data_8Z7B
# 
_entry.id   8Z7B 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.399 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8Z7B         pdb_00008z7b 10.2210/pdb8z7b/pdb 
WWPDB D_1300047147 ?            ?                   
EMDB  EMD-39811    ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-02-05 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8Z7B 
_pdbx_database_status.recvd_initial_deposition_date   2024-04-19 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBC 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        
;Cryo-EM structure of SARS-CoV-2 S trimer in the early fusion intermediate conformation (E-FIC) (focused refinement of NTD-SD1-RBD-ACE2)
;
_pdbx_database_related.db_id          EMD-39811 
_pdbx_database_related.content_type   'associated EM volume' 
# 
loop_
_pdbx_contact_author.id 
_pdbx_contact_author.email 
_pdbx_contact_author.name_first 
_pdbx_contact_author.name_last 
_pdbx_contact_author.name_mi 
_pdbx_contact_author.role 
_pdbx_contact_author.identifier_ORCID 
3 llsun@fudan.edu.cn      Lei   Sun   ? 'principal investigator/group leader' 0000-0001-8741-0202 
4 lul@fudan.edu.cn        Lu    Lu    ? 'principal investigator/group leader' 0000-0002-2255-0391 
5 shibojiang@fudan.edu.cn Shibo Jiang ? 'principal investigator/group leader' 0000-0001-8283-7135 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Liu, Z.'  1 ? 
'Xing, L.' 2 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
;Cryo-EM structure of SARS-CoV-2 S trimer in the early fusion intermediate conformation (E-FIC) (focused refinement of NTD-SD1-RBD-ACE2)
;
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Liu, Z.'  1 ? 
primary 'Xing, L.' 2 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Angiotensin-converting enzyme 2' 72989.047  1 3.4.17.23,3.4.17.- ? ? ? 
2 polymer     man 'Spike glycoprotein' 142535.641 2 ?                  ? ? ? 
3 branched    man '2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose' 424.401    7 ? ? ? ? 
4 branched    man 
'beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose' 586.542    1 
?                  ? ? ? 
5 non-polymer syn 2-acetamido-2-deoxy-beta-D-glucopyranose 221.208    7 ?                  ? ? ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
1 
;Angiotensin-converting enzyme homolog,ACEH,Angiotensin-converting enzyme-related carboxypeptidase,ACE-related carboxypeptidase,Metalloprotease MPROT15
;
2 'S glycoprotein,E2,Peplomer protein' 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;MSSSSWLLLSLVAVTAAQSTIEEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLA
QMYPLQEIQNLTVKLQLQALQQNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNE
RLWAWESWRSEVGKQLRPLYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHL
HAYVRAKLMNAYPSYISPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGL
PNMTQGFWENSMLTDPGNVQKAVCHPTAWDLGKGDFRILMCTKVTMDDFLTAHHEMGHIQYDMAYAAQPFLLRNGANEGF
HEAVGEIMSLSAATPKHLKSIGLLSPDFQEDNETEINFLLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEM
KREIVGVVEPVPHDETYCDPASLFHVSNDYSFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISNSTEAGQKLFNMLRL
GKSEPWTLALENVVGAKNMNVRPLLNYFEPLFTWLKDQNKNSFVGWSTDWSPYADLEVLFQGPHHHHHHHH
;
;MSSSSWLLLSLVAVTAAQSTIEEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLA
QMYPLQEIQNLTVKLQLQALQQNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNE
RLWAWESWRSEVGKQLRPLYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHL
HAYVRAKLMNAYPSYISPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGL
PNMTQGFWENSMLTDPGNVQKAVCHPTAWDLGKGDFRILMCTKVTMDDFLTAHHEMGHIQYDMAYAAQPFLLRNGANEGF
HEAVGEIMSLSAATPKHLKSIGLLSPDFQEDNETEINFLLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEM
KREIVGVVEPVPHDETYCDPASLFHVSNDYSFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISNSTEAGQKLFNMLRL
GKSEPWTLALENVVGAKNMNVRPLLNYFEPLFTWLKDQNKNSFVGWSTDWSPYADLEVLFQGPHHHHHHHH
;
D   ? 
2 'polypeptide(L)' no no 
;MFVFLVLLPLVSSQCVNLTTRTQLPPAYTNSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAIHVSGTNGTKRFD
NPVLPFNDGVYFASTEKSNIIRGWIFGTTLDSKTQSLLIVNNATNVVIKVCEFQFCNDPFLGVYYHKNNKSWMESEFRVY
SSANNCTFEYVSQPFLMDLEGKQGNFKNLREFVFKNIDGYFKIYSKHTPINLVRDLPQGFSALEPLVDLPIGINITRFQT
LLALHRSYLTPGDSSSGWTAGAAAYYVGYLQPRTFLLKYNENGTITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNFRV
QPTESIVRFPNITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSF
VIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPC
NGVEGFNCYFPLQSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCGPKKSTNLVKNKCVNFNFNGLTGTGVLTESNKKFL
PFQQFGRDIADTTDAVRDPQTLEILDITPCSFGGVSVITPGTNTSNQVAVLYQGVNCTEVPVAIHADQLTPTWRVYSTGS
NVFQTRAGCLIGAEHVNNSYECDIPIGAGICASYQTQTNSPRRARSVASQSIIAYTMSLGAENSVAYSNNSIAIPTNFTI
SVTTEILPVSMTKTSVDCTMYICGDSTECSNLLLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKDFGGF
NFSQILPDPSKPSKRSFIEDLLFNKVTLADAGFIKQYGDCLGDIAARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAG
TITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALN
TLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRV
DFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDGKAHFPREGVFVSNGTHWFVTQRNFYEPQIITTDNT
FVSGNCDVVIGIVNNTVYDPLQPELDSFKEELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDL
QELGKYEQGSGYIPEAPRDGQAYVRKDGEWVFLSTFLSGLEVLFQGPGGWSHPQFEKGGGSGGGSGGSAWSHPQFEKGGS
HHHHHHHH
;
;MFVFLVLLPLVSSQCVNLTTRTQLPPAYTNSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAIHVSGTNGTKRFD
NPVLPFNDGVYFASTEKSNIIRGWIFGTTLDSKTQSLLIVNNATNVVIKVCEFQFCNDPFLGVYYHKNNKSWMESEFRVY
SSANNCTFEYVSQPFLMDLEGKQGNFKNLREFVFKNIDGYFKIYSKHTPINLVRDLPQGFSALEPLVDLPIGINITRFQT
LLALHRSYLTPGDSSSGWTAGAAAYYVGYLQPRTFLLKYNENGTITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNFRV
QPTESIVRFPNITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSF
VIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPC
NGVEGFNCYFPLQSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCGPKKSTNLVKNKCVNFNFNGLTGTGVLTESNKKFL
PFQQFGRDIADTTDAVRDPQTLEILDITPCSFGGVSVITPGTNTSNQVAVLYQGVNCTEVPVAIHADQLTPTWRVYSTGS
NVFQTRAGCLIGAEHVNNSYECDIPIGAGICASYQTQTNSPRRARSVASQSIIAYTMSLGAENSVAYSNNSIAIPTNFTI
SVTTEILPVSMTKTSVDCTMYICGDSTECSNLLLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKDFGGF
NFSQILPDPSKPSKRSFIEDLLFNKVTLADAGFIKQYGDCLGDIAARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAG
TITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALN
TLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRV
DFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDGKAHFPREGVFVSNGTHWFVTQRNFYEPQIITTDNT
FVSGNCDVVIGIVNNTVYDPLQPELDSFKEELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDL
QELGKYEQGSGYIPEAPRDGQAYVRKDGEWVFLSTFLSGLEVLFQGPGGWSHPQFEKGGGSGGGSGGSAWSHPQFEKGGS
HHHHHHHH
;
C,A ? 
# 
_pdbx_entity_nonpoly.entity_id   5 
_pdbx_entity_nonpoly.name        2-acetamido-2-deoxy-beta-D-glucopyranose 
_pdbx_entity_nonpoly.comp_id     NAG 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1    MET n 
1 2    SER n 
1 3    SER n 
1 4    SER n 
1 5    SER n 
1 6    TRP n 
1 7    LEU n 
1 8    LEU n 
1 9    LEU n 
1 10   SER n 
1 11   LEU n 
1 12   VAL n 
1 13   ALA n 
1 14   VAL n 
1 15   THR n 
1 16   ALA n 
1 17   ALA n 
1 18   GLN n 
1 19   SER n 
1 20   THR n 
1 21   ILE n 
1 22   GLU n 
1 23   GLU n 
1 24   GLN n 
1 25   ALA n 
1 26   LYS n 
1 27   THR n 
1 28   PHE n 
1 29   LEU n 
1 30   ASP n 
1 31   LYS n 
1 32   PHE n 
1 33   ASN n 
1 34   HIS n 
1 35   GLU n 
1 36   ALA n 
1 37   GLU n 
1 38   ASP n 
1 39   LEU n 
1 40   PHE n 
1 41   TYR n 
1 42   GLN n 
1 43   SER n 
1 44   SER n 
1 45   LEU n 
1 46   ALA n 
1 47   SER n 
1 48   TRP n 
1 49   ASN n 
1 50   TYR n 
1 51   ASN n 
1 52   THR n 
1 53   ASN n 
1 54   ILE n 
1 55   THR n 
1 56   GLU n 
1 57   GLU n 
1 58   ASN n 
1 59   VAL n 
1 60   GLN n 
1 61   ASN n 
1 62   MET n 
1 63   ASN n 
1 64   ASN n 
1 65   ALA n 
1 66   GLY n 
1 67   ASP n 
1 68   LYS n 
1 69   TRP n 
1 70   SER n 
1 71   ALA n 
1 72   PHE n 
1 73   LEU n 
1 74   LYS n 
1 75   GLU n 
1 76   GLN n 
1 77   SER n 
1 78   THR n 
1 79   LEU n 
1 80   ALA n 
1 81   GLN n 
1 82   MET n 
1 83   TYR n 
1 84   PRO n 
1 85   LEU n 
1 86   GLN n 
1 87   GLU n 
1 88   ILE n 
1 89   GLN n 
1 90   ASN n 
1 91   LEU n 
1 92   THR n 
1 93   VAL n 
1 94   LYS n 
1 95   LEU n 
1 96   GLN n 
1 97   LEU n 
1 98   GLN n 
1 99   ALA n 
1 100  LEU n 
1 101  GLN n 
1 102  GLN n 
1 103  ASN n 
1 104  GLY n 
1 105  SER n 
1 106  SER n 
1 107  VAL n 
1 108  LEU n 
1 109  SER n 
1 110  GLU n 
1 111  ASP n 
1 112  LYS n 
1 113  SER n 
1 114  LYS n 
1 115  ARG n 
1 116  LEU n 
1 117  ASN n 
1 118  THR n 
1 119  ILE n 
1 120  LEU n 
1 121  ASN n 
1 122  THR n 
1 123  MET n 
1 124  SER n 
1 125  THR n 
1 126  ILE n 
1 127  TYR n 
1 128  SER n 
1 129  THR n 
1 130  GLY n 
1 131  LYS n 
1 132  VAL n 
1 133  CYS n 
1 134  ASN n 
1 135  PRO n 
1 136  ASP n 
1 137  ASN n 
1 138  PRO n 
1 139  GLN n 
1 140  GLU n 
1 141  CYS n 
1 142  LEU n 
1 143  LEU n 
1 144  LEU n 
1 145  GLU n 
1 146  PRO n 
1 147  GLY n 
1 148  LEU n 
1 149  ASN n 
1 150  GLU n 
1 151  ILE n 
1 152  MET n 
1 153  ALA n 
1 154  ASN n 
1 155  SER n 
1 156  LEU n 
1 157  ASP n 
1 158  TYR n 
1 159  ASN n 
1 160  GLU n 
1 161  ARG n 
1 162  LEU n 
1 163  TRP n 
1 164  ALA n 
1 165  TRP n 
1 166  GLU n 
1 167  SER n 
1 168  TRP n 
1 169  ARG n 
1 170  SER n 
1 171  GLU n 
1 172  VAL n 
1 173  GLY n 
1 174  LYS n 
1 175  GLN n 
1 176  LEU n 
1 177  ARG n 
1 178  PRO n 
1 179  LEU n 
1 180  TYR n 
1 181  GLU n 
1 182  GLU n 
1 183  TYR n 
1 184  VAL n 
1 185  VAL n 
1 186  LEU n 
1 187  LYS n 
1 188  ASN n 
1 189  GLU n 
1 190  MET n 
1 191  ALA n 
1 192  ARG n 
1 193  ALA n 
1 194  ASN n 
1 195  HIS n 
1 196  TYR n 
1 197  GLU n 
1 198  ASP n 
1 199  TYR n 
1 200  GLY n 
1 201  ASP n 
1 202  TYR n 
1 203  TRP n 
1 204  ARG n 
1 205  GLY n 
1 206  ASP n 
1 207  TYR n 
1 208  GLU n 
1 209  VAL n 
1 210  ASN n 
1 211  GLY n 
1 212  VAL n 
1 213  ASP n 
1 214  GLY n 
1 215  TYR n 
1 216  ASP n 
1 217  TYR n 
1 218  SER n 
1 219  ARG n 
1 220  GLY n 
1 221  GLN n 
1 222  LEU n 
1 223  ILE n 
1 224  GLU n 
1 225  ASP n 
1 226  VAL n 
1 227  GLU n 
1 228  HIS n 
1 229  THR n 
1 230  PHE n 
1 231  GLU n 
1 232  GLU n 
1 233  ILE n 
1 234  LYS n 
1 235  PRO n 
1 236  LEU n 
1 237  TYR n 
1 238  GLU n 
1 239  HIS n 
1 240  LEU n 
1 241  HIS n 
1 242  ALA n 
1 243  TYR n 
1 244  VAL n 
1 245  ARG n 
1 246  ALA n 
1 247  LYS n 
1 248  LEU n 
1 249  MET n 
1 250  ASN n 
1 251  ALA n 
1 252  TYR n 
1 253  PRO n 
1 254  SER n 
1 255  TYR n 
1 256  ILE n 
1 257  SER n 
1 258  PRO n 
1 259  ILE n 
1 260  GLY n 
1 261  CYS n 
1 262  LEU n 
1 263  PRO n 
1 264  ALA n 
1 265  HIS n 
1 266  LEU n 
1 267  LEU n 
1 268  GLY n 
1 269  ASP n 
1 270  MET n 
1 271  TRP n 
1 272  GLY n 
1 273  ARG n 
1 274  PHE n 
1 275  TRP n 
1 276  THR n 
1 277  ASN n 
1 278  LEU n 
1 279  TYR n 
1 280  SER n 
1 281  LEU n 
1 282  THR n 
1 283  VAL n 
1 284  PRO n 
1 285  PHE n 
1 286  GLY n 
1 287  GLN n 
1 288  LYS n 
1 289  PRO n 
1 290  ASN n 
1 291  ILE n 
1 292  ASP n 
1 293  VAL n 
1 294  THR n 
1 295  ASP n 
1 296  ALA n 
1 297  MET n 
1 298  VAL n 
1 299  ASP n 
1 300  GLN n 
1 301  ALA n 
1 302  TRP n 
1 303  ASP n 
1 304  ALA n 
1 305  GLN n 
1 306  ARG n 
1 307  ILE n 
1 308  PHE n 
1 309  LYS n 
1 310  GLU n 
1 311  ALA n 
1 312  GLU n 
1 313  LYS n 
1 314  PHE n 
1 315  PHE n 
1 316  VAL n 
1 317  SER n 
1 318  VAL n 
1 319  GLY n 
1 320  LEU n 
1 321  PRO n 
1 322  ASN n 
1 323  MET n 
1 324  THR n 
1 325  GLN n 
1 326  GLY n 
1 327  PHE n 
1 328  TRP n 
1 329  GLU n 
1 330  ASN n 
1 331  SER n 
1 332  MET n 
1 333  LEU n 
1 334  THR n 
1 335  ASP n 
1 336  PRO n 
1 337  GLY n 
1 338  ASN n 
1 339  VAL n 
1 340  GLN n 
1 341  LYS n 
1 342  ALA n 
1 343  VAL n 
1 344  CYS n 
1 345  HIS n 
1 346  PRO n 
1 347  THR n 
1 348  ALA n 
1 349  TRP n 
1 350  ASP n 
1 351  LEU n 
1 352  GLY n 
1 353  LYS n 
1 354  GLY n 
1 355  ASP n 
1 356  PHE n 
1 357  ARG n 
1 358  ILE n 
1 359  LEU n 
1 360  MET n 
1 361  CYS n 
1 362  THR n 
1 363  LYS n 
1 364  VAL n 
1 365  THR n 
1 366  MET n 
1 367  ASP n 
1 368  ASP n 
1 369  PHE n 
1 370  LEU n 
1 371  THR n 
1 372  ALA n 
1 373  HIS n 
1 374  HIS n 
1 375  GLU n 
1 376  MET n 
1 377  GLY n 
1 378  HIS n 
1 379  ILE n 
1 380  GLN n 
1 381  TYR n 
1 382  ASP n 
1 383  MET n 
1 384  ALA n 
1 385  TYR n 
1 386  ALA n 
1 387  ALA n 
1 388  GLN n 
1 389  PRO n 
1 390  PHE n 
1 391  LEU n 
1 392  LEU n 
1 393  ARG n 
1 394  ASN n 
1 395  GLY n 
1 396  ALA n 
1 397  ASN n 
1 398  GLU n 
1 399  GLY n 
1 400  PHE n 
1 401  HIS n 
1 402  GLU n 
1 403  ALA n 
1 404  VAL n 
1 405  GLY n 
1 406  GLU n 
1 407  ILE n 
1 408  MET n 
1 409  SER n 
1 410  LEU n 
1 411  SER n 
1 412  ALA n 
1 413  ALA n 
1 414  THR n 
1 415  PRO n 
1 416  LYS n 
1 417  HIS n 
1 418  LEU n 
1 419  LYS n 
1 420  SER n 
1 421  ILE n 
1 422  GLY n 
1 423  LEU n 
1 424  LEU n 
1 425  SER n 
1 426  PRO n 
1 427  ASP n 
1 428  PHE n 
1 429  GLN n 
1 430  GLU n 
1 431  ASP n 
1 432  ASN n 
1 433  GLU n 
1 434  THR n 
1 435  GLU n 
1 436  ILE n 
1 437  ASN n 
1 438  PHE n 
1 439  LEU n 
1 440  LEU n 
1 441  LYS n 
1 442  GLN n 
1 443  ALA n 
1 444  LEU n 
1 445  THR n 
1 446  ILE n 
1 447  VAL n 
1 448  GLY n 
1 449  THR n 
1 450  LEU n 
1 451  PRO n 
1 452  PHE n 
1 453  THR n 
1 454  TYR n 
1 455  MET n 
1 456  LEU n 
1 457  GLU n 
1 458  LYS n 
1 459  TRP n 
1 460  ARG n 
1 461  TRP n 
1 462  MET n 
1 463  VAL n 
1 464  PHE n 
1 465  LYS n 
1 466  GLY n 
1 467  GLU n 
1 468  ILE n 
1 469  PRO n 
1 470  LYS n 
1 471  ASP n 
1 472  GLN n 
1 473  TRP n 
1 474  MET n 
1 475  LYS n 
1 476  LYS n 
1 477  TRP n 
1 478  TRP n 
1 479  GLU n 
1 480  MET n 
1 481  LYS n 
1 482  ARG n 
1 483  GLU n 
1 484  ILE n 
1 485  VAL n 
1 486  GLY n 
1 487  VAL n 
1 488  VAL n 
1 489  GLU n 
1 490  PRO n 
1 491  VAL n 
1 492  PRO n 
1 493  HIS n 
1 494  ASP n 
1 495  GLU n 
1 496  THR n 
1 497  TYR n 
1 498  CYS n 
1 499  ASP n 
1 500  PRO n 
1 501  ALA n 
1 502  SER n 
1 503  LEU n 
1 504  PHE n 
1 505  HIS n 
1 506  VAL n 
1 507  SER n 
1 508  ASN n 
1 509  ASP n 
1 510  TYR n 
1 511  SER n 
1 512  PHE n 
1 513  ILE n 
1 514  ARG n 
1 515  TYR n 
1 516  TYR n 
1 517  THR n 
1 518  ARG n 
1 519  THR n 
1 520  LEU n 
1 521  TYR n 
1 522  GLN n 
1 523  PHE n 
1 524  GLN n 
1 525  PHE n 
1 526  GLN n 
1 527  GLU n 
1 528  ALA n 
1 529  LEU n 
1 530  CYS n 
1 531  GLN n 
1 532  ALA n 
1 533  ALA n 
1 534  LYS n 
1 535  HIS n 
1 536  GLU n 
1 537  GLY n 
1 538  PRO n 
1 539  LEU n 
1 540  HIS n 
1 541  LYS n 
1 542  CYS n 
1 543  ASP n 
1 544  ILE n 
1 545  SER n 
1 546  ASN n 
1 547  SER n 
1 548  THR n 
1 549  GLU n 
1 550  ALA n 
1 551  GLY n 
1 552  GLN n 
1 553  LYS n 
1 554  LEU n 
1 555  PHE n 
1 556  ASN n 
1 557  MET n 
1 558  LEU n 
1 559  ARG n 
1 560  LEU n 
1 561  GLY n 
1 562  LYS n 
1 563  SER n 
1 564  GLU n 
1 565  PRO n 
1 566  TRP n 
1 567  THR n 
1 568  LEU n 
1 569  ALA n 
1 570  LEU n 
1 571  GLU n 
1 572  ASN n 
1 573  VAL n 
1 574  VAL n 
1 575  GLY n 
1 576  ALA n 
1 577  LYS n 
1 578  ASN n 
1 579  MET n 
1 580  ASN n 
1 581  VAL n 
1 582  ARG n 
1 583  PRO n 
1 584  LEU n 
1 585  LEU n 
1 586  ASN n 
1 587  TYR n 
1 588  PHE n 
1 589  GLU n 
1 590  PRO n 
1 591  LEU n 
1 592  PHE n 
1 593  THR n 
1 594  TRP n 
1 595  LEU n 
1 596  LYS n 
1 597  ASP n 
1 598  GLN n 
1 599  ASN n 
1 600  LYS n 
1 601  ASN n 
1 602  SER n 
1 603  PHE n 
1 604  VAL n 
1 605  GLY n 
1 606  TRP n 
1 607  SER n 
1 608  THR n 
1 609  ASP n 
1 610  TRP n 
1 611  SER n 
1 612  PRO n 
1 613  TYR n 
1 614  ALA n 
1 615  ASP n 
1 616  LEU n 
1 617  GLU n 
1 618  VAL n 
1 619  LEU n 
1 620  PHE n 
1 621  GLN n 
1 622  GLY n 
1 623  PRO n 
1 624  HIS n 
1 625  HIS n 
1 626  HIS n 
1 627  HIS n 
1 628  HIS n 
1 629  HIS n 
1 630  HIS n 
1 631  HIS n 
2 1    MET n 
2 2    PHE n 
2 3    VAL n 
2 4    PHE n 
2 5    LEU n 
2 6    VAL n 
2 7    LEU n 
2 8    LEU n 
2 9    PRO n 
2 10   LEU n 
2 11   VAL n 
2 12   SER n 
2 13   SER n 
2 14   GLN n 
2 15   CYS n 
2 16   VAL n 
2 17   ASN n 
2 18   LEU n 
2 19   THR n 
2 20   THR n 
2 21   ARG n 
2 22   THR n 
2 23   GLN n 
2 24   LEU n 
2 25   PRO n 
2 26   PRO n 
2 27   ALA n 
2 28   TYR n 
2 29   THR n 
2 30   ASN n 
2 31   SER n 
2 32   PHE n 
2 33   THR n 
2 34   ARG n 
2 35   GLY n 
2 36   VAL n 
2 37   TYR n 
2 38   TYR n 
2 39   PRO n 
2 40   ASP n 
2 41   LYS n 
2 42   VAL n 
2 43   PHE n 
2 44   ARG n 
2 45   SER n 
2 46   SER n 
2 47   VAL n 
2 48   LEU n 
2 49   HIS n 
2 50   SER n 
2 51   THR n 
2 52   GLN n 
2 53   ASP n 
2 54   LEU n 
2 55   PHE n 
2 56   LEU n 
2 57   PRO n 
2 58   PHE n 
2 59   PHE n 
2 60   SER n 
2 61   ASN n 
2 62   VAL n 
2 63   THR n 
2 64   TRP n 
2 65   PHE n 
2 66   HIS n 
2 67   ALA n 
2 68   ILE n 
2 69   HIS n 
2 70   VAL n 
2 71   SER n 
2 72   GLY n 
2 73   THR n 
2 74   ASN n 
2 75   GLY n 
2 76   THR n 
2 77   LYS n 
2 78   ARG n 
2 79   PHE n 
2 80   ASP n 
2 81   ASN n 
2 82   PRO n 
2 83   VAL n 
2 84   LEU n 
2 85   PRO n 
2 86   PHE n 
2 87   ASN n 
2 88   ASP n 
2 89   GLY n 
2 90   VAL n 
2 91   TYR n 
2 92   PHE n 
2 93   ALA n 
2 94   SER n 
2 95   THR n 
2 96   GLU n 
2 97   LYS n 
2 98   SER n 
2 99   ASN n 
2 100  ILE n 
2 101  ILE n 
2 102  ARG n 
2 103  GLY n 
2 104  TRP n 
2 105  ILE n 
2 106  PHE n 
2 107  GLY n 
2 108  THR n 
2 109  THR n 
2 110  LEU n 
2 111  ASP n 
2 112  SER n 
2 113  LYS n 
2 114  THR n 
2 115  GLN n 
2 116  SER n 
2 117  LEU n 
2 118  LEU n 
2 119  ILE n 
2 120  VAL n 
2 121  ASN n 
2 122  ASN n 
2 123  ALA n 
2 124  THR n 
2 125  ASN n 
2 126  VAL n 
2 127  VAL n 
2 128  ILE n 
2 129  LYS n 
2 130  VAL n 
2 131  CYS n 
2 132  GLU n 
2 133  PHE n 
2 134  GLN n 
2 135  PHE n 
2 136  CYS n 
2 137  ASN n 
2 138  ASP n 
2 139  PRO n 
2 140  PHE n 
2 141  LEU n 
2 142  GLY n 
2 143  VAL n 
2 144  TYR n 
2 145  TYR n 
2 146  HIS n 
2 147  LYS n 
2 148  ASN n 
2 149  ASN n 
2 150  LYS n 
2 151  SER n 
2 152  TRP n 
2 153  MET n 
2 154  GLU n 
2 155  SER n 
2 156  GLU n 
2 157  PHE n 
2 158  ARG n 
2 159  VAL n 
2 160  TYR n 
2 161  SER n 
2 162  SER n 
2 163  ALA n 
2 164  ASN n 
2 165  ASN n 
2 166  CYS n 
2 167  THR n 
2 168  PHE n 
2 169  GLU n 
2 170  TYR n 
2 171  VAL n 
2 172  SER n 
2 173  GLN n 
2 174  PRO n 
2 175  PHE n 
2 176  LEU n 
2 177  MET n 
2 178  ASP n 
2 179  LEU n 
2 180  GLU n 
2 181  GLY n 
2 182  LYS n 
2 183  GLN n 
2 184  GLY n 
2 185  ASN n 
2 186  PHE n 
2 187  LYS n 
2 188  ASN n 
2 189  LEU n 
2 190  ARG n 
2 191  GLU n 
2 192  PHE n 
2 193  VAL n 
2 194  PHE n 
2 195  LYS n 
2 196  ASN n 
2 197  ILE n 
2 198  ASP n 
2 199  GLY n 
2 200  TYR n 
2 201  PHE n 
2 202  LYS n 
2 203  ILE n 
2 204  TYR n 
2 205  SER n 
2 206  LYS n 
2 207  HIS n 
2 208  THR n 
2 209  PRO n 
2 210  ILE n 
2 211  ASN n 
2 212  LEU n 
2 213  VAL n 
2 214  ARG n 
2 215  ASP n 
2 216  LEU n 
2 217  PRO n 
2 218  GLN n 
2 219  GLY n 
2 220  PHE n 
2 221  SER n 
2 222  ALA n 
2 223  LEU n 
2 224  GLU n 
2 225  PRO n 
2 226  LEU n 
2 227  VAL n 
2 228  ASP n 
2 229  LEU n 
2 230  PRO n 
2 231  ILE n 
2 232  GLY n 
2 233  ILE n 
2 234  ASN n 
2 235  ILE n 
2 236  THR n 
2 237  ARG n 
2 238  PHE n 
2 239  GLN n 
2 240  THR n 
2 241  LEU n 
2 242  LEU n 
2 243  ALA n 
2 244  LEU n 
2 245  HIS n 
2 246  ARG n 
2 247  SER n 
2 248  TYR n 
2 249  LEU n 
2 250  THR n 
2 251  PRO n 
2 252  GLY n 
2 253  ASP n 
2 254  SER n 
2 255  SER n 
2 256  SER n 
2 257  GLY n 
2 258  TRP n 
2 259  THR n 
2 260  ALA n 
2 261  GLY n 
2 262  ALA n 
2 263  ALA n 
2 264  ALA n 
2 265  TYR n 
2 266  TYR n 
2 267  VAL n 
2 268  GLY n 
2 269  TYR n 
2 270  LEU n 
2 271  GLN n 
2 272  PRO n 
2 273  ARG n 
2 274  THR n 
2 275  PHE n 
2 276  LEU n 
2 277  LEU n 
2 278  LYS n 
2 279  TYR n 
2 280  ASN n 
2 281  GLU n 
2 282  ASN n 
2 283  GLY n 
2 284  THR n 
2 285  ILE n 
2 286  THR n 
2 287  ASP n 
2 288  ALA n 
2 289  VAL n 
2 290  ASP n 
2 291  CYS n 
2 292  ALA n 
2 293  LEU n 
2 294  ASP n 
2 295  PRO n 
2 296  LEU n 
2 297  SER n 
2 298  GLU n 
2 299  THR n 
2 300  LYS n 
2 301  CYS n 
2 302  THR n 
2 303  LEU n 
2 304  LYS n 
2 305  SER n 
2 306  PHE n 
2 307  THR n 
2 308  VAL n 
2 309  GLU n 
2 310  LYS n 
2 311  GLY n 
2 312  ILE n 
2 313  TYR n 
2 314  GLN n 
2 315  THR n 
2 316  SER n 
2 317  ASN n 
2 318  PHE n 
2 319  ARG n 
2 320  VAL n 
2 321  GLN n 
2 322  PRO n 
2 323  THR n 
2 324  GLU n 
2 325  SER n 
2 326  ILE n 
2 327  VAL n 
2 328  ARG n 
2 329  PHE n 
2 330  PRO n 
2 331  ASN n 
2 332  ILE n 
2 333  THR n 
2 334  ASN n 
2 335  LEU n 
2 336  CYS n 
2 337  PRO n 
2 338  PHE n 
2 339  GLY n 
2 340  GLU n 
2 341  VAL n 
2 342  PHE n 
2 343  ASN n 
2 344  ALA n 
2 345  THR n 
2 346  ARG n 
2 347  PHE n 
2 348  ALA n 
2 349  SER n 
2 350  VAL n 
2 351  TYR n 
2 352  ALA n 
2 353  TRP n 
2 354  ASN n 
2 355  ARG n 
2 356  LYS n 
2 357  ARG n 
2 358  ILE n 
2 359  SER n 
2 360  ASN n 
2 361  CYS n 
2 362  VAL n 
2 363  ALA n 
2 364  ASP n 
2 365  TYR n 
2 366  SER n 
2 367  VAL n 
2 368  LEU n 
2 369  TYR n 
2 370  ASN n 
2 371  SER n 
2 372  ALA n 
2 373  SER n 
2 374  PHE n 
2 375  SER n 
2 376  THR n 
2 377  PHE n 
2 378  LYS n 
2 379  CYS n 
2 380  TYR n 
2 381  GLY n 
2 382  VAL n 
2 383  SER n 
2 384  PRO n 
2 385  THR n 
2 386  LYS n 
2 387  LEU n 
2 388  ASN n 
2 389  ASP n 
2 390  LEU n 
2 391  CYS n 
2 392  PHE n 
2 393  THR n 
2 394  ASN n 
2 395  VAL n 
2 396  TYR n 
2 397  ALA n 
2 398  ASP n 
2 399  SER n 
2 400  PHE n 
2 401  VAL n 
2 402  ILE n 
2 403  ARG n 
2 404  GLY n 
2 405  ASP n 
2 406  GLU n 
2 407  VAL n 
2 408  ARG n 
2 409  GLN n 
2 410  ILE n 
2 411  ALA n 
2 412  PRO n 
2 413  GLY n 
2 414  GLN n 
2 415  THR n 
2 416  GLY n 
2 417  LYS n 
2 418  ILE n 
2 419  ALA n 
2 420  ASP n 
2 421  TYR n 
2 422  ASN n 
2 423  TYR n 
2 424  LYS n 
2 425  LEU n 
2 426  PRO n 
2 427  ASP n 
2 428  ASP n 
2 429  PHE n 
2 430  THR n 
2 431  GLY n 
2 432  CYS n 
2 433  VAL n 
2 434  ILE n 
2 435  ALA n 
2 436  TRP n 
2 437  ASN n 
2 438  SER n 
2 439  ASN n 
2 440  ASN n 
2 441  LEU n 
2 442  ASP n 
2 443  SER n 
2 444  LYS n 
2 445  VAL n 
2 446  GLY n 
2 447  GLY n 
2 448  ASN n 
2 449  TYR n 
2 450  ASN n 
2 451  TYR n 
2 452  LEU n 
2 453  TYR n 
2 454  ARG n 
2 455  LEU n 
2 456  PHE n 
2 457  ARG n 
2 458  LYS n 
2 459  SER n 
2 460  ASN n 
2 461  LEU n 
2 462  LYS n 
2 463  PRO n 
2 464  PHE n 
2 465  GLU n 
2 466  ARG n 
2 467  ASP n 
2 468  ILE n 
2 469  SER n 
2 470  THR n 
2 471  GLU n 
2 472  ILE n 
2 473  TYR n 
2 474  GLN n 
2 475  ALA n 
2 476  GLY n 
2 477  SER n 
2 478  THR n 
2 479  PRO n 
2 480  CYS n 
2 481  ASN n 
2 482  GLY n 
2 483  VAL n 
2 484  GLU n 
2 485  GLY n 
2 486  PHE n 
2 487  ASN n 
2 488  CYS n 
2 489  TYR n 
2 490  PHE n 
2 491  PRO n 
2 492  LEU n 
2 493  GLN n 
2 494  SER n 
2 495  TYR n 
2 496  GLY n 
2 497  PHE n 
2 498  GLN n 
2 499  PRO n 
2 500  THR n 
2 501  ASN n 
2 502  GLY n 
2 503  VAL n 
2 504  GLY n 
2 505  TYR n 
2 506  GLN n 
2 507  PRO n 
2 508  TYR n 
2 509  ARG n 
2 510  VAL n 
2 511  VAL n 
2 512  VAL n 
2 513  LEU n 
2 514  SER n 
2 515  PHE n 
2 516  GLU n 
2 517  LEU n 
2 518  LEU n 
2 519  HIS n 
2 520  ALA n 
2 521  PRO n 
2 522  ALA n 
2 523  THR n 
2 524  VAL n 
2 525  CYS n 
2 526  GLY n 
2 527  PRO n 
2 528  LYS n 
2 529  LYS n 
2 530  SER n 
2 531  THR n 
2 532  ASN n 
2 533  LEU n 
2 534  VAL n 
2 535  LYS n 
2 536  ASN n 
2 537  LYS n 
2 538  CYS n 
2 539  VAL n 
2 540  ASN n 
2 541  PHE n 
2 542  ASN n 
2 543  PHE n 
2 544  ASN n 
2 545  GLY n 
2 546  LEU n 
2 547  THR n 
2 548  GLY n 
2 549  THR n 
2 550  GLY n 
2 551  VAL n 
2 552  LEU n 
2 553  THR n 
2 554  GLU n 
2 555  SER n 
2 556  ASN n 
2 557  LYS n 
2 558  LYS n 
2 559  PHE n 
2 560  LEU n 
2 561  PRO n 
2 562  PHE n 
2 563  GLN n 
2 564  GLN n 
2 565  PHE n 
2 566  GLY n 
2 567  ARG n 
2 568  ASP n 
2 569  ILE n 
2 570  ALA n 
2 571  ASP n 
2 572  THR n 
2 573  THR n 
2 574  ASP n 
2 575  ALA n 
2 576  VAL n 
2 577  ARG n 
2 578  ASP n 
2 579  PRO n 
2 580  GLN n 
2 581  THR n 
2 582  LEU n 
2 583  GLU n 
2 584  ILE n 
2 585  LEU n 
2 586  ASP n 
2 587  ILE n 
2 588  THR n 
2 589  PRO n 
2 590  CYS n 
2 591  SER n 
2 592  PHE n 
2 593  GLY n 
2 594  GLY n 
2 595  VAL n 
2 596  SER n 
2 597  VAL n 
2 598  ILE n 
2 599  THR n 
2 600  PRO n 
2 601  GLY n 
2 602  THR n 
2 603  ASN n 
2 604  THR n 
2 605  SER n 
2 606  ASN n 
2 607  GLN n 
2 608  VAL n 
2 609  ALA n 
2 610  VAL n 
2 611  LEU n 
2 612  TYR n 
2 613  GLN n 
2 614  GLY n 
2 615  VAL n 
2 616  ASN n 
2 617  CYS n 
2 618  THR n 
2 619  GLU n 
2 620  VAL n 
2 621  PRO n 
2 622  VAL n 
2 623  ALA n 
2 624  ILE n 
2 625  HIS n 
2 626  ALA n 
2 627  ASP n 
2 628  GLN n 
2 629  LEU n 
2 630  THR n 
2 631  PRO n 
2 632  THR n 
2 633  TRP n 
2 634  ARG n 
2 635  VAL n 
2 636  TYR n 
2 637  SER n 
2 638  THR n 
2 639  GLY n 
2 640  SER n 
2 641  ASN n 
2 642  VAL n 
2 643  PHE n 
2 644  GLN n 
2 645  THR n 
2 646  ARG n 
2 647  ALA n 
2 648  GLY n 
2 649  CYS n 
2 650  LEU n 
2 651  ILE n 
2 652  GLY n 
2 653  ALA n 
2 654  GLU n 
2 655  HIS n 
2 656  VAL n 
2 657  ASN n 
2 658  ASN n 
2 659  SER n 
2 660  TYR n 
2 661  GLU n 
2 662  CYS n 
2 663  ASP n 
2 664  ILE n 
2 665  PRO n 
2 666  ILE n 
2 667  GLY n 
2 668  ALA n 
2 669  GLY n 
2 670  ILE n 
2 671  CYS n 
2 672  ALA n 
2 673  SER n 
2 674  TYR n 
2 675  GLN n 
2 676  THR n 
2 677  GLN n 
2 678  THR n 
2 679  ASN n 
2 680  SER n 
2 681  PRO n 
2 682  ARG n 
2 683  ARG n 
2 684  ALA n 
2 685  ARG n 
2 686  SER n 
2 687  VAL n 
2 688  ALA n 
2 689  SER n 
2 690  GLN n 
2 691  SER n 
2 692  ILE n 
2 693  ILE n 
2 694  ALA n 
2 695  TYR n 
2 696  THR n 
2 697  MET n 
2 698  SER n 
2 699  LEU n 
2 700  GLY n 
2 701  ALA n 
2 702  GLU n 
2 703  ASN n 
2 704  SER n 
2 705  VAL n 
2 706  ALA n 
2 707  TYR n 
2 708  SER n 
2 709  ASN n 
2 710  ASN n 
2 711  SER n 
2 712  ILE n 
2 713  ALA n 
2 714  ILE n 
2 715  PRO n 
2 716  THR n 
2 717  ASN n 
2 718  PHE n 
2 719  THR n 
2 720  ILE n 
2 721  SER n 
2 722  VAL n 
2 723  THR n 
2 724  THR n 
2 725  GLU n 
2 726  ILE n 
2 727  LEU n 
2 728  PRO n 
2 729  VAL n 
2 730  SER n 
2 731  MET n 
2 732  THR n 
2 733  LYS n 
2 734  THR n 
2 735  SER n 
2 736  VAL n 
2 737  ASP n 
2 738  CYS n 
2 739  THR n 
2 740  MET n 
2 741  TYR n 
2 742  ILE n 
2 743  CYS n 
2 744  GLY n 
2 745  ASP n 
2 746  SER n 
2 747  THR n 
2 748  GLU n 
2 749  CYS n 
2 750  SER n 
2 751  ASN n 
2 752  LEU n 
2 753  LEU n 
2 754  LEU n 
2 755  GLN n 
2 756  TYR n 
2 757  GLY n 
2 758  SER n 
2 759  PHE n 
2 760  CYS n 
2 761  THR n 
2 762  GLN n 
2 763  LEU n 
2 764  ASN n 
2 765  ARG n 
2 766  ALA n 
2 767  LEU n 
2 768  THR n 
2 769  GLY n 
2 770  ILE n 
2 771  ALA n 
2 772  VAL n 
2 773  GLU n 
2 774  GLN n 
2 775  ASP n 
2 776  LYS n 
2 777  ASN n 
2 778  THR n 
2 779  GLN n 
2 780  GLU n 
2 781  VAL n 
2 782  PHE n 
2 783  ALA n 
2 784  GLN n 
2 785  VAL n 
2 786  LYS n 
2 787  GLN n 
2 788  ILE n 
2 789  TYR n 
2 790  LYS n 
2 791  THR n 
2 792  PRO n 
2 793  PRO n 
2 794  ILE n 
2 795  LYS n 
2 796  ASP n 
2 797  PHE n 
2 798  GLY n 
2 799  GLY n 
2 800  PHE n 
2 801  ASN n 
2 802  PHE n 
2 803  SER n 
2 804  GLN n 
2 805  ILE n 
2 806  LEU n 
2 807  PRO n 
2 808  ASP n 
2 809  PRO n 
2 810  SER n 
2 811  LYS n 
2 812  PRO n 
2 813  SER n 
2 814  LYS n 
2 815  ARG n 
2 816  SER n 
2 817  PHE n 
2 818  ILE n 
2 819  GLU n 
2 820  ASP n 
2 821  LEU n 
2 822  LEU n 
2 823  PHE n 
2 824  ASN n 
2 825  LYS n 
2 826  VAL n 
2 827  THR n 
2 828  LEU n 
2 829  ALA n 
2 830  ASP n 
2 831  ALA n 
2 832  GLY n 
2 833  PHE n 
2 834  ILE n 
2 835  LYS n 
2 836  GLN n 
2 837  TYR n 
2 838  GLY n 
2 839  ASP n 
2 840  CYS n 
2 841  LEU n 
2 842  GLY n 
2 843  ASP n 
2 844  ILE n 
2 845  ALA n 
2 846  ALA n 
2 847  ARG n 
2 848  ASP n 
2 849  LEU n 
2 850  ILE n 
2 851  CYS n 
2 852  ALA n 
2 853  GLN n 
2 854  LYS n 
2 855  PHE n 
2 856  ASN n 
2 857  GLY n 
2 858  LEU n 
2 859  THR n 
2 860  VAL n 
2 861  LEU n 
2 862  PRO n 
2 863  PRO n 
2 864  LEU n 
2 865  LEU n 
2 866  THR n 
2 867  ASP n 
2 868  GLU n 
2 869  MET n 
2 870  ILE n 
2 871  ALA n 
2 872  GLN n 
2 873  TYR n 
2 874  THR n 
2 875  SER n 
2 876  ALA n 
2 877  LEU n 
2 878  LEU n 
2 879  ALA n 
2 880  GLY n 
2 881  THR n 
2 882  ILE n 
2 883  THR n 
2 884  SER n 
2 885  GLY n 
2 886  TRP n 
2 887  THR n 
2 888  PHE n 
2 889  GLY n 
2 890  ALA n 
2 891  GLY n 
2 892  ALA n 
2 893  ALA n 
2 894  LEU n 
2 895  GLN n 
2 896  ILE n 
2 897  PRO n 
2 898  PHE n 
2 899  ALA n 
2 900  MET n 
2 901  GLN n 
2 902  MET n 
2 903  ALA n 
2 904  TYR n 
2 905  ARG n 
2 906  PHE n 
2 907  ASN n 
2 908  GLY n 
2 909  ILE n 
2 910  GLY n 
2 911  VAL n 
2 912  THR n 
2 913  GLN n 
2 914  ASN n 
2 915  VAL n 
2 916  LEU n 
2 917  TYR n 
2 918  GLU n 
2 919  ASN n 
2 920  GLN n 
2 921  LYS n 
2 922  LEU n 
2 923  ILE n 
2 924  ALA n 
2 925  ASN n 
2 926  GLN n 
2 927  PHE n 
2 928  ASN n 
2 929  SER n 
2 930  ALA n 
2 931  ILE n 
2 932  GLY n 
2 933  LYS n 
2 934  ILE n 
2 935  GLN n 
2 936  ASP n 
2 937  SER n 
2 938  LEU n 
2 939  SER n 
2 940  SER n 
2 941  THR n 
2 942  ALA n 
2 943  SER n 
2 944  ALA n 
2 945  LEU n 
2 946  GLY n 
2 947  LYS n 
2 948  LEU n 
2 949  GLN n 
2 950  ASP n 
2 951  VAL n 
2 952  VAL n 
2 953  ASN n 
2 954  GLN n 
2 955  ASN n 
2 956  ALA n 
2 957  GLN n 
2 958  ALA n 
2 959  LEU n 
2 960  ASN n 
2 961  THR n 
2 962  LEU n 
2 963  VAL n 
2 964  LYS n 
2 965  GLN n 
2 966  LEU n 
2 967  SER n 
2 968  SER n 
2 969  ASN n 
2 970  PHE n 
2 971  GLY n 
2 972  ALA n 
2 973  ILE n 
2 974  SER n 
2 975  SER n 
2 976  VAL n 
2 977  LEU n 
2 978  ASN n 
2 979  ASP n 
2 980  ILE n 
2 981  LEU n 
2 982  SER n 
2 983  ARG n 
2 984  LEU n 
2 985  ASP n 
2 986  LYS n 
2 987  VAL n 
2 988  GLU n 
2 989  ALA n 
2 990  GLU n 
2 991  VAL n 
2 992  GLN n 
2 993  ILE n 
2 994  ASP n 
2 995  ARG n 
2 996  LEU n 
2 997  ILE n 
2 998  THR n 
2 999  GLY n 
2 1000 ARG n 
2 1001 LEU n 
2 1002 GLN n 
2 1003 SER n 
2 1004 LEU n 
2 1005 GLN n 
2 1006 THR n 
2 1007 TYR n 
2 1008 VAL n 
2 1009 THR n 
2 1010 GLN n 
2 1011 GLN n 
2 1012 LEU n 
2 1013 ILE n 
2 1014 ARG n 
2 1015 ALA n 
2 1016 ALA n 
2 1017 GLU n 
2 1018 ILE n 
2 1019 ARG n 
2 1020 ALA n 
2 1021 SER n 
2 1022 ALA n 
2 1023 ASN n 
2 1024 LEU n 
2 1025 ALA n 
2 1026 ALA n 
2 1027 THR n 
2 1028 LYS n 
2 1029 MET n 
2 1030 SER n 
2 1031 GLU n 
2 1032 CYS n 
2 1033 VAL n 
2 1034 LEU n 
2 1035 GLY n 
2 1036 GLN n 
2 1037 SER n 
2 1038 LYS n 
2 1039 ARG n 
2 1040 VAL n 
2 1041 ASP n 
2 1042 PHE n 
2 1043 CYS n 
2 1044 GLY n 
2 1045 LYS n 
2 1046 GLY n 
2 1047 TYR n 
2 1048 HIS n 
2 1049 LEU n 
2 1050 MET n 
2 1051 SER n 
2 1052 PHE n 
2 1053 PRO n 
2 1054 GLN n 
2 1055 SER n 
2 1056 ALA n 
2 1057 PRO n 
2 1058 HIS n 
2 1059 GLY n 
2 1060 VAL n 
2 1061 VAL n 
2 1062 PHE n 
2 1063 LEU n 
2 1064 HIS n 
2 1065 VAL n 
2 1066 THR n 
2 1067 TYR n 
2 1068 VAL n 
2 1069 PRO n 
2 1070 ALA n 
2 1071 GLN n 
2 1072 GLU n 
2 1073 LYS n 
2 1074 ASN n 
2 1075 PHE n 
2 1076 THR n 
2 1077 THR n 
2 1078 ALA n 
2 1079 PRO n 
2 1080 ALA n 
2 1081 ILE n 
2 1082 CYS n 
2 1083 HIS n 
2 1084 ASP n 
2 1085 GLY n 
2 1086 LYS n 
2 1087 ALA n 
2 1088 HIS n 
2 1089 PHE n 
2 1090 PRO n 
2 1091 ARG n 
2 1092 GLU n 
2 1093 GLY n 
2 1094 VAL n 
2 1095 PHE n 
2 1096 VAL n 
2 1097 SER n 
2 1098 ASN n 
2 1099 GLY n 
2 1100 THR n 
2 1101 HIS n 
2 1102 TRP n 
2 1103 PHE n 
2 1104 VAL n 
2 1105 THR n 
2 1106 GLN n 
2 1107 ARG n 
2 1108 ASN n 
2 1109 PHE n 
2 1110 TYR n 
2 1111 GLU n 
2 1112 PRO n 
2 1113 GLN n 
2 1114 ILE n 
2 1115 ILE n 
2 1116 THR n 
2 1117 THR n 
2 1118 ASP n 
2 1119 ASN n 
2 1120 THR n 
2 1121 PHE n 
2 1122 VAL n 
2 1123 SER n 
2 1124 GLY n 
2 1125 ASN n 
2 1126 CYS n 
2 1127 ASP n 
2 1128 VAL n 
2 1129 VAL n 
2 1130 ILE n 
2 1131 GLY n 
2 1132 ILE n 
2 1133 VAL n 
2 1134 ASN n 
2 1135 ASN n 
2 1136 THR n 
2 1137 VAL n 
2 1138 TYR n 
2 1139 ASP n 
2 1140 PRO n 
2 1141 LEU n 
2 1142 GLN n 
2 1143 PRO n 
2 1144 GLU n 
2 1145 LEU n 
2 1146 ASP n 
2 1147 SER n 
2 1148 PHE n 
2 1149 LYS n 
2 1150 GLU n 
2 1151 GLU n 
2 1152 LEU n 
2 1153 ASP n 
2 1154 LYS n 
2 1155 TYR n 
2 1156 PHE n 
2 1157 LYS n 
2 1158 ASN n 
2 1159 HIS n 
2 1160 THR n 
2 1161 SER n 
2 1162 PRO n 
2 1163 ASP n 
2 1164 VAL n 
2 1165 ASP n 
2 1166 LEU n 
2 1167 GLY n 
2 1168 ASP n 
2 1169 ILE n 
2 1170 SER n 
2 1171 GLY n 
2 1172 ILE n 
2 1173 ASN n 
2 1174 ALA n 
2 1175 SER n 
2 1176 VAL n 
2 1177 VAL n 
2 1178 ASN n 
2 1179 ILE n 
2 1180 GLN n 
2 1181 LYS n 
2 1182 GLU n 
2 1183 ILE n 
2 1184 ASP n 
2 1185 ARG n 
2 1186 LEU n 
2 1187 ASN n 
2 1188 GLU n 
2 1189 VAL n 
2 1190 ALA n 
2 1191 LYS n 
2 1192 ASN n 
2 1193 LEU n 
2 1194 ASN n 
2 1195 GLU n 
2 1196 SER n 
2 1197 LEU n 
2 1198 ILE n 
2 1199 ASP n 
2 1200 LEU n 
2 1201 GLN n 
2 1202 GLU n 
2 1203 LEU n 
2 1204 GLY n 
2 1205 LYS n 
2 1206 TYR n 
2 1207 GLU n 
2 1208 GLN n 
2 1209 GLY n 
2 1210 SER n 
2 1211 GLY n 
2 1212 TYR n 
2 1213 ILE n 
2 1214 PRO n 
2 1215 GLU n 
2 1216 ALA n 
2 1217 PRO n 
2 1218 ARG n 
2 1219 ASP n 
2 1220 GLY n 
2 1221 GLN n 
2 1222 ALA n 
2 1223 TYR n 
2 1224 VAL n 
2 1225 ARG n 
2 1226 LYS n 
2 1227 ASP n 
2 1228 GLY n 
2 1229 GLU n 
2 1230 TRP n 
2 1231 VAL n 
2 1232 PHE n 
2 1233 LEU n 
2 1234 SER n 
2 1235 THR n 
2 1236 PHE n 
2 1237 LEU n 
2 1238 SER n 
2 1239 GLY n 
2 1240 LEU n 
2 1241 GLU n 
2 1242 VAL n 
2 1243 LEU n 
2 1244 PHE n 
2 1245 GLN n 
2 1246 GLY n 
2 1247 PRO n 
2 1248 GLY n 
2 1249 GLY n 
2 1250 TRP n 
2 1251 SER n 
2 1252 HIS n 
2 1253 PRO n 
2 1254 GLN n 
2 1255 PHE n 
2 1256 GLU n 
2 1257 LYS n 
2 1258 GLY n 
2 1259 GLY n 
2 1260 GLY n 
2 1261 SER n 
2 1262 GLY n 
2 1263 GLY n 
2 1264 GLY n 
2 1265 SER n 
2 1266 GLY n 
2 1267 GLY n 
2 1268 SER n 
2 1269 ALA n 
2 1270 TRP n 
2 1271 SER n 
2 1272 HIS n 
2 1273 PRO n 
2 1274 GLN n 
2 1275 PHE n 
2 1276 GLU n 
2 1277 LYS n 
2 1278 GLY n 
2 1279 GLY n 
2 1280 SER n 
2 1281 HIS n 
2 1282 HIS n 
2 1283 HIS n 
2 1284 HIS n 
2 1285 HIS n 
2 1286 HIS n 
2 1287 HIS n 
2 1288 HIS n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 631  human ? 'ACE2, UNQ868/PRO1885' ? ? ? ? ? ? 'Homo sapiens' 9606    ? ? ? ? ? ? ? ? 
'Homo sapiens' 9606 ? ? ? ? ? ? ? ? HEK293F ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 1288 ?     ? 'S, 2'                 ? ? ? ? ? ? 
'Severe acute respiratory syndrome coronavirus 2' 2697049 ? ? ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? HEK293F ? ? ? ? ? ? 
? ? ? ? ? ? 
# 
loop_
_pdbx_entity_branch.entity_id 
_pdbx_entity_branch.type 
3 oligosaccharide 
4 oligosaccharide 
# 
loop_
_pdbx_entity_branch_descriptor.ordinal 
_pdbx_entity_branch_descriptor.entity_id 
_pdbx_entity_branch_descriptor.descriptor 
_pdbx_entity_branch_descriptor.type 
_pdbx_entity_branch_descriptor.program 
_pdbx_entity_branch_descriptor.program_version 
1 3 DGlcpNAcb1-4DGlcpNAcb1-                                                      'Glycam Condensed Sequence' GMML       1.0   
2 3 'WURCS=2.0/1,2,1/[a2122h-1b_1-5_2*NCC/3=O]/1-1/a4-b1'                        WURCS                       PDB2Glycan 1.1.0 
3 3 '[]{[(4+1)][b-D-GlcpNAc]{[(4+1)][b-D-GlcpNAc]{}}}'                           LINUCS                      PDB-CARE   ?     
4 4 DManpb1-4DGlcpNAcb1-4DGlcpNAcb1-                                             'Glycam Condensed Sequence' GMML       1.0   
5 4 'WURCS=2.0/2,3,2/[a2122h-1b_1-5_2*NCC/3=O][a1122h-1b_1-5]/1-1-2/a4-b1_b4-c1' WURCS                       PDB2Glycan 1.1.0 
6 4 '[]{[(4+1)][b-D-GlcpNAc]{[(4+1)][b-D-GlcpNAc]{[(4+1)][b-D-Manp]{}}}}'        LINUCS                      PDB-CARE   ?     
# 
loop_
_pdbx_entity_branch_link.link_id 
_pdbx_entity_branch_link.entity_id 
_pdbx_entity_branch_link.entity_branch_list_num_1 
_pdbx_entity_branch_link.comp_id_1 
_pdbx_entity_branch_link.atom_id_1 
_pdbx_entity_branch_link.leaving_atom_id_1 
_pdbx_entity_branch_link.entity_branch_list_num_2 
_pdbx_entity_branch_link.comp_id_2 
_pdbx_entity_branch_link.atom_id_2 
_pdbx_entity_branch_link.leaving_atom_id_2 
_pdbx_entity_branch_link.value_order 
_pdbx_entity_branch_link.details 
1 3 2 NAG C1 O1 1 NAG O4 HO4 sing ? 
2 4 2 NAG C1 O1 1 NAG O4 HO4 sing ? 
3 4 3 BMA C1 O1 2 NAG O4 HO4 sing ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking'          y ALANINE                                  ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking'          y ARGININE                                 ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking'          y ASPARAGINE                               ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking'          y 'ASPARTIC ACID'                          ? 'C4 H7 N O4'     133.103 
BMA 'D-saccharide, beta linking' . beta-D-mannopyranose                     'beta-D-mannose; D-mannose; mannose' 'C6 H12 O6'      
180.156 
CYS 'L-peptide linking'          y CYSTEINE                                 ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking'          y GLUTAMINE                                ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking'          y 'GLUTAMIC ACID'                          ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'            y GLYCINE                                  ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking'          y HISTIDINE                                ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking'          y ISOLEUCINE                               ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking'          y LEUCINE                                  ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking'          y LYSINE                                   ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking'          y METHIONINE                               ? 'C5 H11 N O2 S'  149.211 
NAG 'D-saccharide, beta linking' . 2-acetamido-2-deoxy-beta-D-glucopyranose 
;N-acetyl-beta-D-glucosamine; 2-acetamido-2-deoxy-beta-D-glucose; 2-acetamido-2-deoxy-D-glucose; 2-acetamido-2-deoxy-glucose; N-ACETYL-D-GLUCOSAMINE
;
'C8 H15 N O6'    221.208 
PHE 'L-peptide linking'          y PHENYLALANINE                            ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking'          y PROLINE                                  ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking'          y SERINE                                   ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking'          y THREONINE                                ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking'          y TRYPTOPHAN                               ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking'          y TYROSINE                                 ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking'          y VALINE                                   ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_chem_comp_identifier.comp_id 
_pdbx_chem_comp_identifier.type 
_pdbx_chem_comp_identifier.program 
_pdbx_chem_comp_identifier.program_version 
_pdbx_chem_comp_identifier.identifier 
BMA 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DManpb                         
BMA 'COMMON NAME'                         GMML     1.0 b-D-mannopyranose              
BMA 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 b-D-Manp                       
BMA 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 Man                            
NAG 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DGlcpNAcb                      
NAG 'COMMON NAME'                         GMML     1.0 N-acetyl-b-D-glucopyranosamine 
NAG 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 b-D-GlcpNAc                    
NAG 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 GlcNAc                         
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1    MET 1    1    ?   ?   ?   D . n 
A 1 2    SER 2    2    ?   ?   ?   D . n 
A 1 3    SER 3    3    ?   ?   ?   D . n 
A 1 4    SER 4    4    ?   ?   ?   D . n 
A 1 5    SER 5    5    ?   ?   ?   D . n 
A 1 6    TRP 6    6    ?   ?   ?   D . n 
A 1 7    LEU 7    7    ?   ?   ?   D . n 
A 1 8    LEU 8    8    ?   ?   ?   D . n 
A 1 9    LEU 9    9    ?   ?   ?   D . n 
A 1 10   SER 10   10   ?   ?   ?   D . n 
A 1 11   LEU 11   11   ?   ?   ?   D . n 
A 1 12   VAL 12   12   ?   ?   ?   D . n 
A 1 13   ALA 13   13   ?   ?   ?   D . n 
A 1 14   VAL 14   14   ?   ?   ?   D . n 
A 1 15   THR 15   15   ?   ?   ?   D . n 
A 1 16   ALA 16   16   ?   ?   ?   D . n 
A 1 17   ALA 17   17   ?   ?   ?   D . n 
A 1 18   GLN 18   18   ?   ?   ?   D . n 
A 1 19   SER 19   19   19  SER SER D . n 
A 1 20   THR 20   20   20  THR THR D . n 
A 1 21   ILE 21   21   21  ILE ILE D . n 
A 1 22   GLU 22   22   22  GLU GLU D . n 
A 1 23   GLU 23   23   23  GLU GLU D . n 
A 1 24   GLN 24   24   24  GLN GLN D . n 
A 1 25   ALA 25   25   25  ALA ALA D . n 
A 1 26   LYS 26   26   26  LYS LYS D . n 
A 1 27   THR 27   27   27  THR THR D . n 
A 1 28   PHE 28   28   28  PHE PHE D . n 
A 1 29   LEU 29   29   29  LEU LEU D . n 
A 1 30   ASP 30   30   30  ASP ASP D . n 
A 1 31   LYS 31   31   31  LYS LYS D . n 
A 1 32   PHE 32   32   32  PHE PHE D . n 
A 1 33   ASN 33   33   33  ASN ASN D . n 
A 1 34   HIS 34   34   34  HIS HIS D . n 
A 1 35   GLU 35   35   35  GLU GLU D . n 
A 1 36   ALA 36   36   36  ALA ALA D . n 
A 1 37   GLU 37   37   37  GLU GLU D . n 
A 1 38   ASP 38   38   38  ASP ASP D . n 
A 1 39   LEU 39   39   39  LEU LEU D . n 
A 1 40   PHE 40   40   40  PHE PHE D . n 
A 1 41   TYR 41   41   41  TYR TYR D . n 
A 1 42   GLN 42   42   42  GLN GLN D . n 
A 1 43   SER 43   43   43  SER SER D . n 
A 1 44   SER 44   44   44  SER SER D . n 
A 1 45   LEU 45   45   45  LEU LEU D . n 
A 1 46   ALA 46   46   46  ALA ALA D . n 
A 1 47   SER 47   47   47  SER SER D . n 
A 1 48   TRP 48   48   48  TRP TRP D . n 
A 1 49   ASN 49   49   49  ASN ASN D . n 
A 1 50   TYR 50   50   50  TYR TYR D . n 
A 1 51   ASN 51   51   51  ASN ASN D . n 
A 1 52   THR 52   52   52  THR THR D . n 
A 1 53   ASN 53   53   53  ASN ASN D . n 
A 1 54   ILE 54   54   54  ILE ILE D . n 
A 1 55   THR 55   55   55  THR THR D . n 
A 1 56   GLU 56   56   56  GLU GLU D . n 
A 1 57   GLU 57   57   57  GLU GLU D . n 
A 1 58   ASN 58   58   58  ASN ASN D . n 
A 1 59   VAL 59   59   59  VAL VAL D . n 
A 1 60   GLN 60   60   60  GLN GLN D . n 
A 1 61   ASN 61   61   61  ASN ASN D . n 
A 1 62   MET 62   62   62  MET MET D . n 
A 1 63   ASN 63   63   63  ASN ASN D . n 
A 1 64   ASN 64   64   64  ASN ASN D . n 
A 1 65   ALA 65   65   65  ALA ALA D . n 
A 1 66   GLY 66   66   66  GLY GLY D . n 
A 1 67   ASP 67   67   67  ASP ASP D . n 
A 1 68   LYS 68   68   68  LYS LYS D . n 
A 1 69   TRP 69   69   69  TRP TRP D . n 
A 1 70   SER 70   70   70  SER SER D . n 
A 1 71   ALA 71   71   71  ALA ALA D . n 
A 1 72   PHE 72   72   72  PHE PHE D . n 
A 1 73   LEU 73   73   73  LEU LEU D . n 
A 1 74   LYS 74   74   74  LYS LYS D . n 
A 1 75   GLU 75   75   75  GLU GLU D . n 
A 1 76   GLN 76   76   76  GLN GLN D . n 
A 1 77   SER 77   77   77  SER SER D . n 
A 1 78   THR 78   78   78  THR THR D . n 
A 1 79   LEU 79   79   79  LEU LEU D . n 
A 1 80   ALA 80   80   80  ALA ALA D . n 
A 1 81   GLN 81   81   81  GLN GLN D . n 
A 1 82   MET 82   82   82  MET MET D . n 
A 1 83   TYR 83   83   83  TYR TYR D . n 
A 1 84   PRO 84   84   84  PRO PRO D . n 
A 1 85   LEU 85   85   85  LEU LEU D . n 
A 1 86   GLN 86   86   86  GLN GLN D . n 
A 1 87   GLU 87   87   87  GLU GLU D . n 
A 1 88   ILE 88   88   88  ILE ILE D . n 
A 1 89   GLN 89   89   89  GLN GLN D . n 
A 1 90   ASN 90   90   90  ASN ASN D . n 
A 1 91   LEU 91   91   91  LEU LEU D . n 
A 1 92   THR 92   92   92  THR THR D . n 
A 1 93   VAL 93   93   93  VAL VAL D . n 
A 1 94   LYS 94   94   94  LYS LYS D . n 
A 1 95   LEU 95   95   95  LEU LEU D . n 
A 1 96   GLN 96   96   96  GLN GLN D . n 
A 1 97   LEU 97   97   97  LEU LEU D . n 
A 1 98   GLN 98   98   98  GLN GLN D . n 
A 1 99   ALA 99   99   99  ALA ALA D . n 
A 1 100  LEU 100  100  100 LEU LEU D . n 
A 1 101  GLN 101  101  101 GLN GLN D . n 
A 1 102  GLN 102  102  102 GLN GLN D . n 
A 1 103  ASN 103  103  103 ASN ASN D . n 
A 1 104  GLY 104  104  104 GLY GLY D . n 
A 1 105  SER 105  105  105 SER SER D . n 
A 1 106  SER 106  106  106 SER SER D . n 
A 1 107  VAL 107  107  107 VAL VAL D . n 
A 1 108  LEU 108  108  108 LEU LEU D . n 
A 1 109  SER 109  109  109 SER SER D . n 
A 1 110  GLU 110  110  110 GLU GLU D . n 
A 1 111  ASP 111  111  111 ASP ASP D . n 
A 1 112  LYS 112  112  112 LYS LYS D . n 
A 1 113  SER 113  113  113 SER SER D . n 
A 1 114  LYS 114  114  114 LYS LYS D . n 
A 1 115  ARG 115  115  115 ARG ARG D . n 
A 1 116  LEU 116  116  116 LEU LEU D . n 
A 1 117  ASN 117  117  117 ASN ASN D . n 
A 1 118  THR 118  118  118 THR THR D . n 
A 1 119  ILE 119  119  119 ILE ILE D . n 
A 1 120  LEU 120  120  120 LEU LEU D . n 
A 1 121  ASN 121  121  121 ASN ASN D . n 
A 1 122  THR 122  122  122 THR THR D . n 
A 1 123  MET 123  123  123 MET MET D . n 
A 1 124  SER 124  124  124 SER SER D . n 
A 1 125  THR 125  125  125 THR THR D . n 
A 1 126  ILE 126  126  126 ILE ILE D . n 
A 1 127  TYR 127  127  127 TYR TYR D . n 
A 1 128  SER 128  128  128 SER SER D . n 
A 1 129  THR 129  129  129 THR THR D . n 
A 1 130  GLY 130  130  130 GLY GLY D . n 
A 1 131  LYS 131  131  131 LYS LYS D . n 
A 1 132  VAL 132  132  132 VAL VAL D . n 
A 1 133  CYS 133  133  133 CYS CYS D . n 
A 1 134  ASN 134  134  134 ASN ASN D . n 
A 1 135  PRO 135  135  135 PRO PRO D . n 
A 1 136  ASP 136  136  136 ASP ASP D . n 
A 1 137  ASN 137  137  137 ASN ASN D . n 
A 1 138  PRO 138  138  138 PRO PRO D . n 
A 1 139  GLN 139  139  139 GLN GLN D . n 
A 1 140  GLU 140  140  140 GLU GLU D . n 
A 1 141  CYS 141  141  141 CYS CYS D . n 
A 1 142  LEU 142  142  142 LEU LEU D . n 
A 1 143  LEU 143  143  143 LEU LEU D . n 
A 1 144  LEU 144  144  144 LEU LEU D . n 
A 1 145  GLU 145  145  145 GLU GLU D . n 
A 1 146  PRO 146  146  146 PRO PRO D . n 
A 1 147  GLY 147  147  147 GLY GLY D . n 
A 1 148  LEU 148  148  148 LEU LEU D . n 
A 1 149  ASN 149  149  149 ASN ASN D . n 
A 1 150  GLU 150  150  150 GLU GLU D . n 
A 1 151  ILE 151  151  151 ILE ILE D . n 
A 1 152  MET 152  152  152 MET MET D . n 
A 1 153  ALA 153  153  153 ALA ALA D . n 
A 1 154  ASN 154  154  154 ASN ASN D . n 
A 1 155  SER 155  155  155 SER SER D . n 
A 1 156  LEU 156  156  156 LEU LEU D . n 
A 1 157  ASP 157  157  157 ASP ASP D . n 
A 1 158  TYR 158  158  158 TYR TYR D . n 
A 1 159  ASN 159  159  159 ASN ASN D . n 
A 1 160  GLU 160  160  160 GLU GLU D . n 
A 1 161  ARG 161  161  161 ARG ARG D . n 
A 1 162  LEU 162  162  162 LEU LEU D . n 
A 1 163  TRP 163  163  163 TRP TRP D . n 
A 1 164  ALA 164  164  164 ALA ALA D . n 
A 1 165  TRP 165  165  165 TRP TRP D . n 
A 1 166  GLU 166  166  166 GLU GLU D . n 
A 1 167  SER 167  167  167 SER SER D . n 
A 1 168  TRP 168  168  168 TRP TRP D . n 
A 1 169  ARG 169  169  169 ARG ARG D . n 
A 1 170  SER 170  170  170 SER SER D . n 
A 1 171  GLU 171  171  171 GLU GLU D . n 
A 1 172  VAL 172  172  172 VAL VAL D . n 
A 1 173  GLY 173  173  173 GLY GLY D . n 
A 1 174  LYS 174  174  174 LYS LYS D . n 
A 1 175  GLN 175  175  175 GLN GLN D . n 
A 1 176  LEU 176  176  176 LEU LEU D . n 
A 1 177  ARG 177  177  177 ARG ARG D . n 
A 1 178  PRO 178  178  178 PRO PRO D . n 
A 1 179  LEU 179  179  179 LEU LEU D . n 
A 1 180  TYR 180  180  180 TYR TYR D . n 
A 1 181  GLU 181  181  181 GLU GLU D . n 
A 1 182  GLU 182  182  182 GLU GLU D . n 
A 1 183  TYR 183  183  183 TYR TYR D . n 
A 1 184  VAL 184  184  184 VAL VAL D . n 
A 1 185  VAL 185  185  185 VAL VAL D . n 
A 1 186  LEU 186  186  186 LEU LEU D . n 
A 1 187  LYS 187  187  187 LYS LYS D . n 
A 1 188  ASN 188  188  188 ASN ASN D . n 
A 1 189  GLU 189  189  189 GLU GLU D . n 
A 1 190  MET 190  190  190 MET MET D . n 
A 1 191  ALA 191  191  191 ALA ALA D . n 
A 1 192  ARG 192  192  192 ARG ARG D . n 
A 1 193  ALA 193  193  193 ALA ALA D . n 
A 1 194  ASN 194  194  194 ASN ASN D . n 
A 1 195  HIS 195  195  195 HIS HIS D . n 
A 1 196  TYR 196  196  196 TYR TYR D . n 
A 1 197  GLU 197  197  197 GLU GLU D . n 
A 1 198  ASP 198  198  198 ASP ASP D . n 
A 1 199  TYR 199  199  199 TYR TYR D . n 
A 1 200  GLY 200  200  200 GLY GLY D . n 
A 1 201  ASP 201  201  201 ASP ASP D . n 
A 1 202  TYR 202  202  202 TYR TYR D . n 
A 1 203  TRP 203  203  203 TRP TRP D . n 
A 1 204  ARG 204  204  204 ARG ARG D . n 
A 1 205  GLY 205  205  205 GLY GLY D . n 
A 1 206  ASP 206  206  206 ASP ASP D . n 
A 1 207  TYR 207  207  207 TYR TYR D . n 
A 1 208  GLU 208  208  208 GLU GLU D . n 
A 1 209  VAL 209  209  209 VAL VAL D . n 
A 1 210  ASN 210  210  210 ASN ASN D . n 
A 1 211  GLY 211  211  211 GLY GLY D . n 
A 1 212  VAL 212  212  212 VAL VAL D . n 
A 1 213  ASP 213  213  213 ASP ASP D . n 
A 1 214  GLY 214  214  214 GLY GLY D . n 
A 1 215  TYR 215  215  215 TYR TYR D . n 
A 1 216  ASP 216  216  216 ASP ASP D . n 
A 1 217  TYR 217  217  217 TYR TYR D . n 
A 1 218  SER 218  218  218 SER SER D . n 
A 1 219  ARG 219  219  219 ARG ARG D . n 
A 1 220  GLY 220  220  220 GLY GLY D . n 
A 1 221  GLN 221  221  221 GLN GLN D . n 
A 1 222  LEU 222  222  222 LEU LEU D . n 
A 1 223  ILE 223  223  223 ILE ILE D . n 
A 1 224  GLU 224  224  224 GLU GLU D . n 
A 1 225  ASP 225  225  225 ASP ASP D . n 
A 1 226  VAL 226  226  226 VAL VAL D . n 
A 1 227  GLU 227  227  227 GLU GLU D . n 
A 1 228  HIS 228  228  228 HIS HIS D . n 
A 1 229  THR 229  229  229 THR THR D . n 
A 1 230  PHE 230  230  230 PHE PHE D . n 
A 1 231  GLU 231  231  231 GLU GLU D . n 
A 1 232  GLU 232  232  232 GLU GLU D . n 
A 1 233  ILE 233  233  233 ILE ILE D . n 
A 1 234  LYS 234  234  234 LYS LYS D . n 
A 1 235  PRO 235  235  235 PRO PRO D . n 
A 1 236  LEU 236  236  236 LEU LEU D . n 
A 1 237  TYR 237  237  237 TYR TYR D . n 
A 1 238  GLU 238  238  238 GLU GLU D . n 
A 1 239  HIS 239  239  239 HIS HIS D . n 
A 1 240  LEU 240  240  240 LEU LEU D . n 
A 1 241  HIS 241  241  241 HIS HIS D . n 
A 1 242  ALA 242  242  242 ALA ALA D . n 
A 1 243  TYR 243  243  243 TYR TYR D . n 
A 1 244  VAL 244  244  244 VAL VAL D . n 
A 1 245  ARG 245  245  245 ARG ARG D . n 
A 1 246  ALA 246  246  246 ALA ALA D . n 
A 1 247  LYS 247  247  247 LYS LYS D . n 
A 1 248  LEU 248  248  248 LEU LEU D . n 
A 1 249  MET 249  249  249 MET MET D . n 
A 1 250  ASN 250  250  250 ASN ASN D . n 
A 1 251  ALA 251  251  251 ALA ALA D . n 
A 1 252  TYR 252  252  252 TYR TYR D . n 
A 1 253  PRO 253  253  253 PRO PRO D . n 
A 1 254  SER 254  254  254 SER SER D . n 
A 1 255  TYR 255  255  255 TYR TYR D . n 
A 1 256  ILE 256  256  256 ILE ILE D . n 
A 1 257  SER 257  257  257 SER SER D . n 
A 1 258  PRO 258  258  258 PRO PRO D . n 
A 1 259  ILE 259  259  259 ILE ILE D . n 
A 1 260  GLY 260  260  260 GLY GLY D . n 
A 1 261  CYS 261  261  261 CYS CYS D . n 
A 1 262  LEU 262  262  262 LEU LEU D . n 
A 1 263  PRO 263  263  263 PRO PRO D . n 
A 1 264  ALA 264  264  264 ALA ALA D . n 
A 1 265  HIS 265  265  265 HIS HIS D . n 
A 1 266  LEU 266  266  266 LEU LEU D . n 
A 1 267  LEU 267  267  267 LEU LEU D . n 
A 1 268  GLY 268  268  268 GLY GLY D . n 
A 1 269  ASP 269  269  269 ASP ASP D . n 
A 1 270  MET 270  270  270 MET MET D . n 
A 1 271  TRP 271  271  271 TRP TRP D . n 
A 1 272  GLY 272  272  272 GLY GLY D . n 
A 1 273  ARG 273  273  273 ARG ARG D . n 
A 1 274  PHE 274  274  274 PHE PHE D . n 
A 1 275  TRP 275  275  275 TRP TRP D . n 
A 1 276  THR 276  276  276 THR THR D . n 
A 1 277  ASN 277  277  277 ASN ASN D . n 
A 1 278  LEU 278  278  278 LEU LEU D . n 
A 1 279  TYR 279  279  279 TYR TYR D . n 
A 1 280  SER 280  280  280 SER SER D . n 
A 1 281  LEU 281  281  281 LEU LEU D . n 
A 1 282  THR 282  282  282 THR THR D . n 
A 1 283  VAL 283  283  283 VAL VAL D . n 
A 1 284  PRO 284  284  284 PRO PRO D . n 
A 1 285  PHE 285  285  285 PHE PHE D . n 
A 1 286  GLY 286  286  286 GLY GLY D . n 
A 1 287  GLN 287  287  287 GLN GLN D . n 
A 1 288  LYS 288  288  288 LYS LYS D . n 
A 1 289  PRO 289  289  289 PRO PRO D . n 
A 1 290  ASN 290  290  290 ASN ASN D . n 
A 1 291  ILE 291  291  291 ILE ILE D . n 
A 1 292  ASP 292  292  292 ASP ASP D . n 
A 1 293  VAL 293  293  293 VAL VAL D . n 
A 1 294  THR 294  294  294 THR THR D . n 
A 1 295  ASP 295  295  295 ASP ASP D . n 
A 1 296  ALA 296  296  296 ALA ALA D . n 
A 1 297  MET 297  297  297 MET MET D . n 
A 1 298  VAL 298  298  298 VAL VAL D . n 
A 1 299  ASP 299  299  299 ASP ASP D . n 
A 1 300  GLN 300  300  300 GLN GLN D . n 
A 1 301  ALA 301  301  301 ALA ALA D . n 
A 1 302  TRP 302  302  302 TRP TRP D . n 
A 1 303  ASP 303  303  303 ASP ASP D . n 
A 1 304  ALA 304  304  304 ALA ALA D . n 
A 1 305  GLN 305  305  305 GLN GLN D . n 
A 1 306  ARG 306  306  306 ARG ARG D . n 
A 1 307  ILE 307  307  307 ILE ILE D . n 
A 1 308  PHE 308  308  308 PHE PHE D . n 
A 1 309  LYS 309  309  309 LYS LYS D . n 
A 1 310  GLU 310  310  310 GLU GLU D . n 
A 1 311  ALA 311  311  311 ALA ALA D . n 
A 1 312  GLU 312  312  312 GLU GLU D . n 
A 1 313  LYS 313  313  313 LYS LYS D . n 
A 1 314  PHE 314  314  314 PHE PHE D . n 
A 1 315  PHE 315  315  315 PHE PHE D . n 
A 1 316  VAL 316  316  316 VAL VAL D . n 
A 1 317  SER 317  317  317 SER SER D . n 
A 1 318  VAL 318  318  318 VAL VAL D . n 
A 1 319  GLY 319  319  319 GLY GLY D . n 
A 1 320  LEU 320  320  320 LEU LEU D . n 
A 1 321  PRO 321  321  321 PRO PRO D . n 
A 1 322  ASN 322  322  322 ASN ASN D . n 
A 1 323  MET 323  323  323 MET MET D . n 
A 1 324  THR 324  324  324 THR THR D . n 
A 1 325  GLN 325  325  325 GLN GLN D . n 
A 1 326  GLY 326  326  326 GLY GLY D . n 
A 1 327  PHE 327  327  327 PHE PHE D . n 
A 1 328  TRP 328  328  328 TRP TRP D . n 
A 1 329  GLU 329  329  329 GLU GLU D . n 
A 1 330  ASN 330  330  330 ASN ASN D . n 
A 1 331  SER 331  331  331 SER SER D . n 
A 1 332  MET 332  332  332 MET MET D . n 
A 1 333  LEU 333  333  333 LEU LEU D . n 
A 1 334  THR 334  334  334 THR THR D . n 
A 1 335  ASP 335  335  335 ASP ASP D . n 
A 1 336  PRO 336  336  336 PRO PRO D . n 
A 1 337  GLY 337  337  337 GLY GLY D . n 
A 1 338  ASN 338  338  338 ASN ASN D . n 
A 1 339  VAL 339  339  339 VAL VAL D . n 
A 1 340  GLN 340  340  340 GLN GLN D . n 
A 1 341  LYS 341  341  341 LYS LYS D . n 
A 1 342  ALA 342  342  342 ALA ALA D . n 
A 1 343  VAL 343  343  343 VAL VAL D . n 
A 1 344  CYS 344  344  344 CYS CYS D . n 
A 1 345  HIS 345  345  345 HIS HIS D . n 
A 1 346  PRO 346  346  346 PRO PRO D . n 
A 1 347  THR 347  347  347 THR THR D . n 
A 1 348  ALA 348  348  348 ALA ALA D . n 
A 1 349  TRP 349  349  349 TRP TRP D . n 
A 1 350  ASP 350  350  350 ASP ASP D . n 
A 1 351  LEU 351  351  351 LEU LEU D . n 
A 1 352  GLY 352  352  352 GLY GLY D . n 
A 1 353  LYS 353  353  353 LYS LYS D . n 
A 1 354  GLY 354  354  354 GLY GLY D . n 
A 1 355  ASP 355  355  355 ASP ASP D . n 
A 1 356  PHE 356  356  356 PHE PHE D . n 
A 1 357  ARG 357  357  357 ARG ARG D . n 
A 1 358  ILE 358  358  358 ILE ILE D . n 
A 1 359  LEU 359  359  359 LEU LEU D . n 
A 1 360  MET 360  360  360 MET MET D . n 
A 1 361  CYS 361  361  361 CYS CYS D . n 
A 1 362  THR 362  362  362 THR THR D . n 
A 1 363  LYS 363  363  363 LYS LYS D . n 
A 1 364  VAL 364  364  364 VAL VAL D . n 
A 1 365  THR 365  365  365 THR THR D . n 
A 1 366  MET 366  366  366 MET MET D . n 
A 1 367  ASP 367  367  367 ASP ASP D . n 
A 1 368  ASP 368  368  368 ASP ASP D . n 
A 1 369  PHE 369  369  369 PHE PHE D . n 
A 1 370  LEU 370  370  370 LEU LEU D . n 
A 1 371  THR 371  371  371 THR THR D . n 
A 1 372  ALA 372  372  372 ALA ALA D . n 
A 1 373  HIS 373  373  373 HIS HIS D . n 
A 1 374  HIS 374  374  374 HIS HIS D . n 
A 1 375  GLU 375  375  375 GLU GLU D . n 
A 1 376  MET 376  376  376 MET MET D . n 
A 1 377  GLY 377  377  377 GLY GLY D . n 
A 1 378  HIS 378  378  378 HIS HIS D . n 
A 1 379  ILE 379  379  379 ILE ILE D . n 
A 1 380  GLN 380  380  380 GLN GLN D . n 
A 1 381  TYR 381  381  381 TYR TYR D . n 
A 1 382  ASP 382  382  382 ASP ASP D . n 
A 1 383  MET 383  383  383 MET MET D . n 
A 1 384  ALA 384  384  384 ALA ALA D . n 
A 1 385  TYR 385  385  385 TYR TYR D . n 
A 1 386  ALA 386  386  386 ALA ALA D . n 
A 1 387  ALA 387  387  387 ALA ALA D . n 
A 1 388  GLN 388  388  388 GLN GLN D . n 
A 1 389  PRO 389  389  389 PRO PRO D . n 
A 1 390  PHE 390  390  390 PHE PHE D . n 
A 1 391  LEU 391  391  391 LEU LEU D . n 
A 1 392  LEU 392  392  392 LEU LEU D . n 
A 1 393  ARG 393  393  393 ARG ARG D . n 
A 1 394  ASN 394  394  394 ASN ASN D . n 
A 1 395  GLY 395  395  395 GLY GLY D . n 
A 1 396  ALA 396  396  396 ALA ALA D . n 
A 1 397  ASN 397  397  397 ASN ASN D . n 
A 1 398  GLU 398  398  398 GLU GLU D . n 
A 1 399  GLY 399  399  399 GLY GLY D . n 
A 1 400  PHE 400  400  400 PHE PHE D . n 
A 1 401  HIS 401  401  401 HIS HIS D . n 
A 1 402  GLU 402  402  402 GLU GLU D . n 
A 1 403  ALA 403  403  403 ALA ALA D . n 
A 1 404  VAL 404  404  404 VAL VAL D . n 
A 1 405  GLY 405  405  405 GLY GLY D . n 
A 1 406  GLU 406  406  406 GLU GLU D . n 
A 1 407  ILE 407  407  407 ILE ILE D . n 
A 1 408  MET 408  408  408 MET MET D . n 
A 1 409  SER 409  409  409 SER SER D . n 
A 1 410  LEU 410  410  410 LEU LEU D . n 
A 1 411  SER 411  411  411 SER SER D . n 
A 1 412  ALA 412  412  412 ALA ALA D . n 
A 1 413  ALA 413  413  413 ALA ALA D . n 
A 1 414  THR 414  414  414 THR THR D . n 
A 1 415  PRO 415  415  415 PRO PRO D . n 
A 1 416  LYS 416  416  416 LYS LYS D . n 
A 1 417  HIS 417  417  417 HIS HIS D . n 
A 1 418  LEU 418  418  418 LEU LEU D . n 
A 1 419  LYS 419  419  419 LYS LYS D . n 
A 1 420  SER 420  420  420 SER SER D . n 
A 1 421  ILE 421  421  421 ILE ILE D . n 
A 1 422  GLY 422  422  422 GLY GLY D . n 
A 1 423  LEU 423  423  423 LEU LEU D . n 
A 1 424  LEU 424  424  424 LEU LEU D . n 
A 1 425  SER 425  425  425 SER SER D . n 
A 1 426  PRO 426  426  426 PRO PRO D . n 
A 1 427  ASP 427  427  427 ASP ASP D . n 
A 1 428  PHE 428  428  428 PHE PHE D . n 
A 1 429  GLN 429  429  429 GLN GLN D . n 
A 1 430  GLU 430  430  430 GLU GLU D . n 
A 1 431  ASP 431  431  431 ASP ASP D . n 
A 1 432  ASN 432  432  432 ASN ASN D . n 
A 1 433  GLU 433  433  433 GLU GLU D . n 
A 1 434  THR 434  434  434 THR THR D . n 
A 1 435  GLU 435  435  435 GLU GLU D . n 
A 1 436  ILE 436  436  436 ILE ILE D . n 
A 1 437  ASN 437  437  437 ASN ASN D . n 
A 1 438  PHE 438  438  438 PHE PHE D . n 
A 1 439  LEU 439  439  439 LEU LEU D . n 
A 1 440  LEU 440  440  440 LEU LEU D . n 
A 1 441  LYS 441  441  441 LYS LYS D . n 
A 1 442  GLN 442  442  442 GLN GLN D . n 
A 1 443  ALA 443  443  443 ALA ALA D . n 
A 1 444  LEU 444  444  444 LEU LEU D . n 
A 1 445  THR 445  445  445 THR THR D . n 
A 1 446  ILE 446  446  446 ILE ILE D . n 
A 1 447  VAL 447  447  447 VAL VAL D . n 
A 1 448  GLY 448  448  448 GLY GLY D . n 
A 1 449  THR 449  449  449 THR THR D . n 
A 1 450  LEU 450  450  450 LEU LEU D . n 
A 1 451  PRO 451  451  451 PRO PRO D . n 
A 1 452  PHE 452  452  452 PHE PHE D . n 
A 1 453  THR 453  453  453 THR THR D . n 
A 1 454  TYR 454  454  454 TYR TYR D . n 
A 1 455  MET 455  455  455 MET MET D . n 
A 1 456  LEU 456  456  456 LEU LEU D . n 
A 1 457  GLU 457  457  457 GLU GLU D . n 
A 1 458  LYS 458  458  458 LYS LYS D . n 
A 1 459  TRP 459  459  459 TRP TRP D . n 
A 1 460  ARG 460  460  460 ARG ARG D . n 
A 1 461  TRP 461  461  461 TRP TRP D . n 
A 1 462  MET 462  462  462 MET MET D . n 
A 1 463  VAL 463  463  463 VAL VAL D . n 
A 1 464  PHE 464  464  464 PHE PHE D . n 
A 1 465  LYS 465  465  465 LYS LYS D . n 
A 1 466  GLY 466  466  466 GLY GLY D . n 
A 1 467  GLU 467  467  467 GLU GLU D . n 
A 1 468  ILE 468  468  468 ILE ILE D . n 
A 1 469  PRO 469  469  469 PRO PRO D . n 
A 1 470  LYS 470  470  470 LYS LYS D . n 
A 1 471  ASP 471  471  471 ASP ASP D . n 
A 1 472  GLN 472  472  472 GLN GLN D . n 
A 1 473  TRP 473  473  473 TRP TRP D . n 
A 1 474  MET 474  474  474 MET MET D . n 
A 1 475  LYS 475  475  475 LYS LYS D . n 
A 1 476  LYS 476  476  476 LYS LYS D . n 
A 1 477  TRP 477  477  477 TRP TRP D . n 
A 1 478  TRP 478  478  478 TRP TRP D . n 
A 1 479  GLU 479  479  479 GLU GLU D . n 
A 1 480  MET 480  480  480 MET MET D . n 
A 1 481  LYS 481  481  481 LYS LYS D . n 
A 1 482  ARG 482  482  482 ARG ARG D . n 
A 1 483  GLU 483  483  483 GLU GLU D . n 
A 1 484  ILE 484  484  484 ILE ILE D . n 
A 1 485  VAL 485  485  485 VAL VAL D . n 
A 1 486  GLY 486  486  486 GLY GLY D . n 
A 1 487  VAL 487  487  487 VAL VAL D . n 
A 1 488  VAL 488  488  488 VAL VAL D . n 
A 1 489  GLU 489  489  489 GLU GLU D . n 
A 1 490  PRO 490  490  490 PRO PRO D . n 
A 1 491  VAL 491  491  491 VAL VAL D . n 
A 1 492  PRO 492  492  492 PRO PRO D . n 
A 1 493  HIS 493  493  493 HIS HIS D . n 
A 1 494  ASP 494  494  494 ASP ASP D . n 
A 1 495  GLU 495  495  495 GLU GLU D . n 
A 1 496  THR 496  496  496 THR THR D . n 
A 1 497  TYR 497  497  497 TYR TYR D . n 
A 1 498  CYS 498  498  498 CYS CYS D . n 
A 1 499  ASP 499  499  499 ASP ASP D . n 
A 1 500  PRO 500  500  500 PRO PRO D . n 
A 1 501  ALA 501  501  501 ALA ALA D . n 
A 1 502  SER 502  502  502 SER SER D . n 
A 1 503  LEU 503  503  503 LEU LEU D . n 
A 1 504  PHE 504  504  504 PHE PHE D . n 
A 1 505  HIS 505  505  505 HIS HIS D . n 
A 1 506  VAL 506  506  506 VAL VAL D . n 
A 1 507  SER 507  507  507 SER SER D . n 
A 1 508  ASN 508  508  508 ASN ASN D . n 
A 1 509  ASP 509  509  509 ASP ASP D . n 
A 1 510  TYR 510  510  510 TYR TYR D . n 
A 1 511  SER 511  511  511 SER SER D . n 
A 1 512  PHE 512  512  512 PHE PHE D . n 
A 1 513  ILE 513  513  513 ILE ILE D . n 
A 1 514  ARG 514  514  514 ARG ARG D . n 
A 1 515  TYR 515  515  515 TYR TYR D . n 
A 1 516  TYR 516  516  516 TYR TYR D . n 
A 1 517  THR 517  517  517 THR THR D . n 
A 1 518  ARG 518  518  518 ARG ARG D . n 
A 1 519  THR 519  519  519 THR THR D . n 
A 1 520  LEU 520  520  520 LEU LEU D . n 
A 1 521  TYR 521  521  521 TYR TYR D . n 
A 1 522  GLN 522  522  522 GLN GLN D . n 
A 1 523  PHE 523  523  523 PHE PHE D . n 
A 1 524  GLN 524  524  524 GLN GLN D . n 
A 1 525  PHE 525  525  525 PHE PHE D . n 
A 1 526  GLN 526  526  526 GLN GLN D . n 
A 1 527  GLU 527  527  527 GLU GLU D . n 
A 1 528  ALA 528  528  528 ALA ALA D . n 
A 1 529  LEU 529  529  529 LEU LEU D . n 
A 1 530  CYS 530  530  530 CYS CYS D . n 
A 1 531  GLN 531  531  531 GLN GLN D . n 
A 1 532  ALA 532  532  532 ALA ALA D . n 
A 1 533  ALA 533  533  533 ALA ALA D . n 
A 1 534  LYS 534  534  534 LYS LYS D . n 
A 1 535  HIS 535  535  535 HIS HIS D . n 
A 1 536  GLU 536  536  536 GLU GLU D . n 
A 1 537  GLY 537  537  537 GLY GLY D . n 
A 1 538  PRO 538  538  538 PRO PRO D . n 
A 1 539  LEU 539  539  539 LEU LEU D . n 
A 1 540  HIS 540  540  540 HIS HIS D . n 
A 1 541  LYS 541  541  541 LYS LYS D . n 
A 1 542  CYS 542  542  542 CYS CYS D . n 
A 1 543  ASP 543  543  543 ASP ASP D . n 
A 1 544  ILE 544  544  544 ILE ILE D . n 
A 1 545  SER 545  545  545 SER SER D . n 
A 1 546  ASN 546  546  546 ASN ASN D . n 
A 1 547  SER 547  547  547 SER SER D . n 
A 1 548  THR 548  548  548 THR THR D . n 
A 1 549  GLU 549  549  549 GLU GLU D . n 
A 1 550  ALA 550  550  550 ALA ALA D . n 
A 1 551  GLY 551  551  551 GLY GLY D . n 
A 1 552  GLN 552  552  552 GLN GLN D . n 
A 1 553  LYS 553  553  553 LYS LYS D . n 
A 1 554  LEU 554  554  554 LEU LEU D . n 
A 1 555  PHE 555  555  555 PHE PHE D . n 
A 1 556  ASN 556  556  556 ASN ASN D . n 
A 1 557  MET 557  557  557 MET MET D . n 
A 1 558  LEU 558  558  558 LEU LEU D . n 
A 1 559  ARG 559  559  559 ARG ARG D . n 
A 1 560  LEU 560  560  560 LEU LEU D . n 
A 1 561  GLY 561  561  561 GLY GLY D . n 
A 1 562  LYS 562  562  562 LYS LYS D . n 
A 1 563  SER 563  563  563 SER SER D . n 
A 1 564  GLU 564  564  564 GLU GLU D . n 
A 1 565  PRO 565  565  565 PRO PRO D . n 
A 1 566  TRP 566  566  566 TRP TRP D . n 
A 1 567  THR 567  567  567 THR THR D . n 
A 1 568  LEU 568  568  568 LEU LEU D . n 
A 1 569  ALA 569  569  569 ALA ALA D . n 
A 1 570  LEU 570  570  570 LEU LEU D . n 
A 1 571  GLU 571  571  571 GLU GLU D . n 
A 1 572  ASN 572  572  572 ASN ASN D . n 
A 1 573  VAL 573  573  573 VAL VAL D . n 
A 1 574  VAL 574  574  574 VAL VAL D . n 
A 1 575  GLY 575  575  575 GLY GLY D . n 
A 1 576  ALA 576  576  576 ALA ALA D . n 
A 1 577  LYS 577  577  577 LYS LYS D . n 
A 1 578  ASN 578  578  578 ASN ASN D . n 
A 1 579  MET 579  579  579 MET MET D . n 
A 1 580  ASN 580  580  580 ASN ASN D . n 
A 1 581  VAL 581  581  581 VAL VAL D . n 
A 1 582  ARG 582  582  582 ARG ARG D . n 
A 1 583  PRO 583  583  583 PRO PRO D . n 
A 1 584  LEU 584  584  584 LEU LEU D . n 
A 1 585  LEU 585  585  585 LEU LEU D . n 
A 1 586  ASN 586  586  586 ASN ASN D . n 
A 1 587  TYR 587  587  587 TYR TYR D . n 
A 1 588  PHE 588  588  588 PHE PHE D . n 
A 1 589  GLU 589  589  589 GLU GLU D . n 
A 1 590  PRO 590  590  590 PRO PRO D . n 
A 1 591  LEU 591  591  591 LEU LEU D . n 
A 1 592  PHE 592  592  592 PHE PHE D . n 
A 1 593  THR 593  593  593 THR THR D . n 
A 1 594  TRP 594  594  594 TRP TRP D . n 
A 1 595  LEU 595  595  595 LEU LEU D . n 
A 1 596  LYS 596  596  596 LYS LYS D . n 
A 1 597  ASP 597  597  597 ASP ASP D . n 
A 1 598  GLN 598  598  598 GLN GLN D . n 
A 1 599  ASN 599  599  599 ASN ASN D . n 
A 1 600  LYS 600  600  600 LYS LYS D . n 
A 1 601  ASN 601  601  601 ASN ASN D . n 
A 1 602  SER 602  602  602 SER SER D . n 
A 1 603  PHE 603  603  603 PHE PHE D . n 
A 1 604  VAL 604  604  604 VAL VAL D . n 
A 1 605  GLY 605  605  605 GLY GLY D . n 
A 1 606  TRP 606  606  606 TRP TRP D . n 
A 1 607  SER 607  607  607 SER SER D . n 
A 1 608  THR 608  608  608 THR THR D . n 
A 1 609  ASP 609  609  609 ASP ASP D . n 
A 1 610  TRP 610  610  610 TRP TRP D . n 
A 1 611  SER 611  611  611 SER SER D . n 
A 1 612  PRO 612  612  612 PRO PRO D . n 
A 1 613  TYR 613  613  613 TYR TYR D . n 
A 1 614  ALA 614  614  ?   ?   ?   D . n 
A 1 615  ASP 615  615  ?   ?   ?   D . n 
A 1 616  LEU 616  616  ?   ?   ?   D . n 
A 1 617  GLU 617  617  ?   ?   ?   D . n 
A 1 618  VAL 618  618  ?   ?   ?   D . n 
A 1 619  LEU 619  619  ?   ?   ?   D . n 
A 1 620  PHE 620  620  ?   ?   ?   D . n 
A 1 621  GLN 621  621  ?   ?   ?   D . n 
A 1 622  GLY 622  622  ?   ?   ?   D . n 
A 1 623  PRO 623  623  ?   ?   ?   D . n 
A 1 624  HIS 624  624  ?   ?   ?   D . n 
A 1 625  HIS 625  625  ?   ?   ?   D . n 
A 1 626  HIS 626  626  ?   ?   ?   D . n 
A 1 627  HIS 627  627  ?   ?   ?   D . n 
A 1 628  HIS 628  628  ?   ?   ?   D . n 
A 1 629  HIS 629  629  ?   ?   ?   D . n 
A 1 630  HIS 630  630  ?   ?   ?   D . n 
A 1 631  HIS 631  631  ?   ?   ?   D . n 
B 2 1    MET 1    1    ?   ?   ?   C . n 
B 2 2    PHE 2    2    ?   ?   ?   C . n 
B 2 3    VAL 3    3    ?   ?   ?   C . n 
B 2 4    PHE 4    4    ?   ?   ?   C . n 
B 2 5    LEU 5    5    ?   ?   ?   C . n 
B 2 6    VAL 6    6    ?   ?   ?   C . n 
B 2 7    LEU 7    7    ?   ?   ?   C . n 
B 2 8    LEU 8    8    ?   ?   ?   C . n 
B 2 9    PRO 9    9    ?   ?   ?   C . n 
B 2 10   LEU 10   10   ?   ?   ?   C . n 
B 2 11   VAL 11   11   ?   ?   ?   C . n 
B 2 12   SER 12   12   ?   ?   ?   C . n 
B 2 13   SER 13   13   ?   ?   ?   C . n 
B 2 14   GLN 14   14   14  GLN GLN C . n 
B 2 15   CYS 15   15   15  CYS CYS C . n 
B 2 16   VAL 16   16   16  VAL VAL C . n 
B 2 17   ASN 17   17   17  ASN ASN C . n 
B 2 18   LEU 18   18   18  LEU LEU C . n 
B 2 19   THR 19   19   19  THR THR C . n 
B 2 20   THR 20   20   20  THR THR C . n 
B 2 21   ARG 21   21   21  ARG ARG C . n 
B 2 22   THR 22   22   22  THR THR C . n 
B 2 23   GLN 23   23   23  GLN GLN C . n 
B 2 24   LEU 24   24   24  LEU LEU C . n 
B 2 25   PRO 25   25   25  PRO PRO C . n 
B 2 26   PRO 26   26   26  PRO PRO C . n 
B 2 27   ALA 27   27   27  ALA ALA C . n 
B 2 28   TYR 28   28   28  TYR TYR C . n 
B 2 29   THR 29   29   29  THR THR C . n 
B 2 30   ASN 30   30   30  ASN ASN C . n 
B 2 31   SER 31   31   31  SER SER C . n 
B 2 32   PHE 32   32   32  PHE PHE C . n 
B 2 33   THR 33   33   33  THR THR C . n 
B 2 34   ARG 34   34   34  ARG ARG C . n 
B 2 35   GLY 35   35   35  GLY GLY C . n 
B 2 36   VAL 36   36   36  VAL VAL C . n 
B 2 37   TYR 37   37   37  TYR TYR C . n 
B 2 38   TYR 38   38   38  TYR TYR C . n 
B 2 39   PRO 39   39   39  PRO PRO C . n 
B 2 40   ASP 40   40   40  ASP ASP C . n 
B 2 41   LYS 41   41   41  LYS LYS C . n 
B 2 42   VAL 42   42   42  VAL VAL C . n 
B 2 43   PHE 43   43   43  PHE PHE C . n 
B 2 44   ARG 44   44   44  ARG ARG C . n 
B 2 45   SER 45   45   45  SER SER C . n 
B 2 46   SER 46   46   46  SER SER C . n 
B 2 47   VAL 47   47   47  VAL VAL C . n 
B 2 48   LEU 48   48   48  LEU LEU C . n 
B 2 49   HIS 49   49   49  HIS HIS C . n 
B 2 50   SER 50   50   50  SER SER C . n 
B 2 51   THR 51   51   51  THR THR C . n 
B 2 52   GLN 52   52   52  GLN GLN C . n 
B 2 53   ASP 53   53   53  ASP ASP C . n 
B 2 54   LEU 54   54   54  LEU LEU C . n 
B 2 55   PHE 55   55   55  PHE PHE C . n 
B 2 56   LEU 56   56   56  LEU LEU C . n 
B 2 57   PRO 57   57   57  PRO PRO C . n 
B 2 58   PHE 58   58   58  PHE PHE C . n 
B 2 59   PHE 59   59   59  PHE PHE C . n 
B 2 60   SER 60   60   60  SER SER C . n 
B 2 61   ASN 61   61   61  ASN ASN C . n 
B 2 62   VAL 62   62   62  VAL VAL C . n 
B 2 63   THR 63   63   63  THR THR C . n 
B 2 64   TRP 64   64   64  TRP TRP C . n 
B 2 65   PHE 65   65   65  PHE PHE C . n 
B 2 66   HIS 66   66   66  HIS HIS C . n 
B 2 67   ALA 67   67   67  ALA ALA C . n 
B 2 68   ILE 68   68   68  ILE ILE C . n 
B 2 69   HIS 69   69   69  HIS HIS C . n 
B 2 70   VAL 70   70   70  VAL VAL C . n 
B 2 71   SER 71   71   71  SER SER C . n 
B 2 72   GLY 72   72   72  GLY GLY C . n 
B 2 73   THR 73   73   73  THR THR C . n 
B 2 74   ASN 74   74   ?   ?   ?   C . n 
B 2 75   GLY 75   75   ?   ?   ?   C . n 
B 2 76   THR 76   76   76  THR THR C . n 
B 2 77   LYS 77   77   77  LYS LYS C . n 
B 2 78   ARG 78   78   78  ARG ARG C . n 
B 2 79   PHE 79   79   79  PHE PHE C . n 
B 2 80   ASP 80   80   80  ASP ASP C . n 
B 2 81   ASN 81   81   81  ASN ASN C . n 
B 2 82   PRO 82   82   82  PRO PRO C . n 
B 2 83   VAL 83   83   83  VAL VAL C . n 
B 2 84   LEU 84   84   84  LEU LEU C . n 
B 2 85   PRO 85   85   85  PRO PRO C . n 
B 2 86   PHE 86   86   86  PHE PHE C . n 
B 2 87   ASN 87   87   87  ASN ASN C . n 
B 2 88   ASP 88   88   88  ASP ASP C . n 
B 2 89   GLY 89   89   89  GLY GLY C . n 
B 2 90   VAL 90   90   90  VAL VAL C . n 
B 2 91   TYR 91   91   91  TYR TYR C . n 
B 2 92   PHE 92   92   92  PHE PHE C . n 
B 2 93   ALA 93   93   93  ALA ALA C . n 
B 2 94   SER 94   94   94  SER SER C . n 
B 2 95   THR 95   95   95  THR THR C . n 
B 2 96   GLU 96   96   96  GLU GLU C . n 
B 2 97   LYS 97   97   97  LYS LYS C . n 
B 2 98   SER 98   98   98  SER SER C . n 
B 2 99   ASN 99   99   99  ASN ASN C . n 
B 2 100  ILE 100  100  100 ILE ILE C . n 
B 2 101  ILE 101  101  101 ILE ILE C . n 
B 2 102  ARG 102  102  102 ARG ARG C . n 
B 2 103  GLY 103  103  103 GLY GLY C . n 
B 2 104  TRP 104  104  104 TRP TRP C . n 
B 2 105  ILE 105  105  105 ILE ILE C . n 
B 2 106  PHE 106  106  106 PHE PHE C . n 
B 2 107  GLY 107  107  107 GLY GLY C . n 
B 2 108  THR 108  108  108 THR THR C . n 
B 2 109  THR 109  109  109 THR THR C . n 
B 2 110  LEU 110  110  110 LEU LEU C . n 
B 2 111  ASP 111  111  111 ASP ASP C . n 
B 2 112  SER 112  112  112 SER SER C . n 
B 2 113  LYS 113  113  113 LYS LYS C . n 
B 2 114  THR 114  114  114 THR THR C . n 
B 2 115  GLN 115  115  115 GLN GLN C . n 
B 2 116  SER 116  116  116 SER SER C . n 
B 2 117  LEU 117  117  117 LEU LEU C . n 
B 2 118  LEU 118  118  118 LEU LEU C . n 
B 2 119  ILE 119  119  119 ILE ILE C . n 
B 2 120  VAL 120  120  120 VAL VAL C . n 
B 2 121  ASN 121  121  121 ASN ASN C . n 
B 2 122  ASN 122  122  122 ASN ASN C . n 
B 2 123  ALA 123  123  123 ALA ALA C . n 
B 2 124  THR 124  124  124 THR THR C . n 
B 2 125  ASN 125  125  125 ASN ASN C . n 
B 2 126  VAL 126  126  126 VAL VAL C . n 
B 2 127  VAL 127  127  127 VAL VAL C . n 
B 2 128  ILE 128  128  128 ILE ILE C . n 
B 2 129  LYS 129  129  129 LYS LYS C . n 
B 2 130  VAL 130  130  130 VAL VAL C . n 
B 2 131  CYS 131  131  131 CYS CYS C . n 
B 2 132  GLU 132  132  132 GLU GLU C . n 
B 2 133  PHE 133  133  133 PHE PHE C . n 
B 2 134  GLN 134  134  134 GLN GLN C . n 
B 2 135  PHE 135  135  135 PHE PHE C . n 
B 2 136  CYS 136  136  136 CYS CYS C . n 
B 2 137  ASN 137  137  137 ASN ASN C . n 
B 2 138  ASP 138  138  138 ASP ASP C . n 
B 2 139  PRO 139  139  139 PRO PRO C . n 
B 2 140  PHE 140  140  140 PHE PHE C . n 
B 2 141  LEU 141  141  141 LEU LEU C . n 
B 2 142  GLY 142  142  142 GLY GLY C . n 
B 2 143  VAL 143  143  143 VAL VAL C . n 
B 2 144  TYR 144  144  144 TYR TYR C . n 
B 2 145  TYR 145  145  145 TYR TYR C . n 
B 2 146  HIS 146  146  146 HIS HIS C . n 
B 2 147  LYS 147  147  147 LYS LYS C . n 
B 2 148  ASN 148  148  148 ASN ASN C . n 
B 2 149  ASN 149  149  149 ASN ASN C . n 
B 2 150  LYS 150  150  150 LYS LYS C . n 
B 2 151  SER 151  151  151 SER SER C . n 
B 2 152  TRP 152  152  152 TRP TRP C . n 
B 2 153  MET 153  153  153 MET MET C . n 
B 2 154  GLU 154  154  154 GLU GLU C . n 
B 2 155  SER 155  155  155 SER SER C . n 
B 2 156  GLU 156  156  156 GLU GLU C . n 
B 2 157  PHE 157  157  157 PHE PHE C . n 
B 2 158  ARG 158  158  158 ARG ARG C . n 
B 2 159  VAL 159  159  159 VAL VAL C . n 
B 2 160  TYR 160  160  160 TYR TYR C . n 
B 2 161  SER 161  161  161 SER SER C . n 
B 2 162  SER 162  162  162 SER SER C . n 
B 2 163  ALA 163  163  163 ALA ALA C . n 
B 2 164  ASN 164  164  164 ASN ASN C . n 
B 2 165  ASN 165  165  165 ASN ASN C . n 
B 2 166  CYS 166  166  166 CYS CYS C . n 
B 2 167  THR 167  167  167 THR THR C . n 
B 2 168  PHE 168  168  168 PHE PHE C . n 
B 2 169  GLU 169  169  169 GLU GLU C . n 
B 2 170  TYR 170  170  170 TYR TYR C . n 
B 2 171  VAL 171  171  171 VAL VAL C . n 
B 2 172  SER 172  172  172 SER SER C . n 
B 2 173  GLN 173  173  173 GLN GLN C . n 
B 2 174  PRO 174  174  174 PRO PRO C . n 
B 2 175  PHE 175  175  175 PHE PHE C . n 
B 2 176  LEU 176  176  176 LEU LEU C . n 
B 2 177  MET 177  177  177 MET MET C . n 
B 2 178  ASP 178  178  178 ASP ASP C . n 
B 2 179  LEU 179  179  179 LEU LEU C . n 
B 2 180  GLU 180  180  180 GLU GLU C . n 
B 2 181  GLY 181  181  181 GLY GLY C . n 
B 2 182  LYS 182  182  182 LYS LYS C . n 
B 2 183  GLN 183  183  183 GLN GLN C . n 
B 2 184  GLY 184  184  184 GLY GLY C . n 
B 2 185  ASN 185  185  185 ASN ASN C . n 
B 2 186  PHE 186  186  186 PHE PHE C . n 
B 2 187  LYS 187  187  187 LYS LYS C . n 
B 2 188  ASN 188  188  188 ASN ASN C . n 
B 2 189  LEU 189  189  189 LEU LEU C . n 
B 2 190  ARG 190  190  190 ARG ARG C . n 
B 2 191  GLU 191  191  191 GLU GLU C . n 
B 2 192  PHE 192  192  192 PHE PHE C . n 
B 2 193  VAL 193  193  193 VAL VAL C . n 
B 2 194  PHE 194  194  194 PHE PHE C . n 
B 2 195  LYS 195  195  195 LYS LYS C . n 
B 2 196  ASN 196  196  196 ASN ASN C . n 
B 2 197  ILE 197  197  197 ILE ILE C . n 
B 2 198  ASP 198  198  198 ASP ASP C . n 
B 2 199  GLY 199  199  199 GLY GLY C . n 
B 2 200  TYR 200  200  200 TYR TYR C . n 
B 2 201  PHE 201  201  201 PHE PHE C . n 
B 2 202  LYS 202  202  202 LYS LYS C . n 
B 2 203  ILE 203  203  203 ILE ILE C . n 
B 2 204  TYR 204  204  204 TYR TYR C . n 
B 2 205  SER 205  205  205 SER SER C . n 
B 2 206  LYS 206  206  206 LYS LYS C . n 
B 2 207  HIS 207  207  207 HIS HIS C . n 
B 2 208  THR 208  208  208 THR THR C . n 
B 2 209  PRO 209  209  209 PRO PRO C . n 
B 2 210  ILE 210  210  210 ILE ILE C . n 
B 2 211  ASN 211  211  211 ASN ASN C . n 
B 2 212  LEU 212  212  212 LEU LEU C . n 
B 2 213  VAL 213  213  213 VAL VAL C . n 
B 2 214  ARG 214  214  214 ARG ARG C . n 
B 2 215  ASP 215  215  215 ASP ASP C . n 
B 2 216  LEU 216  216  216 LEU LEU C . n 
B 2 217  PRO 217  217  217 PRO PRO C . n 
B 2 218  GLN 218  218  218 GLN GLN C . n 
B 2 219  GLY 219  219  219 GLY GLY C . n 
B 2 220  PHE 220  220  220 PHE PHE C . n 
B 2 221  SER 221  221  221 SER SER C . n 
B 2 222  ALA 222  222  222 ALA ALA C . n 
B 2 223  LEU 223  223  223 LEU LEU C . n 
B 2 224  GLU 224  224  224 GLU GLU C . n 
B 2 225  PRO 225  225  225 PRO PRO C . n 
B 2 226  LEU 226  226  226 LEU LEU C . n 
B 2 227  VAL 227  227  227 VAL VAL C . n 
B 2 228  ASP 228  228  228 ASP ASP C . n 
B 2 229  LEU 229  229  229 LEU LEU C . n 
B 2 230  PRO 230  230  230 PRO PRO C . n 
B 2 231  ILE 231  231  231 ILE ILE C . n 
B 2 232  GLY 232  232  232 GLY GLY C . n 
B 2 233  ILE 233  233  233 ILE ILE C . n 
B 2 234  ASN 234  234  234 ASN ASN C . n 
B 2 235  ILE 235  235  235 ILE ILE C . n 
B 2 236  THR 236  236  236 THR THR C . n 
B 2 237  ARG 237  237  237 ARG ARG C . n 
B 2 238  PHE 238  238  238 PHE PHE C . n 
B 2 239  GLN 239  239  239 GLN GLN C . n 
B 2 240  THR 240  240  240 THR THR C . n 
B 2 241  LEU 241  241  241 LEU LEU C . n 
B 2 242  LEU 242  242  242 LEU LEU C . n 
B 2 243  ALA 243  243  243 ALA ALA C . n 
B 2 244  LEU 244  244  244 LEU LEU C . n 
B 2 245  HIS 245  245  245 HIS HIS C . n 
B 2 246  ARG 246  246  246 ARG ARG C . n 
B 2 247  SER 247  247  247 SER SER C . n 
B 2 248  TYR 248  248  248 TYR TYR C . n 
B 2 249  LEU 249  249  249 LEU LEU C . n 
B 2 250  THR 250  250  250 THR THR C . n 
B 2 251  PRO 251  251  251 PRO PRO C . n 
B 2 252  GLY 252  252  252 GLY GLY C . n 
B 2 253  ASP 253  253  253 ASP ASP C . n 
B 2 254  SER 254  254  254 SER SER C . n 
B 2 255  SER 255  255  255 SER SER C . n 
B 2 256  SER 256  256  256 SER SER C . n 
B 2 257  GLY 257  257  257 GLY GLY C . n 
B 2 258  TRP 258  258  258 TRP TRP C . n 
B 2 259  THR 259  259  259 THR THR C . n 
B 2 260  ALA 260  260  260 ALA ALA C . n 
B 2 261  GLY 261  261  261 GLY GLY C . n 
B 2 262  ALA 262  262  262 ALA ALA C . n 
B 2 263  ALA 263  263  263 ALA ALA C . n 
B 2 264  ALA 264  264  264 ALA ALA C . n 
B 2 265  TYR 265  265  265 TYR TYR C . n 
B 2 266  TYR 266  266  266 TYR TYR C . n 
B 2 267  VAL 267  267  267 VAL VAL C . n 
B 2 268  GLY 268  268  268 GLY GLY C . n 
B 2 269  TYR 269  269  269 TYR TYR C . n 
B 2 270  LEU 270  270  270 LEU LEU C . n 
B 2 271  GLN 271  271  271 GLN GLN C . n 
B 2 272  PRO 272  272  272 PRO PRO C . n 
B 2 273  ARG 273  273  273 ARG ARG C . n 
B 2 274  THR 274  274  274 THR THR C . n 
B 2 275  PHE 275  275  275 PHE PHE C . n 
B 2 276  LEU 276  276  276 LEU LEU C . n 
B 2 277  LEU 277  277  277 LEU LEU C . n 
B 2 278  LYS 278  278  278 LYS LYS C . n 
B 2 279  TYR 279  279  279 TYR TYR C . n 
B 2 280  ASN 280  280  280 ASN ASN C . n 
B 2 281  GLU 281  281  281 GLU GLU C . n 
B 2 282  ASN 282  282  282 ASN ASN C . n 
B 2 283  GLY 283  283  283 GLY GLY C . n 
B 2 284  THR 284  284  284 THR THR C . n 
B 2 285  ILE 285  285  285 ILE ILE C . n 
B 2 286  THR 286  286  286 THR THR C . n 
B 2 287  ASP 287  287  287 ASP ASP C . n 
B 2 288  ALA 288  288  288 ALA ALA C . n 
B 2 289  VAL 289  289  289 VAL VAL C . n 
B 2 290  ASP 290  290  290 ASP ASP C . n 
B 2 291  CYS 291  291  291 CYS CYS C . n 
B 2 292  ALA 292  292  292 ALA ALA C . n 
B 2 293  LEU 293  293  ?   ?   ?   C . n 
B 2 294  ASP 294  294  ?   ?   ?   C . n 
B 2 295  PRO 295  295  ?   ?   ?   C . n 
B 2 296  LEU 296  296  ?   ?   ?   C . n 
B 2 297  SER 297  297  ?   ?   ?   C . n 
B 2 298  GLU 298  298  ?   ?   ?   C . n 
B 2 299  THR 299  299  ?   ?   ?   C . n 
B 2 300  LYS 300  300  ?   ?   ?   C . n 
B 2 301  CYS 301  301  ?   ?   ?   C . n 
B 2 302  THR 302  302  ?   ?   ?   C . n 
B 2 303  LEU 303  303  ?   ?   ?   C . n 
B 2 304  LYS 304  304  ?   ?   ?   C . n 
B 2 305  SER 305  305  ?   ?   ?   C . n 
B 2 306  PHE 306  306  ?   ?   ?   C . n 
B 2 307  THR 307  307  ?   ?   ?   C . n 
B 2 308  VAL 308  308  ?   ?   ?   C . n 
B 2 309  GLU 309  309  ?   ?   ?   C . n 
B 2 310  LYS 310  310  ?   ?   ?   C . n 
B 2 311  GLY 311  311  ?   ?   ?   C . n 
B 2 312  ILE 312  312  ?   ?   ?   C . n 
B 2 313  TYR 313  313  ?   ?   ?   C . n 
B 2 314  GLN 314  314  ?   ?   ?   C . n 
B 2 315  THR 315  315  ?   ?   ?   C . n 
B 2 316  SER 316  316  ?   ?   ?   C . n 
B 2 317  ASN 317  317  ?   ?   ?   C . n 
B 2 318  PHE 318  318  ?   ?   ?   C . n 
B 2 319  ARG 319  319  ?   ?   ?   C . n 
B 2 320  VAL 320  320  ?   ?   ?   C . n 
B 2 321  GLN 321  321  ?   ?   ?   C . n 
B 2 322  PRO 322  322  ?   ?   ?   C . n 
B 2 323  THR 323  323  ?   ?   ?   C . n 
B 2 324  GLU 324  324  ?   ?   ?   C . n 
B 2 325  SER 325  325  ?   ?   ?   C . n 
B 2 326  ILE 326  326  ?   ?   ?   C . n 
B 2 327  VAL 327  327  ?   ?   ?   C . n 
B 2 328  ARG 328  328  ?   ?   ?   C . n 
B 2 329  PHE 329  329  ?   ?   ?   C . n 
B 2 330  PRO 330  330  ?   ?   ?   C . n 
B 2 331  ASN 331  331  ?   ?   ?   C . n 
B 2 332  ILE 332  332  ?   ?   ?   C . n 
B 2 333  THR 333  333  ?   ?   ?   C . n 
B 2 334  ASN 334  334  ?   ?   ?   C . n 
B 2 335  LEU 335  335  ?   ?   ?   C . n 
B 2 336  CYS 336  336  ?   ?   ?   C . n 
B 2 337  PRO 337  337  ?   ?   ?   C . n 
B 2 338  PHE 338  338  ?   ?   ?   C . n 
B 2 339  GLY 339  339  ?   ?   ?   C . n 
B 2 340  GLU 340  340  ?   ?   ?   C . n 
B 2 341  VAL 341  341  ?   ?   ?   C . n 
B 2 342  PHE 342  342  ?   ?   ?   C . n 
B 2 343  ASN 343  343  ?   ?   ?   C . n 
B 2 344  ALA 344  344  ?   ?   ?   C . n 
B 2 345  THR 345  345  ?   ?   ?   C . n 
B 2 346  ARG 346  346  ?   ?   ?   C . n 
B 2 347  PHE 347  347  ?   ?   ?   C . n 
B 2 348  ALA 348  348  ?   ?   ?   C . n 
B 2 349  SER 349  349  ?   ?   ?   C . n 
B 2 350  VAL 350  350  ?   ?   ?   C . n 
B 2 351  TYR 351  351  ?   ?   ?   C . n 
B 2 352  ALA 352  352  ?   ?   ?   C . n 
B 2 353  TRP 353  353  ?   ?   ?   C . n 
B 2 354  ASN 354  354  ?   ?   ?   C . n 
B 2 355  ARG 355  355  ?   ?   ?   C . n 
B 2 356  LYS 356  356  ?   ?   ?   C . n 
B 2 357  ARG 357  357  ?   ?   ?   C . n 
B 2 358  ILE 358  358  ?   ?   ?   C . n 
B 2 359  SER 359  359  ?   ?   ?   C . n 
B 2 360  ASN 360  360  ?   ?   ?   C . n 
B 2 361  CYS 361  361  ?   ?   ?   C . n 
B 2 362  VAL 362  362  ?   ?   ?   C . n 
B 2 363  ALA 363  363  ?   ?   ?   C . n 
B 2 364  ASP 364  364  ?   ?   ?   C . n 
B 2 365  TYR 365  365  ?   ?   ?   C . n 
B 2 366  SER 366  366  ?   ?   ?   C . n 
B 2 367  VAL 367  367  ?   ?   ?   C . n 
B 2 368  LEU 368  368  ?   ?   ?   C . n 
B 2 369  TYR 369  369  ?   ?   ?   C . n 
B 2 370  ASN 370  370  ?   ?   ?   C . n 
B 2 371  SER 371  371  ?   ?   ?   C . n 
B 2 372  ALA 372  372  ?   ?   ?   C . n 
B 2 373  SER 373  373  ?   ?   ?   C . n 
B 2 374  PHE 374  374  ?   ?   ?   C . n 
B 2 375  SER 375  375  ?   ?   ?   C . n 
B 2 376  THR 376  376  ?   ?   ?   C . n 
B 2 377  PHE 377  377  ?   ?   ?   C . n 
B 2 378  LYS 378  378  ?   ?   ?   C . n 
B 2 379  CYS 379  379  ?   ?   ?   C . n 
B 2 380  TYR 380  380  ?   ?   ?   C . n 
B 2 381  GLY 381  381  ?   ?   ?   C . n 
B 2 382  VAL 382  382  ?   ?   ?   C . n 
B 2 383  SER 383  383  ?   ?   ?   C . n 
B 2 384  PRO 384  384  ?   ?   ?   C . n 
B 2 385  THR 385  385  ?   ?   ?   C . n 
B 2 386  LYS 386  386  ?   ?   ?   C . n 
B 2 387  LEU 387  387  ?   ?   ?   C . n 
B 2 388  ASN 388  388  ?   ?   ?   C . n 
B 2 389  ASP 389  389  ?   ?   ?   C . n 
B 2 390  LEU 390  390  ?   ?   ?   C . n 
B 2 391  CYS 391  391  ?   ?   ?   C . n 
B 2 392  PHE 392  392  ?   ?   ?   C . n 
B 2 393  THR 393  393  ?   ?   ?   C . n 
B 2 394  ASN 394  394  ?   ?   ?   C . n 
B 2 395  VAL 395  395  ?   ?   ?   C . n 
B 2 396  TYR 396  396  ?   ?   ?   C . n 
B 2 397  ALA 397  397  ?   ?   ?   C . n 
B 2 398  ASP 398  398  ?   ?   ?   C . n 
B 2 399  SER 399  399  ?   ?   ?   C . n 
B 2 400  PHE 400  400  ?   ?   ?   C . n 
B 2 401  VAL 401  401  ?   ?   ?   C . n 
B 2 402  ILE 402  402  ?   ?   ?   C . n 
B 2 403  ARG 403  403  ?   ?   ?   C . n 
B 2 404  GLY 404  404  ?   ?   ?   C . n 
B 2 405  ASP 405  405  ?   ?   ?   C . n 
B 2 406  GLU 406  406  ?   ?   ?   C . n 
B 2 407  VAL 407  407  ?   ?   ?   C . n 
B 2 408  ARG 408  408  ?   ?   ?   C . n 
B 2 409  GLN 409  409  ?   ?   ?   C . n 
B 2 410  ILE 410  410  ?   ?   ?   C . n 
B 2 411  ALA 411  411  ?   ?   ?   C . n 
B 2 412  PRO 412  412  ?   ?   ?   C . n 
B 2 413  GLY 413  413  ?   ?   ?   C . n 
B 2 414  GLN 414  414  ?   ?   ?   C . n 
B 2 415  THR 415  415  ?   ?   ?   C . n 
B 2 416  GLY 416  416  ?   ?   ?   C . n 
B 2 417  LYS 417  417  ?   ?   ?   C . n 
B 2 418  ILE 418  418  ?   ?   ?   C . n 
B 2 419  ALA 419  419  ?   ?   ?   C . n 
B 2 420  ASP 420  420  ?   ?   ?   C . n 
B 2 421  TYR 421  421  ?   ?   ?   C . n 
B 2 422  ASN 422  422  ?   ?   ?   C . n 
B 2 423  TYR 423  423  ?   ?   ?   C . n 
B 2 424  LYS 424  424  ?   ?   ?   C . n 
B 2 425  LEU 425  425  ?   ?   ?   C . n 
B 2 426  PRO 426  426  ?   ?   ?   C . n 
B 2 427  ASP 427  427  ?   ?   ?   C . n 
B 2 428  ASP 428  428  ?   ?   ?   C . n 
B 2 429  PHE 429  429  ?   ?   ?   C . n 
B 2 430  THR 430  430  ?   ?   ?   C . n 
B 2 431  GLY 431  431  ?   ?   ?   C . n 
B 2 432  CYS 432  432  ?   ?   ?   C . n 
B 2 433  VAL 433  433  ?   ?   ?   C . n 
B 2 434  ILE 434  434  ?   ?   ?   C . n 
B 2 435  ALA 435  435  ?   ?   ?   C . n 
B 2 436  TRP 436  436  ?   ?   ?   C . n 
B 2 437  ASN 437  437  ?   ?   ?   C . n 
B 2 438  SER 438  438  ?   ?   ?   C . n 
B 2 439  ASN 439  439  ?   ?   ?   C . n 
B 2 440  ASN 440  440  ?   ?   ?   C . n 
B 2 441  LEU 441  441  ?   ?   ?   C . n 
B 2 442  ASP 442  442  ?   ?   ?   C . n 
B 2 443  SER 443  443  ?   ?   ?   C . n 
B 2 444  LYS 444  444  ?   ?   ?   C . n 
B 2 445  VAL 445  445  ?   ?   ?   C . n 
B 2 446  GLY 446  446  ?   ?   ?   C . n 
B 2 447  GLY 447  447  ?   ?   ?   C . n 
B 2 448  ASN 448  448  ?   ?   ?   C . n 
B 2 449  TYR 449  449  ?   ?   ?   C . n 
B 2 450  ASN 450  450  ?   ?   ?   C . n 
B 2 451  TYR 451  451  ?   ?   ?   C . n 
B 2 452  LEU 452  452  ?   ?   ?   C . n 
B 2 453  TYR 453  453  ?   ?   ?   C . n 
B 2 454  ARG 454  454  ?   ?   ?   C . n 
B 2 455  LEU 455  455  ?   ?   ?   C . n 
B 2 456  PHE 456  456  ?   ?   ?   C . n 
B 2 457  ARG 457  457  ?   ?   ?   C . n 
B 2 458  LYS 458  458  ?   ?   ?   C . n 
B 2 459  SER 459  459  ?   ?   ?   C . n 
B 2 460  ASN 460  460  ?   ?   ?   C . n 
B 2 461  LEU 461  461  ?   ?   ?   C . n 
B 2 462  LYS 462  462  ?   ?   ?   C . n 
B 2 463  PRO 463  463  ?   ?   ?   C . n 
B 2 464  PHE 464  464  ?   ?   ?   C . n 
B 2 465  GLU 465  465  ?   ?   ?   C . n 
B 2 466  ARG 466  466  ?   ?   ?   C . n 
B 2 467  ASP 467  467  ?   ?   ?   C . n 
B 2 468  ILE 468  468  ?   ?   ?   C . n 
B 2 469  SER 469  469  ?   ?   ?   C . n 
B 2 470  THR 470  470  ?   ?   ?   C . n 
B 2 471  GLU 471  471  ?   ?   ?   C . n 
B 2 472  ILE 472  472  ?   ?   ?   C . n 
B 2 473  TYR 473  473  ?   ?   ?   C . n 
B 2 474  GLN 474  474  ?   ?   ?   C . n 
B 2 475  ALA 475  475  ?   ?   ?   C . n 
B 2 476  GLY 476  476  ?   ?   ?   C . n 
B 2 477  SER 477  477  ?   ?   ?   C . n 
B 2 478  THR 478  478  ?   ?   ?   C . n 
B 2 479  PRO 479  479  ?   ?   ?   C . n 
B 2 480  CYS 480  480  ?   ?   ?   C . n 
B 2 481  ASN 481  481  ?   ?   ?   C . n 
B 2 482  GLY 482  482  ?   ?   ?   C . n 
B 2 483  VAL 483  483  ?   ?   ?   C . n 
B 2 484  GLU 484  484  ?   ?   ?   C . n 
B 2 485  GLY 485  485  ?   ?   ?   C . n 
B 2 486  PHE 486  486  ?   ?   ?   C . n 
B 2 487  ASN 487  487  ?   ?   ?   C . n 
B 2 488  CYS 488  488  ?   ?   ?   C . n 
B 2 489  TYR 489  489  ?   ?   ?   C . n 
B 2 490  PHE 490  490  ?   ?   ?   C . n 
B 2 491  PRO 491  491  ?   ?   ?   C . n 
B 2 492  LEU 492  492  ?   ?   ?   C . n 
B 2 493  GLN 493  493  ?   ?   ?   C . n 
B 2 494  SER 494  494  ?   ?   ?   C . n 
B 2 495  TYR 495  495  ?   ?   ?   C . n 
B 2 496  GLY 496  496  ?   ?   ?   C . n 
B 2 497  PHE 497  497  ?   ?   ?   C . n 
B 2 498  GLN 498  498  ?   ?   ?   C . n 
B 2 499  PRO 499  499  ?   ?   ?   C . n 
B 2 500  THR 500  500  ?   ?   ?   C . n 
B 2 501  ASN 501  501  ?   ?   ?   C . n 
B 2 502  GLY 502  502  ?   ?   ?   C . n 
B 2 503  VAL 503  503  ?   ?   ?   C . n 
B 2 504  GLY 504  504  ?   ?   ?   C . n 
B 2 505  TYR 505  505  ?   ?   ?   C . n 
B 2 506  GLN 506  506  ?   ?   ?   C . n 
B 2 507  PRO 507  507  ?   ?   ?   C . n 
B 2 508  TYR 508  508  ?   ?   ?   C . n 
B 2 509  ARG 509  509  ?   ?   ?   C . n 
B 2 510  VAL 510  510  ?   ?   ?   C . n 
B 2 511  VAL 511  511  ?   ?   ?   C . n 
B 2 512  VAL 512  512  ?   ?   ?   C . n 
B 2 513  LEU 513  513  ?   ?   ?   C . n 
B 2 514  SER 514  514  ?   ?   ?   C . n 
B 2 515  PHE 515  515  ?   ?   ?   C . n 
B 2 516  GLU 516  516  ?   ?   ?   C . n 
B 2 517  LEU 517  517  ?   ?   ?   C . n 
B 2 518  LEU 518  518  ?   ?   ?   C . n 
B 2 519  HIS 519  519  ?   ?   ?   C . n 
B 2 520  ALA 520  520  ?   ?   ?   C . n 
B 2 521  PRO 521  521  ?   ?   ?   C . n 
B 2 522  ALA 522  522  ?   ?   ?   C . n 
B 2 523  THR 523  523  ?   ?   ?   C . n 
B 2 524  VAL 524  524  ?   ?   ?   C . n 
B 2 525  CYS 525  525  ?   ?   ?   C . n 
B 2 526  GLY 526  526  ?   ?   ?   C . n 
B 2 527  PRO 527  527  ?   ?   ?   C . n 
B 2 528  LYS 528  528  ?   ?   ?   C . n 
B 2 529  LYS 529  529  ?   ?   ?   C . n 
B 2 530  SER 530  530  ?   ?   ?   C . n 
B 2 531  THR 531  531  ?   ?   ?   C . n 
B 2 532  ASN 532  532  ?   ?   ?   C . n 
B 2 533  LEU 533  533  ?   ?   ?   C . n 
B 2 534  VAL 534  534  ?   ?   ?   C . n 
B 2 535  LYS 535  535  ?   ?   ?   C . n 
B 2 536  ASN 536  536  ?   ?   ?   C . n 
B 2 537  LYS 537  537  ?   ?   ?   C . n 
B 2 538  CYS 538  538  ?   ?   ?   C . n 
B 2 539  VAL 539  539  ?   ?   ?   C . n 
B 2 540  ASN 540  540  ?   ?   ?   C . n 
B 2 541  PHE 541  541  ?   ?   ?   C . n 
B 2 542  ASN 542  542  ?   ?   ?   C . n 
B 2 543  PHE 543  543  ?   ?   ?   C . n 
B 2 544  ASN 544  544  ?   ?   ?   C . n 
B 2 545  GLY 545  545  ?   ?   ?   C . n 
B 2 546  LEU 546  546  ?   ?   ?   C . n 
B 2 547  THR 547  547  ?   ?   ?   C . n 
B 2 548  GLY 548  548  ?   ?   ?   C . n 
B 2 549  THR 549  549  ?   ?   ?   C . n 
B 2 550  GLY 550  550  ?   ?   ?   C . n 
B 2 551  VAL 551  551  ?   ?   ?   C . n 
B 2 552  LEU 552  552  ?   ?   ?   C . n 
B 2 553  THR 553  553  ?   ?   ?   C . n 
B 2 554  GLU 554  554  ?   ?   ?   C . n 
B 2 555  SER 555  555  ?   ?   ?   C . n 
B 2 556  ASN 556  556  ?   ?   ?   C . n 
B 2 557  LYS 557  557  ?   ?   ?   C . n 
B 2 558  LYS 558  558  ?   ?   ?   C . n 
B 2 559  PHE 559  559  ?   ?   ?   C . n 
B 2 560  LEU 560  560  ?   ?   ?   C . n 
B 2 561  PRO 561  561  ?   ?   ?   C . n 
B 2 562  PHE 562  562  ?   ?   ?   C . n 
B 2 563  GLN 563  563  ?   ?   ?   C . n 
B 2 564  GLN 564  564  ?   ?   ?   C . n 
B 2 565  PHE 565  565  ?   ?   ?   C . n 
B 2 566  GLY 566  566  ?   ?   ?   C . n 
B 2 567  ARG 567  567  ?   ?   ?   C . n 
B 2 568  ASP 568  568  ?   ?   ?   C . n 
B 2 569  ILE 569  569  ?   ?   ?   C . n 
B 2 570  ALA 570  570  ?   ?   ?   C . n 
B 2 571  ASP 571  571  ?   ?   ?   C . n 
B 2 572  THR 572  572  ?   ?   ?   C . n 
B 2 573  THR 573  573  ?   ?   ?   C . n 
B 2 574  ASP 574  574  ?   ?   ?   C . n 
B 2 575  ALA 575  575  ?   ?   ?   C . n 
B 2 576  VAL 576  576  ?   ?   ?   C . n 
B 2 577  ARG 577  577  ?   ?   ?   C . n 
B 2 578  ASP 578  578  ?   ?   ?   C . n 
B 2 579  PRO 579  579  ?   ?   ?   C . n 
B 2 580  GLN 580  580  ?   ?   ?   C . n 
B 2 581  THR 581  581  ?   ?   ?   C . n 
B 2 582  LEU 582  582  ?   ?   ?   C . n 
B 2 583  GLU 583  583  ?   ?   ?   C . n 
B 2 584  ILE 584  584  ?   ?   ?   C . n 
B 2 585  LEU 585  585  ?   ?   ?   C . n 
B 2 586  ASP 586  586  ?   ?   ?   C . n 
B 2 587  ILE 587  587  ?   ?   ?   C . n 
B 2 588  THR 588  588  ?   ?   ?   C . n 
B 2 589  PRO 589  589  ?   ?   ?   C . n 
B 2 590  CYS 590  590  ?   ?   ?   C . n 
B 2 591  SER 591  591  ?   ?   ?   C . n 
B 2 592  PHE 592  592  ?   ?   ?   C . n 
B 2 593  GLY 593  593  ?   ?   ?   C . n 
B 2 594  GLY 594  594  ?   ?   ?   C . n 
B 2 595  VAL 595  595  ?   ?   ?   C . n 
B 2 596  SER 596  596  ?   ?   ?   C . n 
B 2 597  VAL 597  597  ?   ?   ?   C . n 
B 2 598  ILE 598  598  ?   ?   ?   C . n 
B 2 599  THR 599  599  ?   ?   ?   C . n 
B 2 600  PRO 600  600  ?   ?   ?   C . n 
B 2 601  GLY 601  601  ?   ?   ?   C . n 
B 2 602  THR 602  602  ?   ?   ?   C . n 
B 2 603  ASN 603  603  ?   ?   ?   C . n 
B 2 604  THR 604  604  ?   ?   ?   C . n 
B 2 605  SER 605  605  ?   ?   ?   C . n 
B 2 606  ASN 606  606  ?   ?   ?   C . n 
B 2 607  GLN 607  607  ?   ?   ?   C . n 
B 2 608  VAL 608  608  ?   ?   ?   C . n 
B 2 609  ALA 609  609  ?   ?   ?   C . n 
B 2 610  VAL 610  610  ?   ?   ?   C . n 
B 2 611  LEU 611  611  ?   ?   ?   C . n 
B 2 612  TYR 612  612  ?   ?   ?   C . n 
B 2 613  GLN 613  613  ?   ?   ?   C . n 
B 2 614  GLY 614  614  ?   ?   ?   C . n 
B 2 615  VAL 615  615  ?   ?   ?   C . n 
B 2 616  ASN 616  616  ?   ?   ?   C . n 
B 2 617  CYS 617  617  ?   ?   ?   C . n 
B 2 618  THR 618  618  ?   ?   ?   C . n 
B 2 619  GLU 619  619  ?   ?   ?   C . n 
B 2 620  VAL 620  620  ?   ?   ?   C . n 
B 2 621  PRO 621  621  ?   ?   ?   C . n 
B 2 622  VAL 622  622  ?   ?   ?   C . n 
B 2 623  ALA 623  623  ?   ?   ?   C . n 
B 2 624  ILE 624  624  ?   ?   ?   C . n 
B 2 625  HIS 625  625  ?   ?   ?   C . n 
B 2 626  ALA 626  626  ?   ?   ?   C . n 
B 2 627  ASP 627  627  ?   ?   ?   C . n 
B 2 628  GLN 628  628  ?   ?   ?   C . n 
B 2 629  LEU 629  629  ?   ?   ?   C . n 
B 2 630  THR 630  630  ?   ?   ?   C . n 
B 2 631  PRO 631  631  ?   ?   ?   C . n 
B 2 632  THR 632  632  ?   ?   ?   C . n 
B 2 633  TRP 633  633  ?   ?   ?   C . n 
B 2 634  ARG 634  634  ?   ?   ?   C . n 
B 2 635  VAL 635  635  ?   ?   ?   C . n 
B 2 636  TYR 636  636  ?   ?   ?   C . n 
B 2 637  SER 637  637  ?   ?   ?   C . n 
B 2 638  THR 638  638  ?   ?   ?   C . n 
B 2 639  GLY 639  639  ?   ?   ?   C . n 
B 2 640  SER 640  640  ?   ?   ?   C . n 
B 2 641  ASN 641  641  ?   ?   ?   C . n 
B 2 642  VAL 642  642  ?   ?   ?   C . n 
B 2 643  PHE 643  643  ?   ?   ?   C . n 
B 2 644  GLN 644  644  ?   ?   ?   C . n 
B 2 645  THR 645  645  ?   ?   ?   C . n 
B 2 646  ARG 646  646  ?   ?   ?   C . n 
B 2 647  ALA 647  647  ?   ?   ?   C . n 
B 2 648  GLY 648  648  ?   ?   ?   C . n 
B 2 649  CYS 649  649  ?   ?   ?   C . n 
B 2 650  LEU 650  650  ?   ?   ?   C . n 
B 2 651  ILE 651  651  ?   ?   ?   C . n 
B 2 652  GLY 652  652  ?   ?   ?   C . n 
B 2 653  ALA 653  653  ?   ?   ?   C . n 
B 2 654  GLU 654  654  ?   ?   ?   C . n 
B 2 655  HIS 655  655  ?   ?   ?   C . n 
B 2 656  VAL 656  656  ?   ?   ?   C . n 
B 2 657  ASN 657  657  ?   ?   ?   C . n 
B 2 658  ASN 658  658  ?   ?   ?   C . n 
B 2 659  SER 659  659  ?   ?   ?   C . n 
B 2 660  TYR 660  660  ?   ?   ?   C . n 
B 2 661  GLU 661  661  ?   ?   ?   C . n 
B 2 662  CYS 662  662  ?   ?   ?   C . n 
B 2 663  ASP 663  663  ?   ?   ?   C . n 
B 2 664  ILE 664  664  ?   ?   ?   C . n 
B 2 665  PRO 665  665  ?   ?   ?   C . n 
B 2 666  ILE 666  666  ?   ?   ?   C . n 
B 2 667  GLY 667  667  ?   ?   ?   C . n 
B 2 668  ALA 668  668  ?   ?   ?   C . n 
B 2 669  GLY 669  669  ?   ?   ?   C . n 
B 2 670  ILE 670  670  ?   ?   ?   C . n 
B 2 671  CYS 671  671  ?   ?   ?   C . n 
B 2 672  ALA 672  672  ?   ?   ?   C . n 
B 2 673  SER 673  673  ?   ?   ?   C . n 
B 2 674  TYR 674  674  ?   ?   ?   C . n 
B 2 675  GLN 675  675  ?   ?   ?   C . n 
B 2 676  THR 676  676  ?   ?   ?   C . n 
B 2 677  GLN 677  677  ?   ?   ?   C . n 
B 2 678  THR 678  678  ?   ?   ?   C . n 
B 2 679  ASN 679  679  ?   ?   ?   C . n 
B 2 680  SER 680  680  ?   ?   ?   C . n 
B 2 681  PRO 681  681  ?   ?   ?   C . n 
B 2 682  ARG 682  682  ?   ?   ?   C . n 
B 2 683  ARG 683  683  ?   ?   ?   C . n 
B 2 684  ALA 684  684  ?   ?   ?   C . n 
B 2 685  ARG 685  685  ?   ?   ?   C . n 
B 2 686  SER 686  686  ?   ?   ?   C . n 
B 2 687  VAL 687  687  ?   ?   ?   C . n 
B 2 688  ALA 688  688  ?   ?   ?   C . n 
B 2 689  SER 689  689  ?   ?   ?   C . n 
B 2 690  GLN 690  690  ?   ?   ?   C . n 
B 2 691  SER 691  691  ?   ?   ?   C . n 
B 2 692  ILE 692  692  ?   ?   ?   C . n 
B 2 693  ILE 693  693  ?   ?   ?   C . n 
B 2 694  ALA 694  694  ?   ?   ?   C . n 
B 2 695  TYR 695  695  ?   ?   ?   C . n 
B 2 696  THR 696  696  ?   ?   ?   C . n 
B 2 697  MET 697  697  ?   ?   ?   C . n 
B 2 698  SER 698  698  ?   ?   ?   C . n 
B 2 699  LEU 699  699  ?   ?   ?   C . n 
B 2 700  GLY 700  700  ?   ?   ?   C . n 
B 2 701  ALA 701  701  ?   ?   ?   C . n 
B 2 702  GLU 702  702  ?   ?   ?   C . n 
B 2 703  ASN 703  703  ?   ?   ?   C . n 
B 2 704  SER 704  704  ?   ?   ?   C . n 
B 2 705  VAL 705  705  ?   ?   ?   C . n 
B 2 706  ALA 706  706  ?   ?   ?   C . n 
B 2 707  TYR 707  707  ?   ?   ?   C . n 
B 2 708  SER 708  708  ?   ?   ?   C . n 
B 2 709  ASN 709  709  ?   ?   ?   C . n 
B 2 710  ASN 710  710  ?   ?   ?   C . n 
B 2 711  SER 711  711  ?   ?   ?   C . n 
B 2 712  ILE 712  712  ?   ?   ?   C . n 
B 2 713  ALA 713  713  ?   ?   ?   C . n 
B 2 714  ILE 714  714  ?   ?   ?   C . n 
B 2 715  PRO 715  715  ?   ?   ?   C . n 
B 2 716  THR 716  716  ?   ?   ?   C . n 
B 2 717  ASN 717  717  ?   ?   ?   C . n 
B 2 718  PHE 718  718  ?   ?   ?   C . n 
B 2 719  THR 719  719  ?   ?   ?   C . n 
B 2 720  ILE 720  720  ?   ?   ?   C . n 
B 2 721  SER 721  721  ?   ?   ?   C . n 
B 2 722  VAL 722  722  ?   ?   ?   C . n 
B 2 723  THR 723  723  ?   ?   ?   C . n 
B 2 724  THR 724  724  ?   ?   ?   C . n 
B 2 725  GLU 725  725  ?   ?   ?   C . n 
B 2 726  ILE 726  726  ?   ?   ?   C . n 
B 2 727  LEU 727  727  ?   ?   ?   C . n 
B 2 728  PRO 728  728  ?   ?   ?   C . n 
B 2 729  VAL 729  729  ?   ?   ?   C . n 
B 2 730  SER 730  730  ?   ?   ?   C . n 
B 2 731  MET 731  731  ?   ?   ?   C . n 
B 2 732  THR 732  732  ?   ?   ?   C . n 
B 2 733  LYS 733  733  ?   ?   ?   C . n 
B 2 734  THR 734  734  ?   ?   ?   C . n 
B 2 735  SER 735  735  ?   ?   ?   C . n 
B 2 736  VAL 736  736  ?   ?   ?   C . n 
B 2 737  ASP 737  737  ?   ?   ?   C . n 
B 2 738  CYS 738  738  ?   ?   ?   C . n 
B 2 739  THR 739  739  ?   ?   ?   C . n 
B 2 740  MET 740  740  ?   ?   ?   C . n 
B 2 741  TYR 741  741  ?   ?   ?   C . n 
B 2 742  ILE 742  742  ?   ?   ?   C . n 
B 2 743  CYS 743  743  ?   ?   ?   C . n 
B 2 744  GLY 744  744  ?   ?   ?   C . n 
B 2 745  ASP 745  745  ?   ?   ?   C . n 
B 2 746  SER 746  746  ?   ?   ?   C . n 
B 2 747  THR 747  747  ?   ?   ?   C . n 
B 2 748  GLU 748  748  ?   ?   ?   C . n 
B 2 749  CYS 749  749  ?   ?   ?   C . n 
B 2 750  SER 750  750  ?   ?   ?   C . n 
B 2 751  ASN 751  751  ?   ?   ?   C . n 
B 2 752  LEU 752  752  ?   ?   ?   C . n 
B 2 753  LEU 753  753  ?   ?   ?   C . n 
B 2 754  LEU 754  754  ?   ?   ?   C . n 
B 2 755  GLN 755  755  ?   ?   ?   C . n 
B 2 756  TYR 756  756  ?   ?   ?   C . n 
B 2 757  GLY 757  757  ?   ?   ?   C . n 
B 2 758  SER 758  758  ?   ?   ?   C . n 
B 2 759  PHE 759  759  ?   ?   ?   C . n 
B 2 760  CYS 760  760  ?   ?   ?   C . n 
B 2 761  THR 761  761  ?   ?   ?   C . n 
B 2 762  GLN 762  762  ?   ?   ?   C . n 
B 2 763  LEU 763  763  ?   ?   ?   C . n 
B 2 764  ASN 764  764  ?   ?   ?   C . n 
B 2 765  ARG 765  765  ?   ?   ?   C . n 
B 2 766  ALA 766  766  ?   ?   ?   C . n 
B 2 767  LEU 767  767  ?   ?   ?   C . n 
B 2 768  THR 768  768  ?   ?   ?   C . n 
B 2 769  GLY 769  769  ?   ?   ?   C . n 
B 2 770  ILE 770  770  ?   ?   ?   C . n 
B 2 771  ALA 771  771  ?   ?   ?   C . n 
B 2 772  VAL 772  772  ?   ?   ?   C . n 
B 2 773  GLU 773  773  ?   ?   ?   C . n 
B 2 774  GLN 774  774  ?   ?   ?   C . n 
B 2 775  ASP 775  775  ?   ?   ?   C . n 
B 2 776  LYS 776  776  ?   ?   ?   C . n 
B 2 777  ASN 777  777  ?   ?   ?   C . n 
B 2 778  THR 778  778  ?   ?   ?   C . n 
B 2 779  GLN 779  779  ?   ?   ?   C . n 
B 2 780  GLU 780  780  ?   ?   ?   C . n 
B 2 781  VAL 781  781  ?   ?   ?   C . n 
B 2 782  PHE 782  782  ?   ?   ?   C . n 
B 2 783  ALA 783  783  ?   ?   ?   C . n 
B 2 784  GLN 784  784  ?   ?   ?   C . n 
B 2 785  VAL 785  785  ?   ?   ?   C . n 
B 2 786  LYS 786  786  ?   ?   ?   C . n 
B 2 787  GLN 787  787  ?   ?   ?   C . n 
B 2 788  ILE 788  788  ?   ?   ?   C . n 
B 2 789  TYR 789  789  ?   ?   ?   C . n 
B 2 790  LYS 790  790  ?   ?   ?   C . n 
B 2 791  THR 791  791  ?   ?   ?   C . n 
B 2 792  PRO 792  792  ?   ?   ?   C . n 
B 2 793  PRO 793  793  ?   ?   ?   C . n 
B 2 794  ILE 794  794  ?   ?   ?   C . n 
B 2 795  LYS 795  795  ?   ?   ?   C . n 
B 2 796  ASP 796  796  ?   ?   ?   C . n 
B 2 797  PHE 797  797  ?   ?   ?   C . n 
B 2 798  GLY 798  798  ?   ?   ?   C . n 
B 2 799  GLY 799  799  ?   ?   ?   C . n 
B 2 800  PHE 800  800  ?   ?   ?   C . n 
B 2 801  ASN 801  801  ?   ?   ?   C . n 
B 2 802  PHE 802  802  ?   ?   ?   C . n 
B 2 803  SER 803  803  ?   ?   ?   C . n 
B 2 804  GLN 804  804  ?   ?   ?   C . n 
B 2 805  ILE 805  805  ?   ?   ?   C . n 
B 2 806  LEU 806  806  ?   ?   ?   C . n 
B 2 807  PRO 807  807  ?   ?   ?   C . n 
B 2 808  ASP 808  808  ?   ?   ?   C . n 
B 2 809  PRO 809  809  ?   ?   ?   C . n 
B 2 810  SER 810  810  ?   ?   ?   C . n 
B 2 811  LYS 811  811  ?   ?   ?   C . n 
B 2 812  PRO 812  812  ?   ?   ?   C . n 
B 2 813  SER 813  813  ?   ?   ?   C . n 
B 2 814  LYS 814  814  ?   ?   ?   C . n 
B 2 815  ARG 815  815  ?   ?   ?   C . n 
B 2 816  SER 816  816  ?   ?   ?   C . n 
B 2 817  PHE 817  817  ?   ?   ?   C . n 
B 2 818  ILE 818  818  ?   ?   ?   C . n 
B 2 819  GLU 819  819  ?   ?   ?   C . n 
B 2 820  ASP 820  820  ?   ?   ?   C . n 
B 2 821  LEU 821  821  ?   ?   ?   C . n 
B 2 822  LEU 822  822  ?   ?   ?   C . n 
B 2 823  PHE 823  823  ?   ?   ?   C . n 
B 2 824  ASN 824  824  ?   ?   ?   C . n 
B 2 825  LYS 825  825  ?   ?   ?   C . n 
B 2 826  VAL 826  826  ?   ?   ?   C . n 
B 2 827  THR 827  827  ?   ?   ?   C . n 
B 2 828  LEU 828  828  ?   ?   ?   C . n 
B 2 829  ALA 829  829  ?   ?   ?   C . n 
B 2 830  ASP 830  830  ?   ?   ?   C . n 
B 2 831  ALA 831  831  ?   ?   ?   C . n 
B 2 832  GLY 832  832  ?   ?   ?   C . n 
B 2 833  PHE 833  833  ?   ?   ?   C . n 
B 2 834  ILE 834  834  ?   ?   ?   C . n 
B 2 835  LYS 835  835  ?   ?   ?   C . n 
B 2 836  GLN 836  836  ?   ?   ?   C . n 
B 2 837  TYR 837  837  ?   ?   ?   C . n 
B 2 838  GLY 838  838  ?   ?   ?   C . n 
B 2 839  ASP 839  839  ?   ?   ?   C . n 
B 2 840  CYS 840  840  ?   ?   ?   C . n 
B 2 841  LEU 841  841  ?   ?   ?   C . n 
B 2 842  GLY 842  842  ?   ?   ?   C . n 
B 2 843  ASP 843  843  ?   ?   ?   C . n 
B 2 844  ILE 844  844  ?   ?   ?   C . n 
B 2 845  ALA 845  845  ?   ?   ?   C . n 
B 2 846  ALA 846  846  ?   ?   ?   C . n 
B 2 847  ARG 847  847  ?   ?   ?   C . n 
B 2 848  ASP 848  848  ?   ?   ?   C . n 
B 2 849  LEU 849  849  ?   ?   ?   C . n 
B 2 850  ILE 850  850  ?   ?   ?   C . n 
B 2 851  CYS 851  851  ?   ?   ?   C . n 
B 2 852  ALA 852  852  ?   ?   ?   C . n 
B 2 853  GLN 853  853  ?   ?   ?   C . n 
B 2 854  LYS 854  854  ?   ?   ?   C . n 
B 2 855  PHE 855  855  ?   ?   ?   C . n 
B 2 856  ASN 856  856  ?   ?   ?   C . n 
B 2 857  GLY 857  857  ?   ?   ?   C . n 
B 2 858  LEU 858  858  ?   ?   ?   C . n 
B 2 859  THR 859  859  ?   ?   ?   C . n 
B 2 860  VAL 860  860  ?   ?   ?   C . n 
B 2 861  LEU 861  861  ?   ?   ?   C . n 
B 2 862  PRO 862  862  ?   ?   ?   C . n 
B 2 863  PRO 863  863  ?   ?   ?   C . n 
B 2 864  LEU 864  864  ?   ?   ?   C . n 
B 2 865  LEU 865  865  ?   ?   ?   C . n 
B 2 866  THR 866  866  ?   ?   ?   C . n 
B 2 867  ASP 867  867  ?   ?   ?   C . n 
B 2 868  GLU 868  868  ?   ?   ?   C . n 
B 2 869  MET 869  869  ?   ?   ?   C . n 
B 2 870  ILE 870  870  ?   ?   ?   C . n 
B 2 871  ALA 871  871  ?   ?   ?   C . n 
B 2 872  GLN 872  872  ?   ?   ?   C . n 
B 2 873  TYR 873  873  ?   ?   ?   C . n 
B 2 874  THR 874  874  ?   ?   ?   C . n 
B 2 875  SER 875  875  ?   ?   ?   C . n 
B 2 876  ALA 876  876  ?   ?   ?   C . n 
B 2 877  LEU 877  877  ?   ?   ?   C . n 
B 2 878  LEU 878  878  ?   ?   ?   C . n 
B 2 879  ALA 879  879  ?   ?   ?   C . n 
B 2 880  GLY 880  880  ?   ?   ?   C . n 
B 2 881  THR 881  881  ?   ?   ?   C . n 
B 2 882  ILE 882  882  ?   ?   ?   C . n 
B 2 883  THR 883  883  ?   ?   ?   C . n 
B 2 884  SER 884  884  ?   ?   ?   C . n 
B 2 885  GLY 885  885  ?   ?   ?   C . n 
B 2 886  TRP 886  886  ?   ?   ?   C . n 
B 2 887  THR 887  887  ?   ?   ?   C . n 
B 2 888  PHE 888  888  ?   ?   ?   C . n 
B 2 889  GLY 889  889  ?   ?   ?   C . n 
B 2 890  ALA 890  890  ?   ?   ?   C . n 
B 2 891  GLY 891  891  ?   ?   ?   C . n 
B 2 892  ALA 892  892  ?   ?   ?   C . n 
B 2 893  ALA 893  893  ?   ?   ?   C . n 
B 2 894  LEU 894  894  ?   ?   ?   C . n 
B 2 895  GLN 895  895  ?   ?   ?   C . n 
B 2 896  ILE 896  896  ?   ?   ?   C . n 
B 2 897  PRO 897  897  ?   ?   ?   C . n 
B 2 898  PHE 898  898  ?   ?   ?   C . n 
B 2 899  ALA 899  899  ?   ?   ?   C . n 
B 2 900  MET 900  900  ?   ?   ?   C . n 
B 2 901  GLN 901  901  ?   ?   ?   C . n 
B 2 902  MET 902  902  ?   ?   ?   C . n 
B 2 903  ALA 903  903  ?   ?   ?   C . n 
B 2 904  TYR 904  904  ?   ?   ?   C . n 
B 2 905  ARG 905  905  ?   ?   ?   C . n 
B 2 906  PHE 906  906  ?   ?   ?   C . n 
B 2 907  ASN 907  907  ?   ?   ?   C . n 
B 2 908  GLY 908  908  ?   ?   ?   C . n 
B 2 909  ILE 909  909  ?   ?   ?   C . n 
B 2 910  GLY 910  910  ?   ?   ?   C . n 
B 2 911  VAL 911  911  ?   ?   ?   C . n 
B 2 912  THR 912  912  ?   ?   ?   C . n 
B 2 913  GLN 913  913  ?   ?   ?   C . n 
B 2 914  ASN 914  914  ?   ?   ?   C . n 
B 2 915  VAL 915  915  ?   ?   ?   C . n 
B 2 916  LEU 916  916  ?   ?   ?   C . n 
B 2 917  TYR 917  917  ?   ?   ?   C . n 
B 2 918  GLU 918  918  ?   ?   ?   C . n 
B 2 919  ASN 919  919  ?   ?   ?   C . n 
B 2 920  GLN 920  920  ?   ?   ?   C . n 
B 2 921  LYS 921  921  ?   ?   ?   C . n 
B 2 922  LEU 922  922  ?   ?   ?   C . n 
B 2 923  ILE 923  923  ?   ?   ?   C . n 
B 2 924  ALA 924  924  ?   ?   ?   C . n 
B 2 925  ASN 925  925  ?   ?   ?   C . n 
B 2 926  GLN 926  926  ?   ?   ?   C . n 
B 2 927  PHE 927  927  ?   ?   ?   C . n 
B 2 928  ASN 928  928  ?   ?   ?   C . n 
B 2 929  SER 929  929  ?   ?   ?   C . n 
B 2 930  ALA 930  930  ?   ?   ?   C . n 
B 2 931  ILE 931  931  ?   ?   ?   C . n 
B 2 932  GLY 932  932  ?   ?   ?   C . n 
B 2 933  LYS 933  933  ?   ?   ?   C . n 
B 2 934  ILE 934  934  ?   ?   ?   C . n 
B 2 935  GLN 935  935  ?   ?   ?   C . n 
B 2 936  ASP 936  936  ?   ?   ?   C . n 
B 2 937  SER 937  937  ?   ?   ?   C . n 
B 2 938  LEU 938  938  ?   ?   ?   C . n 
B 2 939  SER 939  939  ?   ?   ?   C . n 
B 2 940  SER 940  940  ?   ?   ?   C . n 
B 2 941  THR 941  941  ?   ?   ?   C . n 
B 2 942  ALA 942  942  ?   ?   ?   C . n 
B 2 943  SER 943  943  ?   ?   ?   C . n 
B 2 944  ALA 944  944  ?   ?   ?   C . n 
B 2 945  LEU 945  945  ?   ?   ?   C . n 
B 2 946  GLY 946  946  ?   ?   ?   C . n 
B 2 947  LYS 947  947  ?   ?   ?   C . n 
B 2 948  LEU 948  948  ?   ?   ?   C . n 
B 2 949  GLN 949  949  ?   ?   ?   C . n 
B 2 950  ASP 950  950  ?   ?   ?   C . n 
B 2 951  VAL 951  951  ?   ?   ?   C . n 
B 2 952  VAL 952  952  ?   ?   ?   C . n 
B 2 953  ASN 953  953  ?   ?   ?   C . n 
B 2 954  GLN 954  954  ?   ?   ?   C . n 
B 2 955  ASN 955  955  ?   ?   ?   C . n 
B 2 956  ALA 956  956  ?   ?   ?   C . n 
B 2 957  GLN 957  957  ?   ?   ?   C . n 
B 2 958  ALA 958  958  ?   ?   ?   C . n 
B 2 959  LEU 959  959  ?   ?   ?   C . n 
B 2 960  ASN 960  960  ?   ?   ?   C . n 
B 2 961  THR 961  961  ?   ?   ?   C . n 
B 2 962  LEU 962  962  ?   ?   ?   C . n 
B 2 963  VAL 963  963  ?   ?   ?   C . n 
B 2 964  LYS 964  964  ?   ?   ?   C . n 
B 2 965  GLN 965  965  ?   ?   ?   C . n 
B 2 966  LEU 966  966  ?   ?   ?   C . n 
B 2 967  SER 967  967  ?   ?   ?   C . n 
B 2 968  SER 968  968  ?   ?   ?   C . n 
B 2 969  ASN 969  969  ?   ?   ?   C . n 
B 2 970  PHE 970  970  ?   ?   ?   C . n 
B 2 971  GLY 971  971  ?   ?   ?   C . n 
B 2 972  ALA 972  972  ?   ?   ?   C . n 
B 2 973  ILE 973  973  ?   ?   ?   C . n 
B 2 974  SER 974  974  ?   ?   ?   C . n 
B 2 975  SER 975  975  ?   ?   ?   C . n 
B 2 976  VAL 976  976  ?   ?   ?   C . n 
B 2 977  LEU 977  977  ?   ?   ?   C . n 
B 2 978  ASN 978  978  ?   ?   ?   C . n 
B 2 979  ASP 979  979  ?   ?   ?   C . n 
B 2 980  ILE 980  980  ?   ?   ?   C . n 
B 2 981  LEU 981  981  ?   ?   ?   C . n 
B 2 982  SER 982  982  ?   ?   ?   C . n 
B 2 983  ARG 983  983  ?   ?   ?   C . n 
B 2 984  LEU 984  984  ?   ?   ?   C . n 
B 2 985  ASP 985  985  ?   ?   ?   C . n 
B 2 986  LYS 986  986  ?   ?   ?   C . n 
B 2 987  VAL 987  987  ?   ?   ?   C . n 
B 2 988  GLU 988  988  ?   ?   ?   C . n 
B 2 989  ALA 989  989  ?   ?   ?   C . n 
B 2 990  GLU 990  990  ?   ?   ?   C . n 
B 2 991  VAL 991  991  ?   ?   ?   C . n 
B 2 992  GLN 992  992  ?   ?   ?   C . n 
B 2 993  ILE 993  993  ?   ?   ?   C . n 
B 2 994  ASP 994  994  ?   ?   ?   C . n 
B 2 995  ARG 995  995  ?   ?   ?   C . n 
B 2 996  LEU 996  996  ?   ?   ?   C . n 
B 2 997  ILE 997  997  ?   ?   ?   C . n 
B 2 998  THR 998  998  ?   ?   ?   C . n 
B 2 999  GLY 999  999  ?   ?   ?   C . n 
B 2 1000 ARG 1000 1000 ?   ?   ?   C . n 
B 2 1001 LEU 1001 1001 ?   ?   ?   C . n 
B 2 1002 GLN 1002 1002 ?   ?   ?   C . n 
B 2 1003 SER 1003 1003 ?   ?   ?   C . n 
B 2 1004 LEU 1004 1004 ?   ?   ?   C . n 
B 2 1005 GLN 1005 1005 ?   ?   ?   C . n 
B 2 1006 THR 1006 1006 ?   ?   ?   C . n 
B 2 1007 TYR 1007 1007 ?   ?   ?   C . n 
B 2 1008 VAL 1008 1008 ?   ?   ?   C . n 
B 2 1009 THR 1009 1009 ?   ?   ?   C . n 
B 2 1010 GLN 1010 1010 ?   ?   ?   C . n 
B 2 1011 GLN 1011 1011 ?   ?   ?   C . n 
B 2 1012 LEU 1012 1012 ?   ?   ?   C . n 
B 2 1013 ILE 1013 1013 ?   ?   ?   C . n 
B 2 1014 ARG 1014 1014 ?   ?   ?   C . n 
B 2 1015 ALA 1015 1015 ?   ?   ?   C . n 
B 2 1016 ALA 1016 1016 ?   ?   ?   C . n 
B 2 1017 GLU 1017 1017 ?   ?   ?   C . n 
B 2 1018 ILE 1018 1018 ?   ?   ?   C . n 
B 2 1019 ARG 1019 1019 ?   ?   ?   C . n 
B 2 1020 ALA 1020 1020 ?   ?   ?   C . n 
B 2 1021 SER 1021 1021 ?   ?   ?   C . n 
B 2 1022 ALA 1022 1022 ?   ?   ?   C . n 
B 2 1023 ASN 1023 1023 ?   ?   ?   C . n 
B 2 1024 LEU 1024 1024 ?   ?   ?   C . n 
B 2 1025 ALA 1025 1025 ?   ?   ?   C . n 
B 2 1026 ALA 1026 1026 ?   ?   ?   C . n 
B 2 1027 THR 1027 1027 ?   ?   ?   C . n 
B 2 1028 LYS 1028 1028 ?   ?   ?   C . n 
B 2 1029 MET 1029 1029 ?   ?   ?   C . n 
B 2 1030 SER 1030 1030 ?   ?   ?   C . n 
B 2 1031 GLU 1031 1031 ?   ?   ?   C . n 
B 2 1032 CYS 1032 1032 ?   ?   ?   C . n 
B 2 1033 VAL 1033 1033 ?   ?   ?   C . n 
B 2 1034 LEU 1034 1034 ?   ?   ?   C . n 
B 2 1035 GLY 1035 1035 ?   ?   ?   C . n 
B 2 1036 GLN 1036 1036 ?   ?   ?   C . n 
B 2 1037 SER 1037 1037 ?   ?   ?   C . n 
B 2 1038 LYS 1038 1038 ?   ?   ?   C . n 
B 2 1039 ARG 1039 1039 ?   ?   ?   C . n 
B 2 1040 VAL 1040 1040 ?   ?   ?   C . n 
B 2 1041 ASP 1041 1041 ?   ?   ?   C . n 
B 2 1042 PHE 1042 1042 ?   ?   ?   C . n 
B 2 1043 CYS 1043 1043 ?   ?   ?   C . n 
B 2 1044 GLY 1044 1044 ?   ?   ?   C . n 
B 2 1045 LYS 1045 1045 ?   ?   ?   C . n 
B 2 1046 GLY 1046 1046 ?   ?   ?   C . n 
B 2 1047 TYR 1047 1047 ?   ?   ?   C . n 
B 2 1048 HIS 1048 1048 ?   ?   ?   C . n 
B 2 1049 LEU 1049 1049 ?   ?   ?   C . n 
B 2 1050 MET 1050 1050 ?   ?   ?   C . n 
B 2 1051 SER 1051 1051 ?   ?   ?   C . n 
B 2 1052 PHE 1052 1052 ?   ?   ?   C . n 
B 2 1053 PRO 1053 1053 ?   ?   ?   C . n 
B 2 1054 GLN 1054 1054 ?   ?   ?   C . n 
B 2 1055 SER 1055 1055 ?   ?   ?   C . n 
B 2 1056 ALA 1056 1056 ?   ?   ?   C . n 
B 2 1057 PRO 1057 1057 ?   ?   ?   C . n 
B 2 1058 HIS 1058 1058 ?   ?   ?   C . n 
B 2 1059 GLY 1059 1059 ?   ?   ?   C . n 
B 2 1060 VAL 1060 1060 ?   ?   ?   C . n 
B 2 1061 VAL 1061 1061 ?   ?   ?   C . n 
B 2 1062 PHE 1062 1062 ?   ?   ?   C . n 
B 2 1063 LEU 1063 1063 ?   ?   ?   C . n 
B 2 1064 HIS 1064 1064 ?   ?   ?   C . n 
B 2 1065 VAL 1065 1065 ?   ?   ?   C . n 
B 2 1066 THR 1066 1066 ?   ?   ?   C . n 
B 2 1067 TYR 1067 1067 ?   ?   ?   C . n 
B 2 1068 VAL 1068 1068 ?   ?   ?   C . n 
B 2 1069 PRO 1069 1069 ?   ?   ?   C . n 
B 2 1070 ALA 1070 1070 ?   ?   ?   C . n 
B 2 1071 GLN 1071 1071 ?   ?   ?   C . n 
B 2 1072 GLU 1072 1072 ?   ?   ?   C . n 
B 2 1073 LYS 1073 1073 ?   ?   ?   C . n 
B 2 1074 ASN 1074 1074 ?   ?   ?   C . n 
B 2 1075 PHE 1075 1075 ?   ?   ?   C . n 
B 2 1076 THR 1076 1076 ?   ?   ?   C . n 
B 2 1077 THR 1077 1077 ?   ?   ?   C . n 
B 2 1078 ALA 1078 1078 ?   ?   ?   C . n 
B 2 1079 PRO 1079 1079 ?   ?   ?   C . n 
B 2 1080 ALA 1080 1080 ?   ?   ?   C . n 
B 2 1081 ILE 1081 1081 ?   ?   ?   C . n 
B 2 1082 CYS 1082 1082 ?   ?   ?   C . n 
B 2 1083 HIS 1083 1083 ?   ?   ?   C . n 
B 2 1084 ASP 1084 1084 ?   ?   ?   C . n 
B 2 1085 GLY 1085 1085 ?   ?   ?   C . n 
B 2 1086 LYS 1086 1086 ?   ?   ?   C . n 
B 2 1087 ALA 1087 1087 ?   ?   ?   C . n 
B 2 1088 HIS 1088 1088 ?   ?   ?   C . n 
B 2 1089 PHE 1089 1089 ?   ?   ?   C . n 
B 2 1090 PRO 1090 1090 ?   ?   ?   C . n 
B 2 1091 ARG 1091 1091 ?   ?   ?   C . n 
B 2 1092 GLU 1092 1092 ?   ?   ?   C . n 
B 2 1093 GLY 1093 1093 ?   ?   ?   C . n 
B 2 1094 VAL 1094 1094 ?   ?   ?   C . n 
B 2 1095 PHE 1095 1095 ?   ?   ?   C . n 
B 2 1096 VAL 1096 1096 ?   ?   ?   C . n 
B 2 1097 SER 1097 1097 ?   ?   ?   C . n 
B 2 1098 ASN 1098 1098 ?   ?   ?   C . n 
B 2 1099 GLY 1099 1099 ?   ?   ?   C . n 
B 2 1100 THR 1100 1100 ?   ?   ?   C . n 
B 2 1101 HIS 1101 1101 ?   ?   ?   C . n 
B 2 1102 TRP 1102 1102 ?   ?   ?   C . n 
B 2 1103 PHE 1103 1103 ?   ?   ?   C . n 
B 2 1104 VAL 1104 1104 ?   ?   ?   C . n 
B 2 1105 THR 1105 1105 ?   ?   ?   C . n 
B 2 1106 GLN 1106 1106 ?   ?   ?   C . n 
B 2 1107 ARG 1107 1107 ?   ?   ?   C . n 
B 2 1108 ASN 1108 1108 ?   ?   ?   C . n 
B 2 1109 PHE 1109 1109 ?   ?   ?   C . n 
B 2 1110 TYR 1110 1110 ?   ?   ?   C . n 
B 2 1111 GLU 1111 1111 ?   ?   ?   C . n 
B 2 1112 PRO 1112 1112 ?   ?   ?   C . n 
B 2 1113 GLN 1113 1113 ?   ?   ?   C . n 
B 2 1114 ILE 1114 1114 ?   ?   ?   C . n 
B 2 1115 ILE 1115 1115 ?   ?   ?   C . n 
B 2 1116 THR 1116 1116 ?   ?   ?   C . n 
B 2 1117 THR 1117 1117 ?   ?   ?   C . n 
B 2 1118 ASP 1118 1118 ?   ?   ?   C . n 
B 2 1119 ASN 1119 1119 ?   ?   ?   C . n 
B 2 1120 THR 1120 1120 ?   ?   ?   C . n 
B 2 1121 PHE 1121 1121 ?   ?   ?   C . n 
B 2 1122 VAL 1122 1122 ?   ?   ?   C . n 
B 2 1123 SER 1123 1123 ?   ?   ?   C . n 
B 2 1124 GLY 1124 1124 ?   ?   ?   C . n 
B 2 1125 ASN 1125 1125 ?   ?   ?   C . n 
B 2 1126 CYS 1126 1126 ?   ?   ?   C . n 
B 2 1127 ASP 1127 1127 ?   ?   ?   C . n 
B 2 1128 VAL 1128 1128 ?   ?   ?   C . n 
B 2 1129 VAL 1129 1129 ?   ?   ?   C . n 
B 2 1130 ILE 1130 1130 ?   ?   ?   C . n 
B 2 1131 GLY 1131 1131 ?   ?   ?   C . n 
B 2 1132 ILE 1132 1132 ?   ?   ?   C . n 
B 2 1133 VAL 1133 1133 ?   ?   ?   C . n 
B 2 1134 ASN 1134 1134 ?   ?   ?   C . n 
B 2 1135 ASN 1135 1135 ?   ?   ?   C . n 
B 2 1136 THR 1136 1136 ?   ?   ?   C . n 
B 2 1137 VAL 1137 1137 ?   ?   ?   C . n 
B 2 1138 TYR 1138 1138 ?   ?   ?   C . n 
B 2 1139 ASP 1139 1139 ?   ?   ?   C . n 
B 2 1140 PRO 1140 1140 ?   ?   ?   C . n 
B 2 1141 LEU 1141 1141 ?   ?   ?   C . n 
B 2 1142 GLN 1142 1142 ?   ?   ?   C . n 
B 2 1143 PRO 1143 1143 ?   ?   ?   C . n 
B 2 1144 GLU 1144 1144 ?   ?   ?   C . n 
B 2 1145 LEU 1145 1145 ?   ?   ?   C . n 
B 2 1146 ASP 1146 1146 ?   ?   ?   C . n 
B 2 1147 SER 1147 1147 ?   ?   ?   C . n 
B 2 1148 PHE 1148 1148 ?   ?   ?   C . n 
B 2 1149 LYS 1149 1149 ?   ?   ?   C . n 
B 2 1150 GLU 1150 1150 ?   ?   ?   C . n 
B 2 1151 GLU 1151 1151 ?   ?   ?   C . n 
B 2 1152 LEU 1152 1152 ?   ?   ?   C . n 
B 2 1153 ASP 1153 1153 ?   ?   ?   C . n 
B 2 1154 LYS 1154 1154 ?   ?   ?   C . n 
B 2 1155 TYR 1155 1155 ?   ?   ?   C . n 
B 2 1156 PHE 1156 1156 ?   ?   ?   C . n 
B 2 1157 LYS 1157 1157 ?   ?   ?   C . n 
B 2 1158 ASN 1158 1158 ?   ?   ?   C . n 
B 2 1159 HIS 1159 1159 ?   ?   ?   C . n 
B 2 1160 THR 1160 1160 ?   ?   ?   C . n 
B 2 1161 SER 1161 1161 ?   ?   ?   C . n 
B 2 1162 PRO 1162 1162 ?   ?   ?   C . n 
B 2 1163 ASP 1163 1163 ?   ?   ?   C . n 
B 2 1164 VAL 1164 1164 ?   ?   ?   C . n 
B 2 1165 ASP 1165 1165 ?   ?   ?   C . n 
B 2 1166 LEU 1166 1166 ?   ?   ?   C . n 
B 2 1167 GLY 1167 1167 ?   ?   ?   C . n 
B 2 1168 ASP 1168 1168 ?   ?   ?   C . n 
B 2 1169 ILE 1169 1169 ?   ?   ?   C . n 
B 2 1170 SER 1170 1170 ?   ?   ?   C . n 
B 2 1171 GLY 1171 1171 ?   ?   ?   C . n 
B 2 1172 ILE 1172 1172 ?   ?   ?   C . n 
B 2 1173 ASN 1173 1173 ?   ?   ?   C . n 
B 2 1174 ALA 1174 1174 ?   ?   ?   C . n 
B 2 1175 SER 1175 1175 ?   ?   ?   C . n 
B 2 1176 VAL 1176 1176 ?   ?   ?   C . n 
B 2 1177 VAL 1177 1177 ?   ?   ?   C . n 
B 2 1178 ASN 1178 1178 ?   ?   ?   C . n 
B 2 1179 ILE 1179 1179 ?   ?   ?   C . n 
B 2 1180 GLN 1180 1180 ?   ?   ?   C . n 
B 2 1181 LYS 1181 1181 ?   ?   ?   C . n 
B 2 1182 GLU 1182 1182 ?   ?   ?   C . n 
B 2 1183 ILE 1183 1183 ?   ?   ?   C . n 
B 2 1184 ASP 1184 1184 ?   ?   ?   C . n 
B 2 1185 ARG 1185 1185 ?   ?   ?   C . n 
B 2 1186 LEU 1186 1186 ?   ?   ?   C . n 
B 2 1187 ASN 1187 1187 ?   ?   ?   C . n 
B 2 1188 GLU 1188 1188 ?   ?   ?   C . n 
B 2 1189 VAL 1189 1189 ?   ?   ?   C . n 
B 2 1190 ALA 1190 1190 ?   ?   ?   C . n 
B 2 1191 LYS 1191 1191 ?   ?   ?   C . n 
B 2 1192 ASN 1192 1192 ?   ?   ?   C . n 
B 2 1193 LEU 1193 1193 ?   ?   ?   C . n 
B 2 1194 ASN 1194 1194 ?   ?   ?   C . n 
B 2 1195 GLU 1195 1195 ?   ?   ?   C . n 
B 2 1196 SER 1196 1196 ?   ?   ?   C . n 
B 2 1197 LEU 1197 1197 ?   ?   ?   C . n 
B 2 1198 ILE 1198 1198 ?   ?   ?   C . n 
B 2 1199 ASP 1199 1199 ?   ?   ?   C . n 
B 2 1200 LEU 1200 1200 ?   ?   ?   C . n 
B 2 1201 GLN 1201 1201 ?   ?   ?   C . n 
B 2 1202 GLU 1202 1202 ?   ?   ?   C . n 
B 2 1203 LEU 1203 1203 ?   ?   ?   C . n 
B 2 1204 GLY 1204 1204 ?   ?   ?   C . n 
B 2 1205 LYS 1205 1205 ?   ?   ?   C . n 
B 2 1206 TYR 1206 1206 ?   ?   ?   C . n 
B 2 1207 GLU 1207 1207 ?   ?   ?   C . n 
B 2 1208 GLN 1208 1208 ?   ?   ?   C . n 
B 2 1209 GLY 1209 1209 ?   ?   ?   C . n 
B 2 1210 SER 1210 1210 ?   ?   ?   C . n 
B 2 1211 GLY 1211 1211 ?   ?   ?   C . n 
B 2 1212 TYR 1212 1212 ?   ?   ?   C . n 
B 2 1213 ILE 1213 1213 ?   ?   ?   C . n 
B 2 1214 PRO 1214 1214 ?   ?   ?   C . n 
B 2 1215 GLU 1215 1215 ?   ?   ?   C . n 
B 2 1216 ALA 1216 1216 ?   ?   ?   C . n 
B 2 1217 PRO 1217 1217 ?   ?   ?   C . n 
B 2 1218 ARG 1218 1218 ?   ?   ?   C . n 
B 2 1219 ASP 1219 1219 ?   ?   ?   C . n 
B 2 1220 GLY 1220 1220 ?   ?   ?   C . n 
B 2 1221 GLN 1221 1221 ?   ?   ?   C . n 
B 2 1222 ALA 1222 1222 ?   ?   ?   C . n 
B 2 1223 TYR 1223 1223 ?   ?   ?   C . n 
B 2 1224 VAL 1224 1224 ?   ?   ?   C . n 
B 2 1225 ARG 1225 1225 ?   ?   ?   C . n 
B 2 1226 LYS 1226 1226 ?   ?   ?   C . n 
B 2 1227 ASP 1227 1227 ?   ?   ?   C . n 
B 2 1228 GLY 1228 1228 ?   ?   ?   C . n 
B 2 1229 GLU 1229 1229 ?   ?   ?   C . n 
B 2 1230 TRP 1230 1230 ?   ?   ?   C . n 
B 2 1231 VAL 1231 1231 ?   ?   ?   C . n 
B 2 1232 PHE 1232 1232 ?   ?   ?   C . n 
B 2 1233 LEU 1233 1233 ?   ?   ?   C . n 
B 2 1234 SER 1234 1234 ?   ?   ?   C . n 
B 2 1235 THR 1235 1235 ?   ?   ?   C . n 
B 2 1236 PHE 1236 1236 ?   ?   ?   C . n 
B 2 1237 LEU 1237 1237 ?   ?   ?   C . n 
B 2 1238 SER 1238 1238 ?   ?   ?   C . n 
B 2 1239 GLY 1239 1239 ?   ?   ?   C . n 
B 2 1240 LEU 1240 1240 ?   ?   ?   C . n 
B 2 1241 GLU 1241 1241 ?   ?   ?   C . n 
B 2 1242 VAL 1242 1242 ?   ?   ?   C . n 
B 2 1243 LEU 1243 1243 ?   ?   ?   C . n 
B 2 1244 PHE 1244 1244 ?   ?   ?   C . n 
B 2 1245 GLN 1245 1245 ?   ?   ?   C . n 
B 2 1246 GLY 1246 1246 ?   ?   ?   C . n 
B 2 1247 PRO 1247 1247 ?   ?   ?   C . n 
B 2 1248 GLY 1248 1248 ?   ?   ?   C . n 
B 2 1249 GLY 1249 1249 ?   ?   ?   C . n 
B 2 1250 TRP 1250 1250 ?   ?   ?   C . n 
B 2 1251 SER 1251 1251 ?   ?   ?   C . n 
B 2 1252 HIS 1252 1252 ?   ?   ?   C . n 
B 2 1253 PRO 1253 1253 ?   ?   ?   C . n 
B 2 1254 GLN 1254 1254 ?   ?   ?   C . n 
B 2 1255 PHE 1255 1255 ?   ?   ?   C . n 
B 2 1256 GLU 1256 1256 ?   ?   ?   C . n 
B 2 1257 LYS 1257 1257 ?   ?   ?   C . n 
B 2 1258 GLY 1258 1258 ?   ?   ?   C . n 
B 2 1259 GLY 1259 1259 ?   ?   ?   C . n 
B 2 1260 GLY 1260 1260 ?   ?   ?   C . n 
B 2 1261 SER 1261 1261 ?   ?   ?   C . n 
B 2 1262 GLY 1262 1262 ?   ?   ?   C . n 
B 2 1263 GLY 1263 1263 ?   ?   ?   C . n 
B 2 1264 GLY 1264 1264 ?   ?   ?   C . n 
B 2 1265 SER 1265 1265 ?   ?   ?   C . n 
B 2 1266 GLY 1266 1266 ?   ?   ?   C . n 
B 2 1267 GLY 1267 1267 ?   ?   ?   C . n 
B 2 1268 SER 1268 1268 ?   ?   ?   C . n 
B 2 1269 ALA 1269 1269 ?   ?   ?   C . n 
B 2 1270 TRP 1270 1270 ?   ?   ?   C . n 
B 2 1271 SER 1271 1271 ?   ?   ?   C . n 
B 2 1272 HIS 1272 1272 ?   ?   ?   C . n 
B 2 1273 PRO 1273 1273 ?   ?   ?   C . n 
B 2 1274 GLN 1274 1274 ?   ?   ?   C . n 
B 2 1275 PHE 1275 1275 ?   ?   ?   C . n 
B 2 1276 GLU 1276 1276 ?   ?   ?   C . n 
B 2 1277 LYS 1277 1277 ?   ?   ?   C . n 
B 2 1278 GLY 1278 1278 ?   ?   ?   C . n 
B 2 1279 GLY 1279 1279 ?   ?   ?   C . n 
B 2 1280 SER 1280 1280 ?   ?   ?   C . n 
B 2 1281 HIS 1281 1281 ?   ?   ?   C . n 
B 2 1282 HIS 1282 1282 ?   ?   ?   C . n 
B 2 1283 HIS 1283 1283 ?   ?   ?   C . n 
B 2 1284 HIS 1284 1284 ?   ?   ?   C . n 
B 2 1285 HIS 1285 1285 ?   ?   ?   C . n 
B 2 1286 HIS 1286 1286 ?   ?   ?   C . n 
B 2 1287 HIS 1287 1287 ?   ?   ?   C . n 
B 2 1288 HIS 1288 1288 ?   ?   ?   C . n 
C 2 1    MET 1    1    ?   ?   ?   A . n 
C 2 2    PHE 2    2    ?   ?   ?   A . n 
C 2 3    VAL 3    3    ?   ?   ?   A . n 
C 2 4    PHE 4    4    ?   ?   ?   A . n 
C 2 5    LEU 5    5    ?   ?   ?   A . n 
C 2 6    VAL 6    6    ?   ?   ?   A . n 
C 2 7    LEU 7    7    ?   ?   ?   A . n 
C 2 8    LEU 8    8    ?   ?   ?   A . n 
C 2 9    PRO 9    9    ?   ?   ?   A . n 
C 2 10   LEU 10   10   ?   ?   ?   A . n 
C 2 11   VAL 11   11   ?   ?   ?   A . n 
C 2 12   SER 12   12   ?   ?   ?   A . n 
C 2 13   SER 13   13   ?   ?   ?   A . n 
C 2 14   GLN 14   14   ?   ?   ?   A . n 
C 2 15   CYS 15   15   ?   ?   ?   A . n 
C 2 16   VAL 16   16   ?   ?   ?   A . n 
C 2 17   ASN 17   17   ?   ?   ?   A . n 
C 2 18   LEU 18   18   ?   ?   ?   A . n 
C 2 19   THR 19   19   ?   ?   ?   A . n 
C 2 20   THR 20   20   ?   ?   ?   A . n 
C 2 21   ARG 21   21   ?   ?   ?   A . n 
C 2 22   THR 22   22   ?   ?   ?   A . n 
C 2 23   GLN 23   23   ?   ?   ?   A . n 
C 2 24   LEU 24   24   ?   ?   ?   A . n 
C 2 25   PRO 25   25   ?   ?   ?   A . n 
C 2 26   PRO 26   26   ?   ?   ?   A . n 
C 2 27   ALA 27   27   ?   ?   ?   A . n 
C 2 28   TYR 28   28   ?   ?   ?   A . n 
C 2 29   THR 29   29   ?   ?   ?   A . n 
C 2 30   ASN 30   30   ?   ?   ?   A . n 
C 2 31   SER 31   31   ?   ?   ?   A . n 
C 2 32   PHE 32   32   ?   ?   ?   A . n 
C 2 33   THR 33   33   ?   ?   ?   A . n 
C 2 34   ARG 34   34   ?   ?   ?   A . n 
C 2 35   GLY 35   35   ?   ?   ?   A . n 
C 2 36   VAL 36   36   ?   ?   ?   A . n 
C 2 37   TYR 37   37   ?   ?   ?   A . n 
C 2 38   TYR 38   38   ?   ?   ?   A . n 
C 2 39   PRO 39   39   ?   ?   ?   A . n 
C 2 40   ASP 40   40   ?   ?   ?   A . n 
C 2 41   LYS 41   41   ?   ?   ?   A . n 
C 2 42   VAL 42   42   ?   ?   ?   A . n 
C 2 43   PHE 43   43   ?   ?   ?   A . n 
C 2 44   ARG 44   44   ?   ?   ?   A . n 
C 2 45   SER 45   45   ?   ?   ?   A . n 
C 2 46   SER 46   46   ?   ?   ?   A . n 
C 2 47   VAL 47   47   ?   ?   ?   A . n 
C 2 48   LEU 48   48   ?   ?   ?   A . n 
C 2 49   HIS 49   49   ?   ?   ?   A . n 
C 2 50   SER 50   50   ?   ?   ?   A . n 
C 2 51   THR 51   51   ?   ?   ?   A . n 
C 2 52   GLN 52   52   ?   ?   ?   A . n 
C 2 53   ASP 53   53   ?   ?   ?   A . n 
C 2 54   LEU 54   54   ?   ?   ?   A . n 
C 2 55   PHE 55   55   ?   ?   ?   A . n 
C 2 56   LEU 56   56   ?   ?   ?   A . n 
C 2 57   PRO 57   57   ?   ?   ?   A . n 
C 2 58   PHE 58   58   ?   ?   ?   A . n 
C 2 59   PHE 59   59   ?   ?   ?   A . n 
C 2 60   SER 60   60   ?   ?   ?   A . n 
C 2 61   ASN 61   61   ?   ?   ?   A . n 
C 2 62   VAL 62   62   ?   ?   ?   A . n 
C 2 63   THR 63   63   ?   ?   ?   A . n 
C 2 64   TRP 64   64   ?   ?   ?   A . n 
C 2 65   PHE 65   65   ?   ?   ?   A . n 
C 2 66   HIS 66   66   ?   ?   ?   A . n 
C 2 67   ALA 67   67   ?   ?   ?   A . n 
C 2 68   ILE 68   68   ?   ?   ?   A . n 
C 2 69   HIS 69   69   ?   ?   ?   A . n 
C 2 70   VAL 70   70   ?   ?   ?   A . n 
C 2 71   SER 71   71   ?   ?   ?   A . n 
C 2 72   GLY 72   72   ?   ?   ?   A . n 
C 2 73   THR 73   73   ?   ?   ?   A . n 
C 2 74   ASN 74   74   ?   ?   ?   A . n 
C 2 75   GLY 75   75   ?   ?   ?   A . n 
C 2 76   THR 76   76   ?   ?   ?   A . n 
C 2 77   LYS 77   77   ?   ?   ?   A . n 
C 2 78   ARG 78   78   ?   ?   ?   A . n 
C 2 79   PHE 79   79   ?   ?   ?   A . n 
C 2 80   ASP 80   80   ?   ?   ?   A . n 
C 2 81   ASN 81   81   ?   ?   ?   A . n 
C 2 82   PRO 82   82   ?   ?   ?   A . n 
C 2 83   VAL 83   83   ?   ?   ?   A . n 
C 2 84   LEU 84   84   ?   ?   ?   A . n 
C 2 85   PRO 85   85   ?   ?   ?   A . n 
C 2 86   PHE 86   86   ?   ?   ?   A . n 
C 2 87   ASN 87   87   ?   ?   ?   A . n 
C 2 88   ASP 88   88   ?   ?   ?   A . n 
C 2 89   GLY 89   89   ?   ?   ?   A . n 
C 2 90   VAL 90   90   ?   ?   ?   A . n 
C 2 91   TYR 91   91   ?   ?   ?   A . n 
C 2 92   PHE 92   92   ?   ?   ?   A . n 
C 2 93   ALA 93   93   ?   ?   ?   A . n 
C 2 94   SER 94   94   ?   ?   ?   A . n 
C 2 95   THR 95   95   ?   ?   ?   A . n 
C 2 96   GLU 96   96   ?   ?   ?   A . n 
C 2 97   LYS 97   97   ?   ?   ?   A . n 
C 2 98   SER 98   98   ?   ?   ?   A . n 
C 2 99   ASN 99   99   ?   ?   ?   A . n 
C 2 100  ILE 100  100  ?   ?   ?   A . n 
C 2 101  ILE 101  101  ?   ?   ?   A . n 
C 2 102  ARG 102  102  ?   ?   ?   A . n 
C 2 103  GLY 103  103  ?   ?   ?   A . n 
C 2 104  TRP 104  104  ?   ?   ?   A . n 
C 2 105  ILE 105  105  ?   ?   ?   A . n 
C 2 106  PHE 106  106  ?   ?   ?   A . n 
C 2 107  GLY 107  107  ?   ?   ?   A . n 
C 2 108  THR 108  108  ?   ?   ?   A . n 
C 2 109  THR 109  109  ?   ?   ?   A . n 
C 2 110  LEU 110  110  ?   ?   ?   A . n 
C 2 111  ASP 111  111  ?   ?   ?   A . n 
C 2 112  SER 112  112  ?   ?   ?   A . n 
C 2 113  LYS 113  113  ?   ?   ?   A . n 
C 2 114  THR 114  114  ?   ?   ?   A . n 
C 2 115  GLN 115  115  ?   ?   ?   A . n 
C 2 116  SER 116  116  ?   ?   ?   A . n 
C 2 117  LEU 117  117  ?   ?   ?   A . n 
C 2 118  LEU 118  118  ?   ?   ?   A . n 
C 2 119  ILE 119  119  ?   ?   ?   A . n 
C 2 120  VAL 120  120  ?   ?   ?   A . n 
C 2 121  ASN 121  121  ?   ?   ?   A . n 
C 2 122  ASN 122  122  ?   ?   ?   A . n 
C 2 123  ALA 123  123  ?   ?   ?   A . n 
C 2 124  THR 124  124  ?   ?   ?   A . n 
C 2 125  ASN 125  125  ?   ?   ?   A . n 
C 2 126  VAL 126  126  ?   ?   ?   A . n 
C 2 127  VAL 127  127  ?   ?   ?   A . n 
C 2 128  ILE 128  128  ?   ?   ?   A . n 
C 2 129  LYS 129  129  ?   ?   ?   A . n 
C 2 130  VAL 130  130  ?   ?   ?   A . n 
C 2 131  CYS 131  131  ?   ?   ?   A . n 
C 2 132  GLU 132  132  ?   ?   ?   A . n 
C 2 133  PHE 133  133  ?   ?   ?   A . n 
C 2 134  GLN 134  134  ?   ?   ?   A . n 
C 2 135  PHE 135  135  ?   ?   ?   A . n 
C 2 136  CYS 136  136  ?   ?   ?   A . n 
C 2 137  ASN 137  137  ?   ?   ?   A . n 
C 2 138  ASP 138  138  ?   ?   ?   A . n 
C 2 139  PRO 139  139  ?   ?   ?   A . n 
C 2 140  PHE 140  140  ?   ?   ?   A . n 
C 2 141  LEU 141  141  ?   ?   ?   A . n 
C 2 142  GLY 142  142  ?   ?   ?   A . n 
C 2 143  VAL 143  143  ?   ?   ?   A . n 
C 2 144  TYR 144  144  ?   ?   ?   A . n 
C 2 145  TYR 145  145  ?   ?   ?   A . n 
C 2 146  HIS 146  146  ?   ?   ?   A . n 
C 2 147  LYS 147  147  ?   ?   ?   A . n 
C 2 148  ASN 148  148  ?   ?   ?   A . n 
C 2 149  ASN 149  149  ?   ?   ?   A . n 
C 2 150  LYS 150  150  ?   ?   ?   A . n 
C 2 151  SER 151  151  ?   ?   ?   A . n 
C 2 152  TRP 152  152  ?   ?   ?   A . n 
C 2 153  MET 153  153  ?   ?   ?   A . n 
C 2 154  GLU 154  154  ?   ?   ?   A . n 
C 2 155  SER 155  155  ?   ?   ?   A . n 
C 2 156  GLU 156  156  ?   ?   ?   A . n 
C 2 157  PHE 157  157  ?   ?   ?   A . n 
C 2 158  ARG 158  158  ?   ?   ?   A . n 
C 2 159  VAL 159  159  ?   ?   ?   A . n 
C 2 160  TYR 160  160  ?   ?   ?   A . n 
C 2 161  SER 161  161  ?   ?   ?   A . n 
C 2 162  SER 162  162  ?   ?   ?   A . n 
C 2 163  ALA 163  163  ?   ?   ?   A . n 
C 2 164  ASN 164  164  ?   ?   ?   A . n 
C 2 165  ASN 165  165  ?   ?   ?   A . n 
C 2 166  CYS 166  166  ?   ?   ?   A . n 
C 2 167  THR 167  167  ?   ?   ?   A . n 
C 2 168  PHE 168  168  ?   ?   ?   A . n 
C 2 169  GLU 169  169  ?   ?   ?   A . n 
C 2 170  TYR 170  170  ?   ?   ?   A . n 
C 2 171  VAL 171  171  ?   ?   ?   A . n 
C 2 172  SER 172  172  ?   ?   ?   A . n 
C 2 173  GLN 173  173  ?   ?   ?   A . n 
C 2 174  PRO 174  174  ?   ?   ?   A . n 
C 2 175  PHE 175  175  ?   ?   ?   A . n 
C 2 176  LEU 176  176  ?   ?   ?   A . n 
C 2 177  MET 177  177  ?   ?   ?   A . n 
C 2 178  ASP 178  178  ?   ?   ?   A . n 
C 2 179  LEU 179  179  ?   ?   ?   A . n 
C 2 180  GLU 180  180  ?   ?   ?   A . n 
C 2 181  GLY 181  181  ?   ?   ?   A . n 
C 2 182  LYS 182  182  ?   ?   ?   A . n 
C 2 183  GLN 183  183  ?   ?   ?   A . n 
C 2 184  GLY 184  184  ?   ?   ?   A . n 
C 2 185  ASN 185  185  ?   ?   ?   A . n 
C 2 186  PHE 186  186  ?   ?   ?   A . n 
C 2 187  LYS 187  187  ?   ?   ?   A . n 
C 2 188  ASN 188  188  ?   ?   ?   A . n 
C 2 189  LEU 189  189  ?   ?   ?   A . n 
C 2 190  ARG 190  190  ?   ?   ?   A . n 
C 2 191  GLU 191  191  ?   ?   ?   A . n 
C 2 192  PHE 192  192  ?   ?   ?   A . n 
C 2 193  VAL 193  193  ?   ?   ?   A . n 
C 2 194  PHE 194  194  ?   ?   ?   A . n 
C 2 195  LYS 195  195  ?   ?   ?   A . n 
C 2 196  ASN 196  196  ?   ?   ?   A . n 
C 2 197  ILE 197  197  ?   ?   ?   A . n 
C 2 198  ASP 198  198  ?   ?   ?   A . n 
C 2 199  GLY 199  199  ?   ?   ?   A . n 
C 2 200  TYR 200  200  ?   ?   ?   A . n 
C 2 201  PHE 201  201  ?   ?   ?   A . n 
C 2 202  LYS 202  202  ?   ?   ?   A . n 
C 2 203  ILE 203  203  ?   ?   ?   A . n 
C 2 204  TYR 204  204  ?   ?   ?   A . n 
C 2 205  SER 205  205  ?   ?   ?   A . n 
C 2 206  LYS 206  206  ?   ?   ?   A . n 
C 2 207  HIS 207  207  ?   ?   ?   A . n 
C 2 208  THR 208  208  ?   ?   ?   A . n 
C 2 209  PRO 209  209  ?   ?   ?   A . n 
C 2 210  ILE 210  210  ?   ?   ?   A . n 
C 2 211  ASN 211  211  ?   ?   ?   A . n 
C 2 212  LEU 212  212  ?   ?   ?   A . n 
C 2 213  VAL 213  213  ?   ?   ?   A . n 
C 2 214  ARG 214  214  ?   ?   ?   A . n 
C 2 215  ASP 215  215  ?   ?   ?   A . n 
C 2 216  LEU 216  216  ?   ?   ?   A . n 
C 2 217  PRO 217  217  ?   ?   ?   A . n 
C 2 218  GLN 218  218  ?   ?   ?   A . n 
C 2 219  GLY 219  219  ?   ?   ?   A . n 
C 2 220  PHE 220  220  ?   ?   ?   A . n 
C 2 221  SER 221  221  ?   ?   ?   A . n 
C 2 222  ALA 222  222  ?   ?   ?   A . n 
C 2 223  LEU 223  223  ?   ?   ?   A . n 
C 2 224  GLU 224  224  ?   ?   ?   A . n 
C 2 225  PRO 225  225  ?   ?   ?   A . n 
C 2 226  LEU 226  226  ?   ?   ?   A . n 
C 2 227  VAL 227  227  ?   ?   ?   A . n 
C 2 228  ASP 228  228  ?   ?   ?   A . n 
C 2 229  LEU 229  229  ?   ?   ?   A . n 
C 2 230  PRO 230  230  ?   ?   ?   A . n 
C 2 231  ILE 231  231  ?   ?   ?   A . n 
C 2 232  GLY 232  232  ?   ?   ?   A . n 
C 2 233  ILE 233  233  ?   ?   ?   A . n 
C 2 234  ASN 234  234  ?   ?   ?   A . n 
C 2 235  ILE 235  235  ?   ?   ?   A . n 
C 2 236  THR 236  236  ?   ?   ?   A . n 
C 2 237  ARG 237  237  ?   ?   ?   A . n 
C 2 238  PHE 238  238  ?   ?   ?   A . n 
C 2 239  GLN 239  239  ?   ?   ?   A . n 
C 2 240  THR 240  240  ?   ?   ?   A . n 
C 2 241  LEU 241  241  ?   ?   ?   A . n 
C 2 242  LEU 242  242  ?   ?   ?   A . n 
C 2 243  ALA 243  243  ?   ?   ?   A . n 
C 2 244  LEU 244  244  ?   ?   ?   A . n 
C 2 245  HIS 245  245  ?   ?   ?   A . n 
C 2 246  ARG 246  246  ?   ?   ?   A . n 
C 2 247  SER 247  247  ?   ?   ?   A . n 
C 2 248  TYR 248  248  ?   ?   ?   A . n 
C 2 249  LEU 249  249  ?   ?   ?   A . n 
C 2 250  THR 250  250  ?   ?   ?   A . n 
C 2 251  PRO 251  251  ?   ?   ?   A . n 
C 2 252  GLY 252  252  ?   ?   ?   A . n 
C 2 253  ASP 253  253  ?   ?   ?   A . n 
C 2 254  SER 254  254  ?   ?   ?   A . n 
C 2 255  SER 255  255  ?   ?   ?   A . n 
C 2 256  SER 256  256  ?   ?   ?   A . n 
C 2 257  GLY 257  257  ?   ?   ?   A . n 
C 2 258  TRP 258  258  ?   ?   ?   A . n 
C 2 259  THR 259  259  ?   ?   ?   A . n 
C 2 260  ALA 260  260  ?   ?   ?   A . n 
C 2 261  GLY 261  261  ?   ?   ?   A . n 
C 2 262  ALA 262  262  ?   ?   ?   A . n 
C 2 263  ALA 263  263  ?   ?   ?   A . n 
C 2 264  ALA 264  264  ?   ?   ?   A . n 
C 2 265  TYR 265  265  ?   ?   ?   A . n 
C 2 266  TYR 266  266  ?   ?   ?   A . n 
C 2 267  VAL 267  267  ?   ?   ?   A . n 
C 2 268  GLY 268  268  ?   ?   ?   A . n 
C 2 269  TYR 269  269  ?   ?   ?   A . n 
C 2 270  LEU 270  270  ?   ?   ?   A . n 
C 2 271  GLN 271  271  ?   ?   ?   A . n 
C 2 272  PRO 272  272  ?   ?   ?   A . n 
C 2 273  ARG 273  273  ?   ?   ?   A . n 
C 2 274  THR 274  274  ?   ?   ?   A . n 
C 2 275  PHE 275  275  ?   ?   ?   A . n 
C 2 276  LEU 276  276  ?   ?   ?   A . n 
C 2 277  LEU 277  277  ?   ?   ?   A . n 
C 2 278  LYS 278  278  ?   ?   ?   A . n 
C 2 279  TYR 279  279  ?   ?   ?   A . n 
C 2 280  ASN 280  280  ?   ?   ?   A . n 
C 2 281  GLU 281  281  ?   ?   ?   A . n 
C 2 282  ASN 282  282  ?   ?   ?   A . n 
C 2 283  GLY 283  283  ?   ?   ?   A . n 
C 2 284  THR 284  284  ?   ?   ?   A . n 
C 2 285  ILE 285  285  ?   ?   ?   A . n 
C 2 286  THR 286  286  ?   ?   ?   A . n 
C 2 287  ASP 287  287  ?   ?   ?   A . n 
C 2 288  ALA 288  288  ?   ?   ?   A . n 
C 2 289  VAL 289  289  ?   ?   ?   A . n 
C 2 290  ASP 290  290  ?   ?   ?   A . n 
C 2 291  CYS 291  291  ?   ?   ?   A . n 
C 2 292  ALA 292  292  ?   ?   ?   A . n 
C 2 293  LEU 293  293  ?   ?   ?   A . n 
C 2 294  ASP 294  294  ?   ?   ?   A . n 
C 2 295  PRO 295  295  ?   ?   ?   A . n 
C 2 296  LEU 296  296  ?   ?   ?   A . n 
C 2 297  SER 297  297  ?   ?   ?   A . n 
C 2 298  GLU 298  298  ?   ?   ?   A . n 
C 2 299  THR 299  299  ?   ?   ?   A . n 
C 2 300  LYS 300  300  ?   ?   ?   A . n 
C 2 301  CYS 301  301  ?   ?   ?   A . n 
C 2 302  THR 302  302  ?   ?   ?   A . n 
C 2 303  LEU 303  303  ?   ?   ?   A . n 
C 2 304  LYS 304  304  ?   ?   ?   A . n 
C 2 305  SER 305  305  ?   ?   ?   A . n 
C 2 306  PHE 306  306  ?   ?   ?   A . n 
C 2 307  THR 307  307  ?   ?   ?   A . n 
C 2 308  VAL 308  308  ?   ?   ?   A . n 
C 2 309  GLU 309  309  ?   ?   ?   A . n 
C 2 310  LYS 310  310  ?   ?   ?   A . n 
C 2 311  GLY 311  311  ?   ?   ?   A . n 
C 2 312  ILE 312  312  ?   ?   ?   A . n 
C 2 313  TYR 313  313  ?   ?   ?   A . n 
C 2 314  GLN 314  314  ?   ?   ?   A . n 
C 2 315  THR 315  315  ?   ?   ?   A . n 
C 2 316  SER 316  316  ?   ?   ?   A . n 
C 2 317  ASN 317  317  ?   ?   ?   A . n 
C 2 318  PHE 318  318  ?   ?   ?   A . n 
C 2 319  ARG 319  319  ?   ?   ?   A . n 
C 2 320  VAL 320  320  320 VAL VAL A . n 
C 2 321  GLN 321  321  321 GLN GLN A . n 
C 2 322  PRO 322  322  322 PRO PRO A . n 
C 2 323  THR 323  323  323 THR THR A . n 
C 2 324  GLU 324  324  324 GLU GLU A . n 
C 2 325  SER 325  325  325 SER SER A . n 
C 2 326  ILE 326  326  326 ILE ILE A . n 
C 2 327  VAL 327  327  327 VAL VAL A . n 
C 2 328  ARG 328  328  328 ARG ARG A . n 
C 2 329  PHE 329  329  329 PHE PHE A . n 
C 2 330  PRO 330  330  330 PRO PRO A . n 
C 2 331  ASN 331  331  331 ASN ASN A . n 
C 2 332  ILE 332  332  332 ILE ILE A . n 
C 2 333  THR 333  333  333 THR THR A . n 
C 2 334  ASN 334  334  334 ASN ASN A . n 
C 2 335  LEU 335  335  335 LEU LEU A . n 
C 2 336  CYS 336  336  336 CYS CYS A . n 
C 2 337  PRO 337  337  337 PRO PRO A . n 
C 2 338  PHE 338  338  338 PHE PHE A . n 
C 2 339  GLY 339  339  339 GLY GLY A . n 
C 2 340  GLU 340  340  340 GLU GLU A . n 
C 2 341  VAL 341  341  341 VAL VAL A . n 
C 2 342  PHE 342  342  342 PHE PHE A . n 
C 2 343  ASN 343  343  343 ASN ASN A . n 
C 2 344  ALA 344  344  344 ALA ALA A . n 
C 2 345  THR 345  345  345 THR THR A . n 
C 2 346  ARG 346  346  346 ARG ARG A . n 
C 2 347  PHE 347  347  347 PHE PHE A . n 
C 2 348  ALA 348  348  348 ALA ALA A . n 
C 2 349  SER 349  349  349 SER SER A . n 
C 2 350  VAL 350  350  350 VAL VAL A . n 
C 2 351  TYR 351  351  351 TYR TYR A . n 
C 2 352  ALA 352  352  352 ALA ALA A . n 
C 2 353  TRP 353  353  353 TRP TRP A . n 
C 2 354  ASN 354  354  354 ASN ASN A . n 
C 2 355  ARG 355  355  355 ARG ARG A . n 
C 2 356  LYS 356  356  356 LYS LYS A . n 
C 2 357  ARG 357  357  357 ARG ARG A . n 
C 2 358  ILE 358  358  358 ILE ILE A . n 
C 2 359  SER 359  359  359 SER SER A . n 
C 2 360  ASN 360  360  360 ASN ASN A . n 
C 2 361  CYS 361  361  361 CYS CYS A . n 
C 2 362  VAL 362  362  362 VAL VAL A . n 
C 2 363  ALA 363  363  363 ALA ALA A . n 
C 2 364  ASP 364  364  364 ASP ASP A . n 
C 2 365  TYR 365  365  365 TYR TYR A . n 
C 2 366  SER 366  366  366 SER SER A . n 
C 2 367  VAL 367  367  367 VAL VAL A . n 
C 2 368  LEU 368  368  368 LEU LEU A . n 
C 2 369  TYR 369  369  369 TYR TYR A . n 
C 2 370  ASN 370  370  370 ASN ASN A . n 
C 2 371  SER 371  371  371 SER SER A . n 
C 2 372  ALA 372  372  372 ALA ALA A . n 
C 2 373  SER 373  373  373 SER SER A . n 
C 2 374  PHE 374  374  374 PHE PHE A . n 
C 2 375  SER 375  375  375 SER SER A . n 
C 2 376  THR 376  376  376 THR THR A . n 
C 2 377  PHE 377  377  377 PHE PHE A . n 
C 2 378  LYS 378  378  378 LYS LYS A . n 
C 2 379  CYS 379  379  379 CYS CYS A . n 
C 2 380  TYR 380  380  380 TYR TYR A . n 
C 2 381  GLY 381  381  381 GLY GLY A . n 
C 2 382  VAL 382  382  382 VAL VAL A . n 
C 2 383  SER 383  383  383 SER SER A . n 
C 2 384  PRO 384  384  384 PRO PRO A . n 
C 2 385  THR 385  385  385 THR THR A . n 
C 2 386  LYS 386  386  386 LYS LYS A . n 
C 2 387  LEU 387  387  387 LEU LEU A . n 
C 2 388  ASN 388  388  388 ASN ASN A . n 
C 2 389  ASP 389  389  389 ASP ASP A . n 
C 2 390  LEU 390  390  390 LEU LEU A . n 
C 2 391  CYS 391  391  391 CYS CYS A . n 
C 2 392  PHE 392  392  392 PHE PHE A . n 
C 2 393  THR 393  393  393 THR THR A . n 
C 2 394  ASN 394  394  394 ASN ASN A . n 
C 2 395  VAL 395  395  395 VAL VAL A . n 
C 2 396  TYR 396  396  396 TYR TYR A . n 
C 2 397  ALA 397  397  397 ALA ALA A . n 
C 2 398  ASP 398  398  398 ASP ASP A . n 
C 2 399  SER 399  399  399 SER SER A . n 
C 2 400  PHE 400  400  400 PHE PHE A . n 
C 2 401  VAL 401  401  401 VAL VAL A . n 
C 2 402  ILE 402  402  402 ILE ILE A . n 
C 2 403  ARG 403  403  403 ARG ARG A . n 
C 2 404  GLY 404  404  404 GLY GLY A . n 
C 2 405  ASP 405  405  405 ASP ASP A . n 
C 2 406  GLU 406  406  406 GLU GLU A . n 
C 2 407  VAL 407  407  407 VAL VAL A . n 
C 2 408  ARG 408  408  408 ARG ARG A . n 
C 2 409  GLN 409  409  409 GLN GLN A . n 
C 2 410  ILE 410  410  410 ILE ILE A . n 
C 2 411  ALA 411  411  411 ALA ALA A . n 
C 2 412  PRO 412  412  412 PRO PRO A . n 
C 2 413  GLY 413  413  413 GLY GLY A . n 
C 2 414  GLN 414  414  414 GLN GLN A . n 
C 2 415  THR 415  415  415 THR THR A . n 
C 2 416  GLY 416  416  416 GLY GLY A . n 
C 2 417  LYS 417  417  417 LYS LYS A . n 
C 2 418  ILE 418  418  418 ILE ILE A . n 
C 2 419  ALA 419  419  419 ALA ALA A . n 
C 2 420  ASP 420  420  420 ASP ASP A . n 
C 2 421  TYR 421  421  421 TYR TYR A . n 
C 2 422  ASN 422  422  422 ASN ASN A . n 
C 2 423  TYR 423  423  423 TYR TYR A . n 
C 2 424  LYS 424  424  424 LYS LYS A . n 
C 2 425  LEU 425  425  425 LEU LEU A . n 
C 2 426  PRO 426  426  426 PRO PRO A . n 
C 2 427  ASP 427  427  427 ASP ASP A . n 
C 2 428  ASP 428  428  428 ASP ASP A . n 
C 2 429  PHE 429  429  429 PHE PHE A . n 
C 2 430  THR 430  430  430 THR THR A . n 
C 2 431  GLY 431  431  431 GLY GLY A . n 
C 2 432  CYS 432  432  432 CYS CYS A . n 
C 2 433  VAL 433  433  433 VAL VAL A . n 
C 2 434  ILE 434  434  434 ILE ILE A . n 
C 2 435  ALA 435  435  435 ALA ALA A . n 
C 2 436  TRP 436  436  436 TRP TRP A . n 
C 2 437  ASN 437  437  437 ASN ASN A . n 
C 2 438  SER 438  438  438 SER SER A . n 
C 2 439  ASN 439  439  439 ASN ASN A . n 
C 2 440  ASN 440  440  440 ASN ASN A . n 
C 2 441  LEU 441  441  441 LEU LEU A . n 
C 2 442  ASP 442  442  442 ASP ASP A . n 
C 2 443  SER 443  443  443 SER SER A . n 
C 2 444  LYS 444  444  444 LYS LYS A . n 
C 2 445  VAL 445  445  445 VAL VAL A . n 
C 2 446  GLY 446  446  446 GLY GLY A . n 
C 2 447  GLY 447  447  447 GLY GLY A . n 
C 2 448  ASN 448  448  448 ASN ASN A . n 
C 2 449  TYR 449  449  449 TYR TYR A . n 
C 2 450  ASN 450  450  450 ASN ASN A . n 
C 2 451  TYR 451  451  451 TYR TYR A . n 
C 2 452  LEU 452  452  452 LEU LEU A . n 
C 2 453  TYR 453  453  453 TYR TYR A . n 
C 2 454  ARG 454  454  454 ARG ARG A . n 
C 2 455  LEU 455  455  455 LEU LEU A . n 
C 2 456  PHE 456  456  456 PHE PHE A . n 
C 2 457  ARG 457  457  457 ARG ARG A . n 
C 2 458  LYS 458  458  458 LYS LYS A . n 
C 2 459  SER 459  459  459 SER SER A . n 
C 2 460  ASN 460  460  460 ASN ASN A . n 
C 2 461  LEU 461  461  461 LEU LEU A . n 
C 2 462  LYS 462  462  462 LYS LYS A . n 
C 2 463  PRO 463  463  463 PRO PRO A . n 
C 2 464  PHE 464  464  464 PHE PHE A . n 
C 2 465  GLU 465  465  465 GLU GLU A . n 
C 2 466  ARG 466  466  466 ARG ARG A . n 
C 2 467  ASP 467  467  467 ASP ASP A . n 
C 2 468  ILE 468  468  468 ILE ILE A . n 
C 2 469  SER 469  469  469 SER SER A . n 
C 2 470  THR 470  470  470 THR THR A . n 
C 2 471  GLU 471  471  471 GLU GLU A . n 
C 2 472  ILE 472  472  472 ILE ILE A . n 
C 2 473  TYR 473  473  473 TYR TYR A . n 
C 2 474  GLN 474  474  474 GLN GLN A . n 
C 2 475  ALA 475  475  475 ALA ALA A . n 
C 2 476  GLY 476  476  476 GLY GLY A . n 
C 2 477  SER 477  477  477 SER SER A . n 
C 2 478  THR 478  478  478 THR THR A . n 
C 2 479  PRO 479  479  479 PRO PRO A . n 
C 2 480  CYS 480  480  480 CYS CYS A . n 
C 2 481  ASN 481  481  481 ASN ASN A . n 
C 2 482  GLY 482  482  482 GLY GLY A . n 
C 2 483  VAL 483  483  483 VAL VAL A . n 
C 2 484  GLU 484  484  484 GLU GLU A . n 
C 2 485  GLY 485  485  485 GLY GLY A . n 
C 2 486  PHE 486  486  486 PHE PHE A . n 
C 2 487  ASN 487  487  487 ASN ASN A . n 
C 2 488  CYS 488  488  488 CYS CYS A . n 
C 2 489  TYR 489  489  489 TYR TYR A . n 
C 2 490  PHE 490  490  490 PHE PHE A . n 
C 2 491  PRO 491  491  491 PRO PRO A . n 
C 2 492  LEU 492  492  492 LEU LEU A . n 
C 2 493  GLN 493  493  493 GLN GLN A . n 
C 2 494  SER 494  494  494 SER SER A . n 
C 2 495  TYR 495  495  495 TYR TYR A . n 
C 2 496  GLY 496  496  496 GLY GLY A . n 
C 2 497  PHE 497  497  497 PHE PHE A . n 
C 2 498  GLN 498  498  498 GLN GLN A . n 
C 2 499  PRO 499  499  499 PRO PRO A . n 
C 2 500  THR 500  500  500 THR THR A . n 
C 2 501  ASN 501  501  501 ASN ASN A . n 
C 2 502  GLY 502  502  502 GLY GLY A . n 
C 2 503  VAL 503  503  503 VAL VAL A . n 
C 2 504  GLY 504  504  504 GLY GLY A . n 
C 2 505  TYR 505  505  505 TYR TYR A . n 
C 2 506  GLN 506  506  506 GLN GLN A . n 
C 2 507  PRO 507  507  507 PRO PRO A . n 
C 2 508  TYR 508  508  508 TYR TYR A . n 
C 2 509  ARG 509  509  509 ARG ARG A . n 
C 2 510  VAL 510  510  510 VAL VAL A . n 
C 2 511  VAL 511  511  511 VAL VAL A . n 
C 2 512  VAL 512  512  512 VAL VAL A . n 
C 2 513  LEU 513  513  513 LEU LEU A . n 
C 2 514  SER 514  514  514 SER SER A . n 
C 2 515  PHE 515  515  515 PHE PHE A . n 
C 2 516  GLU 516  516  516 GLU GLU A . n 
C 2 517  LEU 517  517  517 LEU LEU A . n 
C 2 518  LEU 518  518  518 LEU LEU A . n 
C 2 519  HIS 519  519  519 HIS HIS A . n 
C 2 520  ALA 520  520  520 ALA ALA A . n 
C 2 521  PRO 521  521  521 PRO PRO A . n 
C 2 522  ALA 522  522  522 ALA ALA A . n 
C 2 523  THR 523  523  523 THR THR A . n 
C 2 524  VAL 524  524  524 VAL VAL A . n 
C 2 525  CYS 525  525  525 CYS CYS A . n 
C 2 526  GLY 526  526  526 GLY GLY A . n 
C 2 527  PRO 527  527  527 PRO PRO A . n 
C 2 528  LYS 528  528  528 LYS LYS A . n 
C 2 529  LYS 529  529  529 LYS LYS A . n 
C 2 530  SER 530  530  530 SER SER A . n 
C 2 531  THR 531  531  531 THR THR A . n 
C 2 532  ASN 532  532  532 ASN ASN A . n 
C 2 533  LEU 533  533  533 LEU LEU A . n 
C 2 534  VAL 534  534  534 VAL VAL A . n 
C 2 535  LYS 535  535  535 LYS LYS A . n 
C 2 536  ASN 536  536  536 ASN ASN A . n 
C 2 537  LYS 537  537  537 LYS LYS A . n 
C 2 538  CYS 538  538  538 CYS CYS A . n 
C 2 539  VAL 539  539  539 VAL VAL A . n 
C 2 540  ASN 540  540  540 ASN ASN A . n 
C 2 541  PHE 541  541  541 PHE PHE A . n 
C 2 542  ASN 542  542  542 ASN ASN A . n 
C 2 543  PHE 543  543  543 PHE PHE A . n 
C 2 544  ASN 544  544  544 ASN ASN A . n 
C 2 545  GLY 545  545  545 GLY GLY A . n 
C 2 546  LEU 546  546  546 LEU LEU A . n 
C 2 547  THR 547  547  547 THR THR A . n 
C 2 548  GLY 548  548  548 GLY GLY A . n 
C 2 549  THR 549  549  549 THR THR A . n 
C 2 550  GLY 550  550  550 GLY GLY A . n 
C 2 551  VAL 551  551  551 VAL VAL A . n 
C 2 552  LEU 552  552  552 LEU LEU A . n 
C 2 553  THR 553  553  553 THR THR A . n 
C 2 554  GLU 554  554  554 GLU GLU A . n 
C 2 555  SER 555  555  555 SER SER A . n 
C 2 556  ASN 556  556  556 ASN ASN A . n 
C 2 557  LYS 557  557  557 LYS LYS A . n 
C 2 558  LYS 558  558  558 LYS LYS A . n 
C 2 559  PHE 559  559  559 PHE PHE A . n 
C 2 560  LEU 560  560  560 LEU LEU A . n 
C 2 561  PRO 561  561  561 PRO PRO A . n 
C 2 562  PHE 562  562  562 PHE PHE A . n 
C 2 563  GLN 563  563  563 GLN GLN A . n 
C 2 564  GLN 564  564  564 GLN GLN A . n 
C 2 565  PHE 565  565  565 PHE PHE A . n 
C 2 566  GLY 566  566  566 GLY GLY A . n 
C 2 567  ARG 567  567  567 ARG ARG A . n 
C 2 568  ASP 568  568  568 ASP ASP A . n 
C 2 569  ILE 569  569  569 ILE ILE A . n 
C 2 570  ALA 570  570  570 ALA ALA A . n 
C 2 571  ASP 571  571  571 ASP ASP A . n 
C 2 572  THR 572  572  572 THR THR A . n 
C 2 573  THR 573  573  573 THR THR A . n 
C 2 574  ASP 574  574  574 ASP ASP A . n 
C 2 575  ALA 575  575  575 ALA ALA A . n 
C 2 576  VAL 576  576  576 VAL VAL A . n 
C 2 577  ARG 577  577  577 ARG ARG A . n 
C 2 578  ASP 578  578  578 ASP ASP A . n 
C 2 579  PRO 579  579  579 PRO PRO A . n 
C 2 580  GLN 580  580  580 GLN GLN A . n 
C 2 581  THR 581  581  581 THR THR A . n 
C 2 582  LEU 582  582  582 LEU LEU A . n 
C 2 583  GLU 583  583  583 GLU GLU A . n 
C 2 584  ILE 584  584  584 ILE ILE A . n 
C 2 585  LEU 585  585  585 LEU LEU A . n 
C 2 586  ASP 586  586  586 ASP ASP A . n 
C 2 587  ILE 587  587  587 ILE ILE A . n 
C 2 588  THR 588  588  588 THR THR A . n 
C 2 589  PRO 589  589  589 PRO PRO A . n 
C 2 590  CYS 590  590  590 CYS CYS A . n 
C 2 591  SER 591  591  591 SER SER A . n 
C 2 592  PHE 592  592  592 PHE PHE A . n 
C 2 593  GLY 593  593  ?   ?   ?   A . n 
C 2 594  GLY 594  594  ?   ?   ?   A . n 
C 2 595  VAL 595  595  ?   ?   ?   A . n 
C 2 596  SER 596  596  ?   ?   ?   A . n 
C 2 597  VAL 597  597  ?   ?   ?   A . n 
C 2 598  ILE 598  598  ?   ?   ?   A . n 
C 2 599  THR 599  599  ?   ?   ?   A . n 
C 2 600  PRO 600  600  ?   ?   ?   A . n 
C 2 601  GLY 601  601  ?   ?   ?   A . n 
C 2 602  THR 602  602  ?   ?   ?   A . n 
C 2 603  ASN 603  603  ?   ?   ?   A . n 
C 2 604  THR 604  604  ?   ?   ?   A . n 
C 2 605  SER 605  605  ?   ?   ?   A . n 
C 2 606  ASN 606  606  ?   ?   ?   A . n 
C 2 607  GLN 607  607  ?   ?   ?   A . n 
C 2 608  VAL 608  608  ?   ?   ?   A . n 
C 2 609  ALA 609  609  ?   ?   ?   A . n 
C 2 610  VAL 610  610  ?   ?   ?   A . n 
C 2 611  LEU 611  611  ?   ?   ?   A . n 
C 2 612  TYR 612  612  ?   ?   ?   A . n 
C 2 613  GLN 613  613  ?   ?   ?   A . n 
C 2 614  GLY 614  614  ?   ?   ?   A . n 
C 2 615  VAL 615  615  ?   ?   ?   A . n 
C 2 616  ASN 616  616  ?   ?   ?   A . n 
C 2 617  CYS 617  617  ?   ?   ?   A . n 
C 2 618  THR 618  618  ?   ?   ?   A . n 
C 2 619  GLU 619  619  ?   ?   ?   A . n 
C 2 620  VAL 620  620  ?   ?   ?   A . n 
C 2 621  PRO 621  621  ?   ?   ?   A . n 
C 2 622  VAL 622  622  ?   ?   ?   A . n 
C 2 623  ALA 623  623  ?   ?   ?   A . n 
C 2 624  ILE 624  624  ?   ?   ?   A . n 
C 2 625  HIS 625  625  ?   ?   ?   A . n 
C 2 626  ALA 626  626  ?   ?   ?   A . n 
C 2 627  ASP 627  627  ?   ?   ?   A . n 
C 2 628  GLN 628  628  ?   ?   ?   A . n 
C 2 629  LEU 629  629  ?   ?   ?   A . n 
C 2 630  THR 630  630  ?   ?   ?   A . n 
C 2 631  PRO 631  631  ?   ?   ?   A . n 
C 2 632  THR 632  632  ?   ?   ?   A . n 
C 2 633  TRP 633  633  ?   ?   ?   A . n 
C 2 634  ARG 634  634  ?   ?   ?   A . n 
C 2 635  VAL 635  635  ?   ?   ?   A . n 
C 2 636  TYR 636  636  ?   ?   ?   A . n 
C 2 637  SER 637  637  ?   ?   ?   A . n 
C 2 638  THR 638  638  ?   ?   ?   A . n 
C 2 639  GLY 639  639  ?   ?   ?   A . n 
C 2 640  SER 640  640  ?   ?   ?   A . n 
C 2 641  ASN 641  641  ?   ?   ?   A . n 
C 2 642  VAL 642  642  ?   ?   ?   A . n 
C 2 643  PHE 643  643  ?   ?   ?   A . n 
C 2 644  GLN 644  644  ?   ?   ?   A . n 
C 2 645  THR 645  645  ?   ?   ?   A . n 
C 2 646  ARG 646  646  ?   ?   ?   A . n 
C 2 647  ALA 647  647  ?   ?   ?   A . n 
C 2 648  GLY 648  648  ?   ?   ?   A . n 
C 2 649  CYS 649  649  ?   ?   ?   A . n 
C 2 650  LEU 650  650  ?   ?   ?   A . n 
C 2 651  ILE 651  651  ?   ?   ?   A . n 
C 2 652  GLY 652  652  ?   ?   ?   A . n 
C 2 653  ALA 653  653  ?   ?   ?   A . n 
C 2 654  GLU 654  654  ?   ?   ?   A . n 
C 2 655  HIS 655  655  ?   ?   ?   A . n 
C 2 656  VAL 656  656  ?   ?   ?   A . n 
C 2 657  ASN 657  657  ?   ?   ?   A . n 
C 2 658  ASN 658  658  ?   ?   ?   A . n 
C 2 659  SER 659  659  ?   ?   ?   A . n 
C 2 660  TYR 660  660  ?   ?   ?   A . n 
C 2 661  GLU 661  661  ?   ?   ?   A . n 
C 2 662  CYS 662  662  ?   ?   ?   A . n 
C 2 663  ASP 663  663  ?   ?   ?   A . n 
C 2 664  ILE 664  664  ?   ?   ?   A . n 
C 2 665  PRO 665  665  ?   ?   ?   A . n 
C 2 666  ILE 666  666  ?   ?   ?   A . n 
C 2 667  GLY 667  667  ?   ?   ?   A . n 
C 2 668  ALA 668  668  ?   ?   ?   A . n 
C 2 669  GLY 669  669  ?   ?   ?   A . n 
C 2 670  ILE 670  670  ?   ?   ?   A . n 
C 2 671  CYS 671  671  ?   ?   ?   A . n 
C 2 672  ALA 672  672  ?   ?   ?   A . n 
C 2 673  SER 673  673  ?   ?   ?   A . n 
C 2 674  TYR 674  674  ?   ?   ?   A . n 
C 2 675  GLN 675  675  ?   ?   ?   A . n 
C 2 676  THR 676  676  ?   ?   ?   A . n 
C 2 677  GLN 677  677  ?   ?   ?   A . n 
C 2 678  THR 678  678  ?   ?   ?   A . n 
C 2 679  ASN 679  679  ?   ?   ?   A . n 
C 2 680  SER 680  680  ?   ?   ?   A . n 
C 2 681  PRO 681  681  ?   ?   ?   A . n 
C 2 682  ARG 682  682  ?   ?   ?   A . n 
C 2 683  ARG 683  683  ?   ?   ?   A . n 
C 2 684  ALA 684  684  ?   ?   ?   A . n 
C 2 685  ARG 685  685  ?   ?   ?   A . n 
C 2 686  SER 686  686  ?   ?   ?   A . n 
C 2 687  VAL 687  687  ?   ?   ?   A . n 
C 2 688  ALA 688  688  ?   ?   ?   A . n 
C 2 689  SER 689  689  ?   ?   ?   A . n 
C 2 690  GLN 690  690  ?   ?   ?   A . n 
C 2 691  SER 691  691  ?   ?   ?   A . n 
C 2 692  ILE 692  692  ?   ?   ?   A . n 
C 2 693  ILE 693  693  ?   ?   ?   A . n 
C 2 694  ALA 694  694  ?   ?   ?   A . n 
C 2 695  TYR 695  695  ?   ?   ?   A . n 
C 2 696  THR 696  696  ?   ?   ?   A . n 
C 2 697  MET 697  697  ?   ?   ?   A . n 
C 2 698  SER 698  698  ?   ?   ?   A . n 
C 2 699  LEU 699  699  ?   ?   ?   A . n 
C 2 700  GLY 700  700  ?   ?   ?   A . n 
C 2 701  ALA 701  701  ?   ?   ?   A . n 
C 2 702  GLU 702  702  ?   ?   ?   A . n 
C 2 703  ASN 703  703  ?   ?   ?   A . n 
C 2 704  SER 704  704  ?   ?   ?   A . n 
C 2 705  VAL 705  705  ?   ?   ?   A . n 
C 2 706  ALA 706  706  ?   ?   ?   A . n 
C 2 707  TYR 707  707  ?   ?   ?   A . n 
C 2 708  SER 708  708  ?   ?   ?   A . n 
C 2 709  ASN 709  709  ?   ?   ?   A . n 
C 2 710  ASN 710  710  ?   ?   ?   A . n 
C 2 711  SER 711  711  ?   ?   ?   A . n 
C 2 712  ILE 712  712  ?   ?   ?   A . n 
C 2 713  ALA 713  713  ?   ?   ?   A . n 
C 2 714  ILE 714  714  ?   ?   ?   A . n 
C 2 715  PRO 715  715  ?   ?   ?   A . n 
C 2 716  THR 716  716  ?   ?   ?   A . n 
C 2 717  ASN 717  717  ?   ?   ?   A . n 
C 2 718  PHE 718  718  ?   ?   ?   A . n 
C 2 719  THR 719  719  ?   ?   ?   A . n 
C 2 720  ILE 720  720  ?   ?   ?   A . n 
C 2 721  SER 721  721  ?   ?   ?   A . n 
C 2 722  VAL 722  722  ?   ?   ?   A . n 
C 2 723  THR 723  723  ?   ?   ?   A . n 
C 2 724  THR 724  724  ?   ?   ?   A . n 
C 2 725  GLU 725  725  ?   ?   ?   A . n 
C 2 726  ILE 726  726  ?   ?   ?   A . n 
C 2 727  LEU 727  727  ?   ?   ?   A . n 
C 2 728  PRO 728  728  ?   ?   ?   A . n 
C 2 729  VAL 729  729  ?   ?   ?   A . n 
C 2 730  SER 730  730  ?   ?   ?   A . n 
C 2 731  MET 731  731  ?   ?   ?   A . n 
C 2 732  THR 732  732  ?   ?   ?   A . n 
C 2 733  LYS 733  733  ?   ?   ?   A . n 
C 2 734  THR 734  734  ?   ?   ?   A . n 
C 2 735  SER 735  735  ?   ?   ?   A . n 
C 2 736  VAL 736  736  ?   ?   ?   A . n 
C 2 737  ASP 737  737  ?   ?   ?   A . n 
C 2 738  CYS 738  738  ?   ?   ?   A . n 
C 2 739  THR 739  739  ?   ?   ?   A . n 
C 2 740  MET 740  740  ?   ?   ?   A . n 
C 2 741  TYR 741  741  ?   ?   ?   A . n 
C 2 742  ILE 742  742  ?   ?   ?   A . n 
C 2 743  CYS 743  743  ?   ?   ?   A . n 
C 2 744  GLY 744  744  ?   ?   ?   A . n 
C 2 745  ASP 745  745  ?   ?   ?   A . n 
C 2 746  SER 746  746  ?   ?   ?   A . n 
C 2 747  THR 747  747  ?   ?   ?   A . n 
C 2 748  GLU 748  748  ?   ?   ?   A . n 
C 2 749  CYS 749  749  ?   ?   ?   A . n 
C 2 750  SER 750  750  ?   ?   ?   A . n 
C 2 751  ASN 751  751  ?   ?   ?   A . n 
C 2 752  LEU 752  752  ?   ?   ?   A . n 
C 2 753  LEU 753  753  ?   ?   ?   A . n 
C 2 754  LEU 754  754  ?   ?   ?   A . n 
C 2 755  GLN 755  755  ?   ?   ?   A . n 
C 2 756  TYR 756  756  ?   ?   ?   A . n 
C 2 757  GLY 757  757  ?   ?   ?   A . n 
C 2 758  SER 758  758  ?   ?   ?   A . n 
C 2 759  PHE 759  759  ?   ?   ?   A . n 
C 2 760  CYS 760  760  ?   ?   ?   A . n 
C 2 761  THR 761  761  ?   ?   ?   A . n 
C 2 762  GLN 762  762  ?   ?   ?   A . n 
C 2 763  LEU 763  763  ?   ?   ?   A . n 
C 2 764  ASN 764  764  ?   ?   ?   A . n 
C 2 765  ARG 765  765  ?   ?   ?   A . n 
C 2 766  ALA 766  766  ?   ?   ?   A . n 
C 2 767  LEU 767  767  ?   ?   ?   A . n 
C 2 768  THR 768  768  ?   ?   ?   A . n 
C 2 769  GLY 769  769  ?   ?   ?   A . n 
C 2 770  ILE 770  770  ?   ?   ?   A . n 
C 2 771  ALA 771  771  ?   ?   ?   A . n 
C 2 772  VAL 772  772  ?   ?   ?   A . n 
C 2 773  GLU 773  773  ?   ?   ?   A . n 
C 2 774  GLN 774  774  ?   ?   ?   A . n 
C 2 775  ASP 775  775  ?   ?   ?   A . n 
C 2 776  LYS 776  776  ?   ?   ?   A . n 
C 2 777  ASN 777  777  ?   ?   ?   A . n 
C 2 778  THR 778  778  ?   ?   ?   A . n 
C 2 779  GLN 779  779  ?   ?   ?   A . n 
C 2 780  GLU 780  780  ?   ?   ?   A . n 
C 2 781  VAL 781  781  ?   ?   ?   A . n 
C 2 782  PHE 782  782  ?   ?   ?   A . n 
C 2 783  ALA 783  783  ?   ?   ?   A . n 
C 2 784  GLN 784  784  ?   ?   ?   A . n 
C 2 785  VAL 785  785  ?   ?   ?   A . n 
C 2 786  LYS 786  786  ?   ?   ?   A . n 
C 2 787  GLN 787  787  ?   ?   ?   A . n 
C 2 788  ILE 788  788  ?   ?   ?   A . n 
C 2 789  TYR 789  789  ?   ?   ?   A . n 
C 2 790  LYS 790  790  ?   ?   ?   A . n 
C 2 791  THR 791  791  ?   ?   ?   A . n 
C 2 792  PRO 792  792  ?   ?   ?   A . n 
C 2 793  PRO 793  793  ?   ?   ?   A . n 
C 2 794  ILE 794  794  ?   ?   ?   A . n 
C 2 795  LYS 795  795  ?   ?   ?   A . n 
C 2 796  ASP 796  796  ?   ?   ?   A . n 
C 2 797  PHE 797  797  ?   ?   ?   A . n 
C 2 798  GLY 798  798  ?   ?   ?   A . n 
C 2 799  GLY 799  799  ?   ?   ?   A . n 
C 2 800  PHE 800  800  ?   ?   ?   A . n 
C 2 801  ASN 801  801  ?   ?   ?   A . n 
C 2 802  PHE 802  802  ?   ?   ?   A . n 
C 2 803  SER 803  803  ?   ?   ?   A . n 
C 2 804  GLN 804  804  ?   ?   ?   A . n 
C 2 805  ILE 805  805  ?   ?   ?   A . n 
C 2 806  LEU 806  806  ?   ?   ?   A . n 
C 2 807  PRO 807  807  ?   ?   ?   A . n 
C 2 808  ASP 808  808  ?   ?   ?   A . n 
C 2 809  PRO 809  809  ?   ?   ?   A . n 
C 2 810  SER 810  810  ?   ?   ?   A . n 
C 2 811  LYS 811  811  ?   ?   ?   A . n 
C 2 812  PRO 812  812  ?   ?   ?   A . n 
C 2 813  SER 813  813  ?   ?   ?   A . n 
C 2 814  LYS 814  814  ?   ?   ?   A . n 
C 2 815  ARG 815  815  ?   ?   ?   A . n 
C 2 816  SER 816  816  ?   ?   ?   A . n 
C 2 817  PHE 817  817  ?   ?   ?   A . n 
C 2 818  ILE 818  818  ?   ?   ?   A . n 
C 2 819  GLU 819  819  ?   ?   ?   A . n 
C 2 820  ASP 820  820  ?   ?   ?   A . n 
C 2 821  LEU 821  821  ?   ?   ?   A . n 
C 2 822  LEU 822  822  ?   ?   ?   A . n 
C 2 823  PHE 823  823  ?   ?   ?   A . n 
C 2 824  ASN 824  824  ?   ?   ?   A . n 
C 2 825  LYS 825  825  ?   ?   ?   A . n 
C 2 826  VAL 826  826  ?   ?   ?   A . n 
C 2 827  THR 827  827  ?   ?   ?   A . n 
C 2 828  LEU 828  828  ?   ?   ?   A . n 
C 2 829  ALA 829  829  ?   ?   ?   A . n 
C 2 830  ASP 830  830  ?   ?   ?   A . n 
C 2 831  ALA 831  831  ?   ?   ?   A . n 
C 2 832  GLY 832  832  ?   ?   ?   A . n 
C 2 833  PHE 833  833  ?   ?   ?   A . n 
C 2 834  ILE 834  834  ?   ?   ?   A . n 
C 2 835  LYS 835  835  ?   ?   ?   A . n 
C 2 836  GLN 836  836  ?   ?   ?   A . n 
C 2 837  TYR 837  837  ?   ?   ?   A . n 
C 2 838  GLY 838  838  ?   ?   ?   A . n 
C 2 839  ASP 839  839  ?   ?   ?   A . n 
C 2 840  CYS 840  840  ?   ?   ?   A . n 
C 2 841  LEU 841  841  ?   ?   ?   A . n 
C 2 842  GLY 842  842  ?   ?   ?   A . n 
C 2 843  ASP 843  843  ?   ?   ?   A . n 
C 2 844  ILE 844  844  ?   ?   ?   A . n 
C 2 845  ALA 845  845  ?   ?   ?   A . n 
C 2 846  ALA 846  846  ?   ?   ?   A . n 
C 2 847  ARG 847  847  ?   ?   ?   A . n 
C 2 848  ASP 848  848  ?   ?   ?   A . n 
C 2 849  LEU 849  849  ?   ?   ?   A . n 
C 2 850  ILE 850  850  ?   ?   ?   A . n 
C 2 851  CYS 851  851  ?   ?   ?   A . n 
C 2 852  ALA 852  852  ?   ?   ?   A . n 
C 2 853  GLN 853  853  ?   ?   ?   A . n 
C 2 854  LYS 854  854  ?   ?   ?   A . n 
C 2 855  PHE 855  855  ?   ?   ?   A . n 
C 2 856  ASN 856  856  ?   ?   ?   A . n 
C 2 857  GLY 857  857  ?   ?   ?   A . n 
C 2 858  LEU 858  858  ?   ?   ?   A . n 
C 2 859  THR 859  859  ?   ?   ?   A . n 
C 2 860  VAL 860  860  ?   ?   ?   A . n 
C 2 861  LEU 861  861  ?   ?   ?   A . n 
C 2 862  PRO 862  862  ?   ?   ?   A . n 
C 2 863  PRO 863  863  ?   ?   ?   A . n 
C 2 864  LEU 864  864  ?   ?   ?   A . n 
C 2 865  LEU 865  865  ?   ?   ?   A . n 
C 2 866  THR 866  866  ?   ?   ?   A . n 
C 2 867  ASP 867  867  ?   ?   ?   A . n 
C 2 868  GLU 868  868  ?   ?   ?   A . n 
C 2 869  MET 869  869  ?   ?   ?   A . n 
C 2 870  ILE 870  870  ?   ?   ?   A . n 
C 2 871  ALA 871  871  ?   ?   ?   A . n 
C 2 872  GLN 872  872  ?   ?   ?   A . n 
C 2 873  TYR 873  873  ?   ?   ?   A . n 
C 2 874  THR 874  874  ?   ?   ?   A . n 
C 2 875  SER 875  875  ?   ?   ?   A . n 
C 2 876  ALA 876  876  ?   ?   ?   A . n 
C 2 877  LEU 877  877  ?   ?   ?   A . n 
C 2 878  LEU 878  878  ?   ?   ?   A . n 
C 2 879  ALA 879  879  ?   ?   ?   A . n 
C 2 880  GLY 880  880  ?   ?   ?   A . n 
C 2 881  THR 881  881  ?   ?   ?   A . n 
C 2 882  ILE 882  882  ?   ?   ?   A . n 
C 2 883  THR 883  883  ?   ?   ?   A . n 
C 2 884  SER 884  884  ?   ?   ?   A . n 
C 2 885  GLY 885  885  ?   ?   ?   A . n 
C 2 886  TRP 886  886  ?   ?   ?   A . n 
C 2 887  THR 887  887  ?   ?   ?   A . n 
C 2 888  PHE 888  888  ?   ?   ?   A . n 
C 2 889  GLY 889  889  ?   ?   ?   A . n 
C 2 890  ALA 890  890  ?   ?   ?   A . n 
C 2 891  GLY 891  891  ?   ?   ?   A . n 
C 2 892  ALA 892  892  ?   ?   ?   A . n 
C 2 893  ALA 893  893  ?   ?   ?   A . n 
C 2 894  LEU 894  894  ?   ?   ?   A . n 
C 2 895  GLN 895  895  ?   ?   ?   A . n 
C 2 896  ILE 896  896  ?   ?   ?   A . n 
C 2 897  PRO 897  897  ?   ?   ?   A . n 
C 2 898  PHE 898  898  ?   ?   ?   A . n 
C 2 899  ALA 899  899  ?   ?   ?   A . n 
C 2 900  MET 900  900  ?   ?   ?   A . n 
C 2 901  GLN 901  901  ?   ?   ?   A . n 
C 2 902  MET 902  902  ?   ?   ?   A . n 
C 2 903  ALA 903  903  ?   ?   ?   A . n 
C 2 904  TYR 904  904  ?   ?   ?   A . n 
C 2 905  ARG 905  905  ?   ?   ?   A . n 
C 2 906  PHE 906  906  ?   ?   ?   A . n 
C 2 907  ASN 907  907  ?   ?   ?   A . n 
C 2 908  GLY 908  908  ?   ?   ?   A . n 
C 2 909  ILE 909  909  ?   ?   ?   A . n 
C 2 910  GLY 910  910  ?   ?   ?   A . n 
C 2 911  VAL 911  911  ?   ?   ?   A . n 
C 2 912  THR 912  912  ?   ?   ?   A . n 
C 2 913  GLN 913  913  ?   ?   ?   A . n 
C 2 914  ASN 914  914  ?   ?   ?   A . n 
C 2 915  VAL 915  915  ?   ?   ?   A . n 
C 2 916  LEU 916  916  ?   ?   ?   A . n 
C 2 917  TYR 917  917  ?   ?   ?   A . n 
C 2 918  GLU 918  918  ?   ?   ?   A . n 
C 2 919  ASN 919  919  ?   ?   ?   A . n 
C 2 920  GLN 920  920  ?   ?   ?   A . n 
C 2 921  LYS 921  921  ?   ?   ?   A . n 
C 2 922  LEU 922  922  ?   ?   ?   A . n 
C 2 923  ILE 923  923  ?   ?   ?   A . n 
C 2 924  ALA 924  924  ?   ?   ?   A . n 
C 2 925  ASN 925  925  ?   ?   ?   A . n 
C 2 926  GLN 926  926  ?   ?   ?   A . n 
C 2 927  PHE 927  927  ?   ?   ?   A . n 
C 2 928  ASN 928  928  ?   ?   ?   A . n 
C 2 929  SER 929  929  ?   ?   ?   A . n 
C 2 930  ALA 930  930  ?   ?   ?   A . n 
C 2 931  ILE 931  931  ?   ?   ?   A . n 
C 2 932  GLY 932  932  ?   ?   ?   A . n 
C 2 933  LYS 933  933  ?   ?   ?   A . n 
C 2 934  ILE 934  934  ?   ?   ?   A . n 
C 2 935  GLN 935  935  ?   ?   ?   A . n 
C 2 936  ASP 936  936  ?   ?   ?   A . n 
C 2 937  SER 937  937  ?   ?   ?   A . n 
C 2 938  LEU 938  938  ?   ?   ?   A . n 
C 2 939  SER 939  939  ?   ?   ?   A . n 
C 2 940  SER 940  940  ?   ?   ?   A . n 
C 2 941  THR 941  941  ?   ?   ?   A . n 
C 2 942  ALA 942  942  ?   ?   ?   A . n 
C 2 943  SER 943  943  ?   ?   ?   A . n 
C 2 944  ALA 944  944  ?   ?   ?   A . n 
C 2 945  LEU 945  945  ?   ?   ?   A . n 
C 2 946  GLY 946  946  ?   ?   ?   A . n 
C 2 947  LYS 947  947  ?   ?   ?   A . n 
C 2 948  LEU 948  948  ?   ?   ?   A . n 
C 2 949  GLN 949  949  ?   ?   ?   A . n 
C 2 950  ASP 950  950  ?   ?   ?   A . n 
C 2 951  VAL 951  951  ?   ?   ?   A . n 
C 2 952  VAL 952  952  ?   ?   ?   A . n 
C 2 953  ASN 953  953  ?   ?   ?   A . n 
C 2 954  GLN 954  954  ?   ?   ?   A . n 
C 2 955  ASN 955  955  ?   ?   ?   A . n 
C 2 956  ALA 956  956  ?   ?   ?   A . n 
C 2 957  GLN 957  957  ?   ?   ?   A . n 
C 2 958  ALA 958  958  ?   ?   ?   A . n 
C 2 959  LEU 959  959  ?   ?   ?   A . n 
C 2 960  ASN 960  960  ?   ?   ?   A . n 
C 2 961  THR 961  961  ?   ?   ?   A . n 
C 2 962  LEU 962  962  ?   ?   ?   A . n 
C 2 963  VAL 963  963  ?   ?   ?   A . n 
C 2 964  LYS 964  964  ?   ?   ?   A . n 
C 2 965  GLN 965  965  ?   ?   ?   A . n 
C 2 966  LEU 966  966  ?   ?   ?   A . n 
C 2 967  SER 967  967  ?   ?   ?   A . n 
C 2 968  SER 968  968  ?   ?   ?   A . n 
C 2 969  ASN 969  969  ?   ?   ?   A . n 
C 2 970  PHE 970  970  ?   ?   ?   A . n 
C 2 971  GLY 971  971  ?   ?   ?   A . n 
C 2 972  ALA 972  972  ?   ?   ?   A . n 
C 2 973  ILE 973  973  ?   ?   ?   A . n 
C 2 974  SER 974  974  ?   ?   ?   A . n 
C 2 975  SER 975  975  ?   ?   ?   A . n 
C 2 976  VAL 976  976  ?   ?   ?   A . n 
C 2 977  LEU 977  977  ?   ?   ?   A . n 
C 2 978  ASN 978  978  ?   ?   ?   A . n 
C 2 979  ASP 979  979  ?   ?   ?   A . n 
C 2 980  ILE 980  980  ?   ?   ?   A . n 
C 2 981  LEU 981  981  ?   ?   ?   A . n 
C 2 982  SER 982  982  ?   ?   ?   A . n 
C 2 983  ARG 983  983  ?   ?   ?   A . n 
C 2 984  LEU 984  984  ?   ?   ?   A . n 
C 2 985  ASP 985  985  ?   ?   ?   A . n 
C 2 986  LYS 986  986  ?   ?   ?   A . n 
C 2 987  VAL 987  987  ?   ?   ?   A . n 
C 2 988  GLU 988  988  ?   ?   ?   A . n 
C 2 989  ALA 989  989  ?   ?   ?   A . n 
C 2 990  GLU 990  990  ?   ?   ?   A . n 
C 2 991  VAL 991  991  ?   ?   ?   A . n 
C 2 992  GLN 992  992  ?   ?   ?   A . n 
C 2 993  ILE 993  993  ?   ?   ?   A . n 
C 2 994  ASP 994  994  ?   ?   ?   A . n 
C 2 995  ARG 995  995  ?   ?   ?   A . n 
C 2 996  LEU 996  996  ?   ?   ?   A . n 
C 2 997  ILE 997  997  ?   ?   ?   A . n 
C 2 998  THR 998  998  ?   ?   ?   A . n 
C 2 999  GLY 999  999  ?   ?   ?   A . n 
C 2 1000 ARG 1000 1000 ?   ?   ?   A . n 
C 2 1001 LEU 1001 1001 ?   ?   ?   A . n 
C 2 1002 GLN 1002 1002 ?   ?   ?   A . n 
C 2 1003 SER 1003 1003 ?   ?   ?   A . n 
C 2 1004 LEU 1004 1004 ?   ?   ?   A . n 
C 2 1005 GLN 1005 1005 ?   ?   ?   A . n 
C 2 1006 THR 1006 1006 ?   ?   ?   A . n 
C 2 1007 TYR 1007 1007 ?   ?   ?   A . n 
C 2 1008 VAL 1008 1008 ?   ?   ?   A . n 
C 2 1009 THR 1009 1009 ?   ?   ?   A . n 
C 2 1010 GLN 1010 1010 ?   ?   ?   A . n 
C 2 1011 GLN 1011 1011 ?   ?   ?   A . n 
C 2 1012 LEU 1012 1012 ?   ?   ?   A . n 
C 2 1013 ILE 1013 1013 ?   ?   ?   A . n 
C 2 1014 ARG 1014 1014 ?   ?   ?   A . n 
C 2 1015 ALA 1015 1015 ?   ?   ?   A . n 
C 2 1016 ALA 1016 1016 ?   ?   ?   A . n 
C 2 1017 GLU 1017 1017 ?   ?   ?   A . n 
C 2 1018 ILE 1018 1018 ?   ?   ?   A . n 
C 2 1019 ARG 1019 1019 ?   ?   ?   A . n 
C 2 1020 ALA 1020 1020 ?   ?   ?   A . n 
C 2 1021 SER 1021 1021 ?   ?   ?   A . n 
C 2 1022 ALA 1022 1022 ?   ?   ?   A . n 
C 2 1023 ASN 1023 1023 ?   ?   ?   A . n 
C 2 1024 LEU 1024 1024 ?   ?   ?   A . n 
C 2 1025 ALA 1025 1025 ?   ?   ?   A . n 
C 2 1026 ALA 1026 1026 ?   ?   ?   A . n 
C 2 1027 THR 1027 1027 ?   ?   ?   A . n 
C 2 1028 LYS 1028 1028 ?   ?   ?   A . n 
C 2 1029 MET 1029 1029 ?   ?   ?   A . n 
C 2 1030 SER 1030 1030 ?   ?   ?   A . n 
C 2 1031 GLU 1031 1031 ?   ?   ?   A . n 
C 2 1032 CYS 1032 1032 ?   ?   ?   A . n 
C 2 1033 VAL 1033 1033 ?   ?   ?   A . n 
C 2 1034 LEU 1034 1034 ?   ?   ?   A . n 
C 2 1035 GLY 1035 1035 ?   ?   ?   A . n 
C 2 1036 GLN 1036 1036 ?   ?   ?   A . n 
C 2 1037 SER 1037 1037 ?   ?   ?   A . n 
C 2 1038 LYS 1038 1038 ?   ?   ?   A . n 
C 2 1039 ARG 1039 1039 ?   ?   ?   A . n 
C 2 1040 VAL 1040 1040 ?   ?   ?   A . n 
C 2 1041 ASP 1041 1041 ?   ?   ?   A . n 
C 2 1042 PHE 1042 1042 ?   ?   ?   A . n 
C 2 1043 CYS 1043 1043 ?   ?   ?   A . n 
C 2 1044 GLY 1044 1044 ?   ?   ?   A . n 
C 2 1045 LYS 1045 1045 ?   ?   ?   A . n 
C 2 1046 GLY 1046 1046 ?   ?   ?   A . n 
C 2 1047 TYR 1047 1047 ?   ?   ?   A . n 
C 2 1048 HIS 1048 1048 ?   ?   ?   A . n 
C 2 1049 LEU 1049 1049 ?   ?   ?   A . n 
C 2 1050 MET 1050 1050 ?   ?   ?   A . n 
C 2 1051 SER 1051 1051 ?   ?   ?   A . n 
C 2 1052 PHE 1052 1052 ?   ?   ?   A . n 
C 2 1053 PRO 1053 1053 ?   ?   ?   A . n 
C 2 1054 GLN 1054 1054 ?   ?   ?   A . n 
C 2 1055 SER 1055 1055 ?   ?   ?   A . n 
C 2 1056 ALA 1056 1056 ?   ?   ?   A . n 
C 2 1057 PRO 1057 1057 ?   ?   ?   A . n 
C 2 1058 HIS 1058 1058 ?   ?   ?   A . n 
C 2 1059 GLY 1059 1059 ?   ?   ?   A . n 
C 2 1060 VAL 1060 1060 ?   ?   ?   A . n 
C 2 1061 VAL 1061 1061 ?   ?   ?   A . n 
C 2 1062 PHE 1062 1062 ?   ?   ?   A . n 
C 2 1063 LEU 1063 1063 ?   ?   ?   A . n 
C 2 1064 HIS 1064 1064 ?   ?   ?   A . n 
C 2 1065 VAL 1065 1065 ?   ?   ?   A . n 
C 2 1066 THR 1066 1066 ?   ?   ?   A . n 
C 2 1067 TYR 1067 1067 ?   ?   ?   A . n 
C 2 1068 VAL 1068 1068 ?   ?   ?   A . n 
C 2 1069 PRO 1069 1069 ?   ?   ?   A . n 
C 2 1070 ALA 1070 1070 ?   ?   ?   A . n 
C 2 1071 GLN 1071 1071 ?   ?   ?   A . n 
C 2 1072 GLU 1072 1072 ?   ?   ?   A . n 
C 2 1073 LYS 1073 1073 ?   ?   ?   A . n 
C 2 1074 ASN 1074 1074 ?   ?   ?   A . n 
C 2 1075 PHE 1075 1075 ?   ?   ?   A . n 
C 2 1076 THR 1076 1076 ?   ?   ?   A . n 
C 2 1077 THR 1077 1077 ?   ?   ?   A . n 
C 2 1078 ALA 1078 1078 ?   ?   ?   A . n 
C 2 1079 PRO 1079 1079 ?   ?   ?   A . n 
C 2 1080 ALA 1080 1080 ?   ?   ?   A . n 
C 2 1081 ILE 1081 1081 ?   ?   ?   A . n 
C 2 1082 CYS 1082 1082 ?   ?   ?   A . n 
C 2 1083 HIS 1083 1083 ?   ?   ?   A . n 
C 2 1084 ASP 1084 1084 ?   ?   ?   A . n 
C 2 1085 GLY 1085 1085 ?   ?   ?   A . n 
C 2 1086 LYS 1086 1086 ?   ?   ?   A . n 
C 2 1087 ALA 1087 1087 ?   ?   ?   A . n 
C 2 1088 HIS 1088 1088 ?   ?   ?   A . n 
C 2 1089 PHE 1089 1089 ?   ?   ?   A . n 
C 2 1090 PRO 1090 1090 ?   ?   ?   A . n 
C 2 1091 ARG 1091 1091 ?   ?   ?   A . n 
C 2 1092 GLU 1092 1092 ?   ?   ?   A . n 
C 2 1093 GLY 1093 1093 ?   ?   ?   A . n 
C 2 1094 VAL 1094 1094 ?   ?   ?   A . n 
C 2 1095 PHE 1095 1095 ?   ?   ?   A . n 
C 2 1096 VAL 1096 1096 ?   ?   ?   A . n 
C 2 1097 SER 1097 1097 ?   ?   ?   A . n 
C 2 1098 ASN 1098 1098 ?   ?   ?   A . n 
C 2 1099 GLY 1099 1099 ?   ?   ?   A . n 
C 2 1100 THR 1100 1100 ?   ?   ?   A . n 
C 2 1101 HIS 1101 1101 ?   ?   ?   A . n 
C 2 1102 TRP 1102 1102 ?   ?   ?   A . n 
C 2 1103 PHE 1103 1103 ?   ?   ?   A . n 
C 2 1104 VAL 1104 1104 ?   ?   ?   A . n 
C 2 1105 THR 1105 1105 ?   ?   ?   A . n 
C 2 1106 GLN 1106 1106 ?   ?   ?   A . n 
C 2 1107 ARG 1107 1107 ?   ?   ?   A . n 
C 2 1108 ASN 1108 1108 ?   ?   ?   A . n 
C 2 1109 PHE 1109 1109 ?   ?   ?   A . n 
C 2 1110 TYR 1110 1110 ?   ?   ?   A . n 
C 2 1111 GLU 1111 1111 ?   ?   ?   A . n 
C 2 1112 PRO 1112 1112 ?   ?   ?   A . n 
C 2 1113 GLN 1113 1113 ?   ?   ?   A . n 
C 2 1114 ILE 1114 1114 ?   ?   ?   A . n 
C 2 1115 ILE 1115 1115 ?   ?   ?   A . n 
C 2 1116 THR 1116 1116 ?   ?   ?   A . n 
C 2 1117 THR 1117 1117 ?   ?   ?   A . n 
C 2 1118 ASP 1118 1118 ?   ?   ?   A . n 
C 2 1119 ASN 1119 1119 ?   ?   ?   A . n 
C 2 1120 THR 1120 1120 ?   ?   ?   A . n 
C 2 1121 PHE 1121 1121 ?   ?   ?   A . n 
C 2 1122 VAL 1122 1122 ?   ?   ?   A . n 
C 2 1123 SER 1123 1123 ?   ?   ?   A . n 
C 2 1124 GLY 1124 1124 ?   ?   ?   A . n 
C 2 1125 ASN 1125 1125 ?   ?   ?   A . n 
C 2 1126 CYS 1126 1126 ?   ?   ?   A . n 
C 2 1127 ASP 1127 1127 ?   ?   ?   A . n 
C 2 1128 VAL 1128 1128 ?   ?   ?   A . n 
C 2 1129 VAL 1129 1129 ?   ?   ?   A . n 
C 2 1130 ILE 1130 1130 ?   ?   ?   A . n 
C 2 1131 GLY 1131 1131 ?   ?   ?   A . n 
C 2 1132 ILE 1132 1132 ?   ?   ?   A . n 
C 2 1133 VAL 1133 1133 ?   ?   ?   A . n 
C 2 1134 ASN 1134 1134 ?   ?   ?   A . n 
C 2 1135 ASN 1135 1135 ?   ?   ?   A . n 
C 2 1136 THR 1136 1136 ?   ?   ?   A . n 
C 2 1137 VAL 1137 1137 ?   ?   ?   A . n 
C 2 1138 TYR 1138 1138 ?   ?   ?   A . n 
C 2 1139 ASP 1139 1139 ?   ?   ?   A . n 
C 2 1140 PRO 1140 1140 ?   ?   ?   A . n 
C 2 1141 LEU 1141 1141 ?   ?   ?   A . n 
C 2 1142 GLN 1142 1142 ?   ?   ?   A . n 
C 2 1143 PRO 1143 1143 ?   ?   ?   A . n 
C 2 1144 GLU 1144 1144 ?   ?   ?   A . n 
C 2 1145 LEU 1145 1145 ?   ?   ?   A . n 
C 2 1146 ASP 1146 1146 ?   ?   ?   A . n 
C 2 1147 SER 1147 1147 ?   ?   ?   A . n 
C 2 1148 PHE 1148 1148 ?   ?   ?   A . n 
C 2 1149 LYS 1149 1149 ?   ?   ?   A . n 
C 2 1150 GLU 1150 1150 ?   ?   ?   A . n 
C 2 1151 GLU 1151 1151 ?   ?   ?   A . n 
C 2 1152 LEU 1152 1152 ?   ?   ?   A . n 
C 2 1153 ASP 1153 1153 ?   ?   ?   A . n 
C 2 1154 LYS 1154 1154 ?   ?   ?   A . n 
C 2 1155 TYR 1155 1155 ?   ?   ?   A . n 
C 2 1156 PHE 1156 1156 ?   ?   ?   A . n 
C 2 1157 LYS 1157 1157 ?   ?   ?   A . n 
C 2 1158 ASN 1158 1158 ?   ?   ?   A . n 
C 2 1159 HIS 1159 1159 ?   ?   ?   A . n 
C 2 1160 THR 1160 1160 ?   ?   ?   A . n 
C 2 1161 SER 1161 1161 ?   ?   ?   A . n 
C 2 1162 PRO 1162 1162 ?   ?   ?   A . n 
C 2 1163 ASP 1163 1163 ?   ?   ?   A . n 
C 2 1164 VAL 1164 1164 ?   ?   ?   A . n 
C 2 1165 ASP 1165 1165 ?   ?   ?   A . n 
C 2 1166 LEU 1166 1166 ?   ?   ?   A . n 
C 2 1167 GLY 1167 1167 ?   ?   ?   A . n 
C 2 1168 ASP 1168 1168 ?   ?   ?   A . n 
C 2 1169 ILE 1169 1169 ?   ?   ?   A . n 
C 2 1170 SER 1170 1170 ?   ?   ?   A . n 
C 2 1171 GLY 1171 1171 ?   ?   ?   A . n 
C 2 1172 ILE 1172 1172 ?   ?   ?   A . n 
C 2 1173 ASN 1173 1173 ?   ?   ?   A . n 
C 2 1174 ALA 1174 1174 ?   ?   ?   A . n 
C 2 1175 SER 1175 1175 ?   ?   ?   A . n 
C 2 1176 VAL 1176 1176 ?   ?   ?   A . n 
C 2 1177 VAL 1177 1177 ?   ?   ?   A . n 
C 2 1178 ASN 1178 1178 ?   ?   ?   A . n 
C 2 1179 ILE 1179 1179 ?   ?   ?   A . n 
C 2 1180 GLN 1180 1180 ?   ?   ?   A . n 
C 2 1181 LYS 1181 1181 ?   ?   ?   A . n 
C 2 1182 GLU 1182 1182 ?   ?   ?   A . n 
C 2 1183 ILE 1183 1183 ?   ?   ?   A . n 
C 2 1184 ASP 1184 1184 ?   ?   ?   A . n 
C 2 1185 ARG 1185 1185 ?   ?   ?   A . n 
C 2 1186 LEU 1186 1186 ?   ?   ?   A . n 
C 2 1187 ASN 1187 1187 ?   ?   ?   A . n 
C 2 1188 GLU 1188 1188 ?   ?   ?   A . n 
C 2 1189 VAL 1189 1189 ?   ?   ?   A . n 
C 2 1190 ALA 1190 1190 ?   ?   ?   A . n 
C 2 1191 LYS 1191 1191 ?   ?   ?   A . n 
C 2 1192 ASN 1192 1192 ?   ?   ?   A . n 
C 2 1193 LEU 1193 1193 ?   ?   ?   A . n 
C 2 1194 ASN 1194 1194 ?   ?   ?   A . n 
C 2 1195 GLU 1195 1195 ?   ?   ?   A . n 
C 2 1196 SER 1196 1196 ?   ?   ?   A . n 
C 2 1197 LEU 1197 1197 ?   ?   ?   A . n 
C 2 1198 ILE 1198 1198 ?   ?   ?   A . n 
C 2 1199 ASP 1199 1199 ?   ?   ?   A . n 
C 2 1200 LEU 1200 1200 ?   ?   ?   A . n 
C 2 1201 GLN 1201 1201 ?   ?   ?   A . n 
C 2 1202 GLU 1202 1202 ?   ?   ?   A . n 
C 2 1203 LEU 1203 1203 ?   ?   ?   A . n 
C 2 1204 GLY 1204 1204 ?   ?   ?   A . n 
C 2 1205 LYS 1205 1205 ?   ?   ?   A . n 
C 2 1206 TYR 1206 1206 ?   ?   ?   A . n 
C 2 1207 GLU 1207 1207 ?   ?   ?   A . n 
C 2 1208 GLN 1208 1208 ?   ?   ?   A . n 
C 2 1209 GLY 1209 1209 ?   ?   ?   A . n 
C 2 1210 SER 1210 1210 ?   ?   ?   A . n 
C 2 1211 GLY 1211 1211 ?   ?   ?   A . n 
C 2 1212 TYR 1212 1212 ?   ?   ?   A . n 
C 2 1213 ILE 1213 1213 ?   ?   ?   A . n 
C 2 1214 PRO 1214 1214 ?   ?   ?   A . n 
C 2 1215 GLU 1215 1215 ?   ?   ?   A . n 
C 2 1216 ALA 1216 1216 ?   ?   ?   A . n 
C 2 1217 PRO 1217 1217 ?   ?   ?   A . n 
C 2 1218 ARG 1218 1218 ?   ?   ?   A . n 
C 2 1219 ASP 1219 1219 ?   ?   ?   A . n 
C 2 1220 GLY 1220 1220 ?   ?   ?   A . n 
C 2 1221 GLN 1221 1221 ?   ?   ?   A . n 
C 2 1222 ALA 1222 1222 ?   ?   ?   A . n 
C 2 1223 TYR 1223 1223 ?   ?   ?   A . n 
C 2 1224 VAL 1224 1224 ?   ?   ?   A . n 
C 2 1225 ARG 1225 1225 ?   ?   ?   A . n 
C 2 1226 LYS 1226 1226 ?   ?   ?   A . n 
C 2 1227 ASP 1227 1227 ?   ?   ?   A . n 
C 2 1228 GLY 1228 1228 ?   ?   ?   A . n 
C 2 1229 GLU 1229 1229 ?   ?   ?   A . n 
C 2 1230 TRP 1230 1230 ?   ?   ?   A . n 
C 2 1231 VAL 1231 1231 ?   ?   ?   A . n 
C 2 1232 PHE 1232 1232 ?   ?   ?   A . n 
C 2 1233 LEU 1233 1233 ?   ?   ?   A . n 
C 2 1234 SER 1234 1234 ?   ?   ?   A . n 
C 2 1235 THR 1235 1235 ?   ?   ?   A . n 
C 2 1236 PHE 1236 1236 ?   ?   ?   A . n 
C 2 1237 LEU 1237 1237 ?   ?   ?   A . n 
C 2 1238 SER 1238 1238 ?   ?   ?   A . n 
C 2 1239 GLY 1239 1239 ?   ?   ?   A . n 
C 2 1240 LEU 1240 1240 ?   ?   ?   A . n 
C 2 1241 GLU 1241 1241 ?   ?   ?   A . n 
C 2 1242 VAL 1242 1242 ?   ?   ?   A . n 
C 2 1243 LEU 1243 1243 ?   ?   ?   A . n 
C 2 1244 PHE 1244 1244 ?   ?   ?   A . n 
C 2 1245 GLN 1245 1245 ?   ?   ?   A . n 
C 2 1246 GLY 1246 1246 ?   ?   ?   A . n 
C 2 1247 PRO 1247 1247 ?   ?   ?   A . n 
C 2 1248 GLY 1248 1248 ?   ?   ?   A . n 
C 2 1249 GLY 1249 1249 ?   ?   ?   A . n 
C 2 1250 TRP 1250 1250 ?   ?   ?   A . n 
C 2 1251 SER 1251 1251 ?   ?   ?   A . n 
C 2 1252 HIS 1252 1252 ?   ?   ?   A . n 
C 2 1253 PRO 1253 1253 ?   ?   ?   A . n 
C 2 1254 GLN 1254 1254 ?   ?   ?   A . n 
C 2 1255 PHE 1255 1255 ?   ?   ?   A . n 
C 2 1256 GLU 1256 1256 ?   ?   ?   A . n 
C 2 1257 LYS 1257 1257 ?   ?   ?   A . n 
C 2 1258 GLY 1258 1258 ?   ?   ?   A . n 
C 2 1259 GLY 1259 1259 ?   ?   ?   A . n 
C 2 1260 GLY 1260 1260 ?   ?   ?   A . n 
C 2 1261 SER 1261 1261 ?   ?   ?   A . n 
C 2 1262 GLY 1262 1262 ?   ?   ?   A . n 
C 2 1263 GLY 1263 1263 ?   ?   ?   A . n 
C 2 1264 GLY 1264 1264 ?   ?   ?   A . n 
C 2 1265 SER 1265 1265 ?   ?   ?   A . n 
C 2 1266 GLY 1266 1266 ?   ?   ?   A . n 
C 2 1267 GLY 1267 1267 ?   ?   ?   A . n 
C 2 1268 SER 1268 1268 ?   ?   ?   A . n 
C 2 1269 ALA 1269 1269 ?   ?   ?   A . n 
C 2 1270 TRP 1270 1270 ?   ?   ?   A . n 
C 2 1271 SER 1271 1271 ?   ?   ?   A . n 
C 2 1272 HIS 1272 1272 ?   ?   ?   A . n 
C 2 1273 PRO 1273 1273 ?   ?   ?   A . n 
C 2 1274 GLN 1274 1274 ?   ?   ?   A . n 
C 2 1275 PHE 1275 1275 ?   ?   ?   A . n 
C 2 1276 GLU 1276 1276 ?   ?   ?   A . n 
C 2 1277 LYS 1277 1277 ?   ?   ?   A . n 
C 2 1278 GLY 1278 1278 ?   ?   ?   A . n 
C 2 1279 GLY 1279 1279 ?   ?   ?   A . n 
C 2 1280 SER 1280 1280 ?   ?   ?   A . n 
C 2 1281 HIS 1281 1281 ?   ?   ?   A . n 
C 2 1282 HIS 1282 1282 ?   ?   ?   A . n 
C 2 1283 HIS 1283 1283 ?   ?   ?   A . n 
C 2 1284 HIS 1284 1284 ?   ?   ?   A . n 
C 2 1285 HIS 1285 1285 ?   ?   ?   A . n 
C 2 1286 HIS 1286 1286 ?   ?   ?   A . n 
C 2 1287 HIS 1287 1287 ?   ?   ?   A . n 
C 2 1288 HIS 1288 1288 ?   ?   ?   A . n 
# 
loop_
_pdbx_branch_scheme.asym_id 
_pdbx_branch_scheme.entity_id 
_pdbx_branch_scheme.mon_id 
_pdbx_branch_scheme.num 
_pdbx_branch_scheme.pdb_asym_id 
_pdbx_branch_scheme.pdb_mon_id 
_pdbx_branch_scheme.pdb_seq_num 
_pdbx_branch_scheme.auth_asym_id 
_pdbx_branch_scheme.auth_mon_id 
_pdbx_branch_scheme.auth_seq_num 
_pdbx_branch_scheme.hetero 
D 3 NAG 1 B NAG 1 D NAG 616 n 
D 3 NAG 2 B NAG 2 D NAG 617 n 
E 3 NAG 1 E NAG 1 D NAG 621 n 
E 3 NAG 2 E NAG 2 D NAG 622 n 
F 3 NAG 1 F NAG 1 C NAG 294 n 
F 3 NAG 2 F NAG 2 C NAG 295 n 
G 3 NAG 1 G NAG 1 C NAG 298 n 
G 3 NAG 2 G NAG 2 C NAG 299 n 
H 3 NAG 1 H NAG 1 C NAG 300 n 
H 3 NAG 2 H NAG 2 C NAG 301 n 
I 3 NAG 1 I NAG 1 C NAG 304 n 
I 3 NAG 2 I NAG 2 C NAG 305 n 
J 3 NAG 1 J NAG 1 A NAG 595 n 
J 3 NAG 2 J NAG 2 A NAG 596 n 
K 4 NAG 1 K NAG 1 A NAG 597 n 
K 4 NAG 2 K NAG 2 A NAG 598 n 
K 4 BMA 3 K BMA 3 A BMA 599 n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
L 5 NAG 1 701  614 NAG NAG D . 
M 5 NAG 1 702  618 NAG NAG D . 
N 5 NAG 1 703  619 NAG NAG D . 
O 5 NAG 1 704  620 NAG NAG D . 
P 5 NAG 1 1301 293 NAG NAG C . 
Q 5 NAG 1 1302 302 NAG NAG C . 
R 5 NAG 1 1303 303 NAG NAG C . 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8Z7B 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8Z7B 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8Z7B 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.entry_id                                 8Z7B 
_refine.pdbx_diffrn_id                           ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             ? 
_refine.ls_d_res_high                            . 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.B_iso_mean                               ? 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_ksol                 ? 
_refine.solvent_model_param_bsol                 ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.details                                  ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.001  ? 9837  ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.376  ? 13375 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 21.275 ? 3570  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.039  ? 1497  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.003  ? 1698  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     8Z7B 
_struct.title                        
;Cryo-EM structure of SARS-CoV-2 S trimer in the early fusion intermediate conformation (E-FIC) (focused refinement of NTD-SD1-RBD-ACE2)
;
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8Z7B 
_struct_keywords.text            'Spike-ACE2 complex, VIRAL PROTEIN' 
_struct_keywords.pdbx_keywords   'VIRAL PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 2 ? 
D N N 3 ? 
E N N 3 ? 
F N N 3 ? 
G N N 3 ? 
H N N 3 ? 
I N N 3 ? 
J N N 3 ? 
K N N 4 ? 
L N N 5 ? 
M N N 5 ? 
N N N 5 ? 
O N N 5 ? 
P N N 5 ? 
Q N N 5 ? 
R N N 5 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP ACE2_HUMAN  Q9BYF1 ? 1 
;MSSSSWLLLSLVAVTAAQSTIEEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLA
QMYPLQEIQNLTVKLQLQALQQNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNE
RLWAWESWRSEVGKQLRPLYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHL
HAYVRAKLMNAYPSYISPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGL
PNMTQGFWENSMLTDPGNVQKAVCHPTAWDLGKGDFRILMCTKVTMDDFLTAHHEMGHIQYDMAYAAQPFLLRNGANEGF
HEAVGEIMSLSAATPKHLKSIGLLSPDFQEDNETEINFLLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEM
KREIVGVVEPVPHDETYCDPASLFHVSNDYSFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISNSTEAGQKLFNMLRL
GKSEPWTLALENVVGAKNMNVRPLLNYFEPLFTWLKDQNKNSFVGWSTDWSPYAD
;
1 
2 UNP SPIKE_SARS2 P0DTC2 ? 2 
;MFVFLVLLPLVSSQCVNLTTRTQLPPAYTNSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAIHVSGTNGTKRFD
NPVLPFNDGVYFASTEKSNIIRGWIFGTTLDSKTQSLLIVNNATNVVIKVCEFQFCNDPFLGVYYHKNNKSWMESEFRVY
SSANNCTFEYVSQPFLMDLEGKQGNFKNLREFVFKNIDGYFKIYSKHTPINLVRDLPQGFSALEPLVDLPIGINITRFQT
LLALHRSYLTPGDSSSGWTAGAAAYYVGYLQPRTFLLKYNENGTITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNFRV
QPTESIVRFPNITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSF
VIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPC
NGVEGFNCYFPLQSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCGPKKSTNLVKNKCVNFNFNGLTGTGVLTESNKKFL
PFQQFGRDIADTTDAVRDPQTLEILDITPCSFGGVSVITPGTNTSNQVAVLYQDVNCTEVPVAIHADQLTPTWRVYSTGS
NVFQTRAGCLIGAEHVNNSYECDIPIGAGICASYQTQTNSPRRARSVASQSIIAYTMSLGAENSVAYSNNSIAIPTNFTI
SVTTEILPVSMTKTSVDCTMYICGDSTECSNLLLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKDFGGF
NFSQILPDPSKPSKRSFIEDLLFNKVTLADAGFIKQYGDCLGDIAARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAG
TITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALN
TLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRV
DFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDGKAHFPREGVFVSNGTHWFVTQRNFYEPQIITTDNT
FVSGNCDVVIGIVNNTVYDPLQPELDSFKEELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDL
QELGKYEQ
;
1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8Z7B D 1 ? 615  ? Q9BYF1 1 ? 615  ? 1 615  
2 2 8Z7B C 1 ? 1208 ? P0DTC2 1 ? 1208 ? 1 1208 
3 2 8Z7B A 1 ? 1208 ? P0DTC2 1 ? 1208 ? 1 1208 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8Z7B LEU D 616  ? UNP Q9BYF1 ?   ?   'expression tag' 616  1   
1 8Z7B GLU D 617  ? UNP Q9BYF1 ?   ?   'expression tag' 617  2   
1 8Z7B VAL D 618  ? UNP Q9BYF1 ?   ?   'expression tag' 618  3   
1 8Z7B LEU D 619  ? UNP Q9BYF1 ?   ?   'expression tag' 619  4   
1 8Z7B PHE D 620  ? UNP Q9BYF1 ?   ?   'expression tag' 620  5   
1 8Z7B GLN D 621  ? UNP Q9BYF1 ?   ?   'expression tag' 621  6   
1 8Z7B GLY D 622  ? UNP Q9BYF1 ?   ?   'expression tag' 622  7   
1 8Z7B PRO D 623  ? UNP Q9BYF1 ?   ?   'expression tag' 623  8   
1 8Z7B HIS D 624  ? UNP Q9BYF1 ?   ?   'expression tag' 624  9   
1 8Z7B HIS D 625  ? UNP Q9BYF1 ?   ?   'expression tag' 625  10  
1 8Z7B HIS D 626  ? UNP Q9BYF1 ?   ?   'expression tag' 626  11  
1 8Z7B HIS D 627  ? UNP Q9BYF1 ?   ?   'expression tag' 627  12  
1 8Z7B HIS D 628  ? UNP Q9BYF1 ?   ?   'expression tag' 628  13  
1 8Z7B HIS D 629  ? UNP Q9BYF1 ?   ?   'expression tag' 629  14  
1 8Z7B HIS D 630  ? UNP Q9BYF1 ?   ?   'expression tag' 630  15  
1 8Z7B HIS D 631  ? UNP Q9BYF1 ?   ?   'expression tag' 631  16  
2 8Z7B GLY C 614  ? UNP P0DTC2 ASP 614 variant          614  17  
2 8Z7B GLY C 1209 ? UNP P0DTC2 ?   ?   'expression tag' 1209 18  
2 8Z7B SER C 1210 ? UNP P0DTC2 ?   ?   'expression tag' 1210 19  
2 8Z7B GLY C 1211 ? UNP P0DTC2 ?   ?   'expression tag' 1211 20  
2 8Z7B TYR C 1212 ? UNP P0DTC2 ?   ?   'expression tag' 1212 21  
2 8Z7B ILE C 1213 ? UNP P0DTC2 ?   ?   'expression tag' 1213 22  
2 8Z7B PRO C 1214 ? UNP P0DTC2 ?   ?   'expression tag' 1214 23  
2 8Z7B GLU C 1215 ? UNP P0DTC2 ?   ?   'expression tag' 1215 24  
2 8Z7B ALA C 1216 ? UNP P0DTC2 ?   ?   'expression tag' 1216 25  
2 8Z7B PRO C 1217 ? UNP P0DTC2 ?   ?   'expression tag' 1217 26  
2 8Z7B ARG C 1218 ? UNP P0DTC2 ?   ?   'expression tag' 1218 27  
2 8Z7B ASP C 1219 ? UNP P0DTC2 ?   ?   'expression tag' 1219 28  
2 8Z7B GLY C 1220 ? UNP P0DTC2 ?   ?   'expression tag' 1220 29  
2 8Z7B GLN C 1221 ? UNP P0DTC2 ?   ?   'expression tag' 1221 30  
2 8Z7B ALA C 1222 ? UNP P0DTC2 ?   ?   'expression tag' 1222 31  
2 8Z7B TYR C 1223 ? UNP P0DTC2 ?   ?   'expression tag' 1223 32  
2 8Z7B VAL C 1224 ? UNP P0DTC2 ?   ?   'expression tag' 1224 33  
2 8Z7B ARG C 1225 ? UNP P0DTC2 ?   ?   'expression tag' 1225 34  
2 8Z7B LYS C 1226 ? UNP P0DTC2 ?   ?   'expression tag' 1226 35  
2 8Z7B ASP C 1227 ? UNP P0DTC2 ?   ?   'expression tag' 1227 36  
2 8Z7B GLY C 1228 ? UNP P0DTC2 ?   ?   'expression tag' 1228 37  
2 8Z7B GLU C 1229 ? UNP P0DTC2 ?   ?   'expression tag' 1229 38  
2 8Z7B TRP C 1230 ? UNP P0DTC2 ?   ?   'expression tag' 1230 39  
2 8Z7B VAL C 1231 ? UNP P0DTC2 ?   ?   'expression tag' 1231 40  
2 8Z7B PHE C 1232 ? UNP P0DTC2 ?   ?   'expression tag' 1232 41  
2 8Z7B LEU C 1233 ? UNP P0DTC2 ?   ?   'expression tag' 1233 42  
2 8Z7B SER C 1234 ? UNP P0DTC2 ?   ?   'expression tag' 1234 43  
2 8Z7B THR C 1235 ? UNP P0DTC2 ?   ?   'expression tag' 1235 44  
2 8Z7B PHE C 1236 ? UNP P0DTC2 ?   ?   'expression tag' 1236 45  
2 8Z7B LEU C 1237 ? UNP P0DTC2 ?   ?   'expression tag' 1237 46  
2 8Z7B SER C 1238 ? UNP P0DTC2 ?   ?   'expression tag' 1238 47  
2 8Z7B GLY C 1239 ? UNP P0DTC2 ?   ?   'expression tag' 1239 48  
2 8Z7B LEU C 1240 ? UNP P0DTC2 ?   ?   'expression tag' 1240 49  
2 8Z7B GLU C 1241 ? UNP P0DTC2 ?   ?   'expression tag' 1241 50  
2 8Z7B VAL C 1242 ? UNP P0DTC2 ?   ?   'expression tag' 1242 51  
2 8Z7B LEU C 1243 ? UNP P0DTC2 ?   ?   'expression tag' 1243 52  
2 8Z7B PHE C 1244 ? UNP P0DTC2 ?   ?   'expression tag' 1244 53  
2 8Z7B GLN C 1245 ? UNP P0DTC2 ?   ?   'expression tag' 1245 54  
2 8Z7B GLY C 1246 ? UNP P0DTC2 ?   ?   'expression tag' 1246 55  
2 8Z7B PRO C 1247 ? UNP P0DTC2 ?   ?   'expression tag' 1247 56  
2 8Z7B GLY C 1248 ? UNP P0DTC2 ?   ?   'expression tag' 1248 57  
2 8Z7B GLY C 1249 ? UNP P0DTC2 ?   ?   'expression tag' 1249 58  
2 8Z7B TRP C 1250 ? UNP P0DTC2 ?   ?   'expression tag' 1250 59  
2 8Z7B SER C 1251 ? UNP P0DTC2 ?   ?   'expression tag' 1251 60  
2 8Z7B HIS C 1252 ? UNP P0DTC2 ?   ?   'expression tag' 1252 61  
2 8Z7B PRO C 1253 ? UNP P0DTC2 ?   ?   'expression tag' 1253 62  
2 8Z7B GLN C 1254 ? UNP P0DTC2 ?   ?   'expression tag' 1254 63  
2 8Z7B PHE C 1255 ? UNP P0DTC2 ?   ?   'expression tag' 1255 64  
2 8Z7B GLU C 1256 ? UNP P0DTC2 ?   ?   'expression tag' 1256 65  
2 8Z7B LYS C 1257 ? UNP P0DTC2 ?   ?   'expression tag' 1257 66  
2 8Z7B GLY C 1258 ? UNP P0DTC2 ?   ?   'expression tag' 1258 67  
2 8Z7B GLY C 1259 ? UNP P0DTC2 ?   ?   'expression tag' 1259 68  
2 8Z7B GLY C 1260 ? UNP P0DTC2 ?   ?   'expression tag' 1260 69  
2 8Z7B SER C 1261 ? UNP P0DTC2 ?   ?   'expression tag' 1261 70  
2 8Z7B GLY C 1262 ? UNP P0DTC2 ?   ?   'expression tag' 1262 71  
2 8Z7B GLY C 1263 ? UNP P0DTC2 ?   ?   'expression tag' 1263 72  
2 8Z7B GLY C 1264 ? UNP P0DTC2 ?   ?   'expression tag' 1264 73  
2 8Z7B SER C 1265 ? UNP P0DTC2 ?   ?   'expression tag' 1265 74  
2 8Z7B GLY C 1266 ? UNP P0DTC2 ?   ?   'expression tag' 1266 75  
2 8Z7B GLY C 1267 ? UNP P0DTC2 ?   ?   'expression tag' 1267 76  
2 8Z7B SER C 1268 ? UNP P0DTC2 ?   ?   'expression tag' 1268 77  
2 8Z7B ALA C 1269 ? UNP P0DTC2 ?   ?   'expression tag' 1269 78  
2 8Z7B TRP C 1270 ? UNP P0DTC2 ?   ?   'expression tag' 1270 79  
2 8Z7B SER C 1271 ? UNP P0DTC2 ?   ?   'expression tag' 1271 80  
2 8Z7B HIS C 1272 ? UNP P0DTC2 ?   ?   'expression tag' 1272 81  
2 8Z7B PRO C 1273 ? UNP P0DTC2 ?   ?   'expression tag' 1273 82  
2 8Z7B GLN C 1274 ? UNP P0DTC2 ?   ?   'expression tag' 1274 83  
2 8Z7B PHE C 1275 ? UNP P0DTC2 ?   ?   'expression tag' 1275 84  
2 8Z7B GLU C 1276 ? UNP P0DTC2 ?   ?   'expression tag' 1276 85  
2 8Z7B LYS C 1277 ? UNP P0DTC2 ?   ?   'expression tag' 1277 86  
2 8Z7B GLY C 1278 ? UNP P0DTC2 ?   ?   'expression tag' 1278 87  
2 8Z7B GLY C 1279 ? UNP P0DTC2 ?   ?   'expression tag' 1279 88  
2 8Z7B SER C 1280 ? UNP P0DTC2 ?   ?   'expression tag' 1280 89  
2 8Z7B HIS C 1281 ? UNP P0DTC2 ?   ?   'expression tag' 1281 90  
2 8Z7B HIS C 1282 ? UNP P0DTC2 ?   ?   'expression tag' 1282 91  
2 8Z7B HIS C 1283 ? UNP P0DTC2 ?   ?   'expression tag' 1283 92  
2 8Z7B HIS C 1284 ? UNP P0DTC2 ?   ?   'expression tag' 1284 93  
2 8Z7B HIS C 1285 ? UNP P0DTC2 ?   ?   'expression tag' 1285 94  
2 8Z7B HIS C 1286 ? UNP P0DTC2 ?   ?   'expression tag' 1286 95  
2 8Z7B HIS C 1287 ? UNP P0DTC2 ?   ?   'expression tag' 1287 96  
2 8Z7B HIS C 1288 ? UNP P0DTC2 ?   ?   'expression tag' 1288 97  
3 8Z7B GLY A 614  ? UNP P0DTC2 ASP 614 variant          614  98  
3 8Z7B GLY A 1209 ? UNP P0DTC2 ?   ?   'expression tag' 1209 99  
3 8Z7B SER A 1210 ? UNP P0DTC2 ?   ?   'expression tag' 1210 100 
3 8Z7B GLY A 1211 ? UNP P0DTC2 ?   ?   'expression tag' 1211 101 
3 8Z7B TYR A 1212 ? UNP P0DTC2 ?   ?   'expression tag' 1212 102 
3 8Z7B ILE A 1213 ? UNP P0DTC2 ?   ?   'expression tag' 1213 103 
3 8Z7B PRO A 1214 ? UNP P0DTC2 ?   ?   'expression tag' 1214 104 
3 8Z7B GLU A 1215 ? UNP P0DTC2 ?   ?   'expression tag' 1215 105 
3 8Z7B ALA A 1216 ? UNP P0DTC2 ?   ?   'expression tag' 1216 106 
3 8Z7B PRO A 1217 ? UNP P0DTC2 ?   ?   'expression tag' 1217 107 
3 8Z7B ARG A 1218 ? UNP P0DTC2 ?   ?   'expression tag' 1218 108 
3 8Z7B ASP A 1219 ? UNP P0DTC2 ?   ?   'expression tag' 1219 109 
3 8Z7B GLY A 1220 ? UNP P0DTC2 ?   ?   'expression tag' 1220 110 
3 8Z7B GLN A 1221 ? UNP P0DTC2 ?   ?   'expression tag' 1221 111 
3 8Z7B ALA A 1222 ? UNP P0DTC2 ?   ?   'expression tag' 1222 112 
3 8Z7B TYR A 1223 ? UNP P0DTC2 ?   ?   'expression tag' 1223 113 
3 8Z7B VAL A 1224 ? UNP P0DTC2 ?   ?   'expression tag' 1224 114 
3 8Z7B ARG A 1225 ? UNP P0DTC2 ?   ?   'expression tag' 1225 115 
3 8Z7B LYS A 1226 ? UNP P0DTC2 ?   ?   'expression tag' 1226 116 
3 8Z7B ASP A 1227 ? UNP P0DTC2 ?   ?   'expression tag' 1227 117 
3 8Z7B GLY A 1228 ? UNP P0DTC2 ?   ?   'expression tag' 1228 118 
3 8Z7B GLU A 1229 ? UNP P0DTC2 ?   ?   'expression tag' 1229 119 
3 8Z7B TRP A 1230 ? UNP P0DTC2 ?   ?   'expression tag' 1230 120 
3 8Z7B VAL A 1231 ? UNP P0DTC2 ?   ?   'expression tag' 1231 121 
3 8Z7B PHE A 1232 ? UNP P0DTC2 ?   ?   'expression tag' 1232 122 
3 8Z7B LEU A 1233 ? UNP P0DTC2 ?   ?   'expression tag' 1233 123 
3 8Z7B SER A 1234 ? UNP P0DTC2 ?   ?   'expression tag' 1234 124 
3 8Z7B THR A 1235 ? UNP P0DTC2 ?   ?   'expression tag' 1235 125 
3 8Z7B PHE A 1236 ? UNP P0DTC2 ?   ?   'expression tag' 1236 126 
3 8Z7B LEU A 1237 ? UNP P0DTC2 ?   ?   'expression tag' 1237 127 
3 8Z7B SER A 1238 ? UNP P0DTC2 ?   ?   'expression tag' 1238 128 
3 8Z7B GLY A 1239 ? UNP P0DTC2 ?   ?   'expression tag' 1239 129 
3 8Z7B LEU A 1240 ? UNP P0DTC2 ?   ?   'expression tag' 1240 130 
3 8Z7B GLU A 1241 ? UNP P0DTC2 ?   ?   'expression tag' 1241 131 
3 8Z7B VAL A 1242 ? UNP P0DTC2 ?   ?   'expression tag' 1242 132 
3 8Z7B LEU A 1243 ? UNP P0DTC2 ?   ?   'expression tag' 1243 133 
3 8Z7B PHE A 1244 ? UNP P0DTC2 ?   ?   'expression tag' 1244 134 
3 8Z7B GLN A 1245 ? UNP P0DTC2 ?   ?   'expression tag' 1245 135 
3 8Z7B GLY A 1246 ? UNP P0DTC2 ?   ?   'expression tag' 1246 136 
3 8Z7B PRO A 1247 ? UNP P0DTC2 ?   ?   'expression tag' 1247 137 
3 8Z7B GLY A 1248 ? UNP P0DTC2 ?   ?   'expression tag' 1248 138 
3 8Z7B GLY A 1249 ? UNP P0DTC2 ?   ?   'expression tag' 1249 139 
3 8Z7B TRP A 1250 ? UNP P0DTC2 ?   ?   'expression tag' 1250 140 
3 8Z7B SER A 1251 ? UNP P0DTC2 ?   ?   'expression tag' 1251 141 
3 8Z7B HIS A 1252 ? UNP P0DTC2 ?   ?   'expression tag' 1252 142 
3 8Z7B PRO A 1253 ? UNP P0DTC2 ?   ?   'expression tag' 1253 143 
3 8Z7B GLN A 1254 ? UNP P0DTC2 ?   ?   'expression tag' 1254 144 
3 8Z7B PHE A 1255 ? UNP P0DTC2 ?   ?   'expression tag' 1255 145 
3 8Z7B GLU A 1256 ? UNP P0DTC2 ?   ?   'expression tag' 1256 146 
3 8Z7B LYS A 1257 ? UNP P0DTC2 ?   ?   'expression tag' 1257 147 
3 8Z7B GLY A 1258 ? UNP P0DTC2 ?   ?   'expression tag' 1258 148 
3 8Z7B GLY A 1259 ? UNP P0DTC2 ?   ?   'expression tag' 1259 149 
3 8Z7B GLY A 1260 ? UNP P0DTC2 ?   ?   'expression tag' 1260 150 
3 8Z7B SER A 1261 ? UNP P0DTC2 ?   ?   'expression tag' 1261 151 
3 8Z7B GLY A 1262 ? UNP P0DTC2 ?   ?   'expression tag' 1262 152 
3 8Z7B GLY A 1263 ? UNP P0DTC2 ?   ?   'expression tag' 1263 153 
3 8Z7B GLY A 1264 ? UNP P0DTC2 ?   ?   'expression tag' 1264 154 
3 8Z7B SER A 1265 ? UNP P0DTC2 ?   ?   'expression tag' 1265 155 
3 8Z7B GLY A 1266 ? UNP P0DTC2 ?   ?   'expression tag' 1266 156 
3 8Z7B GLY A 1267 ? UNP P0DTC2 ?   ?   'expression tag' 1267 157 
3 8Z7B SER A 1268 ? UNP P0DTC2 ?   ?   'expression tag' 1268 158 
3 8Z7B ALA A 1269 ? UNP P0DTC2 ?   ?   'expression tag' 1269 159 
3 8Z7B TRP A 1270 ? UNP P0DTC2 ?   ?   'expression tag' 1270 160 
3 8Z7B SER A 1271 ? UNP P0DTC2 ?   ?   'expression tag' 1271 161 
3 8Z7B HIS A 1272 ? UNP P0DTC2 ?   ?   'expression tag' 1272 162 
3 8Z7B PRO A 1273 ? UNP P0DTC2 ?   ?   'expression tag' 1273 163 
3 8Z7B GLN A 1274 ? UNP P0DTC2 ?   ?   'expression tag' 1274 164 
3 8Z7B PHE A 1275 ? UNP P0DTC2 ?   ?   'expression tag' 1275 165 
3 8Z7B GLU A 1276 ? UNP P0DTC2 ?   ?   'expression tag' 1276 166 
3 8Z7B LYS A 1277 ? UNP P0DTC2 ?   ?   'expression tag' 1277 167 
3 8Z7B GLY A 1278 ? UNP P0DTC2 ?   ?   'expression tag' 1278 168 
3 8Z7B GLY A 1279 ? UNP P0DTC2 ?   ?   'expression tag' 1279 169 
3 8Z7B SER A 1280 ? UNP P0DTC2 ?   ?   'expression tag' 1280 170 
3 8Z7B HIS A 1281 ? UNP P0DTC2 ?   ?   'expression tag' 1281 171 
3 8Z7B HIS A 1282 ? UNP P0DTC2 ?   ?   'expression tag' 1282 172 
3 8Z7B HIS A 1283 ? UNP P0DTC2 ?   ?   'expression tag' 1283 173 
3 8Z7B HIS A 1284 ? UNP P0DTC2 ?   ?   'expression tag' 1284 174 
3 8Z7B HIS A 1285 ? UNP P0DTC2 ?   ?   'expression tag' 1285 175 
3 8Z7B HIS A 1286 ? UNP P0DTC2 ?   ?   'expression tag' 1286 176 
3 8Z7B HIS A 1287 ? UNP P0DTC2 ?   ?   'expression tag' 1287 177 
3 8Z7B HIS A 1288 ? UNP P0DTC2 ?   ?   'expression tag' 1288 178 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   trimeric 
_pdbx_struct_assembly.oligomeric_count     3 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 THR A 20  ? ASN A 53  ? THR D 20  ASN D 53  1 ? 34 
HELX_P HELX_P2  AA2 THR A 55  ? GLN A 81  ? THR D 55  GLN D 81  1 ? 27 
HELX_P HELX_P3  AA3 ASN A 90  ? GLN A 101 ? ASN D 90  GLN D 101 1 ? 12 
HELX_P HELX_P4  AA4 SER A 109 ? THR A 129 ? SER D 109 THR D 129 1 ? 21 
HELX_P HELX_P5  AA5 LEU A 144 ? SER A 155 ? LEU D 144 SER D 155 1 ? 12 
HELX_P HELX_P6  AA6 ASP A 157 ? VAL A 172 ? ASP D 157 VAL D 172 1 ? 16 
HELX_P HELX_P7  AA7 LEU A 176 ? ASN A 194 ? LEU D 176 ASN D 194 1 ? 19 
HELX_P HELX_P8  AA8 ASP A 198 ? GLY A 205 ? ASP D 198 GLY D 205 1 ? 8  
HELX_P HELX_P9  AA9 ASP A 206 ? GLU A 208 ? ASP D 206 GLU D 208 5 ? 3  
HELX_P HELX_P10 AB1 ARG A 219 ? TYR A 252 ? ARG D 219 TYR D 252 1 ? 34 
HELX_P HELX_P11 AB2 TRP A 275 ? TYR A 279 ? TRP D 275 TYR D 279 5 ? 5  
HELX_P HELX_P12 AB3 VAL A 293 ? GLN A 300 ? VAL D 293 GLN D 300 1 ? 8  
HELX_P HELX_P13 AB4 ASP A 303 ? GLY A 319 ? ASP D 303 GLY D 319 1 ? 17 
HELX_P HELX_P14 AB5 THR A 324 ? SER A 331 ? THR D 324 SER D 331 1 ? 8  
HELX_P HELX_P15 AB6 THR A 365 ? ALA A 386 ? THR D 365 ALA D 386 1 ? 22 
HELX_P HELX_P16 AB7 ALA A 387 ? GLN A 388 ? ALA D 387 GLN D 388 5 ? 2  
HELX_P HELX_P17 AB8 PRO A 389 ? ARG A 393 ? PRO D 389 ARG D 393 5 ? 5  
HELX_P HELX_P18 AB9 GLY A 399 ? ALA A 413 ? GLY D 399 ALA D 413 1 ? 15 
HELX_P HELX_P19 AC1 THR A 414 ? GLY A 422 ? THR D 414 GLY D 422 1 ? 9  
HELX_P HELX_P20 AC2 ASP A 431 ? VAL A 447 ? ASP D 431 VAL D 447 1 ? 17 
HELX_P HELX_P21 AC3 GLY A 448 ? GLY A 466 ? GLY D 448 GLY D 466 1 ? 19 
HELX_P HELX_P22 AC4 PRO A 469 ? ASP A 471 ? PRO D 469 ASP D 471 5 ? 3  
HELX_P HELX_P23 AC5 GLN A 472 ? ILE A 484 ? GLN D 472 ILE D 484 1 ? 13 
HELX_P HELX_P24 AC6 ASP A 499 ? SER A 502 ? ASP D 499 SER D 502 5 ? 4  
HELX_P HELX_P25 AC7 LEU A 503 ? ASN A 508 ? LEU D 503 ASN D 508 1 ? 6  
HELX_P HELX_P26 AC8 PHE A 512 ? ALA A 533 ? PHE D 512 ALA D 533 1 ? 22 
HELX_P HELX_P27 AC9 SER A 547 ? ARG A 559 ? SER D 547 ARG D 559 1 ? 13 
HELX_P HELX_P28 AD1 PRO A 565 ? VAL A 574 ? PRO D 565 VAL D 574 1 ? 10 
HELX_P HELX_P29 AD2 VAL A 581 ? PHE A 588 ? VAL D 581 PHE D 588 1 ? 8  
HELX_P HELX_P30 AD3 PHE A 588 ? ASN A 599 ? PHE D 588 ASN D 599 1 ? 12 
HELX_P HELX_P31 AD4 PRO C 337 ? ASN C 343 ? PRO A 337 ASN A 343 1 ? 7  
HELX_P HELX_P32 AD5 TYR C 365 ? ASN C 370 ? TYR A 365 ASN A 370 1 ? 6  
HELX_P HELX_P33 AD6 PRO C 384 ? LEU C 390 ? PRO A 384 LEU A 390 5 ? 7  
HELX_P HELX_P34 AD7 ASP C 405 ? VAL C 407 ? ASP A 405 VAL A 407 5 ? 3  
HELX_P HELX_P35 AD8 LYS C 417 ? ASN C 422 ? LYS A 417 ASN A 422 1 ? 6  
HELX_P HELX_P36 AD9 SER C 438 ? SER C 443 ? SER A 438 SER A 443 1 ? 6  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1  disulf ?    ? A CYS 133 SG  ? ? ? 1_555 A CYS 141 SG ? ? D CYS 133 D CYS 141  1_555 ? ? ? ? ? ? ? 2.032 ? ?               
disulf2  disulf ?    ? A CYS 344 SG  ? ? ? 1_555 A CYS 361 SG ? ? D CYS 344 D CYS 361  1_555 ? ? ? ? ? ? ? 2.031 ? ?               
disulf3  disulf ?    ? A CYS 530 SG  ? ? ? 1_555 A CYS 542 SG ? ? D CYS 530 D CYS 542  1_555 ? ? ? ? ? ? ? 2.030 ? ?               
disulf4  disulf ?    ? B CYS 15  SG  ? ? ? 1_555 B CYS 136 SG ? ? C CYS 15  C CYS 136  1_555 ? ? ? ? ? ? ? 2.029 ? ?               
disulf5  disulf ?    ? B CYS 131 SG  ? ? ? 1_555 B CYS 166 SG ? ? C CYS 131 C CYS 166  1_555 ? ? ? ? ? ? ? 2.031 ? ?               
disulf6  disulf ?    ? C CYS 336 SG  ? ? ? 1_555 C CYS 361 SG ? ? A CYS 336 A CYS 361  1_555 ? ? ? ? ? ? ? 2.031 ? ?               
disulf7  disulf ?    ? C CYS 379 SG  ? ? ? 1_555 C CYS 432 SG ? ? A CYS 379 A CYS 432  1_555 ? ? ? ? ? ? ? 2.033 ? ?               
disulf8  disulf ?    ? C CYS 391 SG  ? ? ? 1_555 C CYS 525 SG ? ? A CYS 391 A CYS 525  1_555 ? ? ? ? ? ? ? 2.032 ? ?               
disulf9  disulf ?    ? C CYS 480 SG  ? ? ? 1_555 C CYS 488 SG ? ? A CYS 480 A CYS 488  1_555 ? ? ? ? ? ? ? 2.030 ? ?               
disulf10 disulf ?    ? C CYS 538 SG  ? ? ? 1_555 C CYS 590 SG ? ? A CYS 538 A CYS 590  1_555 ? ? ? ? ? ? ? 2.032 ? ?               
covale1  covale one  ? A ASN 53  ND2 ? ? ? 1_555 L NAG .   C1 ? ? D ASN 53  D NAG 701  1_555 ? ? ? ? ? ? ? 1.439 ? N-Glycosylation 
covale2  covale one  ? A ASN 90  ND2 ? ? ? 1_555 D NAG .   C1 ? ? D ASN 90  B NAG 1    1_555 ? ? ? ? ? ? ? 1.441 ? N-Glycosylation 
covale3  covale one  ? A ASN 103 ND2 ? ? ? 1_555 M NAG .   C1 ? ? D ASN 103 D NAG 702  1_555 ? ? ? ? ? ? ? 1.441 ? N-Glycosylation 
covale4  covale one  ? A ASN 322 ND2 ? ? ? 1_555 N NAG .   C1 ? ? D ASN 322 D NAG 703  1_555 ? ? ? ? ? ? ? 1.440 ? N-Glycosylation 
covale5  covale one  ? A ASN 432 ND2 ? ? ? 1_555 O NAG .   C1 ? ? D ASN 432 D NAG 704  1_555 ? ? ? ? ? ? ? 1.440 ? N-Glycosylation 
covale6  covale one  ? A ASN 546 ND2 ? ? ? 1_555 E NAG .   C1 ? ? D ASN 546 E NAG 1    1_555 ? ? ? ? ? ? ? 1.440 ? N-Glycosylation 
covale7  covale one  ? B ASN 17  ND2 ? ? ? 1_555 F NAG .   C1 ? ? C ASN 17  F NAG 1    1_555 ? ? ? ? ? ? ? 1.442 ? N-Glycosylation 
covale8  covale one  ? B ASN 61  ND2 ? ? ? 1_555 I NAG .   C1 ? ? C ASN 61  I NAG 1    1_555 ? ? ? ? ? ? ? 1.445 ? N-Glycosylation 
covale9  covale one  ? B ASN 122 ND2 ? ? ? 1_555 G NAG .   C1 ? ? C ASN 122 G NAG 1    1_555 ? ? ? ? ? ? ? 1.440 ? N-Glycosylation 
covale10 covale one  ? B ASN 149 ND2 ? ? ? 1_555 H NAG .   C1 ? ? C ASN 149 H NAG 1    1_555 ? ? ? ? ? ? ? 1.440 ? N-Glycosylation 
covale11 covale one  ? B ASN 165 ND2 ? ? ? 1_555 Q NAG .   C1 ? ? C ASN 165 C NAG 1302 1_555 ? ? ? ? ? ? ? 1.441 ? N-Glycosylation 
covale12 covale one  ? B ASN 234 ND2 ? ? ? 1_555 P NAG .   C1 ? ? C ASN 234 C NAG 1301 1_555 ? ? ? ? ? ? ? 1.440 ? N-Glycosylation 
covale13 covale one  ? B ASN 282 ND2 ? ? ? 1_555 R NAG .   C1 ? ? C ASN 282 C NAG 1303 1_555 ? ? ? ? ? ? ? 1.440 ? N-Glycosylation 
covale14 covale one  ? C ASN 331 ND2 ? ? ? 1_555 K NAG .   C1 ? ? A ASN 331 K NAG 1    1_555 ? ? ? ? ? ? ? 1.441 ? N-Glycosylation 
covale15 covale one  ? C ASN 343 ND2 ? ? ? 1_555 J NAG .   C1 ? ? A ASN 343 J NAG 1    1_555 ? ? ? ? ? ? ? 1.441 ? N-Glycosylation 
covale16 covale both ? D NAG .   O4  ? ? ? 1_555 D NAG .   C1 ? ? B NAG 1   B NAG 2    1_555 ? ? ? ? ? ? ? 1.441 ? ?               
covale17 covale both ? E NAG .   O4  ? ? ? 1_555 E NAG .   C1 ? ? E NAG 1   E NAG 2    1_555 ? ? ? ? ? ? ? 1.441 ? ?               
covale18 covale both ? F NAG .   O4  ? ? ? 1_555 F NAG .   C1 ? ? F NAG 1   F NAG 2    1_555 ? ? ? ? ? ? ? 1.442 ? ?               
covale19 covale both ? G NAG .   O4  ? ? ? 1_555 G NAG .   C1 ? ? G NAG 1   G NAG 2    1_555 ? ? ? ? ? ? ? 1.443 ? ?               
covale20 covale both ? H NAG .   O4  ? ? ? 1_555 H NAG .   C1 ? ? H NAG 1   H NAG 2    1_555 ? ? ? ? ? ? ? 1.443 ? ?               
covale21 covale both ? I NAG .   O4  ? ? ? 1_555 I NAG .   C1 ? ? I NAG 1   I NAG 2    1_555 ? ? ? ? ? ? ? 1.441 ? ?               
covale22 covale both ? J NAG .   O4  ? ? ? 1_555 J NAG .   C1 ? ? J NAG 1   J NAG 2    1_555 ? ? ? ? ? ? ? 1.441 ? ?               
covale23 covale both ? K NAG .   O4  ? ? ? 1_555 K NAG .   C1 ? ? K NAG 1   K NAG 2    1_555 ? ? ? ? ? ? ? 1.442 ? ?               
covale24 covale both ? K NAG .   O4  ? ? ? 1_555 K BMA .   C1 ? ? K NAG 2   K BMA 3    1_555 ? ? ? ? ? ? ? 1.445 ? ?               
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
disulf ? ? 
covale ? ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1  NAG D .   ? ASN A 90  ? NAG B 1    ? 1_555 ASN D 90  ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
2  NAG E .   ? ASN A 546 ? NAG E 1    ? 1_555 ASN D 546 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
3  NAG F .   ? ASN B 17  ? NAG F 1    ? 1_555 ASN C 17  ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
4  NAG G .   ? ASN B 122 ? NAG G 1    ? 1_555 ASN C 122 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
5  NAG H .   ? ASN B 149 ? NAG H 1    ? 1_555 ASN C 149 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
6  NAG I .   ? ASN B 61  ? NAG I 1    ? 1_555 ASN C 61  ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
7  NAG J .   ? ASN C 343 ? NAG J 1    ? 1_555 ASN A 343 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
8  NAG K .   ? ASN C 331 ? NAG K 1    ? 1_555 ASN A 331 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
9  NAG L .   ? ASN A 53  ? NAG D 701  ? 1_555 ASN D 53  ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
10 NAG M .   ? ASN A 103 ? NAG D 702  ? 1_555 ASN D 103 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
11 NAG N .   ? ASN A 322 ? NAG D 703  ? 1_555 ASN D 322 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
12 NAG O .   ? ASN A 432 ? NAG D 704  ? 1_555 ASN D 432 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
13 NAG P .   ? ASN B 234 ? NAG C 1301 ? 1_555 ASN C 234 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
14 NAG Q .   ? ASN B 165 ? NAG C 1302 ? 1_555 ASN C 165 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
15 NAG R .   ? ASN B 282 ? NAG C 1303 ? 1_555 ASN C 282 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
16 CYS A 133 ? CYS A 141 ? CYS D 133  ? 1_555 CYS D 141 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
17 CYS A 344 ? CYS A 361 ? CYS D 344  ? 1_555 CYS D 361 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
18 CYS A 530 ? CYS A 542 ? CYS D 530  ? 1_555 CYS D 542 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
19 CYS B 15  ? CYS B 136 ? CYS C 15   ? 1_555 CYS C 136 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
20 CYS B 131 ? CYS B 166 ? CYS C 131  ? 1_555 CYS C 166 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
21 CYS C 336 ? CYS C 361 ? CYS A 336  ? 1_555 CYS A 361 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
22 CYS C 379 ? CYS C 432 ? CYS A 379  ? 1_555 CYS A 432 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
23 CYS C 391 ? CYS C 525 ? CYS A 391  ? 1_555 CYS A 525 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
24 CYS C 480 ? CYS C 488 ? CYS A 480  ? 1_555 CYS A 488 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
25 CYS C 538 ? CYS C 590 ? CYS A 538  ? 1_555 CYS A 590 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 2 ? 
AA2 ? 2 ? 
AA3 ? 2 ? 
AA4 ? 3 ? 
AA5 ? 7 ? 
AA6 ? 7 ? 
AA7 ? 3 ? 
AA8 ? 4 ? 
AA9 ? 6 ? 
AB1 ? 5 ? 
AB2 ? 2 ? 
AB3 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA2 1 2 ? parallel      
AA3 1 2 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA5 4 5 ? anti-parallel 
AA5 5 6 ? anti-parallel 
AA5 6 7 ? anti-parallel 
AA6 1 2 ? parallel      
AA6 2 3 ? anti-parallel 
AA6 3 4 ? anti-parallel 
AA6 4 5 ? anti-parallel 
AA6 5 6 ? anti-parallel 
AA6 6 7 ? parallel      
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA8 2 3 ? parallel      
AA8 3 4 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AA9 4 5 ? anti-parallel 
AA9 5 6 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB1 2 3 ? anti-parallel 
AB1 3 4 ? anti-parallel 
AB1 4 5 ? anti-parallel 
AB2 1 2 ? anti-parallel 
AB3 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 LYS A 131 ? CYS A 133 ? LYS D 131 CYS D 133 
AA1 2 CYS A 141 ? LEU A 143 ? CYS D 141 LEU D 143 
AA2 1 LEU A 262 ? PRO A 263 ? LEU D 262 PRO D 263 
AA2 2 VAL A 487 ? VAL A 488 ? VAL D 487 VAL D 488 
AA3 1 THR A 347 ? ASP A 350 ? THR D 347 ASP D 350 
AA3 2 PHE A 356 ? LEU A 359 ? PHE D 356 LEU D 359 
AA4 1 ALA B 27  ? ASN B 30  ? ALA C 27  ASN C 30  
AA4 2 ASN B 61  ? ILE B 68  ? ASN C 61  ILE C 68  
AA4 3 ARG B 78  ? PHE B 79  ? ARG C 78  PHE C 79  
AA5 1 ALA B 27  ? ASN B 30  ? ALA C 27  ASN C 30  
AA5 2 ASN B 61  ? ILE B 68  ? ASN C 61  ILE C 68  
AA5 3 ALA B 263 ? TYR B 269 ? ALA C 263 TYR C 269 
AA5 4 VAL B 90  ? GLU B 96  ? VAL C 90  GLU C 96  
AA5 5 ASN B 188 ? ILE B 197 ? ASN C 188 ILE C 197 
AA5 6 TYR B 200 ? HIS B 207 ? TYR C 200 HIS C 207 
AA5 7 GLU B 224 ? PRO B 230 ? GLU C 224 PRO C 230 
AA6 1 VAL B 42  ? PHE B 43  ? VAL C 42  PHE C 43  
AA6 2 PHE C 565 ? ARG C 567 ? PHE A 565 ARG A 567 
AA6 3 THR C 573 ? ARG C 577 ? THR A 573 ARG A 577 
AA6 4 ILE C 584 ? THR C 588 ? ILE A 584 THR A 588 
AA6 5 THR C 547 ? GLU C 554 ? THR A 547 GLU A 554 
AA6 6 CYS C 538 ? ASN C 542 ? CYS A 538 ASN A 542 
AA6 7 GLU C 324 ? SER C 325 ? GLU A 324 SER A 325 
AA7 1 LEU B 48  ? PHE B 55  ? LEU C 48  PHE C 55  
AA7 2 GLN B 271 ? TYR B 279 ? GLN C 271 TYR C 279 
AA7 3 ILE B 285 ? ASP B 290 ? ILE C 285 ASP C 290 
AA8 1 VAL B 83  ? PRO B 85  ? VAL C 83  PRO C 85  
AA8 2 ARG B 237 ? ARG B 246 ? ARG C 237 ARG C 246 
AA8 3 PHE B 135 ? TYR B 144 ? PHE C 135 TYR C 144 
AA8 4 SER B 155 ? TYR B 160 ? SER C 155 TYR C 160 
AA9 1 VAL B 83  ? PRO B 85  ? VAL C 83  PRO C 85  
AA9 2 ARG B 237 ? ARG B 246 ? ARG C 237 ARG C 246 
AA9 3 GLY B 103 ? GLY B 107 ? GLY C 103 GLY C 107 
AA9 4 SER B 116 ? ASN B 121 ? SER C 116 ASN C 121 
AA9 5 VAL B 126 ? CYS B 131 ? VAL C 126 CYS C 131 
AA9 6 PHE B 168 ? TYR B 170 ? PHE C 168 TYR C 170 
AB1 1 ASN C 354 ? ILE C 358 ? ASN A 354 ILE A 358 
AB1 2 ASN C 394 ? ARG C 403 ? ASN A 394 ARG A 403 
AB1 3 PRO C 507 ? GLU C 516 ? PRO A 507 GLU A 516 
AB1 4 GLY C 431 ? ASN C 437 ? GLY A 431 ASN A 437 
AB1 5 THR C 376 ? TYR C 380 ? THR A 376 TYR A 380 
AB2 1 LEU C 452 ? ARG C 454 ? LEU A 452 ARG A 454 
AB2 2 LEU C 492 ? SER C 494 ? LEU A 492 SER A 494 
AB3 1 TYR C 473 ? GLN C 474 ? TYR A 473 GLN A 474 
AB3 2 CYS C 488 ? TYR C 489 ? CYS A 488 TYR A 489 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N VAL A 132 ? N VAL D 132 O LEU A 142 ? O LEU D 142 
AA2 1 2 N LEU A 262 ? N LEU D 262 O VAL A 488 ? O VAL D 488 
AA3 1 2 N TRP A 349 ? N TRP D 349 O ARG A 357 ? O ARG D 357 
AA4 1 2 N ALA B 27  ? N ALA C 27  O TRP B 64  ? O TRP C 64  
AA4 2 3 N ILE B 68  ? N ILE C 68  O ARG B 78  ? O ARG C 78  
AA5 1 2 N ALA B 27  ? N ALA C 27  O TRP B 64  ? O TRP C 64  
AA5 2 3 N ALA B 67  ? N ALA C 67  O ALA B 263 ? O ALA C 263 
AA5 3 4 O GLY B 268 ? O GLY C 268 N TYR B 91  ? N TYR C 91  
AA5 4 5 N PHE B 92  ? N PHE C 92  O PHE B 192 ? O PHE C 192 
AA5 5 6 N LYS B 195 ? N LYS C 195 O LYS B 202 ? O LYS C 202 
AA5 6 7 N PHE B 201 ? N PHE C 201 O LEU B 229 ? O LEU C 229 
AA6 1 2 N PHE B 43  ? N PHE C 43  O ARG C 567 ? O ARG A 567 
AA6 2 3 N GLY C 566 ? N GLY A 566 O ALA C 575 ? O ALA A 575 
AA6 3 4 N ASP C 574 ? N ASP A 574 O ILE C 587 ? O ILE A 587 
AA6 4 5 O ASP C 586 ? O ASP A 586 N THR C 553 ? N THR A 553 
AA6 5 6 O GLY C 550 ? O GLY A 550 N VAL C 539 ? N VAL A 539 
AA6 6 7 O ASN C 540 ? O ASN A 540 N GLU C 324 ? N GLU A 324 
AA7 1 2 N PHE B 55  ? N PHE C 55  O GLN B 271 ? O GLN C 271 
AA7 2 3 N LYS B 278 ? N LYS C 278 O THR B 286 ? O THR C 286 
AA8 1 2 N LEU B 84  ? N LEU C 84  O PHE B 238 ? O PHE C 238 
AA8 2 3 O LEU B 244 ? O LEU C 244 N VAL B 143 ? N VAL C 143 
AA8 3 4 N PHE B 140 ? N PHE C 140 O ARG B 158 ? O ARG C 158 
AA9 1 2 N LEU B 84  ? N LEU C 84  O PHE B 238 ? O PHE C 238 
AA9 2 3 O LEU B 241 ? O LEU C 241 N GLY B 103 ? N GLY C 103 
AA9 3 4 N PHE B 106 ? N PHE C 106 O LEU B 117 ? O LEU C 117 
AA9 4 5 N LEU B 118 ? N LEU C 118 O LYS B 129 ? O LYS C 129 
AA9 5 6 N ILE B 128 ? N ILE C 128 O TYR B 170 ? O TYR C 170 
AB1 1 2 N ILE C 358 ? N ILE A 358 O VAL C 395 ? O VAL A 395 
AB1 2 3 N ILE C 402 ? N ILE A 402 O TYR C 508 ? O TYR A 508 
AB1 3 4 O VAL C 511 ? O VAL A 511 N ILE C 434 ? N ILE A 434 
AB1 4 5 O GLY C 431 ? O GLY A 431 N TYR C 380 ? N TYR A 380 
AB2 1 2 N TYR C 453 ? N TYR A 453 O GLN C 493 ? O GLN A 493 
AB3 1 2 N TYR C 473 ? N TYR A 473 O TYR C 489 ? O TYR A 489 
# 
_pdbx_entry_details.entry_id                   8Z7B 
_pdbx_entry_details.has_ligand_of_interest     N 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 LYS D 353 ? ? -95.67  58.88  
2  1 THR C 33  ? ? -64.81  1.30   
3  1 LYS C 41  ? ? -99.49  34.31  
4  1 ASN C 122 ? ? -99.71  36.40  
5  1 ALA C 123 ? ? 68.99   -2.42  
6  1 TRP C 152 ? ? -93.10  -60.16 
7  1 VAL C 159 ? ? -125.09 -56.68 
8  1 LEU C 216 ? ? -39.04  136.79 
9  1 LEU C 249 ? ? -90.82  53.11  
10 1 ASN A 343 ? ? -99.89  33.09  
11 1 TYR A 449 ? ? -98.58  33.03  
12 1 PHE A 543 ? ? -93.89  -64.82 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8Z7B 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    8Z7B 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.30 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               179746 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            8.0 
# 
loop_
_em_entity_assembly.id 
_em_entity_assembly.parent_id 
_em_entity_assembly.source 
_em_entity_assembly.type 
_em_entity_assembly.name 
_em_entity_assembly.details 
_em_entity_assembly.synonym 
_em_entity_assembly.oligomeric_details 
_em_entity_assembly.entity_id_list 
1 0 RECOMBINANT COMPLEX 'SARS-CoV-2 S trimer in the early fusion intermediate conformation (E-FIC) (focused on NTD-SD1-RBD-ACE2)' 
? ? ? 1,2 
2 1 RECOMBINANT COMPLEX 'D614G spike protein'                                                                                     
? ? ? 2   
3 1 RECOMBINANT COMPLEX 'Human ACE2'                                                                                              
? ? ? 1   
# 
_em_imaging.entry_id                        8Z7B 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             1000 
_em_imaging.nominal_defocus_max             3000 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              8Z7B 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                8Z7B 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
_em_single_particle_entity.entry_id              8Z7B 
_em_single_particle_entity.id                    1 
_em_single_particle_entity.image_processing_id   1 
_em_single_particle_entity.point_symmetry        C1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1    1 Y 1 D MET 1    ? A MET 1    
2    1 Y 1 D SER 2    ? A SER 2    
3    1 Y 1 D SER 3    ? A SER 3    
4    1 Y 1 D SER 4    ? A SER 4    
5    1 Y 1 D SER 5    ? A SER 5    
6    1 Y 1 D TRP 6    ? A TRP 6    
7    1 Y 1 D LEU 7    ? A LEU 7    
8    1 Y 1 D LEU 8    ? A LEU 8    
9    1 Y 1 D LEU 9    ? A LEU 9    
10   1 Y 1 D SER 10   ? A SER 10   
11   1 Y 1 D LEU 11   ? A LEU 11   
12   1 Y 1 D VAL 12   ? A VAL 12   
13   1 Y 1 D ALA 13   ? A ALA 13   
14   1 Y 1 D VAL 14   ? A VAL 14   
15   1 Y 1 D THR 15   ? A THR 15   
16   1 Y 1 D ALA 16   ? A ALA 16   
17   1 Y 1 D ALA 17   ? A ALA 17   
18   1 Y 1 D GLN 18   ? A GLN 18   
19   1 Y 1 D ALA 614  ? A ALA 614  
20   1 Y 1 D ASP 615  ? A ASP 615  
21   1 Y 1 D LEU 616  ? A LEU 616  
22   1 Y 1 D GLU 617  ? A GLU 617  
23   1 Y 1 D VAL 618  ? A VAL 618  
24   1 Y 1 D LEU 619  ? A LEU 619  
25   1 Y 1 D PHE 620  ? A PHE 620  
26   1 Y 1 D GLN 621  ? A GLN 621  
27   1 Y 1 D GLY 622  ? A GLY 622  
28   1 Y 1 D PRO 623  ? A PRO 623  
29   1 Y 1 D HIS 624  ? A HIS 624  
30   1 Y 1 D HIS 625  ? A HIS 625  
31   1 Y 1 D HIS 626  ? A HIS 626  
32   1 Y 1 D HIS 627  ? A HIS 627  
33   1 Y 1 D HIS 628  ? A HIS 628  
34   1 Y 1 D HIS 629  ? A HIS 629  
35   1 Y 1 D HIS 630  ? A HIS 630  
36   1 Y 1 D HIS 631  ? A HIS 631  
37   1 Y 1 C MET 1    ? B MET 1    
38   1 Y 1 C PHE 2    ? B PHE 2    
39   1 Y 1 C VAL 3    ? B VAL 3    
40   1 Y 1 C PHE 4    ? B PHE 4    
41   1 Y 1 C LEU 5    ? B LEU 5    
42   1 Y 1 C VAL 6    ? B VAL 6    
43   1 Y 1 C LEU 7    ? B LEU 7    
44   1 Y 1 C LEU 8    ? B LEU 8    
45   1 Y 1 C PRO 9    ? B PRO 9    
46   1 Y 1 C LEU 10   ? B LEU 10   
47   1 Y 1 C VAL 11   ? B VAL 11   
48   1 Y 1 C SER 12   ? B SER 12   
49   1 Y 1 C SER 13   ? B SER 13   
50   1 Y 1 C ASN 74   ? B ASN 74   
51   1 Y 1 C GLY 75   ? B GLY 75   
52   1 Y 1 C LEU 293  ? B LEU 293  
53   1 Y 1 C ASP 294  ? B ASP 294  
54   1 Y 1 C PRO 295  ? B PRO 295  
55   1 Y 1 C LEU 296  ? B LEU 296  
56   1 Y 1 C SER 297  ? B SER 297  
57   1 Y 1 C GLU 298  ? B GLU 298  
58   1 Y 1 C THR 299  ? B THR 299  
59   1 Y 1 C LYS 300  ? B LYS 300  
60   1 Y 1 C CYS 301  ? B CYS 301  
61   1 Y 1 C THR 302  ? B THR 302  
62   1 Y 1 C LEU 303  ? B LEU 303  
63   1 Y 1 C LYS 304  ? B LYS 304  
64   1 Y 1 C SER 305  ? B SER 305  
65   1 Y 1 C PHE 306  ? B PHE 306  
66   1 Y 1 C THR 307  ? B THR 307  
67   1 Y 1 C VAL 308  ? B VAL 308  
68   1 Y 1 C GLU 309  ? B GLU 309  
69   1 Y 1 C LYS 310  ? B LYS 310  
70   1 Y 1 C GLY 311  ? B GLY 311  
71   1 Y 1 C ILE 312  ? B ILE 312  
72   1 Y 1 C TYR 313  ? B TYR 313  
73   1 Y 1 C GLN 314  ? B GLN 314  
74   1 Y 1 C THR 315  ? B THR 315  
75   1 Y 1 C SER 316  ? B SER 316  
76   1 Y 1 C ASN 317  ? B ASN 317  
77   1 Y 1 C PHE 318  ? B PHE 318  
78   1 Y 1 C ARG 319  ? B ARG 319  
79   1 Y 1 C VAL 320  ? B VAL 320  
80   1 Y 1 C GLN 321  ? B GLN 321  
81   1 Y 1 C PRO 322  ? B PRO 322  
82   1 Y 1 C THR 323  ? B THR 323  
83   1 Y 1 C GLU 324  ? B GLU 324  
84   1 Y 1 C SER 325  ? B SER 325  
85   1 Y 1 C ILE 326  ? B ILE 326  
86   1 Y 1 C VAL 327  ? B VAL 327  
87   1 Y 1 C ARG 328  ? B ARG 328  
88   1 Y 1 C PHE 329  ? B PHE 329  
89   1 Y 1 C PRO 330  ? B PRO 330  
90   1 Y 1 C ASN 331  ? B ASN 331  
91   1 Y 1 C ILE 332  ? B ILE 332  
92   1 Y 1 C THR 333  ? B THR 333  
93   1 Y 1 C ASN 334  ? B ASN 334  
94   1 Y 1 C LEU 335  ? B LEU 335  
95   1 Y 1 C CYS 336  ? B CYS 336  
96   1 Y 1 C PRO 337  ? B PRO 337  
97   1 Y 1 C PHE 338  ? B PHE 338  
98   1 Y 1 C GLY 339  ? B GLY 339  
99   1 Y 1 C GLU 340  ? B GLU 340  
100  1 Y 1 C VAL 341  ? B VAL 341  
101  1 Y 1 C PHE 342  ? B PHE 342  
102  1 Y 1 C ASN 343  ? B ASN 343  
103  1 Y 1 C ALA 344  ? B ALA 344  
104  1 Y 1 C THR 345  ? B THR 345  
105  1 Y 1 C ARG 346  ? B ARG 346  
106  1 Y 1 C PHE 347  ? B PHE 347  
107  1 Y 1 C ALA 348  ? B ALA 348  
108  1 Y 1 C SER 349  ? B SER 349  
109  1 Y 1 C VAL 350  ? B VAL 350  
110  1 Y 1 C TYR 351  ? B TYR 351  
111  1 Y 1 C ALA 352  ? B ALA 352  
112  1 Y 1 C TRP 353  ? B TRP 353  
113  1 Y 1 C ASN 354  ? B ASN 354  
114  1 Y 1 C ARG 355  ? B ARG 355  
115  1 Y 1 C LYS 356  ? B LYS 356  
116  1 Y 1 C ARG 357  ? B ARG 357  
117  1 Y 1 C ILE 358  ? B ILE 358  
118  1 Y 1 C SER 359  ? B SER 359  
119  1 Y 1 C ASN 360  ? B ASN 360  
120  1 Y 1 C CYS 361  ? B CYS 361  
121  1 Y 1 C VAL 362  ? B VAL 362  
122  1 Y 1 C ALA 363  ? B ALA 363  
123  1 Y 1 C ASP 364  ? B ASP 364  
124  1 Y 1 C TYR 365  ? B TYR 365  
125  1 Y 1 C SER 366  ? B SER 366  
126  1 Y 1 C VAL 367  ? B VAL 367  
127  1 Y 1 C LEU 368  ? B LEU 368  
128  1 Y 1 C TYR 369  ? B TYR 369  
129  1 Y 1 C ASN 370  ? B ASN 370  
130  1 Y 1 C SER 371  ? B SER 371  
131  1 Y 1 C ALA 372  ? B ALA 372  
132  1 Y 1 C SER 373  ? B SER 373  
133  1 Y 1 C PHE 374  ? B PHE 374  
134  1 Y 1 C SER 375  ? B SER 375  
135  1 Y 1 C THR 376  ? B THR 376  
136  1 Y 1 C PHE 377  ? B PHE 377  
137  1 Y 1 C LYS 378  ? B LYS 378  
138  1 Y 1 C CYS 379  ? B CYS 379  
139  1 Y 1 C TYR 380  ? B TYR 380  
140  1 Y 1 C GLY 381  ? B GLY 381  
141  1 Y 1 C VAL 382  ? B VAL 382  
142  1 Y 1 C SER 383  ? B SER 383  
143  1 Y 1 C PRO 384  ? B PRO 384  
144  1 Y 1 C THR 385  ? B THR 385  
145  1 Y 1 C LYS 386  ? B LYS 386  
146  1 Y 1 C LEU 387  ? B LEU 387  
147  1 Y 1 C ASN 388  ? B ASN 388  
148  1 Y 1 C ASP 389  ? B ASP 389  
149  1 Y 1 C LEU 390  ? B LEU 390  
150  1 Y 1 C CYS 391  ? B CYS 391  
151  1 Y 1 C PHE 392  ? B PHE 392  
152  1 Y 1 C THR 393  ? B THR 393  
153  1 Y 1 C ASN 394  ? B ASN 394  
154  1 Y 1 C VAL 395  ? B VAL 395  
155  1 Y 1 C TYR 396  ? B TYR 396  
156  1 Y 1 C ALA 397  ? B ALA 397  
157  1 Y 1 C ASP 398  ? B ASP 398  
158  1 Y 1 C SER 399  ? B SER 399  
159  1 Y 1 C PHE 400  ? B PHE 400  
160  1 Y 1 C VAL 401  ? B VAL 401  
161  1 Y 1 C ILE 402  ? B ILE 402  
162  1 Y 1 C ARG 403  ? B ARG 403  
163  1 Y 1 C GLY 404  ? B GLY 404  
164  1 Y 1 C ASP 405  ? B ASP 405  
165  1 Y 1 C GLU 406  ? B GLU 406  
166  1 Y 1 C VAL 407  ? B VAL 407  
167  1 Y 1 C ARG 408  ? B ARG 408  
168  1 Y 1 C GLN 409  ? B GLN 409  
169  1 Y 1 C ILE 410  ? B ILE 410  
170  1 Y 1 C ALA 411  ? B ALA 411  
171  1 Y 1 C PRO 412  ? B PRO 412  
172  1 Y 1 C GLY 413  ? B GLY 413  
173  1 Y 1 C GLN 414  ? B GLN 414  
174  1 Y 1 C THR 415  ? B THR 415  
175  1 Y 1 C GLY 416  ? B GLY 416  
176  1 Y 1 C LYS 417  ? B LYS 417  
177  1 Y 1 C ILE 418  ? B ILE 418  
178  1 Y 1 C ALA 419  ? B ALA 419  
179  1 Y 1 C ASP 420  ? B ASP 420  
180  1 Y 1 C TYR 421  ? B TYR 421  
181  1 Y 1 C ASN 422  ? B ASN 422  
182  1 Y 1 C TYR 423  ? B TYR 423  
183  1 Y 1 C LYS 424  ? B LYS 424  
184  1 Y 1 C LEU 425  ? B LEU 425  
185  1 Y 1 C PRO 426  ? B PRO 426  
186  1 Y 1 C ASP 427  ? B ASP 427  
187  1 Y 1 C ASP 428  ? B ASP 428  
188  1 Y 1 C PHE 429  ? B PHE 429  
189  1 Y 1 C THR 430  ? B THR 430  
190  1 Y 1 C GLY 431  ? B GLY 431  
191  1 Y 1 C CYS 432  ? B CYS 432  
192  1 Y 1 C VAL 433  ? B VAL 433  
193  1 Y 1 C ILE 434  ? B ILE 434  
194  1 Y 1 C ALA 435  ? B ALA 435  
195  1 Y 1 C TRP 436  ? B TRP 436  
196  1 Y 1 C ASN 437  ? B ASN 437  
197  1 Y 1 C SER 438  ? B SER 438  
198  1 Y 1 C ASN 439  ? B ASN 439  
199  1 Y 1 C ASN 440  ? B ASN 440  
200  1 Y 1 C LEU 441  ? B LEU 441  
201  1 Y 1 C ASP 442  ? B ASP 442  
202  1 Y 1 C SER 443  ? B SER 443  
203  1 Y 1 C LYS 444  ? B LYS 444  
204  1 Y 1 C VAL 445  ? B VAL 445  
205  1 Y 1 C GLY 446  ? B GLY 446  
206  1 Y 1 C GLY 447  ? B GLY 447  
207  1 Y 1 C ASN 448  ? B ASN 448  
208  1 Y 1 C TYR 449  ? B TYR 449  
209  1 Y 1 C ASN 450  ? B ASN 450  
210  1 Y 1 C TYR 451  ? B TYR 451  
211  1 Y 1 C LEU 452  ? B LEU 452  
212  1 Y 1 C TYR 453  ? B TYR 453  
213  1 Y 1 C ARG 454  ? B ARG 454  
214  1 Y 1 C LEU 455  ? B LEU 455  
215  1 Y 1 C PHE 456  ? B PHE 456  
216  1 Y 1 C ARG 457  ? B ARG 457  
217  1 Y 1 C LYS 458  ? B LYS 458  
218  1 Y 1 C SER 459  ? B SER 459  
219  1 Y 1 C ASN 460  ? B ASN 460  
220  1 Y 1 C LEU 461  ? B LEU 461  
221  1 Y 1 C LYS 462  ? B LYS 462  
222  1 Y 1 C PRO 463  ? B PRO 463  
223  1 Y 1 C PHE 464  ? B PHE 464  
224  1 Y 1 C GLU 465  ? B GLU 465  
225  1 Y 1 C ARG 466  ? B ARG 466  
226  1 Y 1 C ASP 467  ? B ASP 467  
227  1 Y 1 C ILE 468  ? B ILE 468  
228  1 Y 1 C SER 469  ? B SER 469  
229  1 Y 1 C THR 470  ? B THR 470  
230  1 Y 1 C GLU 471  ? B GLU 471  
231  1 Y 1 C ILE 472  ? B ILE 472  
232  1 Y 1 C TYR 473  ? B TYR 473  
233  1 Y 1 C GLN 474  ? B GLN 474  
234  1 Y 1 C ALA 475  ? B ALA 475  
235  1 Y 1 C GLY 476  ? B GLY 476  
236  1 Y 1 C SER 477  ? B SER 477  
237  1 Y 1 C THR 478  ? B THR 478  
238  1 Y 1 C PRO 479  ? B PRO 479  
239  1 Y 1 C CYS 480  ? B CYS 480  
240  1 Y 1 C ASN 481  ? B ASN 481  
241  1 Y 1 C GLY 482  ? B GLY 482  
242  1 Y 1 C VAL 483  ? B VAL 483  
243  1 Y 1 C GLU 484  ? B GLU 484  
244  1 Y 1 C GLY 485  ? B GLY 485  
245  1 Y 1 C PHE 486  ? B PHE 486  
246  1 Y 1 C ASN 487  ? B ASN 487  
247  1 Y 1 C CYS 488  ? B CYS 488  
248  1 Y 1 C TYR 489  ? B TYR 489  
249  1 Y 1 C PHE 490  ? B PHE 490  
250  1 Y 1 C PRO 491  ? B PRO 491  
251  1 Y 1 C LEU 492  ? B LEU 492  
252  1 Y 1 C GLN 493  ? B GLN 493  
253  1 Y 1 C SER 494  ? B SER 494  
254  1 Y 1 C TYR 495  ? B TYR 495  
255  1 Y 1 C GLY 496  ? B GLY 496  
256  1 Y 1 C PHE 497  ? B PHE 497  
257  1 Y 1 C GLN 498  ? B GLN 498  
258  1 Y 1 C PRO 499  ? B PRO 499  
259  1 Y 1 C THR 500  ? B THR 500  
260  1 Y 1 C ASN 501  ? B ASN 501  
261  1 Y 1 C GLY 502  ? B GLY 502  
262  1 Y 1 C VAL 503  ? B VAL 503  
263  1 Y 1 C GLY 504  ? B GLY 504  
264  1 Y 1 C TYR 505  ? B TYR 505  
265  1 Y 1 C GLN 506  ? B GLN 506  
266  1 Y 1 C PRO 507  ? B PRO 507  
267  1 Y 1 C TYR 508  ? B TYR 508  
268  1 Y 1 C ARG 509  ? B ARG 509  
269  1 Y 1 C VAL 510  ? B VAL 510  
270  1 Y 1 C VAL 511  ? B VAL 511  
271  1 Y 1 C VAL 512  ? B VAL 512  
272  1 Y 1 C LEU 513  ? B LEU 513  
273  1 Y 1 C SER 514  ? B SER 514  
274  1 Y 1 C PHE 515  ? B PHE 515  
275  1 Y 1 C GLU 516  ? B GLU 516  
276  1 Y 1 C LEU 517  ? B LEU 517  
277  1 Y 1 C LEU 518  ? B LEU 518  
278  1 Y 1 C HIS 519  ? B HIS 519  
279  1 Y 1 C ALA 520  ? B ALA 520  
280  1 Y 1 C PRO 521  ? B PRO 521  
281  1 Y 1 C ALA 522  ? B ALA 522  
282  1 Y 1 C THR 523  ? B THR 523  
283  1 Y 1 C VAL 524  ? B VAL 524  
284  1 Y 1 C CYS 525  ? B CYS 525  
285  1 Y 1 C GLY 526  ? B GLY 526  
286  1 Y 1 C PRO 527  ? B PRO 527  
287  1 Y 1 C LYS 528  ? B LYS 528  
288  1 Y 1 C LYS 529  ? B LYS 529  
289  1 Y 1 C SER 530  ? B SER 530  
290  1 Y 1 C THR 531  ? B THR 531  
291  1 Y 1 C ASN 532  ? B ASN 532  
292  1 Y 1 C LEU 533  ? B LEU 533  
293  1 Y 1 C VAL 534  ? B VAL 534  
294  1 Y 1 C LYS 535  ? B LYS 535  
295  1 Y 1 C ASN 536  ? B ASN 536  
296  1 Y 1 C LYS 537  ? B LYS 537  
297  1 Y 1 C CYS 538  ? B CYS 538  
298  1 Y 1 C VAL 539  ? B VAL 539  
299  1 Y 1 C ASN 540  ? B ASN 540  
300  1 Y 1 C PHE 541  ? B PHE 541  
301  1 Y 1 C ASN 542  ? B ASN 542  
302  1 Y 1 C PHE 543  ? B PHE 543  
303  1 Y 1 C ASN 544  ? B ASN 544  
304  1 Y 1 C GLY 545  ? B GLY 545  
305  1 Y 1 C LEU 546  ? B LEU 546  
306  1 Y 1 C THR 547  ? B THR 547  
307  1 Y 1 C GLY 548  ? B GLY 548  
308  1 Y 1 C THR 549  ? B THR 549  
309  1 Y 1 C GLY 550  ? B GLY 550  
310  1 Y 1 C VAL 551  ? B VAL 551  
311  1 Y 1 C LEU 552  ? B LEU 552  
312  1 Y 1 C THR 553  ? B THR 553  
313  1 Y 1 C GLU 554  ? B GLU 554  
314  1 Y 1 C SER 555  ? B SER 555  
315  1 Y 1 C ASN 556  ? B ASN 556  
316  1 Y 1 C LYS 557  ? B LYS 557  
317  1 Y 1 C LYS 558  ? B LYS 558  
318  1 Y 1 C PHE 559  ? B PHE 559  
319  1 Y 1 C LEU 560  ? B LEU 560  
320  1 Y 1 C PRO 561  ? B PRO 561  
321  1 Y 1 C PHE 562  ? B PHE 562  
322  1 Y 1 C GLN 563  ? B GLN 563  
323  1 Y 1 C GLN 564  ? B GLN 564  
324  1 Y 1 C PHE 565  ? B PHE 565  
325  1 Y 1 C GLY 566  ? B GLY 566  
326  1 Y 1 C ARG 567  ? B ARG 567  
327  1 Y 1 C ASP 568  ? B ASP 568  
328  1 Y 1 C ILE 569  ? B ILE 569  
329  1 Y 1 C ALA 570  ? B ALA 570  
330  1 Y 1 C ASP 571  ? B ASP 571  
331  1 Y 1 C THR 572  ? B THR 572  
332  1 Y 1 C THR 573  ? B THR 573  
333  1 Y 1 C ASP 574  ? B ASP 574  
334  1 Y 1 C ALA 575  ? B ALA 575  
335  1 Y 1 C VAL 576  ? B VAL 576  
336  1 Y 1 C ARG 577  ? B ARG 577  
337  1 Y 1 C ASP 578  ? B ASP 578  
338  1 Y 1 C PRO 579  ? B PRO 579  
339  1 Y 1 C GLN 580  ? B GLN 580  
340  1 Y 1 C THR 581  ? B THR 581  
341  1 Y 1 C LEU 582  ? B LEU 582  
342  1 Y 1 C GLU 583  ? B GLU 583  
343  1 Y 1 C ILE 584  ? B ILE 584  
344  1 Y 1 C LEU 585  ? B LEU 585  
345  1 Y 1 C ASP 586  ? B ASP 586  
346  1 Y 1 C ILE 587  ? B ILE 587  
347  1 Y 1 C THR 588  ? B THR 588  
348  1 Y 1 C PRO 589  ? B PRO 589  
349  1 Y 1 C CYS 590  ? B CYS 590  
350  1 Y 1 C SER 591  ? B SER 591  
351  1 Y 1 C PHE 592  ? B PHE 592  
352  1 Y 1 C GLY 593  ? B GLY 593  
353  1 Y 1 C GLY 594  ? B GLY 594  
354  1 Y 1 C VAL 595  ? B VAL 595  
355  1 Y 1 C SER 596  ? B SER 596  
356  1 Y 1 C VAL 597  ? B VAL 597  
357  1 Y 1 C ILE 598  ? B ILE 598  
358  1 Y 1 C THR 599  ? B THR 599  
359  1 Y 1 C PRO 600  ? B PRO 600  
360  1 Y 1 C GLY 601  ? B GLY 601  
361  1 Y 1 C THR 602  ? B THR 602  
362  1 Y 1 C ASN 603  ? B ASN 603  
363  1 Y 1 C THR 604  ? B THR 604  
364  1 Y 1 C SER 605  ? B SER 605  
365  1 Y 1 C ASN 606  ? B ASN 606  
366  1 Y 1 C GLN 607  ? B GLN 607  
367  1 Y 1 C VAL 608  ? B VAL 608  
368  1 Y 1 C ALA 609  ? B ALA 609  
369  1 Y 1 C VAL 610  ? B VAL 610  
370  1 Y 1 C LEU 611  ? B LEU 611  
371  1 Y 1 C TYR 612  ? B TYR 612  
372  1 Y 1 C GLN 613  ? B GLN 613  
373  1 Y 1 C GLY 614  ? B GLY 614  
374  1 Y 1 C VAL 615  ? B VAL 615  
375  1 Y 1 C ASN 616  ? B ASN 616  
376  1 Y 1 C CYS 617  ? B CYS 617  
377  1 Y 1 C THR 618  ? B THR 618  
378  1 Y 1 C GLU 619  ? B GLU 619  
379  1 Y 1 C VAL 620  ? B VAL 620  
380  1 Y 1 C PRO 621  ? B PRO 621  
381  1 Y 1 C VAL 622  ? B VAL 622  
382  1 Y 1 C ALA 623  ? B ALA 623  
383  1 Y 1 C ILE 624  ? B ILE 624  
384  1 Y 1 C HIS 625  ? B HIS 625  
385  1 Y 1 C ALA 626  ? B ALA 626  
386  1 Y 1 C ASP 627  ? B ASP 627  
387  1 Y 1 C GLN 628  ? B GLN 628  
388  1 Y 1 C LEU 629  ? B LEU 629  
389  1 Y 1 C THR 630  ? B THR 630  
390  1 Y 1 C PRO 631  ? B PRO 631  
391  1 Y 1 C THR 632  ? B THR 632  
392  1 Y 1 C TRP 633  ? B TRP 633  
393  1 Y 1 C ARG 634  ? B ARG 634  
394  1 Y 1 C VAL 635  ? B VAL 635  
395  1 Y 1 C TYR 636  ? B TYR 636  
396  1 Y 1 C SER 637  ? B SER 637  
397  1 Y 1 C THR 638  ? B THR 638  
398  1 Y 1 C GLY 639  ? B GLY 639  
399  1 Y 1 C SER 640  ? B SER 640  
400  1 Y 1 C ASN 641  ? B ASN 641  
401  1 Y 1 C VAL 642  ? B VAL 642  
402  1 Y 1 C PHE 643  ? B PHE 643  
403  1 Y 1 C GLN 644  ? B GLN 644  
404  1 Y 1 C THR 645  ? B THR 645  
405  1 Y 1 C ARG 646  ? B ARG 646  
406  1 Y 1 C ALA 647  ? B ALA 647  
407  1 Y 1 C GLY 648  ? B GLY 648  
408  1 Y 1 C CYS 649  ? B CYS 649  
409  1 Y 1 C LEU 650  ? B LEU 650  
410  1 Y 1 C ILE 651  ? B ILE 651  
411  1 Y 1 C GLY 652  ? B GLY 652  
412  1 Y 1 C ALA 653  ? B ALA 653  
413  1 Y 1 C GLU 654  ? B GLU 654  
414  1 Y 1 C HIS 655  ? B HIS 655  
415  1 Y 1 C VAL 656  ? B VAL 656  
416  1 Y 1 C ASN 657  ? B ASN 657  
417  1 Y 1 C ASN 658  ? B ASN 658  
418  1 Y 1 C SER 659  ? B SER 659  
419  1 Y 1 C TYR 660  ? B TYR 660  
420  1 Y 1 C GLU 661  ? B GLU 661  
421  1 Y 1 C CYS 662  ? B CYS 662  
422  1 Y 1 C ASP 663  ? B ASP 663  
423  1 Y 1 C ILE 664  ? B ILE 664  
424  1 Y 1 C PRO 665  ? B PRO 665  
425  1 Y 1 C ILE 666  ? B ILE 666  
426  1 Y 1 C GLY 667  ? B GLY 667  
427  1 Y 1 C ALA 668  ? B ALA 668  
428  1 Y 1 C GLY 669  ? B GLY 669  
429  1 Y 1 C ILE 670  ? B ILE 670  
430  1 Y 1 C CYS 671  ? B CYS 671  
431  1 Y 1 C ALA 672  ? B ALA 672  
432  1 Y 1 C SER 673  ? B SER 673  
433  1 Y 1 C TYR 674  ? B TYR 674  
434  1 Y 1 C GLN 675  ? B GLN 675  
435  1 Y 1 C THR 676  ? B THR 676  
436  1 Y 1 C GLN 677  ? B GLN 677  
437  1 Y 1 C THR 678  ? B THR 678  
438  1 Y 1 C ASN 679  ? B ASN 679  
439  1 Y 1 C SER 680  ? B SER 680  
440  1 Y 1 C PRO 681  ? B PRO 681  
441  1 Y 1 C ARG 682  ? B ARG 682  
442  1 Y 1 C ARG 683  ? B ARG 683  
443  1 Y 1 C ALA 684  ? B ALA 684  
444  1 Y 1 C ARG 685  ? B ARG 685  
445  1 Y 1 C SER 686  ? B SER 686  
446  1 Y 1 C VAL 687  ? B VAL 687  
447  1 Y 1 C ALA 688  ? B ALA 688  
448  1 Y 1 C SER 689  ? B SER 689  
449  1 Y 1 C GLN 690  ? B GLN 690  
450  1 Y 1 C SER 691  ? B SER 691  
451  1 Y 1 C ILE 692  ? B ILE 692  
452  1 Y 1 C ILE 693  ? B ILE 693  
453  1 Y 1 C ALA 694  ? B ALA 694  
454  1 Y 1 C TYR 695  ? B TYR 695  
455  1 Y 1 C THR 696  ? B THR 696  
456  1 Y 1 C MET 697  ? B MET 697  
457  1 Y 1 C SER 698  ? B SER 698  
458  1 Y 1 C LEU 699  ? B LEU 699  
459  1 Y 1 C GLY 700  ? B GLY 700  
460  1 Y 1 C ALA 701  ? B ALA 701  
461  1 Y 1 C GLU 702  ? B GLU 702  
462  1 Y 1 C ASN 703  ? B ASN 703  
463  1 Y 1 C SER 704  ? B SER 704  
464  1 Y 1 C VAL 705  ? B VAL 705  
465  1 Y 1 C ALA 706  ? B ALA 706  
466  1 Y 1 C TYR 707  ? B TYR 707  
467  1 Y 1 C SER 708  ? B SER 708  
468  1 Y 1 C ASN 709  ? B ASN 709  
469  1 Y 1 C ASN 710  ? B ASN 710  
470  1 Y 1 C SER 711  ? B SER 711  
471  1 Y 1 C ILE 712  ? B ILE 712  
472  1 Y 1 C ALA 713  ? B ALA 713  
473  1 Y 1 C ILE 714  ? B ILE 714  
474  1 Y 1 C PRO 715  ? B PRO 715  
475  1 Y 1 C THR 716  ? B THR 716  
476  1 Y 1 C ASN 717  ? B ASN 717  
477  1 Y 1 C PHE 718  ? B PHE 718  
478  1 Y 1 C THR 719  ? B THR 719  
479  1 Y 1 C ILE 720  ? B ILE 720  
480  1 Y 1 C SER 721  ? B SER 721  
481  1 Y 1 C VAL 722  ? B VAL 722  
482  1 Y 1 C THR 723  ? B THR 723  
483  1 Y 1 C THR 724  ? B THR 724  
484  1 Y 1 C GLU 725  ? B GLU 725  
485  1 Y 1 C ILE 726  ? B ILE 726  
486  1 Y 1 C LEU 727  ? B LEU 727  
487  1 Y 1 C PRO 728  ? B PRO 728  
488  1 Y 1 C VAL 729  ? B VAL 729  
489  1 Y 1 C SER 730  ? B SER 730  
490  1 Y 1 C MET 731  ? B MET 731  
491  1 Y 1 C THR 732  ? B THR 732  
492  1 Y 1 C LYS 733  ? B LYS 733  
493  1 Y 1 C THR 734  ? B THR 734  
494  1 Y 1 C SER 735  ? B SER 735  
495  1 Y 1 C VAL 736  ? B VAL 736  
496  1 Y 1 C ASP 737  ? B ASP 737  
497  1 Y 1 C CYS 738  ? B CYS 738  
498  1 Y 1 C THR 739  ? B THR 739  
499  1 Y 1 C MET 740  ? B MET 740  
500  1 Y 1 C TYR 741  ? B TYR 741  
501  1 Y 1 C ILE 742  ? B ILE 742  
502  1 Y 1 C CYS 743  ? B CYS 743  
503  1 Y 1 C GLY 744  ? B GLY 744  
504  1 Y 1 C ASP 745  ? B ASP 745  
505  1 Y 1 C SER 746  ? B SER 746  
506  1 Y 1 C THR 747  ? B THR 747  
507  1 Y 1 C GLU 748  ? B GLU 748  
508  1 Y 1 C CYS 749  ? B CYS 749  
509  1 Y 1 C SER 750  ? B SER 750  
510  1 Y 1 C ASN 751  ? B ASN 751  
511  1 Y 1 C LEU 752  ? B LEU 752  
512  1 Y 1 C LEU 753  ? B LEU 753  
513  1 Y 1 C LEU 754  ? B LEU 754  
514  1 Y 1 C GLN 755  ? B GLN 755  
515  1 Y 1 C TYR 756  ? B TYR 756  
516  1 Y 1 C GLY 757  ? B GLY 757  
517  1 Y 1 C SER 758  ? B SER 758  
518  1 Y 1 C PHE 759  ? B PHE 759  
519  1 Y 1 C CYS 760  ? B CYS 760  
520  1 Y 1 C THR 761  ? B THR 761  
521  1 Y 1 C GLN 762  ? B GLN 762  
522  1 Y 1 C LEU 763  ? B LEU 763  
523  1 Y 1 C ASN 764  ? B ASN 764  
524  1 Y 1 C ARG 765  ? B ARG 765  
525  1 Y 1 C ALA 766  ? B ALA 766  
526  1 Y 1 C LEU 767  ? B LEU 767  
527  1 Y 1 C THR 768  ? B THR 768  
528  1 Y 1 C GLY 769  ? B GLY 769  
529  1 Y 1 C ILE 770  ? B ILE 770  
530  1 Y 1 C ALA 771  ? B ALA 771  
531  1 Y 1 C VAL 772  ? B VAL 772  
532  1 Y 1 C GLU 773  ? B GLU 773  
533  1 Y 1 C GLN 774  ? B GLN 774  
534  1 Y 1 C ASP 775  ? B ASP 775  
535  1 Y 1 C LYS 776  ? B LYS 776  
536  1 Y 1 C ASN 777  ? B ASN 777  
537  1 Y 1 C THR 778  ? B THR 778  
538  1 Y 1 C GLN 779  ? B GLN 779  
539  1 Y 1 C GLU 780  ? B GLU 780  
540  1 Y 1 C VAL 781  ? B VAL 781  
541  1 Y 1 C PHE 782  ? B PHE 782  
542  1 Y 1 C ALA 783  ? B ALA 783  
543  1 Y 1 C GLN 784  ? B GLN 784  
544  1 Y 1 C VAL 785  ? B VAL 785  
545  1 Y 1 C LYS 786  ? B LYS 786  
546  1 Y 1 C GLN 787  ? B GLN 787  
547  1 Y 1 C ILE 788  ? B ILE 788  
548  1 Y 1 C TYR 789  ? B TYR 789  
549  1 Y 1 C LYS 790  ? B LYS 790  
550  1 Y 1 C THR 791  ? B THR 791  
551  1 Y 1 C PRO 792  ? B PRO 792  
552  1 Y 1 C PRO 793  ? B PRO 793  
553  1 Y 1 C ILE 794  ? B ILE 794  
554  1 Y 1 C LYS 795  ? B LYS 795  
555  1 Y 1 C ASP 796  ? B ASP 796  
556  1 Y 1 C PHE 797  ? B PHE 797  
557  1 Y 1 C GLY 798  ? B GLY 798  
558  1 Y 1 C GLY 799  ? B GLY 799  
559  1 Y 1 C PHE 800  ? B PHE 800  
560  1 Y 1 C ASN 801  ? B ASN 801  
561  1 Y 1 C PHE 802  ? B PHE 802  
562  1 Y 1 C SER 803  ? B SER 803  
563  1 Y 1 C GLN 804  ? B GLN 804  
564  1 Y 1 C ILE 805  ? B ILE 805  
565  1 Y 1 C LEU 806  ? B LEU 806  
566  1 Y 1 C PRO 807  ? B PRO 807  
567  1 Y 1 C ASP 808  ? B ASP 808  
568  1 Y 1 C PRO 809  ? B PRO 809  
569  1 Y 1 C SER 810  ? B SER 810  
570  1 Y 1 C LYS 811  ? B LYS 811  
571  1 Y 1 C PRO 812  ? B PRO 812  
572  1 Y 1 C SER 813  ? B SER 813  
573  1 Y 1 C LYS 814  ? B LYS 814  
574  1 Y 1 C ARG 815  ? B ARG 815  
575  1 Y 1 C SER 816  ? B SER 816  
576  1 Y 1 C PHE 817  ? B PHE 817  
577  1 Y 1 C ILE 818  ? B ILE 818  
578  1 Y 1 C GLU 819  ? B GLU 819  
579  1 Y 1 C ASP 820  ? B ASP 820  
580  1 Y 1 C LEU 821  ? B LEU 821  
581  1 Y 1 C LEU 822  ? B LEU 822  
582  1 Y 1 C PHE 823  ? B PHE 823  
583  1 Y 1 C ASN 824  ? B ASN 824  
584  1 Y 1 C LYS 825  ? B LYS 825  
585  1 Y 1 C VAL 826  ? B VAL 826  
586  1 Y 1 C THR 827  ? B THR 827  
587  1 Y 1 C LEU 828  ? B LEU 828  
588  1 Y 1 C ALA 829  ? B ALA 829  
589  1 Y 1 C ASP 830  ? B ASP 830  
590  1 Y 1 C ALA 831  ? B ALA 831  
591  1 Y 1 C GLY 832  ? B GLY 832  
592  1 Y 1 C PHE 833  ? B PHE 833  
593  1 Y 1 C ILE 834  ? B ILE 834  
594  1 Y 1 C LYS 835  ? B LYS 835  
595  1 Y 1 C GLN 836  ? B GLN 836  
596  1 Y 1 C TYR 837  ? B TYR 837  
597  1 Y 1 C GLY 838  ? B GLY 838  
598  1 Y 1 C ASP 839  ? B ASP 839  
599  1 Y 1 C CYS 840  ? B CYS 840  
600  1 Y 1 C LEU 841  ? B LEU 841  
601  1 Y 1 C GLY 842  ? B GLY 842  
602  1 Y 1 C ASP 843  ? B ASP 843  
603  1 Y 1 C ILE 844  ? B ILE 844  
604  1 Y 1 C ALA 845  ? B ALA 845  
605  1 Y 1 C ALA 846  ? B ALA 846  
606  1 Y 1 C ARG 847  ? B ARG 847  
607  1 Y 1 C ASP 848  ? B ASP 848  
608  1 Y 1 C LEU 849  ? B LEU 849  
609  1 Y 1 C ILE 850  ? B ILE 850  
610  1 Y 1 C CYS 851  ? B CYS 851  
611  1 Y 1 C ALA 852  ? B ALA 852  
612  1 Y 1 C GLN 853  ? B GLN 853  
613  1 Y 1 C LYS 854  ? B LYS 854  
614  1 Y 1 C PHE 855  ? B PHE 855  
615  1 Y 1 C ASN 856  ? B ASN 856  
616  1 Y 1 C GLY 857  ? B GLY 857  
617  1 Y 1 C LEU 858  ? B LEU 858  
618  1 Y 1 C THR 859  ? B THR 859  
619  1 Y 1 C VAL 860  ? B VAL 860  
620  1 Y 1 C LEU 861  ? B LEU 861  
621  1 Y 1 C PRO 862  ? B PRO 862  
622  1 Y 1 C PRO 863  ? B PRO 863  
623  1 Y 1 C LEU 864  ? B LEU 864  
624  1 Y 1 C LEU 865  ? B LEU 865  
625  1 Y 1 C THR 866  ? B THR 866  
626  1 Y 1 C ASP 867  ? B ASP 867  
627  1 Y 1 C GLU 868  ? B GLU 868  
628  1 Y 1 C MET 869  ? B MET 869  
629  1 Y 1 C ILE 870  ? B ILE 870  
630  1 Y 1 C ALA 871  ? B ALA 871  
631  1 Y 1 C GLN 872  ? B GLN 872  
632  1 Y 1 C TYR 873  ? B TYR 873  
633  1 Y 1 C THR 874  ? B THR 874  
634  1 Y 1 C SER 875  ? B SER 875  
635  1 Y 1 C ALA 876  ? B ALA 876  
636  1 Y 1 C LEU 877  ? B LEU 877  
637  1 Y 1 C LEU 878  ? B LEU 878  
638  1 Y 1 C ALA 879  ? B ALA 879  
639  1 Y 1 C GLY 880  ? B GLY 880  
640  1 Y 1 C THR 881  ? B THR 881  
641  1 Y 1 C ILE 882  ? B ILE 882  
642  1 Y 1 C THR 883  ? B THR 883  
643  1 Y 1 C SER 884  ? B SER 884  
644  1 Y 1 C GLY 885  ? B GLY 885  
645  1 Y 1 C TRP 886  ? B TRP 886  
646  1 Y 1 C THR 887  ? B THR 887  
647  1 Y 1 C PHE 888  ? B PHE 888  
648  1 Y 1 C GLY 889  ? B GLY 889  
649  1 Y 1 C ALA 890  ? B ALA 890  
650  1 Y 1 C GLY 891  ? B GLY 891  
651  1 Y 1 C ALA 892  ? B ALA 892  
652  1 Y 1 C ALA 893  ? B ALA 893  
653  1 Y 1 C LEU 894  ? B LEU 894  
654  1 Y 1 C GLN 895  ? B GLN 895  
655  1 Y 1 C ILE 896  ? B ILE 896  
656  1 Y 1 C PRO 897  ? B PRO 897  
657  1 Y 1 C PHE 898  ? B PHE 898  
658  1 Y 1 C ALA 899  ? B ALA 899  
659  1 Y 1 C MET 900  ? B MET 900  
660  1 Y 1 C GLN 901  ? B GLN 901  
661  1 Y 1 C MET 902  ? B MET 902  
662  1 Y 1 C ALA 903  ? B ALA 903  
663  1 Y 1 C TYR 904  ? B TYR 904  
664  1 Y 1 C ARG 905  ? B ARG 905  
665  1 Y 1 C PHE 906  ? B PHE 906  
666  1 Y 1 C ASN 907  ? B ASN 907  
667  1 Y 1 C GLY 908  ? B GLY 908  
668  1 Y 1 C ILE 909  ? B ILE 909  
669  1 Y 1 C GLY 910  ? B GLY 910  
670  1 Y 1 C VAL 911  ? B VAL 911  
671  1 Y 1 C THR 912  ? B THR 912  
672  1 Y 1 C GLN 913  ? B GLN 913  
673  1 Y 1 C ASN 914  ? B ASN 914  
674  1 Y 1 C VAL 915  ? B VAL 915  
675  1 Y 1 C LEU 916  ? B LEU 916  
676  1 Y 1 C TYR 917  ? B TYR 917  
677  1 Y 1 C GLU 918  ? B GLU 918  
678  1 Y 1 C ASN 919  ? B ASN 919  
679  1 Y 1 C GLN 920  ? B GLN 920  
680  1 Y 1 C LYS 921  ? B LYS 921  
681  1 Y 1 C LEU 922  ? B LEU 922  
682  1 Y 1 C ILE 923  ? B ILE 923  
683  1 Y 1 C ALA 924  ? B ALA 924  
684  1 Y 1 C ASN 925  ? B ASN 925  
685  1 Y 1 C GLN 926  ? B GLN 926  
686  1 Y 1 C PHE 927  ? B PHE 927  
687  1 Y 1 C ASN 928  ? B ASN 928  
688  1 Y 1 C SER 929  ? B SER 929  
689  1 Y 1 C ALA 930  ? B ALA 930  
690  1 Y 1 C ILE 931  ? B ILE 931  
691  1 Y 1 C GLY 932  ? B GLY 932  
692  1 Y 1 C LYS 933  ? B LYS 933  
693  1 Y 1 C ILE 934  ? B ILE 934  
694  1 Y 1 C GLN 935  ? B GLN 935  
695  1 Y 1 C ASP 936  ? B ASP 936  
696  1 Y 1 C SER 937  ? B SER 937  
697  1 Y 1 C LEU 938  ? B LEU 938  
698  1 Y 1 C SER 939  ? B SER 939  
699  1 Y 1 C SER 940  ? B SER 940  
700  1 Y 1 C THR 941  ? B THR 941  
701  1 Y 1 C ALA 942  ? B ALA 942  
702  1 Y 1 C SER 943  ? B SER 943  
703  1 Y 1 C ALA 944  ? B ALA 944  
704  1 Y 1 C LEU 945  ? B LEU 945  
705  1 Y 1 C GLY 946  ? B GLY 946  
706  1 Y 1 C LYS 947  ? B LYS 947  
707  1 Y 1 C LEU 948  ? B LEU 948  
708  1 Y 1 C GLN 949  ? B GLN 949  
709  1 Y 1 C ASP 950  ? B ASP 950  
710  1 Y 1 C VAL 951  ? B VAL 951  
711  1 Y 1 C VAL 952  ? B VAL 952  
712  1 Y 1 C ASN 953  ? B ASN 953  
713  1 Y 1 C GLN 954  ? B GLN 954  
714  1 Y 1 C ASN 955  ? B ASN 955  
715  1 Y 1 C ALA 956  ? B ALA 956  
716  1 Y 1 C GLN 957  ? B GLN 957  
717  1 Y 1 C ALA 958  ? B ALA 958  
718  1 Y 1 C LEU 959  ? B LEU 959  
719  1 Y 1 C ASN 960  ? B ASN 960  
720  1 Y 1 C THR 961  ? B THR 961  
721  1 Y 1 C LEU 962  ? B LEU 962  
722  1 Y 1 C VAL 963  ? B VAL 963  
723  1 Y 1 C LYS 964  ? B LYS 964  
724  1 Y 1 C GLN 965  ? B GLN 965  
725  1 Y 1 C LEU 966  ? B LEU 966  
726  1 Y 1 C SER 967  ? B SER 967  
727  1 Y 1 C SER 968  ? B SER 968  
728  1 Y 1 C ASN 969  ? B ASN 969  
729  1 Y 1 C PHE 970  ? B PHE 970  
730  1 Y 1 C GLY 971  ? B GLY 971  
731  1 Y 1 C ALA 972  ? B ALA 972  
732  1 Y 1 C ILE 973  ? B ILE 973  
733  1 Y 1 C SER 974  ? B SER 974  
734  1 Y 1 C SER 975  ? B SER 975  
735  1 Y 1 C VAL 976  ? B VAL 976  
736  1 Y 1 C LEU 977  ? B LEU 977  
737  1 Y 1 C ASN 978  ? B ASN 978  
738  1 Y 1 C ASP 979  ? B ASP 979  
739  1 Y 1 C ILE 980  ? B ILE 980  
740  1 Y 1 C LEU 981  ? B LEU 981  
741  1 Y 1 C SER 982  ? B SER 982  
742  1 Y 1 C ARG 983  ? B ARG 983  
743  1 Y 1 C LEU 984  ? B LEU 984  
744  1 Y 1 C ASP 985  ? B ASP 985  
745  1 Y 1 C LYS 986  ? B LYS 986  
746  1 Y 1 C VAL 987  ? B VAL 987  
747  1 Y 1 C GLU 988  ? B GLU 988  
748  1 Y 1 C ALA 989  ? B ALA 989  
749  1 Y 1 C GLU 990  ? B GLU 990  
750  1 Y 1 C VAL 991  ? B VAL 991  
751  1 Y 1 C GLN 992  ? B GLN 992  
752  1 Y 1 C ILE 993  ? B ILE 993  
753  1 Y 1 C ASP 994  ? B ASP 994  
754  1 Y 1 C ARG 995  ? B ARG 995  
755  1 Y 1 C LEU 996  ? B LEU 996  
756  1 Y 1 C ILE 997  ? B ILE 997  
757  1 Y 1 C THR 998  ? B THR 998  
758  1 Y 1 C GLY 999  ? B GLY 999  
759  1 Y 1 C ARG 1000 ? B ARG 1000 
760  1 Y 1 C LEU 1001 ? B LEU 1001 
761  1 Y 1 C GLN 1002 ? B GLN 1002 
762  1 Y 1 C SER 1003 ? B SER 1003 
763  1 Y 1 C LEU 1004 ? B LEU 1004 
764  1 Y 1 C GLN 1005 ? B GLN 1005 
765  1 Y 1 C THR 1006 ? B THR 1006 
766  1 Y 1 C TYR 1007 ? B TYR 1007 
767  1 Y 1 C VAL 1008 ? B VAL 1008 
768  1 Y 1 C THR 1009 ? B THR 1009 
769  1 Y 1 C GLN 1010 ? B GLN 1010 
770  1 Y 1 C GLN 1011 ? B GLN 1011 
771  1 Y 1 C LEU 1012 ? B LEU 1012 
772  1 Y 1 C ILE 1013 ? B ILE 1013 
773  1 Y 1 C ARG 1014 ? B ARG 1014 
774  1 Y 1 C ALA 1015 ? B ALA 1015 
775  1 Y 1 C ALA 1016 ? B ALA 1016 
776  1 Y 1 C GLU 1017 ? B GLU 1017 
777  1 Y 1 C ILE 1018 ? B ILE 1018 
778  1 Y 1 C ARG 1019 ? B ARG 1019 
779  1 Y 1 C ALA 1020 ? B ALA 1020 
780  1 Y 1 C SER 1021 ? B SER 1021 
781  1 Y 1 C ALA 1022 ? B ALA 1022 
782  1 Y 1 C ASN 1023 ? B ASN 1023 
783  1 Y 1 C LEU 1024 ? B LEU 1024 
784  1 Y 1 C ALA 1025 ? B ALA 1025 
785  1 Y 1 C ALA 1026 ? B ALA 1026 
786  1 Y 1 C THR 1027 ? B THR 1027 
787  1 Y 1 C LYS 1028 ? B LYS 1028 
788  1 Y 1 C MET 1029 ? B MET 1029 
789  1 Y 1 C SER 1030 ? B SER 1030 
790  1 Y 1 C GLU 1031 ? B GLU 1031 
791  1 Y 1 C CYS 1032 ? B CYS 1032 
792  1 Y 1 C VAL 1033 ? B VAL 1033 
793  1 Y 1 C LEU 1034 ? B LEU 1034 
794  1 Y 1 C GLY 1035 ? B GLY 1035 
795  1 Y 1 C GLN 1036 ? B GLN 1036 
796  1 Y 1 C SER 1037 ? B SER 1037 
797  1 Y 1 C LYS 1038 ? B LYS 1038 
798  1 Y 1 C ARG 1039 ? B ARG 1039 
799  1 Y 1 C VAL 1040 ? B VAL 1040 
800  1 Y 1 C ASP 1041 ? B ASP 1041 
801  1 Y 1 C PHE 1042 ? B PHE 1042 
802  1 Y 1 C CYS 1043 ? B CYS 1043 
803  1 Y 1 C GLY 1044 ? B GLY 1044 
804  1 Y 1 C LYS 1045 ? B LYS 1045 
805  1 Y 1 C GLY 1046 ? B GLY 1046 
806  1 Y 1 C TYR 1047 ? B TYR 1047 
807  1 Y 1 C HIS 1048 ? B HIS 1048 
808  1 Y 1 C LEU 1049 ? B LEU 1049 
809  1 Y 1 C MET 1050 ? B MET 1050 
810  1 Y 1 C SER 1051 ? B SER 1051 
811  1 Y 1 C PHE 1052 ? B PHE 1052 
812  1 Y 1 C PRO 1053 ? B PRO 1053 
813  1 Y 1 C GLN 1054 ? B GLN 1054 
814  1 Y 1 C SER 1055 ? B SER 1055 
815  1 Y 1 C ALA 1056 ? B ALA 1056 
816  1 Y 1 C PRO 1057 ? B PRO 1057 
817  1 Y 1 C HIS 1058 ? B HIS 1058 
818  1 Y 1 C GLY 1059 ? B GLY 1059 
819  1 Y 1 C VAL 1060 ? B VAL 1060 
820  1 Y 1 C VAL 1061 ? B VAL 1061 
821  1 Y 1 C PHE 1062 ? B PHE 1062 
822  1 Y 1 C LEU 1063 ? B LEU 1063 
823  1 Y 1 C HIS 1064 ? B HIS 1064 
824  1 Y 1 C VAL 1065 ? B VAL 1065 
825  1 Y 1 C THR 1066 ? B THR 1066 
826  1 Y 1 C TYR 1067 ? B TYR 1067 
827  1 Y 1 C VAL 1068 ? B VAL 1068 
828  1 Y 1 C PRO 1069 ? B PRO 1069 
829  1 Y 1 C ALA 1070 ? B ALA 1070 
830  1 Y 1 C GLN 1071 ? B GLN 1071 
831  1 Y 1 C GLU 1072 ? B GLU 1072 
832  1 Y 1 C LYS 1073 ? B LYS 1073 
833  1 Y 1 C ASN 1074 ? B ASN 1074 
834  1 Y 1 C PHE 1075 ? B PHE 1075 
835  1 Y 1 C THR 1076 ? B THR 1076 
836  1 Y 1 C THR 1077 ? B THR 1077 
837  1 Y 1 C ALA 1078 ? B ALA 1078 
838  1 Y 1 C PRO 1079 ? B PRO 1079 
839  1 Y 1 C ALA 1080 ? B ALA 1080 
840  1 Y 1 C ILE 1081 ? B ILE 1081 
841  1 Y 1 C CYS 1082 ? B CYS 1082 
842  1 Y 1 C HIS 1083 ? B HIS 1083 
843  1 Y 1 C ASP 1084 ? B ASP 1084 
844  1 Y 1 C GLY 1085 ? B GLY 1085 
845  1 Y 1 C LYS 1086 ? B LYS 1086 
846  1 Y 1 C ALA 1087 ? B ALA 1087 
847  1 Y 1 C HIS 1088 ? B HIS 1088 
848  1 Y 1 C PHE 1089 ? B PHE 1089 
849  1 Y 1 C PRO 1090 ? B PRO 1090 
850  1 Y 1 C ARG 1091 ? B ARG 1091 
851  1 Y 1 C GLU 1092 ? B GLU 1092 
852  1 Y 1 C GLY 1093 ? B GLY 1093 
853  1 Y 1 C VAL 1094 ? B VAL 1094 
854  1 Y 1 C PHE 1095 ? B PHE 1095 
855  1 Y 1 C VAL 1096 ? B VAL 1096 
856  1 Y 1 C SER 1097 ? B SER 1097 
857  1 Y 1 C ASN 1098 ? B ASN 1098 
858  1 Y 1 C GLY 1099 ? B GLY 1099 
859  1 Y 1 C THR 1100 ? B THR 1100 
860  1 Y 1 C HIS 1101 ? B HIS 1101 
861  1 Y 1 C TRP 1102 ? B TRP 1102 
862  1 Y 1 C PHE 1103 ? B PHE 1103 
863  1 Y 1 C VAL 1104 ? B VAL 1104 
864  1 Y 1 C THR 1105 ? B THR 1105 
865  1 Y 1 C GLN 1106 ? B GLN 1106 
866  1 Y 1 C ARG 1107 ? B ARG 1107 
867  1 Y 1 C ASN 1108 ? B ASN 1108 
868  1 Y 1 C PHE 1109 ? B PHE 1109 
869  1 Y 1 C TYR 1110 ? B TYR 1110 
870  1 Y 1 C GLU 1111 ? B GLU 1111 
871  1 Y 1 C PRO 1112 ? B PRO 1112 
872  1 Y 1 C GLN 1113 ? B GLN 1113 
873  1 Y 1 C ILE 1114 ? B ILE 1114 
874  1 Y 1 C ILE 1115 ? B ILE 1115 
875  1 Y 1 C THR 1116 ? B THR 1116 
876  1 Y 1 C THR 1117 ? B THR 1117 
877  1 Y 1 C ASP 1118 ? B ASP 1118 
878  1 Y 1 C ASN 1119 ? B ASN 1119 
879  1 Y 1 C THR 1120 ? B THR 1120 
880  1 Y 1 C PHE 1121 ? B PHE 1121 
881  1 Y 1 C VAL 1122 ? B VAL 1122 
882  1 Y 1 C SER 1123 ? B SER 1123 
883  1 Y 1 C GLY 1124 ? B GLY 1124 
884  1 Y 1 C ASN 1125 ? B ASN 1125 
885  1 Y 1 C CYS 1126 ? B CYS 1126 
886  1 Y 1 C ASP 1127 ? B ASP 1127 
887  1 Y 1 C VAL 1128 ? B VAL 1128 
888  1 Y 1 C VAL 1129 ? B VAL 1129 
889  1 Y 1 C ILE 1130 ? B ILE 1130 
890  1 Y 1 C GLY 1131 ? B GLY 1131 
891  1 Y 1 C ILE 1132 ? B ILE 1132 
892  1 Y 1 C VAL 1133 ? B VAL 1133 
893  1 Y 1 C ASN 1134 ? B ASN 1134 
894  1 Y 1 C ASN 1135 ? B ASN 1135 
895  1 Y 1 C THR 1136 ? B THR 1136 
896  1 Y 1 C VAL 1137 ? B VAL 1137 
897  1 Y 1 C TYR 1138 ? B TYR 1138 
898  1 Y 1 C ASP 1139 ? B ASP 1139 
899  1 Y 1 C PRO 1140 ? B PRO 1140 
900  1 Y 1 C LEU 1141 ? B LEU 1141 
901  1 Y 1 C GLN 1142 ? B GLN 1142 
902  1 Y 1 C PRO 1143 ? B PRO 1143 
903  1 Y 1 C GLU 1144 ? B GLU 1144 
904  1 Y 1 C LEU 1145 ? B LEU 1145 
905  1 Y 1 C ASP 1146 ? B ASP 1146 
906  1 Y 1 C SER 1147 ? B SER 1147 
907  1 Y 1 C PHE 1148 ? B PHE 1148 
908  1 Y 1 C LYS 1149 ? B LYS 1149 
909  1 Y 1 C GLU 1150 ? B GLU 1150 
910  1 Y 1 C GLU 1151 ? B GLU 1151 
911  1 Y 1 C LEU 1152 ? B LEU 1152 
912  1 Y 1 C ASP 1153 ? B ASP 1153 
913  1 Y 1 C LYS 1154 ? B LYS 1154 
914  1 Y 1 C TYR 1155 ? B TYR 1155 
915  1 Y 1 C PHE 1156 ? B PHE 1156 
916  1 Y 1 C LYS 1157 ? B LYS 1157 
917  1 Y 1 C ASN 1158 ? B ASN 1158 
918  1 Y 1 C HIS 1159 ? B HIS 1159 
919  1 Y 1 C THR 1160 ? B THR 1160 
920  1 Y 1 C SER 1161 ? B SER 1161 
921  1 Y 1 C PRO 1162 ? B PRO 1162 
922  1 Y 1 C ASP 1163 ? B ASP 1163 
923  1 Y 1 C VAL 1164 ? B VAL 1164 
924  1 Y 1 C ASP 1165 ? B ASP 1165 
925  1 Y 1 C LEU 1166 ? B LEU 1166 
926  1 Y 1 C GLY 1167 ? B GLY 1167 
927  1 Y 1 C ASP 1168 ? B ASP 1168 
928  1 Y 1 C ILE 1169 ? B ILE 1169 
929  1 Y 1 C SER 1170 ? B SER 1170 
930  1 Y 1 C GLY 1171 ? B GLY 1171 
931  1 Y 1 C ILE 1172 ? B ILE 1172 
932  1 Y 1 C ASN 1173 ? B ASN 1173 
933  1 Y 1 C ALA 1174 ? B ALA 1174 
934  1 Y 1 C SER 1175 ? B SER 1175 
935  1 Y 1 C VAL 1176 ? B VAL 1176 
936  1 Y 1 C VAL 1177 ? B VAL 1177 
937  1 Y 1 C ASN 1178 ? B ASN 1178 
938  1 Y 1 C ILE 1179 ? B ILE 1179 
939  1 Y 1 C GLN 1180 ? B GLN 1180 
940  1 Y 1 C LYS 1181 ? B LYS 1181 
941  1 Y 1 C GLU 1182 ? B GLU 1182 
942  1 Y 1 C ILE 1183 ? B ILE 1183 
943  1 Y 1 C ASP 1184 ? B ASP 1184 
944  1 Y 1 C ARG 1185 ? B ARG 1185 
945  1 Y 1 C LEU 1186 ? B LEU 1186 
946  1 Y 1 C ASN 1187 ? B ASN 1187 
947  1 Y 1 C GLU 1188 ? B GLU 1188 
948  1 Y 1 C VAL 1189 ? B VAL 1189 
949  1 Y 1 C ALA 1190 ? B ALA 1190 
950  1 Y 1 C LYS 1191 ? B LYS 1191 
951  1 Y 1 C ASN 1192 ? B ASN 1192 
952  1 Y 1 C LEU 1193 ? B LEU 1193 
953  1 Y 1 C ASN 1194 ? B ASN 1194 
954  1 Y 1 C GLU 1195 ? B GLU 1195 
955  1 Y 1 C SER 1196 ? B SER 1196 
956  1 Y 1 C LEU 1197 ? B LEU 1197 
957  1 Y 1 C ILE 1198 ? B ILE 1198 
958  1 Y 1 C ASP 1199 ? B ASP 1199 
959  1 Y 1 C LEU 1200 ? B LEU 1200 
960  1 Y 1 C GLN 1201 ? B GLN 1201 
961  1 Y 1 C GLU 1202 ? B GLU 1202 
962  1 Y 1 C LEU 1203 ? B LEU 1203 
963  1 Y 1 C GLY 1204 ? B GLY 1204 
964  1 Y 1 C LYS 1205 ? B LYS 1205 
965  1 Y 1 C TYR 1206 ? B TYR 1206 
966  1 Y 1 C GLU 1207 ? B GLU 1207 
967  1 Y 1 C GLN 1208 ? B GLN 1208 
968  1 Y 1 C GLY 1209 ? B GLY 1209 
969  1 Y 1 C SER 1210 ? B SER 1210 
970  1 Y 1 C GLY 1211 ? B GLY 1211 
971  1 Y 1 C TYR 1212 ? B TYR 1212 
972  1 Y 1 C ILE 1213 ? B ILE 1213 
973  1 Y 1 C PRO 1214 ? B PRO 1214 
974  1 Y 1 C GLU 1215 ? B GLU 1215 
975  1 Y 1 C ALA 1216 ? B ALA 1216 
976  1 Y 1 C PRO 1217 ? B PRO 1217 
977  1 Y 1 C ARG 1218 ? B ARG 1218 
978  1 Y 1 C ASP 1219 ? B ASP 1219 
979  1 Y 1 C GLY 1220 ? B GLY 1220 
980  1 Y 1 C GLN 1221 ? B GLN 1221 
981  1 Y 1 C ALA 1222 ? B ALA 1222 
982  1 Y 1 C TYR 1223 ? B TYR 1223 
983  1 Y 1 C VAL 1224 ? B VAL 1224 
984  1 Y 1 C ARG 1225 ? B ARG 1225 
985  1 Y 1 C LYS 1226 ? B LYS 1226 
986  1 Y 1 C ASP 1227 ? B ASP 1227 
987  1 Y 1 C GLY 1228 ? B GLY 1228 
988  1 Y 1 C GLU 1229 ? B GLU 1229 
989  1 Y 1 C TRP 1230 ? B TRP 1230 
990  1 Y 1 C VAL 1231 ? B VAL 1231 
991  1 Y 1 C PHE 1232 ? B PHE 1232 
992  1 Y 1 C LEU 1233 ? B LEU 1233 
993  1 Y 1 C SER 1234 ? B SER 1234 
994  1 Y 1 C THR 1235 ? B THR 1235 
995  1 Y 1 C PHE 1236 ? B PHE 1236 
996  1 Y 1 C LEU 1237 ? B LEU 1237 
997  1 Y 1 C SER 1238 ? B SER 1238 
998  1 Y 1 C GLY 1239 ? B GLY 1239 
999  1 Y 1 C LEU 1240 ? B LEU 1240 
1000 1 Y 1 C GLU 1241 ? B GLU 1241 
1001 1 Y 1 C VAL 1242 ? B VAL 1242 
1002 1 Y 1 C LEU 1243 ? B LEU 1243 
1003 1 Y 1 C PHE 1244 ? B PHE 1244 
1004 1 Y 1 C GLN 1245 ? B GLN 1245 
1005 1 Y 1 C GLY 1246 ? B GLY 1246 
1006 1 Y 1 C PRO 1247 ? B PRO 1247 
1007 1 Y 1 C GLY 1248 ? B GLY 1248 
1008 1 Y 1 C GLY 1249 ? B GLY 1249 
1009 1 Y 1 C TRP 1250 ? B TRP 1250 
1010 1 Y 1 C SER 1251 ? B SER 1251 
1011 1 Y 1 C HIS 1252 ? B HIS 1252 
1012 1 Y 1 C PRO 1253 ? B PRO 1253 
1013 1 Y 1 C GLN 1254 ? B GLN 1254 
1014 1 Y 1 C PHE 1255 ? B PHE 1255 
1015 1 Y 1 C GLU 1256 ? B GLU 1256 
1016 1 Y 1 C LYS 1257 ? B LYS 1257 
1017 1 Y 1 C GLY 1258 ? B GLY 1258 
1018 1 Y 1 C GLY 1259 ? B GLY 1259 
1019 1 Y 1 C GLY 1260 ? B GLY 1260 
1020 1 Y 1 C SER 1261 ? B SER 1261 
1021 1 Y 1 C GLY 1262 ? B GLY 1262 
1022 1 Y 1 C GLY 1263 ? B GLY 1263 
1023 1 Y 1 C GLY 1264 ? B GLY 1264 
1024 1 Y 1 C SER 1265 ? B SER 1265 
1025 1 Y 1 C GLY 1266 ? B GLY 1266 
1026 1 Y 1 C GLY 1267 ? B GLY 1267 
1027 1 Y 1 C SER 1268 ? B SER 1268 
1028 1 Y 1 C ALA 1269 ? B ALA 1269 
1029 1 Y 1 C TRP 1270 ? B TRP 1270 
1030 1 Y 1 C SER 1271 ? B SER 1271 
1031 1 Y 1 C HIS 1272 ? B HIS 1272 
1032 1 Y 1 C PRO 1273 ? B PRO 1273 
1033 1 Y 1 C GLN 1274 ? B GLN 1274 
1034 1 Y 1 C PHE 1275 ? B PHE 1275 
1035 1 Y 1 C GLU 1276 ? B GLU 1276 
1036 1 Y 1 C LYS 1277 ? B LYS 1277 
1037 1 Y 1 C GLY 1278 ? B GLY 1278 
1038 1 Y 1 C GLY 1279 ? B GLY 1279 
1039 1 Y 1 C SER 1280 ? B SER 1280 
1040 1 Y 1 C HIS 1281 ? B HIS 1281 
1041 1 Y 1 C HIS 1282 ? B HIS 1282 
1042 1 Y 1 C HIS 1283 ? B HIS 1283 
1043 1 Y 1 C HIS 1284 ? B HIS 1284 
1044 1 Y 1 C HIS 1285 ? B HIS 1285 
1045 1 Y 1 C HIS 1286 ? B HIS 1286 
1046 1 Y 1 C HIS 1287 ? B HIS 1287 
1047 1 Y 1 C HIS 1288 ? B HIS 1288 
1048 1 Y 1 A MET 1    ? C MET 1    
1049 1 Y 1 A PHE 2    ? C PHE 2    
1050 1 Y 1 A VAL 3    ? C VAL 3    
1051 1 Y 1 A PHE 4    ? C PHE 4    
1052 1 Y 1 A LEU 5    ? C LEU 5    
1053 1 Y 1 A VAL 6    ? C VAL 6    
1054 1 Y 1 A LEU 7    ? C LEU 7    
1055 1 Y 1 A LEU 8    ? C LEU 8    
1056 1 Y 1 A PRO 9    ? C PRO 9    
1057 1 Y 1 A LEU 10   ? C LEU 10   
1058 1 Y 1 A VAL 11   ? C VAL 11   
1059 1 Y 1 A SER 12   ? C SER 12   
1060 1 Y 1 A SER 13   ? C SER 13   
1061 1 Y 1 A GLN 14   ? C GLN 14   
1062 1 Y 1 A CYS 15   ? C CYS 15   
1063 1 Y 1 A VAL 16   ? C VAL 16   
1064 1 Y 1 A ASN 17   ? C ASN 17   
1065 1 Y 1 A LEU 18   ? C LEU 18   
1066 1 Y 1 A THR 19   ? C THR 19   
1067 1 Y 1 A THR 20   ? C THR 20   
1068 1 Y 1 A ARG 21   ? C ARG 21   
1069 1 Y 1 A THR 22   ? C THR 22   
1070 1 Y 1 A GLN 23   ? C GLN 23   
1071 1 Y 1 A LEU 24   ? C LEU 24   
1072 1 Y 1 A PRO 25   ? C PRO 25   
1073 1 Y 1 A PRO 26   ? C PRO 26   
1074 1 Y 1 A ALA 27   ? C ALA 27   
1075 1 Y 1 A TYR 28   ? C TYR 28   
1076 1 Y 1 A THR 29   ? C THR 29   
1077 1 Y 1 A ASN 30   ? C ASN 30   
1078 1 Y 1 A SER 31   ? C SER 31   
1079 1 Y 1 A PHE 32   ? C PHE 32   
1080 1 Y 1 A THR 33   ? C THR 33   
1081 1 Y 1 A ARG 34   ? C ARG 34   
1082 1 Y 1 A GLY 35   ? C GLY 35   
1083 1 Y 1 A VAL 36   ? C VAL 36   
1084 1 Y 1 A TYR 37   ? C TYR 37   
1085 1 Y 1 A TYR 38   ? C TYR 38   
1086 1 Y 1 A PRO 39   ? C PRO 39   
1087 1 Y 1 A ASP 40   ? C ASP 40   
1088 1 Y 1 A LYS 41   ? C LYS 41   
1089 1 Y 1 A VAL 42   ? C VAL 42   
1090 1 Y 1 A PHE 43   ? C PHE 43   
1091 1 Y 1 A ARG 44   ? C ARG 44   
1092 1 Y 1 A SER 45   ? C SER 45   
1093 1 Y 1 A SER 46   ? C SER 46   
1094 1 Y 1 A VAL 47   ? C VAL 47   
1095 1 Y 1 A LEU 48   ? C LEU 48   
1096 1 Y 1 A HIS 49   ? C HIS 49   
1097 1 Y 1 A SER 50   ? C SER 50   
1098 1 Y 1 A THR 51   ? C THR 51   
1099 1 Y 1 A GLN 52   ? C GLN 52   
1100 1 Y 1 A ASP 53   ? C ASP 53   
1101 1 Y 1 A LEU 54   ? C LEU 54   
1102 1 Y 1 A PHE 55   ? C PHE 55   
1103 1 Y 1 A LEU 56   ? C LEU 56   
1104 1 Y 1 A PRO 57   ? C PRO 57   
1105 1 Y 1 A PHE 58   ? C PHE 58   
1106 1 Y 1 A PHE 59   ? C PHE 59   
1107 1 Y 1 A SER 60   ? C SER 60   
1108 1 Y 1 A ASN 61   ? C ASN 61   
1109 1 Y 1 A VAL 62   ? C VAL 62   
1110 1 Y 1 A THR 63   ? C THR 63   
1111 1 Y 1 A TRP 64   ? C TRP 64   
1112 1 Y 1 A PHE 65   ? C PHE 65   
1113 1 Y 1 A HIS 66   ? C HIS 66   
1114 1 Y 1 A ALA 67   ? C ALA 67   
1115 1 Y 1 A ILE 68   ? C ILE 68   
1116 1 Y 1 A HIS 69   ? C HIS 69   
1117 1 Y 1 A VAL 70   ? C VAL 70   
1118 1 Y 1 A SER 71   ? C SER 71   
1119 1 Y 1 A GLY 72   ? C GLY 72   
1120 1 Y 1 A THR 73   ? C THR 73   
1121 1 Y 1 A ASN 74   ? C ASN 74   
1122 1 Y 1 A GLY 75   ? C GLY 75   
1123 1 Y 1 A THR 76   ? C THR 76   
1124 1 Y 1 A LYS 77   ? C LYS 77   
1125 1 Y 1 A ARG 78   ? C ARG 78   
1126 1 Y 1 A PHE 79   ? C PHE 79   
1127 1 Y 1 A ASP 80   ? C ASP 80   
1128 1 Y 1 A ASN 81   ? C ASN 81   
1129 1 Y 1 A PRO 82   ? C PRO 82   
1130 1 Y 1 A VAL 83   ? C VAL 83   
1131 1 Y 1 A LEU 84   ? C LEU 84   
1132 1 Y 1 A PRO 85   ? C PRO 85   
1133 1 Y 1 A PHE 86   ? C PHE 86   
1134 1 Y 1 A ASN 87   ? C ASN 87   
1135 1 Y 1 A ASP 88   ? C ASP 88   
1136 1 Y 1 A GLY 89   ? C GLY 89   
1137 1 Y 1 A VAL 90   ? C VAL 90   
1138 1 Y 1 A TYR 91   ? C TYR 91   
1139 1 Y 1 A PHE 92   ? C PHE 92   
1140 1 Y 1 A ALA 93   ? C ALA 93   
1141 1 Y 1 A SER 94   ? C SER 94   
1142 1 Y 1 A THR 95   ? C THR 95   
1143 1 Y 1 A GLU 96   ? C GLU 96   
1144 1 Y 1 A LYS 97   ? C LYS 97   
1145 1 Y 1 A SER 98   ? C SER 98   
1146 1 Y 1 A ASN 99   ? C ASN 99   
1147 1 Y 1 A ILE 100  ? C ILE 100  
1148 1 Y 1 A ILE 101  ? C ILE 101  
1149 1 Y 1 A ARG 102  ? C ARG 102  
1150 1 Y 1 A GLY 103  ? C GLY 103  
1151 1 Y 1 A TRP 104  ? C TRP 104  
1152 1 Y 1 A ILE 105  ? C ILE 105  
1153 1 Y 1 A PHE 106  ? C PHE 106  
1154 1 Y 1 A GLY 107  ? C GLY 107  
1155 1 Y 1 A THR 108  ? C THR 108  
1156 1 Y 1 A THR 109  ? C THR 109  
1157 1 Y 1 A LEU 110  ? C LEU 110  
1158 1 Y 1 A ASP 111  ? C ASP 111  
1159 1 Y 1 A SER 112  ? C SER 112  
1160 1 Y 1 A LYS 113  ? C LYS 113  
1161 1 Y 1 A THR 114  ? C THR 114  
1162 1 Y 1 A GLN 115  ? C GLN 115  
1163 1 Y 1 A SER 116  ? C SER 116  
1164 1 Y 1 A LEU 117  ? C LEU 117  
1165 1 Y 1 A LEU 118  ? C LEU 118  
1166 1 Y 1 A ILE 119  ? C ILE 119  
1167 1 Y 1 A VAL 120  ? C VAL 120  
1168 1 Y 1 A ASN 121  ? C ASN 121  
1169 1 Y 1 A ASN 122  ? C ASN 122  
1170 1 Y 1 A ALA 123  ? C ALA 123  
1171 1 Y 1 A THR 124  ? C THR 124  
1172 1 Y 1 A ASN 125  ? C ASN 125  
1173 1 Y 1 A VAL 126  ? C VAL 126  
1174 1 Y 1 A VAL 127  ? C VAL 127  
1175 1 Y 1 A ILE 128  ? C ILE 128  
1176 1 Y 1 A LYS 129  ? C LYS 129  
1177 1 Y 1 A VAL 130  ? C VAL 130  
1178 1 Y 1 A CYS 131  ? C CYS 131  
1179 1 Y 1 A GLU 132  ? C GLU 132  
1180 1 Y 1 A PHE 133  ? C PHE 133  
1181 1 Y 1 A GLN 134  ? C GLN 134  
1182 1 Y 1 A PHE 135  ? C PHE 135  
1183 1 Y 1 A CYS 136  ? C CYS 136  
1184 1 Y 1 A ASN 137  ? C ASN 137  
1185 1 Y 1 A ASP 138  ? C ASP 138  
1186 1 Y 1 A PRO 139  ? C PRO 139  
1187 1 Y 1 A PHE 140  ? C PHE 140  
1188 1 Y 1 A LEU 141  ? C LEU 141  
1189 1 Y 1 A GLY 142  ? C GLY 142  
1190 1 Y 1 A VAL 143  ? C VAL 143  
1191 1 Y 1 A TYR 144  ? C TYR 144  
1192 1 Y 1 A TYR 145  ? C TYR 145  
1193 1 Y 1 A HIS 146  ? C HIS 146  
1194 1 Y 1 A LYS 147  ? C LYS 147  
1195 1 Y 1 A ASN 148  ? C ASN 148  
1196 1 Y 1 A ASN 149  ? C ASN 149  
1197 1 Y 1 A LYS 150  ? C LYS 150  
1198 1 Y 1 A SER 151  ? C SER 151  
1199 1 Y 1 A TRP 152  ? C TRP 152  
1200 1 Y 1 A MET 153  ? C MET 153  
1201 1 Y 1 A GLU 154  ? C GLU 154  
1202 1 Y 1 A SER 155  ? C SER 155  
1203 1 Y 1 A GLU 156  ? C GLU 156  
1204 1 Y 1 A PHE 157  ? C PHE 157  
1205 1 Y 1 A ARG 158  ? C ARG 158  
1206 1 Y 1 A VAL 159  ? C VAL 159  
1207 1 Y 1 A TYR 160  ? C TYR 160  
1208 1 Y 1 A SER 161  ? C SER 161  
1209 1 Y 1 A SER 162  ? C SER 162  
1210 1 Y 1 A ALA 163  ? C ALA 163  
1211 1 Y 1 A ASN 164  ? C ASN 164  
1212 1 Y 1 A ASN 165  ? C ASN 165  
1213 1 Y 1 A CYS 166  ? C CYS 166  
1214 1 Y 1 A THR 167  ? C THR 167  
1215 1 Y 1 A PHE 168  ? C PHE 168  
1216 1 Y 1 A GLU 169  ? C GLU 169  
1217 1 Y 1 A TYR 170  ? C TYR 170  
1218 1 Y 1 A VAL 171  ? C VAL 171  
1219 1 Y 1 A SER 172  ? C SER 172  
1220 1 Y 1 A GLN 173  ? C GLN 173  
1221 1 Y 1 A PRO 174  ? C PRO 174  
1222 1 Y 1 A PHE 175  ? C PHE 175  
1223 1 Y 1 A LEU 176  ? C LEU 176  
1224 1 Y 1 A MET 177  ? C MET 177  
1225 1 Y 1 A ASP 178  ? C ASP 178  
1226 1 Y 1 A LEU 179  ? C LEU 179  
1227 1 Y 1 A GLU 180  ? C GLU 180  
1228 1 Y 1 A GLY 181  ? C GLY 181  
1229 1 Y 1 A LYS 182  ? C LYS 182  
1230 1 Y 1 A GLN 183  ? C GLN 183  
1231 1 Y 1 A GLY 184  ? C GLY 184  
1232 1 Y 1 A ASN 185  ? C ASN 185  
1233 1 Y 1 A PHE 186  ? C PHE 186  
1234 1 Y 1 A LYS 187  ? C LYS 187  
1235 1 Y 1 A ASN 188  ? C ASN 188  
1236 1 Y 1 A LEU 189  ? C LEU 189  
1237 1 Y 1 A ARG 190  ? C ARG 190  
1238 1 Y 1 A GLU 191  ? C GLU 191  
1239 1 Y 1 A PHE 192  ? C PHE 192  
1240 1 Y 1 A VAL 193  ? C VAL 193  
1241 1 Y 1 A PHE 194  ? C PHE 194  
1242 1 Y 1 A LYS 195  ? C LYS 195  
1243 1 Y 1 A ASN 196  ? C ASN 196  
1244 1 Y 1 A ILE 197  ? C ILE 197  
1245 1 Y 1 A ASP 198  ? C ASP 198  
1246 1 Y 1 A GLY 199  ? C GLY 199  
1247 1 Y 1 A TYR 200  ? C TYR 200  
1248 1 Y 1 A PHE 201  ? C PHE 201  
1249 1 Y 1 A LYS 202  ? C LYS 202  
1250 1 Y 1 A ILE 203  ? C ILE 203  
1251 1 Y 1 A TYR 204  ? C TYR 204  
1252 1 Y 1 A SER 205  ? C SER 205  
1253 1 Y 1 A LYS 206  ? C LYS 206  
1254 1 Y 1 A HIS 207  ? C HIS 207  
1255 1 Y 1 A THR 208  ? C THR 208  
1256 1 Y 1 A PRO 209  ? C PRO 209  
1257 1 Y 1 A ILE 210  ? C ILE 210  
1258 1 Y 1 A ASN 211  ? C ASN 211  
1259 1 Y 1 A LEU 212  ? C LEU 212  
1260 1 Y 1 A VAL 213  ? C VAL 213  
1261 1 Y 1 A ARG 214  ? C ARG 214  
1262 1 Y 1 A ASP 215  ? C ASP 215  
1263 1 Y 1 A LEU 216  ? C LEU 216  
1264 1 Y 1 A PRO 217  ? C PRO 217  
1265 1 Y 1 A GLN 218  ? C GLN 218  
1266 1 Y 1 A GLY 219  ? C GLY 219  
1267 1 Y 1 A PHE 220  ? C PHE 220  
1268 1 Y 1 A SER 221  ? C SER 221  
1269 1 Y 1 A ALA 222  ? C ALA 222  
1270 1 Y 1 A LEU 223  ? C LEU 223  
1271 1 Y 1 A GLU 224  ? C GLU 224  
1272 1 Y 1 A PRO 225  ? C PRO 225  
1273 1 Y 1 A LEU 226  ? C LEU 226  
1274 1 Y 1 A VAL 227  ? C VAL 227  
1275 1 Y 1 A ASP 228  ? C ASP 228  
1276 1 Y 1 A LEU 229  ? C LEU 229  
1277 1 Y 1 A PRO 230  ? C PRO 230  
1278 1 Y 1 A ILE 231  ? C ILE 231  
1279 1 Y 1 A GLY 232  ? C GLY 232  
1280 1 Y 1 A ILE 233  ? C ILE 233  
1281 1 Y 1 A ASN 234  ? C ASN 234  
1282 1 Y 1 A ILE 235  ? C ILE 235  
1283 1 Y 1 A THR 236  ? C THR 236  
1284 1 Y 1 A ARG 237  ? C ARG 237  
1285 1 Y 1 A PHE 238  ? C PHE 238  
1286 1 Y 1 A GLN 239  ? C GLN 239  
1287 1 Y 1 A THR 240  ? C THR 240  
1288 1 Y 1 A LEU 241  ? C LEU 241  
1289 1 Y 1 A LEU 242  ? C LEU 242  
1290 1 Y 1 A ALA 243  ? C ALA 243  
1291 1 Y 1 A LEU 244  ? C LEU 244  
1292 1 Y 1 A HIS 245  ? C HIS 245  
1293 1 Y 1 A ARG 246  ? C ARG 246  
1294 1 Y 1 A SER 247  ? C SER 247  
1295 1 Y 1 A TYR 248  ? C TYR 248  
1296 1 Y 1 A LEU 249  ? C LEU 249  
1297 1 Y 1 A THR 250  ? C THR 250  
1298 1 Y 1 A PRO 251  ? C PRO 251  
1299 1 Y 1 A GLY 252  ? C GLY 252  
1300 1 Y 1 A ASP 253  ? C ASP 253  
1301 1 Y 1 A SER 254  ? C SER 254  
1302 1 Y 1 A SER 255  ? C SER 255  
1303 1 Y 1 A SER 256  ? C SER 256  
1304 1 Y 1 A GLY 257  ? C GLY 257  
1305 1 Y 1 A TRP 258  ? C TRP 258  
1306 1 Y 1 A THR 259  ? C THR 259  
1307 1 Y 1 A ALA 260  ? C ALA 260  
1308 1 Y 1 A GLY 261  ? C GLY 261  
1309 1 Y 1 A ALA 262  ? C ALA 262  
1310 1 Y 1 A ALA 263  ? C ALA 263  
1311 1 Y 1 A ALA 264  ? C ALA 264  
1312 1 Y 1 A TYR 265  ? C TYR 265  
1313 1 Y 1 A TYR 266  ? C TYR 266  
1314 1 Y 1 A VAL 267  ? C VAL 267  
1315 1 Y 1 A GLY 268  ? C GLY 268  
1316 1 Y 1 A TYR 269  ? C TYR 269  
1317 1 Y 1 A LEU 270  ? C LEU 270  
1318 1 Y 1 A GLN 271  ? C GLN 271  
1319 1 Y 1 A PRO 272  ? C PRO 272  
1320 1 Y 1 A ARG 273  ? C ARG 273  
1321 1 Y 1 A THR 274  ? C THR 274  
1322 1 Y 1 A PHE 275  ? C PHE 275  
1323 1 Y 1 A LEU 276  ? C LEU 276  
1324 1 Y 1 A LEU 277  ? C LEU 277  
1325 1 Y 1 A LYS 278  ? C LYS 278  
1326 1 Y 1 A TYR 279  ? C TYR 279  
1327 1 Y 1 A ASN 280  ? C ASN 280  
1328 1 Y 1 A GLU 281  ? C GLU 281  
1329 1 Y 1 A ASN 282  ? C ASN 282  
1330 1 Y 1 A GLY 283  ? C GLY 283  
1331 1 Y 1 A THR 284  ? C THR 284  
1332 1 Y 1 A ILE 285  ? C ILE 285  
1333 1 Y 1 A THR 286  ? C THR 286  
1334 1 Y 1 A ASP 287  ? C ASP 287  
1335 1 Y 1 A ALA 288  ? C ALA 288  
1336 1 Y 1 A VAL 289  ? C VAL 289  
1337 1 Y 1 A ASP 290  ? C ASP 290  
1338 1 Y 1 A CYS 291  ? C CYS 291  
1339 1 Y 1 A ALA 292  ? C ALA 292  
1340 1 Y 1 A LEU 293  ? C LEU 293  
1341 1 Y 1 A ASP 294  ? C ASP 294  
1342 1 Y 1 A PRO 295  ? C PRO 295  
1343 1 Y 1 A LEU 296  ? C LEU 296  
1344 1 Y 1 A SER 297  ? C SER 297  
1345 1 Y 1 A GLU 298  ? C GLU 298  
1346 1 Y 1 A THR 299  ? C THR 299  
1347 1 Y 1 A LYS 300  ? C LYS 300  
1348 1 Y 1 A CYS 301  ? C CYS 301  
1349 1 Y 1 A THR 302  ? C THR 302  
1350 1 Y 1 A LEU 303  ? C LEU 303  
1351 1 Y 1 A LYS 304  ? C LYS 304  
1352 1 Y 1 A SER 305  ? C SER 305  
1353 1 Y 1 A PHE 306  ? C PHE 306  
1354 1 Y 1 A THR 307  ? C THR 307  
1355 1 Y 1 A VAL 308  ? C VAL 308  
1356 1 Y 1 A GLU 309  ? C GLU 309  
1357 1 Y 1 A LYS 310  ? C LYS 310  
1358 1 Y 1 A GLY 311  ? C GLY 311  
1359 1 Y 1 A ILE 312  ? C ILE 312  
1360 1 Y 1 A TYR 313  ? C TYR 313  
1361 1 Y 1 A GLN 314  ? C GLN 314  
1362 1 Y 1 A THR 315  ? C THR 315  
1363 1 Y 1 A SER 316  ? C SER 316  
1364 1 Y 1 A ASN 317  ? C ASN 317  
1365 1 Y 1 A PHE 318  ? C PHE 318  
1366 1 Y 1 A ARG 319  ? C ARG 319  
1367 1 Y 1 A GLY 593  ? C GLY 593  
1368 1 Y 1 A GLY 594  ? C GLY 594  
1369 1 Y 1 A VAL 595  ? C VAL 595  
1370 1 Y 1 A SER 596  ? C SER 596  
1371 1 Y 1 A VAL 597  ? C VAL 597  
1372 1 Y 1 A ILE 598  ? C ILE 598  
1373 1 Y 1 A THR 599  ? C THR 599  
1374 1 Y 1 A PRO 600  ? C PRO 600  
1375 1 Y 1 A GLY 601  ? C GLY 601  
1376 1 Y 1 A THR 602  ? C THR 602  
1377 1 Y 1 A ASN 603  ? C ASN 603  
1378 1 Y 1 A THR 604  ? C THR 604  
1379 1 Y 1 A SER 605  ? C SER 605  
1380 1 Y 1 A ASN 606  ? C ASN 606  
1381 1 Y 1 A GLN 607  ? C GLN 607  
1382 1 Y 1 A VAL 608  ? C VAL 608  
1383 1 Y 1 A ALA 609  ? C ALA 609  
1384 1 Y 1 A VAL 610  ? C VAL 610  
1385 1 Y 1 A LEU 611  ? C LEU 611  
1386 1 Y 1 A TYR 612  ? C TYR 612  
1387 1 Y 1 A GLN 613  ? C GLN 613  
1388 1 Y 1 A GLY 614  ? C GLY 614  
1389 1 Y 1 A VAL 615  ? C VAL 615  
1390 1 Y 1 A ASN 616  ? C ASN 616  
1391 1 Y 1 A CYS 617  ? C CYS 617  
1392 1 Y 1 A THR 618  ? C THR 618  
1393 1 Y 1 A GLU 619  ? C GLU 619  
1394 1 Y 1 A VAL 620  ? C VAL 620  
1395 1 Y 1 A PRO 621  ? C PRO 621  
1396 1 Y 1 A VAL 622  ? C VAL 622  
1397 1 Y 1 A ALA 623  ? C ALA 623  
1398 1 Y 1 A ILE 624  ? C ILE 624  
1399 1 Y 1 A HIS 625  ? C HIS 625  
1400 1 Y 1 A ALA 626  ? C ALA 626  
1401 1 Y 1 A ASP 627  ? C ASP 627  
1402 1 Y 1 A GLN 628  ? C GLN 628  
1403 1 Y 1 A LEU 629  ? C LEU 629  
1404 1 Y 1 A THR 630  ? C THR 630  
1405 1 Y 1 A PRO 631  ? C PRO 631  
1406 1 Y 1 A THR 632  ? C THR 632  
1407 1 Y 1 A TRP 633  ? C TRP 633  
1408 1 Y 1 A ARG 634  ? C ARG 634  
1409 1 Y 1 A VAL 635  ? C VAL 635  
1410 1 Y 1 A TYR 636  ? C TYR 636  
1411 1 Y 1 A SER 637  ? C SER 637  
1412 1 Y 1 A THR 638  ? C THR 638  
1413 1 Y 1 A GLY 639  ? C GLY 639  
1414 1 Y 1 A SER 640  ? C SER 640  
1415 1 Y 1 A ASN 641  ? C ASN 641  
1416 1 Y 1 A VAL 642  ? C VAL 642  
1417 1 Y 1 A PHE 643  ? C PHE 643  
1418 1 Y 1 A GLN 644  ? C GLN 644  
1419 1 Y 1 A THR 645  ? C THR 645  
1420 1 Y 1 A ARG 646  ? C ARG 646  
1421 1 Y 1 A ALA 647  ? C ALA 647  
1422 1 Y 1 A GLY 648  ? C GLY 648  
1423 1 Y 1 A CYS 649  ? C CYS 649  
1424 1 Y 1 A LEU 650  ? C LEU 650  
1425 1 Y 1 A ILE 651  ? C ILE 651  
1426 1 Y 1 A GLY 652  ? C GLY 652  
1427 1 Y 1 A ALA 653  ? C ALA 653  
1428 1 Y 1 A GLU 654  ? C GLU 654  
1429 1 Y 1 A HIS 655  ? C HIS 655  
1430 1 Y 1 A VAL 656  ? C VAL 656  
1431 1 Y 1 A ASN 657  ? C ASN 657  
1432 1 Y 1 A ASN 658  ? C ASN 658  
1433 1 Y 1 A SER 659  ? C SER 659  
1434 1 Y 1 A TYR 660  ? C TYR 660  
1435 1 Y 1 A GLU 661  ? C GLU 661  
1436 1 Y 1 A CYS 662  ? C CYS 662  
1437 1 Y 1 A ASP 663  ? C ASP 663  
1438 1 Y 1 A ILE 664  ? C ILE 664  
1439 1 Y 1 A PRO 665  ? C PRO 665  
1440 1 Y 1 A ILE 666  ? C ILE 666  
1441 1 Y 1 A GLY 667  ? C GLY 667  
1442 1 Y 1 A ALA 668  ? C ALA 668  
1443 1 Y 1 A GLY 669  ? C GLY 669  
1444 1 Y 1 A ILE 670  ? C ILE 670  
1445 1 Y 1 A CYS 671  ? C CYS 671  
1446 1 Y 1 A ALA 672  ? C ALA 672  
1447 1 Y 1 A SER 673  ? C SER 673  
1448 1 Y 1 A TYR 674  ? C TYR 674  
1449 1 Y 1 A GLN 675  ? C GLN 675  
1450 1 Y 1 A THR 676  ? C THR 676  
1451 1 Y 1 A GLN 677  ? C GLN 677  
1452 1 Y 1 A THR 678  ? C THR 678  
1453 1 Y 1 A ASN 679  ? C ASN 679  
1454 1 Y 1 A SER 680  ? C SER 680  
1455 1 Y 1 A PRO 681  ? C PRO 681  
1456 1 Y 1 A ARG 682  ? C ARG 682  
1457 1 Y 1 A ARG 683  ? C ARG 683  
1458 1 Y 1 A ALA 684  ? C ALA 684  
1459 1 Y 1 A ARG 685  ? C ARG 685  
1460 1 Y 1 A SER 686  ? C SER 686  
1461 1 Y 1 A VAL 687  ? C VAL 687  
1462 1 Y 1 A ALA 688  ? C ALA 688  
1463 1 Y 1 A SER 689  ? C SER 689  
1464 1 Y 1 A GLN 690  ? C GLN 690  
1465 1 Y 1 A SER 691  ? C SER 691  
1466 1 Y 1 A ILE 692  ? C ILE 692  
1467 1 Y 1 A ILE 693  ? C ILE 693  
1468 1 Y 1 A ALA 694  ? C ALA 694  
1469 1 Y 1 A TYR 695  ? C TYR 695  
1470 1 Y 1 A THR 696  ? C THR 696  
1471 1 Y 1 A MET 697  ? C MET 697  
1472 1 Y 1 A SER 698  ? C SER 698  
1473 1 Y 1 A LEU 699  ? C LEU 699  
1474 1 Y 1 A GLY 700  ? C GLY 700  
1475 1 Y 1 A ALA 701  ? C ALA 701  
1476 1 Y 1 A GLU 702  ? C GLU 702  
1477 1 Y 1 A ASN 703  ? C ASN 703  
1478 1 Y 1 A SER 704  ? C SER 704  
1479 1 Y 1 A VAL 705  ? C VAL 705  
1480 1 Y 1 A ALA 706  ? C ALA 706  
1481 1 Y 1 A TYR 707  ? C TYR 707  
1482 1 Y 1 A SER 708  ? C SER 708  
1483 1 Y 1 A ASN 709  ? C ASN 709  
1484 1 Y 1 A ASN 710  ? C ASN 710  
1485 1 Y 1 A SER 711  ? C SER 711  
1486 1 Y 1 A ILE 712  ? C ILE 712  
1487 1 Y 1 A ALA 713  ? C ALA 713  
1488 1 Y 1 A ILE 714  ? C ILE 714  
1489 1 Y 1 A PRO 715  ? C PRO 715  
1490 1 Y 1 A THR 716  ? C THR 716  
1491 1 Y 1 A ASN 717  ? C ASN 717  
1492 1 Y 1 A PHE 718  ? C PHE 718  
1493 1 Y 1 A THR 719  ? C THR 719  
1494 1 Y 1 A ILE 720  ? C ILE 720  
1495 1 Y 1 A SER 721  ? C SER 721  
1496 1 Y 1 A VAL 722  ? C VAL 722  
1497 1 Y 1 A THR 723  ? C THR 723  
1498 1 Y 1 A THR 724  ? C THR 724  
1499 1 Y 1 A GLU 725  ? C GLU 725  
1500 1 Y 1 A ILE 726  ? C ILE 726  
1501 1 Y 1 A LEU 727  ? C LEU 727  
1502 1 Y 1 A PRO 728  ? C PRO 728  
1503 1 Y 1 A VAL 729  ? C VAL 729  
1504 1 Y 1 A SER 730  ? C SER 730  
1505 1 Y 1 A MET 731  ? C MET 731  
1506 1 Y 1 A THR 732  ? C THR 732  
1507 1 Y 1 A LYS 733  ? C LYS 733  
1508 1 Y 1 A THR 734  ? C THR 734  
1509 1 Y 1 A SER 735  ? C SER 735  
1510 1 Y 1 A VAL 736  ? C VAL 736  
1511 1 Y 1 A ASP 737  ? C ASP 737  
1512 1 Y 1 A CYS 738  ? C CYS 738  
1513 1 Y 1 A THR 739  ? C THR 739  
1514 1 Y 1 A MET 740  ? C MET 740  
1515 1 Y 1 A TYR 741  ? C TYR 741  
1516 1 Y 1 A ILE 742  ? C ILE 742  
1517 1 Y 1 A CYS 743  ? C CYS 743  
1518 1 Y 1 A GLY 744  ? C GLY 744  
1519 1 Y 1 A ASP 745  ? C ASP 745  
1520 1 Y 1 A SER 746  ? C SER 746  
1521 1 Y 1 A THR 747  ? C THR 747  
1522 1 Y 1 A GLU 748  ? C GLU 748  
1523 1 Y 1 A CYS 749  ? C CYS 749  
1524 1 Y 1 A SER 750  ? C SER 750  
1525 1 Y 1 A ASN 751  ? C ASN 751  
1526 1 Y 1 A LEU 752  ? C LEU 752  
1527 1 Y 1 A LEU 753  ? C LEU 753  
1528 1 Y 1 A LEU 754  ? C LEU 754  
1529 1 Y 1 A GLN 755  ? C GLN 755  
1530 1 Y 1 A TYR 756  ? C TYR 756  
1531 1 Y 1 A GLY 757  ? C GLY 757  
1532 1 Y 1 A SER 758  ? C SER 758  
1533 1 Y 1 A PHE 759  ? C PHE 759  
1534 1 Y 1 A CYS 760  ? C CYS 760  
1535 1 Y 1 A THR 761  ? C THR 761  
1536 1 Y 1 A GLN 762  ? C GLN 762  
1537 1 Y 1 A LEU 763  ? C LEU 763  
1538 1 Y 1 A ASN 764  ? C ASN 764  
1539 1 Y 1 A ARG 765  ? C ARG 765  
1540 1 Y 1 A ALA 766  ? C ALA 766  
1541 1 Y 1 A LEU 767  ? C LEU 767  
1542 1 Y 1 A THR 768  ? C THR 768  
1543 1 Y 1 A GLY 769  ? C GLY 769  
1544 1 Y 1 A ILE 770  ? C ILE 770  
1545 1 Y 1 A ALA 771  ? C ALA 771  
1546 1 Y 1 A VAL 772  ? C VAL 772  
1547 1 Y 1 A GLU 773  ? C GLU 773  
1548 1 Y 1 A GLN 774  ? C GLN 774  
1549 1 Y 1 A ASP 775  ? C ASP 775  
1550 1 Y 1 A LYS 776  ? C LYS 776  
1551 1 Y 1 A ASN 777  ? C ASN 777  
1552 1 Y 1 A THR 778  ? C THR 778  
1553 1 Y 1 A GLN 779  ? C GLN 779  
1554 1 Y 1 A GLU 780  ? C GLU 780  
1555 1 Y 1 A VAL 781  ? C VAL 781  
1556 1 Y 1 A PHE 782  ? C PHE 782  
1557 1 Y 1 A ALA 783  ? C ALA 783  
1558 1 Y 1 A GLN 784  ? C GLN 784  
1559 1 Y 1 A VAL 785  ? C VAL 785  
1560 1 Y 1 A LYS 786  ? C LYS 786  
1561 1 Y 1 A GLN 787  ? C GLN 787  
1562 1 Y 1 A ILE 788  ? C ILE 788  
1563 1 Y 1 A TYR 789  ? C TYR 789  
1564 1 Y 1 A LYS 790  ? C LYS 790  
1565 1 Y 1 A THR 791  ? C THR 791  
1566 1 Y 1 A PRO 792  ? C PRO 792  
1567 1 Y 1 A PRO 793  ? C PRO 793  
1568 1 Y 1 A ILE 794  ? C ILE 794  
1569 1 Y 1 A LYS 795  ? C LYS 795  
1570 1 Y 1 A ASP 796  ? C ASP 796  
1571 1 Y 1 A PHE 797  ? C PHE 797  
1572 1 Y 1 A GLY 798  ? C GLY 798  
1573 1 Y 1 A GLY 799  ? C GLY 799  
1574 1 Y 1 A PHE 800  ? C PHE 800  
1575 1 Y 1 A ASN 801  ? C ASN 801  
1576 1 Y 1 A PHE 802  ? C PHE 802  
1577 1 Y 1 A SER 803  ? C SER 803  
1578 1 Y 1 A GLN 804  ? C GLN 804  
1579 1 Y 1 A ILE 805  ? C ILE 805  
1580 1 Y 1 A LEU 806  ? C LEU 806  
1581 1 Y 1 A PRO 807  ? C PRO 807  
1582 1 Y 1 A ASP 808  ? C ASP 808  
1583 1 Y 1 A PRO 809  ? C PRO 809  
1584 1 Y 1 A SER 810  ? C SER 810  
1585 1 Y 1 A LYS 811  ? C LYS 811  
1586 1 Y 1 A PRO 812  ? C PRO 812  
1587 1 Y 1 A SER 813  ? C SER 813  
1588 1 Y 1 A LYS 814  ? C LYS 814  
1589 1 Y 1 A ARG 815  ? C ARG 815  
1590 1 Y 1 A SER 816  ? C SER 816  
1591 1 Y 1 A PHE 817  ? C PHE 817  
1592 1 Y 1 A ILE 818  ? C ILE 818  
1593 1 Y 1 A GLU 819  ? C GLU 819  
1594 1 Y 1 A ASP 820  ? C ASP 820  
1595 1 Y 1 A LEU 821  ? C LEU 821  
1596 1 Y 1 A LEU 822  ? C LEU 822  
1597 1 Y 1 A PHE 823  ? C PHE 823  
1598 1 Y 1 A ASN 824  ? C ASN 824  
1599 1 Y 1 A LYS 825  ? C LYS 825  
1600 1 Y 1 A VAL 826  ? C VAL 826  
1601 1 Y 1 A THR 827  ? C THR 827  
1602 1 Y 1 A LEU 828  ? C LEU 828  
1603 1 Y 1 A ALA 829  ? C ALA 829  
1604 1 Y 1 A ASP 830  ? C ASP 830  
1605 1 Y 1 A ALA 831  ? C ALA 831  
1606 1 Y 1 A GLY 832  ? C GLY 832  
1607 1 Y 1 A PHE 833  ? C PHE 833  
1608 1 Y 1 A ILE 834  ? C ILE 834  
1609 1 Y 1 A LYS 835  ? C LYS 835  
1610 1 Y 1 A GLN 836  ? C GLN 836  
1611 1 Y 1 A TYR 837  ? C TYR 837  
1612 1 Y 1 A GLY 838  ? C GLY 838  
1613 1 Y 1 A ASP 839  ? C ASP 839  
1614 1 Y 1 A CYS 840  ? C CYS 840  
1615 1 Y 1 A LEU 841  ? C LEU 841  
1616 1 Y 1 A GLY 842  ? C GLY 842  
1617 1 Y 1 A ASP 843  ? C ASP 843  
1618 1 Y 1 A ILE 844  ? C ILE 844  
1619 1 Y 1 A ALA 845  ? C ALA 845  
1620 1 Y 1 A ALA 846  ? C ALA 846  
1621 1 Y 1 A ARG 847  ? C ARG 847  
1622 1 Y 1 A ASP 848  ? C ASP 848  
1623 1 Y 1 A LEU 849  ? C LEU 849  
1624 1 Y 1 A ILE 850  ? C ILE 850  
1625 1 Y 1 A CYS 851  ? C CYS 851  
1626 1 Y 1 A ALA 852  ? C ALA 852  
1627 1 Y 1 A GLN 853  ? C GLN 853  
1628 1 Y 1 A LYS 854  ? C LYS 854  
1629 1 Y 1 A PHE 855  ? C PHE 855  
1630 1 Y 1 A ASN 856  ? C ASN 856  
1631 1 Y 1 A GLY 857  ? C GLY 857  
1632 1 Y 1 A LEU 858  ? C LEU 858  
1633 1 Y 1 A THR 859  ? C THR 859  
1634 1 Y 1 A VAL 860  ? C VAL 860  
1635 1 Y 1 A LEU 861  ? C LEU 861  
1636 1 Y 1 A PRO 862  ? C PRO 862  
1637 1 Y 1 A PRO 863  ? C PRO 863  
1638 1 Y 1 A LEU 864  ? C LEU 864  
1639 1 Y 1 A LEU 865  ? C LEU 865  
1640 1 Y 1 A THR 866  ? C THR 866  
1641 1 Y 1 A ASP 867  ? C ASP 867  
1642 1 Y 1 A GLU 868  ? C GLU 868  
1643 1 Y 1 A MET 869  ? C MET 869  
1644 1 Y 1 A ILE 870  ? C ILE 870  
1645 1 Y 1 A ALA 871  ? C ALA 871  
1646 1 Y 1 A GLN 872  ? C GLN 872  
1647 1 Y 1 A TYR 873  ? C TYR 873  
1648 1 Y 1 A THR 874  ? C THR 874  
1649 1 Y 1 A SER 875  ? C SER 875  
1650 1 Y 1 A ALA 876  ? C ALA 876  
1651 1 Y 1 A LEU 877  ? C LEU 877  
1652 1 Y 1 A LEU 878  ? C LEU 878  
1653 1 Y 1 A ALA 879  ? C ALA 879  
1654 1 Y 1 A GLY 880  ? C GLY 880  
1655 1 Y 1 A THR 881  ? C THR 881  
1656 1 Y 1 A ILE 882  ? C ILE 882  
1657 1 Y 1 A THR 883  ? C THR 883  
1658 1 Y 1 A SER 884  ? C SER 884  
1659 1 Y 1 A GLY 885  ? C GLY 885  
1660 1 Y 1 A TRP 886  ? C TRP 886  
1661 1 Y 1 A THR 887  ? C THR 887  
1662 1 Y 1 A PHE 888  ? C PHE 888  
1663 1 Y 1 A GLY 889  ? C GLY 889  
1664 1 Y 1 A ALA 890  ? C ALA 890  
1665 1 Y 1 A GLY 891  ? C GLY 891  
1666 1 Y 1 A ALA 892  ? C ALA 892  
1667 1 Y 1 A ALA 893  ? C ALA 893  
1668 1 Y 1 A LEU 894  ? C LEU 894  
1669 1 Y 1 A GLN 895  ? C GLN 895  
1670 1 Y 1 A ILE 896  ? C ILE 896  
1671 1 Y 1 A PRO 897  ? C PRO 897  
1672 1 Y 1 A PHE 898  ? C PHE 898  
1673 1 Y 1 A ALA 899  ? C ALA 899  
1674 1 Y 1 A MET 900  ? C MET 900  
1675 1 Y 1 A GLN 901  ? C GLN 901  
1676 1 Y 1 A MET 902  ? C MET 902  
1677 1 Y 1 A ALA 903  ? C ALA 903  
1678 1 Y 1 A TYR 904  ? C TYR 904  
1679 1 Y 1 A ARG 905  ? C ARG 905  
1680 1 Y 1 A PHE 906  ? C PHE 906  
1681 1 Y 1 A ASN 907  ? C ASN 907  
1682 1 Y 1 A GLY 908  ? C GLY 908  
1683 1 Y 1 A ILE 909  ? C ILE 909  
1684 1 Y 1 A GLY 910  ? C GLY 910  
1685 1 Y 1 A VAL 911  ? C VAL 911  
1686 1 Y 1 A THR 912  ? C THR 912  
1687 1 Y 1 A GLN 913  ? C GLN 913  
1688 1 Y 1 A ASN 914  ? C ASN 914  
1689 1 Y 1 A VAL 915  ? C VAL 915  
1690 1 Y 1 A LEU 916  ? C LEU 916  
1691 1 Y 1 A TYR 917  ? C TYR 917  
1692 1 Y 1 A GLU 918  ? C GLU 918  
1693 1 Y 1 A ASN 919  ? C ASN 919  
1694 1 Y 1 A GLN 920  ? C GLN 920  
1695 1 Y 1 A LYS 921  ? C LYS 921  
1696 1 Y 1 A LEU 922  ? C LEU 922  
1697 1 Y 1 A ILE 923  ? C ILE 923  
1698 1 Y 1 A ALA 924  ? C ALA 924  
1699 1 Y 1 A ASN 925  ? C ASN 925  
1700 1 Y 1 A GLN 926  ? C GLN 926  
1701 1 Y 1 A PHE 927  ? C PHE 927  
1702 1 Y 1 A ASN 928  ? C ASN 928  
1703 1 Y 1 A SER 929  ? C SER 929  
1704 1 Y 1 A ALA 930  ? C ALA 930  
1705 1 Y 1 A ILE 931  ? C ILE 931  
1706 1 Y 1 A GLY 932  ? C GLY 932  
1707 1 Y 1 A LYS 933  ? C LYS 933  
1708 1 Y 1 A ILE 934  ? C ILE 934  
1709 1 Y 1 A GLN 935  ? C GLN 935  
1710 1 Y 1 A ASP 936  ? C ASP 936  
1711 1 Y 1 A SER 937  ? C SER 937  
1712 1 Y 1 A LEU 938  ? C LEU 938  
1713 1 Y 1 A SER 939  ? C SER 939  
1714 1 Y 1 A SER 940  ? C SER 940  
1715 1 Y 1 A THR 941  ? C THR 941  
1716 1 Y 1 A ALA 942  ? C ALA 942  
1717 1 Y 1 A SER 943  ? C SER 943  
1718 1 Y 1 A ALA 944  ? C ALA 944  
1719 1 Y 1 A LEU 945  ? C LEU 945  
1720 1 Y 1 A GLY 946  ? C GLY 946  
1721 1 Y 1 A LYS 947  ? C LYS 947  
1722 1 Y 1 A LEU 948  ? C LEU 948  
1723 1 Y 1 A GLN 949  ? C GLN 949  
1724 1 Y 1 A ASP 950  ? C ASP 950  
1725 1 Y 1 A VAL 951  ? C VAL 951  
1726 1 Y 1 A VAL 952  ? C VAL 952  
1727 1 Y 1 A ASN 953  ? C ASN 953  
1728 1 Y 1 A GLN 954  ? C GLN 954  
1729 1 Y 1 A ASN 955  ? C ASN 955  
1730 1 Y 1 A ALA 956  ? C ALA 956  
1731 1 Y 1 A GLN 957  ? C GLN 957  
1732 1 Y 1 A ALA 958  ? C ALA 958  
1733 1 Y 1 A LEU 959  ? C LEU 959  
1734 1 Y 1 A ASN 960  ? C ASN 960  
1735 1 Y 1 A THR 961  ? C THR 961  
1736 1 Y 1 A LEU 962  ? C LEU 962  
1737 1 Y 1 A VAL 963  ? C VAL 963  
1738 1 Y 1 A LYS 964  ? C LYS 964  
1739 1 Y 1 A GLN 965  ? C GLN 965  
1740 1 Y 1 A LEU 966  ? C LEU 966  
1741 1 Y 1 A SER 967  ? C SER 967  
1742 1 Y 1 A SER 968  ? C SER 968  
1743 1 Y 1 A ASN 969  ? C ASN 969  
1744 1 Y 1 A PHE 970  ? C PHE 970  
1745 1 Y 1 A GLY 971  ? C GLY 971  
1746 1 Y 1 A ALA 972  ? C ALA 972  
1747 1 Y 1 A ILE 973  ? C ILE 973  
1748 1 Y 1 A SER 974  ? C SER 974  
1749 1 Y 1 A SER 975  ? C SER 975  
1750 1 Y 1 A VAL 976  ? C VAL 976  
1751 1 Y 1 A LEU 977  ? C LEU 977  
1752 1 Y 1 A ASN 978  ? C ASN 978  
1753 1 Y 1 A ASP 979  ? C ASP 979  
1754 1 Y 1 A ILE 980  ? C ILE 980  
1755 1 Y 1 A LEU 981  ? C LEU 981  
1756 1 Y 1 A SER 982  ? C SER 982  
1757 1 Y 1 A ARG 983  ? C ARG 983  
1758 1 Y 1 A LEU 984  ? C LEU 984  
1759 1 Y 1 A ASP 985  ? C ASP 985  
1760 1 Y 1 A LYS 986  ? C LYS 986  
1761 1 Y 1 A VAL 987  ? C VAL 987  
1762 1 Y 1 A GLU 988  ? C GLU 988  
1763 1 Y 1 A ALA 989  ? C ALA 989  
1764 1 Y 1 A GLU 990  ? C GLU 990  
1765 1 Y 1 A VAL 991  ? C VAL 991  
1766 1 Y 1 A GLN 992  ? C GLN 992  
1767 1 Y 1 A ILE 993  ? C ILE 993  
1768 1 Y 1 A ASP 994  ? C ASP 994  
1769 1 Y 1 A ARG 995  ? C ARG 995  
1770 1 Y 1 A LEU 996  ? C LEU 996  
1771 1 Y 1 A ILE 997  ? C ILE 997  
1772 1 Y 1 A THR 998  ? C THR 998  
1773 1 Y 1 A GLY 999  ? C GLY 999  
1774 1 Y 1 A ARG 1000 ? C ARG 1000 
1775 1 Y 1 A LEU 1001 ? C LEU 1001 
1776 1 Y 1 A GLN 1002 ? C GLN 1002 
1777 1 Y 1 A SER 1003 ? C SER 1003 
1778 1 Y 1 A LEU 1004 ? C LEU 1004 
1779 1 Y 1 A GLN 1005 ? C GLN 1005 
1780 1 Y 1 A THR 1006 ? C THR 1006 
1781 1 Y 1 A TYR 1007 ? C TYR 1007 
1782 1 Y 1 A VAL 1008 ? C VAL 1008 
1783 1 Y 1 A THR 1009 ? C THR 1009 
1784 1 Y 1 A GLN 1010 ? C GLN 1010 
1785 1 Y 1 A GLN 1011 ? C GLN 1011 
1786 1 Y 1 A LEU 1012 ? C LEU 1012 
1787 1 Y 1 A ILE 1013 ? C ILE 1013 
1788 1 Y 1 A ARG 1014 ? C ARG 1014 
1789 1 Y 1 A ALA 1015 ? C ALA 1015 
1790 1 Y 1 A ALA 1016 ? C ALA 1016 
1791 1 Y 1 A GLU 1017 ? C GLU 1017 
1792 1 Y 1 A ILE 1018 ? C ILE 1018 
1793 1 Y 1 A ARG 1019 ? C ARG 1019 
1794 1 Y 1 A ALA 1020 ? C ALA 1020 
1795 1 Y 1 A SER 1021 ? C SER 1021 
1796 1 Y 1 A ALA 1022 ? C ALA 1022 
1797 1 Y 1 A ASN 1023 ? C ASN 1023 
1798 1 Y 1 A LEU 1024 ? C LEU 1024 
1799 1 Y 1 A ALA 1025 ? C ALA 1025 
1800 1 Y 1 A ALA 1026 ? C ALA 1026 
1801 1 Y 1 A THR 1027 ? C THR 1027 
1802 1 Y 1 A LYS 1028 ? C LYS 1028 
1803 1 Y 1 A MET 1029 ? C MET 1029 
1804 1 Y 1 A SER 1030 ? C SER 1030 
1805 1 Y 1 A GLU 1031 ? C GLU 1031 
1806 1 Y 1 A CYS 1032 ? C CYS 1032 
1807 1 Y 1 A VAL 1033 ? C VAL 1033 
1808 1 Y 1 A LEU 1034 ? C LEU 1034 
1809 1 Y 1 A GLY 1035 ? C GLY 1035 
1810 1 Y 1 A GLN 1036 ? C GLN 1036 
1811 1 Y 1 A SER 1037 ? C SER 1037 
1812 1 Y 1 A LYS 1038 ? C LYS 1038 
1813 1 Y 1 A ARG 1039 ? C ARG 1039 
1814 1 Y 1 A VAL 1040 ? C VAL 1040 
1815 1 Y 1 A ASP 1041 ? C ASP 1041 
1816 1 Y 1 A PHE 1042 ? C PHE 1042 
1817 1 Y 1 A CYS 1043 ? C CYS 1043 
1818 1 Y 1 A GLY 1044 ? C GLY 1044 
1819 1 Y 1 A LYS 1045 ? C LYS 1045 
1820 1 Y 1 A GLY 1046 ? C GLY 1046 
1821 1 Y 1 A TYR 1047 ? C TYR 1047 
1822 1 Y 1 A HIS 1048 ? C HIS 1048 
1823 1 Y 1 A LEU 1049 ? C LEU 1049 
1824 1 Y 1 A MET 1050 ? C MET 1050 
1825 1 Y 1 A SER 1051 ? C SER 1051 
1826 1 Y 1 A PHE 1052 ? C PHE 1052 
1827 1 Y 1 A PRO 1053 ? C PRO 1053 
1828 1 Y 1 A GLN 1054 ? C GLN 1054 
1829 1 Y 1 A SER 1055 ? C SER 1055 
1830 1 Y 1 A ALA 1056 ? C ALA 1056 
1831 1 Y 1 A PRO 1057 ? C PRO 1057 
1832 1 Y 1 A HIS 1058 ? C HIS 1058 
1833 1 Y 1 A GLY 1059 ? C GLY 1059 
1834 1 Y 1 A VAL 1060 ? C VAL 1060 
1835 1 Y 1 A VAL 1061 ? C VAL 1061 
1836 1 Y 1 A PHE 1062 ? C PHE 1062 
1837 1 Y 1 A LEU 1063 ? C LEU 1063 
1838 1 Y 1 A HIS 1064 ? C HIS 1064 
1839 1 Y 1 A VAL 1065 ? C VAL 1065 
1840 1 Y 1 A THR 1066 ? C THR 1066 
1841 1 Y 1 A TYR 1067 ? C TYR 1067 
1842 1 Y 1 A VAL 1068 ? C VAL 1068 
1843 1 Y 1 A PRO 1069 ? C PRO 1069 
1844 1 Y 1 A ALA 1070 ? C ALA 1070 
1845 1 Y 1 A GLN 1071 ? C GLN 1071 
1846 1 Y 1 A GLU 1072 ? C GLU 1072 
1847 1 Y 1 A LYS 1073 ? C LYS 1073 
1848 1 Y 1 A ASN 1074 ? C ASN 1074 
1849 1 Y 1 A PHE 1075 ? C PHE 1075 
1850 1 Y 1 A THR 1076 ? C THR 1076 
1851 1 Y 1 A THR 1077 ? C THR 1077 
1852 1 Y 1 A ALA 1078 ? C ALA 1078 
1853 1 Y 1 A PRO 1079 ? C PRO 1079 
1854 1 Y 1 A ALA 1080 ? C ALA 1080 
1855 1 Y 1 A ILE 1081 ? C ILE 1081 
1856 1 Y 1 A CYS 1082 ? C CYS 1082 
1857 1 Y 1 A HIS 1083 ? C HIS 1083 
1858 1 Y 1 A ASP 1084 ? C ASP 1084 
1859 1 Y 1 A GLY 1085 ? C GLY 1085 
1860 1 Y 1 A LYS 1086 ? C LYS 1086 
1861 1 Y 1 A ALA 1087 ? C ALA 1087 
1862 1 Y 1 A HIS 1088 ? C HIS 1088 
1863 1 Y 1 A PHE 1089 ? C PHE 1089 
1864 1 Y 1 A PRO 1090 ? C PRO 1090 
1865 1 Y 1 A ARG 1091 ? C ARG 1091 
1866 1 Y 1 A GLU 1092 ? C GLU 1092 
1867 1 Y 1 A GLY 1093 ? C GLY 1093 
1868 1 Y 1 A VAL 1094 ? C VAL 1094 
1869 1 Y 1 A PHE 1095 ? C PHE 1095 
1870 1 Y 1 A VAL 1096 ? C VAL 1096 
1871 1 Y 1 A SER 1097 ? C SER 1097 
1872 1 Y 1 A ASN 1098 ? C ASN 1098 
1873 1 Y 1 A GLY 1099 ? C GLY 1099 
1874 1 Y 1 A THR 1100 ? C THR 1100 
1875 1 Y 1 A HIS 1101 ? C HIS 1101 
1876 1 Y 1 A TRP 1102 ? C TRP 1102 
1877 1 Y 1 A PHE 1103 ? C PHE 1103 
1878 1 Y 1 A VAL 1104 ? C VAL 1104 
1879 1 Y 1 A THR 1105 ? C THR 1105 
1880 1 Y 1 A GLN 1106 ? C GLN 1106 
1881 1 Y 1 A ARG 1107 ? C ARG 1107 
1882 1 Y 1 A ASN 1108 ? C ASN 1108 
1883 1 Y 1 A PHE 1109 ? C PHE 1109 
1884 1 Y 1 A TYR 1110 ? C TYR 1110 
1885 1 Y 1 A GLU 1111 ? C GLU 1111 
1886 1 Y 1 A PRO 1112 ? C PRO 1112 
1887 1 Y 1 A GLN 1113 ? C GLN 1113 
1888 1 Y 1 A ILE 1114 ? C ILE 1114 
1889 1 Y 1 A ILE 1115 ? C ILE 1115 
1890 1 Y 1 A THR 1116 ? C THR 1116 
1891 1 Y 1 A THR 1117 ? C THR 1117 
1892 1 Y 1 A ASP 1118 ? C ASP 1118 
1893 1 Y 1 A ASN 1119 ? C ASN 1119 
1894 1 Y 1 A THR 1120 ? C THR 1120 
1895 1 Y 1 A PHE 1121 ? C PHE 1121 
1896 1 Y 1 A VAL 1122 ? C VAL 1122 
1897 1 Y 1 A SER 1123 ? C SER 1123 
1898 1 Y 1 A GLY 1124 ? C GLY 1124 
1899 1 Y 1 A ASN 1125 ? C ASN 1125 
1900 1 Y 1 A CYS 1126 ? C CYS 1126 
1901 1 Y 1 A ASP 1127 ? C ASP 1127 
1902 1 Y 1 A VAL 1128 ? C VAL 1128 
1903 1 Y 1 A VAL 1129 ? C VAL 1129 
1904 1 Y 1 A ILE 1130 ? C ILE 1130 
1905 1 Y 1 A GLY 1131 ? C GLY 1131 
1906 1 Y 1 A ILE 1132 ? C ILE 1132 
1907 1 Y 1 A VAL 1133 ? C VAL 1133 
1908 1 Y 1 A ASN 1134 ? C ASN 1134 
1909 1 Y 1 A ASN 1135 ? C ASN 1135 
1910 1 Y 1 A THR 1136 ? C THR 1136 
1911 1 Y 1 A VAL 1137 ? C VAL 1137 
1912 1 Y 1 A TYR 1138 ? C TYR 1138 
1913 1 Y 1 A ASP 1139 ? C ASP 1139 
1914 1 Y 1 A PRO 1140 ? C PRO 1140 
1915 1 Y 1 A LEU 1141 ? C LEU 1141 
1916 1 Y 1 A GLN 1142 ? C GLN 1142 
1917 1 Y 1 A PRO 1143 ? C PRO 1143 
1918 1 Y 1 A GLU 1144 ? C GLU 1144 
1919 1 Y 1 A LEU 1145 ? C LEU 1145 
1920 1 Y 1 A ASP 1146 ? C ASP 1146 
1921 1 Y 1 A SER 1147 ? C SER 1147 
1922 1 Y 1 A PHE 1148 ? C PHE 1148 
1923 1 Y 1 A LYS 1149 ? C LYS 1149 
1924 1 Y 1 A GLU 1150 ? C GLU 1150 
1925 1 Y 1 A GLU 1151 ? C GLU 1151 
1926 1 Y 1 A LEU 1152 ? C LEU 1152 
1927 1 Y 1 A ASP 1153 ? C ASP 1153 
1928 1 Y 1 A LYS 1154 ? C LYS 1154 
1929 1 Y 1 A TYR 1155 ? C TYR 1155 
1930 1 Y 1 A PHE 1156 ? C PHE 1156 
1931 1 Y 1 A LYS 1157 ? C LYS 1157 
1932 1 Y 1 A ASN 1158 ? C ASN 1158 
1933 1 Y 1 A HIS 1159 ? C HIS 1159 
1934 1 Y 1 A THR 1160 ? C THR 1160 
1935 1 Y 1 A SER 1161 ? C SER 1161 
1936 1 Y 1 A PRO 1162 ? C PRO 1162 
1937 1 Y 1 A ASP 1163 ? C ASP 1163 
1938 1 Y 1 A VAL 1164 ? C VAL 1164 
1939 1 Y 1 A ASP 1165 ? C ASP 1165 
1940 1 Y 1 A LEU 1166 ? C LEU 1166 
1941 1 Y 1 A GLY 1167 ? C GLY 1167 
1942 1 Y 1 A ASP 1168 ? C ASP 1168 
1943 1 Y 1 A ILE 1169 ? C ILE 1169 
1944 1 Y 1 A SER 1170 ? C SER 1170 
1945 1 Y 1 A GLY 1171 ? C GLY 1171 
1946 1 Y 1 A ILE 1172 ? C ILE 1172 
1947 1 Y 1 A ASN 1173 ? C ASN 1173 
1948 1 Y 1 A ALA 1174 ? C ALA 1174 
1949 1 Y 1 A SER 1175 ? C SER 1175 
1950 1 Y 1 A VAL 1176 ? C VAL 1176 
1951 1 Y 1 A VAL 1177 ? C VAL 1177 
1952 1 Y 1 A ASN 1178 ? C ASN 1178 
1953 1 Y 1 A ILE 1179 ? C ILE 1179 
1954 1 Y 1 A GLN 1180 ? C GLN 1180 
1955 1 Y 1 A LYS 1181 ? C LYS 1181 
1956 1 Y 1 A GLU 1182 ? C GLU 1182 
1957 1 Y 1 A ILE 1183 ? C ILE 1183 
1958 1 Y 1 A ASP 1184 ? C ASP 1184 
1959 1 Y 1 A ARG 1185 ? C ARG 1185 
1960 1 Y 1 A LEU 1186 ? C LEU 1186 
1961 1 Y 1 A ASN 1187 ? C ASN 1187 
1962 1 Y 1 A GLU 1188 ? C GLU 1188 
1963 1 Y 1 A VAL 1189 ? C VAL 1189 
1964 1 Y 1 A ALA 1190 ? C ALA 1190 
1965 1 Y 1 A LYS 1191 ? C LYS 1191 
1966 1 Y 1 A ASN 1192 ? C ASN 1192 
1967 1 Y 1 A LEU 1193 ? C LEU 1193 
1968 1 Y 1 A ASN 1194 ? C ASN 1194 
1969 1 Y 1 A GLU 1195 ? C GLU 1195 
1970 1 Y 1 A SER 1196 ? C SER 1196 
1971 1 Y 1 A LEU 1197 ? C LEU 1197 
1972 1 Y 1 A ILE 1198 ? C ILE 1198 
1973 1 Y 1 A ASP 1199 ? C ASP 1199 
1974 1 Y 1 A LEU 1200 ? C LEU 1200 
1975 1 Y 1 A GLN 1201 ? C GLN 1201 
1976 1 Y 1 A GLU 1202 ? C GLU 1202 
1977 1 Y 1 A LEU 1203 ? C LEU 1203 
1978 1 Y 1 A GLY 1204 ? C GLY 1204 
1979 1 Y 1 A LYS 1205 ? C LYS 1205 
1980 1 Y 1 A TYR 1206 ? C TYR 1206 
1981 1 Y 1 A GLU 1207 ? C GLU 1207 
1982 1 Y 1 A GLN 1208 ? C GLN 1208 
1983 1 Y 1 A GLY 1209 ? C GLY 1209 
1984 1 Y 1 A SER 1210 ? C SER 1210 
1985 1 Y 1 A GLY 1211 ? C GLY 1211 
1986 1 Y 1 A TYR 1212 ? C TYR 1212 
1987 1 Y 1 A ILE 1213 ? C ILE 1213 
1988 1 Y 1 A PRO 1214 ? C PRO 1214 
1989 1 Y 1 A GLU 1215 ? C GLU 1215 
1990 1 Y 1 A ALA 1216 ? C ALA 1216 
1991 1 Y 1 A PRO 1217 ? C PRO 1217 
1992 1 Y 1 A ARG 1218 ? C ARG 1218 
1993 1 Y 1 A ASP 1219 ? C ASP 1219 
1994 1 Y 1 A GLY 1220 ? C GLY 1220 
1995 1 Y 1 A GLN 1221 ? C GLN 1221 
1996 1 Y 1 A ALA 1222 ? C ALA 1222 
1997 1 Y 1 A TYR 1223 ? C TYR 1223 
1998 1 Y 1 A VAL 1224 ? C VAL 1224 
1999 1 Y 1 A ARG 1225 ? C ARG 1225 
2000 1 Y 1 A LYS 1226 ? C LYS 1226 
2001 1 Y 1 A ASP 1227 ? C ASP 1227 
2002 1 Y 1 A GLY 1228 ? C GLY 1228 
2003 1 Y 1 A GLU 1229 ? C GLU 1229 
2004 1 Y 1 A TRP 1230 ? C TRP 1230 
2005 1 Y 1 A VAL 1231 ? C VAL 1231 
2006 1 Y 1 A PHE 1232 ? C PHE 1232 
2007 1 Y 1 A LEU 1233 ? C LEU 1233 
2008 1 Y 1 A SER 1234 ? C SER 1234 
2009 1 Y 1 A THR 1235 ? C THR 1235 
2010 1 Y 1 A PHE 1236 ? C PHE 1236 
2011 1 Y 1 A LEU 1237 ? C LEU 1237 
2012 1 Y 1 A SER 1238 ? C SER 1238 
2013 1 Y 1 A GLY 1239 ? C GLY 1239 
2014 1 Y 1 A LEU 1240 ? C LEU 1240 
2015 1 Y 1 A GLU 1241 ? C GLU 1241 
2016 1 Y 1 A VAL 1242 ? C VAL 1242 
2017 1 Y 1 A LEU 1243 ? C LEU 1243 
2018 1 Y 1 A PHE 1244 ? C PHE 1244 
2019 1 Y 1 A GLN 1245 ? C GLN 1245 
2020 1 Y 1 A GLY 1246 ? C GLY 1246 
2021 1 Y 1 A PRO 1247 ? C PRO 1247 
2022 1 Y 1 A GLY 1248 ? C GLY 1248 
2023 1 Y 1 A GLY 1249 ? C GLY 1249 
2024 1 Y 1 A TRP 1250 ? C TRP 1250 
2025 1 Y 1 A SER 1251 ? C SER 1251 
2026 1 Y 1 A HIS 1252 ? C HIS 1252 
2027 1 Y 1 A PRO 1253 ? C PRO 1253 
2028 1 Y 1 A GLN 1254 ? C GLN 1254 
2029 1 Y 1 A PHE 1255 ? C PHE 1255 
2030 1 Y 1 A GLU 1256 ? C GLU 1256 
2031 1 Y 1 A LYS 1257 ? C LYS 1257 
2032 1 Y 1 A GLY 1258 ? C GLY 1258 
2033 1 Y 1 A GLY 1259 ? C GLY 1259 
2034 1 Y 1 A GLY 1260 ? C GLY 1260 
2035 1 Y 1 A SER 1261 ? C SER 1261 
2036 1 Y 1 A GLY 1262 ? C GLY 1262 
2037 1 Y 1 A GLY 1263 ? C GLY 1263 
2038 1 Y 1 A GLY 1264 ? C GLY 1264 
2039 1 Y 1 A SER 1265 ? C SER 1265 
2040 1 Y 1 A GLY 1266 ? C GLY 1266 
2041 1 Y 1 A GLY 1267 ? C GLY 1267 
2042 1 Y 1 A SER 1268 ? C SER 1268 
2043 1 Y 1 A ALA 1269 ? C ALA 1269 
2044 1 Y 1 A TRP 1270 ? C TRP 1270 
2045 1 Y 1 A SER 1271 ? C SER 1271 
2046 1 Y 1 A HIS 1272 ? C HIS 1272 
2047 1 Y 1 A PRO 1273 ? C PRO 1273 
2048 1 Y 1 A GLN 1274 ? C GLN 1274 
2049 1 Y 1 A PHE 1275 ? C PHE 1275 
2050 1 Y 1 A GLU 1276 ? C GLU 1276 
2051 1 Y 1 A LYS 1277 ? C LYS 1277 
2052 1 Y 1 A GLY 1278 ? C GLY 1278 
2053 1 Y 1 A GLY 1279 ? C GLY 1279 
2054 1 Y 1 A SER 1280 ? C SER 1280 
2055 1 Y 1 A HIS 1281 ? C HIS 1281 
2056 1 Y 1 A HIS 1282 ? C HIS 1282 
2057 1 Y 1 A HIS 1283 ? C HIS 1283 
2058 1 Y 1 A HIS 1284 ? C HIS 1284 
2059 1 Y 1 A HIS 1285 ? C HIS 1285 
2060 1 Y 1 A HIS 1286 ? C HIS 1286 
2061 1 Y 1 A HIS 1287 ? C HIS 1287 
2062 1 Y 1 A HIS 1288 ? C HIS 1288 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
BMA C1   C N R 74  
BMA C2   C N S 75  
BMA C3   C N S 76  
BMA C4   C N S 77  
BMA C5   C N R 78  
BMA C6   C N N 79  
BMA O1   O N N 80  
BMA O2   O N N 81  
BMA O3   O N N 82  
BMA O4   O N N 83  
BMA O5   O N N 84  
BMA O6   O N N 85  
BMA H1   H N N 86  
BMA H2   H N N 87  
BMA H3   H N N 88  
BMA H4   H N N 89  
BMA H5   H N N 90  
BMA H61  H N N 91  
BMA H62  H N N 92  
BMA HO1  H N N 93  
BMA HO2  H N N 94  
BMA HO3  H N N 95  
BMA HO4  H N N 96  
BMA HO6  H N N 97  
CYS N    N N N 98  
CYS CA   C N R 99  
CYS C    C N N 100 
CYS O    O N N 101 
CYS CB   C N N 102 
CYS SG   S N N 103 
CYS OXT  O N N 104 
CYS H    H N N 105 
CYS H2   H N N 106 
CYS HA   H N N 107 
CYS HB2  H N N 108 
CYS HB3  H N N 109 
CYS HG   H N N 110 
CYS HXT  H N N 111 
GLN N    N N N 112 
GLN CA   C N S 113 
GLN C    C N N 114 
GLN O    O N N 115 
GLN CB   C N N 116 
GLN CG   C N N 117 
GLN CD   C N N 118 
GLN OE1  O N N 119 
GLN NE2  N N N 120 
GLN OXT  O N N 121 
GLN H    H N N 122 
GLN H2   H N N 123 
GLN HA   H N N 124 
GLN HB2  H N N 125 
GLN HB3  H N N 126 
GLN HG2  H N N 127 
GLN HG3  H N N 128 
GLN HE21 H N N 129 
GLN HE22 H N N 130 
GLN HXT  H N N 131 
GLU N    N N N 132 
GLU CA   C N S 133 
GLU C    C N N 134 
GLU O    O N N 135 
GLU CB   C N N 136 
GLU CG   C N N 137 
GLU CD   C N N 138 
GLU OE1  O N N 139 
GLU OE2  O N N 140 
GLU OXT  O N N 141 
GLU H    H N N 142 
GLU H2   H N N 143 
GLU HA   H N N 144 
GLU HB2  H N N 145 
GLU HB3  H N N 146 
GLU HG2  H N N 147 
GLU HG3  H N N 148 
GLU HE2  H N N 149 
GLU HXT  H N N 150 
GLY N    N N N 151 
GLY CA   C N N 152 
GLY C    C N N 153 
GLY O    O N N 154 
GLY OXT  O N N 155 
GLY H    H N N 156 
GLY H2   H N N 157 
GLY HA2  H N N 158 
GLY HA3  H N N 159 
GLY HXT  H N N 160 
HIS N    N N N 161 
HIS CA   C N S 162 
HIS C    C N N 163 
HIS O    O N N 164 
HIS CB   C N N 165 
HIS CG   C Y N 166 
HIS ND1  N Y N 167 
HIS CD2  C Y N 168 
HIS CE1  C Y N 169 
HIS NE2  N Y N 170 
HIS OXT  O N N 171 
HIS H    H N N 172 
HIS H2   H N N 173 
HIS HA   H N N 174 
HIS HB2  H N N 175 
HIS HB3  H N N 176 
HIS HD1  H N N 177 
HIS HD2  H N N 178 
HIS HE1  H N N 179 
HIS HE2  H N N 180 
HIS HXT  H N N 181 
ILE N    N N N 182 
ILE CA   C N S 183 
ILE C    C N N 184 
ILE O    O N N 185 
ILE CB   C N S 186 
ILE CG1  C N N 187 
ILE CG2  C N N 188 
ILE CD1  C N N 189 
ILE OXT  O N N 190 
ILE H    H N N 191 
ILE H2   H N N 192 
ILE HA   H N N 193 
ILE HB   H N N 194 
ILE HG12 H N N 195 
ILE HG13 H N N 196 
ILE HG21 H N N 197 
ILE HG22 H N N 198 
ILE HG23 H N N 199 
ILE HD11 H N N 200 
ILE HD12 H N N 201 
ILE HD13 H N N 202 
ILE HXT  H N N 203 
LEU N    N N N 204 
LEU CA   C N S 205 
LEU C    C N N 206 
LEU O    O N N 207 
LEU CB   C N N 208 
LEU CG   C N N 209 
LEU CD1  C N N 210 
LEU CD2  C N N 211 
LEU OXT  O N N 212 
LEU H    H N N 213 
LEU H2   H N N 214 
LEU HA   H N N 215 
LEU HB2  H N N 216 
LEU HB3  H N N 217 
LEU HG   H N N 218 
LEU HD11 H N N 219 
LEU HD12 H N N 220 
LEU HD13 H N N 221 
LEU HD21 H N N 222 
LEU HD22 H N N 223 
LEU HD23 H N N 224 
LEU HXT  H N N 225 
LYS N    N N N 226 
LYS CA   C N S 227 
LYS C    C N N 228 
LYS O    O N N 229 
LYS CB   C N N 230 
LYS CG   C N N 231 
LYS CD   C N N 232 
LYS CE   C N N 233 
LYS NZ   N N N 234 
LYS OXT  O N N 235 
LYS H    H N N 236 
LYS H2   H N N 237 
LYS HA   H N N 238 
LYS HB2  H N N 239 
LYS HB3  H N N 240 
LYS HG2  H N N 241 
LYS HG3  H N N 242 
LYS HD2  H N N 243 
LYS HD3  H N N 244 
LYS HE2  H N N 245 
LYS HE3  H N N 246 
LYS HZ1  H N N 247 
LYS HZ2  H N N 248 
LYS HZ3  H N N 249 
LYS HXT  H N N 250 
MET N    N N N 251 
MET CA   C N S 252 
MET C    C N N 253 
MET O    O N N 254 
MET CB   C N N 255 
MET CG   C N N 256 
MET SD   S N N 257 
MET CE   C N N 258 
MET OXT  O N N 259 
MET H    H N N 260 
MET H2   H N N 261 
MET HA   H N N 262 
MET HB2  H N N 263 
MET HB3  H N N 264 
MET HG2  H N N 265 
MET HG3  H N N 266 
MET HE1  H N N 267 
MET HE2  H N N 268 
MET HE3  H N N 269 
MET HXT  H N N 270 
NAG C1   C N R 271 
NAG C2   C N R 272 
NAG C3   C N R 273 
NAG C4   C N S 274 
NAG C5   C N R 275 
NAG C6   C N N 276 
NAG C7   C N N 277 
NAG C8   C N N 278 
NAG N2   N N N 279 
NAG O1   O N N 280 
NAG O3   O N N 281 
NAG O4   O N N 282 
NAG O5   O N N 283 
NAG O6   O N N 284 
NAG O7   O N N 285 
NAG H1   H N N 286 
NAG H2   H N N 287 
NAG H3   H N N 288 
NAG H4   H N N 289 
NAG H5   H N N 290 
NAG H61  H N N 291 
NAG H62  H N N 292 
NAG H81  H N N 293 
NAG H82  H N N 294 
NAG H83  H N N 295 
NAG HN2  H N N 296 
NAG HO1  H N N 297 
NAG HO3  H N N 298 
NAG HO4  H N N 299 
NAG HO6  H N N 300 
PHE N    N N N 301 
PHE CA   C N S 302 
PHE C    C N N 303 
PHE O    O N N 304 
PHE CB   C N N 305 
PHE CG   C Y N 306 
PHE CD1  C Y N 307 
PHE CD2  C Y N 308 
PHE CE1  C Y N 309 
PHE CE2  C Y N 310 
PHE CZ   C Y N 311 
PHE OXT  O N N 312 
PHE H    H N N 313 
PHE H2   H N N 314 
PHE HA   H N N 315 
PHE HB2  H N N 316 
PHE HB3  H N N 317 
PHE HD1  H N N 318 
PHE HD2  H N N 319 
PHE HE1  H N N 320 
PHE HE2  H N N 321 
PHE HZ   H N N 322 
PHE HXT  H N N 323 
PRO N    N N N 324 
PRO CA   C N S 325 
PRO C    C N N 326 
PRO O    O N N 327 
PRO CB   C N N 328 
PRO CG   C N N 329 
PRO CD   C N N 330 
PRO OXT  O N N 331 
PRO H    H N N 332 
PRO HA   H N N 333 
PRO HB2  H N N 334 
PRO HB3  H N N 335 
PRO HG2  H N N 336 
PRO HG3  H N N 337 
PRO HD2  H N N 338 
PRO HD3  H N N 339 
PRO HXT  H N N 340 
SER N    N N N 341 
SER CA   C N S 342 
SER C    C N N 343 
SER O    O N N 344 
SER CB   C N N 345 
SER OG   O N N 346 
SER OXT  O N N 347 
SER H    H N N 348 
SER H2   H N N 349 
SER HA   H N N 350 
SER HB2  H N N 351 
SER HB3  H N N 352 
SER HG   H N N 353 
SER HXT  H N N 354 
THR N    N N N 355 
THR CA   C N S 356 
THR C    C N N 357 
THR O    O N N 358 
THR CB   C N R 359 
THR OG1  O N N 360 
THR CG2  C N N 361 
THR OXT  O N N 362 
THR H    H N N 363 
THR H2   H N N 364 
THR HA   H N N 365 
THR HB   H N N 366 
THR HG1  H N N 367 
THR HG21 H N N 368 
THR HG22 H N N 369 
THR HG23 H N N 370 
THR HXT  H N N 371 
TRP N    N N N 372 
TRP CA   C N S 373 
TRP C    C N N 374 
TRP O    O N N 375 
TRP CB   C N N 376 
TRP CG   C Y N 377 
TRP CD1  C Y N 378 
TRP CD2  C Y N 379 
TRP NE1  N Y N 380 
TRP CE2  C Y N 381 
TRP CE3  C Y N 382 
TRP CZ2  C Y N 383 
TRP CZ3  C Y N 384 
TRP CH2  C Y N 385 
TRP OXT  O N N 386 
TRP H    H N N 387 
TRP H2   H N N 388 
TRP HA   H N N 389 
TRP HB2  H N N 390 
TRP HB3  H N N 391 
TRP HD1  H N N 392 
TRP HE1  H N N 393 
TRP HE3  H N N 394 
TRP HZ2  H N N 395 
TRP HZ3  H N N 396 
TRP HH2  H N N 397 
TRP HXT  H N N 398 
TYR N    N N N 399 
TYR CA   C N S 400 
TYR C    C N N 401 
TYR O    O N N 402 
TYR CB   C N N 403 
TYR CG   C Y N 404 
TYR CD1  C Y N 405 
TYR CD2  C Y N 406 
TYR CE1  C Y N 407 
TYR CE2  C Y N 408 
TYR CZ   C Y N 409 
TYR OH   O N N 410 
TYR OXT  O N N 411 
TYR H    H N N 412 
TYR H2   H N N 413 
TYR HA   H N N 414 
TYR HB2  H N N 415 
TYR HB3  H N N 416 
TYR HD1  H N N 417 
TYR HD2  H N N 418 
TYR HE1  H N N 419 
TYR HE2  H N N 420 
TYR HH   H N N 421 
TYR HXT  H N N 422 
VAL N    N N N 423 
VAL CA   C N S 424 
VAL C    C N N 425 
VAL O    O N N 426 
VAL CB   C N N 427 
VAL CG1  C N N 428 
VAL CG2  C N N 429 
VAL OXT  O N N 430 
VAL H    H N N 431 
VAL H2   H N N 432 
VAL HA   H N N 433 
VAL HB   H N N 434 
VAL HG11 H N N 435 
VAL HG12 H N N 436 
VAL HG13 H N N 437 
VAL HG21 H N N 438 
VAL HG22 H N N 439 
VAL HG23 H N N 440 
VAL HXT  H N N 441 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
BMA C1  C2   sing N N 70  
BMA C1  O1   sing N N 71  
BMA C1  O5   sing N N 72  
BMA C1  H1   sing N N 73  
BMA C2  C3   sing N N 74  
BMA C2  O2   sing N N 75  
BMA C2  H2   sing N N 76  
BMA C3  C4   sing N N 77  
BMA C3  O3   sing N N 78  
BMA C3  H3   sing N N 79  
BMA C4  C5   sing N N 80  
BMA C4  O4   sing N N 81  
BMA C4  H4   sing N N 82  
BMA C5  C6   sing N N 83  
BMA C5  O5   sing N N 84  
BMA C5  H5   sing N N 85  
BMA C6  O6   sing N N 86  
BMA C6  H61  sing N N 87  
BMA C6  H62  sing N N 88  
BMA O1  HO1  sing N N 89  
BMA O2  HO2  sing N N 90  
BMA O3  HO3  sing N N 91  
BMA O4  HO4  sing N N 92  
BMA O6  HO6  sing N N 93  
CYS N   CA   sing N N 94  
CYS N   H    sing N N 95  
CYS N   H2   sing N N 96  
CYS CA  C    sing N N 97  
CYS CA  CB   sing N N 98  
CYS CA  HA   sing N N 99  
CYS C   O    doub N N 100 
CYS C   OXT  sing N N 101 
CYS CB  SG   sing N N 102 
CYS CB  HB2  sing N N 103 
CYS CB  HB3  sing N N 104 
CYS SG  HG   sing N N 105 
CYS OXT HXT  sing N N 106 
GLN N   CA   sing N N 107 
GLN N   H    sing N N 108 
GLN N   H2   sing N N 109 
GLN CA  C    sing N N 110 
GLN CA  CB   sing N N 111 
GLN CA  HA   sing N N 112 
GLN C   O    doub N N 113 
GLN C   OXT  sing N N 114 
GLN CB  CG   sing N N 115 
GLN CB  HB2  sing N N 116 
GLN CB  HB3  sing N N 117 
GLN CG  CD   sing N N 118 
GLN CG  HG2  sing N N 119 
GLN CG  HG3  sing N N 120 
GLN CD  OE1  doub N N 121 
GLN CD  NE2  sing N N 122 
GLN NE2 HE21 sing N N 123 
GLN NE2 HE22 sing N N 124 
GLN OXT HXT  sing N N 125 
GLU N   CA   sing N N 126 
GLU N   H    sing N N 127 
GLU N   H2   sing N N 128 
GLU CA  C    sing N N 129 
GLU CA  CB   sing N N 130 
GLU CA  HA   sing N N 131 
GLU C   O    doub N N 132 
GLU C   OXT  sing N N 133 
GLU CB  CG   sing N N 134 
GLU CB  HB2  sing N N 135 
GLU CB  HB3  sing N N 136 
GLU CG  CD   sing N N 137 
GLU CG  HG2  sing N N 138 
GLU CG  HG3  sing N N 139 
GLU CD  OE1  doub N N 140 
GLU CD  OE2  sing N N 141 
GLU OE2 HE2  sing N N 142 
GLU OXT HXT  sing N N 143 
GLY N   CA   sing N N 144 
GLY N   H    sing N N 145 
GLY N   H2   sing N N 146 
GLY CA  C    sing N N 147 
GLY CA  HA2  sing N N 148 
GLY CA  HA3  sing N N 149 
GLY C   O    doub N N 150 
GLY C   OXT  sing N N 151 
GLY OXT HXT  sing N N 152 
HIS N   CA   sing N N 153 
HIS N   H    sing N N 154 
HIS N   H2   sing N N 155 
HIS CA  C    sing N N 156 
HIS CA  CB   sing N N 157 
HIS CA  HA   sing N N 158 
HIS C   O    doub N N 159 
HIS C   OXT  sing N N 160 
HIS CB  CG   sing N N 161 
HIS CB  HB2  sing N N 162 
HIS CB  HB3  sing N N 163 
HIS CG  ND1  sing Y N 164 
HIS CG  CD2  doub Y N 165 
HIS ND1 CE1  doub Y N 166 
HIS ND1 HD1  sing N N 167 
HIS CD2 NE2  sing Y N 168 
HIS CD2 HD2  sing N N 169 
HIS CE1 NE2  sing Y N 170 
HIS CE1 HE1  sing N N 171 
HIS NE2 HE2  sing N N 172 
HIS OXT HXT  sing N N 173 
ILE N   CA   sing N N 174 
ILE N   H    sing N N 175 
ILE N   H2   sing N N 176 
ILE CA  C    sing N N 177 
ILE CA  CB   sing N N 178 
ILE CA  HA   sing N N 179 
ILE C   O    doub N N 180 
ILE C   OXT  sing N N 181 
ILE CB  CG1  sing N N 182 
ILE CB  CG2  sing N N 183 
ILE CB  HB   sing N N 184 
ILE CG1 CD1  sing N N 185 
ILE CG1 HG12 sing N N 186 
ILE CG1 HG13 sing N N 187 
ILE CG2 HG21 sing N N 188 
ILE CG2 HG22 sing N N 189 
ILE CG2 HG23 sing N N 190 
ILE CD1 HD11 sing N N 191 
ILE CD1 HD12 sing N N 192 
ILE CD1 HD13 sing N N 193 
ILE OXT HXT  sing N N 194 
LEU N   CA   sing N N 195 
LEU N   H    sing N N 196 
LEU N   H2   sing N N 197 
LEU CA  C    sing N N 198 
LEU CA  CB   sing N N 199 
LEU CA  HA   sing N N 200 
LEU C   O    doub N N 201 
LEU C   OXT  sing N N 202 
LEU CB  CG   sing N N 203 
LEU CB  HB2  sing N N 204 
LEU CB  HB3  sing N N 205 
LEU CG  CD1  sing N N 206 
LEU CG  CD2  sing N N 207 
LEU CG  HG   sing N N 208 
LEU CD1 HD11 sing N N 209 
LEU CD1 HD12 sing N N 210 
LEU CD1 HD13 sing N N 211 
LEU CD2 HD21 sing N N 212 
LEU CD2 HD22 sing N N 213 
LEU CD2 HD23 sing N N 214 
LEU OXT HXT  sing N N 215 
LYS N   CA   sing N N 216 
LYS N   H    sing N N 217 
LYS N   H2   sing N N 218 
LYS CA  C    sing N N 219 
LYS CA  CB   sing N N 220 
LYS CA  HA   sing N N 221 
LYS C   O    doub N N 222 
LYS C   OXT  sing N N 223 
LYS CB  CG   sing N N 224 
LYS CB  HB2  sing N N 225 
LYS CB  HB3  sing N N 226 
LYS CG  CD   sing N N 227 
LYS CG  HG2  sing N N 228 
LYS CG  HG3  sing N N 229 
LYS CD  CE   sing N N 230 
LYS CD  HD2  sing N N 231 
LYS CD  HD3  sing N N 232 
LYS CE  NZ   sing N N 233 
LYS CE  HE2  sing N N 234 
LYS CE  HE3  sing N N 235 
LYS NZ  HZ1  sing N N 236 
LYS NZ  HZ2  sing N N 237 
LYS NZ  HZ3  sing N N 238 
LYS OXT HXT  sing N N 239 
MET N   CA   sing N N 240 
MET N   H    sing N N 241 
MET N   H2   sing N N 242 
MET CA  C    sing N N 243 
MET CA  CB   sing N N 244 
MET CA  HA   sing N N 245 
MET C   O    doub N N 246 
MET C   OXT  sing N N 247 
MET CB  CG   sing N N 248 
MET CB  HB2  sing N N 249 
MET CB  HB3  sing N N 250 
MET CG  SD   sing N N 251 
MET CG  HG2  sing N N 252 
MET CG  HG3  sing N N 253 
MET SD  CE   sing N N 254 
MET CE  HE1  sing N N 255 
MET CE  HE2  sing N N 256 
MET CE  HE3  sing N N 257 
MET OXT HXT  sing N N 258 
NAG C1  C2   sing N N 259 
NAG C1  O1   sing N N 260 
NAG C1  O5   sing N N 261 
NAG C1  H1   sing N N 262 
NAG C2  C3   sing N N 263 
NAG C2  N2   sing N N 264 
NAG C2  H2   sing N N 265 
NAG C3  C4   sing N N 266 
NAG C3  O3   sing N N 267 
NAG C3  H3   sing N N 268 
NAG C4  C5   sing N N 269 
NAG C4  O4   sing N N 270 
NAG C4  H4   sing N N 271 
NAG C5  C6   sing N N 272 
NAG C5  O5   sing N N 273 
NAG C5  H5   sing N N 274 
NAG C6  O6   sing N N 275 
NAG C6  H61  sing N N 276 
NAG C6  H62  sing N N 277 
NAG C7  C8   sing N N 278 
NAG C7  N2   sing N N 279 
NAG C7  O7   doub N N 280 
NAG C8  H81  sing N N 281 
NAG C8  H82  sing N N 282 
NAG C8  H83  sing N N 283 
NAG N2  HN2  sing N N 284 
NAG O1  HO1  sing N N 285 
NAG O3  HO3  sing N N 286 
NAG O4  HO4  sing N N 287 
NAG O6  HO6  sing N N 288 
PHE N   CA   sing N N 289 
PHE N   H    sing N N 290 
PHE N   H2   sing N N 291 
PHE CA  C    sing N N 292 
PHE CA  CB   sing N N 293 
PHE CA  HA   sing N N 294 
PHE C   O    doub N N 295 
PHE C   OXT  sing N N 296 
PHE CB  CG   sing N N 297 
PHE CB  HB2  sing N N 298 
PHE CB  HB3  sing N N 299 
PHE CG  CD1  doub Y N 300 
PHE CG  CD2  sing Y N 301 
PHE CD1 CE1  sing Y N 302 
PHE CD1 HD1  sing N N 303 
PHE CD2 CE2  doub Y N 304 
PHE CD2 HD2  sing N N 305 
PHE CE1 CZ   doub Y N 306 
PHE CE1 HE1  sing N N 307 
PHE CE2 CZ   sing Y N 308 
PHE CE2 HE2  sing N N 309 
PHE CZ  HZ   sing N N 310 
PHE OXT HXT  sing N N 311 
PRO N   CA   sing N N 312 
PRO N   CD   sing N N 313 
PRO N   H    sing N N 314 
PRO CA  C    sing N N 315 
PRO CA  CB   sing N N 316 
PRO CA  HA   sing N N 317 
PRO C   O    doub N N 318 
PRO C   OXT  sing N N 319 
PRO CB  CG   sing N N 320 
PRO CB  HB2  sing N N 321 
PRO CB  HB3  sing N N 322 
PRO CG  CD   sing N N 323 
PRO CG  HG2  sing N N 324 
PRO CG  HG3  sing N N 325 
PRO CD  HD2  sing N N 326 
PRO CD  HD3  sing N N 327 
PRO OXT HXT  sing N N 328 
SER N   CA   sing N N 329 
SER N   H    sing N N 330 
SER N   H2   sing N N 331 
SER CA  C    sing N N 332 
SER CA  CB   sing N N 333 
SER CA  HA   sing N N 334 
SER C   O    doub N N 335 
SER C   OXT  sing N N 336 
SER CB  OG   sing N N 337 
SER CB  HB2  sing N N 338 
SER CB  HB3  sing N N 339 
SER OG  HG   sing N N 340 
SER OXT HXT  sing N N 341 
THR N   CA   sing N N 342 
THR N   H    sing N N 343 
THR N   H2   sing N N 344 
THR CA  C    sing N N 345 
THR CA  CB   sing N N 346 
THR CA  HA   sing N N 347 
THR C   O    doub N N 348 
THR C   OXT  sing N N 349 
THR CB  OG1  sing N N 350 
THR CB  CG2  sing N N 351 
THR CB  HB   sing N N 352 
THR OG1 HG1  sing N N 353 
THR CG2 HG21 sing N N 354 
THR CG2 HG22 sing N N 355 
THR CG2 HG23 sing N N 356 
THR OXT HXT  sing N N 357 
TRP N   CA   sing N N 358 
TRP N   H    sing N N 359 
TRP N   H2   sing N N 360 
TRP CA  C    sing N N 361 
TRP CA  CB   sing N N 362 
TRP CA  HA   sing N N 363 
TRP C   O    doub N N 364 
TRP C   OXT  sing N N 365 
TRP CB  CG   sing N N 366 
TRP CB  HB2  sing N N 367 
TRP CB  HB3  sing N N 368 
TRP CG  CD1  doub Y N 369 
TRP CG  CD2  sing Y N 370 
TRP CD1 NE1  sing Y N 371 
TRP CD1 HD1  sing N N 372 
TRP CD2 CE2  doub Y N 373 
TRP CD2 CE3  sing Y N 374 
TRP NE1 CE2  sing Y N 375 
TRP NE1 HE1  sing N N 376 
TRP CE2 CZ2  sing Y N 377 
TRP CE3 CZ3  doub Y N 378 
TRP CE3 HE3  sing N N 379 
TRP CZ2 CH2  doub Y N 380 
TRP CZ2 HZ2  sing N N 381 
TRP CZ3 CH2  sing Y N 382 
TRP CZ3 HZ3  sing N N 383 
TRP CH2 HH2  sing N N 384 
TRP OXT HXT  sing N N 385 
TYR N   CA   sing N N 386 
TYR N   H    sing N N 387 
TYR N   H2   sing N N 388 
TYR CA  C    sing N N 389 
TYR CA  CB   sing N N 390 
TYR CA  HA   sing N N 391 
TYR C   O    doub N N 392 
TYR C   OXT  sing N N 393 
TYR CB  CG   sing N N 394 
TYR CB  HB2  sing N N 395 
TYR CB  HB3  sing N N 396 
TYR CG  CD1  doub Y N 397 
TYR CG  CD2  sing Y N 398 
TYR CD1 CE1  sing Y N 399 
TYR CD1 HD1  sing N N 400 
TYR CD2 CE2  doub Y N 401 
TYR CD2 HD2  sing N N 402 
TYR CE1 CZ   doub Y N 403 
TYR CE1 HE1  sing N N 404 
TYR CE2 CZ   sing Y N 405 
TYR CE2 HE2  sing N N 406 
TYR CZ  OH   sing N N 407 
TYR OH  HH   sing N N 408 
TYR OXT HXT  sing N N 409 
VAL N   CA   sing N N 410 
VAL N   H    sing N N 411 
VAL N   H2   sing N N 412 
VAL CA  C    sing N N 413 
VAL CA  CB   sing N N 414 
VAL CA  HA   sing N N 415 
VAL C   O    doub N N 416 
VAL C   OXT  sing N N 417 
VAL CB  CG1  sing N N 418 
VAL CB  CG2  sing N N 419 
VAL CB  HB   sing N N 420 
VAL CG1 HG11 sing N N 421 
VAL CG1 HG12 sing N N 422 
VAL CG1 HG13 sing N N 423 
VAL CG2 HG21 sing N N 424 
VAL CG2 HG22 sing N N 425 
VAL CG2 HG23 sing N N 426 
VAL OXT HXT  sing N N 427 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-04-19 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           8Z7B 
_em_admin.last_update        2025-02-05 
_em_admin.map_release_date   2025-02-05 
_em_admin.title              
;Cryo-EM structure of SARS-CoV-2 S trimer in the early fusion intermediate conformation (E-FIC) (focused refinement of NTD-SD1-RBD-ACE2)
;
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
loop_
_em_entity_assembly_naturalsource.cell 
_em_entity_assembly_naturalsource.cellular_location 
_em_entity_assembly_naturalsource.entity_assembly_id 
_em_entity_assembly_naturalsource.id 
_em_entity_assembly_naturalsource.ncbi_tax_id 
_em_entity_assembly_naturalsource.organism 
_em_entity_assembly_naturalsource.organelle 
_em_entity_assembly_naturalsource.organ 
_em_entity_assembly_naturalsource.strain 
_em_entity_assembly_naturalsource.tissue 
_em_entity_assembly_naturalsource.details 
? ? 2 2 2697049 'Severe acute respiratory syndrome coronavirus 2' ? ? ? ? ? 
? ? 3 3 9606    'Homo sapiens'                                    ? ? ? ? ? 
# 
loop_
_em_entity_assembly_recombinant.cell 
_em_entity_assembly_recombinant.entity_assembly_id 
_em_entity_assembly_recombinant.id 
_em_entity_assembly_recombinant.ncbi_tax_id 
_em_entity_assembly_recombinant.organism 
_em_entity_assembly_recombinant.plasmid 
_em_entity_assembly_recombinant.strain 
? 2 2 9606 'Homo sapiens' ? ? 
? 3 3 9606 'Homo sapiens' ? ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         50 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'FEI FALCON IV (4k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? ? ? 
'IMAGE ACQUISITION'        ? 2  ? ? 1 ? ? 
MASKING                    ? 3  ? ? ? ? ? 
'CTF CORRECTION'           ? 4  1 ? ? ? ? 
'LAYERLINE INDEXING'       ? 5  ? ? ? ? ? 
'DIFFRACTION INDEXING'     ? 6  ? ? ? ? ? 
'MODEL FITTING'            ? 7  ? ? ? ? ? 
'MODEL REFINEMENT'         ? 8  ? ? ? ? ? 
OTHER                      ? 9  ? ? ? ? ? 
'INITIAL EULER ASSIGNMENT' ? 10 1 ? ? ? ? 
'FINAL EULER ASSIGNMENT'   ? 11 1 ? ? ? ? 
CLASSIFICATION             ? 12 1 ? ? ? ? 
RECONSTRUCTION             ? 13 1 ? ? ? ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'Ministry of Science and Technology (MoST, China)'                                  China 2021YFC2302500 1 
'National Natural Science Foundation of China (NSFC)'                               China '82394463; 92169112; 82341036' 2 
'National Key R&D Program of China'                                                 China 
'2022YFC2604100; 2021YFC2300703; 2023YFC2307800' 3 
'Non-profit Central Research Institute Fund of Chinese Academy of Medical Sciences' China 2023-PT310-02 4 
'Major Project of Guangzhou National Laboratory'                                    China 'GZNL2023A01008; GZNL2024A01008' 5 
'R&D Program of Guangzhou Laboratory'                                               China SRPG22-003 6 
'Shanghai Municipal Science and Technology Major Project'                           China ZD2021CY001 7 
# 
loop_
_pdbx_entity_branch_list.entity_id 
_pdbx_entity_branch_list.comp_id 
_pdbx_entity_branch_list.num 
_pdbx_entity_branch_list.hetero 
3 NAG 1 n 
3 NAG 2 n 
4 NAG 1 n 
4 NAG 2 n 
4 BMA 3 n 
# 
_atom_sites.entry_id                    8Z7B 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . SER A 1 19  ? 221.851 190.806 153.286 1.00 60.82  ? 19   SER D N   1 
ATOM   2    C CA  . SER A 1 19  ? 222.201 189.912 152.188 1.00 60.82  ? 19   SER D CA  1 
ATOM   3    C C   . SER A 1 19  ? 221.750 190.486 150.850 1.00 60.82  ? 19   SER D C   1 
ATOM   4    O O   . SER A 1 19  ? 222.383 190.256 149.820 1.00 60.82  ? 19   SER D O   1 
ATOM   5    C CB  . SER A 1 19  ? 221.583 188.529 152.404 1.00 60.82  ? 19   SER D CB  1 
ATOM   6    O OG  . SER A 1 19  ? 221.927 187.646 151.351 1.00 60.82  ? 19   SER D OG  1 
ATOM   7    N N   . THR A 1 20  ? 220.651 191.235 150.871 1.00 60.61  ? 20   THR D N   1 
ATOM   8    C CA  . THR A 1 20  ? 220.127 191.843 149.660 1.00 60.61  ? 20   THR D CA  1 
ATOM   9    C C   . THR A 1 20  ? 220.977 193.046 149.255 1.00 60.61  ? 20   THR D C   1 
ATOM   10   O O   . THR A 1 20  ? 221.829 193.527 150.007 1.00 60.61  ? 20   THR D O   1 
ATOM   11   C CB  . THR A 1 20  ? 218.671 192.263 149.854 1.00 60.61  ? 20   THR D CB  1 
ATOM   12   O OG1 . THR A 1 20  ? 218.582 193.209 150.927 1.00 60.61  ? 20   THR D OG1 1 
ATOM   13   C CG2 . THR A 1 20  ? 217.807 191.054 150.178 1.00 60.61  ? 20   THR D CG2 1 
ATOM   14   N N   . ILE A 1 21  ? 220.729 193.537 148.039 1.00 59.55  ? 21   ILE D N   1 
ATOM   15   C CA  . ILE A 1 21  ? 221.490 194.673 147.531 1.00 59.55  ? 21   ILE D CA  1 
ATOM   16   C C   . ILE A 1 21  ? 221.085 195.957 148.244 1.00 59.55  ? 21   ILE D C   1 
ATOM   17   O O   . ILE A 1 21  ? 221.911 196.860 148.429 1.00 59.55  ? 21   ILE D O   1 
ATOM   18   C CB  . ILE A 1 21  ? 221.311 194.788 146.005 1.00 59.55  ? 21   ILE D CB  1 
ATOM   19   C CG1 . ILE A 1 21  ? 221.677 193.466 145.329 1.00 59.55  ? 21   ILE D CG1 1 
ATOM   20   C CG2 . ILE A 1 21  ? 222.163 195.915 145.443 1.00 59.55  ? 21   ILE D CG2 1 
ATOM   21   C CD1 . ILE A 1 21  ? 223.113 193.046 145.549 1.00 59.55  ? 21   ILE D CD1 1 
ATOM   22   N N   . GLU A 1 22  ? 219.823 196.059 148.668 1.00 60.18  ? 22   GLU D N   1 
ATOM   23   C CA  . GLU A 1 22  ? 219.365 197.271 149.339 1.00 60.18  ? 22   GLU D CA  1 
ATOM   24   C C   . GLU A 1 22  ? 220.041 197.447 150.694 1.00 60.18  ? 22   GLU D C   1 
ATOM   25   O O   . GLU A 1 22  ? 220.393 198.569 151.076 1.00 60.18  ? 22   GLU D O   1 
ATOM   26   C CB  . GLU A 1 22  ? 217.845 197.242 149.490 1.00 60.18  ? 22   GLU D CB  1 
ATOM   27   C CG  . GLU A 1 22  ? 217.252 198.517 150.065 1.00 60.18  ? 22   GLU D CG  1 
ATOM   28   C CD  . GLU A 1 22  ? 215.737 198.516 150.041 1.00 60.18  ? 22   GLU D CD  1 
ATOM   29   O OE1 . GLU A 1 22  ? 215.151 197.590 149.443 1.00 60.18  ? 22   GLU D OE1 1 
ATOM   30   O OE2 . GLU A 1 22  ? 215.131 199.441 150.621 1.00 60.18  ? 22   GLU D OE2 1 
ATOM   31   N N   . GLU A 1 23  ? 220.243 196.352 151.430 1.00 61.67  ? 23   GLU D N   1 
ATOM   32   C CA  . GLU A 1 23  ? 220.917 196.449 152.722 1.00 61.67  ? 23   GLU D CA  1 
ATOM   33   C C   . GLU A 1 23  ? 222.381 196.840 152.555 1.00 61.67  ? 23   GLU D C   1 
ATOM   34   O O   . GLU A 1 23  ? 222.907 197.650 153.330 1.00 61.67  ? 23   GLU D O   1 
ATOM   35   C CB  . GLU A 1 23  ? 220.794 195.126 153.477 1.00 61.67  ? 23   GLU D CB  1 
ATOM   36   C CG  . GLU A 1 23  ? 219.360 194.719 153.776 1.00 61.67  ? 23   GLU D CG  1 
ATOM   37   C CD  . GLU A 1 23  ? 219.271 193.398 154.513 1.00 61.67  ? 23   GLU D CD  1 
ATOM   38   O OE1 . GLU A 1 23  ? 220.331 192.798 154.792 1.00 61.67  ? 23   GLU D OE1 1 
ATOM   39   O OE2 . GLU A 1 23  ? 218.142 192.959 154.815 1.00 61.67  ? 23   GLU D OE2 1 
ATOM   40   N N   . GLN A 1 24  ? 223.056 196.275 151.550 1.00 58.97  ? 24   GLN D N   1 
ATOM   41   C CA  . GLN A 1 24  ? 224.433 196.671 151.272 1.00 58.97  ? 24   GLN D CA  1 
ATOM   42   C C   . GLN A 1 24  ? 224.508 198.138 150.871 1.00 58.97  ? 24   GLN D C   1 
ATOM   43   O O   . GLN A 1 24  ? 225.435 198.854 151.270 1.00 58.97  ? 24   GLN D O   1 
ATOM   44   C CB  . GLN A 1 24  ? 225.023 195.785 150.175 1.00 58.97  ? 24   GLN D CB  1 
ATOM   45   C CG  . GLN A 1 24  ? 224.983 194.299 150.483 1.00 58.97  ? 24   GLN D CG  1 
ATOM   46   C CD  . GLN A 1 24  ? 225.537 193.456 149.352 1.00 58.97  ? 24   GLN D CD  1 
ATOM   47   O OE1 . GLN A 1 24  ? 226.103 193.978 148.392 1.00 58.97  ? 24   GLN D OE1 1 
ATOM   48   N NE2 . GLN A 1 24  ? 225.375 192.142 149.459 1.00 58.97  ? 24   GLN D NE2 1 
ATOM   49   N N   . ALA A 1 25  ? 223.533 198.604 150.086 1.00 56.72  ? 25   ALA D N   1 
ATOM   50   C CA  . ALA A 1 25  ? 223.499 200.012 149.706 1.00 56.72  ? 25   ALA D CA  1 
ATOM   51   C C   . ALA A 1 25  ? 223.287 200.904 150.921 1.00 56.72  ? 25   ALA D C   1 
ATOM   52   O O   . ALA A 1 25  ? 223.907 201.966 151.033 1.00 56.72  ? 25   ALA D O   1 
ATOM   53   C CB  . ALA A 1 25  ? 222.404 200.249 148.665 1.00 56.72  ? 25   ALA D CB  1 
ATOM   54   N N   . LYS A 1 26  ? 222.418 200.488 151.845 1.00 56.18  ? 26   LYS D N   1 
ATOM   55   C CA  . LYS A 1 26  ? 222.201 201.269 153.060 1.00 56.18  ? 26   LYS D CA  1 
ATOM   56   C C   . LYS A 1 26  ? 223.457 201.314 153.922 1.00 56.18  ? 26   LYS D C   1 
ATOM   57   O O   . LYS A 1 26  ? 223.785 202.359 154.497 1.00 56.18  ? 26   LYS D O   1 
ATOM   58   C CB  . LYS A 1 26  ? 221.027 200.697 153.854 1.00 56.18  ? 26   LYS D CB  1 
ATOM   59   C CG  . LYS A 1 26  ? 219.673 200.886 153.192 1.00 56.18  ? 26   LYS D CG  1 
ATOM   60   C CD  . LYS A 1 26  ? 218.560 200.298 154.044 1.00 56.18  ? 26   LYS D CD  1 
ATOM   61   C CE  . LYS A 1 26  ? 217.208 200.452 153.370 1.00 56.18  ? 26   LYS D CE  1 
ATOM   62   N NZ  . LYS A 1 26  ? 216.112 199.865 154.189 1.00 56.18  ? 26   LYS D NZ  1 
ATOM   63   N N   . THR A 1 27  ? 224.176 200.193 154.022 1.00 55.25  ? 27   THR D N   1 
ATOM   64   C CA  . THR A 1 27  ? 225.417 200.179 154.792 1.00 55.25  ? 27   THR D CA  1 
ATOM   65   C C   . THR A 1 27  ? 226.468 201.086 154.160 1.00 55.25  ? 27   THR D C   1 
ATOM   66   O O   . THR A 1 27  ? 227.159 201.842 154.861 1.00 55.25  ? 27   THR D O   1 
ATOM   67   C CB  . THR A 1 27  ? 225.941 198.747 154.910 1.00 55.25  ? 27   THR D CB  1 
ATOM   68   O OG1 . THR A 1 27  ? 224.957 197.929 155.555 1.00 55.25  ? 27   THR D OG1 1 
ATOM   69   C CG2 . THR A 1 27  ? 227.227 198.710 155.718 1.00 55.25  ? 27   THR D CG2 1 
ATOM   70   N N   . PHE A 1 28  ? 226.600 201.026 152.833 1.00 54.92  ? 28   PHE D N   1 
ATOM   71   C CA  . PHE A 1 28  ? 227.536 201.905 152.139 1.00 54.92  ? 28   PHE D CA  1 
ATOM   72   C C   . PHE A 1 28  ? 227.150 203.368 152.316 1.00 54.92  ? 28   PHE D C   1 
ATOM   73   O O   . PHE A 1 28  ? 228.019 204.231 152.490 1.00 54.92  ? 28   PHE D O   1 
ATOM   74   C CB  . PHE A 1 28  ? 227.591 201.533 150.657 1.00 54.92  ? 28   PHE D CB  1 
ATOM   75   C CG  . PHE A 1 28  ? 228.485 202.419 149.841 1.00 54.92  ? 28   PHE D CG  1 
ATOM   76   C CD1 . PHE A 1 28  ? 229.857 202.230 149.841 1.00 54.92  ? 28   PHE D CD1 1 
ATOM   77   C CD2 . PHE A 1 28  ? 227.954 203.434 149.065 1.00 54.92  ? 28   PHE D CD2 1 
ATOM   78   C CE1 . PHE A 1 28  ? 230.680 203.042 149.089 1.00 54.92  ? 28   PHE D CE1 1 
ATOM   79   C CE2 . PHE A 1 28  ? 228.772 204.248 148.312 1.00 54.92  ? 28   PHE D CE2 1 
ATOM   80   C CZ  . PHE A 1 28  ? 230.136 204.052 148.322 1.00 54.92  ? 28   PHE D CZ  1 
ATOM   81   N N   . LEU A 1 29  ? 225.849 203.663 152.289 1.00 54.23  ? 29   LEU D N   1 
ATOM   82   C CA  . LEU A 1 29  ? 225.390 205.033 152.487 1.00 54.23  ? 29   LEU D CA  1 
ATOM   83   C C   . LEU A 1 29  ? 225.674 205.511 153.904 1.00 54.23  ? 29   LEU D C   1 
ATOM   84   O O   . LEU A 1 29  ? 226.010 206.680 154.110 1.00 54.23  ? 29   LEU D O   1 
ATOM   85   C CB  . LEU A 1 29  ? 223.898 205.137 152.174 1.00 54.23  ? 29   LEU D CB  1 
ATOM   86   C CG  . LEU A 1 29  ? 223.511 205.652 150.786 1.00 54.23  ? 29   LEU D CG  1 
ATOM   87   C CD1 . LEU A 1 29  ? 224.284 204.932 149.695 1.00 54.23  ? 29   LEU D CD1 1 
ATOM   88   C CD2 . LEU A 1 29  ? 222.015 205.497 150.572 1.00 54.23  ? 29   LEU D CD2 1 
ATOM   89   N N   . ASP A 1 30  ? 225.544 204.626 154.894 1.00 56.15  ? 30   ASP D N   1 
ATOM   90   C CA  . ASP A 1 30  ? 225.886 205.001 156.262 1.00 56.15  ? 30   ASP D CA  1 
ATOM   91   C C   . ASP A 1 30  ? 227.375 205.299 156.395 1.00 56.15  ? 30   ASP D C   1 
ATOM   92   O O   . ASP A 1 30  ? 227.764 206.295 157.019 1.00 56.15  ? 30   ASP D O   1 
ATOM   93   C CB  . ASP A 1 30  ? 225.469 203.897 157.233 1.00 56.15  ? 30   ASP D CB  1 
ATOM   94   C CG  . ASP A 1 30  ? 223.965 203.715 157.298 1.00 56.15  ? 30   ASP D CG  1 
ATOM   95   O OD1 . ASP A 1 30  ? 223.248 204.420 156.558 1.00 56.15  ? 30   ASP D OD1 1 
ATOM   96   O OD2 . ASP A 1 30  ? 223.501 202.870 158.091 1.00 56.15  ? 30   ASP D OD2 1 
ATOM   97   N N   . LYS A 1 31  ? 228.223 204.448 155.810 1.00 53.43  ? 31   LYS D N   1 
ATOM   98   C CA  . LYS A 1 31  ? 229.662 204.702 155.846 1.00 53.43  ? 31   LYS D CA  1 
ATOM   99   C C   . LYS A 1 31  ? 230.004 206.022 155.161 1.00 53.43  ? 31   LYS D C   1 
ATOM   100  O O   . LYS A 1 31  ? 230.842 206.794 155.653 1.00 53.43  ? 31   LYS D O   1 
ATOM   101  C CB  . LYS A 1 31  ? 230.412 203.541 155.192 1.00 53.43  ? 31   LYS D CB  1 
ATOM   102  C CG  . LYS A 1 31  ? 231.672 203.104 155.926 1.00 53.43  ? 31   LYS D CG  1 
ATOM   103  C CD  . LYS A 1 31  ? 232.765 204.156 155.856 1.00 53.43  ? 31   LYS D CD  1 
ATOM   104  C CE  . LYS A 1 31  ? 234.021 203.692 156.572 1.00 53.43  ? 31   LYS D CE  1 
ATOM   105  N NZ  . LYS A 1 31  ? 234.565 202.441 155.978 1.00 53.43  ? 31   LYS D NZ  1 
ATOM   106  N N   . PHE A 1 32  ? 229.358 206.301 154.026 1.00 54.03  ? 32   PHE D N   1 
ATOM   107  C CA  . PHE A 1 32  ? 229.599 207.554 153.320 1.00 54.03  ? 32   PHE D CA  1 
ATOM   108  C C   . PHE A 1 32  ? 229.137 208.751 154.142 1.00 54.03  ? 32   PHE D C   1 
ATOM   109  O O   . PHE A 1 32  ? 229.844 209.759 154.227 1.00 54.03  ? 32   PHE D O   1 
ATOM   110  C CB  . PHE A 1 32  ? 228.899 207.533 151.961 1.00 54.03  ? 32   PHE D CB  1 
ATOM   111  C CG  . PHE A 1 32  ? 229.082 208.792 151.165 1.00 54.03  ? 32   PHE D CG  1 
ATOM   112  C CD1 . PHE A 1 32  ? 230.227 208.991 150.413 1.00 54.03  ? 32   PHE D CD1 1 
ATOM   113  C CD2 . PHE A 1 32  ? 228.108 209.776 151.163 1.00 54.03  ? 32   PHE D CD2 1 
ATOM   114  C CE1 . PHE A 1 32  ? 230.399 210.148 149.679 1.00 54.03  ? 32   PHE D CE1 1 
ATOM   115  C CE2 . PHE A 1 32  ? 228.275 210.935 150.432 1.00 54.03  ? 32   PHE D CE2 1 
ATOM   116  C CZ  . PHE A 1 32  ? 229.422 211.121 149.688 1.00 54.03  ? 32   PHE D CZ  1 
ATOM   117  N N   . ASN A 1 33  ? 227.951 208.667 154.748 1.00 54.41  ? 33   ASN D N   1 
ATOM   118  C CA  . ASN A 1 33  ? 227.464 209.767 155.570 1.00 54.41  ? 33   ASN D CA  1 
ATOM   119  C C   . ASN A 1 33  ? 228.340 209.979 156.796 1.00 54.41  ? 33   ASN D C   1 
ATOM   120  O O   . ASN A 1 33  ? 228.390 211.089 157.334 1.00 54.41  ? 33   ASN D O   1 
ATOM   121  C CB  . ASN A 1 33  ? 226.015 209.516 155.989 1.00 54.41  ? 33   ASN D CB  1 
ATOM   122  C CG  . ASN A 1 33  ? 225.040 209.676 154.840 1.00 54.41  ? 33   ASN D CG  1 
ATOM   123  O OD1 . ASN A 1 33  ? 224.625 210.787 154.513 1.00 54.41  ? 33   ASN D OD1 1 
ATOM   124  N ND2 . ASN A 1 33  ? 224.663 208.562 154.224 1.00 54.41  ? 33   ASN D ND2 1 
ATOM   125  N N   . HIS A 1 34  ? 229.031 208.935 157.254 1.00 54.01  ? 34   HIS D N   1 
ATOM   126  C CA  . HIS A 1 34  ? 229.962 209.121 158.361 1.00 54.01  ? 34   HIS D CA  1 
ATOM   127  C C   . HIS A 1 34  ? 231.240 209.819 157.907 1.00 54.01  ? 34   HIS D C   1 
ATOM   128  O O   . HIS A 1 34  ? 231.686 210.784 158.538 1.00 54.01  ? 34   HIS D O   1 
ATOM   129  C CB  . HIS A 1 34  ? 230.298 207.781 159.013 1.00 54.01  ? 34   HIS D CB  1 
ATOM   130  C CG  . HIS A 1 34  ? 231.341 207.883 160.081 1.00 54.01  ? 34   HIS D CG  1 
ATOM   131  N ND1 . HIS A 1 34  ? 231.083 208.420 161.324 1.00 54.01  ? 34   HIS D ND1 1 
ATOM   132  C CD2 . HIS A 1 34  ? 232.650 207.538 160.085 1.00 54.01  ? 34   HIS D CD2 1 
ATOM   133  C CE1 . HIS A 1 34  ? 232.185 208.390 162.051 1.00 54.01  ? 34   HIS D CE1 1 
ATOM   134  N NE2 . HIS A 1 34  ? 233.151 207.861 161.323 1.00 54.01  ? 34   HIS D NE2 1 
ATOM   135  N N   . GLU A 1 35  ? 231.845 209.347 156.814 1.00 55.79  ? 35   GLU D N   1 
ATOM   136  C CA  . GLU A 1 35  ? 233.151 209.871 156.414 1.00 55.79  ? 35   GLU D CA  1 
ATOM   137  C C   . GLU A 1 35  ? 233.041 211.238 155.739 1.00 55.79  ? 35   GLU D C   1 
ATOM   138  O O   . GLU A 1 35  ? 233.748 212.189 156.113 1.00 55.79  ? 35   GLU D O   1 
ATOM   139  C CB  . GLU A 1 35  ? 233.852 208.875 155.488 1.00 55.79  ? 35   GLU D CB  1 
ATOM   140  C CG  . GLU A 1 35  ? 234.223 207.558 156.150 1.00 55.79  ? 35   GLU D CG  1 
ATOM   141  C CD  . GLU A 1 35  ? 235.376 207.697 157.125 1.00 55.79  ? 35   GLU D CD  1 
ATOM   142  O OE1 . GLU A 1 35  ? 236.108 208.705 157.046 1.00 55.79  ? 35   GLU D OE1 1 
ATOM   143  O OE2 . GLU A 1 35  ? 235.551 206.795 157.972 1.00 55.79  ? 35   GLU D OE2 1 
ATOM   144  N N   . ALA A 1 36  ? 232.174 211.343 154.727 1.00 55.66  ? 36   ALA D N   1 
ATOM   145  C CA  . ALA A 1 36  ? 232.059 212.572 153.954 1.00 55.66  ? 36   ALA D CA  1 
ATOM   146  C C   . ALA A 1 36  ? 231.635 213.750 154.816 1.00 55.66  ? 36   ALA D C   1 
ATOM   147  O O   . ALA A 1 36  ? 232.010 214.886 154.523 1.00 55.66  ? 36   ALA D O   1 
ATOM   148  C CB  . ALA A 1 36  ? 231.068 212.376 152.806 1.00 55.66  ? 36   ALA D CB  1 
ATOM   149  N N   . GLU A 1 37  ? 230.862 213.508 155.877 1.00 55.98  ? 37   GLU D N   1 
ATOM   150  C CA  . GLU A 1 37  ? 230.477 214.603 156.763 1.00 55.98  ? 37   GLU D CA  1 
ATOM   151  C C   . GLU A 1 37  ? 231.704 215.280 157.360 1.00 55.98  ? 37   GLU D C   1 
ATOM   152  O O   . GLU A 1 37  ? 231.877 216.498 157.236 1.00 55.98  ? 37   GLU D O   1 
ATOM   153  C CB  . GLU A 1 37  ? 229.552 214.093 157.868 1.00 55.98  ? 37   GLU D CB  1 
ATOM   154  C CG  . GLU A 1 37  ? 228.075 214.219 157.540 1.00 55.98  ? 37   GLU D CG  1 
ATOM   155  C CD  . GLU A 1 37  ? 227.185 213.783 158.686 1.00 55.98  ? 37   GLU D CD  1 
ATOM   156  O OE1 . GLU A 1 37  ? 227.723 213.417 159.752 1.00 55.98  ? 37   GLU D OE1 1 
ATOM   157  O OE2 . GLU A 1 37  ? 225.948 213.807 158.522 1.00 55.98  ? 37   GLU D OE2 1 
ATOM   158  N N   . ASP A 1 38  ? 232.577 214.499 157.999 1.00 55.19  ? 38   ASP D N   1 
ATOM   159  C CA  . ASP A 1 38  ? 233.774 215.072 158.607 1.00 55.19  ? 38   ASP D CA  1 
ATOM   160  C C   . ASP A 1 38  ? 234.704 215.660 157.552 1.00 55.19  ? 38   ASP D C   1 
ATOM   161  O O   . ASP A 1 38  ? 235.301 216.726 157.764 1.00 55.19  ? 38   ASP D O   1 
ATOM   162  C CB  . ASP A 1 38  ? 234.501 214.011 159.432 1.00 55.19  ? 38   ASP D CB  1 
ATOM   163  C CG  . ASP A 1 38  ? 235.714 214.563 160.153 1.00 55.19  ? 38   ASP D CG  1 
ATOM   164  O OD1 . ASP A 1 38  ? 235.533 215.328 161.123 1.00 55.19  ? 38   ASP D OD1 1 
ATOM   165  O OD2 . ASP A 1 38  ? 236.848 214.232 159.750 1.00 55.19  ? 38   ASP D OD2 1 
ATOM   166  N N   . LEU A 1 39  ? 234.833 214.991 156.403 1.00 54.38  ? 39   LEU D N   1 
ATOM   167  C CA  . LEU A 1 39  ? 235.753 215.492 155.384 1.00 54.38  ? 39   LEU D CA  1 
ATOM   168  C C   . LEU A 1 39  ? 235.273 216.824 154.811 1.00 54.38  ? 39   LEU D C   1 
ATOM   169  O O   . LEU A 1 39  ? 236.058 217.771 154.667 1.00 54.38  ? 39   LEU D O   1 
ATOM   170  C CB  . LEU A 1 39  ? 235.934 214.454 154.279 1.00 54.38  ? 39   LEU D CB  1 
ATOM   171  C CG  . LEU A 1 39  ? 237.138 214.714 153.372 1.00 54.38  ? 39   LEU D CG  1 
ATOM   172  C CD1 . LEU A 1 39  ? 238.368 215.040 154.203 1.00 54.38  ? 39   LEU D CD1 1 
ATOM   173  C CD2 . LEU A 1 39  ? 237.401 213.511 152.497 1.00 54.38  ? 39   LEU D CD2 1 
ATOM   174  N N   . PHE A 1 40  ? 233.980 216.920 154.490 1.00 52.60  ? 40   PHE D N   1 
ATOM   175  C CA  . PHE A 1 40  ? 233.419 218.170 153.997 1.00 52.60  ? 40   PHE D CA  1 
ATOM   176  C C   . PHE A 1 40  ? 233.430 219.248 155.069 1.00 52.60  ? 40   PHE D C   1 
ATOM   177  O O   . PHE A 1 40  ? 233.576 220.430 154.747 1.00 52.60  ? 40   PHE D O   1 
ATOM   178  C CB  . PHE A 1 40  ? 231.996 217.938 153.487 1.00 52.60  ? 40   PHE D CB  1 
ATOM   179  C CG  . PHE A 1 40  ? 231.321 219.181 152.980 1.00 52.60  ? 40   PHE D CG  1 
ATOM   180  C CD1 . PHE A 1 40  ? 231.577 219.652 151.704 1.00 52.60  ? 40   PHE D CD1 1 
ATOM   181  C CD2 . PHE A 1 40  ? 230.425 219.874 153.778 1.00 52.60  ? 40   PHE D CD2 1 
ATOM   182  C CE1 . PHE A 1 40  ? 230.956 220.793 151.234 1.00 52.60  ? 40   PHE D CE1 1 
ATOM   183  C CE2 . PHE A 1 40  ? 229.802 221.015 153.314 1.00 52.60  ? 40   PHE D CE2 1 
ATOM   184  C CZ  . PHE A 1 40  ? 230.068 221.475 152.040 1.00 52.60  ? 40   PHE D CZ  1 
ATOM   185  N N   . TYR A 1 41  ? 233.291 218.870 156.342 1.00 53.18  ? 41   TYR D N   1 
ATOM   186  C CA  . TYR A 1 41  ? 233.391 219.858 157.409 1.00 53.18  ? 41   TYR D CA  1 
ATOM   187  C C   . TYR A 1 41  ? 234.793 220.448 157.479 1.00 53.18  ? 41   TYR D C   1 
ATOM   188  O O   . TYR A 1 41  ? 234.954 221.664 157.630 1.00 53.18  ? 41   TYR D O   1 
ATOM   189  C CB  . TYR A 1 41  ? 233.000 219.230 158.746 1.00 53.18  ? 41   TYR D CB  1 
ATOM   190  C CG  . TYR A 1 41  ? 233.008 220.199 159.905 1.00 53.18  ? 41   TYR D CG  1 
ATOM   191  C CD1 . TYR A 1 41  ? 232.024 221.170 160.028 1.00 53.18  ? 41   TYR D CD1 1 
ATOM   192  C CD2 . TYR A 1 41  ? 233.993 220.137 160.880 1.00 53.18  ? 41   TYR D CD2 1 
ATOM   193  C CE1 . TYR A 1 41  ? 232.025 222.056 161.087 1.00 53.18  ? 41   TYR D CE1 1 
ATOM   194  C CE2 . TYR A 1 41  ? 234.001 221.018 161.943 1.00 53.18  ? 41   TYR D CE2 1 
ATOM   195  C CZ  . TYR A 1 41  ? 233.016 221.977 162.040 1.00 53.18  ? 41   TYR D CZ  1 
ATOM   196  O OH  . TYR A 1 41  ? 233.019 222.857 163.097 1.00 53.18  ? 41   TYR D OH  1 
ATOM   197  N N   . GLN A 1 42  ? 235.820 219.603 157.358 1.00 54.56  ? 42   GLN D N   1 
ATOM   198  C CA  . GLN A 1 42  ? 237.189 220.115 157.338 1.00 54.56  ? 42   GLN D CA  1 
ATOM   199  C C   . GLN A 1 42  ? 237.435 220.988 156.111 1.00 54.56  ? 42   GLN D C   1 
ATOM   200  O O   . GLN A 1 42  ? 238.084 222.039 156.205 1.00 54.56  ? 42   GLN D O   1 
ATOM   201  C CB  . GLN A 1 42  ? 238.186 218.959 157.386 1.00 54.56  ? 42   GLN D CB  1 
ATOM   202  C CG  . GLN A 1 42  ? 238.184 218.195 158.699 1.00 54.56  ? 42   GLN D CG  1 
ATOM   203  C CD  . GLN A 1 42  ? 239.253 217.122 158.749 1.00 54.56  ? 42   GLN D CD  1 
ATOM   204  O OE1 . GLN A 1 42  ? 239.985 216.913 157.782 1.00 54.56  ? 42   GLN D OE1 1 
ATOM   205  N NE2 . GLN A 1 42  ? 239.350 216.436 159.882 1.00 54.56  ? 42   GLN D NE2 1 
ATOM   206  N N   . SER A 1 43  ? 236.919 220.571 154.951 1.00 53.90  ? 43   SER D N   1 
ATOM   207  C CA  . SER A 1 43  ? 237.087 221.372 153.741 1.00 53.90  ? 43   SER D CA  1 
ATOM   208  C C   . SER A 1 43  ? 236.407 222.730 153.876 1.00 53.90  ? 43   SER D C   1 
ATOM   209  O O   . SER A 1 43  ? 236.962 223.758 153.467 1.00 53.90  ? 43   SER D O   1 
ATOM   210  C CB  . SER A 1 43  ? 236.537 220.615 152.532 1.00 53.90  ? 43   SER D CB  1 
ATOM   211  O OG  . SER A 1 43  ? 236.671 221.381 151.347 1.00 53.90  ? 43   SER D OG  1 
ATOM   212  N N   . SER A 1 44  ? 235.208 222.757 154.460 1.00 54.32  ? 44   SER D N   1 
ATOM   213  C CA  . SER A 1 44  ? 234.499 224.015 154.651 1.00 54.32  ? 44   SER D CA  1 
ATOM   214  C C   . SER A 1 44  ? 235.183 224.892 155.689 1.00 54.32  ? 44   SER D C   1 
ATOM   215  O O   . SER A 1 44  ? 235.186 226.119 155.551 1.00 54.32  ? 44   SER D O   1 
ATOM   216  C CB  . SER A 1 44  ? 233.049 223.744 155.048 1.00 54.32  ? 44   SER D CB  1 
ATOM   217  O OG  . SER A 1 44  ? 232.369 223.027 154.033 1.00 54.32  ? 44   SER D OG  1 
ATOM   218  N N   . LEU A 1 45  ? 235.771 224.292 156.728 1.00 54.80  ? 45   LEU D N   1 
ATOM   219  C CA  . LEU A 1 45  ? 236.556 225.074 157.678 1.00 54.80  ? 45   LEU D CA  1 
ATOM   220  C C   . LEU A 1 45  ? 237.756 225.716 156.997 1.00 54.80  ? 45   LEU D C   1 
ATOM   221  O O   . LEU A 1 45  ? 238.071 226.885 157.249 1.00 54.80  ? 45   LEU D O   1 
ATOM   222  C CB  . LEU A 1 45  ? 237.013 224.196 158.842 1.00 54.80  ? 45   LEU D CB  1 
ATOM   223  C CG  . LEU A 1 45  ? 235.982 223.842 159.912 1.00 54.80  ? 45   LEU D CG  1 
ATOM   224  C CD1 . LEU A 1 45  ? 236.657 223.109 161.060 1.00 54.80  ? 45   LEU D CD1 1 
ATOM   225  C CD2 . LEU A 1 45  ? 235.276 225.090 160.411 1.00 54.80  ? 45   LEU D CD2 1 
ATOM   226  N N   . ALA A 1 46  ? 238.441 224.964 156.131 1.00 55.96  ? 46   ALA D N   1 
ATOM   227  C CA  . ALA A 1 46  ? 239.566 225.534 155.395 1.00 55.96  ? 46   ALA D CA  1 
ATOM   228  C C   . ALA A 1 46  ? 239.111 226.667 154.482 1.00 55.96  ? 46   ALA D C   1 
ATOM   229  O O   . ALA A 1 46  ? 239.763 227.718 154.408 1.00 55.96  ? 46   ALA D O   1 
ATOM   230  C CB  . ALA A 1 46  ? 240.273 224.444 154.589 1.00 55.96  ? 46   ALA D CB  1 
ATOM   231  N N   . SER A 1 47  ? 237.988 226.476 153.786 1.00 55.00  ? 47   SER D N   1 
ATOM   232  C CA  . SER A 1 47  ? 237.481 227.519 152.899 1.00 55.00  ? 47   SER D CA  1 
ATOM   233  C C   . SER A 1 47  ? 237.074 228.763 153.681 1.00 55.00  ? 47   SER D C   1 
ATOM   234  O O   . SER A 1 47  ? 237.281 229.892 153.220 1.00 55.00  ? 47   SER D O   1 
ATOM   235  C CB  . SER A 1 47  ? 236.305 226.986 152.082 1.00 55.00  ? 47   SER D CB  1 
ATOM   236  O OG  . SER A 1 47  ? 235.858 227.948 151.142 1.00 55.00  ? 47   SER D OG  1 
ATOM   237  N N   . TRP A 1 48  ? 236.498 228.577 154.871 1.00 55.91  ? 48   TRP D N   1 
ATOM   238  C CA  . TRP A 1 48  ? 236.117 229.714 155.702 1.00 55.91  ? 48   TRP D CA  1 
ATOM   239  C C   . TRP A 1 48  ? 237.343 230.450 156.226 1.00 55.91  ? 48   TRP D C   1 
ATOM   240  O O   . TRP A 1 48  ? 237.362 231.686 156.266 1.00 55.91  ? 48   TRP D O   1 
ATOM   241  C CB  . TRP A 1 48  ? 235.236 229.242 156.859 1.00 55.91  ? 48   TRP D CB  1 
ATOM   242  C CG  . TRP A 1 48  ? 234.983 230.289 157.902 1.00 55.91  ? 48   TRP D CG  1 
ATOM   243  C CD1 . TRP A 1 48  ? 235.705 230.503 159.041 1.00 55.91  ? 48   TRP D CD1 1 
ATOM   244  C CD2 . TRP A 1 48  ? 233.932 231.262 157.907 1.00 55.91  ? 48   TRP D CD2 1 
ATOM   245  N NE1 . TRP A 1 48  ? 235.171 231.549 159.752 1.00 55.91  ? 48   TRP D NE1 1 
ATOM   246  C CE2 . TRP A 1 48  ? 234.081 232.033 159.077 1.00 55.91  ? 48   TRP D CE2 1 
ATOM   247  C CE3 . TRP A 1 48  ? 232.880 231.558 157.035 1.00 55.91  ? 48   TRP D CE3 1 
ATOM   248  C CZ2 . TRP A 1 48  ? 233.219 233.079 159.396 1.00 55.91  ? 48   TRP D CZ2 1 
ATOM   249  C CZ3 . TRP A 1 48  ? 232.026 232.597 157.354 1.00 55.91  ? 48   TRP D CZ3 1 
ATOM   250  C CH2 . TRP A 1 48  ? 232.200 233.344 158.525 1.00 55.91  ? 48   TRP D CH2 1 
ATOM   251  N N   . ASN A 1 49  ? 238.374 229.708 156.637 1.00 59.24  ? 49   ASN D N   1 
ATOM   252  C CA  . ASN A 1 49  ? 239.606 230.348 157.084 1.00 59.24  ? 49   ASN D CA  1 
ATOM   253  C C   . ASN A 1 49  ? 240.293 231.093 155.947 1.00 59.24  ? 49   ASN D C   1 
ATOM   254  O O   . ASN A 1 49  ? 240.952 232.111 156.185 1.00 59.24  ? 49   ASN D O   1 
ATOM   255  C CB  . ASN A 1 49  ? 240.552 229.311 157.688 1.00 59.24  ? 49   ASN D CB  1 
ATOM   256  C CG  . ASN A 1 49  ? 240.026 228.727 158.984 1.00 59.24  ? 49   ASN D CG  1 
ATOM   257  O OD1 . ASN A 1 49  ? 239.327 229.399 159.742 1.00 59.24  ? 49   ASN D OD1 1 
ATOM   258  N ND2 . ASN A 1 49  ? 240.361 227.469 159.245 1.00 59.24  ? 49   ASN D ND2 1 
ATOM   259  N N   . TYR A 1 50  ? 240.151 230.607 154.712 1.00 60.89  ? 50   TYR D N   1 
ATOM   260  C CA  . TYR A 1 50  ? 240.737 231.320 153.582 1.00 60.89  ? 50   TYR D CA  1 
ATOM   261  C C   . TYR A 1 50  ? 239.936 232.567 153.220 1.00 60.89  ? 50   TYR D C   1 
ATOM   262  O O   . TYR A 1 50  ? 240.521 233.615 152.925 1.00 60.89  ? 50   TYR D O   1 
ATOM   263  C CB  . TYR A 1 50  ? 240.848 230.400 152.367 1.00 60.89  ? 50   TYR D CB  1 
ATOM   264  C CG  . TYR A 1 50  ? 241.180 231.139 151.090 1.00 60.89  ? 50   TYR D CG  1 
ATOM   265  C CD1 . TYR A 1 50  ? 242.456 231.636 150.865 1.00 60.89  ? 50   TYR D CD1 1 
ATOM   266  C CD2 . TYR A 1 50  ? 240.215 231.346 150.113 1.00 60.89  ? 50   TYR D CD2 1 
ATOM   267  C CE1 . TYR A 1 50  ? 242.762 232.317 149.702 1.00 60.89  ? 50   TYR D CE1 1 
ATOM   268  C CE2 . TYR A 1 50  ? 240.512 232.024 148.947 1.00 60.89  ? 50   TYR D CE2 1 
ATOM   269  C CZ  . TYR A 1 50  ? 241.787 232.507 148.746 1.00 60.89  ? 50   TYR D CZ  1 
ATOM   270  O OH  . TYR A 1 50  ? 242.088 233.182 147.586 1.00 60.89  ? 50   TYR D OH  1 
ATOM   271  N N   . ASN A 1 51  ? 238.604 232.475 153.234 1.00 59.19  ? 51   ASN D N   1 
ATOM   272  C CA  . ASN A 1 51  ? 237.788 233.611 152.816 1.00 59.19  ? 51   ASN D CA  1 
ATOM   273  C C   . ASN A 1 51  ? 237.816 234.731 153.849 1.00 59.19  ? 51   ASN D C   1 
ATOM   274  O O   . ASN A 1 51  ? 237.815 235.914 153.489 1.00 59.19  ? 51   ASN D O   1 
ATOM   275  C CB  . ASN A 1 51  ? 236.352 233.159 152.549 1.00 59.19  ? 51   ASN D CB  1 
ATOM   276  C CG  . ASN A 1 51  ? 236.232 232.316 151.294 1.00 59.19  ? 51   ASN D CG  1 
ATOM   277  O OD1 . ASN A 1 51  ? 237.169 231.617 150.910 1.00 59.19  ? 51   ASN D OD1 1 
ATOM   278  N ND2 . ASN A 1 51  ? 235.078 232.387 150.643 1.00 59.19  ? 51   ASN D ND2 1 
ATOM   279  N N   . THR A 1 52  ? 237.839 234.383 155.136 1.00 61.50  ? 52   THR D N   1 
ATOM   280  C CA  . THR A 1 52  ? 237.914 235.389 156.186 1.00 61.50  ? 52   THR D CA  1 
ATOM   281  C C   . THR A 1 52  ? 239.338 235.850 156.465 1.00 61.50  ? 52   THR D C   1 
ATOM   282  O O   . THR A 1 52  ? 239.524 236.815 157.214 1.00 61.50  ? 52   THR D O   1 
ATOM   283  C CB  . THR A 1 52  ? 237.292 234.855 157.479 1.00 61.50  ? 52   THR D CB  1 
ATOM   284  O OG1 . THR A 1 52  ? 237.983 233.669 157.891 1.00 61.50  ? 52   THR D OG1 1 
ATOM   285  C CG2 . THR A 1 52  ? 235.822 234.532 157.268 1.00 61.50  ? 52   THR D CG2 1 
ATOM   286  N N   . ASN A 1 53  ? 240.341 235.191 155.884 1.00 67.38  ? 53   ASN D N   1 
ATOM   287  C CA  . ASN A 1 53  ? 241.740 235.541 156.126 1.00 67.38  ? 53   ASN D CA  1 
ATOM   288  C C   . ASN A 1 53  ? 242.532 235.100 154.898 1.00 67.38  ? 53   ASN D C   1 
ATOM   289  O O   . ASN A 1 53  ? 242.834 233.913 154.746 1.00 67.38  ? 53   ASN D O   1 
ATOM   290  C CB  . ASN A 1 53  ? 242.253 234.877 157.397 1.00 67.38  ? 53   ASN D CB  1 
ATOM   291  C CG  . ASN A 1 53  ? 243.598 235.419 157.844 1.00 67.38  ? 53   ASN D CG  1 
ATOM   292  O OD1 . ASN A 1 53  ? 244.317 236.056 157.075 1.00 67.38  ? 53   ASN D OD1 1 
ATOM   293  N ND2 . ASN A 1 53  ? 243.945 235.161 159.100 1.00 67.38  ? 53   ASN D ND2 1 
ATOM   294  N N   . ILE A 1 54  ? 242.862 236.054 154.034 1.00 66.74  ? 54   ILE D N   1 
ATOM   295  C CA  . ILE A 1 54  ? 243.599 235.769 152.807 1.00 66.74  ? 54   ILE D CA  1 
ATOM   296  C C   . ILE A 1 54  ? 245.089 235.797 153.120 1.00 66.74  ? 54   ILE D C   1 
ATOM   297  O O   . ILE A 1 54  ? 245.614 236.803 153.611 1.00 66.74  ? 54   ILE D O   1 
ATOM   298  C CB  . ILE A 1 54  ? 243.247 236.769 151.694 1.00 66.74  ? 54   ILE D CB  1 
ATOM   299  C CG1 . ILE A 1 54  ? 241.945 236.370 150.992 1.00 66.74  ? 54   ILE D CG1 1 
ATOM   300  C CG2 . ILE A 1 54  ? 244.374 236.859 150.675 1.00 66.74  ? 54   ILE D CG2 1 
ATOM   301  C CD1 . ILE A 1 54  ? 240.687 236.693 151.767 1.00 66.74  ? 54   ILE D CD1 1 
ATOM   302  N N   . THR A 1 55  ? 245.767 234.688 152.846 1.00 69.26  ? 55   THR D N   1 
ATOM   303  C CA  . THR A 1 55  ? 247.209 234.576 153.030 1.00 69.26  ? 55   THR D CA  1 
ATOM   304  C C   . THR A 1 55  ? 247.705 233.444 152.136 1.00 69.26  ? 55   THR D C   1 
ATOM   305  O O   . THR A 1 55  ? 246.942 232.876 151.348 1.00 69.26  ? 55   THR D O   1 
ATOM   306  C CB  . THR A 1 55  ? 247.565 234.346 154.503 1.00 69.26  ? 55   THR D CB  1 
ATOM   307  O OG1 . THR A 1 55  ? 248.989 234.312 154.653 1.00 69.26  ? 55   THR D OG1 1 
ATOM   308  C CG2 . THR A 1 55  ? 246.982 233.032 154.992 1.00 69.26  ? 55   THR D CG2 1 
ATOM   309  N N   . GLU A 1 56  ? 248.989 233.114 152.258 1.00 71.88  ? 56   GLU D N   1 
ATOM   310  C CA  . GLU A 1 56  ? 249.579 232.055 151.449 1.00 71.88  ? 56   GLU D CA  1 
ATOM   311  C C   . GLU A 1 56  ? 249.417 230.672 152.062 1.00 71.88  ? 56   GLU D C   1 
ATOM   312  O O   . GLU A 1 56  ? 249.571 229.674 151.349 1.00 71.88  ? 56   GLU D O   1 
ATOM   313  C CB  . GLU A 1 56  ? 251.068 232.334 151.218 1.00 71.88  ? 56   GLU D CB  1 
ATOM   314  C CG  . GLU A 1 56  ? 251.348 233.602 150.428 1.00 71.88  ? 56   GLU D CG  1 
ATOM   315  C CD  . GLU A 1 56  ? 250.874 233.515 148.990 1.00 71.88  ? 56   GLU D CD  1 
ATOM   316  O OE1 . GLU A 1 56  ? 250.734 232.386 148.473 1.00 71.88  ? 56   GLU D OE1 1 
ATOM   317  O OE2 . GLU A 1 56  ? 250.642 234.576 148.375 1.00 71.88  ? 56   GLU D OE2 1 
ATOM   318  N N   . GLU A 1 57  ? 249.111 230.585 153.356 1.00 70.87  ? 57   GLU D N   1 
ATOM   319  C CA  . GLU A 1 57  ? 248.929 229.295 154.010 1.00 70.87  ? 57   GLU D CA  1 
ATOM   320  C C   . GLU A 1 57  ? 247.482 228.824 153.962 1.00 70.87  ? 57   GLU D C   1 
ATOM   321  O O   . GLU A 1 57  ? 247.224 227.627 153.781 1.00 70.87  ? 57   GLU D O   1 
ATOM   322  C CB  . GLU A 1 57  ? 249.402 229.372 155.465 1.00 70.87  ? 57   GLU D CB  1 
ATOM   323  C CG  . GLU A 1 57  ? 250.857 229.787 155.627 1.00 70.87  ? 57   GLU D CG  1 
ATOM   324  C CD  . GLU A 1 57  ? 251.828 228.738 155.119 1.00 70.87  ? 57   GLU D CD  1 
ATOM   325  O OE1 . GLU A 1 57  ? 251.441 227.553 155.036 1.00 70.87  ? 57   GLU D OE1 1 
ATOM   326  O OE2 . GLU A 1 57  ? 252.980 229.099 154.801 1.00 70.87  ? 57   GLU D OE2 1 
ATOM   327  N N   . ASN A 1 58  ? 246.530 229.746 154.124 1.00 65.61  ? 58   ASN D N   1 
ATOM   328  C CA  . ASN A 1 58  ? 245.122 229.370 154.074 1.00 65.61  ? 58   ASN D CA  1 
ATOM   329  C C   . ASN A 1 58  ? 244.731 228.872 152.688 1.00 65.61  ? 58   ASN D C   1 
ATOM   330  O O   . ASN A 1 58  ? 243.935 227.936 152.564 1.00 65.61  ? 58   ASN D O   1 
ATOM   331  C CB  . ASN A 1 58  ? 244.245 230.551 154.489 1.00 65.61  ? 58   ASN D CB  1 
ATOM   332  C CG  . ASN A 1 58  ? 244.375 230.883 155.962 1.00 65.61  ? 58   ASN D CG  1 
ATOM   333  O OD1 . ASN A 1 58  ? 244.753 230.035 156.770 1.00 65.61  ? 58   ASN D OD1 1 
ATOM   334  N ND2 . ASN A 1 58  ? 244.055 232.121 156.320 1.00 65.61  ? 58   ASN D ND2 1 
ATOM   335  N N   . VAL A 1 59  ? 245.288 229.476 151.636 1.00 65.13  ? 59   VAL D N   1 
ATOM   336  C CA  . VAL A 1 59  ? 244.972 229.028 150.283 1.00 65.13  ? 59   VAL D CA  1 
ATOM   337  C C   . VAL A 1 59  ? 245.515 227.623 150.045 1.00 65.13  ? 59   VAL D C   1 
ATOM   338  O O   . VAL A 1 59  ? 244.851 226.785 149.425 1.00 65.13  ? 59   VAL D O   1 
ATOM   339  C CB  . VAL A 1 59  ? 245.500 230.036 149.243 1.00 65.13  ? 59   VAL D CB  1 
ATOM   340  C CG1 . VAL A 1 59  ? 246.994 230.268 149.413 1.00 65.13  ? 59   VAL D CG1 1 
ATOM   341  C CG2 . VAL A 1 59  ? 245.182 229.566 147.831 1.00 65.13  ? 59   VAL D CG2 1 
ATOM   342  N N   . GLN A 1 60  ? 246.714 227.332 150.557 1.00 67.15  ? 60   GLN D N   1 
ATOM   343  C CA  . GLN A 1 60  ? 247.270 225.990 150.412 1.00 67.15  ? 60   GLN D CA  1 
ATOM   344  C C   . GLN A 1 60  ? 246.458 224.969 151.198 1.00 67.15  ? 60   GLN D C   1 
ATOM   345  O O   . GLN A 1 60  ? 246.204 223.861 150.710 1.00 67.15  ? 60   GLN D O   1 
ATOM   346  C CB  . GLN A 1 60  ? 248.731 225.972 150.860 1.00 67.15  ? 60   GLN D CB  1 
ATOM   347  C CG  . GLN A 1 60  ? 249.666 226.763 149.963 1.00 67.15  ? 60   GLN D CG  1 
ATOM   348  C CD  . GLN A 1 60  ? 251.099 226.742 150.455 1.00 67.15  ? 60   GLN D CD  1 
ATOM   349  O OE1 . GLN A 1 60  ? 251.403 226.145 151.488 1.00 67.15  ? 60   GLN D OE1 1 
ATOM   350  N NE2 . GLN A 1 60  ? 251.988 227.395 149.717 1.00 67.15  ? 60   GLN D NE2 1 
ATOM   351  N N   . ASN A 1 61  ? 246.039 225.325 152.415 1.00 64.57  ? 61   ASN D N   1 
ATOM   352  C CA  . ASN A 1 61  ? 245.206 224.419 153.199 1.00 64.57  ? 61   ASN D CA  1 
ATOM   353  C C   . ASN A 1 61  ? 243.875 224.156 152.505 1.00 64.57  ? 61   ASN D C   1 
ATOM   354  O O   . ASN A 1 61  ? 243.399 223.014 152.468 1.00 64.57  ? 61   ASN D O   1 
ATOM   355  C CB  . ASN A 1 61  ? 244.977 224.990 154.599 1.00 64.57  ? 61   ASN D CB  1 
ATOM   356  C CG  . ASN A 1 61  ? 246.262 225.120 155.391 1.00 64.57  ? 61   ASN D CG  1 
ATOM   357  O OD1 . ASN A 1 61  ? 247.213 224.368 155.182 1.00 64.57  ? 61   ASN D OD1 1 
ATOM   358  N ND2 . ASN A 1 61  ? 246.295 226.078 156.310 1.00 64.57  ? 61   ASN D ND2 1 
ATOM   359  N N   . MET A 1 62  ? 243.266 225.201 151.939 1.00 61.63  ? 62   MET D N   1 
ATOM   360  C CA  . MET A 1 62  ? 242.003 225.031 151.231 1.00 61.63  ? 62   MET D CA  1 
ATOM   361  C C   . MET A 1 62  ? 242.178 224.160 149.995 1.00 61.63  ? 62   MET D C   1 
ATOM   362  O O   . MET A 1 62  ? 241.334 223.305 149.707 1.00 61.63  ? 62   MET D O   1 
ATOM   363  C CB  . MET A 1 62  ? 241.426 226.394 150.847 1.00 61.63  ? 62   MET D CB  1 
ATOM   364  C CG  . MET A 1 62  ? 240.086 226.318 150.134 1.00 61.63  ? 62   MET D CG  1 
ATOM   365  S SD  . MET A 1 62  ? 239.524 227.918 149.522 1.00 61.63  ? 62   MET D SD  1 
ATOM   366  C CE  . MET A 1 62  ? 240.807 228.291 148.330 1.00 61.63  ? 62   MET D CE  1 
ATOM   367  N N   . ASN A 1 63  ? 243.271 224.359 149.253 1.00 61.59  ? 63   ASN D N   1 
ATOM   368  C CA  . ASN A 1 63  ? 243.522 223.534 148.076 1.00 61.59  ? 63   ASN D CA  1 
ATOM   369  C C   . ASN A 1 63  ? 243.729 222.074 148.459 1.00 61.59  ? 63   ASN D C   1 
ATOM   370  O O   . ASN A 1 63  ? 243.209 221.171 147.793 1.00 61.59  ? 63   ASN D O   1 
ATOM   371  C CB  . ASN A 1 63  ? 244.732 224.066 147.308 1.00 61.59  ? 63   ASN D CB  1 
ATOM   372  C CG  . ASN A 1 63  ? 244.470 225.419 146.675 1.00 61.59  ? 63   ASN D CG  1 
ATOM   373  O OD1 . ASN A 1 63  ? 243.338 225.740 146.316 1.00 61.59  ? 63   ASN D OD1 1 
ATOM   374  N ND2 . ASN A 1 63  ? 245.520 226.219 146.534 1.00 61.59  ? 63   ASN D ND2 1 
ATOM   375  N N   . ASN A 1 64  ? 244.482 221.822 149.533 1.00 61.42  ? 64   ASN D N   1 
ATOM   376  C CA  . ASN A 1 64  ? 244.700 220.448 149.978 1.00 61.42  ? 64   ASN D CA  1 
ATOM   377  C C   . ASN A 1 64  ? 243.391 219.795 150.405 1.00 61.42  ? 64   ASN D C   1 
ATOM   378  O O   . ASN A 1 64  ? 243.105 218.647 150.039 1.00 61.42  ? 64   ASN D O   1 
ATOM   379  C CB  . ASN A 1 64  ? 245.715 220.421 151.121 1.00 61.42  ? 64   ASN D CB  1 
ATOM   380  C CG  . ASN A 1 64  ? 247.082 220.917 150.698 1.00 61.42  ? 64   ASN D CG  1 
ATOM   381  O OD1 . ASN A 1 64  ? 247.469 220.793 149.536 1.00 61.42  ? 64   ASN D OD1 1 
ATOM   382  N ND2 . ASN A 1 64  ? 247.824 221.485 151.642 1.00 61.42  ? 64   ASN D ND2 1 
ATOM   383  N N   . ALA A 1 65  ? 242.579 220.518 151.183 1.00 57.57  ? 65   ALA D N   1 
ATOM   384  C CA  . ALA A 1 65  ? 241.299 219.972 151.623 1.00 57.57  ? 65   ALA D CA  1 
ATOM   385  C C   . ALA A 1 65  ? 240.377 219.703 150.440 1.00 57.57  ? 65   ALA D C   1 
ATOM   386  O O   . ALA A 1 65  ? 239.691 218.675 150.400 1.00 57.57  ? 65   ALA D O   1 
ATOM   387  C CB  . ALA A 1 65  ? 240.637 220.924 152.618 1.00 57.57  ? 65   ALA D CB  1 
ATOM   388  N N   . GLY A 1 66  ? 240.357 220.610 149.461 1.00 57.88  ? 66   GLY D N   1 
ATOM   389  C CA  . GLY A 1 66  ? 239.517 220.405 148.294 1.00 57.88  ? 66   GLY D CA  1 
ATOM   390  C C   . GLY A 1 66  ? 239.966 219.228 147.451 1.00 57.88  ? 66   GLY D C   1 
ATOM   391  O O   . GLY A 1 66  ? 239.138 218.463 146.950 1.00 57.88  ? 66   GLY D O   1 
ATOM   392  N N   . ASP A 1 67  ? 241.280 219.062 147.284 1.00 59.44  ? 67   ASP D N   1 
ATOM   393  C CA  . ASP A 1 67  ? 241.786 217.915 146.538 1.00 59.44  ? 67   ASP D CA  1 
ATOM   394  C C   . ASP A 1 67  ? 241.456 216.610 147.251 1.00 59.44  ? 67   ASP D C   1 
ATOM   395  O O   . ASP A 1 67  ? 241.067 215.625 146.612 1.00 59.44  ? 67   ASP D O   1 
ATOM   396  C CB  . ASP A 1 67  ? 243.294 218.047 146.326 1.00 59.44  ? 67   ASP D CB  1 
ATOM   397  C CG  . ASP A 1 67  ? 243.660 219.246 145.477 1.00 59.44  ? 67   ASP D CG  1 
ATOM   398  O OD1 . ASP A 1 67  ? 242.742 219.988 145.067 1.00 59.44  ? 67   ASP D OD1 1 
ATOM   399  O OD2 . ASP A 1 67  ? 244.865 219.449 145.219 1.00 59.44  ? 67   ASP D OD2 1 
ATOM   400  N N   . LYS A 1 68  ? 241.599 216.586 148.580 1.00 56.78  ? 68   LYS D N   1 
ATOM   401  C CA  . LYS A 1 68  ? 241.249 215.387 149.333 1.00 56.78  ? 68   LYS D CA  1 
ATOM   402  C C   . LYS A 1 68  ? 239.762 215.075 149.211 1.00 56.78  ? 68   LYS D C   1 
ATOM   403  O O   . LYS A 1 68  ? 239.376 213.915 149.021 1.00 56.78  ? 68   LYS D O   1 
ATOM   404  C CB  . LYS A 1 68  ? 241.647 215.554 150.799 1.00 56.78  ? 68   LYS D CB  1 
ATOM   405  C CG  . LYS A 1 68  ? 241.405 214.322 151.653 1.00 56.78  ? 68   LYS D CG  1 
ATOM   406  C CD  . LYS A 1 68  ? 241.894 214.534 153.076 1.00 56.78  ? 68   LYS D CD  1 
ATOM   407  C CE  . LYS A 1 68  ? 243.381 214.843 153.108 1.00 56.78  ? 68   LYS D CE  1 
ATOM   408  N NZ  . LYS A 1 68  ? 243.874 215.054 154.496 1.00 56.78  ? 68   LYS D NZ  1 
ATOM   409  N N   . TRP A 1 69  ? 238.913 216.103 149.302 1.00 53.73  ? 69   TRP D N   1 
ATOM   410  C CA  . TRP A 1 69  ? 237.474 215.896 149.177 1.00 53.73  ? 69   TRP D CA  1 
ATOM   411  C C   . TRP A 1 69  ? 237.102 215.405 147.783 1.00 53.73  ? 69   TRP D C   1 
ATOM   412  O O   . TRP A 1 69  ? 236.240 214.532 147.634 1.00 53.73  ? 69   TRP D O   1 
ATOM   413  C CB  . TRP A 1 69  ? 236.738 217.193 149.514 1.00 53.73  ? 69   TRP D CB  1 
ATOM   414  C CG  . TRP A 1 69  ? 235.269 217.163 149.233 1.00 53.73  ? 69   TRP D CG  1 
ATOM   415  C CD1 . TRP A 1 69  ? 234.613 217.829 148.240 1.00 53.73  ? 69   TRP D CD1 1 
ATOM   416  C CD2 . TRP A 1 69  ? 234.271 216.433 149.954 1.00 53.73  ? 69   TRP D CD2 1 
ATOM   417  N NE1 . TRP A 1 69  ? 233.268 217.560 148.298 1.00 53.73  ? 69   TRP D NE1 1 
ATOM   418  C CE2 . TRP A 1 69  ? 233.032 216.704 149.341 1.00 53.73  ? 69   TRP D CE2 1 
ATOM   419  C CE3 . TRP A 1 69  ? 234.304 215.576 151.058 1.00 53.73  ? 69   TRP D CE3 1 
ATOM   420  C CZ2 . TRP A 1 69  ? 231.838 216.149 149.794 1.00 53.73  ? 69   TRP D CZ2 1 
ATOM   421  C CZ3 . TRP A 1 69  ? 233.118 215.027 151.506 1.00 53.73  ? 69   TRP D CZ3 1 
ATOM   422  C CH2 . TRP A 1 69  ? 231.902 215.315 150.876 1.00 53.73  ? 69   TRP D CH2 1 
ATOM   423  N N   . SER A 1 70  ? 237.754 215.942 146.749 1.00 54.24  ? 70   SER D N   1 
ATOM   424  C CA  . SER A 1 70  ? 237.469 215.508 145.386 1.00 54.24  ? 70   SER D CA  1 
ATOM   425  C C   . SER A 1 70  ? 237.905 214.065 145.161 1.00 54.24  ? 70   SER D C   1 
ATOM   426  O O   . SER A 1 70  ? 237.180 213.283 144.533 1.00 54.24  ? 70   SER D O   1 
ATOM   427  C CB  . SER A 1 70  ? 238.154 216.438 144.385 1.00 54.24  ? 70   SER D CB  1 
ATOM   428  O OG  . SER A 1 70  ? 237.711 217.774 144.548 1.00 54.24  ? 70   SER D OG  1 
ATOM   429  N N   . ALA A 1 71  ? 239.086 213.694 145.663 1.00 54.03  ? 71   ALA D N   1 
ATOM   430  C CA  . ALA A 1 71  ? 239.534 212.310 145.542 1.00 54.03  ? 71   ALA D CA  1 
ATOM   431  C C   . ALA A 1 71  ? 238.601 211.366 146.289 1.00 54.03  ? 71   ALA D C   1 
ATOM   432  O O   . ALA A 1 71  ? 238.285 210.273 145.800 1.00 54.03  ? 71   ALA D O   1 
ATOM   433  C CB  . ALA A 1 71  ? 240.966 212.173 146.058 1.00 54.03  ? 71   ALA D CB  1 
ATOM   434  N N   . PHE A 1 72  ? 238.144 211.774 147.475 1.00 53.30  ? 72   PHE D N   1 
ATOM   435  C CA  . PHE A 1 72  ? 237.204 210.954 148.230 1.00 53.30  ? 72   PHE D CA  1 
ATOM   436  C C   . PHE A 1 72  ? 235.892 210.783 147.477 1.00 53.30  ? 72   PHE D C   1 
ATOM   437  O O   . PHE A 1 72  ? 235.342 209.677 147.421 1.00 53.30  ? 72   PHE D O   1 
ATOM   438  C CB  . PHE A 1 72  ? 236.959 211.578 149.603 1.00 53.30  ? 72   PHE D CB  1 
ATOM   439  C CG  . PHE A 1 72  ? 235.964 210.833 150.444 1.00 53.30  ? 72   PHE D CG  1 
ATOM   440  C CD1 . PHE A 1 72  ? 234.643 211.245 150.505 1.00 53.30  ? 72   PHE D CD1 1 
ATOM   441  C CD2 . PHE A 1 72  ? 236.350 209.727 151.181 1.00 53.30  ? 72   PHE D CD2 1 
ATOM   442  C CE1 . PHE A 1 72  ? 233.726 210.564 151.280 1.00 53.30  ? 72   PHE D CE1 1 
ATOM   443  C CE2 . PHE A 1 72  ? 235.437 209.042 151.958 1.00 53.30  ? 72   PHE D CE2 1 
ATOM   444  C CZ  . PHE A 1 72  ? 234.123 209.462 152.007 1.00 53.30  ? 72   PHE D CZ  1 
ATOM   445  N N   . LEU A 1 73  ? 235.373 211.866 146.892 1.00 53.22  ? 73   LEU D N   1 
ATOM   446  C CA  . LEU A 1 73  ? 234.137 211.767 146.123 1.00 53.22  ? 73   LEU D CA  1 
ATOM   447  C C   . LEU A 1 73  ? 234.310 210.857 144.916 1.00 53.22  ? 73   LEU D C   1 
ATOM   448  O O   . LEU A 1 73  ? 233.420 210.061 144.598 1.00 53.22  ? 73   LEU D O   1 
ATOM   449  C CB  . LEU A 1 73  ? 233.673 213.154 145.681 1.00 53.22  ? 73   LEU D CB  1 
ATOM   450  C CG  . LEU A 1 73  ? 233.019 214.039 146.741 1.00 53.22  ? 73   LEU D CG  1 
ATOM   451  C CD1 . LEU A 1 73  ? 232.426 215.278 146.093 1.00 53.22  ? 73   LEU D CD1 1 
ATOM   452  C CD2 . LEU A 1 73  ? 231.956 213.267 147.504 1.00 53.22  ? 73   LEU D CD2 1 
ATOM   453  N N   . LYS A 1 74  ? 235.453 210.956 144.231 1.00 54.72  ? 74   LYS D N   1 
ATOM   454  C CA  . LYS A 1 74  ? 235.696 210.095 143.078 1.00 54.72  ? 74   LYS D CA  1 
ATOM   455  C C   . LYS A 1 74  ? 235.753 208.628 143.488 1.00 54.72  ? 74   LYS D C   1 
ATOM   456  O O   . LYS A 1 74  ? 235.158 207.767 142.827 1.00 54.72  ? 74   LYS D O   1 
ATOM   457  C CB  . LYS A 1 74  ? 236.989 210.512 142.378 1.00 54.72  ? 74   LYS D CB  1 
ATOM   458  C CG  . LYS A 1 74  ? 237.288 209.730 141.109 1.00 54.72  ? 74   LYS D CG  1 
ATOM   459  C CD  . LYS A 1 74  ? 238.553 210.234 140.434 1.00 54.72  ? 74   LYS D CD  1 
ATOM   460  C CE  . LYS A 1 74  ? 239.759 210.097 141.349 1.00 54.72  ? 74   LYS D CE  1 
ATOM   461  N NZ  . LYS A 1 74  ? 240.001 208.681 141.740 1.00 54.72  ? 74   LYS D NZ  1 
ATOM   462  N N   . GLU A 1 75  ? 236.460 208.326 144.581 1.00 55.80  ? 75   GLU D N   1 
ATOM   463  C CA  . GLU A 1 75  ? 236.536 206.945 145.051 1.00 55.80  ? 75   GLU D CA  1 
ATOM   464  C C   . GLU A 1 75  ? 235.164 206.424 145.464 1.00 55.80  ? 75   GLU D C   1 
ATOM   465  O O   . GLU A 1 75  ? 234.798 205.288 145.137 1.00 55.80  ? 75   GLU D O   1 
ATOM   466  C CB  . GLU A 1 75  ? 237.523 206.836 146.213 1.00 55.80  ? 75   GLU D CB  1 
ATOM   467  C CG  . GLU A 1 75  ? 238.970 207.083 145.825 1.00 55.80  ? 75   GLU D CG  1 
ATOM   468  C CD  . GLU A 1 75  ? 239.922 206.894 146.989 1.00 55.80  ? 75   GLU D CD  1 
ATOM   469  O OE1 . GLU A 1 75  ? 239.456 206.517 148.084 1.00 55.80  ? 75   GLU D OE1 1 
ATOM   470  O OE2 . GLU A 1 75  ? 241.137 207.121 146.808 1.00 55.80  ? 75   GLU D OE2 1 
ATOM   471  N N   . GLN A 1 76  ? 234.386 207.244 146.176 1.00 53.28  ? 76   GLN D N   1 
ATOM   472  C CA  . GLN A 1 76  ? 233.065 206.806 146.615 1.00 53.28  ? 76   GLN D CA  1 
ATOM   473  C C   . GLN A 1 76  ? 232.128 206.603 145.431 1.00 53.28  ? 76   GLN D C   1 
ATOM   474  O O   . GLN A 1 76  ? 231.296 205.692 145.446 1.00 53.28  ? 76   GLN D O   1 
ATOM   475  C CB  . GLN A 1 76  ? 232.478 207.812 147.604 1.00 53.28  ? 76   GLN D CB  1 
ATOM   476  C CG  . GLN A 1 76  ? 233.242 207.912 148.915 1.00 53.28  ? 76   GLN D CG  1 
ATOM   477  C CD  . GLN A 1 76  ? 233.212 206.625 149.715 1.00 53.28  ? 76   GLN D CD  1 
ATOM   478  O OE1 . GLN A 1 76  ? 232.251 205.861 149.647 1.00 53.28  ? 76   GLN D OE1 1 
ATOM   479  N NE2 . GLN A 1 76  ? 234.269 206.380 150.480 1.00 53.28  ? 76   GLN D NE2 1 
ATOM   480  N N   . SER A 1 77  ? 232.257 207.427 144.389 1.00 54.98  ? 77   SER D N   1 
ATOM   481  C CA  . SER A 1 77  ? 231.432 207.238 143.200 1.00 54.98  ? 77   SER D CA  1 
ATOM   482  C C   . SER A 1 77  ? 231.819 205.964 142.459 1.00 54.98  ? 77   SER D C   1 
ATOM   483  O O   . SER A 1 77  ? 230.945 205.207 142.016 1.00 54.98  ? 77   SER D O   1 
ATOM   484  C CB  . SER A 1 77  ? 231.551 208.453 142.281 1.00 54.98  ? 77   SER D CB  1 
ATOM   485  O OG  . SER A 1 77  ? 230.764 208.288 141.114 1.00 54.98  ? 77   SER D OG  1 
ATOM   486  N N   . THR A 1 78  ? 233.123 205.710 142.316 1.00 54.94  ? 78   THR D N   1 
ATOM   487  C CA  . THR A 1 78  ? 233.560 204.477 141.667 1.00 54.94  ? 78   THR D CA  1 
ATOM   488  C C   . THR A 1 78  ? 233.148 203.249 142.467 1.00 54.94  ? 78   THR D C   1 
ATOM   489  O O   . THR A 1 78  ? 232.926 202.178 141.891 1.00 54.94  ? 78   THR D O   1 
ATOM   490  C CB  . THR A 1 78  ? 235.075 204.491 141.461 1.00 54.94  ? 78   THR D CB  1 
ATOM   491  O OG1 . THR A 1 78  ? 235.729 204.746 142.711 1.00 54.94  ? 78   THR D OG1 1 
ATOM   492  C CG2 . THR A 1 78  ? 235.469 205.562 140.456 1.00 54.94  ? 78   THR D CG2 1 
ATOM   493  N N   . LEU A 1 79  ? 233.041 203.382 143.791 1.00 55.95  ? 79   LEU D N   1 
ATOM   494  C CA  . LEU A 1 79  ? 232.582 202.265 144.610 1.00 55.95  ? 79   LEU D CA  1 
ATOM   495  C C   . LEU A 1 79  ? 231.070 202.083 144.508 1.00 55.95  ? 79   LEU D C   1 
ATOM   496  O O   . LEU A 1 79  ? 230.581 200.949 144.460 1.00 55.95  ? 79   LEU D O   1 
ATOM   497  C CB  . LEU A 1 79  ? 233.003 202.480 146.065 1.00 55.95  ? 79   LEU D CB  1 
ATOM   498  C CG  . LEU A 1 79  ? 233.418 201.262 146.896 1.00 55.95  ? 79   LEU D CG  1 
ATOM   499  C CD1 . LEU A 1 79  ? 234.062 201.711 148.198 1.00 55.95  ? 79   LEU D CD1 1 
ATOM   500  C CD2 . LEU A 1 79  ? 232.239 200.343 147.179 1.00 55.95  ? 79   LEU D CD2 1 
ATOM   501  N N   . ALA A 1 80  ? 230.318 203.185 144.467 1.00 56.29  ? 80   ALA D N   1 
ATOM   502  C CA  . ALA A 1 80  ? 228.864 203.109 144.415 1.00 56.29  ? 80   ALA D CA  1 
ATOM   503  C C   . ALA A 1 80  ? 228.349 202.707 143.041 1.00 56.29  ? 80   ALA D C   1 
ATOM   504  O O   . ALA A 1 80  ? 227.208 202.244 142.936 1.00 56.29  ? 80   ALA D O   1 
ATOM   505  C CB  . ALA A 1 80  ? 228.252 204.450 144.822 1.00 56.29  ? 80   ALA D CB  1 
ATOM   506  N N   . GLN A 1 81  ? 229.152 202.879 141.988 1.00 59.04  ? 81   GLN D N   1 
ATOM   507  C CA  . GLN A 1 81  ? 228.723 202.452 140.660 1.00 59.04  ? 81   GLN D CA  1 
ATOM   508  C C   . GLN A 1 81  ? 228.488 200.950 140.563 1.00 59.04  ? 81   GLN D C   1 
ATOM   509  O O   . GLN A 1 81  ? 227.901 200.497 139.574 1.00 59.04  ? 81   GLN D O   1 
ATOM   510  C CB  . GLN A 1 81  ? 229.751 202.876 139.609 1.00 59.04  ? 81   GLN D CB  1 
ATOM   511  C CG  . GLN A 1 81  ? 229.683 204.345 139.230 1.00 59.04  ? 81   GLN D CG  1 
ATOM   512  C CD  . GLN A 1 81  ? 230.694 204.716 138.165 1.00 59.04  ? 81   GLN D CD  1 
ATOM   513  O OE1 . GLN A 1 81  ? 230.795 205.876 137.767 1.00 59.04  ? 81   GLN D OE1 1 
ATOM   514  N NE2 . GLN A 1 81  ? 231.449 203.730 137.696 1.00 59.04  ? 81   GLN D NE2 1 
ATOM   515  N N   . MET A 1 82  ? 228.923 200.171 141.552 1.00 61.06  ? 82   MET D N   1 
ATOM   516  C CA  . MET A 1 82  ? 228.725 198.728 141.558 1.00 61.06  ? 82   MET D CA  1 
ATOM   517  C C   . MET A 1 82  ? 227.393 198.314 142.173 1.00 61.06  ? 82   MET D C   1 
ATOM   518  O O   . MET A 1 82  ? 227.173 197.119 142.394 1.00 61.06  ? 82   MET D O   1 
ATOM   519  C CB  . MET A 1 82  ? 229.877 198.044 142.298 1.00 61.06  ? 82   MET D CB  1 
ATOM   520  C CG  . MET A 1 82  ? 231.220 198.168 141.595 1.00 61.06  ? 82   MET D CG  1 
ATOM   521  S SD  . MET A 1 82  ? 232.566 197.374 142.493 1.00 61.06  ? 82   MET D SD  1 
ATOM   522  C CE  . MET A 1 82  ? 232.618 198.375 143.976 1.00 61.06  ? 82   MET D CE  1 
ATOM   523  N N   . TYR A 1 83  ? 226.505 199.267 142.452 1.00 59.50  ? 83   TYR D N   1 
ATOM   524  C CA  . TYR A 1 83  ? 225.183 198.967 142.985 1.00 59.50  ? 83   TYR D CA  1 
ATOM   525  C C   . TYR A 1 83  ? 224.131 199.288 141.936 1.00 59.50  ? 83   TYR D C   1 
ATOM   526  O O   . TYR A 1 83  ? 224.024 200.450 141.514 1.00 59.50  ? 83   TYR D O   1 
ATOM   527  C CB  . TYR A 1 83  ? 224.917 199.760 144.264 1.00 59.50  ? 83   TYR D CB  1 
ATOM   528  C CG  . TYR A 1 83  ? 225.825 199.397 145.417 1.00 59.50  ? 83   TYR D CG  1 
ATOM   529  C CD1 . TYR A 1 83  ? 225.523 198.332 146.254 1.00 59.50  ? 83   TYR D CD1 1 
ATOM   530  C CD2 . TYR A 1 83  ? 226.980 200.124 145.672 1.00 59.50  ? 83   TYR D CD2 1 
ATOM   531  C CE1 . TYR A 1 83  ? 226.349 197.998 147.311 1.00 59.50  ? 83   TYR D CE1 1 
ATOM   532  C CE2 . TYR A 1 83  ? 227.811 199.798 146.726 1.00 59.50  ? 83   TYR D CE2 1 
ATOM   533  C CZ  . TYR A 1 83  ? 227.491 198.734 147.542 1.00 59.50  ? 83   TYR D CZ  1 
ATOM   534  O OH  . TYR A 1 83  ? 228.315 198.405 148.592 1.00 59.50  ? 83   TYR D OH  1 
ATOM   535  N N   . PRO A 1 84  ? 223.346 198.312 141.482 1.00 60.69  ? 84   PRO D N   1 
ATOM   536  C CA  . PRO A 1 84  ? 222.317 198.604 140.477 1.00 60.69  ? 84   PRO D CA  1 
ATOM   537  C C   . PRO A 1 84  ? 221.220 199.492 141.043 1.00 60.69  ? 84   PRO D C   1 
ATOM   538  O O   . PRO A 1 84  ? 220.846 199.383 142.213 1.00 60.69  ? 84   PRO D O   1 
ATOM   539  C CB  . PRO A 1 84  ? 221.777 197.217 140.105 1.00 60.69  ? 84   PRO D CB  1 
ATOM   540  C CG  . PRO A 1 84  ? 222.835 196.254 140.550 1.00 60.69  ? 84   PRO D CG  1 
ATOM   541  C CD  . PRO A 1 84  ? 223.448 196.872 141.766 1.00 60.69  ? 84   PRO D CD  1 
ATOM   542  N N   . LEU A 1 85  ? 220.703 200.378 140.193 1.00 61.82  ? 85   LEU D N   1 
ATOM   543  C CA  . LEU A 1 85  ? 219.638 201.293 140.580 1.00 61.82  ? 85   LEU D CA  1 
ATOM   544  C C   . LEU A 1 85  ? 218.245 200.721 140.357 1.00 61.82  ? 85   LEU D C   1 
ATOM   545  O O   . LEU A 1 85  ? 217.275 201.273 140.887 1.00 61.82  ? 85   LEU D O   1 
ATOM   546  C CB  . LEU A 1 85  ? 219.769 202.613 139.811 1.00 61.82  ? 85   LEU D CB  1 
ATOM   547  C CG  . LEU A 1 85  ? 221.004 203.463 140.110 1.00 61.82  ? 85   LEU D CG  1 
ATOM   548  C CD1 . LEU A 1 85  ? 221.000 204.728 139.266 1.00 61.82  ? 85   LEU D CD1 1 
ATOM   549  C CD2 . LEU A 1 85  ? 221.068 203.804 141.588 1.00 61.82  ? 85   LEU D CD2 1 
ATOM   550  N N   . GLN A 1 86  ? 218.120 199.636 139.592 1.00 67.99  ? 86   GLN D N   1 
ATOM   551  C CA  . GLN A 1 86  ? 216.812 199.058 139.313 1.00 67.99  ? 86   GLN D CA  1 
ATOM   552  C C   . GLN A 1 86  ? 216.339 198.115 140.410 1.00 67.99  ? 86   GLN D C   1 
ATOM   553  O O   . GLN A 1 86  ? 215.137 197.840 140.494 1.00 67.99  ? 86   GLN D O   1 
ATOM   554  C CB  . GLN A 1 86  ? 216.833 198.313 137.976 1.00 67.99  ? 86   GLN D CB  1 
ATOM   555  C CG  . GLN A 1 86  ? 217.075 199.196 136.759 1.00 67.99  ? 86   GLN D CG  1 
ATOM   556  C CD  . GLN A 1 86  ? 218.538 199.552 136.571 1.00 67.99  ? 86   GLN D CD  1 
ATOM   557  O OE1 . GLN A 1 86  ? 219.409 199.040 137.274 1.00 67.99  ? 86   GLN D OE1 1 
ATOM   558  N NE2 . GLN A 1 86  ? 218.814 200.433 135.617 1.00 67.99  ? 86   GLN D NE2 1 
ATOM   559  N N   . GLU A 1 87  ? 217.246 197.615 141.246 1.00 68.32  ? 87   GLU D N   1 
ATOM   560  C CA  . GLU A 1 87  ? 216.883 196.696 142.315 1.00 68.32  ? 87   GLU D CA  1 
ATOM   561  C C   . GLU A 1 87  ? 216.566 197.399 143.628 1.00 68.32  ? 87   GLU D C   1 
ATOM   562  O O   . GLU A 1 87  ? 216.065 196.751 144.553 1.00 68.32  ? 87   GLU D O   1 
ATOM   563  C CB  . GLU A 1 87  ? 218.006 195.678 142.539 1.00 68.32  ? 87   GLU D CB  1 
ATOM   564  C CG  . GLU A 1 87  ? 218.327 194.841 141.312 1.00 68.32  ? 87   GLU D CG  1 
ATOM   565  C CD  . GLU A 1 87  ? 219.350 193.760 141.594 1.00 68.32  ? 87   GLU D CD  1 
ATOM   566  O OE1 . GLU A 1 87  ? 219.696 193.562 142.777 1.00 68.32  ? 87   GLU D OE1 1 
ATOM   567  O OE2 . GLU A 1 87  ? 219.809 193.108 140.633 1.00 68.32  ? 87   GLU D OE2 1 
ATOM   568  N N   . ILE A 1 88  ? 216.841 198.695 143.733 1.00 63.47  ? 88   ILE D N   1 
ATOM   569  C CA  . ILE A 1 88  ? 216.526 199.448 144.941 1.00 63.47  ? 88   ILE D CA  1 
ATOM   570  C C   . ILE A 1 88  ? 215.069 199.884 144.886 1.00 63.47  ? 88   ILE D C   1 
ATOM   571  O O   . ILE A 1 88  ? 214.616 200.458 143.888 1.00 63.47  ? 88   ILE D O   1 
ATOM   572  C CB  . ILE A 1 88  ? 217.463 200.657 145.090 1.00 63.47  ? 88   ILE D CB  1 
ATOM   573  C CG1 . ILE A 1 88  ? 218.925 200.208 145.046 1.00 63.47  ? 88   ILE D CG1 1 
ATOM   574  C CG2 . ILE A 1 88  ? 217.173 201.400 146.384 1.00 63.47  ? 88   ILE D CG2 1 
ATOM   575  C CD1 . ILE A 1 88  ? 219.301 199.245 146.148 1.00 63.47  ? 88   ILE D CD1 1 
ATOM   576  N N   . GLN A 1 89  ? 214.327 199.612 145.960 1.00 66.99  ? 89   GLN D N   1 
ATOM   577  C CA  . GLN A 1 89  ? 212.919 199.972 146.039 1.00 66.99  ? 89   GLN D CA  1 
ATOM   578  C C   . GLN A 1 89  ? 212.645 201.147 146.966 1.00 66.99  ? 89   GLN D C   1 
ATOM   579  O O   . GLN A 1 89  ? 211.518 201.656 146.973 1.00 66.99  ? 89   GLN D O   1 
ATOM   580  C CB  . GLN A 1 89  ? 212.086 198.764 146.495 1.00 66.99  ? 89   GLN D CB  1 
ATOM   581  C CG  . GLN A 1 89  ? 212.206 197.549 145.588 1.00 66.99  ? 89   GLN D CG  1 
ATOM   582  C CD  . GLN A 1 89  ? 211.658 197.800 144.196 1.00 66.99  ? 89   GLN D CD  1 
ATOM   583  O OE1 . GLN A 1 89  ? 210.797 198.657 143.998 1.00 66.99  ? 89   GLN D OE1 1 
ATOM   584  N NE2 . GLN A 1 89  ? 212.158 197.050 143.221 1.00 66.99  ? 89   GLN D NE2 1 
ATOM   585  N N   . ASN A 1 90  ? 213.631 201.589 147.741 1.00 63.47  ? 90   ASN D N   1 
ATOM   586  C CA  . ASN A 1 90  ? 213.473 202.737 148.622 1.00 63.47  ? 90   ASN D CA  1 
ATOM   587  C C   . ASN A 1 90  ? 213.822 204.006 147.857 1.00 63.47  ? 90   ASN D C   1 
ATOM   588  O O   . ASN A 1 90  ? 214.861 204.071 147.192 1.00 63.47  ? 90   ASN D O   1 
ATOM   589  C CB  . ASN A 1 90  ? 214.360 202.589 149.860 1.00 63.47  ? 90   ASN D CB  1 
ATOM   590  C CG  . ASN A 1 90  ? 214.007 203.576 150.960 1.00 63.47  ? 90   ASN D CG  1 
ATOM   591  O OD1 . ASN A 1 90  ? 213.629 204.717 150.697 1.00 63.47  ? 90   ASN D OD1 1 
ATOM   592  N ND2 . ASN A 1 90  ? 214.132 203.135 152.206 1.00 63.47  ? 90   ASN D ND2 1 
ATOM   593  N N   . LEU A 1 91  ? 212.951 205.013 147.952 1.00 59.20  ? 91   LEU D N   1 
ATOM   594  C CA  . LEU A 1 91  ? 213.156 206.240 147.190 1.00 59.20  ? 91   LEU D CA  1 
ATOM   595  C C   . LEU A 1 91  ? 214.339 207.039 147.723 1.00 59.20  ? 91   LEU D C   1 
ATOM   596  O O   . LEU A 1 91  ? 215.099 207.624 146.944 1.00 59.20  ? 91   LEU D O   1 
ATOM   597  C CB  . LEU A 1 91  ? 211.885 207.091 147.203 1.00 59.20  ? 91   LEU D CB  1 
ATOM   598  C CG  . LEU A 1 91  ? 210.754 206.692 146.249 1.00 59.20  ? 91   LEU D CG  1 
ATOM   599  C CD1 . LEU A 1 91  ? 211.293 206.457 144.845 1.00 59.20  ? 91   LEU D CD1 1 
ATOM   600  C CD2 . LEU A 1 91  ? 209.988 205.474 146.752 1.00 59.20  ? 91   LEU D CD2 1 
ATOM   601  N N   . THR A 1 92  ? 214.511 207.075 149.046 1.00 55.99  ? 92   THR D N   1 
ATOM   602  C CA  . THR A 1 92  ? 215.611 207.836 149.632 1.00 55.99  ? 92   THR D CA  1 
ATOM   603  C C   . THR A 1 92  ? 216.960 207.249 149.232 1.00 55.99  ? 92   THR D C   1 
ATOM   604  O O   . THR A 1 92  ? 217.865 207.973 148.796 1.00 55.99  ? 92   THR D O   1 
ATOM   605  C CB  . THR A 1 92  ? 215.467 207.870 151.155 1.00 55.99  ? 92   THR D CB  1 
ATOM   606  O OG1 . THR A 1 92  ? 214.265 208.567 151.508 1.00 55.99  ? 92   THR D OG1 1 
ATOM   607  C CG2 . THR A 1 92  ? 216.657 208.567 151.791 1.00 55.99  ? 92   THR D CG2 1 
ATOM   608  N N   . VAL A 1 93  ? 217.112 205.931 149.380 1.00 55.90  ? 93   VAL D N   1 
ATOM   609  C CA  . VAL A 1 93  ? 218.363 205.275 149.012 1.00 55.90  ? 93   VAL D CA  1 
ATOM   610  C C   . VAL A 1 93  ? 218.618 205.416 147.517 1.00 55.90  ? 93   VAL D C   1 
ATOM   611  O O   . VAL A 1 93  ? 219.758 205.626 147.083 1.00 55.90  ? 93   VAL D O   1 
ATOM   612  C CB  . VAL A 1 93  ? 218.337 203.798 149.447 1.00 55.90  ? 93   VAL D CB  1 
ATOM   613  C CG1 . VAL A 1 93  ? 219.635 203.103 149.066 1.00 55.90  ? 93   VAL D CG1 1 
ATOM   614  C CG2 . VAL A 1 93  ? 218.088 203.692 150.943 1.00 55.90  ? 93   VAL D CG2 1 
ATOM   615  N N   . LYS A 1 94  ? 217.561 205.312 146.707 1.00 54.94  ? 94   LYS D N   1 
ATOM   616  C CA  . LYS A 1 94  ? 217.721 205.455 145.264 1.00 54.94  ? 94   LYS D CA  1 
ATOM   617  C C   . LYS A 1 94  ? 218.186 206.858 144.897 1.00 54.94  ? 94   LYS D C   1 
ATOM   618  O O   . LYS A 1 94  ? 219.071 207.022 144.050 1.00 54.94  ? 94   LYS D O   1 
ATOM   619  C CB  . LYS A 1 94  ? 216.410 205.121 144.552 1.00 54.94  ? 94   LYS D CB  1 
ATOM   620  C CG  . LYS A 1 94  ? 216.486 205.224 143.038 1.00 54.94  ? 94   LYS D CG  1 
ATOM   621  C CD  . LYS A 1 94  ? 215.135 204.961 142.394 1.00 54.94  ? 94   LYS D CD  1 
ATOM   622  C CE  . LYS A 1 94  ? 214.628 203.568 142.723 1.00 54.94  ? 94   LYS D CE  1 
ATOM   623  N NZ  . LYS A 1 94  ? 213.304 203.299 142.098 1.00 54.94  ? 94   LYS D NZ  1 
ATOM   624  N N   . LEU A 1 95  ? 217.607 207.882 145.528 1.00 53.63  ? 95   LEU D N   1 
ATOM   625  C CA  . LEU A 1 95  ? 218.026 209.252 145.251 1.00 53.63  ? 95   LEU D CA  1 
ATOM   626  C C   . LEU A 1 95  ? 219.464 209.492 145.694 1.00 53.63  ? 95   LEU D C   1 
ATOM   627  O O   . LEU A 1 95  ? 220.234 210.150 144.986 1.00 53.63  ? 95   LEU D O   1 
ATOM   628  C CB  . LEU A 1 95  ? 217.082 210.243 145.931 1.00 53.63  ? 95   LEU D CB  1 
ATOM   629  C CG  . LEU A 1 95  ? 215.681 210.375 145.331 1.00 53.63  ? 95   LEU D CG  1 
ATOM   630  C CD1 . LEU A 1 95  ? 214.867 211.410 146.089 1.00 53.63  ? 95   LEU D CD1 1 
ATOM   631  C CD2 . LEU A 1 95  ? 215.761 210.728 143.855 1.00 53.63  ? 95   LEU D CD2 1 
ATOM   632  N N   . GLN A 1 96  ? 219.846 208.963 146.860 1.00 53.40  ? 96   GLN D N   1 
ATOM   633  C CA  . GLN A 1 96  ? 221.222 209.129 147.319 1.00 53.40  ? 96   GLN D CA  1 
ATOM   634  C C   . GLN A 1 96  ? 222.205 208.447 146.374 1.00 53.40  ? 96   GLN D C   1 
ATOM   635  O O   . GLN A 1 96  ? 223.252 209.015 146.038 1.00 53.40  ? 96   GLN D O   1 
ATOM   636  C CB  . GLN A 1 96  ? 221.378 208.588 148.740 1.00 53.40  ? 96   GLN D CB  1 
ATOM   637  C CG  . GLN A 1 96  ? 220.598 209.361 149.791 1.00 53.40  ? 96   GLN D CG  1 
ATOM   638  C CD  . GLN A 1 96  ? 220.970 208.959 151.204 1.00 53.40  ? 96   GLN D CD  1 
ATOM   639  O OE1 . GLN A 1 96  ? 222.129 208.664 151.493 1.00 53.40  ? 96   GLN D OE1 1 
ATOM   640  N NE2 . GLN A 1 96  ? 219.985 208.944 152.094 1.00 53.40  ? 96   GLN D NE2 1 
ATOM   641  N N   . LEU A 1 97  ? 221.881 207.231 145.925 1.00 56.17  ? 97   LEU D N   1 
ATOM   642  C CA  . LEU A 1 97  ? 222.757 206.532 144.990 1.00 56.17  ? 97   LEU D CA  1 
ATOM   643  C C   . LEU A 1 97  ? 222.838 207.260 143.654 1.00 56.17  ? 97   LEU D C   1 
ATOM   644  O O   . LEU A 1 97  ? 223.917 207.352 143.058 1.00 56.17  ? 97   LEU D O   1 
ATOM   645  C CB  . LEU A 1 97  ? 222.274 205.096 144.790 1.00 56.17  ? 97   LEU D CB  1 
ATOM   646  C CG  . LEU A 1 97  ? 222.544 204.120 145.935 1.00 56.17  ? 97   LEU D CG  1 
ATOM   647  C CD1 . LEU A 1 97  ? 221.916 202.767 145.643 1.00 56.17  ? 97   LEU D CD1 1 
ATOM   648  C CD2 . LEU A 1 97  ? 224.039 203.979 146.165 1.00 56.17  ? 97   LEU D CD2 1 
ATOM   649  N N   . GLN A 1 98  ? 221.711 207.784 143.169 1.00 55.16  ? 98   GLN D N   1 
ATOM   650  C CA  . GLN A 1 98  ? 221.717 208.512 141.904 1.00 55.16  ? 98   GLN D CA  1 
ATOM   651  C C   . GLN A 1 98  ? 222.541 209.788 142.008 1.00 55.16  ? 98   GLN D C   1 
ATOM   652  O O   . GLN A 1 98  ? 223.243 210.159 141.061 1.00 55.16  ? 98   GLN D O   1 
ATOM   653  C CB  . GLN A 1 98  ? 220.284 208.826 141.476 1.00 55.16  ? 98   GLN D CB  1 
ATOM   654  C CG  . GLN A 1 98  ? 220.172 209.547 140.145 1.00 55.16  ? 98   GLN D CG  1 
ATOM   655  C CD  . GLN A 1 98  ? 218.738 209.878 139.784 1.00 55.16  ? 98   GLN D CD  1 
ATOM   656  O OE1 . GLN A 1 98  ? 217.814 209.599 140.547 1.00 55.16  ? 98   GLN D OE1 1 
ATOM   657  N NE2 . GLN A 1 98  ? 218.545 210.477 138.615 1.00 55.16  ? 98   GLN D NE2 1 
ATOM   658  N N   . ALA A 1 99  ? 222.472 210.472 143.153 1.00 54.97  ? 99   ALA D N   1 
ATOM   659  C CA  . ALA A 1 99  ? 223.276 211.674 143.338 1.00 54.97  ? 99   ALA D CA  1 
ATOM   660  C C   . ALA A 1 99  ? 224.747 211.340 143.539 1.00 54.97  ? 99   ALA D C   1 
ATOM   661  O O   . ALA A 1 99  ? 225.615 212.170 143.246 1.00 54.97  ? 99   ALA D O   1 
ATOM   662  C CB  . ALA A 1 99  ? 222.748 212.484 144.522 1.00 54.97  ? 99   ALA D CB  1 
ATOM   663  N N   . LEU A 1 100 ? 225.049 210.138 144.031 1.00 54.69  ? 100  LEU D N   1 
ATOM   664  C CA  . LEU A 1 100 ? 226.433 209.743 144.261 1.00 54.69  ? 100  LEU D CA  1 
ATOM   665  C C   . LEU A 1 100 ? 227.092 209.144 143.026 1.00 54.69  ? 100  LEU D C   1 
ATOM   666  O O   . LEU A 1 100 ? 228.308 209.288 142.853 1.00 54.69  ? 100  LEU D O   1 
ATOM   667  C CB  . LEU A 1 100 ? 226.506 208.746 145.421 1.00 54.69  ? 100  LEU D CB  1 
ATOM   668  C CG  . LEU A 1 100 ? 227.900 208.394 145.940 1.00 54.69  ? 100  LEU D CG  1 
ATOM   669  C CD1 . LEU A 1 100 ? 228.659 209.654 146.324 1.00 54.69  ? 100  LEU D CD1 1 
ATOM   670  C CD2 . LEU A 1 100 ? 227.800 207.448 147.123 1.00 54.69  ? 100  LEU D CD2 1 
ATOM   671  N N   . GLN A 1 101 ? 226.323 208.482 142.161 1.00 58.21  ? 101  GLN D N   1 
ATOM   672  C CA  . GLN A 1 101 ? 226.857 207.855 140.958 1.00 58.21  ? 101  GLN D CA  1 
ATOM   673  C C   . GLN A 1 101 ? 227.014 208.827 139.793 1.00 58.21  ? 101  GLN D C   1 
ATOM   674  O O   . GLN A 1 101 ? 227.173 208.380 138.651 1.00 58.21  ? 101  GLN D O   1 
ATOM   675  C CB  . GLN A 1 101 ? 225.968 206.683 140.535 1.00 58.21  ? 101  GLN D CB  1 
ATOM   676  C CG  . GLN A 1 101 ? 225.978 205.508 141.497 1.00 58.21  ? 101  GLN D CG  1 
ATOM   677  C CD  . GLN A 1 101 ? 225.061 204.387 141.052 1.00 58.21  ? 101  GLN D CD  1 
ATOM   678  O OE1 . GLN A 1 101 ? 224.811 203.440 141.798 1.00 58.21  ? 101  GLN D OE1 1 
ATOM   679  N NE2 . GLN A 1 101 ? 224.554 204.488 139.829 1.00 58.21  ? 101  GLN D NE2 1 
ATOM   680  N N   . GLN A 1 102 ? 226.978 210.134 140.043 1.00 60.88  ? 102  GLN D N   1 
ATOM   681  C CA  . GLN A 1 102 ? 227.098 211.132 138.981 1.00 60.88  ? 102  GLN D CA  1 
ATOM   682  C C   . GLN A 1 102 ? 228.558 211.216 138.554 1.00 60.88  ? 102  GLN D C   1 
ATOM   683  O O   . GLN A 1 102 ? 229.347 211.992 139.095 1.00 60.88  ? 102  GLN D O   1 
ATOM   684  C CB  . GLN A 1 102 ? 226.575 212.484 139.448 1.00 60.88  ? 102  GLN D CB  1 
ATOM   685  C CG  . GLN A 1 102 ? 225.095 212.496 139.795 1.00 60.88  ? 102  GLN D CG  1 
ATOM   686  C CD  . GLN A 1 102 ? 224.207 212.253 138.589 1.00 60.88  ? 102  GLN D CD  1 
ATOM   687  O OE1 . GLN A 1 102 ? 224.612 212.477 137.448 1.00 60.88  ? 102  GLN D OE1 1 
ATOM   688  N NE2 . GLN A 1 102 ? 222.988 211.791 138.838 1.00 60.88  ? 102  GLN D NE2 1 
ATOM   689  N N   . ASN A 1 103 ? 228.921 210.402 137.565 1.00 64.50  ? 103  ASN D N   1 
ATOM   690  C CA  . ASN A 1 103 ? 230.279 210.395 137.024 1.00 64.50  ? 103  ASN D CA  1 
ATOM   691  C C   . ASN A 1 103 ? 230.329 211.258 135.762 1.00 64.50  ? 103  ASN D C   1 
ATOM   692  O O   . ASN A 1 103 ? 230.463 210.780 134.636 1.00 64.50  ? 103  ASN D O   1 
ATOM   693  C CB  . ASN A 1 103 ? 230.735 208.963 136.757 1.00 64.50  ? 103  ASN D CB  1 
ATOM   694  C CG  . ASN A 1 103 ? 229.753 208.185 135.902 1.00 64.50  ? 103  ASN D CG  1 
ATOM   695  O OD1 . ASN A 1 103 ? 228.610 208.602 135.714 1.00 64.50  ? 103  ASN D OD1 1 
ATOM   696  N ND2 . ASN A 1 103 ? 230.196 207.045 135.382 1.00 64.50  ? 103  ASN D ND2 1 
ATOM   697  N N   . GLY A 1 104 ? 230.221 212.565 135.982 1.00 66.66  ? 104  GLY D N   1 
ATOM   698  C CA  . GLY A 1 104 ? 230.175 213.514 134.888 1.00 66.66  ? 104  GLY D CA  1 
ATOM   699  C C   . GLY A 1 104 ? 231.489 213.695 134.156 1.00 66.66  ? 104  GLY D C   1 
ATOM   700  O O   . GLY A 1 104 ? 231.591 213.383 132.966 1.00 66.66  ? 104  GLY D O   1 
ATOM   701  N N   . SER A 1 105 ? 232.505 214.196 134.857 1.00 70.74  ? 105  SER D N   1 
ATOM   702  C CA  . SER A 1 105 ? 233.787 214.527 134.252 1.00 70.74  ? 105  SER D CA  1 
ATOM   703  C C   . SER A 1 105 ? 234.757 213.350 134.229 1.00 70.74  ? 105  SER D C   1 
ATOM   704  O O   . SER A 1 105 ? 235.972 213.563 134.138 1.00 70.74  ? 105  SER D O   1 
ATOM   705  C CB  . SER A 1 105 ? 234.421 215.713 134.983 1.00 70.74  ? 105  SER D CB  1 
ATOM   706  O OG  . SER A 1 105 ? 234.630 215.416 136.352 1.00 70.74  ? 105  SER D OG  1 
ATOM   707  N N   . SER A 1 106 ? 234.255 212.118 134.308 1.00 68.85  ? 106  SER D N   1 
ATOM   708  C CA  . SER A 1 106 ? 235.105 210.938 134.288 1.00 68.85  ? 106  SER D CA  1 
ATOM   709  C C   . SER A 1 106 ? 234.760 209.948 133.187 1.00 68.85  ? 106  SER D C   1 
ATOM   710  O O   . SER A 1 106 ? 235.518 208.993 132.983 1.00 68.85  ? 106  SER D O   1 
ATOM   711  C CB  . SER A 1 106 ? 235.051 210.215 135.643 1.00 68.85  ? 106  SER D CB  1 
ATOM   712  O OG  . SER A 1 106 ? 233.733 209.793 135.943 1.00 68.85  ? 106  SER D OG  1 
ATOM   713  N N   . VAL A 1 107 ? 233.649 210.139 132.474 1.00 68.39  ? 107  VAL D N   1 
ATOM   714  C CA  . VAL A 1 107 ? 233.287 209.204 131.414 1.00 68.39  ? 107  VAL D CA  1 
ATOM   715  C C   . VAL A 1 107 ? 234.118 209.441 130.159 1.00 68.39  ? 107  VAL D C   1 
ATOM   716  O O   . VAL A 1 107 ? 234.360 208.506 129.387 1.00 68.39  ? 107  VAL D O   1 
ATOM   717  C CB  . VAL A 1 107 ? 231.782 209.297 131.111 1.00 68.39  ? 107  VAL D CB  1 
ATOM   718  C CG1 . VAL A 1 107 ? 230.978 208.661 132.232 1.00 68.39  ? 107  VAL D CG1 1 
ATOM   719  C CG2 . VAL A 1 107 ? 231.373 210.747 130.916 1.00 68.39  ? 107  VAL D CG2 1 
ATOM   720  N N   . LEU A 1 108 ? 234.565 210.672 129.929 1.00 67.86  ? 108  LEU D N   1 
ATOM   721  C CA  . LEU A 1 108 ? 235.368 210.973 128.756 1.00 67.86  ? 108  LEU D CA  1 
ATOM   722  C C   . LEU A 1 108 ? 236.790 210.445 128.930 1.00 67.86  ? 108  LEU D C   1 
ATOM   723  O O   . LEU A 1 108 ? 237.203 210.026 130.015 1.00 67.86  ? 108  LEU D O   1 
ATOM   724  C CB  . LEU A 1 108 ? 235.392 212.478 128.491 1.00 67.86  ? 108  LEU D CB  1 
ATOM   725  C CG  . LEU A 1 108 ? 234.073 213.129 128.072 1.00 67.86  ? 108  LEU D CG  1 
ATOM   726  C CD1 . LEU A 1 108 ? 234.277 214.610 127.800 1.00 67.86  ? 108  LEU D CD1 1 
ATOM   727  C CD2 . LEU A 1 108 ? 233.497 212.430 126.851 1.00 67.86  ? 108  LEU D CD2 1 
ATOM   728  N N   . SER A 1 109 ? 237.544 210.469 127.834 1.00 71.31  ? 109  SER D N   1 
ATOM   729  C CA  . SER A 1 109 ? 238.933 210.046 127.874 1.00 71.31  ? 109  SER D CA  1 
ATOM   730  C C   . SER A 1 109 ? 239.770 211.040 128.675 1.00 71.31  ? 109  SER D C   1 
ATOM   731  O O   . SER A 1 109 ? 239.348 212.165 128.960 1.00 71.31  ? 109  SER D O   1 
ATOM   732  C CB  . SER A 1 109 ? 239.493 209.908 126.458 1.00 71.31  ? 109  SER D CB  1 
ATOM   733  O OG  . SER A 1 109 ? 240.855 209.517 126.485 1.00 71.31  ? 109  SER D OG  1 
ATOM   734  N N   . GLU A 1 110 ? 240.977 210.605 129.043 1.00 75.18  ? 110  GLU D N   1 
ATOM   735  C CA  . GLU A 1 110 ? 241.861 211.464 129.824 1.00 75.18  ? 110  GLU D CA  1 
ATOM   736  C C   . GLU A 1 110 ? 242.287 212.690 129.026 1.00 75.18  ? 110  GLU D C   1 
ATOM   737  O O   . GLU A 1 110 ? 242.294 213.809 129.553 1.00 75.18  ? 110  GLU D O   1 
ATOM   738  C CB  . GLU A 1 110 ? 243.083 210.672 130.289 1.00 75.18  ? 110  GLU D CB  1 
ATOM   739  C CG  . GLU A 1 110 ? 243.972 211.418 131.271 1.00 75.18  ? 110  GLU D CG  1 
ATOM   740  C CD  . GLU A 1 110 ? 243.313 211.616 132.623 1.00 75.18  ? 110  GLU D CD  1 
ATOM   741  O OE1 . GLU A 1 110 ? 242.374 210.859 132.948 1.00 75.18  ? 110  GLU D OE1 1 
ATOM   742  O OE2 . GLU A 1 110 ? 243.735 212.529 133.362 1.00 75.18  ? 110  GLU D OE2 1 
ATOM   743  N N   . ASP A 1 111 ? 242.638 212.500 127.752 1.00 77.18  ? 111  ASP D N   1 
ATOM   744  C CA  . ASP A 1 111 ? 243.026 213.630 126.915 1.00 77.18  ? 111  ASP D CA  1 
ATOM   745  C C   . ASP A 1 111 ? 241.858 214.583 126.695 1.00 77.18  ? 111  ASP D C   1 
ATOM   746  O O   . ASP A 1 111 ? 242.026 215.806 126.763 1.00 77.18  ? 111  ASP D O   1 
ATOM   747  C CB  . ASP A 1 111 ? 243.571 213.130 125.578 1.00 77.18  ? 111  ASP D CB  1 
ATOM   748  C CG  . ASP A 1 111 ? 243.983 214.261 124.657 1.00 77.18  ? 111  ASP D CG  1 
ATOM   749  O OD1 . ASP A 1 111 ? 244.997 214.929 124.950 1.00 77.18  ? 111  ASP D OD1 1 
ATOM   750  O OD2 . ASP A 1 111 ? 243.292 214.483 123.640 1.00 77.18  ? 111  ASP D OD2 1 
ATOM   751  N N   . LYS A 1 112 ? 240.665 214.041 126.437 1.00 71.53  ? 112  LYS D N   1 
ATOM   752  C CA  . LYS A 1 112 ? 239.494 214.891 126.244 1.00 71.53  ? 112  LYS D CA  1 
ATOM   753  C C   . LYS A 1 112 ? 239.147 215.651 127.518 1.00 71.53  ? 112  LYS D C   1 
ATOM   754  O O   . LYS A 1 112 ? 238.793 216.835 127.466 1.00 71.53  ? 112  LYS D O   1 
ATOM   755  C CB  . LYS A 1 112 ? 238.305 214.049 125.781 1.00 71.53  ? 112  LYS D CB  1 
ATOM   756  C CG  . LYS A 1 112 ? 238.485 213.416 124.412 1.00 71.53  ? 112  LYS D CG  1 
ATOM   757  C CD  . LYS A 1 112 ? 238.642 214.474 123.334 1.00 71.53  ? 112  LYS D CD  1 
ATOM   758  C CE  . LYS A 1 112 ? 238.750 213.845 121.955 1.00 71.53  ? 112  LYS D CE  1 
ATOM   759  N NZ  . LYS A 1 112 ? 237.538 213.050 121.614 1.00 71.53  ? 112  LYS D NZ  1 
ATOM   760  N N   . SER A 1 113 ? 239.245 214.988 128.673 1.00 70.25  ? 113  SER D N   1 
ATOM   761  C CA  . SER A 1 113 ? 238.960 215.662 129.935 1.00 70.25  ? 113  SER D CA  1 
ATOM   762  C C   . SER A 1 113 ? 239.972 216.766 130.213 1.00 70.25  ? 113  SER D C   1 
ATOM   763  O O   . SER A 1 113 ? 239.600 217.860 130.655 1.00 70.25  ? 113  SER D O   1 
ATOM   764  C CB  . SER A 1 113 ? 238.941 214.649 131.080 1.00 70.25  ? 113  SER D CB  1 
ATOM   765  O OG  . SER A 1 113 ? 237.929 213.677 130.883 1.00 70.25  ? 113  SER D OG  1 
ATOM   766  N N   . LYS A 1 114 ? 241.257 216.499 129.961 1.00 70.64  ? 114  LYS D N   1 
ATOM   767  C CA  . LYS A 1 114 ? 242.272 217.531 130.144 1.00 70.64  ? 114  LYS D CA  1 
ATOM   768  C C   . LYS A 1 114 ? 242.042 218.703 129.199 1.00 70.64  ? 114  LYS D C   1 
ATOM   769  O O   . LYS A 1 114 ? 242.205 219.865 129.590 1.00 70.64  ? 114  LYS D O   1 
ATOM   770  C CB  . LYS A 1 114 ? 243.668 216.943 129.940 1.00 70.64  ? 114  LYS D CB  1 
ATOM   771  C CG  . LYS A 1 114 ? 244.199 216.172 131.136 1.00 70.64  ? 114  LYS D CG  1 
ATOM   772  C CD  . LYS A 1 114 ? 245.624 215.701 130.895 1.00 70.64  ? 114  LYS D CD  1 
ATOM   773  C CE  . LYS A 1 114 ? 246.251 215.157 132.168 1.00 70.64  ? 114  LYS D CE  1 
ATOM   774  N NZ  . LYS A 1 114 ? 245.467 214.029 132.740 1.00 70.64  ? 114  LYS D NZ  1 
ATOM   775  N N   . ARG A 1 115 ? 241.649 218.420 127.955 1.00 68.39  ? 115  ARG D N   1 
ATOM   776  C CA  . ARG A 1 115 ? 241.375 219.495 127.007 1.00 68.39  ? 115  ARG D CA  1 
ATOM   777  C C   . ARG A 1 115 ? 240.181 220.328 127.453 1.00 68.39  ? 115  ARG D C   1 
ATOM   778  O O   . ARG A 1 115 ? 240.202 221.560 127.351 1.00 68.39  ? 115  ARG D O   1 
ATOM   779  C CB  . ARG A 1 115 ? 241.135 218.918 125.612 1.00 68.39  ? 115  ARG D CB  1 
ATOM   780  C CG  . ARG A 1 115 ? 241.076 219.967 124.516 1.00 68.39  ? 115  ARG D CG  1 
ATOM   781  C CD  . ARG A 1 115 ? 242.437 220.605 124.298 1.00 68.39  ? 115  ARG D CD  1 
ATOM   782  N NE  . ARG A 1 115 ? 242.376 221.725 123.364 1.00 68.39  ? 115  ARG D NE  1 
ATOM   783  C CZ  . ARG A 1 115 ? 242.315 223.000 123.732 1.00 68.39  ? 115  ARG D CZ  1 
ATOM   784  N NH1 . ARG A 1 115 ? 242.261 223.956 122.814 1.00 68.39  ? 115  ARG D NH1 1 
ATOM   785  N NH2 . ARG A 1 115 ? 242.314 223.321 125.018 1.00 68.39  ? 115  ARG D NH2 1 
ATOM   786  N N   . LEU A 1 116 ? 239.132 219.674 127.957 1.00 64.96  ? 116  LEU D N   1 
ATOM   787  C CA  . LEU A 1 116 ? 237.964 220.409 128.433 1.00 64.96  ? 116  LEU D CA  1 
ATOM   788  C C   . LEU A 1 116 ? 238.306 221.267 129.645 1.00 64.96  ? 116  LEU D C   1 
ATOM   789  O O   . LEU A 1 116 ? 237.850 222.413 129.750 1.00 64.96  ? 116  LEU D O   1 
ATOM   790  C CB  . LEU A 1 116 ? 236.832 219.438 128.764 1.00 64.96  ? 116  LEU D CB  1 
ATOM   791  C CG  . LEU A 1 116 ? 235.530 220.075 129.254 1.00 64.96  ? 116  LEU D CG  1 
ATOM   792  C CD1 . LEU A 1 116 ? 234.975 221.028 128.208 1.00 64.96  ? 116  LEU D CD1 1 
ATOM   793  C CD2 . LEU A 1 116 ? 234.510 219.007 129.604 1.00 64.96  ? 116  LEU D CD2 1 
ATOM   794  N N   . ASN A 1 117 ? 239.109 220.734 130.569 1.00 65.42  ? 117  ASN D N   1 
ATOM   795  C CA  . ASN A 1 117 ? 239.521 221.522 131.726 1.00 65.42  ? 117  ASN D CA  1 
ATOM   796  C C   . ASN A 1 117 ? 240.376 222.711 131.304 1.00 65.42  ? 117  ASN D C   1 
ATOM   797  O O   . ASN A 1 117 ? 240.227 223.815 131.843 1.00 65.42  ? 117  ASN D O   1 
ATOM   798  C CB  . ASN A 1 117 ? 240.275 220.643 132.724 1.00 65.42  ? 117  ASN D CB  1 
ATOM   799  C CG  . ASN A 1 117 ? 239.388 219.591 133.359 1.00 65.42  ? 117  ASN D CG  1 
ATOM   800  O OD1 . ASN A 1 117 ? 239.743 218.414 133.415 1.00 65.42  ? 117  ASN D OD1 1 
ATOM   801  N ND2 . ASN A 1 117 ? 238.225 220.011 133.841 1.00 65.42  ? 117  ASN D ND2 1 
ATOM   802  N N   . THR A 1 118 ? 241.273 222.506 130.336 1.00 65.76  ? 118  THR D N   1 
ATOM   803  C CA  . THR A 1 118 ? 242.086 223.609 129.834 1.00 65.76  ? 118  THR D CA  1 
ATOM   804  C C   . THR A 1 118 ? 241.218 224.674 129.175 1.00 65.76  ? 118  THR D C   1 
ATOM   805  O O   . THR A 1 118 ? 241.454 225.875 129.355 1.00 65.76  ? 118  THR D O   1 
ATOM   806  C CB  . THR A 1 118 ? 243.132 223.084 128.849 1.00 65.76  ? 118  THR D CB  1 
ATOM   807  O OG1 . THR A 1 118 ? 243.928 222.078 129.487 1.00 65.76  ? 118  THR D OG1 1 
ATOM   808  C CG2 . THR A 1 118 ? 244.037 224.212 128.377 1.00 65.76  ? 118  THR D CG2 1 
ATOM   809  N N   . ILE A 1 119 ? 240.207 224.253 128.411 1.00 64.16  ? 119  ILE D N   1 
ATOM   810  C CA  . ILE A 1 119 ? 239.301 225.207 127.777 1.00 64.16  ? 119  ILE D CA  1 
ATOM   811  C C   . ILE A 1 119 ? 238.542 226.003 128.830 1.00 64.16  ? 119  ILE D C   1 
ATOM   812  O O   . ILE A 1 119 ? 238.411 227.230 128.728 1.00 64.16  ? 119  ILE D O   1 
ATOM   813  C CB  . ILE A 1 119 ? 238.341 224.477 126.818 1.00 64.16  ? 119  ILE D CB  1 
ATOM   814  C CG1 . ILE A 1 119 ? 239.100 223.956 125.598 1.00 64.16  ? 119  ILE D CG1 1 
ATOM   815  C CG2 . ILE A 1 119 ? 237.210 225.396 126.386 1.00 64.16  ? 119  ILE D CG2 1 
ATOM   816  C CD1 . ILE A 1 119 ? 238.244 223.150 124.651 1.00 64.16  ? 119  ILE D CD1 1 
ATOM   817  N N   . LEU A 1 120 ? 238.032 225.322 129.858 1.00 62.95  ? 120  LEU D N   1 
ATOM   818  C CA  . LEU A 1 120 ? 237.315 226.017 130.924 1.00 62.95  ? 120  LEU D CA  1 
ATOM   819  C C   . LEU A 1 120 ? 238.218 227.026 131.622 1.00 62.95  ? 120  LEU D C   1 
ATOM   820  O O   . LEU A 1 120 ? 237.818 228.172 131.866 1.00 62.95  ? 120  LEU D O   1 
ATOM   821  C CB  . LEU A 1 120 ? 236.757 225.007 131.927 1.00 62.95  ? 120  LEU D CB  1 
ATOM   822  C CG  . LEU A 1 120 ? 235.625 224.105 131.435 1.00 62.95  ? 120  LEU D CG  1 
ATOM   823  C CD1 . LEU A 1 120 ? 235.188 223.147 132.531 1.00 62.95  ? 120  LEU D CD1 1 
ATOM   824  C CD2 . LEU A 1 120 ? 234.452 224.940 130.951 1.00 62.95  ? 120  LEU D CD2 1 
ATOM   825  N N   . ASN A 1 121 ? 239.451 226.621 131.939 1.00 63.19  ? 121  ASN D N   1 
ATOM   826  C CA  . ASN A 1 121 ? 240.368 227.519 132.633 1.00 63.19  ? 121  ASN D CA  1 
ATOM   827  C C   . ASN A 1 121 ? 240.728 228.723 131.773 1.00 63.19  ? 121  ASN D C   1 
ATOM   828  O O   . ASN A 1 121 ? 240.750 229.859 132.263 1.00 63.19  ? 121  ASN D O   1 
ATOM   829  C CB  . ASN A 1 121 ? 241.628 226.763 133.055 1.00 63.19  ? 121  ASN D CB  1 
ATOM   830  C CG  . ASN A 1 121 ? 241.378 225.812 134.208 1.00 63.19  ? 121  ASN D CG  1 
ATOM   831  O OD1 . ASN A 1 121 ? 241.698 224.626 134.131 1.00 63.19  ? 121  ASN D OD1 1 
ATOM   832  N ND2 . ASN A 1 121 ? 240.803 226.330 135.287 1.00 63.19  ? 121  ASN D ND2 1 
ATOM   833  N N   . THR A 1 122 ? 241.005 228.503 130.484 1.00 63.04  ? 122  THR D N   1 
ATOM   834  C CA  . THR A 1 122 ? 241.393 229.625 129.638 1.00 63.04  ? 122  THR D CA  1 
ATOM   835  C C   . THR A 1 122 ? 240.218 230.561 129.377 1.00 63.04  ? 122  THR D C   1 
ATOM   836  O O   . THR A 1 122 ? 240.413 231.777 129.291 1.00 63.04  ? 122  THR D O   1 
ATOM   837  C CB  . THR A 1 122 ? 242.009 229.132 128.322 1.00 63.04  ? 122  THR D CB  1 
ATOM   838  O OG1 . THR A 1 122 ? 242.561 230.245 127.607 1.00 63.04  ? 122  THR D OG1 1 
ATOM   839  C CG2 . THR A 1 122 ? 240.980 228.446 127.443 1.00 63.04  ? 122  THR D CG2 1 
ATOM   840  N N   . MET A 1 123 ? 238.992 230.033 129.297 1.00 61.39  ? 123  MET D N   1 
ATOM   841  C CA  . MET A 1 123 ? 237.835 230.912 129.158 1.00 61.39  ? 123  MET D CA  1 
ATOM   842  C C   . MET A 1 123 ? 237.605 231.719 130.429 1.00 61.39  ? 123  MET D C   1 
ATOM   843  O O   . MET A 1 123 ? 237.288 232.914 130.364 1.00 61.39  ? 123  MET D O   1 
ATOM   844  C CB  . MET A 1 123 ? 236.589 230.101 128.802 1.00 61.39  ? 123  MET D CB  1 
ATOM   845  C CG  . MET A 1 123 ? 236.607 229.515 127.400 1.00 61.39  ? 123  MET D CG  1 
ATOM   846  S SD  . MET A 1 123 ? 235.045 228.730 126.959 1.00 61.39  ? 123  MET D SD  1 
ATOM   847  C CE  . MET A 1 123 ? 234.860 227.565 128.306 1.00 61.39  ? 123  MET D CE  1 
ATOM   848  N N   . SER A 1 124 ? 237.764 231.086 131.595 1.00 61.13  ? 124  SER D N   1 
ATOM   849  C CA  . SER A 1 124 ? 237.633 231.813 132.852 1.00 61.13  ? 124  SER D CA  1 
ATOM   850  C C   . SER A 1 124 ? 238.680 232.915 132.962 1.00 61.13  ? 124  SER D C   1 
ATOM   851  O O   . SER A 1 124 ? 238.384 234.016 133.440 1.00 61.13  ? 124  SER D O   1 
ATOM   852  C CB  . SER A 1 124 ? 237.742 230.847 134.031 1.00 61.13  ? 124  SER D CB  1 
ATOM   853  O OG  . SER A 1 124 ? 237.628 231.532 135.266 1.00 61.13  ? 124  SER D OG  1 
ATOM   854  N N   . THR A 1 125 ? 239.908 232.642 132.514 1.00 64.48  ? 125  THR D N   1 
ATOM   855  C CA  . THR A 1 125 ? 240.952 233.660 132.580 1.00 64.48  ? 125  THR D CA  1 
ATOM   856  C C   . THR A 1 125 ? 240.701 234.781 131.577 1.00 64.48  ? 125  THR D C   1 
ATOM   857  O O   . THR A 1 125 ? 240.953 235.953 131.877 1.00 64.48  ? 125  THR D O   1 
ATOM   858  C CB  . THR A 1 125 ? 242.327 233.033 132.346 1.00 64.48  ? 125  THR D CB  1 
ATOM   859  O OG1 . THR A 1 125 ? 242.324 232.312 131.108 1.00 64.48  ? 125  THR D OG1 1 
ATOM   860  C CG2 . THR A 1 125 ? 242.686 232.091 133.486 1.00 64.48  ? 125  THR D CG2 1 
ATOM   861  N N   . ILE A 1 126 ? 240.213 234.444 130.380 1.00 63.69  ? 126  ILE D N   1 
ATOM   862  C CA  . ILE A 1 126 ? 239.903 235.471 129.389 1.00 63.69  ? 126  ILE D CA  1 
ATOM   863  C C   . ILE A 1 126 ? 238.789 236.378 129.894 1.00 63.69  ? 126  ILE D C   1 
ATOM   864  O O   . ILE A 1 126 ? 238.840 237.603 129.724 1.00 63.69  ? 126  ILE D O   1 
ATOM   865  C CB  . ILE A 1 126 ? 239.545 234.824 128.038 1.00 63.69  ? 126  ILE D CB  1 
ATOM   866  C CG1 . ILE A 1 126 ? 240.797 234.251 127.372 1.00 63.69  ? 126  ILE D CG1 1 
ATOM   867  C CG2 . ILE A 1 126 ? 238.874 235.830 127.117 1.00 63.69  ? 126  ILE D CG2 1 
ATOM   868  C CD1 . ILE A 1 126 ? 240.533 233.605 126.030 1.00 63.69  ? 126  ILE D CD1 1 
ATOM   869  N N   . TYR A 1 127 ? 237.770 235.797 130.532 1.00 63.25  ? 127  TYR D N   1 
ATOM   870  C CA  . TYR A 1 127 ? 236.687 236.617 131.066 1.00 63.25  ? 127  TYR D CA  1 
ATOM   871  C C   . TYR A 1 127 ? 237.155 237.453 132.251 1.00 63.25  ? 127  TYR D C   1 
ATOM   872  O O   . TYR A 1 127 ? 236.798 238.631 132.365 1.00 63.25  ? 127  TYR D O   1 
ATOM   873  C CB  . TYR A 1 127 ? 235.502 235.738 131.465 1.00 63.25  ? 127  TYR D CB  1 
ATOM   874  C CG  . TYR A 1 127 ? 234.306 236.526 131.951 1.00 63.25  ? 127  TYR D CG  1 
ATOM   875  C CD1 . TYR A 1 127 ? 233.400 237.072 131.052 1.00 63.25  ? 127  TYR D CD1 1 
ATOM   876  C CD2 . TYR A 1 127 ? 234.085 236.728 133.307 1.00 63.25  ? 127  TYR D CD2 1 
ATOM   877  C CE1 . TYR A 1 127 ? 232.307 237.795 131.489 1.00 63.25  ? 127  TYR D CE1 1 
ATOM   878  C CE2 . TYR A 1 127 ? 232.996 237.451 133.753 1.00 63.25  ? 127  TYR D CE2 1 
ATOM   879  C CZ  . TYR A 1 127 ? 232.111 237.981 132.841 1.00 63.25  ? 127  TYR D CZ  1 
ATOM   880  O OH  . TYR A 1 127 ? 231.023 238.700 133.281 1.00 63.25  ? 127  TYR D OH  1 
ATOM   881  N N   . SER A 1 128 ? 237.956 236.865 133.142 1.00 66.38  ? 128  SER D N   1 
ATOM   882  C CA  . SER A 1 128 ? 238.434 237.599 134.310 1.00 66.38  ? 128  SER D CA  1 
ATOM   883  C C   . SER A 1 128 ? 239.524 238.591 133.923 1.00 66.38  ? 128  SER D C   1 
ATOM   884  O O   . SER A 1 128 ? 239.386 239.801 134.135 1.00 66.38  ? 128  SER D O   1 
ATOM   885  C CB  . SER A 1 128 ? 238.941 236.621 135.371 1.00 66.38  ? 128  SER D CB  1 
ATOM   886  O OG  . SER A 1 128 ? 237.908 235.750 135.797 1.00 66.38  ? 128  SER D OG  1 
ATOM   887  N N   . THR A 1 129 ? 240.619 238.095 133.351 1.00 72.58  ? 129  THR D N   1 
ATOM   888  C CA  . THR A 1 129 ? 241.724 238.952 132.922 1.00 72.58  ? 129  THR D CA  1 
ATOM   889  C C   . THR A 1 129 ? 241.469 239.471 131.505 1.00 72.58  ? 129  THR D C   1 
ATOM   890  O O   . THR A 1 129 ? 242.203 239.197 130.556 1.00 72.58  ? 129  THR D O   1 
ATOM   891  C CB  . THR A 1 129 ? 243.047 238.199 133.013 1.00 72.58  ? 129  THR D CB  1 
ATOM   892  O OG1 . THR A 1 129 ? 243.088 237.453 134.236 1.00 72.58  ? 129  THR D OG1 1 
ATOM   893  C CG2 . THR A 1 129 ? 244.219 239.172 132.990 1.00 72.58  ? 129  THR D CG2 1 
ATOM   894  N N   . GLY A 1 130 ? 240.384 240.229 131.379 1.00 77.07  ? 130  GLY D N   1 
ATOM   895  C CA  . GLY A 1 130 ? 240.021 240.830 130.112 1.00 77.07  ? 130  GLY D CA  1 
ATOM   896  C C   . GLY A 1 130 ? 240.074 242.341 130.163 1.00 77.07  ? 130  GLY D C   1 
ATOM   897  O O   . GLY A 1 130 ? 239.263 242.976 130.844 1.00 77.07  ? 130  GLY D O   1 
ATOM   898  N N   . LYS A 1 131 ? 241.025 242.930 129.446 1.00 92.31  ? 131  LYS D N   1 
ATOM   899  C CA  . LYS A 1 131 ? 241.230 244.368 129.450 1.00 92.31  ? 131  LYS D CA  1 
ATOM   900  C C   . LYS A 1 131 ? 240.971 244.940 128.064 1.00 92.31  ? 131  LYS D C   1 
ATOM   901  O O   . LYS A 1 131 ? 241.052 244.240 127.050 1.00 92.31  ? 131  LYS D O   1 
ATOM   902  C CB  . LYS A 1 131 ? 242.651 244.726 129.905 1.00 92.31  ? 131  LYS D CB  1 
ATOM   903  C CG  . LYS A 1 131 ? 242.995 244.248 131.305 1.00 92.31  ? 131  LYS D CG  1 
ATOM   904  C CD  . LYS A 1 131 ? 244.419 244.623 131.682 1.00 92.31  ? 131  LYS D CD  1 
ATOM   905  C CE  . LYS A 1 131 ? 244.624 246.128 131.636 1.00 92.31  ? 131  LYS D CE  1 
ATOM   906  N NZ  . LYS A 1 131 ? 243.714 246.841 132.575 1.00 92.31  ? 131  LYS D NZ  1 
ATOM   907  N N   . VAL A 1 132 ? 240.654 246.231 128.035 1.00 100.88 ? 132  VAL D N   1 
ATOM   908  C CA  . VAL A 1 132 ? 240.430 246.965 126.796 1.00 100.88 ? 132  VAL D CA  1 
ATOM   909  C C   . VAL A 1 132 ? 240.955 248.380 126.984 1.00 100.88 ? 132  VAL D C   1 
ATOM   910  O O   . VAL A 1 132 ? 240.605 249.055 127.958 1.00 100.88 ? 132  VAL D O   1 
ATOM   911  C CB  . VAL A 1 132 ? 238.942 246.980 126.393 1.00 100.88 ? 132  VAL D CB  1 
ATOM   912  C CG1 . VAL A 1 132 ? 238.058 247.227 127.607 1.00 100.88 ? 132  VAL D CG1 1 
ATOM   913  C CG2 . VAL A 1 132 ? 238.696 248.033 125.327 1.00 100.88 ? 132  VAL D CG2 1 
ATOM   914  N N   . CYS A 1 133 ? 241.802 248.825 126.063 1.00 118.73 ? 133  CYS D N   1 
ATOM   915  C CA  . CYS A 1 133 ? 242.429 250.133 126.154 1.00 118.73 ? 133  CYS D CA  1 
ATOM   916  C C   . CYS A 1 133 ? 241.745 251.122 125.219 1.00 118.73 ? 133  CYS D C   1 
ATOM   917  O O   . CYS A 1 133 ? 241.220 250.751 124.166 1.00 118.73 ? 133  CYS D O   1 
ATOM   918  C CB  . CYS A 1 133 ? 243.920 250.047 125.824 1.00 118.73 ? 133  CYS D CB  1 
ATOM   919  S SG  . CYS A 1 133 ? 244.985 250.763 127.093 1.00 118.73 ? 133  CYS D SG  1 
ATOM   920  N N   . ASN A 1 134 ? 241.755 252.388 125.621 1.00 123.25 ? 134  ASN D N   1 
ATOM   921  C CA  . ASN A 1 134 ? 241.135 253.428 124.816 1.00 123.25 ? 134  ASN D CA  1 
ATOM   922  C C   . ASN A 1 134 ? 241.935 253.646 123.533 1.00 123.25 ? 134  ASN D C   1 
ATOM   923  O O   . ASN A 1 134 ? 243.165 253.535 123.541 1.00 123.25 ? 134  ASN D O   1 
ATOM   924  C CB  . ASN A 1 134 ? 241.046 254.734 125.604 1.00 123.25 ? 134  ASN D CB  1 
ATOM   925  C CG  . ASN A 1 134 ? 240.263 254.586 126.892 1.00 123.25 ? 134  ASN D CG  1 
ATOM   926  O OD1 . ASN A 1 134 ? 240.812 254.205 127.926 1.00 123.25 ? 134  ASN D OD1 1 
ATOM   927  N ND2 . ASN A 1 134 ? 238.972 254.892 126.839 1.00 123.25 ? 134  ASN D ND2 1 
ATOM   928  N N   . PRO A 1 135 ? 241.269 253.952 122.416 1.00 125.82 ? 135  PRO D N   1 
ATOM   929  C CA  . PRO A 1 135 ? 242.011 254.209 121.172 1.00 125.82 ? 135  PRO D CA  1 
ATOM   930  C C   . PRO A 1 135 ? 242.849 255.473 121.218 1.00 125.82 ? 135  PRO D C   1 
ATOM   931  O O   . PRO A 1 135 ? 243.814 255.583 120.451 1.00 125.82 ? 135  PRO D O   1 
ATOM   932  C CB  . PRO A 1 135 ? 240.902 254.313 120.117 1.00 125.82 ? 135  PRO D CB  1 
ATOM   933  C CG  . PRO A 1 135 ? 239.696 254.741 120.888 1.00 125.82 ? 135  PRO D CG  1 
ATOM   934  C CD  . PRO A 1 135 ? 239.813 254.077 122.231 1.00 125.82 ? 135  PRO D CD  1 
ATOM   935  N N   . ASP A 1 136 ? 242.517 256.427 122.089 1.00 134.75 ? 136  ASP D N   1 
ATOM   936  C CA  . ASP A 1 136 ? 243.279 257.661 122.211 1.00 134.75 ? 136  ASP D CA  1 
ATOM   937  C C   . ASP A 1 136 ? 244.217 257.676 123.410 1.00 134.75 ? 136  ASP D C   1 
ATOM   938  O O   . ASP A 1 136 ? 245.121 258.518 123.457 1.00 134.75 ? 136  ASP D O   1 
ATOM   939  C CB  . ASP A 1 136 ? 242.331 258.864 122.300 1.00 134.75 ? 136  ASP D CB  1 
ATOM   940  C CG  . ASP A 1 136 ? 241.263 258.688 123.362 1.00 134.75 ? 136  ASP D CG  1 
ATOM   941  O OD1 . ASP A 1 136 ? 241.190 257.595 123.961 1.00 134.75 ? 136  ASP D OD1 1 
ATOM   942  O OD2 . ASP A 1 136 ? 240.495 259.645 123.598 1.00 134.75 ? 136  ASP D OD2 1 
ATOM   943  N N   . ASN A 1 137 ? 244.029 256.774 124.373 1.00 134.91 ? 137  ASN D N   1 
ATOM   944  C CA  . ASN A 1 137 ? 244.867 256.696 125.570 1.00 134.91 ? 137  ASN D CA  1 
ATOM   945  C C   . ASN A 1 137 ? 245.355 255.263 125.734 1.00 134.91 ? 137  ASN D C   1 
ATOM   946  O O   . ASN A 1 137 ? 244.811 254.496 126.540 1.00 134.91 ? 137  ASN D O   1 
ATOM   947  C CB  . ASN A 1 137 ? 244.105 257.166 126.810 1.00 134.91 ? 137  ASN D CB  1 
ATOM   948  C CG  . ASN A 1 137 ? 243.635 258.602 126.696 1.00 134.91 ? 137  ASN D CG  1 
ATOM   949  O OD1 . ASN A 1 137 ? 242.522 258.868 126.243 1.00 134.91 ? 137  ASN D OD1 1 
ATOM   950  N ND2 . ASN A 1 137 ? 244.483 259.537 127.107 1.00 134.91 ? 137  ASN D ND2 1 
ATOM   951  N N   . PRO A 1 138 ? 246.386 254.865 124.981 1.00 135.47 ? 138  PRO D N   1 
ATOM   952  C CA  . PRO A 1 138 ? 246.910 253.496 125.113 1.00 135.47 ? 138  PRO D CA  1 
ATOM   953  C C   . PRO A 1 138 ? 247.644 253.242 126.419 1.00 135.47 ? 138  PRO D C   1 
ATOM   954  O O   . PRO A 1 138 ? 247.888 252.074 126.750 1.00 135.47 ? 138  PRO D O   1 
ATOM   955  C CB  . PRO A 1 138 ? 247.862 253.364 123.914 1.00 135.47 ? 138  PRO D CB  1 
ATOM   956  C CG  . PRO A 1 138 ? 247.506 254.499 122.993 1.00 135.47 ? 138  PRO D CG  1 
ATOM   957  C CD  . PRO A 1 138 ? 247.040 255.600 123.888 1.00 135.47 ? 138  PRO D CD  1 
ATOM   958  N N   . GLN A 1 139 ? 248.007 254.285 127.166 1.00 139.60 ? 139  GLN D N   1 
ATOM   959  C CA  . GLN A 1 139 ? 248.734 254.110 128.416 1.00 139.60 ? 139  GLN D CA  1 
ATOM   960  C C   . GLN A 1 139 ? 247.835 253.709 129.578 1.00 139.60 ? 139  GLN D C   1 
ATOM   961  O O   . GLN A 1 139 ? 248.350 253.286 130.619 1.00 139.60 ? 139  GLN D O   1 
ATOM   962  C CB  . GLN A 1 139 ? 249.488 255.394 128.775 1.00 139.60 ? 139  GLN D CB  1 
ATOM   963  C CG  . GLN A 1 139 ? 248.598 256.562 129.185 1.00 139.60 ? 139  GLN D CG  1 
ATOM   964  C CD  . GLN A 1 139 ? 247.908 257.226 128.007 1.00 139.60 ? 139  GLN D CD  1 
ATOM   965  O OE1 . GLN A 1 139 ? 248.181 256.906 126.850 1.00 139.60 ? 139  GLN D OE1 1 
ATOM   966  N NE2 . GLN A 1 139 ? 247.007 258.157 128.298 1.00 139.60 ? 139  GLN D NE2 1 
ATOM   967  N N   . GLU A 1 140 ? 246.517 253.830 129.432 1.00 132.76 ? 140  GLU D N   1 
ATOM   968  C CA  . GLU A 1 140 ? 245.578 253.473 130.490 1.00 132.76 ? 140  GLU D CA  1 
ATOM   969  C C   . GLU A 1 140 ? 244.438 252.676 129.878 1.00 132.76 ? 140  GLU D C   1 
ATOM   970  O O   . GLU A 1 140 ? 243.698 253.197 129.037 1.00 132.76 ? 140  GLU D O   1 
ATOM   971  C CB  . GLU A 1 140 ? 245.044 254.719 131.202 1.00 132.76 ? 140  GLU D CB  1 
ATOM   972  C CG  . GLU A 1 140 ? 244.051 254.421 132.313 1.00 132.76 ? 140  GLU D CG  1 
ATOM   973  C CD  . GLU A 1 140 ? 243.542 255.677 132.993 1.00 132.76 ? 140  GLU D CD  1 
ATOM   974  O OE1 . GLU A 1 140 ? 243.965 256.783 132.595 1.00 132.76 ? 140  GLU D OE1 1 
ATOM   975  O OE2 . GLU A 1 140 ? 242.720 255.558 133.926 1.00 132.76 ? 140  GLU D OE2 1 
ATOM   976  N N   . CYS A 1 141 ? 244.298 251.423 130.295 1.00 116.84 ? 141  CYS D N   1 
ATOM   977  C CA  . CYS A 1 141 ? 243.257 250.544 129.789 1.00 116.84 ? 141  CYS D CA  1 
ATOM   978  C C   . CYS A 1 141 ? 242.139 250.395 130.817 1.00 116.84 ? 141  CYS D C   1 
ATOM   979  O O   . CYS A 1 141 ? 242.276 250.764 131.985 1.00 116.84 ? 141  CYS D O   1 
ATOM   980  C CB  . CYS A 1 141 ? 243.837 249.175 129.422 1.00 116.84 ? 141  CYS D CB  1 
ATOM   981  S SG  . CYS A 1 141 ? 245.325 249.238 128.392 1.00 116.84 ? 141  CYS D SG  1 
ATOM   982  N N   . LEU A 1 142 ? 241.019 249.842 130.362 1.00 96.18  ? 142  LEU D N   1 
ATOM   983  C CA  . LEU A 1 142 ? 239.824 249.695 131.179 1.00 96.18  ? 142  LEU D CA  1 
ATOM   984  C C   . LEU A 1 142 ? 239.563 248.226 131.479 1.00 96.18  ? 142  LEU D C   1 
ATOM   985  O O   . LEU A 1 142 ? 239.664 247.372 130.593 1.00 96.18  ? 142  LEU D O   1 
ATOM   986  C CB  . LEU A 1 142 ? 238.605 250.306 130.481 1.00 96.18  ? 142  LEU D CB  1 
ATOM   987  C CG  . LEU A 1 142 ? 238.694 251.792 130.131 1.00 96.18  ? 142  LEU D CG  1 
ATOM   988  C CD1 . LEU A 1 142 ? 237.422 252.256 129.442 1.00 96.18  ? 142  LEU D CD1 1 
ATOM   989  C CD2 . LEU A 1 142 ? 238.968 252.622 131.375 1.00 96.18  ? 142  LEU D CD2 1 
ATOM   990  N N   . LEU A 1 143 ? 239.224 247.941 132.731 1.00 81.89  ? 143  LEU D N   1 
ATOM   991  C CA  . LEU A 1 143 ? 238.838 246.608 133.165 1.00 81.89  ? 143  LEU D CA  1 
ATOM   992  C C   . LEU A 1 143 ? 237.320 246.527 133.276 1.00 81.89  ? 143  LEU D C   1 
ATOM   993  O O   . LEU A 1 143 ? 236.623 247.544 133.317 1.00 81.89  ? 143  LEU D O   1 
ATOM   994  C CB  . LEU A 1 143 ? 239.497 246.264 134.505 1.00 81.89  ? 143  LEU D CB  1 
ATOM   995  C CG  . LEU A 1 143 ? 239.782 244.792 134.813 1.00 81.89  ? 143  LEU D CG  1 
ATOM   996  C CD1 . LEU A 1 143 ? 241.142 244.650 135.476 1.00 81.89  ? 143  LEU D CD1 1 
ATOM   997  C CD2 . LEU A 1 143 ? 238.701 244.194 135.699 1.00 81.89  ? 143  LEU D CD2 1 
ATOM   998  N N   . LEU A 1 144 ? 236.811 245.295 133.315 1.00 75.11  ? 144  LEU D N   1 
ATOM   999  C CA  . LEU A 1 144 ? 235.370 245.069 133.334 1.00 75.11  ? 144  LEU D CA  1 
ATOM   1000 C C   . LEU A 1 144 ? 234.728 245.696 134.565 1.00 75.11  ? 144  LEU D C   1 
ATOM   1001 O O   . LEU A 1 144 ? 233.969 246.663 134.445 1.00 75.11  ? 144  LEU D O   1 
ATOM   1002 C CB  . LEU A 1 144 ? 235.067 243.568 133.295 1.00 75.11  ? 144  LEU D CB  1 
ATOM   1003 C CG  . LEU A 1 144 ? 233.838 243.057 132.532 1.00 75.11  ? 144  LEU D CG  1 
ATOM   1004 C CD1 . LEU A 1 144 ? 233.501 241.641 132.977 1.00 75.11  ? 144  LEU D CD1 1 
ATOM   1005 C CD2 . LEU A 1 144 ? 232.626 243.968 132.679 1.00 75.11  ? 144  LEU D CD2 1 
ATOM   1006 N N   . GLU A 1 145 ? 235.064 245.180 135.748 1.00 79.30  ? 145  GLU D N   1 
ATOM   1007 C CA  . GLU A 1 145 ? 234.355 245.574 136.964 1.00 79.30  ? 145  GLU D CA  1 
ATOM   1008 C C   . GLU A 1 145 ? 234.479 247.061 137.279 1.00 79.30  ? 145  GLU D C   1 
ATOM   1009 O O   . GLU A 1 145 ? 233.438 247.713 137.470 1.00 79.30  ? 145  GLU D O   1 
ATOM   1010 C CB  . GLU A 1 145 ? 234.829 244.704 138.135 1.00 79.30  ? 145  GLU D CB  1 
ATOM   1011 C CG  . GLU A 1 145 ? 234.035 244.881 139.423 1.00 79.30  ? 145  GLU D CG  1 
ATOM   1012 C CD  . GLU A 1 145 ? 234.572 245.996 140.301 1.00 79.30  ? 145  GLU D CD  1 
ATOM   1013 O OE1 . GLU A 1 145 ? 235.714 246.442 140.067 1.00 79.30  ? 145  GLU D OE1 1 
ATOM   1014 O OE2 . GLU A 1 145 ? 233.850 246.426 141.225 1.00 79.30  ? 145  GLU D OE2 1 
ATOM   1015 N N   . PRO A 1 146 ? 235.673 247.661 137.353 1.00 78.32  ? 146  PRO D N   1 
ATOM   1016 C CA  . PRO A 1 146 ? 235.717 249.082 137.734 1.00 78.32  ? 146  PRO D CA  1 
ATOM   1017 C C   . PRO A 1 146 ? 235.274 250.020 136.625 1.00 78.32  ? 146  PRO D C   1 
ATOM   1018 O O   . PRO A 1 146 ? 234.588 251.012 136.902 1.00 78.32  ? 146  PRO D O   1 
ATOM   1019 C CB  . PRO A 1 146 ? 237.189 249.293 138.110 1.00 78.32  ? 146  PRO D CB  1 
ATOM   1020 C CG  . PRO A 1 146 ? 237.919 248.327 137.258 1.00 78.32  ? 146  PRO D CG  1 
ATOM   1021 C CD  . PRO A 1 146 ? 237.029 247.117 137.140 1.00 78.32  ? 146  PRO D CD  1 
ATOM   1022 N N   . GLY A 1 147 ? 235.642 249.740 135.378 1.00 75.78  ? 147  GLY D N   1 
ATOM   1023 C CA  . GLY A 1 147 ? 235.383 250.675 134.301 1.00 75.78  ? 147  GLY D CA  1 
ATOM   1024 C C   . GLY A 1 147 ? 234.152 250.406 133.459 1.00 75.78  ? 147  GLY D C   1 
ATOM   1025 O O   . GLY A 1 147 ? 233.334 251.308 133.252 1.00 75.78  ? 147  GLY D O   1 
ATOM   1026 N N   . LEU A 1 148 ? 234.003 249.173 132.969 1.00 72.91  ? 148  LEU D N   1 
ATOM   1027 C CA  . LEU A 1 148 ? 232.949 248.898 131.997 1.00 72.91  ? 148  LEU D CA  1 
ATOM   1028 C C   . LEU A 1 148 ? 231.571 248.937 132.643 1.00 72.91  ? 148  LEU D C   1 
ATOM   1029 O O   . LEU A 1 148 ? 230.628 249.494 132.069 1.00 72.91  ? 148  LEU D O   1 
ATOM   1030 C CB  . LEU A 1 148 ? 233.192 247.548 131.321 1.00 72.91  ? 148  LEU D CB  1 
ATOM   1031 C CG  . LEU A 1 148 ? 234.014 247.567 130.029 1.00 72.91  ? 148  LEU D CG  1 
ATOM   1032 C CD1 . LEU A 1 148 ? 235.438 248.041 130.276 1.00 72.91  ? 148  LEU D CD1 1 
ATOM   1033 C CD2 . LEU A 1 148 ? 234.011 246.195 129.376 1.00 72.91  ? 148  LEU D CD2 1 
ATOM   1034 N N   . ASN A 1 149 ? 231.433 248.348 133.833 1.00 73.04  ? 149  ASN D N   1 
ATOM   1035 C CA  . ASN A 1 149 ? 230.156 248.410 134.536 1.00 73.04  ? 149  ASN D CA  1 
ATOM   1036 C C   . ASN A 1 149 ? 229.794 249.847 134.886 1.00 73.04  ? 149  ASN D C   1 
ATOM   1037 O O   . ASN A 1 149 ? 228.632 250.250 134.760 1.00 73.04  ? 149  ASN D O   1 
ATOM   1038 C CB  . ASN A 1 149 ? 230.204 247.543 135.794 1.00 73.04  ? 149  ASN D CB  1 
ATOM   1039 C CG  . ASN A 1 149 ? 230.326 246.066 135.479 1.00 73.04  ? 149  ASN D CG  1 
ATOM   1040 O OD1 . ASN A 1 149 ? 231.240 245.392 135.953 1.00 73.04  ? 149  ASN D OD1 1 
ATOM   1041 N ND2 . ASN A 1 149 ? 229.403 245.555 134.674 1.00 73.04  ? 149  ASN D ND2 1 
ATOM   1042 N N   . GLU A 1 150 ? 230.780 250.639 135.313 1.00 73.30  ? 150  GLU D N   1 
ATOM   1043 C CA  . GLU A 1 150 ? 230.520 252.039 135.629 1.00 73.30  ? 150  GLU D CA  1 
ATOM   1044 C C   . GLU A 1 150 ? 230.060 252.807 134.396 1.00 73.30  ? 150  GLU D C   1 
ATOM   1045 O O   . GLU A 1 150 ? 229.117 253.604 134.468 1.00 73.30  ? 150  GLU D O   1 
ATOM   1046 C CB  . GLU A 1 150 ? 231.773 252.681 136.225 1.00 73.30  ? 150  GLU D CB  1 
ATOM   1047 C CG  . GLU A 1 150 ? 231.596 254.132 136.640 1.00 73.30  ? 150  GLU D CG  1 
ATOM   1048 C CD  . GLU A 1 150 ? 230.703 254.290 137.856 1.00 73.30  ? 150  GLU D CD  1 
ATOM   1049 O OE1 . GLU A 1 150 ? 230.520 253.301 138.597 1.00 73.30  ? 150  GLU D OE1 1 
ATOM   1050 O OE2 . GLU A 1 150 ? 230.183 255.405 138.071 1.00 73.30  ? 150  GLU D OE2 1 
ATOM   1051 N N   . ILE A 1 151 ? 230.708 252.572 133.252 1.00 70.30  ? 151  ILE D N   1 
ATOM   1052 C CA  . ILE A 1 151 ? 230.321 253.260 132.024 1.00 70.30  ? 151  ILE D CA  1 
ATOM   1053 C C   . ILE A 1 151 ? 228.921 252.841 131.591 1.00 70.30  ? 151  ILE D C   1 
ATOM   1054 O O   . ILE A 1 151 ? 228.105 253.679 131.189 1.00 70.30  ? 151  ILE D O   1 
ATOM   1055 C CB  . ILE A 1 151 ? 231.360 253.003 130.917 1.00 70.30  ? 151  ILE D CB  1 
ATOM   1056 C CG1 . ILE A 1 151 ? 232.679 253.702 131.250 1.00 70.30  ? 151  ILE D CG1 1 
ATOM   1057 C CG2 . ILE A 1 151 ? 230.838 253.471 129.568 1.00 70.30  ? 151  ILE D CG2 1 
ATOM   1058 C CD1 . ILE A 1 151 ? 233.754 253.504 130.205 1.00 70.30  ? 151  ILE D CD1 1 
ATOM   1059 N N   . MET A 1 152 ? 228.613 251.547 131.672 1.00 68.89  ? 152  MET D N   1 
ATOM   1060 C CA  . MET A 1 152 ? 227.306 251.072 131.235 1.00 68.89  ? 152  MET D CA  1 
ATOM   1061 C C   . MET A 1 152 ? 226.192 251.412 132.216 1.00 68.89  ? 152  MET D C   1 
ATOM   1062 O O   . MET A 1 152 ? 225.018 251.370 131.832 1.00 68.89  ? 152  MET D O   1 
ATOM   1063 C CB  . MET A 1 152 ? 227.344 249.559 131.007 1.00 68.89  ? 152  MET D CB  1 
ATOM   1064 C CG  . MET A 1 152 ? 228.274 249.124 129.887 1.00 68.89  ? 152  MET D CG  1 
ATOM   1065 S SD  . MET A 1 152 ? 227.875 249.898 128.309 1.00 68.89  ? 152  MET D SD  1 
ATOM   1066 C CE  . MET A 1 152 ? 226.194 249.330 128.068 1.00 68.89  ? 152  MET D CE  1 
ATOM   1067 N N   . ALA A 1 153 ? 226.523 251.749 133.462 1.00 68.32  ? 153  ALA D N   1 
ATOM   1068 C CA  . ALA A 1 153 ? 225.511 252.038 134.469 1.00 68.32  ? 153  ALA D CA  1 
ATOM   1069 C C   . ALA A 1 153 ? 225.275 253.530 134.678 1.00 68.32  ? 153  ALA D C   1 
ATOM   1070 O O   . ALA A 1 153 ? 224.132 253.989 134.602 1.00 68.32  ? 153  ALA D O   1 
ATOM   1071 C CB  . ALA A 1 153 ? 225.899 251.384 135.800 1.00 68.32  ? 153  ALA D CB  1 
ATOM   1072 N N   . ASN A 1 154 ? 226.329 254.301 134.941 1.00 72.17  ? 154  ASN D N   1 
ATOM   1073 C CA  . ASN A 1 154 ? 226.178 255.683 135.377 1.00 72.17  ? 154  ASN D CA  1 
ATOM   1074 C C   . ASN A 1 154 ? 226.434 256.707 134.278 1.00 72.17  ? 154  ASN D C   1 
ATOM   1075 O O   . ASN A 1 154 ? 226.321 257.909 134.539 1.00 72.17  ? 154  ASN D O   1 
ATOM   1076 C CB  . ASN A 1 154 ? 227.107 255.963 136.564 1.00 72.17  ? 154  ASN D CB  1 
ATOM   1077 C CG  . ASN A 1 154 ? 226.736 255.158 137.793 1.00 72.17  ? 154  ASN D CG  1 
ATOM   1078 O OD1 . ASN A 1 154 ? 225.589 254.745 137.956 1.00 72.17  ? 154  ASN D OD1 1 
ATOM   1079 N ND2 . ASN A 1 154 ? 227.708 254.935 138.670 1.00 72.17  ? 154  ASN D ND2 1 
ATOM   1080 N N   . SER A 1 155 ? 226.771 256.277 133.068 1.00 70.63  ? 155  SER D N   1 
ATOM   1081 C CA  . SER A 1 155 ? 227.007 257.199 131.967 1.00 70.63  ? 155  SER D CA  1 
ATOM   1082 C C   . SER A 1 155 ? 225.780 257.281 131.067 1.00 70.63  ? 155  SER D C   1 
ATOM   1083 O O   . SER A 1 155 ? 225.022 256.318 130.928 1.00 70.63  ? 155  SER D O   1 
ATOM   1084 C CB  . SER A 1 155 ? 228.228 256.780 131.147 1.00 70.63  ? 155  SER D CB  1 
ATOM   1085 O OG  . SER A 1 155 ? 229.396 256.753 131.949 1.00 70.63  ? 155  SER D OG  1 
ATOM   1086 N N   . LEU A 1 156 ? 225.594 258.450 130.454 1.00 68.90  ? 156  LEU D N   1 
ATOM   1087 C CA  . LEU A 1 156 ? 224.450 258.704 129.592 1.00 68.90  ? 156  LEU D CA  1 
ATOM   1088 C C   . LEU A 1 156 ? 224.827 258.974 128.142 1.00 68.90  ? 156  LEU D C   1 
ATOM   1089 O O   . LEU A 1 156 ? 223.931 259.050 127.294 1.00 68.90  ? 156  LEU D O   1 
ATOM   1090 C CB  . LEU A 1 156 ? 223.635 259.892 130.131 1.00 68.90  ? 156  LEU D CB  1 
ATOM   1091 C CG  . LEU A 1 156 ? 222.173 260.021 129.698 1.00 68.90  ? 156  LEU D CG  1 
ATOM   1092 C CD1 . LEU A 1 156 ? 221.377 258.804 130.141 1.00 68.90  ? 156  LEU D CD1 1 
ATOM   1093 C CD2 . LEU A 1 156 ? 221.559 261.297 130.251 1.00 68.90  ? 156  LEU D CD2 1 
ATOM   1094 N N   . ASP A 1 157 ? 226.114 259.108 127.830 1.00 74.31  ? 157  ASP D N   1 
ATOM   1095 C CA  . ASP A 1 157 ? 226.528 259.397 126.464 1.00 74.31  ? 157  ASP D CA  1 
ATOM   1096 C C   . ASP A 1 157 ? 226.304 258.178 125.577 1.00 74.31  ? 157  ASP D C   1 
ATOM   1097 O O   . ASP A 1 157 ? 226.695 257.061 125.926 1.00 74.31  ? 157  ASP D O   1 
ATOM   1098 C CB  . ASP A 1 157 ? 227.999 259.814 126.436 1.00 74.31  ? 157  ASP D CB  1 
ATOM   1099 C CG  . ASP A 1 157 ? 228.378 260.546 125.160 1.00 74.31  ? 157  ASP D CG  1 
ATOM   1100 O OD1 . ASP A 1 157 ? 227.737 260.311 124.115 1.00 74.31  ? 157  ASP D OD1 1 
ATOM   1101 O OD2 . ASP A 1 157 ? 229.323 261.361 125.205 1.00 74.31  ? 157  ASP D OD2 1 
ATOM   1102 N N   . TYR A 1 158 ? 225.672 258.399 124.423 1.00 70.59  ? 158  TYR D N   1 
ATOM   1103 C CA  . TYR A 1 158 ? 225.407 257.304 123.496 1.00 70.59  ? 158  TYR D CA  1 
ATOM   1104 C C   . TYR A 1 158 ? 226.701 256.760 122.903 1.00 70.59  ? 158  TYR D C   1 
ATOM   1105 O O   . TYR A 1 158 ? 226.901 255.541 122.832 1.00 70.59  ? 158  TYR D O   1 
ATOM   1106 C CB  . TYR A 1 158 ? 224.462 257.779 122.390 1.00 70.59  ? 158  TYR D CB  1 
ATOM   1107 C CG  . TYR A 1 158 ? 224.016 256.695 121.432 1.00 70.59  ? 158  TYR D CG  1 
ATOM   1108 C CD1 . TYR A 1 158 ? 224.758 256.392 120.297 1.00 70.59  ? 158  TYR D CD1 1 
ATOM   1109 C CD2 . TYR A 1 158 ? 222.845 255.984 121.656 1.00 70.59  ? 158  TYR D CD2 1 
ATOM   1110 C CE1 . TYR A 1 158 ? 224.351 255.406 119.419 1.00 70.59  ? 158  TYR D CE1 1 
ATOM   1111 C CE2 . TYR A 1 158 ? 222.429 254.997 120.783 1.00 70.59  ? 158  TYR D CE2 1 
ATOM   1112 C CZ  . TYR A 1 158 ? 223.186 254.712 119.667 1.00 70.59  ? 158  TYR D CZ  1 
ATOM   1113 O OH  . TYR A 1 158 ? 222.776 253.730 118.795 1.00 70.59  ? 158  TYR D OH  1 
ATOM   1114 N N   . ASN A 1 159 ? 227.595 257.655 122.473 1.00 72.41  ? 159  ASN D N   1 
ATOM   1115 C CA  . ASN A 1 159 ? 228.825 257.223 121.818 1.00 72.41  ? 159  ASN D CA  1 
ATOM   1116 C C   . ASN A 1 159 ? 229.727 256.454 122.774 1.00 72.41  ? 159  ASN D C   1 
ATOM   1117 O O   . ASN A 1 159 ? 230.321 255.440 122.391 1.00 72.41  ? 159  ASN D O   1 
ATOM   1118 C CB  . ASN A 1 159 ? 229.560 258.431 121.239 1.00 72.41  ? 159  ASN D CB  1 
ATOM   1119 C CG  . ASN A 1 159 ? 228.717 259.204 120.244 1.00 72.41  ? 159  ASN D CG  1 
ATOM   1120 O OD1 . ASN A 1 159 ? 228.714 258.903 119.051 1.00 72.41  ? 159  ASN D OD1 1 
ATOM   1121 N ND2 . ASN A 1 159 ? 227.996 260.206 120.733 1.00 72.41  ? 159  ASN D ND2 1 
ATOM   1122 N N   . GLU A 1 160 ? 229.839 256.915 124.022 1.00 73.44  ? 160  GLU D N   1 
ATOM   1123 C CA  . GLU A 1 160 ? 230.694 256.232 124.988 1.00 73.44  ? 160  GLU D CA  1 
ATOM   1124 C C   . GLU A 1 160 ? 230.173 254.835 125.302 1.00 73.44  ? 160  GLU D C   1 
ATOM   1125 O O   . GLU A 1 160 ? 230.948 253.871 125.345 1.00 73.44  ? 160  GLU D O   1 
ATOM   1126 C CB  . GLU A 1 160 ? 230.807 257.063 126.265 1.00 73.44  ? 160  GLU D CB  1 
ATOM   1127 C CG  . GLU A 1 160 ? 231.661 256.427 127.348 1.00 73.44  ? 160  GLU D CG  1 
ATOM   1128 C CD  . GLU A 1 160 ? 231.731 257.270 128.605 1.00 73.44  ? 160  GLU D CD  1 
ATOM   1129 O OE1 . GLU A 1 160 ? 231.107 258.352 128.632 1.00 73.44  ? 160  GLU D OE1 1 
ATOM   1130 O OE2 . GLU A 1 160 ? 232.411 256.852 129.566 1.00 73.44  ? 160  GLU D OE2 1 
ATOM   1131 N N   . ARG A 1 161 ? 228.863 254.706 125.525 1.00 70.28  ? 161  ARG D N   1 
ATOM   1132 C CA  . ARG A 1 161 ? 228.287 253.395 125.808 1.00 70.28  ? 161  ARG D CA  1 
ATOM   1133 C C   . ARG A 1 161 ? 228.410 252.468 124.607 1.00 70.28  ? 161  ARG D C   1 
ATOM   1134 O O   . ARG A 1 161 ? 228.691 251.274 124.765 1.00 70.28  ? 161  ARG D O   1 
ATOM   1135 C CB  . ARG A 1 161 ? 226.826 253.544 126.230 1.00 70.28  ? 161  ARG D CB  1 
ATOM   1136 C CG  . ARG A 1 161 ? 226.636 254.317 127.526 1.00 70.28  ? 161  ARG D CG  1 
ATOM   1137 C CD  . ARG A 1 161 ? 225.170 254.625 127.777 1.00 70.28  ? 161  ARG D CD  1 
ATOM   1138 N NE  . ARG A 1 161 ? 224.385 253.414 127.988 1.00 70.28  ? 161  ARG D NE  1 
ATOM   1139 C CZ  . ARG A 1 161 ? 224.106 252.905 129.183 1.00 70.28  ? 161  ARG D CZ  1 
ATOM   1140 N NH1 . ARG A 1 161 ? 223.384 251.798 129.281 1.00 70.28  ? 161  ARG D NH1 1 
ATOM   1141 N NH2 . ARG A 1 161 ? 224.547 253.504 130.280 1.00 70.28  ? 161  ARG D NH2 1 
ATOM   1142 N N   . LEU A 1 162 ? 228.211 252.998 123.397 1.00 71.23  ? 162  LEU D N   1 
ATOM   1143 C CA  . LEU A 1 162 ? 228.375 252.181 122.199 1.00 71.23  ? 162  LEU D CA  1 
ATOM   1144 C C   . LEU A 1 162 ? 229.814 251.702 122.057 1.00 71.23  ? 162  LEU D C   1 
ATOM   1145 O O   . LEU A 1 162 ? 230.058 250.533 121.731 1.00 71.23  ? 162  LEU D O   1 
ATOM   1146 C CB  . LEU A 1 162 ? 227.939 252.974 120.964 1.00 71.23  ? 162  LEU D CB  1 
ATOM   1147 C CG  . LEU A 1 162 ? 227.827 252.259 119.613 1.00 71.23  ? 162  LEU D CG  1 
ATOM   1148 C CD1 . LEU A 1 162 ? 229.143 252.290 118.842 1.00 71.23  ? 162  LEU D CD1 1 
ATOM   1149 C CD2 . LEU A 1 162 ? 227.347 250.828 119.798 1.00 71.23  ? 162  LEU D CD2 1 
ATOM   1150 N N   . TRP A 1 163 ? 230.780 252.592 122.299 1.00 78.84  ? 163  TRP D N   1 
ATOM   1151 C CA  . TRP A 1 163 ? 232.184 252.204 122.229 1.00 78.84  ? 163  TRP D CA  1 
ATOM   1152 C C   . TRP A 1 163 ? 232.511 251.130 123.256 1.00 78.84  ? 163  TRP D C   1 
ATOM   1153 O O   . TRP A 1 163 ? 233.190 250.148 122.940 1.00 78.84  ? 163  TRP D O   1 
ATOM   1154 C CB  . TRP A 1 163 ? 233.076 253.429 122.429 1.00 78.84  ? 163  TRP D CB  1 
ATOM   1155 C CG  . TRP A 1 163 ? 234.524 253.094 122.601 1.00 78.84  ? 163  TRP D CG  1 
ATOM   1156 C CD1 . TRP A 1 163 ? 235.447 252.913 121.612 1.00 78.84  ? 163  TRP D CD1 1 
ATOM   1157 C CD2 . TRP A 1 163 ? 235.220 252.901 123.838 1.00 78.84  ? 163  TRP D CD2 1 
ATOM   1158 N NE1 . TRP A 1 163 ? 236.673 252.618 122.157 1.00 78.84  ? 163  TRP D NE1 1 
ATOM   1159 C CE2 . TRP A 1 163 ? 236.560 252.605 123.522 1.00 78.84  ? 163  TRP D CE2 1 
ATOM   1160 C CE3 . TRP A 1 163 ? 234.839 252.949 125.182 1.00 78.84  ? 163  TRP D CE3 1 
ATOM   1161 C CZ2 . TRP A 1 163 ? 237.520 252.358 124.500 1.00 78.84  ? 163  TRP D CZ2 1 
ATOM   1162 C CZ3 . TRP A 1 163 ? 235.793 252.704 126.152 1.00 78.84  ? 163  TRP D CZ3 1 
ATOM   1163 C CH2 . TRP A 1 163 ? 237.118 252.412 125.806 1.00 78.84  ? 163  TRP D CH2 1 
ATOM   1164 N N   . ALA A 1 164 ? 232.032 251.297 124.492 1.00 72.61  ? 164  ALA D N   1 
ATOM   1165 C CA  . ALA A 1 164 ? 232.298 250.302 125.527 1.00 72.61  ? 164  ALA D CA  1 
ATOM   1166 C C   . ALA A 1 164 ? 231.685 248.954 125.170 1.00 72.61  ? 164  ALA D C   1 
ATOM   1167 O O   . ALA A 1 164 ? 232.331 247.908 125.321 1.00 72.61  ? 164  ALA D O   1 
ATOM   1168 C CB  . ALA A 1 164 ? 231.771 250.793 126.875 1.00 72.61  ? 164  ALA D CB  1 
ATOM   1169 N N   . TRP A 1 165 ? 230.440 248.958 124.687 1.00 68.58  ? 165  TRP D N   1 
ATOM   1170 C CA  . TRP A 1 165 ? 229.773 247.712 124.325 1.00 68.58  ? 165  TRP D CA  1 
ATOM   1171 C C   . TRP A 1 165 ? 230.502 247.011 123.185 1.00 68.58  ? 165  TRP D C   1 
ATOM   1172 O O   . TRP A 1 165 ? 230.754 245.800 123.245 1.00 68.58  ? 165  TRP D O   1 
ATOM   1173 C CB  . TRP A 1 165 ? 228.318 247.998 123.951 1.00 68.58  ? 165  TRP D CB  1 
ATOM   1174 C CG  . TRP A 1 165 ? 227.499 246.774 123.696 1.00 68.58  ? 165  TRP D CG  1 
ATOM   1175 C CD1 . TRP A 1 165 ? 226.886 245.990 124.627 1.00 68.58  ? 165  TRP D CD1 1 
ATOM   1176 C CD2 . TRP A 1 165 ? 227.192 246.199 122.421 1.00 68.58  ? 165  TRP D CD2 1 
ATOM   1177 N NE1 . TRP A 1 165 ? 226.220 244.958 124.013 1.00 68.58  ? 165  TRP D NE1 1 
ATOM   1178 C CE2 . TRP A 1 165 ? 226.392 245.064 122.658 1.00 68.58  ? 165  TRP D CE2 1 
ATOM   1179 C CE3 . TRP A 1 165 ? 227.517 246.531 121.103 1.00 68.58  ? 165  TRP D CE3 1 
ATOM   1180 C CZ2 . TRP A 1 165 ? 225.914 244.260 121.627 1.00 68.58  ? 165  TRP D CZ2 1 
ATOM   1181 C CZ3 . TRP A 1 165 ? 227.042 245.731 120.081 1.00 68.58  ? 165  TRP D CZ3 1 
ATOM   1182 C CH2 . TRP A 1 165 ? 226.248 244.609 120.348 1.00 68.58  ? 165  TRP D CH2 1 
ATOM   1183 N N   . GLU A 1 166 ? 230.857 247.760 122.137 1.00 72.46  ? 166  GLU D N   1 
ATOM   1184 C CA  . GLU A 1 166 ? 231.554 247.160 121.005 1.00 72.46  ? 166  GLU D CA  1 
ATOM   1185 C C   . GLU A 1 166 ? 232.927 246.641 121.413 1.00 72.46  ? 166  GLU D C   1 
ATOM   1186 O O   . GLU A 1 166 ? 233.349 245.568 120.968 1.00 72.46  ? 166  GLU D O   1 
ATOM   1187 C CB  . GLU A 1 166 ? 231.676 248.174 119.867 1.00 72.46  ? 166  GLU D CB  1 
ATOM   1188 C CG  . GLU A 1 166 ? 232.436 247.664 118.652 1.00 72.46  ? 166  GLU D CG  1 
ATOM   1189 C CD  . GLU A 1 166 ? 231.724 246.525 117.945 1.00 72.46  ? 166  GLU D CD  1 
ATOM   1190 O OE1 . GLU A 1 166 ? 230.495 246.386 118.118 1.00 72.46  ? 166  GLU D OE1 1 
ATOM   1191 O OE2 . GLU A 1 166 ? 232.396 245.766 117.216 1.00 72.46  ? 166  GLU D OE2 1 
ATOM   1192 N N   . SER A 1 167 ? 233.634 247.382 122.269 1.00 71.08  ? 167  SER D N   1 
ATOM   1193 C CA  . SER A 1 167 ? 234.948 246.939 122.718 1.00 71.08  ? 167  SER D CA  1 
ATOM   1194 C C   . SER A 1 167 ? 234.848 245.665 123.545 1.00 71.08  ? 167  SER D C   1 
ATOM   1195 O O   . SER A 1 167 ? 235.676 244.759 123.398 1.00 71.08  ? 167  SER D O   1 
ATOM   1196 C CB  . SER A 1 167 ? 235.627 248.049 123.518 1.00 71.08  ? 167  SER D CB  1 
ATOM   1197 O OG  . SER A 1 167 ? 235.807 249.211 122.727 1.00 71.08  ? 167  SER D OG  1 
ATOM   1198 N N   . TRP A 1 168 ? 233.839 245.571 124.414 1.00 67.21  ? 168  TRP D N   1 
ATOM   1199 C CA  . TRP A 1 168 ? 233.680 244.357 125.207 1.00 67.21  ? 168  TRP D CA  1 
ATOM   1200 C C   . TRP A 1 168 ? 233.279 243.174 124.335 1.00 67.21  ? 168  TRP D C   1 
ATOM   1201 O O   . TRP A 1 168 ? 233.717 242.043 124.577 1.00 67.21  ? 168  TRP D O   1 
ATOM   1202 C CB  . TRP A 1 168 ? 232.654 244.577 126.317 1.00 67.21  ? 168  TRP D CB  1 
ATOM   1203 C CG  . TRP A 1 168 ? 232.362 243.331 127.093 1.00 67.21  ? 168  TRP D CG  1 
ATOM   1204 C CD1 . TRP A 1 168 ? 231.194 242.627 127.103 1.00 67.21  ? 168  TRP D CD1 1 
ATOM   1205 C CD2 . TRP A 1 168 ? 233.262 242.627 127.957 1.00 67.21  ? 168  TRP D CD2 1 
ATOM   1206 N NE1 . TRP A 1 168 ? 231.307 241.535 127.929 1.00 67.21  ? 168  TRP D NE1 1 
ATOM   1207 C CE2 . TRP A 1 168 ? 232.568 241.511 128.464 1.00 67.21  ? 168  TRP D CE2 1 
ATOM   1208 C CE3 . TRP A 1 168 ? 234.586 242.834 128.354 1.00 67.21  ? 168  TRP D CE3 1 
ATOM   1209 C CZ2 . TRP A 1 168 ? 233.152 240.607 129.347 1.00 67.21  ? 168  TRP D CZ2 1 
ATOM   1210 C CZ3 . TRP A 1 168 ? 235.164 241.936 129.232 1.00 67.21  ? 168  TRP D CZ3 1 
ATOM   1211 C CH2 . TRP A 1 168 ? 234.448 240.835 129.716 1.00 67.21  ? 168  TRP D CH2 1 
ATOM   1212 N N   . ARG A 1 169 ? 232.451 243.409 123.315 1.00 67.13  ? 169  ARG D N   1 
ATOM   1213 C CA  . ARG A 1 169 ? 232.034 242.320 122.441 1.00 67.13  ? 169  ARG D CA  1 
ATOM   1214 C C   . ARG A 1 169 ? 233.120 241.896 121.460 1.00 67.13  ? 169  ARG D C   1 
ATOM   1215 O O   . ARG A 1 169 ? 233.082 240.762 120.972 1.00 67.13  ? 169  ARG D O   1 
ATOM   1216 C CB  . ARG A 1 169 ? 230.771 242.711 121.670 1.00 67.13  ? 169  ARG D CB  1 
ATOM   1217 C CG  . ARG A 1 169 ? 229.560 242.962 122.554 1.00 67.13  ? 169  ARG D CG  1 
ATOM   1218 C CD  . ARG A 1 169 ? 229.263 241.765 123.440 1.00 67.13  ? 169  ARG D CD  1 
ATOM   1219 N NE  . ARG A 1 169 ? 228.205 242.050 124.405 1.00 67.13  ? 169  ARG D NE  1 
ATOM   1220 C CZ  . ARG A 1 169 ? 226.912 241.841 124.180 1.00 67.13  ? 169  ARG D CZ  1 
ATOM   1221 N NH1 . ARG A 1 169 ? 226.019 242.129 125.116 1.00 67.13  ? 169  ARG D NH1 1 
ATOM   1222 N NH2 . ARG A 1 169 ? 226.511 241.344 123.018 1.00 67.13  ? 169  ARG D NH2 1 
ATOM   1223 N N   . SER A 1 170 ? 234.080 242.770 121.160 1.00 69.08  ? 170  SER D N   1 
ATOM   1224 C CA  . SER A 1 170 ? 235.130 242.459 120.197 1.00 69.08  ? 170  SER D CA  1 
ATOM   1225 C C   . SER A 1 170 ? 236.403 241.930 120.848 1.00 69.08  ? 170  SER D C   1 
ATOM   1226 O O   . SER A 1 170 ? 236.970 240.939 120.378 1.00 69.08  ? 170  SER D O   1 
ATOM   1227 C CB  . SER A 1 170 ? 235.456 243.704 119.362 1.00 69.08  ? 170  SER D CB  1 
ATOM   1228 O OG  . SER A 1 170 ? 234.306 244.177 118.682 1.00 69.08  ? 170  SER D OG  1 
ATOM   1229 N N   . GLU A 1 171 ? 236.869 242.571 121.923 1.00 70.74  ? 171  GLU D N   1 
ATOM   1230 C CA  . GLU A 1 171 ? 238.145 242.185 122.516 1.00 70.74  ? 171  GLU D CA  1 
ATOM   1231 C C   . GLU A 1 171 ? 238.064 240.838 123.222 1.00 70.74  ? 171  GLU D C   1 
ATOM   1232 O O   . GLU A 1 171 ? 239.057 240.103 123.263 1.00 70.74  ? 171  GLU D O   1 
ATOM   1233 C CB  . GLU A 1 171 ? 238.619 243.263 123.491 1.00 70.74  ? 171  GLU D CB  1 
ATOM   1234 C CG  . GLU A 1 171 ? 238.871 244.619 122.848 1.00 70.74  ? 171  GLU D CG  1 
ATOM   1235 C CD  . GLU A 1 171 ? 240.054 244.609 121.899 1.00 70.74  ? 171  GLU D CD  1 
ATOM   1236 O OE1 . GLU A 1 171 ? 240.934 243.734 122.047 1.00 70.74  ? 171  GLU D OE1 1 
ATOM   1237 O OE2 . GLU A 1 171 ? 240.103 245.476 121.002 1.00 70.74  ? 171  GLU D OE2 1 
ATOM   1238 N N   . VAL A 1 172 ? 236.905 240.496 123.777 1.00 67.22  ? 172  VAL D N   1 
ATOM   1239 C CA  . VAL A 1 172 ? 236.728 239.260 124.523 1.00 67.22  ? 172  VAL D CA  1 
ATOM   1240 C C   . VAL A 1 172 ? 235.826 238.280 123.783 1.00 67.22  ? 172  VAL D C   1 
ATOM   1241 O O   . VAL A 1 172 ? 236.046 237.068 123.838 1.00 67.22  ? 172  VAL D O   1 
ATOM   1242 C CB  . VAL A 1 172 ? 236.184 239.554 125.938 1.00 67.22  ? 172  VAL D CB  1 
ATOM   1243 C CG1 . VAL A 1 172 ? 236.056 238.271 126.745 1.00 67.22  ? 172  VAL D CG1 1 
ATOM   1244 C CG2 . VAL A 1 172 ? 237.088 240.545 126.650 1.00 67.22  ? 172  VAL D CG2 1 
ATOM   1245 N N   . GLY A 1 173 ? 234.812 238.785 123.078 1.00 66.68  ? 173  GLY D N   1 
ATOM   1246 C CA  . GLY A 1 173 ? 233.895 237.899 122.382 1.00 66.68  ? 173  GLY D CA  1 
ATOM   1247 C C   . GLY A 1 173 ? 234.556 237.119 121.261 1.00 66.68  ? 173  GLY D C   1 
ATOM   1248 O O   . GLY A 1 173 ? 234.308 235.921 121.099 1.00 66.68  ? 173  GLY D O   1 
ATOM   1249 N N   . LYS A 1 174 ? 235.408 237.781 120.475 1.00 67.24  ? 174  LYS D N   1 
ATOM   1250 C CA  . LYS A 1 174 ? 236.048 237.103 119.352 1.00 67.24  ? 174  LYS D CA  1 
ATOM   1251 C C   . LYS A 1 174 ? 237.046 236.051 119.817 1.00 67.24  ? 174  LYS D C   1 
ATOM   1252 O O   . LYS A 1 174 ? 237.292 235.075 119.100 1.00 67.24  ? 174  LYS D O   1 
ATOM   1253 C CB  . LYS A 1 174 ? 236.740 238.118 118.442 1.00 67.24  ? 174  LYS D CB  1 
ATOM   1254 C CG  . LYS A 1 174 ? 235.810 239.148 117.827 1.00 67.24  ? 174  LYS D CG  1 
ATOM   1255 C CD  . LYS A 1 174 ? 236.451 239.813 116.618 1.00 67.24  ? 174  LYS D CD  1 
ATOM   1256 C CE  . LYS A 1 174 ? 237.795 240.430 116.968 1.00 67.24  ? 174  LYS D CE  1 
ATOM   1257 N NZ  . LYS A 1 174 ? 237.668 241.509 117.984 1.00 67.24  ? 174  LYS D NZ  1 
ATOM   1258 N N   . GLN A 1 175 ? 237.628 236.228 121.005 1.00 67.55  ? 175  GLN D N   1 
ATOM   1259 C CA  . GLN A 1 175 ? 238.613 235.267 121.490 1.00 67.55  ? 175  GLN D CA  1 
ATOM   1260 C C   . GLN A 1 175 ? 237.958 233.975 121.962 1.00 67.55  ? 175  GLN D C   1 
ATOM   1261 O O   . GLN A 1 175 ? 238.593 232.915 121.930 1.00 67.55  ? 175  GLN D O   1 
ATOM   1262 C CB  . GLN A 1 175 ? 239.437 235.884 122.620 1.00 67.55  ? 175  GLN D CB  1 
ATOM   1263 C CG  . GLN A 1 175 ? 240.206 237.131 122.219 1.00 67.55  ? 175  GLN D CG  1 
ATOM   1264 C CD  . GLN A 1 175 ? 241.014 237.707 123.364 1.00 67.55  ? 175  GLN D CD  1 
ATOM   1265 O OE1 . GLN A 1 175 ? 240.991 237.186 124.479 1.00 67.55  ? 175  GLN D OE1 1 
ATOM   1266 N NE2 . GLN A 1 175 ? 241.735 238.789 123.094 1.00 67.55  ? 175  GLN D NE2 1 
ATOM   1267 N N   . LEU A 1 176 ? 236.703 234.039 122.397 1.00 64.52  ? 176  LEU D N   1 
ATOM   1268 C CA  . LEU A 1 176 ? 236.006 232.879 122.934 1.00 64.52  ? 176  LEU D CA  1 
ATOM   1269 C C   . LEU A 1 176 ? 235.196 232.125 121.886 1.00 64.52  ? 176  LEU D C   1 
ATOM   1270 O O   . LEU A 1 176 ? 234.371 231.284 122.254 1.00 64.52  ? 176  LEU D O   1 
ATOM   1271 C CB  . LEU A 1 176 ? 235.086 233.305 124.082 1.00 64.52  ? 176  LEU D CB  1 
ATOM   1272 C CG  . LEU A 1 176 ? 235.770 233.933 125.297 1.00 64.52  ? 176  LEU D CG  1 
ATOM   1273 C CD1 . LEU A 1 176 ? 234.744 234.337 126.342 1.00 64.52  ? 176  LEU D CD1 1 
ATOM   1274 C CD2 . LEU A 1 176 ? 236.792 232.976 125.888 1.00 64.52  ? 176  LEU D CD2 1 
ATOM   1275 N N   . ARG A 1 177 ? 235.409 232.400 120.592 1.00 66.90  ? 177  ARG D N   1 
ATOM   1276 C CA  . ARG A 1 177 ? 234.635 231.702 119.564 1.00 66.90  ? 177  ARG D CA  1 
ATOM   1277 C C   . ARG A 1 177 ? 235.100 230.260 119.389 1.00 66.90  ? 177  ARG D C   1 
ATOM   1278 O O   . ARG A 1 177 ? 234.277 229.339 119.548 1.00 66.90  ? 177  ARG D O   1 
ATOM   1279 C CB  . ARG A 1 177 ? 234.667 232.497 118.256 1.00 66.90  ? 177  ARG D CB  1 
ATOM   1280 C CG  . ARG A 1 177 ? 233.797 231.932 117.146 1.00 66.90  ? 177  ARG D CG  1 
ATOM   1281 C CD  . ARG A 1 177 ? 232.322 232.122 117.449 1.00 66.90  ? 177  ARG D CD  1 
ATOM   1282 N NE  . ARG A 1 177 ? 231.508 232.056 116.239 1.00 66.90  ? 177  ARG D NE  1 
ATOM   1283 C CZ  . ARG A 1 177 ? 230.906 230.957 115.800 1.00 66.90  ? 177  ARG D CZ  1 
ATOM   1284 N NH1 . ARG A 1 177 ? 230.186 230.993 114.687 1.00 66.90  ? 177  ARG D NH1 1 
ATOM   1285 N NH2 . ARG A 1 177 ? 231.021 229.822 116.472 1.00 66.90  ? 177  ARG D NH2 1 
ATOM   1286 N N   . PRO A 1 178 ? 236.374 229.978 119.079 1.00 66.61  ? 178  PRO D N   1 
ATOM   1287 C CA  . PRO A 1 178 ? 236.774 228.569 118.940 1.00 66.61  ? 178  PRO D CA  1 
ATOM   1288 C C   . PRO A 1 178 ? 236.761 227.821 120.258 1.00 66.61  ? 178  PRO D C   1 
ATOM   1289 O O   . PRO A 1 178 ? 236.471 226.617 120.275 1.00 66.61  ? 178  PRO D O   1 
ATOM   1290 C CB  . PRO A 1 178 ? 238.194 228.654 118.356 1.00 66.61  ? 178  PRO D CB  1 
ATOM   1291 C CG  . PRO A 1 178 ? 238.365 230.079 117.916 1.00 66.61  ? 178  PRO D CG  1 
ATOM   1292 C CD  . PRO A 1 178 ? 237.519 230.875 118.848 1.00 66.61  ? 178  PRO D CD  1 
ATOM   1293 N N   . LEU A 1 179 ? 237.068 228.502 121.365 1.00 63.70  ? 179  LEU D N   1 
ATOM   1294 C CA  . LEU A 1 179 ? 236.981 227.864 122.673 1.00 63.70  ? 179  LEU D CA  1 
ATOM   1295 C C   . LEU A 1 179 ? 235.568 227.369 122.945 1.00 63.70  ? 179  LEU D C   1 
ATOM   1296 O O   . LEU A 1 179 ? 235.378 226.235 123.396 1.00 63.70  ? 179  LEU D O   1 
ATOM   1297 C CB  . LEU A 1 179 ? 237.433 228.832 123.768 1.00 63.70  ? 179  LEU D CB  1 
ATOM   1298 C CG  . LEU A 1 179 ? 238.940 229.029 123.962 1.00 63.70  ? 179  LEU D CG  1 
ATOM   1299 C CD1 . LEU A 1 179 ? 239.651 227.685 124.036 1.00 63.70  ? 179  LEU D CD1 1 
ATOM   1300 C CD2 . LEU A 1 179 ? 239.546 229.907 122.874 1.00 63.70  ? 179  LEU D CD2 1 
ATOM   1301 N N   . TYR A 1 180 ? 234.560 228.194 122.653 1.00 62.60  ? 180  TYR D N   1 
ATOM   1302 C CA  . TYR A 1 180 ? 233.179 227.767 122.852 1.00 62.60  ? 180  TYR D CA  1 
ATOM   1303 C C   . TYR A 1 180 ? 232.767 226.709 121.835 1.00 62.60  ? 180  TYR D C   1 
ATOM   1304 O O   . TYR A 1 180 ? 231.988 225.805 122.165 1.00 62.60  ? 180  TYR D O   1 
ATOM   1305 C CB  . TYR A 1 180 ? 232.243 228.973 122.782 1.00 62.60  ? 180  TYR D CB  1 
ATOM   1306 C CG  . TYR A 1 180 ? 230.906 228.760 123.455 1.00 62.60  ? 180  TYR D CG  1 
ATOM   1307 C CD1 . TYR A 1 180 ? 230.788 228.812 124.837 1.00 62.60  ? 180  TYR D CD1 1 
ATOM   1308 C CD2 . TYR A 1 180 ? 229.760 228.519 122.709 1.00 62.60  ? 180  TYR D CD2 1 
ATOM   1309 C CE1 . TYR A 1 180 ? 229.569 228.621 125.459 1.00 62.60  ? 180  TYR D CE1 1 
ATOM   1310 C CE2 . TYR A 1 180 ? 228.536 228.328 123.321 1.00 62.60  ? 180  TYR D CE2 1 
ATOM   1311 C CZ  . TYR A 1 180 ? 228.447 228.379 124.696 1.00 62.60  ? 180  TYR D CZ  1 
ATOM   1312 O OH  . TYR A 1 180 ? 227.231 228.189 125.310 1.00 62.60  ? 180  TYR D OH  1 
ATOM   1313 N N   . GLU A 1 181 ? 233.278 226.799 120.602 1.00 64.10  ? 181  GLU D N   1 
ATOM   1314 C CA  . GLU A 1 181 ? 232.964 225.787 119.597 1.00 64.10  ? 181  GLU D CA  1 
ATOM   1315 C C   . GLU A 1 181 ? 233.482 224.415 120.011 1.00 64.10  ? 181  GLU D C   1 
ATOM   1316 O O   . GLU A 1 181 ? 232.850 223.392 119.723 1.00 64.10  ? 181  GLU D O   1 
ATOM   1317 C CB  . GLU A 1 181 ? 233.546 226.187 118.242 1.00 64.10  ? 181  GLU D CB  1 
ATOM   1318 C CG  . GLU A 1 181 ? 232.789 227.297 117.541 1.00 64.10  ? 181  GLU D CG  1 
ATOM   1319 C CD  . GLU A 1 181 ? 233.337 227.590 116.159 1.00 64.10  ? 181  GLU D CD  1 
ATOM   1320 O OE1 . GLU A 1 181 ? 234.349 226.968 115.775 1.00 64.10  ? 181  GLU D OE1 1 
ATOM   1321 O OE2 . GLU A 1 181 ? 232.755 228.442 115.455 1.00 64.10  ? 181  GLU D OE2 1 
ATOM   1322 N N   . GLU A 1 182 ? 234.638 224.369 120.672 1.00 64.63  ? 182  GLU D N   1 
ATOM   1323 C CA  . GLU A 1 182 ? 235.135 223.097 121.185 1.00 64.63  ? 182  GLU D CA  1 
ATOM   1324 C C   . GLU A 1 182 ? 234.447 222.701 122.486 1.00 64.63  ? 182  GLU D C   1 
ATOM   1325 O O   . GLU A 1 182 ? 234.245 221.507 122.741 1.00 64.63  ? 182  GLU D O   1 
ATOM   1326 C CB  . GLU A 1 182 ? 236.649 223.163 121.389 1.00 64.63  ? 182  GLU D CB  1 
ATOM   1327 C CG  . GLU A 1 182 ? 237.440 223.382 120.111 1.00 64.63  ? 182  GLU D CG  1 
ATOM   1328 C CD  . GLU A 1 182 ? 238.938 223.299 120.333 1.00 64.63  ? 182  GLU D CD  1 
ATOM   1329 O OE1 . GLU A 1 182 ? 239.355 222.970 121.463 1.00 64.63  ? 182  GLU D OE1 1 
ATOM   1330 O OE2 . GLU A 1 182 ? 239.697 223.561 119.377 1.00 64.63  ? 182  GLU D OE2 1 
ATOM   1331 N N   . TYR A 1 183 ? 234.079 223.688 123.308 1.00 61.55  ? 183  TYR D N   1 
ATOM   1332 C CA  . TYR A 1 183 ? 233.412 223.412 124.574 1.00 61.55  ? 183  TYR D CA  1 
ATOM   1333 C C   . TYR A 1 183 ? 232.061 222.747 124.355 1.00 61.55  ? 183  TYR D C   1 
ATOM   1334 O O   . TYR A 1 183 ? 231.708 221.799 125.065 1.00 61.55  ? 183  TYR D O   1 
ATOM   1335 C CB  . TYR A 1 183 ? 233.260 224.715 125.362 1.00 61.55  ? 183  TYR D CB  1 
ATOM   1336 C CG  . TYR A 1 183 ? 232.255 224.671 126.491 1.00 61.55  ? 183  TYR D CG  1 
ATOM   1337 C CD1 . TYR A 1 183 ? 232.610 224.196 127.746 1.00 61.55  ? 183  TYR D CD1 1 
ATOM   1338 C CD2 . TYR A 1 183 ? 230.956 225.129 126.309 1.00 61.55  ? 183  TYR D CD2 1 
ATOM   1339 C CE1 . TYR A 1 183 ? 231.696 224.164 128.781 1.00 61.55  ? 183  TYR D CE1 1 
ATOM   1340 C CE2 . TYR A 1 183 ? 230.036 225.099 127.337 1.00 61.55  ? 183  TYR D CE2 1 
ATOM   1341 C CZ  . TYR A 1 183 ? 230.411 224.616 128.571 1.00 61.55  ? 183  TYR D CZ  1 
ATOM   1342 O OH  . TYR A 1 183 ? 229.498 224.586 129.599 1.00 61.55  ? 183  TYR D OH  1 
ATOM   1343 N N   . VAL A 1 184 ? 231.289 223.230 123.379 1.00 61.41  ? 184  VAL D N   1 
ATOM   1344 C CA  . VAL A 1 184 ? 229.975 222.643 123.134 1.00 61.41  ? 184  VAL D CA  1 
ATOM   1345 C C   . VAL A 1 184 ? 230.113 221.200 122.660 1.00 61.41  ? 184  VAL D C   1 
ATOM   1346 O O   . VAL A 1 184 ? 229.346 220.324 123.074 1.00 61.41  ? 184  VAL D O   1 
ATOM   1347 C CB  . VAL A 1 184 ? 229.167 223.502 122.141 1.00 61.41  ? 184  VAL D CB  1 
ATOM   1348 C CG1 . VAL A 1 184 ? 228.851 224.855 122.752 1.00 61.41  ? 184  VAL D CG1 1 
ATOM   1349 C CG2 . VAL A 1 184 ? 229.911 223.674 120.829 1.00 61.41  ? 184  VAL D CG2 1 
ATOM   1350 N N   . VAL A 1 185 ? 231.112 220.921 121.819 1.00 59.98  ? 185  VAL D N   1 
ATOM   1351 C CA  . VAL A 1 185 ? 231.310 219.560 121.328 1.00 59.98  ? 185  VAL D CA  1 
ATOM   1352 C C   . VAL A 1 185 ? 231.735 218.636 122.463 1.00 59.98  ? 185  VAL D C   1 
ATOM   1353 O O   . VAL A 1 185 ? 231.227 217.514 122.593 1.00 59.98  ? 185  VAL D O   1 
ATOM   1354 C CB  . VAL A 1 185 ? 232.331 219.551 120.176 1.00 59.98  ? 185  VAL D CB  1 
ATOM   1355 C CG1 . VAL A 1 185 ? 232.611 218.127 119.724 1.00 59.98  ? 185  VAL D CG1 1 
ATOM   1356 C CG2 . VAL A 1 185 ? 231.824 220.390 119.015 1.00 59.98  ? 185  VAL D CG2 1 
ATOM   1357 N N   . LEU A 1 186 ? 232.669 219.090 123.304 1.00 60.61  ? 186  LEU D N   1 
ATOM   1358 C CA  . LEU A 1 186 ? 233.119 218.257 124.415 1.00 60.61  ? 186  LEU D CA  1 
ATOM   1359 C C   . LEU A 1 186 ? 231.993 218.004 125.410 1.00 60.61  ? 186  LEU D C   1 
ATOM   1360 O O   . LEU A 1 186 ? 231.849 216.888 125.926 1.00 60.61  ? 186  LEU D O   1 
ATOM   1361 C CB  . LEU A 1 186 ? 234.318 218.906 125.106 1.00 60.61  ? 186  LEU D CB  1 
ATOM   1362 C CG  . LEU A 1 186 ? 235.593 218.991 124.264 1.00 60.61  ? 186  LEU D CG  1 
ATOM   1363 C CD1 . LEU A 1 186 ? 236.709 219.673 125.037 1.00 60.61  ? 186  LEU D CD1 1 
ATOM   1364 C CD2 . LEU A 1 186 ? 236.023 217.608 123.802 1.00 60.61  ? 186  LEU D CD2 1 
ATOM   1365 N N   . LYS A 1 187 ? 231.168 219.020 125.678 1.00 58.82  ? 187  LYS D N   1 
ATOM   1366 C CA  . LYS A 1 187 ? 230.054 218.837 126.601 1.00 58.82  ? 187  LYS D CA  1 
ATOM   1367 C C   . LYS A 1 187 ? 228.992 217.917 126.013 1.00 58.82  ? 187  LYS D C   1 
ATOM   1368 O O   . LYS A 1 187 ? 228.391 217.116 126.738 1.00 58.82  ? 187  LYS D O   1 
ATOM   1369 C CB  . LYS A 1 187 ? 229.451 220.191 126.973 1.00 58.82  ? 187  LYS D CB  1 
ATOM   1370 C CG  . LYS A 1 187 ? 230.288 220.982 127.963 1.00 58.82  ? 187  LYS D CG  1 
ATOM   1371 C CD  . LYS A 1 187 ? 230.477 220.206 129.257 1.00 58.82  ? 187  LYS D CD  1 
ATOM   1372 C CE  . LYS A 1 187 ? 231.280 221.002 130.271 1.00 58.82  ? 187  LYS D CE  1 
ATOM   1373 N NZ  . LYS A 1 187 ? 231.434 220.270 131.557 1.00 58.82  ? 187  LYS D NZ  1 
ATOM   1374 N N   . ASN A 1 188 ? 228.750 218.005 124.702 1.00 61.58  ? 188  ASN D N   1 
ATOM   1375 C CA  . ASN A 1 188 ? 227.810 217.087 124.069 1.00 61.58  ? 188  ASN D CA  1 
ATOM   1376 C C   . ASN A 1 188 ? 228.316 215.653 124.134 1.00 61.58  ? 188  ASN D C   1 
ATOM   1377 O O   . ASN A 1 188 ? 227.539 214.724 124.382 1.00 61.58  ? 188  ASN D O   1 
ATOM   1378 C CB  . ASN A 1 188 ? 227.557 217.505 122.621 1.00 61.58  ? 188  ASN D CB  1 
ATOM   1379 C CG  . ASN A 1 188 ? 226.746 218.780 122.516 1.00 61.58  ? 188  ASN D CG  1 
ATOM   1380 O OD1 . ASN A 1 188 ? 225.941 219.091 123.394 1.00 61.58  ? 188  ASN D OD1 1 
ATOM   1381 N ND2 . ASN A 1 188 ? 226.952 219.526 121.437 1.00 61.58  ? 188  ASN D ND2 1 
ATOM   1382 N N   . GLU A 1 189 ? 229.619 215.452 123.917 1.00 64.06  ? 189  GLU D N   1 
ATOM   1383 C CA  . GLU A 1 189 ? 230.182 214.110 124.038 1.00 64.06  ? 189  GLU D CA  1 
ATOM   1384 C C   . GLU A 1 189 ? 230.061 213.589 125.465 1.00 64.06  ? 189  GLU D C   1 
ATOM   1385 O O   . GLU A 1 189 ? 229.698 212.425 125.680 1.00 64.06  ? 189  GLU D O   1 
ATOM   1386 C CB  . GLU A 1 189 ? 231.642 214.107 123.586 1.00 64.06  ? 189  GLU D CB  1 
ATOM   1387 C CG  . GLU A 1 189 ? 231.833 214.352 122.099 1.00 64.06  ? 189  GLU D CG  1 
ATOM   1388 C CD  . GLU A 1 189 ? 233.285 214.259 121.677 1.00 64.06  ? 189  GLU D CD  1 
ATOM   1389 O OE1 . GLU A 1 189 ? 234.139 213.967 122.540 1.00 64.06  ? 189  GLU D OE1 1 
ATOM   1390 O OE2 . GLU A 1 189 ? 233.573 214.477 120.481 1.00 64.06  ? 189  GLU D OE2 1 
ATOM   1391 N N   . MET A 1 190 ? 230.355 214.438 126.453 1.00 62.33  ? 190  MET D N   1 
ATOM   1392 C CA  . MET A 1 190 ? 230.224 214.027 127.847 1.00 62.33  ? 190  MET D CA  1 
ATOM   1393 C C   . MET A 1 190 ? 228.782 213.668 128.186 1.00 62.33  ? 190  MET D C   1 
ATOM   1394 O O   . MET A 1 190 ? 228.528 212.687 128.895 1.00 62.33  ? 190  MET D O   1 
ATOM   1395 C CB  . MET A 1 190 ? 230.732 215.134 128.771 1.00 62.33  ? 190  MET D CB  1 
ATOM   1396 C CG  . MET A 1 190 ? 230.471 214.877 130.246 1.00 62.33  ? 190  MET D CG  1 
ATOM   1397 S SD  . MET A 1 190 ? 231.114 216.181 131.310 1.00 62.33  ? 190  MET D SD  1 
ATOM   1398 C CE  . MET A 1 190 ? 232.868 216.042 130.983 1.00 62.33  ? 190  MET D CE  1 
ATOM   1399 N N   . ALA A 1 191 ? 227.822 214.449 127.684 1.00 60.69  ? 191  ALA D N   1 
ATOM   1400 C CA  . ALA A 1 191 ? 226.419 214.173 127.972 1.00 60.69  ? 191  ALA D CA  1 
ATOM   1401 C C   . ALA A 1 191 ? 225.959 212.886 127.301 1.00 60.69  ? 191  ALA D C   1 
ATOM   1402 O O   . ALA A 1 191 ? 225.231 212.091 127.907 1.00 60.69  ? 191  ALA D O   1 
ATOM   1403 C CB  . ALA A 1 191 ? 225.552 215.350 127.532 1.00 60.69  ? 191  ALA D CB  1 
ATOM   1404 N N   . ARG A 1 192 ? 226.372 212.659 126.051 1.00 61.59  ? 192  ARG D N   1 
ATOM   1405 C CA  . ARG A 1 192 ? 226.015 211.416 125.378 1.00 61.59  ? 192  ARG D CA  1 
ATOM   1406 C C   . ARG A 1 192 ? 226.675 210.213 126.039 1.00 61.59  ? 192  ARG D C   1 
ATOM   1407 O O   . ARG A 1 192 ? 226.139 209.101 125.975 1.00 61.59  ? 192  ARG D O   1 
ATOM   1408 C CB  . ARG A 1 192 ? 226.395 211.485 123.899 1.00 61.59  ? 192  ARG D CB  1 
ATOM   1409 C CG  . ARG A 1 192 ? 225.583 212.486 123.095 1.00 61.59  ? 192  ARG D CG  1 
ATOM   1410 C CD  . ARG A 1 192 ? 225.869 212.358 121.609 1.00 61.59  ? 192  ARG D CD  1 
ATOM   1411 N NE  . ARG A 1 192 ? 225.093 213.308 120.819 1.00 61.59  ? 192  ARG D NE  1 
ATOM   1412 C CZ  . ARG A 1 192 ? 225.544 214.495 120.426 1.00 61.59  ? 192  ARG D CZ  1 
ATOM   1413 N NH1 . ARG A 1 192 ? 224.769 215.297 119.709 1.00 61.59  ? 192  ARG D NH1 1 
ATOM   1414 N NH2 . ARG A 1 192 ? 226.772 214.878 120.746 1.00 61.59  ? 192  ARG D NH2 1 
ATOM   1415 N N   . ALA A 1 193 ? 227.831 210.413 126.676 1.00 62.25  ? 193  ALA D N   1 
ATOM   1416 C CA  . ALA A 1 193 ? 228.454 209.322 127.417 1.00 62.25  ? 193  ALA D CA  1 
ATOM   1417 C C   . ALA A 1 193 ? 227.698 209.016 128.704 1.00 62.25  ? 193  ALA D C   1 
ATOM   1418 O O   . ALA A 1 193 ? 227.719 207.873 129.175 1.00 62.25  ? 193  ALA D O   1 
ATOM   1419 C CB  . ALA A 1 193 ? 229.913 209.657 127.721 1.00 62.25  ? 193  ALA D CB  1 
ATOM   1420 N N   . ASN A 1 194 ? 227.029 210.013 129.283 1.00 62.61  ? 194  ASN D N   1 
ATOM   1421 C CA  . ASN A 1 194 ? 226.236 209.834 130.491 1.00 62.61  ? 194  ASN D CA  1 
ATOM   1422 C C   . ASN A 1 194 ? 224.789 209.455 130.195 1.00 62.61  ? 194  ASN D C   1 
ATOM   1423 O O   . ASN A 1 194 ? 223.920 209.656 131.052 1.00 62.61  ? 194  ASN D O   1 
ATOM   1424 C CB  . ASN A 1 194 ? 226.278 211.103 131.346 1.00 62.61  ? 194  ASN D CB  1 
ATOM   1425 C CG  . ASN A 1 194 ? 227.661 211.394 131.891 1.00 62.61  ? 194  ASN D CG  1 
ATOM   1426 O OD1 . ASN A 1 194 ? 228.061 210.850 132.920 1.00 62.61  ? 194  ASN D OD1 1 
ATOM   1427 N ND2 . ASN A 1 194 ? 228.397 212.260 131.205 1.00 62.61  ? 194  ASN D ND2 1 
ATOM   1428 N N   . HIS A 1 195 ? 224.516 208.922 129.002 1.00 62.68  ? 195  HIS D N   1 
ATOM   1429 C CA  . HIS A 1 195 ? 223.176 208.481 128.606 1.00 62.68  ? 195  HIS D CA  1 
ATOM   1430 C C   . HIS A 1 195 ? 222.190 209.649 128.579 1.00 62.68  ? 195  HIS D C   1 
ATOM   1431 O O   . HIS A 1 195 ? 221.066 209.559 129.078 1.00 62.68  ? 195  HIS D O   1 
ATOM   1432 C CB  . HIS A 1 195 ? 222.674 207.355 129.514 1.00 62.68  ? 195  HIS D CB  1 
ATOM   1433 C CG  . HIS A 1 195 ? 223.568 206.154 129.540 1.00 62.68  ? 195  HIS D CG  1 
ATOM   1434 N ND1 . HIS A 1 195 ? 223.447 205.156 130.482 1.00 62.68  ? 195  HIS D ND1 1 
ATOM   1435 C CD2 . HIS A 1 195 ? 224.597 205.791 128.737 1.00 62.68  ? 195  HIS D CD2 1 
ATOM   1436 C CE1 . HIS A 1 195 ? 224.363 204.230 130.260 1.00 62.68  ? 195  HIS D CE1 1 
ATOM   1437 N NE2 . HIS A 1 195 ? 225.074 204.592 129.207 1.00 62.68  ? 195  HIS D NE2 1 
ATOM   1438 N N   . TYR A 1 196 ? 222.623 210.757 127.985 1.00 60.02  ? 196  TYR D N   1 
ATOM   1439 C CA  . TYR A 1 196 ? 221.780 211.921 127.761 1.00 60.02  ? 196  TYR D CA  1 
ATOM   1440 C C   . TYR A 1 196 ? 221.759 212.258 126.275 1.00 60.02  ? 196  TYR D C   1 
ATOM   1441 O O   . TYR A 1 196 ? 222.577 211.772 125.490 1.00 60.02  ? 196  TYR D O   1 
ATOM   1442 C CB  . TYR A 1 196 ? 222.265 213.131 128.571 1.00 60.02  ? 196  TYR D CB  1 
ATOM   1443 C CG  . TYR A 1 196 ? 221.991 213.039 130.055 1.00 60.02  ? 196  TYR D CG  1 
ATOM   1444 C CD1 . TYR A 1 196 ? 222.974 212.614 130.938 1.00 60.02  ? 196  TYR D CD1 1 
ATOM   1445 C CD2 . TYR A 1 196 ? 220.751 213.383 130.574 1.00 60.02  ? 196  TYR D CD2 1 
ATOM   1446 C CE1 . TYR A 1 196 ? 222.728 212.531 132.296 1.00 60.02  ? 196  TYR D CE1 1 
ATOM   1447 C CE2 . TYR A 1 196 ? 220.495 213.304 131.929 1.00 60.02  ? 196  TYR D CE2 1 
ATOM   1448 C CZ  . TYR A 1 196 ? 221.487 212.877 132.785 1.00 60.02  ? 196  TYR D CZ  1 
ATOM   1449 O OH  . TYR A 1 196 ? 221.237 212.796 134.136 1.00 60.02  ? 196  TYR D OH  1 
ATOM   1450 N N   . GLU A 1 197 ? 220.803 213.106 125.893 1.00 62.57  ? 197  GLU D N   1 
ATOM   1451 C CA  . GLU A 1 197 ? 220.699 213.522 124.498 1.00 62.57  ? 197  GLU D CA  1 
ATOM   1452 C C   . GLU A 1 197 ? 221.703 214.618 124.166 1.00 62.57  ? 197  GLU D C   1 
ATOM   1453 O O   . GLU A 1 197 ? 222.364 214.563 123.123 1.00 62.57  ? 197  GLU D O   1 
ATOM   1454 C CB  . GLU A 1 197 ? 219.276 213.992 124.195 1.00 62.57  ? 197  GLU D CB  1 
ATOM   1455 C CG  . GLU A 1 197 ? 218.212 212.930 124.413 1.00 62.57  ? 197  GLU D CG  1 
ATOM   1456 C CD  . GLU A 1 197 ? 216.818 213.428 124.090 1.00 62.57  ? 197  GLU D CD  1 
ATOM   1457 O OE1 . GLU A 1 197 ? 216.683 214.605 123.694 1.00 62.57  ? 197  GLU D OE1 1 
ATOM   1458 O OE2 . GLU A 1 197 ? 215.857 212.643 124.231 1.00 62.57  ? 197  GLU D OE2 1 
ATOM   1459 N N   . ASP A 1 198 ? 221.829 215.615 125.035 1.00 60.89  ? 198  ASP D N   1 
ATOM   1460 C CA  . ASP A 1 198 ? 222.774 216.707 124.841 1.00 60.89  ? 198  ASP D CA  1 
ATOM   1461 C C   . ASP A 1 198 ? 223.054 217.338 126.200 1.00 60.89  ? 198  ASP D C   1 
ATOM   1462 O O   . ASP A 1 198 ? 222.509 216.918 127.224 1.00 60.89  ? 198  ASP D O   1 
ATOM   1463 C CB  . ASP A 1 198 ? 222.238 217.731 123.836 1.00 60.89  ? 198  ASP D CB  1 
ATOM   1464 C CG  . ASP A 1 198 ? 220.830 218.186 124.161 1.00 60.89  ? 198  ASP D CG  1 
ATOM   1465 O OD1 . ASP A 1 198 ? 220.657 218.952 125.131 1.00 60.89  ? 198  ASP D OD1 1 
ATOM   1466 O OD2 . ASP A 1 198 ? 219.892 217.776 123.444 1.00 60.89  ? 198  ASP D OD2 1 
ATOM   1467 N N   . TYR A 1 199 ? 223.919 218.355 126.202 1.00 57.25  ? 199  TYR D N   1 
ATOM   1468 C CA  . TYR A 1 199 ? 224.276 219.008 127.457 1.00 57.25  ? 199  TYR D CA  1 
ATOM   1469 C C   . TYR A 1 199 ? 223.105 219.796 128.031 1.00 57.25  ? 199  TYR D C   1 
ATOM   1470 O O   . TYR A 1 199 ? 222.979 219.914 129.256 1.00 57.25  ? 199  TYR D O   1 
ATOM   1471 C CB  . TYR A 1 199 ? 225.488 219.915 127.251 1.00 57.25  ? 199  TYR D CB  1 
ATOM   1472 C CG  . TYR A 1 199 ? 226.160 220.334 128.538 1.00 57.25  ? 199  TYR D CG  1 
ATOM   1473 C CD1 . TYR A 1 199 ? 226.591 219.387 129.457 1.00 57.25  ? 199  TYR D CD1 1 
ATOM   1474 C CD2 . TYR A 1 199 ? 226.376 221.674 128.828 1.00 57.25  ? 199  TYR D CD2 1 
ATOM   1475 C CE1 . TYR A 1 199 ? 227.208 219.763 130.634 1.00 57.25  ? 199  TYR D CE1 1 
ATOM   1476 C CE2 . TYR A 1 199 ? 226.994 222.059 130.001 1.00 57.25  ? 199  TYR D CE2 1 
ATOM   1477 C CZ  . TYR A 1 199 ? 227.408 221.100 130.900 1.00 57.25  ? 199  TYR D CZ  1 
ATOM   1478 O OH  . TYR A 1 199 ? 228.024 221.479 132.071 1.00 57.25  ? 199  TYR D OH  1 
ATOM   1479 N N   . GLY A 1 200 ? 222.242 220.338 127.170 1.00 56.76  ? 200  GLY D N   1 
ATOM   1480 C CA  . GLY A 1 200 ? 221.026 220.964 127.660 1.00 56.76  ? 200  GLY D CA  1 
ATOM   1481 C C   . GLY A 1 200 ? 220.120 219.977 128.370 1.00 56.76  ? 200  GLY D C   1 
ATOM   1482 O O   . GLY A 1 200 ? 219.482 220.311 129.370 1.00 56.76  ? 200  GLY D O   1 
ATOM   1483 N N   . ASP A 1 201 ? 220.064 218.741 127.870 1.00 56.63  ? 201  ASP D N   1 
ATOM   1484 C CA  . ASP A 1 201 ? 219.308 217.699 128.555 1.00 56.63  ? 201  ASP D CA  1 
ATOM   1485 C C   . ASP A 1 201 ? 219.941 217.362 129.900 1.00 56.63  ? 201  ASP D C   1 
ATOM   1486 O O   . ASP A 1 201 ? 219.233 217.140 130.890 1.00 56.63  ? 201  ASP D O   1 
ATOM   1487 C CB  . ASP A 1 201 ? 219.219 216.456 127.671 1.00 56.63  ? 201  ASP D CB  1 
ATOM   1488 C CG  . ASP A 1 201 ? 218.108 215.519 128.091 1.00 56.63  ? 201  ASP D CG  1 
ATOM   1489 O OD1 . ASP A 1 201 ? 216.930 215.842 127.832 1.00 56.63  ? 201  ASP D OD1 1 
ATOM   1490 O OD2 . ASP A 1 201 ? 218.411 214.458 128.676 1.00 56.63  ? 201  ASP D OD2 1 
ATOM   1491 N N   . TYR A 1 202 ? 221.275 217.333 129.957 1.00 58.01  ? 202  TYR D N   1 
ATOM   1492 C CA  . TYR A 1 202 ? 221.962 217.097 131.223 1.00 58.01  ? 202  TYR D CA  1 
ATOM   1493 C C   . TYR A 1 202 ? 221.661 218.203 132.227 1.00 58.01  ? 202  TYR D C   1 
ATOM   1494 O O   . TYR A 1 202 ? 221.536 217.943 133.429 1.00 58.01  ? 202  TYR D O   1 
ATOM   1495 C CB  . TYR A 1 202 ? 223.468 216.980 130.983 1.00 58.01  ? 202  TYR D CB  1 
ATOM   1496 C CG  . TYR A 1 202 ? 224.290 216.804 132.241 1.00 58.01  ? 202  TYR D CG  1 
ATOM   1497 C CD1 . TYR A 1 202 ? 224.901 217.890 132.853 1.00 58.01  ? 202  TYR D CD1 1 
ATOM   1498 C CD2 . TYR A 1 202 ? 224.460 215.550 132.812 1.00 58.01  ? 202  TYR D CD2 1 
ATOM   1499 C CE1 . TYR A 1 202 ? 225.655 217.734 134.000 1.00 58.01  ? 202  TYR D CE1 1 
ATOM   1500 C CE2 . TYR A 1 202 ? 225.212 215.384 133.959 1.00 58.01  ? 202  TYR D CE2 1 
ATOM   1501 C CZ  . TYR A 1 202 ? 225.807 216.480 134.549 1.00 58.01  ? 202  TYR D CZ  1 
ATOM   1502 O OH  . TYR A 1 202 ? 226.556 216.320 135.691 1.00 58.01  ? 202  TYR D OH  1 
ATOM   1503 N N   . TRP A 1 203 ? 221.544 219.444 131.752 1.00 56.83  ? 203  TRP D N   1 
ATOM   1504 C CA  . TRP A 1 203 ? 221.207 220.546 132.648 1.00 56.83  ? 203  TRP D CA  1 
ATOM   1505 C C   . TRP A 1 203 ? 219.752 220.472 133.098 1.00 56.83  ? 203  TRP D C   1 
ATOM   1506 O O   . TRP A 1 203 ? 219.446 220.727 134.269 1.00 56.83  ? 203  TRP D O   1 
ATOM   1507 C CB  . TRP A 1 203 ? 221.492 221.883 131.968 1.00 56.83  ? 203  TRP D CB  1 
ATOM   1508 C CG  . TRP A 1 203 ? 222.848 222.427 132.282 1.00 56.83  ? 203  TRP D CG  1 
ATOM   1509 C CD1 . TRP A 1 203 ? 223.689 222.009 133.271 1.00 56.83  ? 203  TRP D CD1 1 
ATOM   1510 C CD2 . TRP A 1 203 ? 223.523 223.490 131.602 1.00 56.83  ? 203  TRP D CD2 1 
ATOM   1511 N NE1 . TRP A 1 203 ? 224.846 222.748 133.251 1.00 56.83  ? 203  TRP D NE1 1 
ATOM   1512 C CE2 . TRP A 1 203 ? 224.770 223.663 132.235 1.00 56.83  ? 203  TRP D CE2 1 
ATOM   1513 C CE3 . TRP A 1 203 ? 223.196 224.312 130.520 1.00 56.83  ? 203  TRP D CE3 1 
ATOM   1514 C CZ2 . TRP A 1 203 ? 225.687 224.625 131.822 1.00 56.83  ? 203  TRP D CZ2 1 
ATOM   1515 C CZ3 . TRP A 1 203 ? 224.108 225.264 130.112 1.00 56.83  ? 203  TRP D CZ3 1 
ATOM   1516 C CH2 . TRP A 1 203 ? 225.339 225.412 130.761 1.00 56.83  ? 203  TRP D CH2 1 
ATOM   1517 N N   . ARG A 1 204 ? 218.841 220.129 132.184 1.00 54.92  ? 204  ARG D N   1 
ATOM   1518 C CA  . ARG A 1 204 ? 217.433 220.007 132.544 1.00 54.92  ? 204  ARG D CA  1 
ATOM   1519 C C   . ARG A 1 204 ? 217.167 218.806 133.441 1.00 54.92  ? 204  ARG D C   1 
ATOM   1520 O O   . ARG A 1 204 ? 216.123 218.764 134.102 1.00 54.92  ? 204  ARG D O   1 
ATOM   1521 C CB  . ARG A 1 204 ? 216.568 219.914 131.287 1.00 54.92  ? 204  ARG D CB  1 
ATOM   1522 C CG  . ARG A 1 204 ? 216.574 221.166 130.430 1.00 54.92  ? 204  ARG D CG  1 
ATOM   1523 C CD  . ARG A 1 204 ? 215.515 221.093 129.343 1.00 54.92  ? 204  ARG D CD  1 
ATOM   1524 N NE  . ARG A 1 204 ? 215.711 219.952 128.454 1.00 54.92  ? 204  ARG D NE  1 
ATOM   1525 C CZ  . ARG A 1 204 ? 216.377 220.005 127.306 1.00 54.92  ? 204  ARG D CZ  1 
ATOM   1526 N NH1 . ARG A 1 204 ? 216.505 218.916 126.560 1.00 54.92  ? 204  ARG D NH1 1 
ATOM   1527 N NH2 . ARG A 1 204 ? 216.914 221.147 126.901 1.00 54.92  ? 204  ARG D NH2 1 
ATOM   1528 N N   . GLY A 1 205 ? 218.078 217.831 133.472 1.00 55.56  ? 205  GLY D N   1 
ATOM   1529 C CA  . GLY A 1 205 ? 217.910 216.678 134.340 1.00 55.56  ? 205  GLY D CA  1 
ATOM   1530 C C   . GLY A 1 205 ? 217.798 217.014 135.814 1.00 55.56  ? 205  GLY D C   1 
ATOM   1531 O O   . GLY A 1 205 ? 217.355 216.169 136.600 1.00 55.56  ? 205  GLY D O   1 
ATOM   1532 N N   . ASP A 1 206 ? 218.192 218.227 136.211 1.00 55.27  ? 206  ASP D N   1 
ATOM   1533 C CA  . ASP A 1 206 ? 218.050 218.629 137.607 1.00 55.27  ? 206  ASP D CA  1 
ATOM   1534 C C   . ASP A 1 206 ? 216.586 218.762 138.006 1.00 55.27  ? 206  ASP D C   1 
ATOM   1535 O O   . ASP A 1 206 ? 216.251 218.628 139.188 1.00 55.27  ? 206  ASP D O   1 
ATOM   1536 C CB  . ASP A 1 206 ? 218.791 219.943 137.851 1.00 55.27  ? 206  ASP D CB  1 
ATOM   1537 C CG  . ASP A 1 206 ? 218.722 220.391 139.297 1.00 55.27  ? 206  ASP D CG  1 
ATOM   1538 O OD1 . ASP A 1 206 ? 219.356 219.740 140.154 1.00 55.27  ? 206  ASP D OD1 1 
ATOM   1539 O OD2 . ASP A 1 206 ? 218.034 221.395 139.578 1.00 55.27  ? 206  ASP D OD2 1 
ATOM   1540 N N   . TYR A 1 207 ? 215.705 219.020 137.043 1.00 54.24  ? 207  TYR D N   1 
ATOM   1541 C CA  . TYR A 1 207 ? 214.274 219.127 137.290 1.00 54.24  ? 207  TYR D CA  1 
ATOM   1542 C C   . TYR A 1 207 ? 213.542 217.808 137.087 1.00 54.24  ? 207  TYR D C   1 
ATOM   1543 O O   . TYR A 1 207 ? 212.312 217.775 137.195 1.00 54.24  ? 207  TYR D O   1 
ATOM   1544 C CB  . TYR A 1 207 ? 213.661 220.198 136.380 1.00 54.24  ? 207  TYR D CB  1 
ATOM   1545 C CG  . TYR A 1 207 ? 214.240 221.581 136.578 1.00 54.24  ? 207  TYR D CG  1 
ATOM   1546 C CD1 . TYR A 1 207 ? 215.445 221.942 135.990 1.00 54.24  ? 207  TYR D CD1 1 
ATOM   1547 C CD2 . TYR A 1 207 ? 213.577 222.529 137.346 1.00 54.24  ? 207  TYR D CD2 1 
ATOM   1548 C CE1 . TYR A 1 207 ? 215.977 223.203 136.166 1.00 54.24  ? 207  TYR D CE1 1 
ATOM   1549 C CE2 . TYR A 1 207 ? 214.102 223.793 137.527 1.00 54.24  ? 207  TYR D CE2 1 
ATOM   1550 C CZ  . TYR A 1 207 ? 215.302 224.124 136.935 1.00 54.24  ? 207  TYR D CZ  1 
ATOM   1551 O OH  . TYR A 1 207 ? 215.831 225.382 137.112 1.00 54.24  ? 207  TYR D OH  1 
ATOM   1552 N N   . GLU A 1 208 ? 214.264 216.728 136.799 1.00 57.02  ? 208  GLU D N   1 
ATOM   1553 C CA  . GLU A 1 208 ? 213.659 215.435 136.517 1.00 57.02  ? 208  GLU D CA  1 
ATOM   1554 C C   . GLU A 1 208 ? 213.437 214.661 137.810 1.00 57.02  ? 208  GLU D C   1 
ATOM   1555 O O   . GLU A 1 208 ? 214.345 214.550 138.639 1.00 57.02  ? 208  GLU D O   1 
ATOM   1556 C CB  . GLU A 1 208 ? 214.546 214.629 135.567 1.00 57.02  ? 208  GLU D CB  1 
ATOM   1557 C CG  . GLU A 1 208 ? 214.053 213.219 135.296 1.00 57.02  ? 208  GLU D CG  1 
ATOM   1558 C CD  . GLU A 1 208 ? 215.028 212.414 134.460 1.00 57.02  ? 208  GLU D CD  1 
ATOM   1559 O OE1 . GLU A 1 208 ? 216.119 212.937 134.150 1.00 57.02  ? 208  GLU D OE1 1 
ATOM   1560 O OE2 . GLU A 1 208 ? 214.704 211.259 134.113 1.00 57.02  ? 208  GLU D OE2 1 
ATOM   1561 N N   . VAL A 1 209 ? 212.228 214.130 137.976 1.00 56.91  ? 209  VAL D N   1 
ATOM   1562 C CA  . VAL A 1 209 ? 211.886 213.283 139.113 1.00 56.91  ? 209  VAL D CA  1 
ATOM   1563 C C   . VAL A 1 209 ? 211.075 212.102 138.599 1.00 56.91  ? 209  VAL D C   1 
ATOM   1564 O O   . VAL A 1 209 ? 210.138 212.279 137.814 1.00 56.91  ? 209  VAL D O   1 
ATOM   1565 C CB  . VAL A 1 209 ? 211.105 214.052 140.198 1.00 56.91  ? 209  VAL D CB  1 
ATOM   1566 C CG1 . VAL A 1 209 ? 212.052 214.907 141.024 1.00 56.91  ? 209  VAL D CG1 1 
ATOM   1567 C CG2 . VAL A 1 209 ? 210.028 214.916 139.568 1.00 56.91  ? 209  VAL D CG2 1 
ATOM   1568 N N   . ASN A 1 210 ? 211.439 210.898 139.034 1.00 59.20  ? 210  ASN D N   1 
ATOM   1569 C CA  . ASN A 1 210 ? 210.781 209.673 138.609 1.00 59.20  ? 210  ASN D CA  1 
ATOM   1570 C C   . ASN A 1 210 ? 210.520 208.788 139.821 1.00 59.20  ? 210  ASN D C   1 
ATOM   1571 O O   . ASN A 1 210 ? 211.039 209.021 140.915 1.00 59.20  ? 210  ASN D O   1 
ATOM   1572 C CB  . ASN A 1 210 ? 211.621 208.915 137.571 1.00 59.20  ? 210  ASN D CB  1 
ATOM   1573 C CG  . ASN A 1 210 ? 211.823 209.704 136.294 1.00 59.20  ? 210  ASN D CG  1 
ATOM   1574 O OD1 . ASN A 1 210 ? 210.926 210.413 135.840 1.00 59.20  ? 210  ASN D OD1 1 
ATOM   1575 N ND2 . ASN A 1 210 ? 213.007 209.584 135.706 1.00 59.20  ? 210  ASN D ND2 1 
ATOM   1576 N N   . GLY A 1 211 ? 209.700 207.761 139.611 1.00 61.02  ? 211  GLY D N   1 
ATOM   1577 C CA  . GLY A 1 211 ? 209.402 206.791 140.642 1.00 61.02  ? 211  GLY D CA  1 
ATOM   1578 C C   . GLY A 1 211 ? 208.285 207.167 141.590 1.00 61.02  ? 211  GLY D C   1 
ATOM   1579 O O   . GLY A 1 211 ? 207.983 206.386 142.501 1.00 61.02  ? 211  GLY D O   1 
ATOM   1580 N N   . VAL A 1 212 ? 207.662 208.329 141.411 1.00 59.33  ? 212  VAL D N   1 
ATOM   1581 C CA  . VAL A 1 212 ? 206.569 208.782 142.263 1.00 59.33  ? 212  VAL D CA  1 
ATOM   1582 C C   . VAL A 1 212 ? 205.342 208.999 141.389 1.00 59.33  ? 212  VAL D C   1 
ATOM   1583 O O   . VAL A 1 212 ? 205.414 209.701 140.373 1.00 59.33  ? 212  VAL D O   1 
ATOM   1584 C CB  . VAL A 1 212 ? 206.934 210.070 143.024 1.00 59.33  ? 212  VAL D CB  1 
ATOM   1585 C CG1 . VAL A 1 212 ? 205.819 210.451 143.982 1.00 59.33  ? 212  VAL D CG1 1 
ATOM   1586 C CG2 . VAL A 1 212 ? 208.247 209.892 143.771 1.00 59.33  ? 212  VAL D CG2 1 
ATOM   1587 N N   . ASP A 1 213 ? 204.222 208.402 141.786 1.00 65.19  ? 213  ASP D N   1 
ATOM   1588 C CA  . ASP A 1 213 ? 202.997 208.512 141.005 1.00 65.19  ? 213  ASP D CA  1 
ATOM   1589 C C   . ASP A 1 213 ? 202.401 209.907 141.143 1.00 65.19  ? 213  ASP D C   1 
ATOM   1590 O O   . ASP A 1 213 ? 202.194 210.399 142.257 1.00 65.19  ? 213  ASP D O   1 
ATOM   1591 C CB  . ASP A 1 213 ? 201.988 207.456 141.453 1.00 65.19  ? 213  ASP D CB  1 
ATOM   1592 C CG  . ASP A 1 213 ? 202.498 206.043 141.259 1.00 65.19  ? 213  ASP D CG  1 
ATOM   1593 O OD1 . ASP A 1 213 ? 203.637 205.882 140.773 1.00 65.19  ? 213  ASP D OD1 1 
ATOM   1594 O OD2 . ASP A 1 213 ? 201.760 205.092 141.592 1.00 65.19  ? 213  ASP D OD2 1 
ATOM   1595 N N   . GLY A 1 214 ? 202.124 210.544 140.005 1.00 59.91  ? 214  GLY D N   1 
ATOM   1596 C CA  . GLY A 1 214 ? 201.532 211.863 139.982 1.00 59.91  ? 214  GLY D CA  1 
ATOM   1597 C C   . GLY A 1 214 ? 202.501 213.014 140.134 1.00 59.91  ? 214  GLY D C   1 
ATOM   1598 O O   . GLY A 1 214 ? 202.181 214.131 139.713 1.00 59.91  ? 214  GLY D O   1 
ATOM   1599 N N   . TYR A 1 215 ? 203.676 212.784 140.720 1.00 57.03  ? 215  TYR D N   1 
ATOM   1600 C CA  . TYR A 1 215 ? 204.670 213.828 140.922 1.00 57.03  ? 215  TYR D CA  1 
ATOM   1601 C C   . TYR A 1 215 ? 205.822 213.740 139.927 1.00 57.03  ? 215  TYR D C   1 
ATOM   1602 O O   . TYR A 1 215 ? 206.865 214.367 140.140 1.00 57.03  ? 215  TYR D O   1 
ATOM   1603 C CB  . TYR A 1 215 ? 205.204 213.777 142.354 1.00 57.03  ? 215  TYR D CB  1 
ATOM   1604 C CG  . TYR A 1 215 ? 204.165 214.089 143.407 1.00 57.03  ? 215  TYR D CG  1 
ATOM   1605 C CD1 . TYR A 1 215 ? 203.933 215.396 143.813 1.00 57.03  ? 215  TYR D CD1 1 
ATOM   1606 C CD2 . TYR A 1 215 ? 203.418 213.079 143.996 1.00 57.03  ? 215  TYR D CD2 1 
ATOM   1607 C CE1 . TYR A 1 215 ? 202.986 215.687 144.774 1.00 57.03  ? 215  TYR D CE1 1 
ATOM   1608 C CE2 . TYR A 1 215 ? 202.468 213.360 144.959 1.00 57.03  ? 215  TYR D CE2 1 
ATOM   1609 C CZ  . TYR A 1 215 ? 202.256 214.666 145.344 1.00 57.03  ? 215  TYR D CZ  1 
ATOM   1610 O OH  . TYR A 1 215 ? 201.312 214.953 146.302 1.00 57.03  ? 215  TYR D OH  1 
ATOM   1611 N N   . ASP A 1 216 ? 205.657 212.979 138.849 1.00 58.40  ? 216  ASP D N   1 
ATOM   1612 C CA  . ASP A 1 216 ? 206.708 212.858 137.851 1.00 58.40  ? 216  ASP D CA  1 
ATOM   1613 C C   . ASP A 1 216 ? 206.846 214.148 137.051 1.00 58.40  ? 216  ASP D C   1 
ATOM   1614 O O   . ASP A 1 216 ? 205.895 214.919 136.897 1.00 58.40  ? 216  ASP D O   1 
ATOM   1615 C CB  . ASP A 1 216 ? 206.422 211.688 136.909 1.00 58.40  ? 216  ASP D CB  1 
ATOM   1616 C CG  . ASP A 1 216 ? 206.587 210.343 137.585 1.00 58.40  ? 216  ASP D CG  1 
ATOM   1617 O OD1 . ASP A 1 216 ? 207.462 210.225 138.468 1.00 58.40  ? 216  ASP D OD1 1 
ATOM   1618 O OD2 . ASP A 1 216 ? 205.843 209.404 137.233 1.00 58.40  ? 216  ASP D OD2 1 
ATOM   1619 N N   . TYR A 1 217 ? 208.052 214.377 136.537 1.00 56.52  ? 217  TYR D N   1 
ATOM   1620 C CA  . TYR A 1 217 ? 208.342 215.570 135.749 1.00 56.52  ? 217  TYR D CA  1 
ATOM   1621 C C   . TYR A 1 217 ? 209.453 215.232 134.769 1.00 56.52  ? 217  TYR D C   1 
ATOM   1622 O O   . TYR A 1 217 ? 210.572 214.920 135.187 1.00 56.52  ? 217  TYR D O   1 
ATOM   1623 C CB  . TYR A 1 217 ? 208.747 216.738 136.650 1.00 56.52  ? 217  TYR D CB  1 
ATOM   1624 C CG  . TYR A 1 217 ? 208.626 218.097 135.999 1.00 56.52  ? 217  TYR D CG  1 
ATOM   1625 C CD1 . TYR A 1 217 ? 209.697 218.663 135.320 1.00 56.52  ? 217  TYR D CD1 1 
ATOM   1626 C CD2 . TYR A 1 217 ? 207.440 218.815 136.067 1.00 56.52  ? 217  TYR D CD2 1 
ATOM   1627 C CE1 . TYR A 1 217 ? 209.588 219.906 134.726 1.00 56.52  ? 217  TYR D CE1 1 
ATOM   1628 C CE2 . TYR A 1 217 ? 207.323 220.057 135.477 1.00 56.52  ? 217  TYR D CE2 1 
ATOM   1629 C CZ  . TYR A 1 217 ? 208.399 220.598 134.808 1.00 56.52  ? 217  TYR D CZ  1 
ATOM   1630 O OH  . TYR A 1 217 ? 208.282 221.836 134.219 1.00 56.52  ? 217  TYR D OH  1 
ATOM   1631 N N   . SER A 1 218 ? 209.147 215.292 133.477 1.00 57.92  ? 218  SER D N   1 
ATOM   1632 C CA  . SER A 1 218 ? 210.112 214.939 132.444 1.00 57.92  ? 218  SER D CA  1 
ATOM   1633 C C   . SER A 1 218 ? 211.030 216.129 132.169 1.00 57.92  ? 218  SER D C   1 
ATOM   1634 O O   . SER A 1 218 ? 211.039 217.125 132.898 1.00 57.92  ? 218  SER D O   1 
ATOM   1635 C CB  . SER A 1 218 ? 209.389 214.467 131.185 1.00 57.92  ? 218  SER D CB  1 
ATOM   1636 O OG  . SER A 1 218 ? 208.558 215.486 130.660 1.00 57.92  ? 218  SER D OG  1 
ATOM   1637 N N   . ARG A 1 219 ? 211.820 216.035 131.102 1.00 57.16  ? 219  ARG D N   1 
ATOM   1638 C CA  . ARG A 1 219 ? 212.788 217.066 130.746 1.00 57.16  ? 219  ARG D CA  1 
ATOM   1639 C C   . ARG A 1 219 ? 212.249 218.067 129.732 1.00 57.16  ? 219  ARG D C   1 
ATOM   1640 O O   . ARG A 1 219 ? 212.496 219.268 129.869 1.00 57.16  ? 219  ARG D O   1 
ATOM   1641 C CB  . ARG A 1 219 ? 214.064 216.415 130.205 1.00 57.16  ? 219  ARG D CB  1 
ATOM   1642 C CG  . ARG A 1 219 ? 214.712 215.455 131.190 1.00 57.16  ? 219  ARG D CG  1 
ATOM   1643 C CD  . ARG A 1 219 ? 215.733 214.561 130.514 1.00 57.16  ? 219  ARG D CD  1 
ATOM   1644 N NE  . ARG A 1 219 ? 216.287 213.574 131.435 1.00 57.16  ? 219  ARG D NE  1 
ATOM   1645 C CZ  . ARG A 1 219 ? 217.129 212.610 131.078 1.00 57.16  ? 219  ARG D CZ  1 
ATOM   1646 N NH1 . ARG A 1 219 ? 217.582 211.754 131.983 1.00 57.16  ? 219  ARG D NH1 1 
ATOM   1647 N NH2 . ARG A 1 219 ? 217.515 212.499 129.815 1.00 57.16  ? 219  ARG D NH2 1 
ATOM   1648 N N   . GLY A 1 220 ? 211.519 217.603 128.715 1.00 56.13  ? 220  GLY D N   1 
ATOM   1649 C CA  . GLY A 1 220 ? 210.875 218.521 127.791 1.00 56.13  ? 220  GLY D CA  1 
ATOM   1650 C C   . GLY A 1 220 ? 209.700 219.263 128.392 1.00 56.13  ? 220  GLY D C   1 
ATOM   1651 O O   . GLY A 1 220 ? 209.365 220.361 127.928 1.00 56.13  ? 220  GLY D O   1 
ATOM   1652 N N   . GLN A 1 221 ? 209.066 218.686 129.416 1.00 57.21  ? 221  GLN D N   1 
ATOM   1653 C CA  . GLN A 1 221 ? 207.987 219.384 130.103 1.00 57.21  ? 221  GLN D CA  1 
ATOM   1654 C C   . GLN A 1 221 ? 208.488 220.661 130.760 1.00 57.21  ? 221  GLN D C   1 
ATOM   1655 O O   . GLN A 1 221 ? 207.729 221.626 130.895 1.00 57.21  ? 221  GLN D O   1 
ATOM   1656 C CB  . GLN A 1 221 ? 207.340 218.464 131.140 1.00 57.21  ? 221  GLN D CB  1 
ATOM   1657 C CG  . GLN A 1 221 ? 206.072 219.023 131.764 1.00 57.21  ? 221  GLN D CG  1 
ATOM   1658 C CD  . GLN A 1 221 ? 205.417 218.050 132.722 1.00 57.21  ? 221  GLN D CD  1 
ATOM   1659 O OE1 . GLN A 1 221 ? 205.885 216.925 132.899 1.00 57.21  ? 221  GLN D OE1 1 
ATOM   1660 N NE2 . GLN A 1 221 ? 204.326 218.478 133.347 1.00 57.21  ? 221  GLN D NE2 1 
ATOM   1661 N N   . LEU A 1 222 ? 209.761 220.694 131.160 1.00 55.94  ? 222  LEU D N   1 
ATOM   1662 C CA  . LEU A 1 222 ? 210.345 221.930 131.669 1.00 55.94  ? 222  LEU D CA  1 
ATOM   1663 C C   . LEU A 1 222 ? 210.325 223.019 130.605 1.00 55.94  ? 222  LEU D C   1 
ATOM   1664 O O   . LEU A 1 222 ? 209.923 224.158 130.871 1.00 55.94  ? 222  LEU D O   1 
ATOM   1665 C CB  . LEU A 1 222 ? 211.773 221.675 132.152 1.00 55.94  ? 222  LEU D CB  1 
ATOM   1666 C CG  . LEU A 1 222 ? 212.561 222.913 132.583 1.00 55.94  ? 222  LEU D CG  1 
ATOM   1667 C CD1 . LEU A 1 222 ? 211.952 223.534 133.831 1.00 55.94  ? 222  LEU D CD1 1 
ATOM   1668 C CD2 . LEU A 1 222 ? 214.024 222.571 132.806 1.00 55.94  ? 222  LEU D CD2 1 
ATOM   1669 N N   . ILE A 1 223 ? 210.755 222.683 129.386 1.00 55.29  ? 223  ILE D N   1 
ATOM   1670 C CA  . ILE A 1 223 ? 210.743 223.652 128.294 1.00 55.29  ? 223  ILE D CA  1 
ATOM   1671 C C   . ILE A 1 223 ? 209.317 224.090 127.989 1.00 55.29  ? 223  ILE D C   1 
ATOM   1672 O O   . ILE A 1 223 ? 209.051 225.277 127.760 1.00 55.29  ? 223  ILE D O   1 
ATOM   1673 C CB  . ILE A 1 223 ? 211.431 223.064 127.048 1.00 55.29  ? 223  ILE D CB  1 
ATOM   1674 C CG1 . ILE A 1 223 ? 212.844 222.592 127.390 1.00 55.29  ? 223  ILE D CG1 1 
ATOM   1675 C CG2 . ILE A 1 223 ? 211.469 224.088 125.925 1.00 55.29  ? 223  ILE D CG2 1 
ATOM   1676 C CD1 . ILE A 1 223 ? 213.588 221.999 126.214 1.00 55.29  ? 223  ILE D CD1 1 
ATOM   1677 N N   . GLU A 1 224 ? 208.377 223.140 127.987 1.00 57.74  ? 224  GLU D N   1 
ATOM   1678 C CA  . GLU A 1 224 ? 206.986 223.483 127.707 1.00 57.74  ? 224  GLU D CA  1 
ATOM   1679 C C   . GLU A 1 224 ? 206.425 224.435 128.759 1.00 57.74  ? 224  GLU D C   1 
ATOM   1680 O O   . GLU A 1 224 ? 205.760 225.423 128.422 1.00 57.74  ? 224  GLU D O   1 
ATOM   1681 C CB  . GLU A 1 224 ? 206.139 222.214 127.625 1.00 57.74  ? 224  GLU D CB  1 
ATOM   1682 C CG  . GLU A 1 224 ? 206.534 221.278 126.495 1.00 57.74  ? 224  GLU D CG  1 
ATOM   1683 C CD  . GLU A 1 224 ? 205.681 220.026 126.451 1.00 57.74  ? 224  GLU D CD  1 
ATOM   1684 O OE1 . GLU A 1 224 ? 204.782 219.888 127.307 1.00 57.74  ? 224  GLU D OE1 1 
ATOM   1685 O OE2 . GLU A 1 224 ? 205.910 219.181 125.560 1.00 57.74  ? 224  GLU D OE2 1 
ATOM   1686 N N   . ASP A 1 225 ? 206.689 224.158 130.038 1.00 57.23  ? 225  ASP D N   1 
ATOM   1687 C CA  . ASP A 1 225 ? 206.185 225.017 131.104 1.00 57.23  ? 225  ASP D CA  1 
ATOM   1688 C C   . ASP A 1 225 ? 206.831 226.394 131.057 1.00 57.23  ? 225  ASP D C   1 
ATOM   1689 O O   . ASP A 1 225 ? 206.160 227.406 131.293 1.00 57.23  ? 225  ASP D O   1 
ATOM   1690 C CB  . ASP A 1 225 ? 206.421 224.362 132.465 1.00 57.23  ? 225  ASP D CB  1 
ATOM   1691 C CG  . ASP A 1 225 ? 205.607 223.098 132.652 1.00 57.23  ? 225  ASP D CG  1 
ATOM   1692 O OD1 . ASP A 1 225 ? 204.533 222.982 132.026 1.00 57.23  ? 225  ASP D OD1 1 
ATOM   1693 O OD2 . ASP A 1 225 ? 206.040 222.221 133.429 1.00 57.23  ? 225  ASP D OD2 1 
ATOM   1694 N N   . VAL A 1 226 ? 208.131 226.457 130.757 1.00 56.39  ? 226  VAL D N   1 
ATOM   1695 C CA  . VAL A 1 226 ? 208.799 227.750 130.648 1.00 56.39  ? 226  VAL D CA  1 
ATOM   1696 C C   . VAL A 1 226 ? 208.203 228.561 129.505 1.00 56.39  ? 226  VAL D C   1 
ATOM   1697 O O   . VAL A 1 226 ? 207.940 229.762 129.648 1.00 56.39  ? 226  VAL D O   1 
ATOM   1698 C CB  . VAL A 1 226 ? 210.318 227.557 130.482 1.00 56.39  ? 226  VAL D CB  1 
ATOM   1699 C CG1 . VAL A 1 226 ? 210.980 228.864 130.089 1.00 56.39  ? 226  VAL D CG1 1 
ATOM   1700 C CG2 . VAL A 1 226 ? 210.925 227.031 131.772 1.00 56.39  ? 226  VAL D CG2 1 
ATOM   1701 N N   . GLU A 1 227 ? 207.958 227.916 128.361 1.00 58.21  ? 227  GLU D N   1 
ATOM   1702 C CA  . GLU A 1 227 ? 207.369 228.625 127.230 1.00 58.21  ? 227  GLU D CA  1 
ATOM   1703 C C   . GLU A 1 227 ? 205.956 229.099 127.547 1.00 58.21  ? 227  GLU D C   1 
ATOM   1704 O O   . GLU A 1 227 ? 205.571 230.213 127.173 1.00 58.21  ? 227  GLU D O   1 
ATOM   1705 C CB  . GLU A 1 227 ? 207.373 227.735 125.987 1.00 58.21  ? 227  GLU D CB  1 
ATOM   1706 C CG  . GLU A 1 227 ? 208.756 227.491 125.407 1.00 58.21  ? 227  GLU D CG  1 
ATOM   1707 C CD  . GLU A 1 227 ? 208.713 226.725 124.100 1.00 58.21  ? 227  GLU D CD  1 
ATOM   1708 O OE1 . GLU A 1 227 ? 207.601 226.388 123.643 1.00 58.21  ? 227  GLU D OE1 1 
ATOM   1709 O OE2 . GLU A 1 227 ? 209.792 226.461 123.529 1.00 58.21  ? 227  GLU D OE2 1 
ATOM   1710 N N   . HIS A 1 228 ? 205.172 228.277 128.249 1.00 58.54  ? 228  HIS D N   1 
ATOM   1711 C CA  . HIS A 1 228 ? 203.814 228.684 128.600 1.00 58.54  ? 228  HIS D CA  1 
ATOM   1712 C C   . HIS A 1 228 ? 203.817 229.853 129.578 1.00 58.54  ? 228  HIS D C   1 
ATOM   1713 O O   . HIS A 1 228 ? 203.040 230.805 129.422 1.00 58.54  ? 228  HIS D O   1 
ATOM   1714 C CB  . HIS A 1 228 ? 203.042 227.498 129.178 1.00 58.54  ? 228  HIS D CB  1 
ATOM   1715 C CG  . HIS A 1 228 ? 202.713 226.443 128.168 1.00 58.54  ? 228  HIS D CG  1 
ATOM   1716 N ND1 . HIS A 1 228 ? 202.087 225.262 128.503 1.00 58.54  ? 228  HIS D ND1 1 
ATOM   1717 C CD2 . HIS A 1 228 ? 202.921 226.393 126.831 1.00 58.54  ? 228  HIS D CD2 1 
ATOM   1718 C CE1 . HIS A 1 228 ? 201.925 224.529 127.416 1.00 58.54  ? 228  HIS D CE1 1 
ATOM   1719 N NE2 . HIS A 1 228 ? 202.422 225.192 126.388 1.00 58.54  ? 228  HIS D NE2 1 
ATOM   1720 N N   . THR A 1 229 ? 204.688 229.806 130.590 1.00 56.87  ? 229  THR D N   1 
ATOM   1721 C CA  . THR A 1 229 ? 204.773 230.912 131.537 1.00 56.87  ? 229  THR D CA  1 
ATOM   1722 C C   . THR A 1 229 ? 205.244 232.187 130.851 1.00 56.87  ? 229  THR D C   1 
ATOM   1723 O O   . THR A 1 229 ? 204.759 233.283 131.159 1.00 56.87  ? 229  THR D O   1 
ATOM   1724 C CB  . THR A 1 229 ? 205.705 230.549 132.694 1.00 56.87  ? 229  THR D CB  1 
ATOM   1725 O OG1 . THR A 1 229 ? 206.963 230.098 132.176 1.00 56.87  ? 229  THR D OG1 1 
ATOM   1726 C CG2 . THR A 1 229 ? 205.089 229.455 133.553 1.00 56.87  ? 229  THR D CG2 1 
ATOM   1727 N N   . PHE A 1 230 ? 206.175 232.067 129.901 1.00 57.70  ? 230  PHE D N   1 
ATOM   1728 C CA  . PHE A 1 230 ? 206.626 233.250 129.177 1.00 57.70  ? 230  PHE D CA  1 
ATOM   1729 C C   . PHE A 1 230 ? 205.520 233.812 128.293 1.00 57.70  ? 230  PHE D C   1 
ATOM   1730 O O   . PHE A 1 230 ? 205.368 235.034 128.185 1.00 57.70  ? 230  PHE D O   1 
ATOM   1731 C CB  . PHE A 1 230 ? 207.865 232.925 128.344 1.00 57.70  ? 230  PHE D CB  1 
ATOM   1732 C CG  . PHE A 1 230 ? 208.441 234.116 127.639 1.00 57.70  ? 230  PHE D CG  1 
ATOM   1733 C CD1 . PHE A 1 230 ? 209.198 235.046 128.333 1.00 57.70  ? 230  PHE D CD1 1 
ATOM   1734 C CD2 . PHE A 1 230 ? 208.220 234.314 126.287 1.00 57.70  ? 230  PHE D CD2 1 
ATOM   1735 C CE1 . PHE A 1 230 ? 209.726 236.147 127.691 1.00 57.70  ? 230  PHE D CE1 1 
ATOM   1736 C CE2 . PHE A 1 230 ? 208.746 235.414 125.639 1.00 57.70  ? 230  PHE D CE2 1 
ATOM   1737 C CZ  . PHE A 1 230 ? 209.500 236.331 126.343 1.00 57.70  ? 230  PHE D CZ  1 
ATOM   1738 N N   . GLU A 1 231 ? 204.737 232.941 127.653 1.00 59.08  ? 231  GLU D N   1 
ATOM   1739 C CA  . GLU A 1 231 ? 203.616 233.417 126.850 1.00 59.08  ? 231  GLU D CA  1 
ATOM   1740 C C   . GLU A 1 231 ? 202.568 234.106 127.711 1.00 59.08  ? 231  GLU D C   1 
ATOM   1741 O O   . GLU A 1 231 ? 201.941 235.075 127.269 1.00 59.08  ? 231  GLU D O   1 
ATOM   1742 C CB  . GLU A 1 231 ? 202.988 232.257 126.075 1.00 59.08  ? 231  GLU D CB  1 
ATOM   1743 C CG  . GLU A 1 231 ? 203.840 231.737 124.928 1.00 59.08  ? 231  GLU D CG  1 
ATOM   1744 C CD  . GLU A 1 231 ? 203.952 232.726 123.785 1.00 59.08  ? 231  GLU D CD  1 
ATOM   1745 O OE1 . GLU A 1 231 ? 203.079 233.613 123.673 1.00 59.08  ? 231  GLU D OE1 1 
ATOM   1746 O OE2 . GLU A 1 231 ? 204.914 232.617 122.996 1.00 59.08  ? 231  GLU D OE2 1 
ATOM   1747 N N   . GLU A 1 232 ? 202.365 233.627 128.939 1.00 59.24  ? 232  GLU D N   1 
ATOM   1748 C CA  . GLU A 1 232 ? 201.404 234.275 129.825 1.00 59.24  ? 232  GLU D CA  1 
ATOM   1749 C C   . GLU A 1 232 ? 201.936 235.586 130.396 1.00 59.24  ? 232  GLU D C   1 
ATOM   1750 O O   . GLU A 1 232 ? 201.148 236.493 130.684 1.00 59.24  ? 232  GLU D O   1 
ATOM   1751 C CB  . GLU A 1 232 ? 201.008 233.330 130.960 1.00 59.24  ? 232  GLU D CB  1 
ATOM   1752 C CG  . GLU A 1 232 ? 200.230 232.107 130.503 1.00 59.24  ? 232  GLU D CG  1 
ATOM   1753 C CD  . GLU A 1 232 ? 199.722 231.272 131.662 1.00 59.24  ? 232  GLU D CD  1 
ATOM   1754 O OE1 . GLU A 1 232 ? 199.876 231.707 132.822 1.00 59.24  ? 232  GLU D OE1 1 
ATOM   1755 O OE2 . GLU A 1 232 ? 199.169 230.181 131.412 1.00 59.24  ? 232  GLU D OE2 1 
ATOM   1756 N N   . ILE A 1 233 ? 203.257 235.708 130.565 1.00 57.61  ? 233  ILE D N   1 
ATOM   1757 C CA  . ILE A 1 233 ? 203.838 236.933 131.116 1.00 57.61  ? 233  ILE D CA  1 
ATOM   1758 C C   . ILE A 1 233 ? 204.206 237.950 130.042 1.00 57.61  ? 233  ILE D C   1 
ATOM   1759 O O   . ILE A 1 233 ? 204.563 239.090 130.378 1.00 57.61  ? 233  ILE D O   1 
ATOM   1760 C CB  . ILE A 1 233 ? 205.081 236.600 131.968 1.00 57.61  ? 233  ILE D CB  1 
ATOM   1761 C CG1 . ILE A 1 233 ? 205.319 237.678 133.027 1.00 57.61  ? 233  ILE D CG1 1 
ATOM   1762 C CG2 . ILE A 1 233 ? 206.310 236.436 131.085 1.00 57.61  ? 233  ILE D CG2 1 
ATOM   1763 C CD1 . ILE A 1 233 ? 206.538 237.430 133.882 1.00 57.61  ? 233  ILE D CD1 1 
ATOM   1764 N N   . LYS A 1 234 ? 204.129 237.577 128.765 1.00 58.51  ? 234  LYS D N   1 
ATOM   1765 C CA  . LYS A 1 234 ? 204.526 238.488 127.694 1.00 58.51  ? 234  LYS D CA  1 
ATOM   1766 C C   . LYS A 1 234 ? 203.790 239.828 127.678 1.00 58.51  ? 234  LYS D C   1 
ATOM   1767 O O   . LYS A 1 234 ? 204.441 240.841 127.374 1.00 58.51  ? 234  LYS D O   1 
ATOM   1768 C CB  . LYS A 1 234 ? 204.372 237.776 126.343 1.00 58.51  ? 234  LYS D CB  1 
ATOM   1769 C CG  . LYS A 1 234 ? 204.967 238.533 125.167 1.00 58.51  ? 234  LYS D CG  1 
ATOM   1770 C CD  . LYS A 1 234 ? 204.890 237.714 123.889 1.00 58.51  ? 234  LYS D CD  1 
ATOM   1771 C CE  . LYS A 1 234 ? 203.452 237.371 123.537 1.00 58.51  ? 234  LYS D CE  1 
ATOM   1772 N NZ  . LYS A 1 234 ? 203.363 236.565 122.288 1.00 58.51  ? 234  LYS D NZ  1 
ATOM   1773 N N   . PRO A 1 235 ? 202.480 239.920 127.951 1.00 56.76  ? 235  PRO D N   1 
ATOM   1774 C CA  . PRO A 1 235 ? 201.837 241.250 127.907 1.00 56.76  ? 235  PRO D CA  1 
ATOM   1775 C C   . PRO A 1 235 ? 202.419 242.250 128.895 1.00 56.76  ? 235  PRO D C   1 
ATOM   1776 O O   . PRO A 1 235 ? 202.618 243.423 128.542 1.00 56.76  ? 235  PRO D O   1 
ATOM   1777 C CB  . PRO A 1 235 ? 200.368 240.934 128.219 1.00 56.76  ? 235  PRO D CB  1 
ATOM   1778 C CG  . PRO A 1 235 ? 200.188 239.537 127.767 1.00 56.76  ? 235  PRO D CG  1 
ATOM   1779 C CD  . PRO A 1 235 ? 201.478 238.846 128.088 1.00 56.76  ? 235  PRO D CD  1 
ATOM   1780 N N   . LEU A 1 236 ? 202.688 241.822 130.131 1.00 55.43  ? 236  LEU D N   1 
ATOM   1781 C CA  . LEU A 1 236 ? 203.267 242.729 131.116 1.00 55.43  ? 236  LEU D CA  1 
ATOM   1782 C C   . LEU A 1 236 ? 204.641 243.214 130.675 1.00 55.43  ? 236  LEU D C   1 
ATOM   1783 O O   . LEU A 1 236 ? 204.957 244.405 130.796 1.00 55.43  ? 236  LEU D O   1 
ATOM   1784 C CB  . LEU A 1 236 ? 203.352 242.041 132.479 1.00 55.43  ? 236  LEU D CB  1 
ATOM   1785 C CG  . LEU A 1 236 ? 204.022 242.838 133.600 1.00 55.43  ? 236  LEU D CG  1 
ATOM   1786 C CD1 . LEU A 1 236 ? 203.280 244.140 133.854 1.00 55.43  ? 236  LEU D CD1 1 
ATOM   1787 C CD2 . LEU A 1 236 ? 204.108 242.009 134.871 1.00 55.43  ? 236  LEU D CD2 1 
ATOM   1788 N N   . TYR A 1 237 ? 205.471 242.308 130.153 1.00 56.86  ? 237  TYR D N   1 
ATOM   1789 C CA  . TYR A 1 237 ? 206.787 242.717 129.681 1.00 56.86  ? 237  TYR D CA  1 
ATOM   1790 C C   . TYR A 1 237 ? 206.689 243.631 128.469 1.00 56.86  ? 237  TYR D C   1 
ATOM   1791 O O   . TYR A 1 237 ? 207.508 244.540 128.321 1.00 56.86  ? 237  TYR D O   1 
ATOM   1792 C CB  . TYR A 1 237 ? 207.648 241.501 129.349 1.00 56.86  ? 237  TYR D CB  1 
ATOM   1793 C CG  . TYR A 1 237 ? 208.999 241.882 128.788 1.00 56.86  ? 237  TYR D CG  1 
ATOM   1794 C CD1 . TYR A 1 237 ? 209.977 242.435 129.604 1.00 56.86  ? 237  TYR D CD1 1 
ATOM   1795 C CD2 . TYR A 1 237 ? 209.291 241.704 127.443 1.00 56.86  ? 237  TYR D CD2 1 
ATOM   1796 C CE1 . TYR A 1 237 ? 211.211 242.793 129.098 1.00 56.86  ? 237  TYR D CE1 1 
ATOM   1797 C CE2 . TYR A 1 237 ? 210.523 242.059 126.927 1.00 56.86  ? 237  TYR D CE2 1 
ATOM   1798 C CZ  . TYR A 1 237 ? 211.479 242.602 127.760 1.00 56.86  ? 237  TYR D CZ  1 
ATOM   1799 O OH  . TYR A 1 237 ? 212.707 242.957 127.253 1.00 56.86  ? 237  TYR D OH  1 
ATOM   1800 N N   . GLU A 1 238 ? 205.701 243.418 127.598 1.00 58.34  ? 238  GLU D N   1 
ATOM   1801 C CA  . GLU A 1 238 ? 205.534 244.303 126.450 1.00 58.34  ? 238  GLU D CA  1 
ATOM   1802 C C   . GLU A 1 238 ? 205.131 245.704 126.890 1.00 58.34  ? 238  GLU D C   1 
ATOM   1803 O O   . GLU A 1 238 ? 205.642 246.698 126.360 1.00 58.34  ? 238  GLU D O   1 
ATOM   1804 C CB  . GLU A 1 238 ? 204.504 243.726 125.480 1.00 58.34  ? 238  GLU D CB  1 
ATOM   1805 C CG  . GLU A 1 238 ? 204.993 242.518 124.701 1.00 58.34  ? 238  GLU D CG  1 
ATOM   1806 C CD  . GLU A 1 238 ? 203.968 242.014 123.706 1.00 58.34  ? 238  GLU D CD  1 
ATOM   1807 O OE1 . GLU A 1 238 ? 202.866 242.598 123.639 1.00 58.34  ? 238  GLU D OE1 1 
ATOM   1808 O OE2 . GLU A 1 238 ? 204.264 241.034 122.990 1.00 58.34  ? 238  GLU D OE2 1 
ATOM   1809 N N   . HIS A 1 239 ? 204.225 245.804 127.866 1.00 57.94  ? 239  HIS D N   1 
ATOM   1810 C CA  . HIS A 1 239 ? 203.854 247.119 128.381 1.00 57.94  ? 239  HIS D CA  1 
ATOM   1811 C C   . HIS A 1 239 ? 205.035 247.797 129.068 1.00 57.94  ? 239  HIS D C   1 
ATOM   1812 O O   . HIS A 1 239 ? 205.259 249.003 128.892 1.00 57.94  ? 239  HIS D O   1 
ATOM   1813 C CB  . HIS A 1 239 ? 202.667 246.996 129.336 1.00 57.94  ? 239  HIS D CB  1 
ATOM   1814 C CG  . HIS A 1 239 ? 201.348 246.855 128.643 1.00 57.94  ? 239  HIS D CG  1 
ATOM   1815 N ND1 . HIS A 1 239 ? 200.604 247.939 128.233 1.00 57.94  ? 239  HIS D ND1 1 
ATOM   1816 C CD2 . HIS A 1 239 ? 200.642 245.757 128.285 1.00 57.94  ? 239  HIS D CD2 1 
ATOM   1817 C CE1 . HIS A 1 239 ? 199.495 247.516 127.654 1.00 57.94  ? 239  HIS D CE1 1 
ATOM   1818 N NE2 . HIS A 1 239 ? 199.493 246.196 127.672 1.00 57.94  ? 239  HIS D NE2 1 
ATOM   1819 N N   . LEU A 1 240 ? 205.811 247.036 129.845 1.00 56.69  ? 240  LEU D N   1 
ATOM   1820 C CA  . LEU A 1 240 ? 206.984 247.607 130.499 1.00 56.69  ? 240  LEU D CA  1 
ATOM   1821 C C   . LEU A 1 240 ? 208.017 248.064 129.476 1.00 56.69  ? 240  LEU D C   1 
ATOM   1822 O O   . LEU A 1 240 ? 208.645 249.115 129.643 1.00 56.69  ? 240  LEU D O   1 
ATOM   1823 C CB  . LEU A 1 240 ? 207.594 246.588 131.462 1.00 56.69  ? 240  LEU D CB  1 
ATOM   1824 C CG  . LEU A 1 240 ? 208.801 247.056 132.277 1.00 56.69  ? 240  LEU D CG  1 
ATOM   1825 C CD1 . LEU A 1 240 ? 208.422 248.225 133.172 1.00 56.69  ? 240  LEU D CD1 1 
ATOM   1826 C CD2 . LEU A 1 240 ? 209.373 245.912 133.097 1.00 56.69  ? 240  LEU D CD2 1 
ATOM   1827 N N   . HIS A 1 241 ? 208.199 247.290 128.404 1.00 57.84  ? 241  HIS D N   1 
ATOM   1828 C CA  . HIS A 1 241 ? 209.135 247.666 127.351 1.00 57.84  ? 241  HIS D CA  1 
ATOM   1829 C C   . HIS A 1 241 ? 208.673 248.923 126.630 1.00 57.84  ? 241  HIS D C   1 
ATOM   1830 O O   . HIS A 1 241 ? 209.488 249.796 126.314 1.00 57.84  ? 241  HIS D O   1 
ATOM   1831 C CB  . HIS A 1 241 ? 209.299 246.505 126.369 1.00 57.84  ? 241  HIS D CB  1 
ATOM   1832 C CG  . HIS A 1 241 ? 210.184 246.816 125.202 1.00 57.84  ? 241  HIS D CG  1 
ATOM   1833 N ND1 . HIS A 1 241 ? 209.700 247.313 124.012 1.00 57.84  ? 241  HIS D ND1 1 
ATOM   1834 C CD2 . HIS A 1 241 ? 211.523 246.689 125.040 1.00 57.84  ? 241  HIS D CD2 1 
ATOM   1835 C CE1 . HIS A 1 241 ? 210.702 247.485 123.168 1.00 57.84  ? 241  HIS D CE1 1 
ATOM   1836 N NE2 . HIS A 1 241 ? 211.819 247.114 123.768 1.00 57.84  ? 241  HIS D NE2 1 
ATOM   1837 N N   . ALA A 1 242 ? 207.369 249.037 126.367 1.00 57.66  ? 242  ALA D N   1 
ATOM   1838 C CA  . ALA A 1 242 ? 206.847 250.248 125.741 1.00 57.66  ? 242  ALA D CA  1 
ATOM   1839 C C   . ALA A 1 242 ? 207.058 251.463 126.635 1.00 57.66  ? 242  ALA D C   1 
ATOM   1840 O O   . ALA A 1 242 ? 207.439 252.538 126.155 1.00 57.66  ? 242  ALA D O   1 
ATOM   1841 C CB  . ALA A 1 242 ? 205.365 250.072 125.411 1.00 57.66  ? 242  ALA D CB  1 
ATOM   1842 N N   . TYR A 1 243 ? 206.828 251.310 127.941 1.00 56.65  ? 243  TYR D N   1 
ATOM   1843 C CA  . TYR A 1 243 ? 207.043 252.425 128.859 1.00 56.65  ? 243  TYR D CA  1 
ATOM   1844 C C   . TYR A 1 243 ? 208.515 252.819 128.921 1.00 56.65  ? 243  TYR D C   1 
ATOM   1845 O O   . TYR A 1 243 ? 208.848 254.011 128.901 1.00 56.65  ? 243  TYR D O   1 
ATOM   1846 C CB  . TYR A 1 243 ? 206.522 252.068 130.251 1.00 56.65  ? 243  TYR D CB  1 
ATOM   1847 C CG  . TYR A 1 243 ? 206.657 253.186 131.259 1.00 56.65  ? 243  TYR D CG  1 
ATOM   1848 C CD1 . TYR A 1 243 ? 205.741 254.228 131.296 1.00 56.65  ? 243  TYR D CD1 1 
ATOM   1849 C CD2 . TYR A 1 243 ? 207.700 253.199 132.176 1.00 56.65  ? 243  TYR D CD2 1 
ATOM   1850 C CE1 . TYR A 1 243 ? 205.860 255.252 132.215 1.00 56.65  ? 243  TYR D CE1 1 
ATOM   1851 C CE2 . TYR A 1 243 ? 207.827 254.219 133.098 1.00 56.65  ? 243  TYR D CE2 1 
ATOM   1852 C CZ  . TYR A 1 243 ? 206.904 255.241 133.114 1.00 56.65  ? 243  TYR D CZ  1 
ATOM   1853 O OH  . TYR A 1 243 ? 207.027 256.258 134.032 1.00 56.65  ? 243  TYR D OH  1 
ATOM   1854 N N   . VAL A 1 244 ? 209.411 251.830 128.996 1.00 57.72  ? 244  VAL D N   1 
ATOM   1855 C CA  . VAL A 1 244 ? 210.842 252.119 129.044 1.00 57.72  ? 244  VAL D CA  1 
ATOM   1856 C C   . VAL A 1 244 ? 211.294 252.795 127.756 1.00 57.72  ? 244  VAL D C   1 
ATOM   1857 O O   . VAL A 1 244 ? 212.118 253.715 127.778 1.00 57.72  ? 244  VAL D O   1 
ATOM   1858 C CB  . VAL A 1 244 ? 211.637 250.829 129.323 1.00 57.72  ? 244  VAL D CB  1 
ATOM   1859 C CG1 . VAL A 1 244 ? 213.125 251.057 129.107 1.00 57.72  ? 244  VAL D CG1 1 
ATOM   1860 C CG2 . VAL A 1 244 ? 211.380 250.348 130.741 1.00 57.72  ? 244  VAL D CG2 1 
ATOM   1861 N N   . ARG A 1 245 ? 210.750 252.365 126.616 1.00 59.91  ? 245  ARG D N   1 
ATOM   1862 C CA  . ARG A 1 245 ? 211.104 252.986 125.345 1.00 59.91  ? 245  ARG D CA  1 
ATOM   1863 C C   . ARG A 1 245 ? 210.611 254.426 125.278 1.00 59.91  ? 245  ARG D C   1 
ATOM   1864 O O   . ARG A 1 245 ? 211.338 255.317 124.820 1.00 59.91  ? 245  ARG D O   1 
ATOM   1865 C CB  . ARG A 1 245 ? 210.534 252.162 124.192 1.00 59.91  ? 245  ARG D CB  1 
ATOM   1866 C CG  . ARG A 1 245 ? 210.733 252.769 122.816 1.00 59.91  ? 245  ARG D CG  1 
ATOM   1867 C CD  . ARG A 1 245 ? 210.217 251.828 121.742 1.00 59.91  ? 245  ARG D CD  1 
ATOM   1868 N NE  . ARG A 1 245 ? 208.851 251.392 122.016 1.00 59.91  ? 245  ARG D NE  1 
ATOM   1869 C CZ  . ARG A 1 245 ? 208.196 250.488 121.294 1.00 59.91  ? 245  ARG D CZ  1 
ATOM   1870 N NH1 . ARG A 1 245 ? 206.955 250.152 121.618 1.00 59.91  ? 245  ARG D NH1 1 
ATOM   1871 N NH2 . ARG A 1 245 ? 208.781 249.920 120.249 1.00 59.91  ? 245  ARG D NH2 1 
ATOM   1872 N N   . ALA A 1 246 ? 209.380 254.674 125.734 1.00 58.71  ? 246  ALA D N   1 
ATOM   1873 C CA  . ALA A 1 246 ? 208.857 256.036 125.743 1.00 58.71  ? 246  ALA D CA  1 
ATOM   1874 C C   . ALA A 1 246 ? 209.672 256.933 126.666 1.00 58.71  ? 246  ALA D C   1 
ATOM   1875 O O   . ALA A 1 246 ? 209.869 258.119 126.375 1.00 58.71  ? 246  ALA D O   1 
ATOM   1876 C CB  . ALA A 1 246 ? 207.386 256.031 126.156 1.00 58.71  ? 246  ALA D CB  1 
ATOM   1877 N N   . LYS A 1 247 ? 210.156 256.386 127.783 1.00 57.24  ? 247  LYS D N   1 
ATOM   1878 C CA  . LYS A 1 247 ? 210.967 257.187 128.696 1.00 57.24  ? 247  LYS D CA  1 
ATOM   1879 C C   . LYS A 1 247 ? 212.362 257.435 128.134 1.00 57.24  ? 247  LYS D C   1 
ATOM   1880 O O   . LYS A 1 247 ? 212.926 258.520 128.317 1.00 57.24  ? 247  LYS D O   1 
ATOM   1881 C CB  . LYS A 1 247 ? 211.047 256.508 130.062 1.00 57.24  ? 247  LYS D CB  1 
ATOM   1882 C CG  . LYS A 1 247 ? 209.835 256.752 130.943 1.00 57.24  ? 247  LYS D CG  1 
ATOM   1883 C CD  . LYS A 1 247 ? 209.696 258.229 131.276 1.00 57.24  ? 247  LYS D CD  1 
ATOM   1884 C CE  . LYS A 1 247 ? 208.466 258.495 132.125 1.00 57.24  ? 247  LYS D CE  1 
ATOM   1885 N NZ  . LYS A 1 247 ? 207.212 258.128 131.412 1.00 57.24  ? 247  LYS D NZ  1 
ATOM   1886 N N   . LEU A 1 248 ? 212.937 256.444 127.450 1.00 59.50  ? 248  LEU D N   1 
ATOM   1887 C CA  . LEU A 1 248 ? 214.271 256.591 126.883 1.00 59.50  ? 248  LEU D CA  1 
ATOM   1888 C C   . LEU A 1 248 ? 214.289 257.459 125.633 1.00 59.50  ? 248  LEU D C   1 
ATOM   1889 O O   . LEU A 1 248 ? 215.347 257.991 125.283 1.00 59.50  ? 248  LEU D O   1 
ATOM   1890 C CB  . LEU A 1 248 ? 214.864 255.216 126.561 1.00 59.50  ? 248  LEU D CB  1 
ATOM   1891 C CG  . LEU A 1 248 ? 215.782 254.587 127.613 1.00 59.50  ? 248  LEU D CG  1 
ATOM   1892 C CD1 . LEU A 1 248 ? 215.073 254.429 128.949 1.00 59.50  ? 248  LEU D CD1 1 
ATOM   1893 C CD2 . LEU A 1 248 ? 216.309 253.247 127.123 1.00 59.50  ? 248  LEU D CD2 1 
ATOM   1894 N N   . MET A 1 249 ? 213.150 257.608 124.951 1.00 62.91  ? 249  MET D N   1 
ATOM   1895 C CA  . MET A 1 249 ? 213.096 258.516 123.810 1.00 62.91  ? 249  MET D CA  1 
ATOM   1896 C C   . MET A 1 249 ? 213.359 259.961 124.211 1.00 62.91  ? 249  MET D C   1 
ATOM   1897 O O   . MET A 1 249 ? 213.778 260.760 123.366 1.00 62.91  ? 249  MET D O   1 
ATOM   1898 C CB  . MET A 1 249 ? 211.742 258.410 123.107 1.00 62.91  ? 249  MET D CB  1 
ATOM   1899 C CG  . MET A 1 249 ? 211.579 257.165 122.253 1.00 62.91  ? 249  MET D CG  1 
ATOM   1900 S SD  . MET A 1 249 ? 209.996 257.118 121.393 1.00 62.91  ? 249  MET D SD  1 
ATOM   1901 C CE  . MET A 1 249 ? 210.118 258.592 120.383 1.00 62.91  ? 249  MET D CE  1 
ATOM   1902 N N   . ASN A 1 250 ? 213.126 260.315 125.476 1.00 62.40  ? 250  ASN D N   1 
ATOM   1903 C CA  . ASN A 1 250 ? 213.411 261.671 125.932 1.00 62.40  ? 250  ASN D CA  1 
ATOM   1904 C C   . ASN A 1 250 ? 214.904 261.885 126.149 1.00 62.40  ? 250  ASN D C   1 
ATOM   1905 O O   . ASN A 1 250 ? 215.444 262.931 125.772 1.00 62.40  ? 250  ASN D O   1 
ATOM   1906 C CB  . ASN A 1 250 ? 212.639 261.966 127.218 1.00 62.40  ? 250  ASN D CB  1 
ATOM   1907 C CG  . ASN A 1 250 ? 211.138 261.879 127.030 1.00 62.40  ? 250  ASN D CG  1 
ATOM   1908 O OD1 . ASN A 1 250 ? 210.459 261.114 127.715 1.00 62.40  ? 250  ASN D OD1 1 
ATOM   1909 N ND2 . ASN A 1 250 ? 210.612 262.663 126.097 1.00 62.40  ? 250  ASN D ND2 1 
ATOM   1910 N N   . ALA A 1 251 ? 215.585 260.909 126.755 1.00 62.91  ? 251  ALA D N   1 
ATOM   1911 C CA  . ALA A 1 251 ? 217.022 261.037 126.974 1.00 62.91  ? 251  ALA D CA  1 
ATOM   1912 C C   . ALA A 1 251 ? 217.806 260.873 125.679 1.00 62.91  ? 251  ALA D C   1 
ATOM   1913 O O   . ALA A 1 251 ? 218.910 261.416 125.552 1.00 62.91  ? 251  ALA D O   1 
ATOM   1914 C CB  . ALA A 1 251 ? 217.489 260.018 128.012 1.00 62.91  ? 251  ALA D CB  1 
ATOM   1915 N N   . TYR A 1 252 ? 217.261 260.135 124.716 1.00 65.41  ? 252  TYR D N   1 
ATOM   1916 C CA  . TYR A 1 252 ? 217.891 259.940 123.411 1.00 65.41  ? 252  TYR D CA  1 
ATOM   1917 C C   . TYR A 1 252 ? 216.866 260.277 122.337 1.00 65.41  ? 252  TYR D C   1 
ATOM   1918 O O   . TYR A 1 252 ? 216.035 259.424 121.978 1.00 65.41  ? 252  TYR D O   1 
ATOM   1919 C CB  . TYR A 1 252 ? 218.404 258.515 123.251 1.00 65.41  ? 252  TYR D CB  1 
ATOM   1920 C CG  . TYR A 1 252 ? 219.292 258.052 124.385 1.00 65.41  ? 252  TYR D CG  1 
ATOM   1921 C CD1 . TYR A 1 252 ? 220.653 258.324 124.382 1.00 65.41  ? 252  TYR D CD1 1 
ATOM   1922 C CD2 . TYR A 1 252 ? 218.768 257.342 125.457 1.00 65.41  ? 252  TYR D CD2 1 
ATOM   1923 C CE1 . TYR A 1 252 ? 221.468 257.903 125.416 1.00 65.41  ? 252  TYR D CE1 1 
ATOM   1924 C CE2 . TYR A 1 252 ? 219.574 256.917 126.495 1.00 65.41  ? 252  TYR D CE2 1 
ATOM   1925 C CZ  . TYR A 1 252 ? 220.923 257.200 126.469 1.00 65.41  ? 252  TYR D CZ  1 
ATOM   1926 O OH  . TYR A 1 252 ? 221.729 256.778 127.501 1.00 65.41  ? 252  TYR D OH  1 
ATOM   1927 N N   . PRO A 1 253 ? 216.886 261.501 121.802 1.00 66.39  ? 253  PRO D N   1 
ATOM   1928 C CA  . PRO A 1 253 ? 215.810 261.898 120.879 1.00 66.39  ? 253  PRO D CA  1 
ATOM   1929 C C   . PRO A 1 253 ? 215.912 261.255 119.508 1.00 66.39  ? 253  PRO D C   1 
ATOM   1930 O O   . PRO A 1 253 ? 214.882 260.886 118.929 1.00 66.39  ? 253  PRO D O   1 
ATOM   1931 C CB  . PRO A 1 253 ? 215.966 263.423 120.808 1.00 66.39  ? 253  PRO D CB  1 
ATOM   1932 C CG  . PRO A 1 253 ? 217.414 263.658 121.082 1.00 66.39  ? 253  PRO D CG  1 
ATOM   1933 C CD  . PRO A 1 253 ? 217.830 262.600 122.068 1.00 66.39  ? 253  PRO D CD  1 
ATOM   1934 N N   . SER A 1 254 ? 217.118 261.106 118.967 1.00 67.96  ? 254  SER D N   1 
ATOM   1935 C CA  . SER A 1 254 ? 217.316 260.607 117.612 1.00 67.96  ? 254  SER D CA  1 
ATOM   1936 C C   . SER A 1 254 ? 218.170 259.345 117.604 1.00 67.96  ? 254  SER D C   1 
ATOM   1937 O O   . SER A 1 254 ? 219.040 259.168 116.748 1.00 67.96  ? 254  SER D O   1 
ATOM   1938 C CB  . SER A 1 254 ? 217.940 261.682 116.726 1.00 67.96  ? 254  SER D CB  1 
ATOM   1939 O OG  . SER A 1 254 ? 219.199 262.090 117.231 1.00 67.96  ? 254  SER D OG  1 
ATOM   1940 N N   . TYR A 1 255 ? 217.933 258.450 118.560 1.00 68.83  ? 255  TYR D N   1 
ATOM   1941 C CA  . TYR A 1 255 ? 218.674 257.196 118.614 1.00 68.83  ? 255  TYR D CA  1 
ATOM   1942 C C   . TYR A 1 255 ? 217.737 256.003 118.748 1.00 68.83  ? 255  TYR D C   1 
ATOM   1943 O O   . TYR A 1 255 ? 218.060 254.900 118.297 1.00 68.83  ? 255  TYR D O   1 
ATOM   1944 C CB  . TYR A 1 255 ? 219.679 257.219 119.768 1.00 68.83  ? 255  TYR D CB  1 
ATOM   1945 C CG  . TYR A 1 255 ? 220.791 258.226 119.584 1.00 68.83  ? 255  TYR D CG  1 
ATOM   1946 C CD1 . TYR A 1 255 ? 221.912 257.920 118.824 1.00 68.83  ? 255  TYR D CD1 1 
ATOM   1947 C CD2 . TYR A 1 255 ? 220.719 259.483 120.169 1.00 68.83  ? 255  TYR D CD2 1 
ATOM   1948 C CE1 . TYR A 1 255 ? 222.930 258.837 118.651 1.00 68.83  ? 255  TYR D CE1 1 
ATOM   1949 C CE2 . TYR A 1 255 ? 221.734 260.407 120.002 1.00 68.83  ? 255  TYR D CE2 1 
ATOM   1950 C CZ  . TYR A 1 255 ? 222.837 260.078 119.243 1.00 68.83  ? 255  TYR D CZ  1 
ATOM   1951 O OH  . TYR A 1 255 ? 223.850 260.994 119.074 1.00 68.83  ? 255  TYR D OH  1 
ATOM   1952 N N   . ILE A 1 256 ? 216.576 256.211 119.364 1.00 65.50  ? 256  ILE D N   1 
ATOM   1953 C CA  . ILE A 1 256 ? 215.601 255.152 119.597 1.00 65.50  ? 256  ILE D CA  1 
ATOM   1954 C C   . ILE A 1 256 ? 214.294 255.539 118.919 1.00 65.50  ? 256  ILE D C   1 
ATOM   1955 O O   . ILE A 1 256 ? 213.825 256.674 119.061 1.00 65.50  ? 256  ILE D O   1 
ATOM   1956 C CB  . ILE A 1 256 ? 215.394 254.894 121.102 1.00 65.50  ? 256  ILE D CB  1 
ATOM   1957 C CG1 . ILE A 1 256 ? 214.207 253.955 121.335 1.00 65.50  ? 256  ILE D CG1 1 
ATOM   1958 C CG2 . ILE A 1 256 ? 215.220 256.204 121.858 1.00 65.50  ? 256  ILE D CG2 1 
ATOM   1959 C CD1 . ILE A 1 256 ? 214.407 252.567 120.767 1.00 65.50  ? 256  ILE D CD1 1 
ATOM   1960 N N   . SER A 1 257 ? 213.707 254.584 118.164 1.00 64.74  ? 257  SER D N   1 
ATOM   1961 C CA  . SER A 1 257 ? 212.457 254.762 117.443 1.00 64.74  ? 257  SER D CA  1 
ATOM   1962 C C   . SER A 1 257 ? 211.277 254.280 118.282 1.00 64.74  ? 257  SER D C   1 
ATOM   1963 O O   . SER A 1 257 ? 211.407 253.333 119.064 1.00 64.74  ? 257  SER D O   1 
ATOM   1964 C CB  . SER A 1 257 ? 212.491 253.996 116.123 1.00 64.74  ? 257  SER D CB  1 
ATOM   1965 O OG  . SER A 1 257 ? 212.664 252.608 116.345 1.00 64.74  ? 257  SER D OG  1 
ATOM   1966 N N   . PRO A 1 258 ? 210.110 254.916 118.138 1.00 63.91  ? 258  PRO D N   1 
ATOM   1967 C CA  . PRO A 1 258 ? 208.940 254.497 118.926 1.00 63.91  ? 258  PRO D CA  1 
ATOM   1968 C C   . PRO A 1 258 ? 208.336 253.177 118.477 1.00 63.91  ? 258  PRO D C   1 
ATOM   1969 O O   . PRO A 1 258 ? 207.473 252.643 119.186 1.00 63.91  ? 258  PRO D O   1 
ATOM   1970 C CB  . PRO A 1 258 ? 207.953 255.652 118.725 1.00 63.91  ? 258  PRO D CB  1 
ATOM   1971 C CG  . PRO A 1 258 ? 208.319 256.218 117.396 1.00 63.91  ? 258  PRO D CG  1 
ATOM   1972 C CD  . PRO A 1 258 ? 209.815 256.084 117.289 1.00 63.91  ? 258  PRO D CD  1 
ATOM   1973 N N   . ILE A 1 259 ? 208.750 252.638 117.334 1.00 63.53  ? 259  ILE D N   1 
ATOM   1974 C CA  . ILE A 1 259 ? 208.221 251.385 116.820 1.00 63.53  ? 259  ILE D CA  1 
ATOM   1975 C C   . ILE A 1 259 ? 209.213 250.242 116.992 1.00 63.53  ? 259  ILE D C   1 
ATOM   1976 O O   . ILE A 1 259 ? 208.826 249.132 117.367 1.00 63.53  ? 259  ILE D O   1 
ATOM   1977 C CB  . ILE A 1 259 ? 207.805 251.535 115.341 1.00 63.53  ? 259  ILE D CB  1 
ATOM   1978 C CG1 . ILE A 1 259 ? 206.794 252.672 115.184 1.00 63.53  ? 259  ILE D CG1 1 
ATOM   1979 C CG2 . ILE A 1 259 ? 207.226 250.233 114.811 1.00 63.53  ? 259  ILE D CG2 1 
ATOM   1980 C CD1 . ILE A 1 259 ? 205.521 252.470 115.975 1.00 63.53  ? 259  ILE D CD1 1 
ATOM   1981 N N   . GLY A 1 260 ? 210.491 250.493 116.735 1.00 65.01  ? 260  GLY D N   1 
ATOM   1982 C CA  . GLY A 1 260 ? 211.498 249.459 116.805 1.00 65.01  ? 260  GLY D CA  1 
ATOM   1983 C C   . GLY A 1 260 ? 211.827 249.062 118.234 1.00 65.01  ? 260  GLY D C   1 
ATOM   1984 O O   . GLY A 1 260 ? 211.220 249.507 119.209 1.00 65.01  ? 260  GLY D O   1 
ATOM   1985 N N   . CYS A 1 261 ? 212.827 248.194 118.345 1.00 66.29  ? 261  CYS D N   1 
ATOM   1986 C CA  . CYS A 1 261 ? 213.274 247.680 119.628 1.00 66.29  ? 261  CYS D CA  1 
ATOM   1987 C C   . CYS A 1 261 ? 214.318 248.607 120.247 1.00 66.29  ? 261  CYS D C   1 
ATOM   1988 O O   . CYS A 1 261 ? 214.843 249.519 119.605 1.00 66.29  ? 261  CYS D O   1 
ATOM   1989 C CB  . CYS A 1 261 ? 213.843 246.270 119.469 1.00 66.29  ? 261  CYS D CB  1 
ATOM   1990 S SG  . CYS A 1 261 ? 212.719 245.097 118.680 1.00 66.29  ? 261  CYS D SG  1 
ATOM   1991 N N   . LEU A 1 262 ? 214.617 248.358 121.519 1.00 63.26  ? 262  LEU D N   1 
ATOM   1992 C CA  . LEU A 1 262 ? 215.609 249.144 122.232 1.00 63.26  ? 262  LEU D CA  1 
ATOM   1993 C C   . LEU A 1 262 ? 217.021 248.717 121.835 1.00 63.26  ? 262  LEU D C   1 
ATOM   1994 O O   . LEU A 1 262 ? 217.270 247.538 121.570 1.00 63.26  ? 262  LEU D O   1 
ATOM   1995 C CB  . LEU A 1 262 ? 215.433 248.985 123.738 1.00 63.26  ? 262  LEU D CB  1 
ATOM   1996 C CG  . LEU A 1 262 ? 214.143 249.536 124.346 1.00 63.26  ? 262  LEU D CG  1 
ATOM   1997 C CD1 . LEU A 1 262 ? 214.068 249.203 125.827 1.00 63.26  ? 262  LEU D CD1 1 
ATOM   1998 C CD2 . LEU A 1 262 ? 214.053 251.036 124.128 1.00 63.26  ? 262  LEU D CD2 1 
ATOM   1999 N N   . PRO A 1 263 ? 217.960 249.658 121.780 1.00 65.21  ? 263  PRO D N   1 
ATOM   2000 C CA  . PRO A 1 263 ? 219.352 249.292 121.506 1.00 65.21  ? 263  PRO D CA  1 
ATOM   2001 C C   . PRO A 1 263 ? 219.952 248.498 122.657 1.00 65.21  ? 263  PRO D C   1 
ATOM   2002 O O   . PRO A 1 263 ? 219.467 248.520 123.790 1.00 65.21  ? 263  PRO D O   1 
ATOM   2003 C CB  . PRO A 1 263 ? 220.052 250.645 121.336 1.00 65.21  ? 263  PRO D CB  1 
ATOM   2004 C CG  . PRO A 1 263 ? 219.189 251.609 122.075 1.00 65.21  ? 263  PRO D CG  1 
ATOM   2005 C CD  . PRO A 1 263 ? 217.784 251.113 121.915 1.00 65.21  ? 263  PRO D CD  1 
ATOM   2006 N N   . ALA A 1 264 ? 221.036 247.786 122.343 1.00 65.10  ? 264  ALA D N   1 
ATOM   2007 C CA  . ALA A 1 264 ? 221.633 246.873 123.311 1.00 65.10  ? 264  ALA D CA  1 
ATOM   2008 C C   . ALA A 1 264 ? 222.458 247.595 124.369 1.00 65.10  ? 264  ALA D C   1 
ATOM   2009 O O   . ALA A 1 264 ? 222.547 247.118 125.505 1.00 65.10  ? 264  ALA D O   1 
ATOM   2010 C CB  . ALA A 1 264 ? 222.500 245.840 122.591 1.00 65.10  ? 264  ALA D CB  1 
ATOM   2011 N N   . HIS A 1 265 ? 223.063 248.731 124.027 1.00 68.75  ? 265  HIS D N   1 
ATOM   2012 C CA  . HIS A 1 265 ? 223.963 249.432 124.933 1.00 68.75  ? 265  HIS D CA  1 
ATOM   2013 C C   . HIS A 1 265 ? 223.280 250.556 125.702 1.00 68.75  ? 265  HIS D C   1 
ATOM   2014 O O   . HIS A 1 265 ? 223.966 251.359 126.341 1.00 68.75  ? 265  HIS D O   1 
ATOM   2015 C CB  . HIS A 1 265 ? 225.163 249.982 124.160 1.00 68.75  ? 265  HIS D CB  1 
ATOM   2016 C CG  . HIS A 1 265 ? 224.807 251.039 123.162 1.00 68.75  ? 265  HIS D CG  1 
ATOM   2017 N ND1 . HIS A 1 265 ? 224.217 250.750 121.951 1.00 68.75  ? 265  HIS D ND1 1 
ATOM   2018 C CD2 . HIS A 1 265 ? 224.962 252.383 123.194 1.00 68.75  ? 265  HIS D CD2 1 
ATOM   2019 C CE1 . HIS A 1 265 ? 224.021 251.871 121.281 1.00 68.75  ? 265  HIS D CE1 1 
ATOM   2020 N NE2 . HIS A 1 265 ? 224.465 252.877 122.013 1.00 68.75  ? 265  HIS D NE2 1 
ATOM   2021 N N   . LEU A 1 266 ? 221.953 250.632 125.660 1.00 66.92  ? 266  LEU D N   1 
ATOM   2022 C CA  . LEU A 1 266 ? 221.193 251.635 126.395 1.00 66.92  ? 266  LEU D CA  1 
ATOM   2023 C C   . LEU A 1 266 ? 220.215 250.978 127.361 1.00 66.92  ? 266  LEU D C   1 
ATOM   2024 O O   . LEU A 1 266 ? 219.060 251.392 127.484 1.00 66.92  ? 266  LEU D O   1 
ATOM   2025 C CB  . LEU A 1 266 ? 220.458 252.574 125.442 1.00 66.92  ? 266  LEU D CB  1 
ATOM   2026 C CG  . LEU A 1 266 ? 221.318 253.464 124.542 1.00 66.92  ? 266  LEU D CG  1 
ATOM   2027 C CD1 . LEU A 1 266 ? 220.455 254.489 123.826 1.00 66.92  ? 266  LEU D CD1 1 
ATOM   2028 C CD2 . LEU A 1 266 ? 222.411 254.149 125.345 1.00 66.92  ? 266  LEU D CD2 1 
ATOM   2029 N N   . LEU A 1 267 ? 220.669 249.940 128.063 1.00 64.39  ? 267  LEU D N   1 
ATOM   2030 C CA  . LEU A 1 267 ? 219.832 249.215 129.011 1.00 64.39  ? 267  LEU D CA  1 
ATOM   2031 C C   . LEU A 1 267 ? 220.356 249.295 130.439 1.00 64.39  ? 267  LEU D C   1 
ATOM   2032 O O   . LEU A 1 267 ? 219.847 248.585 131.315 1.00 64.39  ? 267  LEU D O   1 
ATOM   2033 C CB  . LEU A 1 267 ? 219.695 247.750 128.588 1.00 64.39  ? 267  LEU D CB  1 
ATOM   2034 C CG  . LEU A 1 267 ? 219.025 247.505 127.236 1.00 64.39  ? 267  LEU D CG  1 
ATOM   2035 C CD1 . LEU A 1 267 ? 218.958 246.017 126.937 1.00 64.39  ? 267  LEU D CD1 1 
ATOM   2036 C CD2 . LEU A 1 267 ? 217.637 248.125 127.206 1.00 64.39  ? 267  LEU D CD2 1 
ATOM   2037 N N   . GLY A 1 268 ? 221.354 250.135 130.700 1.00 64.54  ? 268  GLY D N   1 
ATOM   2038 C CA  . GLY A 1 268 ? 221.893 250.265 132.038 1.00 64.54  ? 268  GLY D CA  1 
ATOM   2039 C C   . GLY A 1 268 ? 222.734 249.103 132.510 1.00 64.54  ? 268  GLY D C   1 
ATOM   2040 O O   . GLY A 1 268 ? 223.125 249.075 133.681 1.00 64.54  ? 268  GLY D O   1 
ATOM   2041 N N   . ASP A 1 269 ? 223.026 248.141 131.639 1.00 66.40  ? 269  ASP D N   1 
ATOM   2042 C CA  . ASP A 1 269 ? 223.828 246.983 132.001 1.00 66.40  ? 269  ASP D CA  1 
ATOM   2043 C C   . ASP A 1 269 ? 224.748 246.638 130.839 1.00 66.40  ? 269  ASP D C   1 
ATOM   2044 O O   . ASP A 1 269 ? 224.483 246.987 129.686 1.00 66.40  ? 269  ASP D O   1 
ATOM   2045 C CB  . ASP A 1 269 ? 222.945 245.781 132.368 1.00 66.40  ? 269  ASP D CB  1 
ATOM   2046 C CG  . ASP A 1 269 ? 223.737 244.632 132.959 1.00 66.40  ? 269  ASP D CG  1 
ATOM   2047 O OD1 . ASP A 1 269 ? 224.228 244.771 134.099 1.00 66.40  ? 269  ASP D OD1 1 
ATOM   2048 O OD2 . ASP A 1 269 ? 223.869 243.590 132.283 1.00 66.40  ? 269  ASP D OD2 1 
ATOM   2049 N N   . MET A 1 270 ? 225.845 245.948 131.162 1.00 66.56  ? 270  MET D N   1 
ATOM   2050 C CA  . MET A 1 270 ? 226.797 245.546 130.131 1.00 66.56  ? 270  MET D CA  1 
ATOM   2051 C C   . MET A 1 270 ? 226.157 244.622 129.104 1.00 66.56  ? 270  MET D C   1 
ATOM   2052 O O   . MET A 1 270 ? 226.512 244.666 127.921 1.00 66.56  ? 270  MET D O   1 
ATOM   2053 C CB  . MET A 1 270 ? 228.008 244.869 130.776 1.00 66.56  ? 270  MET D CB  1 
ATOM   2054 C CG  . MET A 1 270 ? 229.121 244.481 129.810 1.00 66.56  ? 270  MET D CG  1 
ATOM   2055 S SD  . MET A 1 270 ? 230.120 245.875 129.246 1.00 66.56  ? 270  MET D SD  1 
ATOM   2056 C CE  . MET A 1 270 ? 229.329 246.273 127.690 1.00 66.56  ? 270  MET D CE  1 
ATOM   2057 N N   . TRP A 1 271 ? 225.208 243.787 129.530 1.00 62.01  ? 271  TRP D N   1 
ATOM   2058 C CA  . TRP A 1 271 ? 224.535 242.859 128.637 1.00 62.01  ? 271  TRP D CA  1 
ATOM   2059 C C   . TRP A 1 271 ? 223.030 243.060 128.566 1.00 62.01  ? 271  TRP D C   1 
ATOM   2060 O O   . TRP A 1 271 ? 222.376 242.404 127.747 1.00 62.01  ? 271  TRP D O   1 
ATOM   2061 C CB  . TRP A 1 271 ? 224.821 241.408 129.058 1.00 62.01  ? 271  TRP D CB  1 
ATOM   2062 C CG  . TRP A 1 271 ? 226.265 241.142 129.341 1.00 62.01  ? 271  TRP D CG  1 
ATOM   2063 C CD1 . TRP A 1 271 ? 227.221 240.766 128.445 1.00 62.01  ? 271  TRP D CD1 1 
ATOM   2064 C CD2 . TRP A 1 271 ? 226.919 241.233 130.612 1.00 62.01  ? 271  TRP D CD2 1 
ATOM   2065 N NE1 . TRP A 1 271 ? 228.431 240.616 129.078 1.00 62.01  ? 271  TRP D NE1 1 
ATOM   2066 C CE2 . TRP A 1 271 ? 228.272 240.897 130.410 1.00 62.01  ? 271  TRP D CE2 1 
ATOM   2067 C CE3 . TRP A 1 271 ? 226.492 241.564 131.902 1.00 62.01  ? 271  TRP D CE3 1 
ATOM   2068 C CZ2 . TRP A 1 271 ? 229.200 240.883 131.448 1.00 62.01  ? 271  TRP D CZ2 1 
ATOM   2069 C CZ3 . TRP A 1 271 ? 227.415 241.550 132.930 1.00 62.01  ? 271  TRP D CZ3 1 
ATOM   2070 C CH2 . TRP A 1 271 ? 228.753 241.212 132.698 1.00 62.01  ? 271  TRP D CH2 1 
ATOM   2071 N N   . GLY A 1 272 ? 222.462 243.938 129.389 1.00 58.33  ? 272  GLY D N   1 
ATOM   2072 C CA  . GLY A 1 272 ? 221.027 244.129 129.400 1.00 58.33  ? 272  GLY D CA  1 
ATOM   2073 C C   . GLY A 1 272 ? 220.268 243.148 130.259 1.00 58.33  ? 272  GLY D C   1 
ATOM   2074 O O   . GLY A 1 272 ? 219.067 242.955 130.048 1.00 58.33  ? 272  GLY D O   1 
ATOM   2075 N N   . ARG A 1 273 ? 220.934 242.515 131.227 1.00 54.98  ? 273  ARG D N   1 
ATOM   2076 C CA  . ARG A 1 273 ? 220.267 241.535 132.077 1.00 54.98  ? 273  ARG D CA  1 
ATOM   2077 C C   . ARG A 1 273 ? 219.300 242.215 133.039 1.00 54.98  ? 273  ARG D C   1 
ATOM   2078 O O   . ARG A 1 273 ? 218.090 241.963 133.007 1.00 54.98  ? 273  ARG D O   1 
ATOM   2079 C CB  . ARG A 1 273 ? 221.309 240.715 132.839 1.00 54.98  ? 273  ARG D CB  1 
ATOM   2080 C CG  . ARG A 1 273 ? 220.726 239.640 133.737 1.00 54.98  ? 273  ARG D CG  1 
ATOM   2081 C CD  . ARG A 1 273 ? 221.821 238.922 134.506 1.00 54.98  ? 273  ARG D CD  1 
ATOM   2082 N NE  . ARG A 1 273 ? 221.280 237.954 135.455 1.00 54.98  ? 273  ARG D NE  1 
ATOM   2083 C CZ  . ARG A 1 273 ? 222.011 237.298 136.350 1.00 54.98  ? 273  ARG D CZ  1 
ATOM   2084 N NH1 . ARG A 1 273 ? 221.435 236.436 137.175 1.00 54.98  ? 273  ARG D NH1 1 
ATOM   2085 N NH2 . ARG A 1 273 ? 223.318 237.508 136.423 1.00 54.98  ? 273  ARG D NH2 1 
ATOM   2086 N N   . PHE A 1 274 ? 219.816 243.085 133.902 1.00 54.31  ? 274  PHE D N   1 
ATOM   2087 C CA  . PHE A 1 274 ? 218.999 243.811 134.865 1.00 54.31  ? 274  PHE D CA  1 
ATOM   2088 C C   . PHE A 1 274 ? 218.789 245.241 134.385 1.00 54.31  ? 274  PHE D C   1 
ATOM   2089 O O   . PHE A 1 274 ? 219.743 245.912 133.979 1.00 54.31  ? 274  PHE D O   1 
ATOM   2090 C CB  . PHE A 1 274 ? 219.651 243.815 136.248 1.00 54.31  ? 274  PHE D CB  1 
ATOM   2091 C CG  . PHE A 1 274 ? 219.773 242.454 136.868 1.00 54.31  ? 274  PHE D CG  1 
ATOM   2092 C CD1 . PHE A 1 274 ? 218.657 241.800 137.361 1.00 54.31  ? 274  PHE D CD1 1 
ATOM   2093 C CD2 . PHE A 1 274 ? 221.007 241.833 136.971 1.00 54.31  ? 274  PHE D CD2 1 
ATOM   2094 C CE1 . PHE A 1 274 ? 218.767 240.549 137.936 1.00 54.31  ? 274  PHE D CE1 1 
ATOM   2095 C CE2 . PHE A 1 274 ? 221.123 240.583 137.547 1.00 54.31  ? 274  PHE D CE2 1 
ATOM   2096 C CZ  . PHE A 1 274 ? 220.001 239.940 138.029 1.00 54.31  ? 274  PHE D CZ  1 
ATOM   2097 N N   . TRP A 1 275 ? 217.539 245.701 134.434 1.00 55.23  ? 275  TRP D N   1 
ATOM   2098 C CA  . TRP A 1 275 ? 217.190 247.076 134.099 1.00 55.23  ? 275  TRP D CA  1 
ATOM   2099 C C   . TRP A 1 275 ? 217.120 247.967 135.334 1.00 55.23  ? 275  TRP D C   1 
ATOM   2100 O O   . TRP A 1 275 ? 216.396 248.968 135.339 1.00 55.23  ? 275  TRP D O   1 
ATOM   2101 C CB  . TRP A 1 275 ? 215.864 247.118 133.339 1.00 55.23  ? 275  TRP D CB  1 
ATOM   2102 C CG  . TRP A 1 275 ? 215.921 246.499 131.975 1.00 55.23  ? 275  TRP D CG  1 
ATOM   2103 C CD1 . TRP A 1 275 ? 216.993 245.888 131.395 1.00 55.23  ? 275  TRP D CD1 1 
ATOM   2104 C CD2 . TRP A 1 275 ? 214.857 246.436 131.017 1.00 55.23  ? 275  TRP D CD2 1 
ATOM   2105 N NE1 . TRP A 1 275 ? 216.663 245.446 130.137 1.00 55.23  ? 275  TRP D NE1 1 
ATOM   2106 C CE2 . TRP A 1 275 ? 215.357 245.771 129.881 1.00 55.23  ? 275  TRP D CE2 1 
ATOM   2107 C CE3 . TRP A 1 275 ? 213.531 246.878 131.011 1.00 55.23  ? 275  TRP D CE3 1 
ATOM   2108 C CZ2 . TRP A 1 275 ? 214.578 245.536 128.751 1.00 55.23  ? 275  TRP D CZ2 1 
ATOM   2109 C CZ3 . TRP A 1 275 ? 212.759 246.644 129.888 1.00 55.23  ? 275  TRP D CZ3 1 
ATOM   2110 C CH2 . TRP A 1 275 ? 213.285 245.980 128.774 1.00 55.23  ? 275  TRP D CH2 1 
ATOM   2111 N N   . THR A 1 276 ? 217.863 247.616 136.387 1.00 53.53  ? 276  THR D N   1 
ATOM   2112 C CA  . THR A 1 276 ? 217.806 248.383 137.627 1.00 53.53  ? 276  THR D CA  1 
ATOM   2113 C C   . THR A 1 276 ? 218.396 249.776 137.448 1.00 53.53  ? 276  THR D C   1 
ATOM   2114 O O   . THR A 1 276 ? 217.878 250.752 138.003 1.00 53.53  ? 276  THR D O   1 
ATOM   2115 C CB  . THR A 1 276 ? 218.537 247.631 138.741 1.00 53.53  ? 276  THR D CB  1 
ATOM   2116 O OG1 . THR A 1 276 ? 218.019 246.299 138.840 1.00 53.53  ? 276  THR D OG1 1 
ATOM   2117 C CG2 . THR A 1 276 ? 218.352 248.338 140.075 1.00 53.53  ? 276  THR D CG2 1 
ATOM   2118 N N   . ASN A 1 277 ? 219.474 249.891 136.669 1.00 55.67  ? 277  ASN D N   1 
ATOM   2119 C CA  . ASN A 1 277 ? 220.129 251.179 136.473 1.00 55.67  ? 277  ASN D CA  1 
ATOM   2120 C C   . ASN A 1 277 ? 219.308 252.141 135.624 1.00 55.67  ? 277  ASN D C   1 
ATOM   2121 O O   . ASN A 1 277 ? 219.695 253.308 135.496 1.00 55.67  ? 277  ASN D O   1 
ATOM   2122 C CB  . ASN A 1 277 ? 221.505 250.972 135.838 1.00 55.67  ? 277  ASN D CB  1 
ATOM   2123 C CG  . ASN A 1 277 ? 222.413 250.107 136.690 1.00 55.67  ? 277  ASN D CG  1 
ATOM   2124 O OD1 . ASN A 1 277 ? 222.485 248.892 136.505 1.00 55.67  ? 277  ASN D OD1 1 
ATOM   2125 N ND2 . ASN A 1 277 ? 223.108 250.729 137.633 1.00 55.67  ? 277  ASN D ND2 1 
ATOM   2126 N N   . LEU A 1 278 ? 218.199 251.689 135.045 1.00 54.67  ? 278  LEU D N   1 
ATOM   2127 C CA  . LEU A 1 278 ? 217.310 252.547 134.274 1.00 54.67  ? 278  LEU D CA  1 
ATOM   2128 C C   . LEU A 1 278 ? 216.213 253.172 135.126 1.00 54.67  ? 278  LEU D C   1 
ATOM   2129 O O   . LEU A 1 278 ? 215.292 253.785 134.577 1.00 54.67  ? 278  LEU D O   1 
ATOM   2130 C CB  . LEU A 1 278 ? 216.686 251.758 133.121 1.00 54.67  ? 278  LEU D CB  1 
ATOM   2131 C CG  . LEU A 1 278 ? 217.156 252.131 131.714 1.00 54.67  ? 278  LEU D CG  1 
ATOM   2132 C CD1 . LEU A 1 278 ? 218.672 252.106 131.631 1.00 54.67  ? 278  LEU D CD1 1 
ATOM   2133 C CD2 . LEU A 1 278 ? 216.546 251.197 130.682 1.00 54.67  ? 278  LEU D CD2 1 
ATOM   2134 N N   . TYR A 1 279 ? 216.290 253.031 136.452 1.00 52.60  ? 279  TYR D N   1 
ATOM   2135 C CA  . TYR A 1 279 ? 215.265 253.602 137.317 1.00 52.60  ? 279  TYR D CA  1 
ATOM   2136 C C   . TYR A 1 279 ? 215.351 255.122 137.369 1.00 52.60  ? 279  TYR D C   1 
ATOM   2137 O O   . TYR A 1 279 ? 214.322 255.794 137.503 1.00 52.60  ? 279  TYR D O   1 
ATOM   2138 C CB  . TYR A 1 279 ? 215.379 253.014 138.724 1.00 52.60  ? 279  TYR D CB  1 
ATOM   2139 C CG  . TYR A 1 279 ? 214.375 253.569 139.709 1.00 52.60  ? 279  TYR D CG  1 
ATOM   2140 C CD1 . TYR A 1 279 ? 213.056 253.137 139.702 1.00 52.60  ? 279  TYR D CD1 1 
ATOM   2141 C CD2 . TYR A 1 279 ? 214.749 254.518 140.650 1.00 52.60  ? 279  TYR D CD2 1 
ATOM   2142 C CE1 . TYR A 1 279 ? 212.136 253.639 140.601 1.00 52.60  ? 279  TYR D CE1 1 
ATOM   2143 C CE2 . TYR A 1 279 ? 213.836 255.026 141.554 1.00 52.60  ? 279  TYR D CE2 1 
ATOM   2144 C CZ  . TYR A 1 279 ? 212.531 254.583 141.525 1.00 52.60  ? 279  TYR D CZ  1 
ATOM   2145 O OH  . TYR A 1 279 ? 211.618 255.085 142.423 1.00 52.60  ? 279  TYR D OH  1 
ATOM   2146 N N   . SER A 1 280 ? 216.559 255.680 137.266 1.00 53.02  ? 280  SER D N   1 
ATOM   2147 C CA  . SER A 1 280 ? 216.717 257.128 137.307 1.00 53.02  ? 280  SER D CA  1 
ATOM   2148 C C   . SER A 1 280 ? 216.145 257.811 136.072 1.00 53.02  ? 280  SER D C   1 
ATOM   2149 O O   . SER A 1 280 ? 215.854 259.011 136.122 1.00 53.02  ? 280  SER D O   1 
ATOM   2150 C CB  . SER A 1 280 ? 218.194 257.492 137.467 1.00 53.02  ? 280  SER D CB  1 
ATOM   2151 O OG  . SER A 1 280 ? 218.972 256.943 136.419 1.00 53.02  ? 280  SER D OG  1 
ATOM   2152 N N   . LEU A 1 281 ? 215.977 257.081 134.971 1.00 54.77  ? 281  LEU D N   1 
ATOM   2153 C CA  . LEU A 1 281 ? 215.413 257.638 133.749 1.00 54.77  ? 281  LEU D CA  1 
ATOM   2154 C C   . LEU A 1 281 ? 213.944 257.296 133.555 1.00 54.77  ? 281  LEU D C   1 
ATOM   2155 O O   . LEU A 1 281 ? 213.212 258.084 132.947 1.00 54.77  ? 281  LEU D O   1 
ATOM   2156 C CB  . LEU A 1 281 ? 216.199 257.154 132.524 1.00 54.77  ? 281  LEU D CB  1 
ATOM   2157 C CG  . LEU A 1 281 ? 217.531 257.832 132.188 1.00 54.77  ? 281  LEU D CG  1 
ATOM   2158 C CD1 . LEU A 1 281 ? 218.625 257.454 133.176 1.00 54.77  ? 281  LEU D CD1 1 
ATOM   2159 C CD2 . LEU A 1 281 ? 217.950 257.491 130.767 1.00 54.77  ? 281  LEU D CD2 1 
ATOM   2160 N N   . THR A 1 282 ? 213.494 256.145 134.054 1.00 55.57  ? 282  THR D N   1 
ATOM   2161 C CA  . THR A 1 282 ? 212.121 255.690 133.879 1.00 55.57  ? 282  THR D CA  1 
ATOM   2162 C C   . THR A 1 282 ? 211.314 255.794 135.170 1.00 55.57  ? 282  THR D C   1 
ATOM   2163 O O   . THR A 1 282 ? 210.337 255.066 135.356 1.00 55.57  ? 282  THR D O   1 
ATOM   2164 C CB  . THR A 1 282 ? 212.096 254.255 133.357 1.00 55.57  ? 282  THR D CB  1 
ATOM   2165 O OG1 . THR A 1 282 ? 212.622 253.373 134.357 1.00 55.57  ? 282  THR D OG1 1 
ATOM   2166 C CG2 . THR A 1 282 ? 212.935 254.133 132.096 1.00 55.57  ? 282  THR D CG2 1 
ATOM   2167 N N   . VAL A 1 283 ? 211.708 256.690 136.065 1.00 55.23  ? 283  VAL D N   1 
ATOM   2168 C CA  . VAL A 1 283 ? 210.994 256.838 137.338 1.00 55.23  ? 283  VAL D CA  1 
ATOM   2169 C C   . VAL A 1 283 ? 209.615 257.434 137.075 1.00 55.23  ? 283  VAL D C   1 
ATOM   2170 O O   . VAL A 1 283 ? 209.506 258.455 136.371 1.00 55.23  ? 283  VAL D O   1 
ATOM   2171 C CB  . VAL A 1 283 ? 211.802 257.707 138.307 1.00 55.23  ? 283  VAL D CB  1 
ATOM   2172 C CG1 . VAL A 1 283 ? 212.332 258.951 137.605 1.00 55.23  ? 283  VAL D CG1 1 
ATOM   2173 C CG2 . VAL A 1 283 ? 210.957 258.086 139.515 1.00 55.23  ? 283  VAL D CG2 1 
ATOM   2174 N N   . PRO A 1 284 ? 208.538 256.829 137.585 1.00 56.81  ? 284  PRO D N   1 
ATOM   2175 C CA  . PRO A 1 284 ? 207.202 257.403 137.340 1.00 56.81  ? 284  PRO D CA  1 
ATOM   2176 C C   . PRO A 1 284 ? 207.023 258.785 137.946 1.00 56.81  ? 284  PRO D C   1 
ATOM   2177 O O   . PRO A 1 284 ? 206.665 259.732 137.235 1.00 56.81  ? 284  PRO D O   1 
ATOM   2178 C CB  . PRO A 1 284 ? 206.260 256.369 137.976 1.00 56.81  ? 284  PRO D CB  1 
ATOM   2179 C CG  . PRO A 1 284 ? 207.062 255.110 138.061 1.00 56.81  ? 284  PRO D CG  1 
ATOM   2180 C CD  . PRO A 1 284 ? 208.469 255.549 138.306 1.00 56.81  ? 284  PRO D CD  1 
ATOM   2181 N N   . PHE A 1 285 ? 207.267 258.927 139.247 1.00 60.34  ? 285  PHE D N   1 
ATOM   2182 C CA  . PHE A 1 285 ? 207.097 260.196 139.953 1.00 60.34  ? 285  PHE D CA  1 
ATOM   2183 C C   . PHE A 1 285 ? 208.409 260.522 140.661 1.00 60.34  ? 285  PHE D C   1 
ATOM   2184 O O   . PHE A 1 285 ? 208.684 259.997 141.744 1.00 60.34  ? 285  PHE D O   1 
ATOM   2185 C CB  . PHE A 1 285 ? 205.936 260.126 140.940 1.00 60.34  ? 285  PHE D CB  1 
ATOM   2186 C CG  . PHE A 1 285 ? 204.642 259.677 140.322 1.00 60.34  ? 285  PHE D CG  1 
ATOM   2187 C CD1 . PHE A 1 285 ? 203.815 260.583 139.680 1.00 60.34  ? 285  PHE D CD1 1 
ATOM   2188 C CD2 . PHE A 1 285 ? 204.252 258.350 140.386 1.00 60.34  ? 285  PHE D CD2 1 
ATOM   2189 C CE1 . PHE A 1 285 ? 202.623 260.172 139.112 1.00 60.34  ? 285  PHE D CE1 1 
ATOM   2190 C CE2 . PHE A 1 285 ? 203.062 257.934 139.820 1.00 60.34  ? 285  PHE D CE2 1 
ATOM   2191 C CZ  . PHE A 1 285 ? 202.247 258.846 139.182 1.00 60.34  ? 285  PHE D CZ  1 
ATOM   2192 N N   . GLY A 1 286 ? 209.214 261.386 140.049 1.00 64.06  ? 286  GLY D N   1 
ATOM   2193 C CA  . GLY A 1 286 ? 210.481 261.787 140.621 1.00 64.06  ? 286  GLY D CA  1 
ATOM   2194 C C   . GLY A 1 286 ? 210.403 262.793 141.743 1.00 64.06  ? 286  GLY D C   1 
ATOM   2195 O O   . GLY A 1 286 ? 211.432 263.119 142.341 1.00 64.06  ? 286  GLY D O   1 
ATOM   2196 N N   . GLN A 1 287 ? 209.209 263.300 142.054 1.00 70.91  ? 287  GLN D N   1 
ATOM   2197 C CA  . GLN A 1 287 ? 209.063 264.290 143.113 1.00 70.91  ? 287  GLN D CA  1 
ATOM   2198 C C   . GLN A 1 287 ? 208.984 263.665 144.499 1.00 70.91  ? 287  GLN D C   1 
ATOM   2199 O O   . GLN A 1 287 ? 209.153 264.378 145.494 1.00 70.91  ? 287  GLN D O   1 
ATOM   2200 C CB  . GLN A 1 287 ? 207.820 265.147 142.866 1.00 70.91  ? 287  GLN D CB  1 
ATOM   2201 C CG  . GLN A 1 287 ? 207.850 265.920 141.558 1.00 70.91  ? 287  GLN D CG  1 
ATOM   2202 C CD  . GLN A 1 287 ? 206.606 266.760 141.349 1.00 70.91  ? 287  GLN D CD  1 
ATOM   2203 O OE1 . GLN A 1 287 ? 206.469 267.447 140.337 1.00 70.91  ? 287  GLN D OE1 1 
ATOM   2204 N NE2 . GLN A 1 287 ? 205.689 266.710 142.309 1.00 70.91  ? 287  GLN D NE2 1 
ATOM   2205 N N   . LYS A 1 288 ? 208.733 262.360 144.589 1.00 68.82  ? 288  LYS D N   1 
ATOM   2206 C CA  . LYS A 1 288 ? 208.666 261.673 145.871 1.00 68.82  ? 288  LYS D CA  1 
ATOM   2207 C C   . LYS A 1 288 ? 209.806 260.672 145.966 1.00 68.82  ? 288  LYS D C   1 
ATOM   2208 O O   . LYS A 1 288 ? 209.896 259.765 145.126 1.00 68.82  ? 288  LYS D O   1 
ATOM   2209 C CB  . LYS A 1 288 ? 207.321 260.970 146.042 1.00 68.82  ? 288  LYS D CB  1 
ATOM   2210 C CG  . LYS A 1 288 ? 206.123 261.900 145.931 1.00 68.82  ? 288  LYS D CG  1 
ATOM   2211 C CD  . LYS A 1 288 ? 204.829 261.187 146.289 1.00 68.82  ? 288  LYS D CD  1 
ATOM   2212 C CE  . LYS A 1 288 ? 204.802 260.795 147.756 1.00 68.82  ? 288  LYS D CE  1 
ATOM   2213 N NZ  . LYS A 1 288 ? 204.910 261.982 148.649 1.00 68.82  ? 288  LYS D NZ  1 
ATOM   2214 N N   . PRO A 1 289 ? 210.689 260.791 146.953 1.00 66.94  ? 289  PRO D N   1 
ATOM   2215 C CA  . PRO A 1 289 ? 211.835 259.882 147.032 1.00 66.94  ? 289  PRO D CA  1 
ATOM   2216 C C   . PRO A 1 289 ? 211.421 258.486 147.470 1.00 66.94  ? 289  PRO D C   1 
ATOM   2217 O O   . PRO A 1 289 ? 210.381 258.276 148.098 1.00 66.94  ? 289  PRO D O   1 
ATOM   2218 C CB  . PRO A 1 289 ? 212.741 260.544 148.074 1.00 66.94  ? 289  PRO D CB  1 
ATOM   2219 C CG  . PRO A 1 289 ? 211.799 261.307 148.942 1.00 66.94  ? 289  PRO D CG  1 
ATOM   2220 C CD  . PRO A 1 289 ? 210.701 261.793 148.033 1.00 66.94  ? 289  PRO D CD  1 
ATOM   2221 N N   . ASN A 1 290 ? 212.267 257.520 147.121 1.00 65.67  ? 290  ASN D N   1 
ATOM   2222 C CA  . ASN A 1 290 ? 212.027 256.135 147.489 1.00 65.67  ? 290  ASN D CA  1 
ATOM   2223 C C   . ASN A 1 290 ? 212.202 255.947 148.995 1.00 65.67  ? 290  ASN D C   1 
ATOM   2224 O O   . ASN A 1 290 ? 212.812 256.767 149.687 1.00 65.67  ? 290  ASN D O   1 
ATOM   2225 C CB  . ASN A 1 290 ? 212.974 255.210 146.722 1.00 65.67  ? 290  ASN D CB  1 
ATOM   2226 C CG  . ASN A 1 290 ? 212.566 253.753 146.808 1.00 65.67  ? 290  ASN D CG  1 
ATOM   2227 O OD1 . ASN A 1 290 ? 211.415 253.435 147.104 1.00 65.67  ? 290  ASN D OD1 1 
ATOM   2228 N ND2 . ASN A 1 290 ? 213.512 252.858 146.549 1.00 65.67  ? 290  ASN D ND2 1 
ATOM   2229 N N   . ILE A 1 291 ? 211.650 254.847 149.502 1.00 65.24  ? 291  ILE D N   1 
ATOM   2230 C CA  . ILE A 1 291 ? 211.733 254.534 150.926 1.00 65.24  ? 291  ILE D CA  1 
ATOM   2231 C C   . ILE A 1 291 ? 213.188 254.219 151.259 1.00 65.24  ? 291  ILE D C   1 
ATOM   2232 O O   . ILE A 1 291 ? 213.716 253.179 150.857 1.00 65.24  ? 291  ILE D O   1 
ATOM   2233 C CB  . ILE A 1 291 ? 210.811 253.369 151.301 1.00 65.24  ? 291  ILE D CB  1 
ATOM   2234 C CG1 . ILE A 1 291 ? 209.378 253.659 150.856 1.00 65.24  ? 291  ILE D CG1 1 
ATOM   2235 C CG2 . ILE A 1 291 ? 210.861 253.115 152.800 1.00 65.24  ? 291  ILE D CG2 1 
ATOM   2236 C CD1 . ILE A 1 291 ? 208.790 254.904 151.474 1.00 65.24  ? 291  ILE D CD1 1 
ATOM   2237 N N   . ASP A 1 292 ? 213.838 255.117 151.997 1.00 63.93  ? 292  ASP D N   1 
ATOM   2238 C CA  . ASP A 1 292 ? 215.235 254.957 152.390 1.00 63.93  ? 292  ASP D CA  1 
ATOM   2239 C C   . ASP A 1 292 ? 215.342 255.242 153.881 1.00 63.93  ? 292  ASP D C   1 
ATOM   2240 O O   . ASP A 1 292 ? 215.213 256.395 154.307 1.00 63.93  ? 292  ASP D O   1 
ATOM   2241 C CB  . ASP A 1 292 ? 216.145 255.886 151.587 1.00 63.93  ? 292  ASP D CB  1 
ATOM   2242 C CG  . ASP A 1 292 ? 217.617 255.607 151.820 1.00 63.93  ? 292  ASP D CG  1 
ATOM   2243 O OD1 . ASP A 1 292 ? 217.939 254.591 152.472 1.00 63.93  ? 292  ASP D OD1 1 
ATOM   2244 O OD2 . ASP A 1 292 ? 218.455 256.405 151.351 1.00 63.93  ? 292  ASP D OD2 1 
ATOM   2245 N N   . VAL A 1 293 ? 215.577 254.198 154.669 1.00 61.23  ? 293  VAL D N   1 
ATOM   2246 C CA  . VAL A 1 293 ? 215.670 254.323 156.115 1.00 61.23  ? 293  VAL D CA  1 
ATOM   2247 C C   . VAL A 1 293 ? 217.126 254.347 156.585 1.00 61.23  ? 293  VAL D C   1 
ATOM   2248 O O   . VAL A 1 293 ? 217.401 254.086 157.754 1.00 61.23  ? 293  VAL D O   1 
ATOM   2249 C CB  . VAL A 1 293 ? 214.875 253.217 156.826 1.00 61.23  ? 293  VAL D CB  1 
ATOM   2250 C CG1 . VAL A 1 293 ? 213.393 253.348 156.514 1.00 61.23  ? 293  VAL D CG1 1 
ATOM   2251 C CG2 . VAL A 1 293 ? 215.391 251.848 156.414 1.00 61.23  ? 293  VAL D CG2 1 
ATOM   2252 N N   . THR A 1 294 ? 218.064 254.656 155.687 1.00 60.97  ? 294  THR D N   1 
ATOM   2253 C CA  . THR A 1 294 ? 219.472 254.696 156.070 1.00 60.97  ? 294  THR D CA  1 
ATOM   2254 C C   . THR A 1 294 ? 219.741 255.806 157.080 1.00 60.97  ? 294  THR D C   1 
ATOM   2255 O O   . THR A 1 294 ? 220.465 255.598 158.061 1.00 60.97  ? 294  THR D O   1 
ATOM   2256 C CB  . THR A 1 294 ? 220.349 254.875 154.831 1.00 60.97  ? 294  THR D CB  1 
ATOM   2257 O OG1 . THR A 1 294 ? 220.083 253.820 153.898 1.00 60.97  ? 294  THR D OG1 1 
ATOM   2258 C CG2 . THR A 1 294 ? 221.822 254.845 155.210 1.00 60.97  ? 294  THR D CG2 1 
ATOM   2259 N N   . ASP A 1 295 ? 219.165 256.989 156.860 1.00 63.14  ? 295  ASP D N   1 
ATOM   2260 C CA  . ASP A 1 295 ? 219.342 258.087 157.806 1.00 63.14  ? 295  ASP D CA  1 
ATOM   2261 C C   . ASP A 1 295 ? 218.688 257.764 159.144 1.00 63.14  ? 295  ASP D C   1 
ATOM   2262 O O   . ASP A 1 295 ? 219.283 257.982 160.208 1.00 63.14  ? 295  ASP D O   1 
ATOM   2263 C CB  . ASP A 1 295 ? 218.771 259.378 157.220 1.00 63.14  ? 295  ASP D CB  1 
ATOM   2264 C CG  . ASP A 1 295 ? 219.337 259.694 155.849 1.00 63.14  ? 295  ASP D CG  1 
ATOM   2265 O OD1 . ASP A 1 295 ? 220.480 259.280 155.567 1.00 63.14  ? 295  ASP D OD1 1 
ATOM   2266 O OD2 . ASP A 1 295 ? 218.637 260.356 155.054 1.00 63.14  ? 295  ASP D OD2 1 
ATOM   2267 N N   . ALA A 1 296 ? 217.460 257.242 159.109 1.00 60.92  ? 296  ALA D N   1 
ATOM   2268 C CA  . ALA A 1 296 ? 216.793 256.823 160.336 1.00 60.92  ? 296  ALA D CA  1 
ATOM   2269 C C   . ALA A 1 296 ? 217.515 255.666 161.009 1.00 60.92  ? 296  ALA D C   1 
ATOM   2270 O O   . ALA A 1 296 ? 217.333 255.450 162.212 1.00 60.92  ? 296  ALA D O   1 
ATOM   2271 C CB  . ALA A 1 296 ? 215.343 256.438 160.043 1.00 60.92  ? 296  ALA D CB  1 
ATOM   2272 N N   . MET A 1 297 ? 218.328 254.919 160.262 1.00 60.40  ? 297  MET D N   1 
ATOM   2273 C CA  . MET A 1 297 ? 219.111 253.845 160.857 1.00 60.40  ? 297  MET D CA  1 
ATOM   2274 C C   . MET A 1 297 ? 220.399 254.365 161.483 1.00 60.40  ? 297  MET D C   1 
ATOM   2275 O O   . MET A 1 297 ? 220.856 253.817 162.492 1.00 60.40  ? 297  MET D O   1 
ATOM   2276 C CB  . MET A 1 297 ? 219.425 252.781 159.804 1.00 60.40  ? 297  MET D CB  1 
ATOM   2277 C CG  . MET A 1 297 ? 219.907 251.458 160.371 1.00 60.40  ? 297  MET D CG  1 
ATOM   2278 S SD  . MET A 1 297 ? 220.256 250.239 159.090 1.00 60.40  ? 297  MET D SD  1 
ATOM   2279 C CE  . MET A 1 297 ? 218.661 250.128 158.285 1.00 60.40  ? 297  MET D CE  1 
ATOM   2280 N N   . VAL A 1 298 ? 220.992 255.416 160.910 1.00 61.42  ? 298  VAL D N   1 
ATOM   2281 C CA  . VAL A 1 298 ? 222.227 255.953 161.473 1.00 61.42  ? 298  VAL D CA  1 
ATOM   2282 C C   . VAL A 1 298 ? 221.970 256.922 162.621 1.00 61.42  ? 298  VAL D C   1 
ATOM   2283 O O   . VAL A 1 298 ? 222.859 257.115 163.460 1.00 61.42  ? 298  VAL D O   1 
ATOM   2284 C CB  . VAL A 1 298 ? 223.091 256.646 160.403 1.00 61.42  ? 298  VAL D CB  1 
ATOM   2285 C CG1 . VAL A 1 298 ? 223.436 255.679 159.283 1.00 61.42  ? 298  VAL D CG1 1 
ATOM   2286 C CG2 . VAL A 1 298 ? 222.399 257.883 159.858 1.00 61.42  ? 298  VAL D CG2 1 
ATOM   2287 N N   . ASP A 1 299 ? 220.787 257.540 162.694 1.00 64.07  ? 299  ASP D N   1 
ATOM   2288 C CA  . ASP A 1 299 ? 220.521 258.425 163.824 1.00 64.07  ? 299  ASP D CA  1 
ATOM   2289 C C   . ASP A 1 299 ? 220.067 257.671 165.068 1.00 64.07  ? 299  ASP D C   1 
ATOM   2290 O O   . ASP A 1 299 ? 220.136 258.225 166.170 1.00 64.07  ? 299  ASP D O   1 
ATOM   2291 C CB  . ASP A 1 299 ? 219.485 259.496 163.455 1.00 64.07  ? 299  ASP D CB  1 
ATOM   2292 C CG  . ASP A 1 299 ? 218.188 258.915 162.918 1.00 64.07  ? 299  ASP D CG  1 
ATOM   2293 O OD1 . ASP A 1 299 ? 217.652 257.957 163.513 1.00 64.07  ? 299  ASP D OD1 1 
ATOM   2294 O OD2 . ASP A 1 299 ? 217.685 259.447 161.906 1.00 64.07  ? 299  ASP D OD2 1 
ATOM   2295 N N   . GLN A 1 300 ? 219.607 256.430 164.920 1.00 59.82  ? 300  GLN D N   1 
ATOM   2296 C CA  . GLN A 1 300 ? 219.223 255.602 166.055 1.00 59.82  ? 300  GLN D CA  1 
ATOM   2297 C C   . GLN A 1 300 ? 220.371 254.743 166.572 1.00 59.82  ? 300  GLN D C   1 
ATOM   2298 O O   . GLN A 1 300 ? 220.141 253.870 167.416 1.00 59.82  ? 300  GLN D O   1 
ATOM   2299 C CB  . GLN A 1 300 ? 218.035 254.710 165.683 1.00 59.82  ? 300  GLN D CB  1 
ATOM   2300 C CG  . GLN A 1 300 ? 216.742 255.468 165.430 1.00 59.82  ? 300  GLN D CG  1 
ATOM   2301 C CD  . GLN A 1 300 ? 215.568 254.545 165.169 1.00 59.82  ? 300  GLN D CD  1 
ATOM   2302 O OE1 . GLN A 1 300 ? 215.682 253.326 165.292 1.00 59.82  ? 300  GLN D OE1 1 
ATOM   2303 N NE2 . GLN A 1 300 ? 214.430 255.125 164.805 1.00 59.82  ? 300  GLN D NE2 1 
ATOM   2304 N N   . ALA A 1 301 ? 221.592 254.972 166.084 1.00 60.50  ? 301  ALA D N   1 
ATOM   2305 C CA  . ALA A 1 301 ? 222.789 254.255 166.526 1.00 60.50  ? 301  ALA D CA  1 
ATOM   2306 C C   . ALA A 1 301 ? 222.633 252.745 166.334 1.00 60.50  ? 301  ALA D C   1 
ATOM   2307 O O   . ALA A 1 301 ? 222.661 251.959 167.283 1.00 60.50  ? 301  ALA D O   1 
ATOM   2308 C CB  . ALA A 1 301 ? 223.127 254.599 167.981 1.00 60.50  ? 301  ALA D CB  1 
ATOM   2309 N N   . TRP A 1 302 ? 222.466 252.352 165.077 1.00 60.07  ? 302  TRP D N   1 
ATOM   2310 C CA  . TRP A 1 302 ? 222.350 250.948 164.719 1.00 60.07  ? 302  TRP D CA  1 
ATOM   2311 C C   . TRP A 1 302 ? 223.718 250.360 164.391 1.00 60.07  ? 302  TRP D C   1 
ATOM   2312 O O   . TRP A 1 302 ? 224.698 251.075 164.172 1.00 60.07  ? 302  TRP D O   1 
ATOM   2313 C CB  . TRP A 1 302 ? 221.404 250.769 163.531 1.00 60.07  ? 302  TRP D CB  1 
ATOM   2314 C CG  . TRP A 1 302 ? 219.959 250.709 163.915 1.00 60.07  ? 302  TRP D CG  1 
ATOM   2315 C CD1 . TRP A 1 302 ? 219.261 251.640 164.627 1.00 60.07  ? 302  TRP D CD1 1 
ATOM   2316 C CD2 . TRP A 1 302 ? 219.028 249.667 163.596 1.00 60.07  ? 302  TRP D CD2 1 
ATOM   2317 N NE1 . TRP A 1 302 ? 217.955 251.239 164.778 1.00 60.07  ? 302  TRP D NE1 1 
ATOM   2318 C CE2 . TRP A 1 302 ? 217.787 250.031 164.153 1.00 60.07  ? 302  TRP D CE2 1 
ATOM   2319 C CE3 . TRP A 1 302 ? 219.126 248.462 162.895 1.00 60.07  ? 302  TRP D CE3 1 
ATOM   2320 C CZ2 . TRP A 1 302 ? 216.652 249.233 164.032 1.00 60.07  ? 302  TRP D CZ2 1 
ATOM   2321 C CZ3 . TRP A 1 302 ? 217.998 247.670 162.777 1.00 60.07  ? 302  TRP D CZ3 1 
ATOM   2322 C CH2 . TRP A 1 302 ? 216.777 248.059 163.342 1.00 60.07  ? 302  TRP D CH2 1 
ATOM   2323 N N   . ASP A 1 303 ? 223.768 249.031 164.357 1.00 61.87  ? 303  ASP D N   1 
ATOM   2324 C CA  . ASP A 1 303 ? 224.999 248.310 164.074 1.00 61.87  ? 303  ASP D CA  1 
ATOM   2325 C C   . ASP A 1 303 ? 224.640 247.013 163.364 1.00 61.87  ? 303  ASP D C   1 
ATOM   2326 O O   . ASP A 1 303 ? 223.475 246.609 163.320 1.00 61.87  ? 303  ASP D O   1 
ATOM   2327 C CB  . ASP A 1 303 ? 225.792 248.044 165.360 1.00 61.87  ? 303  ASP D CB  1 
ATOM   2328 C CG  . ASP A 1 303 ? 227.227 247.633 165.091 1.00 61.87  ? 303  ASP D CG  1 
ATOM   2329 O OD1 . ASP A 1 303 ? 227.627 247.601 163.908 1.00 61.87  ? 303  ASP D OD1 1 
ATOM   2330 O OD2 . ASP A 1 303 ? 227.954 247.341 166.064 1.00 61.87  ? 303  ASP D OD2 1 
ATOM   2331 N N   . ALA A 1 304 ? 225.659 246.365 162.794 1.00 59.23  ? 304  ALA D N   1 
ATOM   2332 C CA  . ALA A 1 304 ? 225.443 245.076 162.143 1.00 59.23  ? 304  ALA D CA  1 
ATOM   2333 C C   . ALA A 1 304 ? 224.885 244.054 163.124 1.00 59.23  ? 304  ALA D C   1 
ATOM   2334 O O   . ALA A 1 304 ? 224.027 243.237 162.765 1.00 59.23  ? 304  ALA D O   1 
ATOM   2335 C CB  . ALA A 1 304 ? 226.747 244.574 161.524 1.00 59.23  ? 304  ALA D CB  1 
ATOM   2336 N N   . GLN A 1 305 ? 225.365 244.084 164.370 1.00 57.82  ? 305  GLN D N   1 
ATOM   2337 C CA  . GLN A 1 305 ? 224.808 243.216 165.401 1.00 57.82  ? 305  GLN D CA  1 
ATOM   2338 C C   . GLN A 1 305 ? 223.320 243.478 165.589 1.00 57.82  ? 305  GLN D C   1 
ATOM   2339 O O   . GLN A 1 305 ? 222.524 242.538 165.687 1.00 57.82  ? 305  GLN D O   1 
ATOM   2340 C CB  . GLN A 1 305 ? 225.561 243.418 166.716 1.00 57.82  ? 305  GLN D CB  1 
ATOM   2341 C CG  . GLN A 1 305 ? 225.226 242.406 167.799 1.00 57.82  ? 305  GLN D CG  1 
ATOM   2342 C CD  . GLN A 1 305 ? 225.904 241.068 167.579 1.00 57.82  ? 305  GLN D CD  1 
ATOM   2343 O OE1 . GLN A 1 305 ? 226.725 240.915 166.675 1.00 57.82  ? 305  GLN D OE1 1 
ATOM   2344 N NE2 . GLN A 1 305 ? 225.565 240.090 168.410 1.00 57.82  ? 305  GLN D NE2 1 
ATOM   2345 N N   . ARG A 1 306 ? 222.924 244.753 165.621 1.00 57.65  ? 306  ARG D N   1 
ATOM   2346 C CA  . ARG A 1 306 ? 221.511 245.092 165.751 1.00 57.65  ? 306  ARG D CA  1 
ATOM   2347 C C   . ARG A 1 306 ? 220.719 244.645 164.528 1.00 57.65  ? 306  ARG D C   1 
ATOM   2348 O O   . ARG A 1 306 ? 219.577 244.189 164.655 1.00 57.65  ? 306  ARG D O   1 
ATOM   2349 C CB  . ARG A 1 306 ? 221.354 246.596 165.974 1.00 57.65  ? 306  ARG D CB  1 
ATOM   2350 C CG  . ARG A 1 306 ? 219.913 247.070 166.062 1.00 57.65  ? 306  ARG D CG  1 
ATOM   2351 C CD  . ARG A 1 306 ? 219.210 246.499 167.280 1.00 57.65  ? 306  ARG D CD  1 
ATOM   2352 N NE  . ARG A 1 306 ? 217.814 246.921 167.348 1.00 57.65  ? 306  ARG D NE  1 
ATOM   2353 C CZ  . ARG A 1 306 ? 217.405 248.063 167.891 1.00 57.65  ? 306  ARG D CZ  1 
ATOM   2354 N NH1 . ARG A 1 306 ? 216.114 248.365 167.909 1.00 57.65  ? 306  ARG D NH1 1 
ATOM   2355 N NH2 . ARG A 1 306 ? 218.286 248.904 168.415 1.00 57.65  ? 306  ARG D NH2 1 
ATOM   2356 N N   . ILE A 1 307 ? 221.311 244.758 163.337 1.00 56.06  ? 307  ILE D N   1 
ATOM   2357 C CA  . ILE A 1 307 ? 220.626 244.336 162.117 1.00 56.06  ? 307  ILE D CA  1 
ATOM   2358 C C   . ILE A 1 307 ? 220.346 242.838 162.156 1.00 56.06  ? 307  ILE D C   1 
ATOM   2359 O O   . ILE A 1 307 ? 219.226 242.386 161.881 1.00 56.06  ? 307  ILE D O   1 
ATOM   2360 C CB  . ILE A 1 307 ? 221.452 244.723 160.877 1.00 56.06  ? 307  ILE D CB  1 
ATOM   2361 C CG1 . ILE A 1 307 ? 221.503 246.244 160.721 1.00 56.06  ? 307  ILE D CG1 1 
ATOM   2362 C CG2 . ILE A 1 307 ? 220.884 244.069 159.627 1.00 56.06  ? 307  ILE D CG2 1 
ATOM   2363 C CD1 . ILE A 1 307 ? 222.306 246.707 159.526 1.00 56.06  ? 307  ILE D CD1 1 
ATOM   2364 N N   . PHE A 1 308 ? 221.360 242.045 162.507 1.00 55.25  ? 308  PHE D N   1 
ATOM   2365 C CA  . PHE A 1 308 ? 221.162 240.601 162.559 1.00 55.25  ? 308  PHE D CA  1 
ATOM   2366 C C   . PHE A 1 308 ? 220.255 240.195 163.715 1.00 55.25  ? 308  PHE D C   1 
ATOM   2367 O O   . PHE A 1 308 ? 219.509 239.217 163.596 1.00 55.25  ? 308  PHE D O   1 
ATOM   2368 C CB  . PHE A 1 308 ? 222.511 239.888 162.640 1.00 55.25  ? 308  PHE D CB  1 
ATOM   2369 C CG  . PHE A 1 308 ? 223.217 239.788 161.317 1.00 55.25  ? 308  PHE D CG  1 
ATOM   2370 C CD1 . PHE A 1 308 ? 222.989 238.711 160.477 1.00 55.25  ? 308  PHE D CD1 1 
ATOM   2371 C CD2 . PHE A 1 308 ? 224.096 240.775 160.907 1.00 55.25  ? 308  PHE D CD2 1 
ATOM   2372 C CE1 . PHE A 1 308 ? 223.631 238.617 159.257 1.00 55.25  ? 308  PHE D CE1 1 
ATOM   2373 C CE2 . PHE A 1 308 ? 224.741 240.687 159.689 1.00 55.25  ? 308  PHE D CE2 1 
ATOM   2374 C CZ  . PHE A 1 308 ? 224.508 239.607 158.863 1.00 55.25  ? 308  PHE D CZ  1 
ATOM   2375 N N   . LYS A 1 309 ? 220.278 240.940 164.824 1.00 55.40  ? 309  LYS D N   1 
ATOM   2376 C CA  . LYS A 1 309 ? 219.338 240.670 165.907 1.00 55.40  ? 309  LYS D CA  1 
ATOM   2377 C C   . LYS A 1 309 ? 217.903 240.933 165.468 1.00 55.40  ? 309  LYS D C   1 
ATOM   2378 O O   . LYS A 1 309 ? 216.996 240.160 165.798 1.00 55.40  ? 309  LYS D O   1 
ATOM   2379 C CB  . LYS A 1 309 ? 219.687 241.514 167.132 1.00 55.40  ? 309  LYS D CB  1 
ATOM   2380 C CG  . LYS A 1 309 ? 220.810 240.948 167.985 1.00 55.40  ? 309  LYS D CG  1 
ATOM   2381 C CD  . LYS A 1 309 ? 220.405 239.626 168.616 1.00 55.40  ? 309  LYS D CD  1 
ATOM   2382 C CE  . LYS A 1 309 ? 221.454 239.137 169.600 1.00 55.40  ? 309  LYS D CE  1 
ATOM   2383 N NZ  . LYS A 1 309 ? 222.776 238.932 168.949 1.00 55.40  ? 309  LYS D NZ  1 
ATOM   2384 N N   . GLU A 1 310 ? 217.677 242.013 164.718 1.00 56.78  ? 310  GLU D N   1 
ATOM   2385 C CA  . GLU A 1 310 ? 216.335 242.298 164.219 1.00 56.78  ? 310  GLU D CA  1 
ATOM   2386 C C   . GLU A 1 310 ? 215.892 241.248 163.207 1.00 56.78  ? 310  GLU D C   1 
ATOM   2387 O O   . GLU A 1 310 ? 214.719 240.857 163.180 1.00 56.78  ? 310  GLU D O   1 
ATOM   2388 C CB  . GLU A 1 310 ? 216.292 243.695 163.602 1.00 56.78  ? 310  GLU D CB  1 
ATOM   2389 C CG  . GLU A 1 310 ? 214.889 244.214 163.339 1.00 56.78  ? 310  GLU D CG  1 
ATOM   2390 C CD  . GLU A 1 310 ? 214.136 244.530 164.617 1.00 56.78  ? 310  GLU D CD  1 
ATOM   2391 O OE1 . GLU A 1 310 ? 214.792 244.767 165.653 1.00 56.78  ? 310  GLU D OE1 1 
ATOM   2392 O OE2 . GLU A 1 310 ? 212.888 244.541 164.585 1.00 56.78  ? 310  GLU D OE2 1 
ATOM   2393 N N   . ALA A 1 311 ? 216.820 240.774 162.373 1.00 54.70  ? 311  ALA D N   1 
ATOM   2394 C CA  . ALA A 1 311 ? 216.489 239.701 161.441 1.00 54.70  ? 311  ALA D CA  1 
ATOM   2395 C C   . ALA A 1 311 ? 216.113 238.422 162.183 1.00 54.70  ? 311  ALA D C   1 
ATOM   2396 O O   . ALA A 1 311 ? 215.141 237.746 161.823 1.00 54.70  ? 311  ALA D O   1 
ATOM   2397 C CB  . ALA A 1 311 ? 217.658 239.451 160.489 1.00 54.70  ? 311  ALA D CB  1 
ATOM   2398 N N   . GLU A 1 312 ? 216.871 238.076 163.228 1.00 55.61  ? 312  GLU D N   1 
ATOM   2399 C CA  . GLU A 1 312 ? 216.541 236.900 164.026 1.00 55.61  ? 312  GLU D CA  1 
ATOM   2400 C C   . GLU A 1 312 ? 215.197 237.068 164.723 1.00 55.61  ? 312  GLU D C   1 
ATOM   2401 O O   . GLU A 1 312 ? 214.433 236.105 164.854 1.00 55.61  ? 312  GLU D O   1 
ATOM   2402 C CB  . GLU A 1 312 ? 217.643 236.630 165.049 1.00 55.61  ? 312  GLU D CB  1 
ATOM   2403 C CG  . GLU A 1 312 ? 217.423 235.372 165.874 1.00 55.61  ? 312  GLU D CG  1 
ATOM   2404 C CD  . GLU A 1 312 ? 218.420 235.233 167.006 1.00 55.61  ? 312  GLU D CD  1 
ATOM   2405 O OE1 . GLU A 1 312 ? 219.049 236.247 167.373 1.00 55.61  ? 312  GLU D OE1 1 
ATOM   2406 O OE2 . GLU A 1 312 ? 218.574 234.110 167.529 1.00 55.61  ? 312  GLU D OE2 1 
ATOM   2407 N N   . LYS A 1 313 ? 214.893 238.285 165.181 1.00 55.62  ? 313  LYS D N   1 
ATOM   2408 C CA  . LYS A 1 313 ? 213.593 238.546 165.789 1.00 55.62  ? 313  LYS D CA  1 
ATOM   2409 C C   . LYS A 1 313 ? 212.469 238.343 164.783 1.00 55.62  ? 313  LYS D C   1 
ATOM   2410 O O   . LYS A 1 313 ? 211.435 237.747 165.105 1.00 55.62  ? 313  LYS D O   1 
ATOM   2411 C CB  . LYS A 1 313 ? 213.558 239.964 166.358 1.00 55.62  ? 313  LYS D CB  1 
ATOM   2412 C CG  . LYS A 1 313 ? 212.253 240.329 167.045 1.00 55.62  ? 313  LYS D CG  1 
ATOM   2413 C CD  . LYS A 1 313 ? 212.260 241.779 167.501 1.00 55.62  ? 313  LYS D CD  1 
ATOM   2414 C CE  . LYS A 1 313 ? 213.417 242.056 168.445 1.00 55.62  ? 313  LYS D CE  1 
ATOM   2415 N NZ  . LYS A 1 313 ? 213.355 241.205 169.665 1.00 55.62  ? 313  LYS D NZ  1 
ATOM   2416 N N   . PHE A 1 314 ? 212.657 238.828 163.555 1.00 54.98  ? 314  PHE D N   1 
ATOM   2417 C CA  . PHE A 1 314 ? 211.672 238.596 162.503 1.00 54.98  ? 314  PHE D CA  1 
ATOM   2418 C C   . PHE A 1 314 ? 211.473 237.105 162.258 1.00 54.98  ? 314  PHE D C   1 
ATOM   2419 O O   . PHE A 1 314 ? 210.337 236.620 162.175 1.00 54.98  ? 314  PHE D O   1 
ATOM   2420 C CB  . PHE A 1 314 ? 212.106 239.304 161.218 1.00 54.98  ? 314  PHE D CB  1 
ATOM   2421 C CG  . PHE A 1 314 ? 211.346 238.869 159.996 1.00 54.98  ? 314  PHE D CG  1 
ATOM   2422 C CD1 . PHE A 1 314 ? 211.918 238.001 159.080 1.00 54.98  ? 314  PHE D CD1 1 
ATOM   2423 C CD2 . PHE A 1 314 ? 210.060 239.327 159.763 1.00 54.98  ? 314  PHE D CD2 1 
ATOM   2424 C CE1 . PHE A 1 314 ? 211.223 237.600 157.956 1.00 54.98  ? 314  PHE D CE1 1 
ATOM   2425 C CE2 . PHE A 1 314 ? 209.360 238.928 158.640 1.00 54.98  ? 314  PHE D CE2 1 
ATOM   2426 C CZ  . PHE A 1 314 ? 209.942 238.063 157.736 1.00 54.98  ? 314  PHE D CZ  1 
ATOM   2427 N N   . PHE A 1 315 ? 212.574 236.357 162.152 1.00 53.98  ? 315  PHE D N   1 
ATOM   2428 C CA  . PHE A 1 315 ? 212.468 234.933 161.843 1.00 53.98  ? 315  PHE D CA  1 
ATOM   2429 C C   . PHE A 1 315 ? 211.818 234.155 162.982 1.00 53.98  ? 315  PHE D C   1 
ATOM   2430 O O   . PHE A 1 315 ? 211.062 233.207 162.737 1.00 53.98  ? 315  PHE D O   1 
ATOM   2431 C CB  . PHE A 1 315 ? 213.844 234.359 161.511 1.00 53.98  ? 315  PHE D CB  1 
ATOM   2432 C CG  . PHE A 1 315 ? 214.245 234.552 160.079 1.00 53.98  ? 315  PHE D CG  1 
ATOM   2433 C CD1 . PHE A 1 315 ? 213.784 233.692 159.097 1.00 53.98  ? 315  PHE D CD1 1 
ATOM   2434 C CD2 . PHE A 1 315 ? 215.075 235.595 159.711 1.00 53.98  ? 315  PHE D CD2 1 
ATOM   2435 C CE1 . PHE A 1 315 ? 214.147 233.869 157.779 1.00 53.98  ? 315  PHE D CE1 1 
ATOM   2436 C CE2 . PHE A 1 315 ? 215.440 235.778 158.395 1.00 53.98  ? 315  PHE D CE2 1 
ATOM   2437 C CZ  . PHE A 1 315 ? 214.978 234.914 157.429 1.00 53.98  ? 315  PHE D CZ  1 
ATOM   2438 N N   . VAL A 1 316 ? 212.094 234.533 164.232 1.00 55.23  ? 316  VAL D N   1 
ATOM   2439 C CA  . VAL A 1 316 ? 211.466 233.844 165.354 1.00 55.23  ? 316  VAL D CA  1 
ATOM   2440 C C   . VAL A 1 316 ? 210.016 234.276 165.535 1.00 55.23  ? 316  VAL D C   1 
ATOM   2441 O O   . VAL A 1 316 ? 209.218 233.519 166.102 1.00 55.23  ? 316  VAL D O   1 
ATOM   2442 C CB  . VAL A 1 316 ? 212.268 234.056 166.652 1.00 55.23  ? 316  VAL D CB  1 
ATOM   2443 C CG1 . VAL A 1 316 ? 212.072 235.461 167.194 1.00 55.23  ? 316  VAL D CG1 1 
ATOM   2444 C CG2 . VAL A 1 316 ? 211.885 233.013 167.695 1.00 55.23  ? 316  VAL D CG2 1 
ATOM   2445 N N   . SER A 1 317 ? 209.645 235.466 165.057 1.00 56.47  ? 317  SER D N   1 
ATOM   2446 C CA  . SER A 1 317 ? 208.239 235.848 165.051 1.00 56.47  ? 317  SER D CA  1 
ATOM   2447 C C   . SER A 1 317 ? 207.468 235.125 163.957 1.00 56.47  ? 317  SER D C   1 
ATOM   2448 O O   . SER A 1 317 ? 206.270 234.864 164.118 1.00 56.47  ? 317  SER D O   1 
ATOM   2449 C CB  . SER A 1 317 ? 208.101 237.361 164.879 1.00 56.47  ? 317  SER D CB  1 
ATOM   2450 O OG  . SER A 1 317 ? 208.620 237.781 163.630 1.00 56.47  ? 317  SER D OG  1 
ATOM   2451 N N   . VAL A 1 318 ? 208.129 234.804 162.842 1.00 56.40  ? 318  VAL D N   1 
ATOM   2452 C CA  . VAL A 1 318 ? 207.474 234.026 161.792 1.00 56.40  ? 318  VAL D CA  1 
ATOM   2453 C C   . VAL A 1 318 ? 207.135 232.629 162.300 1.00 56.40  ? 318  VAL D C   1 
ATOM   2454 O O   . VAL A 1 318 ? 206.072 232.079 161.987 1.00 56.40  ? 318  VAL D O   1 
ATOM   2455 C CB  . VAL A 1 318 ? 208.357 233.977 160.531 1.00 56.40  ? 318  VAL D CB  1 
ATOM   2456 C CG1 . VAL A 1 318 ? 207.778 233.013 159.509 1.00 56.40  ? 318  VAL D CG1 1 
ATOM   2457 C CG2 . VAL A 1 318 ? 208.490 235.364 159.926 1.00 56.40  ? 318  VAL D CG2 1 
ATOM   2458 N N   . GLY A 1 319 ? 208.020 232.041 163.100 1.00 53.09  ? 319  GLY D N   1 
ATOM   2459 C CA  . GLY A 1 319 ? 207.775 230.723 163.654 1.00 53.09  ? 319  GLY D CA  1 
ATOM   2460 C C   . GLY A 1 319 ? 208.951 229.780 163.507 1.00 53.09  ? 319  GLY D C   1 
ATOM   2461 O O   . GLY A 1 319 ? 208.826 228.577 163.751 1.00 53.09  ? 319  GLY D O   1 
ATOM   2462 N N   . LEU A 1 320 ? 210.100 230.318 163.107 1.00 54.61  ? 320  LEU D N   1 
ATOM   2463 C CA  . LEU A 1 320 ? 211.319 229.558 162.891 1.00 54.61  ? 320  LEU D CA  1 
ATOM   2464 C C   . LEU A 1 320 ? 212.229 229.642 164.113 1.00 54.61  ? 320  LEU D C   1 
ATOM   2465 O O   . LEU A 1 320 ? 212.168 230.612 164.874 1.00 54.61  ? 320  LEU D O   1 
ATOM   2466 C CB  . LEU A 1 320 ? 212.066 230.073 161.655 1.00 54.61  ? 320  LEU D CB  1 
ATOM   2467 C CG  . LEU A 1 320 ? 211.566 229.610 160.281 1.00 54.61  ? 320  LEU D CG  1 
ATOM   2468 C CD1 . LEU A 1 320 ? 210.209 230.204 159.930 1.00 54.61  ? 320  LEU D CD1 1 
ATOM   2469 C CD2 . LEU A 1 320 ? 212.584 229.941 159.203 1.00 54.61  ? 320  LEU D CD2 1 
ATOM   2470 N N   . PRO A 1 321 ? 213.074 228.636 164.334 1.00 58.08  ? 321  PRO D N   1 
ATOM   2471 C CA  . PRO A 1 321 ? 213.932 228.635 165.526 1.00 58.08  ? 321  PRO D CA  1 
ATOM   2472 C C   . PRO A 1 321 ? 214.940 229.776 165.503 1.00 58.08  ? 321  PRO D C   1 
ATOM   2473 O O   . PRO A 1 321 ? 215.157 230.447 164.493 1.00 58.08  ? 321  PRO D O   1 
ATOM   2474 C CB  . PRO A 1 321 ? 214.634 227.274 165.461 1.00 58.08  ? 321  PRO D CB  1 
ATOM   2475 C CG  . PRO A 1 321 ? 213.763 226.434 164.586 1.00 58.08  ? 321  PRO D CG  1 
ATOM   2476 C CD  . PRO A 1 321 ? 213.182 227.376 163.580 1.00 58.08  ? 321  PRO D CD  1 
ATOM   2477 N N   . ASN A 1 322 ? 215.565 229.985 166.660 1.00 63.25  ? 322  ASN D N   1 
ATOM   2478 C CA  . ASN A 1 322 ? 216.580 231.016 166.806 1.00 63.25  ? 322  ASN D CA  1 
ATOM   2479 C C   . ASN A 1 322 ? 217.853 230.622 166.060 1.00 63.25  ? 322  ASN D C   1 
ATOM   2480 O O   . ASN A 1 322 ? 217.965 229.539 165.478 1.00 63.25  ? 322  ASN D O   1 
ATOM   2481 C CB  . ASN A 1 322 ? 216.892 231.255 168.282 1.00 63.25  ? 322  ASN D CB  1 
ATOM   2482 C CG  . ASN A 1 322 ? 215.789 231.998 169.004 1.00 63.25  ? 322  ASN D CG  1 
ATOM   2483 O OD1 . ASN A 1 322 ? 215.030 232.752 168.397 1.00 63.25  ? 322  ASN D OD1 1 
ATOM   2484 N ND2 . ASN A 1 322 ? 215.700 231.790 170.312 1.00 63.25  ? 322  ASN D ND2 1 
ATOM   2485 N N   . MET A 1 323 ? 218.829 231.522 166.087 1.00 59.79  ? 323  MET D N   1 
ATOM   2486 C CA  . MET A 1 323 ? 220.150 231.247 165.547 1.00 59.79  ? 323  MET D CA  1 
ATOM   2487 C C   . MET A 1 323 ? 221.009 230.568 166.605 1.00 59.79  ? 323  MET D C   1 
ATOM   2488 O O   . MET A 1 323 ? 220.892 230.849 167.801 1.00 59.79  ? 323  MET D O   1 
ATOM   2489 C CB  . MET A 1 323 ? 220.824 232.537 165.076 1.00 59.79  ? 323  MET D CB  1 
ATOM   2490 C CG  . MET A 1 323 ? 219.992 233.376 164.115 1.00 59.79  ? 323  MET D CG  1 
ATOM   2491 S SD  . MET A 1 323 ? 220.436 233.163 162.379 1.00 59.79  ? 323  MET D SD  1 
ATOM   2492 C CE  . MET A 1 323 ? 219.686 231.582 162.009 1.00 59.79  ? 323  MET D CE  1 
ATOM   2493 N N   . THR A 1 324 ? 221.872 229.664 166.153 1.00 60.53  ? 324  THR D N   1 
ATOM   2494 C CA  . THR A 1 324 ? 222.740 228.942 167.069 1.00 60.53  ? 324  THR D CA  1 
ATOM   2495 C C   . THR A 1 324 ? 223.748 229.888 167.715 1.00 60.53  ? 324  THR D C   1 
ATOM   2496 O O   . THR A 1 324 ? 224.034 230.978 167.211 1.00 60.53  ? 324  THR D O   1 
ATOM   2497 C CB  . THR A 1 324 ? 223.473 227.815 166.341 1.00 60.53  ? 324  THR D CB  1 
ATOM   2498 O OG1 . THR A 1 324 ? 224.248 228.362 165.267 1.00 60.53  ? 324  THR D OG1 1 
ATOM   2499 C CG2 . THR A 1 324 ? 222.480 226.809 165.781 1.00 60.53  ? 324  THR D CG2 1 
ATOM   2500 N N   . GLN A 1 325 ? 224.287 229.456 168.857 1.00 61.08  ? 325  GLN D N   1 
ATOM   2501 C CA  . GLN A 1 325 ? 225.287 230.260 169.551 1.00 61.08  ? 325  GLN D CA  1 
ATOM   2502 C C   . GLN A 1 325 ? 226.571 230.362 168.737 1.00 61.08  ? 325  GLN D C   1 
ATOM   2503 O O   . GLN A 1 325 ? 227.241 231.403 168.749 1.00 61.08  ? 325  GLN D O   1 
ATOM   2504 C CB  . GLN A 1 325 ? 225.569 229.668 170.932 1.00 61.08  ? 325  GLN D CB  1 
ATOM   2505 C CG  . GLN A 1 325 ? 226.548 230.472 171.769 1.00 61.08  ? 325  GLN D CG  1 
ATOM   2506 C CD  . GLN A 1 325 ? 226.818 229.837 173.118 1.00 61.08  ? 325  GLN D CD  1 
ATOM   2507 O OE1 . GLN A 1 325 ? 226.294 228.767 173.429 1.00 61.08  ? 325  GLN D OE1 1 
ATOM   2508 N NE2 . GLN A 1 325 ? 227.639 230.494 173.928 1.00 61.08  ? 325  GLN D NE2 1 
ATOM   2509 N N   . GLY A 1 326 ? 226.929 229.290 168.026 1.00 59.26  ? 326  GLY D N   1 
ATOM   2510 C CA  . GLY A 1 326 ? 228.086 229.345 167.152 1.00 59.26  ? 326  GLY D CA  1 
ATOM   2511 C C   . GLY A 1 326 ? 227.941 230.371 166.048 1.00 59.26  ? 326  GLY D C   1 
ATOM   2512 O O   . GLY A 1 326 ? 228.928 230.982 165.630 1.00 59.26  ? 326  GLY D O   1 
ATOM   2513 N N   . PHE A 1 327 ? 226.713 230.584 165.569 1.00 57.08  ? 327  PHE D N   1 
ATOM   2514 C CA  . PHE A 1 327 ? 226.479 231.606 164.556 1.00 57.08  ? 327  PHE D CA  1 
ATOM   2515 C C   . PHE A 1 327 ? 226.818 232.998 165.073 1.00 57.08  ? 327  PHE D C   1 
ATOM   2516 O O   . PHE A 1 327 ? 227.238 233.863 164.297 1.00 57.08  ? 327  PHE D O   1 
ATOM   2517 C CB  . PHE A 1 327 ? 225.026 231.552 164.084 1.00 57.08  ? 327  PHE D CB  1 
ATOM   2518 C CG  . PHE A 1 327 ? 224.624 232.713 163.221 1.00 57.08  ? 327  PHE D CG  1 
ATOM   2519 C CD1 . PHE A 1 327 ? 223.891 233.764 163.747 1.00 57.08  ? 327  PHE D CD1 1 
ATOM   2520 C CD2 . PHE A 1 327 ? 224.982 232.757 161.886 1.00 57.08  ? 327  PHE D CD2 1 
ATOM   2521 C CE1 . PHE A 1 327 ? 223.522 234.835 162.957 1.00 57.08  ? 327  PHE D CE1 1 
ATOM   2522 C CE2 . PHE A 1 327 ? 224.615 233.824 161.091 1.00 57.08  ? 327  PHE D CE2 1 
ATOM   2523 C CZ  . PHE A 1 327 ? 223.884 234.864 161.627 1.00 57.08  ? 327  PHE D CZ  1 
ATOM   2524 N N   . TRP A 1 328 ? 226.645 233.234 166.372 1.00 57.40  ? 328  TRP D N   1 
ATOM   2525 C CA  . TRP A 1 328 ? 226.937 234.541 166.944 1.00 57.40  ? 328  TRP D CA  1 
ATOM   2526 C C   . TRP A 1 328 ? 228.367 234.664 167.446 1.00 57.40  ? 328  TRP D C   1 
ATOM   2527 O O   . TRP A 1 328 ? 228.907 235.776 167.481 1.00 57.40  ? 328  TRP D O   1 
ATOM   2528 C CB  . TRP A 1 328 ? 225.967 234.847 168.088 1.00 57.40  ? 328  TRP D CB  1 
ATOM   2529 C CG  . TRP A 1 328 ? 224.557 235.043 167.633 1.00 57.40  ? 328  TRP D CG  1 
ATOM   2530 C CD1 . TRP A 1 328 ? 223.522 234.165 167.767 1.00 57.40  ? 328  TRP D CD1 1 
ATOM   2531 C CD2 . TRP A 1 328 ? 224.027 236.188 166.958 1.00 57.40  ? 328  TRP D CD2 1 
ATOM   2532 N NE1 . TRP A 1 328 ? 222.378 234.695 167.223 1.00 57.40  ? 328  TRP D NE1 1 
ATOM   2533 C CE2 . TRP A 1 328 ? 222.662 235.937 166.718 1.00 57.40  ? 328  TRP D CE2 1 
ATOM   2534 C CE3 . TRP A 1 328 ? 224.573 237.404 166.535 1.00 57.40  ? 328  TRP D CE3 1 
ATOM   2535 C CZ2 . TRP A 1 328 ? 221.836 236.855 166.075 1.00 57.40  ? 328  TRP D CZ2 1 
ATOM   2536 C CZ3 . TRP A 1 328 ? 223.751 238.313 165.896 1.00 57.40  ? 328  TRP D CZ3 1 
ATOM   2537 C CH2 . TRP A 1 328 ? 222.398 238.035 165.673 1.00 57.40  ? 328  TRP D CH2 1 
ATOM   2538 N N   . GLU A 1 329 ? 228.997 233.557 167.834 1.00 59.41  ? 329  GLU D N   1 
ATOM   2539 C CA  . GLU A 1 329 ? 230.353 233.596 168.364 1.00 59.41  ? 329  GLU D CA  1 
ATOM   2540 C C   . GLU A 1 329 ? 231.411 233.193 167.345 1.00 59.41  ? 329  GLU D C   1 
ATOM   2541 O O   . GLU A 1 329 ? 232.593 233.130 167.695 1.00 59.41  ? 329  GLU D O   1 
ATOM   2542 C CB  . GLU A 1 329 ? 230.466 232.699 169.602 1.00 59.41  ? 329  GLU D CB  1 
ATOM   2543 C CG  . GLU A 1 329 ? 230.400 231.213 169.306 1.00 59.41  ? 329  GLU D CG  1 
ATOM   2544 C CD  . GLU A 1 329 ? 230.535 230.367 170.556 1.00 59.41  ? 329  GLU D CD  1 
ATOM   2545 O OE1 . GLU A 1 329 ? 230.689 230.945 171.652 1.00 59.41  ? 329  GLU D OE1 1 
ATOM   2546 O OE2 . GLU A 1 329 ? 230.487 229.124 170.443 1.00 59.41  ? 329  GLU D OE2 1 
ATOM   2547 N N   . ASN A 1 330 ? 231.024 232.921 166.098 1.00 57.52  ? 330  ASN D N   1 
ATOM   2548 C CA  . ASN A 1 330 ? 231.979 232.516 165.074 1.00 57.52  ? 330  ASN D CA  1 
ATOM   2549 C C   . ASN A 1 330 ? 231.848 233.263 163.756 1.00 57.52  ? 330  ASN D C   1 
ATOM   2550 O O   . ASN A 1 330 ? 232.815 233.276 162.985 1.00 57.52  ? 330  ASN D O   1 
ATOM   2551 C CB  . ASN A 1 330 ? 231.859 231.009 164.796 1.00 57.52  ? 330  ASN D CB  1 
ATOM   2552 C CG  . ASN A 1 330 ? 232.150 230.165 166.020 1.00 57.52  ? 330  ASN D CG  1 
ATOM   2553 O OD1 . ASN A 1 330 ? 231.312 229.378 166.459 1.00 57.52  ? 330  ASN D OD1 1 
ATOM   2554 N ND2 . ASN A 1 330 ? 233.343 230.325 166.579 1.00 57.52  ? 330  ASN D ND2 1 
ATOM   2555 N N   . SER A 1 331 ? 230.706 233.879 163.464 1.00 57.95  ? 331  SER D N   1 
ATOM   2556 C CA  . SER A 1 331 ? 230.535 234.591 162.207 1.00 57.95  ? 331  SER D CA  1 
ATOM   2557 C C   . SER A 1 331 ? 231.202 235.960 162.267 1.00 57.95  ? 331  SER D C   1 
ATOM   2558 O O   . SER A 1 331 ? 231.368 236.550 163.338 1.00 57.95  ? 331  SER D O   1 
ATOM   2559 C CB  . SER A 1 331 ? 229.052 234.754 161.875 1.00 57.95  ? 331  SER D CB  1 
ATOM   2560 O OG  . SER A 1 331 ? 228.392 233.501 161.854 1.00 57.95  ? 331  SER D OG  1 
ATOM   2561 N N   . MET A 1 332 ? 231.582 236.462 161.097 1.00 63.25  ? 332  MET D N   1 
ATOM   2562 C CA  . MET A 1 332 ? 232.201 237.778 160.957 1.00 63.25  ? 332  MET D CA  1 
ATOM   2563 C C   . MET A 1 332 ? 231.182 238.686 160.272 1.00 63.25  ? 332  MET D C   1 
ATOM   2564 O O   . MET A 1 332 ? 231.128 238.772 159.044 1.00 63.25  ? 332  MET D O   1 
ATOM   2565 C CB  . MET A 1 332 ? 233.507 237.695 160.172 1.00 63.25  ? 332  MET D CB  1 
ATOM   2566 C CG  . MET A 1 332 ? 234.351 238.956 160.248 1.00 63.25  ? 332  MET D CG  1 
ATOM   2567 S SD  . MET A 1 332 ? 235.943 238.794 159.417 1.00 63.25  ? 332  MET D SD  1 
ATOM   2568 C CE  . MET A 1 332 ? 235.419 238.592 157.718 1.00 63.25  ? 332  MET D CE  1 
ATOM   2569 N N   . LEU A 1 333 ? 230.371 239.365 161.080 1.00 60.03  ? 333  LEU D N   1 
ATOM   2570 C CA  . LEU A 1 333 ? 229.305 240.217 160.570 1.00 60.03  ? 333  LEU D CA  1 
ATOM   2571 C C   . LEU A 1 333 ? 229.777 241.621 160.216 1.00 60.03  ? 333  LEU D C   1 
ATOM   2572 O O   . LEU A 1 333 ? 228.969 242.424 159.739 1.00 60.03  ? 333  LEU D O   1 
ATOM   2573 C CB  . LEU A 1 333 ? 228.170 240.301 161.594 1.00 60.03  ? 333  LEU D CB  1 
ATOM   2574 C CG  . LEU A 1 333 ? 227.610 238.964 162.083 1.00 60.03  ? 333  LEU D CG  1 
ATOM   2575 C CD1 . LEU A 1 333 ? 226.505 239.184 163.104 1.00 60.03  ? 333  LEU D CD1 1 
ATOM   2576 C CD2 . LEU A 1 333 ? 227.108 238.133 160.914 1.00 60.03  ? 333  LEU D CD2 1 
ATOM   2577 N N   . THR A 1 334 ? 231.051 241.937 160.433 1.00 63.35  ? 334  THR D N   1 
ATOM   2578 C CA  . THR A 1 334 ? 231.584 243.255 160.130 1.00 63.35  ? 334  THR D CA  1 
ATOM   2579 C C   . THR A 1 334 ? 232.980 243.097 159.545 1.00 63.35  ? 334  THR D C   1 
ATOM   2580 O O   . THR A 1 334 ? 233.629 242.061 159.710 1.00 63.35  ? 334  THR D O   1 
ATOM   2581 C CB  . THR A 1 334 ? 231.623 244.150 161.380 1.00 63.35  ? 334  THR D CB  1 
ATOM   2582 O OG1 . THR A 1 334 ? 230.495 243.857 162.214 1.00 63.35  ? 334  THR D OG1 1 
ATOM   2583 C CG2 . THR A 1 334 ? 231.573 245.621 160.991 1.00 63.35  ? 334  THR D CG2 1 
ATOM   2584 N N   . ASP A 1 335 ? 233.433 244.134 158.851 1.00 70.41  ? 335  ASP D N   1 
ATOM   2585 C CA  . ASP A 1 335 ? 234.765 244.111 158.265 1.00 70.41  ? 335  ASP D CA  1 
ATOM   2586 C C   . ASP A 1 335 ? 235.814 244.051 159.372 1.00 70.41  ? 335  ASP D C   1 
ATOM   2587 O O   . ASP A 1 335 ? 235.748 244.841 160.325 1.00 70.41  ? 335  ASP D O   1 
ATOM   2588 C CB  . ASP A 1 335 ? 234.988 245.343 157.391 1.00 70.41  ? 335  ASP D CB  1 
ATOM   2589 C CG  . ASP A 1 335 ? 236.370 245.374 156.771 1.00 70.41  ? 335  ASP D CG  1 
ATOM   2590 O OD1 . ASP A 1 335 ? 236.638 244.552 155.870 1.00 70.41  ? 335  ASP D OD1 1 
ATOM   2591 O OD2 . ASP A 1 335 ? 237.190 246.221 157.185 1.00 70.41  ? 335  ASP D OD2 1 
ATOM   2592 N N   . PRO A 1 336 ? 236.786 243.139 159.291 1.00 72.06  ? 336  PRO D N   1 
ATOM   2593 C CA  . PRO A 1 336 ? 237.777 243.039 160.373 1.00 72.06  ? 336  PRO D CA  1 
ATOM   2594 C C   . PRO A 1 336 ? 238.715 244.230 160.444 1.00 72.06  ? 336  PRO D C   1 
ATOM   2595 O O   . PRO A 1 336 ? 239.198 244.558 161.535 1.00 72.06  ? 336  PRO D O   1 
ATOM   2596 C CB  . PRO A 1 336 ? 238.529 241.744 160.039 1.00 72.06  ? 336  PRO D CB  1 
ATOM   2597 C CG  . PRO A 1 336 ? 238.383 241.605 158.560 1.00 72.06  ? 336  PRO D CG  1 
ATOM   2598 C CD  . PRO A 1 336 ? 237.021 242.148 158.227 1.00 72.06  ? 336  PRO D CD  1 
ATOM   2599 N N   . GLY A 1 337 ? 238.987 244.885 159.324 1.00 75.48  ? 337  GLY D N   1 
ATOM   2600 C CA  . GLY A 1 337 ? 239.867 246.029 159.292 1.00 75.48  ? 337  GLY D CA  1 
ATOM   2601 C C   . GLY A 1 337 ? 240.766 245.968 158.077 1.00 75.48  ? 337  GLY D C   1 
ATOM   2602 O O   . GLY A 1 337 ? 240.518 245.212 157.140 1.00 75.48  ? 337  GLY D O   1 
ATOM   2603 N N   . ASN A 1 338 ? 241.822 246.780 158.105 1.00 82.04  ? 338  ASN D N   1 
ATOM   2604 C CA  . ASN A 1 338 ? 242.772 246.836 157.003 1.00 82.04  ? 338  ASN D CA  1 
ATOM   2605 C C   . ASN A 1 338 ? 243.905 245.829 157.140 1.00 82.04  ? 338  ASN D C   1 
ATOM   2606 O O   . ASN A 1 338 ? 244.527 245.478 156.131 1.00 82.04  ? 338  ASN D O   1 
ATOM   2607 C CB  . ASN A 1 338 ? 243.361 248.245 156.884 1.00 82.04  ? 338  ASN D CB  1 
ATOM   2608 C CG  . ASN A 1 338 ? 244.087 248.681 158.142 1.00 82.04  ? 338  ASN D CG  1 
ATOM   2609 O OD1 . ASN A 1 338 ? 245.289 248.458 158.288 1.00 82.04  ? 338  ASN D OD1 1 
ATOM   2610 N ND2 . ASN A 1 338 ? 243.358 249.307 159.059 1.00 82.04  ? 338  ASN D ND2 1 
ATOM   2611 N N   . VAL A 1 339 ? 244.186 245.356 158.356 1.00 79.55  ? 339  VAL D N   1 
ATOM   2612 C CA  . VAL A 1 339 ? 245.274 244.402 158.541 1.00 79.55  ? 339  VAL D CA  1 
ATOM   2613 C C   . VAL A 1 339 ? 244.877 243.022 158.030 1.00 79.55  ? 339  VAL D C   1 
ATOM   2614 O O   . VAL A 1 339 ? 245.717 242.281 157.504 1.00 79.55  ? 339  VAL D O   1 
ATOM   2615 C CB  . VAL A 1 339 ? 245.702 244.367 160.021 1.00 79.55  ? 339  VAL D CB  1 
ATOM   2616 C CG1 . VAL A 1 339 ? 244.518 244.032 160.919 1.00 79.55  ? 339  VAL D CG1 1 
ATOM   2617 C CG2 . VAL A 1 339 ? 246.843 243.381 160.233 1.00 79.55  ? 339  VAL D CG2 1 
ATOM   2618 N N   . GLN A 1 340 ? 243.604 242.659 158.153 1.00 74.65  ? 340  GLN D N   1 
ATOM   2619 C CA  . GLN A 1 340 ? 243.101 241.371 157.698 1.00 74.65  ? 340  GLN D CA  1 
ATOM   2620 C C   . GLN A 1 340 ? 242.216 241.580 156.478 1.00 74.65  ? 340  GLN D C   1 
ATOM   2621 O O   . GLN A 1 340 ? 241.269 242.373 156.520 1.00 74.65  ? 340  GLN D O   1 
ATOM   2622 C CB  . GLN A 1 340 ? 242.320 240.665 158.808 1.00 74.65  ? 340  GLN D CB  1 
ATOM   2623 C CG  . GLN A 1 340 ? 241.796 239.293 158.424 1.00 74.65  ? 340  GLN D CG  1 
ATOM   2624 C CD  . GLN A 1 340 ? 241.061 238.614 159.562 1.00 74.65  ? 340  GLN D CD  1 
ATOM   2625 O OE1 . GLN A 1 340 ? 240.925 239.173 160.650 1.00 74.65  ? 340  GLN D OE1 1 
ATOM   2626 N NE2 . GLN A 1 340 ? 240.584 237.399 159.317 1.00 74.65  ? 340  GLN D NE2 1 
ATOM   2627 N N   . LYS A 1 341 ? 242.525 240.871 155.397 1.00 70.55  ? 341  LYS D N   1 
ATOM   2628 C CA  . LYS A 1 341 ? 241.785 240.983 154.149 1.00 70.55  ? 341  LYS D CA  1 
ATOM   2629 C C   . LYS A 1 341 ? 240.779 239.848 154.031 1.00 70.55  ? 341  LYS D C   1 
ATOM   2630 O O   . LYS A 1 341 ? 241.084 238.696 154.354 1.00 70.55  ? 341  LYS D O   1 
ATOM   2631 C CB  . LYS A 1 341 ? 242.734 240.968 152.949 1.00 70.55  ? 341  LYS D CB  1 
ATOM   2632 C CG  . LYS A 1 341 ? 243.732 242.112 152.933 1.00 70.55  ? 341  LYS D CG  1 
ATOM   2633 C CD  . LYS A 1 341 ? 244.608 242.064 151.694 1.00 70.55  ? 341  LYS D CD  1 
ATOM   2634 C CE  . LYS A 1 341 ? 243.776 242.167 150.427 1.00 70.55  ? 341  LYS D CE  1 
ATOM   2635 N NZ  . LYS A 1 341 ? 242.991 243.431 150.380 1.00 70.55  ? 341  LYS D NZ  1 
ATOM   2636 N N   . ALA A 1 342 ? 239.576 240.182 153.570 1.00 66.83  ? 342  ALA D N   1 
ATOM   2637 C CA  . ALA A 1 342 ? 238.521 239.197 153.391 1.00 66.83  ? 342  ALA D CA  1 
ATOM   2638 C C   . ALA A 1 342 ? 237.670 239.596 152.196 1.00 66.83  ? 342  ALA D C   1 
ATOM   2639 O O   . ALA A 1 342 ? 237.640 240.760 151.791 1.00 66.83  ? 342  ALA D O   1 
ATOM   2640 C CB  . ALA A 1 342 ? 237.655 239.062 154.649 1.00 66.83  ? 342  ALA D CB  1 
ATOM   2641 N N   . VAL A 1 343 ? 236.978 238.611 151.633 1.00 65.61  ? 343  VAL D N   1 
ATOM   2642 C CA  . VAL A 1 343 ? 236.096 238.850 150.496 1.00 65.61  ? 343  VAL D CA  1 
ATOM   2643 C C   . VAL A 1 343 ? 234.759 239.365 151.017 1.00 65.61  ? 343  VAL D C   1 
ATOM   2644 O O   . VAL A 1 343 ? 234.072 238.684 151.785 1.00 65.61  ? 343  VAL D O   1 
ATOM   2645 C CB  . VAL A 1 343 ? 235.918 237.578 149.653 1.00 65.61  ? 343  VAL D CB  1 
ATOM   2646 C CG1 . VAL A 1 343 ? 235.751 236.356 150.547 1.00 65.61  ? 343  VAL D CG1 1 
ATOM   2647 C CG2 . VAL A 1 343 ? 234.733 237.726 148.711 1.00 65.61  ? 343  VAL D CG2 1 
ATOM   2648 N N   . CYS A 1 344 ? 234.394 240.579 150.610 1.00 70.43  ? 344  CYS D N   1 
ATOM   2649 C CA  . CYS A 1 344 ? 233.159 241.211 151.074 1.00 70.43  ? 344  CYS D CA  1 
ATOM   2650 C C   . CYS A 1 344 ? 232.001 240.894 150.126 1.00 70.43  ? 344  CYS D C   1 
ATOM   2651 O O   . CYS A 1 344 ? 231.391 241.769 149.513 1.00 70.43  ? 344  CYS D O   1 
ATOM   2652 C CB  . CYS A 1 344 ? 233.359 242.714 151.228 1.00 70.43  ? 344  CYS D CB  1 
ATOM   2653 S SG  . CYS A 1 344 ? 234.336 243.187 152.673 1.00 70.43  ? 344  CYS D SG  1 
ATOM   2654 N N   . HIS A 1 345 ? 231.705 239.602 150.019 1.00 61.86  ? 345  HIS D N   1 
ATOM   2655 C CA  . HIS A 1 345 ? 230.565 239.118 149.252 1.00 61.86  ? 345  HIS D CA  1 
ATOM   2656 C C   . HIS A 1 345 ? 229.632 238.370 150.194 1.00 61.86  ? 345  HIS D C   1 
ATOM   2657 O O   . HIS A 1 345 ? 230.050 237.370 150.803 1.00 61.86  ? 345  HIS D O   1 
ATOM   2658 C CB  . HIS A 1 345 ? 231.014 238.210 148.105 1.00 61.86  ? 345  HIS D CB  1 
ATOM   2659 C CG  . HIS A 1 345 ? 229.907 237.817 147.178 1.00 61.86  ? 345  HIS D CG  1 
ATOM   2660 N ND1 . HIS A 1 345 ? 229.259 236.604 147.264 1.00 61.86  ? 345  HIS D ND1 1 
ATOM   2661 C CD2 . HIS A 1 345 ? 229.332 238.478 146.146 1.00 61.86  ? 345  HIS D CD2 1 
ATOM   2662 C CE1 . HIS A 1 345 ? 228.333 236.534 146.324 1.00 61.86  ? 345  HIS D CE1 1 
ATOM   2663 N NE2 . HIS A 1 345 ? 228.357 237.659 145.632 1.00 61.86  ? 345  HIS D NE2 1 
ATOM   2664 N N   . PRO A 1 346 ? 228.382 238.809 150.359 1.00 56.57  ? 346  PRO D N   1 
ATOM   2665 C CA  . PRO A 1 346 ? 227.482 238.143 151.312 1.00 56.57  ? 346  PRO D CA  1 
ATOM   2666 C C   . PRO A 1 346 ? 227.184 236.702 150.934 1.00 56.57  ? 346  PRO D C   1 
ATOM   2667 O O   . PRO A 1 346 ? 226.551 236.437 149.906 1.00 56.57  ? 346  PRO D O   1 
ATOM   2668 C CB  . PRO A 1 346 ? 226.214 239.007 151.260 1.00 56.57  ? 346  PRO D CB  1 
ATOM   2669 C CG  . PRO A 1 346 ? 226.670 240.328 150.725 1.00 56.57  ? 346  PRO D CG  1 
ATOM   2670 C CD  . PRO A 1 346 ? 227.770 240.008 149.764 1.00 56.57  ? 346  PRO D CD  1 
ATOM   2671 N N   . THR A 1 347 ? 227.638 235.762 151.761 1.00 53.83  ? 347  THR D N   1 
ATOM   2672 C CA  . THR A 1 347 ? 227.428 234.343 151.519 1.00 53.83  ? 347  THR D CA  1 
ATOM   2673 C C   . THR A 1 347 ? 226.990 233.667 152.809 1.00 53.83  ? 347  THR D C   1 
ATOM   2674 O O   . THR A 1 347 ? 227.418 234.043 153.903 1.00 53.83  ? 347  THR D O   1 
ATOM   2675 C CB  . THR A 1 347 ? 228.694 233.656 150.984 1.00 53.83  ? 347  THR D CB  1 
ATOM   2676 O OG1 . THR A 1 347 ? 229.797 233.932 151.857 1.00 53.83  ? 347  THR D OG1 1 
ATOM   2677 C CG2 . THR A 1 347 ? 229.024 234.145 149.582 1.00 53.83  ? 347  THR D CG2 1 
ATOM   2678 N N   . ALA A 1 348 ? 226.128 232.664 152.668 1.00 53.43  ? 348  ALA D N   1 
ATOM   2679 C CA  . ALA A 1 348 ? 225.671 231.851 153.787 1.00 53.43  ? 348  ALA D CA  1 
ATOM   2680 C C   . ALA A 1 348 ? 226.467 230.553 153.802 1.00 53.43  ? 348  ALA D C   1 
ATOM   2681 O O   . ALA A 1 348 ? 226.476 229.815 152.811 1.00 53.43  ? 348  ALA D O   1 
ATOM   2682 C CB  . ALA A 1 348 ? 224.174 231.568 153.683 1.00 53.43  ? 348  ALA D CB  1 
ATOM   2683 N N   . TRP A 1 349 ? 227.129 230.277 154.921 1.00 54.10  ? 349  TRP D N   1 
ATOM   2684 C CA  . TRP A 1 349 ? 228.022 229.133 155.041 1.00 54.10  ? 349  TRP D CA  1 
ATOM   2685 C C   . TRP A 1 349 ? 227.351 228.017 155.829 1.00 54.10  ? 349  TRP D C   1 
ATOM   2686 O O   . TRP A 1 349 ? 226.887 228.233 156.954 1.00 54.10  ? 349  TRP D O   1 
ATOM   2687 C CB  . TRP A 1 349 ? 229.333 229.538 155.714 1.00 54.10  ? 349  TRP D CB  1 
ATOM   2688 C CG  . TRP A 1 349 ? 230.215 230.363 154.835 1.00 54.10  ? 349  TRP D CG  1 
ATOM   2689 C CD1 . TRP A 1 349 ? 230.168 231.715 154.664 1.00 54.10  ? 349  TRP D CD1 1 
ATOM   2690 C CD2 . TRP A 1 349 ? 231.277 229.889 154.000 1.00 54.10  ? 349  TRP D CD2 1 
ATOM   2691 N NE1 . TRP A 1 349 ? 231.136 232.113 153.775 1.00 54.10  ? 349  TRP D NE1 1 
ATOM   2692 C CE2 . TRP A 1 349 ? 231.830 231.010 153.353 1.00 54.10  ? 349  TRP D CE2 1 
ATOM   2693 C CE3 . TRP A 1 349 ? 231.814 228.625 153.738 1.00 54.10  ? 349  TRP D CE3 1 
ATOM   2694 C CZ2 . TRP A 1 349 ? 232.894 230.906 152.461 1.00 54.10  ? 349  TRP D CZ2 1 
ATOM   2695 C CZ3 . TRP A 1 349 ? 232.869 228.525 152.852 1.00 54.10  ? 349  TRP D CZ3 1 
ATOM   2696 C CH2 . TRP A 1 349 ? 233.398 229.658 152.224 1.00 54.10  ? 349  TRP D CH2 1 
ATOM   2697 N N   . ASP A 1 350 ? 227.304 226.829 155.234 1.00 54.25  ? 350  ASP D N   1 
ATOM   2698 C CA  . ASP A 1 350 ? 226.804 225.622 155.885 1.00 54.25  ? 350  ASP D CA  1 
ATOM   2699 C C   . ASP A 1 350 ? 227.994 224.683 156.058 1.00 54.25  ? 350  ASP D C   1 
ATOM   2700 O O   . ASP A 1 350 ? 228.382 223.980 155.121 1.00 54.25  ? 350  ASP D O   1 
ATOM   2701 C CB  . ASP A 1 350 ? 225.689 224.977 155.067 1.00 54.25  ? 350  ASP D CB  1 
ATOM   2702 C CG  . ASP A 1 350 ? 225.059 223.789 155.771 1.00 54.25  ? 350  ASP D CG  1 
ATOM   2703 O OD1 . ASP A 1 350 ? 225.371 223.559 156.958 1.00 54.25  ? 350  ASP D OD1 1 
ATOM   2704 O OD2 . ASP A 1 350 ? 224.250 223.083 155.134 1.00 54.25  ? 350  ASP D OD2 1 
ATOM   2705 N N   . LEU A 1 351 ? 228.574 224.681 157.260 1.00 54.90  ? 351  LEU D N   1 
ATOM   2706 C CA  . LEU A 1 351 ? 229.754 223.860 157.508 1.00 54.90  ? 351  LEU D CA  1 
ATOM   2707 C C   . LEU A 1 351 ? 229.410 222.375 157.489 1.00 54.90  ? 351  LEU D C   1 
ATOM   2708 O O   . LEU A 1 351 ? 230.215 221.552 157.040 1.00 54.90  ? 351  LEU D O   1 
ATOM   2709 C CB  . LEU A 1 351 ? 230.399 224.250 158.839 1.00 54.90  ? 351  LEU D CB  1 
ATOM   2710 C CG  . LEU A 1 351 ? 231.107 225.608 158.940 1.00 54.90  ? 351  LEU D CG  1 
ATOM   2711 C CD1 . LEU A 1 351 ? 231.999 225.849 157.734 1.00 54.90  ? 351  LEU D CD1 1 
ATOM   2712 C CD2 . LEU A 1 351 ? 230.129 226.763 159.128 1.00 54.90  ? 351  LEU D CD2 1 
ATOM   2713 N N   . GLY A 1 352 ? 228.222 222.015 157.968 1.00 55.17  ? 352  GLY D N   1 
ATOM   2714 C CA  . GLY A 1 352 ? 227.758 220.645 157.882 1.00 55.17  ? 352  GLY D CA  1 
ATOM   2715 C C   . GLY A 1 352 ? 227.521 219.970 159.217 1.00 55.17  ? 352  GLY D C   1 
ATOM   2716 O O   . GLY A 1 352 ? 226.522 219.265 159.390 1.00 55.17  ? 352  GLY D O   1 
ATOM   2717 N N   . LYS A 1 353 ? 228.424 220.174 160.170 1.00 53.53  ? 353  LYS D N   1 
ATOM   2718 C CA  . LYS A 1 353 ? 228.309 219.555 161.490 1.00 53.53  ? 353  LYS D CA  1 
ATOM   2719 C C   . LYS A 1 353 ? 227.645 220.514 162.478 1.00 53.53  ? 353  LYS D C   1 
ATOM   2720 O O   . LYS A 1 353 ? 228.201 220.879 163.513 1.00 53.53  ? 353  LYS D O   1 
ATOM   2721 C CB  . LYS A 1 353 ? 229.680 219.104 161.985 1.00 53.53  ? 353  LYS D CB  1 
ATOM   2722 C CG  . LYS A 1 353 ? 230.339 218.057 161.100 1.00 53.53  ? 353  LYS D CG  1 
ATOM   2723 C CD  . LYS A 1 353 ? 231.627 217.535 161.716 1.00 53.53  ? 353  LYS D CD  1 
ATOM   2724 C CE  . LYS A 1 353 ? 231.358 216.793 163.013 1.00 53.53  ? 353  LYS D CE  1 
ATOM   2725 N NZ  . LYS A 1 353 ? 230.474 215.614 162.803 1.00 53.53  ? 353  LYS D NZ  1 
ATOM   2726 N N   . GLY A 1 354 ? 226.424 220.920 162.135 1.00 53.45  ? 354  GLY D N   1 
ATOM   2727 C CA  . GLY A 1 354 ? 225.660 221.816 162.979 1.00 53.45  ? 354  GLY D CA  1 
ATOM   2728 C C   . GLY A 1 354 ? 226.212 223.216 163.103 1.00 53.45  ? 354  GLY D C   1 
ATOM   2729 O O   . GLY A 1 354 ? 225.790 223.954 163.999 1.00 53.45  ? 354  GLY D O   1 
ATOM   2730 N N   . ASP A 1 355 ? 227.138 223.610 162.235 1.00 54.13  ? 355  ASP D N   1 
ATOM   2731 C CA  . ASP A 1 355 ? 227.747 224.932 162.272 1.00 54.13  ? 355  ASP D CA  1 
ATOM   2732 C C   . ASP A 1 355 ? 227.245 225.748 161.090 1.00 54.13  ? 355  ASP D C   1 
ATOM   2733 O O   . ASP A 1 355 ? 227.357 225.315 159.939 1.00 54.13  ? 355  ASP D O   1 
ATOM   2734 C CB  . ASP A 1 355 ? 229.274 224.829 162.243 1.00 54.13  ? 355  ASP D CB  1 
ATOM   2735 C CG  . ASP A 1 355 ? 229.955 226.142 162.575 1.00 54.13  ? 355  ASP D CG  1 
ATOM   2736 O OD1 . ASP A 1 355 ? 229.251 227.104 162.949 1.00 54.13  ? 355  ASP D OD1 1 
ATOM   2737 O OD2 . ASP A 1 355 ? 231.196 226.213 162.462 1.00 54.13  ? 355  ASP D OD2 1 
ATOM   2738 N N   . PHE A 1 356 ? 226.689 226.922 161.379 1.00 52.77  ? 356  PHE D N   1 
ATOM   2739 C CA  . PHE A 1 356 ? 226.147 227.811 160.360 1.00 52.77  ? 356  PHE D CA  1 
ATOM   2740 C C   . PHE A 1 356 ? 226.684 229.213 160.595 1.00 52.77  ? 356  PHE D C   1 
ATOM   2741 O O   . PHE A 1 356 ? 226.567 229.748 161.703 1.00 52.77  ? 356  PHE D O   1 
ATOM   2742 C CB  . PHE A 1 356 ? 224.615 227.817 160.386 1.00 52.77  ? 356  PHE D CB  1 
ATOM   2743 C CG  . PHE A 1 356 ? 224.002 226.448 160.301 1.00 52.77  ? 356  PHE D CG  1 
ATOM   2744 C CD1 . PHE A 1 356 ? 223.730 225.871 159.072 1.00 52.77  ? 356  PHE D CD1 1 
ATOM   2745 C CD2 . PHE A 1 356 ? 223.697 225.738 161.450 1.00 52.77  ? 356  PHE D CD2 1 
ATOM   2746 C CE1 . PHE A 1 356 ? 223.167 224.612 158.992 1.00 52.77  ? 356  PHE D CE1 1 
ATOM   2747 C CE2 . PHE A 1 356 ? 223.134 224.479 161.376 1.00 52.77  ? 356  PHE D CE2 1 
ATOM   2748 C CZ  . PHE A 1 356 ? 222.868 223.916 160.145 1.00 52.77  ? 356  PHE D CZ  1 
ATOM   2749 N N   . ARG A 1 357 ? 227.271 229.806 159.557 1.00 56.08  ? 357  ARG D N   1 
ATOM   2750 C CA  . ARG A 1 357 ? 227.868 231.128 159.662 1.00 56.08  ? 357  ARG D CA  1 
ATOM   2751 C C   . ARG A 1 357 ? 227.490 231.960 158.446 1.00 56.08  ? 357  ARG D C   1 
ATOM   2752 O O   . ARG A 1 357 ? 227.045 231.438 157.421 1.00 56.08  ? 357  ARG D O   1 
ATOM   2753 C CB  . ARG A 1 357 ? 229.396 231.052 159.795 1.00 56.08  ? 357  ARG D CB  1 
ATOM   2754 C CG  . ARG A 1 357 ? 229.878 230.461 161.109 1.00 56.08  ? 357  ARG D CG  1 
ATOM   2755 C CD  . ARG A 1 357 ? 231.373 230.662 161.285 1.00 56.08  ? 357  ARG D CD  1 
ATOM   2756 N NE  . ARG A 1 357 ? 232.162 229.785 160.427 1.00 56.08  ? 357  ARG D NE  1 
ATOM   2757 C CZ  . ARG A 1 357 ? 232.720 228.649 160.833 1.00 56.08  ? 357  ARG D CZ  1 
ATOM   2758 N NH1 . ARG A 1 357 ? 233.423 227.912 159.985 1.00 56.08  ? 357  ARG D NH1 1 
ATOM   2759 N NH2 . ARG A 1 357 ? 232.578 228.252 162.090 1.00 56.08  ? 357  ARG D NH2 1 
ATOM   2760 N N   . ILE A 1 358 ? 227.676 233.272 158.577 1.00 56.52  ? 358  ILE D N   1 
ATOM   2761 C CA  . ILE A 1 358 ? 227.408 234.228 157.509 1.00 56.52  ? 358  ILE D CA  1 
ATOM   2762 C C   . ILE A 1 358 ? 228.636 235.108 157.333 1.00 56.52  ? 358  ILE D C   1 
ATOM   2763 O O   . ILE A 1 358 ? 229.121 235.706 158.300 1.00 56.52  ? 358  ILE D O   1 
ATOM   2764 C CB  . ILE A 1 358 ? 226.164 235.089 157.804 1.00 56.52  ? 358  ILE D CB  1 
ATOM   2765 C CG1 . ILE A 1 358 ? 224.890 234.264 157.629 1.00 56.52  ? 358  ILE D CG1 1 
ATOM   2766 C CG2 . ILE A 1 358 ? 226.134 236.316 156.906 1.00 56.52  ? 358  ILE D CG2 1 
ATOM   2767 C CD1 . ILE A 1 358 ? 223.619 235.047 157.870 1.00 56.52  ? 358  ILE D CD1 1 
ATOM   2768 N N   . LEU A 1 359 ? 229.137 235.185 156.103 1.00 58.31  ? 359  LEU D N   1 
ATOM   2769 C CA  . LEU A 1 359 ? 230.274 236.031 155.761 1.00 58.31  ? 359  LEU D CA  1 
ATOM   2770 C C   . LEU A 1 359 ? 229.751 237.250 155.010 1.00 58.31  ? 359  LEU D C   1 
ATOM   2771 O O   . LEU A 1 359 ? 229.352 237.145 153.846 1.00 58.31  ? 359  LEU D O   1 
ATOM   2772 C CB  . LEU A 1 359 ? 231.292 235.262 154.923 1.00 58.31  ? 359  LEU D CB  1 
ATOM   2773 C CG  . LEU A 1 359 ? 232.470 236.067 154.372 1.00 58.31  ? 359  LEU D CG  1 
ATOM   2774 C CD1 . LEU A 1 359 ? 233.269 236.681 155.505 1.00 58.31  ? 359  LEU D CD1 1 
ATOM   2775 C CD2 . LEU A 1 359 ? 233.356 235.192 153.499 1.00 58.31  ? 359  LEU D CD2 1 
ATOM   2776 N N   . MET A 1 360 ? 229.751 238.403 155.676 1.00 58.93  ? 360  MET D N   1 
ATOM   2777 C CA  . MET A 1 360 ? 229.225 239.621 155.073 1.00 58.93  ? 360  MET D CA  1 
ATOM   2778 C C   . MET A 1 360 ? 229.838 240.828 155.765 1.00 58.93  ? 360  MET D C   1 
ATOM   2779 O O   . MET A 1 360 ? 229.818 240.915 156.996 1.00 58.93  ? 360  MET D O   1 
ATOM   2780 C CB  . MET A 1 360 ? 227.697 239.667 155.175 1.00 58.93  ? 360  MET D CB  1 
ATOM   2781 C CG  . MET A 1 360 ? 227.074 240.927 154.602 1.00 58.93  ? 360  MET D CG  1 
ATOM   2782 S SD  . MET A 1 360 ? 225.282 240.962 154.788 1.00 58.93  ? 360  MET D SD  1 
ATOM   2783 C CE  . MET A 1 360 ? 224.905 242.571 154.099 1.00 58.93  ? 360  MET D CE  1 
ATOM   2784 N N   . CYS A 1 361 ? 230.380 241.753 154.971 1.00 64.57  ? 361  CYS D N   1 
ATOM   2785 C CA  . CYS A 1 361 ? 230.902 243.019 155.484 1.00 64.57  ? 361  CYS D CA  1 
ATOM   2786 C C   . CYS A 1 361 ? 229.731 243.991 155.594 1.00 64.57  ? 361  CYS D C   1 
ATOM   2787 O O   . CYS A 1 361 ? 229.556 244.910 154.790 1.00 64.57  ? 361  CYS D O   1 
ATOM   2788 C CB  . CYS A 1 361 ? 232.004 243.555 154.580 1.00 64.57  ? 361  CYS D CB  1 
ATOM   2789 S SG  . CYS A 1 361 ? 233.325 242.371 154.234 1.00 64.57  ? 361  CYS D SG  1 
ATOM   2790 N N   . THR A 1 362 ? 228.912 243.773 156.620 1.00 62.15  ? 362  THR D N   1 
ATOM   2791 C CA  . THR A 1 362 ? 227.655 244.499 156.757 1.00 62.15  ? 362  THR D CA  1 
ATOM   2792 C C   . THR A 1 362 ? 227.913 245.955 157.122 1.00 62.15  ? 362  THR D C   1 
ATOM   2793 O O   . THR A 1 362 ? 228.555 246.248 158.136 1.00 62.15  ? 362  THR D O   1 
ATOM   2794 C CB  . THR A 1 362 ? 226.774 243.836 157.813 1.00 62.15  ? 362  THR D CB  1 
ATOM   2795 O OG1 . THR A 1 362 ? 226.493 242.486 157.426 1.00 62.15  ? 362  THR D OG1 1 
ATOM   2796 C CG2 . THR A 1 362 ? 225.466 244.597 157.967 1.00 62.15  ? 362  THR D CG2 1 
ATOM   2797 N N   . LYS A 1 363 ? 227.411 246.864 156.294 1.00 61.63  ? 363  LYS D N   1 
ATOM   2798 C CA  . LYS A 1 363 ? 227.397 248.286 156.594 1.00 61.63  ? 363  LYS D CA  1 
ATOM   2799 C C   . LYS A 1 363 ? 225.986 248.712 156.981 1.00 61.63  ? 363  LYS D C   1 
ATOM   2800 O O   . LYS A 1 363 ? 225.009 247.991 156.764 1.00 61.63  ? 363  LYS D O   1 
ATOM   2801 C CB  . LYS A 1 363 ? 227.898 249.097 155.395 1.00 61.63  ? 363  LYS D CB  1 
ATOM   2802 C CG  . LYS A 1 363 ? 229.323 248.774 154.980 1.00 61.63  ? 363  LYS D CG  1 
ATOM   2803 C CD  . LYS A 1 363 ? 229.751 249.601 153.780 1.00 61.63  ? 363  LYS D CD  1 
ATOM   2804 C CE  . LYS A 1 363 ? 228.864 249.327 152.577 1.00 61.63  ? 363  LYS D CE  1 
ATOM   2805 N NZ  . LYS A 1 363 ? 228.911 247.896 152.169 1.00 61.63  ? 363  LYS D NZ  1 
ATOM   2806 N N   . VAL A 1 364 ? 225.883 249.902 157.566 1.00 60.07  ? 364  VAL D N   1 
ATOM   2807 C CA  . VAL A 1 364 ? 224.588 250.400 158.016 1.00 60.07  ? 364  VAL D CA  1 
ATOM   2808 C C   . VAL A 1 364 ? 223.838 250.975 156.818 1.00 60.07  ? 364  VAL D C   1 
ATOM   2809 O O   . VAL A 1 364 ? 224.006 252.145 156.454 1.00 60.07  ? 364  VAL D O   1 
ATOM   2810 C CB  . VAL A 1 364 ? 224.750 251.421 159.162 1.00 60.07  ? 364  VAL D CB  1 
ATOM   2811 C CG1 . VAL A 1 364 ? 225.829 252.457 158.840 1.00 60.07  ? 364  VAL D CG1 1 
ATOM   2812 C CG2 . VAL A 1 364 ? 223.418 252.079 159.499 1.00 60.07  ? 364  VAL D CG2 1 
ATOM   2813 N N   . THR A 1 365 ? 223.025 250.138 156.179 1.00 59.01  ? 365  THR D N   1 
ATOM   2814 C CA  . THR A 1 365 ? 222.273 250.528 154.995 1.00 59.01  ? 365  THR D CA  1 
ATOM   2815 C C   . THR A 1 365 ? 221.053 249.624 154.885 1.00 59.01  ? 365  THR D C   1 
ATOM   2816 O O   . THR A 1 365 ? 221.079 248.473 155.330 1.00 59.01  ? 365  THR D O   1 
ATOM   2817 C CB  . THR A 1 365 ? 223.128 250.434 153.721 1.00 59.01  ? 365  THR D CB  1 
ATOM   2818 O OG1 . THR A 1 365 ? 224.401 251.053 153.944 1.00 59.01  ? 365  THR D OG1 1 
ATOM   2819 C CG2 . THR A 1 365 ? 222.444 251.134 152.554 1.00 59.01  ? 365  THR D CG2 1 
ATOM   2820 N N   . MET A 1 366 ? 219.982 250.161 154.295 1.00 59.70  ? 366  MET D N   1 
ATOM   2821 C CA  . MET A 1 366 ? 218.777 249.365 154.081 1.00 59.70  ? 366  MET D CA  1 
ATOM   2822 C C   . MET A 1 366 ? 219.051 248.188 153.152 1.00 59.70  ? 366  MET D C   1 
ATOM   2823 O O   . MET A 1 366 ? 218.521 247.088 153.355 1.00 59.70  ? 366  MET D O   1 
ATOM   2824 C CB  . MET A 1 366 ? 217.664 250.249 153.518 1.00 59.70  ? 366  MET D CB  1 
ATOM   2825 C CG  . MET A 1 366 ? 216.357 249.522 153.258 1.00 59.70  ? 366  MET D CG  1 
ATOM   2826 S SD  . MET A 1 366 ? 215.106 250.591 152.523 1.00 59.70  ? 366  MET D SD  1 
ATOM   2827 C CE  . MET A 1 366 ? 213.745 249.442 152.339 1.00 59.70  ? 366  MET D CE  1 
ATOM   2828 N N   . ASP A 1 367 ? 219.877 248.402 152.124 1.00 60.06  ? 367  ASP D N   1 
ATOM   2829 C CA  . ASP A 1 367 ? 220.239 247.310 151.227 1.00 60.06  ? 367  ASP D CA  1 
ATOM   2830 C C   . ASP A 1 367 ? 220.943 246.192 151.984 1.00 60.06  ? 367  ASP D C   1 
ATOM   2831 O O   . ASP A 1 367 ? 220.660 245.008 151.764 1.00 60.06  ? 367  ASP D O   1 
ATOM   2832 C CB  . ASP A 1 367 ? 221.121 247.832 150.094 1.00 60.06  ? 367  ASP D CB  1 
ATOM   2833 C CG  . ASP A 1 367 ? 220.430 248.891 149.259 1.00 60.06  ? 367  ASP D CG  1 
ATOM   2834 O OD1 . ASP A 1 367 ? 219.191 248.825 149.120 1.00 60.06  ? 367  ASP D OD1 1 
ATOM   2835 O OD2 . ASP A 1 367 ? 221.125 249.790 148.742 1.00 60.06  ? 367  ASP D OD2 1 
ATOM   2836 N N   . ASP A 1 368 ? 221.856 246.549 152.891 1.00 59.74  ? 368  ASP D N   1 
ATOM   2837 C CA  . ASP A 1 368 ? 222.497 245.536 153.722 1.00 59.74  ? 368  ASP D CA  1 
ATOM   2838 C C   . ASP A 1 368 ? 221.504 244.881 154.671 1.00 59.74  ? 368  ASP D C   1 
ATOM   2839 O O   . ASP A 1 368 ? 221.665 243.707 155.013 1.00 59.74  ? 368  ASP D O   1 
ATOM   2840 C CB  . ASP A 1 368 ? 223.658 246.150 154.503 1.00 59.74  ? 368  ASP D CB  1 
ATOM   2841 C CG  . ASP A 1 368 ? 224.816 246.546 153.609 1.00 59.74  ? 368  ASP D CG  1 
ATOM   2842 O OD1 . ASP A 1 368 ? 224.691 247.555 152.884 1.00 59.74  ? 368  ASP D OD1 1 
ATOM   2843 O OD2 . ASP A 1 368 ? 225.850 245.847 153.629 1.00 59.74  ? 368  ASP D OD2 1 
ATOM   2844 N N   . PHE A 1 369 ? 220.466 245.608 155.087 1.00 57.30  ? 369  PHE D N   1 
ATOM   2845 C CA  . PHE A 1 369 ? 219.417 245.014 155.913 1.00 57.30  ? 369  PHE D CA  1 
ATOM   2846 C C   . PHE A 1 369 ? 218.683 243.913 155.152 1.00 57.30  ? 369  PHE D C   1 
ATOM   2847 O O   . PHE A 1 369 ? 218.510 242.794 155.657 1.00 57.30  ? 369  PHE D O   1 
ATOM   2848 C CB  . PHE A 1 369 ? 218.452 246.112 156.367 1.00 57.30  ? 369  PHE D CB  1 
ATOM   2849 C CG  . PHE A 1 369 ? 217.445 245.666 157.387 1.00 57.30  ? 369  PHE D CG  1 
ATOM   2850 C CD1 . PHE A 1 369 ? 217.790 245.570 158.724 1.00 57.30  ? 369  PHE D CD1 1 
ATOM   2851 C CD2 . PHE A 1 369 ? 216.144 245.374 157.013 1.00 57.30  ? 369  PHE D CD2 1 
ATOM   2852 C CE1 . PHE A 1 369 ? 216.863 245.172 159.666 1.00 57.30  ? 369  PHE D CE1 1 
ATOM   2853 C CE2 . PHE A 1 369 ? 215.212 244.977 157.951 1.00 57.30  ? 369  PHE D CE2 1 
ATOM   2854 C CZ  . PHE A 1 369 ? 215.572 244.876 159.280 1.00 57.30  ? 369  PHE D CZ  1 
ATOM   2855 N N   . LEU A 1 370 ? 218.257 244.212 153.921 1.00 56.15  ? 370  LEU D N   1 
ATOM   2856 C CA  . LEU A 1 370 ? 217.584 243.200 153.112 1.00 56.15  ? 370  LEU D CA  1 
ATOM   2857 C C   . LEU A 1 370 ? 218.521 242.045 152.774 1.00 56.15  ? 370  LEU D C   1 
ATOM   2858 O O   . LEU A 1 370 ? 218.099 240.883 152.736 1.00 56.15  ? 370  LEU D O   1 
ATOM   2859 C CB  . LEU A 1 370 ? 217.020 243.825 151.835 1.00 56.15  ? 370  LEU D CB  1 
ATOM   2860 C CG  . LEU A 1 370 ? 215.676 244.555 151.937 1.00 56.15  ? 370  LEU D CG  1 
ATOM   2861 C CD1 . LEU A 1 370 ? 214.841 244.009 153.089 1.00 56.15  ? 370  LEU D CD1 1 
ATOM   2862 C CD2 . LEU A 1 370 ? 215.855 246.057 152.063 1.00 56.15  ? 370  LEU D CD2 1 
ATOM   2863 N N   . THR A 1 371 ? 219.801 242.342 152.533 1.00 56.45  ? 371  THR D N   1 
ATOM   2864 C CA  . THR A 1 371 ? 220.757 241.281 152.235 1.00 56.45  ? 371  THR D CA  1 
ATOM   2865 C C   . THR A 1 371 ? 220.979 240.382 153.446 1.00 56.45  ? 371  THR D C   1 
ATOM   2866 O O   . THR A 1 371 ? 221.125 239.162 153.304 1.00 56.45  ? 371  THR D O   1 
ATOM   2867 C CB  . THR A 1 371 ? 222.080 241.884 151.762 1.00 56.45  ? 371  THR D CB  1 
ATOM   2868 O OG1 . THR A 1 371 ? 221.831 242.799 150.688 1.00 56.45  ? 371  THR D OG1 1 
ATOM   2869 C CG2 . THR A 1 371 ? 223.018 240.793 151.275 1.00 56.45  ? 371  THR D CG2 1 
ATOM   2870 N N   . ALA A 1 372 ? 221.001 240.965 154.647 1.00 55.72  ? 372  ALA D N   1 
ATOM   2871 C CA  . ALA A 1 372 ? 221.119 240.166 155.859 1.00 55.72  ? 372  ALA D CA  1 
ATOM   2872 C C   . ALA A 1 372 ? 219.890 239.291 156.056 1.00 55.72  ? 372  ALA D C   1 
ATOM   2873 O O   . ALA A 1 372 ? 220.008 238.137 156.481 1.00 55.72  ? 372  ALA D O   1 
ATOM   2874 C CB  . ALA A 1 372 ? 221.335 241.074 157.069 1.00 55.72  ? 372  ALA D CB  1 
ATOM   2875 N N   . HIS A 1 373 ? 218.703 239.822 155.753 1.00 55.17  ? 373  HIS D N   1 
ATOM   2876 C CA  . HIS A 1 373 ? 217.502 238.991 155.808 1.00 55.17  ? 373  HIS D CA  1 
ATOM   2877 C C   . HIS A 1 373 ? 217.585 237.834 154.815 1.00 55.17  ? 373  HIS D C   1 
ATOM   2878 O O   . HIS A 1 373 ? 217.208 236.701 155.136 1.00 55.17  ? 373  HIS D O   1 
ATOM   2879 C CB  . HIS A 1 373 ? 216.258 239.838 155.548 1.00 55.17  ? 373  HIS D CB  1 
ATOM   2880 C CG  . HIS A 1 373 ? 215.634 240.387 156.793 1.00 55.17  ? 373  HIS D CG  1 
ATOM   2881 N ND1 . HIS A 1 373 ? 216.224 241.377 157.548 1.00 55.17  ? 373  HIS D ND1 1 
ATOM   2882 C CD2 . HIS A 1 373 ? 214.475 240.076 157.420 1.00 55.17  ? 373  HIS D CD2 1 
ATOM   2883 C CE1 . HIS A 1 373 ? 215.453 241.655 158.584 1.00 55.17  ? 373  HIS D CE1 1 
ATOM   2884 N NE2 . HIS A 1 373 ? 214.385 240.881 158.529 1.00 55.17  ? 373  HIS D NE2 1 
ATOM   2885 N N   . HIS A 1 374 ? 218.089 238.102 153.609 1.00 53.80  ? 374  HIS D N   1 
ATOM   2886 C CA  . HIS A 1 374 ? 218.252 237.052 152.604 1.00 53.80  ? 374  HIS D CA  1 
ATOM   2887 C C   . HIS A 1 374 ? 219.214 235.968 153.086 1.00 53.80  ? 374  HIS D C   1 
ATOM   2888 O O   . HIS A 1 374 ? 218.932 234.765 152.974 1.00 53.80  ? 374  HIS D O   1 
ATOM   2889 C CB  . HIS A 1 374 ? 218.744 237.681 151.298 1.00 53.80  ? 374  HIS D CB  1 
ATOM   2890 C CG  . HIS A 1 374 ? 219.024 236.695 150.207 1.00 53.80  ? 374  HIS D CG  1 
ATOM   2891 N ND1 . HIS A 1 374 ? 218.057 236.266 149.325 1.00 53.80  ? 374  HIS D ND1 1 
ATOM   2892 C CD2 . HIS A 1 374 ? 220.169 236.070 149.844 1.00 53.80  ? 374  HIS D CD2 1 
ATOM   2893 C CE1 . HIS A 1 374 ? 218.590 235.411 148.471 1.00 53.80  ? 374  HIS D CE1 1 
ATOM   2894 N NE2 . HIS A 1 374 ? 219.871 235.276 148.763 1.00 53.80  ? 374  HIS D NE2 1 
ATOM   2895 N N   . GLU A 1 375 ? 220.360 236.379 153.633 1.00 54.96  ? 375  GLU D N   1 
ATOM   2896 C CA  . GLU A 1 375 ? 221.349 235.410 154.096 1.00 54.96  ? 375  GLU D CA  1 
ATOM   2897 C C   . GLU A 1 375 ? 220.835 234.621 155.294 1.00 54.96  ? 375  GLU D C   1 
ATOM   2898 O O   . GLU A 1 375 ? 221.105 233.419 155.416 1.00 54.96  ? 375  GLU D O   1 
ATOM   2899 C CB  . GLU A 1 375 ? 222.659 236.119 154.437 1.00 54.96  ? 375  GLU D CB  1 
ATOM   2900 C CG  . GLU A 1 375 ? 223.306 236.825 153.256 1.00 54.96  ? 375  GLU D CG  1 
ATOM   2901 C CD  . GLU A 1 375 ? 223.672 235.875 152.132 1.00 54.96  ? 375  GLU D CD  1 
ATOM   2902 O OE1 . GLU A 1 375 ? 223.994 234.703 152.418 1.00 54.96  ? 375  GLU D OE1 1 
ATOM   2903 O OE2 . GLU A 1 375 ? 223.636 236.301 150.958 1.00 54.96  ? 375  GLU D OE2 1 
ATOM   2904 N N   . MET A 1 376 ? 220.081 235.269 156.185 1.00 54.47  ? 376  MET D N   1 
ATOM   2905 C CA  . MET A 1 376 ? 219.519 234.540 157.315 1.00 54.47  ? 376  MET D CA  1 
ATOM   2906 C C   . MET A 1 376 ? 218.421 233.586 156.867 1.00 54.47  ? 376  MET D C   1 
ATOM   2907 O O   . MET A 1 376 ? 218.235 232.533 157.481 1.00 54.47  ? 376  MET D O   1 
ATOM   2908 C CB  . MET A 1 376 ? 218.996 235.513 158.371 1.00 54.47  ? 376  MET D CB  1 
ATOM   2909 C CG  . MET A 1 376 ? 218.617 234.837 159.681 1.00 54.47  ? 376  MET D CG  1 
ATOM   2910 S SD  . MET A 1 376 ? 218.426 235.990 161.050 1.00 54.47  ? 376  MET D SD  1 
ATOM   2911 C CE  . MET A 1 376 ? 220.089 236.641 161.175 1.00 54.47  ? 376  MET D CE  1 
ATOM   2912 N N   . GLY A 1 377 ? 217.699 233.918 155.795 1.00 52.81  ? 377  GLY D N   1 
ATOM   2913 C CA  . GLY A 1 377 ? 216.777 232.952 155.218 1.00 52.81  ? 377  GLY D CA  1 
ATOM   2914 C C   . GLY A 1 377 ? 217.495 231.743 154.650 1.00 52.81  ? 377  GLY D C   1 
ATOM   2915 O O   . GLY A 1 377 ? 217.042 230.604 154.807 1.00 52.81  ? 377  GLY D O   1 
ATOM   2916 N N   . HIS A 1 378 ? 218.624 231.977 153.975 1.00 52.25  ? 378  HIS D N   1 
ATOM   2917 C CA  . HIS A 1 378 ? 219.462 230.865 153.529 1.00 52.25  ? 378  HIS D CA  1 
ATOM   2918 C C   . HIS A 1 378 ? 219.893 229.996 154.708 1.00 52.25  ? 378  HIS D C   1 
ATOM   2919 O O   . HIS A 1 378 ? 219.840 228.760 154.642 1.00 52.25  ? 378  HIS D O   1 
ATOM   2920 C CB  . HIS A 1 378 ? 220.689 231.393 152.785 1.00 52.25  ? 378  HIS D CB  1 
ATOM   2921 C CG  . HIS A 1 378 ? 220.416 231.803 151.372 1.00 52.25  ? 378  HIS D CG  1 
ATOM   2922 N ND1 . HIS A 1 378 ? 219.141 231.948 150.870 1.00 52.25  ? 378  HIS D ND1 1 
ATOM   2923 C CD2 . HIS A 1 378 ? 221.258 232.094 150.352 1.00 52.25  ? 378  HIS D CD2 1 
ATOM   2924 C CE1 . HIS A 1 378 ? 219.210 232.314 149.602 1.00 52.25  ? 378  HIS D CE1 1 
ATOM   2925 N NE2 . HIS A 1 378 ? 220.482 232.408 149.263 1.00 52.25  ? 378  HIS D NE2 1 
ATOM   2926 N N   . ILE A 1 379 ? 220.326 230.632 155.798 1.00 52.50  ? 379  ILE D N   1 
ATOM   2927 C CA  . ILE A 1 379 ? 220.778 229.888 156.971 1.00 52.50  ? 379  ILE D CA  1 
ATOM   2928 C C   . ILE A 1 379 ? 219.625 229.109 157.595 1.00 52.50  ? 379  ILE D C   1 
ATOM   2929 O O   . ILE A 1 379 ? 219.807 227.985 158.077 1.00 52.50  ? 379  ILE D O   1 
ATOM   2930 C CB  . ILE A 1 379 ? 221.437 230.844 157.984 1.00 52.50  ? 379  ILE D CB  1 
ATOM   2931 C CG1 . ILE A 1 379 ? 222.734 231.410 157.408 1.00 52.50  ? 379  ILE D CG1 1 
ATOM   2932 C CG2 . ILE A 1 379 ? 221.718 230.133 159.298 1.00 52.50  ? 379  ILE D CG2 1 
ATOM   2933 C CD1 . ILE A 1 379 ? 223.792 230.361 157.148 1.00 52.50  ? 379  ILE D CD1 1 
ATOM   2934 N N   . GLN A 1 380 ? 218.424 229.690 157.599 1.00 51.09  ? 380  GLN D N   1 
ATOM   2935 C CA  . GLN A 1 380 ? 217.261 228.988 158.129 1.00 51.09  ? 380  GLN D CA  1 
ATOM   2936 C C   . GLN A 1 380 ? 216.924 227.767 157.285 1.00 51.09  ? 380  GLN D C   1 
ATOM   2937 O O   . GLN A 1 380 ? 216.601 226.704 157.826 1.00 51.09  ? 380  GLN D O   1 
ATOM   2938 C CB  . GLN A 1 380 ? 216.064 229.935 158.205 1.00 51.09  ? 380  GLN D CB  1 
ATOM   2939 C CG  . GLN A 1 380 ? 216.153 230.973 159.313 1.00 51.09  ? 380  GLN D CG  1 
ATOM   2940 C CD  . GLN A 1 380 ? 215.951 230.377 160.692 1.00 51.09  ? 380  GLN D CD  1 
ATOM   2941 O OE1 . GLN A 1 380 ? 215.478 229.250 160.832 1.00 51.09  ? 380  GLN D OE1 1 
ATOM   2942 N NE2 . GLN A 1 380 ? 216.308 231.136 161.721 1.00 51.09  ? 380  GLN D NE2 1 
ATOM   2943 N N   . TYR A 1 381 ? 216.995 227.899 155.958 1.00 51.83  ? 381  TYR D N   1 
ATOM   2944 C CA  . TYR A 1 381 ? 216.802 226.740 155.090 1.00 51.83  ? 381  TYR D CA  1 
ATOM   2945 C C   . TYR A 1 381 ? 217.841 225.661 155.383 1.00 51.83  ? 381  TYR D C   1 
ATOM   2946 O O   . TYR A 1 381 ? 217.513 224.466 155.450 1.00 51.83  ? 381  TYR D O   1 
ATOM   2947 C CB  . TYR A 1 381 ? 216.869 227.175 153.624 1.00 51.83  ? 381  TYR D CB  1 
ATOM   2948 C CG  . TYR A 1 381 ? 216.179 226.248 152.641 1.00 51.83  ? 381  TYR D CG  1 
ATOM   2949 C CD1 . TYR A 1 381 ? 215.739 224.988 153.023 1.00 51.83  ? 381  TYR D CD1 1 
ATOM   2950 C CD2 . TYR A 1 381 ? 215.970 226.640 151.325 1.00 51.83  ? 381  TYR D CD2 1 
ATOM   2951 C CE1 . TYR A 1 381 ? 215.114 224.145 152.125 1.00 51.83  ? 381  TYR D CE1 1 
ATOM   2952 C CE2 . TYR A 1 381 ? 215.344 225.805 150.420 1.00 51.83  ? 381  TYR D CE2 1 
ATOM   2953 C CZ  . TYR A 1 381 ? 214.918 224.559 150.825 1.00 51.83  ? 381  TYR D CZ  1 
ATOM   2954 O OH  . TYR A 1 381 ? 214.294 223.724 149.928 1.00 51.83  ? 381  TYR D OH  1 
ATOM   2955 N N   . ASP A 1 382 ? 219.101 226.067 155.559 1.00 53.04  ? 382  ASP D N   1 
ATOM   2956 C CA  . ASP A 1 382 ? 220.160 225.109 155.866 1.00 53.04  ? 382  ASP D CA  1 
ATOM   2957 C C   . ASP A 1 382 ? 219.871 224.370 157.167 1.00 53.04  ? 382  ASP D C   1 
ATOM   2958 O O   . ASP A 1 382 ? 219.961 223.138 157.229 1.00 53.04  ? 382  ASP D O   1 
ATOM   2959 C CB  . ASP A 1 382 ? 221.510 225.824 155.943 1.00 53.04  ? 382  ASP D CB  1 
ATOM   2960 C CG  . ASP A 1 382 ? 221.913 226.458 154.627 1.00 53.04  ? 382  ASP D CG  1 
ATOM   2961 O OD1 . ASP A 1 382 ? 221.528 225.927 153.566 1.00 53.04  ? 382  ASP D OD1 1 
ATOM   2962 O OD2 . ASP A 1 382 ? 222.618 227.488 154.654 1.00 53.04  ? 382  ASP D OD2 1 
ATOM   2963 N N   . MET A 1 383 ? 219.525 225.112 158.222 1.00 52.10  ? 383  MET D N   1 
ATOM   2964 C CA  . MET A 1 383 ? 219.217 224.483 159.502 1.00 52.10  ? 383  MET D CA  1 
ATOM   2965 C C   . MET A 1 383 ? 217.976 223.607 159.410 1.00 52.10  ? 383  MET D C   1 
ATOM   2966 O O   . MET A 1 383 ? 217.854 222.624 160.150 1.00 52.10  ? 383  MET D O   1 
ATOM   2967 C CB  . MET A 1 383 ? 219.027 225.544 160.586 1.00 52.10  ? 383  MET D CB  1 
ATOM   2968 C CG  . MET A 1 383 ? 220.238 226.424 160.829 1.00 52.10  ? 383  MET D CG  1 
ATOM   2969 S SD  . MET A 1 383 ? 220.045 227.454 162.295 1.00 52.10  ? 383  MET D SD  1 
ATOM   2970 C CE  . MET A 1 383 ? 218.425 228.155 161.998 1.00 52.10  ? 383  MET D CE  1 
ATOM   2971 N N   . ALA A 1 384 ? 217.048 223.945 158.515 1.00 53.37  ? 384  ALA D N   1 
ATOM   2972 C CA  . ALA A 1 384 ? 215.836 223.150 158.370 1.00 53.37  ? 384  ALA D CA  1 
ATOM   2973 C C   . ALA A 1 384 ? 216.135 221.807 157.718 1.00 53.37  ? 384  ALA D C   1 
ATOM   2974 O O   . ALA A 1 384 ? 215.655 220.764 158.179 1.00 53.37  ? 384  ALA D O   1 
ATOM   2975 C CB  . ALA A 1 384 ? 214.794 223.923 157.563 1.00 53.37  ? 384  ALA D CB  1 
ATOM   2976 N N   . TYR A 1 385 ? 216.927 221.805 156.647 1.00 54.42  ? 385  TYR D N   1 
ATOM   2977 C CA  . TYR A 1 385 ? 217.228 220.538 155.987 1.00 54.42  ? 385  TYR D CA  1 
ATOM   2978 C C   . TYR A 1 385 ? 218.453 219.835 156.564 1.00 54.42  ? 385  TYR D C   1 
ATOM   2979 O O   . TYR A 1 385 ? 218.831 218.773 156.059 1.00 54.42  ? 385  TYR D O   1 
ATOM   2980 C CB  . TYR A 1 385 ? 217.386 220.720 154.464 1.00 54.42  ? 385  TYR D CB  1 
ATOM   2981 C CG  . TYR A 1 385 ? 218.548 221.565 153.965 1.00 54.42  ? 385  TYR D CG  1 
ATOM   2982 C CD1 . TYR A 1 385 ? 219.867 221.190 154.190 1.00 54.42  ? 385  TYR D CD1 1 
ATOM   2983 C CD2 . TYR A 1 385 ? 218.318 222.702 153.204 1.00 54.42  ? 385  TYR D CD2 1 
ATOM   2984 C CE1 . TYR A 1 385 ? 220.918 221.950 153.718 1.00 54.42  ? 385  TYR D CE1 1 
ATOM   2985 C CE2 . TYR A 1 385 ? 219.362 223.468 152.727 1.00 54.42  ? 385  TYR D CE2 1 
ATOM   2986 C CZ  . TYR A 1 385 ? 220.660 223.086 152.985 1.00 54.42  ? 385  TYR D CZ  1 
ATOM   2987 O OH  . TYR A 1 385 ? 221.704 223.845 152.509 1.00 54.42  ? 385  TYR D OH  1 
ATOM   2988 N N   . ALA A 1 386 ? 219.080 220.392 157.604 1.00 53.34  ? 386  ALA D N   1 
ATOM   2989 C CA  . ALA A 1 386 ? 220.217 219.730 158.233 1.00 53.34  ? 386  ALA D CA  1 
ATOM   2990 C C   . ALA A 1 386 ? 219.859 218.408 158.903 1.00 53.34  ? 386  ALA D C   1 
ATOM   2991 O O   . ALA A 1 386 ? 220.768 217.639 159.231 1.00 53.34  ? 386  ALA D O   1 
ATOM   2992 C CB  . ALA A 1 386 ? 220.862 220.663 159.260 1.00 53.34  ? 386  ALA D CB  1 
ATOM   2993 N N   . ALA A 1 387 ? 218.574 218.124 159.116 1.00 53.29  ? 387  ALA D N   1 
ATOM   2994 C CA  . ALA A 1 387 ? 218.148 216.893 159.769 1.00 53.29  ? 387  ALA D CA  1 
ATOM   2995 C C   . ALA A 1 387 ? 218.044 215.711 158.809 1.00 53.29  ? 387  ALA D C   1 
ATOM   2996 O O   . ALA A 1 387 ? 217.381 214.720 159.136 1.00 53.29  ? 387  ALA D O   1 
ATOM   2997 C CB  . ALA A 1 387 ? 216.808 217.109 160.476 1.00 53.29  ? 387  ALA D CB  1 
ATOM   2998 N N   . GLN A 1 388 ? 218.681 215.789 157.643 1.00 54.67  ? 388  GLN D N   1 
ATOM   2999 C CA  . GLN A 1 388 ? 218.607 214.734 156.641 1.00 54.67  ? 388  GLN D CA  1 
ATOM   3000 C C   . GLN A 1 388 ? 220.009 214.238 156.302 1.00 54.67  ? 388  GLN D C   1 
ATOM   3001 O O   . GLN A 1 388 ? 220.996 214.865 156.709 1.00 54.67  ? 388  GLN D O   1 
ATOM   3002 C CB  . GLN A 1 388 ? 217.883 215.246 155.394 1.00 54.67  ? 388  GLN D CB  1 
ATOM   3003 C CG  . GLN A 1 388 ? 216.394 215.456 155.598 1.00 54.67  ? 388  GLN D CG  1 
ATOM   3004 C CD  . GLN A 1 388 ? 215.653 215.647 154.294 1.00 54.67  ? 388  GLN D CD  1 
ATOM   3005 O OE1 . GLN A 1 388 ? 216.262 215.751 153.229 1.00 54.67  ? 388  GLN D OE1 1 
ATOM   3006 N NE2 . GLN A 1 388 ? 214.328 215.689 154.367 1.00 54.67  ? 388  GLN D NE2 1 
ATOM   3007 N N   . PRO A 1 389 ? 220.146 213.119 155.587 1.00 54.15  ? 389  PRO D N   1 
ATOM   3008 C CA  . PRO A 1 389 ? 221.481 212.646 155.196 1.00 54.15  ? 389  PRO D CA  1 
ATOM   3009 C C   . PRO A 1 389 ? 222.248 213.688 154.393 1.00 54.15  ? 389  PRO D C   1 
ATOM   3010 O O   . PRO A 1 389 ? 221.704 214.682 153.907 1.00 54.15  ? 389  PRO D O   1 
ATOM   3011 C CB  . PRO A 1 389 ? 221.182 211.401 154.357 1.00 54.15  ? 389  PRO D CB  1 
ATOM   3012 C CG  . PRO A 1 389 ? 219.905 210.891 154.915 1.00 54.15  ? 389  PRO D CG  1 
ATOM   3013 C CD  . PRO A 1 389 ? 219.109 212.109 155.300 1.00 54.15  ? 389  PRO D CD  1 
ATOM   3014 N N   . PHE A 1 390 ? 223.551 213.433 154.253 1.00 53.34  ? 390  PHE D N   1 
ATOM   3015 C CA  . PHE A 1 390 ? 224.448 214.409 153.640 1.00 53.34  ? 390  PHE D CA  1 
ATOM   3016 C C   . PHE A 1 390 ? 224.083 214.665 152.183 1.00 53.34  ? 390  PHE D C   1 
ATOM   3017 O O   . PHE A 1 390 ? 224.004 215.819 151.745 1.00 53.34  ? 390  PHE D O   1 
ATOM   3018 C CB  . PHE A 1 390 ? 225.895 213.929 153.760 1.00 53.34  ? 390  PHE D CB  1 
ATOM   3019 C CG  . PHE A 1 390 ? 226.900 214.874 153.165 1.00 53.34  ? 390  PHE D CG  1 
ATOM   3020 C CD1 . PHE A 1 390 ? 227.348 215.970 153.883 1.00 53.34  ? 390  PHE D CD1 1 
ATOM   3021 C CD2 . PHE A 1 390 ? 227.403 214.662 151.893 1.00 53.34  ? 390  PHE D CD2 1 
ATOM   3022 C CE1 . PHE A 1 390 ? 228.273 216.840 153.340 1.00 53.34  ? 390  PHE D CE1 1 
ATOM   3023 C CE2 . PHE A 1 390 ? 228.329 215.528 151.345 1.00 53.34  ? 390  PHE D CE2 1 
ATOM   3024 C CZ  . PHE A 1 390 ? 228.764 216.619 152.069 1.00 53.34  ? 390  PHE D CZ  1 
ATOM   3025 N N   . LEU A 1 391 ? 223.858 213.598 151.413 1.00 53.80  ? 391  LEU D N   1 
ATOM   3026 C CA  . LEU A 1 391 ? 223.556 213.756 149.995 1.00 53.80  ? 391  LEU D CA  1 
ATOM   3027 C C   . LEU A 1 391 ? 222.211 214.428 149.755 1.00 53.80  ? 391  LEU D C   1 
ATOM   3028 O O   . LEU A 1 391 ? 221.968 214.917 148.646 1.00 53.80  ? 391  LEU D O   1 
ATOM   3029 C CB  . LEU A 1 391 ? 223.590 212.396 149.297 1.00 53.80  ? 391  LEU D CB  1 
ATOM   3030 C CG  . LEU A 1 391 ? 224.969 211.745 149.186 1.00 53.80  ? 391  LEU D CG  1 
ATOM   3031 C CD1 . LEU A 1 391 ? 224.863 210.360 148.570 1.00 53.80  ? 391  LEU D CD1 1 
ATOM   3032 C CD2 . LEU A 1 391 ? 225.904 212.625 148.372 1.00 53.80  ? 391  LEU D CD2 1 
ATOM   3033 N N   . LEU A 1 392 ? 221.339 214.467 150.758 1.00 52.37  ? 392  LEU D N   1 
ATOM   3034 C CA  . LEU A 1 392 ? 220.036 215.103 150.633 1.00 52.37  ? 392  LEU D CA  1 
ATOM   3035 C C   . LEU A 1 392 ? 219.973 216.465 151.309 1.00 52.37  ? 392  LEU D C   1 
ATOM   3036 O O   . LEU A 1 392 ? 218.940 217.135 151.224 1.00 52.37  ? 392  LEU D O   1 
ATOM   3037 C CB  . LEU A 1 392 ? 218.948 214.190 151.207 1.00 52.37  ? 392  LEU D CB  1 
ATOM   3038 C CG  . LEU A 1 392 ? 218.855 212.800 150.577 1.00 52.37  ? 392  LEU D CG  1 
ATOM   3039 C CD1 . LEU A 1 392 ? 217.708 212.015 151.187 1.00 52.37  ? 392  LEU D CD1 1 
ATOM   3040 C CD2 . LEU A 1 392 ? 218.699 212.901 149.068 1.00 52.37  ? 392  LEU D CD2 1 
ATOM   3041 N N   . ARG A 1 393 ? 221.047 216.892 151.975 1.00 53.67  ? 393  ARG D N   1 
ATOM   3042 C CA  . ARG A 1 393 ? 221.090 218.204 152.622 1.00 53.67  ? 393  ARG D CA  1 
ATOM   3043 C C   . ARG A 1 393 ? 221.303 219.284 151.560 1.00 53.67  ? 393  ARG D C   1 
ATOM   3044 O O   . ARG A 1 393 ? 222.377 219.870 151.412 1.00 53.67  ? 393  ARG D O   1 
ATOM   3045 C CB  . ARG A 1 393 ? 222.174 218.244 153.690 1.00 53.67  ? 393  ARG D CB  1 
ATOM   3046 C CG  . ARG A 1 393 ? 221.721 217.739 155.049 1.00 53.67  ? 393  ARG D CG  1 
ATOM   3047 C CD  . ARG A 1 393 ? 222.734 218.072 156.131 1.00 53.67  ? 393  ARG D CD  1 
ATOM   3048 N NE  . ARG A 1 393 ? 223.875 217.164 156.122 1.00 53.67  ? 393  ARG D NE  1 
ATOM   3049 C CZ  . ARG A 1 393 ? 223.978 216.091 156.899 1.00 53.67  ? 393  ARG D CZ  1 
ATOM   3050 N NH1 . ARG A 1 393 ? 225.051 215.318 156.827 1.00 53.67  ? 393  ARG D NH1 1 
ATOM   3051 N NH2 . ARG A 1 393 ? 223.007 215.792 157.750 1.00 53.67  ? 393  ARG D NH2 1 
ATOM   3052 N N   . ASN A 1 394 ? 220.233 219.545 150.813 1.00 54.73  ? 394  ASN D N   1 
ATOM   3053 C CA  . ASN A 1 394 ? 220.249 220.545 149.756 1.00 54.73  ? 394  ASN D CA  1 
ATOM   3054 C C   . ASN A 1 394 ? 218.809 220.887 149.408 1.00 54.73  ? 394  ASN D C   1 
ATOM   3055 O O   . ASN A 1 394 ? 217.876 220.168 149.776 1.00 54.73  ? 394  ASN D O   1 
ATOM   3056 C CB  . ASN A 1 394 ? 221.008 220.045 148.521 1.00 54.73  ? 394  ASN D CB  1 
ATOM   3057 C CG  . ASN A 1 394 ? 221.427 221.170 147.594 1.00 54.73  ? 394  ASN D CG  1 
ATOM   3058 O OD1 . ASN A 1 394 ? 220.784 222.218 147.539 1.00 54.73  ? 394  ASN D OD1 1 
ATOM   3059 N ND2 . ASN A 1 394 ? 222.511 220.956 146.858 1.00 54.73  ? 394  ASN D ND2 1 
ATOM   3060 N N   . GLY A 1 395 ? 218.640 222.001 148.699 1.00 53.70  ? 395  GLY D N   1 
ATOM   3061 C CA  . GLY A 1 395 ? 217.314 222.412 148.285 1.00 53.70  ? 395  GLY D CA  1 
ATOM   3062 C C   . GLY A 1 395 ? 216.674 221.416 147.338 1.00 53.70  ? 395  GLY D C   1 
ATOM   3063 O O   . GLY A 1 395 ? 217.343 220.650 146.642 1.00 53.70  ? 395  GLY D O   1 
ATOM   3064 N N   . ALA A 1 396 ? 215.339 221.431 147.321 1.00 53.63  ? 396  ALA D N   1 
ATOM   3065 C CA  . ALA A 1 396 ? 214.596 220.537 146.440 1.00 53.63  ? 396  ALA D CA  1 
ATOM   3066 C C   . ALA A 1 396 ? 214.885 220.808 144.971 1.00 53.63  ? 396  ALA D C   1 
ATOM   3067 O O   . ALA A 1 396 ? 214.727 219.907 144.141 1.00 53.63  ? 396  ALA D O   1 
ATOM   3068 C CB  . ALA A 1 396 ? 213.095 220.661 146.707 1.00 53.63  ? 396  ALA D CB  1 
ATOM   3069 N N   . ASN A 1 397 ? 215.305 222.024 144.635 1.00 55.78  ? 397  ASN D N   1 
ATOM   3070 C CA  . ASN A 1 397 ? 215.663 222.374 143.271 1.00 55.78  ? 397  ASN D CA  1 
ATOM   3071 C C   . ASN A 1 397 ? 216.723 223.465 143.328 1.00 55.78  ? 397  ASN D C   1 
ATOM   3072 O O   . ASN A 1 397 ? 217.001 224.035 144.386 1.00 55.78  ? 397  ASN D O   1 
ATOM   3073 C CB  . ASN A 1 397 ? 214.434 222.820 142.470 1.00 55.78  ? 397  ASN D CB  1 
ATOM   3074 C CG  . ASN A 1 397 ? 214.690 222.857 140.980 1.00 55.78  ? 397  ASN D CG  1 
ATOM   3075 O OD1 . ASN A 1 397 ? 215.114 223.877 140.437 1.00 55.78  ? 397  ASN D OD1 1 
ATOM   3076 N ND2 . ASN A 1 397 ? 214.438 221.740 140.309 1.00 55.78  ? 397  ASN D ND2 1 
ATOM   3077 N N   . GLU A 1 398 ? 217.318 223.752 142.175 1.00 55.19  ? 398  GLU D N   1 
ATOM   3078 C CA  . GLU A 1 398 ? 218.377 224.755 142.099 1.00 55.19  ? 398  GLU D CA  1 
ATOM   3079 C C   . GLU A 1 398 ? 217.867 226.188 142.254 1.00 55.19  ? 398  GLU D C   1 
ATOM   3080 O O   . GLU A 1 398 ? 218.672 227.116 142.095 1.00 55.19  ? 398  GLU D O   1 
ATOM   3081 C CB  . GLU A 1 398 ? 219.133 224.612 140.777 1.00 55.19  ? 398  GLU D CB  1 
ATOM   3082 C CG  . GLU A 1 398 ? 218.264 224.768 139.542 1.00 55.19  ? 398  GLU D CG  1 
ATOM   3083 C CD  . GLU A 1 398 ? 219.049 224.603 138.257 1.00 55.19  ? 398  GLU D CD  1 
ATOM   3084 O OE1 . GLU A 1 398 ? 220.235 224.218 138.328 1.00 55.19  ? 398  GLU D OE1 1 
ATOM   3085 O OE2 . GLU A 1 398 ? 218.483 224.861 137.174 1.00 55.19  ? 398  GLU D OE2 1 
ATOM   3086 N N   . GLY A 1 399 ? 216.590 226.413 142.553 1.00 53.22  ? 399  GLY D N   1 
ATOM   3087 C CA  . GLY A 1 399 ? 216.079 227.760 142.710 1.00 53.22  ? 399  GLY D CA  1 
ATOM   3088 C C   . GLY A 1 399 ? 215.260 227.957 143.968 1.00 53.22  ? 399  GLY D C   1 
ATOM   3089 O O   . GLY A 1 399 ? 214.651 229.014 144.160 1.00 53.22  ? 399  GLY D O   1 
ATOM   3090 N N   . PHE A 1 400 ? 215.235 226.945 144.838 1.00 53.92  ? 400  PHE D N   1 
ATOM   3091 C CA  . PHE A 1 400 ? 214.449 227.043 146.064 1.00 53.92  ? 400  PHE D CA  1 
ATOM   3092 C C   . PHE A 1 400 ? 215.145 227.893 147.120 1.00 53.92  ? 400  PHE D C   1 
ATOM   3093 O O   . PHE A 1 400 ? 214.488 228.664 147.827 1.00 53.92  ? 400  PHE D O   1 
ATOM   3094 C CB  . PHE A 1 400 ? 214.156 225.646 146.612 1.00 53.92  ? 400  PHE D CB  1 
ATOM   3095 C CG  . PHE A 1 400 ? 212.872 225.055 146.106 1.00 53.92  ? 400  PHE D CG  1 
ATOM   3096 C CD1 . PHE A 1 400 ? 212.715 224.748 144.767 1.00 53.92  ? 400  PHE D CD1 1 
ATOM   3097 C CD2 . PHE A 1 400 ? 211.822 224.804 146.972 1.00 53.92  ? 400  PHE D CD2 1 
ATOM   3098 C CE1 . PHE A 1 400 ? 211.535 224.203 144.299 1.00 53.92  ? 400  PHE D CE1 1 
ATOM   3099 C CE2 . PHE A 1 400 ? 210.639 224.259 146.511 1.00 53.92  ? 400  PHE D CE2 1 
ATOM   3100 C CZ  . PHE A 1 400 ? 210.496 223.958 145.172 1.00 53.92  ? 400  PHE D CZ  1 
ATOM   3101 N N   . HIS A 1 401 ? 216.469 227.768 147.241 1.00 52.32  ? 401  HIS D N   1 
ATOM   3102 C CA  . HIS A 1 401 ? 217.202 228.541 148.240 1.00 52.32  ? 401  HIS D CA  1 
ATOM   3103 C C   . HIS A 1 401 ? 217.078 230.037 147.978 1.00 52.32  ? 401  HIS D C   1 
ATOM   3104 O O   . HIS A 1 401 ? 216.746 230.817 148.881 1.00 52.32  ? 401  HIS D O   1 
ATOM   3105 C CB  . HIS A 1 401 ? 218.672 228.117 148.247 1.00 52.32  ? 401  HIS D CB  1 
ATOM   3106 C CG  . HIS A 1 401 ? 219.136 227.560 149.555 1.00 52.32  ? 401  HIS D CG  1 
ATOM   3107 N ND1 . HIS A 1 401 ? 219.432 228.356 150.640 1.00 52.32  ? 401  HIS D ND1 1 
ATOM   3108 C CD2 . HIS A 1 401 ? 219.362 226.285 149.951 1.00 52.32  ? 401  HIS D CD2 1 
ATOM   3109 C CE1 . HIS A 1 401 ? 219.817 227.596 151.649 1.00 52.32  ? 401  HIS D CE1 1 
ATOM   3110 N NE2 . HIS A 1 401 ? 219.784 226.335 151.258 1.00 52.32  ? 401  HIS D NE2 1 
ATOM   3111 N N   . GLU A 1 402 ? 217.343 230.454 146.738 1.00 53.71  ? 402  GLU D N   1 
ATOM   3112 C CA  . GLU A 1 402 ? 217.258 231.869 146.401 1.00 53.71  ? 402  GLU D CA  1 
ATOM   3113 C C   . GLU A 1 402 ? 215.835 232.390 146.539 1.00 53.71  ? 402  GLU D C   1 
ATOM   3114 O O   . GLU A 1 402 ? 215.635 233.541 146.937 1.00 53.71  ? 402  GLU D O   1 
ATOM   3115 C CB  . GLU A 1 402 ? 217.780 232.103 144.983 1.00 53.71  ? 402  GLU D CB  1 
ATOM   3116 C CG  . GLU A 1 402 ? 218.144 233.548 144.687 1.00 53.71  ? 402  GLU D CG  1 
ATOM   3117 C CD  . GLU A 1 402 ? 219.399 233.999 145.411 1.00 53.71  ? 402  GLU D CD  1 
ATOM   3118 O OE1 . GLU A 1 402 ? 220.165 233.131 145.880 1.00 53.71  ? 402  GLU D OE1 1 
ATOM   3119 O OE2 . GLU A 1 402 ? 219.621 235.224 145.510 1.00 53.71  ? 402  GLU D OE2 1 
ATOM   3120 N N   . ALA A 1 403 ? 214.836 231.557 146.237 1.00 52.34  ? 403  ALA D N   1 
ATOM   3121 C CA  . ALA A 1 403 ? 213.450 231.980 146.410 1.00 52.34  ? 403  ALA D CA  1 
ATOM   3122 C C   . ALA A 1 403 ? 213.110 232.175 147.883 1.00 52.34  ? 403  ALA D C   1 
ATOM   3123 O O   . ALA A 1 403 ? 212.440 233.149 148.247 1.00 52.34  ? 403  ALA D O   1 
ATOM   3124 C CB  . ALA A 1 403 ? 212.506 230.963 145.769 1.00 52.34  ? 403  ALA D CB  1 
ATOM   3125 N N   . VAL A 1 404 ? 213.558 231.256 148.743 1.00 52.43  ? 404  VAL D N   1 
ATOM   3126 C CA  . VAL A 1 404 ? 213.304 231.388 150.174 1.00 52.43  ? 404  VAL D CA  1 
ATOM   3127 C C   . VAL A 1 404 ? 214.015 232.613 150.738 1.00 52.43  ? 404  VAL D C   1 
ATOM   3128 O O   . VAL A 1 404 ? 213.510 233.265 151.660 1.00 52.43  ? 404  VAL D O   1 
ATOM   3129 C CB  . VAL A 1 404 ? 213.717 230.097 150.906 1.00 52.43  ? 404  VAL D CB  1 
ATOM   3130 C CG1 . VAL A 1 404 ? 213.652 230.280 152.415 1.00 52.43  ? 404  VAL D CG1 1 
ATOM   3131 C CG2 . VAL A 1 404 ? 212.821 228.947 150.481 1.00 52.43  ? 404  VAL D CG2 1 
ATOM   3132 N N   . GLY A 1 405 ? 215.184 232.956 150.197 1.00 52.91  ? 405  GLY D N   1 
ATOM   3133 C CA  . GLY A 1 405 ? 215.842 234.179 150.630 1.00 52.91  ? 405  GLY D CA  1 
ATOM   3134 C C   . GLY A 1 405 ? 215.131 235.430 150.143 1.00 52.91  ? 405  GLY D C   1 
ATOM   3135 O O   . GLY A 1 405 ? 214.969 236.402 150.892 1.00 52.91  ? 405  GLY D O   1 
ATOM   3136 N N   . GLU A 1 406 ? 214.677 235.417 148.888 1.00 54.95  ? 406  GLU D N   1 
ATOM   3137 C CA  . GLU A 1 406 ? 214.088 236.614 148.304 1.00 54.95  ? 406  GLU D CA  1 
ATOM   3138 C C   . GLU A 1 406 ? 212.693 236.890 148.847 1.00 54.95  ? 406  GLU D C   1 
ATOM   3139 O O   . GLU A 1 406 ? 212.290 238.054 148.927 1.00 54.95  ? 406  GLU D O   1 
ATOM   3140 C CB  . GLU A 1 406 ? 214.062 236.495 146.781 1.00 54.95  ? 406  GLU D CB  1 
ATOM   3141 C CG  . GLU A 1 406 ? 215.428 236.655 146.134 1.00 54.95  ? 406  GLU D CG  1 
ATOM   3142 C CD  . GLU A 1 406 ? 215.386 236.501 144.627 1.00 54.95  ? 406  GLU D CD  1 
ATOM   3143 O OE1 . GLU A 1 406 ? 214.332 236.092 144.100 1.00 54.95  ? 406  GLU D OE1 1 
ATOM   3144 O OE2 . GLU A 1 406 ? 216.408 236.788 143.970 1.00 54.95  ? 406  GLU D OE2 1 
ATOM   3145 N N   . ILE A 1 407 ? 211.943 235.856 149.237 1.00 53.63  ? 407  ILE D N   1 
ATOM   3146 C CA  . ILE A 1 407 ? 210.640 236.114 149.844 1.00 53.63  ? 407  ILE D CA  1 
ATOM   3147 C C   . ILE A 1 407 ? 210.810 236.831 151.178 1.00 53.63  ? 407  ILE D C   1 
ATOM   3148 O O   . ILE A 1 407 ? 210.044 237.743 151.511 1.00 53.63  ? 407  ILE D O   1 
ATOM   3149 C CB  . ILE A 1 407 ? 209.824 234.815 149.990 1.00 53.63  ? 407  ILE D CB  1 
ATOM   3150 C CG1 . ILE A 1 407 ? 210.571 233.777 150.827 1.00 53.63  ? 407  ILE D CG1 1 
ATOM   3151 C CG2 . ILE A 1 407 ? 209.482 234.248 148.629 1.00 53.63  ? 407  ILE D CG2 1 
ATOM   3152 C CD1 . ILE A 1 407 ? 209.796 232.496 151.039 1.00 53.63  ? 407  ILE D CD1 1 
ATOM   3153 N N   . MET A 1 408 ? 211.831 236.453 151.952 1.00 53.96  ? 408  MET D N   1 
ATOM   3154 C CA  . MET A 1 408 ? 212.118 237.166 153.191 1.00 53.96  ? 408  MET D CA  1 
ATOM   3155 C C   . MET A 1 408 ? 212.605 238.582 152.912 1.00 53.96  ? 408  MET D C   1 
ATOM   3156 O O   . MET A 1 408 ? 212.216 239.527 153.611 1.00 53.96  ? 408  MET D O   1 
ATOM   3157 C CB  . MET A 1 408 ? 213.150 236.399 154.016 1.00 53.96  ? 408  MET D CB  1 
ATOM   3158 C CG  . MET A 1 408 ? 212.549 235.422 155.010 1.00 53.96  ? 408  MET D CG  1 
ATOM   3159 S SD  . MET A 1 408 ? 211.632 234.076 154.245 1.00 53.96  ? 408  MET D SD  1 
ATOM   3160 C CE  . MET A 1 408 ? 211.118 233.166 155.698 1.00 53.96  ? 408  MET D CE  1 
ATOM   3161 N N   . SER A 1 409 ? 213.457 238.750 151.896 1.00 55.06  ? 409  SER D N   1 
ATOM   3162 C CA  . SER A 1 409 ? 213.917 240.091 151.545 1.00 55.06  ? 409  SER D CA  1 
ATOM   3163 C C   . SER A 1 409 ? 212.760 240.988 151.118 1.00 55.06  ? 409  SER D C   1 
ATOM   3164 O O   . SER A 1 409 ? 212.783 242.197 151.376 1.00 55.06  ? 409  SER D O   1 
ATOM   3165 C CB  . SER A 1 409 ? 214.967 240.021 150.437 1.00 55.06  ? 409  SER D CB  1 
ATOM   3166 O OG  . SER A 1 409 ? 214.375 239.689 149.194 1.00 55.06  ? 409  SER D OG  1 
ATOM   3167 N N   . LEU A 1 410 ? 211.742 240.419 150.469 1.00 55.91  ? 410  LEU D N   1 
ATOM   3168 C CA  . LEU A 1 410 ? 210.583 241.204 150.060 1.00 55.91  ? 410  LEU D CA  1 
ATOM   3169 C C   . LEU A 1 410 ? 209.661 241.500 151.236 1.00 55.91  ? 410  LEU D C   1 
ATOM   3170 O O   . LEU A 1 410 ? 209.126 242.609 151.344 1.00 55.91  ? 410  LEU D O   1 
ATOM   3171 C CB  . LEU A 1 410 ? 209.814 240.476 148.956 1.00 55.91  ? 410  LEU D CB  1 
ATOM   3172 C CG  . LEU A 1 410 ? 210.487 240.389 147.585 1.00 55.91  ? 410  LEU D CG  1 
ATOM   3173 C CD1 . LEU A 1 410 ? 209.614 239.613 146.612 1.00 55.91  ? 410  LEU D CD1 1 
ATOM   3174 C CD2 . LEU A 1 410 ? 210.792 241.778 147.048 1.00 55.91  ? 410  LEU D CD2 1 
ATOM   3175 N N   . SER A 1 411 ? 209.458 240.522 152.123 1.00 56.49  ? 411  SER D N   1 
ATOM   3176 C CA  . SER A 1 411 ? 208.594 240.745 153.277 1.00 56.49  ? 411  SER D CA  1 
ATOM   3177 C C   . SER A 1 411 ? 209.218 241.719 154.269 1.00 56.49  ? 411  SER D C   1 
ATOM   3178 O O   . SER A 1 411 ? 208.495 242.377 155.025 1.00 56.49  ? 411  SER D O   1 
ATOM   3179 C CB  . SER A 1 411 ? 208.281 239.417 153.965 1.00 56.49  ? 411  SER D CB  1 
ATOM   3180 O OG  . SER A 1 411 ? 207.612 238.533 153.083 1.00 56.49  ? 411  SER D OG  1 
ATOM   3181 N N   . ALA A 1 412 ? 210.548 241.828 154.282 1.00 56.12  ? 412  ALA D N   1 
ATOM   3182 C CA  . ALA A 1 412 ? 211.212 242.747 155.196 1.00 56.12  ? 412  ALA D CA  1 
ATOM   3183 C C   . ALA A 1 412 ? 211.266 244.174 154.668 1.00 56.12  ? 412  ALA D C   1 
ATOM   3184 O O   . ALA A 1 412 ? 211.480 245.103 155.455 1.00 56.12  ? 412  ALA D O   1 
ATOM   3185 C CB  . ALA A 1 412 ? 212.630 242.260 155.497 1.00 56.12  ? 412  ALA D CB  1 
ATOM   3186 N N   . ALA A 1 413 ? 211.080 244.372 153.366 1.00 56.08  ? 413  ALA D N   1 
ATOM   3187 C CA  . ALA A 1 413 ? 211.167 245.694 152.759 1.00 56.08  ? 413  ALA D CA  1 
ATOM   3188 C C   . ALA A 1 413 ? 209.828 246.417 152.702 1.00 56.08  ? 413  ALA D C   1 
ATOM   3189 O O   . ALA A 1 413 ? 209.757 247.510 152.131 1.00 56.08  ? 413  ALA D O   1 
ATOM   3190 C CB  . ALA A 1 413 ? 211.752 245.588 151.348 1.00 56.08  ? 413  ALA D CB  1 
ATOM   3191 N N   . THR A 1 414 ? 208.774 245.844 153.272 1.00 57.89  ? 414  THR D N   1 
ATOM   3192 C CA  . THR A 1 414 ? 207.472 246.491 153.231 1.00 57.89  ? 414  THR D CA  1 
ATOM   3193 C C   . THR A 1 414 ? 207.437 247.663 154.210 1.00 57.89  ? 414  THR D C   1 
ATOM   3194 O O   . THR A 1 414 ? 208.057 247.601 155.276 1.00 57.89  ? 414  THR D O   1 
ATOM   3195 C CB  . THR A 1 414 ? 206.363 245.496 153.572 1.00 57.89  ? 414  THR D CB  1 
ATOM   3196 O OG1 . THR A 1 414 ? 206.579 244.968 154.886 1.00 57.89  ? 414  THR D OG1 1 
ATOM   3197 C CG2 . THR A 1 414 ? 206.349 244.353 152.569 1.00 57.89  ? 414  THR D CG2 1 
ATOM   3198 N N   . PRO A 1 415 ? 206.733 248.747 153.874 1.00 57.25  ? 415  PRO D N   1 
ATOM   3199 C CA  . PRO A 1 415 ? 206.654 249.884 154.807 1.00 57.25  ? 415  PRO D CA  1 
ATOM   3200 C C   . PRO A 1 415 ? 206.013 249.528 156.135 1.00 57.25  ? 415  PRO D C   1 
ATOM   3201 O O   . PRO A 1 415 ? 206.374 250.115 157.164 1.00 57.25  ? 415  PRO D O   1 
ATOM   3202 C CB  . PRO A 1 415 ? 205.816 250.913 154.033 1.00 57.25  ? 415  PRO D CB  1 
ATOM   3203 C CG  . PRO A 1 415 ? 205.962 250.525 152.597 1.00 57.25  ? 415  PRO D CG  1 
ATOM   3204 C CD  . PRO A 1 415 ? 206.062 249.031 152.595 1.00 57.25  ? 415  PRO D CD  1 
ATOM   3205 N N   . LYS A 1 416 ? 205.072 248.582 156.145 1.00 57.79  ? 416  LYS D N   1 
ATOM   3206 C CA  . LYS A 1 416 ? 204.457 248.154 157.398 1.00 57.79  ? 416  LYS D CA  1 
ATOM   3207 C C   . LYS A 1 416 ? 205.490 247.530 158.328 1.00 57.79  ? 416  LYS D C   1 
ATOM   3208 O O   . LYS A 1 416 ? 205.550 247.855 159.519 1.00 57.79  ? 416  LYS D O   1 
ATOM   3209 C CB  . LYS A 1 416 ? 203.322 247.171 157.110 1.00 57.79  ? 416  LYS D CB  1 
ATOM   3210 C CG  . LYS A 1 416 ? 202.677 246.581 158.351 1.00 57.79  ? 416  LYS D CG  1 
ATOM   3211 C CD  . LYS A 1 416 ? 201.616 245.557 157.982 1.00 57.79  ? 416  LYS D CD  1 
ATOM   3212 C CE  . LYS A 1 416 ? 200.987 244.943 159.221 1.00 57.79  ? 416  LYS D CE  1 
ATOM   3213 N NZ  . LYS A 1 416 ? 199.949 243.933 158.873 1.00 57.79  ? 416  LYS D NZ  1 
ATOM   3214 N N   . HIS A 1 417 ? 206.322 246.632 157.795 1.00 58.02  ? 417  HIS D N   1 
ATOM   3215 C CA  . HIS A 1 417 ? 207.362 246.013 158.610 1.00 58.02  ? 417  HIS D CA  1 
ATOM   3216 C C   . HIS A 1 417 ? 208.381 247.045 159.076 1.00 58.02  ? 417  HIS D C   1 
ATOM   3217 O O   . HIS A 1 417 ? 208.867 246.981 160.212 1.00 58.02  ? 417  HIS D O   1 
ATOM   3218 C CB  . HIS A 1 417 ? 208.045 244.895 157.822 1.00 58.02  ? 417  HIS D CB  1 
ATOM   3219 C CG  . HIS A 1 417 ? 209.016 244.091 158.629 1.00 58.02  ? 417  HIS D CG  1 
ATOM   3220 N ND1 . HIS A 1 417 ? 208.634 243.336 159.717 1.00 58.02  ? 417  HIS D ND1 1 
ATOM   3221 C CD2 . HIS A 1 417 ? 210.353 243.920 158.504 1.00 58.02  ? 417  HIS D CD2 1 
ATOM   3222 C CE1 . HIS A 1 417 ? 209.694 242.736 160.228 1.00 58.02  ? 417  HIS D CE1 1 
ATOM   3223 N NE2 . HIS A 1 417 ? 210.750 243.074 159.510 1.00 58.02  ? 417  HIS D NE2 1 
ATOM   3224 N N   . LEU A 1 418 ? 208.705 248.014 158.216 1.00 59.18  ? 418  LEU D N   1 
ATOM   3225 C CA  . LEU A 1 418 ? 209.679 249.037 158.584 1.00 59.18  ? 418  LEU D CA  1 
ATOM   3226 C C   . LEU A 1 418 ? 209.155 249.927 159.704 1.00 59.18  ? 418  LEU D C   1 
ATOM   3227 O O   . LEU A 1 418 ? 209.902 250.277 160.625 1.00 59.18  ? 418  LEU D O   1 
ATOM   3228 C CB  . LEU A 1 418 ? 210.050 249.875 157.361 1.00 59.18  ? 418  LEU D CB  1 
ATOM   3229 C CG  . LEU A 1 418 ? 210.830 249.157 156.259 1.00 59.18  ? 418  LEU D CG  1 
ATOM   3230 C CD1 . LEU A 1 418 ? 211.132 250.106 155.110 1.00 59.18  ? 418  LEU D CD1 1 
ATOM   3231 C CD2 . LEU A 1 418 ? 212.112 248.558 156.814 1.00 59.18  ? 418  LEU D CD2 1 
ATOM   3232 N N   . LYS A 1 419 ? 207.876 250.307 159.647 1.00 61.79  ? 419  LYS D N   1 
ATOM   3233 C CA  . LYS A 1 419 ? 207.310 251.124 160.712 1.00 61.79  ? 419  LYS D CA  1 
ATOM   3234 C C   . LYS A 1 419 ? 207.008 250.317 161.967 1.00 61.79  ? 419  LYS D C   1 
ATOM   3235 O O   . LYS A 1 419 ? 206.905 250.901 163.051 1.00 61.79  ? 419  LYS D O   1 
ATOM   3236 C CB  . LYS A 1 419 ? 206.041 251.834 160.231 1.00 61.79  ? 419  LYS D CB  1 
ATOM   3237 C CG  . LYS A 1 419 ? 204.868 250.917 159.944 1.00 61.79  ? 419  LYS D CG  1 
ATOM   3238 C CD  . LYS A 1 419 ? 203.629 251.716 159.576 1.00 61.79  ? 419  LYS D CD  1 
ATOM   3239 C CE  . LYS A 1 419 ? 203.891 252.625 158.387 1.00 61.79  ? 419  LYS D CE  1 
ATOM   3240 N NZ  . LYS A 1 419 ? 202.694 253.434 158.032 1.00 61.79  ? 419  LYS D NZ  1 
ATOM   3241 N N   . SER A 1 420 ? 206.864 248.994 161.850 1.00 60.73  ? 420  SER D N   1 
ATOM   3242 C CA  . SER A 1 420 ? 206.721 248.165 163.040 1.00 60.73  ? 420  SER D CA  1 
ATOM   3243 C C   . SER A 1 420 ? 208.057 247.934 163.732 1.00 60.73  ? 420  SER D C   1 
ATOM   3244 O O   . SER A 1 420 ? 208.097 247.791 164.959 1.00 60.73  ? 420  SER D O   1 
ATOM   3245 C CB  . SER A 1 420 ? 206.077 246.826 162.678 1.00 60.73  ? 420  SER D CB  1 
ATOM   3246 O OG  . SER A 1 420 ? 206.922 246.066 161.833 1.00 60.73  ? 420  SER D OG  1 
ATOM   3247 N N   . ILE A 1 421 ? 209.153 247.889 162.971 1.00 60.23  ? 421  ILE D N   1 
ATOM   3248 C CA  . ILE A 1 421 ? 210.474 247.768 163.582 1.00 60.23  ? 421  ILE D CA  1 
ATOM   3249 C C   . ILE A 1 421 ? 210.836 249.051 164.320 1.00 60.23  ? 421  ILE D C   1 
ATOM   3250 O O   . ILE A 1 421 ? 211.260 249.021 165.481 1.00 60.23  ? 421  ILE D O   1 
ATOM   3251 C CB  . ILE A 1 421 ? 211.529 247.413 162.519 1.00 60.23  ? 421  ILE D CB  1 
ATOM   3252 C CG1 . ILE A 1 421 ? 211.330 245.981 162.021 1.00 60.23  ? 421  ILE D CG1 1 
ATOM   3253 C CG2 . ILE A 1 421 ? 212.932 247.594 163.076 1.00 60.23  ? 421  ILE D CG2 1 
ATOM   3254 C CD1 . ILE A 1 421 ? 212.350 245.555 160.989 1.00 60.23  ? 421  ILE D CD1 1 
ATOM   3255 N N   . GLY A 1 422 ? 210.674 250.193 163.659 1.00 60.18  ? 422  GLY D N   1 
ATOM   3256 C CA  . GLY A 1 422 ? 210.994 251.470 164.265 1.00 60.18  ? 422  GLY D CA  1 
ATOM   3257 C C   . GLY A 1 422 ? 211.804 252.370 163.356 1.00 60.18  ? 422  GLY D C   1 
ATOM   3258 O O   . GLY A 1 422 ? 212.099 253.516 163.707 1.00 60.18  ? 422  GLY D O   1 
ATOM   3259 N N   . LEU A 1 423 ? 212.172 251.859 162.180 1.00 61.17  ? 423  LEU D N   1 
ATOM   3260 C CA  . LEU A 1 423 ? 212.948 252.657 161.236 1.00 61.17  ? 423  LEU D CA  1 
ATOM   3261 C C   . LEU A 1 423 ? 212.082 253.722 160.577 1.00 61.17  ? 423  LEU D C   1 
ATOM   3262 O O   . LEU A 1 423 ? 212.467 254.895 160.507 1.00 61.17  ? 423  LEU D O   1 
ATOM   3263 C CB  . LEU A 1 423 ? 213.584 251.750 160.183 1.00 61.17  ? 423  LEU D CB  1 
ATOM   3264 C CG  . LEU A 1 423 ? 214.613 250.741 160.694 1.00 61.17  ? 423  LEU D CG  1 
ATOM   3265 C CD1 . LEU A 1 423 ? 215.102 249.851 159.564 1.00 61.17  ? 423  LEU D CD1 1 
ATOM   3266 C CD2 . LEU A 1 423 ? 215.777 251.460 161.355 1.00 61.17  ? 423  LEU D CD2 1 
ATOM   3267 N N   . LEU A 1 424 ? 210.908 253.334 160.089 1.00 65.83  ? 424  LEU D N   1 
ATOM   3268 C CA  . LEU A 1 424 ? 209.992 254.265 159.449 1.00 65.83  ? 424  LEU D CA  1 
ATOM   3269 C C   . LEU A 1 424 ? 209.070 254.887 160.490 1.00 65.83  ? 424  LEU D C   1 
ATOM   3270 O O   . LEU A 1 424 ? 208.648 254.222 161.440 1.00 65.83  ? 424  LEU D O   1 
ATOM   3271 C CB  . LEU A 1 424 ? 209.170 253.556 158.371 1.00 65.83  ? 424  LEU D CB  1 
ATOM   3272 C CG  . LEU A 1 424 ? 208.298 254.438 157.477 1.00 65.83  ? 424  LEU D CG  1 
ATOM   3273 C CD1 . LEU A 1 424 ? 209.153 255.441 156.719 1.00 65.83  ? 424  LEU D CD1 1 
ATOM   3274 C CD2 . LEU A 1 424 ? 207.483 253.588 156.516 1.00 65.83  ? 424  LEU D CD2 1 
ATOM   3275 N N   . SER A 1 425 ? 208.768 256.168 160.306 1.00 72.85  ? 425  SER D N   1 
ATOM   3276 C CA  . SER A 1 425 ? 207.919 256.871 161.255 1.00 72.85  ? 425  SER D CA  1 
ATOM   3277 C C   . SER A 1 425 ? 206.497 256.315 161.204 1.00 72.85  ? 425  SER D C   1 
ATOM   3278 O O   . SER A 1 425 ? 206.008 255.956 160.129 1.00 72.85  ? 425  SER D O   1 
ATOM   3279 C CB  . SER A 1 425 ? 207.905 258.369 160.955 1.00 72.85  ? 425  SER D CB  1 
ATOM   3280 O OG  . SER A 1 425 ? 209.210 258.917 161.033 1.00 72.85  ? 425  SER D OG  1 
ATOM   3281 N N   . PRO A 1 426 ? 205.811 256.227 162.347 1.00 77.74  ? 426  PRO D N   1 
ATOM   3282 C CA  . PRO A 1 426 ? 204.428 255.726 162.331 1.00 77.74  ? 426  PRO D CA  1 
ATOM   3283 C C   . PRO A 1 426 ? 203.452 256.669 161.654 1.00 77.74  ? 426  PRO D C   1 
ATOM   3284 O O   . PRO A 1 426 ? 202.382 256.220 161.224 1.00 77.74  ? 426  PRO D O   1 
ATOM   3285 C CB  . PRO A 1 426 ? 204.099 255.556 163.820 1.00 77.74  ? 426  PRO D CB  1 
ATOM   3286 C CG  . PRO A 1 426 ? 204.991 256.534 164.509 1.00 77.74  ? 426  PRO D CG  1 
ATOM   3287 C CD  . PRO A 1 426 ? 206.264 256.565 163.708 1.00 77.74  ? 426  PRO D CD  1 
ATOM   3288 N N   . ASP A 1 427 ? 203.780 257.954 161.545 1.00 83.34  ? 427  ASP D N   1 
ATOM   3289 C CA  . ASP A 1 427 ? 202.922 258.916 160.866 1.00 83.34  ? 427  ASP D CA  1 
ATOM   3290 C C   . ASP A 1 427 ? 203.122 258.928 159.357 1.00 83.34  ? 427  ASP D C   1 
ATOM   3291 O O   . ASP A 1 427 ? 202.473 259.724 158.670 1.00 83.34  ? 427  ASP D O   1 
ATOM   3292 C CB  . ASP A 1 427 ? 203.162 260.320 161.428 1.00 83.34  ? 427  ASP D CB  1 
ATOM   3293 C CG  . ASP A 1 427 ? 202.892 260.406 162.917 1.00 83.34  ? 427  ASP D CG  1 
ATOM   3294 O OD1 . ASP A 1 427 ? 202.035 259.644 163.412 1.00 83.34  ? 427  ASP D OD1 1 
ATOM   3295 O OD2 . ASP A 1 427 ? 203.537 261.234 163.593 1.00 83.34  ? 427  ASP D OD2 1 
ATOM   3296 N N   . PHE A 1 428 ? 203.998 258.077 158.829 1.00 76.84  ? 428  PHE D N   1 
ATOM   3297 C CA  . PHE A 1 428 ? 204.250 258.040 157.394 1.00 76.84  ? 428  PHE D CA  1 
ATOM   3298 C C   . PHE A 1 428 ? 203.049 257.440 156.672 1.00 76.84  ? 428  PHE D C   1 
ATOM   3299 O O   . PHE A 1 428 ? 202.619 256.325 156.986 1.00 76.84  ? 428  PHE D O   1 
ATOM   3300 C CB  . PHE A 1 428 ? 205.513 257.235 157.102 1.00 76.84  ? 428  PHE D CB  1 
ATOM   3301 C CG  . PHE A 1 428 ? 205.933 257.266 155.661 1.00 76.84  ? 428  PHE D CG  1 
ATOM   3302 C CD1 . PHE A 1 428 ? 205.586 256.237 154.801 1.00 76.84  ? 428  PHE D CD1 1 
ATOM   3303 C CD2 . PHE A 1 428 ? 206.675 258.324 155.167 1.00 76.84  ? 428  PHE D CD2 1 
ATOM   3304 C CE1 . PHE A 1 428 ? 205.972 256.265 153.475 1.00 76.84  ? 428  PHE D CE1 1 
ATOM   3305 C CE2 . PHE A 1 428 ? 207.064 258.358 153.842 1.00 76.84  ? 428  PHE D CE2 1 
ATOM   3306 C CZ  . PHE A 1 428 ? 206.712 257.327 152.995 1.00 76.84  ? 428  PHE D CZ  1 
ATOM   3307 N N   . GLN A 1 429 ? 202.510 258.177 155.706 1.00 81.45  ? 429  GLN D N   1 
ATOM   3308 C CA  . GLN A 1 429 ? 201.357 257.726 154.944 1.00 81.45  ? 429  GLN D CA  1 
ATOM   3309 C C   . GLN A 1 429 ? 201.804 256.998 153.683 1.00 81.45  ? 429  GLN D C   1 
ATOM   3310 O O   . GLN A 1 429 ? 202.859 257.287 153.112 1.00 81.45  ? 429  GLN D O   1 
ATOM   3311 C CB  . GLN A 1 429 ? 200.450 258.903 154.574 1.00 81.45  ? 429  GLN D CB  1 
ATOM   3312 C CG  . GLN A 1 429 ? 201.067 259.909 153.609 1.00 81.45  ? 429  GLN D CG  1 
ATOM   3313 C CD  . GLN A 1 429 ? 202.070 260.832 154.274 1.00 81.45  ? 429  GLN D CD  1 
ATOM   3314 O OE1 . GLN A 1 429 ? 202.221 260.829 155.496 1.00 81.45  ? 429  GLN D OE1 1 
ATOM   3315 N NE2 . GLN A 1 429 ? 202.764 261.630 153.470 1.00 81.45  ? 429  GLN D NE2 1 
ATOM   3316 N N   . GLU A 1 430 ? 200.987 256.039 153.254 1.00 80.56  ? 430  GLU D N   1 
ATOM   3317 C CA  . GLU A 1 430 ? 201.281 255.231 152.073 1.00 80.56  ? 430  GLU D CA  1 
ATOM   3318 C C   . GLU A 1 430 ? 200.610 255.879 150.868 1.00 80.56  ? 430  GLU D C   1 
ATOM   3319 O O   . GLU A 1 430 ? 199.400 255.749 150.671 1.00 80.56  ? 430  GLU D O   1 
ATOM   3320 C CB  . GLU A 1 430 ? 200.812 253.793 152.267 1.00 80.56  ? 430  GLU D CB  1 
ATOM   3321 C CG  . GLU A 1 430 ? 201.605 253.001 153.300 1.00 80.56  ? 430  GLU D CG  1 
ATOM   3322 C CD  . GLU A 1 430 ? 201.250 253.367 154.729 1.00 80.56  ? 430  GLU D CD  1 
ATOM   3323 O OE1 . GLU A 1 430 ? 200.240 254.074 154.932 1.00 80.56  ? 430  GLU D OE1 1 
ATOM   3324 O OE2 . GLU A 1 430 ? 201.981 252.947 155.650 1.00 80.56  ? 430  GLU D OE2 1 
ATOM   3325 N N   . ASP A 1 431 ? 201.399 256.579 150.061 1.00 74.23  ? 431  ASP D N   1 
ATOM   3326 C CA  . ASP A 1 431 ? 200.903 257.205 148.846 1.00 74.23  ? 431  ASP D CA  1 
ATOM   3327 C C   . ASP A 1 431 ? 201.044 256.242 147.674 1.00 74.23  ? 431  ASP D C   1 
ATOM   3328 O O   . ASP A 1 431 ? 201.968 255.426 147.622 1.00 74.23  ? 431  ASP D O   1 
ATOM   3329 C CB  . ASP A 1 431 ? 201.663 258.501 148.558 1.00 74.23  ? 431  ASP D CB  1 
ATOM   3330 C CG  . ASP A 1 431 ? 200.902 259.433 147.634 1.00 74.23  ? 431  ASP D CG  1 
ATOM   3331 O OD1 . ASP A 1 431 ? 200.007 258.957 146.905 1.00 74.23  ? 431  ASP D OD1 1 
ATOM   3332 O OD2 . ASP A 1 431 ? 201.201 260.646 147.638 1.00 74.23  ? 431  ASP D OD2 1 
ATOM   3333 N N   . ASN A 1 432 ? 200.109 256.343 146.725 1.00 72.60  ? 432  ASN D N   1 
ATOM   3334 C CA  . ASN A 1 432 ? 200.136 255.441 145.580 1.00 72.60  ? 432  ASN D CA  1 
ATOM   3335 C C   . ASN A 1 432 ? 201.269 255.762 144.614 1.00 72.60  ? 432  ASN D C   1 
ATOM   3336 O O   . ASN A 1 432 ? 201.656 254.893 143.827 1.00 72.60  ? 432  ASN D O   1 
ATOM   3337 C CB  . ASN A 1 432 ? 198.792 255.466 144.847 1.00 72.60  ? 432  ASN D CB  1 
ATOM   3338 C CG  . ASN A 1 432 ? 198.339 256.869 144.486 1.00 72.60  ? 432  ASN D CG  1 
ATOM   3339 O OD1 . ASN A 1 432 ? 199.129 257.812 144.476 1.00 72.60  ? 432  ASN D OD1 1 
ATOM   3340 N ND2 . ASN A 1 432 ? 197.054 257.009 144.184 1.00 72.60  ? 432  ASN D ND2 1 
ATOM   3341 N N   . GLU A 1 433 ? 201.817 256.978 144.661 1.00 66.71  ? 433  GLU D N   1 
ATOM   3342 C CA  . GLU A 1 433 ? 202.948 257.310 143.800 1.00 66.71  ? 433  GLU D CA  1 
ATOM   3343 C C   . GLU A 1 433 ? 204.199 256.552 144.227 1.00 66.71  ? 433  GLU D C   1 
ATOM   3344 O O   . GLU A 1 433 ? 204.916 255.990 143.389 1.00 66.71  ? 433  GLU D O   1 
ATOM   3345 C CB  . GLU A 1 433 ? 203.194 258.819 143.815 1.00 66.71  ? 433  GLU D CB  1 
ATOM   3346 C CG  . GLU A 1 433 ? 201.998 259.642 143.365 1.00 66.71  ? 433  GLU D CG  1 
ATOM   3347 C CD  . GLU A 1 433 ? 202.306 261.123 143.282 1.00 66.71  ? 433  GLU D CD  1 
ATOM   3348 O OE1 . GLU A 1 433 ? 203.499 261.488 143.337 1.00 66.71  ? 433  GLU D OE1 1 
ATOM   3349 O OE2 . GLU A 1 433 ? 201.355 261.923 143.162 1.00 66.71  ? 433  GLU D OE2 1 
ATOM   3350 N N   . THR A 1 434 ? 204.480 256.525 145.533 1.00 63.21  ? 434  THR D N   1 
ATOM   3351 C CA  . THR A 1 434 ? 205.592 255.721 146.029 1.00 63.21  ? 434  THR D CA  1 
ATOM   3352 C C   . THR A 1 434 ? 205.360 254.240 145.770 1.00 63.21  ? 434  THR D C   1 
ATOM   3353 O O   . THR A 1 434 ? 206.310 253.502 145.490 1.00 63.21  ? 434  THR D O   1 
ATOM   3354 C CB  . THR A 1 434 ? 205.805 255.970 147.522 1.00 63.21  ? 434  THR D CB  1 
ATOM   3355 O OG1 . THR A 1 434 ? 204.593 255.691 148.234 1.00 63.21  ? 434  THR D OG1 1 
ATOM   3356 C CG2 . THR A 1 434 ? 206.213 257.413 147.769 1.00 63.21  ? 434  THR D CG2 1 
ATOM   3357 N N   . GLU A 1 435 ? 204.105 253.791 145.850 1.00 63.35  ? 435  GLU D N   1 
ATOM   3358 C CA  . GLU A 1 435 ? 203.789 252.404 145.527 1.00 63.35  ? 435  GLU D CA  1 
ATOM   3359 C C   . GLU A 1 435 ? 204.108 252.092 144.070 1.00 63.35  ? 435  GLU D C   1 
ATOM   3360 O O   . GLU A 1 435 ? 204.705 251.053 143.766 1.00 63.35  ? 435  GLU D O   1 
ATOM   3361 C CB  . GLU A 1 435 ? 202.318 252.122 145.829 1.00 63.35  ? 435  GLU D CB  1 
ATOM   3362 C CG  . GLU A 1 435 ? 201.818 250.788 145.310 1.00 63.35  ? 435  GLU D CG  1 
ATOM   3363 C CD  . GLU A 1 435 ? 200.344 250.572 145.593 1.00 63.35  ? 435  GLU D CD  1 
ATOM   3364 O OE1 . GLU A 1 435 ? 199.773 251.342 146.393 1.00 63.35  ? 435  GLU D OE1 1 
ATOM   3365 O OE2 . GLU A 1 435 ? 199.757 249.634 145.014 1.00 63.35  ? 435  GLU D OE2 1 
ATOM   3366 N N   . ILE A 1 436 ? 203.723 252.985 143.156 1.00 59.74  ? 436  ILE D N   1 
ATOM   3367 C CA  . ILE A 1 436 ? 204.007 252.774 141.740 1.00 59.74  ? 436  ILE D CA  1 
ATOM   3368 C C   . ILE A 1 436 ? 205.509 252.798 141.485 1.00 59.74  ? 436  ILE D C   1 
ATOM   3369 O O   . ILE A 1 436 ? 206.028 252.008 140.690 1.00 59.74  ? 436  ILE D O   1 
ATOM   3370 C CB  . ILE A 1 436 ? 203.264 253.817 140.885 1.00 59.74  ? 436  ILE D CB  1 
ATOM   3371 C CG1 . ILE A 1 436 ? 201.756 253.571 140.937 1.00 59.74  ? 436  ILE D CG1 1 
ATOM   3372 C CG2 . ILE A 1 436 ? 203.754 253.786 139.445 1.00 59.74  ? 436  ILE D CG2 1 
ATOM   3373 C CD1 . ILE A 1 436 ? 201.343 252.207 140.431 1.00 59.74  ? 436  ILE D CD1 1 
ATOM   3374 N N   . ASN A 1 437 ? 206.234 253.692 142.163 1.00 57.79  ? 437  ASN D N   1 
ATOM   3375 C CA  . ASN A 1 437 ? 207.684 253.745 141.988 1.00 57.79  ? 437  ASN D CA  1 
ATOM   3376 C C   . ASN A 1 437 ? 208.350 252.465 142.480 1.00 57.79  ? 437  ASN D C   1 
ATOM   3377 O O   . ASN A 1 437 ? 209.244 251.923 141.816 1.00 57.79  ? 437  ASN D O   1 
ATOM   3378 C CB  . ASN A 1 437 ? 208.257 254.962 142.715 1.00 57.79  ? 437  ASN D CB  1 
ATOM   3379 C CG  . ASN A 1 437 ? 207.833 256.272 142.082 1.00 57.79  ? 437  ASN D CG  1 
ATOM   3380 O OD1 . ASN A 1 437 ? 206.885 256.319 141.299 1.00 57.79  ? 437  ASN D OD1 1 
ATOM   3381 N ND2 . ASN A 1 437 ? 208.537 257.346 142.419 1.00 57.79  ? 437  ASN D ND2 1 
ATOM   3382 N N   . PHE A 1 438 ? 207.927 251.966 143.645 1.00 53.96  ? 438  PHE D N   1 
ATOM   3383 C CA  . PHE A 1 438 ? 208.479 250.720 144.164 1.00 53.96  ? 438  PHE D CA  1 
ATOM   3384 C C   . PHE A 1 438 ? 208.154 249.550 143.245 1.00 53.96  ? 438  PHE D C   1 
ATOM   3385 O O   . PHE A 1 438 ? 209.009 248.692 142.993 1.00 53.96  ? 438  PHE D O   1 
ATOM   3386 C CB  . PHE A 1 438 ? 207.949 250.465 145.575 1.00 53.96  ? 438  PHE D CB  1 
ATOM   3387 C CG  . PHE A 1 438 ? 208.395 249.159 146.167 1.00 53.96  ? 438  PHE D CG  1 
ATOM   3388 C CD1 . PHE A 1 438 ? 209.673 249.015 146.678 1.00 53.96  ? 438  PHE D CD1 1 
ATOM   3389 C CD2 . PHE A 1 438 ? 207.531 248.078 146.223 1.00 53.96  ? 438  PHE D CD2 1 
ATOM   3390 C CE1 . PHE A 1 438 ? 210.085 247.816 147.226 1.00 53.96  ? 438  PHE D CE1 1 
ATOM   3391 C CE2 . PHE A 1 438 ? 207.936 246.877 146.771 1.00 53.96  ? 438  PHE D CE2 1 
ATOM   3392 C CZ  . PHE A 1 438 ? 209.214 246.746 147.273 1.00 53.96  ? 438  PHE D CZ  1 
ATOM   3393 N N   . LEU A 1 439 ? 206.923 249.502 142.729 1.00 54.67  ? 439  LEU D N   1 
ATOM   3394 C CA  . LEU A 1 439 ? 206.549 248.430 141.813 1.00 54.67  ? 439  LEU D CA  1 
ATOM   3395 C C   . LEU A 1 439 ? 207.350 248.506 140.521 1.00 54.67  ? 439  LEU D C   1 
ATOM   3396 O O   . LEU A 1 439 ? 207.731 247.474 139.961 1.00 54.67  ? 439  LEU D O   1 
ATOM   3397 C CB  . LEU A 1 439 ? 205.050 248.483 141.521 1.00 54.67  ? 439  LEU D CB  1 
ATOM   3398 C CG  . LEU A 1 439 ? 204.122 248.055 142.659 1.00 54.67  ? 439  LEU D CG  1 
ATOM   3399 C CD1 . LEU A 1 439 ? 202.668 248.131 142.223 1.00 54.67  ? 439  LEU D CD1 1 
ATOM   3400 C CD2 . LEU A 1 439 ? 204.470 246.654 143.135 1.00 54.67  ? 439  LEU D CD2 1 
ATOM   3401 N N   . LEU A 1 440 ? 207.634 249.718 140.040 1.00 53.76  ? 440  LEU D N   1 
ATOM   3402 C CA  . LEU A 1 440 ? 208.420 249.859 138.819 1.00 53.76  ? 440  LEU D CA  1 
ATOM   3403 C C   . LEU A 1 440 ? 209.867 249.439 139.042 1.00 53.76  ? 440  LEU D C   1 
ATOM   3404 O O   . LEU A 1 440 ? 210.477 248.812 138.169 1.00 53.76  ? 440  LEU D O   1 
ATOM   3405 C CB  . LEU A 1 440 ? 208.348 251.298 138.311 1.00 53.76  ? 440  LEU D CB  1 
ATOM   3406 C CG  . LEU A 1 440 ? 209.123 251.589 137.025 1.00 53.76  ? 440  LEU D CG  1 
ATOM   3407 C CD1 . LEU A 1 440 ? 208.229 252.279 136.012 1.00 53.76  ? 440  LEU D CD1 1 
ATOM   3408 C CD2 . LEU A 1 440 ? 210.354 252.431 137.318 1.00 53.76  ? 440  LEU D CD2 1 
ATOM   3409 N N   . LYS A 1 441 ? 210.434 249.776 140.203 1.00 52.89  ? 441  LYS D N   1 
ATOM   3410 C CA  . LYS A 1 441 ? 211.784 249.317 140.519 1.00 52.89  ? 441  LYS D CA  1 
ATOM   3411 C C   . LYS A 1 441 ? 211.834 247.795 140.603 1.00 52.89  ? 441  LYS D C   1 
ATOM   3412 O O   . LYS A 1 441 ? 212.738 247.156 140.044 1.00 52.89  ? 441  LYS D O   1 
ATOM   3413 C CB  . LYS A 1 441 ? 212.261 249.948 141.828 1.00 52.89  ? 441  LYS D CB  1 
ATOM   3414 C CG  . LYS A 1 441 ? 213.613 249.437 142.302 1.00 52.89  ? 441  LYS D CG  1 
ATOM   3415 C CD  . LYS A 1 441 ? 214.016 250.069 143.623 1.00 52.89  ? 441  LYS D CD  1 
ATOM   3416 C CE  . LYS A 1 441 ? 214.237 251.564 143.476 1.00 52.89  ? 441  LYS D CE  1 
ATOM   3417 N NZ  . LYS A 1 441 ? 215.336 251.866 142.519 1.00 52.89  ? 441  LYS D NZ  1 
ATOM   3418 N N   . GLN A 1 442 ? 210.861 247.196 141.296 1.00 51.77  ? 442  GLN D N   1 
ATOM   3419 C CA  . GLN A 1 442 ? 210.800 245.741 141.384 1.00 51.77  ? 442  GLN D CA  1 
ATOM   3420 C C   . GLN A 1 442 ? 210.631 245.113 140.007 1.00 51.77  ? 442  GLN D C   1 
ATOM   3421 O O   . GLN A 1 442 ? 211.223 244.068 139.717 1.00 51.77  ? 442  GLN D O   1 
ATOM   3422 C CB  . GLN A 1 442 ? 209.663 245.315 142.314 1.00 51.77  ? 442  GLN D CB  1 
ATOM   3423 C CG  . GLN A 1 442 ? 209.861 245.709 143.770 1.00 51.77  ? 442  GLN D CG  1 
ATOM   3424 C CD  . GLN A 1 442 ? 210.970 244.926 144.448 1.00 51.77  ? 442  GLN D CD  1 
ATOM   3425 O OE1 . GLN A 1 442 ? 211.582 245.398 145.406 1.00 51.77  ? 442  GLN D OE1 1 
ATOM   3426 N NE2 . GLN A 1 442 ? 211.227 243.718 143.960 1.00 51.77  ? 442  GLN D NE2 1 
ATOM   3427 N N   . ALA A 1 443 ? 209.834 245.740 139.141 1.00 52.31  ? 443  ALA D N   1 
ATOM   3428 C CA  . ALA A 1 443 ? 209.664 245.233 137.785 1.00 52.31  ? 443  ALA D CA  1 
ATOM   3429 C C   . ALA A 1 443 ? 210.981 245.266 137.025 1.00 52.31  ? 443  ALA D C   1 
ATOM   3430 O O   . ALA A 1 443 ? 211.410 244.252 136.469 1.00 52.31  ? 443  ALA D O   1 
ATOM   3431 C CB  . ALA A 1 443 ? 208.597 246.040 137.050 1.00 52.31  ? 443  ALA D CB  1 
ATOM   3432 N N   . LEU A 1 444 ? 211.651 246.421 137.022 1.00 52.86  ? 444  LEU D N   1 
ATOM   3433 C CA  . LEU A 1 444 ? 212.914 246.548 136.304 1.00 52.86  ? 444  LEU D CA  1 
ATOM   3434 C C   . LEU A 1 444 ? 213.967 245.580 136.829 1.00 52.86  ? 444  LEU D C   1 
ATOM   3435 O O   . LEU A 1 444 ? 214.829 245.133 136.064 1.00 52.86  ? 444  LEU D O   1 
ATOM   3436 C CB  . LEU A 1 444 ? 213.428 247.985 136.391 1.00 52.86  ? 444  LEU D CB  1 
ATOM   3437 C CG  . LEU A 1 444 ? 212.603 249.055 135.674 1.00 52.86  ? 444  LEU D CG  1 
ATOM   3438 C CD1 . LEU A 1 444 ? 213.238 250.424 135.846 1.00 52.86  ? 444  LEU D CD1 1 
ATOM   3439 C CD2 . LEU A 1 444 ? 212.447 248.715 134.201 1.00 52.86  ? 444  LEU D CD2 1 
ATOM   3440 N N   . THR A 1 445 ? 213.920 245.239 138.117 1.00 53.71  ? 445  THR D N   1 
ATOM   3441 C CA  . THR A 1 445 ? 214.927 244.341 138.669 1.00 53.71  ? 445  THR D CA  1 
ATOM   3442 C C   . THR A 1 445 ? 214.522 242.870 138.641 1.00 53.71  ? 445  THR D C   1 
ATOM   3443 O O   . THR A 1 445 ? 215.374 242.010 138.888 1.00 53.71  ? 445  THR D O   1 
ATOM   3444 C CB  . THR A 1 445 ? 215.272 244.740 140.110 1.00 53.71  ? 445  THR D CB  1 
ATOM   3445 O OG1 . THR A 1 445 ? 216.465 244.062 140.520 1.00 53.71  ? 445  THR D OG1 1 
ATOM   3446 C CG2 . THR A 1 445 ? 214.146 244.363 141.053 1.00 53.71  ? 445  THR D CG2 1 
ATOM   3447 N N   . ILE A 1 446 ? 213.259 242.553 138.350 1.00 52.37  ? 446  ILE D N   1 
ATOM   3448 C CA  . ILE A 1 446 ? 212.808 241.165 138.383 1.00 52.37  ? 446  ILE D CA  1 
ATOM   3449 C C   . ILE A 1 446 ? 212.315 240.710 137.014 1.00 52.37  ? 446  ILE D C   1 
ATOM   3450 O O   . ILE A 1 446 ? 212.831 239.741 136.448 1.00 52.37  ? 446  ILE D O   1 
ATOM   3451 C CB  . ILE A 1 446 ? 211.711 240.979 139.447 1.00 52.37  ? 446  ILE D CB  1 
ATOM   3452 C CG1 . ILE A 1 446 ? 212.293 241.169 140.849 1.00 52.37  ? 446  ILE D CG1 1 
ATOM   3453 C CG2 . ILE A 1 446 ? 211.064 239.614 139.315 1.00 52.37  ? 446  ILE D CG2 1 
ATOM   3454 C CD1 . ILE A 1 446 ? 211.281 241.000 141.958 1.00 52.37  ? 446  ILE D CD1 1 
ATOM   3455 N N   . VAL A 1 447 ? 211.304 241.396 136.478 1.00 52.86  ? 447  VAL D N   1 
ATOM   3456 C CA  . VAL A 1 447 ? 210.712 240.979 135.213 1.00 52.86  ? 447  VAL D CA  1 
ATOM   3457 C C   . VAL A 1 447 ? 211.580 241.368 134.025 1.00 52.86  ? 447  VAL D C   1 
ATOM   3458 O O   . VAL A 1 447 ? 211.424 240.797 132.939 1.00 52.86  ? 447  VAL D O   1 
ATOM   3459 C CB  . VAL A 1 447 ? 209.301 241.576 135.062 1.00 52.86  ? 447  VAL D CB  1 
ATOM   3460 C CG1 . VAL A 1 447 ? 208.503 240.822 134.007 1.00 52.86  ? 447  VAL D CG1 1 
ATOM   3461 C CG2 . VAL A 1 447 ? 208.575 241.562 136.398 1.00 52.86  ? 447  VAL D CG2 1 
ATOM   3462 N N   . GLY A 1 448 ? 212.499 242.320 134.200 1.00 53.46  ? 448  GLY D N   1 
ATOM   3463 C CA  . GLY A 1 448 ? 213.359 242.716 133.100 1.00 53.46  ? 448  GLY D CA  1 
ATOM   3464 C C   . GLY A 1 448 ? 214.341 241.639 132.688 1.00 53.46  ? 448  GLY D C   1 
ATOM   3465 O O   . GLY A 1 448 ? 214.748 241.580 131.524 1.00 53.46  ? 448  GLY D O   1 
ATOM   3466 N N   . THR A 1 449 ? 214.732 240.776 133.622 1.00 54.80  ? 449  THR D N   1 
ATOM   3467 C CA  . THR A 1 449 ? 215.677 239.706 133.338 1.00 54.80  ? 449  THR D CA  1 
ATOM   3468 C C   . THR A 1 449 ? 214.999 238.394 132.964 1.00 54.80  ? 449  THR D C   1 
ATOM   3469 O O   . THR A 1 449 ? 215.696 237.426 132.647 1.00 54.80  ? 449  THR D O   1 
ATOM   3470 C CB  . THR A 1 449 ? 216.601 239.476 134.539 1.00 54.80  ? 449  THR D CB  1 
ATOM   3471 O OG1 . THR A 1 449 ? 217.621 238.534 134.186 1.00 54.80  ? 449  THR D OG1 1 
ATOM   3472 C CG2 . THR A 1 449 ? 215.816 238.934 135.721 1.00 54.80  ? 449  THR D CG2 1 
ATOM   3473 N N   . LEU A 1 450 ? 213.664 238.336 132.990 1.00 55.23  ? 450  LEU D N   1 
ATOM   3474 C CA  . LEU A 1 450 ? 212.989 237.086 132.639 1.00 55.23  ? 450  LEU D CA  1 
ATOM   3475 C C   . LEU A 1 450 ? 213.042 236.803 131.143 1.00 55.23  ? 450  LEU D C   1 
ATOM   3476 O O   . LEU A 1 450 ? 213.396 235.671 130.766 1.00 55.23  ? 450  LEU D O   1 
ATOM   3477 C CB  . LEU A 1 450 ? 211.554 237.097 133.175 1.00 55.23  ? 450  LEU D CB  1 
ATOM   3478 C CG  . LEU A 1 450 ? 211.431 237.019 134.696 1.00 55.23  ? 450  LEU D CG  1 
ATOM   3479 C CD1 . LEU A 1 450 ? 209.977 236.896 135.116 1.00 55.23  ? 450  LEU D CD1 1 
ATOM   3480 C CD2 . LEU A 1 450 ? 212.249 235.854 135.226 1.00 55.23  ? 450  LEU D CD2 1 
ATOM   3481 N N   . PRO A 1 451 ? 212.710 237.741 130.244 1.00 55.66  ? 451  PRO D N   1 
ATOM   3482 C CA  . PRO A 1 451 ? 212.903 237.446 128.815 1.00 55.66  ? 451  PRO D CA  1 
ATOM   3483 C C   . PRO A 1 451 ? 214.358 237.231 128.448 1.00 55.66  ? 451  PRO D C   1 
ATOM   3484 O O   . PRO A 1 451 ? 214.657 236.394 127.590 1.00 55.66  ? 451  PRO D O   1 
ATOM   3485 C CB  . PRO A 1 451 ? 212.314 238.682 128.119 1.00 55.66  ? 451  PRO D CB  1 
ATOM   3486 C CG  . PRO A 1 451 ? 211.378 239.261 129.109 1.00 55.66  ? 451  PRO D CG  1 
ATOM   3487 C CD  . PRO A 1 451 ? 212.034 239.036 130.432 1.00 55.66  ? 451  PRO D CD  1 
ATOM   3488 N N   . PHE A 1 452 ? 215.276 237.961 129.084 1.00 55.98  ? 452  PHE D N   1 
ATOM   3489 C CA  . PHE A 1 452 ? 216.698 237.761 128.822 1.00 55.98  ? 452  PHE D CA  1 
ATOM   3490 C C   . PHE A 1 452 ? 217.135 236.358 129.227 1.00 55.98  ? 452  PHE D C   1 
ATOM   3491 O O   . PHE A 1 452 ? 217.818 235.662 128.465 1.00 55.98  ? 452  PHE D O   1 
ATOM   3492 C CB  . PHE A 1 452 ? 217.517 238.820 129.562 1.00 55.98  ? 452  PHE D CB  1 
ATOM   3493 C CG  . PHE A 1 452 ? 219.002 238.660 129.406 1.00 55.98  ? 452  PHE D CG  1 
ATOM   3494 C CD1 . PHE A 1 452 ? 219.754 238.042 130.391 1.00 55.98  ? 452  PHE D CD1 1 
ATOM   3495 C CD2 . PHE A 1 452 ? 219.646 239.130 128.274 1.00 55.98  ? 452  PHE D CD2 1 
ATOM   3496 C CE1 . PHE A 1 452 ? 221.120 237.895 130.249 1.00 55.98  ? 452  PHE D CE1 1 
ATOM   3497 C CE2 . PHE A 1 452 ? 221.011 238.986 128.127 1.00 55.98  ? 452  PHE D CE2 1 
ATOM   3498 C CZ  . PHE A 1 452 ? 221.749 238.368 129.115 1.00 55.98  ? 452  PHE D CZ  1 
ATOM   3499 N N   . THR A 1 453 ? 216.749 235.929 130.432 1.00 54.26  ? 453  THR D N   1 
ATOM   3500 C CA  . THR A 1 453 ? 217.074 234.580 130.884 1.00 54.26  ? 453  THR D CA  1 
ATOM   3501 C C   . THR A 1 453 ? 216.462 233.531 129.967 1.00 54.26  ? 453  THR D C   1 
ATOM   3502 O O   . THR A 1 453 ? 217.127 232.557 129.593 1.00 54.26  ? 453  THR D O   1 
ATOM   3503 C CB  . THR A 1 453 ? 216.591 234.379 132.322 1.00 54.26  ? 453  THR D CB  1 
ATOM   3504 O OG1 . THR A 1 453 ? 217.356 235.207 133.208 1.00 54.26  ? 453  THR D OG1 1 
ATOM   3505 C CG2 . THR A 1 453 ? 216.730 232.924 132.741 1.00 54.26  ? 453  THR D CG2 1 
ATOM   3506 N N   . TYR A 1 454 ? 215.194 233.716 129.592 1.00 55.55  ? 454  TYR D N   1 
ATOM   3507 C CA  . TYR A 1 454 ? 214.526 232.759 128.717 1.00 55.55  ? 454  TYR D CA  1 
ATOM   3508 C C   . TYR A 1 454 ? 215.237 232.652 127.374 1.00 55.55  ? 454  TYR D C   1 
ATOM   3509 O O   . TYR A 1 454 ? 215.495 231.548 126.884 1.00 55.55  ? 454  TYR D O   1 
ATOM   3510 C CB  . TYR A 1 454 ? 213.063 233.162 128.525 1.00 55.55  ? 454  TYR D CB  1 
ATOM   3511 C CG  . TYR A 1 454 ? 212.358 232.415 127.417 1.00 55.55  ? 454  TYR D CG  1 
ATOM   3512 C CD1 . TYR A 1 454 ? 211.975 231.092 127.578 1.00 55.55  ? 454  TYR D CD1 1 
ATOM   3513 C CD2 . TYR A 1 454 ? 212.066 233.038 126.210 1.00 55.55  ? 454  TYR D CD2 1 
ATOM   3514 C CE1 . TYR A 1 454 ? 211.329 230.406 126.568 1.00 55.55  ? 454  TYR D CE1 1 
ATOM   3515 C CE2 . TYR A 1 454 ? 211.420 232.361 125.195 1.00 55.55  ? 454  TYR D CE2 1 
ATOM   3516 C CZ  . TYR A 1 454 ? 211.053 231.046 125.379 1.00 55.55  ? 454  TYR D CZ  1 
ATOM   3517 O OH  . TYR A 1 454 ? 210.409 230.368 124.370 1.00 55.55  ? 454  TYR D OH  1 
ATOM   3518 N N   . MET A 1 455 ? 215.571 233.794 126.769 1.00 59.48  ? 455  MET D N   1 
ATOM   3519 C CA  . MET A 1 455 ? 216.226 233.781 125.466 1.00 59.48  ? 455  MET D CA  1 
ATOM   3520 C C   . MET A 1 455 ? 217.612 233.156 125.550 1.00 59.48  ? 455  MET D C   1 
ATOM   3521 O O   . MET A 1 455 ? 217.985 232.350 124.690 1.00 59.48  ? 455  MET D O   1 
ATOM   3522 C CB  . MET A 1 455 ? 216.301 235.204 124.909 1.00 59.48  ? 455  MET D CB  1 
ATOM   3523 C CG  . MET A 1 455 ? 216.756 235.297 123.459 1.00 59.48  ? 455  MET D CG  1 
ATOM   3524 S SD  . MET A 1 455 ? 218.546 235.389 123.274 1.00 59.48  ? 455  MET D SD  1 
ATOM   3525 C CE  . MET A 1 455 ? 218.909 236.821 124.285 1.00 59.48  ? 455  MET D CE  1 
ATOM   3526 N N   . LEU A 1 456 ? 218.386 233.501 126.583 1.00 56.99  ? 456  LEU D N   1 
ATOM   3527 C CA  . LEU A 1 456 ? 219.722 232.932 126.725 1.00 56.99  ? 456  LEU D CA  1 
ATOM   3528 C C   . LEU A 1 456 ? 219.658 231.423 126.920 1.00 56.99  ? 456  LEU D C   1 
ATOM   3529 O O   . LEU A 1 456 ? 220.402 230.669 126.280 1.00 56.99  ? 456  LEU D O   1 
ATOM   3530 C CB  . LEU A 1 456 ? 220.452 233.597 127.893 1.00 56.99  ? 456  LEU D CB  1 
ATOM   3531 C CG  . LEU A 1 456 ? 221.819 233.012 128.257 1.00 56.99  ? 456  LEU D CG  1 
ATOM   3532 C CD1 . LEU A 1 456 ? 222.782 233.115 127.086 1.00 56.99  ? 456  LEU D CD1 1 
ATOM   3533 C CD2 . LEU A 1 456 ? 222.388 233.703 129.483 1.00 56.99  ? 456  LEU D CD2 1 
ATOM   3534 N N   . GLU A 1 457 ? 218.763 230.960 127.796 1.00 58.09  ? 457  GLU D N   1 
ATOM   3535 C CA  . GLU A 1 457 ? 218.672 229.530 128.064 1.00 58.09  ? 457  GLU D CA  1 
ATOM   3536 C C   . GLU A 1 457 ? 218.152 228.771 126.850 1.00 58.09  ? 457  GLU D C   1 
ATOM   3537 O O   . GLU A 1 457 ? 218.611 227.659 126.567 1.00 58.09  ? 457  GLU D O   1 
ATOM   3538 C CB  . GLU A 1 457 ? 217.785 229.280 129.282 1.00 58.09  ? 457  GLU D CB  1 
ATOM   3539 C CG  . GLU A 1 457 ? 217.818 227.848 129.784 1.00 58.09  ? 457  GLU D CG  1 
ATOM   3540 C CD  . GLU A 1 457 ? 219.187 227.432 130.293 1.00 58.09  ? 457  GLU D CD  1 
ATOM   3541 O OE1 . GLU A 1 457 ? 219.968 228.314 130.706 1.00 58.09  ? 457  GLU D OE1 1 
ATOM   3542 O OE2 . GLU A 1 457 ? 219.482 226.219 130.279 1.00 58.09  ? 457  GLU D OE2 1 
ATOM   3543 N N   . LYS A 1 458 ? 217.210 229.358 126.108 1.00 57.60  ? 458  LYS D N   1 
ATOM   3544 C CA  . LYS A 1 458 ? 216.714 228.706 124.902 1.00 57.60  ? 458  LYS D CA  1 
ATOM   3545 C C   . LYS A 1 458 ? 217.794 228.637 123.831 1.00 57.60  ? 458  LYS D C   1 
ATOM   3546 O O   . LYS A 1 458 ? 217.913 227.629 123.125 1.00 57.60  ? 458  LYS D O   1 
ATOM   3547 C CB  . LYS A 1 458 ? 215.479 229.441 124.381 1.00 57.60  ? 458  LYS D CB  1 
ATOM   3548 C CG  . LYS A 1 458 ? 214.767 228.737 123.239 1.00 57.60  ? 458  LYS D CG  1 
ATOM   3549 C CD  . LYS A 1 458 ? 213.504 229.482 122.839 1.00 57.60  ? 458  LYS D CD  1 
ATOM   3550 C CE  . LYS A 1 458 ? 212.759 228.753 121.734 1.00 57.60  ? 458  LYS D CE  1 
ATOM   3551 N NZ  . LYS A 1 458 ? 212.341 227.388 122.155 1.00 57.60  ? 458  LYS D NZ  1 
ATOM   3552 N N   . TRP A 1 459 ? 218.599 229.696 123.701 1.00 59.69  ? 459  TRP D N   1 
ATOM   3553 C CA  . TRP A 1 459 ? 219.704 229.670 122.750 1.00 59.69  ? 459  TRP D CA  1 
ATOM   3554 C C   . TRP A 1 459 ? 220.725 228.604 123.126 1.00 59.69  ? 459  TRP D C   1 
ATOM   3555 O O   . TRP A 1 459 ? 221.217 227.874 122.258 1.00 59.69  ? 459  TRP D O   1 
ATOM   3556 C CB  . TRP A 1 459 ? 220.363 231.047 122.674 1.00 59.69  ? 459  TRP D CB  1 
ATOM   3557 C CG  . TRP A 1 459 ? 221.472 231.128 121.672 1.00 59.69  ? 459  TRP D CG  1 
ATOM   3558 C CD1 . TRP A 1 459 ? 221.351 231.358 120.333 1.00 59.69  ? 459  TRP D CD1 1 
ATOM   3559 C CD2 . TRP A 1 459 ? 222.874 230.983 121.929 1.00 59.69  ? 459  TRP D CD2 1 
ATOM   3560 N NE1 . TRP A 1 459 ? 222.590 231.363 119.739 1.00 59.69  ? 459  TRP D NE1 1 
ATOM   3561 C CE2 . TRP A 1 459 ? 223.542 231.136 120.698 1.00 59.69  ? 459  TRP D CE2 1 
ATOM   3562 C CE3 . TRP A 1 459 ? 223.629 230.738 123.080 1.00 59.69  ? 459  TRP D CE3 1 
ATOM   3563 C CZ2 . TRP A 1 459 ? 224.928 231.052 120.585 1.00 59.69  ? 459  TRP D CZ2 1 
ATOM   3564 C CZ3 . TRP A 1 459 ? 225.005 230.655 122.965 1.00 59.69  ? 459  TRP D CZ3 1 
ATOM   3565 C CH2 . TRP A 1 459 ? 225.639 230.812 121.727 1.00 59.69  ? 459  TRP D CH2 1 
ATOM   3566 N N   . ARG A 1 460 ? 221.048 228.492 124.417 1.00 58.35  ? 460  ARG D N   1 
ATOM   3567 C CA  . ARG A 1 460 ? 221.988 227.459 124.847 1.00 58.35  ? 460  ARG D CA  1 
ATOM   3568 C C   . ARG A 1 460 ? 221.418 226.063 124.621 1.00 58.35  ? 460  ARG D C   1 
ATOM   3569 O O   . ARG A 1 460 ? 222.140 225.153 124.198 1.00 58.35  ? 460  ARG D O   1 
ATOM   3570 C CB  . ARG A 1 460 ? 222.360 227.659 126.316 1.00 58.35  ? 460  ARG D CB  1 
ATOM   3571 C CG  . ARG A 1 460 ? 223.022 228.994 126.607 1.00 58.35  ? 460  ARG D CG  1 
ATOM   3572 C CD  . ARG A 1 460 ? 223.460 229.097 128.057 1.00 58.35  ? 460  ARG D CD  1 
ATOM   3573 N NE  . ARG A 1 460 ? 224.791 228.537 128.266 1.00 58.35  ? 460  ARG D NE  1 
ATOM   3574 C CZ  . ARG A 1 460 ? 225.424 228.535 129.434 1.00 58.35  ? 460  ARG D CZ  1 
ATOM   3575 N NH1 . ARG A 1 460 ? 226.637 228.008 129.532 1.00 58.35  ? 460  ARG D NH1 1 
ATOM   3576 N NH2 . ARG A 1 460 ? 224.845 229.060 130.505 1.00 58.35  ? 460  ARG D NH2 1 
ATOM   3577 N N   . TRP A 1 461 ? 220.121 225.879 124.878 1.00 56.76  ? 461  TRP D N   1 
ATOM   3578 C CA  . TRP A 1 461 ? 219.499 224.580 124.651 1.00 56.76  ? 461  TRP D CA  1 
ATOM   3579 C C   . TRP A 1 461 ? 219.516 224.207 123.174 1.00 56.76  ? 461  TRP D C   1 
ATOM   3580 O O   . TRP A 1 461 ? 219.814 223.060 122.820 1.00 56.76  ? 461  TRP D O   1 
ATOM   3581 C CB  . TRP A 1 461 ? 218.068 224.585 125.188 1.00 56.76  ? 461  TRP D CB  1 
ATOM   3582 C CG  . TRP A 1 461 ? 217.983 224.467 126.678 1.00 56.76  ? 461  TRP D CG  1 
ATOM   3583 C CD1 . TRP A 1 461 ? 218.963 224.032 127.522 1.00 56.76  ? 461  TRP D CD1 1 
ATOM   3584 C CD2 . TRP A 1 461 ? 216.857 224.789 127.502 1.00 56.76  ? 461  TRP D CD2 1 
ATOM   3585 N NE1 . TRP A 1 461 ? 218.516 224.061 128.821 1.00 56.76  ? 461  TRP D NE1 1 
ATOM   3586 C CE2 . TRP A 1 461 ? 217.226 224.522 128.835 1.00 56.76  ? 461  TRP D CE2 1 
ATOM   3587 C CE3 . TRP A 1 461 ? 215.573 225.277 127.242 1.00 56.76  ? 461  TRP D CE3 1 
ATOM   3588 C CZ2 . TRP A 1 461 ? 216.357 224.725 129.905 1.00 56.76  ? 461  TRP D CZ2 1 
ATOM   3589 C CZ3 . TRP A 1 461 ? 214.713 225.479 128.306 1.00 56.76  ? 461  TRP D CZ3 1 
ATOM   3590 C CH2 . TRP A 1 461 ? 215.108 225.204 129.620 1.00 56.76  ? 461  TRP D CH2 1 
ATOM   3591 N N   . MET A 1 462 ? 219.207 225.164 122.295 1.00 59.85  ? 462  MET D N   1 
ATOM   3592 C CA  . MET A 1 462 ? 219.188 224.872 120.868 1.00 59.85  ? 462  MET D CA  1 
ATOM   3593 C C   . MET A 1 462 ? 220.588 224.735 120.282 1.00 59.85  ? 462  MET D C   1 
ATOM   3594 O O   . MET A 1 462 ? 220.749 224.071 119.253 1.00 59.85  ? 462  MET D O   1 
ATOM   3595 C CB  . MET A 1 462 ? 218.409 225.951 120.115 1.00 59.85  ? 462  MET D CB  1 
ATOM   3596 C CG  . MET A 1 462 ? 216.936 226.016 120.485 1.00 59.85  ? 462  MET D CG  1 
ATOM   3597 S SD  . MET A 1 462 ? 215.935 226.859 119.246 1.00 59.85  ? 462  MET D SD  1 
ATOM   3598 C CE  . MET A 1 462 ? 216.838 228.393 119.073 1.00 59.85  ? 462  MET D CE  1 
ATOM   3599 N N   . VAL A 1 463 ? 221.600 225.342 120.905 1.00 58.89  ? 463  VAL D N   1 
ATOM   3600 C CA  . VAL A 1 463 ? 222.965 225.151 120.428 1.00 58.89  ? 463  VAL D CA  1 
ATOM   3601 C C   . VAL A 1 463 ? 223.580 223.870 120.979 1.00 58.89  ? 463  VAL D C   1 
ATOM   3602 O O   . VAL A 1 463 ? 224.515 223.331 120.374 1.00 58.89  ? 463  VAL D O   1 
ATOM   3603 C CB  . VAL A 1 463 ? 223.842 226.369 120.773 1.00 58.89  ? 463  VAL D CB  1 
ATOM   3604 C CG1 . VAL A 1 463 ? 224.293 226.330 122.223 1.00 58.89  ? 463  VAL D CG1 1 
ATOM   3605 C CG2 . VAL A 1 463 ? 225.037 226.444 119.842 1.00 58.89  ? 463  VAL D CG2 1 
ATOM   3606 N N   . PHE A 1 464 ? 223.074 223.358 122.104 1.00 58.82  ? 464  PHE D N   1 
ATOM   3607 C CA  . PHE A 1 464 ? 223.539 222.068 122.600 1.00 58.82  ? 464  PHE D CA  1 
ATOM   3608 C C   . PHE A 1 464 ? 222.834 220.914 121.897 1.00 58.82  ? 464  PHE D C   1 
ATOM   3609 O O   . PHE A 1 464 ? 223.453 219.879 121.626 1.00 58.82  ? 464  PHE D O   1 
ATOM   3610 C CB  . PHE A 1 464 ? 223.327 221.975 124.112 1.00 58.82  ? 464  PHE D CB  1 
ATOM   3611 C CG  . PHE A 1 464 ? 224.264 222.834 124.910 1.00 58.82  ? 464  PHE D CG  1 
ATOM   3612 C CD1 . PHE A 1 464 ? 225.521 223.151 124.422 1.00 58.82  ? 464  PHE D CD1 1 
ATOM   3613 C CD2 . PHE A 1 464 ? 223.890 223.324 126.149 1.00 58.82  ? 464  PHE D CD2 1 
ATOM   3614 C CE1 . PHE A 1 464 ? 226.385 223.940 125.155 1.00 58.82  ? 464  PHE D CE1 1 
ATOM   3615 C CE2 . PHE A 1 464 ? 224.750 224.113 126.887 1.00 58.82  ? 464  PHE D CE2 1 
ATOM   3616 C CZ  . PHE A 1 464 ? 225.999 224.422 126.389 1.00 58.82  ? 464  PHE D CZ  1 
ATOM   3617 N N   . LYS A 1 465 ? 221.543 221.074 121.594 1.00 61.32  ? 465  LYS D N   1 
ATOM   3618 C CA  . LYS A 1 465 ? 220.806 220.012 120.920 1.00 61.32  ? 465  LYS D CA  1 
ATOM   3619 C C   . LYS A 1 465 ? 221.243 219.857 119.469 1.00 61.32  ? 465  LYS D C   1 
ATOM   3620 O O   . LYS A 1 465 ? 221.222 218.744 118.931 1.00 61.32  ? 465  LYS D O   1 
ATOM   3621 C CB  . LYS A 1 465 ? 219.304 220.288 120.998 1.00 61.32  ? 465  LYS D CB  1 
ATOM   3622 C CG  . LYS A 1 465 ? 218.432 219.190 120.413 1.00 61.32  ? 465  LYS D CG  1 
ATOM   3623 C CD  . LYS A 1 465 ? 216.958 219.537 120.529 1.00 61.32  ? 465  LYS D CD  1 
ATOM   3624 C CE  . LYS A 1 465 ? 216.551 219.740 121.979 1.00 61.32  ? 465  LYS D CE  1 
ATOM   3625 N NZ  . LYS A 1 465 ? 215.108 220.081 122.108 1.00 61.32  ? 465  LYS D NZ  1 
ATOM   3626 N N   . GLY A 1 466 ? 221.648 220.949 118.826 1.00 60.74  ? 466  GLY D N   1 
ATOM   3627 C CA  . GLY A 1 466 ? 222.076 220.917 117.445 1.00 60.74  ? 466  GLY D CA  1 
ATOM   3628 C C   . GLY A 1 466 ? 221.112 221.524 116.450 1.00 60.74  ? 466  GLY D C   1 
ATOM   3629 O O   . GLY A 1 466 ? 221.274 221.299 115.245 1.00 60.74  ? 466  GLY D O   1 
ATOM   3630 N N   . GLU A 1 467 ? 220.115 222.282 116.907 1.00 64.74  ? 467  GLU D N   1 
ATOM   3631 C CA  . GLU A 1 467 ? 219.160 222.912 116.006 1.00 64.74  ? 467  GLU D CA  1 
ATOM   3632 C C   . GLU A 1 467 ? 219.723 224.144 115.312 1.00 64.74  ? 467  GLU D C   1 
ATOM   3633 O O   . GLU A 1 467 ? 219.124 224.612 114.337 1.00 64.74  ? 467  GLU D O   1 
ATOM   3634 C CB  . GLU A 1 467 ? 217.889 223.291 116.769 1.00 64.74  ? 467  GLU D CB  1 
ATOM   3635 C CG  . GLU A 1 467 ? 217.177 222.114 117.413 1.00 64.74  ? 467  GLU D CG  1 
ATOM   3636 C CD  . GLU A 1 467 ? 215.922 222.529 118.153 1.00 64.74  ? 467  GLU D CD  1 
ATOM   3637 O OE1 . GLU A 1 467 ? 215.639 223.743 118.211 1.00 64.74  ? 467  GLU D OE1 1 
ATOM   3638 O OE2 . GLU A 1 467 ? 215.218 221.640 118.676 1.00 64.74  ? 467  GLU D OE2 1 
ATOM   3639 N N   . ILE A 1 468 ? 220.844 224.677 115.783 1.00 63.71  ? 468  ILE D N   1 
ATOM   3640 C CA  . ILE A 1 468 ? 221.471 225.858 115.206 1.00 63.71  ? 468  ILE D CA  1 
ATOM   3641 C C   . ILE A 1 468 ? 222.822 225.441 114.634 1.00 63.71  ? 468  ILE D C   1 
ATOM   3642 O O   . ILE A 1 468 ? 223.689 224.975 115.379 1.00 63.71  ? 468  ILE D O   1 
ATOM   3643 C CB  . ILE A 1 468 ? 221.647 226.984 116.238 1.00 63.71  ? 468  ILE D CB  1 
ATOM   3644 C CG1 . ILE A 1 468 ? 220.312 227.309 116.909 1.00 63.71  ? 468  ILE D CG1 1 
ATOM   3645 C CG2 . ILE A 1 468 ? 222.229 228.224 115.578 1.00 63.71  ? 468  ILE D CG2 1 
ATOM   3646 C CD1 . ILE A 1 468 ? 220.411 228.385 117.967 1.00 63.71  ? 468  ILE D CD1 1 
ATOM   3647 N N   . PRO A 1 469 ? 223.048 225.577 113.330 1.00 66.07  ? 469  PRO D N   1 
ATOM   3648 C CA  . PRO A 1 469 ? 224.374 225.285 112.778 1.00 66.07  ? 469  PRO D CA  1 
ATOM   3649 C C   . PRO A 1 469 ? 225.414 226.265 113.298 1.00 66.07  ? 469  PRO D C   1 
ATOM   3650 O O   . PRO A 1 469 ? 225.102 227.370 113.748 1.00 66.07  ? 469  PRO D O   1 
ATOM   3651 C CB  . PRO A 1 469 ? 224.174 225.438 111.265 1.00 66.07  ? 469  PRO D CB  1 
ATOM   3652 C CG  . PRO A 1 469 ? 222.698 225.303 111.055 1.00 66.07  ? 469  PRO D CG  1 
ATOM   3653 C CD  . PRO A 1 469 ? 222.067 225.889 112.279 1.00 66.07  ? 469  PRO D CD  1 
ATOM   3654 N N   . LYS A 1 470 ? 226.677 225.839 113.223 1.00 66.86  ? 470  LYS D N   1 
ATOM   3655 C CA  . LYS A 1 470 ? 227.767 226.634 113.779 1.00 66.86  ? 470  LYS D CA  1 
ATOM   3656 C C   . LYS A 1 470 ? 227.949 227.966 113.063 1.00 66.86  ? 470  LYS D C   1 
ATOM   3657 O O   . LYS A 1 470 ? 228.480 228.908 113.660 1.00 66.86  ? 470  LYS D O   1 
ATOM   3658 C CB  . LYS A 1 470 ? 229.073 225.839 113.736 1.00 66.86  ? 470  LYS D CB  1 
ATOM   3659 C CG  . LYS A 1 470 ? 229.065 224.588 114.600 1.00 66.86  ? 470  LYS D CG  1 
ATOM   3660 C CD  . LYS A 1 470 ? 230.416 223.893 114.579 1.00 66.86  ? 470  LYS D CD  1 
ATOM   3661 C CE  . LYS A 1 470 ? 230.804 223.482 113.169 1.00 66.86  ? 470  LYS D CE  1 
ATOM   3662 N NZ  . LYS A 1 470 ? 229.815 222.543 112.573 1.00 66.86  ? 470  LYS D NZ  1 
ATOM   3663 N N   . ASP A 1 471 ? 227.523 228.071 111.804 1.00 71.91  ? 471  ASP D N   1 
ATOM   3664 C CA  . ASP A 1 471 ? 227.652 229.304 111.041 1.00 71.91  ? 471  ASP D CA  1 
ATOM   3665 C C   . ASP A 1 471 ? 226.436 230.215 111.184 1.00 71.91  ? 471  ASP D C   1 
ATOM   3666 O O   . ASP A 1 471 ? 226.274 231.146 110.388 1.00 71.91  ? 471  ASP D O   1 
ATOM   3667 C CB  . ASP A 1 471 ? 227.904 228.988 109.565 1.00 71.91  ? 471  ASP D CB  1 
ATOM   3668 C CG  . ASP A 1 471 ? 226.840 228.087 108.969 1.00 71.91  ? 471  ASP D CG  1 
ATOM   3669 O OD1 . ASP A 1 471 ? 225.960 227.621 109.721 1.00 71.91  ? 471  ASP D OD1 1 
ATOM   3670 O OD2 . ASP A 1 471 ? 226.884 227.846 107.744 1.00 71.91  ? 471  ASP D OD2 1 
ATOM   3671 N N   . GLN A 1 472 ? 225.577 229.963 112.178 1.00 67.82  ? 472  GLN D N   1 
ATOM   3672 C CA  . GLN A 1 472 ? 224.403 230.800 112.397 1.00 67.82  ? 472  GLN D CA  1 
ATOM   3673 C C   . GLN A 1 472 ? 224.180 231.104 113.876 1.00 67.82  ? 472  GLN D C   1 
ATOM   3674 O O   . GLN A 1 472 ? 223.088 231.557 114.245 1.00 67.82  ? 472  GLN D O   1 
ATOM   3675 C CB  . GLN A 1 472 ? 223.144 230.143 111.818 1.00 67.82  ? 472  GLN D CB  1 
ATOM   3676 C CG  . GLN A 1 472 ? 223.155 229.981 110.307 1.00 67.82  ? 472  GLN D CG  1 
ATOM   3677 C CD  . GLN A 1 472 ? 221.887 229.340 109.783 1.00 67.82  ? 472  GLN D CD  1 
ATOM   3678 O OE1 . GLN A 1 472 ? 220.974 229.027 110.546 1.00 67.82  ? 472  GLN D OE1 1 
ATOM   3679 N NE2 . GLN A 1 472 ? 221.824 229.139 108.471 1.00 67.82  ? 472  GLN D NE2 1 
ATOM   3680 N N   . TRP A 1 473 ? 225.187 230.873 114.723 1.00 66.34  ? 473  TRP D N   1 
ATOM   3681 C CA  . TRP A 1 473 ? 225.020 231.050 116.163 1.00 66.34  ? 473  TRP D CA  1 
ATOM   3682 C C   . TRP A 1 473 ? 224.565 232.464 116.500 1.00 66.34  ? 473  TRP D C   1 
ATOM   3683 O O   . TRP A 1 473 ? 223.455 232.670 117.001 1.00 66.34  ? 473  TRP D O   1 
ATOM   3684 C CB  . TRP A 1 473 ? 226.327 230.723 116.889 1.00 66.34  ? 473  TRP D CB  1 
ATOM   3685 C CG  . TRP A 1 473 ? 226.597 229.262 117.041 1.00 66.34  ? 473  TRP D CG  1 
ATOM   3686 C CD1 . TRP A 1 473 ? 225.891 228.235 116.489 1.00 66.34  ? 473  TRP D CD1 1 
ATOM   3687 C CD2 . TRP A 1 473 ? 227.646 228.660 117.808 1.00 66.34  ? 473  TRP D CD2 1 
ATOM   3688 N NE1 . TRP A 1 473 ? 226.439 227.031 116.858 1.00 66.34  ? 473  TRP D NE1 1 
ATOM   3689 C CE2 . TRP A 1 473 ? 227.519 227.265 117.668 1.00 66.34  ? 473  TRP D CE2 1 
ATOM   3690 C CE3 . TRP A 1 473 ? 228.683 229.167 118.597 1.00 66.34  ? 473  TRP D CE3 1 
ATOM   3691 C CZ2 . TRP A 1 473 ? 228.387 226.370 118.289 1.00 66.34  ? 473  TRP D CZ2 1 
ATOM   3692 C CZ3 . TRP A 1 473 ? 229.545 228.278 119.211 1.00 66.34  ? 473  TRP D CZ3 1 
ATOM   3693 C CH2 . TRP A 1 473 ? 229.391 226.895 119.054 1.00 66.34  ? 473  TRP D CH2 1 
ATOM   3694 N N   . MET A 1 474 ? 225.411 233.458 116.216 1.00 69.55  ? 474  MET D N   1 
ATOM   3695 C CA  . MET A 1 474 ? 225.074 234.831 116.575 1.00 69.55  ? 474  MET D CA  1 
ATOM   3696 C C   . MET A 1 474 ? 223.941 235.378 115.719 1.00 69.55  ? 474  MET D C   1 
ATOM   3697 O O   . MET A 1 474 ? 223.194 236.250 116.174 1.00 69.55  ? 474  MET D O   1 
ATOM   3698 C CB  . MET A 1 474 ? 226.307 235.726 116.463 1.00 69.55  ? 474  MET D CB  1 
ATOM   3699 C CG  . MET A 1 474 ? 227.296 235.542 117.597 1.00 69.55  ? 474  MET D CG  1 
ATOM   3700 S SD  . MET A 1 474 ? 227.953 233.868 117.683 1.00 69.55  ? 474  MET D SD  1 
ATOM   3701 C CE  . MET A 1 474 ? 228.697 233.725 116.061 1.00 69.55  ? 474  MET D CE  1 
ATOM   3702 N N   . LYS A 1 475 ? 223.786 234.875 114.494 1.00 66.46  ? 475  LYS D N   1 
ATOM   3703 C CA  . LYS A 1 475 ? 222.660 235.283 113.662 1.00 66.46  ? 475  LYS D CA  1 
ATOM   3704 C C   . LYS A 1 475 ? 221.338 234.960 114.349 1.00 66.46  ? 475  LYS D C   1 
ATOM   3705 O O   . LYS A 1 475 ? 220.505 235.846 114.581 1.00 66.46  ? 475  LYS D O   1 
ATOM   3706 C CB  . LYS A 1 475 ? 222.752 234.603 112.293 1.00 66.46  ? 475  LYS D CB  1 
ATOM   3707 C CG  . LYS A 1 475 ? 221.829 235.180 111.227 1.00 66.46  ? 475  LYS D CG  1 
ATOM   3708 C CD  . LYS A 1 475 ? 220.506 234.434 111.155 1.00 66.46  ? 475  LYS D CD  1 
ATOM   3709 C CE  . LYS A 1 475 ? 219.616 234.996 110.059 1.00 66.46  ? 475  LYS D CE  1 
ATOM   3710 N NZ  . LYS A 1 475 ? 220.258 234.897 108.720 1.00 66.46  ? 475  LYS D NZ  1 
ATOM   3711 N N   . LYS A 1 476 ? 221.136 233.687 114.702 1.00 65.78  ? 476  LYS D N   1 
ATOM   3712 C CA  . LYS A 1 476 ? 219.909 233.309 115.393 1.00 65.78  ? 476  LYS D CA  1 
ATOM   3713 C C   . LYS A 1 476 ? 219.851 233.897 116.797 1.00 65.78  ? 476  LYS D C   1 
ATOM   3714 O O   . LYS A 1 476 ? 218.758 234.161 117.308 1.00 65.78  ? 476  LYS D O   1 
ATOM   3715 C CB  . LYS A 1 476 ? 219.774 231.787 115.437 1.00 65.78  ? 476  LYS D CB  1 
ATOM   3716 C CG  . LYS A 1 476 ? 218.409 231.304 115.901 1.00 65.78  ? 476  LYS D CG  1 
ATOM   3717 C CD  . LYS A 1 476 ? 218.145 229.876 115.458 1.00 65.78  ? 476  LYS D CD  1 
ATOM   3718 C CE  . LYS A 1 476 ? 218.122 229.768 113.942 1.00 65.78  ? 476  LYS D CE  1 
ATOM   3719 N NZ  . LYS A 1 476 ? 217.855 228.376 113.488 1.00 65.78  ? 476  LYS D NZ  1 
ATOM   3720 N N   . TRP A 1 477 ? 221.005 234.132 117.427 1.00 61.80  ? 477  TRP D N   1 
ATOM   3721 C CA  . TRP A 1 477 ? 221.020 234.777 118.736 1.00 61.80  ? 477  TRP D CA  1 
ATOM   3722 C C   . TRP A 1 477 ? 220.413 236.172 118.666 1.00 61.80  ? 477  TRP D C   1 
ATOM   3723 O O   . TRP A 1 477 ? 219.541 236.524 119.468 1.00 61.80  ? 477  TRP D O   1 
ATOM   3724 C CB  . TRP A 1 477 ? 222.451 234.833 119.271 1.00 61.80  ? 477  TRP D CB  1 
ATOM   3725 C CG  . TRP A 1 477 ? 222.649 235.796 120.403 1.00 61.80  ? 477  TRP D CG  1 
ATOM   3726 C CD1 . TRP A 1 477 ? 223.065 237.093 120.313 1.00 61.80  ? 477  TRP D CD1 1 
ATOM   3727 C CD2 . TRP A 1 477 ? 222.450 235.537 121.798 1.00 61.80  ? 477  TRP D CD2 1 
ATOM   3728 N NE1 . TRP A 1 477 ? 223.133 237.657 121.563 1.00 61.80  ? 477  TRP D NE1 1 
ATOM   3729 C CE2 . TRP A 1 477 ? 222.762 236.722 122.492 1.00 61.80  ? 477  TRP D CE2 1 
ATOM   3730 C CE3 . TRP A 1 477 ? 222.040 234.417 122.527 1.00 61.80  ? 477  TRP D CE3 1 
ATOM   3731 C CZ2 . TRP A 1 477 ? 222.674 236.821 123.879 1.00 61.80  ? 477  TRP D CZ2 1 
ATOM   3732 C CZ3 . TRP A 1 477 ? 221.953 234.517 123.903 1.00 61.80  ? 477  TRP D CZ3 1 
ATOM   3733 C CH2 . TRP A 1 477 ? 222.269 235.710 124.564 1.00 61.80  ? 477  TRP D CH2 1 
ATOM   3734 N N   . TRP A 1 478 ? 220.860 236.980 117.703 1.00 63.98  ? 478  TRP D N   1 
ATOM   3735 C CA  . TRP A 1 478 ? 220.299 238.317 117.549 1.00 63.98  ? 478  TRP D CA  1 
ATOM   3736 C C   . TRP A 1 478 ? 218.863 238.268 117.046 1.00 63.98  ? 478  TRP D C   1 
ATOM   3737 O O   . TRP A 1 478 ? 218.049 239.113 117.432 1.00 63.98  ? 478  TRP D O   1 
ATOM   3738 C CB  . TRP A 1 478 ? 221.171 239.155 116.614 1.00 63.98  ? 478  TRP D CB  1 
ATOM   3739 C CG  . TRP A 1 478 ? 222.471 239.558 117.238 1.00 63.98  ? 478  TRP D CG  1 
ATOM   3740 C CD1 . TRP A 1 478 ? 223.722 239.200 116.831 1.00 63.98  ? 478  TRP D CD1 1 
ATOM   3741 C CD2 . TRP A 1 478 ? 222.646 240.384 118.395 1.00 63.98  ? 478  TRP D CD2 1 
ATOM   3742 N NE1 . TRP A 1 478 ? 224.666 239.759 117.658 1.00 63.98  ? 478  TRP D NE1 1 
ATOM   3743 C CE2 . TRP A 1 478 ? 224.031 240.490 118.627 1.00 63.98  ? 478  TRP D CE2 1 
ATOM   3744 C CE3 . TRP A 1 478 ? 221.766 241.048 119.256 1.00 63.98  ? 478  TRP D CE3 1 
ATOM   3745 C CZ2 . TRP A 1 478 ? 224.556 241.232 119.682 1.00 63.98  ? 478  TRP D CZ2 1 
ATOM   3746 C CZ3 . TRP A 1 478 ? 222.289 241.783 120.302 1.00 63.98  ? 478  TRP D CZ3 1 
ATOM   3747 C CH2 . TRP A 1 478 ? 223.671 241.869 120.506 1.00 63.98  ? 478  TRP D CH2 1 
ATOM   3748 N N   . GLU A 1 479 ? 218.525 237.283 116.209 1.00 66.62  ? 479  GLU D N   1 
ATOM   3749 C CA  . GLU A 1 479 ? 217.137 237.129 115.782 1.00 66.62  ? 479  GLU D CA  1 
ATOM   3750 C C   . GLU A 1 479 ? 216.220 236.895 116.979 1.00 66.62  ? 479  GLU D C   1 
ATOM   3751 O O   . GLU A 1 479 ? 215.151 237.507 117.088 1.00 66.62  ? 479  GLU D O   1 
ATOM   3752 C CB  . GLU A 1 479 ? 217.021 235.982 114.778 1.00 66.62  ? 479  GLU D CB  1 
ATOM   3753 C CG  . GLU A 1 479 ? 215.611 235.754 114.260 1.00 66.62  ? 479  GLU D CG  1 
ATOM   3754 C CD  . GLU A 1 479 ? 215.534 234.615 113.263 1.00 66.62  ? 479  GLU D CD  1 
ATOM   3755 O OE1 . GLU A 1 479 ? 216.587 234.015 112.961 1.00 66.62  ? 479  GLU D OE1 1 
ATOM   3756 O OE2 . GLU A 1 479 ? 214.420 234.320 112.781 1.00 66.62  ? 479  GLU D OE2 1 
ATOM   3757 N N   . MET A 1 480 ? 216.633 236.017 117.897 1.00 63.25  ? 480  MET D N   1 
ATOM   3758 C CA  . MET A 1 480 ? 215.832 235.753 119.088 1.00 63.25  ? 480  MET D CA  1 
ATOM   3759 C C   . MET A 1 480 ? 215.818 236.954 120.025 1.00 63.25  ? 480  MET D C   1 
ATOM   3760 O O   . MET A 1 480 ? 214.772 237.295 120.589 1.00 63.25  ? 480  MET D O   1 
ATOM   3761 C CB  . MET A 1 480 ? 216.363 234.519 119.815 1.00 63.25  ? 480  MET D CB  1 
ATOM   3762 C CG  . MET A 1 480 ? 216.238 233.227 119.030 1.00 63.25  ? 480  MET D CG  1 
ATOM   3763 S SD  . MET A 1 480 ? 217.033 231.849 119.874 1.00 63.25  ? 480  MET D SD  1 
ATOM   3764 C CE  . MET A 1 480 ? 216.118 231.820 121.412 1.00 63.25  ? 480  MET D CE  1 
ATOM   3765 N N   . LYS A 1 481 ? 216.968 237.608 120.205 1.00 62.75  ? 481  LYS D N   1 
ATOM   3766 C CA  . LYS A 1 481 ? 217.040 238.765 121.087 1.00 62.75  ? 481  LYS D CA  1 
ATOM   3767 C C   . LYS A 1 481 ? 216.245 239.947 120.551 1.00 62.75  ? 481  LYS D C   1 
ATOM   3768 O O   . LYS A 1 481 ? 215.891 240.842 121.325 1.00 62.75  ? 481  LYS D O   1 
ATOM   3769 C CB  . LYS A 1 481 ? 218.501 239.164 121.303 1.00 62.75  ? 481  LYS D CB  1 
ATOM   3770 C CG  . LYS A 1 481 ? 218.740 240.028 122.528 1.00 62.75  ? 481  LYS D CG  1 
ATOM   3771 C CD  . LYS A 1 481 ? 220.225 240.226 122.775 1.00 62.75  ? 481  LYS D CD  1 
ATOM   3772 C CE  . LYS A 1 481 ? 220.473 240.959 124.080 1.00 62.75  ? 481  LYS D CE  1 
ATOM   3773 N NZ  . LYS A 1 481 ? 219.912 240.214 125.239 1.00 62.75  ? 481  LYS D NZ  1 
ATOM   3774 N N   . ARG A 1 482 ? 215.966 239.974 119.249 1.00 64.23  ? 482  ARG D N   1 
ATOM   3775 C CA  . ARG A 1 482 ? 215.106 240.998 118.675 1.00 64.23  ? 482  ARG D CA  1 
ATOM   3776 C C   . ARG A 1 482 ? 213.642 240.582 118.650 1.00 64.23  ? 482  ARG D C   1 
ATOM   3777 O O   . ARG A 1 482 ? 212.758 241.443 118.738 1.00 64.23  ? 482  ARG D O   1 
ATOM   3778 C CB  . ARG A 1 482 ? 215.570 241.336 117.255 1.00 64.23  ? 482  ARG D CB  1 
ATOM   3779 C CG  . ARG A 1 482 ? 214.910 242.564 116.655 1.00 64.23  ? 482  ARG D CG  1 
ATOM   3780 C CD  . ARG A 1 482 ? 215.345 242.772 115.216 1.00 64.23  ? 482  ARG D CD  1 
ATOM   3781 N NE  . ARG A 1 482 ? 216.791 242.920 115.091 1.00 64.23  ? 482  ARG D NE  1 
ATOM   3782 C CZ  . ARG A 1 482 ? 217.422 243.129 113.941 1.00 64.23  ? 482  ARG D CZ  1 
ATOM   3783 N NH1 . ARG A 1 482 ? 218.742 243.252 113.917 1.00 64.23  ? 482  ARG D NH1 1 
ATOM   3784 N NH2 . ARG A 1 482 ? 216.733 243.215 112.811 1.00 64.23  ? 482  ARG D NH2 1 
ATOM   3785 N N   . GLU A 1 483 ? 213.363 239.283 118.541 1.00 63.19  ? 483  GLU D N   1 
ATOM   3786 C CA  . GLU A 1 483 ? 211.989 238.789 118.530 1.00 63.19  ? 483  GLU D CA  1 
ATOM   3787 C C   . GLU A 1 483 ? 211.469 238.545 119.945 1.00 63.19  ? 483  GLU D C   1 
ATOM   3788 O O   . GLU A 1 483 ? 210.443 239.106 120.342 1.00 63.19  ? 483  GLU D O   1 
ATOM   3789 C CB  . GLU A 1 483 ? 211.901 237.506 117.696 1.00 63.19  ? 483  GLU D CB  1 
ATOM   3790 C CG  . GLU A 1 483 ? 210.516 236.883 117.664 1.00 63.19  ? 483  GLU D CG  1 
ATOM   3791 C CD  . GLU A 1 483 ? 210.471 235.604 116.853 1.00 63.19  ? 483  GLU D CD  1 
ATOM   3792 O OE1 . GLU A 1 483 ? 211.525 235.204 116.314 1.00 63.19  ? 483  GLU D OE1 1 
ATOM   3793 O OE2 . GLU A 1 483 ? 209.384 234.998 116.755 1.00 63.19  ? 483  GLU D OE2 1 
ATOM   3794 N N   . ILE A 1 484 ? 212.167 237.707 120.713 1.00 61.13  ? 484  ILE D N   1 
ATOM   3795 C CA  . ILE A 1 484 ? 211.740 237.415 122.078 1.00 61.13  ? 484  ILE D CA  1 
ATOM   3796 C C   . ILE A 1 484 ? 211.926 238.639 122.966 1.00 61.13  ? 484  ILE D C   1 
ATOM   3797 O O   . ILE A 1 484 ? 210.986 239.097 123.627 1.00 61.13  ? 484  ILE D O   1 
ATOM   3798 C CB  . ILE A 1 484 ? 212.502 236.196 122.627 1.00 61.13  ? 484  ILE D CB  1 
ATOM   3799 C CG1 . ILE A 1 484 ? 212.184 234.951 121.797 1.00 61.13  ? 484  ILE D CG1 1 
ATOM   3800 C CG2 . ILE A 1 484 ? 212.165 235.970 124.090 1.00 61.13  ? 484  ILE D CG2 1 
ATOM   3801 C CD1 . ILE A 1 484 ? 212.939 233.717 122.235 1.00 61.13  ? 484  ILE D CD1 1 
ATOM   3802 N N   . VAL A 1 485 ? 213.136 239.182 122.996 1.00 62.76  ? 485  VAL D N   1 
ATOM   3803 C CA  . VAL A 1 485 ? 213.425 240.380 123.767 1.00 62.76  ? 485  VAL D CA  1 
ATOM   3804 C C   . VAL A 1 485 ? 213.272 241.596 122.861 1.00 62.76  ? 485  VAL D C   1 
ATOM   3805 O O   . VAL A 1 485 ? 213.271 241.493 121.632 1.00 62.76  ? 485  VAL D O   1 
ATOM   3806 C CB  . VAL A 1 485 ? 214.834 240.318 124.394 1.00 62.76  ? 485  VAL D CB  1 
ATOM   3807 C CG1 . VAL A 1 485 ? 214.917 241.203 125.628 1.00 62.76  ? 485  VAL D CG1 1 
ATOM   3808 C CG2 . VAL A 1 485 ? 215.200 238.882 124.735 1.00 62.76  ? 485  VAL D CG2 1 
ATOM   3809 N N   . GLY A 1 486 ? 213.117 242.766 123.475 1.00 64.16  ? 486  GLY D N   1 
ATOM   3810 C CA  . GLY A 1 486 ? 213.045 244.000 122.719 1.00 64.16  ? 486  GLY D CA  1 
ATOM   3811 C C   . GLY A 1 486 ? 214.394 244.673 122.577 1.00 64.16  ? 486  GLY D C   1 
ATOM   3812 O O   . GLY A 1 486 ? 214.531 245.868 122.856 1.00 64.16  ? 486  GLY D O   1 
ATOM   3813 N N   . VAL A 1 487 ? 215.399 243.917 122.141 1.00 63.89  ? 487  VAL D N   1 
ATOM   3814 C CA  . VAL A 1 487 ? 216.772 244.399 122.052 1.00 63.89  ? 487  VAL D CA  1 
ATOM   3815 C C   . VAL A 1 487 ? 217.285 244.161 120.639 1.00 63.89  ? 487  VAL D C   1 
ATOM   3816 O O   . VAL A 1 487 ? 217.208 243.040 120.126 1.00 63.89  ? 487  VAL D O   1 
ATOM   3817 C CB  . VAL A 1 487 ? 217.688 243.707 123.080 1.00 63.89  ? 487  VAL D CB  1 
ATOM   3818 C CG1 . VAL A 1 487 ? 219.116 244.206 122.938 1.00 63.89  ? 487  VAL D CG1 1 
ATOM   3819 C CG2 . VAL A 1 487 ? 217.175 243.942 124.491 1.00 63.89  ? 487  VAL D CG2 1 
ATOM   3820 N N   . VAL A 1 488 ? 217.811 245.213 120.016 1.00 65.79  ? 488  VAL D N   1 
ATOM   3821 C CA  . VAL A 1 488 ? 218.386 245.141 118.679 1.00 65.79  ? 488  VAL D CA  1 
ATOM   3822 C C   . VAL A 1 488 ? 219.854 245.538 118.767 1.00 65.79  ? 488  VAL D C   1 
ATOM   3823 O O   . VAL A 1 488 ? 220.227 246.401 119.569 1.00 65.79  ? 488  VAL D O   1 
ATOM   3824 C CB  . VAL A 1 488 ? 217.620 246.039 117.682 1.00 65.79  ? 488  VAL D CB  1 
ATOM   3825 C CG1 . VAL A 1 488 ? 217.688 247.501 118.104 1.00 65.79  ? 488  VAL D CG1 1 
ATOM   3826 C CG2 . VAL A 1 488 ? 218.146 245.852 116.265 1.00 65.79  ? 488  VAL D CG2 1 
ATOM   3827 N N   . GLU A 1 489 ? 220.691 244.890 117.955 1.00 68.93  ? 489  GLU D N   1 
ATOM   3828 C CA  . GLU A 1 489 ? 222.115 245.190 117.990 1.00 68.93  ? 489  GLU D CA  1 
ATOM   3829 C C   . GLU A 1 489 ? 222.402 246.492 117.242 1.00 68.93  ? 489  GLU D C   1 
ATOM   3830 O O   . GLU A 1 489 ? 221.783 246.768 116.211 1.00 68.93  ? 489  GLU D O   1 
ATOM   3831 C CB  . GLU A 1 489 ? 222.930 244.046 117.382 1.00 68.93  ? 489  GLU D CB  1 
ATOM   3832 C CG  . GLU A 1 489 ? 222.682 243.786 115.900 1.00 68.93  ? 489  GLU D CG  1 
ATOM   3833 C CD  . GLU A 1 489 ? 221.399 243.021 115.638 1.00 68.93  ? 489  GLU D CD  1 
ATOM   3834 O OE1 . GLU A 1 489 ? 220.759 242.574 116.612 1.00 68.93  ? 489  GLU D OE1 1 
ATOM   3835 O OE2 . GLU A 1 489 ? 221.031 242.867 114.454 1.00 68.93  ? 489  GLU D OE2 1 
ATOM   3836 N N   . PRO A 1 490 ? 223.316 247.318 117.752 1.00 70.99  ? 490  PRO D N   1 
ATOM   3837 C CA  . PRO A 1 490 ? 223.636 248.581 117.071 1.00 70.99  ? 490  PRO D CA  1 
ATOM   3838 C C   . PRO A 1 490 ? 224.327 248.373 115.733 1.00 70.99  ? 490  PRO D C   1 
ATOM   3839 O O   . PRO A 1 490 ? 223.911 248.940 114.718 1.00 70.99  ? 490  PRO D O   1 
ATOM   3840 C CB  . PRO A 1 490 ? 224.560 249.294 118.068 1.00 70.99  ? 490  PRO D CB  1 
ATOM   3841 C CG  . PRO A 1 490 ? 224.305 248.629 119.384 1.00 70.99  ? 490  PRO D CG  1 
ATOM   3842 C CD  . PRO A 1 490 ? 223.990 247.206 119.055 1.00 70.99  ? 490  PRO D CD  1 
ATOM   3843 N N   . VAL A 1 491 ? 225.382 247.564 115.720 1.00 71.21  ? 491  VAL D N   1 
ATOM   3844 C CA  . VAL A 1 491 ? 226.163 247.328 114.508 1.00 71.21  ? 491  VAL D CA  1 
ATOM   3845 C C   . VAL A 1 491 ? 226.094 245.848 114.149 1.00 71.21  ? 491  VAL D C   1 
ATOM   3846 O O   . VAL A 1 491 ? 225.932 245.002 115.041 1.00 71.21  ? 491  VAL D O   1 
ATOM   3847 C CB  . VAL A 1 491 ? 227.617 247.793 114.684 1.00 71.21  ? 491  VAL D CB  1 
ATOM   3848 C CG1 . VAL A 1 491 ? 227.670 249.299 114.891 1.00 71.21  ? 491  VAL D CG1 1 
ATOM   3849 C CG2 . VAL A 1 491 ? 228.269 247.071 115.850 1.00 71.21  ? 491  VAL D CG2 1 
ATOM   3850 N N   . PRO A 1 492 ? 226.197 245.489 112.869 1.00 71.64  ? 492  PRO D N   1 
ATOM   3851 C CA  . PRO A 1 492 ? 226.124 244.071 112.494 1.00 71.64  ? 492  PRO D CA  1 
ATOM   3852 C C   . PRO A 1 492 ? 227.356 243.314 112.969 1.00 71.64  ? 492  PRO D C   1 
ATOM   3853 O O   . PRO A 1 492 ? 228.491 243.733 112.731 1.00 71.64  ? 492  PRO D O   1 
ATOM   3854 C CB  . PRO A 1 492 ? 226.043 244.109 110.962 1.00 71.64  ? 492  PRO D CB  1 
ATOM   3855 C CG  . PRO A 1 492 ? 225.649 245.517 110.621 1.00 71.64  ? 492  PRO D CG  1 
ATOM   3856 C CD  . PRO A 1 492 ? 226.256 246.367 111.690 1.00 71.64  ? 492  PRO D CD  1 
ATOM   3857 N N   . HIS A 1 493 ? 227.123 242.193 113.644 1.00 72.59  ? 493  HIS D N   1 
ATOM   3858 C CA  . HIS A 1 493 ? 228.185 241.317 114.122 1.00 72.59  ? 493  HIS D CA  1 
ATOM   3859 C C   . HIS A 1 493 ? 228.145 240.021 113.324 1.00 72.59  ? 493  HIS D C   1 
ATOM   3860 O O   . HIS A 1 493 ? 227.125 239.323 113.317 1.00 72.59  ? 493  HIS D O   1 
ATOM   3861 C CB  . HIS A 1 493 ? 228.037 241.035 115.617 1.00 72.59  ? 493  HIS D CB  1 
ATOM   3862 C CG  . HIS A 1 493 ? 228.381 242.201 116.489 1.00 72.59  ? 493  HIS D CG  1 
ATOM   3863 N ND1 . HIS A 1 493 ? 228.411 242.118 117.864 1.00 72.59  ? 493  HIS D ND1 1 
ATOM   3864 C CD2 . HIS A 1 493 ? 228.715 243.477 116.181 1.00 72.59  ? 493  HIS D CD2 1 
ATOM   3865 C CE1 . HIS A 1 493 ? 228.746 243.293 118.366 1.00 72.59  ? 493  HIS D CE1 1 
ATOM   3866 N NE2 . HIS A 1 493 ? 228.936 244.135 117.367 1.00 72.59  ? 493  HIS D NE2 1 
ATOM   3867 N N   . ASP A 1 494 ? 229.250 239.704 112.656 1.00 75.13  ? 494  ASP D N   1 
ATOM   3868 C CA  . ASP A 1 494 ? 229.338 238.492 111.854 1.00 75.13  ? 494  ASP D CA  1 
ATOM   3869 C C   . ASP A 1 494 ? 229.640 237.303 112.766 1.00 75.13  ? 494  ASP D C   1 
ATOM   3870 O O   . ASP A 1 494 ? 229.560 237.392 113.994 1.00 75.13  ? 494  ASP D O   1 
ATOM   3871 C CB  . ASP A 1 494 ? 230.378 238.662 110.749 1.00 75.13  ? 494  ASP D CB  1 
ATOM   3872 C CG  . ASP A 1 494 ? 231.798 238.627 111.272 1.00 75.13  ? 494  ASP D CG  1 
ATOM   3873 O OD1 . ASP A 1 494 ? 232.355 237.516 111.401 1.00 75.13  ? 494  ASP D OD1 1 
ATOM   3874 O OD2 . ASP A 1 494 ? 232.357 239.707 111.552 1.00 75.13  ? 494  ASP D OD2 1 
ATOM   3875 N N   . GLU A 1 495 ? 229.997 236.168 112.167 1.00 73.49  ? 495  GLU D N   1 
ATOM   3876 C CA  . GLU A 1 495 ? 230.186 234.931 112.916 1.00 73.49  ? 495  GLU D CA  1 
ATOM   3877 C C   . GLU A 1 495 ? 231.435 234.931 113.789 1.00 73.49  ? 495  GLU D C   1 
ATOM   3878 O O   . GLU A 1 495 ? 231.641 233.962 114.527 1.00 73.49  ? 495  GLU D O   1 
ATOM   3879 C CB  . GLU A 1 495 ? 230.230 233.743 111.953 1.00 73.49  ? 495  GLU D CB  1 
ATOM   3880 C CG  . GLU A 1 495 ? 228.998 233.621 111.071 1.00 73.49  ? 495  GLU D CG  1 
ATOM   3881 C CD  . GLU A 1 495 ? 227.723 233.423 111.869 1.00 73.49  ? 495  GLU D CD  1 
ATOM   3882 O OE1 . GLU A 1 495 ? 227.783 232.798 112.949 1.00 73.49  ? 495  GLU D OE1 1 
ATOM   3883 O OE2 . GLU A 1 495 ? 226.659 233.894 111.416 1.00 73.49  ? 495  GLU D OE2 1 
ATOM   3884 N N   . THR A 1 496 ? 232.269 235.970 113.735 1.00 72.68  ? 496  THR D N   1 
ATOM   3885 C CA  . THR A 1 496 ? 233.465 236.012 114.567 1.00 72.68  ? 496  THR D CA  1 
ATOM   3886 C C   . THR A 1 496 ? 233.248 236.736 115.888 1.00 72.68  ? 496  THR D C   1 
ATOM   3887 O O   . THR A 1 496 ? 234.076 236.597 116.795 1.00 72.68  ? 496  THR D O   1 
ATOM   3888 C CB  . THR A 1 496 ? 234.624 236.676 113.814 1.00 72.68  ? 496  THR D CB  1 
ATOM   3889 O OG1 . THR A 1 496 ? 235.853 236.412 114.502 1.00 72.68  ? 496  THR D OG1 1 
ATOM   3890 C CG2 . THR A 1 496 ? 234.420 238.180 113.732 1.00 72.68  ? 496  THR D CG2 1 
ATOM   3891 N N   . TYR A 1 497 ? 232.162 237.497 116.023 1.00 73.03  ? 497  TYR D N   1 
ATOM   3892 C CA  . TYR A 1 497 ? 231.863 238.220 117.259 1.00 73.03  ? 497  TYR D CA  1 
ATOM   3893 C C   . TYR A 1 497 ? 230.937 237.356 118.104 1.00 73.03  ? 497  TYR D C   1 
ATOM   3894 O O   . TYR A 1 497 ? 229.714 237.482 118.049 1.00 73.03  ? 497  TYR D O   1 
ATOM   3895 C CB  . TYR A 1 497 ? 231.235 239.576 116.959 1.00 73.03  ? 497  TYR D CB  1 
ATOM   3896 C CG  . TYR A 1 497 ? 232.132 240.530 116.205 1.00 73.03  ? 497  TYR D CG  1 
ATOM   3897 C CD1 . TYR A 1 497 ? 232.068 240.627 114.822 1.00 73.03  ? 497  TYR D CD1 1 
ATOM   3898 C CD2 . TYR A 1 497 ? 233.035 241.342 116.878 1.00 73.03  ? 497  TYR D CD2 1 
ATOM   3899 C CE1 . TYR A 1 497 ? 232.883 241.501 114.129 1.00 73.03  ? 497  TYR D CE1 1 
ATOM   3900 C CE2 . TYR A 1 497 ? 233.855 242.219 116.193 1.00 73.03  ? 497  TYR D CE2 1 
ATOM   3901 C CZ  . TYR A 1 497 ? 233.775 242.294 114.819 1.00 73.03  ? 497  TYR D CZ  1 
ATOM   3902 O OH  . TYR A 1 497 ? 234.589 243.166 114.133 1.00 73.03  ? 497  TYR D OH  1 
ATOM   3903 N N   . CYS A 1 498 ? 231.527 236.471 118.908 1.00 68.04  ? 498  CYS D N   1 
ATOM   3904 C CA  . CYS A 1 498 ? 230.756 235.574 119.768 1.00 68.04  ? 498  CYS D CA  1 
ATOM   3905 C C   . CYS A 1 498 ? 230.211 236.379 120.945 1.00 68.04  ? 498  CYS D C   1 
ATOM   3906 O O   . CYS A 1 498 ? 230.730 236.350 122.063 1.00 68.04  ? 498  CYS D O   1 
ATOM   3907 C CB  . CYS A 1 498 ? 231.611 234.403 120.235 1.00 68.04  ? 498  CYS D CB  1 
ATOM   3908 S SG  . CYS A 1 498 ? 230.692 233.113 121.105 1.00 68.04  ? 498  CYS D SG  1 
ATOM   3909 N N   . ASP A 1 499 ? 229.137 237.114 120.674 1.00 66.91  ? 499  ASP D N   1 
ATOM   3910 C CA  . ASP A 1 499 ? 228.474 237.973 121.649 1.00 66.91  ? 499  ASP D CA  1 
ATOM   3911 C C   . ASP A 1 499 ? 227.849 237.204 122.814 1.00 66.91  ? 499  ASP D C   1 
ATOM   3912 O O   . ASP A 1 499 ? 227.938 237.673 123.956 1.00 66.91  ? 499  ASP D O   1 
ATOM   3913 C CB  . ASP A 1 499 ? 227.408 238.825 120.954 1.00 66.91  ? 499  ASP D CB  1 
ATOM   3914 C CG  . ASP A 1 499 ? 227.992 239.732 119.891 1.00 66.91  ? 499  ASP D CG  1 
ATOM   3915 O OD1 . ASP A 1 499 ? 229.122 240.228 120.086 1.00 66.91  ? 499  ASP D OD1 1 
ATOM   3916 O OD2 . ASP A 1 499 ? 227.325 239.949 118.858 1.00 66.91  ? 499  ASP D OD2 1 
ATOM   3917 N N   . PRO A 1 500 ? 227.195 236.052 122.591 1.00 62.64  ? 500  PRO D N   1 
ATOM   3918 C CA  . PRO A 1 500 ? 226.601 235.343 123.741 1.00 62.64  ? 500  PRO D CA  1 
ATOM   3919 C C   . PRO A 1 500 ? 227.605 234.966 124.815 1.00 62.64  ? 500  PRO D C   1 
ATOM   3920 O O   . PRO A 1 500 ? 227.281 235.038 126.006 1.00 62.64  ? 500  PRO D O   1 
ATOM   3921 C CB  . PRO A 1 500 ? 225.973 234.101 123.095 1.00 62.64  ? 500  PRO D CB  1 
ATOM   3922 C CG  . PRO A 1 500 ? 225.682 234.510 121.713 1.00 62.64  ? 500  PRO D CG  1 
ATOM   3923 C CD  . PRO A 1 500 ? 226.801 235.419 121.317 1.00 62.64  ? 500  PRO D CD  1 
ATOM   3924 N N   . ALA A 1 501 ? 228.820 234.577 124.434 1.00 62.14  ? 501  ALA D N   1 
ATOM   3925 C CA  . ALA A 1 501 ? 229.832 234.137 125.394 1.00 62.14  ? 501  ALA D CA  1 
ATOM   3926 C C   . ALA A 1 501 ? 230.425 235.275 126.216 1.00 62.14  ? 501  ALA D C   1 
ATOM   3927 O O   . ALA A 1 501 ? 231.372 235.018 126.970 1.00 62.14  ? 501  ALA D O   1 
ATOM   3928 C CB  . ALA A 1 501 ? 230.950 233.389 124.669 1.00 62.14  ? 501  ALA D CB  1 
ATOM   3929 N N   . SER A 1 502 ? 229.929 236.506 126.114 1.00 61.55  ? 502  SER D N   1 
ATOM   3930 C CA  . SER A 1 502 ? 230.470 237.626 126.875 1.00 61.55  ? 502  SER D CA  1 
ATOM   3931 C C   . SER A 1 502 ? 229.912 237.711 128.291 1.00 61.55  ? 502  SER D C   1 
ATOM   3932 O O   . SER A 1 502 ? 230.213 238.676 129.000 1.00 61.55  ? 502  SER D O   1 
ATOM   3933 C CB  . SER A 1 502 ? 230.203 238.939 126.134 1.00 61.55  ? 502  SER D CB  1 
ATOM   3934 O OG  . SER A 1 502 ? 228.814 239.153 125.959 1.00 61.55  ? 502  SER D OG  1 
ATOM   3935 N N   . LEU A 1 503 ? 229.116 236.736 128.717 1.00 59.64  ? 503  LEU D N   1 
ATOM   3936 C CA  . LEU A 1 503 ? 228.522 236.728 130.044 1.00 59.64  ? 503  LEU D CA  1 
ATOM   3937 C C   . LEU A 1 503 ? 229.272 235.762 130.956 1.00 59.64  ? 503  LEU D C   1 
ATOM   3938 O O   . LEU A 1 503 ? 229.918 234.814 130.504 1.00 59.64  ? 503  LEU D O   1 
ATOM   3939 C CB  . LEU A 1 503 ? 227.039 236.350 129.968 1.00 59.64  ? 503  LEU D CB  1 
ATOM   3940 C CG  . LEU A 1 503 ? 226.186 236.522 131.228 1.00 59.64  ? 503  LEU D CG  1 
ATOM   3941 C CD1 . LEU A 1 503 ? 226.252 237.954 131.729 1.00 59.64  ? 503  LEU D CD1 1 
ATOM   3942 C CD2 . LEU A 1 503 ? 224.748 236.112 130.962 1.00 59.64  ? 503  LEU D CD2 1 
ATOM   3943 N N   . PHE A 1 504 ? 229.180 236.023 132.263 1.00 57.59  ? 504  PHE D N   1 
ATOM   3944 C CA  . PHE A 1 504 ? 229.894 235.205 133.238 1.00 57.59  ? 504  PHE D CA  1 
ATOM   3945 C C   . PHE A 1 504 ? 229.325 233.793 133.311 1.00 57.59  ? 504  PHE D C   1 
ATOM   3946 O O   . PHE A 1 504 ? 230.082 232.816 133.338 1.00 57.59  ? 504  PHE D O   1 
ATOM   3947 C CB  . PHE A 1 504 ? 229.845 235.875 134.613 1.00 57.59  ? 504  PHE D CB  1 
ATOM   3948 C CG  . PHE A 1 504 ? 230.419 235.037 135.721 1.00 57.59  ? 504  PHE D CG  1 
ATOM   3949 C CD1 . PHE A 1 504 ? 231.785 234.993 135.938 1.00 57.59  ? 504  PHE D CD1 1 
ATOM   3950 C CD2 . PHE A 1 504 ? 229.590 234.303 136.554 1.00 57.59  ? 504  PHE D CD2 1 
ATOM   3951 C CE1 . PHE A 1 504 ? 232.315 234.226 136.958 1.00 57.59  ? 504  PHE D CE1 1 
ATOM   3952 C CE2 . PHE A 1 504 ? 230.114 233.534 137.575 1.00 57.59  ? 504  PHE D CE2 1 
ATOM   3953 C CZ  . PHE A 1 504 ? 231.478 233.496 137.778 1.00 57.59  ? 504  PHE D CZ  1 
ATOM   3954 N N   . HIS A 1 505 ? 227.997 233.663 133.343 1.00 57.82  ? 505  HIS D N   1 
ATOM   3955 C CA  . HIS A 1 505 ? 227.389 232.353 133.554 1.00 57.82  ? 505  HIS D CA  1 
ATOM   3956 C C   . HIS A 1 505 ? 227.554 231.442 132.345 1.00 57.82  ? 505  HIS D C   1 
ATOM   3957 O O   . HIS A 1 505 ? 227.543 230.214 132.493 1.00 57.82  ? 505  HIS D O   1 
ATOM   3958 C CB  . HIS A 1 505 ? 225.908 232.512 133.898 1.00 57.82  ? 505  HIS D CB  1 
ATOM   3959 C CG  . HIS A 1 505 ? 225.663 233.210 135.199 1.00 57.82  ? 505  HIS D CG  1 
ATOM   3960 N ND1 . HIS A 1 505 ? 225.827 234.569 135.357 1.00 57.82  ? 505  HIS D ND1 1 
ATOM   3961 C CD2 . HIS A 1 505 ? 225.272 232.736 136.405 1.00 57.82  ? 505  HIS D CD2 1 
ATOM   3962 C CE1 . HIS A 1 505 ? 225.544 234.903 136.603 1.00 57.82  ? 505  HIS D CE1 1 
ATOM   3963 N NE2 . HIS A 1 505 ? 225.205 233.809 137.260 1.00 57.82  ? 505  HIS D NE2 1 
ATOM   3964 N N   . VAL A 1 506 ? 227.709 232.009 131.152 1.00 57.65  ? 506  VAL D N   1 
ATOM   3965 C CA  . VAL A 1 506 ? 227.860 231.188 129.957 1.00 57.65  ? 506  VAL D CA  1 
ATOM   3966 C C   . VAL A 1 506 ? 229.324 230.837 129.690 1.00 57.65  ? 506  VAL D C   1 
ATOM   3967 O O   . VAL A 1 506 ? 229.610 229.787 129.107 1.00 57.65  ? 506  VAL D O   1 
ATOM   3968 C CB  . VAL A 1 506 ? 227.224 231.897 128.748 1.00 57.65  ? 506  VAL D CB  1 
ATOM   3969 C CG1 . VAL A 1 506 ? 227.964 233.182 128.436 1.00 57.65  ? 506  VAL D CG1 1 
ATOM   3970 C CG2 . VAL A 1 506 ? 227.190 230.977 127.534 1.00 57.65  ? 506  VAL D CG2 1 
ATOM   3971 N N   . SER A 1 507 ? 230.258 231.681 130.121 1.00 57.80  ? 507  SER D N   1 
ATOM   3972 C CA  . SER A 1 507 ? 231.680 231.433 129.926 1.00 57.80  ? 507  SER D CA  1 
ATOM   3973 C C   . SER A 1 507 ? 232.323 230.714 131.104 1.00 57.80  ? 507  SER D C   1 
ATOM   3974 O O   . SER A 1 507 ? 233.541 230.510 131.095 1.00 57.80  ? 507  SER D O   1 
ATOM   3975 C CB  . SER A 1 507 ? 232.414 232.752 129.667 1.00 57.80  ? 507  SER D CB  1 
ATOM   3976 O OG  . SER A 1 507 ? 231.926 233.385 128.497 1.00 57.80  ? 507  SER D OG  1 
ATOM   3977 N N   . ASN A 1 508 ? 231.539 230.323 132.112 1.00 57.80  ? 508  ASN D N   1 
ATOM   3978 C CA  . ASN A 1 508 ? 232.065 229.619 133.276 1.00 57.80  ? 508  ASN D CA  1 
ATOM   3979 C C   . ASN A 1 508 ? 231.286 228.340 133.566 1.00 57.80  ? 508  ASN D C   1 
ATOM   3980 O O   . ASN A 1 508 ? 231.411 227.783 134.662 1.00 57.80  ? 508  ASN D O   1 
ATOM   3981 C CB  . ASN A 1 508 ? 232.065 230.528 134.508 1.00 57.80  ? 508  ASN D CB  1 
ATOM   3982 C CG  . ASN A 1 508 ? 233.000 231.712 134.358 1.00 57.80  ? 508  ASN D CG  1 
ATOM   3983 O OD1 . ASN A 1 508 ? 234.132 231.687 134.839 1.00 57.80  ? 508  ASN D OD1 1 
ATOM   3984 N ND2 . ASN A 1 508 ? 232.531 232.755 133.685 1.00 57.80  ? 508  ASN D ND2 1 
ATOM   3985 N N   . ASP A 1 509 ? 230.488 227.869 132.606 1.00 60.77  ? 509  ASP D N   1 
ATOM   3986 C CA  . ASP A 1 509 ? 229.730 226.622 132.726 1.00 60.77  ? 509  ASP D CA  1 
ATOM   3987 C C   . ASP A 1 509 ? 228.777 226.668 133.925 1.00 60.77  ? 509  ASP D C   1 
ATOM   3988 O O   . ASP A 1 509 ? 228.895 225.902 134.883 1.00 60.77  ? 509  ASP D O   1 
ATOM   3989 C CB  . ASP A 1 509 ? 230.675 225.417 132.810 1.00 60.77  ? 509  ASP D CB  1 
ATOM   3990 C CG  . ASP A 1 509 ? 229.956 224.095 132.631 1.00 60.77  ? 509  ASP D CG  1 
ATOM   3991 O OD1 . ASP A 1 509 ? 228.757 224.108 132.283 1.00 60.77  ? 509  ASP D OD1 1 
ATOM   3992 O OD2 . ASP A 1 509 ? 230.591 223.040 132.839 1.00 60.77  ? 509  ASP D OD2 1 
ATOM   3993 N N   . TYR A 1 510 ? 227.823 227.593 133.852 1.00 57.57  ? 510  TYR D N   1 
ATOM   3994 C CA  . TYR A 1 510 ? 226.793 227.744 134.869 1.00 57.57  ? 510  TYR D CA  1 
ATOM   3995 C C   . TYR A 1 510 ? 225.421 227.767 134.211 1.00 57.57  ? 510  TYR D C   1 
ATOM   3996 O O   . TYR A 1 510 ? 225.240 228.378 133.154 1.00 57.57  ? 510  TYR D O   1 
ATOM   3997 C CB  . TYR A 1 510 ? 226.994 229.023 135.693 1.00 57.57  ? 510  TYR D CB  1 
ATOM   3998 C CG  . TYR A 1 510 ? 228.062 228.912 136.758 1.00 57.57  ? 510  TYR D CG  1 
ATOM   3999 C CD1 . TYR A 1 510 ? 227.765 228.398 138.013 1.00 57.57  ? 510  TYR D CD1 1 
ATOM   4000 C CD2 . TYR A 1 510 ? 229.363 229.326 136.511 1.00 57.57  ? 510  TYR D CD2 1 
ATOM   4001 C CE1 . TYR A 1 510 ? 228.736 228.296 138.991 1.00 57.57  ? 510  TYR D CE1 1 
ATOM   4002 C CE2 . TYR A 1 510 ? 230.340 229.228 137.483 1.00 57.57  ? 510  TYR D CE2 1 
ATOM   4003 C CZ  . TYR A 1 510 ? 230.021 228.712 138.720 1.00 57.57  ? 510  TYR D CZ  1 
ATOM   4004 O OH  . TYR A 1 510 ? 230.990 228.612 139.691 1.00 57.57  ? 510  TYR D OH  1 
ATOM   4005 N N   . SER A 1 511 ? 224.460 227.098 134.842 1.00 56.24  ? 511  SER D N   1 
ATOM   4006 C CA  . SER A 1 511 ? 223.094 227.097 134.343 1.00 56.24  ? 511  SER D CA  1 
ATOM   4007 C C   . SER A 1 511 ? 222.449 228.464 134.555 1.00 56.24  ? 511  SER D C   1 
ATOM   4008 O O   . SER A 1 511 ? 222.856 229.249 135.416 1.00 56.24  ? 511  SER D O   1 
ATOM   4009 C CB  . SER A 1 511 ? 222.271 226.010 135.034 1.00 56.24  ? 511  SER D CB  1 
ATOM   4010 O OG  . SER A 1 511 ? 220.942 225.988 134.543 1.00 56.24  ? 511  SER D OG  1 
ATOM   4011 N N   . PHE A 1 512 ? 221.422 228.745 133.753 1.00 54.68  ? 512  PHE D N   1 
ATOM   4012 C CA  . PHE A 1 512 ? 220.767 230.047 133.780 1.00 54.68  ? 512  PHE D CA  1 
ATOM   4013 C C   . PHE A 1 512 ? 219.262 229.993 134.000 1.00 54.68  ? 512  PHE D C   1 
ATOM   4014 O O   . PHE A 1 512 ? 218.696 230.995 134.453 1.00 54.68  ? 512  PHE D O   1 
ATOM   4015 C CB  . PHE A 1 512 ? 221.049 230.813 132.479 1.00 54.68  ? 512  PHE D CB  1 
ATOM   4016 C CG  . PHE A 1 512 ? 221.218 232.292 132.671 1.00 54.68  ? 512  PHE D CG  1 
ATOM   4017 C CD1 . PHE A 1 512 ? 222.381 232.801 133.224 1.00 54.68  ? 512  PHE D CD1 1 
ATOM   4018 C CD2 . PHE A 1 512 ? 220.221 233.174 132.294 1.00 54.68  ? 512  PHE D CD2 1 
ATOM   4019 C CE1 . PHE A 1 512 ? 222.543 234.161 133.402 1.00 54.68  ? 512  PHE D CE1 1 
ATOM   4020 C CE2 . PHE A 1 512 ? 220.378 234.535 132.469 1.00 54.68  ? 512  PHE D CE2 1 
ATOM   4021 C CZ  . PHE A 1 512 ? 221.541 235.029 133.023 1.00 54.68  ? 512  PHE D CZ  1 
ATOM   4022 N N   . ILE A 1 513 ? 218.595 228.874 133.704 1.00 55.30  ? 513  ILE D N   1 
ATOM   4023 C CA  . ILE A 1 513 ? 217.153 228.785 133.914 1.00 55.30  ? 513  ILE D CA  1 
ATOM   4024 C C   . ILE A 1 513 ? 216.800 228.809 135.396 1.00 55.30  ? 513  ILE D C   1 
ATOM   4025 O O   . ILE A 1 513 ? 215.631 229.025 135.753 1.00 55.30  ? 513  ILE D O   1 
ATOM   4026 C CB  . ILE A 1 513 ? 216.595 227.519 133.234 1.00 55.30  ? 513  ILE D CB  1 
ATOM   4027 C CG1 . ILE A 1 513 ? 215.088 227.647 133.004 1.00 55.30  ? 513  ILE D CG1 1 
ATOM   4028 C CG2 . ILE A 1 513 ? 216.910 226.283 134.063 1.00 55.30  ? 513  ILE D CG2 1 
ATOM   4029 C CD1 . ILE A 1 513 ? 214.706 228.804 132.108 1.00 55.30  ? 513  ILE D CD1 1 
ATOM   4030 N N   . ARG A 1 514 ? 217.787 228.595 136.272 1.00 54.05  ? 514  ARG D N   1 
ATOM   4031 C CA  . ARG A 1 514 ? 217.535 228.649 137.707 1.00 54.05  ? 514  ARG D CA  1 
ATOM   4032 C C   . ARG A 1 514 ? 216.990 230.006 138.129 1.00 54.05  ? 514  ARG D C   1 
ATOM   4033 O O   . ARG A 1 514 ? 216.166 230.083 139.045 1.00 54.05  ? 514  ARG D O   1 
ATOM   4034 C CB  . ARG A 1 514 ? 218.813 228.323 138.482 1.00 54.05  ? 514  ARG D CB  1 
ATOM   4035 C CG  . ARG A 1 514 ? 219.983 229.245 138.179 1.00 54.05  ? 514  ARG D CG  1 
ATOM   4036 C CD  . ARG A 1 514 ? 221.146 228.997 139.126 1.00 54.05  ? 514  ARG D CD  1 
ATOM   4037 N NE  . ARG A 1 514 ? 221.671 227.641 139.010 1.00 54.05  ? 514  ARG D NE  1 
ATOM   4038 C CZ  . ARG A 1 514 ? 222.684 227.170 139.730 1.00 54.05  ? 514  ARG D CZ  1 
ATOM   4039 N NH1 . ARG A 1 514 ? 223.098 225.922 139.559 1.00 54.05  ? 514  ARG D NH1 1 
ATOM   4040 N NH2 . ARG A 1 514 ? 223.283 227.946 140.622 1.00 54.05  ? 514  ARG D NH2 1 
ATOM   4041 N N   . TYR A 1 515 ? 217.413 231.082 137.461 1.00 53.50  ? 515  TYR D N   1 
ATOM   4042 C CA  . TYR A 1 515 ? 216.924 232.409 137.819 1.00 53.50  ? 515  TYR D CA  1 
ATOM   4043 C C   . TYR A 1 515 ? 215.452 232.574 137.459 1.00 53.50  ? 515  TYR D C   1 
ATOM   4044 O O   . TYR A 1 515 ? 214.673 233.114 138.251 1.00 53.50  ? 515  TYR D O   1 
ATOM   4045 C CB  . TYR A 1 515 ? 217.780 233.479 137.144 1.00 53.50  ? 515  TYR D CB  1 
ATOM   4046 C CG  . TYR A 1 515 ? 219.235 233.415 137.549 1.00 53.50  ? 515  TYR D CG  1 
ATOM   4047 C CD1 . TYR A 1 515 ? 219.659 233.932 138.765 1.00 53.50  ? 515  TYR D CD1 1 
ATOM   4048 C CD2 . TYR A 1 515 ? 220.182 232.828 136.720 1.00 53.50  ? 515  TYR D CD2 1 
ATOM   4049 C CE1 . TYR A 1 515 ? 220.985 233.871 139.144 1.00 53.50  ? 515  TYR D CE1 1 
ATOM   4050 C CE2 . TYR A 1 515 ? 221.511 232.764 137.090 1.00 53.50  ? 515  TYR D CE2 1 
ATOM   4051 C CZ  . TYR A 1 515 ? 221.907 233.287 138.303 1.00 53.50  ? 515  TYR D CZ  1 
ATOM   4052 O OH  . TYR A 1 515 ? 223.229 233.226 138.676 1.00 53.50  ? 515  TYR D OH  1 
ATOM   4053 N N   . TYR A 1 516 ? 215.050 232.104 136.277 1.00 54.81  ? 516  TYR D N   1 
ATOM   4054 C CA  . TYR A 1 516 ? 213.639 232.138 135.901 1.00 54.81  ? 516  TYR D CA  1 
ATOM   4055 C C   . TYR A 1 516 ? 212.799 231.303 136.863 1.00 54.81  ? 516  TYR D C   1 
ATOM   4056 O O   . TYR A 1 516 ? 211.732 231.738 137.327 1.00 54.81  ? 516  TYR D O   1 
ATOM   4057 C CB  . TYR A 1 516 ? 213.485 231.637 134.463 1.00 54.81  ? 516  TYR D CB  1 
ATOM   4058 C CG  . TYR A 1 516 ? 212.122 231.857 133.847 1.00 54.81  ? 516  TYR D CG  1 
ATOM   4059 C CD1 . TYR A 1 516 ? 211.113 230.913 133.986 1.00 54.81  ? 516  TYR D CD1 1 
ATOM   4060 C CD2 . TYR A 1 516 ? 211.851 233.000 133.107 1.00 54.81  ? 516  TYR D CD2 1 
ATOM   4061 C CE1 . TYR A 1 516 ? 209.870 231.108 133.417 1.00 54.81  ? 516  TYR D CE1 1 
ATOM   4062 C CE2 . TYR A 1 516 ? 210.611 233.204 132.535 1.00 54.81  ? 516  TYR D CE2 1 
ATOM   4063 C CZ  . TYR A 1 516 ? 209.624 232.255 132.693 1.00 54.81  ? 516  TYR D CZ  1 
ATOM   4064 O OH  . TYR A 1 516 ? 208.388 232.454 132.125 1.00 54.81  ? 516  TYR D OH  1 
ATOM   4065 N N   . THR A 1 517 ? 213.276 230.096 137.183 1.00 53.51  ? 517  THR D N   1 
ATOM   4066 C CA  . THR A 1 517 ? 212.523 229.224 138.078 1.00 53.51  ? 517  THR D CA  1 
ATOM   4067 C C   . THR A 1 517 ? 212.396 229.832 139.469 1.00 53.51  ? 517  THR D C   1 
ATOM   4068 O O   . THR A 1 517 ? 211.319 229.788 140.073 1.00 53.51  ? 517  THR D O   1 
ATOM   4069 C CB  . THR A 1 517 ? 213.177 227.845 138.152 1.00 53.51  ? 517  THR D CB  1 
ATOM   4070 O OG1 . THR A 1 517 ? 214.531 227.977 138.600 1.00 53.51  ? 517  THR D OG1 1 
ATOM   4071 C CG2 . THR A 1 517 ? 213.157 227.177 136.786 1.00 53.51  ? 517  THR D CG2 1 
ATOM   4072 N N   . ARG A 1 518 ? 213.477 230.417 139.993 1.00 52.91  ? 518  ARG D N   1 
ATOM   4073 C CA  . ARG A 1 518 ? 213.406 231.024 141.317 1.00 52.91  ? 518  ARG D CA  1 
ATOM   4074 C C   . ARG A 1 518 ? 212.558 232.288 141.305 1.00 52.91  ? 518  ARG D C   1 
ATOM   4075 O O   . ARG A 1 518 ? 211.908 232.600 142.306 1.00 52.91  ? 518  ARG D O   1 
ATOM   4076 C CB  . ARG A 1 518 ? 214.814 231.315 141.848 1.00 52.91  ? 518  ARG D CB  1 
ATOM   4077 C CG  . ARG A 1 518 ? 215.517 232.500 141.206 1.00 52.91  ? 518  ARG D CG  1 
ATOM   4078 C CD  . ARG A 1 518 ? 215.503 233.721 142.115 1.00 52.91  ? 518  ARG D CD  1 
ATOM   4079 N NE  . ARG A 1 518 ? 215.821 234.948 141.390 1.00 52.91  ? 518  ARG D NE  1 
ATOM   4080 C CZ  . ARG A 1 518 ? 217.055 235.384 141.159 1.00 52.91  ? 518  ARG D CZ  1 
ATOM   4081 N NH1 . ARG A 1 518 ? 217.246 236.513 140.491 1.00 52.91  ? 518  ARG D NH1 1 
ATOM   4082 N NH2 . ARG A 1 518 ? 218.098 234.690 141.592 1.00 52.91  ? 518  ARG D NH2 1 
ATOM   4083 N N   . THR A 1 519 ? 212.533 233.014 140.183 1.00 52.27  ? 519  THR D N   1 
ATOM   4084 C CA  . THR A 1 519 ? 211.660 234.177 140.078 1.00 52.27  ? 519  THR D CA  1 
ATOM   4085 C C   . THR A 1 519 ? 210.196 233.765 140.137 1.00 52.27  ? 519  THR D C   1 
ATOM   4086 O O   . THR A 1 519 ? 209.377 234.441 140.769 1.00 52.27  ? 519  THR D O   1 
ATOM   4087 C CB  . THR A 1 519 ? 211.953 234.939 138.786 1.00 52.27  ? 519  THR D CB  1 
ATOM   4088 O OG1 . THR A 1 519 ? 213.293 235.447 138.822 1.00 52.27  ? 519  THR D OG1 1 
ATOM   4089 C CG2 . THR A 1 519 ? 210.984 236.096 138.618 1.00 52.27  ? 519  THR D CG2 1 
ATOM   4090 N N   . LEU A 1 520 ? 209.845 232.657 139.484 1.00 53.40  ? 520  LEU D N   1 
ATOM   4091 C CA  . LEU A 1 520 ? 208.477 232.158 139.617 1.00 53.40  ? 520  LEU D CA  1 
ATOM   4092 C C   . LEU A 1 520 ? 208.206 231.658 141.035 1.00 53.40  ? 520  LEU D C   1 
ATOM   4093 O O   . LEU A 1 520 ? 207.148 231.949 141.618 1.00 53.40  ? 520  LEU D O   1 
ATOM   4094 C CB  . LEU A 1 520 ? 208.217 231.052 138.596 1.00 53.40  ? 520  LEU D CB  1 
ATOM   4095 C CG  . LEU A 1 520 ? 208.306 231.455 137.123 1.00 53.40  ? 520  LEU D CG  1 
ATOM   4096 C CD1 . LEU A 1 520 ? 207.843 230.317 136.230 1.00 53.40  ? 520  LEU D CD1 1 
ATOM   4097 C CD2 . LEU A 1 520 ? 207.497 232.714 136.859 1.00 53.40  ? 520  LEU D CD2 1 
ATOM   4098 N N   . TYR A 1 521 ? 209.161 230.920 141.609 1.00 52.83  ? 521  TYR D N   1 
ATOM   4099 C CA  . TYR A 1 521 ? 208.946 230.276 142.900 1.00 52.83  ? 521  TYR D CA  1 
ATOM   4100 C C   . TYR A 1 521 ? 208.808 231.295 144.023 1.00 52.83  ? 521  TYR D C   1 
ATOM   4101 O O   . TYR A 1 521 ? 208.028 231.085 144.956 1.00 52.83  ? 521  TYR D O   1 
ATOM   4102 C CB  . TYR A 1 521 ? 210.088 229.306 143.204 1.00 52.83  ? 521  TYR D CB  1 
ATOM   4103 C CG  . TYR A 1 521 ? 210.151 228.106 142.287 1.00 52.83  ? 521  TYR D CG  1 
ATOM   4104 C CD1 . TYR A 1 521 ? 209.042 227.704 141.556 1.00 52.83  ? 521  TYR D CD1 1 
ATOM   4105 C CD2 . TYR A 1 521 ? 211.322 227.372 142.156 1.00 52.83  ? 521  TYR D CD2 1 
ATOM   4106 C CE1 . TYR A 1 521 ? 209.098 226.607 140.718 1.00 52.83  ? 521  TYR D CE1 1 
ATOM   4107 C CE2 . TYR A 1 521 ? 211.388 226.274 141.321 1.00 52.83  ? 521  TYR D CE2 1 
ATOM   4108 C CZ  . TYR A 1 521 ? 210.273 225.896 140.604 1.00 52.83  ? 521  TYR D CZ  1 
ATOM   4109 O OH  . TYR A 1 521 ? 210.335 224.803 139.772 1.00 52.83  ? 521  TYR D OH  1 
ATOM   4110 N N   . GLN A 1 522 ? 209.562 232.396 143.964 1.00 52.41  ? 522  GLN D N   1 
ATOM   4111 C CA  . GLN A 1 522 ? 209.485 233.382 145.037 1.00 52.41  ? 522  GLN D CA  1 
ATOM   4112 C C   . GLN A 1 522 ? 208.100 234.012 145.102 1.00 52.41  ? 522  GLN D C   1 
ATOM   4113 O O   . GLN A 1 522 ? 207.531 234.163 146.188 1.00 52.41  ? 522  GLN D O   1 
ATOM   4114 C CB  . GLN A 1 522 ? 210.566 234.453 144.866 1.00 52.41  ? 522  GLN D CB  1 
ATOM   4115 C CG  . GLN A 1 522 ? 210.520 235.214 143.552 1.00 52.41  ? 522  GLN D CG  1 
ATOM   4116 C CD  . GLN A 1 522 ? 211.376 236.463 143.567 1.00 52.41  ? 522  GLN D CD  1 
ATOM   4117 O OE1 . GLN A 1 522 ? 211.873 236.902 142.530 1.00 52.41  ? 522  GLN D OE1 1 
ATOM   4118 N NE2 . GLN A 1 522 ? 211.548 237.048 144.746 1.00 52.41  ? 522  GLN D NE2 1 
ATOM   4119 N N   . PHE A 1 523 ? 207.523 234.353 143.949 1.00 52.61  ? 523  PHE D N   1 
ATOM   4120 C CA  . PHE A 1 523 ? 206.193 234.948 143.962 1.00 52.61  ? 523  PHE D CA  1 
ATOM   4121 C C   . PHE A 1 523 ? 205.122 233.921 144.303 1.00 52.61  ? 523  PHE D C   1 
ATOM   4122 O O   . PHE A 1 523 ? 204.140 234.259 144.978 1.00 52.61  ? 523  PHE D O   1 
ATOM   4123 C CB  . PHE A 1 523 ? 205.903 235.621 142.622 1.00 52.61  ? 523  PHE D CB  1 
ATOM   4124 C CG  . PHE A 1 523 ? 206.707 236.868 142.394 1.00 52.61  ? 523  PHE D CG  1 
ATOM   4125 C CD1 . PHE A 1 523 ? 206.455 238.012 143.131 1.00 52.61  ? 523  PHE D CD1 1 
ATOM   4126 C CD2 . PHE A 1 523 ? 207.718 236.895 141.451 1.00 52.61  ? 523  PHE D CD2 1 
ATOM   4127 C CE1 . PHE A 1 523 ? 207.195 239.160 142.929 1.00 52.61  ? 523  PHE D CE1 1 
ATOM   4128 C CE2 . PHE A 1 523 ? 208.460 238.040 141.243 1.00 52.61  ? 523  PHE D CE2 1 
ATOM   4129 C CZ  . PHE A 1 523 ? 208.198 239.174 141.983 1.00 52.61  ? 523  PHE D CZ  1 
ATOM   4130 N N   . GLN A 1 524 ? 205.294 232.667 143.875 1.00 53.24  ? 524  GLN D N   1 
ATOM   4131 C CA  . GLN A 1 524 ? 204.358 231.627 144.299 1.00 53.24  ? 524  GLN D CA  1 
ATOM   4132 C C   . GLN A 1 524 ? 204.374 231.463 145.817 1.00 53.24  ? 524  GLN D C   1 
ATOM   4133 O O   . GLN A 1 524 ? 203.318 231.420 146.462 1.00 53.24  ? 524  GLN D O   1 
ATOM   4134 C CB  . GLN A 1 524 ? 204.687 230.307 143.604 1.00 53.24  ? 524  GLN D CB  1 
ATOM   4135 C CG  . GLN A 1 524 ? 204.432 230.327 142.108 1.00 53.24  ? 524  GLN D CG  1 
ATOM   4136 C CD  . GLN A 1 524 ? 204.835 229.035 141.432 1.00 53.24  ? 524  GLN D CD  1 
ATOM   4137 O OE1 . GLN A 1 524 ? 204.446 227.949 141.859 1.00 53.24  ? 524  GLN D OE1 1 
ATOM   4138 N NE2 . GLN A 1 524 ? 205.626 229.146 140.373 1.00 53.24  ? 524  GLN D NE2 1 
ATOM   4139 N N   . PHE A 1 525 ? 205.572 231.384 146.405 1.00 54.10  ? 525  PHE D N   1 
ATOM   4140 C CA  . PHE A 1 525 ? 205.689 231.255 147.854 1.00 54.10  ? 525  PHE D CA  1 
ATOM   4141 C C   . PHE A 1 525 ? 205.121 232.476 148.560 1.00 54.10  ? 525  PHE D C   1 
ATOM   4142 O O   . PHE A 1 525 ? 204.481 232.353 149.610 1.00 54.10  ? 525  PHE D O   1 
ATOM   4143 C CB  . PHE A 1 525 ? 207.152 231.057 148.262 1.00 54.10  ? 525  PHE D CB  1 
ATOM   4144 C CG  . PHE A 1 525 ? 207.803 229.839 147.667 1.00 54.10  ? 525  PHE D CG  1 
ATOM   4145 C CD1 . PHE A 1 525 ? 207.047 228.804 147.147 1.00 54.10  ? 525  PHE D CD1 1 
ATOM   4146 C CD2 . PHE A 1 525 ? 209.184 229.732 147.637 1.00 54.10  ? 525  PHE D CD2 1 
ATOM   4147 C CE1 . PHE A 1 525 ? 207.657 227.692 146.600 1.00 54.10  ? 525  PHE D CE1 1 
ATOM   4148 C CE2 . PHE A 1 525 ? 209.797 228.621 147.096 1.00 54.10  ? 525  PHE D CE2 1 
ATOM   4149 C CZ  . PHE A 1 525 ? 209.033 227.599 146.578 1.00 54.10  ? 525  PHE D CZ  1 
ATOM   4150 N N   . GLN A 1 526 ? 205.356 233.667 148.005 1.00 54.59  ? 526  GLN D N   1 
ATOM   4151 C CA  . GLN A 1 526 ? 204.850 234.887 148.621 1.00 54.59  ? 526  GLN D CA  1 
ATOM   4152 C C   . GLN A 1 526 ? 203.328 234.896 148.640 1.00 54.59  ? 526  GLN D C   1 
ATOM   4153 O O   . GLN A 1 526 ? 202.713 235.195 149.668 1.00 54.59  ? 526  GLN D O   1 
ATOM   4154 C CB  . GLN A 1 526 ? 205.391 236.111 147.881 1.00 54.59  ? 526  GLN D CB  1 
ATOM   4155 C CG  . GLN A 1 526 ? 204.967 237.444 148.481 1.00 54.59  ? 526  GLN D CG  1 
ATOM   4156 C CD  . GLN A 1 526 ? 205.582 237.700 149.844 1.00 54.59  ? 526  GLN D CD  1 
ATOM   4157 O OE1 . GLN A 1 526 ? 206.565 237.066 150.225 1.00 54.59  ? 526  GLN D OE1 1 
ATOM   4158 N NE2 . GLN A 1 526 ? 205.003 238.636 150.586 1.00 54.59  ? 526  GLN D NE2 1 
ATOM   4159 N N   . GLU A 1 527 ? 202.702 234.556 147.509 1.00 56.08  ? 527  GLU D N   1 
ATOM   4160 C CA  . GLU A 1 527 ? 201.244 234.514 147.470 1.00 56.08  ? 527  GLU D CA  1 
ATOM   4161 C C   . GLU A 1 527 ? 200.698 233.455 148.420 1.00 56.08  ? 527  GLU D C   1 
ATOM   4162 O O   . GLU A 1 527 ? 199.696 233.687 149.108 1.00 56.08  ? 527  GLU D O   1 
ATOM   4163 C CB  . GLU A 1 527 ? 200.752 234.254 146.047 1.00 56.08  ? 527  GLU D CB  1 
ATOM   4164 C CG  . GLU A 1 527 ? 199.257 234.489 145.878 1.00 56.08  ? 527  GLU D CG  1 
ATOM   4165 C CD  . GLU A 1 527 ? 198.709 233.903 144.595 1.00 56.08  ? 527  GLU D CD  1 
ATOM   4166 O OE1 . GLU A 1 527 ? 199.165 232.811 144.197 1.00 56.08  ? 527  GLU D OE1 1 
ATOM   4167 O OE2 . GLU A 1 527 ? 197.820 234.533 143.984 1.00 56.08  ? 527  GLU D OE2 1 
ATOM   4168 N N   . ALA A 1 528 ? 201.349 232.290 148.482 1.00 56.45  ? 528  ALA D N   1 
ATOM   4169 C CA  . ALA A 1 528 ? 200.874 231.229 149.365 1.00 56.45  ? 528  ALA D CA  1 
ATOM   4170 C C   . ALA A 1 528 ? 200.961 231.647 150.829 1.00 56.45  ? 528  ALA D C   1 
ATOM   4171 O O   . ALA A 1 528 ? 200.002 231.484 151.592 1.00 56.45  ? 528  ALA D O   1 
ATOM   4172 C CB  . ALA A 1 528 ? 201.672 229.949 149.120 1.00 56.45  ? 528  ALA D CB  1 
ATOM   4173 N N   . LEU A 1 529 ? 202.108 232.196 151.238 1.00 56.57  ? 529  LEU D N   1 
ATOM   4174 C CA  . LEU A 1 529 ? 202.281 232.602 152.628 1.00 56.57  ? 529  LEU D CA  1 
ATOM   4175 C C   . LEU A 1 529 ? 201.422 233.810 152.976 1.00 56.57  ? 529  LEU D C   1 
ATOM   4176 O O   . LEU A 1 529 ? 201.061 233.992 154.144 1.00 56.57  ? 529  LEU D O   1 
ATOM   4177 C CB  . LEU A 1 529 ? 203.754 232.896 152.912 1.00 56.57  ? 529  LEU D CB  1 
ATOM   4178 C CG  . LEU A 1 529 ? 204.718 231.717 152.764 1.00 56.57  ? 529  LEU D CG  1 
ATOM   4179 C CD1 . LEU A 1 529 ? 206.134 232.128 153.136 1.00 56.57  ? 529  LEU D CD1 1 
ATOM   4180 C CD2 . LEU A 1 529 ? 204.259 230.536 153.603 1.00 56.57  ? 529  LEU D CD2 1 
ATOM   4181 N N   . CYS A 1 530 ? 201.086 234.643 151.989 1.00 62.36  ? 530  CYS D N   1 
ATOM   4182 C CA  . CYS A 1 530 ? 200.203 235.772 152.252 1.00 62.36  ? 530  CYS D CA  1 
ATOM   4183 C C   . CYS A 1 530 ? 198.757 235.319 152.402 1.00 62.36  ? 530  CYS D C   1 
ATOM   4184 O O   . CYS A 1 530 ? 198.022 235.848 153.242 1.00 62.36  ? 530  CYS D O   1 
ATOM   4185 C CB  . CYS A 1 530 ? 200.329 236.808 151.136 1.00 62.36  ? 530  CYS D CB  1 
ATOM   4186 S SG  . CYS A 1 530 ? 199.514 238.369 151.509 1.00 62.36  ? 530  CYS D SG  1 
ATOM   4187 N N   . GLN A 1 531 ? 198.332 234.344 151.594 1.00 60.89  ? 531  GLN D N   1 
ATOM   4188 C CA  . GLN A 1 531 ? 196.997 233.780 151.762 1.00 60.89  ? 531  GLN D CA  1 
ATOM   4189 C C   . GLN A 1 531 ? 196.888 233.019 153.076 1.00 60.89  ? 531  GLN D C   1 
ATOM   4190 O O   . GLN A 1 531 ? 195.833 233.030 153.722 1.00 60.89  ? 531  GLN D O   1 
ATOM   4191 C CB  . GLN A 1 531 ? 196.660 232.872 150.580 1.00 60.89  ? 531  GLN D CB  1 
ATOM   4192 C CG  . GLN A 1 531 ? 195.274 232.253 150.643 1.00 60.89  ? 531  GLN D CG  1 
ATOM   4193 C CD  . GLN A 1 531 ? 194.964 231.396 149.432 1.00 60.89  ? 531  GLN D CD  1 
ATOM   4194 O OE1 . GLN A 1 531 ? 193.913 230.759 149.360 1.00 60.89  ? 531  GLN D OE1 1 
ATOM   4195 N NE2 . GLN A 1 531 ? 195.880 231.377 148.471 1.00 60.89  ? 531  GLN D NE2 1 
ATOM   4196 N N   . ALA A 1 532 ? 197.969 232.355 153.492 1.00 58.96  ? 532  ALA D N   1 
ATOM   4197 C CA  . ALA A 1 532 ? 197.968 231.661 154.773 1.00 58.96  ? 532  ALA D CA  1 
ATOM   4198 C C   . ALA A 1 532 ? 198.047 232.621 155.953 1.00 58.96  ? 532  ALA D C   1 
ATOM   4199 O O   . ALA A 1 532 ? 197.749 232.219 157.083 1.00 58.96  ? 532  ALA D O   1 
ATOM   4200 C CB  . ALA A 1 532 ? 199.127 230.665 154.834 1.00 58.96  ? 532  ALA D CB  1 
ATOM   4201 N N   . ALA A 1 533 ? 198.438 233.871 155.720 1.00 60.67  ? 533  ALA D N   1 
ATOM   4202 C CA  . ALA A 1 533 ? 198.551 234.866 156.777 1.00 60.67  ? 533  ALA D CA  1 
ATOM   4203 C C   . ALA A 1 533 ? 197.277 235.677 156.973 1.00 60.67  ? 533  ALA D C   1 
ATOM   4204 O O   . ALA A 1 533 ? 197.259 236.572 157.825 1.00 60.67  ? 533  ALA D O   1 
ATOM   4205 C CB  . ALA A 1 533 ? 199.720 235.812 156.488 1.00 60.67  ? 533  ALA D CB  1 
ATOM   4206 N N   . LYS A 1 534 ? 196.222 235.389 156.207 1.00 63.02  ? 534  LYS D N   1 
ATOM   4207 C CA  . LYS A 1 534 ? 194.945 236.100 156.304 1.00 63.02  ? 534  LYS D CA  1 
ATOM   4208 C C   . LYS A 1 534 ? 195.133 237.602 156.087 1.00 63.02  ? 534  LYS D C   1 
ATOM   4209 O O   . LYS A 1 534 ? 194.629 238.434 156.844 1.00 63.02  ? 534  LYS D O   1 
ATOM   4210 C CB  . LYS A 1 534 ? 194.250 235.821 157.641 1.00 63.02  ? 534  LYS D CB  1 
ATOM   4211 C CG  . LYS A 1 534 ? 193.647 234.428 157.770 1.00 63.02  ? 534  LYS D CG  1 
ATOM   4212 C CD  . LYS A 1 534 ? 194.686 233.391 158.168 1.00 63.02  ? 534  LYS D CD  1 
ATOM   4213 C CE  . LYS A 1 534 ? 195.318 233.734 159.507 1.00 63.02  ? 534  LYS D CE  1 
ATOM   4214 N NZ  . LYS A 1 534 ? 194.305 233.811 160.595 1.00 63.02  ? 534  LYS D NZ  1 
ATOM   4215 N N   . HIS A 1 535 ? 195.872 237.944 155.037 1.00 61.07  ? 535  HIS D N   1 
ATOM   4216 C CA  . HIS A 1 535 ? 196.155 239.328 154.682 1.00 61.07  ? 535  HIS D CA  1 
ATOM   4217 C C   . HIS A 1 535 ? 195.328 239.719 153.466 1.00 61.07  ? 535  HIS D C   1 
ATOM   4218 O O   . HIS A 1 535 ? 195.257 238.965 152.490 1.00 61.07  ? 535  HIS D O   1 
ATOM   4219 C CB  . HIS A 1 535 ? 197.645 239.524 154.399 1.00 61.07  ? 535  HIS D CB  1 
ATOM   4220 C CG  . HIS A 1 535 ? 197.984 240.871 153.840 1.00 61.07  ? 535  HIS D CG  1 
ATOM   4221 N ND1 . HIS A 1 535 ? 198.119 241.102 152.488 1.00 61.07  ? 535  HIS D ND1 1 
ATOM   4222 C CD2 . HIS A 1 535 ? 198.221 242.056 154.450 1.00 61.07  ? 535  HIS D CD2 1 
ATOM   4223 C CE1 . HIS A 1 535 ? 198.422 242.373 152.289 1.00 61.07  ? 535  HIS D CE1 1 
ATOM   4224 N NE2 . HIS A 1 535 ? 198.490 242.973 153.464 1.00 61.07  ? 535  HIS D NE2 1 
ATOM   4225 N N   . GLU A 1 536 ? 194.710 240.893 153.527 1.00 63.23  ? 536  GLU D N   1 
ATOM   4226 C CA  . GLU A 1 536 ? 193.881 241.405 152.448 1.00 63.23  ? 536  GLU D CA  1 
ATOM   4227 C C   . GLU A 1 536 ? 194.536 242.625 151.814 1.00 63.23  ? 536  GLU D C   1 
ATOM   4228 O O   . GLU A 1 536 ? 195.351 243.315 152.432 1.00 63.23  ? 536  GLU D O   1 
ATOM   4229 C CB  . GLU A 1 536 ? 192.477 241.765 152.950 1.00 63.23  ? 536  GLU D CB  1 
ATOM   4230 C CG  . GLU A 1 536 ? 192.434 242.908 153.956 1.00 63.23  ? 536  GLU D CG  1 
ATOM   4231 C CD  . GLU A 1 536 ? 192.838 242.480 155.354 1.00 63.23  ? 536  GLU D CD  1 
ATOM   4232 O OE1 . GLU A 1 536 ? 192.976 241.262 155.589 1.00 63.23  ? 536  GLU D OE1 1 
ATOM   4233 O OE2 . GLU A 1 536 ? 193.018 243.364 156.218 1.00 63.23  ? 536  GLU D OE2 1 
ATOM   4234 N N   . GLY A 1 537 ? 194.167 242.881 150.563 1.00 60.16  ? 537  GLY D N   1 
ATOM   4235 C CA  . GLY A 1 537 ? 194.720 243.985 149.817 1.00 60.16  ? 537  GLY D CA  1 
ATOM   4236 C C   . GLY A 1 537 ? 195.697 243.520 148.758 1.00 60.16  ? 537  GLY D C   1 
ATOM   4237 O O   . GLY A 1 537 ? 195.649 242.375 148.296 1.00 60.16  ? 537  GLY D O   1 
ATOM   4238 N N   . PRO A 1 538 ? 196.603 244.403 148.349 1.00 57.42  ? 538  PRO D N   1 
ATOM   4239 C CA  . PRO A 1 538 ? 197.599 244.024 147.343 1.00 57.42  ? 538  PRO D CA  1 
ATOM   4240 C C   . PRO A 1 538 ? 198.618 243.047 147.908 1.00 57.42  ? 538  PRO D C   1 
ATOM   4241 O O   . PRO A 1 538 ? 198.819 242.936 149.120 1.00 57.42  ? 538  PRO D O   1 
ATOM   4242 C CB  . PRO A 1 538 ? 198.253 245.358 146.971 1.00 57.42  ? 538  PRO D CB  1 
ATOM   4243 C CG  . PRO A 1 538 ? 198.066 246.210 148.179 1.00 57.42  ? 538  PRO D CG  1 
ATOM   4244 C CD  . PRO A 1 538 ? 196.741 245.809 148.765 1.00 57.42  ? 538  PRO D CD  1 
ATOM   4245 N N   . LEU A 1 539 ? 199.271 242.327 146.995 1.00 55.51  ? 539  LEU D N   1 
ATOM   4246 C CA  . LEU A 1 539 ? 200.242 241.316 147.396 1.00 55.51  ? 539  LEU D CA  1 
ATOM   4247 C C   . LEU A 1 539 ? 201.588 241.924 147.771 1.00 55.51  ? 539  LEU D C   1 
ATOM   4248 O O   . LEU A 1 539 ? 202.286 241.384 148.636 1.00 55.51  ? 539  LEU D O   1 
ATOM   4249 C CB  . LEU A 1 539 ? 200.422 240.291 146.274 1.00 55.51  ? 539  LEU D CB  1 
ATOM   4250 C CG  . LEU A 1 539 ? 201.379 239.128 146.538 1.00 55.51  ? 539  LEU D CG  1 
ATOM   4251 C CD1 . LEU A 1 539 ? 200.941 238.341 147.763 1.00 55.51  ? 539  LEU D CD1 1 
ATOM   4252 C CD2 . LEU A 1 539 ? 201.472 238.222 145.321 1.00 55.51  ? 539  LEU D CD2 1 
ATOM   4253 N N   . HIS A 1 540 ? 201.966 243.041 147.145 1.00 56.57  ? 540  HIS D N   1 
ATOM   4254 C CA  . HIS A 1 540 ? 203.268 243.639 147.416 1.00 56.57  ? 540  HIS D CA  1 
ATOM   4255 C C   . HIS A 1 540 ? 203.330 244.314 148.780 1.00 56.57  ? 540  HIS D C   1 
ATOM   4256 O O   . HIS A 1 540 ? 204.431 244.575 149.277 1.00 56.57  ? 540  HIS D O   1 
ATOM   4257 C CB  . HIS A 1 540 ? 203.622 244.643 146.318 1.00 56.57  ? 540  HIS D CB  1 
ATOM   4258 C CG  . HIS A 1 540 ? 202.589 245.706 146.114 1.00 56.57  ? 540  HIS D CG  1 
ATOM   4259 N ND1 . HIS A 1 540 ? 202.496 246.818 146.923 1.00 56.57  ? 540  HIS D ND1 1 
ATOM   4260 C CD2 . HIS A 1 540 ? 201.603 245.827 145.194 1.00 56.57  ? 540  HIS D CD2 1 
ATOM   4261 C CE1 . HIS A 1 540 ? 201.498 247.577 146.510 1.00 56.57  ? 540  HIS D CE1 1 
ATOM   4262 N NE2 . HIS A 1 540 ? 200.940 246.999 145.462 1.00 56.57  ? 540  HIS D NE2 1 
ATOM   4263 N N   . LYS A 1 541 ? 202.183 244.603 149.396 1.00 58.06  ? 541  LYS D N   1 
ATOM   4264 C CA  . LYS A 1 541 ? 202.131 245.201 150.725 1.00 58.06  ? 541  LYS D CA  1 
ATOM   4265 C C   . LYS A 1 541 ? 201.879 244.164 151.814 1.00 58.06  ? 541  LYS D C   1 
ATOM   4266 O O   . LYS A 1 541 ? 201.354 244.500 152.881 1.00 58.06  ? 541  LYS D O   1 
ATOM   4267 C CB  . LYS A 1 541 ? 201.060 246.291 150.776 1.00 58.06  ? 541  LYS D CB  1 
ATOM   4268 C CG  . LYS A 1 541 ? 201.394 247.532 149.968 1.00 58.06  ? 541  LYS D CG  1 
ATOM   4269 C CD  . LYS A 1 541 ? 200.252 248.534 149.997 1.00 58.06  ? 541  LYS D CD  1 
ATOM   4270 C CE  . LYS A 1 541 ? 199.929 248.965 151.417 1.00 58.06  ? 541  LYS D CE  1 
ATOM   4271 N NZ  . LYS A 1 541 ? 198.813 249.950 151.455 1.00 58.06  ? 541  LYS D NZ  1 
ATOM   4272 N N   . CYS A 1 542 ? 202.244 242.911 151.568 1.00 61.48  ? 542  CYS D N   1 
ATOM   4273 C CA  . CYS A 1 542 ? 201.969 241.824 152.495 1.00 61.48  ? 542  CYS D CA  1 
ATOM   4274 C C   . CYS A 1 542 ? 203.170 241.580 153.399 1.00 61.48  ? 542  CYS D C   1 
ATOM   4275 O O   . CYS A 1 542 ? 204.317 241.576 152.943 1.00 61.48  ? 542  CYS D O   1 
ATOM   4276 C CB  . CYS A 1 542 ? 201.611 240.542 151.742 1.00 61.48  ? 542  CYS D CB  1 
ATOM   4277 S SG  . CYS A 1 542 ? 200.803 239.301 152.771 1.00 61.48  ? 542  CYS D SG  1 
ATOM   4278 N N   . ASP A 1 543 ? 202.894 241.375 154.684 1.00 63.49  ? 543  ASP D N   1 
ATOM   4279 C CA  . ASP A 1 543 ? 203.919 241.121 155.686 1.00 63.49  ? 543  ASP D CA  1 
ATOM   4280 C C   . ASP A 1 543 ? 203.540 239.873 156.468 1.00 63.49  ? 543  ASP D C   1 
ATOM   4281 O O   . ASP A 1 543 ? 202.401 239.748 156.928 1.00 63.49  ? 543  ASP D O   1 
ATOM   4282 C CB  . ASP A 1 543 ? 204.078 242.321 156.627 1.00 63.49  ? 543  ASP D CB  1 
ATOM   4283 C CG  . ASP A 1 543 ? 205.105 242.079 157.712 1.00 63.49  ? 543  ASP D CG  1 
ATOM   4284 O OD1 . ASP A 1 543 ? 206.294 241.896 157.378 1.00 63.49  ? 543  ASP D OD1 1 
ATOM   4285 O OD2 . ASP A 1 543 ? 204.723 242.079 158.900 1.00 63.49  ? 543  ASP D OD2 1 
ATOM   4286 N N   . ILE A 1 544 ? 204.493 238.955 156.616 1.00 60.74  ? 544  ILE D N   1 
ATOM   4287 C CA  . ILE A 1 544 ? 204.241 237.676 157.270 1.00 60.74  ? 544  ILE D CA  1 
ATOM   4288 C C   . ILE A 1 544 ? 205.074 237.576 158.540 1.00 60.74  ? 544  ILE D C   1 
ATOM   4289 O O   . ILE A 1 544 ? 205.503 236.484 158.930 1.00 60.74  ? 544  ILE D O   1 
ATOM   4290 C CB  . ILE A 1 544 ? 204.536 236.500 156.322 1.00 60.74  ? 544  ILE D CB  1 
ATOM   4291 C CG1 . ILE A 1 544 ? 205.955 236.607 155.761 1.00 60.74  ? 544  ILE D CG1 1 
ATOM   4292 C CG2 . ILE A 1 544 ? 203.517 236.457 155.194 1.00 60.74  ? 544  ILE D CG2 1 
ATOM   4293 C CD1 . ILE A 1 544 ? 206.332 235.476 154.833 1.00 60.74  ? 544  ILE D CD1 1 
ATOM   4294 N N   . SER A 1 545 ? 205.307 238.716 159.194 1.00 62.98  ? 545  SER D N   1 
ATOM   4295 C CA  . SER A 1 545 ? 206.161 238.731 160.378 1.00 62.98  ? 545  SER D CA  1 
ATOM   4296 C C   . SER A 1 545 ? 205.529 237.960 161.531 1.00 62.98  ? 545  SER D C   1 
ATOM   4297 O O   . SER A 1 545 ? 206.156 237.066 162.109 1.00 62.98  ? 545  SER D O   1 
ATOM   4298 C CB  . SER A 1 545 ? 206.456 240.173 160.791 1.00 62.98  ? 545  SER D CB  1 
ATOM   4299 O OG  . SER A 1 545 ? 207.288 240.215 161.937 1.00 62.98  ? 545  SER D OG  1 
ATOM   4300 N N   . ASN A 1 546 ? 204.287 238.289 161.880 1.00 65.89  ? 546  ASN D N   1 
ATOM   4301 C CA  . ASN A 1 546 ? 203.601 237.687 163.022 1.00 65.89  ? 546  ASN D CA  1 
ATOM   4302 C C   . ASN A 1 546 ? 202.626 236.595 162.601 1.00 65.89  ? 546  ASN D C   1 
ATOM   4303 O O   . ASN A 1 546 ? 201.561 236.439 163.206 1.00 65.89  ? 546  ASN D O   1 
ATOM   4304 C CB  . ASN A 1 546 ? 202.882 238.761 163.832 1.00 65.89  ? 546  ASN D CB  1 
ATOM   4305 C CG  . ASN A 1 546 ? 203.839 239.705 164.531 1.00 65.89  ? 546  ASN D CG  1 
ATOM   4306 O OD1 . ASN A 1 546 ? 205.027 239.752 164.214 1.00 65.89  ? 546  ASN D OD1 1 
ATOM   4307 N ND2 . ASN A 1 546 ? 203.323 240.465 165.489 1.00 65.89  ? 546  ASN D ND2 1 
ATOM   4308 N N   . SER A 1 547 ? 202.958 235.825 161.570 1.00 62.65  ? 547  SER D N   1 
ATOM   4309 C CA  . SER A 1 547 ? 202.087 234.771 161.055 1.00 62.65  ? 547  SER D CA  1 
ATOM   4310 C C   . SER A 1 547 ? 202.766 233.424 161.287 1.00 62.65  ? 547  SER D C   1 
ATOM   4311 O O   . SER A 1 547 ? 203.647 233.022 160.522 1.00 62.65  ? 547  SER D O   1 
ATOM   4312 C CB  . SER A 1 547 ? 201.781 234.995 159.577 1.00 62.65  ? 547  SER D CB  1 
ATOM   4313 O OG  . SER A 1 547 ? 201.156 236.250 159.375 1.00 62.65  ? 547  SER D OG  1 
ATOM   4314 N N   . THR A 1 548 ? 202.348 232.727 162.346 1.00 59.24  ? 548  THR D N   1 
ATOM   4315 C CA  . THR A 1 548 ? 202.911 231.414 162.640 1.00 59.24  ? 548  THR D CA  1 
ATOM   4316 C C   . THR A 1 548 ? 202.382 230.340 161.698 1.00 59.24  ? 548  THR D C   1 
ATOM   4317 O O   . THR A 1 548 ? 203.066 229.336 161.466 1.00 59.24  ? 548  THR D O   1 
ATOM   4318 C CB  . THR A 1 548 ? 202.622 231.028 164.093 1.00 59.24  ? 548  THR D CB  1 
ATOM   4319 O OG1 . THR A 1 548 ? 203.074 229.690 164.333 1.00 59.24  ? 548  THR D OG1 1 
ATOM   4320 C CG2 . THR A 1 548 ? 201.132 231.118 164.387 1.00 59.24  ? 548  THR D CG2 1 
ATOM   4321 N N   . GLU A 1 549 ? 201.182 230.531 161.146 1.00 60.99  ? 549  GLU D N   1 
ATOM   4322 C CA  . GLU A 1 549 ? 200.641 229.566 160.194 1.00 60.99  ? 549  GLU D CA  1 
ATOM   4323 C C   . GLU A 1 549 ? 201.488 229.518 158.929 1.00 60.99  ? 549  GLU D C   1 
ATOM   4324 O O   . GLU A 1 549 ? 201.836 228.437 158.440 1.00 60.99  ? 549  GLU D O   1 
ATOM   4325 C CB  . GLU A 1 549 ? 199.191 229.915 159.861 1.00 60.99  ? 549  GLU D CB  1 
ATOM   4326 C CG  . GLU A 1 549 ? 198.264 229.934 161.064 1.00 60.99  ? 549  GLU D CG  1 
ATOM   4327 C CD  . GLU A 1 549 ? 196.837 230.283 160.692 1.00 60.99  ? 549  GLU D CD  1 
ATOM   4328 O OE1 . GLU A 1 549 ? 196.570 230.502 159.492 1.00 60.99  ? 549  GLU D OE1 1 
ATOM   4329 O OE2 . GLU A 1 549 ? 195.981 230.339 161.601 1.00 60.99  ? 549  GLU D OE2 1 
ATOM   4330 N N   . ALA A 1 550 ? 201.832 230.688 158.385 1.00 57.40  ? 550  ALA D N   1 
ATOM   4331 C CA  . ALA A 1 550 ? 202.707 230.731 157.219 1.00 57.40  ? 550  ALA D CA  1 
ATOM   4332 C C   . ALA A 1 550 ? 204.092 230.197 157.555 1.00 57.40  ? 550  ALA D C   1 
ATOM   4333 O O   . ALA A 1 550 ? 204.732 229.541 156.724 1.00 57.40  ? 550  ALA D O   1 
ATOM   4334 C CB  . ALA A 1 550 ? 202.796 232.159 156.681 1.00 57.40  ? 550  ALA D CB  1 
ATOM   4335 N N   . GLY A 1 551 ? 204.567 230.457 158.774 1.00 56.24  ? 551  GLY D N   1 
ATOM   4336 C CA  . GLY A 1 551 ? 205.853 229.917 159.185 1.00 56.24  ? 551  GLY D CA  1 
ATOM   4337 C C   . GLY A 1 551 ? 205.868 228.401 159.186 1.00 56.24  ? 551  GLY D C   1 
ATOM   4338 O O   . GLY A 1 551 ? 206.807 227.776 158.690 1.00 56.24  ? 551  GLY D O   1 
ATOM   4339 N N   . GLN A 1 552 ? 204.818 227.788 159.737 1.00 57.30  ? 552  GLN D N   1 
ATOM   4340 C CA  . GLN A 1 552 ? 204.732 226.331 159.739 1.00 57.30  ? 552  GLN D CA  1 
ATOM   4341 C C   . GLN A 1 552 ? 204.556 225.786 158.326 1.00 57.30  ? 552  GLN D C   1 
ATOM   4342 O O   . GLN A 1 552 ? 205.141 224.752 157.975 1.00 57.30  ? 552  GLN D O   1 
ATOM   4343 C CB  . GLN A 1 552 ? 203.584 225.875 160.639 1.00 57.30  ? 552  GLN D CB  1 
ATOM   4344 C CG  . GLN A 1 552 ? 203.430 224.367 160.733 1.00 57.30  ? 552  GLN D CG  1 
ATOM   4345 C CD  . GLN A 1 552 ? 202.262 223.955 161.607 1.00 57.30  ? 552  GLN D CD  1 
ATOM   4346 O OE1 . GLN A 1 552 ? 202.009 222.766 161.804 1.00 57.30  ? 552  GLN D OE1 1 
ATOM   4347 N NE2 . GLN A 1 552 ? 201.544 224.938 162.137 1.00 57.30  ? 552  GLN D NE2 1 
ATOM   4348 N N   . LYS A 1 553 ? 203.760 226.470 157.500 1.00 55.89  ? 553  LYS D N   1 
ATOM   4349 C CA  . LYS A 1 553 ? 203.552 226.018 156.129 1.00 55.89  ? 553  LYS D CA  1 
ATOM   4350 C C   . LYS A 1 553 ? 204.837 226.087 155.314 1.00 55.89  ? 553  LYS D C   1 
ATOM   4351 O O   . LYS A 1 553 ? 205.040 225.270 154.408 1.00 55.89  ? 553  LYS D O   1 
ATOM   4352 C CB  . LYS A 1 553 ? 202.453 226.851 155.469 1.00 55.89  ? 553  LYS D CB  1 
ATOM   4353 C CG  . LYS A 1 553 ? 201.790 226.190 154.274 1.00 55.89  ? 553  LYS D CG  1 
ATOM   4354 C CD  . LYS A 1 553 ? 200.618 227.021 153.777 1.00 55.89  ? 553  LYS D CD  1 
ATOM   4355 C CE  . LYS A 1 553 ? 199.789 226.262 152.756 1.00 55.89  ? 553  LYS D CE  1 
ATOM   4356 N NZ  . LYS A 1 553 ? 200.591 225.866 151.568 1.00 55.89  ? 553  LYS D NZ  1 
ATOM   4357 N N   . LEU A 1 554 ? 205.713 227.045 155.621 1.00 54.44  ? 554  LEU D N   1 
ATOM   4358 C CA  . LEU A 1 554 ? 206.994 227.126 154.930 1.00 54.44  ? 554  LEU D CA  1 
ATOM   4359 C C   . LEU A 1 554 ? 208.000 226.136 155.505 1.00 54.44  ? 554  LEU D C   1 
ATOM   4360 O O   . LEU A 1 554 ? 208.818 225.578 154.765 1.00 54.44  ? 554  LEU D O   1 
ATOM   4361 C CB  . LEU A 1 554 ? 207.542 228.551 155.007 1.00 54.44  ? 554  LEU D CB  1 
ATOM   4362 C CG  . LEU A 1 554 ? 208.825 228.831 154.224 1.00 54.44  ? 554  LEU D CG  1 
ATOM   4363 C CD1 . LEU A 1 554 ? 208.612 228.578 152.741 1.00 54.44  ? 554  LEU D CD1 1 
ATOM   4364 C CD2 . LEU A 1 554 ? 209.297 230.253 154.464 1.00 54.44  ? 554  LEU D CD2 1 
ATOM   4365 N N   . PHE A 1 555 ? 207.954 225.905 156.820 1.00 53.27  ? 555  PHE D N   1 
ATOM   4366 C CA  . PHE A 1 555 ? 208.849 224.931 157.434 1.00 53.27  ? 555  PHE D CA  1 
ATOM   4367 C C   . PHE A 1 555 ? 208.529 223.515 156.976 1.00 53.27  ? 555  PHE D C   1 
ATOM   4368 O O   . PHE A 1 555 ? 209.426 222.666 156.921 1.00 53.27  ? 555  PHE D O   1 
ATOM   4369 C CB  . PHE A 1 555 ? 208.768 225.032 158.957 1.00 53.27  ? 555  PHE D CB  1 
ATOM   4370 C CG  . PHE A 1 555 ? 209.748 224.152 159.679 1.00 53.27  ? 555  PHE D CG  1 
ATOM   4371 C CD1 . PHE A 1 555 ? 211.052 224.570 159.885 1.00 53.27  ? 555  PHE D CD1 1 
ATOM   4372 C CD2 . PHE A 1 555 ? 209.364 222.910 160.158 1.00 53.27  ? 555  PHE D CD2 1 
ATOM   4373 C CE1 . PHE A 1 555 ? 211.956 223.764 160.550 1.00 53.27  ? 555  PHE D CE1 1 
ATOM   4374 C CE2 . PHE A 1 555 ? 210.264 222.100 160.824 1.00 53.27  ? 555  PHE D CE2 1 
ATOM   4375 C CZ  . PHE A 1 555 ? 211.561 222.528 161.020 1.00 53.27  ? 555  PHE D CZ  1 
ATOM   4376 N N   . ASN A 1 556 ? 207.263 223.241 156.649 1.00 56.51  ? 556  ASN D N   1 
ATOM   4377 C CA  . ASN A 1 556 ? 206.911 221.942 156.089 1.00 56.51  ? 556  ASN D CA  1 
ATOM   4378 C C   . ASN A 1 556 ? 207.593 221.692 154.750 1.00 56.51  ? 556  ASN D C   1 
ATOM   4379 O O   . ASN A 1 556 ? 207.786 220.531 154.372 1.00 56.51  ? 556  ASN D O   1 
ATOM   4380 C CB  . ASN A 1 556 ? 205.394 221.826 155.930 1.00 56.51  ? 556  ASN D CB  1 
ATOM   4381 C CG  . ASN A 1 556 ? 204.671 221.780 157.261 1.00 56.51  ? 556  ASN D CG  1 
ATOM   4382 O OD1 . ASN A 1 556 ? 205.202 221.278 158.251 1.00 56.51  ? 556  ASN D OD1 1 
ATOM   4383 N ND2 . ASN A 1 556 ? 203.452 222.304 157.290 1.00 56.51  ? 556  ASN D ND2 1 
ATOM   4384 N N   . MET A 1 557 ? 207.963 222.750 154.029 1.00 55.48  ? 557  MET D N   1 
ATOM   4385 C CA  . MET A 1 557 ? 208.680 222.614 152.768 1.00 55.48  ? 557  MET D CA  1 
ATOM   4386 C C   . MET A 1 557 ? 210.191 222.673 152.962 1.00 55.48  ? 557  MET D C   1 
ATOM   4387 O O   . MET A 1 557 ? 210.931 221.957 152.279 1.00 55.48  ? 557  MET D O   1 
ATOM   4388 C CB  . MET A 1 557 ? 208.230 223.703 151.790 1.00 55.48  ? 557  MET D CB  1 
ATOM   4389 C CG  . MET A 1 557 ? 208.768 223.552 150.374 1.00 55.48  ? 557  MET D CG  1 
ATOM   4390 S SD  . MET A 1 557 ? 210.372 224.334 150.111 1.00 55.48  ? 557  MET D SD  1 
ATOM   4391 C CE  . MET A 1 557 ? 209.955 226.055 150.373 1.00 55.48  ? 557  MET D CE  1 
ATOM   4392 N N   . LEU A 1 558 ? 210.663 223.515 153.884 1.00 52.61  ? 558  LEU D N   1 
ATOM   4393 C CA  . LEU A 1 558 ? 212.094 223.610 154.146 1.00 52.61  ? 558  LEU D CA  1 
ATOM   4394 C C   . LEU A 1 558 ? 212.646 222.357 154.812 1.00 52.61  ? 558  LEU D C   1 
ATOM   4395 O O   . LEU A 1 558 ? 213.849 222.095 154.712 1.00 52.61  ? 558  LEU D O   1 
ATOM   4396 C CB  . LEU A 1 558 ? 212.393 224.830 155.019 1.00 52.61  ? 558  LEU D CB  1 
ATOM   4397 C CG  . LEU A 1 558 ? 211.964 226.200 154.489 1.00 52.61  ? 558  LEU D CG  1 
ATOM   4398 C CD1 . LEU A 1 558 ? 212.428 227.305 155.425 1.00 52.61  ? 558  LEU D CD1 1 
ATOM   4399 C CD2 . LEU A 1 558 ? 212.493 226.424 153.085 1.00 52.61  ? 558  LEU D CD2 1 
ATOM   4400 N N   . ARG A 1 559 ? 211.798 221.581 155.488 1.00 54.50  ? 559  ARG D N   1 
ATOM   4401 C CA  . ARG A 1 559 ? 212.256 220.373 156.162 1.00 54.50  ? 559  ARG D CA  1 
ATOM   4402 C C   . ARG A 1 559 ? 212.503 219.229 155.186 1.00 54.50  ? 559  ARG D C   1 
ATOM   4403 O O   . ARG A 1 559 ? 213.396 218.406 155.417 1.00 54.50  ? 559  ARG D O   1 
ATOM   4404 C CB  . ARG A 1 559 ? 211.236 219.952 157.222 1.00 54.50  ? 559  ARG D CB  1 
ATOM   4405 C CG  . ARG A 1 559 ? 211.582 218.676 157.968 1.00 54.50  ? 559  ARG D CG  1 
ATOM   4406 C CD  . ARG A 1 559 ? 210.449 218.263 158.889 1.00 54.50  ? 559  ARG D CD  1 
ATOM   4407 N NE  . ARG A 1 559 ? 209.173 218.204 158.183 1.00 54.50  ? 559  ARG D NE  1 
ATOM   4408 C CZ  . ARG A 1 559 ? 208.738 217.142 157.514 1.00 54.50  ? 559  ARG D CZ  1 
ATOM   4409 N NH1 . ARG A 1 559 ? 207.563 217.180 156.900 1.00 54.50  ? 559  ARG D NH1 1 
ATOM   4410 N NH2 . ARG A 1 559 ? 209.476 216.042 157.458 1.00 54.50  ? 559  ARG D NH2 1 
ATOM   4411 N N   . LEU A 1 560 ? 211.734 219.166 154.096 1.00 54.04  ? 560  LEU D N   1 
ATOM   4412 C CA  . LEU A 1 560 ? 211.882 218.068 153.145 1.00 54.04  ? 560  LEU D CA  1 
ATOM   4413 C C   . LEU A 1 560 ? 213.257 218.081 152.490 1.00 54.04  ? 560  LEU D C   1 
ATOM   4414 O O   . LEU A 1 560 ? 213.857 217.022 152.271 1.00 54.04  ? 560  LEU D O   1 
ATOM   4415 C CB  . LEU A 1 560 ? 210.783 218.142 152.085 1.00 54.04  ? 560  LEU D CB  1 
ATOM   4416 C CG  . LEU A 1 560 ? 209.344 218.085 152.599 1.00 54.04  ? 560  LEU D CG  1 
ATOM   4417 C CD1 . LEU A 1 560 ? 208.360 218.143 151.443 1.00 54.04  ? 560  LEU D CD1 1 
ATOM   4418 C CD2 . LEU A 1 560 ? 209.122 216.835 153.436 1.00 54.04  ? 560  LEU D CD2 1 
ATOM   4419 N N   . GLY A 1 561 ? 213.772 219.264 152.174 1.00 53.97  ? 561  GLY D N   1 
ATOM   4420 C CA  . GLY A 1 561 ? 215.082 219.343 151.547 1.00 53.97  ? 561  GLY D CA  1 
ATOM   4421 C C   . GLY A 1 561 ? 215.059 218.720 150.166 1.00 53.97  ? 561  GLY D C   1 
ATOM   4422 O O   . GLY A 1 561 ? 214.192 219.020 149.338 1.00 53.97  ? 561  GLY D O   1 
ATOM   4423 N N   . LYS A 1 562 ? 216.019 217.836 149.909 1.00 51.79  ? 562  LYS D N   1 
ATOM   4424 C CA  . LYS A 1 562 ? 216.131 217.149 148.630 1.00 51.79  ? 562  LYS D CA  1 
ATOM   4425 C C   . LYS A 1 562 ? 215.598 215.723 148.678 1.00 51.79  ? 562  LYS D C   1 
ATOM   4426 O O   . LYS A 1 562 ? 215.645 215.023 147.661 1.00 51.79  ? 562  LYS D O   1 
ATOM   4427 C CB  . LYS A 1 562 ? 217.592 217.146 148.166 1.00 51.79  ? 562  LYS D CB  1 
ATOM   4428 C CG  . LYS A 1 562 ? 217.777 217.092 146.657 1.00 51.79  ? 562  LYS D CG  1 
ATOM   4429 C CD  . LYS A 1 562 ? 219.248 217.153 146.282 1.00 51.79  ? 562  LYS D CD  1 
ATOM   4430 C CE  . LYS A 1 562 ? 219.435 217.133 144.775 1.00 51.79  ? 562  LYS D CE  1 
ATOM   4431 N NZ  . LYS A 1 562 ? 218.767 218.290 144.119 1.00 51.79  ? 562  LYS D NZ  1 
ATOM   4432 N N   . SER A 1 563 ? 215.087 215.277 149.828 1.00 52.82  ? 563  SER D N   1 
ATOM   4433 C CA  . SER A 1 563 ? 214.585 213.911 149.936 1.00 52.82  ? 563  SER D CA  1 
ATOM   4434 C C   . SER A 1 563 ? 213.294 213.729 149.147 1.00 52.82  ? 563  SER D C   1 
ATOM   4435 O O   . SER A 1 563 ? 213.056 212.660 148.572 1.00 52.82  ? 563  SER D O   1 
ATOM   4436 C CB  . SER A 1 563 ? 214.371 213.544 151.404 1.00 52.82  ? 563  SER D CB  1 
ATOM   4437 O OG  . SER A 1 563 ? 213.419 214.401 152.009 1.00 52.82  ? 563  SER D OG  1 
ATOM   4438 N N   . GLU A 1 564 ? 212.454 214.753 149.108 1.00 54.37  ? 564  GLU D N   1 
ATOM   4439 C CA  . GLU A 1 564 ? 211.206 214.698 148.369 1.00 54.37  ? 564  GLU D CA  1 
ATOM   4440 C C   . GLU A 1 564 ? 211.332 215.450 147.050 1.00 54.37  ? 564  GLU D C   1 
ATOM   4441 O O   . GLU A 1 564 ? 212.124 216.391 146.938 1.00 54.37  ? 564  GLU D O   1 
ATOM   4442 C CB  . GLU A 1 564 ? 210.063 215.304 149.191 1.00 54.37  ? 564  GLU D CB  1 
ATOM   4443 C CG  . GLU A 1 564 ? 209.762 214.568 150.487 1.00 54.37  ? 564  GLU D CG  1 
ATOM   4444 C CD  . GLU A 1 564 ? 209.094 213.226 150.258 1.00 54.37  ? 564  GLU D CD  1 
ATOM   4445 O OE1 . GLU A 1 564 ? 208.574 212.998 149.146 1.00 54.37  ? 564  GLU D OE1 1 
ATOM   4446 O OE2 . GLU A 1 564 ? 209.088 212.398 151.193 1.00 54.37  ? 564  GLU D OE2 1 
ATOM   4447 N N   . PRO A 1 565 ? 210.575 215.047 146.029 1.00 54.10  ? 565  PRO D N   1 
ATOM   4448 C CA  . PRO A 1 565 ? 210.602 215.784 144.761 1.00 54.10  ? 565  PRO D CA  1 
ATOM   4449 C C   . PRO A 1 565 ? 210.149 217.224 144.951 1.00 54.10  ? 565  PRO D C   1 
ATOM   4450 O O   . PRO A 1 565 ? 209.390 217.545 145.868 1.00 54.10  ? 565  PRO D O   1 
ATOM   4451 C CB  . PRO A 1 565 ? 209.627 215.002 143.873 1.00 54.10  ? 565  PRO D CB  1 
ATOM   4452 C CG  . PRO A 1 565 ? 209.589 213.634 144.468 1.00 54.10  ? 565  PRO D CG  1 
ATOM   4453 C CD  . PRO A 1 565 ? 209.744 213.835 145.946 1.00 54.10  ? 565  PRO D CD  1 
ATOM   4454 N N   . TRP A 1 566 ? 210.632 218.099 144.066 1.00 54.76  ? 566  TRP D N   1 
ATOM   4455 C CA  . TRP A 1 566 ? 210.302 219.515 144.182 1.00 54.76  ? 566  TRP D CA  1 
ATOM   4456 C C   . TRP A 1 566 ? 208.824 219.774 143.918 1.00 54.76  ? 566  TRP D C   1 
ATOM   4457 O O   . TRP A 1 566 ? 208.276 220.767 144.409 1.00 54.76  ? 566  TRP D O   1 
ATOM   4458 C CB  . TRP A 1 566 ? 211.171 220.341 143.234 1.00 54.76  ? 566  TRP D CB  1 
ATOM   4459 C CG  . TRP A 1 566 ? 211.037 219.963 141.793 1.00 54.76  ? 566  TRP D CG  1 
ATOM   4460 C CD1 . TRP A 1 566 ? 211.688 218.954 141.146 1.00 54.76  ? 566  TRP D CD1 1 
ATOM   4461 C CD2 . TRP A 1 566 ? 210.209 220.600 140.813 1.00 54.76  ? 566  TRP D CD2 1 
ATOM   4462 N NE1 . TRP A 1 566 ? 211.311 218.919 139.825 1.00 54.76  ? 566  TRP D NE1 1 
ATOM   4463 C CE2 . TRP A 1 566 ? 210.404 219.919 139.596 1.00 54.76  ? 566  TRP D CE2 1 
ATOM   4464 C CE3 . TRP A 1 566 ? 209.319 221.677 140.848 1.00 54.76  ? 566  TRP D CE3 1 
ATOM   4465 C CZ2 . TRP A 1 566 ? 209.742 220.280 138.425 1.00 54.76  ? 566  TRP D CZ2 1 
ATOM   4466 C CZ3 . TRP A 1 566 ? 208.663 222.034 139.685 1.00 54.76  ? 566  TRP D CZ3 1 
ATOM   4467 C CH2 . TRP A 1 566 ? 208.878 221.338 138.490 1.00 54.76  ? 566  TRP D CH2 1 
ATOM   4468 N N   . THR A 1 567 ? 208.162 218.898 143.160 1.00 54.66  ? 567  THR D N   1 
ATOM   4469 C CA  . THR A 1 567 ? 206.726 219.050 142.943 1.00 54.66  ? 567  THR D CA  1 
ATOM   4470 C C   . THR A 1 567 ? 205.948 218.822 144.233 1.00 54.66  ? 567  THR D C   1 
ATOM   4471 O O   . THR A 1 567 ? 204.995 219.554 144.529 1.00 54.66  ? 567  THR D O   1 
ATOM   4472 C CB  . THR A 1 567 ? 206.253 218.088 141.854 1.00 54.66  ? 567  THR D CB  1 
ATOM   4473 O OG1 . THR A 1 567 ? 206.557 216.742 142.240 1.00 54.66  ? 567  THR D OG1 1 
ATOM   4474 C CG2 . THR A 1 567 ? 206.943 218.397 140.535 1.00 54.66  ? 567  THR D CG2 1 
ATOM   4475 N N   . LEU A 1 568 ? 206.340 217.814 145.015 1.00 54.93  ? 568  LEU D N   1 
ATOM   4476 C CA  . LEU A 1 568 ? 205.691 217.581 146.300 1.00 54.93  ? 568  LEU D CA  1 
ATOM   4477 C C   . LEU A 1 568 ? 205.944 218.740 147.256 1.00 54.93  ? 568  LEU D C   1 
ATOM   4478 O O   . LEU A 1 568 ? 205.043 219.149 147.996 1.00 54.93  ? 568  LEU D O   1 
ATOM   4479 C CB  . LEU A 1 568 ? 206.177 216.260 146.900 1.00 54.93  ? 568  LEU D CB  1 
ATOM   4480 C CG  . LEU A 1 568 ? 205.381 215.646 148.056 1.00 54.93  ? 568  LEU D CG  1 
ATOM   4481 C CD1 . LEU A 1 568 ? 205.496 214.132 148.021 1.00 54.93  ? 568  LEU D CD1 1 
ATOM   4482 C CD2 . LEU A 1 568 ? 205.851 216.176 149.402 1.00 54.93  ? 568  LEU D CD2 1 
ATOM   4483 N N   . ALA A 1 569 ? 207.160 219.291 147.244 1.00 54.71  ? 569  ALA D N   1 
ATOM   4484 C CA  . ALA A 1 569 ? 207.451 220.455 148.075 1.00 54.71  ? 569  ALA D CA  1 
ATOM   4485 C C   . ALA A 1 569 ? 206.596 221.649 147.668 1.00 54.71  ? 569  ALA D C   1 
ATOM   4486 O O   . ALA A 1 569 ? 206.065 222.365 148.526 1.00 54.71  ? 569  ALA D O   1 
ATOM   4487 C CB  . ALA A 1 569 ? 208.937 220.800 147.992 1.00 54.71  ? 569  ALA D CB  1 
ATOM   4488 N N   . LEU A 1 570 ? 206.451 221.876 146.359 1.00 55.05  ? 570  LEU D N   1 
ATOM   4489 C CA  . LEU A 1 570 ? 205.590 222.952 145.878 1.00 55.05  ? 570  LEU D CA  1 
ATOM   4490 C C   . LEU A 1 570 ? 204.154 222.753 146.346 1.00 55.05  ? 570  LEU D C   1 
ATOM   4491 O O   . LEU A 1 570 ? 203.525 223.680 146.868 1.00 55.05  ? 570  LEU D O   1 
ATOM   4492 C CB  . LEU A 1 570 ? 205.651 223.037 144.353 1.00 55.05  ? 570  LEU D CB  1 
ATOM   4493 C CG  . LEU A 1 570 ? 206.893 223.680 143.737 1.00 55.05  ? 570  LEU D CG  1 
ATOM   4494 C CD1 . LEU A 1 570 ? 206.758 223.747 142.226 1.00 55.05  ? 570  LEU D CD1 1 
ATOM   4495 C CD2 . LEU A 1 570 ? 207.117 225.064 144.317 1.00 55.05  ? 570  LEU D CD2 1 
ATOM   4496 N N   . GLU A 1 571 ? 203.619 221.542 146.168 1.00 56.87  ? 571  GLU D N   1 
ATOM   4497 C CA  . GLU A 1 571 ? 202.261 221.265 146.627 1.00 56.87  ? 571  GLU D CA  1 
ATOM   4498 C C   . GLU A 1 571 ? 202.131 221.449 148.134 1.00 56.87  ? 571  GLU D C   1 
ATOM   4499 O O   . GLU A 1 571 ? 201.060 221.824 148.625 1.00 56.87  ? 571  GLU D O   1 
ATOM   4500 C CB  . GLU A 1 571 ? 201.846 219.850 146.221 1.00 56.87  ? 571  GLU D CB  1 
ATOM   4501 C CG  . GLU A 1 571 ? 200.423 219.482 146.611 1.00 56.87  ? 571  GLU D CG  1 
ATOM   4502 C CD  . GLU A 1 571 ? 199.982 218.154 146.033 1.00 56.87  ? 571  GLU D CD  1 
ATOM   4503 O OE1 . GLU A 1 571 ? 200.614 217.688 145.063 1.00 56.87  ? 571  GLU D OE1 1 
ATOM   4504 O OE2 . GLU A 1 571 ? 199.003 217.575 146.549 1.00 56.87  ? 571  GLU D OE2 1 
ATOM   4505 N N   . ASN A 1 572 ? 203.208 221.202 148.882 1.00 56.46  ? 572  ASN D N   1 
ATOM   4506 C CA  . ASN A 1 572 ? 203.162 221.404 150.325 1.00 56.46  ? 572  ASN D CA  1 
ATOM   4507 C C   . ASN A 1 572 ? 203.190 222.882 150.695 1.00 56.46  ? 572  ASN D C   1 
ATOM   4508 O O   . ASN A 1 572 ? 202.602 223.272 151.710 1.00 56.46  ? 572  ASN D O   1 
ATOM   4509 C CB  . ASN A 1 572 ? 204.325 220.674 150.998 1.00 56.46  ? 572  ASN D CB  1 
ATOM   4510 C CG  . ASN A 1 572 ? 204.158 219.169 150.980 1.00 56.46  ? 572  ASN D CG  1 
ATOM   4511 O OD1 . ASN A 1 572 ? 203.336 218.632 150.239 1.00 56.46  ? 572  ASN D OD1 1 
ATOM   4512 N ND2 . ASN A 1 572 ? 204.941 218.478 151.801 1.00 56.46  ? 572  ASN D ND2 1 
ATOM   4513 N N   . VAL A 1 573 ? 203.857 223.714 149.901 1.00 55.26  ? 573  VAL D N   1 
ATOM   4514 C CA  . VAL A 1 573 ? 204.033 225.120 150.243 1.00 55.26  ? 573  VAL D CA  1 
ATOM   4515 C C   . VAL A 1 573 ? 202.996 226.010 149.563 1.00 55.26  ? 573  VAL D C   1 
ATOM   4516 O O   . VAL A 1 573 ? 202.529 226.979 150.162 1.00 55.26  ? 573  VAL D O   1 
ATOM   4517 C CB  . VAL A 1 573 ? 205.473 225.582 149.920 1.00 55.26  ? 573  VAL D CB  1 
ATOM   4518 C CG1 . VAL A 1 573 ? 205.755 225.496 148.435 1.00 55.26  ? 573  VAL D CG1 1 
ATOM   4519 C CG2 . VAL A 1 573 ? 205.711 226.994 150.437 1.00 55.26  ? 573  VAL D CG2 1 
ATOM   4520 N N   . VAL A 1 574 ? 202.606 225.705 148.327 1.00 55.22  ? 574  VAL D N   1 
ATOM   4521 C CA  . VAL A 1 574 ? 201.636 226.530 147.618 1.00 55.22  ? 574  VAL D CA  1 
ATOM   4522 C C   . VAL A 1 574 ? 200.364 225.781 147.245 1.00 55.22  ? 574  VAL D C   1 
ATOM   4523 O O   . VAL A 1 574 ? 199.322 226.428 147.049 1.00 55.22  ? 574  VAL D O   1 
ATOM   4524 C CB  . VAL A 1 574 ? 202.257 227.177 146.359 1.00 55.22  ? 574  VAL D CB  1 
ATOM   4525 C CG1 . VAL A 1 574 ? 203.568 227.870 146.699 1.00 55.22  ? 574  VAL D CG1 1 
ATOM   4526 C CG2 . VAL A 1 574 ? 202.449 226.150 145.254 1.00 55.22  ? 574  VAL D CG2 1 
ATOM   4527 N N   . GLY A 1 575 ? 200.389 224.457 147.138 1.00 56.53  ? 575  GLY D N   1 
ATOM   4528 C CA  . GLY A 1 575 ? 199.209 223.698 146.785 1.00 56.53  ? 575  GLY D CA  1 
ATOM   4529 C C   . GLY A 1 575 ? 199.122 223.254 145.343 1.00 56.53  ? 575  GLY D C   1 
ATOM   4530 O O   . GLY A 1 575 ? 198.069 222.750 144.934 1.00 56.53  ? 575  GLY D O   1 
ATOM   4531 N N   . ALA A 1 576 ? 200.184 223.424 144.559 1.00 57.52  ? 576  ALA D N   1 
ATOM   4532 C CA  . ALA A 1 576 ? 200.204 223.001 143.168 1.00 57.52  ? 576  ALA D CA  1 
ATOM   4533 C C   . ALA A 1 576 ? 201.534 222.329 142.870 1.00 57.52  ? 576  ALA D C   1 
ATOM   4534 O O   . ALA A 1 576 ? 202.571 222.725 143.410 1.00 57.52  ? 576  ALA D O   1 
ATOM   4535 C CB  . ALA A 1 576 ? 199.985 224.183 142.216 1.00 57.52  ? 576  ALA D CB  1 
ATOM   4536 N N   . LYS A 1 577 ? 201.500 221.313 142.012 1.00 59.13  ? 577  LYS D N   1 
ATOM   4537 C CA  . LYS A 1 577 ? 202.691 220.551 141.664 1.00 59.13  ? 577  LYS D CA  1 
ATOM   4538 C C   . LYS A 1 577 ? 203.443 221.127 140.471 1.00 59.13  ? 577  LYS D C   1 
ATOM   4539 O O   . LYS A 1 577 ? 204.458 220.553 140.063 1.00 59.13  ? 577  LYS D O   1 
ATOM   4540 C CB  . LYS A 1 577 ? 202.320 219.092 141.381 1.00 59.13  ? 577  LYS D CB  1 
ATOM   4541 C CG  . LYS A 1 577 ? 201.354 218.909 140.223 1.00 59.13  ? 577  LYS D CG  1 
ATOM   4542 C CD  . LYS A 1 577 ? 201.057 217.439 139.983 1.00 59.13  ? 577  LYS D CD  1 
ATOM   4543 C CE  . LYS A 1 577 ? 200.448 216.791 141.215 1.00 59.13  ? 577  LYS D CE  1 
ATOM   4544 N NZ  . LYS A 1 577 ? 200.151 215.349 140.995 1.00 59.13  ? 577  LYS D NZ  1 
ATOM   4545 N N   . ASN A 1 578 ? 202.977 222.236 139.904 1.00 59.67  ? 578  ASN D N   1 
ATOM   4546 C CA  . ASN A 1 578 ? 203.624 222.859 138.759 1.00 59.67  ? 578  ASN D CA  1 
ATOM   4547 C C   . ASN A 1 578 ? 203.749 224.357 138.998 1.00 59.67  ? 578  ASN D C   1 
ATOM   4548 O O   . ASN A 1 578 ? 202.899 224.972 139.647 1.00 59.67  ? 578  ASN D O   1 
ATOM   4549 C CB  . ASN A 1 578 ? 202.844 222.596 137.463 1.00 59.67  ? 578  ASN D CB  1 
ATOM   4550 C CG  . ASN A 1 578 ? 203.570 223.104 136.233 1.00 59.67  ? 578  ASN D CG  1 
ATOM   4551 O OD1 . ASN A 1 578 ? 204.787 223.286 136.247 1.00 59.67  ? 578  ASN D OD1 1 
ATOM   4552 N ND2 . ASN A 1 578 ? 202.823 223.335 135.159 1.00 59.67  ? 578  ASN D ND2 1 
ATOM   4553 N N   . MET A 1 579 ? 204.823 224.937 138.468 1.00 56.10  ? 579  MET D N   1 
ATOM   4554 C CA  . MET A 1 579 ? 205.052 226.366 138.629 1.00 56.10  ? 579  MET D CA  1 
ATOM   4555 C C   . MET A 1 579 ? 204.063 227.164 137.787 1.00 56.10  ? 579  MET D C   1 
ATOM   4556 O O   . MET A 1 579 ? 203.757 226.805 136.647 1.00 56.10  ? 579  MET D O   1 
ATOM   4557 C CB  . MET A 1 579 ? 206.488 226.723 138.245 1.00 56.10  ? 579  MET D CB  1 
ATOM   4558 C CG  . MET A 1 579 ? 206.889 226.318 136.836 1.00 56.10  ? 579  MET D CG  1 
ATOM   4559 S SD  . MET A 1 579 ? 208.601 226.743 136.462 1.00 56.10  ? 579  MET D SD  1 
ATOM   4560 C CE  . MET A 1 579 ? 208.727 226.187 134.766 1.00 56.10  ? 579  MET D CE  1 
ATOM   4561 N N   . ASN A 1 580 ? 203.557 228.253 138.362 1.00 56.36  ? 580  ASN D N   1 
ATOM   4562 C CA  . ASN A 1 580 ? 202.570 229.097 137.708 1.00 56.36  ? 580  ASN D CA  1 
ATOM   4563 C C   . ASN A 1 580 ? 203.020 230.549 137.771 1.00 56.36  ? 580  ASN D C   1 
ATOM   4564 O O   . ASN A 1 580 ? 203.625 230.979 138.757 1.00 56.36  ? 580  ASN D O   1 
ATOM   4565 C CB  . ASN A 1 580 ? 201.189 228.944 138.359 1.00 56.36  ? 580  ASN D CB  1 
ATOM   4566 C CG  . ASN A 1 580 ? 200.063 229.413 137.459 1.00 56.36  ? 580  ASN D CG  1 
ATOM   4567 O OD1 . ASN A 1 580 ? 200.269 230.226 136.559 1.00 56.36  ? 580  ASN D OD1 1 
ATOM   4568 N ND2 . ASN A 1 580 ? 198.863 228.898 137.698 1.00 56.36  ? 580  ASN D ND2 1 
ATOM   4569 N N   . VAL A 1 581 ? 202.718 231.302 136.709 1.00 55.46  ? 581  VAL D N   1 
ATOM   4570 C CA  . VAL A 1 581 ? 203.111 232.707 136.633 1.00 55.46  ? 581  VAL D CA  1 
ATOM   4571 C C   . VAL A 1 581 ? 202.010 233.648 137.105 1.00 55.46  ? 581  VAL D C   1 
ATOM   4572 O O   . VAL A 1 581 ? 202.242 234.864 137.193 1.00 55.46  ? 581  VAL D O   1 
ATOM   4573 C CB  . VAL A 1 581 ? 203.535 233.064 135.193 1.00 55.46  ? 581  VAL D CB  1 
ATOM   4574 C CG1 . VAL A 1 581 ? 202.315 233.357 134.333 1.00 55.46  ? 581  VAL D CG1 1 
ATOM   4575 C CG2 . VAL A 1 581 ? 204.516 234.232 135.183 1.00 55.46  ? 581  VAL D CG2 1 
ATOM   4576 N N   . ARG A 1 582 ? 200.825 233.127 137.421 1.00 55.58  ? 582  ARG D N   1 
ATOM   4577 C CA  . ARG A 1 582 ? 199.740 233.985 137.891 1.00 55.58  ? 582  ARG D CA  1 
ATOM   4578 C C   . ARG A 1 582 ? 200.068 234.743 139.175 1.00 55.58  ? 582  ARG D C   1 
ATOM   4579 O O   . ARG A 1 582 ? 199.642 235.906 139.290 1.00 55.58  ? 582  ARG D O   1 
ATOM   4580 C CB  . ARG A 1 582 ? 198.462 233.156 138.063 1.00 55.58  ? 582  ARG D CB  1 
ATOM   4581 C CG  . ARG A 1 582 ? 197.960 232.517 136.779 1.00 55.58  ? 582  ARG D CG  1 
ATOM   4582 C CD  . ARG A 1 582 ? 197.584 233.560 135.734 1.00 55.58  ? 582  ARG D CD  1 
ATOM   4583 N NE  . ARG A 1 582 ? 196.387 234.311 136.102 1.00 55.58  ? 582  ARG D NE  1 
ATOM   4584 C CZ  . ARG A 1 582 ? 196.396 235.553 136.577 1.00 55.58  ? 582  ARG D CZ  1 
ATOM   4585 N NH1 . ARG A 1 582 ? 195.256 236.156 136.884 1.00 55.58  ? 582  ARG D NH1 1 
ATOM   4586 N NH2 . ARG A 1 582 ? 197.544 236.196 136.739 1.00 55.58  ? 582  ARG D NH2 1 
ATOM   4587 N N   . PRO A 1 583 ? 200.772 234.176 140.166 1.00 53.85  ? 583  PRO D N   1 
ATOM   4588 C CA  . PRO A 1 583 ? 201.172 235.006 141.316 1.00 53.85  ? 583  PRO D CA  1 
ATOM   4589 C C   . PRO A 1 583 ? 202.059 236.177 140.929 1.00 53.85  ? 583  PRO D C   1 
ATOM   4590 O O   . PRO A 1 583 ? 201.932 237.265 141.508 1.00 53.85  ? 583  PRO D O   1 
ATOM   4591 C CB  . PRO A 1 583 ? 201.907 234.011 142.225 1.00 53.85  ? 583  PRO D CB  1 
ATOM   4592 C CG  . PRO A 1 583 ? 201.329 232.695 141.877 1.00 53.85  ? 583  PRO D CG  1 
ATOM   4593 C CD  . PRO A 1 583 ? 201.056 232.748 140.406 1.00 53.85  ? 583  PRO D CD  1 
ATOM   4594 N N   . LEU A 1 584 ? 202.956 235.986 139.959 1.00 53.68  ? 584  LEU D N   1 
ATOM   4595 C CA  . LEU A 1 584 ? 203.807 237.084 139.514 1.00 53.68  ? 584  LEU D CA  1 
ATOM   4596 C C   . LEU A 1 584 ? 202.980 238.191 138.875 1.00 53.68  ? 584  LEU D C   1 
ATOM   4597 O O   . LEU A 1 584 ? 203.250 239.379 139.084 1.00 53.68  ? 584  LEU D O   1 
ATOM   4598 C CB  . LEU A 1 584 ? 204.866 236.562 138.539 1.00 53.68  ? 584  LEU D CB  1 
ATOM   4599 C CG  . LEU A 1 584 ? 206.137 237.386 138.309 1.00 53.68  ? 584  LEU D CG  1 
ATOM   4600 C CD1 . LEU A 1 584 ? 207.252 236.488 137.797 1.00 53.68  ? 584  LEU D CD1 1 
ATOM   4601 C CD2 . LEU A 1 584 ? 205.906 238.537 137.340 1.00 53.68  ? 584  LEU D CD2 1 
ATOM   4602 N N   . LEU A 1 585 ? 201.962 237.822 138.094 1.00 53.71  ? 585  LEU D N   1 
ATOM   4603 C CA  . LEU A 1 585 ? 201.099 238.829 137.487 1.00 53.71  ? 585  LEU D CA  1 
ATOM   4604 C C   . LEU A 1 585 ? 200.223 239.515 138.526 1.00 53.71  ? 585  LEU D C   1 
ATOM   4605 O O   . LEU A 1 585 ? 199.917 240.704 138.387 1.00 53.71  ? 585  LEU D O   1 
ATOM   4606 C CB  . LEU A 1 585 ? 200.238 238.195 136.396 1.00 53.71  ? 585  LEU D CB  1 
ATOM   4607 C CG  . LEU A 1 585 ? 200.996 237.570 135.223 1.00 53.71  ? 585  LEU D CG  1 
ATOM   4608 C CD1 . LEU A 1 585 ? 200.027 236.990 134.205 1.00 53.71  ? 585  LEU D CD1 1 
ATOM   4609 C CD2 . LEU A 1 585 ? 201.914 238.592 134.573 1.00 53.71  ? 585  LEU D CD2 1 
ATOM   4610 N N   . ASN A 1 586 ? 199.810 238.788 139.567 1.00 54.34  ? 586  ASN D N   1 
ATOM   4611 C CA  . ASN A 1 586 ? 199.051 239.413 140.645 1.00 54.34  ? 586  ASN D CA  1 
ATOM   4612 C C   . ASN A 1 586 ? 199.919 240.361 141.461 1.00 54.34  ? 586  ASN D C   1 
ATOM   4613 O O   . ASN A 1 586 ? 199.409 241.335 142.026 1.00 54.34  ? 586  ASN D O   1 
ATOM   4614 C CB  . ASN A 1 586 ? 198.437 238.345 141.550 1.00 54.34  ? 586  ASN D CB  1 
ATOM   4615 C CG  . ASN A 1 586 ? 197.391 237.510 140.839 1.00 54.34  ? 586  ASN D CG  1 
ATOM   4616 O OD1 . ASN A 1 586 ? 196.730 237.979 139.913 1.00 54.34  ? 586  ASN D OD1 1 
ATOM   4617 N ND2 . ASN A 1 586 ? 197.234 236.265 141.272 1.00 54.34  ? 586  ASN D ND2 1 
ATOM   4618 N N   . TYR A 1 587 ? 201.225 240.093 141.537 1.00 53.93  ? 587  TYR D N   1 
ATOM   4619 C CA  . TYR A 1 587 ? 202.122 240.989 142.258 1.00 53.93  ? 587  TYR D CA  1 
ATOM   4620 C C   . TYR A 1 587 ? 202.244 242.340 141.564 1.00 53.93  ? 587  TYR D C   1 
ATOM   4621 O O   . TYR A 1 587 ? 202.393 243.368 142.234 1.00 53.93  ? 587  TYR D O   1 
ATOM   4622 C CB  . TYR A 1 587 ? 203.499 240.341 142.409 1.00 53.93  ? 587  TYR D CB  1 
ATOM   4623 C CG  . TYR A 1 587 ? 204.462 241.118 143.280 1.00 53.93  ? 587  TYR D CG  1 
ATOM   4624 C CD1 . TYR A 1 587 ? 205.302 242.081 142.736 1.00 53.93  ? 587  TYR D CD1 1 
ATOM   4625 C CD2 . TYR A 1 587 ? 204.539 240.879 144.645 1.00 53.93  ? 587  TYR D CD2 1 
ATOM   4626 C CE1 . TYR A 1 587 ? 206.185 242.790 143.528 1.00 53.93  ? 587  TYR D CE1 1 
ATOM   4627 C CE2 . TYR A 1 587 ? 205.420 241.582 145.445 1.00 53.93  ? 587  TYR D CE2 1 
ATOM   4628 C CZ  . TYR A 1 587 ? 206.239 242.536 144.881 1.00 53.93  ? 587  TYR D CZ  1 
ATOM   4629 O OH  . TYR A 1 587 ? 207.117 243.238 145.674 1.00 53.93  ? 587  TYR D OH  1 
ATOM   4630 N N   . PHE A 1 588 ? 202.181 242.362 140.232 1.00 53.82  ? 588  PHE D N   1 
ATOM   4631 C CA  . PHE A 1 588 ? 202.322 243.588 139.455 1.00 53.82  ? 588  PHE D CA  1 
ATOM   4632 C C   . PHE A 1 588 ? 201.000 244.031 138.833 1.00 53.82  ? 588  PHE D C   1 
ATOM   4633 O O   . PHE A 1 588 ? 200.988 244.641 137.762 1.00 53.82  ? 588  PHE D O   1 
ATOM   4634 C CB  . PHE A 1 588 ? 203.381 243.414 138.367 1.00 53.82  ? 588  PHE D CB  1 
ATOM   4635 C CG  . PHE A 1 588 ? 204.762 243.159 138.897 1.00 53.82  ? 588  PHE D CG  1 
ATOM   4636 C CD1 . PHE A 1 588 ? 205.563 244.208 139.315 1.00 53.82  ? 588  PHE D CD1 1 
ATOM   4637 C CD2 . PHE A 1 588 ? 205.265 241.870 138.967 1.00 53.82  ? 588  PHE D CD2 1 
ATOM   4638 C CE1 . PHE A 1 588 ? 206.836 243.977 139.800 1.00 53.82  ? 588  PHE D CE1 1 
ATOM   4639 C CE2 . PHE A 1 588 ? 206.537 241.633 139.450 1.00 53.82  ? 588  PHE D CE2 1 
ATOM   4640 C CZ  . PHE A 1 588 ? 207.324 242.688 139.867 1.00 53.82  ? 588  PHE D CZ  1 
ATOM   4641 N N   . GLU A 1 589 ? 199.876 243.733 139.495 1.00 56.40  ? 589  GLU D N   1 
ATOM   4642 C CA  . GLU A 1 589 ? 198.579 244.120 138.940 1.00 56.40  ? 589  GLU D CA  1 
ATOM   4643 C C   . GLU A 1 589 ? 198.367 245.630 138.962 1.00 56.40  ? 589  GLU D C   1 
ATOM   4644 O O   . GLU A 1 589 ? 197.961 246.188 137.925 1.00 56.40  ? 589  GLU D O   1 
ATOM   4645 C CB  . GLU A 1 589 ? 197.457 243.372 139.668 1.00 56.40  ? 589  GLU D CB  1 
ATOM   4646 C CG  . GLU A 1 589 ? 196.065 243.645 139.122 1.00 56.40  ? 589  GLU D CG  1 
ATOM   4647 C CD  . GLU A 1 589 ? 195.832 243.014 137.764 1.00 56.40  ? 589  GLU D CD  1 
ATOM   4648 O OE1 . GLU A 1 589 ? 196.584 242.086 137.399 1.00 56.40  ? 589  GLU D OE1 1 
ATOM   4649 O OE2 . GLU A 1 589 ? 194.895 243.445 137.060 1.00 56.40  ? 589  GLU D OE2 1 
ATOM   4650 N N   . PRO A 1 590 ? 198.598 246.349 140.072 1.00 56.33  ? 590  PRO D N   1 
ATOM   4651 C CA  . PRO A 1 590 ? 198.476 247.816 140.003 1.00 56.33  ? 590  PRO D CA  1 
ATOM   4652 C C   . PRO A 1 590 ? 199.448 248.440 139.021 1.00 56.33  ? 590  PRO D C   1 
ATOM   4653 O O   . PRO A 1 590 ? 199.088 249.386 138.308 1.00 56.33  ? 590  PRO D O   1 
ATOM   4654 C CB  . PRO A 1 590 ? 198.758 248.260 141.446 1.00 56.33  ? 590  PRO D CB  1 
ATOM   4655 C CG  . PRO A 1 590 ? 198.467 247.065 142.277 1.00 56.33  ? 590  PRO D CG  1 
ATOM   4656 C CD  . PRO A 1 590 ? 198.892 245.899 141.445 1.00 56.33  ? 590  PRO D CD  1 
ATOM   4657 N N   . LEU A 1 591 ? 200.678 247.927 138.960 1.00 56.14  ? 591  LEU D N   1 
ATOM   4658 C CA  . LEU A 1 591 ? 201.632 248.422 137.975 1.00 56.14  ? 591  LEU D CA  1 
ATOM   4659 C C   . LEU A 1 591 ? 201.171 248.110 136.558 1.00 56.14  ? 591  LEU D C   1 
ATOM   4660 O O   . LEU A 1 591 ? 201.369 248.917 135.645 1.00 56.14  ? 591  LEU D O   1 
ATOM   4661 C CB  . LEU A 1 591 ? 203.015 247.827 138.235 1.00 56.14  ? 591  LEU D CB  1 
ATOM   4662 C CG  . LEU A 1 591 ? 204.117 248.288 137.282 1.00 56.14  ? 591  LEU D CG  1 
ATOM   4663 C CD1 . LEU A 1 591 ? 204.279 249.799 137.342 1.00 56.14  ? 591  LEU D CD1 1 
ATOM   4664 C CD2 . LEU A 1 591 ? 205.422 247.595 137.612 1.00 56.14  ? 591  LEU D CD2 1 
ATOM   4665 N N   . PHE A 1 592 ? 200.551 246.945 136.356 1.00 56.14  ? 592  PHE D N   1 
ATOM   4666 C CA  . PHE A 1 592 ? 200.007 246.611 135.043 1.00 56.14  ? 592  PHE D CA  1 
ATOM   4667 C C   . PHE A 1 592 ? 198.930 247.609 134.633 1.00 56.14  ? 592  PHE D C   1 
ATOM   4668 O O   . PHE A 1 592 ? 198.921 248.104 133.499 1.00 56.14  ? 592  PHE D O   1 
ATOM   4669 C CB  . PHE A 1 592 ? 199.448 245.187 135.058 1.00 56.14  ? 592  PHE D CB  1 
ATOM   4670 C CG  . PHE A 1 592 ? 199.284 244.576 133.693 1.00 56.14  ? 592  PHE D CG  1 
ATOM   4671 C CD1 . PHE A 1 592 ? 199.734 245.232 132.559 1.00 56.14  ? 592  PHE D CD1 1 
ATOM   4672 C CD2 . PHE A 1 592 ? 198.673 243.342 133.546 1.00 56.14  ? 592  PHE D CD2 1 
ATOM   4673 C CE1 . PHE A 1 592 ? 199.580 244.667 131.308 1.00 56.14  ? 592  PHE D CE1 1 
ATOM   4674 C CE2 . PHE A 1 592 ? 198.516 242.773 132.298 1.00 56.14  ? 592  PHE D CE2 1 
ATOM   4675 C CZ  . PHE A 1 592 ? 198.970 243.437 131.177 1.00 56.14  ? 592  PHE D CZ  1 
ATOM   4676 N N   . THR A 1 593 ? 198.011 247.919 135.552 1.00 57.13  ? 593  THR D N   1 
ATOM   4677 C CA  . THR A 1 593 ? 196.964 248.889 135.248 1.00 57.13  ? 593  THR D CA  1 
ATOM   4678 C C   . THR A 1 593 ? 197.552 250.268 134.968 1.00 57.13  ? 593  THR D C   1 
ATOM   4679 O O   . THR A 1 593 ? 197.121 250.960 134.038 1.00 57.13  ? 593  THR D O   1 
ATOM   4680 C CB  . THR A 1 593 ? 195.959 248.960 136.398 1.00 57.13  ? 593  THR D CB  1 
ATOM   4681 O OG1 . THR A 1 593 ? 196.636 249.330 137.605 1.00 57.13  ? 593  THR D OG1 1 
ATOM   4682 C CG2 . THR A 1 593 ? 195.280 247.614 136.595 1.00 57.13  ? 593  THR D CG2 1 
ATOM   4683 N N   . TRP A 1 594 ? 198.549 250.678 135.755 1.00 59.20  ? 594  TRP D N   1 
ATOM   4684 C CA  . TRP A 1 594 ? 199.161 251.987 135.548 1.00 59.20  ? 594  TRP D CA  1 
ATOM   4685 C C   . TRP A 1 594 ? 199.885 252.057 134.208 1.00 59.20  ? 594  TRP D C   1 
ATOM   4686 O O   . TRP A 1 594 ? 199.832 253.084 133.522 1.00 59.20  ? 594  TRP D O   1 
ATOM   4687 C CB  . TRP A 1 594 ? 200.117 252.305 136.697 1.00 59.20  ? 594  TRP D CB  1 
ATOM   4688 C CG  . TRP A 1 594 ? 200.661 253.698 136.652 1.00 59.20  ? 594  TRP D CG  1 
ATOM   4689 C CD1 . TRP A 1 594 ? 200.062 254.827 137.129 1.00 59.20  ? 594  TRP D CD1 1 
ATOM   4690 C CD2 . TRP A 1 594 ? 201.916 254.111 136.102 1.00 59.20  ? 594  TRP D CD2 1 
ATOM   4691 N NE1 . TRP A 1 594 ? 200.866 255.918 136.909 1.00 59.20  ? 594  TRP D NE1 1 
ATOM   4692 C CE2 . TRP A 1 594 ? 202.011 255.506 136.280 1.00 59.20  ? 594  TRP D CE2 1 
ATOM   4693 C CE3 . TRP A 1 594 ? 202.970 253.439 135.476 1.00 59.20  ? 594  TRP D CE3 1 
ATOM   4694 C CZ2 . TRP A 1 594 ? 203.116 256.239 135.855 1.00 59.20  ? 594  TRP D CZ2 1 
ATOM   4695 C CZ3 . TRP A 1 594 ? 204.065 254.168 135.054 1.00 59.20  ? 594  TRP D CZ3 1 
ATOM   4696 C CH2 . TRP A 1 594 ? 204.130 255.553 135.245 1.00 59.20  ? 594  TRP D CH2 1 
ATOM   4697 N N   . LEU A 1 595 ? 200.560 250.975 133.814 1.00 58.98  ? 595  LEU D N   1 
ATOM   4698 C CA  . LEU A 1 595 ? 201.254 250.963 132.530 1.00 58.98  ? 595  LEU D CA  1 
ATOM   4699 C C   . LEU A 1 595 ? 200.267 250.957 131.370 1.00 58.98  ? 595  LEU D C   1 
ATOM   4700 O O   . LEU A 1 595 ? 200.511 251.596 130.340 1.00 58.98  ? 595  LEU D O   1 
ATOM   4701 C CB  . LEU A 1 595 ? 202.190 249.758 132.446 1.00 58.98  ? 595  LEU D CB  1 
ATOM   4702 C CG  . LEU A 1 595 ? 203.433 249.797 133.336 1.00 58.98  ? 595  LEU D CG  1 
ATOM   4703 C CD1 . LEU A 1 595 ? 204.265 248.538 133.152 1.00 58.98  ? 595  LEU D CD1 1 
ATOM   4704 C CD2 . LEU A 1 595 ? 204.262 251.038 133.045 1.00 58.98  ? 595  LEU D CD2 1 
ATOM   4705 N N   . LYS A 1 596 ? 199.150 250.240 131.514 1.00 59.46  ? 596  LYS D N   1 
ATOM   4706 C CA  . LYS A 1 596 ? 198.116 250.294 130.486 1.00 59.46  ? 596  LYS D CA  1 
ATOM   4707 C C   . LYS A 1 596 ? 197.505 251.685 130.391 1.00 59.46  ? 596  LYS D C   1 
ATOM   4708 O O   . LYS A 1 596 ? 197.112 252.118 129.301 1.00 59.46  ? 596  LYS D O   1 
ATOM   4709 C CB  . LYS A 1 596 ? 197.030 249.254 130.767 1.00 59.46  ? 596  LYS D CB  1 
ATOM   4710 C CG  . LYS A 1 596 ? 197.487 247.816 130.596 1.00 59.46  ? 596  LYS D CG  1 
ATOM   4711 C CD  . LYS A 1 596 ? 196.331 246.845 130.776 1.00 59.46  ? 596  LYS D CD  1 
ATOM   4712 C CE  . LYS A 1 596 ? 195.706 246.980 132.154 1.00 59.46  ? 596  LYS D CE  1 
ATOM   4713 N NZ  . LYS A 1 596 ? 194.576 246.031 132.344 1.00 59.46  ? 596  LYS D NZ  1 
ATOM   4714 N N   . ASP A 1 597 ? 197.419 252.398 131.516 1.00 65.02  ? 597  ASP D N   1 
ATOM   4715 C CA  . ASP A 1 597 ? 196.894 253.759 131.487 1.00 65.02  ? 597  ASP D CA  1 
ATOM   4716 C C   . ASP A 1 597 ? 197.894 254.738 130.884 1.00 65.02  ? 597  ASP D C   1 
ATOM   4717 O O   . ASP A 1 597 ? 197.491 255.716 130.243 1.00 65.02  ? 597  ASP D O   1 
ATOM   4718 C CB  . ASP A 1 597 ? 196.503 254.199 132.897 1.00 65.02  ? 597  ASP D CB  1 
ATOM   4719 C CG  . ASP A 1 597 ? 195.964 255.615 132.937 1.00 65.02  ? 597  ASP D CG  1 
ATOM   4720 O OD1 . ASP A 1 597 ? 194.853 255.844 132.416 1.00 65.02  ? 597  ASP D OD1 1 
ATOM   4721 O OD2 . ASP A 1 597 ? 196.652 256.498 133.490 1.00 65.02  ? 597  ASP D OD2 1 
ATOM   4722 N N   . GLN A 1 598 ? 199.189 254.500 131.075 1.00 63.53  ? 598  GLN D N   1 
ATOM   4723 C CA  . GLN A 1 598 ? 200.227 255.392 130.575 1.00 63.53  ? 598  GLN D CA  1 
ATOM   4724 C C   . GLN A 1 598 ? 200.648 255.086 129.143 1.00 63.53  ? 598  GLN D C   1 
ATOM   4725 O O   . GLN A 1 598 ? 201.461 255.827 128.583 1.00 63.53  ? 598  GLN D O   1 
ATOM   4726 C CB  . GLN A 1 598 ? 201.456 255.338 131.489 1.00 63.53  ? 598  GLN D CB  1 
ATOM   4727 C CG  . GLN A 1 598 ? 201.232 255.924 132.872 1.00 63.53  ? 598  GLN D CG  1 
ATOM   4728 C CD  . GLN A 1 598 ? 201.070 257.431 132.853 1.00 63.53  ? 598  GLN D CD  1 
ATOM   4729 O OE1 . GLN A 1 598 ? 201.428 258.094 131.880 1.00 63.53  ? 598  GLN D OE1 1 
ATOM   4730 N NE2 . GLN A 1 598 ? 200.528 257.981 133.933 1.00 63.53  ? 598  GLN D NE2 1 
ATOM   4731 N N   . ASN A 1 599 ? 200.123 254.023 128.540 1.00 66.88  ? 599  ASN D N   1 
ATOM   4732 C CA  . ASN A 1 599 ? 200.468 253.633 127.179 1.00 66.88  ? 599  ASN D CA  1 
ATOM   4733 C C   . ASN A 1 599 ? 199.254 253.715 126.261 1.00 66.88  ? 599  ASN D C   1 
ATOM   4734 O O   . ASN A 1 599 ? 199.029 252.844 125.418 1.00 66.88  ? 599  ASN D O   1 
ATOM   4735 C CB  . ASN A 1 599 ? 201.068 252.229 127.149 1.00 66.88  ? 599  ASN D CB  1 
ATOM   4736 C CG  . ASN A 1 599 ? 202.389 252.145 127.887 1.00 66.88  ? 599  ASN D CG  1 
ATOM   4737 O OD1 . ASN A 1 599 ? 203.143 253.116 127.946 1.00 66.88  ? 599  ASN D OD1 1 
ATOM   4738 N ND2 . ASN A 1 599 ? 202.677 250.980 128.453 1.00 66.88  ? 599  ASN D ND2 1 
ATOM   4739 N N   . LYS A 1 600 ? 198.454 254.771 126.415 1.00 71.57  ? 600  LYS D N   1 
ATOM   4740 C CA  . LYS A 1 600 ? 197.281 254.937 125.562 1.00 71.57  ? 600  LYS D CA  1 
ATOM   4741 C C   . LYS A 1 600 ? 197.681 255.390 124.164 1.00 71.57  ? 600  LYS D C   1 
ATOM   4742 O O   . LYS A 1 600 ? 197.184 254.862 123.162 1.00 71.57  ? 600  LYS D O   1 
ATOM   4743 C CB  . LYS A 1 600 ? 196.307 255.931 126.195 1.00 71.57  ? 600  LYS D CB  1 
ATOM   4744 C CG  . LYS A 1 600 ? 195.727 255.472 127.522 1.00 71.57  ? 600  LYS D CG  1 
ATOM   4745 C CD  . LYS A 1 600 ? 194.756 256.497 128.083 1.00 71.57  ? 600  LYS D CD  1 
ATOM   4746 C CE  . LYS A 1 600 ? 195.435 257.839 128.303 1.00 71.57  ? 600  LYS D CE  1 
ATOM   4747 N NZ  . LYS A 1 600 ? 196.573 257.736 129.258 1.00 71.57  ? 600  LYS D NZ  1 
ATOM   4748 N N   . ASN A 1 601 ? 198.580 256.369 124.076 1.00 75.92  ? 601  ASN D N   1 
ATOM   4749 C CA  . ASN A 1 601 ? 199.030 256.875 122.786 1.00 75.92  ? 601  ASN D CA  1 
ATOM   4750 C C   . ASN A 1 601 ? 200.261 256.149 122.265 1.00 75.92  ? 601  ASN D C   1 
ATOM   4751 O O   . ASN A 1 601 ? 200.485 256.120 121.049 1.00 75.92  ? 601  ASN D O   1 
ATOM   4752 C CB  . ASN A 1 601 ? 199.325 258.375 122.881 1.00 75.92  ? 601  ASN D CB  1 
ATOM   4753 C CG  . ASN A 1 601 ? 200.380 258.696 123.922 1.00 75.92  ? 601  ASN D CG  1 
ATOM   4754 O OD1 . ASN A 1 601 ? 200.071 258.884 125.098 1.00 75.92  ? 601  ASN D OD1 1 
ATOM   4755 N ND2 . ASN A 1 601 ? 201.635 258.763 123.492 1.00 75.92  ? 601  ASN D ND2 1 
ATOM   4756 N N   . SER A 1 602 ? 201.062 255.564 123.151 1.00 70.77  ? 602  SER D N   1 
ATOM   4757 C CA  . SER A 1 602 ? 202.257 254.852 122.725 1.00 70.77  ? 602  SER D CA  1 
ATOM   4758 C C   . SER A 1 602 ? 201.887 253.543 122.037 1.00 70.77  ? 602  SER D C   1 
ATOM   4759 O O   . SER A 1 602 ? 200.837 252.950 122.296 1.00 70.77  ? 602  SER D O   1 
ATOM   4760 C CB  . SER A 1 602 ? 203.168 254.575 123.920 1.00 70.77  ? 602  SER D CB  1 
ATOM   4761 O OG  . SER A 1 602 ? 203.570 255.781 124.545 1.00 70.77  ? 602  SER D OG  1 
ATOM   4762 N N   . PHE A 1 603 ? 202.769 253.095 121.147 1.00 65.81  ? 603  PHE D N   1 
ATOM   4763 C CA  . PHE A 1 603 ? 202.571 251.854 120.405 1.00 65.81  ? 603  PHE D CA  1 
ATOM   4764 C C   . PHE A 1 603 ? 203.126 250.699 121.230 1.00 65.81  ? 603  PHE D C   1 
ATOM   4765 O O   . PHE A 1 603 ? 204.345 250.563 121.382 1.00 65.81  ? 603  PHE D O   1 
ATOM   4766 C CB  . PHE A 1 603 ? 203.245 251.932 119.038 1.00 65.81  ? 603  PHE D CB  1 
ATOM   4767 C CG  . PHE A 1 603 ? 203.142 250.666 118.237 1.00 65.81  ? 603  PHE D CG  1 
ATOM   4768 C CD1 . PHE A 1 603 ? 201.989 250.370 117.530 1.00 65.81  ? 603  PHE D CD1 1 
ATOM   4769 C CD2 . PHE A 1 603 ? 204.202 249.775 118.185 1.00 65.81  ? 603  PHE D CD2 1 
ATOM   4770 C CE1 . PHE A 1 603 ? 201.892 249.207 116.791 1.00 65.81  ? 603  PHE D CE1 1 
ATOM   4771 C CE2 . PHE A 1 603 ? 204.111 248.611 117.447 1.00 65.81  ? 603  PHE D CE2 1 
ATOM   4772 C CZ  . PHE A 1 603 ? 202.955 248.326 116.749 1.00 65.81  ? 603  PHE D CZ  1 
ATOM   4773 N N   . VAL A 1 604 ? 202.235 249.869 121.763 1.00 63.56  ? 604  VAL D N   1 
ATOM   4774 C CA  . VAL A 1 604 ? 202.645 248.713 122.551 1.00 63.56  ? 604  VAL D CA  1 
ATOM   4775 C C   . VAL A 1 604 ? 203.176 247.637 121.612 1.00 63.56  ? 604  VAL D C   1 
ATOM   4776 O O   . VAL A 1 604 ? 202.576 247.351 120.569 1.00 63.56  ? 604  VAL D O   1 
ATOM   4777 C CB  . VAL A 1 604 ? 201.476 248.194 123.406 1.00 63.56  ? 604  VAL D CB  1 
ATOM   4778 C CG1 . VAL A 1 604 ? 200.232 247.986 122.552 1.00 63.56  ? 604  VAL D CG1 1 
ATOM   4779 C CG2 . VAL A 1 604 ? 201.863 246.908 124.123 1.00 63.56  ? 604  VAL D CG2 1 
ATOM   4780 N N   . GLY A 1 605 ? 204.309 247.049 121.972 1.00 62.50  ? 605  GLY D N   1 
ATOM   4781 C CA  . GLY A 1 605 ? 204.950 246.048 121.145 1.00 62.50  ? 605  GLY D CA  1 
ATOM   4782 C C   . GLY A 1 605 ? 206.170 246.592 120.431 1.00 62.50  ? 605  GLY D C   1 
ATOM   4783 O O   . GLY A 1 605 ? 206.627 247.716 120.661 1.00 62.50  ? 605  GLY D O   1 
ATOM   4784 N N   . TRP A 1 606 ? 206.705 245.762 119.540 1.00 61.25  ? 606  TRP D N   1 
ATOM   4785 C CA  . TRP A 1 606 ? 207.886 246.131 118.774 1.00 61.25  ? 606  TRP D CA  1 
ATOM   4786 C C   . TRP A 1 606 ? 207.875 245.391 117.446 1.00 61.25  ? 606  TRP D C   1 
ATOM   4787 O O   . TRP A 1 606 ? 207.209 244.365 117.287 1.00 61.25  ? 606  TRP D O   1 
ATOM   4788 C CB  . TRP A 1 606 ? 209.177 245.831 119.546 1.00 61.25  ? 606  TRP D CB  1 
ATOM   4789 C CG  . TRP A 1 606 ? 209.325 244.394 119.948 1.00 61.25  ? 606  TRP D CG  1 
ATOM   4790 C CD1 . TRP A 1 606 ? 209.805 243.373 119.181 1.00 61.25  ? 606  TRP D CD1 1 
ATOM   4791 C CD2 . TRP A 1 606 ? 208.998 243.820 121.220 1.00 61.25  ? 606  TRP D CD2 1 
ATOM   4792 N NE1 . TRP A 1 606 ? 209.794 242.199 119.894 1.00 61.25  ? 606  TRP D NE1 1 
ATOM   4793 C CE2 . TRP A 1 606 ? 209.303 242.447 121.149 1.00 61.25  ? 606  TRP D CE2 1 
ATOM   4794 C CE3 . TRP A 1 606 ? 208.476 244.334 122.410 1.00 61.25  ? 606  TRP D CE3 1 
ATOM   4795 C CZ2 . TRP A 1 606 ? 209.103 241.582 122.222 1.00 61.25  ? 606  TRP D CZ2 1 
ATOM   4796 C CZ3 . TRP A 1 606 ? 208.279 243.474 123.474 1.00 61.25  ? 606  TRP D CZ3 1 
ATOM   4797 C CH2 . TRP A 1 606 ? 208.592 242.113 123.373 1.00 61.25  ? 606  TRP D CH2 1 
ATOM   4798 N N   . SER A 1 607 ? 208.626 245.931 116.490 1.00 68.05  ? 607  SER D N   1 
ATOM   4799 C CA  . SER A 1 607 ? 208.765 245.346 115.165 1.00 68.05  ? 607  SER D CA  1 
ATOM   4800 C C   . SER A 1 607 ? 210.222 244.983 114.923 1.00 68.05  ? 607  SER D C   1 
ATOM   4801 O O   . SER A 1 607 ? 211.128 245.757 115.250 1.00 68.05  ? 607  SER D O   1 
ATOM   4802 C CB  . SER A 1 607 ? 208.273 246.309 114.080 1.00 68.05  ? 607  SER D CB  1 
ATOM   4803 O OG  . SER A 1 607 ? 208.424 245.744 112.790 1.00 68.05  ? 607  SER D OG  1 
ATOM   4804 N N   . THR A 1 608 ? 210.443 243.802 114.349 1.00 69.92  ? 608  THR D N   1 
ATOM   4805 C CA  . THR A 1 608 ? 211.790 243.289 114.134 1.00 69.92  ? 608  THR D CA  1 
ATOM   4806 C C   . THR A 1 608 ? 212.445 243.825 112.867 1.00 69.92  ? 608  THR D C   1 
ATOM   4807 O O   . THR A 1 608 ? 213.618 243.524 112.624 1.00 69.92  ? 608  THR D O   1 
ATOM   4808 C CB  . THR A 1 608 ? 211.767 241.759 114.086 1.00 69.92  ? 608  THR D CB  1 
ATOM   4809 O OG1 . THR A 1 608 ? 210.927 241.324 113.010 1.00 69.92  ? 608  THR D OG1 1 
ATOM   4810 C CG2 . THR A 1 608 ? 211.236 241.195 115.395 1.00 69.92  ? 608  THR D CG2 1 
ATOM   4811 N N   . ASP A 1 609 ? 211.728 244.603 112.055 1.00 75.62  ? 609  ASP D N   1 
ATOM   4812 C CA  . ASP A 1 609 ? 212.312 245.139 110.833 1.00 75.62  ? 609  ASP D CA  1 
ATOM   4813 C C   . ASP A 1 609 ? 213.196 246.353 111.087 1.00 75.62  ? 609  ASP D C   1 
ATOM   4814 O O   . ASP A 1 609 ? 214.072 246.646 110.266 1.00 75.62  ? 609  ASP D O   1 
ATOM   4815 C CB  . ASP A 1 609 ? 211.211 245.506 109.835 1.00 75.62  ? 609  ASP D CB  1 
ATOM   4816 C CG  . ASP A 1 609 ? 210.335 246.642 110.325 1.00 75.62  ? 609  ASP D CG  1 
ATOM   4817 O OD1 . ASP A 1 609 ? 210.190 246.796 111.555 1.00 75.62  ? 609  ASP D OD1 1 
ATOM   4818 O OD2 . ASP A 1 609 ? 209.792 247.383 109.478 1.00 75.62  ? 609  ASP D OD2 1 
ATOM   4819 N N   . TRP A 1 610 ? 212.991 247.058 112.195 1.00 71.38  ? 610  TRP D N   1 
ATOM   4820 C CA  . TRP A 1 610 ? 213.784 248.238 112.501 1.00 71.38  ? 610  TRP D CA  1 
ATOM   4821 C C   . TRP A 1 610 ? 215.161 247.844 113.020 1.00 71.38  ? 610  TRP D C   1 
ATOM   4822 O O   . TRP A 1 610 ? 215.327 246.831 113.705 1.00 71.38  ? 610  TRP D O   1 
ATOM   4823 C CB  . TRP A 1 610 ? 213.068 249.114 113.530 1.00 71.38  ? 610  TRP D CB  1 
ATOM   4824 C CG  . TRP A 1 610 ? 213.894 250.265 114.020 1.00 71.38  ? 610  TRP D CG  1 
ATOM   4825 C CD1 . TRP A 1 610 ? 214.605 250.326 115.183 1.00 71.38  ? 610  TRP D CD1 1 
ATOM   4826 C CD2 . TRP A 1 610 ? 214.101 251.517 113.357 1.00 71.38  ? 610  TRP D CD2 1 
ATOM   4827 N NE1 . TRP A 1 610 ? 215.240 251.540 115.286 1.00 71.38  ? 610  TRP D NE1 1 
ATOM   4828 C CE2 . TRP A 1 610 ? 214.946 252.290 114.178 1.00 71.38  ? 610  TRP D CE2 1 
ATOM   4829 C CE3 . TRP A 1 610 ? 213.653 252.061 112.149 1.00 71.38  ? 610  TRP D CE3 1 
ATOM   4830 C CZ2 . TRP A 1 610 ? 215.351 253.577 113.831 1.00 71.38  ? 610  TRP D CZ2 1 
ATOM   4831 C CZ3 . TRP A 1 610 ? 214.056 253.339 111.807 1.00 71.38  ? 610  TRP D CZ3 1 
ATOM   4832 C CH2 . TRP A 1 610 ? 214.897 254.082 112.644 1.00 71.38  ? 610  TRP D CH2 1 
ATOM   4833 N N   . SER A 1 611 ? 216.155 248.664 112.683 1.00 72.60  ? 611  SER D N   1 
ATOM   4834 C CA  . SER A 1 611 ? 217.527 248.439 113.114 1.00 72.60  ? 611  SER D CA  1 
ATOM   4835 C C   . SER A 1 611 ? 218.254 249.773 113.112 1.00 72.60  ? 611  SER D C   1 
ATOM   4836 O O   . SER A 1 611 ? 217.970 250.625 112.262 1.00 72.60  ? 611  SER D O   1 
ATOM   4837 C CB  . SER A 1 611 ? 218.241 247.437 112.195 1.00 72.60  ? 611  SER D CB  1 
ATOM   4838 O OG  . SER A 1 611 ? 219.568 247.199 112.632 1.00 72.60  ? 611  SER D OG  1 
ATOM   4839 N N   . PRO A 1 612 ? 219.187 249.988 114.039 1.00 71.65  ? 612  PRO D N   1 
ATOM   4840 C CA  . PRO A 1 612 ? 219.938 251.249 114.075 1.00 71.65  ? 612  PRO D CA  1 
ATOM   4841 C C   . PRO A 1 612 ? 221.011 251.378 113.006 1.00 71.65  ? 612  PRO D C   1 
ATOM   4842 O O   . PRO A 1 612 ? 221.848 252.279 113.107 1.00 71.65  ? 612  PRO D O   1 
ATOM   4843 C CB  . PRO A 1 612 ? 220.578 251.227 115.476 1.00 71.65  ? 612  PRO D CB  1 
ATOM   4844 C CG  . PRO A 1 612 ? 219.837 250.175 116.244 1.00 71.65  ? 612  PRO D CG  1 
ATOM   4845 C CD  . PRO A 1 612 ? 219.446 249.160 115.227 1.00 71.65  ? 612  PRO D CD  1 
ATOM   4846 N N   . TYR A 1 613 ? 221.017 250.510 111.999 1.00 71.61  ? 613  TYR D N   1 
ATOM   4847 C CA  . TYR A 1 613 ? 222.024 250.555 110.945 1.00 71.61  ? 613  TYR D CA  1 
ATOM   4848 C C   . TYR A 1 613 ? 221.905 251.836 110.125 1.00 71.61  ? 613  TYR D C   1 
ATOM   4849 O O   . TYR A 1 613 ? 220.970 251.998 109.342 1.00 71.61  ? 613  TYR D O   1 
ATOM   4850 C CB  . TYR A 1 613 ? 221.899 249.335 110.027 1.00 71.61  ? 613  TYR D CB  1 
ATOM   4851 C CG  . TYR A 1 613 ? 222.062 248.005 110.730 1.00 71.61  ? 613  TYR D CG  1 
ATOM   4852 C CD1 . TYR A 1 613 ? 221.552 246.839 110.173 1.00 71.61  ? 613  TYR D CD1 1 
ATOM   4853 C CD2 . TYR A 1 613 ? 222.727 247.912 111.945 1.00 71.61  ? 613  TYR D CD2 1 
ATOM   4854 C CE1 . TYR A 1 613 ? 221.697 245.621 110.807 1.00 71.61  ? 613  TYR D CE1 1 
ATOM   4855 C CE2 . TYR A 1 613 ? 222.875 246.698 112.588 1.00 71.61  ? 613  TYR D CE2 1 
ATOM   4856 C CZ  . TYR A 1 613 ? 222.360 245.556 112.014 1.00 71.61  ? 613  TYR D CZ  1 
ATOM   4857 O OH  . TYR A 1 613 ? 222.506 244.345 112.649 1.00 71.61  ? 613  TYR D OH  1 
ATOM   4858 N N   . GLN B 2 14  ? 250.851 178.944 191.098 1.00 97.79  ? 14   GLN C N   1 
ATOM   4859 C CA  . GLN B 2 14  ? 251.576 179.627 192.162 1.00 97.79  ? 14   GLN C CA  1 
ATOM   4860 C C   . GLN B 2 14  ? 251.520 178.810 193.449 1.00 97.79  ? 14   GLN C C   1 
ATOM   4861 O O   . GLN B 2 14  ? 252.451 178.838 194.254 1.00 97.79  ? 14   GLN C O   1 
ATOM   4862 C CB  . GLN B 2 14  ? 251.001 181.029 192.388 1.00 97.79  ? 14   GLN C CB  1 
ATOM   4863 C CG  . GLN B 2 14  ? 251.873 181.946 193.238 1.00 97.79  ? 14   GLN C CG  1 
ATOM   4864 C CD  . GLN B 2 14  ? 251.640 181.772 194.726 1.00 97.79  ? 14   GLN C CD  1 
ATOM   4865 O OE1 . GLN B 2 14  ? 250.636 181.197 195.147 1.00 97.79  ? 14   GLN C OE1 1 
ATOM   4866 N NE2 . GLN B 2 14  ? 252.571 182.269 195.532 1.00 97.79  ? 14   GLN C NE2 1 
ATOM   4867 N N   . CYS B 2 15  ? 250.421 178.084 193.633 1.00 97.88  ? 15   CYS C N   1 
ATOM   4868 C CA  . CYS B 2 15  ? 250.259 177.258 194.821 1.00 97.88  ? 15   CYS C CA  1 
ATOM   4869 C C   . CYS B 2 15  ? 251.246 176.099 194.815 1.00 97.88  ? 15   CYS C C   1 
ATOM   4870 O O   . CYS B 2 15  ? 251.562 175.532 193.765 1.00 97.88  ? 15   CYS C O   1 
ATOM   4871 C CB  . CYS B 2 15  ? 248.831 176.723 194.904 1.00 97.88  ? 15   CYS C CB  1 
ATOM   4872 S SG  . CYS B 2 15  ? 247.620 177.912 195.511 1.00 97.88  ? 15   CYS C SG  1 
ATOM   4873 N N   . VAL B 2 16  ? 251.734 175.748 196.002 1.00 93.15  ? 16   VAL C N   1 
ATOM   4874 C CA  . VAL B 2 16  ? 252.661 174.639 196.185 1.00 93.15  ? 16   VAL C CA  1 
ATOM   4875 C C   . VAL B 2 16  ? 252.122 173.746 197.291 1.00 93.15  ? 16   VAL C C   1 
ATOM   4876 O O   . VAL B 2 16  ? 251.842 174.223 198.397 1.00 93.15  ? 16   VAL C O   1 
ATOM   4877 C CB  . VAL B 2 16  ? 254.082 175.126 196.529 1.00 93.15  ? 16   VAL C CB  1 
ATOM   4878 C CG1 . VAL B 2 16  ? 255.008 173.941 196.745 1.00 93.15  ? 16   VAL C CG1 1 
ATOM   4879 C CG2 . VAL B 2 16  ? 254.618 176.033 195.432 1.00 93.15  ? 16   VAL C CG2 1 
ATOM   4880 N N   . ASN B 2 17  ? 251.976 172.458 196.995 1.00 93.19  ? 17   ASN C N   1 
ATOM   4881 C CA  . ASN B 2 17  ? 251.512 171.509 197.993 1.00 93.19  ? 17   ASN C CA  1 
ATOM   4882 C C   . ASN B 2 17  ? 252.586 171.289 199.057 1.00 93.19  ? 17   ASN C C   1 
ATOM   4883 O O   . ASN B 2 17  ? 253.724 171.755 198.944 1.00 93.19  ? 17   ASN C O   1 
ATOM   4884 C CB  . ASN B 2 17  ? 251.130 170.184 197.337 1.00 93.19  ? 17   ASN C CB  1 
ATOM   4885 C CG  . ASN B 2 17  ? 249.859 170.283 196.513 1.00 93.19  ? 17   ASN C CG  1 
ATOM   4886 O OD1 . ASN B 2 17  ? 249.337 171.373 196.280 1.00 93.19  ? 17   ASN C OD1 1 
ATOM   4887 N ND2 . ASN B 2 17  ? 249.359 169.137 196.065 1.00 93.19  ? 17   ASN C ND2 1 
ATOM   4888 N N   . LEU B 2 18  ? 252.212 170.559 200.105 1.00 88.90  ? 18   LEU C N   1 
ATOM   4889 C CA  . LEU B 2 18  ? 253.095 170.302 201.236 1.00 88.90  ? 18   LEU C CA  1 
ATOM   4890 C C   . LEU B 2 18  ? 253.184 168.802 201.466 1.00 88.90  ? 18   LEU C C   1 
ATOM   4891 O O   . LEU B 2 18  ? 252.161 168.145 201.688 1.00 88.90  ? 18   LEU C O   1 
ATOM   4892 C CB  . LEU B 2 18  ? 252.595 171.012 202.497 1.00 88.90  ? 18   LEU C CB  1 
ATOM   4893 C CG  . LEU B 2 18  ? 252.505 172.536 202.403 1.00 88.90  ? 18   LEU C CG  1 
ATOM   4894 C CD1 . LEU B 2 18  ? 251.982 173.124 203.702 1.00 88.90  ? 18   LEU C CD1 1 
ATOM   4895 C CD2 . LEU B 2 18  ? 253.859 173.128 202.047 1.00 88.90  ? 18   LEU C CD2 1 
ATOM   4896 N N   . THR B 2 19  ? 254.398 168.268 201.415 1.00 87.81  ? 19   THR C N   1 
ATOM   4897 C CA  . THR B 2 19  ? 254.665 166.859 201.653 1.00 87.81  ? 19   THR C CA  1 
ATOM   4898 C C   . THR B 2 19  ? 255.356 166.695 203.004 1.00 87.81  ? 19   THR C C   1 
ATOM   4899 O O   . THR B 2 19  ? 255.548 167.661 203.750 1.00 87.81  ? 19   THR C O   1 
ATOM   4900 C CB  . THR B 2 19  ? 255.510 166.273 200.518 1.00 87.81  ? 19   THR C CB  1 
ATOM   4901 O OG1 . THR B 2 19  ? 255.314 167.047 199.329 1.00 87.81  ? 19   THR C OG1 1 
ATOM   4902 C CG2 . THR B 2 19  ? 255.102 164.832 200.234 1.00 87.81  ? 19   THR C CG2 1 
ATOM   4903 N N   . THR B 2 20  ? 255.729 165.451 203.313 1.00 87.28  ? 20   THR C N   1 
ATOM   4904 C CA  . THR B 2 20  ? 256.382 165.102 204.576 1.00 87.28  ? 20   THR C CA  1 
ATOM   4905 C C   . THR B 2 20  ? 255.524 165.530 205.767 1.00 87.28  ? 20   THR C C   1 
ATOM   4906 O O   . THR B 2 20  ? 255.998 166.154 206.719 1.00 87.28  ? 20   THR C O   1 
ATOM   4907 C CB  . THR B 2 20  ? 257.788 165.705 204.660 1.00 87.28  ? 20   THR C CB  1 
ATOM   4908 O OG1 . THR B 2 20  ? 258.393 165.686 203.361 1.00 87.28  ? 20   THR C OG1 1 
ATOM   4909 C CG2 . THR B 2 20  ? 258.658 164.900 205.617 1.00 87.28  ? 20   THR C CG2 1 
ATOM   4910 N N   . ARG B 2 21  ? 254.238 165.193 205.699 1.00 82.90  ? 21   ARG C N   1 
ATOM   4911 C CA  . ARG B 2 21  ? 253.276 165.502 206.756 1.00 82.90  ? 21   ARG C CA  1 
ATOM   4912 C C   . ARG B 2 21  ? 252.586 164.199 207.145 1.00 82.90  ? 21   ARG C C   1 
ATOM   4913 O O   . ARG B 2 21  ? 251.635 163.770 206.483 1.00 82.90  ? 21   ARG C O   1 
ATOM   4914 C CB  . ARG B 2 21  ? 252.271 166.555 206.299 1.00 82.90  ? 21   ARG C CB  1 
ATOM   4915 C CG  . ARG B 2 21  ? 251.232 166.919 207.347 1.00 82.90  ? 21   ARG C CG  1 
ATOM   4916 C CD  . ARG B 2 21  ? 250.408 168.121 206.914 1.00 82.90  ? 21   ARG C CD  1 
ATOM   4917 N NE  . ARG B 2 21  ? 249.730 167.897 205.641 1.00 82.90  ? 21   ARG C NE  1 
ATOM   4918 C CZ  . ARG B 2 21  ? 248.962 168.797 205.036 1.00 82.90  ? 21   ARG C CZ  1 
ATOM   4919 N NH1 . ARG B 2 21  ? 248.384 168.508 203.879 1.00 82.90  ? 21   ARG C NH1 1 
ATOM   4920 N NH2 . ARG B 2 21  ? 248.772 169.987 205.588 1.00 82.90  ? 21   ARG C NH2 1 
ATOM   4921 N N   . THR B 2 22  ? 253.069 163.571 208.213 1.00 87.00  ? 22   THR C N   1 
ATOM   4922 C CA  . THR B 2 22  ? 252.516 162.296 208.648 1.00 87.00  ? 22   THR C CA  1 
ATOM   4923 C C   . THR B 2 22  ? 251.122 162.495 209.229 1.00 87.00  ? 22   THR C C   1 
ATOM   4924 O O   . THR B 2 22  ? 250.901 163.386 210.055 1.00 87.00  ? 22   THR C O   1 
ATOM   4925 C CB  . THR B 2 22  ? 253.434 161.645 209.682 1.00 87.00  ? 22   THR C CB  1 
ATOM   4926 O OG1 . THR B 2 22  ? 254.751 161.506 209.135 1.00 87.00  ? 22   THR C OG1 1 
ATOM   4927 C CG2 . THR B 2 22  ? 252.908 160.272 210.075 1.00 87.00  ? 22   THR C CG2 1 
ATOM   4928 N N   . GLN B 2 23  ? 250.180 161.663 208.794 1.00 89.15  ? 23   GLN C N   1 
ATOM   4929 C CA  . GLN B 2 23  ? 248.805 161.762 209.259 1.00 89.15  ? 23   GLN C CA  1 
ATOM   4930 C C   . GLN B 2 23  ? 248.659 161.131 210.637 1.00 89.15  ? 23   GLN C C   1 
ATOM   4931 O O   . GLN B 2 23  ? 249.207 160.059 210.909 1.00 89.15  ? 23   GLN C O   1 
ATOM   4932 C CB  . GLN B 2 23  ? 247.851 161.087 208.271 1.00 89.15  ? 23   GLN C CB  1 
ATOM   4933 C CG  . GLN B 2 23  ? 247.745 161.780 206.919 1.00 89.15  ? 23   GLN C CG  1 
ATOM   4934 C CD  . GLN B 2 23  ? 248.900 161.451 205.993 1.00 89.15  ? 23   GLN C CD  1 
ATOM   4935 O OE1 . GLN B 2 23  ? 249.221 162.219 205.085 1.00 89.15  ? 23   GLN C OE1 1 
ATOM   4936 N NE2 . GLN B 2 23  ? 249.528 160.302 206.213 1.00 89.15  ? 23   GLN C NE2 1 
ATOM   4937 N N   . LEU B 2 24  ? 247.915 161.806 211.506 1.00 87.20  ? 24   LEU C N   1 
ATOM   4938 C CA  . LEU B 2 24  ? 247.644 161.342 212.855 1.00 87.20  ? 24   LEU C CA  1 
ATOM   4939 C C   . LEU B 2 24  ? 246.148 161.397 213.121 1.00 87.20  ? 24   LEU C C   1 
ATOM   4940 O O   . LEU B 2 24  ? 245.444 162.234 212.546 1.00 87.20  ? 24   LEU C O   1 
ATOM   4941 C CB  . LEU B 2 24  ? 248.387 162.198 213.893 1.00 87.20  ? 24   LEU C CB  1 
ATOM   4942 C CG  . LEU B 2 24  ? 249.208 161.445 214.942 1.00 87.20  ? 24   LEU C CG  1 
ATOM   4943 C CD1 . LEU B 2 24  ? 250.273 160.588 214.275 1.00 87.20  ? 24   LEU C CD1 1 
ATOM   4944 C CD2 . LEU B 2 24  ? 249.836 162.411 215.934 1.00 87.20  ? 24   LEU C CD2 1 
ATOM   4945 N N   . PRO B 2 25  ? 245.633 160.512 213.971 1.00 85.14  ? 25   PRO C N   1 
ATOM   4946 C CA  . PRO B 2 25  ? 244.202 160.535 214.294 1.00 85.14  ? 25   PRO C CA  1 
ATOM   4947 C C   . PRO B 2 25  ? 243.806 161.857 214.925 1.00 85.14  ? 25   PRO C C   1 
ATOM   4948 O O   . PRO B 2 25  ? 244.510 162.371 215.807 1.00 85.14  ? 25   PRO C O   1 
ATOM   4949 C CB  . PRO B 2 25  ? 244.045 159.374 215.288 1.00 85.14  ? 25   PRO C CB  1 
ATOM   4950 C CG  . PRO B 2 25  ? 245.178 158.460 214.974 1.00 85.14  ? 25   PRO C CG  1 
ATOM   4951 C CD  . PRO B 2 25  ? 246.315 159.353 214.571 1.00 85.14  ? 25   PRO C CD  1 
ATOM   4952 N N   . PRO B 2 26  ? 242.688 162.442 214.496 1.00 80.36  ? 26   PRO C N   1 
ATOM   4953 C CA  . PRO B 2 26  ? 242.274 163.739 215.049 1.00 80.36  ? 26   PRO C CA  1 
ATOM   4954 C C   . PRO B 2 26  ? 241.831 163.600 216.498 1.00 80.36  ? 26   PRO C C   1 
ATOM   4955 O O   . PRO B 2 26  ? 241.060 162.702 216.845 1.00 80.36  ? 26   PRO C O   1 
ATOM   4956 C CB  . PRO B 2 26  ? 241.114 164.160 214.140 1.00 80.36  ? 26   PRO C CB  1 
ATOM   4957 C CG  . PRO B 2 26  ? 240.569 162.871 213.617 1.00 80.36  ? 26   PRO C CG  1 
ATOM   4958 C CD  . PRO B 2 26  ? 241.750 161.950 213.472 1.00 80.36  ? 26   PRO C CD  1 
ATOM   4959 N N   . ALA B 2 27  ? 242.326 164.497 217.343 1.00 75.93  ? 27   ALA C N   1 
ATOM   4960 C CA  . ALA B 2 27  ? 241.997 164.490 218.758 1.00 75.93  ? 27   ALA C CA  1 
ATOM   4961 C C   . ALA B 2 27  ? 240.784 165.372 219.033 1.00 75.93  ? 27   ALA C C   1 
ATOM   4962 O O   . ALA B 2 27  ? 240.416 166.237 218.235 1.00 75.93  ? 27   ALA C O   1 
ATOM   4963 C CB  . ALA B 2 27  ? 243.189 164.960 219.593 1.00 75.93  ? 27   ALA C CB  1 
ATOM   4964 N N   . TYR B 2 28  ? 240.163 165.140 220.187 1.00 78.20  ? 28   TYR C N   1 
ATOM   4965 C CA  . TYR B 2 28  ? 238.997 165.895 220.619 1.00 78.20  ? 28   TYR C CA  1 
ATOM   4966 C C   . TYR B 2 28  ? 239.187 166.330 222.064 1.00 78.20  ? 28   TYR C C   1 
ATOM   4967 O O   . TYR B 2 28  ? 239.714 165.573 222.885 1.00 78.20  ? 28   TYR C O   1 
ATOM   4968 C CB  . TYR B 2 28  ? 237.712 165.069 220.482 1.00 78.20  ? 28   TYR C CB  1 
ATOM   4969 C CG  . TYR B 2 28  ? 237.409 164.633 219.066 1.00 78.20  ? 28   TYR C CG  1 
ATOM   4970 C CD1 . TYR B 2 28  ? 236.601 165.403 218.241 1.00 78.20  ? 28   TYR C CD1 1 
ATOM   4971 C CD2 . TYR B 2 28  ? 237.931 163.452 218.555 1.00 78.20  ? 28   TYR C CD2 1 
ATOM   4972 C CE1 . TYR B 2 28  ? 236.320 165.009 216.947 1.00 78.20  ? 28   TYR C CE1 1 
ATOM   4973 C CE2 . TYR B 2 28  ? 237.656 163.051 217.262 1.00 78.20  ? 28   TYR C CE2 1 
ATOM   4974 C CZ  . TYR B 2 28  ? 236.850 163.833 216.463 1.00 78.20  ? 28   TYR C CZ  1 
ATOM   4975 O OH  . TYR B 2 28  ? 236.574 163.437 215.175 1.00 78.20  ? 28   TYR C OH  1 
ATOM   4976 N N   . THR B 2 29  ? 238.755 167.551 222.369 1.00 75.48  ? 29   THR C N   1 
ATOM   4977 C CA  . THR B 2 29  ? 238.904 168.126 223.699 1.00 75.48  ? 29   THR C CA  1 
ATOM   4978 C C   . THR B 2 29  ? 237.547 168.598 224.195 1.00 75.48  ? 29   THR C C   1 
ATOM   4979 O O   . THR B 2 29  ? 236.849 169.338 223.494 1.00 75.48  ? 29   THR C O   1 
ATOM   4980 C CB  . THR B 2 29  ? 239.898 169.293 223.692 1.00 75.48  ? 29   THR C CB  1 
ATOM   4981 O OG1 . THR B 2 29  ? 241.173 168.835 223.224 1.00 75.48  ? 29   THR C OG1 1 
ATOM   4982 C CG2 . THR B 2 29  ? 240.056 169.868 225.091 1.00 75.48  ? 29   THR C CG2 1 
ATOM   4983 N N   . ASN B 2 30  ? 237.177 168.169 225.399 1.00 76.90  ? 30   ASN C N   1 
ATOM   4984 C CA  . ASN B 2 30  ? 235.914 168.579 226.003 1.00 76.90  ? 30   ASN C CA  1 
ATOM   4985 C C   . ASN B 2 30  ? 235.989 170.055 226.370 1.00 76.90  ? 30   ASN C C   1 
ATOM   4986 O O   . ASN B 2 30  ? 236.728 170.440 227.282 1.00 76.90  ? 30   ASN C O   1 
ATOM   4987 C CB  . ASN B 2 30  ? 235.614 167.724 227.230 1.00 76.90  ? 30   ASN C CB  1 
ATOM   4988 C CG  . ASN B 2 30  ? 235.489 166.250 226.896 1.00 76.90  ? 30   ASN C CG  1 
ATOM   4989 O OD1 . ASN B 2 30  ? 235.074 165.884 225.797 1.00 76.90  ? 30   ASN C OD1 1 
ATOM   4990 N ND2 . ASN B 2 30  ? 235.850 165.396 227.847 1.00 76.90  ? 30   ASN C ND2 1 
ATOM   4991 N N   . SER B 2 31  ? 235.228 170.884 225.661 1.00 76.62  ? 31   SER C N   1 
ATOM   4992 C CA  . SER B 2 31  ? 235.242 172.315 225.923 1.00 76.62  ? 31   SER C CA  1 
ATOM   4993 C C   . SER B 2 31  ? 234.564 172.626 227.252 1.00 76.62  ? 31   SER C C   1 
ATOM   4994 O O   . SER B 2 31  ? 233.670 171.908 227.707 1.00 76.62  ? 31   SER C O   1 
ATOM   4995 C CB  . SER B 2 31  ? 234.545 173.075 224.795 1.00 76.62  ? 31   SER C CB  1 
ATOM   4996 O OG  . SER B 2 31  ? 233.180 172.709 224.700 1.00 76.62  ? 31   SER C OG  1 
ATOM   4997 N N   . PHE B 2 32  ? 235.009 173.710 227.876 1.00 75.13  ? 32   PHE C N   1 
ATOM   4998 C CA  . PHE B 2 32  ? 234.440 174.179 229.128 1.00 75.13  ? 32   PHE C CA  1 
ATOM   4999 C C   . PHE B 2 32  ? 233.329 175.186 228.832 1.00 75.13  ? 32   PHE C C   1 
ATOM   5000 O O   . PHE B 2 32  ? 232.845 175.294 227.702 1.00 75.13  ? 32   PHE C O   1 
ATOM   5001 C CB  . PHE B 2 32  ? 235.538 174.755 230.019 1.00 75.13  ? 32   PHE C CB  1 
ATOM   5002 C CG  . PHE B 2 32  ? 236.602 173.758 230.382 1.00 75.13  ? 32   PHE C CG  1 
ATOM   5003 C CD1 . PHE B 2 32  ? 236.374 172.809 231.364 1.00 75.13  ? 32   PHE C CD1 1 
ATOM   5004 C CD2 . PHE B 2 32  ? 237.828 173.767 229.739 1.00 75.13  ? 32   PHE C CD2 1 
ATOM   5005 C CE1 . PHE B 2 32  ? 237.349 171.890 231.700 1.00 75.13  ? 32   PHE C CE1 1 
ATOM   5006 C CE2 . PHE B 2 32  ? 238.808 172.850 230.071 1.00 75.13  ? 32   PHE C CE2 1 
ATOM   5007 C CZ  . PHE B 2 32  ? 238.568 171.911 231.052 1.00 75.13  ? 32   PHE C CZ  1 
ATOM   5008 N N   . THR B 2 33  ? 232.910 175.935 229.852 1.00 71.09  ? 33   THR C N   1 
ATOM   5009 C CA  . THR B 2 33  ? 231.790 176.863 229.732 1.00 71.09  ? 33   THR C CA  1 
ATOM   5010 C C   . THR B 2 33  ? 232.068 178.008 228.761 1.00 71.09  ? 33   THR C C   1 
ATOM   5011 O O   . THR B 2 33  ? 231.220 178.889 228.582 1.00 71.09  ? 33   THR C O   1 
ATOM   5012 C CB  . THR B 2 33  ? 231.428 177.432 231.105 1.00 71.09  ? 33   THR C CB  1 
ATOM   5013 O OG1 . THR B 2 33  ? 232.552 178.139 231.644 1.00 71.09  ? 33   THR C OG1 1 
ATOM   5014 C CG2 . THR B 2 33  ? 231.036 176.313 232.058 1.00 71.09  ? 33   THR C CG2 1 
ATOM   5015 N N   . ARG B 2 34  ? 233.244 178.014 228.138 1.00 69.16  ? 34   ARG C N   1 
ATOM   5016 C CA  . ARG B 2 34  ? 233.572 179.036 227.157 1.00 69.16  ? 34   ARG C CA  1 
ATOM   5017 C C   . ARG B 2 34  ? 232.662 178.927 225.935 1.00 69.16  ? 34   ARG C C   1 
ATOM   5018 O O   . ARG B 2 34  ? 232.068 177.883 225.655 1.00 69.16  ? 34   ARG C O   1 
ATOM   5019 C CB  . ARG B 2 34  ? 235.035 178.921 226.729 1.00 69.16  ? 34   ARG C CB  1 
ATOM   5020 C CG  . ARG B 2 34  ? 236.031 179.199 227.839 1.00 69.16  ? 34   ARG C CG  1 
ATOM   5021 C CD  . ARG B 2 34  ? 237.458 179.127 227.325 1.00 69.16  ? 34   ARG C CD  1 
ATOM   5022 N NE  . ARG B 2 34  ? 238.424 179.528 228.343 1.00 69.16  ? 34   ARG C NE  1 
ATOM   5023 C CZ  . ARG B 2 34  ? 238.822 180.780 228.542 1.00 69.16  ? 34   ARG C CZ  1 
ATOM   5024 N NH1 . ARG B 2 34  ? 239.705 181.055 229.491 1.00 69.16  ? 34   ARG C NH1 1 
ATOM   5025 N NH2 . ARG B 2 34  ? 238.335 181.758 227.790 1.00 69.16  ? 34   ARG C NH2 1 
ATOM   5026 N N   . GLY B 2 35  ? 232.562 180.034 225.201 1.00 63.90  ? 35   GLY C N   1 
ATOM   5027 C CA  . GLY B 2 35  ? 231.747 180.109 224.005 1.00 63.90  ? 35   GLY C CA  1 
ATOM   5028 C C   . GLY B 2 35  ? 230.574 181.058 224.100 1.00 63.90  ? 35   GLY C C   1 
ATOM   5029 O O   . GLY B 2 35  ? 229.901 181.285 223.087 1.00 63.90  ? 35   GLY C O   1 
ATOM   5030 N N   . VAL B 2 36  ? 230.306 181.619 225.274 1.00 62.57  ? 36   VAL C N   1 
ATOM   5031 C CA  . VAL B 2 36  ? 229.183 182.532 225.450 1.00 62.57  ? 36   VAL C CA  1 
ATOM   5032 C C   . VAL B 2 36  ? 229.560 183.906 224.916 1.00 62.57  ? 36   VAL C C   1 
ATOM   5033 O O   . VAL B 2 36  ? 230.658 184.412 225.176 1.00 62.57  ? 36   VAL C O   1 
ATOM   5034 C CB  . VAL B 2 36  ? 228.771 182.598 226.931 1.00 62.57  ? 36   VAL C CB  1 
ATOM   5035 C CG1 . VAL B 2 36  ? 227.572 183.515 227.111 1.00 62.57  ? 36   VAL C CG1 1 
ATOM   5036 C CG2 . VAL B 2 36  ? 228.468 181.205 227.459 1.00 62.57  ? 36   VAL C CG2 1 
ATOM   5037 N N   . TYR B 2 37  ? 228.649 184.514 224.162 1.00 60.17  ? 37   TYR C N   1 
ATOM   5038 C CA  . TYR B 2 37  ? 228.852 185.832 223.581 1.00 60.17  ? 37   TYR C CA  1 
ATOM   5039 C C   . TYR B 2 37  ? 227.637 186.702 223.879 1.00 60.17  ? 37   TYR C C   1 
ATOM   5040 O O   . TYR B 2 37  ? 226.671 186.265 224.512 1.00 60.17  ? 37   TYR C O   1 
ATOM   5041 C CB  . TYR B 2 37  ? 229.107 185.740 222.070 1.00 60.17  ? 37   TYR C CB  1 
ATOM   5042 C CG  . TYR B 2 37  ? 227.952 185.162 221.281 1.00 60.17  ? 37   TYR C CG  1 
ATOM   5043 C CD1 . TYR B 2 37  ? 227.801 183.789 221.137 1.00 60.17  ? 37   TYR C CD1 1 
ATOM   5044 C CD2 . TYR B 2 37  ? 227.017 185.990 220.675 1.00 60.17  ? 37   TYR C CD2 1 
ATOM   5045 C CE1 . TYR B 2 37  ? 226.749 183.258 220.416 1.00 60.17  ? 37   TYR C CE1 1 
ATOM   5046 C CE2 . TYR B 2 37  ? 225.962 185.468 219.952 1.00 60.17  ? 37   TYR C CE2 1 
ATOM   5047 C CZ  . TYR B 2 37  ? 225.833 184.102 219.826 1.00 60.17  ? 37   TYR C CZ  1 
ATOM   5048 O OH  . TYR B 2 37  ? 224.784 183.578 219.106 1.00 60.17  ? 37   TYR C OH  1 
ATOM   5049 N N   . TYR B 2 38  ? 227.691 187.952 223.418 1.00 61.70  ? 38   TYR C N   1 
ATOM   5050 C CA  . TYR B 2 38  ? 226.581 188.879 223.585 1.00 61.70  ? 38   TYR C CA  1 
ATOM   5051 C C   . TYR B 2 38  ? 225.611 188.702 222.425 1.00 61.70  ? 38   TYR C C   1 
ATOM   5052 O O   . TYR B 2 38  ? 225.960 189.045 221.285 1.00 61.70  ? 38   TYR C O   1 
ATOM   5053 C CB  . TYR B 2 38  ? 227.081 190.315 223.647 1.00 61.70  ? 38   TYR C CB  1 
ATOM   5054 C CG  . TYR B 2 38  ? 227.915 190.625 224.869 1.00 61.70  ? 38   TYR C CG  1 
ATOM   5055 C CD1 . TYR B 2 38  ? 227.318 191.029 226.056 1.00 61.70  ? 38   TYR C CD1 1 
ATOM   5056 C CD2 . TYR B 2 38  ? 229.299 190.519 224.836 1.00 61.70  ? 38   TYR C CD2 1 
ATOM   5057 C CE1 . TYR B 2 38  ? 228.074 191.316 227.175 1.00 61.70  ? 38   TYR C CE1 1 
ATOM   5058 C CE2 . TYR B 2 38  ? 230.064 190.804 225.951 1.00 61.70  ? 38   TYR C CE2 1 
ATOM   5059 C CZ  . TYR B 2 38  ? 229.447 191.202 227.117 1.00 61.70  ? 38   TYR C CZ  1 
ATOM   5060 O OH  . TYR B 2 38  ? 230.204 191.487 228.229 1.00 61.70  ? 38   TYR C OH  1 
ATOM   5061 N N   . PRO B 2 39  ? 224.403 188.181 222.653 1.00 61.82  ? 39   PRO C N   1 
ATOM   5062 C CA  . PRO B 2 39  ? 223.475 187.973 221.531 1.00 61.82  ? 39   PRO C CA  1 
ATOM   5063 C C   . PRO B 2 39  ? 222.883 189.258 220.984 1.00 61.82  ? 39   PRO C C   1 
ATOM   5064 O O   . PRO B 2 39  ? 222.427 189.266 219.834 1.00 61.82  ? 39   PRO C O   1 
ATOM   5065 C CB  . PRO B 2 39  ? 222.390 187.075 222.139 1.00 61.82  ? 39   PRO C CB  1 
ATOM   5066 C CG  . PRO B 2 39  ? 222.398 187.428 223.588 1.00 61.82  ? 39   PRO C CG  1 
ATOM   5067 C CD  . PRO B 2 39  ? 223.831 187.739 223.936 1.00 61.82  ? 39   PRO C CD  1 
ATOM   5068 N N   . ASP B 2 40  ? 222.874 190.339 221.760 1.00 64.23  ? 40   ASP C N   1 
ATOM   5069 C CA  . ASP B 2 40  ? 222.311 191.601 221.308 1.00 64.23  ? 40   ASP C CA  1 
ATOM   5070 C C   . ASP B 2 40  ? 223.121 192.746 221.898 1.00 64.23  ? 40   ASP C C   1 
ATOM   5071 O O   . ASP B 2 40  ? 224.028 192.543 222.709 1.00 64.23  ? 40   ASP C O   1 
ATOM   5072 C CB  . ASP B 2 40  ? 220.831 191.719 221.691 1.00 64.23  ? 40   ASP C CB  1 
ATOM   5073 C CG  . ASP B 2 40  ? 220.578 191.401 223.152 1.00 64.23  ? 40   ASP C CG  1 
ATOM   5074 O OD1 . ASP B 2 40  ? 221.542 191.049 223.863 1.00 64.23  ? 40   ASP C OD1 1 
ATOM   5075 O OD2 . ASP B 2 40  ? 219.412 191.499 223.589 1.00 64.23  ? 40   ASP C OD2 1 
ATOM   5076 N N   . LYS B 2 41  ? 222.780 193.964 221.476 1.00 62.54  ? 41   LYS C N   1 
ATOM   5077 C CA  . LYS B 2 41  ? 223.448 195.176 221.932 1.00 62.54  ? 41   LYS C CA  1 
ATOM   5078 C C   . LYS B 2 41  ? 222.662 195.892 223.025 1.00 62.54  ? 41   LYS C C   1 
ATOM   5079 O O   . LYS B 2 41  ? 222.672 197.126 223.093 1.00 62.54  ? 41   LYS C O   1 
ATOM   5080 C CB  . LYS B 2 41  ? 223.696 196.116 220.752 1.00 62.54  ? 41   LYS C CB  1 
ATOM   5081 C CG  . LYS B 2 41  ? 224.524 195.504 219.635 1.00 62.54  ? 41   LYS C CG  1 
ATOM   5082 C CD  . LYS B 2 41  ? 224.695 196.475 218.479 1.00 62.54  ? 41   LYS C CD  1 
ATOM   5083 C CE  . LYS B 2 41  ? 225.518 195.860 217.359 1.00 62.54  ? 41   LYS C CE  1 
ATOM   5084 N NZ  . LYS B 2 41  ? 226.884 195.487 217.814 1.00 62.54  ? 41   LYS C NZ  1 
ATOM   5085 N N   . VAL B 2 42  ? 221.981 195.139 223.883 1.00 65.87  ? 42   VAL C N   1 
ATOM   5086 C CA  . VAL B 2 42  ? 221.149 195.695 224.943 1.00 65.87  ? 42   VAL C CA  1 
ATOM   5087 C C   . VAL B 2 42  ? 221.945 195.716 226.239 1.00 65.87  ? 42   VAL C C   1 
ATOM   5088 O O   . VAL B 2 42  ? 222.650 194.753 226.566 1.00 65.87  ? 42   VAL C O   1 
ATOM   5089 C CB  . VAL B 2 42  ? 219.848 194.884 225.105 1.00 65.87  ? 42   VAL C CB  1 
ATOM   5090 C CG1 . VAL B 2 42  ? 218.960 195.506 226.167 1.00 65.87  ? 42   VAL C CG1 1 
ATOM   5091 C CG2 . VAL B 2 42  ? 219.114 194.794 223.776 1.00 65.87  ? 42   VAL C CG2 1 
ATOM   5092 N N   . PHE B 2 43  ? 221.837 196.818 226.978 1.00 66.28  ? 43   PHE C N   1 
ATOM   5093 C CA  . PHE B 2 43  ? 222.519 196.966 228.256 1.00 66.28  ? 43   PHE C CA  1 
ATOM   5094 C C   . PHE B 2 43  ? 221.625 196.465 229.383 1.00 66.28  ? 43   PHE C C   1 
ATOM   5095 O O   . PHE B 2 43  ? 220.486 196.918 229.529 1.00 66.28  ? 43   PHE C O   1 
ATOM   5096 C CB  . PHE B 2 43  ? 222.905 198.426 228.498 1.00 66.28  ? 43   PHE C CB  1 
ATOM   5097 C CG  . PHE B 2 43  ? 223.521 198.679 229.847 1.00 66.28  ? 43   PHE C CG  1 
ATOM   5098 C CD1 . PHE B 2 43  ? 222.748 199.127 230.907 1.00 66.28  ? 43   PHE C CD1 1 
ATOM   5099 C CD2 . PHE B 2 43  ? 224.875 198.473 230.055 1.00 66.28  ? 43   PHE C CD2 1 
ATOM   5100 C CE1 . PHE B 2 43  ? 223.313 199.362 232.146 1.00 66.28  ? 43   PHE C CE1 1 
ATOM   5101 C CE2 . PHE B 2 43  ? 225.445 198.706 231.292 1.00 66.28  ? 43   PHE C CE2 1 
ATOM   5102 C CZ  . PHE B 2 43  ? 224.663 199.151 232.338 1.00 66.28  ? 43   PHE C CZ  1 
ATOM   5103 N N   . ARG B 2 44  ? 222.146 195.531 230.174 1.00 66.46  ? 44   ARG C N   1 
ATOM   5104 C CA  . ARG B 2 44  ? 221.448 194.994 231.332 1.00 66.46  ? 44   ARG C CA  1 
ATOM   5105 C C   . ARG B 2 44  ? 222.404 194.959 232.514 1.00 66.46  ? 44   ARG C C   1 
ATOM   5106 O O   . ARG B 2 44  ? 223.595 194.679 232.349 1.00 66.46  ? 44   ARG C O   1 
ATOM   5107 C CB  . ARG B 2 44  ? 220.897 193.592 231.051 1.00 66.46  ? 44   ARG C CB  1 
ATOM   5108 C CG  . ARG B 2 44  ? 219.869 193.545 229.932 1.00 66.46  ? 44   ARG C CG  1 
ATOM   5109 C CD  . ARG B 2 44  ? 219.420 192.123 229.647 1.00 66.46  ? 44   ARG C CD  1 
ATOM   5110 N NE  . ARG B 2 44  ? 218.425 192.070 228.580 1.00 66.46  ? 44   ARG C NE  1 
ATOM   5111 C CZ  . ARG B 2 44  ? 218.721 191.989 227.287 1.00 66.46  ? 44   ARG C CZ  1 
ATOM   5112 N NH1 . ARG B 2 44  ? 217.750 191.945 226.385 1.00 66.46  ? 44   ARG C NH1 1 
ATOM   5113 N NH2 . ARG B 2 44  ? 219.986 191.952 226.895 1.00 66.46  ? 44   ARG C NH2 1 
ATOM   5114 N N   . SER B 2 45  ? 221.882 195.246 233.705 1.00 73.87  ? 45   SER C N   1 
ATOM   5115 C CA  . SER B 2 45  ? 222.703 195.330 234.907 1.00 73.87  ? 45   SER C CA  1 
ATOM   5116 C C   . SER B 2 45  ? 222.014 194.590 236.041 1.00 73.87  ? 45   SER C C   1 
ATOM   5117 O O   . SER B 2 45  ? 220.861 194.889 236.366 1.00 73.87  ? 45   SER C O   1 
ATOM   5118 C CB  . SER B 2 45  ? 222.960 196.789 235.298 1.00 73.87  ? 45   SER C CB  1 
ATOM   5119 O OG  . SER B 2 45  ? 221.744 197.469 235.556 1.00 73.87  ? 45   SER C OG  1 
ATOM   5120 N N   . SER B 2 46  ? 222.725 193.630 236.637 1.00 71.54  ? 46   SER C N   1 
ATOM   5121 C CA  . SER B 2 46  ? 222.247 192.886 237.804 1.00 71.54  ? 46   SER C CA  1 
ATOM   5122 C C   . SER B 2 46  ? 220.911 192.199 237.520 1.00 71.54  ? 46   SER C C   1 
ATOM   5123 O O   . SER B 2 46  ? 219.941 192.338 238.268 1.00 71.54  ? 46   SER C O   1 
ATOM   5124 C CB  . SER B 2 46  ? 222.147 193.798 239.029 1.00 71.54  ? 46   SER C CB  1 
ATOM   5125 O OG  . SER B 2 46  ? 223.399 194.391 239.326 1.00 71.54  ? 46   SER C OG  1 
ATOM   5126 N N   . VAL B 2 47  ? 220.868 191.445 236.421 1.00 68.92  ? 47   VAL C N   1 
ATOM   5127 C CA  . VAL B 2 47  ? 219.667 190.724 236.017 1.00 68.92  ? 47   VAL C CA  1 
ATOM   5128 C C   . VAL B 2 47  ? 220.091 189.442 235.314 1.00 68.92  ? 47   VAL C C   1 
ATOM   5129 O O   . VAL B 2 47  ? 221.217 189.317 234.827 1.00 68.92  ? 47   VAL C O   1 
ATOM   5130 C CB  . VAL B 2 47  ? 218.757 191.584 235.104 1.00 68.92  ? 47   VAL C CB  1 
ATOM   5131 C CG1 . VAL B 2 47  ? 219.293 191.612 233.681 1.00 68.92  ? 47   VAL C CG1 1 
ATOM   5132 C CG2 . VAL B 2 47  ? 217.318 191.082 235.142 1.00 68.92  ? 47   VAL C CG2 1 
ATOM   5133 N N   . LEU B 2 48  ? 219.177 188.477 235.274 1.00 67.68  ? 48   LEU C N   1 
ATOM   5134 C CA  . LEU B 2 48  ? 219.398 187.193 234.612 1.00 67.68  ? 48   LEU C CA  1 
ATOM   5135 C C   . LEU B 2 48  ? 218.437 187.111 233.431 1.00 67.68  ? 48   LEU C C   1 
ATOM   5136 O O   . LEU B 2 48  ? 217.240 186.864 233.608 1.00 67.68  ? 48   LEU C O   1 
ATOM   5137 C CB  . LEU B 2 48  ? 219.197 186.029 235.581 1.00 67.68  ? 48   LEU C CB  1 
ATOM   5138 C CG  . LEU B 2 48  ? 220.297 185.739 236.609 1.00 67.68  ? 48   LEU C CG  1 
ATOM   5139 C CD1 . LEU B 2 48  ? 220.307 186.762 237.736 1.00 67.68  ? 48   LEU C CD1 1 
ATOM   5140 C CD2 . LEU B 2 48  ? 220.147 184.330 237.164 1.00 67.68  ? 48   LEU C CD2 1 
ATOM   5141 N N   . HIS B 2 49  ? 218.963 187.319 232.229 1.00 68.78  ? 49   HIS C N   1 
ATOM   5142 C CA  . HIS B 2 49  ? 218.165 187.318 231.012 1.00 68.78  ? 49   HIS C CA  1 
ATOM   5143 C C   . HIS B 2 49  ? 218.273 185.969 230.315 1.00 68.78  ? 49   HIS C C   1 
ATOM   5144 O O   . HIS B 2 49  ? 219.340 185.348 230.301 1.00 68.78  ? 49   HIS C O   1 
ATOM   5145 C CB  . HIS B 2 49  ? 218.614 188.434 230.067 1.00 68.78  ? 49   HIS C CB  1 
ATOM   5146 C CG  . HIS B 2 49  ? 217.722 188.617 228.880 1.00 68.78  ? 49   HIS C CG  1 
ATOM   5147 N ND1 . HIS B 2 49  ? 216.382 188.915 228.995 1.00 68.78  ? 49   HIS C ND1 1 
ATOM   5148 C CD2 . HIS B 2 49  ? 217.979 188.548 227.552 1.00 68.78  ? 49   HIS C CD2 1 
ATOM   5149 C CE1 . HIS B 2 49  ? 215.851 189.019 227.790 1.00 68.78  ? 49   HIS C CE1 1 
ATOM   5150 N NE2 . HIS B 2 49  ? 216.799 188.802 226.897 1.00 68.78  ? 49   HIS C NE2 1 
ATOM   5151 N N   . SER B 2 50  ? 217.163 185.521 229.735 1.00 65.25  ? 50   SER C N   1 
ATOM   5152 C CA  . SER B 2 50  ? 217.089 184.243 229.038 1.00 65.25  ? 50   SER C CA  1 
ATOM   5153 C C   . SER B 2 50  ? 217.067 184.498 227.538 1.00 65.25  ? 50   SER C C   1 
ATOM   5154 O O   . SER B 2 50  ? 216.211 185.240 227.044 1.00 65.25  ? 50   SER C O   1 
ATOM   5155 C CB  . SER B 2 50  ? 215.852 183.455 229.470 1.00 65.25  ? 50   SER C CB  1 
ATOM   5156 O OG  . SER B 2 50  ? 215.779 182.211 228.796 1.00 65.25  ? 50   SER C OG  1 
ATOM   5157 N N   . THR B 2 51  ? 218.003 183.885 226.819 1.00 65.25  ? 51   THR C N   1 
ATOM   5158 C CA  . THR B 2 51  ? 218.127 184.050 225.380 1.00 65.25  ? 51   THR C CA  1 
ATOM   5159 C C   . THR B 2 51  ? 218.014 182.700 224.686 1.00 65.25  ? 51   THR C C   1 
ATOM   5160 O O   . THR B 2 51  ? 218.458 181.674 225.209 1.00 65.25  ? 51   THR C O   1 
ATOM   5161 C CB  . THR B 2 51  ? 219.460 184.710 225.003 1.00 65.25  ? 51   THR C CB  1 
ATOM   5162 O OG1 . THR B 2 51  ? 220.545 183.891 225.456 1.00 65.25  ? 51   THR C OG1 1 
ATOM   5163 C CG2 . THR B 2 51  ? 219.573 186.086 225.638 1.00 65.25  ? 51   THR C CG2 1 
ATOM   5164 N N   . GLN B 2 52  ? 217.411 182.712 223.496 1.00 69.09  ? 52   GLN C N   1 
ATOM   5165 C CA  . GLN B 2 52  ? 217.257 181.519 222.662 1.00 69.09  ? 52   GLN C CA  1 
ATOM   5166 C C   . GLN B 2 52  ? 217.857 181.843 221.296 1.00 69.09  ? 52   GLN C C   1 
ATOM   5167 O O   . GLN B 2 52  ? 217.152 182.296 220.390 1.00 69.09  ? 52   GLN C O   1 
ATOM   5168 C CB  . GLN B 2 52  ? 215.793 181.096 222.552 1.00 69.09  ? 52   GLN C CB  1 
ATOM   5169 C CG  . GLN B 2 52  ? 215.161 180.653 223.865 1.00 69.09  ? 52   GLN C CG  1 
ATOM   5170 C CD  . GLN B 2 52  ? 214.717 181.818 224.729 1.00 69.09  ? 52   GLN C CD  1 
ATOM   5171 O OE1 . GLN B 2 52  ? 214.577 181.686 225.945 1.00 69.09  ? 52   GLN C OE1 1 
ATOM   5172 N NE2 . GLN B 2 52  ? 214.487 182.967 224.103 1.00 69.09  ? 52   GLN C NE2 1 
ATOM   5173 N N   . ASP B 2 53  ? 219.160 181.608 221.152 1.00 64.90  ? 53   ASP C N   1 
ATOM   5174 C CA  . ASP B 2 53  ? 219.874 181.897 219.917 1.00 64.90  ? 53   ASP C CA  1 
ATOM   5175 C C   . ASP B 2 53  ? 220.916 180.808 219.694 1.00 64.90  ? 53   ASP C C   1 
ATOM   5176 O O   . ASP B 2 53  ? 221.011 179.844 220.460 1.00 64.90  ? 53   ASP C O   1 
ATOM   5177 C CB  . ASP B 2 53  ? 220.510 183.293 219.967 1.00 64.90  ? 53   ASP C CB  1 
ATOM   5178 C CG  . ASP B 2 53  ? 220.792 183.858 218.588 1.00 64.90  ? 53   ASP C CG  1 
ATOM   5179 O OD1 . ASP B 2 53  ? 220.514 183.161 217.590 1.00 64.90  ? 53   ASP C OD1 1 
ATOM   5180 O OD2 . ASP B 2 53  ? 221.290 185.000 218.503 1.00 64.90  ? 53   ASP C OD2 1 
ATOM   5181 N N   . LEU B 2 54  ? 221.699 180.961 218.630 1.00 62.65  ? 54   LEU C N   1 
ATOM   5182 C CA  . LEU B 2 54  ? 222.748 180.001 218.293 1.00 62.65  ? 54   LEU C CA  1 
ATOM   5183 C C   . LEU B 2 54  ? 223.905 180.168 219.269 1.00 62.65  ? 54   LEU C C   1 
ATOM   5184 O O   . LEU B 2 54  ? 224.682 181.120 219.175 1.00 62.65  ? 54   LEU C O   1 
ATOM   5185 C CB  . LEU B 2 54  ? 223.210 180.204 216.854 1.00 62.65  ? 54   LEU C CB  1 
ATOM   5186 C CG  . LEU B 2 54  ? 222.133 180.116 215.771 1.00 62.65  ? 54   LEU C CG  1 
ATOM   5187 C CD1 . LEU B 2 54  ? 222.733 180.372 214.398 1.00 62.65  ? 54   LEU C CD1 1 
ATOM   5188 C CD2 . LEU B 2 54  ? 221.443 178.765 215.812 1.00 62.65  ? 54   LEU C CD2 1 
ATOM   5189 N N   . PHE B 2 55  ? 224.024 179.241 220.211 1.00 61.63  ? 55   PHE C N   1 
ATOM   5190 C CA  . PHE B 2 55  ? 225.084 179.250 221.209 1.00 61.63  ? 55   PHE C CA  1 
ATOM   5191 C C   . PHE B 2 55  ? 225.843 177.927 221.168 1.00 61.63  ? 55   PHE C C   1 
ATOM   5192 O O   . PHE B 2 55  ? 225.517 177.016 220.404 1.00 61.63  ? 55   PHE C O   1 
ATOM   5193 C CB  . PHE B 2 55  ? 224.520 179.505 222.610 1.00 61.63  ? 55   PHE C CB  1 
ATOM   5194 C CG  . PHE B 2 55  ? 224.042 180.911 222.829 1.00 61.63  ? 55   PHE C CG  1 
ATOM   5195 C CD1 . PHE B 2 55  ? 224.939 181.921 223.130 1.00 61.63  ? 55   PHE C CD1 1 
ATOM   5196 C CD2 . PHE B 2 55  ? 222.695 181.220 222.748 1.00 61.63  ? 55   PHE C CD2 1 
ATOM   5197 C CE1 . PHE B 2 55  ? 224.503 183.215 223.337 1.00 61.63  ? 55   PHE C CE1 1 
ATOM   5198 C CE2 . PHE B 2 55  ? 222.253 182.512 222.955 1.00 61.63  ? 55   PHE C CE2 1 
ATOM   5199 C CZ  . PHE B 2 55  ? 223.159 183.511 223.249 1.00 61.63  ? 55   PHE C CZ  1 
ATOM   5200 N N   . LEU B 2 56  ? 226.870 177.833 222.010 1.00 64.38  ? 56   LEU C N   1 
ATOM   5201 C CA  . LEU B 2 56  ? 227.677 176.632 222.140 1.00 64.38  ? 56   LEU C CA  1 
ATOM   5202 C C   . LEU B 2 56  ? 227.410 175.978 223.485 1.00 64.38  ? 56   LEU C C   1 
ATOM   5203 O O   . LEU B 2 56  ? 227.423 176.669 224.513 1.00 64.38  ? 56   LEU C O   1 
ATOM   5204 C CB  . LEU B 2 56  ? 229.168 176.967 222.011 1.00 64.38  ? 56   LEU C CB  1 
ATOM   5205 C CG  . LEU B 2 56  ? 230.159 175.806 222.122 1.00 64.38  ? 56   LEU C CG  1 
ATOM   5206 C CD1 . LEU B 2 56  ? 230.064 174.893 220.911 1.00 64.38  ? 56   LEU C CD1 1 
ATOM   5207 C CD2 . LEU B 2 56  ? 231.578 176.325 222.295 1.00 64.38  ? 56   LEU C CD2 1 
ATOM   5208 N N   . PRO B 2 57  ? 227.154 174.671 223.524 1.00 67.50  ? 57   PRO C N   1 
ATOM   5209 C CA  . PRO B 2 57  ? 226.928 174.003 224.810 1.00 67.50  ? 57   PRO C CA  1 
ATOM   5210 C C   . PRO B 2 57  ? 228.158 174.077 225.703 1.00 67.50  ? 57   PRO C C   1 
ATOM   5211 O O   . PRO B 2 57  ? 229.285 174.276 225.246 1.00 67.50  ? 57   PRO C O   1 
ATOM   5212 C CB  . PRO B 2 57  ? 226.615 172.556 224.410 1.00 67.50  ? 57   PRO C CB  1 
ATOM   5213 C CG  . PRO B 2 57  ? 226.149 172.645 222.994 1.00 67.50  ? 57   PRO C CG  1 
ATOM   5214 C CD  . PRO B 2 57  ? 226.932 173.768 222.383 1.00 67.50  ? 57   PRO C CD  1 
ATOM   5215 N N   . PHE B 2 58  ? 227.922 173.910 227.006 1.00 71.41  ? 58   PHE C N   1 
ATOM   5216 C CA  . PHE B 2 58  ? 229.007 174.037 227.973 1.00 71.41  ? 58   PHE C CA  1 
ATOM   5217 C C   . PHE B 2 58  ? 229.984 172.871 227.893 1.00 71.41  ? 58   PHE C C   1 
ATOM   5218 O O   . PHE B 2 58  ? 231.155 173.024 228.259 1.00 71.41  ? 58   PHE C O   1 
ATOM   5219 C CB  . PHE B 2 58  ? 228.442 174.155 229.388 1.00 71.41  ? 58   PHE C CB  1 
ATOM   5220 C CG  . PHE B 2 58  ? 227.872 175.507 229.702 1.00 71.41  ? 58   PHE C CG  1 
ATOM   5221 C CD1 . PHE B 2 58  ? 226.989 175.674 230.755 1.00 71.41  ? 58   PHE C CD1 1 
ATOM   5222 C CD2 . PHE B 2 58  ? 228.224 176.614 228.948 1.00 71.41  ? 58   PHE C CD2 1 
ATOM   5223 C CE1 . PHE B 2 58  ? 226.465 176.918 231.047 1.00 71.41  ? 58   PHE C CE1 1 
ATOM   5224 C CE2 . PHE B 2 58  ? 227.704 177.860 229.236 1.00 71.41  ? 58   PHE C CE2 1 
ATOM   5225 C CZ  . PHE B 2 58  ? 226.823 178.012 230.286 1.00 71.41  ? 58   PHE C CZ  1 
ATOM   5226 N N   . PHE B 2 59  ? 229.533 171.708 227.428 1.00 72.60  ? 59   PHE C N   1 
ATOM   5227 C CA  . PHE B 2 59  ? 230.388 170.528 227.330 1.00 72.60  ? 59   PHE C CA  1 
ATOM   5228 C C   . PHE B 2 59  ? 230.002 169.758 226.075 1.00 72.60  ? 59   PHE C C   1 
ATOM   5229 O O   . PHE B 2 59  ? 228.939 169.130 226.032 1.00 72.60  ? 59   PHE C O   1 
ATOM   5230 C CB  . PHE B 2 59  ? 230.262 169.645 228.573 1.00 72.60  ? 59   PHE C CB  1 
ATOM   5231 C CG  . PHE B 2 59  ? 230.730 170.308 229.838 1.00 72.60  ? 59   PHE C CG  1 
ATOM   5232 C CD1 . PHE B 2 59  ? 232.068 170.287 230.192 1.00 72.60  ? 59   PHE C CD1 1 
ATOM   5233 C CD2 . PHE B 2 59  ? 229.831 170.950 230.673 1.00 72.60  ? 59   PHE C CD2 1 
ATOM   5234 C CE1 . PHE B 2 59  ? 232.501 170.895 231.355 1.00 72.60  ? 59   PHE C CE1 1 
ATOM   5235 C CE2 . PHE B 2 59  ? 230.259 171.560 231.837 1.00 72.60  ? 59   PHE C CE2 1 
ATOM   5236 C CZ  . PHE B 2 59  ? 231.595 171.532 232.178 1.00 72.60  ? 59   PHE C CZ  1 
ATOM   5237 N N   . SER B 2 60  ? 230.860 169.807 225.060 1.00 75.61  ? 60   SER C N   1 
ATOM   5238 C CA  . SER B 2 60  ? 230.614 169.102 223.811 1.00 75.61  ? 60   SER C CA  1 
ATOM   5239 C C   . SER B 2 60  ? 231.948 168.744 223.174 1.00 75.61  ? 60   SER C C   1 
ATOM   5240 O O   . SER B 2 60  ? 233.003 169.255 223.558 1.00 75.61  ? 60   SER C O   1 
ATOM   5241 C CB  . SER B 2 60  ? 229.761 169.939 222.852 1.00 75.61  ? 60   SER C CB  1 
ATOM   5242 O OG  . SER B 2 60  ? 228.463 170.149 223.377 1.00 75.61  ? 60   SER C OG  1 
ATOM   5243 N N   . ASN B 2 61  ? 231.889 167.849 222.191 1.00 82.92  ? 61   ASN C N   1 
ATOM   5244 C CA  . ASN B 2 61  ? 233.083 167.455 221.454 1.00 82.92  ? 61   ASN C CA  1 
ATOM   5245 C C   . ASN B 2 61  ? 233.580 168.621 220.611 1.00 82.92  ? 61   ASN C C   1 
ATOM   5246 O O   . ASN B 2 61  ? 232.840 169.156 219.779 1.00 82.92  ? 61   ASN C O   1 
ATOM   5247 C CB  . ASN B 2 61  ? 232.789 166.250 220.564 1.00 82.92  ? 61   ASN C CB  1 
ATOM   5248 C CG  . ASN B 2 61  ? 232.729 164.947 221.335 1.00 82.92  ? 61   ASN C CG  1 
ATOM   5249 O OD1 . ASN B 2 61  ? 232.107 164.860 222.394 1.00 82.92  ? 61   ASN C OD1 1 
ATOM   5250 N ND2 . ASN B 2 61  ? 233.387 163.922 220.797 1.00 82.92  ? 61   ASN C ND2 1 
ATOM   5251 N N   . VAL B 2 62  ? 234.832 169.014 220.824 1.00 72.69  ? 62   VAL C N   1 
ATOM   5252 C CA  . VAL B 2 62  ? 235.485 170.051 220.035 1.00 72.69  ? 62   VAL C CA  1 
ATOM   5253 C C   . VAL B 2 62  ? 236.728 169.438 219.408 1.00 72.69  ? 62   VAL C C   1 
ATOM   5254 O O   . VAL B 2 62  ? 237.582 168.892 220.117 1.00 72.69  ? 62   VAL C O   1 
ATOM   5255 C CB  . VAL B 2 62  ? 235.841 171.280 220.884 1.00 72.69  ? 62   VAL C CB  1 
ATOM   5256 C CG1 . VAL B 2 62  ? 236.676 172.255 220.077 1.00 72.69  ? 62   VAL C CG1 1 
ATOM   5257 C CG2 . VAL B 2 62  ? 234.576 171.954 221.384 1.00 72.69  ? 62   VAL C CG2 1 
ATOM   5258 N N   . THR B 2 63  ? 236.828 169.526 218.084 1.00 71.59  ? 63   THR C N   1 
ATOM   5259 C CA  . THR B 2 63  ? 237.933 168.895 217.376 1.00 71.59  ? 63   THR C CA  1 
ATOM   5260 C C   . THR B 2 63  ? 239.228 169.656 217.630 1.00 71.59  ? 63   THR C C   1 
ATOM   5261 O O   . THR B 2 63  ? 239.303 170.869 217.414 1.00 71.59  ? 63   THR C O   1 
ATOM   5262 C CB  . THR B 2 63  ? 237.640 168.832 215.879 1.00 71.59  ? 63   THR C CB  1 
ATOM   5263 O OG1 . THR B 2 63  ? 236.301 168.366 215.673 1.00 71.59  ? 63   THR C OG1 1 
ATOM   5264 C CG2 . THR B 2 63  ? 238.605 167.879 215.194 1.00 71.59  ? 63   THR C CG2 1 
ATOM   5265 N N   . TRP B 2 64  ? 240.248 168.937 218.089 1.00 74.58  ? 64   TRP C N   1 
ATOM   5266 C CA  . TRP B 2 64  ? 241.545 169.517 218.411 1.00 74.58  ? 64   TRP C CA  1 
ATOM   5267 C C   . TRP B 2 64  ? 242.486 169.311 217.230 1.00 74.58  ? 64   TRP C C   1 
ATOM   5268 O O   . TRP B 2 64  ? 242.745 168.172 216.830 1.00 74.58  ? 64   TRP C O   1 
ATOM   5269 C CB  . TRP B 2 64  ? 242.119 168.883 219.677 1.00 74.58  ? 64   TRP C CB  1 
ATOM   5270 C CG  . TRP B 2 64  ? 243.339 169.568 220.208 1.00 74.58  ? 64   TRP C CG  1 
ATOM   5271 C CD1 . TRP B 2 64  ? 243.865 170.754 219.785 1.00 74.58  ? 64   TRP C CD1 1 
ATOM   5272 C CD2 . TRP B 2 64  ? 244.188 169.106 221.264 1.00 74.58  ? 64   TRP C CD2 1 
ATOM   5273 N NE1 . TRP B 2 64  ? 244.989 171.059 220.513 1.00 74.58  ? 64   TRP C NE1 1 
ATOM   5274 C CE2 . TRP B 2 64  ? 245.209 170.063 221.428 1.00 74.58  ? 64   TRP C CE2 1 
ATOM   5275 C CE3 . TRP B 2 64  ? 244.184 167.976 222.087 1.00 74.58  ? 64   TRP C CE3 1 
ATOM   5276 C CZ2 . TRP B 2 64  ? 246.215 169.925 222.381 1.00 74.58  ? 64   TRP C CZ2 1 
ATOM   5277 C CZ3 . TRP B 2 64  ? 245.184 167.841 223.032 1.00 74.58  ? 64   TRP C CZ3 1 
ATOM   5278 C CH2 . TRP B 2 64  ? 246.185 168.810 223.171 1.00 74.58  ? 64   TRP C CH2 1 
ATOM   5279 N N   . PHE B 2 65  ? 242.993 170.410 216.680 1.00 70.30  ? 65   PHE C N   1 
ATOM   5280 C CA  . PHE B 2 65  ? 243.909 170.377 215.547 1.00 70.30  ? 65   PHE C CA  1 
ATOM   5281 C C   . PHE B 2 65  ? 245.296 170.788 216.019 1.00 70.30  ? 65   PHE C C   1 
ATOM   5282 O O   . PHE B 2 65  ? 245.464 171.864 216.604 1.00 70.30  ? 65   PHE C O   1 
ATOM   5283 C CB  . PHE B 2 65  ? 243.424 171.293 214.424 1.00 70.30  ? 65   PHE C CB  1 
ATOM   5284 C CG  . PHE B 2 65  ? 242.126 170.858 213.810 1.00 70.30  ? 65   PHE C CG  1 
ATOM   5285 C CD1 . PHE B 2 65  ? 242.108 169.920 212.792 1.00 70.30  ? 65   PHE C CD1 1 
ATOM   5286 C CD2 . PHE B 2 65  ? 240.924 171.383 214.252 1.00 70.30  ? 65   PHE C CD2 1 
ATOM   5287 C CE1 . PHE B 2 65  ? 240.917 169.516 212.226 1.00 70.30  ? 65   PHE C CE1 1 
ATOM   5288 C CE2 . PHE B 2 65  ? 239.729 170.983 213.688 1.00 70.30  ? 65   PHE C CE2 1 
ATOM   5289 C CZ  . PHE B 2 65  ? 239.727 170.048 212.673 1.00 70.30  ? 65   PHE C CZ  1 
ATOM   5290 N N   . HIS B 2 66  ? 246.282 169.935 215.764 1.00 77.42  ? 66   HIS C N   1 
ATOM   5291 C CA  . HIS B 2 66  ? 247.652 170.163 216.192 1.00 77.42  ? 66   HIS C CA  1 
ATOM   5292 C C   . HIS B 2 66  ? 248.487 170.725 215.049 1.00 77.42  ? 66   HIS C C   1 
ATOM   5293 O O   . HIS B 2 66  ? 248.287 170.386 213.880 1.00 77.42  ? 66   HIS C O   1 
ATOM   5294 C CB  . HIS B 2 66  ? 248.287 168.868 216.703 1.00 77.42  ? 66   HIS C CB  1 
ATOM   5295 C CG  . HIS B 2 66  ? 247.613 168.297 217.911 1.00 77.42  ? 66   HIS C CG  1 
ATOM   5296 N ND1 . HIS B 2 66  ? 248.162 168.368 219.172 1.00 77.42  ? 66   HIS C ND1 1 
ATOM   5297 C CD2 . HIS B 2 66  ? 246.434 167.645 218.049 1.00 77.42  ? 66   HIS C CD2 1 
ATOM   5298 C CE1 . HIS B 2 66  ? 247.352 167.784 220.037 1.00 77.42  ? 66   HIS C CE1 1 
ATOM   5299 N NE2 . HIS B 2 66  ? 246.296 167.337 219.381 1.00 77.42  ? 66   HIS C NE2 1 
ATOM   5300 N N   . ALA B 2 67  ? 249.431 171.597 215.405 1.00 78.04  ? 67   ALA C N   1 
ATOM   5301 C CA  . ALA B 2 67  ? 250.411 172.142 214.461 1.00 78.04  ? 67   ALA C CA  1 
ATOM   5302 C C   . ALA B 2 67  ? 251.735 172.241 215.215 1.00 78.04  ? 67   ALA C C   1 
ATOM   5303 O O   . ALA B 2 67  ? 252.012 173.246 215.875 1.00 78.04  ? 67   ALA C O   1 
ATOM   5304 C CB  . ALA B 2 67  ? 249.968 173.489 213.905 1.00 78.04  ? 67   ALA C CB  1 
ATOM   5305 N N   . ILE B 2 68  ? 252.546 171.189 215.118 1.00 82.74  ? 68   ILE C N   1 
ATOM   5306 C CA  . ILE B 2 68  ? 253.817 171.096 215.817 1.00 82.74  ? 68   ILE C CA  1 
ATOM   5307 C C   . ILE B 2 68  ? 254.887 170.639 214.830 1.00 82.74  ? 68   ILE C C   1 
ATOM   5308 O O   . ILE B 2 68  ? 254.610 170.361 213.664 1.00 82.74  ? 68   ILE C O   1 
ATOM   5309 C CB  . ILE B 2 68  ? 253.756 170.147 217.035 1.00 82.74  ? 68   ILE C CB  1 
ATOM   5310 C CG1 . ILE B 2 68  ? 253.550 168.693 216.590 1.00 82.74  ? 68   ILE C CG1 1 
ATOM   5311 C CG2 . ILE B 2 68  ? 252.673 170.586 218.014 1.00 82.74  ? 68   ILE C CG2 1 
ATOM   5312 C CD1 . ILE B 2 68  ? 252.102 168.294 216.374 1.00 82.74  ? 68   ILE C CD1 1 
ATOM   5313 N N   . HIS B 2 69  ? 256.125 170.565 215.321 1.00 93.20  ? 69   HIS C N   1 
ATOM   5314 C CA  . HIS B 2 69  ? 257.253 170.111 214.510 1.00 93.20  ? 69   HIS C CA  1 
ATOM   5315 C C   . HIS B 2 69  ? 258.241 169.428 215.451 1.00 93.20  ? 69   HIS C C   1 
ATOM   5316 O O   . HIS B 2 69  ? 258.988 170.102 216.167 1.00 93.20  ? 69   HIS C O   1 
ATOM   5317 C CB  . HIS B 2 69  ? 257.899 171.270 213.764 1.00 93.20  ? 69   HIS C CB  1 
ATOM   5318 C CG  . HIS B 2 69  ? 259.141 170.892 213.019 1.00 93.20  ? 69   HIS C CG  1 
ATOM   5319 N ND1 . HIS B 2 69  ? 260.400 170.993 213.570 1.00 93.20  ? 69   HIS C ND1 1 
ATOM   5320 C CD2 . HIS B 2 69  ? 259.317 170.413 211.765 1.00 93.20  ? 69   HIS C CD2 1 
ATOM   5321 C CE1 . HIS B 2 69  ? 261.298 170.592 212.689 1.00 93.20  ? 69   HIS C CE1 1 
ATOM   5322 N NE2 . HIS B 2 69  ? 260.667 170.235 211.585 1.00 93.20  ? 69   HIS C NE2 1 
ATOM   5323 N N   . VAL B 2 70  ? 258.238 168.096 215.443 1.00 98.35  ? 70   VAL C N   1 
ATOM   5324 C CA  . VAL B 2 70  ? 259.100 167.315 216.323 1.00 98.35  ? 70   VAL C CA  1 
ATOM   5325 C C   . VAL B 2 70  ? 260.537 167.382 215.826 1.00 98.35  ? 70   VAL C C   1 
ATOM   5326 O O   . VAL B 2 70  ? 260.797 167.800 214.692 1.00 98.35  ? 70   VAL C O   1 
ATOM   5327 C CB  . VAL B 2 70  ? 258.621 165.856 216.417 1.00 98.35  ? 70   VAL C CB  1 
ATOM   5328 C CG1 . VAL B 2 70  ? 257.186 165.801 216.919 1.00 98.35  ? 70   VAL C CG1 1 
ATOM   5329 C CG2 . VAL B 2 70  ? 258.749 165.174 215.065 1.00 98.35  ? 70   VAL C CG2 1 
ATOM   5330 N N   . SER B 2 71  ? 261.477 166.968 216.671 1.00 105.17 ? 71   SER C N   1 
ATOM   5331 C CA  . SER B 2 71  ? 262.889 166.941 216.317 1.00 105.17 ? 71   SER C CA  1 
ATOM   5332 C C   . SER B 2 71  ? 263.294 165.664 215.593 1.00 105.17 ? 71   SER C C   1 
ATOM   5333 O O   . SER B 2 71  ? 264.484 165.475 215.319 1.00 105.17 ? 71   SER C O   1 
ATOM   5334 C CB  . SER B 2 71  ? 263.751 167.114 217.573 1.00 105.17 ? 71   SER C CB  1 
ATOM   5335 O OG  . SER B 2 71  ? 265.130 167.089 217.252 1.00 105.17 ? 71   SER C OG  1 
ATOM   5336 N N   . GLY B 2 72  ? 262.343 164.788 215.279 1.00 105.41 ? 72   GLY C N   1 
ATOM   5337 C CA  . GLY B 2 72  ? 262.650 163.552 214.587 1.00 105.41 ? 72   GLY C CA  1 
ATOM   5338 C C   . GLY B 2 72  ? 261.802 162.385 215.049 1.00 105.41 ? 72   GLY C C   1 
ATOM   5339 O O   . GLY B 2 72  ? 260.668 162.572 215.500 1.00 105.41 ? 72   GLY C O   1 
ATOM   5340 N N   . THR B 2 73  ? 262.341 161.175 214.942 1.00 109.15 ? 73   THR C N   1 
ATOM   5341 C CA  . THR B 2 73  ? 261.617 159.977 215.349 1.00 109.15 ? 73   THR C CA  1 
ATOM   5342 C C   . THR B 2 73  ? 261.602 159.834 216.867 1.00 109.15 ? 73   THR C C   1 
ATOM   5343 O O   . THR B 2 73  ? 262.310 160.551 217.575 1.00 109.15 ? 73   THR C O   1 
ATOM   5344 C CB  . THR B 2 73  ? 262.230 158.709 214.728 1.00 109.15 ? 73   THR C CB  1 
ATOM   5345 O OG1 . THR B 2 73  ? 262.180 158.801 213.299 1.00 109.15 ? 73   THR C OG1 1 
ATOM   5346 C CG2 . THR B 2 73  ? 261.466 157.473 215.179 1.00 109.15 ? 73   THR C CG2 1 
ATOM   5347 N N   . THR B 2 76  ? 256.021 163.363 214.904 1.00 92.83  ? 76   THR C N   1 
ATOM   5348 C CA  . THR B 2 76  ? 255.082 163.517 213.800 1.00 92.83  ? 76   THR C CA  1 
ATOM   5349 C C   . THR B 2 76  ? 254.885 164.986 213.441 1.00 92.83  ? 76   THR C C   1 
ATOM   5350 O O   . THR B 2 76  ? 254.379 165.769 214.245 1.00 92.83  ? 76   THR C O   1 
ATOM   5351 C CB  . THR B 2 76  ? 253.716 162.891 214.134 1.00 92.83  ? 76   THR C CB  1 
ATOM   5352 O OG1 . THR B 2 76  ? 253.877 161.489 214.384 1.00 92.83  ? 76   THR C OG1 1 
ATOM   5353 C CG2 . THR B 2 76  ? 252.744 163.088 212.983 1.00 92.83  ? 76   THR C CG2 1 
ATOM   5354 N N   . LYS B 2 77  ? 255.288 165.354 212.227 1.00 85.78  ? 77   LYS C N   1 
ATOM   5355 C CA  . LYS B 2 77  ? 255.120 166.718 211.735 1.00 85.78  ? 77   LYS C CA  1 
ATOM   5356 C C   . LYS B 2 77  ? 253.675 166.903 211.288 1.00 85.78  ? 77   LYS C C   1 
ATOM   5357 O O   . LYS B 2 77  ? 253.246 166.316 210.290 1.00 85.78  ? 77   LYS C O   1 
ATOM   5358 C CB  . LYS B 2 77  ? 256.090 166.996 210.591 1.00 85.78  ? 77   LYS C CB  1 
ATOM   5359 C CG  . LYS B 2 77  ? 255.982 168.396 210.011 1.00 85.78  ? 77   LYS C CG  1 
ATOM   5360 C CD  . LYS B 2 77  ? 256.909 168.573 208.820 1.00 85.78  ? 77   LYS C CD  1 
ATOM   5361 C CE  . LYS B 2 77  ? 258.356 168.313 209.201 1.00 85.78  ? 77   LYS C CE  1 
ATOM   5362 N NZ  . LYS B 2 77  ? 259.278 168.511 208.049 1.00 85.78  ? 77   LYS C NZ  1 
ATOM   5363 N N   . ARG B 2 78  ? 252.922 167.718 212.022 1.00 83.73  ? 78   ARG C N   1 
ATOM   5364 C CA  . ARG B 2 78  ? 251.509 167.940 211.753 1.00 83.73  ? 78   ARG C CA  1 
ATOM   5365 C C   . ARG B 2 78  ? 251.277 169.390 211.354 1.00 83.73  ? 78   ARG C C   1 
ATOM   5366 O O   . ARG B 2 78  ? 251.741 170.310 212.036 1.00 83.73  ? 78   ARG C O   1 
ATOM   5367 C CB  . ARG B 2 78  ? 250.656 167.587 212.973 1.00 83.73  ? 78   ARG C CB  1 
ATOM   5368 C CG  . ARG B 2 78  ? 250.769 166.138 213.408 1.00 83.73  ? 78   ARG C CG  1 
ATOM   5369 C CD  . ARG B 2 78  ? 249.815 165.827 214.547 1.00 83.73  ? 78   ARG C CD  1 
ATOM   5370 N NE  . ARG B 2 78  ? 248.421 166.019 214.159 1.00 83.73  ? 78   ARG C NE  1 
ATOM   5371 C CZ  . ARG B 2 78  ? 247.384 165.769 214.951 1.00 83.73  ? 78   ARG C CZ  1 
ATOM   5372 N NH1 . ARG B 2 78  ? 246.149 165.973 214.515 1.00 83.73  ? 78   ARG C NH1 1 
ATOM   5373 N NH2 . ARG B 2 78  ? 247.582 165.311 216.180 1.00 83.73  ? 78   ARG C NH2 1 
ATOM   5374 N N   . PHE B 2 79  ? 250.560 169.585 210.251 1.00 78.14  ? 79   PHE C N   1 
ATOM   5375 C CA  . PHE B 2 79  ? 250.148 170.898 209.764 1.00 78.14  ? 79   PHE C CA  1 
ATOM   5376 C C   . PHE B 2 79  ? 248.679 170.856 209.360 1.00 78.14  ? 79   PHE C C   1 
ATOM   5377 O O   . PHE B 2 79  ? 248.284 171.288 208.276 1.00 78.14  ? 79   PHE C O   1 
ATOM   5378 C CB  . PHE B 2 79  ? 251.037 171.348 208.607 1.00 78.14  ? 79   PHE C CB  1 
ATOM   5379 C CG  . PHE B 2 79  ? 250.864 172.793 208.234 1.00 78.14  ? 79   PHE C CG  1 
ATOM   5380 C CD1 . PHE B 2 79  ? 251.137 173.795 209.150 1.00 78.14  ? 79   PHE C CD1 1 
ATOM   5381 C CD2 . PHE B 2 79  ? 250.444 173.150 206.965 1.00 78.14  ? 79   PHE C CD2 1 
ATOM   5382 C CE1 . PHE B 2 79  ? 250.981 175.125 208.810 1.00 78.14  ? 79   PHE C CE1 1 
ATOM   5383 C CE2 . PHE B 2 79  ? 250.287 174.478 206.618 1.00 78.14  ? 79   PHE C CE2 1 
ATOM   5384 C CZ  . PHE B 2 79  ? 250.558 175.466 207.541 1.00 78.14  ? 79   PHE C CZ  1 
ATOM   5385 N N   . ASP B 2 80  ? 247.852 170.308 210.247 1.00 76.39  ? 80   ASP C N   1 
ATOM   5386 C CA  . ASP B 2 80  ? 246.449 170.055 209.939 1.00 76.39  ? 80   ASP C CA  1 
ATOM   5387 C C   . ASP B 2 80  ? 245.696 171.364 209.730 1.00 76.39  ? 80   ASP C C   1 
ATOM   5388 O O   . ASP B 2 80  ? 245.585 172.181 210.650 1.00 76.39  ? 80   ASP C O   1 
ATOM   5389 C CB  . ASP B 2 80  ? 245.805 169.245 211.061 1.00 76.39  ? 80   ASP C CB  1 
ATOM   5390 C CG  . ASP B 2 80  ? 246.494 167.915 211.289 1.00 76.39  ? 80   ASP C CG  1 
ATOM   5391 O OD1 . ASP B 2 80  ? 247.472 167.619 210.571 1.00 76.39  ? 80   ASP C OD1 1 
ATOM   5392 O OD2 . ASP B 2 80  ? 246.057 167.164 212.186 1.00 76.39  ? 80   ASP C OD2 1 
ATOM   5393 N N   . ASN B 2 81  ? 245.179 171.560 208.516 1.00 71.66  ? 81   ASN C N   1 
ATOM   5394 C CA  . ASN B 2 81  ? 244.278 172.674 208.216 1.00 71.66  ? 81   ASN C CA  1 
ATOM   5395 C C   . ASN B 2 81  ? 243.253 172.212 207.188 1.00 71.66  ? 81   ASN C C   1 
ATOM   5396 O O   . ASN B 2 81  ? 243.224 172.690 206.048 1.00 71.66  ? 81   ASN C O   1 
ATOM   5397 C CB  . ASN B 2 81  ? 245.061 173.890 207.718 1.00 71.66  ? 81   ASN C CB  1 
ATOM   5398 C CG  . ASN B 2 81  ? 246.048 173.544 206.619 1.00 71.66  ? 81   ASN C CG  1 
ATOM   5399 O OD1 . ASN B 2 81  ? 245.750 173.683 205.433 1.00 71.66  ? 81   ASN C OD1 1 
ATOM   5400 N ND2 . ASN B 2 81  ? 247.234 173.095 207.010 1.00 71.66  ? 81   ASN C ND2 1 
ATOM   5401 N N   . PRO B 2 82  ? 242.381 171.282 207.566 1.00 67.84  ? 82   PRO C N   1 
ATOM   5402 C CA  . PRO B 2 82  ? 241.431 170.720 206.604 1.00 67.84  ? 82   PRO C CA  1 
ATOM   5403 C C   . PRO B 2 82  ? 240.224 171.630 206.413 1.00 67.84  ? 82   PRO C C   1 
ATOM   5404 O O   . PRO B 2 82  ? 240.009 172.596 207.144 1.00 67.84  ? 82   PRO C O   1 
ATOM   5405 C CB  . PRO B 2 82  ? 241.028 169.396 207.255 1.00 67.84  ? 82   PRO C CB  1 
ATOM   5406 C CG  . PRO B 2 82  ? 241.082 169.696 208.712 1.00 67.84  ? 82   PRO C CG  1 
ATOM   5407 C CD  . PRO B 2 82  ? 242.201 170.698 208.908 1.00 67.84  ? 82   PRO C CD  1 
ATOM   5408 N N   . VAL B 2 83  ? 239.431 171.294 205.400 1.00 64.73  ? 83   VAL C N   1 
ATOM   5409 C CA  . VAL B 2 83  ? 238.207 172.030 205.099 1.00 64.73  ? 83   VAL C CA  1 
ATOM   5410 C C   . VAL B 2 83  ? 237.101 171.488 206.000 1.00 64.73  ? 83   VAL C C   1 
ATOM   5411 O O   . VAL B 2 83  ? 236.664 170.346 205.845 1.00 64.73  ? 83   VAL C O   1 
ATOM   5412 C CB  . VAL B 2 83  ? 237.830 171.911 203.619 1.00 64.73  ? 83   VAL C CB  1 
ATOM   5413 C CG1 . VAL B 2 83  ? 236.666 172.828 203.296 1.00 64.73  ? 83   VAL C CG1 1 
ATOM   5414 C CG2 . VAL B 2 83  ? 239.028 172.233 202.740 1.00 64.73  ? 83   VAL C CG2 1 
ATOM   5415 N N   . LEU B 2 84  ? 236.647 172.312 206.951 1.00 64.17  ? 84   LEU C N   1 
ATOM   5416 C CA  . LEU B 2 84  ? 235.651 171.906 207.927 1.00 64.17  ? 84   LEU C CA  1 
ATOM   5417 C C   . LEU B 2 84  ? 234.277 172.458 207.564 1.00 64.17  ? 84   LEU C C   1 
ATOM   5418 O O   . LEU B 2 84  ? 234.169 173.554 207.007 1.00 64.17  ? 84   LEU C O   1 
ATOM   5419 C CB  . LEU B 2 84  ? 236.038 172.395 209.325 1.00 64.17  ? 84   LEU C CB  1 
ATOM   5420 C CG  . LEU B 2 84  ? 237.401 171.938 209.841 1.00 64.17  ? 84   LEU C CG  1 
ATOM   5421 C CD1 . LEU B 2 84  ? 237.686 172.558 211.197 1.00 64.17  ? 84   LEU C CD1 1 
ATOM   5422 C CD2 . LEU B 2 84  ? 237.463 170.422 209.914 1.00 64.17  ? 84   LEU C CD2 1 
ATOM   5423 N N   . PRO B 2 85  ? 233.211 171.722 207.869 1.00 61.71  ? 85   PRO C N   1 
ATOM   5424 C CA  . PRO B 2 85  ? 231.866 172.204 207.544 1.00 61.71  ? 85   PRO C CA  1 
ATOM   5425 C C   . PRO B 2 85  ? 231.449 173.364 208.435 1.00 61.71  ? 85   PRO C C   1 
ATOM   5426 O O   . PRO B 2 85  ? 232.036 173.629 209.486 1.00 61.71  ? 85   PRO C O   1 
ATOM   5427 C CB  . PRO B 2 85  ? 230.982 170.976 207.784 1.00 61.71  ? 85   PRO C CB  1 
ATOM   5428 C CG  . PRO B 2 85  ? 231.729 170.178 208.797 1.00 61.71  ? 85   PRO C CG  1 
ATOM   5429 C CD  . PRO B 2 85  ? 233.186 170.385 208.487 1.00 61.71  ? 85   PRO C CD  1 
ATOM   5430 N N   . PHE B 2 86  ? 230.408 174.066 207.987 1.00 63.91  ? 86   PHE C N   1 
ATOM   5431 C CA  . PHE B 2 86  ? 229.840 175.216 208.692 1.00 63.91  ? 86   PHE C CA  1 
ATOM   5432 C C   . PHE B 2 86  ? 228.326 175.028 208.699 1.00 63.91  ? 86   PHE C C   1 
ATOM   5433 O O   . PHE B 2 86  ? 227.633 175.464 207.776 1.00 63.91  ? 86   PHE C O   1 
ATOM   5434 C CB  . PHE B 2 86  ? 230.256 176.527 208.025 1.00 63.91  ? 86   PHE C CB  1 
ATOM   5435 C CG  . PHE B 2 86  ? 229.854 177.757 208.789 1.00 63.91  ? 86   PHE C CG  1 
ATOM   5436 C CD1 . PHE B 2 86  ? 228.634 178.368 208.554 1.00 63.91  ? 86   PHE C CD1 1 
ATOM   5437 C CD2 . PHE B 2 86  ? 230.702 178.308 209.733 1.00 63.91  ? 86   PHE C CD2 1 
ATOM   5438 C CE1 . PHE B 2 86  ? 228.265 179.502 209.252 1.00 63.91  ? 86   PHE C CE1 1 
ATOM   5439 C CE2 . PHE B 2 86  ? 230.339 179.442 210.435 1.00 63.91  ? 86   PHE C CE2 1 
ATOM   5440 C CZ  . PHE B 2 86  ? 229.119 180.039 210.193 1.00 63.91  ? 86   PHE C CZ  1 
ATOM   5441 N N   . ASN B 2 87  ? 227.813 174.372 209.741 1.00 64.88  ? 87   ASN C N   1 
ATOM   5442 C CA  . ASN B 2 87  ? 226.391 174.051 209.794 1.00 64.88  ? 87   ASN C CA  1 
ATOM   5443 C C   . ASN B 2 87  ? 225.559 175.275 210.163 1.00 64.88  ? 87   ASN C C   1 
ATOM   5444 O O   . ASN B 2 87  ? 224.732 175.740 209.372 1.00 64.88  ? 87   ASN C O   1 
ATOM   5445 C CB  . ASN B 2 87  ? 226.150 172.914 210.791 1.00 64.88  ? 87   ASN C CB  1 
ATOM   5446 C CG  . ASN B 2 87  ? 227.006 171.696 210.504 1.00 64.88  ? 87   ASN C CG  1 
ATOM   5447 O OD1 . ASN B 2 87  ? 227.341 171.416 209.354 1.00 64.88  ? 87   ASN C OD1 1 
ATOM   5448 N ND2 . ASN B 2 87  ? 227.366 170.966 211.553 1.00 64.88  ? 87   ASN C ND2 1 
ATOM   5449 N N   . ASP B 2 88  ? 225.772 175.813 211.364 1.00 65.03  ? 88   ASP C N   1 
ATOM   5450 C CA  . ASP B 2 88  ? 225.064 176.999 211.822 1.00 65.03  ? 88   ASP C CA  1 
ATOM   5451 C C   . ASP B 2 88  ? 225.972 178.041 212.454 1.00 65.03  ? 88   ASP C C   1 
ATOM   5452 O O   . ASP B 2 88  ? 225.516 179.166 212.689 1.00 65.03  ? 88   ASP C O   1 
ATOM   5453 C CB  . ASP B 2 88  ? 223.972 176.619 212.836 1.00 65.03  ? 88   ASP C CB  1 
ATOM   5454 C CG  . ASP B 2 88  ? 222.883 175.758 212.228 1.00 65.03  ? 88   ASP C CG  1 
ATOM   5455 O OD1 . ASP B 2 88  ? 222.497 176.015 211.068 1.00 65.03  ? 88   ASP C OD1 1 
ATOM   5456 O OD2 . ASP B 2 88  ? 222.414 174.824 212.910 1.00 65.03  ? 88   ASP C OD2 1 
ATOM   5457 N N   . GLY B 2 89  ? 227.229 177.711 212.731 1.00 62.69  ? 89   GLY C N   1 
ATOM   5458 C CA  . GLY B 2 89  ? 228.145 178.620 213.386 1.00 62.69  ? 89   GLY C CA  1 
ATOM   5459 C C   . GLY B 2 89  ? 229.263 177.863 214.068 1.00 62.69  ? 89   GLY C C   1 
ATOM   5460 O O   . GLY B 2 89  ? 229.027 176.807 214.662 1.00 62.69  ? 89   GLY C O   1 
ATOM   5461 N N   . VAL B 2 90  ? 230.484 178.382 213.991 1.00 61.40  ? 90   VAL C N   1 
ATOM   5462 C CA  . VAL B 2 90  ? 231.657 177.707 214.529 1.00 61.40  ? 90   VAL C CA  1 
ATOM   5463 C C   . VAL B 2 90  ? 232.268 178.564 215.628 1.00 61.40  ? 90   VAL C C   1 
ATOM   5464 O O   . VAL B 2 90  ? 232.269 179.797 215.544 1.00 61.40  ? 90   VAL C O   1 
ATOM   5465 C CB  . VAL B 2 90  ? 232.694 177.402 213.428 1.00 61.40  ? 90   VAL C CB  1 
ATOM   5466 C CG1 . VAL B 2 90  ? 232.144 176.365 212.464 1.00 61.40  ? 90   VAL C CG1 1 
ATOM   5467 C CG2 . VAL B 2 90  ? 233.074 178.672 212.684 1.00 61.40  ? 90   VAL C CG2 1 
ATOM   5468 N N   . TYR B 2 91  ? 232.775 177.902 216.664 1.00 61.11  ? 91   TYR C N   1 
ATOM   5469 C CA  . TYR B 2 91  ? 233.506 178.552 217.746 1.00 61.11  ? 91   TYR C CA  1 
ATOM   5470 C C   . TYR B 2 91  ? 234.990 178.274 217.538 1.00 61.11  ? 91   TYR C C   1 
ATOM   5471 O O   . TYR B 2 91  ? 235.446 177.140 217.717 1.00 61.11  ? 91   TYR C O   1 
ATOM   5472 C CB  . TYR B 2 91  ? 233.030 178.048 219.107 1.00 61.11  ? 91   TYR C CB  1 
ATOM   5473 C CG  . TYR B 2 91  ? 233.954 178.398 220.252 1.00 61.11  ? 91   TYR C CG  1 
ATOM   5474 C CD1 . TYR B 2 91  ? 233.952 179.670 220.808 1.00 61.11  ? 91   TYR C CD1 1 
ATOM   5475 C CD2 . TYR B 2 91  ? 234.823 177.453 220.783 1.00 61.11  ? 91   TYR C CD2 1 
ATOM   5476 C CE1 . TYR B 2 91  ? 234.794 179.992 221.856 1.00 61.11  ? 91   TYR C CE1 1 
ATOM   5477 C CE2 . TYR B 2 91  ? 235.668 177.766 221.829 1.00 61.11  ? 91   TYR C CE2 1 
ATOM   5478 C CZ  . TYR B 2 91  ? 235.649 179.037 222.362 1.00 61.11  ? 91   TYR C CZ  1 
ATOM   5479 O OH  . TYR B 2 91  ? 236.488 179.352 223.406 1.00 61.11  ? 91   TYR C OH  1 
ATOM   5480 N N   . PHE B 2 92  ? 235.738 179.304 217.157 1.00 62.27  ? 92   PHE C N   1 
ATOM   5481 C CA  . PHE B 2 92  ? 237.153 179.170 216.841 1.00 62.27  ? 92   PHE C CA  1 
ATOM   5482 C C   . PHE B 2 92  ? 237.981 179.744 217.984 1.00 62.27  ? 92   PHE C C   1 
ATOM   5483 O O   . PHE B 2 92  ? 237.932 180.950 218.246 1.00 62.27  ? 92   PHE C O   1 
ATOM   5484 C CB  . PHE B 2 92  ? 237.484 179.877 215.527 1.00 62.27  ? 92   PHE C CB  1 
ATOM   5485 C CG  . PHE B 2 92  ? 238.777 179.432 214.908 1.00 62.27  ? 92   PHE C CG  1 
ATOM   5486 C CD1 . PHE B 2 92  ? 239.976 180.021 215.273 1.00 62.27  ? 92   PHE C CD1 1 
ATOM   5487 C CD2 . PHE B 2 92  ? 238.793 178.424 213.960 1.00 62.27  ? 92   PHE C CD2 1 
ATOM   5488 C CE1 . PHE B 2 92  ? 241.165 179.612 214.703 1.00 62.27  ? 92   PHE C CE1 1 
ATOM   5489 C CE2 . PHE B 2 92  ? 239.979 178.011 213.387 1.00 62.27  ? 92   PHE C CE2 1 
ATOM   5490 C CZ  . PHE B 2 92  ? 241.167 178.606 213.760 1.00 62.27  ? 92   PHE C CZ  1 
ATOM   5491 N N   . ALA B 2 93  ? 238.737 178.882 218.656 1.00 65.16  ? 93   ALA C N   1 
ATOM   5492 C CA  . ALA B 2 93  ? 239.627 179.278 219.738 1.00 65.16  ? 93   ALA C CA  1 
ATOM   5493 C C   . ALA B 2 93  ? 241.067 179.020 219.317 1.00 65.16  ? 93   ALA C C   1 
ATOM   5494 O O   . ALA B 2 93  ? 241.388 177.931 218.832 1.00 65.16  ? 93   ALA C O   1 
ATOM   5495 C CB  . ALA B 2 93  ? 239.303 178.518 221.026 1.00 65.16  ? 93   ALA C CB  1 
ATOM   5496 N N   . SER B 2 94  ? 241.927 180.018 219.504 1.00 67.56  ? 94   SER C N   1 
ATOM   5497 C CA  . SER B 2 94  ? 243.316 179.955 219.067 1.00 67.56  ? 94   SER C CA  1 
ATOM   5498 C C   . SER B 2 94  ? 244.230 180.033 220.281 1.00 67.56  ? 94   SER C C   1 
ATOM   5499 O O   . SER B 2 94  ? 244.163 180.997 221.050 1.00 67.56  ? 94   SER C O   1 
ATOM   5500 C CB  . SER B 2 94  ? 243.635 181.086 218.088 1.00 67.56  ? 94   SER C CB  1 
ATOM   5501 O OG  . SER B 2 94  ? 242.759 181.060 216.976 1.00 67.56  ? 94   SER C OG  1 
ATOM   5502 N N   . THR B 2 95  ? 245.080 179.025 220.447 1.00 70.43  ? 95   THR C N   1 
ATOM   5503 C CA  . THR B 2 95  ? 246.108 179.006 221.485 1.00 70.43  ? 95   THR C CA  1 
ATOM   5504 C C   . THR B 2 95  ? 247.454 179.135 220.780 1.00 70.43  ? 95   THR C C   1 
ATOM   5505 O O   . THR B 2 95  ? 247.996 178.150 220.272 1.00 70.43  ? 95   THR C O   1 
ATOM   5506 C CB  . THR B 2 95  ? 246.031 177.731 222.320 1.00 70.43  ? 95   THR C CB  1 
ATOM   5507 O OG1 . THR B 2 95  ? 246.222 176.591 221.473 1.00 70.43  ? 95   THR C OG1 1 
ATOM   5508 C CG2 . THR B 2 95  ? 244.677 177.625 223.004 1.00 70.43  ? 95   THR C CG2 1 
ATOM   5509 N N   . GLU B 2 96  ? 247.990 180.352 220.751 1.00 74.14  ? 96   GLU C N   1 
ATOM   5510 C CA  . GLU B 2 96  ? 249.173 180.664 219.966 1.00 74.14  ? 96   GLU C CA  1 
ATOM   5511 C C   . GLU B 2 96  ? 250.302 181.175 220.849 1.00 74.14  ? 96   GLU C C   1 
ATOM   5512 O O   . GLU B 2 96  ? 250.099 181.574 221.999 1.00 74.14  ? 96   GLU C O   1 
ATOM   5513 C CB  . GLU B 2 96  ? 248.864 181.713 218.891 1.00 74.14  ? 96   GLU C CB  1 
ATOM   5514 C CG  . GLU B 2 96  ? 248.061 181.197 217.717 1.00 74.14  ? 96   GLU C CG  1 
ATOM   5515 C CD  . GLU B 2 96  ? 247.821 182.270 216.676 1.00 74.14  ? 96   GLU C CD  1 
ATOM   5516 O OE1 . GLU B 2 96  ? 247.371 183.373 217.050 1.00 74.14  ? 96   GLU C OE1 1 
ATOM   5517 O OE2 . GLU B 2 96  ? 248.097 182.016 215.487 1.00 74.14  ? 96   GLU C OE2 1 
ATOM   5518 N N   . LYS B 2 97  ? 251.505 181.155 220.279 1.00 79.61  ? 97   LYS C N   1 
ATOM   5519 C CA  . LYS B 2 97  ? 252.677 181.777 220.880 1.00 79.61  ? 97   LYS C CA  1 
ATOM   5520 C C   . LYS B 2 97  ? 253.457 182.658 219.917 1.00 79.61  ? 97   LYS C C   1 
ATOM   5521 O O   . LYS B 2 97  ? 254.237 183.498 220.380 1.00 79.61  ? 97   LYS C O   1 
ATOM   5522 C CB  . LYS B 2 97  ? 253.626 180.710 221.448 1.00 79.61  ? 97   LYS C CB  1 
ATOM   5523 C CG  . LYS B 2 97  ? 254.164 179.744 220.405 1.00 79.61  ? 97   LYS C CG  1 
ATOM   5524 C CD  . LYS B 2 97  ? 255.232 178.833 220.987 1.00 79.61  ? 97   LYS C CD  1 
ATOM   5525 C CE  . LYS B 2 97  ? 254.694 178.014 222.148 1.00 79.61  ? 97   LYS C CE  1 
ATOM   5526 N NZ  . LYS B 2 97  ? 255.722 177.083 222.690 1.00 79.61  ? 97   LYS C NZ  1 
ATOM   5527 N N   . SER B 2 98  ? 253.277 182.500 218.600 1.00 80.39  ? 98   SER C N   1 
ATOM   5528 C CA  . SER B 2 98  ? 253.992 183.314 217.625 1.00 80.39  ? 98   SER C CA  1 
ATOM   5529 C C   . SER B 2 98  ? 253.096 183.753 216.470 1.00 80.39  ? 98   SER C C   1 
ATOM   5530 O O   . SER B 2 98  ? 253.608 184.048 215.382 1.00 80.39  ? 98   SER C O   1 
ATOM   5531 C CB  . SER B 2 98  ? 255.206 182.559 217.074 1.00 80.39  ? 98   SER C CB  1 
ATOM   5532 O OG  . SER B 2 98  ? 255.894 183.335 216.109 1.00 80.39  ? 98   SER C OG  1 
ATOM   5533 N N   . ASN B 2 99  ? 251.778 183.799 216.677 1.00 76.79  ? 99   ASN C N   1 
ATOM   5534 C CA  . ASN B 2 99  ? 250.816 184.231 215.661 1.00 76.79  ? 99   ASN C CA  1 
ATOM   5535 C C   . ASN B 2 99  ? 250.916 183.368 214.401 1.00 76.79  ? 99   ASN C C   1 
ATOM   5536 O O   . ASN B 2 99  ? 251.252 183.839 213.312 1.00 76.79  ? 99   ASN C O   1 
ATOM   5537 C CB  . ASN B 2 99  ? 250.996 185.717 215.329 1.00 76.79  ? 99   ASN C CB  1 
ATOM   5538 C CG  . ASN B 2 99  ? 250.768 186.613 216.529 1.00 76.79  ? 99   ASN C CG  1 
ATOM   5539 O OD1 . ASN B 2 99  ? 251.666 187.339 216.955 1.00 76.79  ? 99   ASN C OD1 1 
ATOM   5540 N ND2 . ASN B 2 99  ? 249.562 186.567 217.081 1.00 76.79  ? 99   ASN C ND2 1 
ATOM   5541 N N   . ILE B 2 100 ? 250.617 182.080 214.570 1.00 73.95  ? 100  ILE C N   1 
ATOM   5542 C CA  . ILE B 2 100 ? 250.658 181.156 213.442 1.00 73.95  ? 100  ILE C CA  1 
ATOM   5543 C C   . ILE B 2 100 ? 249.401 181.284 212.590 1.00 73.95  ? 100  ILE C C   1 
ATOM   5544 O O   . ILE B 2 100 ? 249.473 181.297 211.356 1.00 73.95  ? 100  ILE C O   1 
ATOM   5545 C CB  . ILE B 2 100 ? 250.860 179.715 213.943 1.00 73.95  ? 100  ILE C CB  1 
ATOM   5546 C CG1 . ILE B 2 100 ? 252.163 179.605 214.736 1.00 73.95  ? 100  ILE C CG1 1 
ATOM   5547 C CG2 . ILE B 2 100 ? 250.865 178.739 212.778 1.00 73.95  ? 100  ILE C CG2 1 
ATOM   5548 C CD1 . ILE B 2 100 ? 253.394 179.956 213.933 1.00 73.95  ? 100  ILE C CD1 1 
ATOM   5549 N N   . ILE B 2 101 ? 248.236 181.383 213.226 1.00 69.06  ? 101  ILE C N   1 
ATOM   5550 C CA  . ILE B 2 101 ? 246.980 181.493 212.492 1.00 69.06  ? 101  ILE C CA  1 
ATOM   5551 C C   . ILE B 2 101 ? 246.861 182.900 211.923 1.00 69.06  ? 101  ILE C C   1 
ATOM   5552 O O   . ILE B 2 101 ? 246.906 183.891 212.661 1.00 69.06  ? 101  ILE C O   1 
ATOM   5553 C CB  . ILE B 2 101 ? 245.787 181.157 213.395 1.00 69.06  ? 101  ILE C CB  1 
ATOM   5554 C CG1 . ILE B 2 101 ? 246.014 179.819 214.098 1.00 69.06  ? 101  ILE C CG1 1 
ATOM   5555 C CG2 . ILE B 2 101 ? 244.500 181.125 212.585 1.00 69.06  ? 101  ILE C CG2 1 
ATOM   5556 C CD1 . ILE B 2 101 ? 244.906 179.435 215.044 1.00 69.06  ? 101  ILE C CD1 1 
ATOM   5557 N N   . ARG B 2 102 ? 246.706 182.993 210.604 1.00 71.14  ? 102  ARG C N   1 
ATOM   5558 C CA  . ARG B 2 102 ? 246.577 184.279 209.932 1.00 71.14  ? 102  ARG C CA  1 
ATOM   5559 C C   . ARG B 2 102 ? 245.136 184.661 209.633 1.00 71.14  ? 102  ARG C C   1 
ATOM   5560 O O   . ARG B 2 102 ? 244.816 185.854 209.619 1.00 71.14  ? 102  ARG C O   1 
ATOM   5561 C CB  . ARG B 2 102 ? 247.376 184.279 208.624 1.00 71.14  ? 102  ARG C CB  1 
ATOM   5562 C CG  . ARG B 2 102 ? 248.883 184.196 208.809 1.00 71.14  ? 102  ARG C CG  1 
ATOM   5563 C CD  . ARG B 2 102 ? 249.391 185.317 209.700 1.00 71.14  ? 102  ARG C CD  1 
ATOM   5564 N NE  . ARG B 2 102 ? 250.806 185.597 209.477 1.00 71.14  ? 102  ARG C NE  1 
ATOM   5565 C CZ  . ARG B 2 102 ? 251.798 185.009 210.137 1.00 71.14  ? 102  ARG C CZ  1 
ATOM   5566 N NH1 . ARG B 2 102 ? 253.056 185.327 209.868 1.00 71.14  ? 102  ARG C NH1 1 
ATOM   5567 N NH2 . ARG B 2 102 ? 251.532 184.102 211.066 1.00 71.14  ? 102  ARG C NH2 1 
ATOM   5568 N N   . GLY B 2 103 ? 244.263 183.688 209.394 1.00 66.46  ? 103  GLY C N   1 
ATOM   5569 C CA  . GLY B 2 103 ? 242.877 183.998 209.101 1.00 66.46  ? 103  GLY C CA  1 
ATOM   5570 C C   . GLY B 2 103 ? 242.114 182.749 208.706 1.00 66.46  ? 103  GLY C C   1 
ATOM   5571 O O   . GLY B 2 103 ? 242.523 181.630 209.022 1.00 66.46  ? 103  GLY C O   1 
ATOM   5572 N N   . TRP B 2 104 ? 240.998 182.963 208.011 1.00 63.11  ? 104  TRP C N   1 
ATOM   5573 C CA  . TRP B 2 104 ? 240.118 181.879 207.604 1.00 63.11  ? 104  TRP C CA  1 
ATOM   5574 C C   . TRP B 2 104 ? 239.632 182.125 206.183 1.00 63.11  ? 104  TRP C C   1 
ATOM   5575 O O   . TRP B 2 104 ? 239.720 183.236 205.656 1.00 63.11  ? 104  TRP C O   1 
ATOM   5576 C CB  . TRP B 2 104 ? 238.918 181.740 208.549 1.00 63.11  ? 104  TRP C CB  1 
ATOM   5577 C CG  . TRP B 2 104 ? 239.292 181.716 209.996 1.00 63.11  ? 104  TRP C CG  1 
ATOM   5578 C CD1 . TRP B 2 104 ? 239.527 180.614 210.764 1.00 63.11  ? 104  TRP C CD1 1 
ATOM   5579 C CD2 . TRP B 2 104 ? 239.476 182.849 210.853 1.00 63.11  ? 104  TRP C CD2 1 
ATOM   5580 N NE1 . TRP B 2 104 ? 239.845 180.990 212.045 1.00 63.11  ? 104  TRP C NE1 1 
ATOM   5581 C CE2 . TRP B 2 104 ? 239.821 182.357 212.126 1.00 63.11  ? 104  TRP C CE2 1 
ATOM   5582 C CE3 . TRP B 2 104 ? 239.382 184.231 210.666 1.00 63.11  ? 104  TRP C CE3 1 
ATOM   5583 C CZ2 . TRP B 2 104 ? 240.073 183.198 213.208 1.00 63.11  ? 104  TRP C CZ2 1 
ATOM   5584 C CZ3 . TRP B 2 104 ? 239.632 185.064 211.740 1.00 63.11  ? 104  TRP C CZ3 1 
ATOM   5585 C CH2 . TRP B 2 104 ? 239.974 184.545 212.995 1.00 63.11  ? 104  TRP C CH2 1 
ATOM   5586 N N   . ILE B 2 105 ? 239.112 181.065 205.568 1.00 67.40  ? 105  ILE C N   1 
ATOM   5587 C CA  . ILE B 2 105 ? 238.566 181.112 204.215 1.00 67.40  ? 105  ILE C CA  1 
ATOM   5588 C C   . ILE B 2 105 ? 237.162 180.524 204.284 1.00 67.40  ? 105  ILE C C   1 
ATOM   5589 O O   . ILE B 2 105 ? 236.997 179.300 204.322 1.00 67.40  ? 105  ILE C O   1 
ATOM   5590 C CB  . ILE B 2 105 ? 239.432 180.352 203.205 1.00 67.40  ? 105  ILE C CB  1 
ATOM   5591 C CG1 . ILE B 2 105 ? 240.814 180.996 203.088 1.00 67.40  ? 105  ILE C CG1 1 
ATOM   5592 C CG2 . ILE B 2 105 ? 238.751 180.304 201.847 1.00 67.40  ? 105  ILE C CG2 1 
ATOM   5593 C CD1 . ILE B 2 105 ? 241.711 180.318 202.079 1.00 67.40  ? 105  ILE C CD1 1 
ATOM   5594 N N   . PHE B 2 106 ? 236.151 181.385 204.302 1.00 65.80  ? 106  PHE C N   1 
ATOM   5595 C CA  . PHE B 2 106 ? 234.766 180.942 204.341 1.00 65.80  ? 106  PHE C CA  1 
ATOM   5596 C C   . PHE B 2 106 ? 234.194 180.857 202.932 1.00 65.80  ? 106  PHE C C   1 
ATOM   5597 O O   . PHE B 2 106 ? 234.645 181.546 202.014 1.00 65.80  ? 106  PHE C O   1 
ATOM   5598 C CB  . PHE B 2 106 ? 233.916 181.888 205.191 1.00 65.80  ? 106  PHE C CB  1 
ATOM   5599 C CG  . PHE B 2 106 ? 234.346 181.966 206.627 1.00 65.80  ? 106  PHE C CG  1 
ATOM   5600 C CD1 . PHE B 2 106 ? 235.230 182.945 207.047 1.00 65.80  ? 106  PHE C CD1 1 
ATOM   5601 C CD2 . PHE B 2 106 ? 233.865 181.061 207.557 1.00 65.80  ? 106  PHE C CD2 1 
ATOM   5602 C CE1 . PHE B 2 106 ? 235.625 183.020 208.368 1.00 65.80  ? 106  PHE C CE1 1 
ATOM   5603 C CE2 . PHE B 2 106 ? 234.258 181.130 208.879 1.00 65.80  ? 106  PHE C CE2 1 
ATOM   5604 C CZ  . PHE B 2 106 ? 235.139 182.111 209.285 1.00 65.80  ? 106  PHE C CZ  1 
ATOM   5605 N N   . GLY B 2 107 ? 233.188 180.003 202.771 1.00 68.98  ? 107  GLY C N   1 
ATOM   5606 C CA  . GLY B 2 107 ? 232.559 179.837 201.474 1.00 68.98  ? 107  GLY C CA  1 
ATOM   5607 C C   . GLY B 2 107 ? 231.702 178.588 201.448 1.00 68.98  ? 107  GLY C C   1 
ATOM   5608 O O   . GLY B 2 107 ? 231.379 178.018 202.491 1.00 68.98  ? 107  GLY C O   1 
ATOM   5609 N N   . THR B 2 108 ? 231.340 178.175 200.233 1.00 72.34  ? 108  THR C N   1 
ATOM   5610 C CA  . THR B 2 108 ? 230.522 176.988 200.022 1.00 72.34  ? 108  THR C CA  1 
ATOM   5611 C C   . THR B 2 108 ? 231.318 175.858 199.382 1.00 72.34  ? 108  THR C C   1 
ATOM   5612 O O   . THR B 2 108 ? 231.366 174.749 199.921 1.00 72.34  ? 108  THR C O   1 
ATOM   5613 C CB  . THR B 2 108 ? 229.300 177.333 199.160 1.00 72.34  ? 108  THR C CB  1 
ATOM   5614 O OG1 . THR B 2 108 ? 228.528 178.352 199.807 1.00 72.34  ? 108  THR C OG1 1 
ATOM   5615 C CG2 . THR B 2 108 ? 228.431 176.103 198.951 1.00 72.34  ? 108  THR C CG2 1 
ATOM   5616 N N   . THR B 2 109 ? 231.950 176.111 198.235 1.00 77.81  ? 109  THR C N   1 
ATOM   5617 C CA  . THR B 2 109 ? 232.780 175.118 197.572 1.00 77.81  ? 109  THR C CA  1 
ATOM   5618 C C   . THR B 2 109 ? 234.221 175.562 197.375 1.00 77.81  ? 109  THR C C   1 
ATOM   5619 O O   . THR B 2 109 ? 235.036 174.754 196.914 1.00 77.81  ? 109  THR C O   1 
ATOM   5620 C CB  . THR B 2 109 ? 232.189 174.743 196.202 1.00 77.81  ? 109  THR C CB  1 
ATOM   5621 O OG1 . THR B 2 109 ? 232.185 175.893 195.348 1.00 77.81  ? 109  THR C OG1 1 
ATOM   5622 C CG2 . THR B 2 109 ? 230.767 174.225 196.357 1.00 77.81  ? 109  THR C CG2 1 
ATOM   5623 N N   . LEU B 2 110 ? 234.557 176.811 197.709 1.00 77.21  ? 110  LEU C N   1 
ATOM   5624 C CA  . LEU B 2 110 ? 235.916 177.337 197.567 1.00 77.21  ? 110  LEU C CA  1 
ATOM   5625 C C   . LEU B 2 110 ? 236.410 177.217 196.127 1.00 77.21  ? 110  LEU C C   1 
ATOM   5626 O O   . LEU B 2 110 ? 237.554 176.836 195.872 1.00 77.21  ? 110  LEU C O   1 
ATOM   5627 C CB  . LEU B 2 110 ? 236.886 176.652 198.535 1.00 77.21  ? 110  LEU C CB  1 
ATOM   5628 C CG  . LEU B 2 110 ? 236.767 176.973 200.029 1.00 77.21  ? 110  LEU C CG  1 
ATOM   5629 C CD1 . LEU B 2 110 ? 235.608 176.228 200.679 1.00 77.21  ? 110  LEU C CD1 1 
ATOM   5630 C CD2 . LEU B 2 110 ? 238.073 176.664 200.746 1.00 77.21  ? 110  LEU C CD2 1 
ATOM   5631 N N   . ASP B 2 111 ? 235.540 177.546 195.180 1.00 82.20  ? 111  ASP C N   1 
ATOM   5632 C CA  . ASP B 2 111 ? 235.844 177.485 193.757 1.00 82.20  ? 111  ASP C CA  1 
ATOM   5633 C C   . ASP B 2 111 ? 235.575 178.843 193.117 1.00 82.20  ? 111  ASP C C   1 
ATOM   5634 O O   . ASP B 2 111 ? 235.154 179.797 193.776 1.00 82.20  ? 111  ASP C O   1 
ATOM   5635 C CB  . ASP B 2 111 ? 235.026 176.385 193.073 1.00 82.20  ? 111  ASP C CB  1 
ATOM   5636 C CG  . ASP B 2 111 ? 235.293 175.012 193.658 1.00 82.20  ? 111  ASP C CG  1 
ATOM   5637 O OD1 . ASP B 2 111 ? 236.430 174.767 194.111 1.00 82.20  ? 111  ASP C OD1 1 
ATOM   5638 O OD2 . ASP B 2 111 ? 234.364 174.177 193.665 1.00 82.20  ? 111  ASP C OD2 1 
ATOM   5639 N N   . SER B 2 112 ? 235.823 178.923 191.811 1.00 81.27  ? 112  SER C N   1 
ATOM   5640 C CA  . SER B 2 112 ? 235.605 180.152 191.060 1.00 81.27  ? 112  SER C CA  1 
ATOM   5641 C C   . SER B 2 112 ? 234.169 180.311 190.581 1.00 81.27  ? 112  SER C C   1 
ATOM   5642 O O   . SER B 2 112 ? 233.856 181.322 189.942 1.00 81.27  ? 112  SER C O   1 
ATOM   5643 C CB  . SER B 2 112 ? 236.553 180.210 189.859 1.00 81.27  ? 112  SER C CB  1 
ATOM   5644 O OG  . SER B 2 112 ? 237.907 180.189 190.277 1.00 81.27  ? 112  SER C OG  1 
ATOM   5645 N N   . LYS B 2 113 ? 233.292 179.350 190.869 1.00 82.47  ? 113  LYS C N   1 
ATOM   5646 C CA  . LYS B 2 113 ? 231.904 179.432 190.437 1.00 82.47  ? 113  LYS C CA  1 
ATOM   5647 C C   . LYS B 2 113 ? 231.002 180.117 191.453 1.00 82.47  ? 113  LYS C C   1 
ATOM   5648 O O   . LYS B 2 113 ? 229.956 180.653 191.068 1.00 82.47  ? 113  LYS C O   1 
ATOM   5649 C CB  . LYS B 2 113 ? 231.360 178.031 190.135 1.00 82.47  ? 113  LYS C CB  1 
ATOM   5650 C CG  . LYS B 2 113 ? 231.415 177.073 191.312 1.00 82.47  ? 113  LYS C CG  1 
ATOM   5651 C CD  . LYS B 2 113 ? 230.898 175.698 190.923 1.00 82.47  ? 113  LYS C CD  1 
ATOM   5652 C CE  . LYS B 2 113 ? 230.902 174.751 192.111 1.00 82.47  ? 113  LYS C CE  1 
ATOM   5653 N NZ  . LYS B 2 113 ? 230.026 175.242 193.211 1.00 82.47  ? 113  LYS C NZ  1 
ATOM   5654 N N   . THR B 2 114 ? 231.374 180.115 192.730 1.00 79.39  ? 114  THR C N   1 
ATOM   5655 C CA  . THR B 2 114 ? 230.602 180.775 193.771 1.00 79.39  ? 114  THR C CA  1 
ATOM   5656 C C   . THR B 2 114 ? 231.505 181.714 194.557 1.00 79.39  ? 114  THR C C   1 
ATOM   5657 O O   . THR B 2 114 ? 232.723 181.526 194.616 1.00 79.39  ? 114  THR C O   1 
ATOM   5658 C CB  . THR B 2 114 ? 229.948 179.763 194.724 1.00 79.39  ? 114  THR C CB  1 
ATOM   5659 O OG1 . THR B 2 114 ? 229.190 180.461 195.719 1.00 79.39  ? 114  THR C OG1 1 
ATOM   5660 C CG2 . THR B 2 114 ? 231.005 178.910 195.406 1.00 79.39  ? 114  THR C CG2 1 
ATOM   5661 N N   . GLN B 2 115 ? 230.894 182.732 195.156 1.00 77.42  ? 115  GLN C N   1 
ATOM   5662 C CA  . GLN B 2 115 ? 231.651 183.699 195.936 1.00 77.42  ? 115  GLN C CA  1 
ATOM   5663 C C   . GLN B 2 115 ? 232.066 183.103 197.276 1.00 77.42  ? 115  GLN C C   1 
ATOM   5664 O O   . GLN B 2 115 ? 231.404 182.217 197.822 1.00 77.42  ? 115  GLN C O   1 
ATOM   5665 C CB  . GLN B 2 115 ? 230.828 184.968 196.158 1.00 77.42  ? 115  GLN C CB  1 
ATOM   5666 C CG  . GLN B 2 115 ? 230.515 185.734 194.884 1.00 77.42  ? 115  GLN C CG  1 
ATOM   5667 C CD  . GLN B 2 115 ? 229.752 187.016 195.149 1.00 77.42  ? 115  GLN C CD  1 
ATOM   5668 O OE1 . GLN B 2 115 ? 229.277 187.251 196.260 1.00 77.42  ? 115  GLN C OE1 1 
ATOM   5669 N NE2 . GLN B 2 115 ? 229.633 187.856 194.128 1.00 77.42  ? 115  GLN C NE2 1 
ATOM   5670 N N   . SER B 2 116 ? 233.180 183.604 197.805 1.00 72.33  ? 116  SER C N   1 
ATOM   5671 C CA  . SER B 2 116 ? 233.718 183.132 199.071 1.00 72.33  ? 116  SER C CA  1 
ATOM   5672 C C   . SER B 2 116 ? 234.186 184.327 199.890 1.00 72.33  ? 116  SER C C   1 
ATOM   5673 O O   . SER B 2 116 ? 234.322 185.443 199.383 1.00 72.33  ? 116  SER C O   1 
ATOM   5674 C CB  . SER B 2 116 ? 234.867 182.139 198.857 1.00 72.33  ? 116  SER C CB  1 
ATOM   5675 O OG  . SER B 2 116 ? 234.424 180.991 198.155 1.00 72.33  ? 116  SER C OG  1 
ATOM   5676 N N   . LEU B 2 117 ? 234.436 184.078 201.172 1.00 68.12  ? 117  LEU C N   1 
ATOM   5677 C CA  . LEU B 2 117 ? 234.900 185.097 202.104 1.00 68.12  ? 117  LEU C CA  1 
ATOM   5678 C C   . LEU B 2 117 ? 236.357 184.834 202.452 1.00 68.12  ? 117  LEU C C   1 
ATOM   5679 O O   . LEU B 2 117 ? 236.712 183.724 202.862 1.00 68.12  ? 117  LEU C O   1 
ATOM   5680 C CB  . LEU B 2 117 ? 234.042 185.111 203.371 1.00 68.12  ? 117  LEU C CB  1 
ATOM   5681 C CG  . LEU B 2 117 ? 234.537 185.969 204.538 1.00 68.12  ? 117  LEU C CG  1 
ATOM   5682 C CD1 . LEU B 2 117 ? 234.702 187.420 204.120 1.00 68.12  ? 117  LEU C CD1 1 
ATOM   5683 C CD2 . LEU B 2 117 ? 233.587 185.858 205.720 1.00 68.12  ? 117  LEU C CD2 1 
ATOM   5684 N N   . LEU B 2 118 ? 237.196 185.855 202.289 1.00 70.43  ? 118  LEU C N   1 
ATOM   5685 C CA  . LEU B 2 118 ? 238.627 185.758 202.558 1.00 70.43  ? 118  LEU C CA  1 
ATOM   5686 C C   . LEU B 2 118 ? 238.984 186.745 203.661 1.00 70.43  ? 118  LEU C C   1 
ATOM   5687 O O   . LEU B 2 118 ? 238.915 187.962 203.458 1.00 70.43  ? 118  LEU C O   1 
ATOM   5688 C CB  . LEU B 2 118 ? 239.442 186.031 201.295 1.00 70.43  ? 118  LEU C CB  1 
ATOM   5689 C CG  . LEU B 2 118 ? 240.959 186.098 201.484 1.00 70.43  ? 118  LEU C CG  1 
ATOM   5690 C CD1 . LEU B 2 118 ? 241.489 184.791 202.050 1.00 70.43  ? 118  LEU C CD1 1 
ATOM   5691 C CD2 . LEU B 2 118 ? 241.648 186.439 200.173 1.00 70.43  ? 118  LEU C CD2 1 
ATOM   5692 N N   . ILE B 2 119 ? 239.365 186.220 204.821 1.00 68.45  ? 119  ILE C N   1 
ATOM   5693 C CA  . ILE B 2 119 ? 239.831 187.020 205.947 1.00 68.45  ? 119  ILE C CA  1 
ATOM   5694 C C   . ILE B 2 119 ? 241.228 186.534 206.301 1.00 68.45  ? 119  ILE C C   1 
ATOM   5695 O O   . ILE B 2 119 ? 241.405 185.371 206.683 1.00 68.45  ? 119  ILE C O   1 
ATOM   5696 C CB  . ILE B 2 119 ? 238.890 186.916 207.157 1.00 68.45  ? 119  ILE C CB  1 
ATOM   5697 C CG1 . ILE B 2 119 ? 237.491 187.416 206.791 1.00 68.45  ? 119  ILE C CG1 1 
ATOM   5698 C CG2 . ILE B 2 119 ? 239.449 187.696 208.336 1.00 68.45  ? 119  ILE C CG2 1 
ATOM   5699 C CD1 . ILE B 2 119 ? 236.498 187.332 207.927 1.00 68.45  ? 119  ILE C CD1 1 
ATOM   5700 N N   . VAL B 2 120 ? 242.215 187.415 206.169 1.00 72.19  ? 120  VAL C N   1 
ATOM   5701 C CA  . VAL B 2 120 ? 243.608 187.043 206.392 1.00 72.19  ? 120  VAL C CA  1 
ATOM   5702 C C   . VAL B 2 120 ? 244.380 188.281 206.828 1.00 72.19  ? 120  VAL C C   1 
ATOM   5703 O O   . VAL B 2 120 ? 244.110 189.394 206.368 1.00 72.19  ? 120  VAL C O   1 
ATOM   5704 C CB  . VAL B 2 120 ? 244.224 186.400 205.127 1.00 72.19  ? 120  VAL C CB  1 
ATOM   5705 C CG1 . VAL B 2 120 ? 244.189 187.370 203.955 1.00 72.19  ? 120  VAL C CG1 1 
ATOM   5706 C CG2 . VAL B 2 120 ? 245.643 185.918 205.397 1.00 72.19  ? 120  VAL C CG2 1 
ATOM   5707 N N   . ASN B 2 121 ? 245.331 188.080 207.737 1.00 76.34  ? 121  ASN C N   1 
ATOM   5708 C CA  . ASN B 2 121 ? 246.220 189.133 208.216 1.00 76.34  ? 121  ASN C CA  1 
ATOM   5709 C C   . ASN B 2 121 ? 247.627 188.805 207.732 1.00 76.34  ? 121  ASN C C   1 
ATOM   5710 O O   . ASN B 2 121 ? 248.217 187.807 208.156 1.00 76.34  ? 121  ASN C O   1 
ATOM   5711 C CB  . ASN B 2 121 ? 246.166 189.239 209.740 1.00 76.34  ? 121  ASN C CB  1 
ATOM   5712 C CG  . ASN B 2 121 ? 246.824 190.502 210.265 1.00 76.34  ? 121  ASN C CG  1 
ATOM   5713 O OD1 . ASN B 2 121 ? 247.691 191.085 209.615 1.00 76.34  ? 121  ASN C OD1 1 
ATOM   5714 N ND2 . ASN B 2 121 ? 246.413 190.928 211.454 1.00 76.34  ? 121  ASN C ND2 1 
ATOM   5715 N N   . ASN B 2 122 ? 248.162 189.642 206.845 1.00 80.37  ? 122  ASN C N   1 
ATOM   5716 C CA  . ASN B 2 122 ? 249.490 189.433 206.271 1.00 80.37  ? 122  ASN C CA  1 
ATOM   5717 C C   . ASN B 2 122 ? 250.547 190.290 206.957 1.00 80.37  ? 122  ASN C C   1 
ATOM   5718 O O   . ASN B 2 122 ? 251.465 190.800 206.308 1.00 80.37  ? 122  ASN C O   1 
ATOM   5719 C CB  . ASN B 2 122 ? 249.468 189.695 204.768 1.00 80.37  ? 122  ASN C CB  1 
ATOM   5720 C CG  . ASN B 2 122 ? 249.102 191.125 204.424 1.00 80.37  ? 122  ASN C CG  1 
ATOM   5721 O OD1 . ASN B 2 122 ? 248.479 191.830 205.217 1.00 80.37  ? 122  ASN C OD1 1 
ATOM   5722 N ND2 . ASN B 2 122 ? 249.491 191.559 203.231 1.00 80.37  ? 122  ASN C ND2 1 
ATOM   5723 N N   . ALA B 2 123 ? 250.417 190.477 208.271 1.00 81.88  ? 123  ALA C N   1 
ATOM   5724 C CA  . ALA B 2 123 ? 251.347 191.183 209.149 1.00 81.88  ? 123  ALA C CA  1 
ATOM   5725 C C   . ALA B 2 123 ? 251.392 192.685 208.898 1.00 81.88  ? 123  ALA C C   1 
ATOM   5726 O O   . ALA B 2 123 ? 252.111 193.393 209.612 1.00 81.88  ? 123  ALA C O   1 
ATOM   5727 C CB  . ALA B 2 123 ? 252.776 190.625 209.065 1.00 81.88  ? 123  ALA C CB  1 
ATOM   5728 N N   . THR B 2 124 ? 250.660 193.194 207.921 1.00 81.66  ? 124  THR C N   1 
ATOM   5729 C CA  . THR B 2 124 ? 250.610 194.631 207.672 1.00 81.66  ? 124  THR C CA  1 
ATOM   5730 C C   . THR B 2 124 ? 249.190 195.173 207.624 1.00 81.66  ? 124  THR C C   1 
ATOM   5731 O O   . THR B 2 124 ? 248.955 196.298 208.069 1.00 81.66  ? 124  THR C O   1 
ATOM   5732 C CB  . THR B 2 124 ? 251.337 194.975 206.361 1.00 81.66  ? 124  THR C CB  1 
ATOM   5733 O OG1 . THR B 2 124 ? 250.836 194.151 205.302 1.00 81.66  ? 124  THR C OG1 1 
ATOM   5734 C CG2 . THR B 2 124 ? 252.836 194.758 206.507 1.00 81.66  ? 124  THR C CG2 1 
ATOM   5735 N N   . ASN B 2 125 ? 248.240 194.404 207.097 1.00 78.57  ? 125  ASN C N   1 
ATOM   5736 C CA  . ASN B 2 125 ? 246.853 194.833 207.016 1.00 78.57  ? 125  ASN C CA  1 
ATOM   5737 C C   . ASN B 2 125 ? 245.942 193.639 207.256 1.00 78.57  ? 125  ASN C C   1 
ATOM   5738 O O   . ASN B 2 125 ? 246.340 192.483 207.089 1.00 78.57  ? 125  ASN C O   1 
ATOM   5739 C CB  . ASN B 2 125 ? 246.533 195.474 205.657 1.00 78.57  ? 125  ASN C CB  1 
ATOM   5740 C CG  . ASN B 2 125 ? 247.367 196.709 205.383 1.00 78.57  ? 125  ASN C CG  1 
ATOM   5741 O OD1 . ASN B 2 125 ? 248.456 196.623 204.816 1.00 78.57  ? 125  ASN C OD1 1 
ATOM   5742 N ND2 . ASN B 2 125 ? 246.859 197.867 205.785 1.00 78.57  ? 125  ASN C ND2 1 
ATOM   5743 N N   . VAL B 2 126 ? 244.709 193.934 207.652 1.00 73.69  ? 126  VAL C N   1 
ATOM   5744 C CA  . VAL B 2 126 ? 243.673 192.924 207.838 1.00 73.69  ? 126  VAL C CA  1 
ATOM   5745 C C   . VAL B 2 126 ? 242.842 192.912 206.561 1.00 73.69  ? 126  VAL C C   1 
ATOM   5746 O O   . VAL B 2 126 ? 241.979 193.771 206.356 1.00 73.69  ? 126  VAL C O   1 
ATOM   5747 C CB  . VAL B 2 126 ? 242.817 193.206 209.075 1.00 73.69  ? 126  VAL C CB  1 
ATOM   5748 C CG1 . VAL B 2 126 ? 241.747 192.136 209.233 1.00 73.69  ? 126  VAL C CG1 1 
ATOM   5749 C CG2 . VAL B 2 126 ? 243.691 193.279 210.318 1.00 73.69  ? 126  VAL C CG2 1 
ATOM   5750 N N   . VAL B 2 127 ? 243.104 191.939 205.696 1.00 71.59  ? 127  VAL C N   1 
ATOM   5751 C CA  . VAL B 2 127 ? 242.454 191.855 204.394 1.00 71.59  ? 127  VAL C CA  1 
ATOM   5752 C C   . VAL B 2 127 ? 241.144 191.094 204.546 1.00 71.59  ? 127  VAL C C   1 
ATOM   5753 O O   . VAL B 2 127 ? 241.133 189.941 204.991 1.00 71.59  ? 127  VAL C O   1 
ATOM   5754 C CB  . VAL B 2 127 ? 243.367 191.179 203.361 1.00 71.59  ? 127  VAL C CB  1 
ATOM   5755 C CG1 . VAL B 2 127 ? 242.696 191.151 201.998 1.00 71.59  ? 127  VAL C CG1 1 
ATOM   5756 C CG2 . VAL B 2 127 ? 244.706 191.896 203.289 1.00 71.59  ? 127  VAL C CG2 1 
ATOM   5757 N N   . ILE B 2 128 ? 240.040 191.739 204.178 1.00 69.80  ? 128  ILE C N   1 
ATOM   5758 C CA  . ILE B 2 128 ? 238.713 191.130 204.198 1.00 69.80  ? 128  ILE C CA  1 
ATOM   5759 C C   . ILE B 2 128 ? 238.122 191.333 202.808 1.00 69.80  ? 128  ILE C C   1 
ATOM   5760 O O   . ILE B 2 128 ? 237.606 192.412 202.497 1.00 69.80  ? 128  ILE C O   1 
ATOM   5761 C CB  . ILE B 2 128 ? 237.805 191.727 205.278 1.00 69.80  ? 128  ILE C CB  1 
ATOM   5762 C CG1 . ILE B 2 128 ? 238.432 191.551 206.662 1.00 69.80  ? 128  ILE C CG1 1 
ATOM   5763 C CG2 . ILE B 2 128 ? 236.431 191.078 205.234 1.00 69.80  ? 128  ILE C CG2 1 
ATOM   5764 C CD1 . ILE B 2 128 ? 237.585 192.096 207.790 1.00 69.80  ? 128  ILE C CD1 1 
ATOM   5765 N N   . LYS B 2 129 ? 238.197 190.304 201.969 1.00 71.16  ? 129  LYS C N   1 
ATOM   5766 C CA  . LYS B 2 129 ? 237.704 190.365 200.601 1.00 71.16  ? 129  LYS C CA  1 
ATOM   5767 C C   . LYS B 2 129 ? 236.666 189.277 200.376 1.00 71.16  ? 129  LYS C C   1 
ATOM   5768 O O   . LYS B 2 129 ? 236.836 188.138 200.823 1.00 71.16  ? 129  LYS C O   1 
ATOM   5769 C CB  . LYS B 2 129 ? 238.847 190.211 199.591 1.00 71.16  ? 129  LYS C CB  1 
ATOM   5770 C CG  . LYS B 2 129 ? 239.876 191.326 199.644 1.00 71.16  ? 129  LYS C CG  1 
ATOM   5771 C CD  . LYS B 2 129 ? 240.967 191.119 198.607 1.00 71.16  ? 129  LYS C CD  1 
ATOM   5772 C CE  . LYS B 2 129 ? 240.394 191.106 197.200 1.00 71.16  ? 129  LYS C CE  1 
ATOM   5773 N NZ  . LYS B 2 129 ? 241.452 190.908 196.172 1.00 71.16  ? 129  LYS C NZ  1 
ATOM   5774 N N   . VAL B 2 130 ? 235.593 189.634 199.683 1.00 72.49  ? 130  VAL C N   1 
ATOM   5775 C CA  . VAL B 2 130 ? 234.517 188.703 199.347 1.00 72.49  ? 130  VAL C CA  1 
ATOM   5776 C C   . VAL B 2 130 ? 234.480 188.616 197.826 1.00 72.49  ? 130  VAL C C   1 
ATOM   5777 O O   . VAL B 2 130 ? 233.844 189.429 197.151 1.00 72.49  ? 130  VAL C O   1 
ATOM   5778 C CB  . VAL B 2 130 ? 233.166 189.138 199.919 1.00 72.49  ? 130  VAL C CB  1 
ATOM   5779 C CG1 . VAL B 2 130 ? 232.099 188.100 199.606 1.00 72.49  ? 130  VAL C CG1 1 
ATOM   5780 C CG2 . VAL B 2 130 ? 233.277 189.364 201.416 1.00 72.49  ? 130  VAL C CG2 1 
ATOM   5781 N N   . CYS B 2 131 ? 235.179 187.628 197.272 1.00 82.08  ? 131  CYS C N   1 
ATOM   5782 C CA  . CYS B 2 131 ? 235.209 187.411 195.834 1.00 82.08  ? 131  CYS C CA  1 
ATOM   5783 C C   . CYS B 2 131 ? 235.177 185.914 195.566 1.00 82.08  ? 131  CYS C C   1 
ATOM   5784 O O   . CYS B 2 131 ? 235.351 185.094 196.471 1.00 82.08  ? 131  CYS C O   1 
ATOM   5785 C CB  . CYS B 2 131 ? 236.447 188.049 195.186 1.00 82.08  ? 131  CYS C CB  1 
ATOM   5786 S SG  . CYS B 2 131 ? 237.109 189.499 196.051 1.00 82.08  ? 131  CYS C SG  1 
ATOM   5787 N N   . GLU B 2 132 ? 234.946 185.559 194.302 1.00 83.09  ? 132  GLU C N   1 
ATOM   5788 C CA  . GLU B 2 132 ? 234.949 184.157 193.883 1.00 83.09  ? 132  GLU C CA  1 
ATOM   5789 C C   . GLU B 2 132 ? 236.375 183.776 193.494 1.00 83.09  ? 132  GLU C C   1 
ATOM   5790 O O   . GLU B 2 132 ? 236.729 183.643 192.321 1.00 83.09  ? 132  GLU C O   1 
ATOM   5791 C CB  . GLU B 2 132 ? 233.958 183.931 192.747 1.00 83.09  ? 132  GLU C CB  1 
ATOM   5792 C CG  . GLU B 2 132 ? 233.980 184.994 191.662 1.00 83.09  ? 132  GLU C CG  1 
ATOM   5793 C CD  . GLU B 2 132 ? 232.981 184.716 190.557 1.00 83.09  ? 132  GLU C CD  1 
ATOM   5794 O OE1 . GLU B 2 132 ? 232.182 183.768 190.703 1.00 83.09  ? 132  GLU C OE1 1 
ATOM   5795 O OE2 . GLU B 2 132 ? 232.995 185.444 189.542 1.00 83.09  ? 132  GLU C OE2 1 
ATOM   5796 N N   . PHE B 2 133 ? 237.207 183.596 194.517 1.00 79.91  ? 133  PHE C N   1 
ATOM   5797 C CA  . PHE B 2 133 ? 238.607 183.258 194.309 1.00 79.91  ? 133  PHE C CA  1 
ATOM   5798 C C   . PHE B 2 133 ? 238.739 181.841 193.755 1.00 79.91  ? 133  PHE C C   1 
ATOM   5799 O O   . PHE B 2 133 ? 237.762 181.102 193.597 1.00 79.91  ? 133  PHE C O   1 
ATOM   5800 C CB  . PHE B 2 133 ? 239.389 183.381 195.615 1.00 79.91  ? 133  PHE C CB  1 
ATOM   5801 C CG  . PHE B 2 133 ? 239.383 184.759 196.209 1.00 79.91  ? 133  PHE C CG  1 
ATOM   5802 C CD1 . PHE B 2 133 ? 240.332 185.693 195.832 1.00 79.91  ? 133  PHE C CD1 1 
ATOM   5803 C CD2 . PHE B 2 133 ? 238.443 185.113 197.161 1.00 79.91  ? 133  PHE C CD2 1 
ATOM   5804 C CE1 . PHE B 2 133 ? 240.335 186.959 196.384 1.00 79.91  ? 133  PHE C CE1 1 
ATOM   5805 C CE2 . PHE B 2 133 ? 238.441 186.377 197.716 1.00 79.91  ? 133  PHE C CE2 1 
ATOM   5806 C CZ  . PHE B 2 133 ? 239.389 187.300 197.328 1.00 79.91  ? 133  PHE C CZ  1 
ATOM   5807 N N   . GLN B 2 134 ? 239.979 181.460 193.462 1.00 81.46  ? 134  GLN C N   1 
ATOM   5808 C CA  . GLN B 2 134 ? 240.339 180.094 193.091 1.00 81.46  ? 134  GLN C CA  1 
ATOM   5809 C C   . GLN B 2 134 ? 241.363 179.630 194.120 1.00 81.46  ? 134  GLN C C   1 
ATOM   5810 O O   . GLN B 2 134 ? 242.572 179.779 193.926 1.00 81.46  ? 134  GLN C O   1 
ATOM   5811 C CB  . GLN B 2 134 ? 240.884 180.021 191.663 1.00 81.46  ? 134  GLN C CB  1 
ATOM   5812 C CG  . GLN B 2 134 ? 241.299 178.624 191.224 1.00 81.46  ? 134  GLN C CG  1 
ATOM   5813 C CD  . GLN B 2 134 ? 240.145 177.639 191.219 1.00 81.46  ? 134  GLN C CD  1 
ATOM   5814 O OE1 . GLN B 2 134 ? 240.318 176.463 191.537 1.00 81.46  ? 134  GLN C OE1 1 
ATOM   5815 N NE2 . GLN B 2 134 ? 238.962 178.114 190.849 1.00 81.46  ? 134  GLN C NE2 1 
ATOM   5816 N N   . PHE B 2 135 ? 240.873 179.072 195.224 1.00 78.55  ? 135  PHE C N   1 
ATOM   5817 C CA  . PHE B 2 135 ? 241.737 178.670 196.321 1.00 78.55  ? 135  PHE C CA  1 
ATOM   5818 C C   . PHE B 2 135 ? 242.468 177.375 195.976 1.00 78.55  ? 135  PHE C C   1 
ATOM   5819 O O   . PHE B 2 135 ? 242.363 176.840 194.869 1.00 78.55  ? 135  PHE C O   1 
ATOM   5820 C CB  . PHE B 2 135 ? 240.927 178.519 197.606 1.00 78.55  ? 135  PHE C CB  1 
ATOM   5821 C CG  . PHE B 2 135 ? 240.221 179.774 198.028 1.00 78.55  ? 135  PHE C CG  1 
ATOM   5822 C CD1 . PHE B 2 135 ? 240.917 180.804 198.637 1.00 78.55  ? 135  PHE C CD1 1 
ATOM   5823 C CD2 . PHE B 2 135 ? 238.860 179.922 197.821 1.00 78.55  ? 135  PHE C CD2 1 
ATOM   5824 C CE1 . PHE B 2 135 ? 240.270 181.960 199.029 1.00 78.55  ? 135  PHE C CE1 1 
ATOM   5825 C CE2 . PHE B 2 135 ? 238.208 181.076 198.211 1.00 78.55  ? 135  PHE C CE2 1 
ATOM   5826 C CZ  . PHE B 2 135 ? 238.913 182.095 198.816 1.00 78.55  ? 135  PHE C CZ  1 
ATOM   5827 N N   . CYS B 2 136 ? 243.221 176.863 196.944 1.00 85.89  ? 136  CYS C N   1 
ATOM   5828 C CA  . CYS B 2 136 ? 244.025 175.666 196.768 1.00 85.89  ? 136  CYS C CA  1 
ATOM   5829 C C   . CYS B 2 136 ? 243.821 174.739 197.958 1.00 85.89  ? 136  CYS C C   1 
ATOM   5830 O O   . CYS B 2 136 ? 243.159 175.085 198.940 1.00 85.89  ? 136  CYS C O   1 
ATOM   5831 C CB  . CYS B 2 136 ? 245.507 176.019 196.596 1.00 85.89  ? 136  CYS C CB  1 
ATOM   5832 S SG  . CYS B 2 136 ? 245.837 177.022 195.129 1.00 85.89  ? 136  CYS C SG  1 
ATOM   5833 N N   . ASN B 2 137 ? 244.401 173.541 197.858 1.00 86.22  ? 137  ASN C N   1 
ATOM   5834 C CA  . ASN B 2 137 ? 244.221 172.546 198.911 1.00 86.22  ? 137  ASN C CA  1 
ATOM   5835 C C   . ASN B 2 137 ? 244.960 172.941 200.183 1.00 86.22  ? 137  ASN C C   1 
ATOM   5836 O O   . ASN B 2 137 ? 244.444 172.751 201.290 1.00 86.22  ? 137  ASN C O   1 
ATOM   5837 C CB  . ASN B 2 137 ? 244.689 171.176 198.423 1.00 86.22  ? 137  ASN C CB  1 
ATOM   5838 C CG  . ASN B 2 137 ? 243.923 170.699 197.206 1.00 86.22  ? 137  ASN C CG  1 
ATOM   5839 O OD1 . ASN B 2 137 ? 242.756 171.041 197.019 1.00 86.22  ? 137  ASN C OD1 1 
ATOM   5840 N ND2 . ASN B 2 137 ? 244.579 169.904 196.369 1.00 86.22  ? 137  ASN C ND2 1 
ATOM   5841 N N   . ASP B 2 138 ? 246.167 173.495 200.049 1.00 83.59  ? 138  ASP C N   1 
ATOM   5842 C CA  . ASP B 2 138 ? 246.999 173.890 201.184 1.00 83.59  ? 138  ASP C CA  1 
ATOM   5843 C C   . ASP B 2 138 ? 247.326 175.375 201.066 1.00 83.59  ? 138  ASP C C   1 
ATOM   5844 O O   . ASP B 2 138 ? 248.428 175.746 200.634 1.00 83.59  ? 138  ASP C O   1 
ATOM   5845 C CB  . ASP B 2 138 ? 248.276 173.054 201.256 1.00 83.59  ? 138  ASP C CB  1 
ATOM   5846 C CG  . ASP B 2 138 ? 248.007 171.606 201.615 1.00 83.59  ? 138  ASP C CG  1 
ATOM   5847 O OD1 . ASP B 2 138 ? 246.845 171.274 201.929 1.00 83.59  ? 138  ASP C OD1 1 
ATOM   5848 O OD2 . ASP B 2 138 ? 248.960 170.799 201.585 1.00 83.59  ? 138  ASP C OD2 1 
ATOM   5849 N N   . PRO B 2 139 ? 246.395 176.255 201.439 1.00 81.00  ? 139  PRO C N   1 
ATOM   5850 C CA  . PRO B 2 139 ? 246.704 177.689 201.455 1.00 81.00  ? 139  PRO C CA  1 
ATOM   5851 C C   . PRO B 2 139 ? 247.347 178.106 202.767 1.00 81.00  ? 139  PRO C C   1 
ATOM   5852 O O   . PRO B 2 139 ? 246.804 177.830 203.842 1.00 81.00  ? 139  PRO C O   1 
ATOM   5853 C CB  . PRO B 2 139 ? 245.331 178.351 201.260 1.00 81.00  ? 139  PRO C CB  1 
ATOM   5854 C CG  . PRO B 2 139 ? 244.302 177.217 201.308 1.00 81.00  ? 139  PRO C CG  1 
ATOM   5855 C CD  . PRO B 2 139 ? 245.001 176.002 201.827 1.00 81.00  ? 139  PRO C CD  1 
ATOM   5856 N N   . PHE B 2 140 ? 248.498 178.769 202.699 1.00 81.33  ? 140  PHE C N   1 
ATOM   5857 C CA  . PHE B 2 140 ? 249.229 179.133 203.904 1.00 81.33  ? 140  PHE C CA  1 
ATOM   5858 C C   . PHE B 2 140 ? 250.162 180.293 203.591 1.00 81.33  ? 140  PHE C C   1 
ATOM   5859 O O   . PHE B 2 140 ? 250.427 180.611 202.429 1.00 81.33  ? 140  PHE C O   1 
ATOM   5860 C CB  . PHE B 2 140 ? 250.015 177.940 204.461 1.00 81.33  ? 140  PHE C CB  1 
ATOM   5861 C CG  . PHE B 2 140 ? 251.144 177.491 203.575 1.00 81.33  ? 140  PHE C CG  1 
ATOM   5862 C CD1 . PHE B 2 140 ? 252.443 177.907 203.820 1.00 81.33  ? 140  PHE C CD1 1 
ATOM   5863 C CD2 . PHE B 2 140 ? 250.907 176.656 202.496 1.00 81.33  ? 140  PHE C CD2 1 
ATOM   5864 C CE1 . PHE B 2 140 ? 253.483 177.498 203.007 1.00 81.33  ? 140  PHE C CE1 1 
ATOM   5865 C CE2 . PHE B 2 140 ? 251.943 176.244 201.680 1.00 81.33  ? 140  PHE C CE2 1 
ATOM   5866 C CZ  . PHE B 2 140 ? 253.233 176.666 201.937 1.00 81.33  ? 140  PHE C CZ  1 
ATOM   5867 N N   . LEU B 2 141 ? 250.657 180.921 204.652 1.00 82.51  ? 141  LEU C N   1 
ATOM   5868 C CA  . LEU B 2 141 ? 251.676 181.954 204.567 1.00 82.51  ? 141  LEU C CA  1 
ATOM   5869 C C   . LEU B 2 141 ? 253.000 181.404 205.083 1.00 82.51  ? 141  LEU C C   1 
ATOM   5870 O O   . LEU B 2 141 ? 253.049 180.364 205.745 1.00 82.51  ? 141  LEU C O   1 
ATOM   5871 C CB  . LEU B 2 141 ? 251.274 183.202 205.363 1.00 82.51  ? 141  LEU C CB  1 
ATOM   5872 C CG  . LEU B 2 141 ? 250.155 184.091 204.808 1.00 82.51  ? 141  LEU C CG  1 
ATOM   5873 C CD1 . LEU B 2 141 ? 248.777 183.484 205.040 1.00 82.51  ? 141  LEU C CD1 1 
ATOM   5874 C CD2 . LEU B 2 141 ? 250.235 185.487 205.409 1.00 82.51  ? 141  LEU C CD2 1 
ATOM   5875 N N   . GLY B 2 142 ? 254.076 182.112 204.775 1.00 90.06  ? 142  GLY C N   1 
ATOM   5876 C CA  . GLY B 2 142 ? 255.404 181.658 205.144 1.00 90.06  ? 142  GLY C CA  1 
ATOM   5877 C C   . GLY B 2 142 ? 256.271 182.801 205.623 1.00 90.06  ? 142  GLY C C   1 
ATOM   5878 O O   . GLY B 2 142 ? 256.108 183.951 205.210 1.00 90.06  ? 142  GLY C O   1 
ATOM   5879 N N   . VAL B 2 143 ? 257.204 182.466 206.512 1.00 95.32  ? 143  VAL C N   1 
ATOM   5880 C CA  . VAL B 2 143 ? 258.202 183.404 207.003 1.00 95.32  ? 143  VAL C CA  1 
ATOM   5881 C C   . VAL B 2 143 ? 259.579 182.829 206.700 1.00 95.32  ? 143  VAL C C   1 
ATOM   5882 O O   . VAL B 2 143 ? 259.739 181.635 206.437 1.00 95.32  ? 143  VAL C O   1 
ATOM   5883 C CB  . VAL B 2 143 ? 258.050 183.693 208.511 1.00 95.32  ? 143  VAL C CB  1 
ATOM   5884 C CG1 . VAL B 2 143 ? 256.607 184.036 208.849 1.00 95.32  ? 143  VAL C CG1 1 
ATOM   5885 C CG2 . VAL B 2 143 ? 258.528 182.509 209.331 1.00 95.32  ? 143  VAL C CG2 1 
ATOM   5886 N N   . TYR B 2 144 ? 260.584 183.702 206.735 1.00 109.04 ? 144  TYR C N   1 
ATOM   5887 C CA  . TYR B 2 144 ? 261.960 183.321 206.426 1.00 109.04 ? 144  TYR C CA  1 
ATOM   5888 C C   . TYR B 2 144 ? 262.873 183.849 207.523 1.00 109.04 ? 144  TYR C C   1 
ATOM   5889 O O   . TYR B 2 144 ? 263.043 185.065 207.663 1.00 109.04 ? 144  TYR C O   1 
ATOM   5890 C CB  . TYR B 2 144 ? 262.384 183.855 205.057 1.00 109.04 ? 144  TYR C CB  1 
ATOM   5891 C CG  . TYR B 2 144 ? 263.725 183.339 204.588 1.00 109.04 ? 144  TYR C CG  1 
ATOM   5892 C CD1 . TYR B 2 144 ? 263.834 182.110 203.952 1.00 109.04 ? 144  TYR C CD1 1 
ATOM   5893 C CD2 . TYR B 2 144 ? 264.882 184.082 204.780 1.00 109.04 ? 144  TYR C CD2 1 
ATOM   5894 C CE1 . TYR B 2 144 ? 265.057 181.634 203.521 1.00 109.04 ? 144  TYR C CE1 1 
ATOM   5895 C CE2 . TYR B 2 144 ? 266.110 183.615 204.352 1.00 109.04 ? 144  TYR C CE2 1 
ATOM   5896 C CZ  . TYR B 2 144 ? 266.192 182.390 203.723 1.00 109.04 ? 144  TYR C CZ  1 
ATOM   5897 O OH  . TYR B 2 144 ? 267.413 181.921 203.296 1.00 109.04 ? 144  TYR C OH  1 
ATOM   5898 N N   . TYR B 2 145 ? 263.464 182.937 208.296 1.00 112.13 ? 145  TYR C N   1 
ATOM   5899 C CA  . TYR B 2 145 ? 264.403 183.300 209.357 1.00 112.13 ? 145  TYR C CA  1 
ATOM   5900 C C   . TYR B 2 145 ? 265.734 183.666 208.707 1.00 112.13 ? 145  TYR C C   1 
ATOM   5901 O O   . TYR B 2 145 ? 266.661 182.860 208.597 1.00 112.13 ? 145  TYR C O   1 
ATOM   5902 C CB  . TYR B 2 145 ? 264.555 182.157 210.355 1.00 112.13 ? 145  TYR C CB  1 
ATOM   5903 C CG  . TYR B 2 145 ? 265.290 182.522 211.628 1.00 112.13 ? 145  TYR C CG  1 
ATOM   5904 C CD1 . TYR B 2 145 ? 265.620 183.841 211.915 1.00 112.13 ? 145  TYR C CD1 1 
ATOM   5905 C CD2 . TYR B 2 145 ? 265.658 181.543 212.541 1.00 112.13 ? 145  TYR C CD2 1 
ATOM   5906 C CE1 . TYR B 2 145 ? 266.292 184.173 213.076 1.00 112.13 ? 145  TYR C CE1 1 
ATOM   5907 C CE2 . TYR B 2 145 ? 266.330 181.866 213.704 1.00 112.13 ? 145  TYR C CE2 1 
ATOM   5908 C CZ  . TYR B 2 145 ? 266.645 183.182 213.966 1.00 112.13 ? 145  TYR C CZ  1 
ATOM   5909 O OH  . TYR B 2 145 ? 267.314 183.508 215.123 1.00 112.13 ? 145  TYR C OH  1 
ATOM   5910 N N   . HIS B 2 146 ? 265.824 184.919 208.267 1.00 121.63 ? 146  HIS C N   1 
ATOM   5911 C CA  . HIS B 2 146 ? 267.018 185.414 207.591 1.00 121.63 ? 146  HIS C CA  1 
ATOM   5912 C C   . HIS B 2 146 ? 268.027 185.867 208.639 1.00 121.63 ? 146  HIS C C   1 
ATOM   5913 O O   . HIS B 2 146 ? 267.808 186.865 209.333 1.00 121.63 ? 146  HIS C O   1 
ATOM   5914 C CB  . HIS B 2 146 ? 266.660 186.551 206.640 1.00 121.63 ? 146  HIS C CB  1 
ATOM   5915 C CG  . HIS B 2 146 ? 267.681 186.789 205.572 1.00 121.63 ? 146  HIS C CG  1 
ATOM   5916 N ND1 . HIS B 2 146 ? 267.546 187.775 204.619 1.00 121.63 ? 146  HIS C ND1 1 
ATOM   5917 C CD2 . HIS B 2 146 ? 268.851 186.164 205.302 1.00 121.63 ? 146  HIS C CD2 1 
ATOM   5918 C CE1 . HIS B 2 146 ? 268.590 187.749 203.810 1.00 121.63 ? 146  HIS C CE1 1 
ATOM   5919 N NE2 . HIS B 2 146 ? 269.397 186.780 204.203 1.00 121.63 ? 146  HIS C NE2 1 
ATOM   5920 N N   . LYS B 2 147 ? 269.135 185.136 208.754 1.00 120.34 ? 147  LYS C N   1 
ATOM   5921 C CA  . LYS B 2 147 ? 270.165 185.453 209.734 1.00 120.34 ? 147  LYS C CA  1 
ATOM   5922 C C   . LYS B 2 147 ? 271.048 186.621 209.312 1.00 120.34 ? 147  LYS C C   1 
ATOM   5923 O O   . LYS B 2 147 ? 271.837 187.107 210.129 1.00 120.34 ? 147  LYS C O   1 
ATOM   5924 C CB  . LYS B 2 147 ? 271.032 184.217 209.994 1.00 120.34 ? 147  LYS C CB  1 
ATOM   5925 C CG  . LYS B 2 147 ? 271.722 184.206 211.349 1.00 120.34 ? 147  LYS C CG  1 
ATOM   5926 C CD  . LYS B 2 147 ? 270.709 184.154 212.480 1.00 120.34 ? 147  LYS C CD  1 
ATOM   5927 C CE  . LYS B 2 147 ? 269.880 182.882 212.421 1.00 120.34 ? 147  LYS C CE  1 
ATOM   5928 N NZ  . LYS B 2 147 ? 270.727 181.663 212.540 1.00 120.34 ? 147  LYS C NZ  1 
ATOM   5929 N N   . ASN B 2 148 ? 270.932 187.086 208.066 1.00 124.04 ? 148  ASN C N   1 
ATOM   5930 C CA  . ASN B 2 148 ? 271.773 188.186 207.603 1.00 124.04 ? 148  ASN C CA  1 
ATOM   5931 C C   . ASN B 2 148 ? 271.399 189.493 208.290 1.00 124.04 ? 148  ASN C C   1 
ATOM   5932 O O   . ASN B 2 148 ? 272.261 190.182 208.848 1.00 124.04 ? 148  ASN C O   1 
ATOM   5933 C CB  . ASN B 2 148 ? 271.666 188.323 206.084 1.00 124.04 ? 148  ASN C CB  1 
ATOM   5934 C CG  . ASN B 2 148 ? 272.466 189.493 205.547 1.00 124.04 ? 148  ASN C CG  1 
ATOM   5935 O OD1 . ASN B 2 148 ? 271.948 190.600 205.400 1.00 124.04 ? 148  ASN C OD1 1 
ATOM   5936 N ND2 . ASN B 2 148 ? 273.738 189.253 205.250 1.00 124.04 ? 148  ASN C ND2 1 
ATOM   5937 N N   . ASN B 2 149 ? 270.117 189.853 208.260 1.00 123.00 ? 149  ASN C N   1 
ATOM   5938 C CA  . ASN B 2 149 ? 269.635 191.081 208.878 1.00 123.00 ? 149  ASN C CA  1 
ATOM   5939 C C   . ASN B 2 149 ? 268.864 190.826 210.166 1.00 123.00 ? 149  ASN C C   1 
ATOM   5940 O O   . ASN B 2 149 ? 268.262 191.758 210.710 1.00 123.00 ? 149  ASN C O   1 
ATOM   5941 C CB  . ASN B 2 149 ? 268.766 191.868 207.893 1.00 123.00 ? 149  ASN C CB  1 
ATOM   5942 C CG  . ASN B 2 149 ? 268.450 191.082 206.635 1.00 123.00 ? 149  ASN C CG  1 
ATOM   5943 O OD1 . ASN B 2 149 ? 268.462 189.851 206.634 1.00 123.00 ? 149  ASN C OD1 1 
ATOM   5944 N ND2 . ASN B 2 149 ? 268.164 191.796 205.551 1.00 123.00 ? 149  ASN C ND2 1 
ATOM   5945 N N   . LYS B 2 150 ? 268.868 189.587 210.664 1.00 123.14 ? 150  LYS C N   1 
ATOM   5946 C CA  . LYS B 2 150 ? 268.186 189.219 211.907 1.00 123.14 ? 150  LYS C CA  1 
ATOM   5947 C C   . LYS B 2 150 ? 266.698 189.561 211.862 1.00 123.14 ? 150  LYS C C   1 
ATOM   5948 O O   . LYS B 2 150 ? 266.086 189.852 212.892 1.00 123.14 ? 150  LYS C O   1 
ATOM   5949 C CB  . LYS B 2 150 ? 268.846 189.880 213.121 1.00 123.14 ? 150  LYS C CB  1 
ATOM   5950 C CG  . LYS B 2 150 ? 270.353 189.691 213.194 1.00 123.14 ? 150  LYS C CG  1 
ATOM   5951 C CD  . LYS B 2 150 ? 270.729 188.225 213.330 1.00 123.14 ? 150  LYS C CD  1 
ATOM   5952 C CE  . LYS B 2 150 ? 272.236 188.057 213.433 1.00 123.14 ? 150  LYS C CE  1 
ATOM   5953 N NZ  . LYS B 2 150 ? 272.631 186.633 213.610 1.00 123.14 ? 150  LYS C NZ  1 
ATOM   5954 N N   . SER B 2 151 ? 266.107 189.526 210.671 1.00 119.88 ? 151  SER C N   1 
ATOM   5955 C CA  . SER B 2 151 ? 264.706 189.866 210.482 1.00 119.88 ? 151  SER C CA  1 
ATOM   5956 C C   . SER B 2 151 ? 263.999 188.730 209.756 1.00 119.88 ? 151  SER C C   1 
ATOM   5957 O O   . SER B 2 151 ? 264.624 187.919 209.068 1.00 119.88 ? 151  SER C O   1 
ATOM   5958 C CB  . SER B 2 151 ? 264.545 191.175 209.696 1.00 119.88 ? 151  SER C CB  1 
ATOM   5959 O OG  . SER B 2 151 ? 265.161 191.086 208.424 1.00 119.88 ? 151  SER C OG  1 
ATOM   5960 N N   . TRP B 2 152 ? 262.678 188.683 209.919 1.00 105.88 ? 152  TRP C N   1 
ATOM   5961 C CA  . TRP B 2 152 ? 261.870 187.631 209.309 1.00 105.88 ? 152  TRP C CA  1 
ATOM   5962 C C   . TRP B 2 152 ? 261.326 188.062 207.949 1.00 105.88 ? 152  TRP C C   1 
ATOM   5963 O O   . TRP B 2 152 ? 261.628 187.433 206.929 1.00 105.88 ? 152  TRP C O   1 
ATOM   5964 C CB  . TRP B 2 152 ? 260.734 187.234 210.256 1.00 105.88 ? 152  TRP C CB  1 
ATOM   5965 C CG  . TRP B 2 152 ? 261.224 186.704 211.569 1.00 105.88 ? 152  TRP C CG  1 
ATOM   5966 C CD1 . TRP B 2 152 ? 261.644 187.435 212.642 1.00 105.88 ? 152  TRP C CD1 1 
ATOM   5967 C CD2 . TRP B 2 152 ? 261.349 185.328 211.949 1.00 105.88 ? 152  TRP C CD2 1 
ATOM   5968 N NE1 . TRP B 2 152 ? 262.022 186.601 213.665 1.00 105.88 ? 152  TRP C NE1 1 
ATOM   5969 C CE2 . TRP B 2 152 ? 261.850 185.302 213.265 1.00 105.88 ? 152  TRP C CE2 1 
ATOM   5970 C CE3 . TRP B 2 152 ? 261.085 184.116 211.303 1.00 105.88 ? 152  TRP C CE3 1 
ATOM   5971 C CZ2 . TRP B 2 152 ? 262.092 184.112 213.948 1.00 105.88 ? 152  TRP C CZ2 1 
ATOM   5972 C CZ3 . TRP B 2 152 ? 261.327 182.936 211.984 1.00 105.88 ? 152  TRP C CZ3 1 
ATOM   5973 C CH2 . TRP B 2 152 ? 261.825 182.943 213.292 1.00 105.88 ? 152  TRP C CH2 1 
ATOM   5974 N N   . MET B 2 153 ? 260.538 189.136 207.921 1.00 113.17 ? 153  MET C N   1 
ATOM   5975 C CA  . MET B 2 153 ? 259.997 189.705 206.685 1.00 113.17 ? 153  MET C CA  1 
ATOM   5976 C C   . MET B 2 153 ? 259.268 188.635 205.866 1.00 113.17 ? 153  MET C C   1 
ATOM   5977 O O   . MET B 2 153 ? 259.699 188.224 204.788 1.00 113.17 ? 153  MET C O   1 
ATOM   5978 C CB  . MET B 2 153 ? 261.106 190.378 205.869 1.00 113.17 ? 153  MET C CB  1 
ATOM   5979 C CG  . MET B 2 153 ? 260.603 191.253 204.731 1.00 113.17 ? 153  MET C CG  1 
ATOM   5980 S SD  . MET B 2 153 ? 261.943 192.018 203.798 1.00 113.17 ? 153  MET C SD  1 
ATOM   5981 C CE  . MET B 2 153 ? 262.751 192.968 205.083 1.00 113.17 ? 153  MET C CE  1 
ATOM   5982 N N   . GLU B 2 154 ? 258.158 188.172 206.442 1.00 101.10 ? 154  GLU C N   1 
ATOM   5983 C CA  . GLU B 2 154 ? 257.373 187.099 205.844 1.00 101.10 ? 154  GLU C CA  1 
ATOM   5984 C C   . GLU B 2 154 ? 257.017 187.420 204.397 1.00 101.10 ? 154  GLU C C   1 
ATOM   5985 O O   . GLU B 2 154 ? 256.841 188.582 204.017 1.00 101.10 ? 154  GLU C O   1 
ATOM   5986 C CB  . GLU B 2 154 ? 256.099 186.859 206.660 1.00 101.10 ? 154  GLU C CB  1 
ATOM   5987 C CG  . GLU B 2 154 ? 255.159 188.056 206.745 1.00 101.10 ? 154  GLU C CG  1 
ATOM   5988 C CD  . GLU B 2 154 ? 254.168 188.109 205.597 1.00 101.10 ? 154  GLU C CD  1 
ATOM   5989 O OE1 . GLU B 2 154 ? 253.964 187.068 204.937 1.00 101.10 ? 154  GLU C OE1 1 
ATOM   5990 O OE2 . GLU B 2 154 ? 253.597 189.192 205.353 1.00 101.10 ? 154  GLU C OE2 1 
ATOM   5991 N N   . SER B 2 155 ? 256.913 186.371 203.587 1.00 96.50  ? 155  SER C N   1 
ATOM   5992 C CA  . SER B 2 155 ? 256.598 186.504 202.172 1.00 96.50  ? 155  SER C CA  1 
ATOM   5993 C C   . SER B 2 155 ? 255.905 185.225 201.715 1.00 96.50  ? 155  SER C C   1 
ATOM   5994 O O   . SER B 2 155 ? 255.468 184.410 202.533 1.00 96.50  ? 155  SER C O   1 
ATOM   5995 C CB  . SER B 2 155 ? 257.865 186.801 201.361 1.00 96.50  ? 155  SER C CB  1 
ATOM   5996 O OG  . SER B 2 155 ? 258.818 185.763 201.506 1.00 96.50  ? 155  SER C OG  1 
ATOM   5997 N N   . GLU B 2 156 ? 255.802 185.056 200.396 1.00 97.13  ? 156  GLU C N   1 
ATOM   5998 C CA  . GLU B 2 156 ? 255.180 183.882 199.783 1.00 97.13  ? 156  GLU C CA  1 
ATOM   5999 C C   . GLU B 2 156 ? 253.733 183.720 200.254 1.00 97.13  ? 156  GLU C C   1 
ATOM   6000 O O   . GLU B 2 156 ? 253.353 182.724 200.872 1.00 97.13  ? 156  GLU C O   1 
ATOM   6001 C CB  . GLU B 2 156 ? 256.001 182.617 200.062 1.00 97.13  ? 156  GLU C CB  1 
ATOM   6002 C CG  . GLU B 2 156 ? 257.459 182.711 199.636 1.00 97.13  ? 156  GLU C CG  1 
ATOM   6003 C CD  . GLU B 2 156 ? 257.629 182.806 198.131 1.00 97.13  ? 156  GLU C CD  1 
ATOM   6004 O OE1 . GLU B 2 156 ? 256.713 182.381 197.395 1.00 97.13  ? 156  GLU C OE1 1 
ATOM   6005 O OE2 . GLU B 2 156 ? 258.681 183.308 197.682 1.00 97.13  ? 156  GLU C OE2 1 
ATOM   6006 N N   . PHE B 2 157 ? 252.927 184.732 199.948 1.00 87.72  ? 157  PHE C N   1 
ATOM   6007 C CA  . PHE B 2 157 ? 251.503 184.720 200.278 1.00 87.72  ? 157  PHE C CA  1 
ATOM   6008 C C   . PHE B 2 157 ? 250.790 183.781 199.315 1.00 87.72  ? 157  PHE C C   1 
ATOM   6009 O O   . PHE B 2 157 ? 250.433 184.165 198.200 1.00 87.72  ? 157  PHE C O   1 
ATOM   6010 C CB  . PHE B 2 157 ? 250.934 186.132 200.205 1.00 87.72  ? 157  PHE C CB  1 
ATOM   6011 C CG  . PHE B 2 157 ? 249.486 186.226 200.592 1.00 87.72  ? 157  PHE C CG  1 
ATOM   6012 C CD1 . PHE B 2 157 ? 249.114 186.280 201.925 1.00 87.72  ? 157  PHE C CD1 1 
ATOM   6013 C CD2 . PHE B 2 157 ? 248.497 186.273 199.624 1.00 87.72  ? 157  PHE C CD2 1 
ATOM   6014 C CE1 . PHE B 2 157 ? 247.784 186.370 202.285 1.00 87.72  ? 157  PHE C CE1 1 
ATOM   6015 C CE2 . PHE B 2 157 ? 247.165 186.364 199.978 1.00 87.72  ? 157  PHE C CE2 1 
ATOM   6016 C CZ  . PHE B 2 157 ? 246.808 186.413 201.310 1.00 87.72  ? 157  PHE C CZ  1 
ATOM   6017 N N   . ARG B 2 158 ? 250.582 182.539 199.742 1.00 87.21  ? 158  ARG C N   1 
ATOM   6018 C CA  . ARG B 2 158 ? 249.987 181.497 198.908 1.00 87.21  ? 158  ARG C CA  1 
ATOM   6019 C C   . ARG B 2 158 ? 248.619 181.148 199.489 1.00 87.21  ? 158  ARG C C   1 
ATOM   6020 O O   . ARG B 2 158 ? 248.486 180.226 200.295 1.00 87.21  ? 158  ARG C O   1 
ATOM   6021 C CB  . ARG B 2 158 ? 250.895 180.273 198.839 1.00 87.21  ? 158  ARG C CB  1 
ATOM   6022 C CG  . ARG B 2 158 ? 252.336 180.593 198.482 1.00 87.21  ? 158  ARG C CG  1 
ATOM   6023 C CD  . ARG B 2 158 ? 253.204 179.348 198.516 1.00 87.21  ? 158  ARG C CD  1 
ATOM   6024 N NE  . ARG B 2 158 ? 254.609 179.655 198.266 1.00 87.21  ? 158  ARG C NE  1 
ATOM   6025 C CZ  . ARG B 2 158 ? 255.161 179.694 197.058 1.00 87.21  ? 158  ARG C CZ  1 
ATOM   6026 N NH1 . ARG B 2 158 ? 256.448 179.983 196.924 1.00 87.21  ? 158  ARG C NH1 1 
ATOM   6027 N NH2 . ARG B 2 158 ? 254.426 179.446 195.983 1.00 87.21  ? 158  ARG C NH2 1 
ATOM   6028 N N   . VAL B 2 159 ? 247.597 181.894 199.071 1.00 81.86  ? 159  VAL C N   1 
ATOM   6029 C CA  . VAL B 2 159 ? 246.234 181.655 199.530 1.00 81.86  ? 159  VAL C CA  1 
ATOM   6030 C C   . VAL B 2 159 ? 245.319 181.460 198.329 1.00 81.86  ? 159  VAL C C   1 
ATOM   6031 O O   . VAL B 2 159 ? 244.646 180.430 198.207 1.00 81.86  ? 159  VAL C O   1 
ATOM   6032 C CB  . VAL B 2 159 ? 245.735 182.806 200.422 1.00 81.86  ? 159  VAL C CB  1 
ATOM   6033 C CG1 . VAL B 2 159 ? 244.255 182.638 200.722 1.00 81.86  ? 159  VAL C CG1 1 
ATOM   6034 C CG2 . VAL B 2 159 ? 246.538 182.863 201.712 1.00 81.86  ? 159  VAL C CG2 1 
ATOM   6035 N N   . TYR B 2 160 ? 245.290 182.444 197.435 1.00 80.70  ? 160  TYR C N   1 
ATOM   6036 C CA  . TYR B 2 160 ? 244.443 182.404 196.252 1.00 80.70  ? 160  TYR C CA  1 
ATOM   6037 C C   . TYR B 2 160 ? 245.283 182.672 195.014 1.00 80.70  ? 160  TYR C C   1 
ATOM   6038 O O   . TYR B 2 160 ? 246.220 183.475 195.049 1.00 80.70  ? 160  TYR C O   1 
ATOM   6039 C CB  . TYR B 2 160 ? 243.299 183.425 196.346 1.00 80.70  ? 160  TYR C CB  1 
ATOM   6040 C CG  . TYR B 2 160 ? 243.755 184.863 196.466 1.00 80.70  ? 160  TYR C CG  1 
ATOM   6041 C CD1 . TYR B 2 160 ? 243.858 185.675 195.344 1.00 80.70  ? 160  TYR C CD1 1 
ATOM   6042 C CD2 . TYR B 2 160 ? 244.076 185.409 197.701 1.00 80.70  ? 160  TYR C CD2 1 
ATOM   6043 C CE1 . TYR B 2 160 ? 244.272 186.989 195.449 1.00 80.70  ? 160  TYR C CE1 1 
ATOM   6044 C CE2 . TYR B 2 160 ? 244.490 186.722 197.816 1.00 80.70  ? 160  TYR C CE2 1 
ATOM   6045 C CZ  . TYR B 2 160 ? 244.587 187.507 196.687 1.00 80.70  ? 160  TYR C CZ  1 
ATOM   6046 O OH  . TYR B 2 160 ? 244.999 188.815 196.798 1.00 80.70  ? 160  TYR C OH  1 
ATOM   6047 N N   . SER B 2 161 ? 244.942 181.994 193.920 1.00 82.26  ? 161  SER C N   1 
ATOM   6048 C CA  . SER B 2 161 ? 245.645 182.146 192.653 1.00 82.26  ? 161  SER C CA  1 
ATOM   6049 C C   . SER B 2 161 ? 244.929 183.075 191.683 1.00 82.26  ? 161  SER C C   1 
ATOM   6050 O O   . SER B 2 161 ? 245.573 183.924 191.059 1.00 82.26  ? 161  SER C O   1 
ATOM   6051 C CB  . SER B 2 161 ? 245.845 180.779 191.992 1.00 82.26  ? 161  SER C CB  1 
ATOM   6052 O OG  . SER B 2 161 ? 244.601 180.147 191.742 1.00 82.26  ? 161  SER C OG  1 
ATOM   6053 N N   . SER B 2 162 ? 243.614 182.936 191.540 1.00 82.29  ? 162  SER C N   1 
ATOM   6054 C CA  . SER B 2 162 ? 242.826 183.746 190.619 1.00 82.29  ? 162  SER C CA  1 
ATOM   6055 C C   . SER B 2 162 ? 241.748 184.481 191.401 1.00 82.29  ? 162  SER C C   1 
ATOM   6056 O O   . SER B 2 162 ? 240.870 183.848 191.997 1.00 82.29  ? 162  SER C O   1 
ATOM   6057 C CB  . SER B 2 162 ? 242.201 182.880 189.523 1.00 82.29  ? 162  SER C CB  1 
ATOM   6058 O OG  . SER B 2 162 ? 243.198 182.197 188.783 1.00 82.29  ? 162  SER C OG  1 
ATOM   6059 N N   . ALA B 2 163 ? 241.815 185.808 191.397 1.00 83.49  ? 163  ALA C N   1 
ATOM   6060 C CA  . ALA B 2 163 ? 240.828 186.657 192.049 1.00 83.49  ? 163  ALA C CA  1 
ATOM   6061 C C   . ALA B 2 163 ? 240.043 187.416 190.989 1.00 83.49  ? 163  ALA C C   1 
ATOM   6062 O O   . ALA B 2 163 ? 240.636 188.068 190.122 1.00 83.49  ? 163  ALA C O   1 
ATOM   6063 C CB  . ALA B 2 163 ? 241.497 187.635 193.018 1.00 83.49  ? 163  ALA C CB  1 
ATOM   6064 N N   . ASN B 2 164 ? 238.716 187.332 191.058 1.00 87.81  ? 164  ASN C N   1 
ATOM   6065 C CA  . ASN B 2 164 ? 237.866 187.967 190.063 1.00 87.81  ? 164  ASN C CA  1 
ATOM   6066 C C   . ASN B 2 164 ? 236.494 188.239 190.662 1.00 87.81  ? 164  ASN C C   1 
ATOM   6067 O O   . ASN B 2 164 ? 236.026 187.506 191.537 1.00 87.81  ? 164  ASN C O   1 
ATOM   6068 C CB  . ASN B 2 164 ? 237.735 187.096 188.806 1.00 87.81  ? 164  ASN C CB  1 
ATOM   6069 C CG  . ASN B 2 164 ? 236.922 187.763 187.714 1.00 87.81  ? 164  ASN C CG  1 
ATOM   6070 O OD1 . ASN B 2 164 ? 235.704 187.598 187.642 1.00 87.81  ? 164  ASN C OD1 1 
ATOM   6071 N ND2 . ASN B 2 164 ? 237.594 188.523 186.857 1.00 87.81  ? 164  ASN C ND2 1 
ATOM   6072 N N   . ASN B 2 165 ? 235.861 189.310 190.179 1.00 86.52  ? 165  ASN C N   1 
ATOM   6073 C CA  . ASN B 2 165 ? 234.492 189.677 190.546 1.00 86.52  ? 165  ASN C CA  1 
ATOM   6074 C C   . ASN B 2 165 ? 234.355 189.875 192.058 1.00 86.52  ? 165  ASN C C   1 
ATOM   6075 O O   . ASN B 2 165 ? 233.644 189.145 192.751 1.00 86.52  ? 165  ASN C O   1 
ATOM   6076 C CB  . ASN B 2 165 ? 233.490 188.638 190.031 1.00 86.52  ? 165  ASN C CB  1 
ATOM   6077 C CG  . ASN B 2 165 ? 232.057 189.127 190.101 1.00 86.52  ? 165  ASN C CG  1 
ATOM   6078 O OD1 . ASN B 2 165 ? 231.804 190.329 190.179 1.00 86.52  ? 165  ASN C OD1 1 
ATOM   6079 N ND2 . ASN B 2 165 ? 231.110 188.198 190.072 1.00 86.52  ? 165  ASN C ND2 1 
ATOM   6080 N N   . CYS B 2 166 ? 235.059 190.885 192.560 1.00 79.61  ? 166  CYS C N   1 
ATOM   6081 C CA  . CYS B 2 166 ? 235.020 191.224 193.976 1.00 79.61  ? 166  CYS C CA  1 
ATOM   6082 C C   . CYS B 2 166 ? 233.835 192.138 194.264 1.00 79.61  ? 166  CYS C C   1 
ATOM   6083 O O   . CYS B 2 166 ? 233.591 193.101 193.530 1.00 79.61  ? 166  CYS C O   1 
ATOM   6084 C CB  . CYS B 2 166 ? 236.325 191.894 194.406 1.00 79.61  ? 166  CYS C CB  1 
ATOM   6085 S SG  . CYS B 2 166 ? 237.710 190.749 194.568 1.00 79.61  ? 166  CYS C SG  1 
ATOM   6086 N N   . THR B 2 167 ? 233.104 191.832 195.336 1.00 71.51  ? 167  THR C N   1 
ATOM   6087 C CA  . THR B 2 167 ? 231.959 192.627 195.754 1.00 71.51  ? 167  THR C CA  1 
ATOM   6088 C C   . THR B 2 167 ? 232.156 193.311 197.099 1.00 71.51  ? 167  THR C C   1 
ATOM   6089 O O   . THR B 2 167 ? 231.361 194.191 197.447 1.00 71.51  ? 167  THR C O   1 
ATOM   6090 C CB  . THR B 2 167 ? 230.693 191.758 195.813 1.00 71.51  ? 167  THR C CB  1 
ATOM   6091 O OG1 . THR B 2 167 ? 229.603 192.530 196.332 1.00 71.51  ? 167  THR C OG1 1 
ATOM   6092 C CG2 . THR B 2 167 ? 230.914 190.550 196.706 1.00 71.51  ? 167  THR C CG2 1 
ATOM   6093 N N   . PHE B 2 168 ? 233.182 192.936 197.859 1.00 67.78  ? 168  PHE C N   1 
ATOM   6094 C CA  . PHE B 2 168 ? 233.455 193.554 199.147 1.00 67.78  ? 168  PHE C CA  1 
ATOM   6095 C C   . PHE B 2 168 ? 234.955 193.523 199.398 1.00 67.78  ? 168  PHE C C   1 
ATOM   6096 O O   . PHE B 2 168 ? 235.622 192.534 199.082 1.00 67.78  ? 168  PHE C O   1 
ATOM   6097 C CB  . PHE B 2 168 ? 232.707 192.842 200.281 1.00 67.78  ? 168  PHE C CB  1 
ATOM   6098 C CG  . PHE B 2 168 ? 232.889 193.482 201.627 1.00 67.78  ? 168  PHE C CG  1 
ATOM   6099 C CD1 . PHE B 2 168 ? 233.849 193.015 202.509 1.00 67.78  ? 168  PHE C CD1 1 
ATOM   6100 C CD2 . PHE B 2 168 ? 232.098 194.551 202.012 1.00 67.78  ? 168  PHE C CD2 1 
ATOM   6101 C CE1 . PHE B 2 168 ? 234.017 193.602 203.748 1.00 67.78  ? 168  PHE C CE1 1 
ATOM   6102 C CE2 . PHE B 2 168 ? 232.261 195.143 203.250 1.00 67.78  ? 168  PHE C CE2 1 
ATOM   6103 C CZ  . PHE B 2 168 ? 233.222 194.668 204.119 1.00 67.78  ? 168  PHE C CZ  1 
ATOM   6104 N N   . GLU B 2 169 ? 235.476 194.608 199.965 1.00 72.55  ? 169  GLU C N   1 
ATOM   6105 C CA  . GLU B 2 169 ? 236.900 194.718 200.243 1.00 72.55  ? 169  GLU C CA  1 
ATOM   6106 C C   . GLU B 2 169 ? 237.106 195.661 201.419 1.00 72.55  ? 169  GLU C C   1 
ATOM   6107 O O   . GLU B 2 169 ? 236.483 196.724 201.486 1.00 72.55  ? 169  GLU C O   1 
ATOM   6108 C CB  . GLU B 2 169 ? 237.673 195.218 199.017 1.00 72.55  ? 169  GLU C CB  1 
ATOM   6109 C CG  . GLU B 2 169 ? 239.175 195.309 199.223 1.00 72.55  ? 169  GLU C CG  1 
ATOM   6110 C CD  . GLU B 2 169 ? 239.905 195.783 197.982 1.00 72.55  ? 169  GLU C CD  1 
ATOM   6111 O OE1 . GLU B 2 169 ? 239.237 196.027 196.955 1.00 72.55  ? 169  GLU C OE1 1 
ATOM   6112 O OE2 . GLU B 2 169 ? 241.146 195.912 198.034 1.00 72.55  ? 169  GLU C OE2 1 
ATOM   6113 N N   . TYR B 2 170 ? 237.981 195.265 202.340 1.00 71.78  ? 170  TYR C N   1 
ATOM   6114 C CA  . TYR B 2 170 ? 238.266 196.064 203.524 1.00 71.78  ? 170  TYR C CA  1 
ATOM   6115 C C   . TYR B 2 170 ? 239.696 195.803 203.971 1.00 71.78  ? 170  TYR C C   1 
ATOM   6116 O O   . TYR B 2 170 ? 240.099 194.646 204.122 1.00 71.78  ? 170  TYR C O   1 
ATOM   6117 C CB  . TYR B 2 170 ? 237.286 195.743 204.658 1.00 71.78  ? 170  TYR C CB  1 
ATOM   6118 C CG  . TYR B 2 170 ? 237.614 196.425 205.967 1.00 71.78  ? 170  TYR C CG  1 
ATOM   6119 C CD1 . TYR B 2 170 ? 238.289 195.749 206.975 1.00 71.78  ? 170  TYR C CD1 1 
ATOM   6120 C CD2 . TYR B 2 170 ? 237.249 197.745 206.195 1.00 71.78  ? 170  TYR C CD2 1 
ATOM   6121 C CE1 . TYR B 2 170 ? 238.591 196.368 208.173 1.00 71.78  ? 170  TYR C CE1 1 
ATOM   6122 C CE2 . TYR B 2 170 ? 237.547 198.373 207.390 1.00 71.78  ? 170  TYR C CE2 1 
ATOM   6123 C CZ  . TYR B 2 170 ? 238.218 197.679 208.375 1.00 71.78  ? 170  TYR C CZ  1 
ATOM   6124 O OH  . TYR B 2 170 ? 238.517 198.299 209.566 1.00 71.78  ? 170  TYR C OH  1 
ATOM   6125 N N   . VAL B 2 171 ? 240.453 196.878 204.179 1.00 72.43  ? 171  VAL C N   1 
ATOM   6126 C CA  . VAL B 2 171 ? 241.823 196.797 204.668 1.00 72.43  ? 171  VAL C CA  1 
ATOM   6127 C C   . VAL B 2 171 ? 241.983 197.768 205.829 1.00 72.43  ? 171  VAL C C   1 
ATOM   6128 O O   . VAL B 2 171 ? 241.348 198.827 205.872 1.00 72.43  ? 171  VAL C O   1 
ATOM   6129 C CB  . VAL B 2 171 ? 242.857 197.097 203.559 1.00 72.43  ? 171  VAL C CB  1 
ATOM   6130 C CG1 . VAL B 2 171 ? 242.856 195.988 202.519 1.00 72.43  ? 171  VAL C CG1 1 
ATOM   6131 C CG2 . VAL B 2 171 ? 242.568 198.441 202.910 1.00 72.43  ? 171  VAL C CG2 1 
ATOM   6132 N N   . SER B 2 172 ? 242.835 197.396 206.779 1.00 75.09  ? 172  SER C N   1 
ATOM   6133 C CA  . SER B 2 172 ? 243.071 198.193 207.970 1.00 75.09  ? 172  SER C CA  1 
ATOM   6134 C C   . SER B 2 172 ? 244.319 199.054 207.791 1.00 75.09  ? 172  SER C C   1 
ATOM   6135 O O   . SER B 2 172 ? 244.988 199.025 206.755 1.00 75.09  ? 172  SER C O   1 
ATOM   6136 C CB  . SER B 2 172 ? 243.194 197.291 209.200 1.00 75.09  ? 172  SER C CB  1 
ATOM   6137 O OG  . SER B 2 172 ? 244.275 196.386 209.062 1.00 75.09  ? 172  SER C OG  1 
ATOM   6138 N N   . GLN B 2 173 ? 244.631 199.835 208.822 1.00 79.69  ? 173  GLN C N   1 
ATOM   6139 C CA  . GLN B 2 173 ? 245.807 200.685 208.782 1.00 79.69  ? 173  GLN C CA  1 
ATOM   6140 C C   . GLN B 2 173 ? 247.076 199.836 208.823 1.00 79.69  ? 173  GLN C C   1 
ATOM   6141 O O   . GLN B 2 173 ? 247.090 198.755 209.418 1.00 79.69  ? 173  GLN C O   1 
ATOM   6142 C CB  . GLN B 2 173 ? 245.798 201.666 209.951 1.00 79.69  ? 173  GLN C CB  1 
ATOM   6143 C CG  . GLN B 2 173 ? 244.585 202.583 209.984 1.00 79.69  ? 173  GLN C CG  1 
ATOM   6144 C CD  . GLN B 2 173 ? 244.544 203.545 208.812 1.00 79.69  ? 173  GLN C CD  1 
ATOM   6145 O OE1 . GLN B 2 173 ? 243.471 203.925 208.344 1.00 79.69  ? 173  GLN C OE1 1 
ATOM   6146 N NE2 . GLN B 2 173 ? 245.716 203.951 208.336 1.00 79.69  ? 173  GLN C NE2 1 
ATOM   6147 N N   . PRO B 2 174 ? 248.153 200.299 208.189 1.00 80.34  ? 174  PRO C N   1 
ATOM   6148 C CA  . PRO B 2 174 ? 249.393 199.514 208.180 1.00 80.34  ? 174  PRO C CA  1 
ATOM   6149 C C   . PRO B 2 174 ? 249.975 199.369 209.579 1.00 80.34  ? 174  PRO C C   1 
ATOM   6150 O O   . PRO B 2 174 ? 249.962 200.306 210.380 1.00 80.34  ? 174  PRO C O   1 
ATOM   6151 C CB  . PRO B 2 174 ? 250.320 200.324 207.267 1.00 80.34  ? 174  PRO C CB  1 
ATOM   6152 C CG  . PRO B 2 174 ? 249.404 201.166 206.438 1.00 80.34  ? 174  PRO C CG  1 
ATOM   6153 C CD  . PRO B 2 174 ? 248.249 201.492 207.333 1.00 80.34  ? 174  PRO C CD  1 
ATOM   6154 N N   . PHE B 2 175 ? 250.487 198.175 209.865 1.00 81.09  ? 175  PHE C N   1 
ATOM   6155 C CA  . PHE B 2 175 ? 251.136 197.890 211.136 1.00 81.09  ? 175  PHE C CA  1 
ATOM   6156 C C   . PHE B 2 175 ? 252.188 196.813 210.907 1.00 81.09  ? 175  PHE C C   1 
ATOM   6157 O O   . PHE B 2 175 ? 252.443 196.395 209.774 1.00 81.09  ? 175  PHE C O   1 
ATOM   6158 C CB  . PHE B 2 175 ? 250.115 197.471 212.201 1.00 81.09  ? 175  PHE C CB  1 
ATOM   6159 C CG  . PHE B 2 175 ? 249.344 196.228 211.853 1.00 81.09  ? 175  PHE C CG  1 
ATOM   6160 C CD1 . PHE B 2 175 ? 249.787 194.982 212.268 1.00 81.09  ? 175  PHE C CD1 1 
ATOM   6161 C CD2 . PHE B 2 175 ? 248.172 196.305 211.121 1.00 81.09  ? 175  PHE C CD2 1 
ATOM   6162 C CE1 . PHE B 2 175 ? 249.079 193.838 211.952 1.00 81.09  ? 175  PHE C CE1 1 
ATOM   6163 C CE2 . PHE B 2 175 ? 247.460 195.164 210.801 1.00 81.09  ? 175  PHE C CE2 1 
ATOM   6164 C CZ  . PHE B 2 175 ? 247.914 193.930 211.218 1.00 81.09  ? 175  PHE C CZ  1 
ATOM   6165 N N   . LEU B 2 176 ? 252.805 196.363 212.000 1.00 83.99  ? 176  LEU C N   1 
ATOM   6166 C CA  . LEU B 2 176 ? 253.833 195.326 211.924 1.00 83.99  ? 176  LEU C CA  1 
ATOM   6167 C C   . LEU B 2 176 ? 253.781 194.530 213.224 1.00 83.99  ? 176  LEU C C   1 
ATOM   6168 O O   . LEU B 2 176 ? 254.335 194.960 214.240 1.00 83.99  ? 176  LEU C O   1 
ATOM   6169 C CB  . LEU B 2 176 ? 255.211 195.932 211.692 1.00 83.99  ? 176  LEU C CB  1 
ATOM   6170 C CG  . LEU B 2 176 ? 256.372 194.944 211.572 1.00 83.99  ? 176  LEU C CG  1 
ATOM   6171 C CD1 . LEU B 2 176 ? 256.147 193.991 210.407 1.00 83.99  ? 176  LEU C CD1 1 
ATOM   6172 C CD2 . LEU B 2 176 ? 257.692 195.682 211.418 1.00 83.99  ? 176  LEU C CD2 1 
ATOM   6173 N N   . MET B 2 177 ? 253.117 193.379 213.184 1.00 87.90  ? 177  MET C N   1 
ATOM   6174 C CA  . MET B 2 177 ? 253.001 192.540 214.364 1.00 87.90  ? 177  MET C CA  1 
ATOM   6175 C C   . MET B 2 177 ? 254.264 191.704 214.552 1.00 87.90  ? 177  MET C C   1 
ATOM   6176 O O   . MET B 2 177 ? 255.109 191.586 213.661 1.00 87.90  ? 177  MET C O   1 
ATOM   6177 C CB  . MET B 2 177 ? 251.771 191.638 214.264 1.00 87.90  ? 177  MET C CB  1 
ATOM   6178 C CG  . MET B 2 177 ? 251.814 190.645 213.115 1.00 87.90  ? 177  MET C CG  1 
ATOM   6179 S SD  . MET B 2 177 ? 250.369 189.567 213.090 1.00 87.90  ? 177  MET C SD  1 
ATOM   6180 C CE  . MET B 2 177 ? 250.749 188.516 211.691 1.00 87.90  ? 177  MET C CE  1 
ATOM   6181 N N   . ASP B 2 178 ? 254.386 191.116 215.740 1.00 92.70  ? 178  ASP C N   1 
ATOM   6182 C CA  . ASP B 2 178 ? 255.548 190.298 216.064 1.00 92.70  ? 178  ASP C CA  1 
ATOM   6183 C C   . ASP B 2 178 ? 255.503 188.992 215.279 1.00 92.70  ? 178  ASP C C   1 
ATOM   6184 O O   . ASP B 2 178 ? 254.580 188.188 215.447 1.00 92.70  ? 178  ASP C O   1 
ATOM   6185 C CB  . ASP B 2 178 ? 255.598 190.027 217.566 1.00 92.70  ? 178  ASP C CB  1 
ATOM   6186 C CG  . ASP B 2 178 ? 254.248 189.635 218.134 1.00 92.70  ? 178  ASP C CG  1 
ATOM   6187 O OD1 . ASP B 2 178 ? 253.239 189.742 217.405 1.00 92.70  ? 178  ASP C OD1 1 
ATOM   6188 O OD2 . ASP B 2 178 ? 254.195 189.221 219.311 1.00 92.70  ? 178  ASP C OD2 1 
ATOM   6189 N N   . LEU B 2 179 ? 256.498 188.785 214.419 1.00 90.86  ? 179  LEU C N   1 
ATOM   6190 C CA  . LEU B 2 179 ? 256.580 187.590 213.591 1.00 90.86  ? 179  LEU C CA  1 
ATOM   6191 C C   . LEU B 2 179 ? 257.639 186.606 214.066 1.00 90.86  ? 179  LEU C C   1 
ATOM   6192 O O   . LEU B 2 179 ? 257.821 185.562 213.431 1.00 90.86  ? 179  LEU C O   1 
ATOM   6193 C CB  . LEU B 2 179 ? 256.855 187.976 212.134 1.00 90.86  ? 179  LEU C CB  1 
ATOM   6194 C CG  . LEU B 2 179 ? 255.803 188.855 211.457 1.00 90.86  ? 179  LEU C CG  1 
ATOM   6195 C CD1 . LEU B 2 179 ? 256.242 189.229 210.052 1.00 90.86  ? 179  LEU C CD1 1 
ATOM   6196 C CD2 . LEU B 2 179 ? 254.457 188.150 211.431 1.00 90.86  ? 179  LEU C CD2 1 
ATOM   6197 N N   . GLU B 2 180 ? 258.340 186.904 215.155 1.00 94.65  ? 180  GLU C N   1 
ATOM   6198 C CA  . GLU B 2 180 ? 259.382 186.016 215.643 1.00 94.65  ? 180  GLU C CA  1 
ATOM   6199 C C   . GLU B 2 180 ? 258.774 184.796 216.324 1.00 94.65  ? 180  GLU C C   1 
ATOM   6200 O O   . GLU B 2 180 ? 257.656 184.838 216.844 1.00 94.65  ? 180  GLU C O   1 
ATOM   6201 C CB  . GLU B 2 180 ? 260.311 186.749 216.615 1.00 94.65  ? 180  GLU C CB  1 
ATOM   6202 C CG  . GLU B 2 180 ? 259.707 187.041 217.982 1.00 94.65  ? 180  GLU C CG  1 
ATOM   6203 C CD  . GLU B 2 180 ? 258.714 188.187 217.960 1.00 94.65  ? 180  GLU C CD  1 
ATOM   6204 O OE1 . GLU B 2 180 ? 258.634 188.891 216.931 1.00 94.65  ? 180  GLU C OE1 1 
ATOM   6205 O OE2 . GLU B 2 180 ? 258.015 188.385 218.975 1.00 94.65  ? 180  GLU C OE2 1 
ATOM   6206 N N   . GLY B 2 181 ? 259.526 183.699 216.310 1.00 90.22  ? 181  GLY C N   1 
ATOM   6207 C CA  . GLY B 2 181 ? 259.073 182.468 216.924 1.00 90.22  ? 181  GLY C CA  1 
ATOM   6208 C C   . GLY B 2 181 ? 259.411 182.383 218.397 1.00 90.22  ? 181  GLY C C   1 
ATOM   6209 O O   . GLY B 2 181 ? 260.555 182.098 218.764 1.00 90.22  ? 181  GLY C O   1 
ATOM   6210 N N   . LYS B 2 182 ? 258.423 182.631 219.252 1.00 88.67  ? 182  LYS C N   1 
ATOM   6211 C CA  . LYS B 2 182 ? 258.643 182.562 220.688 1.00 88.67  ? 182  LYS C CA  1 
ATOM   6212 C C   . LYS B 2 182 ? 258.778 181.112 221.140 1.00 88.67  ? 182  LYS C C   1 
ATOM   6213 O O   . LYS B 2 182 ? 258.194 180.196 220.556 1.00 88.67  ? 182  LYS C O   1 
ATOM   6214 C CB  . LYS B 2 182 ? 257.497 183.241 221.437 1.00 88.67  ? 182  LYS C CB  1 
ATOM   6215 C CG  . LYS B 2 182 ? 257.301 184.705 221.075 1.00 88.67  ? 182  LYS C CG  1 
ATOM   6216 C CD  . LYS B 2 182 ? 258.539 185.542 221.377 1.00 88.67  ? 182  LYS C CD  1 
ATOM   6217 C CE  . LYS B 2 182 ? 258.642 185.909 222.854 1.00 88.67  ? 182  LYS C CE  1 
ATOM   6218 N NZ  . LYS B 2 182 ? 259.096 184.782 223.717 1.00 88.67  ? 182  LYS C NZ  1 
ATOM   6219 N N   . GLN B 2 183 ? 259.563 180.911 222.195 1.00 91.80  ? 183  GLN C N   1 
ATOM   6220 C CA  . GLN B 2 183 ? 259.803 179.592 222.763 1.00 91.80  ? 183  GLN C CA  1 
ATOM   6221 C C   . GLN B 2 183 ? 259.231 179.541 224.171 1.00 91.80  ? 183  GLN C C   1 
ATOM   6222 O O   . GLN B 2 183 ? 259.514 180.419 224.992 1.00 91.80  ? 183  GLN C O   1 
ATOM   6223 C CB  . GLN B 2 183 ? 261.299 179.265 222.784 1.00 91.80  ? 183  GLN C CB  1 
ATOM   6224 C CG  . GLN B 2 183 ? 261.630 177.896 223.359 1.00 91.80  ? 183  GLN C CG  1 
ATOM   6225 C CD  . GLN B 2 183 ? 261.141 176.757 222.484 1.00 91.80  ? 183  GLN C CD  1 
ATOM   6226 O OE1 . GLN B 2 183 ? 260.825 175.674 222.976 1.00 91.80  ? 183  GLN C OE1 1 
ATOM   6227 N NE2 . GLN B 2 183 ? 261.086 176.994 221.178 1.00 91.80  ? 183  GLN C NE2 1 
ATOM   6228 N N   . GLY B 2 184 ? 258.429 178.516 224.444 1.00 83.48  ? 184  GLY C N   1 
ATOM   6229 C CA  . GLY B 2 184 ? 257.831 178.356 225.754 1.00 83.48  ? 184  GLY C CA  1 
ATOM   6230 C C   . GLY B 2 184 ? 256.421 177.804 225.706 1.00 83.48  ? 184  GLY C C   1 
ATOM   6231 O O   . GLY B 2 184 ? 256.174 176.767 225.084 1.00 83.48  ? 184  GLY C O   1 
ATOM   6232 N N   . ASN B 2 185 ? 255.489 178.489 226.359 1.00 79.80  ? 185  ASN C N   1 
ATOM   6233 C CA  . ASN B 2 185 ? 254.095 178.078 226.413 1.00 79.80  ? 185  ASN C CA  1 
ATOM   6234 C C   . ASN B 2 185 ? 253.229 179.044 225.615 1.00 79.80  ? 185  ASN C C   1 
ATOM   6235 O O   . ASN B 2 185 ? 253.683 180.094 225.152 1.00 79.80  ? 185  ASN C O   1 
ATOM   6236 C CB  . ASN B 2 185 ? 253.608 177.999 227.865 1.00 79.80  ? 185  ASN C CB  1 
ATOM   6237 C CG  . ASN B 2 185 ? 254.381 176.986 228.685 1.00 79.80  ? 185  ASN C CG  1 
ATOM   6238 O OD1 . ASN B 2 185 ? 254.876 175.991 228.157 1.00 79.80  ? 185  ASN C OD1 1 
ATOM   6239 N ND2 . ASN B 2 185 ? 254.489 177.235 229.985 1.00 79.80  ? 185  ASN C ND2 1 
ATOM   6240 N N   . PHE B 2 186 ? 251.962 178.670 225.458 1.00 74.32  ? 186  PHE C N   1 
ATOM   6241 C CA  . PHE B 2 186 ? 251.001 179.502 224.741 1.00 74.32  ? 186  PHE C CA  1 
ATOM   6242 C C   . PHE B 2 186 ? 250.610 180.686 225.615 1.00 74.32  ? 186  PHE C C   1 
ATOM   6243 O O   . PHE B 2 186 ? 249.878 180.528 226.598 1.00 74.32  ? 186  PHE C O   1 
ATOM   6244 C CB  . PHE B 2 186 ? 249.777 178.678 224.353 1.00 74.32  ? 186  PHE C CB  1 
ATOM   6245 C CG  . PHE B 2 186 ? 250.074 177.563 223.392 1.00 74.32  ? 186  PHE C CG  1 
ATOM   6246 C CD1 . PHE B 2 186 ? 251.142 177.650 222.516 1.00 74.32  ? 186  PHE C CD1 1 
ATOM   6247 C CD2 . PHE B 2 186 ? 249.285 176.426 223.366 1.00 74.32  ? 186  PHE C CD2 1 
ATOM   6248 C CE1 . PHE B 2 186 ? 251.417 176.625 221.631 1.00 74.32  ? 186  PHE C CE1 1 
ATOM   6249 C CE2 . PHE B 2 186 ? 249.554 175.398 222.483 1.00 74.32  ? 186  PHE C CE2 1 
ATOM   6250 C CZ  . PHE B 2 186 ? 250.622 175.498 221.615 1.00 74.32  ? 186  PHE C CZ  1 
ATOM   6251 N N   . LYS B 2 187 ? 251.096 181.876 225.262 1.00 75.18  ? 187  LYS C N   1 
ATOM   6252 C CA  . LYS B 2 187 ? 250.822 183.094 226.014 1.00 75.18  ? 187  LYS C CA  1 
ATOM   6253 C C   . LYS B 2 187 ? 249.800 183.987 225.319 1.00 75.18  ? 187  LYS C C   1 
ATOM   6254 O O   . LYS B 2 187 ? 249.876 185.216 225.424 1.00 75.18  ? 187  LYS C O   1 
ATOM   6255 C CB  . LYS B 2 187 ? 252.119 183.864 226.261 1.00 75.18  ? 187  LYS C CB  1 
ATOM   6256 C CG  . LYS B 2 187 ? 253.161 183.087 227.046 1.00 75.18  ? 187  LYS C CG  1 
ATOM   6257 C CD  . LYS B 2 187 ? 254.427 183.905 227.243 1.00 75.18  ? 187  LYS C CD  1 
ATOM   6258 C CE  . LYS B 2 187 ? 255.047 184.291 225.910 1.00 75.18  ? 187  LYS C CE  1 
ATOM   6259 N NZ  . LYS B 2 187 ? 256.288 185.094 226.087 1.00 75.18  ? 187  LYS C NZ  1 
ATOM   6260 N N   . ASN B 2 188 ? 248.841 183.392 224.612 1.00 70.90  ? 188  ASN C N   1 
ATOM   6261 C CA  . ASN B 2 188 ? 247.835 184.160 223.894 1.00 70.90  ? 188  ASN C CA  1 
ATOM   6262 C C   . ASN B 2 188 ? 246.649 183.255 223.599 1.00 70.90  ? 188  ASN C C   1 
ATOM   6263 O O   . ASN B 2 188 ? 246.827 182.090 223.235 1.00 70.90  ? 188  ASN C O   1 
ATOM   6264 C CB  . ASN B 2 188 ? 248.404 184.743 222.595 1.00 70.90  ? 188  ASN C CB  1 
ATOM   6265 C CG  . ASN B 2 188 ? 247.552 185.863 222.031 1.00 70.90  ? 188  ASN C CG  1 
ATOM   6266 O OD1 . ASN B 2 188 ? 246.325 185.842 222.134 1.00 70.90  ? 188  ASN C OD1 1 
ATOM   6267 N ND2 . ASN B 2 188 ? 248.202 186.855 221.433 1.00 70.90  ? 188  ASN C ND2 1 
ATOM   6268 N N   . LEU B 2 189 ? 245.443 183.799 223.758 1.00 67.33  ? 189  LEU C N   1 
ATOM   6269 C CA  . LEU B 2 189 ? 244.213 183.060 223.498 1.00 67.33  ? 189  LEU C CA  1 
ATOM   6270 C C   . LEU B 2 189 ? 243.252 183.964 222.743 1.00 67.33  ? 189  LEU C C   1 
ATOM   6271 O O   . LEU B 2 189 ? 242.834 185.001 223.266 1.00 67.33  ? 189  LEU C O   1 
ATOM   6272 C CB  . LEU B 2 189 ? 243.574 182.565 224.799 1.00 67.33  ? 189  LEU C CB  1 
ATOM   6273 C CG  . LEU B 2 189 ? 242.245 181.819 224.663 1.00 67.33  ? 189  LEU C CG  1 
ATOM   6274 C CD1 . LEU B 2 189 ? 242.413 180.563 223.824 1.00 67.33  ? 189  LEU C CD1 1 
ATOM   6275 C CD2 . LEU B 2 189 ? 241.676 181.480 226.032 1.00 67.33  ? 189  LEU C CD2 1 
ATOM   6276 N N   . ARG B 2 190 ? 242.906 183.571 221.520 1.00 66.42  ? 190  ARG C N   1 
ATOM   6277 C CA  . ARG B 2 190 ? 241.978 184.316 220.678 1.00 66.42  ? 190  ARG C CA  1 
ATOM   6278 C C   . ARG B 2 190 ? 240.773 183.437 220.379 1.00 66.42  ? 190  ARG C C   1 
ATOM   6279 O O   . ARG B 2 190 ? 240.910 182.387 219.743 1.00 66.42  ? 190  ARG C O   1 
ATOM   6280 C CB  . ARG B 2 190 ? 242.649 184.768 219.380 1.00 66.42  ? 190  ARG C CB  1 
ATOM   6281 C CG  . ARG B 2 190 ? 243.752 185.794 219.572 1.00 66.42  ? 190  ARG C CG  1 
ATOM   6282 C CD  . ARG B 2 190 ? 244.347 186.213 218.239 1.00 66.42  ? 190  ARG C CD  1 
ATOM   6283 N NE  . ARG B 2 190 ? 245.338 187.273 218.392 1.00 66.42  ? 190  ARG C NE  1 
ATOM   6284 C CZ  . ARG B 2 190 ? 246.629 187.060 218.623 1.00 66.42  ? 190  ARG C CZ  1 
ATOM   6285 N NH1 . ARG B 2 190 ? 247.460 188.086 218.748 1.00 66.42  ? 190  ARG C NH1 1 
ATOM   6286 N NH2 . ARG B 2 190 ? 247.089 185.821 218.732 1.00 66.42  ? 190  ARG C NH2 1 
ATOM   6287 N N   . GLU B 2 191 ? 239.601 183.866 220.836 1.00 63.09  ? 191  GLU C N   1 
ATOM   6288 C CA  . GLU B 2 191 ? 238.356 183.143 220.622 1.00 63.09  ? 191  GLU C CA  1 
ATOM   6289 C C   . GLU B 2 191 ? 237.508 183.874 219.592 1.00 63.09  ? 191  GLU C C   1 
ATOM   6290 O O   . GLU B 2 191 ? 237.421 185.106 219.606 1.00 63.09  ? 191  GLU C O   1 
ATOM   6291 C CB  . GLU B 2 191 ? 237.578 182.992 221.932 1.00 63.09  ? 191  GLU C CB  1 
ATOM   6292 C CG  . GLU B 2 191 ? 238.345 182.271 223.026 1.00 63.09  ? 191  GLU C CG  1 
ATOM   6293 C CD  . GLU B 2 191 ? 237.570 182.193 224.325 1.00 63.09  ? 191  GLU C CD  1 
ATOM   6294 O OE1 . GLU B 2 191 ? 236.413 182.662 224.358 1.00 63.09  ? 191  GLU C OE1 1 
ATOM   6295 O OE2 . GLU B 2 191 ? 238.118 181.664 225.314 1.00 63.09  ? 191  GLU C OE2 1 
ATOM   6296 N N   . PHE B 2 192 ? 236.883 183.110 218.698 1.00 60.62  ? 192  PHE C N   1 
ATOM   6297 C CA  . PHE B 2 192 ? 236.061 183.673 217.638 1.00 60.62  ? 192  PHE C CA  1 
ATOM   6298 C C   . PHE B 2 192 ? 234.780 182.865 217.494 1.00 60.62  ? 192  PHE C C   1 
ATOM   6299 O O   . PHE B 2 192 ? 234.789 181.640 217.637 1.00 60.62  ? 192  PHE C O   1 
ATOM   6300 C CB  . PHE B 2 192 ? 236.810 183.700 216.299 1.00 60.62  ? 192  PHE C CB  1 
ATOM   6301 C CG  . PHE B 2 192 ? 237.973 184.649 216.273 1.00 60.62  ? 192  PHE C CG  1 
ATOM   6302 C CD1 . PHE B 2 192 ? 239.246 184.215 216.601 1.00 60.62  ? 192  PHE C CD1 1 
ATOM   6303 C CD2 . PHE B 2 192 ? 237.793 185.976 215.920 1.00 60.62  ? 192  PHE C CD2 1 
ATOM   6304 C CE1 . PHE B 2 192 ? 240.318 185.086 216.577 1.00 60.62  ? 192  PHE C CE1 1 
ATOM   6305 C CE2 . PHE B 2 192 ? 238.861 186.852 215.895 1.00 60.62  ? 192  PHE C CE2 1 
ATOM   6306 C CZ  . PHE B 2 192 ? 240.125 186.406 216.224 1.00 60.62  ? 192  PHE C CZ  1 
ATOM   6307 N N   . VAL B 2 193 ? 233.682 183.563 217.210 1.00 59.01  ? 193  VAL C N   1 
ATOM   6308 C CA  . VAL B 2 193 ? 232.385 182.947 216.955 1.00 59.01  ? 193  VAL C CA  1 
ATOM   6309 C C   . VAL B 2 193 ? 231.817 183.573 215.690 1.00 59.01  ? 193  VAL C C   1 
ATOM   6310 O O   . VAL B 2 193 ? 231.561 184.783 215.654 1.00 59.01  ? 193  VAL C O   1 
ATOM   6311 C CB  . VAL B 2 193 ? 231.412 183.128 218.133 1.00 59.01  ? 193  VAL C CB  1 
ATOM   6312 C CG1 . VAL B 2 193 ? 230.016 182.672 217.739 1.00 59.01  ? 193  VAL C CG1 1 
ATOM   6313 C CG2 . VAL B 2 193 ? 231.899 182.357 219.348 1.00 59.01  ? 193  VAL C CG2 1 
ATOM   6314 N N   . PHE B 2 194 ? 231.622 182.758 214.659 1.00 59.46  ? 194  PHE C N   1 
ATOM   6315 C CA  . PHE B 2 194 ? 231.147 183.222 213.363 1.00 59.46  ? 194  PHE C CA  1 
ATOM   6316 C C   . PHE B 2 194 ? 229.699 182.797 213.165 1.00 59.46  ? 194  PHE C C   1 
ATOM   6317 O O   . PHE B 2 194 ? 229.348 181.639 213.411 1.00 59.46  ? 194  PHE C O   1 
ATOM   6318 C CB  . PHE B 2 194 ? 232.019 182.672 212.232 1.00 59.46  ? 194  PHE C CB  1 
ATOM   6319 C CG  . PHE B 2 194 ? 233.479 182.993 212.383 1.00 59.46  ? 194  PHE C CG  1 
ATOM   6320 C CD1 . PHE B 2 194 ? 233.974 184.226 211.994 1.00 59.46  ? 194  PHE C CD1 1 
ATOM   6321 C CD2 . PHE B 2 194 ? 234.355 182.060 212.912 1.00 59.46  ? 194  PHE C CD2 1 
ATOM   6322 C CE1 . PHE B 2 194 ? 235.316 184.523 212.131 1.00 59.46  ? 194  PHE C CE1 1 
ATOM   6323 C CE2 . PHE B 2 194 ? 235.699 182.352 213.051 1.00 59.46  ? 194  PHE C CE2 1 
ATOM   6324 C CZ  . PHE B 2 194 ? 236.179 183.585 212.660 1.00 59.46  ? 194  PHE C CZ  1 
ATOM   6325 N N   . LYS B 2 195 ? 228.865 183.736 212.722 1.00 60.48  ? 195  LYS C N   1 
ATOM   6326 C CA  . LYS B 2 195 ? 227.459 183.474 212.457 1.00 60.48  ? 195  LYS C CA  1 
ATOM   6327 C C   . LYS B 2 195 ? 227.075 184.103 211.127 1.00 60.48  ? 195  LYS C C   1 
ATOM   6328 O O   . LYS B 2 195 ? 227.577 185.171 210.769 1.00 60.48  ? 195  LYS C O   1 
ATOM   6329 C CB  . LYS B 2 195 ? 226.561 184.024 213.573 1.00 60.48  ? 195  LYS C CB  1 
ATOM   6330 C CG  . LYS B 2 195 ? 226.758 183.354 214.922 1.00 60.48  ? 195  LYS C CG  1 
ATOM   6331 C CD  . LYS B 2 195 ? 225.877 183.990 215.984 1.00 60.48  ? 195  LYS C CD  1 
ATOM   6332 C CE  . LYS B 2 195 ? 224.409 183.910 215.604 1.00 60.48  ? 195  LYS C CE  1 
ATOM   6333 N NZ  . LYS B 2 195 ? 223.537 184.544 216.630 1.00 60.48  ? 195  LYS C NZ  1 
ATOM   6334 N N   . ASN B 2 196 ? 226.180 183.434 210.400 1.00 63.39  ? 196  ASN C N   1 
ATOM   6335 C CA  . ASN B 2 196 ? 225.698 183.898 209.098 1.00 63.39  ? 196  ASN C CA  1 
ATOM   6336 C C   . ASN B 2 196 ? 224.177 183.776 209.098 1.00 63.39  ? 196  ASN C C   1 
ATOM   6337 O O   . ASN B 2 196 ? 223.630 182.721 208.769 1.00 63.39  ? 196  ASN C O   1 
ATOM   6338 C CB  . ASN B 2 196 ? 226.332 183.101 207.962 1.00 63.39  ? 196  ASN C CB  1 
ATOM   6339 C CG  . ASN B 2 196 ? 225.895 183.588 206.595 1.00 63.39  ? 196  ASN C CG  1 
ATOM   6340 O OD1 . ASN B 2 196 ? 225.495 184.740 206.431 1.00 63.39  ? 196  ASN C OD1 1 
ATOM   6341 N ND2 . ASN B 2 196 ? 225.969 182.709 205.603 1.00 63.39  ? 196  ASN C ND2 1 
ATOM   6342 N N   . ILE B 2 197 ? 223.497 184.859 209.469 1.00 64.73  ? 197  ILE C N   1 
ATOM   6343 C CA  . ILE B 2 197 ? 222.042 184.895 209.530 1.00 64.73  ? 197  ILE C CA  1 
ATOM   6344 C C   . ILE B 2 197 ? 221.553 186.159 208.839 1.00 64.73  ? 197  ILE C C   1 
ATOM   6345 O O   . ILE B 2 197 ? 222.151 187.231 208.987 1.00 64.73  ? 197  ILE C O   1 
ATOM   6346 C CB  . ILE B 2 197 ? 221.527 184.834 210.985 1.00 64.73  ? 197  ILE C CB  1 
ATOM   6347 C CG1 . ILE B 2 197 ? 222.240 185.873 211.853 1.00 64.73  ? 197  ILE C CG1 1 
ATOM   6348 C CG2 . ILE B 2 197 ? 221.708 183.436 211.557 1.00 64.73  ? 197  ILE C CG2 1 
ATOM   6349 C CD1 . ILE B 2 197 ? 221.793 185.870 213.298 1.00 64.73  ? 197  ILE C CD1 1 
ATOM   6350 N N   . ASP B 2 198 ? 220.466 186.025 208.074 1.00 70.26  ? 198  ASP C N   1 
ATOM   6351 C CA  . ASP B 2 198 ? 219.836 187.145 207.372 1.00 70.26  ? 198  ASP C CA  1 
ATOM   6352 C C   . ASP B 2 198 ? 220.809 187.855 206.435 1.00 70.26  ? 198  ASP C C   1 
ATOM   6353 O O   . ASP B 2 198 ? 220.702 189.063 206.212 1.00 70.26  ? 198  ASP C O   1 
ATOM   6354 C CB  . ASP B 2 198 ? 219.220 188.142 208.358 1.00 70.26  ? 198  ASP C CB  1 
ATOM   6355 C CG  . ASP B 2 198 ? 218.162 187.511 209.240 1.00 70.26  ? 198  ASP C CG  1 
ATOM   6356 O OD1 . ASP B 2 198 ? 217.503 186.552 208.788 1.00 70.26  ? 198  ASP C OD1 1 
ATOM   6357 O OD2 . ASP B 2 198 ? 217.988 187.975 210.387 1.00 70.26  ? 198  ASP C OD2 1 
ATOM   6358 N N   . GLY B 2 199 ? 221.764 187.114 205.879 1.00 64.61  ? 199  GLY C N   1 
ATOM   6359 C CA  . GLY B 2 199 ? 222.735 187.682 204.969 1.00 64.61  ? 199  GLY C CA  1 
ATOM   6360 C C   . GLY B 2 199 ? 223.840 188.484 205.619 1.00 64.61  ? 199  GLY C C   1 
ATOM   6361 O O   . GLY B 2 199 ? 224.688 189.029 204.901 1.00 64.61  ? 199  GLY C O   1 
ATOM   6362 N N   . TYR B 2 200 ? 223.862 188.582 206.944 1.00 62.70  ? 200  TYR C N   1 
ATOM   6363 C CA  . TYR B 2 200 ? 224.900 189.306 207.662 1.00 62.70  ? 200  TYR C CA  1 
ATOM   6364 C C   . TYR B 2 200 ? 225.860 188.316 208.307 1.00 62.70  ? 200  TYR C C   1 
ATOM   6365 O O   . TYR B 2 200 ? 225.427 187.332 208.917 1.00 62.70  ? 200  TYR C O   1 
ATOM   6366 C CB  . TYR B 2 200 ? 224.293 190.224 208.725 1.00 62.70  ? 200  TYR C CB  1 
ATOM   6367 C CG  . TYR B 2 200 ? 223.616 191.453 208.163 1.00 62.70  ? 200  TYR C CG  1 
ATOM   6368 C CD1 . TYR B 2 200 ? 222.298 191.407 207.730 1.00 62.70  ? 200  TYR C CD1 1 
ATOM   6369 C CD2 . TYR B 2 200 ? 224.294 192.661 208.071 1.00 62.70  ? 200  TYR C CD2 1 
ATOM   6370 C CE1 . TYR B 2 200 ? 221.676 192.530 207.217 1.00 62.70  ? 200  TYR C CE1 1 
ATOM   6371 C CE2 . TYR B 2 200 ? 223.680 193.789 207.561 1.00 62.70  ? 200  TYR C CE2 1 
ATOM   6372 C CZ  . TYR B 2 200 ? 222.372 193.717 207.136 1.00 62.70  ? 200  TYR C CZ  1 
ATOM   6373 O OH  . TYR B 2 200 ? 221.756 194.837 206.627 1.00 62.70  ? 200  TYR C OH  1 
ATOM   6374 N N   . PHE B 2 201 ? 227.157 188.577 208.169 1.00 59.74  ? 201  PHE C N   1 
ATOM   6375 C CA  . PHE B 2 201 ? 228.200 187.723 208.732 1.00 59.74  ? 201  PHE C CA  1 
ATOM   6376 C C   . PHE B 2 201 ? 228.706 188.383 210.010 1.00 59.74  ? 201  PHE C C   1 
ATOM   6377 O O   . PHE B 2 201 ? 229.497 189.327 209.963 1.00 59.74  ? 201  PHE C O   1 
ATOM   6378 C CB  . PHE B 2 201 ? 229.323 187.504 207.724 1.00 59.74  ? 201  PHE C CB  1 
ATOM   6379 C CG  . PHE B 2 201 ? 230.269 186.400 208.101 1.00 59.74  ? 201  PHE C CG  1 
ATOM   6380 C CD1 . PHE B 2 201 ? 229.977 185.084 207.784 1.00 59.74  ? 201  PHE C CD1 1 
ATOM   6381 C CD2 . PHE B 2 201 ? 231.450 186.678 208.768 1.00 59.74  ? 201  PHE C CD2 1 
ATOM   6382 C CE1 . PHE B 2 201 ? 230.844 184.065 208.128 1.00 59.74  ? 201  PHE C CE1 1 
ATOM   6383 C CE2 . PHE B 2 201 ? 232.321 185.663 209.113 1.00 59.74  ? 201  PHE C CE2 1 
ATOM   6384 C CZ  . PHE B 2 201 ? 232.018 184.355 208.793 1.00 59.74  ? 201  PHE C CZ  1 
ATOM   6385 N N   . LYS B 2 202 ? 228.244 187.883 211.152 1.00 58.27  ? 202  LYS C N   1 
ATOM   6386 C CA  . LYS B 2 202 ? 228.603 188.442 212.448 1.00 58.27  ? 202  LYS C CA  1 
ATOM   6387 C C   . LYS B 2 202 ? 229.842 187.741 212.991 1.00 58.27  ? 202  LYS C C   1 
ATOM   6388 O O   . LYS B 2 202 ? 229.915 186.508 212.995 1.00 58.27  ? 202  LYS C O   1 
ATOM   6389 C CB  . LYS B 2 202 ? 227.441 188.305 213.432 1.00 58.27  ? 202  LYS C CB  1 
ATOM   6390 C CG  . LYS B 2 202 ? 226.149 188.945 212.952 1.00 58.27  ? 202  LYS C CG  1 
ATOM   6391 C CD  . LYS B 2 202 ? 225.028 188.748 213.957 1.00 58.27  ? 202  LYS C CD  1 
ATOM   6392 C CE  . LYS B 2 202 ? 223.729 189.357 213.458 1.00 58.27  ? 202  LYS C CE  1 
ATOM   6393 N NZ  . LYS B 2 202 ? 223.865 190.818 213.204 1.00 58.27  ? 202  LYS C NZ  1 
ATOM   6394 N N   . ILE B 2 203 ? 230.811 188.531 213.448 1.00 58.34  ? 203  ILE C N   1 
ATOM   6395 C CA  . ILE B 2 203 ? 232.066 188.020 213.986 1.00 58.34  ? 203  ILE C CA  1 
ATOM   6396 C C   . ILE B 2 203 ? 232.214 188.514 215.417 1.00 58.34  ? 203  ILE C C   1 
ATOM   6397 O O   . ILE B 2 203 ? 232.117 189.719 215.678 1.00 58.34  ? 203  ILE C O   1 
ATOM   6398 C CB  . ILE B 2 203 ? 233.271 188.455 213.132 1.00 58.34  ? 203  ILE C CB  1 
ATOM   6399 C CG1 . ILE B 2 203 ? 233.118 187.950 211.697 1.00 58.34  ? 203  ILE C CG1 1 
ATOM   6400 C CG2 . ILE B 2 203 ? 234.568 187.949 213.743 1.00 58.34  ? 203  ILE C CG2 1 
ATOM   6401 C CD1 . ILE B 2 203 ? 234.276 188.312 210.796 1.00 58.34  ? 203  ILE C CD1 1 
ATOM   6402 N N   . TYR B 2 204 ? 232.449 187.585 216.338 1.00 59.34  ? 204  TYR C N   1 
ATOM   6403 C CA  . TYR B 2 204 ? 232.696 187.896 217.737 1.00 59.34  ? 204  TYR C CA  1 
ATOM   6404 C C   . TYR B 2 204 ? 234.131 187.532 218.092 1.00 59.34  ? 204  TYR C C   1 
ATOM   6405 O O   . TYR B 2 204 ? 234.689 186.563 217.569 1.00 59.34  ? 204  TYR C O   1 
ATOM   6406 C CB  . TYR B 2 204 ? 231.720 187.145 218.650 1.00 59.34  ? 204  TYR C CB  1 
ATOM   6407 C CG  . TYR B 2 204 ? 230.265 187.457 218.378 1.00 59.34  ? 204  TYR C CG  1 
ATOM   6408 C CD1 . TYR B 2 204 ? 229.554 186.763 217.408 1.00 59.34  ? 204  TYR C CD1 1 
ATOM   6409 C CD2 . TYR B 2 204 ? 229.602 188.446 219.092 1.00 59.34  ? 204  TYR C CD2 1 
ATOM   6410 C CE1 . TYR B 2 204 ? 228.226 187.046 217.156 1.00 59.34  ? 204  TYR C CE1 1 
ATOM   6411 C CE2 . TYR B 2 204 ? 228.274 188.735 218.847 1.00 59.34  ? 204  TYR C CE2 1 
ATOM   6412 C CZ  . TYR B 2 204 ? 227.591 188.032 217.879 1.00 59.34  ? 204  TYR C CZ  1 
ATOM   6413 O OH  . TYR B 2 204 ? 226.268 188.317 217.632 1.00 59.34  ? 204  TYR C OH  1 
ATOM   6414 N N   . SER B 2 205 ? 234.731 188.320 218.982 1.00 60.69  ? 205  SER C N   1 
ATOM   6415 C CA  . SER B 2 205 ? 236.128 188.135 219.342 1.00 60.69  ? 205  SER C CA  1 
ATOM   6416 C C   . SER B 2 205 ? 236.320 188.405 220.827 1.00 60.69  ? 205  SER C C   1 
ATOM   6417 O O   . SER B 2 205 ? 235.548 189.134 221.455 1.00 60.69  ? 205  SER C O   1 
ATOM   6418 C CB  . SER B 2 205 ? 237.048 189.046 218.518 1.00 60.69  ? 205  SER C CB  1 
ATOM   6419 O OG  . SER B 2 205 ? 236.740 190.411 218.736 1.00 60.69  ? 205  SER C OG  1 
ATOM   6420 N N   . LYS B 2 206 ? 237.373 187.804 221.380 1.00 61.17  ? 206  LYS C N   1 
ATOM   6421 C CA  . LYS B 2 206 ? 237.732 187.996 222.779 1.00 61.17  ? 206  LYS C CA  1 
ATOM   6422 C C   . LYS B 2 206 ? 239.167 187.535 222.977 1.00 61.17  ? 206  LYS C C   1 
ATOM   6423 O O   . LYS B 2 206 ? 239.512 186.407 222.613 1.00 61.17  ? 206  LYS C O   1 
ATOM   6424 C CB  . LYS B 2 206 ? 236.789 187.223 223.708 1.00 61.17  ? 206  LYS C CB  1 
ATOM   6425 C CG  . LYS B 2 206 ? 237.083 187.415 225.186 1.00 61.17  ? 206  LYS C CG  1 
ATOM   6426 C CD  . LYS B 2 206 ? 236.971 188.877 225.583 1.00 61.17  ? 206  LYS C CD  1 
ATOM   6427 C CE  . LYS B 2 206 ? 237.268 189.073 227.059 1.00 61.17  ? 206  LYS C CE  1 
ATOM   6428 N NZ  . LYS B 2 206 ? 237.158 190.502 227.461 1.00 61.17  ? 206  LYS C NZ  1 
ATOM   6429 N N   . HIS B 2 207 ? 239.996 188.405 223.547 1.00 67.06  ? 207  HIS C N   1 
ATOM   6430 C CA  . HIS B 2 207 ? 241.403 188.118 223.793 1.00 67.06  ? 207  HIS C CA  1 
ATOM   6431 C C   . HIS B 2 207 ? 241.627 188.006 225.295 1.00 67.06  ? 207  HIS C C   1 
ATOM   6432 O O   . HIS B 2 207 ? 241.324 188.943 226.043 1.00 67.06  ? 207  HIS C O   1 
ATOM   6433 C CB  . HIS B 2 207 ? 242.295 189.204 223.191 1.00 67.06  ? 207  HIS C CB  1 
ATOM   6434 C CG  . HIS B 2 207 ? 243.759 188.904 223.279 1.00 67.06  ? 207  HIS C CG  1 
ATOM   6435 N ND1 . HIS B 2 207 ? 244.728 189.821 222.932 1.00 67.06  ? 207  HIS C ND1 1 
ATOM   6436 C CD2 . HIS B 2 207 ? 244.421 187.790 223.672 1.00 67.06  ? 207  HIS C CD2 1 
ATOM   6437 C CE1 . HIS B 2 207 ? 245.922 189.286 223.109 1.00 67.06  ? 207  HIS C CE1 1 
ATOM   6438 N NE2 . HIS B 2 207 ? 245.764 188.054 223.558 1.00 67.06  ? 207  HIS C NE2 1 
ATOM   6439 N N   . THR B 2 208 ? 242.155 186.868 225.731 1.00 67.61  ? 208  THR C N   1 
ATOM   6440 C CA  . THR B 2 208 ? 242.413 186.610 227.147 1.00 67.61  ? 208  THR C CA  1 
ATOM   6441 C C   . THR B 2 208 ? 243.833 186.086 227.309 1.00 67.61  ? 208  THR C C   1 
ATOM   6442 O O   . THR B 2 208 ? 244.126 184.956 226.867 1.00 67.61  ? 208  THR C O   1 
ATOM   6443 C CB  . THR B 2 208 ? 241.405 185.615 227.716 1.00 67.61  ? 208  THR C CB  1 
ATOM   6444 O OG1 . THR B 2 208 ? 240.079 186.134 227.560 1.00 67.61  ? 208  THR C OG1 1 
ATOM   6445 C CG2 . THR B 2 208 ? 241.677 185.368 229.192 1.00 67.61  ? 208  THR C CG2 1 
ATOM   6446 N N   . PRO B 2 209 ? 244.739 186.854 227.916 1.00 68.79  ? 209  PRO C N   1 
ATOM   6447 C CA  . PRO B 2 209 ? 246.116 186.373 228.114 1.00 68.79  ? 209  PRO C CA  1 
ATOM   6448 C C   . PRO B 2 209 ? 246.144 185.189 229.070 1.00 68.79  ? 209  PRO C C   1 
ATOM   6449 O O   . PRO B 2 209 ? 245.773 185.310 230.239 1.00 68.79  ? 209  PRO C O   1 
ATOM   6450 C CB  . PRO B 2 209 ? 246.839 187.593 228.701 1.00 68.79  ? 209  PRO C CB  1 
ATOM   6451 C CG  . PRO B 2 209 ? 245.979 188.766 228.340 1.00 68.79  ? 209  PRO C CG  1 
ATOM   6452 C CD  . PRO B 2 209 ? 244.574 188.250 228.352 1.00 68.79  ? 209  PRO C CD  1 
ATOM   6453 N N   . ILE B 2 210 ? 246.588 184.039 228.565 1.00 70.65  ? 210  ILE C N   1 
ATOM   6454 C CA  . ILE B 2 210 ? 246.692 182.831 229.375 1.00 70.65  ? 210  ILE C CA  1 
ATOM   6455 C C   . ILE B 2 210 ? 248.129 182.328 229.344 1.00 70.65  ? 210  ILE C C   1 
ATOM   6456 O O   . ILE B 2 210 ? 248.992 182.920 228.688 1.00 70.65  ? 210  ILE C O   1 
ATOM   6457 C CB  . ILE B 2 210 ? 245.721 181.740 228.887 1.00 70.65  ? 210  ILE C CB  1 
ATOM   6458 C CG1 . ILE B 2 210 ? 246.093 181.290 227.473 1.00 70.65  ? 210  ILE C CG1 1 
ATOM   6459 C CG2 . ILE B 2 210 ? 244.286 182.241 228.935 1.00 70.65  ? 210  ILE C CG2 1 
ATOM   6460 C CD1 . ILE B 2 210 ? 245.268 180.129 226.966 1.00 70.65  ? 210  ILE C CD1 1 
ATOM   6461 N N   . ASN B 2 211 ? 248.394 181.233 230.059 1.00 74.76  ? 211  ASN C N   1 
ATOM   6462 C CA  . ASN B 2 211 ? 249.718 180.607 230.054 1.00 74.76  ? 211  ASN C CA  1 
ATOM   6463 C C   . ASN B 2 211 ? 249.507 179.102 230.235 1.00 74.76  ? 211  ASN C C   1 
ATOM   6464 O O   . ASN B 2 211 ? 249.421 178.607 231.360 1.00 74.76  ? 211  ASN C O   1 
ATOM   6465 C CB  . ASN B 2 211 ? 250.616 181.185 231.137 1.00 74.76  ? 211  ASN C CB  1 
ATOM   6466 C CG  . ASN B 2 211 ? 251.980 180.525 231.177 1.00 74.76  ? 211  ASN C CG  1 
ATOM   6467 O OD1 . ASN B 2 211 ? 252.899 180.931 230.466 1.00 74.76  ? 211  ASN C OD1 1 
ATOM   6468 N ND2 . ASN B 2 211 ? 252.119 179.503 232.013 1.00 74.76  ? 211  ASN C ND2 1 
ATOM   6469 N N   . LEU B 2 212 ? 249.436 178.389 229.114 1.00 76.94  ? 212  LEU C N   1 
ATOM   6470 C CA  . LEU B 2 212 ? 249.190 176.955 229.126 1.00 76.94  ? 212  LEU C CA  1 
ATOM   6471 C C   . LEU B 2 212 ? 249.972 176.315 227.988 1.00 76.94  ? 212  LEU C C   1 
ATOM   6472 O O   . LEU B 2 212 ? 250.480 176.995 227.094 1.00 76.94  ? 212  LEU C O   1 
ATOM   6473 C CB  . LEU B 2 212 ? 247.694 176.641 229.000 1.00 76.94  ? 212  LEU C CB  1 
ATOM   6474 C CG  . LEU B 2 212 ? 247.026 175.821 230.108 1.00 76.94  ? 212  LEU C CG  1 
ATOM   6475 C CD1 . LEU B 2 212 ? 247.772 174.518 230.357 1.00 76.94  ? 212  LEU C CD1 1 
ATOM   6476 C CD2 . LEU B 2 212 ? 246.901 176.628 231.392 1.00 76.94  ? 212  LEU C CD2 1 
ATOM   6477 N N   . VAL B 2 213 ? 250.065 174.987 228.034 1.00 78.17  ? 213  VAL C N   1 
ATOM   6478 C CA  . VAL B 2 213 ? 250.710 174.227 226.979 1.00 78.17  ? 213  VAL C CA  1 
ATOM   6479 C C   . VAL B 2 213 ? 249.706 173.490 226.096 1.00 78.17  ? 213  VAL C C   1 
ATOM   6480 O O   . VAL B 2 213 ? 249.944 173.356 224.890 1.00 78.17  ? 213  VAL C O   1 
ATOM   6481 C CB  . VAL B 2 213 ? 251.746 173.245 227.572 1.00 78.17  ? 213  VAL C CB  1 
ATOM   6482 C CG1 . VAL B 2 213 ? 251.079 172.263 228.527 1.00 78.17  ? 213  VAL C CG1 1 
ATOM   6483 C CG2 . VAL B 2 213 ? 252.497 172.511 226.468 1.00 78.17  ? 213  VAL C CG2 1 
ATOM   6484 N N   . ARG B 2 214 ? 248.584 173.037 226.650 1.00 79.57  ? 214  ARG C N   1 
ATOM   6485 C CA  . ARG B 2 214 ? 247.563 172.313 225.906 1.00 79.57  ? 214  ARG C CA  1 
ATOM   6486 C C   . ARG B 2 214 ? 246.326 172.206 226.784 1.00 79.57  ? 214  ARG C C   1 
ATOM   6487 O O   . ARG B 2 214 ? 246.402 172.364 228.006 1.00 79.57  ? 214  ARG C O   1 
ATOM   6488 C CB  . ARG B 2 214 ? 248.049 170.921 225.486 1.00 79.57  ? 214  ARG C CB  1 
ATOM   6489 C CG  . ARG B 2 214 ? 248.605 170.092 226.633 1.00 79.57  ? 214  ARG C CG  1 
ATOM   6490 C CD  . ARG B 2 214 ? 249.229 168.798 226.135 1.00 79.57  ? 214  ARG C CD  1 
ATOM   6491 N NE  . ARG B 2 214 ? 248.248 167.921 225.504 1.00 79.57  ? 214  ARG C NE  1 
ATOM   6492 C CZ  . ARG B 2 214 ? 247.553 166.991 226.150 1.00 79.57  ? 214  ARG C CZ  1 
ATOM   6493 N NH1 . ARG B 2 214 ? 247.730 166.814 227.452 1.00 79.57  ? 214  ARG C NH1 1 
ATOM   6494 N NH2 . ARG B 2 214 ? 246.681 166.238 225.495 1.00 79.57  ? 214  ARG C NH2 1 
ATOM   6495 N N   . ASP B 2 215 ? 245.185 171.937 226.145 1.00 82.73  ? 215  ASP C N   1 
ATOM   6496 C CA  . ASP B 2 215 ? 243.910 171.741 226.839 1.00 82.73  ? 215  ASP C CA  1 
ATOM   6497 C C   . ASP B 2 215 ? 243.556 172.972 227.681 1.00 82.73  ? 215  ASP C C   1 
ATOM   6498 O O   . ASP B 2 215 ? 243.572 172.948 228.914 1.00 82.73  ? 215  ASP C O   1 
ATOM   6499 C CB  . ASP B 2 215 ? 243.942 170.469 227.695 1.00 82.73  ? 215  ASP C CB  1 
ATOM   6500 C CG  . ASP B 2 215 ? 244.092 169.212 226.862 1.00 82.73  ? 215  ASP C CG  1 
ATOM   6501 O OD1 . ASP B 2 215 ? 244.125 169.324 225.619 1.00 82.73  ? 215  ASP C OD1 1 
ATOM   6502 O OD2 . ASP B 2 215 ? 244.175 168.113 227.450 1.00 82.73  ? 215  ASP C OD2 1 
ATOM   6503 N N   . LEU B 2 216 ? 243.261 174.062 226.960 1.00 78.43  ? 216  LEU C N   1 
ATOM   6504 C CA  . LEU B 2 216 ? 242.985 175.391 227.503 1.00 78.43  ? 216  LEU C CA  1 
ATOM   6505 C C   . LEU B 2 216 ? 242.160 175.335 228.785 1.00 78.43  ? 216  LEU C C   1 
ATOM   6506 O O   . LEU B 2 216 ? 241.201 174.559 228.880 1.00 78.43  ? 216  LEU C O   1 
ATOM   6507 C CB  . LEU B 2 216 ? 242.275 176.253 226.453 1.00 78.43  ? 216  LEU C CB  1 
ATOM   6508 C CG  . LEU B 2 216 ? 241.400 175.568 225.397 1.00 78.43  ? 216  LEU C CG  1 
ATOM   6509 C CD1 . LEU B 2 216 ? 240.099 175.041 225.983 1.00 78.43  ? 216  LEU C CD1 1 
ATOM   6510 C CD2 . LEU B 2 216 ? 241.119 176.522 224.246 1.00 78.43  ? 216  LEU C CD2 1 
ATOM   6511 N N   . PRO B 2 217 ? 242.514 176.130 229.792 1.00 81.69  ? 217  PRO C N   1 
ATOM   6512 C CA  . PRO B 2 217 ? 241.890 175.980 231.110 1.00 81.69  ? 217  PRO C CA  1 
ATOM   6513 C C   . PRO B 2 217 ? 240.429 176.402 231.111 1.00 81.69  ? 217  PRO C C   1 
ATOM   6514 O O   . PRO B 2 217 ? 239.939 177.080 230.205 1.00 81.69  ? 217  PRO C O   1 
ATOM   6515 C CB  . PRO B 2 217 ? 242.730 176.898 232.004 1.00 81.69  ? 217  PRO C CB  1 
ATOM   6516 C CG  . PRO B 2 217 ? 243.260 177.934 231.069 1.00 81.69  ? 217  PRO C CG  1 
ATOM   6517 C CD  . PRO B 2 217 ? 243.502 177.223 229.766 1.00 81.69  ? 217  PRO C CD  1 
ATOM   6518 N N   . GLN B 2 218 ? 239.734 175.981 232.163 1.00 80.36  ? 218  GLN C N   1 
ATOM   6519 C CA  . GLN B 2 218 ? 238.326 176.313 232.320 1.00 80.36  ? 218  GLN C CA  1 
ATOM   6520 C C   . GLN B 2 218 ? 238.166 177.770 232.733 1.00 80.36  ? 218  GLN C C   1 
ATOM   6521 O O   . GLN B 2 218 ? 238.916 178.284 233.567 1.00 80.36  ? 218  GLN C O   1 
ATOM   6522 C CB  . GLN B 2 218 ? 237.680 175.397 233.359 1.00 80.36  ? 218  GLN C CB  1 
ATOM   6523 C CG  . GLN B 2 218 ? 236.199 175.651 233.586 1.00 80.36  ? 218  GLN C CG  1 
ATOM   6524 C CD  . GLN B 2 218 ? 235.602 174.723 234.625 1.00 80.36  ? 218  GLN C CD  1 
ATOM   6525 O OE1 . GLN B 2 218 ? 236.295 173.876 235.188 1.00 80.36  ? 218  GLN C OE1 1 
ATOM   6526 N NE2 . GLN B 2 218 ? 234.309 174.878 234.884 1.00 80.36  ? 218  GLN C NE2 1 
ATOM   6527 N N   . GLY B 2 219 ? 237.181 178.434 232.143 1.00 71.24  ? 219  GLY C N   1 
ATOM   6528 C CA  . GLY B 2 219 ? 236.921 179.823 232.470 1.00 71.24  ? 219  GLY C CA  1 
ATOM   6529 C C   . GLY B 2 219 ? 235.701 180.315 231.728 1.00 71.24  ? 219  GLY C C   1 
ATOM   6530 O O   . GLY B 2 219 ? 235.037 179.565 231.004 1.00 71.24  ? 219  GLY C O   1 
ATOM   6531 N N   . PHE B 2 220 ? 235.411 181.598 231.921 1.00 66.63  ? 220  PHE C N   1 
ATOM   6532 C CA  . PHE B 2 220 ? 234.281 182.250 231.274 1.00 66.63  ? 220  PHE C CA  1 
ATOM   6533 C C   . PHE B 2 220 ? 234.755 183.553 230.651 1.00 66.63  ? 220  PHE C C   1 
ATOM   6534 O O   . PHE B 2 220 ? 235.386 184.374 231.324 1.00 66.63  ? 220  PHE C O   1 
ATOM   6535 C CB  . PHE B 2 220 ? 233.148 182.516 232.271 1.00 66.63  ? 220  PHE C CB  1 
ATOM   6536 C CG  . PHE B 2 220 ? 231.846 182.883 231.622 1.00 66.63  ? 220  PHE C CG  1 
ATOM   6537 C CD1 . PHE B 2 220 ? 231.549 184.203 231.328 1.00 66.63  ? 220  PHE C CD1 1 
ATOM   6538 C CD2 . PHE B 2 220 ? 230.918 181.906 231.304 1.00 66.63  ? 220  PHE C CD2 1 
ATOM   6539 C CE1 . PHE B 2 220 ? 230.352 184.542 230.730 1.00 66.63  ? 220  PHE C CE1 1 
ATOM   6540 C CE2 . PHE B 2 220 ? 229.719 182.239 230.706 1.00 66.63  ? 220  PHE C CE2 1 
ATOM   6541 C CZ  . PHE B 2 220 ? 229.435 183.559 230.419 1.00 66.63  ? 220  PHE C CZ  1 
ATOM   6542 N N   . SER B 2 221 ? 234.450 183.738 229.369 1.00 66.01  ? 221  SER C N   1 
ATOM   6543 C CA  . SER B 2 221 ? 234.836 184.943 228.640 1.00 66.01  ? 221  SER C CA  1 
ATOM   6544 C C   . SER B 2 221 ? 233.727 185.272 227.651 1.00 66.01  ? 221  SER C C   1 
ATOM   6545 O O   . SER B 2 221 ? 233.507 184.525 226.692 1.00 66.01  ? 221  SER C O   1 
ATOM   6546 C CB  . SER B 2 221 ? 236.172 184.754 227.921 1.00 66.01  ? 221  SER C CB  1 
ATOM   6547 O OG  . SER B 2 221 ? 237.207 184.455 228.841 1.00 66.01  ? 221  SER C OG  1 
ATOM   6548 N N   . ALA B 2 222 ? 233.032 186.382 227.883 1.00 62.48  ? 222  ALA C N   1 
ATOM   6549 C CA  . ALA B 2 222 ? 231.954 186.807 227.000 1.00 62.48  ? 222  ALA C CA  1 
ATOM   6550 C C   . ALA B 2 222 ? 232.545 187.470 225.762 1.00 62.48  ? 222  ALA C C   1 
ATOM   6551 O O   . ALA B 2 222 ? 233.196 188.515 225.861 1.00 62.48  ? 222  ALA C O   1 
ATOM   6552 C CB  . ALA B 2 222 ? 231.012 187.761 227.729 1.00 62.48  ? 222  ALA C CB  1 
ATOM   6553 N N   . LEU B 2 223 ? 232.319 186.864 224.599 1.00 60.14  ? 223  LEU C N   1 
ATOM   6554 C CA  . LEU B 2 223 ? 232.850 187.396 223.352 1.00 60.14  ? 223  LEU C CA  1 
ATOM   6555 C C   . LEU B 2 223 ? 232.022 188.591 222.900 1.00 60.14  ? 223  LEU C C   1 
ATOM   6556 O O   . LEU B 2 223 ? 230.792 188.515 222.824 1.00 60.14  ? 223  LEU C O   1 
ATOM   6557 C CB  . LEU B 2 223 ? 232.866 186.317 222.268 1.00 60.14  ? 223  LEU C CB  1 
ATOM   6558 C CG  . LEU B 2 223 ? 233.930 185.221 222.382 1.00 60.14  ? 223  LEU C CG  1 
ATOM   6559 C CD1 . LEU B 2 223 ? 233.518 184.133 223.365 1.00 60.14  ? 223  LEU C CD1 1 
ATOM   6560 C CD2 . LEU B 2 223 ? 234.238 184.627 221.017 1.00 60.14  ? 223  LEU C CD2 1 
ATOM   6561 N N   . GLU B 2 224 ? 232.702 189.694 222.598 1.00 60.12  ? 224  GLU C N   1 
ATOM   6562 C CA  . GLU B 2 224 ? 232.078 190.944 222.196 1.00 60.12  ? 224  GLU C CA  1 
ATOM   6563 C C   . GLU B 2 224 ? 231.960 191.025 220.677 1.00 60.12  ? 224  GLU C C   1 
ATOM   6564 O O   . GLU B 2 224 ? 232.815 190.507 219.952 1.00 60.12  ? 224  GLU C O   1 
ATOM   6565 C CB  . GLU B 2 224 ? 232.891 192.130 222.707 1.00 60.12  ? 224  GLU C CB  1 
ATOM   6566 C CG  . GLU B 2 224 ? 233.130 192.114 224.207 1.00 60.12  ? 224  GLU C CG  1 
ATOM   6567 C CD  . GLU B 2 224 ? 234.053 193.227 224.660 1.00 60.12  ? 224  GLU C CD  1 
ATOM   6568 O OE1 . GLU B 2 224 ? 234.545 193.982 223.796 1.00 60.12  ? 224  GLU C OE1 1 
ATOM   6569 O OE2 . GLU B 2 224 ? 234.288 193.346 225.881 1.00 60.12  ? 224  GLU C OE2 1 
ATOM   6570 N N   . PRO B 2 225 ? 230.903 191.662 220.176 1.00 57.85  ? 225  PRO C N   1 
ATOM   6571 C CA  . PRO B 2 225 ? 230.764 191.829 218.724 1.00 57.85  ? 225  PRO C CA  1 
ATOM   6572 C C   . PRO B 2 225 ? 231.874 192.706 218.166 1.00 57.85  ? 225  PRO C C   1 
ATOM   6573 O O   . PRO B 2 225 ? 232.125 193.809 218.657 1.00 57.85  ? 225  PRO C O   1 
ATOM   6574 C CB  . PRO B 2 225 ? 229.388 192.489 218.572 1.00 57.85  ? 225  PRO C CB  1 
ATOM   6575 C CG  . PRO B 2 225 ? 228.665 192.172 219.842 1.00 57.85  ? 225  PRO C CG  1 
ATOM   6576 C CD  . PRO B 2 225 ? 229.718 192.144 220.904 1.00 57.85  ? 225  PRO C CD  1 
ATOM   6577 N N   . LEU B 2 226 ? 232.543 192.204 217.128 1.00 57.64  ? 226  LEU C N   1 
ATOM   6578 C CA  . LEU B 2 226 ? 233.648 192.918 216.499 1.00 57.64  ? 226  LEU C CA  1 
ATOM   6579 C C   . LEU B 2 226 ? 233.208 193.646 215.233 1.00 57.64  ? 226  LEU C C   1 
ATOM   6580 O O   . LEU B 2 226 ? 233.348 194.868 215.135 1.00 57.64  ? 226  LEU C O   1 
ATOM   6581 C CB  . LEU B 2 226 ? 234.791 191.943 216.188 1.00 57.64  ? 226  LEU C CB  1 
ATOM   6582 C CG  . LEU B 2 226 ? 236.035 192.540 215.528 1.00 57.64  ? 226  LEU C CG  1 
ATOM   6583 C CD1 . LEU B 2 226 ? 236.653 193.608 216.415 1.00 57.64  ? 226  LEU C CD1 1 
ATOM   6584 C CD2 . LEU B 2 226 ? 237.047 191.451 215.211 1.00 57.64  ? 226  LEU C CD2 1 
ATOM   6585 N N   . VAL B 2 227 ? 232.669 192.911 214.258 1.00 57.19  ? 227  VAL C N   1 
ATOM   6586 C CA  . VAL B 2 227 ? 232.226 193.484 212.994 1.00 57.19  ? 227  VAL C CA  1 
ATOM   6587 C C   . VAL B 2 227 ? 230.933 192.805 212.564 1.00 57.19  ? 227  VAL C C   1 
ATOM   6588 O O   . VAL B 2 227 ? 230.582 191.723 213.038 1.00 57.19  ? 227  VAL C O   1 
ATOM   6589 C CB  . VAL B 2 227 ? 233.286 193.350 211.876 1.00 57.19  ? 227  VAL C CB  1 
ATOM   6590 C CG1 . VAL B 2 227 ? 234.484 194.246 212.154 1.00 57.19  ? 227  VAL C CG1 1 
ATOM   6591 C CG2 . VAL B 2 227 ? 233.719 191.901 211.728 1.00 57.19  ? 227  VAL C CG2 1 
ATOM   6592 N N   . ASP B 2 228 ? 230.223 193.464 211.651 1.00 60.19  ? 228  ASP C N   1 
ATOM   6593 C CA  . ASP B 2 228 ? 229.001 192.924 211.056 1.00 60.19  ? 228  ASP C CA  1 
ATOM   6594 C C   . ASP B 2 228 ? 229.090 193.189 209.556 1.00 60.19  ? 228  ASP C C   1 
ATOM   6595 O O   . ASP B 2 228 ? 228.767 194.288 209.095 1.00 60.19  ? 228  ASP C O   1 
ATOM   6596 C CB  . ASP B 2 228 ? 227.756 193.556 211.667 1.00 60.19  ? 228  ASP C CB  1 
ATOM   6597 C CG  . ASP B 2 228 ? 226.500 192.748 211.404 1.00 60.19  ? 228  ASP C CG  1 
ATOM   6598 O OD1 . ASP B 2 228 ? 226.458 192.017 210.393 1.00 60.19  ? 228  ASP C OD1 1 
ATOM   6599 O OD2 . ASP B 2 228 ? 225.553 192.843 212.212 1.00 60.19  ? 228  ASP C OD2 1 
ATOM   6600 N N   . LEU B 2 229 ? 229.533 192.182 208.802 1.00 61.26  ? 229  LEU C N   1 
ATOM   6601 C CA  . LEU B 2 229 ? 229.793 192.345 207.379 1.00 61.26  ? 229  LEU C CA  1 
ATOM   6602 C C   . LEU B 2 229 ? 228.561 191.941 206.581 1.00 61.26  ? 229  LEU C C   1 
ATOM   6603 O O   . LEU B 2 229 ? 228.198 190.755 206.584 1.00 61.26  ? 229  LEU C O   1 
ATOM   6604 C CB  . LEU B 2 229 ? 230.992 191.508 206.959 1.00 61.26  ? 229  LEU C CB  1 
ATOM   6605 C CG  . LEU B 2 229 ? 232.281 191.740 207.749 1.00 61.26  ? 229  LEU C CG  1 
ATOM   6606 C CD1 . LEU B 2 229 ? 233.370 190.787 207.286 1.00 61.26  ? 229  LEU C CD1 1 
ATOM   6607 C CD2 . LEU B 2 229 ? 232.738 193.184 207.620 1.00 61.26  ? 229  LEU C CD2 1 
ATOM   6608 N N   . PRO B 2 230 ? 227.890 192.869 205.894 1.00 62.56  ? 230  PRO C N   1 
ATOM   6609 C CA  . PRO B 2 230 ? 226.738 192.503 205.059 1.00 62.56  ? 230  PRO C CA  1 
ATOM   6610 C C   . PRO B 2 230 ? 227.198 191.881 203.749 1.00 62.56  ? 230  PRO C C   1 
ATOM   6611 O O   . PRO B 2 230 ? 227.680 192.575 202.849 1.00 62.56  ? 230  PRO C O   1 
ATOM   6612 C CB  . PRO B 2 230 ? 226.029 193.849 204.836 1.00 62.56  ? 230  PRO C CB  1 
ATOM   6613 C CG  . PRO B 2 230 ? 226.685 194.825 205.782 1.00 62.56  ? 230  PRO C CG  1 
ATOM   6614 C CD  . PRO B 2 230 ? 228.074 194.325 205.962 1.00 62.56  ? 230  PRO C CD  1 
ATOM   6615 N N   . ILE B 2 231 ? 227.045 190.563 203.638 1.00 64.77  ? 231  ILE C N   1 
ATOM   6616 C CA  . ILE B 2 231 ? 227.429 189.823 202.440 1.00 64.77  ? 231  ILE C CA  1 
ATOM   6617 C C   . ILE B 2 231 ? 226.432 188.687 202.251 1.00 64.77  ? 231  ILE C C   1 
ATOM   6618 O O   . ILE B 2 231 ? 226.379 187.760 203.068 1.00 64.77  ? 231  ILE C O   1 
ATOM   6619 C CB  . ILE B 2 231 ? 228.863 189.279 202.517 1.00 64.77  ? 231  ILE C CB  1 
ATOM   6620 C CG1 . ILE B 2 231 ? 229.192 188.824 203.942 1.00 64.77  ? 231  ILE C CG1 1 
ATOM   6621 C CG2 . ILE B 2 231 ? 229.855 190.327 202.044 1.00 64.77  ? 231  ILE C CG2 1 
ATOM   6622 C CD1 . ILE B 2 231 ? 230.587 188.261 204.095 1.00 64.77  ? 231  ILE C CD1 1 
ATOM   6623 N N   . GLY B 2 232 ? 225.646 188.751 201.179 1.00 67.50  ? 232  GLY C N   1 
ATOM   6624 C CA  . GLY B 2 232 ? 224.671 187.718 200.898 1.00 67.50  ? 232  GLY C CA  1 
ATOM   6625 C C   . GLY B 2 232 ? 225.272 186.505 200.220 1.00 67.50  ? 232  GLY C C   1 
ATOM   6626 O O   . GLY B 2 232 ? 224.975 186.226 199.055 1.00 67.50  ? 232  GLY C O   1 
ATOM   6627 N N   . ILE B 2 233 ? 226.122 185.776 200.939 1.00 68.82  ? 233  ILE C N   1 
ATOM   6628 C CA  . ILE B 2 233 ? 226.779 184.589 200.410 1.00 68.82  ? 233  ILE C CA  1 
ATOM   6629 C C   . ILE B 2 233 ? 226.476 183.410 201.323 1.00 68.82  ? 233  ILE C C   1 
ATOM   6630 O O   . ILE B 2 233 ? 226.277 183.567 202.532 1.00 68.82  ? 233  ILE C O   1 
ATOM   6631 C CB  . ILE B 2 233 ? 228.303 184.788 200.264 1.00 68.82  ? 233  ILE C CB  1 
ATOM   6632 C CG1 . ILE B 2 233 ? 228.928 185.154 201.612 1.00 68.82  ? 233  ILE C CG1 1 
ATOM   6633 C CG2 . ILE B 2 233 ? 228.605 185.855 199.224 1.00 68.82  ? 233  ILE C CG2 1 
ATOM   6634 C CD1 . ILE B 2 233 ? 230.427 185.340 201.559 1.00 68.82  ? 233  ILE C CD1 1 
ATOM   6635 N N   . ASN B 2 234 ? 226.436 182.220 200.729 1.00 75.34  ? 234  ASN C N   1 
ATOM   6636 C CA  . ASN B 2 234 ? 226.189 180.992 201.471 1.00 75.34  ? 234  ASN C CA  1 
ATOM   6637 C C   . ASN B 2 234 ? 227.504 180.441 202.005 1.00 75.34  ? 234  ASN C C   1 
ATOM   6638 O O   . ASN B 2 234 ? 228.468 180.276 201.251 1.00 75.34  ? 234  ASN C O   1 
ATOM   6639 C CB  . ASN B 2 234 ? 225.499 179.955 200.585 1.00 75.34  ? 234  ASN C CB  1 
ATOM   6640 C CG  . ASN B 2 234 ? 224.094 180.364 200.195 1.00 75.34  ? 234  ASN C CG  1 
ATOM   6641 O OD1 . ASN B 2 234 ? 223.721 181.531 200.309 1.00 75.34  ? 234  ASN C OD1 1 
ATOM   6642 N ND2 . ASN B 2 234 ? 223.305 179.403 199.730 1.00 75.34  ? 234  ASN C ND2 1 
ATOM   6643 N N   . ILE B 2 235 ? 227.538 180.158 203.303 1.00 68.25  ? 235  ILE C N   1 
ATOM   6644 C CA  . ILE B 2 235 ? 228.726 179.641 203.972 1.00 68.25  ? 235  ILE C CA  1 
ATOM   6645 C C   . ILE B 2 235 ? 228.440 178.199 204.367 1.00 68.25  ? 235  ILE C C   1 
ATOM   6646 O O   . ILE B 2 235 ? 227.585 177.936 205.220 1.00 68.25  ? 235  ILE C O   1 
ATOM   6647 C CB  . ILE B 2 235 ? 229.109 180.488 205.192 1.00 68.25  ? 235  ILE C CB  1 
ATOM   6648 C CG1 . ILE B 2 235 ? 229.298 181.950 204.786 1.00 68.25  ? 235  ILE C CG1 1 
ATOM   6649 C CG2 . ILE B 2 235 ? 230.376 179.947 205.836 1.00 68.25  ? 235  ILE C CG2 1 
ATOM   6650 C CD1 . ILE B 2 235 ? 230.380 182.161 203.751 1.00 68.25  ? 235  ILE C CD1 1 
ATOM   6651 N N   . THR B 2 236 ? 229.154 177.266 203.748 1.00 67.83  ? 236  THR C N   1 
ATOM   6652 C CA  . THR B 2 236 ? 229.001 175.844 204.029 1.00 67.83  ? 236  THR C CA  1 
ATOM   6653 C C   . THR B 2 236 ? 230.254 175.214 204.613 1.00 67.83  ? 236  THR C C   1 
ATOM   6654 O O   . THR B 2 236 ? 230.157 174.403 205.538 1.00 67.83  ? 236  THR C O   1 
ATOM   6655 C CB  . THR B 2 236 ? 228.602 175.092 202.749 1.00 67.83  ? 236  THR C CB  1 
ATOM   6656 O OG1 . THR B 2 236 ? 227.431 175.695 202.185 1.00 67.83  ? 236  THR C OG1 1 
ATOM   6657 C CG2 . THR B 2 236 ? 228.312 173.630 203.054 1.00 67.83  ? 236  THR C CG2 1 
ATOM   6658 N N   . ARG B 2 237 ? 231.431 175.566 204.101 1.00 66.82  ? 237  ARG C N   1 
ATOM   6659 C CA  . ARG B 2 237 ? 232.690 175.042 204.605 1.00 66.82  ? 237  ARG C CA  1 
ATOM   6660 C C   . ARG B 2 237 ? 233.682 176.183 204.789 1.00 66.82  ? 237  ARG C C   1 
ATOM   6661 O O   . ARG B 2 237 ? 233.588 177.227 204.140 1.00 66.82  ? 237  ARG C O   1 
ATOM   6662 C CB  . ARG B 2 237 ? 233.281 173.982 203.665 1.00 66.82  ? 237  ARG C CB  1 
ATOM   6663 C CG  . ARG B 2 237 ? 232.369 172.797 203.402 1.00 66.82  ? 237  ARG C CG  1 
ATOM   6664 C CD  . ARG B 2 237 ? 233.122 171.663 202.727 1.00 66.82  ? 237  ARG C CD  1 
ATOM   6665 N NE  . ARG B 2 237 ? 233.852 172.113 201.546 1.00 66.82  ? 237  ARG C NE  1 
ATOM   6666 C CZ  . ARG B 2 237 ? 233.339 172.156 200.321 1.00 66.82  ? 237  ARG C CZ  1 
ATOM   6667 N NH1 . ARG B 2 237 ? 234.079 172.578 199.306 1.00 66.82  ? 237  ARG C NH1 1 
ATOM   6668 N NH2 . ARG B 2 237 ? 232.086 171.775 200.111 1.00 66.82  ? 237  ARG C NH2 1 
ATOM   6669 N N   . PHE B 2 238 ? 234.642 175.969 205.686 1.00 64.20  ? 238  PHE C N   1 
ATOM   6670 C CA  . PHE B 2 238 ? 235.669 176.961 205.966 1.00 64.20  ? 238  PHE C CA  1 
ATOM   6671 C C   . PHE B 2 238 ? 236.999 176.261 206.203 1.00 64.20  ? 238  PHE C C   1 
ATOM   6672 O O   . PHE B 2 238 ? 237.043 175.102 206.623 1.00 64.20  ? 238  PHE C O   1 
ATOM   6673 C CB  . PHE B 2 238 ? 235.304 177.831 207.178 1.00 64.20  ? 238  PHE C CB  1 
ATOM   6674 C CG  . PHE B 2 238 ? 235.467 177.136 208.499 1.00 64.20  ? 238  PHE C CG  1 
ATOM   6675 C CD1 . PHE B 2 238 ? 234.536 176.207 208.928 1.00 64.20  ? 238  PHE C CD1 1 
ATOM   6676 C CD2 . PHE B 2 238 ? 236.546 177.423 209.318 1.00 64.20  ? 238  PHE C CD2 1 
ATOM   6677 C CE1 . PHE B 2 238 ? 234.683 175.570 210.144 1.00 64.20  ? 238  PHE C CE1 1 
ATOM   6678 C CE2 . PHE B 2 238 ? 236.698 176.790 210.536 1.00 64.20  ? 238  PHE C CE2 1 
ATOM   6679 C CZ  . PHE B 2 238 ? 235.765 175.862 210.949 1.00 64.20  ? 238  PHE C CZ  1 
ATOM   6680 N N   . GLN B 2 239 ? 238.084 176.981 205.928 1.00 67.17  ? 239  GLN C N   1 
ATOM   6681 C CA  . GLN B 2 239 ? 239.434 176.458 206.077 1.00 67.17  ? 239  GLN C CA  1 
ATOM   6682 C C   . GLN B 2 239 ? 240.295 177.476 206.811 1.00 67.17  ? 239  GLN C C   1 
ATOM   6683 O O   . GLN B 2 239 ? 240.179 178.683 206.579 1.00 67.17  ? 239  GLN C O   1 
ATOM   6684 C CB  . GLN B 2 239 ? 240.054 176.124 204.715 1.00 67.17  ? 239  GLN C CB  1 
ATOM   6685 C CG  . GLN B 2 239 ? 241.358 175.350 204.797 1.00 67.17  ? 239  GLN C CG  1 
ATOM   6686 C CD  . GLN B 2 239 ? 241.867 174.923 203.435 1.00 67.17  ? 239  GLN C CD  1 
ATOM   6687 O OE1 . GLN B 2 239 ? 241.390 175.398 202.405 1.00 67.17  ? 239  GLN C OE1 1 
ATOM   6688 N NE2 . GLN B 2 239 ? 242.838 174.018 203.424 1.00 67.17  ? 239  GLN C NE2 1 
ATOM   6689 N N   . THR B 2 240 ? 241.158 176.982 207.694 1.00 66.66  ? 240  THR C N   1 
ATOM   6690 C CA  . THR B 2 240 ? 242.008 177.835 208.512 1.00 66.66  ? 240  THR C CA  1 
ATOM   6691 C C   . THR B 2 240 ? 243.319 178.128 207.795 1.00 66.66  ? 240  THR C C   1 
ATOM   6692 O O   . THR B 2 240 ? 243.928 177.236 207.197 1.00 66.66  ? 240  THR C O   1 
ATOM   6693 C CB  . THR B 2 240 ? 242.287 177.174 209.864 1.00 66.66  ? 240  THR C CB  1 
ATOM   6694 O OG1 . THR B 2 240 ? 241.047 176.845 210.501 1.00 66.66  ? 240  THR C OG1 1 
ATOM   6695 C CG2 . THR B 2 240 ? 243.077 178.109 210.767 1.00 66.66  ? 240  THR C CG2 1 
ATOM   6696 N N   . LEU B 2 241 ? 243.749 179.387 207.859 1.00 67.17  ? 241  LEU C N   1 
ATOM   6697 C CA  . LEU B 2 241 ? 244.994 179.833 207.242 1.00 67.17  ? 241  LEU C CA  1 
ATOM   6698 C C   . LEU B 2 241 ? 246.083 179.876 208.308 1.00 67.17  ? 241  LEU C C   1 
ATOM   6699 O O   . LEU B 2 241 ? 246.043 180.716 209.213 1.00 67.17  ? 241  LEU C O   1 
ATOM   6700 C CB  . LEU B 2 241 ? 244.815 181.201 206.587 1.00 67.17  ? 241  LEU C CB  1 
ATOM   6701 C CG  . LEU B 2 241 ? 243.973 181.227 205.312 1.00 67.17  ? 241  LEU C CG  1 
ATOM   6702 C CD1 . LEU B 2 241 ? 243.803 182.650 204.808 1.00 67.17  ? 241  LEU C CD1 1 
ATOM   6703 C CD2 . LEU B 2 241 ? 244.615 180.354 204.250 1.00 67.17  ? 241  LEU C CD2 1 
ATOM   6704 N N   . LEU B 2 242 ? 247.052 178.972 208.199 1.00 71.58  ? 242  LEU C N   1 
ATOM   6705 C CA  . LEU B 2 242 ? 248.171 178.906 209.123 1.00 71.58  ? 242  LEU C CA  1 
ATOM   6706 C C   . LEU B 2 242 ? 249.417 179.515 208.481 1.00 71.58  ? 242  LEU C C   1 
ATOM   6707 O O   . LEU B 2 242 ? 249.380 180.059 207.375 1.00 71.58  ? 242  LEU C O   1 
ATOM   6708 C CB  . LEU B 2 242 ? 248.423 177.460 209.553 1.00 71.58  ? 242  LEU C CB  1 
ATOM   6709 C CG  . LEU B 2 242 ? 247.250 176.716 210.194 1.00 71.58  ? 242  LEU C CG  1 
ATOM   6710 C CD1 . LEU B 2 242 ? 247.654 175.298 210.563 1.00 71.58  ? 242  LEU C CD1 1 
ATOM   6711 C CD2 . LEU B 2 242 ? 246.743 177.465 211.414 1.00 71.58  ? 242  LEU C CD2 1 
ATOM   6712 N N   . ALA B 2 243 ? 250.538 179.417 209.192 1.00 78.00  ? 243  ALA C N   1 
ATOM   6713 C CA  . ALA B 2 243 ? 251.812 179.937 208.720 1.00 78.00  ? 243  ALA C CA  1 
ATOM   6714 C C   . ALA B 2 243 ? 252.892 178.878 208.885 1.00 78.00  ? 243  ALA C C   1 
ATOM   6715 O O   . ALA B 2 243 ? 252.746 177.923 209.652 1.00 78.00  ? 243  ALA C O   1 
ATOM   6716 C CB  . ALA B 2 243 ? 252.211 181.217 209.467 1.00 78.00  ? 243  ALA C CB  1 
ATOM   6717 N N   . LEU B 2 244 ? 253.988 179.059 208.150 1.00 85.09  ? 244  LEU C N   1 
ATOM   6718 C CA  . LEU B 2 244 ? 255.114 178.140 208.182 1.00 85.09  ? 244  LEU C CA  1 
ATOM   6719 C C   . LEU B 2 244 ? 256.417 178.915 208.310 1.00 85.09  ? 244  LEU C C   1 
ATOM   6720 O O   . LEU B 2 244 ? 256.536 180.048 207.836 1.00 85.09  ? 244  LEU C O   1 
ATOM   6721 C CB  . LEU B 2 244 ? 255.159 177.257 206.929 1.00 85.09  ? 244  LEU C CB  1 
ATOM   6722 C CG  . LEU B 2 244 ? 254.185 176.079 206.917 1.00 85.09  ? 244  LEU C CG  1 
ATOM   6723 C CD1 . LEU B 2 244 ? 254.349 175.258 205.650 1.00 85.09  ? 244  LEU C CD1 1 
ATOM   6724 C CD2 . LEU B 2 244 ? 254.400 175.218 208.149 1.00 85.09  ? 244  LEU C CD2 1 
ATOM   6725 N N   . HIS B 2 245 ? 257.394 178.288 208.957 1.00 88.70  ? 245  HIS C N   1 
ATOM   6726 C CA  . HIS B 2 245 ? 258.715 178.867 209.153 1.00 88.70  ? 245  HIS C CA  1 
ATOM   6727 C C   . HIS B 2 245 ? 259.716 178.195 208.223 1.00 88.70  ? 245  HIS C C   1 
ATOM   6728 O O   . HIS B 2 245 ? 259.684 176.974 208.039 1.00 88.70  ? 245  HIS C O   1 
ATOM   6729 C CB  . HIS B 2 245 ? 259.173 178.718 210.606 1.00 88.70  ? 245  HIS C CB  1 
ATOM   6730 C CG  . HIS B 2 245 ? 258.212 179.283 211.605 1.00 88.70  ? 245  HIS C CG  1 
ATOM   6731 N ND1 . HIS B 2 245 ? 258.264 180.593 212.028 1.00 88.70  ? 245  HIS C ND1 1 
ATOM   6732 C CD2 . HIS B 2 245 ? 257.177 178.715 212.267 1.00 88.70  ? 245  HIS C CD2 1 
ATOM   6733 C CE1 . HIS B 2 245 ? 257.301 180.809 212.906 1.00 88.70  ? 245  HIS C CE1 1 
ATOM   6734 N NE2 . HIS B 2 245 ? 256.627 179.684 213.069 1.00 88.70  ? 245  HIS C NE2 1 
ATOM   6735 N N   . ARG B 2 246 ? 260.600 178.998 207.637 1.00 95.28  ? 246  ARG C N   1 
ATOM   6736 C CA  . ARG B 2 246 ? 261.641 178.499 206.751 1.00 95.28  ? 246  ARG C CA  1 
ATOM   6737 C C   . ARG B 2 246 ? 262.950 179.201 207.075 1.00 95.28  ? 246  ARG C C   1 
ATOM   6738 O O   . ARG B 2 246 ? 262.964 180.398 207.370 1.00 95.28  ? 246  ARG C O   1 
ATOM   6739 C CB  . ARG B 2 246 ? 261.278 178.715 205.276 1.00 95.28  ? 246  ARG C CB  1 
ATOM   6740 C CG  . ARG B 2 246 ? 260.077 177.912 204.806 1.00 95.28  ? 246  ARG C CG  1 
ATOM   6741 C CD  . ARG B 2 246 ? 259.811 178.131 203.326 1.00 95.28  ? 246  ARG C CD  1 
ATOM   6742 N NE  . ARG B 2 246 ? 258.695 177.321 202.847 1.00 95.28  ? 246  ARG C NE  1 
ATOM   6743 C CZ  . ARG B 2 246 ? 258.262 177.316 201.591 1.00 95.28  ? 246  ARG C CZ  1 
ATOM   6744 N NH1 . ARG B 2 246 ? 257.240 176.547 201.243 1.00 95.28  ? 246  ARG C NH1 1 
ATOM   6745 N NH2 . ARG B 2 246 ? 258.850 178.082 200.681 1.00 95.28  ? 246  ARG C NH2 1 
ATOM   6746 N N   . SER B 2 247 ? 264.045 178.449 207.021 1.00 103.76 ? 247  SER C N   1 
ATOM   6747 C CA  . SER B 2 247 ? 265.365 178.987 207.322 1.00 103.76 ? 247  SER C CA  1 
ATOM   6748 C C   . SER B 2 247 ? 266.399 178.192 206.534 1.00 103.76 ? 247  SER C C   1 
ATOM   6749 O O   . SER B 2 247 ? 266.058 177.391 205.659 1.00 103.76 ? 247  SER C O   1 
ATOM   6750 C CB  . SER B 2 247 ? 265.632 178.951 208.832 1.00 103.76 ? 247  SER C CB  1 
ATOM   6751 O OG  . SER B 2 247 ? 266.911 179.477 209.137 1.00 103.76 ? 247  SER C OG  1 
ATOM   6752 N N   . TYR B 2 248 ? 267.677 178.419 206.847 1.00 109.06 ? 248  TYR C N   1 
ATOM   6753 C CA  . TYR B 2 248 ? 268.741 177.689 206.169 1.00 109.06 ? 248  TYR C CA  1 
ATOM   6754 C C   . TYR B 2 248 ? 268.800 176.236 206.621 1.00 109.06 ? 248  TYR C C   1 
ATOM   6755 O O   . TYR B 2 248 ? 269.220 175.365 205.849 1.00 109.06 ? 248  TYR C O   1 
ATOM   6756 C CB  . TYR B 2 248 ? 270.087 178.375 206.406 1.00 109.06 ? 248  TYR C CB  1 
ATOM   6757 C CG  . TYR B 2 248 ? 270.498 178.453 207.861 1.00 109.06 ? 248  TYR C CG  1 
ATOM   6758 C CD1 . TYR B 2 248 ? 271.290 177.465 208.433 1.00 109.06 ? 248  TYR C CD1 1 
ATOM   6759 C CD2 . TYR B 2 248 ? 270.098 179.516 208.660 1.00 109.06 ? 248  TYR C CD2 1 
ATOM   6760 C CE1 . TYR B 2 248 ? 271.668 177.533 209.760 1.00 109.06 ? 248  TYR C CE1 1 
ATOM   6761 C CE2 . TYR B 2 248 ? 270.471 179.591 209.988 1.00 109.06 ? 248  TYR C CE2 1 
ATOM   6762 C CZ  . TYR B 2 248 ? 271.256 178.598 210.533 1.00 109.06 ? 248  TYR C CZ  1 
ATOM   6763 O OH  . TYR B 2 248 ? 271.631 178.669 211.855 1.00 109.06 ? 248  TYR C OH  1 
ATOM   6764 N N   . LEU B 2 249 ? 268.388 175.954 207.853 1.00 104.87 ? 249  LEU C N   1 
ATOM   6765 C CA  . LEU B 2 249 ? 268.388 174.590 208.381 1.00 104.87 ? 249  LEU C CA  1 
ATOM   6766 C C   . LEU B 2 249 ? 267.056 173.894 208.112 1.00 104.87 ? 249  LEU C C   1 
ATOM   6767 O O   . LEU B 2 249 ? 266.403 173.369 209.013 1.00 104.87 ? 249  LEU C O   1 
ATOM   6768 C CB  . LEU B 2 249 ? 268.709 174.613 209.871 1.00 104.87 ? 249  LEU C CB  1 
ATOM   6769 C CG  . LEU B 2 249 ? 269.184 173.305 210.508 1.00 104.87 ? 249  LEU C CG  1 
ATOM   6770 C CD1 . LEU B 2 249 ? 270.465 172.819 209.846 1.00 104.87 ? 249  LEU C CD1 1 
ATOM   6771 C CD2 . LEU B 2 249 ? 269.381 173.476 212.006 1.00 104.87 ? 249  LEU C CD2 1 
ATOM   6772 N N   . THR B 2 250 ? 266.641 173.896 206.846 1.00 102.93 ? 250  THR C N   1 
ATOM   6773 C CA  . THR B 2 250 ? 265.391 173.265 206.425 1.00 102.93 ? 250  THR C CA  1 
ATOM   6774 C C   . THR B 2 250 ? 265.641 172.521 205.119 1.00 102.93 ? 250  THR C C   1 
ATOM   6775 O O   . THR B 2 250 ? 265.717 173.143 204.047 1.00 102.93 ? 250  THR C O   1 
ATOM   6776 C CB  . THR B 2 250 ? 264.270 174.289 206.259 1.00 102.93 ? 250  THR C CB  1 
ATOM   6777 O OG1 . THR B 2 250 ? 264.724 175.368 205.432 1.00 102.93 ? 250  THR C OG1 1 
ATOM   6778 C CG2 . THR B 2 250 ? 263.829 174.836 207.611 1.00 102.93 ? 250  THR C CG2 1 
ATOM   6779 N N   . PRO B 2 251 ? 265.777 171.195 205.165 1.00 104.27 ? 251  PRO C N   1 
ATOM   6780 C CA  . PRO B 2 251 ? 265.998 170.425 203.930 1.00 104.27 ? 251  PRO C CA  1 
ATOM   6781 C C   . PRO B 2 251 ? 264.734 170.387 203.083 1.00 104.27 ? 251  PRO C C   1 
ATOM   6782 O O   . PRO B 2 251 ? 263.711 169.835 203.494 1.00 104.27 ? 251  PRO C O   1 
ATOM   6783 C CB  . PRO B 2 251 ? 266.382 169.033 204.445 1.00 104.27 ? 251  PRO C CB  1 
ATOM   6784 C CG  . PRO B 2 251 ? 265.753 168.949 205.797 1.00 104.27 ? 251  PRO C CG  1 
ATOM   6785 C CD  . PRO B 2 251 ? 265.794 170.341 206.365 1.00 104.27 ? 251  PRO C CD  1 
ATOM   6786 N N   . GLY B 2 252 ? 264.812 170.976 201.893 1.00 101.35 ? 252  GLY C N   1 
ATOM   6787 C CA  . GLY B 2 252 ? 263.678 171.022 200.992 1.00 101.35 ? 252  GLY C CA  1 
ATOM   6788 C C   . GLY B 2 252 ? 263.790 172.137 199.974 1.00 101.35 ? 252  GLY C C   1 
ATOM   6789 O O   . GLY B 2 252 ? 264.422 173.164 200.240 1.00 101.35 ? 252  GLY C O   1 
ATOM   6790 N N   . ASP B 2 253 ? 263.183 171.952 198.802 1.00 106.10 ? 253  ASP C N   1 
ATOM   6791 C CA  . ASP B 2 253 ? 263.262 172.929 197.724 1.00 106.10 ? 253  ASP C CA  1 
ATOM   6792 C C   . ASP B 2 253 ? 261.915 173.577 197.427 1.00 106.10 ? 253  ASP C C   1 
ATOM   6793 O O   . ASP B 2 253 ? 261.798 174.805 197.472 1.00 106.10 ? 253  ASP C O   1 
ATOM   6794 C CB  . ASP B 2 253 ? 263.832 172.267 196.461 1.00 106.10 ? 253  ASP C CB  1 
ATOM   6795 C CG  . ASP B 2 253 ? 263.154 170.950 196.133 1.00 106.10 ? 253  ASP C CG  1 
ATOM   6796 O OD1 . ASP B 2 253 ? 262.260 170.533 196.900 1.00 106.10 ? 253  ASP C OD1 1 
ATOM   6797 O OD2 . ASP B 2 253 ? 263.515 170.333 195.110 1.00 106.10 ? 253  ASP C OD2 1 
ATOM   6798 N N   . SER B 2 254 ? 260.887 172.784 197.124 1.00 99.43  ? 254  SER C N   1 
ATOM   6799 C CA  . SER B 2 254 ? 259.576 173.322 196.777 1.00 99.43  ? 254  SER C CA  1 
ATOM   6800 C C   . SER B 2 254 ? 258.508 172.929 197.788 1.00 99.43  ? 254  SER C C   1 
ATOM   6801 O O   . SER B 2 254 ? 257.843 173.807 198.347 1.00 99.43  ? 254  SER C O   1 
ATOM   6802 C CB  . SER B 2 254 ? 259.179 172.864 195.367 1.00 99.43  ? 254  SER C CB  1 
ATOM   6803 O OG  . SER B 2 254 ? 259.116 171.451 195.290 1.00 99.43  ? 254  SER C OG  1 
ATOM   6804 N N   . SER B 2 255 ? 258.324 171.634 198.045 1.00 94.86  ? 255  SER C N   1 
ATOM   6805 C CA  . SER B 2 255 ? 257.277 171.180 198.951 1.00 94.86  ? 255  SER C CA  1 
ATOM   6806 C C   . SER B 2 255 ? 257.776 170.970 200.372 1.00 94.86  ? 255  SER C C   1 
ATOM   6807 O O   . SER B 2 255 ? 257.018 171.190 201.324 1.00 94.86  ? 255  SER C O   1 
ATOM   6808 C CB  . SER B 2 255 ? 256.658 169.880 198.431 1.00 94.86  ? 255  SER C CB  1 
ATOM   6809 O OG  . SER B 2 255 ? 255.652 169.407 199.309 1.00 94.86  ? 255  SER C OG  1 
ATOM   6810 N N   . SER B 2 256 ? 259.022 170.545 200.540 1.00 95.60  ? 256  SER C N   1 
ATOM   6811 C CA  . SER B 2 256 ? 259.614 170.346 201.850 1.00 95.60  ? 256  SER C CA  1 
ATOM   6812 C C   . SER B 2 256 ? 260.427 171.580 202.238 1.00 95.60  ? 256  SER C C   1 
ATOM   6813 O O   . SER B 2 256 ? 260.406 172.608 201.554 1.00 95.60  ? 256  SER C O   1 
ATOM   6814 C CB  . SER B 2 256 ? 260.465 169.075 201.853 1.00 95.60  ? 256  SER C CB  1 
ATOM   6815 O OG  . SER B 2 256 ? 259.682 167.938 201.531 1.00 95.60  ? 256  SER C OG  1 
ATOM   6816 N N   . GLY B 2 257 ? 261.152 171.483 203.347 1.00 97.34  ? 257  GLY C N   1 
ATOM   6817 C CA  . GLY B 2 257 ? 261.975 172.589 203.797 1.00 97.34  ? 257  GLY C CA  1 
ATOM   6818 C C   . GLY B 2 257 ? 261.239 173.625 204.614 1.00 97.34  ? 257  GLY C C   1 
ATOM   6819 O O   . GLY B 2 257 ? 261.483 174.827 204.450 1.00 97.34  ? 257  GLY C O   1 
ATOM   6820 N N   . TRP B 2 258 ? 260.339 173.195 205.496 1.00 91.08  ? 258  TRP C N   1 
ATOM   6821 C CA  . TRP B 2 258 ? 259.579 174.119 206.321 1.00 91.08  ? 258  TRP C CA  1 
ATOM   6822 C C   . TRP B 2 258 ? 259.300 173.476 207.670 1.00 91.08  ? 258  TRP C C   1 
ATOM   6823 O O   . TRP B 2 258 ? 259.412 172.259 207.837 1.00 91.08  ? 258  TRP C O   1 
ATOM   6824 C CB  . TRP B 2 258 ? 258.267 174.533 205.643 1.00 91.08  ? 258  TRP C CB  1 
ATOM   6825 C CG  . TRP B 2 258 ? 257.513 173.385 205.045 1.00 91.08  ? 258  TRP C CG  1 
ATOM   6826 C CD1 . TRP B 2 258 ? 257.543 172.976 203.745 1.00 91.08  ? 258  TRP C CD1 1 
ATOM   6827 C CD2 . TRP B 2 258 ? 256.617 172.497 205.725 1.00 91.08  ? 258  TRP C CD2 1 
ATOM   6828 N NE1 . TRP B 2 258 ? 256.722 171.889 203.571 1.00 91.08  ? 258  TRP C NE1 1 
ATOM   6829 C CE2 . TRP B 2 258 ? 256.141 171.575 204.772 1.00 91.08  ? 258  TRP C CE2 1 
ATOM   6830 C CE3 . TRP B 2 258 ? 256.171 172.391 207.045 1.00 91.08  ? 258  TRP C CE3 1 
ATOM   6831 C CZ2 . TRP B 2 258 ? 255.242 170.562 205.097 1.00 91.08  ? 258  TRP C CZ2 1 
ATOM   6832 C CZ3 . TRP B 2 258 ? 255.278 171.386 207.366 1.00 91.08  ? 258  TRP C CZ3 1 
ATOM   6833 C CH2 . TRP B 2 258 ? 254.824 170.484 206.397 1.00 91.08  ? 258  TRP C CH2 1 
ATOM   6834 N N   . THR B 2 259 ? 258.935 174.316 208.634 1.00 89.33  ? 259  THR C N   1 
ATOM   6835 C CA  . THR B 2 259 ? 258.598 173.871 209.977 1.00 89.33  ? 259  THR C CA  1 
ATOM   6836 C C   . THR B 2 259 ? 257.444 174.709 210.504 1.00 89.33  ? 259  THR C C   1 
ATOM   6837 O O   . THR B 2 259 ? 257.363 175.910 210.231 1.00 89.33  ? 259  THR C O   1 
ATOM   6838 C CB  . THR B 2 259 ? 259.800 173.971 210.928 1.00 89.33  ? 259  THR C CB  1 
ATOM   6839 O OG1 . THR B 2 259 ? 259.354 173.843 212.283 1.00 89.33  ? 259  THR C OG1 1 
ATOM   6840 C CG2 . THR B 2 259 ? 260.514 175.303 210.754 1.00 89.33  ? 259  THR C CG2 1 
ATOM   6841 N N   . ALA B 2 260 ? 256.553 174.070 211.254 1.00 84.85  ? 260  ALA C N   1 
ATOM   6842 C CA  . ALA B 2 260 ? 255.381 174.727 211.812 1.00 84.85  ? 260  ALA C CA  1 
ATOM   6843 C C   . ALA B 2 260 ? 255.607 175.008 213.291 1.00 84.85  ? 260  ALA C C   1 
ATOM   6844 O O   . ALA B 2 260 ? 255.930 174.096 214.059 1.00 84.85  ? 260  ALA C O   1 
ATOM   6845 C CB  . ALA B 2 260 ? 254.130 173.868 211.622 1.00 84.85  ? 260  ALA C CB  1 
ATOM   6846 N N   . GLY B 2 261 ? 255.442 176.270 213.683 1.00 79.77  ? 261  GLY C N   1 
ATOM   6847 C CA  . GLY B 2 261 ? 255.575 176.628 215.077 1.00 79.77  ? 261  GLY C CA  1 
ATOM   6848 C C   . GLY B 2 261 ? 254.479 176.023 215.932 1.00 79.77  ? 261  GLY C C   1 
ATOM   6849 O O   . GLY B 2 261 ? 253.414 175.632 215.453 1.00 79.77  ? 261  GLY C O   1 
ATOM   6850 N N   . ALA B 2 262 ? 254.756 175.945 217.233 1.00 78.55  ? 262  ALA C N   1 
ATOM   6851 C CA  . ALA B 2 262 ? 253.819 175.355 218.180 1.00 78.55  ? 262  ALA C CA  1 
ATOM   6852 C C   . ALA B 2 262 ? 252.519 176.147 218.231 1.00 78.55  ? 262  ALA C C   1 
ATOM   6853 O O   . ALA B 2 262 ? 252.496 177.288 218.704 1.00 78.55  ? 262  ALA C O   1 
ATOM   6854 C CB  . ALA B 2 262 ? 254.446 175.273 219.574 1.00 78.55  ? 262  ALA C CB  1 
ATOM   6855 N N   . ALA B 2 263 ? 251.434 175.548 217.746 1.00 72.93  ? 263  ALA C N   1 
ATOM   6856 C CA  . ALA B 2 263 ? 250.134 176.204 217.736 1.00 72.93  ? 263  ALA C CA  1 
ATOM   6857 C C   . ALA B 2 263 ? 249.050 175.143 217.633 1.00 72.93  ? 263  ALA C C   1 
ATOM   6858 O O   . ALA B 2 263 ? 249.287 174.031 217.156 1.00 72.93  ? 263  ALA C O   1 
ATOM   6859 C CB  . ALA B 2 263 ? 250.017 177.209 216.585 1.00 72.93  ? 263  ALA C CB  1 
ATOM   6860 N N   . ALA B 2 264 ? 247.854 175.507 218.088 1.00 68.33  ? 264  ALA C N   1 
ATOM   6861 C CA  . ALA B 2 264 ? 246.714 174.604 218.053 1.00 68.33  ? 264  ALA C CA  1 
ATOM   6862 C C   . ALA B 2 264 ? 245.436 175.425 218.135 1.00 68.33  ? 264  ALA C C   1 
ATOM   6863 O O   . ALA B 2 264 ? 245.348 176.366 218.928 1.00 68.33  ? 264  ALA C O   1 
ATOM   6864 C CB  . ALA B 2 264 ? 246.769 173.587 219.198 1.00 68.33  ? 264  ALA C CB  1 
ATOM   6865 N N   . TYR B 2 265 ? 244.454 175.065 217.313 1.00 66.99  ? 265  TYR C N   1 
ATOM   6866 C CA  . TYR B 2 265 ? 243.174 175.755 217.286 1.00 66.99  ? 265  TYR C CA  1 
ATOM   6867 C C   . TYR B 2 265 ? 242.044 174.758 217.496 1.00 66.99  ? 265  TYR C C   1 
ATOM   6868 O O   . TYR B 2 265 ? 242.168 173.573 217.174 1.00 66.99  ? 265  TYR C O   1 
ATOM   6869 C CB  . TYR B 2 265 ? 242.967 176.520 215.970 1.00 66.99  ? 265  TYR C CB  1 
ATOM   6870 C CG  . TYR B 2 265 ? 243.029 175.666 214.723 1.00 66.99  ? 265  TYR C CG  1 
ATOM   6871 C CD1 . TYR B 2 265 ? 244.245 175.362 214.126 1.00 66.99  ? 265  TYR C CD1 1 
ATOM   6872 C CD2 . TYR B 2 265 ? 241.870 175.180 214.133 1.00 66.99  ? 265  TYR C CD2 1 
ATOM   6873 C CE1 . TYR B 2 265 ? 244.306 174.588 212.984 1.00 66.99  ? 265  TYR C CE1 1 
ATOM   6874 C CE2 . TYR B 2 265 ? 241.921 174.407 212.990 1.00 66.99  ? 265  TYR C CE2 1 
ATOM   6875 C CZ  . TYR B 2 265 ? 243.141 174.114 212.420 1.00 66.99  ? 265  TYR C CZ  1 
ATOM   6876 O OH  . TYR B 2 265 ? 243.197 173.343 211.282 1.00 66.99  ? 265  TYR C OH  1 
ATOM   6877 N N   . TYR B 2 266 ? 240.938 175.256 218.041 1.00 68.72  ? 266  TYR C N   1 
ATOM   6878 C CA  . TYR B 2 266 ? 239.778 174.444 218.375 1.00 68.72  ? 266  TYR C CA  1 
ATOM   6879 C C   . TYR B 2 266 ? 238.565 174.949 217.607 1.00 68.72  ? 266  TYR C C   1 
ATOM   6880 O O   . TYR B 2 266 ? 238.398 176.157 217.417 1.00 68.72  ? 266  TYR C O   1 
ATOM   6881 C CB  . TYR B 2 266 ? 239.498 174.480 219.881 1.00 68.72  ? 266  TYR C CB  1 
ATOM   6882 C CG  . TYR B 2 266 ? 240.640 173.968 220.731 1.00 68.72  ? 266  TYR C CG  1 
ATOM   6883 C CD1 . TYR B 2 266 ? 240.660 172.655 221.182 1.00 68.72  ? 266  TYR C CD1 1 
ATOM   6884 C CD2 . TYR B 2 266 ? 241.697 174.797 221.083 1.00 68.72  ? 266  TYR C CD2 1 
ATOM   6885 C CE1 . TYR B 2 266 ? 241.700 172.182 221.958 1.00 68.72  ? 266  TYR C CE1 1 
ATOM   6886 C CE2 . TYR B 2 266 ? 242.742 174.332 221.858 1.00 68.72  ? 266  TYR C CE2 1 
ATOM   6887 C CZ  . TYR B 2 266 ? 242.738 173.025 222.293 1.00 68.72  ? 266  TYR C CZ  1 
ATOM   6888 O OH  . TYR B 2 266 ? 243.776 172.559 223.066 1.00 68.72  ? 266  TYR C OH  1 
ATOM   6889 N N   . VAL B 2 267 ? 237.720 174.019 217.166 1.00 64.93  ? 267  VAL C N   1 
ATOM   6890 C CA  . VAL B 2 267 ? 236.535 174.337 216.377 1.00 64.93  ? 267  VAL C CA  1 
ATOM   6891 C C   . VAL B 2 267 ? 235.334 173.658 217.019 1.00 64.93  ? 267  VAL C C   1 
ATOM   6892 O O   . VAL B 2 267 ? 235.293 172.426 217.118 1.00 64.93  ? 267  VAL C O   1 
ATOM   6893 C CB  . VAL B 2 267 ? 236.681 173.900 214.910 1.00 64.93  ? 267  VAL C CB  1 
ATOM   6894 C CG1 . VAL B 2 267 ? 235.385 174.144 214.155 1.00 64.93  ? 267  VAL C CG1 1 
ATOM   6895 C CG2 . VAL B 2 267 ? 237.834 174.638 214.249 1.00 64.93  ? 267  VAL C CG2 1 
ATOM   6896 N N   . GLY B 2 268 ? 234.360 174.457 217.449 1.00 61.88  ? 268  GLY C N   1 
ATOM   6897 C CA  . GLY B 2 268 ? 233.131 173.933 218.012 1.00 61.88  ? 268  GLY C CA  1 
ATOM   6898 C C   . GLY B 2 268 ? 231.904 174.472 217.308 1.00 61.88  ? 268  GLY C C   1 
ATOM   6899 O O   . GLY B 2 268 ? 231.808 175.676 217.054 1.00 61.88  ? 268  GLY C O   1 
ATOM   6900 N N   . TYR B 2 269 ? 230.955 173.595 216.990 1.00 61.64  ? 269  TYR C N   1 
ATOM   6901 C CA  . TYR B 2 269 ? 229.774 173.978 216.230 1.00 61.64  ? 269  TYR C CA  1 
ATOM   6902 C C   . TYR B 2 269 ? 228.660 174.440 217.159 1.00 61.64  ? 269  TYR C C   1 
ATOM   6903 O O   . TYR B 2 269 ? 228.456 173.876 218.237 1.00 61.64  ? 269  TYR C O   1 
ATOM   6904 C CB  . TYR B 2 269 ? 229.290 172.812 215.368 1.00 61.64  ? 269  TYR C CB  1 
ATOM   6905 C CG  . TYR B 2 269 ? 230.342 172.285 214.421 1.00 61.64  ? 269  TYR C CG  1 
ATOM   6906 C CD1 . TYR B 2 269 ? 230.577 172.904 213.201 1.00 61.64  ? 269  TYR C CD1 1 
ATOM   6907 C CD2 . TYR B 2 269 ? 231.103 171.171 214.748 1.00 61.64  ? 269  TYR C CD2 1 
ATOM   6908 C CE1 . TYR B 2 269 ? 231.540 172.428 212.333 1.00 61.64  ? 269  TYR C CE1 1 
ATOM   6909 C CE2 . TYR B 2 269 ? 232.068 170.687 213.886 1.00 61.64  ? 269  TYR C CE2 1 
ATOM   6910 C CZ  . TYR B 2 269 ? 232.282 171.320 212.680 1.00 61.64  ? 269  TYR C CZ  1 
ATOM   6911 O OH  . TYR B 2 269 ? 233.242 170.842 211.818 1.00 61.64  ? 269  TYR C OH  1 
ATOM   6912 N N   . LEU B 2 270 ? 227.938 175.471 216.728 1.00 61.76  ? 270  LEU C N   1 
ATOM   6913 C CA  . LEU B 2 270 ? 226.862 176.034 217.528 1.00 61.76  ? 270  LEU C CA  1 
ATOM   6914 C C   . LEU B 2 270 ? 225.575 175.237 217.347 1.00 61.76  ? 270  LEU C C   1 
ATOM   6915 O O   . LEU B 2 270 ? 225.343 174.615 216.307 1.00 61.76  ? 270  LEU C O   1 
ATOM   6916 C CB  . LEU B 2 270 ? 226.621 177.496 217.151 1.00 61.76  ? 270  LEU C CB  1 
ATOM   6917 C CG  . LEU B 2 270 ? 227.808 178.452 217.283 1.00 61.76  ? 270  LEU C CG  1 
ATOM   6918 C CD1 . LEU B 2 270 ? 227.408 179.859 216.871 1.00 61.76  ? 270  LEU C CD1 1 
ATOM   6919 C CD2 . LEU B 2 270 ? 228.353 178.440 218.701 1.00 61.76  ? 270  LEU C CD2 1 
ATOM   6920 N N   . GLN B 2 271 ? 224.734 175.265 218.381 1.00 63.03  ? 271  GLN C N   1 
ATOM   6921 C CA  . GLN B 2 271 ? 223.440 174.602 218.372 1.00 63.03  ? 271  GLN C CA  1 
ATOM   6922 C C   . GLN B 2 271 ? 222.416 175.512 219.037 1.00 63.03  ? 271  GLN C C   1 
ATOM   6923 O O   . GLN B 2 271 ? 222.740 176.196 220.019 1.00 63.03  ? 271  GLN C O   1 
ATOM   6924 C CB  . GLN B 2 271 ? 223.481 173.252 219.101 1.00 63.03  ? 271  GLN C CB  1 
ATOM   6925 C CG  . GLN B 2 271 ? 224.375 172.213 218.447 1.00 63.03  ? 271  GLN C CG  1 
ATOM   6926 C CD  . GLN B 2 271 ? 224.370 170.893 219.190 1.00 63.03  ? 271  GLN C CD  1 
ATOM   6927 O OE1 . GLN B 2 271 ? 223.680 170.738 220.198 1.00 63.03  ? 271  GLN C OE1 1 
ATOM   6928 N NE2 . GLN B 2 271 ? 225.141 169.932 218.696 1.00 63.03  ? 271  GLN C NE2 1 
ATOM   6929 N N   . PRO B 2 272 ? 221.183 175.547 218.527 1.00 63.09  ? 272  PRO C N   1 
ATOM   6930 C CA  . PRO B 2 272 ? 220.153 176.395 219.144 1.00 63.09  ? 272  PRO C CA  1 
ATOM   6931 C C   . PRO B 2 272 ? 219.739 175.896 220.519 1.00 63.09  ? 272  PRO C C   1 
ATOM   6932 O O   . PRO B 2 272 ? 219.115 174.837 220.637 1.00 63.09  ? 272  PRO C O   1 
ATOM   6933 C CB  . PRO B 2 272 ? 218.987 176.319 218.148 1.00 63.09  ? 272  PRO C CB  1 
ATOM   6934 C CG  . PRO B 2 272 ? 219.585 175.801 216.874 1.00 63.09  ? 272  PRO C CG  1 
ATOM   6935 C CD  . PRO B 2 272 ? 220.704 174.907 217.292 1.00 63.09  ? 272  PRO C CD  1 
ATOM   6936 N N   . ARG B 2 273 ? 220.079 176.649 221.564 1.00 65.55  ? 273  ARG C N   1 
ATOM   6937 C CA  . ARG B 2 273 ? 219.732 176.284 222.929 1.00 65.55  ? 273  ARG C CA  1 
ATOM   6938 C C   . ARG B 2 273 ? 219.344 177.536 223.704 1.00 65.55  ? 273  ARG C C   1 
ATOM   6939 O O   . ARG B 2 273 ? 219.469 178.662 223.217 1.00 65.55  ? 273  ARG C O   1 
ATOM   6940 C CB  . ARG B 2 273 ? 220.884 175.555 223.633 1.00 65.55  ? 273  ARG C CB  1 
ATOM   6941 C CG  . ARG B 2 273 ? 221.125 174.141 223.131 1.00 65.55  ? 273  ARG C CG  1 
ATOM   6942 C CD  . ARG B 2 273 ? 222.095 173.393 224.029 1.00 65.55  ? 273  ARG C CD  1 
ATOM   6943 N NE  . ARG B 2 273 ? 222.251 172.001 223.619 1.00 65.55  ? 273  ARG C NE  1 
ATOM   6944 C CZ  . ARG B 2 273 ? 222.976 171.104 224.279 1.00 65.55  ? 273  ARG C CZ  1 
ATOM   6945 N NH1 . ARG B 2 273 ? 223.061 169.859 223.832 1.00 65.55  ? 273  ARG C NH1 1 
ATOM   6946 N NH2 . ARG B 2 273 ? 223.616 171.452 225.387 1.00 65.55  ? 273  ARG C NH2 1 
ATOM   6947 N N   . THR B 2 274 ? 218.867 177.323 224.927 1.00 65.67  ? 274  THR C N   1 
ATOM   6948 C CA  . THR B 2 274 ? 218.458 178.401 225.816 1.00 65.67  ? 274  THR C CA  1 
ATOM   6949 C C   . THR B 2 274 ? 219.524 178.612 226.883 1.00 65.67  ? 274  THR C C   1 
ATOM   6950 O O   . THR B 2 274 ? 219.952 177.656 227.537 1.00 65.67  ? 274  THR C O   1 
ATOM   6951 C CB  . THR B 2 274 ? 217.111 178.089 226.471 1.00 65.67  ? 274  THR C CB  1 
ATOM   6952 O OG1 . THR B 2 274 ? 216.123 177.873 225.456 1.00 65.67  ? 274  THR C OG1 1 
ATOM   6953 C CG2 . THR B 2 274 ? 216.671 179.241 227.361 1.00 65.67  ? 274  THR C CG2 1 
ATOM   6954 N N   . PHE B 2 275 ? 219.950 179.862 227.052 1.00 66.76  ? 275  PHE C N   1 
ATOM   6955 C CA  . PHE B 2 275 ? 220.982 180.216 228.015 1.00 66.76  ? 275  PHE C CA  1 
ATOM   6956 C C   . PHE B 2 275 ? 220.501 181.363 228.891 1.00 66.76  ? 275  PHE C C   1 
ATOM   6957 O O   . PHE B 2 275 ? 219.866 182.304 228.406 1.00 66.76  ? 275  PHE C O   1 
ATOM   6958 C CB  . PHE B 2 275 ? 222.288 180.610 227.312 1.00 66.76  ? 275  PHE C CB  1 
ATOM   6959 C CG  . PHE B 2 275 ? 223.101 179.439 226.841 1.00 66.76  ? 275  PHE C CG  1 
ATOM   6960 C CD1 . PHE B 2 275 ? 222.701 178.695 225.745 1.00 66.76  ? 275  PHE C CD1 1 
ATOM   6961 C CD2 . PHE B 2 275 ? 224.271 179.087 227.492 1.00 66.76  ? 275  PHE C CD2 1 
ATOM   6962 C CE1 . PHE B 2 275 ? 223.448 177.617 225.312 1.00 66.76  ? 275  PHE C CE1 1 
ATOM   6963 C CE2 . PHE B 2 275 ? 225.024 178.012 227.062 1.00 66.76  ? 275  PHE C CE2 1 
ATOM   6964 C CZ  . PHE B 2 275 ? 224.612 177.277 225.970 1.00 66.76  ? 275  PHE C CZ  1 
ATOM   6965 N N   . LEU B 2 276 ? 220.808 181.276 230.183 1.00 66.36  ? 276  LEU C N   1 
ATOM   6966 C CA  . LEU B 2 276 ? 220.491 182.326 231.145 1.00 66.36  ? 276  LEU C CA  1 
ATOM   6967 C C   . LEU B 2 276 ? 221.760 183.130 231.403 1.00 66.36  ? 276  LEU C C   1 
ATOM   6968 O O   . LEU B 2 276 ? 222.675 182.657 232.085 1.00 66.36  ? 276  LEU C O   1 
ATOM   6969 C CB  . LEU B 2 276 ? 219.938 181.740 232.442 1.00 66.36  ? 276  LEU C CB  1 
ATOM   6970 C CG  . LEU B 2 276 ? 218.451 181.376 232.496 1.00 66.36  ? 276  LEU C CG  1 
ATOM   6971 C CD1 . LEU B 2 276 ? 218.129 180.179 231.613 1.00 66.36  ? 276  LEU C CD1 1 
ATOM   6972 C CD2 . LEU B 2 276 ? 218.020 181.117 233.932 1.00 66.36  ? 276  LEU C CD2 1 
ATOM   6973 N N   . LEU B 2 277 ? 221.812 184.343 230.860 1.00 66.45  ? 277  LEU C N   1 
ATOM   6974 C CA  . LEU B 2 277 ? 222.986 185.195 230.979 1.00 66.45  ? 277  LEU C CA  1 
ATOM   6975 C C   . LEU B 2 277 ? 222.890 186.038 232.244 1.00 66.45  ? 277  LEU C C   1 
ATOM   6976 O O   . LEU B 2 277 ? 221.836 186.609 232.538 1.00 66.45  ? 277  LEU C O   1 
ATOM   6977 C CB  . LEU B 2 277 ? 223.120 186.095 229.750 1.00 66.45  ? 277  LEU C CB  1 
ATOM   6978 C CG  . LEU B 2 277 ? 223.071 185.377 228.400 1.00 66.45  ? 277  LEU C CG  1 
ATOM   6979 C CD1 . LEU B 2 277 ? 223.209 186.369 227.259 1.00 66.45  ? 277  LEU C CD1 1 
ATOM   6980 C CD2 . LEU B 2 277 ? 224.148 184.308 228.320 1.00 66.45  ? 277  LEU C CD2 1 
ATOM   6981 N N   . LYS B 2 278 ? 223.992 186.112 232.986 1.00 66.54  ? 278  LYS C N   1 
ATOM   6982 C CA  . LYS B 2 278 ? 224.062 186.868 234.232 1.00 66.54  ? 278  LYS C CA  1 
ATOM   6983 C C   . LYS B 2 278 ? 224.895 188.121 233.995 1.00 66.54  ? 278  LYS C C   1 
ATOM   6984 O O   . LYS B 2 278 ? 226.098 188.032 233.727 1.00 66.54  ? 278  LYS C O   1 
ATOM   6985 C CB  . LYS B 2 278 ? 224.658 186.018 235.353 1.00 66.54  ? 278  LYS C CB  1 
ATOM   6986 C CG  . LYS B 2 278 ? 224.836 186.765 236.664 1.00 66.54  ? 278  LYS C CG  1 
ATOM   6987 C CD  . LYS B 2 278 ? 225.471 185.881 237.722 1.00 66.54  ? 278  LYS C CD  1 
ATOM   6988 C CE  . LYS B 2 278 ? 225.662 186.637 239.025 1.00 66.54  ? 278  LYS C CE  1 
ATOM   6989 N NZ  . LYS B 2 278 ? 226.525 187.836 238.845 1.00 66.54  ? 278  LYS C NZ  1 
ATOM   6990 N N   . TYR B 2 279 ? 224.258 189.282 234.097 1.00 67.80  ? 279  TYR C N   1 
ATOM   6991 C CA  . TYR B 2 279 ? 224.926 190.563 233.935 1.00 67.80  ? 279  TYR C CA  1 
ATOM   6992 C C   . TYR B 2 279 ? 225.252 191.164 235.296 1.00 67.80  ? 279  TYR C C   1 
ATOM   6993 O O   . TYR B 2 279 ? 224.512 190.988 236.267 1.00 67.80  ? 279  TYR C O   1 
ATOM   6994 C CB  . TYR B 2 279 ? 224.056 191.538 233.137 1.00 67.80  ? 279  TYR C CB  1 
ATOM   6995 C CG  . TYR B 2 279 ? 223.742 191.088 231.728 1.00 67.80  ? 279  TYR C CG  1 
ATOM   6996 C CD1 . TYR B 2 279 ? 222.645 190.278 231.464 1.00 67.80  ? 279  TYR C CD1 1 
ATOM   6997 C CD2 . TYR B 2 279 ? 224.536 191.482 230.659 1.00 67.80  ? 279  TYR C CD2 1 
ATOM   6998 C CE1 . TYR B 2 279 ? 222.352 189.868 230.176 1.00 67.80  ? 279  TYR C CE1 1 
ATOM   6999 C CE2 . TYR B 2 279 ? 224.251 191.077 229.369 1.00 67.80  ? 279  TYR C CE2 1 
ATOM   7000 C CZ  . TYR B 2 279 ? 223.159 190.271 229.134 1.00 67.80  ? 279  TYR C CZ  1 
ATOM   7001 O OH  . TYR B 2 279 ? 222.872 189.866 227.851 1.00 67.80  ? 279  TYR C OH  1 
ATOM   7002 N N   . ASN B 2 280 ? 226.371 191.878 235.359 1.00 75.81  ? 280  ASN C N   1 
ATOM   7003 C CA  . ASN B 2 280 ? 226.782 192.572 236.566 1.00 75.81  ? 280  ASN C CA  1 
ATOM   7004 C C   . ASN B 2 280 ? 226.452 194.059 236.437 1.00 75.81  ? 280  ASN C C   1 
ATOM   7005 O O   . ASN B 2 280 ? 225.794 194.493 235.487 1.00 75.81  ? 280  ASN C O   1 
ATOM   7006 C CB  . ASN B 2 280 ? 228.270 192.335 236.838 1.00 75.81  ? 280  ASN C CB  1 
ATOM   7007 C CG  . ASN B 2 280 ? 229.153 192.796 235.699 1.00 75.81  ? 280  ASN C CG  1 
ATOM   7008 O OD1 . ASN B 2 280 ? 229.431 193.987 235.555 1.00 75.81  ? 280  ASN C OD1 1 
ATOM   7009 N ND2 . ASN B 2 280 ? 229.610 191.852 234.888 1.00 75.81  ? 280  ASN C ND2 1 
ATOM   7010 N N   . GLU B 2 281 ? 226.917 194.854 237.403 1.00 84.60  ? 281  GLU C N   1 
ATOM   7011 C CA  . GLU B 2 281 ? 226.592 196.275 237.447 1.00 84.60  ? 281  GLU C CA  1 
ATOM   7012 C C   . GLU B 2 281 ? 227.201 197.069 236.298 1.00 84.60  ? 281  GLU C C   1 
ATOM   7013 O O   . GLU B 2 281 ? 226.878 198.253 236.152 1.00 84.60  ? 281  GLU C O   1 
ATOM   7014 C CB  . GLU B 2 281 ? 227.048 196.872 238.779 1.00 84.60  ? 281  GLU C CB  1 
ATOM   7015 C CG  . GLU B 2 281 ? 228.541 196.745 239.036 1.00 84.60  ? 281  GLU C CG  1 
ATOM   7016 C CD  . GLU B 2 281 ? 228.958 197.349 240.362 1.00 84.60  ? 281  GLU C CD  1 
ATOM   7017 O OE1 . GLU B 2 281 ? 228.079 197.865 241.085 1.00 84.60  ? 281  GLU C OE1 1 
ATOM   7018 O OE2 . GLU B 2 281 ? 230.165 197.309 240.682 1.00 84.60  ? 281  GLU C OE2 1 
ATOM   7019 N N   . ASN B 2 282 ? 228.065 196.462 235.485 1.00 79.14  ? 282  ASN C N   1 
ATOM   7020 C CA  . ASN B 2 282 ? 228.699 197.149 234.369 1.00 79.14  ? 282  ASN C CA  1 
ATOM   7021 C C   . ASN B 2 282 ? 228.238 196.623 233.015 1.00 79.14  ? 282  ASN C C   1 
ATOM   7022 O O   . ASN B 2 282 ? 228.784 197.029 231.985 1.00 79.14  ? 282  ASN C O   1 
ATOM   7023 C CB  . ASN B 2 282 ? 230.221 197.045 234.481 1.00 79.14  ? 282  ASN C CB  1 
ATOM   7024 C CG  . ASN B 2 282 ? 230.761 197.731 235.719 1.00 79.14  ? 282  ASN C CG  1 
ATOM   7025 O OD1 . ASN B 2 282 ? 230.131 198.639 236.263 1.00 79.14  ? 282  ASN C OD1 1 
ATOM   7026 N ND2 . ASN B 2 282 ? 231.932 197.302 236.172 1.00 79.14  ? 282  ASN C ND2 1 
ATOM   7027 N N   . GLY B 2 283 ? 227.249 195.733 232.991 1.00 71.58  ? 283  GLY C N   1 
ATOM   7028 C CA  . GLY B 2 283 ? 226.746 195.211 231.738 1.00 71.58  ? 283  GLY C CA  1 
ATOM   7029 C C   . GLY B 2 283 ? 227.574 194.107 231.125 1.00 71.58  ? 283  GLY C C   1 
ATOM   7030 O O   . GLY B 2 283 ? 227.412 193.814 229.937 1.00 71.58  ? 283  GLY C O   1 
ATOM   7031 N N   . THR B 2 284 ? 228.456 193.481 231.897 1.00 69.09  ? 284  THR C N   1 
ATOM   7032 C CA  . THR B 2 284 ? 229.305 192.406 231.407 1.00 69.09  ? 284  THR C CA  1 
ATOM   7033 C C   . THR B 2 284 ? 228.787 191.066 231.916 1.00 69.09  ? 284  THR C C   1 
ATOM   7034 O O   . THR B 2 284 ? 228.437 190.930 233.091 1.00 69.09  ? 284  THR C O   1 
ATOM   7035 C CB  . THR B 2 284 ? 230.756 192.610 231.851 1.00 69.09  ? 284  THR C CB  1 
ATOM   7036 O OG1 . THR B 2 284 ? 231.209 193.902 231.428 1.00 69.09  ? 284  THR C OG1 1 
ATOM   7037 C CG2 . THR B 2 284 ? 231.659 191.544 231.247 1.00 69.09  ? 284  THR C CG2 1 
ATOM   7038 N N   . ILE B 2 285 ? 228.735 190.080 231.020 1.00 66.31  ? 285  ILE C N   1 
ATOM   7039 C CA  . ILE B 2 285 ? 228.260 188.755 231.394 1.00 66.31  ? 285  ILE C CA  1 
ATOM   7040 C C   . ILE B 2 285 ? 229.308 188.067 232.257 1.00 66.31  ? 285  ILE C C   1 
ATOM   7041 O O   . ILE B 2 285 ? 230.476 187.942 231.865 1.00 66.31  ? 285  ILE C O   1 
ATOM   7042 C CB  . ILE B 2 285 ? 227.933 187.925 230.144 1.00 66.31  ? 285  ILE C CB  1 
ATOM   7043 C CG1 . ILE B 2 285 ? 226.915 188.658 229.270 1.00 66.31  ? 285  ILE C CG1 1 
ATOM   7044 C CG2 . ILE B 2 285 ? 227.402 186.558 230.538 1.00 66.31  ? 285  ILE C CG2 1 
ATOM   7045 C CD1 . ILE B 2 285 ? 226.546 187.911 228.009 1.00 66.31  ? 285  ILE C CD1 1 
ATOM   7046 N N   . THR B 2 286 ? 228.895 187.616 233.440 1.00 69.96  ? 286  THR C N   1 
ATOM   7047 C CA  . THR B 2 286 ? 229.787 186.948 234.381 1.00 69.96  ? 286  THR C CA  1 
ATOM   7048 C C   . THR B 2 286 ? 229.639 185.432 234.350 1.00 69.96  ? 286  THR C C   1 
ATOM   7049 O O   . THR B 2 286 ? 230.641 184.713 234.284 1.00 69.96  ? 286  THR C O   1 
ATOM   7050 C CB  . THR B 2 286 ? 229.539 187.467 235.802 1.00 69.96  ? 286  THR C CB  1 
ATOM   7051 O OG1 . THR B 2 286 ? 229.734 188.886 235.836 1.00 69.96  ? 286  THR C OG1 1 
ATOM   7052 C CG2 . THR B 2 286 ? 230.493 186.807 236.786 1.00 69.96  ? 286  THR C CG2 1 
ATOM   7053 N N   . ASP B 2 287 ? 228.407 184.930 234.396 1.00 69.18  ? 287  ASP C N   1 
ATOM   7054 C CA  . ASP B 2 287 ? 228.148 183.499 234.366 1.00 69.18  ? 287  ASP C CA  1 
ATOM   7055 C C   . ASP B 2 287 ? 227.009 183.217 233.396 1.00 69.18  ? 287  ASP C C   1 
ATOM   7056 O O   . ASP B 2 287 ? 226.325 184.128 232.922 1.00 69.18  ? 287  ASP C O   1 
ATOM   7057 C CB  . ASP B 2 287 ? 227.811 182.955 235.761 1.00 69.18  ? 287  ASP C CB  1 
ATOM   7058 C CG  . ASP B 2 287 ? 228.999 182.982 236.701 1.00 69.18  ? 287  ASP C CG  1 
ATOM   7059 O OD1 . ASP B 2 287 ? 230.130 182.725 236.239 1.00 69.18  ? 287  ASP C OD1 1 
ATOM   7060 O OD2 . ASP B 2 287 ? 228.802 183.260 237.902 1.00 69.18  ? 287  ASP C OD2 1 
ATOM   7061 N N   . ALA B 2 288 ? 226.811 181.934 233.104 1.00 66.62  ? 288  ALA C N   1 
ATOM   7062 C CA  . ALA B 2 288 ? 225.742 181.503 232.217 1.00 66.62  ? 288  ALA C CA  1 
ATOM   7063 C C   . ALA B 2 288 ? 225.304 180.102 232.613 1.00 66.62  ? 288  ALA C C   1 
ATOM   7064 O O   . ALA B 2 288 ? 226.089 179.321 233.158 1.00 66.62  ? 288  ALA C O   1 
ATOM   7065 C CB  . ALA B 2 288 ? 226.177 181.532 230.748 1.00 66.62  ? 288  ALA C CB  1 
ATOM   7066 N N   . VAL B 2 289 ? 224.040 179.792 232.335 1.00 68.01  ? 289  VAL C N   1 
ATOM   7067 C CA  . VAL B 2 289 ? 223.451 178.497 232.655 1.00 68.01  ? 289  VAL C CA  1 
ATOM   7068 C C   . VAL B 2 289 ? 222.833 177.927 231.386 1.00 68.01  ? 289  VAL C C   1 
ATOM   7069 O O   . VAL B 2 289 ? 222.079 178.619 230.693 1.00 68.01  ? 289  VAL C O   1 
ATOM   7070 C CB  . VAL B 2 289 ? 222.392 178.607 233.770 1.00 68.01  ? 289  VAL C CB  1 
ATOM   7071 C CG1 . VAL B 2 289 ? 221.789 177.243 234.065 1.00 68.01  ? 289  VAL C CG1 1 
ATOM   7072 C CG2 . VAL B 2 289 ? 223.002 179.208 235.026 1.00 68.01  ? 289  VAL C CG2 1 
ATOM   7073 N N   . ASP B 2 290 ? 223.151 176.672 231.086 1.00 71.74  ? 290  ASP C N   1 
ATOM   7074 C CA  . ASP B 2 290 ? 222.634 175.988 229.909 1.00 71.74  ? 290  ASP C CA  1 
ATOM   7075 C C   . ASP B 2 290 ? 221.487 175.072 230.312 1.00 71.74  ? 290  ASP C C   1 
ATOM   7076 O O   . ASP B 2 290 ? 221.597 174.325 231.290 1.00 71.74  ? 290  ASP C O   1 
ATOM   7077 C CB  . ASP B 2 290 ? 223.737 175.185 229.217 1.00 71.74  ? 290  ASP C CB  1 
ATOM   7078 C CG  . ASP B 2 290 ? 223.219 174.367 228.052 1.00 71.74  ? 290  ASP C CG  1 
ATOM   7079 O OD1 . ASP B 2 290 ? 222.733 174.967 227.071 1.00 71.74  ? 290  ASP C OD1 1 
ATOM   7080 O OD2 . ASP B 2 290 ? 223.299 173.123 228.118 1.00 71.74  ? 290  ASP C OD2 1 
ATOM   7081 N N   . CYS B 2 291 ? 220.391 175.131 229.558 1.00 75.16  ? 291  CYS C N   1 
ATOM   7082 C CA  . CYS B 2 291 ? 219.196 174.334 229.834 1.00 75.16  ? 291  CYS C CA  1 
ATOM   7083 C C   . CYS B 2 291 ? 219.171 173.165 228.854 1.00 75.16  ? 291  CYS C C   1 
ATOM   7084 O O   . CYS B 2 291 ? 218.595 173.250 227.769 1.00 75.16  ? 291  CYS C O   1 
ATOM   7085 C CB  . CYS B 2 291 ? 217.938 175.188 229.728 1.00 75.16  ? 291  CYS C CB  1 
ATOM   7086 S SG  . CYS B 2 291 ? 217.878 176.575 230.884 1.00 75.16  ? 291  CYS C SG  1 
ATOM   7087 N N   . ALA B 2 292 ? 219.801 172.063 229.247 1.00 73.08  ? 292  ALA C N   1 
ATOM   7088 C CA  . ALA B 2 292 ? 219.840 170.863 228.420 1.00 73.08  ? 292  ALA C CA  1 
ATOM   7089 C C   . ALA B 2 292 ? 220.083 169.623 229.272 1.00 73.08  ? 292  ALA C C   1 
ATOM   7090 O O   . ALA B 2 292 ? 221.180 169.064 229.272 1.00 73.08  ? 292  ALA C O   1 
ATOM   7091 C CB  . ALA B 2 292 ? 220.912 170.990 227.350 1.00 73.08  ? 292  ALA C CB  1 
ATOM   7092 N N   . VAL C 2 320 ? 201.195 214.712 227.144 1.00 93.91  ? 320  VAL A N   1 
ATOM   7093 C CA  . VAL C 2 320 ? 200.357 214.169 226.082 1.00 93.91  ? 320  VAL A CA  1 
ATOM   7094 C C   . VAL C 2 320 ? 200.587 214.933 224.785 1.00 93.91  ? 320  VAL A C   1 
ATOM   7095 O O   . VAL C 2 320 ? 199.975 214.633 223.761 1.00 93.91  ? 320  VAL A O   1 
ATOM   7096 C CB  . VAL C 2 320 ? 198.869 214.205 226.470 1.00 93.91  ? 320  VAL A CB  1 
ATOM   7097 C CG1 . VAL C 2 320 ? 198.636 213.426 227.753 1.00 93.91  ? 320  VAL A CG1 1 
ATOM   7098 C CG2 . VAL C 2 320 ? 198.395 215.643 226.618 1.00 93.91  ? 320  VAL A CG2 1 
ATOM   7099 N N   . GLN C 2 321 ? 201.473 215.924 224.834 1.00 98.42  ? 321  GLN A N   1 
ATOM   7100 C CA  . GLN C 2 321 ? 201.727 216.770 223.677 1.00 98.42  ? 321  GLN A CA  1 
ATOM   7101 C C   . GLN C 2 321 ? 203.203 216.755 223.295 1.00 98.42  ? 321  GLN A C   1 
ATOM   7102 O O   . GLN C 2 321 ? 203.952 217.663 223.677 1.00 98.42  ? 321  GLN A O   1 
ATOM   7103 C CB  . GLN C 2 321 ? 201.261 218.202 223.953 1.00 98.42  ? 321  GLN A CB  1 
ATOM   7104 C CG  . GLN C 2 321 ? 201.140 218.551 225.432 1.00 98.42  ? 321  GLN A CG  1 
ATOM   7105 C CD  . GLN C 2 321 ? 202.482 218.632 226.135 1.00 98.42  ? 321  GLN A CD  1 
ATOM   7106 O OE1 . GLN C 2 321 ? 202.607 218.266 227.304 1.00 98.42  ? 321  GLN A OE1 1 
ATOM   7107 N NE2 . GLN C 2 321 ? 203.493 219.123 225.428 1.00 98.42  ? 321  GLN A NE2 1 
ATOM   7108 N N   . PRO C 2 322 ? 203.659 215.750 222.545 1.00 93.06  ? 322  PRO A N   1 
ATOM   7109 C CA  . PRO C 2 322 ? 205.045 215.758 222.052 1.00 93.06  ? 322  PRO A CA  1 
ATOM   7110 C C   . PRO C 2 322 ? 205.208 216.826 220.980 1.00 93.06  ? 322  PRO A C   1 
ATOM   7111 O O   . PRO C 2 322 ? 204.733 216.668 219.853 1.00 93.06  ? 322  PRO A O   1 
ATOM   7112 C CB  . PRO C 2 322 ? 205.227 214.347 221.476 1.00 93.06  ? 322  PRO A CB  1 
ATOM   7113 C CG  . PRO C 2 322 ? 204.107 213.533 222.060 1.00 93.06  ? 322  PRO A CG  1 
ATOM   7114 C CD  . PRO C 2 322 ? 202.971 214.489 222.227 1.00 93.06  ? 322  PRO A CD  1 
ATOM   7115 N N   . THR C 2 323 ? 205.884 217.917 221.335 1.00 92.03  ? 323  THR A N   1 
ATOM   7116 C CA  . THR C 2 323 ? 206.009 219.058 220.437 1.00 92.03  ? 323  THR A CA  1 
ATOM   7117 C C   . THR C 2 323 ? 207.143 218.866 219.437 1.00 92.03  ? 323  THR A C   1 
ATOM   7118 O O   . THR C 2 323 ? 206.934 218.979 218.225 1.00 92.03  ? 323  THR A O   1 
ATOM   7119 C CB  . THR C 2 323 ? 206.218 220.348 221.238 1.00 92.03  ? 323  THR A CB  1 
ATOM   7120 O OG1 . THR C 2 323 ? 206.846 221.335 220.409 1.00 92.03  ? 323  THR A OG1 1 
ATOM   7121 C CG2 . THR C 2 323 ? 207.078 220.090 222.471 1.00 92.03  ? 323  THR A CG2 1 
ATOM   7122 N N   . GLU C 2 324 ? 208.345 218.575 219.931 1.00 85.12  ? 324  GLU A N   1 
ATOM   7123 C CA  . GLU C 2 324 ? 209.513 218.451 219.069 1.00 85.12  ? 324  GLU A CA  1 
ATOM   7124 C C   . GLU C 2 324 ? 209.636 217.044 218.500 1.00 85.12  ? 324  GLU A C   1 
ATOM   7125 O O   . GLU C 2 324 ? 209.063 216.093 219.041 1.00 85.12  ? 324  GLU A O   1 
ATOM   7126 C CB  . GLU C 2 324 ? 210.779 218.824 219.841 1.00 85.12  ? 324  GLU A CB  1 
ATOM   7127 C CG  . GLU C 2 324 ? 210.813 220.268 220.307 1.00 85.12  ? 324  GLU A CG  1 
ATOM   7128 C CD  . GLU C 2 324 ? 211.793 220.487 221.439 1.00 85.12  ? 324  GLU A CD  1 
ATOM   7129 O OE1 . GLU C 2 324 ? 212.034 219.531 222.205 1.00 85.12  ? 324  GLU A OE1 1 
ATOM   7130 O OE2 . GLU C 2 324 ? 212.322 221.611 221.564 1.00 85.12  ? 324  GLU A OE2 1 
ATOM   7131 N N   . SER C 2 325 ? 210.380 216.906 217.405 1.00 76.73  ? 325  SER A N   1 
ATOM   7132 C CA  . SER C 2 325 ? 210.645 215.615 216.782 1.00 76.73  ? 325  SER A CA  1 
ATOM   7133 C C   . SER C 2 325 ? 212.110 215.574 216.380 1.00 76.73  ? 325  SER A C   1 
ATOM   7134 O O   . SER C 2 325 ? 212.502 216.204 215.393 1.00 76.73  ? 325  SER A O   1 
ATOM   7135 C CB  . SER C 2 325 ? 209.743 215.389 215.565 1.00 76.73  ? 325  SER A CB  1 
ATOM   7136 O OG  . SER C 2 325 ? 208.375 215.417 215.932 1.00 76.73  ? 325  SER A OG  1 
ATOM   7137 N N   . ILE C 2 326 ? 212.914 214.838 217.142 1.00 71.88  ? 326  ILE A N   1 
ATOM   7138 C CA  . ILE C 2 326 ? 214.351 214.770 216.919 1.00 71.88  ? 326  ILE A CA  1 
ATOM   7139 C C   . ILE C 2 326 ? 214.682 213.489 216.167 1.00 71.88  ? 326  ILE A C   1 
ATOM   7140 O O   . ILE C 2 326 ? 214.058 212.441 216.368 1.00 71.88  ? 326  ILE A O   1 
ATOM   7141 C CB  . ILE C 2 326 ? 215.142 214.850 218.242 1.00 71.88  ? 326  ILE A CB  1 
ATOM   7142 C CG1 . ILE C 2 326 ? 214.700 213.743 219.200 1.00 71.88  ? 326  ILE A CG1 1 
ATOM   7143 C CG2 . ILE C 2 326 ? 214.967 216.217 218.884 1.00 71.88  ? 326  ILE A CG2 1 
ATOM   7144 C CD1 . ILE C 2 326 ? 215.420 213.766 220.525 1.00 71.88  ? 326  ILE A CD1 1 
ATOM   7145 N N   . VAL C 2 327 ? 215.673 213.586 215.285 1.00 68.49  ? 327  VAL A N   1 
ATOM   7146 C CA  . VAL C 2 327 ? 216.155 212.458 214.497 1.00 68.49  ? 327  VAL A CA  1 
ATOM   7147 C C   . VAL C 2 327 ? 217.672 212.428 214.611 1.00 68.49  ? 327  VAL A C   1 
ATOM   7148 O O   . VAL C 2 327 ? 218.352 213.336 214.118 1.00 68.49  ? 327  VAL A O   1 
ATOM   7149 C CB  . VAL C 2 327 ? 215.725 212.554 213.023 1.00 68.49  ? 327  VAL A CB  1 
ATOM   7150 C CG1 . VAL C 2 327 ? 216.364 211.439 212.213 1.00 68.49  ? 327  VAL A CG1 1 
ATOM   7151 C CG2 . VAL C 2 327 ? 214.210 212.500 212.905 1.00 68.49  ? 327  VAL A CG2 1 
ATOM   7152 N N   . ARG C 2 328 ? 218.198 211.396 215.261 1.00 67.04  ? 328  ARG A N   1 
ATOM   7153 C CA  . ARG C 2 328 ? 219.631 211.232 215.454 1.00 67.04  ? 328  ARG A CA  1 
ATOM   7154 C C   . ARG C 2 328 ? 220.123 210.030 214.663 1.00 67.04  ? 328  ARG A C   1 
ATOM   7155 O O   . ARG C 2 328 ? 219.423 209.020 214.553 1.00 67.04  ? 328  ARG A O   1 
ATOM   7156 C CB  . ARG C 2 328 ? 219.967 211.056 216.937 1.00 67.04  ? 328  ARG A CB  1 
ATOM   7157 C CG  . ARG C 2 328 ? 219.579 212.242 217.801 1.00 67.04  ? 328  ARG A CG  1 
ATOM   7158 C CD  . ARG C 2 328 ? 220.429 213.459 217.481 1.00 67.04  ? 328  ARG A CD  1 
ATOM   7159 N NE  . ARG C 2 328 ? 221.811 213.287 217.919 1.00 67.04  ? 328  ARG A NE  1 
ATOM   7160 C CZ  . ARG C 2 328 ? 222.751 214.220 217.809 1.00 67.04  ? 328  ARG A CZ  1 
ATOM   7161 N NH1 . ARG C 2 328 ? 223.982 213.976 218.237 1.00 67.04  ? 328  ARG A NH1 1 
ATOM   7162 N NH2 . ARG C 2 328 ? 222.461 215.396 217.272 1.00 67.04  ? 328  ARG A NH2 1 
ATOM   7163 N N   . PHE C 2 329 ? 221.327 210.147 214.111 1.00 67.56  ? 329  PHE A N   1 
ATOM   7164 C CA  . PHE C 2 329 ? 221.946 209.081 213.337 1.00 67.56  ? 329  PHE A CA  1 
ATOM   7165 C C   . PHE C 2 329 ? 223.453 209.290 213.361 1.00 67.56  ? 329  PHE A C   1 
ATOM   7166 O O   . PHE C 2 329 ? 223.920 210.410 213.600 1.00 67.56  ? 329  PHE A O   1 
ATOM   7167 C CB  . PHE C 2 329 ? 221.422 209.061 211.891 1.00 67.56  ? 329  PHE A CB  1 
ATOM   7168 C CG  . PHE C 2 329 ? 220.132 208.309 211.723 1.00 67.56  ? 329  PHE A CG  1 
ATOM   7169 C CD1 . PHE C 2 329 ? 220.100 206.930 211.844 1.00 67.56  ? 329  PHE A CD1 1 
ATOM   7170 C CD2 . PHE C 2 329 ? 218.954 208.978 211.437 1.00 67.56  ? 329  PHE A CD2 1 
ATOM   7171 C CE1 . PHE C 2 329 ? 218.917 206.232 211.691 1.00 67.56  ? 329  PHE A CE1 1 
ATOM   7172 C CE2 . PHE C 2 329 ? 217.768 208.285 211.281 1.00 67.56  ? 329  PHE A CE2 1 
ATOM   7173 C CZ  . PHE C 2 329 ? 217.750 206.911 211.408 1.00 67.56  ? 329  PHE A CZ  1 
ATOM   7174 N N   . PRO C 2 330 ? 224.237 208.237 213.131 1.00 68.93  ? 330  PRO A N   1 
ATOM   7175 C CA  . PRO C 2 330 ? 225.698 208.391 213.115 1.00 68.93  ? 330  PRO A CA  1 
ATOM   7176 C C   . PRO C 2 330 ? 226.148 209.361 212.033 1.00 68.93  ? 330  PRO A C   1 
ATOM   7177 O O   . PRO C 2 330 ? 225.399 209.726 211.123 1.00 68.93  ? 330  PRO A O   1 
ATOM   7178 C CB  . PRO C 2 330 ? 226.206 206.971 212.841 1.00 68.93  ? 330  PRO A CB  1 
ATOM   7179 C CG  . PRO C 2 330 ? 225.100 206.081 213.290 1.00 68.93  ? 330  PRO A CG  1 
ATOM   7180 C CD  . PRO C 2 330 ? 223.833 206.827 212.994 1.00 68.93  ? 330  PRO A CD  1 
ATOM   7181 N N   . ASN C 2 331 ? 227.405 209.785 212.146 1.00 73.01  ? 331  ASN A N   1 
ATOM   7182 C CA  . ASN C 2 331 ? 227.966 210.719 211.180 1.00 73.01  ? 331  ASN A CA  1 
ATOM   7183 C C   . ASN C 2 331 ? 227.992 210.102 209.788 1.00 73.01  ? 331  ASN A C   1 
ATOM   7184 O O   . ASN C 2 331 ? 228.210 208.899 209.624 1.00 73.01  ? 331  ASN A O   1 
ATOM   7185 C CB  . ASN C 2 331 ? 229.378 211.134 211.596 1.00 73.01  ? 331  ASN A CB  1 
ATOM   7186 C CG  . ASN C 2 331 ? 229.380 212.153 212.716 1.00 73.01  ? 331  ASN A CG  1 
ATOM   7187 O OD1 . ASN C 2 331 ? 228.351 212.752 213.026 1.00 73.01  ? 331  ASN A OD1 1 
ATOM   7188 N ND2 . ASN C 2 331 ? 230.542 212.362 213.327 1.00 73.01  ? 331  ASN A ND2 1 
ATOM   7189 N N   . ILE C 2 332 ? 227.765 210.940 208.778 1.00 69.93  ? 332  ILE A N   1 
ATOM   7190 C CA  . ILE C 2 332 ? 227.755 210.490 207.392 1.00 69.93  ? 332  ILE A CA  1 
ATOM   7191 C C   . ILE C 2 332 ? 229.193 210.393 206.902 1.00 69.93  ? 332  ILE A C   1 
ATOM   7192 O O   . ILE C 2 332 ? 229.774 211.381 206.440 1.00 69.93  ? 332  ILE A O   1 
ATOM   7193 C CB  . ILE C 2 332 ? 226.922 211.427 206.496 1.00 69.93  ? 332  ILE A CB  1 
ATOM   7194 C CG1 . ILE C 2 332 ? 225.482 211.529 207.006 1.00 69.93  ? 332  ILE A CG1 1 
ATOM   7195 C CG2 . ILE C 2 332 ? 226.932 210.936 205.056 1.00 69.93  ? 332  ILE A CG2 1 
ATOM   7196 C CD1 . ILE C 2 332 ? 225.227 212.709 207.923 1.00 69.93  ? 332  ILE A CD1 1 
ATOM   7197 N N   . THR C 2 333 ? 229.777 209.205 207.011 1.00 67.53  ? 333  THR A N   1 
ATOM   7198 C CA  . THR C 2 333 ? 231.141 208.948 206.578 1.00 67.53  ? 333  THR A CA  1 
ATOM   7199 C C   . THR C 2 333 ? 231.136 207.922 205.453 1.00 67.53  ? 333  THR A C   1 
ATOM   7200 O O   . THR C 2 333 ? 230.125 207.270 205.178 1.00 67.53  ? 333  THR A O   1 
ATOM   7201 C CB  . THR C 2 333 ? 232.011 208.455 207.742 1.00 67.53  ? 333  THR A CB  1 
ATOM   7202 O OG1 . THR C 2 333 ? 231.464 207.241 208.270 1.00 67.53  ? 333  THR A OG1 1 
ATOM   7203 C CG2 . THR C 2 333 ? 232.068 209.501 208.844 1.00 67.53  ? 333  THR A CG2 1 
ATOM   7204 N N   . ASN C 2 334 ? 232.292 207.789 204.801 1.00 67.36  ? 334  ASN A N   1 
ATOM   7205 C CA  . ASN C 2 334 ? 232.483 206.860 203.688 1.00 67.36  ? 334  ASN A CA  1 
ATOM   7206 C C   . ASN C 2 334 ? 231.491 207.150 202.559 1.00 67.36  ? 334  ASN A C   1 
ATOM   7207 O O   . ASN C 2 334 ? 230.633 206.335 202.215 1.00 67.36  ? 334  ASN A O   1 
ATOM   7208 C CB  . ASN C 2 334 ? 232.380 205.406 204.163 1.00 67.36  ? 334  ASN A CB  1 
ATOM   7209 C CG  . ASN C 2 334 ? 232.764 204.411 203.086 1.00 67.36  ? 334  ASN A CG  1 
ATOM   7210 O OD1 . ASN C 2 334 ? 233.475 204.747 202.139 1.00 67.36  ? 334  ASN A OD1 1 
ATOM   7211 N ND2 . ASN C 2 334 ? 232.294 203.177 203.226 1.00 67.36  ? 334  ASN A ND2 1 
ATOM   7212 N N   . LEU C 2 335 ? 231.619 208.347 201.993 1.00 66.05  ? 335  LEU A N   1 
ATOM   7213 C CA  . LEU C 2 335 ? 230.787 208.731 200.862 1.00 66.05  ? 335  LEU A CA  1 
ATOM   7214 C C   . LEU C 2 335 ? 231.162 207.919 199.628 1.00 66.05  ? 335  LEU A C   1 
ATOM   7215 O O   . LEU C 2 335 ? 232.313 207.513 199.448 1.00 66.05  ? 335  LEU A O   1 
ATOM   7216 C CB  . LEU C 2 335 ? 230.932 210.225 200.567 1.00 66.05  ? 335  LEU A CB  1 
ATOM   7217 C CG  . LEU C 2 335 ? 230.251 211.233 201.500 1.00 66.05  ? 335  LEU A CG  1 
ATOM   7218 C CD1 . LEU C 2 335 ? 228.799 210.846 201.746 1.00 66.05  ? 335  LEU A CD1 1 
ATOM   7219 C CD2 . LEU C 2 335 ? 231.004 211.397 202.814 1.00 66.05  ? 335  LEU A CD2 1 
ATOM   7220 N N   . CYS C 2 336 ? 230.172 207.681 198.774 1.00 67.67  ? 336  CYS A N   1 
ATOM   7221 C CA  . CYS C 2 336 ? 230.420 206.924 197.558 1.00 67.67  ? 336  CYS A CA  1 
ATOM   7222 C C   . CYS C 2 336 ? 231.294 207.736 196.605 1.00 67.67  ? 336  CYS A C   1 
ATOM   7223 O O   . CYS C 2 336 ? 231.136 208.957 196.502 1.00 67.67  ? 336  CYS A O   1 
ATOM   7224 C CB  . CYS C 2 336 ? 229.105 206.553 196.873 1.00 67.67  ? 336  CYS A CB  1 
ATOM   7225 S SG  . CYS C 2 336 ? 228.054 205.433 197.824 1.00 67.67  ? 336  CYS A SG  1 
ATOM   7226 N N   . PRO C 2 337 ? 232.226 207.093 195.900 1.00 66.94  ? 337  PRO A N   1 
ATOM   7227 C CA  . PRO C 2 337 ? 233.118 207.839 195.003 1.00 66.94  ? 337  PRO A CA  1 
ATOM   7228 C C   . PRO C 2 337 ? 232.418 208.328 193.745 1.00 66.94  ? 337  PRO A C   1 
ATOM   7229 O O   . PRO C 2 337 ? 232.744 207.892 192.636 1.00 66.94  ? 337  PRO A O   1 
ATOM   7230 C CB  . PRO C 2 337 ? 234.212 206.817 194.674 1.00 66.94  ? 337  PRO A CB  1 
ATOM   7231 C CG  . PRO C 2 337 ? 233.529 205.498 194.801 1.00 66.94  ? 337  PRO A CG  1 
ATOM   7232 C CD  . PRO C 2 337 ? 232.538 205.653 195.923 1.00 66.94  ? 337  PRO A CD  1 
ATOM   7233 N N   . PHE C 2 338 ? 231.451 209.235 193.905 1.00 65.18  ? 338  PHE A N   1 
ATOM   7234 C CA  . PHE C 2 338 ? 230.787 209.812 192.742 1.00 65.18  ? 338  PHE A CA  1 
ATOM   7235 C C   . PHE C 2 338 ? 231.689 210.800 192.015 1.00 65.18  ? 338  PHE A C   1 
ATOM   7236 O O   . PHE C 2 338 ? 231.635 210.892 190.783 1.00 65.18  ? 338  PHE A O   1 
ATOM   7237 C CB  . PHE C 2 338 ? 229.483 210.491 193.159 1.00 65.18  ? 338  PHE A CB  1 
ATOM   7238 C CG  . PHE C 2 338 ? 228.342 209.537 193.361 1.00 65.18  ? 338  PHE A CG  1 
ATOM   7239 C CD1 . PHE C 2 338 ? 228.340 208.298 192.742 1.00 65.18  ? 338  PHE A CD1 1 
ATOM   7240 C CD2 . PHE C 2 338 ? 227.269 209.881 194.165 1.00 65.18  ? 338  PHE A CD2 1 
ATOM   7241 C CE1 . PHE C 2 338 ? 227.291 207.419 192.924 1.00 65.18  ? 338  PHE A CE1 1 
ATOM   7242 C CE2 . PHE C 2 338 ? 226.217 209.006 194.351 1.00 65.18  ? 338  PHE A CE2 1 
ATOM   7243 C CZ  . PHE C 2 338 ? 226.228 207.773 193.729 1.00 65.18  ? 338  PHE A CZ  1 
ATOM   7244 N N   . GLY C 2 339 ? 232.517 211.543 192.752 1.00 65.62  ? 339  GLY A N   1 
ATOM   7245 C CA  . GLY C 2 339 ? 233.438 212.474 192.124 1.00 65.62  ? 339  GLY A CA  1 
ATOM   7246 C C   . GLY C 2 339 ? 234.517 211.809 191.299 1.00 65.62  ? 339  GLY A C   1 
ATOM   7247 O O   . GLY C 2 339 ? 235.175 212.481 190.499 1.00 65.62  ? 339  GLY A O   1 
ATOM   7248 N N   . GLU C 2 340 ? 234.717 210.502 191.475 1.00 67.13  ? 340  GLU A N   1 
ATOM   7249 C CA  . GLU C 2 340 ? 235.703 209.783 190.679 1.00 67.13  ? 340  GLU A CA  1 
ATOM   7250 C C   . GLU C 2 340 ? 235.180 209.457 189.286 1.00 67.13  ? 340  GLU A C   1 
ATOM   7251 O O   . GLU C 2 340 ? 235.960 209.428 188.328 1.00 67.13  ? 340  GLU A O   1 
ATOM   7252 C CB  . GLU C 2 340 ? 236.121 208.500 191.401 1.00 67.13  ? 340  GLU A CB  1 
ATOM   7253 C CG  . GLU C 2 340 ? 237.217 207.714 190.701 1.00 67.13  ? 340  GLU A CG  1 
ATOM   7254 C CD  . GLU C 2 340 ? 237.598 206.454 191.451 1.00 67.13  ? 340  GLU A CD  1 
ATOM   7255 O OE1 . GLU C 2 340 ? 237.014 206.202 192.526 1.00 67.13  ? 340  GLU A OE1 1 
ATOM   7256 O OE2 . GLU C 2 340 ? 238.480 205.715 190.967 1.00 67.13  ? 340  GLU A OE2 1 
ATOM   7257 N N   . VAL C 2 341 ? 233.876 209.222 189.151 1.00 64.18  ? 341  VAL A N   1 
ATOM   7258 C CA  . VAL C 2 341 ? 233.289 208.852 187.869 1.00 64.18  ? 341  VAL A CA  1 
ATOM   7259 C C   . VAL C 2 341 ? 232.726 210.094 187.187 1.00 64.18  ? 341  VAL A C   1 
ATOM   7260 O O   . VAL C 2 341 ? 232.642 210.155 185.955 1.00 64.18  ? 341  VAL A O   1 
ATOM   7261 C CB  . VAL C 2 341 ? 232.211 207.763 188.047 1.00 64.18  ? 341  VAL A CB  1 
ATOM   7262 C CG1 . VAL C 2 341 ? 231.045 208.282 188.875 1.00 64.18  ? 341  VAL A CG1 1 
ATOM   7263 C CG2 . VAL C 2 341 ? 231.736 207.243 186.697 1.00 64.18  ? 341  VAL A CG2 1 
ATOM   7264 N N   . PHE C 2 342 ? 232.351 211.101 187.978 1.00 63.24  ? 342  PHE A N   1 
ATOM   7265 C CA  . PHE C 2 342 ? 231.813 212.336 187.419 1.00 63.24  ? 342  PHE A CA  1 
ATOM   7266 C C   . PHE C 2 342 ? 232.906 213.320 187.020 1.00 63.24  ? 342  PHE A C   1 
ATOM   7267 O O   . PHE C 2 342 ? 232.807 213.958 185.966 1.00 63.24  ? 342  PHE A O   1 
ATOM   7268 C CB  . PHE C 2 342 ? 230.857 212.995 188.417 1.00 63.24  ? 342  PHE A CB  1 
ATOM   7269 C CG  . PHE C 2 342 ? 229.459 212.447 188.370 1.00 63.24  ? 342  PHE A CG  1 
ATOM   7270 C CD1 . PHE C 2 342 ? 229.121 211.310 189.084 1.00 63.24  ? 342  PHE A CD1 1 
ATOM   7271 C CD2 . PHE C 2 342 ? 228.483 213.070 187.613 1.00 63.24  ? 342  PHE A CD2 1 
ATOM   7272 C CE1 . PHE C 2 342 ? 227.837 210.804 189.043 1.00 63.24  ? 342  PHE A CE1 1 
ATOM   7273 C CE2 . PHE C 2 342 ? 227.196 212.570 187.569 1.00 63.24  ? 342  PHE A CE2 1 
ATOM   7274 C CZ  . PHE C 2 342 ? 226.873 211.436 188.285 1.00 63.24  ? 342  PHE A CZ  1 
ATOM   7275 N N   . ASN C 2 343 ? 233.949 213.460 187.840 1.00 68.19  ? 343  ASN A N   1 
ATOM   7276 C CA  . ASN C 2 343 ? 235.080 214.326 187.531 1.00 68.19  ? 343  ASN A CA  1 
ATOM   7277 C C   . ASN C 2 343 ? 236.272 213.546 186.986 1.00 68.19  ? 343  ASN A C   1 
ATOM   7278 O O   . ASN C 2 343 ? 237.423 213.918 187.235 1.00 68.19  ? 343  ASN A O   1 
ATOM   7279 C CB  . ASN C 2 343 ? 235.493 215.130 188.764 1.00 68.19  ? 343  ASN A CB  1 
ATOM   7280 C CG  . ASN C 2 343 ? 234.637 216.363 188.972 1.00 68.19  ? 343  ASN A CG  1 
ATOM   7281 O OD1 . ASN C 2 343 ? 234.712 217.319 188.201 1.00 68.19  ? 343  ASN A OD1 1 
ATOM   7282 N ND2 . ASN C 2 343 ? 233.823 216.352 190.022 1.00 68.19  ? 343  ASN A ND2 1 
ATOM   7283 N N   . ALA C 2 344 ? 236.017 212.468 186.249 1.00 65.09  ? 344  ALA A N   1 
ATOM   7284 C CA  . ALA C 2 344 ? 237.100 211.689 185.669 1.00 65.09  ? 344  ALA A CA  1 
ATOM   7285 C C   . ALA C 2 344 ? 237.763 212.462 184.536 1.00 65.09  ? 344  ALA A C   1 
ATOM   7286 O O   . ALA C 2 344 ? 237.094 213.122 183.736 1.00 65.09  ? 344  ALA A O   1 
ATOM   7287 C CB  . ALA C 2 344 ? 236.578 210.347 185.157 1.00 65.09  ? 344  ALA A CB  1 
ATOM   7288 N N   . THR C 2 345 ? 239.093 212.380 184.474 1.00 66.04  ? 345  THR A N   1 
ATOM   7289 C CA  . THR C 2 345 ? 239.831 213.111 183.450 1.00 66.04  ? 345  THR A CA  1 
ATOM   7290 C C   . THR C 2 345 ? 239.620 212.495 182.072 1.00 66.04  ? 345  THR A C   1 
ATOM   7291 O O   . THR C 2 345 ? 239.311 213.201 181.105 1.00 66.04  ? 345  THR A O   1 
ATOM   7292 C CB  . THR C 2 345 ? 241.319 213.149 183.800 1.00 66.04  ? 345  THR A CB  1 
ATOM   7293 O OG1 . THR C 2 345 ? 241.498 213.797 185.066 1.00 66.04  ? 345  THR A OG1 1 
ATOM   7294 C CG2 . THR C 2 345 ? 242.097 213.906 182.735 1.00 66.04  ? 345  THR A CG2 1 
ATOM   7295 N N   . ARG C 2 346 ? 239.779 211.179 181.963 1.00 68.30  ? 346  ARG A N   1 
ATOM   7296 C CA  . ARG C 2 346 ? 239.677 210.474 180.691 1.00 68.30  ? 346  ARG A CA  1 
ATOM   7297 C C   . ARG C 2 346 ? 238.490 209.524 180.738 1.00 68.30  ? 346  ARG A C   1 
ATOM   7298 O O   . ARG C 2 346 ? 238.470 208.589 181.545 1.00 68.30  ? 346  ARG A O   1 
ATOM   7299 C CB  . ARG C 2 346 ? 240.967 209.710 180.384 1.00 68.30  ? 346  ARG A CB  1 
ATOM   7300 C CG  . ARG C 2 346 ? 240.939 208.950 179.069 1.00 68.30  ? 346  ARG A CG  1 
ATOM   7301 C CD  . ARG C 2 346 ? 242.256 208.233 178.821 1.00 68.30  ? 346  ARG A CD  1 
ATOM   7302 N NE  . ARG C 2 346 ? 242.567 207.281 179.883 1.00 68.30  ? 346  ARG A NE  1 
ATOM   7303 C CZ  . ARG C 2 346 ? 243.660 206.526 179.912 1.00 68.30  ? 346  ARG A CZ  1 
ATOM   7304 N NH1 . ARG C 2 346 ? 243.862 205.685 180.918 1.00 68.30  ? 346  ARG A NH1 1 
ATOM   7305 N NH2 . ARG C 2 346 ? 244.553 206.610 178.935 1.00 68.30  ? 346  ARG A NH2 1 
ATOM   7306 N N   . PHE C 2 347 ? 237.509 209.764 179.876 1.00 60.17  ? 347  PHE A N   1 
ATOM   7307 C CA  . PHE C 2 347 ? 236.358 208.889 179.724 1.00 60.17  ? 347  PHE A CA  1 
ATOM   7308 C C   . PHE C 2 347 ? 236.588 207.909 178.579 1.00 60.17  ? 347  PHE A C   1 
ATOM   7309 O O   . PHE C 2 347 ? 237.464 208.099 177.732 1.00 60.17  ? 347  PHE A O   1 
ATOM   7310 C CB  . PHE C 2 347 ? 235.085 209.700 179.472 1.00 60.17  ? 347  PHE A CB  1 
ATOM   7311 C CG  . PHE C 2 347 ? 234.455 210.249 180.720 1.00 60.17  ? 347  PHE A CG  1 
ATOM   7312 C CD1 . PHE C 2 347 ? 235.043 211.298 181.406 1.00 60.17  ? 347  PHE A CD1 1 
ATOM   7313 C CD2 . PHE C 2 347 ? 233.269 209.721 181.201 1.00 60.17  ? 347  PHE A CD2 1 
ATOM   7314 C CE1 . PHE C 2 347 ? 234.462 211.804 182.553 1.00 60.17  ? 347  PHE A CE1 1 
ATOM   7315 C CE2 . PHE C 2 347 ? 232.684 210.224 182.347 1.00 60.17  ? 347  PHE A CE2 1 
ATOM   7316 C CZ  . PHE C 2 347 ? 233.281 211.267 183.023 1.00 60.17  ? 347  PHE A CZ  1 
ATOM   7317 N N   . ALA C 2 348 ? 235.784 206.853 178.564 1.00 56.47  ? 348  ALA A N   1 
ATOM   7318 C CA  . ALA C 2 348 ? 235.886 205.812 177.554 1.00 56.47  ? 348  ALA A CA  1 
ATOM   7319 C C   . ALA C 2 348 ? 234.858 206.032 176.450 1.00 56.47  ? 348  ALA A C   1 
ATOM   7320 O O   . ALA C 2 348 ? 233.932 206.837 176.572 1.00 56.47  ? 348  ALA A O   1 
ATOM   7321 C CB  . ALA C 2 348 ? 235.703 204.429 178.185 1.00 56.47  ? 348  ALA A CB  1 
ATOM   7322 N N   . SER C 2 349 ? 235.037 205.297 175.357 1.00 57.00  ? 349  SER A N   1 
ATOM   7323 C CA  . SER C 2 349 ? 234.112 205.376 174.240 1.00 57.00  ? 349  SER A CA  1 
ATOM   7324 C C   . SER C 2 349 ? 232.797 204.682 174.591 1.00 57.00  ? 349  SER A C   1 
ATOM   7325 O O   . SER C 2 349 ? 232.653 204.045 175.638 1.00 57.00  ? 349  SER A O   1 
ATOM   7326 C CB  . SER C 2 349 ? 234.731 204.754 172.990 1.00 57.00  ? 349  SER A CB  1 
ATOM   7327 O OG  . SER C 2 349 ? 235.944 205.400 172.646 1.00 57.00  ? 349  SER A OG  1 
ATOM   7328 N N   . VAL C 2 350 ? 231.823 204.812 173.689 1.00 57.77  ? 350  VAL A N   1 
ATOM   7329 C CA  . VAL C 2 350 ? 230.510 204.233 173.946 1.00 57.77  ? 350  VAL A CA  1 
ATOM   7330 C C   . VAL C 2 350 ? 230.530 202.717 173.763 1.00 57.77  ? 350  VAL A C   1 
ATOM   7331 O O   . VAL C 2 350 ? 229.735 202.004 174.385 1.00 57.77  ? 350  VAL A O   1 
ATOM   7332 C CB  . VAL C 2 350 ? 229.450 204.902 173.053 1.00 57.77  ? 350  VAL A CB  1 
ATOM   7333 C CG1 . VAL C 2 350 ? 229.707 204.591 171.590 1.00 57.77  ? 350  VAL A CG1 1 
ATOM   7334 C CG2 . VAL C 2 350 ? 228.048 204.474 173.463 1.00 57.77  ? 350  VAL A CG2 1 
ATOM   7335 N N   . TYR C 2 351 ? 231.432 202.194 172.929 1.00 56.00  ? 351  TYR A N   1 
ATOM   7336 C CA  . TYR C 2 351 ? 231.514 200.752 172.739 1.00 56.00  ? 351  TYR A CA  1 
ATOM   7337 C C   . TYR C 2 351 ? 232.307 200.062 173.840 1.00 56.00  ? 351  TYR A C   1 
ATOM   7338 O O   . TYR C 2 351 ? 232.120 198.862 174.062 1.00 56.00  ? 351  TYR A O   1 
ATOM   7339 C CB  . TYR C 2 351 ? 232.132 200.428 171.375 1.00 56.00  ? 351  TYR A CB  1 
ATOM   7340 C CG  . TYR C 2 351 ? 233.641 200.517 171.332 1.00 56.00  ? 351  TYR A CG  1 
ATOM   7341 C CD1 . TYR C 2 351 ? 234.281 201.740 171.190 1.00 56.00  ? 351  TYR A CD1 1 
ATOM   7342 C CD2 . TYR C 2 351 ? 234.426 199.374 171.420 1.00 56.00  ? 351  TYR A CD2 1 
ATOM   7343 C CE1 . TYR C 2 351 ? 235.660 201.824 171.146 1.00 56.00  ? 351  TYR A CE1 1 
ATOM   7344 C CE2 . TYR C 2 351 ? 235.805 199.448 171.378 1.00 56.00  ? 351  TYR A CE2 1 
ATOM   7345 C CZ  . TYR C 2 351 ? 236.416 200.675 171.241 1.00 56.00  ? 351  TYR A CZ  1 
ATOM   7346 O OH  . TYR C 2 351 ? 237.789 200.753 171.198 1.00 56.00  ? 351  TYR A OH  1 
ATOM   7347 N N   . ALA C 2 352 ? 233.183 200.791 174.532 1.00 56.64  ? 352  ALA A N   1 
ATOM   7348 C CA  . ALA C 2 352 ? 233.975 200.222 175.614 1.00 56.64  ? 352  ALA A CA  1 
ATOM   7349 C C   . ALA C 2 352 ? 233.698 200.955 176.920 1.00 56.64  ? 352  ALA A C   1 
ATOM   7350 O O   . ALA C 2 352 ? 234.628 201.309 177.651 1.00 56.64  ? 352  ALA A O   1 
ATOM   7351 C CB  . ALA C 2 352 ? 235.466 200.275 175.276 1.00 56.64  ? 352  ALA A CB  1 
ATOM   7352 N N   . TRP C 2 353 ? 232.421 201.192 177.211 1.00 56.21  ? 353  TRP A N   1 
ATOM   7353 C CA  . TRP C 2 353 ? 232.045 201.928 178.411 1.00 56.21  ? 353  TRP A CA  1 
ATOM   7354 C C   . TRP C 2 353 ? 232.454 201.171 179.668 1.00 56.21  ? 353  TRP A C   1 
ATOM   7355 O O   . TRP C 2 353 ? 232.288 199.952 179.763 1.00 56.21  ? 353  TRP A O   1 
ATOM   7356 C CB  . TRP C 2 353 ? 230.537 202.185 178.418 1.00 56.21  ? 353  TRP A CB  1 
ATOM   7357 C CG  . TRP C 2 353 ? 229.713 200.955 178.164 1.00 56.21  ? 353  TRP A CG  1 
ATOM   7358 C CD1 . TRP C 2 353 ? 229.332 200.461 176.951 1.00 56.21  ? 353  TRP A CD1 1 
ATOM   7359 C CD2 . TRP C 2 353 ? 229.165 200.069 179.147 1.00 56.21  ? 353  TRP A CD2 1 
ATOM   7360 N NE1 . TRP C 2 353 ? 228.583 199.322 177.116 1.00 56.21  ? 353  TRP A NE1 1 
ATOM   7361 C CE2 . TRP C 2 353 ? 228.466 199.059 178.456 1.00 56.21  ? 353  TRP A CE2 1 
ATOM   7362 C CE3 . TRP C 2 353 ? 229.198 200.029 180.544 1.00 56.21  ? 353  TRP A CE3 1 
ATOM   7363 C CZ2 . TRP C 2 353 ? 227.806 198.024 179.113 1.00 56.21  ? 353  TRP A CZ2 1 
ATOM   7364 C CZ3 . TRP C 2 353 ? 228.543 199.000 181.194 1.00 56.21  ? 353  TRP A CZ3 1 
ATOM   7365 C CH2 . TRP C 2 353 ? 227.856 198.012 180.479 1.00 56.21  ? 353  TRP A CH2 1 
ATOM   7366 N N   . ASN C 2 354 ? 232.995 201.904 180.636 1.00 56.79  ? 354  ASN A N   1 
ATOM   7367 C CA  . ASN C 2 354 ? 233.366 201.316 181.913 1.00 56.79  ? 354  ASN A CA  1 
ATOM   7368 C C   . ASN C 2 354 ? 232.132 201.102 182.779 1.00 56.79  ? 354  ASN A C   1 
ATOM   7369 O O   . ASN C 2 354 ? 231.136 201.823 182.671 1.00 56.79  ? 354  ASN A O   1 
ATOM   7370 C CB  . ASN C 2 354 ? 234.367 202.205 182.653 1.00 56.79  ? 354  ASN A CB  1 
ATOM   7371 C CG  . ASN C 2 354 ? 235.673 202.360 181.904 1.00 56.79  ? 354  ASN A CG  1 
ATOM   7372 O OD1 . ASN C 2 354 ? 236.484 201.436 181.849 1.00 56.79  ? 354  ASN A OD1 1 
ATOM   7373 N ND2 . ASN C 2 354 ? 235.890 203.538 181.333 1.00 56.79  ? 354  ASN A ND2 1 
ATOM   7374 N N   . ARG C 2 355 ? 232.208 200.096 183.649 1.00 57.09  ? 355  ARG A N   1 
ATOM   7375 C CA  . ARG C 2 355 ? 231.117 199.741 184.556 1.00 57.09  ? 355  ARG A CA  1 
ATOM   7376 C C   . ARG C 2 355 ? 231.695 199.675 185.966 1.00 57.09  ? 355  ARG A C   1 
ATOM   7377 O O   . ARG C 2 355 ? 232.111 198.609 186.428 1.00 57.09  ? 355  ARG A O   1 
ATOM   7378 C CB  . ARG C 2 355 ? 230.468 198.424 184.145 1.00 57.09  ? 355  ARG A CB  1 
ATOM   7379 C CG  . ARG C 2 355 ? 229.196 198.089 184.904 1.00 57.09  ? 355  ARG A CG  1 
ATOM   7380 C CD  . ARG C 2 355 ? 228.613 196.767 184.433 1.00 57.09  ? 355  ARG A CD  1 
ATOM   7381 N NE  . ARG C 2 355 ? 227.316 196.492 185.042 1.00 57.09  ? 355  ARG A NE  1 
ATOM   7382 C CZ  . ARG C 2 355 ? 226.153 196.864 184.517 1.00 57.09  ? 355  ARG A CZ  1 
ATOM   7383 N NH1 . ARG C 2 355 ? 225.019 196.571 185.137 1.00 57.09  ? 355  ARG A NH1 1 
ATOM   7384 N NH2 . ARG C 2 355 ? 226.124 197.530 183.371 1.00 57.09  ? 355  ARG A NH2 1 
ATOM   7385 N N   . LYS C 2 356 ? 231.723 200.818 186.645 1.00 57.73  ? 356  LYS A N   1 
ATOM   7386 C CA  . LYS C 2 356 ? 232.227 200.873 188.008 1.00 57.73  ? 356  LYS A CA  1 
ATOM   7387 C C   . LYS C 2 356 ? 231.136 200.467 188.990 1.00 57.73  ? 356  LYS A C   1 
ATOM   7388 O O   . LYS C 2 356 ? 229.982 200.888 188.869 1.00 57.73  ? 356  LYS A O   1 
ATOM   7389 C CB  . LYS C 2 356 ? 232.736 202.276 188.336 1.00 57.73  ? 356  LYS A CB  1 
ATOM   7390 C CG  . LYS C 2 356 ? 233.369 202.399 189.712 1.00 57.73  ? 356  LYS A CG  1 
ATOM   7391 C CD  . LYS C 2 356 ? 233.900 203.800 189.954 1.00 57.73  ? 356  LYS A CD  1 
ATOM   7392 C CE  . LYS C 2 356 ? 234.548 203.912 191.323 1.00 57.73  ? 356  LYS A CE  1 
ATOM   7393 N NZ  . LYS C 2 356 ? 235.680 202.959 191.478 1.00 57.73  ? 356  LYS A NZ  1 
ATOM   7394 N N   . ARG C 2 357 ? 231.508 199.642 189.964 1.00 61.10  ? 357  ARG A N   1 
ATOM   7395 C CA  . ARG C 2 357 ? 230.566 199.141 190.953 1.00 61.10  ? 357  ARG A CA  1 
ATOM   7396 C C   . ARG C 2 357 ? 230.604 200.022 192.195 1.00 61.10  ? 357  ARG A C   1 
ATOM   7397 O O   . ARG C 2 357 ? 231.681 200.330 192.714 1.00 61.10  ? 357  ARG A O   1 
ATOM   7398 C CB  . ARG C 2 357 ? 230.888 197.692 191.317 1.00 61.10  ? 357  ARG A CB  1 
ATOM   7399 C CG  . ARG C 2 357 ? 229.838 197.029 192.188 1.00 61.10  ? 357  ARG A CG  1 
ATOM   7400 C CD  . ARG C 2 357 ? 230.168 195.569 192.433 1.00 61.10  ? 357  ARG A CD  1 
ATOM   7401 N NE  . ARG C 2 357 ? 229.113 194.898 193.186 1.00 61.10  ? 357  ARG A NE  1 
ATOM   7402 C CZ  . ARG C 2 357 ? 229.051 194.864 194.512 1.00 61.10  ? 357  ARG A CZ  1 
ATOM   7403 N NH1 . ARG C 2 357 ? 228.055 194.230 195.115 1.00 61.10  ? 357  ARG A NH1 1 
ATOM   7404 N NH2 . ARG C 2 357 ? 229.988 195.460 195.237 1.00 61.10  ? 357  ARG A NH2 1 
ATOM   7405 N N   . ILE C 2 358 ? 229.427 200.425 192.664 1.00 61.55  ? 358  ILE A N   1 
ATOM   7406 C CA  . ILE C 2 358 ? 229.286 201.286 193.833 1.00 61.55  ? 358  ILE A CA  1 
ATOM   7407 C C   . ILE C 2 358 ? 228.537 200.506 194.902 1.00 61.55  ? 358  ILE A C   1 
ATOM   7408 O O   . ILE C 2 358 ? 227.376 200.126 194.702 1.00 61.55  ? 358  ILE A O   1 
ATOM   7409 C CB  . ILE C 2 358 ? 228.556 202.594 193.493 1.00 61.55  ? 358  ILE A CB  1 
ATOM   7410 C CG1 . ILE C 2 358 ? 229.342 203.388 192.448 1.00 61.55  ? 358  ILE A CG1 1 
ATOM   7411 C CG2 . ILE C 2 358 ? 228.340 203.425 194.745 1.00 61.55  ? 358  ILE A CG2 1 
ATOM   7412 C CD1 . ILE C 2 358 ? 230.729 203.785 192.901 1.00 61.55  ? 358  ILE A CD1 1 
ATOM   7413 N N   . SER C 2 359 ? 229.196 200.269 196.034 1.00 64.16  ? 359  SER A N   1 
ATOM   7414 C CA  . SER C 2 359 ? 228.584 199.532 197.130 1.00 64.16  ? 359  SER A CA  1 
ATOM   7415 C C   . SER C 2 359 ? 229.325 199.854 198.419 1.00 64.16  ? 359  SER A C   1 
ATOM   7416 O O   . SER C 2 359 ? 230.449 200.363 198.400 1.00 64.16  ? 359  SER A O   1 
ATOM   7417 C CB  . SER C 2 359 ? 228.592 198.022 196.867 1.00 64.16  ? 359  SER A CB  1 
ATOM   7418 O OG  . SER C 2 359 ? 228.002 197.314 197.943 1.00 64.16  ? 359  SER A OG  1 
ATOM   7419 N N   . ASN C 2 360 ? 228.670 199.547 199.541 1.00 66.16  ? 360  ASN A N   1 
ATOM   7420 C CA  . ASN C 2 360 ? 229.230 199.753 200.878 1.00 66.16  ? 360  ASN A CA  1 
ATOM   7421 C C   . ASN C 2 360 ? 229.618 201.215 201.099 1.00 66.16  ? 360  ASN A C   1 
ATOM   7422 O O   . ASN C 2 360 ? 230.733 201.532 201.518 1.00 66.16  ? 360  ASN A O   1 
ATOM   7423 C CB  . ASN C 2 360 ? 230.421 198.824 201.124 1.00 66.16  ? 360  ASN A CB  1 
ATOM   7424 C CG  . ASN C 2 360 ? 230.047 197.360 201.023 1.00 66.16  ? 360  ASN A CG  1 
ATOM   7425 O OD1 . ASN C 2 360 ? 230.153 196.752 199.959 1.00 66.16  ? 360  ASN A OD1 1 
ATOM   7426 N ND2 . ASN C 2 360 ? 229.604 196.784 202.135 1.00 66.16  ? 360  ASN A ND2 1 
ATOM   7427 N N   . CYS C 2 361 ? 228.676 202.112 200.817 1.00 66.21  ? 361  CYS A N   1 
ATOM   7428 C CA  . CYS C 2 361 ? 228.900 203.541 200.984 1.00 66.21  ? 361  CYS A CA  1 
ATOM   7429 C C   . CYS C 2 361 ? 227.556 204.253 200.958 1.00 66.21  ? 361  CYS A C   1 
ATOM   7430 O O   . CYS C 2 361 ? 226.558 203.716 200.471 1.00 66.21  ? 361  CYS A O   1 
ATOM   7431 C CB  . CYS C 2 361 ? 229.828 204.097 199.897 1.00 66.21  ? 361  CYS A CB  1 
ATOM   7432 S SG  . CYS C 2 361 ? 229.240 203.829 198.208 1.00 66.21  ? 361  CYS A SG  1 
ATOM   7433 N N   . VAL C 2 362 ? 227.546 205.471 201.489 1.00 65.72  ? 362  VAL A N   1 
ATOM   7434 C CA  . VAL C 2 362 ? 226.355 206.312 201.481 1.00 65.72  ? 362  VAL A CA  1 
ATOM   7435 C C   . VAL C 2 362 ? 226.424 207.230 200.267 1.00 65.72  ? 362  VAL A C   1 
ATOM   7436 O O   . VAL C 2 362 ? 227.392 207.979 200.095 1.00 65.72  ? 362  VAL A O   1 
ATOM   7437 C CB  . VAL C 2 362 ? 226.227 207.115 202.784 1.00 65.72  ? 362  VAL A CB  1 
ATOM   7438 C CG1 . VAL C 2 362 ? 225.652 206.240 203.886 1.00 65.72  ? 362  VAL A CG1 1 
ATOM   7439 C CG2 . VAL C 2 362 ? 227.577 207.669 203.206 1.00 65.72  ? 362  VAL A CG2 1 
ATOM   7440 N N   . ALA C 2 363 ? 225.403 207.163 199.418 1.00 65.66  ? 363  ALA A N   1 
ATOM   7441 C CA  . ALA C 2 363 ? 225.368 207.909 198.165 1.00 65.66  ? 363  ALA A CA  1 
ATOM   7442 C C   . ALA C 2 363 ? 224.485 209.137 198.345 1.00 65.66  ? 363  ALA A C   1 
ATOM   7443 O O   . ALA C 2 363 ? 223.264 209.018 198.490 1.00 65.66  ? 363  ALA A O   1 
ATOM   7444 C CB  . ALA C 2 363 ? 224.860 207.028 197.026 1.00 65.66  ? 363  ALA A CB  1 
ATOM   7445 N N   . ASP C 2 364 ? 225.103 210.316 198.330 1.00 67.68  ? 364  ASP A N   1 
ATOM   7446 C CA  . ASP C 2 364 ? 224.380 211.580 198.452 1.00 67.68  ? 364  ASP A CA  1 
ATOM   7447 C C   . ASP C 2 364 ? 223.999 212.039 197.050 1.00 67.68  ? 364  ASP A C   1 
ATOM   7448 O O   . ASP C 2 364 ? 224.801 212.657 196.346 1.00 67.68  ? 364  ASP A O   1 
ATOM   7449 C CB  . ASP C 2 364 ? 225.230 212.619 199.174 1.00 67.68  ? 364  ASP A CB  1 
ATOM   7450 C CG  . ASP C 2 364 ? 224.411 213.786 199.695 1.00 67.68  ? 364  ASP A CG  1 
ATOM   7451 O OD1 . ASP C 2 364 ? 223.334 214.067 199.129 1.00 67.68  ? 364  ASP A OD1 1 
ATOM   7452 O OD2 . ASP C 2 364 ? 224.847 214.425 200.676 1.00 67.68  ? 364  ASP A OD2 1 
ATOM   7453 N N   . TYR C 2 365 ? 222.768 211.734 196.641 1.00 65.39  ? 365  TYR A N   1 
ATOM   7454 C CA  . TYR C 2 365 ? 222.289 212.127 195.323 1.00 65.39  ? 365  TYR A CA  1 
ATOM   7455 C C   . TYR C 2 365 ? 221.819 213.575 195.270 1.00 65.39  ? 365  TYR A C   1 
ATOM   7456 O O   . TYR C 2 365 ? 221.477 214.056 194.185 1.00 65.39  ? 365  TYR A O   1 
ATOM   7457 C CB  . TYR C 2 365 ? 221.151 211.205 194.879 1.00 65.39  ? 365  TYR A CB  1 
ATOM   7458 C CG  . TYR C 2 365 ? 221.524 209.741 194.848 1.00 65.39  ? 365  TYR A CG  1 
ATOM   7459 C CD1 . TYR C 2 365 ? 222.272 209.217 193.802 1.00 65.39  ? 365  TYR A CD1 1 
ATOM   7460 C CD2 . TYR C 2 365 ? 221.123 208.881 195.862 1.00 65.39  ? 365  TYR A CD2 1 
ATOM   7461 C CE1 . TYR C 2 365 ? 222.614 207.879 193.769 1.00 65.39  ? 365  TYR A CE1 1 
ATOM   7462 C CE2 . TYR C 2 365 ? 221.460 207.542 195.837 1.00 65.39  ? 365  TYR A CE2 1 
ATOM   7463 C CZ  . TYR C 2 365 ? 222.205 207.046 194.788 1.00 65.39  ? 365  TYR A CZ  1 
ATOM   7464 O OH  . TYR C 2 365 ? 222.543 205.713 194.759 1.00 65.39  ? 365  TYR A OH  1 
ATOM   7465 N N   . SER C 2 366 ? 221.795 214.276 196.406 1.00 68.46  ? 366  SER A N   1 
ATOM   7466 C CA  . SER C 2 366 ? 221.362 215.669 196.402 1.00 68.46  ? 366  SER A CA  1 
ATOM   7467 C C   . SER C 2 366 ? 222.380 216.572 195.720 1.00 68.46  ? 366  SER A C   1 
ATOM   7468 O O   . SER C 2 366 ? 222.002 217.583 195.117 1.00 68.46  ? 366  SER A O   1 
ATOM   7469 C CB  . SER C 2 366 ? 221.105 216.144 197.832 1.00 68.46  ? 366  SER A CB  1 
ATOM   7470 O OG  . SER C 2 366 ? 220.081 215.381 198.446 1.00 68.46  ? 366  SER A OG  1 
ATOM   7471 N N   . VAL C 2 367 ? 223.668 216.229 195.800 1.00 66.97  ? 367  VAL A N   1 
ATOM   7472 C CA  . VAL C 2 367 ? 224.690 217.037 195.147 1.00 66.97  ? 367  VAL A CA  1 
ATOM   7473 C C   . VAL C 2 367 ? 224.647 216.869 193.633 1.00 66.97  ? 367  VAL A C   1 
ATOM   7474 O O   . VAL C 2 367 ? 225.090 217.760 192.900 1.00 66.97  ? 367  VAL A O   1 
ATOM   7475 C CB  . VAL C 2 367 ? 226.083 216.688 195.710 1.00 66.97  ? 367  VAL A CB  1 
ATOM   7476 C CG1 . VAL C 2 367 ? 226.506 215.290 195.282 1.00 66.97  ? 367  VAL A CG1 1 
ATOM   7477 C CG2 . VAL C 2 367 ? 227.115 217.728 195.291 1.00 66.97  ? 367  VAL A CG2 1 
ATOM   7478 N N   . LEU C 2 368 ? 224.105 215.753 193.141 1.00 65.28  ? 368  LEU A N   1 
ATOM   7479 C CA  . LEU C 2 368 ? 223.998 215.549 191.701 1.00 65.28  ? 368  LEU A CA  1 
ATOM   7480 C C   . LEU C 2 368 ? 222.792 216.276 191.121 1.00 65.28  ? 368  LEU A C   1 
ATOM   7481 O O   . LEU C 2 368 ? 222.892 216.895 190.055 1.00 65.28  ? 368  LEU A O   1 
ATOM   7482 C CB  . LEU C 2 368 ? 223.919 214.055 191.386 1.00 65.28  ? 368  LEU A CB  1 
ATOM   7483 C CG  . LEU C 2 368 ? 225.119 213.204 191.803 1.00 65.28  ? 368  LEU A CG  1 
ATOM   7484 C CD1 . LEU C 2 368 ? 224.890 211.745 191.443 1.00 65.28  ? 368  LEU A CD1 1 
ATOM   7485 C CD2 . LEU C 2 368 ? 226.392 213.724 191.158 1.00 65.28  ? 368  LEU A CD2 1 
ATOM   7486 N N   . TYR C 2 369 ? 221.648 216.212 191.804 1.00 69.39  ? 369  TYR A N   1 
ATOM   7487 C CA  . TYR C 2 369 ? 220.450 216.874 191.298 1.00 69.39  ? 369  TYR A CA  1 
ATOM   7488 C C   . TYR C 2 369 ? 220.554 218.387 191.441 1.00 69.39  ? 369  TYR A C   1 
ATOM   7489 O O   . TYR C 2 369 ? 220.126 219.131 190.551 1.00 69.39  ? 369  TYR A O   1 
ATOM   7490 C CB  . TYR C 2 369 ? 219.214 216.347 192.027 1.00 69.39  ? 369  TYR A CB  1 
ATOM   7491 C CG  . TYR C 2 369 ? 217.910 216.599 191.301 1.00 69.39  ? 369  TYR A CG  1 
ATOM   7492 C CD1 . TYR C 2 369 ? 217.897 217.020 189.978 1.00 69.39  ? 369  TYR A CD1 1 
ATOM   7493 C CD2 . TYR C 2 369 ? 216.692 216.421 191.943 1.00 69.39  ? 369  TYR A CD2 1 
ATOM   7494 C CE1 . TYR C 2 369 ? 216.708 217.252 189.313 1.00 69.39  ? 369  TYR A CE1 1 
ATOM   7495 C CE2 . TYR C 2 369 ? 215.498 216.651 191.286 1.00 69.39  ? 369  TYR A CE2 1 
ATOM   7496 C CZ  . TYR C 2 369 ? 215.512 217.066 189.972 1.00 69.39  ? 369  TYR A CZ  1 
ATOM   7497 O OH  . TYR C 2 369 ? 214.326 217.297 189.314 1.00 69.39  ? 369  TYR A OH  1 
ATOM   7498 N N   . ASN C 2 370 ? 221.122 218.861 192.548 1.00 68.95  ? 370  ASN A N   1 
ATOM   7499 C CA  . ASN C 2 370 ? 221.276 220.296 192.787 1.00 68.95  ? 370  ASN A CA  1 
ATOM   7500 C C   . ASN C 2 370 ? 222.572 220.807 192.152 1.00 68.95  ? 370  ASN A C   1 
ATOM   7501 O O   . ASN C 2 370 ? 223.469 221.329 192.812 1.00 68.95  ? 370  ASN A O   1 
ATOM   7502 C CB  . ASN C 2 370 ? 221.233 220.590 194.281 1.00 68.95  ? 370  ASN A CB  1 
ATOM   7503 C CG  . ASN C 2 370 ? 219.963 220.087 194.937 1.00 68.95  ? 370  ASN A CG  1 
ATOM   7504 O OD1 . ASN C 2 370 ? 218.915 219.996 194.297 1.00 68.95  ? 370  ASN A OD1 1 
ATOM   7505 N ND2 . ASN C 2 370 ? 220.049 219.758 196.220 1.00 68.95  ? 370  ASN A ND2 1 
ATOM   7506 N N   . SER C 2 371 ? 222.651 220.640 190.834 1.00 63.72  ? 371  SER A N   1 
ATOM   7507 C CA  . SER C 2 371 ? 223.808 221.090 190.066 1.00 63.72  ? 371  SER A CA  1 
ATOM   7508 C C   . SER C 2 371 ? 223.340 221.360 188.643 1.00 63.72  ? 371  SER A C   1 
ATOM   7509 O O   . SER C 2 371 ? 222.969 220.427 187.925 1.00 63.72  ? 371  SER A O   1 
ATOM   7510 C CB  . SER C 2 371 ? 224.926 220.052 190.092 1.00 63.72  ? 371  SER A CB  1 
ATOM   7511 O OG  . SER C 2 371 ? 226.055 220.500 189.362 1.00 63.72  ? 371  SER A OG  1 
ATOM   7512 N N   . ALA C 2 372 ? 223.358 222.629 188.240 1.00 62.27  ? 372  ALA A N   1 
ATOM   7513 C CA  . ALA C 2 372 ? 222.884 223.027 186.921 1.00 62.27  ? 372  ALA A CA  1 
ATOM   7514 C C   . ALA C 2 372 ? 223.854 222.674 185.802 1.00 62.27  ? 372  ALA A C   1 
ATOM   7515 O O   . ALA C 2 372 ? 223.585 223.014 184.645 1.00 62.27  ? 372  ALA A O   1 
ATOM   7516 C CB  . ALA C 2 372 ? 222.600 224.532 186.897 1.00 62.27  ? 372  ALA A CB  1 
ATOM   7517 N N   . SER C 2 373 ? 224.966 222.004 186.110 1.00 58.45  ? 373  SER A N   1 
ATOM   7518 C CA  . SER C 2 373 ? 225.926 221.640 185.075 1.00 58.45  ? 373  SER A CA  1 
ATOM   7519 C C   . SER C 2 373 ? 225.424 220.509 184.188 1.00 58.45  ? 373  SER A C   1 
ATOM   7520 O O   . SER C 2 373 ? 225.892 220.375 183.053 1.00 58.45  ? 373  SER A O   1 
ATOM   7521 C CB  . SER C 2 373 ? 227.260 221.247 185.711 1.00 58.45  ? 373  SER A CB  1 
ATOM   7522 O OG  . SER C 2 373 ? 227.791 222.311 186.482 1.00 58.45  ? 373  SER A OG  1 
ATOM   7523 N N   . PHE C 2 374 ? 224.485 219.701 184.673 1.00 56.78  ? 374  PHE A N   1 
ATOM   7524 C CA  . PHE C 2 374 ? 223.976 218.564 183.919 1.00 56.78  ? 374  PHE A CA  1 
ATOM   7525 C C   . PHE C 2 374 ? 222.767 218.986 183.094 1.00 56.78  ? 374  PHE A C   1 
ATOM   7526 O O   . PHE C 2 374 ? 221.832 219.600 183.618 1.00 56.78  ? 374  PHE A O   1 
ATOM   7527 C CB  . PHE C 2 374 ? 223.605 217.418 184.859 1.00 56.78  ? 374  PHE A CB  1 
ATOM   7528 C CG  . PHE C 2 374 ? 224.680 217.079 185.852 1.00 56.78  ? 374  PHE A CG  1 
ATOM   7529 C CD1 . PHE C 2 374 ? 225.862 216.490 185.439 1.00 56.78  ? 374  PHE A CD1 1 
ATOM   7530 C CD2 . PHE C 2 374 ? 224.506 217.348 187.199 1.00 56.78  ? 374  PHE A CD2 1 
ATOM   7531 C CE1 . PHE C 2 374 ? 226.852 216.177 186.350 1.00 56.78  ? 374  PHE A CE1 1 
ATOM   7532 C CE2 . PHE C 2 374 ? 225.492 217.037 188.115 1.00 56.78  ? 374  PHE A CE2 1 
ATOM   7533 C CZ  . PHE C 2 374 ? 226.666 216.450 187.690 1.00 56.78  ? 374  PHE A CZ  1 
ATOM   7534 N N   . SER C 2 375 ? 222.789 218.651 181.803 1.00 56.60  ? 375  SER A N   1 
ATOM   7535 C CA  . SER C 2 375 ? 221.694 219.030 180.917 1.00 56.60  ? 375  SER A CA  1 
ATOM   7536 C C   . SER C 2 375 ? 220.495 218.104 181.075 1.00 56.60  ? 375  SER A C   1 
ATOM   7537 O O   . SER C 2 375 ? 219.353 218.572 181.149 1.00 56.60  ? 375  SER A O   1 
ATOM   7538 C CB  . SER C 2 375 ? 222.172 219.039 179.465 1.00 56.60  ? 375  SER A CB  1 
ATOM   7539 O OG  . SER C 2 375 ? 222.625 217.756 179.069 1.00 56.60  ? 375  SER A OG  1 
ATOM   7540 N N   . THR C 2 376 ? 220.728 216.795 181.129 1.00 58.17  ? 376  THR A N   1 
ATOM   7541 C CA  . THR C 2 376 ? 219.665 215.809 181.256 1.00 58.17  ? 376  THR A CA  1 
ATOM   7542 C C   . THR C 2 376 ? 219.843 215.037 182.554 1.00 58.17  ? 376  THR A C   1 
ATOM   7543 O O   . THR C 2 376 ? 220.919 214.487 182.812 1.00 58.17  ? 376  THR A O   1 
ATOM   7544 C CB  . THR C 2 376 ? 219.657 214.843 180.067 1.00 58.17  ? 376  THR A CB  1 
ATOM   7545 O OG1 . THR C 2 376 ? 220.891 214.116 180.031 1.00 58.17  ? 376  THR A OG1 1 
ATOM   7546 C CG2 . THR C 2 376 ? 219.485 215.604 178.762 1.00 58.17  ? 376  THR A CG2 1 
ATOM   7547 N N   . PHE C 2 377 ? 218.790 214.998 183.365 1.00 60.41  ? 377  PHE A N   1 
ATOM   7548 C CA  . PHE C 2 377 ? 218.773 214.279 184.634 1.00 60.41  ? 377  PHE A CA  1 
ATOM   7549 C C   . PHE C 2 377 ? 217.498 213.453 184.747 1.00 60.41  ? 377  PHE A C   1 
ATOM   7550 O O   . PHE C 2 377 ? 216.795 213.473 185.759 1.00 60.41  ? 377  PHE A O   1 
ATOM   7551 C CB  . PHE C 2 377 ? 218.905 215.244 185.809 1.00 60.41  ? 377  PHE A CB  1 
ATOM   7552 C CG  . PHE C 2 377 ? 219.598 214.655 187.006 1.00 60.41  ? 377  PHE A CG  1 
ATOM   7553 C CD1 . PHE C 2 377 ? 218.906 213.867 187.911 1.00 60.41  ? 377  PHE A CD1 1 
ATOM   7554 C CD2 . PHE C 2 377 ? 220.943 214.896 187.229 1.00 60.41  ? 377  PHE A CD2 1 
ATOM   7555 C CE1 . PHE C 2 377 ? 219.543 213.327 189.011 1.00 60.41  ? 377  PHE A CE1 1 
ATOM   7556 C CE2 . PHE C 2 377 ? 221.585 214.360 188.328 1.00 60.41  ? 377  PHE A CE2 1 
ATOM   7557 C CZ  . PHE C 2 377 ? 220.884 213.574 189.220 1.00 60.41  ? 377  PHE A CZ  1 
ATOM   7558 N N   . LYS C 2 378 ? 217.179 212.720 183.685 1.00 61.77  ? 378  LYS A N   1 
ATOM   7559 C CA  . LYS C 2 378 ? 215.966 211.915 183.655 1.00 61.77  ? 378  LYS A CA  1 
ATOM   7560 C C   . LYS C 2 378 ? 216.155 210.646 184.475 1.00 61.77  ? 378  LYS A C   1 
ATOM   7561 O O   . LYS C 2 378 ? 217.184 209.972 184.368 1.00 61.77  ? 378  LYS A O   1 
ATOM   7562 C CB  . LYS C 2 378 ? 215.594 211.569 182.214 1.00 61.77  ? 378  LYS A CB  1 
ATOM   7563 C CG  . LYS C 2 378 ? 215.292 212.781 181.348 1.00 61.77  ? 378  LYS A CG  1 
ATOM   7564 C CD  . LYS C 2 378 ? 214.949 212.377 179.925 1.00 61.77  ? 378  LYS A CD  1 
ATOM   7565 C CE  . LYS C 2 378 ? 216.119 211.682 179.251 1.00 61.77  ? 378  LYS A CE  1 
ATOM   7566 N NZ  . LYS C 2 378 ? 217.318 212.561 179.175 1.00 61.77  ? 378  LYS A NZ  1 
ATOM   7567 N N   . CYS C 2 379 ? 215.160 210.324 185.298 1.00 65.62  ? 379  CYS A N   1 
ATOM   7568 C CA  . CYS C 2 379 ? 215.165 209.121 186.118 1.00 65.62  ? 379  CYS A CA  1 
ATOM   7569 C C   . CYS C 2 379 ? 214.012 208.226 185.690 1.00 65.62  ? 379  CYS A C   1 
ATOM   7570 O O   . CYS C 2 379 ? 212.878 208.694 185.548 1.00 65.62  ? 379  CYS A O   1 
ATOM   7571 C CB  . CYS C 2 379 ? 215.050 209.463 187.605 1.00 65.62  ? 379  CYS A CB  1 
ATOM   7572 S SG  . CYS C 2 379 ? 216.487 210.308 188.304 1.00 65.62  ? 379  CYS A SG  1 
ATOM   7573 N N   . TYR C 2 380 ? 214.304 206.946 185.486 1.00 62.06  ? 380  TYR A N   1 
ATOM   7574 C CA  . TYR C 2 380 ? 213.317 205.972 185.043 1.00 62.06  ? 380  TYR A CA  1 
ATOM   7575 C C   . TYR C 2 380 ? 213.060 204.966 186.155 1.00 62.06  ? 380  TYR A C   1 
ATOM   7576 O O   . TYR C 2 380 ? 214.000 204.360 186.680 1.00 62.06  ? 380  TYR A O   1 
ATOM   7577 C CB  . TYR C 2 380 ? 213.788 205.257 183.775 1.00 62.06  ? 380  TYR A CB  1 
ATOM   7578 C CG  . TYR C 2 380 ? 214.031 206.189 182.610 1.00 62.06  ? 380  TYR A CG  1 
ATOM   7579 C CD1 . TYR C 2 380 ? 213.000 206.535 181.748 1.00 62.06  ? 380  TYR A CD1 1 
ATOM   7580 C CD2 . TYR C 2 380 ? 215.290 206.725 182.375 1.00 62.06  ? 380  TYR A CD2 1 
ATOM   7581 C CE1 . TYR C 2 380 ? 213.216 207.387 180.683 1.00 62.06  ? 380  TYR A CE1 1 
ATOM   7582 C CE2 . TYR C 2 380 ? 215.515 207.578 181.313 1.00 62.06  ? 380  TYR A CE2 1 
ATOM   7583 C CZ  . TYR C 2 380 ? 214.475 207.905 180.470 1.00 62.06  ? 380  TYR A CZ  1 
ATOM   7584 O OH  . TYR C 2 380 ? 214.692 208.754 179.410 1.00 62.06  ? 380  TYR A OH  1 
ATOM   7585 N N   . GLY C 2 381 ? 211.789 204.794 186.511 1.00 64.42  ? 381  GLY A N   1 
ATOM   7586 C CA  . GLY C 2 381 ? 211.411 203.860 187.550 1.00 64.42  ? 381  GLY A CA  1 
ATOM   7587 C C   . GLY C 2 381 ? 211.697 204.311 188.963 1.00 64.42  ? 381  GLY A C   1 
ATOM   7588 O O   . GLY C 2 381 ? 211.512 203.521 189.896 1.00 64.42  ? 381  GLY A O   1 
ATOM   7589 N N   . VAL C 2 382 ? 212.139 205.554 189.156 1.00 64.31  ? 382  VAL A N   1 
ATOM   7590 C CA  . VAL C 2 382 ? 212.442 206.066 190.486 1.00 64.31  ? 382  VAL A CA  1 
ATOM   7591 C C   . VAL C 2 382 ? 212.359 207.584 190.430 1.00 64.31  ? 382  VAL A C   1 
ATOM   7592 O O   . VAL C 2 382 ? 212.555 208.191 189.374 1.00 64.31  ? 382  VAL A O   1 
ATOM   7593 C CB  . VAL C 2 382 ? 213.831 205.575 190.972 1.00 64.31  ? 382  VAL A CB  1 
ATOM   7594 C CG1 . VAL C 2 382 ? 214.949 206.255 190.195 1.00 64.31  ? 382  VAL A CG1 1 
ATOM   7595 C CG2 . VAL C 2 382 ? 213.989 205.790 192.472 1.00 64.31  ? 382  VAL A CG2 1 
ATOM   7596 N N   . SER C 2 383 ? 212.052 208.197 191.572 1.00 64.64  ? 383  SER A N   1 
ATOM   7597 C CA  . SER C 2 383 ? 211.940 209.649 191.626 1.00 64.64  ? 383  SER A CA  1 
ATOM   7598 C C   . SER C 2 383 ? 213.262 210.268 192.075 1.00 64.64  ? 383  SER A C   1 
ATOM   7599 O O   . SER C 2 383 ? 213.934 209.723 192.956 1.00 64.64  ? 383  SER A O   1 
ATOM   7600 C CB  . SER C 2 383 ? 210.829 210.070 192.582 1.00 64.64  ? 383  SER A CB  1 
ATOM   7601 O OG  . SER C 2 383 ? 210.697 211.480 192.624 1.00 64.64  ? 383  SER A OG  1 
ATOM   7602 N N   . PRO C 2 384 ? 213.650 211.400 191.482 1.00 67.29  ? 384  PRO A N   1 
ATOM   7603 C CA  . PRO C 2 384 ? 214.936 212.012 191.856 1.00 67.29  ? 384  PRO A CA  1 
ATOM   7604 C C   . PRO C 2 384 ? 214.969 212.525 193.284 1.00 67.29  ? 384  PRO A C   1 
ATOM   7605 O O   . PRO C 2 384 ? 216.034 212.496 193.914 1.00 67.29  ? 384  PRO A O   1 
ATOM   7606 C CB  . PRO C 2 384 ? 215.090 213.156 190.843 1.00 67.29  ? 384  PRO A CB  1 
ATOM   7607 C CG  . PRO C 2 384 ? 214.159 212.813 189.719 1.00 67.29  ? 384  PRO A CG  1 
ATOM   7608 C CD  . PRO C 2 384 ? 213.010 212.101 190.358 1.00 67.29  ? 384  PRO A CD  1 
ATOM   7609 N N   . THR C 2 385 ? 213.841 213.000 193.815 1.00 65.74  ? 385  THR A N   1 
ATOM   7610 C CA  . THR C 2 385 ? 213.832 213.522 195.178 1.00 65.74  ? 385  THR A CA  1 
ATOM   7611 C C   . THR C 2 385 ? 213.922 212.398 196.203 1.00 65.74  ? 385  THR A C   1 
ATOM   7612 O O   . THR C 2 385 ? 214.564 212.554 197.249 1.00 65.74  ? 385  THR A O   1 
ATOM   7613 C CB  . THR C 2 385 ? 212.576 214.360 195.413 1.00 65.74  ? 385  THR A CB  1 
ATOM   7614 O OG1 . THR C 2 385 ? 211.412 213.546 195.219 1.00 65.74  ? 385  THR A OG1 1 
ATOM   7615 C CG2 . THR C 2 385 ? 212.532 215.534 194.447 1.00 65.74  ? 385  THR A CG2 1 
ATOM   7616 N N   . LYS C 2 386 ? 213.287 211.260 195.925 1.00 66.23  ? 386  LYS A N   1 
ATOM   7617 C CA  . LYS C 2 386 ? 213.269 210.127 196.840 1.00 66.23  ? 386  LYS A CA  1 
ATOM   7618 C C   . LYS C 2 386 ? 214.482 209.216 196.679 1.00 66.23  ? 386  LYS A C   1 
ATOM   7619 O O   . LYS C 2 386 ? 214.459 208.080 197.166 1.00 66.23  ? 386  LYS A O   1 
ATOM   7620 C CB  . LYS C 2 386 ? 211.981 209.322 196.656 1.00 66.23  ? 386  LYS A CB  1 
ATOM   7621 C CG  . LYS C 2 386 ? 210.712 210.111 196.927 1.00 66.23  ? 386  LYS A CG  1 
ATOM   7622 C CD  . LYS C 2 386 ? 209.486 209.213 196.895 1.00 66.23  ? 386  LYS A CD  1 
ATOM   7623 C CE  . LYS C 2 386 ? 209.349 208.510 195.556 1.00 66.23  ? 386  LYS A CE  1 
ATOM   7624 N NZ  . LYS C 2 386 ? 208.152 207.625 195.513 1.00 66.23  ? 386  LYS A NZ  1 
ATOM   7625 N N   . LEU C 2 387 ? 215.536 209.684 196.007 1.00 66.67  ? 387  LEU A N   1 
ATOM   7626 C CA  . LEU C 2 387 ? 216.731 208.861 195.847 1.00 66.67  ? 387  LEU A CA  1 
ATOM   7627 C C   . LEU C 2 387 ? 217.462 208.680 197.171 1.00 66.67  ? 387  LEU A C   1 
ATOM   7628 O O   . LEU C 2 387 ? 217.981 207.594 197.456 1.00 66.67  ? 387  LEU A O   1 
ATOM   7629 C CB  . LEU C 2 387 ? 217.661 209.479 194.802 1.00 66.67  ? 387  LEU A CB  1 
ATOM   7630 C CG  . LEU C 2 387 ? 217.187 209.431 193.349 1.00 66.67  ? 387  LEU A CG  1 
ATOM   7631 C CD1 . LEU C 2 387 ? 218.194 210.110 192.435 1.00 66.67  ? 387  LEU A CD1 1 
ATOM   7632 C CD2 . LEU C 2 387 ? 216.949 207.995 192.914 1.00 66.67  ? 387  LEU A CD2 1 
ATOM   7633 N N   . ASN C 2 388 ? 217.514 209.727 197.992 1.00 68.52  ? 388  ASN A N   1 
ATOM   7634 C CA  . ASN C 2 388 ? 218.206 209.667 199.273 1.00 68.52  ? 388  ASN A CA  1 
ATOM   7635 C C   . ASN C 2 388 ? 217.403 208.955 200.354 1.00 68.52  ? 388  ASN A C   1 
ATOM   7636 O O   . ASN C 2 388 ? 217.878 208.861 201.491 1.00 68.52  ? 388  ASN A O   1 
ATOM   7637 C CB  . ASN C 2 388 ? 218.560 211.079 199.746 1.00 68.52  ? 388  ASN A CB  1 
ATOM   7638 C CG  . ASN C 2 388 ? 219.524 211.781 198.812 1.00 68.52  ? 388  ASN A CG  1 
ATOM   7639 O OD1 . ASN C 2 388 ? 220.337 211.142 198.145 1.00 68.52  ? 388  ASN A OD1 1 
ATOM   7640 N ND2 . ASN C 2 388 ? 219.440 213.105 198.761 1.00 68.52  ? 388  ASN A ND2 1 
ATOM   7641 N N   . ASP C 2 389 ? 216.208 208.456 200.035 1.00 68.56  ? 389  ASP A N   1 
ATOM   7642 C CA  . ASP C 2 389 ? 215.372 207.755 201.003 1.00 68.56  ? 389  ASP A CA  1 
ATOM   7643 C C   . ASP C 2 389 ? 215.174 206.290 200.633 1.00 68.56  ? 389  ASP A C   1 
ATOM   7644 O O   . ASP C 2 389 ? 214.204 205.667 201.077 1.00 68.56  ? 389  ASP A O   1 
ATOM   7645 C CB  . ASP C 2 389 ? 214.018 208.454 201.144 1.00 68.56  ? 389  ASP A CB  1 
ATOM   7646 C CG  . ASP C 2 389 ? 214.151 209.892 201.602 1.00 68.56  ? 389  ASP A CG  1 
ATOM   7647 O OD1 . ASP C 2 389 ? 215.117 210.198 202.331 1.00 68.56  ? 389  ASP A OD1 1 
ATOM   7648 O OD2 . ASP C 2 389 ? 213.289 210.717 201.232 1.00 68.56  ? 389  ASP A OD2 1 
ATOM   7649 N N   . LEU C 2 390 ? 216.074 205.724 199.832 1.00 67.03  ? 390  LEU A N   1 
ATOM   7650 C CA  . LEU C 2 390 ? 215.977 204.339 199.401 1.00 67.03  ? 390  LEU A CA  1 
ATOM   7651 C C   . LEU C 2 390 ? 217.331 203.660 199.538 1.00 67.03  ? 390  LEU A C   1 
ATOM   7652 O O   . LEU C 2 390 ? 218.381 204.299 199.426 1.00 67.03  ? 390  LEU A O   1 
ATOM   7653 C CB  . LEU C 2 390 ? 215.488 204.233 197.950 1.00 67.03  ? 390  LEU A CB  1 
ATOM   7654 C CG  . LEU C 2 390 ? 214.083 204.763 197.655 1.00 67.03  ? 390  LEU A CG  1 
ATOM   7655 C CD1 . LEU C 2 390 ? 213.776 204.665 196.170 1.00 67.03  ? 390  LEU A CD1 1 
ATOM   7656 C CD2 . LEU C 2 390 ? 213.045 204.009 198.471 1.00 67.03  ? 390  LEU A CD2 1 
ATOM   7657 N N   . CYS C 2 391 ? 217.295 202.354 199.782 1.00 69.57  ? 391  CYS A N   1 
ATOM   7658 C CA  . CYS C 2 391 ? 218.490 201.534 199.900 1.00 69.57  ? 391  CYS A CA  1 
ATOM   7659 C C   . CYS C 2 391 ? 218.571 200.558 198.734 1.00 69.57  ? 391  CYS A C   1 
ATOM   7660 O O   . CYS C 2 391 ? 217.551 200.143 198.176 1.00 69.57  ? 391  CYS A O   1 
ATOM   7661 C CB  . CYS C 2 391 ? 218.502 200.757 201.219 1.00 69.57  ? 391  CYS A CB  1 
ATOM   7662 S SG  . CYS C 2 391 ? 218.806 201.736 202.709 1.00 69.57  ? 391  CYS A SG  1 
ATOM   7663 N N   . PHE C 2 392 ? 219.798 200.192 198.372 1.00 63.68  ? 392  PHE A N   1 
ATOM   7664 C CA  . PHE C 2 392 ? 220.043 199.240 197.300 1.00 63.68  ? 392  PHE A CA  1 
ATOM   7665 C C   . PHE C 2 392 ? 221.225 198.361 197.680 1.00 63.68  ? 392  PHE A C   1 
ATOM   7666 O O   . PHE C 2 392 ? 221.922 198.609 198.667 1.00 63.68  ? 392  PHE A O   1 
ATOM   7667 C CB  . PHE C 2 392 ? 220.303 199.947 195.963 1.00 63.68  ? 392  PHE A CB  1 
ATOM   7668 C CG  . PHE C 2 392 ? 219.157 200.795 195.492 1.00 63.68  ? 392  PHE A CG  1 
ATOM   7669 C CD1 . PHE C 2 392 ? 218.104 200.232 194.790 1.00 63.68  ? 392  PHE A CD1 1 
ATOM   7670 C CD2 . PHE C 2 392 ? 219.134 202.156 195.748 1.00 63.68  ? 392  PHE A CD2 1 
ATOM   7671 C CE1 . PHE C 2 392 ? 217.049 201.010 194.355 1.00 63.68  ? 392  PHE A CE1 1 
ATOM   7672 C CE2 . PHE C 2 392 ? 218.081 202.939 195.315 1.00 63.68  ? 392  PHE A CE2 1 
ATOM   7673 C CZ  . PHE C 2 392 ? 217.038 202.365 194.618 1.00 63.68  ? 392  PHE A CZ  1 
ATOM   7674 N N   . THR C 2 393 ? 221.446 197.317 196.881 1.00 65.23  ? 393  THR A N   1 
ATOM   7675 C CA  . THR C 2 393 ? 222.564 196.411 197.109 1.00 65.23  ? 393  THR A CA  1 
ATOM   7676 C C   . THR C 2 393 ? 223.841 196.891 196.431 1.00 65.23  ? 393  THR A C   1 
ATOM   7677 O O   . THR C 2 393 ? 224.919 196.838 197.033 1.00 65.23  ? 393  THR A O   1 
ATOM   7678 C CB  . THR C 2 393 ? 222.216 195.003 196.617 1.00 65.23  ? 393  THR A CB  1 
ATOM   7679 O OG1 . THR C 2 393 ? 221.926 195.043 195.215 1.00 65.23  ? 393  THR A OG1 1 
ATOM   7680 C CG2 . THR C 2 393 ? 221.008 194.463 197.365 1.00 65.23  ? 393  THR A CG2 1 
ATOM   7681 N N   . ASN C 2 394 ? 223.739 197.363 195.191 1.00 62.83  ? 394  ASN A N   1 
ATOM   7682 C CA  . ASN C 2 394 ? 224.895 197.853 194.456 1.00 62.83  ? 394  ASN A CA  1 
ATOM   7683 C C   . ASN C 2 394 ? 224.412 198.710 193.296 1.00 62.83  ? 394  ASN A C   1 
ATOM   7684 O O   . ASN C 2 394 ? 223.334 198.478 192.742 1.00 62.83  ? 394  ASN A O   1 
ATOM   7685 C CB  . ASN C 2 394 ? 225.769 196.701 193.947 1.00 62.83  ? 394  ASN A CB  1 
ATOM   7686 C CG  . ASN C 2 394 ? 224.964 195.629 193.241 1.00 62.83  ? 394  ASN A CG  1 
ATOM   7687 O OD1 . ASN C 2 394 ? 224.563 194.637 193.849 1.00 62.83  ? 394  ASN A OD1 1 
ATOM   7688 N ND2 . ASN C 2 394 ? 224.722 195.824 191.952 1.00 62.83  ? 394  ASN A ND2 1 
ATOM   7689 N N   . VAL C 2 395 ? 225.221 199.704 192.941 1.00 59.76  ? 395  VAL A N   1 
ATOM   7690 C CA  . VAL C 2 395 ? 224.915 200.636 191.862 1.00 59.76  ? 395  VAL A CA  1 
ATOM   7691 C C   . VAL C 2 395 ? 226.029 200.552 190.829 1.00 59.76  ? 395  VAL A C   1 
ATOM   7692 O O   . VAL C 2 395 ? 227.213 200.576 191.182 1.00 59.76  ? 395  VAL A O   1 
ATOM   7693 C CB  . VAL C 2 395 ? 224.760 202.076 192.384 1.00 59.76  ? 395  VAL A CB  1 
ATOM   7694 C CG1 . VAL C 2 395 ? 224.413 203.022 191.244 1.00 59.76  ? 395  VAL A CG1 1 
ATOM   7695 C CG2 . VAL C 2 395 ? 223.701 202.136 193.474 1.00 59.76  ? 395  VAL A CG2 1 
ATOM   7696 N N   . TYR C 2 396 ? 225.649 200.453 189.558 1.00 57.49  ? 396  TYR A N   1 
ATOM   7697 C CA  . TYR C 2 396 ? 226.600 200.413 188.456 1.00 57.49  ? 396  TYR A CA  1 
ATOM   7698 C C   . TYR C 2 396 ? 226.613 201.758 187.744 1.00 57.49  ? 396  TYR A C   1 
ATOM   7699 O O   . TYR C 2 396 ? 225.560 202.266 187.345 1.00 57.49  ? 396  TYR A O   1 
ATOM   7700 C CB  . TYR C 2 396 ? 226.253 199.298 187.468 1.00 57.49  ? 396  TYR A CB  1 
ATOM   7701 C CG  . TYR C 2 396 ? 226.390 197.906 188.037 1.00 57.49  ? 396  TYR A CG  1 
ATOM   7702 C CD1 . TYR C 2 396 ? 227.641 197.348 188.263 1.00 57.49  ? 396  TYR A CD1 1 
ATOM   7703 C CD2 . TYR C 2 396 ? 225.270 197.144 188.337 1.00 57.49  ? 396  TYR A CD2 1 
ATOM   7704 C CE1 . TYR C 2 396 ? 227.772 196.074 188.780 1.00 57.49  ? 396  TYR A CE1 1 
ATOM   7705 C CE2 . TYR C 2 396 ? 225.391 195.869 188.852 1.00 57.49  ? 396  TYR A CE2 1 
ATOM   7706 C CZ  . TYR C 2 396 ? 226.644 195.339 189.073 1.00 57.49  ? 396  TYR A CZ  1 
ATOM   7707 O OH  . TYR C 2 396 ? 226.768 194.070 189.587 1.00 57.49  ? 396  TYR A OH  1 
ATOM   7708 N N   . ALA C 2 397 ? 227.805 202.329 187.587 1.00 56.48  ? 397  ALA A N   1 
ATOM   7709 C CA  . ALA C 2 397 ? 227.991 203.616 186.927 1.00 56.48  ? 397  ALA A CA  1 
ATOM   7710 C C   . ALA C 2 397 ? 228.619 203.371 185.561 1.00 56.48  ? 397  ALA A C   1 
ATOM   7711 O O   . ALA C 2 397 ? 229.803 203.029 185.468 1.00 56.48  ? 397  ALA A O   1 
ATOM   7712 C CB  . ALA C 2 397 ? 228.858 204.545 187.775 1.00 56.48  ? 397  ALA A CB  1 
ATOM   7713 N N   . ASP C 2 398 ? 227.826 203.543 184.506 1.00 56.79  ? 398  ASP A N   1 
ATOM   7714 C CA  . ASP C 2 398 ? 228.285 203.364 183.133 1.00 56.79  ? 398  ASP A CA  1 
ATOM   7715 C C   . ASP C 2 398 ? 228.599 204.736 182.549 1.00 56.79  ? 398  ASP A C   1 
ATOM   7716 O O   . ASP C 2 398 ? 227.688 205.526 182.280 1.00 56.79  ? 398  ASP A O   1 
ATOM   7717 C CB  . ASP C 2 398 ? 227.231 202.638 182.300 1.00 56.79  ? 398  ASP A CB  1 
ATOM   7718 C CG  . ASP C 2 398 ? 226.768 201.347 182.945 1.00 56.79  ? 398  ASP A CG  1 
ATOM   7719 O OD1 . ASP C 2 398 ? 227.557 200.741 183.700 1.00 56.79  ? 398  ASP A OD1 1 
ATOM   7720 O OD2 . ASP C 2 398 ? 225.614 200.937 182.699 1.00 56.79  ? 398  ASP A OD2 1 
ATOM   7721 N N   . SER C 2 399 ? 229.883 205.016 182.350 1.00 56.60  ? 399  SER A N   1 
ATOM   7722 C CA  . SER C 2 399 ? 230.345 206.312 181.870 1.00 56.60  ? 399  SER A CA  1 
ATOM   7723 C C   . SER C 2 399 ? 230.931 206.167 180.473 1.00 56.60  ? 399  SER A C   1 
ATOM   7724 O O   . SER C 2 399 ? 231.715 205.247 180.215 1.00 56.60  ? 399  SER A O   1 
ATOM   7725 C CB  . SER C 2 399 ? 231.388 206.904 182.820 1.00 56.60  ? 399  SER A CB  1 
ATOM   7726 O OG  . SER C 2 399 ? 232.510 206.048 182.941 1.00 56.60  ? 399  SER A OG  1 
ATOM   7727 N N   . PHE C 2 400 ? 230.554 207.079 179.580 1.00 56.44  ? 400  PHE A N   1 
ATOM   7728 C CA  . PHE C 2 400 ? 231.063 207.102 178.214 1.00 56.44  ? 400  PHE A CA  1 
ATOM   7729 C C   . PHE C 2 400 ? 230.716 208.452 177.601 1.00 56.44  ? 400  PHE A C   1 
ATOM   7730 O O   . PHE C 2 400 ? 229.916 209.217 178.146 1.00 56.44  ? 400  PHE A O   1 
ATOM   7731 C CB  . PHE C 2 400 ? 230.498 205.950 177.375 1.00 56.44  ? 400  PHE A CB  1 
ATOM   7732 C CG  . PHE C 2 400 ? 228.997 205.872 177.377 1.00 56.44  ? 400  PHE A CG  1 
ATOM   7733 C CD1 . PHE C 2 400 ? 228.328 205.167 178.363 1.00 56.44  ? 400  PHE A CD1 1 
ATOM   7734 C CD2 . PHE C 2 400 ? 228.257 206.492 176.385 1.00 56.44  ? 400  PHE A CD2 1 
ATOM   7735 C CE1 . PHE C 2 400 ? 226.949 205.090 178.365 1.00 56.44  ? 400  PHE A CE1 1 
ATOM   7736 C CE2 . PHE C 2 400 ? 226.877 206.416 176.381 1.00 56.44  ? 400  PHE A CE2 1 
ATOM   7737 C CZ  . PHE C 2 400 ? 226.223 205.715 177.373 1.00 56.44  ? 400  PHE A CZ  1 
ATOM   7738 N N   . VAL C 2 401 ? 231.333 208.736 176.456 1.00 56.79  ? 401  VAL A N   1 
ATOM   7739 C CA  . VAL C 2 401 ? 231.132 209.983 175.728 1.00 56.79  ? 401  VAL A CA  1 
ATOM   7740 C C   . VAL C 2 401 ? 230.294 209.688 174.493 1.00 56.79  ? 401  VAL A C   1 
ATOM   7741 O O   . VAL C 2 401 ? 230.598 208.759 173.735 1.00 56.79  ? 401  VAL A O   1 
ATOM   7742 C CB  . VAL C 2 401 ? 232.471 210.635 175.343 1.00 56.79  ? 401  VAL A CB  1 
ATOM   7743 C CG1 . VAL C 2 401 ? 232.235 211.868 174.485 1.00 56.79  ? 401  VAL A CG1 1 
ATOM   7744 C CG2 . VAL C 2 401 ? 233.257 210.997 176.590 1.00 56.79  ? 401  VAL A CG2 1 
ATOM   7745 N N   . ILE C 2 402 ? 229.240 210.480 174.290 1.00 57.23  ? 402  ILE A N   1 
ATOM   7746 C CA  . ILE C 2 402 ? 228.324 210.297 173.175 1.00 57.23  ? 402  ILE A CA  1 
ATOM   7747 C C   . ILE C 2 402 ? 228.078 211.650 172.518 1.00 57.23  ? 402  ILE A C   1 
ATOM   7748 O O   . ILE C 2 402 ? 228.338 212.707 173.097 1.00 57.23  ? 402  ILE A O   1 
ATOM   7749 C CB  . ILE C 2 402 ? 226.992 209.653 173.621 1.00 57.23  ? 402  ILE A CB  1 
ATOM   7750 C CG1 . ILE C 2 402 ? 226.350 208.886 172.463 1.00 57.23  ? 402  ILE A CG1 1 
ATOM   7751 C CG2 . ILE C 2 402 ? 226.038 210.706 174.166 1.00 57.23  ? 402  ILE A CG2 1 
ATOM   7752 C CD1 . ILE C 2 402 ? 227.231 207.794 171.903 1.00 57.23  ? 402  ILE A CD1 1 
ATOM   7753 N N   . ARG C 2 403 ? 227.579 211.603 171.286 1.00 54.36  ? 403  ARG A N   1 
ATOM   7754 C CA  . ARG C 2 403 ? 227.278 212.823 170.556 1.00 54.36  ? 403  ARG A CA  1 
ATOM   7755 C C   . ARG C 2 403 ? 226.004 213.467 171.102 1.00 54.36  ? 403  ARG A C   1 
ATOM   7756 O O   . ARG C 2 403 ? 225.157 212.813 171.716 1.00 54.36  ? 403  ARG A O   1 
ATOM   7757 C CB  . ARG C 2 403 ? 227.135 212.531 169.062 1.00 54.36  ? 403  ARG A CB  1 
ATOM   7758 C CG  . ARG C 2 403 ? 227.408 213.726 168.165 1.00 54.36  ? 403  ARG A CG  1 
ATOM   7759 C CD  . ARG C 2 403 ? 227.438 213.328 166.699 1.00 54.36  ? 403  ARG A CD  1 
ATOM   7760 N NE  . ARG C 2 403 ? 226.140 212.857 166.229 1.00 54.36  ? 403  ARG A NE  1 
ATOM   7761 C CZ  . ARG C 2 403 ? 225.894 212.470 164.982 1.00 54.36  ? 403  ARG A CZ  1 
ATOM   7762 N NH1 . ARG C 2 403 ? 224.682 212.056 164.641 1.00 54.36  ? 403  ARG A NH1 1 
ATOM   7763 N NH2 . ARG C 2 403 ? 226.860 212.496 164.074 1.00 54.36  ? 403  ARG A NH2 1 
ATOM   7764 N N   . GLY C 2 404 ? 225.877 214.774 170.867 1.00 54.14  ? 404  GLY A N   1 
ATOM   7765 C CA  . GLY C 2 404 ? 224.783 215.521 171.466 1.00 54.14  ? 404  GLY A CA  1 
ATOM   7766 C C   . GLY C 2 404 ? 223.424 215.169 170.891 1.00 54.14  ? 404  GLY A C   1 
ATOM   7767 O O   . GLY C 2 404 ? 222.429 215.115 171.619 1.00 54.14  ? 404  GLY A O   1 
ATOM   7768 N N   . ASP C 2 405 ? 223.358 214.926 169.583 1.00 56.38  ? 405  ASP A N   1 
ATOM   7769 C CA  . ASP C 2 405 ? 222.085 214.641 168.931 1.00 56.38  ? 405  ASP A CA  1 
ATOM   7770 C C   . ASP C 2 405 ? 221.607 213.211 169.149 1.00 56.38  ? 405  ASP A C   1 
ATOM   7771 O O   . ASP C 2 405 ? 220.552 212.843 168.621 1.00 56.38  ? 405  ASP A O   1 
ATOM   7772 C CB  . ASP C 2 405 ? 222.184 214.928 167.430 1.00 56.38  ? 405  ASP A CB  1 
ATOM   7773 C CG  . ASP C 2 405 ? 223.300 214.154 166.757 1.00 56.38  ? 405  ASP A CG  1 
ATOM   7774 O OD1 . ASP C 2 405 ? 224.099 213.511 167.470 1.00 56.38  ? 405  ASP A OD1 1 
ATOM   7775 O OD2 . ASP C 2 405 ? 223.377 214.188 165.511 1.00 56.38  ? 405  ASP A OD2 1 
ATOM   7776 N N   . GLU C 2 406 ? 222.346 212.401 169.907 1.00 56.60  ? 406  GLU A N   1 
ATOM   7777 C CA  . GLU C 2 406 ? 221.961 211.022 170.180 1.00 56.60  ? 406  GLU A CA  1 
ATOM   7778 C C   . GLU C 2 406 ? 221.986 210.729 171.675 1.00 56.60  ? 406  GLU A C   1 
ATOM   7779 O O   . GLU C 2 406 ? 222.174 209.581 172.087 1.00 56.60  ? 406  GLU A O   1 
ATOM   7780 C CB  . GLU C 2 406 ? 222.861 210.046 169.422 1.00 56.60  ? 406  GLU A CB  1 
ATOM   7781 C CG  . GLU C 2 406 ? 224.344 210.242 169.676 1.00 56.60  ? 406  GLU A CG  1 
ATOM   7782 C CD  . GLU C 2 406 ? 225.207 209.415 168.745 1.00 56.60  ? 406  GLU A CD  1 
ATOM   7783 O OE1 . GLU C 2 406 ? 224.662 208.849 167.774 1.00 56.60  ? 406  GLU A OE1 1 
ATOM   7784 O OE2 . GLU C 2 406 ? 226.429 209.328 168.984 1.00 56.60  ? 406  GLU A OE2 1 
ATOM   7785 N N   . VAL C 2 407 ? 221.795 211.760 172.501 1.00 55.48  ? 407  VAL A N   1 
ATOM   7786 C CA  . VAL C 2 407 ? 221.743 211.553 173.944 1.00 55.48  ? 407  VAL A CA  1 
ATOM   7787 C C   . VAL C 2 407 ? 220.422 210.908 174.342 1.00 55.48  ? 407  VAL A C   1 
ATOM   7788 O O   . VAL C 2 407 ? 220.374 210.064 175.245 1.00 55.48  ? 407  VAL A O   1 
ATOM   7789 C CB  . VAL C 2 407 ? 221.971 212.885 174.683 1.00 55.48  ? 407  VAL A CB  1 
ATOM   7790 C CG1 . VAL C 2 407 ? 221.872 212.687 176.188 1.00 55.48  ? 407  VAL A CG1 1 
ATOM   7791 C CG2 . VAL C 2 407 ? 223.322 213.472 174.313 1.00 55.48  ? 407  VAL A CG2 1 
ATOM   7792 N N   . ARG C 2 408 ? 219.331 211.282 173.671 1.00 56.11  ? 408  ARG A N   1 
ATOM   7793 C CA  . ARG C 2 408 ? 218.025 210.724 173.998 1.00 56.11  ? 408  ARG A CA  1 
ATOM   7794 C C   . ARG C 2 408 ? 217.897 209.255 173.614 1.00 56.11  ? 408  ARG A C   1 
ATOM   7795 O O   . ARG C 2 408 ? 216.917 208.615 174.008 1.00 56.11  ? 408  ARG A O   1 
ATOM   7796 C CB  . ARG C 2 408 ? 216.914 211.541 173.329 1.00 56.11  ? 408  ARG A CB  1 
ATOM   7797 C CG  . ARG C 2 408 ? 216.527 211.102 171.922 1.00 56.11  ? 408  ARG A CG  1 
ATOM   7798 C CD  . ARG C 2 408 ? 217.614 211.394 170.902 1.00 56.11  ? 408  ARG A CD  1 
ATOM   7799 N NE  . ARG C 2 408 ? 217.064 211.561 169.559 1.00 56.11  ? 408  ARG A NE  1 
ATOM   7800 C CZ  . ARG C 2 408 ? 216.714 210.558 168.760 1.00 56.11  ? 408  ARG A CZ  1 
ATOM   7801 N NH1 . ARG C 2 408 ? 216.223 210.810 167.555 1.00 56.11  ? 408  ARG A NH1 1 
ATOM   7802 N NH2 . ARG C 2 408 ? 216.848 209.303 169.165 1.00 56.11  ? 408  ARG A NH2 1 
ATOM   7803 N N   . GLN C 2 409 ? 218.857 208.708 172.863 1.00 56.58  ? 409  GLN A N   1 
ATOM   7804 C CA  . GLN C 2 409 ? 218.854 207.277 172.582 1.00 56.58  ? 409  GLN A CA  1 
ATOM   7805 C C   . GLN C 2 409 ? 219.193 206.450 173.814 1.00 56.58  ? 409  GLN A C   1 
ATOM   7806 O O   . GLN C 2 409 ? 218.908 205.248 173.836 1.00 56.58  ? 409  GLN A O   1 
ATOM   7807 C CB  . GLN C 2 409 ? 219.835 206.953 171.456 1.00 56.58  ? 409  GLN A CB  1 
ATOM   7808 C CG  . GLN C 2 409 ? 219.477 207.578 170.120 1.00 56.58  ? 409  GLN A CG  1 
ATOM   7809 C CD  . GLN C 2 409 ? 220.378 207.108 168.997 1.00 56.58  ? 409  GLN A CD  1 
ATOM   7810 O OE1 . GLN C 2 409 ? 221.237 206.250 169.193 1.00 56.58  ? 409  GLN A OE1 1 
ATOM   7811 N NE2 . GLN C 2 409 ? 220.184 207.669 167.809 1.00 56.58  ? 409  GLN A NE2 1 
ATOM   7812 N N   . ILE C 2 410 ? 219.793 207.060 174.832 1.00 56.88  ? 410  ILE A N   1 
ATOM   7813 C CA  . ILE C 2 410 ? 220.107 206.349 176.082 1.00 56.88  ? 410  ILE A CA  1 
ATOM   7814 C C   . ILE C 2 410 ? 218.867 206.479 176.958 1.00 56.88  ? 410  ILE A C   1 
ATOM   7815 O O   . ILE C 2 410 ? 218.755 207.345 177.830 1.00 56.88  ? 410  ILE A O   1 
ATOM   7816 C CB  . ILE C 2 410 ? 221.372 206.890 176.754 1.00 56.88  ? 410  ILE A CB  1 
ATOM   7817 C CG1 . ILE C 2 410 ? 222.537 206.904 175.762 1.00 56.88  ? 410  ILE A CG1 1 
ATOM   7818 C CG2 . ILE C 2 410 ? 221.728 206.054 177.974 1.00 56.88  ? 410  ILE A CG2 1 
ATOM   7819 C CD1 . ILE C 2 410 ? 222.888 205.540 175.213 1.00 56.88  ? 410  ILE A CD1 1 
ATOM   7820 N N   . ALA C 2 411 ? 217.908 205.586 176.721 1.00 59.17  ? 411  ALA A N   1 
ATOM   7821 C CA  . ALA C 2 411 ? 216.633 205.581 177.425 1.00 59.17  ? 411  ALA A CA  1 
ATOM   7822 C C   . ALA C 2 411 ? 215.913 204.264 177.161 1.00 59.17  ? 411  ALA A C   1 
ATOM   7823 O O   . ALA C 2 411 ? 216.112 203.651 176.105 1.00 59.17  ? 411  ALA A O   1 
ATOM   7824 C CB  . ALA C 2 411 ? 215.766 206.764 176.990 1.00 59.17  ? 411  ALA A CB  1 
ATOM   7825 N N   . PRO C 2 412 ? 215.083 203.793 178.091 1.00 60.50  ? 412  PRO A N   1 
ATOM   7826 C CA  . PRO C 2 412 ? 214.361 202.530 177.868 1.00 60.50  ? 412  PRO A CA  1 
ATOM   7827 C C   . PRO C 2 412 ? 213.388 202.647 176.705 1.00 60.50  ? 412  PRO A C   1 
ATOM   7828 O O   . PRO C 2 412 ? 212.503 203.506 176.694 1.00 60.50  ? 412  PRO A O   1 
ATOM   7829 C CB  . PRO C 2 412 ? 213.633 202.301 179.198 1.00 60.50  ? 412  PRO A CB  1 
ATOM   7830 C CG  . PRO C 2 412 ? 214.393 203.110 180.198 1.00 60.50  ? 412  PRO A CG  1 
ATOM   7831 C CD  . PRO C 2 412 ? 214.873 204.314 179.452 1.00 60.50  ? 412  PRO A CD  1 
ATOM   7832 N N   . GLY C 2 413 ? 213.558 201.770 175.720 1.00 60.35  ? 413  GLY A N   1 
ATOM   7833 C CA  . GLY C 2 413 ? 212.666 201.737 174.580 1.00 60.35  ? 413  GLY A CA  1 
ATOM   7834 C C   . GLY C 2 413 ? 213.037 202.653 173.439 1.00 60.35  ? 413  GLY A C   1 
ATOM   7835 O O   . GLY C 2 413 ? 212.148 203.108 172.711 1.00 60.35  ? 413  GLY A O   1 
ATOM   7836 N N   . GLN C 2 414 ? 214.321 202.942 173.255 1.00 60.42  ? 414  GLN A N   1 
ATOM   7837 C CA  . GLN C 2 414 ? 214.788 203.794 172.173 1.00 60.42  ? 414  GLN A CA  1 
ATOM   7838 C C   . GLN C 2 414 ? 215.621 202.985 171.188 1.00 60.42  ? 414  GLN A C   1 
ATOM   7839 O O   . GLN C 2 414 ? 216.284 202.012 171.558 1.00 60.42  ? 414  GLN A O   1 
ATOM   7840 C CB  . GLN C 2 414 ? 215.612 204.968 172.709 1.00 60.42  ? 414  GLN A CB  1 
ATOM   7841 C CG  . GLN C 2 414 ? 214.823 205.940 173.570 1.00 60.42  ? 414  GLN A CG  1 
ATOM   7842 C CD  . GLN C 2 414 ? 213.796 206.726 172.779 1.00 60.42  ? 414  GLN A CD  1 
ATOM   7843 O OE1 . GLN C 2 414 ? 212.768 207.140 173.315 1.00 60.42  ? 414  GLN A OE1 1 
ATOM   7844 N NE2 . GLN C 2 414 ? 214.073 206.943 171.498 1.00 60.42  ? 414  GLN A NE2 1 
ATOM   7845 N N   . THR C 2 415 ? 215.577 203.396 169.927 1.00 60.30  ? 415  THR A N   1 
ATOM   7846 C CA  . THR C 2 415 ? 216.327 202.763 168.852 1.00 60.30  ? 415  THR A CA  1 
ATOM   7847 C C   . THR C 2 415 ? 217.355 203.746 168.299 1.00 60.30  ? 415  THR A C   1 
ATOM   7848 O O   . THR C 2 415 ? 217.498 204.871 168.783 1.00 60.30  ? 415  THR A O   1 
ATOM   7849 C CB  . THR C 2 415 ? 215.389 202.274 167.744 1.00 60.30  ? 415  THR A CB  1 
ATOM   7850 O OG1 . THR C 2 415 ? 216.156 201.641 166.712 1.00 60.30  ? 415  THR A OG1 1 
ATOM   7851 C CG2 . THR C 2 415 ? 214.615 203.440 167.149 1.00 60.30  ? 415  THR A CG2 1 
ATOM   7852 N N   . GLY C 2 416 ? 218.076 203.306 167.269 1.00 58.33  ? 416  GLY A N   1 
ATOM   7853 C CA  . GLY C 2 416 ? 219.091 204.104 166.623 1.00 58.33  ? 416  GLY A CA  1 
ATOM   7854 C C   . GLY C 2 416 ? 220.359 203.302 166.441 1.00 58.33  ? 416  GLY A C   1 
ATOM   7855 O O   . GLY C 2 416 ? 220.339 202.066 166.418 1.00 58.33  ? 416  GLY A O   1 
ATOM   7856 N N   . LYS C 2 417 ? 221.475 204.016 166.307 1.00 56.25  ? 417  LYS A N   1 
ATOM   7857 C CA  . LYS C 2 417 ? 222.773 203.376 166.137 1.00 56.25  ? 417  LYS A CA  1 
ATOM   7858 C C   . LYS C 2 417 ? 223.454 203.091 167.469 1.00 56.25  ? 417  LYS A C   1 
ATOM   7859 O O   . LYS C 2 417 ? 224.126 202.065 167.615 1.00 56.25  ? 417  LYS A O   1 
ATOM   7860 C CB  . LYS C 2 417 ? 223.680 204.248 165.265 1.00 56.25  ? 417  LYS A CB  1 
ATOM   7861 C CG  . LYS C 2 417 ? 224.249 203.535 164.052 1.00 56.25  ? 417  LYS A CG  1 
ATOM   7862 C CD  . LYS C 2 417 ? 223.148 203.108 163.097 1.00 56.25  ? 417  LYS A CD  1 
ATOM   7863 C CE  . LYS C 2 417 ? 223.720 202.429 161.865 1.00 56.25  ? 417  LYS A CE  1 
ATOM   7864 N NZ  . LYS C 2 417 ? 222.654 202.020 160.910 1.00 56.25  ? 417  LYS A NZ  1 
ATOM   7865 N N   . ILE C 2 418 ? 223.294 203.984 168.445 1.00 57.12  ? 418  ILE A N   1 
ATOM   7866 C CA  . ILE C 2 418 ? 223.917 203.784 169.748 1.00 57.12  ? 418  ILE A CA  1 
ATOM   7867 C C   . ILE C 2 418 ? 223.086 202.842 170.608 1.00 57.12  ? 418  ILE A C   1 
ATOM   7868 O O   . ILE C 2 418 ? 223.629 201.982 171.311 1.00 57.12  ? 418  ILE A O   1 
ATOM   7869 C CB  . ILE C 2 418 ? 224.135 205.142 170.440 1.00 57.12  ? 418  ILE A CB  1 
ATOM   7870 C CG1 . ILE C 2 418 ? 224.985 206.055 169.557 1.00 57.12  ? 418  ILE A CG1 1 
ATOM   7871 C CG2 . ILE C 2 418 ? 224.784 204.953 171.801 1.00 57.12  ? 418  ILE A CG2 1 
ATOM   7872 C CD1 . ILE C 2 418 ? 226.329 205.470 169.186 1.00 57.12  ? 418  ILE A CD1 1 
ATOM   7873 N N   . ALA C 2 419 ? 221.760 202.980 170.563 1.00 57.76  ? 419  ALA A N   1 
ATOM   7874 C CA  . ALA C 2 419 ? 220.884 202.152 171.381 1.00 57.76  ? 419  ALA A CA  1 
ATOM   7875 C C   . ALA C 2 419 ? 220.753 200.727 170.861 1.00 57.76  ? 419  ALA A C   1 
ATOM   7876 O O   . ALA C 2 419 ? 220.128 199.900 171.532 1.00 57.76  ? 419  ALA A O   1 
ATOM   7877 C CB  . ALA C 2 419 ? 219.499 202.793 171.480 1.00 57.76  ? 419  ALA A CB  1 
ATOM   7878 N N   . ASP C 2 420 ? 221.313 200.420 169.694 1.00 59.34  ? 420  ASP A N   1 
ATOM   7879 C CA  . ASP C 2 420 ? 221.230 199.084 169.123 1.00 59.34  ? 420  ASP A CA  1 
ATOM   7880 C C   . ASP C 2 420 ? 222.575 198.395 168.962 1.00 59.34  ? 420  ASP A C   1 
ATOM   7881 O O   . ASP C 2 420 ? 222.635 197.168 169.059 1.00 59.34  ? 420  ASP A O   1 
ATOM   7882 C CB  . ASP C 2 420 ? 220.537 199.127 167.752 1.00 59.34  ? 420  ASP A CB  1 
ATOM   7883 C CG  . ASP C 2 420 ? 219.080 199.533 167.846 1.00 59.34  ? 420  ASP A CG  1 
ATOM   7884 O OD1 . ASP C 2 420 ? 218.573 199.679 168.978 1.00 59.34  ? 420  ASP A OD1 1 
ATOM   7885 O OD2 . ASP C 2 420 ? 218.442 199.706 166.787 1.00 59.34  ? 420  ASP A OD2 1 
ATOM   7886 N N   . TYR C 2 421 ? 223.653 199.142 168.722 1.00 57.64  ? 421  TYR A N   1 
ATOM   7887 C CA  . TYR C 2 421 ? 224.956 198.552 168.461 1.00 57.64  ? 421  TYR A CA  1 
ATOM   7888 C C   . TYR C 2 421 ? 226.013 198.885 169.503 1.00 57.64  ? 421  TYR A C   1 
ATOM   7889 O O   . TYR C 2 421 ? 227.056 198.221 169.527 1.00 57.64  ? 421  TYR A O   1 
ATOM   7890 C CB  . TYR C 2 421 ? 225.475 198.988 167.081 1.00 57.64  ? 421  TYR A CB  1 
ATOM   7891 C CG  . TYR C 2 421 ? 224.610 198.547 165.922 1.00 57.64  ? 421  TYR A CG  1 
ATOM   7892 C CD1 . TYR C 2 421 ? 223.829 197.402 166.007 1.00 57.64  ? 421  TYR A CD1 1 
ATOM   7893 C CD2 . TYR C 2 421 ? 224.574 199.276 164.741 1.00 57.64  ? 421  TYR A CD2 1 
ATOM   7894 C CE1 . TYR C 2 421 ? 223.037 196.997 164.950 1.00 57.64  ? 421  TYR A CE1 1 
ATOM   7895 C CE2 . TYR C 2 421 ? 223.786 198.879 163.679 1.00 57.64  ? 421  TYR A CE2 1 
ATOM   7896 C CZ  . TYR C 2 421 ? 223.020 197.739 163.788 1.00 57.64  ? 421  TYR A CZ  1 
ATOM   7897 O OH  . TYR C 2 421 ? 222.234 197.339 162.733 1.00 57.64  ? 421  TYR A OH  1 
ATOM   7898 N N   . ASN C 2 422 ? 225.787 199.881 170.357 1.00 56.58  ? 422  ASN A N   1 
ATOM   7899 C CA  . ASN C 2 422 ? 226.790 200.302 171.327 1.00 56.58  ? 422  ASN A CA  1 
ATOM   7900 C C   . ASN C 2 422 ? 226.348 200.099 172.767 1.00 56.58  ? 422  ASN A C   1 
ATOM   7901 O O   . ASN C 2 422 ? 227.066 199.460 173.545 1.00 56.58  ? 422  ASN A O   1 
ATOM   7902 C CB  . ASN C 2 422 ? 227.155 201.777 171.094 1.00 56.58  ? 422  ASN A CB  1 
ATOM   7903 C CG  . ASN C 2 422 ? 227.806 202.009 169.745 1.00 56.58  ? 422  ASN A CG  1 
ATOM   7904 O OD1 . ASN C 2 422 ? 229.030 202.018 169.627 1.00 56.58  ? 422  ASN A OD1 1 
ATOM   7905 N ND2 . ASN C 2 422 ? 226.987 202.195 168.717 1.00 56.58  ? 422  ASN A ND2 1 
ATOM   7906 N N   . TYR C 2 423 ? 225.185 200.621 173.148 1.00 57.68  ? 423  TYR A N   1 
ATOM   7907 C CA  . TYR C 2 423 ? 224.728 200.543 174.532 1.00 57.68  ? 423  TYR A CA  1 
ATOM   7908 C C   . TYR C 2 423 ? 223.210 200.596 174.545 1.00 57.68  ? 423  TYR A C   1 
ATOM   7909 O O   . TYR C 2 423 ? 222.620 201.561 174.051 1.00 57.68  ? 423  TYR A O   1 
ATOM   7910 C CB  . TYR C 2 423 ? 225.318 201.683 175.366 1.00 57.68  ? 423  TYR A CB  1 
ATOM   7911 C CG  . TYR C 2 423 ? 224.957 201.633 176.833 1.00 57.68  ? 423  TYR A CG  1 
ATOM   7912 C CD1 . TYR C 2 423 ? 225.683 200.850 177.720 1.00 57.68  ? 423  TYR A CD1 1 
ATOM   7913 C CD2 . TYR C 2 423 ? 223.897 202.376 177.333 1.00 57.68  ? 423  TYR A CD2 1 
ATOM   7914 C CE1 . TYR C 2 423 ? 225.360 200.803 179.062 1.00 57.68  ? 423  TYR A CE1 1 
ATOM   7915 C CE2 . TYR C 2 423 ? 223.567 202.337 178.673 1.00 57.68  ? 423  TYR A CE2 1 
ATOM   7916 C CZ  . TYR C 2 423 ? 224.301 201.548 179.533 1.00 57.68  ? 423  TYR A CZ  1 
ATOM   7917 O OH  . TYR C 2 423 ? 223.976 201.505 180.869 1.00 57.68  ? 423  TYR A OH  1 
ATOM   7918 N N   . LYS C 2 424 ? 222.581 199.570 175.114 1.00 57.98  ? 424  LYS A N   1 
ATOM   7919 C CA  . LYS C 2 424 ? 221.130 199.469 175.153 1.00 57.98  ? 424  LYS A CA  1 
ATOM   7920 C C   . LYS C 2 424 ? 220.661 199.293 176.589 1.00 57.98  ? 424  LYS A C   1 
ATOM   7921 O O   . LYS C 2 424 ? 221.243 198.516 177.352 1.00 57.98  ? 424  LYS A O   1 
ATOM   7922 C CB  . LYS C 2 424 ? 220.630 198.301 174.294 1.00 57.98  ? 424  LYS A CB  1 
ATOM   7923 C CG  . LYS C 2 424 ? 219.117 198.218 174.182 1.00 57.98  ? 424  LYS A CG  1 
ATOM   7924 C CD  . LYS C 2 424 ? 218.693 197.098 173.248 1.00 57.98  ? 424  LYS A CD  1 
ATOM   7925 C CE  . LYS C 2 424 ? 217.182 197.053 173.095 1.00 57.98  ? 424  LYS A CE  1 
ATOM   7926 N NZ  . LYS C 2 424 ? 216.498 196.840 174.400 1.00 57.98  ? 424  LYS A NZ  1 
ATOM   7927 N N   . LEU C 2 425 ? 219.606 200.019 176.949 1.00 58.79  ? 425  LEU A N   1 
ATOM   7928 C CA  . LEU C 2 425 ? 218.977 199.940 178.258 1.00 58.79  ? 425  LEU A CA  1 
ATOM   7929 C C   . LEU C 2 425 ? 217.748 199.042 178.207 1.00 58.79  ? 425  LEU A C   1 
ATOM   7930 O O   . LEU C 2 425 ? 217.012 199.054 177.214 1.00 58.79  ? 425  LEU A O   1 
ATOM   7931 C CB  . LEU C 2 425 ? 218.565 201.329 178.749 1.00 58.79  ? 425  LEU A CB  1 
ATOM   7932 C CG  . LEU C 2 425 ? 219.689 202.292 179.131 1.00 58.79  ? 425  LEU A CG  1 
ATOM   7933 C CD1 . LEU C 2 425 ? 219.127 203.663 179.461 1.00 58.79  ? 425  LEU A CD1 1 
ATOM   7934 C CD2 . LEU C 2 425 ? 220.477 201.742 180.306 1.00 58.79  ? 425  LEU A CD2 1 
ATOM   7935 N N   . PRO C 2 426 ? 217.504 198.255 179.251 1.00 60.72  ? 426  PRO A N   1 
ATOM   7936 C CA  . PRO C 2 426 ? 216.316 197.398 179.263 1.00 60.72  ? 426  PRO A CA  1 
ATOM   7937 C C   . PRO C 2 426 ? 215.041 198.218 179.383 1.00 60.72  ? 426  PRO A C   1 
ATOM   7938 O O   . PRO C 2 426 ? 215.047 199.379 179.795 1.00 60.72  ? 426  PRO A O   1 
ATOM   7939 C CB  . PRO C 2 426 ? 216.528 196.515 180.497 1.00 60.72  ? 426  PRO A CB  1 
ATOM   7940 C CG  . PRO C 2 426 ? 217.401 197.332 181.389 1.00 60.72  ? 426  PRO A CG  1 
ATOM   7941 C CD  . PRO C 2 426 ? 218.311 198.102 180.474 1.00 60.72  ? 426  PRO A CD  1 
ATOM   7942 N N   . ASP C 2 427 ? 213.928 197.584 179.007 1.00 64.58  ? 427  ASP A N   1 
ATOM   7943 C CA  . ASP C 2 427 ? 212.638 198.262 179.075 1.00 64.58  ? 427  ASP A CA  1 
ATOM   7944 C C   . ASP C 2 427 ? 212.226 198.545 180.514 1.00 64.58  ? 427  ASP A C   1 
ATOM   7945 O O   . ASP C 2 427 ? 211.532 199.533 180.776 1.00 64.58  ? 427  ASP A O   1 
ATOM   7946 C CB  . ASP C 2 427 ? 211.569 197.429 178.369 1.00 64.58  ? 427  ASP A CB  1 
ATOM   7947 C CG  . ASP C 2 427 ? 210.222 198.122 178.330 1.00 64.58  ? 427  ASP A CG  1 
ATOM   7948 O OD1 . ASP C 2 427 ? 210.093 199.132 177.607 1.00 64.58  ? 427  ASP A OD1 1 
ATOM   7949 O OD2 . ASP C 2 427 ? 209.292 197.657 179.023 1.00 64.58  ? 427  ASP A OD2 1 
ATOM   7950 N N   . ASP C 2 428 ? 212.642 197.699 181.454 1.00 62.90  ? 428  ASP A N   1 
ATOM   7951 C CA  . ASP C 2 428 ? 212.346 197.875 182.874 1.00 62.90  ? 428  ASP A CA  1 
ATOM   7952 C C   . ASP C 2 428 ? 213.526 198.472 183.628 1.00 62.90  ? 428  ASP A C   1 
ATOM   7953 O O   . ASP C 2 428 ? 213.776 198.127 184.786 1.00 62.90  ? 428  ASP A O   1 
ATOM   7954 C CB  . ASP C 2 428 ? 211.927 196.547 183.496 1.00 62.90  ? 428  ASP A CB  1 
ATOM   7955 C CG  . ASP C 2 428 ? 212.944 195.446 183.263 1.00 62.90  ? 428  ASP A CG  1 
ATOM   7956 O OD1 . ASP C 2 428 ? 213.914 195.678 182.511 1.00 62.90  ? 428  ASP A OD1 1 
ATOM   7957 O OD2 . ASP C 2 428 ? 212.774 194.348 183.833 1.00 62.90  ? 428  ASP A OD2 1 
ATOM   7958 N N   . PHE C 2 429 ? 214.272 199.368 182.985 1.00 60.30  ? 429  PHE A N   1 
ATOM   7959 C CA  . PHE C 2 429 ? 215.443 199.965 183.612 1.00 60.30  ? 429  PHE A CA  1 
ATOM   7960 C C   . PHE C 2 429 ? 215.033 200.849 184.784 1.00 60.30  ? 429  PHE A C   1 
ATOM   7961 O O   . PHE C 2 429 ? 214.144 201.697 184.657 1.00 60.30  ? 429  PHE A O   1 
ATOM   7962 C CB  . PHE C 2 429 ? 216.233 200.776 182.586 1.00 60.30  ? 429  PHE A CB  1 
ATOM   7963 C CG  . PHE C 2 429 ? 217.345 201.591 183.182 1.00 60.30  ? 429  PHE A CG  1 
ATOM   7964 C CD1 . PHE C 2 429 ? 218.530 200.991 183.571 1.00 60.30  ? 429  PHE A CD1 1 
ATOM   7965 C CD2 . PHE C 2 429 ? 217.207 202.960 183.345 1.00 60.30  ? 429  PHE A CD2 1 
ATOM   7966 C CE1 . PHE C 2 429 ? 219.554 201.740 184.118 1.00 60.30  ? 429  PHE A CE1 1 
ATOM   7967 C CE2 . PHE C 2 429 ? 218.227 203.713 183.891 1.00 60.30  ? 429  PHE A CE2 1 
ATOM   7968 C CZ  . PHE C 2 429 ? 219.403 203.103 184.277 1.00 60.30  ? 429  PHE A CZ  1 
ATOM   7969 N N   . THR C 2 430 ? 215.685 200.648 185.926 1.00 60.23  ? 430  THR A N   1 
ATOM   7970 C CA  . THR C 2 430 ? 215.435 201.425 187.137 1.00 60.23  ? 430  THR A CA  1 
ATOM   7971 C C   . THR C 2 430 ? 216.704 202.208 187.460 1.00 60.23  ? 430  THR A C   1 
ATOM   7972 O O   . THR C 2 430 ? 217.672 201.648 187.985 1.00 60.23  ? 430  THR A O   1 
ATOM   7973 C CB  . THR C 2 430 ? 215.029 200.522 188.299 1.00 60.23  ? 430  THR A CB  1 
ATOM   7974 O OG1 . THR C 2 430 ? 213.853 199.784 187.943 1.00 60.23  ? 430  THR A OG1 1 
ATOM   7975 C CG2 . THR C 2 430 ? 214.743 201.351 189.542 1.00 60.23  ? 430  THR A CG2 1 
ATOM   7976 N N   . GLY C 2 431 ? 216.699 203.498 187.147 1.00 61.71  ? 431  GLY A N   1 
ATOM   7977 C CA  . GLY C 2 431 ? 217.855 204.329 187.407 1.00 61.71  ? 431  GLY A CA  1 
ATOM   7978 C C   . GLY C 2 431 ? 217.673 205.706 186.801 1.00 61.71  ? 431  GLY A C   1 
ATOM   7979 O O   . GLY C 2 431 ? 216.588 206.064 186.337 1.00 61.71  ? 431  GLY A O   1 
ATOM   7980 N N   . CYS C 2 432 ? 218.762 206.469 186.818 1.00 64.20  ? 432  CYS A N   1 
ATOM   7981 C CA  . CYS C 2 432 ? 218.789 207.824 186.287 1.00 64.20  ? 432  CYS A CA  1 
ATOM   7982 C C   . CYS C 2 432 ? 219.898 207.947 185.253 1.00 64.20  ? 432  CYS A C   1 
ATOM   7983 O O   . CYS C 2 432 ? 220.981 207.377 185.419 1.00 64.20  ? 432  CYS A O   1 
ATOM   7984 C CB  . CYS C 2 432 ? 219.006 208.854 187.402 1.00 64.20  ? 432  CYS A CB  1 
ATOM   7985 S SG  . CYS C 2 432 ? 217.792 208.812 188.743 1.00 64.20  ? 432  CYS A SG  1 
ATOM   7986 N N   . VAL C 2 433 ? 219.623 208.691 184.184 1.00 59.58  ? 433  VAL A N   1 
ATOM   7987 C CA  . VAL C 2 433 ? 220.609 208.996 183.154 1.00 59.58  ? 433  VAL A CA  1 
ATOM   7988 C C   . VAL C 2 433 ? 221.043 210.445 183.328 1.00 59.58  ? 433  VAL A C   1 
ATOM   7989 O O   . VAL C 2 433 ? 220.203 211.350 183.405 1.00 59.58  ? 433  VAL A O   1 
ATOM   7990 C CB  . VAL C 2 433 ? 220.056 208.741 181.740 1.00 59.58  ? 433  VAL A CB  1 
ATOM   7991 C CG1 . VAL C 2 433 ? 220.002 207.248 181.459 1.00 59.58  ? 433  VAL A CG1 1 
ATOM   7992 C CG2 . VAL C 2 433 ? 218.675 209.357 181.577 1.00 59.58  ? 433  VAL A CG2 1 
ATOM   7993 N N   . ILE C 2 434 ? 222.353 210.661 183.409 1.00 56.32  ? 434  ILE A N   1 
ATOM   7994 C CA  . ILE C 2 434 ? 222.930 211.977 183.650 1.00 56.32  ? 434  ILE A CA  1 
ATOM   7995 C C   . ILE C 2 434 ? 223.910 212.283 182.527 1.00 56.32  ? 434  ILE A C   1 
ATOM   7996 O O   . ILE C 2 434 ? 224.771 211.456 182.209 1.00 56.32  ? 434  ILE A O   1 
ATOM   7997 C CB  . ILE C 2 434 ? 223.631 212.046 185.019 1.00 56.32  ? 434  ILE A CB  1 
ATOM   7998 C CG1 . ILE C 2 434 ? 222.702 211.536 186.123 1.00 56.32  ? 434  ILE A CG1 1 
ATOM   7999 C CG2 . ILE C 2 434 ? 224.076 213.465 185.318 1.00 56.32  ? 434  ILE A CG2 1 
ATOM   8000 C CD1 . ILE C 2 434 ? 223.368 211.421 187.475 1.00 56.32  ? 434  ILE A CD1 1 
ATOM   8001 N N   . ALA C 2 435 ? 223.779 213.467 181.932 1.00 55.24  ? 435  ALA A N   1 
ATOM   8002 C CA  . ALA C 2 435 ? 224.650 213.874 180.841 1.00 55.24  ? 435  ALA A CA  1 
ATOM   8003 C C   . ALA C 2 435 ? 224.901 215.371 180.929 1.00 55.24  ? 435  ALA A C   1 
ATOM   8004 O O   . ALA C 2 435 ? 224.049 216.132 181.396 1.00 55.24  ? 435  ALA A O   1 
ATOM   8005 C CB  . ALA C 2 435 ? 224.050 213.517 179.476 1.00 55.24  ? 435  ALA A CB  1 
ATOM   8006 N N   . TRP C 2 436 ? 226.081 215.786 180.472 1.00 54.53  ? 436  TRP A N   1 
ATOM   8007 C CA  . TRP C 2 436 ? 226.449 217.193 180.468 1.00 54.53  ? 436  TRP A CA  1 
ATOM   8008 C C   . TRP C 2 436 ? 227.385 217.459 179.299 1.00 54.53  ? 436  TRP A C   1 
ATOM   8009 O O   . TRP C 2 436 ? 228.104 216.565 178.844 1.00 54.53  ? 436  TRP A O   1 
ATOM   8010 C CB  . TRP C 2 436 ? 227.111 217.610 181.788 1.00 54.53  ? 436  TRP A CB  1 
ATOM   8011 C CG  . TRP C 2 436 ? 228.435 216.955 182.039 1.00 54.53  ? 436  TRP A CG  1 
ATOM   8012 C CD1 . TRP C 2 436 ? 229.667 217.459 181.740 1.00 54.53  ? 436  TRP A CD1 1 
ATOM   8013 C CD2 . TRP C 2 436 ? 228.661 215.677 182.645 1.00 54.53  ? 436  TRP A CD2 1 
ATOM   8014 N NE1 . TRP C 2 436 ? 230.646 216.574 182.121 1.00 54.53  ? 436  TRP A NE1 1 
ATOM   8015 C CE2 . TRP C 2 436 ? 230.054 215.471 182.678 1.00 54.53  ? 436  TRP A CE2 1 
ATOM   8016 C CE3 . TRP C 2 436 ? 227.820 214.686 183.160 1.00 54.53  ? 436  TRP A CE3 1 
ATOM   8017 C CZ2 . TRP C 2 436 ? 230.625 214.316 183.208 1.00 54.53  ? 436  TRP A CZ2 1 
ATOM   8018 C CZ3 . TRP C 2 436 ? 228.389 213.541 183.685 1.00 54.53  ? 436  TRP A CZ3 1 
ATOM   8019 C CH2 . TRP C 2 436 ? 229.778 213.365 183.705 1.00 54.53  ? 436  TRP A CH2 1 
ATOM   8020 N N   . ASN C 2 437 ? 227.367 218.699 178.819 1.00 54.90  ? 437  ASN A N   1 
ATOM   8021 C CA  . ASN C 2 437 ? 228.217 219.081 177.701 1.00 54.90  ? 437  ASN A CA  1 
ATOM   8022 C C   . ASN C 2 437 ? 229.674 219.146 178.143 1.00 54.90  ? 437  ASN A C   1 
ATOM   8023 O O   . ASN C 2 437 ? 229.995 219.680 179.208 1.00 54.90  ? 437  ASN A O   1 
ATOM   8024 C CB  . ASN C 2 437 ? 227.774 220.431 177.135 1.00 54.90  ? 437  ASN A CB  1 
ATOM   8025 C CG  . ASN C 2 437 ? 228.337 220.702 175.751 1.00 54.90  ? 437  ASN A CG  1 
ATOM   8026 O OD1 . ASN C 2 437 ? 229.419 220.232 175.400 1.00 54.90  ? 437  ASN A OD1 1 
ATOM   8027 N ND2 . ASN C 2 437 ? 227.598 221.466 174.955 1.00 54.90  ? 437  ASN A ND2 1 
ATOM   8028 N N   . SER C 2 438 ? 230.558 218.600 177.313 1.00 56.01  ? 438  SER A N   1 
ATOM   8029 C CA  . SER C 2 438 ? 231.988 218.555 177.595 1.00 56.01  ? 438  SER A CA  1 
ATOM   8030 C C   . SER C 2 438 ? 232.785 219.059 176.403 1.00 56.01  ? 438  SER A C   1 
ATOM   8031 O O   . SER C 2 438 ? 233.821 218.494 176.038 1.00 56.01  ? 438  SER A O   1 
ATOM   8032 C CB  . SER C 2 438 ? 232.424 217.143 177.978 1.00 56.01  ? 438  SER A CB  1 
ATOM   8033 O OG  . SER C 2 438 ? 232.167 216.228 176.927 1.00 56.01  ? 438  SER A OG  1 
ATOM   8034 N N   . ASN C 2 439 ? 232.310 220.135 175.773 1.00 58.12  ? 439  ASN A N   1 
ATOM   8035 C CA  . ASN C 2 439 ? 233.025 220.712 174.642 1.00 58.12  ? 439  ASN A CA  1 
ATOM   8036 C C   . ASN C 2 439 ? 234.318 221.395 175.067 1.00 58.12  ? 439  ASN A C   1 
ATOM   8037 O O   . ASN C 2 439 ? 235.229 221.537 174.245 1.00 58.12  ? 439  ASN A O   1 
ATOM   8038 C CB  . ASN C 2 439 ? 232.123 221.704 173.905 1.00 58.12  ? 439  ASN A CB  1 
ATOM   8039 C CG  . ASN C 2 439 ? 232.767 222.256 172.648 1.00 58.12  ? 439  ASN A CG  1 
ATOM   8040 O OD1 . ASN C 2 439 ? 232.704 221.641 171.584 1.00 58.12  ? 439  ASN A OD1 1 
ATOM   8041 N ND2 . ASN C 2 439 ? 233.387 223.424 172.765 1.00 58.12  ? 439  ASN A ND2 1 
ATOM   8042 N N   . ASN C 2 440 ? 234.422 221.814 176.327 1.00 58.99  ? 440  ASN A N   1 
ATOM   8043 C CA  . ASN C 2 440 ? 235.627 222.470 176.816 1.00 58.99  ? 440  ASN A CA  1 
ATOM   8044 C C   . ASN C 2 440 ? 236.776 221.501 177.063 1.00 58.99  ? 440  ASN A C   1 
ATOM   8045 O O   . ASN C 2 440 ? 237.918 221.949 177.209 1.00 58.99  ? 440  ASN A O   1 
ATOM   8046 C CB  . ASN C 2 440 ? 235.320 223.236 178.105 1.00 58.99  ? 440  ASN A CB  1 
ATOM   8047 C CG  . ASN C 2 440 ? 234.226 224.269 177.923 1.00 58.99  ? 440  ASN A CG  1 
ATOM   8048 O OD1 . ASN C 2 440 ? 234.493 225.417 177.569 1.00 58.99  ? 440  ASN A OD1 1 
ATOM   8049 N ND2 . ASN C 2 440 ? 232.985 223.864 178.165 1.00 58.99  ? 440  ASN A ND2 1 
ATOM   8050 N N   . LEU C 2 441 ? 236.508 220.198 177.114 1.00 56.55  ? 441  LEU A N   1 
ATOM   8051 C CA  . LEU C 2 441 ? 237.532 219.205 177.414 1.00 56.55  ? 441  LEU A CA  1 
ATOM   8052 C C   . LEU C 2 441 ? 237.749 218.218 176.280 1.00 56.55  ? 441  LEU A C   1 
ATOM   8053 O O   . LEU C 2 441 ? 238.898 217.949 175.910 1.00 56.55  ? 441  LEU A O   1 
ATOM   8054 C CB  . LEU C 2 441 ? 237.165 218.448 178.701 1.00 56.55  ? 441  LEU A CB  1 
ATOM   8055 C CG  . LEU C 2 441 ? 236.968 219.293 179.960 1.00 56.55  ? 441  LEU A CG  1 
ATOM   8056 C CD1 . LEU C 2 441 ? 236.588 218.413 181.140 1.00 56.55  ? 441  LEU A CD1 1 
ATOM   8057 C CD2 . LEU C 2 441 ? 238.220 220.098 180.268 1.00 56.55  ? 441  LEU A CD2 1 
ATOM   8058 N N   . ASP C 2 442 ? 236.678 217.667 175.714 1.00 57.08  ? 442  ASP A N   1 
ATOM   8059 C CA  . ASP C 2 442 ? 236.776 216.615 174.712 1.00 57.08  ? 442  ASP A CA  1 
ATOM   8060 C C   . ASP C 2 442 ? 236.867 217.149 173.288 1.00 57.08  ? 442  ASP A C   1 
ATOM   8061 O O   . ASP C 2 442 ? 236.833 216.356 172.341 1.00 57.08  ? 442  ASP A O   1 
ATOM   8062 C CB  . ASP C 2 442 ? 235.582 215.665 174.832 1.00 57.08  ? 442  ASP A CB  1 
ATOM   8063 C CG  . ASP C 2 442 ? 235.471 215.041 176.208 1.00 57.08  ? 442  ASP A CG  1 
ATOM   8064 O OD1 . ASP C 2 442 ? 236.518 214.843 176.859 1.00 57.08  ? 442  ASP A OD1 1 
ATOM   8065 O OD2 . ASP C 2 442 ? 234.336 214.750 176.641 1.00 57.08  ? 442  ASP A OD2 1 
ATOM   8066 N N   . SER C 2 443 ? 236.983 218.462 173.110 1.00 56.01  ? 443  SER A N   1 
ATOM   8067 C CA  . SER C 2 443 ? 237.085 219.068 171.791 1.00 56.01  ? 443  SER A CA  1 
ATOM   8068 C C   . SER C 2 443 ? 238.400 219.824 171.669 1.00 56.01  ? 443  SER A C   1 
ATOM   8069 O O   . SER C 2 443 ? 238.797 220.551 172.585 1.00 56.01  ? 443  SER A O   1 
ATOM   8070 C CB  . SER C 2 443 ? 235.912 220.016 171.521 1.00 56.01  ? 443  SER A CB  1 
ATOM   8071 O OG  . SER C 2 443 ? 234.677 219.324 171.560 1.00 56.01  ? 443  SER A OG  1 
ATOM   8072 N N   . LYS C 2 444 ? 239.071 219.646 170.534 1.00 56.66  ? 444  LYS A N   1 
ATOM   8073 C CA  . LYS C 2 444 ? 240.325 220.327 170.256 1.00 56.66  ? 444  LYS A CA  1 
ATOM   8074 C C   . LYS C 2 444 ? 240.354 220.745 168.794 1.00 56.66  ? 444  LYS A C   1 
ATOM   8075 O O   . LYS C 2 444 ? 239.691 220.140 167.947 1.00 56.66  ? 444  LYS A O   1 
ATOM   8076 C CB  . LYS C 2 444 ? 241.536 219.439 170.576 1.00 56.66  ? 444  LYS A CB  1 
ATOM   8077 C CG  . LYS C 2 444 ? 241.599 218.156 169.764 1.00 56.66  ? 444  LYS A CG  1 
ATOM   8078 C CD  . LYS C 2 444 ? 242.816 217.326 170.137 1.00 56.66  ? 444  LYS A CD  1 
ATOM   8079 C CE  . LYS C 2 444 ? 244.105 218.088 169.880 1.00 56.66  ? 444  LYS A CE  1 
ATOM   8080 N NZ  . LYS C 2 444 ? 244.255 218.455 168.445 1.00 56.66  ? 444  LYS A NZ  1 
ATOM   8081 N N   . VAL C 2 445 ? 241.129 221.790 168.508 1.00 57.82  ? 445  VAL A N   1 
ATOM   8082 C CA  . VAL C 2 445 ? 241.237 222.294 167.145 1.00 57.82  ? 445  VAL A CA  1 
ATOM   8083 C C   . VAL C 2 445 ? 241.936 221.258 166.276 1.00 57.82  ? 445  VAL A C   1 
ATOM   8084 O O   . VAL C 2 445 ? 242.972 220.697 166.656 1.00 57.82  ? 445  VAL A O   1 
ATOM   8085 C CB  . VAL C 2 445 ? 241.974 223.643 167.127 1.00 57.82  ? 445  VAL A CB  1 
ATOM   8086 C CG1 . VAL C 2 445 ? 243.268 223.561 167.927 1.00 57.82  ? 445  VAL A CG1 1 
ATOM   8087 C CG2 . VAL C 2 445 ? 242.250 224.085 165.697 1.00 57.82  ? 445  VAL A CG2 1 
ATOM   8088 N N   . GLY C 2 446 ? 241.361 220.987 165.105 1.00 56.56  ? 446  GLY A N   1 
ATOM   8089 C CA  . GLY C 2 446 ? 241.880 220.003 164.186 1.00 56.56  ? 446  GLY A CA  1 
ATOM   8090 C C   . GLY C 2 446 ? 241.148 218.677 164.203 1.00 56.56  ? 446  GLY A C   1 
ATOM   8091 O O   . GLY C 2 446 ? 241.316 217.881 163.272 1.00 56.56  ? 446  GLY A O   1 
ATOM   8092 N N   . GLY C 2 447 ? 240.343 218.420 165.231 1.00 57.36  ? 447  GLY A N   1 
ATOM   8093 C CA  . GLY C 2 447 ? 239.589 217.186 165.311 1.00 57.36  ? 447  GLY A CA  1 
ATOM   8094 C C   . GLY C 2 447 ? 240.082 216.243 166.388 1.00 57.36  ? 447  GLY A C   1 
ATOM   8095 O O   . GLY C 2 447 ? 241.241 215.818 166.370 1.00 57.36  ? 447  GLY A O   1 
ATOM   8096 N N   . ASN C 2 448 ? 239.208 215.910 167.335 1.00 55.65  ? 448  ASN A N   1 
ATOM   8097 C CA  . ASN C 2 448 ? 239.524 214.978 168.415 1.00 55.65  ? 448  ASN A CA  1 
ATOM   8098 C C   . ASN C 2 448 ? 238.951 213.617 168.038 1.00 55.65  ? 448  ASN A C   1 
ATOM   8099 O O   . ASN C 2 448 ? 237.771 213.341 168.270 1.00 55.65  ? 448  ASN A O   1 
ATOM   8100 C CB  . ASN C 2 448 ? 238.964 215.477 169.743 1.00 55.65  ? 448  ASN A CB  1 
ATOM   8101 C CG  . ASN C 2 448 ? 239.323 214.571 170.904 1.00 55.65  ? 448  ASN A CG  1 
ATOM   8102 O OD1 . ASN C 2 448 ? 240.299 213.825 170.845 1.00 55.65  ? 448  ASN A OD1 1 
ATOM   8103 N ND2 . ASN C 2 448 ? 238.531 214.632 171.968 1.00 55.65  ? 448  ASN A ND2 1 
ATOM   8104 N N   . TYR C 2 449 ? 239.792 212.764 167.453 1.00 55.03  ? 449  TYR A N   1 
ATOM   8105 C CA  . TYR C 2 449 ? 239.381 211.448 166.979 1.00 55.03  ? 449  TYR A CA  1 
ATOM   8106 C C   . TYR C 2 449 ? 239.725 210.338 167.968 1.00 55.03  ? 449  TYR A C   1 
ATOM   8107 O O   . TYR C 2 449 ? 240.026 209.213 167.557 1.00 55.03  ? 449  TYR A O   1 
ATOM   8108 C CB  . TYR C 2 449 ? 240.011 211.156 165.618 1.00 55.03  ? 449  TYR A CB  1 
ATOM   8109 C CG  . TYR C 2 449 ? 239.635 212.144 164.538 1.00 55.03  ? 449  TYR A CG  1 
ATOM   8110 C CD1 . TYR C 2 449 ? 238.462 211.994 163.811 1.00 55.03  ? 449  TYR A CD1 1 
ATOM   8111 C CD2 . TYR C 2 449 ? 240.456 213.224 164.241 1.00 55.03  ? 449  TYR A CD2 1 
ATOM   8112 C CE1 . TYR C 2 449 ? 238.115 212.893 162.821 1.00 55.03  ? 449  TYR A CE1 1 
ATOM   8113 C CE2 . TYR C 2 449 ? 240.117 214.128 163.253 1.00 55.03  ? 449  TYR A CE2 1 
ATOM   8114 C CZ  . TYR C 2 449 ? 238.946 213.958 162.547 1.00 55.03  ? 449  TYR A CZ  1 
ATOM   8115 O OH  . TYR C 2 449 ? 238.604 214.855 161.562 1.00 55.03  ? 449  TYR A OH  1 
ATOM   8116 N N   . ASN C 2 450 ? 239.687 210.632 169.267 1.00 56.95  ? 450  ASN A N   1 
ATOM   8117 C CA  . ASN C 2 450 ? 240.011 209.636 170.279 1.00 56.95  ? 450  ASN A CA  1 
ATOM   8118 C C   . ASN C 2 450 ? 238.816 208.790 170.696 1.00 56.95  ? 450  ASN A C   1 
ATOM   8119 O O   . ASN C 2 450 ? 239.010 207.709 171.263 1.00 56.95  ? 450  ASN A O   1 
ATOM   8120 C CB  . ASN C 2 450 ? 240.605 210.314 171.518 1.00 56.95  ? 450  ASN A CB  1 
ATOM   8121 C CG  . ASN C 2 450 ? 241.965 210.926 171.250 1.00 56.95  ? 450  ASN A CG  1 
ATOM   8122 O OD1 . ASN C 2 450 ? 242.996 210.279 171.431 1.00 56.95  ? 450  ASN A OD1 1 
ATOM   8123 N ND2 . ASN C 2 450 ? 241.974 212.181 170.816 1.00 56.95  ? 450  ASN A ND2 1 
ATOM   8124 N N   . TYR C 2 451 ? 237.596 209.248 170.433 1.00 55.34  ? 451  TYR A N   1 
ATOM   8125 C CA  . TYR C 2 451 ? 236.392 208.519 170.801 1.00 55.34  ? 451  TYR A CA  1 
ATOM   8126 C C   . TYR C 2 451 ? 235.798 207.841 169.574 1.00 55.34  ? 451  TYR A C   1 
ATOM   8127 O O   . TYR C 2 451 ? 235.748 208.428 168.489 1.00 55.34  ? 451  TYR A O   1 
ATOM   8128 C CB  . TYR C 2 451 ? 235.363 209.455 171.438 1.00 55.34  ? 451  TYR A CB  1 
ATOM   8129 C CG  . TYR C 2 451 ? 235.891 210.199 172.643 1.00 55.34  ? 451  TYR A CG  1 
ATOM   8130 C CD1 . TYR C 2 451 ? 235.894 209.610 173.900 1.00 55.34  ? 451  TYR A CD1 1 
ATOM   8131 C CD2 . TYR C 2 451 ? 236.392 211.488 172.523 1.00 55.34  ? 451  TYR A CD2 1 
ATOM   8132 C CE1 . TYR C 2 451 ? 236.378 210.284 175.004 1.00 55.34  ? 451  TYR A CE1 1 
ATOM   8133 C CE2 . TYR C 2 451 ? 236.878 212.171 173.622 1.00 55.34  ? 451  TYR A CE2 1 
ATOM   8134 C CZ  . TYR C 2 451 ? 236.868 211.564 174.859 1.00 55.34  ? 451  TYR A CZ  1 
ATOM   8135 O OH  . TYR C 2 451 ? 237.351 212.240 175.956 1.00 55.34  ? 451  TYR A OH  1 
ATOM   8136 N N   . LEU C 2 452 ? 235.347 206.602 169.752 1.00 55.01  ? 452  LEU A N   1 
ATOM   8137 C CA  . LEU C 2 452 ? 234.824 205.797 168.659 1.00 55.01  ? 452  LEU A CA  1 
ATOM   8138 C C   . LEU C 2 452 ? 233.457 205.241 169.032 1.00 55.01  ? 452  LEU A C   1 
ATOM   8139 O O   . LEU C 2 452 ? 233.072 205.209 170.203 1.00 55.01  ? 452  LEU A O   1 
ATOM   8140 C CB  . LEU C 2 452 ? 235.773 204.642 168.297 1.00 55.01  ? 452  LEU A CB  1 
ATOM   8141 C CG  . LEU C 2 452 ? 237.157 204.977 167.733 1.00 55.01  ? 452  LEU A CG  1 
ATOM   8142 C CD1 . LEU C 2 452 ? 238.151 205.308 168.838 1.00 55.01  ? 452  LEU A CD1 1 
ATOM   8143 C CD2 . LEU C 2 452 ? 237.673 203.833 166.873 1.00 55.01  ? 452  LEU A CD2 1 
ATOM   8144 N N   . TYR C 2 453 ? 232.724 204.801 168.012 1.00 55.89  ? 453  TYR A N   1 
ATOM   8145 C CA  . TYR C 2 453 ? 231.416 204.195 168.210 1.00 55.89  ? 453  TYR A CA  1 
ATOM   8146 C C   . TYR C 2 453 ? 231.218 203.098 167.175 1.00 55.89  ? 453  TYR A C   1 
ATOM   8147 O O   . TYR C 2 453 ? 231.684 203.206 166.038 1.00 55.89  ? 453  TYR A O   1 
ATOM   8148 C CB  . TYR C 2 453 ? 230.287 205.230 168.119 1.00 55.89  ? 453  TYR A CB  1 
ATOM   8149 C CG  . TYR C 2 453 ? 230.038 205.778 166.731 1.00 55.89  ? 453  TYR A CG  1 
ATOM   8150 C CD1 . TYR C 2 453 ? 230.856 206.764 166.195 1.00 55.89  ? 453  TYR A CD1 1 
ATOM   8151 C CD2 . TYR C 2 453 ? 228.975 205.321 165.964 1.00 55.89  ? 453  TYR A CD2 1 
ATOM   8152 C CE1 . TYR C 2 453 ? 230.628 207.270 164.930 1.00 55.89  ? 453  TYR A CE1 1 
ATOM   8153 C CE2 . TYR C 2 453 ? 228.739 205.822 164.699 1.00 55.89  ? 453  TYR A CE2 1 
ATOM   8154 C CZ  . TYR C 2 453 ? 229.568 206.797 164.187 1.00 55.89  ? 453  TYR A CZ  1 
ATOM   8155 O OH  . TYR C 2 453 ? 229.337 207.298 162.927 1.00 55.89  ? 453  TYR A OH  1 
ATOM   8156 N N   . ARG C 2 454 ? 230.524 202.039 167.584 1.00 56.39  ? 454  ARG A N   1 
ATOM   8157 C CA  . ARG C 2 454 ? 230.256 200.915 166.697 1.00 56.39  ? 454  ARG A CA  1 
ATOM   8158 C C   . ARG C 2 454 ? 229.111 201.272 165.757 1.00 56.39  ? 454  ARG A C   1 
ATOM   8159 O O   . ARG C 2 454 ? 227.993 201.547 166.205 1.00 56.39  ? 454  ARG A O   1 
ATOM   8160 C CB  . ARG C 2 454 ? 229.925 199.663 167.505 1.00 56.39  ? 454  ARG A CB  1 
ATOM   8161 C CG  . ARG C 2 454 ? 229.673 198.428 166.657 1.00 56.39  ? 454  ARG A CG  1 
ATOM   8162 C CD  . ARG C 2 454 ? 229.520 197.189 167.520 1.00 56.39  ? 454  ARG A CD  1 
ATOM   8163 N NE  . ARG C 2 454 ? 230.711 196.940 168.326 1.00 56.39  ? 454  ARG A NE  1 
ATOM   8164 C CZ  . ARG C 2 454 ? 231.762 196.242 167.910 1.00 56.39  ? 454  ARG A CZ  1 
ATOM   8165 N NH1 . ARG C 2 454 ? 232.803 196.066 168.712 1.00 56.39  ? 454  ARG A NH1 1 
ATOM   8166 N NH2 . ARG C 2 454 ? 231.773 195.720 166.691 1.00 56.39  ? 454  ARG A NH2 1 
ATOM   8167 N N   . LEU C 2 455 ? 229.391 201.266 164.455 1.00 55.78  ? 455  LEU A N   1 
ATOM   8168 C CA  . LEU C 2 455 ? 228.411 201.651 163.448 1.00 55.78  ? 455  LEU A CA  1 
ATOM   8169 C C   . LEU C 2 455 ? 227.697 200.465 162.817 1.00 55.78  ? 455  LEU A C   1 
ATOM   8170 O O   . LEU C 2 455 ? 226.518 200.581 162.469 1.00 55.78  ? 455  LEU A O   1 
ATOM   8171 C CB  . LEU C 2 455 ? 229.088 202.477 162.348 1.00 55.78  ? 455  LEU A CB  1 
ATOM   8172 C CG  . LEU C 2 455 ? 228.196 203.124 161.287 1.00 55.78  ? 455  LEU A CG  1 
ATOM   8173 C CD1 . LEU C 2 455 ? 227.199 204.073 161.928 1.00 55.78  ? 455  LEU A CD1 1 
ATOM   8174 C CD2 . LEU C 2 455 ? 229.041 203.852 160.255 1.00 55.78  ? 455  LEU A CD2 1 
ATOM   8175 N N   . PHE C 2 456 ? 228.373 199.329 162.668 1.00 56.97  ? 456  PHE A N   1 
ATOM   8176 C CA  . PHE C 2 456 ? 227.810 198.152 162.025 1.00 56.97  ? 456  PHE A CA  1 
ATOM   8177 C C   . PHE C 2 456 ? 227.908 196.952 162.956 1.00 56.97  ? 456  PHE A C   1 
ATOM   8178 O O   . PHE C 2 456 ? 228.925 196.759 163.629 1.00 56.97  ? 456  PHE A O   1 
ATOM   8179 C CB  . PHE C 2 456 ? 228.532 197.846 160.708 1.00 56.97  ? 456  PHE A CB  1 
ATOM   8180 C CG  . PHE C 2 456 ? 228.539 198.993 159.740 1.00 56.97  ? 456  PHE A CG  1 
ATOM   8181 C CD1 . PHE C 2 456 ? 227.397 199.747 159.528 1.00 56.97  ? 456  PHE A CD1 1 
ATOM   8182 C CD2 . PHE C 2 456 ? 229.692 199.323 159.047 1.00 56.97  ? 456  PHE A CD2 1 
ATOM   8183 C CE1 . PHE C 2 456 ? 227.403 200.805 158.639 1.00 56.97  ? 456  PHE A CE1 1 
ATOM   8184 C CE2 . PHE C 2 456 ? 229.704 200.380 158.157 1.00 56.97  ? 456  PHE A CE2 1 
ATOM   8185 C CZ  . PHE C 2 456 ? 228.558 201.121 157.953 1.00 56.97  ? 456  PHE A CZ  1 
ATOM   8186 N N   . ARG C 2 457 ? 226.847 196.149 162.989 1.00 58.67  ? 457  ARG A N   1 
ATOM   8187 C CA  . ARG C 2 457 ? 226.841 194.921 163.771 1.00 58.67  ? 457  ARG A CA  1 
ATOM   8188 C C   . ARG C 2 457 ? 225.791 193.983 163.196 1.00 58.67  ? 457  ARG A C   1 
ATOM   8189 O O   . ARG C 2 457 ? 224.787 194.425 162.632 1.00 58.67  ? 457  ARG A O   1 
ATOM   8190 C CB  . ARG C 2 457 ? 226.566 195.195 165.255 1.00 58.67  ? 457  ARG A CB  1 
ATOM   8191 C CG  . ARG C 2 457 ? 226.956 194.047 166.172 1.00 58.67  ? 457  ARG A CG  1 
ATOM   8192 C CD  . ARG C 2 457 ? 226.679 194.371 167.629 1.00 58.67  ? 457  ARG A CD  1 
ATOM   8193 N NE  . ARG C 2 457 ? 227.163 193.318 168.517 1.00 58.67  ? 457  ARG A NE  1 
ATOM   8194 C CZ  . ARG C 2 457 ? 226.469 192.229 168.832 1.00 58.67  ? 457  ARG A CZ  1 
ATOM   8195 N NH1 . ARG C 2 457 ? 226.988 191.324 169.648 1.00 58.67  ? 457  ARG A NH1 1 
ATOM   8196 N NH2 . ARG C 2 457 ? 225.255 192.046 168.331 1.00 58.67  ? 457  ARG A NH2 1 
ATOM   8197 N N   . LYS C 2 458 ? 226.037 192.679 163.345 1.00 61.17  ? 458  LYS A N   1 
ATOM   8198 C CA  . LYS C 2 458 ? 225.148 191.678 162.768 1.00 61.17  ? 458  LYS A CA  1 
ATOM   8199 C C   . LYS C 2 458 ? 223.806 191.601 163.482 1.00 61.17  ? 458  LYS A C   1 
ATOM   8200 O O   . LYS C 2 458 ? 222.824 191.155 162.879 1.00 61.17  ? 458  LYS A O   1 
ATOM   8201 C CB  . LYS C 2 458 ? 225.822 190.305 162.785 1.00 61.17  ? 458  LYS A CB  1 
ATOM   8202 C CG  . LYS C 2 458 ? 227.121 190.242 162.001 1.00 61.17  ? 458  LYS A CG  1 
ATOM   8203 C CD  . LYS C 2 458 ? 227.738 188.855 162.067 1.00 61.17  ? 458  LYS A CD  1 
ATOM   8204 C CE  . LYS C 2 458 ? 229.041 188.794 161.288 1.00 61.17  ? 458  LYS A CE  1 
ATOM   8205 N NZ  . LYS C 2 458 ? 228.843 189.126 159.850 1.00 61.17  ? 458  LYS A NZ  1 
ATOM   8206 N N   . SER C 2 459 ? 223.736 192.021 164.743 1.00 59.04  ? 459  SER A N   1 
ATOM   8207 C CA  . SER C 2 459 ? 222.491 191.957 165.493 1.00 59.04  ? 459  SER A CA  1 
ATOM   8208 C C   . SER C 2 459 ? 222.534 192.988 166.611 1.00 59.04  ? 459  SER A C   1 
ATOM   8209 O O   . SER C 2 459 ? 223.598 193.504 166.964 1.00 59.04  ? 459  SER A O   1 
ATOM   8210 C CB  . SER C 2 459 ? 222.247 190.555 166.061 1.00 59.04  ? 459  SER A CB  1 
ATOM   8211 O OG  . SER C 2 459 ? 223.293 190.172 166.937 1.00 59.04  ? 459  SER A OG  1 
ATOM   8212 N N   . ASN C 2 460 ? 221.359 193.281 167.159 1.00 57.70  ? 460  ASN A N   1 
ATOM   8213 C CA  . ASN C 2 460 ? 221.258 194.238 168.248 1.00 57.70  ? 460  ASN A CA  1 
ATOM   8214 C C   . ASN C 2 460 ? 221.889 193.675 169.519 1.00 57.70  ? 460  ASN A C   1 
ATOM   8215 O O   . ASN C 2 460 ? 222.045 192.463 169.687 1.00 57.70  ? 460  ASN A O   1 
ATOM   8216 C CB  . ASN C 2 460 ? 219.798 194.608 168.506 1.00 57.70  ? 460  ASN A CB  1 
ATOM   8217 C CG  . ASN C 2 460 ? 219.144 195.270 167.311 1.00 57.70  ? 460  ASN A CG  1 
ATOM   8218 O OD1 . ASN C 2 460 ? 219.626 195.158 166.184 1.00 57.70  ? 460  ASN A OD1 1 
ATOM   8219 N ND2 . ASN C 2 460 ? 218.040 195.966 167.551 1.00 57.70  ? 460  ASN A ND2 1 
ATOM   8220 N N   . LEU C 2 461 ? 222.253 194.580 170.420 1.00 58.29  ? 461  LEU A N   1 
ATOM   8221 C CA  . LEU C 2 461 ? 222.872 194.204 171.681 1.00 58.29  ? 461  LEU A CA  1 
ATOM   8222 C C   . LEU C 2 461 ? 221.816 193.895 172.733 1.00 58.29  ? 461  LEU A C   1 
ATOM   8223 O O   . LEU C 2 461 ? 220.710 194.442 172.714 1.00 58.29  ? 461  LEU A O   1 
ATOM   8224 C CB  . LEU C 2 461 ? 223.791 195.316 172.190 1.00 58.29  ? 461  LEU A CB  1 
ATOM   8225 C CG  . LEU C 2 461 ? 225.161 195.458 171.528 1.00 58.29  ? 461  LEU A CG  1 
ATOM   8226 C CD1 . LEU C 2 461 ? 225.934 196.600 172.161 1.00 58.29  ? 461  LEU A CD1 1 
ATOM   8227 C CD2 . LEU C 2 461 ? 225.940 194.160 171.642 1.00 58.29  ? 461  LEU A CD2 1 
ATOM   8228 N N   . LYS C 2 462 ? 222.172 193.008 173.653 1.00 61.10  ? 462  LYS A N   1 
ATOM   8229 C CA  . LYS C 2 462 ? 221.335 192.729 174.804 1.00 61.10  ? 462  LYS A CA  1 
ATOM   8230 C C   . LYS C 2 462 ? 221.497 193.835 175.841 1.00 61.10  ? 462  LYS A C   1 
ATOM   8231 O O   . LYS C 2 462 ? 222.498 194.556 175.839 1.00 61.10  ? 462  LYS A O   1 
ATOM   8232 C CB  . LYS C 2 462 ? 221.705 191.376 175.405 1.00 61.10  ? 462  LYS A CB  1 
ATOM   8233 C CG  . LYS C 2 462 ? 221.605 190.214 174.431 1.00 61.10  ? 462  LYS A CG  1 
ATOM   8234 C CD  . LYS C 2 462 ? 220.179 190.023 173.940 1.00 61.10  ? 462  LYS A CD  1 
ATOM   8235 C CE  . LYS C 2 462 ? 219.246 189.666 175.085 1.00 61.10  ? 462  LYS A CE  1 
ATOM   8236 N NZ  . LYS C 2 462 ? 219.658 188.406 175.762 1.00 61.10  ? 462  LYS A NZ  1 
ATOM   8237 N N   . PRO C 2 463 ? 220.513 194.009 176.723 1.00 59.80  ? 463  PRO A N   1 
ATOM   8238 C CA  . PRO C 2 463 ? 220.642 195.026 177.775 1.00 59.80  ? 463  PRO A CA  1 
ATOM   8239 C C   . PRO C 2 463 ? 221.880 194.788 178.628 1.00 59.80  ? 463  PRO A C   1 
ATOM   8240 O O   . PRO C 2 463 ? 222.112 193.683 179.124 1.00 59.80  ? 463  PRO A O   1 
ATOM   8241 C CB  . PRO C 2 463 ? 219.353 194.859 178.585 1.00 59.80  ? 463  PRO A CB  1 
ATOM   8242 C CG  . PRO C 2 463 ? 218.376 194.301 177.610 1.00 59.80  ? 463  PRO A CG  1 
ATOM   8243 C CD  . PRO C 2 463 ? 219.172 193.398 176.710 1.00 59.80  ? 463  PRO A CD  1 
ATOM   8244 N N   . PHE C 2 464 ? 222.680 195.844 178.788 1.00 59.41  ? 464  PHE A N   1 
ATOM   8245 C CA  . PHE C 2 464 ? 223.924 195.809 179.559 1.00 59.41  ? 464  PHE A CA  1 
ATOM   8246 C C   . PHE C 2 464 ? 224.889 194.763 178.996 1.00 59.41  ? 464  PHE A C   1 
ATOM   8247 O O   . PHE C 2 464 ? 225.252 193.786 179.656 1.00 59.41  ? 464  PHE A O   1 
ATOM   8248 C CB  . PHE C 2 464 ? 223.641 195.561 181.045 1.00 59.41  ? 464  PHE A CB  1 
ATOM   8249 C CG  . PHE C 2 464 ? 222.787 196.617 181.685 1.00 59.41  ? 464  PHE A CG  1 
ATOM   8250 C CD1 . PHE C 2 464 ? 222.802 197.920 181.216 1.00 59.41  ? 464  PHE A CD1 1 
ATOM   8251 C CD2 . PHE C 2 464 ? 221.965 196.306 182.755 1.00 59.41  ? 464  PHE A CD2 1 
ATOM   8252 C CE1 . PHE C 2 464 ? 222.016 198.892 181.803 1.00 59.41  ? 464  PHE A CE1 1 
ATOM   8253 C CE2 . PHE C 2 464 ? 221.176 197.274 183.346 1.00 59.41  ? 464  PHE A CE2 1 
ATOM   8254 C CZ  . PHE C 2 464 ? 221.202 198.569 182.869 1.00 59.41  ? 464  PHE A CZ  1 
ATOM   8255 N N   . GLU C 2 465 ? 225.303 194.988 177.751 1.00 60.18  ? 465  GLU A N   1 
ATOM   8256 C CA  . GLU C 2 465 ? 226.231 194.098 177.066 1.00 60.18  ? 465  GLU A CA  1 
ATOM   8257 C C   . GLU C 2 465 ? 227.296 194.925 176.364 1.00 60.18  ? 465  GLU A C   1 
ATOM   8258 O O   . GLU C 2 465 ? 226.978 195.916 175.700 1.00 60.18  ? 465  GLU A O   1 
ATOM   8259 C CB  . GLU C 2 465 ? 225.503 193.208 176.053 1.00 60.18  ? 465  GLU A CB  1 
ATOM   8260 C CG  . GLU C 2 465 ? 226.418 192.266 175.286 1.00 60.18  ? 465  GLU A CG  1 
ATOM   8261 C CD  . GLU C 2 465 ? 225.701 191.538 174.167 1.00 60.18  ? 465  GLU A CD  1 
ATOM   8262 O OE1 . GLU C 2 465 ? 224.530 191.874 173.893 1.00 60.18  ? 465  GLU A OE1 1 
ATOM   8263 O OE2 . GLU C 2 465 ? 226.308 190.632 173.561 1.00 60.18  ? 465  GLU A OE2 1 
ATOM   8264 N N   . ARG C 2 466 ? 228.552 194.517 176.511 1.00 58.91  ? 466  ARG A N   1 
ATOM   8265 C CA  . ARG C 2 466 ? 229.672 195.160 175.841 1.00 58.91  ? 466  ARG A CA  1 
ATOM   8266 C C   . ARG C 2 466 ? 230.074 194.367 174.603 1.00 58.91  ? 466  ARG A C   1 
ATOM   8267 O O   . ARG C 2 466 ? 229.808 193.169 174.487 1.00 58.91  ? 466  ARG A O   1 
ATOM   8268 C CB  . ARG C 2 466 ? 230.868 195.298 176.787 1.00 58.91  ? 466  ARG A CB  1 
ATOM   8269 C CG  . ARG C 2 466 ? 230.604 196.172 177.999 1.00 58.91  ? 466  ARG A CG  1 
ATOM   8270 C CD  . ARG C 2 466 ? 231.857 196.344 178.839 1.00 58.91  ? 466  ARG A CD  1 
ATOM   8271 N NE  . ARG C 2 466 ? 232.946 196.948 178.076 1.00 58.91  ? 466  ARG A NE  1 
ATOM   8272 C CZ  . ARG C 2 466 ? 234.133 197.257 178.587 1.00 58.91  ? 466  ARG A CZ  1 
ATOM   8273 N NH1 . ARG C 2 466 ? 235.065 197.803 177.819 1.00 58.91  ? 466  ARG A NH1 1 
ATOM   8274 N NH2 . ARG C 2 466 ? 234.388 197.022 179.866 1.00 58.91  ? 466  ARG A NH2 1 
ATOM   8275 N N   . ASP C 2 467 ? 230.729 195.060 173.671 1.00 59.47  ? 467  ASP A N   1 
ATOM   8276 C CA  . ASP C 2 467 ? 231.163 194.436 172.421 1.00 59.47  ? 467  ASP A CA  1 
ATOM   8277 C C   . ASP C 2 467 ? 232.451 195.129 171.986 1.00 59.47  ? 467  ASP A C   1 
ATOM   8278 O O   . ASP C 2 467 ? 232.407 196.210 171.393 1.00 59.47  ? 467  ASP A O   1 
ATOM   8279 C CB  . ASP C 2 467 ? 230.083 194.537 171.353 1.00 59.47  ? 467  ASP A CB  1 
ATOM   8280 C CG  . ASP C 2 467 ? 230.397 193.707 170.124 1.00 59.47  ? 467  ASP A CG  1 
ATOM   8281 O OD1 . ASP C 2 467 ? 231.394 192.954 170.149 1.00 59.47  ? 467  ASP A OD1 1 
ATOM   8282 O OD2 . ASP C 2 467 ? 229.646 193.806 169.131 1.00 59.47  ? 467  ASP A OD2 1 
ATOM   8283 N N   . ILE C 2 468 ? 233.585 194.502 172.282 1.00 58.41  ? 468  ILE A N   1 
ATOM   8284 C CA  . ILE C 2 468 ? 234.888 195.034 171.909 1.00 58.41  ? 468  ILE A CA  1 
ATOM   8285 C C   . ILE C 2 468 ? 235.458 194.303 170.691 1.00 58.41  ? 468  ILE A C   1 
ATOM   8286 O O   . ILE C 2 468 ? 236.668 194.312 170.471 1.00 58.41  ? 468  ILE A O   1 
ATOM   8287 C CB  . ILE C 2 468 ? 235.868 194.997 173.093 1.00 58.41  ? 468  ILE A CB  1 
ATOM   8288 C CG1 . ILE C 2 468 ? 235.117 195.159 174.416 1.00 58.41  ? 468  ILE A CG1 1 
ATOM   8289 C CG2 . ILE C 2 468 ? 236.904 196.107 172.969 1.00 58.41  ? 468  ILE A CG2 1 
ATOM   8290 C CD1 . ILE C 2 468 ? 234.550 196.548 174.638 1.00 58.41  ? 468  ILE A CD1 1 
ATOM   8291 N N   . SER C 2 469 ? 234.602 193.666 169.897 1.00 57.90  ? 469  SER A N   1 
ATOM   8292 C CA  . SER C 2 469 ? 235.067 192.930 168.731 1.00 57.90  ? 469  SER A CA  1 
ATOM   8293 C C   . SER C 2 469 ? 235.494 193.887 167.625 1.00 57.90  ? 469  SER A C   1 
ATOM   8294 O O   . SER C 2 469 ? 234.840 194.901 167.370 1.00 57.90  ? 469  SER A O   1 
ATOM   8295 C CB  . SER C 2 469 ? 233.971 191.996 168.220 1.00 57.90  ? 469  SER A CB  1 
ATOM   8296 O OG  . SER C 2 469 ? 233.581 191.071 169.221 1.00 57.90  ? 469  SER A OG  1 
ATOM   8297 N N   . THR C 2 470 ? 236.605 193.556 166.966 1.00 60.30  ? 470  THR A N   1 
ATOM   8298 C CA  . THR C 2 470 ? 237.123 194.341 165.853 1.00 60.30  ? 470  THR A CA  1 
ATOM   8299 C C   . THR C 2 470 ? 237.072 193.574 164.537 1.00 60.30  ? 470  THR A C   1 
ATOM   8300 O O   . THR C 2 470 ? 237.848 193.866 163.621 1.00 60.30  ? 470  THR A O   1 
ATOM   8301 C CB  . THR C 2 470 ? 238.553 194.800 166.141 1.00 60.30  ? 470  THR A CB  1 
ATOM   8302 O OG1 . THR C 2 470 ? 239.395 193.657 166.333 1.00 60.30  ? 470  THR A OG1 1 
ATOM   8303 C CG2 . THR C 2 470 ? 238.592 195.668 167.390 1.00 60.30  ? 470  THR A CG2 1 
ATOM   8304 N N   . GLU C 2 471 ? 236.177 192.597 164.426 1.00 62.94  ? 471  GLU A N   1 
ATOM   8305 C CA  . GLU C 2 471 ? 236.063 191.821 163.200 1.00 62.94  ? 471  GLU A CA  1 
ATOM   8306 C C   . GLU C 2 471 ? 235.442 192.661 162.092 1.00 62.94  ? 471  GLU A C   1 
ATOM   8307 O O   . GLU C 2 471 ? 234.557 193.486 162.336 1.00 62.94  ? 471  GLU A O   1 
ATOM   8308 C CB  . GLU C 2 471 ? 235.225 190.566 163.441 1.00 62.94  ? 471  GLU A CB  1 
ATOM   8309 C CG  . GLU C 2 471 ? 235.794 189.633 164.495 1.00 62.94  ? 471  GLU A CG  1 
ATOM   8310 C CD  . GLU C 2 471 ? 234.937 188.401 164.705 1.00 62.94  ? 471  GLU A CD  1 
ATOM   8311 O OE1 . GLU C 2 471 ? 233.892 188.281 164.032 1.00 62.94  ? 471  GLU A OE1 1 
ATOM   8312 O OE2 . GLU C 2 471 ? 235.307 187.552 165.543 1.00 62.94  ? 471  GLU A OE2 1 
ATOM   8313 N N   . ILE C 2 472 ? 235.915 192.446 160.864 1.00 60.47  ? 472  ILE A N   1 
ATOM   8314 C CA  . ILE C 2 472 ? 235.398 193.185 159.720 1.00 60.47  ? 472  ILE A CA  1 
ATOM   8315 C C   . ILE C 2 472 ? 233.954 192.775 159.466 1.00 60.47  ? 472  ILE A C   1 
ATOM   8316 O O   . ILE C 2 472 ? 233.640 191.584 159.342 1.00 60.47  ? 472  ILE A O   1 
ATOM   8317 C CB  . ILE C 2 472 ? 236.276 192.950 158.481 1.00 60.47  ? 472  ILE A CB  1 
ATOM   8318 C CG1 . ILE C 2 472 ? 237.517 193.849 158.513 1.00 60.47  ? 472  ILE A CG1 1 
ATOM   8319 C CG2 . ILE C 2 472 ? 235.484 193.195 157.206 1.00 60.47  ? 472  ILE A CG2 1 
ATOM   8320 C CD1 . ILE C 2 472 ? 238.612 193.380 159.449 1.00 60.47  ? 472  ILE A CD1 1 
ATOM   8321 N N   . TYR C 2 473 ? 233.065 193.764 159.397 1.00 60.71  ? 473  TYR A N   1 
ATOM   8322 C CA  . TYR C 2 473 ? 231.642 193.509 159.197 1.00 60.71  ? 473  TYR A CA  1 
ATOM   8323 C C   . TYR C 2 473 ? 231.403 193.038 157.769 1.00 60.71  ? 473  TYR A C   1 
ATOM   8324 O O   . TYR C 2 473 ? 231.598 193.797 156.814 1.00 60.71  ? 473  TYR A O   1 
ATOM   8325 C CB  . TYR C 2 473 ? 230.836 194.768 159.503 1.00 60.71  ? 473  TYR A CB  1 
ATOM   8326 C CG  . TYR C 2 473 ? 229.344 194.603 159.326 1.00 60.71  ? 473  TYR A CG  1 
ATOM   8327 C CD1 . TYR C 2 473 ? 228.576 193.974 160.297 1.00 60.71  ? 473  TYR A CD1 1 
ATOM   8328 C CD2 . TYR C 2 473 ? 228.702 195.083 158.193 1.00 60.71  ? 473  TYR A CD2 1 
ATOM   8329 C CE1 . TYR C 2 473 ? 227.212 193.823 160.141 1.00 60.71  ? 473  TYR A CE1 1 
ATOM   8330 C CE2 . TYR C 2 473 ? 227.338 194.937 158.029 1.00 60.71  ? 473  TYR A CE2 1 
ATOM   8331 C CZ  . TYR C 2 473 ? 226.598 194.307 159.006 1.00 60.71  ? 473  TYR A CZ  1 
ATOM   8332 O OH  . TYR C 2 473 ? 225.240 194.158 158.847 1.00 60.71  ? 473  TYR A OH  1 
ATOM   8333 N N   . GLN C 2 474 ? 230.980 191.785 157.619 1.00 63.46  ? 474  GLN A N   1 
ATOM   8334 C CA  . GLN C 2 474 ? 230.689 191.207 156.309 1.00 63.46  ? 474  GLN A CA  1 
ATOM   8335 C C   . GLN C 2 474 ? 229.254 191.565 155.942 1.00 63.46  ? 474  GLN A C   1 
ATOM   8336 O O   . GLN C 2 474 ? 228.303 190.940 156.418 1.00 63.46  ? 474  GLN A O   1 
ATOM   8337 C CB  . GLN C 2 474 ? 230.907 189.698 156.326 1.00 63.46  ? 474  GLN A CB  1 
ATOM   8338 C CG  . GLN C 2 474 ? 230.659 189.017 154.993 1.00 63.46  ? 474  GLN A CG  1 
ATOM   8339 C CD  . GLN C 2 474 ? 230.934 187.528 155.040 1.00 63.46  ? 474  GLN A CD  1 
ATOM   8340 O OE1 . GLN C 2 474 ? 231.451 187.012 156.031 1.00 63.46  ? 474  GLN A OE1 1 
ATOM   8341 N NE2 . GLN C 2 474 ? 230.588 186.827 153.967 1.00 63.46  ? 474  GLN A NE2 1 
ATOM   8342 N N   . ALA C 2 475 ? 229.097 192.577 155.091 1.00 60.79  ? 475  ALA A N   1 
ATOM   8343 C CA  . ALA C 2 475 ? 227.781 193.055 154.693 1.00 60.79  ? 475  ALA A CA  1 
ATOM   8344 C C   . ALA C 2 475 ? 227.202 192.301 153.503 1.00 60.79  ? 475  ALA A C   1 
ATOM   8345 O O   . ALA C 2 475 ? 226.021 192.485 153.191 1.00 60.79  ? 475  ALA A O   1 
ATOM   8346 C CB  . ALA C 2 475 ? 227.838 194.551 154.366 1.00 60.79  ? 475  ALA A CB  1 
ATOM   8347 N N   . GLY C 2 476 ? 227.993 191.465 152.837 1.00 62.39  ? 476  GLY A N   1 
ATOM   8348 C CA  . GLY C 2 476 ? 227.508 190.730 151.686 1.00 62.39  ? 476  GLY A CA  1 
ATOM   8349 C C   . GLY C 2 476 ? 227.813 189.248 151.748 1.00 62.39  ? 476  GLY A C   1 
ATOM   8350 O O   . GLY C 2 476 ? 228.268 188.742 152.777 1.00 62.39  ? 476  GLY A O   1 
ATOM   8351 N N   . SER C 2 477 ? 227.563 188.539 150.646 1.00 66.27  ? 477  SER A N   1 
ATOM   8352 C CA  . SER C 2 477 ? 227.823 187.107 150.596 1.00 66.27  ? 477  SER A CA  1 
ATOM   8353 C C   . SER C 2 477 ? 229.298 186.781 150.411 1.00 66.27  ? 477  SER A C   1 
ATOM   8354 O O   . SER C 2 477 ? 229.715 185.661 150.726 1.00 66.27  ? 477  SER A O   1 
ATOM   8355 C CB  . SER C 2 477 ? 227.011 186.463 149.470 1.00 66.27  ? 477  SER A CB  1 
ATOM   8356 O OG  . SER C 2 477 ? 227.357 187.017 148.212 1.00 66.27  ? 477  SER A OG  1 
ATOM   8357 N N   . THR C 2 478 ? 230.090 187.721 149.913 1.00 66.53  ? 478  THR A N   1 
ATOM   8358 C CA  . THR C 2 478 ? 231.508 187.464 149.700 1.00 66.53  ? 478  THR A CA  1 
ATOM   8359 C C   . THR C 2 478 ? 232.235 187.428 151.040 1.00 66.53  ? 478  THR A C   1 
ATOM   8360 O O   . THR C 2 478 ? 232.114 188.371 151.831 1.00 66.53  ? 478  THR A O   1 
ATOM   8361 C CB  . THR C 2 478 ? 232.119 188.534 148.798 1.00 66.53  ? 478  THR A CB  1 
ATOM   8362 O OG1 . THR C 2 478 ? 231.446 188.535 147.532 1.00 66.53  ? 478  THR A OG1 1 
ATOM   8363 C CG2 . THR C 2 478 ? 233.600 188.264 148.578 1.00 66.53  ? 478  THR A CG2 1 
ATOM   8364 N N   . PRO C 2 479 ? 232.986 186.366 151.336 1.00 66.71  ? 479  PRO A N   1 
ATOM   8365 C CA  . PRO C 2 479 ? 233.703 186.302 152.617 1.00 66.71  ? 479  PRO A CA  1 
ATOM   8366 C C   . PRO C 2 479 ? 234.812 187.342 152.677 1.00 66.71  ? 479  PRO A C   1 
ATOM   8367 O O   . PRO C 2 479 ? 235.645 187.437 151.773 1.00 66.71  ? 479  PRO A O   1 
ATOM   8368 C CB  . PRO C 2 479 ? 234.266 184.875 152.641 1.00 66.71  ? 479  PRO A CB  1 
ATOM   8369 C CG  . PRO C 2 479 ? 233.461 184.119 151.626 1.00 66.71  ? 479  PRO A CG  1 
ATOM   8370 C CD  . PRO C 2 479 ? 233.114 185.117 150.568 1.00 66.71  ? 479  PRO A CD  1 
ATOM   8371 N N   . CYS C 2 480 ? 234.818 188.121 153.755 1.00 71.18  ? 480  CYS A N   1 
ATOM   8372 C CA  . CYS C 2 480 ? 235.852 189.125 153.970 1.00 71.18  ? 480  CYS A CA  1 
ATOM   8373 C C   . CYS C 2 480 ? 237.065 188.465 154.614 1.00 71.18  ? 480  CYS A C   1 
ATOM   8374 O O   . CYS C 2 480 ? 236.966 187.913 155.715 1.00 71.18  ? 480  CYS A O   1 
ATOM   8375 C CB  . CYS C 2 480 ? 235.323 190.259 154.846 1.00 71.18  ? 480  CYS A CB  1 
ATOM   8376 S SG  . CYS C 2 480 ? 233.832 191.065 154.214 1.00 71.18  ? 480  CYS A SG  1 
ATOM   8377 N N   . ASN C 2 481 ? 238.207 188.521 153.931 1.00 73.95  ? 481  ASN A N   1 
ATOM   8378 C CA  . ASN C 2 481 ? 239.419 187.884 154.429 1.00 73.95  ? 481  ASN A CA  1 
ATOM   8379 C C   . ASN C 2 481 ? 240.140 188.788 155.423 1.00 73.95  ? 481  ASN A C   1 
ATOM   8380 O O   . ASN C 2 481 ? 241.332 189.070 155.265 1.00 73.95  ? 481  ASN A O   1 
ATOM   8381 C CB  . ASN C 2 481 ? 240.344 187.518 153.265 1.00 73.95  ? 481  ASN A CB  1 
ATOM   8382 C CG  . ASN C 2 481 ? 241.413 186.516 153.660 1.00 73.95  ? 481  ASN A CG  1 
ATOM   8383 O OD1 . ASN C 2 481 ? 242.547 186.886 153.964 1.00 73.95  ? 481  ASN A OD1 1 
ATOM   8384 N ND2 . ASN C 2 481 ? 241.053 185.237 153.657 1.00 73.95  ? 481  ASN A ND2 1 
ATOM   8385 N N   . GLY C 2 482 ? 239.422 189.250 156.445 1.00 68.95  ? 482  GLY A N   1 
ATOM   8386 C CA  . GLY C 2 482 ? 240.011 190.074 157.483 1.00 68.95  ? 482  GLY A CA  1 
ATOM   8387 C C   . GLY C 2 482 ? 240.513 191.422 157.007 1.00 68.95  ? 482  GLY A C   1 
ATOM   8388 O O   . GLY C 2 482 ? 241.251 192.102 157.726 1.00 68.95  ? 482  GLY A O   1 
ATOM   8389 N N   . VAL C 2 483 ? 240.123 191.822 155.799 1.00 66.51  ? 483  VAL A N   1 
ATOM   8390 C CA  . VAL C 2 483 ? 240.552 193.086 155.216 1.00 66.51  ? 483  VAL A CA  1 
ATOM   8391 C C   . VAL C 2 483 ? 239.328 193.855 154.743 1.00 66.51  ? 483  VAL A C   1 
ATOM   8392 O O   . VAL C 2 483 ? 238.289 193.272 154.417 1.00 66.51  ? 483  VAL A O   1 
ATOM   8393 C CB  . VAL C 2 483 ? 241.546 192.879 154.051 1.00 66.51  ? 483  VAL A CB  1 
ATOM   8394 C CG1 . VAL C 2 483 ? 242.841 192.265 154.559 1.00 66.51  ? 483  VAL A CG1 1 
ATOM   8395 C CG2 . VAL C 2 483 ? 240.925 192.007 152.971 1.00 66.51  ? 483  VAL A CG2 1 
ATOM   8396 N N   . GLU C 2 484 ? 239.456 195.178 154.712 1.00 69.64  ? 484  GLU A N   1 
ATOM   8397 C CA  . GLU C 2 484 ? 238.367 196.035 154.275 1.00 69.64  ? 484  GLU A CA  1 
ATOM   8398 C C   . GLU C 2 484 ? 238.255 196.028 152.753 1.00 69.64  ? 484  GLU A C   1 
ATOM   8399 O O   . GLU C 2 484 ? 239.194 195.676 152.034 1.00 69.64  ? 484  GLU A O   1 
ATOM   8400 C CB  . GLU C 2 484 ? 238.572 197.463 154.780 1.00 69.64  ? 484  GLU A CB  1 
ATOM   8401 C CG  . GLU C 2 484 ? 238.690 197.576 156.290 1.00 69.64  ? 484  GLU A CG  1 
ATOM   8402 C CD  . GLU C 2 484 ? 238.919 199.002 156.751 1.00 69.64  ? 484  GLU A CD  1 
ATOM   8403 O OE1 . GLU C 2 484 ? 238.926 199.911 155.894 1.00 69.64  ? 484  GLU A OE1 1 
ATOM   8404 O OE2 . GLU C 2 484 ? 239.091 199.214 157.969 1.00 69.64  ? 484  GLU A OE2 1 
ATOM   8405 N N   . GLY C 2 485 ? 237.088 196.424 152.269 1.00 65.20  ? 485  GLY A N   1 
ATOM   8406 C CA  . GLY C 2 485 ? 236.843 196.462 150.836 1.00 65.20  ? 485  GLY A CA  1 
ATOM   8407 C C   . GLY C 2 485 ? 235.351 196.518 150.549 1.00 65.20  ? 485  GLY A C   1 
ATOM   8408 O O   . GLY C 2 485 ? 234.574 197.050 151.343 1.00 65.20  ? 485  GLY A O   1 
ATOM   8409 N N   . PHE C 2 486 ? 234.981 195.960 149.400 1.00 63.22  ? 486  PHE A N   1 
ATOM   8410 C CA  . PHE C 2 486 ? 233.583 195.929 148.988 1.00 63.22  ? 486  PHE A CA  1 
ATOM   8411 C C   . PHE C 2 486 ? 232.792 195.011 149.913 1.00 63.22  ? 486  PHE A C   1 
ATOM   8412 O O   . PHE C 2 486 ? 233.142 193.838 150.081 1.00 63.22  ? 486  PHE A O   1 
ATOM   8413 C CB  . PHE C 2 486 ? 233.473 195.466 147.538 1.00 63.22  ? 486  PHE A CB  1 
ATOM   8414 C CG  . PHE C 2 486 ? 232.070 195.464 147.005 1.00 63.22  ? 486  PHE A CG  1 
ATOM   8415 C CD1 . PHE C 2 486 ? 231.373 196.650 146.850 1.00 63.22  ? 486  PHE A CD1 1 
ATOM   8416 C CD2 . PHE C 2 486 ? 231.453 194.278 146.646 1.00 63.22  ? 486  PHE A CD2 1 
ATOM   8417 C CE1 . PHE C 2 486 ? 230.083 196.652 146.356 1.00 63.22  ? 486  PHE A CE1 1 
ATOM   8418 C CE2 . PHE C 2 486 ? 230.163 194.274 146.151 1.00 63.22  ? 486  PHE A CE2 1 
ATOM   8419 C CZ  . PHE C 2 486 ? 229.478 195.463 146.006 1.00 63.22  ? 486  PHE A CZ  1 
ATOM   8420 N N   . ASN C 2 487 ? 231.731 195.552 150.517 1.00 61.62  ? 487  ASN A N   1 
ATOM   8421 C CA  . ASN C 2 487 ? 230.899 194.830 151.483 1.00 61.62  ? 487  ASN A CA  1 
ATOM   8422 C C   . ASN C 2 487 ? 231.712 194.338 152.678 1.00 61.62  ? 487  ASN A C   1 
ATOM   8423 O O   . ASN C 2 487 ? 231.339 193.365 153.338 1.00 61.62  ? 487  ASN A O   1 
ATOM   8424 C CB  . ASN C 2 487 ? 230.156 193.663 150.825 1.00 61.62  ? 487  ASN A CB  1 
ATOM   8425 C CG  . ASN C 2 487 ? 229.112 194.124 149.829 1.00 61.62  ? 487  ASN A CG  1 
ATOM   8426 O OD1 . ASN C 2 487 ? 228.623 195.251 149.902 1.00 61.62  ? 487  ASN A OD1 1 
ATOM   8427 N ND2 . ASN C 2 487 ? 228.761 193.250 148.893 1.00 61.62  ? 487  ASN A ND2 1 
ATOM   8428 N N   . CYS C 2 488 ? 232.828 195.006 152.966 1.00 63.65  ? 488  CYS A N   1 
ATOM   8429 C CA  . CYS C 2 488 ? 233.683 194.664 154.104 1.00 63.65  ? 488  CYS A CA  1 
ATOM   8430 C C   . CYS C 2 488 ? 234.092 195.974 154.769 1.00 63.65  ? 488  CYS A C   1 
ATOM   8431 O O   . CYS C 2 488 ? 235.028 196.640 154.316 1.00 63.65  ? 488  CYS A O   1 
ATOM   8432 C CB  . CYS C 2 488 ? 234.898 193.856 153.666 1.00 63.65  ? 488  CYS A CB  1 
ATOM   8433 S SG  . CYS C 2 488 ? 234.508 192.329 152.776 1.00 63.65  ? 488  CYS A SG  1 
ATOM   8434 N N   . TYR C 2 489 ? 233.392 196.339 155.839 1.00 57.62  ? 489  TYR A N   1 
ATOM   8435 C CA  . TYR C 2 489 ? 233.604 197.606 156.522 1.00 57.62  ? 489  TYR A CA  1 
ATOM   8436 C C   . TYR C 2 489 ? 234.072 197.364 157.950 1.00 57.62  ? 489  TYR A C   1 
ATOM   8437 O O   . TYR C 2 489 ? 233.726 196.355 158.573 1.00 57.62  ? 489  TYR A O   1 
ATOM   8438 C CB  . TYR C 2 489 ? 232.324 198.451 156.535 1.00 57.62  ? 489  TYR A CB  1 
ATOM   8439 C CG  . TYR C 2 489 ? 231.662 198.585 155.183 1.00 57.62  ? 489  TYR A CG  1 
ATOM   8440 C CD1 . TYR C 2 489 ? 232.073 199.556 154.280 1.00 57.62  ? 489  TYR A CD1 1 
ATOM   8441 C CD2 . TYR C 2 489 ? 230.623 197.743 154.810 1.00 57.62  ? 489  TYR A CD2 1 
ATOM   8442 C CE1 . TYR C 2 489 ? 231.470 199.682 153.043 1.00 57.62  ? 489  TYR A CE1 1 
ATOM   8443 C CE2 . TYR C 2 489 ? 230.014 197.862 153.576 1.00 57.62  ? 489  TYR A CE2 1 
ATOM   8444 C CZ  . TYR C 2 489 ? 230.442 198.832 152.697 1.00 57.62  ? 489  TYR A CZ  1 
ATOM   8445 O OH  . TYR C 2 489 ? 229.838 198.954 151.467 1.00 57.62  ? 489  TYR A OH  1 
ATOM   8446 N N   . PHE C 2 490 ? 234.867 198.302 158.462 1.00 58.55  ? 490  PHE A N   1 
ATOM   8447 C CA  . PHE C 2 490 ? 235.315 198.229 159.845 1.00 58.55  ? 490  PHE A CA  1 
ATOM   8448 C C   . PHE C 2 490 ? 234.173 198.626 160.780 1.00 58.55  ? 490  PHE A C   1 
ATOM   8449 O O   . PHE C 2 490 ? 233.468 199.604 160.518 1.00 58.55  ? 490  PHE A O   1 
ATOM   8450 C CB  . PHE C 2 490 ? 236.518 199.143 160.067 1.00 58.55  ? 490  PHE A CB  1 
ATOM   8451 C CG  . PHE C 2 490 ? 237.318 198.808 161.294 1.00 58.55  ? 490  PHE A CG  1 
ATOM   8452 C CD1 . PHE C 2 490 ? 238.291 197.825 161.254 1.00 58.55  ? 490  PHE A CD1 1 
ATOM   8453 C CD2 . PHE C 2 490 ? 237.101 199.481 162.485 1.00 58.55  ? 490  PHE A CD2 1 
ATOM   8454 C CE1 . PHE C 2 490 ? 239.031 197.515 162.379 1.00 58.55  ? 490  PHE A CE1 1 
ATOM   8455 C CE2 . PHE C 2 490 ? 237.838 199.175 163.613 1.00 58.55  ? 490  PHE A CE2 1 
ATOM   8456 C CZ  . PHE C 2 490 ? 238.804 198.192 163.560 1.00 58.55  ? 490  PHE A CZ  1 
ATOM   8457 N N   . PRO C 2 491 ? 233.969 197.889 161.875 1.00 57.32  ? 491  PRO A N   1 
ATOM   8458 C CA  . PRO C 2 491 ? 232.794 198.157 162.717 1.00 57.32  ? 491  PRO A CA  1 
ATOM   8459 C C   . PRO C 2 491 ? 232.917 199.417 163.556 1.00 57.32  ? 491  PRO A C   1 
ATOM   8460 O O   . PRO C 2 491 ? 231.895 200.050 163.848 1.00 57.32  ? 491  PRO A O   1 
ATOM   8461 C CB  . PRO C 2 491 ? 232.704 196.902 163.595 1.00 57.32  ? 491  PRO A CB  1 
ATOM   8462 C CG  . PRO C 2 491 ? 234.114 196.429 163.694 1.00 57.32  ? 491  PRO A CG  1 
ATOM   8463 C CD  . PRO C 2 491 ? 234.753 196.742 162.365 1.00 57.32  ? 491  PRO A CD  1 
ATOM   8464 N N   . LEU C 2 492 ? 234.125 199.803 163.952 1.00 55.64  ? 492  LEU A N   1 
ATOM   8465 C CA  . LEU C 2 492 ? 234.332 200.953 164.823 1.00 55.64  ? 492  LEU A CA  1 
ATOM   8466 C C   . LEU C 2 492 ? 234.661 202.184 163.989 1.00 55.64  ? 492  LEU A C   1 
ATOM   8467 O O   . LEU C 2 492 ? 235.556 202.145 163.138 1.00 55.64  ? 492  LEU A O   1 
ATOM   8468 C CB  . LEU C 2 492 ? 235.453 200.680 165.827 1.00 55.64  ? 492  LEU A CB  1 
ATOM   8469 C CG  . LEU C 2 492 ? 235.227 199.514 166.792 1.00 55.64  ? 492  LEU A CG  1 
ATOM   8470 C CD1 . LEU C 2 492 ? 236.407 199.366 167.740 1.00 55.64  ? 492  LEU A CD1 1 
ATOM   8471 C CD2 . LEU C 2 492 ? 233.933 199.701 167.567 1.00 55.64  ? 492  LEU A CD2 1 
ATOM   8472 N N   . GLN C 2 493 ? 233.936 203.272 164.239 1.00 56.08  ? 493  GLN A N   1 
ATOM   8473 C CA  . GLN C 2 493 ? 234.155 204.541 163.562 1.00 56.08  ? 493  GLN A CA  1 
ATOM   8474 C C   . GLN C 2 493 ? 234.369 205.631 164.602 1.00 56.08  ? 493  GLN A C   1 
ATOM   8475 O O   . GLN C 2 493 ? 233.734 205.623 165.660 1.00 56.08  ? 493  GLN A O   1 
ATOM   8476 C CB  . GLN C 2 493 ? 232.975 204.899 162.651 1.00 56.08  ? 493  GLN A CB  1 
ATOM   8477 C CG  . GLN C 2 493 ? 232.732 203.899 161.531 1.00 56.08  ? 493  GLN A CG  1 
ATOM   8478 C CD  . GLN C 2 493 ? 233.889 203.820 160.553 1.00 56.08  ? 493  GLN A CD  1 
ATOM   8479 O OE1 . GLN C 2 493 ? 234.185 202.756 160.010 1.00 56.08  ? 493  GLN A OE1 1 
ATOM   8480 N NE2 . GLN C 2 493 ? 234.545 204.950 160.317 1.00 56.08  ? 493  GLN A NE2 1 
ATOM   8481 N N   . SER C 2 494 ? 235.261 206.568 164.294 1.00 54.84  ? 494  SER A N   1 
ATOM   8482 C CA  . SER C 2 494 ? 235.675 207.584 165.251 1.00 54.84  ? 494  SER A CA  1 
ATOM   8483 C C   . SER C 2 494 ? 234.831 208.845 165.114 1.00 54.84  ? 494  SER A C   1 
ATOM   8484 O O   . SER C 2 494 ? 234.446 209.235 164.008 1.00 54.84  ? 494  SER A O   1 
ATOM   8485 C CB  . SER C 2 494 ? 237.153 207.926 165.060 1.00 54.84  ? 494  SER A CB  1 
ATOM   8486 O OG  . SER C 2 494 ? 237.578 208.893 166.004 1.00 54.84  ? 494  SER A OG  1 
ATOM   8487 N N   . TYR C 2 495 ? 234.550 209.480 166.249 1.00 55.54  ? 495  TYR A N   1 
ATOM   8488 C CA  . TYR C 2 495 ? 233.816 210.736 166.261 1.00 55.54  ? 495  TYR A CA  1 
ATOM   8489 C C   . TYR C 2 495 ? 234.722 211.897 165.869 1.00 55.54  ? 495  TYR A C   1 
ATOM   8490 O O   . TYR C 2 495 ? 235.919 211.911 166.168 1.00 55.54  ? 495  TYR A O   1 
ATOM   8491 C CB  . TYR C 2 495 ? 233.224 211.008 167.645 1.00 55.54  ? 495  TYR A CB  1 
ATOM   8492 C CG  . TYR C 2 495 ? 231.949 210.258 167.951 1.00 55.54  ? 495  TYR A CG  1 
ATOM   8493 C CD1 . TYR C 2 495 ? 230.758 210.586 167.318 1.00 55.54  ? 495  TYR A CD1 1 
ATOM   8494 C CD2 . TYR C 2 495 ? 231.930 209.239 168.894 1.00 55.54  ? 495  TYR A CD2 1 
ATOM   8495 C CE1 . TYR C 2 495 ? 229.587 209.909 167.601 1.00 55.54  ? 495  TYR A CE1 1 
ATOM   8496 C CE2 . TYR C 2 495 ? 230.764 208.558 169.185 1.00 55.54  ? 495  TYR A CE2 1 
ATOM   8497 C CZ  . TYR C 2 495 ? 229.596 208.897 168.536 1.00 55.54  ? 495  TYR A CZ  1 
ATOM   8498 O OH  . TYR C 2 495 ? 228.433 208.220 168.822 1.00 55.54  ? 495  TYR A OH  1 
ATOM   8499 N N   . GLY C 2 496 ? 234.133 212.879 165.192 1.00 56.25  ? 496  GLY A N   1 
ATOM   8500 C CA  . GLY C 2 496 ? 234.830 214.113 164.893 1.00 56.25  ? 496  GLY A CA  1 
ATOM   8501 C C   . GLY C 2 496 ? 234.387 215.238 165.805 1.00 56.25  ? 496  GLY A C   1 
ATOM   8502 O O   . GLY C 2 496 ? 233.307 215.806 165.617 1.00 56.25  ? 496  GLY A O   1 
ATOM   8503 N N   . PHE C 2 497 ? 235.209 215.570 166.796 1.00 55.59  ? 497  PHE A N   1 
ATOM   8504 C CA  . PHE C 2 497 ? 234.864 216.559 167.815 1.00 55.59  ? 497  PHE A CA  1 
ATOM   8505 C C   . PHE C 2 497 ? 235.730 217.799 167.618 1.00 55.59  ? 497  PHE A C   1 
ATOM   8506 O O   . PHE C 2 497 ? 236.862 217.862 168.104 1.00 55.59  ? 497  PHE A O   1 
ATOM   8507 C CB  . PHE C 2 497 ? 235.039 215.977 169.214 1.00 55.59  ? 497  PHE A CB  1 
ATOM   8508 C CG  . PHE C 2 497 ? 233.983 214.978 169.591 1.00 55.59  ? 497  PHE A CG  1 
ATOM   8509 C CD1 . PHE C 2 497 ? 232.707 215.066 169.061 1.00 55.59  ? 497  PHE A CD1 1 
ATOM   8510 C CD2 . PHE C 2 497 ? 234.266 213.950 170.475 1.00 55.59  ? 497  PHE A CD2 1 
ATOM   8511 C CE1 . PHE C 2 497 ? 231.733 214.149 169.406 1.00 55.59  ? 497  PHE A CE1 1 
ATOM   8512 C CE2 . PHE C 2 497 ? 233.297 213.030 170.823 1.00 55.59  ? 497  PHE A CE2 1 
ATOM   8513 C CZ  . PHE C 2 497 ? 232.028 213.130 170.288 1.00 55.59  ? 497  PHE A CZ  1 
ATOM   8514 N N   . GLN C 2 498 ? 235.190 218.785 166.902 1.00 54.71  ? 498  GLN A N   1 
ATOM   8515 C CA  . GLN C 2 498 ? 235.818 220.084 166.740 1.00 54.71  ? 498  GLN A CA  1 
ATOM   8516 C C   . GLN C 2 498 ? 235.162 221.105 167.662 1.00 54.71  ? 498  GLN A C   1 
ATOM   8517 O O   . GLN C 2 498 ? 233.970 220.999 167.967 1.00 54.71  ? 498  GLN A O   1 
ATOM   8518 C CB  . GLN C 2 498 ? 235.716 220.567 165.289 1.00 54.71  ? 498  GLN A CB  1 
ATOM   8519 C CG  . GLN C 2 498 ? 236.542 219.767 164.291 1.00 54.71  ? 498  GLN A CG  1 
ATOM   8520 C CD  . GLN C 2 498 ? 235.879 218.467 163.881 1.00 54.71  ? 498  GLN A CD  1 
ATOM   8521 O OE1 . GLN C 2 498 ? 234.780 218.147 164.333 1.00 54.71  ? 498  GLN A OE1 1 
ATOM   8522 N NE2 . GLN C 2 498 ? 236.545 217.712 163.015 1.00 54.71  ? 498  GLN A NE2 1 
ATOM   8523 N N   . PRO C 2 499 ? 235.910 222.109 168.131 1.00 54.33  ? 499  PRO A N   1 
ATOM   8524 C CA  . PRO C 2 499 ? 235.320 223.098 169.048 1.00 54.33  ? 499  PRO A CA  1 
ATOM   8525 C C   . PRO C 2 499 ? 234.310 224.023 168.390 1.00 54.33  ? 499  PRO A C   1 
ATOM   8526 O O   . PRO C 2 499 ? 233.581 224.719 169.109 1.00 54.33  ? 499  PRO A O   1 
ATOM   8527 C CB  . PRO C 2 499 ? 236.540 223.879 169.550 1.00 54.33  ? 499  PRO A CB  1 
ATOM   8528 C CG  . PRO C 2 499 ? 237.538 223.748 168.452 1.00 54.33  ? 499  PRO A CG  1 
ATOM   8529 C CD  . PRO C 2 499 ? 237.337 222.374 167.876 1.00 54.33  ? 499  PRO A CD  1 
ATOM   8530 N N   . THR C 2 500 ? 234.238 224.055 167.062 1.00 54.66  ? 500  THR A N   1 
ATOM   8531 C CA  . THR C 2 500 ? 233.297 224.911 166.354 1.00 54.66  ? 500  THR A CA  1 
ATOM   8532 C C   . THR C 2 500 ? 231.998 224.199 165.998 1.00 54.66  ? 500  THR A C   1 
ATOM   8533 O O   . THR C 2 500 ? 231.140 224.800 165.344 1.00 54.66  ? 500  THR A O   1 
ATOM   8534 C CB  . THR C 2 500 ? 233.941 225.466 165.080 1.00 54.66  ? 500  THR A CB  1 
ATOM   8535 O OG1 . THR C 2 500 ? 234.347 224.382 164.235 1.00 54.66  ? 500  THR A OG1 1 
ATOM   8536 C CG2 . THR C 2 500 ? 235.155 226.315 165.424 1.00 54.66  ? 500  THR A CG2 1 
ATOM   8537 N N   . ASN C 2 501 ? 231.835 222.944 166.407 1.00 55.14  ? 501  ASN A N   1 
ATOM   8538 C CA  . ASN C 2 501 ? 230.608 222.216 166.119 1.00 55.14  ? 501  ASN A CA  1 
ATOM   8539 C C   . ASN C 2 501 ? 229.446 222.787 166.922 1.00 55.14  ? 501  ASN A C   1 
ATOM   8540 O O   . ASN C 2 501 ? 229.606 223.191 168.077 1.00 55.14  ? 501  ASN A O   1 
ATOM   8541 C CB  . ASN C 2 501 ? 230.784 220.732 166.438 1.00 55.14  ? 501  ASN A CB  1 
ATOM   8542 C CG  . ASN C 2 501 ? 231.832 220.070 165.569 1.00 55.14  ? 501  ASN A CG  1 
ATOM   8543 O OD1 . ASN C 2 501 ? 232.538 220.736 164.814 1.00 55.14  ? 501  ASN A OD1 1 
ATOM   8544 N ND2 . ASN C 2 501 ? 231.942 218.752 165.676 1.00 55.14  ? 501  ASN A ND2 1 
ATOM   8545 N N   . GLY C 2 502 ? 228.270 222.820 166.300 1.00 54.42  ? 502  GLY A N   1 
ATOM   8546 C CA  . GLY C 2 502 ? 227.076 223.290 166.965 1.00 54.42  ? 502  GLY A CA  1 
ATOM   8547 C C   . GLY C 2 502 ? 226.526 222.272 167.945 1.00 54.42  ? 502  GLY A C   1 
ATOM   8548 O O   . GLY C 2 502 ? 227.032 221.160 168.094 1.00 54.42  ? 502  GLY A O   1 
ATOM   8549 N N   . VAL C 2 503 ? 225.457 222.677 168.631 1.00 56.63  ? 503  VAL A N   1 
ATOM   8550 C CA  . VAL C 2 503 ? 224.805 221.793 169.589 1.00 56.63  ? 503  VAL A CA  1 
ATOM   8551 C C   . VAL C 2 503 ? 224.205 220.605 168.850 1.00 56.63  ? 503  VAL A C   1 
ATOM   8552 O O   . VAL C 2 503 ? 223.507 220.765 167.840 1.00 56.63  ? 503  VAL A O   1 
ATOM   8553 C CB  . VAL C 2 503 ? 223.743 222.560 170.393 1.00 56.63  ? 503  VAL A CB  1 
ATOM   8554 C CG1 . VAL C 2 503 ? 222.842 223.366 169.467 1.00 56.63  ? 503  VAL A CG1 1 
ATOM   8555 C CG2 . VAL C 2 503 ? 222.924 221.602 171.246 1.00 56.63  ? 503  VAL A CG2 1 
ATOM   8556 N N   . GLY C 2 504 ? 224.488 219.403 169.343 1.00 54.13  ? 504  GLY A N   1 
ATOM   8557 C CA  . GLY C 2 504 ? 224.049 218.193 168.679 1.00 54.13  ? 504  GLY A CA  1 
ATOM   8558 C C   . GLY C 2 504 ? 225.213 217.342 168.216 1.00 54.13  ? 504  GLY A C   1 
ATOM   8559 O O   . GLY C 2 504 ? 225.163 216.111 168.292 1.00 54.13  ? 504  GLY A O   1 
ATOM   8560 N N   . TYR C 2 505 ? 226.268 217.992 167.730 1.00 53.54  ? 505  TYR A N   1 
ATOM   8561 C CA  . TYR C 2 505 ? 227.488 217.312 167.321 1.00 53.54  ? 505  TYR A CA  1 
ATOM   8562 C C   . TYR C 2 505 ? 228.610 217.451 168.340 1.00 53.54  ? 505  TYR A C   1 
ATOM   8563 O O   . TYR C 2 505 ? 229.689 216.887 168.135 1.00 53.54  ? 505  TYR A O   1 
ATOM   8564 C CB  . TYR C 2 505 ? 227.958 217.839 165.961 1.00 53.54  ? 505  TYR A CB  1 
ATOM   8565 C CG  . TYR C 2 505 ? 227.098 217.395 164.800 1.00 53.54  ? 505  TYR A CG  1 
ATOM   8566 C CD1 . TYR C 2 505 ? 225.978 218.122 164.421 1.00 53.54  ? 505  TYR A CD1 1 
ATOM   8567 C CD2 . TYR C 2 505 ? 227.408 216.248 164.082 1.00 53.54  ? 505  TYR A CD2 1 
ATOM   8568 C CE1 . TYR C 2 505 ? 225.191 217.719 163.359 1.00 53.54  ? 505  TYR A CE1 1 
ATOM   8569 C CE2 . TYR C 2 505 ? 226.627 215.837 163.019 1.00 53.54  ? 505  TYR A CE2 1 
ATOM   8570 C CZ  . TYR C 2 505 ? 225.520 216.576 162.663 1.00 53.54  ? 505  TYR A CZ  1 
ATOM   8571 O OH  . TYR C 2 505 ? 224.739 216.170 161.605 1.00 53.54  ? 505  TYR A OH  1 
ATOM   8572 N N   . GLN C 2 506 ? 228.385 218.185 169.427 1.00 54.45  ? 506  GLN A N   1 
ATOM   8573 C CA  . GLN C 2 506 ? 229.403 218.365 170.448 1.00 54.45  ? 506  GLN A CA  1 
ATOM   8574 C C   . GLN C 2 506 ? 229.456 217.151 171.374 1.00 54.45  ? 506  GLN A C   1 
ATOM   8575 O O   . GLN C 2 506 ? 228.449 216.467 171.572 1.00 54.45  ? 506  GLN A O   1 
ATOM   8576 C CB  . GLN C 2 506 ? 229.123 219.624 171.262 1.00 54.45  ? 506  GLN A CB  1 
ATOM   8577 C CG  . GLN C 2 506 ? 229.255 220.914 170.469 1.00 54.45  ? 506  GLN A CG  1 
ATOM   8578 C CD  . GLN C 2 506 ? 228.983 222.145 171.309 1.00 54.45  ? 506  GLN A CD  1 
ATOM   8579 O OE1 . GLN C 2 506 ? 228.633 222.044 172.484 1.00 54.45  ? 506  GLN A OE1 1 
ATOM   8580 N NE2 . GLN C 2 506 ? 229.146 223.318 170.708 1.00 54.45  ? 506  GLN A NE2 1 
ATOM   8581 N N   . PRO C 2 507 ? 230.625 216.858 171.946 1.00 55.11  ? 507  PRO A N   1 
ATOM   8582 C CA  . PRO C 2 507 ? 230.734 215.703 172.848 1.00 55.11  ? 507  PRO A CA  1 
ATOM   8583 C C   . PRO C 2 507 ? 229.979 215.942 174.147 1.00 55.11  ? 507  PRO A C   1 
ATOM   8584 O O   . PRO C 2 507 ? 230.103 216.998 174.771 1.00 55.11  ? 507  PRO A O   1 
ATOM   8585 C CB  . PRO C 2 507 ? 232.244 215.580 173.086 1.00 55.11  ? 507  PRO A CB  1 
ATOM   8586 C CG  . PRO C 2 507 ? 232.772 216.953 172.839 1.00 55.11  ? 507  PRO A CG  1 
ATOM   8587 C CD  . PRO C 2 507 ? 231.922 217.524 171.743 1.00 55.11  ? 507  PRO A CD  1 
ATOM   8588 N N   . TYR C 2 508 ? 229.192 214.947 174.550 1.00 54.86  ? 508  TYR A N   1 
ATOM   8589 C CA  . TYR C 2 508 ? 228.408 214.991 175.780 1.00 54.86  ? 508  TYR A CA  1 
ATOM   8590 C C   . TYR C 2 508 ? 228.792 213.797 176.642 1.00 54.86  ? 508  TYR A C   1 
ATOM   8591 O O   . TYR C 2 508 ? 228.501 212.650 176.286 1.00 54.86  ? 508  TYR A O   1 
ATOM   8592 C CB  . TYR C 2 508 ? 226.910 214.984 175.477 1.00 54.86  ? 508  TYR A CB  1 
ATOM   8593 C CG  . TYR C 2 508 ? 226.316 216.353 175.235 1.00 54.86  ? 508  TYR A CG  1 
ATOM   8594 C CD1 . TYR C 2 508 ? 226.575 217.046 174.061 1.00 54.86  ? 508  TYR A CD1 1 
ATOM   8595 C CD2 . TYR C 2 508 ? 225.486 216.946 176.176 1.00 54.86  ? 508  TYR A CD2 1 
ATOM   8596 C CE1 . TYR C 2 508 ? 226.031 218.296 173.835 1.00 54.86  ? 508  TYR A CE1 1 
ATOM   8597 C CE2 . TYR C 2 508 ? 224.936 218.194 175.959 1.00 54.86  ? 508  TYR A CE2 1 
ATOM   8598 C CZ  . TYR C 2 508 ? 225.212 218.864 174.787 1.00 54.86  ? 508  TYR A CZ  1 
ATOM   8599 O OH  . TYR C 2 508 ? 224.667 220.108 174.566 1.00 54.86  ? 508  TYR A OH  1 
ATOM   8600 N N   . ARG C 2 509 ? 229.447 214.063 177.769 1.00 56.49  ? 509  ARG A N   1 
ATOM   8601 C CA  . ARG C 2 509 ? 229.775 213.004 178.714 1.00 56.49  ? 509  ARG A CA  1 
ATOM   8602 C C   . ARG C 2 509 ? 228.519 212.592 179.472 1.00 56.49  ? 509  ARG A C   1 
ATOM   8603 O O   . ARG C 2 509 ? 227.908 213.410 180.167 1.00 56.49  ? 509  ARG A O   1 
ATOM   8604 C CB  . ARG C 2 509 ? 230.861 213.470 179.680 1.00 56.49  ? 509  ARG A CB  1 
ATOM   8605 C CG  . ARG C 2 509 ? 232.222 213.657 179.034 1.00 56.49  ? 509  ARG A CG  1 
ATOM   8606 C CD  . ARG C 2 509 ? 233.262 214.092 180.052 1.00 56.49  ? 509  ARG A CD  1 
ATOM   8607 N NE  . ARG C 2 509 ? 234.601 214.150 179.473 1.00 56.49  ? 509  ARG A NE  1 
ATOM   8608 C CZ  . ARG C 2 509 ? 235.701 214.438 180.161 1.00 56.49  ? 509  ARG A CZ  1 
ATOM   8609 N NH1 . ARG C 2 509 ? 236.878 214.467 179.552 1.00 56.49  ? 509  ARG A NH1 1 
ATOM   8610 N NH2 . ARG C 2 509 ? 235.624 214.696 181.459 1.00 56.49  ? 509  ARG A NH2 1 
ATOM   8611 N N   . VAL C 2 510 ? 228.133 211.327 179.336 1.00 56.62  ? 510  VAL A N   1 
ATOM   8612 C CA  . VAL C 2 510 ? 226.902 210.808 179.917 1.00 56.62  ? 510  VAL A CA  1 
ATOM   8613 C C   . VAL C 2 510 ? 227.246 209.636 180.825 1.00 56.62  ? 510  VAL A C   1 
ATOM   8614 O O   . VAL C 2 510 ? 227.992 208.733 180.428 1.00 56.62  ? 510  VAL A O   1 
ATOM   8615 C CB  . VAL C 2 510 ? 225.896 210.389 178.828 1.00 56.62  ? 510  VAL A CB  1 
ATOM   8616 C CG1 . VAL C 2 510 ? 226.602 209.645 177.708 1.00 56.62  ? 510  VAL A CG1 1 
ATOM   8617 C CG2 . VAL C 2 510 ? 224.782 209.539 179.421 1.00 56.62  ? 510  VAL A CG2 1 
ATOM   8618 N N   . VAL C 2 511 ? 226.711 209.659 182.043 1.00 57.32  ? 511  VAL A N   1 
ATOM   8619 C CA  . VAL C 2 511 ? 226.864 208.566 182.994 1.00 57.32  ? 511  VAL A CA  1 
ATOM   8620 C C   . VAL C 2 511 ? 225.487 207.992 183.296 1.00 57.32  ? 511  VAL A C   1 
ATOM   8621 O O   . VAL C 2 511 ? 224.485 208.713 183.332 1.00 57.32  ? 511  VAL A O   1 
ATOM   8622 C CB  . VAL C 2 511 ? 227.572 209.016 184.291 1.00 57.32  ? 511  VAL A CB  1 
ATOM   8623 C CG1 . VAL C 2 511 ? 228.996 209.452 183.992 1.00 57.32  ? 511  VAL A CG1 1 
ATOM   8624 C CG2 . VAL C 2 511 ? 226.801 210.141 184.957 1.00 57.32  ? 511  VAL A CG2 1 
ATOM   8625 N N   . VAL C 2 512 ? 225.443 206.679 183.504 1.00 57.28  ? 512  VAL A N   1 
ATOM   8626 C CA  . VAL C 2 512 ? 224.201 205.957 183.755 1.00 57.28  ? 512  VAL A CA  1 
ATOM   8627 C C   . VAL C 2 512 ? 224.335 205.234 185.087 1.00 57.28  ? 512  VAL A C   1 
ATOM   8628 O O   . VAL C 2 512 ? 225.243 204.413 185.265 1.00 57.28  ? 512  VAL A O   1 
ATOM   8629 C CB  . VAL C 2 512 ? 223.876 204.967 182.625 1.00 57.28  ? 512  VAL A CB  1 
ATOM   8630 C CG1 . VAL C 2 512 ? 222.597 204.208 182.939 1.00 57.28  ? 512  VAL A CG1 1 
ATOM   8631 C CG2 . VAL C 2 512 ? 223.755 205.698 181.297 1.00 57.28  ? 512  VAL A CG2 1 
ATOM   8632 N N   . LEU C 2 513 ? 223.434 205.538 186.017 1.00 58.59  ? 513  LEU A N   1 
ATOM   8633 C CA  . LEU C 2 513 ? 223.413 204.911 187.334 1.00 58.59  ? 513  LEU A CA  1 
ATOM   8634 C C   . LEU C 2 513 ? 222.326 203.842 187.342 1.00 58.59  ? 513  LEU A C   1 
ATOM   8635 O O   . LEU C 2 513 ? 221.133 204.162 187.361 1.00 58.59  ? 513  LEU A O   1 
ATOM   8636 C CB  . LEU C 2 513 ? 223.173 205.949 188.428 1.00 58.59  ? 513  LEU A CB  1 
ATOM   8637 C CG  . LEU C 2 513 ? 224.198 207.079 188.532 1.00 58.59  ? 513  LEU A CG  1 
ATOM   8638 C CD1 . LEU C 2 513 ? 223.819 208.044 189.643 1.00 58.59  ? 513  LEU A CD1 1 
ATOM   8639 C CD2 . LEU C 2 513 ? 225.593 206.519 188.757 1.00 58.59  ? 513  LEU A CD2 1 
ATOM   8640 N N   . SER C 2 514 ? 222.738 202.578 187.327 1.00 58.80  ? 514  SER A N   1 
ATOM   8641 C CA  . SER C 2 514 ? 221.816 201.450 187.329 1.00 58.80  ? 514  SER A CA  1 
ATOM   8642 C C   . SER C 2 514 ? 221.660 200.937 188.755 1.00 58.80  ? 514  SER A C   1 
ATOM   8643 O O   . SER C 2 514 ? 222.648 200.569 189.399 1.00 58.80  ? 514  SER A O   1 
ATOM   8644 C CB  . SER C 2 514 ? 222.314 200.337 186.407 1.00 58.80  ? 514  SER A CB  1 
ATOM   8645 O OG  . SER C 2 514 ? 221.415 199.242 186.400 1.00 58.80  ? 514  SER A OG  1 
ATOM   8646 N N   . PHE C 2 515 ? 220.422 200.913 189.242 1.00 59.13  ? 515  PHE A N   1 
ATOM   8647 C CA  . PHE C 2 515 ? 220.127 200.443 190.588 1.00 59.13  ? 515  PHE A CA  1 
ATOM   8648 C C   . PHE C 2 515 ? 219.730 198.974 190.545 1.00 59.13  ? 515  PHE A C   1 
ATOM   8649 O O   . PHE C 2 515 ? 218.823 198.590 189.799 1.00 59.13  ? 515  PHE A O   1 
ATOM   8650 C CB  . PHE C 2 515 ? 219.010 201.277 191.216 1.00 59.13  ? 515  PHE A CB  1 
ATOM   8651 C CG  . PHE C 2 515 ? 219.359 202.728 191.387 1.00 59.13  ? 515  PHE A CG  1 
ATOM   8652 C CD1 . PHE C 2 515 ? 220.660 203.112 191.666 1.00 59.13  ? 515  PHE A CD1 1 
ATOM   8653 C CD2 . PHE C 2 515 ? 218.388 203.707 191.265 1.00 59.13  ? 515  PHE A CD2 1 
ATOM   8654 C CE1 . PHE C 2 515 ? 220.984 204.446 191.823 1.00 59.13  ? 515  PHE A CE1 1 
ATOM   8655 C CE2 . PHE C 2 515 ? 218.706 205.042 191.421 1.00 59.13  ? 515  PHE A CE2 1 
ATOM   8656 C CZ  . PHE C 2 515 ? 220.006 205.412 191.701 1.00 59.13  ? 515  PHE A CZ  1 
ATOM   8657 N N   . GLU C 2 516 ? 220.409 198.157 191.345 1.00 65.01  ? 516  GLU A N   1 
ATOM   8658 C CA  . GLU C 2 516 ? 220.156 196.724 191.410 1.00 65.01  ? 516  GLU A CA  1 
ATOM   8659 C C   . GLU C 2 516 ? 219.768 196.346 192.831 1.00 65.01  ? 516  GLU A C   1 
ATOM   8660 O O   . GLU C 2 516 ? 220.440 196.741 193.789 1.00 65.01  ? 516  GLU A O   1 
ATOM   8661 C CB  . GLU C 2 516 ? 221.384 195.924 190.967 1.00 65.01  ? 516  GLU A CB  1 
ATOM   8662 C CG  . GLU C 2 516 ? 221.149 194.422 190.907 1.00 65.01  ? 516  GLU A CG  1 
ATOM   8663 C CD  . GLU C 2 516 ? 222.403 193.648 190.553 1.00 65.01  ? 516  GLU A CD  1 
ATOM   8664 O OE1 . GLU C 2 516 ? 223.510 194.200 190.716 1.00 65.01  ? 516  GLU A OE1 1 
ATOM   8665 O OE2 . GLU C 2 516 ? 222.281 192.487 190.109 1.00 65.01  ? 516  GLU A OE2 1 
ATOM   8666 N N   . LEU C 2 517 ? 218.686 195.583 192.961 1.00 63.37  ? 517  LEU A N   1 
ATOM   8667 C CA  . LEU C 2 517 ? 218.199 195.110 194.251 1.00 63.37  ? 517  LEU A CA  1 
ATOM   8668 C C   . LEU C 2 517 ? 218.145 193.590 194.210 1.00 63.37  ? 517  LEU A C   1 
ATOM   8669 O O   . LEU C 2 517 ? 217.419 193.014 193.393 1.00 63.37  ? 517  LEU A O   1 
ATOM   8670 C CB  . LEU C 2 517 ? 216.822 195.699 194.567 1.00 63.37  ? 517  LEU A CB  1 
ATOM   8671 C CG  . LEU C 2 517 ? 216.462 195.959 196.034 1.00 63.37  ? 517  LEU A CG  1 
ATOM   8672 C CD1 . LEU C 2 517 ? 215.174 196.762 196.125 1.00 63.37  ? 517  LEU A CD1 1 
ATOM   8673 C CD2 . LEU C 2 517 ? 216.337 194.665 196.825 1.00 63.37  ? 517  LEU A CD2 1 
ATOM   8674 N N   . LEU C 2 518 ? 218.911 192.946 195.089 1.00 65.52  ? 518  LEU A N   1 
ATOM   8675 C CA  . LEU C 2 518 ? 218.957 191.490 195.137 1.00 65.52  ? 518  LEU A CA  1 
ATOM   8676 C C   . LEU C 2 518 ? 218.650 190.985 196.540 1.00 65.52  ? 518  LEU A C   1 
ATOM   8677 O O   . LEU C 2 518 ? 218.270 191.765 197.419 1.00 65.52  ? 518  LEU A O   1 
ATOM   8678 C CB  . LEU C 2 518 ? 220.324 190.980 194.678 1.00 65.52  ? 518  LEU A CB  1 
ATOM   8679 C CG  . LEU C 2 518 ? 220.741 191.324 193.247 1.00 65.52  ? 518  LEU A CG  1 
ATOM   8680 C CD1 . LEU C 2 518 ? 222.115 190.752 192.939 1.00 65.52  ? 518  LEU A CD1 1 
ATOM   8681 C CD2 . LEU C 2 518 ? 219.710 190.818 192.251 1.00 65.52  ? 518  LEU A CD2 1 
ATOM   8682 N N   . HIS C 2 519 ? 218.813 189.679 196.759 1.00 72.81  ? 519  HIS A N   1 
ATOM   8683 C CA  . HIS C 2 519 ? 218.568 189.097 198.072 1.00 72.81  ? 519  HIS A CA  1 
ATOM   8684 C C   . HIS C 2 519 ? 219.648 189.452 199.085 1.00 72.81  ? 519  HIS A C   1 
ATOM   8685 O O   . HIS C 2 519 ? 219.454 189.209 200.280 1.00 72.81  ? 519  HIS A O   1 
ATOM   8686 C CB  . HIS C 2 519 ? 218.447 187.577 197.957 1.00 72.81  ? 519  HIS A CB  1 
ATOM   8687 C CG  . HIS C 2 519 ? 217.328 187.124 197.073 1.00 72.81  ? 519  HIS A CG  1 
ATOM   8688 N ND1 . HIS C 2 519 ? 216.360 187.982 196.598 1.00 72.81  ? 519  HIS A ND1 1 
ATOM   8689 C CD2 . HIS C 2 519 ? 217.023 185.902 196.575 1.00 72.81  ? 519  HIS A CD2 1 
ATOM   8690 C CE1 . HIS C 2 519 ? 215.507 187.309 195.846 1.00 72.81  ? 519  HIS A CE1 1 
ATOM   8691 N NE2 . HIS C 2 519 ? 215.887 186.044 195.816 1.00 72.81  ? 519  HIS A NE2 1 
ATOM   8692 N N   . ALA C 2 520 ? 220.769 190.012 198.641 1.00 67.39  ? 520  ALA A N   1 
ATOM   8693 C CA  . ALA C 2 520 ? 221.817 190.416 199.561 1.00 67.39  ? 520  ALA A CA  1 
ATOM   8694 C C   . ALA C 2 520 ? 221.369 191.633 200.370 1.00 67.39  ? 520  ALA A C   1 
ATOM   8695 O O   . ALA C 2 520 ? 220.498 192.390 199.934 1.00 67.39  ? 520  ALA A O   1 
ATOM   8696 C CB  . ALA C 2 520 ? 223.099 190.738 198.799 1.00 67.39  ? 520  ALA A CB  1 
ATOM   8697 N N   . PRO C 2 521 ? 221.935 191.832 201.561 1.00 65.02  ? 521  PRO A N   1 
ATOM   8698 C CA  . PRO C 2 521 ? 221.579 193.015 202.353 1.00 65.02  ? 521  PRO A CA  1 
ATOM   8699 C C   . PRO C 2 521 ? 221.925 194.302 201.620 1.00 65.02  ? 521  PRO A C   1 
ATOM   8700 O O   . PRO C 2 521 ? 222.877 194.365 200.839 1.00 65.02  ? 521  PRO A O   1 
ATOM   8701 C CB  . PRO C 2 521 ? 222.415 192.854 203.627 1.00 65.02  ? 521  PRO A CB  1 
ATOM   8702 C CG  . PRO C 2 521 ? 222.674 191.391 203.723 1.00 65.02  ? 521  PRO A CG  1 
ATOM   8703 C CD  . PRO C 2 521 ? 222.812 190.914 202.308 1.00 65.02  ? 521  PRO A CD  1 
ATOM   8704 N N   . ALA C 2 522 ? 221.131 195.337 201.883 1.00 64.55  ? 522  ALA A N   1 
ATOM   8705 C CA  . ALA C 2 522 ? 221.323 196.624 201.228 1.00 64.55  ? 522  ALA A CA  1 
ATOM   8706 C C   . ALA C 2 522 ? 222.563 197.313 201.783 1.00 64.55  ? 522  ALA A C   1 
ATOM   8707 O O   . ALA C 2 522 ? 222.642 197.595 202.983 1.00 64.55  ? 522  ALA A O   1 
ATOM   8708 C CB  . ALA C 2 522 ? 220.089 197.501 201.419 1.00 64.55  ? 522  ALA A CB  1 
ATOM   8709 N N   . THR C 2 523 ? 223.532 197.584 200.909 1.00 67.05  ? 523  THR A N   1 
ATOM   8710 C CA  . THR C 2 523 ? 224.786 198.215 201.303 1.00 67.05  ? 523  THR A CA  1 
ATOM   8711 C C   . THR C 2 523 ? 224.815 199.711 201.024 1.00 67.05  ? 523  THR A C   1 
ATOM   8712 O O   . THR C 2 523 ? 225.332 200.476 201.843 1.00 67.05  ? 523  THR A O   1 
ATOM   8713 C CB  . THR C 2 523 ? 225.963 197.546 200.587 1.00 67.05  ? 523  THR A CB  1 
ATOM   8714 O OG1 . THR C 2 523 ? 225.802 197.680 199.169 1.00 67.05  ? 523  THR A OG1 1 
ATOM   8715 C CG2 . THR C 2 523 ? 226.035 196.070 200.946 1.00 67.05  ? 523  THR A CG2 1 
ATOM   8716 N N   . VAL C 2 524 ? 224.276 200.147 199.890 1.00 65.91  ? 524  VAL A N   1 
ATOM   8717 C CA  . VAL C 2 524 ? 224.258 201.557 199.517 1.00 65.91  ? 524  VAL A CA  1 
ATOM   8718 C C   . VAL C 2 524 ? 222.886 202.127 199.851 1.00 65.91  ? 524  VAL A C   1 
ATOM   8719 O O   . VAL C 2 524 ? 221.861 201.636 199.362 1.00 65.91  ? 524  VAL A O   1 
ATOM   8720 C CB  . VAL C 2 524 ? 224.603 201.752 198.032 1.00 65.91  ? 524  VAL A CB  1 
ATOM   8721 C CG1 . VAL C 2 524 ? 223.905 200.709 197.171 1.00 65.91  ? 524  VAL A CG1 1 
ATOM   8722 C CG2 . VAL C 2 524 ? 224.233 203.158 197.581 1.00 65.91  ? 524  VAL A CG2 1 
ATOM   8723 N N   . CYS C 2 525 ? 222.865 203.156 200.693 1.00 70.02  ? 525  CYS A N   1 
ATOM   8724 C CA  . CYS C 2 525 ? 221.642 203.833 201.099 1.00 70.02  ? 525  CYS A CA  1 
ATOM   8725 C C   . CYS C 2 525 ? 221.824 205.336 200.925 1.00 70.02  ? 525  CYS A C   1 
ATOM   8726 O O   . CYS C 2 525 ? 222.870 205.811 200.471 1.00 70.02  ? 525  CYS A O   1 
ATOM   8727 C CB  . CYS C 2 525 ? 221.275 203.503 202.551 1.00 70.02  ? 525  CYS A CB  1 
ATOM   8728 S SG  . CYS C 2 525 ? 220.830 201.782 202.884 1.00 70.02  ? 525  CYS A SG  1 
ATOM   8729 N N   . GLY C 2 526 ? 220.792 206.088 201.293 1.00 69.65  ? 526  GLY A N   1 
ATOM   8730 C CA  . GLY C 2 526 ? 220.853 207.528 201.269 1.00 69.65  ? 526  GLY A CA  1 
ATOM   8731 C C   . GLY C 2 526 ? 221.320 208.085 202.597 1.00 69.65  ? 526  GLY A C   1 
ATOM   8732 O O   . GLY C 2 526 ? 221.151 207.462 203.650 1.00 69.65  ? 526  GLY A O   1 
ATOM   8733 N N   . PRO C 2 527 ? 221.929 209.273 202.573 1.00 69.79  ? 527  PRO A N   1 
ATOM   8734 C CA  . PRO C 2 527 ? 222.409 209.880 203.821 1.00 69.79  ? 527  PRO A CA  1 
ATOM   8735 C C   . PRO C 2 527 ? 221.275 210.211 204.776 1.00 69.79  ? 527  PRO A C   1 
ATOM   8736 O O   . PRO C 2 527 ? 220.432 211.065 204.482 1.00 69.79  ? 527  PRO A O   1 
ATOM   8737 C CB  . PRO C 2 527 ? 223.127 211.150 203.343 1.00 69.79  ? 527  PRO A CB  1 
ATOM   8738 C CG  . PRO C 2 527 ? 223.435 210.901 201.904 1.00 69.79  ? 527  PRO A CG  1 
ATOM   8739 C CD  . PRO C 2 527 ? 222.300 210.070 201.393 1.00 69.79  ? 527  PRO A CD  1 
ATOM   8740 N N   . LYS C 2 528 ? 221.245 209.538 205.922 1.00 67.07  ? 528  LYS A N   1 
ATOM   8741 C CA  . LYS C 2 528 ? 220.209 209.784 206.915 1.00 67.07  ? 528  LYS A CA  1 
ATOM   8742 C C   . LYS C 2 528 ? 220.483 211.103 207.626 1.00 67.07  ? 528  LYS A C   1 
ATOM   8743 O O   . LYS C 2 528 ? 221.522 211.262 208.276 1.00 67.07  ? 528  LYS A O   1 
ATOM   8744 C CB  . LYS C 2 528 ? 220.153 208.631 207.913 1.00 67.07  ? 528  LYS A CB  1 
ATOM   8745 C CG  . LYS C 2 528 ? 219.952 207.270 207.267 1.00 67.07  ? 528  LYS A CG  1 
ATOM   8746 C CD  . LYS C 2 528 ? 219.975 206.157 208.300 1.00 67.07  ? 528  LYS A CD  1 
ATOM   8747 C CE  . LYS C 2 528 ? 219.813 204.795 207.646 1.00 67.07  ? 528  LYS A CE  1 
ATOM   8748 N NZ  . LYS C 2 528 ? 218.531 204.690 206.897 1.00 67.07  ? 528  LYS A NZ  1 
ATOM   8749 N N   . LYS C 2 529 ? 219.556 212.048 207.499 1.00 68.80  ? 529  LYS A N   1 
ATOM   8750 C CA  . LYS C 2 529 ? 219.734 213.357 208.108 1.00 68.80  ? 529  LYS A CA  1 
ATOM   8751 C C   . LYS C 2 529 ? 219.660 213.260 209.627 1.00 68.80  ? 529  LYS A C   1 
ATOM   8752 O O   . LYS C 2 529 ? 219.008 212.376 210.188 1.00 68.80  ? 529  LYS A O   1 
ATOM   8753 C CB  . LYS C 2 529 ? 218.679 214.334 207.593 1.00 68.80  ? 529  LYS A CB  1 
ATOM   8754 C CG  . LYS C 2 529 ? 218.733 214.572 206.093 1.00 68.80  ? 529  LYS A CG  1 
ATOM   8755 C CD  . LYS C 2 529 ? 217.672 215.566 205.653 1.00 68.80  ? 529  LYS A CD  1 
ATOM   8756 C CE  . LYS C 2 529 ? 216.275 215.069 205.990 1.00 68.80  ? 529  LYS A CE  1 
ATOM   8757 N NZ  . LYS C 2 529 ? 215.972 213.773 205.324 1.00 68.80  ? 529  LYS A NZ  1 
ATOM   8758 N N   . SER C 2 530 ? 220.342 214.188 210.293 1.00 68.49  ? 530  SER A N   1 
ATOM   8759 C CA  . SER C 2 530 ? 220.391 214.233 211.746 1.00 68.49  ? 530  SER A CA  1 
ATOM   8760 C C   . SER C 2 530 ? 219.932 215.601 212.228 1.00 68.49  ? 530  SER A C   1 
ATOM   8761 O O   . SER C 2 530 ? 220.265 216.625 211.625 1.00 68.49  ? 530  SER A O   1 
ATOM   8762 C CB  . SER C 2 530 ? 221.803 213.941 212.266 1.00 68.49  ? 530  SER A CB  1 
ATOM   8763 O OG  . SER C 2 530 ? 221.847 213.995 213.681 1.00 68.49  ? 530  SER A OG  1 
ATOM   8764 N N   . THR C 2 531 ? 219.168 215.610 213.314 1.00 69.11  ? 531  THR A N   1 
ATOM   8765 C CA  . THR C 2 531 ? 218.656 216.832 213.911 1.00 69.11  ? 531  THR A CA  1 
ATOM   8766 C C   . THR C 2 531 ? 219.365 217.106 215.231 1.00 69.11  ? 531  THR A C   1 
ATOM   8767 O O   . THR C 2 531 ? 220.109 216.272 215.754 1.00 69.11  ? 531  THR A O   1 
ATOM   8768 C CB  . THR C 2 531 ? 217.141 216.741 214.129 1.00 69.11  ? 531  THR A CB  1 
ATOM   8769 O OG1 . THR C 2 531 ? 216.852 215.666 215.031 1.00 69.11  ? 531  THR A OG1 1 
ATOM   8770 C CG2 . THR C 2 531 ? 216.428 216.492 212.808 1.00 69.11  ? 531  THR A CG2 1 
ATOM   8771 N N   . ASN C 2 532 ? 219.123 218.297 215.769 1.00 69.81  ? 532  ASN A N   1 
ATOM   8772 C CA  . ASN C 2 532 ? 219.755 218.706 217.013 1.00 69.81  ? 532  ASN A CA  1 
ATOM   8773 C C   . ASN C 2 532 ? 219.071 218.054 218.208 1.00 69.81  ? 532  ASN A C   1 
ATOM   8774 O O   . ASN C 2 532 ? 217.896 217.681 218.155 1.00 69.81  ? 532  ASN A O   1 
ATOM   8775 C CB  . ASN C 2 532 ? 219.720 220.227 217.158 1.00 69.81  ? 532  ASN A CB  1 
ATOM   8776 C CG  . ASN C 2 532 ? 220.466 220.935 216.045 1.00 69.81  ? 532  ASN A CG  1 
ATOM   8777 O OD1 . ASN C 2 532 ? 221.421 220.398 215.483 1.00 69.81  ? 532  ASN A OD1 1 
ATOM   8778 N ND2 . ASN C 2 532 ? 220.034 222.148 215.720 1.00 69.81  ? 532  ASN A ND2 1 
ATOM   8779 N N   . LEU C 2 533 ? 219.826 217.919 219.294 1.00 70.67  ? 533  LEU A N   1 
ATOM   8780 C CA  . LEU C 2 533 ? 219.305 217.331 220.517 1.00 70.67  ? 533  LEU A CA  1 
ATOM   8781 C C   . LEU C 2 533 ? 218.546 218.370 221.336 1.00 70.67  ? 533  LEU A C   1 
ATOM   8782 O O   . LEU C 2 533 ? 218.640 219.578 221.105 1.00 70.67  ? 533  LEU A O   1 
ATOM   8783 C CB  . LEU C 2 533 ? 220.437 216.735 221.354 1.00 70.67  ? 533  LEU A CB  1 
ATOM   8784 C CG  . LEU C 2 533 ? 221.023 215.404 220.884 1.00 70.67  ? 533  LEU A CG  1 
ATOM   8785 C CD1 . LEU C 2 533 ? 222.251 215.046 221.703 1.00 70.67  ? 533  LEU A CD1 1 
ATOM   8786 C CD2 . LEU C 2 533 ? 219.977 214.308 220.981 1.00 70.67  ? 533  LEU A CD2 1 
ATOM   8787 N N   . VAL C 2 534 ? 217.785 217.877 222.308 1.00 76.49  ? 534  VAL A N   1 
ATOM   8788 C CA  . VAL C 2 534 ? 217.035 218.729 223.224 1.00 76.49  ? 534  VAL A CA  1 
ATOM   8789 C C   . VAL C 2 534 ? 216.886 217.987 224.544 1.00 76.49  ? 534  VAL A C   1 
ATOM   8790 O O   . VAL C 2 534 ? 216.656 216.774 224.568 1.00 76.49  ? 534  VAL A O   1 
ATOM   8791 C CB  . VAL C 2 534 ? 215.666 219.130 222.630 1.00 76.49  ? 534  VAL A CB  1 
ATOM   8792 C CG1 . VAL C 2 534 ? 214.854 217.896 222.262 1.00 76.49  ? 534  VAL A CG1 1 
ATOM   8793 C CG2 . VAL C 2 534 ? 214.901 220.020 223.598 1.00 76.49  ? 534  VAL A CG2 1 
ATOM   8794 N N   . LYS C 2 535 ? 217.036 218.717 225.646 1.00 79.42  ? 535  LYS A N   1 
ATOM   8795 C CA  . LYS C 2 535 ? 217.007 218.135 226.977 1.00 79.42  ? 535  LYS A CA  1 
ATOM   8796 C C   . LYS C 2 535 ? 215.837 218.695 227.775 1.00 79.42  ? 535  LYS A C   1 
ATOM   8797 O O   . LYS C 2 535 ? 215.400 219.829 227.556 1.00 79.42  ? 535  LYS A O   1 
ATOM   8798 C CB  . LYS C 2 535 ? 218.319 218.401 227.725 1.00 79.42  ? 535  LYS A CB  1 
ATOM   8799 C CG  . LYS C 2 535 ? 219.567 218.063 226.924 1.00 79.42  ? 535  LYS A CG  1 
ATOM   8800 C CD  . LYS C 2 535 ? 219.579 216.603 226.505 1.00 79.42  ? 535  LYS A CD  1 
ATOM   8801 C CE  . LYS C 2 535 ? 220.789 216.290 225.639 1.00 79.42  ? 535  LYS A CE  1 
ATOM   8802 N NZ  . LYS C 2 535 ? 222.067 216.583 226.343 1.00 79.42  ? 535  LYS A NZ  1 
ATOM   8803 N N   . ASN C 2 536 ? 215.332 217.875 228.700 1.00 86.42  ? 536  ASN A N   1 
ATOM   8804 C CA  . ASN C 2 536 ? 214.280 218.273 229.637 1.00 86.42  ? 536  ASN A CA  1 
ATOM   8805 C C   . ASN C 2 536 ? 212.997 218.679 228.914 1.00 86.42  ? 536  ASN A C   1 
ATOM   8806 O O   . ASN C 2 536 ? 212.295 219.603 229.329 1.00 86.42  ? 536  ASN A O   1 
ATOM   8807 C CB  . ASN C 2 536 ? 214.762 219.395 230.562 1.00 86.42  ? 536  ASN A CB  1 
ATOM   8808 C CG  . ASN C 2 536 ? 215.994 219.006 231.354 1.00 86.42  ? 536  ASN A CG  1 
ATOM   8809 O OD1 . ASN C 2 536 ? 217.123 219.216 230.911 1.00 86.42  ? 536  ASN A OD1 1 
ATOM   8810 N ND2 . ASN C 2 536 ? 215.783 218.433 232.534 1.00 86.42  ? 536  ASN A ND2 1 
ATOM   8811 N N   . LYS C 2 537 ? 212.683 217.979 227.825 1.00 85.84  ? 537  LYS A N   1 
ATOM   8812 C CA  . LYS C 2 537 ? 211.451 218.208 227.083 1.00 85.84  ? 537  LYS A CA  1 
ATOM   8813 C C   . LYS C 2 537 ? 210.903 216.880 226.585 1.00 85.84  ? 537  LYS A C   1 
ATOM   8814 O O   . LYS C 2 537 ? 211.666 215.982 226.221 1.00 85.84  ? 537  LYS A O   1 
ATOM   8815 C CB  . LYS C 2 537 ? 211.668 219.158 225.895 1.00 85.84  ? 537  LYS A CB  1 
ATOM   8816 C CG  . LYS C 2 537 ? 211.994 220.591 226.286 1.00 85.84  ? 537  LYS A CG  1 
ATOM   8817 C CD  . LYS C 2 537 ? 211.904 221.528 225.094 1.00 85.84  ? 537  LYS A CD  1 
ATOM   8818 C CE  . LYS C 2 537 ? 210.488 221.580 224.543 1.00 85.84  ? 537  LYS A CE  1 
ATOM   8819 N NZ  . LYS C 2 537 ? 210.367 222.542 223.412 1.00 85.84  ? 537  LYS A NZ  1 
ATOM   8820 N N   . CYS C 2 538 ? 209.576 216.762 226.575 1.00 89.05  ? 538  CYS A N   1 
ATOM   8821 C CA  . CYS C 2 538 ? 208.901 215.562 226.084 1.00 89.05  ? 538  CYS A CA  1 
ATOM   8822 C C   . CYS C 2 538 ? 208.960 215.575 224.561 1.00 89.05  ? 538  CYS A C   1 
ATOM   8823 O O   . CYS C 2 538 ? 208.238 216.328 223.904 1.00 89.05  ? 538  CYS A O   1 
ATOM   8824 C CB  . CYS C 2 538 ? 207.463 215.511 226.590 1.00 89.05  ? 538  CYS A CB  1 
ATOM   8825 S SG  . CYS C 2 538 ? 206.587 213.971 226.225 1.00 89.05  ? 538  CYS A SG  1 
ATOM   8826 N N   . VAL C 2 539 ? 209.825 214.737 223.994 1.00 80.78  ? 539  VAL A N   1 
ATOM   8827 C CA  . VAL C 2 539 ? 210.094 214.736 222.560 1.00 80.78  ? 539  VAL A CA  1 
ATOM   8828 C C   . VAL C 2 539 ? 210.216 213.298 222.076 1.00 80.78  ? 539  VAL A C   1 
ATOM   8829 O O   . VAL C 2 539 ? 210.831 212.457 222.740 1.00 80.78  ? 539  VAL A O   1 
ATOM   8830 C CB  . VAL C 2 539 ? 211.369 215.544 222.232 1.00 80.78  ? 539  VAL A CB  1 
ATOM   8831 C CG1 . VAL C 2 539 ? 212.520 215.115 223.131 1.00 80.78  ? 539  VAL A CG1 1 
ATOM   8832 C CG2 . VAL C 2 539 ? 211.749 215.392 220.768 1.00 80.78  ? 539  VAL A CG2 1 
ATOM   8833 N N   . ASN C 2 540 ? 209.618 213.014 220.921 1.00 76.25  ? 540  ASN A N   1 
ATOM   8834 C CA  . ASN C 2 540 ? 209.773 211.714 220.286 1.00 76.25  ? 540  ASN A CA  1 
ATOM   8835 C C   . ASN C 2 540 ? 211.122 211.637 219.583 1.00 76.25  ? 540  ASN A C   1 
ATOM   8836 O O   . ASN C 2 540 ? 211.559 212.595 218.939 1.00 76.25  ? 540  ASN A O   1 
ATOM   8837 C CB  . ASN C 2 540 ? 208.639 211.461 219.292 1.00 76.25  ? 540  ASN A CB  1 
ATOM   8838 C CG  . ASN C 2 540 ? 208.525 212.554 218.247 1.00 76.25  ? 540  ASN A CG  1 
ATOM   8839 O OD1 . ASN C 2 540 ? 209.168 212.496 217.199 1.00 76.25  ? 540  ASN A OD1 1 
ATOM   8840 N ND2 . ASN C 2 540 ? 207.700 213.556 218.527 1.00 76.25  ? 540  ASN A ND2 1 
ATOM   8841 N N   . PHE C 2 541 ? 211.782 210.489 219.709 1.00 72.21  ? 541  PHE A N   1 
ATOM   8842 C CA  . PHE C 2 541 ? 213.150 210.322 219.246 1.00 72.21  ? 541  PHE A CA  1 
ATOM   8843 C C   . PHE C 2 541 ? 213.262 209.138 218.293 1.00 72.21  ? 541  PHE A C   1 
ATOM   8844 O O   . PHE C 2 541 ? 212.385 208.273 218.230 1.00 72.21  ? 541  PHE A O   1 
ATOM   8845 C CB  . PHE C 2 541 ? 214.109 210.130 220.429 1.00 72.21  ? 541  PHE A CB  1 
ATOM   8846 C CG  . PHE C 2 541 ? 213.675 209.063 221.395 1.00 72.21  ? 541  PHE A CG  1 
ATOM   8847 C CD1 . PHE C 2 541 ? 214.041 207.742 221.201 1.00 72.21  ? 541  PHE A CD1 1 
ATOM   8848 C CD2 . PHE C 2 541 ? 212.903 209.384 222.499 1.00 72.21  ? 541  PHE A CD2 1 
ATOM   8849 C CE1 . PHE C 2 541 ? 213.642 206.760 222.088 1.00 72.21  ? 541  PHE A CE1 1 
ATOM   8850 C CE2 . PHE C 2 541 ? 212.502 208.406 223.390 1.00 72.21  ? 541  PHE A CE2 1 
ATOM   8851 C CZ  . PHE C 2 541 ? 212.872 207.093 223.183 1.00 72.21  ? 541  PHE A CZ  1 
ATOM   8852 N N   . ASN C 2 542 ? 214.369 209.118 217.547 1.00 68.75  ? 542  ASN A N   1 
ATOM   8853 C CA  . ASN C 2 542 ? 214.668 208.011 216.638 1.00 68.75  ? 542  ASN A CA  1 
ATOM   8854 C C   . ASN C 2 542 ? 216.183 207.995 216.429 1.00 68.75  ? 542  ASN A C   1 
ATOM   8855 O O   . ASN C 2 542 ? 216.710 208.813 215.671 1.00 68.75  ? 542  ASN A O   1 
ATOM   8856 C CB  . ASN C 2 542 ? 213.923 208.161 215.322 1.00 68.75  ? 542  ASN A CB  1 
ATOM   8857 C CG  . ASN C 2 542 ? 214.244 207.050 214.342 1.00 68.75  ? 542  ASN A CG  1 
ATOM   8858 O OD1 . ASN C 2 542 ? 214.607 205.942 214.738 1.00 68.75  ? 542  ASN A OD1 1 
ATOM   8859 N ND2 . ASN C 2 542 ? 214.113 207.341 213.053 1.00 68.75  ? 542  ASN A ND2 1 
ATOM   8860 N N   . PHE C 2 543 ? 216.865 207.069 217.103 1.00 68.81  ? 543  PHE A N   1 
ATOM   8861 C CA  . PHE C 2 543 ? 218.320 206.985 217.006 1.00 68.81  ? 543  PHE A CA  1 
ATOM   8862 C C   . PHE C 2 543 ? 218.755 205.988 215.933 1.00 68.81  ? 543  PHE A C   1 
ATOM   8863 O O   . PHE C 2 543 ? 219.371 206.371 214.935 1.00 68.81  ? 543  PHE A O   1 
ATOM   8864 C CB  . PHE C 2 543 ? 218.912 206.614 218.371 1.00 68.81  ? 543  PHE A CB  1 
ATOM   8865 C CG  . PHE C 2 543 ? 218.738 207.681 219.415 1.00 68.81  ? 543  PHE A CG  1 
ATOM   8866 C CD1 . PHE C 2 543 ? 217.564 207.773 220.144 1.00 68.81  ? 543  PHE A CD1 1 
ATOM   8867 C CD2 . PHE C 2 543 ? 219.749 208.593 219.669 1.00 68.81  ? 543  PHE A CD2 1 
ATOM   8868 C CE1 . PHE C 2 543 ? 217.401 208.754 221.103 1.00 68.81  ? 543  PHE A CE1 1 
ATOM   8869 C CE2 . PHE C 2 543 ? 219.592 209.576 220.629 1.00 68.81  ? 543  PHE A CE2 1 
ATOM   8870 C CZ  . PHE C 2 543 ? 218.417 209.656 221.346 1.00 68.81  ? 543  PHE A CZ  1 
ATOM   8871 N N   . ASN C 2 544 ? 218.451 204.709 216.128 1.00 70.78  ? 544  ASN A N   1 
ATOM   8872 C CA  . ASN C 2 544 ? 218.684 203.705 215.097 1.00 70.78  ? 544  ASN A CA  1 
ATOM   8873 C C   . ASN C 2 544 ? 217.398 203.043 214.633 1.00 70.78  ? 544  ASN A C   1 
ATOM   8874 O O   . ASN C 2 544 ? 217.119 203.011 213.428 1.00 70.78  ? 544  ASN A O   1 
ATOM   8875 C CB  . ASN C 2 544 ? 219.671 202.643 215.606 1.00 70.78  ? 544  ASN A CB  1 
ATOM   8876 C CG  . ASN C 2 544 ? 221.048 203.213 215.877 1.00 70.78  ? 544  ASN A CG  1 
ATOM   8877 O OD1 . ASN C 2 544 ? 221.352 203.627 216.995 1.00 70.78  ? 544  ASN A OD1 1 
ATOM   8878 N ND2 . ASN C 2 544 ? 221.889 203.244 214.849 1.00 70.78  ? 544  ASN A ND2 1 
ATOM   8879 N N   . GLY C 2 545 ? 216.606 202.513 215.559 1.00 73.39  ? 545  GLY A N   1 
ATOM   8880 C CA  . GLY C 2 545 ? 215.316 201.940 215.235 1.00 73.39  ? 545  GLY A CA  1 
ATOM   8881 C C   . GLY C 2 545 ? 214.328 202.142 216.362 1.00 73.39  ? 545  GLY A C   1 
ATOM   8882 O O   . GLY C 2 545 ? 213.180 201.692 216.289 1.00 73.39  ? 545  GLY A O   1 
ATOM   8883 N N   . LEU C 2 546 ? 214.771 202.822 217.417 1.00 69.29  ? 546  LEU A N   1 
ATOM   8884 C CA  . LEU C 2 546 ? 213.950 203.037 218.603 1.00 69.29  ? 546  LEU A CA  1 
ATOM   8885 C C   . LEU C 2 546 ? 213.053 204.245 218.367 1.00 69.29  ? 546  LEU A C   1 
ATOM   8886 O O   . LEU C 2 546 ? 213.534 205.378 218.275 1.00 69.29  ? 546  LEU A O   1 
ATOM   8887 C CB  . LEU C 2 546 ? 214.826 203.237 219.837 1.00 69.29  ? 546  LEU A CB  1 
ATOM   8888 C CG  . LEU C 2 546 ? 215.666 202.058 220.339 1.00 69.29  ? 546  LEU A CG  1 
ATOM   8889 C CD1 . LEU C 2 546 ? 216.942 201.886 219.525 1.00 69.29  ? 546  LEU A CD1 1 
ATOM   8890 C CD2 . LEU C 2 546 ? 215.993 202.223 221.815 1.00 69.29  ? 546  LEU A CD2 1 
ATOM   8891 N N   . THR C 2 547 ? 211.750 204.005 218.268 1.00 73.23  ? 547  THR A N   1 
ATOM   8892 C CA  . THR C 2 547 ? 210.760 205.057 218.057 1.00 73.23  ? 547  THR A CA  1 
ATOM   8893 C C   . THR C 2 547 ? 209.948 205.187 219.344 1.00 73.23  ? 547  THR A C   1 
ATOM   8894 O O   . THR C 2 547 ? 208.894 204.569 219.498 1.00 73.23  ? 547  THR A O   1 
ATOM   8895 C CB  . THR C 2 547 ? 209.868 204.743 216.858 1.00 73.23  ? 547  THR A CB  1 
ATOM   8896 O OG1 . THR C 2 547 ? 209.177 203.509 217.085 1.00 73.23  ? 547  THR A OG1 1 
ATOM   8897 C CG2 . THR C 2 547 ? 210.704 204.623 215.593 1.00 73.23  ? 547  THR A CG2 1 
ATOM   8898 N N   . GLY C 2 548 ? 210.451 205.999 220.269 1.00 73.19  ? 548  GLY A N   1 
ATOM   8899 C CA  . GLY C 2 548 ? 209.773 206.222 221.529 1.00 73.19  ? 548  GLY A CA  1 
ATOM   8900 C C   . GLY C 2 548 ? 209.442 207.679 221.767 1.00 73.19  ? 548  GLY A C   1 
ATOM   8901 O O   . GLY C 2 548 ? 209.628 208.516 220.879 1.00 73.19  ? 548  GLY A O   1 
ATOM   8902 N N   . THR C 2 549 ? 208.950 207.996 222.962 1.00 78.36  ? 549  THR A N   1 
ATOM   8903 C CA  . THR C 2 549 ? 208.601 209.369 223.311 1.00 78.36  ? 549  THR A CA  1 
ATOM   8904 C C   . THR C 2 549 ? 208.875 209.575 224.791 1.00 78.36  ? 549  THR A C   1 
ATOM   8905 O O   . THR C 2 549 ? 208.304 208.874 225.631 1.00 78.36  ? 549  THR A O   1 
ATOM   8906 C CB  . THR C 2 549 ? 207.136 209.670 222.988 1.00 78.36  ? 549  THR A CB  1 
ATOM   8907 O OG1 . THR C 2 549 ? 206.913 209.519 221.580 1.00 78.36  ? 549  THR A OG1 1 
ATOM   8908 C CG2 . THR C 2 549 ? 206.779 211.089 223.403 1.00 78.36  ? 549  THR A CG2 1 
ATOM   8909 N N   . GLY C 2 550 ? 209.743 210.529 225.106 1.00 81.16  ? 550  GLY A N   1 
ATOM   8910 C CA  . GLY C 2 550 ? 210.076 210.793 226.490 1.00 81.16  ? 550  GLY A CA  1 
ATOM   8911 C C   . GLY C 2 550 ? 210.983 211.997 226.604 1.00 81.16  ? 550  GLY A C   1 
ATOM   8912 O O   . GLY C 2 550 ? 211.184 212.742 225.642 1.00 81.16  ? 550  GLY A O   1 
ATOM   8913 N N   . VAL C 2 551 ? 211.529 212.177 227.803 1.00 80.80  ? 551  VAL A N   1 
ATOM   8914 C CA  . VAL C 2 551 ? 212.438 213.277 228.103 1.00 80.80  ? 551  VAL A CA  1 
ATOM   8915 C C   . VAL C 2 551 ? 213.857 212.729 228.167 1.00 80.80  ? 551  VAL A C   1 
ATOM   8916 O O   . VAL C 2 551 ? 214.125 211.757 228.885 1.00 80.80  ? 551  VAL A O   1 
ATOM   8917 C CB  . VAL C 2 551 ? 212.050 213.977 229.417 1.00 80.80  ? 551  VAL A CB  1 
ATOM   8918 C CG1 . VAL C 2 551 ? 211.628 212.957 230.462 1.00 80.80  ? 551  VAL A CG1 1 
ATOM   8919 C CG2 . VAL C 2 551 ? 213.205 214.818 229.933 1.00 80.80  ? 551  VAL A CG2 1 
ATOM   8920 N N   . LEU C 2 552 ? 214.763 213.344 227.412 1.00 77.26  ? 552  LEU A N   1 
ATOM   8921 C CA  . LEU C 2 552 ? 216.152 212.912 227.342 1.00 77.26  ? 552  LEU A CA  1 
ATOM   8922 C C   . LEU C 2 552 ? 216.997 213.784 228.263 1.00 77.26  ? 552  LEU A C   1 
ATOM   8923 O O   . LEU C 2 552 ? 217.042 215.008 228.099 1.00 77.26  ? 552  LEU A O   1 
ATOM   8924 C CB  . LEU C 2 552 ? 216.676 212.983 225.908 1.00 77.26  ? 552  LEU A CB  1 
ATOM   8925 C CG  . LEU C 2 552 ? 215.943 212.129 224.874 1.00 77.26  ? 552  LEU A CG  1 
ATOM   8926 C CD1 . LEU C 2 552 ? 216.679 212.158 223.545 1.00 77.26  ? 552  LEU A CD1 1 
ATOM   8927 C CD2 . LEU C 2 552 ? 215.781 210.702 225.370 1.00 77.26  ? 552  LEU A CD2 1 
ATOM   8928 N N   . THR C 2 553 ? 217.663 213.152 229.226 1.00 77.28  ? 553  THR A N   1 
ATOM   8929 C CA  . THR C 2 553 ? 218.541 213.841 230.156 1.00 77.28  ? 553  THR A CA  1 
ATOM   8930 C C   . THR C 2 553 ? 219.871 213.105 230.232 1.00 77.28  ? 553  THR A C   1 
ATOM   8931 O O   . THR C 2 553 ? 219.987 211.944 229.832 1.00 77.28  ? 553  THR A O   1 
ATOM   8932 C CB  . THR C 2 553 ? 217.918 213.945 231.556 1.00 77.28  ? 553  THR A CB  1 
ATOM   8933 O OG1 . THR C 2 553 ? 218.842 214.580 232.448 1.00 77.28  ? 553  THR A OG1 1 
ATOM   8934 C CG2 . THR C 2 553 ? 217.572 212.563 232.089 1.00 77.28  ? 553  THR A CG2 1 
ATOM   8935 N N   . GLU C 2 554 ? 220.881 213.799 230.750 1.00 79.83  ? 554  GLU A N   1 
ATOM   8936 C CA  . GLU C 2 554 ? 222.200 213.199 230.888 1.00 79.83  ? 554  GLU A CA  1 
ATOM   8937 C C   . GLU C 2 554 ? 222.189 212.138 231.981 1.00 79.83  ? 554  GLU A C   1 
ATOM   8938 O O   . GLU C 2 554 ? 221.535 212.293 233.016 1.00 79.83  ? 554  GLU A O   1 
ATOM   8939 C CB  . GLU C 2 554 ? 223.244 214.270 231.202 1.00 79.83  ? 554  GLU A CB  1 
ATOM   8940 C CG  . GLU C 2 554 ? 223.438 215.288 230.090 1.00 79.83  ? 554  GLU A CG  1 
ATOM   8941 C CD  . GLU C 2 554 ? 224.520 216.299 230.408 1.00 79.83  ? 554  GLU A CD  1 
ATOM   8942 O OE1 . GLU C 2 554 ? 225.110 216.215 231.506 1.00 79.83  ? 554  GLU A OE1 1 
ATOM   8943 O OE2 . GLU C 2 554 ? 224.781 217.179 229.561 1.00 79.83  ? 554  GLU A OE2 1 
ATOM   8944 N N   . SER C 2 555 ? 222.920 211.055 231.745 1.00 77.79  ? 555  SER A N   1 
ATOM   8945 C CA  . SER C 2 555 ? 222.962 209.917 232.648 1.00 77.79  ? 555  SER A CA  1 
ATOM   8946 C C   . SER C 2 555 ? 224.309 209.849 233.357 1.00 77.79  ? 555  SER A C   1 
ATOM   8947 O O   . SER C 2 555 ? 225.264 210.549 233.010 1.00 77.79  ? 555  SER A O   1 
ATOM   8948 C CB  . SER C 2 555 ? 222.696 208.612 231.889 1.00 77.79  ? 555  SER A CB  1 
ATOM   8949 O OG  . SER C 2 555 ? 222.728 207.498 232.765 1.00 77.79  ? 555  SER A OG  1 
ATOM   8950 N N   . ASN C 2 556 ? 224.371 208.982 234.366 1.00 79.05  ? 556  ASN A N   1 
ATOM   8951 C CA  . ASN C 2 556 ? 225.588 208.756 235.132 1.00 79.05  ? 556  ASN A CA  1 
ATOM   8952 C C   . ASN C 2 556 ? 226.145 207.352 234.954 1.00 79.05  ? 556  ASN A C   1 
ATOM   8953 O O   . ASN C 2 556 ? 227.132 207.003 235.610 1.00 79.05  ? 556  ASN A O   1 
ATOM   8954 C CB  . ASN C 2 556 ? 225.334 209.026 236.620 1.00 79.05  ? 556  ASN A CB  1 
ATOM   8955 C CG  . ASN C 2 556 ? 224.224 208.165 237.186 1.00 79.05  ? 556  ASN A CG  1 
ATOM   8956 O OD1 . ASN C 2 556 ? 223.293 207.786 236.476 1.00 79.05  ? 556  ASN A OD1 1 
ATOM   8957 N ND2 . ASN C 2 556 ? 224.316 207.850 238.473 1.00 79.05  ? 556  ASN A ND2 1 
ATOM   8958 N N   . LYS C 2 557 ? 225.545 206.540 234.090 1.00 74.20  ? 557  LYS A N   1 
ATOM   8959 C CA  . LYS C 2 557 ? 226.025 205.193 233.834 1.00 74.20  ? 557  LYS A CA  1 
ATOM   8960 C C   . LYS C 2 557 ? 226.991 205.188 232.652 1.00 74.20  ? 557  LYS A C   1 
ATOM   8961 O O   . LYS C 2 557 ? 227.183 206.192 231.964 1.00 74.20  ? 557  LYS A O   1 
ATOM   8962 C CB  . LYS C 2 557 ? 224.853 204.247 233.574 1.00 74.20  ? 557  LYS A CB  1 
ATOM   8963 C CG  . LYS C 2 557 ? 223.890 204.119 234.743 1.00 74.20  ? 557  LYS A CG  1 
ATOM   8964 C CD  . LYS C 2 557 ? 222.724 203.206 234.402 1.00 74.20  ? 557  LYS A CD  1 
ATOM   8965 C CE  . LYS C 2 557 ? 221.910 203.759 233.245 1.00 74.20  ? 557  LYS A CE  1 
ATOM   8966 N NZ  . LYS C 2 557 ? 220.749 202.887 232.917 1.00 74.20  ? 557  LYS A NZ  1 
ATOM   8967 N N   . LYS C 2 558 ? 227.612 204.032 232.424 1.00 72.73  ? 558  LYS A N   1 
ATOM   8968 C CA  . LYS C 2 558 ? 228.563 203.853 231.334 1.00 72.73  ? 558  LYS A CA  1 
ATOM   8969 C C   . LYS C 2 558 ? 228.238 202.556 230.611 1.00 72.73  ? 558  LYS A C   1 
ATOM   8970 O O   . LYS C 2 558 ? 228.247 201.484 231.223 1.00 72.73  ? 558  LYS A O   1 
ATOM   8971 C CB  . LYS C 2 558 ? 230.008 203.833 231.846 1.00 72.73  ? 558  LYS A CB  1 
ATOM   8972 C CG  . LYS C 2 558 ? 230.523 205.171 232.360 1.00 72.73  ? 558  LYS A CG  1 
ATOM   8973 C CD  . LYS C 2 558 ? 230.202 205.375 233.833 1.00 72.73  ? 558  LYS A CD  1 
ATOM   8974 C CE  . LYS C 2 558 ? 230.827 204.286 234.690 1.00 72.73  ? 558  LYS A CE  1 
ATOM   8975 N NZ  . LYS C 2 558 ? 232.310 204.259 234.559 1.00 72.73  ? 558  LYS A NZ  1 
ATOM   8976 N N   . PHE C 2 559 ? 227.953 202.655 229.316 1.00 66.51  ? 559  PHE A N   1 
ATOM   8977 C CA  . PHE C 2 559 ? 227.692 201.475 228.510 1.00 66.51  ? 559  PHE A CA  1 
ATOM   8978 C C   . PHE C 2 559 ? 229.001 200.870 228.010 1.00 66.51  ? 559  PHE A C   1 
ATOM   8979 O O   . PHE C 2 559 ? 230.079 201.460 228.121 1.00 66.51  ? 559  PHE A O   1 
ATOM   8980 C CB  . PHE C 2 559 ? 226.791 201.816 227.323 1.00 66.51  ? 559  PHE A CB  1 
ATOM   8981 C CG  . PHE C 2 559 ? 225.353 202.046 227.691 1.00 66.51  ? 559  PHE A CG  1 
ATOM   8982 C CD1 . PHE C 2 559 ? 224.898 201.789 228.972 1.00 66.51  ? 559  PHE A CD1 1 
ATOM   8983 C CD2 . PHE C 2 559 ? 224.453 202.508 226.746 1.00 66.51  ? 559  PHE A CD2 1 
ATOM   8984 C CE1 . PHE C 2 559 ? 223.575 202.000 229.306 1.00 66.51  ? 559  PHE A CE1 1 
ATOM   8985 C CE2 . PHE C 2 559 ? 223.129 202.718 227.074 1.00 66.51  ? 559  PHE A CE2 1 
ATOM   8986 C CZ  . PHE C 2 559 ? 222.689 202.463 228.356 1.00 66.51  ? 559  PHE A CZ  1 
ATOM   8987 N N   . LEU C 2 560 ? 228.895 199.670 227.454 1.00 62.97  ? 560  LEU A N   1 
ATOM   8988 C CA  . LEU C 2 560 ? 230.028 199.030 226.814 1.00 62.97  ? 560  LEU A CA  1 
ATOM   8989 C C   . LEU C 2 560 ? 230.295 199.677 225.458 1.00 62.97  ? 560  LEU A C   1 
ATOM   8990 O O   . LEU C 2 560 ? 229.395 200.266 224.854 1.00 62.97  ? 560  LEU A O   1 
ATOM   8991 C CB  . LEU C 2 560 ? 229.765 197.536 226.657 1.00 62.97  ? 560  LEU A CB  1 
ATOM   8992 C CG  . LEU C 2 560 ? 229.623 196.763 227.971 1.00 62.97  ? 560  LEU A CG  1 
ATOM   8993 C CD1 . LEU C 2 560 ? 229.424 195.279 227.712 1.00 62.97  ? 560  LEU A CD1 1 
ATOM   8994 C CD2 . LEU C 2 560 ? 230.833 196.996 228.861 1.00 62.97  ? 560  LEU A CD2 1 
ATOM   8995 N N   . PRO C 2 561 ? 231.534 199.592 224.960 1.00 61.81  ? 561  PRO A N   1 
ATOM   8996 C CA  . PRO C 2 561 ? 231.868 200.268 223.694 1.00 61.81  ? 561  PRO A CA  1 
ATOM   8997 C C   . PRO C 2 561 ? 231.059 199.797 222.493 1.00 61.81  ? 561  PRO A C   1 
ATOM   8998 O O   . PRO C 2 561 ? 231.154 200.424 221.430 1.00 61.81  ? 561  PRO A O   1 
ATOM   8999 C CB  . PRO C 2 561 ? 233.358 199.952 223.511 1.00 61.81  ? 561  PRO A CB  1 
ATOM   9000 C CG  . PRO C 2 561 ? 233.858 199.701 224.891 1.00 61.81  ? 561  PRO A CG  1 
ATOM   9001 C CD  . PRO C 2 561 ? 232.728 199.027 225.612 1.00 61.81  ? 561  PRO A CD  1 
ATOM   9002 N N   . PHE C 2 562 ? 230.271 198.727 222.618 1.00 60.21  ? 562  PHE A N   1 
ATOM   9003 C CA  . PHE C 2 562 ? 229.463 198.233 221.513 1.00 60.21  ? 562  PHE A CA  1 
ATOM   9004 C C   . PHE C 2 562 ? 227.964 198.295 221.762 1.00 60.21  ? 562  PHE A C   1 
ATOM   9005 O O   . PHE C 2 562 ? 227.199 198.274 220.792 1.00 60.21  ? 562  PHE A O   1 
ATOM   9006 C CB  . PHE C 2 562 ? 229.844 196.783 221.171 1.00 60.21  ? 562  PHE A CB  1 
ATOM   9007 C CG  . PHE C 2 562 ? 229.636 195.815 222.302 1.00 60.21  ? 562  PHE A CG  1 
ATOM   9008 C CD1 . PHE C 2 562 ? 230.632 195.602 223.241 1.00 60.21  ? 562  PHE A CD1 1 
ATOM   9009 C CD2 . PHE C 2 562 ? 228.448 195.112 222.422 1.00 60.21  ? 562  PHE A CD2 1 
ATOM   9010 C CE1 . PHE C 2 562 ? 230.445 194.711 224.280 1.00 60.21  ? 562  PHE A CE1 1 
ATOM   9011 C CE2 . PHE C 2 562 ? 228.256 194.220 223.459 1.00 60.21  ? 562  PHE A CE2 1 
ATOM   9012 C CZ  . PHE C 2 562 ? 229.255 194.020 224.388 1.00 60.21  ? 562  PHE A CZ  1 
ATOM   9013 N N   . GLN C 2 563 ? 227.524 198.370 223.015 1.00 62.32  ? 563  GLN A N   1 
ATOM   9014 C CA  . GLN C 2 563 ? 226.098 198.382 223.317 1.00 62.32  ? 563  GLN A CA  1 
ATOM   9015 C C   . GLN C 2 563 ? 225.493 199.728 222.938 1.00 62.32  ? 563  GLN A C   1 
ATOM   9016 O O   . GLN C 2 563 ? 225.938 200.776 223.418 1.00 62.32  ? 563  GLN A O   1 
ATOM   9017 C CB  . GLN C 2 563 ? 225.873 198.085 224.797 1.00 62.32  ? 563  GLN A CB  1 
ATOM   9018 C CG  . GLN C 2 563 ? 226.276 196.678 225.206 1.00 62.32  ? 563  GLN A CG  1 
ATOM   9019 C CD  . GLN C 2 563 ? 226.193 196.460 226.702 1.00 62.32  ? 563  GLN A CD  1 
ATOM   9020 O OE1 . GLN C 2 563 ? 226.251 197.409 227.482 1.00 62.32  ? 563  GLN A OE1 1 
ATOM   9021 N NE2 . GLN C 2 563 ? 226.054 195.205 227.111 1.00 62.32  ? 563  GLN A NE2 1 
ATOM   9022 N N   . GLN C 2 564 ? 224.476 199.699 222.076 1.00 65.70  ? 564  GLN A N   1 
ATOM   9023 C CA  . GLN C 2 564 ? 223.833 200.930 221.628 1.00 65.70  ? 564  GLN A CA  1 
ATOM   9024 C C   . GLN C 2 564 ? 222.847 201.452 222.667 1.00 65.70  ? 564  GLN A C   1 
ATOM   9025 O O   . GLN C 2 564 ? 222.994 202.568 223.175 1.00 65.70  ? 564  GLN A O   1 
ATOM   9026 C CB  . GLN C 2 564 ? 223.130 200.697 220.288 1.00 65.70  ? 564  GLN A CB  1 
ATOM   9027 C CG  . GLN C 2 564 ? 224.071 200.399 219.132 1.00 65.70  ? 564  GLN A CG  1 
ATOM   9028 C CD  . GLN C 2 564 ? 224.885 201.608 218.713 1.00 65.70  ? 564  GLN A CD  1 
ATOM   9029 O OE1 . GLN C 2 564 ? 224.538 202.745 219.031 1.00 65.70  ? 564  GLN A OE1 1 
ATOM   9030 N NE2 . GLN C 2 564 ? 225.975 201.366 217.995 1.00 65.70  ? 564  GLN A NE2 1 
ATOM   9031 N N   . PHE C 2 565 ? 221.832 200.657 222.995 1.00 67.10  ? 565  PHE A N   1 
ATOM   9032 C CA  . PHE C 2 565 ? 220.796 201.061 223.932 1.00 67.10  ? 565  PHE A CA  1 
ATOM   9033 C C   . PHE C 2 565 ? 220.655 200.012 225.025 1.00 67.10  ? 565  PHE A C   1 
ATOM   9034 O O   . PHE C 2 565 ? 221.240 198.928 224.961 1.00 67.10  ? 565  PHE A O   1 
ATOM   9035 C CB  . PHE C 2 565 ? 219.452 201.278 223.220 1.00 67.10  ? 565  PHE A CB  1 
ATOM   9036 C CG  . PHE C 2 565 ? 218.940 200.062 222.499 1.00 67.10  ? 565  PHE A CG  1 
ATOM   9037 C CD1 . PHE C 2 565 ? 218.061 199.191 223.120 1.00 67.10  ? 565  PHE A CD1 1 
ATOM   9038 C CD2 . PHE C 2 565 ? 219.334 199.794 221.199 1.00 67.10  ? 565  PHE A CD2 1 
ATOM   9039 C CE1 . PHE C 2 565 ? 217.588 198.073 222.459 1.00 67.10  ? 565  PHE A CE1 1 
ATOM   9040 C CE2 . PHE C 2 565 ? 218.865 198.679 220.533 1.00 67.10  ? 565  PHE A CE2 1 
ATOM   9041 C CZ  . PHE C 2 565 ? 217.990 197.818 221.164 1.00 67.10  ? 565  PHE A CZ  1 
ATOM   9042 N N   . GLY C 2 566 ? 219.867 200.354 226.045 1.00 70.30  ? 566  GLY A N   1 
ATOM   9043 C CA  . GLY C 2 566 ? 219.599 199.454 227.147 1.00 70.30  ? 566  GLY A CA  1 
ATOM   9044 C C   . GLY C 2 566 ? 218.133 199.494 227.529 1.00 70.30  ? 566  GLY A C   1 
ATOM   9045 O O   . GLY C 2 566 ? 217.328 200.184 226.902 1.00 70.30  ? 566  GLY A O   1 
ATOM   9046 N N   . ARG C 2 567 ? 217.802 198.742 228.575 1.00 72.36  ? 567  ARG A N   1 
ATOM   9047 C CA  . ARG C 2 567 ? 216.428 198.685 229.053 1.00 72.36  ? 567  ARG A CA  1 
ATOM   9048 C C   . ARG C 2 567 ? 216.427 198.274 230.517 1.00 72.36  ? 567  ARG A C   1 
ATOM   9049 O O   . ARG C 2 567 ? 217.371 197.651 231.010 1.00 72.36  ? 567  ARG A O   1 
ATOM   9050 C CB  . ARG C 2 567 ? 215.581 197.720 228.217 1.00 72.36  ? 567  ARG A CB  1 
ATOM   9051 C CG  . ARG C 2 567 ? 216.082 196.290 228.207 1.00 72.36  ? 567  ARG A CG  1 
ATOM   9052 C CD  . ARG C 2 567 ? 215.255 195.437 227.262 1.00 72.36  ? 567  ARG A CD  1 
ATOM   9053 N NE  . ARG C 2 567 ? 215.221 196.001 225.915 1.00 72.36  ? 567  ARG A NE  1 
ATOM   9054 C CZ  . ARG C 2 567 ? 214.523 195.488 224.908 1.00 72.36  ? 567  ARG A CZ  1 
ATOM   9055 N NH1 . ARG C 2 567 ? 214.552 196.069 223.716 1.00 72.36  ? 567  ARG A NH1 1 
ATOM   9056 N NH2 . ARG C 2 567 ? 213.796 194.395 225.090 1.00 72.36  ? 567  ARG A NH2 1 
ATOM   9057 N N   . ASP C 2 568 ? 215.346 198.635 231.204 1.00 82.47  ? 568  ASP A N   1 
ATOM   9058 C CA  . ASP C 2 568 ? 215.206 198.364 232.625 1.00 82.47  ? 568  ASP A CA  1 
ATOM   9059 C C   . ASP C 2 568 ? 214.760 196.918 232.843 1.00 82.47  ? 568  ASP A C   1 
ATOM   9060 O O   . ASP C 2 568 ? 214.604 196.135 231.901 1.00 82.47  ? 568  ASP A O   1 
ATOM   9061 C CB  . ASP C 2 568 ? 214.226 199.353 233.252 1.00 82.47  ? 568  ASP A CB  1 
ATOM   9062 C CG  . ASP C 2 568 ? 214.420 199.502 234.750 1.00 82.47  ? 568  ASP A CG  1 
ATOM   9063 O OD1 . ASP C 2 568 ? 215.447 200.080 235.163 1.00 82.47  ? 568  ASP A OD1 1 
ATOM   9064 O OD2 . ASP C 2 568 ? 213.546 199.040 235.512 1.00 82.47  ? 568  ASP A OD2 1 
ATOM   9065 N N   . ILE C 2 569 ? 214.556 196.556 234.112 1.00 82.05  ? 569  ILE A N   1 
ATOM   9066 C CA  . ILE C 2 569 ? 214.121 195.203 234.443 1.00 82.05  ? 569  ILE A CA  1 
ATOM   9067 C C   . ILE C 2 569 ? 212.719 194.939 233.908 1.00 82.05  ? 569  ILE A C   1 
ATOM   9068 O O   . ILE C 2 569 ? 212.376 193.796 233.579 1.00 82.05  ? 569  ILE A O   1 
ATOM   9069 C CB  . ILE C 2 569 ? 214.197 194.981 235.965 1.00 82.05  ? 569  ILE A CB  1 
ATOM   9070 C CG1 . ILE C 2 569 ? 215.552 195.441 236.504 1.00 82.05  ? 569  ILE A CG1 1 
ATOM   9071 C CG2 . ILE C 2 569 ? 213.965 193.517 236.308 1.00 82.05  ? 569  ILE A CG2 1 
ATOM   9072 C CD1 . ILE C 2 569 ? 216.730 194.696 235.916 1.00 82.05  ? 569  ILE A CD1 1 
ATOM   9073 N N   . ALA C 2 570 ? 211.894 195.978 233.797 1.00 84.00  ? 570  ALA A N   1 
ATOM   9074 C CA  . ALA C 2 570 ? 210.528 195.844 233.307 1.00 84.00  ? 570  ALA A CA  1 
ATOM   9075 C C   . ALA C 2 570 ? 210.447 195.720 231.789 1.00 84.00  ? 570  ALA A C   1 
ATOM   9076 O O   . ALA C 2 570 ? 209.348 195.841 231.236 1.00 84.00  ? 570  ALA A O   1 
ATOM   9077 C CB  . ALA C 2 570 ? 209.684 197.033 233.774 1.00 84.00  ? 570  ALA A CB  1 
ATOM   9078 N N   . ASP C 2 571 ? 211.575 195.486 231.116 1.00 83.11  ? 571  ASP A N   1 
ATOM   9079 C CA  . ASP C 2 571 ? 211.624 195.336 229.660 1.00 83.11  ? 571  ASP A CA  1 
ATOM   9080 C C   . ASP C 2 571 ? 211.060 196.574 228.963 1.00 83.11  ? 571  ASP A C   1 
ATOM   9081 O O   . ASP C 2 571 ? 210.200 196.489 228.083 1.00 83.11  ? 571  ASP A O   1 
ATOM   9082 C CB  . ASP C 2 571 ? 210.896 194.065 229.212 1.00 83.11  ? 571  ASP A CB  1 
ATOM   9083 C CG  . ASP C 2 571 ? 211.201 193.694 227.774 1.00 83.11  ? 571  ASP A CG  1 
ATOM   9084 O OD1 . ASP C 2 571 ? 212.351 193.299 227.492 1.00 83.11  ? 571  ASP A OD1 1 
ATOM   9085 O OD2 . ASP C 2 571 ? 210.290 193.796 226.925 1.00 83.11  ? 571  ASP A OD2 1 
ATOM   9086 N N   . THR C 2 572 ? 211.552 197.740 229.374 1.00 80.15  ? 572  THR A N   1 
ATOM   9087 C CA  . THR C 2 572 ? 211.172 199.014 228.781 1.00 80.15  ? 572  THR A CA  1 
ATOM   9088 C C   . THR C 2 572 ? 212.428 199.820 228.494 1.00 80.15  ? 572  THR A C   1 
ATOM   9089 O O   . THR C 2 572 ? 213.382 199.795 229.278 1.00 80.15  ? 572  THR A O   1 
ATOM   9090 C CB  . THR C 2 572 ? 210.238 199.814 229.700 1.00 80.15  ? 572  THR A CB  1 
ATOM   9091 O OG1 . THR C 2 572 ? 210.855 199.982 230.983 1.00 80.15  ? 572  THR A OG1 1 
ATOM   9092 C CG2 . THR C 2 572 ? 208.906 199.097 229.870 1.00 80.15  ? 572  THR A CG2 1 
ATOM   9093 N N   . THR C 2 573 ? 212.422 200.534 227.371 1.00 74.95  ? 573  THR A N   1 
ATOM   9094 C CA  . THR C 2 573 ? 213.586 201.310 226.961 1.00 74.95  ? 573  THR A CA  1 
ATOM   9095 C C   . THR C 2 573 ? 213.916 202.368 228.006 1.00 74.95  ? 573  THR A C   1 
ATOM   9096 O O   . THR C 2 573 ? 213.098 203.249 228.291 1.00 74.95  ? 573  THR A O   1 
ATOM   9097 C CB  . THR C 2 573 ? 213.332 201.961 225.603 1.00 74.95  ? 573  THR A CB  1 
ATOM   9098 O OG1 . THR C 2 573 ? 213.043 200.948 224.632 1.00 74.95  ? 573  THR A OG1 1 
ATOM   9099 C CG2 . THR C 2 573 ? 214.553 202.747 225.158 1.00 74.95  ? 573  THR A CG2 1 
ATOM   9100 N N   . ASP C 2 574 ? 215.115 202.279 228.574 1.00 76.13  ? 574  ASP A N   1 
ATOM   9101 C CA  . ASP C 2 574 ? 215.557 203.176 229.636 1.00 76.13  ? 574  ASP A CA  1 
ATOM   9102 C C   . ASP C 2 574 ? 216.622 204.163 229.188 1.00 76.13  ? 574  ASP A C   1 
ATOM   9103 O O   . ASP C 2 574 ? 216.552 205.340 229.547 1.00 76.13  ? 574  ASP A O   1 
ATOM   9104 C CB  . ASP C 2 574 ? 216.090 202.362 230.821 1.00 76.13  ? 574  ASP A CB  1 
ATOM   9105 C CG  . ASP C 2 574 ? 216.013 203.118 232.136 1.00 76.13  ? 574  ASP A CG  1 
ATOM   9106 O OD1 . ASP C 2 574 ? 216.034 204.366 232.118 1.00 76.13  ? 574  ASP A OD1 1 
ATOM   9107 O OD2 . ASP C 2 574 ? 215.930 202.459 233.193 1.00 76.13  ? 574  ASP A OD2 1 
ATOM   9108 N N   . ALA C 2 575 ? 217.607 203.720 228.410 1.00 71.05  ? 575  ALA A N   1 
ATOM   9109 C CA  . ALA C 2 575 ? 218.682 204.599 227.978 1.00 71.05  ? 575  ALA A CA  1 
ATOM   9110 C C   . ALA C 2 575 ? 219.128 204.202 226.579 1.00 71.05  ? 575  ALA A C   1 
ATOM   9111 O O   . ALA C 2 575 ? 218.838 203.104 226.099 1.00 71.05  ? 575  ALA A O   1 
ATOM   9112 C CB  . ALA C 2 575 ? 219.866 204.559 228.951 1.00 71.05  ? 575  ALA A CB  1 
ATOM   9113 N N   . VAL C 2 576 ? 219.843 205.118 225.931 1.00 68.01  ? 576  VAL A N   1 
ATOM   9114 C CA  . VAL C 2 576 ? 220.348 204.904 224.579 1.00 68.01  ? 576  VAL A CA  1 
ATOM   9115 C C   . VAL C 2 576 ? 221.570 205.791 224.380 1.00 68.01  ? 576  VAL A C   1 
ATOM   9116 O O   . VAL C 2 576 ? 221.608 206.933 224.849 1.00 68.01  ? 576  VAL A O   1 
ATOM   9117 C CB  . VAL C 2 576 ? 219.257 205.185 223.521 1.00 68.01  ? 576  VAL A CB  1 
ATOM   9118 C CG1 . VAL C 2 576 ? 218.717 206.600 223.665 1.00 68.01  ? 576  VAL A CG1 1 
ATOM   9119 C CG2 . VAL C 2 576 ? 219.790 204.945 222.115 1.00 68.01  ? 576  VAL A CG2 1 
ATOM   9120 N N   . ARG C 2 577 ? 222.577 205.254 223.697 1.00 65.81  ? 577  ARG A N   1 
ATOM   9121 C CA  . ARG C 2 577 ? 223.799 205.992 223.411 1.00 65.81  ? 577  ARG A CA  1 
ATOM   9122 C C   . ARG C 2 577 ? 223.614 206.827 222.151 1.00 65.81  ? 577  ARG A C   1 
ATOM   9123 O O   . ARG C 2 577 ? 223.146 206.321 221.126 1.00 65.81  ? 577  ARG A O   1 
ATOM   9124 C CB  . ARG C 2 577 ? 224.983 205.038 223.246 1.00 65.81  ? 577  ARG A CB  1 
ATOM   9125 C CG  . ARG C 2 577 ? 226.249 205.701 222.735 1.00 65.81  ? 577  ARG A CG  1 
ATOM   9126 C CD  . ARG C 2 577 ? 227.395 204.709 222.631 1.00 65.81  ? 577  ARG A CD  1 
ATOM   9127 N NE  . ARG C 2 577 ? 227.835 204.239 223.941 1.00 65.81  ? 577  ARG A NE  1 
ATOM   9128 C CZ  . ARG C 2 577 ? 228.865 203.422 224.133 1.00 65.81  ? 577  ARG A CZ  1 
ATOM   9129 N NH1 . ARG C 2 577 ? 229.197 203.047 225.360 1.00 65.81  ? 577  ARG A NH1 1 
ATOM   9130 N NH2 . ARG C 2 577 ? 229.565 202.979 223.098 1.00 65.81  ? 577  ARG A NH2 1 
ATOM   9131 N N   . ASP C 2 578 ? 223.976 208.101 222.234 1.00 69.01  ? 578  ASP A N   1 
ATOM   9132 C CA  . ASP C 2 578 ? 223.874 208.982 221.078 1.00 69.01  ? 578  ASP A CA  1 
ATOM   9133 C C   . ASP C 2 578 ? 224.872 208.546 220.011 1.00 69.01  ? 578  ASP A C   1 
ATOM   9134 O O   . ASP C 2 578 ? 226.063 208.396 220.308 1.00 69.01  ? 578  ASP A O   1 
ATOM   9135 C CB  . ASP C 2 578 ? 224.128 210.431 221.484 1.00 69.01  ? 578  ASP A CB  1 
ATOM   9136 C CG  . ASP C 2 578 ? 223.993 211.394 220.322 1.00 69.01  ? 578  ASP A CG  1 
ATOM   9137 O OD1 . ASP C 2 578 ? 222.856 211.597 219.846 1.00 69.01  ? 578  ASP A OD1 1 
ATOM   9138 O OD2 . ASP C 2 578 ? 225.023 211.947 219.883 1.00 69.01  ? 578  ASP A OD2 1 
ATOM   9139 N N   . PRO C 2 579 ? 224.434 208.333 218.766 1.00 68.23  ? 579  PRO A N   1 
ATOM   9140 C CA  . PRO C 2 579 ? 225.350 207.831 217.731 1.00 68.23  ? 579  PRO A CA  1 
ATOM   9141 C C   . PRO C 2 579 ? 226.388 208.840 217.268 1.00 68.23  ? 579  PRO A C   1 
ATOM   9142 O O   . PRO C 2 579 ? 227.239 208.486 216.444 1.00 68.23  ? 579  PRO A O   1 
ATOM   9143 C CB  . PRO C 2 579 ? 224.401 207.455 216.586 1.00 68.23  ? 579  PRO A CB  1 
ATOM   9144 C CG  . PRO C 2 579 ? 223.223 208.345 216.775 1.00 68.23  ? 579  PRO A CG  1 
ATOM   9145 C CD  . PRO C 2 579 ? 223.062 208.504 218.260 1.00 68.23  ? 579  PRO A CD  1 
ATOM   9146 N N   . GLN C 2 580 ? 226.355 210.077 217.759 1.00 70.17  ? 580  GLN A N   1 
ATOM   9147 C CA  . GLN C 2 580 ? 227.329 211.095 217.382 1.00 70.17  ? 580  GLN A CA  1 
ATOM   9148 C C   . GLN C 2 580 ? 228.268 211.481 218.512 1.00 70.17  ? 580  GLN A C   1 
ATOM   9149 O O   . GLN C 2 580 ? 229.467 211.649 218.279 1.00 70.17  ? 580  GLN A O   1 
ATOM   9150 C CB  . GLN C 2 580 ? 226.614 212.351 216.873 1.00 70.17  ? 580  GLN A CB  1 
ATOM   9151 C CG  . GLN C 2 580 ? 225.801 212.133 215.610 1.00 70.17  ? 580  GLN A CG  1 
ATOM   9152 C CD  . GLN C 2 580 ? 225.218 213.420 215.062 1.00 70.17  ? 580  GLN A CD  1 
ATOM   9153 O OE1 . GLN C 2 580 ? 224.469 213.409 214.087 1.00 70.17  ? 580  GLN A OE1 1 
ATOM   9154 N NE2 . GLN C 2 580 ? 225.564 214.539 215.687 1.00 70.17  ? 580  GLN A NE2 1 
ATOM   9155 N N   . THR C 2 581 ? 227.757 211.625 219.734 1.00 67.68  ? 581  THR A N   1 
ATOM   9156 C CA  . THR C 2 581 ? 228.572 212.014 220.875 1.00 67.68  ? 581  THR A CA  1 
ATOM   9157 C C   . THR C 2 581 ? 228.970 210.834 221.753 1.00 67.68  ? 581  THR A C   1 
ATOM   9158 O O   . THR C 2 581 ? 229.788 211.009 222.663 1.00 67.68  ? 581  THR A O   1 
ATOM   9159 C CB  . THR C 2 581 ? 227.829 213.055 221.724 1.00 67.68  ? 581  THR A CB  1 
ATOM   9160 O OG1 . THR C 2 581 ? 226.992 213.851 220.877 1.00 67.68  ? 581  THR A OG1 1 
ATOM   9161 C CG2 . THR C 2 581 ? 228.815 213.971 222.436 1.00 67.68  ? 581  THR A CG2 1 
ATOM   9162 N N   . LEU C 2 582 ? 228.416 209.646 221.499 1.00 67.71  ? 582  LEU A N   1 
ATOM   9163 C CA  . LEU C 2 582 ? 228.707 208.441 222.279 1.00 67.71  ? 582  LEU A CA  1 
ATOM   9164 C C   . LEU C 2 582 ? 228.369 208.626 223.755 1.00 67.71  ? 582  LEU A C   1 
ATOM   9165 O O   . LEU C 2 582 ? 229.005 208.031 224.628 1.00 67.71  ? 582  LEU A O   1 
ATOM   9166 C CB  . LEU C 2 582 ? 230.166 207.999 222.119 1.00 67.71  ? 582  LEU A CB  1 
ATOM   9167 C CG  . LEU C 2 582 ? 230.631 207.510 220.744 1.00 67.71  ? 582  LEU A CG  1 
ATOM   9168 C CD1 . LEU C 2 582 ? 229.571 206.634 220.091 1.00 67.71  ? 582  LEU A CD1 1 
ATOM   9169 C CD2 . LEU C 2 582 ? 231.022 208.670 219.838 1.00 67.71  ? 582  LEU A CD2 1 
ATOM   9170 N N   . GLU C 2 583 ? 227.369 209.450 224.046 1.00 68.73  ? 583  GLU A N   1 
ATOM   9171 C CA  . GLU C 2 583 ? 226.933 209.698 225.410 1.00 68.73  ? 583  GLU A CA  1 
ATOM   9172 C C   . GLU C 2 583 ? 225.626 208.967 225.687 1.00 68.73  ? 583  GLU A C   1 
ATOM   9173 O O   . GLU C 2 583 ? 224.786 208.798 224.801 1.00 68.73  ? 583  GLU A O   1 
ATOM   9174 C CB  . GLU C 2 583 ? 226.760 211.197 225.668 1.00 68.73  ? 583  GLU A CB  1 
ATOM   9175 C CG  . GLU C 2 583 ? 225.760 211.878 224.749 1.00 68.73  ? 583  GLU A CG  1 
ATOM   9176 C CD  . GLU C 2 583 ? 225.569 213.344 225.083 1.00 68.73  ? 583  GLU A CD  1 
ATOM   9177 O OE1 . GLU C 2 583 ? 226.176 213.815 226.067 1.00 68.73  ? 583  GLU A OE1 1 
ATOM   9178 O OE2 . GLU C 2 583 ? 224.811 214.026 224.362 1.00 68.73  ? 583  GLU A OE2 1 
ATOM   9179 N N   . ILE C 2 584 ? 225.466 208.532 226.931 1.00 71.54  ? 584  ILE A N   1 
ATOM   9180 C CA  . ILE C 2 584 ? 224.271 207.816 227.359 1.00 71.54  ? 584  ILE A CA  1 
ATOM   9181 C C   . ILE C 2 584 ? 223.232 208.828 227.825 1.00 71.54  ? 584  ILE A C   1 
ATOM   9182 O O   . ILE C 2 584 ? 223.536 209.729 228.616 1.00 71.54  ? 584  ILE A O   1 
ATOM   9183 C CB  . ILE C 2 584 ? 224.604 206.807 228.471 1.00 71.54  ? 584  ILE A CB  1 
ATOM   9184 C CG1 . ILE C 2 584 ? 223.322 206.278 229.118 1.00 71.54  ? 584  ILE A CG1 1 
ATOM   9185 C CG2 . ILE C 2 584 ? 225.527 207.434 229.506 1.00 71.54  ? 584  ILE A CG2 1 
ATOM   9186 C CD1 . ILE C 2 584 ? 223.567 205.379 230.307 1.00 71.54  ? 584  ILE A CD1 1 
ATOM   9187 N N   . LEU C 2 585 ? 222.007 208.686 227.327 1.00 71.97  ? 585  LEU A N   1 
ATOM   9188 C CA  . LEU C 2 585 ? 220.907 209.579 227.663 1.00 71.97  ? 585  LEU A CA  1 
ATOM   9189 C C   . LEU C 2 585 ? 219.770 208.770 228.267 1.00 71.97  ? 585  LEU A C   1 
ATOM   9190 O O   . LEU C 2 585 ? 219.291 207.812 227.652 1.00 71.97  ? 585  LEU A O   1 
ATOM   9191 C CB  . LEU C 2 585 ? 220.420 210.340 226.427 1.00 71.97  ? 585  LEU A CB  1 
ATOM   9192 C CG  . LEU C 2 585 ? 221.469 211.172 225.687 1.00 71.97  ? 585  LEU A CG  1 
ATOM   9193 C CD1 . LEU C 2 585 ? 220.857 211.850 224.472 1.00 71.97  ? 585  LEU A CD1 1 
ATOM   9194 C CD2 . LEU C 2 585 ? 222.095 212.198 226.619 1.00 71.97  ? 585  LEU A CD2 1 
ATOM   9195 N N   . ASP C 2 586 ? 219.341 209.157 229.465 1.00 75.71  ? 586  ASP A N   1 
ATOM   9196 C CA  . ASP C 2 586 ? 218.231 208.479 230.116 1.00 75.71  ? 586  ASP A CA  1 
ATOM   9197 C C   . ASP C 2 586 ? 216.914 208.827 229.432 1.00 75.71  ? 586  ASP A C   1 
ATOM   9198 O O   . ASP C 2 586 ? 216.732 209.926 228.901 1.00 75.71  ? 586  ASP A O   1 
ATOM   9199 C CB  . ASP C 2 586 ? 218.164 208.853 231.596 1.00 75.71  ? 586  ASP A CB  1 
ATOM   9200 C CG  . ASP C 2 586 ? 219.306 208.265 232.398 1.00 75.71  ? 586  ASP A CG  1 
ATOM   9201 O OD1 . ASP C 2 586 ? 219.767 207.157 232.052 1.00 75.71  ? 586  ASP A OD1 1 
ATOM   9202 O OD2 . ASP C 2 586 ? 219.742 208.909 233.375 1.00 75.71  ? 586  ASP A OD2 1 
ATOM   9203 N N   . ILE C 2 587 ? 215.988 207.873 229.451 1.00 76.89  ? 587  ILE A N   1 
ATOM   9204 C CA  . ILE C 2 587 ? 214.674 208.028 228.839 1.00 76.89  ? 587  ILE A CA  1 
ATOM   9205 C C   . ILE C 2 587 ? 213.625 207.804 229.918 1.00 76.89  ? 587  ILE A C   1 
ATOM   9206 O O   . ILE C 2 587 ? 213.569 206.727 230.523 1.00 76.89  ? 587  ILE A O   1 
ATOM   9207 C CB  . ILE C 2 587 ? 214.470 207.058 227.666 1.00 76.89  ? 587  ILE A CB  1 
ATOM   9208 C CG1 . ILE C 2 587 ? 215.576 207.242 226.626 1.00 76.89  ? 587  ILE A CG1 1 
ATOM   9209 C CG2 . ILE C 2 587 ? 213.102 207.266 227.035 1.00 76.89  ? 587  ILE A CG2 1 
ATOM   9210 C CD1 . ILE C 2 587 ? 215.480 206.290 225.459 1.00 76.89  ? 587  ILE A CD1 1 
ATOM   9211 N N   . THR C 2 588 ? 212.799 208.819 230.156 1.00 84.34  ? 588  THR A N   1 
ATOM   9212 C CA  . THR C 2 588 ? 211.731 208.751 231.135 1.00 84.34  ? 588  THR A CA  1 
ATOM   9213 C C   . THR C 2 588 ? 210.401 209.044 230.455 1.00 84.34  ? 588  THR A C   1 
ATOM   9214 O O   . THR C 2 588 ? 210.284 210.053 229.745 1.00 84.34  ? 588  THR A O   1 
ATOM   9215 C CB  . THR C 2 588 ? 211.968 209.754 232.278 1.00 84.34  ? 588  THR A CB  1 
ATOM   9216 O OG1 . THR C 2 588 ? 213.200 209.445 232.941 1.00 84.34  ? 588  THR A OG1 1 
ATOM   9217 C CG2 . THR C 2 588 ? 210.828 209.700 233.285 1.00 84.34  ? 588  THR A CG2 1 
ATOM   9218 N N   . PRO C 2 589 ? 209.386 208.198 230.632 1.00 93.41  ? 589  PRO A N   1 
ATOM   9219 C CA  . PRO C 2 589 ? 208.088 208.463 229.997 1.00 93.41  ? 589  PRO A CA  1 
ATOM   9220 C C   . PRO C 2 589 ? 207.441 209.710 230.581 1.00 93.41  ? 589  PRO A C   1 
ATOM   9221 O O   . PRO C 2 589 ? 207.425 209.907 231.798 1.00 93.41  ? 589  PRO A O   1 
ATOM   9222 C CB  . PRO C 2 589 ? 207.274 207.202 230.309 1.00 93.41  ? 589  PRO A CB  1 
ATOM   9223 C CG  . PRO C 2 589 ? 207.915 206.635 231.534 1.00 93.41  ? 589  PRO A CG  1 
ATOM   9224 C CD  . PRO C 2 589 ? 209.379 206.945 231.407 1.00 93.41  ? 589  PRO A CD  1 
ATOM   9225 N N   . CYS C 2 590 ? 206.915 210.556 229.698 1.00 99.66  ? 590  CYS A N   1 
ATOM   9226 C CA  . CYS C 2 590 ? 206.279 211.797 230.121 1.00 99.66  ? 590  CYS A CA  1 
ATOM   9227 C C   . CYS C 2 590 ? 205.034 211.481 230.941 1.00 99.66  ? 590  CYS A C   1 
ATOM   9228 O O   . CYS C 2 590 ? 204.121 210.802 230.459 1.00 99.66  ? 590  CYS A O   1 
ATOM   9229 C CB  . CYS C 2 590 ? 205.932 212.648 228.902 1.00 99.66  ? 590  CYS A CB  1 
ATOM   9230 S SG  . CYS C 2 590 ? 207.241 212.677 227.648 1.00 99.66  ? 590  CYS A SG  1 
ATOM   9231 N N   . SER C 2 591 ? 205.002 211.966 232.179 1.00 100.91 ? 591  SER A N   1 
ATOM   9232 C CA  . SER C 2 591 ? 203.927 211.632 233.100 1.00 100.91 ? 591  SER A CA  1 
ATOM   9233 C C   . SER C 2 591 ? 202.590 212.175 232.601 1.00 100.91 ? 591  SER A C   1 
ATOM   9234 O O   . SER C 2 591 ? 202.523 213.112 231.800 1.00 100.91 ? 591  SER A O   1 
ATOM   9235 C CB  . SER C 2 591 ? 204.226 212.180 234.495 1.00 100.91 ? 591  SER A CB  1 
ATOM   9236 O OG  . SER C 2 591 ? 204.344 213.592 234.475 1.00 100.91 ? 591  SER A OG  1 
ATOM   9237 N N   . PHE C 2 592 ? 201.515 211.569 233.093 1.00 100.49 ? 592  PHE A N   1 
ATOM   9238 C CA  . PHE C 2 592 ? 200.166 211.950 232.695 1.00 100.49 ? 592  PHE A CA  1 
ATOM   9239 C C   . PHE C 2 592 ? 199.378 212.490 233.883 1.00 100.49 ? 592  PHE A C   1 
ATOM   9240 O O   . PHE C 2 592 ? 199.673 212.167 235.034 1.00 100.49 ? 592  PHE A O   1 
ATOM   9241 C CB  . PHE C 2 592 ? 199.435 210.758 232.075 1.00 100.49 ? 592  PHE A CB  1 
ATOM   9242 C CG  . PHE C 2 592 ? 200.118 210.192 230.862 1.00 100.49 ? 592  PHE A CG  1 
ATOM   9243 C CD1 . PHE C 2 592 ? 201.057 209.181 230.986 1.00 100.49 ? 592  PHE A CD1 1 
ATOM   9244 C CD2 . PHE C 2 592 ? 199.821 210.670 229.598 1.00 100.49 ? 592  PHE A CD2 1 
ATOM   9245 C CE1 . PHE C 2 592 ? 201.686 208.660 229.872 1.00 100.49 ? 592  PHE A CE1 1 
ATOM   9246 C CE2 . PHE C 2 592 ? 200.446 210.153 228.480 1.00 100.49 ? 592  PHE A CE2 1 
ATOM   9247 C CZ  . PHE C 2 592 ? 201.380 209.147 228.617 1.00 100.49 ? 592  PHE A CZ  1 
HETATM 9248 C C1  . NAG D 3 .   ? 213.831 203.985 153.330 1.00 77.78  ? 1    NAG B C1  1 
HETATM 9249 C C2  . NAG D 3 .   ? 212.382 203.851 153.791 1.00 77.78  ? 1    NAG B C2  1 
HETATM 9250 C C3  . NAG D 3 .   ? 212.116 204.786 154.968 1.00 77.78  ? 1    NAG B C3  1 
HETATM 9251 C C4  . NAG D 3 .   ? 213.135 204.556 156.077 1.00 77.78  ? 1    NAG B C4  1 
HETATM 9252 C C5  . NAG D 3 .   ? 214.555 204.638 155.520 1.00 77.78  ? 1    NAG B C5  1 
HETATM 9253 C C6  . NAG D 3 .   ? 215.612 204.281 156.539 1.00 77.78  ? 1    NAG B C6  1 
HETATM 9254 C C7  . NAG D 3 .   ? 210.337 203.427 152.503 1.00 77.78  ? 1    NAG B C7  1 
HETATM 9255 C C8  . NAG D 3 .   ? 209.502 203.846 151.330 1.00 77.78  ? 1    NAG B C8  1 
HETATM 9256 N N2  . NAG D 3 .   ? 211.460 204.125 152.702 1.00 77.78  ? 1    NAG B N2  1 
HETATM 9257 O O3  . NAG D 3 .   ? 210.799 204.564 155.457 1.00 77.78  ? 1    NAG B O3  1 
HETATM 9258 O O4  . NAG D 3 .   ? 212.984 205.546 157.088 1.00 77.78  ? 1    NAG B O4  1 
HETATM 9259 O O5  . NAG D 3 .   ? 214.710 203.722 154.427 1.00 77.78  ? 1    NAG B O5  1 
HETATM 9260 O O6  . NAG D 3 .   ? 216.819 204.993 156.307 1.00 77.78  ? 1    NAG B O6  1 
HETATM 9261 O O7  . NAG D 3 .   ? 210.010 202.500 153.236 1.00 77.78  ? 1    NAG B O7  1 
HETATM 9262 C C1  . NAG D 3 .   ? 212.349 204.968 158.245 1.00 93.65  ? 2    NAG B C1  1 
HETATM 9263 C C2  . NAG D 3 .   ? 213.018 205.526 159.501 1.00 93.65  ? 2    NAG B C2  1 
HETATM 9264 C C3  . NAG D 3 .   ? 212.330 204.984 160.750 1.00 93.65  ? 2    NAG B C3  1 
HETATM 9265 C C4  . NAG D 3 .   ? 210.832 205.251 160.691 1.00 93.65  ? 2    NAG B C4  1 
HETATM 9266 C C5  . NAG D 3 .   ? 210.251 204.707 159.390 1.00 93.65  ? 2    NAG B C5  1 
HETATM 9267 C C6  . NAG D 3 .   ? 208.789 205.045 159.208 1.00 93.65  ? 2    NAG B C6  1 
HETATM 9268 C C7  . NAG D 3 .   ? 215.395 206.135 159.642 1.00 93.65  ? 2    NAG B C7  1 
HETATM 9269 C C8  . NAG D 3 .   ? 214.928 207.555 159.758 1.00 93.65  ? 2    NAG B C8  1 
HETATM 9270 N N2  . NAG D 3 .   ? 214.437 205.209 159.521 1.00 93.65  ? 2    NAG B N2  1 
HETATM 9271 O O3  . NAG D 3 .   ? 212.890 205.601 161.904 1.00 93.65  ? 2    NAG B O3  1 
HETATM 9272 O O4  . NAG D 3 .   ? 210.183 204.627 161.793 1.00 93.65  ? 2    NAG B O4  1 
HETATM 9273 O O5  . NAG D 3 .   ? 210.948 205.271 158.269 1.00 93.65  ? 2    NAG B O5  1 
HETATM 9274 O O6  . NAG D 3 .   ? 208.623 206.312 158.587 1.00 93.65  ? 2    NAG B O6  1 
HETATM 9275 O O7  . NAG D 3 .   ? 216.586 205.839 159.656 1.00 93.65  ? 2    NAG B O7  1 
HETATM 9276 C C1  . NAG E 3 .   ? 204.134 241.400 166.225 1.00 77.23  ? 1    NAG E C1  1 
HETATM 9277 C C2  . NAG E 3 .   ? 203.771 242.845 165.883 1.00 77.23  ? 1    NAG E C2  1 
HETATM 9278 C C3  . NAG E 3 .   ? 204.629 243.817 166.690 1.00 77.23  ? 1    NAG E C3  1 
HETATM 9279 C C4  . NAG E 3 .   ? 204.534 243.500 168.177 1.00 77.23  ? 1    NAG E C4  1 
HETATM 9280 C C5  . NAG E 3 .   ? 204.865 242.031 168.427 1.00 77.23  ? 1    NAG E C5  1 
HETATM 9281 C C6  . NAG E 3 .   ? 204.669 241.616 169.866 1.00 77.23  ? 1    NAG E C6  1 
HETATM 9282 C C7  . NAG E 3 .   ? 205.029 243.008 163.757 1.00 77.23  ? 1    NAG E C7  1 
HETATM 9283 C C8  . NAG E 3 .   ? 204.928 243.323 162.295 1.00 77.23  ? 1    NAG E C8  1 
HETATM 9284 N N2  . NAG E 3 .   ? 203.890 243.108 164.455 1.00 77.23  ? 1    NAG E N2  1 
HETATM 9285 O O3  . NAG E 3 .   ? 204.193 245.149 166.446 1.00 77.23  ? 1    NAG E O3  1 
HETATM 9286 O O4  . NAG E 3 .   ? 205.442 244.317 168.907 1.00 77.23  ? 1    NAG E O4  1 
HETATM 9287 O O5  . NAG E 3 .   ? 204.008 241.193 167.637 1.00 77.23  ? 1    NAG E O5  1 
HETATM 9288 O O6  . NAG E 3 .   ? 203.297 241.654 170.234 1.00 77.23  ? 1    NAG E O6  1 
HETATM 9289 O O7  . NAG E 3 .   ? 206.093 242.680 164.277 1.00 77.23  ? 1    NAG E O7  1 
HETATM 9290 C C1  . NAG E 3 .   ? 204.695 245.248 169.715 1.00 86.07  ? 2    NAG E C1  1 
HETATM 9291 C C2  . NAG E 3 .   ? 205.660 245.928 170.686 1.00 86.07  ? 2    NAG E C2  1 
HETATM 9292 C C3  . NAG E 3 .   ? 204.919 246.962 171.529 1.00 86.07  ? 2    NAG E C3  1 
HETATM 9293 C C4  . NAG E 3 .   ? 204.167 247.938 170.635 1.00 86.07  ? 2    NAG E C4  1 
HETATM 9294 C C5  . NAG E 3 .   ? 203.266 247.180 169.665 1.00 86.07  ? 2    NAG E C5  1 
HETATM 9295 C C6  . NAG E 3 .   ? 202.580 248.082 168.666 1.00 86.07  ? 2    NAG E C6  1 
HETATM 9296 C C7  . NAG E 3 .   ? 207.586 245.068 171.942 1.00 86.07  ? 2    NAG E C7  1 
HETATM 9297 C C8  . NAG E 3 .   ? 208.102 243.966 172.817 1.00 86.07  ? 2    NAG E C8  1 
HETATM 9298 N N2  . NAG E 3 .   ? 206.317 244.950 171.538 1.00 86.07  ? 2    NAG E N2  1 
HETATM 9299 O O3  . NAG E 3 .   ? 205.851 247.666 172.342 1.00 86.07  ? 2    NAG E O3  1 
HETATM 9300 O O4  . NAG E 3 .   ? 203.372 248.812 171.428 1.00 86.07  ? 2    NAG E O4  1 
HETATM 9301 O O5  . NAG E 3 .   ? 204.044 246.240 168.908 1.00 86.07  ? 2    NAG E O5  1 
HETATM 9302 O O6  . NAG E 3 .   ? 203.402 249.187 168.315 1.00 86.07  ? 2    NAG E O6  1 
HETATM 9303 O O7  . NAG E 3 .   ? 208.285 246.022 171.616 1.00 86.07  ? 2    NAG E O7  1 
HETATM 9304 C C1  . NAG F 3 .   ? 248.159 169.047 195.270 1.00 101.72 ? 1    NAG F C1  1 
HETATM 9305 C C2  . NAG F 3 .   ? 248.427 169.373 193.795 1.00 101.72 ? 1    NAG F C2  1 
HETATM 9306 C C3  . NAG F 3 .   ? 247.165 169.158 192.964 1.00 101.72 ? 1    NAG F C3  1 
HETATM 9307 C C4  . NAG F 3 .   ? 246.624 167.752 193.179 1.00 101.72 ? 1    NAG F C4  1 
HETATM 9308 C C5  . NAG F 3 .   ? 246.391 167.509 194.666 1.00 101.72 ? 1    NAG F C5  1 
HETATM 9309 C C6  . NAG F 3 .   ? 245.941 166.100 194.973 1.00 101.72 ? 1    NAG F C6  1 
HETATM 9310 C C7  . NAG F 3 .   ? 249.926 171.060 192.830 1.00 101.72 ? 1    NAG F C7  1 
HETATM 9311 C C8  . NAG F 3 .   ? 250.297 172.511 192.793 1.00 101.72 ? 1    NAG F C8  1 
HETATM 9312 N N2  . NAG F 3 .   ? 248.915 170.734 193.640 1.00 101.72 ? 1    NAG F N2  1 
HETATM 9313 O O3  . NAG F 3 .   ? 247.465 169.361 191.588 1.00 101.72 ? 1    NAG F O3  1 
HETATM 9314 O O4  . NAG F 3 .   ? 245.419 167.543 192.449 1.00 101.72 ? 1    NAG F O4  1 
HETATM 9315 O O5  . NAG F 3 .   ? 247.618 167.716 195.383 1.00 101.72 ? 1    NAG F O5  1 
HETATM 9316 O O6  . NAG F 3 .   ? 247.036 165.274 195.343 1.00 101.72 ? 1    NAG F O6  1 
HETATM 9317 O O7  . NAG F 3 .   ? 250.516 170.220 192.156 1.00 101.72 ? 1    NAG F O7  1 
HETATM 9318 C C1  . NAG F 3 .   ? 244.442 168.573 192.699 1.00 106.90 ? 2    NAG F C1  1 
HETATM 9319 C C2  . NAG F 3 .   ? 243.816 168.965 191.362 1.00 106.90 ? 2    NAG F C2  1 
HETATM 9320 C C3  . NAG F 3 .   ? 242.735 170.021 191.575 1.00 106.90 ? 2    NAG F C3  1 
HETATM 9321 C C4  . NAG F 3 .   ? 241.718 169.541 192.602 1.00 106.90 ? 2    NAG F C4  1 
HETATM 9322 C C5  . NAG F 3 .   ? 242.425 169.121 193.887 1.00 106.90 ? 2    NAG F C5  1 
HETATM 9323 C C6  . NAG F 3 .   ? 241.488 168.516 194.907 1.00 106.90 ? 2    NAG F C6  1 
HETATM 9324 C C7  . NAG F 3 .   ? 245.142 168.807 189.303 1.00 106.90 ? 2    NAG F C7  1 
HETATM 9325 C C8  . NAG F 3 .   ? 246.206 169.445 188.463 1.00 106.90 ? 2    NAG F C8  1 
HETATM 9326 N N2  . NAG F 3 .   ? 244.826 169.447 190.434 1.00 106.90 ? 2    NAG F N2  1 
HETATM 9327 O O3  . NAG F 3 .   ? 242.086 170.289 190.337 1.00 106.90 ? 2    NAG F O3  1 
HETATM 9328 O O4  . NAG F 3 .   ? 240.793 170.581 192.893 1.00 106.90 ? 2    NAG F O4  1 
HETATM 9329 O O5  . NAG F 3 .   ? 243.418 168.126 193.597 1.00 106.90 ? 2    NAG F O5  1 
HETATM 9330 O O6  . NAG F 3 .   ? 241.674 167.111 195.014 1.00 106.90 ? 2    NAG F O6  1 
HETATM 9331 O O7  . NAG F 3 .   ? 244.593 167.760 188.974 1.00 106.90 ? 2    NAG F O7  1 
HETATM 9332 C C1  . NAG G 3 .   ? 249.209 192.897 202.781 1.00 83.41  ? 1    NAG G C1  1 
HETATM 9333 C C2  . NAG G 3 .   ? 250.388 193.476 202.004 1.00 83.41  ? 1    NAG G C2  1 
HETATM 9334 C C3  . NAG G 3 .   ? 250.071 194.896 201.546 1.00 83.41  ? 1    NAG G C3  1 
HETATM 9335 C C4  . NAG G 3 .   ? 248.762 194.923 200.768 1.00 83.41  ? 1    NAG G C4  1 
HETATM 9336 C C5  . NAG G 3 .   ? 247.646 194.273 201.583 1.00 83.41  ? 1    NAG G C5  1 
HETATM 9337 C C6  . NAG G 3 .   ? 246.350 194.144 200.817 1.00 83.41  ? 1    NAG G C6  1 
HETATM 9338 C C7  . NAG G 3 .   ? 252.509 192.475 202.727 1.00 83.41  ? 1    NAG G C7  1 
HETATM 9339 C C8  . NAG G 3 .   ? 253.702 192.613 203.624 1.00 83.41  ? 1    NAG G C8  1 
HETATM 9340 N N2  . NAG G 3 .   ? 251.602 193.454 202.804 1.00 83.41  ? 1    NAG G N2  1 
HETATM 9341 O O3  . NAG G 3 .   ? 251.132 195.379 200.731 1.00 83.41  ? 1    NAG G O3  1 
HETATM 9342 O O4  . NAG G 3 .   ? 248.404 196.269 200.474 1.00 83.41  ? 1    NAG G O4  1 
HETATM 9343 O O5  . NAG G 3 .   ? 248.030 192.945 201.970 1.00 83.41  ? 1    NAG G O5  1 
HETATM 9344 O O6  . NAG G 3 .   ? 246.348 192.984 199.995 1.00 83.41  ? 1    NAG G O6  1 
HETATM 9345 O O7  . NAG G 3 .   ? 252.372 191.521 201.968 1.00 83.41  ? 1    NAG G O7  1 
HETATM 9346 C C1  . NAG G 3 .   ? 248.468 196.484 199.049 1.00 92.80  ? 2    NAG G C1  1 
HETATM 9347 C C2  . NAG G 3 .   ? 248.350 197.985 198.782 1.00 92.80  ? 2    NAG G C2  1 
HETATM 9348 C C3  . NAG G 3 .   ? 248.459 198.264 197.286 1.00 92.80  ? 2    NAG G C3  1 
HETATM 9349 C C4  . NAG G 3 .   ? 249.730 197.644 196.720 1.00 92.80  ? 2    NAG G C4  1 
HETATM 9350 C C5  . NAG G 3 .   ? 249.798 196.161 197.072 1.00 92.80  ? 2    NAG G C5  1 
HETATM 9351 C C6  . NAG G 3 .   ? 251.093 195.510 196.647 1.00 92.80  ? 2    NAG G C6  1 
HETATM 9352 C C7  . NAG G 3 .   ? 246.991 199.026 200.540 1.00 92.80  ? 2    NAG G C7  1 
HETATM 9353 C C8  . NAG G 3 .   ? 245.631 199.526 200.922 1.00 92.80  ? 2    NAG G C8  1 
HETATM 9354 N N2  . NAG G 3 .   ? 247.104 198.513 199.311 1.00 92.80  ? 2    NAG G N2  1 
HETATM 9355 O O3  . NAG G 3 .   ? 248.463 199.670 197.065 1.00 92.80  ? 2    NAG G O3  1 
HETATM 9356 O O4  . NAG G 3 .   ? 249.756 197.792 195.305 1.00 92.80  ? 2    NAG G O4  1 
HETATM 9357 O O5  . NAG G 3 .   ? 249.697 195.991 198.494 1.00 92.80  ? 2    NAG G O5  1 
HETATM 9358 O O6  . NAG G 3 .   ? 252.180 195.940 197.454 1.00 92.80  ? 2    NAG G O6  1 
HETATM 9359 O O7  . NAG G 3 .   ? 247.945 199.083 201.310 1.00 92.80  ? 2    NAG G O7  1 
HETATM 9360 C C1  . NAG H 3 .   ? 267.849 191.165 204.295 1.00 124.85 ? 1    NAG H C1  1 
HETATM 9361 C C2  . NAG H 3 .   ? 266.413 191.469 203.861 1.00 124.85 ? 1    NAG H C2  1 
HETATM 9362 C C3  . NAG H 3 .   ? 266.383 192.019 202.433 1.00 124.85 ? 1    NAG H C3  1 
HETATM 9363 C C4  . NAG H 3 .   ? 267.191 191.142 201.483 1.00 124.85 ? 1    NAG H C4  1 
HETATM 9364 C C5  . NAG H 3 .   ? 268.568 190.836 202.063 1.00 124.85 ? 1    NAG H C5  1 
HETATM 9365 C C6  . NAG H 3 .   ? 269.700 191.229 201.142 1.00 124.85 ? 1    NAG H C6  1 
HETATM 9366 C C7  . NAG H 3 .   ? 265.011 189.889 205.113 1.00 124.85 ? 1    NAG H C7  1 
HETATM 9367 C C8  . NAG H 3 .   ? 264.179 188.645 205.037 1.00 124.85 ? 1    NAG H C8  1 
HETATM 9368 N N2  . NAG H 3 .   ? 265.576 190.286 203.968 1.00 124.85 ? 1    NAG H N2  1 
HETATM 9369 O O3  . NAG H 3 .   ? 266.898 193.345 202.426 1.00 124.85 ? 1    NAG H O3  1 
HETATM 9370 O O4  . NAG H 3 .   ? 266.501 189.918 201.257 1.00 124.85 ? 1    NAG H O4  1 
HETATM 9371 O O5  . NAG H 3 .   ? 268.751 191.571 203.279 1.00 124.85 ? 1    NAG H O5  1 
HETATM 9372 O O6  . NAG H 3 .   ? 269.225 191.548 199.841 1.00 124.85 ? 1    NAG H O6  1 
HETATM 9373 O O7  . NAG H 3 .   ? 265.165 190.506 206.162 1.00 124.85 ? 1    NAG H O7  1 
HETATM 9374 C C1  . NAG H 3 .   ? 266.461 189.648 199.840 1.00 128.31 ? 2    NAG H C1  1 
HETATM 9375 C C2  . NAG H 3 .   ? 265.335 188.647 199.589 1.00 128.31 ? 2    NAG H C2  1 
HETATM 9376 C C3  . NAG H 3 .   ? 264.554 189.015 198.324 1.00 128.31 ? 2    NAG H C3  1 
HETATM 9377 C C4  . NAG H 3 .   ? 265.477 189.503 197.211 1.00 128.31 ? 2    NAG H C4  1 
HETATM 9378 C C5  . NAG H 3 .   ? 266.388 190.631 197.693 1.00 128.31 ? 2    NAG H C5  1 
HETATM 9379 C C6  . NAG H 3 .   ? 266.093 191.954 197.026 1.00 128.31 ? 2    NAG H C6  1 
HETATM 9380 C C7  . NAG H 3 .   ? 266.055 186.510 200.560 1.00 128.31 ? 2    NAG H C7  1 
HETATM 9381 C C8  . NAG H 3 .   ? 266.595 185.141 200.279 1.00 128.31 ? 2    NAG H C8  1 
HETATM 9382 N N2  . NAG H 3 .   ? 265.854 187.292 199.494 1.00 128.31 ? 2    NAG H N2  1 
HETATM 9383 O O3  . NAG H 3 .   ? 263.597 190.020 198.636 1.00 128.31 ? 2    NAG H O3  1 
HETATM 9384 O O4  . NAG H 3 .   ? 266.277 188.426 196.737 1.00 128.31 ? 2    NAG H O4  1 
HETATM 9385 O O5  . NAG H 3 .   ? 266.217 190.831 199.101 1.00 128.31 ? 2    NAG H O5  1 
HETATM 9386 O O6  . NAG H 3 .   ? 264.720 192.064 196.675 1.00 128.31 ? 2    NAG H O6  1 
HETATM 9387 O O7  . NAG H 3 .   ? 265.811 186.892 201.700 1.00 128.31 ? 2    NAG H O7  1 
HETATM 9388 C C1  . NAG I 3 .   ? 233.462 162.586 221.342 1.00 100.20 ? 1    NAG I C1  1 
HETATM 9389 C C2  . NAG I 3 .   ? 234.100 162.484 222.723 1.00 100.20 ? 1    NAG I C2  1 
HETATM 9390 C C3  . NAG I 3 .   ? 233.660 161.194 223.420 1.00 100.20 ? 1    NAG I C3  1 
HETATM 9391 C C4  . NAG I 3 .   ? 233.363 160.082 222.417 1.00 100.20 ? 1    NAG I C4  1 
HETATM 9392 C C5  . NAG I 3 .   ? 232.326 160.514 221.379 1.00 100.20 ? 1    NAG I C5  1 
HETATM 9393 C C6  . NAG I 3 .   ? 230.946 159.964 221.658 1.00 100.20 ? 1    NAG I C6  1 
HETATM 9394 C C7  . NAG I 3 .   ? 236.328 162.890 223.669 1.00 100.20 ? 1    NAG I C7  1 
HETATM 9395 C C8  . NAG I 3 .   ? 237.804 162.900 223.405 1.00 100.20 ? 1    NAG I C8  1 
HETATM 9396 N N2  . NAG I 3 .   ? 235.550 162.548 222.637 1.00 100.20 ? 1    NAG I N2  1 
HETATM 9397 O O3  . NAG I 3 .   ? 232.506 161.454 224.211 1.00 100.20 ? 1    NAG I O3  1 
HETATM 9398 O O4  . NAG I 3 .   ? 234.562 159.694 221.753 1.00 100.20 ? 1    NAG I O4  1 
HETATM 9399 O O5  . NAG I 3 .   ? 232.204 161.943 221.355 1.00 100.20 ? 1    NAG I O5  1 
HETATM 9400 O O6  . NAG I 3 .   ? 231.004 158.809 222.483 1.00 100.20 ? 1    NAG I O6  1 
HETATM 9401 O O7  . NAG I 3 .   ? 235.862 163.181 224.766 1.00 100.20 ? 1    NAG I O7  1 
HETATM 9402 C C1  . NAG I 3 .   ? 234.385 158.413 221.117 1.00 103.13 ? 2    NAG I C1  1 
HETATM 9403 C C2  . NAG I 3 .   ? 234.996 158.470 219.716 1.00 103.13 ? 2    NAG I C2  1 
HETATM 9404 C C3  . NAG I 3 .   ? 234.889 157.108 219.036 1.00 103.13 ? 2    NAG I C3  1 
HETATM 9405 C C4  . NAG I 3 .   ? 235.491 156.023 219.918 1.00 103.13 ? 2    NAG I C4  1 
HETATM 9406 C C5  . NAG I 3 .   ? 234.857 156.061 221.305 1.00 103.13 ? 2    NAG I C5  1 
HETATM 9407 C C6  . NAG I 3 .   ? 235.490 155.087 222.272 1.00 103.13 ? 2    NAG I C6  1 
HETATM 9408 C C7  . NAG I 3 .   ? 234.887 160.705 218.707 1.00 103.13 ? 2    NAG I C7  1 
HETATM 9409 C C8  . NAG I 3 .   ? 234.092 161.637 217.842 1.00 103.13 ? 2    NAG I C8  1 
HETATM 9410 N N2  . NAG I 3 .   ? 234.357 159.495 218.907 1.00 103.13 ? 2    NAG I N2  1 
HETATM 9411 O O3  . NAG I 3 .   ? 235.565 157.149 217.784 1.00 103.13 ? 2    NAG I O3  1 
HETATM 9412 O O4  . NAG I 3 .   ? 235.270 154.743 219.336 1.00 103.13 ? 2    NAG I O4  1 
HETATM 9413 O O5  . NAG I 3 .   ? 235.012 157.369 221.875 1.00 103.13 ? 2    NAG I O5  1 
HETATM 9414 O O6  . NAG I 3 .   ? 236.700 154.551 221.753 1.00 103.13 ? 2    NAG I O6  1 
HETATM 9415 O O7  . NAG I 3 .   ? 235.960 161.034 219.203 1.00 103.13 ? 2    NAG I O7  1 
HETATM 9416 C C1  . NAG J 3 .   ? 232.979 217.486 190.302 1.00 80.10  ? 1    NAG J C1  1 
HETATM 9417 C C2  . NAG J 3 .   ? 232.074 217.241 191.507 1.00 80.10  ? 1    NAG J C2  1 
HETATM 9418 C C3  . NAG J 3 .   ? 231.205 218.467 191.772 1.00 80.10  ? 1    NAG J C3  1 
HETATM 9419 C C4  . NAG J 3 .   ? 232.067 219.716 191.901 1.00 80.10  ? 1    NAG J C4  1 
HETATM 9420 C C5  . NAG J 3 .   ? 232.981 219.856 190.686 1.00 80.10  ? 1    NAG J C5  1 
HETATM 9421 C C6  . NAG J 3 .   ? 233.958 221.002 190.808 1.00 80.10  ? 1    NAG J C6  1 
HETATM 9422 C C7  . NAG J 3 .   ? 230.858 215.265 192.309 1.00 80.10  ? 1    NAG J C7  1 
HETATM 9423 C C8  . NAG J 3 .   ? 230.009 214.093 191.923 1.00 80.10  ? 1    NAG J C8  1 
HETATM 9424 N N2  . NAG J 3 .   ? 231.247 216.062 191.308 1.00 80.10  ? 1    NAG J N2  1 
HETATM 9425 O O3  . NAG J 3 .   ? 230.455 218.268 192.965 1.00 80.10  ? 1    NAG J O3  1 
HETATM 9426 O O4  . NAG J 3 .   ? 231.239 220.870 191.994 1.00 80.10  ? 1    NAG J O4  1 
HETATM 9427 O O5  . NAG J 3 .   ? 233.762 218.664 190.520 1.00 80.10  ? 1    NAG J O5  1 
HETATM 9428 O O6  . NAG J 3 .   ? 234.461 221.116 192.133 1.00 80.10  ? 1    NAG J O6  1 
HETATM 9429 O O7  . NAG J 3 .   ? 231.177 215.482 193.473 1.00 80.10  ? 1    NAG J O7  1 
HETATM 9430 C C1  . NAG J 3 .   ? 231.320 221.415 193.326 1.00 93.08  ? 2    NAG J C1  1 
HETATM 9431 C C2  . NAG J 3 .   ? 231.250 222.939 193.231 1.00 93.08  ? 2    NAG J C2  1 
HETATM 9432 C C3  . NAG J 3 .   ? 231.275 223.556 194.626 1.00 93.08  ? 2    NAG J C3  1 
HETATM 9433 C C4  . NAG J 3 .   ? 230.181 222.951 195.495 1.00 93.08  ? 2    NAG J C4  1 
HETATM 9434 C C5  . NAG J 3 .   ? 230.292 221.429 195.499 1.00 93.08  ? 2    NAG J C5  1 
HETATM 9435 C C6  . NAG J 3 .   ? 229.164 220.756 196.246 1.00 93.08  ? 2    NAG J C6  1 
HETATM 9436 C C7  . NAG J 3 .   ? 232.205 224.515 191.610 1.00 93.08  ? 2    NAG J C7  1 
HETATM 9437 C C8  . NAG J 3 .   ? 233.432 224.919 190.849 1.00 93.08  ? 2    NAG J C8  1 
HETATM 9438 N N2  . NAG J 3 .   ? 232.339 223.461 192.421 1.00 93.08  ? 2    NAG J N2  1 
HETATM 9439 O O3  . NAG J 3 .   ? 231.093 224.964 194.525 1.00 93.08  ? 2    NAG J O3  1 
HETATM 9440 O O4  . NAG J 3 .   ? 230.295 223.434 196.829 1.00 93.08  ? 2    NAG J O4  1 
HETATM 9441 O O5  . NAG J 3 .   ? 230.251 220.934 194.152 1.00 93.08  ? 2    NAG J O5  1 
HETATM 9442 O O6  . NAG J 3 .   ? 228.608 221.616 197.231 1.00 93.08  ? 2    NAG J O6  1 
HETATM 9443 O O7  . NAG J 3 .   ? 231.142 225.116 191.495 1.00 93.08  ? 2    NAG J O7  1 
HETATM 9444 C C1  . NAG K 4 .   ? 230.636 213.318 214.401 1.00 86.09  ? 1    NAG K C1  1 
HETATM 9445 C C2  . NAG K 4 .   ? 231.420 212.781 215.591 1.00 86.09  ? 1    NAG K C2  1 
HETATM 9446 C C3  . NAG K 4 .   ? 231.427 213.808 216.719 1.00 86.09  ? 1    NAG K C3  1 
HETATM 9447 C C4  . NAG K 4 .   ? 231.920 215.160 216.215 1.00 86.09  ? 1    NAG K C4  1 
HETATM 9448 C C5  . NAG K 4 .   ? 231.151 215.584 214.964 1.00 86.09  ? 1    NAG K C5  1 
HETATM 9449 C C6  . NAG K 4 .   ? 231.708 216.834 214.324 1.00 86.09  ? 1    NAG K C6  1 
HETATM 9450 C C7  . NAG K 4 .   ? 231.328 210.329 215.649 1.00 86.09  ? 1    NAG K C7  1 
HETATM 9451 C C8  . NAG K 4 .   ? 230.640 209.129 216.224 1.00 86.09  ? 1    NAG K C8  1 
HETATM 9452 N N2  . NAG K 4 .   ? 230.867 211.518 216.053 1.00 86.09  ? 1    NAG K N2  1 
HETATM 9453 O O3  . NAG K 4 .   ? 232.265 213.347 217.773 1.00 86.09  ? 1    NAG K O3  1 
HETATM 9454 O O4  . NAG K 4 .   ? 231.712 216.145 217.221 1.00 86.09  ? 1    NAG K O4  1 
HETATM 9455 O O5  . NAG K 4 .   ? 231.208 214.550 213.969 1.00 86.09  ? 1    NAG K O5  1 
HETATM 9456 O O6  . NAG K 4 .   ? 233.022 216.621 213.825 1.00 86.09  ? 1    NAG K O6  1 
HETATM 9457 O O7  . NAG K 4 .   ? 232.258 210.228 214.856 1.00 86.09  ? 1    NAG K O7  1 
HETATM 9458 C C1  . NAG K 4 .   ? 232.961 216.580 217.795 1.00 106.59 ? 2    NAG K C1  1 
HETATM 9459 C C2  . NAG K 4 .   ? 232.694 216.925 219.263 1.00 106.59 ? 2    NAG K C2  1 
HETATM 9460 C C3  . NAG K 4 .   ? 233.985 217.350 219.958 1.00 106.59 ? 2    NAG K C3  1 
HETATM 9461 C C4  . NAG K 4 .   ? 235.065 216.293 219.763 1.00 106.59 ? 2    NAG K C4  1 
HETATM 9462 C C5  . NAG K 4 .   ? 235.242 215.988 218.277 1.00 106.59 ? 2    NAG K C5  1 
HETATM 9463 C C6  . NAG K 4 .   ? 236.222 214.868 218.016 1.00 106.59 ? 2    NAG K C6  1 
HETATM 9464 C C7  . NAG K 4 .   ? 231.771 219.193 218.900 1.00 106.59 ? 2    NAG K C7  1 
HETATM 9465 C C8  . NAG K 4 .   ? 230.599 220.093 219.151 1.00 106.59 ? 2    NAG K C8  1 
HETATM 9466 N N2  . NAG K 4 .   ? 231.670 217.952 219.396 1.00 106.59 ? 2    NAG K N2  1 
HETATM 9467 O O3  . NAG K 4 .   ? 233.736 217.541 221.346 1.00 106.59 ? 2    NAG K O3  1 
HETATM 9468 O O4  . NAG K 4 .   ? 236.303 216.721 220.323 1.00 106.59 ? 2    NAG K O4  1 
HETATM 9469 O O5  . NAG K 4 .   ? 233.987 215.578 217.713 1.00 106.59 ? 2    NAG K O5  1 
HETATM 9470 O O6  . NAG K 4 .   ? 235.784 213.648 218.598 1.00 106.59 ? 2    NAG K O6  1 
HETATM 9471 O O7  . NAG K 4 .   ? 232.759 219.575 218.278 1.00 106.59 ? 2    NAG K O7  1 
HETATM 9472 C C1  . BMA K 4 .   ? 236.668 218.044 219.870 1.00 120.48 ? 3    BMA K C1  1 
HETATM 9473 C C2  . BMA K 4 .   ? 237.059 218.885 221.113 1.00 120.48 ? 3    BMA K C2  1 
HETATM 9474 C C3  . BMA K 4 .   ? 237.609 220.244 220.680 1.00 120.48 ? 3    BMA K C3  1 
HETATM 9475 C C4  . BMA K 4 .   ? 238.688 220.094 219.596 1.00 120.48 ? 3    BMA K C4  1 
HETATM 9476 C C5  . BMA K 4 .   ? 238.136 219.270 218.424 1.00 120.48 ? 3    BMA K C5  1 
HETATM 9477 C C6  . BMA K 4 .   ? 239.158 219.047 217.325 1.00 120.48 ? 3    BMA K C6  1 
HETATM 9478 O O2  . BMA K 4 .   ? 238.088 218.243 221.852 1.00 120.48 ? 3    BMA K O2  1 
HETATM 9479 O O3  . BMA K 4 .   ? 238.128 220.973 221.786 1.00 120.48 ? 3    BMA K O3  1 
HETATM 9480 O O4  . BMA K 4 .   ? 239.091 221.372 219.131 1.00 120.48 ? 3    BMA K O4  1 
HETATM 9481 O O5  . BMA K 4 .   ? 237.735 217.986 218.930 1.00 120.48 ? 3    BMA K O5  1 
HETATM 9482 O O6  . BMA K 4 .   ? 240.164 218.174 217.822 1.00 120.48 ? 3    BMA K O6  1 
HETATM 9483 C C1  . NAG L 5 .   ? 245.197 235.616 159.645 1.00 80.83  ? 701  NAG D C1  1 
HETATM 9484 C C2  . NAG L 5 .   ? 245.172 235.593 161.172 1.00 80.83  ? 701  NAG D C2  1 
HETATM 9485 C C3  . NAG L 5 .   ? 246.512 236.063 161.729 1.00 80.83  ? 701  NAG D C3  1 
HETATM 9486 C C4  . NAG L 5 .   ? 247.651 235.249 161.130 1.00 80.83  ? 701  NAG D C4  1 
HETATM 9487 C C5  . NAG L 5 .   ? 247.578 235.282 159.606 1.00 80.83  ? 701  NAG D C5  1 
HETATM 9488 C C6  . NAG L 5 .   ? 248.606 234.393 158.945 1.00 80.83  ? 701  NAG D C6  1 
HETATM 9489 C C7  . NAG L 5 .   ? 243.186 235.961 162.566 1.00 80.83  ? 701  NAG D C7  1 
HETATM 9490 C C8  . NAG L 5 .   ? 242.136 236.942 162.993 1.00 80.83  ? 701  NAG D C8  1 
HETATM 9491 N N2  . NAG L 5 .   ? 244.088 236.413 161.689 1.00 80.83  ? 701  NAG D N2  1 
HETATM 9492 O O3  . NAG L 5 .   ? 246.511 235.927 163.146 1.00 80.83  ? 701  NAG D O3  1 
HETATM 9493 O O4  . NAG L 5 .   ? 248.903 235.780 161.551 1.00 80.83  ? 701  NAG D O4  1 
HETATM 9494 O O5  . NAG L 5 .   ? 246.290 234.821 159.169 1.00 80.83  ? 701  NAG D O5  1 
HETATM 9495 O O6  . NAG L 5 .   ? 248.715 233.143 159.611 1.00 80.83  ? 701  NAG D O6  1 
HETATM 9496 O O7  . NAG L 5 .   ? 243.216 234.813 162.996 1.00 80.83  ? 701  NAG D O7  1 
HETATM 9497 C C1  . NAG M 5 .   ? 229.364 206.212 134.551 1.00 69.20  ? 702  NAG D C1  1 
HETATM 9498 C C2  . NAG M 5 .   ? 230.074 204.911 134.178 1.00 69.20  ? 702  NAG D C2  1 
HETATM 9499 C C3  . NAG M 5 .   ? 229.175 204.054 133.291 1.00 69.20  ? 702  NAG D C3  1 
HETATM 9500 C C4  . NAG M 5 .   ? 227.820 203.842 133.952 1.00 69.20  ? 702  NAG D C4  1 
HETATM 9501 C C5  . NAG M 5 .   ? 227.205 205.184 134.340 1.00 69.20  ? 702  NAG D C5  1 
HETATM 9502 C C6  . NAG M 5 .   ? 225.914 205.042 135.112 1.00 69.20  ? 702  NAG D C6  1 
HETATM 9503 C C7  . NAG M 5 .   ? 232.409 204.383 133.634 1.00 69.20  ? 702  NAG D C7  1 
HETATM 9504 C C8  . NAG M 5 .   ? 233.633 204.811 132.883 1.00 69.20  ? 702  NAG D C8  1 
HETATM 9505 N N2  . NAG M 5 .   ? 231.341 205.179 133.516 1.00 69.20  ? 702  NAG D N2  1 
HETATM 9506 O O3  . NAG M 5 .   ? 229.801 202.799 133.051 1.00 69.20  ? 702  NAG D O3  1 
HETATM 9507 O O4  . NAG M 5 .   ? 226.944 203.164 133.060 1.00 69.20  ? 702  NAG D O4  1 
HETATM 9508 O O5  . NAG M 5 .   ? 228.112 205.913 135.180 1.00 69.20  ? 702  NAG D O5  1 
HETATM 9509 O O6  . NAG M 5 .   ? 225.845 205.972 136.183 1.00 69.20  ? 702  NAG D O6  1 
HETATM 9510 O O7  . NAG M 5 .   ? 232.388 203.364 134.317 1.00 69.20  ? 702  NAG D O7  1 
HETATM 9511 C C1  . NAG N 5 .   ? 214.698 232.440 171.116 1.00 73.03  ? 703  NAG D C1  1 
HETATM 9512 C C2  . NAG N 5 .   ? 213.779 231.420 171.785 1.00 73.03  ? 703  NAG D C2  1 
HETATM 9513 C C3  . NAG N 5 .   ? 212.741 232.132 172.648 1.00 73.03  ? 703  NAG D C3  1 
HETATM 9514 C C4  . NAG N 5 .   ? 213.422 233.074 173.632 1.00 73.03  ? 703  NAG D C4  1 
HETATM 9515 C C5  . NAG N 5 .   ? 214.357 234.025 172.890 1.00 73.03  ? 703  NAG D C5  1 
HETATM 9516 C C6  . NAG N 5 .   ? 215.160 234.908 173.817 1.00 73.03  ? 703  NAG D C6  1 
HETATM 9517 C C7  . NAG N 5 .   ? 213.428 229.284 170.622 1.00 73.03  ? 703  NAG D C7  1 
HETATM 9518 C C8  . NAG N 5 .   ? 214.494 228.727 171.517 1.00 73.03  ? 703  NAG D C8  1 
HETATM 9519 N N2  . NAG N 5 .   ? 213.129 230.576 170.796 1.00 73.03  ? 703  NAG D N2  1 
HETATM 9520 O O3  . NAG N 5 .   ? 211.969 231.167 173.354 1.00 73.03  ? 703  NAG D O3  1 
HETATM 9521 O O4  . NAG N 5 .   ? 212.446 233.832 174.337 1.00 73.03  ? 703  NAG D O4  1 
HETATM 9522 O O5  . NAG N 5 .   ? 215.301 233.274 172.113 1.00 73.03  ? 703  NAG D O5  1 
HETATM 9523 O O6  . NAG N 5 .   ? 216.546 234.864 173.504 1.00 73.03  ? 703  NAG D O6  1 
HETATM 9524 O O7  . NAG N 5 .   ? 212.863 228.595 169.778 1.00 73.03  ? 703  NAG D O7  1 
HETATM 9525 C C1  . NAG O 5 .   ? 196.495 258.286 143.821 1.00 88.75  ? 704  NAG D C1  1 
HETATM 9526 C C2  . NAG O 5 .   ? 195.998 258.278 142.376 1.00 88.75  ? 704  NAG D C2  1 
HETATM 9527 C C3  . NAG O 5 .   ? 195.391 259.632 142.019 1.00 88.75  ? 704  NAG D C3  1 
HETATM 9528 C C4  . NAG O 5 .   ? 194.319 260.018 143.029 1.00 88.75  ? 704  NAG D C4  1 
HETATM 9529 C C5  . NAG O 5 .   ? 194.882 259.956 144.446 1.00 88.75  ? 704  NAG D C5  1 
HETATM 9530 C C6  . NAG O 5 .   ? 193.839 260.210 145.509 1.00 88.75  ? 704  NAG D C6  1 
HETATM 9531 C C7  . NAG O 5 .   ? 197.276 256.703 140.995 1.00 88.75  ? 704  NAG D C7  1 
HETATM 9532 C C8  . NAG O 5 .   ? 198.431 256.536 140.054 1.00 88.75  ? 704  NAG D C8  1 
HETATM 9533 N N2  . NAG O 5 .   ? 197.072 257.941 141.457 1.00 88.75  ? 704  NAG D N2  1 
HETATM 9534 O O3  . NAG O 5 .   ? 194.830 259.570 140.713 1.00 88.75  ? 704  NAG D O3  1 
HETATM 9535 O O4  . NAG O 5 .   ? 193.855 261.337 142.766 1.00 88.75  ? 704  NAG D O4  1 
HETATM 9536 O O5  . NAG O 5 .   ? 195.422 258.650 144.699 1.00 88.75  ? 704  NAG D O5  1 
HETATM 9537 O O6  . NAG O 5 .   ? 192.999 259.078 145.693 1.00 88.75  ? 704  NAG D O6  1 
HETATM 9538 O O7  . NAG O 5 .   ? 196.562 255.761 141.322 1.00 88.75  ? 704  NAG D O7  1 
HETATM 9539 C C1  . NAG P 5 .   ? 221.948 179.675 199.331 1.00 93.29  ? 1301 NAG C C1  1 
HETATM 9540 C C2  . NAG P 5 .   ? 221.850 180.020 197.845 1.00 93.29  ? 1301 NAG C C2  1 
HETATM 9541 C C3  . NAG P 5 .   ? 220.398 180.290 197.460 1.00 93.29  ? 1301 NAG C C3  1 
HETATM 9542 C C4  . NAG P 5 .   ? 219.512 179.122 197.874 1.00 93.29  ? 1301 NAG C C4  1 
HETATM 9543 C C5  . NAG P 5 .   ? 219.705 178.812 199.355 1.00 93.29  ? 1301 NAG C C5  1 
HETATM 9544 C C6  . NAG P 5 .   ? 218.946 177.586 199.807 1.00 93.29  ? 1301 NAG C C6  1 
HETATM 9545 C C7  . NAG P 5 .   ? 223.863 181.055 196.894 1.00 93.29  ? 1301 NAG C C7  1 
HETATM 9546 C C8  . NAG P 5 .   ? 224.591 182.339 196.635 1.00 93.29  ? 1301 NAG C C8  1 
HETATM 9547 N N2  . NAG P 5 .   ? 222.685 181.164 197.517 1.00 93.29  ? 1301 NAG C N2  1 
HETATM 9548 O O3  . NAG P 5 .   ? 220.310 180.493 196.054 1.00 93.29  ? 1301 NAG C O3  1 
HETATM 9549 O O4  . NAG P 5 .   ? 218.145 179.439 197.635 1.00 93.29  ? 1301 NAG C O4  1 
HETATM 9550 O O5  . NAG P 5 .   ? 221.092 178.563 199.625 1.00 93.29  ? 1301 NAG C O5  1 
HETATM 9551 O O6  . NAG P 5 .   ? 219.816 176.618 200.377 1.00 93.29  ? 1301 NAG C O6  1 
HETATM 9552 O O7  . NAG P 5 .   ? 224.319 179.968 196.553 1.00 93.29  ? 1301 NAG C O7  1 
HETATM 9553 C C1  . NAG Q 5 .   ? 229.719 188.568 190.130 1.00 96.69  ? 1302 NAG C C1  1 
HETATM 9554 C C2  . NAG Q 5 .   ? 229.092 188.580 188.736 1.00 96.69  ? 1302 NAG C C2  1 
HETATM 9555 C C3  . NAG Q 5 .   ? 227.622 188.982 188.823 1.00 96.69  ? 1302 NAG C C3  1 
HETATM 9556 C C4  . NAG Q 5 .   ? 226.885 188.092 189.814 1.00 96.69  ? 1302 NAG C C4  1 
HETATM 9557 C C5  . NAG Q 5 .   ? 227.602 188.094 191.161 1.00 96.69  ? 1302 NAG C C5  1 
HETATM 9558 C C6  . NAG Q 5 .   ? 226.992 187.134 192.156 1.00 96.69  ? 1302 NAG C C6  1 
HETATM 9559 C C7  . NAG Q 5 .   ? 230.593 189.045 186.846 1.00 96.69  ? 1302 NAG C C7  1 
HETATM 9560 C C8  . NAG Q 5 .   ? 230.689 187.558 186.675 1.00 96.69  ? 1302 NAG C C8  1 
HETATM 9561 N N2  . NAG Q 5 .   ? 229.815 189.474 187.846 1.00 96.69  ? 1302 NAG C N2  1 
HETATM 9562 O O3  . NAG Q 5 .   ? 227.025 188.876 187.535 1.00 96.69  ? 1302 NAG C O3  1 
HETATM 9563 O O4  . NAG Q 5 .   ? 225.552 188.559 189.991 1.00 96.69  ? 1302 NAG C O4  1 
HETATM 9564 O O5  . NAG Q 5 .   ? 228.970 187.697 190.988 1.00 96.69  ? 1302 NAG C O5  1 
HETATM 9565 O O6  . NAG Q 5 .   ? 225.586 187.024 191.976 1.00 96.69  ? 1302 NAG C O6  1 
HETATM 9566 O O7  . NAG Q 5 .   ? 231.192 189.823 186.110 1.00 96.69  ? 1302 NAG C O7  1 
HETATM 9567 C C1  . NAG R 5 .   ? 232.533 197.888 237.342 1.00 93.28  ? 1303 NAG C C1  1 
HETATM 9568 C C2  . NAG R 5 .   ? 233.849 197.197 237.701 1.00 93.28  ? 1303 NAG C C2  1 
HETATM 9569 C C3  . NAG R 5 .   ? 234.464 197.843 238.939 1.00 93.28  ? 1303 NAG C C3  1 
HETATM 9570 C C4  . NAG R 5 .   ? 234.597 199.347 238.745 1.00 93.28  ? 1303 NAG C C4  1 
HETATM 9571 C C5  . NAG R 5 .   ? 233.254 199.949 238.343 1.00 93.28  ? 1303 NAG C C5  1 
HETATM 9572 C C6  . NAG R 5 .   ? 233.339 201.422 238.016 1.00 93.28  ? 1303 NAG C C6  1 
HETATM 9573 C C7  . NAG R 5 .   ? 233.871 194.855 236.966 1.00 93.28  ? 1303 NAG C C7  1 
HETATM 9574 C C8  . NAG R 5 .   ? 233.613 193.432 237.357 1.00 93.28  ? 1303 NAG C C8  1 
HETATM 9575 N N2  . NAG R 5 .   ? 233.649 195.773 237.912 1.00 93.28  ? 1303 NAG C N2  1 
HETATM 9576 O O3  . NAG R 5 .   ? 235.742 197.269 239.188 1.00 93.28  ? 1303 NAG C O3  1 
HETATM 9577 O O4  . NAG R 5 .   ? 235.041 199.956 239.952 1.00 93.28  ? 1303 NAG C O4  1 
HETATM 9578 O O5  . NAG R 5 .   ? 232.759 199.292 237.167 1.00 93.28  ? 1303 NAG C O5  1 
HETATM 9579 O O6  . NAG R 5 .   ? 232.242 201.840 237.215 1.00 93.28  ? 1303 NAG C O6  1 
HETATM 9580 O O7  . NAG R 5 .   ? 234.261 195.161 235.843 1.00 93.28  ? 1303 NAG C O7  1 
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