ? 219.005 283.327 276.969 1.00 53.21  ? 411 LYS C CG  1 
ATOM   1262 C CD  . LYS A 1 154 ? 218.172 284.507 276.517 1.00 54.45  ? 411 LYS C CD  1 
ATOM   1263 C CE  . LYS A 1 154 ? 216.946 284.049 275.755 1.00 57.00  ? 411 LYS C CE  1 
ATOM   1264 N NZ  . LYS A 1 154 ? 215.803 284.986 275.923 1.00 62.73  ? 411 LYS C NZ  1 
ATOM   1265 N N   . TYR A 1 155 ? 221.023 280.800 275.369 1.00 50.20  ? 412 TYR C N   1 
ATOM   1266 C CA  . TYR A 1 155 ? 221.254 280.143 274.090 1.00 51.58  ? 412 TYR C CA  1 
ATOM   1267 C C   . TYR A 1 155 ? 219.978 280.172 273.264 1.00 56.15  ? 412 TYR C C   1 
ATOM   1268 O O   . TYR A 1 155 ? 218.892 279.890 273.777 1.00 56.83  ? 412 TYR C O   1 
ATOM   1269 C CB  . TYR A 1 155 ? 221.728 278.705 274.284 1.00 53.10  ? 412 TYR C CB  1 
ATOM   1270 C CG  . TYR A 1 155 ? 223.203 278.610 274.573 1.00 55.68  ? 412 TYR C CG  1 
ATOM   1271 C CD1 . TYR A 1 155 ? 223.715 279.044 275.785 1.00 60.54  ? 412 TYR C CD1 1 
ATOM   1272 C CD2 . TYR A 1 155 ? 224.085 278.099 273.634 1.00 54.00  ? 412 TYR C CD2 1 
ATOM   1273 C CE1 . TYR A 1 155 ? 225.060 278.969 276.059 1.00 62.44  ? 412 TYR C CE1 1 
ATOM   1274 C CE2 . TYR A 1 155 ? 225.436 278.018 273.900 1.00 58.38  ? 412 TYR C CE2 1 
ATOM   1275 C CZ  . TYR A 1 155 ? 225.918 278.456 275.116 1.00 61.63  ? 412 TYR C CZ  1 
ATOM   1276 O OH  . TYR A 1 155 ? 227.262 278.384 275.395 1.00 61.46  ? 412 TYR C OH  1 
ATOM   1277 N N   . ARG A 1 156 ? 220.114 280.512 271.984 1.00 52.27  ? 413 ARG C N   1 
ATOM   1278 C CA  . ARG A 1 156 ? 218.947 280.691 271.134 1.00 47.63  ? 413 ARG C CA  1 
ATOM   1279 C C   . ARG A 1 156 ? 219.207 280.137 269.741 1.00 56.14  ? 413 ARG C C   1 
ATOM   1280 O O   . ARG A 1 156 ? 220.348 280.098 269.267 1.00 59.58  ? 413 ARG C O   1 
ATOM   1281 C CB  . ARG A 1 156 ? 218.555 282.167 271.030 1.00 44.34  ? 413 ARG C CB  1 
ATOM   1282 C CG  . ARG A 1 156 ? 217.823 282.710 272.236 1.00 52.34  ? 413 ARG C CG  1 
ATOM   1283 C CD  . ARG A 1 156 ? 217.625 284.210 272.114 1.00 56.54  ? 413 ARG C CD  1 
ATOM   1284 N NE  . ARG A 1 156 ? 218.884 284.908 271.879 1.00 56.15  ? 413 ARG C NE  1 
ATOM   1285 C CZ  . ARG A 1 156 ? 219.186 285.553 270.761 1.00 54.93  ? 413 ARG C CZ  1 
ATOM   1286 N NH1 . ARG A 1 156 ? 218.341 285.608 269.745 1.00 59.18  ? 413 ARG C NH1 1 
ATOM   1287 N NH2 . ARG A 1 156 ? 220.366 286.156 270.659 1.00 50.52  ? 413 ARG C NH2 1 
ATOM   1288 N N   . THR A 1 157 ? 218.126 279.710 269.095 1.00 60.60  ? 414 THR C N   1 
ATOM   1289 C CA  . THR A 1 157 ? 218.113 279.396 267.673 1.00 57.33  ? 414 THR C CA  1 
ATOM   1290 C C   . THR A 1 157 ? 217.278 280.444 266.956 1.00 59.87  ? 414 THR C C   1 
ATOM   1291 O O   . THR A 1 157 ? 216.105 280.643 267.286 1.00 58.63  ? 414 THR C O   1 
ATOM   1292 C CB  . THR A 1 157 ? 217.539 278.006 267.407 1.00 55.76  ? 414 THR C CB  1 
ATOM   1293 O OG1 . THR A 1 157 ? 216.436 277.765 268.289 1.00 65.00  ? 414 THR C OG1 1 
ATOM   1294 C CG2 . THR A 1 157 ? 218.596 276.948 267.611 1.00 59.07  ? 414 THR C CG2 1 
ATOM   1295 N N   . LEU A 1 158 ? 217.879 281.104 265.969 1.00 58.91  ? 415 LEU C N   1 
ATOM   1296 C CA  . LEU A 1 158 ? 217.261 282.260 265.325 1.00 53.99  ? 415 LEU C CA  1 
ATOM   1297 C C   . LEU A 1 158 ? 216.169 281.829 264.344 1.00 57.22  ? 415 LEU C C   1 
ATOM   1298 O O   . LEU A 1 158 ? 216.278 281.974 263.128 1.00 65.39  ? 415 LEU C O   1 
ATOM   1299 C CB  . LEU A 1 158 ? 218.326 283.105 264.643 1.00 52.61  ? 415 LEU C CB  1 
ATOM   1300 C CG  . LEU A 1 158 ? 219.160 283.940 265.611 1.00 49.27  ? 415 LEU C CG  1 
ATOM   1301 C CD1 . LEU A 1 158 ? 220.450 283.225 265.929 1.00 50.23  ? 415 LEU C CD1 1 
ATOM   1302 C CD2 . LEU A 1 158 ? 219.442 285.307 265.021 1.00 58.25  ? 415 LEU C CD2 1 
ATOM   1303 N N   . THR A 1 159 ? 215.100 281.282 264.908 1.00 53.79  ? 416 THR C N   1 
ATOM   1304 C CA  . THR A 1 159 ? 213.848 281.112 264.191 1.00 48.11  ? 416 THR C CA  1 
ATOM   1305 C C   . THR A 1 159 ? 212.981 282.339 264.456 1.00 53.67  ? 416 THR C C   1 
ATOM   1306 O O   . THR A 1 159 ? 213.448 283.346 264.995 1.00 63.04  ? 416 THR C O   1 
ATOM   1307 C CB  . THR A 1 159 ? 213.157 279.819 264.614 1.00 54.66  ? 416 THR C CB  1 
ATOM   1308 O OG1 . THR A 1 159 ? 212.470 280.030 265.853 1.00 55.76  ? 416 THR C OG1 1 
ATOM   1309 C CG2 . THR A 1 159 ? 214.176 278.708 264.793 1.00 63.74  ? 416 THR C CG2 1 
ATOM   1310 N N   . GLU A 1 160 ? 211.706 282.281 264.081 1.00 62.09  ? 417 GLU C N   1 
ATOM   1311 C CA  . GLU A 1 160 ? 210.759 283.330 264.446 1.00 62.02  ? 417 GLU C CA  1 
ATOM   1312 C C   . GLU A 1 160 ? 209.558 282.730 265.167 1.00 62.58  ? 417 GLU C C   1 
ATOM   1313 O O   . GLU A 1 160 ? 208.912 281.804 264.638 1.00 68.13  ? 417 GLU C O   1 
ATOM   1314 C CB  . GLU A 1 160 ? 210.375 284.182 263.222 1.00 56.11  ? 417 GLU C CB  1 
ATOM   1315 C CG  . GLU A 1 160 ? 209.005 284.007 262.550 1.00 60.76  ? 417 GLU C CG  1 
ATOM   1316 C CD  . GLU A 1 160 ? 208.766 282.629 261.940 1.00 69.59  ? 417 GLU C CD  1 
ATOM   1317 O OE1 . GLU A 1 160 ? 209.581 281.704 262.146 1.00 74.39  ? 417 GLU C OE1 1 
ATOM   1318 O OE2 . GLU A 1 160 ? 207.743 282.471 261.242 1.00 72.54  ? 417 GLU C OE2 1 
ATOM   1319 N N   . PRO A 1 161 ? 209.283 283.137 266.412 1.00 60.72  ? 418 PRO C N   1 
ATOM   1320 C CA  . PRO A 1 161 ? 210.118 283.979 267.281 1.00 60.55  ? 418 PRO C CA  1 
ATOM   1321 C C   . PRO A 1 161 ? 211.290 283.183 267.845 1.00 58.76  ? 418 PRO C C   1 
ATOM   1322 O O   . PRO A 1 161 ? 211.331 281.968 267.685 1.00 60.41  ? 418 PRO C O   1 
ATOM   1323 C CB  . PRO A 1 161 ? 209.135 284.427 268.369 1.00 63.93  ? 418 PRO C CB  1 
ATOM   1324 C CG  . PRO A 1 161 ? 208.149 283.303 268.456 1.00 60.27  ? 418 PRO C CG  1 
ATOM   1325 C CD  . PRO A 1 161 ? 207.992 282.810 267.042 1.00 59.03  ? 418 PRO C CD  1 
ATOM   1326 N N   . ARG A 1 162 ? 212.253 283.839 268.491 1.00 56.28  ? 419 ARG C N   1 
ATOM   1327 C CA  . ARG A 1 162 ? 213.428 283.143 269.000 1.00 56.96  ? 419 ARG C CA  1 
ATOM   1328 C C   . ARG A 1 162 ? 213.031 282.047 269.981 1.00 58.66  ? 419 ARG C C   1 
ATOM   1329 O O   . ARG A 1 162 ? 212.182 282.246 270.854 1.00 63.95  ? 419 ARG C O   1 
ATOM   1330 C CB  . ARG A 1 162 ? 214.377 284.129 269.684 1.00 54.74  ? 419 ARG C CB  1 
ATOM   1331 C CG  . ARG A 1 162 ? 214.720 285.357 268.861 1.00 58.09  ? 419 ARG C CG  1 
ATOM   1332 C CD  . ARG A 1 162 ? 215.567 285.001 267.649 1.00 60.19  ? 419 ARG C CD  1 
ATOM   1333 N NE  . ARG A 1 162 ? 216.464 286.091 267.281 1.00 63.90  ? 419 ARG C NE  1 
ATOM   1334 C CZ  . ARG A 1 162 ? 216.394 286.769 266.144 1.00 60.93  ? 419 ARG C CZ  1 
ATOM   1335 N NH1 . ARG A 1 162 ? 215.483 286.488 265.227 1.00 54.76  ? 419 ARG C NH1 1 
ATOM   1336 N NH2 . ARG A 1 162 ? 217.257 287.756 265.924 1.00 54.79  ? 419 ARG C NH2 1 
ATOM   1337 N N   . THR A 1 163 ? 213.653 280.882 269.832 1.00 57.38  ? 420 THR C N   1 
ATOM   1338 C CA  . THR A 1 163 ? 213.394 279.731 270.682 1.00 54.68  ? 420 THR C CA  1 
ATOM   1339 C C   . THR A 1 163 ? 214.606 279.461 271.561 1.00 55.74  ? 420 THR C C   1 
ATOM   1340 O O   . THR A 1 163 ? 215.750 279.633 271.128 1.00 65.19  ? 420 THR C O   1 
ATOM   1341 C CB  . THR A 1 163 ? 213.072 278.488 269.849 1.00 58.98  ? 420 THR C CB  1 
ATOM   1342 O OG1 . THR A 1 163 ? 214.135 278.246 268.920 1.00 67.61  ? 420 THR C OG1 1 
ATOM   1343 C CG2 . THR A 1 163 ? 211.775 278.684 269.084 1.00 60.13  ? 420 THR C CG2 1 
ATOM   1344 N N   . ASN A 1 164 ? 214.351 279.039 272.795 1.00 41.68  ? 421 ASN C N   1 
ATOM   1345 C CA  . ASN A 1 164 ? 215.422 278.825 273.755 1.00 43.56  ? 421 ASN C CA  1 
ATOM   1346 C C   . ASN A 1 164 ? 215.920 277.389 273.694 1.00 52.32  ? 421 ASN C C   1 
ATOM   1347 O O   . ASN A 1 164 ? 215.130 276.441 273.691 1.00 61.14  ? 421 ASN C O   1 
ATOM   1348 C CB  . ASN A 1 164 ? 214.943 279.146 275.170 1.00 49.34  ? 421 ASN C CB  1 
ATOM   1349 C CG  . ASN A 1 164 ? 214.401 280.553 275.296 1.00 56.33  ? 421 ASN C CG  1 
ATOM   1350 O OD1 . ASN A 1 164 ? 215.060 281.435 275.842 1.00 54.52  ? 421 ASN C OD1 1 
ATOM   1351 N ND2 . ASN A 1 164 ? 213.190 280.769 274.798 1.00 59.62  ? 421 ASN C ND2 1 
ATOM   1352 N N   . LEU A 1 165 ? 217.240 277.231 273.645 1.00 52.78  ? 422 LEU C N   1 
ATOM   1353 C CA  . LEU A 1 165 ? 217.878 275.921 273.655 1.00 54.77  ? 422 LEU C CA  1 
ATOM   1354 C C   . LEU A 1 165 ? 218.481 275.683 275.032 1.00 57.81  ? 422 LEU C C   1 
ATOM   1355 O O   . LEU A 1 165 ? 219.561 276.196 275.342 1.00 60.66  ? 422 LEU C O   1 
ATOM   1356 C CB  . LEU A 1 165 ? 218.945 275.811 272.571 1.00 50.81  ? 422 LEU C CB  1 
ATOM   1357 C CG  . LEU A 1 165 ? 218.432 275.526 271.164 1.00 52.58  ? 422 LEU C CG  1 
ATOM   1358 C CD1 . LEU A 1 165 ? 219.534 274.884 270.351 1.00 59.08  ? 422 LEU C CD1 1 
ATOM   1359 C CD2 . LEU A 1 165 ? 217.198 274.641 271.199 1.00 55.53  ? 422 LEU C CD2 1 
ATOM   1360 N N   . LYS A 1 166 ? 217.782 274.904 275.851 1.00 53.28  ? 423 LYS C N   1 
ATOM   1361 C CA  . LYS A 1 166 ? 218.270 274.516 277.168 1.00 47.70  ? 423 LYS C CA  1 
ATOM   1362 C C   . LYS A 1 166 ? 219.289 273.401 276.985 1.00 49.81  ? 423 LYS C C   1 
ATOM   1363 O O   . LYS A 1 166 ? 218.968 272.341 276.438 1.00 52.28  ? 423 LYS C O   1 
ATOM   1364 C CB  . LYS A 1 166 ? 217.113 274.063 278.053 1.00 50.19  ? 423 LYS C CB  1 
ATOM   1365 C CG  . LYS A 1 166 ? 215.893 274.955 277.966 1.00 52.60  ? 423 LYS C CG  1 
ATOM   1366 C CD  . LYS A 1 166 ? 214.627 274.164 278.219 1.00 54.39  ? 423 LYS C CD  1 
ATOM   1367 C CE  . LYS A 1 166 ? 214.369 273.186 277.089 1.00 52.30  ? 423 LYS C CE  1 
ATOM   1368 N NZ  . LYS A 1 166 ? 214.537 273.829 275.759 1.00 52.31  ? 423 LYS C NZ  1 
ATOM   1369 N N   . LEU A 1 167 ? 220.515 273.634 277.435 1.00 52.24  ? 424 LEU C N   1 
ATOM   1370 C CA  . LEU A 1 167 ? 221.551 272.623 277.324 1.00 57.63  ? 424 LEU C CA  1 
ATOM   1371 C C   . LEU A 1 167 ? 222.267 272.463 278.656 1.00 55.53  ? 424 LEU C C   1 
ATOM   1372 O O   . LEU A 1 167 ? 222.373 273.420 279.429 1.00 57.63  ? 424 LEU C O   1 
ATOM   1373 C CB  . LEU A 1 167 ? 222.558 272.982 276.222 1.00 57.53  ? 424 LEU C CB  1 
ATOM   1374 C CG  . LEU A 1 167 ? 223.752 273.862 276.586 1.00 58.19  ? 424 LEU C CG  1 
ATOM   1375 C CD1 . LEU A 1 167 ? 224.813 273.771 275.507 1.00 58.55  ? 424 LEU C CD1 1 
ATOM   1376 C CD2 . LEU A 1 167 ? 223.325 275.304 276.802 1.00 56.29  ? 424 LEU C CD2 1 
ATOM   1377 N N   . PRO A 1 168 ? 222.754 271.259 278.957 1.00 52.01  ? 425 PRO C N   1 
ATOM   1378 C CA  . PRO A 1 168 ? 223.382 271.026 280.264 1.00 55.41  ? 425 PRO C CA  1 
ATOM   1379 C C   . PRO A 1 168 ? 224.821 271.511 280.346 1.00 58.62  ? 425 PRO C C   1 
ATOM   1380 O O   . PRO A 1 168 ? 225.287 271.896 281.422 1.00 60.90  ? 425 PRO C O   1 
ATOM   1381 C CB  . PRO A 1 168 ? 223.301 269.503 280.416 1.00 53.48  ? 425 PRO C CB  1 
ATOM   1382 C CG  . PRO A 1 168 ? 223.316 268.995 279.020 1.00 50.28  ? 425 PRO C CG  1 
ATOM   1383 C CD  . PRO A 1 168 ? 222.590 270.013 278.190 1.00 47.86  ? 425 PRO C CD  1 
ATOM   1384 N N   . LYS A 1 169 ? 225.532 271.498 279.227 1.00 53.97  ? 426 LYS C N   1 
ATOM   1385 C CA  . LYS A 1 169 ? 226.943 271.839 279.202 1.00 51.39  ? 426 LYS C CA  1 
ATOM   1386 C C   . LYS A 1 169 ? 227.136 273.266 278.692 1.00 53.50  ? 426 LYS C C   1 
ATOM   1387 O O   . LYS A 1 169 ? 226.181 274.028 278.525 1.00 53.05  ? 426 LYS C O   1 
ATOM   1388 C CB  . LYS A 1 169 ? 227.703 270.819 278.355 1.00 51.77  ? 426 LYS C CB  1 
ATOM   1389 C CG  . LYS A 1 169 ? 228.404 269.750 279.175 1.00 55.88  ? 426 LYS C CG  1 
ATOM   1390 C CD  . LYS A 1 169 ? 229.077 268.713 278.293 1.00 62.06  ? 426 LYS C CD  1 
ATOM   1391 C CE  . LYS A 1 169 ? 228.209 268.334 277.103 1.00 61.07  ? 426 LYS C CE  1 
ATOM   1392 N NZ  . LYS A 1 169 ? 226.865 267.836 277.513 1.00 62.37  ? 426 LYS C NZ  1 
ATOM   1393 N N   . THR A 1 170 ? 228.388 273.644 278.466 1.00 54.90  ? 427 THR C N   1 
ATOM   1394 C CA  . THR A 1 170 ? 228.729 274.959 277.926 1.00 57.50  ? 427 THR C CA  1 
ATOM   1395 C C   . THR A 1 170 ? 229.736 274.771 276.802 1.00 56.99  ? 427 THR C C   1 
ATOM   1396 O O   . THR A 1 170 ? 230.921 274.490 277.077 1.00 56.23  ? 427 THR C O   1 
ATOM   1397 C CB  . THR A 1 170 ? 229.286 275.875 279.011 1.00 61.60  ? 427 THR C CB  1 
ATOM   1398 O OG1 . THR A 1 170 ? 228.257 276.161 279.967 1.00 63.50  ? 427 THR C OG1 1 
ATOM   1399 C CG2 . THR A 1 170 ? 229.778 277.181 278.404 1.00 60.20  ? 427 THR C CG2 1 
ATOM   1400 N N   . PRO A 1 171 ? 229.323 274.900 275.544 1.00 55.32  ? 428 PRO C N   1 
ATOM   1401 C CA  . PRO A 1 171 ? 230.241 274.629 274.436 1.00 55.51  ? 428 PRO C CA  1 
ATOM   1402 C C   . PRO A 1 171 ? 231.368 275.644 274.355 1.00 53.84  ? 428 PRO C C   1 
ATOM   1403 O O   . PRO A 1 171 ? 231.221 276.812 274.721 1.00 54.28  ? 428 PRO C O   1 
ATOM   1404 C CB  . PRO A 1 171 ? 229.337 274.711 273.201 1.00 53.66  ? 428 PRO C CB  1 
ATOM   1405 C CG  . PRO A 1 171 ? 228.236 275.616 273.613 1.00 52.98  ? 428 PRO C CG  1 
ATOM   1406 C CD  . PRO A 1 171 ? 228.000 275.333 275.069 1.00 55.35  ? 428 PRO C CD  1 
ATOM   1407 N N   . LYS A 1 172 ? 232.505 275.173 273.868 1.00 58.45  ? 429 LYS C N   1 
ATOM   1408 C CA  . LYS A 1 172 ? 233.635 276.020 273.517 1.00 61.20  ? 429 LYS C CA  1 
ATOM   1409 C C   . LYS A 1 172 ? 234.001 275.909 272.048 1.00 66.44  ? 429 LYS C C   1 
ATOM   1410 O O   . LYS A 1 172 ? 234.343 276.915 271.421 1.00 71.36  ? 429 LYS C O   1 
ATOM   1411 C CB  . LYS A 1 172 ? 234.849 275.669 274.389 1.00 59.49  ? 429 LYS C CB  1 
ATOM   1412 C CG  . LYS A 1 172 ? 236.196 275.919 273.735 1.00 61.19  ? 429 LYS C CG  1 
ATOM   1413 C CD  . LYS A 1 172 ? 237.336 275.577 274.677 1.00 64.23  ? 429 LYS C CD  1 
ATOM   1414 C CE  . LYS A 1 172 ? 237.137 276.212 276.043 1.00 67.60  ? 429 LYS C CE  1 
ATOM   1415 N NZ  . LYS A 1 172 ? 236.985 277.689 275.955 1.00 70.39  ? 429 LYS C NZ  1 
ATOM   1416 N N   . LYS A 1 173 ? 233.917 274.712 271.478 1.00 51.57  ? 430 LYS C N   1 
ATOM   1417 C CA  . LYS A 1 173 ? 234.127 274.488 270.056 1.00 52.22  ? 430 LYS C CA  1 
ATOM   1418 C C   . LYS A 1 173 ? 232.861 273.884 269.472 1.00 49.90  ? 430 LYS C C   1 
ATOM   1419 O O   . LYS A 1 173 ? 232.375 272.861 269.964 1.00 55.80  ? 430 LYS C O   1 
ATOM   1420 C CB  . LYS A 1 173 ? 235.322 273.565 269.811 1.00 50.94  ? 430 LYS C CB  1 
ATOM   1421 C CG  . LYS A 1 173 ? 235.961 273.717 268.446 1.00 48.94  ? 430 LYS C CG  1 
ATOM   1422 C CD  . LYS A 1 173 ? 236.909 272.569 268.157 1.00 48.64  ? 430 LYS C CD  1 
ATOM   1423 C CE  . LYS A 1 173 ? 237.933 272.414 269.263 1.00 52.68  ? 430 LYS C CE  1 
ATOM   1424 N NZ  . LYS A 1 173 ? 238.577 271.076 269.229 1.00 57.27  ? 430 LYS C NZ  1 
ATOM   1425 N N   . VAL A 1 174 ? 232.329 274.516 268.432 1.00 44.42  ? 431 VAL C N   1 
ATOM   1426 C CA  . VAL A 1 174 ? 231.096 274.089 267.790 1.00 48.23  ? 431 VAL C CA  1 
ATOM   1427 C C   . VAL A 1 174 ? 231.421 273.692 266.359 1.00 51.04  ? 431 VAL C C   1 
ATOM   1428 O O   . VAL A 1 174 ? 232.053 274.458 265.623 1.00 60.12  ? 431 VAL C O   1 
ATOM   1429 C CB  . VAL A 1 174 ? 230.024 275.194 267.821 1.00 53.10  ? 431 VAL C CB  1 
ATOM   1430 C CG1 . VAL A 1 174 ? 228.669 274.630 267.441 1.00 51.39  ? 431 VAL C CG1 1 
ATOM   1431 C CG2 . VAL A 1 174 ? 229.968 275.839 269.192 1.00 54.14  ? 431 VAL C CG2 1 
ATOM   1432 N N   . GLY A 1 175 ? 231.003 272.495 265.976 1.00 47.86  ? 432 GLY C N   1 
ATOM   1433 C CA  . GLY A 1 175 ? 231.116 272.026 264.606 1.00 50.99  ? 432 GLY C CA  1 
ATOM   1434 C C   . GLY A 1 175 ? 229.785 272.211 263.899 1.00 54.94  ? 432 GLY C C   1 
ATOM   1435 O O   . GLY A 1 175 ? 228.738 271.798 264.409 1.00 58.48  ? 432 GLY C O   1 
ATOM   1436 N N   . VAL A 1 176 ? 229.833 272.846 262.733 1.00 42.16  ? 433 VAL C N   1 
ATOM   1437 C CA  . VAL A 1 176 ? 228.658 273.065 261.901 1.00 40.06  ? 433 VAL C CA  1 
ATOM   1438 C C   . VAL A 1 176 ? 228.728 272.095 260.734 1.00 52.31  ? 433 VAL C C   1 
ATOM   1439 O O   . VAL A 1 176 ? 229.757 272.012 260.048 1.00 63.00  ? 433 VAL C O   1 
ATOM   1440 C CB  . VAL A 1 176 ? 228.571 274.519 261.410 1.00 47.09  ? 433 VAL C CB  1 
ATOM   1441 C CG1 . VAL A 1 176 ? 227.246 274.757 260.707 1.00 48.96  ? 433 VAL C CG1 1 
ATOM   1442 C CG2 . VAL A 1 176 ? 228.742 275.475 262.572 1.00 49.30  ? 433 VAL C CG2 1 
ATOM   1443 N N   . PHE A 1 177 ? 227.640 271.358 260.518 1.00 54.50  ? 434 PHE C N   1 
ATOM   1444 C CA  . PHE A 1 177 ? 227.569 270.314 259.504 1.00 57.50  ? 434 PHE C CA  1 
ATOM   1445 C C   . PHE A 1 177 ? 226.418 270.626 258.562 1.00 52.44  ? 434 PHE C C   1 
ATOM   1446 O O   . PHE A 1 177 ? 225.272 270.754 259.004 1.00 55.36  ? 434 PHE C O   1 
ATOM   1447 C CB  . PHE A 1 177 ? 227.374 268.942 260.154 1.00 49.13  ? 434 PHE C CB  1 
ATOM   1448 C CG  . PHE A 1 177 ? 228.397 268.620 261.201 1.00 43.43  ? 434 PHE C CG  1 
ATOM   1449 C CD1 . PHE A 1 177 ? 228.231 269.042 262.506 1.00 53.26  ? 434 PHE C CD1 1 
ATOM   1450 C CD2 . PHE A 1 177 ? 229.527 267.898 260.880 1.00 47.18  ? 434 PHE C CD2 1 
ATOM   1451 C CE1 . PHE A 1 177 ? 229.177 268.752 263.465 1.00 56.61  ? 434 PHE C CE1 1 
ATOM   1452 C CE2 . PHE A 1 177 ? 230.475 267.604 261.833 1.00 55.78  ? 434 PHE C CE2 1 
ATOM   1453 C CZ  . PHE A 1 177 ? 230.299 268.030 263.128 1.00 55.44  ? 434 PHE C CZ  1 
ATOM   1454 N N   . LEU A 1 178 ? 226.718 270.745 257.273 1.00 50.40  ? 435 LEU C N   1 
ATOM   1455 C CA  . LEU A 1 178 ? 225.724 271.065 256.260 1.00 55.72  ? 435 LEU C CA  1 
ATOM   1456 C C   . LEU A 1 178 ? 225.581 269.899 255.295 1.00 56.40  ? 435 LEU C C   1 
ATOM   1457 O O   . LEU A 1 178 ? 226.574 269.433 254.725 1.00 62.36  ? 435 LEU C O   1 
ATOM   1458 C CB  . LEU A 1 178 ? 226.106 272.332 255.493 1.00 62.70  ? 435 LEU C CB  1 
ATOM   1459 C CG  . LEU A 1 178 ? 225.288 272.615 254.231 1.00 61.58  ? 435 LEU C CG  1 
ATOM   1460 C CD1 . LEU A 1 178 ? 223.817 272.784 254.566 1.00 63.14  ? 435 LEU C CD1 1 
ATOM   1461 C CD2 . LEU A 1 178 ? 225.818 273.841 253.510 1.00 61.08  ? 435 LEU C CD2 1 
ATOM   1462 N N   . ASP A 1 179 ? 224.346 269.433 255.120 1.00 61.71  ? 436 ASP C N   1 
ATOM   1463 C CA  . ASP A 1 179 ? 223.994 268.418 254.134 1.00 66.05  ? 436 ASP C CA  1 
ATOM   1464 C C   . ASP A 1 179 ? 222.975 269.037 253.188 1.00 65.53  ? 436 ASP C C   1 
ATOM   1465 O O   . ASP A 1 179 ? 221.821 269.266 253.575 1.00 66.92  ? 436 ASP C O   1 
ATOM   1466 C CB  . ASP A 1 179 ? 223.432 267.164 254.804 1.00 70.55  ? 436 ASP C CB  1 
ATOM   1467 C CG  . ASP A 1 179 ? 224.444 266.469 255.694 1.00 72.10  ? 436 ASP C CG  1 
ATOM   1468 O OD1 . ASP A 1 179 ? 225.555 267.008 255.863 1.00 73.89  ? 436 ASP C OD1 1 
ATOM   1469 O OD2 . ASP A 1 179 ? 224.130 265.385 256.226 1.00 64.65  ? 436 ASP C OD2 1 
ATOM   1470 N N   . TYR A 1 180 ? 223.409 269.319 251.957 1.00 67.70  ? 437 TYR C N   1 
ATOM   1471 C CA  . TYR A 1 180 ? 222.537 269.955 250.973 1.00 72.20  ? 437 TYR C CA  1 
ATOM   1472 C C   . TYR A 1 180 ? 221.348 269.069 250.627 1.00 74.30  ? 437 TYR C C   1 
ATOM   1473 O O   . TYR A 1 180 ? 220.192 269.504 250.689 1.00 67.52  ? 437 TYR C O   1 
ATOM   1474 C CB  . TYR A 1 180 ? 223.325 270.269 249.703 1.00 71.34  ? 437 TYR C CB  1 
ATOM   1475 C CG  . TYR A 1 180 ? 222.730 271.379 248.870 1.00 72.32  ? 437 TYR C CG  1 
ATOM   1476 C CD1 . TYR A 1 180 ? 222.430 272.611 249.427 1.00 64.27  ? 437 TYR C CD1 1 
ATOM   1477 C CD2 . TYR A 1 180 ? 222.506 271.205 247.512 1.00 70.06  ? 437 TYR C CD2 1 
ATOM   1478 C CE1 . TYR A 1 180 ? 221.903 273.625 248.662 1.00 62.80  ? 437 TYR C CE1 1 
ATOM   1479 C CE2 . TYR A 1 180 ? 221.967 272.211 246.743 1.00 68.70  ? 437 TYR C CE2 1 
ATOM   1480 C CZ  . TYR A 1 180 ? 221.672 273.422 247.323 1.00 69.39  ? 437 TYR C CZ  1 
ATOM   1481 O OH  . TYR A 1 180 ? 221.141 274.436 246.561 1.00 76.42  ? 437 TYR C OH  1 
ATOM   1482 N N   . GLU A 1 181 ? 221.619 267.822 250.244 1.00 72.19  ? 438 GLU C N   1 
ATOM   1483 C CA  . GLU A 1 181 ? 220.568 266.952 249.731 1.00 68.53  ? 438 GLU C CA  1 
ATOM   1484 C C   . GLU A 1 181 ? 219.560 266.608 250.817 1.00 66.95  ? 438 GLU C C   1 
ATOM   1485 O O   . GLU A 1 181 ? 218.348 266.759 250.623 1.00 67.32  ? 438 GLU C O   1 
ATOM   1486 C CB  . GLU A 1 181 ? 221.190 265.686 249.142 1.00 70.91  ? 438 GLU C CB  1 
ATOM   1487 C CG  . GLU A 1 181 ? 222.163 265.939 247.993 1.00 70.75  ? 438 GLU C CG  1 
ATOM   1488 C CD  . GLU A 1 181 ? 223.542 266.382 248.456 1.00 70.86  ? 438 GLU C CD  1 
ATOM   1489 O OE1 . GLU A 1 181 ? 223.711 266.676 249.658 1.00 63.46  ? 438 GLU C OE1 1 
ATOM   1490 O OE2 . GLU A 1 181 ? 224.460 266.437 247.613 1.00 77.51  ? 438 GLU C OE2 1 
ATOM   1491 N N   . THR A 1 182 ? 220.042 266.156 251.975 1.00 53.65  ? 439 THR C N   1 
ATOM   1492 C CA  . THR A 1 182 ? 219.135 265.857 253.077 1.00 57.21  ? 439 THR C CA  1 
ATOM   1493 C C   . THR A 1 182 ? 218.573 267.135 253.682 1.00 62.36  ? 439 THR C C   1 
ATOM   1494 O O   . THR A 1 182 ? 217.588 267.095 254.428 1.00 62.19  ? 439 THR C O   1 
ATOM   1495 C CB  . THR A 1 182 ? 219.852 265.029 254.142 1.00 58.52  ? 439 THR C CB  1 
ATOM   1496 O OG1 . THR A 1 182 ? 220.553 265.902 255.033 1.00 67.59  ? 439 THR C OG1 1 
ATOM   1497 C CG2 . THR A 1 182 ? 220.846 264.083 253.494 1.00 56.41  ? 439 THR C CG2 1 
ATOM   1498 N N   . GLY A 1 183 ? 219.179 268.277 253.365 1.00 61.57  ? 440 GLY C N   1 
ATOM   1499 C CA  . GLY A 1 183 ? 218.715 269.551 253.873 1.00 62.95  ? 440 GLY C CA  1 
ATOM   1500 C C   . GLY A 1 183 ? 218.841 269.668 255.376 1.00 57.96  ? 440 GLY C C   1 
ATOM   1501 O O   . GLY A 1 183 ? 217.874 270.024 256.056 1.00 51.85  ? 440 GLY C O   1 
ATOM   1502 N N   . ASP A 1 184 ? 220.020 269.363 255.912 1.00 61.22  ? 441 ASP C N   1 
ATOM   1503 C CA  . ASP A 1 184 ? 220.210 269.335 257.355 1.00 64.46  ? 441 ASP C CA  1 
ATOM   1504 C C   . ASP A 1 184 ? 221.410 270.180 257.752 1.00 63.95  ? 441 ASP C C   1 
ATOM   1505 O O   . ASP A 1 184 ? 222.530 269.928 257.301 1.00 59.31  ? 441 ASP C O   1 
ATOM   1506 C CB  . ASP A 1 184 ? 220.389 267.899 257.856 1.00 72.07  ? 441 ASP C CB  1 
ATOM   1507 C CG  . ASP A 1 184 ? 219.099 267.104 257.810 1.00 75.34  ? 441 ASP C CG  1 
ATOM   1508 O OD1 . ASP A 1 184 ? 218.017 267.718 257.921 1.00 72.31  ? 441 ASP C OD1 1 
ATOM   1509 O OD2 . ASP A 1 184 ? 219.168 265.865 257.663 1.00 70.16  ? 441 ASP C OD2 1 
ATOM   1510 N N   . ILE A 1 185 ? 221.171 271.174 258.602 1.00 57.75  ? 442 ILE C N   1 
ATOM   1511 C CA  . ILE A 1 185 ? 222.227 271.953 259.236 1.00 54.65  ? 442 ILE C CA  1 
ATOM   1512 C C   . ILE A 1 185 ? 222.240 271.569 260.706 1.00 51.17  ? 442 ILE C C   1 
ATOM   1513 O O   . ILE A 1 185 ? 221.229 271.727 261.400 1.00 56.98  ? 442 ILE C O   1 
ATOM   1514 C CB  . ILE A 1 185 ? 222.014 273.465 259.067 1.00 56.08  ? 442 ILE C CB  1 
ATOM   1515 C CG1 . ILE A 1 185 ? 221.757 273.811 257.602 1.00 53.74  ? 442 ILE C CG1 1 
ATOM   1516 C CG2 . ILE A 1 185 ? 223.217 274.230 259.586 1.00 56.58  ? 442 ILE C CG2 1 
ATOM   1517 C CD1 . ILE A 1 185 ? 220.833 274.984 257.414 1.00 54.53  ? 442 ILE C CD1 1 
ATOM   1518 N N   . SER A 1 186 ? 223.374 271.066 261.176 1.00 51.40  ? 443 SER C N   1 
ATOM   1519 C CA  . SER A 1 186 ? 223.495 270.536 262.526 1.00 52.26  ? 443 SER C CA  1 
ATOM   1520 C C   . SER A 1 186 ? 224.625 271.233 263.267 1.00 57.47  ? 443 SER C C   1 
ATOM   1521 O O   . SER A 1 186 ? 225.692 271.487 262.697 1.00 67.52  ? 443 SER C O   1 
ATOM   1522 C CB  . SER A 1 186 ? 223.749 269.026 262.501 1.00 56.88  ? 443 SER C CB  1 
ATOM   1523 O OG  . SER A 1 186 ? 223.001 268.402 261.473 1.00 65.67  ? 443 SER C OG  1 
ATOM   1524 N N   . PHE A 1 187 ? 224.388 271.536 264.541 1.00 36.00  ? 444 PHE C N   1 
ATOM   1525 C CA  . PHE A 1 187 ? 225.405 272.114 265.409 1.00 32.39  ? 444 PHE C CA  1 
ATOM   1526 C C   . PHE A 1 187 ? 225.776 271.105 266.486 1.00 38.78  ? 444 PHE C C   1 
ATOM   1527 O O   . PHE A 1 187 ? 224.903 270.624 267.216 1.00 49.27  ? 444 PHE C O   1 
ATOM   1528 C CB  . PHE A 1 187 ? 224.912 273.415 266.048 1.00 39.98  ? 444 PHE C CB  1 
ATOM   1529 C CG  . PHE A 1 187 ? 224.629 274.509 265.060 1.00 43.94  ? 444 PHE C CG  1 
ATOM   1530 C CD1 . PHE A 1 187 ? 223.383 274.622 264.467 1.00 46.00  ? 444 PHE C CD1 1 
ATOM   1531 C CD2 . PHE A 1 187 ? 225.606 275.431 264.731 1.00 40.82  ? 444 PHE C CD2 1 
ATOM   1532 C CE1 . PHE A 1 187 ? 223.120 275.628 263.561 1.00 37.76  ? 444 PHE C CE1 1 
ATOM   1533 C CE2 . PHE A 1 187 ? 225.349 276.437 263.826 1.00 39.36  ? 444 PHE C CE2 1 
ATOM   1534 C CZ  . PHE A 1 187 ? 224.105 276.535 263.240 1.00 41.88  ? 444 PHE C CZ  1 
ATOM   1535 N N   . TYR A 1 188 ? 227.066 270.791 266.590 1.00 40.84  ? 445 TYR C N   1 
ATOM   1536 C CA  . TYR A 1 188 ? 227.552 269.799 267.538 1.00 47.84  ? 445 TYR C CA  1 
ATOM   1537 C C   . TYR A 1 188 ? 228.633 270.406 268.418 1.00 48.88  ? 445 TYR C C   1 
ATOM   1538 O O   . TYR A 1 188 ? 229.333 271.337 268.016 1.00 52.46  ? 445 TYR C O   1 
ATOM   1539 C CB  . TYR A 1 188 ? 228.120 268.560 266.827 1.00 49.05  ? 445 TYR C CB  1 
ATOM   1540 C CG  . TYR A 1 188 ? 227.075 267.608 266.296 1.00 45.84  ? 445 TYR C CG  1 
ATOM   1541 C CD1 . TYR A 1 188 ? 225.743 267.736 266.655 1.00 49.16  ? 445 TYR C CD1 1 
ATOM   1542 C CD2 . TYR A 1 188 ? 227.420 266.584 265.431 1.00 40.16  ? 445 TYR C CD2 1 
ATOM   1543 C CE1 . TYR A 1 188 ? 224.788 266.872 266.169 1.00 46.20  ? 445 TYR C CE1 1 
ATOM   1544 C CE2 . TYR A 1 188 ? 226.469 265.718 264.939 1.00 45.38  ? 445 TYR C CE2 1 
ATOM   1545 C CZ  . TYR A 1 188 ? 225.157 265.865 265.312 1.00 45.59  ? 445 TYR C CZ  1 
ATOM   1546 O OH  . TYR A 1 188 ? 224.209 264.998 264.823 1.00 50.74  ? 445 TYR C OH  1 
ATOM   1547 N N   . ASN A 1 189 ? 228.768 269.863 269.623 1.00 47.45  ? 446 ASN C N   1 
ATOM   1548 C CA  . ASN A 1 189 ? 229.826 270.272 270.543 1.00 51.80  ? 446 ASN C CA  1 
ATOM   1549 C C   . ASN A 1 189 ? 231.060 269.434 270.237 1.00 54.85  ? 446 ASN C C   1 
ATOM   1550 O O   . ASN A 1 189 ? 231.138 268.263 270.612 1.00 59.40  ? 446 ASN C O   1 
ATOM   1551 C CB  . ASN A 1 189 ? 229.375 270.100 271.988 1.00 49.40  ? 446 ASN C CB  1 
ATOM   1552 C CG  . ASN A 1 189 ? 230.338 270.717 272.976 1.00 48.96  ? 446 ASN C CG  1 
ATOM   1553 O OD1 . ASN A 1 189 ? 231.316 271.354 272.592 1.00 53.86  ? 446 ASN C OD1 1 
ATOM   1554 N ND2 . ASN A 1 189 ? 230.064 270.530 274.259 1.00 45.04  ? 446 ASN C ND2 1 
ATOM   1555 N N   . ALA A 1 190 ? 232.032 270.035 269.552 1.00 56.99  ? 447 ALA C N   1 
ATOM   1556 C CA  . ALA A 1 190 ? 233.198 269.302 269.069 1.00 52.23  ? 447 ALA C CA  1 
ATOM   1557 C C   . ALA A 1 190 ? 234.063 268.740 270.187 1.00 54.49  ? 447 ALA C C   1 
ATOM   1558 O O   . ALA A 1 190 ? 234.798 267.778 269.943 1.00 56.68  ? 447 ALA C O   1 
ATOM   1559 C CB  . ALA A 1 190 ? 234.046 270.201 268.169 1.00 54.76  ? 447 ALA C CB  1 
ATOM   1560 N N   . VAL A 1 191 ? 234.007 269.307 271.387 1.00 52.33  ? 448 VAL C N   1 
ATOM   1561 C CA  . VAL A 1 191 ? 234.805 268.801 272.498 1.00 51.55  ? 448 VAL C CA  1 
ATOM   1562 C C   . VAL A 1 191 ? 234.294 267.450 272.983 1.00 48.12  ? 448 VAL C C   1 
ATOM   1563 O O   . VAL A 1 191 ? 235.083 266.537 273.234 1.00 52.16  ? 448 VAL C O   1 
ATOM   1564 C CB  . VAL A 1 191 ? 234.831 269.839 273.637 1.00 53.94  ? 448 VAL C CB  1 
ATOM   1565 C CG1 . VAL A 1 191 ? 235.304 269.202 274.933 1.00 53.75  ? 448 VAL C CG1 1 
ATOM   1566 C CG2 . VAL A 1 191 ? 235.720 271.012 273.261 1.00 52.78  ? 448 VAL C CG2 1 
ATOM   1567 N N   . ASP A 1 192 ? 232.978 267.293 273.113 1.00 52.90  ? 449 ASP C N   1 
ATOM   1568 C CA  . ASP A 1 192 ? 232.398 266.081 273.674 1.00 60.33  ? 449 ASP C CA  1 
ATOM   1569 C C   . ASP A 1 192 ? 231.559 265.280 272.692 1.00 56.07  ? 449 ASP C C   1 
ATOM   1570 O O   . ASP A 1 192 ? 231.491 264.057 272.820 1.00 64.09  ? 449 ASP C O   1 
ATOM   1571 C CB  . ASP A 1 192 ? 231.541 266.424 274.900 1.00 65.28  ? 449 ASP C CB  1 
ATOM   1572 C CG  . ASP A 1 192 ? 230.121 266.804 274.535 1.00 68.87  ? 449 ASP C CG  1 
ATOM   1573 O OD1 . ASP A 1 192 ? 229.277 265.897 274.377 1.00 67.20  ? 449 ASP C OD1 1 
ATOM   1574 O OD2 . ASP A 1 192 ? 229.843 268.016 274.430 1.00 71.41  ? 449 ASP C OD2 1 
ATOM   1575 N N   . GLY A 1 193 ? 230.917 265.924 271.725 1.00 49.47  ? 450 GLY C N   1 
ATOM   1576 C CA  . GLY A 1 193 ? 230.114 265.221 270.749 1.00 59.61  ? 450 GLY C CA  1 
ATOM   1577 C C   . GLY A 1 193 ? 228.618 265.246 270.974 1.00 62.56  ? 450 GLY C C   1 
ATOM   1578 O O   . GLY A 1 193 ? 227.912 264.426 270.377 1.00 63.96  ? 450 GLY C O   1 
ATOM   1579 N N   . SER A 1 194 ? 228.111 266.153 271.802 1.00 61.29  ? 451 SER C N   1 
ATOM   1580 C CA  . SER A 1 194 ? 226.680 266.227 272.048 1.00 59.05  ? 451 SER C CA  1 
ATOM   1581 C C   . SER A 1 194 ? 225.972 266.882 270.862 1.00 59.07  ? 451 SER C C   1 
ATOM   1582 O O   . SER A 1 194 ? 226.561 267.146 269.811 1.00 62.09  ? 451 SER C O   1 
ATOM   1583 C CB  . SER A 1 194 ? 226.399 266.985 273.342 1.00 62.47  ? 451 SER C CB  1 
ATOM   1584 O OG  . SER A 1 194 ? 227.261 268.099 273.479 1.00 71.57  ? 451 SER C OG  1 
ATOM   1585 N N   . HIS A 1 195 ? 224.681 267.142 271.039 1.00 47.94  ? 452 HIS C N   1 
ATOM   1586 C CA  . HIS A 1 195 ? 223.832 267.684 269.989 1.00 42.64  ? 452 HIS C CA  1 
ATOM   1587 C C   . HIS A 1 195 ? 223.114 268.920 270.509 1.00 44.54  ? 452 HIS C C   1 
ATOM   1588 O O   . HIS A 1 195 ? 222.659 268.946 271.655 1.00 46.39  ? 452 HIS C O   1 
ATOM   1589 C CB  . HIS A 1 195 ? 222.827 266.630 269.515 1.00 41.77  ? 452 HIS C CB  1 
ATOM   1590 C CG  . HIS A 1 195 ? 221.739 267.170 268.645 1.00 40.81  ? 452 HIS C CG  1 
ATOM   1591 N ND1 . HIS A 1 195 ? 220.471 267.432 269.117 1.00 40.07  ? 452 HIS C ND1 1 
ATOM   1592 C CD2 . HIS A 1 195 ? 221.722 267.483 267.328 1.00 38.66  ? 452 HIS C CD2 1 
ATOM   1593 C CE1 . HIS A 1 195 ? 219.722 267.891 268.131 1.00 43.21  ? 452 HIS C CE1 1 
ATOM   1594 N NE2 . HIS A 1 195 ? 220.458 267.932 267.035 1.00 41.15  ? 452 HIS C NE2 1 
ATOM   1595 N N   . ILE A 1 196 ? 223.022 269.948 269.666 1.00 52.54  ? 453 ILE C N   1 
ATOM   1596 C CA  . ILE A 1 196 ? 222.395 271.202 270.065 1.00 51.24  ? 453 ILE C CA  1 
ATOM   1597 C C   . ILE A 1 196 ? 221.125 271.434 269.255 1.00 51.84  ? 453 ILE C C   1 
ATOM   1598 O O   . ILE A 1 196 ? 220.027 271.498 269.818 1.00 49.93  ? 453 ILE C O   1 
ATOM   1599 C CB  . ILE A 1 196 ? 223.370 272.384 269.925 1.00 45.63  ? 453 ILE C CB  1 
ATOM   1600 C CG1 . ILE A 1 196 ? 224.788 271.948 270.292 1.00 45.16  ? 453 ILE C CG1 1 
ATOM   1601 C CG2 . ILE A 1 196 ? 222.931 273.538 270.804 1.00 51.06  ? 453 ILE C CG2 1 
ATOM   1602 C CD1 . ILE A 1 196 ? 225.767 273.090 270.403 1.00 46.05  ? 453 ILE C CD1 1 
ATOM   1603 N N   . HIS A 1 197 ? 221.254 271.555 267.936 1.00 47.42  ? 454 HIS C N   1 
ATOM   1604 C CA  . HIS A 1 197 ? 220.067 271.714 267.108 1.00 44.64  ? 454 HIS C CA  1 
ATOM   1605 C C   . HIS A 1 197 ? 220.367 271.315 265.671 1.00 53.26  ? 454 HIS C C   1 
ATOM   1606 O O   . HIS A 1 197 ? 221.489 271.479 265.177 1.00 56.02  ? 454 HIS C O   1 
ATOM   1607 C CB  . HIS A 1 197 ? 219.527 273.146 267.149 1.00 43.25  ? 454 HIS C CB  1 
ATOM   1608 C CG  . HIS A 1 197 ? 218.052 273.242 266.906 1.00 51.51  ? 454 HIS C CG  1 
ATOM   1609 N ND1 . HIS A 1 197 ? 217.501 274.129 266.007 1.00 53.72  ? 454 HIS C ND1 1 
ATOM   1610 C CD2 . HIS A 1 197 ? 217.014 272.560 267.445 1.00 54.18  ? 454 HIS C CD2 1 
ATOM   1611 C CE1 . HIS A 1 197 ? 216.187 273.991 266.004 1.00 47.76  ? 454 HIS C CE1 1 
ATOM   1612 N NE2 . HIS A 1 197 ? 215.866 273.045 266.867 1.00 47.62  ? 454 HIS C NE2 1 
ATOM   1613 N N   . THR A 1 198 ? 219.331 270.802 265.011 1.00 54.91  ? 455 THR C N   1 
ATOM   1614 C CA  . THR A 1 198 ? 219.382 270.392 263.617 1.00 52.45  ? 455 THR C CA  1 
ATOM   1615 C C   . THR A 1 198 ? 218.149 270.928 262.907 1.00 56.11  ? 455 THR C C   1 
ATOM   1616 O O   . THR A 1 198 ? 217.026 270.736 263.381 1.00 59.01  ? 455 THR C O   1 
ATOM   1617 C CB  . THR A 1 198 ? 219.439 268.867 263.489 1.00 46.38  ? 455 THR C CB  1 
ATOM   1618 O OG1 . THR A 1 198 ? 220.412 268.345 264.401 1.00 50.70  ? 455 THR C OG1 1 
ATOM   1619 C CG2 . THR A 1 198 ? 219.812 268.467 262.075 1.00 52.10  ? 455 THR C CG2 1 
ATOM   1620 N N   . PHE A 1 199 ? 218.361 271.595 261.779 1.00 53.42  ? 456 PHE C N   1 
ATOM   1621 C CA  . PHE A 1 199 ? 217.268 272.137 260.978 1.00 44.29  ? 456 PHE C CA  1 
ATOM   1622 C C   . PHE A 1 199 ? 216.846 271.078 259.966 1.00 56.02  ? 456 PHE C C   1 
ATOM   1623 O O   . PHE A 1 199 ? 217.634 270.689 259.098 1.00 53.12  ? 456 PHE C O   1 
ATOM   1624 C CB  . PHE A 1 199 ? 217.690 273.431 260.289 1.00 46.15  ? 456 PHE C CB  1 
ATOM   1625 C CG  . PHE A 1 199 ? 217.694 274.631 261.195 1.00 53.39  ? 456 PHE C CG  1 
ATOM   1626 C CD1 . PHE A 1 199 ? 216.535 275.356 261.414 1.00 53.12  ? 456 PHE C CD1 1 
ATOM   1627 C CD2 . PHE A 1 199 ? 218.859 275.039 261.820 1.00 56.54  ? 456 PHE C CD2 1 
ATOM   1628 C CE1 . PHE A 1 199 ? 216.537 276.462 262.241 1.00 50.75  ? 456 PHE C CE1 1 
ATOM   1629 C CE2 . PHE A 1 199 ? 218.868 276.142 262.650 1.00 50.37  ? 456 PHE C CE2 1 
ATOM   1630 C CZ  . PHE A 1 199 ? 217.705 276.854 262.860 1.00 52.09  ? 456 PHE C CZ  1 
ATOM   1631 N N   . LEU A 1 200 ? 215.605 270.615 260.074 1.00 60.22  ? 457 LEU C N   1 
ATOM   1632 C CA  . LEU A 1 200 ? 215.118 269.479 259.305 1.00 51.30  ? 457 LEU C CA  1 
ATOM   1633 C C   . LEU A 1 200 ? 214.276 269.955 258.129 1.00 51.57  ? 457 LEU C C   1 
ATOM   1634 O O   . LEU A 1 200 ? 213.421 270.833 258.286 1.00 58.17  ? 457 LEU C O   1 
ATOM   1635 C CB  . LEU A 1 200 ? 214.294 268.543 260.189 1.00 52.01  ? 457 LEU C CB  1 
ATOM   1636 C CG  . LEU A 1 200 ? 214.979 268.032 261.456 1.00 55.38  ? 457 LEU C CG  1 
ATOM   1637 C CD1 . LEU A 1 200 ? 213.949 267.521 262.445 1.00 55.00  ? 457 LEU C CD1 1 
ATOM   1638 C CD2 . LEU A 1 200 ? 215.984 266.948 261.119 1.00 57.84  ? 457 LEU C CD2 1 
ATOM   1639 N N   . ASP A 1 201 ? 214.521 269.367 256.958 1.00 56.51  ? 458 ASP C N   1 
ATOM   1640 C CA  . ASP A 1 201 ? 213.738 269.619 255.749 1.00 64.12  ? 458 ASP C CA  1 
ATOM   1641 C C   . ASP A 1 201 ? 213.759 271.101 255.371 1.00 63.74  ? 458 ASP C C   1 
ATOM   1642 O O   . ASP A 1 201 ? 212.736 271.787 255.358 1.00 63.30  ? 458 ASP C O   1 
ATOM   1643 C CB  . ASP A 1 201 ? 212.303 269.110 255.912 1.00 63.98  ? 458 ASP C CB  1 
ATOM   1644 C CG  . ASP A 1 201 ? 211.630 268.833 254.584 1.00 70.15  ? 458 ASP C CG  1 
ATOM   1645 O OD1 . ASP A 1 201 ? 212.180 269.241 253.541 1.00 72.38  ? 458 ASP C OD1 1 
ATOM   1646 O OD2 . ASP A 1 201 ? 210.552 268.203 254.583 1.00 71.13  ? 458 ASP C OD2 1 
ATOM   1647 N N   . VAL A 1 202 ? 214.955 271.585 255.058 1.00 60.78  ? 459 VAL C N   1 
ATOM   1648 C CA  . VAL A 1 202 ? 215.156 272.954 254.601 1.00 58.24  ? 459 VAL C CA  1 
ATOM   1649 C C   . VAL A 1 202 ? 215.171 272.945 253.080 1.00 58.52  ? 459 VAL C C   1 
ATOM   1650 O O   . VAL A 1 202 ? 215.993 272.258 252.463 1.00 60.64  ? 459 VAL C O   1 
ATOM   1651 C CB  . VAL A 1 202 ? 216.455 273.550 255.163 1.00 60.34  ? 459 VAL C CB  1 
ATOM   1652 C CG1 . VAL A 1 202 ? 216.702 274.918 254.566 1.00 61.93  ? 459 VAL C CG1 1 
ATOM   1653 C CG2 . VAL A 1 202 ? 216.387 273.634 256.675 1.00 59.69  ? 459 VAL C CG2 1 
ATOM   1654 N N   . SER A 1 203 ? 214.263 273.704 252.473 1.00 58.44  ? 460 SER C N   1 
ATOM   1655 C CA  . SER A 1 203 ? 214.175 273.792 251.018 1.00 55.77  ? 460 SER C CA  1 
ATOM   1656 C C   . SER A 1 203 ? 215.331 274.647 250.521 1.00 54.33  ? 460 SER C C   1 
ATOM   1657 O O   . SER A 1 203 ? 215.323 275.871 250.666 1.00 59.18  ? 460 SER C O   1 
ATOM   1658 C CB  . SER A 1 203 ? 212.832 274.372 250.594 1.00 61.51  ? 460 SER C CB  1 
ATOM   1659 O OG  . SER A 1 203 ? 211.761 273.623 251.137 1.00 64.77  ? 460 SER C OG  1 
ATOM   1660 N N   . PHE A 1 204 ? 216.332 274.002 249.934 1.00 54.73  ? 461 PHE C N   1 
ATOM   1661 C CA  . PHE A 1 204 ? 217.516 274.691 249.447 1.00 62.55  ? 461 PHE C CA  1 
ATOM   1662 C C   . PHE A 1 204 ? 217.387 274.957 247.953 1.00 65.81  ? 461 PHE C C   1 
ATOM   1663 O O   . PHE A 1 204 ? 217.030 274.059 247.185 1.00 66.81  ? 461 PHE C O   1 
ATOM   1664 C CB  . PHE A 1 204 ? 218.769 273.865 249.724 1.00 59.46  ? 461 PHE C CB  1 
ATOM   1665 C CG  . PHE A 1 204 ? 219.244 273.936 251.144 1.00 59.16  ? 461 PHE C CG  1 
ATOM   1666 C CD1 . PHE A 1 204 ? 219.897 275.059 251.612 1.00 60.13  ? 461 PHE C CD1 1 
ATOM   1667 C CD2 . PHE A 1 204 ? 219.053 272.873 252.006 1.00 63.85  ? 461 PHE C CD2 1 
ATOM   1668 C CE1 . PHE A 1 204 ? 220.342 275.124 252.915 1.00 62.76  ? 461 PHE C CE1 1 
ATOM   1669 C CE2 . PHE A 1 204 ? 219.497 272.935 253.310 1.00 56.47  ? 461 PHE C CE2 1 
ATOM   1670 C CZ  . PHE A 1 204 ? 220.142 274.061 253.764 1.00 57.47  ? 461 PHE C CZ  1 
ATOM   1671 N N   . SER A 1 205 ? 217.677 276.192 247.547 1.00 66.21  ? 462 SER C N   1 
ATOM   1672 C CA  . SER A 1 205 ? 217.606 276.562 246.140 1.00 61.46  ? 462 SER C CA  1 
ATOM   1673 C C   . SER A 1 205 ? 218.898 277.218 245.674 1.00 64.34  ? 462 SER C C   1 
ATOM   1674 O O   . SER A 1 205 ? 219.327 277.014 244.534 1.00 71.52  ? 462 SER C O   1 
ATOM   1675 C CB  . SER A 1 205 ? 216.422 277.497 245.895 1.00 64.07  ? 462 SER C CB  1 
ATOM   1676 O OG  . SER A 1 205 ? 216.540 278.676 246.672 1.00 68.58  ? 462 SER C OG  1 
ATOM   1677 N N   . GLU A 1 206 ? 219.526 278.004 246.542 1.00 60.76  ? 463 GLU C N   1 
ATOM   1678 C CA  . GLU A 1 206 ? 220.709 278.765 246.182 1.00 60.23  ? 463 GLU C CA  1 
ATOM   1679 C C   . GLU A 1 206 ? 221.932 278.221 246.914 1.00 67.49  ? 463 GLU C C   1 
ATOM   1680 O O   . GLU A 1 206 ? 221.858 277.235 247.651 1.00 72.05  ? 463 GLU C O   1 
ATOM   1681 C CB  . GLU A 1 206 ? 220.483 280.249 246.482 1.00 63.13  ? 463 GLU C CB  1 
ATOM   1682 C CG  . GLU A 1 206 ? 219.455 280.977 245.601 1.00 69.17  ? 463 GLU C CG  1 
ATOM   1683 C CD  . GLU A 1 206 ? 219.696 280.890 244.091 1.00 75.39  ? 463 GLU C CD  1 
ATOM   1684 O OE1 . GLU A 1 206 ? 218.993 281.614 243.356 1.00 76.90  ? 463 GLU C OE1 1 
ATOM   1685 O OE2 . GLU A 1 206 ? 220.589 280.152 243.624 1.00 76.29  ? 463 GLU C OE2 1 
ATOM   1686 N N   . ALA A 1 207 ? 223.075 278.870 246.711 1.00 60.41  ? 464 ALA C N   1 
ATOM   1687 C CA  . ALA A 1 207 ? 224.303 278.482 247.382 1.00 55.43  ? 464 ALA C CA  1 
ATOM   1688 C C   . ALA A 1 207 ? 224.265 278.909 248.845 1.00 56.78  ? 464 ALA C C   1 
ATOM   1689 O O   . ALA A 1 207 ? 223.453 279.742 249.258 1.00 64.56  ? 464 ALA C O   1 
ATOM   1690 C CB  . ALA A 1 207 ? 225.515 279.090 246.679 1.00 52.52  ? 464 ALA C CB  1 
ATOM   1691 N N   . LEU A 1 208 ? 225.156 278.324 249.640 1.00 52.30  ? 465 LEU C N   1 
ATOM   1692 C CA  . LEU A 1 208 ? 225.182 278.556 251.076 1.00 60.05  ? 465 LEU C CA  1 
ATOM   1693 C C   . LEU A 1 208 ? 226.544 279.085 251.501 1.00 67.64  ? 465 LEU C C   1 
ATOM   1694 O O   . LEU A 1 208 ? 227.582 278.616 251.028 1.00 70.21  ? 465 LEU C O   1 
ATOM   1695 C CB  . LEU A 1 208 ? 224.857 277.283 251.864 1.00 55.52  ? 465 LEU C CB  1 
ATOM   1696 C CG  . LEU A 1 208 ? 223.398 276.818 251.868 1.00 59.16  ? 465 LEU C CG  1 
ATOM   1697 C CD1 . LEU A 1 208 ? 222.470 277.930 252.336 1.00 60.26  ? 465 LEU C CD1 1 
ATOM   1698 C CD2 . LEU A 1 208 ? 222.960 276.268 250.528 1.00 60.07  ? 465 LEU C CD2 1 
ATOM   1699 N N   . TYR A 1 209 ? 226.525 280.059 252.406 1.00 60.75  ? 466 TYR C N   1 
ATOM   1700 C CA  . TYR A 1 209 ? 227.701 280.735 252.918 1.00 48.69  ? 466 TYR C CA  1 
ATOM   1701 C C   . TYR A 1 209 ? 227.773 280.550 254.427 1.00 43.17  ? 466 TYR C C   1 
ATOM   1702 O O   . TYR A 1 209 ? 226.737 280.523 255.096 1.00 43.40  ? 466 TYR C O   1 
ATOM   1703 C CB  . TYR A 1 209 ? 227.648 282.237 252.604 1.00 50.36  ? 466 TYR C CB  1 
ATOM   1704 C CG  . TYR A 1 209 ? 228.261 282.654 251.290 1.00 48.70  ? 466 TYR C CG  1 
ATOM   1705 C CD1 . TYR A 1 209 ? 229.594 282.401 251.009 1.00 50.63  ? 466 TYR C CD1 1 
ATOM   1706 C CD2 . TYR A 1 209 ? 227.508 283.330 250.341 1.00 43.41  ? 466 TYR C CD2 1 
ATOM   1707 C CE1 . TYR A 1 209 ? 230.156 282.793 249.812 1.00 54.62  ? 466 TYR C CE1 1 
ATOM   1708 C CE2 . TYR A 1 209 ? 228.061 283.726 249.144 1.00 42.82  ? 466 TYR C CE2 1 
ATOM   1709 C CZ  . TYR A 1 209 ? 229.384 283.456 248.884 1.00 46.57  ? 466 TYR C CZ  1 
ATOM   1710 O OH  . TYR A 1 209 ? 229.936 283.850 247.689 1.00 44.77  ? 466 TYR C OH  1 
ATOM   1711 N N   . PRO A 1 210 ? 228.966 280.402 254.992 1.00 48.32  ? 467 PRO C N   1 
ATOM   1712 C CA  . PRO A 1 210 ? 229.102 280.553 256.444 1.00 53.82  ? 467 PRO C CA  1 
ATOM   1713 C C   . PRO A 1 210 ? 228.856 282.000 256.840 1.00 54.97  ? 467 PRO C C   1 
ATOM   1714 O O   . PRO A 1 210 ? 229.190 282.924 256.098 1.00 54.83  ? 467 PRO C O   1 
ATOM   1715 C CB  . PRO A 1 210 ? 230.550 280.130 256.716 1.00 55.03  ? 467 PRO C CB  1 
ATOM   1716 C CG  . PRO A 1 210 ? 230.973 279.371 255.498 1.00 49.42  ? 467 PRO C CG  1 
ATOM   1717 C CD  . PRO A 1 210 ? 230.221 279.972 254.359 1.00 52.84  ? 467 PRO C CD  1 
ATOM   1718 N N   . VAL A 1 211 ? 228.259 282.199 258.013 1.00 48.14  ? 468 VAL C N   1 
ATOM   1719 C CA  . VAL A 1 211 ? 228.005 283.537 258.531 1.00 38.67  ? 468 VAL C CA  1 
ATOM   1720 C C   . VAL A 1 211 ? 228.377 283.575 260.006 1.00 45.45  ? 468 VAL C C   1 
ATOM   1721 O O   . VAL A 1 211 ? 228.009 282.679 260.775 1.00 55.40  ? 468 VAL C O   1 
ATOM   1722 C CB  . VAL A 1 211 ? 226.537 283.975 258.315 1.00 39.13  ? 468 VAL C CB  1 
ATOM   1723 C CG1 . VAL A 1 211 ? 225.570 282.943 258.853 1.00 55.48  ? 468 VAL C CG1 1 
ATOM   1724 C CG2 . VAL A 1 211 ? 226.282 285.323 258.962 1.00 43.09  ? 468 VAL C CG2 1 
ATOM   1725 N N   . PHE A 1 212 ? 229.125 284.609 260.394 1.00 40.44  ? 469 PHE C N   1 
ATOM   1726 C CA  . PHE A 1 212 ? 229.520 284.809 261.783 1.00 42.03  ? 469 PHE C CA  1 
ATOM   1727 C C   . PHE A 1 212 ? 229.278 286.263 262.150 1.00 37.88  ? 469 PHE C C   1 
ATOM   1728 O O   . PHE A 1 212 ? 229.719 287.162 261.428 1.00 50.02  ? 469 PHE C O   1 
ATOM   1729 C CB  . PHE A 1 212 ? 230.992 284.441 262.000 1.00 45.45  ? 469 PHE C CB  1 
ATOM   1730 C CG  . PHE A 1 212 ? 231.430 283.219 261.248 1.00 42.04  ? 469 PHE C CG  1 
ATOM   1731 C CD1 . PHE A 1 212 ? 231.920 283.321 259.961 1.00 35.50  ? 469 PHE C CD1 1 
ATOM   1732 C CD2 . PHE A 1 212 ? 231.350 281.968 261.831 1.00 48.76  ? 469 PHE C CD2 1 
ATOM   1733 C CE1 . PHE A 1 212 ? 232.321 282.199 259.269 1.00 41.23  ? 469 PHE C CE1 1 
ATOM   1734 C CE2 . PHE A 1 212 ? 231.750 280.844 261.142 1.00 49.46  ? 469 PHE C CE2 1 
ATOM   1735 C CZ  . PHE A 1 212 ? 232.236 280.960 259.860 1.00 46.65  ? 469 PHE C CZ  1 
ATOM   1736 N N   . ARG A 1 213 ? 228.586 286.498 263.263 1.00 36.74  ? 470 ARG C N   1 
ATOM   1737 C CA  . ARG A 1 213 ? 228.317 287.850 263.733 1.00 39.30  ? 470 ARG C CA  1 
ATOM   1738 C C   . ARG A 1 213 ? 228.601 287.943 265.226 1.00 33.61  ? 470 ARG C C   1 
ATOM   1739 O O   . ARG A 1 213 ? 228.326 287.005 265.984 1.00 44.37  ? 470 ARG C O   1 
ATOM   1740 C CB  . ARG A 1 213 ? 226.877 288.280 263.416 1.00 42.55  ? 470 ARG C CB  1 
ATOM   1741 C CG  . ARG A 1 213 ? 225.830 287.898 264.438 1.00 37.41  ? 470 ARG C CG  1 
ATOM   1742 C CD  . ARG A 1 213 ? 224.563 288.716 264.259 1.00 35.58  ? 470 ARG C CD  1 
ATOM   1743 N NE  . ARG A 1 213 ? 223.540 288.368 265.237 1.00 39.36  ? 470 ARG C NE  1 
ATOM   1744 C CZ  . ARG A 1 213 ? 222.511 289.142 265.552 1.00 44.37  ? 470 ARG C CZ  1 
ATOM   1745 N NH1 . ARG A 1 213 ? 222.340 290.326 264.989 1.00 49.61  ? 470 ARG C NH1 1 
ATOM   1746 N NH2 . ARG A 1 213 ? 221.628 288.714 266.450 1.00 29.00  ? 470 ARG C NH2 1 
ATOM   1747 N N   . ILE A 1 214 ? 229.186 289.066 265.632 1.00 32.64  ? 471 ILE C N   1 
ATOM   1748 C CA  . ILE A 1 214 ? 229.546 289.330 267.018 1.00 42.38  ? 471 ILE C CA  1 
ATOM   1749 C C   . ILE A 1 214 ? 229.089 290.738 267.364 1.00 49.31  ? 471 ILE C C   1 
ATOM   1750 O O   . ILE A 1 214 ? 229.362 291.684 266.618 1.00 56.21  ? 471 ILE C O   1 
ATOM   1751 C CB  . ILE A 1 214 ? 231.060 289.177 267.252 1.00 41.62  ? 471 ILE C CB  1 
ATOM   1752 C CG1 . ILE A 1 214 ? 231.842 289.794 266.093 1.00 38.46  ? 471 ILE C CG1 1 
ATOM   1753 C CG2 . ILE A 1 214 ? 231.426 287.712 267.408 1.00 49.93  ? 471 ILE C CG2 1 
ATOM   1754 C CD1 . ILE A 1 214 ? 233.327 289.554 266.164 1.00 41.28  ? 471 ILE C CD1 1 
ATOM   1755 N N   . LEU A 1 215 ? 228.388 290.876 268.486 1.00 45.94  ? 472 LEU C N   1 
ATOM   1756 C CA  . LEU A 1 215 ? 227.876 292.177 268.900 1.00 43.51  ? 472 LEU C CA  1 
ATOM   1757 C C   . LEU A 1 215 ? 228.808 292.873 269.888 1.00 43.48  ? 472 LEU C C   1 
ATOM   1758 O O   . LEU A 1 215 ? 229.307 293.969 269.617 1.00 49.24  ? 472 LEU C O   1 
ATOM   1759 C CB  . LEU A 1 215 ? 226.480 292.019 269.513 1.00 41.23  ? 472 LEU C CB  1 
ATOM   1760 C CG  . LEU A 1 215 ? 225.290 292.088 268.561 1.00 45.56  ? 472 LEU C CG  1 
ATOM   1761 C CD1 . LEU A 1 215 ? 224.007 292.286 269.344 1.00 48.15  ? 472 LEU C CD1 1 
ATOM   1762 C CD2 . LEU A 1 215 ? 225.481 293.204 267.554 1.00 45.49  ? 472 LEU C CD2 1 
ATOM   1763 N N   . THR A 1 216 ? 229.057 292.243 271.030 1.00 49.27  ? 473 THR C N   1 
ATOM   1764 C CA  . THR A 1 216 ? 229.713 292.915 272.139 1.00 51.81  ? 473 THR C CA  1 
ATOM   1765 C C   . THR A 1 216 ? 231.214 293.041 271.912 1.00 57.05  ? 473 THR C C   1 
ATOM   1766 O O   . THR A 1 216 ? 231.837 292.220 271.235 1.00 57.90  ? 473 THR C O   1 
ATOM   1767 C CB  . THR A 1 216 ? 229.456 292.165 273.444 1.00 60.33  ? 473 THR C CB  1 
ATOM   1768 O OG1 . THR A 1 216 ? 230.078 290.876 273.386 1.00 71.13  ? 473 THR C OG1 1 
ATOM   1769 C CG2 . THR A 1 216 ? 227.964 291.992 273.670 1.00 62.67  ? 473 THR C CG2 1 
ATOM   1770 N N   . LEU A 1 217 ? 231.788 294.092 272.490 1.00 64.76  ? 474 LEU C N   1 
ATOM   1771 C CA  . LEU A 1 217 ? 233.235 294.231 272.523 1.00 62.44  ? 474 LEU C CA  1 
ATOM   1772 C C   . LEU A 1 217 ? 233.831 293.165 273.430 1.00 68.85  ? 474 LEU C C   1 
ATOM   1773 O O   . LEU A 1 217 ? 233.541 293.114 274.627 1.00 69.89  ? 474 LEU C O   1 
ATOM   1774 C CB  . LEU A 1 217 ? 233.630 295.618 273.030 1.00 61.92  ? 474 LEU C CB  1 
ATOM   1775 C CG  . LEU A 1 217 ? 233.956 296.717 272.018 1.00 61.20  ? 474 LEU C CG  1 
ATOM   1776 C CD1 . LEU A 1 217 ? 235.238 296.396 271.266 1.00 61.68  ? 474 LEU C CD1 1 
ATOM   1777 C CD2 . LEU A 1 217 ? 232.799 296.943 271.061 1.00 62.02  ? 474 LEU C CD2 1 
ATOM   1778 N N   . GLU A 1 218 ? 234.669 292.302 272.854 1.00 68.37  ? 475 GLU C N   1 
ATOM   1779 C CA  . GLU A 1 218 ? 235.263 291.245 273.656 1.00 66.51  ? 475 GLU C CA  1 
ATOM   1780 C C   . GLU A 1 218 ? 236.713 291.060 273.255 1.00 68.64  ? 475 GLU C C   1 
ATOM   1781 O O   . GLU A 1 218 ? 237.047 291.262 272.080 1.00 64.26  ? 475 GLU C O   1 
ATOM   1782 C CB  . GLU A 1 218 ? 234.496 289.931 273.488 1.00 60.79  ? 475 GLU C CB  1 
ATOM   1783 C CG  . GLU A 1 218 ? 233.255 289.830 274.350 1.00 58.71  ? 475 GLU C CG  1 
ATOM   1784 C CD  . GLU A 1 218 ? 233.100 288.465 274.979 1.00 73.38  ? 475 GLU C CD  1 
ATOM   1785 O OE1 . GLU A 1 218 ? 233.863 288.150 275.915 1.00 77.94  ? 475 GLU C OE1 1 
ATOM   1786 O OE2 . GLU A 1 218 ? 232.218 287.702 274.532 1.00 76.20  ? 475 GLU C OE2 1 
ATOM   1787 N N   . PRO A 1 219 ? 237.594 290.685 274.182 1.00 65.97  ? 476 PRO C N   1 
ATOM   1788 C CA  . PRO A 1 219 ? 238.990 290.409 273.830 1.00 63.61  ? 476 PRO C CA  1 
ATOM   1789 C C   . PRO A 1 219 ? 239.234 289.027 273.244 1.00 63.91  ? 476 PRO C C   1 
ATOM   1790 O O   . PRO A 1 219 ? 240.394 288.622 273.133 1.00 61.48  ? 476 PRO C O   1 
ATOM   1791 C CB  . PRO A 1 219 ? 239.708 290.558 275.179 1.00 65.41  ? 476 PRO C CB  1 
ATOM   1792 C CG  . PRO A 1 219 ? 238.683 290.155 276.181 1.00 60.92  ? 476 PRO C CG  1 
ATOM   1793 C CD  . PRO A 1 219 ? 237.359 290.612 275.635 1.00 59.38  ? 476 PRO C CD  1 
ATOM   1794 N N   . THR A 1 220 ? 238.186 288.297 272.873 1.00 64.37  ? 477 THR C N   1 
ATOM   1795 C CA  . THR A 1 220 ? 238.307 286.945 272.346 1.00 60.54  ? 477 THR C CA  1 
ATOM   1796 C C   . THR A 1 220 ? 237.854 286.922 270.893 1.00 59.48  ? 477 THR C C   1 
ATOM   1797 O O   . THR A 1 220 ? 236.777 287.430 270.565 1.00 52.53  ? 477 THR C O   1 
ATOM   1798 C CB  . THR A 1 220 ? 237.481 285.960 273.173 1.00 58.63  ? 477 THR C CB  1 
ATOM   1799 O OG1 . THR A 1 220 ? 237.638 286.258 274.566 1.00 58.86  ? 477 THR C OG1 1 
ATOM   1800 C CG2 . THR A 1 220 ? 237.941 284.536 272.912 1.00 60.68  ? 477 THR C CG2 1 
ATOM   1801 N N   . ALA A 1 221 ? 238.673 286.327 270.033 1.00 62.11  ? 478 ALA C N   1 
ATOM   1802 C CA  . ALA A 1 221 ? 238.418 286.282 268.602 1.00 53.31  ? 478 ALA C CA  1 
ATOM   1803 C C   . ALA A 1 221 ? 237.771 284.958 268.219 1.00 58.04  ? 478 ALA C C   1 
ATOM   1804 O O   . ALA A 1 221 ? 238.127 283.903 268.749 1.00 63.48  ? 478 ALA C O   1 
ATOM   1805 C CB  . ALA A 1 221 ? 239.713 286.473 267.813 1.00 52.03  ? 478 ALA C CB  1 
ATOM   1806 N N   . LEU A 1 222 ? 236.822 285.024 267.291 1.00 60.27  ? 479 LEU C N   1 
ATOM   1807 C CA  . LEU A 1 222 ? 236.136 283.838 266.793 1.00 59.21  ? 479 LEU C CA  1 
ATOM   1808 C C   . LEU A 1 222 ? 237.027 283.163 265.757 1.00 61.49  ? 479 LEU C C   1 
ATOM   1809 O O   . LEU A 1 222 ? 237.237 283.700 264.666 1.00 68.13  ? 479 LEU C O   1 
ATOM   1810 C CB  . LEU A 1 222 ? 234.784 284.224 266.200 1.00 59.08  ? 479 LEU C CB  1 
ATOM   1811 C CG  . LEU A 1 222 ? 233.702 283.152 266.107 1.00 57.32  ? 479 LEU C CG  1 
ATOM   1812 C CD1 . LEU A 1 222 ? 233.480 282.511 267.462 1.00 62.56  ? 479 LEU C CD1 1 
ATOM   1813 C CD2 . LEU A 1 222 ? 232.413 283.753 265.582 1.00 48.47  ? 479 LEU C CD2 1 
ATOM   1814 N N   . THR A 1 223 ? 237.552 281.989 266.093 1.00 54.34  ? 480 THR C N   1 
ATOM   1815 C CA  . THR A 1 223 ? 238.519 281.296 265.252 1.00 55.73  ? 480 THR C CA  1 
ATOM   1816 C C   . THR A 1 223 ? 237.844 280.154 264.507 1.00 60.17  ? 480 THR C C   1 
ATOM   1817 O O   . THR A 1 223 ? 237.090 279.376 265.101 1.00 68.24  ? 480 THR C O   1 
ATOM   1818 C CB  . THR A 1 223 ? 239.682 280.754 266.083 1.00 58.82  ? 480 THR C CB  1 
ATOM   1819 O OG1 . THR A 1 223 ? 240.131 281.760 266.999 1.00 71.78  ? 480 THR C OG1 1 
ATOM   1820 C CG2 . THR A 1 223 ? 240.834 280.344 265.183 1.00 60.70  ? 480 THR C CG2 1 
ATOM   1821 N N   . ILE A 1 224 ? 238.110 280.063 263.209 1.00 62.09  ? 481 ILE C N   1 
ATOM   1822 C CA  . ILE A 1 224 ? 237.641 278.962 262.376 1.00 60.89  ? 481 ILE C CA  1 
ATOM   1823 C C   . ILE A 1 224 ? 238.846 278.061 262.139 1.00 59.78  ? 481 ILE C C   1 
ATOM   1824 O O   . ILE A 1 224 ? 239.815 278.461 261.486 1.00 65.09  ? 481 ILE C O   1 
ATOM   1825 C CB  . ILE A 1 224 ? 237.028 279.434 261.049 1.00 57.28  ? 481 ILE C CB  1 
ATOM   1826 C CG1 . ILE A 1 224 ? 235.649 280.101 261.211 1.00 56.97  ? 481 ILE C CG1 1 
ATOM   1827 C CG2 . ILE A 1 224 ? 236.916 278.270 260.079 1.00 55.35  ? 481 ILE C CG2 1 
ATOM   1828 C CD1 . ILE A 1 224 ? 235.509 281.188 262.257 1.00 58.57  ? 481 ILE C CD1 1 
ATOM   1829 N N   . CYS A 1 225 ? 238.800 276.849 262.673 1.00 70.70  ? 482 CYS C N   1 
ATOM   1830 C CA  . CYS A 1 225 ? 239.925 275.951 262.463 1.00 73.45  ? 482 CYS C CA  1 
ATOM   1831 C C   . CYS A 1 225 ? 239.627 275.004 261.302 1.00 78.78  ? 482 CYS C C   1 
ATOM   1832 O O   . CYS A 1 225 ? 238.528 274.451 261.219 1.00 83.51  ? 482 CYS C O   1 
ATOM   1833 C CB  . CYS A 1 225 ? 240.217 275.151 263.729 1.00 77.00  ? 482 CYS C CB  1 
ATOM   1834 S SG  . CYS A 1 225 ? 241.943 274.650 263.917 1.00 84.68  ? 482 CYS C SG  1 
ATOM   1835 N N   . PRO A 1 226 ? 240.580 274.801 260.396 1.00 83.13  ? 483 PRO C N   1 
ATOM   1836 C CA  . PRO A 1 226 ? 240.313 273.956 259.227 1.00 83.99  ? 483 PRO C CA  1 
ATOM   1837 C C   . PRO A 1 226 ? 240.428 272.476 259.543 1.00 86.68  ? 483 PRO C C   1 
ATOM   1838 O O   . PRO A 1 226 ? 240.600 272.091 260.704 1.00 87.26  ? 483 PRO C O   1 
ATOM   1839 C CB  . PRO A 1 226 ? 241.382 274.400 258.222 1.00 83.56  ? 483 PRO C CB  1 
ATOM   1840 C CG  . PRO A 1 226 ? 242.488 274.981 259.051 1.00 83.66  ? 483 PRO C CG  1 
ATOM   1841 C CD  . PRO A 1 226 ? 241.976 275.265 260.440 1.00 82.25  ? 483 PRO C CD  1 
ATOM   1842 N N   . ALA A 1 227 ? 240.320 271.641 258.515 1.00 105.07 ? 484 ALA C N   1 
ATOM   1843 C CA  . ALA A 1 227 ? 240.443 270.197 258.672 1.00 109.55 ? 484 ALA C CA  1 
ATOM   1844 C C   . ALA A 1 227 ? 241.805 269.813 259.242 1.00 107.22 ? 484 ALA C C   1 
ATOM   1845 O O   . ALA A 1 227 ? 241.914 269.411 260.400 1.00 105.63 ? 484 ALA C O   1 
ATOM   1846 C CB  . ALA A 1 227 ? 240.216 269.503 257.343 1.00 107.68 ? 484 ALA C CB  1 
ATOM   1847 N N   . TRP B 1 9   ? 229.358 243.996 231.722 1.00 233.64 ? 266 TRP D N   1 
ATOM   1848 C CA  . TRP B 1 9   ? 230.251 243.873 232.868 1.00 234.14 ? 266 TRP D CA  1 
ATOM   1849 C C   . TRP B 1 9   ? 229.841 244.823 233.988 1.00 234.51 ? 266 TRP D C   1 
ATOM   1850 O O   . TRP B 1 9   ? 230.079 244.550 235.165 1.00 234.74 ? 266 TRP D O   1 
ATOM   1851 C CB  . TRP B 1 9   ? 231.699 244.146 232.453 1.00 234.27 ? 266 TRP D CB  1 
ATOM   1852 C CG  . TRP B 1 9   ? 232.685 243.975 233.569 1.00 234.77 ? 266 TRP D CG  1 
ATOM   1853 C CD1 . TRP B 1 9   ? 233.032 242.807 234.184 1.00 234.20 ? 266 TRP D CD1 1 
ATOM   1854 C CD2 . TRP B 1 9   ? 233.449 245.006 234.206 1.00 235.14 ? 266 TRP D CD2 1 
ATOM   1855 N NE1 . TRP B 1 9   ? 233.967 243.047 235.163 1.00 234.58 ? 266 TRP D NE1 1 
ATOM   1856 C CE2 . TRP B 1 9   ? 234.240 244.389 235.196 1.00 235.23 ? 266 TRP D CE2 1 
ATOM   1857 C CE3 . TRP B 1 9   ? 233.543 246.391 234.034 1.00 234.37 ? 266 TRP D CE3 1 
ATOM   1858 C CZ2 . TRP B 1 9   ? 235.111 245.109 236.011 1.00 234.80 ? 266 TRP D CZ2 1 
ATOM   1859 C CZ3 . TRP B 1 9   ? 234.409 247.103 234.845 1.00 233.90 ? 266 TRP D CZ3 1 
ATOM   1860 C CH2 . TRP B 1 9   ? 235.181 246.461 235.820 1.00 234.03 ? 266 TRP D CH2 1 
ATOM   1861 N N   . SER B 1 10  ? 229.229 245.944 233.615 1.00 213.10 ? 267 SER D N   1 
ATOM   1862 C CA  . SER B 1 10  ? 228.804 246.953 234.575 1.00 211.71 ? 267 SER D CA  1 
ATOM   1863 C C   . SER B 1 10  ? 227.463 246.636 235.223 1.00 210.85 ? 267 SER D C   1 
ATOM   1864 O O   . SER B 1 10  ? 227.127 247.250 236.240 1.00 210.13 ? 267 SER D O   1 
ATOM   1865 C CB  . SER B 1 10  ? 228.735 248.326 233.899 1.00 211.07 ? 267 SER D CB  1 
ATOM   1866 O OG  . SER B 1 10  ? 227.551 248.456 233.130 1.00 210.92 ? 267 SER D OG  1 
ATOM   1867 N N   . THR B 1 11  ? 226.699 245.689 234.673 1.00 199.40 ? 268 THR D N   1 
ATOM   1868 C CA  . THR B 1 11  ? 225.382 245.379 235.223 1.00 198.28 ? 268 THR D CA  1 
ATOM   1869 C C   . THR B 1 11  ? 225.491 244.845 236.647 1.00 197.02 ? 268 THR D C   1 
ATOM   1870 O O   . THR B 1 11  ? 224.967 245.447 237.591 1.00 195.84 ? 268 THR D O   1 
ATOM   1871 C CB  . THR B 1 11  ? 224.659 244.375 234.322 1.00 198.33 ? 268 THR D CB  1 
ATOM   1872 O OG1 . THR B 1 11  ? 224.414 244.969 233.041 1.00 198.49 ? 268 THR D OG1 1 
ATOM   1873 C CG2 . THR B 1 11  ? 223.334 243.962 234.945 1.00 197.61 ? 268 THR D CG2 1 
ATOM   1874 N N   . MET B 1 12  ? 226.173 243.711 236.824 1.00 188.81 ? 269 MET D N   1 
ATOM   1875 C CA  . MET B 1 12  ? 226.359 243.179 238.168 1.00 187.37 ? 269 MET D CA  1 
ATOM   1876 C C   . MET B 1 12  ? 227.338 244.025 238.970 1.00 186.81 ? 269 MET D C   1 
ATOM   1877 O O   . MET B 1 12  ? 227.267 244.052 240.204 1.00 185.34 ? 269 MET D O   1 
ATOM   1878 C CB  . MET B 1 12  ? 226.836 241.723 238.126 1.00 187.30 ? 269 MET D CB  1 
ATOM   1879 C CG  . MET B 1 12  ? 228.053 241.439 237.243 1.00 188.43 ? 269 MET D CG  1 
ATOM   1880 S SD  . MET B 1 12  ? 228.044 242.149 235.584 1.00 192.71 ? 269 MET D SD  1 
ATOM   1881 C CE  . MET B 1 12  ? 226.608 241.343 234.868 1.00 189.17 ? 269 MET D CE  1 
ATOM   1882 N N   . LYS B 1 13  ? 228.250 244.726 238.292 1.00 177.69 ? 270 LYS D N   1 
ATOM   1883 C CA  . LYS B 1 13  ? 229.187 245.591 238.999 1.00 176.97 ? 270 LYS D CA  1 
ATOM   1884 C C   . LYS B 1 13  ? 228.464 246.707 239.739 1.00 175.31 ? 270 LYS D C   1 
ATOM   1885 O O   . LYS B 1 13  ? 228.833 247.039 240.871 1.00 174.25 ? 270 LYS D O   1 
ATOM   1886 C CB  . LYS B 1 13  ? 230.207 246.176 238.022 1.00 176.91 ? 270 LYS D CB  1 
ATOM   1887 C CG  . LYS B 1 13  ? 231.500 246.631 238.679 1.00 176.01 ? 270 LYS D CG  1 
ATOM   1888 C CD  . LYS B 1 13  ? 231.520 248.137 238.878 1.00 175.44 ? 270 LYS D CD  1 
ATOM   1889 C CE  . LYS B 1 13  ? 232.863 248.604 239.416 1.00 175.88 ? 270 LYS D CE  1 
ATOM   1890 N NZ  . LYS B 1 13  ? 232.867 250.063 239.712 1.00 175.73 ? 270 LYS D NZ  1 
ATOM   1891 N N   . GLN B 1 14  ? 227.445 247.305 239.116 1.00 158.94 ? 271 GLN D N   1 
ATOM   1892 C CA  . GLN B 1 14  ? 226.649 248.310 239.810 1.00 157.41 ? 271 GLN D CA  1 
ATOM   1893 C C   . GLN B 1 14  ? 225.919 247.702 241.000 1.00 156.41 ? 271 GLN D C   1 
ATOM   1894 O O   . GLN B 1 14  ? 226.047 248.188 242.130 1.00 154.31 ? 271 GLN D O   1 
ATOM   1895 C CB  . GLN B 1 14  ? 225.660 248.955 238.838 1.00 158.83 ? 271 GLN D CB  1 
ATOM   1896 C CG  . GLN B 1 14  ? 224.402 249.506 239.491 1.00 158.54 ? 271 GLN D CG  1 
ATOM   1897 C CD  . GLN B 1 14  ? 223.189 248.630 239.246 1.00 158.32 ? 271 GLN D CD  1 
ATOM   1898 O OE1 . GLN B 1 14  ? 222.914 248.232 238.114 1.00 158.88 ? 271 GLN D OE1 1 
ATOM   1899 N NE2 . GLN B 1 14  ? 222.455 248.325 240.310 1.00 157.01 ? 271 GLN D NE2 1 
ATOM   1900 N N   . GLU B 1 15  ? 225.185 246.609 240.776 1.00 150.05 ? 272 GLU D N   1 
ATOM   1901 C CA  . GLU B 1 15  ? 224.434 245.977 241.855 1.00 149.17 ? 272 GLU D CA  1 
ATOM   1902 C C   . GLU B 1 15  ? 225.336 245.524 242.994 1.00 148.74 ? 272 GLU D C   1 
ATOM   1903 O O   . GLU B 1 15  ? 224.855 245.332 244.114 1.00 148.67 ? 272 GLU D O   1 
ATOM   1904 C CB  . GLU B 1 15  ? 223.636 244.790 241.315 1.00 150.07 ? 272 GLU D CB  1 
ATOM   1905 C CG  . GLU B 1 15  ? 222.376 244.475 242.107 1.00 150.53 ? 272 GLU D CG  1 
ATOM   1906 C CD  . GLU B 1 15  ? 222.631 243.522 243.257 1.00 150.79 ? 272 GLU D CD  1 
ATOM   1907 O OE1 . GLU B 1 15  ? 223.671 242.832 243.240 1.00 151.05 ? 272 GLU D OE1 1 
ATOM   1908 O OE2 . GLU B 1 15  ? 221.791 243.464 244.180 1.00 149.96 ? 272 GLU D OE2 1 
ATOM   1909 N N   . GLN B 1 16  ? 226.627 245.335 242.734 1.00 136.53 ? 273 GLN D N   1 
ATOM   1910 C CA  . GLN B 1 16  ? 227.557 245.062 243.822 1.00 136.09 ? 273 GLN D CA  1 
ATOM   1911 C C   . GLN B 1 16  ? 227.995 246.354 244.505 1.00 136.46 ? 273 GLN D C   1 
ATOM   1912 O O   . GLN B 1 16  ? 227.712 246.574 245.690 1.00 138.40 ? 273 GLN D O   1 
ATOM   1913 C CB  . GLN B 1 16  ? 228.766 244.290 243.288 1.00 136.03 ? 273 GLN D CB  1 
ATOM   1914 C CG  . GLN B 1 16  ? 229.976 244.283 244.209 1.00 137.45 ? 273 GLN D CG  1 
ATOM   1915 C CD  . GLN B 1 16  ? 229.713 243.573 245.521 1.00 139.68 ? 273 GLN D CD  1 
ATOM   1916 O OE1 . GLN B 1 16  ? 228.862 242.687 245.603 1.00 141.16 ? 273 GLN D OE1 1 
ATOM   1917 N NE2 . GLN B 1 16  ? 230.453 243.952 246.556 1.00 139.46 ? 273 GLN D NE2 1 
ATOM   1918 N N   . SER B 1 17  ? 228.657 247.237 243.752 1.00 119.83 ? 274 SER D N   1 
ATOM   1919 C CA  . SER B 1 17  ? 229.352 248.368 244.357 1.00 118.25 ? 274 SER D CA  1 
ATOM   1920 C C   . SER B 1 17  ? 228.380 249.383 244.943 1.00 116.33 ? 274 SER D C   1 
ATOM   1921 O O   . SER B 1 17  ? 228.560 249.834 246.079 1.00 116.27 ? 274 SER D O   1 
ATOM   1922 C CB  . SER B 1 17  ? 230.260 249.037 243.326 1.00 120.22 ? 274 SER D CB  1 
ATOM   1923 O OG  . SER B 1 17  ? 230.663 250.321 243.770 1.00 116.47 ? 274 SER D OG  1 
ATOM   1924 N N   . THR B 1 18  ? 227.361 249.780 244.177 1.00 116.39 ? 275 THR D N   1 
ATOM   1925 C CA  . THR B 1 18  ? 226.458 250.822 244.654 1.00 118.71 ? 275 THR D CA  1 
ATOM   1926 C C   . THR B 1 18  ? 225.673 250.361 245.875 1.00 116.32 ? 275 THR D C   1 
ATOM   1927 O O   . THR B 1 18  ? 225.496 251.122 246.832 1.00 116.91 ? 275 THR D O   1 
ATOM   1928 C CB  . THR B 1 18  ? 225.514 251.268 243.536 1.00 119.17 ? 275 THR D CB  1 
ATOM   1929 O OG1 . THR B 1 18  ? 224.363 250.415 243.502 1.00 116.80 ? 275 THR D OG1 1 
ATOM   1930 C CG2 . THR B 1 18  ? 226.223 251.257 242.187 1.00 120.05 ? 275 THR D CG2 1 
ATOM   1931 N N   . ARG B 1 19  ? 225.201 249.113 245.871 1.00 101.07 ? 276 ARG D N   1 
ATOM   1932 C CA  . ARG B 1 19  ? 224.461 248.622 247.029 1.00 100.13 ? 276 ARG D CA  1 
ATOM   1933 C C   . ARG B 1 19  ? 225.369 248.439 248.239 1.00 100.53 ? 276 ARG D C   1 
ATOM   1934 O O   . ARG B 1 19  ? 224.955 248.712 249.371 1.00 101.91 ? 276 ARG D O   1 
ATOM   1935 C CB  . ARG B 1 19  ? 223.723 247.325 246.691 1.00 103.27 ? 276 ARG D CB  1 
ATOM   1936 C CG  . ARG B 1 19  ? 222.938 247.320 245.370 1.00 107.99 ? 276 ARG D CG  1 
ATOM   1937 C CD  . ARG B 1 19  ? 222.195 248.625 245.044 1.00 104.48 ? 276 ARG D CD  1 
ATOM   1938 N NE  . ARG B 1 19  ? 221.564 249.253 246.200 1.00 104.20 ? 276 ARG D NE  1 
ATOM   1939 C CZ  . ARG B 1 19  ? 220.512 248.765 246.843 1.00 106.02 ? 276 ARG D CZ  1 
ATOM   1940 N NH1 . ARG B 1 19  ? 219.927 247.642 246.462 1.00 106.94 ? 276 ARG D NH1 1 
ATOM   1941 N NH2 . ARG B 1 19  ? 220.031 249.424 247.894 1.00 106.13 ? 276 ARG D NH2 1 
ATOM   1942 N N   . VAL B 1 20  ? 226.614 248.001 248.031 1.00 96.72  ? 277 VAL D N   1 
ATOM   1943 C CA  . VAL B 1 20  ? 227.545 247.896 249.154 1.00 97.88  ? 277 VAL D CA  1 
ATOM   1944 C C   . VAL B 1 20  ? 227.820 249.275 249.748 1.00 102.19 ? 277 VAL D C   1 
ATOM   1945 O O   . VAL B 1 20  ? 227.843 249.455 250.974 1.00 102.80 ? 277 VAL D O   1 
ATOM   1946 C CB  . VAL B 1 20  ? 228.842 247.197 248.711 1.00 97.95  ? 277 VAL D CB  1 
ATOM   1947 C CG1 . VAL B 1 20  ? 230.006 247.608 249.598 1.00 99.01  ? 277 VAL D CG1 1 
ATOM   1948 C CG2 . VAL B 1 20  ? 228.657 245.692 248.738 1.00 98.00  ? 277 VAL D CG2 1 
ATOM   1949 N N   . LYS B 1 21  ? 228.034 250.270 248.883 1.00 87.88  ? 278 LYS D N   1 
ATOM   1950 C CA  . LYS B 1 21  ? 228.291 251.625 249.358 1.00 77.88  ? 278 LYS D CA  1 
ATOM   1951 C C   . LYS B 1 21  ? 227.079 252.199 250.078 1.00 80.53  ? 278 LYS D C   1 
ATOM   1952 O O   . LYS B 1 21  ? 227.226 252.880 251.097 1.00 87.74  ? 278 LYS D O   1 
ATOM   1953 C CB  . LYS B 1 21  ? 228.702 252.524 248.191 1.00 81.25  ? 278 LYS D CB  1 
ATOM   1954 C CG  . LYS B 1 21  ? 230.143 252.360 247.647 1.00 87.67  ? 278 LYS D CG  1 
ATOM   1955 C CD  . LYS B 1 21  ? 231.244 251.872 248.618 1.00 85.00  ? 278 LYS D CD  1 
ATOM   1956 C CE  . LYS B 1 21  ? 231.317 252.625 249.952 1.00 82.37  ? 278 LYS D CE  1 
ATOM   1957 N NZ  . LYS B 1 21  ? 232.279 251.991 250.893 1.00 84.32  ? 278 LYS D NZ  1 
ATOM   1958 N N   . LEU B 1 22  ? 225.875 251.937 249.565 1.00 66.81  ? 279 LEU D N   1 
ATOM   1959 C CA  . LEU B 1 22  ? 224.667 252.374 250.254 1.00 67.20  ? 279 LEU D CA  1 
ATOM   1960 C C   . LEU B 1 22  ? 224.528 251.706 251.615 1.00 68.33  ? 279 LEU D C   1 
ATOM   1961 O O   . LEU B 1 22  ? 224.126 252.355 252.587 1.00 72.00  ? 279 LEU D O   1 
ATOM   1962 C CB  . LEU B 1 22  ? 223.440 252.088 249.390 1.00 64.26  ? 279 LEU D CB  1 
ATOM   1963 C CG  . LEU B 1 22  ? 222.114 252.703 249.839 1.00 65.94  ? 279 LEU D CG  1 
ATOM   1964 C CD1 . LEU B 1 22  ? 222.315 254.124 250.330 1.00 74.22  ? 279 LEU D CD1 1 
ATOM   1965 C CD2 . LEU B 1 22  ? 221.104 252.668 248.707 1.00 66.52  ? 279 LEU D CD2 1 
ATOM   1966 N N   . LEU B 1 23  ? 224.858 250.416 251.705 1.00 70.87  ? 280 LEU D N   1 
ATOM   1967 C CA  . LEU B 1 23  ? 224.782 249.717 252.983 1.00 69.96  ? 280 LEU D CA  1 
ATOM   1968 C C   . LEU B 1 23  ? 225.753 250.321 253.989 1.00 71.53  ? 280 LEU D C   1 
ATOM   1969 O O   . LEU B 1 23  ? 225.393 250.555 255.150 1.00 75.64  ? 280 LEU D O   1 
ATOM   1970 C CB  . LEU B 1 23  ? 225.048 248.222 252.767 1.00 72.32  ? 280 LEU D CB  1 
ATOM   1971 C CG  . LEU B 1 23  ? 225.156 247.170 253.882 1.00 75.54  ? 280 LEU D CG  1 
ATOM   1972 C CD1 . LEU B 1 23  ? 225.156 245.794 253.245 1.00 74.21  ? 280 LEU D CD1 1 
ATOM   1973 C CD2 . LEU B 1 23  ? 226.400 247.308 254.751 1.00 72.95  ? 280 LEU D CD2 1 
ATOM   1974 N N   . GLU B 1 24  ? 226.990 250.586 253.565 1.00 62.49  ? 281 GLU D N   1 
ATOM   1975 C CA  . GLU B 1 24  ? 227.945 251.182 254.492 1.00 64.14  ? 281 GLU D CA  1 
ATOM   1976 C C   . GLU B 1 24  ? 227.571 252.612 254.857 1.00 68.10  ? 281 GLU D C   1 
ATOM   1977 O O   . GLU B 1 24  ? 227.784 253.026 256.004 1.00 69.32  ? 281 GLU D O   1 
ATOM   1978 C CB  . GLU B 1 24  ? 229.359 251.144 253.917 1.00 64.29  ? 281 GLU D CB  1 
ATOM   1979 C CG  . GLU B 1 24  ? 230.430 251.011 254.989 1.00 64.49  ? 281 GLU D CG  1 
ATOM   1980 C CD  . GLU B 1 24  ? 231.680 251.801 254.674 1.00 67.27  ? 281 GLU D CD  1 
ATOM   1981 O OE1 . GLU B 1 24  ? 232.723 251.539 255.307 1.00 64.07  ? 281 GLU D OE1 1 
ATOM   1982 O OE2 . GLU B 1 24  ? 231.620 252.684 253.795 1.00 72.60  ? 281 GLU D OE2 1 
ATOM   1983 N N   . GLU B 1 25  ? 227.008 253.369 253.915 1.00 65.44  ? 282 GLU D N   1 
ATOM   1984 C CA  . GLU B 1 25  ? 226.527 254.709 254.221 1.00 56.45  ? 282 GLU D CA  1 
ATOM   1985 C C   . GLU B 1 25  ? 225.418 254.668 255.263 1.00 57.31  ? 282 GLU D C   1 
ATOM   1986 O O   . GLU B 1 25  ? 225.388 255.492 256.178 1.00 57.19  ? 282 GLU D O   1 
ATOM   1987 C CB  . GLU B 1 25  ? 226.038 255.392 252.946 1.00 55.37  ? 282 GLU D CB  1 
ATOM   1988 C CG  . GLU B 1 25  ? 227.004 256.405 252.376 1.00 60.22  ? 282 GLU D CG  1 
ATOM   1989 C CD  . GLU B 1 25  ? 226.299 257.486 251.590 1.00 68.20  ? 282 GLU D CD  1 
ATOM   1990 O OE1 . GLU B 1 25  ? 225.055 257.436 251.499 1.00 66.70  ? 282 GLU D OE1 1 
ATOM   1991 O OE2 . GLU B 1 25  ? 226.986 258.385 251.063 1.00 71.01  ? 282 GLU D OE2 1 
ATOM   1992 N N   . LEU B 1 26  ? 224.490 253.717 255.137 1.00 52.37  ? 283 LEU D N   1 
ATOM   1993 C CA  . LEU B 1 26  ? 223.428 253.605 256.132 1.00 49.31  ? 283 LEU D CA  1 
ATOM   1994 C C   . LEU B 1 26  ? 223.969 253.149 257.481 1.00 49.83  ? 283 LEU D C   1 
ATOM   1995 O O   . LEU B 1 26  ? 223.498 253.612 258.527 1.00 54.79  ? 283 LEU D O   1 
ATOM   1996 C CB  . LEU B 1 26  ? 222.338 252.654 255.642 1.00 51.94  ? 283 LEU D CB  1 
ATOM   1997 C CG  . LEU B 1 26  ? 220.924 252.940 256.154 1.00 51.62  ? 283 LEU D CG  1 
ATOM   1998 C CD1 . LEU B 1 26  ? 220.721 254.426 256.387 1.00 54.17  ? 283 LEU D CD1 1 
ATOM   1999 C CD2 . LEU B 1 26  ? 219.885 252.411 255.183 1.00 46.88  ? 283 LEU D CD2 1 
ATOM   2000 N N   . ARG B 1 27  ? 224.958 252.254 257.482 1.00 51.95  ? 284 ARG D N   1 
ATOM   2001 C CA  . ARG B 1 27  ? 225.578 251.856 258.741 1.00 53.16  ? 284 ARG D CA  1 
ATOM   2002 C C   . ARG B 1 27  ? 226.228 253.049 259.431 1.00 56.45  ? 284 ARG D C   1 
ATOM   2003 O O   . ARG B 1 27  ? 226.108 253.213 260.651 1.00 58.10  ? 284 ARG D O   1 
ATOM   2004 C CB  . ARG B 1 27  ? 226.602 250.749 258.496 1.00 57.16  ? 284 ARG D CB  1 
ATOM   2005 C CG  . ARG B 1 27  ? 227.645 250.607 259.592 1.00 55.90  ? 284 ARG D CG  1 
ATOM   2006 C CD  . ARG B 1 27  ? 227.059 249.957 260.832 1.00 52.90  ? 284 ARG D CD  1 
ATOM   2007 N NE  . ARG B 1 27  ? 226.012 249.000 260.500 1.00 54.40  ? 284 ARG D NE  1 
ATOM   2008 C CZ  . ARG B 1 27  ? 226.233 247.744 260.139 1.00 61.71  ? 284 ARG D CZ  1 
ATOM   2009 N NH1 . ARG B 1 27  ? 227.458 247.252 260.062 1.00 63.79  ? 284 ARG D NH1 1 
ATOM   2010 N NH2 . ARG B 1 27  ? 225.198 246.962 259.846 1.00 65.56  ? 284 ARG D NH2 1 
ATOM   2011 N N   . TRP B 1 28  ? 226.916 253.899 258.666 1.00 58.27  ? 285 TRP D N   1 
ATOM   2012 C CA  . TRP B 1 28  ? 227.513 255.093 259.257 1.00 54.42  ? 285 TRP D CA  1 
ATOM   2013 C C   . TRP B 1 28  ? 226.456 256.118 259.653 1.00 54.84  ? 285 TRP D C   1 
ATOM   2014 O O   . TRP B 1 28  ? 226.656 256.871 260.613 1.00 53.96  ? 285 TRP D O   1 
ATOM   2015 C CB  . TRP B 1 28  ? 228.519 255.705 258.290 1.00 56.70  ? 285 TRP D CB  1 
ATOM   2016 C CG  . TRP B 1 28  ? 229.899 255.168 258.465 1.00 59.96  ? 285 TRP D CG  1 
ATOM   2017 C CD1 . TRP B 1 28  ? 230.604 254.420 257.573 1.00 61.94  ? 285 TRP D CD1 1 
ATOM   2018 C CD2 . TRP B 1 28  ? 230.745 255.334 259.607 1.00 59.17  ? 285 TRP D CD2 1 
ATOM   2019 N NE1 . TRP B 1 28  ? 231.839 254.111 258.086 1.00 64.91  ? 285 TRP D NE1 1 
ATOM   2020 C CE2 . TRP B 1 28  ? 231.950 254.662 259.335 1.00 60.87  ? 285 TRP D CE2 1 
ATOM   2021 C CE3 . TRP B 1 28  ? 230.602 255.990 260.832 1.00 60.68  ? 285 TRP D CE3 1 
ATOM   2022 C CZ2 . TRP B 1 28  ? 233.005 254.626 260.241 1.00 59.18  ? 285 TRP D CZ2 1 
ATOM   2023 C CZ3 . TRP B 1 28  ? 231.650 255.952 261.731 1.00 60.96  ? 285 TRP D CZ3 1 
ATOM   2024 C CH2 . TRP B 1 28  ? 232.836 255.275 261.430 1.00 58.41  ? 285 TRP D CH2 1 
ATOM   2025 N N   . ARG B 1 29  ? 225.339 256.170 258.926 1.00 50.97  ? 286 ARG D N   1 
ATOM   2026 C CA  . ARG B 1 29  ? 224.223 257.021 259.319 1.00 45.13  ? 286 ARG D CA  1 
ATOM   2027 C C   . ARG B 1 29  ? 223.612 256.565 260.632 1.00 45.63  ? 286 ARG D C   1 
ATOM   2028 O O   . ARG B 1 29  ? 223.050 257.381 261.367 1.00 46.23  ? 286 ARG D O   1 
ATOM   2029 C CB  . ARG B 1 29  ? 223.149 257.024 258.232 1.00 44.62  ? 286 ARG D CB  1 
ATOM   2030 C CG  . ARG B 1 29  ? 223.422 257.956 257.077 1.00 50.56  ? 286 ARG D CG  1 
ATOM   2031 C CD  . ARG B 1 29  ? 222.408 259.079 257.049 1.00 45.33  ? 286 ARG D CD  1 
ATOM   2032 N NE  . ARG B 1 29  ? 222.379 259.764 255.764 1.00 43.18  ? 286 ARG D NE  1 
ATOM   2033 C CZ  . ARG B 1 29  ? 223.331 260.572 255.320 1.00 48.71  ? 286 ARG D CZ  1 
ATOM   2034 N NH1 . ARG B 1 29  ? 224.417 260.821 256.034 1.00 42.24  ? 286 ARG D NH1 1 
ATOM   2035 N NH2 . ARG B 1 29  ? 223.189 261.147 254.131 1.00 53.19  ? 286 ARG D NH2 1 
ATOM   2036 N N   . SER B 1 30  ? 223.686 255.268 260.925 1.00 50.50  ? 287 SER D N   1 
ATOM   2037 C CA  . SER B 1 30  ? 223.150 254.765 262.185 1.00 47.49  ? 287 SER D CA  1 
ATOM   2038 C C   . SER B 1 30  ? 223.817 255.442 263.375 1.00 47.36  ? 287 SER D C   1 
ATOM   2039 O O   . SER B 1 30  ? 223.143 255.842 264.330 1.00 53.00  ? 287 SER D O   1 
ATOM   2040 C CB  . SER B 1 30  ? 223.338 253.250 262.269 1.00 57.95  ? 287 SER D CB  1 
ATOM   2041 O OG  . SER B 1 30  ? 222.220 252.556 261.749 1.00 57.61  ? 287 SER D OG  1 
ATOM   2042 N N   . ILE B 1 31  ? 225.142 255.581 263.332 1.00 42.78  ? 288 ILE D N   1 
ATOM   2043 C CA  . ILE B 1 31  ? 225.869 256.147 264.464 1.00 43.98  ? 288 ILE D CA  1 
ATOM   2044 C C   . ILE B 1 31  ? 225.556 257.630 264.623 1.00 50.53  ? 288 ILE D C   1 
ATOM   2045 O O   . ILE B 1 31  ? 225.244 258.099 265.723 1.00 53.51  ? 288 ILE D O   1 
ATOM   2046 C CB  . ILE B 1 31  ? 227.379 255.904 264.300 1.00 44.25  ? 288 ILE D CB  1 
ATOM   2047 C CG1 . ILE B 1 31  ? 227.639 254.455 263.894 1.00 43.96  ? 288 ILE D CG1 1 
ATOM   2048 C CG2 . ILE B 1 31  ? 228.110 256.235 265.585 1.00 47.49  ? 288 ILE D CG2 1 
ATOM   2049 C CD1 . ILE B 1 31  ? 229.103 254.098 263.820 1.00 49.33  ? 288 ILE D CD1 1 
ATOM   2050 N N   . GLN B 1 32  ? 225.633 258.392 263.529 1.00 53.06  ? 289 GLN D N   1 
ATOM   2051 C CA  . GLN B 1 32  ? 225.475 259.840 263.627 1.00 46.45  ? 289 GLN D CA  1 
ATOM   2052 C C   . GLN B 1 32  ? 224.022 260.260 263.780 1.00 49.38  ? 289 GLN D C   1 
ATOM   2053 O O   . GLN B 1 32  ? 223.749 261.369 264.251 1.00 50.73  ? 289 GLN D O   1 
ATOM   2054 C CB  . GLN B 1 32  ? 226.082 260.527 262.403 1.00 42.52  ? 289 GLN D CB  1 
ATOM   2055 C CG  . GLN B 1 32  ? 225.107 260.791 261.280 1.00 46.13  ? 289 GLN D CG  1 
ATOM   2056 C CD  . GLN B 1 32  ? 225.503 261.984 260.440 1.00 44.41  ? 289 GLN D CD  1 
ATOM   2057 O OE1 . GLN B 1 32  ? 226.096 261.837 259.374 1.00 52.79  ? 289 GLN D OE1 1 
ATOM   2058 N NE2 . GLN B 1 32  ? 225.173 263.176 260.917 1.00 36.96  ? 289 GLN D NE2 1 
ATOM   2059 N N   . TYR B 1 33  ? 223.082 259.402 263.396 1.00 46.14  ? 290 TYR D N   1 
ATOM   2060 C CA  . TYR B 1 33  ? 221.679 259.774 263.424 1.00 38.98  ? 290 TYR D CA  1 
ATOM   2061 C C   . TYR B 1 33  ? 221.022 259.392 264.740 1.00 45.62  ? 290 TYR D C   1 
ATOM   2062 O O   . TYR B 1 33  ? 220.003 259.985 265.109 1.00 47.95  ? 290 TYR D O   1 
ATOM   2063 C CB  . TYR B 1 33  ? 220.961 259.114 262.249 1.00 44.07  ? 290 TYR D CB  1 
ATOM   2064 C CG  . TYR B 1 33  ? 220.675 260.068 261.117 1.00 50.48  ? 290 TYR D CG  1 
ATOM   2065 C CD1 . TYR B 1 33  ? 221.700 260.807 260.544 1.00 57.28  ? 290 TYR D CD1 1 
ATOM   2066 C CD2 . TYR B 1 33  ? 219.403 260.211 260.598 1.00 44.94  ? 290 TYR D CD2 1 
ATOM   2067 C CE1 . TYR B 1 33  ? 221.460 261.677 259.502 1.00 54.95  ? 290 TYR D CE1 1 
ATOM   2068 C CE2 . TYR B 1 33  ? 219.157 261.078 259.551 1.00 48.41  ? 290 TYR D CE2 1 
ATOM   2069 C CZ  . TYR B 1 33  ? 220.185 261.807 259.009 1.00 52.84  ? 290 TYR D CZ  1 
ATOM   2070 O OH  . TYR B 1 33  ? 219.934 262.670 257.969 1.00 54.70  ? 290 TYR D OH  1 
ATOM   2071 N N   . ALA B 1 34  ? 221.583 258.416 265.449 1.00 46.78  ? 291 ALA D N   1 
ATOM   2072 C CA  . ALA B 1 34  ? 221.197 258.115 266.818 1.00 36.98  ? 291 ALA D CA  1 
ATOM   2073 C C   . ALA B 1 34  ? 221.948 258.967 267.828 1.00 45.83  ? 291 ALA D C   1 
ATOM   2074 O O   . ALA B 1 34  ? 221.594 258.959 269.010 1.00 50.85  ? 291 ALA D O   1 
ATOM   2075 C CB  . ALA B 1 34  ? 221.426 256.632 267.122 1.00 34.19  ? 291 ALA D CB  1 
ATOM   2076 N N   . SER B 1 35  ? 222.961 259.716 267.390 1.00 47.82  ? 292 SER D N   1 
ATOM   2077 C CA  . SER B 1 35  ? 223.630 260.666 268.268 1.00 45.00  ? 292 SER D CA  1 
ATOM   2078 C C   . SER B 1 35  ? 222.712 261.798 268.702 1.00 49.65  ? 292 SER D C   1 
ATOM   2079 O O   . SER B 1 35  ? 223.060 262.539 269.626 1.00 49.26  ? 292 SER D O   1 
ATOM   2080 C CB  . SER B 1 35  ? 224.867 261.240 267.578 1.00 45.06  ? 292 SER D CB  1 
ATOM   2081 O OG  . SER B 1 35  ? 225.336 262.392 268.253 1.00 41.56  ? 292 SER D OG  1 
ATOM   2082 N N   . ARG B 1 36  ? 221.561 261.951 268.057 1.00 52.41  ? 293 ARG D N   1 
ATOM   2083 C CA  . ARG B 1 36  ? 220.566 262.936 268.443 1.00 48.98  ? 293 ARG D CA  1 
ATOM   2084 C C   . ARG B 1 36  ? 219.759 262.407 269.627 1.00 55.69  ? 293 ARG D C   1 
ATOM   2085 O O   . ARG B 1 36  ? 220.110 261.400 270.248 1.00 64.76  ? 293 ARG D O   1 
ATOM   2086 C CB  . ARG B 1 36  ? 219.684 263.276 267.246 1.00 48.96  ? 293 ARG D CB  1 
ATOM   2087 C CG  . ARG B 1 36  ? 220.455 263.848 266.075 1.00 52.50  ? 293 ARG D CG  1 
ATOM   2088 C CD  . ARG B 1 36  ? 219.548 264.113 264.898 1.00 52.85  ? 293 ARG D CD  1 
ATOM   2089 N NE  . ARG B 1 36  ? 220.304 264.460 263.702 1.00 54.05  ? 293 ARG D NE  1 
ATOM   2090 C CZ  . ARG B 1 36  ? 219.757 264.700 262.519 1.00 56.07  ? 293 ARG D CZ  1 
ATOM   2091 N NH1 . ARG B 1 36  ? 218.448 264.637 262.338 1.00 53.66  ? 293 ARG D NH1 1 
ATOM   2092 N NH2 . ARG B 1 36  ? 220.542 265.013 261.493 1.00 56.69  ? 293 ARG D NH2 1 
ATOM   2093 N N   . GLY B 1 37  ? 218.660 263.080 269.951 1.00 65.12  ? 294 GLY D N   1 
ATOM   2094 C CA  . GLY B 1 37  ? 217.893 262.707 271.122 1.00 70.37  ? 294 GLY D CA  1 
ATOM   2095 C C   . GLY B 1 37  ? 217.097 261.433 270.912 1.00 68.73  ? 294 GLY D C   1 
ATOM   2096 O O   . GLY B 1 37  ? 216.951 260.933 269.798 1.00 66.42  ? 294 GLY D O   1 
ATOM   2097 N N   . GLU B 1 38  ? 216.574 260.905 272.015 1.00 77.22  ? 295 GLU D N   1 
ATOM   2098 C CA  . GLU B 1 38  ? 215.779 259.679 271.995 1.00 76.99  ? 295 GLU D CA  1 
ATOM   2099 C C   . GLU B 1 38  ? 214.301 260.042 271.968 1.00 80.90  ? 295 GLU D C   1 
ATOM   2100 O O   . GLU B 1 38  ? 213.561 259.748 272.909 1.00 85.70  ? 295 GLU D O   1 
ATOM   2101 C CB  . GLU B 1 38  ? 216.101 258.815 273.208 1.00 76.05  ? 295 GLU D CB  1 
ATOM   2102 C CG  . GLU B 1 38  ? 217.575 258.740 273.541 1.00 82.14  ? 295 GLU D CG  1 
ATOM   2103 C CD  . GLU B 1 38  ? 218.429 258.493 272.319 1.00 84.20  ? 295 GLU D CD  1 
ATOM   2104 O OE1 . GLU B 1 38  ? 219.428 259.219 272.134 1.00 80.73  ? 295 GLU D OE1 1 
ATOM   2105 O OE2 . GLU B 1 38  ? 218.102 257.569 271.546 1.00 85.09  ? 295 GLU D OE2 1 
ATOM   2106 N N   . ARG B 1 39  ? 213.860 260.680 270.892 1.00 74.90  ? 296 ARG D N   1 
ATOM   2107 C CA  . ARG B 1 39  ? 212.456 261.040 270.716 1.00 73.27  ? 296 ARG D CA  1 
ATOM   2108 C C   . ARG B 1 39  ? 211.730 259.799 270.205 1.00 73.41  ? 296 ARG D C   1 
ATOM   2109 O O   . ARG B 1 39  ? 211.322 259.735 269.045 1.00 74.08  ? 296 ARG D O   1 
ATOM   2110 C CB  . ARG B 1 39  ? 212.278 262.229 269.760 1.00 73.54  ? 296 ARG D CB  1 
ATOM   2111 C CG  . ARG B 1 39  ? 212.602 263.609 270.341 1.00 76.62  ? 296 ARG D CG  1 
ATOM   2112 C CD  . ARG B 1 39  ? 214.044 263.749 270.794 1.00 75.88  ? 296 ARG D CD  1 
ATOM   2113 N NE  . ARG B 1 39  ? 214.978 263.328 269.758 1.00 77.09  ? 296 ARG D NE  1 
ATOM   2114 C CZ  . ARG B 1 39  ? 215.493 264.134 268.840 1.00 81.41  ? 296 ARG D CZ  1 
ATOM   2115 N NH1 . ARG B 1 39  ? 215.184 265.420 268.797 1.00 80.08  ? 296 ARG D NH1 1 
ATOM   2116 N NH2 . ARG B 1 39  ? 216.343 263.639 267.945 1.00 77.53  ? 296 ARG D NH2 1 
ATOM   2117 N N   . HIS B 1 40  ? 211.573 258.810 271.079 1.00 72.23  ? 297 HIS D N   1 
ATOM   2118 C CA  . HIS B 1 40  ? 210.849 257.586 270.755 1.00 71.86  ? 297 HIS D CA  1 
ATOM   2119 C C   . HIS B 1 40  ? 209.367 257.821 271.036 1.00 74.01  ? 297 HIS D C   1 
ATOM   2120 O O   . HIS B 1 40  ? 208.880 257.579 272.144 1.00 76.54  ? 297 HIS D O   1 
ATOM   2121 C CB  . HIS B 1 40  ? 211.437 256.385 271.506 1.00 70.67  ? 297 HIS D CB  1 
ATOM   2122 C CG  . HIS B 1 40  ? 211.221 256.397 272.990 1.00 73.68  ? 297 HIS D CG  1 
ATOM   2123 N ND1 . HIS B 1 40  ? 209.971 256.398 273.568 1.00 78.03  ? 297 HIS D ND1 1 
ATOM   2124 C CD2 . HIS B 1 40  ? 212.107 256.402 274.014 1.00 77.49  ? 297 HIS D CD2 1 
ATOM   2125 C CE1 . HIS B 1 40  ? 210.094 256.406 274.883 1.00 78.86  ? 297 HIS D CE1 1 
ATOM   2126 N NE2 . HIS B 1 40  ? 211.380 256.409 275.180 1.00 80.52  ? 297 HIS D NE2 1 
ATOM   2127 N N   . SER B 1 41  ? 208.658 258.313 270.027 1.00 68.69  ? 298 SER D N   1 
ATOM   2128 C CA  . SER B 1 41  ? 207.233 258.591 270.116 1.00 64.94  ? 298 SER D CA  1 
ATOM   2129 C C   . SER B 1 41  ? 206.651 258.392 268.727 1.00 66.69  ? 298 SER D C   1 
ATOM   2130 O O   . SER B 1 41  ? 207.382 258.364 267.733 1.00 68.74  ? 298 SER D O   1 
ATOM   2131 C CB  . SER B 1 41  ? 206.952 260.006 270.625 1.00 67.42  ? 298 SER D CB  1 
ATOM   2132 O OG  . SER B 1 41  ? 207.802 260.950 269.998 1.00 70.93  ? 298 SER D OG  1 
ATOM   2133 N N   . ALA B 1 42  ? 205.330 258.258 268.672 1.00 65.21  ? 299 ALA D N   1 
ATOM   2134 C CA  . ALA B 1 42  ? 204.629 257.897 267.444 1.00 66.56  ? 299 ALA D CA  1 
ATOM   2135 C C   . ALA B 1 42  ? 205.216 256.611 266.866 1.00 61.25  ? 299 ALA D C   1 
ATOM   2136 O O   . ALA B 1 42  ? 205.776 256.579 265.770 1.00 66.53  ? 299 ALA D O   1 
ATOM   2137 C CB  . ALA B 1 42  ? 204.670 259.039 266.424 1.00 64.47  ? 299 ALA D CB  1 
ATOM   2138 N N   . TYR B 1 43  ? 205.090 255.542 267.653 1.00 52.47  ? 300 TYR D N   1 
ATOM   2139 C CA  . TYR B 1 43  ? 205.609 254.239 267.258 1.00 54.09  ? 300 TYR D CA  1 
ATOM   2140 C C   . TYR B 1 43  ? 204.985 253.744 265.963 1.00 54.28  ? 300 TYR D C   1 
ATOM   2141 O O   . TYR B 1 43  ? 205.596 252.931 265.262 1.00 59.40  ? 300 TYR D O   1 
ATOM   2142 C CB  . TYR B 1 43  ? 205.370 253.238 268.390 1.00 59.19  ? 300 TYR D CB  1 
ATOM   2143 C CG  . TYR B 1 43  ? 205.677 251.796 268.061 1.00 61.29  ? 300 TYR D CG  1 
ATOM   2144 C CD1 . TYR B 1 43  ? 206.952 251.400 267.686 1.00 61.64  ? 300 TYR D CD1 1 
ATOM   2145 C CD2 . TYR B 1 43  ? 204.689 250.825 268.147 1.00 61.54  ? 300 TYR D CD2 1 
ATOM   2146 C CE1 . TYR B 1 43  ? 207.229 250.077 267.395 1.00 60.41  ? 300 TYR D CE1 1 
ATOM   2147 C CE2 . TYR B 1 43  ? 204.958 249.505 267.858 1.00 56.82  ? 300 TYR D CE2 1 
ATOM   2148 C CZ  . TYR B 1 43  ? 206.227 249.136 267.483 1.00 56.21  ? 300 TYR D CZ  1 
ATOM   2149 O OH  . TYR B 1 43  ? 206.489 247.819 267.197 1.00 54.45  ? 300 TYR D OH  1 
ATOM   2150 N N   . ASN B 1 44  ? 203.795 254.227 265.623 1.00 60.24  ? 301 ASN D N   1 
ATOM   2151 C CA  . ASN B 1 44  ? 203.123 253.863 264.386 1.00 62.99  ? 301 ASN D CA  1 
ATOM   2152 C C   . ASN B 1 44  ? 203.549 254.724 263.206 1.00 62.26  ? 301 ASN D C   1 
ATOM   2153 O O   . ASN B 1 44  ? 203.087 254.487 262.086 1.00 65.41  ? 301 ASN D O   1 
ATOM   2154 C CB  . ASN B 1 44  ? 201.607 253.957 264.572 1.00 63.92  ? 301 ASN D CB  1 
ATOM   2155 C CG  . ASN B 1 44  ? 201.157 253.456 265.928 1.00 66.05  ? 301 ASN D CG  1 
ATOM   2156 O OD1 . ASN B 1 44  ? 201.854 252.677 266.575 1.00 67.87  ? 301 ASN D OD1 1 
ATOM   2157 N ND2 . ASN B 1 44  ? 199.988 253.903 266.366 1.00 64.89  ? 301 ASN D ND2 1 
ATOM   2158 N N   . GLU B 1 45  ? 204.412 255.718 263.427 1.00 61.76  ? 302 GLU D N   1 
ATOM   2159 C CA  . GLU B 1 45  ? 204.847 256.574 262.328 1.00 62.33  ? 302 GLU D CA  1 
ATOM   2160 C C   . GLU B 1 45  ? 205.872 255.872 261.447 1.00 59.63  ? 302 GLU D C   1 
ATOM   2161 O O   . GLU B 1 45  ? 205.934 256.125 260.239 1.00 59.53  ? 302 GLU D O   1 
ATOM   2162 C CB  . GLU B 1 45  ? 205.417 257.883 262.874 1.00 61.74  ? 302 GLU D CB  1 
ATOM   2163 N N   . TRP B 1 46  ? 206.686 254.993 262.029 1.00 51.39  ? 303 TRP D N   1 
ATOM   2164 C CA  . TRP B 1 46  ? 207.710 254.288 261.271 1.00 50.46  ? 303 TRP D CA  1 
ATOM   2165 C C   . TRP B 1 46  ? 207.473 252.792 261.152 1.00 64.77  ? 303 TRP D C   1 
ATOM   2166 O O   . TRP B 1 46  ? 207.942 252.185 260.188 1.00 65.98  ? 303 TRP D O   1 
ATOM   2167 C CB  . TRP B 1 46  ? 209.097 254.529 261.888 1.00 48.27  ? 303 TRP D CB  1 
ATOM   2168 C CG  . TRP B 1 46  ? 209.331 253.921 263.252 1.00 53.33  ? 303 TRP D CG  1 
ATOM   2169 C CD1 . TRP B 1 46  ? 209.399 252.593 263.562 1.00 53.20  ? 303 TRP D CD1 1 
ATOM   2170 C CD2 . TRP B 1 46  ? 209.574 254.627 264.475 1.00 52.76  ? 303 TRP D CD2 1 
ATOM   2171 N NE1 . TRP B 1 46  ? 209.647 252.430 264.901 1.00 51.21  ? 303 TRP D NE1 1 
ATOM   2172 C CE2 . TRP B 1 46  ? 209.760 253.664 265.484 1.00 55.82  ? 303 TRP D CE2 1 
ATOM   2173 C CE3 . TRP B 1 46  ? 209.642 255.980 264.816 1.00 55.08  ? 303 TRP D CE3 1 
ATOM   2174 C CZ2 . TRP B 1 46  ? 210.010 254.009 266.810 1.00 55.18  ? 303 TRP D CZ2 1 
ATOM   2175 C CZ3 . TRP B 1 46  ? 209.892 256.321 266.134 1.00 55.23  ? 303 TRP D CZ3 1 
ATOM   2176 C CH2 . TRP B 1 46  ? 210.072 255.340 267.113 1.00 48.54  ? 303 TRP D CH2 1 
ATOM   2177 N N   . LYS B 1 47  ? 206.757 252.182 262.100 1.00 77.84  ? 304 LYS D N   1 
ATOM   2178 C CA  . LYS B 1 47  ? 206.611 250.731 262.101 1.00 71.73  ? 304 LYS D CA  1 
ATOM   2179 C C   . LYS B 1 47  ? 205.745 250.229 260.956 1.00 72.58  ? 304 LYS D C   1 
ATOM   2180 O O   . LYS B 1 47  ? 205.742 249.024 260.684 1.00 75.30  ? 304 LYS D O   1 
ATOM   2181 C CB  . LYS B 1 47  ? 206.028 250.257 263.431 1.00 64.60  ? 304 LYS D CB  1 
ATOM   2182 C CG  . LYS B 1 47  ? 204.519 250.362 263.517 1.00 64.24  ? 304 LYS D CG  1 
ATOM   2183 C CD  . LYS B 1 47  ? 203.884 249.003 263.732 1.00 70.02  ? 304 LYS D CD  1 
ATOM   2184 C CE  . LYS B 1 47  ? 202.389 249.127 263.970 1.00 72.86  ? 304 LYS D CE  1 
ATOM   2185 N NZ  . LYS B 1 47  ? 201.763 247.809 264.266 1.00 71.14  ? 304 LYS D NZ  1 
ATOM   2186 N N   . LYS B 1 48  ? 205.013 251.113 260.281 1.00 64.28  ? 305 LYS D N   1 
ATOM   2187 C CA  . LYS B 1 48  ? 204.173 250.702 259.167 1.00 64.91  ? 305 LYS D CA  1 
ATOM   2188 C C   . LYS B 1 48  ? 204.710 251.133 257.811 1.00 65.39  ? 305 LYS D C   1 
ATOM   2189 O O   . LYS B 1 48  ? 204.388 250.491 256.806 1.00 72.67  ? 305 LYS D O   1 
ATOM   2190 C CB  . LYS B 1 48  ? 202.752 251.250 259.342 1.00 62.75  ? 305 LYS D CB  1 
ATOM   2191 C CG  . LYS B 1 48  ? 202.624 252.741 259.113 1.00 61.29  ? 305 LYS D CG  1 
ATOM   2192 C CD  . LYS B 1 48  ? 201.176 253.177 259.182 1.00 65.73  ? 305 LYS D CD  1 
ATOM   2193 C CE  . LYS B 1 48  ? 200.640 253.066 260.596 1.00 66.97  ? 305 LYS D CE  1 
ATOM   2194 N NZ  . LYS B 1 48  ? 200.903 254.305 261.376 1.00 67.46  ? 305 LYS D NZ  1 
ATOM   2195 N N   . ALA B 1 49  ? 205.518 252.190 257.754 1.00 47.47  ? 306 ALA D N   1 
ATOM   2196 C CA  . ALA B 1 49  ? 206.012 252.694 256.479 1.00 51.30  ? 306 ALA D CA  1 
ATOM   2197 C C   . ALA B 1 49  ? 207.344 252.064 256.094 1.00 55.37  ? 306 ALA D C   1 
ATOM   2198 O O   . ALA B 1 49  ? 207.496 251.560 254.978 1.00 62.92  ? 306 ALA D O   1 
ATOM   2199 C CB  . ALA B 1 49  ? 206.143 254.218 256.532 1.00 57.32  ? 306 ALA D CB  1 
ATOM   2200 N N   . LEU B 1 50  ? 208.319 252.090 257.003 1.00 49.47  ? 307 LEU D N   1 
ATOM   2201 C CA  . LEU B 1 50  ? 209.616 251.489 256.722 1.00 52.60  ? 307 LEU D CA  1 
ATOM   2202 C C   . LEU B 1 50  ? 209.529 249.970 256.632 1.00 61.88  ? 307 LEU D C   1 
ATOM   2203 O O   . LEU B 1 50  ? 210.167 249.360 255.767 1.00 53.38  ? 307 LEU D O   1 
ATOM   2204 C CB  . LEU B 1 50  ? 210.624 251.898 257.794 1.00 53.45  ? 307 LEU D CB  1 
ATOM   2205 C CG  . LEU B 1 50  ? 211.696 252.893 257.362 1.00 53.85  ? 307 LEU D CG  1 
ATOM   2206 C CD1 . LEU B 1 50  ? 212.705 253.092 258.474 1.00 55.12  ? 307 LEU D CD1 1 
ATOM   2207 C CD2 . LEU B 1 50  ? 212.376 252.410 256.098 1.00 55.38  ? 307 LEU D CD2 1 
ATOM   2208 N N   . PHE B 1 51  ? 208.745 249.348 257.510 1.00 74.82  ? 308 PHE D N   1 
ATOM   2209 C CA  . PHE B 1 51  ? 208.659 247.899 257.623 1.00 69.10  ? 308 PHE D CA  1 
ATOM   2210 C C   . PHE B 1 51  ? 207.274 247.420 257.208 1.00 64.84  ? 308 PHE D C   1 
ATOM   2211 O O   . PHE B 1 51  ? 206.264 248.032 257.569 1.00 68.23  ? 308 PHE D O   1 
ATOM   2212 C CB  . PHE B 1 51  ? 208.957 247.451 259.055 1.00 59.89  ? 308 PHE D CB  1 
ATOM   2213 C CG  . PHE B 1 51  ? 210.417 247.462 259.398 1.00 61.56  ? 308 PHE D CG  1 
ATOM   2214 C CD1 . PHE B 1 51  ? 211.361 247.081 258.467 1.00 60.88  ? 308 PHE D CD1 1 
ATOM   2215 C CD2 . PHE B 1 51  ? 210.846 247.853 260.649 1.00 65.24  ? 308 PHE D CD2 1 
ATOM   2216 C CE1 . PHE B 1 51  ? 212.706 247.088 258.777 1.00 60.81  ? 308 PHE D CE1 1 
ATOM   2217 C CE2 . PHE B 1 51  ? 212.191 247.859 260.962 1.00 68.85  ? 308 PHE D CE2 1 
ATOM   2218 C CZ  . PHE B 1 51  ? 213.120 247.478 260.024 1.00 64.78  ? 308 PHE D CZ  1 
ATOM   2219 N N   . LYS B 1 52  ? 207.229 246.323 256.451 1.00 63.66  ? 309 LYS D N   1 
ATOM   2220 C CA  . LYS B 1 52  ? 205.865 245.959 256.085 1.00 72.38  ? 309 LYS D CA  1 
ATOM   2221 C C   . LYS B 1 52  ? 205.347 244.843 256.988 1.00 68.89  ? 309 LYS D C   1 
ATOM   2222 O O   . LYS B 1 52  ? 206.121 243.983 257.416 1.00 66.81  ? 309 LYS D O   1 
ATOM   2223 C CB  . LYS B 1 52  ? 205.788 245.509 254.629 1.00 78.44  ? 309 LYS D CB  1 
ATOM   2224 C CG  . LYS B 1 52  ? 206.914 244.601 254.183 1.00 78.12  ? 309 LYS D CG  1 
ATOM   2225 C CD  . LYS B 1 52  ? 207.292 244.877 252.738 1.00 79.11  ? 309 LYS D CD  1 
ATOM   2226 C CE  . LYS B 1 52  ? 208.678 244.352 252.422 1.00 78.69  ? 309 LYS D CE  1 
ATOM   2227 N NZ  . LYS B 1 52  ? 209.705 245.012 253.269 1.00 72.07  ? 309 LYS D NZ  1 
ATOM   2228 N N   . PRO B 1 53  ? 204.048 244.848 257.281 1.00 72.32  ? 310 PRO D N   1 
ATOM   2229 C CA  . PRO B 1 53  ? 203.497 243.846 258.198 1.00 75.00  ? 310 PRO D CA  1 
ATOM   2230 C C   . PRO B 1 53  ? 203.582 242.439 257.631 1.00 75.12  ? 310 PRO D C   1 
ATOM   2231 O O   . PRO B 1 53  ? 203.534 242.225 256.418 1.00 78.03  ? 310 PRO D O   1 
ATOM   2232 C CB  . PRO B 1 53  ? 202.040 244.290 258.375 1.00 74.28  ? 310 PRO D CB  1 
ATOM   2233 C CG  . PRO B 1 53  ? 201.745 245.118 257.178 1.00 70.43  ? 310 PRO D CG  1 
ATOM   2234 C CD  . PRO B 1 53  ? 203.026 245.811 256.839 1.00 72.91  ? 310 PRO D CD  1 
ATOM   2235 N N   . ALA B 1 54  ? 203.717 241.473 258.537 1.00 66.07  ? 311 ALA D N   1 
ATOM   2236 C CA  . ALA B 1 54  ? 203.708 240.059 258.195 1.00 66.13  ? 311 ALA D CA  1 
ATOM   2237 C C   . ALA B 1 54  ? 202.718 239.344 259.100 1.00 69.62  ? 311 ALA D C   1 
ATOM   2238 O O   . ALA B 1 54  ? 202.800 239.460 260.326 1.00 72.96  ? 311 ALA D O   1 
ATOM   2239 C CB  . ALA B 1 54  ? 205.102 239.442 258.337 1.00 66.31  ? 311 ALA D CB  1 
ATOM   2240 N N   . ASP B 1 55  ? 201.785 238.612 258.497 1.00 79.50  ? 312 ASP D N   1 
ATOM   2241 C CA  . ASP B 1 55  ? 200.801 237.832 259.245 1.00 81.40  ? 312 ASP D CA  1 
ATOM   2242 C C   . ASP B 1 55  ? 201.439 236.468 259.469 1.00 82.38  ? 312 ASP D C   1 
ATOM   2243 O O   . ASP B 1 55  ? 201.626 235.694 258.528 1.00 84.11  ? 312 ASP D O   1 
ATOM   2244 C CB  . ASP B 1 55  ? 199.484 237.750 258.475 1.00 79.84  ? 312 ASP D CB  1 
ATOM   2245 C CG  . ASP B 1 55  ? 198.601 236.571 258.892 1.00 82.07  ? 312 ASP D CG  1 
ATOM   2246 O OD1 . ASP B 1 55  ? 198.840 235.926 259.935 1.00 81.60  ? 312 ASP D OD1 1 
ATOM   2247 O OD2 . ASP B 1 55  ? 197.638 236.288 258.149 1.00 83.33  ? 312 ASP D OD2 1 
ATOM   2248 N N   . VAL B 1 56  ? 201.776 236.172 260.719 1.00 66.10  ? 313 VAL D N   1 
ATOM   2249 C CA  . VAL B 1 56  ? 202.511 234.959 261.055 1.00 59.45  ? 313 VAL D CA  1 
ATOM   2250 C C   . VAL B 1 56  ? 201.505 233.859 261.367 1.00 62.59  ? 313 VAL D C   1 
ATOM   2251 O O   . VAL B 1 56  ? 200.856 233.871 262.416 1.00 64.88  ? 313 VAL D O   1 
ATOM   2252 C CB  . VAL B 1 56  ? 203.470 235.189 262.228 1.00 58.61  ? 313 VAL D CB  1 
ATOM   2253 C CG1 . VAL B 1 56  ? 204.059 233.871 262.694 1.00 63.04  ? 313 VAL D CG1 1 
ATOM   2254 C CG2 . VAL B 1 56  ? 204.572 236.146 261.819 1.00 64.39  ? 313 VAL D CG2 1 
ATOM   2255 N N   . ILE B 1 57  ? 201.367 232.916 260.445 1.00 66.13  ? 314 ILE D N   1 
ATOM   2256 C CA  . ILE B 1 57  ? 200.653 231.674 260.700 1.00 65.22  ? 314 ILE D CA  1 
ATOM   2257 C C   . ILE B 1 57  ? 201.650 230.689 261.297 1.00 64.82  ? 314 ILE D C   1 
ATOM   2258 O O   . ILE B 1 57  ? 202.784 230.562 260.816 1.00 59.93  ? 314 ILE D O   1 
ATOM   2259 C CB  . ILE B 1 57  ? 199.994 231.136 259.411 1.00 65.55  ? 314 ILE D CB  1 
ATOM   2260 C CG1 . ILE B 1 57  ? 198.669 230.425 259.704 1.00 66.42  ? 314 ILE D CG1 1 
ATOM   2261 C CG2 . ILE B 1 57  ? 200.906 230.225 258.617 1.00 59.45  ? 314 ILE D CG2 1 
ATOM   2262 C CD1 . ILE B 1 57  ? 197.661 231.250 260.442 1.00 67.86  ? 314 ILE D CD1 1 
ATOM   2263 N N   . LEU B 1 58  ? 201.268 230.059 262.401 1.00 68.38  ? 315 LEU D N   1 
ATOM   2264 C CA  . LEU B 1 58  ? 202.137 229.072 263.019 1.00 63.47  ? 315 LEU D CA  1 
ATOM   2265 C C   . LEU B 1 58  ? 202.034 227.752 262.272 1.00 66.20  ? 315 LEU D C   1 
ATOM   2266 O O   . LEU B 1 58  ? 201.077 227.501 261.535 1.00 71.25  ? 315 LEU D O   1 
ATOM   2267 C CB  . LEU B 1 58  ? 201.789 228.877 264.493 1.00 60.67  ? 315 LEU D CB  1 
ATOM   2268 C CG  . LEU B 1 58  ? 202.619 229.718 265.463 1.00 65.11  ? 315 LEU D CG  1 
ATOM   2269 C CD1 . LEU B 1 58  ? 202.276 229.377 266.901 1.00 63.51  ? 315 LEU D CD1 1 
ATOM   2270 C CD2 . LEU B 1 58  ? 204.099 229.509 265.200 1.00 56.99  ? 315 LEU D CD2 1 
ATOM   2271 N N   . ASP B 1 59  ? 203.037 226.907 262.467 1.00 55.46  ? 316 ASP D N   1 
ATOM   2272 C CA  . ASP B 1 59  ? 203.136 225.661 261.719 1.00 48.17  ? 316 ASP D CA  1 
ATOM   2273 C C   . ASP B 1 59  ? 202.937 224.548 262.736 1.00 54.94  ? 316 ASP D C   1 
ATOM   2274 O O   . ASP B 1 59  ? 203.885 224.179 263.446 1.00 61.03  ? 316 ASP D O   1 
ATOM   2275 C CB  . ASP B 1 59  ? 204.508 225.571 261.031 1.00 51.94  ? 316 ASP D CB  1 
ATOM   2276 C CG  . ASP B 1 59  ? 204.925 224.155 260.635 1.00 60.42  ? 316 ASP D CG  1 
ATOM   2277 O OD1 . ASP B 1 59  ? 204.201 223.170 260.864 1.00 69.10  ? 316 ASP D OD1 1 
ATOM   2278 O OD2 . ASP B 1 59  ? 205.994 224.044 260.000 1.00 58.51  ? 316 ASP D OD2 1 
ATOM   2279 N N   . PRO B 1 60  ? 201.730 223.988 262.860 1.00 56.96  ? 317 PRO D N   1 
ATOM   2280 C CA  . PRO B 1 60  ? 201.502 222.962 263.884 1.00 54.99  ? 317 PRO D CA  1 
ATOM   2281 C C   . PRO B 1 60  ? 202.023 221.606 263.448 1.00 51.44  ? 317 PRO D C   1 
ATOM   2282 O O   . PRO B 1 60  ? 201.361 220.581 263.638 1.00 59.59  ? 317 PRO D O   1 
ATOM   2283 C CB  . PRO B 1 60  ? 199.974 222.947 264.042 1.00 56.90  ? 317 PRO D CB  1 
ATOM   2284 C CG  . PRO B 1 60  ? 199.439 224.009 263.096 1.00 58.40  ? 317 PRO D CG  1 
ATOM   2285 C CD  . PRO B 1 60  ? 200.510 224.281 262.097 1.00 56.13  ? 317 PRO D CD  1 
ATOM   2286 N N   . LYS B 1 61  ? 203.211 221.596 262.861 1.00 45.83  ? 318 LYS D N   1 
ATOM   2287 C CA  . LYS B 1 61  ? 203.878 220.356 262.488 1.00 49.12  ? 318 LYS D CA  1 
ATOM   2288 C C   . LYS B 1 61  ? 205.351 220.354 262.881 1.00 48.52  ? 318 LYS D C   1 
ATOM   2289 O O   . LYS B 1 61  ? 205.887 219.290 263.204 1.00 59.55  ? 318 LYS D O   1 
ATOM   2290 C CB  . LYS B 1 61  ? 203.720 220.141 260.966 1.00 48.12  ? 318 LYS D CB  1 
ATOM   2291 C CG  . LYS B 1 61  ? 204.577 219.112 260.224 1.00 52.21  ? 318 LYS D CG  1 
ATOM   2292 C CD  . LYS B 1 61  ? 204.743 217.800 260.973 1.00 58.04  ? 318 LYS D CD  1 
ATOM   2293 C CE  . LYS B 1 61  ? 205.138 216.682 260.033 1.00 60.61  ? 318 LYS D CE  1 
ATOM   2294 N NZ  . LYS B 1 61  ? 205.090 215.355 260.704 1.00 54.57  ? 318 LYS D NZ  1 
ATOM   2295 N N   . THR B 1 62  ? 206.006 221.513 262.948 1.00 39.88  ? 319 THR D N   1 
ATOM   2296 C CA  . THR B 1 62  ? 207.382 221.631 263.409 1.00 43.31  ? 319 THR D CA  1 
ATOM   2297 C C   . THR B 1 62  ? 207.481 221.810 264.918 1.00 46.07  ? 319 THR D C   1 
ATOM   2298 O O   . THR B 1 62  ? 208.590 221.922 265.448 1.00 54.50  ? 319 THR D O   1 
ATOM   2299 C CB  . THR B 1 62  ? 208.074 222.803 262.712 1.00 45.55  ? 319 THR D CB  1 
ATOM   2300 O OG1 . THR B 1 62  ? 207.184 223.924 262.670 1.00 45.68  ? 319 THR D OG1 1 
ATOM   2301 C CG2 . THR B 1 62  ? 208.459 222.429 261.295 1.00 49.27  ? 319 THR D CG2 1 
ATOM   2302 N N   . ALA B 1 63  ? 206.354 221.845 265.618 1.00 44.74  ? 320 ALA D N   1 
ATOM   2303 C CA  . ALA B 1 63  ? 206.336 222.083 267.052 1.00 48.45  ? 320 ALA D CA  1 
ATOM   2304 C C   . ALA B 1 63  ? 206.773 220.846 267.824 1.00 38.27  ? 320 ALA D C   1 
ATOM   2305 O O   . ALA B 1 63  ? 206.684 219.718 267.336 1.00 46.36  ? 320 ALA D O   1 
ATOM   2306 C CB  . ALA B 1 63  ? 204.939 222.507 267.508 1.00 52.72  ? 320 ALA D CB  1 
ATOM   2307 N N   . ASN B 1 64  ? 207.247 221.075 269.045 1.00 35.63  ? 321 ASN D N   1 
ATOM   2308 C CA  . ASN B 1 64  ? 207.548 219.980 269.949 1.00 41.82  ? 321 ASN D CA  1 
ATOM   2309 C C   . ASN B 1 64  ? 206.257 219.245 270.309 1.00 49.46  ? 321 ASN D C   1 
ATOM   2310 O O   . ASN B 1 64  ? 205.181 219.849 270.343 1.00 48.56  ? 321 ASN D O   1 
ATOM   2311 C CB  . ASN B 1 64  ? 208.221 220.508 271.214 1.00 47.19  ? 321 ASN D CB  1 
ATOM   2312 C CG  . ASN B 1 64  ? 209.365 219.636 271.674 1.00 50.90  ? 321 ASN D CG  1 
ATOM   2313 O OD1 . ASN B 1 64  ? 210.119 219.105 270.864 1.00 52.58  ? 321 ASN D OD1 1 
ATOM   2314 N ND2 . ASN B 1 64  ? 209.501 219.484 272.984 1.00 54.07  ? 321 ASN D ND2 1 
ATOM   2315 N N   . PRO B 1 65  ? 206.331 217.937 270.576 1.00 56.82  ? 322 PRO D N   1 
ATOM   2316 C CA  . PRO B 1 65  ? 205.117 217.189 270.931 1.00 52.54  ? 322 PRO D CA  1 
ATOM   2317 C C   . PRO B 1 65  ? 204.463 217.699 272.205 1.00 54.17  ? 322 PRO D C   1 
ATOM   2318 O O   . PRO B 1 65  ? 203.277 217.458 272.445 1.00 55.33  ? 322 PRO D O   1 
ATOM   2319 C CB  . PRO B 1 65  ? 205.628 215.753 271.099 1.00 44.98  ? 322 PRO D CB  1 
ATOM   2320 C CG  . PRO B 1 65  ? 206.871 215.696 270.291 1.00 42.59  ? 322 PRO D CG  1 
ATOM   2321 C CD  . PRO B 1 65  ? 207.496 217.051 270.421 1.00 50.59  ? 322 PRO D CD  1 
ATOM   2322 N N   . ILE B 1 66  ? 205.234 218.412 273.026 1.00 50.99  ? 323 ILE D N   1 
ATOM   2323 C CA  . ILE B 1 66  ? 204.741 218.947 274.290 1.00 49.97  ? 323 ILE D CA  1 
ATOM   2324 C C   . ILE B 1 66  ? 203.853 220.176 274.106 1.00 55.29  ? 323 ILE D C   1 
ATOM   2325 O O   . ILE B 1 66  ? 203.109 220.533 275.033 1.00 54.77  ? 323 ILE D O   1 
ATOM   2326 C CB  . ILE B 1 66  ? 205.928 219.275 275.223 1.00 47.59  ? 323 ILE D CB  1 
ATOM   2327 C CG1 . ILE B 1 66  ? 205.462 219.628 276.636 1.00 51.08  ? 323 ILE D CG1 1 
ATOM   2328 C CG2 . ILE B 1 66  ? 206.756 220.397 274.636 1.00 55.23  ? 323 ILE D CG2 1 
ATOM   2329 C CD1 . ILE B 1 66  ? 204.589 218.581 277.264 1.00 50.94  ? 323 ILE D CD1 1 
ATOM   2330 N N   . LEU B 1 67  ? 203.875 220.809 272.937 1.00 55.73  ? 324 LEU D N   1 
ATOM   2331 C CA  . LEU B 1 67  ? 203.190 222.076 272.718 1.00 50.90  ? 324 LEU D CA  1 
ATOM   2332 C C   . LEU B 1 67  ? 201.839 221.870 272.045 1.00 53.71  ? 324 LEU D C   1 
ATOM   2333 O O   . LEU B 1 67  ? 201.718 221.106 271.084 1.00 56.33  ? 324 LEU D O   1 
ATOM   2334 C CB  . LEU B 1 67  ? 204.048 223.011 271.866 1.00 51.00  ? 324 LEU D CB  1 
ATOM   2335 C CG  . LEU B 1 67  ? 205.402 223.403 272.455 1.00 51.78  ? 324 LEU D CG  1 
ATOM   2336 C CD1 . LEU B 1 67  ? 206.257 224.093 271.410 1.00 48.51  ? 324 LEU D CD1 1 
ATOM   2337 C CD2 . LEU B 1 67  ? 205.216 224.294 273.669 1.00 56.81  ? 324 LEU D CD2 1 
ATOM   2338 N N   . LEU B 1 68  ? 200.826 222.563 272.558 1.00 55.35  ? 325 LEU D N   1 
ATOM   2339 C CA  . LEU B 1 68  ? 199.501 222.614 271.958 1.00 52.65  ? 325 LEU D CA  1 
ATOM   2340 C C   . LEU B 1 68  ? 199.358 223.938 271.220 1.00 63.14  ? 325 LEU D C   1 
ATOM   2341 O O   . LEU B 1 68  ? 199.659 225.000 271.779 1.00 70.62  ? 325 LEU D O   1 
ATOM   2342 C CB  . LEU B 1 68  ? 198.412 222.482 273.022 1.00 51.70  ? 325 LEU D CB  1 
ATOM   2343 C CG  . LEU B 1 68  ? 197.793 221.103 273.234 1.00 66.77  ? 325 LEU D CG  1 
ATOM   2344 C CD1 . LEU B 1 68  ? 197.093 221.042 274.581 1.00 64.39  ? 325 LEU D CD1 1 
ATOM   2345 C CD2 . LEU B 1 68  ? 196.825 220.777 272.110 1.00 66.46  ? 325 LEU D CD2 1 
ATOM   2346 N N   . VAL B 1 69  ? 198.909 223.871 269.971 1.00 55.41  ? 326 VAL D N   1 
ATOM   2347 C CA  . VAL B 1 69  ? 198.694 225.043 269.134 1.00 53.37  ? 326 VAL D CA  1 
ATOM   2348 C C   . VAL B 1 69  ? 197.223 225.086 268.755 1.00 54.22  ? 326 VAL D C   1 
ATOM   2349 O O   . VAL B 1 69  ? 196.675 224.090 268.270 1.00 58.05  ? 326 VAL D O   1 
ATOM   2350 C CB  . VAL B 1 69  ? 199.581 225.017 267.875 1.00 50.22  ? 326 VAL D CB  1 
ATOM   2351 C CG1 . VAL B 1 69  ? 199.420 226.305 267.089 1.00 56.92  ? 326 VAL D CG1 1 
ATOM   2352 C CG2 . VAL B 1 69  ? 201.037 224.793 268.247 1.00 48.37  ? 326 VAL D CG2 1 
ATOM   2353 N N   . SER B 1 70  ? 196.586 226.232 268.979 1.00 65.26  ? 327 SER D N   1 
ATOM   2354 C CA  . SER B 1 70  ? 195.186 226.378 268.622 1.00 65.39  ? 327 SER D CA  1 
ATOM   2355 C C   . SER B 1 70  ? 195.010 226.261 267.110 1.00 72.08  ? 327 SER D C   1 
ATOM   2356 O O   . SER B 1 70  ? 195.953 226.415 266.329 1.00 77.39  ? 327 SER D O   1 
ATOM   2357 C CB  . SER B 1 70  ? 194.641 227.717 269.114 1.00 71.44  ? 327 SER D CB  1 
ATOM   2358 O OG  . SER B 1 70  ? 193.563 228.148 268.303 1.00 70.82  ? 327 SER D OG  1 
ATOM   2359 N N   . GLU B 1 71  ? 193.771 225.982 266.701 1.00 94.60  ? 328 GLU D N   1 
ATOM   2360 C CA  . GLU B 1 71  ? 193.480 225.768 265.288 1.00 100.03 ? 328 GLU D CA  1 
ATOM   2361 C C   . GLU B 1 71  ? 193.778 226.996 264.439 1.00 93.78  ? 328 GLU D C   1 
ATOM   2362 O O   . GLU B 1 71  ? 193.974 226.864 263.226 1.00 93.13  ? 328 GLU D O   1 
ATOM   2363 C CB  . GLU B 1 71  ? 192.017 225.357 265.112 1.00 99.98  ? 328 GLU D CB  1 
ATOM   2364 C CG  . GLU B 1 71  ? 191.024 226.278 265.806 1.00 101.70 ? 328 GLU D CG  1 
ATOM   2365 C CD  . GLU B 1 71  ? 190.721 225.850 267.229 1.00 100.02 ? 328 GLU D CD  1 
ATOM   2366 O OE1 . GLU B 1 71  ? 191.638 225.344 267.911 1.00 96.05  ? 328 GLU D OE1 1 
ATOM   2367 O OE2 . GLU B 1 71  ? 189.564 226.022 267.668 1.00 98.38  ? 328 GLU D OE2 1 
ATOM   2368 N N   . ASP B 1 72  ? 193.820 228.180 265.041 1.00 72.66  ? 329 ASP D N   1 
ATOM   2369 C CA  . ASP B 1 72  ? 194.104 229.408 264.315 1.00 77.34  ? 329 ASP D CA  1 
ATOM   2370 C C   . ASP B 1 72  ? 195.585 229.757 264.297 1.00 83.41  ? 329 ASP D C   1 
ATOM   2371 O O   . ASP B 1 72  ? 195.952 230.799 263.744 1.00 87.27  ? 329 ASP D O   1 
ATOM   2372 C CB  . ASP B 1 72  ? 193.304 230.566 264.914 1.00 77.68  ? 329 ASP D CB  1 
ATOM   2373 C CG  . ASP B 1 72  ? 191.816 230.296 264.918 1.00 78.83  ? 329 ASP D CG  1 
ATOM   2374 O OD1 . ASP B 1 72  ? 191.339 229.600 263.998 1.00 77.74  ? 329 ASP D OD1 1 
ATOM   2375 O OD2 . ASP B 1 72  ? 191.124 230.780 265.837 1.00 83.40  ? 329 ASP D OD2 1 
ATOM   2376 N N   . GLN B 1 73  ? 196.437 228.916 264.890 1.00 72.13  ? 330 GLN D N   1 
ATOM   2377 C CA  . GLN B 1 73  ? 197.890 229.089 264.854 1.00 69.72  ? 330 GLN D CA  1 
ATOM   2378 C C   . GLN B 1 73  ? 198.329 230.415 265.473 1.00 69.51  ? 330 GLN D C   1 
ATOM   2379 O O   . GLN B 1 73  ? 199.350 230.988 265.087 1.00 66.92  ? 330 GLN D O   1 
ATOM   2380 C CB  . GLN B 1 73  ? 198.423 228.944 263.427 1.00 60.47  ? 330 GLN D CB  1 
ATOM   2381 C CG  . GLN B 1 73  ? 198.111 227.596 262.798 1.00 62.68  ? 330 GLN D CG  1 
ATOM   2382 C CD  . GLN B 1 73  ? 196.737 227.540 262.165 1.00 66.52  ? 330 GLN D CD  1 
ATOM   2383 O OE1 . GLN B 1 73  ? 196.245 228.532 261.630 1.00 68.15  ? 330 GLN D OE1 1 
ATOM   2384 N NE2 . GLN B 1 73  ? 196.105 226.376 262.230 1.00 69.81  ? 330 GLN D NE2 1 
ATOM   2385 N N   . ARG B 1 74  ? 197.552 230.902 266.438 1.00 70.37  ? 331 ARG D N   1 
ATOM   2386 C CA  . ARG B 1 74  ? 197.920 232.031 267.288 1.00 69.97  ? 331 ARG D CA  1 
ATOM   2387 C C   . ARG B 1 74  ? 198.715 231.592 268.513 1.00 73.29  ? 331 ARG D C   1 
ATOM   2388 O O   . ARG B 1 74  ? 199.865 232.003 268.696 1.00 76.78  ? 331 ARG D O   1 
ATOM   2389 C CB  . ARG B 1 74  ? 196.652 232.782 267.713 1.00 73.60  ? 331 ARG D CB  1 
ATOM   2390 C CG  . ARG B 1 74  ? 195.667 233.084 266.590 1.00 72.82  ? 331 ARG D CG  1 
ATOM   2391 C CD  . ARG B 1 74  ? 196.318 233.959 265.516 1.00 71.64  ? 331 ARG D CD  1 
ATOM   2392 N NE  . ARG B 1 74  ? 197.168 233.273 264.554 1.00 74.46  ? 331 ARG D NE  1 
ATOM   2393 C CZ  . ARG B 1 74  ? 197.661 233.849 263.466 1.00 77.72  ? 331 ARG D CZ  1 
ATOM   2394 N NH1 . ARG B 1 74  ? 197.336 235.088 263.133 1.00 72.51  ? 331 ARG D NH1 1 
ATOM   2395 N NH2 . ARG B 1 74  ? 198.519 233.177 262.708 1.00 77.01  ? 331 ARG D NH2 1 
ATOM   2396 N N   . SER B 1 75  ? 198.122 230.751 269.350 1.00 66.76  ? 332 SER D N   1 
ATOM   2397 C CA  . SER B 1 75  ? 198.675 230.446 270.658 1.00 60.85  ? 332 SER D CA  1 
ATOM   2398 C C   . SER B 1 75  ? 199.438 229.130 270.639 1.00 62.47  ? 332 SER D C   1 
ATOM   2399 O O   . SER B 1 75  ? 199.012 228.148 270.027 1.00 68.51  ? 332 SER D O   1 
ATOM   2400 C CB  . SER B 1 75  ? 197.570 230.384 271.713 1.00 61.54  ? 332 SER D CB  1 
ATOM   2401 O OG  . SER B 1 75  ? 196.860 231.606 271.778 1.00 68.42  ? 332 SER D OG  1 
ATOM   2402 N N   . VAL B 1 76  ? 200.579 229.129 271.316 1.00 59.86  ? 333 VAL D N   1 
ATOM   2403 C CA  . VAL B 1 76  ? 201.335 227.921 271.610 1.00 59.08  ? 333 VAL D CA  1 
ATOM   2404 C C   . VAL B 1 76  ? 201.474 227.832 273.121 1.00 61.50  ? 333 VAL D C   1 
ATOM   2405 O O   . VAL B 1 76  ? 201.835 228.815 273.777 1.00 72.76  ? 333 VAL D O   1 
ATOM   2406 C CB  . VAL B 1 76  ? 202.715 227.916 270.915 1.00 58.50  ? 333 VAL D CB  1 
ATOM   2407 C CG1 . VAL B 1 76  ? 203.447 229.226 271.152 1.00 60.83  ? 333 VAL D CG1 1 
ATOM   2408 C CG2 . VAL B 1 76  ? 203.549 226.746 271.399 1.00 56.93  ? 333 VAL D CG2 1 
ATOM   2409 N N   . GLN B 1 77  ? 201.147 226.672 273.682 1.00 49.81  ? 334 GLN D N   1 
ATOM   2410 C CA  . GLN B 1 77  ? 201.140 226.531 275.131 1.00 50.85  ? 334 GLN D CA  1 
ATOM   2411 C C   . GLN B 1 77  ? 201.667 225.156 275.510 1.00 62.24  ? 334 GLN D C   1 
ATOM   2412 O O   . GLN B 1 77  ? 201.329 224.161 274.869 1.00 66.60  ? 334 GLN D O   1 
ATOM   2413 C CB  . GLN B 1 77  ? 199.731 226.739 275.689 1.00 46.84  ? 334 GLN D CB  1 
ATOM   2414 C CG  . GLN B 1 77  ? 199.685 227.147 277.142 1.00 53.09  ? 334 GLN D CG  1 
ATOM   2415 C CD  . GLN B 1 77  ? 198.268 227.308 277.640 1.00 59.46  ? 334 GLN D CD  1 
ATOM   2416 O OE1 . GLN B 1 77  ? 197.313 227.166 276.878 1.00 54.30  ? 334 GLN D OE1 1 
ATOM   2417 N NE2 . GLN B 1 77  ? 198.121 227.607 278.923 1.00 69.52  ? 334 GLN D NE2 1 
ATOM   2418 N N   . ARG B 1 78  ? 202.487 225.102 276.555 1.00 52.03  ? 335 ARG D N   1 
ATOM   2419 C CA  . ARG B 1 78  ? 203.079 223.837 276.974 1.00 47.61  ? 335 ARG D CA  1 
ATOM   2420 C C   . ARG B 1 78  ? 202.005 222.952 277.593 1.00 52.07  ? 335 ARG D C   1 
ATOM   2421 O O   . ARG B 1 78  ? 201.437 223.292 278.635 1.00 55.57  ? 335 ARG D O   1 
ATOM   2422 C CB  . ARG B 1 78  ? 204.216 224.078 277.962 1.00 46.23  ? 335 ARG D CB  1 
ATOM   2423 C CG  . ARG B 1 78  ? 205.284 223.003 277.946 1.00 48.23  ? 335 ARG D CG  1 
ATOM   2424 C CD  . ARG B 1 78  ? 206.242 223.165 279.109 1.00 54.47  ? 335 ARG D CD  1 
ATOM   2425 N NE  . ARG B 1 78  ? 205.637 222.775 280.377 1.00 57.92  ? 335 ARG D NE  1 
ATOM   2426 C CZ  . ARG B 1 78  ? 205.594 221.532 280.836 1.00 58.41  ? 335 ARG D CZ  1 
ATOM   2427 N NH1 . ARG B 1 78  ? 206.113 220.525 280.154 1.00 57.14  ? 335 ARG D NH1 1 
ATOM   2428 N NH2 . ARG B 1 78  ? 205.017 221.294 282.010 1.00 57.10  ? 335 ARG D NH2 1 
ATOM   2429 N N   . ALA B 1 79  ? 201.728 221.819 276.954 1.00 55.10  ? 336 ALA D N   1 
ATOM   2430 C CA  . ALA B 1 79  ? 200.699 220.915 277.440 1.00 57.22  ? 336 ALA D CA  1 
ATOM   2431 C C   . ALA B 1 79  ? 201.190 220.155 278.670 1.00 62.15  ? 336 ALA D C   1 
ATOM   2432 O O   . ALA B 1 79  ? 202.365 220.203 279.043 1.00 62.77  ? 336 ALA D O   1 
ATOM   2433 C CB  . ALA B 1 79  ? 200.276 219.941 276.342 1.00 59.35  ? 336 ALA D CB  1 
ATOM   2434 N N   . LYS B 1 80  ? 200.259 219.443 279.307 1.00 66.02  ? 337 LYS D N   1 
ATOM   2435 C CA  . LYS B 1 80  ? 200.563 218.791 280.577 1.00 64.91  ? 337 LYS D CA  1 
ATOM   2436 C C   . LYS B 1 80  ? 201.613 217.698 280.415 1.00 65.83  ? 337 LYS D C   1 
ATOM   2437 O O   . LYS B 1 80  ? 202.556 217.615 281.210 1.00 70.84  ? 337 LYS D O   1 
ATOM   2438 C CB  . LYS B 1 80  ? 199.285 218.219 281.188 1.00 68.97  ? 337 LYS D CB  1 
ATOM   2439 C CG  . LYS B 1 80  ? 199.486 217.589 282.554 1.00 75.08  ? 337 LYS D CG  1 
ATOM   2440 C CD  . LYS B 1 80  ? 199.993 218.608 283.560 1.00 73.83  ? 337 LYS D CD  1 
ATOM   2441 C CE  . LYS B 1 80  ? 201.187 218.073 284.333 1.00 72.55  ? 337 LYS D CE  1 
ATOM   2442 N NZ  . LYS B 1 80  ? 202.422 218.052 283.502 1.00 74.31  ? 337 LYS D NZ  1 
ATOM   2443 N N   . GLU B 1 81  ? 201.473 216.857 279.397 1.00 63.39  ? 338 GLU D N   1 
ATOM   2444 C CA  . GLU B 1 81  ? 202.372 215.730 279.209 1.00 69.22  ? 338 GLU D CA  1 
ATOM   2445 C C   . GLU B 1 81  ? 202.802 215.658 277.753 1.00 69.00  ? 338 GLU D C   1 
ATOM   2446 O O   . GLU B 1 81  ? 202.044 216.050 276.858 1.00 65.21  ? 338 GLU D O   1 
ATOM   2447 C CB  . GLU B 1 81  ? 201.710 214.402 279.614 1.00 75.53  ? 338 GLU D CB  1 
ATOM   2448 C CG  . GLU B 1 81  ? 200.612 213.839 278.680 1.00 76.90  ? 338 GLU D CG  1 
ATOM   2449 C CD  . GLU B 1 81  ? 199.463 214.794 278.328 1.00 78.76  ? 338 GLU D CD  1 
ATOM   2450 O OE1 . GLU B 1 81  ? 199.544 216.018 278.559 1.00 76.97  ? 338 GLU D OE1 1 
ATOM   2451 O OE2 . GLU B 1 81  ? 198.447 214.293 277.802 1.00 77.51  ? 338 GLU D OE2 1 
ATOM   2452 N N   . PRO B 1 82  ? 204.014 215.171 277.487 1.00 72.95  ? 339 PRO D N   1 
ATOM   2453 C CA  . PRO B 1 82  ? 204.460 215.031 276.097 1.00 70.59  ? 339 PRO D CA  1 
ATOM   2454 C C   . PRO B 1 82  ? 203.558 214.087 275.319 1.00 68.68  ? 339 PRO D C   1 
ATOM   2455 O O   . PRO B 1 82  ? 203.077 213.081 275.844 1.00 76.24  ? 339 PRO D O   1 
ATOM   2456 C CB  . PRO B 1 82  ? 205.879 214.468 276.234 1.00 68.77  ? 339 PRO D CB  1 
ATOM   2457 C CG  . PRO B 1 82  ? 206.316 214.864 277.597 1.00 70.58  ? 339 PRO D CG  1 
ATOM   2458 C CD  . PRO B 1 82  ? 205.081 214.841 278.446 1.00 72.16  ? 339 PRO D CD  1 
ATOM   2459 N N   . GLN B 1 83  ? 203.331 214.423 274.055 1.00 71.30  ? 340 GLN D N   1 
ATOM   2460 C CA  . GLN B 1 83  ? 202.532 213.593 273.173 1.00 75.58  ? 340 GLN D CA  1 
ATOM   2461 C C   . GLN B 1 83  ? 203.442 212.684 272.350 1.00 77.20  ? 340 GLN D C   1 
ATOM   2462 O O   . GLN B 1 83  ? 204.661 212.863 272.295 1.00 81.64  ? 340 GLN D O   1 
ATOM   2463 C CB  . GLN B 1 83  ? 201.658 214.463 272.272 1.00 72.70  ? 340 GLN D CB  1 
ATOM   2464 C CG  . GLN B 1 83  ? 200.755 215.421 273.025 1.00 71.74  ? 340 GLN D CG  1 
ATOM   2465 C CD  . GLN B 1 83  ? 200.378 216.633 272.199 1.00 74.65  ? 340 GLN D CD  1 
ATOM   2466 O OE1 . GLN B 1 83  ? 200.632 216.681 270.998 1.00 75.42  ? 340 GLN D OE1 1 
ATOM   2467 N NE2 . GLN B 1 83  ? 199.770 217.621 272.842 1.00 72.71  ? 340 GLN D NE2 1 
ATOM   2468 N N   . ASP B 1 84  ? 202.845 211.691 271.703 1.00 80.25  ? 341 ASP D N   1 
ATOM   2469 C CA  . ASP B 1 84  ? 203.560 210.788 270.806 1.00 81.21  ? 341 ASP D CA  1 
ATOM   2470 C C   . ASP B 1 84  ? 202.942 210.942 269.420 1.00 82.89  ? 341 ASP D C   1 
ATOM   2471 O O   . ASP B 1 84  ? 202.049 210.189 269.031 1.00 85.45  ? 341 ASP D O   1 
ATOM   2472 C CB  . ASP B 1 84  ? 203.489 209.348 271.297 1.00 89.86  ? 341 ASP D CB  1 
ATOM   2473 C CG  . ASP B 1 84  ? 204.612 208.494 270.749 1.00 92.79  ? 341 ASP D CG  1 
ATOM   2474 O OD1 . ASP B 1 84  ? 205.381 209.001 269.906 1.00 88.05  ? 341 ASP D OD1 1 
ATOM   2475 O OD2 . ASP B 1 84  ? 204.727 207.320 271.160 1.00 90.78  ? 341 ASP D OD2 1 
ATOM   2476 N N   . LEU B 1 85  ? 203.431 211.929 268.676 1.00 67.75  ? 342 LEU D N   1 
ATOM   2477 C CA  . LEU B 1 85  ? 202.976 212.220 267.331 1.00 66.67  ? 342 LEU D CA  1 
ATOM   2478 C C   . LEU B 1 85  ? 204.071 211.858 266.337 1.00 67.24  ? 342 LEU D C   1 
ATOM   2479 O O   . LEU B 1 85  ? 205.246 211.795 266.711 1.00 67.53  ? 342 LEU D O   1 
ATOM   2480 C CB  . LEU B 1 85  ? 202.604 213.702 267.189 1.00 64.94  ? 342 LEU D CB  1 
ATOM   2481 C CG  . LEU B 1 85  ? 201.637 214.233 268.248 1.00 65.53  ? 342 LEU D CG  1 
ATOM   2482 C CD1 . LEU B 1 85  ? 201.230 215.659 267.937 1.00 67.12  ? 342 LEU D CD1 1 
ATOM   2483 C CD2 . LEU B 1 85  ? 200.414 213.340 268.355 1.00 69.12  ? 342 LEU D CD2 1 
ATOM   2484 N N   . PRO B 1 86  ? 203.723 211.588 265.078 1.00 70.48  ? 343 PRO D N   1 
ATOM   2485 C CA  . PRO B 1 86  ? 204.752 211.187 264.112 1.00 72.26  ? 343 PRO D CA  1 
ATOM   2486 C C   . PRO B 1 86  ? 205.824 212.255 263.978 1.00 63.63  ? 343 PRO D C   1 
ATOM   2487 O O   . PRO B 1 86  ? 205.532 213.451 263.916 1.00 62.95  ? 343 PRO D O   1 
ATOM   2488 C CB  . PRO B 1 86  ? 203.968 211.004 262.807 1.00 75.71  ? 343 PRO D CB  1 
ATOM   2489 C CG  . PRO B 1 86  ? 202.543 210.847 263.226 1.00 75.70  ? 343 PRO D CG  1 
ATOM   2490 C CD  . PRO B 1 86  ? 202.389 211.667 264.461 1.00 69.44  ? 343 PRO D CD  1 
ATOM   2491 N N   . ASP B 1 87  ? 207.074 211.813 263.935 1.00 56.25  ? 344 ASP D N   1 
ATOM   2492 C CA  . ASP B 1 87  ? 208.207 212.721 263.873 1.00 58.64  ? 344 ASP D CA  1 
ATOM   2493 C C   . ASP B 1 87  ? 208.871 212.673 262.503 1.00 59.64  ? 344 ASP D C   1 
ATOM   2494 O O   . ASP B 1 87  ? 208.693 211.731 261.727 1.00 61.36  ? 344 ASP D O   1 
ATOM   2495 C CB  . ASP B 1 87  ? 209.220 212.405 264.981 1.00 56.24  ? 344 ASP D CB  1 
ATOM   2496 C CG  . ASP B 1 87  ? 210.233 211.348 264.581 1.00 63.80  ? 344 ASP D CG  1 
ATOM   2497 O OD1 . ASP B 1 87  ? 209.877 210.400 263.851 1.00 68.25  ? 344 ASP D OD1 1 
ATOM   2498 O OD2 . ASP B 1 87  ? 211.402 211.472 264.997 1.00 67.91  ? 344 ASP D OD2 1 
ATOM   2499 N N   . ASN B 1 88  ? 209.636 213.720 262.214 1.00 54.45  ? 345 ASN D N   1 
ATOM   2500 C CA  . ASN B 1 88  ? 210.346 213.887 260.953 1.00 54.29  ? 345 ASN D CA  1 
ATOM   2501 C C   . ASN B 1 88  ? 211.326 215.043 261.112 1.00 59.24  ? 345 ASN D C   1 
ATOM   2502 O O   . ASN B 1 88  ? 211.266 215.755 262.123 1.00 64.92  ? 345 ASN D O   1 
ATOM   2503 C CB  . ASN B 1 88  ? 209.359 214.135 259.812 1.00 50.15  ? 345 ASN D CB  1 
ATOM   2504 C CG  . ASN B 1 88  ? 208.213 215.022 260.222 1.00 52.88  ? 345 ASN D CG  1 
ATOM   2505 O OD1 . ASN B 1 88  ? 207.309 214.601 260.941 1.00 49.71  ? 345 ASN D OD1 1 
ATOM   2506 N ND2 . ASN B 1 88  ? 208.243 216.261 259.766 1.00 54.93  ? 345 ASN D ND2 1 
ATOM   2507 N N   . PRO B 1 89  ? 212.249 215.265 260.160 1.00 47.44  ? 346 PRO D N   1 
ATOM   2508 C CA  . PRO B 1 89  ? 213.226 216.352 260.325 1.00 45.74  ? 346 PRO D CA  1 
ATOM   2509 C C   . PRO B 1 89  ? 212.615 217.734 260.514 1.00 48.17  ? 346 PRO D C   1 
ATOM   2510 O O   . PRO B 1 89  ? 213.328 218.679 260.864 1.00 42.52  ? 346 PRO D O   1 
ATOM   2511 C CB  . PRO B 1 89  ? 214.039 216.276 259.029 1.00 42.91  ? 346 PRO D CB  1 
ATOM   2512 C CG  . PRO B 1 89  ? 214.004 214.838 258.675 1.00 40.55  ? 346 PRO D CG  1 
ATOM   2513 C CD  . PRO B 1 89  ? 212.625 214.368 259.051 1.00 41.95  ? 346 PRO D CD  1 
ATOM   2514 N N   . GLU B 1 90  ? 211.310 217.875 260.280 1.00 57.70  ? 347 GLU D N   1 
ATOM   2515 C CA  . GLU B 1 90  ? 210.647 219.143 260.565 1.00 52.20  ? 347 GLU D CA  1 
ATOM   2516 C C   . GLU B 1 90  ? 210.389 219.322 262.055 1.00 50.22  ? 347 GLU D C   1 
ATOM   2517 O O   . GLU B 1 90  ? 210.487 220.438 262.575 1.00 54.45  ? 347 GLU D O   1 
ATOM   2518 C CB  . GLU B 1 90  ? 209.332 219.241 259.793 1.00 46.15  ? 347 GLU D CB  1 
ATOM   2519 C CG  . GLU B 1 90  ? 209.451 218.931 258.317 1.00 55.80  ? 347 GLU D CG  1 
ATOM   2520 C CD  . GLU B 1 90  ? 208.535 219.788 257.474 1.00 62.43  ? 347 GLU D CD  1 
ATOM   2521 O OE1 . GLU B 1 90  ? 207.442 220.143 257.962 1.00 61.44  ? 347 GLU D OE1 1 
ATOM   2522 O OE2 . GLU B 1 90  ? 208.907 220.108 256.327 1.00 64.83  ? 347 GLU D OE2 1 
ATOM   2523 N N   . ARG B 1 91  ? 210.074 218.240 262.758 1.00 43.41  ? 348 ARG D N   1 
ATOM   2524 C CA  . ARG B 1 91  ? 209.638 218.337 264.145 1.00 44.44  ? 348 ARG D CA  1 
ATOM   2525 C C   . ARG B 1 91  ? 210.834 218.496 265.072 1.00 40.53  ? 348 ARG D C   1 
ATOM   2526 O O   . ARG B 1 91  ? 211.735 217.651 265.085 1.00 45.08  ? 348 ARG D O   1 
ATOM   2527 C CB  . ARG B 1 91  ? 208.827 217.104 264.537 1.00 41.30  ? 348 ARG D CB  1 
ATOM   2528 C CG  . ARG B 1 91  ? 207.576 217.430 265.322 1.00 37.27  ? 348 ARG D CG  1 
ATOM   2529 C CD  . ARG B 1 91  ? 206.541 216.327 265.240 1.00 41.57  ? 348 ARG D CD  1 
ATOM   2530 N NE  . ARG B 1 91  ? 205.350 216.668 266.006 1.00 41.79  ? 348 ARG D NE  1 
ATOM   2531 C CZ  . ARG B 1 91  ? 204.302 217.310 265.509 1.00 42.95  ? 348 ARG D CZ  1 
ATOM   2532 N NH1 . ARG B 1 91  ? 204.245 217.652 264.235 1.00 44.32  ? 348 ARG D NH1 1 
ATOM   2533 N NH2 . ARG B 1 91  ? 203.286 217.614 266.311 1.00 39.11  ? 348 ARG D NH2 1 
ATOM   2534 N N   . PHE B 1 92  ? 210.845 219.584 265.838 1.00 36.56  ? 349 PHE D N   1 
ATOM   2535 C CA  . PHE B 1 92  ? 211.712 219.662 267.001 1.00 42.25  ? 349 PHE D CA  1 
ATOM   2536 C C   . PHE B 1 92  ? 211.357 218.535 267.959 1.00 63.23  ? 349 PHE D C   1 
ATOM   2537 O O   . PHE B 1 92  ? 210.179 218.299 268.243 1.00 67.79  ? 349 PHE D O   1 
ATOM   2538 C CB  . PHE B 1 92  ? 211.547 221.011 267.699 1.00 39.17  ? 349 PHE D CB  1 
ATOM   2539 C CG  . PHE B 1 92  ? 212.442 222.089 267.170 1.00 48.69  ? 349 PHE D CG  1 
ATOM   2540 C CD1 . PHE B 1 92  ? 213.808 222.033 267.370 1.00 53.14  ? 349 PHE D CD1 1 
ATOM   2541 C CD2 . PHE B 1 92  ? 211.914 223.173 266.492 1.00 51.03  ? 349 PHE D CD2 1 
ATOM   2542 C CE1 . PHE B 1 92  ? 214.631 223.031 266.892 1.00 51.36  ? 349 PHE D CE1 1 
ATOM   2543 C CE2 . PHE B 1 92  ? 212.733 224.171 266.013 1.00 46.70  ? 349 PHE D CE2 1 
ATOM   2544 C CZ  . PHE B 1 92  ? 214.093 224.100 266.212 1.00 46.13  ? 349 PHE D CZ  1 
ATOM   2545 N N   . ASN B 1 93  ? 212.372 217.824 268.448 1.00 61.80  ? 350 ASN D N   1 
ATOM   2546 C CA  . ASN B 1 93  ? 212.137 216.738 269.387 1.00 40.05  ? 350 ASN D CA  1 
ATOM   2547 C C   . ASN B 1 93  ? 212.510 217.079 270.819 1.00 48.61  ? 350 ASN D C   1 
ATOM   2548 O O   . ASN B 1 93  ? 211.953 216.476 271.741 1.00 56.50  ? 350 ASN D O   1 
ATOM   2549 C CB  . ASN B 1 93  ? 212.904 215.479 268.960 1.00 36.93  ? 350 ASN D CB  1 
ATOM   2550 C CG  . ASN B 1 93  ? 214.400 215.687 268.942 1.00 47.74  ? 350 ASN D CG  1 
ATOM   2551 O OD1 . ASN B 1 93  ? 214.882 216.818 268.994 1.00 51.12  ? 350 ASN D OD1 1 
ATOM   2552 N ND2 . ASN B 1 93  ? 215.147 214.593 268.868 1.00 55.48  ? 350 ASN D ND2 1 
ATOM   2553 N N   . TRP B 1 94  ? 213.427 218.022 271.032 1.00 45.65  ? 351 TRP D N   1 
ATOM   2554 C CA  . TRP B 1 94  ? 213.843 218.388 272.381 1.00 40.21  ? 351 TRP D CA  1 
ATOM   2555 C C   . TRP B 1 94  ? 213.460 219.817 272.738 1.00 38.30  ? 351 TRP D C   1 
ATOM   2556 O O   . TRP B 1 94  ? 212.778 220.027 273.746 1.00 43.42  ? 351 TRP D O   1 
ATOM   2557 C CB  . TRP B 1 94  ? 215.352 218.182 272.543 1.00 41.33  ? 351 TRP D CB  1 
ATOM   2558 C CG  . TRP B 1 94  ? 215.753 218.077 273.967 1.00 50.30  ? 351 TRP D CG  1 
ATOM   2559 C CD1 . TRP B 1 94  ? 215.917 216.935 274.688 1.00 52.90  ? 351 TRP D CD1 1 
ATOM   2560 C CD2 . TRP B 1 94  ? 216.033 219.159 274.858 1.00 45.16  ? 351 TRP D CD2 1 
ATOM   2561 N NE1 . TRP B 1 94  ? 216.284 217.237 275.975 1.00 47.24  ? 351 TRP D NE1 1 
ATOM   2562 C CE2 . TRP B 1 94  ? 216.365 218.598 276.103 1.00 46.94  ? 351 TRP D CE2 1 
ATOM   2563 C CE3 . TRP B 1 94  ? 216.040 220.548 274.723 1.00 43.66  ? 351 TRP D CE3 1 
ATOM   2564 C CZ2 . TRP B 1 94  ? 216.696 219.378 277.206 1.00 48.05  ? 351 TRP D CZ2 1 
ATOM   2565 C CZ3 . TRP B 1 94  ? 216.371 221.317 275.815 1.00 47.30  ? 351 TRP D CZ3 1 
ATOM   2566 C CH2 . TRP B 1 94  ? 216.693 220.733 277.041 1.00 51.24  ? 351 TRP D CH2 1 
ATOM   2567 N N   . HIS B 1 95  ? 213.879 220.805 271.953 1.00 47.24  ? 352 HIS D N   1 
ATOM   2568 C CA  . HIS B 1 95  ? 213.557 222.189 272.271 1.00 47.00  ? 352 HIS D CA  1 
ATOM   2569 C C   . HIS B 1 95  ? 212.057 222.417 272.162 1.00 47.83  ? 352 HIS D C   1 
ATOM   2570 O O   . HIS B 1 95  ? 211.403 221.935 271.234 1.00 57.23  ? 352 HIS D O   1 
ATOM   2571 C CB  . HIS B 1 95  ? 214.304 223.140 271.337 1.00 49.05  ? 352 HIS D CB  1 
ATOM   2572 C CG  . HIS B 1 95  ? 215.675 223.507 271.813 1.00 49.45  ? 352 HIS D CG  1 
ATOM   2573 N ND1 . HIS B 1 95  ? 215.907 224.078 273.046 1.00 49.46  ? 352 HIS D ND1 1 
ATOM   2574 C CD2 . HIS B 1 95  ? 216.885 223.398 271.216 1.00 45.56  ? 352 HIS D CD2 1 
ATOM   2575 C CE1 . HIS B 1 95  ? 217.201 224.297 273.190 1.00 48.05  ? 352 HIS D CE1 1 
ATOM   2576 N NE2 . HIS B 1 95  ? 217.817 223.895 272.093 1.00 48.72  ? 352 HIS D NE2 1 
ATOM   2577 N N   . TYR B 1 96  ? 211.511 223.165 273.117 1.00 41.98  ? 353 TYR D N   1 
ATOM   2578 C CA  . TYR B 1 96  ? 210.073 223.388 273.178 1.00 42.76  ? 353 TYR D CA  1 
ATOM   2579 C C   . TYR B 1 96  ? 209.684 224.481 272.194 1.00 50.15  ? 353 TYR D C   1 
ATOM   2580 O O   . TYR B 1 96  ? 209.030 225.459 272.570 1.00 58.73  ? 353 TYR D O   1 
ATOM   2581 C CB  . TYR B 1 96  ? 209.645 223.768 274.599 1.00 39.91  ? 353 TYR D CB  1 
ATOM   2582 C CG  . TYR B 1 96  ? 209.741 222.652 275.621 1.00 46.84  ? 353 TYR D CG  1 
ATOM   2583 C CD1 . TYR B 1 96  ? 210.842 221.808 275.666 1.00 52.67  ? 353 TYR D CD1 1 
ATOM   2584 C CD2 . TYR B 1 96  ? 208.734 222.451 276.551 1.00 47.90  ? 353 TYR D CD2 1 
ATOM   2585 C CE1 . TYR B 1 96  ? 210.932 220.797 276.596 1.00 45.09  ? 353 TYR D CE1 1 
ATOM   2586 C CE2 . TYR B 1 96  ? 208.816 221.439 277.484 1.00 47.00  ? 353 TYR D CE2 1 
ATOM   2587 C CZ  . TYR B 1 96  ? 209.918 220.617 277.502 1.00 43.87  ? 353 TYR D CZ  1 
ATOM   2588 O OH  . TYR B 1 96  ? 210.009 219.608 278.429 1.00 53.86  ? 353 TYR D OH  1 
ATOM   2589 N N   . CYS B 1 97  ? 210.066 224.317 270.932 1.00 51.28  ? 354 CYS D N   1 
ATOM   2590 C CA  . CYS B 1 97  ? 210.037 225.393 269.958 1.00 50.42  ? 354 CYS D CA  1 
ATOM   2591 C C   . CYS B 1 97  ? 208.999 225.139 268.875 1.00 46.78  ? 354 CYS D C   1 
ATOM   2592 O O   . CYS B 1 97  ? 208.739 223.998 268.485 1.00 56.02  ? 354 CYS D O   1 
ATOM   2593 C CB  . CYS B 1 97  ? 211.410 225.577 269.311 1.00 49.32  ? 354 CYS D CB  1 
ATOM   2594 S SG  . CYS B 1 97  ? 212.658 226.210 270.435 1.00 62.14  ? 354 CYS D SG  1 
ATOM   2595 N N   . VAL B 1 98  ? 208.413 226.231 268.395 1.00 39.76  ? 355 VAL D N   1 
ATOM   2596 C CA  . VAL B 1 98  ? 207.469 226.206 267.289 1.00 40.59  ? 355 VAL D CA  1 
ATOM   2597 C C   . VAL B 1 98  ? 207.868 227.296 266.304 1.00 49.13  ? 355 VAL D C   1 
ATOM   2598 O O   . VAL B 1 98  ? 208.336 228.372 266.692 1.00 57.07  ? 355 VAL D O   1 
ATOM   2599 C CB  . VAL B 1 98  ? 206.008 226.378 267.771 1.00 51.61  ? 355 VAL D CB  1 
ATOM   2600 C CG1 . VAL B 1 98  ? 205.811 227.729 268.435 1.00 61.46  ? 355 VAL D CG1 1 
ATOM   2601 C CG2 . VAL B 1 98  ? 205.034 226.191 266.622 1.00 51.13  ? 355 VAL D CG2 1 
ATOM   2602 N N   . LEU B 1 99  ? 207.708 226.998 265.018 1.00 44.71  ? 356 LEU D N   1 
ATOM   2603 C CA  . LEU B 1 99  ? 208.067 227.912 263.947 1.00 44.41  ? 356 LEU D CA  1 
ATOM   2604 C C   . LEU B 1 99  ? 206.826 228.330 263.172 1.00 48.64  ? 356 LEU D C   1 
ATOM   2605 O O   . LEU B 1 99  ? 205.829 227.605 263.125 1.00 51.15  ? 356 LEU D O   1 
ATOM   2606 C CB  . LEU B 1 99  ? 209.070 227.274 262.983 1.00 36.51  ? 356 LEU D CB  1 
ATOM   2607 C CG  . LEU B 1 99  ? 210.376 226.752 263.575 1.00 39.99  ? 356 LEU D CG  1 
ATOM   2608 C CD1 . LEU B 1 99  ? 210.755 225.440 262.928 1.00 50.90  ? 356 LEU D CD1 1 
ATOM   2609 C CD2 . LEU B 1 99  ? 211.477 227.765 263.388 1.00 37.79  ? 356 LEU D CD2 1 
ATOM   2610 N N   . GLY B 1 100 ? 206.892 229.512 262.573 1.00 51.91  ? 357 GLY D N   1 
ATOM   2611 C CA  . GLY B 1 100 ? 205.885 229.911 261.617 1.00 48.49  ? 357 GLY D CA  1 
ATOM   2612 C C   . GLY B 1 100 ? 206.035 229.143 260.320 1.00 48.73  ? 357 GLY D C   1 
ATOM   2613 O O   . GLY B 1 100 ? 207.009 228.427 260.092 1.00 53.30  ? 357 GLY D O   1 
ATOM   2614 N N   . CYS B 1 101 ? 205.031 229.273 259.454 1.00 51.82  ? 358 CYS D N   1 
ATOM   2615 C CA  . CYS B 1 101 ? 205.083 228.550 258.188 1.00 61.74  ? 358 CYS D CA  1 
ATOM   2616 C C   . CYS B 1 101 ? 206.035 229.205 257.195 1.00 61.24  ? 358 CYS D C   1 
ATOM   2617 O O   . CYS B 1 101 ? 206.753 228.507 256.470 1.00 66.05  ? 358 CYS D O   1 
ATOM   2618 C CB  . CYS B 1 101 ? 203.686 228.439 257.581 1.00 63.01  ? 358 CYS D CB  1 
ATOM   2619 S SG  . CYS B 1 101 ? 202.765 226.964 258.065 1.00 67.34  ? 358 CYS D SG  1 
ATOM   2620 N N   . GLU B 1 102 ? 206.059 230.532 257.145 1.00 52.48  ? 359 GLU D N   1 
ATOM   2621 C CA  . GLU B 1 102 ? 206.725 231.243 256.066 1.00 49.34  ? 359 GLU D CA  1 
ATOM   2622 C C   . GLU B 1 102 ? 208.184 231.528 256.395 1.00 52.32  ? 359 GLU D C   1 
ATOM   2623 O O   . GLU B 1 102 ? 208.568 231.664 257.559 1.00 55.12  ? 359 GLU D O   1 
ATOM   2624 C CB  . GLU B 1 102 ? 206.001 232.554 255.764 1.00 53.34  ? 359 GLU D CB  1 
ATOM   2625 C CG  . GLU B 1 102 ? 204.522 232.379 255.483 1.00 58.04  ? 359 GLU D CG  1 
ATOM   2626 C CD  . GLU B 1 102 ? 204.250 231.286 254.470 1.00 61.62  ? 359 GLU D CD  1 
ATOM   2627 O OE1 . GLU B 1 102 ? 204.898 231.287 253.403 1.00 60.49  ? 359 GLU D OE1 1 
ATOM   2628 O OE2 . GLU B 1 102 ? 203.390 230.423 254.743 1.00 64.96  ? 359 GLU D OE2 1 
ATOM   2629 N N   . SER B 1 103 ? 208.994 231.619 255.345 1.00 51.24  ? 360 SER D N   1 
ATOM   2630 C CA  . SER B 1 103 ? 210.400 231.971 255.454 1.00 53.50  ? 360 SER D CA  1 
ATOM   2631 C C   . SER B 1 103 ? 210.636 233.318 254.787 1.00 54.06  ? 360 SER D C   1 
ATOM   2632 O O   . SER B 1 103 ? 209.928 233.698 253.850 1.00 61.11  ? 360 SER D O   1 
ATOM   2633 C CB  . SER B 1 103 ? 211.294 230.908 254.812 1.00 51.14  ? 360 SER D CB  1 
ATOM   2634 O OG  . SER B 1 103 ? 210.772 230.492 253.564 1.00 51.15  ? 360 SER D OG  1 
ATOM   2635 N N   . PHE B 1 104 ? 211.634 234.041 255.280 1.00 53.94  ? 361 PHE D N   1 
ATOM   2636 C CA  . PHE B 1 104 ? 211.974 235.362 254.772 1.00 56.72  ? 361 PHE D CA  1 
ATOM   2637 C C   . PHE B 1 104 ? 213.388 235.339 254.211 1.00 57.82  ? 361 PHE D C   1 
ATOM   2638 O O   . PHE B 1 104 ? 214.314 234.852 254.868 1.00 62.29  ? 361 PHE D O   1 
ATOM   2639 C CB  . PHE B 1 104 ? 211.848 236.415 255.873 1.00 56.36  ? 361 PHE D CB  1 
ATOM   2640 C CG  . PHE B 1 104 ? 210.473 236.506 256.471 1.00 52.78  ? 361 PHE D CG  1 
ATOM   2641 C CD1 . PHE B 1 104 ? 209.348 236.473 255.665 1.00 54.50  ? 361 PHE D CD1 1 
ATOM   2642 C CD2 . PHE B 1 104 ? 210.304 236.634 257.837 1.00 56.03  ? 361 PHE D CD2 1 
ATOM   2643 C CE1 . PHE B 1 104 ? 208.082 236.563 256.211 1.00 51.92  ? 361 PHE D CE1 1 
ATOM   2644 C CE2 . PHE B 1 104 ? 209.040 236.725 258.387 1.00 59.17  ? 361 PHE D CE2 1 
ATOM   2645 C CZ  . PHE B 1 104 ? 207.928 236.690 257.573 1.00 49.60  ? 361 PHE D CZ  1 
ATOM   2646 N N   . ILE B 1 105 ? 213.550 235.860 252.996 1.00 52.54  ? 362 ILE D N   1 
ATOM   2647 C CA  . ILE B 1 105 ? 214.857 235.890 252.344 1.00 53.99  ? 362 ILE D CA  1 
ATOM   2648 C C   . ILE B 1 105 ? 215.260 237.279 251.873 1.00 64.45  ? 362 ILE D C   1 
ATOM   2649 O O   . ILE B 1 105 ? 216.467 237.558 251.741 1.00 66.88  ? 362 ILE D O   1 
ATOM   2650 C CB  . ILE B 1 105 ? 214.885 234.891 251.163 1.00 58.19  ? 362 ILE D CB  1 
ATOM   2651 C CG1 . ILE B 1 105 ? 216.276 234.816 250.525 1.00 55.63  ? 362 ILE D CG1 1 
ATOM   2652 C CG2 . ILE B 1 105 ? 213.835 235.258 250.127 1.00 61.42  ? 362 ILE D CG2 1 
ATOM   2653 C CD1 . ILE B 1 105 ? 217.346 234.280 251.440 1.00 50.77  ? 362 ILE D CD1 1 
ATOM   2654 N N   . SER B 1 106 ? 214.327 238.197 251.633 1.00 68.68  ? 363 SER D N   1 
ATOM   2655 C CA  . SER B 1 106 ? 214.665 239.537 251.180 1.00 61.57  ? 363 SER D CA  1 
ATOM   2656 C C   . SER B 1 106 ? 213.684 240.522 251.799 1.00 64.68  ? 363 SER D C   1 
ATOM   2657 O O   . SER B 1 106 ? 212.729 240.136 252.478 1.00 66.50  ? 363 SER D O   1 
ATOM   2658 C CB  . SER B 1 106 ? 214.649 239.622 249.651 1.00 65.87  ? 363 SER D CB  1 
ATOM   2659 O OG  . SER B 1 106 ? 213.439 239.103 249.129 1.00 67.03  ? 363 SER D OG  1 
ATOM   2660 N N   . GLY B 1 107 ? 213.929 241.808 251.557 1.00 71.35  ? 364 GLY D N   1 
ATOM   2661 C CA  . GLY B 1 107 ? 213.037 242.831 252.062 1.00 69.21  ? 364 GLY D CA  1 
ATOM   2662 C C   . GLY B 1 107 ? 213.146 242.991 253.568 1.00 67.84  ? 364 GLY D C   1 
ATOM   2663 O O   . GLY B 1 107 ? 214.128 242.592 254.199 1.00 64.47  ? 364 GLY D O   1 
ATOM   2664 N N   . ARG B 1 108 ? 212.109 243.584 254.154 1.00 61.59  ? 365 ARG D N   1 
ATOM   2665 C CA  . ARG B 1 108 ? 212.082 243.826 255.591 1.00 60.52  ? 365 ARG D CA  1 
ATOM   2666 C C   . ARG B 1 108 ? 210.659 243.658 256.097 1.00 60.96  ? 365 ARG D C   1 
ATOM   2667 O O   . ARG B 1 108 ? 209.723 244.220 255.520 1.00 52.58  ? 365 ARG D O   1 
ATOM   2668 C CB  . ARG B 1 108 ? 212.621 245.217 255.920 1.00 59.83  ? 365 ARG D CB  1 
ATOM   2669 C CG  . ARG B 1 108 ? 212.206 246.303 254.947 1.00 63.06  ? 365 ARG D CG  1 
ATOM   2670 C CD  . ARG B 1 108 ? 212.821 247.640 255.325 1.00 61.51  ? 365 ARG D CD  1 
ATOM   2671 N NE  . ARG B 1 108 ? 212.437 248.699 254.400 1.00 57.12  ? 365 ARG D NE  1 
ATOM   2672 C CZ  . ARG B 1 108 ? 213.199 249.135 253.408 1.00 59.91  ? 365 ARG D CZ  1 
ATOM   2673 N NH1 . ARG B 1 108 ? 214.403 248.633 253.190 1.00 58.09  ? 365 ARG D NH1 1 
ATOM   2674 N NH2 . ARG B 1 108 ? 212.743 250.100 252.615 1.00 60.64  ? 365 ARG D NH2 1 
ATOM   2675 N N   . HIS B 1 109 ? 210.508 242.902 257.183 1.00 66.94  ? 366 HIS D N   1 
ATOM   2676 C CA  . HIS B 1 109 ? 209.209 242.506 257.708 1.00 60.59  ? 366 HIS D CA  1 
ATOM   2677 C C   . HIS B 1 109 ? 209.192 242.683 259.221 1.00 57.60  ? 366 HIS D C   1 
ATOM   2678 O O   . HIS B 1 109 ? 210.215 242.982 259.840 1.00 59.14  ? 366 HIS D O   1 
ATOM   2679 C CB  . HIS B 1 109 ? 208.889 241.049 257.344 1.00 53.59  ? 366 HIS D CB  1 
ATOM   2680 C CG  . HIS B 1 109 ? 209.390 240.642 255.992 1.00 63.31  ? 366 HIS D CG  1 
ATOM   2681 N ND1 . HIS B 1 109 ? 208.566 240.532 254.893 1.00 65.82  ? 366 HIS D ND1 1 
ATOM   2682 C CD2 . HIS B 1 109 ? 210.632 240.312 255.564 1.00 59.29  ? 366 HIS D CD2 1 
ATOM   2683 C CE1 . HIS B 1 109 ? 209.280 240.159 253.845 1.00 55.70  ? 366 HIS D CE1 1 
ATOM   2684 N NE2 . HIS B 1 109 ? 210.536 240.019 254.226 1.00 54.62  ? 366 HIS D NE2 1 
ATOM   2685 N N   . TYR B 1 110 ? 208.014 242.506 259.819 1.00 59.27  ? 367 TYR D N   1 
ATOM   2686 C CA  . TYR B 1 110 ? 207.906 242.595 261.269 1.00 59.92  ? 367 TYR D CA  1 
ATOM   2687 C C   . TYR B 1 110 ? 206.676 241.838 261.747 1.00 69.11  ? 367 TYR D C   1 
ATOM   2688 O O   . TYR B 1 110 ? 205.756 241.554 260.976 1.00 74.47  ? 367 TYR D O   1 
ATOM   2689 C CB  . TYR B 1 110 ? 207.843 244.049 261.747 1.00 57.68  ? 367 TYR D CB  1 
ATOM   2690 C CG  . TYR B 1 110 ? 206.450 244.592 261.990 1.00 63.02  ? 367 TYR D CG  1 
ATOM   2691 C CD1 . TYR B 1 110 ? 205.548 244.758 260.951 1.00 66.80  ? 367 TYR D CD1 1 
ATOM   2692 C CD2 . TYR B 1 110 ? 206.039 244.937 263.269 1.00 65.66  ? 367 TYR D CD2 1 
ATOM   2693 C CE1 . TYR B 1 110 ? 204.280 245.255 261.183 1.00 62.89  ? 367 TYR D CE1 1 
ATOM   2694 C CE2 . TYR B 1 110 ? 204.774 245.432 263.506 1.00 66.62  ? 367 TYR D CE2 1 
ATOM   2695 C CZ  . TYR B 1 110 ? 203.899 245.587 262.459 1.00 61.48  ? 367 TYR D CZ  1 
ATOM   2696 O OH  . TYR B 1 110 ? 202.637 246.079 262.687 1.00 62.04  ? 367 TYR D OH  1 
ATOM   2697 N N   . TRP B 1 111 ? 206.673 241.516 263.039 1.00 54.95  ? 368 TRP D N   1 
ATOM   2698 C CA  . TRP B 1 111 ? 205.514 240.873 263.647 1.00 51.81  ? 368 TRP D CA  1 
ATOM   2699 C C   . TRP B 1 111 ? 205.491 241.151 265.145 1.00 49.68  ? 368 TRP D C   1 
ATOM   2700 O O   . TRP B 1 111 ? 206.537 241.316 265.778 1.00 48.02  ? 368 TRP D O   1 
ATOM   2701 C CB  . TRP B 1 111 ? 205.495 239.364 263.375 1.00 42.03  ? 368 TRP D CB  1 
ATOM   2702 C CG  . TRP B 1 111 ? 206.710 238.631 263.836 1.00 43.53  ? 368 TRP D CG  1 
ATOM   2703 C CD1 . TRP B 1 111 ? 206.879 238.004 265.032 1.00 53.25  ? 368 TRP D CD1 1 
ATOM   2704 C CD2 . TRP B 1 111 ? 207.922 238.430 263.101 1.00 46.05  ? 368 TRP D CD2 1 
ATOM   2705 N NE1 . TRP B 1 111 ? 208.126 237.432 265.094 1.00 60.83  ? 368 TRP D NE1 1 
ATOM   2706 C CE2 . TRP B 1 111 ? 208.786 237.680 263.920 1.00 54.12  ? 368 TRP D CE2 1 
ATOM   2707 C CE3 . TRP B 1 111 ? 208.364 238.816 261.833 1.00 47.21  ? 368 TRP D CE3 1 
ATOM   2708 C CZ2 . TRP B 1 111 ? 210.064 237.308 263.513 1.00 49.15  ? 368 TRP D CZ2 1 
ATOM   2709 C CZ3 . TRP B 1 111 ? 209.633 238.445 261.431 1.00 47.99  ? 368 TRP D CZ3 1 
ATOM   2710 C CH2 . TRP B 1 111 ? 210.468 237.701 262.268 1.00 46.64  ? 368 TRP D CH2 1 
ATOM   2711 N N   . GLU B 1 112 ? 204.284 241.181 265.704 1.00 61.05  ? 369 GLU D N   1 
ATOM   2712 C CA  . GLU B 1 112 ? 204.061 241.532 267.100 1.00 56.08  ? 369 GLU D CA  1 
ATOM   2713 C C   . GLU B 1 112 ? 203.603 240.311 267.885 1.00 62.49  ? 369 GLU D C   1 
ATOM   2714 O O   . GLU B 1 112 ? 202.659 239.624 267.480 1.00 68.79  ? 369 GLU D O   1 
ATOM   2715 C CB  . GLU B 1 112 ? 203.021 242.646 267.221 1.00 56.11  ? 369 GLU D CB  1 
ATOM   2716 C CG  . GLU B 1 112 ? 203.610 244.041 267.242 1.00 62.28  ? 369 GLU D CG  1 
ATOM   2717 C CD  . GLU B 1 112 ? 202.548 245.115 267.190 1.00 69.64  ? 369 GLU D CD  1 
ATOM   2718 O OE1 . GLU B 1 112 ? 201.351 244.765 267.167 1.00 71.52  ? 369 GLU D OE1 1 
ATOM   2719 O OE2 . GLU B 1 112 ? 202.910 246.310 267.171 1.00 66.49  ? 369 GLU D OE2 1 
ATOM   2720 N N   . VAL B 1 113 ? 204.264 240.054 269.009 1.00 59.00  ? 370 VAL D N   1 
ATOM   2721 C CA  . VAL B 1 113 ? 203.950 238.941 269.893 1.00 55.91  ? 370 VAL D CA  1 
ATOM   2722 C C   . VAL B 1 113 ? 203.367 239.525 271.171 1.00 56.06  ? 370 VAL D C   1 
ATOM   2723 O O   . VAL B 1 113 ? 203.993 240.372 271.824 1.00 64.26  ? 370 VAL D O   1 
ATOM   2724 C CB  . VAL B 1 113 ? 205.185 238.083 270.193 1.00 57.25  ? 370 VAL D CB  1 
ATOM   2725 C CG1 . VAL B 1 113 ? 204.777 236.794 270.883 1.00 61.54  ? 370 VAL D CG1 1 
ATOM   2726 C CG2 . VAL B 1 113 ? 205.952 237.796 268.915 1.00 58.65  ? 370 VAL D CG2 1 
ATOM   2727 N N   . GLU B 1 114 ? 202.165 239.078 271.521 1.00 56.74  ? 371 GLU D N   1 
ATOM   2728 C CA  . GLU B 1 114 ? 201.502 239.489 272.754 1.00 60.72  ? 371 GLU D CA  1 
ATOM   2729 C C   . GLU B 1 114 ? 201.876 238.499 273.846 1.00 60.09  ? 371 GLU D C   1 
ATOM   2730 O O   . GLU B 1 114 ? 201.193 237.494 274.051 1.00 66.09  ? 371 GLU D O   1 
ATOM   2731 C CB  . GLU B 1 114 ? 199.993 239.552 272.558 1.00 63.13  ? 371 GLU D CB  1 
ATOM   2732 C CG  . GLU B 1 114 ? 199.522 240.731 271.735 1.00 65.47  ? 371 GLU D CG  1 
ATOM   2733 C CD  . GLU B 1 114 ? 198.311 241.406 272.340 1.00 67.86  ? 371 GLU D CD  1 
ATOM   2734 O OE1 . GLU B 1 114 ? 197.943 241.054 273.480 1.00 67.05  ? 371 GLU D OE1 1 
ATOM   2735 O OE2 . GLU B 1 114 ? 197.725 242.286 271.677 1.00 70.85  ? 371 GLU D OE2 1 
ATOM   2736 N N   . VAL B 1 115 ? 202.973 238.779 274.555 1.00 55.43  ? 372 VAL D N   1 
ATOM   2737 C CA  . VAL B 1 115 ? 203.432 237.889 275.615 1.00 58.49  ? 372 VAL D CA  1 
ATOM   2738 C C   . VAL B 1 115 ? 202.579 237.988 276.868 1.00 56.34  ? 372 VAL D C   1 
ATOM   2739 O O   . VAL B 1 115 ? 202.798 237.220 277.814 1.00 55.76  ? 372 VAL D O   1 
ATOM   2740 C CB  . VAL B 1 115 ? 204.904 238.169 275.973 1.00 53.82  ? 372 VAL D CB  1 
ATOM   2741 C CG1 . VAL B 1 115 ? 205.772 238.084 274.732 1.00 54.64  ? 372 VAL D CG1 1 
ATOM   2742 C CG2 . VAL B 1 115 ? 205.034 239.527 276.631 1.00 52.81  ? 372 VAL D CG2 1 
ATOM   2743 N N   . GLY B 1 116 ? 201.613 238.902 276.905 1.00 68.62  ? 373 GLY D N   1 
ATOM   2744 C CA  . GLY B 1 116 ? 200.727 239.031 278.043 1.00 74.53  ? 373 GLY D CA  1 
ATOM   2745 C C   . GLY B 1 116 ? 201.451 239.286 279.348 1.00 78.13  ? 373 GLY D C   1 
ATOM   2746 O O   . GLY B 1 116 ? 202.293 240.184 279.437 1.00 81.42  ? 373 GLY D O   1 
ATOM   2747 N N   . ASP B 1 117 ? 201.132 238.494 280.366 1.00 81.91  ? 374 ASP D N   1 
ATOM   2748 C CA  . ASP B 1 117 ? 201.750 238.594 281.681 1.00 81.45  ? 374 ASP D CA  1 
ATOM   2749 C C   . ASP B 1 117 ? 202.403 237.275 282.062 1.00 81.35  ? 374 ASP D C   1 
ATOM   2750 O O   . ASP B 1 117 ? 202.275 236.798 283.192 1.00 82.77  ? 374 ASP D O   1 
ATOM   2751 C CB  . ASP B 1 117 ? 200.727 239.014 282.733 1.00 81.61  ? 374 ASP D CB  1 
ATOM   2752 C CG  . ASP B 1 117 ? 199.435 238.231 282.629 1.00 84.16  ? 374 ASP D CG  1 
ATOM   2753 O OD1 . ASP B 1 117 ? 199.211 237.592 281.580 1.00 81.50  ? 374 ASP D OD1 1 
ATOM   2754 O OD2 . ASP B 1 117 ? 198.644 238.254 283.596 1.00 84.18  ? 374 ASP D OD2 1 
ATOM   2755 N N   . ARG B 1 118 ? 203.114 236.664 281.119 1.00 60.26  ? 375 ARG D N   1 
ATOM   2756 C CA  . ARG B 1 118 ? 203.733 235.373 281.363 1.00 56.53  ? 375 ARG D CA  1 
ATOM   2757 C C   . ARG B 1 118 ? 204.989 235.542 282.212 1.00 55.97  ? 375 ARG D C   1 
ATOM   2758 O O   . ARG B 1 118 ? 205.406 236.653 282.550 1.00 57.36  ? 375 ARG D O   1 
ATOM   2759 C CB  . ARG B 1 118 ? 204.063 234.685 280.044 1.00 56.66  ? 375 ARG D CB  1 
ATOM   2760 C CG  . ARG B 1 118 ? 202.872 234.048 279.375 1.00 55.07  ? 375 ARG D CG  1 
ATOM   2761 C CD  . ARG B 1 118 ? 203.311 233.161 278.238 1.00 53.70  ? 375 ARG D CD  1 
ATOM   2762 N NE  . ARG B 1 118 ? 204.082 232.018 278.708 1.00 50.86  ? 375 ARG D NE  1 
ATOM   2763 C CZ  . ARG B 1 118 ? 203.601 230.787 278.805 1.00 56.14  ? 375 ARG D CZ  1 
ATOM   2764 N NH1 . ARG B 1 118 ? 202.352 230.505 278.474 1.00 57.61  ? 375 ARG D NH1 1 
ATOM   2765 N NH2 . ARG B 1 118 ? 204.395 229.814 279.242 1.00 59.02  ? 375 ARG D NH2 1 
ATOM   2766 N N   . LYS B 1 119 ? 205.604 234.412 282.555 1.00 57.21  ? 376 LYS D N   1 
ATOM   2767 C CA  . LYS B 1 119 ? 206.796 234.403 283.385 1.00 61.31  ? 376 LYS D CA  1 
ATOM   2768 C C   . LYS B 1 119 ? 208.029 233.860 282.681 1.00 61.52  ? 376 LYS D C   1 
ATOM   2769 O O   . LYS B 1 119 ? 209.133 234.000 283.219 1.00 60.87  ? 376 LYS D O   1 
ATOM   2770 C CB  . LYS B 1 119 ? 206.549 233.583 284.662 1.00 61.56  ? 376 LYS D CB  1 
ATOM   2771 C CG  . LYS B 1 119 ? 205.566 234.214 285.639 1.00 61.46  ? 376 LYS D CG  1 
ATOM   2772 C CD  . LYS B 1 119 ? 205.661 235.732 285.641 1.00 69.45  ? 376 LYS D CD  1 
ATOM   2773 C CE  . LYS B 1 119 ? 206.696 236.224 286.638 1.00 67.31  ? 376 LYS D CE  1 
ATOM   2774 N NZ  . LYS B 1 119 ? 206.833 237.708 286.617 1.00 60.20  ? 376 LYS D NZ  1 
ATOM   2775 N N   . GLU B 1 120 ? 207.885 233.255 281.505 1.00 62.44  ? 377 GLU D N   1 
ATOM   2776 C CA  . GLU B 1 120 ? 209.035 232.709 280.788 1.00 58.57  ? 377 GLU D CA  1 
ATOM   2777 C C   . GLU B 1 120 ? 208.651 232.494 279.335 1.00 56.12  ? 377 GLU D C   1 
ATOM   2778 O O   . GLU B 1 120 ? 207.696 231.765 279.051 1.00 58.26  ? 377 GLU D O   1 
ATOM   2779 C CB  . GLU B 1 120 ? 209.499 231.401 281.422 1.00 53.76  ? 377 GLU D CB  1 
ATOM   2780 C CG  . GLU B 1 120 ? 210.837 230.907 280.916 1.00 62.51  ? 377 GLU D CG  1 
ATOM   2781 C CD  . GLU B 1 120 ? 210.698 229.930 279.768 1.00 71.42  ? 377 GLU D CD  1 
ATOM   2782 O OE1 . GLU B 1 120 ? 209.555 229.536 279.458 1.00 72.49  ? 377 GLU D OE1 1 
ATOM   2783 O OE2 . GLU B 1 120 ? 211.731 229.559 279.173 1.00 72.87  ? 377 GLU D OE2 1 
ATOM   2784 N N   . TRP B 1 121 ? 209.388 233.119 278.422 1.00 48.34  ? 378 TRP D N   1 
ATOM   2785 C CA  . TRP B 1 121 ? 209.178 232.917 276.995 1.00 45.26  ? 378 TRP D CA  1 
ATOM   2786 C C   . TRP B 1 121 ? 210.432 233.352 276.253 1.00 48.77  ? 378 TRP D C   1 
ATOM   2787 O O   . TRP B 1 121 ? 211.281 234.065 276.793 1.00 55.92  ? 378 TRP D O   1 
ATOM   2788 C CB  . TRP B 1 121 ? 207.952 233.682 276.489 1.00 48.21  ? 378 TRP D CB  1 
ATOM   2789 C CG  . TRP B 1 121 ? 207.808 235.054 277.060 1.00 46.91  ? 378 TRP D CG  1 
ATOM   2790 C CD1 . TRP B 1 121 ? 207.125 235.403 278.184 1.00 49.68  ? 378 TRP D CD1 1 
ATOM   2791 C CD2 . TRP B 1 121 ? 208.353 236.267 276.529 1.00 55.55  ? 378 TRP D CD2 1 
ATOM   2792 N NE1 . TRP B 1 121 ? 207.212 236.758 278.390 1.00 56.56  ? 378 TRP D NE1 1 
ATOM   2793 C CE2 . TRP B 1 121 ? 207.962 237.311 277.386 1.00 56.29  ? 378 TRP D CE2 1 
ATOM   2794 C CE3 . TRP B 1 121 ? 209.136 236.571 275.412 1.00 57.14  ? 378 TRP D CE3 1 
ATOM   2795 C CZ2 . TRP B 1 121 ? 208.329 238.634 277.165 1.00 52.18  ? 378 TRP D CZ2 1 
ATOM   2796 C CZ3 . TRP B 1 121 ? 209.497 237.887 275.194 1.00 46.16  ? 378 TRP D CZ3 1 
ATOM   2797 C CH2 . TRP B 1 121 ? 209.092 238.901 276.063 1.00 45.04  ? 378 TRP D CH2 1 
ATOM   2798 N N   . HIS B 1 122 ? 210.541 232.905 275.004 1.00 47.53  ? 379 HIS D N   1 
ATOM   2799 C CA  . HIS B 1 122 ? 211.630 233.329 274.137 1.00 48.30  ? 379 HIS D CA  1 
ATOM   2800 C C   . HIS B 1 122 ? 211.121 233.424 272.709 1.00 47.63  ? 379 HIS D C   1 
ATOM   2801 O O   . HIS B 1 122 ? 210.454 232.509 272.214 1.00 52.33  ? 379 HIS D O   1 
ATOM   2802 C CB  . HIS B 1 122 ? 212.816 232.369 274.208 1.00 48.89  ? 379 HIS D CB  1 
ATOM   2803 C CG  . HIS B 1 122 ? 213.788 232.697 275.292 1.00 49.97  ? 379 HIS D CG  1 
ATOM   2804 N ND1 . HIS B 1 122 ? 213.439 232.703 276.625 1.00 54.34  ? 379 HIS D ND1 1 
ATOM   2805 C CD2 . HIS B 1 122 ? 215.096 233.036 275.243 1.00 49.92  ? 379 HIS D CD2 1 
ATOM   2806 C CE1 . HIS B 1 122 ? 214.492 233.030 277.350 1.00 59.82  ? 379 HIS D CE1 1 
ATOM   2807 N NE2 . HIS B 1 122 ? 215.511 233.236 276.536 1.00 62.21  ? 379 HIS D NE2 1 
ATOM   2808 N N   . ILE B 1 123 ? 211.455 234.539 272.052 1.00 42.58  ? 380 ILE D N   1 
ATOM   2809 C CA  . ILE B 1 123 ? 211.030 234.801 270.685 1.00 49.05  ? 380 ILE D CA  1 
ATOM   2810 C C   . ILE B 1 123 ? 212.222 235.285 269.873 1.00 46.16  ? 380 ILE D C   1 
ATOM   2811 O O   . ILE B 1 123 ? 213.176 235.859 270.402 1.00 48.51  ? 380 ILE D O   1 
ATOM   2812 C CB  . ILE B 1 123 ? 209.891 235.841 270.615 1.00 48.20  ? 380 ILE D CB  1 
ATOM   2813 C CG1 . ILE B 1 123 ? 210.136 236.970 271.611 1.00 50.91  ? 380 ILE D CG1 1 
ATOM   2814 C CG2 . ILE B 1 123 ? 208.560 235.189 270.910 1.00 45.96  ? 380 ILE D CG2 1 
ATOM   2815 C CD1 . ILE B 1 123 ? 208.994 237.952 271.692 1.00 52.38  ? 380 ILE D CD1 1 
ATOM   2816 N N   . GLY B 1 124 ? 212.145 235.062 268.565 1.00 30.55  ? 381 GLY D N   1 
ATOM   2817 C CA  . GLY B 1 124 ? 213.200 235.502 267.673 1.00 29.49  ? 381 GLY D CA  1 
ATOM   2818 C C   . GLY B 1 124 ? 213.081 234.818 266.326 1.00 34.43  ? 381 GLY D C   1 
ATOM   2819 O O   . GLY B 1 124 ? 212.008 234.342 265.947 1.00 38.68  ? 381 GLY D O   1 
ATOM   2820 N N   . VAL B 1 125 ? 214.208 234.765 265.617 1.00 46.73  ? 382 VAL D N   1 
ATOM   2821 C CA  . VAL B 1 125 ? 214.280 234.117 264.315 1.00 46.19  ? 382 VAL D CA  1 
ATOM   2822 C C   . VAL B 1 125 ? 215.371 233.055 264.339 1.00 51.82  ? 382 VAL D C   1 
ATOM   2823 O O   . VAL B 1 125 ? 216.263 233.061 265.189 1.00 57.61  ? 382 VAL D O   1 
ATOM   2824 C CB  . VAL B 1 125 ? 214.540 235.116 263.169 1.00 46.21  ? 382 VAL D CB  1 
ATOM   2825 C CG1 . VAL B 1 125 ? 213.545 236.254 263.219 1.00 52.51  ? 382 VAL D CG1 1 
ATOM   2826 C CG2 . VAL B 1 125 ? 215.959 235.639 263.242 1.00 48.28  ? 382 VAL D CG2 1 
ATOM   2827 N N   . CYS B 1 126 ? 215.278 232.129 263.388 1.00 58.62  ? 383 CYS D N   1 
ATOM   2828 C CA  . CYS B 1 126 ? 216.223 231.029 263.281 1.00 60.06  ? 383 CYS D CA  1 
ATOM   2829 C C   . CYS B 1 126 ? 216.509 230.744 261.814 1.00 58.73  ? 383 CYS D C   1 
ATOM   2830 O O   . CYS B 1 126 ? 215.719 231.076 260.929 1.00 54.60  ? 383 CYS D O   1 
ATOM   2831 C CB  . CYS B 1 126 ? 215.703 229.764 263.972 1.00 63.76  ? 383 CYS D CB  1 
ATOM   2832 S SG  . CYS B 1 126 ? 214.799 228.649 262.883 1.00 91.00  ? 383 CYS D SG  1 
ATOM   2833 N N   . SER B 1 127 ? 217.657 230.122 261.566 1.00 60.36  ? 384 SER D N   1 
ATOM   2834 C CA  . SER B 1 127 ? 218.063 229.788 260.212 1.00 59.27  ? 384 SER D CA  1 
ATOM   2835 C C   . SER B 1 127 ? 217.243 228.615 259.678 1.00 60.84  ? 384 SER D C   1 
ATOM   2836 O O   . SER B 1 127 ? 216.619 227.859 260.426 1.00 65.79  ? 384 SER D O   1 
ATOM   2837 C CB  . SER B 1 127 ? 219.556 229.465 260.168 1.00 57.69  ? 384 SER D CB  1 
ATOM   2838 O OG  . SER B 1 127 ? 219.949 229.037 258.878 1.00 54.13  ? 384 SER D OG  1 
ATOM   2839 N N   . LYS B 1 128 ? 217.248 228.472 258.352 1.00 60.31  ? 385 LYS D N   1 
ATOM   2840 C CA  . LYS B 1 128 ? 216.486 227.403 257.715 1.00 56.12  ? 385 LYS D CA  1 
ATOM   2841 C C   . LYS B 1 128 ? 217.028 226.026 258.075 1.00 55.23  ? 385 LYS D C   1 
ATOM   2842 O O   . LYS B 1 128 ? 216.262 225.061 258.162 1.00 53.10  ? 385 LYS D O   1 
ATOM   2843 C CB  . LYS B 1 128 ? 216.496 227.597 256.199 1.00 59.48  ? 385 LYS D CB  1 
ATOM   2844 C CG  . LYS B 1 128 ? 215.580 226.661 255.430 1.00 62.90  ? 385 LYS D CG  1 
ATOM   2845 C CD  . LYS B 1 128 ? 214.229 226.528 256.103 1.00 61.83  ? 385 LYS D CD  1 
ATOM   2846 C CE  . LYS B 1 128 ? 213.271 225.712 255.253 1.00 66.63  ? 385 LYS D CE  1 
ATOM   2847 N NZ  . LYS B 1 128 ? 213.275 226.160 253.833 1.00 62.86  ? 385 LYS D NZ  1 
ATOM   2848 N N   . ASN B 1 129 ? 218.335 225.915 258.295 1.00 56.54  ? 386 ASN D N   1 
ATOM   2849 C CA  . ASN B 1 129 ? 219.001 224.630 258.497 1.00 58.56  ? 386 ASN D CA  1 
ATOM   2850 C C   . ASN B 1 129 ? 219.270 224.341 259.968 1.00 59.73  ? 386 ASN D C   1 
ATOM   2851 O O   . ASN B 1 129 ? 220.311 223.773 260.310 1.00 60.62  ? 386 ASN D O   1 
ATOM   2852 C CB  . ASN B 1 129 ? 220.301 224.591 257.702 1.00 58.27  ? 386 ASN D CB  1 
ATOM   2853 C CG  . ASN B 1 129 ? 220.143 225.150 256.307 1.00 56.35  ? 386 ASN D CG  1 
ATOM   2854 O OD1 . ASN B 1 129 ? 219.049 225.147 255.746 1.00 57.01  ? 386 ASN D OD1 1 
ATOM   2855 N ND2 . ASN B 1 129 ? 221.238 225.634 255.737 1.00 59.58  ? 386 ASN D ND2 1 
ATOM   2856 N N   . VAL B 1 130 ? 218.356 224.720 260.861 1.00 52.86  ? 387 VAL D N   1 
ATOM   2857 C CA  . VAL B 1 130 ? 218.599 224.549 262.287 1.00 49.67  ? 387 VAL D CA  1 
ATOM   2858 C C   . VAL B 1 130 ? 218.589 223.068 262.649 1.00 65.10  ? 387 VAL D C   1 
ATOM   2859 O O   . VAL B 1 130 ? 217.966 222.238 261.974 1.00 67.59  ? 387 VAL D O   1 
ATOM   2860 C CB  . VAL B 1 130 ? 217.558 225.327 263.111 1.00 49.31  ? 387 VAL D CB  1 
ATOM   2861 C CG1 . VAL B 1 130 ? 217.935 226.793 263.178 1.00 50.86  ? 387 VAL D CG1 1 
ATOM   2862 C CG2 . VAL B 1 130 ? 216.177 225.156 262.511 1.00 50.61  ? 387 VAL D CG2 1 
ATOM   2863 N N   . GLN B 1 131 ? 219.292 222.733 263.730 1.00 66.72  ? 388 GLN D N   1 
ATOM   2864 C CA  . GLN B 1 131 ? 219.400 221.356 264.210 1.00 53.90  ? 388 GLN D CA  1 
ATOM   2865 C C   . GLN B 1 131 ? 218.183 221.042 265.068 1.00 53.01  ? 388 GLN D C   1 
ATOM   2866 O O   . GLN B 1 131 ? 218.135 221.384 266.251 1.00 57.11  ? 388 GLN D O   1 
ATOM   2867 C CB  . GLN B 1 131 ? 220.692 221.164 264.993 1.00 44.21  ? 388 GLN D CB  1 
ATOM   2868 C CG  . GLN B 1 131 ? 220.896 219.760 265.514 1.00 50.60  ? 388 GLN D CG  1 
ATOM   2869 C CD  . GLN B 1 131 ? 222.318 219.513 265.961 1.00 59.64  ? 388 GLN D CD  1 
ATOM   2870 O OE1 . GLN B 1 131 ? 223.247 220.177 265.505 1.00 61.00  ? 388 GLN D OE1 1 
ATOM   2871 N NE2 . GLN B 1 131 ? 222.497 218.552 266.860 1.00 59.07  ? 388 GLN D NE2 1 
ATOM   2872 N N   . ARG B 1 132 ? 217.195 220.381 264.475 1.00 46.47  ? 389 ARG D N   1 
ATOM   2873 C CA  . ARG B 1 132 ? 215.937 220.095 265.148 1.00 48.04  ? 389 ARG D CA  1 
ATOM   2874 C C   . ARG B 1 132 ? 215.933 218.755 265.872 1.00 47.18  ? 389 ARG D C   1 
ATOM   2875 O O   . ARG B 1 132 ? 214.892 218.363 266.408 1.00 48.47  ? 389 ARG D O   1 
ATOM   2876 C CB  . ARG B 1 132 ? 214.786 220.136 264.140 1.00 45.24  ? 389 ARG D CB  1 
ATOM   2877 C CG  . ARG B 1 132 ? 215.059 221.013 262.932 1.00 40.52  ? 389 ARG D CG  1 
ATOM   2878 C CD  . ARG B 1 132 ? 213.840 221.835 262.560 1.00 43.00  ? 389 ARG D CD  1 
ATOM   2879 N NE  . ARG B 1 132 ? 214.022 222.532 261.294 1.00 46.48  ? 389 ARG D NE  1 
ATOM   2880 C CZ  . ARG B 1 132 ? 213.037 223.061 260.582 1.00 43.89  ? 389 ARG D CZ  1 
ATOM   2881 N NH1 . ARG B 1 132 ? 211.779 222.987 260.982 1.00 43.57  ? 389 ARG D NH1 1 
ATOM   2882 N NH2 . ARG B 1 132 ? 213.321 223.679 259.440 1.00 46.57  ? 389 ARG D NH2 1 
ATOM   2883 N N   . LYS B 1 133 ? 217.060 218.046 265.903 1.00 55.97  ? 390 LYS D N   1 
ATOM   2884 C CA  . LYS B 1 133 ? 217.149 216.732 266.532 1.00 57.23  ? 390 LYS D CA  1 
ATOM   2885 C C   . LYS B 1 133 ? 218.220 216.778 267.613 1.00 50.97  ? 390 LYS D C   1 
ATOM   2886 O O   . LYS B 1 133 ? 219.417 216.785 267.307 1.00 47.25  ? 390 LYS D O   1 
ATOM   2887 C CB  . LYS B 1 133 ? 217.457 215.650 265.498 1.00 49.96  ? 390 LYS D CB  1 
ATOM   2888 C CG  . LYS B 1 133 ? 216.363 215.471 264.462 1.00 49.07  ? 390 LYS D CG  1 
ATOM   2889 C CD  . LYS B 1 133 ? 215.011 215.301 265.129 1.00 51.24  ? 390 LYS D CD  1 
ATOM   2890 C CE  . LYS B 1 133 ? 213.992 214.709 264.177 1.00 50.97  ? 390 LYS D CE  1 
ATOM   2891 N NZ  . LYS B 1 133 ? 213.000 215.726 263.745 1.00 55.51  ? 390 LYS D NZ  1 
ATOM   2892 N N   . GLY B 1 134 ? 217.794 216.802 268.866 1.00 39.76  ? 391 GLY D N   1 
ATOM   2893 C CA  . GLY B 1 134 ? 218.693 216.883 269.993 1.00 39.02  ? 391 GLY D CA  1 
ATOM   2894 C C   . GLY B 1 134 ? 218.683 218.253 270.640 1.00 40.36  ? 391 GLY D C   1 
ATOM   2895 O O   . GLY B 1 134 ? 217.752 219.047 270.484 1.00 33.56  ? 391 GLY D O   1 
ATOM   2896 N N   . TRP B 1 135 ? 219.749 218.529 271.384 1.00 39.66  ? 392 TRP D N   1 
ATOM   2897 C CA  . TRP B 1 135 ? 219.941 219.819 272.031 1.00 35.49  ? 392 TRP D CA  1 
ATOM   2898 C C   . TRP B 1 135 ? 221.069 220.561 271.333 1.00 45.52  ? 392 TRP D C   1 
ATOM   2899 O O   . TRP B 1 135 ? 222.182 220.038 271.215 1.00 45.95  ? 392 TRP D O   1 
ATOM   2900 C CB  . TRP B 1 135 ? 220.258 219.663 273.516 1.00 34.55  ? 392 TRP D CB  1 
ATOM   2901 C CG  . TRP B 1 135 ? 220.625 220.961 274.165 1.00 39.28  ? 392 TRP D CG  1 
ATOM   2902 C CD1 . TRP B 1 135 ? 219.769 221.898 274.659 1.00 36.39  ? 392 TRP D CD1 1 
ATOM   2903 C CD2 . TRP B 1 135 ? 221.946 221.472 274.382 1.00 42.77  ? 392 TRP D CD2 1 
ATOM   2904 N NE1 . TRP B 1 135 ? 220.473 222.959 275.173 1.00 38.20  ? 392 TRP D NE1 1 
ATOM   2905 C CE2 . TRP B 1 135 ? 221.812 222.721 275.016 1.00 37.88  ? 392 TRP D CE2 1 
ATOM   2906 C CE3 . TRP B 1 135 ? 223.230 220.993 274.105 1.00 42.48  ? 392 TRP D CE3 1 
ATOM   2907 C CZ2 . TRP B 1 135 ? 222.908 223.495 275.376 1.00 36.53  ? 392 TRP D CZ2 1 
ATOM   2908 C CZ3 . TRP B 1 135 ? 224.316 221.764 274.464 1.00 33.27  ? 392 TRP D CZ3 1 
ATOM   2909 C CH2 . TRP B 1 135 ? 224.149 223.000 275.091 1.00 32.59  ? 392 TRP D CH2 1 
ATOM   2910 N N   . VAL B 1 136 ? 220.776 221.775 270.876 1.00 51.93  ? 393 VAL D N   1 
ATOM   2911 C CA  . VAL B 1 136 ? 221.768 222.682 270.315 1.00 40.11  ? 393 VAL D CA  1 
ATOM   2912 C C   . VAL B 1 136 ? 221.585 224.040 270.975 1.00 39.71  ? 393 VAL D C   1 
ATOM   2913 O O   . VAL B 1 136 ? 220.455 224.513 271.140 1.00 47.84  ? 393 VAL D O   1 
ATOM   2914 C CB  . VAL B 1 136 ? 221.649 222.784 268.779 1.00 41.63  ? 393 VAL D CB  1 
ATOM   2915 C CG1 . VAL B 1 136 ? 220.235 223.165 268.371 1.00 43.18  ? 393 VAL D CG1 1 
ATOM   2916 C CG2 . VAL B 1 136 ? 222.661 223.775 268.229 1.00 46.61  ? 393 VAL D CG2 1 
ATOM   2917 N N   . LYS B 1 137 ? 222.693 224.650 271.383 1.00 35.29  ? 394 LYS D N   1 
ATOM   2918 C CA  . LYS B 1 137 ? 222.631 225.918 272.092 1.00 37.73  ? 394 LYS D CA  1 
ATOM   2919 C C   . LYS B 1 137 ? 222.029 227.001 271.205 1.00 50.47  ? 394 LYS D C   1 
ATOM   2920 O O   . LYS B 1 137 ? 222.343 227.099 270.016 1.00 61.05  ? 394 LYS D O   1 
ATOM   2921 C CB  . LYS B 1 137 ? 224.025 226.331 272.557 1.00 39.54  ? 394 LYS D CB  1 
ATOM   2922 C CG  . LYS B 1 137 ? 224.038 227.576 273.412 1.00 44.30  ? 394 LYS D CG  1 
ATOM   2923 C CD  . LYS B 1 137 ? 225.383 227.784 274.072 1.00 39.32  ? 394 LYS D CD  1 
ATOM   2924 C CE  . LYS B 1 137 ? 225.218 228.387 275.450 1.00 40.93  ? 394 LYS D CE  1 
ATOM   2925 N NZ  . LYS B 1 137 ? 226.516 228.858 275.999 1.00 45.94  ? 394 LYS D NZ  1 
ATOM   2926 N N   . MET B 1 138 ? 221.150 227.813 271.788 1.00 42.72  ? 395 MET D N   1 
ATOM   2927 C CA  . MET B 1 138 ? 220.480 228.883 271.050 1.00 41.84  ? 395 MET D CA  1 
ATOM   2928 C C   . MET B 1 138 ? 221.325 230.146 271.135 1.00 44.58  ? 395 MET D C   1 
ATOM   2929 O O   . MET B 1 138 ? 221.185 230.958 272.049 1.00 53.78  ? 395 MET D O   1 
ATOM   2930 C CB  . MET B 1 138 ? 219.076 229.110 271.590 1.00 43.72  ? 395 MET D CB  1 
ATOM   2931 C CG  . MET B 1 138 ? 218.011 228.404 270.793 1.00 46.95  ? 395 MET D CG  1 
ATOM   2932 S SD  . MET B 1 138 ? 216.423 228.404 271.620 1.00 57.87  ? 395 MET D SD  1 
ATOM   2933 C CE  . MET B 1 138 ? 215.337 228.395 270.204 1.00 48.32  ? 395 MET D CE  1 
ATOM   2934 N N   . THR B 1 139 ? 222.206 230.314 270.162 1.00 37.14  ? 396 THR D N   1 
ATOM   2935 C CA  . THR B 1 139 ? 223.117 231.441 270.062 1.00 47.18  ? 396 THR D CA  1 
ATOM   2936 C C   . THR B 1 139 ? 223.091 231.981 268.643 1.00 44.71  ? 396 THR D C   1 
ATOM   2937 O O   . THR B 1 139 ? 222.629 231.301 267.720 1.00 47.22  ? 396 THR D O   1 
ATOM   2938 C CB  . THR B 1 139 ? 224.551 231.036 270.438 1.00 43.95  ? 396 THR D CB  1 
ATOM   2939 O OG1 . THR B 1 139 ? 224.936 229.872 269.698 1.00 39.80  ? 396 THR D OG1 1 
ATOM   2940 C CG2 . THR B 1 139 ? 224.661 230.762 271.924 1.00 43.08  ? 396 THR D CG2 1 
ATOM   2941 N N   . PRO B 1 140 ? 223.562 233.213 268.435 1.00 38.62  ? 397 PRO D N   1 
ATOM   2942 C CA  . PRO B 1 140 ? 223.702 233.709 267.058 1.00 39.68  ? 397 PRO D CA  1 
ATOM   2943 C C   . PRO B 1 140 ? 224.614 232.853 266.199 1.00 43.75  ? 397 PRO D C   1 
ATOM   2944 O O   . PRO B 1 140 ? 224.438 232.817 264.975 1.00 51.93  ? 397 PRO D O   1 
ATOM   2945 C CB  . PRO B 1 140 ? 224.272 235.120 267.255 1.00 41.62  ? 397 PRO D CB  1 
ATOM   2946 C CG  . PRO B 1 140 ? 223.827 235.519 268.609 1.00 40.76  ? 397 PRO D CG  1 
ATOM   2947 C CD  . PRO B 1 140 ? 223.837 234.267 269.428 1.00 47.41  ? 397 PRO D CD  1 
ATOM   2948 N N   . GLU B 1 141 ? 225.587 232.166 266.800 1.00 44.76  ? 398 GLU D N   1 
ATOM   2949 C CA  . GLU B 1 141 ? 226.502 231.338 266.020 1.00 43.35  ? 398 GLU D CA  1 
ATOM   2950 C C   . GLU B 1 141 ? 225.766 230.208 265.311 1.00 43.30  ? 398 GLU D C   1 
ATOM   2951 O O   . GLU B 1 141 ? 226.054 229.904 264.149 1.00 46.53  ? 398 GLU D O   1 
ATOM   2952 C CB  . GLU B 1 141 ? 227.599 230.777 266.923 1.00 40.57  ? 398 GLU D CB  1 
ATOM   2953 C CG  . GLU B 1 141 ? 228.798 231.689 267.076 1.00 41.78  ? 398 GLU D CG  1 
ATOM   2954 C CD  . GLU B 1 141 ? 228.643 232.664 268.222 1.00 51.93  ? 398 GLU D CD  1 
ATOM   2955 O OE1 . GLU B 1 141 ? 227.517 232.799 268.741 1.00 58.93  ? 398 GLU D OE1 1 
ATOM   2956 O OE2 . GLU B 1 141 ? 229.648 233.295 268.606 1.00 53.75  ? 398 GLU D OE2 1 
ATOM   2957 N N   . ASN B 1 142 ? 224.821 229.567 265.996 1.00 40.46  ? 399 ASN D N   1 
ATOM   2958 C CA  . ASN B 1 142 ? 224.053 228.499 265.368 1.00 41.41  ? 399 ASN D CA  1 
ATOM   2959 C C   . ASN B 1 142 ? 223.031 229.036 264.378 1.00 39.93  ? 399 ASN D C   1 
ATOM   2960 O O   . ASN B 1 142 ? 222.873 228.471 263.290 1.00 50.31  ? 399 ASN D O   1 
ATOM   2961 C CB  . ASN B 1 142 ? 223.354 227.653 266.432 1.00 34.91  ? 399 ASN D CB  1 
ATOM   2962 C CG  . ASN B 1 142 ? 224.325 227.007 267.389 1.00 36.77  ? 399 ASN D CG  1 
ATOM   2963 O OD1 . ASN B 1 142 ? 225.200 226.246 266.982 1.00 42.74  ? 399 ASN D OD1 1 
ATOM   2964 N ND2 . ASN B 1 142 ? 224.182 227.311 268.670 1.00 45.05  ? 399 ASN D ND2 1 
ATOM   2965 N N   . GLY B 1 143 ? 222.337 230.114 264.725 1.00 33.08  ? 400 GLY D N   1 
ATOM   2966 C CA  . GLY B 1 143 ? 221.324 230.659 263.847 1.00 41.10  ? 400 GLY D CA  1 
ATOM   2967 C C   . GLY B 1 143 ? 220.093 231.144 264.581 1.00 44.59  ? 400 GLY D C   1 
ATOM   2968 O O   . GLY B 1 143 ? 219.185 231.712 263.971 1.00 48.37  ? 400 GLY D O   1 
ATOM   2969 N N   . PHE B 1 144 ? 220.052 230.932 265.892 1.00 50.77  ? 401 PHE D N   1 
ATOM   2970 C CA  . PHE B 1 144 ? 218.927 231.353 266.723 1.00 43.51  ? 401 PHE D CA  1 
ATOM   2971 C C   . PHE B 1 144 ? 219.230 232.743 267.271 1.00 42.05  ? 401 PHE D C   1 
ATOM   2972 O O   . PHE B 1 144 ? 219.967 232.890 268.248 1.00 48.17  ? 401 PHE D O   1 
ATOM   2973 C CB  . PHE B 1 144 ? 218.677 230.365 267.857 1.00 53.22  ? 401 PHE D CB  1 
ATOM   2974 C CG  . PHE B 1 144 ? 218.575 228.931 267.418 1.00 53.97  ? 401 PHE D CG  1 
ATOM   2975 C CD1 . PHE B 1 144 ? 219.709 228.150 267.280 1.00 48.24  ? 401 PHE D CD1 1 
ATOM   2976 C CD2 . PHE B 1 144 ? 217.342 228.358 267.170 1.00 44.81  ? 401 PHE D CD2 1 
ATOM   2977 C CE1 . PHE B 1 144 ? 219.614 226.835 266.889 1.00 45.92  ? 401 PHE D CE1 1 
ATOM   2978 C CE2 . PHE B 1 144 ? 217.243 227.042 266.782 1.00 40.61  ? 401 PHE D CE2 1 
ATOM   2979 C CZ  . PHE B 1 144 ? 218.380 226.280 266.641 1.00 49.48  ? 401 PHE D CZ  1 
ATOM   2980 N N   . TRP B 1 145 ? 218.664 233.764 266.631 1.00 47.14  ? 402 TRP D N   1 
ATOM   2981 C CA  . TRP B 1 145 ? 218.715 235.134 267.137 1.00 50.92  ? 402 TRP D CA  1 
ATOM   2982 C C   . TRP B 1 145 ? 217.419 235.366 267.906 1.00 49.94  ? 402 TRP D C   1 
ATOM   2983 O O   . TRP B 1 145 ? 216.374 235.686 267.339 1.00 52.88  ? 402 TRP D O   1 
ATOM   2984 C CB  . TRP B 1 145 ? 218.893 236.127 265.993 1.00 44.17  ? 402 TRP D CB  1 
ATOM   2985 C CG  . TRP B 1 145 ? 220.165 235.929 265.239 1.00 44.95  ? 402 TRP D CG  1 
ATOM   2986 C CD1 . TRP B 1 145 ? 221.416 236.295 265.633 1.00 48.15  ? 402 TRP D CD1 1 
ATOM   2987 C CD2 . TRP B 1 145 ? 220.315 235.301 263.962 1.00 45.14  ? 402 TRP D CD2 1 
ATOM   2988 N NE1 . TRP B 1 145 ? 222.337 235.938 264.680 1.00 46.94  ? 402 TRP D NE1 1 
ATOM   2989 C CE2 . TRP B 1 145 ? 221.686 235.325 263.643 1.00 45.83  ? 402 TRP D CE2 1 
ATOM   2990 C CE3 . TRP B 1 145 ? 219.423 234.723 263.056 1.00 45.04  ? 402 TRP D CE3 1 
ATOM   2991 C CZ2 . TRP B 1 145 ? 222.186 234.791 262.461 1.00 43.90  ? 402 TRP D CZ2 1 
ATOM   2992 C CZ3 . TRP B 1 145 ? 219.920 234.195 261.883 1.00 51.32  ? 402 TRP D CZ3 1 
ATOM   2993 C CH2 . TRP B 1 145 ? 221.289 234.233 261.594 1.00 52.82  ? 402 TRP D CH2 1 
ATOM   2994 N N   . THR B 1 146 ? 217.486 235.151 269.221 1.00 41.64  ? 403 THR D N   1 
ATOM   2995 C CA  . THR B 1 146 ? 216.307 235.193 270.074 1.00 46.55  ? 403 THR D CA  1 
ATOM   2996 C C   . THR B 1 146 ? 216.603 235.951 271.362 1.00 47.37  ? 403 THR D C   1 
ATOM   2997 O O   . THR B 1 146 ? 217.757 236.182 271.728 1.00 49.49  ? 403 THR D O   1 
ATOM   2998 C CB  . THR B 1 146 ? 215.795 233.786 270.435 1.00 57.28  ? 403 THR D CB  1 
ATOM   2999 O OG1 . THR B 1 146 ? 216.457 233.327 271.618 1.00 66.28  ? 403 THR D OG1 1 
ATOM   3000 C CG2 . THR B 1 146 ? 216.038 232.792 269.307 1.00 58.28  ? 403 THR D CG2 1 
ATOM   3001 N N   . MET B 1 147 ? 215.525 236.337 272.041 1.00 53.35  ? 404 MET D N   1 
ATOM   3002 C CA  . MET B 1 147 ? 215.594 236.998 273.337 1.00 54.35  ? 404 MET D CA  1 
ATOM   3003 C C   . MET B 1 147 ? 214.269 236.789 274.054 1.00 54.49  ? 404 MET D C   1 
ATOM   3004 O O   . MET B 1 147 ? 213.272 236.388 273.445 1.00 59.42  ? 404 MET D O   1 
ATOM   3005 C CB  . MET B 1 147 ? 215.905 238.491 273.196 1.00 55.80  ? 404 MET D CB  1 
ATOM   3006 C CG  . MET B 1 147 ? 214.675 239.378 273.068 1.00 61.96  ? 404 MET D CG  1 
ATOM   3007 S SD  . MET B 1 147 ? 214.266 240.227 274.602 1.00 71.77  ? 404 MET D SD  1 
ATOM   3008 C CE  . MET B 1 147 ? 215.646 241.356 274.727 1.00 54.07  ? 404 MET D CE  1 
ATOM   3009 N N   . GLY B 1 148 ? 214.261 237.049 275.357 1.00 44.79  ? 405 GLY D N   1 
ATOM   3010 C CA  . GLY B 1 148 ? 213.019 236.947 276.093 1.00 40.71  ? 405 GLY D CA  1 
ATOM   3011 C C   . GLY B 1 148 ? 213.251 236.894 277.589 1.00 47.29  ? 405 GLY D C   1 
ATOM   3012 O O   . GLY B 1 148 ? 214.307 237.276 278.094 1.00 51.79  ? 405 GLY D O   1 
ATOM   3013 N N   . LEU B 1 149 ? 212.243 236.374 278.281 1.00 51.35  ? 406 LEU D N   1 
ATOM   3014 C CA  . LEU B 1 149 ? 212.158 236.458 279.732 1.00 47.41  ? 406 LEU D CA  1 
ATOM   3015 C C   . LEU B 1 149 ? 212.305 235.077 280.356 1.00 56.64  ? 406 LEU D C   1 
ATOM   3016 O O   . LEU B 1 149 ? 211.703 234.107 279.883 1.00 70.56  ? 406 LEU D O   1 
ATOM   3017 C CB  . LEU B 1 149 ? 210.828 237.086 280.146 1.00 48.92  ? 406 LEU D CB  1 
ATOM   3018 C CG  . LEU B 1 149 ? 210.422 237.006 281.612 1.00 46.17  ? 406 LEU D CG  1 
ATOM   3019 C CD1 . LEU B 1 149 ? 211.060 238.139 282.383 1.00 53.31  ? 406 LEU D CD1 1 
ATOM   3020 C CD2 . LEU B 1 149 ? 208.915 237.064 281.734 1.00 50.32  ? 406 LEU D CD2 1 
ATOM   3021 N N   . THR B 1 150 ? 213.103 234.997 281.419 1.00 57.10  ? 407 THR D N   1 
ATOM   3022 C CA  . THR B 1 150 ? 213.305 233.771 282.170 1.00 55.62  ? 407 THR D CA  1 
ATOM   3023 C C   . THR B 1 150 ? 213.393 234.133 283.648 1.00 53.94  ? 407 THR D C   1 
ATOM   3024 O O   . THR B 1 150 ? 213.498 235.308 284.011 1.00 67.72  ? 407 THR D O   1 
ATOM   3025 C CB  . THR B 1 150 ? 214.574 233.041 281.710 1.00 62.84  ? 407 THR D CB  1 
ATOM   3026 O OG1 . THR B 1 150 ? 214.627 233.045 280.280 1.00 68.50  ? 407 THR D OG1 1 
ATOM   3027 C CG2 . THR B 1 150 ? 214.568 231.594 282.170 1.00 61.83  ? 407 THR D CG2 1 
ATOM   3028 N N   . ASP B 1 151 ? 213.334 233.109 284.500 1.00 57.45  ? 408 ASP D N   1 
ATOM   3029 C CA  . ASP B 1 151 ? 213.475 233.262 285.946 1.00 71.33  ? 408 ASP D CA  1 
ATOM   3030 C C   . ASP B 1 151 ? 212.386 234.183 286.500 1.00 68.50  ? 408 ASP D C   1 
ATOM   3031 O O   . ASP B 1 151 ? 212.605 234.986 287.409 1.00 70.59  ? 408 ASP D O   1 
ATOM   3032 C CB  . ASP B 1 151 ? 214.877 233.770 286.305 1.00 73.34  ? 408 ASP D CB  1 
ATOM   3033 C CG  . ASP B 1 151 ? 215.215 233.574 287.770 1.00 76.99  ? 408 ASP D CG  1 
ATOM   3034 O OD1 . ASP B 1 151 ? 214.737 232.585 288.365 1.00 76.77  ? 408 ASP D OD1 1 
ATOM   3035 O OD2 . ASP B 1 151 ? 215.959 234.409 288.325 1.00 72.55  ? 408 ASP D OD2 1 
ATOM   3036 N N   . GLY B 1 152 ? 211.197 234.051 285.925 1.00 60.47  ? 409 GLY D N   1 
ATOM   3037 C CA  . GLY B 1 152 ? 210.073 234.855 286.350 1.00 64.11  ? 409 GLY D CA  1 
ATOM   3038 C C   . GLY B 1 152 ? 210.139 236.282 285.850 1.00 71.90  ? 409 GLY D C   1 
ATOM   3039 O O   . GLY B 1 152 ? 209.330 236.689 285.011 1.00 75.06  ? 409 GLY D O   1 
ATOM   3040 N N   . ASN B 1 153 ? 211.108 237.056 286.347 1.00 64.23  ? 410 ASN D N   1 
ATOM   3041 C CA  . ASN B 1 153 ? 211.160 238.474 286.016 1.00 58.71  ? 410 ASN D CA  1 
ATOM   3042 C C   . ASN B 1 153 ? 212.543 238.934 285.564 1.00 58.72  ? 410 ASN D C   1 
ATOM   3043 O O   . ASN B 1 153 ? 212.923 240.075 285.847 1.00 65.42  ? 410 ASN D O   1 
ATOM   3044 C CB  . ASN B 1 153 ? 210.717 239.317 287.211 1.00 65.71  ? 410 ASN D CB  1 
ATOM   3045 C CG  . ASN B 1 153 ? 211.443 238.938 288.485 1.00 71.62  ? 410 ASN D CG  1 
ATOM   3046 O OD1 . ASN B 1 153 ? 212.228 237.991 288.506 1.00 70.85  ? 410 ASN D OD1 1 
ATOM   3047 N ND2 . ASN B 1 153 ? 211.184 239.678 289.556 1.00 70.85  ? 410 ASN D ND2 1 
ATOM   3048 N N   . LYS B 1 154 ? 213.306 238.092 284.876 1.00 49.17  ? 411 LYS D N   1 
ATOM   3049 C CA  . LYS B 1 154 ? 214.634 238.461 284.407 1.00 52.69  ? 411 LYS D CA  1 
ATOM   3050 C C   . LYS B 1 154 ? 214.662 238.446 282.887 1.00 57.08  ? 411 LYS D C   1 
ATOM   3051 O O   . LYS B 1 154 ? 214.386 237.416 282.267 1.00 62.24  ? 411 LYS D O   1 
ATOM   3052 C CB  . LYS B 1 154 ? 215.695 237.515 284.969 1.00 53.75  ? 411 LYS D CB  1 
ATOM   3053 C CG  . LYS B 1 154 ? 217.114 237.936 284.660 1.00 50.59  ? 411 LYS D CG  1 
ATOM   3054 C CD  . LYS B 1 154 ? 218.108 237.125 285.464 1.00 54.55  ? 411 LYS D CD  1 
ATOM   3055 C CE  . LYS B 1 154 ? 217.858 235.640 285.302 1.00 55.51  ? 411 LYS D CE  1 
ATOM   3056 N NZ  . LYS B 1 154 ? 217.809 235.246 283.868 1.00 57.88  ? 411 LYS D NZ  1 
ATOM   3057 N N   . TYR B 1 155 ? 215.011 239.579 282.289 1.00 51.08  ? 412 TYR D N   1 
ATOM   3058 C CA  . TYR B 1 155 ? 215.030 239.719 280.840 1.00 51.87  ? 412 TYR D CA  1 
ATOM   3059 C C   . TYR B 1 155 ? 216.438 239.457 280.330 1.00 46.80  ? 412 TYR D C   1 
ATOM   3060 O O   . TYR B 1 155 ? 217.411 239.972 280.889 1.00 45.21  ? 412 TYR D O   1 
ATOM   3061 C CB  . TYR B 1 155 ? 214.551 241.107 280.419 1.00 46.06  ? 412 TYR D CB  1 
ATOM   3062 C CG  . TYR B 1 155 ? 213.081 241.323 280.681 1.00 47.49  ? 412 TYR D CG  1 
ATOM   3063 C CD1 . TYR B 1 155 ? 212.632 241.711 281.935 1.00 50.91  ? 412 TYR D CD1 1 
ATOM   3064 C CD2 . TYR B 1 155 ? 212.143 241.127 279.682 1.00 42.51  ? 412 TYR D CD2 1 
ATOM   3065 C CE1 . TYR B 1 155 ? 211.291 241.905 282.184 1.00 45.00  ? 412 TYR D CE1 1 
ATOM   3066 C CE2 . TYR B 1 155 ? 210.800 241.315 279.923 1.00 51.54  ? 412 TYR D CE2 1 
ATOM   3067 C CZ  . TYR B 1 155 ? 210.380 241.705 281.175 1.00 48.98  ? 412 TYR D CZ  1 
ATOM   3068 O OH  . TYR B 1 155 ? 209.043 241.897 281.420 1.00 49.19  ? 412 TYR D OH  1 
ATOM   3069 N N   . ARG B 1 156 ? 216.545 238.663 279.270 1.00 43.29  ? 413 ARG D N   1 
ATOM   3070 C CA  . ARG B 1 156 ? 217.837 238.192 278.809 1.00 46.09  ? 413 ARG D CA  1 
ATOM   3071 C C   . ARG B 1 156 ? 217.830 238.074 277.292 1.00 43.88  ? 413 ARG D C   1 
ATOM   3072 O O   . ARG B 1 156 ? 216.779 237.911 276.661 1.00 43.93  ? 413 ARG D O   1 
ATOM   3073 C CB  . ARG B 1 156 ? 218.182 236.852 279.478 1.00 53.47  ? 413 ARG D CB  1 
ATOM   3074 C CG  . ARG B 1 156 ? 219.630 236.412 279.348 1.00 55.19  ? 413 ARG D CG  1 
ATOM   3075 C CD  . ARG B 1 156 ? 219.822 234.970 279.804 1.00 43.12  ? 413 ARG D CD  1 
ATOM   3076 N NE  . ARG B 1 156 ? 218.871 234.056 279.185 1.00 45.67  ? 413 ARG D NE  1 
ATOM   3077 C CZ  . ARG B 1 156 ? 217.877 233.468 279.834 1.00 43.36  ? 413 ARG D CZ  1 
ATOM   3078 N NH1 . ARG B 1 156 ? 217.707 233.639 281.133 1.00 46.61  ? 413 ARG D NH1 1 
ATOM   3079 N NH2 . ARG B 1 156 ? 217.035 232.689 279.163 1.00 41.88  ? 413 ARG D NH2 1 
ATOM   3080 N N   . THR B 1 157 ? 219.019 238.205 276.714 1.00 44.28  ? 414 THR D N   1 
ATOM   3081 C CA  . THR B 1 157 ? 219.254 237.987 275.297 1.00 42.23  ? 414 THR D CA  1 
ATOM   3082 C C   . THR B 1 157 ? 220.174 236.787 275.134 1.00 50.34  ? 414 THR D C   1 
ATOM   3083 O O   . THR B 1 157 ? 221.189 236.667 275.834 1.00 54.98  ? 414 THR D O   1 
ATOM   3084 C CB  . THR B 1 157 ? 219.876 239.214 274.628 1.00 45.02  ? 414 THR D CB  1 
ATOM   3085 O OG1 . THR B 1 157 ? 221.294 239.205 274.831 1.00 47.56  ? 414 THR D OG1 1 
ATOM   3086 C CG2 . THR B 1 157 ? 219.298 240.489 275.210 1.00 46.42  ? 414 THR D CG2 1 
ATOM   3087 N N   . LEU B 1 158 ? 219.807 235.903 274.207 1.00 54.85  ? 415 LEU D N   1 
ATOM   3088 C CA  . LEU B 1 158 ? 220.495 234.629 274.018 1.00 52.80  ? 415 LEU D CA  1 
ATOM   3089 C C   . LEU B 1 158 ? 221.728 234.851 273.149 1.00 55.09  ? 415 LEU D C   1 
ATOM   3090 O O   . LEU B 1 158 ? 221.736 234.619 271.939 1.00 58.15  ? 415 LEU D O   1 
ATOM   3091 C CB  . LEU B 1 158 ? 219.554 233.599 273.408 1.00 50.44  ? 415 LEU D CB  1 
ATOM   3092 C CG  . LEU B 1 158 ? 218.372 233.150 274.266 1.00 42.91  ? 415 LEU D CG  1 
ATOM   3093 C CD1 . LEU B 1 158 ? 217.970 231.734 273.903 1.00 49.34  ? 415 LEU D CD1 1 
ATOM   3094 C CD2 . LEU B 1 158 ? 218.696 233.247 275.745 1.00 48.88  ? 415 LEU D CD2 1 
ATOM   3095 N N   . THR B 1 159 ? 222.789 235.310 273.792 1.00 50.80  ? 416 THR D N   1 
ATOM   3096 C CA  . THR B 1 159 ? 224.092 235.462 273.175 1.00 48.74  ? 416 THR D CA  1 
ATOM   3097 C C   . THR B 1 159 ? 225.049 234.440 273.779 1.00 52.87  ? 416 THR D C   1 
ATOM   3098 O O   . THR B 1 159 ? 224.654 233.581 274.574 1.00 57.42  ? 416 THR D O   1 
ATOM   3099 C CB  . THR B 1 159 ? 224.598 236.894 273.353 1.00 54.67  ? 416 THR D CB  1 
ATOM   3100 O OG1 . THR B 1 159 ? 224.358 237.320 274.699 1.00 55.84  ? 416 THR D OG1 1 
ATOM   3101 C CG2 . THR B 1 159 ? 223.883 237.829 272.397 1.00 54.80  ? 416 THR D CG2 1 
ATOM   3102 N N   . GLU B 1 160 ? 226.318 234.525 273.392 1.00 68.48  ? 417 GLU D N   1 
ATOM   3103 C CA  . GLU B 1 160 ? 227.362 233.665 273.944 1.00 68.02  ? 417 GLU D CA  1 
ATOM   3104 C C   . GLU B 1 160 ? 228.428 234.541 274.587 1.00 73.55  ? 417 GLU D C   1 
ATOM   3105 O O   . GLU B 1 160 ? 229.302 235.076 273.882 1.00 81.66  ? 417 GLU D O   1 
ATOM   3106 C CB  . GLU B 1 160 ? 227.966 232.774 272.866 1.00 68.22  ? 417 GLU D CB  1 
ATOM   3107 C CG  . GLU B 1 160 ? 229.081 231.870 273.363 1.00 74.05  ? 417 GLU D CG  1 
ATOM   3108 C CD  . GLU B 1 160 ? 228.560 230.621 274.044 1.00 82.61  ? 417 GLU D CD  1 
ATOM   3109 O OE1 . GLU B 1 160 ? 227.328 230.413 274.045 1.00 84.62  ? 417 GLU D OE1 1 
ATOM   3110 O OE2 . GLU B 1 160 ? 229.381 229.846 274.580 1.00 85.14  ? 417 GLU D OE2 1 
ATOM   3111 N N   . PRO B 1 161 ? 228.396 234.721 275.914 1.00 58.57  ? 418 PRO D N   1 
ATOM   3112 C CA  . PRO B 1 161 ? 227.429 234.187 276.882 1.00 53.78  ? 418 PRO D CA  1 
ATOM   3113 C C   . PRO B 1 161 ? 226.116 234.960 276.899 1.00 56.01  ? 418 PRO D C   1 
ATOM   3114 O O   . PRO B 1 161 ? 226.030 236.063 276.369 1.00 62.05  ? 418 PRO D O   1 
ATOM   3115 C CB  . PRO B 1 161 ? 228.179 234.319 278.211 1.00 54.61  ? 418 PRO D CB  1 
ATOM   3116 C CG  . PRO B 1 161 ? 229.022 235.541 278.024 1.00 52.59  ? 418 PRO D CG  1 
ATOM   3117 C CD  . PRO B 1 161 ? 229.452 235.505 276.579 1.00 56.58  ? 418 PRO D CD  1 
ATOM   3118 N N   . ARG B 1 162 ? 225.078 234.388 277.504 1.00 45.61  ? 419 ARG D N   1 
ATOM   3119 C CA  . ARG B 1 162 ? 223.780 235.043 277.566 1.00 40.02  ? 419 ARG D CA  1 
ATOM   3120 C C   . ARG B 1 162 ? 223.875 236.325 278.383 1.00 40.29  ? 419 ARG D C   1 
ATOM   3121 O O   . ARG B 1 162 ? 224.578 236.379 279.396 1.00 48.92  ? 419 ARG D O   1 
ATOM   3122 C CB  . ARG B 1 162 ? 222.749 234.100 278.179 1.00 38.29  ? 419 ARG D CB  1 
ATOM   3123 C CG  . ARG B 1 162 ? 222.049 233.205 277.177 1.00 42.09  ? 419 ARG D CG  1 
ATOM   3124 C CD  . ARG B 1 162 ? 222.849 231.946 276.904 1.00 39.97  ? 419 ARG D CD  1 
ATOM   3125 N NE  . ARG B 1 162 ? 221.999 230.860 276.433 1.00 31.07  ? 419 ARG D NE  1 
ATOM   3126 C CZ  . ARG B 1 162 ? 221.631 230.692 275.172 1.00 36.45  ? 419 ARG D CZ  1 
ATOM   3127 N NH1 . ARG B 1 162 ? 222.025 231.522 274.221 1.00 39.52  ? 419 ARG D NH1 1 
ATOM   3128 N NH2 . ARG B 1 162 ? 220.846 229.667 274.856 1.00 42.89  ? 419 ARG D NH2 1 
ATOM   3129 N N   . THR B 1 163 ? 223.169 237.364 277.943 1.00 37.15  ? 420 THR D N   1 
ATOM   3130 C CA  . THR B 1 163 ? 223.348 238.697 278.507 1.00 39.16  ? 420 THR D CA  1 
ATOM   3131 C C   . THR B 1 163 ? 222.070 239.179 279.177 1.00 42.17  ? 420 THR D C   1 
ATOM   3132 O O   . THR B 1 163 ? 221.007 239.206 278.550 1.00 46.61  ? 420 THR D O   1 
ATOM   3133 C CB  . THR B 1 163 ? 223.782 239.692 277.429 1.00 45.71  ? 420 THR D CB  1 
ATOM   3134 O OG1 . THR B 1 163 ? 225.093 239.350 276.964 1.00 46.28  ? 420 THR D OG1 1 
ATOM   3135 C CG2 . THR B 1 163 ? 223.809 241.102 277.987 1.00 46.84  ? 420 THR D CG2 1 
ATOM   3136 N N   . ASN B 1 164 ? 222.180 239.571 280.445 1.00 44.12  ? 421 ASN D N   1 
ATOM   3137 C CA  . ASN B 1 164 ? 221.051 240.169 281.145 1.00 44.05  ? 421 ASN D CA  1 
ATOM   3138 C C   . ASN B 1 164 ? 220.783 241.564 280.601 1.00 48.61  ? 421 ASN D C   1 
ATOM   3139 O O   . ASN B 1 164 ? 221.707 242.296 280.240 1.00 49.63  ? 421 ASN D O   1 
ATOM   3140 C CB  . ASN B 1 164 ? 221.319 240.235 282.648 1.00 46.63  ? 421 ASN D CB  1 
ATOM   3141 C CG  . ASN B 1 164 ? 222.151 239.071 283.147 1.00 54.26  ? 421 ASN D CG  1 
ATOM   3142 O OD1 . ASN B 1 164 ? 221.758 237.912 283.018 1.00 56.57  ? 421 ASN D OD1 1 
ATOM   3143 N ND2 . ASN B 1 164 ? 223.307 239.375 283.721 1.00 52.45  ? 421 ASN D ND2 1 
ATOM   3144 N N   . LEU B 1 165 ? 219.509 241.934 280.545 1.00 51.27  ? 422 LEU D N   1 
ATOM   3145 C CA  . LEU B 1 165 ? 219.086 243.199 279.968 1.00 49.29  ? 422 LEU D CA  1 
ATOM   3146 C C   . LEU B 1 165 ? 218.316 243.987 281.013 1.00 44.80  ? 422 LEU D C   1 
ATOM   3147 O O   . LEU B 1 165 ? 217.368 243.470 281.613 1.00 50.50  ? 422 LEU D O   1 
ATOM   3148 C CB  . LEU B 1 165 ? 218.225 242.963 278.728 1.00 47.71  ? 422 LEU D CB  1 
ATOM   3149 C CG  . LEU B 1 165 ? 218.227 244.060 277.671 1.00 52.30  ? 422 LEU D CG  1 
ATOM   3150 C CD1 . LEU B 1 165 ? 219.388 243.862 276.717 1.00 52.79  ? 422 LEU D CD1 1 
ATOM   3151 C CD2 . LEU B 1 165 ? 216.912 244.054 276.923 1.00 52.40  ? 422 LEU D CD2 1 
ATOM   3152 N N   . LYS B 1 166 ? 218.724 245.231 281.233 1.00 39.64  ? 423 LYS D N   1 
ATOM   3153 C CA  . LYS B 1 166 ? 218.070 246.097 282.201 1.00 47.87  ? 423 LYS D CA  1 
ATOM   3154 C C   . LYS B 1 166 ? 216.942 246.849 281.509 1.00 53.40  ? 423 LYS D C   1 
ATOM   3155 O O   . LYS B 1 166 ? 217.186 247.633 280.587 1.00 54.08  ? 423 LYS D O   1 
ATOM   3156 C CB  . LYS B 1 166 ? 219.068 247.071 282.822 1.00 51.79  ? 423 LYS D CB  1 
ATOM   3157 C CG  . LYS B 1 166 ? 220.121 246.404 283.683 1.00 53.24  ? 423 LYS D CG  1 
ATOM   3158 C CD  . LYS B 1 166 ? 220.720 247.383 284.672 1.00 55.12  ? 423 LYS D CD  1 
ATOM   3159 C CE  . LYS B 1 166 ? 219.692 247.824 285.697 1.00 54.64  ? 423 LYS D CE  1 
ATOM   3160 N NZ  . LYS B 1 166 ? 218.814 246.698 286.116 1.00 55.02  ? 423 LYS D NZ  1 
ATOM   3161 N N   . LEU B 1 167 ? 215.713 246.605 281.951 1.00 54.40  ? 424 LEU D N   1 
ATOM   3162 C CA  . LEU B 1 167 ? 214.566 247.275 281.380 1.00 55.48  ? 424 LEU D CA  1 
ATOM   3163 C C   . LEU B 1 167 ? 213.930 248.203 282.405 1.00 56.39  ? 424 LEU D C   1 
ATOM   3164 O O   . LEU B 1 167 ? 213.747 247.816 283.563 1.00 57.36  ? 424 LEU D O   1 
ATOM   3165 C CB  . LEU B 1 167 ? 213.522 246.264 280.891 1.00 49.18  ? 424 LEU D CB  1 
ATOM   3166 C CG  . LEU B 1 167 ? 213.893 245.483 279.632 1.00 46.33  ? 424 LEU D CG  1 
ATOM   3167 C CD1 . LEU B 1 167 ? 212.659 244.856 279.021 1.00 49.38  ? 424 LEU D CD1 1 
ATOM   3168 C CD2 . LEU B 1 167 ? 214.587 246.384 278.628 1.00 53.26  ? 424 LEU D CD2 1 
ATOM   3169 N N   . PRO B 1 168 ? 213.592 249.435 282.015 1.00 55.28  ? 425 PRO D N   1 
ATOM   3170 C CA  . PRO B 1 168 ? 212.890 250.334 282.936 1.00 62.64  ? 425 PRO D CA  1 
ATOM   3171 C C   . PRO B 1 168 ? 211.397 250.073 283.025 1.00 67.39  ? 425 PRO D C   1 
ATOM   3172 O O   . PRO B 1 168 ? 210.728 250.690 283.864 1.00 69.05  ? 425 PRO D O   1 
ATOM   3173 C CB  . PRO B 1 168 ? 213.169 251.717 282.340 1.00 61.77  ? 425 PRO D CB  1 
ATOM   3174 C CG  . PRO B 1 168 ? 213.277 251.456 280.875 1.00 59.29  ? 425 PRO D CG  1 
ATOM   3175 C CD  . PRO B 1 168 ? 213.863 250.074 280.716 1.00 56.43  ? 425 PRO D CD  1 
ATOM   3176 N N   . LYS B 1 169 ? 210.858 249.186 282.195 1.00 57.60  ? 426 LYS D N   1 
ATOM   3177 C CA  . LYS B 1 169 ? 209.433 248.895 282.185 1.00 54.68  ? 426 LYS D CA  1 
ATOM   3178 C C   . LYS B 1 169 ? 209.251 247.386 282.092 1.00 55.19  ? 426 LYS D C   1 
ATOM   3179 O O   . LYS B 1 169 ? 210.203 246.612 282.227 1.00 53.62  ? 426 LYS D O   1 
ATOM   3180 C CB  . LYS B 1 169 ? 208.738 249.627 281.030 1.00 53.56  ? 426 LYS D CB  1 
ATOM   3181 C CG  . LYS B 1 169 ? 208.015 250.893 281.437 1.00 58.70  ? 426 LYS D CG  1 
ATOM   3182 C CD  . LYS B 1 169 ? 207.155 251.413 280.300 1.00 63.92  ? 426 LYS D CD  1 
ATOM   3183 C CE  . LYS B 1 169 ? 208.014 251.908 279.148 1.00 64.99  ? 426 LYS D CE  1 
ATOM   3184 N NZ  . LYS B 1 169 ? 208.650 253.219 279.453 1.00 61.90  ? 426 LYS D NZ  1 
ATOM   3185 N N   . THR B 1 170 ? 208.010 246.967 281.865 1.00 55.33  ? 427 THR D N   1 
ATOM   3186 C CA  . THR B 1 170 ? 207.671 245.561 281.655 1.00 55.72  ? 427 THR D CA  1 
ATOM   3187 C C   . THR B 1 170 ? 206.990 245.424 280.302 1.00 56.26  ? 427 THR D C   1 
ATOM   3188 O O   . THR B 1 170 ? 205.825 245.830 280.147 1.00 57.38  ? 427 THR D O   1 
ATOM   3189 C CB  . THR B 1 170 ? 206.761 245.045 282.767 1.00 55.26  ? 427 THR D CB  1 
ATOM   3190 O OG1 . THR B 1 170 ? 207.461 245.091 284.016 1.00 56.54  ? 427 THR D OG1 1 
ATOM   3191 C CG2 . THR B 1 170 ? 206.334 243.616 282.486 1.00 54.37  ? 427 THR D CG2 1 
ATOM   3192 N N   . PRO B 1 171 ? 207.663 244.876 279.294 1.00 51.16  ? 428 PRO D N   1 
ATOM   3193 C CA  . PRO B 1 171 ? 207.037 244.764 277.971 1.00 51.24  ? 428 PRO D CA  1 
ATOM   3194 C C   . PRO B 1 171 ? 205.945 243.709 277.921 1.00 51.19  ? 428 PRO D C   1 
ATOM   3195 O O   . PRO B 1 171 ? 206.227 242.508 277.943 1.00 56.81  ? 428 PRO D O   1 
ATOM   3196 C CB  . PRO B 1 171 ? 208.212 244.394 277.057 1.00 50.86  ? 428 PRO D CB  1 
ATOM   3197 C CG  . PRO B 1 171 ? 209.199 243.755 277.952 1.00 51.48  ? 428 PRO D CG  1 
ATOM   3198 C CD  . PRO B 1 171 ? 209.067 244.436 279.282 1.00 53.86  ? 428 PRO D CD  1 
ATOM   3199 N N   . LYS B 1 172 ? 204.690 244.152 277.855 1.00 55.90  ? 429 LYS D N   1 
ATOM   3200 C CA  . LYS B 1 172 ? 203.580 243.233 277.649 1.00 56.31  ? 429 LYS D CA  1 
ATOM   3201 C C   . LYS B 1 172 ? 203.468 242.788 276.196 1.00 60.03  ? 429 LYS D C   1 
ATOM   3202 O O   . LYS B 1 172 ? 202.869 241.742 275.923 1.00 65.90  ? 429 LYS D O   1 
ATOM   3203 C CB  . LYS B 1 172 ? 202.275 243.888 278.118 1.00 56.63  ? 429 LYS D CB  1 
ATOM   3204 C CG  . LYS B 1 172 ? 201.036 243.004 278.062 1.00 57.23  ? 429 LYS D CG  1 
ATOM   3205 C CD  . LYS B 1 172 ? 200.215 243.250 276.806 1.00 63.30  ? 429 LYS D CD  1 
ATOM   3206 C CE  . LYS B 1 172 ? 199.370 244.505 276.938 1.00 67.27  ? 429 LYS D CE  1 
ATOM   3207 N NZ  . LYS B 1 172 ? 198.343 244.595 275.864 1.00 68.01  ? 429 LYS D NZ  1 
ATOM   3208 N N   . LYS B 1 173 ? 204.042 243.547 275.267 1.00 50.59  ? 430 LYS D N   1 
ATOM   3209 C CA  . LYS B 1 173 ? 204.026 243.216 273.851 1.00 53.74  ? 430 LYS D CA  1 
ATOM   3210 C C   . LYS B 1 173 ? 205.412 243.470 273.281 1.00 56.09  ? 430 LYS D C   1 
ATOM   3211 O O   . LYS B 1 173 ? 206.067 244.447 273.653 1.00 62.01  ? 430 LYS D O   1 
ATOM   3212 C CB  . LYS B 1 173 ? 202.983 244.049 273.101 1.00 52.42  ? 430 LYS D CB  1 
ATOM   3213 C CG  . LYS B 1 173 ? 202.445 243.403 271.846 1.00 48.52  ? 430 LYS D CG  1 
ATOM   3214 C CD  . LYS B 1 173 ? 201.643 244.402 271.037 1.00 49.44  ? 430 LYS D CD  1 
ATOM   3215 C CE  . LYS B 1 173 ? 200.195 244.421 271.480 1.00 51.28  ? 430 LYS D CE  1 
ATOM   3216 N NZ  . LYS B 1 173 ? 199.273 244.649 270.336 1.00 55.30  ? 430 LYS D NZ  1 
ATOM   3217 N N   . VAL B 1 174 ? 205.863 242.594 272.386 1.00 52.37  ? 431 VAL D N   1 
ATOM   3218 C CA  . VAL B 1 174 ? 207.195 242.708 271.802 1.00 54.40  ? 431 VAL D CA  1 
ATOM   3219 C C   . VAL B 1 174 ? 207.078 242.650 270.287 1.00 60.56  ? 431 VAL D C   1 
ATOM   3220 O O   . VAL B 1 174 ? 206.467 241.726 269.744 1.00 68.28  ? 431 VAL D O   1 
ATOM   3221 C CB  . VAL B 1 174 ? 208.141 241.605 272.314 1.00 53.41  ? 431 VAL D CB  1 
ATOM   3222 C CG1 . VAL B 1 174 ? 209.407 241.561 271.479 1.00 50.07  ? 431 VAL D CG1 1 
ATOM   3223 C CG2 . VAL B 1 174 ? 208.473 241.833 273.777 1.00 62.15  ? 431 VAL D CG2 1 
ATOM   3224 N N   . GLY B 1 175 ? 207.674 243.623 269.605 1.00 49.43  ? 432 GLY D N   1 
ATOM   3225 C CA  . GLY B 1 175 ? 207.662 243.677 268.154 1.00 46.59  ? 432 GLY D CA  1 
ATOM   3226 C C   . GLY B 1 175 ? 209.035 243.345 267.596 1.00 48.25  ? 432 GLY D C   1 
ATOM   3227 O O   . GLY B 1 175 ? 210.029 243.976 267.954 1.00 50.34  ? 432 GLY D O   1 
ATOM   3228 N N   . VAL B 1 176 ? 209.074 242.348 266.718 1.00 49.28  ? 433 VAL D N   1 
ATOM   3229 C CA  . VAL B 1 176 ? 210.313 241.896 266.100 1.00 47.01  ? 433 VAL D CA  1 
ATOM   3230 C C   . VAL B 1 176 ? 210.347 242.392 264.664 1.00 53.40  ? 433 VAL D C   1 
ATOM   3231 O O   . VAL B 1 176 ? 209.416 242.137 263.887 1.00 59.88  ? 433 VAL D O   1 
ATOM   3232 C CB  . VAL B 1 176 ? 210.447 240.366 266.156 1.00 42.76  ? 433 VAL D CB  1 
ATOM   3233 C CG1 . VAL B 1 176 ? 211.855 239.952 265.781 1.00 43.43  ? 433 VAL D CG1 1 
ATOM   3234 C CG2 . VAL B 1 176 ? 210.088 239.857 267.539 1.00 49.39  ? 433 VAL D CG2 1 
ATOM   3235 N N   . PHE B 1 177 ? 211.413 243.106 264.319 1.00 53.14  ? 434 PHE D N   1 
ATOM   3236 C CA  . PHE B 1 177 ? 211.622 243.657 262.990 1.00 53.25  ? 434 PHE D CA  1 
ATOM   3237 C C   . PHE B 1 177 ? 212.869 243.033 262.384 1.00 53.84  ? 434 PHE D C   1 
ATOM   3238 O O   . PHE B 1 177 ? 213.939 243.048 263.004 1.00 57.24  ? 434 PHE D O   1 
ATOM   3239 C CB  . PHE B 1 177 ? 211.781 245.178 263.040 1.00 51.07  ? 434 PHE D CB  1 
ATOM   3240 C CG  . PHE B 1 177 ? 210.804 245.863 263.945 1.00 50.45  ? 434 PHE D CG  1 
ATOM   3241 C CD1 . PHE B 1 177 ? 211.104 246.074 265.275 1.00 55.28  ? 434 PHE D CD1 1 
ATOM   3242 C CD2 . PHE B 1 177 ? 209.587 246.302 263.465 1.00 52.53  ? 434 PHE D CD2 1 
ATOM   3243 C CE1 . PHE B 1 177 ? 210.204 246.701 266.104 1.00 53.93  ? 434 PHE D CE1 1 
ATOM   3244 C CE2 . PHE B 1 177 ? 208.686 246.929 264.292 1.00 50.07  ? 434 PHE D CE2 1 
ATOM   3245 C CZ  . PHE B 1 177 ? 208.996 247.130 265.611 1.00 50.27  ? 434 PHE D CZ  1 
ATOM   3246 N N   . LEU B 1 178 ? 212.727 242.490 261.181 1.00 55.57  ? 435 LEU D N   1 
ATOM   3247 C CA  . LEU B 1 178 ? 213.832 241.917 260.431 1.00 55.20  ? 435 LEU D CA  1 
ATOM   3248 C C   . LEU B 1 178 ? 214.055 242.723 259.161 1.00 57.18  ? 435 LEU D C   1 
ATOM   3249 O O   . LEU B 1 178 ? 213.101 243.067 258.459 1.00 62.81  ? 435 LEU D O   1 
ATOM   3250 C CB  . LEU B 1 178 ? 213.558 240.456 260.075 1.00 55.95  ? 435 LEU D CB  1 
ATOM   3251 C CG  . LEU B 1 178 ? 214.717 239.721 259.408 1.00 57.17  ? 435 LEU D CG  1 
ATOM   3252 C CD1 . LEU B 1 178 ? 215.685 239.222 260.460 1.00 63.45  ? 435 LEU D CD1 1 
ATOM   3253 C CD2 . LEU B 1 178 ? 214.213 238.576 258.552 1.00 54.37  ? 435 LEU D CD2 1 
ATOM   3254 N N   . ASP B 1 179 ? 215.318 243.033 258.878 1.00 63.35  ? 436 ASP D N   1 
ATOM   3255 C CA  . ASP B 1 179 ? 215.685 243.709 257.636 1.00 64.27  ? 436 ASP D CA  1 
ATOM   3256 C C   . ASP B 1 179 ? 216.850 242.926 257.038 1.00 67.85  ? 436 ASP D C   1 
ATOM   3257 O O   . ASP B 1 179 ? 217.986 243.049 257.504 1.00 69.66  ? 436 ASP D O   1 
ATOM   3258 C CB  . ASP B 1 179 ? 216.050 245.166 257.885 1.00 69.30  ? 436 ASP D CB  1 
ATOM   3259 C CG  . ASP B 1 179 ? 215.945 246.016 256.633 1.00 75.98  ? 436 ASP D CG  1 
ATOM   3260 O OD1 . ASP B 1 179 ? 215.852 245.439 255.530 1.00 74.39  ? 436 ASP D OD1 1 
ATOM   3261 O OD2 . ASP B 1 179 ? 215.957 247.259 256.751 1.00 69.99  ? 436 ASP D OD2 1 
ATOM   3262 N N   . TYR B 1 180 ? 216.555 242.123 256.013 1.00 59.82  ? 437 TYR D N   1 
ATOM   3263 C CA  . TYR B 1 180 ? 217.547 241.184 255.496 1.00 60.84  ? 437 TYR D CA  1 
ATOM   3264 C C   . TYR B 1 180 ? 218.737 241.904 254.874 1.00 61.04  ? 437 TYR D C   1 
ATOM   3265 O O   . TYR B 1 180 ? 219.888 241.499 255.075 1.00 59.99  ? 437 TYR D O   1 
ATOM   3266 C CB  . TYR B 1 180 ? 216.895 240.246 254.482 1.00 64.75  ? 437 TYR D CB  1 
ATOM   3267 C CG  . TYR B 1 180 ? 217.551 238.885 254.389 1.00 68.98  ? 437 TYR D CG  1 
ATOM   3268 C CD1 . TYR B 1 180 ? 218.855 238.749 253.931 1.00 64.92  ? 437 TYR D CD1 1 
ATOM   3269 C CD2 . TYR B 1 180 ? 216.866 237.737 254.763 1.00 63.88  ? 437 TYR D CD2 1 
ATOM   3270 C CE1 . TYR B 1 180 ? 219.455 237.511 253.846 1.00 55.97  ? 437 TYR D CE1 1 
ATOM   3271 C CE2 . TYR B 1 180 ? 217.458 236.497 254.678 1.00 58.76  ? 437 TYR D CE2 1 
ATOM   3272 C CZ  . TYR B 1 180 ? 218.752 236.390 254.221 1.00 60.56  ? 437 TYR D CZ  1 
ATOM   3273 O OH  . TYR B 1 180 ? 219.348 235.154 254.137 1.00 72.51  ? 437 TYR D OH  1 
ATOM   3274 N N   . GLU B 1 181 ? 218.483 242.971 254.112 1.00 67.34  ? 438 GLU D N   1 
ATOM   3275 C CA  . GLU B 1 181 ? 219.558 243.628 253.373 1.00 66.84  ? 438 GLU D CA  1 
ATOM   3276 C C   . GLU B 1 181 ? 220.568 244.269 254.317 1.00 65.17  ? 438 GLU D C   1 
ATOM   3277 O O   . GLU B 1 181 ? 221.778 244.053 254.189 1.00 66.70  ? 438 GLU D O   1 
ATOM   3278 C CB  . GLU B 1 181 ? 218.974 244.667 252.415 1.00 70.12  ? 438 GLU D CB  1 
ATOM   3279 C CG  . GLU B 1 181 ? 217.739 245.385 252.940 1.00 72.75  ? 438 GLU D CG  1 
ATOM   3280 C CD  . GLU B 1 181 ? 216.450 244.657 252.610 1.00 72.27  ? 438 GLU D CD  1 
ATOM   3281 O OE1 . GLU B 1 181 ? 216.388 243.429 252.825 1.00 70.79  ? 438 GLU D OE1 1 
ATOM   3282 O OE2 . GLU B 1 181 ? 215.497 245.313 252.140 1.00 71.97  ? 438 GLU D OE2 1 
ATOM   3283 N N   . THR B 1 182 ? 220.089 245.065 255.274 1.00 55.70  ? 439 THR D N   1 
ATOM   3284 C CA  . THR B 1 182 ? 220.987 245.601 256.290 1.00 52.52  ? 439 THR D CA  1 
ATOM   3285 C C   . THR B 1 182 ? 221.492 244.495 257.203 1.00 55.93  ? 439 THR D C   1 
ATOM   3286 O O   . THR B 1 182 ? 222.608 244.575 257.730 1.00 59.49  ? 439 THR D O   1 
ATOM   3287 C CB  . THR B 1 182 ? 220.287 246.688 257.103 1.00 55.79  ? 439 THR D CB  1 
ATOM   3288 O OG1 . THR B 1 182 ? 219.006 246.215 257.533 1.00 57.29  ? 439 THR D OG1 1 
ATOM   3289 C CG2 . THR B 1 182 ? 220.100 247.941 256.266 1.00 59.10  ? 439 THR D CG2 1 
ATOM   3290 N N   . GLY B 1 183 ? 220.691 243.452 257.393 1.00 59.83  ? 440 GLY D N   1 
ATOM   3291 C CA  . GLY B 1 183 ? 221.088 242.342 258.234 1.00 59.96  ? 440 GLY D CA  1 
ATOM   3292 C C   . GLY B 1 183 ? 221.043 242.642 259.713 1.00 60.10  ? 440 GLY D C   1 
ATOM   3293 O O   . GLY B 1 183 ? 221.871 242.129 260.473 1.00 65.91  ? 440 GLY D O   1 
ATOM   3294 N N   . ASP B 1 184 ? 220.101 243.470 260.146 1.00 52.18  ? 441 ASP D N   1 
ATOM   3295 C CA  . ASP B 1 184 ? 219.987 243.847 261.544 1.00 52.21  ? 441 ASP D CA  1 
ATOM   3296 C C   . ASP B 1 184 ? 218.579 243.540 262.025 1.00 54.54  ? 441 ASP D C   1 
ATOM   3297 O O   . ASP B 1 184 ? 217.600 243.847 261.338 1.00 49.74  ? 441 ASP D O   1 
ATOM   3298 C CB  . ASP B 1 184 ? 220.308 245.328 261.736 1.00 59.88  ? 441 ASP D CB  1 
ATOM   3299 C CG  . ASP B 1 184 ? 221.791 245.583 261.872 1.00 61.72  ? 441 ASP D CG  1 
ATOM   3300 O OD1 . ASP B 1 184 ? 222.579 244.681 261.517 1.00 50.64  ? 441 ASP D OD1 1 
ATOM   3301 O OD2 . ASP B 1 184 ? 222.172 246.679 262.329 1.00 66.56  ? 441 ASP D OD2 1 
ATOM   3302 N N   . ILE B 1 185 ? 218.478 242.937 263.205 1.00 56.05  ? 442 ILE D N   1 
ATOM   3303 C CA  . ILE B 1 185 ? 217.195 242.497 263.745 1.00 49.73  ? 442 ILE D CA  1 
ATOM   3304 C C   . ILE B 1 185 ? 216.950 243.239 265.050 1.00 48.11  ? 442 ILE D C   1 
ATOM   3305 O O   . ILE B 1 185 ? 217.879 243.437 265.840 1.00 52.97  ? 442 ILE D O   1 
ATOM   3306 C CB  . ILE B 1 185 ? 217.146 240.972 263.938 1.00 44.94  ? 442 ILE D CB  1 
ATOM   3307 C CG1 . ILE B 1 185 ? 215.714 240.519 264.217 1.00 51.91  ? 442 ILE D CG1 1 
ATOM   3308 C CG2 . ILE B 1 185 ? 218.092 240.516 265.030 1.00 44.24  ? 442 ILE D CG2 1 
ATOM   3309 C CD1 . ILE B 1 185 ? 215.566 239.033 264.316 1.00 51.34  ? 442 ILE D CD1 1 
ATOM   3310 N N   . SER B 1 186 ? 215.716 243.688 265.260 1.00 49.03  ? 443 SER D N   1 
ATOM   3311 C CA  . SER B 1 186 ? 215.404 244.546 266.394 1.00 46.77  ? 443 SER D CA  1 
ATOM   3312 C C   . SER B 1 186 ? 214.173 244.050 267.138 1.00 44.86  ? 443 SER D C   1 
ATOM   3313 O O   . SER B 1 186 ? 213.197 243.610 266.524 1.00 54.57  ? 443 SER D O   1 
ATOM   3314 C CB  . SER B 1 186 ? 215.185 245.993 265.943 1.00 55.43  ? 443 SER D CB  1 
ATOM   3315 O OG  . SER B 1 186 ? 214.302 246.055 264.839 1.00 57.91  ? 443 SER D OG  1 
ATOM   3316 N N   . PHE B 1 187 ? 214.229 244.121 268.464 1.00 32.40  ? 444 PHE D N   1 
ATOM   3317 C CA  . PHE B 1 187 ? 213.092 243.862 269.334 1.00 37.76  ? 444 PHE D CA  1 
ATOM   3318 C C   . PHE B 1 187 ? 212.728 245.169 270.024 1.00 41.87  ? 444 PHE D C   1 
ATOM   3319 O O   . PHE B 1 187 ? 213.575 245.777 270.690 1.00 51.91  ? 444 PHE D O   1 
ATOM   3320 C CB  . PHE B 1 187 ? 213.417 242.781 270.365 1.00 45.49  ? 444 PHE D CB  1 
ATOM   3321 C CG  . PHE B 1 187 ? 214.010 241.536 269.775 1.00 45.17  ? 444 PHE D CG  1 
ATOM   3322 C CD1 . PHE B 1 187 ? 213.197 240.520 269.307 1.00 47.15  ? 444 PHE D CD1 1 
ATOM   3323 C CD2 . PHE B 1 187 ? 215.381 241.379 269.690 1.00 46.36  ? 444 PHE D CD2 1 
ATOM   3324 C CE1 . PHE B 1 187 ? 213.739 239.376 268.762 1.00 44.85  ? 444 PHE D CE1 1 
ATOM   3325 C CE2 . PHE B 1 187 ? 215.927 240.238 269.146 1.00 44.94  ? 444 PHE D CE2 1 
ATOM   3326 C CZ  . PHE B 1 187 ? 215.105 239.235 268.681 1.00 42.04  ? 444 PHE D CZ  1 
ATOM   3327 N N   . TYR B 1 188 ? 211.476 245.593 269.860 1.00 45.17  ? 445 TYR D N   1 
ATOM   3328 C CA  . TYR B 1 188 ? 210.963 246.835 270.415 1.00 45.87  ? 445 TYR D CA  1 
ATOM   3329 C C   . TYR B 1 188 ? 209.824 246.543 271.383 1.00 46.14  ? 445 TYR D C   1 
ATOM   3330 O O   . TYR B 1 188 ? 209.130 245.528 271.275 1.00 52.38  ? 445 TYR D O   1 
ATOM   3331 C CB  . TYR B 1 188 ? 210.439 247.778 269.323 1.00 45.65  ? 445 TYR D CB  1 
ATOM   3332 C CG  . TYR B 1 188 ? 211.481 248.576 268.573 1.00 46.85  ? 445 TYR D CG  1 
ATOM   3333 C CD1 . TYR B 1 188 ? 212.781 248.117 268.440 1.00 50.29  ? 445 TYR D CD1 1 
ATOM   3334 C CD2 . TYR B 1 188 ? 211.150 249.784 267.976 1.00 39.88  ? 445 TYR D CD2 1 
ATOM   3335 C CE1 . TYR B 1 188 ? 213.724 248.844 267.746 1.00 51.05  ? 445 TYR D CE1 1 
ATOM   3336 C CE2 . TYR B 1 188 ? 212.085 250.516 267.281 1.00 41.61  ? 445 TYR D CE2 1 
ATOM   3337 C CZ  . TYR B 1 188 ? 213.370 250.041 267.170 1.00 48.76  ? 445 TYR D CZ  1 
ATOM   3338 O OH  . TYR B 1 188 ? 214.307 250.769 266.478 1.00 52.50  ? 445 TYR D OH  1 
ATOM   3339 N N   . ASN B 1 189 ? 209.627 247.467 272.319 1.00 49.31  ? 446 ASN D N   1 
ATOM   3340 C CA  . ASN B 1 189 ? 208.515 247.410 273.266 1.00 56.37  ? 446 ASN D CA  1 
ATOM   3341 C C   . ASN B 1 189 ? 207.303 248.024 272.579 1.00 56.83  ? 446 ASN D C   1 
ATOM   3342 O O   . ASN B 1 189 ? 207.126 249.242 272.552 1.00 61.52  ? 446 ASN D O   1 
ATOM   3343 C CB  . ASN B 1 189 ? 208.876 248.139 274.555 1.00 59.44  ? 446 ASN D CB  1 
ATOM   3344 C CG  . ASN B 1 189 ? 207.901 247.865 275.678 1.00 58.33  ? 446 ASN D CG  1 
ATOM   3345 O OD1 . ASN B 1 189 ? 206.792 247.386 275.453 1.00 59.08  ? 446 ASN D OD1 1 
ATOM   3346 N ND2 . ASN B 1 189 ? 208.312 248.174 276.900 1.00 54.68  ? 446 ASN D ND2 1 
ATOM   3347 N N   . ALA B 1 190 ? 206.450 247.167 272.021 1.00 56.02  ? 447 ALA D N   1 
ATOM   3348 C CA  . ALA B 1 190 ? 205.328 247.619 271.208 1.00 58.89  ? 447 ALA D CA  1 
ATOM   3349 C C   . ALA B 1 190 ? 204.245 248.287 272.045 1.00 58.99  ? 447 ALA D C   1 
ATOM   3350 O O   . ALA B 1 190 ? 203.306 248.874 271.499 1.00 52.93  ? 447 ALA D O   1 
ATOM   3351 C CB  . ALA B 1 190 ? 204.735 246.448 270.423 1.00 61.05  ? 447 ALA D CB  1 
ATOM   3352 N N   . VAL B 1 191 ? 204.355 248.189 273.368 1.00 58.24  ? 448 VAL D N   1 
ATOM   3353 C CA  . VAL B 1 191 ? 203.396 248.857 274.241 1.00 54.87  ? 448 VAL D CA  1 
ATOM   3354 C C   . VAL B 1 191 ? 203.560 250.368 274.164 1.00 59.13  ? 448 VAL D C   1 
ATOM   3355 O O   . VAL B 1 191 ? 202.578 251.109 274.042 1.00 63.46  ? 448 VAL D O   1 
ATOM   3356 C CB  . VAL B 1 191 ? 203.543 248.349 275.686 1.00 57.10  ? 448 VAL D CB  1 
ATOM   3357 C CG1 . VAL B 1 191 ? 202.398 248.860 276.542 1.00 55.75  ? 448 VAL D CG1 1 
ATOM   3358 C CG2 . VAL B 1 191 ? 203.595 246.834 275.711 1.00 58.83  ? 448 VAL D CG2 1 
ATOM   3359 N N   . ASP B 1 192 ? 204.801 250.849 274.232 1.00 59.99  ? 449 ASP D N   1 
ATOM   3360 C CA  . ASP B 1 192 ? 205.081 252.278 274.257 1.00 56.13  ? 449 ASP D CA  1 
ATOM   3361 C C   . ASP B 1 192 ? 206.072 252.708 273.183 1.00 57.91  ? 449 ASP D C   1 
ATOM   3362 O O   . ASP B 1 192 ? 206.470 253.877 273.157 1.00 65.74  ? 449 ASP D O   1 
ATOM   3363 C CB  . ASP B 1 192 ? 205.599 252.690 275.637 1.00 57.13  ? 449 ASP D CB  1 
ATOM   3364 C CG  . ASP B 1 192 ? 204.614 252.380 276.741 1.00 63.41  ? 449 ASP D CG  1 
ATOM   3365 O OD1 . ASP B 1 192 ? 203.395 252.419 276.477 1.00 66.79  ? 449 ASP D OD1 1 
ATOM   3366 O OD2 . ASP B 1 192 ? 205.055 252.097 277.873 1.00 64.11  ? 449 ASP D OD2 1 
ATOM   3367 N N   . GLY B 1 193 ? 206.483 251.802 272.303 1.00 56.87  ? 450 GLY D N   1 
ATOM   3368 C CA  . GLY B 1 193 ? 207.375 252.152 271.221 1.00 56.38  ? 450 GLY D CA  1 
ATOM   3369 C C   . GLY B 1 193 ? 208.839 252.231 271.586 1.00 61.88  ? 450 GLY D C   1 
ATOM   3370 O O   . GLY B 1 193 ? 209.652 252.589 270.725 1.00 66.61  ? 450 GLY D O   1 
ATOM   3371 N N   . SER B 1 194 ? 209.206 251.914 272.823 1.00 49.00  ? 451 SER D N   1 
ATOM   3372 C CA  . SER B 1 194 ? 210.605 251.963 273.215 1.00 46.99  ? 451 SER D CA  1 
ATOM   3373 C C   . SER B 1 194 ? 211.388 250.833 272.552 1.00 50.16  ? 451 SER D C   1 
ATOM   3374 O O   . SER B 1 194 ? 210.825 249.859 272.047 1.00 55.53  ? 451 SER D O   1 
ATOM   3375 C CB  . SER B 1 194 ? 210.743 251.876 274.733 1.00 46.57  ? 451 SER D CB  1 
ATOM   3376 O OG  . SER B 1 194 ? 211.942 251.216 275.093 1.00 51.25  ? 451 SER D OG  1 
ATOM   3377 N N   . HIS B 1 195 ? 212.709 250.977 272.557 1.00 37.39  ? 452 HIS D N   1 
ATOM   3378 C CA  . HIS B 1 195 ? 213.608 250.018 271.931 1.00 36.81  ? 452 HIS D CA  1 
ATOM   3379 C C   . HIS B 1 195 ? 214.198 249.104 272.996 1.00 41.17  ? 452 HIS D C   1 
ATOM   3380 O O   . HIS B 1 195 ? 214.768 249.581 273.982 1.00 39.55  ? 452 HIS D O   1 
ATOM   3381 C CB  . HIS B 1 195 ? 214.716 250.742 271.166 1.00 38.08  ? 452 HIS D CB  1 
ATOM   3382 C CG  . HIS B 1 195 ? 215.949 249.921 270.954 1.00 33.94  ? 452 HIS D CG  1 
ATOM   3383 N ND1 . HIS B 1 195 ? 217.010 249.933 271.832 1.00 35.91  ? 452 HIS D ND1 1 
ATOM   3384 C CD2 . HIS B 1 195 ? 216.297 249.077 269.954 1.00 25.94  ? 452 HIS D CD2 1 
ATOM   3385 C CE1 . HIS B 1 195 ? 217.956 249.125 271.387 1.00 39.23  ? 452 HIS D CE1 1 
ATOM   3386 N NE2 . HIS B 1 195 ? 217.548 248.595 270.249 1.00 34.25  ? 452 HIS D NE2 1 
ATOM   3387 N N   . ILE B 1 196 ? 214.058 247.795 272.793 1.00 51.58  ? 453 ILE D N   1 
ATOM   3388 C CA  . ILE B 1 196 ? 214.487 246.810 273.779 1.00 44.57  ? 453 ILE D CA  1 
ATOM   3389 C C   . ILE B 1 196 ? 215.896 246.333 273.456 1.00 41.66  ? 453 ILE D C   1 
ATOM   3390 O O   . ILE B 1 196 ? 216.812 246.475 274.273 1.00 39.10  ? 453 ILE D O   1 
ATOM   3391 C CB  . ILE B 1 196 ? 213.506 245.625 273.846 1.00 37.55  ? 453 ILE D CB  1 
ATOM   3392 C CG1 . ILE B 1 196 ? 212.118 246.102 274.273 1.00 37.91  ? 453 ILE D CG1 1 
ATOM   3393 C CG2 . ILE B 1 196 ? 214.013 244.575 274.807 1.00 43.46  ? 453 ILE D CG2 1 
ATOM   3394 C CD1 . ILE B 1 196 ? 211.164 244.980 274.614 1.00 35.72  ? 453 ILE D CD1 1 
ATOM   3395 N N   . HIS B 1 197 ? 216.084 245.768 272.266 1.00 45.18  ? 454 HIS D N   1 
ATOM   3396 C CA  . HIS B 1 197 ? 217.398 245.257 271.895 1.00 39.59  ? 454 HIS D CA  1 
ATOM   3397 C C   . HIS B 1 197 ? 217.501 245.214 270.378 1.00 48.36  ? 454 HIS D C   1 
ATOM   3398 O O   . HIS B 1 197 ? 216.503 245.349 269.671 1.00 59.10  ? 454 HIS D O   1 
ATOM   3399 C CB  . HIS B 1 197 ? 217.652 243.872 272.503 1.00 48.18  ? 454 HIS D CB  1 
ATOM   3400 C CG  . HIS B 1 197 ? 219.056 243.383 272.333 1.00 53.09  ? 454 HIS D CG  1 
ATOM   3401 N ND1 . HIS B 1 197 ? 220.127 243.949 272.990 1.00 53.77  ? 454 HIS D ND1 1 
ATOM   3402 C CD2 . HIS B 1 197 ? 219.565 242.382 271.577 1.00 52.25  ? 454 HIS D CD2 1 
ATOM   3403 C CE1 . HIS B 1 197 ? 221.235 243.318 272.647 1.00 50.32  ? 454 HIS D CE1 1 
ATOM   3404 N NE2 . HIS B 1 197 ? 220.922 242.362 271.791 1.00 47.71  ? 454 HIS D NE2 1 
ATOM   3405 N N   . THR B 1 198 ? 218.725 245.039 269.884 1.00 42.46  ? 455 THR D N   1 
ATOM   3406 C CA  . THR B 1 198 ? 218.947 244.967 268.441 1.00 47.01  ? 455 THR D CA  1 
ATOM   3407 C C   . THR B 1 198 ? 220.269 244.271 268.170 1.00 47.40  ? 455 THR D C   1 
ATOM   3408 O O   . THR B 1 198 ? 221.323 244.758 268.590 1.00 48.76  ? 455 THR D O   1 
ATOM   3409 C CB  . THR B 1 198 ? 218.939 246.363 267.813 1.00 48.61  ? 455 THR D CB  1 
ATOM   3410 O OG1 . THR B 1 198 ? 217.639 246.947 267.951 1.00 55.32  ? 455 THR D OG1 1 
ATOM   3411 C CG2 . THR B 1 198 ? 219.287 246.282 266.341 1.00 41.46  ? 455 THR D CG2 1 
ATOM   3412 N N   . PHE B 1 199 ? 220.214 243.141 267.471 1.00 54.01  ? 456 PHE D N   1 
ATOM   3413 C CA  . PHE B 1 199 ? 221.417 242.508 266.954 1.00 46.53  ? 456 PHE D CA  1 
ATOM   3414 C C   . PHE B 1 199 ? 221.816 243.191 265.654 1.00 51.14  ? 456 PHE D C   1 
ATOM   3415 O O   . PHE B 1 199 ? 221.023 243.258 264.705 1.00 58.81  ? 456 PHE D O   1 
ATOM   3416 C CB  . PHE B 1 199 ? 221.197 241.015 266.714 1.00 45.96  ? 456 PHE D CB  1 
ATOM   3417 C CG  . PHE B 1 199 ? 220.853 240.238 267.952 1.00 47.62  ? 456 PHE D CG  1 
ATOM   3418 C CD1 . PHE B 1 199 ? 221.842 239.848 268.836 1.00 49.27  ? 456 PHE D CD1 1 
ATOM   3419 C CD2 . PHE B 1 199 ? 219.544 239.881 268.219 1.00 47.74  ? 456 PHE D CD2 1 
ATOM   3420 C CE1 . PHE B 1 199 ? 221.529 239.129 269.968 1.00 52.37  ? 456 PHE D CE1 1 
ATOM   3421 C CE2 . PHE B 1 199 ? 219.226 239.160 269.349 1.00 42.75  ? 456 PHE D CE2 1 
ATOM   3422 C CZ  . PHE B 1 199 ? 220.219 238.785 270.224 1.00 49.92  ? 456 PHE D CZ  1 
ATOM   3423 N N   . LEU B 1 200 ? 223.043 243.698 265.616 1.00 60.29  ? 457 LEU D N   1 
ATOM   3424 C CA  . LEU B 1 200 ? 223.562 244.452 264.488 1.00 60.46  ? 457 LEU D CA  1 
ATOM   3425 C C   . LEU B 1 200 ? 224.519 243.598 263.668 1.00 69.20  ? 457 LEU D C   1 
ATOM   3426 O O   . LEU B 1 200 ? 224.996 242.553 264.119 1.00 74.22  ? 457 LEU D O   1 
ATOM   3427 C CB  . LEU B 1 200 ? 224.292 245.715 264.959 1.00 52.45  ? 457 LEU D CB  1 
ATOM   3428 C CG  . LEU B 1 200 ? 223.642 246.586 266.031 1.00 57.20  ? 457 LEU D CG  1 
ATOM   3429 C CD1 . LEU B 1 200 ? 224.704 247.398 266.745 1.00 59.36  ? 457 LEU D CD1 1 
ATOM   3430 C CD2 . LEU B 1 200 ? 222.602 247.498 265.417 1.00 63.06  ? 457 LEU D CD2 1 
ATOM   3431 N N   . ASP B 1 201 ? 224.764 244.046 262.432 1.00 71.30  ? 458 ASP D N   1 
ATOM   3432 C CA  . ASP B 1 201 ? 225.901 243.598 261.633 1.00 69.18  ? 458 ASP D CA  1 
ATOM   3433 C C   . ASP B 1 201 ? 225.709 242.170 261.124 1.00 71.07  ? 458 ASP D C   1 
ATOM   3434 O O   . ASP B 1 201 ? 226.494 241.689 260.302 1.00 78.51  ? 458 ASP D O   1 
ATOM   3435 C CB  . ASP B 1 201 ? 227.187 243.765 262.466 1.00 75.33  ? 458 ASP D CB  1 
ATOM   3436 C CG  . ASP B 1 201 ? 228.421 243.176 261.809 1.00 76.86  ? 458 ASP D CG  1 
ATOM   3437 O OD1 . ASP B 1 201 ? 228.589 241.939 261.826 1.00 75.34  ? 458 ASP D OD1 1 
ATOM   3438 O OD2 . ASP B 1 201 ? 229.269 243.963 261.341 1.00 76.20  ? 458 ASP D OD2 1 
ATOM   3439 N N   . VAL B 1 202 ? 224.630 241.511 261.554 1.00 64.11  ? 459 VAL D N   1 
ATOM   3440 C CA  . VAL B 1 202 ? 224.437 240.098 261.243 1.00 58.36  ? 459 VAL D CA  1 
ATOM   3441 C C   . VAL B 1 202 ? 224.402 239.890 259.737 1.00 62.94  ? 459 VAL D C   1 
ATOM   3442 O O   . VAL B 1 202 ? 223.699 240.601 259.008 1.00 71.67  ? 459 VAL D O   1 
ATOM   3443 C CB  . VAL B 1 202 ? 223.152 239.576 261.900 1.00 57.88  ? 459 VAL D CB  1 
ATOM   3444 C CG1 . VAL B 1 202 ? 223.158 238.065 261.925 1.00 60.38  ? 459 VAL D CG1 1 
ATOM   3445 C CG2 . VAL B 1 202 ? 223.007 240.135 263.302 1.00 63.90  ? 459 VAL D CG2 1 
ATOM   3446 N N   . SER B 1 203 ? 225.169 238.914 259.264 1.00 58.68  ? 460 SER D N   1 
ATOM   3447 C CA  . SER B 1 203 ? 225.201 238.536 257.857 1.00 64.41  ? 460 SER D CA  1 
ATOM   3448 C C   . SER B 1 203 ? 224.493 237.195 257.717 1.00 61.95  ? 460 SER D C   1 
ATOM   3449 O O   . SER B 1 203 ? 225.040 236.156 258.098 1.00 62.25  ? 460 SER D O   1 
ATOM   3450 C CB  . SER B 1 203 ? 226.635 238.458 257.341 1.00 67.27  ? 460 SER D CB  1 
ATOM   3451 O OG  . SER B 1 203 ? 226.702 237.708 256.142 1.00 68.36  ? 460 SER D OG  1 
ATOM   3452 N N   . PHE B 1 204 ? 223.282 237.220 257.171 1.00 55.87  ? 461 PHE D N   1 
ATOM   3453 C CA  . PHE B 1 204 ? 222.487 236.010 257.069 1.00 61.00  ? 461 PHE D CA  1 
ATOM   3454 C C   . PHE B 1 204 ? 223.074 235.068 256.020 1.00 66.40  ? 461 PHE D C   1 
ATOM   3455 O O   . PHE B 1 204 ? 223.926 235.440 255.209 1.00 65.36  ? 461 PHE D O   1 
ATOM   3456 C CB  . PHE B 1 204 ? 221.038 236.345 256.723 1.00 59.11  ? 461 PHE D CB  1 
ATOM   3457 C CG  . PHE B 1 204 ? 220.349 237.196 257.746 1.00 61.13  ? 461 PHE D CG  1 
ATOM   3458 C CD1 . PHE B 1 204 ? 220.823 237.269 259.043 1.00 59.07  ? 461 PHE D CD1 1 
ATOM   3459 C CD2 . PHE B 1 204 ? 219.223 237.922 257.410 1.00 64.45  ? 461 PHE D CD2 1 
ATOM   3460 C CE1 . PHE B 1 204 ? 220.188 238.053 259.983 1.00 56.57  ? 461 PHE D CE1 1 
ATOM   3461 C CE2 . PHE B 1 204 ? 218.585 238.707 258.348 1.00 65.59  ? 461 PHE D CE2 1 
ATOM   3462 C CZ  . PHE B 1 204 ? 219.069 238.772 259.635 1.00 59.65  ? 461 PHE D CZ  1 
ATOM   3463 N N   . SER B 1 205 ? 222.609 233.822 256.053 1.00 62.09  ? 462 SER D N   1 
ATOM   3464 C CA  . SER B 1 205 ? 223.058 232.795 255.123 1.00 51.48  ? 462 SER D CA  1 
ATOM   3465 C C   . SER B 1 205 ? 221.925 232.225 254.284 1.00 52.63  ? 462 SER D C   1 
ATOM   3466 O O   . SER B 1 205 ? 222.056 232.136 253.058 1.00 58.36  ? 462 SER D O   1 
ATOM   3467 C CB  . SER B 1 205 ? 223.766 231.674 255.897 1.00 59.72  ? 462 SER D CB  1 
ATOM   3468 O OG  . SER B 1 205 ? 222.883 231.059 256.818 1.00 70.24  ? 462 SER D OG  1 
ATOM   3469 N N   . GLU B 1 206 ? 220.816 231.837 254.902 1.00 52.60  ? 463 GLU D N   1 
ATOM   3470 C CA  . GLU B 1 206 ? 219.661 231.311 254.177 1.00 56.74  ? 463 GLU D CA  1 
ATOM   3471 C C   . GLU B 1 206 ? 218.403 231.970 254.734 1.00 60.77  ? 463 GLU D C   1 
ATOM   3472 O O   . GLU B 1 206 ? 218.479 232.958 255.471 1.00 63.42  ? 463 GLU D O   1 
ATOM   3473 C CB  . GLU B 1 206 ? 219.588 229.774 254.253 1.00 60.71  ? 463 GLU D CB  1 
ATOM   3474 C CG  . GLU B 1 206 ? 220.796 229.001 253.738 1.00 65.00  ? 463 GLU D CG  1 
ATOM   3475 C CD  . GLU B 1 206 ? 221.985 229.046 254.666 1.00 69.70  ? 463 GLU D CD  1 
ATOM   3476 O OE1 . GLU B 1 206 ? 223.121 229.177 254.164 1.00 72.44  ? 463 GLU D OE1 1 
ATOM   3477 O OE2 . GLU B 1 206 ? 221.787 228.958 255.895 1.00 73.66  ? 463 GLU D OE2 1 
ATOM   3478 N N   . ALA B 1 207 ? 217.244 231.424 254.371 1.00 56.79  ? 464 ALA D N   1 
ATOM   3479 C CA  . ALA B 1 207 ? 215.970 231.999 254.779 1.00 52.75  ? 464 ALA D CA  1 
ATOM   3480 C C   . ALA B 1 207 ? 215.789 231.907 256.289 1.00 57.55  ? 464 ALA D C   1 
ATOM   3481 O O   . ALA B 1 207 ? 216.334 231.022 256.953 1.00 64.66  ? 464 ALA D O   1 
ATOM   3482 C CB  . ALA B 1 207 ? 214.816 231.291 254.072 1.00 50.98  ? 464 ALA D CB  1 
ATOM   3483 N N   . LEU B 1 208 ? 215.010 232.838 256.830 1.00 57.88  ? 465 LEU D N   1 
ATOM   3484 C CA  . LEU B 1 208 ? 214.811 232.971 258.264 1.00 60.37  ? 465 LEU D CA  1 
ATOM   3485 C C   . LEU B 1 208 ? 213.391 232.573 258.643 1.00 62.49  ? 465 LEU D C   1 
ATOM   3486 O O   . LEU B 1 208 ? 212.458 232.695 257.845 1.00 67.34  ? 465 LEU D O   1 
ATOM   3487 C CB  . LEU B 1 208 ? 215.095 234.404 258.723 1.00 58.94  ? 465 LEU D CB  1 
ATOM   3488 C CG  . LEU B 1 208 ? 216.533 234.915 258.599 1.00 61.97  ? 465 LEU D CG  1 
ATOM   3489 C CD1 . LEU B 1 208 ? 216.852 235.850 259.746 1.00 63.97  ? 465 LEU D CD1 1 
ATOM   3490 C CD2 . LEU B 1 208 ? 217.537 233.774 258.572 1.00 62.94  ? 465 LEU D CD2 1 
ATOM   3491 N N   . TYR B 1 209 ? 213.235 232.101 259.879 1.00 51.83  ? 466 TYR D N   1 
ATOM   3492 C CA  . TYR B 1 209 ? 211.987 231.531 260.349 1.00 48.14  ? 466 TYR D CA  1 
ATOM   3493 C C   . TYR B 1 209 ? 211.639 232.090 261.723 1.00 52.48  ? 466 TYR D C   1 
ATOM   3494 O O   . TYR B 1 209 ? 212.509 232.162 262.595 1.00 52.56  ? 466 TYR D O   1 
ATOM   3495 C CB  . TYR B 1 209 ? 212.106 230.004 260.438 1.00 48.81  ? 466 TYR D CB  1 
ATOM   3496 C CG  . TYR B 1 209 ? 211.357 229.245 259.373 1.00 51.80  ? 466 TYR D CG  1 
ATOM   3497 C CD1 . TYR B 1 209 ? 209.984 229.363 259.241 1.00 53.39  ? 466 TYR D CD1 1 
ATOM   3498 C CD2 . TYR B 1 209 ? 212.025 228.391 258.509 1.00 49.54  ? 466 TYR D CD2 1 
ATOM   3499 C CE1 . TYR B 1 209 ? 209.302 228.664 258.268 1.00 52.27  ? 466 TYR D CE1 1 
ATOM   3500 C CE2 . TYR B 1 209 ? 211.349 227.687 257.538 1.00 47.42  ? 466 TYR D CE2 1 
ATOM   3501 C CZ  . TYR B 1 209 ? 209.988 227.827 257.422 1.00 53.93  ? 466 TYR D CZ  1 
ATOM   3502 O OH  . TYR B 1 209 ? 209.307 227.128 256.454 1.00 61.89  ? 466 TYR D OH  1 
ATOM   3503 N N   . PRO B 1 210 ? 210.388 232.491 261.949 1.00 52.47  ? 467 PRO D N   1 
ATOM   3504 C CA  . PRO B 1 210 ? 209.974 232.864 263.308 1.00 52.25  ? 467 PRO D CA  1 
ATOM   3505 C C   . PRO B 1 210 ? 210.071 231.672 264.249 1.00 56.13  ? 467 PRO D C   1 
ATOM   3506 O O   . PRO B 1 210 ? 209.869 230.525 263.849 1.00 57.86  ? 467 PRO D O   1 
ATOM   3507 C CB  . PRO B 1 210 ? 208.520 233.319 263.128 1.00 44.70  ? 467 PRO D CB  1 
ATOM   3508 C CG  . PRO B 1 210 ? 208.387 233.633 261.675 1.00 41.16  ? 467 PRO D CG  1 
ATOM   3509 C CD  . PRO B 1 210 ? 209.312 232.696 260.966 1.00 49.19  ? 467 PRO D CD  1 
ATOM   3510 N N   . VAL B 1 211 ? 210.388 231.947 265.516 1.00 50.32  ? 468 VAL D N   1 
ATOM   3511 C CA  . VAL B 1 211 ? 210.543 230.888 266.506 1.00 38.03  ? 468 VAL D CA  1 
ATOM   3512 C C   . VAL B 1 211 ? 209.952 231.337 267.836 1.00 41.60  ? 468 VAL D C   1 
ATOM   3513 O O   . VAL B 1 211 ? 209.991 232.518 268.192 1.00 46.58  ? 468 VAL D O   1 
ATOM   3514 C CB  . VAL B 1 211 ? 212.026 230.468 266.662 1.00 36.09  ? 468 VAL D CB  1 
ATOM   3515 C CG1 . VAL B 1 211 ? 212.781 231.426 267.566 1.00 43.88  ? 468 VAL D CG1 1 
ATOM   3516 C CG2 . VAL B 1 211 ? 212.125 229.047 267.183 1.00 43.51  ? 468 VAL D CG2 1 
ATOM   3517 N N   . PHE B 1 212 ? 209.365 230.382 268.556 1.00 47.23  ? 469 PHE D N   1 
ATOM   3518 C CA  . PHE B 1 212 ? 208.806 230.637 269.878 1.00 44.07  ? 469 PHE D CA  1 
ATOM   3519 C C   . PHE B 1 212 ? 209.099 229.447 270.778 1.00 43.23  ? 469 PHE D C   1 
ATOM   3520 O O   . PHE B 1 212 ? 208.952 228.300 270.351 1.00 46.94  ? 469 PHE D O   1 
ATOM   3521 C CB  . PHE B 1 212 ? 207.289 230.865 269.827 1.00 43.26  ? 469 PHE D CB  1 
ATOM   3522 C CG  . PHE B 1 212 ? 206.838 231.777 268.721 1.00 48.64  ? 469 PHE D CG  1 
ATOM   3523 C CD1 . PHE B 1 212 ? 206.639 231.294 267.440 1.00 47.48  ? 469 PHE D CD1 1 
ATOM   3524 C CD2 . PHE B 1 212 ? 206.587 233.112 268.970 1.00 50.05  ? 469 PHE D CD2 1 
ATOM   3525 C CE1 . PHE B 1 212 ? 206.219 232.131 266.428 1.00 50.39  ? 469 PHE D CE1 1 
ATOM   3526 C CE2 . PHE B 1 212 ? 206.166 233.952 267.962 1.00 48.54  ? 469 PHE D CE2 1 
ATOM   3527 C CZ  . PHE B 1 212 ? 205.982 233.461 266.690 1.00 49.65  ? 469 PHE D CZ  1 
ATOM   3528 N N   . ARG B 1 213 ? 209.508 229.714 272.019 1.00 45.13  ? 470 ARG D N   1 
ATOM   3529 C CA  . ARG B 1 213 ? 209.654 228.631 272.992 1.00 43.86  ? 470 ARG D CA  1 
ATOM   3530 C C   . ARG B 1 213 ? 209.196 229.091 274.367 1.00 44.41  ? 470 ARG D C   1 
ATOM   3531 O O   . ARG B 1 213 ? 209.349 230.265 274.716 1.00 60.31  ? 470 ARG D O   1 
ATOM   3532 C CB  . ARG B 1 213 ? 211.091 228.115 273.057 1.00 41.02  ? 470 ARG D CB  1 
ATOM   3533 C CG  . ARG B 1 213 ? 212.153 229.141 272.777 1.00 49.13  ? 470 ARG D CG  1 
ATOM   3534 C CD  . ARG B 1 213 ? 213.476 228.709 273.375 1.00 47.02  ? 470 ARG D CD  1 
ATOM   3535 N NE  . ARG B 1 213 ? 213.512 228.852 274.823 1.00 47.78  ? 470 ARG D NE  1 
ATOM   3536 C CZ  . ARG B 1 213 ? 214.607 228.714 275.557 1.00 46.58  ? 470 ARG D CZ  1 
ATOM   3537 N NH1 . ARG B 1 213 ? 215.766 228.388 275.013 1.00 45.14  ? 470 ARG D NH1 1 
ATOM   3538 N NH2 . ARG B 1 213 ? 214.539 228.919 276.868 1.00 48.52  ? 470 ARG D NH2 1 
ATOM   3539 N N   . ILE B 1 214 ? 208.632 228.161 275.137 1.00 31.22  ? 471 ILE D N   1 
ATOM   3540 C CA  . ILE B 1 214 ? 208.139 228.417 276.487 1.00 50.06  ? 471 ILE D CA  1 
ATOM   3541 C C   . ILE B 1 214 ? 208.412 227.179 277.335 1.00 57.56  ? 471 ILE D C   1 
ATOM   3542 O O   . ILE B 1 214 ? 207.803 226.125 277.116 1.00 59.28  ? 471 ILE D O   1 
ATOM   3543 C CB  . ILE B 1 214 ? 206.646 228.769 276.500 1.00 49.85  ? 471 ILE D CB  1 
ATOM   3544 C CG1 . ILE B 1 214 ? 205.890 227.916 275.485 1.00 41.43  ? 471 ILE D CG1 1 
ATOM   3545 C CG2 . ILE B 1 214 ? 206.444 230.244 276.210 1.00 55.38  ? 471 ILE D CG2 1 
ATOM   3546 C CD1 . ILE B 1 214 ? 204.445 228.274 275.370 1.00 47.27  ? 471 ILE D CD1 1 
ATOM   3547 N N   . LEU B 1 215 ? 209.319 227.302 278.297 1.00 55.33  ? 472 LEU D N   1 
ATOM   3548 C CA  . LEU B 1 215 ? 209.678 226.189 279.179 1.00 48.96  ? 472 LEU D CA  1 
ATOM   3549 C C   . LEU B 1 215 ? 208.849 226.194 280.457 1.00 50.71  ? 472 LEU D C   1 
ATOM   3550 O O   . LEU B 1 215 ? 209.394 226.040 281.548 1.00 56.10  ? 472 LEU D O   1 
ATOM   3551 C CB  . LEU B 1 215 ? 211.163 226.243 279.514 1.00 48.62  ? 472 LEU D CB  1 
ATOM   3552 N N   . THR B 1 216 ? 207.531 226.349 280.351 1.00 55.92  ? 473 THR D N   1 
ATOM   3553 C CA  . THR B 1 216 ? 206.673 226.421 281.530 1.00 58.54  ? 473 THR D CA  1 
ATOM   3554 C C   . THR B 1 216 ? 205.218 226.355 281.091 1.00 57.84  ? 473 THR D C   1 
ATOM   3555 O O   . THR B 1 216 ? 204.897 226.499 279.909 1.00 59.88  ? 473 THR D O   1 
ATOM   3556 C CB  . THR B 1 216 ? 206.926 227.694 282.342 1.00 62.12  ? 473 THR D CB  1 
ATOM   3557 O OG1 . THR B 1 216 ? 205.875 227.869 283.300 1.00 59.56  ? 473 THR D OG1 1 
ATOM   3558 C CG2 . THR B 1 216 ? 206.986 228.901 281.429 1.00 62.92  ? 473 THR D CG2 1 
ATOM   3559 N N   . LEU B 1 217 ? 204.337 226.150 282.070 1.00 55.33  ? 474 LEU D N   1 
ATOM   3560 C CA  . LEU B 1 217 ? 202.897 226.063 281.845 1.00 55.52  ? 474 LEU D CA  1 
ATOM   3561 C C   . LEU B 1 217 ? 202.221 227.201 282.597 1.00 53.22  ? 474 LEU D C   1 
ATOM   3562 O O   . LEU B 1 217 ? 202.369 227.317 283.818 1.00 55.45  ? 474 LEU D O   1 
ATOM   3563 C CB  . LEU B 1 217 ? 202.352 224.708 282.299 1.00 53.30  ? 474 LEU D CB  1 
ATOM   3564 C CG  . LEU B 1 217 ? 200.838 224.490 282.256 1.00 50.38  ? 474 LEU D CG  1 
ATOM   3565 C CD1 . LEU B 1 217 ? 200.529 223.111 281.717 1.00 52.57  ? 474 LEU D CD1 1 
ATOM   3566 C CD2 . LEU B 1 217 ? 200.223 224.661 283.636 1.00 55.05  ? 474 LEU D CD2 1 
ATOM   3567 N N   . GLU B 1 218 ? 201.485 228.033 281.877 1.00 60.57  ? 475 GLU D N   1 
ATOM   3568 C CA  . GLU B 1 218 ? 200.761 229.161 282.439 1.00 61.86  ? 475 GLU D CA  1 
ATOM   3569 C C   . GLU B 1 218 ? 199.398 229.262 281.779 1.00 68.51  ? 475 GLU D C   1 
ATOM   3570 O O   . GLU B 1 218 ? 199.203 228.776 280.660 1.00 74.02  ? 475 GLU D O   1 
ATOM   3571 C CB  . GLU B 1 218 ? 201.533 230.474 282.241 1.00 67.51  ? 475 GLU D CB  1 
ATOM   3572 C CG  . GLU B 1 218 ? 202.622 230.707 283.266 1.00 70.78  ? 475 GLU D CG  1 
ATOM   3573 C CD  . GLU B 1 218 ? 203.945 230.133 282.821 1.00 74.80  ? 475 GLU D CD  1 
ATOM   3574 O OE1 . GLU B 1 218 ? 203.981 229.534 281.727 1.00 78.19  ? 475 GLU D OE1 1 
ATOM   3575 O OE2 . GLU B 1 218 ? 204.943 230.278 283.557 1.00 75.07  ? 475 GLU D OE2 1 
ATOM   3576 N N   . PRO B 1 219 ? 198.425 229.887 282.450 1.00 71.86  ? 476 PRO D N   1 
ATOM   3577 C CA  . PRO B 1 219 ? 197.095 230.043 281.841 1.00 72.44  ? 476 PRO D CA  1 
ATOM   3578 C C   . PRO B 1 219 ? 197.089 230.877 280.571 1.00 73.22  ? 476 PRO D C   1 
ATOM   3579 O O   . PRO B 1 219 ? 196.141 230.757 279.784 1.00 74.78  ? 476 PRO D O   1 
ATOM   3580 C CB  . PRO B 1 219 ? 196.276 230.719 282.950 1.00 70.51  ? 476 PRO D CB  1 
ATOM   3581 C CG  . PRO B 1 219 ? 197.289 231.312 283.875 1.00 68.87  ? 476 PRO D CG  1 
ATOM   3582 C CD  . PRO B 1 219 ? 198.456 230.385 283.834 1.00 68.89  ? 476 PRO D CD  1 
ATOM   3583 N N   . THR B 1 220 ? 198.099 231.711 280.341 1.00 68.30  ? 477 THR D N   1 
ATOM   3584 C CA  . THR B 1 220 ? 198.172 232.552 279.154 1.00 68.62  ? 477 THR D CA  1 
ATOM   3585 C C   . THR B 1 220 ? 199.318 232.087 278.265 1.00 65.90  ? 477 THR D C   1 
ATOM   3586 O O   . THR B 1 220 ? 200.446 231.914 278.737 1.00 62.27  ? 477 THR D O   1 
ATOM   3587 C CB  . THR B 1 220 ? 198.358 234.022 279.535 1.00 72.69  ? 477 THR D CB  1 
ATOM   3588 O OG1 . THR B 1 220 ? 199.748 234.290 279.746 1.00 75.47  ? 477 THR D OG1 1 
ATOM   3589 C CG2 . THR B 1 220 ? 197.588 234.344 280.805 1.00 69.42  ? 477 THR D CG2 1 
ATOM   3590 N N   . ALA B 1 221 ? 199.021 231.876 276.987 1.00 69.44  ? 478 ALA D N   1 
ATOM   3591 C CA  . ALA B 1 221 ? 199.995 231.386 276.024 1.00 71.37  ? 478 ALA D CA  1 
ATOM   3592 C C   . ALA B 1 221 ? 200.664 232.557 275.301 1.00 69.75  ? 478 ALA D C   1 
ATOM   3593 O O   . ALA B 1 221 ? 200.537 233.719 275.696 1.00 72.85  ? 478 ALA D O   1 
ATOM   3594 C CB  . ALA B 1 221 ? 199.324 230.426 275.044 1.00 74.93  ? 478 ALA D CB  1 
ATOM   3595 N N   . LEU B 1 222 ? 201.395 232.252 274.233 1.00 57.90  ? 479 LEU D N   1 
ATOM   3596 C CA  . LEU B 1 222 ? 202.036 233.249 273.377 1.00 57.48  ? 479 LEU D CA  1 
ATOM   3597 C C   . LEU B 1 222 ? 201.103 233.544 272.205 1.00 60.49  ? 479 LEU D C   1 
ATOM   3598 O O   . LEU B 1 222 ? 201.070 232.808 271.218 1.00 65.19  ? 479 LEU D O   1 
ATOM   3599 C CB  . LEU B 1 222 ? 203.395 232.759 272.887 1.00 59.47  ? 479 LEU D CB  1 
ATOM   3600 C CG  . LEU B 1 222 ? 204.630 233.437 273.475 1.00 61.74  ? 479 LEU D CG  1 
ATOM   3601 C CD1 . LEU B 1 222 ? 204.686 233.220 274.967 1.00 63.85  ? 479 LEU D CD1 1 
ATOM   3602 C CD2 . LEU B 1 222 ? 205.890 232.914 272.812 1.00 58.62  ? 479 LEU D CD2 1 
ATOM   3603 N N   . THR B 1 223 ? 200.345 234.628 272.319 1.00 58.50  ? 480 THR D N   1 
ATOM   3604 C CA  . THR B 1 223 ? 199.473 235.054 271.236 1.00 54.00  ? 480 THR D CA  1 
ATOM   3605 C C   . THR B 1 223 ? 200.256 235.865 270.211 1.00 55.83  ? 480 THR D C   1 
ATOM   3606 O O   . THR B 1 223 ? 201.190 236.597 270.549 1.00 64.85  ? 480 THR D O   1 
ATOM   3607 C CB  . THR B 1 223 ? 198.309 235.885 271.775 1.00 58.77  ? 480 THR D CB  1 
ATOM   3608 O OG1 . THR B 1 223 ? 197.914 235.380 273.055 1.00 63.69  ? 480 THR D OG1 1 
ATOM   3609 C CG2 . THR B 1 223 ? 197.125 235.820 270.828 1.00 55.73  ? 480 THR D CG2 1 
ATOM   3610 N N   . ILE B 1 224 ? 199.868 235.727 268.948 1.00 54.74  ? 481 ILE D N   1 
ATOM   3611 C CA  . ILE B 1 224 ? 200.521 236.417 267.841 1.00 58.36  ? 481 ILE D CA  1 
ATOM   3612 C C   . ILE B 1 224 ? 199.505 237.351 267.205 1.00 56.16  ? 481 ILE D C   1 
ATOM   3613 O O   . ILE B 1 224 ? 198.444 236.907 266.749 1.00 59.41  ? 481 ILE D O   1 
ATOM   3614 C CB  . ILE B 1 224 ? 201.087 235.433 266.807 1.00 58.58  ? 481 ILE D CB  1 
ATOM   3615 C CG1 . ILE B 1 224 ? 202.382 234.809 267.323 1.00 58.08  ? 481 ILE D CG1 1 
ATOM   3616 C CG2 . ILE B 1 224 ? 201.340 236.135 265.487 1.00 58.03  ? 481 ILE D CG2 1 
ATOM   3617 C CD1 . ILE B 1 224 ? 202.501 233.336 267.027 1.00 58.08  ? 481 ILE D CD1 1 
ATOM   3618 N N   . CYS B 1 225 ? 199.824 238.640 267.182 1.00 68.91  ? 482 CYS D N   1 
ATOM   3619 C CA  . CYS B 1 225 ? 198.937 239.613 266.574 1.00 71.80  ? 482 CYS D CA  1 
ATOM   3620 C C   . CYS B 1 225 ? 199.015 239.518 265.051 1.00 80.71  ? 482 CYS D C   1 
ATOM   3621 O O   . CYS B 1 225 ? 200.049 239.138 264.497 1.00 83.46  ? 482 CYS D O   1 
ATOM   3622 C CB  . CYS B 1 225 ? 199.299 241.023 267.030 1.00 78.56  ? 482 CYS D CB  1 
ATOM   3623 S SG  . CYS B 1 225 ? 198.266 241.651 268.370 1.00 91.66  ? 482 CYS D SG  1 
ATOM   3624 N N   . PRO B 1 226 ? 197.929 239.859 264.350 1.00 100.19 ? 483 PRO D N   1 
ATOM   3625 C CA  . PRO B 1 226 ? 197.945 239.778 262.882 1.00 98.30  ? 483 PRO D CA  1 
ATOM   3626 C C   . PRO B 1 226 ? 198.868 240.806 262.248 1.00 98.61  ? 483 PRO D C   1 
ATOM   3627 O O   . PRO B 1 226 ? 199.516 241.590 262.948 1.00 102.13 ? 483 PRO D O   1 
ATOM   3628 C CB  . PRO B 1 226 ? 196.480 240.032 262.497 1.00 96.46  ? 483 PRO D CB  1 
ATOM   3629 C CG  . PRO B 1 226 ? 195.694 239.832 263.756 1.00 96.36  ? 483 PRO D CG  1 
ATOM   3630 C CD  . PRO B 1 226 ? 196.603 240.231 264.868 1.00 96.83  ? 483 PRO D CD  1 
ATOM   3631 N N   . ALA B 1 227 ? 198.935 240.806 260.921 1.00 102.22 ? 484 ALA D N   1 
ATOM   3632 C CA  . ALA B 1 227 ? 199.772 241.753 260.192 1.00 104.31 ? 484 ALA D CA  1 
ATOM   3633 C C   . ALA B 1 227 ? 199.285 243.184 260.391 1.00 103.31 ? 484 ALA D C   1 
ATOM   3634 O O   . ALA B 1 227 ? 199.872 243.948 261.158 1.00 104.64 ? 484 ALA D O   1 
ATOM   3635 C CB  . ALA B 1 227 ? 199.798 241.405 258.712 1.00 102.03 ? 484 ALA D CB  1 
ATOM   3636 N N   . TRP C 2 1   ? 222.070 198.828 195.616 1.00 132.26 ? 240 TRP G N   1 
ATOM   3637 C CA  . TRP C 2 1   ? 220.988 198.651 194.655 1.00 132.46 ? 240 TRP G CA  1 
ATOM   3638 C C   . TRP C 2 1   ? 219.713 198.169 195.340 1.00 133.10 ? 240 TRP G C   1 
ATOM   3639 O O   . TRP C 2 1   ? 219.595 198.226 196.563 1.00 134.14 ? 240 TRP G O   1 
ATOM   3640 C CB  . TRP C 2 1   ? 221.401 197.664 193.561 1.00 131.04 ? 240 TRP G CB  1 
ATOM   3641 N N   . ILE C 2 2   ? 218.758 197.698 194.535 1.00 135.59 ? 241 ILE G N   1 
ATOM   3642 C CA  . ILE C 2 2   ? 217.499 197.200 195.083 1.00 136.23 ? 241 ILE G CA  1 
ATOM   3643 C C   . ILE C 2 2   ? 217.742 195.975 195.956 1.00 137.11 ? 241 ILE G C   1 
ATOM   3644 O O   . ILE C 2 2   ? 217.171 195.849 197.047 1.00 137.28 ? 241 ILE G O   1 
ATOM   3645 C CB  . ILE C 2 2   ? 216.501 196.908 193.944 1.00 136.21 ? 241 ILE G CB  1 
ATOM   3646 C CG1 . ILE C 2 2   ? 215.217 196.278 194.490 1.00 135.60 ? 241 ILE G CG1 1 
ATOM   3647 C CG2 . ILE C 2 2   ? 217.139 196.035 192.864 1.00 134.25 ? 241 ILE G CG2 1 
ATOM   3648 C CD1 . ILE C 2 2   ? 214.200 197.279 194.993 1.00 133.47 ? 241 ILE G CD1 1 
ATOM   3649 N N   . ASN C 2 3   ? 218.600 195.060 195.497 1.00 137.33 ? 242 ASN G N   1 
ATOM   3650 C CA  . ASN C 2 3   ? 218.910 193.867 196.279 1.00 137.38 ? 242 ASN G CA  1 
ATOM   3651 C C   . ASN C 2 3   ? 219.578 194.236 197.597 1.00 137.85 ? 242 ASN G C   1 
ATOM   3652 O O   . ASN C 2 3   ? 219.233 193.698 198.660 1.00 136.89 ? 242 ASN G O   1 
ATOM   3653 C CB  . ASN C 2 3   ? 219.805 192.931 195.467 1.00 136.30 ? 242 ASN G CB  1 
ATOM   3654 C CG  . ASN C 2 3   ? 220.883 193.675 194.703 1.00 136.19 ? 242 ASN G CG  1 
ATOM   3655 O OD1 . ASN C 2 3   ? 221.758 194.304 195.298 1.00 136.61 ? 242 ASN G OD1 1 
ATOM   3656 N ND2 . ASN C 2 3   ? 220.827 193.603 193.379 1.00 133.21 ? 242 ASN G ND2 1 
ATOM   3657 N N   . LYS C 2 4   ? 220.548 195.150 197.544 1.00 137.70 ? 243 LYS G N   1 
ATOM   3658 C CA  . LYS C 2 4   ? 221.220 195.583 198.762 1.00 138.53 ? 243 LYS G CA  1 
ATOM   3659 C C   . LYS C 2 4   ? 220.200 196.144 199.739 1.00 136.99 ? 243 LYS G C   1 
ATOM   3660 O O   . LYS C 2 4   ? 220.256 195.871 200.942 1.00 136.61 ? 243 LYS G O   1 
ATOM   3661 C CB  . LYS C 2 4   ? 222.277 196.636 198.420 1.00 137.83 ? 243 LYS G CB  1 
ATOM   3662 C CG  . LYS C 2 4   ? 222.984 197.309 199.597 1.00 137.41 ? 243 LYS G CG  1 
ATOM   3663 C CD  . LYS C 2 4   ? 223.585 196.293 200.568 1.00 138.26 ? 243 LYS G CD  1 
ATOM   3664 C CE  . LYS C 2 4   ? 223.222 196.550 202.020 1.00 137.62 ? 243 LYS G CE  1 
ATOM   3665 N NZ  . LYS C 2 4   ? 221.872 196.056 202.365 1.00 136.71 ? 243 LYS G NZ  1 
ATOM   3666 N N   . LEU C 2 5   ? 219.216 196.880 199.220 1.00 131.51 ? 244 LEU G N   1 
ATOM   3667 C CA  . LEU C 2 5   ? 218.213 197.502 200.074 1.00 130.73 ? 244 LEU G CA  1 
ATOM   3668 C C   . LEU C 2 5   ? 217.258 196.474 200.674 1.00 129.89 ? 244 LEU G C   1 
ATOM   3669 O O   . LEU C 2 5   ? 216.841 196.615 201.829 1.00 131.71 ? 244 LEU G O   1 
ATOM   3670 C CB  . LEU C 2 5   ? 217.457 198.568 199.284 1.00 133.50 ? 244 LEU G CB  1 
ATOM   3671 C CG  . LEU C 2 5   ? 218.234 199.885 199.196 1.00 133.13 ? 244 LEU G CG  1 
ATOM   3672 C CD1 . LEU C 2 5   ? 217.562 200.894 198.278 1.00 131.33 ? 244 LEU G CD1 1 
ATOM   3673 C CD2 . LEU C 2 5   ? 218.418 200.471 200.588 1.00 130.53 ? 244 LEU G CD2 1 
ATOM   3674 N N   . GLN C 2 6   ? 216.884 195.438 199.914 1.00 129.09 ? 245 GLN G N   1 
ATOM   3675 C CA  . GLN C 2 6   ? 216.004 194.434 200.510 1.00 130.41 ? 245 GLN G CA  1 
ATOM   3676 C C   . GLN C 2 6   ? 216.729 193.644 201.593 1.00 130.44 ? 245 GLN G C   1 
ATOM   3677 O O   . GLN C 2 6   ? 216.150 193.363 202.652 1.00 129.58 ? 245 GLN G O   1 
ATOM   3678 C CB  . GLN C 2 6   ? 215.407 193.482 199.467 1.00 131.63 ? 245 GLN G CB  1 
ATOM   3679 C CG  . GLN C 2 6   ? 216.327 192.985 198.387 1.00 132.48 ? 245 GLN G CG  1 
ATOM   3680 C CD  . GLN C 2 6   ? 215.622 192.802 197.057 1.00 131.36 ? 245 GLN G CD  1 
ATOM   3681 O OE1 . GLN C 2 6   ? 215.553 193.719 196.244 1.00 130.28 ? 245 GLN G OE1 1 
ATOM   3682 N NE2 . GLN C 2 6   ? 215.102 191.602 196.826 1.00 131.06 ? 245 GLN G NE2 1 
ATOM   3683 N N   . LYS C 2 7   ? 217.999 193.281 201.366 1.00 128.22 ? 246 LYS G N   1 
ATOM   3684 C CA  . LYS C 2 7   ? 218.727 192.644 202.464 1.00 128.28 ? 246 LYS G CA  1 
ATOM   3685 C C   . LYS C 2 7   ? 218.891 193.594 203.646 1.00 130.22 ? 246 LYS G C   1 
ATOM   3686 O O   . LYS C 2 7   ? 218.860 193.156 204.801 1.00 128.85 ? 246 LYS G O   1 
ATOM   3687 C CB  . LYS C 2 7   ? 220.089 192.075 202.040 1.00 128.61 ? 246 LYS G CB  1 
ATOM   3688 C CG  . LYS C 2 7   ? 220.294 191.615 200.605 1.00 128.22 ? 246 LYS G CG  1 
ATOM   3689 C CD  . LYS C 2 7   ? 221.689 191.995 200.113 1.00 129.97 ? 246 LYS G CD  1 
ATOM   3690 C CE  . LYS C 2 7   ? 221.793 192.025 198.598 1.00 130.54 ? 246 LYS G CE  1 
ATOM   3691 N NZ  . LYS C 2 7   ? 222.981 192.794 198.139 1.00 130.45 ? 246 LYS G NZ  1 
ATOM   3692 N N   . GLU C 2 8   ? 219.065 194.895 203.382 1.00 129.67 ? 247 GLU G N   1 
ATOM   3693 C CA  . GLU C 2 8   ? 219.138 195.868 204.470 1.00 127.83 ? 247 GLU G CA  1 
ATOM   3694 C C   . GLU C 2 8   ? 217.860 195.876 205.296 1.00 126.38 ? 247 GLU G C   1 
ATOM   3695 O O   . GLU C 2 8   ? 217.907 195.905 206.531 1.00 125.36 ? 247 GLU G O   1 
ATOM   3696 C CB  . GLU C 2 8   ? 219.407 197.265 203.911 1.00 130.08 ? 247 GLU G CB  1 
ATOM   3697 C CG  . GLU C 2 8   ? 219.513 198.354 204.969 1.00 129.83 ? 247 GLU G CG  1 
ATOM   3698 C CD  . GLU C 2 8   ? 218.221 199.131 205.138 1.00 128.66 ? 247 GLU G CD  1 
ATOM   3699 O OE1 . GLU C 2 8   ? 218.213 200.116 205.905 1.00 126.36 ? 247 GLU G OE1 1 
ATOM   3700 O OE2 . GLU C 2 8   ? 217.211 198.760 204.504 1.00 129.59 ? 247 GLU G OE2 1 
ATOM   3701 N N   . LYS C 2 9   ? 216.707 195.872 204.628 1.00 115.98 ? 248 LYS G N   1 
ATOM   3702 C CA  . LYS C 2 9   ? 215.439 195.810 205.345 1.00 114.00 ? 248 LYS G CA  1 
ATOM   3703 C C   . LYS C 2 9   ? 215.346 194.528 206.157 1.00 114.59 ? 248 LYS G C   1 
ATOM   3704 O O   . LYS C 2 9   ? 214.918 194.543 207.318 1.00 113.86 ? 248 LYS G O   1 
ATOM   3705 C CB  . LYS C 2 9   ? 214.272 195.915 204.363 1.00 114.00 ? 248 LYS G CB  1 
ATOM   3706 N N   . LYS C 2 10  ? 215.774 193.409 205.567 1.00 112.79 ? 249 LYS G N   1 
ATOM   3707 C CA  . LYS C 2 10  ? 215.714 192.130 206.266 1.00 110.34 ? 249 LYS G CA  1 
ATOM   3708 C C   . LYS C 2 10  ? 216.559 192.142 207.535 1.00 110.82 ? 249 LYS G C   1 
ATOM   3709 O O   . LYS C 2 10  ? 216.115 191.655 208.581 1.00 109.33 ? 249 LYS G O   1 
ATOM   3710 C CB  . LYS C 2 10  ? 216.164 191.005 205.334 1.00 110.34 ? 249 LYS G CB  1 
ATOM   3711 N N   . ILE C 2 11  ? 217.776 192.691 207.472 1.00 117.25 ? 250 ILE G N   1 
ATOM   3712 C CA  . ILE C 2 11  ? 218.641 192.642 208.650 1.00 117.25 ? 250 ILE G CA  1 
ATOM   3713 C C   . ILE C 2 11  ? 218.185 193.657 209.689 1.00 115.07 ? 250 ILE G C   1 
ATOM   3714 O O   . ILE C 2 11  ? 218.055 193.332 210.875 1.00 112.86 ? 250 ILE G O   1 
ATOM   3715 C CB  . ILE C 2 11  ? 220.122 192.859 208.283 1.00 118.58 ? 250 ILE G CB  1 
ATOM   3716 C CG1 . ILE C 2 11  ? 220.283 193.948 207.227 1.00 118.01 ? 250 ILE G CG1 1 
ATOM   3717 C CG2 . ILE C 2 11  ? 220.745 191.555 207.804 1.00 116.36 ? 250 ILE G CG2 1 
ATOM   3718 C CD1 . ILE C 2 11  ? 221.697 194.107 206.711 1.00 115.77 ? 250 ILE G CD1 1 
ATOM   3719 N N   . LEU C 2 12  ? 217.937 194.900 209.271 1.00 109.77 ? 251 LEU G N   1 
ATOM   3720 C CA  . LEU C 2 12  ? 217.609 195.952 210.220 1.00 109.51 ? 251 LEU G CA  1 
ATOM   3721 C C   . LEU C 2 12  ? 216.212 195.814 210.802 1.00 108.95 ? 251 LEU G C   1 
ATOM   3722 O O   . LEU C 2 12  ? 215.927 196.424 211.838 1.00 107.52 ? 251 LEU G O   1 
ATOM   3723 C CB  . LEU C 2 12  ? 217.759 197.326 209.561 1.00 111.28 ? 251 LEU G CB  1 
ATOM   3724 C CG  . LEU C 2 12  ? 218.501 198.357 210.412 1.00 109.91 ? 251 LEU G CG  1 
ATOM   3725 C CD1 . LEU C 2 12  ? 219.762 197.754 211.011 1.00 109.48 ? 251 LEU G CD1 1 
ATOM   3726 C CD2 . LEU C 2 12  ? 218.833 199.591 209.590 1.00 110.75 ? 251 LEU G CD2 1 
ATOM   3727 N N   . SER C 2 13  ? 215.336 195.031 210.170 1.00 115.32 ? 252 SER G N   1 
ATOM   3728 C CA  . SER C 2 13  ? 214.078 194.684 210.821 1.00 116.02 ? 252 SER G CA  1 
ATOM   3729 C C   . SER C 2 13  ? 214.285 193.566 211.834 1.00 117.45 ? 252 SER G C   1 
ATOM   3730 O O   . SER C 2 13  ? 213.389 193.268 212.631 1.00 117.79 ? 252 SER G O   1 
ATOM   3731 C CB  . SER C 2 13  ? 213.038 194.283 209.777 1.00 115.90 ? 252 SER G CB  1 
ATOM   3732 O OG  . SER C 2 13  ? 211.886 193.734 210.393 1.00 116.57 ? 252 SER G OG  1 
ATOM   3733 N N   . GLY C 2 14  ? 215.461 192.943 211.818 1.00 115.10 ? 253 GLY G N   1 
ATOM   3734 C CA  . GLY C 2 14  ? 215.774 191.853 212.717 1.00 113.02 ? 253 GLY G CA  1 
ATOM   3735 C C   . GLY C 2 14  ? 216.366 192.313 214.032 1.00 115.40 ? 253 GLY G C   1 
ATOM   3736 O O   . GLY C 2 14  ? 216.898 191.504 214.797 1.00 116.40 ? 253 GLY G O   1 
ATOM   3737 N N   . GLU C 2 15  ? 216.302 193.616 214.296 1.00 122.27 ? 254 GLU G N   1 
ATOM   3738 C CA  . GLU C 2 15  ? 216.784 194.166 215.560 1.00 121.59 ? 254 GLU G CA  1 
ATOM   3739 C C   . GLU C 2 15  ? 215.683 194.487 216.562 1.00 121.39 ? 254 GLU G C   1 
ATOM   3740 O O   . GLU C 2 15  ? 216.002 194.809 217.711 1.00 122.03 ? 254 GLU G O   1 
ATOM   3741 C CB  . GLU C 2 15  ? 217.609 195.434 215.302 1.00 120.45 ? 254 GLU G CB  1 
ATOM   3742 C CG  . GLU C 2 15  ? 218.638 195.737 216.375 1.00 124.74 ? 254 GLU G CG  1 
ATOM   3743 C CD  . GLU C 2 15  ? 219.656 194.626 216.530 1.00 126.98 ? 254 GLU G CD  1 
ATOM   3744 O OE1 . GLU C 2 15  ? 220.473 194.433 215.605 1.00 126.67 ? 254 GLU G OE1 1 
ATOM   3745 O OE2 . GLU C 2 15  ? 219.638 193.944 217.575 1.00 127.01 ? 254 GLU G OE2 1 
ATOM   3746 N N   . LYS C 2 16  ? 214.405 194.404 216.187 1.00 122.96 ? 255 LYS G N   1 
ATOM   3747 C CA  . LYS C 2 16  ? 213.332 194.804 217.092 1.00 124.64 ? 255 LYS G CA  1 
ATOM   3748 C C   . LYS C 2 16  ? 213.174 193.819 218.245 1.00 125.76 ? 255 LYS G C   1 
ATOM   3749 O O   . LYS C 2 16  ? 212.935 194.221 219.390 1.00 126.62 ? 255 LYS G O   1 
ATOM   3750 C CB  . LYS C 2 16  ? 212.020 194.936 216.317 1.00 123.16 ? 255 LYS G CB  1 
ATOM   3751 C CG  . LYS C 2 16  ? 210.983 195.819 216.992 1.00 123.90 ? 255 LYS G CG  1 
ATOM   3752 C CD  . LYS C 2 16  ? 211.347 197.291 216.903 1.00 125.59 ? 255 LYS G CD  1 
ATOM   3753 C CE  . LYS C 2 16  ? 211.702 197.695 215.483 1.00 125.18 ? 255 LYS G CE  1 
ATOM   3754 N NZ  . LYS C 2 16  ? 212.193 199.100 215.417 1.00 122.15 ? 255 LYS G NZ  1 
ATOM   3755 N N   . GLU C 2 17  ? 213.294 192.520 217.959 1.00 129.15 ? 256 GLU G N   1 
ATOM   3756 C CA  . GLU C 2 17  ? 212.982 191.506 218.964 1.00 130.74 ? 256 GLU G CA  1 
ATOM   3757 C C   . GLU C 2 17  ? 213.931 191.586 220.156 1.00 130.13 ? 256 GLU G C   1 
ATOM   3758 O O   . GLU C 2 17  ? 213.504 191.438 221.308 1.00 126.38 ? 256 GLU G O   1 
ATOM   3759 C CB  . GLU C 2 17  ? 213.008 190.112 218.325 1.00 130.75 ? 256 GLU G CB  1 
ATOM   3760 C CG  . GLU C 2 17  ? 214.385 189.455 218.150 1.00 131.31 ? 256 GLU G CG  1 
ATOM   3761 C CD  . GLU C 2 17  ? 215.316 190.183 217.184 1.00 130.55 ? 256 GLU G CD  1 
ATOM   3762 O OE1 . GLU C 2 17  ? 215.109 191.381 216.896 1.00 128.22 ? 256 GLU G OE1 1 
ATOM   3763 O OE2 . GLU C 2 17  ? 216.277 189.542 216.710 1.00 130.99 ? 256 GLU G OE2 1 
ATOM   3764 N N   . PHE C 2 18  ? 215.221 191.821 219.902 1.00 131.01 ? 257 PHE G N   1 
ATOM   3765 C CA  . PHE C 2 18  ? 216.181 191.954 220.992 1.00 129.44 ? 257 PHE G CA  1 
ATOM   3766 C C   . PHE C 2 18  ? 215.865 193.162 221.863 1.00 130.52 ? 257 PHE G C   1 
ATOM   3767 O O   . PHE C 2 18  ? 215.943 193.081 223.098 1.00 130.31 ? 257 PHE G O   1 
ATOM   3768 C CB  . PHE C 2 18  ? 217.595 192.041 220.418 1.00 128.71 ? 257 PHE G CB  1 
ATOM   3769 C CG  . PHE C 2 18  ? 218.566 192.774 221.293 1.00 131.36 ? 257 PHE G CG  1 
ATOM   3770 C CD1 . PHE C 2 18  ? 219.168 192.138 222.364 1.00 132.45 ? 257 PHE G CD1 1 
ATOM   3771 C CD2 . PHE C 2 18  ? 218.890 194.095 221.035 1.00 129.97 ? 257 PHE G CD2 1 
ATOM   3772 C CE1 . PHE C 2 18  ? 220.069 192.807 223.167 1.00 132.80 ? 257 PHE G CE1 1 
ATOM   3773 C CE2 . PHE C 2 18  ? 219.787 194.768 221.835 1.00 131.01 ? 257 PHE G CE2 1 
ATOM   3774 C CZ  . PHE C 2 18  ? 220.378 194.125 222.903 1.00 132.64 ? 257 PHE G CZ  1 
ATOM   3775 N N   . GLU C 2 19  ? 215.496 194.281 221.239 1.00 123.55 ? 258 GLU G N   1 
ATOM   3776 C CA  . GLU C 2 19  ? 215.044 195.435 222.001 1.00 122.98 ? 258 GLU G CA  1 
ATOM   3777 C C   . GLU C 2 19  ? 213.814 195.106 222.834 1.00 125.54 ? 258 GLU G C   1 
ATOM   3778 O O   . GLU C 2 19  ? 213.696 195.573 223.971 1.00 125.71 ? 258 GLU G O   1 
ATOM   3779 C CB  . GLU C 2 19  ? 214.755 196.603 221.061 1.00 121.20 ? 258 GLU G CB  1 
ATOM   3780 C CG  . GLU C 2 19  ? 214.293 197.884 221.746 1.00 125.39 ? 258 GLU G CG  1 
ATOM   3781 C CD  . GLU C 2 19  ? 215.254 198.391 222.812 1.00 128.54 ? 258 GLU G CD  1 
ATOM   3782 O OE1 . GLU C 2 19  ? 215.910 199.423 222.565 1.00 125.39 ? 258 GLU G OE1 1 
ATOM   3783 O OE2 . GLU C 2 19  ? 215.335 197.792 223.906 1.00 129.07 ? 258 GLU G OE2 1 
ATOM   3784 N N   . ARG C 2 20  ? 212.897 194.301 222.293 1.00 128.68 ? 259 ARG G N   1 
ATOM   3785 C CA  . ARG C 2 20  ? 211.697 193.940 223.041 1.00 128.85 ? 259 ARG G CA  1 
ATOM   3786 C C   . ARG C 2 20  ? 212.039 193.162 224.308 1.00 127.48 ? 259 ARG G C   1 
ATOM   3787 O O   . ARG C 2 20  ? 211.528 193.476 225.391 1.00 128.63 ? 259 ARG G O   1 
ATOM   3788 C CB  . ARG C 2 20  ? 210.751 193.132 222.153 1.00 128.00 ? 259 ARG G CB  1 
ATOM   3789 C CG  . ARG C 2 20  ? 210.126 193.905 220.989 1.00 128.75 ? 259 ARG G CG  1 
ATOM   3790 C CD  . ARG C 2 20  ? 209.129 194.986 221.431 1.00 127.98 ? 259 ARG G CD  1 
ATOM   3791 N NE  . ARG C 2 20  ? 209.733 196.143 222.084 1.00 128.43 ? 259 ARG G NE  1 
ATOM   3792 C CZ  . ARG C 2 20  ? 210.553 197.005 221.498 1.00 127.69 ? 259 ARG G CZ  1 
ATOM   3793 N NH1 . ARG C 2 20  ? 210.894 196.883 220.225 1.00 127.88 ? 259 ARG G NH1 1 
ATOM   3794 N NH2 . ARG C 2 20  ? 211.038 198.022 222.204 1.00 126.82 ? 259 ARG G NH2 1 
ATOM   3795 N N   . GLU C 2 21  ? 212.904 192.151 224.200 1.00 129.08 ? 260 GLU G N   1 
ATOM   3796 C CA  . GLU C 2 21  ? 213.255 191.382 225.388 1.00 132.18 ? 260 GLU G CA  1 
ATOM   3797 C C   . GLU C 2 21  ? 214.073 192.198 226.377 1.00 130.70 ? 260 GLU G C   1 
ATOM   3798 O O   . GLU C 2 21  ? 213.906 192.018 227.589 1.00 128.88 ? 260 GLU G O   1 
ATOM   3799 C CB  . GLU C 2 21  ? 214.005 190.101 225.012 1.00 132.87 ? 260 GLU G CB  1 
ATOM   3800 C CG  . GLU C 2 21  ? 215.054 190.261 223.935 1.00 133.00 ? 260 GLU G CG  1 
ATOM   3801 C CD  . GLU C 2 21  ? 215.245 188.999 223.117 1.00 134.80 ? 260 GLU G CD  1 
ATOM   3802 O OE1 . GLU C 2 21  ? 215.731 187.994 223.678 1.00 134.48 ? 260 GLU G OE1 1 
ATOM   3803 O OE2 . GLU C 2 21  ? 214.911 189.010 221.914 1.00 134.50 ? 260 GLU G OE2 1 
ATOM   3804 N N   . THR C 2 22  ? 214.943 193.095 225.899 1.00 120.34 ? 261 THR G N   1 
ATOM   3805 C CA  . THR C 2 22  ? 215.631 193.985 226.829 1.00 121.19 ? 261 THR G CA  1 
ATOM   3806 C C   . THR C 2 22  ? 214.650 194.889 227.567 1.00 120.95 ? 261 THR G C   1 
ATOM   3807 O O   . THR C 2 22  ? 214.773 195.076 228.785 1.00 119.86 ? 261 THR G O   1 
ATOM   3808 C CB  . THR C 2 22  ? 216.675 194.824 226.094 1.00 121.39 ? 261 THR G CB  1 
ATOM   3809 O OG1 . THR C 2 22  ? 216.054 195.512 225.002 1.00 122.42 ? 261 THR G OG1 1 
ATOM   3810 C CG2 . THR C 2 22  ? 217.794 193.942 225.571 1.00 121.42 ? 261 THR G CG2 1 
ATOM   3811 N N   . ARG C 2 23  ? 213.664 195.442 226.856 1.00 115.00 ? 262 ARG G N   1 
ATOM   3812 C CA  . ARG C 2 23  ? 212.629 196.230 227.516 1.00 113.20 ? 262 ARG G CA  1 
ATOM   3813 C C   . ARG C 2 23  ? 211.915 195.407 228.578 1.00 115.01 ? 262 ARG G C   1 
ATOM   3814 O O   . ARG C 2 23  ? 211.694 195.880 229.699 1.00 117.65 ? 262 ARG G O   1 
ATOM   3815 C CB  . ARG C 2 23  ? 211.624 196.743 226.485 1.00 113.20 ? 262 ARG G CB  1 
ATOM   3816 C CG  . ARG C 2 23  ? 212.140 197.839 225.568 1.00 116.52 ? 262 ARG G CG  1 
ATOM   3817 C CD  . ARG C 2 23  ? 211.963 199.221 226.174 1.00 116.57 ? 262 ARG G CD  1 
ATOM   3818 N NE  . ARG C 2 23  ? 213.215 199.750 226.699 1.00 115.86 ? 262 ARG G NE  1 
ATOM   3819 C CZ  . ARG C 2 23  ? 213.401 201.009 227.069 1.00 116.48 ? 262 ARG G CZ  1 
ATOM   3820 N NH1 . ARG C 2 23  ? 212.433 201.906 226.979 1.00 117.21 ? 262 ARG G NH1 1 
ATOM   3821 N NH2 . ARG C 2 23  ? 214.588 201.378 227.539 1.00 113.92 ? 262 ARG G NH2 1 
ATOM   3822 N N   . GLU C 2 24  ? 211.553 194.167 228.241 1.00 115.50 ? 263 GLU G N   1 
ATOM   3823 C CA  . GLU C 2 24  ? 210.821 193.329 229.185 1.00 114.24 ? 263 GLU G CA  1 
ATOM   3824 C C   . GLU C 2 24  ? 211.644 193.037 230.433 1.00 113.37 ? 263 GLU G C   1 
ATOM   3825 O O   . GLU C 2 24  ? 211.127 193.116 231.557 1.00 115.10 ? 263 GLU G O   1 
ATOM   3826 C CB  . GLU C 2 24  ? 210.394 192.028 228.509 1.00 114.17 ? 263 GLU G CB  1 
ATOM   3827 C CG  . GLU C 2 24  ? 209.357 192.219 227.419 1.00 118.32 ? 263 GLU G CG  1 
ATOM   3828 C CD  . GLU C 2 24  ? 208.316 193.255 227.791 1.00 119.70 ? 263 GLU G CD  1 
ATOM   3829 O OE1 . GLU C 2 24  ? 207.551 193.014 228.748 1.00 119.21 ? 263 GLU G OE1 1 
ATOM   3830 O OE2 . GLU C 2 24  ? 208.265 194.313 227.129 1.00 118.47 ? 263 GLU G OE2 1 
ATOM   3831 N N   . ILE C 2 25  ? 212.924 192.690 230.262 1.00 109.19 ? 264 ILE G N   1 
ATOM   3832 C CA  . ILE C 2 25  ? 213.719 192.326 231.431 1.00 112.84 ? 264 ILE G CA  1 
ATOM   3833 C C   . ILE C 2 25  ? 214.055 193.565 232.247 1.00 110.62 ? 264 ILE G C   1 
ATOM   3834 O O   . ILE C 2 25  ? 214.333 193.470 233.448 1.00 110.10 ? 264 ILE G O   1 
ATOM   3835 C CB  . ILE C 2 25  ? 214.976 191.509 231.036 1.00 113.64 ? 264 ILE G CB  1 
ATOM   3836 C CG1 . ILE C 2 25  ? 215.865 192.186 229.978 1.00 110.89 ? 264 ILE G CG1 1 
ATOM   3837 C CG2 . ILE C 2 25  ? 214.571 190.120 230.558 1.00 112.17 ? 264 ILE G CG2 1 
ATOM   3838 C CD1 . ILE C 2 25  ? 216.681 193.381 230.450 1.00 108.88 ? 264 ILE G CD1 1 
ATOM   3839 N N   . ALA C 2 26  ? 214.031 194.744 231.622 1.00 106.44 ? 265 ALA G N   1 
ATOM   3840 C CA  . ALA C 2 26  ? 214.133 195.970 232.401 1.00 104.03 ? 265 ALA G CA  1 
ATOM   3841 C C   . ALA C 2 26  ? 212.885 196.217 233.238 1.00 103.88 ? 265 ALA G C   1 
ATOM   3842 O O   . ALA C 2 26  ? 212.994 196.488 234.440 1.00 105.92 ? 265 ALA G O   1 
ATOM   3843 C CB  . ALA C 2 26  ? 214.390 197.162 231.479 1.00 103.33 ? 265 ALA G CB  1 
ATOM   3844 N N   . LEU C 2 27  ? 211.701 196.113 232.630 1.00 103.19 ? 266 LEU G N   1 
ATOM   3845 C CA  . LEU C 2 27  ? 210.469 196.444 233.345 1.00 101.96 ? 266 LEU G CA  1 
ATOM   3846 C C   . LEU C 2 27  ? 210.191 195.463 234.478 1.00 101.62 ? 266 LEU G C   1 
ATOM   3847 O O   . LEU C 2 27  ? 209.744 195.864 235.559 1.00 106.71 ? 266 LEU G O   1 
ATOM   3848 C CB  . LEU C 2 27  ? 209.276 196.512 232.386 1.00 103.78 ? 266 LEU G CB  1 
ATOM   3849 C CG  . LEU C 2 27  ? 209.345 197.241 231.042 1.00 107.48 ? 266 LEU G CG  1 
ATOM   3850 C CD1 . LEU C 2 27  ? 207.951 197.670 230.617 1.00 106.67 ? 266 LEU G CD1 1 
ATOM   3851 C CD2 . LEU C 2 27  ? 210.258 198.459 231.110 1.00 104.44 ? 266 LEU G CD2 1 
ATOM   3852 N N   . LYS C 2 28  ? 210.421 194.165 234.249 1.00 96.45  ? 267 LYS G N   1 
ATOM   3853 C CA  . LYS C 2 28  ? 210.150 193.207 235.320 1.00 98.60  ? 267 LYS G CA  1 
ATOM   3854 C C   . LYS C 2 28  ? 211.077 193.420 236.512 1.00 101.72 ? 267 LYS G C   1 
ATOM   3855 O O   . LYS C 2 28  ? 210.629 193.364 237.672 1.00 103.38 ? 267 LYS G O   1 
ATOM   3856 C CB  . LYS C 2 28  ? 210.256 191.770 234.806 1.00 98.79  ? 267 LYS G CB  1 
ATOM   3857 C CG  . LYS C 2 28  ? 211.561 191.416 234.134 1.00 99.51  ? 267 LYS G CG  1 
ATOM   3858 C CD  . LYS C 2 28  ? 211.634 189.925 233.863 1.00 101.26 ? 267 LYS G CD  1 
ATOM   3859 C CE  . LYS C 2 28  ? 210.732 189.535 232.704 1.00 102.33 ? 267 LYS G CE  1 
ATOM   3860 N NZ  . LYS C 2 28  ? 211.229 190.064 231.406 1.00 104.51 ? 267 LYS G NZ  1 
ATOM   3861 N N   . GLU C 2 29  ? 212.365 193.660 236.252 1.00 104.64 ? 268 GLU G N   1 
ATOM   3862 C CA  . GLU C 2 29  ? 213.281 193.986 237.336 1.00 104.52 ? 268 GLU G CA  1 
ATOM   3863 C C   . GLU C 2 29  ? 212.840 195.247 238.052 1.00 103.97 ? 268 GLU G C   1 
ATOM   3864 O O   . GLU C 2 29  ? 212.857 195.293 239.287 1.00 106.09 ? 268 GLU G O   1 
ATOM   3865 C CB  . GLU C 2 29  ? 214.708 194.129 236.809 1.00 104.79 ? 268 GLU G CB  1 
ATOM   3866 C CG  . GLU C 2 29  ? 215.340 192.811 236.396 1.00 106.36 ? 268 GLU G CG  1 
ATOM   3867 C CD  . GLU C 2 29  ? 216.704 192.990 235.766 1.00 110.65 ? 268 GLU G CD  1 
ATOM   3868 O OE1 . GLU C 2 29  ? 217.651 193.354 236.493 1.00 110.68 ? 268 GLU G OE1 1 
ATOM   3869 O OE2 . GLU C 2 29  ? 216.831 192.762 234.545 1.00 112.06 ? 268 GLU G OE2 1 
ATOM   3870 N N   . LEU C 2 30  ? 212.398 196.257 237.300 1.00 96.03  ? 269 LEU G N   1 
ATOM   3871 C CA  . LEU C 2 30  ? 211.893 197.470 237.925 1.00 95.75  ? 269 LEU G CA  1 
ATOM   3872 C C   . LEU C 2 30  ? 210.747 197.164 238.881 1.00 97.81  ? 269 LEU G C   1 
ATOM   3873 O O   . LEU C 2 30  ? 210.779 197.588 240.039 1.00 102.44 ? 269 LEU G O   1 
ATOM   3874 C CB  . LEU C 2 30  ? 211.466 198.474 236.849 1.00 98.42  ? 269 LEU G CB  1 
ATOM   3875 C CG  . LEU C 2 30  ? 210.559 199.670 237.166 1.00 97.90  ? 269 LEU G CG  1 
ATOM   3876 C CD1 . LEU C 2 30  ? 210.838 200.781 236.173 1.00 99.72  ? 269 LEU G CD1 1 
ATOM   3877 C CD2 . LEU C 2 30  ? 209.080 199.312 237.106 1.00 96.10  ? 269 LEU G CD2 1 
ATOM   3878 N N   . GLU C 2 31  ? 209.740 196.411 238.432 1.00 101.31 ? 270 GLU G N   1 
ATOM   3879 C CA  . GLU C 2 31  ? 208.553 196.245 239.270 1.00 99.59  ? 270 GLU G CA  1 
ATOM   3880 C C   . GLU C 2 31  ? 208.853 195.414 240.514 1.00 102.42 ? 270 GLU G C   1 
ATOM   3881 O O   . GLU C 2 31  ? 208.435 195.782 241.626 1.00 105.33 ? 270 GLU G O   1 
ATOM   3882 C CB  . GLU C 2 31  ? 207.393 195.628 238.486 1.00 103.10 ? 270 GLU G CB  1 
ATOM   3883 C CG  . GLU C 2 31  ? 207.764 194.553 237.498 1.00 108.96 ? 270 GLU G CG  1 
ATOM   3884 C CD  . GLU C 2 31  ? 206.804 194.486 236.324 1.00 111.05 ? 270 GLU G CD  1 
ATOM   3885 O OE1 . GLU C 2 31  ? 207.258 194.626 235.169 1.00 107.49 ? 270 GLU G OE1 1 
ATOM   3886 O OE2 . GLU C 2 31  ? 205.593 194.293 236.558 1.00 112.20 ? 270 GLU G OE2 1 
ATOM   3887 N N   . LYS C 2 32  ? 209.567 194.288 240.371 1.00 97.82  ? 271 LYS G N   1 
ATOM   3888 C CA  . LYS C 2 32  ? 209.800 193.525 241.594 1.00 101.42 ? 271 LYS G CA  1 
ATOM   3889 C C   . LYS C 2 32  ? 210.806 194.223 242.503 1.00 105.71 ? 271 LYS G C   1 
ATOM   3890 O O   . LYS C 2 32  ? 210.746 194.058 243.729 1.00 104.35 ? 271 LYS G O   1 
ATOM   3891 C CB  . LYS C 2 32  ? 210.203 192.067 241.339 1.00 99.90  ? 271 LYS G CB  1 
ATOM   3892 C CG  . LYS C 2 32  ? 209.723 191.420 240.054 1.00 102.08 ? 271 LYS G CG  1 
ATOM   3893 C CD  . LYS C 2 32  ? 210.489 190.117 239.801 1.00 103.73 ? 271 LYS G CD  1 
ATOM   3894 C CE  . LYS C 2 32  ? 211.928 190.309 239.398 1.00 104.50 ? 271 LYS G CE  1 
ATOM   3895 N NZ  . LYS C 2 32  ? 212.070 191.447 238.495 1.00 104.87 ? 271 LYS G NZ  1 
ATOM   3896 N N   . GLU C 2 33  ? 211.691 195.056 241.947 1.00 98.93  ? 272 GLU G N   1 
ATOM   3897 C CA  . GLU C 2 33  ? 212.529 195.878 242.808 1.00 93.99  ? 272 GLU G CA  1 
ATOM   3898 C C   . GLU C 2 33  ? 211.701 196.897 243.575 1.00 91.63  ? 272 GLU G C   1 
ATOM   3899 O O   . GLU C 2 33  ? 211.967 197.144 244.756 1.00 93.70  ? 272 GLU G O   1 
ATOM   3900 C CB  . GLU C 2 33  ? 213.611 196.573 241.986 1.00 90.34  ? 272 GLU G CB  1 
ATOM   3901 C CG  . GLU C 2 33  ? 214.829 196.918 242.807 1.00 92.15  ? 272 GLU G CG  1 
ATOM   3902 C CD  . GLU C 2 33  ? 215.522 195.679 243.334 1.00 96.12  ? 272 GLU G CD  1 
ATOM   3903 O OE1 . GLU C 2 33  ? 215.467 194.630 242.659 1.00 93.91  ? 272 GLU G OE1 1 
ATOM   3904 O OE2 . GLU C 2 33  ? 216.105 195.748 244.435 1.00 98.34  ? 272 GLU G OE2 1 
ATOM   3905 N N   . ARG C 2 34  ? 210.689 197.487 242.931 1.00 89.48  ? 273 ARG G N   1 
ATOM   3906 C CA  . ARG C 2 34  ? 209.808 198.413 243.639 1.00 88.69  ? 273 ARG G CA  1 
ATOM   3907 C C   . ARG C 2 34  ? 209.111 197.723 244.802 1.00 90.88  ? 273 ARG G C   1 
ATOM   3908 O O   . ARG C 2 34  ? 209.068 198.259 245.916 1.00 96.76  ? 273 ARG G O   1 
ATOM   3909 C CB  . ARG C 2 34  ? 208.760 199.027 242.701 1.00 92.42  ? 273 ARG G CB  1 
ATOM   3910 C CG  . ARG C 2 34  ? 209.250 199.778 241.463 1.00 96.77  ? 273 ARG G CG  1 
ATOM   3911 C CD  . ARG C 2 34  ? 210.697 200.214 241.551 1.00 93.61  ? 273 ARG G CD  1 
ATOM   3912 N NE  . ARG C 2 34  ? 210.925 201.271 242.524 1.00 93.23  ? 273 ARG G NE  1 
ATOM   3913 C CZ  . ARG C 2 34  ? 212.116 201.800 242.755 1.00 96.30  ? 273 ARG G CZ  1 
ATOM   3914 N NH1 . ARG C 2 34  ? 213.193 201.365 242.124 1.00 93.66  ? 273 ARG G NH1 1 
ATOM   3915 N NH2 . ARG C 2 34  ? 212.231 202.781 243.645 1.00 98.89  ? 273 ARG G NH2 1 
ATOM   3916 N N   . VAL C 2 35  ? 208.556 196.532 244.569 1.00 83.05  ? 274 VAL G N   1 
ATOM   3917 C CA  . VAL C 2 35  ? 207.802 195.896 245.650 1.00 86.29  ? 274 VAL G CA  1 
ATOM   3918 C C   . VAL C 2 35  ? 208.737 195.439 246.772 1.00 90.15  ? 274 VAL G C   1 
ATOM   3919 O O   . VAL C 2 35  ? 208.394 195.536 247.960 1.00 92.91  ? 274 VAL G O   1 
ATOM   3920 C CB  . VAL C 2 35  ? 206.923 194.744 245.129 1.00 89.47  ? 274 VAL G CB  1 
ATOM   3921 C CG1 . VAL C 2 35  ? 205.745 195.293 244.333 1.00 89.35  ? 274 VAL G CG1 1 
ATOM   3922 C CG2 . VAL C 2 35  ? 207.720 193.756 244.322 1.00 91.46  ? 274 VAL G CG2 1 
ATOM   3923 N N   . GLN C 2 36  ? 209.930 194.940 246.427 1.00 82.89  ? 275 GLN G N   1 
ATOM   3924 C CA  . GLN C 2 36  ? 210.870 194.530 247.468 1.00 83.64  ? 275 GLN G CA  1 
ATOM   3925 C C   . GLN C 2 36  ? 211.338 195.729 248.288 1.00 87.02  ? 275 GLN G C   1 
ATOM   3926 O O   . GLN C 2 36  ? 211.450 195.649 249.522 1.00 86.10  ? 275 GLN G O   1 
ATOM   3927 C CB  . GLN C 2 36  ? 212.040 193.766 246.836 1.00 80.68  ? 275 GLN G CB  1 
ATOM   3928 C CG  . GLN C 2 36  ? 213.350 193.703 247.629 1.00 86.01  ? 275 GLN G CG  1 
ATOM   3929 C CD  . GLN C 2 36  ? 214.217 194.944 247.499 1.00 89.52  ? 275 GLN G CD  1 
ATOM   3930 O OE1 . GLN C 2 36  ? 213.858 195.903 246.817 1.00 92.03  ? 275 GLN G OE1 1 
ATOM   3931 N NE2 . GLN C 2 36  ? 215.374 194.922 248.149 1.00 86.40  ? 275 GLN G NE2 1 
ATOM   3932 N N   . LYS C 2 37  ? 211.597 196.858 247.622 1.00 80.83  ? 276 LYS G N   1 
ATOM   3933 C CA  . LYS C 2 37  ? 211.930 198.083 248.335 1.00 76.41  ? 276 LYS G CA  1 
ATOM   3934 C C   . LYS C 2 37  ? 210.787 198.519 249.240 1.00 79.97  ? 276 LYS G C   1 
ATOM   3935 O O   . LYS C 2 37  ? 211.020 199.006 250.351 1.00 87.44  ? 276 LYS G O   1 
ATOM   3936 C CB  . LYS C 2 37  ? 212.278 199.186 247.337 1.00 78.84  ? 276 LYS G CB  1 
ATOM   3937 C CG  . LYS C 2 37  ? 212.228 200.589 247.911 1.00 79.76  ? 276 LYS G CG  1 
ATOM   3938 C CD  . LYS C 2 37  ? 212.251 201.632 246.811 1.00 81.20  ? 276 LYS G CD  1 
ATOM   3939 C CE  . LYS C 2 37  ? 211.095 202.602 246.953 1.00 82.00  ? 276 LYS G CE  1 
ATOM   3940 N NZ  . LYS C 2 37  ? 211.003 203.148 248.334 1.00 84.27  ? 276 LYS G NZ  1 
ATOM   3941 N N   . GLU C 2 38  ? 209.544 198.357 248.781 1.00 79.18  ? 277 GLU G N   1 
ATOM   3942 C CA  . GLU C 2 38  ? 208.400 198.717 249.612 1.00 80.92  ? 277 GLU G CA  1 
ATOM   3943 C C   . GLU C 2 38  ? 208.336 197.865 250.874 1.00 81.72  ? 277 GLU G C   1 
ATOM   3944 O O   . GLU C 2 38  ? 208.068 198.383 251.965 1.00 86.75  ? 277 GLU G O   1 
ATOM   3945 C CB  . GLU C 2 38  ? 207.109 198.585 248.808 1.00 83.48  ? 277 GLU G CB  1 
ATOM   3946 C CG  . GLU C 2 38  ? 206.722 199.847 248.061 1.00 85.64  ? 277 GLU G CG  1 
ATOM   3947 C CD  . GLU C 2 38  ? 206.449 201.009 248.992 1.00 85.15  ? 277 GLU G CD  1 
ATOM   3948 O OE1 . GLU C 2 38  ? 205.875 200.780 250.077 1.00 86.06  ? 277 GLU G OE1 1 
ATOM   3949 O OE2 . GLU C 2 38  ? 206.812 202.151 248.642 1.00 84.77  ? 277 GLU G OE2 1 
ATOM   3950 N N   . GLU C 2 39  ? 208.572 196.558 250.746 1.00 72.87  ? 278 GLU G N   1 
ATOM   3951 C CA  . GLU C 2 39  ? 208.570 195.698 251.930 1.00 75.20  ? 278 GLU G CA  1 
ATOM   3952 C C   . GLU C 2 39  ? 209.681 196.090 252.901 1.00 73.88  ? 278 GLU G C   1 
ATOM   3953 O O   . GLU C 2 39  ? 209.467 196.149 254.124 1.00 70.85  ? 278 GLU G O   1 
ATOM   3954 C CB  . GLU C 2 39  ? 208.715 194.233 251.522 1.00 77.78  ? 278 GLU G CB  1 
ATOM   3955 C CG  . GLU C 2 39  ? 207.658 193.744 250.552 1.00 81.03  ? 278 GLU G CG  1 
ATOM   3956 C CD  . GLU C 2 39  ? 208.153 192.604 249.687 1.00 83.09  ? 278 GLU G CD  1 
ATOM   3957 O OE1 . GLU C 2 39  ? 209.170 191.980 250.053 1.00 82.24  ? 278 GLU G OE1 1 
ATOM   3958 O OE2 . GLU C 2 39  ? 207.525 192.332 248.642 1.00 82.94  ? 278 GLU G OE2 1 
ATOM   3959 N N   . GLU C 2 40  ? 210.878 196.357 252.370 1.00 72.37  ? 279 GLU G N   1 
ATOM   3960 C CA  . GLU C 2 40  ? 211.980 196.782 253.227 1.00 70.70  ? 279 GLU G CA  1 
ATOM   3961 C C   . GLU C 2 40  ? 211.654 198.090 253.936 1.00 70.88  ? 279 GLU G C   1 
ATOM   3962 O O   . GLU C 2 40  ? 211.942 198.246 255.127 1.00 75.85  ? 279 GLU G O   1 
ATOM   3963 C CB  . GLU C 2 40  ? 213.260 196.919 252.406 1.00 73.16  ? 279 GLU G CB  1 
ATOM   3964 C CG  . GLU C 2 40  ? 213.939 195.598 252.100 1.00 75.40  ? 279 GLU G CG  1 
ATOM   3965 C CD  . GLU C 2 40  ? 215.057 195.283 253.071 1.00 78.11  ? 279 GLU G CD  1 
ATOM   3966 O OE1 . GLU C 2 40  ? 215.258 196.067 254.021 1.00 77.04  ? 279 GLU G OE1 1 
ATOM   3967 O OE2 . GLU C 2 40  ? 215.735 194.252 252.885 1.00 78.76  ? 279 GLU G OE2 1 
ATOM   3968 N N   . LEU C 2 41  ? 211.041 199.035 253.223 1.00 71.51  ? 280 LEU G N   1 
ATOM   3969 C CA  . LEU C 2 41  ? 210.639 200.296 253.836 1.00 68.22  ? 280 LEU G CA  1 
ATOM   3970 C C   . LEU C 2 41  ? 209.615 200.075 254.941 1.00 69.97  ? 280 LEU G C   1 
ATOM   3971 O O   . LEU C 2 41  ? 209.704 200.692 256.009 1.00 74.24  ? 280 LEU G O   1 
ATOM   3972 C CB  . LEU C 2 41  ? 210.088 201.232 252.759 1.00 73.53  ? 280 LEU G CB  1 
ATOM   3973 C CG  . LEU C 2 41  ? 209.400 202.537 253.160 1.00 75.81  ? 280 LEU G CG  1 
ATOM   3974 C CD1 . LEU C 2 41  ? 209.789 203.648 252.201 1.00 77.24  ? 280 LEU G CD1 1 
ATOM   3975 C CD2 . LEU C 2 41  ? 207.888 202.372 253.189 1.00 74.26  ? 280 LEU G CD2 1 
ATOM   3976 N N   . GLN C 2 42  ? 208.632 199.206 254.700 1.00 73.80  ? 281 GLN G N   1 
ATOM   3977 C CA  . GLN C 2 42  ? 207.597 198.963 255.701 1.00 74.44  ? 281 GLN G CA  1 
ATOM   3978 C C   . GLN C 2 42  ? 208.207 198.417 256.986 1.00 77.85  ? 281 GLN G C   1 
ATOM   3979 O O   . GLN C 2 42  ? 207.953 198.941 258.081 1.00 79.76  ? 281 GLN G O   1 
ATOM   3980 C CB  . GLN C 2 42  ? 206.561 197.991 255.137 1.00 77.40  ? 281 GLN G CB  1 
ATOM   3981 C CG  . GLN C 2 42  ? 205.354 197.683 256.022 1.00 82.49  ? 281 GLN G CG  1 
ATOM   3982 C CD  . GLN C 2 42  ? 204.900 198.861 256.867 1.00 86.98  ? 281 GLN G CD  1 
ATOM   3983 O OE1 . GLN C 2 42  ? 205.347 199.047 257.997 1.00 87.79  ? 281 GLN G OE1 1 
ATOM   3984 N NE2 . GLN C 2 42  ? 204.005 199.669 256.312 1.00 85.59  ? 281 GLN G NE2 1 
ATOM   3985 N N   . VAL C 2 43  ? 209.050 197.388 256.871 1.00 70.21  ? 282 VAL G N   1 
ATOM   3986 C CA  . VAL C 2 43  ? 209.687 196.859 258.075 1.00 66.09  ? 282 VAL G CA  1 
ATOM   3987 C C   . VAL C 2 43  ? 210.638 197.874 258.713 1.00 65.95  ? 282 VAL G C   1 
ATOM   3988 O O   . VAL C 2 43  ? 210.759 197.914 259.949 1.00 73.09  ? 282 VAL G O   1 
ATOM   3989 C CB  . VAL C 2 43  ? 210.396 195.526 257.771 1.00 68.20  ? 282 VAL G CB  1 
ATOM   3990 C CG1 . VAL C 2 43  ? 211.654 195.739 256.951 1.00 69.17  ? 282 VAL G CG1 1 
ATOM   3991 C CG2 . VAL C 2 43  ? 210.703 194.781 259.062 1.00 68.93  ? 282 VAL G CG2 1 
ATOM   3992 N N   . LYS C 2 44  ? 211.284 198.726 257.911 1.00 65.49  ? 283 LYS G N   1 
ATOM   3993 C CA  . LYS C 2 44  ? 212.174 199.742 258.462 1.00 65.18  ? 283 LYS G CA  1 
ATOM   3994 C C   . LYS C 2 44  ? 211.416 200.741 259.328 1.00 64.19  ? 283 LYS G C   1 
ATOM   3995 O O   . LYS C 2 44  ? 211.863 201.083 260.427 1.00 68.87  ? 283 LYS G O   1 
ATOM   3996 C CB  . LYS C 2 44  ? 212.907 200.457 257.328 1.00 70.92  ? 283 LYS G CB  1 
ATOM   3997 C CG  . LYS C 2 44  ? 213.185 201.923 257.597 1.00 69.63  ? 283 LYS G CG  1 
ATOM   3998 C CD  . LYS C 2 44  ? 214.436 202.088 258.420 1.00 65.17  ? 283 LYS G CD  1 
ATOM   3999 C CE  . LYS C 2 44  ? 215.585 201.336 257.798 1.00 63.15  ? 283 LYS G CE  1 
ATOM   4000 N NZ  . LYS C 2 44  ? 216.855 201.729 258.439 1.00 68.49  ? 283 LYS G NZ  1 
ATOM   4001 N N   . GLU C 2 45  ? 210.273 201.236 258.849 1.00 67.96  ? 284 GLU G N   1 
ATOM   4002 C CA  . GLU C 2 45  ? 209.513 202.164 259.685 1.00 66.63  ? 284 GLU G CA  1 
ATOM   4003 C C   . GLU C 2 45  ? 208.833 201.462 260.851 1.00 74.30  ? 284 GLU G C   1 
ATOM   4004 O O   . GLU C 2 45  ? 208.581 202.096 261.880 1.00 77.28  ? 284 GLU G O   1 
ATOM   4005 C CB  . GLU C 2 45  ? 208.495 202.975 258.873 1.00 73.73  ? 284 GLU G CB  1 
ATOM   4006 C CG  . GLU C 2 45  ? 208.748 203.116 257.382 1.00 83.09  ? 284 GLU G CG  1 
ATOM   4007 C CD  . GLU C 2 45  ? 210.162 203.588 257.046 1.00 87.19  ? 284 GLU G CD  1 
ATOM   4008 O OE1 . GLU C 2 45  ? 210.600 203.389 255.897 1.00 86.97  ? 284 GLU G OE1 1 
ATOM   4009 O OE2 . GLU C 2 45  ? 210.822 204.205 257.910 1.00 86.96  ? 284 GLU G OE2 1 
ATOM   4010 N N   . LYS C 2 46  ? 208.549 200.163 260.737 1.00 73.97  ? 285 LYS G N   1 
ATOM   4011 C CA  . LYS C 2 46  ? 208.118 199.441 261.931 1.00 68.96  ? 285 LYS G CA  1 
ATOM   4012 C C   . LYS C 2 46  ? 209.199 199.469 263.008 1.00 66.82  ? 285 LYS G C   1 
ATOM   4013 O O   . LYS C 2 46  ? 208.910 199.741 264.184 1.00 63.81  ? 285 LYS G O   1 
ATOM   4014 C CB  . LYS C 2 46  ? 207.751 198.001 261.578 1.00 71.14  ? 285 LYS G CB  1 
ATOM   4015 C CG  . LYS C 2 46  ? 207.228 197.192 262.751 1.00 73.33  ? 285 LYS G CG  1 
ATOM   4016 C CD  . LYS C 2 46  ? 206.646 195.867 262.290 1.00 76.15  ? 285 LYS G CD  1 
ATOM   4017 C CE  . LYS C 2 46  ? 205.546 196.074 261.263 1.00 75.68  ? 285 LYS G CE  1 
ATOM   4018 N NZ  . LYS C 2 46  ? 204.592 197.142 261.672 1.00 76.65  ? 285 LYS G NZ  1 
ATOM   4019 N N   . LEU C 2 47  ? 210.451 199.223 262.616 1.00 59.50  ? 286 LEU G N   1 
ATOM   4020 C CA  . LEU C 2 47  ? 211.568 199.330 263.551 1.00 46.95  ? 286 LEU G CA  1 
ATOM   4021 C C   . LEU C 2 47  ? 211.745 200.752 264.082 1.00 55.26  ? 286 LEU G C   1 
ATOM   4022 O O   . LEU C 2 47  ? 212.038 200.933 265.269 1.00 60.06  ? 286 LEU G O   1 
ATOM   4023 C CB  . LEU C 2 47  ? 212.854 198.857 262.876 1.00 49.83  ? 286 LEU G CB  1 
ATOM   4024 C CG  . LEU C 2 47  ? 213.790 198.013 263.738 1.00 56.80  ? 286 LEU G CG  1 
ATOM   4025 C CD1 . LEU C 2 47  ? 213.054 196.795 264.264 1.00 59.59  ? 286 LEU G CD1 1 
ATOM   4026 C CD2 . LEU C 2 47  ? 215.021 197.601 262.949 1.00 58.02  ? 286 LEU G CD2 1 
ATOM   4027 N N   . GLN C 2 48  ? 211.590 201.757 263.216 1.00 68.22  ? 287 GLN G N   1 
ATOM   4028 C CA  . GLN C 2 48  ? 211.614 203.156 263.645 1.00 63.46  ? 287 GLN G CA  1 
ATOM   4029 C C   . GLN C 2 48  ? 210.590 203.427 264.738 1.00 61.05  ? 287 GLN G C   1 
ATOM   4030 O O   . GLN C 2 48  ? 210.907 204.045 265.761 1.00 65.53  ? 287 GLN G O   1 
ATOM   4031 C CB  . GLN C 2 48  ? 211.356 204.072 262.446 1.00 71.11  ? 287 GLN G CB  1 
ATOM   4032 C CG  . GLN C 2 48  ? 212.581 204.495 261.662 1.00 69.90  ? 287 GLN G CG  1 
ATOM   4033 C CD  . GLN C 2 48  ? 213.697 204.980 262.559 1.00 69.74  ? 287 GLN G CD  1 
ATOM   4034 O OE1 . GLN C 2 48  ? 214.539 204.209 263.000 1.00 64.25  ? 287 GLN G OE1 1 
ATOM   4035 N NE2 . GLN C 2 48  ? 213.703 206.277 262.836 1.00 71.36  ? 287 GLN G NE2 1 
ATOM   4036 N N   . GLU C 2 49  ? 209.344 203.005 264.518 1.00 56.45  ? 288 GLU G N   1 
ATOM   4037 C CA  . GLU C 2 49  ? 208.297 203.231 265.508 1.00 59.13  ? 288 GLU G CA  1 
ATOM   4038 C C   . GLU C 2 49  ? 208.628 202.534 266.820 1.00 60.99  ? 288 GLU G C   1 
ATOM   4039 O O   . GLU C 2 49  ? 208.486 203.123 267.901 1.00 58.75  ? 288 GLU G O   1 
ATOM   4040 C CB  . GLU C 2 49  ? 206.955 202.746 264.961 1.00 63.08  ? 288 GLU G CB  1 
ATOM   4041 C CG  . GLU C 2 49  ? 205.793 202.814 265.941 1.00 64.43  ? 288 GLU G CG  1 
ATOM   4042 C CD  . GLU C 2 49  ? 205.765 204.103 266.732 1.00 69.49  ? 288 GLU G CD  1 
ATOM   4043 O OE1 . GLU C 2 49  ? 205.697 205.182 266.108 1.00 69.85  ? 288 GLU G OE1 1 
ATOM   4044 O OE2 . GLU C 2 49  ? 205.801 204.036 267.977 1.00 70.27  ? 288 GLU G OE2 1 
ATOM   4045 N N   . GLU C 2 50  ? 209.088 201.284 266.745 1.00 66.48  ? 289 GLU G N   1 
ATOM   4046 C CA  . GLU C 2 50  ? 209.428 200.564 267.967 1.00 61.47  ? 289 GLU G CA  1 
ATOM   4047 C C   . GLU C 2 50  ? 210.547 201.263 268.730 1.00 60.12  ? 289 GLU G C   1 
ATOM   4048 O O   . GLU C 2 50  ? 210.502 201.353 269.960 1.00 62.66  ? 289 GLU G O   1 
ATOM   4049 C CB  . GLU C 2 50  ? 209.816 199.123 267.645 1.00 61.04  ? 289 GLU G CB  1 
ATOM   4050 C CG  . GLU C 2 50  ? 210.074 198.276 268.876 1.00 54.66  ? 289 GLU G CG  1 
ATOM   4051 C CD  . GLU C 2 50  ? 210.158 196.802 268.560 1.00 62.24  ? 289 GLU G CD  1 
ATOM   4052 O OE1 . GLU C 2 50  ? 209.954 196.432 267.386 1.00 71.79  ? 289 GLU G OE1 1 
ATOM   4053 O OE2 . GLU C 2 50  ? 210.432 196.010 269.484 1.00 64.74  ? 289 GLU G OE2 1 
ATOM   4054 N N   . LEU C 2 51  ? 211.561 201.766 268.021 1.00 58.27  ? 290 LEU G N   1 
ATOM   4055 C CA  . LEU C 2 51  ? 212.666 202.441 268.698 1.00 55.43  ? 290 LEU G CA  1 
ATOM   4056 C C   . LEU C 2 51  ? 212.227 203.767 269.308 1.00 61.18  ? 290 LEU G C   1 
ATOM   4057 O O   . LEU C 2 51  ? 212.636 204.115 270.426 1.00 66.93  ? 290 LEU G O   1 
ATOM   4058 C CB  . LEU C 2 51  ? 213.821 202.663 267.726 1.00 58.72  ? 290 LEU G CB  1 
ATOM   4059 C CG  . LEU C 2 51  ? 215.009 203.368 268.373 1.00 57.73  ? 290 LEU G CG  1 
ATOM   4060 C CD1 . LEU C 2 51  ? 215.462 202.585 269.590 1.00 59.57  ? 290 LEU G CD1 1 
ATOM   4061 C CD2 . LEU C 2 51  ? 216.141 203.560 267.381 1.00 59.51  ? 290 LEU G CD2 1 
ATOM   4062 N N   . ARG C 2 52  ? 211.410 204.531 268.582 1.00 66.85  ? 291 ARG G N   1 
ATOM   4063 C CA  . ARG C 2 52  ? 210.887 205.775 269.131 1.00 60.70  ? 291 ARG G CA  1 
ATOM   4064 C C   . ARG C 2 52  ? 210.091 205.510 270.399 1.00 65.19  ? 291 ARG G C   1 
ATOM   4065 O O   . ARG C 2 52  ? 210.137 206.298 271.349 1.00 61.00  ? 291 ARG G O   1 
ATOM   4066 C CB  . ARG C 2 52  ? 210.029 206.485 268.083 1.00 65.47  ? 291 ARG G CB  1 
ATOM   4067 C CG  . ARG C 2 52  ? 209.707 207.935 268.400 1.00 65.22  ? 291 ARG G CG  1 
ATOM   4068 C CD  . ARG C 2 52  ? 208.383 208.061 269.130 1.00 61.45  ? 291 ARG G CD  1 
ATOM   4069 N NE  . ARG C 2 52  ? 207.246 207.724 268.282 1.00 65.34  ? 291 ARG G NE  1 
ATOM   4070 C CZ  . ARG C 2 52  ? 206.889 208.385 267.189 1.00 72.61  ? 291 ARG G CZ  1 
ATOM   4071 N NH1 . ARG C 2 52  ? 207.533 209.470 266.792 1.00 67.82  ? 291 ARG G NH1 1 
ATOM   4072 N NH2 . ARG C 2 52  ? 205.850 207.953 266.481 1.00 72.84  ? 291 ARG G NH2 1 
ATOM   4073 N N   . TRP C 2 53  ? 209.355 204.401 270.430 1.00 77.38  ? 292 TRP G N   1 
ATOM   4074 C CA  . TRP C 2 53  ? 208.706 203.988 271.667 1.00 72.29  ? 292 TRP G CA  1 
ATOM   4075 C C   . TRP C 2 53  ? 209.720 203.618 272.746 1.00 64.21  ? 292 TRP G C   1 
ATOM   4076 O O   . TRP C 2 53  ? 209.578 204.046 273.896 1.00 51.80  ? 292 TRP G O   1 
ATOM   4077 C CB  . TRP C 2 53  ? 207.765 202.816 271.382 1.00 75.10  ? 292 TRP G CB  1 
ATOM   4078 C CG  . TRP C 2 53  ? 207.155 202.200 272.595 1.00 70.41  ? 292 TRP G CG  1 
ATOM   4079 C CD1 . TRP C 2 53  ? 206.020 202.599 273.233 1.00 69.37  ? 292 TRP G CD1 1 
ATOM   4080 C CD2 . TRP C 2 53  ? 207.636 201.057 273.308 1.00 68.19  ? 292 TRP G CD2 1 
ATOM   4081 N NE1 . TRP C 2 53  ? 205.768 201.781 274.306 1.00 77.19  ? 292 TRP G NE1 1 
ATOM   4082 C CE2 . TRP C 2 53  ? 206.746 200.826 274.373 1.00 74.62  ? 292 TRP G CE2 1 
ATOM   4083 C CE3 . TRP C 2 53  ? 208.735 200.210 273.152 1.00 60.74  ? 292 TRP G CE3 1 
ATOM   4084 C CZ2 . TRP C 2 53  ? 206.922 199.784 275.278 1.00 75.92  ? 292 TRP G CZ2 1 
ATOM   4085 C CZ3 . TRP C 2 53  ? 208.908 199.180 274.048 1.00 60.53  ? 292 TRP G CZ3 1 
ATOM   4086 C CH2 . TRP C 2 53  ? 208.007 198.973 275.098 1.00 73.40  ? 292 TRP G CH2 1 
ATOM   4087 N N   . ARG C 2 54  ? 210.736 202.832 272.398 1.00 60.94  ? 293 ARG G N   1 
ATOM   4088 C CA  . ARG C 2 54  ? 211.778 202.410 273.336 1.00 51.70  ? 293 ARG G CA  1 
ATOM   4089 C C   . ARG C 2 54  ? 213.010 203.309 273.273 1.00 49.15  ? 293 ARG G C   1 
ATOM   4090 O O   . ARG C 2 54  ? 214.140 202.838 273.158 1.00 51.80  ? 293 ARG G O   1 
ATOM   4091 C CB  . ARG C 2 54  ? 212.153 200.958 273.060 1.00 56.01  ? 293 ARG G CB  1 
ATOM   4092 C CG  . ARG C 2 54  ? 212.868 200.253 274.203 1.00 58.91  ? 293 ARG G CG  1 
ATOM   4093 C CD  . ARG C 2 54  ? 213.422 198.918 273.747 1.00 49.76  ? 293 ARG G CD  1 
ATOM   4094 N NE  . ARG C 2 54  ? 212.407 198.132 273.059 1.00 49.71  ? 293 ARG G NE  1 
ATOM   4095 C CZ  . ARG C 2 54  ? 211.543 197.332 273.665 1.00 49.38  ? 293 ARG G CZ  1 
ATOM   4096 N NH1 . ARG C 2 54  ? 211.552 197.173 274.977 1.00 53.85  ? 293 ARG G NH1 1 
ATOM   4097 N NH2 . ARG C 2 54  ? 210.645 196.676 272.936 1.00 55.34  ? 293 ARG G NH2 1 
ATOM   4098 N N   . ARG C 2 55  ? 212.805 204.619 273.339 1.00 57.51  ? 294 ARG G N   1 
ATOM   4099 C CA  . ARG C 2 55  ? 213.915 205.539 273.545 1.00 60.18  ? 294 ARG G CA  1 
ATOM   4100 C C   . ARG C 2 55  ? 213.635 206.605 274.594 1.00 57.29  ? 294 ARG G C   1 
ATOM   4101 O O   . ARG C 2 55  ? 214.506 207.446 274.835 1.00 53.22  ? 294 ARG G O   1 
ATOM   4102 C CB  . ARG C 2 55  ? 214.313 206.218 272.226 1.00 68.80  ? 294 ARG G CB  1 
ATOM   4103 C CG  . ARG C 2 55  ? 215.697 205.827 271.728 1.00 63.37  ? 294 ARG G CG  1 
ATOM   4104 C CD  . ARG C 2 55  ? 216.369 206.978 270.998 1.00 66.21  ? 294 ARG G CD  1 
ATOM   4105 N NE  . ARG C 2 55  ? 215.401 207.851 270.344 1.00 71.88  ? 294 ARG G NE  1 
ATOM   4106 C CZ  . ARG C 2 55  ? 215.049 207.758 269.070 1.00 69.61  ? 294 ARG G CZ  1 
ATOM   4107 N NH1 . ARG C 2 55  ? 215.571 206.841 268.274 1.00 66.55  ? 294 ARG G NH1 1 
ATOM   4108 N NH2 . ARG C 2 55  ? 214.150 208.608 268.582 1.00 67.65  ? 294 ARG G NH2 1 
ATOM   4109 N N   . THR C 2 56  ? 212.459 206.603 275.220 1.00 55.66  ? 295 THR G N   1 
ATOM   4110 C CA  . THR C 2 56  ? 212.135 207.511 276.312 1.00 54.10  ? 295 THR G CA  1 
ATOM   4111 C C   . THR C 2 56  ? 212.228 206.829 277.672 1.00 56.11  ? 295 THR G C   1 
ATOM   4112 O O   . THR C 2 56  ? 211.470 207.162 278.588 1.00 60.71  ? 295 THR G O   1 
ATOM   4113 C CB  . THR C 2 56  ? 210.739 208.102 276.114 1.00 54.69  ? 295 THR G CB  1 
ATOM   4114 O OG1 . THR C 2 56  ? 210.360 208.843 277.279 1.00 56.51  ? 295 THR G OG1 1 
ATOM   4115 C CG2 . THR C 2 56  ? 209.723 207.002 275.869 1.00 57.80  ? 295 THR G CG2 1 
ATOM   4116 N N   . PHE C 2 57  ? 213.147 205.881 277.823 1.00 50.46  ? 296 PHE G N   1 
ATOM   4117 C CA  . PHE C 2 57  ? 213.249 205.064 279.022 1.00 45.09  ? 296 PHE G CA  1 
ATOM   4118 C C   . PHE C 2 57  ? 214.541 205.371 279.763 1.00 47.09  ? 296 PHE G C   1 
ATOM   4119 O O   . PHE C 2 57  ? 215.579 205.625 279.144 1.00 52.34  ? 296 PHE G O   1 
ATOM   4120 C CB  . PHE C 2 57  ? 213.199 203.574 278.677 1.00 40.40  ? 296 PHE G CB  1 
ATOM   4121 C CG  . PHE C 2 57  ? 211.826 203.074 278.339 1.00 39.17  ? 296 PHE G CG  1 
ATOM   4122 C CD1 . PHE C 2 57  ? 210.723 203.897 278.463 1.00 42.54  ? 296 PHE G CD1 1 
ATOM   4123 C CD2 . PHE C 2 57  ? 211.641 201.777 277.900 1.00 41.63  ? 296 PHE G CD2 1 
ATOM   4124 C CE1 . PHE C 2 57  ? 209.461 203.437 278.151 1.00 49.94  ? 296 PHE G CE1 1 
ATOM   4125 C CE2 . PHE C 2 57  ? 210.381 201.312 277.588 1.00 45.66  ? 296 PHE G CE2 1 
ATOM   4126 C CZ  . PHE C 2 57  ? 209.290 202.144 277.715 1.00 49.97  ? 296 PHE G CZ  1 
ATOM   4127 N N   . LEU C 2 58  ? 214.471 205.347 281.090 1.00 41.17  ? 297 LEU G N   1 
ATOM   4128 C CA  . LEU C 2 58  ? 215.645 205.514 281.936 1.00 39.06  ? 297 LEU G CA  1 
ATOM   4129 C C   . LEU C 2 58  ? 216.209 204.135 282.255 1.00 45.59  ? 297 LEU G C   1 
ATOM   4130 O O   . LEU C 2 58  ? 215.479 203.254 282.722 1.00 48.05  ? 297 LEU G O   1 
ATOM   4131 C CB  . LEU C 2 58  ? 215.285 206.271 283.213 1.00 35.39  ? 297 LEU G CB  1 
ATOM   4132 C CG  . LEU C 2 58  ? 216.396 206.508 284.235 1.00 36.14  ? 297 LEU G CG  1 
ATOM   4133 C CD1 . LEU C 2 58  ? 217.599 207.164 283.589 1.00 35.57  ? 297 LEU G CD1 1 
ATOM   4134 C CD2 . LEU C 2 58  ? 215.881 207.354 285.382 1.00 41.64  ? 297 LEU G CD2 1 
ATOM   4135 N N   . HIS C 2 59  ? 217.499 203.946 282.001 1.00 47.16  ? 298 HIS G N   1 
ATOM   4136 C CA  . HIS C 2 59  ? 218.135 202.640 282.112 1.00 50.60  ? 298 HIS G CA  1 
ATOM   4137 C C   . HIS C 2 59  ? 219.057 202.620 283.324 1.00 50.85  ? 298 HIS G C   1 
ATOM   4138 O O   . HIS C 2 59  ? 219.980 203.435 283.419 1.00 54.91  ? 298 HIS G O   1 
ATOM   4139 C CB  . HIS C 2 59  ? 218.920 202.311 280.843 1.00 51.75  ? 298 HIS G CB  1 
ATOM   4140 C CG  . HIS C 2 59  ? 218.068 202.178 279.618 1.00 63.89  ? 298 HIS G CG  1 
ATOM   4141 N ND1 . HIS C 2 59  ? 218.431 201.396 278.543 1.00 63.12  ? 298 HIS G ND1 1 
ATOM   4142 C CD2 . HIS C 2 59  ? 216.871 202.724 279.298 1.00 63.37  ? 298 HIS G CD2 1 
ATOM   4143 C CE1 . HIS C 2 59  ? 217.495 201.466 277.613 1.00 62.38  ? 298 HIS G CE1 1 
ATOM   4144 N NE2 . HIS C 2 59  ? 216.537 202.266 278.047 1.00 63.66  ? 298 HIS G NE2 1 
ATOM   4145 N N   . ALA C 2 60  ? 218.810 201.689 284.242 1.00 43.50  ? 299 ALA G N   1 
ATOM   4146 C CA  . ALA C 2 60  ? 219.702 201.476 285.376 1.00 41.50  ? 299 ALA G CA  1 
ATOM   4147 C C   . ALA C 2 60  ? 220.912 200.691 284.889 1.00 49.25  ? 299 ALA G C   1 
ATOM   4148 O O   . ALA C 2 60  ? 220.805 199.501 284.577 1.00 57.07  ? 299 ALA G O   1 
ATOM   4149 C CB  . ALA C 2 60  ? 218.978 200.745 286.502 1.00 39.47  ? 299 ALA G CB  1 
ATOM   4150 N N   . VAL C 2 61  ? 222.060 201.351 284.820 1.00 48.93  ? 300 VAL G N   1 
ATOM   4151 C CA  . VAL C 2 61  ? 223.256 200.772 284.223 1.00 45.48  ? 300 VAL G CA  1 
ATOM   4152 C C   . VAL C 2 61  ? 224.039 200.016 285.287 1.00 44.21  ? 300 VAL G C   1 
ATOM   4153 O O   . VAL C 2 61  ? 224.313 200.548 286.369 1.00 45.80  ? 300 VAL G O   1 
ATOM   4154 C CB  . VAL C 2 61  ? 224.122 201.860 283.569 1.00 43.67  ? 300 VAL G CB  1 
ATOM   4155 C CG1 . VAL C 2 61  ? 225.501 201.322 283.248 1.00 50.51  ? 300 VAL G CG1 1 
ATOM   4156 C CG2 . VAL C 2 61  ? 223.450 202.378 282.316 1.00 42.65  ? 300 VAL G CG2 1 
ATOM   4157 N N   . ASP C 2 62  ? 224.390 198.769 284.983 1.00 48.57  ? 301 ASP G N   1 
ATOM   4158 C CA  . ASP C 2 62  ? 225.269 197.966 285.831 1.00 55.24  ? 301 ASP G CA  1 
ATOM   4159 C C   . ASP C 2 62  ? 226.701 198.284 285.422 1.00 49.00  ? 301 ASP G C   1 
ATOM   4160 O O   . ASP C 2 62  ? 227.256 197.689 284.499 1.00 57.56  ? 301 ASP G O   1 
ATOM   4161 C CB  . ASP C 2 62  ? 224.951 196.482 285.690 1.00 69.97  ? 301 ASP G CB  1 
ATOM   4162 C CG  . ASP C 2 62  ? 225.458 195.659 286.861 1.00 69.19  ? 301 ASP G CG  1 
ATOM   4163 O OD1 . ASP C 2 62  ? 225.153 196.018 288.017 1.00 69.41  ? 301 ASP G OD1 1 
ATOM   4164 O OD2 . ASP C 2 62  ? 226.157 194.651 286.627 1.00 57.75  ? 301 ASP G OD2 1 
ATOM   4165 N N   . VAL C 2 63  ? 227.306 199.245 286.117 1.00 32.64  ? 302 VAL G N   1 
ATOM   4166 C CA  . VAL C 2 63  ? 228.641 199.702 285.755 1.00 36.15  ? 302 VAL G CA  1 
ATOM   4167 C C   . VAL C 2 63  ? 229.672 198.678 286.206 1.00 38.48  ? 302 VAL G C   1 
ATOM   4168 O O   . VAL C 2 63  ? 229.687 198.254 287.368 1.00 49.40  ? 302 VAL G O   1 
ATOM   4169 C CB  . VAL C 2 63  ? 228.918 201.084 286.366 1.00 44.80  ? 302 VAL G CB  1 
ATOM   4170 C CG1 . VAL C 2 63  ? 230.410 201.297 286.562 1.00 45.04  ? 302 VAL G CG1 1 
ATOM   4171 C CG2 . VAL C 2 63  ? 228.334 202.172 285.485 1.00 49.68  ? 302 VAL G CG2 1 
ATOM   4172 N N   . VAL C 2 64  ? 230.531 198.264 285.279 1.00 48.47  ? 303 VAL G N   1 
ATOM   4173 C CA  . VAL C 2 64  ? 231.680 197.417 285.570 1.00 50.83  ? 303 VAL G CA  1 
ATOM   4174 C C   . VAL C 2 64  ? 232.921 198.144 285.080 1.00 58.68  ? 303 VAL G C   1 
ATOM   4175 O O   . VAL C 2 64  ? 232.934 198.672 283.962 1.00 71.06  ? 303 VAL G O   1 
ATOM   4176 C CB  . VAL C 2 64  ? 231.559 196.031 284.910 1.00 58.66  ? 303 VAL G CB  1 
ATOM   4177 C CG1 . VAL C 2 64  ? 232.596 195.082 285.484 1.00 58.27  ? 303 VAL G CG1 1 
ATOM   4178 C CG2 . VAL C 2 64  ? 230.159 195.471 285.096 1.00 62.85  ? 303 VAL G CG2 1 
ATOM   4179 N N   . LEU C 2 65  ? 233.953 198.179 285.910 1.00 60.21  ? 304 LEU G N   1 
ATOM   4180 C CA  . LEU C 2 65  ? 235.152 198.936 285.593 1.00 60.87  ? 304 LEU G CA  1 
ATOM   4181 C C   . LEU C 2 65  ? 236.130 198.102 284.770 1.00 61.76  ? 304 LEU G C   1 
ATOM   4182 O O   . LEU C 2 65  ? 235.911 196.922 284.488 1.00 59.26  ? 304 LEU G O   1 
ATOM   4183 C CB  . LEU C 2 65  ? 235.825 199.425 286.873 1.00 56.99  ? 304 LEU G CB  1 
ATOM   4184 C CG  . LEU C 2 65  ? 234.903 200.051 287.917 1.00 61.87  ? 304 LEU G CG  1 
ATOM   4185 C CD1 . LEU C 2 65  ? 235.703 200.458 289.133 1.00 65.33  ? 304 LEU G CD1 1 
ATOM   4186 C CD2 . LEU C 2 65  ? 234.165 201.241 287.336 1.00 65.21  ? 304 LEU G CD2 1 
ATOM   4187 N N   . ASP C 2 66  ? 237.222 198.743 284.380 1.00 78.63  ? 305 ASP G N   1 
ATOM   4188 C CA  . ASP C 2 66  ? 238.324 198.093 283.674 1.00 76.56  ? 305 ASP G CA  1 
ATOM   4189 C C   . ASP C 2 66  ? 239.585 198.271 284.504 1.00 82.90  ? 305 ASP G C   1 
ATOM   4190 O O   . ASP C 2 66  ? 240.065 199.411 284.653 1.00 92.88  ? 305 ASP G O   1 
ATOM   4191 C CB  . ASP C 2 66  ? 238.501 198.699 282.282 1.00 77.05  ? 305 ASP G CB  1 
ATOM   4192 C CG  . ASP C 2 66  ? 239.695 198.130 281.536 1.00 83.14  ? 305 ASP G CG  1 
ATOM   4193 O OD1 . ASP C 2 66  ? 240.098 196.985 281.818 1.00 83.90  ? 305 ASP G OD1 1 
ATOM   4194 O OD2 . ASP C 2 66  ? 240.234 198.834 280.659 1.00 84.03  ? 305 ASP G OD2 1 
ATOM   4195 N N   . PRO C 2 67  ? 240.167 197.207 285.063 1.00 84.33  ? 306 PRO G N   1 
ATOM   4196 C CA  . PRO C 2 67  ? 241.346 197.375 285.916 1.00 89.92  ? 306 PRO G CA  1 
ATOM   4197 C C   . PRO C 2 67  ? 242.628 197.674 285.159 1.00 91.88  ? 306 PRO G C   1 
ATOM   4198 O O   . PRO C 2 67  ? 243.658 197.923 285.795 1.00 89.14  ? 306 PRO G O   1 
ATOM   4199 C CB  . PRO C 2 67  ? 241.424 196.027 286.644 1.00 91.32  ? 306 PRO G CB  1 
ATOM   4200 C CG  . PRO C 2 67  ? 240.771 195.037 285.705 1.00 88.62  ? 306 PRO G CG  1 
ATOM   4201 C CD  . PRO C 2 67  ? 240.030 195.807 284.630 1.00 82.90  ? 306 PRO G CD  1 
ATOM   4202 N N   . ASP C 2 68  ? 242.593 197.654 283.826 1.00 93.82  ? 307 ASP G N   1 
ATOM   4203 C CA  . ASP C 2 68  ? 243.751 198.074 283.048 1.00 90.71  ? 307 ASP G CA  1 
ATOM   4204 C C   . ASP C 2 68  ? 243.856 199.597 283.052 1.00 87.24  ? 307 ASP G C   1 
ATOM   4205 O O   . ASP C 2 68  ? 244.952 200.151 283.191 1.00 81.73  ? 307 ASP G O   1 
ATOM   4206 C CB  . ASP C 2 68  ? 243.625 197.487 281.631 1.00 91.78  ? 307 ASP G CB  1 
ATOM   4207 C CG  . ASP C 2 68  ? 244.447 198.219 280.560 1.00 95.92  ? 307 ASP G CG  1 
ATOM   4208 O OD1 . ASP C 2 68  ? 245.296 199.082 280.856 1.00 96.27  ? 307 ASP G OD1 1 
ATOM   4209 O OD2 . ASP C 2 68  ? 244.226 197.910 279.371 1.00 96.42  ? 307 ASP G OD2 1 
ATOM   4210 N N   . THR C 2 69  ? 242.719 200.288 282.966 1.00 80.68  ? 308 THR G N   1 
ATOM   4211 C CA  . THR C 2 69  ? 242.677 201.736 282.814 1.00 80.15  ? 308 THR G CA  1 
ATOM   4212 C C   . THR C 2 69  ? 242.643 202.474 284.146 1.00 83.79  ? 308 THR G C   1 
ATOM   4213 O O   . THR C 2 69  ? 242.114 203.589 284.211 1.00 87.04  ? 308 THR G O   1 
ATOM   4214 C CB  . THR C 2 69  ? 241.467 202.144 281.972 1.00 80.57  ? 308 THR G CB  1 
ATOM   4215 O OG1 . THR C 2 69  ? 240.284 201.542 282.509 1.00 80.03  ? 308 THR G OG1 1 
ATOM   4216 C CG2 . THR C 2 69  ? 241.647 201.701 280.532 1.00 82.09  ? 308 THR G CG2 1 
ATOM   4217 N N   . ALA C 2 70  ? 243.185 201.883 285.203 1.00 87.98  ? 309 ALA G N   1 
ATOM   4218 C CA  . ALA C 2 70  ? 243.278 202.532 286.499 1.00 85.46  ? 309 ALA G CA  1 
ATOM   4219 C C   . ALA C 2 70  ? 244.733 202.836 286.830 1.00 86.87  ? 309 ALA G C   1 
ATOM   4220 O O   . ALA C 2 70  ? 245.659 202.274 286.240 1.00 91.54  ? 309 ALA G O   1 
ATOM   4221 C CB  . ALA C 2 70  ? 242.663 201.660 287.598 1.00 86.36  ? 309 ALA G CB  1 
ATOM   4222 N N   . HIS C 2 71  ? 244.921 203.747 287.776 1.00 93.03  ? 310 HIS G N   1 
ATOM   4223 C CA  . HIS C 2 71  ? 246.254 204.015 288.287 1.00 95.53  ? 310 HIS G CA  1 
ATOM   4224 C C   . HIS C 2 71  ? 246.827 202.741 288.903 1.00 100.63 ? 310 HIS G C   1 
ATOM   4225 O O   . HIS C 2 71  ? 246.112 202.019 289.609 1.00 104.09 ? 310 HIS G O   1 
ATOM   4226 C CB  . HIS C 2 71  ? 246.209 205.129 289.335 1.00 96.82  ? 310 HIS G CB  1 
ATOM   4227 C CG  . HIS C 2 71  ? 247.355 206.089 289.259 1.00 93.80  ? 310 HIS G CG  1 
ATOM   4228 N ND1 . HIS C 2 71  ? 247.294 207.361 289.785 1.00 93.61  ? 310 HIS G ND1 1 
ATOM   4229 C CD2 . HIS C 2 71  ? 248.594 205.962 288.728 1.00 95.80  ? 310 HIS G CD2 1 
ATOM   4230 C CE1 . HIS C 2 71  ? 248.443 207.978 289.579 1.00 98.46  ? 310 HIS G CE1 1 
ATOM   4231 N NE2 . HIS C 2 71  ? 249.250 207.151 288.940 1.00 100.44 ? 310 HIS G NE2 1 
ATOM   4232 N N   . PRO C 2 72  ? 248.099 202.423 288.648 1.00 109.29 ? 311 PRO G N   1 
ATOM   4233 C CA  . PRO C 2 72  ? 248.691 201.227 289.270 1.00 112.15 ? 311 PRO G CA  1 
ATOM   4234 C C   . PRO C 2 72  ? 248.640 201.239 290.786 1.00 111.83 ? 311 PRO G C   1 
ATOM   4235 O O   . PRO C 2 72  ? 248.683 200.165 291.398 1.00 115.70 ? 311 PRO G O   1 
ATOM   4236 C CB  . PRO C 2 72  ? 250.136 201.250 288.759 1.00 110.53 ? 311 PRO G CB  1 
ATOM   4237 C CG  . PRO C 2 72  ? 250.047 201.939 287.445 1.00 110.68 ? 311 PRO G CG  1 
ATOM   4238 C CD  . PRO C 2 72  ? 248.940 202.954 287.562 1.00 107.17 ? 311 PRO G CD  1 
ATOM   4239 N N   . ASP C 2 73  ? 248.550 202.413 291.412 1.00 110.02 ? 312 ASP G N   1 
ATOM   4240 C CA  . ASP C 2 73  ? 248.453 202.467 292.865 1.00 108.22 ? 312 ASP G CA  1 
ATOM   4241 C C   . ASP C 2 73  ? 247.123 201.904 293.357 1.00 110.21 ? 312 ASP G C   1 
ATOM   4242 O O   . ASP C 2 73  ? 247.053 201.360 294.464 1.00 114.25 ? 312 ASP G O   1 
ATOM   4243 C CB  . ASP C 2 73  ? 248.633 203.911 293.337 1.00 111.29 ? 312 ASP G CB  1 
ATOM   4244 C CG  . ASP C 2 73  ? 248.866 204.019 294.833 1.00 117.63 ? 312 ASP G CG  1 
ATOM   4245 O OD1 . ASP C 2 73  ? 248.892 202.979 295.520 1.00 117.78 ? 312 ASP G OD1 1 
ATOM   4246 O OD2 . ASP C 2 73  ? 249.063 205.152 295.318 1.00 119.61 ? 312 ASP G OD2 1 
ATOM   4247 N N   . LEU C 2 74  ? 246.071 202.004 292.548 1.00 95.25  ? 313 LEU G N   1 
ATOM   4248 C CA  . LEU C 2 74  ? 244.737 201.611 292.978 1.00 96.28  ? 313 LEU G CA  1 
ATOM   4249 C C   . LEU C 2 74  ? 244.634 200.097 293.150 1.00 100.77 ? 313 LEU G C   1 
ATOM   4250 O O   . LEU C 2 74  ? 245.459 199.326 292.654 1.00 103.03 ? 313 LEU G O   1 
ATOM   4251 C CB  . LEU C 2 74  ? 243.690 202.085 291.970 1.00 90.96  ? 313 LEU G CB  1 
ATOM   4252 C CG  . LEU C 2 74  ? 243.377 203.580 291.943 1.00 92.93  ? 313 LEU G CG  1 
ATOM   4253 C CD1 . LEU C 2 74  ? 242.557 203.923 290.713 1.00 97.32  ? 313 LEU G CD1 1 
ATOM   4254 C CD2 . LEU C 2 74  ? 242.650 204.001 293.205 1.00 96.37  ? 313 LEU G CD2 1 
ATOM   4255 N N   . PHE C 2 75  ? 243.596 199.677 293.874 1.00 109.19 ? 314 PHE G N   1 
ATOM   4256 C CA  . PHE C 2 75  ? 243.271 198.271 294.063 1.00 105.32 ? 314 PHE G CA  1 
ATOM   4257 C C   . PHE C 2 75  ? 241.802 198.085 293.715 1.00 104.01 ? 314 PHE G C   1 
ATOM   4258 O O   . PHE C 2 75  ? 240.959 198.901 294.106 1.00 107.29 ? 314 PHE G O   1 
ATOM   4259 C CB  . PHE C 2 75  ? 243.545 197.823 295.505 1.00 104.31 ? 314 PHE G CB  1 
ATOM   4260 C CG  . PHE C 2 75  ? 242.532 196.851 296.049 1.00 109.20 ? 314 PHE G CG  1 
ATOM   4261 C CD1 . PHE C 2 75  ? 242.424 195.569 295.526 1.00 110.57 ? 314 PHE G CD1 1 
ATOM   4262 C CD2 . PHE C 2 75  ? 241.675 197.223 297.070 1.00 108.92 ? 314 PHE G CD2 1 
ATOM   4263 C CE1 . PHE C 2 75  ? 241.492 194.678 296.020 1.00 110.09 ? 314 PHE G CE1 1 
ATOM   4264 C CE2 . PHE C 2 75  ? 240.739 196.334 297.565 1.00 110.71 ? 314 PHE G CE2 1 
ATOM   4265 C CZ  . PHE C 2 75  ? 240.649 195.062 297.041 1.00 111.31 ? 314 PHE G CZ  1 
ATOM   4266 N N   . LEU C 2 76  ? 241.501 197.019 292.983 1.00 83.85  ? 315 LEU G N   1 
ATOM   4267 C CA  . LEU C 2 76  ? 240.156 196.745 292.504 1.00 81.87  ? 315 LEU G CA  1 
ATOM   4268 C C   . LEU C 2 76  ? 239.680 195.398 293.026 1.00 85.23  ? 315 LEU G C   1 
ATOM   4269 O O   . LEU C 2 76  ? 240.435 194.421 293.030 1.00 85.29  ? 315 LEU G O   1 
ATOM   4270 C CB  . LEU C 2 76  ? 240.112 196.756 290.975 1.00 82.69  ? 315 LEU G CB  1 
ATOM   4271 C CG  . LEU C 2 76  ? 240.798 197.938 290.289 1.00 86.91  ? 315 LEU G CG  1 
ATOM   4272 C CD1 . LEU C 2 76  ? 242.194 197.561 289.828 1.00 87.74  ? 315 LEU G CD1 1 
ATOM   4273 C CD2 . LEU C 2 76  ? 239.961 198.428 289.122 1.00 87.78  ? 315 LEU G CD2 1 
ATOM   4274 N N   . SER C 2 77  ? 238.425 195.351 293.463 1.00 79.29  ? 316 SER G N   1 
ATOM   4275 C CA  . SER C 2 77  ? 237.836 194.095 293.899 1.00 76.01  ? 316 SER G CA  1 
ATOM   4276 C C   . SER C 2 77  ? 237.696 193.141 292.721 1.00 76.87  ? 316 SER G C   1 
ATOM   4277 O O   . SER C 2 77  ? 237.504 193.557 291.576 1.00 83.21  ? 316 SER G O   1 
ATOM   4278 C CB  . SER C 2 77  ? 236.471 194.336 294.539 1.00 74.63  ? 316 SER G CB  1 
ATOM   4279 O OG  . SER C 2 77  ? 235.441 194.265 293.569 1.00 76.04  ? 316 SER G OG  1 
ATOM   4280 N N   . GLU C 2 78  ? 237.804 191.843 293.011 1.00 75.80  ? 317 GLU G N   1 
ATOM   4281 C CA  . GLU C 2 78  ? 237.742 190.845 291.949 1.00 76.15  ? 317 GLU G CA  1 
ATOM   4282 C C   . GLU C 2 78  ? 236.397 190.873 291.236 1.00 78.75  ? 317 GLU G C   1 
ATOM   4283 O O   . GLU C 2 78  ? 236.324 190.588 290.036 1.00 80.97  ? 317 GLU G O   1 
ATOM   4284 C CB  . GLU C 2 78  ? 238.021 189.452 292.518 1.00 80.27  ? 317 GLU G CB  1 
ATOM   4285 C CG  . GLU C 2 78  ? 238.025 188.288 291.509 1.00 86.84  ? 317 GLU G CG  1 
ATOM   4286 C CD  . GLU C 2 78  ? 238.598 188.623 290.131 1.00 89.43  ? 317 GLU G CD  1 
ATOM   4287 O OE1 . GLU C 2 78  ? 239.489 189.495 290.014 1.00 85.80  ? 317 GLU G OE1 1 
ATOM   4288 O OE2 . GLU C 2 78  ? 238.145 188.003 289.147 1.00 89.97  ? 317 GLU G OE2 1 
ATOM   4289 N N   . ASP C 2 79  ? 235.326 191.224 291.948 1.00 67.99  ? 318 ASP G N   1 
ATOM   4290 C CA  . ASP C 2 79  ? 234.027 191.399 291.313 1.00 66.23  ? 318 ASP G CA  1 
ATOM   4291 C C   . ASP C 2 79  ? 233.989 192.604 290.384 1.00 71.06  ? 318 ASP G C   1 
ATOM   4292 O O   . ASP C 2 79  ? 233.033 192.736 289.613 1.00 69.63  ? 318 ASP G O   1 
ATOM   4293 C CB  . ASP C 2 79  ? 232.938 191.532 292.378 1.00 68.45  ? 318 ASP G CB  1 
ATOM   4294 C CG  . ASP C 2 79  ? 231.722 190.683 292.074 1.00 71.58  ? 318 ASP G CG  1 
ATOM   4295 O OD1 . ASP C 2 79  ? 231.713 190.015 291.019 1.00 70.28  ? 318 ASP G OD1 1 
ATOM   4296 O OD2 . ASP C 2 79  ? 230.776 190.682 292.889 1.00 70.45  ? 318 ASP G OD2 1 
ATOM   4297 N N   . ARG C 2 80  ? 234.997 193.477 290.447 1.00 76.84  ? 319 ARG G N   1 
ATOM   4298 C CA  . ARG C 2 80  ? 235.113 194.638 289.564 1.00 68.42  ? 319 ARG G CA  1 
ATOM   4299 C C   . ARG C 2 80  ? 233.927 195.586 289.721 1.00 67.03  ? 319 ARG G C   1 
ATOM   4300 O O   . ARG C 2 80  ? 233.420 196.142 288.746 1.00 72.43  ? 319 ARG G O   1 
ATOM   4301 C CB  . ARG C 2 80  ? 235.277 194.205 288.106 1.00 67.52  ? 319 ARG G CB  1 
ATOM   4302 C CG  . ARG C 2 80  ? 236.209 195.088 287.298 1.00 73.20  ? 319 ARG G CG  1 
ATOM   4303 C CD  . ARG C 2 80  ? 237.640 195.008 287.804 1.00 71.40  ? 319 ARG G CD  1 
ATOM   4304 N NE  . ARG C 2 80  ? 237.974 193.686 288.320 1.00 67.29  ? 319 ARG G NE  1 
ATOM   4305 C CZ  . ARG C 2 80  ? 238.345 192.661 287.568 1.00 68.77  ? 319 ARG G CZ  1 
ATOM   4306 N NH1 . ARG C 2 80  ? 238.423 192.762 286.252 1.00 67.45  ? 319 ARG G NH1 1 
ATOM   4307 N NH2 . ARG C 2 80  ? 238.642 191.502 288.150 1.00 71.69  ? 319 ARG G NH2 1 
ATOM   4308 N N   . ARG C 2 81  ? 233.480 195.773 290.964 1.00 56.75  ? 320 ARG G N   1 
ATOM   4309 C CA  . ARG C 2 81  ? 232.392 196.705 291.236 1.00 57.72  ? 320 ARG G CA  1 
ATOM   4310 C C   . ARG C 2 81  ? 232.647 197.530 292.493 1.00 61.87  ? 320 ARG G C   1 
ATOM   4311 O O   . ARG C 2 81  ? 231.709 198.131 293.028 1.00 64.33  ? 320 ARG G O   1 
ATOM   4312 C CB  . ARG C 2 81  ? 231.059 195.965 291.356 1.00 55.32  ? 320 ARG G CB  1 
ATOM   4313 C CG  . ARG C 2 81  ? 229.902 196.678 290.682 1.00 54.62  ? 320 ARG G CG  1 
ATOM   4314 C CD  . ARG C 2 81  ? 228.857 195.702 290.171 1.00 49.25  ? 320 ARG G CD  1 
ATOM   4315 N NE  . ARG C 2 81  ? 229.449 194.621 289.395 1.00 52.75  ? 320 ARG G NE  1 
ATOM   4316 C CZ  . ARG C 2 81  ? 229.528 193.362 289.802 1.00 63.96  ? 320 ARG G CZ  1 
ATOM   4317 N NH1 . ARG C 2 81  ? 229.061 192.986 290.980 1.00 66.77  ? 320 ARG G NH1 1 
ATOM   4318 N NH2 . ARG C 2 81  ? 230.093 192.457 289.007 1.00 67.65  ? 320 ARG G NH2 1 
ATOM   4319 N N   . SER C 2 82  ? 233.888 197.574 292.972 1.00 68.88  ? 321 SER G N   1 
ATOM   4320 C CA  . SER C 2 82  ? 234.264 198.410 294.103 1.00 65.89  ? 321 SER G CA  1 
ATOM   4321 C C   . SER C 2 82  ? 235.778 198.548 294.102 1.00 67.59  ? 321 SER G C   1 
ATOM   4322 O O   . SER C 2 82  ? 236.490 197.580 293.825 1.00 72.62  ? 321 SER G O   1 
ATOM   4323 C CB  . SER C 2 82  ? 233.776 197.817 295.428 1.00 62.48  ? 321 SER G CB  1 
ATOM   4324 O OG  . SER C 2 82  ? 234.295 196.517 295.632 1.00 66.33  ? 321 SER G OG  1 
ATOM   4325 N N   . VAL C 2 83  ? 236.265 199.749 294.407 1.00 74.23  ? 322 VAL G N   1 
ATOM   4326 C CA  . VAL C 2 83  ? 237.687 200.049 294.301 1.00 80.00  ? 322 VAL G CA  1 
ATOM   4327 C C   . VAL C 2 83  ? 238.152 200.839 295.516 1.00 79.16  ? 322 VAL G C   1 
ATOM   4328 O O   . VAL C 2 83  ? 237.352 201.435 296.242 1.00 73.40  ? 322 VAL G O   1 
ATOM   4329 C CB  . VAL C 2 83  ? 238.008 200.826 293.008 1.00 83.87  ? 322 VAL G CB  1 
ATOM   4330 C CG1 . VAL C 2 83  ? 238.032 199.883 291.825 1.00 83.56  ? 322 VAL G CG1 1 
ATOM   4331 C CG2 . VAL C 2 83  ? 236.993 201.932 292.793 1.00 82.28  ? 322 VAL G CG2 1 
ATOM   4332 N N   . ARG C 2 84  ? 239.467 200.839 295.725 1.00 95.92  ? 323 ARG G N   1 
ATOM   4333 C CA  . ARG C 2 84  ? 240.091 201.617 296.783 1.00 92.99  ? 323 ARG G CA  1 
ATOM   4334 C C   . ARG C 2 84  ? 241.511 201.953 296.360 1.00 92.52  ? 323 ARG G C   1 
ATOM   4335 O O   . ARG C 2 84  ? 241.954 201.591 295.268 1.00 97.76  ? 323 ARG G O   1 
ATOM   4336 C CB  . ARG C 2 84  ? 240.092 200.863 298.116 1.00 99.51  ? 323 ARG G CB  1 
ATOM   4337 C CG  . ARG C 2 84  ? 239.003 201.308 299.068 1.00 97.63  ? 323 ARG G CG  1 
ATOM   4338 C CD  . ARG C 2 84  ? 238.960 200.455 300.325 1.00 94.97  ? 323 ARG G CD  1 
ATOM   4339 N NE  . ARG C 2 84  ? 238.306 199.174 300.096 1.00 91.06  ? 323 ARG G NE  1 
ATOM   4340 C CZ  . ARG C 2 84  ? 238.948 198.018 300.009 1.00 93.52  ? 323 ARG G CZ  1 
ATOM   4341 N NH1 . ARG C 2 84  ? 240.259 197.944 300.161 1.00 93.02  ? 323 ARG G NH1 1 
ATOM   4342 N NH2 . ARG C 2 84  ? 238.255 196.908 299.771 1.00 95.14  ? 323 ARG G NH2 1 
ATOM   4343 N N   . ARG C 2 85  ? 242.229 202.647 297.236 1.00 90.43  ? 324 ARG G N   1 
ATOM   4344 C CA  . ARG C 2 85  ? 243.625 202.992 296.992 1.00 95.65  ? 324 ARG G CA  1 
ATOM   4345 C C   . ARG C 2 85  ? 244.471 202.441 298.132 1.00 97.49  ? 324 ARG G C   1 
ATOM   4346 O O   . ARG C 2 85  ? 244.472 202.992 299.238 1.00 97.25  ? 324 ARG G O   1 
ATOM   4347 C CB  . ARG C 2 85  ? 243.802 204.502 296.852 1.00 97.05  ? 324 ARG G CB  1 
ATOM   4348 C CG  . ARG C 2 85  ? 245.253 204.945 296.769 1.00 96.23  ? 324 ARG G CG  1 
ATOM   4349 C CD  . ARG C 2 85  ? 245.380 206.229 295.973 1.00 93.90  ? 324 ARG G CD  1 
ATOM   4350 N NE  . ARG C 2 85  ? 245.672 207.378 296.821 1.00 96.90  ? 324 ARG G NE  1 
ATOM   4351 C CZ  . ARG C 2 85  ? 245.303 208.621 296.547 1.00 94.57  ? 324 ARG G CZ  1 
ATOM   4352 N NH1 . ARG C 2 85  ? 244.616 208.911 295.455 1.00 94.81  ? 324 ARG G NH1 1 
ATOM   4353 N NH2 . ARG C 2 85  ? 245.629 209.596 297.390 1.00 94.09  ? 324 ARG G NH2 1 
ATOM   4354 N N   . CYS C 2 86  ? 245.173 201.362 297.864 1.00 122.75 ? 325 CYS G N   1 
ATOM   4355 C CA  . CYS C 2 86  ? 246.061 200.693 298.796 1.00 127.02 ? 325 CYS G CA  1 
ATOM   4356 C C   . CYS C 2 86  ? 247.401 201.415 298.871 1.00 126.66 ? 325 CYS G C   1 
ATOM   4357 O O   . CYS C 2 86  ? 247.810 202.077 297.913 1.00 119.88 ? 325 CYS G O   1 
ATOM   4358 C CB  . CYS C 2 86  ? 246.285 199.241 298.370 1.00 126.66 ? 325 CYS G CB  1 
ATOM   4359 S SG  . CYS C 2 86  ? 246.688 199.060 296.627 1.00 130.17 ? 325 CYS G SG  1 
ATOM   4360 N N   . PRO C 2 87  ? 248.111 201.310 299.996 1.00 149.64 ? 326 PRO G N   1 
ATOM   4361 C CA  . PRO C 2 87  ? 249.409 202.008 300.133 1.00 149.66 ? 326 PRO G CA  1 
ATOM   4362 C C   . PRO C 2 87  ? 250.518 201.401 299.275 1.00 149.47 ? 326 PRO G C   1 
ATOM   4363 O O   . PRO C 2 87  ? 251.463 200.773 299.753 1.00 149.64 ? 326 PRO G O   1 
ATOM   4364 C CB  . PRO C 2 87  ? 249.710 201.873 301.629 1.00 149.35 ? 326 PRO G CB  1 
ATOM   4365 C CG  . PRO C 2 87  ? 248.412 201.486 302.276 1.00 148.19 ? 326 PRO G CG  1 
ATOM   4366 C CD  . PRO C 2 87  ? 247.689 200.680 301.256 1.00 148.63 ? 326 PRO G CD  1 
ATOM   4367 N N   . PHE C 2 88  ? 250.392 201.602 297.961 1.00 160.57 ? 327 PHE G N   1 
ATOM   4368 C CA  . PHE C 2 88  ? 251.407 201.203 296.985 1.00 162.83 ? 327 PHE G CA  1 
ATOM   4369 C C   . PHE C 2 88  ? 251.689 199.700 297.054 1.00 163.53 ? 327 PHE G C   1 
ATOM   4370 O O   . PHE C 2 88  ? 252.782 199.258 297.417 1.00 164.99 ? 327 PHE G O   1 
ATOM   4371 C CB  . PHE C 2 88  ? 252.692 202.018 297.173 1.00 163.56 ? 327 PHE G CB  1 
ATOM   4372 C CG  . PHE C 2 88  ? 252.543 203.471 296.824 1.00 163.75 ? 327 PHE G CG  1 
ATOM   4373 C CD1 . PHE C 2 88  ? 252.595 203.890 295.505 1.00 162.75 ? 327 PHE G CD1 1 
ATOM   4374 C CD2 . PHE C 2 88  ? 252.349 204.417 297.816 1.00 162.81 ? 327 PHE G CD2 1 
ATOM   4375 C CE1 . PHE C 2 88  ? 252.458 205.226 295.182 1.00 162.00 ? 327 PHE G CE1 1 
ATOM   4376 C CE2 . PHE C 2 88  ? 252.211 205.756 297.500 1.00 162.74 ? 327 PHE G CE2 1 
ATOM   4377 C CZ  . PHE C 2 88  ? 252.266 206.161 296.181 1.00 162.36 ? 327 PHE G CZ  1 
ATOM   4378 N N   . ARG C 2 89  ? 250.669 198.914 296.701 1.00 163.04 ? 328 ARG G N   1 
ATOM   4379 C CA  . ARG C 2 89  ? 250.808 197.461 296.702 1.00 163.62 ? 328 ARG G CA  1 
ATOM   4380 C C   . ARG C 2 89  ? 251.850 196.974 295.703 1.00 165.06 ? 328 ARG G C   1 
ATOM   4381 O O   . ARG C 2 89  ? 252.339 195.847 295.839 1.00 164.45 ? 328 ARG G O   1 
ATOM   4382 C CB  . ARG C 2 89  ? 249.463 196.800 296.400 1.00 162.41 ? 328 ARG G CB  1 
ATOM   4383 C CG  . ARG C 2 89  ? 248.981 196.993 294.970 1.00 161.55 ? 328 ARG G CG  1 
ATOM   4384 C CD  . ARG C 2 89  ? 247.671 196.262 294.725 1.00 160.79 ? 328 ARG G CD  1 
ATOM   4385 N NE  . ARG C 2 89  ? 247.051 196.661 293.468 1.00 161.13 ? 328 ARG G NE  1 
ATOM   4386 C CZ  . ARG C 2 89  ? 245.882 196.211 293.033 1.00 159.89 ? 328 ARG G CZ  1 
ATOM   4387 N NH1 . ARG C 2 89  ? 245.171 195.344 293.735 1.00 159.34 ? 328 ARG G NH1 1 
ATOM   4388 N NH2 . ARG C 2 89  ? 245.412 196.645 291.867 1.00 159.31 ? 328 ARG G NH2 1 
ATOM   4389 N N   . HIS C 2 90  ? 252.199 197.788 294.707 1.00 203.02 ? 329 HIS G N   1 
ATOM   4390 C CA  . HIS C 2 90  ? 253.181 197.420 293.695 1.00 204.24 ? 329 HIS G CA  1 
ATOM   4391 C C   . HIS C 2 90  ? 254.570 197.965 294.011 1.00 204.69 ? 329 HIS G C   1 
ATOM   4392 O O   . HIS C 2 90  ? 255.341 198.268 293.094 1.00 205.18 ? 329 HIS G O   1 
ATOM   4393 C CB  . HIS C 2 90  ? 252.723 197.892 292.316 1.00 203.79 ? 329 HIS G CB  1 
ATOM   4394 C CG  . HIS C 2 90  ? 251.510 197.179 291.807 1.00 204.30 ? 329 HIS G CG  1 
ATOM   4395 N ND1 . HIS C 2 90  ? 251.559 195.901 291.293 1.00 203.74 ? 329 HIS G ND1 1 
ATOM   4396 C CD2 . HIS C 2 90  ? 250.214 197.563 291.735 1.00 203.69 ? 329 HIS G CD2 1 
ATOM   4397 C CE1 . HIS C 2 90  ? 250.346 195.530 290.925 1.00 203.03 ? 329 HIS G CE1 1 
ATOM   4398 N NE2 . HIS C 2 90  ? 249.511 196.520 291.183 1.00 204.01 ? 329 HIS G NE2 1 
ATOM   4399 N N   . LEU C 2 91  ? 254.902 198.096 295.292 1.00 225.65 ? 330 LEU G N   1 
ATOM   4400 C CA  . LEU C 2 91  ? 256.230 198.542 295.707 1.00 226.07 ? 330 LEU G CA  1 
ATOM   4401 C C   . LEU C 2 91  ? 257.228 197.430 295.412 1.00 226.36 ? 330 LEU G C   1 
ATOM   4402 O O   . LEU C 2 91  ? 257.277 196.418 296.114 1.00 225.86 ? 330 LEU G O   1 
ATOM   4403 C CB  . LEU C 2 91  ? 256.231 198.911 297.186 1.00 226.43 ? 330 LEU G CB  1 
ATOM   4404 C CG  . LEU C 2 91  ? 257.555 199.424 297.756 1.00 226.47 ? 330 LEU G CG  1 
ATOM   4405 C CD1 . LEU C 2 91  ? 257.931 200.757 297.128 1.00 225.44 ? 330 LEU G CD1 1 
ATOM   4406 C CD2 . LEU C 2 91  ? 257.477 199.543 299.271 1.00 225.65 ? 330 LEU G CD2 1 
ATOM   4407 N N   . GLY C 2 92  ? 258.030 197.615 294.369 1.00 232.90 ? 331 GLY G N   1 
ATOM   4408 C CA  . GLY C 2 92  ? 258.955 196.598 293.923 1.00 232.63 ? 331 GLY G CA  1 
ATOM   4409 C C   . GLY C 2 92  ? 258.447 195.705 292.815 1.00 233.13 ? 331 GLY G C   1 
ATOM   4410 O O   . GLY C 2 92  ? 259.121 194.725 292.478 1.00 232.97 ? 331 GLY G O   1 
ATOM   4411 N N   . GLU C 2 93  ? 257.287 196.009 292.239 1.00 225.23 ? 332 GLU G N   1 
ATOM   4412 C CA  . GLU C 2 93  ? 256.707 195.224 291.161 1.00 224.09 ? 332 GLU G CA  1 
ATOM   4413 C C   . GLU C 2 93  ? 256.586 196.082 289.909 1.00 223.20 ? 332 GLU G C   1 
ATOM   4414 O O   . GLU C 2 93  ? 256.311 197.283 289.983 1.00 223.53 ? 332 GLU G O   1 
ATOM   4415 C CB  . GLU C 2 93  ? 255.328 194.675 291.549 1.00 223.51 ? 332 GLU G CB  1 
ATOM   4416 C CG  . GLU C 2 93  ? 255.352 193.696 292.711 1.00 223.28 ? 332 GLU G CG  1 
ATOM   4417 C CD  . GLU C 2 93  ? 253.965 193.225 293.102 1.00 222.92 ? 332 GLU G CD  1 
ATOM   4418 O OE1 . GLU C 2 93  ? 252.979 193.729 292.524 1.00 222.47 ? 332 GLU G OE1 1 
ATOM   4419 O OE2 . GLU C 2 93  ? 253.860 192.350 293.987 1.00 223.23 ? 332 GLU G OE2 1 
ATOM   4420 N N   . SER C 2 94  ? 256.793 195.453 288.756 1.00 197.42 ? 333 SER G N   1 
ATOM   4421 C CA  . SER C 2 94  ? 256.732 196.133 287.470 1.00 196.30 ? 333 SER G CA  1 
ATOM   4422 C C   . SER C 2 94  ? 255.408 195.822 286.788 1.00 195.07 ? 333 SER G C   1 
ATOM   4423 O O   . SER C 2 94  ? 255.078 194.653 286.562 1.00 193.99 ? 333 SER G O   1 
ATOM   4424 C CB  . SER C 2 94  ? 257.899 195.714 286.574 1.00 195.75 ? 333 SER G CB  1 
ATOM   4425 O OG  . SER C 2 94  ? 257.818 196.343 285.307 1.00 194.72 ? 333 SER G OG  1 
ATOM   4426 N N   . VAL C 2 95  ? 254.658 196.866 286.463 1.00 167.85 ? 334 VAL G N   1 
ATOM   4427 C CA  . VAL C 2 95  ? 253.375 196.746 285.786 1.00 166.14 ? 334 VAL G CA  1 
ATOM   4428 C C   . VAL C 2 95  ? 253.449 197.533 284.485 1.00 164.76 ? 334 VAL G C   1 
ATOM   4429 O O   . VAL C 2 95  ? 253.234 198.746 284.469 1.00 162.48 ? 334 VAL G O   1 
ATOM   4430 C CB  . VAL C 2 95  ? 252.218 197.245 286.671 1.00 163.61 ? 334 VAL G CB  1 
ATOM   4431 C CG1 . VAL C 2 95  ? 250.891 197.127 285.931 1.00 160.65 ? 334 VAL G CG1 1 
ATOM   4432 C CG2 . VAL C 2 95  ? 252.178 196.471 287.979 1.00 164.55 ? 334 VAL G CG2 1 
ATOM   4433 N N   . PRO C 2 96  ? 253.816 196.885 283.380 1.00 150.31 ? 335 PRO G N   1 
ATOM   4434 C CA  . PRO C 2 96  ? 253.706 197.525 282.069 1.00 147.06 ? 335 PRO G CA  1 
ATOM   4435 C C   . PRO C 2 96  ? 252.366 198.225 281.898 1.00 144.51 ? 335 PRO G C   1 
ATOM   4436 O O   . PRO C 2 96  ? 251.304 197.643 282.128 1.00 143.34 ? 335 PRO G O   1 
ATOM   4437 C CB  . PRO C 2 96  ? 253.844 196.339 281.109 1.00 147.66 ? 335 PRO G CB  1 
ATOM   4438 C CG  . PRO C 2 96  ? 254.634 195.270 281.928 1.00 148.46 ? 335 PRO G CG  1 
ATOM   4439 C CD  . PRO C 2 96  ? 254.852 195.845 283.317 1.00 149.34 ? 335 PRO G CD  1 
ATOM   4440 N N   . ASP C 2 97  ? 252.421 199.489 281.496 1.00 129.44 ? 336 ASP G N   1 
ATOM   4441 C CA  . ASP C 2 97  ? 251.232 200.318 281.371 1.00 130.40 ? 336 ASP G CA  1 
ATOM   4442 C C   . ASP C 2 97  ? 250.869 200.476 279.903 1.00 128.79 ? 336 ASP G C   1 
ATOM   4443 O O   . ASP C 2 97  ? 251.713 200.851 279.083 1.00 128.04 ? 336 ASP G O   1 
ATOM   4444 C CB  . ASP C 2 97  ? 251.453 201.687 282.015 1.00 134.44 ? 336 ASP G CB  1 
ATOM   4445 C CG  . ASP C 2 97  ? 251.518 201.614 283.527 1.00 135.36 ? 336 ASP G CG  1 
ATOM   4446 O OD1 . ASP C 2 97  ? 250.920 200.681 284.104 1.00 133.64 ? 336 ASP G OD1 1 
ATOM   4447 O OD2 . ASP C 2 97  ? 252.167 202.488 284.139 1.00 136.15 ? 336 ASP G OD2 1 
ATOM   4448 N N   . ASN C 2 98  ? 249.613 200.189 279.579 1.00 113.11 ? 337 ASN G N   1 
ATOM   4449 C CA  . ASN C 2 98  ? 249.139 200.310 278.216 1.00 112.87 ? 337 ASN G CA  1 
ATOM   4450 C C   . ASN C 2 98  ? 248.987 201.787 277.854 1.00 110.46 ? 337 ASN G C   1 
ATOM   4451 O O   . ASN C 2 98  ? 248.959 202.649 278.735 1.00 108.44 ? 337 ASN G O   1 
ATOM   4452 C CB  . ASN C 2 98  ? 247.811 199.575 278.061 1.00 114.98 ? 337 ASN G CB  1 
ATOM   4453 C CG  . ASN C 2 98  ? 246.622 200.468 278.312 1.00 115.40 ? 337 ASN G CG  1 
ATOM   4454 O OD1 . ASN C 2 98  ? 246.069 201.048 277.382 1.00 111.20 ? 337 ASN G OD1 1 
ATOM   4455 N ND2 . ASN C 2 98  ? 246.242 200.612 279.574 1.00 115.33 ? 337 ASN G ND2 1 
ATOM   4456 N N   . PRO C 2 99  ? 248.908 202.108 276.560 1.00 106.52 ? 338 PRO G N   1 
ATOM   4457 C CA  . PRO C 2 99  ? 248.787 203.522 276.166 1.00 109.75 ? 338 PRO G CA  1 
ATOM   4458 C C   . PRO C 2 99  ? 247.535 204.212 276.686 1.00 109.13 ? 338 PRO G C   1 
ATOM   4459 O O   . PRO C 2 99  ? 247.517 205.448 276.751 1.00 109.84 ? 338 PRO G O   1 
ATOM   4460 C CB  . PRO C 2 99  ? 248.791 203.459 274.633 1.00 107.84 ? 338 PRO G CB  1 
ATOM   4461 C CG  . PRO C 2 99  ? 249.499 202.193 274.310 1.00 105.67 ? 338 PRO G CG  1 
ATOM   4462 C CD  . PRO C 2 99  ? 249.122 201.232 275.394 1.00 102.18 ? 338 PRO G CD  1 
ATOM   4463 N N   . GLU C 2 100 ? 246.494 203.471 277.057 1.00 94.48  ? 339 GLU G N   1 
ATOM   4464 C CA  . GLU C 2 100 ? 245.221 204.057 277.477 1.00 90.59  ? 339 GLU G CA  1 
ATOM   4465 C C   . GLU C 2 100 ? 245.024 204.002 278.987 1.00 92.06  ? 339 GLU G C   1 
ATOM   4466 O O   . GLU C 2 100 ? 243.911 203.769 279.463 1.00 96.14  ? 339 GLU G O   1 
ATOM   4467 C CB  . GLU C 2 100 ? 244.063 203.368 276.762 1.00 90.04  ? 339 GLU G CB  1 
ATOM   4468 C CG  . GLU C 2 100 ? 243.885 203.792 275.313 1.00 94.75  ? 339 GLU G CG  1 
ATOM   4469 C CD  . GLU C 2 100 ? 244.891 203.141 274.381 1.00 96.89  ? 339 GLU G CD  1 
ATOM   4470 O OE1 . GLU C 2 100 ? 245.711 202.328 274.855 1.00 95.03  ? 339 GLU G OE1 1 
ATOM   4471 O OE2 . GLU C 2 100 ? 244.860 203.446 273.171 1.00 97.89  ? 339 GLU G OE2 1 
ATOM   4472 N N   . ARG C 2 101 ? 246.081 204.210 279.764 1.00 92.88  ? 340 ARG G N   1 
ATOM   4473 C CA  . ARG C 2 101 ? 246.008 204.192 281.217 1.00 94.90  ? 340 ARG G CA  1 
ATOM   4474 C C   . ARG C 2 101 ? 246.443 205.537 281.781 1.00 96.25  ? 340 ARG G C   1 
ATOM   4475 O O   . ARG C 2 101 ? 247.409 206.137 281.301 1.00 97.26  ? 340 ARG G O   1 
ATOM   4476 C CB  . ARG C 2 101 ? 246.889 203.081 281.796 1.00 95.23  ? 340 ARG G CB  1 
ATOM   4477 C CG  . ARG C 2 101 ? 246.911 203.030 283.316 1.00 94.04  ? 340 ARG G CG  1 
ATOM   4478 C CD  . ARG C 2 101 ? 248.063 202.181 283.825 1.00 94.68  ? 340 ARG G CD  1 
ATOM   4479 N NE  . ARG C 2 101 ? 247.867 200.763 283.554 1.00 97.57  ? 340 ARG G NE  1 
ATOM   4480 C CZ  . ARG C 2 101 ? 247.609 199.854 284.484 1.00 98.28  ? 340 ARG G CZ  1 
ATOM   4481 N NH1 . ARG C 2 101 ? 247.529 200.178 285.763 1.00 100.78 ? 340 ARG G NH1 1 
ATOM   4482 N NH2 . ARG C 2 101 ? 247.427 198.588 284.120 1.00 93.00  ? 340 ARG G NH2 1 
ATOM   4483 N N   . PHE C 2 102 ? 245.723 206.010 282.796 1.00 89.72  ? 341 PHE G N   1 
ATOM   4484 C CA  . PHE C 2 102 ? 246.121 207.228 283.487 1.00 86.25  ? 341 PHE G CA  1 
ATOM   4485 C C   . PHE C 2 102 ? 247.425 206.998 284.244 1.00 93.43  ? 341 PHE G C   1 
ATOM   4486 O O   . PHE C 2 102 ? 247.725 205.885 284.684 1.00 99.77  ? 341 PHE G O   1 
ATOM   4487 C CB  . PHE C 2 102 ? 245.032 207.685 284.459 1.00 83.13  ? 341 PHE G CB  1 
ATOM   4488 C CG  . PHE C 2 102 ? 243.728 208.047 283.800 1.00 83.45  ? 341 PHE G CG  1 
ATOM   4489 C CD1 . PHE C 2 102 ? 243.621 208.143 282.425 1.00 86.95  ? 341 PHE G CD1 1 
ATOM   4490 C CD2 . PHE C 2 102 ? 242.607 208.300 284.566 1.00 87.26  ? 341 PHE G CD2 1 
ATOM   4491 C CE1 . PHE C 2 102 ? 242.420 208.476 281.833 1.00 88.09  ? 341 PHE G CE1 1 
ATOM   4492 C CE2 . PHE C 2 102 ? 241.406 208.635 283.977 1.00 85.63  ? 341 PHE G CE2 1 
ATOM   4493 C CZ  . PHE C 2 102 ? 241.314 208.724 282.610 1.00 85.72  ? 341 PHE G CZ  1 
ATOM   4494 N N   . ASP C 2 103 ? 248.204 208.062 284.395 1.00 99.40  ? 342 ASP G N   1 
ATOM   4495 C CA  . ASP C 2 103 ? 249.533 207.949 284.986 1.00 100.37 ? 342 ASP G CA  1 
ATOM   4496 C C   . ASP C 2 103 ? 249.713 208.762 286.256 1.00 101.90 ? 342 ASP G C   1 
ATOM   4497 O O   . ASP C 2 103 ? 250.337 208.278 287.203 1.00 104.14 ? 342 ASP G O   1 
ATOM   4498 C CB  . ASP C 2 103 ? 250.593 208.364 283.961 1.00 100.36 ? 342 ASP G CB  1 
ATOM   4499 C CG  . ASP C 2 103 ? 250.258 207.893 282.565 1.00 104.98 ? 342 ASP G CG  1 
ATOM   4500 O OD1 . ASP C 2 103 ? 250.114 206.668 282.368 1.00 104.20 ? 342 ASP G OD1 1 
ATOM   4501 O OD2 . ASP C 2 103 ? 250.126 208.748 281.667 1.00 105.65 ? 342 ASP G OD2 1 
ATOM   4502 N N   . SER C 2 104 ? 249.196 209.990 286.305 1.00 101.63 ? 343 SER G N   1 
ATOM   4503 C CA  . SER C 2 104 ? 249.314 210.821 287.494 1.00 102.45 ? 343 SER G CA  1 
ATOM   4504 C C   . SER C 2 104 ? 247.986 211.089 288.184 1.00 99.68  ? 343 SER G C   1 
ATOM   4505 O O   . SER C 2 104 ? 247.983 211.655 289.281 1.00 94.70  ? 343 SER G O   1 
ATOM   4506 C CB  . SER C 2 104 ? 249.970 212.164 287.145 1.00 104.77 ? 343 SER G CB  1 
ATOM   4507 O OG  . SER C 2 104 ? 249.500 212.644 285.900 1.00 107.39 ? 343 SER G OG  1 
ATOM   4508 N N   . GLN C 2 105 ? 246.870 210.700 287.576 1.00 105.34 ? 344 GLN G N   1 
ATOM   4509 C CA  . GLN C 2 105 ? 245.561 210.912 288.167 1.00 105.36 ? 344 GLN G CA  1 
ATOM   4510 C C   . GLN C 2 105 ? 245.008 209.586 288.661 1.00 107.90 ? 344 GLN G C   1 
ATOM   4511 O O   . GLN C 2 105 ? 244.769 208.683 287.842 1.00 109.05 ? 344 GLN G O   1 
ATOM   4512 C CB  . GLN C 2 105 ? 244.617 211.539 287.150 1.00 103.98 ? 344 GLN G CB  1 
ATOM   4513 C CG  . GLN C 2 105 ? 244.973 212.967 286.779 1.00 105.75 ? 344 GLN G CG  1 
ATOM   4514 C CD  . GLN C 2 105 ? 244.971 213.895 287.977 1.00 110.28 ? 344 GLN G CD  1 
ATOM   4515 O OE1 . GLN C 2 105 ? 243.914 214.322 288.444 1.00 110.84 ? 344 GLN G OE1 1 
ATOM   4516 N NE2 . GLN C 2 105 ? 246.157 214.213 288.483 1.00 111.31 ? 344 GLN G NE2 1 
ATOM   4517 N N   . PRO C 2 106 ? 244.793 209.414 289.967 1.00 93.01  ? 345 PRO G N   1 
ATOM   4518 C CA  . PRO C 2 106 ? 244.324 208.118 290.480 1.00 93.03  ? 345 PRO G CA  1 
ATOM   4519 C C   . PRO C 2 106 ? 242.863 207.848 290.164 1.00 94.06  ? 345 PRO G C   1 
ATOM   4520 O O   . PRO C 2 106 ? 242.013 207.894 291.059 1.00 90.10  ? 345 PRO G O   1 
ATOM   4521 C CB  . PRO C 2 106 ? 244.551 208.245 291.990 1.00 93.92  ? 345 PRO G CB  1 
ATOM   4522 C CG  . PRO C 2 106 ? 244.449 209.711 292.250 1.00 92.70  ? 345 PRO G CG  1 
ATOM   4523 C CD  . PRO C 2 106 ? 245.046 210.382 291.047 1.00 86.71  ? 345 PRO G CD  1 
ATOM   4524 N N   . CYS C 2 107 ? 242.557 207.542 288.907 1.00 83.21  ? 346 CYS G N   1 
ATOM   4525 C CA  . CYS C 2 107 ? 241.180 207.395 288.470 1.00 76.54  ? 346 CYS G CA  1 
ATOM   4526 C C   . CYS C 2 107 ? 240.962 206.039 287.814 1.00 81.47  ? 346 CYS G C   1 
ATOM   4527 O O   . CYS C 2 107 ? 241.902 205.313 287.482 1.00 77.96  ? 346 CYS G O   1 
ATOM   4528 C CB  . CYS C 2 107 ? 240.782 208.506 287.498 1.00 80.07  ? 346 CYS G CB  1 
ATOM   4529 S SG  . CYS C 2 107 ? 241.603 210.080 287.774 1.00 96.42  ? 346 CYS G SG  1 
ATOM   4530 N N   . VAL C 2 108 ? 239.682 205.717 287.639 1.00 77.50  ? 347 VAL G N   1 
ATOM   4531 C CA  . VAL C 2 108 ? 239.245 204.493 286.984 1.00 70.99  ? 347 VAL G CA  1 
ATOM   4532 C C   . VAL C 2 108 ? 238.012 204.821 286.154 1.00 69.34  ? 347 VAL G C   1 
ATOM   4533 O O   . VAL C 2 108 ? 237.179 205.649 286.540 1.00 73.62  ? 347 VAL G O   1 
ATOM   4534 C CB  . VAL C 2 108 ? 238.973 203.366 288.010 1.00 71.76  ? 347 VAL G CB  1 
ATOM   4535 C CG1 . VAL C 2 108 ? 237.833 203.742 288.942 1.00 68.05  ? 347 VAL G CG1 1 
ATOM   4536 C CG2 . VAL C 2 108 ? 238.686 202.051 287.304 1.00 74.03  ? 347 VAL G CG2 1 
ATOM   4537 N N   . LEU C 2 109 ? 237.910 204.179 284.993 1.00 59.82  ? 348 LEU G N   1 
ATOM   4538 C CA  . LEU C 2 109 ? 236.865 204.466 284.022 1.00 61.35  ? 348 LEU G CA  1 
ATOM   4539 C C   . LEU C 2 109 ? 235.925 203.278 283.892 1.00 69.00  ? 348 LEU G C   1 
ATOM   4540 O O   . LEU C 2 109 ? 236.370 202.134 283.759 1.00 74.65  ? 348 LEU G O   1 
ATOM   4541 C CB  . LEU C 2 109 ? 237.460 204.792 282.650 1.00 66.50  ? 348 LEU G CB  1 
ATOM   4542 C CG  . LEU C 2 109 ? 238.408 205.985 282.556 1.00 75.60  ? 348 LEU G CG  1 
ATOM   4543 C CD1 . LEU C 2 109 ? 239.847 205.533 282.735 1.00 78.65  ? 348 LEU G CD1 1 
ATOM   4544 C CD2 . LEU C 2 109 ? 238.233 206.693 281.227 1.00 75.54  ? 348 LEU G CD2 1 
ATOM   4545 N N   . GLY C 2 110 ? 234.624 203.555 283.932 1.00 62.74  ? 349 GLY G N   1 
ATOM   4546 C CA  . GLY C 2 110 ? 233.644 202.520 283.645 1.00 64.06  ? 349 GLY G CA  1 
ATOM   4547 C C   . GLY C 2 110 ? 233.767 202.062 282.203 1.00 64.37  ? 349 GLY G C   1 
ATOM   4548 O O   . GLY C 2 110 ? 233.776 202.879 281.275 1.00 72.45  ? 349 GLY G O   1 
ATOM   4549 N N   . ARG C 2 111 ? 233.862 200.746 282.006 1.00 48.93  ? 350 ARG G N   1 
ATOM   4550 C CA  . ARG C 2 111 ? 234.137 200.211 280.679 1.00 53.41  ? 350 ARG G CA  1 
ATOM   4551 C C   . ARG C 2 111 ? 232.974 200.376 279.711 1.00 63.67  ? 350 ARG G C   1 
ATOM   4552 O O   . ARG C 2 111 ? 233.193 200.313 278.497 1.00 75.64  ? 350 ARG G O   1 
ATOM   4553 C CB  . ARG C 2 111 ? 234.516 198.733 280.775 1.00 53.65  ? 350 ARG G CB  1 
ATOM   4554 C CG  . ARG C 2 111 ? 233.324 197.807 280.902 1.00 60.33  ? 350 ARG G CG  1 
ATOM   4555 C CD  . ARG C 2 111 ? 233.645 196.396 280.457 1.00 55.27  ? 350 ARG G CD  1 
ATOM   4556 N NE  . ARG C 2 111 ? 232.725 195.438 281.056 1.00 54.42  ? 350 ARG G NE  1 
ATOM   4557 C CZ  . ARG C 2 111 ? 232.485 194.226 280.578 1.00 61.24  ? 350 ARG G CZ  1 
ATOM   4558 N NH1 . ARG C 2 111 ? 233.087 193.783 279.486 1.00 65.53  ? 350 ARG G NH1 1 
ATOM   4559 N NH2 . ARG C 2 111 ? 231.620 193.439 281.210 1.00 59.03  ? 350 ARG G NH2 1 
ATOM   4560 N N   . GLU C 2 112 ? 231.756 200.586 280.203 1.00 47.59  ? 351 GLU G N   1 
ATOM   4561 C CA  . GLU C 2 112 ? 230.596 200.724 279.334 1.00 49.31  ? 351 GLU G CA  1 
ATOM   4562 C C   . GLU C 2 112 ? 230.525 202.145 278.789 1.00 56.45  ? 351 GLU G C   1 
ATOM   4563 O O   . GLU C 2 112 ? 230.666 203.113 279.542 1.00 63.35  ? 351 GLU G O   1 
ATOM   4564 C CB  . GLU C 2 112 ? 229.312 200.378 280.087 1.00 47.20  ? 351 GLU G CB  1 
ATOM   4565 C CG  . GLU C 2 112 ? 228.058 200.856 279.388 1.00 54.98  ? 351 GLU G CG  1 
ATOM   4566 C CD  . GLU C 2 112 ? 226.905 199.891 279.533 1.00 59.36  ? 351 GLU G CD  1 
ATOM   4567 O OE1 . GLU C 2 112 ? 226.995 198.976 280.377 1.00 56.60  ? 351 GLU G OE1 1 
ATOM   4568 O OE2 . GLU C 2 112 ? 225.907 200.049 278.801 1.00 59.91  ? 351 GLU G OE2 1 
ATOM   4569 N N   . SER C 2 113 ? 230.307 202.265 277.482 1.00 53.28  ? 352 SER G N   1 
ATOM   4570 C CA  . SER C 2 113 ? 230.248 203.554 276.803 1.00 51.13  ? 352 SER G CA  1 
ATOM   4571 C C   . SER C 2 113 ? 228.834 203.788 276.289 1.00 49.97  ? 352 SER G C   1 
ATOM   4572 O O   . SER C 2 113 ? 228.288 202.953 275.561 1.00 51.94  ? 352 SER G O   1 
ATOM   4573 C CB  . SER C 2 113 ? 231.253 203.612 275.655 1.00 52.60  ? 352 SER G CB  1 
ATOM   4574 O OG  . SER C 2 113 ? 232.517 203.125 276.066 1.00 55.67  ? 352 SER G OG  1 
ATOM   4575 N N   . PHE C 2 114 ? 228.253 204.923 276.660 1.00 46.52  ? 353 PHE G N   1 
ATOM   4576 C CA  . PHE C 2 114 ? 226.911 205.296 276.242 1.00 44.16  ? 353 PHE G CA  1 
ATOM   4577 C C   . PHE C 2 114 ? 226.984 206.306 275.106 1.00 54.06  ? 353 PHE G C   1 
ATOM   4578 O O   . PHE C 2 114 ? 227.892 207.141 275.062 1.00 62.98  ? 353 PHE G O   1 
ATOM   4579 C CB  . PHE C 2 114 ? 226.117 205.889 277.409 1.00 45.17  ? 353 PHE G CB  1 
ATOM   4580 C CG  . PHE C 2 114 ? 226.480 205.314 278.746 1.00 44.96  ? 353 PHE G CG  1 
ATOM   4581 C CD1 . PHE C 2 114 ? 225.903 204.139 279.189 1.00 42.35  ? 353 PHE G CD1 1 
ATOM   4582 C CD2 . PHE C 2 114 ? 227.394 205.951 279.563 1.00 49.72  ? 353 PHE G CD2 1 
ATOM   4583 C CE1 . PHE C 2 114 ? 226.233 203.611 280.419 1.00 40.18  ? 353 PHE G CE1 1 
ATOM   4584 C CE2 . PHE C 2 114 ? 227.728 205.424 280.793 1.00 52.42  ? 353 PHE G CE2 1 
ATOM   4585 C CZ  . PHE C 2 114 ? 227.148 204.253 281.220 1.00 42.57  ? 353 PHE G CZ  1 
ATOM   4586 N N   . ALA C 2 115 ? 226.025 206.227 274.187 1.00 47.47  ? 354 ALA G N   1 
ATOM   4587 C CA  . ALA C 2 115 ? 225.949 207.160 273.075 1.00 42.27  ? 354 ALA G CA  1 
ATOM   4588 C C   . ALA C 2 115 ? 224.554 207.726 272.858 1.00 45.85  ? 354 ALA G C   1 
ATOM   4589 O O   . ALA C 2 115 ? 224.357 208.489 271.907 1.00 51.51  ? 354 ALA G O   1 
ATOM   4590 C CB  . ALA C 2 115 ? 226.433 206.492 271.781 1.00 48.27  ? 354 ALA G CB  1 
ATOM   4591 N N   . SER C 2 116 ? 223.590 207.379 273.703 1.00 43.92  ? 355 SER G N   1 
ATOM   4592 C CA  . SER C 2 116 ? 222.234 207.914 273.625 1.00 48.12  ? 355 SER G CA  1 
ATOM   4593 C C   . SER C 2 116 ? 221.491 207.483 274.883 1.00 48.29  ? 355 SER G C   1 
ATOM   4594 O O   . SER C 2 116 ? 222.044 206.802 275.752 1.00 50.74  ? 355 SER G O   1 
ATOM   4595 C CB  . SER C 2 116 ? 221.506 207.441 272.366 1.00 40.07  ? 355 SER G CB  1 
ATOM   4596 O OG  . SER C 2 116 ? 220.175 207.921 272.339 1.00 44.66  ? 355 SER G OG  1 
ATOM   4597 N N   . GLY C 2 117 ? 220.232 207.895 274.978 1.00 41.93  ? 356 GLY G N   1 
ATOM   4598 C CA  . GLY C 2 117 ? 219.366 207.441 276.048 1.00 38.50  ? 356 GLY G CA  1 
ATOM   4599 C C   . GLY C 2 117 ? 219.713 208.062 277.389 1.00 39.96  ? 356 GLY G C   1 
ATOM   4600 O O   . GLY C 2 117 ? 220.708 208.763 277.557 1.00 50.36  ? 356 GLY G O   1 
ATOM   4601 N N   . LYS C 2 118 ? 218.856 207.782 278.365 1.00 43.95  ? 357 LYS G N   1 
ATOM   4602 C CA  . LYS C 2 118 ? 219.023 208.265 279.729 1.00 48.01  ? 357 LYS G CA  1 
ATOM   4603 C C   . LYS C 2 118 ? 219.517 207.120 280.600 1.00 52.80  ? 357 LYS G C   1 
ATOM   4604 O O   . LYS C 2 118 ? 218.907 206.046 280.625 1.00 53.86  ? 357 LYS G O   1 
ATOM   4605 C CB  . LYS C 2 118 ? 217.713 208.828 280.277 1.00 49.31  ? 357 LYS G CB  1 
ATOM   4606 C CG  . LYS C 2 118 ? 216.760 209.348 279.225 1.00 42.04  ? 357 LYS G CG  1 
ATOM   4607 C CD  . LYS C 2 118 ? 215.685 210.193 279.875 1.00 42.23  ? 357 LYS G CD  1 
ATOM   4608 C CE  . LYS C 2 118 ? 214.366 210.074 279.149 1.00 49.62  ? 357 LYS G CE  1 
ATOM   4609 N NZ  . LYS C 2 118 ? 213.414 211.117 279.609 1.00 50.89  ? 357 LYS G NZ  1 
ATOM   4610 N N   . HIS C 2 119 ? 220.612 207.353 281.316 1.00 42.36  ? 358 HIS G N   1 
ATOM   4611 C CA  . HIS C 2 119 ? 221.234 206.340 282.153 1.00 38.23  ? 358 HIS G CA  1 
ATOM   4612 C C   . HIS C 2 119 ? 221.541 206.936 283.517 1.00 37.78  ? 358 HIS G C   1 
ATOM   4613 O O   . HIS C 2 119 ? 221.531 208.156 283.685 1.00 50.73  ? 358 HIS G O   1 
ATOM   4614 C CB  . HIS C 2 119 ? 222.521 205.803 281.515 1.00 42.33  ? 358 HIS G CB  1 
ATOM   4615 C CG  . HIS C 2 119 ? 222.378 205.446 280.069 1.00 44.51  ? 358 HIS G CG  1 
ATOM   4616 N ND1 . HIS C 2 119 ? 222.384 204.143 279.620 1.00 38.74  ? 358 HIS G ND1 1 
ATOM   4617 C CD2 . HIS C 2 119 ? 222.231 206.220 278.968 1.00 40.20  ? 358 HIS G CD2 1 
ATOM   4618 C CE1 . HIS C 2 119 ? 222.244 204.130 278.307 1.00 31.18  ? 358 HIS G CE1 1 
ATOM   4619 N NE2 . HIS C 2 119 ? 222.147 205.378 277.887 1.00 39.13  ? 358 HIS G NE2 1 
ATOM   4620 N N   . TYR C 2 120 ? 221.790 206.073 284.499 1.00 34.53  ? 359 TYR G N   1 
ATOM   4621 C CA  . TYR C 2 120 ? 222.223 206.560 285.801 1.00 43.00  ? 359 TYR G CA  1 
ATOM   4622 C C   . TYR C 2 120 ? 222.812 205.411 286.603 1.00 40.45  ? 359 TYR G C   1 
ATOM   4623 O O   . TYR C 2 120 ? 222.355 204.269 286.510 1.00 47.09  ? 359 TYR G O   1 
ATOM   4624 C CB  . TYR C 2 120 ? 221.078 207.238 286.572 1.00 47.66  ? 359 TYR G CB  1 
ATOM   4625 C CG  . TYR C 2 120 ? 220.103 206.323 287.282 1.00 42.08  ? 359 TYR G CG  1 
ATOM   4626 C CD1 . TYR C 2 120 ? 220.349 205.876 288.574 1.00 41.19  ? 359 TYR G CD1 1 
ATOM   4627 C CD2 . TYR C 2 120 ? 218.914 205.945 286.678 1.00 39.00  ? 359 TYR G CD2 1 
ATOM   4628 C CE1 . TYR C 2 120 ? 219.454 205.058 289.230 1.00 41.41  ? 359 TYR G CE1 1 
ATOM   4629 C CE2 . TYR C 2 120 ? 218.012 205.128 287.328 1.00 43.55  ? 359 TYR G CE2 1 
ATOM   4630 C CZ  . TYR C 2 120 ? 218.288 204.688 288.604 1.00 45.24  ? 359 TYR G CZ  1 
ATOM   4631 O OH  . TYR C 2 120 ? 217.395 203.872 289.255 1.00 49.23  ? 359 TYR G OH  1 
ATOM   4632 N N   . TRP C 2 121 ? 223.833 205.734 287.393 1.00 41.88  ? 360 TRP G N   1 
ATOM   4633 C CA  . TRP C 2 121 ? 224.489 204.751 288.244 1.00 41.54  ? 360 TRP G CA  1 
ATOM   4634 C C   . TRP C 2 121 ? 224.739 205.334 289.627 1.00 48.99  ? 360 TRP G C   1 
ATOM   4635 O O   . TRP C 2 121 ? 225.084 206.509 289.764 1.00 47.84  ? 360 TRP G O   1 
ATOM   4636 C CB  . TRP C 2 121 ? 225.809 204.257 287.636 1.00 39.29  ? 360 TRP G CB  1 
ATOM   4637 C CG  . TRP C 2 121 ? 226.772 205.332 287.235 1.00 37.87  ? 360 TRP G CG  1 
ATOM   4638 C CD1 . TRP C 2 121 ? 227.855 205.764 287.940 1.00 37.87  ? 360 TRP G CD1 1 
ATOM   4639 C CD2 . TRP C 2 121 ? 226.763 206.084 286.015 1.00 46.77  ? 360 TRP G CD2 1 
ATOM   4640 N NE1 . TRP C 2 121 ? 228.511 206.750 287.245 1.00 42.35  ? 360 TRP G NE1 1 
ATOM   4641 C CE2 . TRP C 2 121 ? 227.860 206.963 286.059 1.00 50.36  ? 360 TRP G CE2 1 
ATOM   4642 C CE3 . TRP C 2 121 ? 225.927 206.105 284.895 1.00 47.27  ? 360 TRP G CE3 1 
ATOM   4643 C CZ2 . TRP C 2 121 ? 228.144 207.852 285.027 1.00 48.99  ? 360 TRP G CZ2 1 
ATOM   4644 C CZ3 . TRP C 2 121 ? 226.211 206.987 283.872 1.00 36.11  ? 360 TRP G CZ3 1 
ATOM   4645 C CH2 . TRP C 2 121 ? 227.308 207.849 283.945 1.00 39.52  ? 360 TRP G CH2 1 
ATOM   4646 N N   . GLU C 2 122 ? 224.566 204.501 290.646 1.00 53.26  ? 361 GLU G N   1 
ATOM   4647 C CA  . GLU C 2 122 ? 224.746 204.896 292.033 1.00 48.06  ? 361 GLU G CA  1 
ATOM   4648 C C   . GLU C 2 122 ? 226.143 204.534 292.517 1.00 51.87  ? 361 GLU G C   1 
ATOM   4649 O O   . GLU C 2 122 ? 226.736 203.546 292.077 1.00 63.90  ? 361 GLU G O   1 
ATOM   4650 C CB  . GLU C 2 122 ? 223.705 204.224 292.929 1.00 51.06  ? 361 GLU G CB  1 
ATOM   4651 C CG  . GLU C 2 122 ? 222.392 204.964 293.021 1.00 47.10  ? 361 GLU G CG  1 
ATOM   4652 C CD  . GLU C 2 122 ? 221.307 204.339 292.177 1.00 54.73  ? 361 GLU G CD  1 
ATOM   4653 O OE1 . GLU C 2 122 ? 221.633 203.492 291.321 1.00 58.03  ? 361 GLU G OE1 1 
ATOM   4654 O OE2 . GLU C 2 122 ? 220.127 204.688 292.375 1.00 58.62  ? 361 GLU G OE2 1 
ATOM   4655 N N   . VAL C 2 123 ? 226.668 205.349 293.429 1.00 44.47  ? 362 VAL G N   1 
ATOM   4656 C CA  . VAL C 2 123 ? 227.959 205.108 294.059 1.00 50.93  ? 362 VAL G CA  1 
ATOM   4657 C C   . VAL C 2 123 ? 227.793 205.267 295.563 1.00 58.87  ? 362 VAL G C   1 
ATOM   4658 O O   . VAL C 2 123 ? 227.217 206.257 296.027 1.00 62.45  ? 362 VAL G O   1 
ATOM   4659 C CB  . VAL C 2 123 ? 229.045 206.065 293.532 1.00 52.67  ? 362 VAL G CB  1 
ATOM   4660 C CG1 . VAL C 2 123 ? 230.399 205.696 294.103 1.00 52.30  ? 362 VAL G CG1 1 
ATOM   4661 C CG2 . VAL C 2 123 ? 229.089 206.040 292.018 1.00 57.18  ? 362 VAL G CG2 1 
ATOM   4662 N N   . GLU C 2 124 ? 228.293 204.294 296.319 1.00 67.03  ? 363 GLU G N   1 
ATOM   4663 C CA  . GLU C 2 124 ? 228.323 204.375 297.772 1.00 66.46  ? 363 GLU G CA  1 
ATOM   4664 C C   . GLU C 2 124 ? 229.731 204.744 298.223 1.00 79.13  ? 363 GLU G C   1 
ATOM   4665 O O   . GLU C 2 124 ? 230.660 203.942 298.088 1.00 70.49  ? 363 GLU G O   1 
ATOM   4666 C CB  . GLU C 2 124 ? 227.891 203.049 298.398 1.00 69.46  ? 363 GLU G CB  1 
ATOM   4667 C CG  . GLU C 2 124 ? 226.603 202.482 297.818 1.00 77.39  ? 363 GLU G CG  1 
ATOM   4668 C CD  . GLU C 2 124 ? 226.489 200.976 297.981 1.00 81.07  ? 363 GLU G CD  1 
ATOM   4669 O OE1 . GLU C 2 124 ? 227.193 200.414 298.846 1.00 83.45  ? 363 GLU G OE1 1 
ATOM   4670 O OE2 . GLU C 2 124 ? 225.688 200.356 297.249 1.00 70.07  ? 363 GLU G OE2 1 
ATOM   4671 N N   . VAL C 2 125 ? 229.881 205.953 298.764 1.00 87.45  ? 364 VAL G N   1 
ATOM   4672 C CA  . VAL C 2 125 ? 231.193 206.512 299.078 1.00 75.70  ? 364 VAL G CA  1 
ATOM   4673 C C   . VAL C 2 125 ? 231.318 206.774 300.572 1.00 71.41  ? 364 VAL G C   1 
ATOM   4674 O O   . VAL C 2 125 ? 231.966 207.741 300.988 1.00 74.05  ? 364 VAL G O   1 
ATOM   4675 C CB  . VAL C 2 125 ? 231.452 207.803 298.284 1.00 75.12  ? 364 VAL G CB  1 
ATOM   4676 C CG1 . VAL C 2 125 ? 231.931 207.474 296.884 1.00 80.89  ? 364 VAL G CG1 1 
ATOM   4677 C CG2 . VAL C 2 125 ? 230.194 208.650 298.237 1.00 75.24  ? 364 VAL G CG2 1 
ATOM   4678 N N   . GLU C 2 126 ? 230.689 205.929 301.384 1.00 75.56  ? 365 GLU G N   1 
ATOM   4679 C CA  . GLU C 2 126 ? 230.744 206.103 302.828 1.00 74.61  ? 365 GLU G CA  1 
ATOM   4680 C C   . GLU C 2 126 ? 232.180 206.051 303.334 1.00 78.73  ? 365 GLU G C   1 
ATOM   4681 O O   . GLU C 2 126 ? 232.986 205.231 302.887 1.00 83.15  ? 365 GLU G O   1 
ATOM   4682 C CB  . GLU C 2 126 ? 229.916 205.025 303.523 1.00 79.60  ? 365 GLU G CB  1 
ATOM   4683 C CG  . GLU C 2 126 ? 229.014 205.564 304.609 1.00 80.98  ? 365 GLU G CG  1 
ATOM   4684 C CD  . GLU C 2 126 ? 227.920 206.439 304.051 1.00 78.23  ? 365 GLU G CD  1 
ATOM   4685 O OE1 . GLU C 2 126 ? 227.090 205.921 303.278 1.00 73.28  ? 365 GLU G OE1 1 
ATOM   4686 O OE2 . GLU C 2 126 ? 227.901 207.645 304.372 1.00 82.23  ? 365 GLU G OE2 1 
ATOM   4687 N N   . ASN C 2 127 ? 232.494 206.946 304.272 1.00 77.99  ? 366 ASN G N   1 
ATOM   4688 C CA  . ASN C 2 127 ? 233.773 206.943 304.983 1.00 81.64  ? 366 ASN G CA  1 
ATOM   4689 C C   . ASN C 2 127 ? 234.957 207.096 304.031 1.00 83.15  ? 366 ASN G C   1 
ATOM   4690 O O   . ASN C 2 127 ? 235.824 206.225 303.943 1.00 83.08  ? 366 ASN G O   1 
ATOM   4691 C CB  . ASN C 2 127 ? 233.920 205.682 305.835 1.00 85.25  ? 366 ASN G CB  1 
ATOM   4692 C CG  . ASN C 2 127 ? 232.664 205.360 306.612 1.00 84.45  ? 366 ASN G CG  1 
ATOM   4693 O OD1 . ASN C 2 127 ? 231.675 206.089 306.541 1.00 81.18  ? 366 ASN G OD1 1 
ATOM   4694 N ND2 . ASN C 2 127 ? 232.693 204.264 307.361 1.00 85.40  ? 366 ASN G ND2 1 
ATOM   4695 N N   . VAL C 2 128 ? 234.991 208.213 303.309 1.00 77.08  ? 367 VAL G N   1 
ATOM   4696 C CA  . VAL C 2 128 ? 236.108 208.579 302.446 1.00 79.33  ? 367 VAL G CA  1 
ATOM   4697 C C   . VAL C 2 128 ? 236.440 210.035 302.747 1.00 80.89  ? 367 VAL G C   1 
ATOM   4698 O O   . VAL C 2 128 ? 235.589 210.767 303.263 1.00 78.48  ? 367 VAL G O   1 
ATOM   4699 C CB  . VAL C 2 128 ? 235.762 208.378 300.956 1.00 79.28  ? 367 VAL G CB  1 
ATOM   4700 C CG1 . VAL C 2 128 ? 236.940 208.725 300.052 1.00 78.29  ? 367 VAL G CG1 1 
ATOM   4701 C CG2 . VAL C 2 128 ? 235.297 206.954 300.704 1.00 78.58  ? 367 VAL G CG2 1 
ATOM   4702 N N   . ILE C 2 129 ? 237.676 210.450 302.462 1.00 84.92  ? 368 ILE G N   1 
ATOM   4703 C CA  . ILE C 2 129 ? 238.056 211.845 302.660 1.00 89.46  ? 368 ILE G CA  1 
ATOM   4704 C C   . ILE C 2 129 ? 238.181 212.616 301.349 1.00 91.28  ? 368 ILE G C   1 
ATOM   4705 O O   . ILE C 2 129 ? 238.072 213.851 301.362 1.00 89.57  ? 368 ILE G O   1 
ATOM   4706 C CB  . ILE C 2 129 ? 239.371 211.969 303.457 1.00 90.25  ? 368 ILE G CB  1 
ATOM   4707 C CG1 . ILE C 2 129 ? 240.550 211.451 302.634 1.00 88.75  ? 368 ILE G CG1 1 
ATOM   4708 C CG2 . ILE C 2 129 ? 239.265 211.217 304.774 1.00 88.03  ? 368 ILE G CG2 1 
ATOM   4709 C CD1 . ILE C 2 129 ? 241.857 211.408 303.399 1.00 89.66  ? 368 ILE G CD1 1 
ATOM   4710 N N   . GLU C 2 130 ? 238.401 211.934 300.224 1.00 88.25  ? 369 GLU G N   1 
ATOM   4711 C CA  . GLU C 2 130 ? 238.597 212.597 298.934 1.00 81.64  ? 369 GLU G CA  1 
ATOM   4712 C C   . GLU C 2 130 ? 238.012 211.698 297.849 1.00 79.30  ? 369 GLU G C   1 
ATOM   4713 O O   . GLU C 2 130 ? 238.620 210.687 297.485 1.00 85.71  ? 369 GLU G O   1 
ATOM   4714 C CB  . GLU C 2 130 ? 240.074 212.871 298.677 1.00 82.88  ? 369 GLU G CB  1 
ATOM   4715 C CG  . GLU C 2 130 ? 240.667 214.003 299.497 1.00 87.76  ? 369 GLU G CG  1 
ATOM   4716 C CD  . GLU C 2 130 ? 240.010 215.335 299.216 1.00 94.67  ? 369 GLU G CD  1 
ATOM   4717 O OE1 . GLU C 2 130 ? 239.647 215.585 298.047 1.00 94.20  ? 369 GLU G OE1 1 
ATOM   4718 O OE2 . GLU C 2 130 ? 239.857 216.134 300.164 1.00 95.14  ? 369 GLU G OE2 1 
ATOM   4719 N N   . TRP C 2 131 ? 236.840 212.061 297.335 1.00 61.39  ? 370 TRP G N   1 
ATOM   4720 C CA  . TRP C 2 131 ? 236.241 211.318 296.237 1.00 69.79  ? 370 TRP G CA  1 
ATOM   4721 C C   . TRP C 2 131 ? 235.689 212.280 295.196 1.00 80.79  ? 370 TRP G C   1 
ATOM   4722 O O   . TRP C 2 131 ? 235.095 213.312 295.526 1.00 84.15  ? 370 TRP G O   1 
ATOM   4723 C CB  . TRP C 2 131 ? 235.131 210.370 296.718 1.00 67.64  ? 370 TRP G CB  1 
ATOM   4724 C CG  . TRP C 2 131 ? 233.988 211.034 297.417 1.00 66.76  ? 370 TRP G CG  1 
ATOM   4725 C CD1 . TRP C 2 131 ? 233.829 211.180 298.761 1.00 74.57  ? 370 TRP G CD1 1 
ATOM   4726 C CD2 . TRP C 2 131 ? 232.827 211.612 296.811 1.00 66.09  ? 370 TRP G CD2 1 
ATOM   4727 N NE1 . TRP C 2 131 ? 232.649 211.826 299.031 1.00 74.11  ? 370 TRP G NE1 1 
ATOM   4728 C CE2 . TRP C 2 131 ? 232.014 212.102 297.850 1.00 69.71  ? 370 TRP G CE2 1 
ATOM   4729 C CE3 . TRP C 2 131 ? 232.399 211.770 295.491 1.00 69.20  ? 370 TRP G CE3 1 
ATOM   4730 C CZ2 . TRP C 2 131 ? 230.801 212.738 297.610 1.00 72.06  ? 370 TRP G CZ2 1 
ATOM   4731 C CZ3 . TRP C 2 131 ? 231.196 212.401 295.256 1.00 73.09  ? 370 TRP G CZ3 1 
ATOM   4732 C CH2 . TRP C 2 131 ? 230.411 212.877 296.309 1.00 75.80  ? 370 TRP G CH2 1 
ATOM   4733 N N   . THR C 2 132 ? 235.906 211.927 293.927 1.00 74.13  ? 371 THR G N   1 
ATOM   4734 C CA  . THR C 2 132 ? 235.344 212.656 292.796 1.00 69.54  ? 371 THR G CA  1 
ATOM   4735 C C   . THR C 2 132 ? 234.637 211.646 291.909 1.00 61.74  ? 371 THR G C   1 
ATOM   4736 O O   . THR C 2 132 ? 235.226 210.623 291.551 1.00 50.87  ? 371 THR G O   1 
ATOM   4737 C CB  . THR C 2 132 ? 236.426 213.386 291.995 1.00 66.47  ? 371 THR G CB  1 
ATOM   4738 O OG1 . THR C 2 132 ? 236.943 212.507 290.992 1.00 68.45  ? 371 THR G OG1 1 
ATOM   4739 C CG2 . THR C 2 132 ? 237.566 213.795 292.898 1.00 64.01  ? 371 THR G CG2 1 
ATOM   4740 N N   . VAL C 2 133 ? 233.386 211.922 291.553 1.00 61.69  ? 372 VAL G N   1 
ATOM   4741 C CA  . VAL C 2 133 ? 232.629 211.005 290.707 1.00 59.72  ? 372 VAL G CA  1 
ATOM   4742 C C   . VAL C 2 133 ? 231.982 211.784 289.574 1.00 62.92  ? 372 VAL G C   1 
ATOM   4743 O O   . VAL C 2 133 ? 231.571 212.936 289.746 1.00 66.26  ? 372 VAL G O   1 
ATOM   4744 C CB  . VAL C 2 133 ? 231.562 210.214 291.500 1.00 58.43  ? 372 VAL G CB  1 
ATOM   4745 C CG1 . VAL C 2 133 ? 232.200 209.454 292.650 1.00 67.48  ? 372 VAL G CG1 1 
ATOM   4746 C CG2 . VAL C 2 133 ? 230.470 211.137 292.008 1.00 58.69  ? 372 VAL G CG2 1 
ATOM   4747 N N   . GLY C 2 134 ? 231.892 211.158 288.406 1.00 60.27  ? 373 GLY G N   1 
ATOM   4748 C CA  . GLY C 2 134 ? 231.190 211.811 287.319 1.00 57.57  ? 373 GLY G CA  1 
ATOM   4749 C C   . GLY C 2 134 ? 231.394 211.090 285.999 1.00 52.93  ? 373 GLY G C   1 
ATOM   4750 O O   . GLY C 2 134 ? 231.559 209.874 285.955 1.00 54.03  ? 373 GLY G O   1 
ATOM   4751 N N   . VAL C 2 135 ? 231.372 211.885 284.934 1.00 51.23  ? 374 VAL G N   1 
ATOM   4752 C CA  . VAL C 2 135 ? 231.363 211.402 283.560 1.00 51.62  ? 374 VAL G CA  1 
ATOM   4753 C C   . VAL C 2 135 ? 232.551 212.010 282.829 1.00 52.23  ? 374 VAL G C   1 
ATOM   4754 O O   . VAL C 2 135 ? 232.888 213.181 283.044 1.00 59.36  ? 374 VAL G O   1 
ATOM   4755 C CB  . VAL C 2 135 ? 230.045 211.761 282.850 1.00 51.24  ? 374 VAL G CB  1 
ATOM   4756 C CG1 . VAL C 2 135 ? 230.035 211.217 281.437 1.00 49.62  ? 374 VAL G CG1 1 
ATOM   4757 C CG2 . VAL C 2 135 ? 228.856 211.241 283.640 1.00 50.10  ? 374 VAL G CG2 1 
ATOM   4758 N N   . CYS C 2 136 ? 233.192 211.215 281.979 1.00 57.96  ? 375 CYS G N   1 
ATOM   4759 C CA  . CYS C 2 136 ? 234.279 211.689 281.141 1.00 55.50  ? 375 CYS G CA  1 
ATOM   4760 C C   . CYS C 2 136 ? 234.077 211.200 279.716 1.00 65.16  ? 375 CYS G C   1 
ATOM   4761 O O   . CYS C 2 136 ? 233.507 210.131 279.480 1.00 79.58  ? 375 CYS G O   1 
ATOM   4762 C CB  . CYS C 2 136 ? 235.637 211.215 281.666 1.00 54.47  ? 375 CYS G CB  1 
ATOM   4763 S SG  . CYS C 2 136 ? 236.069 209.529 281.208 1.00 72.04  ? 375 CYS G SG  1 
ATOM   4764 N N   . ARG C 2 137 ? 234.544 211.996 278.761 1.00 49.03  ? 376 ARG G N   1 
ATOM   4765 C CA  . ARG C 2 137 ? 234.515 211.557 277.379 1.00 49.57  ? 376 ARG G CA  1 
ATOM   4766 C C   . ARG C 2 137 ? 235.494 210.403 277.185 1.00 59.93  ? 376 ARG G C   1 
ATOM   4767 O O   . ARG C 2 137 ? 236.414 210.191 277.978 1.00 67.35  ? 376 ARG G O   1 
ATOM   4768 C CB  . ARG C 2 137 ? 234.860 212.714 276.445 1.00 49.89  ? 376 ARG G CB  1 
ATOM   4769 C CG  . ARG C 2 137 ? 233.730 213.695 276.238 1.00 52.51  ? 376 ARG G CG  1 
ATOM   4770 C CD  . ARG C 2 137 ? 234.238 214.968 275.595 1.00 51.76  ? 376 ARG G CD  1 
ATOM   4771 N NE  . ARG C 2 137 ? 233.208 215.624 274.802 1.00 44.70  ? 376 ARG G NE  1 
ATOM   4772 C CZ  . ARG C 2 137 ? 233.264 216.887 274.405 1.00 48.28  ? 376 ARG G CZ  1 
ATOM   4773 N NH1 . ARG C 2 137 ? 234.290 217.662 274.712 1.00 48.45  ? 376 ARG G NH1 1 
ATOM   4774 N NH2 . ARG C 2 137 ? 232.266 217.383 273.680 1.00 58.47  ? 376 ARG G NH2 1 
ATOM   4775 N N   . ASP C 2 138 ? 235.283 209.632 276.123 1.00 59.43  ? 377 ASP G N   1 
ATOM   4776 C CA  . ASP C 2 138 ? 236.247 208.588 275.807 1.00 60.61  ? 377 ASP G CA  1 
ATOM   4777 C C   . ASP C 2 138 ? 237.553 209.147 275.260 1.00 63.32  ? 377 ASP G C   1 
ATOM   4778 O O   . ASP C 2 138 ? 238.524 208.395 275.133 1.00 58.32  ? 377 ASP G O   1 
ATOM   4779 C CB  . ASP C 2 138 ? 235.648 207.595 274.811 1.00 60.25  ? 377 ASP G CB  1 
ATOM   4780 C CG  . ASP C 2 138 ? 234.835 208.271 273.735 1.00 64.44  ? 377 ASP G CG  1 
ATOM   4781 O OD1 . ASP C 2 138 ? 234.710 209.512 273.775 1.00 65.71  ? 377 ASP G OD1 1 
ATOM   4782 O OD2 . ASP C 2 138 ? 234.320 207.561 272.849 1.00 65.99  ? 377 ASP G OD2 1 
ATOM   4783 N N   . SER C 2 139 ? 237.603 210.442 274.955 1.00 74.09  ? 378 SER G N   1 
ATOM   4784 C CA  . SER C 2 139 ? 238.758 211.079 274.334 1.00 76.18  ? 378 SER G CA  1 
ATOM   4785 C C   . SER C 2 139 ? 239.393 212.118 275.252 1.00 79.63  ? 378 SER G C   1 
ATOM   4786 O O   . SER C 2 139 ? 239.757 213.211 274.818 1.00 80.03  ? 378 SER G O   1 
ATOM   4787 C CB  . SER C 2 139 ? 238.369 211.722 273.007 1.00 73.92  ? 378 SER G CB  1 
ATOM   4788 O OG  . SER C 2 139 ? 237.893 213.042 273.207 1.00 74.07  ? 378 SER G OG  1 
ATOM   4789 N N   . VAL C 2 140 ? 239.520 211.796 276.532 1.00 77.37  ? 379 VAL G N   1 
ATOM   4790 C CA  . VAL C 2 140 ? 240.227 212.659 277.464 1.00 70.77  ? 379 VAL G CA  1 
ATOM   4791 C C   . VAL C 2 140 ? 241.700 212.276 277.488 1.00 75.95  ? 379 VAL G C   1 
ATOM   4792 O O   . VAL C 2 140 ? 242.101 211.194 277.052 1.00 79.59  ? 379 VAL G O   1 
ATOM   4793 C CB  . VAL C 2 140 ? 239.622 212.602 278.878 1.00 73.89  ? 379 VAL G CB  1 
ATOM   4794 C CG1 . VAL C 2 140 ? 238.110 212.641 278.808 1.00 80.07  ? 379 VAL G CG1 1 
ATOM   4795 C CG2 . VAL C 2 140 ? 240.099 211.352 279.603 1.00 74.57  ? 379 VAL G CG2 1 
ATOM   4796 N N   . GLU C 2 141 ? 242.516 213.188 278.005 1.00 90.27  ? 380 GLU G N   1 
ATOM   4797 C CA  . GLU C 2 141 ? 243.953 212.980 278.072 1.00 91.56  ? 380 GLU G CA  1 
ATOM   4798 C C   . GLU C 2 141 ? 244.284 211.833 279.019 1.00 87.35  ? 380 GLU G C   1 
ATOM   4799 O O   . GLU C 2 141 ? 243.567 211.568 279.987 1.00 86.21  ? 380 GLU G O   1 
ATOM   4800 C CB  . GLU C 2 141 ? 244.643 214.273 278.521 1.00 92.05  ? 380 GLU G CB  1 
ATOM   4801 C CG  . GLU C 2 141 ? 246.105 214.147 278.927 1.00 92.61  ? 380 GLU G CG  1 
ATOM   4802 C CD  . GLU C 2 141 ? 246.278 213.688 280.362 1.00 95.87  ? 380 GLU G CD  1 
ATOM   4803 O OE1 . GLU C 2 141 ? 245.288 213.709 281.119 1.00 95.34  ? 380 GLU G OE1 1 
ATOM   4804 O OE2 . GLU C 2 141 ? 247.399 213.297 280.731 1.00 99.16  ? 380 GLU G OE2 1 
ATOM   4805 N N   . ARG C 2 142 ? 245.377 211.149 278.728 1.00 86.32  ? 381 ARG G N   1 
ATOM   4806 C CA  . ARG C 2 142 ? 245.885 210.088 279.587 1.00 90.54  ? 381 ARG G CA  1 
ATOM   4807 C C   . ARG C 2 142 ? 247.349 210.273 279.958 1.00 90.10  ? 381 ARG G C   1 
ATOM   4808 O O   . ARG C 2 142 ? 247.730 209.976 281.091 1.00 90.25  ? 381 ARG G O   1 
ATOM   4809 C CB  . ARG C 2 142 ? 245.683 208.733 278.896 1.00 92.82  ? 381 ARG G CB  1 
ATOM   4810 C CG  . ARG C 2 142 ? 244.247 208.244 278.921 1.00 90.37  ? 381 ARG G CG  1 
ATOM   4811 C CD  . ARG C 2 142 ? 243.829 207.664 277.583 1.00 91.02  ? 381 ARG G CD  1 
ATOM   4812 N NE  . ARG C 2 142 ? 243.059 206.436 277.736 1.00 95.85  ? 381 ARG G NE  1 
ATOM   4813 C CZ  . ARG C 2 142 ? 241.750 206.389 277.943 1.00 94.06  ? 381 ARG G CZ  1 
ATOM   4814 N NH1 . ARG C 2 142 ? 241.024 207.491 278.032 1.00 92.26  ? 381 ARG G NH1 1 
ATOM   4815 N NH2 . ARG C 2 142 ? 241.155 205.206 278.063 1.00 90.28  ? 381 ARG G NH2 1 
ATOM   4816 N N   . LYS C 2 143 ? 248.172 210.771 279.037 1.00 91.40  ? 382 LYS G N   1 
ATOM   4817 C CA  . LYS C 2 143 ? 249.620 210.882 279.226 1.00 90.12  ? 382 LYS G CA  1 
ATOM   4818 C C   . LYS C 2 143 ? 249.937 212.202 279.916 1.00 89.24  ? 382 LYS G C   1 
ATOM   4819 O O   . LYS C 2 143 ? 250.163 213.227 279.273 1.00 92.95  ? 382 LYS G O   1 
ATOM   4820 C CB  . LYS C 2 143 ? 250.338 210.772 277.883 1.00 96.99  ? 382 LYS G CB  1 
ATOM   4821 C CG  . LYS C 2 143 ? 250.865 209.380 277.454 1.00 97.20  ? 382 LYS G CG  1 
ATOM   4822 C CD  . LYS C 2 143 ? 251.484 208.453 278.527 1.00 94.93  ? 382 LYS G CD  1 
ATOM   4823 C CE  . LYS C 2 143 ? 252.365 209.158 279.562 1.00 96.06  ? 382 LYS G CE  1 
ATOM   4824 N NZ  . LYS C 2 143 ? 252.784 208.237 280.654 1.00 97.44  ? 382 LYS G NZ  1 
ATOM   4825 N N   . GLY C 2 144 ? 249.952 212.179 281.241 1.00 101.63 ? 383 GLY G N   1 
ATOM   4826 C CA  . GLY C 2 144 ? 250.290 213.345 282.031 1.00 106.50 ? 383 GLY G CA  1 
ATOM   4827 C C   . GLY C 2 144 ? 249.227 213.658 283.069 1.00 109.23 ? 383 GLY G C   1 
ATOM   4828 O O   . GLY C 2 144 ? 248.421 212.809 283.461 1.00 111.32 ? 383 GLY G O   1 
ATOM   4829 N N   . GLU C 2 145 ? 249.239 214.910 283.517 1.00 96.07  ? 384 GLU G N   1 
ATOM   4830 C CA  . GLU C 2 145 ? 248.300 215.399 284.519 1.00 93.92  ? 384 GLU G CA  1 
ATOM   4831 C C   . GLU C 2 145 ? 247.515 216.577 283.958 1.00 91.81  ? 384 GLU G C   1 
ATOM   4832 O O   . GLU C 2 145 ? 248.104 217.528 283.435 1.00 91.61  ? 384 GLU G O   1 
ATOM   4833 C CB  . GLU C 2 145 ? 249.035 215.812 285.794 1.00 89.55  ? 384 GLU G CB  1 
ATOM   4834 C CG  . GLU C 2 145 ? 248.219 216.686 286.728 1.00 91.27  ? 384 GLU G CG  1 
ATOM   4835 C CD  . GLU C 2 145 ? 248.534 218.158 286.567 1.00 98.20  ? 384 GLU G CD  1 
ATOM   4836 O OE1 . GLU C 2 145 ? 249.702 218.487 286.274 1.00 101.51 ? 384 GLU G OE1 1 
ATOM   4837 O OE2 . GLU C 2 145 ? 247.613 218.985 286.729 1.00 99.44  ? 384 GLU G OE2 1 
ATOM   4838 N N   . VAL C 2 146 ? 246.191 216.514 284.075 1.00 88.51  ? 385 VAL G N   1 
ATOM   4839 C CA  . VAL C 2 146 ? 245.301 217.560 283.602 1.00 89.15  ? 385 VAL G CA  1 
ATOM   4840 C C   . VAL C 2 146 ? 244.349 217.941 284.729 1.00 88.34  ? 385 VAL G C   1 
ATOM   4841 O O   . VAL C 2 146 ? 244.458 217.459 285.855 1.00 90.42  ? 385 VAL G O   1 
ATOM   4842 C CB  . VAL C 2 146 ? 244.513 217.140 282.346 1.00 90.78  ? 385 VAL G CB  1 
ATOM   4843 C CG1 . VAL C 2 146 ? 245.454 216.919 281.178 1.00 89.96  ? 385 VAL G CG1 1 
ATOM   4844 C CG2 . VAL C 2 146 ? 243.687 215.898 282.635 1.00 86.87  ? 385 VAL G CG2 1 
ATOM   4845 N N   . LEU C 2 147 ? 243.408 218.822 284.408 1.00 80.58  ? 386 LEU G N   1 
ATOM   4846 C CA  . LEU C 2 147 ? 242.403 219.266 285.359 1.00 81.63  ? 386 LEU G CA  1 
ATOM   4847 C C   . LEU C 2 147 ? 241.034 218.714 284.980 1.00 80.81  ? 386 LEU G C   1 
ATOM   4848 O O   . LEU C 2 147 ? 240.673 218.641 283.803 1.00 76.97  ? 386 LEU G O   1 
ATOM   4849 C CB  . LEU C 2 147 ? 242.344 220.794 285.428 1.00 84.30  ? 386 LEU G CB  1 
ATOM   4850 C CG  . LEU C 2 147 ? 243.615 221.645 285.518 1.00 88.25  ? 386 LEU G CG  1 
ATOM   4851 C CD1 . LEU C 2 147 ? 243.288 222.972 286.178 1.00 87.98  ? 386 LEU G CD1 1 
ATOM   4852 C CD2 . LEU C 2 147 ? 244.716 220.947 286.305 1.00 84.35  ? 386 LEU G CD2 1 
ATOM   4853 N N   . LEU C 2 148 ? 240.272 218.329 285.999 1.00 85.93  ? 387 LEU G N   1 
ATOM   4854 C CA  . LEU C 2 148 ? 238.947 217.740 285.813 1.00 86.41  ? 387 LEU G CA  1 
ATOM   4855 C C   . LEU C 2 148 ? 237.949 218.880 285.655 1.00 88.59  ? 387 LEU G C   1 
ATOM   4856 O O   . LEU C 2 148 ? 237.417 219.410 286.631 1.00 95.89  ? 387 LEU G O   1 
ATOM   4857 C CB  . LEU C 2 148 ? 238.590 216.834 286.985 1.00 85.87  ? 387 LEU G CB  1 
ATOM   4858 C CG  . LEU C 2 148 ? 239.431 215.572 287.220 1.00 88.13  ? 387 LEU G CG  1 
ATOM   4859 C CD1 . LEU C 2 148 ? 239.679 214.825 285.919 1.00 87.55  ? 387 LEU G CD1 1 
ATOM   4860 C CD2 . LEU C 2 148 ? 240.745 215.875 287.934 1.00 86.46  ? 387 LEU G CD2 1 
ATOM   4861 N N   . ILE C 2 149 ? 237.690 219.261 284.407 1.00 63.65  ? 388 ILE G N   1 
ATOM   4862 C CA  . ILE C 2 149 ? 236.846 220.412 284.097 1.00 55.23  ? 388 ILE G CA  1 
ATOM   4863 C C   . ILE C 2 149 ? 235.926 220.070 282.931 1.00 67.07  ? 388 ILE G C   1 
ATOM   4864 O O   . ILE C 2 149 ? 236.243 219.169 282.141 1.00 79.97  ? 388 ILE G O   1 
ATOM   4865 C CB  . ILE C 2 149 ? 237.704 221.647 283.783 1.00 57.27  ? 388 ILE G CB  1 
ATOM   4866 C CG1 . ILE C 2 149 ? 238.860 221.261 282.860 1.00 59.16  ? 388 ILE G CG1 1 
ATOM   4867 C CG2 . ILE C 2 149 ? 238.225 222.276 285.062 1.00 64.19  ? 388 ILE G CG2 1 
ATOM   4868 C CD1 . ILE C 2 149 ? 239.835 222.383 282.601 1.00 66.43  ? 388 ILE G CD1 1 
ATOM   4869 N N   . PRO C 2 150 ? 234.782 220.746 282.783 1.00 60.34  ? 389 PRO G N   1 
ATOM   4870 C CA  . PRO C 2 150 ? 233.915 220.474 281.625 1.00 58.54  ? 389 PRO G CA  1 
ATOM   4871 C C   . PRO C 2 150 ? 234.563 220.779 280.287 1.00 58.21  ? 389 PRO G C   1 
ATOM   4872 O O   . PRO C 2 150 ? 234.139 220.217 279.271 1.00 50.72  ? 389 PRO G O   1 
ATOM   4873 C CB  . PRO C 2 150 ? 232.699 221.377 281.873 1.00 53.51  ? 389 PRO G CB  1 
ATOM   4874 C CG  . PRO C 2 150 ? 232.712 221.645 283.331 1.00 56.50  ? 389 PRO G CG  1 
ATOM   4875 C CD  . PRO C 2 150 ? 234.157 221.684 283.728 1.00 59.75  ? 389 PRO G CD  1 
ATOM   4876 N N   . GLN C 2 151 ? 235.566 221.656 280.247 1.00 66.07  ? 390 GLN G N   1 
ATOM   4877 C CA  . GLN C 2 151 ? 236.240 221.946 278.986 1.00 65.29  ? 390 GLN G CA  1 
ATOM   4878 C C   . GLN C 2 151 ? 237.035 220.741 278.502 1.00 61.06  ? 390 GLN G C   1 
ATOM   4879 O O   . GLN C 2 151 ? 236.942 220.351 277.333 1.00 67.58  ? 390 GLN G O   1 
ATOM   4880 C CB  . GLN C 2 151 ? 237.149 223.164 279.144 1.00 65.55  ? 390 GLN G CB  1 
ATOM   4881 C CG  . GLN C 2 151 ? 236.434 224.489 278.984 1.00 62.68  ? 390 GLN G CG  1 
ATOM   4882 C CD  . GLN C 2 151 ? 236.655 225.406 280.162 1.00 64.91  ? 390 GLN G CD  1 
ATOM   4883 O OE1 . GLN C 2 151 ? 237.719 225.398 280.777 1.00 67.37  ? 390 GLN G OE1 1 
ATOM   4884 N NE2 . GLN C 2 151 ? 235.647 226.205 280.487 1.00 66.03  ? 390 GLN G NE2 1 
ATOM   4885 N N   . ASN C 2 152 ? 237.820 220.134 279.392 1.00 57.03  ? 391 ASN G N   1 
ATOM   4886 C CA  . ASN C 2 152 ? 238.606 218.964 279.026 1.00 67.89  ? 391 ASN G CA  1 
ATOM   4887 C C   . ASN C 2 152 ? 237.763 217.706 278.874 1.00 74.08  ? 391 ASN G C   1 
ATOM   4888 O O   . ASN C 2 152 ? 238.292 216.680 278.434 1.00 76.16  ? 391 ASN G O   1 
ATOM   4889 C CB  . ASN C 2 152 ? 239.704 218.725 280.062 1.00 66.60  ? 391 ASN G CB  1 
ATOM   4890 C CG  . ASN C 2 152 ? 241.087 218.757 279.456 1.00 66.40  ? 391 ASN G CG  1 
ATOM   4891 O OD1 . ASN C 2 152 ? 241.242 218.895 278.244 1.00 66.91  ? 391 ASN G OD1 1 
ATOM   4892 N ND2 . ASN C 2 152 ? 242.104 218.629 280.297 1.00 68.63  ? 391 ASN G ND2 1 
ATOM   4893 N N   . GLY C 2 153 ? 236.480 217.753 279.221 1.00 68.48  ? 392 GLY G N   1 
ATOM   4894 C CA  . GLY C 2 153 ? 235.650 216.568 279.163 1.00 66.66  ? 392 GLY G CA  1 
ATOM   4895 C C   . GLY C 2 153 ? 235.600 215.829 280.483 1.00 62.24  ? 392 GLY G C   1 
ATOM   4896 O O   . GLY C 2 153 ? 235.895 214.632 280.547 1.00 68.53  ? 392 GLY G O   1 
ATOM   4897 N N   . PHE C 2 154 ? 235.232 216.539 281.550 1.00 57.45  ? 393 PHE G N   1 
ATOM   4898 C CA  . PHE C 2 154 ? 235.180 215.975 282.900 1.00 60.97  ? 393 PHE G CA  1 
ATOM   4899 C C   . PHE C 2 154 ? 234.044 216.666 283.653 1.00 66.67  ? 393 PHE G C   1 
ATOM   4900 O O   . PHE C 2 154 ? 234.232 217.751 284.209 1.00 71.03  ? 393 PHE G O   1 
ATOM   4901 C CB  . PHE C 2 154 ? 236.509 216.160 283.617 1.00 65.86  ? 393 PHE G CB  1 
ATOM   4902 C CG  . PHE C 2 154 ? 237.591 215.229 283.157 1.00 60.35  ? 393 PHE G CG  1 
ATOM   4903 C CD1 . PHE C 2 154 ? 237.422 213.860 283.219 1.00 66.85  ? 393 PHE G CD1 1 
ATOM   4904 C CD2 . PHE C 2 154 ? 238.785 215.728 282.669 1.00 61.51  ? 393 PHE G CD2 1 
ATOM   4905 C CE1 . PHE C 2 154 ? 238.424 213.007 282.803 1.00 70.70  ? 393 PHE G CE1 1 
ATOM   4906 C CE2 . PHE C 2 154 ? 239.788 214.879 282.253 1.00 63.03  ? 393 PHE G CE2 1 
ATOM   4907 C CZ  . PHE C 2 154 ? 239.606 213.519 282.320 1.00 66.11  ? 393 PHE G CZ  1 
ATOM   4908 N N   . TRP C 2 155 ? 232.871 216.039 283.673 1.00 52.97  ? 394 TRP G N   1 
ATOM   4909 C CA  . TRP C 2 155 ? 231.757 216.519 284.484 1.00 53.48  ? 394 TRP G CA  1 
ATOM   4910 C C   . TRP C 2 155 ? 231.816 215.787 285.818 1.00 52.88  ? 394 TRP G C   1 
ATOM   4911 O O   . TRP C 2 155 ? 231.460 214.608 285.896 1.00 63.35  ? 394 TRP G O   1 
ATOM   4912 C CB  . TRP C 2 155 ? 230.422 216.274 283.789 1.00 53.65  ? 394 TRP G CB  1 
ATOM   4913 C CG  . TRP C 2 155 ? 230.222 217.020 282.509 1.00 53.89  ? 394 TRP G CG  1 
ATOM   4914 C CD1 . TRP C 2 155 ? 229.399 218.087 282.307 1.00 51.29  ? 394 TRP G CD1 1 
ATOM   4915 C CD2 . TRP C 2 155 ? 230.829 216.736 281.244 1.00 54.14  ? 394 TRP G CD2 1 
ATOM   4916 N NE1 . TRP C 2 155 ? 229.465 218.495 280.999 1.00 48.50  ? 394 TRP G NE1 1 
ATOM   4917 C CE2 . TRP C 2 155 ? 230.336 217.680 280.325 1.00 56.03  ? 394 TRP G CE2 1 
ATOM   4918 C CE3 . TRP C 2 155 ? 231.744 215.779 280.800 1.00 51.16  ? 394 TRP G CE3 1 
ATOM   4919 C CZ2 . TRP C 2 155 ? 230.729 217.697 278.991 1.00 58.87  ? 394 TRP G CZ2 1 
ATOM   4920 C CZ3 . TRP C 2 155 ? 232.133 215.798 279.477 1.00 53.40  ? 394 TRP G CZ3 1 
ATOM   4921 C CH2 . TRP C 2 155 ? 231.627 216.749 278.588 1.00 55.30  ? 394 TRP G CH2 1 
ATOM   4922 N N   . THR C 2 156 ? 232.263 216.473 286.868 1.00 56.84  ? 395 THR G N   1 
ATOM   4923 C CA  . THR C 2 156 ? 232.571 215.799 288.120 1.00 59.90  ? 395 THR G CA  1 
ATOM   4924 C C   . THR C 2 156 ? 231.969 216.537 289.305 1.00 58.68  ? 395 THR G C   1 
ATOM   4925 O O   . THR C 2 156 ? 231.848 217.764 289.304 1.00 62.96  ? 395 THR G O   1 
ATOM   4926 C CB  . THR C 2 156 ? 234.083 215.669 288.328 1.00 66.86  ? 395 THR G CB  1 
ATOM   4927 O OG1 . THR C 2 156 ? 234.719 216.909 288.001 1.00 71.71  ? 395 THR G OG1 1 
ATOM   4928 C CG2 . THR C 2 156 ? 234.645 214.574 287.444 1.00 67.25  ? 395 THR G CG2 1 
ATOM   4929 N N   . LEU C 2 157 ? 231.591 215.762 290.317 1.00 57.41  ? 396 LEU G N   1 
ATOM   4930 C CA  . LEU C 2 157 ? 231.248 216.265 291.639 1.00 59.62  ? 396 LEU G CA  1 
ATOM   4931 C C   . LEU C 2 157 ? 232.329 215.802 292.602 1.00 62.28  ? 396 LEU G C   1 
ATOM   4932 O O   . LEU C 2 157 ? 232.716 214.626 292.584 1.00 65.99  ? 396 LEU G O   1 
ATOM   4933 C CB  . LEU C 2 157 ? 229.876 215.760 292.088 1.00 62.83  ? 396 LEU G CB  1 
ATOM   4934 C CG  . LEU C 2 157 ? 229.202 216.537 293.218 1.00 54.82  ? 396 LEU G CG  1 
ATOM   4935 C CD1 . LEU C 2 157 ? 228.690 217.873 292.716 1.00 59.53  ? 396 LEU G CD1 1 
ATOM   4936 C CD2 . LEU C 2 157 ? 228.073 215.729 293.828 1.00 54.40  ? 396 LEU G CD2 1 
ATOM   4937 N N   . GLU C 2 158 ? 232.819 216.722 293.431 1.00 68.84  ? 397 GLU G N   1 
ATOM   4938 C CA  . GLU C 2 158 ? 234.025 216.490 294.209 1.00 68.44  ? 397 GLU G CA  1 
ATOM   4939 C C   . GLU C 2 158 ? 233.774 216.751 295.686 1.00 73.71  ? 397 GLU G C   1 
ATOM   4940 O O   . GLU C 2 158 ? 232.942 217.584 296.056 1.00 80.08  ? 397 GLU G O   1 
ATOM   4941 C CB  . GLU C 2 158 ? 235.172 217.381 293.717 1.00 68.41  ? 397 GLU G CB  1 
ATOM   4942 C CG  . GLU C 2 158 ? 236.548 216.896 294.113 1.00 70.67  ? 397 GLU G CG  1 
ATOM   4943 C CD  . GLU C 2 158 ? 237.581 218.000 294.106 1.00 83.30  ? 397 GLU G CD  1 
ATOM   4944 O OE1 . GLU C 2 158 ? 237.187 219.184 294.103 1.00 85.87  ? 397 GLU G OE1 1 
ATOM   4945 O OE2 . GLU C 2 158 ? 238.789 217.684 294.105 1.00 85.82  ? 397 GLU G OE2 1 
ATOM   4946 N N   . MET C 2 159 ? 234.502 216.024 296.529 1.00 81.60  ? 398 MET G N   1 
ATOM   4947 C CA  . MET C 2 159 ? 234.564 216.327 297.952 1.00 79.56  ? 398 MET G CA  1 
ATOM   4948 C C   . MET C 2 159 ? 236.016 216.555 298.333 1.00 86.24  ? 398 MET G C   1 
ATOM   4949 O O   . MET C 2 159 ? 236.779 215.595 298.479 1.00 94.83  ? 398 MET G O   1 
ATOM   4950 C CB  . MET C 2 159 ? 233.965 215.206 298.801 1.00 78.50  ? 398 MET G CB  1 
ATOM   4951 C CG  . MET C 2 159 ? 234.035 215.486 300.290 1.00 80.87  ? 398 MET G CG  1 
ATOM   4952 S SD  . MET C 2 159 ? 233.398 214.135 301.293 1.00 88.98  ? 398 MET G SD  1 
ATOM   4953 C CE  . MET C 2 159 ? 234.864 213.139 301.449 1.00 83.19  ? 398 MET G CE  1 
ATOM   4954 N N   . HIS C 2 160 ? 236.396 217.819 298.492 1.00 80.58  ? 399 HIS G N   1 
ATOM   4955 C CA  . HIS C 2 160 ? 237.783 218.171 298.763 1.00 80.76  ? 399 HIS G CA  1 
ATOM   4956 C C   . HIS C 2 160 ? 237.905 218.760 300.157 1.00 79.84  ? 399 HIS G C   1 
ATOM   4957 O O   . HIS C 2 160 ? 237.219 219.732 300.483 1.00 81.03  ? 399 HIS G O   1 
ATOM   4958 C CB  . HIS C 2 160 ? 238.324 219.157 297.727 1.00 83.07  ? 399 HIS G CB  1 
ATOM   4959 C CG  . HIS C 2 160 ? 239.754 218.914 297.359 1.00 88.40  ? 399 HIS G CG  1 
ATOM   4960 N ND1 . HIS C 2 160 ? 240.239 217.661 297.053 1.00 86.13  ? 399 HIS G ND1 1 
ATOM   4961 C CD2 . HIS C 2 160 ? 240.805 219.760 297.253 1.00 89.60  ? 399 HIS G CD2 1 
ATOM   4962 C CE1 . HIS C 2 160 ? 241.527 217.746 296.771 1.00 86.08  ? 399 HIS G CE1 1 
ATOM   4963 N NE2 . HIS C 2 160 ? 241.895 219.009 296.885 1.00 92.36  ? 399 HIS G NE2 1 
ATOM   4964 N N   . LYS C 2 161 ? 238.781 218.164 300.970 1.00 79.18  ? 400 LYS G N   1 
ATOM   4965 C CA  . LYS C 2 161 ? 239.079 218.595 302.340 1.00 81.09  ? 400 LYS G CA  1 
ATOM   4966 C C   . LYS C 2 161 ? 237.815 218.826 303.172 1.00 81.82  ? 400 LYS G C   1 
ATOM   4967 O O   . LYS C 2 161 ? 237.826 219.596 304.138 1.00 80.04  ? 400 LYS G O   1 
ATOM   4968 C CB  . LYS C 2 161 ? 239.989 219.835 302.350 1.00 80.65  ? 400 LYS G CB  1 
ATOM   4969 C CG  . LYS C 2 161 ? 239.329 221.178 302.077 1.00 81.52  ? 400 LYS G CG  1 
ATOM   4970 C CD  . LYS C 2 161 ? 240.045 222.294 302.815 1.00 84.06  ? 400 LYS G CD  1 
ATOM   4971 C CE  . LYS C 2 161 ? 239.996 222.078 304.317 1.00 86.48  ? 400 LYS G CE  1 
ATOM   4972 N NZ  . LYS C 2 161 ? 238.635 221.685 304.774 1.00 84.14  ? 400 LYS G NZ  1 
ATOM   4973 N N   . GLY C 2 162 ? 236.727 218.136 302.838 1.00 77.26  ? 401 GLY G N   1 
ATOM   4974 C CA  . GLY C 2 162 ? 235.498 218.223 303.596 1.00 76.81  ? 401 GLY G CA  1 
ATOM   4975 C C   . GLY C 2 162 ? 234.430 219.113 303.003 1.00 71.58  ? 401 GLY G C   1 
ATOM   4976 O O   . GLY C 2 162 ? 233.348 219.226 303.591 1.00 62.36  ? 401 GLY G O   1 
ATOM   4977 N N   . GLN C 2 163 ? 234.691 219.742 301.863 1.00 73.16  ? 402 GLN G N   1 
ATOM   4978 C CA  . GLN C 2 163 ? 233.734 220.624 301.215 1.00 71.63  ? 402 GLN G CA  1 
ATOM   4979 C C   . GLN C 2 163 ? 233.230 219.973 299.935 1.00 78.38  ? 402 GLN G C   1 
ATOM   4980 O O   . GLN C 2 163 ? 234.006 219.358 299.193 1.00 78.68  ? 402 GLN G O   1 
ATOM   4981 C CB  . GLN C 2 163 ? 234.353 221.997 300.931 1.00 75.05  ? 402 GLN G CB  1 
ATOM   4982 C CG  . GLN C 2 163 ? 235.237 222.076 299.699 1.00 80.98  ? 402 GLN G CG  1 
ATOM   4983 C CD  . GLN C 2 163 ? 236.285 223.164 299.806 1.00 84.95  ? 402 GLN G CD  1 
ATOM   4984 O OE1 . GLN C 2 163 ? 236.156 224.089 300.607 1.00 82.55  ? 402 GLN G OE1 1 
ATOM   4985 N NE2 . GLN C 2 163 ? 237.332 223.059 298.997 1.00 83.99  ? 402 GLN G NE2 1 
ATOM   4986 N N   . TYR C 2 164 ? 231.924 220.084 299.705 1.00 77.62  ? 403 TYR G N   1 
ATOM   4987 C CA  . TYR C 2 164 ? 231.271 219.531 298.527 1.00 72.44  ? 403 TYR G CA  1 
ATOM   4988 C C   . TYR C 2 164 ? 231.275 220.585 297.430 1.00 69.68  ? 403 TYR G C   1 
ATOM   4989 O O   . TYR C 2 164 ? 230.829 221.715 297.652 1.00 69.76  ? 403 TYR G O   1 
ATOM   4990 C CB  . TYR C 2 164 ? 229.842 219.111 298.862 1.00 69.80  ? 403 TYR G CB  1 
ATOM   4991 C CG  . TYR C 2 164 ? 229.731 217.745 299.489 1.00 69.58  ? 403 TYR G CG  1 
ATOM   4992 C CD1 . TYR C 2 164 ? 230.800 216.869 299.478 1.00 64.57  ? 403 TYR G CD1 1 
ATOM   4993 C CD2 . TYR C 2 164 ? 228.568 217.347 300.131 1.00 72.12  ? 403 TYR G CD2 1 
ATOM   4994 C CE1 . TYR C 2 164 ? 230.701 215.628 300.054 1.00 72.71  ? 403 TYR G CE1 1 
ATOM   4995 C CE2 . TYR C 2 164 ? 228.465 216.106 300.716 1.00 72.93  ? 403 TYR G CE2 1 
ATOM   4996 C CZ  . TYR C 2 164 ? 229.539 215.251 300.676 1.00 76.89  ? 403 TYR G CZ  1 
ATOM   4997 O OH  . TYR C 2 164 ? 229.457 214.007 301.255 1.00 83.32  ? 403 TYR G OH  1 
ATOM   4998 N N   . ARG C 2 165 ? 231.769 220.221 296.252 1.00 69.47  ? 404 ARG G N   1 
ATOM   4999 C CA  . ARG C 2 165 ? 231.920 221.178 295.173 1.00 62.04  ? 404 ARG G CA  1 
ATOM   5000 C C   . ARG C 2 165 ? 231.514 220.569 293.838 1.00 69.22  ? 404 ARG G C   1 
ATOM   5001 O O   . ARG C 2 165 ? 231.488 219.348 293.647 1.00 79.92  ? 404 ARG G O   1 
ATOM   5002 C CB  . ARG C 2 165 ? 233.356 221.710 295.083 1.00 64.14  ? 404 ARG G CB  1 
ATOM   5003 C CG  . ARG C 2 165 ? 234.417 220.671 295.356 1.00 70.70  ? 404 ARG G CG  1 
ATOM   5004 C CD  . ARG C 2 165 ? 235.672 221.314 295.907 1.00 66.82  ? 404 ARG G CD  1 
ATOM   5005 N NE  . ARG C 2 165 ? 236.474 221.914 294.850 1.00 62.20  ? 404 ARG G NE  1 
ATOM   5006 C CZ  . ARG C 2 165 ? 237.705 222.374 295.019 1.00 70.57  ? 404 ARG G CZ  1 
ATOM   5007 N NH1 . ARG C 2 165 ? 238.309 222.316 296.194 1.00 68.99  ? 404 ARG G NH1 1 
ATOM   5008 N NH2 . ARG C 2 165 ? 238.348 222.903 293.982 1.00 72.06  ? 404 ARG G NH2 1 
ATOM   5009 N N   . ALA C 2 166 ? 231.244 221.478 292.909 1.00 65.57  ? 405 ALA G N   1 
ATOM   5010 C CA  . ALA C 2 166 ? 230.842 221.235 291.533 1.00 68.88  ? 405 ALA G CA  1 
ATOM   5011 C C   . ALA C 2 166 ? 232.053 220.869 290.690 1.00 71.58  ? 405 ALA G C   1 
ATOM   5012 O O   . ALA C 2 166 ? 233.025 220.302 291.198 1.00 77.06  ? 405 ALA G O   1 
ATOM   5013 C CB  . ALA C 2 166 ? 230.133 222.459 290.957 1.00 69.78  ? 405 ALA G CB  1 
ATOM   5014 N N   . VAL C 2 167 ? 231.995 221.185 289.398 1.00 62.68  ? 406 VAL G N   1 
ATOM   5015 C CA  . VAL C 2 167 ? 232.899 220.715 288.350 1.00 64.53  ? 406 VAL G CA  1 
ATOM   5016 C C   . VAL C 2 167 ? 234.371 220.967 288.669 1.00 66.17  ? 406 VAL G C   1 
ATOM   5017 O O   . VAL C 2 167 ? 235.233 220.810 287.796 1.00 74.41  ? 406 VAL G O   1 
ATOM   5018 C CB  . VAL C 2 167 ? 232.529 221.368 287.007 1.00 66.43  ? 406 VAL G CB  1 
ATOM   5019 C CG1 . VAL C 2 167 ? 231.042 221.258 286.763 1.00 64.73  ? 406 VAL G CG1 1 
ATOM   5020 C CG2 . VAL C 2 167 ? 232.948 222.827 286.997 1.00 69.63  ? 406 VAL G CG2 1 
ATOM   5021 N N   . SER C 2 168 ? 234.656 221.391 289.905 1.00 64.09  ? 407 SER G N   1 
ATOM   5022 C CA  . SER C 2 168 ? 235.986 221.641 290.464 1.00 68.28  ? 407 SER G CA  1 
ATOM   5023 C C   . SER C 2 168 ? 236.531 223.018 290.124 1.00 69.55  ? 407 SER G C   1 
ATOM   5024 O O   . SER C 2 168 ? 237.744 223.237 290.188 1.00 72.43  ? 407 SER G O   1 
ATOM   5025 C CB  . SER C 2 168 ? 237.009 220.575 290.054 1.00 68.53  ? 407 SER G CB  1 
ATOM   5026 O OG  . SER C 2 168 ? 236.462 219.273 290.168 1.00 64.31  ? 407 SER G OG  1 
ATOM   5027 N N   . SER C 2 169 ? 235.663 223.958 289.759 1.00 79.96  ? 408 SER G N   1 
ATOM   5028 C CA  . SER C 2 169 ? 235.987 225.370 289.886 1.00 85.51  ? 408 SER G CA  1 
ATOM   5029 C C   . SER C 2 169 ? 235.681 225.769 291.323 1.00 81.10  ? 408 SER G C   1 
ATOM   5030 O O   . SER C 2 169 ? 234.512 225.713 291.731 1.00 75.35  ? 408 SER G O   1 
ATOM   5031 C CB  . SER C 2 169 ? 235.176 226.207 288.909 1.00 83.45  ? 408 SER G CB  1 
ATOM   5032 O OG  . SER C 2 169 ? 235.348 227.590 289.160 1.00 84.81  ? 408 SER G OG  1 
ATOM   5033 N N   . PRO C 2 170 ? 236.671 226.170 292.120 1.00 75.07  ? 409 PRO G N   1 
ATOM   5034 C CA  . PRO C 2 170 ? 236.430 226.362 293.560 1.00 73.80  ? 409 PRO G CA  1 
ATOM   5035 C C   . PRO C 2 170 ? 235.465 227.494 293.887 1.00 78.92  ? 409 PRO G C   1 
ATOM   5036 O O   . PRO C 2 170 ? 235.253 227.803 295.063 1.00 84.30  ? 409 PRO G O   1 
ATOM   5037 C CB  . PRO C 2 170 ? 237.827 226.650 294.131 1.00 69.95  ? 409 PRO G CB  1 
ATOM   5038 C CG  . PRO C 2 170 ? 238.760 226.720 292.990 1.00 68.86  ? 409 PRO G CG  1 
ATOM   5039 C CD  . PRO C 2 170 ? 238.097 226.223 291.758 1.00 75.92  ? 409 PRO G CD  1 
ATOM   5040 N N   . ASP C 2 171 ? 234.876 228.118 292.869 1.00 82.85  ? 410 ASP G N   1 
ATOM   5041 C CA  . ASP C 2 171 ? 233.987 229.254 293.070 1.00 88.22  ? 410 ASP G CA  1 
ATOM   5042 C C   . ASP C 2 171 ? 232.514 228.867 293.152 1.00 85.62  ? 410 ASP G C   1 
ATOM   5043 O O   . ASP C 2 171 ? 231.657 229.757 293.158 1.00 86.39  ? 410 ASP G O   1 
ATOM   5044 C CB  . ASP C 2 171 ? 234.187 230.276 291.943 1.00 89.82  ? 410 ASP G CB  1 
ATOM   5045 C CG  . ASP C 2 171 ? 233.682 231.658 292.308 1.00 93.62  ? 410 ASP G CG  1 
ATOM   5046 O OD1 . ASP C 2 171 ? 233.944 232.107 293.444 1.00 92.06  ? 410 ASP G OD1 1 
ATOM   5047 O OD2 . ASP C 2 171 ? 233.023 232.295 291.460 1.00 93.79  ? 410 ASP G OD2 1 
ATOM   5048 N N   . ARG C 2 172 ? 232.191 227.576 293.220 1.00 63.59  ? 411 ARG G N   1 
ATOM   5049 C CA  . ARG C 2 172 ? 230.793 227.158 293.227 1.00 63.52  ? 411 ARG G CA  1 
ATOM   5050 C C   . ARG C 2 172 ? 230.495 226.123 294.306 1.00 67.19  ? 411 ARG G C   1 
ATOM   5051 O O   . ARG C 2 172 ? 229.892 225.084 294.021 1.00 70.74  ? 411 ARG G O   1 
ATOM   5052 C CB  . ARG C 2 172 ? 230.397 226.609 291.855 1.00 61.04  ? 411 ARG G CB  1 
ATOM   5053 C CG  . ARG C 2 172 ? 231.490 225.818 291.173 1.00 58.03  ? 411 ARG G CG  1 
ATOM   5054 C CD  . ARG C 2 172 ? 231.209 225.637 289.694 1.00 61.48  ? 411 ARG G CD  1 
ATOM   5055 N NE  . ARG C 2 172 ? 231.620 226.791 288.907 1.00 65.86  ? 411 ARG G NE  1 
ATOM   5056 C CZ  . ARG C 2 172 ? 231.619 226.827 287.582 1.00 64.82  ? 411 ARG G CZ  1 
ATOM   5057 N NH1 . ARG C 2 172 ? 231.237 225.785 286.863 1.00 61.00  ? 411 ARG G NH1 1 
ATOM   5058 N NH2 . ARG C 2 172 ? 232.011 227.936 286.963 1.00 68.29  ? 411 ARG G NH2 1 
ATOM   5059 N N   . ILE C 2 173 ? 230.914 226.389 295.544 1.00 65.37  ? 412 ILE G N   1 
ATOM   5060 C CA  . ILE C 2 173 ? 230.643 225.468 296.642 1.00 68.50  ? 412 ILE G CA  1 
ATOM   5061 C C   . ILE C 2 173 ? 229.150 225.458 296.944 1.00 67.70  ? 412 ILE G C   1 
ATOM   5062 O O   . ILE C 2 173 ? 228.536 226.512 297.155 1.00 69.03  ? 412 ILE G O   1 
ATOM   5063 C CB  . ILE C 2 173 ? 231.458 225.859 297.883 1.00 66.69  ? 412 ILE G CB  1 
ATOM   5064 C CG1 . ILE C 2 173 ? 232.907 226.161 297.498 1.00 62.35  ? 412 ILE G CG1 1 
ATOM   5065 C CG2 . ILE C 2 173 ? 231.399 224.756 298.926 1.00 65.28  ? 412 ILE G CG2 1 
ATOM   5066 C CD1 . ILE C 2 173 ? 233.701 224.942 297.107 1.00 59.34  ? 412 ILE G CD1 1 
ATOM   5067 N N   . LEU C 2 174 ? 228.557 224.261 296.971 1.00 73.85  ? 413 LEU G N   1 
ATOM   5068 C CA  . LEU C 2 174 ? 227.120 224.111 297.144 1.00 71.02  ? 413 LEU G CA  1 
ATOM   5069 C C   . LEU C 2 174 ? 226.733 224.182 298.614 1.00 70.15  ? 413 LEU G C   1 
ATOM   5070 O O   . LEU C 2 174 ? 227.541 223.890 299.500 1.00 70.50  ? 413 LEU G O   1 
ATOM   5071 C CB  . LEU C 2 174 ? 226.647 222.781 296.557 1.00 73.50  ? 413 LEU G CB  1 
ATOM   5072 C CG  . LEU C 2 174 ? 227.214 222.261 295.235 1.00 76.94  ? 413 LEU G CG  1 
ATOM   5073 C CD1 . LEU C 2 174 ? 228.425 221.384 295.479 1.00 72.15  ? 413 LEU G CD1 1 
ATOM   5074 C CD2 . LEU C 2 174 ? 226.151 221.499 294.461 1.00 74.79  ? 413 LEU G CD2 1 
ATOM   5075 N N   . PRO C 2 175 ? 225.488 224.575 298.907 1.00 70.47  ? 414 PRO G N   1 
ATOM   5076 C CA  . PRO C 2 175 ? 224.982 224.555 300.296 1.00 70.90  ? 414 PRO G CA  1 
ATOM   5077 C C   . PRO C 2 175 ? 224.402 223.196 300.677 1.00 69.42  ? 414 PRO G C   1 
ATOM   5078 O O   . PRO C 2 175 ? 223.185 222.978 300.702 1.00 65.28  ? 414 PRO G O   1 
ATOM   5079 C CB  . PRO C 2 175 ? 223.926 225.661 300.271 1.00 70.78  ? 414 PRO G CB  1 
ATOM   5080 C CG  . PRO C 2 175 ? 223.388 225.620 298.881 1.00 67.31  ? 414 PRO G CG  1 
ATOM   5081 C CD  . PRO C 2 175 ? 224.519 225.186 297.979 1.00 67.68  ? 414 PRO G CD  1 
ATOM   5082 N N   . LEU C 2 176 ? 225.288 222.252 300.986 1.00 73.48  ? 415 LEU G N   1 
ATOM   5083 C CA  . LEU C 2 176 ? 224.887 220.891 301.314 1.00 72.16  ? 415 LEU G CA  1 
ATOM   5084 C C   . LEU C 2 176 ? 224.956 220.668 302.819 1.00 72.89  ? 415 LEU G C   1 
ATOM   5085 O O   . LEU C 2 176 ? 225.996 220.904 303.443 1.00 66.94  ? 415 LEU G O   1 
ATOM   5086 C CB  . LEU C 2 176 ? 225.765 219.882 300.575 1.00 66.60  ? 415 LEU G CB  1 
ATOM   5087 C CG  . LEU C 2 176 ? 225.121 219.414 299.271 1.00 67.14  ? 415 LEU G CG  1 
ATOM   5088 C CD1 . LEU C 2 176 ? 226.131 218.815 298.316 1.00 71.21  ? 415 LEU G CD1 1 
ATOM   5089 C CD2 . LEU C 2 176 ? 224.037 218.410 299.593 1.00 68.14  ? 415 LEU G CD2 1 
ATOM   5090 N N   . LYS C 2 177 ? 223.841 220.205 303.392 1.00 77.67  ? 416 LYS G N   1 
ATOM   5091 C CA  . LYS C 2 177 ? 223.721 220.112 304.844 1.00 75.51  ? 416 LYS G CA  1 
ATOM   5092 C C   . LYS C 2 177 ? 224.730 219.132 305.427 1.00 69.53  ? 416 LYS G C   1 
ATOM   5093 O O   . LYS C 2 177 ? 225.487 219.474 306.343 1.00 68.99  ? 416 LYS G O   1 
ATOM   5094 C CB  . LYS C 2 177 ? 222.300 219.694 305.228 1.00 69.88  ? 416 LYS G CB  1 
ATOM   5095 C CG  . LYS C 2 177 ? 221.208 220.206 304.306 1.00 67.08  ? 416 LYS G CG  1 
ATOM   5096 C CD  . LYS C 2 177 ? 221.135 221.719 304.314 1.00 65.05  ? 416 LYS G CD  1 
ATOM   5097 C CE  . LYS C 2 177 ? 220.722 222.240 302.956 1.00 63.90  ? 416 LYS G CE  1 
ATOM   5098 N NZ  . LYS C 2 177 ? 221.719 221.869 301.923 1.00 63.81  ? 416 LYS G NZ  1 
ATOM   5099 N N   . GLU C 2 178 ? 224.763 217.912 304.904 1.00 65.84  ? 417 GLU G N   1 
ATOM   5100 C CA  . GLU C 2 178 ? 225.505 216.825 305.522 1.00 74.88  ? 417 GLU G CA  1 
ATOM   5101 C C   . GLU C 2 178 ? 226.262 216.038 304.461 1.00 71.23  ? 417 GLU G C   1 
ATOM   5102 O O   . GLU C 2 178 ? 226.118 216.269 303.258 1.00 72.61  ? 417 GLU G O   1 
ATOM   5103 C CB  . GLU C 2 178 ? 224.568 215.897 306.309 1.00 68.41  ? 417 GLU G CB  1 
ATOM   5104 C CG  . GLU C 2 178 ? 223.883 214.833 305.465 1.00 68.15  ? 417 GLU G CG  1 
ATOM   5105 C CD  . GLU C 2 178 ? 223.067 215.413 304.329 1.00 69.65  ? 417 GLU G CD  1 
ATOM   5106 O OE1 . GLU C 2 178 ? 222.532 216.531 304.485 1.00 60.12  ? 417 GLU G OE1 1 
ATOM   5107 O OE2 . GLU C 2 178 ? 222.965 214.752 303.276 1.00 71.33  ? 417 GLU G OE2 1 
ATOM   5108 N N   . SER C 2 179 ? 227.077 215.097 304.931 1.00 63.78  ? 418 SER G N   1 
ATOM   5109 C CA  . SER C 2 179 ? 227.857 214.251 304.046 1.00 64.23  ? 418 SER G CA  1 
ATOM   5110 C C   . SER C 2 179 ? 226.937 213.418 303.154 1.00 68.34  ? 418 SER G C   1 
ATOM   5111 O O   . SER C 2 179 ? 225.730 213.311 303.377 1.00 66.49  ? 418 SER G O   1 
ATOM   5112 C CB  . SER C 2 179 ? 228.776 213.338 304.857 1.00 63.98  ? 418 SER G CB  1 
ATOM   5113 O OG  . SER C 2 179 ? 229.562 214.086 305.767 1.00 64.86  ? 418 SER G OG  1 
ATOM   5114 N N   . LEU C 2 180 ? 227.531 212.819 302.128 1.00 68.09  ? 419 LEU G N   1 
ATOM   5115 C CA  . LEU C 2 180 ? 226.792 212.028 301.153 1.00 58.71  ? 419 LEU G CA  1 
ATOM   5116 C C   . LEU C 2 180 ? 226.969 210.548 301.463 1.00 68.21  ? 419 LEU G C   1 
ATOM   5117 O O   . LEU C 2 180 ? 228.099 210.057 301.550 1.00 69.17  ? 419 LEU G O   1 
ATOM   5118 C CB  . LEU C 2 180 ? 227.260 212.335 299.732 1.00 53.38  ? 419 LEU G CB  1 
ATOM   5119 C CG  . LEU C 2 180 ? 226.578 213.528 299.068 1.00 59.59  ? 419 LEU G CG  1 
ATOM   5120 C CD1 . LEU C 2 180 ? 226.910 213.578 297.589 1.00 67.91  ? 419 LEU G CD1 1 
ATOM   5121 C CD2 . LEU C 2 180 ? 225.079 213.464 299.285 1.00 58.85  ? 419 LEU G CD2 1 
ATOM   5122 N N   . CYS C 2 181 ? 225.849 209.846 301.633 1.00 77.30  ? 420 CYS G N   1 
ATOM   5123 C CA  . CYS C 2 181 ? 225.890 208.397 301.783 1.00 71.10  ? 420 CYS G CA  1 
ATOM   5124 C C   . CYS C 2 181 ? 225.969 207.712 300.424 1.00 67.88  ? 420 CYS G C   1 
ATOM   5125 O O   . CYS C 2 181 ? 226.940 207.008 300.128 1.00 62.69  ? 420 CYS G O   1 
ATOM   5126 C CB  . CYS C 2 181 ? 224.657 207.916 302.550 1.00 68.70  ? 420 CYS G CB  1 
ATOM   5127 S SG  . CYS C 2 181 ? 224.808 207.966 304.349 1.00 83.17  ? 420 CYS G SG  1 
ATOM   5128 N N   . ARG C 2 182 ? 224.956 207.920 299.586 1.00 57.40  ? 421 ARG G N   1 
ATOM   5129 C CA  . ARG C 2 182 ? 224.894 207.330 298.255 1.00 53.62  ? 421 ARG G CA  1 
ATOM   5130 C C   . ARG C 2 182 ? 224.597 208.440 297.261 1.00 52.93  ? 421 ARG G C   1 
ATOM   5131 O O   . ARG C 2 182 ? 223.628 209.184 297.435 1.00 53.91  ? 421 ARG G O   1 
ATOM   5132 C CB  . ARG C 2 182 ? 223.823 206.237 298.188 1.00 60.30  ? 421 ARG G CB  1 
ATOM   5133 C CG  . ARG C 2 182 ? 224.091 205.149 297.164 1.00 61.94  ? 421 ARG G CG  1 
ATOM   5134 C CD  . ARG C 2 182 ? 223.328 203.883 297.507 1.00 52.80  ? 421 ARG G CD  1 
ATOM   5135 N NE  . ARG C 2 182 ? 221.888 204.097 297.538 1.00 53.12  ? 421 ARG G NE  1 
ATOM   5136 C CZ  . ARG C 2 182 ? 221.081 203.606 298.468 1.00 52.26  ? 421 ARG G CZ  1 
ATOM   5137 N NH1 . ARG C 2 182 ? 221.545 202.881 299.471 1.00 54.93  ? 421 ARG G NH1 1 
ATOM   5138 N NH2 . ARG C 2 182 ? 219.777 203.850 298.389 1.00 52.90  ? 421 ARG G NH2 1 
ATOM   5139 N N   . VAL C 2 183 ? 225.428 208.552 296.228 1.00 55.73  ? 422 VAL G N   1 
ATOM   5140 C CA  . VAL C 2 183 ? 225.327 209.623 295.243 1.00 52.25  ? 422 VAL G CA  1 
ATOM   5141 C C   . VAL C 2 183 ? 225.064 209.003 293.880 1.00 49.65  ? 422 VAL G C   1 
ATOM   5142 O O   . VAL C 2 183 ? 225.773 208.082 293.461 1.00 59.07  ? 422 VAL G O   1 
ATOM   5143 C CB  . VAL C 2 183 ? 226.597 210.494 295.221 1.00 54.55  ? 422 VAL G CB  1 
ATOM   5144 C CG1 . VAL C 2 183 ? 227.844 209.628 295.196 1.00 54.59  ? 422 VAL G CG1 1 
ATOM   5145 C CG2 . VAL C 2 183 ? 226.577 211.434 294.030 1.00 47.80  ? 422 VAL G CG2 1 
ATOM   5146 N N   . GLY C 2 184 ? 224.040 209.496 293.195 1.00 44.74  ? 423 GLY G N   1 
ATOM   5147 C CA  . GLY C 2 184 ? 223.668 208.982 291.890 1.00 46.58  ? 423 GLY G CA  1 
ATOM   5148 C C   . GLY C 2 184 ? 224.099 209.932 290.787 1.00 54.34  ? 423 GLY G C   1 
ATOM   5149 O O   . GLY C 2 184 ? 223.876 211.137 290.871 1.00 61.96  ? 423 GLY G O   1 
ATOM   5150 N N   . VAL C 2 185 ? 224.723 209.377 289.756 1.00 47.33  ? 424 VAL G N   1 
ATOM   5151 C CA  . VAL C 2 185 ? 225.108 210.135 288.574 1.00 47.93  ? 424 VAL G CA  1 
ATOM   5152 C C   . VAL C 2 185 ? 224.122 209.797 287.467 1.00 42.74  ? 424 VAL G C   1 
ATOM   5153 O O   . VAL C 2 185 ? 224.011 208.634 287.059 1.00 45.97  ? 424 VAL G O   1 
ATOM   5154 C CB  . VAL C 2 185 ? 226.550 209.823 288.152 1.00 50.02  ? 424 VAL G CB  1 
ATOM   5155 C CG1 . VAL C 2 185 ? 226.938 210.658 286.947 1.00 46.73  ? 424 VAL G CG1 1 
ATOM   5156 C CG2 . VAL C 2 185 ? 227.498 210.075 289.307 1.00 51.71  ? 424 VAL G CG2 1 
ATOM   5157 N N   . PHE C 2 186 ? 223.401 210.808 286.992 1.00 34.29  ? 425 PHE G N   1 
ATOM   5158 C CA  . PHE C 2 186 ? 222.403 210.670 285.944 1.00 32.43  ? 425 PHE G CA  1 
ATOM   5159 C C   . PHE C 2 186 ? 222.881 211.390 284.690 1.00 42.45  ? 425 PHE G C   1 
ATOM   5160 O O   . PHE C 2 186 ? 223.483 212.463 284.763 1.00 42.59  ? 425 PHE G O   1 
ATOM   5161 C CB  . PHE C 2 186 ? 221.057 211.234 286.408 1.00 36.83  ? 425 PHE G CB  1 
ATOM   5162 C CG  . PHE C 2 186 ? 220.080 211.491 285.295 1.00 43.06  ? 425 PHE G CG  1 
ATOM   5163 C CD1 . PHE C 2 186 ? 219.233 210.493 284.857 1.00 42.64  ? 425 PHE G CD1 1 
ATOM   5164 C CD2 . PHE C 2 186 ? 219.989 212.742 284.710 1.00 46.41  ? 425 PHE G CD2 1 
ATOM   5165 C CE1 . PHE C 2 186 ? 218.331 210.730 283.842 1.00 46.55  ? 425 PHE G CE1 1 
ATOM   5166 C CE2 . PHE C 2 186 ? 219.090 212.982 283.695 1.00 42.13  ? 425 PHE G CE2 1 
ATOM   5167 C CZ  . PHE C 2 186 ? 218.259 211.976 283.262 1.00 44.63  ? 425 PHE G CZ  1 
ATOM   5168 N N   . LEU C 2 187 ? 222.597 210.791 283.535 1.00 54.46  ? 426 LEU G N   1 
ATOM   5169 C CA  . LEU C 2 187 ? 223.167 211.232 282.272 1.00 50.19  ? 426 LEU G CA  1 
ATOM   5170 C C   . LEU C 2 187 ? 222.116 211.168 281.175 1.00 44.10  ? 426 LEU G C   1 
ATOM   5171 O O   . LEU C 2 187 ? 221.465 210.135 280.988 1.00 44.10  ? 426 LEU G O   1 
ATOM   5172 C CB  . LEU C 2 187 ? 224.380 210.372 281.907 1.00 49.04  ? 426 LEU G CB  1 
ATOM   5173 C CG  . LEU C 2 187 ? 225.131 210.648 280.610 1.00 43.24  ? 426 LEU G CG  1 
ATOM   5174 C CD1 . LEU C 2 187 ? 226.588 210.363 280.852 1.00 52.69  ? 426 LEU G CD1 1 
ATOM   5175 C CD2 . LEU C 2 187 ? 224.613 209.792 279.471 1.00 42.56  ? 426 LEU G CD2 1 
ATOM   5176 N N   . ASP C 2 188 ? 221.969 212.276 280.453 1.00 44.17  ? 427 ASP G N   1 
ATOM   5177 C CA  . ASP C 2 188 ? 221.053 212.392 279.323 1.00 50.54  ? 427 ASP G CA  1 
ATOM   5178 C C   . ASP C 2 188 ? 221.859 212.934 278.151 1.00 48.74  ? 427 ASP G C   1 
ATOM   5179 O O   . ASP C 2 188 ? 222.286 214.095 278.171 1.00 50.89  ? 427 ASP G O   1 
ATOM   5180 C CB  . ASP C 2 188 ? 219.874 213.306 279.656 1.00 55.91  ? 427 ASP G CB  1 
ATOM   5181 C CG  . ASP C 2 188 ? 218.726 213.162 278.680 1.00 61.36  ? 427 ASP G CG  1 
ATOM   5182 O OD1 . ASP C 2 188 ? 218.877 212.427 277.684 1.00 60.42  ? 427 ASP G OD1 1 
ATOM   5183 O OD2 . ASP C 2 188 ? 217.669 213.786 278.911 1.00 59.81  ? 427 ASP G OD2 1 
ATOM   5184 N N   . TYR C 2 189 ? 222.073 212.086 277.141 1.00 49.39  ? 428 TYR G N   1 
ATOM   5185 C CA  . TYR C 2 189 ? 222.993 212.416 276.058 1.00 53.17  ? 428 TYR G CA  1 
ATOM   5186 C C   . TYR C 2 189 ? 222.407 213.436 275.091 1.00 56.80  ? 428 TYR G C   1 
ATOM   5187 O O   . TYR C 2 189 ? 223.109 214.365 274.676 1.00 64.14  ? 428 TYR G O   1 
ATOM   5188 C CB  . TYR C 2 189 ? 223.390 211.145 275.311 1.00 45.28  ? 428 TYR G CB  1 
ATOM   5189 C CG  . TYR C 2 189 ? 224.638 211.284 274.475 1.00 49.06  ? 428 TYR G CG  1 
ATOM   5190 C CD1 . TYR C 2 189 ? 225.892 211.054 275.021 1.00 51.12  ? 428 TYR G CD1 1 
ATOM   5191 C CD2 . TYR C 2 189 ? 224.563 211.641 273.138 1.00 51.78  ? 428 TYR G CD2 1 
ATOM   5192 C CE1 . TYR C 2 189 ? 227.034 211.176 274.260 1.00 54.50  ? 428 TYR G CE1 1 
ATOM   5193 C CE2 . TYR C 2 189 ? 225.698 211.768 272.369 1.00 52.13  ? 428 TYR G CE2 1 
ATOM   5194 C CZ  . TYR C 2 189 ? 226.930 211.534 272.934 1.00 56.43  ? 428 TYR G CZ  1 
ATOM   5195 O OH  . TYR C 2 189 ? 228.063 211.661 272.166 1.00 58.41  ? 428 TYR G OH  1 
ATOM   5196 N N   . GLU C 2 190 ? 221.138 213.290 274.722 1.00 51.62  ? 429 GLU G N   1 
ATOM   5197 C CA  . GLU C 2 190 ? 220.505 214.208 273.785 1.00 48.69  ? 429 GLU G CA  1 
ATOM   5198 C C   . GLU C 2 190 ? 220.144 215.543 274.421 1.00 55.04  ? 429 GLU G C   1 
ATOM   5199 O O   . GLU C 2 190 ? 219.456 216.349 273.788 1.00 64.65  ? 429 GLU G O   1 
ATOM   5200 C CB  . GLU C 2 190 ? 219.251 213.572 273.173 1.00 56.25  ? 429 GLU G CB  1 
ATOM   5201 C CG  . GLU C 2 190 ? 219.424 212.152 272.621 1.00 63.06  ? 429 GLU G CG  1 
ATOM   5202 C CD  . GLU C 2 190 ? 219.488 211.072 273.693 1.00 68.96  ? 429 GLU G CD  1 
ATOM   5203 O OE1 . GLU C 2 190 ? 219.241 209.893 273.359 1.00 63.11  ? 429 GLU G OE1 1 
ATOM   5204 O OE2 . GLU C 2 190 ? 219.779 211.395 274.865 1.00 69.83  ? 429 GLU G OE2 1 
ATOM   5205 N N   . ALA C 2 191 ? 220.588 215.791 275.650 1.00 53.24  ? 430 ALA G N   1 
ATOM   5206 C CA  . ALA C 2 191 ? 220.319 217.051 276.321 1.00 47.78  ? 430 ALA G CA  1 
ATOM   5207 C C   . ALA C 2 191 ? 221.526 217.604 277.060 1.00 50.51  ? 430 ALA G C   1 
ATOM   5208 O O   . ALA C 2 191 ? 221.385 218.615 277.754 1.00 56.78  ? 430 ALA G O   1 
ATOM   5209 C CB  . ALA C 2 191 ? 219.157 216.893 277.309 1.00 40.58  ? 430 ALA G CB  1 
ATOM   5210 N N   . GLY C 2 192 ? 222.695 216.980 276.942 1.00 49.56  ? 431 GLY G N   1 
ATOM   5211 C CA  . GLY C 2 192 ? 223.857 217.423 277.684 1.00 49.64  ? 431 GLY G CA  1 
ATOM   5212 C C   . GLY C 2 192 ? 223.671 217.435 279.181 1.00 50.63  ? 431 GLY G C   1 
ATOM   5213 O O   . GLY C 2 192 ? 224.318 218.226 279.870 1.00 54.56  ? 431 GLY G O   1 
ATOM   5214 N N   . ASP C 2 193 ? 222.804 216.576 279.713 1.00 52.80  ? 432 ASP G N   1 
ATOM   5215 C CA  . ASP C 2 193 ? 222.448 216.625 281.127 1.00 54.51  ? 432 ASP G CA  1 
ATOM   5216 C C   . ASP C 2 193 ? 223.356 215.689 281.912 1.00 52.73  ? 432 ASP G C   1 
ATOM   5217 O O   . ASP C 2 193 ? 223.327 214.473 281.711 1.00 61.72  ? 432 ASP G O   1 
ATOM   5218 C CB  . ASP C 2 193 ? 220.982 216.256 281.334 1.00 60.56  ? 432 ASP G CB  1 
ATOM   5219 C CG  . ASP C 2 193 ? 220.091 217.467 281.480 1.00 58.20  ? 432 ASP G CG  1 
ATOM   5220 O OD1 . ASP C 2 193 ? 220.627 218.581 281.645 1.00 66.51  ? 432 ASP G OD1 1 
ATOM   5221 O OD2 . ASP C 2 193 ? 218.854 217.306 281.440 1.00 55.28  ? 432 ASP G OD2 1 
ATOM   5222 N N   . VAL C 2 194 ? 224.158 216.254 282.803 1.00 39.99  ? 433 VAL G N   1 
ATOM   5223 C CA  . VAL C 2 194 ? 224.919 215.488 283.779 1.00 46.01  ? 433 VAL G CA  1 
ATOM   5224 C C   . VAL C 2 194 ? 224.457 215.969 285.147 1.00 51.55  ? 433 VAL G C   1 
ATOM   5225 O O   . VAL C 2 194 ? 224.812 217.068 285.586 1.00 62.12  ? 433 VAL G O   1 
ATOM   5226 C CB  . VAL C 2 194 ? 226.431 215.657 283.599 1.00 43.12  ? 433 VAL G CB  1 
ATOM   5227 C CG1 . VAL C 2 194 ? 227.171 215.035 284.769 1.00 44.66  ? 433 VAL G CG1 1 
ATOM   5228 C CG2 . VAL C 2 194 ? 226.879 215.031 282.292 1.00 49.40  ? 433 VAL G CG2 1 
ATOM   5229 N N   . SER C 2 195 ? 223.654 215.156 285.821 1.00 45.76  ? 434 SER G N   1 
ATOM   5230 C CA  . SER C 2 195 ? 223.073 215.517 287.103 1.00 43.87  ? 434 SER G CA  1 
ATOM   5231 C C   . SER C 2 195 ? 223.664 214.655 288.206 1.00 40.15  ? 434 SER G C   1 
ATOM   5232 O O   . SER C 2 195 ? 223.929 213.465 288.009 1.00 49.22  ? 434 SER G O   1 
ATOM   5233 C CB  . SER C 2 195 ? 221.550 215.362 287.082 1.00 45.90  ? 434 SER G CB  1 
ATOM   5234 O OG  . SER C 2 195 ? 220.951 216.255 286.160 1.00 42.17  ? 434 SER G OG  1 
ATOM   5235 N N   . PHE C 2 196 ? 223.880 215.265 289.362 1.00 41.51  ? 435 PHE G N   1 
ATOM   5236 C CA  . PHE C 2 196 ? 224.278 214.557 290.564 1.00 47.95  ? 435 PHE G CA  1 
ATOM   5237 C C   . PHE C 2 196 ? 223.141 214.638 291.571 1.00 50.20  ? 435 PHE G C   1 
ATOM   5238 O O   . PHE C 2 196 ? 222.635 215.728 291.862 1.00 63.49  ? 435 PHE G O   1 
ATOM   5239 C CB  . PHE C 2 196 ? 225.564 215.145 291.144 1.00 59.28  ? 435 PHE G CB  1 
ATOM   5240 C CG  . PHE C 2 196 ? 226.663 215.301 290.132 1.00 51.59  ? 435 PHE G CG  1 
ATOM   5241 C CD1 . PHE C 2 196 ? 227.350 214.197 289.663 1.00 46.96  ? 435 PHE G CD1 1 
ATOM   5242 C CD2 . PHE C 2 196 ? 227.006 216.550 289.648 1.00 48.74  ? 435 PHE G CD2 1 
ATOM   5243 C CE1 . PHE C 2 196 ? 228.359 214.336 288.732 1.00 47.27  ? 435 PHE G CE1 1 
ATOM   5244 C CE2 . PHE C 2 196 ? 228.014 216.694 288.717 1.00 48.63  ? 435 PHE G CE2 1 
ATOM   5245 C CZ  . PHE C 2 196 ? 228.690 215.585 288.259 1.00 47.79  ? 435 PHE G CZ  1 
ATOM   5246 N N   . TYR C 2 197 ? 222.743 213.476 292.084 1.00 40.55  ? 436 TYR G N   1 
ATOM   5247 C CA  . TYR C 2 197 ? 221.558 213.310 292.908 1.00 46.10  ? 436 TYR G CA  1 
ATOM   5248 C C   . TYR C 2 197 ? 221.938 212.735 294.265 1.00 47.08  ? 436 TYR G C   1 
ATOM   5249 O O   . TYR C 2 197 ? 222.831 211.888 294.370 1.00 50.96  ? 436 TYR G O   1 
ATOM   5250 C CB  . TYR C 2 197 ? 220.552 212.367 292.237 1.00 45.28  ? 436 TYR G CB  1 
ATOM   5251 C CG  . TYR C 2 197 ? 219.542 213.029 291.331 1.00 45.37  ? 436 TYR G CG  1 
ATOM   5252 C CD1 . TYR C 2 197 ? 219.919 213.556 290.106 1.00 46.00  ? 436 TYR G CD1 1 
ATOM   5253 C CD2 . TYR C 2 197 ? 218.205 213.097 291.689 1.00 47.41  ? 436 TYR G CD2 1 
ATOM   5254 C CE1 . TYR C 2 197 ? 218.994 214.150 289.272 1.00 50.38  ? 436 TYR G CE1 1 
ATOM   5255 C CE2 . TYR C 2 197 ? 217.275 213.686 290.862 1.00 46.83  ? 436 TYR G CE2 1 
ATOM   5256 C CZ  . TYR C 2 197 ? 217.674 214.212 289.655 1.00 50.38  ? 436 TYR G CZ  1 
ATOM   5257 O OH  . TYR C 2 197 ? 216.747 214.802 288.829 1.00 52.65  ? 436 TYR G OH  1 
ATOM   5258 N N   . ASN C 2 198 ? 221.234 213.189 295.298 1.00 49.66  ? 437 ASN G N   1 
ATOM   5259 C CA  . ASN C 2 198 ? 221.373 212.644 296.647 1.00 48.80  ? 437 ASN G CA  1 
ATOM   5260 C C   . ASN C 2 198 ? 220.472 211.421 296.744 1.00 62.96  ? 437 ASN G C   1 
ATOM   5261 O O   . ASN C 2 198 ? 219.247 211.543 296.808 1.00 62.12  ? 437 ASN G O   1 
ATOM   5262 C CB  . ASN C 2 198 ? 221.008 213.692 297.692 1.00 47.93  ? 437 ASN G CB  1 
ATOM   5263 C CG  . ASN C 2 198 ? 220.991 213.135 299.094 1.00 57.43  ? 437 ASN G CG  1 
ATOM   5264 O OD1 . ASN C 2 198 ? 222.007 212.661 299.598 1.00 59.37  ? 437 ASN G OD1 1 
ATOM   5265 N ND2 . ASN C 2 198 ? 219.833 213.192 299.738 1.00 60.63  ? 437 ASN G ND2 1 
ATOM   5266 N N   . MET C 2 199 ? 221.080 210.234 296.763 1.00 65.32  ? 438 MET G N   1 
ATOM   5267 C CA  . MET C 2 199 ? 220.312 208.997 296.693 1.00 51.88  ? 438 MET G CA  1 
ATOM   5268 C C   . MET C 2 199 ? 219.773 208.544 298.040 1.00 50.26  ? 438 MET G C   1 
ATOM   5269 O O   . MET C 2 199 ? 219.032 207.557 298.089 1.00 51.48  ? 438 MET G O   1 
ATOM   5270 C CB  . MET C 2 199 ? 221.160 207.886 296.079 1.00 42.25  ? 438 MET G CB  1 
ATOM   5271 C CG  . MET C 2 199 ? 220.935 207.729 294.596 1.00 52.21  ? 438 MET G CG  1 
ATOM   5272 S SD  . MET C 2 199 ? 219.207 207.955 294.153 1.00 58.88  ? 438 MET G SD  1 
ATOM   5273 C CE  . MET C 2 199 ? 219.323 207.972 292.372 1.00 47.48  ? 438 MET G CE  1 
ATOM   5274 N N   . ARG C 2 200 ? 220.125 209.227 299.129 1.00 57.29  ? 439 ARG G N   1 
ATOM   5275 C CA  . ARG C 2 200 ? 219.452 208.970 300.396 1.00 57.38  ? 439 ARG G CA  1 
ATOM   5276 C C   . ARG C 2 200 ? 217.965 209.284 300.301 1.00 62.24  ? 439 ARG G C   1 
ATOM   5277 O O   . ARG C 2 200 ? 217.150 208.646 300.976 1.00 66.28  ? 439 ARG G O   1 
ATOM   5278 C CB  . ARG C 2 200 ? 220.102 209.791 301.508 1.00 62.85  ? 439 ARG G CB  1 
ATOM   5279 C CG  . ARG C 2 200 ? 219.538 209.531 302.891 1.00 67.96  ? 439 ARG G CG  1 
ATOM   5280 C CD  . ARG C 2 200 ? 220.223 210.408 303.934 1.00 70.59  ? 439 ARG G CD  1 
ATOM   5281 N NE  . ARG C 2 200 ? 219.881 211.827 303.839 1.00 70.82  ? 439 ARG G NE  1 
ATOM   5282 C CZ  . ARG C 2 200 ? 218.653 212.331 303.784 1.00 66.90  ? 439 ARG G CZ  1 
ATOM   5283 N NH1 . ARG C 2 200 ? 217.578 211.569 303.901 1.00 64.05  ? 439 ARG G NH1 1 
ATOM   5284 N NH2 . ARG C 2 200 ? 218.500 213.643 303.632 1.00 62.43  ? 439 ARG G NH2 1 
ATOM   5285 N N   . ASP C 2 201 ? 217.592 210.252 299.461 1.00 60.78  ? 440 ASP G N   1 
ATOM   5286 C CA  . ASP C 2 201 ? 216.200 210.644 299.290 1.00 61.45  ? 440 ASP G CA  1 
ATOM   5287 C C   . ASP C 2 201 ? 215.831 210.863 297.827 1.00 59.81  ? 440 ASP G C   1 
ATOM   5288 O O   . ASP C 2 201 ? 214.713 211.313 297.545 1.00 61.82  ? 440 ASP G O   1 
ATOM   5289 C CB  . ASP C 2 201 ? 215.902 211.912 300.100 1.00 61.47  ? 440 ASP G CB  1 
ATOM   5290 C CG  . ASP C 2 201 ? 214.417 212.159 300.278 1.00 66.80  ? 440 ASP G CG  1 
ATOM   5291 O OD1 . ASP C 2 201 ? 213.631 211.203 300.119 1.00 67.64  ? 440 ASP G OD1 1 
ATOM   5292 O OD2 . ASP C 2 201 ? 214.037 213.311 300.571 1.00 66.70  ? 440 ASP G OD2 1 
ATOM   5293 N N   . ARG C 2 202 ? 216.727 210.544 296.890 1.00 47.57  ? 441 ARG G N   1 
ATOM   5294 C CA  . ARG C 2 202 ? 216.505 210.801 295.466 1.00 45.17  ? 441 ARG G CA  1 
ATOM   5295 C C   . ARG C 2 202 ? 216.191 212.277 295.230 1.00 50.53  ? 441 ARG G C   1 
ATOM   5296 O O   . ARG C 2 202 ? 215.201 212.633 294.587 1.00 56.61  ? 441 ARG G O   1 
ATOM   5297 C CB  . ARG C 2 202 ? 215.398 209.906 294.902 1.00 54.45  ? 441 ARG G CB  1 
ATOM   5298 C CG  . ARG C 2 202 ? 215.679 208.416 295.008 1.00 56.35  ? 441 ARG G CG  1 
ATOM   5299 C CD  . ARG C 2 202 ? 215.684 207.753 293.642 1.00 44.32  ? 441 ARG G CD  1 
ATOM   5300 N NE  . ARG C 2 202 ? 214.342 207.615 293.092 1.00 42.52  ? 441 ARG G NE  1 
ATOM   5301 C CZ  . ARG C 2 202 ? 214.055 206.953 291.981 1.00 47.27  ? 441 ARG G CZ  1 
ATOM   5302 N NH1 . ARG C 2 202 ? 214.995 206.352 291.273 1.00 53.62  ? 441 ARG G NH1 1 
ATOM   5303 N NH2 . ARG C 2 202 ? 212.792 206.891 291.571 1.00 50.08  ? 441 ARG G NH2 1 
ATOM   5304 N N   . SER C 2 203 ? 217.046 213.141 295.768 1.00 52.61  ? 442 SER G N   1 
ATOM   5305 C CA  . SER C 2 203 ? 216.849 214.580 295.724 1.00 52.59  ? 442 SER G CA  1 
ATOM   5306 C C   . SER C 2 203 ? 217.909 215.234 294.847 1.00 50.33  ? 442 SER G C   1 
ATOM   5307 O O   . SER C 2 203 ? 219.068 214.810 294.823 1.00 59.65  ? 442 SER G O   1 
ATOM   5308 C CB  . SER C 2 203 ? 216.896 215.182 297.130 1.00 53.32  ? 442 SER G CB  1 
ATOM   5309 O OG  . SER C 2 203 ? 216.402 216.507 297.132 1.00 58.04  ? 442 SER G OG  1 
ATOM   5310 N N   . HIS C 2 204 ? 217.494 216.268 294.120 1.00 42.11  ? 443 HIS G N   1 
ATOM   5311 C CA  . HIS C 2 204 ? 218.407 216.988 293.244 1.00 44.50  ? 443 HIS G CA  1 
ATOM   5312 C C   . HIS C 2 204 ? 219.519 217.641 294.052 1.00 45.99  ? 443 HIS G C   1 
ATOM   5313 O O   . HIS C 2 204 ? 219.272 218.267 295.086 1.00 56.14  ? 443 HIS G O   1 
ATOM   5314 C CB  . HIS C 2 204 ? 217.646 218.047 292.447 1.00 48.12  ? 443 HIS G CB  1 
ATOM   5315 C CG  . HIS C 2 204 ? 218.367 218.521 291.223 1.00 49.32  ? 443 HIS G CG  1 
ATOM   5316 N ND1 . HIS C 2 204 ? 219.647 219.029 291.263 1.00 53.17  ? 443 HIS G ND1 1 
ATOM   5317 C CD2 . HIS C 2 204 ? 217.983 218.572 289.927 1.00 52.89  ? 443 HIS G CD2 1 
ATOM   5318 C CE1 . HIS C 2 204 ? 220.023 219.367 290.043 1.00 50.38  ? 443 HIS G CE1 1 
ATOM   5319 N NE2 . HIS C 2 204 ? 219.031 219.100 289.213 1.00 50.93  ? 443 HIS G NE2 1 
ATOM   5320 N N   . ILE C 2 205 ? 220.753 217.496 293.574 1.00 46.12  ? 444 ILE G N   1 
ATOM   5321 C CA  . ILE C 2 205 ? 221.922 218.090 294.210 1.00 50.37  ? 444 ILE G CA  1 
ATOM   5322 C C   . ILE C 2 205 ? 222.613 219.084 293.287 1.00 47.99  ? 444 ILE G C   1 
ATOM   5323 O O   . ILE C 2 205 ? 222.901 220.218 293.681 1.00 55.31  ? 444 ILE G O   1 
ATOM   5324 C CB  . ILE C 2 205 ? 222.915 217.009 294.689 1.00 46.77  ? 444 ILE G CB  1 
ATOM   5325 C CG1 . ILE C 2 205 ? 222.416 216.380 295.985 1.00 52.44  ? 444 ILE G CG1 1 
ATOM   5326 C CG2 . ILE C 2 205 ? 224.300 217.598 294.887 1.00 45.11  ? 444 ILE G CG2 1 
ATOM   5327 C CD1 . ILE C 2 205 ? 221.871 217.377 296.974 1.00 57.91  ? 444 ILE G CD1 1 
ATOM   5328 N N   . TYR C 2 206 ? 222.882 218.680 292.048 1.00 44.79  ? 445 TYR G N   1 
ATOM   5329 C CA  . TYR C 2 206 ? 223.563 219.584 291.132 1.00 42.84  ? 445 TYR G CA  1 
ATOM   5330 C C   . TYR C 2 206 ? 223.257 219.193 289.695 1.00 46.11  ? 445 TYR G C   1 
ATOM   5331 O O   . TYR C 2 206 ? 223.027 218.019 289.401 1.00 53.03  ? 445 TYR G O   1 
ATOM   5332 C CB  . TYR C 2 206 ? 225.075 219.571 291.377 1.00 50.45  ? 445 TYR G CB  1 
ATOM   5333 C CG  . TYR C 2 206 ? 225.851 220.563 290.545 1.00 52.15  ? 445 TYR G CG  1 
ATOM   5334 C CD1 . TYR C 2 206 ? 225.524 221.910 290.551 1.00 52.54  ? 445 TYR G CD1 1 
ATOM   5335 C CD2 . TYR C 2 206 ? 226.918 220.153 289.764 1.00 48.12  ? 445 TYR G CD2 1 
ATOM   5336 C CE1 . TYR C 2 206 ? 226.234 222.818 289.794 1.00 49.12  ? 445 TYR G CE1 1 
ATOM   5337 C CE2 . TYR C 2 206 ? 227.632 221.053 289.005 1.00 48.00  ? 445 TYR G CE2 1 
ATOM   5338 C CZ  . TYR C 2 206 ? 227.286 222.384 289.024 1.00 49.14  ? 445 TYR G CZ  1 
ATOM   5339 O OH  . TYR C 2 206 ? 227.998 223.283 288.269 1.00 56.17  ? 445 TYR G OH  1 
ATOM   5340 N N   . THR C 2 207 ? 223.256 220.185 288.808 1.00 53.33  ? 446 THR G N   1 
ATOM   5341 C CA  . THR C 2 207 ? 223.167 219.969 287.370 1.00 56.28  ? 446 THR G CA  1 
ATOM   5342 C C   . THR C 2 207 ? 224.338 220.679 286.709 1.00 55.62  ? 446 THR G C   1 
ATOM   5343 O O   . THR C 2 207 ? 224.526 221.885 286.904 1.00 67.39  ? 446 THR G O   1 
ATOM   5344 C CB  . THR C 2 207 ? 221.844 220.486 286.804 1.00 55.97  ? 446 THR G CB  1 
ATOM   5345 O OG1 . THR C 2 207 ? 220.802 219.544 287.082 1.00 63.36  ? 446 THR G OG1 1 
ATOM   5346 C CG2 . THR C 2 207 ? 221.950 220.684 285.300 1.00 44.41  ? 446 THR G CG2 1 
ATOM   5347 N N   . CYS C 2 208 ? 225.124 219.937 285.938 1.00 46.70  ? 447 CYS G N   1 
ATOM   5348 C CA  . CYS C 2 208 ? 226.242 220.536 285.235 1.00 51.54  ? 447 CYS G CA  1 
ATOM   5349 C C   . CYS C 2 208 ? 225.733 221.425 284.102 1.00 59.32  ? 447 CYS G C   1 
ATOM   5350 O O   . CYS C 2 208 ? 224.673 221.163 283.527 1.00 61.08  ? 447 CYS G O   1 
ATOM   5351 C CB  . CYS C 2 208 ? 227.159 219.457 284.672 1.00 60.05  ? 447 CYS G CB  1 
ATOM   5352 S SG  . CYS C 2 208 ? 228.537 219.015 285.743 1.00 80.12  ? 447 CYS G SG  1 
ATOM   5353 N N   . PRO C 2 209 ? 226.461 222.492 283.773 1.00 62.37  ? 448 PRO G N   1 
ATOM   5354 C CA  . PRO C 2 209 ? 226.086 223.305 282.612 1.00 52.91  ? 448 PRO G CA  1 
ATOM   5355 C C   . PRO C 2 209 ? 226.071 222.462 281.347 1.00 57.02  ? 448 PRO G C   1 
ATOM   5356 O O   . PRO C 2 209 ? 226.916 221.587 281.154 1.00 63.83  ? 448 PRO G O   1 
ATOM   5357 C CB  . PRO C 2 209 ? 227.178 224.378 282.563 1.00 46.99  ? 448 PRO G CB  1 
ATOM   5358 C CG  . PRO C 2 209 ? 227.691 224.455 283.956 1.00 49.93  ? 448 PRO G CG  1 
ATOM   5359 C CD  . PRO C 2 209 ? 227.601 223.066 284.506 1.00 59.07  ? 448 PRO G CD  1 
ATOM   5360 N N   . ARG C 2 210 ? 225.092 222.728 280.487 1.00 46.38  ? 449 ARG G N   1 
ATOM   5361 C CA  . ARG C 2 210 ? 224.899 221.897 279.309 1.00 44.50  ? 449 ARG G CA  1 
ATOM   5362 C C   . ARG C 2 210 ? 226.097 222.001 278.374 1.00 47.23  ? 449 ARG G C   1 
ATOM   5363 O O   . ARG C 2 210 ? 226.627 223.089 278.132 1.00 51.08  ? 449 ARG G O   1 
ATOM   5364 C CB  . ARG C 2 210 ? 223.619 222.302 278.579 1.00 50.33  ? 449 ARG G CB  1 
ATOM   5365 C CG  . ARG C 2 210 ? 222.342 221.924 279.304 1.00 39.94  ? 449 ARG G CG  1 
ATOM   5366 C CD  . ARG C 2 210 ? 221.169 221.852 278.345 1.00 41.78  ? 449 ARG G CD  1 
ATOM   5367 N NE  . ARG C 2 210 ? 219.917 222.251 278.976 1.00 46.78  ? 449 ARG G NE  1 
ATOM   5368 C CZ  . ARG C 2 210 ? 219.075 221.415 279.565 1.00 43.71  ? 449 ARG G CZ  1 
ATOM   5369 N NH1 . ARG C 2 210 ? 219.324 220.119 279.633 1.00 48.66  ? 449 ARG G NH1 1 
ATOM   5370 N NH2 . ARG C 2 210 ? 217.954 221.891 280.098 1.00 44.19  ? 449 ARG G NH2 1 
ATOM   5371 N N   . SER C 2 211 ? 226.530 220.855 277.855 1.00 42.03  ? 450 SER G N   1 
ATOM   5372 C CA  . SER C 2 211 ? 227.689 220.803 276.968 1.00 49.60  ? 450 SER G CA  1 
ATOM   5373 C C   . SER C 2 211 ? 227.559 219.566 276.094 1.00 50.46  ? 450 SER G C   1 
ATOM   5374 O O   . SER C 2 211 ? 227.660 218.442 276.595 1.00 58.41  ? 450 SER G O   1 
ATOM   5375 C CB  . SER C 2 211 ? 228.990 220.772 277.764 1.00 50.75  ? 450 SER G CB  1 
ATOM   5376 O OG  . SER C 2 211 ? 230.046 220.252 276.978 1.00 48.76  ? 450 SER G OG  1 
ATOM   5377 N N   . ALA C 2 212 ? 227.334 219.771 274.798 1.00 46.03  ? 451 ALA G N   1 
ATOM   5378 C CA  . ALA C 2 212 ? 227.180 218.652 273.879 1.00 47.70  ? 451 ALA G CA  1 
ATOM   5379 C C   . ALA C 2 212 ? 228.454 217.819 273.841 1.00 45.47  ? 451 ALA G C   1 
ATOM   5380 O O   . ALA C 2 212 ? 229.559 218.355 273.723 1.00 52.68  ? 451 ALA G O   1 
ATOM   5381 C CB  . ALA C 2 212 ? 226.832 219.158 272.481 1.00 47.95  ? 451 ALA G CB  1 
ATOM   5382 N N   . PHE C 2 213 ? 228.294 216.501 273.945 1.00 44.07  ? 452 PHE G N   1 
ATOM   5383 C CA  . PHE C 2 213 ? 229.445 215.607 273.991 1.00 48.79  ? 452 PHE G CA  1 
ATOM   5384 C C   . PHE C 2 213 ? 229.917 215.248 272.587 1.00 50.42  ? 452 PHE G C   1 
ATOM   5385 O O   . PHE C 2 213 ? 231.099 215.395 272.261 1.00 53.58  ? 452 PHE G O   1 
ATOM   5386 C CB  . PHE C 2 213 ? 229.098 214.340 274.781 1.00 60.47  ? 452 PHE G CB  1 
ATOM   5387 C CG  . PHE C 2 213 ? 228.172 214.578 275.943 1.00 60.94  ? 452 PHE G CG  1 
ATOM   5388 C CD1 . PHE C 2 213 ? 228.669 214.964 277.175 1.00 53.64  ? 452 PHE G CD1 1 
ATOM   5389 C CD2 . PHE C 2 213 ? 226.806 214.407 275.804 1.00 54.93  ? 452 PHE G CD2 1 
ATOM   5390 C CE1 . PHE C 2 213 ? 227.822 215.180 278.242 1.00 42.35  ? 452 PHE G CE1 1 
ATOM   5391 C CE2 . PHE C 2 213 ? 225.955 214.624 276.867 1.00 45.84  ? 452 PHE G CE2 1 
ATOM   5392 C CZ  . PHE C 2 213 ? 226.464 215.010 278.087 1.00 38.92  ? 452 PHE G CZ  1 
ATOM   5393 N N   . SER C 2 214 ? 229.000 214.760 271.748 1.00 62.70  ? 453 SER G N   1 
ATOM   5394 C CA  . SER C 2 214 ? 229.248 214.347 270.367 1.00 66.72  ? 453 SER G CA  1 
ATOM   5395 C C   . SER C 2 214 ? 230.213 213.167 270.291 1.00 61.36  ? 453 SER G C   1 
ATOM   5396 O O   . SER C 2 214 ? 230.545 212.702 269.197 1.00 68.72  ? 453 SER G O   1 
ATOM   5397 C CB  . SER C 2 214 ? 229.769 215.510 269.508 1.00 64.65  ? 453 SER G CB  1 
ATOM   5398 O OG  . SER C 2 214 ? 230.806 216.243 270.136 1.00 68.69  ? 453 SER G OG  1 
ATOM   5399 N N   . VAL C 2 215 ? 230.661 212.676 271.440 1.00 46.82  ? 454 VAL G N   1 
ATOM   5400 C CA  . VAL C 2 215 ? 231.484 211.472 271.513 1.00 49.48  ? 454 VAL G CA  1 
ATOM   5401 C C   . VAL C 2 215 ? 230.924 210.613 272.640 1.00 60.39  ? 454 VAL G C   1 
ATOM   5402 O O   . VAL C 2 215 ? 230.314 211.152 273.574 1.00 64.61  ? 454 VAL G O   1 
ATOM   5403 C CB  . VAL C 2 215 ? 232.966 211.810 271.738 1.00 47.98  ? 454 VAL G CB  1 
ATOM   5404 C CG1 . VAL C 2 215 ? 233.605 212.280 270.447 1.00 52.41  ? 454 VAL G CG1 1 
ATOM   5405 C CG2 . VAL C 2 215 ? 233.108 212.863 272.810 1.00 50.28  ? 454 VAL G CG2 1 
ATOM   5406 N N   . PRO C 2 216 ? 231.081 209.291 272.590 1.00 56.62  ? 455 PRO G N   1 
ATOM   5407 C CA  . PRO C 2 216 ? 230.544 208.449 273.665 1.00 48.09  ? 455 PRO G CA  1 
ATOM   5408 C C   . PRO C 2 216 ? 231.134 208.822 275.017 1.00 54.44  ? 455 PRO G C   1 
ATOM   5409 O O   . PRO C 2 216 ? 232.314 209.157 275.132 1.00 57.65  ? 455 PRO G O   1 
ATOM   5410 C CB  . PRO C 2 216 ? 230.951 207.035 273.242 1.00 47.85  ? 455 PRO G CB  1 
ATOM   5411 C CG  . PRO C 2 216 ? 231.094 207.117 271.764 1.00 46.70  ? 455 PRO G CG  1 
ATOM   5412 C CD  . PRO C 2 216 ? 231.618 208.490 271.478 1.00 53.10  ? 455 PRO G CD  1 
ATOM   5413 N N   . VAL C 2 217 ? 230.293 208.761 276.045 1.00 51.23  ? 456 VAL G N   1 
ATOM   5414 C CA  . VAL C 2 217 ? 230.652 209.162 277.400 1.00 52.15  ? 456 VAL G CA  1 
ATOM   5415 C C   . VAL C 2 217 ? 230.713 207.926 278.286 1.00 51.15  ? 456 VAL G C   1 
ATOM   5416 O O   . VAL C 2 217 ? 229.978 206.956 278.068 1.00 48.00  ? 456 VAL G O   1 
ATOM   5417 C CB  . VAL C 2 217 ? 229.650 210.194 277.948 1.00 46.44  ? 456 VAL G CB  1 
ATOM   5418 C CG1 . VAL C 2 217 ? 229.752 211.483 277.166 1.00 45.25  ? 456 VAL G CG1 1 
ATOM   5419 C CG2 . VAL C 2 217 ? 228.245 209.649 277.844 1.00 52.33  ? 456 VAL G CG2 1 
ATOM   5420 N N   . ARG C 2 218 ? 231.596 207.957 279.281 1.00 51.91  ? 457 ARG G N   1 
ATOM   5421 C CA  . ARG C 2 218 ? 231.825 206.823 280.159 1.00 51.76  ? 457 ARG G CA  1 
ATOM   5422 C C   . ARG C 2 218 ? 231.980 207.282 281.601 1.00 51.86  ? 457 ARG G C   1 
ATOM   5423 O O   . ARG C 2 218 ? 232.438 208.401 281.859 1.00 55.17  ? 457 ARG G O   1 
ATOM   5424 C CB  . ARG C 2 218 ? 233.079 206.047 279.733 1.00 54.06  ? 457 ARG G CB  1 
ATOM   5425 C CG  . ARG C 2 218 ? 232.966 205.377 278.378 1.00 54.00  ? 457 ARG G CG  1 
ATOM   5426 C CD  . ARG C 2 218 ? 234.335 205.091 277.793 1.00 57.55  ? 457 ARG G CD  1 
ATOM   5427 N NE  . ARG C 2 218 ? 235.053 204.068 278.542 1.00 48.34  ? 457 ARG G NE  1 
ATOM   5428 C CZ  . ARG C 2 218 ? 236.367 203.899 278.505 1.00 53.99  ? 457 ARG G CZ  1 
ATOM   5429 N NH1 . ARG C 2 218 ? 237.142 204.676 277.768 1.00 58.43  ? 457 ARG G NH1 1 
ATOM   5430 N NH2 . ARG C 2 218 ? 236.917 202.927 279.225 1.00 55.80  ? 457 ARG G NH2 1 
ATOM   5431 N N   . PRO C 2 219 ? 231.616 206.434 282.561 1.00 56.23  ? 458 PRO G N   1 
ATOM   5432 C CA  . PRO C 2 219 ? 231.761 206.808 283.972 1.00 59.03  ? 458 PRO G CA  1 
ATOM   5433 C C   . PRO C 2 219 ? 233.221 206.955 284.372 1.00 61.29  ? 458 PRO G C   1 
ATOM   5434 O O   . PRO C 2 219 ? 234.116 206.334 283.794 1.00 55.28  ? 458 PRO G O   1 
ATOM   5435 C CB  . PRO C 2 219 ? 231.095 205.646 284.719 1.00 63.77  ? 458 PRO G CB  1 
ATOM   5436 C CG  . PRO C 2 219 ? 230.226 204.977 283.701 1.00 57.47  ? 458 PRO G CG  1 
ATOM   5437 C CD  . PRO C 2 219 ? 230.936 205.139 282.401 1.00 54.68  ? 458 PRO G CD  1 
ATOM   5438 N N   . PHE C 2 220 ? 233.451 207.786 285.389 1.00 67.35  ? 459 PHE G N   1 
ATOM   5439 C CA  . PHE C 2 220 ? 234.789 208.180 285.806 1.00 67.58  ? 459 PHE G CA  1 
ATOM   5440 C C   . PHE C 2 220 ? 234.797 208.396 287.313 1.00 60.42  ? 459 PHE G C   1 
ATOM   5441 O O   . PHE C 2 220 ? 233.932 209.101 287.847 1.00 68.41  ? 459 PHE G O   1 
ATOM   5442 C CB  . PHE C 2 220 ? 235.214 209.455 285.062 1.00 67.82  ? 459 PHE G CB  1 
ATOM   5443 C CG  . PHE C 2 220 ? 236.305 210.232 285.737 1.00 59.09  ? 459 PHE G CG  1 
ATOM   5444 C CD1 . PHE C 2 220 ? 237.631 209.935 285.495 1.00 58.92  ? 459 PHE G CD1 1 
ATOM   5445 C CD2 . PHE C 2 220 ? 236.005 211.280 286.590 1.00 59.92  ? 459 PHE G CD2 1 
ATOM   5446 C CE1 . PHE C 2 220 ? 238.631 210.656 286.102 1.00 65.01  ? 459 PHE G CE1 1 
ATOM   5447 C CE2 . PHE C 2 220 ? 237.006 211.998 287.204 1.00 62.58  ? 459 PHE G CE2 1 
ATOM   5448 C CZ  . PHE C 2 220 ? 238.319 211.685 286.960 1.00 63.08  ? 459 PHE G CZ  1 
ATOM   5449 N N   . PHE C 2 221 ? 235.769 207.789 287.995 1.00 60.76  ? 460 PHE G N   1 
ATOM   5450 C CA  . PHE C 2 221 ? 235.875 207.901 289.443 1.00 71.59  ? 460 PHE G CA  1 
ATOM   5451 C C   . PHE C 2 221 ? 237.322 208.170 289.832 1.00 75.23  ? 460 PHE G C   1 
ATOM   5452 O O   . PHE C 2 221 ? 238.241 207.609 289.234 1.00 71.97  ? 460 PHE G O   1 
ATOM   5453 C CB  . PHE C 2 221 ? 235.386 206.625 290.143 1.00 68.49  ? 460 PHE G CB  1 
ATOM   5454 C CG  . PHE C 2 221 ? 234.063 206.123 289.643 1.00 63.41  ? 460 PHE G CG  1 
ATOM   5455 C CD1 . PHE C 2 221 ? 232.880 206.687 290.084 1.00 66.26  ? 460 PHE G CD1 1 
ATOM   5456 C CD2 . PHE C 2 221 ? 234.003 205.080 288.737 1.00 63.71  ? 460 PHE G CD2 1 
ATOM   5457 C CE1 . PHE C 2 221 ? 231.664 206.225 289.627 1.00 67.88  ? 460 PHE G CE1 1 
ATOM   5458 C CE2 . PHE C 2 221 ? 232.790 204.614 288.278 1.00 66.86  ? 460 PHE G CE2 1 
ATOM   5459 C CZ  . PHE C 2 221 ? 231.619 205.188 288.723 1.00 67.06  ? 460 PHE G CZ  1 
ATOM   5460 N N   . ARG C 2 222 ? 237.523 209.023 290.836 1.00 81.06  ? 461 ARG G N   1 
ATOM   5461 C CA  . ARG C 2 222 ? 238.854 209.287 291.363 1.00 76.29  ? 461 ARG G CA  1 
ATOM   5462 C C   . ARG C 2 222 ? 238.803 209.301 292.882 1.00 75.69  ? 461 ARG G C   1 
ATOM   5463 O O   . ARG C 2 222 ? 237.826 209.771 293.475 1.00 69.74  ? 461 ARG G O   1 
ATOM   5464 C CB  . ARG C 2 222 ? 239.424 210.616 290.848 1.00 84.82  ? 461 ARG G CB  1 
ATOM   5465 C CG  . ARG C 2 222 ? 240.914 210.794 291.117 1.00 83.16  ? 461 ARG G CG  1 
ATOM   5466 C CD  . ARG C 2 222 ? 241.388 212.206 290.824 1.00 75.96  ? 461 ARG G CD  1 
ATOM   5467 N NE  . ARG C 2 222 ? 241.348 213.050 292.011 1.00 72.47  ? 461 ARG G NE  1 
ATOM   5468 C CZ  . ARG C 2 222 ? 240.772 214.242 292.060 1.00 79.56  ? 461 ARG G CZ  1 
ATOM   5469 N NH1 . ARG C 2 222 ? 240.166 214.761 291.005 1.00 82.30  ? 461 ARG G NH1 1 
ATOM   5470 N NH2 . ARG C 2 222 ? 240.799 214.929 293.198 1.00 80.35  ? 461 ARG G NH2 1 
ATOM   5471 N N   . LEU C 2 223 ? 239.873 208.807 293.500 1.00 78.99  ? 462 LEU G N   1 
ATOM   5472 C CA  . LEU C 2 223 ? 239.953 208.642 294.943 1.00 75.65  ? 462 LEU G CA  1 
ATOM   5473 C C   . LEU C 2 223 ? 241.235 209.270 295.465 1.00 75.50  ? 462 LEU G C   1 
ATOM   5474 O O   . LEU C 2 223 ? 242.251 209.302 294.766 1.00 81.32  ? 462 LEU G O   1 
ATOM   5475 C CB  . LEU C 2 223 ? 239.911 207.163 295.327 1.00 73.52  ? 462 LEU G CB  1 
ATOM   5476 C CG  . LEU C 2 223 ? 238.524 206.528 295.367 1.00 78.71  ? 462 LEU G CG  1 
ATOM   5477 C CD1 . LEU C 2 223 ? 238.580 205.192 296.082 1.00 81.91  ? 462 LEU G CD1 1 
ATOM   5478 C CD2 . LEU C 2 223 ? 237.539 207.466 296.040 1.00 83.14  ? 462 LEU G CD2 1 
ATOM   5479 N N   . GLY C 2 224 ? 241.182 209.764 296.698 1.00 84.05  ? 463 GLY G N   1 
ATOM   5480 C CA  . GLY C 2 224 ? 242.348 210.357 297.321 1.00 87.30  ? 463 GLY G CA  1 
ATOM   5481 C C   . GLY C 2 224 ? 242.706 209.715 298.644 1.00 92.78  ? 463 GLY G C   1 
ATOM   5482 O O   . GLY C 2 224 ? 243.841 209.832 299.113 1.00 92.42  ? 463 GLY G O   1 
ATOM   5483 N N   . CYS C 2 225 ? 241.744 209.028 299.252 1.00 98.15  ? 464 CYS G N   1 
ATOM   5484 C CA  . CYS C 2 225 ? 241.949 208.380 300.536 1.00 92.49  ? 464 CYS G CA  1 
ATOM   5485 C C   . CYS C 2 225 ? 242.881 207.180 300.396 1.00 93.52  ? 464 CYS G C   1 
ATOM   5486 O O   . CYS C 2 225 ? 243.369 206.851 299.312 1.00 98.34  ? 464 CYS G O   1 
ATOM   5487 C CB  . CYS C 2 225 ? 240.613 207.949 301.133 1.00 91.95  ? 464 CYS G CB  1 
ATOM   5488 S SG  . CYS C 2 225 ? 240.512 208.081 302.933 1.00 104.90 ? 464 CYS G SG  1 
ATOM   5489 N N   . GLU C 2 226 ? 243.133 206.520 301.522 1.00 100.48 ? 465 GLU G N   1 
ATOM   5490 C CA  . GLU C 2 226 ? 243.890 205.277 301.565 1.00 102.61 ? 465 GLU G CA  1 
ATOM   5491 C C   . GLU C 2 226 ? 243.034 204.226 302.255 1.00 105.96 ? 465 GLU G C   1 
ATOM   5492 O O   . GLU C 2 226 ? 242.783 204.323 303.462 1.00 107.10 ? 465 GLU G O   1 
ATOM   5493 C CB  . GLU C 2 226 ? 245.219 205.464 302.296 1.00 103.09 ? 465 GLU G CB  1 
ATOM   5494 C CG  . GLU C 2 226 ? 246.216 206.328 301.546 1.00 104.30 ? 465 GLU G CG  1 
ATOM   5495 C CD  . GLU C 2 226 ? 246.369 205.919 300.095 1.00 107.10 ? 465 GLU G CD  1 
ATOM   5496 O OE1 . GLU C 2 226 ? 246.566 204.715 299.831 1.00 105.30 ? 465 GLU G OE1 1 
ATOM   5497 O OE2 . GLU C 2 226 ? 246.292 206.804 299.217 1.00 109.74 ? 465 GLU G OE2 1 
ATOM   5498 N N   . ASP C 2 227 ? 242.583 203.233 301.487 1.00 111.42 ? 466 ASP G N   1 
ATOM   5499 C CA  . ASP C 2 227 ? 241.732 202.154 301.992 1.00 111.73 ? 466 ASP G CA  1 
ATOM   5500 C C   . ASP C 2 227 ? 240.430 202.699 302.581 1.00 109.72 ? 466 ASP G C   1 
ATOM   5501 O O   . ASP C 2 227 ? 240.101 202.468 303.745 1.00 108.57 ? 466 ASP G O   1 
ATOM   5502 C CB  . ASP C 2 227 ? 242.479 201.294 303.014 1.00 111.77 ? 466 ASP G CB  1 
ATOM   5503 C CG  . ASP C 2 227 ? 243.925 201.062 302.631 1.00 113.91 ? 466 ASP G CG  1 
ATOM   5504 O OD1 . ASP C 2 227 ? 244.217 201.022 301.418 1.00 115.60 ? 466 ASP G OD1 1 
ATOM   5505 O OD2 . ASP C 2 227 ? 244.769 200.924 303.541 1.00 114.36 ? 466 ASP G OD2 1 
ATOM   5506 N N   . SER C 2 228 ? 239.688 203.433 301.760 1.00 96.88  ? 467 SER G N   1 
ATOM   5507 C CA  . SER C 2 228 ? 238.359 203.919 302.130 1.00 93.76  ? 467 SER G CA  1 
ATOM   5508 C C   . SER C 2 228 ? 237.341 203.368 301.146 1.00 96.94  ? 467 SER G C   1 
ATOM   5509 O O   . SER C 2 228 ? 237.274 203.845 299.998 1.00 100.28 ? 467 SER G O   1 
ATOM   5510 C CB  . SER C 2 228 ? 238.316 205.445 302.145 1.00 98.35  ? 467 SER G CB  1 
ATOM   5511 O OG  . SER C 2 228 ? 238.927 205.957 303.316 1.00 100.68 ? 467 SER G OG  1 
ATOM   5512 N N   . PRO C 2 229 ? 236.545 202.372 301.533 1.00 98.23  ? 468 PRO G N   1 
ATOM   5513 C CA  . PRO C 2 229 ? 235.667 201.695 300.566 1.00 95.09  ? 468 PRO G CA  1 
ATOM   5514 C C   . PRO C 2 229 ? 234.671 202.612 299.875 1.00 90.98  ? 468 PRO G C   1 
ATOM   5515 O O   . PRO C 2 229 ? 233.883 203.300 300.531 1.00 93.09  ? 468 PRO G O   1 
ATOM   5516 C CB  . PRO C 2 229 ? 234.937 200.648 301.422 1.00 99.53  ? 468 PRO G CB  1 
ATOM   5517 C CG  . PRO C 2 229 ? 235.275 200.971 302.854 1.00 102.32 ? 468 PRO G CG  1 
ATOM   5518 C CD  . PRO C 2 229 ? 236.581 201.678 302.828 1.00 99.70  ? 468 PRO G CD  1 
ATOM   5519 N N   . ILE C 2 230 ? 234.701 202.621 298.545 1.00 73.31  ? 469 ILE G N   1 
ATOM   5520 C CA  . ILE C 2 230 ? 233.659 203.231 297.731 1.00 74.63  ? 469 ILE G CA  1 
ATOM   5521 C C   . ILE C 2 230 ? 233.018 202.121 296.913 1.00 74.12  ? 469 ILE G C   1 
ATOM   5522 O O   . ILE C 2 230 ? 233.713 201.229 296.411 1.00 79.19  ? 469 ILE G O   1 
ATOM   5523 C CB  . ILE C 2 230 ? 234.199 204.365 296.836 1.00 79.26  ? 469 ILE G CB  1 
ATOM   5524 C CG1 . ILE C 2 230 ? 234.772 203.839 295.519 1.00 74.40  ? 469 ILE G CG1 1 
ATOM   5525 C CG2 . ILE C 2 230 ? 235.248 205.166 297.580 1.00 81.99  ? 469 ILE G CG2 1 
ATOM   5526 C CD1 . ILE C 2 230 ? 234.852 204.888 294.436 1.00 69.54  ? 469 ILE G CD1 1 
ATOM   5527 N N   . PHE C 2 231 ? 231.693 202.138 296.832 1.00 64.85  ? 470 PHE G N   1 
ATOM   5528 C CA  . PHE C 2 231 ? 230.956 201.023 296.261 1.00 73.92  ? 470 PHE G CA  1 
ATOM   5529 C C   . PHE C 2 231 ? 230.063 201.506 295.132 1.00 68.31  ? 470 PHE G C   1 
ATOM   5530 O O   . PHE C 2 231 ? 229.217 202.383 295.329 1.00 69.04  ? 470 PHE G O   1 
ATOM   5531 C CB  . PHE C 2 231 ? 230.108 200.316 297.328 1.00 80.20  ? 470 PHE G CB  1 
ATOM   5532 C CG  . PHE C 2 231 ? 230.919 199.648 298.402 1.00 76.83  ? 470 PHE G CG  1 
ATOM   5533 C CD1 . PHE C 2 231 ? 231.948 198.786 298.074 1.00 68.29  ? 470 PHE G CD1 1 
ATOM   5534 C CD2 . PHE C 2 231 ? 230.654 199.886 299.738 1.00 73.73  ? 470 PHE G CD2 1 
ATOM   5535 C CE1 . PHE C 2 231 ? 232.697 198.174 299.051 1.00 65.92  ? 470 PHE G CE1 1 
ATOM   5536 C CE2 . PHE C 2 231 ? 231.401 199.275 300.723 1.00 73.49  ? 470 PHE G CE2 1 
ATOM   5537 C CZ  . PHE C 2 231 ? 232.424 198.417 300.378 1.00 72.96  ? 470 PHE G CZ  1 
ATOM   5538 N N   . ILE C 2 232 ? 230.254 200.926 293.954 1.00 57.03  ? 471 ILE G N   1 
ATOM   5539 C CA  . ILE C 2 232 ? 229.349 201.117 292.830 1.00 56.29  ? 471 ILE G CA  1 
ATOM   5540 C C   . ILE C 2 232 ? 228.192 200.152 293.023 1.00 56.14  ? 471 ILE G C   1 
ATOM   5541 O O   . ILE C 2 232 ? 228.380 198.931 292.981 1.00 67.32  ? 471 ILE G O   1 
ATOM   5542 C CB  . ILE C 2 232 ? 230.052 200.875 291.487 1.00 56.99  ? 471 ILE G CB  1 
ATOM   5543 C CG1 . ILE C 2 232 ? 231.463 201.456 291.515 1.00 60.74  ? 471 ILE G CG1 1 
ATOM   5544 C CG2 . ILE C 2 232 ? 229.248 201.483 290.356 1.00 57.77  ? 471 ILE G CG2 1 
ATOM   5545 C CD1 . ILE C 2 232 ? 232.436 200.696 290.660 1.00 59.94  ? 471 ILE G CD1 1 
ATOM   5546 N N   . CYS C 2 233 ? 227.005 200.688 293.240 1.00 49.59  ? 472 CYS G N   1 
ATOM   5547 C CA  . CYS C 2 233 ? 225.867 199.838 293.546 1.00 52.70  ? 472 CYS G CA  1 
ATOM   5548 C C   . CYS C 2 233 ? 225.424 199.097 292.294 1.00 62.57  ? 472 CYS G C   1 
ATOM   5549 O O   . CYS C 2 233 ? 225.055 199.741 291.303 1.00 57.14  ? 472 CYS G O   1 
ATOM   5550 C CB  . CYS C 2 233 ? 224.721 200.662 294.109 1.00 45.07  ? 472 CYS G CB  1 
ATOM   5551 S SG  . CYS C 2 233 ? 223.499 199.669 294.967 1.00 62.10  ? 472 CYS G SG  1 
ATOM   5552 N N   . PRO C 2 234 ? 225.445 197.766 292.286 1.00 66.32  ? 473 PRO G N   1 
ATOM   5553 C CA  . PRO C 2 234 ? 225.009 197.033 291.094 1.00 51.14  ? 473 PRO G CA  1 
ATOM   5554 C C   . PRO C 2 234 ? 223.515 197.189 290.871 1.00 55.50  ? 473 PRO G C   1 
ATOM   5555 O O   . PRO C 2 234 ? 222.741 197.348 291.817 1.00 57.77  ? 473 PRO G O   1 
ATOM   5556 C CB  . PRO C 2 234 ? 225.379 195.578 291.410 1.00 49.48  ? 473 PRO G CB  1 
ATOM   5557 C CG  . PRO C 2 234 ? 226.229 195.631 292.654 1.00 51.33  ? 473 PRO G CG  1 
ATOM   5558 C CD  . PRO C 2 234 ? 225.834 196.863 293.379 1.00 52.61  ? 473 PRO G CD  1 
ATOM   5559 N N   . ALA C 2 235 ? 223.115 197.144 289.604 1.00 51.83  ? 474 ALA G N   1 
ATOM   5560 C CA  . ALA C 2 235 ? 221.701 197.215 289.273 1.00 49.12  ? 474 ALA G CA  1 
ATOM   5561 C C   . ALA C 2 235 ? 220.971 196.012 289.851 1.00 48.44  ? 474 ALA G C   1 
ATOM   5562 O O   . ALA C 2 235 ? 221.562 194.953 290.079 1.00 53.40  ? 474 ALA G O   1 
ATOM   5563 C CB  . ALA C 2 235 ? 221.506 197.271 287.759 1.00 53.97  ? 474 ALA G CB  1 
ATOM   5564 N N   . LEU C 2 236 ? 219.679 196.191 290.114 1.00 46.72  ? 475 LEU G N   1 
ATOM   5565 C CA  . LEU C 2 236 ? 218.880 195.112 290.675 1.00 51.23  ? 475 LEU G CA  1 
ATOM   5566 C C   . LEU C 2 236 ? 218.985 193.879 289.790 1.00 51.77  ? 475 LEU G C   1 
ATOM   5567 O O   . LEU C 2 236 ? 218.521 193.881 288.646 1.00 52.97  ? 475 LEU G O   1 
ATOM   5568 C CB  . LEU C 2 236 ? 217.424 195.552 290.819 1.00 46.80  ? 475 LEU G CB  1 
ATOM   5569 C CG  . LEU C 2 236 ? 217.141 196.826 291.616 1.00 39.52  ? 475 LEU G CG  1 
ATOM   5570 C CD1 . LEU C 2 236 ? 215.665 196.924 291.949 1.00 34.97  ? 475 LEU G CD1 1 
ATOM   5571 C CD2 . LEU C 2 236 ? 217.976 196.874 292.881 1.00 49.56  ? 475 LEU G CD2 1 
ATOM   5572 N N   . THR C 2 237 ? 219.606 192.829 290.319 1.00 56.84  ? 476 THR G N   1 
ATOM   5573 C CA  . THR C 2 237 ? 219.870 191.611 289.569 1.00 55.97  ? 476 THR G CA  1 
ATOM   5574 C C   . THR C 2 237 ? 218.693 190.642 289.592 1.00 56.65  ? 476 THR G C   1 
ATOM   5575 O O   . THR C 2 237 ? 218.715 189.639 288.872 1.00 59.71  ? 476 THR G O   1 
ATOM   5576 C CB  . THR C 2 237 ? 221.128 190.927 290.114 1.00 52.28  ? 476 THR G CB  1 
ATOM   5577 O OG1 . THR C 2 237 ? 222.075 191.924 290.511 1.00 55.26  ? 476 THR G OG1 1 
ATOM   5578 C CG2 . THR C 2 237 ? 221.772 190.054 289.050 1.00 53.60  ? 476 THR G CG2 1 
ATOM   5579 N N   . GLY C 2 238 ? 217.664 190.924 290.383 1.00 58.54  ? 477 GLY G N   1 
ATOM   5580 C CA  . GLY C 2 238 ? 216.542 190.005 290.463 1.00 60.11  ? 477 GLY G CA  1 
ATOM   5581 C C   . GLY C 2 238 ? 216.978 188.714 291.119 1.00 69.78  ? 477 GLY G C   1 
ATOM   5582 O O   . GLY C 2 238 ? 217.932 188.682 291.903 1.00 74.31  ? 477 GLY G O   1 
ATOM   5583 N N   . ALA C 2 239 ? 216.279 187.626 290.801 1.00 68.29  ? 478 ALA G N   1 
ATOM   5584 C CA  . ALA C 2 239 ? 216.648 186.311 291.305 1.00 65.74  ? 478 ALA G CA  1 
ATOM   5585 C C   . ALA C 2 239 ? 217.133 185.408 290.180 1.00 67.55  ? 478 ALA G C   1 
ATOM   5586 O O   . ALA C 2 239 ? 217.011 184.184 290.262 1.00 76.25  ? 478 ALA G O   1 
ATOM   5587 C CB  . ALA C 2 239 ? 215.488 185.656 292.051 1.00 63.73  ? 478 ALA G CB  1 
ATOM   5588 N N   . ASN C 2 240 ? 217.671 185.995 289.117 1.00 63.36  ? 479 ASN G N   1 
ATOM   5589 C CA  . ASN C 2 240 ? 218.274 185.188 288.070 1.00 68.01  ? 479 ASN G CA  1 
ATOM   5590 C C   . ASN C 2 240 ? 219.578 184.568 288.564 1.00 68.72  ? 479 ASN G C   1 
ATOM   5591 O O   . ASN C 2 240 ? 220.249 185.097 289.453 1.00 60.74  ? 479 ASN G O   1 
ATOM   5592 C CB  . ASN C 2 240 ? 218.428 186.022 286.780 1.00 63.96  ? 479 ASN G CB  1 
ATOM   5593 C CG  . ASN C 2 240 ? 219.744 186.823 286.675 1.00 70.19  ? 479 ASN G CG  1 
ATOM   5594 O OD1 . ASN C 2 240 ? 220.721 186.614 287.387 1.00 68.63  ? 479 ASN G OD1 1 
ATOM   5595 N ND2 . ASN C 2 240 ? 219.744 187.769 285.744 1.00 75.32  ? 479 ASN G ND2 1 
ATOM   5596 N N   . GLY C 2 241 ? 219.904 183.402 288.012 1.00 72.93  ? 480 GLY G N   1 
ATOM   5597 C CA  . GLY C 2 241 ? 221.107 182.692 288.385 1.00 71.91  ? 480 GLY G CA  1 
ATOM   5598 C C   . GLY C 2 241 ? 221.016 181.886 289.660 1.00 71.13  ? 480 GLY G C   1 
ATOM   5599 O O   . GLY C 2 241 ? 222.002 181.234 290.028 1.00 71.63  ? 480 GLY G O   1 
ATOM   5600 N N   . VAL C 2 242 ? 219.878 181.902 290.350 1.00 64.61  ? 481 VAL G N   1 
ATOM   5601 C CA  . VAL C 2 242 ? 219.691 181.135 291.576 1.00 64.86  ? 481 VAL G CA  1 
ATOM   5602 C C   . VAL C 2 242 ? 218.343 180.431 291.520 1.00 63.73  ? 481 VAL G C   1 
ATOM   5603 O O   . VAL C 2 242 ? 217.325 181.039 291.172 1.00 58.39  ? 481 VAL G O   1 
ATOM   5604 C CB  . VAL C 2 242 ? 219.795 182.024 292.833 1.00 66.26  ? 481 VAL G CB  1 
ATOM   5605 C CG1 . VAL C 2 242 ? 221.240 182.421 293.076 1.00 69.47  ? 481 VAL G CG1 1 
ATOM   5606 C CG2 . VAL C 2 242 ? 218.925 183.259 292.692 1.00 71.24  ? 481 VAL G CG2 1 
ATOM   5607 N N   . THR C 2 243 ? 218.342 179.144 291.855 1.00 70.69  ? 482 THR G N   1 
ATOM   5608 C CA  . THR C 2 243 ? 217.132 178.335 291.835 1.00 69.39  ? 482 THR G CA  1 
ATOM   5609 C C   . THR C 2 243 ? 216.216 178.759 292.973 1.00 66.36  ? 482 THR G C   1 
ATOM   5610 O O   . THR C 2 243 ? 216.663 178.913 294.114 1.00 64.61  ? 482 THR G O   1 
ATOM   5611 C CB  . THR C 2 243 ? 217.473 176.849 291.953 1.00 69.36  ? 482 THR G CB  1 
ATOM   5612 O OG1 . THR C 2 243 ? 218.251 176.445 290.819 1.00 68.89  ? 482 THR G OG1 1 
ATOM   5613 C CG2 . THR C 2 243 ? 216.206 176.013 292.010 1.00 66.62  ? 482 THR G CG2 1 
ATOM   5614 N N   . VAL C 2 244 ? 214.937 178.943 292.660 1.00 69.62  ? 483 VAL G N   1 
ATOM   5615 C CA  . VAL C 2 244 ? 213.945 179.404 293.627 1.00 69.47  ? 483 VAL G CA  1 
ATOM   5616 C C   . VAL C 2 244 ? 213.152 178.186 294.098 1.00 71.67  ? 483 VAL G C   1 
ATOM   5617 O O   . VAL C 2 244 ? 212.392 177.613 293.302 1.00 73.13  ? 483 VAL G O   1 
ATOM   5618 C CB  . VAL C 2 244 ? 213.019 180.464 293.022 1.00 65.90  ? 483 VAL G CB  1 
ATOM   5619 C CG1 . VAL C 2 244 ? 212.153 181.084 294.103 1.00 66.05  ? 483 VAL G CG1 1 
ATOM   5620 C CG2 . VAL C 2 244 ? 213.833 181.527 292.307 1.00 69.80  ? 483 VAL G CG2 1 
ATOM   5621 N N   . PRO C 2 245 ? 213.297 177.761 295.349 1.00 75.22  ? 484 PRO G N   1 
ATOM   5622 C CA  . PRO C 2 245 ? 212.437 176.692 295.863 1.00 73.20  ? 484 PRO G CA  1 
ATOM   5623 C C   . PRO C 2 245 ? 210.983 177.131 295.894 1.00 75.45  ? 484 PRO G C   1 
ATOM   5624 O O   . PRO C 2 245 ? 210.669 178.316 296.027 1.00 74.87  ? 484 PRO G O   1 
ATOM   5625 C CB  . PRO C 2 245 ? 212.975 176.448 297.278 1.00 73.35  ? 484 PRO G CB  1 
ATOM   5626 C CG  . PRO C 2 245 ? 214.360 177.008 297.267 1.00 71.49  ? 484 PRO G CG  1 
ATOM   5627 C CD  . PRO C 2 245 ? 214.316 178.171 296.328 1.00 74.16  ? 484 PRO G CD  1 
ATOM   5628 N N   . GLU C 2 246 ? 210.087 176.148 295.761 1.00 83.35  ? 485 GLU G N   1 
ATOM   5629 C CA  . GLU C 2 246 ? 208.659 176.445 295.736 1.00 83.50  ? 485 GLU G CA  1 
ATOM   5630 C C   . GLU C 2 246 ? 208.203 177.133 297.014 1.00 84.80  ? 485 GLU G C   1 
ATOM   5631 O O   . GLU C 2 246 ? 207.179 177.826 297.014 1.00 85.44  ? 485 GLU G O   1 
ATOM   5632 C CB  . GLU C 2 246 ? 207.859 175.163 295.513 1.00 84.44  ? 485 GLU G CB  1 
ATOM   5633 C CG  . GLU C 2 246 ? 207.812 174.712 294.067 1.00 86.28  ? 485 GLU G CG  1 
ATOM   5634 C CD  . GLU C 2 246 ? 206.811 175.496 293.248 1.00 87.70  ? 485 GLU G CD  1 
ATOM   5635 O OE1 . GLU C 2 246 ? 206.051 176.291 293.838 1.00 84.88  ? 485 GLU G OE1 1 
ATOM   5636 O OE2 . GLU C 2 246 ? 206.784 175.318 292.013 1.00 91.25  ? 485 GLU G OE2 1 
ATOM   5637 N N   . GLU C 2 247 ? 208.941 176.951 298.111 1.00 84.13  ? 486 GLU G N   1 
ATOM   5638 C CA  . GLU C 2 247 ? 208.642 177.689 299.332 1.00 83.33  ? 486 GLU G CA  1 
ATOM   5639 C C   . GLU C 2 247 ? 208.790 179.188 299.119 1.00 86.29  ? 486 GLU G C   1 
ATOM   5640 O O   . GLU C 2 247 ? 208.121 179.983 299.790 1.00 88.05  ? 486 GLU G O   1 
ATOM   5641 C CB  . GLU C 2 247 ? 209.551 177.209 300.464 1.00 84.16  ? 486 GLU G CB  1 
ATOM   5642 C CG  . GLU C 2 247 ? 209.382 177.956 301.774 1.00 86.93  ? 486 GLU G CG  1 
ATOM   5643 C CD  . GLU C 2 247 ? 207.946 177.972 302.252 1.00 88.49  ? 486 GLU G CD  1 
ATOM   5644 O OE1 . GLU C 2 247 ? 207.368 176.881 302.438 1.00 88.69  ? 486 GLU G OE1 1 
ATOM   5645 O OE2 . GLU C 2 247 ? 207.395 179.074 302.441 1.00 84.87  ? 486 GLU G OE2 1 
ATOM   5646 N N   . GLY C 2 248 ? 209.642 179.592 298.181 1.00 78.24  ? 487 GLY G N   1 
ATOM   5647 C CA  . GLY C 2 248 ? 209.834 180.995 297.884 1.00 76.31  ? 487 GLY G CA  1 
ATOM   5648 C C   . GLY C 2 248 ? 211.127 181.532 298.454 1.00 73.80  ? 487 GLY G C   1 
ATOM   5649 O O   . GLY C 2 248 ? 211.272 181.645 299.675 1.00 77.95  ? 487 GLY G O   1 
ATOM   5650 N N   . LEU C 2 249 ? 212.075 181.859 297.581 1.00 68.23  ? 488 LEU G N   1 
ATOM   5651 C CA  . LEU C 2 249 ? 213.369 182.353 298.029 1.00 70.40  ? 488 LEU G CA  1 
ATOM   5652 C C   . LEU C 2 249 ? 213.193 183.660 298.788 1.00 77.44  ? 488 LEU G C   1 
ATOM   5653 O O   . LEU C 2 249 ? 212.678 184.641 298.242 1.00 78.44  ? 488 LEU G O   1 
ATOM   5654 C CB  . LEU C 2 249 ? 214.294 182.544 296.831 1.00 66.14  ? 488 LEU G CB  1 
ATOM   5655 C CG  . LEU C 2 249 ? 215.671 183.141 297.108 1.00 66.05  ? 488 LEU G CG  1 
ATOM   5656 C CD1 . LEU C 2 249 ? 216.354 182.414 298.250 1.00 62.88  ? 488 LEU G CD1 1 
ATOM   5657 C CD2 . LEU C 2 249 ? 216.514 183.077 295.852 1.00 69.04  ? 488 LEU G CD2 1 
ATOM   5658 N N   . THR C 2 250 ? 213.622 183.674 300.047 1.00 77.42  ? 489 THR G N   1 
ATOM   5659 C CA  . THR C 2 250 ? 213.376 184.794 300.940 1.00 72.91  ? 489 THR G CA  1 
ATOM   5660 C C   . THR C 2 250 ? 214.671 185.247 301.597 1.00 71.53  ? 489 THR G C   1 
ATOM   5661 O O   . THR C 2 250 ? 215.494 184.430 302.017 1.00 71.46  ? 489 THR G O   1 
ATOM   5662 C CB  . THR C 2 250 ? 212.345 184.429 302.016 1.00 70.38  ? 489 THR G CB  1 
ATOM   5663 O OG1 . THR C 2 250 ? 212.335 185.434 303.035 1.00 75.48  ? 489 THR G OG1 1 
ATOM   5664 C CG2 . THR C 2 250 ? 212.674 183.081 302.637 1.00 69.41  ? 489 THR G CG2 1 
ATOM   5665 N N   . LEU C 2 251 ? 214.838 186.569 301.673 1.00 75.28  ? 490 LEU G N   1 
ATOM   5666 C CA  . LEU C 2 251 ? 215.975 187.202 302.344 1.00 78.25  ? 490 LEU G CA  1 
ATOM   5667 C C   . LEU C 2 251 ? 217.305 186.689 301.790 1.00 80.35  ? 490 LEU G C   1 
ATOM   5668 O O   . LEU C 2 251 ? 218.215 186.317 302.533 1.00 80.50  ? 490 LEU G O   1 
ATOM   5669 C CB  . LEU C 2 251 ? 215.896 187.006 303.860 1.00 81.31  ? 490 LEU G CB  1 
ATOM   5670 C CG  . LEU C 2 251 ? 215.116 188.049 304.671 1.00 81.82  ? 490 LEU G CG  1 
ATOM   5671 C CD1 . LEU C 2 251 ? 215.721 189.434 304.524 1.00 75.07  ? 490 LEU G CD1 1 
ATOM   5672 C CD2 . LEU C 2 251 ? 213.643 188.069 304.293 1.00 81.39  ? 490 LEU G CD2 1 
ATOM   5673 N N   . HIS C 2 252 ? 217.408 186.673 300.465 1.00 76.90  ? 491 HIS G N   1 
ATOM   5674 C CA  . HIS C 2 252 ? 218.614 186.222 299.782 1.00 71.24  ? 491 HIS G CA  1 
ATOM   5675 C C   . HIS C 2 252 ? 219.759 187.193 300.049 1.00 78.99  ? 491 HIS G C   1 
ATOM   5676 O O   . HIS C 2 252 ? 219.558 188.411 300.057 1.00 87.88  ? 491 HIS G O   1 
ATOM   5677 C CB  . HIS C 2 252 ? 218.347 186.110 298.283 1.00 74.56  ? 491 HIS G CB  1 
ATOM   5678 C CG  . HIS C 2 252 ? 219.377 185.322 297.535 1.00 75.69  ? 491 HIS G CG  1 
ATOM   5679 N ND1 . HIS C 2 252 ? 219.185 184.895 296.239 1.00 77.75  ? 491 HIS G ND1 1 
ATOM   5680 C CD2 . HIS C 2 252 ? 220.602 184.876 297.900 1.00 79.16  ? 491 HIS G CD2 1 
ATOM   5681 C CE1 . HIS C 2 252 ? 220.249 184.225 295.836 1.00 77.91  ? 491 HIS G CE1 1 
ATOM   5682 N NE2 . HIS C 2 252 ? 221.124 184.200 296.825 1.00 81.91  ? 491 HIS G NE2 1 
ATOM   5683 N N   . ARG C 2 253 ? 220.954 186.656 300.269 1.00 74.79  ? 492 ARG G N   1 
ATOM   5684 C CA  . ARG C 2 253 ? 222.168 187.468 300.324 1.00 77.54  ? 492 ARG G CA  1 
ATOM   5685 C C   . ARG C 2 253 ? 222.980 187.326 299.042 1.00 72.50  ? 492 ARG G C   1 
ATOM   5686 O O   . ARG C 2 253 ? 223.741 186.373 298.879 1.00 66.90  ? 492 ARG G O   1 
ATOM   5687 C CB  . ARG C 2 253 ? 223.027 187.087 301.531 1.00 76.81  ? 492 ARG G CB  1 
ATOM   5688 C CG  . ARG C 2 253 ? 222.462 187.478 302.893 1.00 78.90  ? 492 ARG G CG  1 
ATOM   5689 C CD  . ARG C 2 253 ? 221.374 188.534 302.795 1.00 79.28  ? 492 ARG G CD  1 
ATOM   5690 N NE  . ARG C 2 253 ? 220.653 188.687 304.052 1.00 86.56  ? 492 ARG G NE  1 
ATOM   5691 C CZ  . ARG C 2 253 ? 219.376 189.028 304.147 1.00 82.81  ? 492 ARG G CZ  1 
ATOM   5692 N NH1 . ARG C 2 253 ? 218.642 189.267 303.073 1.00 77.86  ? 492 ARG G NH1 1 
ATOM   5693 N NH2 . ARG C 2 253 ? 218.823 189.136 305.352 1.00 81.12  ? 492 ARG G NH2 1 
ATOM   5694 N N   . TRP D 2 1   ? 209.920 202.188 193.235 1.00 120.60 ? 240 TRP E N   1 
ATOM   5695 C CA  . TRP D 2 1   ? 209.929 201.307 194.397 1.00 123.10 ? 240 TRP E CA  1 
ATOM   5696 C C   . TRP D 2 1   ? 211.036 201.693 195.370 1.00 123.51 ? 240 TRP E C   1 
ATOM   5697 O O   . TRP D 2 1   ? 210.846 201.654 196.584 1.00 124.13 ? 240 TRP E O   1 
ATOM   5698 C CB  . TRP D 2 1   ? 210.093 199.850 193.964 1.00 123.06 ? 240 TRP E CB  1 
ATOM   5699 N N   . ILE D 2 2   ? 212.188 202.081 194.817 1.00 130.21 ? 241 ILE E N   1 
ATOM   5700 C CA  . ILE D 2 2   ? 213.360 202.393 195.631 1.00 132.78 ? 241 ILE E CA  1 
ATOM   5701 C C   . ILE D 2 2   ? 213.090 203.567 196.562 1.00 132.70 ? 241 ILE E C   1 
ATOM   5702 O O   . ILE D 2 2   ? 213.473 203.538 197.741 1.00 132.94 ? 241 ILE E O   1 
ATOM   5703 C CB  . ILE D 2 2   ? 214.570 202.671 194.718 1.00 131.34 ? 241 ILE E CB  1 
ATOM   5704 C CG1 . ILE D 2 2   ? 215.073 201.376 194.077 1.00 129.95 ? 241 ILE E CG1 1 
ATOM   5705 C CG2 . ILE D 2 2   ? 215.688 203.357 195.492 1.00 130.40 ? 241 ILE E CG2 1 
ATOM   5706 C CD1 . ILE D 2 2   ? 215.856 200.496 195.019 1.00 128.02 ? 241 ILE E CD1 1 
ATOM   5707 N N   . ASN D 2 3   ? 212.431 204.611 196.059 1.00 133.23 ? 242 ASN E N   1 
ATOM   5708 C CA  . ASN D 2 3   ? 212.307 205.850 196.818 1.00 133.45 ? 242 ASN E CA  1 
ATOM   5709 C C   . ASN D 2 3   ? 211.524 205.648 198.112 1.00 133.04 ? 242 ASN E C   1 
ATOM   5710 O O   . ASN D 2 3   ? 212.010 205.984 199.199 1.00 132.09 ? 242 ASN E O   1 
ATOM   5711 C CB  . ASN D 2 3   ? 211.662 206.925 195.943 1.00 134.69 ? 242 ASN E CB  1 
ATOM   5712 C CG  . ASN D 2 3   ? 210.567 206.371 195.054 1.00 134.41 ? 242 ASN E CG  1 
ATOM   5713 O OD1 . ASN D 2 3   ? 209.796 205.507 195.464 1.00 134.66 ? 242 ASN E OD1 1 
ATOM   5714 N ND2 . ASN D 2 3   ? 210.497 206.868 193.824 1.00 131.17 ? 242 ASN E ND2 1 
ATOM   5715 N N   . LYS D 2 4   ? 210.315 205.087 198.020 1.00 133.33 ? 243 LYS E N   1 
ATOM   5716 C CA  . LYS D 2 4   ? 209.508 204.906 199.225 1.00 133.46 ? 243 LYS E CA  1 
ATOM   5717 C C   . LYS D 2 4   ? 210.131 203.887 200.170 1.00 133.05 ? 243 LYS E C   1 
ATOM   5718 O O   . LYS D 2 4   ? 210.057 204.042 201.396 1.00 133.82 ? 243 LYS E O   1 
ATOM   5719 C CB  . LYS D 2 4   ? 208.075 204.506 198.865 1.00 133.31 ? 243 LYS E CB  1 
ATOM   5720 C CG  . LYS D 2 4   ? 207.571 205.051 197.540 1.00 132.81 ? 243 LYS E CG  1 
ATOM   5721 C CD  . LYS D 2 4   ? 206.529 204.141 196.913 1.00 132.42 ? 243 LYS E CD  1 
ATOM   5722 C CE  . LYS D 2 4   ? 207.174 203.098 196.025 1.00 132.01 ? 243 LYS E CE  1 
ATOM   5723 N NZ  . LYS D 2 4   ? 207.833 203.741 194.856 1.00 131.98 ? 243 LYS E NZ  1 
ATOM   5724 N N   . LEU D 2 5   ? 210.760 202.843 199.630 1.00 131.04 ? 244 LEU E N   1 
ATOM   5725 C CA  . LEU D 2 5   ? 211.371 201.853 200.509 1.00 130.68 ? 244 LEU E CA  1 
ATOM   5726 C C   . LEU D 2 5   ? 212.542 202.456 201.275 1.00 131.56 ? 244 LEU E C   1 
ATOM   5727 O O   . LEU D 2 5   ? 212.797 202.091 202.427 1.00 133.78 ? 244 LEU E O   1 
ATOM   5728 C CB  . LEU D 2 5   ? 211.798 200.606 199.726 1.00 131.44 ? 244 LEU E CB  1 
ATOM   5729 C CG  . LEU D 2 5   ? 212.980 200.563 198.756 1.00 132.94 ? 244 LEU E CG  1 
ATOM   5730 C CD1 . LEU D 2 5   ? 214.283 200.341 199.500 1.00 130.82 ? 244 LEU E CD1 1 
ATOM   5731 C CD2 . LEU D 2 5   ? 212.771 199.454 197.738 1.00 133.31 ? 244 LEU E CD2 1 
ATOM   5732 N N   . GLN D 2 6   ? 213.271 203.394 200.664 1.00 127.19 ? 245 GLN E N   1 
ATOM   5733 C CA  . GLN D 2 6   ? 214.411 203.952 201.384 1.00 127.34 ? 245 GLN E CA  1 
ATOM   5734 C C   . GLN D 2 6   ? 213.954 205.070 202.323 1.00 129.53 ? 245 GLN E C   1 
ATOM   5735 O O   . GLN D 2 6   ? 214.585 205.317 203.359 1.00 129.44 ? 245 GLN E O   1 
ATOM   5736 C CB  . GLN D 2 6   ? 215.509 204.384 200.395 1.00 126.95 ? 245 GLN E CB  1 
ATOM   5737 C CG  . GLN D 2 6   ? 215.508 205.765 199.732 1.00 128.78 ? 245 GLN E CG  1 
ATOM   5738 C CD  . GLN D 2 6   ? 215.628 206.910 200.717 1.00 129.19 ? 245 GLN E CD  1 
ATOM   5739 O OE1 . GLN D 2 6   ? 216.498 206.899 201.587 1.00 129.77 ? 245 GLN E OE1 1 
ATOM   5740 N NE2 . GLN D 2 6   ? 214.803 207.924 200.552 1.00 128.84 ? 245 GLN E NE2 1 
ATOM   5741 N N   . LYS D 2 7   ? 212.820 205.719 202.010 1.00 126.67 ? 246 LYS E N   1 
ATOM   5742 C CA  . LYS D 2 7   ? 212.097 206.445 203.059 1.00 124.53 ? 246 LYS E CA  1 
ATOM   5743 C C   . LYS D 2 7   ? 211.824 205.551 204.260 1.00 123.81 ? 246 LYS E C   1 
ATOM   5744 O O   . LYS D 2 7   ? 212.053 205.952 205.406 1.00 123.17 ? 246 LYS E O   1 
ATOM   5745 C CB  . LYS D 2 7   ? 210.762 207.021 202.564 1.00 124.89 ? 246 LYS E CB  1 
ATOM   5746 C CG  . LYS D 2 7   ? 210.685 207.781 201.248 1.00 125.32 ? 246 LYS E CG  1 
ATOM   5747 C CD  . LYS D 2 7   ? 211.889 208.661 201.009 1.00 125.09 ? 246 LYS E CD  1 
ATOM   5748 C CE  . LYS D 2 7   ? 211.885 209.242 199.602 1.00 126.08 ? 246 LYS E CE  1 
ATOM   5749 N NZ  . LYS D 2 7   ? 212.723 208.479 198.647 1.00 126.06 ? 246 LYS E NZ  1 
ATOM   5750 N N   . GLU D 2 8   ? 211.303 204.347 204.017 1.00 124.72 ? 247 GLU E N   1 
ATOM   5751 C CA  . GLU D 2 8   ? 210.980 203.445 205.119 1.00 124.19 ? 247 GLU E CA  1 
ATOM   5752 C C   . GLU D 2 8   ? 212.233 203.043 205.888 1.00 124.51 ? 247 GLU E C   1 
ATOM   5753 O O   . GLU D 2 8   ? 212.208 202.942 207.119 1.00 125.83 ? 247 GLU E O   1 
ATOM   5754 C CB  . GLU D 2 8   ? 210.248 202.210 204.590 1.00 124.53 ? 247 GLU E CB  1 
ATOM   5755 C CG  . GLU D 2 8   ? 210.228 201.028 205.550 1.00 124.34 ? 247 GLU E CG  1 
ATOM   5756 C CD  . GLU D 2 8   ? 211.281 199.984 205.227 1.00 126.12 ? 247 GLU E CD  1 
ATOM   5757 O OE1 . GLU D 2 8   ? 212.048 200.185 204.264 1.00 126.50 ? 247 GLU E OE1 1 
ATOM   5758 O OE2 . GLU D 2 8   ? 211.341 198.961 205.940 1.00 126.22 ? 247 GLU E OE2 1 
ATOM   5759 N N   . LYS D 2 9   ? 213.333 202.798 205.175 1.00 117.97 ? 248 LYS E N   1 
ATOM   5760 C CA  . LYS D 2 9   ? 214.588 202.453 205.838 1.00 114.82 ? 248 LYS E CA  1 
ATOM   5761 C C   . LYS D 2 9   ? 215.081 203.593 206.722 1.00 117.25 ? 248 LYS E C   1 
ATOM   5762 O O   . LYS D 2 9   ? 215.503 203.364 207.864 1.00 120.35 ? 248 LYS E O   1 
ATOM   5763 C CB  . LYS D 2 9   ? 215.647 202.083 204.801 1.00 114.98 ? 248 LYS E CB  1 
ATOM   5764 N N   . LYS D 2 10  ? 215.031 204.829 206.215 1.00 114.62 ? 249 LYS E N   1 
ATOM   5765 C CA  . LYS D 2 10  ? 215.410 205.973 207.036 1.00 114.25 ? 249 LYS E CA  1 
ATOM   5766 C C   . LYS D 2 10  ? 214.490 206.121 208.241 1.00 116.75 ? 249 LYS E C   1 
ATOM   5767 O O   . LYS D 2 10  ? 214.955 206.425 209.344 1.00 113.46 ? 249 LYS E O   1 
ATOM   5768 C CB  . LYS D 2 10  ? 215.401 207.250 206.197 1.00 110.70 ? 249 LYS E CB  1 
ATOM   5769 N N   . ILE D 2 11  ? 213.189 205.890 208.057 1.00 131.14 ? 250 ILE E N   1 
ATOM   5770 C CA  . ILE D 2 11  ? 212.248 205.983 209.170 1.00 131.75 ? 250 ILE E CA  1 
ATOM   5771 C C   . ILE D 2 11  ? 212.578 204.948 210.238 1.00 130.92 ? 250 ILE E C   1 
ATOM   5772 O O   . ILE D 2 11  ? 212.591 205.252 211.437 1.00 131.72 ? 250 ILE E O   1 
ATOM   5773 C CB  . ILE D 2 11  ? 210.803 205.829 208.659 1.00 133.33 ? 250 ILE E CB  1 
ATOM   5774 C CG1 . ILE D 2 11  ? 210.320 207.134 208.024 1.00 132.42 ? 250 ILE E CG1 1 
ATOM   5775 C CG2 . ILE D 2 11  ? 209.872 205.404 209.788 1.00 130.15 ? 250 ILE E CG2 1 
ATOM   5776 C CD1 . ILE D 2 11  ? 209.313 206.935 206.913 1.00 130.50 ? 250 ILE E CD1 1 
ATOM   5777 N N   . LEU D 2 12  ? 212.854 203.710 209.821 1.00 119.48 ? 251 LEU E N   1 
ATOM   5778 C CA  . LEU D 2 12  ? 213.179 202.656 210.777 1.00 116.40 ? 251 LEU E CA  1 
ATOM   5779 C C   . LEU D 2 12  ? 214.467 202.975 211.526 1.00 117.76 ? 251 LEU E C   1 
ATOM   5780 O O   . LEU D 2 12  ? 214.547 202.789 212.750 1.00 121.82 ? 251 LEU E O   1 
ATOM   5781 C CB  . LEU D 2 12  ? 213.266 201.310 210.052 1.00 118.36 ? 251 LEU E CB  1 
ATOM   5782 C CG  . LEU D 2 12  ? 213.779 200.051 210.759 1.00 120.63 ? 251 LEU E CG  1 
ATOM   5783 C CD1 . LEU D 2 12  ? 213.162 198.821 210.114 1.00 117.82 ? 251 LEU E CD1 1 
ATOM   5784 C CD2 . LEU D 2 12  ? 215.293 199.947 210.701 1.00 119.68 ? 251 LEU E CD2 1 
ATOM   5785 N N   . SER D 2 13  ? 215.484 203.464 210.809 1.00 114.71 ? 252 SER E N   1 
ATOM   5786 C CA  . SER D 2 13  ? 216.693 203.932 211.477 1.00 116.50 ? 252 SER E CA  1 
ATOM   5787 C C   . SER D 2 13  ? 216.380 205.077 212.432 1.00 120.35 ? 252 SER E C   1 
ATOM   5788 O O   . SER D 2 13  ? 217.090 205.284 213.423 1.00 122.76 ? 252 SER E O   1 
ATOM   5789 C CB  . SER D 2 13  ? 217.731 204.365 210.444 1.00 117.32 ? 252 SER E CB  1 
ATOM   5790 O OG  . SER D 2 13  ? 218.761 205.127 211.049 1.00 118.89 ? 252 SER E OG  1 
ATOM   5791 N N   . GLY D 2 14  ? 215.323 205.832 212.145 1.00 121.14 ? 253 GLY E N   1 
ATOM   5792 C CA  . GLY D 2 14  ? 214.886 206.905 213.014 1.00 121.37 ? 253 GLY E CA  1 
ATOM   5793 C C   . GLY D 2 14  ? 214.489 206.456 214.406 1.00 120.92 ? 253 GLY E C   1 
ATOM   5794 O O   . GLY D 2 14  ? 214.818 207.127 215.387 1.00 119.75 ? 253 GLY E O   1 
ATOM   5795 N N   . GLU D 2 15  ? 213.775 205.338 214.518 1.00 120.87 ? 254 GLU E N   1 
ATOM   5796 C CA  . GLU D 2 15  ? 213.382 204.839 215.828 1.00 118.77 ? 254 GLU E CA  1 
ATOM   5797 C C   . GLU D 2 15  ? 214.392 203.867 216.422 1.00 119.73 ? 254 GLU E C   1 
ATOM   5798 O O   . GLU D 2 15  ? 214.378 203.656 217.641 1.00 122.93 ? 254 GLU E O   1 
ATOM   5799 C CB  . GLU D 2 15  ? 212.002 204.174 215.768 1.00 121.17 ? 254 GLU E CB  1 
ATOM   5800 C CG  . GLU D 2 15  ? 212.022 202.700 215.409 1.00 123.13 ? 254 GLU E CG  1 
ATOM   5801 C CD  . GLU D 2 15  ? 211.745 202.459 213.943 1.00 127.00 ? 254 GLU E CD  1 
ATOM   5802 O OE1 . GLU D 2 15  ? 211.373 203.426 213.246 1.00 127.00 ? 254 GLU E OE1 1 
ATOM   5803 O OE2 . GLU D 2 15  ? 211.897 201.306 213.488 1.00 128.18 ? 254 GLU E OE2 1 
ATOM   5804 N N   . LYS D 2 16  ? 215.272 203.279 215.605 1.00 114.71 ? 255 LYS E N   1 
ATOM   5805 C CA  . LYS D 2 16  ? 216.316 202.427 216.169 1.00 116.25 ? 255 LYS E CA  1 
ATOM   5806 C C   . LYS D 2 16  ? 217.218 203.208 217.119 1.00 116.26 ? 255 LYS E C   1 
ATOM   5807 O O   . LYS D 2 16  ? 217.570 202.716 218.199 1.00 119.70 ? 255 LYS E O   1 
ATOM   5808 C CB  . LYS D 2 16  ? 217.142 201.780 215.057 1.00 118.07 ? 255 LYS E CB  1 
ATOM   5809 C CG  . LYS D 2 16  ? 216.381 200.778 214.201 1.00 119.30 ? 255 LYS E CG  1 
ATOM   5810 C CD  . LYS D 2 16  ? 215.372 199.987 215.022 1.00 116.09 ? 255 LYS E CD  1 
ATOM   5811 C CE  . LYS D 2 16  ? 216.012 198.755 215.642 1.00 113.75 ? 255 LYS E CE  1 
ATOM   5812 N NZ  . LYS D 2 16  ? 214.999 197.832 216.220 1.00 110.70 ? 255 LYS E NZ  1 
ATOM   5813 N N   . GLU D 2 17  ? 217.597 204.430 216.740 1.00 117.14 ? 256 GLU E N   1 
ATOM   5814 C CA  . GLU D 2 17  ? 218.456 205.233 217.603 1.00 120.23 ? 256 GLU E CA  1 
ATOM   5815 C C   . GLU D 2 17  ? 217.767 205.611 218.909 1.00 121.97 ? 256 GLU E C   1 
ATOM   5816 O O   . GLU D 2 17  ? 218.413 205.614 219.963 1.00 120.15 ? 256 GLU E O   1 
ATOM   5817 C CB  . GLU D 2 17  ? 218.925 206.490 216.868 1.00 120.81 ? 256 GLU E CB  1 
ATOM   5818 C CG  . GLU D 2 17  ? 217.812 207.327 216.266 1.00 120.78 ? 256 GLU E CG  1 
ATOM   5819 C CD  . GLU D 2 17  ? 217.369 208.448 217.185 1.00 122.15 ? 256 GLU E CD  1 
ATOM   5820 O OE1 . GLU D 2 17  ? 218.208 208.942 217.968 1.00 123.40 ? 256 GLU E OE1 1 
ATOM   5821 O OE2 . GLU D 2 17  ? 216.183 208.835 217.129 1.00 122.04 ? 256 GLU E OE2 1 
ATOM   5822 N N   . PHE D 2 18  ? 216.472 205.932 218.871 1.00 120.81 ? 257 PHE E N   1 
ATOM   5823 C CA  . PHE D 2 18  ? 215.769 206.279 220.101 1.00 117.96 ? 257 PHE E CA  1 
ATOM   5824 C C   . PHE D 2 18  ? 215.610 205.056 220.998 1.00 116.17 ? 257 PHE E C   1 
ATOM   5825 O O   . PHE D 2 18  ? 215.732 205.150 222.227 1.00 115.69 ? 257 PHE E O   1 
ATOM   5826 C CB  . PHE D 2 18  ? 214.417 206.917 219.768 1.00 118.70 ? 257 PHE E CB  1 
ATOM   5827 C CG  . PHE D 2 18  ? 213.362 206.729 220.826 1.00 120.05 ? 257 PHE E CG  1 
ATOM   5828 C CD1 . PHE D 2 18  ? 212.538 205.614 220.829 1.00 120.23 ? 257 PHE E CD1 1 
ATOM   5829 C CD2 . PHE D 2 18  ? 213.199 207.675 221.823 1.00 119.77 ? 257 PHE E CD2 1 
ATOM   5830 C CE1 . PHE D 2 18  ? 211.572 205.454 221.804 1.00 120.87 ? 257 PHE E CE1 1 
ATOM   5831 C CE2 . PHE D 2 18  ? 212.237 207.518 222.800 1.00 121.45 ? 257 PHE E CE2 1 
ATOM   5832 C CZ  . PHE D 2 18  ? 211.423 206.405 222.791 1.00 122.56 ? 257 PHE E CZ  1 
ATOM   5833 N N   . GLU D 2 19  ? 215.353 203.892 220.396 1.00 115.66 ? 258 GLU E N   1 
ATOM   5834 C CA  . GLU D 2 19  ? 215.308 202.662 221.178 1.00 115.57 ? 258 GLU E CA  1 
ATOM   5835 C C   . GLU D 2 19  ? 216.649 202.401 221.851 1.00 116.78 ? 258 GLU E C   1 
ATOM   5836 O O   . GLU D 2 19  ? 216.700 202.025 223.028 1.00 118.78 ? 258 GLU E O   1 
ATOM   5837 C CB  . GLU D 2 19  ? 214.912 201.487 220.286 1.00 118.71 ? 258 GLU E CB  1 
ATOM   5838 C CG  . GLU D 2 19  ? 213.437 201.453 219.916 1.00 120.69 ? 258 GLU E CG  1 
ATOM   5839 C CD  . GLU D 2 19  ? 212.525 201.439 221.126 1.00 120.35 ? 258 GLU E CD  1 
ATOM   5840 O OE1 . GLU D 2 19  ? 212.405 200.380 221.774 1.00 121.18 ? 258 GLU E OE1 1 
ATOM   5841 O OE2 . GLU D 2 19  ? 211.922 202.487 221.427 1.00 117.65 ? 258 GLU E OE2 1 
ATOM   5842 N N   . ARG D 2 20  ? 217.748 202.609 221.121 1.00 120.97 ? 259 ARG E N   1 
ATOM   5843 C CA  . ARG D 2 20  ? 219.073 202.489 221.721 1.00 120.95 ? 259 ARG E CA  1 
ATOM   5844 C C   . ARG D 2 20  ? 219.276 203.478 222.860 1.00 120.88 ? 259 ARG E C   1 
ATOM   5845 O O   . ARG D 2 20  ? 219.799 203.106 223.917 1.00 122.89 ? 259 ARG E O   1 
ATOM   5846 C CB  . ARG D 2 20  ? 220.151 202.693 220.655 1.00 121.83 ? 259 ARG E CB  1 
ATOM   5847 C CG  . ARG D 2 20  ? 220.492 201.480 219.788 1.00 121.68 ? 259 ARG E CG  1 
ATOM   5848 C CD  . ARG D 2 20  ? 220.638 200.185 220.584 1.00 123.07 ? 259 ARG E CD  1 
ATOM   5849 N NE  . ARG D 2 20  ? 219.375 199.512 220.860 1.00 124.15 ? 259 ARG E NE  1 
ATOM   5850 C CZ  . ARG D 2 20  ? 219.267 198.398 221.570 1.00 122.20 ? 259 ARG E CZ  1 
ATOM   5851 N NH1 . ARG D 2 20  ? 220.325 197.827 222.120 1.00 121.33 ? 259 ARG E NH1 1 
ATOM   5852 N NH2 . ARG D 2 20  ? 218.070 197.845 221.733 1.00 119.80 ? 259 ARG E NH2 1 
ATOM   5853 N N   . GLU D 2 21  ? 218.877 204.734 222.669 1.00 117.23 ? 260 GLU E N   1 
ATOM   5854 C CA  . GLU D 2 21  ? 219.088 205.759 223.683 1.00 119.76 ? 260 GLU E CA  1 
ATOM   5855 C C   . GLU D 2 21  ? 218.184 205.593 224.898 1.00 120.79 ? 260 GLU E C   1 
ATOM   5856 O O   . GLU D 2 21  ? 218.440 206.222 225.930 1.00 119.43 ? 260 GLU E O   1 
ATOM   5857 C CB  . GLU D 2 21  ? 218.892 207.149 223.073 1.00 119.36 ? 260 GLU E CB  1 
ATOM   5858 C CG  . GLU D 2 21  ? 217.469 207.675 223.139 1.00 121.30 ? 260 GLU E CG  1 
ATOM   5859 C CD  . GLU D 2 21  ? 217.190 208.727 222.085 1.00 122.66 ? 260 GLU E CD  1 
ATOM   5860 O OE1 . GLU D 2 21  ? 218.153 209.199 221.445 1.00 123.81 ? 260 GLU E OE1 1 
ATOM   5861 O OE2 . GLU D 2 21  ? 216.008 209.083 221.895 1.00 122.75 ? 260 GLU E OE2 1 
ATOM   5862 N N   . THR D 2 22  ? 217.138 204.778 224.805 1.00 111.80 ? 261 THR E N   1 
ATOM   5863 C CA  . THR D 2 22  ? 216.278 204.515 225.952 1.00 106.59 ? 261 THR E CA  1 
ATOM   5864 C C   . THR D 2 22  ? 216.827 203.443 226.889 1.00 107.25 ? 261 THR E C   1 
ATOM   5865 O O   . THR D 2 22  ? 216.145 203.079 227.851 1.00 108.41 ? 261 THR E O   1 
ATOM   5866 C CB  . THR D 2 22  ? 214.879 204.108 225.483 1.00 108.02 ? 261 THR E CB  1 
ATOM   5867 O OG1 . THR D 2 22  ? 214.989 203.186 224.393 1.00 111.94 ? 261 THR E OG1 1 
ATOM   5868 C CG2 . THR D 2 22  ? 214.094 205.330 225.036 1.00 109.10 ? 261 THR E CG2 1 
ATOM   5869 N N   . ARG D 2 23  ? 218.034 202.929 226.639 1.00 104.90 ? 262 ARG E N   1 
ATOM   5870 C CA  . ARG D 2 23  ? 218.562 201.841 227.461 1.00 103.70 ? 262 ARG E CA  1 
ATOM   5871 C C   . ARG D 2 23  ? 219.395 202.369 228.624 1.00 106.37 ? 262 ARG E C   1 
ATOM   5872 O O   . ARG D 2 23  ? 219.333 201.838 229.744 1.00 108.78 ? 262 ARG E O   1 
ATOM   5873 C CB  . ARG D 2 23  ? 219.398 200.896 226.598 1.00 102.33 ? 262 ARG E CB  1 
ATOM   5874 C CG  . ARG D 2 23  ? 218.704 200.395 225.343 1.00 106.37 ? 262 ARG E CG  1 
ATOM   5875 C CD  . ARG D 2 23  ? 217.341 199.799 225.647 1.00 107.33 ? 262 ARG E CD  1 
ATOM   5876 N NE  . ARG D 2 23  ? 217.379 198.933 226.820 1.00 109.44 ? 262 ARG E NE  1 
ATOM   5877 C CZ  . ARG D 2 23  ? 216.427 198.072 227.147 1.00 108.32 ? 262 ARG E CZ  1 
ATOM   5878 N NH1 . ARG D 2 23  ? 215.365 197.893 226.380 1.00 104.35 ? 262 ARG E NH1 1 
ATOM   5879 N NH2 . ARG D 2 23  ? 216.549 197.363 228.266 1.00 106.34 ? 262 ARG E NH2 1 
ATOM   5880 N N   . GLU D 2 24  ? 220.204 203.399 228.368 1.00 112.50 ? 263 GLU E N   1 
ATOM   5881 C CA  . GLU D 2 24  ? 221.117 203.891 229.394 1.00 114.71 ? 263 GLU E CA  1 
ATOM   5882 C C   . GLU D 2 24  ? 220.361 204.495 230.569 1.00 113.74 ? 263 GLU E C   1 
ATOM   5883 O O   . GLU D 2 24  ? 220.794 204.366 231.718 1.00 111.65 ? 263 GLU E O   1 
ATOM   5884 C CB  . GLU D 2 24  ? 222.097 204.901 228.797 1.00 116.33 ? 263 GLU E CB  1 
ATOM   5885 C CG  . GLU D 2 24  ? 221.455 206.102 228.129 1.00 116.19 ? 263 GLU E CG  1 
ATOM   5886 C CD  . GLU D 2 24  ? 221.298 205.917 226.633 1.00 118.08 ? 263 GLU E CD  1 
ATOM   5887 O OE1 . GLU D 2 24  ? 221.205 206.936 225.917 1.00 118.89 ? 263 GLU E OE1 1 
ATOM   5888 O OE2 . GLU D 2 24  ? 221.269 204.757 226.173 1.00 118.52 ? 263 GLU E OE2 1 
ATOM   5889 N N   . ILE D 2 25  ? 219.232 205.156 230.306 1.00 107.66 ? 264 ILE E N   1 
ATOM   5890 C CA  . ILE D 2 25  ? 218.442 205.725 231.394 1.00 107.65 ? 264 ILE E CA  1 
ATOM   5891 C C   . ILE D 2 25  ? 217.959 204.618 232.327 1.00 105.50 ? 264 ILE E C   1 
ATOM   5892 O O   . ILE D 2 25  ? 218.074 204.722 233.555 1.00 106.81 ? 264 ILE E O   1 
ATOM   5893 C CB  . ILE D 2 25  ? 217.274 206.560 230.830 1.00 109.06 ? 264 ILE E CB  1 
ATOM   5894 C CG1 . ILE D 2 25  ? 216.397 207.129 231.952 1.00 109.05 ? 264 ILE E CG1 1 
ATOM   5895 C CG2 . ILE D 2 25  ? 216.452 205.762 229.818 1.00 107.63 ? 264 ILE E CG2 1 
ATOM   5896 C CD1 . ILE D 2 25  ? 217.170 207.770 233.091 1.00 108.51 ? 264 ILE E CD1 1 
ATOM   5897 N N   . ALA D 2 26  ? 217.440 203.528 231.755 1.00 96.57  ? 265 ALA E N   1 
ATOM   5898 C CA  . ALA D 2 26  ? 216.955 202.420 232.570 1.00 99.17  ? 265 ALA E CA  1 
ATOM   5899 C C   . ALA D 2 26  ? 218.085 201.771 233.360 1.00 101.23 ? 265 ALA E C   1 
ATOM   5900 O O   . ALA D 2 26  ? 217.929 201.481 234.554 1.00 104.23 ? 265 ALA E O   1 
ATOM   5901 C CB  . ALA D 2 26  ? 216.257 201.387 231.687 1.00 98.21  ? 265 ALA E CB  1 
ATOM   5902 N N   . LEU D 2 27  ? 219.231 201.540 232.715 1.00 104.67 ? 266 LEU E N   1 
ATOM   5903 C CA  . LEU D 2 27  ? 220.340 200.910 233.429 1.00 105.67 ? 266 LEU E CA  1 
ATOM   5904 C C   . LEU D 2 27  ? 220.851 201.806 234.553 1.00 106.52 ? 266 LEU E C   1 
ATOM   5905 O O   . LEU D 2 27  ? 221.155 201.323 235.653 1.00 108.21 ? 266 LEU E O   1 
ATOM   5906 C CB  . LEU D 2 27  ? 221.458 200.537 232.449 1.00 107.43 ? 266 LEU E CB  1 
ATOM   5907 C CG  . LEU D 2 27  ? 222.547 201.513 231.989 1.00 108.11 ? 266 LEU E CG  1 
ATOM   5908 C CD1 . LEU D 2 27  ? 223.702 201.604 232.982 1.00 107.27 ? 266 LEU E CD1 1 
ATOM   5909 C CD2 . LEU D 2 27  ? 223.060 201.106 230.617 1.00 109.00 ? 266 LEU E CD2 1 
ATOM   5910 N N   . LYS D 2 28  ? 220.941 203.114 234.299 1.00 103.45 ? 267 LYS E N   1 
ATOM   5911 C CA  . LYS D 2 28  ? 221.425 204.040 235.315 1.00 106.58 ? 267 LYS E CA  1 
ATOM   5912 C C   . LYS D 2 28  ? 220.454 204.096 236.487 1.00 106.94 ? 267 LYS E C   1 
ATOM   5913 O O   . LYS D 2 28  ? 220.872 204.119 237.650 1.00 105.01 ? 267 LYS E O   1 
ATOM   5914 C CB  . LYS D 2 28  ? 221.626 205.421 234.672 1.00 104.88 ? 267 LYS E CB  1 
ATOM   5915 C CG  . LYS D 2 28  ? 221.796 206.689 235.555 1.00 106.57 ? 267 LYS E CG  1 
ATOM   5916 C CD  . LYS D 2 28  ? 222.511 206.544 236.909 1.00 107.12 ? 267 LYS E CD  1 
ATOM   5917 C CE  . LYS D 2 28  ? 223.863 205.843 236.805 1.00 107.40 ? 267 LYS E CE  1 
ATOM   5918 N NZ  . LYS D 2 28  ? 224.597 205.872 238.100 1.00 105.52 ? 267 LYS E NZ  1 
ATOM   5919 N N   . GLU D 2 29  ? 219.149 204.084 236.201 1.00 103.63 ? 268 GLU E N   1 
ATOM   5920 C CA  . GLU D 2 29  ? 218.166 204.049 237.278 1.00 100.22 ? 268 GLU E CA  1 
ATOM   5921 C C   . GLU D 2 29  ? 218.299 202.778 238.106 1.00 99.55  ? 268 GLU E C   1 
ATOM   5922 O O   . GLU D 2 29  ? 218.251 202.827 239.341 1.00 103.45 ? 268 GLU E O   1 
ATOM   5923 C CB  . GLU D 2 29  ? 216.755 204.179 236.708 1.00 99.84  ? 268 GLU E CB  1 
ATOM   5924 C CG  . GLU D 2 29  ? 216.435 205.565 236.172 1.00 103.97 ? 268 GLU E CG  1 
ATOM   5925 C CD  . GLU D 2 29  ? 217.288 206.647 236.808 1.00 106.85 ? 268 GLU E CD  1 
ATOM   5926 O OE1 . GLU D 2 29  ? 217.023 207.005 237.975 1.00 108.16 ? 268 GLU E OE1 1 
ATOM   5927 O OE2 . GLU D 2 29  ? 218.225 207.137 236.143 1.00 107.39 ? 268 GLU E OE2 1 
ATOM   5928 N N   . LEU D 2 30  ? 218.479 201.631 237.446 1.00 88.40  ? 269 LEU E N   1 
ATOM   5929 C CA  . LEU D 2 30  ? 218.623 200.379 238.185 1.00 90.01  ? 269 LEU E CA  1 
ATOM   5930 C C   . LEU D 2 30  ? 219.850 200.407 239.091 1.00 92.08  ? 269 LEU E C   1 
ATOM   5931 O O   . LEU D 2 30  ? 219.782 199.994 240.256 1.00 95.51  ? 269 LEU E O   1 
ATOM   5932 C CB  . LEU D 2 30  ? 218.695 199.201 237.214 1.00 91.87  ? 269 LEU E CB  1 
ATOM   5933 C CG  . LEU D 2 30  ? 217.396 198.429 236.961 1.00 91.80  ? 269 LEU E CG  1 
ATOM   5934 C CD1 . LEU D 2 30  ? 217.122 197.458 238.098 1.00 89.84  ? 269 LEU E CD1 1 
ATOM   5935 C CD2 . LEU D 2 30  ? 216.218 199.373 236.770 1.00 90.04  ? 269 LEU E CD2 1 
ATOM   5936 N N   . GLU D 2 31  ? 220.977 200.909 238.582 1.00 95.18  ? 270 GLU E N   1 
ATOM   5937 C CA  . GLU D 2 31  ? 222.177 200.985 239.413 1.00 97.31  ? 270 GLU E CA  1 
ATOM   5938 C C   . GLU D 2 31  ? 222.013 201.968 240.569 1.00 96.81  ? 270 GLU E C   1 
ATOM   5939 O O   . GLU D 2 31  ? 222.470 201.697 241.691 1.00 96.86  ? 270 GLU E O   1 
ATOM   5940 C CB  . GLU D 2 31  ? 223.385 201.358 238.556 1.00 96.73  ? 270 GLU E CB  1 
ATOM   5941 C CG  . GLU D 2 31  ? 223.620 200.416 237.386 1.00 98.15  ? 270 GLU E CG  1 
ATOM   5942 C CD  . GLU D 2 31  ? 223.281 198.974 237.719 1.00 99.53  ? 270 GLU E CD  1 
ATOM   5943 O OE1 . GLU D 2 31  ? 223.923 198.403 238.626 1.00 101.23 ? 270 GLU E OE1 1 
ATOM   5944 O OE2 . GLU D 2 31  ? 222.368 198.413 237.077 1.00 98.32  ? 270 GLU E OE2 1 
ATOM   5945 N N   . LYS D 2 32  ? 221.372 203.112 240.324 1.00 87.48  ? 271 LYS E N   1 
ATOM   5946 C CA  . LYS D 2 32  ? 221.191 204.086 241.392 1.00 85.46  ? 271 LYS E CA  1 
ATOM   5947 C C   . LYS D 2 32  ? 220.283 203.514 242.475 1.00 85.29  ? 271 LYS E C   1 
ATOM   5948 O O   . LYS D 2 32  ? 220.502 203.748 243.670 1.00 87.12  ? 271 LYS E O   1 
ATOM   5949 C CB  . LYS D 2 32  ? 220.663 205.400 240.792 1.00 87.80  ? 271 LYS E CB  1 
ATOM   5950 C CG  . LYS D 2 32  ? 220.356 206.598 241.723 1.00 88.08  ? 271 LYS E CG  1 
ATOM   5951 C CD  . LYS D 2 32  ? 219.216 206.436 242.713 1.00 91.34  ? 271 LYS E CD  1 
ATOM   5952 C CE  . LYS D 2 32  ? 217.912 206.112 242.012 1.00 91.33  ? 271 LYS E CE  1 
ATOM   5953 N NZ  . LYS D 2 32  ? 216.840 205.807 242.993 1.00 92.67  ? 271 LYS E NZ  1 
ATOM   5954 N N   . GLU D 2 33  ? 219.280 202.725 242.080 1.00 84.20  ? 272 GLU E N   1 
ATOM   5955 C CA  . GLU D 2 33  ? 218.450 202.062 243.080 1.00 85.26  ? 272 GLU E CA  1 
ATOM   5956 C C   . GLU D 2 33  ? 219.212 200.967 243.818 1.00 84.51  ? 272 GLU E C   1 
ATOM   5957 O O   . GLU D 2 33  ? 218.948 200.730 244.999 1.00 86.20  ? 272 GLU E O   1 
ATOM   5958 C CB  . GLU D 2 33  ? 217.182 201.504 242.441 1.00 82.93  ? 272 GLU E CB  1 
ATOM   5959 C CG  . GLU D 2 33  ? 216.365 202.564 241.738 1.00 86.41  ? 272 GLU E CG  1 
ATOM   5960 C CD  . GLU D 2 33  ? 215.346 203.207 242.651 1.00 88.70  ? 272 GLU E CD  1 
ATOM   5961 O OE1 . GLU D 2 33  ? 215.382 202.936 243.870 1.00 91.75  ? 272 GLU E OE1 1 
ATOM   5962 O OE2 . GLU D 2 33  ? 214.506 203.984 242.153 1.00 89.29  ? 272 GLU E OE2 1 
ATOM   5963 N N   . ARG D 2 34  ? 220.147 200.288 243.150 1.00 86.74  ? 273 ARG E N   1 
ATOM   5964 C CA  . ARG D 2 34  ? 221.063 199.406 243.873 1.00 85.45  ? 273 ARG E CA  1 
ATOM   5965 C C   . ARG D 2 34  ? 221.793 200.162 244.976 1.00 89.31  ? 273 ARG E C   1 
ATOM   5966 O O   . ARG D 2 34  ? 221.902 199.679 246.113 1.00 93.48  ? 273 ARG E O   1 
ATOM   5967 C CB  . ARG D 2 34  ? 222.068 198.779 242.904 1.00 87.43  ? 273 ARG E CB  1 
ATOM   5968 C CG  . ARG D 2 34  ? 221.485 197.803 241.890 1.00 89.36  ? 273 ARG E CG  1 
ATOM   5969 C CD  . ARG D 2 34  ? 221.251 196.416 242.486 1.00 91.26  ? 273 ARG E CD  1 
ATOM   5970 N NE  . ARG D 2 34  ? 220.326 196.409 243.611 1.00 94.18  ? 273 ARG E NE  1 
ATOM   5971 C CZ  . ARG D 2 34  ? 219.016 196.241 243.507 1.00 95.21  ? 273 ARG E CZ  1 
ATOM   5972 N NH1 . ARG D 2 34  ? 218.433 196.066 242.333 1.00 93.99  ? 273 ARG E NH1 1 
ATOM   5973 N NH2 . ARG D 2 34  ? 218.274 196.250 244.610 1.00 93.91  ? 273 ARG E NH2 1 
ATOM   5974 N N   . VAL D 2 35  ? 222.291 201.357 244.658 1.00 84.65  ? 274 VAL E N   1 
ATOM   5975 C CA  . VAL D 2 35  ? 222.979 202.169 245.662 1.00 83.94  ? 274 VAL E CA  1 
ATOM   5976 C C   . VAL D 2 35  ? 222.030 202.534 246.802 1.00 84.04  ? 274 VAL E C   1 
ATOM   5977 O O   . VAL D 2 35  ? 222.398 202.476 247.986 1.00 84.77  ? 274 VAL E O   1 
ATOM   5978 C CB  . VAL D 2 35  ? 223.590 203.420 245.005 1.00 88.57  ? 274 VAL E CB  1 
ATOM   5979 C CG1 . VAL D 2 35  ? 223.679 204.568 246.003 1.00 86.00  ? 274 VAL E CG1 1 
ATOM   5980 C CG2 . VAL D 2 35  ? 224.960 203.099 244.428 1.00 88.68  ? 274 VAL E CG2 1 
ATOM   5981 N N   . GLN D 2 36  ? 220.797 202.920 246.463 1.00 78.89  ? 275 GLN E N   1 
ATOM   5982 C CA  . GLN D 2 36  ? 219.822 203.282 247.491 1.00 74.03  ? 275 GLN E CA  1 
ATOM   5983 C C   . GLN D 2 36  ? 219.518 202.110 248.415 1.00 73.38  ? 275 GLN E C   1 
ATOM   5984 O O   . GLN D 2 36  ? 219.416 202.283 249.636 1.00 76.69  ? 275 GLN E O   1 
ATOM   5985 C CB  . GLN D 2 36  ? 218.533 203.793 246.850 1.00 72.46  ? 275 GLN E CB  1 
ATOM   5986 C CG  . GLN D 2 36  ? 218.718 204.976 245.930 1.00 78.48  ? 275 GLN E CG  1 
ATOM   5987 C CD  . GLN D 2 36  ? 218.686 206.294 246.673 1.00 82.29  ? 275 GLN E CD  1 
ATOM   5988 O OE1 . GLN D 2 36  ? 218.704 206.326 247.903 1.00 83.56  ? 275 GLN E OE1 1 
ATOM   5989 N NE2 . GLN D 2 36  ? 218.638 207.392 245.929 1.00 82.50  ? 275 GLN E NE2 1 
ATOM   5990 N N   . LYS D 2 37  ? 219.348 200.911 247.854 1.00 72.42  ? 276 LYS E N   1 
ATOM   5991 C CA  . LYS D 2 37  ? 219.078 199.753 248.698 1.00 72.77  ? 276 LYS E CA  1 
ATOM   5992 C C   . LYS D 2 37  ? 220.280 199.389 249.556 1.00 72.63  ? 276 LYS E C   1 
ATOM   5993 O O   . LYS D 2 37  ? 220.106 198.952 250.697 1.00 78.77  ? 276 LYS E O   1 
ATOM   5994 C CB  . LYS D 2 37  ? 218.628 198.549 247.863 1.00 76.92  ? 276 LYS E CB  1 
ATOM   5995 C CG  . LYS D 2 37  ? 217.529 198.818 246.828 1.00 79.40  ? 276 LYS E CG  1 
ATOM   5996 C CD  . LYS D 2 37  ? 216.439 199.783 247.306 1.00 73.72  ? 276 LYS E CD  1 
ATOM   5997 C CE  . LYS D 2 37  ? 215.703 199.267 248.534 1.00 71.91  ? 276 LYS E CE  1 
ATOM   5998 N NZ  . LYS D 2 37  ? 215.310 197.847 248.366 1.00 74.52  ? 276 LYS E NZ  1 
ATOM   5999 N N   . GLU D 2 38  ? 221.499 199.571 249.046 1.00 76.20  ? 277 GLU E N   1 
ATOM   6000 C CA  . GLU D 2 38  ? 222.664 199.367 249.903 1.00 78.70  ? 277 GLU E CA  1 
ATOM   6001 C C   . GLU D 2 38  ? 222.654 200.333 251.084 1.00 79.64  ? 277 GLU E C   1 
ATOM   6002 O O   . GLU D 2 38  ? 222.906 199.931 252.231 1.00 80.87  ? 277 GLU E O   1 
ATOM   6003 C CB  . GLU D 2 38  ? 223.949 199.525 249.092 1.00 78.94  ? 277 GLU E CB  1 
ATOM   6004 C CG  . GLU D 2 38  ? 225.210 199.172 249.863 1.00 81.30  ? 277 GLU E CG  1 
ATOM   6005 C CD  . GLU D 2 38  ? 225.852 200.379 250.515 1.00 84.02  ? 277 GLU E CD  1 
ATOM   6006 O OE1 . GLU D 2 38  ? 225.358 201.506 250.302 1.00 84.84  ? 277 GLU E OE1 1 
ATOM   6007 O OE2 . GLU D 2 38  ? 226.850 200.201 251.244 1.00 84.12  ? 277 GLU E OE2 1 
ATOM   6008 N N   . GLU D 2 39  ? 222.354 201.607 250.826 1.00 78.24  ? 278 GLU E N   1 
ATOM   6009 C CA  . GLU D 2 39  ? 222.322 202.588 251.909 1.00 75.62  ? 278 GLU E CA  1 
ATOM   6010 C C   . GLU D 2 39  ? 221.236 202.261 252.930 1.00 72.97  ? 278 GLU E C   1 
ATOM   6011 O O   . GLU D 2 39  ? 221.469 202.343 254.145 1.00 70.65  ? 278 GLU E O   1 
ATOM   6012 C CB  . GLU D 2 39  ? 222.118 203.990 251.340 1.00 82.47  ? 278 GLU E CB  1 
ATOM   6013 C CG  . GLU D 2 39  ? 222.244 205.094 252.372 1.00 84.58  ? 278 GLU E CG  1 
ATOM   6014 C CD  . GLU D 2 39  ? 223.553 205.027 253.131 1.00 87.64  ? 278 GLU E CD  1 
ATOM   6015 O OE1 . GLU D 2 39  ? 224.612 204.905 252.482 1.00 89.59  ? 278 GLU E OE1 1 
ATOM   6016 O OE2 . GLU D 2 39  ? 223.522 205.095 254.378 1.00 88.08  ? 278 GLU E OE2 1 
ATOM   6017 N N   . GLU D 2 40  ? 220.045 201.886 252.460 1.00 70.84  ? 279 GLU E N   1 
ATOM   6018 C CA  . GLU D 2 40  ? 218.972 201.549 253.387 1.00 65.21  ? 279 GLU E CA  1 
ATOM   6019 C C   . GLU D 2 40  ? 219.264 200.266 254.155 1.00 66.34  ? 279 GLU E C   1 
ATOM   6020 O O   . GLU D 2 40  ? 218.861 200.153 255.314 1.00 68.77  ? 279 GLU E O   1 
ATOM   6021 C CB  . GLU D 2 40  ? 217.635 201.445 252.648 1.00 66.00  ? 279 GLU E CB  1 
ATOM   6022 C CG  . GLU D 2 40  ? 217.400 200.139 251.916 1.00 73.53  ? 279 GLU E CG  1 
ATOM   6023 C CD  . GLU D 2 40  ? 216.584 199.157 252.728 1.00 73.76  ? 279 GLU E CD  1 
ATOM   6024 O OE1 . GLU D 2 40  ? 215.998 199.572 253.749 1.00 74.41  ? 279 GLU E OE1 1 
ATOM   6025 O OE2 . GLU D 2 40  ? 216.529 197.970 252.345 1.00 72.98  ? 279 GLU E OE2 1 
ATOM   6026 N N   . LEU D 2 41  ? 219.971 199.311 253.546 1.00 65.96  ? 280 LEU E N   1 
ATOM   6027 C CA  . LEU D 2 41  ? 220.412 198.133 254.283 1.00 63.43  ? 280 LEU E CA  1 
ATOM   6028 C C   . LEU D 2 41  ? 221.386 198.515 255.387 1.00 65.93  ? 280 LEU E C   1 
ATOM   6029 O O   . LEU D 2 41  ? 221.324 197.973 256.496 1.00 70.93  ? 280 LEU E O   1 
ATOM   6030 C CB  . LEU D 2 41  ? 221.052 197.128 253.327 1.00 63.37  ? 280 LEU E CB  1 
ATOM   6031 C CG  . LEU D 2 41  ? 220.815 195.646 253.622 1.00 71.43  ? 280 LEU E CG  1 
ATOM   6032 C CD1 . LEU D 2 41  ? 219.453 195.427 254.264 1.00 70.93  ? 280 LEU E CD1 1 
ATOM   6033 C CD2 . LEU D 2 41  ? 220.950 194.823 252.352 1.00 71.90  ? 280 LEU E CD2 1 
ATOM   6034 N N   . GLN D 2 42  ? 222.298 199.445 255.101 1.00 69.19  ? 281 GLN E N   1 
ATOM   6035 C CA  . GLN D 2 42  ? 223.226 199.897 256.134 1.00 69.98  ? 281 GLN E CA  1 
ATOM   6036 C C   . GLN D 2 42  ? 222.471 200.552 257.285 1.00 68.65  ? 281 GLN E C   1 
ATOM   6037 O O   . GLN D 2 42  ? 222.746 200.268 258.460 1.00 67.85  ? 281 GLN E O   1 
ATOM   6038 C CB  . GLN D 2 42  ? 224.265 200.836 255.501 1.00 72.08  ? 281 GLN E CB  1 
ATOM   6039 C CG  . GLN D 2 42  ? 225.542 201.206 256.303 1.00 71.49  ? 281 GLN E CG  1 
ATOM   6040 C CD  . GLN D 2 42  ? 225.341 201.856 257.669 1.00 74.84  ? 281 GLN E CD  1 
ATOM   6041 O OE1 . GLN D 2 42  ? 224.294 202.420 257.970 1.00 75.12  ? 281 GLN E OE1 1 
ATOM   6042 N NE2 . GLN D 2 42  ? 226.368 201.772 258.505 1.00 76.31  ? 281 GLN E NE2 1 
ATOM   6043 N N   . VAL D 2 43  ? 221.501 201.413 256.969 1.00 61.80  ? 282 VAL E N   1 
ATOM   6044 C CA  . VAL D 2 43  ? 220.739 202.081 258.024 1.00 55.80  ? 282 VAL E CA  1 
ATOM   6045 C C   . VAL D 2 43  ? 219.932 201.065 258.827 1.00 56.85  ? 282 VAL E C   1 
ATOM   6046 O O   . VAL D 2 43  ? 219.828 201.162 260.056 1.00 59.20  ? 282 VAL E O   1 
ATOM   6047 C CB  . VAL D 2 43  ? 219.840 203.182 257.430 1.00 56.76  ? 282 VAL E CB  1 
ATOM   6048 C CG1 . VAL D 2 43  ? 219.128 203.937 258.538 1.00 55.05  ? 282 VAL E CG1 1 
ATOM   6049 C CG2 . VAL D 2 43  ? 220.661 204.141 256.593 1.00 62.34  ? 282 VAL E CG2 1 
ATOM   6050 N N   . LYS D 2 44  ? 219.348 200.077 258.146 1.00 60.47  ? 283 LYS E N   1 
ATOM   6051 C CA  . LYS D 2 44  ? 218.577 199.044 258.829 1.00 57.05  ? 283 LYS E CA  1 
ATOM   6052 C C   . LYS D 2 44  ? 219.459 198.225 259.761 1.00 55.05  ? 283 LYS E C   1 
ATOM   6053 O O   . LYS D 2 44  ? 219.055 197.884 260.877 1.00 56.95  ? 283 LYS E O   1 
ATOM   6054 C CB  . LYS D 2 44  ? 217.896 198.145 257.796 1.00 60.26  ? 283 LYS E CB  1 
ATOM   6055 C CG  . LYS D 2 44  ? 217.169 196.950 258.379 1.00 62.43  ? 283 LYS E CG  1 
ATOM   6056 C CD  . LYS D 2 44  ? 215.665 197.157 258.354 1.00 63.87  ? 283 LYS E CD  1 
ATOM   6057 C CE  . LYS D 2 44  ? 214.929 195.874 258.695 1.00 60.60  ? 283 LYS E CE  1 
ATOM   6058 N NZ  . LYS D 2 44  ? 213.684 196.147 259.456 1.00 54.92  ? 283 LYS E NZ  1 
ATOM   6059 N N   . GLU D 2 45  ? 220.671 197.893 259.314 1.00 64.19  ? 284 GLU E N   1 
ATOM   6060 C CA  . GLU D 2 45  ? 221.591 197.145 260.162 1.00 65.38  ? 284 GLU E CA  1 
ATOM   6061 C C   . GLU D 2 45  ? 222.005 197.959 261.381 1.00 69.36  ? 284 GLU E C   1 
ATOM   6062 O O   . GLU D 2 45  ? 222.111 197.417 262.487 1.00 70.77  ? 284 GLU E O   1 
ATOM   6063 C CB  . GLU D 2 45  ? 222.816 196.717 259.357 1.00 70.65  ? 284 GLU E CB  1 
ATOM   6064 C CG  . GLU D 2 45  ? 222.595 195.465 258.529 1.00 71.00  ? 284 GLU E CG  1 
ATOM   6065 C CD  . GLU D 2 45  ? 221.902 194.369 259.310 1.00 74.64  ? 284 GLU E CD  1 
ATOM   6066 O OE1 . GLU D 2 45  ? 222.378 194.029 260.414 1.00 71.98  ? 284 GLU E OE1 1 
ATOM   6067 O OE2 . GLU D 2 45  ? 220.878 193.847 258.822 1.00 77.39  ? 284 GLU E OE2 1 
ATOM   6068 N N   . LYS D 2 46  ? 222.251 199.258 261.200 1.00 60.09  ? 285 LYS E N   1 
ATOM   6069 C CA  . LYS D 2 46  ? 222.564 200.102 262.350 1.00 56.97  ? 285 LYS E CA  1 
ATOM   6070 C C   . LYS D 2 46  ? 221.400 200.163 263.331 1.00 57.10  ? 285 LYS E C   1 
ATOM   6071 O O   . LYS D 2 46  ? 221.606 200.104 264.551 1.00 53.35  ? 285 LYS E O   1 
ATOM   6072 C CB  . LYS D 2 46  ? 222.943 201.508 261.888 1.00 60.92  ? 285 LYS E CB  1 
ATOM   6073 C CG  . LYS D 2 46  ? 223.413 202.425 263.007 1.00 64.95  ? 285 LYS E CG  1 
ATOM   6074 C CD  . LYS D 2 46  ? 224.596 201.842 263.769 1.00 64.03  ? 285 LYS E CD  1 
ATOM   6075 C CE  . LYS D 2 46  ? 225.747 201.484 262.838 1.00 65.31  ? 285 LYS E CE  1 
ATOM   6076 N NZ  . LYS D 2 46  ? 226.285 202.683 262.140 1.00 66.30  ? 285 LYS E NZ  1 
ATOM   6077 N N   . LEU D 2 47  ? 220.174 200.271 262.817 1.00 57.15  ? 286 LEU E N   1 
ATOM   6078 C CA  . LEU D 2 47  ? 218.998 200.261 263.679 1.00 54.00  ? 286 LEU E CA  1 
ATOM   6079 C C   . LEU D 2 47  ? 218.881 198.948 264.443 1.00 55.40  ? 286 LEU E C   1 
ATOM   6080 O O   . LEU D 2 47  ? 218.558 198.937 265.636 1.00 58.14  ? 286 LEU E O   1 
ATOM   6081 C CB  . LEU D 2 47  ? 217.745 200.501 262.845 1.00 53.92  ? 286 LEU E CB  1 
ATOM   6082 C CG  . LEU D 2 47  ? 216.624 201.255 263.543 1.00 53.75  ? 286 LEU E CG  1 
ATOM   6083 C CD1 . LEU D 2 47  ? 217.096 202.639 263.937 1.00 55.65  ? 286 LEU E CD1 1 
ATOM   6084 C CD2 . LEU D 2 47  ? 215.426 201.319 262.626 1.00 55.44  ? 286 LEU E CD2 1 
ATOM   6085 N N   . GLN D 2 48  ? 219.121 197.827 263.763 1.00 56.21  ? 287 GLN E N   1 
ATOM   6086 C CA  . GLN D 2 48  ? 219.039 196.530 264.425 1.00 53.64  ? 287 GLN E CA  1 
ATOM   6087 C C   . GLN D 2 48  ? 220.109 196.391 265.497 1.00 53.82  ? 287 GLN E C   1 
ATOM   6088 O O   . GLN D 2 48  ? 219.848 195.840 266.571 1.00 57.34  ? 287 GLN E O   1 
ATOM   6089 C CB  . GLN D 2 48  ? 219.155 195.400 263.401 1.00 62.87  ? 287 GLN E CB  1 
ATOM   6090 C CG  . GLN D 2 48  ? 218.583 194.065 263.874 1.00 63.57  ? 287 GLN E CG  1 
ATOM   6091 C CD  . GLN D 2 48  ? 219.451 193.378 264.916 1.00 60.01  ? 287 GLN E CD  1 
ATOM   6092 O OE1 . GLN D 2 48  ? 220.678 193.423 264.846 1.00 61.64  ? 287 GLN E OE1 1 
ATOM   6093 N NE2 . GLN D 2 48  ? 218.813 192.748 265.893 1.00 53.69  ? 287 GLN E NE2 1 
ATOM   6094 N N   . GLU D 2 49  ? 221.322 196.875 265.226 1.00 51.64  ? 288 GLU E N   1 
ATOM   6095 C CA  . GLU D 2 49  ? 222.366 196.832 266.243 1.00 57.91  ? 288 GLU E CA  1 
ATOM   6096 C C   . GLU D 2 49  ? 221.982 197.672 267.451 1.00 55.62  ? 288 GLU E C   1 
ATOM   6097 O O   . GLU D 2 49  ? 222.177 197.256 268.601 1.00 55.05  ? 288 GLU E O   1 
ATOM   6098 C CB  . GLU D 2 49  ? 223.694 197.312 265.656 1.00 59.73  ? 288 GLU E CB  1 
ATOM   6099 C CG  . GLU D 2 49  ? 224.847 197.337 266.653 1.00 62.63  ? 288 GLU E CG  1 
ATOM   6100 C CD  . GLU D 2 49  ? 224.969 198.664 267.379 1.00 64.20  ? 288 GLU E CD  1 
ATOM   6101 O OE1 . GLU D 2 49  ? 225.035 199.710 266.701 1.00 67.19  ? 288 GLU E OE1 1 
ATOM   6102 O OE2 . GLU D 2 49  ? 224.993 198.660 268.627 1.00 58.87  ? 288 GLU E OE2 1 
ATOM   6103 N N   . GLU D 2 50  ? 221.429 198.859 267.209 1.00 51.89  ? 289 GLU E N   1 
ATOM   6104 C CA  . GLU D 2 50  ? 221.040 199.725 268.312 1.00 49.80  ? 289 GLU E CA  1 
ATOM   6105 C C   . GLU D 2 50  ? 219.892 199.129 269.119 1.00 46.13  ? 289 GLU E C   1 
ATOM   6106 O O   . GLU D 2 50  ? 219.852 199.289 270.343 1.00 53.14  ? 289 GLU E O   1 
ATOM   6107 C CB  . GLU D 2 50  ? 220.675 201.106 267.773 1.00 61.93  ? 289 GLU E CB  1 
ATOM   6108 C CG  . GLU D 2 50  ? 220.410 202.143 268.836 1.00 65.05  ? 289 GLU E CG  1 
ATOM   6109 C CD  . GLU D 2 50  ? 218.938 202.339 269.063 1.00 61.48  ? 289 GLU E CD  1 
ATOM   6110 O OE1 . GLU D 2 50  ? 218.161 201.506 268.556 1.00 53.98  ? 289 GLU E OE1 1 
ATOM   6111 O OE2 . GLU D 2 50  ? 218.559 203.322 269.733 1.00 63.70  ? 289 GLU E OE2 1 
ATOM   6112 N N   . LEU D 2 51  ? 218.955 198.442 268.461 1.00 41.77  ? 290 LEU E N   1 
ATOM   6113 C CA  . LEU D 2 51  ? 217.869 197.784 269.183 1.00 44.17  ? 290 LEU E CA  1 
ATOM   6114 C C   . LEU D 2 51  ? 218.313 196.477 269.829 1.00 42.81  ? 290 LEU E C   1 
ATOM   6115 O O   . LEU D 2 51  ? 217.604 195.956 270.695 1.00 39.50  ? 290 LEU E O   1 
ATOM   6116 C CB  . LEU D 2 51  ? 216.683 197.534 268.249 1.00 45.41  ? 290 LEU E CB  1 
ATOM   6117 C CG  . LEU D 2 51  ? 215.422 198.356 268.535 1.00 40.12  ? 290 LEU E CG  1 
ATOM   6118 C CD1 . LEU D 2 51  ? 214.390 198.186 267.437 1.00 40.34  ? 290 LEU E CD1 1 
ATOM   6119 C CD2 . LEU D 2 51  ? 214.824 197.982 269.876 1.00 43.74  ? 290 LEU E CD2 1 
ATOM   6120 N N   . ARG D 2 52  ? 219.450 195.923 269.408 1.00 51.79  ? 291 ARG E N   1 
ATOM   6121 C CA  . ARG D 2 52  ? 220.051 194.820 270.148 1.00 50.57  ? 291 ARG E CA  1 
ATOM   6122 C C   . ARG D 2 52  ? 220.720 195.335 271.417 1.00 51.16  ? 291 ARG E C   1 
ATOM   6123 O O   . ARG D 2 52  ? 220.612 194.717 272.482 1.00 55.57  ? 291 ARG E O   1 
ATOM   6124 C CB  . ARG D 2 52  ? 221.050 194.082 269.253 1.00 55.79  ? 291 ARG E CB  1 
ATOM   6125 C CG  . ARG D 2 52  ? 222.174 193.339 269.968 1.00 54.48  ? 291 ARG E CG  1 
ATOM   6126 C CD  . ARG D 2 52  ? 221.639 192.243 270.887 1.00 55.19  ? 291 ARG E CD  1 
ATOM   6127 N NE  . ARG D 2 52  ? 220.689 191.355 270.224 1.00 60.00  ? 291 ARG E NE  1 
ATOM   6128 C CZ  . ARG D 2 52  ? 220.959 190.598 269.168 1.00 64.82  ? 291 ARG E CZ  1 
ATOM   6129 N NH1 . ARG D 2 52  ? 222.172 190.545 268.642 1.00 63.82  ? 291 ARG E NH1 1 
ATOM   6130 N NH2 . ARG D 2 52  ? 219.989 189.861 268.635 1.00 65.74  ? 291 ARG E NH2 1 
ATOM   6131 N N   . TRP D 2 53  ? 221.396 196.482 271.325 1.00 56.68  ? 292 TRP E N   1 
ATOM   6132 C CA  . TRP D 2 53  ? 221.895 197.177 272.507 1.00 54.89  ? 292 TRP E CA  1 
ATOM   6133 C C   . TRP D 2 53  ? 220.757 197.686 273.385 1.00 54.72  ? 292 TRP E C   1 
ATOM   6134 O O   . TRP D 2 53  ? 220.991 198.053 274.541 1.00 54.98  ? 292 TRP E O   1 
ATOM   6135 C CB  . TRP D 2 53  ? 222.813 198.322 272.067 1.00 64.77  ? 292 TRP E CB  1 
ATOM   6136 C CG  . TRP D 2 53  ? 223.173 199.302 273.132 1.00 63.86  ? 292 TRP E CG  1 
ATOM   6137 C CD1 . TRP D 2 53  ? 224.085 199.129 274.128 1.00 58.77  ? 292 TRP E CD1 1 
ATOM   6138 C CD2 . TRP D 2 53  ? 222.643 200.622 273.296 1.00 60.99  ? 292 TRP E CD2 1 
ATOM   6139 N NE1 . TRP D 2 53  ? 224.150 200.256 274.910 1.00 61.92  ? 292 TRP E NE1 1 
ATOM   6140 C CE2 . TRP D 2 53  ? 223.274 201.188 274.419 1.00 61.23  ? 292 TRP E CE2 1 
ATOM   6141 C CE3 . TRP D 2 53  ? 221.692 201.378 272.606 1.00 53.33  ? 292 TRP E CE3 1 
ATOM   6142 C CZ2 . TRP D 2 53  ? 222.985 202.473 274.866 1.00 61.02  ? 292 TRP E CZ2 1 
ATOM   6143 C CZ3 . TRP D 2 53  ? 221.406 202.651 273.052 1.00 50.76  ? 292 TRP E CZ3 1 
ATOM   6144 C CH2 . TRP D 2 53  ? 222.050 203.186 274.171 1.00 55.69  ? 292 TRP E CH2 1 
ATOM   6145 N N   . ARG D 2 54  ? 219.533 197.671 272.865 1.00 50.78  ? 293 ARG E N   1 
ATOM   6146 C CA  . ARG D 2 54  ? 218.300 197.933 273.594 1.00 41.11  ? 293 ARG E CA  1 
ATOM   6147 C C   . ARG D 2 54  ? 217.938 196.696 274.403 1.00 45.49  ? 293 ARG E C   1 
ATOM   6148 O O   . ARG D 2 54  ? 218.827 195.942 274.810 1.00 48.08  ? 293 ARG E O   1 
ATOM   6149 C CB  . ARG D 2 54  ? 217.161 198.340 272.662 1.00 49.16  ? 293 ARG E CB  1 
ATOM   6150 C CG  . ARG D 2 54  ? 217.272 199.765 272.149 1.00 54.95  ? 293 ARG E CG  1 
ATOM   6151 C CD  . ARG D 2 54  ? 217.135 200.781 273.271 1.00 48.48  ? 293 ARG E CD  1 
ATOM   6152 N NE  . ARG D 2 54  ? 217.901 201.991 272.995 1.00 50.72  ? 293 ARG E NE  1 
ATOM   6153 C CZ  . ARG D 2 54  ? 217.608 203.192 273.475 1.00 47.14  ? 293 ARG E CZ  1 
ATOM   6154 N NH1 . ARG D 2 54  ? 216.564 203.385 274.261 1.00 50.51  ? 293 ARG E NH1 1 
ATOM   6155 N NH2 . ARG D 2 54  ? 218.381 204.224 273.154 1.00 39.85  ? 293 ARG E NH2 1 
ATOM   6156 N N   . ARG D 2 55  ? 216.649 196.464 274.636 1.00 61.67  ? 294 ARG E N   1 
ATOM   6157 C CA  . ARG D 2 55  ? 216.128 196.005 275.915 1.00 66.98  ? 294 ARG E CA  1 
ATOM   6158 C C   . ARG D 2 55  ? 216.712 194.679 276.394 1.00 57.49  ? 294 ARG E C   1 
ATOM   6159 O O   . ARG D 2 55  ? 216.009 193.679 276.570 1.00 47.84  ? 294 ARG E O   1 
ATOM   6160 C CB  . ARG D 2 55  ? 214.595 195.897 275.816 1.00 63.60  ? 294 ARG E CB  1 
ATOM   6161 C CG  . ARG D 2 55  ? 214.032 194.885 274.779 1.00 64.98  ? 294 ARG E CG  1 
ATOM   6162 C CD  . ARG D 2 55  ? 214.219 195.301 273.317 1.00 67.26  ? 294 ARG E CD  1 
ATOM   6163 N NE  . ARG D 2 55  ? 213.327 194.589 272.407 1.00 72.44  ? 294 ARG E NE  1 
ATOM   6164 C CZ  . ARG D 2 55  ? 213.679 194.135 271.211 1.00 62.83  ? 294 ARG E CZ  1 
ATOM   6165 N NH1 . ARG D 2 55  ? 214.911 194.278 270.751 1.00 54.50  ? 294 ARG E NH1 1 
ATOM   6166 N NH2 . ARG D 2 55  ? 212.771 193.521 270.458 1.00 57.83  ? 294 ARG E NH2 1 
ATOM   6167 N N   . THR D 2 56  ? 218.018 194.702 276.649 1.00 57.93  ? 295 THR E N   1 
ATOM   6168 C CA  . THR D 2 56  ? 218.651 193.887 277.672 1.00 56.52  ? 295 THR E CA  1 
ATOM   6169 C C   . THR D 2 56  ? 218.923 194.701 278.929 1.00 52.22  ? 295 THR E C   1 
ATOM   6170 O O   . THR D 2 56  ? 219.576 194.204 279.851 1.00 47.84  ? 295 THR E O   1 
ATOM   6171 C CB  . THR D 2 56  ? 219.961 193.287 277.152 1.00 55.95  ? 295 THR E CB  1 
ATOM   6172 O OG1 . THR D 2 56  ? 220.592 192.539 278.198 1.00 56.67  ? 295 THR E OG1 1 
ATOM   6173 C CG2 . THR D 2 56  ? 220.905 194.383 276.700 1.00 51.18  ? 295 THR E CG2 1 
ATOM   6174 N N   . PHE D 2 57  ? 218.433 195.936 278.976 1.00 45.29  ? 296 PHE E N   1 
ATOM   6175 C CA  . PHE D 2 57  ? 218.732 196.890 280.032 1.00 41.19  ? 296 PHE E CA  1 
ATOM   6176 C C   . PHE D 2 57  ? 217.560 196.997 280.995 1.00 44.30  ? 296 PHE E C   1 
ATOM   6177 O O   . PHE D 2 57  ? 216.398 196.976 280.581 1.00 47.76  ? 296 PHE E O   1 
ATOM   6178 C CB  . PHE D 2 57  ? 219.029 198.270 279.444 1.00 44.77  ? 296 PHE E CB  1 
ATOM   6179 C CG  . PHE D 2 57  ? 220.458 198.465 279.042 1.00 47.38  ? 296 PHE E CG  1 
ATOM   6180 C CD1 . PHE D 2 57  ? 221.479 197.839 279.733 1.00 50.98  ? 296 PHE E CD1 1 
ATOM   6181 C CD2 . PHE D 2 57  ? 220.781 199.278 277.972 1.00 45.35  ? 296 PHE E CD2 1 
ATOM   6182 C CE1 . PHE D 2 57  ? 222.795 198.018 279.363 1.00 50.50  ? 296 PHE E CE1 1 
ATOM   6183 C CE2 . PHE D 2 57  ? 222.094 199.460 277.597 1.00 49.28  ? 296 PHE E CE2 1 
ATOM   6184 C CZ  . PHE D 2 57  ? 223.101 198.829 278.293 1.00 51.57  ? 296 PHE E CZ  1 
ATOM   6185 N N   . LEU D 2 58  ? 217.872 197.117 282.281 1.00 44.07  ? 297 LEU E N   1 
ATOM   6186 C CA  . LEU D 2 58  ? 216.837 197.321 283.282 1.00 37.58  ? 297 LEU E CA  1 
ATOM   6187 C C   . LEU D 2 58  ? 216.230 198.708 283.118 1.00 42.50  ? 297 LEU E C   1 
ATOM   6188 O O   . LEU D 2 58  ? 216.949 199.707 283.028 1.00 47.44  ? 297 LEU E O   1 
ATOM   6189 C CB  . LEU D 2 58  ? 217.422 197.146 284.681 1.00 34.85  ? 297 LEU E CB  1 
ATOM   6190 C CG  . LEU D 2 58  ? 216.506 197.439 285.866 1.00 39.42  ? 297 LEU E CG  1 
ATOM   6191 C CD1 . LEU D 2 58  ? 215.191 196.700 285.727 1.00 39.84  ? 297 LEU E CD1 1 
ATOM   6192 C CD2 . LEU D 2 58  ? 217.201 197.061 287.160 1.00 46.53  ? 297 LEU E CD2 1 
ATOM   6193 N N   . HIS D 2 59  ? 214.904 198.769 283.079 1.00 40.66  ? 298 HIS E N   1 
ATOM   6194 C CA  . HIS D 2 59  ? 214.181 199.991 282.757 1.00 40.03  ? 298 HIS E CA  1 
ATOM   6195 C C   . HIS D 2 59  ? 213.500 200.523 284.012 1.00 50.19  ? 298 HIS E C   1 
ATOM   6196 O O   . HIS D 2 59  ? 212.606 199.871 284.561 1.00 60.52  ? 298 HIS E O   1 
ATOM   6197 C CB  . HIS D 2 59  ? 213.162 199.724 281.649 1.00 41.98  ? 298 HIS E CB  1 
ATOM   6198 C CG  . HIS D 2 59  ? 211.979 200.639 281.673 1.00 46.29  ? 298 HIS E CG  1 
ATOM   6199 N ND1 . HIS D 2 59  ? 212.096 202.010 281.727 1.00 50.99  ? 298 HIS E ND1 1 
ATOM   6200 C CD2 . HIS D 2 59  ? 210.651 200.375 281.650 1.00 45.22  ? 298 HIS E CD2 1 
ATOM   6201 C CE1 . HIS D 2 59  ? 210.892 202.553 281.735 1.00 53.51  ? 298 HIS E CE1 1 
ATOM   6202 N NE2 . HIS D 2 59  ? 209.998 201.582 281.690 1.00 52.09  ? 298 HIS E NE2 1 
ATOM   6203 N N   . ALA D 2 60  ? 213.925 201.703 284.461 1.00 44.93  ? 299 ALA E N   1 
ATOM   6204 C CA  . ALA D 2 60  ? 213.353 202.343 285.645 1.00 43.73  ? 299 ALA E CA  1 
ATOM   6205 C C   . ALA D 2 60  ? 212.096 203.082 285.210 1.00 43.95  ? 299 ALA E C   1 
ATOM   6206 O O   . ALA D 2 60  ? 212.152 204.170 284.637 1.00 43.70  ? 299 ALA E O   1 
ATOM   6207 C CB  . ALA D 2 60  ? 214.363 203.275 286.300 1.00 43.60  ? 299 ALA E CB  1 
ATOM   6208 N N   . VAL D 2 61  ? 210.941 202.480 285.490 1.00 46.82  ? 300 VAL E N   1 
ATOM   6209 C CA  . VAL D 2 61  ? 209.681 203.009 284.988 1.00 54.66  ? 300 VAL E CA  1 
ATOM   6210 C C   . VAL D 2 61  ? 209.230 204.193 285.833 1.00 52.20  ? 300 VAL E C   1 
ATOM   6211 O O   . VAL D 2 61  ? 209.342 204.187 287.066 1.00 52.51  ? 300 VAL E O   1 
ATOM   6212 C CB  . VAL D 2 61  ? 208.618 201.896 284.943 1.00 46.48  ? 300 VAL E CB  1 
ATOM   6213 C CG1 . VAL D 2 61  ? 208.353 201.343 286.326 1.00 40.24  ? 300 VAL E CG1 1 
ATOM   6214 C CG2 . VAL D 2 61  ? 207.331 202.410 284.319 1.00 50.28  ? 300 VAL E CG2 1 
ATOM   6215 N N   . ASP D 2 62  ? 208.743 205.234 285.162 1.00 46.95  ? 301 ASP E N   1 
ATOM   6216 C CA  . ASP D 2 62  ? 208.142 206.392 285.821 1.00 46.98  ? 301 ASP E CA  1 
ATOM   6217 C C   . ASP D 2 62  ? 206.653 206.110 285.961 1.00 49.49  ? 301 ASP E C   1 
ATOM   6218 O O   . ASP D 2 62  ? 205.859 206.379 285.059 1.00 56.34  ? 301 ASP E O   1 
ATOM   6219 C CB  . ASP D 2 62  ? 208.412 207.661 285.024 1.00 54.70  ? 301 ASP E CB  1 
ATOM   6220 C CG  . ASP D 2 62  ? 207.953 208.911 285.742 1.00 64.29  ? 301 ASP E CG  1 
ATOM   6221 O OD1 . ASP D 2 62  ? 208.730 209.450 286.558 1.00 64.92  ? 301 ASP E OD1 1 
ATOM   6222 O OD2 . ASP D 2 62  ? 206.816 209.357 285.485 1.00 69.22  ? 301 ASP E OD2 1 
ATOM   6223 N N   . VAL D 2 63  ? 206.269 205.564 287.109 1.00 43.71  ? 302 VAL E N   1 
ATOM   6224 C CA  . VAL D 2 63  ? 204.931 205.009 287.282 1.00 43.75  ? 302 VAL E CA  1 
ATOM   6225 C C   . VAL D 2 63  ? 203.918 206.136 287.421 1.00 44.30  ? 302 VAL E C   1 
ATOM   6226 O O   . VAL D 2 63  ? 204.073 207.031 288.260 1.00 49.15  ? 302 VAL E O   1 
ATOM   6227 C CB  . VAL D 2 63  ? 204.884 204.072 288.498 1.00 49.05  ? 302 VAL E CB  1 
ATOM   6228 C CG1 . VAL D 2 63  ? 203.453 203.675 288.804 1.00 50.22  ? 302 VAL E CG1 1 
ATOM   6229 C CG2 . VAL D 2 63  ? 205.730 202.844 288.250 1.00 46.96  ? 302 VAL E CG2 1 
ATOM   6230 N N   . VAL D 2 64  ? 202.876 206.092 286.596 1.00 36.08  ? 303 VAL E N   1 
ATOM   6231 C CA  . VAL D 2 64  ? 201.722 206.974 286.711 1.00 36.55  ? 303 VAL E CA  1 
ATOM   6232 C C   . VAL D 2 64  ? 200.494 206.097 286.899 1.00 36.71  ? 303 VAL E C   1 
ATOM   6233 O O   . VAL D 2 64  ? 200.329 205.096 286.194 1.00 40.25  ? 303 VAL E O   1 
ATOM   6234 C CB  . VAL D 2 64  ? 201.563 207.882 285.479 1.00 41.04  ? 303 VAL E CB  1 
ATOM   6235 C CG1 . VAL D 2 64  ? 200.575 208.996 285.768 1.00 41.75  ? 303 VAL E CG1 1 
ATOM   6236 C CG2 . VAL D 2 64  ? 202.906 208.455 285.066 1.00 46.88  ? 303 VAL E CG2 1 
ATOM   6237 N N   . LEU D 2 65  ? 199.648 206.460 287.853 1.00 47.72  ? 304 LEU E N   1 
ATOM   6238 C CA  . LEU D 2 65  ? 198.516 205.623 288.210 1.00 49.21  ? 304 LEU E CA  1 
ATOM   6239 C C   . LEU D 2 65  ? 197.290 205.984 287.374 1.00 48.00  ? 304 LEU E C   1 
ATOM   6240 O O   . LEU D 2 65  ? 197.220 207.039 286.742 1.00 55.75  ? 304 LEU E O   1 
ATOM   6241 C CB  . LEU D 2 65  ? 198.220 205.744 289.705 1.00 50.74  ? 304 LEU E CB  1 
ATOM   6242 C CG  . LEU D 2 65  ? 199.305 205.153 290.612 1.00 46.88  ? 304 LEU E CG  1 
ATOM   6243 C CD1 . LEU D 2 65  ? 198.754 204.761 291.961 1.00 40.44  ? 304 LEU E CD1 1 
ATOM   6244 C CD2 . LEU D 2 65  ? 199.968 203.952 289.959 1.00 55.37  ? 304 LEU E CD2 1 
ATOM   6245 N N   . ASP D 2 66  ? 196.315 205.081 287.376 1.00 57.89  ? 305 ASP E N   1 
ATOM   6246 C CA  . ASP D 2 66  ? 195.132 205.217 286.536 1.00 61.30  ? 305 ASP E CA  1 
ATOM   6247 C C   . ASP D 2 66  ? 193.928 205.590 287.386 1.00 65.45  ? 305 ASP E C   1 
ATOM   6248 O O   . ASP D 2 66  ? 193.447 204.756 288.169 1.00 72.42  ? 305 ASP E O   1 
ATOM   6249 C CB  . ASP D 2 66  ? 194.870 203.914 285.780 1.00 63.52  ? 305 ASP E CB  1 
ATOM   6250 C CG  . ASP D 2 66  ? 193.914 204.094 284.625 1.00 70.07  ? 305 ASP E CG  1 
ATOM   6251 O OD1 . ASP D 2 66  ? 193.383 205.210 284.456 1.00 71.98  ? 305 ASP E OD1 1 
ATOM   6252 O OD2 . ASP D 2 66  ? 193.699 203.117 283.878 1.00 74.00  ? 305 ASP E OD2 1 
ATOM   6253 N N   . PRO D 2 67  ? 193.413 206.816 287.281 1.00 79.48  ? 306 PRO E N   1 
ATOM   6254 C CA  . PRO D 2 67  ? 192.237 207.187 288.086 1.00 81.77  ? 306 PRO E CA  1 
ATOM   6255 C C   . PRO D 2 67  ? 190.994 206.377 287.762 1.00 83.39  ? 306 PRO E C   1 
ATOM   6256 O O   . PRO D 2 67  ? 190.135 206.208 288.636 1.00 84.50  ? 306 PRO E O   1 
ATOM   6257 C CB  . PRO D 2 67  ? 192.044 208.673 287.755 1.00 83.28  ? 306 PRO E CB  1 
ATOM   6258 C CG  . PRO D 2 67  ? 192.693 208.852 286.423 1.00 79.69  ? 306 PRO E CG  1 
ATOM   6259 C CD  . PRO D 2 67  ? 193.862 207.914 286.409 1.00 81.79  ? 306 PRO E CD  1 
ATOM   6260 N N   . ASP D 2 68  ? 190.867 205.875 286.531 1.00 81.88  ? 307 ASP E N   1 
ATOM   6261 C CA  . ASP D 2 68  ? 189.665 205.137 286.156 1.00 80.62  ? 307 ASP E CA  1 
ATOM   6262 C C   . ASP D 2 68  ? 189.546 203.813 286.901 1.00 80.41  ? 307 ASP E C   1 
ATOM   6263 O O   . ASP D 2 68  ? 188.432 203.327 287.122 1.00 86.04  ? 307 ASP E O   1 
ATOM   6264 C CB  . ASP D 2 68  ? 189.623 204.949 284.630 1.00 86.47  ? 307 ASP E CB  1 
ATOM   6265 C CG  . ASP D 2 68  ? 190.501 203.797 284.117 1.00 89.17  ? 307 ASP E CG  1 
ATOM   6266 O OD1 . ASP D 2 68  ? 191.095 203.026 284.900 1.00 86.75  ? 307 ASP E OD1 1 
ATOM   6267 O OD2 . ASP D 2 68  ? 190.627 203.688 282.880 1.00 89.98  ? 307 ASP E OD2 1 
ATOM   6268 N N   . THR D 2 69  ? 190.670 203.213 287.278 1.00 73.45  ? 308 THR E N   1 
ATOM   6269 C CA  . THR D 2 69  ? 190.670 201.968 288.030 1.00 77.67  ? 308 THR E CA  1 
ATOM   6270 C C   . THR D 2 69  ? 190.827 202.182 289.529 1.00 76.87  ? 308 THR E C   1 
ATOM   6271 O O   . THR D 2 69  ? 190.900 201.200 290.276 1.00 76.33  ? 308 THR E O   1 
ATOM   6272 C CB  . THR D 2 69  ? 191.784 201.048 287.525 1.00 75.38  ? 308 THR E CB  1 
ATOM   6273 O OG1 . THR D 2 69  ? 191.581 199.724 288.031 1.00 77.43  ? 308 THR E OG1 1 
ATOM   6274 C CG2 . THR D 2 69  ? 193.135 201.558 287.981 1.00 76.93  ? 308 THR E CG2 1 
ATOM   6275 N N   . ALA D 2 70  ? 190.879 203.429 289.986 1.00 82.90  ? 309 ALA E N   1 
ATOM   6276 C CA  . ALA D 2 70  ? 191.063 203.698 291.404 1.00 83.44  ? 309 ALA E CA  1 
ATOM   6277 C C   . ALA D 2 70  ? 189.765 203.480 292.168 1.00 86.57  ? 309 ALA E C   1 
ATOM   6278 O O   . ALA D 2 70  ? 188.684 203.857 291.709 1.00 86.20  ? 309 ALA E O   1 
ATOM   6279 C CB  . ALA D 2 70  ? 191.559 205.127 291.612 1.00 86.40  ? 309 ALA E CB  1 
ATOM   6280 N N   . HIS D 2 71  ? 189.880 202.877 293.348 1.00 97.59  ? 310 HIS E N   1 
ATOM   6281 C CA  . HIS D 2 71  ? 188.706 202.607 294.163 1.00 97.28  ? 310 HIS E CA  1 
ATOM   6282 C C   . HIS D 2 71  ? 188.076 203.917 294.631 1.00 97.52  ? 310 HIS E C   1 
ATOM   6283 O O   . HIS D 2 71  ? 188.791 204.884 294.910 1.00 97.05  ? 310 HIS E O   1 
ATOM   6284 C CB  . HIS D 2 71  ? 189.081 201.745 295.367 1.00 91.94  ? 310 HIS E CB  1 
ATOM   6285 C CG  . HIS D 2 71  ? 187.907 201.118 296.051 1.00 92.09  ? 310 HIS E CG  1 
ATOM   6286 N ND1 . HIS D 2 71  ? 187.157 201.780 296.998 1.00 97.26  ? 310 HIS E ND1 1 
ATOM   6287 C CD2 . HIS D 2 71  ? 187.353 199.889 295.926 1.00 91.43  ? 310 HIS E CD2 1 
ATOM   6288 C CE1 . HIS D 2 71  ? 186.192 200.987 297.427 1.00 97.81  ? 310 HIS E CE1 1 
ATOM   6289 N NE2 . HIS D 2 71  ? 186.288 199.834 296.791 1.00 94.84  ? 310 HIS E NE2 1 
ATOM   6290 N N   . PRO D 2 72  ? 186.744 203.983 294.717 1.00 101.84 ? 311 PRO E N   1 
ATOM   6291 C CA  . PRO D 2 72  ? 186.098 205.223 295.179 1.00 100.54 ? 311 PRO E CA  1 
ATOM   6292 C C   . PRO D 2 72  ? 186.557 205.672 296.553 1.00 102.11 ? 311 PRO E C   1 
ATOM   6293 O O   . PRO D 2 72  ? 186.557 206.878 296.825 1.00 106.15 ? 311 PRO E O   1 
ATOM   6294 C CB  . PRO D 2 72  ? 184.608 204.862 295.175 1.00 101.39 ? 311 PRO E CB  1 
ATOM   6295 C CG  . PRO D 2 72  ? 184.492 203.782 294.157 1.00 101.17 ? 311 PRO E CG  1 
ATOM   6296 C CD  . PRO D 2 72  ? 185.762 202.990 294.249 1.00 101.21 ? 311 PRO E CD  1 
ATOM   6297 N N   . ASP D 2 73  ? 186.945 204.747 297.427 1.00 113.30 ? 312 ASP E N   1 
ATOM   6298 C CA  . ASP D 2 73  ? 187.547 205.096 298.707 1.00 116.23 ? 312 ASP E CA  1 
ATOM   6299 C C   . ASP D 2 73  ? 188.917 205.746 298.555 1.00 116.07 ? 312 ASP E C   1 
ATOM   6300 O O   . ASP D 2 73  ? 189.409 206.350 299.515 1.00 115.48 ? 312 ASP E O   1 
ATOM   6301 C CB  . ASP D 2 73  ? 187.658 203.845 299.585 1.00 117.73 ? 312 ASP E CB  1 
ATOM   6302 C CG  . ASP D 2 73  ? 188.086 204.161 301.005 1.00 117.56 ? 312 ASP E CG  1 
ATOM   6303 O OD1 . ASP D 2 73  ? 187.713 205.237 301.514 1.00 118.30 ? 312 ASP E OD1 1 
ATOM   6304 O OD2 . ASP D 2 73  ? 188.796 203.331 301.612 1.00 114.31 ? 312 ASP E OD2 1 
ATOM   6305 N N   . LEU D 2 74  ? 189.535 205.652 297.381 1.00 108.05 ? 313 LEU E N   1 
ATOM   6306 C CA  . LEU D 2 74  ? 190.877 206.163 297.151 1.00 107.78 ? 313 LEU E CA  1 
ATOM   6307 C C   . LEU D 2 74  ? 190.821 207.517 296.457 1.00 112.26 ? 313 LEU E C   1 
ATOM   6308 O O   . LEU D 2 74  ? 189.873 207.815 295.724 1.00 113.52 ? 313 LEU E O   1 
ATOM   6309 C CB  . LEU D 2 74  ? 191.698 205.183 296.312 1.00 106.14 ? 313 LEU E CB  1 
ATOM   6310 C CG  . LEU D 2 74  ? 191.802 203.765 296.872 1.00 107.01 ? 313 LEU E CG  1 
ATOM   6311 C CD1 . LEU D 2 74  ? 192.823 202.961 296.089 1.00 109.53 ? 313 LEU E CD1 1 
ATOM   6312 C CD2 . LEU D 2 74  ? 192.159 203.796 298.348 1.00 107.69 ? 313 LEU E CD2 1 
ATOM   6313 N N   . PHE D 2 75  ? 191.848 208.329 296.696 1.00 106.36 ? 314 PHE E N   1 
ATOM   6314 C CA  . PHE D 2 75  ? 191.949 209.680 296.160 1.00 100.31 ? 314 PHE E CA  1 
ATOM   6315 C C   . PHE D 2 75  ? 193.335 209.878 295.569 1.00 95.79  ? 314 PHE E C   1 
ATOM   6316 O O   . PHE D 2 75  ? 194.337 209.506 296.191 1.00 96.12  ? 314 PHE E O   1 
ATOM   6317 C CB  . PHE D 2 75  ? 191.680 210.724 297.248 1.00 98.39  ? 314 PHE E CB  1 
ATOM   6318 C CG  . PHE D 2 75  ? 192.247 212.078 296.943 1.00 99.51  ? 314 PHE E CG  1 
ATOM   6319 C CD1 . PHE D 2 75  ? 191.639 212.904 296.013 1.00 104.11 ? 314 PHE E CD1 1 
ATOM   6320 C CD2 . PHE D 2 75  ? 193.384 212.529 297.588 1.00 97.42  ? 314 PHE E CD2 1 
ATOM   6321 C CE1 . PHE D 2 75  ? 192.156 214.153 295.732 1.00 103.33 ? 314 PHE E CE1 1 
ATOM   6322 C CE2 . PHE D 2 75  ? 193.908 213.775 297.312 1.00 102.18 ? 314 PHE E CE2 1 
ATOM   6323 C CZ  . PHE D 2 75  ? 193.293 214.589 296.382 1.00 102.23 ? 314 PHE E CZ  1 
ATOM   6324 N N   . LEU D 2 76  ? 193.388 210.474 294.381 1.00 76.43  ? 315 LEU E N   1 
ATOM   6325 C CA  . LEU D 2 76  ? 194.625 210.678 293.641 1.00 74.51  ? 315 LEU E CA  1 
ATOM   6326 C C   . LEU D 2 76  ? 195.003 212.152 293.645 1.00 77.84  ? 315 LEU E C   1 
ATOM   6327 O O   . LEU D 2 76  ? 194.133 213.027 293.605 1.00 82.02  ? 315 LEU E O   1 
ATOM   6328 C CB  . LEU D 2 76  ? 194.490 210.191 292.198 1.00 73.74  ? 315 LEU E CB  1 
ATOM   6329 C CG  . LEU D 2 76  ? 194.961 208.766 291.921 1.00 77.06  ? 315 LEU E CG  1 
ATOM   6330 C CD1 . LEU D 2 76  ? 193.897 207.777 292.343 1.00 78.26  ? 315 LEU E CD1 1 
ATOM   6331 C CD2 . LEU D 2 76  ? 195.306 208.592 290.454 1.00 78.02  ? 315 LEU E CD2 1 
ATOM   6332 N N   . SER D 2 77  ? 196.304 212.420 293.684 1.00 75.26  ? 316 SER E N   1 
ATOM   6333 C CA  . SER D 2 77  ? 196.791 213.789 293.698 1.00 77.95  ? 316 SER E CA  1 
ATOM   6334 C C   . SER D 2 77  ? 196.708 214.393 292.297 1.00 77.97  ? 316 SER E C   1 
ATOM   6335 O O   . SER D 2 77  ? 196.234 213.771 291.343 1.00 80.00  ? 316 SER E O   1 
ATOM   6336 C CB  . SER D 2 77  ? 198.219 213.837 294.231 1.00 79.64  ? 316 SER E CB  1 
ATOM   6337 O OG  . SER D 2 77  ? 199.115 213.210 293.332 1.00 82.81  ? 316 SER E OG  1 
ATOM   6338 N N   . GLU D 2 78  ? 197.181 215.635 292.177 1.00 77.33  ? 317 GLU E N   1 
ATOM   6339 C CA  . GLU D 2 78  ? 197.111 216.328 290.895 1.00 76.84  ? 317 GLU E CA  1 
ATOM   6340 C C   . GLU D 2 78  ? 198.153 215.812 289.912 1.00 78.42  ? 317 GLU E C   1 
ATOM   6341 O O   . GLU D 2 78  ? 197.935 215.872 288.697 1.00 81.68  ? 317 GLU E O   1 
ATOM   6342 C CB  . GLU D 2 78  ? 197.265 217.838 291.101 1.00 80.21  ? 317 GLU E CB  1 
ATOM   6343 C CG  . GLU D 2 78  ? 198.699 218.365 291.262 1.00 84.12  ? 317 GLU E CG  1 
ATOM   6344 C CD  . GLU D 2 78  ? 199.505 217.694 292.372 1.00 86.58  ? 317 GLU E CD  1 
ATOM   6345 O OE1 . GLU D 2 78  ? 198.934 216.939 293.187 1.00 85.69  ? 317 GLU E OE1 1 
ATOM   6346 O OE2 . GLU D 2 78  ? 200.731 217.928 292.425 1.00 86.68  ? 317 GLU E OE2 1 
ATOM   6347 N N   . ASP D 2 79  ? 199.281 215.306 290.404 1.00 72.37  ? 318 ASP E N   1 
ATOM   6348 C CA  . ASP D 2 79  ? 200.332 214.793 289.537 1.00 73.59  ? 318 ASP E CA  1 
ATOM   6349 C C   . ASP D 2 79  ? 200.187 213.306 289.251 1.00 70.36  ? 318 ASP E C   1 
ATOM   6350 O O   . ASP D 2 79  ? 201.028 212.744 288.543 1.00 73.90  ? 318 ASP E O   1 
ATOM   6351 C CB  . ASP D 2 79  ? 201.709 215.068 290.150 1.00 70.47  ? 318 ASP E CB  1 
ATOM   6352 C CG  . ASP D 2 79  ? 201.790 214.662 291.601 1.00 70.67  ? 318 ASP E CG  1 
ATOM   6353 O OD1 . ASP D 2 79  ? 200.732 214.377 292.196 1.00 77.28  ? 318 ASP E OD1 1 
ATOM   6354 O OD2 . ASP D 2 79  ? 202.912 214.627 292.147 1.00 70.70  ? 318 ASP E OD2 1 
ATOM   6355 N N   . ARG D 2 80  ? 199.146 212.666 289.783 1.00 60.21  ? 319 ARG E N   1 
ATOM   6356 C CA  . ARG D 2 80  ? 198.865 211.252 289.533 1.00 63.96  ? 319 ARG E CA  1 
ATOM   6357 C C   . ARG D 2 80  ? 200.033 210.361 289.952 1.00 63.34  ? 319 ARG E C   1 
ATOM   6358 O O   . ARG D 2 80  ? 200.365 209.382 289.281 1.00 68.04  ? 319 ARG E O   1 
ATOM   6359 C CB  . ARG D 2 80  ? 198.498 211.013 288.068 1.00 66.20  ? 319 ARG E CB  1 
ATOM   6360 C CG  . ARG D 2 80  ? 197.009 210.897 287.819 1.00 64.04  ? 319 ARG E CG  1 
ATOM   6361 C CD  . ARG D 2 80  ? 196.311 212.223 288.050 1.00 66.73  ? 319 ARG E CD  1 
ATOM   6362 N NE  . ARG D 2 80  ? 194.952 212.221 287.526 1.00 68.86  ? 319 ARG E NE  1 
ATOM   6363 C CZ  . ARG D 2 80  ? 194.644 212.303 286.240 1.00 70.73  ? 319 ARG E CZ  1 
ATOM   6364 N NH1 . ARG D 2 80  ? 195.579 212.405 285.310 1.00 70.13  ? 319 ARG E NH1 1 
ATOM   6365 N NH2 . ARG D 2 80  ? 193.364 212.284 285.877 1.00 70.62  ? 319 ARG E NH2 1 
ATOM   6366 N N   . ARG D 2 81  ? 200.667 210.706 291.075 1.00 49.63  ? 320 ARG E N   1 
ATOM   6367 C CA  . ARG D 2 81  ? 201.666 209.831 291.676 1.00 46.58  ? 320 ARG E CA  1 
ATOM   6368 C C   . ARG D 2 81  ? 201.480 209.718 293.185 1.00 54.45  ? 320 ARG E C   1 
ATOM   6369 O O   . ARG D 2 81  ? 202.412 209.308 293.886 1.00 58.87  ? 320 ARG E O   1 
ATOM   6370 C CB  . ARG D 2 81  ? 203.090 210.308 291.378 1.00 46.97  ? 320 ARG E CB  1 
ATOM   6371 C CG  . ARG D 2 81  ? 203.502 210.210 289.926 1.00 44.81  ? 320 ARG E CG  1 
ATOM   6372 C CD  . ARG D 2 81  ? 204.962 210.589 289.764 1.00 41.16  ? 320 ARG E CD  1 
ATOM   6373 N NE  . ARG D 2 81  ? 205.160 211.533 288.672 1.00 52.86  ? 320 ARG E NE  1 
ATOM   6374 C CZ  . ARG D 2 81  ? 205.243 211.192 287.395 1.00 57.79  ? 320 ARG E CZ  1 
ATOM   6375 N NH1 . ARG D 2 81  ? 205.159 209.930 287.010 1.00 64.13  ? 320 ARG E NH1 1 
ATOM   6376 N NH2 . ARG D 2 81  ? 205.416 212.141 286.480 1.00 47.61  ? 320 ARG E NH2 1 
ATOM   6377 N N   . SER D 2 82  ? 200.307 210.078 293.700 1.00 67.54  ? 321 SER E N   1 
ATOM   6378 C CA  . SER D 2 82  ? 200.015 209.985 295.123 1.00 70.32  ? 321 SER E CA  1 
ATOM   6379 C C   . SER D 2 82  ? 198.595 209.478 295.299 1.00 70.95  ? 321 SER E C   1 
ATOM   6380 O O   . SER D 2 82  ? 197.671 209.986 294.658 1.00 72.27  ? 321 SER E O   1 
ATOM   6381 C CB  . SER D 2 82  ? 200.186 211.341 295.814 1.00 69.57  ? 321 SER E CB  1 
ATOM   6382 O OG  . SER D 2 82  ? 199.601 211.333 297.105 1.00 76.94  ? 321 SER E OG  1 
ATOM   6383 N N   . VAL D 2 83  ? 198.423 208.482 296.163 1.00 66.37  ? 322 VAL E N   1 
ATOM   6384 C CA  . VAL D 2 83  ? 197.119 207.881 296.415 1.00 69.59  ? 322 VAL E CA  1 
ATOM   6385 C C   . VAL D 2 83  ? 196.920 207.758 297.917 1.00 76.43  ? 322 VAL E C   1 
ATOM   6386 O O   . VAL D 2 83  ? 197.792 207.242 298.624 1.00 71.52  ? 322 VAL E O   1 
ATOM   6387 C CB  . VAL D 2 83  ? 196.985 206.503 295.740 1.00 74.73  ? 322 VAL E CB  1 
ATOM   6388 C CG1 . VAL D 2 83  ? 195.802 205.739 296.310 1.00 73.57  ? 322 VAL E CG1 1 
ATOM   6389 C CG2 . VAL D 2 83  ? 196.835 206.669 294.248 1.00 78.13  ? 322 VAL E CG2 1 
ATOM   6390 N N   . ARG D 2 84  ? 195.772 208.229 298.403 1.00 101.16 ? 323 ARG E N   1 
ATOM   6391 C CA  . ARG D 2 84  ? 195.403 208.055 299.804 1.00 96.84  ? 323 ARG E CA  1 
ATOM   6392 C C   . ARG D 2 84  ? 193.984 207.513 299.909 1.00 94.12  ? 323 ARG E C   1 
ATOM   6393 O O   . ARG D 2 84  ? 193.343 207.251 298.889 1.00 95.18  ? 323 ARG E O   1 
ATOM   6394 C CB  . ARG D 2 84  ? 195.527 209.373 300.570 1.00 95.56  ? 323 ARG E CB  1 
ATOM   6395 C CG  . ARG D 2 84  ? 194.548 210.438 300.123 1.00 94.13  ? 323 ARG E CG  1 
ATOM   6396 C CD  . ARG D 2 84  ? 194.995 211.817 300.564 1.00 92.84  ? 323 ARG E CD  1 
ATOM   6397 N NE  . ARG D 2 84  ? 195.505 211.817 301.928 1.00 95.66  ? 323 ARG E NE  1 
ATOM   6398 C CZ  . ARG D 2 84  ? 196.610 212.439 302.313 1.00 96.01  ? 323 ARG E CZ  1 
ATOM   6399 N NH1 . ARG D 2 84  ? 197.353 213.120 301.457 1.00 95.28  ? 323 ARG E NH1 1 
ATOM   6400 N NH2 . ARG D 2 84  ? 196.976 212.381 303.591 1.00 96.62  ? 323 ARG E NH2 1 
ATOM   6401 N N   . ARG D 2 85  ? 193.480 207.345 301.127 1.00 104.85 ? 324 ARG E N   1 
ATOM   6402 C CA  . ARG D 2 85  ? 192.126 206.863 301.351 1.00 108.51 ? 324 ARG E CA  1 
ATOM   6403 C C   . ARG D 2 85  ? 191.318 207.914 302.097 1.00 111.83 ? 324 ARG E C   1 
ATOM   6404 O O   . ARG D 2 85  ? 191.869 208.699 302.875 1.00 110.45 ? 324 ARG E O   1 
ATOM   6405 C CB  . ARG D 2 85  ? 192.114 205.557 302.150 1.00 110.14 ? 324 ARG E CB  1 
ATOM   6406 C CG  . ARG D 2 85  ? 192.637 205.705 303.565 1.00 108.92 ? 324 ARG E CG  1 
ATOM   6407 C CD  . ARG D 2 85  ? 191.790 204.923 304.552 1.00 105.92 ? 324 ARG E CD  1 
ATOM   6408 N NE  . ARG D 2 85  ? 192.173 205.190 305.933 1.00 102.22 ? 324 ARG E NE  1 
ATOM   6409 C CZ  . ARG D 2 85  ? 191.891 206.308 306.588 1.00 106.29 ? 324 ARG E CZ  1 
ATOM   6410 N NH1 . ARG D 2 85  ? 191.211 207.290 306.020 1.00 109.02 ? 324 ARG E NH1 1 
ATOM   6411 N NH2 . ARG D 2 85  ? 192.300 206.443 307.846 1.00 106.51 ? 324 ARG E NH2 1 
ATOM   6412 N N   . CYS D 2 86  ? 190.014 207.931 301.848 1.00 136.91 ? 325 CYS E N   1 
ATOM   6413 C CA  . CYS D 2 86  ? 189.105 208.777 302.607 1.00 137.83 ? 325 CYS E CA  1 
ATOM   6414 C C   . CYS D 2 86  ? 187.727 208.128 302.601 1.00 137.51 ? 325 CYS E C   1 
ATOM   6415 O O   . CYS D 2 86  ? 187.047 208.122 301.566 1.00 138.03 ? 325 CYS E O   1 
ATOM   6416 C CB  . CYS D 2 86  ? 189.054 210.192 302.029 1.00 138.84 ? 325 CYS E CB  1 
ATOM   6417 S SG  . CYS D 2 86  ? 187.528 211.096 302.378 1.00 138.91 ? 325 CYS E SG  1 
ATOM   6418 N N   . PRO D 2 87  ? 187.296 207.548 303.721 1.00 151.52 ? 326 PRO E N   1 
ATOM   6419 C CA  . PRO D 2 87  ? 186.011 206.829 303.753 1.00 154.91 ? 326 PRO E CA  1 
ATOM   6420 C C   . PRO D 2 87  ? 184.847 207.758 303.442 1.00 157.44 ? 326 PRO E C   1 
ATOM   6421 O O   . PRO D 2 87  ? 184.842 208.925 303.841 1.00 156.77 ? 326 PRO E O   1 
ATOM   6422 C CB  . PRO D 2 87  ? 185.939 206.289 305.187 1.00 153.52 ? 326 PRO E CB  1 
ATOM   6423 C CG  . PRO D 2 87  ? 187.345 206.358 305.707 1.00 151.52 ? 326 PRO E CG  1 
ATOM   6424 C CD  . PRO D 2 87  ? 187.975 207.527 305.026 1.00 150.63 ? 326 PRO E CD  1 
ATOM   6425 N N   . PHE D 2 88  ? 183.856 207.226 302.724 1.00 185.85 ? 327 PHE E N   1 
ATOM   6426 C CA  . PHE D 2 88  ? 182.627 207.943 302.383 1.00 185.04 ? 327 PHE E CA  1 
ATOM   6427 C C   . PHE D 2 88  ? 182.932 209.245 301.639 1.00 185.04 ? 327 PHE E C   1 
ATOM   6428 O O   . PHE D 2 88  ? 182.450 210.325 301.988 1.00 185.89 ? 327 PHE E O   1 
ATOM   6429 C CB  . PHE D 2 88  ? 181.783 208.202 303.635 1.00 185.65 ? 327 PHE E CB  1 
ATOM   6430 C CG  . PHE D 2 88  ? 181.022 206.998 304.113 1.00 186.82 ? 327 PHE E CG  1 
ATOM   6431 C CD1 . PHE D 2 88  ? 180.830 205.908 303.280 1.00 186.55 ? 327 PHE E CD1 1 
ATOM   6432 C CD2 . PHE D 2 88  ? 180.499 206.956 305.394 1.00 186.39 ? 327 PHE E CD2 1 
ATOM   6433 C CE1 . PHE D 2 88  ? 180.131 204.798 303.716 1.00 185.88 ? 327 PHE E CE1 1 
ATOM   6434 C CE2 . PHE D 2 88  ? 179.799 205.849 305.837 1.00 185.52 ? 327 PHE E CE2 1 
ATOM   6435 C CZ  . PHE D 2 88  ? 179.615 204.769 304.996 1.00 185.61 ? 327 PHE E CZ  1 
ATOM   6436 N N   . ARG D 2 89  ? 183.752 209.123 300.593 1.00 159.94 ? 328 ARG E N   1 
ATOM   6437 C CA  . ARG D 2 89  ? 184.086 210.257 299.744 1.00 159.93 ? 328 ARG E CA  1 
ATOM   6438 C C   . ARG D 2 89  ? 183.427 210.210 298.374 1.00 160.64 ? 328 ARG E C   1 
ATOM   6439 O O   . ARG D 2 89  ? 183.361 211.246 297.706 1.00 161.20 ? 328 ARG E O   1 
ATOM   6440 C CB  . ARG D 2 89  ? 185.607 210.361 299.559 1.00 157.87 ? 328 ARG E CB  1 
ATOM   6441 C CG  . ARG D 2 89  ? 186.142 209.628 298.344 1.00 158.23 ? 328 ARG E CG  1 
ATOM   6442 C CD  . ARG D 2 89  ? 187.657 209.703 298.274 1.00 156.62 ? 328 ARG E CD  1 
ATOM   6443 N NE  . ARG D 2 89  ? 188.147 209.510 296.915 1.00 156.37 ? 328 ARG E NE  1 
ATOM   6444 C CZ  . ARG D 2 89  ? 188.447 210.495 296.080 1.00 154.56 ? 328 ARG E CZ  1 
ATOM   6445 N NH1 . ARG D 2 89  ? 188.321 211.763 296.435 1.00 155.22 ? 328 ARG E NH1 1 
ATOM   6446 N NH2 . ARG D 2 89  ? 188.885 210.201 294.860 1.00 153.32 ? 328 ARG E NH2 1 
ATOM   6447 N N   . HIS D 2 90  ? 182.942 209.049 297.944 1.00 180.39 ? 329 HIS E N   1 
ATOM   6448 C CA  . HIS D 2 90  ? 182.274 208.886 296.656 1.00 181.16 ? 329 HIS E CA  1 
ATOM   6449 C C   . HIS D 2 90  ? 181.016 208.046 296.818 1.00 182.20 ? 329 HIS E C   1 
ATOM   6450 O O   . HIS D 2 90  ? 180.709 207.168 296.009 1.00 182.35 ? 329 HIS E O   1 
ATOM   6451 C CB  . HIS D 2 90  ? 183.215 208.264 295.628 1.00 180.47 ? 329 HIS E CB  1 
ATOM   6452 C CG  . HIS D 2 90  ? 183.990 209.268 294.833 1.00 181.14 ? 329 HIS E CG  1 
ATOM   6453 N ND1 . HIS D 2 90  ? 185.326 209.524 295.055 1.00 180.47 ? 329 HIS E ND1 1 
ATOM   6454 C CD2 . HIS D 2 90  ? 183.614 210.084 293.820 1.00 180.68 ? 329 HIS E CD2 1 
ATOM   6455 C CE1 . HIS D 2 90  ? 185.741 210.451 294.211 1.00 179.74 ? 329 HIS E CE1 1 
ATOM   6456 N NE2 . HIS D 2 90  ? 184.722 210.808 293.450 1.00 180.29 ? 329 HIS E NE2 1 
ATOM   6457 N N   . LEU D 2 91  ? 180.265 208.312 297.884 1.00 209.48 ? 330 LEU E N   1 
ATOM   6458 C CA  . LEU D 2 91  ? 179.025 207.591 298.162 1.00 210.71 ? 330 LEU E CA  1 
ATOM   6459 C C   . LEU D 2 91  ? 177.886 208.296 297.437 1.00 211.27 ? 330 LEU E C   1 
ATOM   6460 O O   . LEU D 2 91  ? 177.425 209.359 297.860 1.00 211.81 ? 330 LEU E O   1 
ATOM   6461 C CB  . LEU D 2 91  ? 178.770 207.520 299.663 1.00 209.73 ? 330 LEU E CB  1 
ATOM   6462 C CG  . LEU D 2 91  ? 177.510 206.772 300.103 1.00 209.61 ? 330 LEU E CG  1 
ATOM   6463 C CD1 . LEU D 2 91  ? 177.603 205.299 299.735 1.00 209.56 ? 330 LEU E CD1 1 
ATOM   6464 C CD2 . LEU D 2 91  ? 177.278 206.942 301.596 1.00 209.03 ? 330 LEU E CD2 1 
ATOM   6465 N N   . GLY D 2 92  ? 177.428 207.703 296.337 1.00 210.12 ? 331 GLY E N   1 
ATOM   6466 C CA  . GLY D 2 92  ? 176.354 208.297 295.567 1.00 208.82 ? 331 GLY E CA  1 
ATOM   6467 C C   . GLY D 2 92  ? 176.776 209.425 294.655 1.00 208.77 ? 331 GLY E C   1 
ATOM   6468 O O   . GLY D 2 92  ? 175.918 210.066 294.042 1.00 209.27 ? 331 GLY E O   1 
ATOM   6469 N N   . GLU D 2 93  ? 178.075 209.688 294.544 1.00 198.27 ? 332 GLU E N   1 
ATOM   6470 C CA  . GLU D 2 93  ? 178.566 210.754 293.688 1.00 197.45 ? 332 GLU E CA  1 
ATOM   6471 C C   . GLU D 2 93  ? 178.608 210.287 292.234 1.00 196.62 ? 332 GLU E C   1 
ATOM   6472 O O   . GLU D 2 93  ? 178.457 209.101 291.925 1.00 196.11 ? 332 GLU E O   1 
ATOM   6473 C CB  . GLU D 2 93  ? 179.941 211.223 294.159 1.00 197.13 ? 332 GLU E CB  1 
ATOM   6474 C CG  . GLU D 2 93  ? 179.909 212.034 295.444 1.00 197.70 ? 332 GLU E CG  1 
ATOM   6475 C CD  . GLU D 2 93  ? 181.215 212.758 295.709 1.00 198.05 ? 332 GLU E CD  1 
ATOM   6476 O OE1 . GLU D 2 93  ? 182.140 212.643 294.878 1.00 198.60 ? 332 GLU E OE1 1 
ATOM   6477 O OE2 . GLU D 2 93  ? 181.315 213.444 296.748 1.00 198.17 ? 332 GLU E OE2 1 
ATOM   6478 N N   . SER D 2 94  ? 178.819 211.237 291.325 1.00 183.44 ? 333 SER E N   1 
ATOM   6479 C CA  . SER D 2 94  ? 178.825 210.936 289.899 1.00 182.99 ? 333 SER E CA  1 
ATOM   6480 C C   . SER D 2 94  ? 180.091 210.188 289.503 1.00 182.08 ? 333 SER E C   1 
ATOM   6481 O O   . SER D 2 94  ? 181.122 210.806 289.219 1.00 181.78 ? 333 SER E O   1 
ATOM   6482 C CB  . SER D 2 94  ? 178.690 212.222 289.081 1.00 183.21 ? 333 SER E CB  1 
ATOM   6483 O OG  . SER D 2 94  ? 178.745 211.951 287.692 1.00 182.93 ? 333 SER E OG  1 
ATOM   6484 N N   . VAL D 2 95  ? 180.021 208.857 289.483 1.00 150.23 ? 334 VAL E N   1 
ATOM   6485 C CA  . VAL D 2 95  ? 181.131 208.015 289.065 1.00 148.45 ? 334 VAL E CA  1 
ATOM   6486 C C   . VAL D 2 95  ? 180.609 207.037 288.021 1.00 145.96 ? 334 VAL E C   1 
ATOM   6487 O O   . VAL D 2 95  ? 179.619 206.342 288.269 1.00 145.07 ? 334 VAL E O   1 
ATOM   6488 C CB  . VAL D 2 95  ? 181.771 207.254 290.239 1.00 146.88 ? 334 VAL E CB  1 
ATOM   6489 C CG1 . VAL D 2 95  ? 182.649 206.124 289.726 1.00 145.05 ? 334 VAL E CG1 1 
ATOM   6490 C CG2 . VAL D 2 95  ? 182.576 208.203 291.108 1.00 146.82 ? 334 VAL E CG2 1 
ATOM   6491 N N   . PRO D 2 96  ? 181.221 206.948 286.845 1.00 125.63 ? 335 PRO E N   1 
ATOM   6492 C CA  . PRO D 2 96  ? 180.742 206.004 285.833 1.00 124.37 ? 335 PRO E CA  1 
ATOM   6493 C C   . PRO D 2 96  ? 180.982 204.564 286.257 1.00 123.66 ? 335 PRO E C   1 
ATOM   6494 O O   . PRO D 2 96  ? 181.882 204.253 287.039 1.00 121.33 ? 335 PRO E O   1 
ATOM   6495 C CB  . PRO D 2 96  ? 181.568 206.362 284.594 1.00 125.72 ? 335 PRO E CB  1 
ATOM   6496 C CG  . PRO D 2 96  ? 182.820 206.956 285.145 1.00 127.11 ? 335 PRO E CG  1 
ATOM   6497 C CD  . PRO D 2 96  ? 182.417 207.684 286.398 1.00 127.56 ? 335 PRO E CD  1 
ATOM   6498 N N   . ASP D 2 97  ? 180.143 203.677 285.723 1.00 114.36 ? 336 ASP E N   1 
ATOM   6499 C CA  . ASP D 2 97  ? 180.246 202.244 285.995 1.00 112.14 ? 336 ASP E CA  1 
ATOM   6500 C C   . ASP D 2 97  ? 181.243 201.631 285.016 1.00 112.61 ? 336 ASP E C   1 
ATOM   6501 O O   . ASP D 2 97  ? 180.907 200.823 284.147 1.00 111.82 ? 336 ASP E O   1 
ATOM   6502 C CB  . ASP D 2 97  ? 178.877 201.583 285.903 1.00 114.59 ? 336 ASP E CB  1 
ATOM   6503 C CG  . ASP D 2 97  ? 178.118 201.980 284.651 1.00 116.70 ? 336 ASP E CG  1 
ATOM   6504 O OD1 . ASP D 2 97  ? 178.719 202.618 283.761 1.00 117.91 ? 336 ASP E OD1 1 
ATOM   6505 O OD2 . ASP D 2 97  ? 176.916 201.654 284.556 1.00 117.23 ? 336 ASP E OD2 1 
ATOM   6506 N N   . ASN D 2 98  ? 182.503 202.029 285.169 1.00 102.51 ? 337 ASN E N   1 
ATOM   6507 C CA  . ASN D 2 98  ? 183.568 201.534 284.310 1.00 99.78  ? 337 ASN E CA  1 
ATOM   6508 C C   . ASN D 2 98  ? 183.849 200.074 284.634 1.00 99.58  ? 337 ASN E C   1 
ATOM   6509 O O   . ASN D 2 98  ? 184.071 199.745 285.807 1.00 100.95 ? 337 ASN E O   1 
ATOM   6510 C CB  . ASN D 2 98  ? 184.831 202.356 284.492 1.00 101.12 ? 337 ASN E CB  1 
ATOM   6511 C CG  . ASN D 2 98  ? 185.081 202.721 285.939 1.00 102.02 ? 337 ASN E CG  1 
ATOM   6512 O OD1 . ASN D 2 98  ? 184.181 202.642 286.774 1.00 100.98 ? 337 ASN E OD1 1 
ATOM   6513 N ND2 . ASN D 2 98  ? 186.309 203.121 286.245 1.00 101.17 ? 337 ASN E ND2 1 
ATOM   6514 N N   . PRO D 2 99  ? 183.839 199.173 283.648 1.00 90.46  ? 338 PRO E N   1 
ATOM   6515 C CA  . PRO D 2 99  ? 184.151 197.764 283.940 1.00 93.42  ? 338 PRO E CA  1 
ATOM   6516 C C   . PRO D 2 99  ? 185.567 197.535 284.447 1.00 95.04  ? 338 PRO E C   1 
ATOM   6517 O O   . PRO D 2 99  ? 185.825 196.476 285.033 1.00 95.19  ? 338 PRO E O   1 
ATOM   6518 C CB  . PRO D 2 99  ? 183.915 197.060 282.595 1.00 93.23  ? 338 PRO E CB  1 
ATOM   6519 C CG  . PRO D 2 99  ? 183.887 198.148 281.570 1.00 91.31  ? 338 PRO E CG  1 
ATOM   6520 C CD  . PRO D 2 99  ? 183.371 199.364 282.267 1.00 88.85  ? 338 PRO E CD  1 
ATOM   6521 N N   . GLU D 2 100 ? 186.490 198.474 284.247 1.00 90.22  ? 339 GLU E N   1 
ATOM   6522 C CA  . GLU D 2 100 ? 187.856 198.323 284.730 1.00 86.35  ? 339 GLU E CA  1 
ATOM   6523 C C   . GLU D 2 100 ? 188.063 198.935 286.109 1.00 88.81  ? 339 GLU E C   1 
ATOM   6524 O O   . GLU D 2 100 ? 189.170 199.391 286.409 1.00 92.96  ? 339 GLU E O   1 
ATOM   6525 C CB  . GLU D 2 100 ? 188.870 198.943 283.754 1.00 88.36  ? 339 GLU E CB  1 
ATOM   6526 C CG  . GLU D 2 100 ? 188.586 200.361 283.216 1.00 93.02  ? 339 GLU E CG  1 
ATOM   6527 C CD  . GLU D 2 100 ? 187.353 200.486 282.334 1.00 95.56  ? 339 GLU E CD  1 
ATOM   6528 O OE1 . GLU D 2 100 ? 186.555 199.533 282.260 1.00 92.09  ? 339 GLU E OE1 1 
ATOM   6529 O OE2 . GLU D 2 100 ? 187.184 201.554 281.709 1.00 97.73  ? 339 GLU E OE2 1 
ATOM   6530 N N   . ARG D 2 101 ? 187.035 198.953 286.949 1.00 85.38  ? 340 ARG E N   1 
ATOM   6531 C CA  . ARG D 2 101 ? 187.111 199.645 288.227 1.00 83.07  ? 340 ARG E CA  1 
ATOM   6532 C C   . ARG D 2 101 ? 187.310 198.666 289.376 1.00 85.28  ? 340 ARG E C   1 
ATOM   6533 O O   . ARG D 2 101 ? 186.650 197.626 289.449 1.00 87.61  ? 340 ARG E O   1 
ATOM   6534 C CB  . ARG D 2 101 ? 185.838 200.458 288.458 1.00 83.43  ? 340 ARG E CB  1 
ATOM   6535 C CG  . ARG D 2 101 ? 185.729 201.069 289.840 1.00 86.43  ? 340 ARG E CG  1 
ATOM   6536 C CD  . ARG D 2 101 ? 186.655 202.258 289.989 1.00 87.33  ? 340 ARG E CD  1 
ATOM   6537 N NE  . ARG D 2 101 ? 186.116 203.456 289.357 1.00 93.03  ? 340 ARG E NE  1 
ATOM   6538 C CZ  . ARG D 2 101 ? 186.782 204.594 289.221 1.00 89.56  ? 340 ARG E CZ  1 
ATOM   6539 N NH1 . ARG D 2 101 ? 188.024 204.724 289.654 1.00 85.19  ? 340 ARG E NH1 1 
ATOM   6540 N NH2 . ARG D 2 101 ? 186.187 205.626 288.629 1.00 87.45  ? 340 ARG E NH2 1 
ATOM   6541 N N   . PHE D 2 102 ? 188.230 199.006 290.276 1.00 78.31  ? 341 PHE E N   1 
ATOM   6542 C CA  . PHE D 2 102 ? 188.377 198.285 291.536 1.00 76.38  ? 341 PHE E CA  1 
ATOM   6543 C C   . PHE D 2 102 ? 187.305 198.785 292.494 1.00 81.35  ? 341 PHE E C   1 
ATOM   6544 O O   . PHE D 2 102 ? 187.375 199.920 292.974 1.00 81.75  ? 341 PHE E O   1 
ATOM   6545 C CB  . PHE D 2 102 ? 189.766 198.501 292.128 1.00 77.09  ? 341 PHE E CB  1 
ATOM   6546 C CG  . PHE D 2 102 ? 190.793 197.517 291.657 1.00 75.46  ? 341 PHE E CG  1 
ATOM   6547 C CD1 . PHE D 2 102 ? 191.119 197.417 290.319 1.00 79.92  ? 341 PHE E CD1 1 
ATOM   6548 C CD2 . PHE D 2 102 ? 191.443 196.700 292.560 1.00 75.41  ? 341 PHE E CD2 1 
ATOM   6549 C CE1 . PHE D 2 102 ? 192.073 196.517 289.893 1.00 81.79  ? 341 PHE E CE1 1 
ATOM   6550 C CE2 . PHE D 2 102 ? 192.397 195.801 292.140 1.00 77.20  ? 341 PHE E CE2 1 
ATOM   6551 C CZ  . PHE D 2 102 ? 192.711 195.708 290.805 1.00 80.51  ? 341 PHE E CZ  1 
ATOM   6552 N N   . ASP D 2 103 ? 186.305 197.947 292.773 1.00 96.44  ? 342 ASP E N   1 
ATOM   6553 C CA  . ASP D 2 103 ? 185.199 198.342 293.637 1.00 97.67  ? 342 ASP E CA  1 
ATOM   6554 C C   . ASP D 2 103 ? 184.974 197.347 294.770 1.00 92.52  ? 342 ASP E C   1 
ATOM   6555 O O   . ASP D 2 103 ? 183.899 197.339 295.376 1.00 92.93  ? 342 ASP E O   1 
ATOM   6556 C CB  . ASP D 2 103 ? 183.916 198.519 292.821 1.00 100.17 ? 342 ASP E CB  1 
ATOM   6557 C CG  . ASP D 2 103 ? 183.792 197.501 291.708 1.00 98.28  ? 342 ASP E CG  1 
ATOM   6558 O OD1 . ASP D 2 103 ? 184.319 196.381 291.866 1.00 95.85  ? 342 ASP E OD1 1 
ATOM   6559 O OD2 . ASP D 2 103 ? 183.174 197.824 290.672 1.00 96.86  ? 342 ASP E OD2 1 
ATOM   6560 N N   . SER D 2 104 ? 185.963 196.509 295.065 1.00 80.67  ? 343 SER E N   1 
ATOM   6561 C CA  . SER D 2 104 ? 185.880 195.561 296.167 1.00 82.15  ? 343 SER E CA  1 
ATOM   6562 C C   . SER D 2 104 ? 186.934 195.817 297.230 1.00 83.82  ? 343 SER E C   1 
ATOM   6563 O O   . SER D 2 104 ? 186.600 195.923 298.416 1.00 83.23  ? 343 SER E O   1 
ATOM   6564 C CB  . SER D 2 104 ? 186.005 194.127 295.632 1.00 85.20  ? 343 SER E CB  1 
ATOM   6565 O OG  . SER D 2 104 ? 185.013 193.865 294.654 1.00 84.39  ? 343 SER E OG  1 
ATOM   6566 N N   . GLN D 2 105 ? 188.200 195.921 296.839 1.00 85.09  ? 344 GLN E N   1 
ATOM   6567 C CA  . GLN D 2 105 ? 189.289 196.215 297.751 1.00 82.15  ? 344 GLN E CA  1 
ATOM   6568 C C   . GLN D 2 105 ? 189.864 197.597 297.460 1.00 86.37  ? 344 GLN E C   1 
ATOM   6569 O O   . GLN D 2 105 ? 189.784 198.082 296.328 1.00 90.73  ? 344 GLN E O   1 
ATOM   6570 C CB  . GLN D 2 105 ? 190.410 195.176 297.634 1.00 81.28  ? 344 GLN E CB  1 
ATOM   6571 C CG  . GLN D 2 105 ? 189.946 193.786 297.268 1.00 82.10  ? 344 GLN E CG  1 
ATOM   6572 C CD  . GLN D 2 105 ? 191.068 192.942 296.702 1.00 85.29  ? 344 GLN E CD  1 
ATOM   6573 O OE1 . GLN D 2 105 ? 191.902 192.421 297.441 1.00 90.02  ? 344 GLN E OE1 1 
ATOM   6574 N NE2 . GLN D 2 105 ? 191.099 192.808 295.382 1.00 86.86  ? 344 GLN E NE2 1 
ATOM   6575 N N   . PRO D 2 106 ? 190.453 198.255 298.455 1.00 78.61  ? 345 PRO E N   1 
ATOM   6576 C CA  . PRO D 2 106 ? 191.043 199.579 298.213 1.00 83.52  ? 345 PRO E CA  1 
ATOM   6577 C C   . PRO D 2 106 ? 192.358 199.503 297.452 1.00 77.47  ? 345 PRO E C   1 
ATOM   6578 O O   . PRO D 2 106 ? 193.434 199.502 298.057 1.00 73.68  ? 345 PRO E O   1 
ATOM   6579 C CB  . PRO D 2 106 ? 191.246 200.140 299.628 1.00 80.93  ? 345 PRO E CB  1 
ATOM   6580 C CG  . PRO D 2 106 ? 190.390 199.293 300.519 1.00 76.48  ? 345 PRO E CG  1 
ATOM   6581 C CD  . PRO D 2 106 ? 190.383 197.941 299.890 1.00 73.57  ? 345 PRO E CD  1 
ATOM   6582 N N   . CYS D 2 107 ? 192.281 199.423 296.123 1.00 81.92  ? 346 CYS E N   1 
ATOM   6583 C CA  . CYS D 2 107 ? 193.465 199.275 295.289 1.00 80.61  ? 346 CYS E CA  1 
ATOM   6584 C C   . CYS D 2 107 ? 193.360 200.159 294.053 1.00 84.24  ? 346 CYS E C   1 
ATOM   6585 O O   . CYS D 2 107 ? 192.308 200.725 293.748 1.00 85.31  ? 346 CYS E O   1 
ATOM   6586 C CB  . CYS D 2 107 ? 193.678 197.820 294.858 1.00 88.87  ? 346 CYS E CB  1 
ATOM   6587 S SG  . CYS D 2 107 ? 193.122 196.576 296.033 1.00 112.81 ? 346 CYS E SG  1 
ATOM   6588 N N   . VAL D 2 108 ? 194.481 200.257 293.343 1.00 72.17  ? 347 VAL E N   1 
ATOM   6589 C CA  . VAL D 2 108 ? 194.609 201.065 292.135 1.00 69.24  ? 347 VAL E CA  1 
ATOM   6590 C C   . VAL D 2 108 ? 195.745 200.490 291.294 1.00 70.20  ? 347 VAL E C   1 
ATOM   6591 O O   . VAL D 2 108 ? 196.725 199.954 291.825 1.00 70.89  ? 347 VAL E O   1 
ATOM   6592 C CB  . VAL D 2 108 ? 194.838 202.553 292.484 1.00 60.16  ? 347 VAL E CB  1 
ATOM   6593 C CG1 . VAL D 2 108 ? 196.090 202.717 293.328 1.00 67.23  ? 347 VAL E CG1 1 
ATOM   6594 C CG2 . VAL D 2 108 ? 194.907 203.407 291.230 1.00 59.31  ? 347 VAL E CG2 1 
ATOM   6595 N N   . LEU D 2 109 ? 195.610 200.598 289.977 1.00 48.44  ? 348 LEU E N   1 
ATOM   6596 C CA  . LEU D 2 109 ? 196.535 199.980 289.041 1.00 43.33  ? 348 LEU E CA  1 
ATOM   6597 C C   . LEU D 2 109 ? 197.384 201.031 288.339 1.00 42.94  ? 348 LEU E C   1 
ATOM   6598 O O   . LEU D 2 109 ? 196.918 202.131 288.031 1.00 52.89  ? 348 LEU E O   1 
ATOM   6599 C CB  . LEU D 2 109 ? 195.779 199.157 287.998 1.00 47.73  ? 348 LEU E CB  1 
ATOM   6600 C CG  . LEU D 2 109 ? 195.311 197.768 288.421 1.00 53.02  ? 348 LEU E CG  1 
ATOM   6601 C CD1 . LEU D 2 109 ? 194.484 197.125 287.321 1.00 53.88  ? 348 LEU E CD1 1 
ATOM   6602 C CD2 . LEU D 2 109 ? 196.500 196.907 288.765 1.00 48.93  ? 348 LEU E CD2 1 
ATOM   6603 N N   . GLY D 2 110 ? 198.641 200.679 288.087 1.00 34.72  ? 349 GLY E N   1 
ATOM   6604 C CA  . GLY D 2 110 ? 199.497 201.541 287.299 1.00 30.13  ? 349 GLY E CA  1 
ATOM   6605 C C   . GLY D 2 110 ? 199.051 201.598 285.851 1.00 37.52  ? 349 GLY E C   1 
ATOM   6606 O O   . GLY D 2 110 ? 198.488 200.649 285.308 1.00 44.74  ? 349 GLY E O   1 
ATOM   6607 N N   . ARG D 2 111 ? 199.303 202.741 285.216 1.00 40.59  ? 350 ARG E N   1 
ATOM   6608 C CA  . ARG D 2 111 ? 198.910 202.918 283.824 1.00 40.18  ? 350 ARG E CA  1 
ATOM   6609 C C   . ARG D 2 111 ? 199.777 202.118 282.863 1.00 44.65  ? 350 ARG E C   1 
ATOM   6610 O O   . ARG D 2 111 ? 199.324 201.802 281.758 1.00 48.46  ? 350 ARG E O   1 
ATOM   6611 C CB  . ARG D 2 111 ? 198.961 204.399 283.447 1.00 41.29  ? 350 ARG E CB  1 
ATOM   6612 C CG  . ARG D 2 111 ? 198.169 204.756 282.205 1.00 41.57  ? 350 ARG E CG  1 
ATOM   6613 C CD  . ARG D 2 111 ? 198.221 206.248 281.931 1.00 47.13  ? 350 ARG E CD  1 
ATOM   6614 N NE  . ARG D 2 111 ? 199.477 206.841 282.373 1.00 50.77  ? 350 ARG E NE  1 
ATOM   6615 C CZ  . ARG D 2 111 ? 200.500 207.111 281.575 1.00 47.75  ? 350 ARG E CZ  1 
ATOM   6616 N NH1 . ARG D 2 111 ? 200.455 206.845 280.280 1.00 48.92  ? 350 ARG E NH1 1 
ATOM   6617 N NH2 . ARG D 2 111 ? 201.597 207.659 282.088 1.00 40.78  ? 350 ARG E NH2 1 
ATOM   6618 N N   . GLU D 2 112 ? 201.000 201.779 283.255 1.00 45.13  ? 351 GLU E N   1 
ATOM   6619 C CA  . GLU D 2 112 ? 201.921 201.101 282.358 1.00 37.13  ? 351 GLU E CA  1 
ATOM   6620 C C   . GLU D 2 112 ? 201.598 199.616 282.252 1.00 41.05  ? 351 GLU E C   1 
ATOM   6621 O O   . GLU D 2 112 ? 201.223 198.965 283.231 1.00 47.05  ? 351 GLU E O   1 
ATOM   6622 C CB  . GLU D 2 112 ? 203.359 201.281 282.839 1.00 41.71  ? 351 GLU E CB  1 
ATOM   6623 C CG  . GLU D 2 112 ? 203.691 202.696 283.264 1.00 42.77  ? 351 GLU E CG  1 
ATOM   6624 C CD  . GLU D 2 112 ? 204.256 203.520 282.128 1.00 49.02  ? 351 GLU E CD  1 
ATOM   6625 O OE1 . GLU D 2 112 ? 204.217 203.046 280.974 1.00 54.91  ? 351 GLU E OE1 1 
ATOM   6626 O OE2 . GLU D 2 112 ? 204.738 204.642 282.388 1.00 50.14  ? 351 GLU E OE2 1 
ATOM   6627 N N   . SER D 2 113 ? 201.749 199.085 281.044 1.00 33.16  ? 352 SER E N   1 
ATOM   6628 C CA  . SER D 2 113 ? 201.627 197.658 280.781 1.00 41.15  ? 352 SER E CA  1 
ATOM   6629 C C   . SER D 2 113 ? 202.976 197.133 280.317 1.00 40.05  ? 352 SER E C   1 
ATOM   6630 O O   . SER D 2 113 ? 203.614 197.734 279.448 1.00 42.95  ? 352 SER E O   1 
ATOM   6631 C CB  . SER D 2 113 ? 200.553 197.372 279.729 1.00 41.88  ? 352 SER E CB  1 
ATOM   6632 O OG  . SER D 2 113 ? 199.265 197.327 280.311 1.00 41.62  ? 352 SER E OG  1 
ATOM   6633 N N   . PHE D 2 114 ? 203.405 196.017 280.895 1.00 40.24  ? 353 PHE E N   1 
ATOM   6634 C CA  . PHE D 2 114 ? 204.693 195.416 280.587 1.00 44.54  ? 353 PHE E CA  1 
ATOM   6635 C C   . PHE D 2 114 ? 204.480 194.077 279.898 1.00 50.49  ? 353 PHE E C   1 
ATOM   6636 O O   . PHE D 2 114 ? 203.664 193.266 280.347 1.00 58.93  ? 353 PHE E O   1 
ATOM   6637 C CB  . PHE D 2 114 ? 205.524 195.234 281.856 1.00 41.26  ? 353 PHE E CB  1 
ATOM   6638 C CG  . PHE D 2 114 ? 206.019 196.520 282.434 1.00 37.38  ? 353 PHE E CG  1 
ATOM   6639 C CD1 . PHE D 2 114 ? 207.015 197.237 281.801 1.00 44.76  ? 353 PHE E CD1 1 
ATOM   6640 C CD2 . PHE D 2 114 ? 205.482 197.019 283.605 1.00 43.16  ? 353 PHE E CD2 1 
ATOM   6641 C CE1 . PHE D 2 114 ? 207.472 198.422 282.326 1.00 49.36  ? 353 PHE E CE1 1 
ATOM   6642 C CE2 . PHE D 2 114 ? 205.935 198.206 284.135 1.00 51.29  ? 353 PHE E CE2 1 
ATOM   6643 C CZ  . PHE D 2 114 ? 206.932 198.908 283.495 1.00 49.94  ? 353 PHE E CZ  1 
ATOM   6644 N N   . ALA D 2 115 ? 205.210 193.854 278.806 1.00 40.22  ? 354 ALA E N   1 
ATOM   6645 C CA  . ALA D 2 115 ? 205.111 192.614 278.055 1.00 41.92  ? 354 ALA E CA  1 
ATOM   6646 C C   . ALA D 2 115 ? 206.422 191.852 277.943 1.00 45.48  ? 354 ALA E C   1 
ATOM   6647 O O   . ALA D 2 115 ? 206.387 190.650 277.657 1.00 52.50  ? 354 ALA E O   1 
ATOM   6648 C CB  . ALA D 2 115 ? 204.576 192.884 276.640 1.00 41.40  ? 354 ALA E CB  1 
ATOM   6649 N N   . SER D 2 116 ? 207.564 192.499 278.159 1.00 39.54  ? 355 SER E N   1 
ATOM   6650 C CA  . SER D 2 116 ? 208.849 191.819 278.089 1.00 43.80  ? 355 SER E CA  1 
ATOM   6651 C C   . SER D 2 116 ? 209.909 192.688 278.749 1.00 48.85  ? 355 SER E C   1 
ATOM   6652 O O   . SER D 2 116 ? 209.706 193.883 278.972 1.00 47.72  ? 355 SER E O   1 
ATOM   6653 C CB  . SER D 2 116 ? 209.234 191.499 276.641 1.00 43.00  ? 355 SER E CB  1 
ATOM   6654 O OG  . SER D 2 116 ? 209.083 192.637 275.812 1.00 46.24  ? 355 SER E OG  1 
ATOM   6655 N N   . GLY D 2 117 ? 211.041 192.066 279.065 1.00 57.83  ? 356 GLY E N   1 
ATOM   6656 C CA  . GLY D 2 117 ? 212.180 192.770 279.615 1.00 58.79  ? 356 GLY E CA  1 
ATOM   6657 C C   . GLY D 2 117 ? 212.114 192.941 281.124 1.00 58.59  ? 356 GLY E C   1 
ATOM   6658 O O   . GLY D 2 117 ? 211.145 192.574 281.792 1.00 58.67  ? 356 GLY E O   1 
ATOM   6659 N N   . LYS D 2 118 ? 213.185 193.519 281.665 1.00 45.23  ? 357 LYS E N   1 
ATOM   6660 C CA  . LYS D 2 118 ? 213.316 193.768 283.094 1.00 40.91  ? 357 LYS E CA  1 
ATOM   6661 C C   . LYS D 2 118 ? 212.925 195.207 283.401 1.00 48.92  ? 357 LYS E C   1 
ATOM   6662 O O   . LYS D 2 118 ? 213.377 196.135 282.723 1.00 53.59  ? 357 LYS E O   1 
ATOM   6663 C CB  . LYS D 2 118 ? 214.746 193.501 283.564 1.00 43.01  ? 357 LYS E CB  1 
ATOM   6664 C CG  . LYS D 2 118 ? 215.491 192.474 282.734 1.00 39.62  ? 357 LYS E CG  1 
ATOM   6665 C CD  . LYS D 2 118 ? 216.995 192.668 282.837 1.00 38.81  ? 357 LYS E CD  1 
ATOM   6666 C CE  . LYS D 2 118 ? 217.558 192.023 284.091 1.00 39.86  ? 357 LYS E CE  1 
ATOM   6667 N NZ  . LYS D 2 118 ? 217.615 190.542 283.975 1.00 47.48  ? 357 LYS E NZ  1 
ATOM   6668 N N   . HIS D 2 119 ? 212.085 195.388 284.419 1.00 49.34  ? 358 HIS E N   1 
ATOM   6669 C CA  . HIS D 2 119 ? 211.582 196.709 284.775 1.00 49.56  ? 358 HIS E CA  1 
ATOM   6670 C C   . HIS D 2 119 ? 211.306 196.766 286.271 1.00 44.61  ? 358 HIS E C   1 
ATOM   6671 O O   . HIS D 2 119 ? 210.810 195.804 286.859 1.00 51.70  ? 358 HIS E O   1 
ATOM   6672 C CB  . HIS D 2 119 ? 210.312 197.052 283.989 1.00 51.77  ? 358 HIS E CB  1 
ATOM   6673 C CG  . HIS D 2 119 ? 210.308 196.520 282.590 1.00 51.16  ? 358 HIS E CG  1 
ATOM   6674 N ND1 . HIS D 2 119 ? 210.968 197.146 281.555 1.00 49.86  ? 358 HIS E ND1 1 
ATOM   6675 C CD2 . HIS D 2 119 ? 209.752 195.405 282.062 1.00 47.68  ? 358 HIS E CD2 1 
ATOM   6676 C CE1 . HIS D 2 119 ? 210.803 196.450 280.445 1.00 50.46  ? 358 HIS E CE1 1 
ATOM   6677 N NE2 . HIS D 2 119 ? 210.069 195.389 280.725 1.00 50.25  ? 358 HIS E NE2 1 
ATOM   6678 N N   . TYR D 2 120 ? 211.616 197.907 286.884 1.00 33.50  ? 359 TYR E N   1 
ATOM   6679 C CA  . TYR D 2 120 ? 211.472 198.022 288.328 1.00 35.79  ? 359 TYR E CA  1 
ATOM   6680 C C   . TYR D 2 120 ? 211.017 199.425 288.703 1.00 41.65  ? 359 TYR E C   1 
ATOM   6681 O O   . TYR D 2 120 ? 211.191 200.383 287.946 1.00 47.84  ? 359 TYR E O   1 
ATOM   6682 C CB  . TYR D 2 120 ? 212.779 197.660 289.046 1.00 39.72  ? 359 TYR E CB  1 
ATOM   6683 C CG  . TYR D 2 120 ? 213.715 198.816 289.306 1.00 45.46  ? 359 TYR E CG  1 
ATOM   6684 C CD1 . TYR D 2 120 ? 214.635 199.215 288.350 1.00 42.47  ? 359 TYR E CD1 1 
ATOM   6685 C CD2 . TYR D 2 120 ? 213.700 199.490 290.518 1.00 46.34  ? 359 TYR E CD2 1 
ATOM   6686 C CE1 . TYR D 2 120 ? 215.502 200.261 288.587 1.00 39.07  ? 359 TYR E CE1 1 
ATOM   6687 C CE2 . TYR D 2 120 ? 214.561 200.537 290.762 1.00 38.18  ? 359 TYR E CE2 1 
ATOM   6688 C CZ  . TYR D 2 120 ? 215.460 200.918 289.794 1.00 37.20  ? 359 TYR E CZ  1 
ATOM   6689 O OH  . TYR D 2 120 ? 216.320 201.961 290.034 1.00 42.84  ? 359 TYR E OH  1 
ATOM   6690 N N   . TRP D 2 121 ? 210.426 199.528 289.892 1.00 34.98  ? 360 TRP E N   1 
ATOM   6691 C CA  . TRP D 2 121 ? 209.946 200.808 290.399 1.00 35.95  ? 360 TRP E CA  1 
ATOM   6692 C C   . TRP D 2 121 ? 210.038 200.825 291.919 1.00 39.17  ? 360 TRP E C   1 
ATOM   6693 O O   . TRP D 2 121 ? 210.267 199.798 292.558 1.00 38.83  ? 360 TRP E O   1 
ATOM   6694 C CB  . TRP D 2 121 ? 208.514 201.103 289.938 1.00 41.24  ? 360 TRP E CB  1 
ATOM   6695 C CG  . TRP D 2 121 ? 207.504 200.074 290.326 1.00 39.24  ? 360 TRP E CG  1 
ATOM   6696 C CD1 . TRP D 2 121 ? 206.712 200.081 291.436 1.00 43.31  ? 360 TRP E CD1 1 
ATOM   6697 C CD2 . TRP D 2 121 ? 207.155 198.896 289.593 1.00 33.71  ? 360 TRP E CD2 1 
ATOM   6698 N NE1 . TRP D 2 121 ? 205.899 198.976 291.445 1.00 39.14  ? 360 TRP E NE1 1 
ATOM   6699 C CE2 . TRP D 2 121 ? 206.152 198.232 290.323 1.00 34.63  ? 360 TRP E CE2 1 
ATOM   6700 C CE3 . TRP D 2 121 ? 207.597 198.336 288.393 1.00 38.06  ? 360 TRP E CE3 1 
ATOM   6701 C CZ2 . TRP D 2 121 ? 205.587 197.037 289.893 1.00 42.04  ? 360 TRP E CZ2 1 
ATOM   6702 C CZ3 . TRP D 2 121 ? 207.033 197.151 287.969 1.00 36.43  ? 360 TRP E CZ3 1 
ATOM   6703 C CH2 . TRP D 2 121 ? 206.040 196.515 288.716 1.00 39.72  ? 360 TRP E CH2 1 
ATOM   6704 N N   . GLU D 2 122 ? 209.875 202.017 292.492 1.00 46.94  ? 361 GLU E N   1 
ATOM   6705 C CA  . GLU D 2 122 ? 210.062 202.233 293.919 1.00 46.13  ? 361 GLU E CA  1 
ATOM   6706 C C   . GLU D 2 122 ? 208.855 202.952 294.506 1.00 46.50  ? 361 GLU E C   1 
ATOM   6707 O O   . GLU D 2 122 ? 208.259 203.821 293.866 1.00 54.10  ? 361 GLU E O   1 
ATOM   6708 C CB  . GLU D 2 122 ? 211.334 203.039 294.190 1.00 49.01  ? 361 GLU E CB  1 
ATOM   6709 C CG  . GLU D 2 122 ? 212.602 202.309 293.802 1.00 47.18  ? 361 GLU E CG  1 
ATOM   6710 C CD  . GLU D 2 122 ? 213.846 203.127 294.056 1.00 52.97  ? 361 GLU E CD  1 
ATOM   6711 O OE1 . GLU D 2 122 ? 213.975 203.684 295.164 1.00 58.62  ? 361 GLU E OE1 1 
ATOM   6712 O OE2 . GLU D 2 122 ? 214.699 203.212 293.148 1.00 59.08  ? 361 GLU E OE2 1 
ATOM   6713 N N   . VAL D 2 123 ? 208.502 202.582 295.737 1.00 45.62  ? 362 VAL E N   1 
ATOM   6714 C CA  . VAL D 2 123 ? 207.307 203.084 296.404 1.00 55.48  ? 362 VAL E CA  1 
ATOM   6715 C C   . VAL D 2 123 ? 207.674 203.563 297.803 1.00 60.33  ? 362 VAL E C   1 
ATOM   6716 O O   . VAL D 2 123 ? 208.443 202.905 298.514 1.00 59.71  ? 362 VAL E O   1 
ATOM   6717 C CB  . VAL D 2 123 ? 206.201 202.007 296.474 1.00 55.12  ? 362 VAL E CB  1 
ATOM   6718 C CG1 . VAL D 2 123 ? 204.940 202.574 297.099 1.00 56.31  ? 362 VAL E CG1 1 
ATOM   6719 C CG2 . VAL D 2 123 ? 205.899 201.455 295.094 1.00 53.88  ? 362 VAL E CG2 1 
ATOM   6720 N N   . GLU D 2 124 ? 207.120 204.714 298.191 1.00 64.11  ? 363 GLU E N   1 
ATOM   6721 C CA  . GLU D 2 124 ? 207.287 205.272 299.531 1.00 59.34  ? 363 GLU E CA  1 
ATOM   6722 C C   . GLU D 2 124 ? 206.075 204.889 300.374 1.00 61.07  ? 363 GLU E C   1 
ATOM   6723 O O   . GLU D 2 124 ? 204.967 205.379 300.135 1.00 59.96  ? 363 GLU E O   1 
ATOM   6724 C CB  . GLU D 2 124 ? 207.436 206.790 299.465 1.00 57.98  ? 363 GLU E CB  1 
ATOM   6725 C CG  . GLU D 2 124 ? 208.730 207.277 298.845 1.00 66.11  ? 363 GLU E CG  1 
ATOM   6726 C CD  . GLU D 2 124 ? 209.774 207.641 299.881 1.00 72.43  ? 363 GLU E CD  1 
ATOM   6727 O OE1 . GLU D 2 124 ? 209.447 207.621 301.086 1.00 74.67  ? 363 GLU E OE1 1 
ATOM   6728 O OE2 . GLU D 2 124 ? 210.920 207.950 299.490 1.00 68.34  ? 363 GLU E OE2 1 
ATOM   6729 N N   . VAL D 2 125 ? 206.280 204.018 301.360 1.00 67.48  ? 364 VAL E N   1 
ATOM   6730 C CA  . VAL D 2 125 ? 205.183 203.547 302.199 1.00 68.44  ? 364 VAL E CA  1 
ATOM   6731 C C   . VAL D 2 125 ? 205.543 203.673 303.674 1.00 77.03  ? 364 VAL E C   1 
ATOM   6732 O O   . VAL D 2 125 ? 205.024 202.930 304.514 1.00 84.25  ? 364 VAL E O   1 
ATOM   6733 C CB  . VAL D 2 125 ? 204.810 202.095 301.854 1.00 76.01  ? 364 VAL E CB  1 
ATOM   6734 C CG1 . VAL D 2 125 ? 203.926 202.058 300.620 1.00 77.13  ? 364 VAL E CG1 1 
ATOM   6735 C CG2 . VAL D 2 125 ? 206.063 201.265 301.646 1.00 74.86  ? 364 VAL E CG2 1 
ATOM   6736 N N   . GLU D 2 126 ? 206.442 204.604 304.000 1.00 78.40  ? 365 GLU E N   1 
ATOM   6737 C CA  . GLU D 2 126 ? 206.880 204.748 305.386 1.00 76.12  ? 365 GLU E CA  1 
ATOM   6738 C C   . GLU D 2 126 ? 205.754 205.263 306.275 1.00 78.47  ? 365 GLU E C   1 
ATOM   6739 O O   . GLU D 2 126 ? 205.708 204.955 307.471 1.00 70.52  ? 365 GLU E O   1 
ATOM   6740 C CB  . GLU D 2 126 ? 208.134 205.639 305.430 1.00 73.98  ? 365 GLU E CB  1 
ATOM   6741 C CG  . GLU D 2 126 ? 208.614 206.240 306.776 1.00 83.15  ? 365 GLU E CG  1 
ATOM   6742 C CD  . GLU D 2 126 ? 207.708 207.292 307.409 1.00 87.01  ? 365 GLU E CD  1 
ATOM   6743 O OE1 . GLU D 2 126 ? 206.752 207.759 306.759 1.00 85.13  ? 365 GLU E OE1 1 
ATOM   6744 O OE2 . GLU D 2 126 ? 207.960 207.653 308.578 1.00 89.37  ? 365 GLU E OE2 1 
ATOM   6745 N N   . ASN D 2 127 ? 204.834 206.040 305.711 1.00 81.30  ? 366 ASN E N   1 
ATOM   6746 C CA  . ASN D 2 127 ? 203.799 206.713 306.485 1.00 76.46  ? 366 ASN E CA  1 
ATOM   6747 C C   . ASN D 2 127 ? 202.560 205.861 306.729 1.00 78.74  ? 366 ASN E C   1 
ATOM   6748 O O   . ASN D 2 127 ? 201.666 206.298 307.461 1.00 77.61  ? 366 ASN E O   1 
ATOM   6749 C CB  . ASN D 2 127 ? 203.394 208.017 305.789 1.00 76.72  ? 366 ASN E CB  1 
ATOM   6750 C CG  . ASN D 2 127 ? 203.446 207.913 304.277 1.00 77.69  ? 366 ASN E CG  1 
ATOM   6751 O OD1 . ASN D 2 127 ? 203.061 206.897 303.701 1.00 80.15  ? 366 ASN E OD1 1 
ATOM   6752 N ND2 . ASN D 2 127 ? 203.923 208.966 303.627 1.00 77.02  ? 366 ASN E ND2 1 
ATOM   6753 N N   . VAL D 2 128 ? 202.478 204.666 306.155 1.00 85.21  ? 367 VAL E N   1 
ATOM   6754 C CA  . VAL D 2 128 ? 201.289 203.835 306.265 1.00 81.01  ? 367 VAL E CA  1 
ATOM   6755 C C   . VAL D 2 128 ? 201.603 202.606 307.112 1.00 83.31  ? 367 VAL E C   1 
ATOM   6756 O O   . VAL D 2 128 ? 202.745 202.361 307.499 1.00 80.41  ? 367 VAL E O   1 
ATOM   6757 C CB  . VAL D 2 128 ? 200.735 203.433 304.887 1.00 82.98  ? 367 VAL E CB  1 
ATOM   6758 C CG1 . VAL D 2 128 ? 199.902 204.556 304.322 1.00 84.57  ? 367 VAL E CG1 1 
ATOM   6759 C CG2 . VAL D 2 128 ? 201.868 203.092 303.943 1.00 81.81  ? 367 VAL E CG2 1 
ATOM   6760 N N   . ILE D 2 129 ? 200.560 201.826 307.397 1.00 86.52  ? 368 ILE E N   1 
ATOM   6761 C CA  . ILE D 2 129 ? 200.669 200.683 308.297 1.00 88.80  ? 368 ILE E CA  1 
ATOM   6762 C C   . ILE D 2 129 ? 200.161 199.419 307.613 1.00 85.97  ? 368 ILE E C   1 
ATOM   6763 O O   . ILE D 2 129 ? 200.462 198.302 308.047 1.00 82.41  ? 368 ILE E O   1 
ATOM   6764 C CB  . ILE D 2 129 ? 199.903 200.946 309.607 1.00 86.62  ? 368 ILE E CB  1 
ATOM   6765 C CG1 . ILE D 2 129 ? 200.423 200.048 310.731 1.00 85.79  ? 368 ILE E CG1 1 
ATOM   6766 C CG2 . ILE D 2 129 ? 198.410 200.745 309.405 1.00 84.74  ? 368 ILE E CG2 1 
ATOM   6767 C CD1 . ILE D 2 129 ? 201.929 199.956 310.795 1.00 85.77  ? 368 ILE E CD1 1 
ATOM   6768 N N   . GLU D 2 130 ? 199.388 199.581 306.543 1.00 84.00  ? 369 GLU E N   1 
ATOM   6769 C CA  . GLU D 2 130 ? 198.772 198.465 305.827 1.00 78.80  ? 369 GLU E CA  1 
ATOM   6770 C C   . GLU D 2 130 ? 198.876 198.742 304.329 1.00 82.93  ? 369 GLU E C   1 
ATOM   6771 O O   . GLU D 2 130 ? 197.986 199.365 303.745 1.00 88.42  ? 369 GLU E O   1 
ATOM   6772 C CB  . GLU D 2 130 ? 197.318 198.291 306.266 1.00 83.57  ? 369 GLU E CB  1 
ATOM   6773 C CG  . GLU D 2 130 ? 196.647 197.013 305.790 1.00 87.47  ? 369 GLU E CG  1 
ATOM   6774 C CD  . GLU D 2 130 ? 196.717 195.898 306.815 1.00 92.44  ? 369 GLU E CD  1 
ATOM   6775 O OE1 . GLU D 2 130 ? 196.816 196.201 308.023 1.00 90.96  ? 369 GLU E OE1 1 
ATOM   6776 O OE2 . GLU D 2 130 ? 196.667 194.717 306.413 1.00 90.75  ? 369 GLU E OE2 1 
ATOM   6777 N N   . TRP D 2 131 ? 199.955 198.278 303.704 1.00 63.34  ? 370 TRP E N   1 
ATOM   6778 C CA  . TRP D 2 131 ? 200.170 198.489 302.279 1.00 56.26  ? 370 TRP E CA  1 
ATOM   6779 C C   . TRP D 2 131 ? 200.403 197.162 301.576 1.00 61.60  ? 370 TRP E C   1 
ATOM   6780 O O   . TRP D 2 131 ? 201.038 196.258 302.125 1.00 67.75  ? 370 TRP E O   1 
ATOM   6781 C CB  . TRP D 2 131 ? 201.355 199.425 302.010 1.00 53.23  ? 370 TRP E CB  1 
ATOM   6782 C CG  . TRP D 2 131 ? 202.545 199.249 302.910 1.00 59.43  ? 370 TRP E CG  1 
ATOM   6783 C CD1 . TRP D 2 131 ? 202.721 199.792 304.147 1.00 67.00  ? 370 TRP E CD1 1 
ATOM   6784 C CD2 . TRP D 2 131 ? 203.742 198.513 302.623 1.00 59.54  ? 370 TRP E CD2 1 
ATOM   6785 N NE1 . TRP D 2 131 ? 203.945 199.430 304.656 1.00 65.88  ? 370 TRP E NE1 1 
ATOM   6786 C CE2 . TRP D 2 131 ? 204.592 198.646 303.738 1.00 58.79  ? 370 TRP E CE2 1 
ATOM   6787 C CE3 . TRP D 2 131 ? 204.175 197.751 301.535 1.00 64.01  ? 370 TRP E CE3 1 
ATOM   6788 C CZ2 . TRP D 2 131 ? 205.846 198.043 303.799 1.00 53.56  ? 370 TRP E CZ2 1 
ATOM   6789 C CZ3 . TRP D 2 131 ? 205.422 197.152 301.598 1.00 64.55  ? 370 TRP E CZ3 1 
ATOM   6790 C CH2 . TRP D 2 131 ? 206.242 197.302 302.721 1.00 55.41  ? 370 TRP E CH2 1 
ATOM   6791 N N   . THR D 2 132 ? 199.885 197.054 300.354 1.00 51.12  ? 371 THR E N   1 
ATOM   6792 C CA  . THR D 2 132 ? 200.111 195.902 299.491 1.00 48.56  ? 371 THR E CA  1 
ATOM   6793 C C   . THR D 2 132 ? 200.657 196.416 298.170 1.00 48.63  ? 371 THR E C   1 
ATOM   6794 O O   . THR D 2 132 ? 200.061 197.307 297.559 1.00 49.75  ? 371 THR E O   1 
ATOM   6795 C CB  . THR D 2 132 ? 198.817 195.115 299.270 1.00 51.58  ? 371 THR E CB  1 
ATOM   6796 O OG1 . THR D 2 132 ? 198.581 194.254 300.389 1.00 60.65  ? 371 THR E OG1 1 
ATOM   6797 C CG2 . THR D 2 132 ? 198.910 194.276 298.008 1.00 55.27  ? 371 THR E CG2 1 
ATOM   6798 N N   . VAL D 2 133 ? 201.791 195.873 297.732 1.00 51.68  ? 372 VAL E N   1 
ATOM   6799 C CA  . VAL D 2 133 ? 202.402 196.322 296.486 1.00 47.04  ? 372 VAL E CA  1 
ATOM   6800 C C   . VAL D 2 133 ? 202.869 195.114 295.689 1.00 50.03  ? 372 VAL E C   1 
ATOM   6801 O O   . VAL D 2 133 ? 203.388 194.142 296.241 1.00 60.08  ? 372 VAL E O   1 
ATOM   6802 C CB  . VAL D 2 133 ? 203.581 197.294 296.728 1.00 48.83  ? 372 VAL E CB  1 
ATOM   6803 C CG1 . VAL D 2 133 ? 203.085 198.603 297.316 1.00 48.31  ? 372 VAL E CG1 1 
ATOM   6804 C CG2 . VAL D 2 133 ? 204.622 196.668 297.639 1.00 44.95  ? 372 VAL E CG2 1 
ATOM   6805 N N   . GLY D 2 134 ? 202.686 195.174 294.373 1.00 24.66  ? 373 GLY E N   1 
ATOM   6806 C CA  . GLY D 2 134 ? 203.254 194.119 293.554 1.00 27.95  ? 373 GLY E CA  1 
ATOM   6807 C C   . GLY D 2 134 ? 202.799 194.205 292.108 1.00 29.29  ? 373 GLY E C   1 
ATOM   6808 O O   . GLY D 2 134 ? 202.549 195.285 291.582 1.00 41.39  ? 373 GLY E O   1 
ATOM   6809 N N   . VAL D 2 135 ? 202.715 193.030 291.491 1.00 41.21  ? 374 VAL E N   1 
ATOM   6810 C CA  . VAL D 2 135 ? 202.419 192.874 290.072 1.00 39.43  ? 374 VAL E CA  1 
ATOM   6811 C C   . VAL D 2 135 ? 201.116 192.101 289.926 1.00 49.79  ? 374 VAL E C   1 
ATOM   6812 O O   . VAL D 2 135 ? 200.799 191.242 290.758 1.00 65.84  ? 374 VAL E O   1 
ATOM   6813 C CB  . VAL D 2 135 ? 203.571 192.149 289.348 1.00 33.38  ? 374 VAL E CB  1 
ATOM   6814 C CG1 . VAL D 2 135 ? 203.310 192.077 287.857 1.00 40.66  ? 374 VAL E CG1 1 
ATOM   6815 C CG2 . VAL D 2 135 ? 204.893 192.836 289.633 1.00 33.65  ? 374 VAL E CG2 1 
ATOM   6816 N N   . CYS D 2 136 ? 200.358 192.403 288.873 1.00 41.27  ? 375 CYS E N   1 
ATOM   6817 C CA  . CYS D 2 136 ? 199.107 191.709 288.620 1.00 42.38  ? 375 CYS E CA  1 
ATOM   6818 C C   . CYS D 2 136 ? 198.947 191.456 287.129 1.00 50.51  ? 375 CYS E C   1 
ATOM   6819 O O   . CYS D 2 136 ? 199.475 192.194 286.294 1.00 59.56  ? 375 CYS E O   1 
ATOM   6820 C CB  . CYS D 2 136 ? 197.909 192.505 289.145 1.00 46.14  ? 375 CYS E CB  1 
ATOM   6821 S SG  . CYS D 2 136 ? 197.128 193.563 287.917 1.00 74.93  ? 375 CYS E SG  1 
ATOM   6822 N N   . ARG D 2 137 ? 198.220 190.392 286.805 1.00 57.56  ? 376 ARG E N   1 
ATOM   6823 C CA  . ARG D 2 137 ? 197.847 190.138 285.423 1.00 58.55  ? 376 ARG E CA  1 
ATOM   6824 C C   . ARG D 2 137 ? 196.757 191.111 284.993 1.00 62.00  ? 376 ARG E C   1 
ATOM   6825 O O   . ARG D 2 137 ? 195.933 191.550 285.799 1.00 68.79  ? 376 ARG E O   1 
ATOM   6826 C CB  . ARG D 2 137 ? 197.360 188.700 285.252 1.00 61.64  ? 376 ARG E CB  1 
ATOM   6827 C CG  . ARG D 2 137 ? 198.469 187.664 285.268 1.00 64.62  ? 376 ARG E CG  1 
ATOM   6828 C CD  . ARG D 2 137 ? 197.949 186.284 284.904 1.00 58.50  ? 376 ARG E CD  1 
ATOM   6829 N NE  . ARG D 2 137 ? 199.001 185.436 284.361 1.00 54.21  ? 376 ARG E NE  1 
ATOM   6830 C CZ  . ARG D 2 137 ? 199.605 184.470 285.039 1.00 56.97  ? 376 ARG E CZ  1 
ATOM   6831 N NH1 . ARG D 2 137 ? 199.281 184.200 286.291 1.00 60.07  ? 376 ARG E NH1 1 
ATOM   6832 N NH2 . ARG D 2 137 ? 200.558 183.759 284.445 1.00 57.51  ? 376 ARG E NH2 1 
ATOM   6833 N N   . ASP D 2 138 ? 196.754 191.446 283.703 1.00 64.18  ? 377 ASP E N   1 
ATOM   6834 C CA  . ASP D 2 138 ? 195.791 192.418 283.204 1.00 66.42  ? 377 ASP E CA  1 
ATOM   6835 C C   . ASP D 2 138 ? 194.358 191.903 283.250 1.00 76.57  ? 377 ASP E C   1 
ATOM   6836 O O   . ASP D 2 138 ? 193.425 192.696 283.090 1.00 78.26  ? 377 ASP E O   1 
ATOM   6837 C CB  . ASP D 2 138 ? 196.145 192.825 281.776 1.00 65.52  ? 377 ASP E CB  1 
ATOM   6838 C CG  . ASP D 2 138 ? 195.880 194.288 281.508 1.00 69.53  ? 377 ASP E CG  1 
ATOM   6839 O OD1 . ASP D 2 138 ? 195.523 195.009 282.462 1.00 72.65  ? 377 ASP E OD1 1 
ATOM   6840 O OD2 . ASP D 2 138 ? 196.027 194.718 280.346 1.00 72.82  ? 377 ASP E OD2 1 
ATOM   6841 N N   . SER D 2 139 ? 194.161 190.603 283.468 1.00 81.26  ? 378 SER E N   1 
ATOM   6842 C CA  . SER D 2 139 ? 192.838 189.993 283.442 1.00 77.66  ? 378 SER E CA  1 
ATOM   6843 C C   . SER D 2 139 ? 192.361 189.581 284.832 1.00 77.37  ? 378 SER E C   1 
ATOM   6844 O O   . SER D 2 139 ? 191.645 188.588 284.976 1.00 79.97  ? 378 SER E O   1 
ATOM   6845 C CB  . SER D 2 139 ? 192.827 188.787 282.504 1.00 77.61  ? 378 SER E CB  1 
ATOM   6846 O OG  . SER D 2 139 ? 193.964 187.969 282.716 1.00 79.28  ? 378 SER E OG  1 
ATOM   6847 N N   . VAL D 2 140 ? 192.749 190.329 285.865 1.00 72.30  ? 379 VAL E N   1 
ATOM   6848 C CA  . VAL D 2 140 ? 192.263 190.032 287.205 1.00 73.39  ? 379 VAL E CA  1 
ATOM   6849 C C   . VAL D 2 140 ? 190.817 190.497 287.342 1.00 75.15  ? 379 VAL E C   1 
ATOM   6850 O O   . VAL D 2 140 ? 190.412 191.525 286.782 1.00 76.47  ? 379 VAL E O   1 
ATOM   6851 C CB  . VAL D 2 140 ? 193.158 190.682 288.276 1.00 66.06  ? 379 VAL E CB  1 
ATOM   6852 C CG1 . VAL D 2 140 ? 194.519 190.015 288.295 1.00 70.50  ? 379 VAL E CG1 1 
ATOM   6853 C CG2 . VAL D 2 140 ? 193.292 192.172 288.024 1.00 66.67  ? 379 VAL E CG2 1 
ATOM   6854 N N   . GLU D 2 141 ? 190.026 189.723 288.078 1.00 87.21  ? 380 GLU E N   1 
ATOM   6855 C CA  . GLU D 2 141 ? 188.642 190.096 288.329 1.00 86.39  ? 380 GLU E CA  1 
ATOM   6856 C C   . GLU D 2 141 ? 188.584 191.391 289.129 1.00 84.89  ? 380 GLU E C   1 
ATOM   6857 O O   . GLU D 2 141 ? 189.418 191.650 290.001 1.00 83.98  ? 380 GLU E O   1 
ATOM   6858 C CB  . GLU D 2 141 ? 187.910 188.980 289.074 1.00 93.47  ? 380 GLU E CB  1 
ATOM   6859 C CG  . GLU D 2 141 ? 186.441 188.835 288.700 1.00 94.46  ? 380 GLU E CG  1 
ATOM   6860 C CD  . GLU D 2 141 ? 185.581 189.962 289.238 1.00 92.61  ? 380 GLU E CD  1 
ATOM   6861 O OE1 . GLU D 2 141 ? 184.678 190.422 288.510 1.00 89.72  ? 380 GLU E OE1 1 
ATOM   6862 O OE2 . GLU D 2 141 ? 185.811 190.392 290.388 1.00 94.02  ? 380 GLU E OE2 1 
ATOM   6863 N N   . ARG D 2 142 ? 187.588 192.209 288.823 1.00 76.32  ? 381 ARG E N   1 
ATOM   6864 C CA  . ARG D 2 142 ? 187.495 193.553 289.372 1.00 77.72  ? 381 ARG E CA  1 
ATOM   6865 C C   . ARG D 2 142 ? 186.219 193.795 290.159 1.00 77.54  ? 381 ARG E C   1 
ATOM   6866 O O   . ARG D 2 142 ? 186.251 194.498 291.171 1.00 79.34  ? 381 ARG E O   1 
ATOM   6867 C CB  . ARG D 2 142 ? 187.600 194.573 288.228 1.00 85.30  ? 381 ARG E CB  1 
ATOM   6868 C CG  . ARG D 2 142 ? 188.720 194.244 287.249 1.00 85.63  ? 381 ARG E CG  1 
ATOM   6869 C CD  . ARG D 2 142 ? 190.043 194.873 287.658 1.00 81.82  ? 381 ARG E CD  1 
ATOM   6870 N NE  . ARG D 2 142 ? 191.078 194.757 286.635 1.00 76.91  ? 381 ARG E NE  1 
ATOM   6871 C CZ  . ARG D 2 142 ? 191.009 195.258 285.409 1.00 74.21  ? 381 ARG E CZ  1 
ATOM   6872 N NH1 . ARG D 2 142 ? 189.966 195.959 285.001 1.00 73.37  ? 381 ARG E NH1 1 
ATOM   6873 N NH2 . ARG D 2 142 ? 192.021 195.056 284.570 1.00 77.64  ? 381 ARG E NH2 1 
ATOM   6874 N N   . LYS D 2 143 ? 185.094 193.226 289.719 1.00 86.81  ? 382 LYS E N   1 
ATOM   6875 C CA  . LYS D 2 143 ? 183.814 193.487 290.371 1.00 90.05  ? 382 LYS E CA  1 
ATOM   6876 C C   . LYS D 2 143 ? 183.798 192.958 291.801 1.00 91.29  ? 382 LYS E C   1 
ATOM   6877 O O   . LYS D 2 143 ? 183.498 193.703 292.741 1.00 90.39  ? 382 LYS E O   1 
ATOM   6878 C CB  . LYS D 2 143 ? 182.686 192.858 289.543 1.00 91.07  ? 382 LYS E CB  1 
ATOM   6879 C CG  . LYS D 2 143 ? 181.219 192.870 290.073 1.00 91.78  ? 382 LYS E CG  1 
ATOM   6880 C CD  . LYS D 2 143 ? 180.784 193.911 291.128 1.00 95.00  ? 382 LYS E CD  1 
ATOM   6881 C CE  . LYS D 2 143 ? 181.117 195.357 290.771 1.00 94.14  ? 382 LYS E CE  1 
ATOM   6882 N NZ  . LYS D 2 143 ? 180.954 196.258 291.945 1.00 94.68  ? 382 LYS E NZ  1 
ATOM   6883 N N   . GLY D 2 144 ? 184.136 191.680 291.990 1.00 92.31  ? 383 GLY E N   1 
ATOM   6884 C CA  . GLY D 2 144 ? 184.018 191.030 293.274 1.00 90.60  ? 383 GLY E CA  1 
ATOM   6885 C C   . GLY D 2 144 ? 185.361 190.899 293.977 1.00 89.23  ? 383 GLY E C   1 
ATOM   6886 O O   . GLY D 2 144 ? 186.430 191.007 293.366 1.00 92.12  ? 383 GLY E O   1 
ATOM   6887 N N   . GLU D 2 145 ? 185.285 190.672 295.286 1.00 83.56  ? 384 GLU E N   1 
ATOM   6888 C CA  . GLU D 2 145 ? 186.485 190.468 296.086 1.00 83.59  ? 384 GLU E CA  1 
ATOM   6889 C C   . GLU D 2 145 ? 187.225 189.226 295.614 1.00 84.62  ? 384 GLU E C   1 
ATOM   6890 O O   . GLU D 2 145 ? 186.617 188.174 295.396 1.00 86.34  ? 384 GLU E O   1 
ATOM   6891 C CB  . GLU D 2 145 ? 186.116 190.342 297.563 1.00 85.24  ? 384 GLU E CB  1 
ATOM   6892 C CG  . GLU D 2 145 ? 186.108 191.659 298.316 1.00 88.61  ? 384 GLU E CG  1 
ATOM   6893 C CD  . GLU D 2 145 ? 187.465 192.004 298.893 1.00 91.20  ? 384 GLU E CD  1 
ATOM   6894 O OE1 . GLU D 2 145 ? 188.401 191.191 298.738 1.00 91.73  ? 384 GLU E OE1 1 
ATOM   6895 O OE2 . GLU D 2 145 ? 187.599 193.088 299.499 1.00 90.01  ? 384 GLU E OE2 1 
ATOM   6896 N N   . VAL D 2 146 ? 188.540 189.350 295.455 1.00 75.87  ? 385 VAL E N   1 
ATOM   6897 C CA  . VAL D 2 146 ? 189.366 188.248 294.979 1.00 75.49  ? 385 VAL E CA  1 
ATOM   6898 C C   . VAL D 2 146 ? 190.441 187.950 296.011 1.00 73.71  ? 385 VAL E C   1 
ATOM   6899 O O   . VAL D 2 146 ? 190.510 188.600 297.060 1.00 73.90  ? 385 VAL E O   1 
ATOM   6900 C CB  . VAL D 2 146 ? 189.993 188.565 293.610 1.00 74.08  ? 385 VAL E CB  1 
ATOM   6901 C CG1 . VAL D 2 146 ? 188.915 188.925 292.604 1.00 75.22  ? 385 VAL E CG1 1 
ATOM   6902 C CG2 . VAL D 2 146 ? 190.997 189.694 293.745 1.00 73.36  ? 385 VAL E CG2 1 
ATOM   6903 N N   . LEU D 2 147 ? 191.284 186.965 295.722 1.00 74.57  ? 386 LEU E N   1 
ATOM   6904 C CA  . LEU D 2 147 ? 192.374 186.575 296.602 1.00 77.89  ? 386 LEU E CA  1 
ATOM   6905 C C   . LEU D 2 147 ? 193.693 186.992 295.969 1.00 78.85  ? 386 LEU E C   1 
ATOM   6906 O O   . LEU D 2 147 ? 194.013 186.569 294.854 1.00 76.92  ? 386 LEU E O   1 
ATOM   6907 C CB  . LEU D 2 147 ? 192.367 185.067 296.874 1.00 77.09  ? 386 LEU E CB  1 
ATOM   6908 C CG  . LEU D 2 147 ? 191.214 184.392 297.636 1.00 80.43  ? 386 LEU E CG  1 
ATOM   6909 C CD1 . LEU D 2 147 ? 191.165 184.882 299.080 1.00 79.28  ? 386 LEU E CD1 1 
ATOM   6910 C CD2 . LEU D 2 147 ? 189.848 184.526 296.960 1.00 77.77  ? 386 LEU E CD2 1 
ATOM   6911 N N   . LEU D 2 148 ? 194.455 187.818 296.685 1.00 82.49  ? 387 LEU E N   1 
ATOM   6912 C CA  . LEU D 2 148 ? 195.708 188.370 296.173 1.00 79.20  ? 387 LEU E CA  1 
ATOM   6913 C C   . LEU D 2 148 ? 196.788 187.297 296.263 1.00 79.27  ? 387 LEU E C   1 
ATOM   6914 O O   . LEU D 2 148 ? 197.679 187.329 297.115 1.00 83.17  ? 387 LEU E O   1 
ATOM   6915 C CB  . LEU D 2 148 ? 196.098 189.627 296.942 1.00 75.45  ? 387 LEU E CB  1 
ATOM   6916 C CG  . LEU D 2 148 ? 194.991 190.620 297.305 1.00 74.48  ? 387 LEU E CG  1 
ATOM   6917 C CD1 . LEU D 2 148 ? 194.388 190.309 298.667 1.00 73.75  ? 387 LEU E CD1 1 
ATOM   6918 C CD2 . LEU D 2 148 ? 195.523 192.042 297.270 1.00 76.97  ? 387 LEU E CD2 1 
ATOM   6919 N N   . ILE D 2 149 ? 196.707 186.331 295.355 1.00 62.35  ? 388 ILE E N   1 
ATOM   6920 C CA  . ILE D 2 149 ? 197.649 185.214 295.331 1.00 61.59  ? 388 ILE E CA  1 
ATOM   6921 C C   . ILE D 2 149 ? 198.093 184.992 293.892 1.00 67.51  ? 388 ILE E C   1 
ATOM   6922 O O   . ILE D 2 149 ? 197.412 185.416 292.944 1.00 68.66  ? 388 ILE E O   1 
ATOM   6923 C CB  . ILE D 2 149 ? 197.024 183.928 295.921 1.00 67.68  ? 388 ILE E CB  1 
ATOM   6924 C CG1 . ILE D 2 149 ? 195.565 183.791 295.482 1.00 67.88  ? 388 ILE E CG1 1 
ATOM   6925 C CG2 . ILE D 2 149 ? 197.133 183.932 297.437 1.00 66.28  ? 388 ILE E CG2 1 
ATOM   6926 C CD1 . ILE D 2 149 ? 194.850 182.619 296.116 1.00 69.97  ? 388 ILE E CD1 1 
ATOM   6927 N N   . PRO D 2 150 ? 199.241 184.338 293.692 1.00 67.04  ? 389 PRO E N   1 
ATOM   6928 C CA  . PRO D 2 150 ? 199.641 183.979 292.320 1.00 61.72  ? 389 PRO E CA  1 
ATOM   6929 C C   . PRO D 2 150 ? 198.629 183.099 291.620 1.00 65.29  ? 389 PRO E C   1 
ATOM   6930 O O   . PRO D 2 150 ? 198.574 183.106 290.384 1.00 68.95  ? 389 PRO E O   1 
ATOM   6931 C CB  . PRO D 2 150 ? 200.981 183.250 292.499 1.00 57.64  ? 389 PRO E CB  1 
ATOM   6932 C CG  . PRO D 2 150 ? 201.282 183.239 293.944 1.00 67.36  ? 389 PRO E CG  1 
ATOM   6933 C CD  . PRO D 2 150 ? 200.275 184.036 294.694 1.00 66.23  ? 389 PRO E CD  1 
ATOM   6934 N N   . GLN D 2 151 ? 197.831 182.337 292.371 1.00 72.02  ? 390 GLN E N   1 
ATOM   6935 C CA  . GLN D 2 151 ? 196.779 181.534 291.759 1.00 66.44  ? 390 GLN E CA  1 
ATOM   6936 C C   . GLN D 2 151 ? 195.801 182.410 290.992 1.00 67.06  ? 390 GLN E C   1 
ATOM   6937 O O   . GLN D 2 151 ? 195.335 182.035 289.910 1.00 70.49  ? 390 GLN E O   1 
ATOM   6938 C CB  . GLN D 2 151 ? 196.051 180.724 292.833 1.00 60.60  ? 390 GLN E CB  1 
ATOM   6939 C CG  . GLN D 2 151 ? 194.975 179.720 292.368 1.00 64.98  ? 390 GLN E CG  1 
ATOM   6940 C CD  . GLN D 2 151 ? 195.137 179.163 290.951 1.00 73.28  ? 390 GLN E CD  1 
ATOM   6941 O OE1 . GLN D 2 151 ? 196.244 179.023 290.428 1.00 74.66  ? 390 GLN E OE1 1 
ATOM   6942 N NE2 . GLN D 2 151 ? 194.011 178.845 290.325 1.00 74.95  ? 390 GLN E NE2 1 
ATOM   6943 N N   . ASN D 2 152 ? 195.480 183.583 291.532 1.00 62.83  ? 391 ASN E N   1 
ATOM   6944 C CA  . ASN D 2 152 ? 194.571 184.507 290.871 1.00 68.67  ? 391 ASN E CA  1 
ATOM   6945 C C   . ASN D 2 152 ? 195.288 185.534 290.005 1.00 70.10  ? 391 ASN E C   1 
ATOM   6946 O O   . ASN D 2 152 ? 194.620 186.357 289.370 1.00 73.00  ? 391 ASN E O   1 
ATOM   6947 C CB  . ASN D 2 152 ? 193.707 185.230 291.907 1.00 69.81  ? 391 ASN E CB  1 
ATOM   6948 C CG  . ASN D 2 152 ? 192.278 185.413 291.444 1.00 69.11  ? 391 ASN E CG  1 
ATOM   6949 O OD1 . ASN D 2 152 ? 191.586 184.445 291.137 1.00 70.71  ? 391 ASN E OD1 1 
ATOM   6950 N ND2 . ASN D 2 152 ? 191.829 186.660 291.385 1.00 66.16  ? 391 ASN E ND2 1 
ATOM   6951 N N   . GLY D 2 153 ? 196.616 185.510 289.960 1.00 65.27  ? 392 GLY E N   1 
ATOM   6952 C CA  . GLY D 2 153 ? 197.354 186.454 289.145 1.00 65.07  ? 392 GLY E CA  1 
ATOM   6953 C C   . GLY D 2 153 ? 197.842 187.664 289.914 1.00 70.84  ? 392 GLY E C   1 
ATOM   6954 O O   . GLY D 2 153 ? 197.765 188.793 289.421 1.00 75.80  ? 392 GLY E O   1 
ATOM   6955 N N   . PHE D 2 154 ? 198.345 187.443 291.127 1.00 69.33  ? 393 PHE E N   1 
ATOM   6956 C CA  . PHE D 2 154 ? 198.848 188.517 291.978 1.00 58.60  ? 393 PHE E CA  1 
ATOM   6957 C C   . PHE D 2 154 ? 200.177 188.084 292.573 1.00 59.87  ? 393 PHE E C   1 
ATOM   6958 O O   . PHE D 2 154 ? 200.296 186.963 293.072 1.00 72.55  ? 393 PHE E O   1 
ATOM   6959 C CB  . PHE D 2 154 ? 197.853 188.846 293.094 1.00 59.87  ? 393 PHE E CB  1 
ATOM   6960 C CG  . PHE D 2 154 ? 196.645 189.602 292.631 1.00 59.92  ? 393 PHE E CG  1 
ATOM   6961 C CD1 . PHE D 2 154 ? 196.767 190.865 292.083 1.00 66.96  ? 393 PHE E CD1 1 
ATOM   6962 C CD2 . PHE D 2 154 ? 195.384 189.049 292.745 1.00 58.14  ? 393 PHE E CD2 1 
ATOM   6963 C CE1 . PHE D 2 154 ? 195.652 191.561 291.661 1.00 69.21  ? 393 PHE E CE1 1 
ATOM   6964 C CE2 . PHE D 2 154 ? 194.268 189.739 292.324 1.00 62.33  ? 393 PHE E CE2 1 
ATOM   6965 C CZ  . PHE D 2 154 ? 194.402 190.997 291.781 1.00 66.35  ? 393 PHE E CZ  1 
ATOM   6966 N N   . TRP D 2 155 ? 201.168 188.966 292.534 1.00 45.18  ? 394 TRP E N   1 
ATOM   6967 C CA  . TRP D 2 155 ? 202.451 188.746 293.195 1.00 48.34  ? 394 TRP E CA  1 
ATOM   6968 C C   . TRP D 2 155 ? 202.707 189.980 294.053 1.00 52.35  ? 394 TRP E C   1 
ATOM   6969 O O   . TRP D 2 155 ? 203.116 191.023 293.536 1.00 62.27  ? 394 TRP E O   1 
ATOM   6970 C CB  . TRP D 2 155 ? 203.567 188.528 292.179 1.00 47.25  ? 394 TRP E CB  1 
ATOM   6971 C CG  . TRP D 2 155 ? 203.382 187.334 291.291 1.00 51.15  ? 394 TRP E CG  1 
ATOM   6972 C CD1 . TRP D 2 155 ? 204.027 186.137 291.386 1.00 62.28  ? 394 TRP E CD1 1 
ATOM   6973 C CD2 . TRP D 2 155 ? 202.516 187.230 290.155 1.00 50.23  ? 394 TRP E CD2 1 
ATOM   6974 N NE1 . TRP D 2 155 ? 203.610 185.291 290.391 1.00 61.60  ? 394 TRP E NE1 1 
ATOM   6975 C CE2 . TRP D 2 155 ? 202.683 185.939 289.620 1.00 52.36  ? 394 TRP E CE2 1 
ATOM   6976 C CE3 . TRP D 2 155 ? 201.614 188.102 289.540 1.00 54.74  ? 394 TRP E CE3 1 
ATOM   6977 C CZ2 . TRP D 2 155 ? 201.980 185.498 288.504 1.00 50.74  ? 394 TRP E CZ2 1 
ATOM   6978 C CZ3 . TRP D 2 155 ? 200.919 187.662 288.433 1.00 57.16  ? 394 TRP E CZ3 1 
ATOM   6979 C CH2 . TRP D 2 155 ? 201.105 186.373 287.927 1.00 53.96  ? 394 TRP E CH2 1 
ATOM   6980 N N   . THR D 2 156 ? 202.452 189.872 295.357 1.00 47.27  ? 395 THR E N   1 
ATOM   6981 C CA  . THR D 2 156 ? 202.389 191.044 296.218 1.00 45.70  ? 395 THR E CA  1 
ATOM   6982 C C   . THR D 2 156 ? 203.140 190.829 297.524 1.00 45.60  ? 395 THR E C   1 
ATOM   6983 O O   . THR D 2 156 ? 203.286 189.704 298.007 1.00 57.49  ? 395 THR E O   1 
ATOM   6984 C CB  . THR D 2 156 ? 200.936 191.424 296.544 1.00 45.98  ? 395 THR E CB  1 
ATOM   6985 O OG1 . THR D 2 156 ? 200.266 190.300 297.126 1.00 57.29  ? 395 THR E OG1 1 
ATOM   6986 C CG2 . THR D 2 156 ? 200.198 191.852 295.292 1.00 50.12  ? 395 THR E CG2 1 
ATOM   6987 N N   . LEU D 2 157 ? 203.610 191.940 298.084 1.00 37.85  ? 396 LEU E N   1 
ATOM   6988 C CA  . LEU D 2 157 ? 204.143 192.017 299.436 1.00 38.03  ? 396 LEU E CA  1 
ATOM   6989 C C   . LEU D 2 157 ? 203.192 192.870 300.264 1.00 41.84  ? 396 LEU E C   1 
ATOM   6990 O O   . LEU D 2 157 ? 202.669 193.881 299.776 1.00 52.23  ? 396 LEU E O   1 
ATOM   6991 C CB  . LEU D 2 157 ? 205.557 192.614 299.440 1.00 49.88  ? 396 LEU E CB  1 
ATOM   6992 C CG  . LEU D 2 157 ? 206.592 192.206 300.498 1.00 45.59  ? 396 LEU E CG  1 
ATOM   6993 C CD1 . LEU D 2 157 ? 207.896 192.947 300.269 1.00 44.44  ? 396 LEU E CD1 1 
ATOM   6994 C CD2 . LEU D 2 157 ? 206.110 192.474 301.909 1.00 49.31  ? 396 LEU E CD2 1 
ATOM   6995 N N   . GLU D 2 158 ? 202.969 192.460 301.514 1.00 53.33  ? 397 GLU E N   1 
ATOM   6996 C CA  . GLU D 2 158 ? 201.875 192.984 302.315 1.00 53.45  ? 397 GLU E CA  1 
ATOM   6997 C C   . GLU D 2 158 ? 202.358 193.425 303.688 1.00 56.76  ? 397 GLU E C   1 
ATOM   6998 O O   . GLU D 2 158 ? 203.340 192.897 304.214 1.00 55.39  ? 397 GLU E O   1 
ATOM   6999 C CB  . GLU D 2 158 ? 200.778 191.925 302.475 1.00 56.71  ? 397 GLU E CB  1 
ATOM   7000 C CG  . GLU D 2 158 ? 199.422 192.469 302.859 1.00 63.44  ? 397 GLU E CG  1 
ATOM   7001 C CD  . GLU D 2 158 ? 198.296 191.596 302.359 1.00 64.17  ? 397 GLU E CD  1 
ATOM   7002 O OE1 . GLU D 2 158 ? 198.581 190.632 301.620 1.00 61.00  ? 397 GLU E OE1 1 
ATOM   7003 O OE2 . GLU D 2 158 ? 197.129 191.871 302.704 1.00 65.68  ? 397 GLU E OE2 1 
ATOM   7004 N N   . MET D 2 159 ? 201.663 194.407 304.251 1.00 76.56  ? 398 MET E N   1 
ATOM   7005 C CA  . MET D 2 159 ? 201.762 194.769 305.660 1.00 80.66  ? 398 MET E CA  1 
ATOM   7006 C C   . MET D 2 159 ? 200.414 194.521 306.321 1.00 84.39  ? 398 MET E C   1 
ATOM   7007 O O   . MET D 2 159 ? 199.396 195.061 305.876 1.00 82.51  ? 398 MET E O   1 
ATOM   7008 C CB  . MET D 2 159 ? 202.184 196.228 305.830 1.00 79.82  ? 398 MET E CB  1 
ATOM   7009 C CG  . MET D 2 159 ? 203.652 196.409 306.126 1.00 75.40  ? 398 MET E CG  1 
ATOM   7010 S SD  . MET D 2 159 ? 203.994 195.951 307.835 1.00 75.22  ? 398 MET E SD  1 
ATOM   7011 C CE  . MET D 2 159 ? 203.533 197.454 308.684 1.00 75.46  ? 398 MET E CE  1 
ATOM   7012 N N   . HIS D 2 160 ? 200.410 193.710 307.377 1.00 80.53  ? 399 HIS E N   1 
ATOM   7013 C CA  . HIS D 2 160 ? 199.190 193.342 308.080 1.00 75.20  ? 399 HIS E CA  1 
ATOM   7014 C C   . HIS D 2 160 ? 199.464 193.309 309.575 1.00 73.19  ? 399 HIS E C   1 
ATOM   7015 O O   . HIS D 2 160 ? 200.333 192.560 310.031 1.00 73.44  ? 399 HIS E O   1 
ATOM   7016 C CB  . HIS D 2 160 ? 198.670 191.982 307.604 1.00 70.23  ? 399 HIS E CB  1 
ATOM   7017 C CG  . HIS D 2 160 ? 197.290 191.663 308.082 1.00 74.52  ? 399 HIS E CG  1 
ATOM   7018 N ND1 . HIS D 2 160 ? 196.849 190.372 308.277 1.00 77.89  ? 399 HIS E ND1 1 
ATOM   7019 C CD2 . HIS D 2 160 ? 196.250 192.468 308.406 1.00 75.77  ? 399 HIS E CD2 1 
ATOM   7020 C CE1 . HIS D 2 160 ? 195.598 190.395 308.699 1.00 78.05  ? 399 HIS E CE1 1 
ATOM   7021 N NE2 . HIS D 2 160 ? 195.211 191.655 308.786 1.00 78.93  ? 399 HIS E NE2 1 
ATOM   7022 N N   . LYS D 2 161 ? 198.722 194.126 310.326 1.00 81.87  ? 400 LYS E N   1 
ATOM   7023 C CA  . LYS D 2 161 ? 198.823 194.179 311.785 1.00 84.57  ? 400 LYS E CA  1 
ATOM   7024 C C   . LYS D 2 161 ? 200.264 194.397 312.241 1.00 90.21  ? 400 LYS E C   1 
ATOM   7025 O O   . LYS D 2 161 ? 200.742 193.769 313.188 1.00 88.63  ? 400 LYS E O   1 
ATOM   7026 C CB  . LYS D 2 161 ? 198.236 192.918 312.422 1.00 83.18  ? 400 LYS E CB  1 
ATOM   7027 C CG  . LYS D 2 161 ? 196.923 192.468 311.808 1.00 83.91  ? 400 LYS E CG  1 
ATOM   7028 C CD  . LYS D 2 161 ? 196.460 191.146 312.399 1.00 88.42  ? 400 LYS E CD  1 
ATOM   7029 C CE  . LYS D 2 161 ? 197.579 190.117 312.410 1.00 89.77  ? 400 LYS E CE  1 
ATOM   7030 N NZ  . LYS D 2 161 ? 198.124 189.871 311.046 1.00 89.94  ? 400 LYS E NZ  1 
ATOM   7031 N N   . GLY D 2 162 ? 200.964 195.298 311.557 1.00 89.90  ? 401 GLY E N   1 
ATOM   7032 C CA  . GLY D 2 162 ? 202.342 195.577 311.907 1.00 87.37  ? 401 GLY E CA  1 
ATOM   7033 C C   . GLY D 2 162 ? 203.309 194.458 311.606 1.00 83.37  ? 401 GLY E C   1 
ATOM   7034 O O   . GLY D 2 162 ? 204.372 194.385 312.229 1.00 78.12  ? 401 GLY E O   1 
ATOM   7035 N N   . GLN D 2 163 ? 202.971 193.576 310.671 1.00 72.40  ? 402 GLN E N   1 
ATOM   7036 C CA  . GLN D 2 163 ? 203.828 192.459 310.307 1.00 72.76  ? 402 GLN E CA  1 
ATOM   7037 C C   . GLN D 2 163 ? 203.937 192.367 308.793 1.00 75.54  ? 402 GLN E C   1 
ATOM   7038 O O   . GLN D 2 163 ? 202.936 192.481 308.080 1.00 76.35  ? 402 GLN E O   1 
ATOM   7039 C CB  . GLN D 2 163 ? 203.289 191.144 310.877 1.00 76.41  ? 402 GLN E CB  1 
ATOM   7040 C CG  . GLN D 2 163 ? 204.231 189.963 310.725 1.00 72.75  ? 402 GLN E CG  1 
ATOM   7041 C CD  . GLN D 2 163 ? 205.693 190.361 310.768 1.00 71.50  ? 402 GLN E CD  1 
ATOM   7042 O OE1 . GLN D 2 163 ? 206.330 190.544 309.731 1.00 68.40  ? 402 GLN E OE1 1 
ATOM   7043 N NE2 . GLN D 2 163 ? 206.234 190.488 311.972 1.00 73.11  ? 402 GLN E NE2 1 
ATOM   7044 N N   . TYR D 2 164 ? 205.160 192.173 308.309 1.00 76.69  ? 403 TYR E N   1 
ATOM   7045 C CA  . TYR D 2 164 ? 205.391 191.954 306.889 1.00 76.85  ? 403 TYR E CA  1 
ATOM   7046 C C   . TYR D 2 164 ? 204.881 190.578 306.490 1.00 75.63  ? 403 TYR E C   1 
ATOM   7047 O O   . TYR D 2 164 ? 204.891 189.641 307.293 1.00 80.41  ? 403 TYR E O   1 
ATOM   7048 C CB  . TYR D 2 164 ? 206.880 192.083 306.571 1.00 75.88  ? 403 TYR E CB  1 
ATOM   7049 C CG  . TYR D 2 164 ? 207.411 193.473 306.807 1.00 73.16  ? 403 TYR E CG  1 
ATOM   7050 C CD1 . TYR D 2 164 ? 206.657 194.585 306.478 1.00 69.06  ? 403 TYR E CD1 1 
ATOM   7051 C CD2 . TYR D 2 164 ? 208.671 193.674 307.338 1.00 69.68  ? 403 TYR E CD2 1 
ATOM   7052 C CE1 . TYR D 2 164 ? 207.131 195.858 306.691 1.00 71.34  ? 403 TYR E CE1 1 
ATOM   7053 C CE2 . TYR D 2 164 ? 209.155 194.945 307.557 1.00 76.43  ? 403 TYR E CE2 1 
ATOM   7054 C CZ  . TYR D 2 164 ? 208.380 196.033 307.228 1.00 77.44  ? 403 TYR E CZ  1 
ATOM   7055 O OH  . TYR D 2 164 ? 208.854 197.304 307.439 1.00 80.50  ? 403 TYR E OH  1 
ATOM   7056 N N   . ARG D 2 165 ? 204.430 190.459 305.246 1.00 69.48  ? 404 ARG E N   1 
ATOM   7057 C CA  . ARG D 2 165 ? 203.840 189.223 304.767 1.00 62.20  ? 404 ARG E CA  1 
ATOM   7058 C C   . ARG D 2 165 ? 204.095 189.035 303.279 1.00 66.98  ? 404 ARG E C   1 
ATOM   7059 O O   . ARG D 2 165 ? 204.227 189.991 302.508 1.00 83.58  ? 404 ARG E O   1 
ATOM   7060 C CB  . ARG D 2 165 ? 202.330 189.175 305.029 1.00 66.64  ? 404 ARG E CB  1 
ATOM   7061 C CG  . ARG D 2 165 ? 201.954 188.556 306.357 1.00 72.50  ? 404 ARG E CG  1 
ATOM   7062 C CD  . ARG D 2 165 ? 200.691 187.729 306.232 1.00 72.56  ? 404 ARG E CD  1 
ATOM   7063 N NE  . ARG D 2 165 ? 199.493 188.558 306.236 1.00 72.86  ? 404 ARG E NE  1 
ATOM   7064 C CZ  . ARG D 2 165 ? 198.405 188.301 305.525 1.00 73.38  ? 404 ARG E CZ  1 
ATOM   7065 N NH1 . ARG D 2 165 ? 198.326 187.235 304.746 1.00 65.97  ? 404 ARG E NH1 1 
ATOM   7066 N NH2 . ARG D 2 165 ? 197.370 189.132 305.599 1.00 75.05  ? 404 ARG E NH2 1 
ATOM   7067 N N   . ALA D 2 166 ? 204.090 187.764 302.899 1.00 69.93  ? 405 ALA E N   1 
ATOM   7068 C CA  . ALA D 2 166 ? 204.280 187.265 301.547 1.00 71.92  ? 405 ALA E CA  1 
ATOM   7069 C C   . ALA D 2 166 ? 203.012 187.423 300.724 1.00 69.50  ? 405 ALA E C   1 
ATOM   7070 O O   . ALA D 2 166 ? 202.174 188.285 301.007 1.00 76.24  ? 405 ALA E O   1 
ATOM   7071 C CB  . ALA D 2 166 ? 204.700 185.798 301.580 1.00 78.26  ? 405 ALA E CB  1 
ATOM   7072 N N   . VAL D 2 167 ? 202.871 186.584 299.701 1.00 58.05  ? 406 VAL E N   1 
ATOM   7073 C CA  . VAL D 2 167 ? 201.756 186.582 298.758 1.00 63.31  ? 406 VAL E CA  1 
ATOM   7074 C C   . VAL D 2 167 ? 200.423 186.381 299.476 1.00 71.49  ? 406 VAL E C   1 
ATOM   7075 O O   . VAL D 2 167 ? 199.398 186.142 298.828 1.00 76.97  ? 406 VAL E O   1 
ATOM   7076 C CB  . VAL D 2 167 ? 201.958 185.502 297.681 1.00 61.92  ? 406 VAL E CB  1 
ATOM   7077 C CG1 . VAL D 2 167 ? 203.324 185.644 297.045 1.00 63.24  ? 406 VAL E CG1 1 
ATOM   7078 C CG2 . VAL D 2 167 ? 201.796 184.117 298.281 1.00 70.18  ? 406 VAL E CG2 1 
ATOM   7079 N N   . SER D 2 168 ? 200.453 186.421 300.814 1.00 87.98  ? 407 SER E N   1 
ATOM   7080 C CA  . SER D 2 168 ? 199.337 186.234 301.741 1.00 89.99  ? 407 SER E CA  1 
ATOM   7081 C C   . SER D 2 168 ? 199.122 184.759 302.040 1.00 92.80  ? 407 SER E C   1 
ATOM   7082 O O   . SER D 2 168 ? 198.101 184.377 302.619 1.00 91.47  ? 407 SER E O   1 
ATOM   7083 C CB  . SER D 2 168 ? 198.041 186.869 301.226 1.00 91.11  ? 407 SER E CB  1 
ATOM   7084 O OG  . SER D 2 168 ? 197.355 185.989 300.354 1.00 96.21  ? 407 SER E OG  1 
ATOM   7085 N N   . SER D 2 169 ? 200.075 183.931 301.646 1.00 93.35  ? 408 SER E N   1 
ATOM   7086 C CA  . SER D 2 169 ? 200.212 182.622 302.260 1.00 90.16  ? 408 SER E CA  1 
ATOM   7087 C C   . SER D 2 169 ? 200.764 182.827 303.664 1.00 90.53  ? 408 SER E C   1 
ATOM   7088 O O   . SER D 2 169 ? 201.946 183.168 303.804 1.00 87.67  ? 408 SER E O   1 
ATOM   7089 C CB  . SER D 2 169 ? 201.138 181.733 301.437 1.00 89.89  ? 408 SER E CB  1 
ATOM   7090 O OG  . SER D 2 169 ? 201.544 180.597 302.180 1.00 94.40  ? 408 SER E OG  1 
ATOM   7091 N N   . PRO D 2 170 ? 199.969 182.636 304.722 1.00 94.86  ? 409 PRO E N   1 
ATOM   7092 C CA  . PRO D 2 170 ? 200.421 183.013 306.070 1.00 96.11  ? 409 PRO E CA  1 
ATOM   7093 C C   . PRO D 2 170 ? 201.525 182.132 306.632 1.00 99.07  ? 409 PRO E C   1 
ATOM   7094 O O   . PRO D 2 170 ? 201.911 182.321 307.791 1.00 98.82  ? 409 PRO E O   1 
ATOM   7095 C CB  . PRO D 2 170 ? 199.141 182.895 306.907 1.00 93.28  ? 409 PRO E CB  1 
ATOM   7096 C CG  . PRO D 2 170 ? 198.328 181.876 306.198 1.00 91.55  ? 409 PRO E CG  1 
ATOM   7097 C CD  . PRO D 2 170 ? 198.626 182.033 304.733 1.00 93.66  ? 409 PRO E CD  1 
ATOM   7098 N N   . ASP D 2 171 ? 202.046 181.183 305.858 1.00 109.05 ? 410 ASP E N   1 
ATOM   7099 C CA  . ASP D 2 171 ? 203.146 180.331 306.282 1.00 108.65 ? 410 ASP E CA  1 
ATOM   7100 C C   . ASP D 2 171 ? 204.508 180.922 305.940 1.00 109.91 ? 410 ASP E C   1 
ATOM   7101 O O   . ASP D 2 171 ? 205.531 180.262 306.148 1.00 111.69 ? 410 ASP E O   1 
ATOM   7102 C CB  . ASP D 2 171 ? 202.984 178.933 305.670 1.00 108.59 ? 410 ASP E CB  1 
ATOM   7103 C CG  . ASP D 2 171 ? 203.522 178.835 304.248 1.00 110.70 ? 410 ASP E CG  1 
ATOM   7104 O OD1 . ASP D 2 171 ? 204.754 178.749 304.059 1.00 111.27 ? 410 ASP E OD1 1 
ATOM   7105 O OD2 . ASP D 2 171 ? 202.700 178.844 303.308 1.00 110.82 ? 410 ASP E OD2 1 
ATOM   7106 N N   . ARG D 2 172 ? 204.545 182.161 305.451 1.00 90.38  ? 411 ARG E N   1 
ATOM   7107 C CA  . ARG D 2 172 ? 205.780 182.755 304.954 1.00 85.98  ? 411 ARG E CA  1 
ATOM   7108 C C   . ARG D 2 172 ? 206.088 184.058 305.679 1.00 89.07  ? 411 ARG E C   1 
ATOM   7109 O O   . ARG D 2 172 ? 206.315 185.092 305.042 1.00 92.17  ? 411 ARG E O   1 
ATOM   7110 C CB  . ARG D 2 172 ? 205.692 182.982 303.445 1.00 78.96  ? 411 ARG E CB  1 
ATOM   7111 C CG  . ARG D 2 172 ? 205.587 181.696 302.643 1.00 84.80  ? 411 ARG E CG  1 
ATOM   7112 C CD  . ARG D 2 172 ? 205.293 181.961 301.177 1.00 85.11  ? 411 ARG E CD  1 
ATOM   7113 N NE  . ARG D 2 172 ? 204.784 180.770 300.507 1.00 85.40  ? 411 ARG E NE  1 
ATOM   7114 C CZ  . ARG D 2 172 ? 204.307 180.752 299.270 1.00 83.83  ? 411 ARG E CZ  1 
ATOM   7115 N NH1 . ARG D 2 172 ? 204.262 181.847 298.530 1.00 87.64  ? 411 ARG E NH1 1 
ATOM   7116 N NH2 . ARG D 2 172 ? 203.864 179.606 298.762 1.00 83.69  ? 411 ARG E NH2 1 
ATOM   7117 N N   . ILE D 2 173 ? 206.053 184.012 307.014 1.00 84.77  ? 412 ILE E N   1 
ATOM   7118 C CA  . ILE D 2 173 ? 206.446 185.144 307.847 1.00 77.96  ? 412 ILE E CA  1 
ATOM   7119 C C   . ILE D 2 173 ? 207.772 185.716 307.367 1.00 79.09  ? 412 ILE E C   1 
ATOM   7120 O O   . ILE D 2 173 ? 208.731 184.979 307.112 1.00 83.05  ? 412 ILE E O   1 
ATOM   7121 C CB  . ILE D 2 173 ? 206.521 184.706 309.321 1.00 78.92  ? 412 ILE E CB  1 
ATOM   7122 C CG1 . ILE D 2 173 ? 207.060 185.837 310.195 1.00 80.43  ? 412 ILE E CG1 1 
ATOM   7123 C CG2 . ILE D 2 173 ? 207.364 183.447 309.475 1.00 80.18  ? 412 ILE E CG2 1 
ATOM   7124 C CD1 . ILE D 2 173 ? 206.166 187.035 310.238 1.00 81.54  ? 412 ILE E CD1 1 
ATOM   7125 N N   . LEU D 2 174 ? 207.824 187.039 307.231 1.00 67.82  ? 413 LEU E N   1 
ATOM   7126 C CA  . LEU D 2 174 ? 209.036 187.711 306.786 1.00 69.70  ? 413 LEU E CA  1 
ATOM   7127 C C   . LEU D 2 174 ? 209.788 188.251 307.992 1.00 71.74  ? 413 LEU E C   1 
ATOM   7128 O O   . LEU D 2 174 ? 209.308 189.195 308.634 1.00 76.97  ? 413 LEU E O   1 
ATOM   7129 C CB  . LEU D 2 174 ? 208.704 188.845 305.834 1.00 66.88  ? 413 LEU E CB  1 
ATOM   7130 C CG  . LEU D 2 174 ? 208.141 188.448 304.471 1.00 64.06  ? 413 LEU E CG  1 
ATOM   7131 C CD1 . LEU D 2 174 ? 207.445 189.626 303.826 1.00 69.01  ? 413 LEU E CD1 1 
ATOM   7132 C CD2 . LEU D 2 174 ? 209.248 187.924 303.575 1.00 65.19  ? 413 LEU E CD2 1 
ATOM   7133 N N   . PRO D 2 175 ? 210.948 187.705 308.332 1.00 72.13  ? 414 PRO E N   1 
ATOM   7134 C CA  . PRO D 2 175 ? 211.691 188.174 309.513 1.00 72.39  ? 414 PRO E CA  1 
ATOM   7135 C C   . PRO D 2 175 ? 212.549 189.401 309.218 1.00 73.59  ? 414 PRO E C   1 
ATOM   7136 O O   . PRO D 2 175 ? 213.776 189.383 309.345 1.00 75.30  ? 414 PRO E O   1 
ATOM   7137 C CB  . PRO D 2 175 ? 212.531 186.943 309.874 1.00 70.38  ? 414 PRO E CB  1 
ATOM   7138 C CG  . PRO D 2 175 ? 212.811 186.306 308.556 1.00 72.83  ? 414 PRO E CG  1 
ATOM   7139 C CD  . PRO D 2 175 ? 211.592 186.542 307.698 1.00 70.41  ? 414 PRO E CD  1 
ATOM   7140 N N   . LEU D 2 176 ? 211.899 190.490 308.817 1.00 72.74  ? 415 LEU E N   1 
ATOM   7141 C CA  . LEU D 2 176 ? 212.614 191.731 308.547 1.00 74.06  ? 415 LEU E CA  1 
ATOM   7142 C C   . LEU D 2 176 ? 212.874 192.456 309.860 1.00 74.78  ? 415 LEU E C   1 
ATOM   7143 O O   . LEU D 2 176 ? 211.933 192.824 310.572 1.00 75.07  ? 415 LEU E O   1 
ATOM   7144 C CB  . LEU D 2 176 ? 211.830 192.614 307.582 1.00 67.71  ? 415 LEU E CB  1 
ATOM   7145 C CG  . LEU D 2 176 ? 212.439 192.790 306.189 1.00 72.63  ? 415 LEU E CG  1 
ATOM   7146 C CD1 . LEU D 2 176 ? 211.740 193.901 305.428 1.00 73.24  ? 415 LEU E CD1 1 
ATOM   7147 C CD2 . LEU D 2 176 ? 213.929 193.067 306.281 1.00 70.82  ? 415 LEU E CD2 1 
ATOM   7148 N N   . LYS D 2 177 ? 214.150 192.665 310.173 1.00 75.97  ? 416 LYS E N   1 
ATOM   7149 C CA  . LYS D 2 177 ? 214.574 193.210 311.453 1.00 75.49  ? 416 LYS E CA  1 
ATOM   7150 C C   . LYS D 2 177 ? 214.383 194.715 311.559 1.00 73.43  ? 416 LYS E C   1 
ATOM   7151 O O   . LYS D 2 177 ? 214.444 195.254 312.668 1.00 77.19  ? 416 LYS E O   1 
ATOM   7152 C CB  . LYS D 2 177 ? 216.043 192.861 311.702 1.00 75.87  ? 416 LYS E CB  1 
ATOM   7153 C CG  . LYS D 2 177 ? 216.864 192.763 310.431 1.00 75.76  ? 416 LYS E CG  1 
ATOM   7154 C CD  . LYS D 2 177 ? 218.102 191.913 310.639 1.00 76.85  ? 416 LYS E CD  1 
ATOM   7155 C CE  . LYS D 2 177 ? 217.817 190.454 310.330 1.00 75.35  ? 416 LYS E CE  1 
ATOM   7156 N NZ  . LYS D 2 177 ? 217.212 190.285 308.980 1.00 76.62  ? 416 LYS E NZ  1 
ATOM   7157 N N   . GLU D 2 178 ? 214.152 195.405 310.447 1.00 65.68  ? 417 GLU E N   1 
ATOM   7158 C CA  . GLU D 2 178 ? 213.974 196.848 310.468 1.00 67.38  ? 417 GLU E CA  1 
ATOM   7159 C C   . GLU D 2 178 ? 212.720 197.220 309.691 1.00 66.30  ? 417 GLU E C   1 
ATOM   7160 O O   . GLU D 2 178 ? 212.312 196.518 308.764 1.00 70.69  ? 417 GLU E O   1 
ATOM   7161 C CB  . GLU D 2 178 ? 215.212 197.575 309.911 1.00 67.34  ? 417 GLU E CB  1 
ATOM   7162 C CG  . GLU D 2 178 ? 215.084 198.156 308.506 1.00 66.69  ? 417 GLU E CG  1 
ATOM   7163 C CD  . GLU D 2 178 ? 214.976 197.109 307.405 1.00 74.32  ? 417 GLU E CD  1 
ATOM   7164 O OE1 . GLU D 2 178 ? 214.801 195.910 307.705 1.00 76.76  ? 417 GLU E OE1 1 
ATOM   7165 O OE2 . GLU D 2 178 ? 215.067 197.496 306.221 1.00 75.13  ? 417 GLU E OE2 1 
ATOM   7166 N N   . SER D 2 179 ? 212.102 198.325 310.097 1.00 60.50  ? 418 SER E N   1 
ATOM   7167 C CA  . SER D 2 179 ? 210.861 198.777 309.484 1.00 61.35  ? 418 SER E CA  1 
ATOM   7168 C C   . SER D 2 179 ? 211.161 199.417 308.135 1.00 60.44  ? 418 SER E C   1 
ATOM   7169 O O   . SER D 2 179 ? 212.150 200.143 307.990 1.00 62.60  ? 418 SER E O   1 
ATOM   7170 C CB  . SER D 2 179 ? 210.138 199.758 310.402 1.00 67.32  ? 418 SER E CB  1 
ATOM   7171 O OG  . SER D 2 179 ? 209.184 199.087 311.205 1.00 64.82  ? 418 SER E OG  1 
ATOM   7172 N N   . LEU D 2 180 ? 210.307 199.152 307.153 1.00 65.13  ? 419 LEU E N   1 
ATOM   7173 C CA  . LEU D 2 180 ? 210.568 199.594 305.792 1.00 68.16  ? 419 LEU E CA  1 
ATOM   7174 C C   . LEU D 2 180 ? 210.042 201.004 305.567 1.00 67.09  ? 419 LEU E C   1 
ATOM   7175 O O   . LEU D 2 180 ? 209.037 201.413 306.154 1.00 70.20  ? 419 LEU E O   1 
ATOM   7176 C CB  . LEU D 2 180 ? 209.918 198.636 304.795 1.00 70.93  ? 419 LEU E CB  1 
ATOM   7177 C CG  . LEU D 2 180 ? 210.753 197.438 304.351 1.00 70.32  ? 419 LEU E CG  1 
ATOM   7178 C CD1 . LEU D 2 180 ? 210.006 196.622 303.308 1.00 71.45  ? 419 LEU E CD1 1 
ATOM   7179 C CD2 . LEU D 2 180 ? 212.083 197.901 303.818 1.00 63.44  ? 419 LEU E CD2 1 
ATOM   7180 N N   . CYS D 2 181 ? 210.732 201.749 304.709 1.00 66.09  ? 420 CYS E N   1 
ATOM   7181 C CA  . CYS D 2 181 ? 210.270 203.049 304.239 1.00 64.56  ? 420 CYS E CA  1 
ATOM   7182 C C   . CYS D 2 181 ? 210.077 203.098 302.734 1.00 65.92  ? 420 CYS E C   1 
ATOM   7183 O O   . CYS D 2 181 ? 209.032 203.552 302.264 1.00 65.87  ? 420 CYS E O   1 
ATOM   7184 C CB  . CYS D 2 181 ? 211.256 204.145 304.651 1.00 67.18  ? 420 CYS E CB  1 
ATOM   7185 S SG  . CYS D 2 181 ? 212.987 203.679 304.489 1.00 87.64  ? 420 CYS E SG  1 
ATOM   7186 N N   . ARG D 2 182 ? 211.064 202.639 301.970 1.00 54.24  ? 421 ARG E N   1 
ATOM   7187 C CA  . ARG D 2 182 ? 210.997 202.582 300.518 1.00 52.41  ? 421 ARG E CA  1 
ATOM   7188 C C   . ARG D 2 182 ? 211.139 201.134 300.077 1.00 56.96  ? 421 ARG E C   1 
ATOM   7189 O O   . ARG D 2 182 ? 212.055 200.435 300.521 1.00 59.87  ? 421 ARG E O   1 
ATOM   7190 C CB  . ARG D 2 182 ? 212.091 203.441 299.883 1.00 49.82  ? 421 ARG E CB  1 
ATOM   7191 C CG  . ARG D 2 182 ? 211.644 204.841 299.513 1.00 48.79  ? 421 ARG E CG  1 
ATOM   7192 C CD  . ARG D 2 182 ? 212.337 205.326 298.254 1.00 43.39  ? 421 ARG E CD  1 
ATOM   7193 N NE  . ARG D 2 182 ? 213.776 205.457 298.446 1.00 49.16  ? 421 ARG E NE  1 
ATOM   7194 C CZ  . ARG D 2 182 ? 214.649 205.640 297.466 1.00 54.39  ? 421 ARG E CZ  1 
ATOM   7195 N NH1 . ARG D 2 182 ? 214.263 205.720 296.204 1.00 57.33  ? 421 ARG E NH1 1 
ATOM   7196 N NH2 . ARG D 2 182 ? 215.942 205.744 297.760 1.00 51.50  ? 421 ARG E NH2 1 
ATOM   7197 N N   . VAL D 2 183 ? 210.241 200.690 299.203 1.00 57.09  ? 422 VAL E N   1 
ATOM   7198 C CA  . VAL D 2 183 ? 210.210 199.308 298.741 1.00 48.86  ? 422 VAL E CA  1 
ATOM   7199 C C   . VAL D 2 183 ? 210.338 199.293 297.225 1.00 52.04  ? 422 VAL E C   1 
ATOM   7200 O O   . VAL D 2 183 ? 209.694 200.087 296.532 1.00 58.08  ? 422 VAL E O   1 
ATOM   7201 C CB  . VAL D 2 183 ? 208.923 198.589 299.198 1.00 51.57  ? 422 VAL E CB  1 
ATOM   7202 C CG1 . VAL D 2 183 ? 207.704 199.447 298.914 1.00 57.89  ? 422 VAL E CG1 1 
ATOM   7203 C CG2 . VAL D 2 183 ? 208.794 197.235 298.525 1.00 54.32  ? 422 VAL E CG2 1 
ATOM   7204 N N   . GLY D 2 184 ? 211.174 198.397 296.709 1.00 45.63  ? 423 GLY E N   1 
ATOM   7205 C CA  . GLY D 2 184 ? 211.418 198.288 295.282 1.00 42.72  ? 423 GLY E CA  1 
ATOM   7206 C C   . GLY D 2 184 ? 210.825 197.003 294.727 1.00 45.56  ? 423 GLY E C   1 
ATOM   7207 O O   . GLY D 2 184 ? 211.056 195.921 295.264 1.00 50.22  ? 423 GLY E O   1 
ATOM   7208 N N   . VAL D 2 185 ? 210.063 197.143 293.648 1.00 40.73  ? 424 VAL E N   1 
ATOM   7209 C CA  . VAL D 2 185 ? 209.444 196.018 292.959 1.00 35.77  ? 424 VAL E CA  1 
ATOM   7210 C C   . VAL D 2 185 ? 210.187 195.806 291.649 1.00 40.89  ? 424 VAL E C   1 
ATOM   7211 O O   . VAL D 2 185 ? 210.370 196.753 290.873 1.00 51.44  ? 424 VAL E O   1 
ATOM   7212 C CB  . VAL D 2 185 ? 207.948 196.257 292.712 1.00 40.26  ? 424 VAL E CB  1 
ATOM   7213 C CG1 . VAL D 2 185 ? 207.296 194.989 292.194 1.00 38.77  ? 424 VAL E CG1 1 
ATOM   7214 C CG2 . VAL D 2 185 ? 207.276 196.736 293.986 1.00 40.96  ? 424 VAL E CG2 1 
ATOM   7215 N N   . PHE D 2 186 ? 210.605 194.566 291.403 1.00 35.09  ? 425 PHE E N   1 
ATOM   7216 C CA  . PHE D 2 186 ? 211.417 194.200 290.251 1.00 44.83  ? 425 PHE E CA  1 
ATOM   7217 C C   . PHE D 2 186 ? 210.720 193.099 289.465 1.00 46.65  ? 425 PHE E C   1 
ATOM   7218 O O   . PHE D 2 186 ? 210.221 192.132 290.048 1.00 55.26  ? 425 PHE E O   1 
ATOM   7219 C CB  . PHE D 2 186 ? 212.802 193.731 290.708 1.00 46.99  ? 425 PHE E CB  1 
ATOM   7220 C CG  . PHE D 2 186 ? 213.738 193.388 289.587 1.00 48.45  ? 425 PHE E CG  1 
ATOM   7221 C CD1 . PHE D 2 186 ? 213.791 192.104 289.077 1.00 47.98  ? 425 PHE E CD1 1 
ATOM   7222 C CD2 . PHE D 2 186 ? 214.588 194.342 289.064 1.00 47.59  ? 425 PHE E CD2 1 
ATOM   7223 C CE1 . PHE D 2 186 ? 214.659 191.785 288.056 1.00 45.59  ? 425 PHE E CE1 1 
ATOM   7224 C CE2 . PHE D 2 186 ? 215.459 194.026 288.043 1.00 46.62  ? 425 PHE E CE2 1 
ATOM   7225 C CZ  . PHE D 2 186 ? 215.494 192.747 287.539 1.00 41.79  ? 425 PHE E CZ  1 
ATOM   7226 N N   . LEU D 2 187 ? 210.711 193.235 288.140 1.00 38.13  ? 426 LEU E N   1 
ATOM   7227 C CA  . LEU D 2 187 ? 209.978 192.342 287.260 1.00 38.12  ? 426 LEU E CA  1 
ATOM   7228 C C   . LEU D 2 187 ? 210.870 191.912 286.108 1.00 46.06  ? 426 LEU E C   1 
ATOM   7229 O O   . LEU D 2 187 ? 211.576 192.728 285.509 1.00 60.97  ? 426 LEU E O   1 
ATOM   7230 C CB  . LEU D 2 187 ? 208.716 193.022 286.714 1.00 43.29  ? 426 LEU E CB  1 
ATOM   7231 C CG  . LEU D 2 187 ? 207.788 192.228 285.797 1.00 44.23  ? 426 LEU E CG  1 
ATOM   7232 C CD1 . LEU D 2 187 ? 206.358 192.563 286.129 1.00 48.60  ? 426 LEU E CD1 1 
ATOM   7233 C CD2 . LEU D 2 187 ? 208.067 192.537 284.339 1.00 48.21  ? 426 LEU E CD2 1 
ATOM   7234 N N   . ASP D 2 188 ? 210.814 190.619 285.796 1.00 45.21  ? 427 ASP E N   1 
ATOM   7235 C CA  . ASP D 2 188 ? 211.596 190.044 284.704 1.00 54.74  ? 427 ASP E CA  1 
ATOM   7236 C C   . ASP D 2 188 ? 210.677 189.069 283.975 1.00 54.52  ? 427 ASP E C   1 
ATOM   7237 O O   . ASP D 2 188 ? 210.347 188.006 284.509 1.00 64.04  ? 427 ASP E O   1 
ATOM   7238 C CB  . ASP D 2 188 ? 212.847 189.355 285.231 1.00 62.29  ? 427 ASP E CB  1 
ATOM   7239 C CG  . ASP D 2 188 ? 213.890 189.145 284.160 1.00 65.03  ? 427 ASP E CG  1 
ATOM   7240 O OD1 . ASP D 2 188 ? 213.565 189.338 282.971 1.00 65.95  ? 427 ASP E OD1 1 
ATOM   7241 O OD2 . ASP D 2 188 ? 215.034 188.783 284.506 1.00 64.95  ? 427 ASP E OD2 1 
ATOM   7242 N N   . TYR D 2 189 ? 210.265 189.441 282.761 1.00 47.05  ? 428 TYR E N   1 
ATOM   7243 C CA  . TYR D 2 189 ? 209.242 188.673 282.060 1.00 54.88  ? 428 TYR E CA  1 
ATOM   7244 C C   . TYR D 2 189 ? 209.790 187.360 281.512 1.00 60.84  ? 428 TYR E C   1 
ATOM   7245 O O   . TYR D 2 189 ? 209.102 186.333 281.551 1.00 58.75  ? 428 TYR E O   1 
ATOM   7246 C CB  . TYR D 2 189 ? 208.645 189.512 280.935 1.00 50.07  ? 428 TYR E CB  1 
ATOM   7247 C CG  . TYR D 2 189 ? 207.209 189.176 280.620 1.00 48.79  ? 428 TYR E CG  1 
ATOM   7248 C CD1 . TYR D 2 189 ? 206.893 188.132 279.765 1.00 51.81  ? 428 TYR E CD1 1 
ATOM   7249 C CD2 . TYR D 2 189 ? 206.169 189.905 281.176 1.00 50.49  ? 428 TYR E CD2 1 
ATOM   7250 C CE1 . TYR D 2 189 ? 205.582 187.824 279.473 1.00 57.76  ? 428 TYR E CE1 1 
ATOM   7251 C CE2 . TYR D 2 189 ? 204.856 189.604 280.890 1.00 49.32  ? 428 TYR E CE2 1 
ATOM   7252 C CZ  . TYR D 2 189 ? 204.567 188.563 280.039 1.00 58.04  ? 428 TYR E CZ  1 
ATOM   7253 O OH  . TYR D 2 189 ? 203.257 188.259 279.751 1.00 65.31  ? 428 TYR E OH  1 
ATOM   7254 N N   . GLU D 2 190 ? 211.017 187.373 280.988 1.00 59.32  ? 429 GLU E N   1 
ATOM   7255 C CA  . GLU D 2 190 ? 211.563 186.172 280.361 1.00 53.76  ? 429 GLU E CA  1 
ATOM   7256 C C   . GLU D 2 190 ? 211.729 185.040 281.368 1.00 56.68  ? 429 GLU E C   1 
ATOM   7257 O O   . GLU D 2 190 ? 211.406 183.885 281.070 1.00 58.83  ? 429 GLU E O   1 
ATOM   7258 C CB  . GLU D 2 190 ? 212.898 186.491 279.689 1.00 53.57  ? 429 GLU E CB  1 
ATOM   7259 C CG  . GLU D 2 190 ? 213.816 187.368 280.518 1.00 57.58  ? 429 GLU E CG  1 
ATOM   7260 C CD  . GLU D 2 190 ? 215.043 187.820 279.756 1.00 58.61  ? 429 GLU E CD  1 
ATOM   7261 O OE1 . GLU D 2 190 ? 214.918 188.116 278.550 1.00 62.56  ? 429 GLU E OE1 1 
ATOM   7262 O OE2 . GLU D 2 190 ? 216.131 187.885 280.363 1.00 54.97  ? 429 GLU E OE2 1 
ATOM   7263 N N   . ALA D 2 191 ? 212.226 185.348 282.563 1.00 49.50  ? 430 ALA E N   1 
ATOM   7264 C CA  . ALA D 2 191 ? 212.505 184.338 283.573 1.00 47.52  ? 430 ALA E CA  1 
ATOM   7265 C C   . ALA D 2 191 ? 211.419 184.245 284.637 1.00 54.30  ? 430 ALA E C   1 
ATOM   7266 O O   . ALA D 2 191 ? 211.589 183.509 285.613 1.00 60.30  ? 430 ALA E O   1 
ATOM   7267 C CB  . ALA D 2 191 ? 213.859 184.610 284.231 1.00 44.42  ? 430 ALA E CB  1 
ATOM   7268 N N   . GLY D 2 192 ? 210.314 184.968 284.474 1.00 52.75  ? 431 GLY E N   1 
ATOM   7269 C CA  . GLY D 2 192 ? 209.213 184.888 285.415 1.00 54.51  ? 431 GLY E CA  1 
ATOM   7270 C C   . GLY D 2 192 ? 209.588 185.296 286.824 1.00 53.95  ? 431 GLY E C   1 
ATOM   7271 O O   . GLY D 2 192 ? 209.253 184.604 287.789 1.00 55.13  ? 431 GLY E O   1 
ATOM   7272 N N   . ASP D 2 193 ? 210.280 186.421 286.954 1.00 56.87  ? 432 ASP E N   1 
ATOM   7273 C CA  . ASP D 2 193 ? 210.871 186.848 288.215 1.00 59.11  ? 432 ASP E CA  1 
ATOM   7274 C C   . ASP D 2 193 ? 210.103 188.044 288.758 1.00 57.91  ? 432 ASP E C   1 
ATOM   7275 O O   . ASP D 2 193 ? 209.980 189.066 288.077 1.00 63.87  ? 432 ASP E O   1 
ATOM   7276 C CB  . ASP D 2 193 ? 212.343 187.200 288.012 1.00 65.41  ? 432 ASP E CB  1 
ATOM   7277 C CG  . ASP D 2 193 ? 213.147 187.109 289.283 1.00 68.90  ? 432 ASP E CG  1 
ATOM   7278 O OD1 . ASP D 2 193 ? 212.785 187.785 290.267 1.00 72.56  ? 432 ASP E OD1 1 
ATOM   7279 O OD2 . ASP D 2 193 ? 214.155 186.373 289.291 1.00 63.61  ? 432 ASP E OD2 1 
ATOM   7280 N N   . VAL D 2 194 ? 209.593 187.919 289.980 1.00 44.94  ? 433 VAL E N   1 
ATOM   7281 C CA  . VAL D 2 194 ? 208.954 189.022 290.690 1.00 47.71  ? 433 VAL E CA  1 
ATOM   7282 C C   . VAL D 2 194 ? 209.652 189.157 292.034 1.00 48.18  ? 433 VAL E C   1 
ATOM   7283 O O   . VAL D 2 194 ? 209.387 188.380 292.961 1.00 53.35  ? 433 VAL E O   1 
ATOM   7284 C CB  . VAL D 2 194 ? 207.447 188.805 290.871 1.00 52.38  ? 433 VAL E CB  1 
ATOM   7285 C CG1 . VAL D 2 194 ? 206.841 189.967 291.636 1.00 52.45  ? 433 VAL E CG1 1 
ATOM   7286 C CG2 . VAL D 2 194 ? 206.770 188.643 289.522 1.00 55.11  ? 433 VAL E CG2 1 
ATOM   7287 N N   . SER D 2 195 ? 210.529 190.147 292.149 1.00 45.75  ? 434 SER E N   1 
ATOM   7288 C CA  . SER D 2 195 ? 211.366 190.322 293.325 1.00 50.63  ? 434 SER E CA  1 
ATOM   7289 C C   . SER D 2 195 ? 210.976 191.582 294.085 1.00 52.41  ? 434 SER E C   1 
ATOM   7290 O O   . SER D 2 195 ? 210.490 192.558 293.505 1.00 64.16  ? 434 SER E O   1 
ATOM   7291 C CB  . SER D 2 195 ? 212.847 190.397 292.941 1.00 52.95  ? 434 SER E CB  1 
ATOM   7292 O OG  . SER D 2 195 ? 213.276 189.208 292.307 1.00 43.68  ? 434 SER E OG  1 
ATOM   7293 N N   . PHE D 2 196 ? 211.204 191.552 295.393 1.00 28.97  ? 435 PHE E N   1 
ATOM   7294 C CA  . PHE D 2 196 ? 211.015 192.704 296.258 1.00 36.96  ? 435 PHE E CA  1 
ATOM   7295 C C   . PHE D 2 196 ? 212.330 193.032 296.947 1.00 42.78  ? 435 PHE E C   1 
ATOM   7296 O O   . PHE D 2 196 ? 213.062 192.132 297.368 1.00 46.66  ? 435 PHE E O   1 
ATOM   7297 C CB  . PHE D 2 196 ? 209.925 192.441 297.295 1.00 43.76  ? 435 PHE E CB  1 
ATOM   7298 C CG  . PHE D 2 196 ? 208.565 192.230 296.701 1.00 42.06  ? 435 PHE E CG  1 
ATOM   7299 C CD1 . PHE D 2 196 ? 207.906 193.263 296.065 1.00 38.70  ? 435 PHE E CD1 1 
ATOM   7300 C CD2 . PHE D 2 196 ? 207.945 190.996 296.784 1.00 47.30  ? 435 PHE E CD2 1 
ATOM   7301 C CE1 . PHE D 2 196 ? 206.656 193.070 295.520 1.00 41.71  ? 435 PHE E CE1 1 
ATOM   7302 C CE2 . PHE D 2 196 ? 206.695 190.798 296.242 1.00 40.61  ? 435 PHE E CE2 1 
ATOM   7303 C CZ  . PHE D 2 196 ? 206.050 191.836 295.609 1.00 43.40  ? 435 PHE E CZ  1 
ATOM   7304 N N   . TYR D 2 197 ? 212.627 194.323 297.053 1.00 38.52  ? 436 TYR E N   1 
ATOM   7305 C CA  . TYR D 2 197 ? 213.884 194.806 297.598 1.00 38.54  ? 436 TYR E CA  1 
ATOM   7306 C C   . TYR D 2 197 ? 213.618 195.902 298.619 1.00 43.31  ? 436 TYR E C   1 
ATOM   7307 O O   . TYR D 2 197 ? 212.638 196.644 298.516 1.00 45.57  ? 436 TYR E O   1 
ATOM   7308 C CB  . TYR D 2 197 ? 214.800 195.363 296.498 1.00 43.70  ? 436 TYR E CB  1 
ATOM   7309 C CG  . TYR D 2 197 ? 215.518 194.330 295.662 1.00 39.37  ? 436 TYR E CG  1 
ATOM   7310 C CD1 . TYR D 2 197 ? 214.824 193.511 294.785 1.00 37.33  ? 436 TYR E CD1 1 
ATOM   7311 C CD2 . TYR D 2 197 ? 216.897 194.197 295.726 1.00 40.99  ? 436 TYR E CD2 1 
ATOM   7312 C CE1 . TYR D 2 197 ? 215.480 192.578 294.014 1.00 38.06  ? 436 TYR E CE1 1 
ATOM   7313 C CE2 . TYR D 2 197 ? 217.562 193.268 294.957 1.00 36.62  ? 436 TYR E CE2 1 
ATOM   7314 C CZ  . TYR D 2 197 ? 216.848 192.460 294.103 1.00 36.81  ? 436 TYR E CZ  1 
ATOM   7315 O OH  . TYR D 2 197 ? 217.507 191.531 293.335 1.00 40.47  ? 436 TYR E OH  1 
ATOM   7316 N N   . ASN D 2 198 ? 214.515 196.005 299.596 1.00 51.03  ? 437 ASN E N   1 
ATOM   7317 C CA  . ASN D 2 198 ? 214.516 197.094 300.567 1.00 52.93  ? 437 ASN E CA  1 
ATOM   7318 C C   . ASN D 2 198 ? 215.392 198.206 300.006 1.00 59.78  ? 437 ASN E C   1 
ATOM   7319 O O   . ASN D 2 198 ? 216.619 198.081 299.976 1.00 60.76  ? 437 ASN E O   1 
ATOM   7320 C CB  . ASN D 2 198 ? 215.024 196.608 301.923 1.00 52.71  ? 437 ASN E CB  1 
ATOM   7321 C CG  . ASN D 2 198 ? 215.356 197.744 302.870 1.00 59.55  ? 437 ASN E CG  1 
ATOM   7322 O OD1 . ASN D 2 198 ? 214.824 198.847 302.757 1.00 64.26  ? 437 ASN E OD1 1 
ATOM   7323 N ND2 . ASN D 2 198 ? 216.246 197.474 303.817 1.00 60.31  ? 437 ASN E ND2 1 
ATOM   7324 N N   . MET D 2 199 ? 214.763 199.303 299.584 1.00 49.73  ? 438 MET E N   1 
ATOM   7325 C CA  . MET D 2 199 ? 215.448 200.318 298.794 1.00 43.06  ? 438 MET E CA  1 
ATOM   7326 C C   . MET D 2 199 ? 216.388 201.198 299.606 1.00 47.89  ? 438 MET E C   1 
ATOM   7327 O O   . MET D 2 199 ? 217.148 201.968 299.011 1.00 54.11  ? 438 MET E O   1 
ATOM   7328 C CB  . MET D 2 199 ? 214.425 201.189 298.071 1.00 47.97  ? 438 MET E CB  1 
ATOM   7329 C CG  . MET D 2 199 ? 214.155 200.799 296.617 1.00 53.84  ? 438 MET E CG  1 
ATOM   7330 S SD  . MET D 2 199 ? 215.601 200.546 295.560 1.00 55.78  ? 438 MET E SD  1 
ATOM   7331 C CE  . MET D 2 199 ? 215.932 198.796 295.756 1.00 46.84  ? 438 MET E CE  1 
ATOM   7332 N N   . ARG D 2 200 ? 216.354 201.121 300.936 1.00 48.31  ? 439 ARG E N   1 
ATOM   7333 C CA  . ARG D 2 200 ? 217.363 201.819 301.725 1.00 52.87  ? 439 ARG E CA  1 
ATOM   7334 C C   . ARG D 2 200 ? 218.754 201.267 301.450 1.00 56.61  ? 439 ARG E C   1 
ATOM   7335 O O   . ARG D 2 200 ? 219.709 202.033 301.275 1.00 59.33  ? 439 ARG E O   1 
ATOM   7336 C CB  . ARG D 2 200 ? 217.035 201.720 303.212 1.00 54.32  ? 439 ARG E CB  1 
ATOM   7337 C CG  . ARG D 2 200 ? 218.214 202.011 304.126 1.00 54.78  ? 439 ARG E CG  1 
ATOM   7338 C CD  . ARG D 2 200 ? 217.784 202.240 305.567 1.00 52.79  ? 439 ARG E CD  1 
ATOM   7339 N NE  . ARG D 2 200 ? 216.778 201.281 306.010 1.00 56.38  ? 439 ARG E NE  1 
ATOM   7340 C CZ  . ARG D 2 200 ? 215.479 201.540 306.071 1.00 62.59  ? 439 ARG E CZ  1 
ATOM   7341 N NH1 . ARG D 2 200 ? 214.998 202.729 305.751 1.00 66.40  ? 439 ARG E NH1 1 
ATOM   7342 N NH2 . ARG D 2 200 ? 214.643 200.583 306.459 1.00 62.74  ? 439 ARG E NH2 1 
ATOM   7343 N N   . ASP D 2 201 ? 218.889 199.944 301.399 1.00 53.90  ? 440 ASP E N   1 
ATOM   7344 C CA  . ASP D 2 201 ? 220.170 199.308 301.139 1.00 53.07  ? 440 ASP E CA  1 
ATOM   7345 C C   . ASP D 2 201 ? 220.171 198.454 299.881 1.00 52.63  ? 440 ASP E C   1 
ATOM   7346 O O   . ASP D 2 201 ? 221.228 197.927 299.515 1.00 56.57  ? 440 ASP E O   1 
ATOM   7347 C CB  . ASP D 2 201 ? 220.593 198.448 302.336 1.00 57.00  ? 440 ASP E CB  1 
ATOM   7348 C CG  . ASP D 2 201 ? 219.459 197.607 302.872 1.00 64.08  ? 440 ASP E CG  1 
ATOM   7349 O OD1 . ASP D 2 201 ? 218.299 197.881 302.507 1.00 62.65  ? 440 ASP E OD1 1 
ATOM   7350 O OD2 . ASP D 2 201 ? 219.726 196.670 303.653 1.00 70.60  ? 440 ASP E OD2 1 
ATOM   7351 N N   . ARG D 2 202 ? 219.026 198.301 299.214 1.00 56.14  ? 441 ARG E N   1 
ATOM   7352 C CA  . ARG D 2 202 ? 218.918 197.508 297.991 1.00 59.51  ? 441 ARG E CA  1 
ATOM   7353 C C   . ARG D 2 202 ? 219.368 196.067 298.238 1.00 58.49  ? 441 ARG E C   1 
ATOM   7354 O O   . ARG D 2 202 ? 220.344 195.576 297.667 1.00 58.86  ? 441 ARG E O   1 
ATOM   7355 C CB  . ARG D 2 202 ? 219.699 198.168 296.850 0.00 58.26  ? 441 ARG E CB  1 
ATOM   7356 C CG  . ARG D 2 202 ? 219.357 199.643 296.666 1.00 58.65  ? 441 ARG E CG  1 
ATOM   7357 C CD  . ARG D 2 202 ? 220.223 200.292 295.606 1.00 56.07  ? 441 ARG E CD  1 
ATOM   7358 N NE  . ARG D 2 202 ? 219.575 200.367 294.304 1.00 56.19  ? 441 ARG E NE  1 
ATOM   7359 C CZ  . ARG D 2 202 ? 220.222 200.296 293.149 1.00 56.93  ? 441 ARG E CZ  1 
ATOM   7360 N NH1 . ARG D 2 202 ? 221.534 200.139 293.101 1.00 50.20  ? 441 ARG E NH1 1 
ATOM   7361 N NH2 . ARG D 2 202 ? 219.535 200.380 292.014 1.00 61.82  ? 441 ARG E NH2 1 
ATOM   7362 N N   . SER D 2 203 ? 218.624 195.396 299.117 1.00 56.97  ? 442 SER E N   1 
ATOM   7363 C CA  . SER D 2 203 ? 218.877 194.014 299.489 1.00 61.89  ? 442 SER E CA  1 
ATOM   7364 C C   . SER D 2 203 ? 217.609 193.198 299.293 1.00 60.17  ? 442 SER E C   1 
ATOM   7365 O O   . SER D 2 203 ? 216.497 193.731 299.335 1.00 62.70  ? 442 SER E O   1 
ATOM   7366 C CB  . SER D 2 203 ? 219.348 193.899 300.942 1.00 65.21  ? 442 SER E CB  1 
ATOM   7367 O OG  . SER D 2 203 ? 218.244 193.851 301.829 1.00 71.93  ? 442 SER E OG  1 
ATOM   7368 N N   . HIS D 2 204 ? 217.788 191.898 299.082 1.00 51.22  ? 443 HIS E N   1 
ATOM   7369 C CA  . HIS D 2 204 ? 216.672 191.032 298.729 1.00 51.27  ? 443 HIS E CA  1 
ATOM   7370 C C   . HIS D 2 204 ? 215.698 190.878 299.892 1.00 54.05  ? 443 HIS E C   1 
ATOM   7371 O O   . HIS D 2 204 ? 216.083 190.887 301.063 1.00 54.96  ? 443 HIS E O   1 
ATOM   7372 C CB  . HIS D 2 204 ? 217.183 189.661 298.294 1.00 50.31  ? 443 HIS E CB  1 
ATOM   7373 C CG  . HIS D 2 204 ? 216.146 188.817 297.625 1.00 54.68  ? 443 HIS E CG  1 
ATOM   7374 N ND1 . HIS D 2 204 ? 215.181 188.131 298.328 1.00 59.31  ? 443 HIS E ND1 1 
ATOM   7375 C CD2 . HIS D 2 204 ? 215.922 188.547 296.317 1.00 54.46  ? 443 HIS E CD2 1 
ATOM   7376 C CE1 . HIS D 2 204 ? 214.408 187.473 297.484 1.00 55.64  ? 443 HIS E CE1 1 
ATOM   7377 N NE2 . HIS D 2 204 ? 214.835 187.710 296.257 1.00 52.94  ? 443 HIS E NE2 1 
ATOM   7378 N N   . ILE D 2 205 ? 214.418 190.739 299.551 1.00 59.63  ? 444 ILE E N   1 
ATOM   7379 C CA  . ILE D 2 205 ? 213.365 190.533 300.538 1.00 62.67  ? 444 ILE E CA  1 
ATOM   7380 C C   . ILE D 2 205 ? 212.639 189.228 300.235 1.00 67.40  ? 444 ILE E C   1 
ATOM   7381 O O   . ILE D 2 205 ? 212.609 188.316 301.069 1.00 67.23  ? 444 ILE E O   1 
ATOM   7382 C CB  . ILE D 2 205 ? 212.386 191.721 300.567 1.00 56.74  ? 444 ILE E CB  1 
ATOM   7383 C CG1 . ILE D 2 205 ? 213.007 192.903 301.310 1.00 57.55  ? 444 ILE E CG1 1 
ATOM   7384 C CG2 . ILE D 2 205 ? 211.075 191.324 301.222 1.00 53.45  ? 444 ILE E CG2 1 
ATOM   7385 C CD1 . ILE D 2 205 ? 212.058 194.065 301.503 1.00 61.57  ? 444 ILE E CD1 1 
ATOM   7386 N N   . TYR D 2 206 ? 212.054 189.125 299.041 1.00 62.76  ? 445 TYR E N   1 
ATOM   7387 C CA  . TYR D 2 206 ? 211.302 187.936 298.661 1.00 55.71  ? 445 TYR E CA  1 
ATOM   7388 C C   . TYR D 2 206 ? 211.169 187.908 297.146 1.00 61.04  ? 445 TYR E C   1 
ATOM   7389 O O   . TYR D 2 206 ? 210.813 188.921 296.537 1.00 69.24  ? 445 TYR E O   1 
ATOM   7390 C CB  . TYR D 2 206 ? 209.909 187.929 299.306 1.00 56.69  ? 445 TYR E CB  1 
ATOM   7391 C CG  . TYR D 2 206 ? 209.124 186.649 299.101 1.00 58.37  ? 445 TYR E CG  1 
ATOM   7392 C CD1 . TYR D 2 206 ? 209.741 185.492 298.649 1.00 62.10  ? 445 TYR E CD1 1 
ATOM   7393 C CD2 . TYR D 2 206 ? 207.780 186.580 299.425 1.00 61.96  ? 445 TYR E CD2 1 
ATOM   7394 C CE1 . TYR D 2 206 ? 209.035 184.324 298.474 1.00 59.68  ? 445 TYR E CE1 1 
ATOM   7395 C CE2 . TYR D 2 206 ? 207.065 185.416 299.246 1.00 65.42  ? 445 TYR E CE2 1 
ATOM   7396 C CZ  . TYR D 2 206 ? 207.699 184.289 298.776 1.00 65.58  ? 445 TYR E CZ  1 
ATOM   7397 O OH  . TYR D 2 206 ? 206.992 183.122 298.607 1.00 68.54  ? 445 TYR E OH  1 
ATOM   7398 N N   . THR D 2 207 ? 211.448 186.755 296.545 1.00 63.01  ? 446 THR E N   1 
ATOM   7399 C CA  . THR D 2 207 ? 211.119 186.488 295.151 1.00 60.04  ? 446 THR E CA  1 
ATOM   7400 C C   . THR D 2 207 ? 209.952 185.516 295.094 1.00 56.58  ? 446 THR E C   1 
ATOM   7401 O O   . THR D 2 207 ? 210.041 184.406 295.629 1.00 63.98  ? 446 THR E O   1 
ATOM   7402 C CB  . THR D 2 207 ? 212.306 185.908 294.388 1.00 59.53  ? 446 THR E CB  1 
ATOM   7403 O OG1 . THR D 2 207 ? 213.527 186.474 294.877 1.00 58.97  ? 446 THR E OG1 1 
ATOM   7404 C CG2 . THR D 2 207 ? 212.153 186.188 292.908 1.00 61.03  ? 446 THR E CG2 1 
ATOM   7405 N N   . CYS D 2 208 ? 208.872 185.924 294.437 1.00 60.01  ? 447 CYS E N   1 
ATOM   7406 C CA  . CYS D 2 208 ? 207.761 185.013 294.237 1.00 65.46  ? 447 CYS E CA  1 
ATOM   7407 C C   . CYS D 2 208 ? 208.207 183.854 293.346 1.00 69.98  ? 447 CYS E C   1 
ATOM   7408 O O   . CYS D 2 208 ? 209.050 184.032 292.462 1.00 76.02  ? 447 CYS E O   1 
ATOM   7409 C CB  . CYS D 2 208 ? 206.576 185.737 293.608 1.00 66.82  ? 447 CYS E CB  1 
ATOM   7410 S SG  . CYS D 2 208 ? 205.746 186.894 294.714 1.00 85.72  ? 447 CYS E SG  1 
ATOM   7411 N N   . PRO D 2 209 ? 207.679 182.651 293.574 1.00 53.27  ? 448 PRO E N   1 
ATOM   7412 C CA  . PRO D 2 209 ? 208.082 181.507 292.749 1.00 50.25  ? 448 PRO E CA  1 
ATOM   7413 C C   . PRO D 2 209 ? 207.756 181.755 291.286 1.00 56.83  ? 448 PRO E C   1 
ATOM   7414 O O   . PRO D 2 209 ? 206.736 182.362 290.953 1.00 62.37  ? 448 PRO E O   1 
ATOM   7415 C CB  . PRO D 2 209 ? 207.264 180.347 293.326 1.00 51.78  ? 448 PRO E CB  1 
ATOM   7416 C CG  . PRO D 2 209 ? 206.901 180.787 294.705 1.00 54.51  ? 448 PRO E CG  1 
ATOM   7417 C CD  . PRO D 2 209 ? 206.712 182.266 294.613 1.00 52.33  ? 448 PRO E CD  1 
ATOM   7418 N N   . ARG D 2 210 ? 208.644 181.291 290.411 1.00 45.85  ? 449 ARG E N   1 
ATOM   7419 C CA  . ARG D 2 210 ? 208.510 181.580 288.990 1.00 45.46  ? 449 ARG E CA  1 
ATOM   7420 C C   . ARG D 2 210 ? 207.214 181.004 288.437 1.00 49.35  ? 449 ARG E C   1 
ATOM   7421 O O   . ARG D 2 210 ? 206.890 179.835 288.660 1.00 50.77  ? 449 ARG E O   1 
ATOM   7422 C CB  . ARG D 2 210 ? 209.709 181.026 288.224 1.00 44.84  ? 449 ARG E CB  1 
ATOM   7423 C CG  . ARG D 2 210 ? 211.023 181.682 288.594 1.00 41.82  ? 449 ARG E CG  1 
ATOM   7424 C CD  . ARG D 2 210 ? 212.197 180.971 287.954 1.00 43.68  ? 449 ARG E CD  1 
ATOM   7425 N NE  . ARG D 2 210 ? 213.399 181.071 288.772 1.00 44.10  ? 449 ARG E NE  1 
ATOM   7426 C CZ  . ARG D 2 210 ? 214.371 181.949 288.569 1.00 46.89  ? 449 ARG E CZ  1 
ATOM   7427 N NH1 . ARG D 2 210 ? 214.318 182.818 287.574 1.00 50.46  ? 449 ARG E NH1 1 
ATOM   7428 N NH2 . ARG D 2 210 ? 215.423 181.951 289.381 1.00 41.81  ? 449 ARG E NH2 1 
ATOM   7429 N N   . SER D 2 211 ? 206.474 181.839 287.715 1.00 49.21  ? 450 SER E N   1 
ATOM   7430 C CA  . SER D 2 211 ? 205.238 181.425 287.062 1.00 44.74  ? 450 SER E CA  1 
ATOM   7431 C C   . SER D 2 211 ? 205.104 182.230 285.782 1.00 50.46  ? 450 SER E C   1 
ATOM   7432 O O   . SER D 2 211 ? 205.022 183.460 285.837 1.00 57.42  ? 450 SER E O   1 
ATOM   7433 C CB  . SER D 2 211 ? 204.029 181.645 287.969 1.00 46.58  ? 450 SER E CB  1 
ATOM   7434 O OG  . SER D 2 211 ? 204.160 182.848 288.704 1.00 52.24  ? 450 SER E OG  1 
ATOM   7435 N N   . ALA D 2 212 ? 205.095 181.543 284.643 1.00 49.73  ? 451 ALA E N   1 
ATOM   7436 C CA  . ALA D 2 212 ? 205.038 182.224 283.357 1.00 49.88  ? 451 ALA E CA  1 
ATOM   7437 C C   . ALA D 2 212 ? 203.803 183.111 283.279 1.00 54.01  ? 451 ALA E C   1 
ATOM   7438 O O   . ALA D 2 212 ? 202.697 182.690 283.626 1.00 57.74  ? 451 ALA E O   1 
ATOM   7439 C CB  . ALA D 2 212 ? 205.035 181.205 282.219 1.00 43.44  ? 451 ALA E CB  1 
ATOM   7440 N N   . PHE D 2 213 ? 203.998 184.348 282.827 1.00 56.58  ? 452 PHE E N   1 
ATOM   7441 C CA  . PHE D 2 213 ? 202.898 185.304 282.788 1.00 56.99  ? 452 PHE E CA  1 
ATOM   7442 C C   . PHE D 2 213 ? 202.027 185.097 281.555 1.00 56.47  ? 452 PHE E C   1 
ATOM   7443 O O   . PHE D 2 213 ? 200.831 184.809 281.670 1.00 59.41  ? 452 PHE E O   1 
ATOM   7444 C CB  . PHE D 2 213 ? 203.442 186.735 282.830 1.00 65.01  ? 452 PHE E CB  1 
ATOM   7445 C CG  . PHE D 2 213 ? 204.418 186.983 283.946 1.00 63.89  ? 452 PHE E CG  1 
ATOM   7446 C CD1 . PHE D 2 213 ? 203.974 187.354 285.202 1.00 59.88  ? 452 PHE E CD1 1 
ATOM   7447 C CD2 . PHE D 2 213 ? 205.779 186.853 283.735 1.00 60.08  ? 452 PHE E CD2 1 
ATOM   7448 C CE1 . PHE D 2 213 ? 204.866 187.585 286.226 1.00 58.31  ? 452 PHE E CE1 1 
ATOM   7449 C CE2 . PHE D 2 213 ? 206.674 187.084 284.755 1.00 54.51  ? 452 PHE E CE2 1 
ATOM   7450 C CZ  . PHE D 2 213 ? 206.218 187.450 286.002 1.00 53.59  ? 452 PHE E CZ  1 
ATOM   7451 N N   . SER D 2 214 ? 202.612 185.261 280.366 1.00 56.39  ? 453 SER E N   1 
ATOM   7452 C CA  . SER D 2 214 ? 201.914 185.115 279.090 1.00 63.84  ? 453 SER E CA  1 
ATOM   7453 C C   . SER D 2 214 ? 200.771 186.116 278.959 1.00 66.15  ? 453 SER E C   1 
ATOM   7454 O O   . SER D 2 214 ? 199.979 186.049 278.013 1.00 75.16  ? 453 SER E O   1 
ATOM   7455 C CB  . SER D 2 214 ? 201.393 183.686 278.913 1.00 66.87  ? 453 SER E CB  1 
ATOM   7456 O OG  . SER D 2 214 ? 200.250 183.454 279.719 1.00 66.55  ? 453 SER E OG  1 
ATOM   7457 N N   . VAL D 2 215 ? 200.677 187.044 279.908 1.00 49.41  ? 454 VAL E N   1 
ATOM   7458 C CA  . VAL D 2 215 ? 199.683 188.117 279.870 1.00 48.66  ? 454 VAL E CA  1 
ATOM   7459 C C   . VAL D 2 215 ? 200.358 189.421 280.241 1.00 52.05  ? 454 VAL E C   1 
ATOM   7460 O O   . VAL D 2 215 ? 201.207 189.470 281.141 1.00 58.58  ? 454 VAL E O   1 
ATOM   7461 C CB  . VAL D 2 215 ? 198.509 187.840 280.839 1.00 51.14  ? 454 VAL E CB  1 
ATOM   7462 C CG1 . VAL D 2 215 ? 197.515 188.990 280.862 1.00 53.76  ? 454 VAL E CG1 1 
ATOM   7463 C CG2 . VAL D 2 215 ? 197.802 186.548 280.462 1.00 49.04  ? 454 VAL E CG2 1 
ATOM   7464 N N   . PRO D 2 216 ? 200.028 190.499 279.528 1.00 48.89  ? 455 PRO E N   1 
ATOM   7465 C CA  . PRO D 2 216 ? 200.614 191.807 279.861 1.00 48.71  ? 455 PRO E CA  1 
ATOM   7466 C C   . PRO D 2 216 ? 200.396 192.156 281.324 1.00 49.30  ? 455 PRO E C   1 
ATOM   7467 O O   . PRO D 2 216 ? 199.267 192.338 281.780 1.00 55.65  ? 455 PRO E O   1 
ATOM   7468 C CB  . PRO D 2 216 ? 199.874 192.768 278.924 1.00 45.48  ? 455 PRO E CB  1 
ATOM   7469 C CG  . PRO D 2 216 ? 199.515 191.925 277.758 1.00 45.84  ? 455 PRO E CG  1 
ATOM   7470 C CD  . PRO D 2 216 ? 199.200 190.566 278.312 1.00 54.23  ? 455 PRO E CD  1 
ATOM   7471 N N   . VAL D 2 217 ? 201.495 192.244 282.060 1.00 44.21  ? 456 VAL E N   1 
ATOM   7472 C CA  . VAL D 2 217 ? 201.446 192.459 283.497 1.00 44.24  ? 456 VAL E CA  1 
ATOM   7473 C C   . VAL D 2 217 ? 201.437 193.953 283.789 1.00 45.58  ? 456 VAL E C   1 
ATOM   7474 O O   . VAL D 2 217 ? 201.805 194.783 282.955 1.00 46.63  ? 456 VAL E O   1 
ATOM   7475 C CB  . VAL D 2 217 ? 202.617 191.759 284.209 1.00 44.94  ? 456 VAL E CB  1 
ATOM   7476 C CG1 . VAL D 2 217 ? 202.300 190.294 284.407 1.00 41.94  ? 456 VAL E CG1 1 
ATOM   7477 C CG2 . VAL D 2 217 ? 203.890 191.920 283.402 1.00 45.87  ? 456 VAL E CG2 1 
ATOM   7478 N N   . ARG D 2 218 ? 201.006 194.300 285.000 1.00 44.02  ? 457 ARG E N   1 
ATOM   7479 C CA  . ARG D 2 218 ? 200.809 195.684 285.345 1.00 43.12  ? 457 ARG E CA  1 
ATOM   7480 C C   . ARG D 2 218 ? 201.011 195.886 286.841 1.00 50.44  ? 457 ARG E C   1 
ATOM   7481 O O   . ARG D 2 218 ? 200.575 195.034 287.633 1.00 57.36  ? 457 ARG E O   1 
ATOM   7482 C CB  . ARG D 2 218 ? 199.408 196.126 284.924 1.00 39.01  ? 457 ARG E CB  1 
ATOM   7483 C CG  . ARG D 2 218 ? 198.782 197.199 285.779 1.00 44.28  ? 457 ARG E CG  1 
ATOM   7484 C CD  . ARG D 2 218 ? 197.490 197.677 285.149 1.00 48.84  ? 457 ARG E CD  1 
ATOM   7485 N NE  . ARG D 2 218 ? 197.717 198.238 283.824 1.00 41.16  ? 457 ARG E NE  1 
ATOM   7486 C CZ  . ARG D 2 218 ? 196.783 198.826 283.091 1.00 41.92  ? 457 ARG E CZ  1 
ATOM   7487 N NH1 . ARG D 2 218 ? 195.542 198.953 283.527 1.00 45.14  ? 457 ARG E NH1 1 
ATOM   7488 N NH2 . ARG D 2 218 ? 197.104 199.300 281.891 1.00 42.32  ? 457 ARG E NH2 1 
ATOM   7489 N N   . PRO D 2 219 ? 201.685 196.959 287.252 1.00 41.73  ? 458 PRO E N   1 
ATOM   7490 C CA  . PRO D 2 219 ? 201.849 197.221 288.687 1.00 33.53  ? 458 PRO E CA  1 
ATOM   7491 C C   . PRO D 2 219 ? 200.508 197.421 289.377 1.00 33.48  ? 458 PRO E C   1 
ATOM   7492 O O   . PRO D 2 219 ? 199.574 197.993 288.813 1.00 45.32  ? 458 PRO E O   1 
ATOM   7493 C CB  . PRO D 2 219 ? 202.693 198.499 288.714 1.00 40.17  ? 458 PRO E CB  1 
ATOM   7494 C CG  . PRO D 2 219 ? 203.441 198.470 287.424 1.00 37.49  ? 458 PRO E CG  1 
ATOM   7495 C CD  . PRO D 2 219 ? 202.491 197.874 286.429 1.00 39.21  ? 458 PRO E CD  1 
ATOM   7496 N N   . PHE D 2 220 ? 200.428 196.952 290.618 1.00 42.55  ? 459 PHE E N   1 
ATOM   7497 C CA  . PHE D 2 220 ? 199.195 196.924 291.390 1.00 44.39  ? 459 PHE E CA  1 
ATOM   7498 C C   . PHE D 2 220 ? 199.496 197.387 292.808 1.00 52.62  ? 459 PHE E C   1 
ATOM   7499 O O   . PHE D 2 220 ? 200.426 196.877 293.449 1.00 59.48  ? 459 PHE E O   1 
ATOM   7500 C CB  . PHE D 2 220 ? 198.601 195.510 291.379 1.00 51.66  ? 459 PHE E CB  1 
ATOM   7501 C CG  . PHE D 2 220 ? 197.774 195.177 292.584 1.00 49.67  ? 459 PHE E CG  1 
ATOM   7502 C CD1 . PHE D 2 220 ? 196.459 195.592 292.672 1.00 52.72  ? 459 PHE E CD1 1 
ATOM   7503 C CD2 . PHE D 2 220 ? 198.301 194.426 293.616 1.00 45.80  ? 459 PHE E CD2 1 
ATOM   7504 C CE1 . PHE D 2 220 ? 195.693 195.276 293.774 1.00 50.19  ? 459 PHE E CE1 1 
ATOM   7505 C CE2 . PHE D 2 220 ? 197.538 194.112 294.720 1.00 46.62  ? 459 PHE E CE2 1 
ATOM   7506 C CZ  . PHE D 2 220 ? 196.233 194.539 294.798 1.00 46.77  ? 459 PHE E CZ  1 
ATOM   7507 N N   . PHE D 2 221 ? 198.712 198.351 293.296 1.00 50.29  ? 460 PHE E N   1 
ATOM   7508 C CA  . PHE D 2 221 ? 198.928 198.945 294.607 1.00 55.70  ? 460 PHE E CA  1 
ATOM   7509 C C   . PHE D 2 221 ? 197.628 198.875 295.388 1.00 57.04  ? 460 PHE E C   1 
ATOM   7510 O O   . PHE D 2 221 ? 196.549 198.934 294.798 1.00 54.63  ? 460 PHE E O   1 
ATOM   7511 C CB  . PHE D 2 221 ? 199.396 200.396 294.483 1.00 47.18  ? 460 PHE E CB  1 
ATOM   7512 C CG  . PHE D 2 221 ? 200.683 200.551 293.733 1.00 50.92  ? 460 PHE E CG  1 
ATOM   7513 C CD1 . PHE D 2 221 ? 201.832 199.918 294.167 1.00 49.76  ? 460 PHE E CD1 1 
ATOM   7514 C CD2 . PHE D 2 221 ? 200.742 201.323 292.589 1.00 58.91  ? 460 PHE E CD2 1 
ATOM   7515 C CE1 . PHE D 2 221 ? 203.015 200.055 293.479 1.00 48.32  ? 460 PHE E CE1 1 
ATOM   7516 C CE2 . PHE D 2 221 ? 201.925 201.462 291.895 1.00 60.32  ? 460 PHE E CE2 1 
ATOM   7517 C CZ  . PHE D 2 221 ? 203.062 200.827 292.341 1.00 54.68  ? 460 PHE E CZ  1 
ATOM   7518 N N   . ARG D 2 222 ? 197.731 198.749 296.707 1.00 76.46  ? 461 ARG E N   1 
ATOM   7519 C CA  . ARG D 2 222 ? 196.566 198.600 297.564 1.00 75.76  ? 461 ARG E CA  1 
ATOM   7520 C C   . ARG D 2 222 ? 196.848 199.265 298.901 1.00 85.44  ? 461 ARG E C   1 
ATOM   7521 O O   . ARG D 2 222 ? 197.826 198.930 299.576 1.00 86.03  ? 461 ARG E O   1 
ATOM   7522 C CB  . ARG D 2 222 ? 196.219 197.119 297.761 1.00 74.38  ? 461 ARG E CB  1 
ATOM   7523 C CG  . ARG D 2 222 ? 195.323 196.824 298.949 1.00 75.79  ? 461 ARG E CG  1 
ATOM   7524 C CD  . ARG D 2 222 ? 194.862 195.376 298.922 1.00 72.71  ? 461 ARG E CD  1 
ATOM   7525 N NE  . ARG D 2 222 ? 194.068 195.033 300.094 1.00 72.76  ? 461 ARG E NE  1 
ATOM   7526 C CZ  . ARG D 2 222 ? 194.572 194.539 301.216 1.00 77.88  ? 461 ARG E CZ  1 
ATOM   7527 N NH1 . ARG D 2 222 ? 195.868 194.312 301.350 1.00 81.44  ? 461 ARG E NH1 1 
ATOM   7528 N NH2 . ARG D 2 222 ? 193.755 194.264 302.228 1.00 77.29  ? 461 ARG E NH2 1 
ATOM   7529 N N   . LEU D 2 223 ? 195.991 200.206 299.279 1.00 95.85  ? 462 LEU E N   1 
ATOM   7530 C CA  . LEU D 2 223 ? 196.184 200.993 300.485 1.00 88.94  ? 462 LEU E CA  1 
ATOM   7531 C C   . LEU D 2 223 ? 195.116 200.648 301.513 1.00 90.89  ? 462 LEU E C   1 
ATOM   7532 O O   . LEU D 2 223 ? 193.916 200.753 301.247 1.00 91.42  ? 462 LEU E O   1 
ATOM   7533 C CB  . LEU D 2 223 ? 196.146 202.488 300.175 1.00 84.96  ? 462 LEU E CB  1 
ATOM   7534 C CG  . LEU D 2 223 ? 196.220 203.396 301.396 1.00 90.14  ? 462 LEU E CG  1 
ATOM   7535 C CD1 . LEU D 2 223 ? 197.663 203.729 301.694 1.00 92.86  ? 462 LEU E CD1 1 
ATOM   7536 C CD2 . LEU D 2 223 ? 195.423 204.656 301.159 1.00 90.47  ? 462 LEU E CD2 1 
ATOM   7537 N N   . GLY D 2 224 ? 195.566 200.244 302.695 1.00 94.84  ? 463 GLY E N   1 
ATOM   7538 C CA  . GLY D 2 224 ? 194.685 199.848 303.771 1.00 90.54  ? 463 GLY E CA  1 
ATOM   7539 C C   . GLY D 2 224 ? 193.990 201.028 304.416 1.00 91.84  ? 463 GLY E C   1 
ATOM   7540 O O   . GLY D 2 224 ? 193.917 202.127 303.861 1.00 91.42  ? 463 GLY E O   1 
ATOM   7541 N N   . CYS D 2 225 ? 193.472 200.788 305.620 1.00 114.46 ? 464 CYS E N   1 
ATOM   7542 C CA  . CYS D 2 225 ? 192.748 201.812 306.371 1.00 117.61 ? 464 CYS E CA  1 
ATOM   7543 C C   . CYS D 2 225 ? 193.727 202.781 307.039 1.00 113.81 ? 464 CYS E C   1 
ATOM   7544 O O   . CYS D 2 225 ? 193.781 202.928 308.259 1.00 116.24 ? 464 CYS E O   1 
ATOM   7545 C CB  . CYS D 2 225 ? 191.825 201.160 307.393 1.00 119.29 ? 464 CYS E CB  1 
ATOM   7546 S SG  . CYS D 2 225 ? 190.472 200.203 306.671 1.00 123.89 ? 464 CYS E SG  1 
ATOM   7547 N N   . GLU D 2 226 ? 194.512 203.452 306.200 1.00 106.32 ? 465 GLU E N   1 
ATOM   7548 C CA  . GLU D 2 226 ? 195.473 204.449 306.657 1.00 113.94 ? 465 GLU E CA  1 
ATOM   7549 C C   . GLU D 2 226 ? 195.404 205.644 305.721 1.00 113.60 ? 465 GLU E C   1 
ATOM   7550 O O   . GLU D 2 226 ? 195.719 205.521 304.534 1.00 114.41 ? 465 GLU E O   1 
ATOM   7551 C CB  . GLU D 2 226 ? 196.892 203.874 306.700 1.00 111.62 ? 465 GLU E CB  1 
ATOM   7552 C CG  . GLU D 2 226 ? 197.910 204.789 307.357 1.00 110.38 ? 465 GLU E CG  1 
ATOM   7553 C CD  . GLU D 2 226 ? 197.760 204.840 308.864 1.00 112.73 ? 465 GLU E CD  1 
ATOM   7554 O OE1 . GLU D 2 226 ? 197.239 203.864 309.443 1.00 112.66 ? 465 GLU E OE1 1 
ATOM   7555 O OE2 . GLU D 2 226 ? 198.164 205.855 309.470 1.00 114.53 ? 465 GLU E OE2 1 
ATOM   7556 N N   . ASP D 2 227 ? 194.998 206.799 306.255 1.00 102.97 ? 466 ASP E N   1 
ATOM   7557 C CA  . ASP D 2 227 ? 194.806 207.988 305.432 1.00 100.74 ? 466 ASP E CA  1 
ATOM   7558 C C   . ASP D 2 227 ? 196.110 208.555 304.889 1.00 101.41 ? 466 ASP E C   1 
ATOM   7559 O O   . ASP D 2 227 ? 196.063 209.430 304.019 1.00 104.66 ? 466 ASP E O   1 
ATOM   7560 C CB  . ASP D 2 227 ? 194.070 209.066 306.228 1.00 99.92  ? 466 ASP E CB  1 
ATOM   7561 C CG  . ASP D 2 227 ? 193.070 209.832 305.384 1.00 99.54  ? 466 ASP E CG  1 
ATOM   7562 O OD1 . ASP D 2 227 ? 193.487 210.477 304.401 1.00 99.42  ? 466 ASP E OD1 1 
ATOM   7563 O OD2 . ASP D 2 227 ? 191.862 209.784 305.698 1.00 100.44 ? 466 ASP E OD2 1 
ATOM   7564 N N   . SER D 2 228 ? 197.255 208.095 305.376 1.00 87.31  ? 467 SER E N   1 
ATOM   7565 C CA  . SER D 2 228 ? 198.524 208.560 304.839 1.00 86.25  ? 467 SER E CA  1 
ATOM   7566 C C   . SER D 2 228 ? 198.648 208.139 303.378 1.00 87.17  ? 467 SER E C   1 
ATOM   7567 O O   . SER D 2 228 ? 198.347 206.985 303.043 1.00 85.98  ? 467 SER E O   1 
ATOM   7568 C CB  . SER D 2 228 ? 199.689 208.004 305.652 1.00 85.26  ? 467 SER E CB  1 
ATOM   7569 O OG  . SER D 2 228 ? 199.671 208.511 306.974 1.00 84.21  ? 467 SER E OG  1 
ATOM   7570 N N   . PRO D 2 229 ? 199.061 209.031 302.486 1.00 81.59  ? 468 PRO E N   1 
ATOM   7571 C CA  . PRO D 2 229 ? 199.149 208.677 301.070 1.00 81.60  ? 468 PRO E CA  1 
ATOM   7572 C C   . PRO D 2 229 ? 200.405 207.877 300.764 1.00 81.82  ? 468 PRO E C   1 
ATOM   7573 O O   . PRO D 2 229 ? 201.392 207.904 301.500 1.00 86.66  ? 468 PRO E O   1 
ATOM   7574 C CB  . PRO D 2 229 ? 199.184 210.039 300.373 1.00 82.67  ? 468 PRO E CB  1 
ATOM   7575 C CG  . PRO D 2 229 ? 199.855 210.929 301.363 1.00 82.01  ? 468 PRO E CG  1 
ATOM   7576 C CD  . PRO D 2 229 ? 199.487 210.418 302.737 1.00 82.84  ? 468 PRO E CD  1 
ATOM   7577 N N   . ILE D 2 230 ? 200.351 207.155 299.648 1.00 68.20  ? 469 ILE E N   1 
ATOM   7578 C CA  . ILE D 2 230 ? 201.499 206.415 299.140 1.00 73.49  ? 469 ILE E CA  1 
ATOM   7579 C C   . ILE D 2 230 ? 202.097 207.192 297.977 1.00 77.98  ? 469 ILE E C   1 
ATOM   7580 O O   . ILE D 2 230 ? 201.379 207.611 297.059 1.00 75.22  ? 469 ILE E O   1 
ATOM   7581 C CB  . ILE D 2 230 ? 201.115 204.985 298.717 1.00 70.64  ? 469 ILE E CB  1 
ATOM   7582 C CG1 . ILE D 2 230 ? 199.901 204.989 297.790 1.00 73.35  ? 469 ILE E CG1 1 
ATOM   7583 C CG2 . ILE D 2 230 ? 200.854 204.120 299.937 1.00 72.31  ? 469 ILE E CG2 1 
ATOM   7584 C CD1 . ILE D 2 230 ? 199.612 203.641 297.174 1.00 75.21  ? 469 ILE E CD1 1 
ATOM   7585 N N   . PHE D 2 231 ? 203.407 207.407 298.028 1.00 69.70  ? 470 PHE E N   1 
ATOM   7586 C CA  . PHE D 2 231 ? 204.139 208.104 296.982 1.00 61.52  ? 470 PHE E CA  1 
ATOM   7587 C C   . PHE D 2 231 ? 204.950 207.097 296.184 1.00 58.86  ? 470 PHE E C   1 
ATOM   7588 O O   . PHE D 2 231 ? 205.685 206.289 296.762 1.00 59.54  ? 470 PHE E O   1 
ATOM   7589 C CB  . PHE D 2 231 ? 205.072 209.165 297.568 1.00 67.69  ? 470 PHE E CB  1 
ATOM   7590 C CG  . PHE D 2 231 ? 204.363 210.326 298.202 1.00 67.53  ? 470 PHE E CG  1 
ATOM   7591 C CD1 . PHE D 2 231 ? 203.037 210.589 297.919 1.00 65.66  ? 470 PHE E CD1 1 
ATOM   7592 C CD2 . PHE D 2 231 ? 205.033 211.156 299.085 1.00 63.97  ? 470 PHE E CD2 1 
ATOM   7593 C CE1 . PHE D 2 231 ? 202.392 211.659 298.504 1.00 69.68  ? 470 PHE E CE1 1 
ATOM   7594 C CE2 . PHE D 2 231 ? 204.394 212.225 299.672 1.00 65.03  ? 470 PHE E CE2 1 
ATOM   7595 C CZ  . PHE D 2 231 ? 203.072 212.477 299.381 1.00 69.68  ? 470 PHE E CZ  1 
ATOM   7596 N N   . ILE D 2 232 ? 204.815 207.146 294.865 1.00 36.76  ? 471 ILE E N   1 
ATOM   7597 C CA  . ILE D 2 232 ? 205.679 206.405 293.958 1.00 35.45  ? 471 ILE E CA  1 
ATOM   7598 C C   . ILE D 2 232 ? 206.765 207.359 293.489 1.00 42.86  ? 471 ILE E C   1 
ATOM   7599 O O   . ILE D 2 232 ? 206.468 208.403 292.897 1.00 56.90  ? 471 ILE E O   1 
ATOM   7600 C CB  . ILE D 2 232 ? 204.893 205.831 292.772 1.00 39.38  ? 471 ILE E CB  1 
ATOM   7601 C CG1 . ILE D 2 232 ? 203.654 205.094 293.273 1.00 43.52  ? 471 ILE E CG1 1 
ATOM   7602 C CG2 . ILE D 2 232 ? 205.775 204.912 291.950 1.00 45.68  ? 471 ILE E CG2 1 
ATOM   7603 C CD1 . ILE D 2 232 ? 202.472 205.215 292.357 1.00 43.98  ? 471 ILE E CD1 1 
ATOM   7604 N N   . CYS D 2 233 ? 208.014 207.014 293.762 1.00 48.21  ? 472 CYS E N   1 
ATOM   7605 C CA  . CYS D 2 233 ? 209.117 207.919 293.478 1.00 48.24  ? 472 CYS E CA  1 
ATOM   7606 C C   . CYS D 2 233 ? 209.226 208.166 291.979 1.00 54.13  ? 472 CYS E C   1 
ATOM   7607 O O   . CYS D 2 233 ? 209.349 207.202 291.208 1.00 62.24  ? 472 CYS E O   1 
ATOM   7608 C CB  . CYS D 2 233 ? 210.425 207.347 294.013 1.00 45.85  ? 472 CYS E CB  1 
ATOM   7609 S SG  . CYS D 2 233 ? 210.594 207.447 295.802 1.00 70.33  ? 472 CYS E SG  1 
ATOM   7610 N N   . PRO D 2 234 ? 209.178 209.414 291.524 1.00 35.41  ? 473 PRO E N   1 
ATOM   7611 C CA  . PRO D 2 234 ? 209.355 209.681 290.096 1.00 34.12  ? 473 PRO E CA  1 
ATOM   7612 C C   . PRO D 2 234 ? 210.773 209.361 289.658 1.00 38.90  ? 473 PRO E C   1 
ATOM   7613 O O   . PRO D 2 234 ? 211.722 209.435 290.442 1.00 43.23  ? 473 PRO E O   1 
ATOM   7614 C CB  . PRO D 2 234 ? 209.057 211.181 289.968 1.00 36.59  ? 473 PRO E CB  1 
ATOM   7615 C CG  . PRO D 2 234 ? 208.451 211.589 291.281 1.00 37.37  ? 473 PRO E CG  1 
ATOM   7616 C CD  . PRO D 2 234 ? 208.999 210.650 292.298 1.00 32.17  ? 473 PRO E CD  1 
ATOM   7617 N N   . ALA D 2 235 ? 210.909 208.996 288.387 1.00 27.48  ? 474 ALA E N   1 
ATOM   7618 C CA  . ALA D 2 235 ? 212.221 208.679 287.852 1.00 29.57  ? 474 ALA E CA  1 
ATOM   7619 C C   . ALA D 2 235 ? 213.104 209.922 287.840 1.00 36.78  ? 474 ALA E C   1 
ATOM   7620 O O   . ALA D 2 235 ? 212.636 211.055 287.977 1.00 40.33  ? 474 ALA E O   1 
ATOM   7621 C CB  . ALA D 2 235 ? 212.102 208.100 286.444 1.00 32.48  ? 474 ALA E CB  1 
ATOM   7622 N N   . LEU D 2 236 ? 214.402 209.698 287.675 1.00 41.75  ? 475 LEU E N   1 
ATOM   7623 C CA  . LEU D 2 236 ? 215.361 210.798 287.651 1.00 40.87  ? 475 LEU E CA  1 
ATOM   7624 C C   . LEU D 2 236 ? 215.161 211.582 286.363 1.00 45.86  ? 475 LEU E C   1 
ATOM   7625 O O   . LEU D 2 236 ? 215.661 211.204 285.303 1.00 43.27  ? 475 LEU E O   1 
ATOM   7626 C CB  . LEU D 2 236 ? 216.783 210.264 287.761 1.00 37.56  ? 475 LEU E CB  1 
ATOM   7627 C CG  . LEU D 2 236 ? 217.056 209.322 288.931 1.00 36.43  ? 475 LEU E CG  1 
ATOM   7628 C CD1 . LEU D 2 236 ? 218.532 208.999 289.012 1.00 38.65  ? 475 LEU E CD1 1 
ATOM   7629 C CD2 . LEU D 2 236 ? 216.569 209.933 290.229 1.00 33.98  ? 475 LEU E CD2 1 
ATOM   7630 N N   . THR D 2 237 ? 214.417 212.685 286.452 1.00 49.85  ? 476 THR E N   1 
ATOM   7631 C CA  . THR D 2 237 ? 214.148 213.499 285.274 1.00 43.96  ? 476 THR E CA  1 
ATOM   7632 C C   . THR D 2 237 ? 215.358 214.332 284.869 1.00 46.64  ? 476 THR E C   1 
ATOM   7633 O O   . THR D 2 237 ? 215.551 214.599 283.679 1.00 52.66  ? 476 THR E O   1 
ATOM   7634 C CB  . THR D 2 237 ? 212.942 214.407 285.531 1.00 42.66  ? 476 THR E CB  1 
ATOM   7635 O OG1 . THR D 2 237 ? 211.868 213.634 286.079 1.00 37.55  ? 476 THR E OG1 1 
ATOM   7636 C CG2 . THR D 2 237 ? 212.471 215.051 284.239 1.00 48.10  ? 476 THR E CG2 1 
ATOM   7637 N N   . GLY D 2 238 ? 216.184 214.734 285.832 1.00 43.57  ? 477 GLY E N   1 
ATOM   7638 C CA  . GLY D 2 238 ? 217.337 215.563 285.544 1.00 39.35  ? 477 GLY E CA  1 
ATOM   7639 C C   . GLY D 2 238 ? 216.993 217.036 285.542 1.00 45.85  ? 477 GLY E C   1 
ATOM   7640 O O   . GLY D 2 238 ? 216.178 217.488 286.351 1.00 54.76  ? 477 GLY E O   1 
ATOM   7641 N N   . ALA D 2 239 ? 217.608 217.801 284.640 1.00 39.00  ? 478 ALA E N   1 
ATOM   7642 C CA  . ALA D 2 239 ? 217.293 219.212 284.466 1.00 41.89  ? 478 ALA E CA  1 
ATOM   7643 C C   . ALA D 2 239 ? 216.337 219.445 283.304 1.00 46.87  ? 478 ALA E C   1 
ATOM   7644 O O   . ALA D 2 239 ? 216.406 220.483 282.638 1.00 52.91  ? 478 ALA E O   1 
ATOM   7645 C CB  . ALA D 2 239 ? 218.571 220.024 284.272 1.00 47.19  ? 478 ALA E CB  1 
ATOM   7646 N N   . ASN D 2 240 ? 215.448 218.493 283.044 1.00 44.04  ? 479 ASN E N   1 
ATOM   7647 C CA  . ASN D 2 240 ? 214.562 218.584 281.894 1.00 47.03  ? 479 ASN E CA  1 
ATOM   7648 C C   . ASN D 2 240 ? 213.484 219.634 282.127 1.00 53.43  ? 479 ASN E C   1 
ATOM   7649 O O   . ASN D 2 240 ? 212.898 219.718 283.209 1.00 50.66  ? 479 ASN E O   1 
ATOM   7650 C CB  . ASN D 2 240 ? 213.931 217.221 281.613 1.00 45.43  ? 479 ASN E CB  1 
ATOM   7651 C CG  . ASN D 2 240 ? 212.616 217.324 280.874 1.00 54.05  ? 479 ASN E CG  1 
ATOM   7652 O OD1 . ASN D 2 240 ? 211.555 217.451 281.484 1.00 58.62  ? 479 ASN E OD1 1 
ATOM   7653 N ND2 . ASN D 2 240 ? 212.677 217.259 279.550 1.00 53.88  ? 479 ASN E ND2 1 
ATOM   7654 N N   . GLY D 2 241 ? 213.227 220.439 281.097 1.00 48.20  ? 480 GLY E N   1 
ATOM   7655 C CA  . GLY D 2 241 ? 212.184 221.443 281.164 1.00 35.18  ? 480 GLY E CA  1 
ATOM   7656 C C   . GLY D 2 241 ? 212.512 222.651 282.006 1.00 39.55  ? 480 GLY E C   1 
ATOM   7657 O O   . GLY D 2 241 ? 211.598 223.345 282.454 1.00 46.68  ? 480 GLY E O   1 
ATOM   7658 N N   . VAL D 2 242 ? 213.795 222.924 282.238 1.00 46.32  ? 481 VAL E N   1 
ATOM   7659 C CA  . VAL D 2 242 ? 214.220 224.055 283.048 1.00 48.48  ? 481 VAL E CA  1 
ATOM   7660 C C   . VAL D 2 242 ? 215.348 224.779 282.326 1.00 45.17  ? 481 VAL E C   1 
ATOM   7661 O O   . VAL D 2 242 ? 216.047 224.212 281.483 1.00 53.05  ? 481 VAL E O   1 
ATOM   7662 C CB  . VAL D 2 242 ? 214.662 223.620 284.464 1.00 46.67  ? 481 VAL E CB  1 
ATOM   7663 C CG1 . VAL D 2 242 ? 216.124 223.209 284.475 1.00 45.09  ? 481 VAL E CG1 1 
ATOM   7664 C CG2 . VAL D 2 242 ? 214.401 224.726 285.472 1.00 47.66  ? 481 VAL E CG2 1 
ATOM   7665 N N   . THR D 2 243 ? 215.510 226.056 282.659 1.00 38.15  ? 482 THR E N   1 
ATOM   7666 C CA  . THR D 2 243 ? 216.577 226.873 282.100 1.00 39.63  ? 482 THR E CA  1 
ATOM   7667 C C   . THR D 2 243 ? 217.839 226.698 282.931 1.00 48.01  ? 482 THR E C   1 
ATOM   7668 O O   . THR D 2 243 ? 217.843 226.986 284.131 1.00 55.06  ? 482 THR E O   1 
ATOM   7669 C CB  . THR D 2 243 ? 216.179 228.347 282.069 1.00 45.91  ? 482 THR E CB  1 
ATOM   7670 O OG1 . THR D 2 243 ? 215.026 228.517 281.240 1.00 47.78  ? 482 THR E OG1 1 
ATOM   7671 C CG2 . THR D 2 243 ? 217.314 229.186 281.514 1.00 47.24  ? 482 THR E CG2 1 
ATOM   7672 N N   . VAL D 2 244 ? 218.904 226.233 282.293 1.00 40.84  ? 483 VAL E N   1 
ATOM   7673 C CA  . VAL D 2 244 ? 220.174 225.973 282.963 1.00 41.67  ? 483 VAL E CA  1 
ATOM   7674 C C   . VAL D 2 244 ? 221.040 227.222 282.844 1.00 50.26  ? 483 VAL E C   1 
ATOM   7675 O O   . VAL D 2 244 ? 221.318 227.661 281.718 1.00 51.84  ? 483 VAL E O   1 
ATOM   7676 C CB  . VAL D 2 244 ? 220.886 224.751 282.366 1.00 37.46  ? 483 VAL E CB  1 
ATOM   7677 C CG1 . VAL D 2 244 ? 222.073 224.360 283.225 1.00 38.34  ? 483 VAL E CG1 1 
ATOM   7678 C CG2 . VAL D 2 244 ? 219.916 223.595 282.248 1.00 38.49  ? 483 VAL E CG2 1 
ATOM   7679 N N   . PRO D 2 245 ? 221.473 227.823 283.953 1.00 49.11  ? 484 PRO E N   1 
ATOM   7680 C CA  . PRO D 2 245 ? 222.416 228.947 283.870 1.00 42.02  ? 484 PRO E CA  1 
ATOM   7681 C C   . PRO D 2 245 ? 223.806 228.518 283.424 1.00 45.99  ? 484 PRO E C   1 
ATOM   7682 O O   . PRO D 2 245 ? 224.038 227.344 283.121 1.00 55.29  ? 484 PRO E O   1 
ATOM   7683 C CB  . PRO D 2 245 ? 222.438 229.493 285.303 1.00 41.98  ? 484 PRO E CB  1 
ATOM   7684 C CG  . PRO D 2 245 ? 221.187 228.981 285.934 1.00 42.08  ? 484 PRO E CG  1 
ATOM   7685 C CD  . PRO D 2 245 ? 220.945 227.646 285.314 1.00 44.70  ? 484 PRO E CD  1 
ATOM   7686 N N   . GLU D 2 246 ? 224.739 229.467 283.381 1.00 45.12  ? 485 GLU E N   1 
ATOM   7687 C CA  . GLU D 2 246 ? 226.110 229.169 282.988 1.00 47.64  ? 485 GLU E CA  1 
ATOM   7688 C C   . GLU D 2 246 ? 226.978 228.737 284.160 1.00 50.58  ? 485 GLU E C   1 
ATOM   7689 O O   . GLU D 2 246 ? 227.998 228.070 283.952 1.00 54.88  ? 485 GLU E O   1 
ATOM   7690 C CB  . GLU D 2 246 ? 226.741 230.386 282.309 1.00 50.74  ? 485 GLU E CB  1 
ATOM   7691 C CG  . GLU D 2 246 ? 226.244 230.624 280.900 1.00 55.27  ? 485 GLU E CG  1 
ATOM   7692 C CD  . GLU D 2 246 ? 225.065 231.569 280.857 1.00 60.75  ? 485 GLU E CD  1 
ATOM   7693 O OE1 . GLU D 2 246 ? 224.662 232.063 281.930 1.00 60.54  ? 485 GLU E OE1 1 
ATOM   7694 O OE2 . GLU D 2 246 ? 224.541 231.817 279.752 1.00 62.45  ? 485 GLU E OE2 1 
ATOM   7695 N N   . GLU D 2 247 ? 226.607 229.105 285.384 1.00 45.51  ? 486 GLU E N   1 
ATOM   7696 C CA  . GLU D 2 247 ? 227.307 228.660 286.579 1.00 44.10  ? 486 GLU E CA  1 
ATOM   7697 C C   . GLU D 2 247 ? 226.739 227.360 287.132 1.00 47.18  ? 486 GLU E C   1 
ATOM   7698 O O   . GLU D 2 247 ? 226.984 227.032 288.298 1.00 45.95  ? 486 GLU E O   1 
ATOM   7699 C CB  . GLU D 2 247 ? 227.262 229.748 287.652 1.00 47.32  ? 486 GLU E CB  1 
ATOM   7700 C CG  . GLU D 2 247 ? 228.582 230.454 287.876 1.00 51.16  ? 486 GLU E CG  1 
ATOM   7701 C CD  . GLU D 2 247 ? 228.581 231.287 289.140 1.00 59.22  ? 486 GLU E CD  1 
ATOM   7702 O OE1 . GLU D 2 247 ? 227.904 230.889 290.111 1.00 57.28  ? 486 GLU E OE1 1 
ATOM   7703 O OE2 . GLU D 2 247 ? 229.254 232.337 289.163 1.00 62.79  ? 486 GLU E OE2 1 
ATOM   7704 N N   . GLY D 2 248 ? 225.987 226.620 286.326 1.00 47.86  ? 487 GLY E N   1 
ATOM   7705 C CA  . GLY D 2 248 ? 225.343 225.409 286.779 1.00 47.26  ? 487 GLY E CA  1 
ATOM   7706 C C   . GLY D 2 248 ? 224.028 225.688 287.478 1.00 42.73  ? 487 GLY E C   1 
ATOM   7707 O O   . GLY D 2 248 ? 223.659 226.826 287.767 1.00 48.70  ? 487 GLY E O   1 
ATOM   7708 N N   . LEU D 2 249 ? 223.302 224.610 287.751 1.00 34.77  ? 488 LEU E N   1 
ATOM   7709 C CA  . LEU D 2 249 ? 222.030 224.666 288.459 1.00 33.86  ? 488 LEU E CA  1 
ATOM   7710 C C   . LEU D 2 249 ? 222.185 223.904 289.766 1.00 37.84  ? 488 LEU E C   1 
ATOM   7711 O O   . LEU D 2 249 ? 222.542 222.721 289.758 1.00 36.90  ? 488 LEU E O   1 
ATOM   7712 C CB  . LEU D 2 249 ? 220.909 224.078 287.601 1.00 36.88  ? 488 LEU E CB  1 
ATOM   7713 C CG  . LEU D 2 249 ? 219.501 224.003 288.183 1.00 34.35  ? 488 LEU E CG  1 
ATOM   7714 C CD1 . LEU D 2 249 ? 218.482 224.421 287.146 1.00 34.01  ? 488 LEU E CD1 1 
ATOM   7715 C CD2 . LEU D 2 249 ? 219.223 222.593 288.652 1.00 41.69  ? 488 LEU E CD2 1 
ATOM   7716 N N   . THR D 2 250 ? 221.923 224.575 290.883 1.00 37.59  ? 489 THR E N   1 
ATOM   7717 C CA  . THR D 2 250 ? 222.153 224.011 292.205 1.00 40.27  ? 489 THR E CA  1 
ATOM   7718 C C   . THR D 2 250 ? 220.836 223.863 292.950 1.00 38.81  ? 489 THR E C   1 
ATOM   7719 O O   . THR D 2 250 ? 220.051 224.814 293.026 1.00 37.93  ? 489 THR E O   1 
ATOM   7720 C CB  . THR D 2 250 ? 223.115 224.879 293.020 1.00 37.62  ? 489 THR E CB  1 
ATOM   7721 O OG1 . THR D 2 250 ? 224.252 225.216 292.218 1.00 43.10  ? 489 THR E OG1 1 
ATOM   7722 C CG2 . THR D 2 250 ? 223.584 224.129 294.252 1.00 31.23  ? 489 THR E CG2 1 
ATOM   7723 N N   . LEU D 2 251 ? 220.603 222.667 293.491 1.00 45.57  ? 490 LEU E N   1 
ATOM   7724 C CA  . LEU D 2 251 ? 219.496 222.390 294.405 1.00 47.48  ? 490 LEU E CA  1 
ATOM   7725 C C   . LEU D 2 251 ? 218.149 222.765 293.786 1.00 49.48  ? 490 LEU E C   1 
ATOM   7726 O O   . LEU D 2 251 ? 217.419 223.627 294.281 1.00 57.29  ? 490 LEU E O   1 
ATOM   7727 C CB  . LEU D 2 251 ? 219.708 223.106 295.743 1.00 48.62  ? 490 LEU E CB  1 
ATOM   7728 C CG  . LEU D 2 251 ? 220.344 222.295 296.874 1.00 45.09  ? 490 LEU E CG  1 
ATOM   7729 C CD1 . LEU D 2 251 ? 219.445 221.147 297.293 1.00 39.73  ? 490 LEU E CD1 1 
ATOM   7730 C CD2 . LEU D 2 251 ? 221.715 221.785 296.468 1.00 48.70  ? 490 LEU E CD2 1 
ATOM   7731 N N   . HIS D 2 252 ? 217.830 222.099 292.683 1.00 55.65  ? 491 HIS E N   1 
ATOM   7732 C CA  . HIS D 2 252 ? 216.521 222.262 292.070 1.00 56.13  ? 491 HIS E CA  1 
ATOM   7733 C C   . HIS D 2 252 ? 215.447 221.637 292.949 1.00 57.54  ? 491 HIS E C   1 
ATOM   7734 O O   . HIS D 2 252 ? 215.629 220.550 293.503 1.00 60.46  ? 491 HIS E O   1 
ATOM   7735 C CB  . HIS D 2 252 ? 216.499 221.618 290.687 1.00 60.56  ? 491 HIS E CB  1 
ATOM   7736 C CG  . HIS D 2 252 ? 215.383 222.097 289.814 1.00 57.58  ? 491 HIS E CG  1 
ATOM   7737 N ND1 . HIS D 2 252 ? 214.506 223.085 290.202 1.00 61.01  ? 491 HIS E ND1 1 
ATOM   7738 C CD2 . HIS D 2 252 ? 214.992 221.712 288.577 1.00 56.32  ? 491 HIS E CD2 1 
ATOM   7739 C CE1 . HIS D 2 252 ? 213.628 223.295 289.238 1.00 62.00  ? 491 HIS E CE1 1 
ATOM   7740 N NE2 . HIS D 2 252 ? 213.901 222.473 288.241 1.00 57.82  ? 491 HIS E NE2 1 
ATOM   7741 N N   . ARG D 2 253 ? 214.319 222.329 293.074 1.00 63.63  ? 492 ARG E N   1 
ATOM   7742 C CA  . ARG D 2 253 ? 213.176 221.821 293.815 1.00 66.18  ? 492 ARG E CA  1 
ATOM   7743 C C   . ARG D 2 253 ? 211.897 222.237 293.106 1.00 68.66  ? 492 ARG E C   1 
ATOM   7744 O O   . ARG D 2 253 ? 211.768 223.373 292.645 1.00 72.90  ? 492 ARG E O   1 
ATOM   7745 C CB  . ARG D 2 253 ? 213.160 222.331 295.261 1.00 69.35  ? 492 ARG E CB  1 
ATOM   7746 C CG  . ARG D 2 253 ? 214.299 221.815 296.118 1.00 69.28  ? 492 ARG E CG  1 
ATOM   7747 C CD  . ARG D 2 253 ? 214.127 220.343 296.429 1.00 70.13  ? 492 ARG E CD  1 
ATOM   7748 N NE  . ARG D 2 253 ? 214.993 219.920 297.521 1.00 72.81  ? 492 ARG E NE  1 
ATOM   7749 C CZ  . ARG D 2 253 ? 216.252 219.536 297.369 1.00 74.24  ? 492 ARG E CZ  1 
ATOM   7750 N NH1 . ARG D 2 253 ? 216.821 219.495 296.176 1.00 74.37  ? 492 ARG E NH1 1 
ATOM   7751 N NH2 . ARG D 2 253 ? 216.956 219.180 298.439 1.00 73.88  ? 492 ARG E NH2 1 
ATOM   7752 N N   . VAL D 2 254 ? 210.953 221.307 293.026 1.00 56.47  ? 493 VAL E N   1 
ATOM   7753 C CA  . VAL D 2 254 ? 209.661 221.586 292.413 1.00 58.57  ? 493 VAL E CA  1 
ATOM   7754 C C   . VAL D 2 254 ? 208.540 221.071 293.305 1.00 66.99  ? 493 VAL E C   1 
ATOM   7755 O O   . VAL D 2 254 ? 208.776 220.671 294.445 1.00 70.50  ? 493 VAL E O   1 
ATOM   7756 C CB  . VAL D 2 254 ? 209.560 220.974 291.007 1.00 59.74  ? 493 VAL E CB  1 
ATOM   7757 C CG1 . VAL D 2 254 ? 210.475 221.707 290.040 1.00 61.42  ? 493 VAL E CG1 1 
ATOM   7758 C CG2 . VAL D 2 254 ? 209.899 219.493 291.050 1.00 66.28  ? 493 VAL E CG2 1 
HETATM 7759 O O1  . EIP E 3 .   ? 219.574 229.395 279.022 1.00 64.33  ? 501 EIP D O1  1 
HETATM 7760 O O2  . EIP E 3 .   ? 219.521 228.783 276.633 1.00 68.88  ? 501 EIP D O2  1 
HETATM 7761 O O3  . EIP E 3 .   ? 217.629 229.996 277.633 1.00 62.74  ? 501 EIP D O3  1 
HETATM 7762 P P4  . EIP E 3 .   ? 218.692 228.955 277.880 1.00 71.86  ? 501 EIP D P4  1 
HETATM 7763 O O5  . EIP E 3 .   ? 217.949 227.534 278.243 1.00 59.05  ? 501 EIP D O5  1 
HETATM 7764 O O6  . EIP E 3 .   ? 219.901 226.126 277.300 1.00 54.16  ? 501 EIP D O6  1 
HETATM 7765 O O7  . EIP E 3 .   ? 219.010 225.556 279.508 1.00 69.33  ? 501 EIP D O7  1 
HETATM 7766 P P8  . EIP E 3 .   ? 218.645 226.047 278.130 1.00 69.60  ? 501 EIP D P8  1 
HETATM 7767 O O9  . EIP E 3 .   ? 217.559 225.012 277.449 1.00 66.12  ? 501 EIP D O9  1 
HETATM 7768 C C10 . EIP E 3 .   ? 216.281 224.930 278.014 1.00 62.01  ? 501 EIP D C10 1 
HETATM 7769 C C11 . EIP E 3 .   ? 215.311 224.365 276.978 1.00 59.41  ? 501 EIP D C11 1 
HETATM 7770 C C12 . EIP E 3 .   ? 213.848 224.650 277.309 1.00 61.85  ? 501 EIP D C12 1 
HETATM 7771 C C13 . EIP E 3 .   ? 213.107 224.988 276.019 1.00 65.86  ? 501 EIP D C13 1 
HETATM 7772 C C14 . EIP E 3 .   ? 213.223 223.408 277.932 1.00 61.14  ? 501 EIP D C14 1 
HETATM 7773 O O15 . EIP E 3 .   ? 213.208 223.892 275.154 1.00 64.93  ? 501 EIP D O15 1 
# 
