data_8Z9V
# 
_entry.id   8Z9V 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8Z9V         pdb_00008z9v 10.2210/pdb8z9v/pdb 
WWPDB D_1300047252 ?            ?                   
EMDB  EMD-39869    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-04-30 ? 
2 'EM metadata'     1 0 2025-04-30 ? 
3 FSC               1 0 2025-04-30 ? 
4 'Half map'        1 0 2025-04-30 1 
5 'Half map'        1 0 2025-04-30 2 
6 Image             1 0 2025-04-30 ? 
7 'Primary map'     1 0 2025-04-30 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1 1 'Structure model' repository 'Initial release' ? ? 
2 2 'EM metadata'     repository 'Initial release' ? ? 
3 3 FSC               repository 'Initial release' ? ? 
4 4 'Half map'        repository 'Initial release' ? ? 
5 5 'Half map'        repository 'Initial release' ? ? 
6 6 Image             repository 'Initial release' ? ? 
7 7 'Primary map'     repository 'Initial release' ? ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8Z9V 
_pdbx_database_status.recvd_initial_deposition_date   2024-04-23 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Amyloid beta and TTR' 
_pdbx_database_related.db_id          EMD-39869 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 3 
_pdbx_contact_author.email              sbjang@pusan.ac.kr 
_pdbx_contact_author.name_first         'Se Bok' 
_pdbx_contact_author.name_last          Jang 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-2266-0937 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Lee, H.N.'   1 0000-0002-9713-5045 
'Han, C.W.'   2 0000-0001-5125-886X 
'Jang, S.B.'  3 0000-0002-2266-0937 
'Jeong, M.S.' 4 0000-0002-4187-0243 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'Amyloid beta and TTR' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Lee, H.N.'   1 0000-0002-9713-5045 
primary 'Han, C.W.'   2 0000-0001-5125-886X 
primary 'Jang, S.B.'  3 0000-0002-2266-0937 
primary 'Jeong, M.S.' 4 0000-0002-4187-0243 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer man 'Amyloid-beta protein 42' 3762.293  1 ? ? ? ? 
2 polymer man Transthyretin             13831.412 2 ? ? ? ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
1 Abeta42,Beta-APP42   
2 ATTR,Prealbumin,TBPA 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no DSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA DSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA e   ? 
2 'polypeptide(L)' no no 
;GPTGTGESKRPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWK
ALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE
;
;GPTGTGESKRPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWK
ALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE
;
b,A ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   ASP n 
1 2   SER n 
1 3   GLY n 
1 4   TYR n 
1 5   GLU n 
1 6   VAL n 
1 7   HIS n 
1 8   HIS n 
1 9   GLN n 
1 10  LYS n 
1 11  LEU n 
1 12  VAL n 
1 13  PHE n 
1 14  PHE n 
1 15  ALA n 
1 16  GLU n 
1 17  ASP n 
1 18  VAL n 
1 19  GLY n 
1 20  SER n 
1 21  ASN n 
1 22  LYS n 
1 23  GLY n 
1 24  ALA n 
1 25  ILE n 
1 26  ILE n 
1 27  GLY n 
1 28  LEU n 
1 29  MET n 
1 30  VAL n 
1 31  GLY n 
1 32  GLY n 
1 33  VAL n 
1 34  VAL n 
1 35  ILE n 
1 36  ALA n 
2 1   GLY n 
2 2   PRO n 
2 3   THR n 
2 4   GLY n 
2 5   THR n 
2 6   GLY n 
2 7   GLU n 
2 8   SER n 
2 9   LYS n 
2 10  ARG n 
2 11  PRO n 
2 12  LEU n 
2 13  MET n 
2 14  VAL n 
2 15  LYS n 
2 16  VAL n 
2 17  LEU n 
2 18  ASP n 
2 19  ALA n 
2 20  VAL n 
2 21  ARG n 
2 22  GLY n 
2 23  SER n 
2 24  PRO n 
2 25  ALA n 
2 26  ILE n 
2 27  ASN n 
2 28  VAL n 
2 29  ALA n 
2 30  VAL n 
2 31  HIS n 
2 32  VAL n 
2 33  PHE n 
2 34  ARG n 
2 35  LYS n 
2 36  ALA n 
2 37  ALA n 
2 38  ASP n 
2 39  ASP n 
2 40  THR n 
2 41  TRP n 
2 42  GLU n 
2 43  PRO n 
2 44  PHE n 
2 45  ALA n 
2 46  SER n 
2 47  GLY n 
2 48  LYS n 
2 49  THR n 
2 50  SER n 
2 51  GLU n 
2 52  SER n 
2 53  GLY n 
2 54  GLU n 
2 55  LEU n 
2 56  HIS n 
2 57  GLY n 
2 58  LEU n 
2 59  THR n 
2 60  THR n 
2 61  GLU n 
2 62  GLU n 
2 63  GLU n 
2 64  PHE n 
2 65  VAL n 
2 66  GLU n 
2 67  GLY n 
2 68  ILE n 
2 69  TYR n 
2 70  LYS n 
2 71  VAL n 
2 72  GLU n 
2 73  ILE n 
2 74  ASP n 
2 75  THR n 
2 76  LYS n 
2 77  SER n 
2 78  TYR n 
2 79  TRP n 
2 80  LYS n 
2 81  ALA n 
2 82  LEU n 
2 83  GLY n 
2 84  ILE n 
2 85  SER n 
2 86  PRO n 
2 87  PHE n 
2 88  HIS n 
2 89  GLU n 
2 90  HIS n 
2 91  ALA n 
2 92  GLU n 
2 93  VAL n 
2 94  VAL n 
2 95  PHE n 
2 96  THR n 
2 97  ALA n 
2 98  ASN n 
2 99  ASP n 
2 100 SER n 
2 101 GLY n 
2 102 PRO n 
2 103 ARG n 
2 104 ARG n 
2 105 TYR n 
2 106 THR n 
2 107 ILE n 
2 108 ALA n 
2 109 ALA n 
2 110 LEU n 
2 111 LEU n 
2 112 SER n 
2 113 PRO n 
2 114 TYR n 
2 115 SER n 
2 116 TYR n 
2 117 SER n 
2 118 THR n 
2 119 THR n 
2 120 ALA n 
2 121 VAL n 
2 122 VAL n 
2 123 THR n 
2 124 ASN n 
2 125 PRO n 
2 126 LYS n 
2 127 GLU n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 36  human ? 'APP, A4, AD1' ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 'Escherichia coli' 
562 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 127 human ? 'TTR, PALB'    ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 'Escherichia coli' 
562 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   ASP 1   7   7   ASP ASP e . n 
A 1 2   SER 2   8   8   SER SER e . n 
A 1 3   GLY 3   9   9   GLY GLY e . n 
A 1 4   TYR 4   10  10  TYR TYR e . n 
A 1 5   GLU 5   11  11  GLU GLU e . n 
A 1 6   VAL 6   12  12  VAL VAL e . n 
A 1 7   HIS 7   13  13  HIS HIS e . n 
A 1 8   HIS 8   14  14  HIS HIS e . n 
A 1 9   GLN 9   15  15  GLN GLN e . n 
A 1 10  LYS 10  16  16  LYS LYS e . n 
A 1 11  LEU 11  17  17  LEU LEU e . n 
A 1 12  VAL 12  18  18  VAL VAL e . n 
A 1 13  PHE 13  19  19  PHE PHE e . n 
A 1 14  PHE 14  20  20  PHE PHE e . n 
A 1 15  ALA 15  21  21  ALA ALA e . n 
A 1 16  GLU 16  22  22  GLU GLU e . n 
A 1 17  ASP 17  23  23  ASP ASP e . n 
A 1 18  VAL 18  24  24  VAL VAL e . n 
A 1 19  GLY 19  25  25  GLY GLY e . n 
A 1 20  SER 20  26  26  SER SER e . n 
A 1 21  ASN 21  27  27  ASN ASN e . n 
A 1 22  LYS 22  28  28  LYS LYS e . n 
A 1 23  GLY 23  29  29  GLY GLY e . n 
A 1 24  ALA 24  30  30  ALA ALA e . n 
A 1 25  ILE 25  31  31  ILE ILE e . n 
A 1 26  ILE 26  32  32  ILE ILE e . n 
A 1 27  GLY 27  33  33  GLY GLY e . n 
A 1 28  LEU 28  34  34  LEU LEU e . n 
A 1 29  MET 29  35  35  MET MET e . n 
A 1 30  VAL 30  36  36  VAL VAL e . n 
A 1 31  GLY 31  37  37  GLY GLY e . n 
A 1 32  GLY 32  38  38  GLY GLY e . n 
A 1 33  VAL 33  39  39  VAL VAL e . n 
A 1 34  VAL 34  40  40  VAL VAL e . n 
A 1 35  ILE 35  41  41  ILE ILE e . n 
A 1 36  ALA 36  42  42  ALA ALA e . n 
B 2 1   GLY 1   1   1   GLY GLY b . n 
B 2 2   PRO 2   2   2   PRO PRO b . n 
B 2 3   THR 3   3   3   THR THR b . n 
B 2 4   GLY 4   4   4   GLY GLY b . n 
B 2 5   THR 5   5   5   THR THR b . n 
B 2 6   GLY 6   6   6   GLY GLY b . n 
B 2 7   GLU 7   7   7   GLU GLU b . n 
B 2 8   SER 8   8   8   SER SER b . n 
B 2 9   LYS 9   9   9   LYS LYS b . n 
B 2 10  ARG 10  10  10  ARG ARG b . n 
B 2 11  PRO 11  11  11  PRO PRO b . n 
B 2 12  LEU 12  12  12  LEU LEU b . n 
B 2 13  MET 13  13  13  MET MET b . n 
B 2 14  VAL 14  14  14  VAL VAL b . n 
B 2 15  LYS 15  15  15  LYS LYS b . n 
B 2 16  VAL 16  16  16  VAL VAL b . n 
B 2 17  LEU 17  17  17  LEU LEU b . n 
B 2 18  ASP 18  18  18  ASP ASP b . n 
B 2 19  ALA 19  19  19  ALA ALA b . n 
B 2 20  VAL 20  20  20  VAL VAL b . n 
B 2 21  ARG 21  21  21  ARG ARG b . n 
B 2 22  GLY 22  22  22  GLY GLY b . n 
B 2 23  SER 23  23  23  SER SER b . n 
B 2 24  PRO 24  24  24  PRO PRO b . n 
B 2 25  ALA 25  25  25  ALA ALA b . n 
B 2 26  ILE 26  26  26  ILE ILE b . n 
B 2 27  ASN 27  27  27  ASN ASN b . n 
B 2 28  VAL 28  28  28  VAL VAL b . n 
B 2 29  ALA 29  29  29  ALA ALA b . n 
B 2 30  VAL 30  30  30  VAL VAL b . n 
B 2 31  HIS 31  31  31  HIS HIS b . n 
B 2 32  VAL 32  32  32  VAL VAL b . n 
B 2 33  PHE 33  33  33  PHE PHE b . n 
B 2 34  ARG 34  34  34  ARG ARG b . n 
B 2 35  LYS 35  35  35  LYS LYS b . n 
B 2 36  ALA 36  36  36  ALA ALA b . n 
B 2 37  ALA 37  37  37  ALA ALA b . n 
B 2 38  ASP 38  38  38  ASP ASP b . n 
B 2 39  ASP 39  39  39  ASP ASP b . n 
B 2 40  THR 40  40  40  THR THR b . n 
B 2 41  TRP 41  41  41  TRP TRP b . n 
B 2 42  GLU 42  42  42  GLU GLU b . n 
B 2 43  PRO 43  43  43  PRO PRO b . n 
B 2 44  PHE 44  44  44  PHE PHE b . n 
B 2 45  ALA 45  45  45  ALA ALA b . n 
B 2 46  SER 46  46  46  SER SER b . n 
B 2 47  GLY 47  47  47  GLY GLY b . n 
B 2 48  LYS 48  48  48  LYS LYS b . n 
B 2 49  THR 49  49  49  THR THR b . n 
B 2 50  SER 50  50  50  SER SER b . n 
B 2 51  GLU 51  51  51  GLU GLU b . n 
B 2 52  SER 52  52  52  SER SER b . n 
B 2 53  GLY 53  53  53  GLY GLY b . n 
B 2 54  GLU 54  54  54  GLU GLU b . n 
B 2 55  LEU 55  55  55  LEU LEU b . n 
B 2 56  HIS 56  56  56  HIS HIS b . n 
B 2 57  GLY 57  57  57  GLY GLY b . n 
B 2 58  LEU 58  58  58  LEU LEU b . n 
B 2 59  THR 59  59  59  THR THR b . n 
B 2 60  THR 60  60  60  THR THR b . n 
B 2 61  GLU 61  61  61  GLU GLU b . n 
B 2 62  GLU 62  62  62  GLU GLU b . n 
B 2 63  GLU 63  63  63  GLU GLU b . n 
B 2 64  PHE 64  64  64  PHE PHE b . n 
B 2 65  VAL 65  65  65  VAL VAL b . n 
B 2 66  GLU 66  66  66  GLU GLU b . n 
B 2 67  GLY 67  67  67  GLY GLY b . n 
B 2 68  ILE 68  68  68  ILE ILE b . n 
B 2 69  TYR 69  69  69  TYR TYR b . n 
B 2 70  LYS 70  70  70  LYS LYS b . n 
B 2 71  VAL 71  71  71  VAL VAL b . n 
B 2 72  GLU 72  72  72  GLU GLU b . n 
B 2 73  ILE 73  73  73  ILE ILE b . n 
B 2 74  ASP 74  74  74  ASP ASP b . n 
B 2 75  THR 75  75  75  THR THR b . n 
B 2 76  LYS 76  76  76  LYS LYS b . n 
B 2 77  SER 77  77  77  SER SER b . n 
B 2 78  TYR 78  78  78  TYR TYR b . n 
B 2 79  TRP 79  79  79  TRP TRP b . n 
B 2 80  LYS 80  80  80  LYS LYS b . n 
B 2 81  ALA 81  81  81  ALA ALA b . n 
B 2 82  LEU 82  82  82  LEU LEU b . n 
B 2 83  GLY 83  83  83  GLY GLY b . n 
B 2 84  ILE 84  84  84  ILE ILE b . n 
B 2 85  SER 85  85  85  SER SER b . n 
B 2 86  PRO 86  86  86  PRO PRO b . n 
B 2 87  PHE 87  87  87  PHE PHE b . n 
B 2 88  HIS 88  88  88  HIS HIS b . n 
B 2 89  GLU 89  89  89  GLU GLU b . n 
B 2 90  HIS 90  90  90  HIS HIS b . n 
B 2 91  ALA 91  91  91  ALA ALA b . n 
B 2 92  GLU 92  92  92  GLU GLU b . n 
B 2 93  VAL 93  93  93  VAL VAL b . n 
B 2 94  VAL 94  94  94  VAL VAL b . n 
B 2 95  PHE 95  95  95  PHE PHE b . n 
B 2 96  THR 96  96  96  THR THR b . n 
B 2 97  ALA 97  97  97  ALA ALA b . n 
B 2 98  ASN 98  98  98  ASN ASN b . n 
B 2 99  ASP 99  99  99  ASP ASP b . n 
B 2 100 SER 100 100 100 SER SER b . n 
B 2 101 GLY 101 101 101 GLY GLY b . n 
B 2 102 PRO 102 102 102 PRO PRO b . n 
B 2 103 ARG 103 103 103 ARG ARG b . n 
B 2 104 ARG 104 104 104 ARG ARG b . n 
B 2 105 TYR 105 105 105 TYR TYR b . n 
B 2 106 THR 106 106 106 THR THR b . n 
B 2 107 ILE 107 107 107 ILE ILE b . n 
B 2 108 ALA 108 108 108 ALA ALA b . n 
B 2 109 ALA 109 109 109 ALA ALA b . n 
B 2 110 LEU 110 110 110 LEU LEU b . n 
B 2 111 LEU 111 111 111 LEU LEU b . n 
B 2 112 SER 112 112 112 SER SER b . n 
B 2 113 PRO 113 113 113 PRO PRO b . n 
B 2 114 TYR 114 114 114 TYR TYR b . n 
B 2 115 SER 115 115 115 SER SER b . n 
B 2 116 TYR 116 116 116 TYR TYR b . n 
B 2 117 SER 117 117 117 SER SER b . n 
B 2 118 THR 118 118 118 THR THR b . n 
B 2 119 THR 119 119 119 THR THR b . n 
B 2 120 ALA 120 120 120 ALA ALA b . n 
B 2 121 VAL 121 121 121 VAL VAL b . n 
B 2 122 VAL 122 122 122 VAL VAL b . n 
B 2 123 THR 123 123 123 THR THR b . n 
B 2 124 ASN 124 124 124 ASN ASN b . n 
B 2 125 PRO 125 125 125 PRO PRO b . n 
B 2 126 LYS 126 126 126 LYS LYS b . n 
B 2 127 GLU 127 127 127 GLU GLU b . n 
C 2 1   GLY 1   1   1   GLY GLY A . n 
C 2 2   PRO 2   2   2   PRO PRO A . n 
C 2 3   THR 3   3   3   THR THR A . n 
C 2 4   GLY 4   4   4   GLY GLY A . n 
C 2 5   THR 5   5   5   THR THR A . n 
C 2 6   GLY 6   6   6   GLY GLY A . n 
C 2 7   GLU 7   7   7   GLU GLU A . n 
C 2 8   SER 8   8   8   SER SER A . n 
C 2 9   LYS 9   9   9   LYS LYS A . n 
C 2 10  ARG 10  10  10  ARG ARG A . n 
C 2 11  PRO 11  11  11  PRO PRO A . n 
C 2 12  LEU 12  12  12  LEU LEU A . n 
C 2 13  MET 13  13  13  MET MET A . n 
C 2 14  VAL 14  14  14  VAL VAL A . n 
C 2 15  LYS 15  15  15  LYS LYS A . n 
C 2 16  VAL 16  16  16  VAL VAL A . n 
C 2 17  LEU 17  17  17  LEU LEU A . n 
C 2 18  ASP 18  18  18  ASP ASP A . n 
C 2 19  ALA 19  19  19  ALA ALA A . n 
C 2 20  VAL 20  20  20  VAL VAL A . n 
C 2 21  ARG 21  21  21  ARG ARG A . n 
C 2 22  GLY 22  22  22  GLY GLY A . n 
C 2 23  SER 23  23  23  SER SER A . n 
C 2 24  PRO 24  24  24  PRO PRO A . n 
C 2 25  ALA 25  25  25  ALA ALA A . n 
C 2 26  ILE 26  26  26  ILE ILE A . n 
C 2 27  ASN 27  27  27  ASN ASN A . n 
C 2 28  VAL 28  28  28  VAL VAL A . n 
C 2 29  ALA 29  29  29  ALA ALA A . n 
C 2 30  VAL 30  30  30  VAL VAL A . n 
C 2 31  HIS 31  31  31  HIS HIS A . n 
C 2 32  VAL 32  32  32  VAL VAL A . n 
C 2 33  PHE 33  33  33  PHE PHE A . n 
C 2 34  ARG 34  34  34  ARG ARG A . n 
C 2 35  LYS 35  35  35  LYS LYS A . n 
C 2 36  ALA 36  36  36  ALA ALA A . n 
C 2 37  ALA 37  37  37  ALA ALA A . n 
C 2 38  ASP 38  38  38  ASP ASP A . n 
C 2 39  ASP 39  39  39  ASP ASP A . n 
C 2 40  THR 40  40  40  THR THR A . n 
C 2 41  TRP 41  41  41  TRP TRP A . n 
C 2 42  GLU 42  42  42  GLU GLU A . n 
C 2 43  PRO 43  43  43  PRO PRO A . n 
C 2 44  PHE 44  44  44  PHE PHE A . n 
C 2 45  ALA 45  45  45  ALA ALA A . n 
C 2 46  SER 46  46  46  SER SER A . n 
C 2 47  GLY 47  47  47  GLY GLY A . n 
C 2 48  LYS 48  48  48  LYS LYS A . n 
C 2 49  THR 49  49  49  THR THR A . n 
C 2 50  SER 50  50  50  SER SER A . n 
C 2 51  GLU 51  51  51  GLU GLU A . n 
C 2 52  SER 52  52  52  SER SER A . n 
C 2 53  GLY 53  53  53  GLY GLY A . n 
C 2 54  GLU 54  54  54  GLU GLU A . n 
C 2 55  LEU 55  55  55  LEU LEU A . n 
C 2 56  HIS 56  56  56  HIS HIS A . n 
C 2 57  GLY 57  57  57  GLY GLY A . n 
C 2 58  LEU 58  58  58  LEU LEU A . n 
C 2 59  THR 59  59  59  THR THR A . n 
C 2 60  THR 60  60  60  THR THR A . n 
C 2 61  GLU 61  61  61  GLU GLU A . n 
C 2 62  GLU 62  62  62  GLU GLU A . n 
C 2 63  GLU 63  63  63  GLU GLU A . n 
C 2 64  PHE 64  64  64  PHE PHE A . n 
C 2 65  VAL 65  65  65  VAL VAL A . n 
C 2 66  GLU 66  66  66  GLU GLU A . n 
C 2 67  GLY 67  67  67  GLY GLY A . n 
C 2 68  ILE 68  68  68  ILE ILE A . n 
C 2 69  TYR 69  69  69  TYR TYR A . n 
C 2 70  LYS 70  70  70  LYS LYS A . n 
C 2 71  VAL 71  71  71  VAL VAL A . n 
C 2 72  GLU 72  72  72  GLU GLU A . n 
C 2 73  ILE 73  73  73  ILE ILE A . n 
C 2 74  ASP 74  74  74  ASP ASP A . n 
C 2 75  THR 75  75  75  THR THR A . n 
C 2 76  LYS 76  76  76  LYS LYS A . n 
C 2 77  SER 77  77  77  SER SER A . n 
C 2 78  TYR 78  78  78  TYR TYR A . n 
C 2 79  TRP 79  79  79  TRP TRP A . n 
C 2 80  LYS 80  80  80  LYS LYS A . n 
C 2 81  ALA 81  81  81  ALA ALA A . n 
C 2 82  LEU 82  82  82  LEU LEU A . n 
C 2 83  GLY 83  83  83  GLY GLY A . n 
C 2 84  ILE 84  84  84  ILE ILE A . n 
C 2 85  SER 85  85  85  SER SER A . n 
C 2 86  PRO 86  86  86  PRO PRO A . n 
C 2 87  PHE 87  87  87  PHE PHE A . n 
C 2 88  HIS 88  88  88  HIS HIS A . n 
C 2 89  GLU 89  89  89  GLU GLU A . n 
C 2 90  HIS 90  90  90  HIS HIS A . n 
C 2 91  ALA 91  91  91  ALA ALA A . n 
C 2 92  GLU 92  92  92  GLU GLU A . n 
C 2 93  VAL 93  93  93  VAL VAL A . n 
C 2 94  VAL 94  94  94  VAL VAL A . n 
C 2 95  PHE 95  95  95  PHE PHE A . n 
C 2 96  THR 96  96  96  THR THR A . n 
C 2 97  ALA 97  97  97  ALA ALA A . n 
C 2 98  ASN 98  98  98  ASN ASN A . n 
C 2 99  ASP 99  99  99  ASP ASP A . n 
C 2 100 SER 100 100 100 SER SER A . n 
C 2 101 GLY 101 101 101 GLY GLY A . n 
C 2 102 PRO 102 102 102 PRO PRO A . n 
C 2 103 ARG 103 103 103 ARG ARG A . n 
C 2 104 ARG 104 104 104 ARG ARG A . n 
C 2 105 TYR 105 105 105 TYR TYR A . n 
C 2 106 THR 106 106 106 THR THR A . n 
C 2 107 ILE 107 107 107 ILE ILE A . n 
C 2 108 ALA 108 108 108 ALA ALA A . n 
C 2 109 ALA 109 109 109 ALA ALA A . n 
C 2 110 LEU 110 110 110 LEU LEU A . n 
C 2 111 LEU 111 111 111 LEU LEU A . n 
C 2 112 SER 112 112 112 SER SER A . n 
C 2 113 PRO 113 113 113 PRO PRO A . n 
C 2 114 TYR 114 114 114 TYR TYR A . n 
C 2 115 SER 115 115 115 SER SER A . n 
C 2 116 TYR 116 116 116 TYR TYR A . n 
C 2 117 SER 117 117 117 SER SER A . n 
C 2 118 THR 118 118 118 THR THR A . n 
C 2 119 THR 119 119 119 THR THR A . n 
C 2 120 ALA 120 120 120 ALA ALA A . n 
C 2 121 VAL 121 121 121 VAL VAL A . n 
C 2 122 VAL 122 122 122 VAL VAL A . n 
C 2 123 THR 123 123 123 THR THR A . n 
C 2 124 ASN 124 124 124 ASN ASN A . n 
C 2 125 PRO 125 125 125 PRO PRO A . n 
C 2 126 LYS 126 126 126 LYS LYS A . n 
C 2 127 GLU 127 127 127 GLU GLU A . n 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8Z9V 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8Z9V 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8Z9V 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               ? 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8Z9V 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            . 
_refine.ls_d_res_low                             ? 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.0066  ? 2273 ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 1.1636  ? 3092 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 0.0635  ? 347  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.0083  ? 399  ? f_plane_restr      ? ? 
'ELECTRON MICROSCOPY' ? 14.4299 ? 1337 ? f_dihedral_angle_d ? ? 
# 
_struct.entry_id                     8Z9V 
_struct.title                        'Amyloid beta and TTR' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8Z9V 
_struct_keywords.text            'Amyloid beta, TTR, STRUCTURAL PROTEIN' 
_struct_keywords.pdbx_keywords   'STRUCTURAL PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 2 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP A4_HUMAN   P05067 ? 1 DSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA 678 
2 UNP TTHY_HUMAN P02766 ? 2 
;GPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWK
ALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE
;
21  
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8Z9V e 1 ? 36  ? P05067 678 ? 713 ? 7 42  
2 2 8Z9V b 1 ? 127 ? P02766 21  ? 147 ? 1 127 
3 2 8Z9V A 1 ? 127 ? P02766 21  ? 147 ? 1 127 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
2 8Z9V ARG b 10 ? UNP P02766 CYS 30 variant 10 1 
3 8Z9V ARG A 10 ? UNP P02766 CYS 30 variant 10 2 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   trimeric 
_pdbx_struct_assembly.oligomeric_count     3 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0 
_pdbx_struct_oper_list.matrix[1][2]         0.0 
_pdbx_struct_oper_list.matrix[1][3]         0.0 
_pdbx_struct_oper_list.vector[1]            0.0 
_pdbx_struct_oper_list.matrix[2][1]         0.0 
_pdbx_struct_oper_list.matrix[2][2]         1.0 
_pdbx_struct_oper_list.matrix[2][3]         0.0 
_pdbx_struct_oper_list.vector[2]            0.0 
_pdbx_struct_oper_list.matrix[3][1]         0.0 
_pdbx_struct_oper_list.matrix[3][2]         0.0 
_pdbx_struct_oper_list.matrix[3][3]         1.0 
_pdbx_struct_oper_list.vector[3]            0.0 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1 AA1 SER A 2  ? GLN A 9  ? SER e 8  GLN e 15 5 ? 8 
HELX_P HELX_P2 AA2 GLY A 23 ? GLY A 31 ? GLY e 29 GLY e 37 1 ? 9 
HELX_P HELX_P3 AA3 ASP B 74 ? TRP B 79 ? ASP b 74 TRP b 79 1 ? 6 
HELX_P HELX_P4 AA4 ASP C 74 ? TRP C 79 ? ASP A 74 TRP A 79 1 ? 6 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 2 ? 
AA2 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA2 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 PHE B 33 ? LYS B 35 ? PHE b 33 LYS b 35 
AA1 2 TRP B 41 ? PRO B 43 ? TRP b 41 PRO b 43 
AA2 1 PHE C 33 ? LYS C 35 ? PHE A 33 LYS A 35 
AA2 2 TRP C 41 ? PRO C 43 ? TRP A 41 PRO A 43 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N ARG B 34 ? N ARG b 34 O GLU B 42 ? O GLU b 42 
AA2 1 2 N ARG C 34 ? N ARG A 34 O GLU C 42 ? O GLU A 42 
# 
_pdbx_entry_details.entry_id                   8Z9V 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_ligand_of_interest     ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1 1 CA b GLU 62  ? ? CB b GLU 62  ? ? CG  b GLU 62  ? ? 128.10 113.40 14.70 2.20 N 
2 1 CA b TYR 105 ? ? CB b TYR 105 ? ? CG  b TYR 105 ? ? 126.91 113.40 13.51 1.90 N 
3 1 CB b TYR 105 ? ? CG b TYR 105 ? ? CD1 b TYR 105 ? ? 125.04 121.00 4.04  0.60 N 
4 1 CA A GLU 62  ? ? CB A GLU 62  ? ? CG  A GLU 62  ? ? 128.19 113.40 14.79 2.20 N 
5 1 CA A TYR 105 ? ? CB A TYR 105 ? ? CG  A TYR 105 ? ? 126.93 113.40 13.53 1.90 N 
6 1 CB A TYR 105 ? ? CG A TYR 105 ? ? CD1 A TYR 105 ? ? 125.03 121.00 4.03  0.60 N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 LEU e 17  ? ? -77.43  -150.87 
2  1 VAL e 18  ? ? -25.42  -42.82  
3  1 ASN e 27  ? ? -150.40 -159.98 
4  1 LYS e 28  ? ? 74.35   33.07   
5  1 ARG b 10  ? ? 47.69   72.61   
6  1 ASP b 39  ? ? 73.78   -8.84   
7  1 SER b 100 ? ? -141.25 41.82   
8  1 ARG A 10  ? ? 47.70   72.62   
9  1 ASP A 39  ? ? 73.84   -8.86   
10 1 SER A 100 ? ? -141.18 41.80   
# 
_space_group_symop.id              1 
_space_group_symop.operation_xyz   x,y,z 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8Z9V 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    8Z9V 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  7.84 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               93330 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.82 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'The complex of Amyloid beta and TTR' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       '1, 2' 
# 
_em_imaging.entry_id                        8Z9V 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'TFS GLACIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            200 
_em_imaging.illumination_mode               'SPOT SCAN' 
_em_imaging.mode                            'DARK FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             1000 
_em_imaging.nominal_defocus_max             3000 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_sample_support.id               1 
_em_sample_support.film_material    ? 
_em_sample_support.method           ? 
_em_sample_support.grid_material    GOLD 
_em_sample_support.grid_mesh_size   200 
_em_sample_support.grid_type        'Quantifoil R2/2' 
_em_sample_support.details          ? 
_em_sample_support.specimen_id      1 
_em_sample_support.citation_id      ? 
# 
_em_vitrification.entry_id              8Z9V 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          NITROGEN 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                8Z9V 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
PHE N    N N N 247 
PHE CA   C N S 248 
PHE C    C N N 249 
PHE O    O N N 250 
PHE CB   C N N 251 
PHE CG   C Y N 252 
PHE CD1  C Y N 253 
PHE CD2  C Y N 254 
PHE CE1  C Y N 255 
PHE CE2  C Y N 256 
PHE CZ   C Y N 257 
PHE OXT  O N N 258 
PHE H    H N N 259 
PHE H2   H N N 260 
PHE HA   H N N 261 
PHE HB2  H N N 262 
PHE HB3  H N N 263 
PHE HD1  H N N 264 
PHE HD2  H N N 265 
PHE HE1  H N N 266 
PHE HE2  H N N 267 
PHE HZ   H N N 268 
PHE HXT  H N N 269 
PRO N    N N N 270 
PRO CA   C N S 271 
PRO C    C N N 272 
PRO O    O N N 273 
PRO CB   C N N 274 
PRO CG   C N N 275 
PRO CD   C N N 276 
PRO OXT  O N N 277 
PRO H    H N N 278 
PRO HA   H N N 279 
PRO HB2  H N N 280 
PRO HB3  H N N 281 
PRO HG2  H N N 282 
PRO HG3  H N N 283 
PRO HD2  H N N 284 
PRO HD3  H N N 285 
PRO HXT  H N N 286 
SER N    N N N 287 
SER CA   C N S 288 
SER C    C N N 289 
SER O    O N N 290 
SER CB   C N N 291 
SER OG   O N N 292 
SER OXT  O N N 293 
SER H    H N N 294 
SER H2   H N N 295 
SER HA   H N N 296 
SER HB2  H N N 297 
SER HB3  H N N 298 
SER HG   H N N 299 
SER HXT  H N N 300 
THR N    N N N 301 
THR CA   C N S 302 
THR C    C N N 303 
THR O    O N N 304 
THR CB   C N R 305 
THR OG1  O N N 306 
THR CG2  C N N 307 
THR OXT  O N N 308 
THR H    H N N 309 
THR H2   H N N 310 
THR HA   H N N 311 
THR HB   H N N 312 
THR HG1  H N N 313 
THR HG21 H N N 314 
THR HG22 H N N 315 
THR HG23 H N N 316 
THR HXT  H N N 317 
TRP N    N N N 318 
TRP CA   C N S 319 
TRP C    C N N 320 
TRP O    O N N 321 
TRP CB   C N N 322 
TRP CG   C Y N 323 
TRP CD1  C Y N 324 
TRP CD2  C Y N 325 
TRP NE1  N Y N 326 
TRP CE2  C Y N 327 
TRP CE3  C Y N 328 
TRP CZ2  C Y N 329 
TRP CZ3  C Y N 330 
TRP CH2  C Y N 331 
TRP OXT  O N N 332 
TRP H    H N N 333 
TRP H2   H N N 334 
TRP HA   H N N 335 
TRP HB2  H N N 336 
TRP HB3  H N N 337 
TRP HD1  H N N 338 
TRP HE1  H N N 339 
TRP HE3  H N N 340 
TRP HZ2  H N N 341 
TRP HZ3  H N N 342 
TRP HH2  H N N 343 
TRP HXT  H N N 344 
TYR N    N N N 345 
TYR CA   C N S 346 
TYR C    C N N 347 
TYR O    O N N 348 
TYR CB   C N N 349 
TYR CG   C Y N 350 
TYR CD1  C Y N 351 
TYR CD2  C Y N 352 
TYR CE1  C Y N 353 
TYR CE2  C Y N 354 
TYR CZ   C Y N 355 
TYR OH   O N N 356 
TYR OXT  O N N 357 
TYR H    H N N 358 
TYR H2   H N N 359 
TYR HA   H N N 360 
TYR HB2  H N N 361 
TYR HB3  H N N 362 
TYR HD1  H N N 363 
TYR HD2  H N N 364 
TYR HE1  H N N 365 
TYR HE2  H N N 366 
TYR HH   H N N 367 
TYR HXT  H N N 368 
VAL N    N N N 369 
VAL CA   C N S 370 
VAL C    C N N 371 
VAL O    O N N 372 
VAL CB   C N N 373 
VAL CG1  C N N 374 
VAL CG2  C N N 375 
VAL OXT  O N N 376 
VAL H    H N N 377 
VAL H2   H N N 378 
VAL HA   H N N 379 
VAL HB   H N N 380 
VAL HG11 H N N 381 
VAL HG12 H N N 382 
VAL HG13 H N N 383 
VAL HG21 H N N 384 
VAL HG22 H N N 385 
VAL HG23 H N N 386 
VAL HXT  H N N 387 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SER N   CA   sing N N 275 
SER N   H    sing N N 276 
SER N   H2   sing N N 277 
SER CA  C    sing N N 278 
SER CA  CB   sing N N 279 
SER CA  HA   sing N N 280 
SER C   O    doub N N 281 
SER C   OXT  sing N N 282 
SER CB  OG   sing N N 283 
SER CB  HB2  sing N N 284 
SER CB  HB3  sing N N 285 
SER OG  HG   sing N N 286 
SER OXT HXT  sing N N 287 
THR N   CA   sing N N 288 
THR N   H    sing N N 289 
THR N   H2   sing N N 290 
THR CA  C    sing N N 291 
THR CA  CB   sing N N 292 
THR CA  HA   sing N N 293 
THR C   O    doub N N 294 
THR C   OXT  sing N N 295 
THR CB  OG1  sing N N 296 
THR CB  CG2  sing N N 297 
THR CB  HB   sing N N 298 
THR OG1 HG1  sing N N 299 
THR CG2 HG21 sing N N 300 
THR CG2 HG22 sing N N 301 
THR CG2 HG23 sing N N 302 
THR OXT HXT  sing N N 303 
TRP N   CA   sing N N 304 
TRP N   H    sing N N 305 
TRP N   H2   sing N N 306 
TRP CA  C    sing N N 307 
TRP CA  CB   sing N N 308 
TRP CA  HA   sing N N 309 
TRP C   O    doub N N 310 
TRP C   OXT  sing N N 311 
TRP CB  CG   sing N N 312 
TRP CB  HB2  sing N N 313 
TRP CB  HB3  sing N N 314 
TRP CG  CD1  doub Y N 315 
TRP CG  CD2  sing Y N 316 
TRP CD1 NE1  sing Y N 317 
TRP CD1 HD1  sing N N 318 
TRP CD2 CE2  doub Y N 319 
TRP CD2 CE3  sing Y N 320 
TRP NE1 CE2  sing Y N 321 
TRP NE1 HE1  sing N N 322 
TRP CE2 CZ2  sing Y N 323 
TRP CE3 CZ3  doub Y N 324 
TRP CE3 HE3  sing N N 325 
TRP CZ2 CH2  doub Y N 326 
TRP CZ2 HZ2  sing N N 327 
TRP CZ3 CH2  sing Y N 328 
TRP CZ3 HZ3  sing N N 329 
TRP CH2 HH2  sing N N 330 
TRP OXT HXT  sing N N 331 
TYR N   CA   sing N N 332 
TYR N   H    sing N N 333 
TYR N   H2   sing N N 334 
TYR CA  C    sing N N 335 
TYR CA  CB   sing N N 336 
TYR CA  HA   sing N N 337 
TYR C   O    doub N N 338 
TYR C   OXT  sing N N 339 
TYR CB  CG   sing N N 340 
TYR CB  HB2  sing N N 341 
TYR CB  HB3  sing N N 342 
TYR CG  CD1  doub Y N 343 
TYR CG  CD2  sing Y N 344 
TYR CD1 CE1  sing Y N 345 
TYR CD1 HD1  sing N N 346 
TYR CD2 CE2  doub Y N 347 
TYR CD2 HD2  sing N N 348 
TYR CE1 CZ   doub Y N 349 
TYR CE1 HE1  sing N N 350 
TYR CE2 CZ   sing Y N 351 
TYR CE2 HE2  sing N N 352 
TYR CZ  OH   sing N N 353 
TYR OH  HH   sing N N 354 
TYR OXT HXT  sing N N 355 
VAL N   CA   sing N N 356 
VAL N   H    sing N N 357 
VAL N   H2   sing N N 358 
VAL CA  C    sing N N 359 
VAL CA  CB   sing N N 360 
VAL CA  HA   sing N N 361 
VAL C   O    doub N N 362 
VAL C   OXT  sing N N 363 
VAL CB  CG1  sing N N 364 
VAL CB  CG2  sing N N 365 
VAL CB  HB   sing N N 366 
VAL CG1 HG11 sing N N 367 
VAL CG1 HG12 sing N N 368 
VAL CG1 HG13 sing N N 369 
VAL CG2 HG21 sing N N 370 
VAL CG2 HG22 sing N N 371 
VAL CG2 HG23 sing N N 372 
VAL OXT HXT  sing N N 373 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-04-23 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           8Z9V 
_em_admin.last_update        2025-04-30 
_em_admin.map_release_date   2025-04-30 
_em_admin.title              'Amyloid beta and TTR' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          562 
_em_entity_assembly_recombinant.organism             'Escherichia coli' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         50.0 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'FEI FALCON III (4k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? ? ? 
'IMAGE ACQUISITION'        ? 2  ? ? 1 ? ? 
MASKING                    ? 3  ? ? ? ? ? 
'CTF CORRECTION'           ? 4  1 ? ? ? ? 
'LAYERLINE INDEXING'       ? 5  ? ? ? ? ? 
'DIFFRACTION INDEXING'     ? 6  ? ? ? ? ? 
'MODEL FITTING'            ? 7  ? ? ? ? ? 
'MODEL REFINEMENT'         ? 8  ? ? ? ? ? 
OTHER                      ? 9  ? ? ? ? ? 
'INITIAL EULER ASSIGNMENT' ? 10 1 ? ? ? ? 
'FINAL EULER ASSIGNMENT'   ? 11 1 ? ? ? ? 
CLASSIFICATION             ? 12 1 ? ? ? ? 
RECONSTRUCTION             ? 13 1 ? ? ? ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'Not funded' 
_pdbx_audit_support.country                ? 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_space_group.crystal_system   triclinic 
_space_group.name_H-M_alt     'P 1' 
_space_group.IT_number        1 
_space_group.name_Hall        'P 1' 
_space_group.id               1 
# 
_atom_sites.entry_id                    8Z9V 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM 1    N N   . ASP A 1 1   ? -23.39600 3.97664   16.14750  1.000 832.44009 ? 7   ASP e N   1 
ATOM 2    C CA  . ASP A 1 1   ? -22.64600 3.86064   14.90450  1.000 832.44009 ? 7   ASP e CA  1 
ATOM 3    C C   . ASP A 1 1   ? -21.19000 3.51864   15.17550  1.000 832.44009 ? 7   ASP e C   1 
ATOM 4    O O   . ASP A 1 1   ? -20.72500 3.59864   16.31050  1.000 832.44009 ? 7   ASP e O   1 
ATOM 5    C CB  . ASP A 1 1   ? -22.73800 5.15464   14.10050  1.000 832.44009 ? 7   ASP e CB  1 
ATOM 6    C CG  . ASP A 1 1   ? -24.16400 5.53464   13.77950  1.000 832.44009 ? 7   ASP e CG  1 
ATOM 7    O OD1 . ASP A 1 1   ? -24.92200 5.84664   14.72150  1.000 832.44009 ? 7   ASP e OD1 1 
ATOM 8    O OD2 . ASP A 1 1   ? -24.52800 5.52364   12.58550  1.000 832.44009 ? 7   ASP e OD2 1 
ATOM 9    N N   . SER A 1 2   ? -20.47300 3.14164   14.12150  1.000 793.50159 ? 8   SER e N   1 
ATOM 10   C CA  . SER A 1 2   ? -19.07200 2.77264   14.25150  1.000 793.50159 ? 8   SER e CA  1 
ATOM 11   C C   . SER A 1 2   ? -18.37000 3.04764   12.93250  1.000 793.50159 ? 8   SER e C   1 
ATOM 12   O O   . SER A 1 2   ? -18.98900 3.46464   11.95150  1.000 793.50159 ? 8   SER e O   1 
ATOM 13   C CB  . SER A 1 2   ? -18.90800 1.30164   14.64050  1.000 793.50159 ? 8   SER e CB  1 
ATOM 14   O OG  . SER A 1 2   ? -18.83800 0.48264   13.48550  1.000 793.50159 ? 8   SER e OG  1 
ATOM 15   N N   . GLY A 1 3   ? -17.06200 2.79164   12.92450  1.000 687.56772 ? 9   GLY e N   1 
ATOM 16   C CA  . GLY A 1 3   ? -16.25600 2.96964   11.73150  1.000 687.56772 ? 9   GLY e CA  1 
ATOM 17   C C   . GLY A 1 3   ? -16.45200 1.90664   10.67250  1.000 687.56772 ? 9   GLY e C   1 
ATOM 18   O O   . GLY A 1 3   ? -15.94200 2.06464   9.55950   1.000 687.56772 ? 9   GLY e O   1 
ATOM 19   N N   . TYR A 1 4   ? -17.16300 0.82964   10.99050  1.000 639.08990 ? 10  TYR e N   1 
ATOM 20   C CA  . TYR A 1 4   ? -17.36400 -0.25036  10.03850  1.000 639.08990 ? 10  TYR e CA  1 
ATOM 21   C C   . TYR A 1 4   ? -18.61800 -0.07536  9.19450   1.000 639.08990 ? 10  TYR e C   1 
ATOM 22   O O   . TYR A 1 4   ? -19.16600 -1.06736  8.70550   1.000 639.08990 ? 10  TYR e O   1 
ATOM 23   C CB  . TYR A 1 4   ? -17.34200 -1.57436  10.78850  1.000 639.08990 ? 10  TYR e CB  1 
ATOM 24   C CG  . TYR A 1 4   ? -16.03800 -1.71036  11.53750  1.000 639.08990 ? 10  TYR e CG  1 
ATOM 25   C CD1 . TYR A 1 4   ? -16.01100 -2.02136  12.88850  1.000 639.08990 ? 10  TYR e CD1 1 
ATOM 26   C CD2 . TYR A 1 4   ? -14.82600 -1.47936  10.89250  1.000 639.08990 ? 10  TYR e CD2 1 
ATOM 27   C CE1 . TYR A 1 4   ? -14.80900 -2.12436  13.57350  1.000 639.08990 ? 10  TYR e CE1 1 
ATOM 28   C CE2 . TYR A 1 4   ? -13.62400 -1.58236  11.56350  1.000 639.08990 ? 10  TYR e CE2 1 
ATOM 29   C CZ  . TYR A 1 4   ? -13.62000 -1.90436  12.90450  1.000 639.08990 ? 10  TYR e CZ  1 
ATOM 30   O OH  . TYR A 1 4   ? -12.42500 -2.00536  13.57850  1.000 639.08990 ? 10  TYR e OH  1 
ATOM 31   N N   . GLU A 1 5   ? -19.06800 1.16764   9.01350   1.000 641.80753 ? 11  GLU e N   1 
ATOM 32   C CA  . GLU A 1 5   ? -19.95700 1.57464   7.93250   1.000 641.80753 ? 11  GLU e CA  1 
ATOM 33   C C   . GLU A 1 5   ? -19.28500 1.46964   6.56550   1.000 641.80753 ? 11  GLU e C   1 
ATOM 34   O O   . GLU A 1 5   ? -19.96400 1.50064   5.53550   1.000 641.80753 ? 11  GLU e O   1 
ATOM 35   C CB  . GLU A 1 5   ? -20.42600 3.01864   8.18450   1.000 641.80753 ? 11  GLU e CB  1 
ATOM 36   C CG  . GLU A 1 5   ? -21.62200 3.51864   7.37250   1.000 641.80753 ? 11  GLU e CG  1 
ATOM 37   C CD  . GLU A 1 5   ? -22.92600 2.86564   7.77450   1.000 641.80753 ? 11  GLU e CD  1 
ATOM 38   O OE1 . GLU A 1 5   ? -23.02600 2.39264   8.92550   1.000 641.80753 ? 11  GLU e OE1 1 
ATOM 39   O OE2 . GLU A 1 5   ? -23.85500 2.83164   6.94150   1.000 641.80753 ? 11  GLU e OE2 1 
ATOM 40   N N   . VAL A 1 6   ? -17.95800 1.31964   6.53950   1.000 625.55405 ? 12  VAL e N   1 
ATOM 41   C CA  . VAL A 1 6   ? -17.23400 0.90764   5.34050   1.000 625.55405 ? 12  VAL e CA  1 
ATOM 42   C C   . VAL A 1 6   ? -17.67900 -0.48136  4.89450   1.000 625.55405 ? 12  VAL e C   1 
ATOM 43   O O   . VAL A 1 6   ? -17.63800 -0.81336  3.70450   1.000 625.55405 ? 12  VAL e O   1 
ATOM 44   C CB  . VAL A 1 6   ? -15.71100 0.98764   5.62150   1.000 625.55405 ? 12  VAL e CB  1 
ATOM 45   C CG1 . VAL A 1 6   ? -15.30900 0.11964   6.82250   1.000 625.55405 ? 12  VAL e CG1 1 
ATOM 46   C CG2 . VAL A 1 6   ? -14.87100 0.68164   4.38450   1.000 625.55405 ? 12  VAL e CG2 1 
ATOM 47   N N   . HIS A 1 7   ? -18.13900 -1.30136  5.82550   1.000 648.43708 ? 13  HIS e N   1 
ATOM 48   C CA  . HIS A 1 7   ? -18.71700 -2.58336  5.48550   1.000 648.43708 ? 13  HIS e CA  1 
ATOM 49   C C   . HIS A 1 7   ? -20.17700 -2.46436  5.08950   1.000 648.43708 ? 13  HIS e C   1 
ATOM 50   O O   . HIS A 1 7   ? -20.76900 -3.43636  4.61050   1.000 648.43708 ? 13  HIS e O   1 
ATOM 51   C CB  . HIS A 1 7   ? -18.54300 -3.54236  6.65850   1.000 648.43708 ? 13  HIS e CB  1 
ATOM 52   C CG  . HIS A 1 7   ? -17.14000 -3.59836  7.18250   1.000 648.43708 ? 13  HIS e CG  1 
ATOM 53   N ND1 . HIS A 1 7   ? -16.84800 -3.96236  8.47750   1.000 648.43708 ? 13  HIS e ND1 1 
ATOM 54   C CD2 . HIS A 1 7   ? -15.94900 -3.35736  6.58250   1.000 648.43708 ? 13  HIS e CD2 1 
ATOM 55   C CE1 . HIS A 1 7   ? -15.54000 -3.92836  8.65750   1.000 648.43708 ? 13  HIS e CE1 1 
ATOM 56   N NE2 . HIS A 1 7   ? -14.97200 -3.56036  7.52450   1.000 648.43708 ? 13  HIS e NE2 1 
ATOM 57   N N   . HIS A 1 8   ? -20.76800 -1.28036  5.25650   1.000 567.11040 ? 14  HIS e N   1 
ATOM 58   C CA  . HIS A 1 8   ? -22.07500 -1.02936  4.66350   1.000 567.11040 ? 14  HIS e CA  1 
ATOM 59   C C   . HIS A 1 8   ? -21.93000 -0.64436  3.19950   1.000 567.11040 ? 14  HIS e C   1 
ATOM 60   O O   . HIS A 1 8   ? -22.92800 -0.51136  2.48750   1.000 567.11040 ? 14  HIS e O   1 
ATOM 61   C CB  . HIS A 1 8   ? -22.81200 0.05864   5.44150   1.000 567.11040 ? 14  HIS e CB  1 
ATOM 62   C CG  . HIS A 1 8   ? -24.30000 -0.08936  5.44650   1.000 567.11040 ? 14  HIS e CG  1 
ATOM 63   N ND1 . HIS A 1 8   ? -24.94200 -1.16936  6.01150   1.000 567.11040 ? 14  HIS e ND1 1 
ATOM 64   C CD2 . HIS A 1 8   ? -25.27500 0.71364   4.95750   1.000 567.11040 ? 14  HIS e CD2 1 
ATOM 65   C CE1 . HIS A 1 8   ? -26.24800 -1.02236  5.87750   1.000 567.11040 ? 14  HIS e CE1 1 
ATOM 66   N NE2 . HIS A 1 8   ? -26.47600 0.10864   5.23550   1.000 567.11040 ? 14  HIS e NE2 1 
ATOM 67   N N   . GLN A 1 9   ? -20.69800 -0.40836  2.74550   1.000 577.03249 ? 15  GLN e N   1 
ATOM 68   C CA  . GLN A 1 9   ? -20.41900 -0.50736  1.32050   1.000 577.03249 ? 15  GLN e CA  1 
ATOM 69   C C   . GLN A 1 9   ? -20.40200 -1.96436  0.89350   1.000 577.03249 ? 15  GLN e C   1 
ATOM 70   O O   . GLN A 1 9   ? -20.86100 -2.30636  -0.20250  1.000 577.03249 ? 15  GLN e O   1 
ATOM 71   C CB  . GLN A 1 9   ? -19.08800 0.17664   0.99650   1.000 577.03249 ? 15  GLN e CB  1 
ATOM 72   C CG  . GLN A 1 9   ? -18.50900 -0.12836  -0.37650  1.000 577.03249 ? 15  GLN e CG  1 
ATOM 73   C CD  . GLN A 1 9   ? -17.41200 -1.17336  -0.32250  1.000 577.03249 ? 15  GLN e CD  1 
ATOM 74   O OE1 . GLN A 1 9   ? -16.78600 -1.37636  0.71650   1.000 577.03249 ? 15  GLN e OE1 1 
ATOM 75   N NE2 . GLN A 1 9   ? -17.18400 -1.85336  -1.44050  1.000 577.03249 ? 15  GLN e NE2 1 
ATOM 76   N N   . LYS A 1 10  ? -19.95900 -2.85036  1.78350   1.000 571.37019 ? 16  LYS e N   1 
ATOM 77   C CA  . LYS A 1 10  ? -19.84200 -4.27236  1.48550   1.000 571.37019 ? 16  LYS e CA  1 
ATOM 78   C C   . LYS A 1 10  ? -21.15600 -5.03236  1.60150   1.000 571.37019 ? 16  LYS e C   1 
ATOM 79   O O   . LYS A 1 10  ? -21.14300 -6.23736  1.86550   1.000 571.37019 ? 16  LYS e O   1 
ATOM 80   C CB  . LYS A 1 10  ? -18.78900 -4.90836  2.39050   1.000 571.37019 ? 16  LYS e CB  1 
ATOM 81   C CG  . LYS A 1 10  ? -17.47600 -4.17436  2.30050   1.000 571.37019 ? 16  LYS e CG  1 
ATOM 82   C CD  . LYS A 1 10  ? -16.43900 -4.72436  3.23250   1.000 571.37019 ? 16  LYS e CD  1 
ATOM 83   C CE  . LYS A 1 10  ? -15.21500 -3.84136  3.19250   1.000 571.37019 ? 16  LYS e CE  1 
ATOM 84   N NZ  . LYS A 1 10  ? -15.62600 -2.42436  3.31850   1.000 571.37019 ? 16  LYS e NZ  1 
ATOM 85   N N   . LEU A 1 11  ? -22.28000 -4.34836  1.39350   1.000 540.95348 ? 17  LEU e N   1 
ATOM 86   C CA  . LEU A 1 11  ? -23.57900 -4.92036  1.06150   1.000 540.95348 ? 17  LEU e CA  1 
ATOM 87   C C   . LEU A 1 11  ? -23.60100 -5.31536  -0.40950  1.000 540.95348 ? 17  LEU e C   1 
ATOM 88   O O   . LEU A 1 11  ? -22.58200 -5.76036  -0.95050  1.000 540.95348 ? 17  LEU e O   1 
ATOM 89   C CB  . LEU A 1 11  ? -24.71600 -3.94236  1.34950   1.000 540.95348 ? 17  LEU e CB  1 
ATOM 90   C CG  . LEU A 1 11  ? -24.73500 -3.20336  2.67750   1.000 540.95348 ? 17  LEU e CG  1 
ATOM 91   C CD1 . LEU A 1 11  ? -25.80500 -2.14336  2.59650   1.000 540.95348 ? 17  LEU e CD1 1 
ATOM 92   C CD2 . LEU A 1 11  ? -24.99800 -4.15236  3.82650   1.000 540.95348 ? 17  LEU e CD2 1 
ATOM 93   N N   . VAL A 1 12  ? -24.80300 -5.27336  -1.00550  1.000 495.49776 ? 18  VAL e N   1 
ATOM 94   C CA  . VAL A 1 12  ? -25.13700 -5.36736  -2.43550  1.000 495.49776 ? 18  VAL e CA  1 
ATOM 95   C C   . VAL A 1 12  ? -24.02000 -4.93236  -3.38250  1.000 495.49776 ? 18  VAL e C   1 
ATOM 96   O O   . VAL A 1 12  ? -23.74400 -5.59436  -4.39050  1.000 495.49776 ? 18  VAL e O   1 
ATOM 97   C CB  . VAL A 1 12  ? -26.40000 -4.51936  -2.70250  1.000 495.49776 ? 18  VAL e CB  1 
ATOM 98   C CG1 . VAL A 1 12  ? -26.78600 -4.51136  -4.17750  1.000 495.49776 ? 18  VAL e CG1 1 
ATOM 99   C CG2 . VAL A 1 12  ? -27.54900 -5.00936  -1.85550  1.000 495.49776 ? 18  VAL e CG2 1 
ATOM 100  N N   . PHE A 1 13  ? -23.35900 -3.83036  -3.04650  1.000 551.84683 ? 19  PHE e N   1 
ATOM 101  C CA  . PHE A 1 13  ? -22.19600 -3.35436  -3.77350  1.000 551.84683 ? 19  PHE e CA  1 
ATOM 102  C C   . PHE A 1 13  ? -20.92900 -4.08836  -3.32650  1.000 551.84683 ? 19  PHE e C   1 
ATOM 103  O O   . PHE A 1 13  ? -20.01400 -3.46236  -2.78150  1.000 551.84683 ? 19  PHE e O   1 
ATOM 104  C CB  . PHE A 1 13  ? -22.04200 -1.85236  -3.53050  1.000 551.84683 ? 19  PHE e CB  1 
ATOM 105  C CG  . PHE A 1 13  ? -23.33300 -1.08136  -3.65250  1.000 551.84683 ? 19  PHE e CG  1 
ATOM 106  C CD1 . PHE A 1 13  ? -23.81700 -0.71636  -4.89550  1.000 551.84683 ? 19  PHE e CD1 1 
ATOM 107  C CD2 . PHE A 1 13  ? -24.06300 -0.72736  -2.52050  1.000 551.84683 ? 19  PHE e CD2 1 
ATOM 108  C CE1 . PHE A 1 13  ? -24.99900 -0.01236  -5.01350  1.000 551.84683 ? 19  PHE e CE1 1 
ATOM 109  C CE2 . PHE A 1 13  ? -25.25000 -0.02736  -2.63350  1.000 551.84683 ? 19  PHE e CE2 1 
ATOM 110  C CZ  . PHE A 1 13  ? -25.71600 0.33164   -3.88150  1.000 551.84683 ? 19  PHE e CZ  1 
ATOM 111  N N   . PHE A 1 14  ? -20.88000 -5.41336  -3.55550  1.000 359.58829 ? 20  PHE e N   1 
ATOM 112  C CA  . PHE A 1 14  ? -19.67300 -6.23336  -3.39450  1.000 359.58829 ? 20  PHE e CA  1 
ATOM 113  C C   . PHE A 1 14  ? -19.82600 -7.60836  -4.04350  1.000 359.58829 ? 20  PHE e C   1 
ATOM 114  O O   . PHE A 1 14  ? -20.79200 -8.32036  -3.75350  1.000 359.58829 ? 20  PHE e O   1 
ATOM 115  C CB  . PHE A 1 14  ? -19.31700 -6.44236  -1.91650  1.000 359.58829 ? 20  PHE e CB  1 
ATOM 116  C CG  . PHE A 1 14  ? -18.03800 -7.20336  -1.70950  1.000 359.58829 ? 20  PHE e CG  1 
ATOM 117  C CD1 . PHE A 1 14  ? -16.81700 -6.59536  -1.95050  1.000 359.58829 ? 20  PHE e CD1 1 
ATOM 118  C CD2 . PHE A 1 14  ? -18.05500 -8.52236  -1.27550  1.000 359.58829 ? 20  PHE e CD2 1 
ATOM 119  C CE1 . PHE A 1 14  ? -15.63400 -7.28436  -1.76650  1.000 359.58829 ? 20  PHE e CE1 1 
ATOM 120  C CE2 . PHE A 1 14  ? -16.87400 -9.21836  -1.09050  1.000 359.58829 ? 20  PHE e CE2 1 
ATOM 121  C CZ  . PHE A 1 14  ? -15.66300 -8.59736  -1.33550  1.000 359.58829 ? 20  PHE e CZ  1 
ATOM 122  N N   . ALA A 1 15  ? -18.86900 -8.01036  -4.88550  1.000 355.44451 ? 21  ALA e N   1 
ATOM 123  C CA  . ALA A 1 15  ? -18.82400 -9.36336  -5.43850  1.000 355.44451 ? 21  ALA e CA  1 
ATOM 124  C C   . ALA A 1 15  ? -17.40600 -9.70736  -5.87850  1.000 355.44451 ? 21  ALA e C   1 
ATOM 125  O O   . ALA A 1 15  ? -17.00900 -9.34036  -6.99050  1.000 355.44451 ? 21  ALA e O   1 
ATOM 126  C CB  . ALA A 1 15  ? -19.78400 -9.50136  -6.62750  1.000 355.44451 ? 21  ALA e CB  1 
ATOM 127  N N   . GLU A 1 16  ? -16.67100 -10.45736 -5.03950  1.000 333.32848 ? 22  GLU e N   1 
ATOM 128  C CA  . GLU A 1 16  ? -15.34400 -10.99236 -5.36750  1.000 333.32848 ? 22  GLU e CA  1 
ATOM 129  C C   . GLU A 1 16  ? -14.90600 -12.02036 -4.32550  1.000 333.32848 ? 22  GLU e C   1 
ATOM 130  O O   . GLU A 1 16  ? -15.17600 -11.83036 -3.13650  1.000 333.32848 ? 22  GLU e O   1 
ATOM 131  C CB  . GLU A 1 16  ? -14.29800 -9.87336  -5.43950  1.000 333.32848 ? 22  GLU e CB  1 
ATOM 132  C CG  . GLU A 1 16  ? -13.00300 -10.24436 -6.15150  1.000 333.32848 ? 22  GLU e CG  1 
ATOM 133  C CD  . GLU A 1 16  ? -12.10900 -9.03436  -6.38150  1.000 333.32848 ? 22  GLU e CD  1 
ATOM 134  O OE1 . GLU A 1 16  ? -12.50300 -7.92436  -5.97050  1.000 333.32848 ? 22  GLU e OE1 1 
ATOM 135  O OE2 . GLU A 1 16  ? -11.01600 -9.18436  -6.97050  1.000 333.32848 ? 22  GLU e OE2 1 
ATOM 136  N N   . ASP A 1 17  ? -14.20100 -13.08236 -4.74050  1.000 253.05259 ? 23  ASP e N   1 
ATOM 137  C CA  . ASP A 1 17  ? -13.74700 -14.11736 -3.80850  1.000 253.05259 ? 23  ASP e CA  1 
ATOM 138  C C   . ASP A 1 17  ? -12.58000 -14.96536 -4.31850  1.000 253.05259 ? 23  ASP e C   1 
ATOM 139  O O   . ASP A 1 17  ? -12.62400 -15.49136 -5.43350  1.000 253.05259 ? 23  ASP e O   1 
ATOM 140  C CB  . ASP A 1 17  ? -14.91800 -15.03536 -3.43450  1.000 253.05259 ? 23  ASP e CB  1 
ATOM 141  C CG  . ASP A 1 17  ? -15.67800 -15.54236 -4.64050  1.000 253.05259 ? 23  ASP e CG  1 
ATOM 142  O OD1 . ASP A 1 17  ? -15.40000 -15.10936 -5.77950  1.000 253.05259 ? 23  ASP e OD1 1 
ATOM 143  O OD2 . ASP A 1 17  ? -16.57400 -16.38136 -4.44050  1.000 253.05259 ? 23  ASP e OD2 1 
ATOM 144  N N   . VAL A 1 18  ? -11.56000 -15.13036 -3.47150  1.000 326.89252 ? 24  VAL e N   1 
ATOM 145  C CA  . VAL A 1 18  ? -10.39400 -15.97436 -3.75450  1.000 326.89252 ? 24  VAL e CA  1 
ATOM 146  C C   . VAL A 1 18  ? -9.91300  -16.55036 -2.42250  1.000 326.89252 ? 24  VAL e C   1 
ATOM 147  O O   . VAL A 1 18  ? -9.85200  -15.83736 -1.41750  1.000 326.89252 ? 24  VAL e O   1 
ATOM 148  C CB  . VAL A 1 18  ? -9.28600  -15.13736 -4.46150  1.000 326.89252 ? 24  VAL e CB  1 
ATOM 149  C CG1 . VAL A 1 18  ? -7.89400  -15.70736 -4.27750  1.000 326.89252 ? 24  VAL e CG1 1 
ATOM 150  C CG2 . VAL A 1 18  ? -9.50400  -15.02736 -5.96350  1.000 326.89252 ? 24  VAL e CG2 1 
ATOM 151  N N   . GLY A 1 19  ? -9.53000  -17.82936 -2.41350  1.000 439.32268 ? 25  GLY e N   1 
ATOM 152  C CA  . GLY A 1 19  ? -9.07200  -18.41236 -1.16050  1.000 439.32268 ? 25  GLY e CA  1 
ATOM 153  C C   . GLY A 1 19  ? -8.32100  -19.71536 -1.34950  1.000 439.32268 ? 25  GLY e C   1 
ATOM 154  O O   . GLY A 1 19  ? -8.30200  -20.30236 -2.43750  1.000 439.32268 ? 25  GLY e O   1 
ATOM 155  N N   . SER A 1 20  ? -7.69700  -20.15536 -0.24850  1.000 451.56161 ? 26  SER e N   1 
ATOM 156  C CA  . SER A 1 20  ? -6.91800  -21.39336 -0.16550  1.000 451.56161 ? 26  SER e CA  1 
ATOM 157  C C   . SER A 1 20  ? -6.79600  -21.78736 1.30350   1.000 451.56161 ? 26  SER e C   1 
ATOM 158  O O   . SER A 1 20  ? -6.35000  -20.97736 2.12250   1.000 451.56161 ? 26  SER e O   1 
ATOM 159  C CB  . SER A 1 20  ? -5.53000  -21.21836 -0.79250  1.000 451.56161 ? 26  SER e CB  1 
ATOM 160  O OG  . SER A 1 20  ? -4.62000  -20.65036 0.13450   1.000 451.56161 ? 26  SER e OG  1 
ATOM 161  N N   . ASN A 1 21  ? -7.18500  -23.01336 1.64350   1.000 361.50558 ? 27  ASN e N   1 
ATOM 162  C CA  . ASN A 1 21  ? -7.27300  -23.43636 3.04650   1.000 361.50558 ? 27  ASN e CA  1 
ATOM 163  C C   . ASN A 1 21  ? -7.01400  -24.94136 3.16350   1.000 361.50558 ? 27  ASN e C   1 
ATOM 164  O O   . ASN A 1 21  ? -6.34500  -25.54536 2.31450   1.000 361.50558 ? 27  ASN e O   1 
ATOM 165  C CB  . ASN A 1 21  ? -8.61300  -22.96536 3.66350   1.000 361.50558 ? 27  ASN e CB  1 
ATOM 166  C CG  . ASN A 1 21  ? -9.86000  -23.63236 3.04750   1.000 361.50558 ? 27  ASN e CG  1 
ATOM 167  O OD1 . ASN A 1 21  ? -9.78600  -24.43936 2.12750   1.000 361.50558 ? 27  ASN e OD1 1 
ATOM 168  N ND2 . ASN A 1 21  ? -11.01800 -23.27836 3.57650   1.000 361.50558 ? 27  ASN e ND2 1 
ATOM 169  N N   . LYS A 1 22  ? -7.47100  -25.50736 4.29350   1.000 348.81850 ? 28  LYS e N   1 
ATOM 170  C CA  . LYS A 1 22  ? -7.59300  -26.93736 4.60250   1.000 348.81850 ? 28  LYS e CA  1 
ATOM 171  C C   . LYS A 1 22  ? -6.26000  -27.61436 4.89650   1.000 348.81850 ? 28  LYS e C   1 
ATOM 172  O O   . LYS A 1 22  ? -6.08600  -28.79436 4.58950   1.000 348.81850 ? 28  LYS e O   1 
ATOM 173  C CB  . LYS A 1 22  ? -8.34200  -27.71136 3.50450   1.000 348.81850 ? 28  LYS e CB  1 
ATOM 174  C CG  . LYS A 1 22  ? -9.86100  -27.68836 3.62550   1.000 348.81850 ? 28  LYS e CG  1 
ATOM 175  C CD  . LYS A 1 22  ? -10.51000 -27.98436 2.27950   1.000 348.81850 ? 28  LYS e CD  1 
ATOM 176  C CE  . LYS A 1 22  ? -10.24400 -29.42236 1.84950   1.000 348.81850 ? 28  LYS e CE  1 
ATOM 177  N NZ  . LYS A 1 22  ? -11.03200 -30.39636 2.65850   1.000 348.81850 ? 28  LYS e NZ  1 
ATOM 178  N N   . GLY A 1 23  ? -5.30800  -26.89836 5.49750   1.000 488.31265 ? 29  GLY e N   1 
ATOM 179  C CA  . GLY A 1 23  ? -4.07600  -27.53236 5.93450   1.000 488.31265 ? 29  GLY e CA  1 
ATOM 180  C C   . GLY A 1 23  ? -4.14000  -28.15536 7.31350   1.000 488.31265 ? 29  GLY e C   1 
ATOM 181  O O   . GLY A 1 23  ? -3.39100  -29.09736 7.59150   1.000 488.31265 ? 29  GLY e O   1 
ATOM 182  N N   . ALA A 1 24  ? -5.00400  -27.64136 8.19050   1.000 499.62028 ? 30  ALA e N   1 
ATOM 183  C CA  . ALA A 1 24  ? -5.10700  -28.18736 9.53750   1.000 499.62028 ? 30  ALA e CA  1 
ATOM 184  C C   . ALA A 1 24  ? -5.86500  -29.50136 9.55550   1.000 499.62028 ? 30  ALA e C   1 
ATOM 185  O O   . ALA A 1 24  ? -5.54800  -30.38536 10.35750  1.000 499.62028 ? 30  ALA e O   1 
ATOM 186  C CB  . ALA A 1 24  ? -5.79200  -27.18836 10.46750  1.000 499.62028 ? 30  ALA e CB  1 
ATOM 187  N N   . ILE A 1 25  ? -6.85200  -29.64836 8.67250   1.000 403.12017 ? 31  ILE e N   1 
ATOM 188  C CA  . ILE A 1 25  ? -7.57500  -30.90436 8.56050   1.000 403.12017 ? 31  ILE e CA  1 
ATOM 189  C C   . ILE A 1 25  ? -6.69400  -31.98536 7.94450   1.000 403.12017 ? 31  ILE e C   1 
ATOM 190  O O   . ILE A 1 25  ? -6.91000  -33.17736 8.20550   1.000 403.12017 ? 31  ILE e O   1 
ATOM 191  C CB  . ILE A 1 25  ? -8.87400  -30.64736 7.77250   1.000 403.12017 ? 31  ILE e CB  1 
ATOM 192  C CG1 . ILE A 1 25  ? -9.79700  -31.86436 7.78950   1.000 403.12017 ? 31  ILE e CG1 1 
ATOM 193  C CG2 . ILE A 1 25  ? -8.58200  -30.18636 6.34850   1.000 403.12017 ? 31  ILE e CG2 1 
ATOM 194  C CD1 . ILE A 1 25  ? -10.22900 -32.24736 9.17550   1.000 403.12017 ? 31  ILE e CD1 1 
ATOM 195  N N   . ILE A 1 26  ? -5.68300  -31.58636 7.16250   1.000 402.64463 ? 32  ILE e N   1 
ATOM 196  C CA  . ILE A 1 26  ? -4.65400  -32.51236 6.70350   1.000 402.64463 ? 32  ILE e CA  1 
ATOM 197  C C   . ILE A 1 26  ? -3.93000  -33.11436 7.89450   1.000 402.64463 ? 32  ILE e C   1 
ATOM 198  O O   . ILE A 1 26  ? -3.77300  -34.33736 7.99450   1.000 402.64463 ? 32  ILE e O   1 
ATOM 199  C CB  . ILE A 1 26  ? -3.67900  -31.78836 5.75650   1.000 402.64463 ? 32  ILE e CB  1 
ATOM 200  C CG1 . ILE A 1 26  ? -4.33200  -31.53536 4.39950   1.000 402.64463 ? 32  ILE e CG1 1 
ATOM 201  C CG2 . ILE A 1 26  ? -2.38500  -32.56836 5.59650   1.000 402.64463 ? 32  ILE e CG2 1 
ATOM 202  C CD1 . ILE A 1 26  ? -4.83100  -32.78336 3.72650   1.000 402.64463 ? 32  ILE e CD1 1 
ATOM 203  N N   . GLY A 1 27  ? -3.52100  -32.26836 8.83950   1.000 378.86784 ? 33  GLY e N   1 
ATOM 204  C CA  . GLY A 1 27  ? -2.98200  -32.76736 10.08650  1.000 378.86784 ? 33  GLY e CA  1 
ATOM 205  C C   . GLY A 1 27  ? -3.99700  -33.49536 10.93650  1.000 378.86784 ? 33  GLY e C   1 
ATOM 206  O O   . GLY A 1 27  ? -3.63100  -34.43736 11.64450  1.000 378.86784 ? 33  GLY e O   1 
ATOM 207  N N   . LEU A 1 28  ? -5.27200  -33.11436 10.85050  1.000 451.57242 ? 34  LEU e N   1 
ATOM 208  C CA  . LEU A 1 28  ? -6.30200  -33.84236 11.57550  1.000 451.57242 ? 34  LEU e CA  1 
ATOM 209  C C   . LEU A 1 28  ? -6.63300  -35.16736 10.91950  1.000 451.57242 ? 34  LEU e C   1 
ATOM 210  O O   . LEU A 1 28  ? -7.24800  -36.02536 11.55750  1.000 451.57242 ? 34  LEU e O   1 
ATOM 211  C CB  . LEU A 1 28  ? -7.56900  -33.00336 11.69050  1.000 451.57242 ? 34  LEU e CB  1 
ATOM 212  C CG  . LEU A 1 28  ? -7.45400  -31.83836 12.66350  1.000 451.57242 ? 34  LEU e CG  1 
ATOM 213  C CD1 . LEU A 1 28  ? -8.52300  -30.81036 12.36750  1.000 451.57242 ? 34  LEU e CD1 1 
ATOM 214  C CD2 . LEU A 1 28  ? -7.56200  -32.34436 14.09150  1.000 451.57242 ? 34  LEU e CD2 1 
ATOM 215  N N   . MET A 1 29  ? -6.23800  -35.34736 9.66550   1.000 404.13090 ? 35  MET e N   1 
ATOM 216  C CA  . MET A 1 29  ? -6.39800  -36.62636 9.00150   1.000 404.13090 ? 35  MET e CA  1 
ATOM 217  C C   . MET A 1 29  ? -5.11700  -37.43736 9.00150   1.000 404.13090 ? 35  MET e C   1 
ATOM 218  O O   . MET A 1 29  ? -5.17800  -38.67136 8.95750   1.000 404.13090 ? 35  MET e O   1 
ATOM 219  C CB  . MET A 1 29  ? -6.89600  -36.40736 7.57950   1.000 404.13090 ? 35  MET e CB  1 
ATOM 220  C CG  . MET A 1 29  ? -8.37700  -36.10836 7.54150   1.000 404.13090 ? 35  MET e CG  1 
ATOM 221  S SD  . MET A 1 29  ? -9.28600  -37.14236 8.70850   1.000 404.13090 ? 35  MET e SD  1 
ATOM 222  C CE  . MET A 1 29  ? -10.00100 -35.90936 9.78850   1.000 404.13090 ? 35  MET e CE  1 
ATOM 223  N N   . VAL A 1 30  ? -3.96000  -36.77336 9.04450   1.000 304.24708 ? 36  VAL e N   1 
ATOM 224  C CA  . VAL A 1 30  ? -2.76600  -37.44836 9.53650   1.000 304.24708 ? 36  VAL e CA  1 
ATOM 225  C C   . VAL A 1 30  ? -3.00600  -37.88836 10.97050  1.000 304.24708 ? 36  VAL e C   1 
ATOM 226  O O   . VAL A 1 30  ? -2.67300  -39.01736 11.34950  1.000 304.24708 ? 36  VAL e O   1 
ATOM 227  C CB  . VAL A 1 30  ? -1.53400  -36.53236 9.40750   1.000 304.24708 ? 36  VAL e CB  1 
ATOM 228  C CG1 . VAL A 1 30  ? -0.34000  -37.10536 10.15950  1.000 304.24708 ? 36  VAL e CG1 1 
ATOM 229  C CG2 . VAL A 1 30  ? -1.17600  -36.34236 7.95050   1.000 304.24708 ? 36  VAL e CG2 1 
ATOM 230  N N   . GLY A 1 31  ? -3.65100  -37.03636 11.76450  1.000 334.27262 ? 37  GLY e N   1 
ATOM 231  C CA  . GLY A 1 31  ? -4.19500  -37.36136 13.06350  1.000 334.27262 ? 37  GLY e CA  1 
ATOM 232  C C   . GLY A 1 31  ? -5.51400  -38.09536 13.04350  1.000 334.27262 ? 37  GLY e C   1 
ATOM 233  O O   . GLY A 1 31  ? -6.17400  -38.20336 14.08050  1.000 334.27262 ? 37  GLY e O   1 
ATOM 234  N N   . GLY A 1 32  ? -5.93700  -38.59036 11.88050  1.000 393.71007 ? 38  GLY e N   1 
ATOM 235  C CA  . GLY A 1 32  ? -7.07700  -39.48036 11.82750  1.000 393.71007 ? 38  GLY e CA  1 
ATOM 236  C C   . GLY A 1 32  ? -6.77100  -40.88536 12.30150  1.000 393.71007 ? 38  GLY e C   1 
ATOM 237  O O   . GLY A 1 32  ? -7.69300  -41.69336 12.44050  1.000 393.71007 ? 38  GLY e O   1 
ATOM 238  N N   . VAL A 1 33  ? -5.50200  -41.19236 12.55850  1.000 376.34856 ? 39  VAL e N   1 
ATOM 239  C CA  . VAL A 1 33  ? -5.14400  -42.52336 13.02650  1.000 376.34856 ? 39  VAL e CA  1 
ATOM 240  C C   . VAL A 1 33  ? -5.25400  -42.64936 14.55050  1.000 376.34856 ? 39  VAL e C   1 
ATOM 241  O O   . VAL A 1 33  ? -5.74400  -43.66736 15.04850  1.000 376.34856 ? 39  VAL e O   1 
ATOM 242  C CB  . VAL A 1 33  ? -3.73800  -42.90536 12.50550  1.000 376.34856 ? 39  VAL e CB  1 
ATOM 243  C CG1 . VAL A 1 33  ? -2.66500  -41.89336 12.90050  1.000 376.34856 ? 39  VAL e CG1 1 
ATOM 244  C CG2 . VAL A 1 33  ? -3.34100  -44.29636 12.95950  1.000 376.34856 ? 39  VAL e CG2 1 
ATOM 245  N N   . VAL A 1 34  ? -4.86000  -41.62636 15.31050  1.000 362.33465 ? 40  VAL e N   1 
ATOM 246  C CA  . VAL A 1 34  ? -4.84700  -41.67336 16.77150  1.000 362.33465 ? 40  VAL e CA  1 
ATOM 247  C C   . VAL A 1 34  ? -5.43500  -40.37036 17.29550  1.000 362.33465 ? 40  VAL e C   1 
ATOM 248  O O   . VAL A 1 34  ? -4.88300  -39.29436 17.04850  1.000 362.33465 ? 40  VAL e O   1 
ATOM 249  C CB  . VAL A 1 34  ? -3.42500  -41.86436 17.34750  1.000 362.33465 ? 40  VAL e CB  1 
ATOM 250  C CG1 . VAL A 1 34  ? -3.44600  -41.73536 18.86950  1.000 362.33465 ? 40  VAL e CG1 1 
ATOM 251  C CG2 . VAL A 1 34  ? -2.80500  -43.19336 16.92650  1.000 362.33465 ? 40  VAL e CG2 1 
ATOM 252  N N   . ILE A 1 35  ? -6.55200  -40.45536 18.01550  1.000 299.30988 ? 41  ILE e N   1 
ATOM 253  C CA  . ILE A 1 35  ? -7.11700  -39.28936 18.67850  1.000 299.30988 ? 41  ILE e CA  1 
ATOM 254  C C   . ILE A 1 35  ? -7.36900  -39.52836 20.15850  1.000 299.30988 ? 41  ILE e C   1 
ATOM 255  O O   . ILE A 1 35  ? -7.49500  -38.56336 20.91550  1.000 299.30988 ? 41  ILE e O   1 
ATOM 256  C CB  . ILE A 1 35  ? -8.40100  -38.80936 17.96750  1.000 299.30988 ? 41  ILE e CB  1 
ATOM 257  C CG1 . ILE A 1 35  ? -8.56400  -37.29536 18.11450  1.000 299.30988 ? 41  ILE e CG1 1 
ATOM 258  C CG2 . ILE A 1 35  ? -9.63500  -39.53636 18.48050  1.000 299.30988 ? 41  ILE e CG2 1 
ATOM 259  C CD1 . ILE A 1 35  ? -7.48400  -36.50536 17.41450  1.000 299.30988 ? 41  ILE e CD1 1 
ATOM 260  N N   . ALA A 1 36  ? -7.40000  -40.77936 20.60250  1.000 346.46690 ? 42  ALA e N   1 
ATOM 261  C CA  . ALA A 1 36  ? -7.60900  -41.07836 22.00850  1.000 346.46690 ? 42  ALA e CA  1 
ATOM 262  C C   . ALA A 1 36  ? -6.26800  -41.18636 22.71050  1.000 346.46690 ? 42  ALA e C   1 
ATOM 263  O O   . ALA A 1 36  ? -6.16900  -41.75136 23.79650  1.000 346.46690 ? 42  ALA e O   1 
ATOM 264  C CB  . ALA A 1 36  ? -8.40500  -42.35636 22.17350  1.000 346.46690 ? 42  ALA e CB  1 
ATOM 265  O OXT . ALA A 1 36  ? -5.25400  -40.71536 22.19850  1.000 346.46690 ? 42  ALA e OXT 1 
ATOM 266  N N   . GLY B 2 1   ? 5.63300   -17.14036 -13.69750 0.500 401.82673 ? 1   GLY b N   1 
ATOM 267  C CA  . GLY B 2 1   ? 5.05000   -18.00936 -14.70250 0.500 401.82673 ? 1   GLY b CA  1 
ATOM 268  C C   . GLY B 2 1   ? 5.65800   -17.82436 -16.07850 0.500 401.82673 ? 1   GLY b C   1 
ATOM 269  O O   . GLY B 2 1   ? 6.83900   -18.11736 -16.27850 0.500 401.82673 ? 1   GLY b O   1 
ATOM 270  N N   . PRO B 2 2   ? 4.85800   -17.34436 -17.03250 0.500 415.75881 ? 2   PRO b N   1 
ATOM 271  C CA  . PRO B 2 2   ? 5.38100   -17.10636 -18.38550 0.500 415.75881 ? 2   PRO b CA  1 
ATOM 272  C C   . PRO B 2 2   ? 6.30800   -15.90136 -18.37950 0.500 415.75881 ? 2   PRO b C   1 
ATOM 273  O O   . PRO B 2 2   ? 5.85900   -14.75336 -18.38150 0.500 415.75881 ? 2   PRO b O   1 
ATOM 274  C CB  . PRO B 2 2   ? 4.12000   -16.84736 -19.22050 0.500 415.75881 ? 2   PRO b CB  1 
ATOM 275  C CG  . PRO B 2 2   ? 2.96700   -17.28736 -18.35850 0.500 415.75881 ? 2   PRO b CG  1 
ATOM 276  C CD  . PRO B 2 2   ? 3.41700   -17.05636 -16.95250 0.500 415.75881 ? 2   PRO b CD  1 
ATOM 277  N N   . THR B 2 3   ? 7.60400   -16.17336 -18.36550 0.500 434.82590 ? 3   THR b N   1 
ATOM 278  C CA  . THR B 2 3   ? 8.59800   -15.11836 -18.34550 0.500 434.82590 ? 3   THR b CA  1 
ATOM 279  C C   . THR B 2 3   ? 8.73800   -14.54236 -19.74450 0.500 434.82590 ? 3   THR b C   1 
ATOM 280  O O   . THR B 2 3   ? 8.75900   -15.27636 -20.73650 0.500 434.82590 ? 3   THR b O   1 
ATOM 281  C CB  . THR B 2 3   ? 9.94200   -15.64636 -17.84750 0.500 434.82590 ? 3   THR b CB  1 
ATOM 282  O OG1 . THR B 2 3   ? 10.50600  -16.52336 -18.82950 0.500 434.82590 ? 3   THR b OG1 1 
ATOM 283  C CG2 . THR B 2 3   ? 9.75900   -16.40936 -16.54350 0.500 434.82590 ? 3   THR b CG2 1 
ATOM 284  N N   . GLY B 2 4   ? 8.81400   -13.22036 -19.81750 0.500 482.71343 ? 4   GLY b N   1 
ATOM 285  C CA  . GLY B 2 4   ? 8.91700   -12.54936 -21.09250 0.500 482.71343 ? 4   GLY b CA  1 
ATOM 286  C C   . GLY B 2 4   ? 7.56900   -12.33636 -21.74150 0.500 482.71343 ? 4   GLY b C   1 
ATOM 287  O O   . GLY B 2 4   ? 7.08800   -11.20336 -21.82350 0.500 482.71343 ? 4   GLY b O   1 
ATOM 288  N N   . THR B 2 5   ? 6.93500   -13.41336 -22.19150 0.500 474.36913 ? 5   THR b N   1 
ATOM 289  C CA  . THR B 2 5   ? 5.70500   -13.28736 -22.95150 0.500 474.36913 ? 5   THR b CA  1 
ATOM 290  C C   . THR B 2 5   ? 4.71900   -14.35836 -22.51250 0.500 474.36913 ? 5   THR b C   1 
ATOM 291  O O   . THR B 2 5   ? 5.04900   -15.54536 -22.45650 0.500 474.36913 ? 5   THR b O   1 
ATOM 292  C CB  . THR B 2 5   ? 5.98100   -13.39336 -24.45750 0.500 474.36913 ? 5   THR b CB  1 
ATOM 293  O OG1 . THR B 2 5   ? 6.95800   -12.41336 -24.83050 0.500 474.36913 ? 5   THR b OG1 1 
ATOM 294  C CG2 . THR B 2 5   ? 4.71300   -13.15636 -25.25850 0.500 474.36913 ? 5   THR b CG2 1 
ATOM 295  N N   . GLY B 2 6   ? 3.50600   -13.92236 -22.20150 0.500 458.02419 ? 6   GLY b N   1 
ATOM 296  C CA  . GLY B 2 6   ? 2.45300   -14.84636 -21.84250 0.500 458.02419 ? 6   GLY b CA  1 
ATOM 297  C C   . GLY B 2 6   ? 1.18200   -14.08936 -21.51950 0.500 458.02419 ? 6   GLY b C   1 
ATOM 298  O O   . GLY B 2 6   ? 1.14700   -12.85536 -21.53250 0.500 458.02419 ? 6   GLY b O   1 
ATOM 299  N N   . GLU B 2 7   ? 0.14300   -14.85536 -21.20950 0.500 470.96026 ? 7   GLU b N   1 
ATOM 300  C CA  . GLU B 2 7   ? -1.20400  -14.30736 -21.12250 0.500 470.96026 ? 7   GLU b CA  1 
ATOM 301  C C   . GLU B 2 7   ? -1.88300  -14.81636 -19.85550 0.500 470.96026 ? 7   GLU b C   1 
ATOM 302  O O   . GLU B 2 7   ? -2.97500  -15.38736 -19.87750 0.500 470.96026 ? 7   GLU b O   1 
ATOM 303  C CB  . GLU B 2 7   ? -1.98400  -14.64636 -22.39050 0.500 470.96026 ? 7   GLU b CB  1 
ATOM 304  C CG  . GLU B 2 7   ? -3.18300  -13.75536 -22.63150 0.500 470.96026 ? 7   GLU b CG  1 
ATOM 305  C CD  . GLU B 2 7   ? -3.71500  -13.86836 -24.02750 0.500 470.96026 ? 7   GLU b CD  1 
ATOM 306  O OE1 . GLU B 2 7   ? -4.67700  -14.63036 -24.23750 0.500 470.96026 ? 7   GLU b OE1 1 
ATOM 307  O OE2 . GLU B 2 7   ? -3.16800  -13.19736 -24.92350 0.500 470.96026 ? 7   GLU b OE2 1 
ATOM 308  N N   . SER B 2 8   ? -1.20300  -14.64036 -18.72350 0.500 520.10378 ? 8   SER b N   1 
ATOM 309  C CA  . SER B 2 8   ? -1.76300  -15.05436 -17.44150 0.500 520.10378 ? 8   SER b CA  1 
ATOM 310  C C   . SER B 2 8   ? -2.87400  -14.10936 -17.00150 0.500 520.10378 ? 8   SER b C   1 
ATOM 311  O O   . SER B 2 8   ? -3.95200  -14.54036 -16.57450 0.500 520.10378 ? 8   SER b O   1 
ATOM 312  C CB  . SER B 2 8   ? -0.65700  -15.10836 -16.38850 0.500 520.10378 ? 8   SER b CB  1 
ATOM 313  O OG  . SER B 2 8   ? -0.04300  -13.83636 -16.25050 0.500 520.10378 ? 8   SER b OG  1 
ATOM 314  N N   . LYS B 2 9   ? -2.62600  -12.80636 -17.12050 0.500 501.02029 ? 9   LYS b N   1 
ATOM 315  C CA  . LYS B 2 9   ? -3.54200  -11.77136 -16.66450 0.500 501.02029 ? 9   LYS b CA  1 
ATOM 316  C C   . LYS B 2 9   ? -4.49100  -11.33836 -17.76950 0.500 501.02029 ? 9   LYS b C   1 
ATOM 317  O O   . LYS B 2 9   ? -5.27500  -10.40236 -17.57450 0.500 501.02029 ? 9   LYS b O   1 
ATOM 318  C CB  . LYS B 2 9   ? -2.75000  -10.56536 -16.16450 0.500 501.02029 ? 9   LYS b CB  1 
ATOM 319  C CG  . LYS B 2 9   ? -1.78300  -10.03436 -17.21650 0.500 501.02029 ? 9   LYS b CG  1 
ATOM 320  C CD  . LYS B 2 9   ? -0.78000  -9.05536  -16.63850 0.500 501.02029 ? 9   LYS b CD  1 
ATOM 321  C CE  . LYS B 2 9   ? 0.22400   -8.61736  -17.69250 0.500 501.02029 ? 9   LYS b CE  1 
ATOM 322  N NZ  . LYS B 2 9   ? 1.29800   -7.77536  -17.10150 0.500 501.02029 ? 9   LYS b NZ  1 
ATOM 323  N N   . ARG B 2 10  ? -4.43600  -12.02636 -18.91550 1.000 531.33696 ? 10  ARG b N   1 
ATOM 324  C CA  . ARG B 2 10  ? -5.03400  -11.65836 -20.19350 1.000 531.33696 ? 10  ARG b CA  1 
ATOM 325  C C   . ARG B 2 10  ? -4.71800  -10.20436 -20.53450 1.000 531.33696 ? 10  ARG b C   1 
ATOM 326  O O   . ARG B 2 10  ? -5.59800  -9.34736  -20.40850 1.000 531.33696 ? 10  ARG b O   1 
ATOM 327  C CB  . ARG B 2 10  ? -6.54600  -11.89736 -20.18750 1.000 531.33696 ? 10  ARG b CB  1 
ATOM 328  C CG  . ARG B 2 10  ? -6.98500  -13.29236 -20.61750 1.000 531.33696 ? 10  ARG b CG  1 
ATOM 329  C CD  . ARG B 2 10  ? -6.88300  -13.46236 -22.12550 1.000 531.33696 ? 10  ARG b CD  1 
ATOM 330  N NE  . ARG B 2 10  ? -7.33600  -12.29136 -22.87550 1.000 531.33696 ? 10  ARG b NE  1 
ATOM 331  C CZ  . ARG B 2 10  ? -8.55300  -12.15136 -23.39250 1.000 531.33696 ? 10  ARG b CZ  1 
ATOM 332  N NH1 . ARG B 2 10  ? -9.44900  -13.11836 -23.26650 1.000 531.33696 ? 10  ARG b NH1 1 
ATOM 333  N NH2 . ARG B 2 10  ? -8.86900  -11.04936 -24.05850 1.000 531.33696 ? 10  ARG b NH2 1 
ATOM 334  N N   . PRO B 2 11  ? -3.48000  -9.86336  -20.91150 1.000 554.22819 ? 11  PRO b N   1 
ATOM 335  C CA  . PRO B 2 11  ? -3.20800  -8.46336  -21.26550 1.000 554.22819 ? 11  PRO b CA  1 
ATOM 336  C C   . PRO B 2 11  ? -3.88400  -8.00336  -22.55450 1.000 554.22819 ? 11  PRO b C   1 
ATOM 337  O O   . PRO B 2 11  ? -4.47600  -6.91836  -22.53750 1.000 554.22819 ? 11  PRO b O   1 
ATOM 338  C CB  . PRO B 2 11  ? -1.67700  -8.41236  -21.36350 1.000 554.22819 ? 11  PRO b CB  1 
ATOM 339  C CG  . PRO B 2 11  ? -1.27200  -9.80236  -21.61950 1.000 554.22819 ? 11  PRO b CG  1 
ATOM 340  C CD  . PRO B 2 11  ? -2.24300  -10.66436 -20.90050 1.000 554.22819 ? 11  PRO b CD  1 
ATOM 341  N N   . LEU B 2 12  ? -3.87900  -8.78636  -23.64150 1.000 673.51717 ? 12  LEU b N   1 
ATOM 342  C CA  . LEU B 2 12  ? -4.47100  -8.29636  -24.89350 1.000 673.51717 ? 12  LEU b CA  1 
ATOM 343  C C   . LEU B 2 12  ? -4.89400  -9.44736  -25.80650 1.000 673.51717 ? 12  LEU b C   1 
ATOM 344  O O   . LEU B 2 12  ? -4.03900  -10.13636 -26.36850 1.000 673.51717 ? 12  LEU b O   1 
ATOM 345  C CB  . LEU B 2 12  ? -3.48600  -7.36936  -25.59950 1.000 673.51717 ? 12  LEU b CB  1 
ATOM 346  C CG  . LEU B 2 12  ? -3.87500  -6.61736  -26.86750 1.000 673.51717 ? 12  LEU b CG  1 
ATOM 347  C CD1 . LEU B 2 12  ? -5.11400  -5.78636  -26.65550 1.000 673.51717 ? 12  LEU b CD1 1 
ATOM 348  C CD2 . LEU B 2 12  ? -2.72700  -5.70136  -27.18850 1.000 673.51717 ? 12  LEU b CD2 1 
ATOM 349  N N   . MET B 2 13  ? -6.21000  -9.63636  -25.97350 1.000 653.10354 ? 13  MET b N   1 
ATOM 350  C CA  . MET B 2 13  ? -6.75000  -10.55836 -26.98050 1.000 653.10354 ? 13  MET b CA  1 
ATOM 351  C C   . MET B 2 13  ? -8.16600  -10.11036 -27.33350 1.000 653.10354 ? 13  MET b C   1 
ATOM 352  O O   . MET B 2 13  ? -9.09600  -10.34536 -26.55550 1.000 653.10354 ? 13  MET b O   1 
ATOM 353  C CB  . MET B 2 13  ? -6.74800  -11.99536 -26.48550 1.000 653.10354 ? 13  MET b CB  1 
ATOM 354  C CG  . MET B 2 13  ? -7.12400  -12.99636 -27.55550 1.000 653.10354 ? 13  MET b CG  1 
ATOM 355  S SD  . MET B 2 13  ? -8.13700  -14.33836 -26.90850 1.000 653.10354 ? 13  MET b SD  1 
ATOM 356  C CE  . MET B 2 13  ? -9.73600  -13.54436 -26.78150 1.000 653.10354 ? 13  MET b CE  1 
ATOM 357  N N   . VAL B 2 14  ? -8.33000  -9.49336  -28.50550 1.000 434.92115 ? 14  VAL b N   1 
ATOM 358  C CA  . VAL B 2 14  ? -9.60500  -8.88636  -28.86150 1.000 434.92115 ? 14  VAL b CA  1 
ATOM 359  C C   . VAL B 2 14  ? -9.68700  -8.68536  -30.37250 1.000 434.92115 ? 14  VAL b C   1 
ATOM 360  O O   . VAL B 2 14  ? -8.67900  -8.75136  -31.08250 1.000 434.92115 ? 14  VAL b O   1 
ATOM 361  C CB  . VAL B 2 14  ? -9.78000  -7.55136  -28.10150 1.000 434.92115 ? 14  VAL b CB  1 
ATOM 362  C CG1 . VAL B 2 14  ? -9.08400  -6.38836  -28.81750 1.000 434.92115 ? 14  VAL b CG1 1 
ATOM 363  C CG2 . VAL B 2 14  ? -11.21400 -7.30036  -27.76850 1.000 434.92115 ? 14  VAL b CG2 1 
ATOM 364  N N   . LYS B 2 15  ? -10.90600 -8.46136  -30.86650 1.000 460.96101 ? 15  LYS b N   1 
ATOM 365  C CA  . LYS B 2 15  ? -11.15000 -8.07936  -32.25250 1.000 460.96101 ? 15  LYS b CA  1 
ATOM 366  C C   . LYS B 2 15  ? -11.28700 -6.56336  -32.35450 1.000 460.96101 ? 15  LYS b C   1 
ATOM 367  O O   . LYS B 2 15  ? -12.03600 -5.94936  -31.58850 1.000 460.96101 ? 15  LYS b O   1 
ATOM 368  C CB  . LYS B 2 15  ? -12.40700 -8.76136  -32.79150 1.000 460.96101 ? 15  LYS b CB  1 
ATOM 369  C CG  . LYS B 2 15  ? -12.98400 -8.10536  -34.03150 1.000 460.96101 ? 15  LYS b CG  1 
ATOM 370  C CD  . LYS B 2 15  ? -14.35000 -8.65136  -34.35750 1.000 460.96101 ? 15  LYS b CD  1 
ATOM 371  C CE  . LYS B 2 15  ? -15.04000 -7.77336  -35.37350 1.000 460.96101 ? 15  LYS b CE  1 
ATOM 372  N NZ  . LYS B 2 15  ? -14.25900 -7.68436  -36.63950 1.000 460.96101 ? 15  LYS b NZ  1 
ATOM 373  N N   . VAL B 2 16  ? -10.55700 -5.96536  -33.30050 1.000 620.63746 ? 16  VAL b N   1 
ATOM 374  C CA  . VAL B 2 16  ? -10.44900 -4.51636  -33.44450 1.000 620.63746 ? 16  VAL b CA  1 
ATOM 375  C C   . VAL B 2 16  ? -11.05100 -4.11436  -34.78950 1.000 620.63746 ? 16  VAL b C   1 
ATOM 376  O O   . VAL B 2 16  ? -11.08300 -4.91836  -35.72950 1.000 620.63746 ? 16  VAL b O   1 
ATOM 377  C CB  . VAL B 2 16  ? -8.97000  -4.07936  -33.32550 1.000 620.63746 ? 16  VAL b CB  1 
ATOM 378  C CG1 . VAL B 2 16  ? -8.81200  -2.56336  -33.17950 1.000 620.63746 ? 16  VAL b CG1 1 
ATOM 379  C CG2 . VAL B 2 16  ? -8.28000  -4.78736  -32.16350 1.000 620.63746 ? 16  VAL b CG2 1 
ATOM 380  N N   . LEU B 2 17  ? -11.58900 -2.89636  -34.86750 1.000 612.24976 ? 17  LEU b N   1 
ATOM 381  C CA  . LEU B 2 17  ? -11.90000 -2.23736  -36.12950 1.000 612.24976 ? 17  LEU b CA  1 
ATOM 382  C C   . LEU B 2 17  ? -11.10200 -0.94136  -36.25250 1.000 612.24976 ? 17  LEU b C   1 
ATOM 383  O O   . LEU B 2 17  ? -10.67100 -0.36236  -35.25050 1.000 612.24976 ? 17  LEU b O   1 
ATOM 384  C CB  . LEU B 2 17  ? -13.39600 -1.93536  -36.26150 1.000 612.24976 ? 17  LEU b CB  1 
ATOM 385  C CG  . LEU B 2 17  ? -14.26200 -2.97036  -36.98550 1.000 612.24976 ? 17  LEU b CG  1 
ATOM 386  C CD1 . LEU B 2 17  ? -13.78000 -3.17936  -38.40850 1.000 612.24976 ? 17  LEU b CD1 1 
ATOM 387  C CD2 . LEU B 2 17  ? -14.31700 -4.28336  -36.24450 1.000 612.24976 ? 17  LEU b CD2 1 
ATOM 388  N N   . ASP B 2 18  ? -10.89900 -0.49636  -37.49250 1.000 740.50512 ? 18  ASP b N   1 
ATOM 389  C CA  . ASP B 2 18  ? -10.15200 0.71964   -37.80650 1.000 740.50512 ? 18  ASP b CA  1 
ATOM 390  C C   . ASP B 2 18  ? -11.11400 1.81564   -38.24150 1.000 740.50512 ? 18  ASP b C   1 
ATOM 391  O O   . ASP B 2 18  ? -12.16400 1.53064   -38.82750 1.000 740.50512 ? 18  ASP b O   1 
ATOM 392  C CB  . ASP B 2 18  ? -9.11900  0.44764   -38.90750 1.000 740.50512 ? 18  ASP b CB  1 
ATOM 393  C CG  . ASP B 2 18  ? -8.05200  1.53264   -39.03550 1.000 740.50512 ? 18  ASP b CG  1 
ATOM 394  O OD1 . ASP B 2 18  ? -8.38400  2.72564   -39.19550 1.000 740.50512 ? 18  ASP b OD1 1 
ATOM 395  O OD2 . ASP B 2 18  ? -6.85800  1.17364   -39.03650 1.000 740.50512 ? 18  ASP b OD2 1 
ATOM 396  N N   . ALA B 2 19  ? -10.74200 3.07064   -37.96150 1.000 804.35095 ? 19  ALA b N   1 
ATOM 397  C CA  . ALA B 2 19  ? -11.55200 4.20064   -38.40650 1.000 804.35095 ? 19  ALA b CA  1 
ATOM 398  C C   . ALA B 2 19  ? -11.38600 4.45964   -39.89450 1.000 804.35095 ? 19  ALA b C   1 
ATOM 399  O O   . ALA B 2 19  ? -12.37400 4.71064   -40.59150 1.000 804.35095 ? 19  ALA b O   1 
ATOM 400  C CB  . ALA B 2 19  ? -11.19900 5.46464   -37.62250 1.000 804.35095 ? 19  ALA b CB  1 
ATOM 401  N N   . VAL B 2 20  ? -10.15800 4.41764   -40.39750 1.000 814.19162 ? 20  VAL b N   1 
ATOM 402  C CA  . VAL B 2 20  ? -9.92900  4.72664   -41.80350 1.000 814.19162 ? 20  VAL b CA  1 
ATOM 403  C C   . VAL B 2 20  ? -9.64800  3.47364   -42.62250 1.000 814.19162 ? 20  VAL b C   1 
ATOM 404  O O   . VAL B 2 20  ? -9.71900  3.51064   -43.85250 1.000 814.19162 ? 20  VAL b O   1 
ATOM 405  C CB  . VAL B 2 20  ? -8.80100  5.76364   -41.93750 1.000 814.19162 ? 20  VAL b CB  1 
ATOM 406  C CG1 . VAL B 2 20  ? -9.28200  7.10564   -41.43050 1.000 814.19162 ? 20  VAL b CG1 1 
ATOM 407  C CG2 . VAL B 2 20  ? -7.59300  5.32064   -41.15750 1.000 814.19162 ? 20  VAL b CG2 1 
ATOM 408  N N   . ARG B 2 21  ? -9.31000  2.35264   -41.98750 1.000 772.38236 ? 21  ARG b N   1 
ATOM 409  C CA  . ARG B 2 21  ? -9.09300  1.12064   -42.73850 1.000 772.38236 ? 21  ARG b CA  1 
ATOM 410  C C   . ARG B 2 21  ? -10.23100 0.11664   -42.61050 1.000 772.38236 ? 21  ARG b C   1 
ATOM 411  O O   . ARG B 2 21  ? -10.36800 -0.74936  -43.48050 1.000 772.38236 ? 21  ARG b O   1 
ATOM 412  C CB  . ARG B 2 21  ? -7.78500  0.45264   -42.30850 1.000 772.38236 ? 21  ARG b CB  1 
ATOM 413  C CG  . ARG B 2 21  ? -6.56900  1.34564   -42.43650 1.000 772.38236 ? 21  ARG b CG  1 
ATOM 414  C CD  . ARG B 2 21  ? -5.34400  0.61364   -41.95450 1.000 772.38236 ? 21  ARG b CD  1 
ATOM 415  N NE  . ARG B 2 21  ? -5.61500  -0.04336  -40.68250 1.000 772.38236 ? 21  ARG b NE  1 
ATOM 416  C CZ  . ARG B 2 21  ? -5.10500  -1.21436  -40.32850 1.000 772.38236 ? 21  ARG b CZ  1 
ATOM 417  N NH1 . ARG B 2 21  ? -4.30000  -1.85736  -41.15850 1.000 772.38236 ? 21  ARG b NH1 1 
ATOM 418  N NH2 . ARG B 2 21  ? -5.40700  -1.74236  -39.15350 1.000 772.38236 ? 21  ARG b NH2 1 
ATOM 419  N N   . GLY B 2 22  ? -11.04300 0.20464   -41.55850 1.000 793.89720 ? 22  GLY b N   1 
ATOM 420  C CA  . GLY B 2 22  ? -12.11100 -0.75636  -41.34050 1.000 793.89720 ? 22  GLY b CA  1 
ATOM 421  C C   . GLY B 2 22  ? -11.63300 -2.16336  -41.06650 1.000 793.89720 ? 22  GLY b C   1 
ATOM 422  O O   . GLY B 2 22  ? -12.30600 -3.12636  -41.44550 1.000 793.89720 ? 22  GLY b O   1 
ATOM 423  N N   . SER B 2 23  ? -10.48600 -2.30836  -40.42650 1.000 764.05646 ? 23  SER b N   1 
ATOM 424  C CA  . SER B 2 23  ? -9.85900  -3.60836  -40.25250 1.000 764.05646 ? 23  SER b CA  1 
ATOM 425  C C   . SER B 2 23  ? -9.30800  -3.69036  -38.83650 1.000 764.05646 ? 23  SER b C   1 
ATOM 426  O O   . SER B 2 23  ? -9.29100  -2.67736  -38.13050 1.000 764.05646 ? 23  SER b O   1 
ATOM 427  C CB  . SER B 2 23  ? -8.75600  -3.79936  -41.29750 1.000 764.05646 ? 23  SER b CB  1 
ATOM 428  O OG  . SER B 2 23  ? -7.55400  -3.16736  -40.89350 1.000 764.05646 ? 23  SER b OG  1 
ATOM 429  N N   . PRO B 2 24  ? -8.88500  -4.86236  -38.36350 1.000 735.77727 ? 24  PRO b N   1 
ATOM 430  C CA  . PRO B 2 24  ? -8.11800  -4.90836  -37.11350 1.000 735.77727 ? 24  PRO b CA  1 
ATOM 431  C C   . PRO B 2 24  ? -6.78900  -4.17236  -37.22350 1.000 735.77727 ? 24  PRO b C   1 
ATOM 432  O O   . PRO B 2 24  ? -6.29000  -3.88236  -38.31350 1.000 735.77727 ? 24  PRO b O   1 
ATOM 433  C CB  . PRO B 2 24  ? -7.91500  -6.40736  -36.88150 1.000 735.77727 ? 24  PRO b CB  1 
ATOM 434  C CG  . PRO B 2 24  ? -9.12700  -7.01736  -37.47850 1.000 735.77727 ? 24  PRO b CG  1 
ATOM 435  C CD  . PRO B 2 24  ? -9.48100  -6.17436  -38.67750 1.000 735.77727 ? 24  PRO b CD  1 
ATOM 436  N N   . ALA B 2 25  ? -6.23000  -3.84936  -36.05950 1.000 638.55527 ? 25  ALA b N   1 
ATOM 437  C CA  . ALA B 2 25  ? -5.04500  -3.00136  -35.98750 1.000 638.55527 ? 25  ALA b CA  1 
ATOM 438  C C   . ALA B 2 25  ? -3.83100  -3.78036  -36.47150 1.000 638.55527 ? 25  ALA b C   1 
ATOM 439  O O   . ALA B 2 25  ? -3.17400  -4.47336  -35.69550 1.000 638.55527 ? 25  ALA b O   1 
ATOM 440  C CB  . ALA B 2 25  ? -4.85300  -2.49836  -34.56150 1.000 638.55527 ? 25  ALA b CB  1 
ATOM 441  N N   . ILE B 2 26  ? -3.51400  -3.64836  -37.74950 1.000 588.76512 ? 26  ILE b N   1 
ATOM 442  C CA  . ILE B 2 26  ? -2.51400  -4.48536  -38.39550 1.000 588.76512 ? 26  ILE b CA  1 
ATOM 443  C C   . ILE B 2 26  ? -1.14100  -3.89736  -38.11250 1.000 588.76512 ? 26  ILE b C   1 
ATOM 444  O O   . ILE B 2 26  ? -0.82300  -2.80036  -38.59050 1.000 588.76512 ? 26  ILE b O   1 
ATOM 445  C CB  . ILE B 2 26  ? -2.77700  -4.59936  -39.90550 1.000 588.76512 ? 26  ILE b CB  1 
ATOM 446  C CG1 . ILE B 2 26  ? -4.07800  -5.36036  -40.16150 1.000 588.76512 ? 26  ILE b CG1 1 
ATOM 447  C CG2 . ILE B 2 26  ? -1.62200  -5.27836  -40.60450 1.000 588.76512 ? 26  ILE b CG2 1 
ATOM 448  C CD1 . ILE B 2 26  ? -4.58800  -5.25636  -41.58150 1.000 588.76512 ? 26  ILE b CD1 1 
ATOM 449  N N   . ASN B 2 27  ? -0.35300  -4.62236  -37.30050 1.000 526.57328 ? 27  ASN b N   1 
ATOM 450  C CA  . ASN B 2 27  ? 1.07600   -4.36736  -37.07350 1.000 526.57328 ? 27  ASN b CA  1 
ATOM 451  C C   . ASN B 2 27  ? 1.33900   -2.96536  -36.53150 1.000 526.57328 ? 27  ASN b C   1 
ATOM 452  O O   . ASN B 2 27  ? 2.13900   -2.20436  -37.08050 1.000 526.57328 ? 27  ASN b O   1 
ATOM 453  C CB  . ASN B 2 27  ? 1.89100   -4.61036  -38.34350 1.000 526.57328 ? 27  ASN b CB  1 
ATOM 454  C CG  . ASN B 2 27  ? 3.32000   -5.01336  -38.04450 1.000 526.57328 ? 27  ASN b CG  1 
ATOM 455  O OD1 . ASN B 2 27  ? 3.66800   -5.29536  -36.90350 1.000 526.57328 ? 27  ASN b OD1 1 
ATOM 456  N ND2 . ASN B 2 27  ? 4.16200   -5.01636  -39.06750 1.000 526.57328 ? 27  ASN b ND2 1 
ATOM 457  N N   . VAL B 2 28  ? 0.64700   -2.61736  -35.45350 1.000 504.58628 ? 28  VAL b N   1 
ATOM 458  C CA  . VAL B 2 28  ? 0.74000   -1.25536  -34.95350 1.000 504.58628 ? 28  VAL b CA  1 
ATOM 459  C C   . VAL B 2 28  ? 2.05100   -1.08236  -34.20950 1.000 504.58628 ? 28  VAL b C   1 
ATOM 460  O O   . VAL B 2 28  ? 2.31300   -1.76136  -33.21050 1.000 504.58628 ? 28  VAL b O   1 
ATOM 461  C CB  . VAL B 2 28  ? -0.46100  -0.90236  -34.07450 1.000 504.58628 ? 28  VAL b CB  1 
ATOM 462  C CG1 . VAL B 2 28  ? -0.16700  0.34864   -33.25850 1.000 504.58628 ? 28  VAL b CG1 1 
ATOM 463  C CG2 . VAL B 2 28  ? -1.65000  -0.68036  -34.95650 1.000 504.58628 ? 28  VAL b CG2 1 
ATOM 464  N N   . ALA B 2 29  ? 2.89500   -0.19136  -34.71450 1.000 490.63303 ? 29  ALA b N   1 
ATOM 465  C CA  . ALA B 2 29  ? 4.07800   0.20464   -33.97350 1.000 490.63303 ? 29  ALA b CA  1 
ATOM 466  C C   . ALA B 2 29  ? 3.65300   1.02064   -32.75950 1.000 490.63303 ? 29  ALA b C   1 
ATOM 467  O O   . ALA B 2 29  ? 2.92100   2.00764   -32.88650 1.000 490.63303 ? 29  ALA b O   1 
ATOM 468  C CB  . ALA B 2 29  ? 5.02600   0.99064   -34.87350 1.000 490.63303 ? 29  ALA b CB  1 
ATOM 469  N N   . VAL B 2 30  ? 4.13200   0.61764   -31.58550 1.000 444.47378 ? 30  VAL b N   1 
ATOM 470  C CA  . VAL B 2 30  ? 3.53000   0.97264   -30.30550 1.000 444.47378 ? 30  VAL b CA  1 
ATOM 471  C C   . VAL B 2 30  ? 4.45700   1.91964   -29.55750 1.000 444.47378 ? 30  VAL b C   1 
ATOM 472  O O   . VAL B 2 30  ? 5.65000   1.63764   -29.40950 1.000 444.47378 ? 30  VAL b O   1 
ATOM 473  C CB  . VAL B 2 30  ? 3.24600   -0.29236  -29.47150 1.000 444.47378 ? 30  VAL b CB  1 
ATOM 474  C CG1 . VAL B 2 30  ? 3.03400   0.02364   -27.99550 1.000 444.47378 ? 30  VAL b CG1 1 
ATOM 475  C CG2 . VAL B 2 30  ? 2.05100   -1.01236  -30.02250 1.000 444.47378 ? 30  VAL b CG2 1 
ATOM 476  N N   . HIS B 2 31  ? 3.91200   3.04364   -29.09950 1.000 385.68240 ? 31  HIS b N   1 
ATOM 477  C CA  . HIS B 2 31  ? 4.55500   3.88764   -28.10150 1.000 385.68240 ? 31  HIS b CA  1 
ATOM 478  C C   . HIS B 2 31  ? 3.64800   3.96964   -26.88250 1.000 385.68240 ? 31  HIS b C   1 
ATOM 479  O O   . HIS B 2 31  ? 2.50800   4.43664   -26.98050 1.000 385.68240 ? 31  HIS b O   1 
ATOM 480  C CB  . HIS B 2 31  ? 4.84700   5.28264   -28.65550 1.000 385.68240 ? 31  HIS b CB  1 
ATOM 481  C CG  . HIS B 2 31  ? 6.24200   5.44964   -29.17750 1.000 385.68240 ? 31  HIS b CG  1 
ATOM 482  N ND1 . HIS B 2 31  ? 7.22100   6.12764   -28.48350 1.000 385.68240 ? 31  HIS b ND1 1 
ATOM 483  C CD2 . HIS B 2 31  ? 6.82700   5.00964   -30.31650 1.000 385.68240 ? 31  HIS b CD2 1 
ATOM 484  C CE1 . HIS B 2 31  ? 8.34400   6.11164   -29.18050 1.000 385.68240 ? 31  HIS b CE1 1 
ATOM 485  N NE2 . HIS B 2 31  ? 8.13100   5.43864   -30.29650 1.000 385.68240 ? 31  HIS b NE2 1 
ATOM 486  N N   . VAL B 2 32  ? 4.15400   3.51364   -25.74450 1.000 435.02240 ? 32  VAL b N   1 
ATOM 487  C CA  . VAL B 2 32  ? 3.37300   3.40564   -24.51750 1.000 435.02240 ? 32  VAL b CA  1 
ATOM 488  C C   . VAL B 2 32  ? 3.47700   4.71564   -23.75050 1.000 435.02240 ? 32  VAL b C   1 
ATOM 489  O O   . VAL B 2 32  ? 4.57700   5.21464   -23.49750 1.000 435.02240 ? 32  VAL b O   1 
ATOM 490  C CB  . VAL B 2 32  ? 3.86500   2.21664   -23.67150 1.000 435.02240 ? 32  VAL b CB  1 
ATOM 491  C CG1 . VAL B 2 32  ? 3.23200   2.22864   -22.28650 1.000 435.02240 ? 32  VAL b CG1 1 
ATOM 492  C CG2 . VAL B 2 32  ? 3.60700   0.90264   -24.39550 1.000 435.02240 ? 32  VAL b CG2 1 
ATOM 493  N N   . PHE B 2 33  ? 2.33200   5.27564   -23.37250 1.000 397.03580 ? 33  PHE b N   1 
ATOM 494  C CA  . PHE B 2 33  ? 2.29400   6.56264   -22.69950 1.000 397.03580 ? 33  PHE b CA  1 
ATOM 495  C C   . PHE B 2 33  ? 1.67700   6.40764   -21.31350 1.000 397.03580 ? 33  PHE b C   1 
ATOM 496  O O   . PHE B 2 33  ? 0.84800   5.52564   -21.07450 1.000 397.03580 ? 33  PHE b O   1 
ATOM 497  C CB  . PHE B 2 33  ? 1.53400   7.59464   -23.54150 1.000 397.03580 ? 33  PHE b CB  1 
ATOM 498  C CG  . PHE B 2 33  ? 2.35200   8.18164   -24.66150 1.000 397.03580 ? 33  PHE b CG  1 
ATOM 499  C CD1 . PHE B 2 33  ? 2.54300   7.48264   -25.84350 1.000 397.03580 ? 33  PHE b CD1 1 
ATOM 500  C CD2 . PHE B 2 33  ? 2.93600   9.42864   -24.53050 1.000 397.03580 ? 33  PHE b CD2 1 
ATOM 501  C CE1 . PHE B 2 33  ? 3.30100   8.01764   -26.86950 1.000 397.03580 ? 33  PHE b CE1 1 
ATOM 502  C CE2 . PHE B 2 33  ? 3.68800   9.97164   -25.55350 1.000 397.03580 ? 33  PHE b CE2 1 
ATOM 503  C CZ  . PHE B 2 33  ? 3.86700   9.26264   -26.72450 1.000 397.03580 ? 33  PHE b CZ  1 
ATOM 504  N N   . ARG B 2 34  ? 2.09400   7.28464   -20.39850 1.000 439.19523 ? 34  ARG b N   1 
ATOM 505  C CA  . ARG B 2 34  ? 1.76200   7.17464   -18.98250 1.000 439.19523 ? 34  ARG b CA  1 
ATOM 506  C C   . ARG B 2 34  ? 1.11500   8.46064   -18.49250 1.000 439.19523 ? 34  ARG b C   1 
ATOM 507  O O   . ARG B 2 34  ? 1.70900   9.53564   -18.59950 1.000 439.19523 ? 34  ARG b O   1 
ATOM 508  C CB  . ARG B 2 34  ? 3.01100   6.86964   -18.14250 1.000 439.19523 ? 34  ARG b CB  1 
ATOM 509  C CG  . ARG B 2 34  ? 2.81000   7.08664   -16.65350 1.000 439.19523 ? 34  ARG b CG  1 
ATOM 510  C CD  . ARG B 2 34  ? 4.09100   6.94464   -15.85750 1.000 439.19523 ? 34  ARG b CD  1 
ATOM 511  N NE  . ARG B 2 34  ? 3.81800   7.04964   -14.42850 1.000 439.19523 ? 34  ARG b NE  1 
ATOM 512  C CZ  . ARG B 2 34  ? 3.77400   8.19764   -13.76250 1.000 439.19523 ? 34  ARG b CZ  1 
ATOM 513  N NH1 . ARG B 2 34  ? 3.98700   9.34164   -14.39550 1.000 439.19523 ? 34  ARG b NH1 1 
ATOM 514  N NH2 . ARG B 2 34  ? 3.51400   8.20164   -12.46450 1.000 439.19523 ? 34  ARG b NH2 1 
ATOM 515  N N   . LYS B 2 35  ? -0.08400  8.33964   -17.92750 1.000 431.89961 ? 35  LYS b N   1 
ATOM 516  C CA  . LYS B 2 35  ? -0.84300  9.49164   -17.45250 1.000 431.89961 ? 35  LYS b CA  1 
ATOM 517  C C   . LYS B 2 35  ? -0.20800  10.05664  -16.18550 1.000 431.89961 ? 35  LYS b C   1 
ATOM 518  O O   . LYS B 2 35  ? 0.04700   9.31664   -15.22850 1.000 431.89961 ? 35  LYS b O   1 
ATOM 519  C CB  . LYS B 2 35  ? -2.29100  9.08464   -17.19650 1.000 431.89961 ? 35  LYS b CB  1 
ATOM 520  C CG  . LYS B 2 35  ? -3.19600  10.18764  -16.66850 1.000 431.89961 ? 35  LYS b CG  1 
ATOM 521  C CD  . LYS B 2 35  ? -3.44700  11.25964  -17.71350 1.000 431.89961 ? 35  LYS b CD  1 
ATOM 522  C CE  . LYS B 2 35  ? -4.56400  12.18964  -17.27950 1.000 431.89961 ? 35  LYS b CE  1 
ATOM 523  N NZ  . LYS B 2 35  ? -5.87300  11.47664  -17.24850 1.000 431.89961 ? 35  LYS b NZ  1 
ATOM 524  N N   . ALA B 2 36  ? 0.05500   11.36164  -16.18250 1.000 433.61817 ? 36  ALA b N   1 
ATOM 525  C CA  . ALA B 2 36  ? 0.58400   12.04464  -15.01350 1.000 433.61817 ? 36  ALA b CA  1 
ATOM 526  C C   . ALA B 2 36  ? -0.51700  12.88864  -14.36950 1.000 433.61817 ? 36  ALA b C   1 
ATOM 527  O O   . ALA B 2 36  ? -1.66900  12.88964  -14.81050 1.000 433.61817 ? 36  ALA b O   1 
ATOM 528  C CB  . ALA B 2 36  ? 1.80000   12.88564  -15.39550 1.000 433.61817 ? 36  ALA b CB  1 
ATOM 529  N N   . ALA B 2 37  ? -0.16600  13.62964  -13.31550 1.000 401.47043 ? 37  ALA b N   1 
ATOM 530  C CA  . ALA B 2 37  ? -1.15500  14.43364  -12.60850 1.000 401.47043 ? 37  ALA b CA  1 
ATOM 531  C C   . ALA B 2 37  ? -1.46600  15.73564  -13.33050 1.000 401.47043 ? 37  ALA b C   1 
ATOM 532  O O   . ALA B 2 37  ? -2.56700  16.27264  -13.16950 1.000 401.47043 ? 37  ALA b O   1 
ATOM 533  C CB  . ALA B 2 37  ? -0.67600  14.73064  -11.18750 1.000 401.47043 ? 37  ALA b CB  1 
ATOM 534  N N   . ASP B 2 38  ? -0.53700  16.24064  -14.13550 1.000 393.27881 ? 38  ASP b N   1 
ATOM 535  C CA  . ASP B 2 38  ? -0.75500  17.42764  -14.95150 1.000 393.27881 ? 38  ASP b CA  1 
ATOM 536  C C   . ASP B 2 38  ? -1.16400  17.03964  -16.36950 1.000 393.27881 ? 38  ASP b C   1 
ATOM 537  O O   . ASP B 2 38  ? -0.90000  17.76264  -17.33250 1.000 393.27881 ? 38  ASP b O   1 
ATOM 538  C CB  . ASP B 2 38  ? 0.49100   18.30564  -14.96250 1.000 393.27881 ? 38  ASP b CB  1 
ATOM 539  C CG  . ASP B 2 38  ? 1.75000   17.52064  -15.26450 1.000 393.27881 ? 38  ASP b CG  1 
ATOM 540  O OD1 . ASP B 2 38  ? 1.68000   16.27464  -15.32350 1.000 393.27881 ? 38  ASP b OD1 1 
ATOM 541  O OD2 . ASP B 2 38  ? 2.81200   18.15164  -15.44350 1.000 393.27881 ? 38  ASP b OD2 1 
ATOM 542  N N   . ASP B 2 39  ? -1.75900  15.84964  -16.48850 1.000 460.82740 ? 39  ASP b N   1 
ATOM 543  C CA  . ASP B 2 39  ? -2.52200  15.30964  -17.61450 1.000 460.82740 ? 39  ASP b CA  1 
ATOM 544  C C   . ASP B 2 39  ? -1.67800  14.89564  -18.81450 1.000 460.82740 ? 39  ASP b C   1 
ATOM 545  O O   . ASP B 2 39  ? -2.20100  14.22564  -19.71050 1.000 460.82740 ? 39  ASP b O   1 
ATOM 546  C CB  . ASP B 2 39  ? -3.60300  16.28664  -18.09250 1.000 460.82740 ? 39  ASP b CB  1 
ATOM 547  C CG  . ASP B 2 39  ? -4.59800  16.62264  -17.00650 1.000 460.82740 ? 39  ASP b CG  1 
ATOM 548  O OD1 . ASP B 2 39  ? -5.07000  15.69164  -16.32250 1.000 460.82740 ? 39  ASP b OD1 1 
ATOM 549  O OD2 . ASP B 2 39  ? -4.89700  17.82164  -16.82850 1.000 460.82740 ? 39  ASP b OD2 1 
ATOM 550  N N   . THR B 2 40  ? -0.38800  15.20464  -18.83850 1.000 508.12429 ? 40  THR b N   1 
ATOM 551  C CA  . THR B 2 40  ? 0.45100   14.92464  -19.99350 1.000 508.12429 ? 40  THR b CA  1 
ATOM 552  C C   . THR B 2 40  ? 1.09200   13.54964  -19.86050 1.000 508.12429 ? 40  THR b C   1 
ATOM 553  O O   . THR B 2 40  ? 1.17900   12.98864  -18.76550 1.000 508.12429 ? 40  THR b O   1 
ATOM 554  C CB  . THR B 2 40  ? 1.49700   16.03964  -20.18250 1.000 508.12429 ? 40  THR b CB  1 
ATOM 555  O OG1 . THR B 2 40  ? 1.39600   16.56664  -21.51350 1.000 508.12429 ? 40  THR b OG1 1 
ATOM 556  C CG2 . THR B 2 40  ? 2.96500   15.63364  -19.82650 1.000 508.12429 ? 40  THR b CG2 1 
ATOM 557  N N   . TRP B 2 41  ? 1.49600   12.99064  -20.99750 1.000 532.01343 ? 41  TRP b N   1 
ATOM 558  C CA  . TRP B 2 41  ? 1.95400   11.61464  -21.07550 1.000 532.01343 ? 41  TRP b CA  1 
ATOM 559  C C   . TRP B 2 41  ? 3.31700   11.59964  -21.75350 1.000 532.01343 ? 41  TRP b C   1 
ATOM 560  O O   . TRP B 2 41  ? 3.60400   12.45364  -22.59850 1.000 532.01343 ? 41  TRP b O   1 
ATOM 561  C CB  . TRP B 2 41  ? 0.97800   10.73564  -21.85650 1.000 532.01343 ? 41  TRP b CB  1 
ATOM 562  C CG  . TRP B 2 41  ? -0.50500  10.85464  -21.58450 1.000 532.01343 ? 41  TRP b CG  1 
ATOM 563  C CD1 . TRP B 2 41  ? -1.28800  11.97464  -21.66650 1.000 532.01343 ? 41  TRP b CD1 1 
ATOM 564  C CD2 . TRP B 2 41  ? -1.39300  9.77764   -21.28750 1.000 532.01343 ? 41  TRP b CD2 1 
ATOM 565  N NE1 . TRP B 2 41  ? -2.59200  11.66764  -21.38450 1.000 532.01343 ? 41  TRP b NE1 1 
ATOM 566  C CE2 . TRP B 2 41  ? -2.68500  10.32264  -21.15250 1.000 532.01343 ? 41  TRP b CE2 1 
ATOM 567  C CE3 . TRP B 2 41  ? -1.21700  8.40464   -21.09750 1.000 532.01343 ? 41  TRP b CE3 1 
ATOM 568  C CZ2 . TRP B 2 41  ? -3.79200  9.54464   -20.84050 1.000 532.01343 ? 41  TRP b CZ2 1 
ATOM 569  C CZ3 . TRP B 2 41  ? -2.31800  7.63364   -20.78350 1.000 532.01343 ? 41  TRP b CZ3 1 
ATOM 570  C CH2 . TRP B 2 41  ? -3.58900  8.20664   -20.65750 1.000 532.01343 ? 41  TRP b CH2 1 
ATOM 571  N N   . GLU B 2 42  ? 4.15000   10.63364  -21.38350 1.000 449.58168 ? 42  GLU b N   1 
ATOM 572  C CA  . GLU B 2 42  ? 5.50900   10.45864  -21.87850 1.000 449.58168 ? 42  GLU b CA  1 
ATOM 573  C C   . GLU B 2 42  ? 5.67800   9.08364   -22.51450 1.000 449.58168 ? 42  GLU b C   1 
ATOM 574  O O   . GLU B 2 42  ? 5.07900   8.11264   -22.04550 1.000 449.58168 ? 42  GLU b O   1 
ATOM 575  C CB  . GLU B 2 42  ? 6.51000   10.61664  -20.73450 1.000 449.58168 ? 42  GLU b CB  1 
ATOM 576  C CG  . GLU B 2 42  ? 6.77300   12.05764  -20.33750 1.000 449.58168 ? 42  GLU b CG  1 
ATOM 577  C CD  . GLU B 2 42  ? 8.02700   12.21464  -19.49950 1.000 449.58168 ? 42  GLU b CD  1 
ATOM 578  O OE1 . GLU B 2 42  ? 8.64800   11.18864  -19.15550 1.000 449.58168 ? 42  GLU b OE1 1 
ATOM 579  O OE2 . GLU B 2 42  ? 8.39100   13.36564  -19.18250 1.000 449.58168 ? 42  GLU b OE2 1 
ATOM 580  N N   . PRO B 2 43  ? 6.48500   8.95664   -23.57150 1.000 461.68714 ? 43  PRO b N   1 
ATOM 581  C CA  . PRO B 2 43  ? 6.66400   7.64364   -24.21150 1.000 461.68714 ? 43  PRO b CA  1 
ATOM 582  C C   . PRO B 2 43  ? 7.48100   6.68764   -23.34850 1.000 461.68714 ? 43  PRO b C   1 
ATOM 583  O O   . PRO B 2 43  ? 8.26300   7.11064   -22.49450 1.000 461.68714 ? 43  PRO b O   1 
ATOM 584  C CB  . PRO B 2 43  ? 7.40200   7.97664   -25.51550 1.000 461.68714 ? 43  PRO b CB  1 
ATOM 585  C CG  . PRO B 2 43  ? 7.28000   9.45764   -25.68350 1.000 461.68714 ? 43  PRO b CG  1 
ATOM 586  C CD  . PRO B 2 43  ? 7.16900   10.02764  -24.31250 1.000 461.68714 ? 43  PRO b CD  1 
ATOM 587  N N   . PHE B 2 44  ? 7.28400   5.38364   -23.57550 1.000 482.87144 ? 44  PHE b N   1 
ATOM 588  C CA  . PHE B 2 44  ? 7.98900   4.33964   -22.82650 1.000 482.87144 ? 44  PHE b CA  1 
ATOM 589  C C   . PHE B 2 44  ? 8.89500   3.48964   -23.68750 1.000 482.87144 ? 44  PHE b C   1 
ATOM 590  O O   . PHE B 2 44  ? 10.10200  3.41264   -23.41750 1.000 482.87144 ? 44  PHE b O   1 
ATOM 591  C CB  . PHE B 2 44  ? 6.96200   3.46864   -22.07350 1.000 482.87144 ? 44  PHE b CB  1 
ATOM 592  C CG  . PHE B 2 44  ? 7.49800   2.13164   -21.62750 1.000 482.87144 ? 44  PHE b CG  1 
ATOM 593  C CD1 . PHE B 2 44  ? 8.52800   2.03964   -20.69650 1.000 482.87144 ? 44  PHE b CD1 1 
ATOM 594  C CD2 . PHE B 2 44  ? 6.95200   0.96264   -22.13150 1.000 482.87144 ? 44  PHE b CD2 1 
ATOM 595  C CE1 . PHE B 2 44  ? 9.01200   0.80564   -20.29750 1.000 482.87144 ? 44  PHE b CE1 1 
ATOM 596  C CE2 . PHE B 2 44  ? 7.43000   -0.27336  -21.73750 1.000 482.87144 ? 44  PHE b CE2 1 
ATOM 597  C CZ  . PHE B 2 44  ? 8.46000   -0.35136  -20.81850 1.000 482.87144 ? 44  PHE b CZ  1 
ATOM 598  N N   . ALA B 2 45  ? 8.38400   2.83164   -24.73450 1.000 540.06642 ? 45  ALA b N   1 
ATOM 599  C CA  . ALA B 2 45  ? 9.18900   1.88764   -25.51050 1.000 540.06642 ? 45  ALA b CA  1 
ATOM 600  C C   . ALA B 2 45  ? 8.59400   1.74264   -26.90850 1.000 540.06642 ? 45  ALA b C   1 
ATOM 601  O O   . ALA B 2 45  ? 7.72100   2.51564   -27.31650 1.000 540.06642 ? 45  ALA b O   1 
ATOM 602  C CB  . ALA B 2 45  ? 9.29400   0.53164   -24.79750 1.000 540.06642 ? 45  ALA b CB  1 
ATOM 603  N N   . SER B 2 46  ? 9.07200   0.73864   -27.64550 1.000 521.60383 ? 46  SER b N   1 
ATOM 604  C CA  . SER B 2 46  ? 8.70900   0.57164   -29.04550 1.000 521.60383 ? 46  SER b CA  1 
ATOM 605  C C   . SER B 2 46  ? 8.44000   -0.89936  -29.33450 1.000 521.60383 ? 46  SER b C   1 
ATOM 606  O O   . SER B 2 46  ? 8.92600   -1.79236  -28.63650 1.000 521.60383 ? 46  SER b O   1 
ATOM 607  C CB  . SER B 2 46  ? 9.80100   1.11364   -29.97850 1.000 521.60383 ? 46  SER b CB  1 
ATOM 608  O OG  . SER B 2 46  ? 10.12600  2.45564   -29.66050 1.000 521.60383 ? 46  SER b OG  1 
ATOM 609  N N   . GLY B 2 47  ? 7.66500   -1.13236  -30.38750 1.000 469.76728 ? 47  GLY b N   1 
ATOM 610  C CA  . GLY B 2 47  ? 7.25800   -2.47436  -30.75650 1.000 469.76728 ? 47  GLY b CA  1 
ATOM 611  C C   . GLY B 2 47  ? 6.52600   -2.44336  -32.07950 1.000 469.76728 ? 47  GLY b C   1 
ATOM 612  O O   . GLY B 2 47  ? 6.62700   -1.47336  -32.83350 1.000 469.76728 ? 47  GLY b O   1 
ATOM 613  N N   . LYS B 2 48  ? 5.81100   -3.53436  -32.36450 1.000 440.72413 ? 48  LYS b N   1 
ATOM 614  C CA  . LYS B 2 48  ? 4.91900   -3.64136  -33.51550 1.000 440.72413 ? 48  LYS b CA  1 
ATOM 615  C C   . LYS B 2 48  ? 3.92800   -4.77236  -33.27050 1.000 440.72413 ? 48  LYS b C   1 
ATOM 616  O O   . LYS B 2 48  ? 4.34600   -5.91336  -33.05150 1.000 440.72413 ? 48  LYS b O   1 
ATOM 617  C CB  . LYS B 2 48  ? 5.70700   -3.88436  -34.80650 1.000 440.72413 ? 48  LYS b CB  1 
ATOM 618  C CG  . LYS B 2 48  ? 5.72100   -2.68836  -35.73450 1.000 440.72413 ? 48  LYS b CG  1 
ATOM 619  C CD  . LYS B 2 48  ? 6.45700   -2.98336  -37.02050 1.000 440.72413 ? 48  LYS b CD  1 
ATOM 620  C CE  . LYS B 2 48  ? 6.50800   -1.74736  -37.89850 1.000 440.72413 ? 48  LYS b CE  1 
ATOM 621  N NZ  . LYS B 2 48  ? 7.27100   -1.99236  -39.15050 1.000 440.72413 ? 48  LYS b NZ  1 
ATOM 622  N N   . THR B 2 49  ? 2.62600   -4.47036  -33.34350 1.000 518.12379 ? 49  THR b N   1 
ATOM 623  C CA  . THR B 2 49  ? 1.60500   -5.43436  -32.94150 1.000 518.12379 ? 49  THR b CA  1 
ATOM 624  C C   . THR B 2 49  ? 1.42800   -6.54736  -33.96950 1.000 518.12379 ? 49  THR b C   1 
ATOM 625  O O   . THR B 2 49  ? 2.17700   -6.68936  -34.93550 1.000 518.12379 ? 49  THR b O   1 
ATOM 626  C CB  . THR B 2 49  ? 0.22900   -4.78836  -32.76050 1.000 518.12379 ? 49  THR b CB  1 
ATOM 627  O OG1 . THR B 2 49  ? -0.23400  -4.26236  -34.00950 1.000 518.12379 ? 49  THR b OG1 1 
ATOM 628  C CG2 . THR B 2 49  ? 0.21300   -3.72436  -31.69050 1.000 518.12379 ? 49  THR b CG2 1 
ATOM 629  N N   . SER B 2 50  ? 0.39400   -7.34336  -33.73650 1.000 571.58181 ? 50  SER b N   1 
ATOM 630  C CA  . SER B 2 50  ? -0.04300  -8.36136  -34.67750 1.000 571.58181 ? 50  SER b CA  1 
ATOM 631  C C   . SER B 2 50  ? -1.00000  -7.73036  -35.68450 1.000 571.58181 ? 50  SER b C   1 
ATOM 632  O O   . SER B 2 50  ? -1.17200  -6.50936  -35.74050 1.000 571.58181 ? 50  SER b O   1 
ATOM 633  C CB  . SER B 2 50  ? -0.69700  -9.51736  -33.93050 1.000 571.58181 ? 50  SER b CB  1 
ATOM 634  O OG  . SER B 2 50  ? -1.94500  -9.11436  -33.39350 1.000 571.58181 ? 50  SER b OG  1 
ATOM 635  N N   . GLU B 2 51  ? -1.63900  -8.57636  -36.49650 1.000 582.75924 ? 51  GLU b N   1 
ATOM 636  C CA  . GLU B 2 51  ? -2.69700  -8.10236  -37.37950 1.000 582.75924 ? 51  GLU b CA  1 
ATOM 637  C C   . GLU B 2 51  ? -3.92400  -7.67136  -36.58950 1.000 582.75924 ? 51  GLU b C   1 
ATOM 638  O O   . GLU B 2 51  ? -4.62800  -6.73936  -36.99550 1.000 582.75924 ? 51  GLU b O   1 
ATOM 639  C CB  . GLU B 2 51  ? -3.07100  -9.19736  -38.37650 1.000 582.75924 ? 51  GLU b CB  1 
ATOM 640  C CG  . GLU B 2 51  ? -1.88900  -9.77536  -39.13350 1.000 582.75924 ? 51  GLU b CG  1 
ATOM 641  C CD  . GLU B 2 51  ? -1.22900  -8.76236  -40.03650 1.000 582.75924 ? 51  GLU b CD  1 
ATOM 642  O OE1 . GLU B 2 51  ? -0.18800  -8.20236  -39.63750 1.000 582.75924 ? 51  GLU b OE1 1 
ATOM 643  O OE2 . GLU B 2 51  ? -1.74400  -8.53636  -41.15150 1.000 582.75924 ? 51  GLU b OE2 1 
ATOM 644  N N   . SER B 2 52  ? -4.18800  -8.33136  -35.46250 1.000 524.86082 ? 52  SER b N   1 
ATOM 645  C CA  . SER B 2 52  ? -5.32400  -8.02536  -34.60450 1.000 524.86082 ? 52  SER b CA  1 
ATOM 646  C C   . SER B 2 52  ? -4.97800  -7.03436  -33.50250 1.000 524.86082 ? 52  SER b C   1 
ATOM 647  O O   . SER B 2 52  ? -5.73600  -6.91036  -32.53650 1.000 524.86082 ? 52  SER b O   1 
ATOM 648  C CB  . SER B 2 52  ? -5.88400  -9.31436  -33.99350 1.000 524.86082 ? 52  SER b CB  1 
ATOM 649  O OG  . SER B 2 52  ? -6.18000  -9.15236  -32.61650 1.000 524.86082 ? 52  SER b OG  1 
ATOM 650  N N   . GLY B 2 53  ? -3.84800  -6.34236  -33.61450 1.000 543.15882 ? 53  GLY b N   1 
ATOM 651  C CA  . GLY B 2 53  ? -3.50800  -5.31236  -32.65550 1.000 543.15882 ? 53  GLY b CA  1 
ATOM 652  C C   . GLY B 2 53  ? -2.84100  -5.79136  -31.40050 1.000 543.15882 ? 53  GLY b C   1 
ATOM 653  O O   . GLY B 2 53  ? -2.81300  -5.05136  -30.41250 1.000 543.15882 ? 53  GLY b O   1 
ATOM 654  N N   . GLU B 2 54  ? -2.25900  -6.98236  -31.41650 1.000 567.79074 ? 54  GLU b N   1 
ATOM 655  C CA  . GLU B 2 54  ? -1.73100  -7.58336  -30.20650 1.000 567.79074 ? 54  GLU b CA  1 
ATOM 656  C C   . GLU B 2 54  ? -0.20700  -7.54136  -30.19850 1.000 567.79074 ? 54  GLU b C   1 
ATOM 657  O O   . GLU B 2 54  ? 0.45400   -8.02436  -31.12450 1.000 567.79074 ? 54  GLU b O   1 
ATOM 658  C CB  . GLU B 2 54  ? -2.26000  -9.00836  -30.05350 1.000 567.79074 ? 54  GLU b CB  1 
ATOM 659  C CG  . GLU B 2 54  ? -3.77500  -9.07636  -30.29550 1.000 567.79074 ? 54  GLU b CG  1 
ATOM 660  C CD  . GLU B 2 54  ? -4.36300  -10.45736 -30.07650 1.000 567.79074 ? 54  GLU b CD  1 
ATOM 661  O OE1 . GLU B 2 54  ? -3.58100  -11.39636 -29.83650 1.000 567.79074 ? 54  GLU b OE1 1 
ATOM 662  O OE2 . GLU B 2 54  ? -5.60200  -10.60236 -30.14850 1.000 567.79074 ? 54  GLU b OE2 1 
ATOM 663  N N   . LEU B 2 55  ? 0.33500   -6.94136  -29.13850 1.000 537.66347 ? 55  LEU b N   1 
ATOM 664  C CA  . LEU B 2 55  ? 1.77200   -6.83836  -28.90050 1.000 537.66347 ? 55  LEU b CA  1 
ATOM 665  C C   . LEU B 2 55  ? 2.04500   -7.22036  -27.45650 1.000 537.66347 ? 55  LEU b C   1 
ATOM 666  O O   . LEU B 2 55  ? 1.40600   -6.69636  -26.53750 1.000 537.66347 ? 55  LEU b O   1 
ATOM 667  C CB  . LEU B 2 55  ? 2.29500   -5.43136  -29.18350 1.000 537.66347 ? 55  LEU b CB  1 
ATOM 668  C CG  . LEU B 2 55  ? 3.73300   -5.17336  -28.73050 1.000 537.66347 ? 55  LEU b CG  1 
ATOM 669  C CD1 . LEU B 2 55  ? 4.73100   -5.40636  -29.83750 1.000 537.66347 ? 55  LEU b CD1 1 
ATOM 670  C CD2 . LEU B 2 55  ? 3.85700   -3.76136  -28.17250 1.000 537.66347 ? 55  LEU b CD2 1 
ATOM 671  N N   . HIS B 2 56  ? 2.98300   -8.13936  -27.26450 1.000 442.19814 ? 56  HIS b N   1 
ATOM 672  C CA  . HIS B 2 56  ? 3.28500   -8.69036  -25.95950 1.000 442.19814 ? 56  HIS b CA  1 
ATOM 673  C C   . HIS B 2 56  ? 4.79300   -8.80636  -25.81350 1.000 442.19814 ? 56  HIS b C   1 
ATOM 674  O O   . HIS B 2 56  ? 5.53600   -8.81636  -26.79850 1.000 442.19814 ? 56  HIS b O   1 
ATOM 675  C CB  . HIS B 2 56  ? 2.59700   -10.04636 -25.78150 1.000 442.19814 ? 56  HIS b CB  1 
ATOM 676  C CG  . HIS B 2 56  ? 1.11700   -9.93536  -25.60150 1.000 442.19814 ? 56  HIS b CG  1 
ATOM 677  N ND1 . HIS B 2 56  ? 0.21900   -10.40436 -26.53550 1.000 442.19814 ? 56  HIS b ND1 1 
ATOM 678  C CD2 . HIS B 2 56  ? 0.37900   -9.35536  -24.62750 1.000 442.19814 ? 56  HIS b CD2 1 
ATOM 679  C CE1 . HIS B 2 56  ? -1.01000  -10.14536 -26.12850 1.000 442.19814 ? 56  HIS b CE1 1 
ATOM 680  N NE2 . HIS B 2 56  ? -0.94100  -9.51136  -24.97150 1.000 442.19814 ? 56  HIS b NE2 1 
ATOM 681  N N   . GLY B 2 57  ? 5.24700   -8.89836  -24.56950 1.000 509.51027 ? 57  GLY b N   1 
ATOM 682  C CA  . GLY B 2 57  ? 6.65600   -9.11136  -24.32450 1.000 509.51027 ? 57  GLY b CA  1 
ATOM 683  C C   . GLY B 2 57  ? 7.54300   -7.91336  -24.55750 1.000 509.51027 ? 57  GLY b C   1 
ATOM 684  O O   . GLY B 2 57  ? 8.67000   -8.07936  -25.03450 1.000 509.51027 ? 57  GLY b O   1 
ATOM 685  N N   . LEU B 2 58  ? 7.05800   -6.70336  -24.26750 1.000 475.01327 ? 58  LEU b N   1 
ATOM 686  C CA  . LEU B 2 58  ? 7.95000   -5.54936  -24.25950 1.000 475.01327 ? 58  LEU b CA  1 
ATOM 687  C C   . LEU B 2 58  ? 8.98200   -5.67036  -23.15050 1.000 475.01327 ? 58  LEU b C   1 
ATOM 688  O O   . LEU B 2 58  ? 10.16500  -5.37936  -23.35950 1.000 475.01327 ? 58  LEU b O   1 
ATOM 689  C CB  . LEU B 2 58  ? 7.15600   -4.25636  -24.10550 1.000 475.01327 ? 58  LEU b CB  1 
ATOM 690  C CG  . LEU B 2 58  ? 6.32300   -3.85636  -25.31450 1.000 475.01327 ? 58  LEU b CG  1 
ATOM 691  C CD1 . LEU B 2 58  ? 5.58600   -2.56336  -25.02850 1.000 475.01327 ? 58  LEU b CD1 1 
ATOM 692  C CD2 . LEU B 2 58  ? 7.22400   -3.71236  -26.52250 1.000 475.01327 ? 58  LEU b CD2 1 
ATOM 693  N N   . THR B 2 59  ? 8.54700   -6.08736  -21.96450 1.000 551.64113 ? 59  THR b N   1 
ATOM 694  C CA  . THR B 2 59  ? 9.43400   -6.47736  -20.87550 1.000 551.64113 ? 59  THR b CA  1 
ATOM 695  C C   . THR B 2 59  ? 8.98100   -7.85436  -20.38750 1.000 551.64113 ? 59  THR b C   1 
ATOM 696  O O   . THR B 2 59  ? 8.08400   -8.47436  -20.96950 1.000 551.64113 ? 59  THR b O   1 
ATOM 697  C CB  . THR B 2 59  ? 9.44000   -5.42436  -19.75350 1.000 551.64113 ? 59  THR b CB  1 
ATOM 698  O OG1 . THR B 2 59  ? 8.10100   -5.18536  -19.30850 1.000 551.64113 ? 59  THR b OG1 1 
ATOM 699  C CG2 . THR B 2 59  ? 10.05800  -4.10536  -20.22250 1.000 551.64113 ? 59  THR b CG2 1 
ATOM 700  N N   . THR B 2 60  ? 9.62400   -8.34336  -19.32650 1.000 553.51260 ? 60  THR b N   1 
ATOM 701  C CA  . THR B 2 60  ? 9.23100   -9.58236  -18.66450 1.000 553.51260 ? 60  THR b CA  1 
ATOM 702  C C   . THR B 2 60  ? 7.90300   -9.35336  -17.95550 1.000 553.51260 ? 60  THR b C   1 
ATOM 703  O O   . THR B 2 60  ? 7.67100   -8.27436  -17.41450 1.000 553.51260 ? 60  THR b O   1 
ATOM 704  C CB  . THR B 2 60  ? 10.30100  -10.01936 -17.66050 1.000 553.51260 ? 60  THR b CB  1 
ATOM 705  O OG1 . THR B 2 60  ? 11.29900  -8.99636  -17.55450 1.000 553.51260 ? 60  THR b OG1 1 
ATOM 706  C CG2 . THR B 2 60  ? 10.98300  -11.29636 -18.11950 1.000 553.51260 ? 60  THR b CG2 1 
ATOM 707  N N   . GLU B 2 61  ? 7.02200   -10.36236 -17.98650 1.000 449.03884 ? 61  GLU b N   1 
ATOM 708  C CA  . GLU B 2 61  ? 5.63700   -10.15936 -17.55950 1.000 449.03884 ? 61  GLU b CA  1 
ATOM 709  C C   . GLU B 2 61  ? 5.51900   -9.86636  -16.06950 1.000 449.03884 ? 61  GLU b C   1 
ATOM 710  O O   . GLU B 2 61  ? 4.73300   -8.99836  -15.66950 1.000 449.03884 ? 61  GLU b O   1 
ATOM 711  C CB  . GLU B 2 61  ? 4.79300   -11.38436 -17.90450 1.000 449.03884 ? 61  GLU b CB  1 
ATOM 712  C CG  . GLU B 2 61  ? 3.29900   -11.14036 -17.76450 1.000 449.03884 ? 61  GLU b CG  1 
ATOM 713  C CD  . GLU B 2 61  ? 2.47900   -12.03036 -18.66550 1.000 449.03884 ? 61  GLU b CD  1 
ATOM 714  O OE1 . GLU B 2 61  ? 1.24000   -11.87636 -18.69350 1.000 449.03884 ? 61  GLU b OE1 1 
ATOM 715  O OE2 . GLU B 2 61  ? 3.08000   -12.88736 -19.33950 1.000 449.03884 ? 61  GLU b OE2 1 
ATOM 716  N N   . GLU B 2 62  ? 6.29600   -10.56136 -15.23950 1.000 447.32071 ? 62  GLU b N   1 
ATOM 717  C CA  . GLU B 2 62  ? 6.19400   -10.38336 -13.79750 1.000 447.32071 ? 62  GLU b CA  1 
ATOM 718  C C   . GLU B 2 62  ? 7.32100   -9.51536  -13.24150 1.000 447.32071 ? 62  GLU b C   1 
ATOM 719  O O   . GLU B 2 62  ? 7.14800   -8.88336  -12.19350 1.000 447.32071 ? 62  GLU b O   1 
ATOM 720  C CB  . GLU B 2 62  ? 6.13300   -11.73436 -13.03750 1.000 447.32071 ? 62  GLU b CB  1 
ATOM 721  C CG  . GLU B 2 62  ? 6.13200   -13.23336 -13.65850 1.000 447.32071 ? 62  GLU b CG  1 
ATOM 722  C CD  . GLU B 2 62  ? 6.81900   -13.57136 -15.00550 1.000 447.32071 ? 62  GLU b CD  1 
ATOM 723  O OE1 . GLU B 2 62  ? 7.22700   -12.68136 -15.77650 1.000 447.32071 ? 62  GLU b OE1 1 
ATOM 724  O OE2 . GLU B 2 62  ? 6.94500   -14.78536 -15.29750 1.000 447.32071 ? 62  GLU b OE2 1 
ATOM 725  N N   . GLU B 2 63  ? 8.47300   -9.46736  -13.91350 1.000 583.32633 ? 63  GLU b N   1 
ATOM 726  C CA  . GLU B 2 63  ? 9.55400   -8.59236  -13.47350 1.000 583.32633 ? 63  GLU b CA  1 
ATOM 727  C C   . GLU B 2 63  ? 9.22500   -7.12736  -13.73750 1.000 583.32633 ? 63  GLU b C   1 
ATOM 728  O O   . GLU B 2 63  ? 9.72200   -6.25136  -13.02050 1.000 583.32633 ? 63  GLU b O   1 
ATOM 729  C CB  . GLU B 2 63  ? 10.86400  -9.02936  -14.15550 1.000 583.32633 ? 63  GLU b CB  1 
ATOM 730  C CG  . GLU B 2 63  ? 12.11300  -8.15736  -13.95250 1.000 583.32633 ? 63  GLU b CG  1 
ATOM 731  C CD  . GLU B 2 63  ? 12.24400  -7.06536  -15.00650 1.000 583.32633 ? 63  GLU b CD  1 
ATOM 732  O OE1 . GLU B 2 63  ? 13.09300  -6.16736  -14.84350 1.000 583.32633 ? 63  GLU b OE1 1 
ATOM 733  O OE2 . GLU B 2 63  ? 11.47900  -7.11736  -15.98950 1.000 583.32633 ? 63  GLU b OE2 1 
ATOM 734  N N   . PHE B 2 64  ? 8.36800   -6.84436  -14.71350 1.000 601.32959 ? 64  PHE b N   1 
ATOM 735  C CA  . PHE B 2 64  ? 7.86800   -5.48936  -14.92950 1.000 601.32959 ? 64  PHE b CA  1 
ATOM 736  C C   . PHE B 2 64  ? 7.00200   -5.10136  -13.74150 1.000 601.32959 ? 64  PHE b C   1 
ATOM 737  O O   . PHE B 2 64  ? 5.97100   -5.71436  -13.46150 1.000 601.32959 ? 64  PHE b O   1 
ATOM 738  C CB  . PHE B 2 64  ? 7.08600   -5.40736  -16.22750 1.000 601.32959 ? 64  PHE b CB  1 
ATOM 739  C CG  . PHE B 2 64  ? 6.17400   -4.24136  -16.31050 1.000 601.32959 ? 64  PHE b CG  1 
ATOM 740  C CD1 . PHE B 2 64  ? 6.67800   -2.96036  -16.46350 1.000 601.32959 ? 64  PHE b CD1 1 
ATOM 741  C CD2 . PHE B 2 64  ? 4.80300   -4.42636  -16.24950 1.000 601.32959 ? 64  PHE b CD2 1 
ATOM 742  C CE1 . PHE B 2 64  ? 5.82800   -1.88536  -16.55050 1.000 601.32959 ? 64  PHE b CE1 1 
ATOM 743  C CE2 . PHE B 2 64  ? 3.95100   -3.36036  -16.32850 1.000 601.32959 ? 64  PHE b CE2 1 
ATOM 744  C CZ  . PHE B 2 64  ? 4.46200   -2.08936  -16.47850 1.000 601.32959 ? 64  PHE b CZ  1 
ATOM 745  N N   . VAL B 2 65  ? 7.44400   -4.07336  -13.02650 1.000 545.62138 ? 65  VAL b N   1 
ATOM 746  C CA  . VAL B 2 65  ? 6.70100   -3.57936  -11.87450 1.000 545.62138 ? 65  VAL b CA  1 
ATOM 747  C C   . VAL B 2 65  ? 5.44800   -2.84636  -12.35050 1.000 545.62138 ? 65  VAL b C   1 
ATOM 748  O O   . VAL B 2 65  ? 5.42500   -2.22336  -13.41450 1.000 545.62138 ? 65  VAL b O   1 
ATOM 749  C CB  . VAL B 2 65  ? 7.60500   -2.69636  -10.97550 1.000 545.62138 ? 65  VAL b CB  1 
ATOM 750  C CG1 . VAL B 2 65  ? 9.03900   -2.66736  -11.50850 1.000 545.62138 ? 65  VAL b CG1 1 
ATOM 751  C CG2 . VAL B 2 65  ? 7.08400   -1.26136  -10.77950 1.000 545.62138 ? 65  VAL b CG2 1 
ATOM 752  N N   . GLU B 2 66  ? 4.37000   -2.98036  -11.57750 1.000 449.85457 ? 66  GLU b N   1 
ATOM 753  C CA  . GLU B 2 66  ? 3.08800   -2.42036  -11.97450 1.000 449.85457 ? 66  GLU b CA  1 
ATOM 754  C C   . GLU B 2 66  ? 3.08500   -0.89836  -11.83350 1.000 449.85457 ? 66  GLU b C   1 
ATOM 755  O O   . GLU B 2 66  ? 3.92200   -0.30436  -11.14750 1.000 449.85457 ? 66  GLU b O   1 
ATOM 756  C CB  . GLU B 2 66  ? 1.95800   -3.01636  -11.13350 1.000 449.85457 ? 66  GLU b CB  1 
ATOM 757  C CG  . GLU B 2 66  ? 1.68300   -4.49036  -11.38650 1.000 449.85457 ? 66  GLU b CG  1 
ATOM 758  C CD  . GLU B 2 66  ? 2.38500   -5.38536  -10.38450 1.000 449.85457 ? 66  GLU b CD  1 
ATOM 759  O OE1 . GLU B 2 66  ? 3.04300   -4.84536  -9.47050  1.000 449.85457 ? 66  GLU b OE1 1 
ATOM 760  O OE2 . GLU B 2 66  ? 2.26400   -6.62436  -10.49350 1.000 449.85457 ? 66  GLU b OE2 1 
ATOM 761  N N   . GLY B 2 67  ? 2.11800   -0.27136  -12.48750 1.000 427.82856 ? 67  GLY b N   1 
ATOM 762  C CA  . GLY B 2 67  ? 1.99200   1.17064   -12.42750 1.000 427.82856 ? 67  GLY b CA  1 
ATOM 763  C C   . GLY B 2 67  ? 1.07700   1.67664   -13.52650 1.000 427.82856 ? 67  GLY b C   1 
ATOM 764  O O   . GLY B 2 67  ? 0.25200   0.93764   -14.06250 1.000 427.82856 ? 67  GLY b O   1 
ATOM 765  N N   . ILE B 2 68  ? 1.24500   2.95764   -13.84250 1.000 413.68133 ? 68  ILE b N   1 
ATOM 766  C CA  . ILE B 2 68  ? 0.47900   3.60064   -14.90150 1.000 413.68133 ? 68  ILE b CA  1 
ATOM 767  C C   . ILE B 2 68  ? 1.17400   3.23564   -16.20650 1.000 413.68133 ? 68  ILE b C   1 
ATOM 768  O O   . ILE B 2 68  ? 2.03500   3.96264   -16.69650 1.000 413.68133 ? 68  ILE b O   1 
ATOM 769  C CB  . ILE B 2 68  ? 0.39300   5.11264   -14.70150 1.000 413.68133 ? 68  ILE b CB  1 
ATOM 770  C CG1 . ILE B 2 68  ? 0.13600   5.43064   -13.23050 1.000 413.68133 ? 68  ILE b CG1 1 
ATOM 771  C CG2 . ILE B 2 68  ? -0.69800  5.70664   -15.57950 1.000 413.68133 ? 68  ILE b CG2 1 
ATOM 772  C CD1 . ILE B 2 68  ? 0.14500   6.90064   -12.91450 1.000 413.68133 ? 68  ILE b CD1 1 
ATOM 773  N N   . TYR B 2 69  ? 0.81300   2.08264   -16.75750 1.000 570.13811 ? 69  TYR b N   1 
ATOM 774  C CA  . TYR B 2 69  ? 1.41800   1.58864   -17.98250 1.000 570.13811 ? 69  TYR b CA  1 
ATOM 775  C C   . TYR B 2 69  ? 0.34000   0.93164   -18.82450 1.000 570.13811 ? 69  TYR b C   1 
ATOM 776  O O   . TYR B 2 69  ? -0.77300  0.68264   -18.35250 1.000 570.13811 ? 69  TYR b O   1 
ATOM 777  C CB  . TYR B 2 69  ? 2.57000   0.62364   -17.69750 1.000 570.13811 ? 69  TYR b CB  1 
ATOM 778  C CG  . TYR B 2 69  ? 3.74800   1.30164   -17.03750 1.000 570.13811 ? 69  TYR b CG  1 
ATOM 779  C CD1 . TYR B 2 69  ? 3.91400   1.26664   -15.65650 1.000 570.13811 ? 69  TYR b CD1 1 
ATOM 780  C CD2 . TYR B 2 69  ? 4.67400   2.01164   -17.79150 1.000 570.13811 ? 69  TYR b CD2 1 
ATOM 781  C CE1 . TYR B 2 69  ? 4.98200   1.89964   -15.04950 1.000 570.13811 ? 69  TYR b CE1 1 
ATOM 782  C CE2 . TYR B 2 69  ? 5.74500   2.64864   -17.19450 1.000 570.13811 ? 69  TYR b CE2 1 
ATOM 783  C CZ  . TYR B 2 69  ? 5.89300   2.58864   -15.82350 1.000 570.13811 ? 69  TYR b CZ  1 
ATOM 784  O OH  . TYR B 2 69  ? 6.95700   3.22164   -15.22450 1.000 570.13811 ? 69  TYR b OH  1 
ATOM 785  N N   . LYS B 2 70  ? 0.68100   0.64464   -20.07750 1.000 593.95711 ? 70  LYS b N   1 
ATOM 786  C CA  . LYS B 2 70  ? -0.32100  0.55064   -21.12850 1.000 593.95711 ? 70  LYS b CA  1 
ATOM 787  C C   . LYS B 2 70  ? 0.20000   -0.33136  -22.25050 1.000 593.95711 ? 70  LYS b C   1 
ATOM 788  O O   . LYS B 2 70  ? 1.41200   -0.50536  -22.39250 1.000 593.95711 ? 70  LYS b O   1 
ATOM 789  C CB  . LYS B 2 70  ? -0.62900  1.95964   -21.64050 1.000 593.95711 ? 70  LYS b CB  1 
ATOM 790  C CG  . LYS B 2 70  ? -1.92400  2.17464   -22.38350 1.000 593.95711 ? 70  LYS b CG  1 
ATOM 791  C CD  . LYS B 2 70  ? -2.10900  3.67864   -22.54350 1.000 593.95711 ? 70  LYS b CD  1 
ATOM 792  C CE  . LYS B 2 70  ? -3.39500  4.03564   -23.24350 1.000 593.95711 ? 70  LYS b CE  1 
ATOM 793  N NZ  . LYS B 2 70  ? -3.57300  5.50864   -23.35650 1.000 593.95711 ? 70  LYS b NZ  1 
ATOM 794  N N   . VAL B 2 71  ? -0.71500  -0.91636  -23.02050 1.000 648.86512 ? 71  VAL b N   1 
ATOM 795  C CA  . VAL B 2 71  ? -0.38800  -1.43636  -24.34450 1.000 648.86512 ? 71  VAL b CA  1 
ATOM 796  C C   . VAL B 2 71  ? -1.17300  -0.58236  -25.33350 1.000 648.86512 ? 71  VAL b C   1 
ATOM 797  O O   . VAL B 2 71  ? -2.29800  -0.91936  -25.70250 1.000 648.86512 ? 71  VAL b O   1 
ATOM 798  C CB  . VAL B 2 71  ? -0.73200  -2.91936  -24.48650 1.000 648.86512 ? 71  VAL b CB  1 
ATOM 799  C CG1 . VAL B 2 71  ? -0.12000  -3.47136  -25.75950 1.000 648.86512 ? 71  VAL b CG1 1 
ATOM 800  C CG2 . VAL B 2 71  ? -0.25600  -3.70036  -23.27750 1.000 648.86512 ? 71  VAL b CG2 1 
ATOM 801  N N   . GLU B 2 72  ? -0.58500  0.52264   -25.76950 1.000 497.49028 ? 72  GLU b N   1 
ATOM 802  C CA  . GLU B 2 72  ? -1.31400  1.53164   -26.52150 1.000 497.49028 ? 72  GLU b CA  1 
ATOM 803  C C   . GLU B 2 72  ? -1.19800  1.26064   -28.01350 1.000 497.49028 ? 72  GLU b C   1 
ATOM 804  O O   . GLU B 2 72  ? -0.11900  0.92664   -28.50850 1.000 497.49028 ? 72  GLU b O   1 
ATOM 805  C CB  . GLU B 2 72  ? -0.79400  2.93364   -26.20050 1.000 497.49028 ? 72  GLU b CB  1 
ATOM 806  C CG  . GLU B 2 72  ? -1.77700  4.05264   -26.52750 1.000 497.49028 ? 72  GLU b CG  1 
ATOM 807  C CD  . GLU B 2 72  ? -1.25800  5.42164   -26.12150 1.000 497.49028 ? 72  GLU b CD  1 
ATOM 808  O OE1 . GLU B 2 72  ? -0.14300  5.78264   -26.55650 1.000 497.49028 ? 72  GLU b OE1 1 
ATOM 809  O OE2 . GLU B 2 72  ? -1.96000  6.14764   -25.38350 1.000 497.49028 ? 72  GLU b OE2 1 
ATOM 810  N N   . ILE B 2 73  ? -2.31400  1.39064   -28.71850 1.000 532.90198 ? 73  ILE b N   1 
ATOM 811  C CA  . ILE B 2 73  ? -2.32400  1.37864   -30.17450 1.000 532.90198 ? 73  ILE b CA  1 
ATOM 812  C C   . ILE B 2 73  ? -2.08500  2.82664   -30.61350 1.000 532.90198 ? 73  ILE b C   1 
ATOM 813  O O   . ILE B 2 73  ? -3.03100  3.58564   -30.84450 1.000 532.90198 ? 73  ILE b O   1 
ATOM 814  C CB  . ILE B 2 73  ? -3.64400  0.79764   -30.70650 1.000 532.90198 ? 73  ILE b CB  1 
ATOM 815  C CG1 . ILE B 2 73  ? -3.86400  -0.61936  -30.15350 1.000 532.90198 ? 73  ILE b CG1 1 
ATOM 816  C CG2 . ILE B 2 73  ? -3.66100  0.72364   -32.20350 1.000 532.90198 ? 73  ILE b CG2 1 
ATOM 817  C CD1 . ILE B 2 73  ? -5.05400  -1.37036  -30.76350 1.000 532.90198 ? 73  ILE b CD1 1 
ATOM 818  N N   . ASP B 2 74  ? -0.80900  3.21864   -30.71950 1.000 440.30399 ? 74  ASP b N   1 
ATOM 819  C CA  . ASP B 2 74  ? -0.42000  4.62864   -30.78150 1.000 440.30399 ? 74  ASP b CA  1 
ATOM 820  C C   . ASP B 2 74  ? -0.58100  5.17564   -32.19250 1.000 440.30399 ? 74  ASP b C   1 
ATOM 821  O O   . ASP B 2 74  ? -0.12700  4.56064   -33.16050 1.000 440.30399 ? 74  ASP b O   1 
ATOM 822  C CB  . ASP B 2 74  ? 1.02500   4.83464   -30.32450 1.000 440.30399 ? 74  ASP b CB  1 
ATOM 823  C CG  . ASP B 2 74  ? 1.57400   6.20164   -30.72950 1.000 440.30399 ? 74  ASP b CG  1 
ATOM 824  O OD1 . ASP B 2 74  ? 1.05400   7.22564   -30.24250 1.000 440.30399 ? 74  ASP b OD1 1 
ATOM 825  O OD2 . ASP B 2 74  ? 2.51600   6.25764   -31.54350 1.000 440.30399 ? 74  ASP b OD2 1 
ATOM 826  N N   . THR B 2 75  ? -1.20100  6.35064   -32.29950 1.000 543.09363 ? 75  THR b N   1 
ATOM 827  C CA  . THR B 2 75  ? -1.40400  6.94064   -33.61250 1.000 543.09363 ? 75  THR b CA  1 
ATOM 828  C C   . THR B 2 75  ? -0.13000  7.56864   -34.15050 1.000 543.09363 ? 75  THR b C   1 
ATOM 829  O O   . THR B 2 75  ? 0.06900   7.61064   -35.36750 1.000 543.09363 ? 75  THR b O   1 
ATOM 830  C CB  . THR B 2 75  ? -2.49700  7.99664   -33.55850 1.000 543.09363 ? 75  THR b CB  1 
ATOM 831  O OG1 . THR B 2 75  ? -1.94200  9.21664   -33.05750 1.000 543.09363 ? 75  THR b OG1 1 
ATOM 832  C CG2 . THR B 2 75  ? -3.59500  7.54664   -32.62850 1.000 543.09363 ? 75  THR b CG2 1 
ATOM 833  N N   . LYS B 2 76  ? 0.73900   8.05664   -33.26450 1.000 569.14185 ? 76  LYS b N   1 
ATOM 834  C CA  . LYS B 2 76  ? 1.90900   8.80164   -33.70950 1.000 569.14185 ? 76  LYS b CA  1 
ATOM 835  C C   . LYS B 2 76  ? 2.93200   7.91864   -34.41050 1.000 569.14185 ? 76  LYS b C   1 
ATOM 836  O O   . LYS B 2 76  ? 3.41400   8.27364   -35.49250 1.000 569.14185 ? 76  LYS b O   1 
ATOM 837  C CB  . LYS B 2 76  ? 2.54600   9.50964   -32.52050 1.000 569.14185 ? 76  LYS b CB  1 
ATOM 838  C CG  . LYS B 2 76  ? 4.01100   9.86064   -32.70250 1.000 569.14185 ? 76  LYS b CG  1 
ATOM 839  C CD  . LYS B 2 76  ? 4.71800   10.06064  -31.36950 1.000 569.14185 ? 76  LYS b CD  1 
ATOM 840  C CE  . LYS B 2 76  ? 4.46600   8.92064   -30.40350 1.000 569.14185 ? 76  LYS b CE  1 
ATOM 841  N NZ  . LYS B 2 76  ? 4.87200   7.64364   -31.00650 1.000 569.14185 ? 76  LYS b NZ  1 
ATOM 842  N N   . SER B 2 77  ? 3.24100   6.75664   -33.85250 1.000 571.92920 ? 77  SER b N   1 
ATOM 843  C CA  . SER B 2 77  ? 4.30800   5.93564   -34.40350 1.000 571.92920 ? 77  SER b CA  1 
ATOM 844  C C   . SER B 2 77  ? 3.81800   4.91364   -35.41650 1.000 571.92920 ? 77  SER b C   1 
ATOM 845  O O   . SER B 2 77  ? 4.58100   4.51964   -36.30350 1.000 571.92920 ? 77  SER b O   1 
ATOM 846  C CB  . SER B 2 77  ? 5.05800   5.23264   -33.27450 1.000 571.92920 ? 77  SER b CB  1 
ATOM 847  O OG  . SER B 2 77  ? 4.87200   3.83964   -33.31850 1.000 571.92920 ? 77  SER b OG  1 
ATOM 848  N N   . TYR B 2 78  ? 2.56300   4.47464   -35.31550 1.000 580.72279 ? 78  TYR b N   1 
ATOM 849  C CA  . TYR B 2 78  ? 2.05000   3.53664   -36.30450 1.000 580.72279 ? 78  TYR b CA  1 
ATOM 850  C C   . TYR B 2 78  ? 1.77600   4.22664   -37.62650 1.000 580.72279 ? 78  TYR b C   1 
ATOM 851  O O   . TYR B 2 78  ? 2.23100   3.76464   -38.67750 1.000 580.72279 ? 78  TYR b O   1 
ATOM 852  C CB  . TYR B 2 78  ? 0.77700   2.87564   -35.80850 1.000 580.72279 ? 78  TYR b CB  1 
ATOM 853  C CG  . TYR B 2 78  ? -0.01100  2.20664   -36.90850 1.000 580.72279 ? 78  TYR b CG  1 
ATOM 854  C CD1 . TYR B 2 78  ? 0.47500   1.07764   -37.54650 1.000 580.72279 ? 78  TYR b CD1 1 
ATOM 855  C CD2 . TYR B 2 78  ? -1.23000  2.71464   -37.32050 1.000 580.72279 ? 78  TYR b CD2 1 
ATOM 856  C CE1 . TYR B 2 78  ? -0.24400  0.45164   -38.53850 1.000 580.72279 ? 78  TYR b CE1 1 
ATOM 857  C CE2 . TYR B 2 78  ? -1.95900  2.10064   -38.31450 1.000 580.72279 ? 78  TYR b CE2 1 
ATOM 858  C CZ  . TYR B 2 78  ? -1.46100  0.96864   -38.92050 1.000 580.72279 ? 78  TYR b CZ  1 
ATOM 859  O OH  . TYR B 2 78  ? -2.17400  0.34964   -39.92050 1.000 580.72279 ? 78  TYR b OH  1 
ATOM 860  N N   . TRP B 2 79  ? 1.03400   5.33264   -37.59850 1.000 516.20787 ? 79  TRP b N   1 
ATOM 861  C CA  . TRP B 2 79  ? 0.67500   6.01364   -38.83250 1.000 516.20787 ? 79  TRP b CA  1 
ATOM 862  C C   . TRP B 2 79  ? 1.85300   6.74364   -39.46150 1.000 516.20787 ? 79  TRP b C   1 
ATOM 863  O O   . TRP B 2 79  ? 1.73800   7.18664   -40.60850 1.000 516.20787 ? 79  TRP b O   1 
ATOM 864  C CB  . TRP B 2 79  ? -0.47200  6.99564   -38.58850 1.000 516.20787 ? 79  TRP b CB  1 
ATOM 865  C CG  . TRP B 2 79  ? -1.74800  6.34964   -38.12750 1.000 516.20787 ? 79  TRP b CG  1 
ATOM 866  C CD1 . TRP B 2 79  ? -2.31100  6.46164   -36.89950 1.000 516.20787 ? 79  TRP b CD1 1 
ATOM 867  C CD2 . TRP B 2 79  ? -2.61800  5.50064   -38.88550 1.000 516.20787 ? 79  TRP b CD2 1 
ATOM 868  N NE1 . TRP B 2 79  ? -3.47100  5.73964   -36.83250 1.000 516.20787 ? 79  TRP b NE1 1 
ATOM 869  C CE2 . TRP B 2 79  ? -3.68500  5.13864   -38.04250 1.000 516.20787 ? 79  TRP b CE2 1 
ATOM 870  C CE3 . TRP B 2 79  ? -2.60100  5.01364   -40.19450 1.000 516.20787 ? 79  TRP b CE3 1 
ATOM 871  C CZ2 . TRP B 2 79  ? -4.72200  4.31364   -38.46450 1.000 516.20787 ? 79  TRP b CZ2 1 
ATOM 872  C CZ3 . TRP B 2 79  ? -3.63100  4.19064   -40.61050 1.000 516.20787 ? 79  TRP b CZ3 1 
ATOM 873  C CH2 . TRP B 2 79  ? -4.67200  3.84564   -39.74650 1.000 516.20787 ? 79  TRP b CH2 1 
ATOM 874  N N   . LYS B 2 80  ? 2.97300   6.87764   -38.74250 1.000 473.85958 ? 80  LYS b N   1 
ATOM 875  C CA  . LYS B 2 80  ? 4.22100   7.31764   -39.35750 1.000 473.85958 ? 80  LYS b CA  1 
ATOM 876  C C   . LYS B 2 80  ? 4.73400   6.29964   -40.36850 1.000 473.85958 ? 80  LYS b C   1 
ATOM 877  O O   . LYS B 2 80  ? 5.29200   6.68164   -41.40650 1.000 473.85958 ? 80  LYS b O   1 
ATOM 878  C CB  . LYS B 2 80  ? 5.26700   7.57764   -38.26750 1.000 473.85958 ? 80  LYS b CB  1 
ATOM 879  C CG  . LYS B 2 80  ? 6.68100   7.90364   -38.75950 1.000 473.85958 ? 80  LYS b CG  1 
ATOM 880  C CD  . LYS B 2 80  ? 6.71800   9.13464   -39.65850 1.000 473.85958 ? 80  LYS b CD  1 
ATOM 881  C CE  . LYS B 2 80  ? 6.43400   10.41164  -38.88850 1.000 473.85958 ? 80  LYS b CE  1 
ATOM 882  N NZ  . LYS B 2 80  ? 7.54900   10.75664  -37.96650 1.000 473.85958 ? 80  LYS b NZ  1 
ATOM 883  N N   . ALA B 2 81  ? 4.51700   5.00764   -40.10950 1.000 486.93573 ? 81  ALA b N   1 
ATOM 884  C CA  . ALA B 2 81  ? 4.94500   3.96964   -41.03950 1.000 486.93573 ? 81  ALA b CA  1 
ATOM 885  C C   . ALA B 2 81  ? 4.14200   3.97964   -42.33550 1.000 486.93573 ? 81  ALA b C   1 
ATOM 886  O O   . ALA B 2 81  ? 4.59800   3.41564   -43.33550 1.000 486.93573 ? 81  ALA b O   1 
ATOM 887  C CB  . ALA B 2 81  ? 4.84700   2.59664   -40.37450 1.000 486.93573 ? 81  ALA b CB  1 
ATOM 888  N N   . LEU B 2 82  ? 2.96900   4.60964   -42.34450 1.000 556.80305 ? 82  LEU b N   1 
ATOM 889  C CA  . LEU B 2 82  ? 2.17000   4.77164   -43.54950 1.000 556.80305 ? 82  LEU b CA  1 
ATOM 890  C C   . LEU B 2 82  ? 2.34900   6.13564   -44.20150 1.000 556.80305 ? 82  LEU b C   1 
ATOM 891  O O   . LEU B 2 82  ? 1.80200   6.36564   -45.28350 1.000 556.80305 ? 82  LEU b O   1 
ATOM 892  C CB  . LEU B 2 82  ? 0.68700   4.53264   -43.24150 1.000 556.80305 ? 82  LEU b CB  1 
ATOM 893  C CG  . LEU B 2 82  ? 0.30300   3.14764   -42.71350 1.000 556.80305 ? 82  LEU b CG  1 
ATOM 894  C CD1 . LEU B 2 82  ? 0.20500   3.10464   -41.20150 1.000 556.80305 ? 82  LEU b CD1 1 
ATOM 895  C CD2 . LEU B 2 82  ? -1.00300  2.68464   -43.34550 1.000 556.80305 ? 82  LEU b CD2 1 
ATOM 896  N N   . GLY B 2 83  ? 3.09400   7.04164   -43.57550 1.000 582.66691 ? 83  GLY b N   1 
ATOM 897  C CA  . GLY B 2 83  ? 3.41300   8.31664   -44.18250 1.000 582.66691 ? 83  GLY b CA  1 
ATOM 898  C C   . GLY B 2 83  ? 2.36300   9.39564   -44.04750 1.000 582.66691 ? 83  GLY b C   1 
ATOM 899  O O   . GLY B 2 83  ? 2.50300   10.44764  -44.67950 1.000 582.66691 ? 83  GLY b O   1 
ATOM 900  N N   . ILE B 2 84  ? 1.32900   9.18464   -43.24350 1.000 576.01204 ? 84  ILE b N   1 
ATOM 901  C CA  . ILE B 2 84  ? 0.30800   10.19464  -42.99950 1.000 576.01204 ? 84  ILE b CA  1 
ATOM 902  C C   . ILE B 2 84  ? 0.53700   10.81064  -41.62650 1.000 576.01204 ? 84  ILE b C   1 
ATOM 903  O O   . ILE B 2 84  ? 1.07900   10.17764  -40.71450 1.000 576.01204 ? 84  ILE b O   1 
ATOM 904  C CB  . ILE B 2 84  ? -1.10400  9.59464   -43.15150 1.000 576.01204 ? 84  ILE b CB  1 
ATOM 905  C CG1 . ILE B 2 84  ? -1.37900  8.55564   -42.06850 1.000 576.01204 ? 84  ILE b CG1 1 
ATOM 906  C CG2 . ILE B 2 84  ? -1.27000  9.00064   -44.54950 1.000 576.01204 ? 84  ILE b CG2 1 
ATOM 907  C CD1 . ILE B 2 84  ? -2.77000  8.03264   -42.11350 1.000 576.01204 ? 84  ILE b CD1 1 
ATOM 908  N N   . SER B 2 85  ? 0.16100   12.08464  -41.49550 1.000 693.08617 ? 85  SER b N   1 
ATOM 909  C CA  . SER B 2 85  ? 0.49400   12.86564  -40.30750 1.000 693.08617 ? 85  SER b CA  1 
ATOM 910  C C   . SER B 2 85  ? -0.48800  12.55964  -39.18750 1.000 693.08617 ? 85  SER b C   1 
ATOM 911  O O   . SER B 2 85  ? -1.70200  12.67564  -39.39150 1.000 693.08617 ? 85  SER b O   1 
ATOM 912  C CB  . SER B 2 85  ? 0.48400   14.35764  -40.62250 1.000 693.08617 ? 85  SER b CB  1 
ATOM 913  O OG  . SER B 2 85  ? -0.32200  15.06964  -39.71250 1.000 693.08617 ? 85  SER b OG  1 
ATOM 914  N N   . PRO B 2 86  ? -0.02700  12.13664  -38.01650 1.000 655.35934 ? 86  PRO b N   1 
ATOM 915  C CA  . PRO B 2 86  ? -0.90800  11.94864  -36.86350 1.000 655.35934 ? 86  PRO b CA  1 
ATOM 916  C C   . PRO B 2 86  ? -0.92600  13.20364  -35.99750 1.000 655.35934 ? 86  PRO b C   1 
ATOM 917  O O   . PRO B 2 86  ? -0.15400  14.13664  -36.20050 1.000 655.35934 ? 86  PRO b O   1 
ATOM 918  C CB  . PRO B 2 86  ? -0.27000  10.76564  -36.12150 1.000 655.35934 ? 86  PRO b CB  1 
ATOM 919  C CG  . PRO B 2 86  ? 1.02300   10.44464  -36.86650 1.000 655.35934 ? 86  PRO b CG  1 
ATOM 920  C CD  . PRO B 2 86  ? 1.31000   11.59364  -37.76250 1.000 655.35934 ? 86  PRO b CD  1 
ATOM 921  N N   . PHE B 2 87  ? -1.85400  13.23564  -35.04450 1.000 585.26771 ? 87  PHE b N   1 
ATOM 922  C CA  . PHE B 2 87  ? -1.88200  14.29064  -34.03950 1.000 585.26771 ? 87  PHE b CA  1 
ATOM 923  C C   . PHE B 2 87  ? -1.82900  13.75264  -32.61750 1.000 585.26771 ? 87  PHE b C   1 
ATOM 924  O O   . PHE B 2 87  ? -1.15900  14.33964  -31.76450 1.000 585.26771 ? 87  PHE b O   1 
ATOM 925  C CB  . PHE B 2 87  ? -3.12100  15.18164  -34.25150 1.000 585.26771 ? 87  PHE b CB  1 
ATOM 926  C CG  . PHE B 2 87  ? -3.62800  15.86764  -33.00950 1.000 585.26771 ? 87  PHE b CG  1 
ATOM 927  C CD1 . PHE B 2 87  ? -2.92600  16.91764  -32.43050 1.000 585.26771 ? 87  PHE b CD1 1 
ATOM 928  C CD2 . PHE B 2 87  ? -4.84200  15.49464  -32.45250 1.000 585.26771 ? 87  PHE b CD2 1 
ATOM 929  C CE1 . PHE B 2 87  ? -3.40700  17.54664  -31.29650 1.000 585.26771 ? 87  PHE b CE1 1 
ATOM 930  C CE2 . PHE B 2 87  ? -5.33200  16.12864  -31.32950 1.000 585.26771 ? 87  PHE b CE2 1 
ATOM 931  C CZ  . PHE B 2 87  ? -4.61200  17.15064  -30.74750 1.000 585.26771 ? 87  PHE b CZ  1 
ATOM 932  N N   . HIS B 2 88  ? -2.50600  12.64864  -32.33050 1.000 547.16444 ? 88  HIS b N   1 
ATOM 933  C CA  . HIS B 2 88  ? -2.52700  12.14264  -30.96050 1.000 547.16444 ? 88  HIS b CA  1 
ATOM 934  C C   . HIS B 2 88  ? -1.36200  11.19164  -30.72550 1.000 547.16444 ? 88  HIS b C   1 
ATOM 935  O O   . HIS B 2 88  ? -1.47700  9.97664   -30.89450 1.000 547.16444 ? 88  HIS b O   1 
ATOM 936  C CB  . HIS B 2 88  ? -3.86100  11.48064  -30.65350 1.000 547.16444 ? 88  HIS b CB  1 
ATOM 937  C CG  . HIS B 2 88  ? -4.83600  12.39164  -29.97750 1.000 547.16444 ? 88  HIS b CG  1 
ATOM 938  N ND1 . HIS B 2 88  ? -6.18800  12.12864  -29.91850 1.000 547.16444 ? 88  HIS b ND1 1 
ATOM 939  C CD2 . HIS B 2 88  ? -4.65000  13.54764  -29.29950 1.000 547.16444 ? 88  HIS b CD2 1 
ATOM 940  C CE1 . HIS B 2 88  ? -6.79500  13.09664  -29.25750 1.000 547.16444 ? 88  HIS b CE1 1 
ATOM 941  N NE2 . HIS B 2 88  ? -5.88400  13.96964  -28.86850 1.000 547.16444 ? 88  HIS b NE2 1 
ATOM 942  N N   . GLU B 2 89  ? -0.22400  11.76264  -30.34450 1.000 592.93252 ? 89  GLU b N   1 
ATOM 943  C CA  . GLU B 2 89  ? 0.81700   10.98964  -29.68050 1.000 592.93252 ? 89  GLU b CA  1 
ATOM 944  C C   . GLU B 2 89  ? 0.34400   10.51164  -28.31650 1.000 592.93252 ? 89  GLU b C   1 
ATOM 945  O O   . GLU B 2 89  ? 0.66400   9.39664   -27.89350 1.000 592.93252 ? 89  GLU b O   1 
ATOM 946  C CB  . GLU B 2 89  ? 2.08800   11.83964  -29.61350 1.000 592.93252 ? 89  GLU b CB  1 
ATOM 947  C CG  . GLU B 2 89  ? 2.66000   12.21864  -28.26350 1.000 592.93252 ? 89  GLU b CG  1 
ATOM 948  C CD  . GLU B 2 89  ? 2.34600   13.66764  -27.94150 1.000 592.93252 ? 89  GLU b CD  1 
ATOM 949  O OE1 . GLU B 2 89  ? 2.79300   14.17764  -26.89350 1.000 592.93252 ? 89  GLU b OE1 1 
ATOM 950  O OE2 . GLU B 2 89  ? 1.60600   14.29664  -28.73150 1.000 592.93252 ? 89  GLU b OE2 1 
ATOM 951  N N   . HIS B 2 90  ? -0.44900  11.32864  -27.63650 1.000 578.88520 ? 90  HIS b N   1 
ATOM 952  C CA  . HIS B 2 90  ? -1.29300  10.88764  -26.53950 1.000 578.88520 ? 90  HIS b CA  1 
ATOM 953  C C   . HIS B 2 90  ? -2.46900  11.84664  -26.46450 1.000 578.88520 ? 90  HIS b C   1 
ATOM 954  O O   . HIS B 2 90  ? -2.50600  12.86364  -27.16350 1.000 578.88520 ? 90  HIS b O   1 
ATOM 955  C CB  . HIS B 2 90  ? -0.53700  10.83364  -25.21350 1.000 578.88520 ? 90  HIS b CB  1 
ATOM 956  C CG  . HIS B 2 90  ? 0.14600   12.11164  -24.85750 1.000 578.88520 ? 90  HIS b CG  1 
ATOM 957  N ND1 . HIS B 2 90  ? -0.53200  13.22764  -24.41850 1.000 578.88520 ? 90  HIS b ND1 1 
ATOM 958  C CD2 . HIS B 2 90  ? 1.45700   12.43464  -24.82750 1.000 578.88520 ? 90  HIS b CD2 1 
ATOM 959  C CE1 . HIS B 2 90  ? 0.33300   14.18964  -24.15550 1.000 578.88520 ? 90  HIS b CE1 1 
ATOM 960  N NE2 . HIS B 2 90  ? 1.54700   13.73364  -24.39550 1.000 578.88520 ? 90  HIS b NE2 1 
ATOM 961  N N   . ALA B 2 91  ? -3.41800  11.53764  -25.59350 1.000 486.75121 ? 91  ALA b N   1 
ATOM 962  C CA  . ALA B 2 91  ? -4.60900  12.34764  -25.41850 1.000 486.75121 ? 91  ALA b CA  1 
ATOM 963  C C   . ALA B 2 91  ? -4.84200  12.58164  -23.93550 1.000 486.75121 ? 91  ALA b C   1 
ATOM 964  O O   . ALA B 2 91  ? -4.90600  11.63364  -23.14750 1.000 486.75121 ? 91  ALA b O   1 
ATOM 965  C CB  . ALA B 2 91  ? -5.82500  11.67964  -26.06150 1.000 486.75121 ? 91  ALA b CB  1 
ATOM 966  N N   . GLU B 2 92  ? -4.95600  13.85064  -23.56450 1.000 376.79783 ? 92  GLU b N   1 
ATOM 967  C CA  . GLU B 2 92  ? -5.17900  14.23764  -22.17950 1.000 376.79783 ? 92  GLU b CA  1 
ATOM 968  C C   . GLU B 2 92  ? -6.64100  14.00964  -21.82150 1.000 376.79783 ? 92  GLU b C   1 
ATOM 969  O O   . GLU B 2 92  ? -7.43900  14.95264  -21.82650 1.000 376.79783 ? 92  GLU b O   1 
ATOM 970  C CB  . GLU B 2 92  ? -4.81100  15.70664  -21.98150 1.000 376.79783 ? 92  GLU b CB  1 
ATOM 971  C CG  . GLU B 2 92  ? -3.33100  16.03564  -22.11350 1.000 376.79783 ? 92  GLU b CG  1 
ATOM 972  C CD  . GLU B 2 92  ? -2.86700  16.21264  -23.54650 1.000 376.79783 ? 92  GLU b CD  1 
ATOM 973  O OE1 . GLU B 2 92  ? -3.69200  16.09564  -24.47850 1.000 376.79783 ? 92  GLU b OE1 1 
ATOM 974  O OE2 . GLU B 2 92  ? -1.66600  16.47964  -23.73750 1.000 376.79783 ? 92  GLU b OE2 1 
ATOM 975  N N   . VAL B 2 93  ? -7.00100  12.76064  -21.52650 1.000 424.77084 ? 93  VAL b N   1 
ATOM 976  C CA  . VAL B 2 93  ? -8.35200  12.40764  -21.10050 1.000 424.77084 ? 93  VAL b CA  1 
ATOM 977  C C   . VAL B 2 93  ? -8.26800  11.74764  -19.72950 1.000 424.77084 ? 93  VAL b C   1 
ATOM 978  O O   . VAL B 2 93  ? -7.20700  11.24464  -19.33650 1.000 424.77084 ? 93  VAL b O   1 
ATOM 979  C CB  . VAL B 2 93  ? -9.09200  11.51964  -22.13450 1.000 424.77084 ? 93  VAL b CB  1 
ATOM 980  C CG1 . VAL B 2 93  ? -8.45700  11.60464  -23.49450 1.000 424.77084 ? 93  VAL b CG1 1 
ATOM 981  C CG2 . VAL B 2 93  ? -9.10000  10.04664  -21.74850 1.000 424.77084 ? 93  VAL b CG2 1 
ATOM 982  N N   . VAL B 2 94  ? -9.37200  11.80464  -18.99050 1.000 440.70049 ? 94  VAL b N   1 
ATOM 983  C CA  . VAL B 2 94  ? -9.48400  11.19564  -17.67150 1.000 440.70049 ? 94  VAL b CA  1 
ATOM 984  C C   . VAL B 2 94  ? -9.88800  9.73664   -17.84150 1.000 440.70049 ? 94  VAL b C   1 
ATOM 985  O O   . VAL B 2 94  ? -10.48900 9.35764   -18.85450 1.000 440.70049 ? 94  VAL b O   1 
ATOM 986  C CB  . VAL B 2 94  ? -10.47900 11.97364  -16.78650 1.000 440.70049 ? 94  VAL b CB  1 
ATOM 987  C CG1 . VAL B 2 94  ? -10.67500 13.37664  -17.33150 1.000 440.70049 ? 94  VAL b CG1 1 
ATOM 988  C CG2 . VAL B 2 94  ? -11.86100 11.28664  -16.68650 1.000 440.70049 ? 94  VAL b CG2 1 
ATOM 989  N N   . PHE B 2 95  ? -9.49900  8.90764   -16.87950 1.000 429.95955 ? 95  PHE b N   1 
ATOM 990  C CA  . PHE B 2 95  ? -9.91800  7.51764   -16.83850 1.000 429.95955 ? 95  PHE b CA  1 
ATOM 991  C C   . PHE B 2 95  ? -9.99100  7.10164   -15.37850 1.000 429.95955 ? 95  PHE b C   1 
ATOM 992  O O   . PHE B 2 95  ? -9.14300  7.48264   -14.56750 1.000 429.95955 ? 95  PHE b O   1 
ATOM 993  C CB  . PHE B 2 95  ? -8.97300  6.60964   -17.63950 1.000 429.95955 ? 95  PHE b CB  1 
ATOM 994  C CG  . PHE B 2 95  ? -7.61000  6.44764   -17.02850 1.000 429.95955 ? 95  PHE b CG  1 
ATOM 995  C CD1 . PHE B 2 95  ? -6.65900  7.44764   -17.15550 1.000 429.95955 ? 95  PHE b CD1 1 
ATOM 996  C CD2 . PHE B 2 95  ? -7.27100  5.28664   -16.34950 1.000 429.95955 ? 95  PHE b CD2 1 
ATOM 997  C CE1 . PHE B 2 95  ? -5.41100  7.30864   -16.60050 1.000 429.95955 ? 95  PHE b CE1 1 
ATOM 998  C CE2 . PHE B 2 95  ? -6.01500  5.13964   -15.79450 1.000 429.95955 ? 95  PHE b CE2 1 
ATOM 999  C CZ  . PHE B 2 95  ? -5.08400  6.15464   -15.92250 1.000 429.95955 ? 95  PHE b CZ  1 
ATOM 1000 N N   . THR B 2 96  ? -11.02700 6.34264   -15.04750 1.000 270.96510 ? 96  THR b N   1 
ATOM 1001 C CA  . THR B 2 96  ? -11.26900 5.91364   -13.67850 1.000 270.96510 ? 96  THR b CA  1 
ATOM 1002 C C   . THR B 2 96  ? -11.39700 4.39764   -13.63750 1.000 270.96510 ? 96  THR b C   1 
ATOM 1003 O O   . THR B 2 96  ? -11.95100 3.79264   -14.56150 1.000 270.96510 ? 96  THR b O   1 
ATOM 1004 C CB  . THR B 2 96  ? -12.52600 6.57564   -13.10950 1.000 270.96510 ? 96  THR b CB  1 
ATOM 1005 O OG1 . THR B 2 96  ? -13.11600 7.41964   -14.10650 1.000 270.96510 ? 96  THR b OG1 1 
ATOM 1006 C CG2 . THR B 2 96  ? -12.17600 7.41564   -11.88250 1.000 270.96510 ? 96  THR b CG2 1 
ATOM 1007 N N   . ALA B 2 97  ? -10.86100 3.79064   -12.57750 1.000 346.73694 ? 97  ALA b N   1 
ATOM 1008 C CA  . ALA B 2 97  ? -10.90700 2.34764   -12.38850 1.000 346.73694 ? 97  ALA b CA  1 
ATOM 1009 C C   . ALA B 2 97  ? -10.75400 2.01964   -10.90950 1.000 346.73694 ? 97  ALA b C   1 
ATOM 1010 O O   . ALA B 2 97  ? -10.44600 2.89664   -10.09650 1.000 346.73694 ? 97  ALA b O   1 
ATOM 1011 C CB  . ALA B 2 97  ? -9.81000  1.63664   -13.19550 1.000 346.73694 ? 97  ALA b CB  1 
ATOM 1012 N N   . ASN B 2 98  ? -11.00000 0.74464   -10.58050 1.000 558.53048 ? 98  ASN b N   1 
ATOM 1013 C CA  . ASN B 2 98  ? -10.63500 0.10964   -9.30650  1.000 558.53048 ? 98  ASN b CA  1 
ATOM 1014 C C   . ASN B 2 98  ? -11.27700 0.79964   -8.09850  1.000 558.53048 ? 98  ASN b C   1 
ATOM 1015 O O   . ASN B 2 98  ? -10.60600 1.38864   -7.24550  1.000 558.53048 ? 98  ASN b O   1 
ATOM 1016 C CB  . ASN B 2 98  ? -9.11000  0.03464   -9.15750  1.000 558.53048 ? 98  ASN b CB  1 
ATOM 1017 C CG  . ASN B 2 98  ? -8.61200  -1.39036  -9.00650  1.000 558.53048 ? 98  ASN b CG  1 
ATOM 1018 O OD1 . ASN B 2 98  ? -9.19200  -2.18636  -8.26850  1.000 558.53048 ? 98  ASN b OD1 1 
ATOM 1019 N ND2 . ASN B 2 98  ? -7.54700  -1.72536  -9.72350  1.000 558.53048 ? 98  ASN b ND2 1 
ATOM 1020 N N   . ASP B 2 99  ? -12.60800 0.72264   -8.05250  1.000 727.48874 ? 99  ASP b N   1 
ATOM 1021 C CA  . ASP B 2 99  ? -13.31800 1.14664   -6.85250  1.000 727.48874 ? 99  ASP b CA  1 
ATOM 1022 C C   . ASP B 2 99  ? -13.41000 0.01364   -5.83550  1.000 727.48874 ? 99  ASP b C   1 
ATOM 1023 O O   . ASP B 2 99  ? -13.19100 0.22564   -4.63850  1.000 727.48874 ? 99  ASP b O   1 
ATOM 1024 C CB  . ASP B 2 99  ? -14.70800 1.66764   -7.22150  1.000 727.48874 ? 99  ASP b CB  1 
ATOM 1025 C CG  . ASP B 2 99  ? -15.46000 0.72764   -8.14750  1.000 727.48874 ? 99  ASP b CG  1 
ATOM 1026 O OD1 . ASP B 2 99  ? -15.63600 1.07964   -9.32950  1.000 727.48874 ? 99  ASP b OD1 1 
ATOM 1027 O OD2 . ASP B 2 99  ? -15.88300 -0.35836  -7.70050  1.000 727.48874 ? 99  ASP b OD2 1 
ATOM 1028 N N   . SER B 2 100 ? -13.75000 -1.18936  -6.28750  1.000 758.48711 ? 100 SER b N   1 
ATOM 1029 C CA  . SER B 2 100 ? -13.84100 -2.33936  -5.39650  1.000 758.48711 ? 100 SER b CA  1 
ATOM 1030 C C   . SER B 2 100 ? -13.30800 -3.59436  -6.07250  1.000 758.48711 ? 100 SER b C   1 
ATOM 1031 O O   . SER B 2 100 ? -13.89100 -4.67636  -5.94950  1.000 758.48711 ? 100 SER b O   1 
ATOM 1032 C CB  . SER B 2 100 ? -15.27600 -2.55436  -4.91850  1.000 758.48711 ? 100 SER b CB  1 
ATOM 1033 O OG  . SER B 2 100 ? -15.68000 -1.52636  -4.02750  1.000 758.48711 ? 100 SER b OG  1 
ATOM 1034 N N   . GLY B 2 101 ? -12.19600 -3.47836  -6.79450  1.000 740.23474 ? 101 GLY b N   1 
ATOM 1035 C CA  . GLY B 2 101 ? -11.55900 -4.63936  -7.37050  1.000 740.23474 ? 101 GLY b CA  1 
ATOM 1036 C C   . GLY B 2 101 ? -11.22100 -4.49836  -8.84150  1.000 740.23474 ? 101 GLY b C   1 
ATOM 1037 O O   . GLY B 2 101 ? -11.91500 -3.81836  -9.60350  1.000 740.23474 ? 101 GLY b O   1 
ATOM 1038 N N   . PRO B 2 102 ? -10.14200 -5.15936  -9.27150  1.000 632.55367 ? 102 PRO b N   1 
ATOM 1039 C CA  . PRO B 2 102 ? -9.66400  -4.99036  -10.64950 1.000 632.55367 ? 102 PRO b CA  1 
ATOM 1040 C C   . PRO B 2 102 ? -10.35700 -5.93536  -11.62250 1.000 632.55367 ? 102 PRO b C   1 
ATOM 1041 O O   . PRO B 2 102 ? -10.69800 -7.07136  -11.28250 1.000 632.55367 ? 102 PRO b O   1 
ATOM 1042 C CB  . PRO B 2 102 ? -8.16800  -5.31036  -10.53950 1.000 632.55367 ? 102 PRO b CB  1 
ATOM 1043 C CG  . PRO B 2 102 ? -8.09300  -6.30836  -9.42450  1.000 632.55367 ? 102 PRO b CG  1 
ATOM 1044 C CD  . PRO B 2 102 ? -9.23100  -5.99936  -8.47050  1.000 632.55367 ? 102 PRO b CD  1 
ATOM 1045 N N   . ARG B 2 103 ? -10.57200 -5.45236  -12.84150 1.000 452.01628 ? 103 ARG b N   1 
ATOM 1046 C CA  . ARG B 2 103 ? -11.09200 -6.25836  -13.93650 1.000 452.01628 ? 103 ARG b CA  1 
ATOM 1047 C C   . ARG B 2 103 ? -10.11200 -6.23236  -15.10550 1.000 452.01628 ? 103 ARG b C   1 
ATOM 1048 O O   . ARG B 2 103 ? -9.04600  -5.61436  -15.04150 1.000 452.01628 ? 103 ARG b O   1 
ATOM 1049 C CB  . ARG B 2 103 ? -12.47500 -5.76836  -14.37850 1.000 452.01628 ? 103 ARG b CB  1 
ATOM 1050 C CG  . ARG B 2 103 ? -13.55600 -5.86136  -13.30750 1.000 452.01628 ? 103 ARG b CG  1 
ATOM 1051 C CD  . ARG B 2 103 ? -13.79800 -7.29936  -12.84750 1.000 452.01628 ? 103 ARG b CD  1 
ATOM 1052 N NE  . ARG B 2 103 ? -14.79400 -7.36236  -11.77850 1.000 452.01628 ? 103 ARG b NE  1 
ATOM 1053 C CZ  . ARG B 2 103 ? -14.98400 -8.40836  -10.97950 1.000 452.01628 ? 103 ARG b CZ  1 
ATOM 1054 N NH1 . ARG B 2 103 ? -14.25000 -9.50436  -11.12050 1.000 452.01628 ? 103 ARG b NH1 1 
ATOM 1055 N NH2 . ARG B 2 103 ? -15.91700 -8.35936  -10.03950 1.000 452.01628 ? 103 ARG b NH2 1 
ATOM 1056 N N   . ARG B 2 104 ? -10.49300 -6.90636  -16.19050 1.000 484.73551 ? 104 ARG b N   1 
ATOM 1057 C CA  . ARG B 2 104 ? -9.63900  -7.07836  -17.36350 1.000 484.73551 ? 104 ARG b CA  1 
ATOM 1058 C C   . ARG B 2 104 ? -10.22300 -6.32936  -18.55650 1.000 484.73551 ? 104 ARG b C   1 
ATOM 1059 O O   . ARG B 2 104 ? -11.06600 -6.86536  -19.28250 1.000 484.73551 ? 104 ARG b O   1 
ATOM 1060 C CB  . ARG B 2 104 ? -9.45600  -8.55536  -17.70250 1.000 484.73551 ? 104 ARG b CB  1 
ATOM 1061 C CG  . ARG B 2 104 ? -8.31600  -8.80536  -18.67350 1.000 484.73551 ? 104 ARG b CG  1 
ATOM 1062 C CD  . ARG B 2 104 ? -8.81000  -9.06736  -20.10050 1.000 484.73551 ? 104 ARG b CD  1 
ATOM 1063 N NE  . ARG B 2 104 ? -9.61000  -10.28136 -20.20950 1.000 484.73551 ? 104 ARG b NE  1 
ATOM 1064 C CZ  . ARG B 2 104 ? -10.49700 -10.50036 -21.17250 1.000 484.73551 ? 104 ARG b CZ  1 
ATOM 1065 N NH1 . ARG B 2 104 ? -10.70200 -9.58336  -22.10750 1.000 484.73551 ? 104 ARG b NH1 1 
ATOM 1066 N NH2 . ARG B 2 104 ? -11.18300 -11.63436 -21.20250 1.000 484.73551 ? 104 ARG b NH2 1 
ATOM 1067 N N   . TYR B 2 105 ? -9.81200  -5.07936  -18.73350 1.000 505.45422 ? 105 TYR b N   1 
ATOM 1068 C CA  . TYR B 2 105 ? -9.91600  -4.39436  -20.01550 1.000 505.45422 ? 105 TYR b CA  1 
ATOM 1069 C C   . TYR B 2 105 ? -8.73600  -3.44636  -20.17650 1.000 505.45422 ? 105 TYR b C   1 
ATOM 1070 O O   . TYR B 2 105 ? -8.55100  -2.52236  -19.37850 1.000 505.45422 ? 105 TYR b O   1 
ATOM 1071 C CB  . TYR B 2 105 ? -11.25100 -3.62036  -20.29550 1.000 505.45422 ? 105 TYR b CB  1 
ATOM 1072 C CG  . TYR B 2 105 ? -12.52300 -3.60636  -19.40850 1.000 505.45422 ? 105 TYR b CG  1 
ATOM 1073 C CD1 . TYR B 2 105 ? -12.56300 -3.96236  -18.05350 1.000 505.45422 ? 105 TYR b CD1 1 
ATOM 1074 C CD2 . TYR B 2 105 ? -13.72800 -3.23636  -19.99950 1.000 505.45422 ? 105 TYR b CD2 1 
ATOM 1075 C CE1 . TYR B 2 105 ? -13.74700 -3.94336  -17.34150 1.000 505.45422 ? 105 TYR b CE1 1 
ATOM 1076 C CE2 . TYR B 2 105 ? -14.90400 -3.20836  -19.29250 1.000 505.45422 ? 105 TYR b CE2 1 
ATOM 1077 C CZ  . TYR B 2 105 ? -14.91000 -3.56036  -17.96850 1.000 505.45422 ? 105 TYR b CZ  1 
ATOM 1078 O OH  . TYR B 2 105 ? -16.09800 -3.52736  -17.27950 1.000 505.45422 ? 105 TYR b OH  1 
ATOM 1079 N N   . THR B 2 106 ? -7.94100  -3.68636  -21.21550 1.000 350.30667 ? 106 THR b N   1 
ATOM 1080 C CA  . THR B 2 106 ? -6.73000  -2.92636  -21.49750 1.000 350.30667 ? 106 THR b CA  1 
ATOM 1081 C C   . THR B 2 106 ? -7.02400  -2.00936  -22.68250 1.000 350.30667 ? 106 THR b C   1 
ATOM 1082 O O   . THR B 2 106 ? -7.87800  -2.32836  -23.51750 1.000 350.30667 ? 106 THR b O   1 
ATOM 1083 C CB  . THR B 2 106 ? -5.56000  -3.88636  -21.77650 1.000 350.30667 ? 106 THR b CB  1 
ATOM 1084 O OG1 . THR B 2 106 ? -5.49200  -4.86536  -20.72950 1.000 350.30667 ? 106 THR b OG1 1 
ATOM 1085 C CG2 . THR B 2 106 ? -4.20700  -3.17036  -21.81250 1.000 350.30667 ? 106 THR b CG2 1 
ATOM 1086 N N   . ILE B 2 107 ? -6.33400  -0.87036  -22.75150 1.000 184.54183 ? 107 ILE b N   1 
ATOM 1087 C CA  . ILE B 2 107 ? -6.65800  0.17564   -23.71550 1.000 184.54183 ? 107 ILE b CA  1 
ATOM 1088 C C   . ILE B 2 107 ? -6.11800  -0.16736  -25.09850 1.000 184.54183 ? 107 ILE b C   1 
ATOM 1089 O O   . ILE B 2 107 ? -4.97600  0.16764   -25.43450 1.000 184.54183 ? 107 ILE b O   1 
ATOM 1090 C CB  . ILE B 2 107 ? -6.11100  1.53464   -23.24550 1.000 184.54183 ? 107 ILE b CB  1 
ATOM 1091 C CG1 . ILE B 2 107 ? -6.34400  1.72464   -21.74350 1.000 184.54183 ? 107 ILE b CG1 1 
ATOM 1092 C CG2 . ILE B 2 107 ? -6.73600  2.66864   -24.04550 1.000 184.54183 ? 107 ILE b CG2 1 
ATOM 1093 C CD1 . ILE B 2 107 ? -7.79300  1.90064   -21.35550 1.000 184.54183 ? 107 ILE b CD1 1 
ATOM 1094 N N   . ALA B 2 108 ? -6.93800  -0.83036  -25.90950 1.000 290.62388 ? 108 ALA b N   1 
ATOM 1095 C CA  . ALA B 2 108 ? -6.66700  -1.01836  -27.32550 1.000 290.62388 ? 108 ALA b CA  1 
ATOM 1096 C C   . ALA B 2 108 ? -7.28600  0.14364   -28.08450 1.000 290.62388 ? 108 ALA b C   1 
ATOM 1097 O O   . ALA B 2 108 ? -8.50900  0.23364   -28.21050 1.000 290.62388 ? 108 ALA b O   1 
ATOM 1098 C CB  . ALA B 2 108 ? -7.23600  -2.34336  -27.83650 1.000 290.62388 ? 108 ALA b CB  1 
ATOM 1099 N N   . ALA B 2 109 ? -6.44300  1.03064   -28.59250 1.000 504.77937 ? 109 ALA b N   1 
ATOM 1100 C CA  . ALA B 2 109 ? -6.89500  2.34064   -29.02650 1.000 504.77937 ? 109 ALA b CA  1 
ATOM 1101 C C   . ALA B 2 109 ? -7.52400  2.27364   -30.41050 1.000 504.77937 ? 109 ALA b C   1 
ATOM 1102 O O   . ALA B 2 109 ? -7.23300  1.35864   -31.18750 1.000 504.77937 ? 109 ALA b O   1 
ATOM 1103 C CB  . ALA B 2 109 ? -5.75000  3.35064   -29.02150 1.000 504.77937 ? 109 ALA b CB  1 
ATOM 1104 N N   . LEU B 2 110 ? -8.40300  3.23764   -30.69650 1.000 593.89106 ? 110 LEU b N   1 
ATOM 1105 C CA  . LEU B 2 110 ? -8.96900  3.41864   -32.02950 1.000 593.89106 ? 110 LEU b CA  1 
ATOM 1106 C C   . LEU B 2 110 ? -7.87500  3.83564   -32.98850 1.000 593.89106 ? 110 LEU b C   1 
ATOM 1107 O O   . LEU B 2 110 ? -7.25200  4.88764   -32.81950 1.000 593.89106 ? 110 LEU b O   1 
ATOM 1108 C CB  . LEU B 2 110 ? -10.07300 4.47064   -32.03250 1.000 593.89106 ? 110 LEU b CB  1 
ATOM 1109 C CG  . LEU B 2 110 ? -10.49700 5.00964   -33.40850 1.000 593.89106 ? 110 LEU b CG  1 
ATOM 1110 C CD1 . LEU B 2 110 ? -11.16500 3.93564   -34.24950 1.000 593.89106 ? 110 LEU b CD1 1 
ATOM 1111 C CD2 . LEU B 2 110 ? -11.39500 6.23464   -33.29250 1.000 593.89106 ? 110 LEU b CD2 1 
ATOM 1112 N N   . LEU B 2 111 ? -7.64300  3.02264   -34.00150 1.000 560.52471 ? 111 LEU b N   1 
ATOM 1113 C CA  . LEU B 2 111 ? -6.80300  3.46264   -35.09450 1.000 560.52471 ? 111 LEU b CA  1 
ATOM 1114 C C   . LEU B 2 111 ? -7.53000  4.52664   -35.89650 1.000 560.52471 ? 111 LEU b C   1 
ATOM 1115 O O   . LEU B 2 111 ? -8.30000  4.21664   -36.80550 1.000 560.52471 ? 111 LEU b O   1 
ATOM 1116 C CB  . LEU B 2 111 ? -6.40800  2.29664   -35.98750 1.000 560.52471 ? 111 LEU b CB  1 
ATOM 1117 C CG  . LEU B 2 111 ? -5.13400  1.60764   -35.52550 1.000 560.52471 ? 111 LEU b CG  1 
ATOM 1118 C CD1 . LEU B 2 111 ? -4.71300  0.61564   -36.56750 1.000 560.52471 ? 111 LEU b CD1 1 
ATOM 1119 C CD2 . LEU B 2 111 ? -4.05500  2.64164   -35.28450 1.000 560.52471 ? 111 LEU b CD2 1 
ATOM 1120 N N   . SER B 2 112 ? -7.27700  5.77764   -35.55650 1.000 571.85501 ? 112 SER b N   1 
ATOM 1121 C CA  . SER B 2 112 ? -7.52400  6.88964   -36.44750 1.000 571.85501 ? 112 SER b CA  1 
ATOM 1122 C C   . SER B 2 112 ? -6.17900  7.55964   -36.61650 1.000 571.85501 ? 112 SER b C   1 
ATOM 1123 O O   . SER B 2 112 ? -5.29900  7.40964   -35.75250 1.000 571.85501 ? 112 SER b O   1 
ATOM 1124 C CB  . SER B 2 112 ? -8.56600  7.87164   -35.88750 1.000 571.85501 ? 112 SER b CB  1 
ATOM 1125 O OG  . SER B 2 112 ? -8.76500  7.65364   -34.51050 1.000 571.85501 ? 112 SER b OG  1 
ATOM 1126 N N   . PRO B 2 113 ? -5.94500  8.25064   -37.73950 1.000 533.67518 ? 113 PRO b N   1 
ATOM 1127 C CA  . PRO B 2 113 ? -4.63800  8.89464   -37.93750 1.000 533.67518 ? 113 PRO b CA  1 
ATOM 1128 C C   . PRO B 2 113 ? -4.33200  9.97564   -36.91950 1.000 533.67518 ? 113 PRO b C   1 
ATOM 1129 O O   . PRO B 2 113 ? -3.35200  9.85364   -36.17950 1.000 533.67518 ? 113 PRO b O   1 
ATOM 1130 C CB  . PRO B 2 113 ? -4.74600  9.45964   -39.35850 1.000 533.67518 ? 113 PRO b CB  1 
ATOM 1131 C CG  . PRO B 2 113 ? -5.76900  8.58964   -40.02450 1.000 533.67518 ? 113 PRO b CG  1 
ATOM 1132 C CD  . PRO B 2 113 ? -6.76000  8.27564   -38.96850 1.000 533.67518 ? 113 PRO b CD  1 
ATOM 1133 N N   . TYR B 2 114 ? -5.17800  10.98764  -36.80250 1.000 638.77633 ? 114 TYR b N   1 
ATOM 1134 C CA  . TYR B 2 114 ? -4.90400  12.09764  -35.90750 1.000 638.77633 ? 114 TYR b CA  1 
ATOM 1135 C C   . TYR B 2 114 ? -5.32400  11.82964  -34.47250 1.000 638.77633 ? 114 TYR b C   1 
ATOM 1136 O O   . TYR B 2 114 ? -4.88200  12.54464  -33.57550 1.000 638.77633 ? 114 TYR b O   1 
ATOM 1137 C CB  . TYR B 2 114 ? -5.59900  13.36164  -36.41650 1.000 638.77633 ? 114 TYR b CB  1 
ATOM 1138 C CG  . TYR B 2 114 ? -5.01500  13.88864  -37.69550 1.000 638.77633 ? 114 TYR b CG  1 
ATOM 1139 C CD1 . TYR B 2 114 ? -5.52700  13.50064  -38.92150 1.000 638.77633 ? 114 TYR b CD1 1 
ATOM 1140 C CD2 . TYR B 2 114 ? -3.96900  14.79864  -37.67350 1.000 638.77633 ? 114 TYR b CD2 1 
ATOM 1141 C CE1 . TYR B 2 114 ? -4.99600  13.98564  -40.09250 1.000 638.77633 ? 114 TYR b CE1 1 
ATOM 1142 C CE2 . TYR B 2 114 ? -3.43800  15.29464  -38.82950 1.000 638.77633 ? 114 TYR b CE2 1 
ATOM 1143 C CZ  . TYR B 2 114 ? -3.95700  14.87764  -40.04150 1.000 638.77633 ? 114 TYR b CZ  1 
ATOM 1144 O OH  . TYR B 2 114 ? -3.42800  15.36564  -41.20650 1.000 638.77633 ? 114 TYR b OH  1 
ATOM 1145 N N   . SER B 2 115 ? -6.14600  10.81864  -34.21950 1.000 583.97476 ? 115 SER b N   1 
ATOM 1146 C CA  . SER B 2 115 ? -6.71700  10.69864  -32.88750 1.000 583.97476 ? 115 SER b CA  1 
ATOM 1147 C C   . SER B 2 115 ? -6.90100  9.23764   -32.52350 1.000 583.97476 ? 115 SER b C   1 
ATOM 1148 O O   . SER B 2 115 ? -6.66800  8.33864   -33.33250 1.000 583.97476 ? 115 SER b O   1 
ATOM 1149 C CB  . SER B 2 115 ? -8.05300  11.43164  -32.78850 1.000 583.97476 ? 115 SER b CB  1 
ATOM 1150 O OG  . SER B 2 115 ? -8.43900  11.95264  -34.04250 1.000 583.97476 ? 115 SER b OG  1 
ATOM 1151 N N   . TYR B 2 116 ? -7.33800  9.01764   -31.28650 1.000 515.55968 ? 116 TYR b N   1 
ATOM 1152 C CA  . TYR B 2 116 ? -7.71300  7.68564   -30.84350 1.000 515.55968 ? 116 TYR b CA  1 
ATOM 1153 C C   . TYR B 2 116 ? -8.74100  7.76664   -29.72350 1.000 515.55968 ? 116 TYR b C   1 
ATOM 1154 O O   . TYR B 2 116 ? -8.58600  8.53364   -28.76650 1.000 515.55968 ? 116 TYR b O   1 
ATOM 1155 C CB  . TYR B 2 116 ? -6.48700  6.86564   -30.39850 1.000 515.55968 ? 116 TYR b CB  1 
ATOM 1156 C CG  . TYR B 2 116 ? -5.77400  7.37564   -29.17050 1.000 515.55968 ? 116 TYR b CG  1 
ATOM 1157 C CD1 . TYR B 2 116 ? -6.00700  6.82064   -27.91750 1.000 515.55968 ? 116 TYR b CD1 1 
ATOM 1158 C CD2 . TYR B 2 116 ? -4.84700  8.39964   -29.27250 1.000 515.55968 ? 116 TYR b CD2 1 
ATOM 1159 C CE1 . TYR B 2 116 ? -5.34700  7.29364   -26.79750 1.000 515.55968 ? 116 TYR b CE1 1 
ATOM 1160 C CE2 . TYR B 2 116 ? -4.18400  8.88164   -28.16550 1.000 515.55968 ? 116 TYR b CE2 1 
ATOM 1161 C CZ  . TYR B 2 116 ? -4.43500  8.32464   -26.92950 1.000 515.55968 ? 116 TYR b CZ  1 
ATOM 1162 O OH  . TYR B 2 116 ? -3.77400  8.79864   -25.82050 1.000 515.55968 ? 116 TYR b OH  1 
ATOM 1163 N N   . SER B 2 117 ? -9.80600  6.99264   -29.88050 1.000 495.89926 ? 117 SER b N   1 
ATOM 1164 C CA  . SER B 2 117 ? -10.61400 6.49764   -28.78150 1.000 495.89926 ? 117 SER b CA  1 
ATOM 1165 C C   . SER B 2 117 ? -10.14200 5.07764   -28.51150 1.000 495.89926 ? 117 SER b C   1 
ATOM 1166 O O   . SER B 2 117 ? -9.06600  4.68564   -28.95250 1.000 495.89926 ? 117 SER b O   1 
ATOM 1167 C CB  . SER B 2 117 ? -12.10800 6.56064   -29.09750 1.000 495.89926 ? 117 SER b CB  1 
ATOM 1168 O OG  . SER B 2 117 ? -12.44200 5.72664   -30.19650 1.000 495.89926 ? 117 SER b OG  1 
ATOM 1169 N N   . THR B 2 118 ? -10.90600 4.32264   -27.73750 1.000 474.05680 ? 118 THR b N   1 
ATOM 1170 C CA  . THR B 2 118 ? -10.52200 2.96064   -27.39650 1.000 474.05680 ? 118 THR b CA  1 
ATOM 1171 C C   . THR B 2 118 ? -11.45700 1.97364   -28.08150 1.000 474.05680 ? 118 THR b C   1 
ATOM 1172 O O   . THR B 2 118 ? -12.67600 2.04164   -27.89750 1.000 474.05680 ? 118 THR b O   1 
ATOM 1173 C CB  . THR B 2 118 ? -10.54900 2.76064   -25.88350 1.000 474.05680 ? 118 THR b CB  1 
ATOM 1174 O OG1 . THR B 2 118 ? -9.63200  3.67564   -25.27450 1.000 474.05680 ? 118 THR b OG1 1 
ATOM 1175 C CG2 . THR B 2 118 ? -10.13100 1.34864   -25.52950 1.000 474.05680 ? 118 THR b CG2 1 
ATOM 1176 N N   . THR B 2 119 ? -10.88700 1.06464   -28.87450 1.000 537.86839 ? 119 THR b N   1 
ATOM 1177 C CA  . THR B 2 119 ? -11.66200 0.08464   -29.62850 1.000 537.86839 ? 119 THR b CA  1 
ATOM 1178 C C   . THR B 2 119 ? -11.33500 -1.34236  -29.21150 1.000 537.86839 ? 119 THR b C   1 
ATOM 1179 O O   . THR B 2 119 ? -10.19500 -1.79536  -29.36150 1.000 537.86839 ? 119 THR b O   1 
ATOM 1180 C CB  . THR B 2 119 ? -11.42800 0.24364   -31.12850 1.000 537.86839 ? 119 THR b CB  1 
ATOM 1181 O OG1 . THR B 2 119 ? -10.01900 0.29964   -31.39650 1.000 537.86839 ? 119 THR b OG1 1 
ATOM 1182 C CG2 . THR B 2 119 ? -12.13100 1.47764   -31.63350 1.000 537.86839 ? 119 THR b CG2 1 
ATOM 1183 N N   . ALA B 2 120 ? -12.35800 -2.05836  -28.73950 1.000 579.46108 ? 120 ALA b N   1 
ATOM 1184 C CA  . ALA B 2 120 ? -12.25200 -3.44936  -28.32550 1.000 579.46108 ? 120 ALA b CA  1 
ATOM 1185 C C   . ALA B 2 120 ? -13.64100 -4.06836  -28.25350 1.000 579.46108 ? 120 ALA b C   1 
ATOM 1186 O O   . ALA B 2 120 ? -14.61700 -3.38936  -27.92750 1.000 579.46108 ? 120 ALA b O   1 
ATOM 1187 C CB  . ALA B 2 120 ? -11.55600 -3.58136  -26.96450 1.000 579.46108 ? 120 ALA b CB  1 
ATOM 1188 N N   . VAL B 2 121 ? -13.72000 -5.35536  -28.57150 1.000 379.76212 ? 121 VAL b N   1 
ATOM 1189 C CA  . VAL B 2 121 ? -14.90900 -6.17036  -28.35150 1.000 379.76212 ? 121 VAL b CA  1 
ATOM 1190 C C   . VAL B 2 121 ? -14.98900 -6.46936  -26.85650 1.000 379.76212 ? 121 VAL b C   1 
ATOM 1191 O O   . VAL B 2 121 ? -14.11800 -7.14336  -26.29850 1.000 379.76212 ? 121 VAL b O   1 
ATOM 1192 C CB  . VAL B 2 121 ? -14.86500 -7.45736  -29.18550 1.000 379.76212 ? 121 VAL b CB  1 
ATOM 1193 C CG1 . VAL B 2 121 ? -15.95400 -8.41736  -28.74050 1.000 379.76212 ? 121 VAL b CG1 1 
ATOM 1194 C CG2 . VAL B 2 121 ? -15.00200 -7.13436  -30.67050 1.000 379.76212 ? 121 VAL b CG2 1 
ATOM 1195 N N   . VAL B 2 122 ? -16.04100 -5.97736  -26.20750 1.000 203.81812 ? 122 VAL b N   1 
ATOM 1196 C CA  . VAL B 2 122 ? -16.10100 -5.92936  -24.74850 1.000 203.81812 ? 122 VAL b CA  1 
ATOM 1197 C C   . VAL B 2 122 ? -16.42100 -7.31136  -24.18850 1.000 203.81812 ? 122 VAL b C   1 
ATOM 1198 O O   . VAL B 2 122 ? -17.24500 -8.04736  -24.74350 1.000 203.81812 ? 122 VAL b O   1 
ATOM 1199 C CB  . VAL B 2 122 ? -17.13300 -4.88936  -24.27950 1.000 203.81812 ? 122 VAL b CB  1 
ATOM 1200 C CG1 . VAL B 2 122 ? -16.42100 -3.65336  -23.73150 1.000 203.81812 ? 122 VAL b CG1 1 
ATOM 1201 C CG2 . VAL B 2 122 ? -18.11200 -4.52836  -25.40650 1.000 203.81812 ? 122 VAL b CG2 1 
ATOM 1202 N N   . THR B 2 123 ? -15.75300 -7.67036  -23.09050 1.000 263.09777 ? 123 THR b N   1 
ATOM 1203 C CA  . THR B 2 123 ? -15.96700 -8.93336  -22.39750 1.000 263.09777 ? 123 THR b CA  1 
ATOM 1204 C C   . THR B 2 123 ? -16.46900 -8.68236  -20.97750 1.000 263.09777 ? 123 THR b C   1 
ATOM 1205 O O   . THR B 2 123 ? -16.13700 -7.67036  -20.35250 1.000 263.09777 ? 123 THR b O   1 
ATOM 1206 C CB  . THR B 2 123 ? -14.67800 -9.77436  -22.36250 1.000 263.09777 ? 123 THR b CB  1 
ATOM 1207 O OG1 . THR B 2 123 ? -13.68100 -9.10236  -21.58250 1.000 263.09777 ? 123 THR b OG1 1 
ATOM 1208 C CG2 . THR B 2 123 ? -14.14300 -9.99536  -23.77350 1.000 263.09777 ? 123 THR b CG2 1 
ATOM 1209 N N   . ASN B 2 124 ? -17.28700 -9.62536  -20.47450 0.500 307.98700 ? 124 ASN b N   1 
ATOM 1210 C CA  . ASN B 2 124 ? -17.92300 -9.59036  -19.16350 0.500 307.98700 ? 124 ASN b CA  1 
ATOM 1211 C C   . ASN B 2 124 ? -16.90700 -9.84936  -18.04350 0.500 307.98700 ? 124 ASN b C   1 
ATOM 1212 O O   . ASN B 2 124 ? -15.79200 -10.30536 -18.31250 0.500 307.98700 ? 124 ASN b O   1 
ATOM 1213 C CB  . ASN B 2 124 ? -19.08800 -10.60136 -19.12450 0.500 307.98700 ? 124 ASN b CB  1 
ATOM 1214 C CG  . ASN B 2 124 ? -18.67200 -12.04836 -19.42750 0.500 307.98700 ? 124 ASN b CG  1 
ATOM 1215 O OD1 . ASN B 2 124 ? -17.71400 -12.58936 -18.87850 0.500 307.98700 ? 124 ASN b OD1 1 
ATOM 1216 N ND2 . ASN B 2 124 ? -19.42200 -12.68036 -20.32050 0.500 307.98700 ? 124 ASN b ND2 1 
ATOM 1217 N N   . PRO B 2 125 ? -17.24300 -9.51836  -16.78950 0.500 308.85972 ? 125 PRO b N   1 
ATOM 1218 C CA  . PRO B 2 125 ? -16.37600 -9.91736  -15.66350 0.500 308.85972 ? 125 PRO b CA  1 
ATOM 1219 C C   . PRO B 2 125 ? -16.26900 -11.43136 -15.52550 0.500 308.85972 ? 125 PRO b C   1 
ATOM 1220 O O   . PRO B 2 125 ? -17.24100 -12.11336 -15.18450 0.500 308.85972 ? 125 PRO b O   1 
ATOM 1221 C CB  . PRO B 2 125 ? -17.06100 -9.28636  -14.44550 0.500 308.85972 ? 125 PRO b CB  1 
ATOM 1222 C CG  . PRO B 2 125 ? -17.79400 -8.12036  -14.99850 0.500 308.85972 ? 125 PRO b CG  1 
ATOM 1223 C CD  . PRO B 2 125 ? -18.22300 -8.49036  -16.38150 0.500 308.85972 ? 125 PRO b CD  1 
ATOM 1224 N N   . LYS B 2 126 ? -15.05600 -11.94136 -15.75650 0.500 321.66797 ? 126 LYS b N   1 
ATOM 1225 C CA  . LYS B 2 126 ? -14.81400 -13.36636 -15.95750 0.500 321.66797 ? 126 LYS b CA  1 
ATOM 1226 C C   . LYS B 2 126 ? -13.40400 -13.64836 -15.45950 0.500 321.66797 ? 126 LYS b C   1 
ATOM 1227 O O   . LYS B 2 126 ? -12.48600 -12.87436 -15.74150 0.500 321.66797 ? 126 LYS b O   1 
ATOM 1228 C CB  . LYS B 2 126 ? -14.98100 -13.69036 -17.45650 0.500 321.66797 ? 126 LYS b CB  1 
ATOM 1229 C CG  . LYS B 2 126 ? -14.92500 -15.13636 -18.03350 0.500 321.66797 ? 126 LYS b CG  1 
ATOM 1230 C CD  . LYS B 2 126 ? -14.79400 -16.31336 -17.08650 0.500 321.66797 ? 126 LYS b CD  1 
ATOM 1231 C CE  . LYS B 2 126 ? -14.74100 -17.61536 -17.84650 0.500 321.66797 ? 126 LYS b CE  1 
ATOM 1232 N NZ  . LYS B 2 126 ? -13.54700 -18.40736 -17.46650 0.500 321.66797 ? 126 LYS b NZ  1 
ATOM 1233 N N   . GLU B 2 127 ? -13.22400 -14.73736 -14.72250 0.500 375.81279 ? 127 GLU b N   1 
ATOM 1234 C CA  . GLU B 2 127 ? -11.89000 -15.12836 -14.30650 0.500 375.81279 ? 127 GLU b CA  1 
ATOM 1235 C C   . GLU B 2 127 ? -11.45000 -16.36536 -15.08050 0.500 375.81279 ? 127 GLU b C   1 
ATOM 1236 O O   . GLU B 2 127 ? -10.41800 -16.35736 -15.74950 0.500 375.81279 ? 127 GLU b O   1 
ATOM 1237 C CB  . GLU B 2 127 ? -11.83200 -15.39436 -12.79650 0.500 375.81279 ? 127 GLU b CB  1 
ATOM 1238 C CG  . GLU B 2 127 ? -10.41500 -15.33936 -12.22050 0.500 375.81279 ? 127 GLU b CG  1 
ATOM 1239 C CD  . GLU B 2 127 ? -9.71200  -16.68736 -12.25650 0.500 375.81279 ? 127 GLU b CD  1 
ATOM 1240 O OE1 . GLU B 2 127 ? -10.41300 -17.71736 -12.31950 0.500 375.81279 ? 127 GLU b OE1 1 
ATOM 1241 O OE2 . GLU B 2 127 ? -8.46400  -16.72736 -12.21450 0.500 375.81279 ? 127 GLU b OE2 1 
ATOM 1242 O OXT . GLU B 2 127 ? -12.11800 -17.39936 -15.07250 0.500 375.81279 ? 127 GLU b OXT 1 
ATOM 1243 N N   . GLY C 2 1   ? 8.91700   -7.13636  45.32850  0.500 543.92541 ? 1   GLY A N   1 
ATOM 1244 C CA  . GLY C 2 1   ? 10.33000  -6.82336  45.22950  0.500 543.92541 ? 1   GLY A CA  1 
ATOM 1245 C C   . GLY C 2 1   ? 10.61500  -5.33436  45.25250  0.500 543.92541 ? 1   GLY A C   1 
ATOM 1246 O O   . GLY C 2 1   ? 10.37400  -4.67336  46.26550  0.500 543.92541 ? 1   GLY A O   1 
ATOM 1247 N N   . PRO C 2 2   ? 11.13300  -4.80136  44.14450  0.500 555.32871 ? 2   PRO A N   1 
ATOM 1248 C CA  . PRO C 2 2   ? 11.40800  -3.35936  44.07550  0.500 555.32871 ? 2   PRO A CA  1 
ATOM 1249 C C   . PRO C 2 2   ? 10.10200  -2.58536  43.99050  0.500 555.32871 ? 2   PRO A C   1 
ATOM 1250 O O   . PRO C 2 2   ? 9.48800   -2.49036  42.92650  0.500 555.32871 ? 2   PRO A O   1 
ATOM 1251 C CB  . PRO C 2 2   ? 12.24100  -3.21036  42.79550  0.500 555.32871 ? 2   PRO A CB  1 
ATOM 1252 C CG  . PRO C 2 2   ? 12.65800  -4.60736  42.41950  0.500 555.32871 ? 2   PRO A CG  1 
ATOM 1253 C CD  . PRO C 2 2   ? 11.56000  -5.49236  42.91650  0.500 555.32871 ? 2   PRO A CD  1 
ATOM 1254 N N   . THR C 2 3   ? 9.68200   -2.03936  45.12250  0.500 600.23041 ? 3   THR A N   1 
ATOM 1255 C CA  . THR C 2 3   ? 8.44700   -1.28436  45.18450  0.500 600.23041 ? 3   THR A CA  1 
ATOM 1256 C C   . THR C 2 3   ? 8.68100   0.10164   44.60750  0.500 600.23041 ? 3   THR A C   1 
ATOM 1257 O O   . THR C 2 3   ? 9.70700   0.73464   44.87150  0.500 600.23041 ? 3   THR A O   1 
ATOM 1258 C CB  . THR C 2 3   ? 7.94100   -1.18736  46.62350  0.500 600.23041 ? 3   THR A CB  1 
ATOM 1259 O OG1 . THR C 2 3   ? 8.81000   -0.33536  47.37850  0.500 600.23041 ? 3   THR A OG1 1 
ATOM 1260 C CG2 . THR C 2 3   ? 7.90900   -2.56636  47.26550  0.500 600.23041 ? 3   THR A CG2 1 
ATOM 1261 N N   . GLY C 2 4   ? 7.73200   0.55864   43.80350  0.500 547.53945 ? 4   GLY A N   1 
ATOM 1262 C CA  . GLY C 2 4   ? 7.85200   1.84964   43.16650  0.500 547.53945 ? 4   GLY A CA  1 
ATOM 1263 C C   . GLY C 2 4   ? 8.66300   1.78964   41.89250  0.500 547.53945 ? 4   GLY A C   1 
ATOM 1264 O O   . GLY C 2 4   ? 8.11500   1.93064   40.79750  0.500 547.53945 ? 4   GLY A O   1 
ATOM 1265 N N   . THR C 2 5   ? 9.96700   1.56064   42.01350  0.500 595.42572 ? 5   THR A N   1 
ATOM 1266 C CA  . THR C 2 5   ? 10.84200  1.62664   40.85750  0.500 595.42572 ? 5   THR A CA  1 
ATOM 1267 C C   . THR C 2 5   ? 11.85100  0.49164   40.91350  0.500 595.42572 ? 5   THR A C   1 
ATOM 1268 O O   . THR C 2 5   ? 12.52200  0.28164   41.92650  0.500 595.42572 ? 5   THR A O   1 
ATOM 1269 C CB  . THR C 2 5   ? 11.55900  2.98164   40.79250  0.500 595.42572 ? 5   THR A CB  1 
ATOM 1270 O OG1 . THR C 2 5   ? 10.58600  4.03364   40.80350  0.500 595.42572 ? 5   THR A OG1 1 
ATOM 1271 C CG2 . THR C 2 5   ? 12.39300  3.09364   39.52950  0.500 595.42572 ? 5   THR A CG2 1 
ATOM 1272 N N   . GLY C 2 6   ? 11.94800  -0.24036  39.81050  0.500 528.47755 ? 6   GLY A N   1 
ATOM 1273 C CA  . GLY C 2 6   ? 12.92300  -1.30136  39.70550  0.500 528.47755 ? 6   GLY A CA  1 
ATOM 1274 C C   . GLY C 2 6   ? 12.81000  -1.98336  38.35750  0.500 528.47755 ? 6   GLY A C   1 
ATOM 1275 O O   . GLY C 2 6   ? 11.94500  -1.65336  37.54150  0.500 528.47755 ? 6   GLY A O   1 
ATOM 1276 N N   . GLU C 2 7   ? 13.69000  -2.95536  38.15050  0.500 532.25210 ? 7   GLU A N   1 
ATOM 1277 C CA  . GLU C 2 7   ? 13.88300  -3.53336  36.82850  0.500 532.25210 ? 7   GLU A CA  1 
ATOM 1278 C C   . GLU C 2 7   ? 13.92100  -5.05536  36.93550  0.500 532.25210 ? 7   GLU A C   1 
ATOM 1279 O O   . GLU C 2 7   ? 14.85600  -5.72336  36.49050  0.500 532.25210 ? 7   GLU A O   1 
ATOM 1280 C CB  . GLU C 2 7   ? 15.14200  -2.95436  36.18750  0.500 532.25210 ? 7   GLU A CB  1 
ATOM 1281 C CG  . GLU C 2 7   ? 15.18700  -3.09536  34.68150  0.500 532.25210 ? 7   GLU A CG  1 
ATOM 1282 C CD  . GLU C 2 7   ? 16.23100  -2.22636  34.05050  0.500 532.25210 ? 7   GLU A CD  1 
ATOM 1283 O OE1 . GLU C 2 7   ? 17.33900  -2.72836  33.78150  0.500 532.25210 ? 7   GLU A OE1 1 
ATOM 1284 O OE2 . GLU C 2 7   ? 15.95000  -1.03436  33.82550  0.500 532.25210 ? 7   GLU A OE2 1 
ATOM 1285 N N   . SER C 2 8   ? 12.89600  -5.61536  37.57650  0.500 485.88871 ? 8   SER A N   1 
ATOM 1286 C CA  . SER C 2 8   ? 12.80100  -7.06436  37.71450  0.500 485.88871 ? 8   SER A CA  1 
ATOM 1287 C C   . SER C 2 8   ? 12.41700  -7.71336  36.39150  0.500 485.88871 ? 8   SER A C   1 
ATOM 1288 O O   . SER C 2 8   ? 13.01600  -8.71036  35.96650  0.500 485.88871 ? 8   SER A O   1 
ATOM 1289 C CB  . SER C 2 8   ? 11.78200  -7.41436  38.79750  0.500 485.88871 ? 8   SER A CB  1 
ATOM 1290 O OG  . SER C 2 8   ? 10.50800  -6.88436  38.46850  0.500 485.88871 ? 8   SER A OG  1 
ATOM 1291 N N   . LYS C 2 9   ? 11.42400  -7.14036  35.71450  0.500 525.83251 ? 9   LYS A N   1 
ATOM 1292 C CA  . LYS C 2 9   ? 10.87600  -7.68236  34.48050  0.500 525.83251 ? 9   LYS A CA  1 
ATOM 1293 C C   . LYS C 2 9   ? 11.57400  -7.11036  33.25850  0.500 525.83251 ? 9   LYS A C   1 
ATOM 1294 O O   . LYS C 2 9   ? 11.16900  -7.39936  32.12650  0.500 525.83251 ? 9   LYS A O   1 
ATOM 1295 C CB  . LYS C 2 9   ? 9.38000   -7.38336  34.40550  0.500 525.83251 ? 9   LYS A CB  1 
ATOM 1296 C CG  . LYS C 2 9   ? 9.08100   -5.89536  34.54350  0.500 525.83251 ? 9   LYS A CG  1 
ATOM 1297 C CD  . LYS C 2 9   ? 7.61100   -5.62036  34.78650  0.500 525.83251 ? 9   LYS A CD  1 
ATOM 1298 C CE  . LYS C 2 9   ? 7.36300   -4.13736  35.01150  0.500 525.83251 ? 9   LYS A CE  1 
ATOM 1299 N NZ  . LYS C 2 9   ? 5.95000   -3.87536  35.39650  0.500 525.83251 ? 9   LYS A NZ  1 
ATOM 1300 N N   . ARG C 2 10  ? 12.63000  -6.31936  33.48350  1.000 664.06880 ? 10  ARG A N   1 
ATOM 1301 C CA  . ARG C 2 10  ? 13.29900  -5.44936  32.52250  1.000 664.06880 ? 10  ARG A CA  1 
ATOM 1302 C C   . ARG C 2 10  ? 12.27900  -4.61736  31.75150  1.000 664.06880 ? 10  ARG A C   1 
ATOM 1303 O O   . ARG C 2 10  ? 12.01100  -4.91836  30.58350  1.000 664.06880 ? 10  ARG A O   1 
ATOM 1304 C CB  . ARG C 2 10  ? 14.17800  -6.25636  31.56250  1.000 664.06880 ? 10  ARG A CB  1 
ATOM 1305 C CG  . ARG C 2 10  ? 15.60800  -6.49236  32.03450  1.000 664.06880 ? 10  ARG A CG  1 
ATOM 1306 C CD  . ARG C 2 10  ? 16.45300  -5.23836  31.88150  1.000 664.06880 ? 10  ARG A CD  1 
ATOM 1307 N NE  . ARG C 2 10  ? 16.20700  -4.51736  30.63350  1.000 664.06880 ? 10  ARG A NE  1 
ATOM 1308 C CZ  . ARG C 2 10  ? 16.94200  -4.64336  29.53250  1.000 664.06880 ? 10  ARG A CZ  1 
ATOM 1309 N NH1 . ARG C 2 10  ? 17.99400  -5.44736  29.51750  1.000 664.06880 ? 10  ARG A NH1 1 
ATOM 1310 N NH2 . ARG C 2 10  ? 16.63700  -3.94436  28.44750  1.000 664.06880 ? 10  ARG A NH2 1 
ATOM 1311 N N   . PRO C 2 11  ? 11.64500  -3.60836  32.36050  1.000 581.47721 ? 11  PRO A N   1 
ATOM 1312 C CA  . PRO C 2 11  ? 10.69100  -2.80236  31.58850  1.000 581.47721 ? 11  PRO A CA  1 
ATOM 1313 C C   . PRO C 2 11  ? 11.33600  -1.93536  30.50950  1.000 581.47721 ? 11  PRO A C   1 
ATOM 1314 O O   . PRO C 2 11  ? 10.82400  -1.94236  29.38450  1.000 581.47721 ? 11  PRO A O   1 
ATOM 1315 C CB  . PRO C 2 11  ? 9.98500   -1.96036  32.66150  1.000 581.47721 ? 11  PRO A CB  1 
ATOM 1316 C CG  . PRO C 2 11  ? 10.92600  -1.92936  33.79050  1.000 581.47721 ? 11  PRO A CG  1 
ATOM 1317 C CD  . PRO C 2 11  ? 11.63500  -3.23336  33.78650  1.000 581.47721 ? 11  PRO A CD  1 
ATOM 1318 N N   . LEU C 2 12  ? 12.45300  -1.24436  30.77050  1.000 558.13421 ? 12  LEU A N   1 
ATOM 1319 C CA  . LEU C 2 12  ? 13.01900  -0.36036  29.74350  1.000 558.13421 ? 12  LEU A CA  1 
ATOM 1320 C C   . LEU C 2 12  ? 14.51300  -0.12236  29.96250  1.000 558.13421 ? 12  LEU A C   1 
ATOM 1321 O O   . LEU C 2 12  ? 14.89500  0.57264   30.90750  1.000 558.13421 ? 12  LEU A O   1 
ATOM 1322 C CB  . LEU C 2 12  ? 12.25000  0.95764   29.71850  1.000 558.13421 ? 12  LEU A CB  1 
ATOM 1323 C CG  . LEU C 2 12  ? 12.54000  2.02564   28.66950  1.000 558.13421 ? 12  LEU A CG  1 
ATOM 1324 C CD1 . LEU C 2 12  ? 12.41500  1.47164   27.27350  1.000 558.13421 ? 12  LEU A CD1 1 
ATOM 1325 C CD2 . LEU C 2 12  ? 11.50600  3.09964   28.85750  1.000 558.13421 ? 12  LEU A CD2 1 
ATOM 1326 N N   . MET C 2 13  ? 15.35100  -0.67536  29.07650  1.000 647.91333 ? 13  MET A N   1 
ATOM 1327 C CA  . MET C 2 13  ? 16.78400  -0.35436  29.04350  1.000 647.91333 ? 13  MET A CA  1 
ATOM 1328 C C   . MET C 2 13  ? 17.30600  -0.62936  27.63550  1.000 647.91333 ? 13  MET A C   1 
ATOM 1329 O O   . MET C 2 13  ? 17.51400  -1.79136  27.27350  1.000 647.91333 ? 13  MET A O   1 
ATOM 1330 C CB  . MET C 2 13  ? 17.56400  -1.15436  30.07250  1.000 647.91333 ? 13  MET A CB  1 
ATOM 1331 C CG  . MET C 2 13  ? 19.00900  -0.72136  30.19650  1.000 647.91333 ? 13  MET A CG  1 
ATOM 1332 S SD  . MET C 2 13  ? 20.11900  -2.11736  30.45150  1.000 647.91333 ? 13  MET A SD  1 
ATOM 1333 C CE  . MET C 2 13  ? 20.23300  -2.78536  28.79550  1.000 647.91333 ? 13  MET A CE  1 
ATOM 1334 N N   . VAL C 2 14  ? 17.53800  0.43164   26.85950  1.000 692.43772 ? 14  VAL A N   1 
ATOM 1335 C CA  . VAL C 2 14  ? 17.88200  0.27164   25.45350  1.000 692.43772 ? 14  VAL A CA  1 
ATOM 1336 C C   . VAL C 2 14  ? 18.54800  1.53964   24.92750  1.000 692.43772 ? 14  VAL A C   1 
ATOM 1337 O O   . VAL C 2 14  ? 18.48600  2.60264   25.55450  1.000 692.43772 ? 14  VAL A O   1 
ATOM 1338 C CB  . VAL C 2 14  ? 16.61500  -0.08136  24.64050  1.000 692.43772 ? 14  VAL A CB  1 
ATOM 1339 C CG1 . VAL C 2 14  ? 15.81700  1.16864   24.25150  1.000 692.43772 ? 14  VAL A CG1 1 
ATOM 1340 C CG2 . VAL C 2 14  ? 16.93700  -0.98736  23.49950  1.000 692.43772 ? 14  VAL A CG2 1 
ATOM 1341 N N   . LYS C 2 15  ? 19.21200  1.41664   23.77750  1.000 579.21401 ? 15  LYS A N   1 
ATOM 1342 C CA  . LYS C 2 15  ? 19.76100  2.55264   23.04450  1.000 579.21401 ? 15  LYS A CA  1 
ATOM 1343 C C   . LYS C 2 15  ? 18.78600  2.98264   21.95250  1.000 579.21401 ? 15  LYS A C   1 
ATOM 1344 O O   . LYS C 2 15  ? 18.30400  2.14964   21.17950  1.000 579.21401 ? 15  LYS A O   1 
ATOM 1345 C CB  . LYS C 2 15  ? 21.11700  2.20264   22.43350  1.000 579.21401 ? 15  LYS A CB  1 
ATOM 1346 C CG  . LYS C 2 15  ? 21.55000  3.12864   21.31350  1.000 579.21401 ? 15  LYS A CG  1 
ATOM 1347 C CD  . LYS C 2 15  ? 22.75000  2.58564   20.58350  1.000 579.21401 ? 15  LYS A CD  1 
ATOM 1348 C CE  . LYS C 2 15  ? 22.96200  3.33164   19.28750  1.000 579.21401 ? 15  LYS A CE  1 
ATOM 1349 N NZ  . LYS C 2 15  ? 23.17900  4.78664   19.52450  1.000 579.21401 ? 15  LYS A NZ  1 
ATOM 1350 N N   . VAL C 2 16  ? 18.49600  4.28664   21.89750  1.000 505.41792 ? 16  VAL A N   1 
ATOM 1351 C CA  . VAL C 2 16  ? 17.47700  4.85264   21.01850  1.000 505.41792 ? 16  VAL A CA  1 
ATOM 1352 C C   . VAL C 2 16  ? 18.15800  5.78564   20.01950  1.000 505.41792 ? 16  VAL A C   1 
ATOM 1353 O O   . VAL C 2 16  ? 19.23200  6.33164   20.30050  1.000 505.41792 ? 16  VAL A O   1 
ATOM 1354 C CB  . VAL C 2 16  ? 16.40700  5.59364   21.85650  1.000 505.41792 ? 16  VAL A CB  1 
ATOM 1355 C CG1 . VAL C 2 16  ? 15.16600  5.96164   21.03650  1.000 505.41792 ? 16  VAL A CG1 1 
ATOM 1356 C CG2 . VAL C 2 16  ? 15.99900  4.77264   23.07550  1.000 505.41792 ? 16  VAL A CG2 1 
ATOM 1357 N N   . LEU C 2 17  ? 17.57300  5.91864   18.82750  1.000 513.58041 ? 17  LEU A N   1 
ATOM 1358 C CA  . LEU C 2 17  ? 17.89000  6.99464   17.89650  1.000 513.58041 ? 17  LEU A CA  1 
ATOM 1359 C C   . LEU C 2 17  ? 16.64500  7.83764   17.62950  1.000 513.58041 ? 17  LEU A C   1 
ATOM 1360 O O   . LEU C 2 17  ? 15.51500  7.37364   17.80050  1.000 513.58041 ? 17  LEU A O   1 
ATOM 1361 C CB  . LEU C 2 17  ? 18.44300  6.45764   16.57250  1.000 513.58041 ? 17  LEU A CB  1 
ATOM 1362 C CG  . LEU C 2 17  ? 19.96400  6.35464   16.43450  1.000 513.58041 ? 17  LEU A CG  1 
ATOM 1363 C CD1 . LEU C 2 17  ? 20.61600  7.71364   16.60550  1.000 513.58041 ? 17  LEU A CD1 1 
ATOM 1364 C CD2 . LEU C 2 17  ? 20.55600  5.35564   17.39750  1.000 513.58041 ? 17  LEU A CD2 1 
ATOM 1365 N N   . ASP C 2 18  ? 16.86400  9.08664   17.21850  1.000 414.14865 ? 18  ASP A N   1 
ATOM 1366 C CA  . ASP C 2 18  ? 15.79900  10.04164  16.92250  1.000 414.14865 ? 18  ASP A CA  1 
ATOM 1367 C C   . ASP C 2 18  ? 15.68300  10.23264  15.41650  1.000 414.14865 ? 18  ASP A C   1 
ATOM 1368 O O   . ASP C 2 18  ? 16.68100  10.12964  14.69450  1.000 414.14865 ? 18  ASP A O   1 
ATOM 1369 C CB  . ASP C 2 18  ? 16.07300  11.38464  17.61150  1.000 414.14865 ? 18  ASP A CB  1 
ATOM 1370 C CG  . ASP C 2 18  ? 14.85600  12.30564  17.67550  1.000 414.14865 ? 18  ASP A CG  1 
ATOM 1371 O OD1 . ASP C 2 18  ? 14.23500  12.60164  16.63350  1.000 414.14865 ? 18  ASP A OD1 1 
ATOM 1372 O OD2 . ASP C 2 18  ? 14.55500  12.79064  18.78350  1.000 414.14865 ? 18  ASP A OD2 1 
ATOM 1373 N N   . ALA C 2 19  ? 14.46300  10.52264  14.95150  1.000 382.55162 ? 19  ALA A N   1 
ATOM 1374 C CA  . ALA C 2 19  ? 14.25700  10.80464  13.53450  1.000 382.55162 ? 19  ALA A CA  1 
ATOM 1375 C C   . ALA C 2 19  ? 14.75400  12.19064  13.15950  1.000 382.55162 ? 19  ALA A C   1 
ATOM 1376 O O   . ALA C 2 19  ? 15.39300  12.35664  12.11550  1.000 382.55162 ? 19  ALA A O   1 
ATOM 1377 C CB  . ALA C 2 19  ? 12.78000  10.67064  13.16150  1.000 382.55162 ? 19  ALA A CB  1 
ATOM 1378 N N   . VAL C 2 20  ? 14.46400  13.19564  13.97750  1.000 358.61472 ? 20  VAL A N   1 
ATOM 1379 C CA  . VAL C 2 20  ? 14.85400  14.55764  13.63650  1.000 358.61472 ? 20  VAL A CA  1 
ATOM 1380 C C   . VAL C 2 20  ? 16.04300  15.03364  14.46050  1.000 358.61472 ? 20  VAL A C   1 
ATOM 1381 O O   . VAL C 2 20  ? 16.67800  16.02964  14.11050  1.000 358.61472 ? 20  VAL A O   1 
ATOM 1382 C CB  . VAL C 2 20  ? 13.64600  15.49964  13.77450  1.000 358.61472 ? 20  VAL A CB  1 
ATOM 1383 C CG1 . VAL C 2 20  ? 12.64700  15.21064  12.67550  1.000 358.61472 ? 20  VAL A CG1 1 
ATOM 1384 C CG2 . VAL C 2 20  ? 12.99900  15.32064  15.12050  1.000 358.61472 ? 20  VAL A CG2 1 
ATOM 1385 N N   . ARG C 2 21  ? 16.36600  14.36664  15.56650  1.000 435.01370 ? 21  ARG A N   1 
ATOM 1386 C CA  . ARG C 2 21  ? 17.53500  14.75964  16.34650  1.000 435.01370 ? 21  ARG A CA  1 
ATOM 1387 C C   . ARG C 2 21  ? 18.72700  13.82664  16.17750  1.000 435.01370 ? 21  ARG A C   1 
ATOM 1388 O O   . ARG C 2 21  ? 19.85900  14.24564  16.43550  1.000 435.01370 ? 21  ARG A O   1 
ATOM 1389 C CB  . ARG C 2 21  ? 17.18200  14.85764  17.83250  1.000 435.01370 ? 21  ARG A CB  1 
ATOM 1390 C CG  . ARG C 2 21  ? 16.03400  15.80064  18.12850  1.000 435.01370 ? 21  ARG A CG  1 
ATOM 1391 C CD  . ARG C 2 21  ? 15.74000  15.79764  19.60550  1.000 435.01370 ? 21  ARG A CD  1 
ATOM 1392 N NE  . ARG C 2 21  ? 15.68900  14.43064  20.10950  1.000 435.01370 ? 21  ARG A NE  1 
ATOM 1393 C CZ  . ARG C 2 21  ? 16.11200  14.06764  21.31150  1.000 435.01370 ? 21  ARG A CZ  1 
ATOM 1394 N NH1 . ARG C 2 21  ? 16.62100  14.97364  22.13050  1.000 435.01370 ? 21  ARG A NH1 1 
ATOM 1395 N NH2 . ARG C 2 21  ? 16.03300  12.80064  21.68950  1.000 435.01370 ? 21  ARG A NH2 1 
ATOM 1396 N N   . GLY C 2 22  ? 18.50700  12.58164  15.75750  1.000 382.80659 ? 22  GLY A N   1 
ATOM 1397 C CA  . GLY C 2 22  ? 19.58800  11.61964  15.63350  1.000 382.80659 ? 22  GLY A CA  1 
ATOM 1398 C C   . GLY C 2 22  ? 20.23700  11.24164  16.94550  1.000 382.80659 ? 22  GLY A C   1 
ATOM 1399 O O   . GLY C 2 22  ? 21.43900  10.96664  16.98050  1.000 382.80659 ? 22  GLY A O   1 
ATOM 1400 N N   . SER C 2 23  ? 19.47600  11.22964  18.02550  1.000 347.83505 ? 23  SER A N   1 
ATOM 1401 C CA  . SER C 2 23  ? 20.02800  11.03764  19.35550  1.000 347.83505 ? 23  SER A CA  1 
ATOM 1402 C C   . SER C 2 23  ? 19.10400  10.10764  20.13050  1.000 347.83505 ? 23  SER A C   1 
ATOM 1403 O O   . SER C 2 23  ? 18.00600  9.80564   19.65250  1.000 347.83505 ? 23  SER A O   1 
ATOM 1404 C CB  . SER C 2 23  ? 20.18200  12.38964  20.05750  1.000 347.83505 ? 23  SER A CB  1 
ATOM 1405 O OG  . SER C 2 23  ? 18.95600  12.81164  20.62950  1.000 347.83505 ? 23  SER A OG  1 
ATOM 1406 N N   . PRO C 2 24  ? 19.50700  9.60164   21.29550  1.000 404.60246 ? 24  PRO A N   1 
ATOM 1407 C CA  . PRO C 2 24  ? 18.54100  8.92664   22.16850  1.000 404.60246 ? 24  PRO A CA  1 
ATOM 1408 C C   . PRO C 2 24  ? 17.44400  9.86564   22.65250  1.000 404.60246 ? 24  PRO A C   1 
ATOM 1409 O O   . PRO C 2 24  ? 17.55800  11.09164  22.59150  1.000 404.60246 ? 24  PRO A O   1 
ATOM 1410 C CB  . PRO C 2 24  ? 19.40600  8.42564   23.32650  1.000 404.60246 ? 24  PRO A CB  1 
ATOM 1411 C CG  . PRO C 2 24  ? 20.71900  8.16364   22.69050  1.000 404.60246 ? 24  PRO A CG  1 
ATOM 1412 C CD  . PRO C 2 24  ? 20.89200  9.21564   21.62450  1.000 404.60246 ? 24  PRO A CD  1 
ATOM 1413 N N   . ALA C 2 25  ? 16.35300  9.25964   23.11750  1.000 534.25404 ? 25  ALA A N   1 
ATOM 1414 C CA  . ALA C 2 25  ? 15.15100  10.00764  23.46450  1.000 534.25404 ? 25  ALA A CA  1 
ATOM 1415 C C   . ALA C 2 25  ? 15.38800  10.78864  24.74850  1.000 534.25404 ? 25  ALA A C   1 
ATOM 1416 O O   . ALA C 2 25  ? 15.18300  10.27664  25.84850  1.000 534.25404 ? 25  ALA A O   1 
ATOM 1417 C CB  . ALA C 2 25  ? 13.96900  9.05464   23.60350  1.000 534.25404 ? 25  ALA A CB  1 
ATOM 1418 N N   . ILE C 2 26  ? 15.79800  12.03964  24.61350  1.000 517.14600 ? 26  ILE A N   1 
ATOM 1419 C CA  . ILE C 2 26  ? 16.26200  12.83464  25.73950  1.000 517.14600 ? 26  ILE A CA  1 
ATOM 1420 C C   . ILE C 2 26  ? 15.04900  13.42864  26.43950  1.000 517.14600 ? 26  ILE A C   1 
ATOM 1421 O O   . ILE C 2 26  ? 14.35500  14.27864  25.86550  1.000 517.14600 ? 26  ILE A O   1 
ATOM 1422 C CB  . ILE C 2 26  ? 17.23900  13.92864  25.28250  1.000 517.14600 ? 26  ILE A CB  1 
ATOM 1423 C CG1 . ILE C 2 26  ? 18.52900  13.30064  24.75350  1.000 517.14600 ? 26  ILE A CG1 1 
ATOM 1424 C CG2 . ILE C 2 26  ? 17.54400  14.88764  26.41150  1.000 517.14600 ? 26  ILE A CG2 1 
ATOM 1425 C CD1 . ILE C 2 26  ? 19.41900  14.25964  23.99450  1.000 517.14600 ? 26  ILE A CD1 1 
ATOM 1426 N N   . ASN C 2 27  ? 14.78600  12.94164  27.66250  1.000 504.94647 ? 27  ASN A N   1 
ATOM 1427 C CA  . ASN C 2 27  ? 13.81500  13.51864  28.60450  1.000 504.94647 ? 27  ASN A CA  1 
ATOM 1428 C C   . ASN C 2 27  ? 12.40600  13.57864  28.02250  1.000 504.94647 ? 27  ASN A C   1 
ATOM 1429 O O   . ASN C 2 27  ? 11.76300  14.63064  28.00350  1.000 504.94647 ? 27  ASN A O   1 
ATOM 1430 C CB  . ASN C 2 27  ? 14.25800  14.90364  29.07650  1.000 504.94647 ? 27  ASN A CB  1 
ATOM 1431 C CG  . ASN C 2 27  ? 13.72400  15.24164  30.45250  1.000 504.94647 ? 27  ASN A CG  1 
ATOM 1432 O OD1 . ASN C 2 27  ? 13.18000  14.38764  31.14350  1.000 504.94647 ? 27  ASN A OD1 1 
ATOM 1433 N ND2 . ASN C 2 27  ? 13.85400  16.50064  30.84650  1.000 504.94647 ? 27  ASN A ND2 1 
ATOM 1434 N N   . VAL C 2 28  ? 11.92900  12.44064  27.53150  1.000 563.34217 ? 28  VAL A N   1 
ATOM 1435 C CA  . VAL C 2 28  ? 10.64900  12.44164  26.84150  1.000 563.34217 ? 28  VAL A CA  1 
ATOM 1436 C C   . VAL C 2 28  ? 9.52900   12.51064  27.86250  1.000 563.34217 ? 28  VAL A C   1 
ATOM 1437 O O   . VAL C 2 28  ? 9.38400   11.62464  28.71150  1.000 563.34217 ? 28  VAL A O   1 
ATOM 1438 C CB  . VAL C 2 28  ? 10.51000  11.22364  25.92750  1.000 563.34217 ? 28  VAL A CB  1 
ATOM 1439 C CG1 . VAL C 2 28  ? 9.05300   11.02964  25.52650  1.000 563.34217 ? 28  VAL A CG1 1 
ATOM 1440 C CG2 . VAL C 2 28  ? 11.35900  11.43764  24.71350  1.000 563.34217 ? 28  VAL A CG2 1 
ATOM 1441 N N   . ALA C 2 29  ? 8.75000   13.58264  27.80250  1.000 578.29731 ? 29  ALA A N   1 
ATOM 1442 C CA  . ALA C 2 29  ? 7.53100   13.65164  28.58550  1.000 578.29731 ? 29  ALA A CA  1 
ATOM 1443 C C   . ALA C 2 29  ? 6.52200   12.65964  28.02250  1.000 578.29731 ? 29  ALA A C   1 
ATOM 1444 O O   . ALA C 2 29  ? 6.22000   12.67664  26.82450  1.000 578.29731 ? 29  ALA A O   1 
ATOM 1445 C CB  . ALA C 2 29  ? 6.98000   15.07464  28.58150  1.000 578.29731 ? 29  ALA A CB  1 
ATOM 1446 N N   . VAL C 2 30  ? 5.98600   11.80864  28.89450  1.000 533.84995 ? 30  VAL A N   1 
ATOM 1447 C CA  . VAL C 2 30  ? 5.35900   10.54964  28.50950  1.000 533.84995 ? 30  VAL A CA  1 
ATOM 1448 C C   . VAL C 2 30  ? 3.85900   10.63764  28.75450  1.000 533.84995 ? 30  VAL A C   1 
ATOM 1449 O O   . VAL C 2 30  ? 3.42700   11.01964  29.84650  1.000 533.84995 ? 30  VAL A O   1 
ATOM 1450 C CB  . VAL C 2 30  ? 5.97700   9.37464   29.29450  1.000 533.84995 ? 30  VAL A CB  1 
ATOM 1451 C CG1 . VAL C 2 30  ? 5.09300   8.13364   29.26550  1.000 533.84995 ? 30  VAL A CG1 1 
ATOM 1452 C CG2 . VAL C 2 30  ? 7.33700   9.05364   28.75050  1.000 533.84995 ? 30  VAL A CG2 1 
ATOM 1453 N N   . HIS C 2 31  ? 3.07200   10.29864  27.73750  1.000 477.04649 ? 31  HIS A N   1 
ATOM 1454 C CA  . HIS C 2 31  ? 1.65200   10.01264  27.89450  1.000 477.04649 ? 31  HIS A CA  1 
ATOM 1455 C C   . HIS C 2 31  ? 1.39600   8.58164   27.44550  1.000 477.04649 ? 31  HIS A C   1 
ATOM 1456 O O   . HIS C 2 31  ? 1.64500   8.23464   26.28550  1.000 477.04649 ? 31  HIS A O   1 
ATOM 1457 C CB  . HIS C 2 31  ? 0.79400   10.99464  27.09550  1.000 477.04649 ? 31  HIS A CB  1 
ATOM 1458 C CG  . HIS C 2 31  ? 0.28700   12.15164  27.89950  1.000 477.04649 ? 31  HIS A CG  1 
ATOM 1459 N ND1 . HIS C 2 31  ? -1.01600  12.23864  28.34150  1.000 477.04649 ? 31  HIS A ND1 1 
ATOM 1460 C CD2 . HIS C 2 31  ? 0.91100   13.26264  28.35750  1.000 477.04649 ? 31  HIS A CD2 1 
ATOM 1461 C CE1 . HIS C 2 31  ? -1.17500  13.35864  29.02350  1.000 477.04649 ? 31  HIS A CE1 1 
ATOM 1462 N NE2 . HIS C 2 31  ? -0.02000  13.99864  29.04850  1.000 477.04649 ? 31  HIS A NE2 1 
ATOM 1463 N N   . VAL C 2 32  ? 0.90500   7.75964   28.36350  1.000 630.76572 ? 32  VAL A N   1 
ATOM 1464 C CA  . VAL C 2 32  ? 0.72100   6.33164   28.13050  1.000 630.76572 ? 32  VAL A CA  1 
ATOM 1465 C C   . VAL C 2 32  ? -0.66300  6.10264   27.54150  1.000 630.76572 ? 32  VAL A C   1 
ATOM 1466 O O   . VAL C 2 32  ? -1.66800  6.56364   28.08950  1.000 630.76572 ? 32  VAL A O   1 
ATOM 1467 C CB  . VAL C 2 32  ? 0.91400   5.54564   29.44050  1.000 630.76572 ? 32  VAL A CB  1 
ATOM 1468 C CG1 . VAL C 2 32  ? 0.49300   4.09064   29.27550  1.000 630.76572 ? 32  VAL A CG1 1 
ATOM 1469 C CG2 . VAL C 2 32  ? 2.35100   5.66264   29.92850  1.000 630.76572 ? 32  VAL A CG2 1 
ATOM 1470 N N   . PHE C 2 33  ? -0.72200  5.38364   26.42450  1.000 620.75192 ? 33  PHE A N   1 
ATOM 1471 C CA  . PHE C 2 33  ? -1.97500  5.15564   25.72450  1.000 620.75192 ? 33  PHE A CA  1 
ATOM 1472 C C   . PHE C 2 33  ? -2.28200  3.66364   25.67850  1.000 620.75192 ? 33  PHE A C   1 
ATOM 1473 O O   . PHE C 2 33  ? -1.38000  2.82164   25.68350  1.000 620.75192 ? 33  PHE A O   1 
ATOM 1474 C CB  . PHE C 2 33  ? -1.93000  5.76564   24.31850  1.000 620.75192 ? 33  PHE A CB  1 
ATOM 1475 C CG  . PHE C 2 33  ? -2.16400  7.25364   24.29650  1.000 620.75192 ? 33  PHE A CG  1 
ATOM 1476 C CD1 . PHE C 2 33  ? -1.14600  8.13664   24.61950  1.000 620.75192 ? 33  PHE A CD1 1 
ATOM 1477 C CD2 . PHE C 2 33  ? -3.40300  7.76764   23.95950  1.000 620.75192 ? 33  PHE A CD2 1 
ATOM 1478 C CE1 . PHE C 2 33  ? -1.36300  9.50264   24.60750  1.000 620.75192 ? 33  PHE A CE1 1 
ATOM 1479 C CE2 . PHE C 2 33  ? -3.62400  9.13064   23.93750  1.000 620.75192 ? 33  PHE A CE2 1 
ATOM 1480 C CZ  . PHE C 2 33  ? -2.59900  9.99664   24.26250  1.000 620.75192 ? 33  PHE A CZ  1 
ATOM 1481 N N   . ARG C 2 34  ? -3.57700  3.34564   25.62950  1.000 465.95031 ? 34  ARG A N   1 
ATOM 1482 C CA  . ARG C 2 34  ? -4.06600  1.97764   25.77150  1.000 465.95031 ? 34  ARG A CA  1 
ATOM 1483 C C   . ARG C 2 34  ? -4.93900  1.60664   24.58250  1.000 465.95031 ? 34  ARG A C   1 
ATOM 1484 O O   . ARG C 2 34  ? -5.93800  2.27764   24.30950  1.000 465.95031 ? 34  ARG A O   1 
ATOM 1485 C CB  . ARG C 2 34  ? -4.86300  1.80664   27.07250  1.000 465.95031 ? 34  ARG A CB  1 
ATOM 1486 C CG  . ARG C 2 34  ? -5.68600  0.53164   27.11850  1.000 465.95031 ? 34  ARG A CG  1 
ATOM 1487 C CD  . ARG C 2 34  ? -6.59200  0.45664   28.32950  1.000 465.95031 ? 34  ARG A CD  1 
ATOM 1488 N NE  . ARG C 2 34  ? -7.27100  -0.83336  28.38050  1.000 465.95031 ? 34  ARG A NE  1 
ATOM 1489 C CZ  . ARG C 2 34  ? -8.41600  -1.09536  27.76350  1.000 465.95031 ? 34  ARG A CZ  1 
ATOM 1490 N NH1 . ARG C 2 34  ? -9.01600  -0.15436  27.04850  1.000 465.95031 ? 34  ARG A NH1 1 
ATOM 1491 N NH2 . ARG C 2 34  ? -8.96200  -2.29836  27.85850  1.000 465.95031 ? 34  ARG A NH2 1 
ATOM 1492 N N   . LYS C 2 35  ? -4.57800  0.52064   23.90250  1.000 439.89070 ? 35  LYS A N   1 
ATOM 1493 C CA  . LYS C 2 35  ? -5.29400  0.07064   22.71350  1.000 439.89070 ? 35  LYS A CA  1 
ATOM 1494 C C   . LYS C 2 35  ? -6.64700  -0.51836  23.10350  1.000 439.89070 ? 35  LYS A C   1 
ATOM 1495 O O   . LYS C 2 35  ? -6.72300  -1.38936  23.97650  1.000 439.89070 ? 35  LYS A O   1 
ATOM 1496 C CB  . LYS C 2 35  ? -4.45200  -0.95836  21.96350  1.000 439.89070 ? 35  LYS A CB  1 
ATOM 1497 C CG  . LYS C 2 35  ? -5.09100  -1.53636  20.71150  1.000 439.89070 ? 35  LYS A CG  1 
ATOM 1498 C CD  . LYS C 2 35  ? -5.21100  -0.50036  19.60950  1.000 439.89070 ? 35  LYS A CD  1 
ATOM 1499 C CE  . LYS C 2 35  ? -5.57800  -1.15136  18.28950  1.000 439.89070 ? 35  LYS A CE  1 
ATOM 1500 N NZ  . LYS C 2 35  ? -4.46600  -2.00836  17.78650  1.000 439.89070 ? 35  LYS A NZ  1 
ATOM 1501 N N   . ALA C 2 36  ? -7.71100  -0.03736  22.46350  1.000 486.54960 ? 36  ALA A N   1 
ATOM 1502 C CA  . ALA C 2 36  ? -9.05000  -0.56436  22.67850  1.000 486.54960 ? 36  ALA A CA  1 
ATOM 1503 C C   . ALA C 2 36  ? -9.46900  -1.40536  21.47250  1.000 486.54960 ? 36  ALA A C   1 
ATOM 1504 O O   . ALA C 2 36  ? -8.70400  -1.59936  20.52450  1.000 486.54960 ? 36  ALA A O   1 
ATOM 1505 C CB  . ALA C 2 36  ? -10.03000 0.57464   22.95150  1.000 486.54960 ? 36  ALA A CB  1 
ATOM 1506 N N   . ALA C 2 37  ? -10.70700 -1.90736  21.49150  1.000 537.65148 ? 37  ALA A N   1 
ATOM 1507 C CA  . ALA C 2 37  ? -11.18300 -2.75736  20.40750  1.000 537.65148 ? 37  ALA A CA  1 
ATOM 1508 C C   . ALA C 2 37  ? -11.60400 -1.95536  19.18650  1.000 537.65148 ? 37  ALA A C   1 
ATOM 1509 O O   . ALA C 2 37  ? -11.55700 -2.47836  18.06750  1.000 537.65148 ? 37  ALA A O   1 
ATOM 1510 C CB  . ALA C 2 37  ? -12.34700 -3.62236  20.88750  1.000 537.65148 ? 37  ALA A CB  1 
ATOM 1511 N N   . ASP C 2 38  ? -11.99200 -0.69736  19.36850  1.000 592.78651 ? 38  ASP A N   1 
ATOM 1512 C CA  . ASP C 2 38  ? -12.32700 0.19664   18.26850  1.000 592.78651 ? 38  ASP A CA  1 
ATOM 1513 C C   . ASP C 2 38  ? -11.13100 1.06864   17.89850  1.000 592.78651 ? 38  ASP A C   1 
ATOM 1514 O O   . ASP C 2 38  ? -11.28200 2.19264   17.41650  1.000 592.78651 ? 38  ASP A O   1 
ATOM 1515 C CB  . ASP C 2 38  ? -13.53900 1.05164   18.62250  1.000 592.78651 ? 38  ASP A CB  1 
ATOM 1516 C CG  . ASP C 2 38  ? -13.41000 1.70164   19.98350  1.000 592.78651 ? 38  ASP A CG  1 
ATOM 1517 O OD1 . ASP C 2 38  ? -12.45000 1.37764   20.71550  1.000 592.78651 ? 38  ASP A OD1 1 
ATOM 1518 O OD2 . ASP C 2 38  ? -14.27100 2.53864   20.32250  1.000 592.78651 ? 38  ASP A OD2 1 
ATOM 1519 N N   . ASP C 2 39  ? -9.93400  0.55364   18.19450  1.000 599.45145 ? 39  ASP A N   1 
ATOM 1520 C CA  . ASP C 2 39  ? -8.61100  0.96964   17.72550  1.000 599.45145 ? 39  ASP A CA  1 
ATOM 1521 C C   . ASP C 2 39  ? -8.09500  2.26364   18.34350  1.000 599.45145 ? 39  ASP A C   1 
ATOM 1522 O O   . ASP C 2 39  ? -6.91000  2.57064   18.18650  1.000 599.45145 ? 39  ASP A O   1 
ATOM 1523 C CB  . ASP C 2 39  ? -8.56300  1.10564   16.19850  1.000 599.45145 ? 39  ASP A CB  1 
ATOM 1524 C CG  . ASP C 2 39  ? -8.89300  -0.18936  15.49350  1.000 599.45145 ? 39  ASP A CG  1 
ATOM 1525 O OD1 . ASP C 2 39  ? -8.35100  -1.23936  15.89350  1.000 599.45145 ? 39  ASP A OD1 1 
ATOM 1526 O OD2 . ASP C 2 39  ? -9.70700  -0.15536  14.54650  1.000 599.45145 ? 39  ASP A OD2 1 
ATOM 1527 N N   . THR C 2 40  ? -8.91100  2.99664   19.09150  1.000 629.96242 ? 40  THR A N   1 
ATOM 1528 C CA  . THR C 2 40  ? -8.51200  4.28764   19.63050  1.000 629.96242 ? 40  THR A CA  1 
ATOM 1529 C C   . THR C 2 40  ? -7.89200  4.11464   21.01050  1.000 629.96242 ? 40  THR A C   1 
ATOM 1530 O O   . THR C 2 40  ? -8.08900  3.09664   21.67650  1.000 629.96242 ? 40  THR A O   1 
ATOM 1531 C CB  . THR C 2 40  ? -9.71000  5.25664   19.64650  1.000 629.96242 ? 40  THR A CB  1 
ATOM 1532 O OG1 . THR C 2 40  ? -9.36100  6.45564   18.93950  1.000 629.96242 ? 40  THR A OG1 1 
ATOM 1533 C CG2 . THR C 2 40  ? -10.28900 5.56564   21.06650  1.000 629.96242 ? 40  THR A CG2 1 
ATOM 1534 N N   . TRP C 2 41  ? -7.09800  5.10364   21.41150  1.000 565.48561 ? 41  TRP A N   1 
ATOM 1535 C CA  . TRP C 2 41  ? -6.28200  5.01664   22.60950  1.000 565.48561 ? 41  TRP A CA  1 
ATOM 1536 C C   . TRP C 2 41  ? -6.56400  6.23964   23.47250  1.000 565.48561 ? 41  TRP A C   1 
ATOM 1537 O O   . TRP C 2 41  ? -6.88200  7.31264   22.94950  1.000 565.48561 ? 41  TRP A O   1 
ATOM 1538 C CB  . TRP C 2 41  ? -4.79200  4.95064   22.27950  1.000 565.48561 ? 41  TRP A CB  1 
ATOM 1539 C CG  . TRP C 2 41  ? -4.32100  4.03564   21.17050  1.000 565.48561 ? 41  TRP A CG  1 
ATOM 1540 C CD1 . TRP C 2 41  ? -4.71700  4.02564   19.86050  1.000 565.48561 ? 41  TRP A CD1 1 
ATOM 1541 C CD2 . TRP C 2 41  ? -3.28000  3.06264   21.27150  1.000 565.48561 ? 41  TRP A CD2 1 
ATOM 1542 N NE1 . TRP C 2 41  ? -4.02900  3.07364   19.15850  1.000 565.48561 ? 41  TRP A NE1 1 
ATOM 1543 C CE2 . TRP C 2 41  ? -3.13500  2.46964   20.00150  1.000 565.48561 ? 41  TRP A CE2 1 
ATOM 1544 C CE3 . TRP C 2 41  ? -2.47200  2.61764   22.31950  1.000 565.48561 ? 41  TRP A CE3 1 
ATOM 1545 C CZ2 . TRP C 2 41  ? -2.21600  1.46064   19.75250  1.000 565.48561 ? 41  TRP A CZ2 1 
ATOM 1546 C CZ3 . TRP C 2 41  ? -1.56100  1.61164   22.07150  1.000 565.48561 ? 41  TRP A CZ3 1 
ATOM 1547 C CH2 . TRP C 2 41  ? -1.44100  1.04264   20.79750  1.000 565.48561 ? 41  TRP A CH2 1 
ATOM 1548 N N   . GLU C 2 42  ? -6.45000  6.07564   24.78550  1.000 637.25539 ? 42  GLU A N   1 
ATOM 1549 C CA  . GLU C 2 42  ? -6.70800  7.10064   25.78750  1.000 637.25539 ? 42  GLU A CA  1 
ATOM 1550 C C   . GLU C 2 42  ? -5.47200  7.33664   26.64950  1.000 637.25539 ? 42  GLU A C   1 
ATOM 1551 O O   . GLU C 2 42  ? -4.73200  6.39164   26.93250  1.000 637.25539 ? 42  GLU A O   1 
ATOM 1552 C CB  . GLU C 2 42  ? -7.87700  6.68164   26.67950  1.000 637.25539 ? 42  GLU A CB  1 
ATOM 1553 C CG  . GLU C 2 42  ? -9.24000  6.87264   26.04150  1.000 637.25539 ? 42  GLU A CG  1 
ATOM 1554 C CD  . GLU C 2 42  ? -10.37100 6.82964   27.05050  1.000 637.25539 ? 42  GLU A CD  1 
ATOM 1555 O OE1 . GLU C 2 42  ? -10.10000 6.56864   28.24050  1.000 637.25539 ? 42  GLU A OE1 1 
ATOM 1556 O OE2 . GLU C 2 42  ? -11.53200 7.05764   26.65450  1.000 637.25539 ? 42  GLU A OE2 1 
ATOM 1557 N N   . PRO C 2 43  ? -5.21900  8.57164   27.08850  1.000 633.94754 ? 43  PRO A N   1 
ATOM 1558 C CA  . PRO C 2 43  ? -4.03000  8.83364   27.91650  1.000 633.94754 ? 43  PRO A CA  1 
ATOM 1559 C C   . PRO C 2 43  ? -4.16700  8.25564   29.32050  1.000 633.94754 ? 43  PRO A C   1 
ATOM 1560 O O   . PRO C 2 43  ? -5.27600  8.04164   29.81650  1.000 633.94754 ? 43  PRO A O   1 
ATOM 1561 C CB  . PRO C 2 43  ? -3.95000  10.36564  27.95550  1.000 633.94754 ? 43  PRO A CB  1 
ATOM 1562 C CG  . PRO C 2 43  ? -4.87300  10.84864  26.88250  1.000 633.94754 ? 43  PRO A CG  1 
ATOM 1563 C CD  . PRO C 2 43  ? -5.93200  9.81164   26.74250  1.000 633.94754 ? 43  PRO A CD  1 
ATOM 1564 N N   . PHE C 2 44  ? -3.02000  7.99264   29.95850  1.000 629.62142 ? 44  PHE A N   1 
ATOM 1565 C CA  . PHE C 2 44  ? -2.98200  7.43064   31.31050  1.000 629.62142 ? 44  PHE A CA  1 
ATOM 1566 C C   . PHE C 2 44  ? -2.35600  8.35564   32.32950  1.000 629.62142 ? 44  PHE A C   1 
ATOM 1567 O O   . PHE C 2 44  ? -3.00500  8.69764   33.32650  1.000 629.62142 ? 44  PHE A O   1 
ATOM 1568 C CB  . PHE C 2 44  ? -2.25900  6.06864   31.27850  1.000 629.62142 ? 44  PHE A CB  1 
ATOM 1569 C CG  . PHE C 2 44  ? -1.77600  5.59564   32.62650  1.000 629.62142 ? 44  PHE A CG  1 
ATOM 1570 C CD1 . PHE C 2 44  ? -2.67000  5.29964   33.65150  1.000 629.62142 ? 44  PHE A CD1 1 
ATOM 1571 C CD2 . PHE C 2 44  ? -0.42000  5.42964   32.85850  1.000 629.62142 ? 44  PHE A CD2 1 
ATOM 1572 C CE1 . PHE C 2 44  ? -2.21200  4.86864   34.88450  1.000 629.62142 ? 44  PHE A CE1 1 
ATOM 1573 C CE2 . PHE C 2 44  ? 0.04300   4.99964   34.08750  1.000 629.62142 ? 44  PHE A CE2 1 
ATOM 1574 C CZ  . PHE C 2 44  ? -0.85400  4.71764   35.10150  1.000 629.62142 ? 44  PHE A CZ  1 
ATOM 1575 N N   . ALA C 2 45  ? -1.10600  8.79664   32.13950  1.000 621.36881 ? 45  ALA A N   1 
ATOM 1576 C CA  . ALA C 2 45  ? -0.40800  9.57564   33.16250  1.000 621.36881 ? 45  ALA A CA  1 
ATOM 1577 C C   . ALA C 2 45  ? 0.69100   10.40664  32.50450  1.000 621.36881 ? 45  ALA A C   1 
ATOM 1578 O O   . ALA C 2 45  ? 0.75200   10.53064  31.27750  1.000 621.36881 ? 45  ALA A O   1 
ATOM 1579 C CB  . ALA C 2 45  ? 0.15400   8.66664   34.26450  1.000 621.36881 ? 45  ALA A CB  1 
ATOM 1580 N N   . SER C 2 46  ? 1.56600   10.97764  33.33350  1.000 529.01525 ? 46  SER A N   1 
ATOM 1581 C CA  . SER C 2 46  ? 2.57200   11.91664  32.86050  1.000 529.01525 ? 46  SER A CA  1 
ATOM 1582 C C   . SER C 2 46  ? 3.90500   11.62664  33.53750  1.000 529.01525 ? 46  SER A C   1 
ATOM 1583 O O   . SER C 2 46  ? 3.96300   11.04064  34.62150  1.000 529.01525 ? 46  SER A O   1 
ATOM 1584 C CB  . SER C 2 46  ? 2.14800   13.37064  33.11150  1.000 529.01525 ? 46  SER A CB  1 
ATOM 1585 O OG  . SER C 2 46  ? 0.86500   13.63064  32.56350  1.000 529.01525 ? 46  SER A OG  1 
ATOM 1586 N N   . GLY C 2 47  ? 4.97500   12.05964  32.88050  1.000 613.18901 ? 47  GLY A N   1 
ATOM 1587 C CA  . GLY C 2 47  ? 6.32100   11.80164  33.35650  1.000 613.18901 ? 47  GLY A CA  1 
ATOM 1588 C C   . GLY C 2 47  ? 7.31900   12.55264  32.50250  1.000 613.18901 ? 47  GLY A C   1 
ATOM 1589 O O   . GLY C 2 47  ? 6.96000   13.49064  31.78850  1.000 613.18901 ? 47  GLY A O   1 
ATOM 1590 N N   . LYS C 2 48  ? 8.58600   12.14364  32.60950  1.000 630.14523 ? 48  LYS A N   1 
ATOM 1591 C CA  . LYS C 2 48  ? 9.67000   12.63564  31.76450  1.000 630.14523 ? 48  LYS A CA  1 
ATOM 1592 C C   . LYS C 2 48  ? 10.82400  11.64064  31.81050  1.000 630.14523 ? 48  LYS A C   1 
ATOM 1593 O O   . LYS C 2 48  ? 11.33700  11.35364  32.89550  1.000 630.14523 ? 48  LYS A O   1 
ATOM 1594 C CB  . LYS C 2 48  ? 10.13500  14.02464  32.21150  1.000 630.14523 ? 48  LYS A CB  1 
ATOM 1595 C CG  . LYS C 2 48  ? 9.74200   15.12664  31.25050  1.000 630.14523 ? 48  LYS A CG  1 
ATOM 1596 C CD  . LYS C 2 48  ? 10.26700  16.47164  31.69550  1.000 630.14523 ? 48  LYS A CD  1 
ATOM 1597 C CE  . LYS C 2 48  ? 9.80200   17.56164  30.74750  1.000 630.14523 ? 48  LYS A CE  1 
ATOM 1598 N NZ  . LYS C 2 48  ? 10.26100  18.90564  31.18650  1.000 630.14523 ? 48  LYS A NZ  1 
ATOM 1599 N N   . THR C 2 49  ? 11.25500  11.15064  30.64250  1.000 652.74147 ? 49  THR A N   1 
ATOM 1600 C CA  . THR C 2 49  ? 12.22200  10.05664  30.59550  1.000 652.74147 ? 49  THR A CA  1 
ATOM 1601 C C   . THR C 2 49  ? 13.63200  10.52064  30.94750  1.000 652.74147 ? 49  THR A C   1 
ATOM 1602 O O   . THR C 2 49  ? 13.87700  11.64864  31.37450  1.000 652.74147 ? 49  THR A O   1 
ATOM 1603 C CB  . THR C 2 49  ? 12.31100  9.41264   29.21050  1.000 652.74147 ? 49  THR A CB  1 
ATOM 1604 O OG1 . THR C 2 49  ? 12.78800  10.36664  28.25450  1.000 652.74147 ? 49  THR A OG1 1 
ATOM 1605 C CG2 . THR C 2 49  ? 11.00500  8.80564   28.75750  1.000 652.74147 ? 49  THR A CG2 1 
ATOM 1606 N N   . SER C 2 50  ? 14.57200  9.60664   30.74650  1.000 636.76751 ? 50  SER A N   1 
ATOM 1607 C CA  . SER C 2 50  ? 15.99000  9.89864   30.86350  1.000 636.76751 ? 50  SER A CA  1 
ATOM 1608 C C   . SER C 2 50  ? 16.50100  10.43964  29.53150  1.000 636.76751 ? 50  SER A C   1 
ATOM 1609 O O   . SER C 2 50  ? 15.73100  10.73464  28.61350  1.000 636.76751 ? 50  SER A O   1 
ATOM 1610 C CB  . SER C 2 50  ? 16.74800  8.64564   31.28750  1.000 636.76751 ? 50  SER A CB  1 
ATOM 1611 O OG  . SER C 2 50  ? 16.76900  7.70164   30.23050  1.000 636.76751 ? 50  SER A OG  1 
ATOM 1612 N N   . GLU C 2 51  ? 17.82400  10.57264  29.42050  1.000 573.82428 ? 51  GLU A N   1 
ATOM 1613 C CA  . GLU C 2 51  ? 18.43200  10.91864  28.14250  1.000 573.82428 ? 51  GLU A CA  1 
ATOM 1614 C C   . GLU C 2 51  ? 18.29300  9.78264   27.13850  1.000 573.82428 ? 51  GLU A C   1 
ATOM 1615 O O   . GLU C 2 51  ? 18.16000  10.03064  25.93450  1.000 573.82428 ? 51  GLU A O   1 
ATOM 1616 C CB  . GLU C 2 51  ? 19.90500  11.26664  28.34350  1.000 573.82428 ? 51  GLU A CB  1 
ATOM 1617 C CG  . GLU C 2 51  ? 20.15400  12.31264  29.41350  1.000 573.82428 ? 51  GLU A CG  1 
ATOM 1618 C CD  . GLU C 2 51  ? 19.57700  13.65964  29.05250  1.000 573.82428 ? 51  GLU A CD  1 
ATOM 1619 O OE1 . GLU C 2 51  ? 18.48100  13.98764  29.55050  1.000 573.82428 ? 51  GLU A OE1 1 
ATOM 1620 O OE2 . GLU C 2 51  ? 20.22600  14.39564  28.27950  1.000 573.82428 ? 51  GLU A OE2 1 
ATOM 1621 N N   . SER C 2 52  ? 18.31600  8.53864   27.61750  1.000 619.41740 ? 52  SER A N   1 
ATOM 1622 C CA  . SER C 2 52  ? 18.19000  7.35764   26.77650  1.000 619.41740 ? 52  SER A CA  1 
ATOM 1623 C C   . SER C 2 52  ? 16.75100  6.88064   26.64350  1.000 619.41740 ? 52  SER A C   1 
ATOM 1624 O O   . SER C 2 52  ? 16.52300  5.74364   26.22150  1.000 619.41740 ? 52  SER A O   1 
ATOM 1625 C CB  . SER C 2 52  ? 19.06800  6.22664   27.32350  1.000 619.41740 ? 52  SER A CB  1 
ATOM 1626 O OG  . SER C 2 52  ? 18.38700  4.98364   27.30850  1.000 619.41740 ? 52  SER A OG  1 
ATOM 1627 N N   . GLY C 2 53  ? 15.78000  7.71264   27.00850  1.000 608.73126 ? 53  GLY A N   1 
ATOM 1628 C CA  . GLY C 2 53  ? 14.38900  7.36264   26.81550  1.000 608.73126 ? 53  GLY A CA  1 
ATOM 1629 C C   . GLY C 2 53  ? 13.77800  6.51564   27.89250  1.000 608.73126 ? 53  GLY A C   1 
ATOM 1630 O O   . GLY C 2 53  ? 12.72700  5.90964   27.66150  1.000 608.73126 ? 53  GLY A O   1 
ATOM 1631 N N   . GLU C 2 54  ? 14.37000  6.48764   29.07850  1.000 566.72247 ? 54  GLU A N   1 
ATOM 1632 C CA  . GLU C 2 54  ? 13.93600  5.57764   30.12050  1.000 566.72247 ? 54  GLU A CA  1 
ATOM 1633 C C   . GLU C 2 54  ? 13.18700  6.32364   31.21850  1.000 566.72247 ? 54  GLU A C   1 
ATOM 1634 O O   . GLU C 2 54  ? 13.69800  7.28364   31.80650  1.000 566.72247 ? 54  GLU A O   1 
ATOM 1635 C CB  . GLU C 2 54  ? 15.13300  4.80564   30.67550  1.000 566.72247 ? 54  GLU A CB  1 
ATOM 1636 C CG  . GLU C 2 54  ? 16.01600  4.24964   29.54950  1.000 566.72247 ? 54  GLU A CG  1 
ATOM 1637 C CD  . GLU C 2 54  ? 17.17400  3.40564   30.04650  1.000 566.72247 ? 54  GLU A CD  1 
ATOM 1638 O OE1 . GLU C 2 54  ? 17.36000  3.33264   31.27550  1.000 566.72247 ? 54  GLU A OE1 1 
ATOM 1639 O OE2 . GLU C 2 54  ? 17.89700  2.82264   29.21050  1.000 566.72247 ? 54  GLU A OE2 1 
ATOM 1640 N N   . LEU C 2 55  ? 11.95800  5.87164   31.47050  1.000 562.00297 ? 55  LEU A N   1 
ATOM 1641 C CA  . LEU C 2 55  ? 11.08800  6.40264   32.51650  1.000 562.00297 ? 55  LEU A CA  1 
ATOM 1642 C C   . LEU C 2 55  ? 10.49600  5.23264   33.28350  1.000 562.00297 ? 55  LEU A C   1 
ATOM 1643 O O   . LEU C 2 55  ? 9.94900   4.30164   32.68250  1.000 562.00297 ? 55  LEU A O   1 
ATOM 1644 C CB  . LEU C 2 55  ? 9.97500   7.27464   31.93950  1.000 562.00297 ? 55  LEU A CB  1 
ATOM 1645 C CG  . LEU C 2 55  ? 8.88300   7.66864   32.93450  1.000 562.00297 ? 55  LEU A CG  1 
ATOM 1646 C CD1 . LEU C 2 55  ? 9.14700   9.01064   33.57250  1.000 562.00297 ? 55  LEU A CD1 1 
ATOM 1647 C CD2 . LEU C 2 55  ? 7.52200   7.65064   32.24950  1.000 562.00297 ? 55  LEU A CD2 1 
ATOM 1648 N N   . HIS C 2 56  ? 10.62000  5.28064   34.60450  1.000 553.72094 ? 56  HIS A N   1 
ATOM 1649 C CA  . HIS C 2 56  ? 10.20700  4.19464   35.46850  1.000 553.72094 ? 56  HIS A CA  1 
ATOM 1650 C C   . HIS C 2 56  ? 9.50800   4.77664   36.68650  1.000 553.72094 ? 56  HIS A C   1 
ATOM 1651 O O   . HIS C 2 56  ? 9.67000   5.95264   37.02050  1.000 553.72094 ? 56  HIS A O   1 
ATOM 1652 C CB  . HIS C 2 56  ? 11.41500  3.34264   35.86850  1.000 553.72094 ? 56  HIS A CB  1 
ATOM 1653 C CG  . HIS C 2 56  ? 11.93800  2.50364   34.74750  1.000 553.72094 ? 56  HIS A CG  1 
ATOM 1654 N ND1 . HIS C 2 56  ? 13.17400  2.71264   34.17650  1.000 553.72094 ? 56  HIS A ND1 1 
ATOM 1655 C CD2 . HIS C 2 56  ? 11.36800  1.49364   34.05050  1.000 553.72094 ? 56  HIS A CD2 1 
ATOM 1656 C CE1 . HIS C 2 56  ? 13.35600  1.84764   33.19750  1.000 553.72094 ? 56  HIS A CE1 1 
ATOM 1657 N NE2 . HIS C 2 56  ? 12.27600  1.09364   33.10050  1.000 553.72094 ? 56  HIS A NE2 1 
ATOM 1658 N N   . GLY C 2 57  ? 8.72500   3.94064   37.35650  1.000 628.85712 ? 57  GLY A N   1 
ATOM 1659 C CA  . GLY C 2 57  ? 8.09100   4.36464   38.58450  1.000 628.85712 ? 57  GLY A CA  1 
ATOM 1660 C C   . GLY C 2 57  ? 6.93300   5.31664   38.42150  1.000 628.85712 ? 57  GLY A C   1 
ATOM 1661 O O   . GLY C 2 57  ? 6.76700   6.21564   39.25050  1.000 628.85712 ? 57  GLY A O   1 
ATOM 1662 N N   . LEU C 2 58  ? 6.14000   5.16864   37.35650  1.000 667.55134 ? 58  LEU A N   1 
ATOM 1663 C CA  . LEU C 2 58  ? 4.88700   5.91164   37.27750  1.000 667.55134 ? 58  LEU A CA  1 
ATOM 1664 C C   . LEU C 2 58  ? 3.92300   5.46064   38.36250  1.000 667.55134 ? 58  LEU A C   1 
ATOM 1665 O O   . LEU C 2 58  ? 3.26500   6.28864   39.00150  1.000 667.55134 ? 58  LEU A O   1 
ATOM 1666 C CB  . LEU C 2 58  ? 4.25000   5.74764   35.90150  1.000 667.55134 ? 58  LEU A CB  1 
ATOM 1667 C CG  . LEU C 2 58  ? 4.97200   6.45464   34.76350  1.000 667.55134 ? 58  LEU A CG  1 
ATOM 1668 C CD1 . LEU C 2 58  ? 4.24100   6.20964   33.45850  1.000 667.55134 ? 58  LEU A CD1 1 
ATOM 1669 C CD2 . LEU C 2 58  ? 5.06300   7.93464   35.06550  1.000 667.55134 ? 58  LEU A CD2 1 
ATOM 1670 N N   . THR C 2 59  ? 3.82000   4.15064   38.57250  1.000 402.90057 ? 59  THR A N   1 
ATOM 1671 C CA  . THR C 2 59  ? 3.12800   3.57264   39.71750  1.000 402.90057 ? 59  THR A CA  1 
ATOM 1672 C C   . THR C 2 59  ? 4.08200   2.57264   40.37250  1.000 402.90057 ? 59  THR A C   1 
ATOM 1673 O O   . THR C 2 59  ? 5.24700   2.44964   39.97850  1.000 402.90057 ? 59  THR A O   1 
ATOM 1674 C CB  . THR C 2 59  ? 1.79400   2.93064   39.30050  1.000 402.90057 ? 59  THR A CB  1 
ATOM 1675 O OG1 . THR C 2 59  ? 2.02200   1.97364   38.26050  1.000 402.90057 ? 59  THR A OG1 1 
ATOM 1676 C CG2 . THR C 2 59  ? 0.79300   3.97964   38.80850  1.000 402.90057 ? 59  THR A CG2 1 
ATOM 1677 N N   . THR C 2 60  ? 3.59000   1.87164   41.39450  1.000 407.24001 ? 60  THR A N   1 
ATOM 1678 C CA  . THR C 2 60  ? 4.32700   0.79464   42.04450  1.000 407.24001 ? 60  THR A CA  1 
ATOM 1679 C C   . THR C 2 60  ? 4.42400   -0.37836  41.07750  1.000 407.24001 ? 60  THR A C   1 
ATOM 1680 O O   . THR C 2 60  ? 3.47900   -0.64736  40.33850  1.000 407.24001 ? 60  THR A O   1 
ATOM 1681 C CB  . THR C 2 60  ? 3.62600   0.36364   43.33550  1.000 407.24001 ? 60  THR A CB  1 
ATOM 1682 O OG1 . THR C 2 60  ? 2.36800   1.03964   43.44050  1.000 407.24001 ? 60  THR A OG1 1 
ATOM 1683 C CG2 . THR C 2 60  ? 4.46000   0.72964   44.55050  1.000 407.24001 ? 60  THR A CG2 1 
ATOM 1684 N N   . GLU C 2 61  ? 5.57900   -1.05636  41.06650  1.000 506.75182 ? 61  GLU A N   1 
ATOM 1685 C CA  . GLU C 2 61  ? 5.86500   -2.03036  40.01150  1.000 506.75182 ? 61  GLU A CA  1 
ATOM 1686 C C   . GLU C 2 61  ? 4.94700   -3.24536  40.06950  1.000 506.75182 ? 61  GLU A C   1 
ATOM 1687 O O   . GLU C 2 61  ? 4.48700   -3.72336  39.02650  1.000 506.75182 ? 61  GLU A O   1 
ATOM 1688 C CB  . GLU C 2 61  ? 7.31900   -2.48836  40.09550  1.000 506.75182 ? 61  GLU A CB  1 
ATOM 1689 C CG  . GLU C 2 61  ? 7.77300   -3.26636  38.87150  1.000 506.75182 ? 61  GLU A CG  1 
ATOM 1690 C CD  . GLU C 2 61  ? 9.25900   -3.15936  38.63450  1.000 506.75182 ? 61  GLU A CD  1 
ATOM 1691 O OE1 . GLU C 2 61  ? 9.74400   -3.69836  37.61650  1.000 506.75182 ? 61  GLU A OE1 1 
ATOM 1692 O OE2 . GLU C 2 61  ? 9.93800   -2.54036  39.47350  1.000 506.75182 ? 61  GLU A OE2 1 
ATOM 1693 N N   . GLU C 2 62  ? 4.65900   -3.74436  41.27150  1.000 550.69462 ? 62  GLU A N   1 
ATOM 1694 C CA  . GLU C 2 62  ? 3.84000   -4.94236  41.40350  1.000 550.69462 ? 62  GLU A CA  1 
ATOM 1695 C C   . GLU C 2 62  ? 2.40200   -4.61936  41.80350  1.000 550.69462 ? 62  GLU A C   1 
ATOM 1696 O O   . GLU C 2 62  ? 1.49300   -5.40136  41.50650  1.000 550.69462 ? 62  GLU A O   1 
ATOM 1697 C CB  . GLU C 2 62  ? 4.45300   -5.96936  42.39050  1.000 550.69462 ? 62  GLU A CB  1 
ATOM 1698 C CG  . GLU C 2 62  ? 5.85000   -5.86336  43.20950  1.000 550.69462 ? 62  GLU A CG  1 
ATOM 1699 C CD  . GLU C 2 62  ? 6.45900   -4.50236  43.63150  1.000 550.69462 ? 62  GLU A CD  1 
ATOM 1700 O OE1 . GLU C 2 62  ? 6.02200   -3.42236  43.19150  1.000 550.69462 ? 62  GLU A OE1 1 
ATOM 1701 O OE2 . GLU C 2 62  ? 7.42400   -4.52936  44.43450  1.000 550.69462 ? 62  GLU A OE2 1 
ATOM 1702 N N   . GLU C 2 63  ? 2.17100   -3.48636  42.47250  1.000 545.86973 ? 63  GLU A N   1 
ATOM 1703 C CA  . GLU C 2 63  ? 0.80800   -3.08736  42.80750  1.000 545.86973 ? 63  GLU A CA  1 
ATOM 1704 C C   . GLU C 2 63  ? 0.04300   -2.62936  41.57050  1.000 545.86973 ? 63  GLU A C   1 
ATOM 1705 O O   . GLU C 2 63  ? -1.18700  -2.74436  41.53750  1.000 545.86973 ? 63  GLU A O   1 
ATOM 1706 C CB  . GLU C 2 63  ? 0.85700   -2.00236  43.89950  1.000 545.86973 ? 63  GLU A CB  1 
ATOM 1707 C CG  . GLU C 2 63  ? -0.46100  -1.32536  44.30750  1.000 545.86973 ? 63  GLU A CG  1 
ATOM 1708 C CD  . GLU C 2 63  ? -0.76900  -0.08936  43.47150  1.000 545.86973 ? 63  GLU A CD  1 
ATOM 1709 O OE1 . GLU C 2 63  ? -1.89700  0.43364   43.55950  1.000 545.86973 ? 63  GLU A OE1 1 
ATOM 1710 O OE2 . GLU C 2 63  ? 0.13000   0.33964   42.72250  1.000 545.86973 ? 63  GLU A OE2 1 
ATOM 1711 N N   . PHE C 2 64  ? 0.74100   -2.16036  40.54150  1.000 381.06774 ? 64  PHE A N   1 
ATOM 1712 C CA  . PHE C 2 64  ? 0.11100   -1.85636  39.25850  1.000 381.06774 ? 64  PHE A CA  1 
ATOM 1713 C C   . PHE C 2 64  ? -0.37000  -3.15836  38.63850  1.000 381.06774 ? 64  PHE A C   1 
ATOM 1714 O O   . PHE C 2 64  ? 0.41300   -4.05936  38.33250  1.000 381.06774 ? 64  PHE A O   1 
ATOM 1715 C CB  . PHE C 2 64  ? 1.08300   -1.13736  38.34150  1.000 381.06774 ? 64  PHE A CB  1 
ATOM 1716 C CG  . PHE C 2 64  ? 0.71400   -1.19536  36.90650  1.000 381.06774 ? 64  PHE A CG  1 
ATOM 1717 C CD1 . PHE C 2 64  ? -0.36600  -0.47436  36.42550  1.000 381.06774 ? 64  PHE A CD1 1 
ATOM 1718 C CD2 . PHE C 2 64  ? 1.46000   -1.96436  36.02850  1.000 381.06774 ? 64  PHE A CD2 1 
ATOM 1719 C CE1 . PHE C 2 64  ? -0.69700  -0.52436  35.09350  1.000 381.06774 ? 64  PHE A CE1 1 
ATOM 1720 C CE2 . PHE C 2 64  ? 1.13200   -2.02336  34.70250  1.000 381.06774 ? 64  PHE A CE2 1 
ATOM 1721 C CZ  . PHE C 2 64  ? 0.05400   -1.30436  34.23350  1.000 381.06774 ? 64  PHE A CZ  1 
ATOM 1722 N N   . VAL C 2 65  ? -1.68300  -3.25736  38.46650  1.000 383.72683 ? 65  VAL A N   1 
ATOM 1723 C CA  . VAL C 2 65  ? -2.27900  -4.44036  37.86050  1.000 383.72683 ? 65  VAL A CA  1 
ATOM 1724 C C   . VAL C 2 65  ? -1.97500  -4.45636  36.36350  1.000 383.72683 ? 65  VAL A C   1 
ATOM 1725 O O   . VAL C 2 65  ? -1.86800  -3.41436  35.71150  1.000 383.72683 ? 65  VAL A O   1 
ATOM 1726 C CB  . VAL C 2 65  ? -3.79800  -4.50536  38.16250  1.000 383.72683 ? 65  VAL A CB  1 
ATOM 1727 C CG1 . VAL C 2 65  ? -4.21900  -3.35736  39.08150  1.000 383.72683 ? 65  VAL A CG1 1 
ATOM 1728 C CG2 . VAL C 2 65  ? -4.68700  -4.53236  36.90750  1.000 383.72683 ? 65  VAL A CG2 1 
ATOM 1729 N N   . GLU C 2 66  ? -1.76800  -5.65936  35.82750  1.000 412.94699 ? 66  GLU A N   1 
ATOM 1730 C CA  . GLU C 2 66  ? -1.36600  -5.80236  34.43750  1.000 412.94699 ? 66  GLU A CA  1 
ATOM 1731 C C   . GLU C 2 66  ? -2.53200  -5.50636  33.49550  1.000 412.94699 ? 66  GLU A C   1 
ATOM 1732 O O   . GLU C 2 66  ? -3.70300  -5.50636  33.88450  1.000 412.94699 ? 66  GLU A O   1 
ATOM 1733 C CB  . GLU C 2 66  ? -0.83700  -7.21236  34.17350  1.000 412.94699 ? 66  GLU A CB  1 
ATOM 1734 C CG  . GLU C 2 66  ? 0.48300   -7.53636  34.85550  1.000 412.94699 ? 66  GLU A CG  1 
ATOM 1735 C CD  . GLU C 2 66  ? 0.28500   -8.27036  36.16750  1.000 412.94699 ? 66  GLU A CD  1 
ATOM 1736 O OE1 . GLU C 2 66  ? -0.88000  -8.56136  36.51050  1.000 412.94699 ? 66  GLU A OE1 1 
ATOM 1737 O OE2 . GLU C 2 66  ? 1.28900   -8.57536  36.84550  1.000 412.94699 ? 66  GLU A OE2 1 
ATOM 1738 N N   . GLY C 2 67  ? -2.19600  -5.26436  32.23550  1.000 469.71876 ? 67  GLY A N   1 
ATOM 1739 C CA  . GLY C 2 67  ? -3.20500  -4.98236  31.23550  1.000 469.71876 ? 67  GLY A CA  1 
ATOM 1740 C C   . GLY C 2 67  ? -2.57700  -4.37836  29.99350  1.000 469.71876 ? 67  GLY A C   1 
ATOM 1741 O O   . GLY C 2 67  ? -1.38400  -4.53736  29.73850  1.000 469.71876 ? 67  GLY A O   1 
ATOM 1742 N N   . ILE C 2 68  ? -3.41700  -3.68536  29.22950  1.000 509.95996 ? 68  ILE A N   1 
ATOM 1743 C CA  . ILE C 2 68  ? -2.97800  -3.00636  28.01850  1.000 509.95996 ? 68  ILE A CA  1 
ATOM 1744 C C   . ILE C 2 68  ? -2.37500  -1.68336  28.47250  1.000 509.95996 ? 68  ILE A C   1 
ATOM 1745 O O   . ILE C 2 68  ? -3.05200  -0.65936  28.53250  1.000 509.95996 ? 68  ILE A O   1 
ATOM 1746 C CB  . ILE C 2 68  ? -4.12900  -2.80236  27.03350  1.000 509.95996 ? 68  ILE A CB  1 
ATOM 1747 C CG1 . ILE C 2 68  ? -4.99000  -4.06236  26.96950  1.000 509.95996 ? 68  ILE A CG1 1 
ATOM 1748 C CG2 . ILE C 2 68  ? -3.59600  -2.44336  25.65450  1.000 509.95996 ? 68  ILE A CG2 1 
ATOM 1749 C CD1 . ILE C 2 68  ? -6.21400  -3.91936  26.10850  1.000 509.95996 ? 68  ILE A CD1 1 
ATOM 1750 N N   . TYR C 2 69  ? -1.09300  -1.71536  28.81950  1.000 468.08919 ? 69  TYR A N   1 
ATOM 1751 C CA  . TYR C 2 69  ? -0.39600  -0.53836  29.30750  1.000 468.08919 ? 69  TYR A CA  1 
ATOM 1752 C C   . TYR C 2 69  ? 1.01500   -0.54336  28.74550  1.000 468.08919 ? 69  TYR A C   1 
ATOM 1753 O O   . TYR C 2 69  ? 1.47400   -1.54536  28.19050  1.000 468.08919 ? 69  TYR A O   1 
ATOM 1754 C CB  . TYR C 2 69  ? -0.38700  -0.47636  30.83650  1.000 468.08919 ? 69  TYR A CB  1 
ATOM 1755 C CG  . TYR C 2 69  ? -1.76600  -0.26636  31.41850  1.000 468.08919 ? 69  TYR A CG  1 
ATOM 1756 C CD1 . TYR C 2 69  ? -2.52400  -1.34036  31.87050  1.000 468.08919 ? 69  TYR A CD1 1 
ATOM 1757 C CD2 . TYR C 2 69  ? -2.32500  1.00464   31.47850  1.000 468.08919 ? 69  TYR A CD2 1 
ATOM 1758 C CE1 . TYR C 2 69  ? -3.79200  -1.15236  32.38750  1.000 468.08919 ? 69  TYR A CE1 1 
ATOM 1759 C CE2 . TYR C 2 69  ? -3.59200  1.20264   31.99350  1.000 468.08919 ? 69  TYR A CE2 1 
ATOM 1760 C CZ  . TYR C 2 69  ? -4.32000  0.12164   32.44650  1.000 468.08919 ? 69  TYR A CZ  1 
ATOM 1761 O OH  . TYR C 2 69  ? -5.58100  0.31464   32.95950  1.000 468.08919 ? 69  TYR A OH  1 
ATOM 1762 N N   . LYS C 2 70  ? 1.70100   0.58464   28.90050  1.000 647.58722 ? 70  LYS A N   1 
ATOM 1763 C CA  . LYS C 2 70  ? 2.77700   0.94264   27.98850  1.000 647.58722 ? 70  LYS A CA  1 
ATOM 1764 C C   . LYS C 2 70  ? 3.74100   1.88764   28.68450  1.000 647.58722 ? 70  LYS A C   1 
ATOM 1765 O O   . LYS C 2 70  ? 3.37000   2.54864   29.65750  1.000 647.58722 ? 70  LYS A O   1 
ATOM 1766 C CB  . LYS C 2 70  ? 2.16900   1.60164   26.74750  1.000 647.58722 ? 70  LYS A CB  1 
ATOM 1767 C CG  . LYS C 2 70  ? 3.00200   1.64564   25.49150  1.000 647.58722 ? 70  LYS A CG  1 
ATOM 1768 C CD  . LYS C 2 70  ? 2.08800   2.09664   24.35850  1.000 647.58722 ? 70  LYS A CD  1 
ATOM 1769 C CE  . LYS C 2 70  ? 2.79300   2.14964   23.02750  1.000 647.58722 ? 70  LYS A CE  1 
ATOM 1770 N NZ  . LYS C 2 70  ? 1.87300   2.55664   21.93050  1.000 647.58722 ? 70  LYS A NZ  1 
ATOM 1771 N N   . VAL C 2 71  ? 4.98500   1.92264   28.21350  1.000 781.00324 ? 71  VAL A N   1 
ATOM 1772 C CA  . VAL C 2 71  ? 5.88400   3.03864   28.49150  1.000 781.00324 ? 71  VAL A CA  1 
ATOM 1773 C C   . VAL C 2 71  ? 6.14300   3.70964   27.14750  1.000 781.00324 ? 71  VAL A C   1 
ATOM 1774 O O   . VAL C 2 71  ? 7.10200   3.37564   26.45250  1.000 781.00324 ? 71  VAL A O   1 
ATOM 1775 C CB  . VAL C 2 71  ? 7.18500   2.58564   29.15350  1.000 781.00324 ? 71  VAL A CB  1 
ATOM 1776 C CG1 . VAL C 2 71  ? 7.94600   3.79064   29.67250  1.000 781.00324 ? 71  VAL A CG1 1 
ATOM 1777 C CG2 . VAL C 2 71  ? 6.90600   1.60164   30.27250  1.000 781.00324 ? 71  VAL A CG2 1 
ATOM 1778 N N   . GLU C 2 72  ? 5.29500   4.65864   26.77750  1.000 625.51730 ? 72  GLU A N   1 
ATOM 1779 C CA  . GLU C 2 72  ? 5.29400   5.20264   25.42850  1.000 625.51730 ? 72  GLU A CA  1 
ATOM 1780 C C   . GLU C 2 72  ? 6.19900   6.42264   25.35450  1.000 625.51730 ? 72  GLU A C   1 
ATOM 1781 O O   . GLU C 2 72  ? 6.18600   7.26864   26.25250  1.000 625.51730 ? 72  GLU A O   1 
ATOM 1782 C CB  . GLU C 2 72  ? 3.87700   5.56964   24.98750  1.000 625.51730 ? 72  GLU A CB  1 
ATOM 1783 C CG  . GLU C 2 72  ? 3.70100   5.66664   23.47550  1.000 625.51730 ? 72  GLU A CG  1 
ATOM 1784 C CD  . GLU C 2 72  ? 2.26400   5.95564   23.07450  1.000 625.51730 ? 72  GLU A CD  1 
ATOM 1785 O OE1 . GLU C 2 72  ? 1.70300   6.95764   23.56750  1.000 625.51730 ? 72  GLU A OE1 1 
ATOM 1786 O OE2 . GLU C 2 72  ? 1.69300   5.19864   22.25850  1.000 625.51730 ? 72  GLU A OE2 1 
ATOM 1787 N N   . ILE C 2 73  ? 6.98900   6.49964   24.29150  1.000 508.39850 ? 73  ILE A N   1 
ATOM 1788 C CA  . ILE C 2 73  ? 7.74700   7.69964   23.96750  1.000 508.39850 ? 73  ILE A CA  1 
ATOM 1789 C C   . ILE C 2 73  ? 6.81700   8.57464   23.12150  1.000 508.39850 ? 73  ILE A C   1 
ATOM 1790 O O   . ILE C 2 73  ? 6.83300   8.51164   21.88850  1.000 508.39850 ? 73  ILE A O   1 
ATOM 1791 C CB  . ILE C 2 73  ? 9.05700   7.34064   23.24750  1.000 508.39850 ? 73  ILE A CB  1 
ATOM 1792 C CG1 . ILE C 2 73  ? 9.89800   6.38864   24.11450  1.000 508.39850 ? 73  ILE A CG1 1 
ATOM 1793 C CG2 . ILE C 2 73  ? 9.88400   8.55464   22.94950  1.000 508.39850 ? 73  ILE A CG2 1 
ATOM 1794 C CD1 . ILE C 2 73  ? 11.30900  6.11164   23.58150  1.000 508.39850 ? 73  ILE A CD1 1 
ATOM 1795 N N   . ASP C 2 74  ? 5.99000   9.39064   23.78650  1.000 581.84787 ? 74  ASP A N   1 
ATOM 1796 C CA  . ASP C 2 74  ? 4.82400   10.01564  23.15950  1.000 581.84787 ? 74  ASP A CA  1 
ATOM 1797 C C   . ASP C 2 74  ? 5.22800   11.25664  22.37650  1.000 581.84787 ? 74  ASP A C   1 
ATOM 1798 O O   . ASP C 2 74  ? 5.95300   12.11364  22.88850  1.000 581.84787 ? 74  ASP A O   1 
ATOM 1799 C CB  . ASP C 2 74  ? 3.76400   10.39564  24.19450  1.000 581.84787 ? 74  ASP A CB  1 
ATOM 1800 C CG  . ASP C 2 74  ? 2.73000   11.37164  23.63550  1.000 581.84787 ? 74  ASP A CG  1 
ATOM 1801 O OD1 . ASP C 2 74  ? 1.98700   10.99164  22.70650  1.000 581.84787 ? 74  ASP A OD1 1 
ATOM 1802 O OD2 . ASP C 2 74  ? 2.66400   12.52064  24.11150  1.000 581.84787 ? 74  ASP A OD2 1 
ATOM 1803 N N   . THR C 2 75  ? 4.72800   11.36364  21.14650  1.000 570.40028 ? 75  THR A N   1 
ATOM 1804 C CA  . THR C 2 75  ? 5.07000   12.51464  20.32750  1.000 570.40028 ? 75  THR A CA  1 
ATOM 1805 C C   . THR C 2 75  ? 4.29500   13.75164  20.74450  1.000 570.40028 ? 75  THR A C   1 
ATOM 1806 O O   . THR C 2 75  ? 4.79400   14.87064  20.59350  1.000 570.40028 ? 75  THR A O   1 
ATOM 1807 C CB  . THR C 2 75  ? 4.79500   12.22464  18.85950  1.000 570.40028 ? 75  THR A CB  1 
ATOM 1808 O OG1 . THR C 2 75  ? 3.40100   12.41064  18.60050  1.000 570.40028 ? 75  THR A OG1 1 
ATOM 1809 C CG2 . THR C 2 75  ? 5.15900   10.79564  18.54550  1.000 570.40028 ? 75  THR A CG2 1 
ATOM 1810 N N   . LYS C 2 76  ? 3.08300   13.57264  21.26950  1.000 522.84277 ? 76  LYS A N   1 
ATOM 1811 C CA  . LYS C 2 76  ? 2.22500   14.71464  21.55750  1.000 522.84277 ? 76  LYS A CA  1 
ATOM 1812 C C   . LYS C 2 76  ? 2.73900   15.55464  22.71750  1.000 522.84277 ? 76  LYS A C   1 
ATOM 1813 O O   . LYS C 2 76  ? 2.81100   16.78364  22.60450  1.000 522.84277 ? 76  LYS A O   1 
ATOM 1814 C CB  . LYS C 2 76  ? 0.80900   14.23164  21.83950  1.000 522.84277 ? 76  LYS A CB  1 
ATOM 1815 C CG  . LYS C 2 76  ? -0.03900  15.19164  22.65350  1.000 522.84277 ? 76  LYS A CG  1 
ATOM 1816 C CD  . LYS C 2 76  ? -1.19600  14.48364  23.34350  1.000 522.84277 ? 76  LYS A CD  1 
ATOM 1817 C CE  . LYS C 2 76  ? -0.75200  13.24864  24.10150  1.000 522.84277 ? 76  LYS A CE  1 
ATOM 1818 N NZ  . LYS C 2 76  ? 0.28600   13.59964  25.08150  1.000 522.84277 ? 76  LYS A NZ  1 
ATOM 1819 N N   . SER C 2 77  ? 3.14500   14.92564  23.81250  1.000 548.53034 ? 77  SER A N   1 
ATOM 1820 C CA  . SER C 2 77  ? 3.51700   15.67964  24.99950  1.000 548.53034 ? 77  SER A CA  1 
ATOM 1821 C C   . SER C 2 77  ? 5.00100   16.00364  25.06550  1.000 548.53034 ? 77  SER A C   1 
ATOM 1822 O O   . SER C 2 77  ? 5.38000   17.00464  25.68150  1.000 548.53034 ? 77  SER A O   1 
ATOM 1823 C CB  . SER C 2 77  ? 3.09400   14.91764  26.25250  1.000 548.53034 ? 77  SER A CB  1 
ATOM 1824 O OG  . SER C 2 77  ? 4.20600   14.48364  26.99550  1.000 548.53034 ? 77  SER A OG  1 
ATOM 1825 N N   . TYR C 2 78  ? 5.85400   15.18864  24.44350  1.000 462.03287 ? 78  TYR A N   1 
ATOM 1826 C CA  . TYR C 2 78  ? 7.27600   15.50564  24.44450  1.000 462.03287 ? 78  TYR A CA  1 
ATOM 1827 C C   . TYR C 2 78  ? 7.58400   16.65664  23.50750  1.000 462.03287 ? 78  TYR A C   1 
ATOM 1828 O O   . TYR C 2 78  ? 8.24000   17.62464  23.90350  1.000 462.03287 ? 78  TYR A O   1 
ATOM 1829 C CB  . TYR C 2 78  ? 8.09600   14.29364  24.03950  1.000 462.03287 ? 78  TYR A CB  1 
ATOM 1830 C CG  . TYR C 2 78  ? 9.50900   14.64064  23.64150  1.000 462.03287 ? 78  TYR A CG  1 
ATOM 1831 C CD1 . TYR C 2 78  ? 10.42100  15.09964  24.57850  1.000 462.03287 ? 78  TYR A CD1 1 
ATOM 1832 C CD2 . TYR C 2 78  ? 9.92600   14.52764  22.32750  1.000 462.03287 ? 78  TYR A CD2 1 
ATOM 1833 C CE1 . TYR C 2 78  ? 11.71500  15.40264  24.22750  1.000 462.03287 ? 78  TYR A CE1 1 
ATOM 1834 C CE2 . TYR C 2 78  ? 11.21900  14.82964  21.96150  1.000 462.03287 ? 78  TYR A CE2 1 
ATOM 1835 C CZ  . TYR C 2 78  ? 12.11100  15.26764  22.91550  1.000 462.03287 ? 78  TYR A CZ  1 
ATOM 1836 O OH  . TYR C 2 78  ? 13.40200  15.58164  22.56350  1.000 462.03287 ? 78  TYR A OH  1 
ATOM 1837 N N   . TRP C 2 79  ? 7.12100   16.57264  22.26050  1.000 381.49953 ? 79  TRP A N   1 
ATOM 1838 C CA  . TRP C 2 79  ? 7.43100   17.60664  21.28650  1.000 381.49953 ? 79  TRP A CA  1 
ATOM 1839 C C   . TRP C 2 79  ? 6.67400   18.90164  21.54750  1.000 381.49953 ? 79  TRP A C   1 
ATOM 1840 O O   . TRP C 2 79  ? 6.99600   19.91764  20.92450  1.000 381.49953 ? 79  TRP A O   1 
ATOM 1841 C CB  . TRP C 2 79  ? 7.13700   17.11264  19.86850  1.000 381.49953 ? 79  TRP A CB  1 
ATOM 1842 C CG  . TRP C 2 79  ? 7.96500   15.93264  19.44450  1.000 381.49953 ? 79  TRP A CG  1 
ATOM 1843 C CD1 . TRP C 2 79  ? 7.52200   14.67064  19.23150  1.000 381.49953 ? 79  TRP A CD1 1 
ATOM 1844 C CD2 . TRP C 2 79  ? 9.37300   15.90764  19.17750  1.000 381.49953 ? 79  TRP A CD2 1 
ATOM 1845 N NE1 . TRP C 2 79  ? 8.55100   13.85264  18.85350  1.000 381.49953 ? 79  TRP A NE1 1 
ATOM 1846 C CE2 . TRP C 2 79  ? 9.70300   14.59064  18.81050  1.000 381.49953 ? 79  TRP A CE2 1 
ATOM 1847 C CE3 . TRP C 2 79  ? 10.38500  16.86964  19.20850  1.000 381.49953 ? 79  TRP A CE3 1 
ATOM 1848 C CZ2 . TRP C 2 79  ? 11.00000  14.21064  18.47950  1.000 381.49953 ? 79  TRP A CZ2 1 
ATOM 1849 C CZ3 . TRP C 2 79  ? 11.67300  16.48864  18.88350  1.000 381.49953 ? 79  TRP A CZ3 1 
ATOM 1850 C CH2 . TRP C 2 79  ? 11.96900  15.17064  18.52850  1.000 381.49953 ? 79  TRP A CH2 1 
ATOM 1851 N N   . LYS C 2 80  ? 5.68500   18.88664  22.44750  1.000 321.79668 ? 80  LYS A N   1 
ATOM 1852 C CA  . LYS C 2 80  ? 5.09600   20.12464  22.94850  1.000 321.79668 ? 80  LYS A CA  1 
ATOM 1853 C C   . LYS C 2 80  ? 6.10600   20.93664  23.75150  1.000 321.79668 ? 80  LYS A C   1 
ATOM 1854 O O   . LYS C 2 80  ? 6.09900   22.17364  23.68650  1.000 321.79668 ? 80  LYS A O   1 
ATOM 1855 C CB  . LYS C 2 80  ? 3.86100   19.79964  23.79650  1.000 321.79668 ? 80  LYS A CB  1 
ATOM 1856 C CG  . LYS C 2 80  ? 3.21400   20.98564  24.51950  1.000 321.79668 ? 80  LYS A CG  1 
ATOM 1857 C CD  . LYS C 2 80  ? 2.77100   22.08564  23.55950  1.000 321.79668 ? 80  LYS A CD  1 
ATOM 1858 C CE  . LYS C 2 80  ? 1.59100   21.65464  22.70650  1.000 321.79668 ? 80  LYS A CE  1 
ATOM 1859 N NZ  . LYS C 2 80  ? 0.34800   21.52664  23.51350  1.000 321.79668 ? 80  LYS A NZ  1 
ATOM 1860 N N   . ALA C 2 81  ? 7.00600   20.26464  24.47350  1.000 413.91412 ? 81  ALA A N   1 
ATOM 1861 C CA  . ALA C 2 81  ? 8.02800   20.96264  25.24450  1.000 413.91412 ? 81  ALA A CA  1 
ATOM 1862 C C   . ALA C 2 81  ? 9.06000   21.64964  24.35850  1.000 413.91412 ? 81  ALA A C   1 
ATOM 1863 O O   . ALA C 2 81  ? 9.76300   22.54764  24.83150  1.000 413.91412 ? 81  ALA A O   1 
ATOM 1864 C CB  . ALA C 2 81  ? 8.72100   19.98864  26.19750  1.000 413.91412 ? 81  ALA A CB  1 
ATOM 1865 N N   . LEU C 2 82  ? 9.16100   21.25664  23.08950  1.000 420.72308 ? 82  LEU A N   1 
ATOM 1866 C CA  . LEU C 2 82  ? 10.03600  21.91164  22.12950  1.000 420.72308 ? 82  LEU A CA  1 
ATOM 1867 C C   . LEU C 2 82  ? 9.30300   22.91164  21.24450  1.000 420.72308 ? 82  LEU A C   1 
ATOM 1868 O O   . LEU C 2 82  ? 9.94800   23.60564  20.45450  1.000 420.72308 ? 82  LEU A O   1 
ATOM 1869 C CB  . LEU C 2 82  ? 10.74600  20.86864  21.25750  1.000 420.72308 ? 82  LEU A CB  1 
ATOM 1870 C CG  . LEU C 2 82  ? 11.65400  19.86664  21.97850  1.000 420.72308 ? 82  LEU A CG  1 
ATOM 1871 C CD1 . LEU C 2 82  ? 10.95700  18.55264  22.27050  1.000 420.72308 ? 82  LEU A CD1 1 
ATOM 1872 C CD2 . LEU C 2 82  ? 12.92300  19.62964  21.17050  1.000 420.72308 ? 82  LEU A CD2 1 
ATOM 1873 N N   . GLY C 2 83  ? 7.98100   23.00064  21.35450  1.000 392.05943 ? 83  GLY A N   1 
ATOM 1874 C CA  . GLY C 2 83  ? 7.22400   24.00664  20.63950  1.000 392.05943 ? 83  GLY A CA  1 
ATOM 1875 C C   . GLY C 2 83  ? 6.87100   23.67764  19.20750  1.000 392.05943 ? 83  GLY A C   1 
ATOM 1876 O O   . GLY C 2 83  ? 6.37100   24.55564  18.49750  1.000 392.05943 ? 83  GLY A O   1 
ATOM 1877 N N   . ILE C 2 84  ? 7.09800   22.44964  18.76050  1.000 271.32191 ? 84  ILE A N   1 
ATOM 1878 C CA  . ILE C 2 84  ? 6.72500   22.02364  17.41750  1.000 271.32191 ? 84  ILE A CA  1 
ATOM 1879 C C   . ILE C 2 84  ? 5.47200   21.16364  17.49850  1.000 271.32191 ? 84  ILE A C   1 
ATOM 1880 O O   . ILE C 2 84  ? 5.20600   20.49864  18.50550  1.000 271.32191 ? 84  ILE A O   1 
ATOM 1881 C CB  . ILE C 2 84  ? 7.89700   21.29864  16.72650  1.000 271.32191 ? 84  ILE A CB  1 
ATOM 1882 C CG1 . ILE C 2 84  ? 8.22000   19.98364  17.42950  1.000 271.32191 ? 84  ILE A CG1 1 
ATOM 1883 C CG2 . ILE C 2 84  ? 9.11800   22.21664  16.67250  1.000 271.32191 ? 84  ILE A CG2 1 
ATOM 1884 C CD1 . ILE C 2 84  ? 9.27300   19.20064  16.72850  1.000 271.32191 ? 84  ILE A CD1 1 
ATOM 1885 N N   . SER C 2 85  ? 4.66400   21.21764  16.43750  1.000 182.32477 ? 85  SER A N   1 
ATOM 1886 C CA  . SER C 2 85  ? 3.33800   20.60664  16.44850  1.000 182.32477 ? 85  SER A CA  1 
ATOM 1887 C C   . SER C 2 85  ? 3.44600   19.11564  16.17050  1.000 182.32477 ? 85  SER A C   1 
ATOM 1888 O O   . SER C 2 85  ? 4.03700   18.72564  15.15750  1.000 182.32477 ? 85  SER A O   1 
ATOM 1889 C CB  . SER C 2 85  ? 2.43000   21.26964  15.41850  1.000 182.32477 ? 85  SER A CB  1 
ATOM 1890 O OG  . SER C 2 85  ? 1.83100   20.31564  14.57250  1.000 182.32477 ? 85  SER A OG  1 
ATOM 1891 N N   . PRO C 2 86  ? 2.93600   18.25364  17.04150  1.000 187.58742 ? 86  PRO A N   1 
ATOM 1892 C CA  . PRO C 2 86  ? 2.89500   16.81664  16.76950  1.000 187.58742 ? 86  PRO A CA  1 
ATOM 1893 C C   . PRO C 2 86  ? 1.55700   16.43064  16.14750  1.000 187.58742 ? 86  PRO A C   1 
ATOM 1894 O O   . PRO C 2 86  ? 0.62700   17.22864  16.07550  1.000 187.58742 ? 86  PRO A O   1 
ATOM 1895 C CB  . PRO C 2 86  ? 3.06800   16.18964  18.16050  1.000 187.58742 ? 86  PRO A CB  1 
ATOM 1896 C CG  . PRO C 2 86  ? 3.07300   17.35064  19.15150  1.000 187.58742 ? 86  PRO A CG  1 
ATOM 1897 C CD  . PRO C 2 86  ? 2.56900   18.54664  18.42950  1.000 187.58742 ? 86  PRO A CD  1 
ATOM 1898 N N   . PHE C 2 87  ? 1.48200   15.19564  15.65650  1.000 314.52192 ? 87  PHE A N   1 
ATOM 1899 C CA  . PHE C 2 87  ? 0.22100   14.63564  15.18650  1.000 314.52192 ? 87  PHE A CA  1 
ATOM 1900 C C   . PHE C 2 87  ? -0.14300  13.33464  15.88550  1.000 314.52192 ? 87  PHE A C   1 
ATOM 1901 O O   . PHE C 2 87  ? -1.31600  13.11264  16.19450  1.000 314.52192 ? 87  PHE A O   1 
ATOM 1902 C CB  . PHE C 2 87  ? 0.27100   14.45064  13.65750  1.000 314.52192 ? 87  PHE A CB  1 
ATOM 1903 C CG  . PHE C 2 87  ? -0.62100  13.35964  13.12250  1.000 314.52192 ? 87  PHE A CG  1 
ATOM 1904 C CD1 . PHE C 2 87  ? -2.00200  13.50664  13.09750  1.000 314.52192 ? 87  PHE A CD1 1 
ATOM 1905 C CD2 . PHE C 2 87  ? -0.06700  12.20464  12.59050  1.000 314.52192 ? 87  PHE A CD2 1 
ATOM 1906 C CE1 . PHE C 2 87  ? -2.80900  12.50264  12.59450  1.000 314.52192 ? 87  PHE A CE1 1 
ATOM 1907 C CE2 . PHE C 2 87  ? -0.86800  11.20564  12.07550  1.000 314.52192 ? 87  PHE A CE2 1 
ATOM 1908 C CZ  . PHE C 2 87  ? -2.23900  11.35064  12.08250  1.000 314.52192 ? 87  PHE A CZ  1 
ATOM 1909 N N   . HIS C 2 88  ? 0.82300   12.46564  16.15550  1.000 566.84250 ? 88  HIS A N   1 
ATOM 1910 C CA  . HIS C 2 88  ? 0.49700   11.18164  16.76950  1.000 566.84250 ? 88  HIS A CA  1 
ATOM 1911 C C   . HIS C 2 88  ? 0.51400   11.29564  18.28650  1.000 566.84250 ? 88  HIS A C   1 
ATOM 1912 O O   . HIS C 2 88  ? 1.52900   11.04964  18.94050  1.000 566.84250 ? 88  HIS A O   1 
ATOM 1913 C CB  . HIS C 2 88  ? 1.44200   10.09664  16.27850  1.000 566.84250 ? 88  HIS A CB  1 
ATOM 1914 C CG  . HIS C 2 88  ? 0.89900   9.30864   15.12850  1.000 566.84250 ? 88  HIS A CG  1 
ATOM 1915 N ND1 . HIS C 2 88  ? 1.69200   8.52964   14.31450  1.000 566.84250 ? 88  HIS A ND1 1 
ATOM 1916 C CD2 . HIS C 2 88  ? -0.36800  9.15164   14.67850  1.000 566.84250 ? 88  HIS A CD2 1 
ATOM 1917 C CE1 . HIS C 2 88  ? 0.94200   7.94864   13.39550  1.000 566.84250 ? 88  HIS A CE1 1 
ATOM 1918 N NE2 . HIS C 2 88  ? -0.31300  8.30764   13.59650  1.000 566.84250 ? 88  HIS A NE2 1 
ATOM 1919 N N   . GLU C 2 89  ? -0.62700  11.68864  18.84550  1.000 684.41227 ? 89  GLU A N   1 
ATOM 1920 C CA  . GLU C 2 89  ? -0.89800  11.43464  20.25350  1.000 684.41227 ? 89  GLU A CA  1 
ATOM 1921 C C   . GLU C 2 89  ? -1.02900  9.94264   20.51450  1.000 684.41227 ? 89  GLU A C   1 
ATOM 1922 O O   . GLU C 2 89  ? -0.59300  9.44364   21.55650  1.000 684.41227 ? 89  GLU A O   1 
ATOM 1923 C CB  . GLU C 2 89  ? -2.14100  12.22964  20.66150  1.000 684.41227 ? 89  GLU A CB  1 
ATOM 1924 C CG  . GLU C 2 89  ? -3.37300  11.49064  21.14150  1.000 684.41227 ? 89  GLU A CG  1 
ATOM 1925 C CD  . GLU C 2 89  ? -4.43300  11.46464  20.05650  1.000 684.41227 ? 89  GLU A CD  1 
ATOM 1926 O OE1 . GLU C 2 89  ? -5.54600  10.95164  20.29450  1.000 684.41227 ? 89  GLU A OE1 1 
ATOM 1927 O OE2 . GLU C 2 89  ? -4.13400  11.93064  18.93450  1.000 684.41227 ? 89  GLU A OE2 1 
ATOM 1928 N N   . HIS C 2 90  ? -1.59300  9.21364   19.55950  1.000 698.66139 ? 90  HIS A N   1 
ATOM 1929 C CA  . HIS C 2 90  ? -1.44000  7.77164   19.46450  1.000 698.66139 ? 90  HIS A CA  1 
ATOM 1930 C C   . HIS C 2 90  ? -1.61800  7.39764   18.00250  1.000 698.66139 ? 90  HIS A C   1 
ATOM 1931 O O   . HIS C 2 90  ? -1.97400  8.23664   17.16950  1.000 698.66139 ? 90  HIS A O   1 
ATOM 1932 C CB  . HIS C 2 90  ? -2.43500  7.02464   20.35150  1.000 698.66139 ? 90  HIS A CB  1 
ATOM 1933 C CG  . HIS C 2 90  ? -3.85700  7.40964   20.11750  1.000 698.66139 ? 90  HIS A CG  1 
ATOM 1934 N ND1 . HIS C 2 90  ? -4.56700  7.01964   19.00350  1.000 698.66139 ? 90  HIS A ND1 1 
ATOM 1935 C CD2 . HIS C 2 90  ? -4.72000  8.11164   20.88450  1.000 698.66139 ? 90  HIS A CD2 1 
ATOM 1936 C CE1 . HIS C 2 90  ? -5.80000  7.48364   19.08550  1.000 698.66139 ? 90  HIS A CE1 1 
ATOM 1937 N NE2 . HIS C 2 90  ? -5.91800  8.15064   20.21750  1.000 698.66139 ? 90  HIS A NE2 1 
ATOM 1938 N N   . ALA C 2 91  ? -1.39500  6.12864   17.69550  1.000 637.53539 ? 91  ALA A N   1 
ATOM 1939 C CA  . ALA C 2 91  ? -1.50900  5.62464   16.33950  1.000 637.53539 ? 91  ALA A CA  1 
ATOM 1940 C C   . ALA C 2 91  ? -2.32600  4.34364   16.34950  1.000 637.53539 ? 91  ALA A C   1 
ATOM 1941 O O   . ALA C 2 91  ? -2.01700  3.39964   17.08350  1.000 637.53539 ? 91  ALA A O   1 
ATOM 1942 C CB  . ALA C 2 91  ? -0.12700  5.38364   15.72750  1.000 637.53539 ? 91  ALA A CB  1 
ATOM 1943 N N   . GLU C 2 92  ? -3.37600  4.32564   15.53750  1.000 606.13654 ? 92  GLU A N   1 
ATOM 1944 C CA  . GLU C 2 92  ? -4.25800  3.17264   15.43450  1.000 606.13654 ? 92  GLU A CA  1 
ATOM 1945 C C   . GLU C 2 92  ? -3.59000  2.10164   14.58350  1.000 606.13654 ? 92  GLU A C   1 
ATOM 1946 O O   . GLU C 2 92  ? -3.89200  1.97264   13.39250  1.000 606.13654 ? 92  GLU A O   1 
ATOM 1947 C CB  . GLU C 2 92  ? -5.59000  3.58664   14.81250  1.000 606.13654 ? 92  GLU A CB  1 
ATOM 1948 C CG  . GLU C 2 92  ? -6.45300  4.50664   15.66250  1.000 606.13654 ? 92  GLU A CG  1 
ATOM 1949 C CD  . GLU C 2 92  ? -6.06500  5.97064   15.57250  1.000 606.13654 ? 92  GLU A CD  1 
ATOM 1950 O OE1 . GLU C 2 92  ? -5.11800  6.30964   14.83150  1.000 606.13654 ? 92  GLU A OE1 1 
ATOM 1951 O OE2 . GLU C 2 92  ? -6.72400  6.78564   16.24350  1.000 606.13654 ? 92  GLU A OE2 1 
ATOM 1952 N N   . VAL C 2 93  ? -2.67400  1.34164   15.18250  1.000 560.77120 ? 93  VAL A N   1 
ATOM 1953 C CA  . VAL C 2 93  ? -2.00300  0.23364   14.50750  1.000 560.77120 ? 93  VAL A CA  1 
ATOM 1954 C C   . VAL C 2 93  ? -2.26900  -1.04236  15.29650  1.000 560.77120 ? 93  VAL A C   1 
ATOM 1955 O O   . VAL C 2 93  ? -2.60500  -0.98936  16.48650  1.000 560.77120 ? 93  VAL A O   1 
ATOM 1956 C CB  . VAL C 2 93  ? -0.48800  0.48964   14.29950  1.000 560.77120 ? 93  VAL A CB  1 
ATOM 1957 C CG1 . VAL C 2 93  ? -0.15200  1.95064   14.40950  1.000 560.77120 ? 93  VAL A CG1 1 
ATOM 1958 C CG2 . VAL C 2 93  ? 0.37900   -0.23536  15.32050  1.000 560.77120 ? 93  VAL A CG2 1 
ATOM 1959 N N   . VAL C 2 94  ? -2.16900  -2.17836  14.61250  1.000 557.60288 ? 94  VAL A N   1 
ATOM 1960 C CA  . VAL C 2 94  ? -2.35300  -3.49336  15.21250  1.000 557.60288 ? 94  VAL A CA  1 
ATOM 1961 C C   . VAL C 2 94  ? -1.02600  -3.94636  15.80850  1.000 557.60288 ? 94  VAL A C   1 
ATOM 1962 O O   . VAL C 2 94  ? 0.04600   -3.50136  15.38250  1.000 557.60288 ? 94  VAL A O   1 
ATOM 1963 C CB  . VAL C 2 94  ? -2.89900  -4.50136  14.18050  1.000 557.60288 ? 94  VAL A CB  1 
ATOM 1964 C CG1 . VAL C 2 94  ? -3.53800  -3.76236  13.01850  1.000 557.60288 ? 94  VAL A CG1 1 
ATOM 1965 C CG2 . VAL C 2 94  ? -1.80600  -5.44336  13.62350  1.000 557.60288 ? 94  VAL A CG2 1 
ATOM 1966 N N   . PHE C 2 95  ? -1.10400  -4.78036  16.83850  1.000 531.81986 ? 95  PHE A N   1 
ATOM 1967 C CA  . PHE C 2 95  ? 0.07300   -5.39736  17.42750  1.000 531.81986 ? 95  PHE A CA  1 
ATOM 1968 C C   . PHE C 2 95  ? -0.34100  -6.75636  17.96550  1.000 531.81986 ? 95  PHE A C   1 
ATOM 1969 O O   . PHE C 2 95  ? -1.42800  -6.91336  18.52750  1.000 531.81986 ? 95  PHE A O   1 
ATOM 1970 C CB  . PHE C 2 95  ? 0.69200   -4.51836  18.52450  1.000 531.81986 ? 95  PHE A CB  1 
ATOM 1971 C CG  . PHE C 2 95  ? -0.14300  -4.40536  19.76850  1.000 531.81986 ? 95  PHE A CG  1 
ATOM 1972 C CD1 . PHE C 2 95  ? -1.24500  -3.56536  19.80150  1.000 531.81986 ? 95  PHE A CD1 1 
ATOM 1973 C CD2 . PHE C 2 95  ? 0.18600   -5.11936  20.91050  1.000 531.81986 ? 95  PHE A CD2 1 
ATOM 1974 C CE1 . PHE C 2 95  ? -2.01500  -3.45536  20.93350  1.000 531.81986 ? 95  PHE A CE1 1 
ATOM 1975 C CE2 . PHE C 2 95  ? -0.58200  -5.00936  22.05350  1.000 531.81986 ? 95  PHE A CE2 1 
ATOM 1976 C CZ  . PHE C 2 95  ? -1.68400  -4.17336  22.06250  1.000 531.81986 ? 95  PHE A CZ  1 
ATOM 1977 N N   . THR C 2 96  ? 0.52200   -7.74236  17.76050  1.000 522.83749 ? 96  THR A N   1 
ATOM 1978 C CA  . THR C 2 96  ? 0.24500   -9.11336  18.16150  1.000 522.83749 ? 96  THR A CA  1 
ATOM 1979 C C   . THR C 2 96  ? 1.37500   -9.62236  19.04450  1.000 522.83749 ? 96  THR A C   1 
ATOM 1980 O O   . THR C 2 96  ? 2.54400   -9.28936  18.81650  1.000 522.83749 ? 96  THR A O   1 
ATOM 1981 C CB  . THR C 2 96  ? 0.06700   -10.01736 16.93950  1.000 522.83749 ? 96  THR A CB  1 
ATOM 1982 O OG1 . THR C 2 96  ? 0.24600   -9.24836  15.74350  1.000 522.83749 ? 96  THR A OG1 1 
ATOM 1983 C CG2 . THR C 2 96  ? -1.32900  -10.63736 16.93450  1.000 522.83749 ? 96  THR A CG2 1 
ATOM 1984 N N   . ALA C 2 97  ? 1.01900   -10.40636 20.06250  1.000 606.64489 ? 97  ALA A N   1 
ATOM 1985 C CA  . ALA C 2 97  ? 1.98200   -10.97736 20.99250  1.000 606.64489 ? 97  ALA A CA  1 
ATOM 1986 C C   . ALA C 2 97  ? 1.39000   -12.21936 21.64450  1.000 606.64489 ? 97  ALA A C   1 
ATOM 1987 O O   . ALA C 2 97  ? 0.19900   -12.50636 21.49250  1.000 606.64489 ? 97  ALA A O   1 
ATOM 1988 C CB  . ALA C 2 97  ? 2.39100   -9.96736  22.07450  1.000 606.64489 ? 97  ALA A CB  1 
ATOM 1989 N N   . ASN C 2 98  ? 2.25500   -12.95936 22.35050  1.000 631.63000 ? 98  ASN A N   1 
ATOM 1990 C CA  . ASN C 2 98  ? 1.88900   -14.01136 23.30950  1.000 631.63000 ? 98  ASN A CA  1 
ATOM 1991 C C   . ASN C 2 98  ? 1.07600   -15.14036 22.66550  1.000 631.63000 ? 98  ASN A C   1 
ATOM 1992 O O   . ASN C 2 98  ? -0.09900  -15.36036 22.97350  1.000 631.63000 ? 98  ASN A O   1 
ATOM 1993 C CB  . ASN C 2 98  ? 1.15100   -13.41336 24.51350  1.000 631.63000 ? 98  ASN A CB  1 
ATOM 1994 C CG  . ASN C 2 98  ? 1.86600   -13.68336 25.82450  1.000 631.63000 ? 98  ASN A CG  1 
ATOM 1995 O OD1 . ASN C 2 98  ? 2.33400   -14.79536 26.06950  1.000 631.63000 ? 98  ASN A OD1 1 
ATOM 1996 N ND2 . ASN C 2 98  ? 1.97400   -12.66036 26.66250  1.000 631.63000 ? 98  ASN A ND2 1 
ATOM 1997 N N   . ASP C 2 99  ? 1.73200   -15.84736 21.74450  1.000 705.63694 ? 99  ASP A N   1 
ATOM 1998 C CA  . ASP C 2 99  ? 1.14700   -17.07336 21.21850  1.000 705.63694 ? 99  ASP A CA  1 
ATOM 1999 C C   . ASP C 2 99  ? 1.48500   -18.26936 22.10050  1.000 705.63694 ? 99  ASP A C   1 
ATOM 2000 O O   . ASP C 2 99  ? 0.61800   -19.09936 22.39350  1.000 705.63694 ? 99  ASP A O   1 
ATOM 2001 C CB  . ASP C 2 99  ? 1.61300   -17.30236 19.77950  1.000 705.63694 ? 99  ASP A CB  1 
ATOM 2002 C CG  . ASP C 2 99  ? 3.11600   -17.15636 19.61850  1.000 705.63694 ? 99  ASP A CG  1 
ATOM 2003 O OD1 . ASP C 2 99  ? 3.55000   -16.16436 19.00150  1.000 705.63694 ? 99  ASP A OD1 1 
ATOM 2004 O OD2 . ASP C 2 99  ? 3.86800   -18.02836 20.10050  1.000 705.63694 ? 99  ASP A OD2 1 
ATOM 2005 N N   . SER C 2 100 ? 2.74300   -18.38836 22.51750  1.000 656.74530 ? 100 SER A N   1 
ATOM 2006 C CA  . SER C 2 100 ? 3.15700   -19.48436 23.38350  1.000 656.74530 ? 100 SER A CA  1 
ATOM 2007 C C   . SER C 2 100 ? 4.15600   -19.00536 24.42750  1.000 656.74530 ? 100 SER A C   1 
ATOM 2008 O O   . SER C 2 100 ? 5.14600   -19.68536 24.71550  1.000 656.74530 ? 100 SER A O   1 
ATOM 2009 C CB  . SER C 2 100 ? 3.74100   -20.63936 22.57050  1.000 656.74530 ? 100 SER A CB  1 
ATOM 2010 O OG  . SER C 2 100 ? 2.73500   -21.29536 21.81450  1.000 656.74530 ? 100 SER A OG  1 
ATOM 2011 N N   . GLY C 2 101 ? 3.92000   -17.83336 25.01050  1.000 702.92626 ? 101 GLY A N   1 
ATOM 2012 C CA  . GLY C 2 101 ? 4.75100   -17.36036 26.09350  1.000 702.92626 ? 101 GLY A CA  1 
ATOM 2013 C C   . GLY C 2 101 ? 5.24400   -15.93636 25.92450  1.000 702.92626 ? 101 GLY A C   1 
ATOM 2014 O O   . GLY C 2 101 ? 5.46900   -15.45736 24.80850  1.000 702.92626 ? 101 GLY A O   1 
ATOM 2015 N N   . PRO C 2 102 ? 5.43200   -15.23436 27.04450  1.000 782.97393 ? 102 PRO A N   1 
ATOM 2016 C CA  . PRO C 2 102 ? 5.79200   -13.81136 26.98250  1.000 782.97393 ? 102 PRO A CA  1 
ATOM 2017 C C   . PRO C 2 102 ? 7.29500   -13.59936 26.85850  1.000 782.97393 ? 102 PRO A C   1 
ATOM 2018 O O   . PRO C 2 102 ? 8.09900   -14.35636 27.40850  1.000 782.97393 ? 102 PRO A O   1 
ATOM 2019 C CB  . PRO C 2 102 ? 5.26300   -13.26136 28.31250  1.000 782.97393 ? 102 PRO A CB  1 
ATOM 2020 C CG  . PRO C 2 102 ? 5.37600   -14.42136 29.25350  1.000 782.97393 ? 102 PRO A CG  1 
ATOM 2021 C CD  . PRO C 2 102 ? 5.20000   -15.68436 28.43050  1.000 782.97393 ? 102 PRO A CD  1 
ATOM 2022 N N   . ARG C 2 103 ? 7.67100   -12.56036 26.11950  1.000 914.87584 ? 103 ARG A N   1 
ATOM 2023 C CA  . ARG C 2 103 ? 9.05600   -12.12436 26.00750  1.000 914.87584 ? 103 ARG A CA  1 
ATOM 2024 C C   . ARG C 2 103 ? 9.17500   -10.66936 26.45150  1.000 914.87584 ? 103 ARG A C   1 
ATOM 2025 O O   . ARG C 2 103 ? 8.19700   -10.03536 26.85650  1.000 914.87584 ? 103 ARG A O   1 
ATOM 2026 C CB  . ARG C 2 103 ? 9.57800   -12.29836 24.57650  1.000 914.87584 ? 103 ARG A CB  1 
ATOM 2027 C CG  . ARG C 2 103 ? 9.60500   -13.73936 24.07950  1.000 914.87584 ? 103 ARG A CG  1 
ATOM 2028 C CD  . ARG C 2 103 ? 10.51800  -14.62936 24.92150  1.000 914.87584 ? 103 ARG A CD  1 
ATOM 2029 N NE  . ARG C 2 103 ? 10.48400  -16.01836 24.46650  1.000 914.87584 ? 103 ARG A NE  1 
ATOM 2030 C CZ  . ARG C 2 103 ? 10.91800  -17.05836 25.17350  1.000 914.87584 ? 103 ARG A CZ  1 
ATOM 2031 N NH1 . ARG C 2 103 ? 11.43400  -16.88236 26.38250  1.000 914.87584 ? 103 ARG A NH1 1 
ATOM 2032 N NH2 . ARG C 2 103 ? 10.83900  -18.28036 24.66450  1.000 914.87584 ? 103 ARG A NH2 1 
ATOM 2033 N N   . ARG C 2 104 ? 10.39300  -10.13836 26.35950  1.000 882.22332 ? 104 ARG A N   1 
ATOM 2034 C CA  . ARG C 2 104 ? 10.71600  -8.79536  26.83650  1.000 882.22332 ? 104 ARG A CA  1 
ATOM 2035 C C   . ARG C 2 104 ? 11.06100  -7.88636  25.66250  1.000 882.22332 ? 104 ARG A C   1 
ATOM 2036 O O   . ARG C 2 104 ? 12.21400  -7.84036  25.22250  1.000 882.22332 ? 104 ARG A O   1 
ATOM 2037 C CB  . ARG C 2 104 ? 11.86700  -8.82736  27.83950  1.000 882.22332 ? 104 ARG A CB  1 
ATOM 2038 C CG  . ARG C 2 104 ? 12.00900  -7.53336  28.62250  1.000 882.22332 ? 104 ARG A CG  1 
ATOM 2039 C CD  . ARG C 2 104 ? 13.15900  -6.66136  28.10750  1.000 882.22332 ? 104 ARG A CD  1 
ATOM 2040 N NE  . ARG C 2 104 ? 14.46400  -7.29136  28.26950  1.000 882.22332 ? 104 ARG A NE  1 
ATOM 2041 C CZ  . ARG C 2 104 ? 15.53100  -6.98336  27.54150  1.000 882.22332 ? 104 ARG A CZ  1 
ATOM 2042 N NH1 . ARG C 2 104 ? 15.44500  -6.05836  26.59650  1.000 882.22332 ? 104 ARG A NH1 1 
ATOM 2043 N NH2 . ARG C 2 104 ? 16.68400  -7.60036  27.75350  1.000 882.22332 ? 104 ARG A NH2 1 
ATOM 2044 N N   . TYR C 2 105 ? 10.05900  -7.19836  25.12750  1.000 913.38494 ? 105 TYR A N   1 
ATOM 2045 C CA  . TYR C 2 105 ? 10.27100  -5.99936  24.32750  1.000 913.38494 ? 105 TYR A CA  1 
ATOM 2046 C C   . TYR C 2 105 ? 9.11600   -5.03336  24.55550  1.000 913.38494 ? 105 TYR A C   1 
ATOM 2047 O O   . TYR C 2 105 ? 7.95700   -5.35436  24.27950  1.000 913.38494 ? 105 TYR A O   1 
ATOM 2048 C CB  . TYR C 2 105 ? 10.48300  -6.20736  22.78750  1.000 913.38494 ? 105 TYR A CB  1 
ATOM 2049 C CG  . TYR C 2 105 ? 10.61700  -7.55936  22.03950  1.000 913.38494 ? 105 TYR A CG  1 
ATOM 2050 C CD1 . TYR C 2 105 ? 10.19900  -8.80036  22.53950  1.000 913.38494 ? 105 TYR A CD1 1 
ATOM 2051 C CD2 . TYR C 2 105 ? 11.21800  -7.55436  20.78350  1.000 913.38494 ? 105 TYR A CD2 1 
ATOM 2052 C CE1 . TYR C 2 105 ? 10.37600  -9.96136  21.81450  1.000 913.38494 ? 105 TYR A CE1 1 
ATOM 2053 C CE2 . TYR C 2 105 ? 11.38800  -8.70636  20.05850  1.000 913.38494 ? 105 TYR A CE2 1 
ATOM 2054 C CZ  . TYR C 2 105 ? 10.96800  -9.90336  20.57350  1.000 913.38494 ? 105 TYR A CZ  1 
ATOM 2055 O OH  . TYR C 2 105 ? 11.14900  -11.04536 19.83050  1.000 913.38494 ? 105 TYR A OH  1 
ATOM 2056 N N   . THR C 2 106 ? 9.44800   -3.84836  25.06250  1.000 850.12875 ? 106 THR A N   1 
ATOM 2057 C CA  . THR C 2 106 ? 8.47600   -2.81836  25.40650  1.000 850.12875 ? 106 THR A CA  1 
ATOM 2058 C C   . THR C 2 106 ? 8.56000   -1.72836  24.33950  1.000 850.12875 ? 106 THR A C   1 
ATOM 2059 O O   . THR C 2 106 ? 9.61800   -1.53836  23.72850  1.000 850.12875 ? 106 THR A O   1 
ATOM 2060 C CB  . THR C 2 106 ? 8.76100   -2.27736  26.81950  1.000 850.12875 ? 106 THR A CB  1 
ATOM 2061 O OG1 . THR C 2 106 ? 8.89900   -3.38036  27.72850  1.000 850.12875 ? 106 THR A OG1 1 
ATOM 2062 C CG2 . THR C 2 106 ? 7.63000   -1.39436  27.35050  1.000 850.12875 ? 106 THR A CG2 1 
ATOM 2063 N N   . ILE C 2 107 ? 7.45200   -1.02536  24.10550  1.000 960.75156 ? 107 ILE A N   1 
ATOM 2064 C CA  . ILE C 2 107 ? 7.34400   -0.09936  22.98450  1.000 960.75156 ? 107 ILE A CA  1 
ATOM 2065 C C   . ILE C 2 107 ? 8.04500   1.21864   23.29250  1.000 960.75156 ? 107 ILE A C   1 
ATOM 2066 O O   . ILE C 2 107 ? 7.44000   2.14464   23.84450  1.000 960.75156 ? 107 ILE A O   1 
ATOM 2067 C CB  . ILE C 2 107 ? 5.86900   0.14764   22.62450  1.000 960.75156 ? 107 ILE A CB  1 
ATOM 2068 C CG1 . ILE C 2 107 ? 5.07300   -1.16136  22.66550  1.000 960.75156 ? 107 ILE A CG1 1 
ATOM 2069 C CG2 . ILE C 2 107 ? 5.75500   0.81564   21.26050  1.000 960.75156 ? 107 ILE A CG2 1 
ATOM 2070 C CD1 . ILE C 2 107 ? 5.42800   -2.14136  21.57250  1.000 960.75156 ? 107 ILE A CD1 1 
ATOM 2071 N N   . ALA C 2 108 ? 9.32200   1.31164   22.93150  1.000 747.66570 ? 108 ALA A N   1 
ATOM 2072 C CA  . ALA C 2 108 ? 10.05400  2.56864   22.93450  1.000 747.66570 ? 108 ALA A CA  1 
ATOM 2073 C C   . ALA C 2 108 ? 9.89600   3.21264   21.56850  1.000 747.66570 ? 108 ALA A C   1 
ATOM 2074 O O   . ALA C 2 108 ? 10.47000  2.74664   20.58150  1.000 747.66570 ? 108 ALA A O   1 
ATOM 2075 C CB  . ALA C 2 108 ? 11.53600  2.35464   23.24850  1.000 747.66570 ? 108 ALA A CB  1 
ATOM 2076 N N   . ALA C 2 109 ? 9.12200   4.28564   21.50950  1.000 497.18242 ? 109 ALA A N   1 
ATOM 2077 C CA  . ALA C 2 109 ? 8.61300   4.78264   20.24250  1.000 497.18242 ? 109 ALA A CA  1 
ATOM 2078 C C   . ALA C 2 109 ? 9.66400   5.60664   19.51350  1.000 497.18242 ? 109 ALA A C   1 
ATOM 2079 O O   . ALA C 2 109 ? 10.58400  6.14464   20.13950  1.000 497.18242 ? 109 ALA A O   1 
ATOM 2080 C CB  . ALA C 2 109 ? 7.34600   5.61164   20.44250  1.000 497.18242 ? 109 ALA A CB  1 
ATOM 2081 N N   . LEU C 2 110 ? 9.52900   5.67864   18.18750  1.000 444.40972 ? 110 LEU A N   1 
ATOM 2082 C CA  . LEU C 2 110 ? 10.34700  6.55764   17.35750  1.000 444.40972 ? 110 LEU A CA  1 
ATOM 2083 C C   . LEU C 2 110 ? 10.02300  7.99964   17.68250  1.000 444.40972 ? 110 LEU A C   1 
ATOM 2084 O O   . LEU C 2 110 ? 8.88700   8.44964   17.50750  1.000 444.40972 ? 110 LEU A O   1 
ATOM 2085 C CB  . LEU C 2 110 ? 10.10900  6.30864   15.87150  1.000 444.40972 ? 110 LEU A CB  1 
ATOM 2086 C CG  . LEU C 2 110 ? 10.62300  7.39064   14.90850  1.000 444.40972 ? 110 LEU A CG  1 
ATOM 2087 C CD1 . LEU C 2 110 ? 12.14000  7.47064   14.91450  1.000 444.40972 ? 110 LEU A CD1 1 
ATOM 2088 C CD2 . LEU C 2 110 ? 10.10300  7.19064   13.49050  1.000 444.40972 ? 110 LEU A CD2 1 
ATOM 2089 N N   . LEU C 2 111 ? 11.01800  8.73264   18.14750  1.000 419.47680 ? 111 LEU A N   1 
ATOM 2090 C CA  . LEU C 2 111 ? 10.86500  10.16864  18.24050  1.000 419.47680 ? 111 LEU A CA  1 
ATOM 2091 C C   . LEU C 2 111 ? 10.85000  10.76964  16.84750  1.000 419.47680 ? 111 LEU A C   1 
ATOM 2092 O O   . LEU C 2 111 ? 11.90000  11.06464  16.27550  1.000 419.47680 ? 111 LEU A O   1 
ATOM 2093 C CB  . LEU C 2 111 ? 11.97600  10.78564  19.07750  1.000 419.47680 ? 111 LEU A CB  1 
ATOM 2094 C CG  . LEU C 2 111 ? 11.63800  10.83564  20.55950  1.000 419.47680 ? 111 LEU A CG  1 
ATOM 2095 C CD1 . LEU C 2 111 ? 12.68700  11.63464  21.27050  1.000 419.47680 ? 111 LEU A CD1 1 
ATOM 2096 C CD2 . LEU C 2 111 ? 10.26400  11.44064  20.74750  1.000 419.47680 ? 111 LEU A CD2 1 
ATOM 2097 N N   . SER C 2 112 ? 9.65700   10.95064  16.31050  1.000 426.86452 ? 112 SER A N   1 
ATOM 2098 C CA  . SER C 2 112 ? 9.42900   11.87264  15.22050  1.000 426.86452 ? 112 SER A CA  1 
ATOM 2099 C C   . SER C 2 112 ? 8.40200   12.84964  15.74550  1.000 426.86452 ? 112 SER A C   1 
ATOM 2100 O O   . SER C 2 112 ? 7.65500   12.52064  16.68150  1.000 426.86452 ? 112 SER A O   1 
ATOM 2101 C CB  . SER C 2 112 ? 8.92500   11.16664  13.95050  1.000 426.86452 ? 112 SER A CB  1 
ATOM 2102 O OG  . SER C 2 112 ? 8.47000   9.86764   14.24950  1.000 426.86452 ? 112 SER A OG  1 
ATOM 2103 N N   . PRO C 2 113 ? 8.36900   14.08364  15.22650  1.000 361.67593 ? 113 PRO A N   1 
ATOM 2104 C CA  . PRO C 2 113 ? 7.39300   15.05964  15.73250  1.000 361.67593 ? 113 PRO A CA  1 
ATOM 2105 C C   . PRO C 2 113 ? 5.95000   14.65864  15.49450  1.000 361.67593 ? 113 PRO A C   1 
ATOM 2106 O O   . PRO C 2 113 ? 5.20000   14.48864  16.45950  1.000 361.67593 ? 113 PRO A O   1 
ATOM 2107 C CB  . PRO C 2 113 ? 7.76400   16.34064  14.97550  1.000 361.67593 ? 113 PRO A CB  1 
ATOM 2108 C CG  . PRO C 2 113 ? 9.21100   16.15864  14.62950  1.000 361.67593 ? 113 PRO A CG  1 
ATOM 2109 C CD  . PRO C 2 113 ? 9.36200   14.71464  14.33550  1.000 361.67593 ? 113 PRO A CD  1 
ATOM 2110 N N   . TYR C 2 114 ? 5.55900   14.42464  14.25150  1.000 299.81700 ? 114 TYR A N   1 
ATOM 2111 C CA  . TYR C 2 114 ? 4.17400   14.11764  13.94450  1.000 299.81700 ? 114 TYR A CA  1 
ATOM 2112 C C   . TYR C 2 114 ? 3.83000   12.64864  14.12650  1.000 299.81700 ? 114 TYR A C   1 
ATOM 2113 O O   . TYR C 2 114 ? 2.64900   12.31364  14.19450  1.000 299.81700 ? 114 TYR A O   1 
ATOM 2114 C CB  . TYR C 2 114 ? 3.85100   14.54564  12.51150  1.000 299.81700 ? 114 TYR A CB  1 
ATOM 2115 C CG  . TYR C 2 114 ? 3.85200   16.03464  12.32050  1.000 299.81700 ? 114 TYR A CG  1 
ATOM 2116 C CD1 . TYR C 2 114 ? 4.99800   16.69664  11.91750  1.000 299.81700 ? 114 TYR A CD1 1 
ATOM 2117 C CD2 . TYR C 2 114 ? 2.69500   16.77264  12.51450  1.000 299.81700 ? 114 TYR A CD2 1 
ATOM 2118 C CE1 . TYR C 2 114 ? 4.99900   18.05864  11.73750  1.000 299.81700 ? 114 TYR A CE1 1 
ATOM 2119 C CE2 . TYR C 2 114 ? 2.68000   18.12664  12.33150  1.000 299.81700 ? 114 TYR A CE2 1 
ATOM 2120 C CZ  . TYR C 2 114 ? 3.84300   18.76564  11.94450  1.000 299.81700 ? 114 TYR A CZ  1 
ATOM 2121 O OH  . TYR C 2 114 ? 3.83900   20.12264  11.76250  1.000 299.81700 ? 114 TYR A OH  1 
ATOM 2122 N N   . SER C 2 115 ? 4.81500   11.76264  14.22250  1.000 450.09755 ? 115 SER A N   1 
ATOM 2123 C CA  . SER C 2 115 ? 4.48800   10.34764  14.17650  1.000 450.09755 ? 115 SER A CA  1 
ATOM 2124 C C   . SER C 2 115 ? 5.44000   9.55764   15.05450  1.000 450.09755 ? 115 SER A C   1 
ATOM 2125 O O   . SER C 2 115 ? 6.39100   10.09864  15.61950  1.000 450.09755 ? 115 SER A O   1 
ATOM 2126 C CB  . SER C 2 115 ? 4.53700   9.81364   12.74450  1.000 450.09755 ? 115 SER A CB  1 
ATOM 2127 O OG  . SER C 2 115 ? 4.98400   10.80864  11.84850  1.000 450.09755 ? 115 SER A OG  1 
ATOM 2128 N N   . TYR C 2 116 ? 5.17000   8.25864   15.14850  1.000 527.05702 ? 116 TYR A N   1 
ATOM 2129 C CA  . TYR C 2 116 ? 6.07900   7.34564   15.82150  1.000 527.05702 ? 116 TYR A CA  1 
ATOM 2130 C C   . TYR C 2 116 ? 5.93000   5.93764   15.26250  1.000 527.05702 ? 116 TYR A C   1 
ATOM 2131 O O   . TYR C 2 116 ? 4.81600   5.42764   15.09950  1.000 527.05702 ? 116 TYR A O   1 
ATOM 2132 C CB  . TYR C 2 116 ? 5.86600   7.35064   17.34750  1.000 527.05702 ? 116 TYR A CB  1 
ATOM 2133 C CG  . TYR C 2 116 ? 4.53600   6.81764   17.82050  1.000 527.05702 ? 116 TYR A CG  1 
ATOM 2134 C CD1 . TYR C 2 116 ? 4.40400   5.51364   18.28250  1.000 527.05702 ? 116 TYR A CD1 1 
ATOM 2135 C CD2 . TYR C 2 116 ? 3.41600   7.63264   17.82650  1.000 527.05702 ? 116 TYR A CD2 1 
ATOM 2136 C CE1 . TYR C 2 116 ? 3.18100   5.03364   18.71650  1.000 527.05702 ? 116 TYR A CE1 1 
ATOM 2137 C CE2 . TYR C 2 116 ? 2.19200   7.16764   18.25450  1.000 527.05702 ? 116 TYR A CE2 1 
ATOM 2138 C CZ  . TYR C 2 116 ? 2.07800   5.86764   18.70050  1.000 527.05702 ? 116 TYR A CZ  1 
ATOM 2139 O OH  . TYR C 2 116 ? 0.85900   5.39864   19.13250  1.000 527.05702 ? 116 TYR A OH  1 
ATOM 2140 N N   . SER C 2 117 ? 7.06700   5.33864   14.93750  1.000 484.88882 ? 117 SER A N   1 
ATOM 2141 C CA  . SER C 2 117 ? 7.24100   3.89864   14.90350  1.000 484.88882 ? 117 SER A CA  1 
ATOM 2142 C C   . SER C 2 117 ? 7.90300   3.51864   16.21750  1.000 484.88882 ? 117 SER A C   1 
ATOM 2143 O O   . SER C 2 117 ? 7.90600   4.30164   17.16250  1.000 484.88882 ? 117 SER A O   1 
ATOM 2144 C CB  . SER C 2 117 ? 8.05800   3.44964   13.69250  1.000 484.88882 ? 117 SER A CB  1 
ATOM 2145 O OG  . SER C 2 117 ? 9.37700   3.97264   13.73450  1.000 484.88882 ? 117 SER A OG  1 
ATOM 2146 N N   . THR C 2 118 ? 8.41000   2.29764   16.31050  1.000 636.66984 ? 118 THR A N   1 
ATOM 2147 C CA  . THR C 2 118 ? 9.03600   1.83164   17.53950  1.000 636.66984 ? 118 THR A CA  1 
ATOM 2148 C C   . THR C 2 118 ? 10.53500  1.67664   17.32850  1.000 636.66984 ? 118 THR A C   1 
ATOM 2149 O O   . THR C 2 118 ? 10.96400  0.94864   16.42750  1.000 636.66984 ? 118 THR A O   1 
ATOM 2150 C CB  . THR C 2 118 ? 8.41800   0.50864   17.98450  1.000 636.66984 ? 118 THR A CB  1 
ATOM 2151 O OG1 . THR C 2 118 ? 7.01800   0.69864   18.21050  1.000 636.66984 ? 118 THR A OG1 1 
ATOM 2152 C CG2 . THR C 2 118 ? 9.05800   0.03464   19.27250  1.000 636.66984 ? 118 THR A CG2 1 
ATOM 2153 N N   . THR C 2 119 ? 11.32700  2.36464   18.15150  1.000 631.72133 ? 119 THR A N   1 
ATOM 2154 C CA  . THR C 2 119 ? 12.78200  2.34664   18.03850  1.000 631.72133 ? 119 THR A CA  1 
ATOM 2155 C C   . THR C 2 119 ? 13.44300  1.77164   19.28450  1.000 631.72133 ? 119 THR A C   1 
ATOM 2156 O O   . THR C 2 119 ? 13.31100  2.32864   20.37950  1.000 631.72133 ? 119 THR A O   1 
ATOM 2157 C CB  . THR C 2 119 ? 13.32500  3.74864   17.77450  1.000 631.72133 ? 119 THR A CB  1 
ATOM 2158 O OG1 . THR C 2 119 ? 12.76100  4.67264   18.71750  1.000 631.72133 ? 119 THR A OG1 1 
ATOM 2159 C CG2 . THR C 2 119 ? 13.02500  4.16064   16.35550  1.000 631.72133 ? 119 THR A CG2 1 
ATOM 2160 N N   . ALA C 2 120 ? 14.19600  0.68664   19.09250  1.000 773.32512 ? 120 ALA A N   1 
ATOM 2161 C CA  . ALA C 2 120 ? 14.93700  0.01664   20.15150  1.000 773.32512 ? 120 ALA A CA  1 
ATOM 2162 C C   . ALA C 2 120 ? 15.99800  -0.88736  19.53950  1.000 773.32512 ? 120 ALA A C   1 
ATOM 2163 O O   . ALA C 2 120 ? 15.80000  -1.45036  18.45950  1.000 773.32512 ? 120 ALA A O   1 
ATOM 2164 C CB  . ALA C 2 120 ? 14.00900  -0.81036  21.05150  1.000 773.32512 ? 120 ALA A CB  1 
ATOM 2165 N N   . VAL C 2 121 ? 17.12300  -1.01336  20.23250  1.000 785.12989 ? 121 VAL A N   1 
ATOM 2166 C CA  . VAL C 2 121 ? 18.15600  -1.99636  19.92550  1.000 785.12989 ? 121 VAL A CA  1 
ATOM 2167 C C   . VAL C 2 121 ? 17.64400  -3.35736  20.39150  1.000 785.12989 ? 121 VAL A C   1 
ATOM 2168 O O   . VAL C 2 121 ? 17.43500  -3.57936  21.58850  1.000 785.12989 ? 121 VAL A O   1 
ATOM 2169 C CB  . VAL C 2 121 ? 19.48800  -1.63336  20.59450  1.000 785.12989 ? 121 VAL A CB  1 
ATOM 2170 C CG1 . VAL C 2 121 ? 20.46200  -2.79336  20.50450  1.000 785.12989 ? 121 VAL A CG1 1 
ATOM 2171 C CG2 . VAL C 2 121 ? 20.07900  -0.37936  19.95650  1.000 785.12989 ? 121 VAL A CG2 1 
ATOM 2172 N N   . VAL C 2 122 ? 17.45200  -4.27436  19.44650  1.000 899.17442 ? 122 VAL A N   1 
ATOM 2173 C CA  . VAL C 2 122 ? 16.69900  -5.50236  19.69750  1.000 899.17442 ? 122 VAL A CA  1 
ATOM 2174 C C   . VAL C 2 122 ? 17.55700  -6.49836  20.46950  1.000 899.17442 ? 122 VAL A C   1 
ATOM 2175 O O   . VAL C 2 122 ? 18.75800  -6.63936  20.20850  1.000 899.17442 ? 122 VAL A O   1 
ATOM 2176 C CB  . VAL C 2 122 ? 16.19500  -6.11036  18.37750  1.000 899.17442 ? 122 VAL A CB  1 
ATOM 2177 C CG1 . VAL C 2 122 ? 14.69100  -5.88236  18.23550  1.000 899.17442 ? 122 VAL A CG1 1 
ATOM 2178 C CG2 . VAL C 2 122 ? 16.97100  -5.55436  17.17450  1.000 899.17442 ? 122 VAL A CG2 1 
ATOM 2179 N N   . THR C 2 123 ? 16.94100  -7.18236  21.43450  1.000 885.15171 ? 123 THR A N   1 
ATOM 2180 C CA  . THR C 2 123 ? 17.59600  -8.20436  22.23850  1.000 885.15171 ? 123 THR A CA  1 
ATOM 2181 C C   . THR C 2 123 ? 16.92500  -9.55936  22.02550  1.000 885.15171 ? 123 THR A C   1 
ATOM 2182 O O   . THR C 2 123 ? 15.72100  -9.64136  21.76250  1.000 885.15171 ? 123 THR A O   1 
ATOM 2183 C CB  . THR C 2 123 ? 17.57900  -7.83436  23.73350  1.000 885.15171 ? 123 THR A CB  1 
ATOM 2184 O OG1 . THR C 2 123 ? 16.22800  -7.81336  24.21150  1.000 885.15171 ? 123 THR A OG1 1 
ATOM 2185 C CG2 . THR C 2 123 ? 18.20800  -6.46336  23.95450  1.000 885.15171 ? 123 THR A CG2 1 
ATOM 2186 N N   . ASN C 2 124 ? 17.73100  -10.63136 22.13750  0.500 625.30395 ? 124 ASN A N   1 
ATOM 2187 C CA  . ASN C 2 124 ? 17.33400  -12.02036 21.93850  0.500 625.30395 ? 124 ASN A CA  1 
ATOM 2188 C C   . ASN C 2 124 ? 16.47000  -12.52436 23.10150  0.500 625.30395 ? 124 ASN A C   1 
ATOM 2189 O O   . ASN C 2 124 ? 16.41300  -11.88236 24.15450  0.500 625.30395 ? 124 ASN A O   1 
ATOM 2190 C CB  . ASN C 2 124 ? 18.58800  -12.89536 21.73550  0.500 625.30395 ? 124 ASN A CB  1 
ATOM 2191 C CG  . ASN C 2 124 ? 19.58900  -12.83436 22.89850  0.500 625.30395 ? 124 ASN A CG  1 
ATOM 2192 O OD1 . ASN C 2 124 ? 19.24800  -12.97036 24.07150  0.500 625.30395 ? 124 ASN A OD1 1 
ATOM 2193 N ND2 . ASN C 2 124 ? 20.85300  -12.63136 22.55050  0.500 625.30395 ? 124 ASN A ND2 1 
ATOM 2194 N N   . PRO C 2 125 ? 15.74800  -13.63936 22.92250  0.500 542.54369 ? 125 PRO A N   1 
ATOM 2195 C CA  . PRO C 2 125 ? 15.05300  -14.26036 24.06650  0.500 542.54369 ? 125 PRO A CA  1 
ATOM 2196 C C   . PRO C 2 125 ? 16.02200  -14.73436 25.14350  0.500 542.54369 ? 125 PRO A C   1 
ATOM 2197 O O   . PRO C 2 125 ? 16.79400  -15.67636 24.93950  0.500 542.54369 ? 125 PRO A O   1 
ATOM 2198 C CB  . PRO C 2 125 ? 14.29700  -15.43236 23.43050  0.500 542.54369 ? 125 PRO A CB  1 
ATOM 2199 C CG  . PRO C 2 125 ? 14.08400  -15.01436 22.02350  0.500 542.54369 ? 125 PRO A CG  1 
ATOM 2200 C CD  . PRO C 2 125 ? 15.25900  -14.17536 21.63550  0.500 542.54369 ? 125 PRO A CD  1 
ATOM 2201 N N   . LYS C 2 126 ? 15.93800  -14.09036 26.31050  0.500 386.60826 ? 126 LYS A N   1 
ATOM 2202 C CA  . LYS C 2 126 ? 16.95300  -14.19336 27.35450  0.500 386.60826 ? 126 LYS A CA  1 
ATOM 2203 C C   . LYS C 2 126 ? 16.23900  -13.99636 28.68450  0.500 386.60826 ? 126 LYS A C   1 
ATOM 2204 O O   . LYS C 2 126 ? 15.39600  -13.10536 28.80350  0.500 386.60826 ? 126 LYS A O   1 
ATOM 2205 C CB  . LYS C 2 126 ? 18.03100  -13.11936 27.10350  0.500 386.60826 ? 126 LYS A CB  1 
ATOM 2206 C CG  . LYS C 2 126 ? 19.34100  -13.00636 27.93950  0.500 386.60826 ? 126 LYS A CG  1 
ATOM 2207 C CD  . LYS C 2 126 ? 19.64200  -14.04836 28.99950  0.500 386.60826 ? 126 LYS A CD  1 
ATOM 2208 C CE  . LYS C 2 126 ? 20.94300  -13.74536 29.70050  0.500 386.60826 ? 126 LYS A CE  1 
ATOM 2209 N NZ  . LYS C 2 126 ? 20.75800  -13.69536 31.17050  0.500 386.60826 ? 126 LYS A NZ  1 
ATOM 2210 N N   . GLU C 2 127 ? 16.56200  -14.81736 29.67650  0.500 344.22963 ? 127 GLU A N   1 
ATOM 2211 C CA  . GLU C 2 127 ? 16.00400  -14.61836 31.00150  0.500 344.22963 ? 127 GLU A CA  1 
ATOM 2212 C C   . GLU C 2 127 ? 17.08400  -14.09836 31.94350  0.500 344.22963 ? 127 GLU A C   1 
ATOM 2213 O O   . GLU C 2 127 ? 16.93600  -13.03936 32.54850  0.500 344.22963 ? 127 GLU A O   1 
ATOM 2214 C CB  . GLU C 2 127 ? 15.39600  -15.91636 31.55050  0.500 344.22963 ? 127 GLU A CB  1 
ATOM 2215 C CG  . GLU C 2 127 ? 14.39600  -15.68836 32.68750  0.500 344.22963 ? 127 GLU A CG  1 
ATOM 2216 C CD  . GLU C 2 127 ? 15.05600  -15.68436 34.05850  0.500 344.22963 ? 127 GLU A CD  1 
ATOM 2217 O OE1 . GLU C 2 127 ? 16.15800  -16.25236 34.18550  0.500 344.22963 ? 127 GLU A OE1 1 
ATOM 2218 O OE2 . GLU C 2 127 ? 14.47800  -15.12136 35.01250  0.500 344.22963 ? 127 GLU A OE2 1 
ATOM 2219 O OXT . GLU C 2 127 ? 18.13800  -14.71236 32.11350  0.500 344.22963 ? 127 GLU A OXT 1 
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