data_8Z5R
# 
_entry.id   8Z5R 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8Z5R         pdb_00008z5r 10.2210/pdb8z5r/pdb 
WWPDB D_1300047018 ?            ?                   
EMDB  EMD-39779    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-04-23 ? 
2 'EM metadata'     1 0 2025-04-23 ? 
3 FSC               1 0 2025-04-23 ? 
4 'Half map'        1 0 2025-04-23 1 
5 'Half map'        1 0 2025-04-23 2 
6 Image             1 0 2025-04-23 ? 
7 Mask              1 0 2025-04-23 1 
8 'Primary map'     1 0 2025-04-23 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1 1 'Structure model' repository 'Initial release' ? ? 
2 2 'EM metadata'     repository 'Initial release' ? ? 
3 3 FSC               repository 'Initial release' ? ? 
4 4 'Half map'        repository 'Initial release' ? ? 
5 5 'Half map'        repository 'Initial release' ? ? 
6 6 Image             repository 'Initial release' ? ? 
7 7 Mask              repository 'Initial release' ? ? 
8 8 'Primary map'     repository 'Initial release' ? ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8Z5R 
_pdbx_database_status.recvd_initial_deposition_date   2024-04-18 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBC 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        
'human phosphorylase kinase alpha/gamma/delta subcomplex - phosphorylation and Ca2+ bound state' 
_pdbx_database_related.db_id          EMD-39779 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              yankg@sustech.edu.cn 
_pdbx_contact_author.name_first         Kaige 
_pdbx_contact_author.name_last          Yan 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-4176-5109 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Ma, R.'  1 ? 
'Yan, K.' 2 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'Molecular basis for the regulation of human phosphorylase kinase by phosphorylation and Ca2+' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Ma, R.'  1 ? 
primary 'Yan, K.' 2 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform'    140108.688 1 ? ? ? ? 
2 polymer     man 'Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform' 45084.672  1 
2.7.11.19,2.7.11.1,2.7.11.26 ? ? ? 
3 polymer     man Calmodulin-3                                                                  18921.584  1 ? ? ? ? 
4 non-polymer syn "ADENOSINE-5'-TRIPHOSPHATE"                                                   507.181    1 ? ? ? ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
1 'Phosphorylase kinase alpha M subunit'                                                   
2 'PHK-gamma-M,Phosphorylase kinase subunit gamma-1,Serine/threonine-protein kinase PHKG1' 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no yes 
;MRSRSNSGVRLDGYARLVQQTILCHQNPVTGLLPASYDQKDAWVRDNVYSILAVWGLGLAYRKNADRDEDKAKAYELEQS
VVKLMRGLLHCMIRQVDKVE(SEP)FKY(SEP)Q(SEP)TKD(SEP)LHAKYNTKTCATVVGDDQWGHLQLDATSVYLLF
LAQMTASGLHIIHSLDEVNFIQNLVFYIEAAYKTADFGIWERGDKTNQGISELNAS(SEP)VGMAKAALEALDELDLFGV
KGGPQSVIHVLADEVQHCQ(SEP)ILNSLLPRASTSKEVDASLLSVVSFPAFAVEDSQLVELTKQEIITKLQGRYGCCRF
LRDGYKTPKEDPNRLYYEPAELKLFENIECEWPLFWTYFILDGVFSGNAEQVQEYKEALEAVLIKGKNGVPLLPELY
(SEP)VPPDRVDEEYQNPHTVDRVPMGKLPHMWGQSLYILGSLMAEGFLAPGEIDPLNRRFSTVPKPDVVVQVSILAETE
EIKTILKDKGIYVETIAEVYPIRVQPARIL(SEP)HIYSSLGCNNRMKLSGRPYRHMGVLGTSKLYDIRKTIFTFTPQFI
DQQQFYLALDNKMIVEMLRTDL(SEP)YLCSRWRMTGQPTITFPISHSMLDEDGTSLNSSILAALRKMQDGYFGGARVQT
GKLSEFLTTSCCTHLSFMDPGPEGKLY(SEP)EDYDDNYDYLESGNWMNDYDSTSHARCGDEVARYLDHLLAH(TPO)AP
HPKLAPTSQKGGLDRFQAAVQTTCDLM(SEP)LVTKAKELHVQNVHMYLPTKLFQA(SEP)RP(SEP)FNLLD(SEP)PH
PRQENQVP(SEP)VRVEIHLPRDQ(SEP)GEVDFKALVLQLKETSSLQEQADILYMLYTMKGPDWNTELYNERSATVREL
LTELYGKVGEIRHWGLIRYISGILRKKVEALDEACTDLLSHQKHL(TPO)VGLPPEPREKTISAPLPYEALTQLIDEASE
GDMSISILTQEIMVYLAMYMRTQPGLFAEMFRLRIGLIIQVMATELAHSLRCSAEEATEGLMNLSPSAMKNLLHHIL
(SEP)GKEFGVER(SEP)VRPTDSNV(SEP)PAI(SEP)IHEIGAVGA(TPO)KTER(TPO)GIMQLK(SEP)EIKQVEF
RRL(SEP)I(SEP)AE(SEP)Q(SEP)PGTSM(TPO)PSSGSFPSAYDQQSSKDSRQGQWQRRRRLDGALNRVPVGFYQK
VWKVLQKCHGLSVEGFVLPSSTTREMTPGEIKFSVHVESVLNRVPQPEYRQLLVEAILVLTMLADIEIHSIGSIIAVEKI
VHIANDLFLQEQKTLGADD(TPO)MLAKDPASGICTLLYDSAP(SEP)GRFGTMTYLSKAAATYVQEFLPH(SEP)ICAM
Q
;
;MRSRSNSGVRLDGYARLVQQTILCHQNPVTGLLPASYDQKDAWVRDNVYSILAVWGLGLAYRKNADRDEDKAKAYELEQS
VVKLMRGLLHCMIRQVDKVESFKYSQSTKDSLHAKYNTKTCATVVGDDQWGHLQLDATSVYLLFLAQMTASGLHIIHSLD
EVNFIQNLVFYIEAAYKTADFGIWERGDKTNQGISELNASSVGMAKAALEALDELDLFGVKGGPQSVIHVLADEVQHCQS
ILNSLLPRASTSKEVDASLLSVVSFPAFAVEDSQLVELTKQEIITKLQGRYGCCRFLRDGYKTPKEDPNRLYYEPAELKL
FENIECEWPLFWTYFILDGVFSGNAEQVQEYKEALEAVLIKGKNGVPLLPELYSVPPDRVDEEYQNPHTVDRVPMGKLPH
MWGQSLYILGSLMAEGFLAPGEIDPLNRRFSTVPKPDVVVQVSILAETEEIKTILKDKGIYVETIAEVYPIRVQPARILS
HIYSSLGCNNRMKLSGRPYRHMGVLGTSKLYDIRKTIFTFTPQFIDQQQFYLALDNKMIVEMLRTDLSYLCSRWRMTGQP
TITFPISHSMLDEDGTSLNSSILAALRKMQDGYFGGARVQTGKLSEFLTTSCCTHLSFMDPGPEGKLYSEDYDDNYDYLE
SGNWMNDYDSTSHARCGDEVARYLDHLLAHTAPHPKLAPTSQKGGLDRFQAAVQTTCDLMSLVTKAKELHVQNVHMYLPT
KLFQASRPSFNLLDSPHPRQENQVPSVRVEIHLPRDQSGEVDFKALVLQLKETSSLQEQADILYMLYTMKGPDWNTELYN
ERSATVRELLTELYGKVGEIRHWGLIRYISGILRKKVEALDEACTDLLSHQKHLTVGLPPEPREKTISAPLPYEALTQLI
DEASEGDMSISILTQEIMVYLAMYMRTQPGLFAEMFRLRIGLIIQVMATELAHSLRCSAEEATEGLMNLSPSAMKNLLHH
ILSGKEFGVERSVRPTDSNVSPAISIHEIGAVGATKTERTGIMQLKSEIKQVEFRRLSISAESQSPGTSMTPSSGSFPSA
YDQQSSKDSRQGQWQRRRRLDGALNRVPVGFYQKVWKVLQKCHGLSVEGFVLPSSTTREMTPGEIKFSVHVESVLNRVPQ
PEYRQLLVEAILVLTMLADIEIHSIGSIIAVEKIVHIANDLFLQEQKTLGADDTMLAKDPASGICTLLYDSAPSGRFGTM
TYLSKAAATYVQEFLPHSICAMQ
;
A ? 
2 'polypeptide(L)' no no  
;MTRDEALPDSHSAQDFYENYEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEVDILRK
VSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRALLEVICTLHKLNIVHRDLKPENILLDD
NMNIKLTDFGFSCQLEPGERLREVCGTPSYLAPEIIECSMNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLR
MIMSGNYQFGSPEWDDYSDTVKDLVSRFLVVQPQNRYTAEEALAHPFFQQYLVEEVRHFSPRGKFKVIALTVLASVRIYY
QYRRVKPVTREIVIRDPYALRPLRRLIDAYAFRIYGHWVKKGQQQNRAALFENTPKAVLLSLAEEDY
;
;MTRDEALPDSHSAQDFYENYEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEVDILRK
VSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRALLEVICTLHKLNIVHRDLKPENILLDD
NMNIKLTDFGFSCQLEPGERLREVCGTPSYLAPEIIECSMNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLR
MIMSGNYQFGSPEWDDYSDTVKDLVSRFLVVQPQNRYTAEEALAHPFFQQYLVEEVRHFSPRGKFKVIALTVLASVRIYY
QYRRVKPVTREIVIRDPYALRPLRRLIDAYAFRIYGHWVKKGQQQNRAALFENTPKAVLLSLAEEDY
;
C ? 
3 'polypeptide(L)' no no  
;DYKDDDDKSGPDEVDASGRMADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGN
GTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEE
FVQMMTAK
;
;DYKDDDDKSGPDEVDASGRMADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGN
GTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEE
FVQMMTAK
;
D ? 
# 
_pdbx_entity_nonpoly.entity_id   4 
_pdbx_entity_nonpoly.name        "ADENOSINE-5'-TRIPHOSPHATE" 
_pdbx_entity_nonpoly.comp_id     ATP 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1    MET n 
1 2    ARG n 
1 3    SER n 
1 4    ARG n 
1 5    SER n 
1 6    ASN n 
1 7    SER n 
1 8    GLY n 
1 9    VAL n 
1 10   ARG n 
1 11   LEU n 
1 12   ASP n 
1 13   GLY n 
1 14   TYR n 
1 15   ALA n 
1 16   ARG n 
1 17   LEU n 
1 18   VAL n 
1 19   GLN n 
1 20   GLN n 
1 21   THR n 
1 22   ILE n 
1 23   LEU n 
1 24   CYS n 
1 25   HIS n 
1 26   GLN n 
1 27   ASN n 
1 28   PRO n 
1 29   VAL n 
1 30   THR n 
1 31   GLY n 
1 32   LEU n 
1 33   LEU n 
1 34   PRO n 
1 35   ALA n 
1 36   SER n 
1 37   TYR n 
1 38   ASP n 
1 39   GLN n 
1 40   LYS n 
1 41   ASP n 
1 42   ALA n 
1 43   TRP n 
1 44   VAL n 
1 45   ARG n 
1 46   ASP n 
1 47   ASN n 
1 48   VAL n 
1 49   TYR n 
1 50   SER n 
1 51   ILE n 
1 52   LEU n 
1 53   ALA n 
1 54   VAL n 
1 55   TRP n 
1 56   GLY n 
1 57   LEU n 
1 58   GLY n 
1 59   LEU n 
1 60   ALA n 
1 61   TYR n 
1 62   ARG n 
1 63   LYS n 
1 64   ASN n 
1 65   ALA n 
1 66   ASP n 
1 67   ARG n 
1 68   ASP n 
1 69   GLU n 
1 70   ASP n 
1 71   LYS n 
1 72   ALA n 
1 73   LYS n 
1 74   ALA n 
1 75   TYR n 
1 76   GLU n 
1 77   LEU n 
1 78   GLU n 
1 79   GLN n 
1 80   SER n 
1 81   VAL n 
1 82   VAL n 
1 83   LYS n 
1 84   LEU n 
1 85   MET n 
1 86   ARG n 
1 87   GLY n 
1 88   LEU n 
1 89   LEU n 
1 90   HIS n 
1 91   CYS n 
1 92   MET n 
1 93   ILE n 
1 94   ARG n 
1 95   GLN n 
1 96   VAL n 
1 97   ASP n 
1 98   LYS n 
1 99   VAL n 
1 100  GLU n 
1 101  SEP n 
1 102  PHE n 
1 103  LYS n 
1 104  TYR n 
1 105  SEP n 
1 106  GLN n 
1 107  SEP n 
1 108  THR n 
1 109  LYS n 
1 110  ASP n 
1 111  SEP n 
1 112  LEU n 
1 113  HIS n 
1 114  ALA n 
1 115  LYS n 
1 116  TYR n 
1 117  ASN n 
1 118  THR n 
1 119  LYS n 
1 120  THR n 
1 121  CYS n 
1 122  ALA n 
1 123  THR n 
1 124  VAL n 
1 125  VAL n 
1 126  GLY n 
1 127  ASP n 
1 128  ASP n 
1 129  GLN n 
1 130  TRP n 
1 131  GLY n 
1 132  HIS n 
1 133  LEU n 
1 134  GLN n 
1 135  LEU n 
1 136  ASP n 
1 137  ALA n 
1 138  THR n 
1 139  SER n 
1 140  VAL n 
1 141  TYR n 
1 142  LEU n 
1 143  LEU n 
1 144  PHE n 
1 145  LEU n 
1 146  ALA n 
1 147  GLN n 
1 148  MET n 
1 149  THR n 
1 150  ALA n 
1 151  SER n 
1 152  GLY n 
1 153  LEU n 
1 154  HIS n 
1 155  ILE n 
1 156  ILE n 
1 157  HIS n 
1 158  SER n 
1 159  LEU n 
1 160  ASP n 
1 161  GLU n 
1 162  VAL n 
1 163  ASN n 
1 164  PHE n 
1 165  ILE n 
1 166  GLN n 
1 167  ASN n 
1 168  LEU n 
1 169  VAL n 
1 170  PHE n 
1 171  TYR n 
1 172  ILE n 
1 173  GLU n 
1 174  ALA n 
1 175  ALA n 
1 176  TYR n 
1 177  LYS n 
1 178  THR n 
1 179  ALA n 
1 180  ASP n 
1 181  PHE n 
1 182  GLY n 
1 183  ILE n 
1 184  TRP n 
1 185  GLU n 
1 186  ARG n 
1 187  GLY n 
1 188  ASP n 
1 189  LYS n 
1 190  THR n 
1 191  ASN n 
1 192  GLN n 
1 193  GLY n 
1 194  ILE n 
1 195  SER n 
1 196  GLU n 
1 197  LEU n 
1 198  ASN n 
1 199  ALA n 
1 200  SER n 
1 201  SEP n 
1 202  VAL n 
1 203  GLY n 
1 204  MET n 
1 205  ALA n 
1 206  LYS n 
1 207  ALA n 
1 208  ALA n 
1 209  LEU n 
1 210  GLU n 
1 211  ALA n 
1 212  LEU n 
1 213  ASP n 
1 214  GLU n 
1 215  LEU n 
1 216  ASP n 
1 217  LEU n 
1 218  PHE n 
1 219  GLY n 
1 220  VAL n 
1 221  LYS n 
1 222  GLY n 
1 223  GLY n 
1 224  PRO n 
1 225  GLN n 
1 226  SER n 
1 227  VAL n 
1 228  ILE n 
1 229  HIS n 
1 230  VAL n 
1 231  LEU n 
1 232  ALA n 
1 233  ASP n 
1 234  GLU n 
1 235  VAL n 
1 236  GLN n 
1 237  HIS n 
1 238  CYS n 
1 239  GLN n 
1 240  SEP n 
1 241  ILE n 
1 242  LEU n 
1 243  ASN n 
1 244  SER n 
1 245  LEU n 
1 246  LEU n 
1 247  PRO n 
1 248  ARG n 
1 249  ALA n 
1 250  SER n 
1 251  THR n 
1 252  SER n 
1 253  LYS n 
1 254  GLU n 
1 255  VAL n 
1 256  ASP n 
1 257  ALA n 
1 258  SER n 
1 259  LEU n 
1 260  LEU n 
1 261  SER n 
1 262  VAL n 
1 263  VAL n 
1 264  SER n 
1 265  PHE n 
1 266  PRO n 
1 267  ALA n 
1 268  PHE n 
1 269  ALA n 
1 270  VAL n 
1 271  GLU n 
1 272  ASP n 
1 273  SER n 
1 274  GLN n 
1 275  LEU n 
1 276  VAL n 
1 277  GLU n 
1 278  LEU n 
1 279  THR n 
1 280  LYS n 
1 281  GLN n 
1 282  GLU n 
1 283  ILE n 
1 284  ILE n 
1 285  THR n 
1 286  LYS n 
1 287  LEU n 
1 288  GLN n 
1 289  GLY n 
1 290  ARG n 
1 291  TYR n 
1 292  GLY n 
1 293  CYS n 
1 294  CYS n 
1 295  ARG n 
1 296  PHE n 
1 297  LEU n 
1 298  ARG n 
1 299  ASP n 
1 300  GLY n 
1 301  TYR n 
1 302  LYS n 
1 303  THR n 
1 304  PRO n 
1 305  LYS n 
1 306  GLU n 
1 307  ASP n 
1 308  PRO n 
1 309  ASN n 
1 310  ARG n 
1 311  LEU n 
1 312  TYR n 
1 313  TYR n 
1 314  GLU n 
1 315  PRO n 
1 316  ALA n 
1 317  GLU n 
1 318  LEU n 
1 319  LYS n 
1 320  LEU n 
1 321  PHE n 
1 322  GLU n 
1 323  ASN n 
1 324  ILE n 
1 325  GLU n 
1 326  CYS n 
1 327  GLU n 
1 328  TRP n 
1 329  PRO n 
1 330  LEU n 
1 331  PHE n 
1 332  TRP n 
1 333  THR n 
1 334  TYR n 
1 335  PHE n 
1 336  ILE n 
1 337  LEU n 
1 338  ASP n 
1 339  GLY n 
1 340  VAL n 
1 341  PHE n 
1 342  SER n 
1 343  GLY n 
1 344  ASN n 
1 345  ALA n 
1 346  GLU n 
1 347  GLN n 
1 348  VAL n 
1 349  GLN n 
1 350  GLU n 
1 351  TYR n 
1 352  LYS n 
1 353  GLU n 
1 354  ALA n 
1 355  LEU n 
1 356  GLU n 
1 357  ALA n 
1 358  VAL n 
1 359  LEU n 
1 360  ILE n 
1 361  LYS n 
1 362  GLY n 
1 363  LYS n 
1 364  ASN n 
1 365  GLY n 
1 366  VAL n 
1 367  PRO n 
1 368  LEU n 
1 369  LEU n 
1 370  PRO n 
1 371  GLU n 
1 372  LEU n 
1 373  TYR n 
1 374  SEP n 
1 375  VAL n 
1 376  PRO n 
1 377  PRO n 
1 378  ASP n 
1 379  ARG n 
1 380  VAL n 
1 381  ASP n 
1 382  GLU n 
1 383  GLU n 
1 384  TYR n 
1 385  GLN n 
1 386  ASN n 
1 387  PRO n 
1 388  HIS n 
1 389  THR n 
1 390  VAL n 
1 391  ASP n 
1 392  ARG n 
1 393  VAL n 
1 394  PRO n 
1 395  MET n 
1 396  GLY n 
1 397  LYS n 
1 398  LEU n 
1 399  PRO n 
1 400  HIS n 
1 401  MET n 
1 402  TRP n 
1 403  GLY n 
1 404  GLN n 
1 405  SER n 
1 406  LEU n 
1 407  TYR n 
1 408  ILE n 
1 409  LEU n 
1 410  GLY n 
1 411  SER n 
1 412  LEU n 
1 413  MET n 
1 414  ALA n 
1 415  GLU n 
1 416  GLY n 
1 417  PHE n 
1 418  LEU n 
1 419  ALA n 
1 420  PRO n 
1 421  GLY n 
1 422  GLU n 
1 423  ILE n 
1 424  ASP n 
1 425  PRO n 
1 426  LEU n 
1 427  ASN n 
1 428  ARG n 
1 429  ARG n 
1 430  PHE n 
1 431  SER n 
1 432  THR n 
1 433  VAL n 
1 434  PRO n 
1 435  LYS n 
1 436  PRO n 
1 437  ASP n 
1 438  VAL n 
1 439  VAL n 
1 440  VAL n 
1 441  GLN n 
1 442  VAL n 
1 443  SER n 
1 444  ILE n 
1 445  LEU n 
1 446  ALA n 
1 447  GLU n 
1 448  THR n 
1 449  GLU n 
1 450  GLU n 
1 451  ILE n 
1 452  LYS n 
1 453  THR n 
1 454  ILE n 
1 455  LEU n 
1 456  LYS n 
1 457  ASP n 
1 458  LYS n 
1 459  GLY n 
1 460  ILE n 
1 461  TYR n 
1 462  VAL n 
1 463  GLU n 
1 464  THR n 
1 465  ILE n 
1 466  ALA n 
1 467  GLU n 
1 468  VAL n 
1 469  TYR n 
1 470  PRO n 
1 471  ILE n 
1 472  ARG n 
1 473  VAL n 
1 474  GLN n 
1 475  PRO n 
1 476  ALA n 
1 477  ARG n 
1 478  ILE n 
1 479  LEU n 
1 480  SEP n 
1 481  HIS n 
1 482  ILE n 
1 483  TYR n 
1 484  SER n 
1 485  SER n 
1 486  LEU n 
1 487  GLY n 
1 488  CYS n 
1 489  ASN n 
1 490  ASN n 
1 491  ARG n 
1 492  MET n 
1 493  LYS n 
1 494  LEU n 
1 495  SER n 
1 496  GLY n 
1 497  ARG n 
1 498  PRO n 
1 499  TYR n 
1 500  ARG n 
1 501  HIS n 
1 502  MET n 
1 503  GLY n 
1 504  VAL n 
1 505  LEU n 
1 506  GLY n 
1 507  THR n 
1 508  SER n 
1 509  LYS n 
1 510  LEU n 
1 511  TYR n 
1 512  ASP n 
1 513  ILE n 
1 514  ARG n 
1 515  LYS n 
1 516  THR n 
1 517  ILE n 
1 518  PHE n 
1 519  THR n 
1 520  PHE n 
1 521  THR n 
1 522  PRO n 
1 523  GLN n 
1 524  PHE n 
1 525  ILE n 
1 526  ASP n 
1 527  GLN n 
1 528  GLN n 
1 529  GLN n 
1 530  PHE n 
1 531  TYR n 
1 532  LEU n 
1 533  ALA n 
1 534  LEU n 
1 535  ASP n 
1 536  ASN n 
1 537  LYS n 
1 538  MET n 
1 539  ILE n 
1 540  VAL n 
1 541  GLU n 
1 542  MET n 
1 543  LEU n 
1 544  ARG n 
1 545  THR n 
1 546  ASP n 
1 547  LEU n 
1 548  SEP n 
1 549  TYR n 
1 550  LEU n 
1 551  CYS n 
1 552  SER n 
1 553  ARG n 
1 554  TRP n 
1 555  ARG n 
1 556  MET n 
1 557  THR n 
1 558  GLY n 
1 559  GLN n 
1 560  PRO n 
1 561  THR n 
1 562  ILE n 
1 563  THR n 
1 564  PHE n 
1 565  PRO n 
1 566  ILE n 
1 567  SER n 
1 568  HIS n 
1 569  SER n 
1 570  MET n 
1 571  LEU n 
1 572  ASP n 
1 573  GLU n 
1 574  ASP n 
1 575  GLY n 
1 576  THR n 
1 577  SER n 
1 578  LEU n 
1 579  ASN n 
1 580  SER n 
1 581  SER n 
1 582  ILE n 
1 583  LEU n 
1 584  ALA n 
1 585  ALA n 
1 586  LEU n 
1 587  ARG n 
1 588  LYS n 
1 589  MET n 
1 590  GLN n 
1 591  ASP n 
1 592  GLY n 
1 593  TYR n 
1 594  PHE n 
1 595  GLY n 
1 596  GLY n 
1 597  ALA n 
1 598  ARG n 
1 599  VAL n 
1 600  GLN n 
1 601  THR n 
1 602  GLY n 
1 603  LYS n 
1 604  LEU n 
1 605  SER n 
1 606  GLU n 
1 607  PHE n 
1 608  LEU n 
1 609  THR n 
1 610  THR n 
1 611  SER n 
1 612  CYS n 
1 613  CYS n 
1 614  THR n 
1 615  HIS n 
1 616  LEU n 
1 617  SER n 
1 618  PHE n 
1 619  MET n 
1 620  ASP n 
1 621  PRO n 
1 622  GLY n 
1 623  PRO n 
1 624  GLU n 
1 625  GLY n 
1 626  LYS n 
1 627  LEU n 
1 628  TYR n 
1 629  SEP n 
1 630  GLU n 
1 631  ASP n 
1 632  TYR n 
1 633  ASP n 
1 634  ASP n 
1 635  ASN n 
1 636  TYR n 
1 637  ASP n 
1 638  TYR n 
1 639  LEU n 
1 640  GLU n 
1 641  SER n 
1 642  GLY n 
1 643  ASN n 
1 644  TRP n 
1 645  MET n 
1 646  ASN n 
1 647  ASP n 
1 648  TYR n 
1 649  ASP n 
1 650  SER n 
1 651  THR n 
1 652  SER n 
1 653  HIS n 
1 654  ALA n 
1 655  ARG n 
1 656  CYS n 
1 657  GLY n 
1 658  ASP n 
1 659  GLU n 
1 660  VAL n 
1 661  ALA n 
1 662  ARG n 
1 663  TYR n 
1 664  LEU n 
1 665  ASP n 
1 666  HIS n 
1 667  LEU n 
1 668  LEU n 
1 669  ALA n 
1 670  HIS n 
1 671  TPO n 
1 672  ALA n 
1 673  PRO n 
1 674  HIS n 
1 675  PRO n 
1 676  LYS n 
1 677  LEU n 
1 678  ALA n 
1 679  PRO n 
1 680  THR n 
1 681  SER n 
1 682  GLN n 
1 683  LYS n 
1 684  GLY n 
1 685  GLY n 
1 686  LEU n 
1 687  ASP n 
1 688  ARG n 
1 689  PHE n 
1 690  GLN n 
1 691  ALA n 
1 692  ALA n 
1 693  VAL n 
1 694  GLN n 
1 695  THR n 
1 696  THR n 
1 697  CYS n 
1 698  ASP n 
1 699  LEU n 
1 700  MET n 
1 701  SEP n 
1 702  LEU n 
1 703  VAL n 
1 704  THR n 
1 705  LYS n 
1 706  ALA n 
1 707  LYS n 
1 708  GLU n 
1 709  LEU n 
1 710  HIS n 
1 711  VAL n 
1 712  GLN n 
1 713  ASN n 
1 714  VAL n 
1 715  HIS n 
1 716  MET n 
1 717  TYR n 
1 718  LEU n 
1 719  PRO n 
1 720  THR n 
1 721  LYS n 
1 722  LEU n 
1 723  PHE n 
1 724  GLN n 
1 725  ALA n 
1 726  SEP n 
1 727  ARG n 
1 728  PRO n 
1 729  SEP n 
1 730  PHE n 
1 731  ASN n 
1 732  LEU n 
1 733  LEU n 
1 734  ASP n 
1 735  SEP n 
1 736  PRO n 
1 737  HIS n 
1 738  PRO n 
1 739  ARG n 
1 740  GLN n 
1 741  GLU n 
1 742  ASN n 
1 743  GLN n 
1 744  VAL n 
1 745  PRO n 
1 746  SEP n 
1 747  VAL n 
1 748  ARG n 
1 749  VAL n 
1 750  GLU n 
1 751  ILE n 
1 752  HIS n 
1 753  LEU n 
1 754  PRO n 
1 755  ARG n 
1 756  ASP n 
1 757  GLN n 
1 758  SEP n 
1 759  GLY n 
1 760  GLU n 
1 761  VAL n 
1 762  ASP n 
1 763  PHE n 
1 764  LYS n 
1 765  ALA n 
1 766  LEU n 
1 767  VAL n 
1 768  LEU n 
1 769  GLN n 
1 770  LEU n 
1 771  LYS n 
1 772  GLU n 
1 773  THR n 
1 774  SER n 
1 775  SER n 
1 776  LEU n 
1 777  GLN n 
1 778  GLU n 
1 779  GLN n 
1 780  ALA n 
1 781  ASP n 
1 782  ILE n 
1 783  LEU n 
1 784  TYR n 
1 785  MET n 
1 786  LEU n 
1 787  TYR n 
1 788  THR n 
1 789  MET n 
1 790  LYS n 
1 791  GLY n 
1 792  PRO n 
1 793  ASP n 
1 794  TRP n 
1 795  ASN n 
1 796  THR n 
1 797  GLU n 
1 798  LEU n 
1 799  TYR n 
1 800  ASN n 
1 801  GLU n 
1 802  ARG n 
1 803  SER n 
1 804  ALA n 
1 805  THR n 
1 806  VAL n 
1 807  ARG n 
1 808  GLU n 
1 809  LEU n 
1 810  LEU n 
1 811  THR n 
1 812  GLU n 
1 813  LEU n 
1 814  TYR n 
1 815  GLY n 
1 816  LYS n 
1 817  VAL n 
1 818  GLY n 
1 819  GLU n 
1 820  ILE n 
1 821  ARG n 
1 822  HIS n 
1 823  TRP n 
1 824  GLY n 
1 825  LEU n 
1 826  ILE n 
1 827  ARG n 
1 828  TYR n 
1 829  ILE n 
1 830  SER n 
1 831  GLY n 
1 832  ILE n 
1 833  LEU n 
1 834  ARG n 
1 835  LYS n 
1 836  LYS n 
1 837  VAL n 
1 838  GLU n 
1 839  ALA n 
1 840  LEU n 
1 841  ASP n 
1 842  GLU n 
1 843  ALA n 
1 844  CYS n 
1 845  THR n 
1 846  ASP n 
1 847  LEU n 
1 848  LEU n 
1 849  SER n 
1 850  HIS n 
1 851  GLN n 
1 852  LYS n 
1 853  HIS n 
1 854  LEU n 
1 855  TPO n 
1 856  VAL n 
1 857  GLY n 
1 858  LEU n 
1 859  PRO n 
1 860  PRO n 
1 861  GLU n 
1 862  PRO n 
1 863  ARG n 
1 864  GLU n 
1 865  LYS n 
1 866  THR n 
1 867  ILE n 
1 868  SER n 
1 869  ALA n 
1 870  PRO n 
1 871  LEU n 
1 872  PRO n 
1 873  TYR n 
1 874  GLU n 
1 875  ALA n 
1 876  LEU n 
1 877  THR n 
1 878  GLN n 
1 879  LEU n 
1 880  ILE n 
1 881  ASP n 
1 882  GLU n 
1 883  ALA n 
1 884  SER n 
1 885  GLU n 
1 886  GLY n 
1 887  ASP n 
1 888  MET n 
1 889  SER n 
1 890  ILE n 
1 891  SER n 
1 892  ILE n 
1 893  LEU n 
1 894  THR n 
1 895  GLN n 
1 896  GLU n 
1 897  ILE n 
1 898  MET n 
1 899  VAL n 
1 900  TYR n 
1 901  LEU n 
1 902  ALA n 
1 903  MET n 
1 904  TYR n 
1 905  MET n 
1 906  ARG n 
1 907  THR n 
1 908  GLN n 
1 909  PRO n 
1 910  GLY n 
1 911  LEU n 
1 912  PHE n 
1 913  ALA n 
1 914  GLU n 
1 915  MET n 
1 916  PHE n 
1 917  ARG n 
1 918  LEU n 
1 919  ARG n 
1 920  ILE n 
1 921  GLY n 
1 922  LEU n 
1 923  ILE n 
1 924  ILE n 
1 925  GLN n 
1 926  VAL n 
1 927  MET n 
1 928  ALA n 
1 929  THR n 
1 930  GLU n 
1 931  LEU n 
1 932  ALA n 
1 933  HIS n 
1 934  SER n 
1 935  LEU n 
1 936  ARG n 
1 937  CYS n 
1 938  SER n 
1 939  ALA n 
1 940  GLU n 
1 941  GLU n 
1 942  ALA n 
1 943  THR n 
1 944  GLU n 
1 945  GLY n 
1 946  LEU n 
1 947  MET n 
1 948  ASN n 
1 949  LEU n 
1 950  SER n 
1 951  PRO n 
1 952  SER n 
1 953  ALA n 
1 954  MET n 
1 955  LYS n 
1 956  ASN n 
1 957  LEU n 
1 958  LEU n 
1 959  HIS n 
1 960  HIS n 
1 961  ILE n 
1 962  LEU n 
1 963  SEP n 
1 964  GLY n 
1 965  LYS n 
1 966  GLU n 
1 967  PHE n 
1 968  GLY n 
1 969  VAL n 
1 970  GLU n 
1 971  ARG n 
1 972  SEP n 
1 973  VAL n 
1 974  ARG n 
1 975  PRO n 
1 976  THR n 
1 977  ASP n 
1 978  SER n 
1 979  ASN n 
1 980  VAL n 
1 981  SEP n 
1 982  PRO n 
1 983  ALA n 
1 984  ILE n 
1 985  SEP n 
1 986  ILE n 
1 987  HIS n 
1 988  GLU n 
1 989  ILE n 
1 990  GLY n 
1 991  ALA n 
1 992  VAL n 
1 993  GLY n 
1 994  ALA n 
1 995  TPO n 
1 996  LYS n 
1 997  THR n 
1 998  GLU n 
1 999  ARG n 
1 1000 TPO n 
1 1001 GLY n 
1 1002 ILE n 
1 1003 MET n 
1 1004 GLN n 
1 1005 LEU n 
1 1006 LYS n 
1 1007 SEP n 
1 1008 GLU n 
1 1009 ILE n 
1 1010 LYS n 
1 1011 GLN n 
1 1012 VAL n 
1 1013 GLU n 
1 1014 PHE n 
1 1015 ARG n 
1 1016 ARG n 
1 1017 LEU n 
1 1018 SEP n 
1 1019 ILE n 
1 1020 SEP n 
1 1021 ALA n 
1 1022 GLU n 
1 1023 SEP n 
1 1024 GLN n 
1 1025 SEP n 
1 1026 PRO n 
1 1027 GLY n 
1 1028 THR n 
1 1029 SER n 
1 1030 MET n 
1 1031 TPO n 
1 1032 PRO n 
1 1033 SER n 
1 1034 SER n 
1 1035 GLY n 
1 1036 SER n 
1 1037 PHE n 
1 1038 PRO n 
1 1039 SER n 
1 1040 ALA n 
1 1041 TYR n 
1 1042 ASP n 
1 1043 GLN n 
1 1044 GLN n 
1 1045 SER n 
1 1046 SER n 
1 1047 LYS n 
1 1048 ASP n 
1 1049 SER n 
1 1050 ARG n 
1 1051 GLN n 
1 1052 GLY n 
1 1053 GLN n 
1 1054 TRP n 
1 1055 GLN n 
1 1056 ARG n 
1 1057 ARG n 
1 1058 ARG n 
1 1059 ARG n 
1 1060 LEU n 
1 1061 ASP n 
1 1062 GLY n 
1 1063 ALA n 
1 1064 LEU n 
1 1065 ASN n 
1 1066 ARG n 
1 1067 VAL n 
1 1068 PRO n 
1 1069 VAL n 
1 1070 GLY n 
1 1071 PHE n 
1 1072 TYR n 
1 1073 GLN n 
1 1074 LYS n 
1 1075 VAL n 
1 1076 TRP n 
1 1077 LYS n 
1 1078 VAL n 
1 1079 LEU n 
1 1080 GLN n 
1 1081 LYS n 
1 1082 CYS n 
1 1083 HIS n 
1 1084 GLY n 
1 1085 LEU n 
1 1086 SER n 
1 1087 VAL n 
1 1088 GLU n 
1 1089 GLY n 
1 1090 PHE n 
1 1091 VAL n 
1 1092 LEU n 
1 1093 PRO n 
1 1094 SER n 
1 1095 SER n 
1 1096 THR n 
1 1097 THR n 
1 1098 ARG n 
1 1099 GLU n 
1 1100 MET n 
1 1101 THR n 
1 1102 PRO n 
1 1103 GLY n 
1 1104 GLU n 
1 1105 ILE n 
1 1106 LYS n 
1 1107 PHE n 
1 1108 SER n 
1 1109 VAL n 
1 1110 HIS n 
1 1111 VAL n 
1 1112 GLU n 
1 1113 SER n 
1 1114 VAL n 
1 1115 LEU n 
1 1116 ASN n 
1 1117 ARG n 
1 1118 VAL n 
1 1119 PRO n 
1 1120 GLN n 
1 1121 PRO n 
1 1122 GLU n 
1 1123 TYR n 
1 1124 ARG n 
1 1125 GLN n 
1 1126 LEU n 
1 1127 LEU n 
1 1128 VAL n 
1 1129 GLU n 
1 1130 ALA n 
1 1131 ILE n 
1 1132 LEU n 
1 1133 VAL n 
1 1134 LEU n 
1 1135 THR n 
1 1136 MET n 
1 1137 LEU n 
1 1138 ALA n 
1 1139 ASP n 
1 1140 ILE n 
1 1141 GLU n 
1 1142 ILE n 
1 1143 HIS n 
1 1144 SER n 
1 1145 ILE n 
1 1146 GLY n 
1 1147 SER n 
1 1148 ILE n 
1 1149 ILE n 
1 1150 ALA n 
1 1151 VAL n 
1 1152 GLU n 
1 1153 LYS n 
1 1154 ILE n 
1 1155 VAL n 
1 1156 HIS n 
1 1157 ILE n 
1 1158 ALA n 
1 1159 ASN n 
1 1160 ASP n 
1 1161 LEU n 
1 1162 PHE n 
1 1163 LEU n 
1 1164 GLN n 
1 1165 GLU n 
1 1166 GLN n 
1 1167 LYS n 
1 1168 THR n 
1 1169 LEU n 
1 1170 GLY n 
1 1171 ALA n 
1 1172 ASP n 
1 1173 ASP n 
1 1174 TPO n 
1 1175 MET n 
1 1176 LEU n 
1 1177 ALA n 
1 1178 LYS n 
1 1179 ASP n 
1 1180 PRO n 
1 1181 ALA n 
1 1182 SER n 
1 1183 GLY n 
1 1184 ILE n 
1 1185 CYS n 
1 1186 THR n 
1 1187 LEU n 
1 1188 LEU n 
1 1189 TYR n 
1 1190 ASP n 
1 1191 SER n 
1 1192 ALA n 
1 1193 PRO n 
1 1194 SEP n 
1 1195 GLY n 
1 1196 ARG n 
1 1197 PHE n 
1 1198 GLY n 
1 1199 THR n 
1 1200 MET n 
1 1201 THR n 
1 1202 TYR n 
1 1203 LEU n 
1 1204 SER n 
1 1205 LYS n 
1 1206 ALA n 
1 1207 ALA n 
1 1208 ALA n 
1 1209 THR n 
1 1210 TYR n 
1 1211 VAL n 
1 1212 GLN n 
1 1213 GLU n 
1 1214 PHE n 
1 1215 LEU n 
1 1216 PRO n 
1 1217 HIS n 
1 1218 SEP n 
1 1219 ILE n 
1 1220 CYS n 
1 1221 ALA n 
1 1222 MET n 
1 1223 GLN n 
2 1    MET n 
2 2    THR n 
2 3    ARG n 
2 4    ASP n 
2 5    GLU n 
2 6    ALA n 
2 7    LEU n 
2 8    PRO n 
2 9    ASP n 
2 10   SER n 
2 11   HIS n 
2 12   SER n 
2 13   ALA n 
2 14   GLN n 
2 15   ASP n 
2 16   PHE n 
2 17   TYR n 
2 18   GLU n 
2 19   ASN n 
2 20   TYR n 
2 21   GLU n 
2 22   PRO n 
2 23   LYS n 
2 24   GLU n 
2 25   ILE n 
2 26   LEU n 
2 27   GLY n 
2 28   ARG n 
2 29   GLY n 
2 30   VAL n 
2 31   SER n 
2 32   SER n 
2 33   VAL n 
2 34   VAL n 
2 35   ARG n 
2 36   ARG n 
2 37   CYS n 
2 38   ILE n 
2 39   HIS n 
2 40   LYS n 
2 41   PRO n 
2 42   THR n 
2 43   SER n 
2 44   GLN n 
2 45   GLU n 
2 46   TYR n 
2 47   ALA n 
2 48   VAL n 
2 49   LYS n 
2 50   VAL n 
2 51   ILE n 
2 52   ASP n 
2 53   VAL n 
2 54   THR n 
2 55   GLY n 
2 56   GLY n 
2 57   GLY n 
2 58   SER n 
2 59   PHE n 
2 60   SER n 
2 61   PRO n 
2 62   GLU n 
2 63   GLU n 
2 64   VAL n 
2 65   ARG n 
2 66   GLU n 
2 67   LEU n 
2 68   ARG n 
2 69   GLU n 
2 70   ALA n 
2 71   THR n 
2 72   LEU n 
2 73   LYS n 
2 74   GLU n 
2 75   VAL n 
2 76   ASP n 
2 77   ILE n 
2 78   LEU n 
2 79   ARG n 
2 80   LYS n 
2 81   VAL n 
2 82   SER n 
2 83   GLY n 
2 84   HIS n 
2 85   PRO n 
2 86   ASN n 
2 87   ILE n 
2 88   ILE n 
2 89   GLN n 
2 90   LEU n 
2 91   LYS n 
2 92   ASP n 
2 93   THR n 
2 94   TYR n 
2 95   GLU n 
2 96   THR n 
2 97   ASN n 
2 98   THR n 
2 99   PHE n 
2 100  PHE n 
2 101  PHE n 
2 102  LEU n 
2 103  VAL n 
2 104  PHE n 
2 105  ASP n 
2 106  LEU n 
2 107  MET n 
2 108  LYS n 
2 109  ARG n 
2 110  GLY n 
2 111  GLU n 
2 112  LEU n 
2 113  PHE n 
2 114  ASP n 
2 115  TYR n 
2 116  LEU n 
2 117  THR n 
2 118  GLU n 
2 119  LYS n 
2 120  VAL n 
2 121  THR n 
2 122  LEU n 
2 123  SER n 
2 124  GLU n 
2 125  LYS n 
2 126  GLU n 
2 127  THR n 
2 128  ARG n 
2 129  LYS n 
2 130  ILE n 
2 131  MET n 
2 132  ARG n 
2 133  ALA n 
2 134  LEU n 
2 135  LEU n 
2 136  GLU n 
2 137  VAL n 
2 138  ILE n 
2 139  CYS n 
2 140  THR n 
2 141  LEU n 
2 142  HIS n 
2 143  LYS n 
2 144  LEU n 
2 145  ASN n 
2 146  ILE n 
2 147  VAL n 
2 148  HIS n 
2 149  ARG n 
2 150  ASP n 
2 151  LEU n 
2 152  LYS n 
2 153  PRO n 
2 154  GLU n 
2 155  ASN n 
2 156  ILE n 
2 157  LEU n 
2 158  LEU n 
2 159  ASP n 
2 160  ASP n 
2 161  ASN n 
2 162  MET n 
2 163  ASN n 
2 164  ILE n 
2 165  LYS n 
2 166  LEU n 
2 167  THR n 
2 168  ASP n 
2 169  PHE n 
2 170  GLY n 
2 171  PHE n 
2 172  SER n 
2 173  CYS n 
2 174  GLN n 
2 175  LEU n 
2 176  GLU n 
2 177  PRO n 
2 178  GLY n 
2 179  GLU n 
2 180  ARG n 
2 181  LEU n 
2 182  ARG n 
2 183  GLU n 
2 184  VAL n 
2 185  CYS n 
2 186  GLY n 
2 187  THR n 
2 188  PRO n 
2 189  SER n 
2 190  TYR n 
2 191  LEU n 
2 192  ALA n 
2 193  PRO n 
2 194  GLU n 
2 195  ILE n 
2 196  ILE n 
2 197  GLU n 
2 198  CYS n 
2 199  SER n 
2 200  MET n 
2 201  ASN n 
2 202  GLU n 
2 203  ASP n 
2 204  HIS n 
2 205  PRO n 
2 206  GLY n 
2 207  TYR n 
2 208  GLY n 
2 209  LYS n 
2 210  GLU n 
2 211  VAL n 
2 212  ASP n 
2 213  MET n 
2 214  TRP n 
2 215  SER n 
2 216  THR n 
2 217  GLY n 
2 218  VAL n 
2 219  ILE n 
2 220  MET n 
2 221  TYR n 
2 222  THR n 
2 223  LEU n 
2 224  LEU n 
2 225  ALA n 
2 226  GLY n 
2 227  SER n 
2 228  PRO n 
2 229  PRO n 
2 230  PHE n 
2 231  TRP n 
2 232  HIS n 
2 233  ARG n 
2 234  LYS n 
2 235  GLN n 
2 236  MET n 
2 237  LEU n 
2 238  MET n 
2 239  LEU n 
2 240  ARG n 
2 241  MET n 
2 242  ILE n 
2 243  MET n 
2 244  SER n 
2 245  GLY n 
2 246  ASN n 
2 247  TYR n 
2 248  GLN n 
2 249  PHE n 
2 250  GLY n 
2 251  SER n 
2 252  PRO n 
2 253  GLU n 
2 254  TRP n 
2 255  ASP n 
2 256  ASP n 
2 257  TYR n 
2 258  SER n 
2 259  ASP n 
2 260  THR n 
2 261  VAL n 
2 262  LYS n 
2 263  ASP n 
2 264  LEU n 
2 265  VAL n 
2 266  SER n 
2 267  ARG n 
2 268  PHE n 
2 269  LEU n 
2 270  VAL n 
2 271  VAL n 
2 272  GLN n 
2 273  PRO n 
2 274  GLN n 
2 275  ASN n 
2 276  ARG n 
2 277  TYR n 
2 278  THR n 
2 279  ALA n 
2 280  GLU n 
2 281  GLU n 
2 282  ALA n 
2 283  LEU n 
2 284  ALA n 
2 285  HIS n 
2 286  PRO n 
2 287  PHE n 
2 288  PHE n 
2 289  GLN n 
2 290  GLN n 
2 291  TYR n 
2 292  LEU n 
2 293  VAL n 
2 294  GLU n 
2 295  GLU n 
2 296  VAL n 
2 297  ARG n 
2 298  HIS n 
2 299  PHE n 
2 300  SER n 
2 301  PRO n 
2 302  ARG n 
2 303  GLY n 
2 304  LYS n 
2 305  PHE n 
2 306  LYS n 
2 307  VAL n 
2 308  ILE n 
2 309  ALA n 
2 310  LEU n 
2 311  THR n 
2 312  VAL n 
2 313  LEU n 
2 314  ALA n 
2 315  SER n 
2 316  VAL n 
2 317  ARG n 
2 318  ILE n 
2 319  TYR n 
2 320  TYR n 
2 321  GLN n 
2 322  TYR n 
2 323  ARG n 
2 324  ARG n 
2 325  VAL n 
2 326  LYS n 
2 327  PRO n 
2 328  VAL n 
2 329  THR n 
2 330  ARG n 
2 331  GLU n 
2 332  ILE n 
2 333  VAL n 
2 334  ILE n 
2 335  ARG n 
2 336  ASP n 
2 337  PRO n 
2 338  TYR n 
2 339  ALA n 
2 340  LEU n 
2 341  ARG n 
2 342  PRO n 
2 343  LEU n 
2 344  ARG n 
2 345  ARG n 
2 346  LEU n 
2 347  ILE n 
2 348  ASP n 
2 349  ALA n 
2 350  TYR n 
2 351  ALA n 
2 352  PHE n 
2 353  ARG n 
2 354  ILE n 
2 355  TYR n 
2 356  GLY n 
2 357  HIS n 
2 358  TRP n 
2 359  VAL n 
2 360  LYS n 
2 361  LYS n 
2 362  GLY n 
2 363  GLN n 
2 364  GLN n 
2 365  GLN n 
2 366  ASN n 
2 367  ARG n 
2 368  ALA n 
2 369  ALA n 
2 370  LEU n 
2 371  PHE n 
2 372  GLU n 
2 373  ASN n 
2 374  THR n 
2 375  PRO n 
2 376  LYS n 
2 377  ALA n 
2 378  VAL n 
2 379  LEU n 
2 380  LEU n 
2 381  SER n 
2 382  LEU n 
2 383  ALA n 
2 384  GLU n 
2 385  GLU n 
2 386  ASP n 
2 387  TYR n 
3 1    ASP n 
3 2    TYR n 
3 3    LYS n 
3 4    ASP n 
3 5    ASP n 
3 6    ASP n 
3 7    ASP n 
3 8    LYS n 
3 9    SER n 
3 10   GLY n 
3 11   PRO n 
3 12   ASP n 
3 13   GLU n 
3 14   VAL n 
3 15   ASP n 
3 16   ALA n 
3 17   SER n 
3 18   GLY n 
3 19   ARG n 
3 20   MET n 
3 21   ALA n 
3 22   ASP n 
3 23   GLN n 
3 24   LEU n 
3 25   THR n 
3 26   GLU n 
3 27   GLU n 
3 28   GLN n 
3 29   ILE n 
3 30   ALA n 
3 31   GLU n 
3 32   PHE n 
3 33   LYS n 
3 34   GLU n 
3 35   ALA n 
3 36   PHE n 
3 37   SER n 
3 38   LEU n 
3 39   PHE n 
3 40   ASP n 
3 41   LYS n 
3 42   ASP n 
3 43   GLY n 
3 44   ASP n 
3 45   GLY n 
3 46   THR n 
3 47   ILE n 
3 48   THR n 
3 49   THR n 
3 50   LYS n 
3 51   GLU n 
3 52   LEU n 
3 53   GLY n 
3 54   THR n 
3 55   VAL n 
3 56   MET n 
3 57   ARG n 
3 58   SER n 
3 59   LEU n 
3 60   GLY n 
3 61   GLN n 
3 62   ASN n 
3 63   PRO n 
3 64   THR n 
3 65   GLU n 
3 66   ALA n 
3 67   GLU n 
3 68   LEU n 
3 69   GLN n 
3 70   ASP n 
3 71   MET n 
3 72   ILE n 
3 73   ASN n 
3 74   GLU n 
3 75   VAL n 
3 76   ASP n 
3 77   ALA n 
3 78   ASP n 
3 79   GLY n 
3 80   ASN n 
3 81   GLY n 
3 82   THR n 
3 83   ILE n 
3 84   ASP n 
3 85   PHE n 
3 86   PRO n 
3 87   GLU n 
3 88   PHE n 
3 89   LEU n 
3 90   THR n 
3 91   MET n 
3 92   MET n 
3 93   ALA n 
3 94   ARG n 
3 95   LYS n 
3 96   MET n 
3 97   LYS n 
3 98   ASP n 
3 99   THR n 
3 100  ASP n 
3 101  SER n 
3 102  GLU n 
3 103  GLU n 
3 104  GLU n 
3 105  ILE n 
3 106  ARG n 
3 107  GLU n 
3 108  ALA n 
3 109  PHE n 
3 110  ARG n 
3 111  VAL n 
3 112  PHE n 
3 113  ASP n 
3 114  LYS n 
3 115  ASP n 
3 116  GLY n 
3 117  ASN n 
3 118  GLY n 
3 119  TYR n 
3 120  ILE n 
3 121  SER n 
3 122  ALA n 
3 123  ALA n 
3 124  GLU n 
3 125  LEU n 
3 126  ARG n 
3 127  HIS n 
3 128  VAL n 
3 129  MET n 
3 130  THR n 
3 131  ASN n 
3 132  LEU n 
3 133  GLY n 
3 134  GLU n 
3 135  LYS n 
3 136  LEU n 
3 137  THR n 
3 138  ASP n 
3 139  GLU n 
3 140  GLU n 
3 141  VAL n 
3 142  ASP n 
3 143  GLU n 
3 144  MET n 
3 145  ILE n 
3 146  ARG n 
3 147  GLU n 
3 148  ALA n 
3 149  ASP n 
3 150  ILE n 
3 151  ASP n 
3 152  GLY n 
3 153  ASP n 
3 154  GLY n 
3 155  GLN n 
3 156  VAL n 
3 157  ASN n 
3 158  TYR n 
3 159  GLU n 
3 160  GLU n 
3 161  PHE n 
3 162  VAL n 
3 163  GLN n 
3 164  MET n 
3 165  MET n 
3 166  THR n 
3 167  ALA n 
3 168  LYS n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 1223 human ? 'PHKA1, PHKA'                       ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? 
? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 387  human ? 'PHKG1, PHKG'                       ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? 
? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
3 1 sample 'Biological sequence' 1 168  human ? 'CALM3, CALML2, CAM3, CAMC, CAMIII' ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? 
? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                     ?                  'C3 H7 N O2'        89.093  
ARG 'L-peptide linking' y ARGININE                    ?                  'C6 H15 N4 O2 1'    175.209 
ASN 'L-peptide linking' y ASPARAGINE                  ?                  'C4 H8 N2 O3'       132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'             ?                  'C4 H7 N O4'        133.103 
ATP non-polymer         . "ADENOSINE-5'-TRIPHOSPHATE" ?                  'C10 H16 N5 O13 P3' 507.181 
CYS 'L-peptide linking' y CYSTEINE                    ?                  'C3 H7 N O2 S'      121.158 
GLN 'L-peptide linking' y GLUTAMINE                   ?                  'C5 H10 N2 O3'      146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'             ?                  'C5 H9 N O4'        147.129 
GLY 'peptide linking'   y GLYCINE                     ?                  'C2 H5 N O2'        75.067  
HIS 'L-peptide linking' y HISTIDINE                   ?                  'C6 H10 N3 O2 1'    156.162 
ILE 'L-peptide linking' y ISOLEUCINE                  ?                  'C6 H13 N O2'       131.173 
LEU 'L-peptide linking' y LEUCINE                     ?                  'C6 H13 N O2'       131.173 
LYS 'L-peptide linking' y LYSINE                      ?                  'C6 H15 N2 O2 1'    147.195 
MET 'L-peptide linking' y METHIONINE                  ?                  'C5 H11 N O2 S'     149.211 
PHE 'L-peptide linking' y PHENYLALANINE               ?                  'C9 H11 N O2'       165.189 
PRO 'L-peptide linking' y PROLINE                     ?                  'C5 H9 N O2'        115.130 
SEP 'L-peptide linking' n PHOSPHOSERINE               PHOSPHONOSERINE    'C3 H8 N O6 P'      185.072 
SER 'L-peptide linking' y SERINE                      ?                  'C3 H7 N O3'        105.093 
THR 'L-peptide linking' y THREONINE                   ?                  'C4 H9 N O3'        119.119 
TPO 'L-peptide linking' n PHOSPHOTHREONINE            PHOSPHONOTHREONINE 'C4 H10 N O6 P'     199.099 
TRP 'L-peptide linking' y TRYPTOPHAN                  ?                  'C11 H12 N2 O2'     204.225 
TYR 'L-peptide linking' y TYROSINE                    ?                  'C9 H11 N O3'       181.189 
VAL 'L-peptide linking' y VALINE                      ?                  'C5 H11 N O2'       117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1    MET 1    1    ?    ?   ?   A . n 
A 1 2    ARG 2    2    ?    ?   ?   A . n 
A 1 3    SER 3    3    ?    ?   ?   A . n 
A 1 4    ARG 4    4    ?    ?   ?   A . n 
A 1 5    SER 5    5    5    SER SER A . n 
A 1 6    ASN 6    6    6    ASN ASN A . n 
A 1 7    SER 7    7    7    SER SER A . n 
A 1 8    GLY 8    8    8    GLY GLY A . n 
A 1 9    VAL 9    9    9    VAL VAL A . n 
A 1 10   ARG 10   10   10   ARG ARG A . n 
A 1 11   LEU 11   11   11   LEU LEU A . n 
A 1 12   ASP 12   12   12   ASP ASP A . n 
A 1 13   GLY 13   13   13   GLY GLY A . n 
A 1 14   TYR 14   14   14   TYR TYR A . n 
A 1 15   ALA 15   15   15   ALA ALA A . n 
A 1 16   ARG 16   16   16   ARG ARG A . n 
A 1 17   LEU 17   17   17   LEU LEU A . n 
A 1 18   VAL 18   18   18   VAL VAL A . n 
A 1 19   GLN 19   19   19   GLN GLN A . n 
A 1 20   GLN 20   20   20   GLN GLN A . n 
A 1 21   THR 21   21   21   THR THR A . n 
A 1 22   ILE 22   22   22   ILE ILE A . n 
A 1 23   LEU 23   23   23   LEU LEU A . n 
A 1 24   CYS 24   24   24   CYS CYS A . n 
A 1 25   HIS 25   25   25   HIS HIS A . n 
A 1 26   GLN 26   26   26   GLN GLN A . n 
A 1 27   ASN 27   27   27   ASN ASN A . n 
A 1 28   PRO 28   28   28   PRO PRO A . n 
A 1 29   VAL 29   29   29   VAL VAL A . n 
A 1 30   THR 30   30   30   THR THR A . n 
A 1 31   GLY 31   31   31   GLY GLY A . n 
A 1 32   LEU 32   32   32   LEU LEU A . n 
A 1 33   LEU 33   33   33   LEU LEU A . n 
A 1 34   PRO 34   34   34   PRO PRO A . n 
A 1 35   ALA 35   35   35   ALA ALA A . n 
A 1 36   SER 36   36   36   SER SER A . n 
A 1 37   TYR 37   37   37   TYR TYR A . n 
A 1 38   ASP 38   38   38   ASP ASP A . n 
A 1 39   GLN 39   39   39   GLN GLN A . n 
A 1 40   LYS 40   40   40   LYS LYS A . n 
A 1 41   ASP 41   41   41   ASP ASP A . n 
A 1 42   ALA 42   42   42   ALA ALA A . n 
A 1 43   TRP 43   43   43   TRP TRP A . n 
A 1 44   VAL 44   44   44   VAL VAL A . n 
A 1 45   ARG 45   45   45   ARG ARG A . n 
A 1 46   ASP 46   46   46   ASP ASP A . n 
A 1 47   ASN 47   47   47   ASN ASN A . n 
A 1 48   VAL 48   48   48   VAL VAL A . n 
A 1 49   TYR 49   49   49   TYR TYR A . n 
A 1 50   SER 50   50   50   SER SER A . n 
A 1 51   ILE 51   51   51   ILE ILE A . n 
A 1 52   LEU 52   52   52   LEU LEU A . n 
A 1 53   ALA 53   53   53   ALA ALA A . n 
A 1 54   VAL 54   54   54   VAL VAL A . n 
A 1 55   TRP 55   55   55   TRP TRP A . n 
A 1 56   GLY 56   56   56   GLY GLY A . n 
A 1 57   LEU 57   57   57   LEU LEU A . n 
A 1 58   GLY 58   58   58   GLY GLY A . n 
A 1 59   LEU 59   59   59   LEU LEU A . n 
A 1 60   ALA 60   60   60   ALA ALA A . n 
A 1 61   TYR 61   61   61   TYR TYR A . n 
A 1 62   ARG 62   62   62   ARG ARG A . n 
A 1 63   LYS 63   63   63   LYS LYS A . n 
A 1 64   ASN 64   64   64   ASN ASN A . n 
A 1 65   ALA 65   65   65   ALA ALA A . n 
A 1 66   ASP 66   66   66   ASP ASP A . n 
A 1 67   ARG 67   67   67   ARG ARG A . n 
A 1 68   ASP 68   68   68   ASP ASP A . n 
A 1 69   GLU 69   69   69   GLU GLU A . n 
A 1 70   ASP 70   70   70   ASP ASP A . n 
A 1 71   LYS 71   71   71   LYS LYS A . n 
A 1 72   ALA 72   72   72   ALA ALA A . n 
A 1 73   LYS 73   73   73   LYS LYS A . n 
A 1 74   ALA 74   74   74   ALA ALA A . n 
A 1 75   TYR 75   75   75   TYR TYR A . n 
A 1 76   GLU 76   76   76   GLU GLU A . n 
A 1 77   LEU 77   77   77   LEU LEU A . n 
A 1 78   GLU 78   78   78   GLU GLU A . n 
A 1 79   GLN 79   79   79   GLN GLN A . n 
A 1 80   SER 80   80   80   SER SER A . n 
A 1 81   VAL 81   81   81   VAL VAL A . n 
A 1 82   VAL 82   82   82   VAL VAL A . n 
A 1 83   LYS 83   83   83   LYS LYS A . n 
A 1 84   LEU 84   84   84   LEU LEU A . n 
A 1 85   MET 85   85   85   MET MET A . n 
A 1 86   ARG 86   86   86   ARG ARG A . n 
A 1 87   GLY 87   87   87   GLY GLY A . n 
A 1 88   LEU 88   88   88   LEU LEU A . n 
A 1 89   LEU 89   89   89   LEU LEU A . n 
A 1 90   HIS 90   90   90   HIS HIS A . n 
A 1 91   CYS 91   91   91   CYS CYS A . n 
A 1 92   MET 92   92   92   MET MET A . n 
A 1 93   ILE 93   93   93   ILE ILE A . n 
A 1 94   ARG 94   94   94   ARG ARG A . n 
A 1 95   GLN 95   95   95   GLN GLN A . n 
A 1 96   VAL 96   96   96   VAL VAL A . n 
A 1 97   ASP 97   97   97   ASP ASP A . n 
A 1 98   LYS 98   98   98   LYS LYS A . n 
A 1 99   VAL 99   99   99   VAL VAL A . n 
A 1 100  GLU 100  100  100  GLU GLU A . n 
A 1 101  SEP 101  101  101  SEP SEP A . n 
A 1 102  PHE 102  102  102  PHE PHE A . n 
A 1 103  LYS 103  103  103  LYS LYS A . n 
A 1 104  TYR 104  104  104  TYR TYR A . n 
A 1 105  SEP 105  105  105  SEP SEP A . n 
A 1 106  GLN 106  106  106  GLN GLN A . n 
A 1 107  SEP 107  107  107  SEP SEP A . n 
A 1 108  THR 108  108  108  THR THR A . n 
A 1 109  LYS 109  109  109  LYS LYS A . n 
A 1 110  ASP 110  110  110  ASP ASP A . n 
A 1 111  SEP 111  111  111  SEP SEP A . n 
A 1 112  LEU 112  112  112  LEU LEU A . n 
A 1 113  HIS 113  113  113  HIS HIS A . n 
A 1 114  ALA 114  114  114  ALA ALA A . n 
A 1 115  LYS 115  115  115  LYS LYS A . n 
A 1 116  TYR 116  116  116  TYR TYR A . n 
A 1 117  ASN 117  117  117  ASN ASN A . n 
A 1 118  THR 118  118  118  THR THR A . n 
A 1 119  LYS 119  119  119  LYS LYS A . n 
A 1 120  THR 120  120  120  THR THR A . n 
A 1 121  CYS 121  121  121  CYS CYS A . n 
A 1 122  ALA 122  122  122  ALA ALA A . n 
A 1 123  THR 123  123  123  THR THR A . n 
A 1 124  VAL 124  124  124  VAL VAL A . n 
A 1 125  VAL 125  125  125  VAL VAL A . n 
A 1 126  GLY 126  126  126  GLY GLY A . n 
A 1 127  ASP 127  127  127  ASP ASP A . n 
A 1 128  ASP 128  128  128  ASP ASP A . n 
A 1 129  GLN 129  129  129  GLN GLN A . n 
A 1 130  TRP 130  130  130  TRP TRP A . n 
A 1 131  GLY 131  131  131  GLY GLY A . n 
A 1 132  HIS 132  132  132  HIS HIS A . n 
A 1 133  LEU 133  133  133  LEU LEU A . n 
A 1 134  GLN 134  134  134  GLN GLN A . n 
A 1 135  LEU 135  135  135  LEU LEU A . n 
A 1 136  ASP 136  136  136  ASP ASP A . n 
A 1 137  ALA 137  137  137  ALA ALA A . n 
A 1 138  THR 138  138  138  THR THR A . n 
A 1 139  SER 139  139  139  SER SER A . n 
A 1 140  VAL 140  140  140  VAL VAL A . n 
A 1 141  TYR 141  141  141  TYR TYR A . n 
A 1 142  LEU 142  142  142  LEU LEU A . n 
A 1 143  LEU 143  143  143  LEU LEU A . n 
A 1 144  PHE 144  144  144  PHE PHE A . n 
A 1 145  LEU 145  145  145  LEU LEU A . n 
A 1 146  ALA 146  146  146  ALA ALA A . n 
A 1 147  GLN 147  147  147  GLN GLN A . n 
A 1 148  MET 148  148  148  MET MET A . n 
A 1 149  THR 149  149  149  THR THR A . n 
A 1 150  ALA 150  150  150  ALA ALA A . n 
A 1 151  SER 151  151  151  SER SER A . n 
A 1 152  GLY 152  152  152  GLY GLY A . n 
A 1 153  LEU 153  153  153  LEU LEU A . n 
A 1 154  HIS 154  154  154  HIS HIS A . n 
A 1 155  ILE 155  155  155  ILE ILE A . n 
A 1 156  ILE 156  156  156  ILE ILE A . n 
A 1 157  HIS 157  157  157  HIS HIS A . n 
A 1 158  SER 158  158  158  SER SER A . n 
A 1 159  LEU 159  159  159  LEU LEU A . n 
A 1 160  ASP 160  160  160  ASP ASP A . n 
A 1 161  GLU 161  161  161  GLU GLU A . n 
A 1 162  VAL 162  162  162  VAL VAL A . n 
A 1 163  ASN 163  163  163  ASN ASN A . n 
A 1 164  PHE 164  164  164  PHE PHE A . n 
A 1 165  ILE 165  165  165  ILE ILE A . n 
A 1 166  GLN 166  166  166  GLN GLN A . n 
A 1 167  ASN 167  167  167  ASN ASN A . n 
A 1 168  LEU 168  168  168  LEU LEU A . n 
A 1 169  VAL 169  169  169  VAL VAL A . n 
A 1 170  PHE 170  170  170  PHE PHE A . n 
A 1 171  TYR 171  171  171  TYR TYR A . n 
A 1 172  ILE 172  172  172  ILE ILE A . n 
A 1 173  GLU 173  173  173  GLU GLU A . n 
A 1 174  ALA 174  174  174  ALA ALA A . n 
A 1 175  ALA 175  175  175  ALA ALA A . n 
A 1 176  TYR 176  176  176  TYR TYR A . n 
A 1 177  LYS 177  177  177  LYS LYS A . n 
A 1 178  THR 178  178  178  THR THR A . n 
A 1 179  ALA 179  179  179  ALA ALA A . n 
A 1 180  ASP 180  180  180  ASP ASP A . n 
A 1 181  PHE 181  181  181  PHE PHE A . n 
A 1 182  GLY 182  182  182  GLY GLY A . n 
A 1 183  ILE 183  183  183  ILE ILE A . n 
A 1 184  TRP 184  184  184  TRP TRP A . n 
A 1 185  GLU 185  185  185  GLU GLU A . n 
A 1 186  ARG 186  186  186  ARG ARG A . n 
A 1 187  GLY 187  187  187  GLY GLY A . n 
A 1 188  ASP 188  188  188  ASP ASP A . n 
A 1 189  LYS 189  189  189  LYS LYS A . n 
A 1 190  THR 190  190  190  THR THR A . n 
A 1 191  ASN 191  191  191  ASN ASN A . n 
A 1 192  GLN 192  192  192  GLN GLN A . n 
A 1 193  GLY 193  193  193  GLY GLY A . n 
A 1 194  ILE 194  194  194  ILE ILE A . n 
A 1 195  SER 195  195  195  SER SER A . n 
A 1 196  GLU 196  196  196  GLU GLU A . n 
A 1 197  LEU 197  197  197  LEU LEU A . n 
A 1 198  ASN 198  198  198  ASN ASN A . n 
A 1 199  ALA 199  199  199  ALA ALA A . n 
A 1 200  SER 200  200  200  SER SER A . n 
A 1 201  SEP 201  201  201  SEP SEP A . n 
A 1 202  VAL 202  202  202  VAL VAL A . n 
A 1 203  GLY 203  203  203  GLY GLY A . n 
A 1 204  MET 204  204  204  MET MET A . n 
A 1 205  ALA 205  205  205  ALA ALA A . n 
A 1 206  LYS 206  206  206  LYS LYS A . n 
A 1 207  ALA 207  207  207  ALA ALA A . n 
A 1 208  ALA 208  208  208  ALA ALA A . n 
A 1 209  LEU 209  209  209  LEU LEU A . n 
A 1 210  GLU 210  210  210  GLU GLU A . n 
A 1 211  ALA 211  211  211  ALA ALA A . n 
A 1 212  LEU 212  212  212  LEU LEU A . n 
A 1 213  ASP 213  213  213  ASP ASP A . n 
A 1 214  GLU 214  214  214  GLU GLU A . n 
A 1 215  LEU 215  215  215  LEU LEU A . n 
A 1 216  ASP 216  216  216  ASP ASP A . n 
A 1 217  LEU 217  217  217  LEU LEU A . n 
A 1 218  PHE 218  218  218  PHE PHE A . n 
A 1 219  GLY 219  219  219  GLY GLY A . n 
A 1 220  VAL 220  220  220  VAL VAL A . n 
A 1 221  LYS 221  221  221  LYS LYS A . n 
A 1 222  GLY 222  222  222  GLY GLY A . n 
A 1 223  GLY 223  223  223  GLY GLY A . n 
A 1 224  PRO 224  224  224  PRO PRO A . n 
A 1 225  GLN 225  225  225  GLN GLN A . n 
A 1 226  SER 226  226  226  SER SER A . n 
A 1 227  VAL 227  227  227  VAL VAL A . n 
A 1 228  ILE 228  228  228  ILE ILE A . n 
A 1 229  HIS 229  229  229  HIS HIS A . n 
A 1 230  VAL 230  230  230  VAL VAL A . n 
A 1 231  LEU 231  231  231  LEU LEU A . n 
A 1 232  ALA 232  232  232  ALA ALA A . n 
A 1 233  ASP 233  233  233  ASP ASP A . n 
A 1 234  GLU 234  234  234  GLU GLU A . n 
A 1 235  VAL 235  235  235  VAL VAL A . n 
A 1 236  GLN 236  236  236  GLN GLN A . n 
A 1 237  HIS 237  237  237  HIS HIS A . n 
A 1 238  CYS 238  238  238  CYS CYS A . n 
A 1 239  GLN 239  239  239  GLN GLN A . n 
A 1 240  SEP 240  240  240  SEP SEP A . n 
A 1 241  ILE 241  241  241  ILE ILE A . n 
A 1 242  LEU 242  242  242  LEU LEU A . n 
A 1 243  ASN 243  243  243  ASN ASN A . n 
A 1 244  SER 244  244  244  SER SER A . n 
A 1 245  LEU 245  245  245  LEU LEU A . n 
A 1 246  LEU 246  246  246  LEU LEU A . n 
A 1 247  PRO 247  247  247  PRO PRO A . n 
A 1 248  ARG 248  248  248  ARG ARG A . n 
A 1 249  ALA 249  249  249  ALA ALA A . n 
A 1 250  SER 250  250  250  SER SER A . n 
A 1 251  THR 251  251  251  THR THR A . n 
A 1 252  SER 252  252  252  SER SER A . n 
A 1 253  LYS 253  253  253  LYS LYS A . n 
A 1 254  GLU 254  254  254  GLU GLU A . n 
A 1 255  VAL 255  255  255  VAL VAL A . n 
A 1 256  ASP 256  256  256  ASP ASP A . n 
A 1 257  ALA 257  257  257  ALA ALA A . n 
A 1 258  SER 258  258  258  SER SER A . n 
A 1 259  LEU 259  259  259  LEU LEU A . n 
A 1 260  LEU 260  260  260  LEU LEU A . n 
A 1 261  SER 261  261  261  SER SER A . n 
A 1 262  VAL 262  262  262  VAL VAL A . n 
A 1 263  VAL 263  263  263  VAL VAL A . n 
A 1 264  SER 264  264  264  SER SER A . n 
A 1 265  PHE 265  265  265  PHE PHE A . n 
A 1 266  PRO 266  266  266  PRO PRO A . n 
A 1 267  ALA 267  267  267  ALA ALA A . n 
A 1 268  PHE 268  268  268  PHE PHE A . n 
A 1 269  ALA 269  269  269  ALA ALA A . n 
A 1 270  VAL 270  270  270  VAL VAL A . n 
A 1 271  GLU 271  271  271  GLU GLU A . n 
A 1 272  ASP 272  272  272  ASP ASP A . n 
A 1 273  SER 273  273  273  SER SER A . n 
A 1 274  GLN 274  274  274  GLN GLN A . n 
A 1 275  LEU 275  275  275  LEU LEU A . n 
A 1 276  VAL 276  276  276  VAL VAL A . n 
A 1 277  GLU 277  277  277  GLU GLU A . n 
A 1 278  LEU 278  278  278  LEU LEU A . n 
A 1 279  THR 279  279  279  THR THR A . n 
A 1 280  LYS 280  280  280  LYS LYS A . n 
A 1 281  GLN 281  281  281  GLN GLN A . n 
A 1 282  GLU 282  282  282  GLU GLU A . n 
A 1 283  ILE 283  283  283  ILE ILE A . n 
A 1 284  ILE 284  284  284  ILE ILE A . n 
A 1 285  THR 285  285  285  THR THR A . n 
A 1 286  LYS 286  286  286  LYS LYS A . n 
A 1 287  LEU 287  287  287  LEU LEU A . n 
A 1 288  GLN 288  288  288  GLN GLN A . n 
A 1 289  GLY 289  289  289  GLY GLY A . n 
A 1 290  ARG 290  290  290  ARG ARG A . n 
A 1 291  TYR 291  291  291  TYR TYR A . n 
A 1 292  GLY 292  292  292  GLY GLY A . n 
A 1 293  CYS 293  293  293  CYS CYS A . n 
A 1 294  CYS 294  294  294  CYS CYS A . n 
A 1 295  ARG 295  295  295  ARG ARG A . n 
A 1 296  PHE 296  296  296  PHE PHE A . n 
A 1 297  LEU 297  297  297  LEU LEU A . n 
A 1 298  ARG 298  298  298  ARG ARG A . n 
A 1 299  ASP 299  299  299  ASP ASP A . n 
A 1 300  GLY 300  300  300  GLY GLY A . n 
A 1 301  TYR 301  301  301  TYR TYR A . n 
A 1 302  LYS 302  302  302  LYS LYS A . n 
A 1 303  THR 303  303  303  THR THR A . n 
A 1 304  PRO 304  304  304  PRO PRO A . n 
A 1 305  LYS 305  305  305  LYS LYS A . n 
A 1 306  GLU 306  306  306  GLU GLU A . n 
A 1 307  ASP 307  307  307  ASP ASP A . n 
A 1 308  PRO 308  308  308  PRO PRO A . n 
A 1 309  ASN 309  309  309  ASN ASN A . n 
A 1 310  ARG 310  310  310  ARG ARG A . n 
A 1 311  LEU 311  311  311  LEU LEU A . n 
A 1 312  TYR 312  312  312  TYR TYR A . n 
A 1 313  TYR 313  313  313  TYR TYR A . n 
A 1 314  GLU 314  314  314  GLU GLU A . n 
A 1 315  PRO 315  315  315  PRO PRO A . n 
A 1 316  ALA 316  316  316  ALA ALA A . n 
A 1 317  GLU 317  317  317  GLU GLU A . n 
A 1 318  LEU 318  318  318  LEU LEU A . n 
A 1 319  LYS 319  319  319  LYS LYS A . n 
A 1 320  LEU 320  320  320  LEU LEU A . n 
A 1 321  PHE 321  321  321  PHE PHE A . n 
A 1 322  GLU 322  322  322  GLU GLU A . n 
A 1 323  ASN 323  323  323  ASN ASN A . n 
A 1 324  ILE 324  324  324  ILE ILE A . n 
A 1 325  GLU 325  325  325  GLU GLU A . n 
A 1 326  CYS 326  326  326  CYS CYS A . n 
A 1 327  GLU 327  327  327  GLU GLU A . n 
A 1 328  TRP 328  328  328  TRP TRP A . n 
A 1 329  PRO 329  329  329  PRO PRO A . n 
A 1 330  LEU 330  330  330  LEU LEU A . n 
A 1 331  PHE 331  331  331  PHE PHE A . n 
A 1 332  TRP 332  332  332  TRP TRP A . n 
A 1 333  THR 333  333  333  THR THR A . n 
A 1 334  TYR 334  334  334  TYR TYR A . n 
A 1 335  PHE 335  335  335  PHE PHE A . n 
A 1 336  ILE 336  336  336  ILE ILE A . n 
A 1 337  LEU 337  337  337  LEU LEU A . n 
A 1 338  ASP 338  338  338  ASP ASP A . n 
A 1 339  GLY 339  339  339  GLY GLY A . n 
A 1 340  VAL 340  340  340  VAL VAL A . n 
A 1 341  PHE 341  341  341  PHE PHE A . n 
A 1 342  SER 342  342  342  SER SER A . n 
A 1 343  GLY 343  343  343  GLY GLY A . n 
A 1 344  ASN 344  344  344  ASN ASN A . n 
A 1 345  ALA 345  345  345  ALA ALA A . n 
A 1 346  GLU 346  346  346  GLU GLU A . n 
A 1 347  GLN 347  347  347  GLN GLN A . n 
A 1 348  VAL 348  348  348  VAL VAL A . n 
A 1 349  GLN 349  349  349  GLN GLN A . n 
A 1 350  GLU 350  350  350  GLU GLU A . n 
A 1 351  TYR 351  351  351  TYR TYR A . n 
A 1 352  LYS 352  352  352  LYS LYS A . n 
A 1 353  GLU 353  353  353  GLU GLU A . n 
A 1 354  ALA 354  354  354  ALA ALA A . n 
A 1 355  LEU 355  355  355  LEU LEU A . n 
A 1 356  GLU 356  356  356  GLU GLU A . n 
A 1 357  ALA 357  357  357  ALA ALA A . n 
A 1 358  VAL 358  358  358  VAL VAL A . n 
A 1 359  LEU 359  359  359  LEU LEU A . n 
A 1 360  ILE 360  360  360  ILE ILE A . n 
A 1 361  LYS 361  361  361  LYS LYS A . n 
A 1 362  GLY 362  362  362  GLY GLY A . n 
A 1 363  LYS 363  363  363  LYS LYS A . n 
A 1 364  ASN 364  364  364  ASN ASN A . n 
A 1 365  GLY 365  365  365  GLY GLY A . n 
A 1 366  VAL 366  366  366  VAL VAL A . n 
A 1 367  PRO 367  367  367  PRO PRO A . n 
A 1 368  LEU 368  368  368  LEU LEU A . n 
A 1 369  LEU 369  369  369  LEU LEU A . n 
A 1 370  PRO 370  370  370  PRO PRO A . n 
A 1 371  GLU 371  371  371  GLU GLU A . n 
A 1 372  LEU 372  372  372  LEU LEU A . n 
A 1 373  TYR 373  373  373  TYR TYR A . n 
A 1 374  SEP 374  374  374  SEP SEP A . n 
A 1 375  VAL 375  375  375  VAL VAL A . n 
A 1 376  PRO 376  376  376  PRO PRO A . n 
A 1 377  PRO 377  377  377  PRO PRO A . n 
A 1 378  ASP 378  378  378  ASP ASP A . n 
A 1 379  ARG 379  379  379  ARG ARG A . n 
A 1 380  VAL 380  380  380  VAL VAL A . n 
A 1 381  ASP 381  381  381  ASP ASP A . n 
A 1 382  GLU 382  382  382  GLU GLU A . n 
A 1 383  GLU 383  383  383  GLU GLU A . n 
A 1 384  TYR 384  384  384  TYR TYR A . n 
A 1 385  GLN 385  385  385  GLN GLN A . n 
A 1 386  ASN 386  386  386  ASN ASN A . n 
A 1 387  PRO 387  387  387  PRO PRO A . n 
A 1 388  HIS 388  388  388  HIS HIS A . n 
A 1 389  THR 389  389  389  THR THR A . n 
A 1 390  VAL 390  390  390  VAL VAL A . n 
A 1 391  ASP 391  391  391  ASP ASP A . n 
A 1 392  ARG 392  392  392  ARG ARG A . n 
A 1 393  VAL 393  393  393  VAL VAL A . n 
A 1 394  PRO 394  394  394  PRO PRO A . n 
A 1 395  MET 395  395  395  MET MET A . n 
A 1 396  GLY 396  396  396  GLY GLY A . n 
A 1 397  LYS 397  397  397  LYS LYS A . n 
A 1 398  LEU 398  398  398  LEU LEU A . n 
A 1 399  PRO 399  399  399  PRO PRO A . n 
A 1 400  HIS 400  400  400  HIS HIS A . n 
A 1 401  MET 401  401  401  MET MET A . n 
A 1 402  TRP 402  402  402  TRP TRP A . n 
A 1 403  GLY 403  403  403  GLY GLY A . n 
A 1 404  GLN 404  404  404  GLN GLN A . n 
A 1 405  SER 405  405  405  SER SER A . n 
A 1 406  LEU 406  406  406  LEU LEU A . n 
A 1 407  TYR 407  407  407  TYR TYR A . n 
A 1 408  ILE 408  408  408  ILE ILE A . n 
A 1 409  LEU 409  409  409  LEU LEU A . n 
A 1 410  GLY 410  410  410  GLY GLY A . n 
A 1 411  SER 411  411  411  SER SER A . n 
A 1 412  LEU 412  412  412  LEU LEU A . n 
A 1 413  MET 413  413  413  MET MET A . n 
A 1 414  ALA 414  414  414  ALA ALA A . n 
A 1 415  GLU 415  415  415  GLU GLU A . n 
A 1 416  GLY 416  416  416  GLY GLY A . n 
A 1 417  PHE 417  417  417  PHE PHE A . n 
A 1 418  LEU 418  418  418  LEU LEU A . n 
A 1 419  ALA 419  419  419  ALA ALA A . n 
A 1 420  PRO 420  420  420  PRO PRO A . n 
A 1 421  GLY 421  421  421  GLY GLY A . n 
A 1 422  GLU 422  422  422  GLU GLU A . n 
A 1 423  ILE 423  423  423  ILE ILE A . n 
A 1 424  ASP 424  424  424  ASP ASP A . n 
A 1 425  PRO 425  425  425  PRO PRO A . n 
A 1 426  LEU 426  426  426  LEU LEU A . n 
A 1 427  ASN 427  427  427  ASN ASN A . n 
A 1 428  ARG 428  428  428  ARG ARG A . n 
A 1 429  ARG 429  429  429  ARG ARG A . n 
A 1 430  PHE 430  430  430  PHE PHE A . n 
A 1 431  SER 431  431  431  SER SER A . n 
A 1 432  THR 432  432  432  THR THR A . n 
A 1 433  VAL 433  433  433  VAL VAL A . n 
A 1 434  PRO 434  434  434  PRO PRO A . n 
A 1 435  LYS 435  435  435  LYS LYS A . n 
A 1 436  PRO 436  436  436  PRO PRO A . n 
A 1 437  ASP 437  437  437  ASP ASP A . n 
A 1 438  VAL 438  438  438  VAL VAL A . n 
A 1 439  VAL 439  439  439  VAL VAL A . n 
A 1 440  VAL 440  440  440  VAL VAL A . n 
A 1 441  GLN 441  441  441  GLN GLN A . n 
A 1 442  VAL 442  442  442  VAL VAL A . n 
A 1 443  SER 443  443  443  SER SER A . n 
A 1 444  ILE 444  444  444  ILE ILE A . n 
A 1 445  LEU 445  445  445  LEU LEU A . n 
A 1 446  ALA 446  446  446  ALA ALA A . n 
A 1 447  GLU 447  447  447  GLU GLU A . n 
A 1 448  THR 448  448  448  THR THR A . n 
A 1 449  GLU 449  449  449  GLU GLU A . n 
A 1 450  GLU 450  450  450  GLU GLU A . n 
A 1 451  ILE 451  451  451  ILE ILE A . n 
A 1 452  LYS 452  452  452  LYS LYS A . n 
A 1 453  THR 453  453  453  THR THR A . n 
A 1 454  ILE 454  454  454  ILE ILE A . n 
A 1 455  LEU 455  455  455  LEU LEU A . n 
A 1 456  LYS 456  456  456  LYS LYS A . n 
A 1 457  ASP 457  457  457  ASP ASP A . n 
A 1 458  LYS 458  458  458  LYS LYS A . n 
A 1 459  GLY 459  459  459  GLY GLY A . n 
A 1 460  ILE 460  460  460  ILE ILE A . n 
A 1 461  TYR 461  461  461  TYR TYR A . n 
A 1 462  VAL 462  462  462  VAL VAL A . n 
A 1 463  GLU 463  463  463  GLU GLU A . n 
A 1 464  THR 464  464  464  THR THR A . n 
A 1 465  ILE 465  465  465  ILE ILE A . n 
A 1 466  ALA 466  466  466  ALA ALA A . n 
A 1 467  GLU 467  467  467  GLU GLU A . n 
A 1 468  VAL 468  468  468  VAL VAL A . n 
A 1 469  TYR 469  469  469  TYR TYR A . n 
A 1 470  PRO 470  470  470  PRO PRO A . n 
A 1 471  ILE 471  471  471  ILE ILE A . n 
A 1 472  ARG 472  472  472  ARG ARG A . n 
A 1 473  VAL 473  473  473  VAL VAL A . n 
A 1 474  GLN 474  474  474  GLN GLN A . n 
A 1 475  PRO 475  475  475  PRO PRO A . n 
A 1 476  ALA 476  476  476  ALA ALA A . n 
A 1 477  ARG 477  477  477  ARG ARG A . n 
A 1 478  ILE 478  478  478  ILE ILE A . n 
A 1 479  LEU 479  479  479  LEU LEU A . n 
A 1 480  SEP 480  480  480  SEP SEP A . n 
A 1 481  HIS 481  481  481  HIS HIS A . n 
A 1 482  ILE 482  482  482  ILE ILE A . n 
A 1 483  TYR 483  483  483  TYR TYR A . n 
A 1 484  SER 484  484  484  SER SER A . n 
A 1 485  SER 485  485  485  SER SER A . n 
A 1 486  LEU 486  486  486  LEU LEU A . n 
A 1 487  GLY 487  487  487  GLY GLY A . n 
A 1 488  CYS 488  488  488  CYS CYS A . n 
A 1 489  ASN 489  489  489  ASN ASN A . n 
A 1 490  ASN 490  490  490  ASN ASN A . n 
A 1 491  ARG 491  491  491  ARG ARG A . n 
A 1 492  MET 492  492  492  MET MET A . n 
A 1 493  LYS 493  493  493  LYS LYS A . n 
A 1 494  LEU 494  494  494  LEU LEU A . n 
A 1 495  SER 495  495  495  SER SER A . n 
A 1 496  GLY 496  496  496  GLY GLY A . n 
A 1 497  ARG 497  497  497  ARG ARG A . n 
A 1 498  PRO 498  498  498  PRO PRO A . n 
A 1 499  TYR 499  499  499  TYR TYR A . n 
A 1 500  ARG 500  500  500  ARG ARG A . n 
A 1 501  HIS 501  501  501  HIS HIS A . n 
A 1 502  MET 502  502  502  MET MET A . n 
A 1 503  GLY 503  503  503  GLY GLY A . n 
A 1 504  VAL 504  504  504  VAL VAL A . n 
A 1 505  LEU 505  505  505  LEU LEU A . n 
A 1 506  GLY 506  506  506  GLY GLY A . n 
A 1 507  THR 507  507  507  THR THR A . n 
A 1 508  SER 508  508  508  SER SER A . n 
A 1 509  LYS 509  509  509  LYS LYS A . n 
A 1 510  LEU 510  510  510  LEU LEU A . n 
A 1 511  TYR 511  511  511  TYR TYR A . n 
A 1 512  ASP 512  512  512  ASP ASP A . n 
A 1 513  ILE 513  513  513  ILE ILE A . n 
A 1 514  ARG 514  514  514  ARG ARG A . n 
A 1 515  LYS 515  515  515  LYS LYS A . n 
A 1 516  THR 516  516  516  THR THR A . n 
A 1 517  ILE 517  517  517  ILE ILE A . n 
A 1 518  PHE 518  518  518  PHE PHE A . n 
A 1 519  THR 519  519  519  THR THR A . n 
A 1 520  PHE 520  520  520  PHE PHE A . n 
A 1 521  THR 521  521  521  THR THR A . n 
A 1 522  PRO 522  522  522  PRO PRO A . n 
A 1 523  GLN 523  523  523  GLN GLN A . n 
A 1 524  PHE 524  524  524  PHE PHE A . n 
A 1 525  ILE 525  525  525  ILE ILE A . n 
A 1 526  ASP 526  526  526  ASP ASP A . n 
A 1 527  GLN 527  527  527  GLN GLN A . n 
A 1 528  GLN 528  528  528  GLN GLN A . n 
A 1 529  GLN 529  529  529  GLN GLN A . n 
A 1 530  PHE 530  530  530  PHE PHE A . n 
A 1 531  TYR 531  531  531  TYR TYR A . n 
A 1 532  LEU 532  532  532  LEU LEU A . n 
A 1 533  ALA 533  533  533  ALA ALA A . n 
A 1 534  LEU 534  534  534  LEU LEU A . n 
A 1 535  ASP 535  535  535  ASP ASP A . n 
A 1 536  ASN 536  536  536  ASN ASN A . n 
A 1 537  LYS 537  537  537  LYS LYS A . n 
A 1 538  MET 538  538  538  MET MET A . n 
A 1 539  ILE 539  539  539  ILE ILE A . n 
A 1 540  VAL 540  540  540  VAL VAL A . n 
A 1 541  GLU 541  541  541  GLU GLU A . n 
A 1 542  MET 542  542  542  MET MET A . n 
A 1 543  LEU 543  543  543  LEU LEU A . n 
A 1 544  ARG 544  544  544  ARG ARG A . n 
A 1 545  THR 545  545  545  THR THR A . n 
A 1 546  ASP 546  546  546  ASP ASP A . n 
A 1 547  LEU 547  547  547  LEU LEU A . n 
A 1 548  SEP 548  548  548  SEP SEP A . n 
A 1 549  TYR 549  549  549  TYR TYR A . n 
A 1 550  LEU 550  550  550  LEU LEU A . n 
A 1 551  CYS 551  551  551  CYS CYS A . n 
A 1 552  SER 552  552  552  SER SER A . n 
A 1 553  ARG 553  553  553  ARG ARG A . n 
A 1 554  TRP 554  554  554  TRP TRP A . n 
A 1 555  ARG 555  555  555  ARG ARG A . n 
A 1 556  MET 556  556  556  MET MET A . n 
A 1 557  THR 557  557  557  THR THR A . n 
A 1 558  GLY 558  558  558  GLY GLY A . n 
A 1 559  GLN 559  559  559  GLN GLN A . n 
A 1 560  PRO 560  560  560  PRO PRO A . n 
A 1 561  THR 561  561  561  THR THR A . n 
A 1 562  ILE 562  562  562  ILE ILE A . n 
A 1 563  THR 563  563  563  THR THR A . n 
A 1 564  PHE 564  564  564  PHE PHE A . n 
A 1 565  PRO 565  565  565  PRO PRO A . n 
A 1 566  ILE 566  566  566  ILE ILE A . n 
A 1 567  SER 567  567  567  SER SER A . n 
A 1 568  HIS 568  568  568  HIS HIS A . n 
A 1 569  SER 569  569  569  SER SER A . n 
A 1 570  MET 570  570  570  MET MET A . n 
A 1 571  LEU 571  571  571  LEU LEU A . n 
A 1 572  ASP 572  572  572  ASP ASP A . n 
A 1 573  GLU 573  573  573  GLU GLU A . n 
A 1 574  ASP 574  574  574  ASP ASP A . n 
A 1 575  GLY 575  575  575  GLY GLY A . n 
A 1 576  THR 576  576  576  THR THR A . n 
A 1 577  SER 577  577  577  SER SER A . n 
A 1 578  LEU 578  578  578  LEU LEU A . n 
A 1 579  ASN 579  579  579  ASN ASN A . n 
A 1 580  SER 580  580  580  SER SER A . n 
A 1 581  SER 581  581  581  SER SER A . n 
A 1 582  ILE 582  582  582  ILE ILE A . n 
A 1 583  LEU 583  583  583  LEU LEU A . n 
A 1 584  ALA 584  584  584  ALA ALA A . n 
A 1 585  ALA 585  585  585  ALA ALA A . n 
A 1 586  LEU 586  586  586  LEU LEU A . n 
A 1 587  ARG 587  587  587  ARG ARG A . n 
A 1 588  LYS 588  588  588  LYS LYS A . n 
A 1 589  MET 589  589  589  MET MET A . n 
A 1 590  GLN 590  590  590  GLN GLN A . n 
A 1 591  ASP 591  591  591  ASP ASP A . n 
A 1 592  GLY 592  592  592  GLY GLY A . n 
A 1 593  TYR 593  593  593  TYR TYR A . n 
A 1 594  PHE 594  594  594  PHE PHE A . n 
A 1 595  GLY 595  595  595  GLY GLY A . n 
A 1 596  GLY 596  596  596  GLY GLY A . n 
A 1 597  ALA 597  597  597  ALA ALA A . n 
A 1 598  ARG 598  598  598  ARG ARG A . n 
A 1 599  VAL 599  599  599  VAL VAL A . n 
A 1 600  GLN 600  600  600  GLN GLN A . n 
A 1 601  THR 601  601  601  THR THR A . n 
A 1 602  GLY 602  602  602  GLY GLY A . n 
A 1 603  LYS 603  603  603  LYS LYS A . n 
A 1 604  LEU 604  604  604  LEU LEU A . n 
A 1 605  SER 605  605  605  SER SER A . n 
A 1 606  GLU 606  606  606  GLU GLU A . n 
A 1 607  PHE 607  607  607  PHE PHE A . n 
A 1 608  LEU 608  608  608  LEU LEU A . n 
A 1 609  THR 609  609  609  THR THR A . n 
A 1 610  THR 610  610  610  THR THR A . n 
A 1 611  SER 611  611  611  SER SER A . n 
A 1 612  CYS 612  612  612  CYS CYS A . n 
A 1 613  CYS 613  613  613  CYS CYS A . n 
A 1 614  THR 614  614  614  THR THR A . n 
A 1 615  HIS 615  615  615  HIS HIS A . n 
A 1 616  LEU 616  616  616  LEU LEU A . n 
A 1 617  SER 617  617  617  SER SER A . n 
A 1 618  PHE 618  618  618  PHE PHE A . n 
A 1 619  MET 619  619  619  MET MET A . n 
A 1 620  ASP 620  620  620  ASP ASP A . n 
A 1 621  PRO 621  621  621  PRO PRO A . n 
A 1 622  GLY 622  622  ?    ?   ?   A . n 
A 1 623  PRO 623  623  ?    ?   ?   A . n 
A 1 624  GLU 624  624  ?    ?   ?   A . n 
A 1 625  GLY 625  625  ?    ?   ?   A . n 
A 1 626  LYS 626  626  ?    ?   ?   A . n 
A 1 627  LEU 627  627  ?    ?   ?   A . n 
A 1 628  TYR 628  628  ?    ?   ?   A . n 
A 1 629  SEP 629  629  ?    ?   ?   A . n 
A 1 630  GLU 630  630  ?    ?   ?   A . n 
A 1 631  ASP 631  631  ?    ?   ?   A . n 
A 1 632  TYR 632  632  ?    ?   ?   A . n 
A 1 633  ASP 633  633  ?    ?   ?   A . n 
A 1 634  ASP 634  634  ?    ?   ?   A . n 
A 1 635  ASN 635  635  ?    ?   ?   A . n 
A 1 636  TYR 636  636  ?    ?   ?   A . n 
A 1 637  ASP 637  637  ?    ?   ?   A . n 
A 1 638  TYR 638  638  ?    ?   ?   A . n 
A 1 639  LEU 639  639  ?    ?   ?   A . n 
A 1 640  GLU 640  640  ?    ?   ?   A . n 
A 1 641  SER 641  641  ?    ?   ?   A . n 
A 1 642  GLY 642  642  ?    ?   ?   A . n 
A 1 643  ASN 643  643  ?    ?   ?   A . n 
A 1 644  TRP 644  644  ?    ?   ?   A . n 
A 1 645  MET 645  645  ?    ?   ?   A . n 
A 1 646  ASN 646  646  ?    ?   ?   A . n 
A 1 647  ASP 647  647  ?    ?   ?   A . n 
A 1 648  TYR 648  648  ?    ?   ?   A . n 
A 1 649  ASP 649  649  ?    ?   ?   A . n 
A 1 650  SER 650  650  ?    ?   ?   A . n 
A 1 651  THR 651  651  ?    ?   ?   A . n 
A 1 652  SER 652  652  ?    ?   ?   A . n 
A 1 653  HIS 653  653  ?    ?   ?   A . n 
A 1 654  ALA 654  654  ?    ?   ?   A . n 
A 1 655  ARG 655  655  ?    ?   ?   A . n 
A 1 656  CYS 656  656  ?    ?   ?   A . n 
A 1 657  GLY 657  657  ?    ?   ?   A . n 
A 1 658  ASP 658  658  ?    ?   ?   A . n 
A 1 659  GLU 659  659  ?    ?   ?   A . n 
A 1 660  VAL 660  660  ?    ?   ?   A . n 
A 1 661  ALA 661  661  ?    ?   ?   A . n 
A 1 662  ARG 662  662  ?    ?   ?   A . n 
A 1 663  TYR 663  663  ?    ?   ?   A . n 
A 1 664  LEU 664  664  ?    ?   ?   A . n 
A 1 665  ASP 665  665  ?    ?   ?   A . n 
A 1 666  HIS 666  666  ?    ?   ?   A . n 
A 1 667  LEU 667  667  ?    ?   ?   A . n 
A 1 668  LEU 668  668  ?    ?   ?   A . n 
A 1 669  ALA 669  669  ?    ?   ?   A . n 
A 1 670  HIS 670  670  ?    ?   ?   A . n 
A 1 671  TPO 671  671  ?    ?   ?   A . n 
A 1 672  ALA 672  672  ?    ?   ?   A . n 
A 1 673  PRO 673  673  ?    ?   ?   A . n 
A 1 674  HIS 674  674  ?    ?   ?   A . n 
A 1 675  PRO 675  675  ?    ?   ?   A . n 
A 1 676  LYS 676  676  ?    ?   ?   A . n 
A 1 677  LEU 677  677  ?    ?   ?   A . n 
A 1 678  ALA 678  678  ?    ?   ?   A . n 
A 1 679  PRO 679  679  ?    ?   ?   A . n 
A 1 680  THR 680  680  ?    ?   ?   A . n 
A 1 681  SER 681  681  ?    ?   ?   A . n 
A 1 682  GLN 682  682  ?    ?   ?   A . n 
A 1 683  LYS 683  683  ?    ?   ?   A . n 
A 1 684  GLY 684  684  ?    ?   ?   A . n 
A 1 685  GLY 685  685  ?    ?   ?   A . n 
A 1 686  LEU 686  686  ?    ?   ?   A . n 
A 1 687  ASP 687  687  ?    ?   ?   A . n 
A 1 688  ARG 688  688  ?    ?   ?   A . n 
A 1 689  PHE 689  689  ?    ?   ?   A . n 
A 1 690  GLN 690  690  ?    ?   ?   A . n 
A 1 691  ALA 691  691  ?    ?   ?   A . n 
A 1 692  ALA 692  692  ?    ?   ?   A . n 
A 1 693  VAL 693  693  ?    ?   ?   A . n 
A 1 694  GLN 694  694  ?    ?   ?   A . n 
A 1 695  THR 695  695  ?    ?   ?   A . n 
A 1 696  THR 696  696  ?    ?   ?   A . n 
A 1 697  CYS 697  697  ?    ?   ?   A . n 
A 1 698  ASP 698  698  ?    ?   ?   A . n 
A 1 699  LEU 699  699  ?    ?   ?   A . n 
A 1 700  MET 700  700  ?    ?   ?   A . n 
A 1 701  SEP 701  701  ?    ?   ?   A . n 
A 1 702  LEU 702  702  ?    ?   ?   A . n 
A 1 703  VAL 703  703  ?    ?   ?   A . n 
A 1 704  THR 704  704  ?    ?   ?   A . n 
A 1 705  LYS 705  705  ?    ?   ?   A . n 
A 1 706  ALA 706  706  ?    ?   ?   A . n 
A 1 707  LYS 707  707  ?    ?   ?   A . n 
A 1 708  GLU 708  708  ?    ?   ?   A . n 
A 1 709  LEU 709  709  ?    ?   ?   A . n 
A 1 710  HIS 710  710  ?    ?   ?   A . n 
A 1 711  VAL 711  711  ?    ?   ?   A . n 
A 1 712  GLN 712  712  ?    ?   ?   A . n 
A 1 713  ASN 713  713  ?    ?   ?   A . n 
A 1 714  VAL 714  714  ?    ?   ?   A . n 
A 1 715  HIS 715  715  ?    ?   ?   A . n 
A 1 716  MET 716  716  ?    ?   ?   A . n 
A 1 717  TYR 717  717  ?    ?   ?   A . n 
A 1 718  LEU 718  718  ?    ?   ?   A . n 
A 1 719  PRO 719  719  ?    ?   ?   A . n 
A 1 720  THR 720  720  ?    ?   ?   A . n 
A 1 721  LYS 721  721  ?    ?   ?   A . n 
A 1 722  LEU 722  722  ?    ?   ?   A . n 
A 1 723  PHE 723  723  ?    ?   ?   A . n 
A 1 724  GLN 724  724  ?    ?   ?   A . n 
A 1 725  ALA 725  725  ?    ?   ?   A . n 
A 1 726  SEP 726  726  ?    ?   ?   A . n 
A 1 727  ARG 727  727  ?    ?   ?   A . n 
A 1 728  PRO 728  728  ?    ?   ?   A . n 
A 1 729  SEP 729  729  ?    ?   ?   A . n 
A 1 730  PHE 730  730  ?    ?   ?   A . n 
A 1 731  ASN 731  731  ?    ?   ?   A . n 
A 1 732  LEU 732  732  ?    ?   ?   A . n 
A 1 733  LEU 733  733  ?    ?   ?   A . n 
A 1 734  ASP 734  734  ?    ?   ?   A . n 
A 1 735  SEP 735  735  ?    ?   ?   A . n 
A 1 736  PRO 736  736  ?    ?   ?   A . n 
A 1 737  HIS 737  737  ?    ?   ?   A . n 
A 1 738  PRO 738  738  ?    ?   ?   A . n 
A 1 739  ARG 739  739  ?    ?   ?   A . n 
A 1 740  GLN 740  740  ?    ?   ?   A . n 
A 1 741  GLU 741  741  ?    ?   ?   A . n 
A 1 742  ASN 742  742  ?    ?   ?   A . n 
A 1 743  GLN 743  743  ?    ?   ?   A . n 
A 1 744  VAL 744  744  ?    ?   ?   A . n 
A 1 745  PRO 745  745  ?    ?   ?   A . n 
A 1 746  SEP 746  746  ?    ?   ?   A . n 
A 1 747  VAL 747  747  ?    ?   ?   A . n 
A 1 748  ARG 748  748  ?    ?   ?   A . n 
A 1 749  VAL 749  749  ?    ?   ?   A . n 
A 1 750  GLU 750  750  ?    ?   ?   A . n 
A 1 751  ILE 751  751  ?    ?   ?   A . n 
A 1 752  HIS 752  752  ?    ?   ?   A . n 
A 1 753  LEU 753  753  ?    ?   ?   A . n 
A 1 754  PRO 754  754  ?    ?   ?   A . n 
A 1 755  ARG 755  755  ?    ?   ?   A . n 
A 1 756  ASP 756  756  ?    ?   ?   A . n 
A 1 757  GLN 757  757  ?    ?   ?   A . n 
A 1 758  SEP 758  758  ?    ?   ?   A . n 
A 1 759  GLY 759  759  ?    ?   ?   A . n 
A 1 760  GLU 760  760  ?    ?   ?   A . n 
A 1 761  VAL 761  761  ?    ?   ?   A . n 
A 1 762  ASP 762  762  762  ASP ASP A . n 
A 1 763  PHE 763  763  763  PHE PHE A . n 
A 1 764  LYS 764  764  764  LYS LYS A . n 
A 1 765  ALA 765  765  765  ALA ALA A . n 
A 1 766  LEU 766  766  766  LEU LEU A . n 
A 1 767  VAL 767  767  767  VAL VAL A . n 
A 1 768  LEU 768  768  768  LEU LEU A . n 
A 1 769  GLN 769  769  769  GLN GLN A . n 
A 1 770  LEU 770  770  770  LEU LEU A . n 
A 1 771  LYS 771  771  771  LYS LYS A . n 
A 1 772  GLU 772  772  772  GLU GLU A . n 
A 1 773  THR 773  773  773  THR THR A . n 
A 1 774  SER 774  774  774  SER SER A . n 
A 1 775  SER 775  775  775  SER SER A . n 
A 1 776  LEU 776  776  776  LEU LEU A . n 
A 1 777  GLN 777  777  777  GLN GLN A . n 
A 1 778  GLU 778  778  778  GLU GLU A . n 
A 1 779  GLN 779  779  779  GLN GLN A . n 
A 1 780  ALA 780  780  780  ALA ALA A . n 
A 1 781  ASP 781  781  781  ASP ASP A . n 
A 1 782  ILE 782  782  782  ILE ILE A . n 
A 1 783  LEU 783  783  783  LEU LEU A . n 
A 1 784  TYR 784  784  784  TYR TYR A . n 
A 1 785  MET 785  785  785  MET MET A . n 
A 1 786  LEU 786  786  786  LEU LEU A . n 
A 1 787  TYR 787  787  787  TYR TYR A . n 
A 1 788  THR 788  788  788  THR THR A . n 
A 1 789  MET 789  789  789  MET MET A . n 
A 1 790  LYS 790  790  790  LYS LYS A . n 
A 1 791  GLY 791  791  791  GLY GLY A . n 
A 1 792  PRO 792  792  792  PRO PRO A . n 
A 1 793  ASP 793  793  793  ASP ASP A . n 
A 1 794  TRP 794  794  794  TRP TRP A . n 
A 1 795  ASN 795  795  795  ASN ASN A . n 
A 1 796  THR 796  796  796  THR THR A . n 
A 1 797  GLU 797  797  797  GLU GLU A . n 
A 1 798  LEU 798  798  798  LEU LEU A . n 
A 1 799  TYR 799  799  799  TYR TYR A . n 
A 1 800  ASN 800  800  800  ASN ASN A . n 
A 1 801  GLU 801  801  801  GLU GLU A . n 
A 1 802  ARG 802  802  802  ARG ARG A . n 
A 1 803  SER 803  803  803  SER SER A . n 
A 1 804  ALA 804  804  804  ALA ALA A . n 
A 1 805  THR 805  805  805  THR THR A . n 
A 1 806  VAL 806  806  806  VAL VAL A . n 
A 1 807  ARG 807  807  807  ARG ARG A . n 
A 1 808  GLU 808  808  808  GLU GLU A . n 
A 1 809  LEU 809  809  809  LEU LEU A . n 
A 1 810  LEU 810  810  810  LEU LEU A . n 
A 1 811  THR 811  811  811  THR THR A . n 
A 1 812  GLU 812  812  812  GLU GLU A . n 
A 1 813  LEU 813  813  813  LEU LEU A . n 
A 1 814  TYR 814  814  814  TYR TYR A . n 
A 1 815  GLY 815  815  815  GLY GLY A . n 
A 1 816  LYS 816  816  816  LYS LYS A . n 
A 1 817  VAL 817  817  817  VAL VAL A . n 
A 1 818  GLY 818  818  818  GLY GLY A . n 
A 1 819  GLU 819  819  819  GLU GLU A . n 
A 1 820  ILE 820  820  820  ILE ILE A . n 
A 1 821  ARG 821  821  821  ARG ARG A . n 
A 1 822  HIS 822  822  822  HIS HIS A . n 
A 1 823  TRP 823  823  823  TRP TRP A . n 
A 1 824  GLY 824  824  824  GLY GLY A . n 
A 1 825  LEU 825  825  825  LEU LEU A . n 
A 1 826  ILE 826  826  826  ILE ILE A . n 
A 1 827  ARG 827  827  827  ARG ARG A . n 
A 1 828  TYR 828  828  828  TYR TYR A . n 
A 1 829  ILE 829  829  829  ILE ILE A . n 
A 1 830  SER 830  830  830  SER SER A . n 
A 1 831  GLY 831  831  831  GLY GLY A . n 
A 1 832  ILE 832  832  832  ILE ILE A . n 
A 1 833  LEU 833  833  833  LEU LEU A . n 
A 1 834  ARG 834  834  834  ARG ARG A . n 
A 1 835  LYS 835  835  835  LYS LYS A . n 
A 1 836  LYS 836  836  836  LYS LYS A . n 
A 1 837  VAL 837  837  837  VAL VAL A . n 
A 1 838  GLU 838  838  838  GLU GLU A . n 
A 1 839  ALA 839  839  839  ALA ALA A . n 
A 1 840  LEU 840  840  840  LEU LEU A . n 
A 1 841  ASP 841  841  841  ASP ASP A . n 
A 1 842  GLU 842  842  842  GLU GLU A . n 
A 1 843  ALA 843  843  843  ALA ALA A . n 
A 1 844  CYS 844  844  844  CYS CYS A . n 
A 1 845  THR 845  845  845  THR THR A . n 
A 1 846  ASP 846  846  846  ASP ASP A . n 
A 1 847  LEU 847  847  847  LEU LEU A . n 
A 1 848  LEU 848  848  848  LEU LEU A . n 
A 1 849  SER 849  849  849  SER SER A . n 
A 1 850  HIS 850  850  850  HIS HIS A . n 
A 1 851  GLN 851  851  851  GLN GLN A . n 
A 1 852  LYS 852  852  852  LYS LYS A . n 
A 1 853  HIS 853  853  853  HIS HIS A . n 
A 1 854  LEU 854  854  854  LEU LEU A . n 
A 1 855  TPO 855  855  855  TPO TPO A . n 
A 1 856  VAL 856  856  856  VAL VAL A . n 
A 1 857  GLY 857  857  857  GLY GLY A . n 
A 1 858  LEU 858  858  858  LEU LEU A . n 
A 1 859  PRO 859  859  859  PRO PRO A . n 
A 1 860  PRO 860  860  860  PRO PRO A . n 
A 1 861  GLU 861  861  861  GLU GLU A . n 
A 1 862  PRO 862  862  862  PRO PRO A . n 
A 1 863  ARG 863  863  863  ARG ARG A . n 
A 1 864  GLU 864  864  864  GLU GLU A . n 
A 1 865  LYS 865  865  865  LYS LYS A . n 
A 1 866  THR 866  866  866  THR THR A . n 
A 1 867  ILE 867  867  867  ILE ILE A . n 
A 1 868  SER 868  868  868  SER SER A . n 
A 1 869  ALA 869  869  869  ALA ALA A . n 
A 1 870  PRO 870  870  870  PRO PRO A . n 
A 1 871  LEU 871  871  871  LEU LEU A . n 
A 1 872  PRO 872  872  872  PRO PRO A . n 
A 1 873  TYR 873  873  873  TYR TYR A . n 
A 1 874  GLU 874  874  874  GLU GLU A . n 
A 1 875  ALA 875  875  875  ALA ALA A . n 
A 1 876  LEU 876  876  876  LEU LEU A . n 
A 1 877  THR 877  877  877  THR THR A . n 
A 1 878  GLN 878  878  878  GLN GLN A . n 
A 1 879  LEU 879  879  879  LEU LEU A . n 
A 1 880  ILE 880  880  880  ILE ILE A . n 
A 1 881  ASP 881  881  881  ASP ASP A . n 
A 1 882  GLU 882  882  882  GLU GLU A . n 
A 1 883  ALA 883  883  883  ALA ALA A . n 
A 1 884  SER 884  884  884  SER SER A . n 
A 1 885  GLU 885  885  885  GLU GLU A . n 
A 1 886  GLY 886  886  886  GLY GLY A . n 
A 1 887  ASP 887  887  887  ASP ASP A . n 
A 1 888  MET 888  888  888  MET MET A . n 
A 1 889  SER 889  889  889  SER SER A . n 
A 1 890  ILE 890  890  890  ILE ILE A . n 
A 1 891  SER 891  891  891  SER SER A . n 
A 1 892  ILE 892  892  892  ILE ILE A . n 
A 1 893  LEU 893  893  893  LEU LEU A . n 
A 1 894  THR 894  894  894  THR THR A . n 
A 1 895  GLN 895  895  895  GLN GLN A . n 
A 1 896  GLU 896  896  896  GLU GLU A . n 
A 1 897  ILE 897  897  897  ILE ILE A . n 
A 1 898  MET 898  898  898  MET MET A . n 
A 1 899  VAL 899  899  899  VAL VAL A . n 
A 1 900  TYR 900  900  900  TYR TYR A . n 
A 1 901  LEU 901  901  901  LEU LEU A . n 
A 1 902  ALA 902  902  902  ALA ALA A . n 
A 1 903  MET 903  903  903  MET MET A . n 
A 1 904  TYR 904  904  904  TYR TYR A . n 
A 1 905  MET 905  905  905  MET MET A . n 
A 1 906  ARG 906  906  906  ARG ARG A . n 
A 1 907  THR 907  907  907  THR THR A . n 
A 1 908  GLN 908  908  908  GLN GLN A . n 
A 1 909  PRO 909  909  909  PRO PRO A . n 
A 1 910  GLY 910  910  910  GLY GLY A . n 
A 1 911  LEU 911  911  911  LEU LEU A . n 
A 1 912  PHE 912  912  912  PHE PHE A . n 
A 1 913  ALA 913  913  913  ALA ALA A . n 
A 1 914  GLU 914  914  914  GLU GLU A . n 
A 1 915  MET 915  915  915  MET MET A . n 
A 1 916  PHE 916  916  916  PHE PHE A . n 
A 1 917  ARG 917  917  917  ARG ARG A . n 
A 1 918  LEU 918  918  918  LEU LEU A . n 
A 1 919  ARG 919  919  919  ARG ARG A . n 
A 1 920  ILE 920  920  920  ILE ILE A . n 
A 1 921  GLY 921  921  921  GLY GLY A . n 
A 1 922  LEU 922  922  922  LEU LEU A . n 
A 1 923  ILE 923  923  923  ILE ILE A . n 
A 1 924  ILE 924  924  924  ILE ILE A . n 
A 1 925  GLN 925  925  925  GLN GLN A . n 
A 1 926  VAL 926  926  926  VAL VAL A . n 
A 1 927  MET 927  927  927  MET MET A . n 
A 1 928  ALA 928  928  928  ALA ALA A . n 
A 1 929  THR 929  929  929  THR THR A . n 
A 1 930  GLU 930  930  930  GLU GLU A . n 
A 1 931  LEU 931  931  931  LEU LEU A . n 
A 1 932  ALA 932  932  932  ALA ALA A . n 
A 1 933  HIS 933  933  933  HIS HIS A . n 
A 1 934  SER 934  934  934  SER SER A . n 
A 1 935  LEU 935  935  935  LEU LEU A . n 
A 1 936  ARG 936  936  936  ARG ARG A . n 
A 1 937  CYS 937  937  937  CYS CYS A . n 
A 1 938  SER 938  938  938  SER SER A . n 
A 1 939  ALA 939  939  939  ALA ALA A . n 
A 1 940  GLU 940  940  940  GLU GLU A . n 
A 1 941  GLU 941  941  941  GLU GLU A . n 
A 1 942  ALA 942  942  942  ALA ALA A . n 
A 1 943  THR 943  943  943  THR THR A . n 
A 1 944  GLU 944  944  944  GLU GLU A . n 
A 1 945  GLY 945  945  945  GLY GLY A . n 
A 1 946  LEU 946  946  946  LEU LEU A . n 
A 1 947  MET 947  947  947  MET MET A . n 
A 1 948  ASN 948  948  948  ASN ASN A . n 
A 1 949  LEU 949  949  949  LEU LEU A . n 
A 1 950  SER 950  950  950  SER SER A . n 
A 1 951  PRO 951  951  951  PRO PRO A . n 
A 1 952  SER 952  952  952  SER SER A . n 
A 1 953  ALA 953  953  953  ALA ALA A . n 
A 1 954  MET 954  954  954  MET MET A . n 
A 1 955  LYS 955  955  955  LYS LYS A . n 
A 1 956  ASN 956  956  956  ASN ASN A . n 
A 1 957  LEU 957  957  957  LEU LEU A . n 
A 1 958  LEU 958  958  958  LEU LEU A . n 
A 1 959  HIS 959  959  959  HIS HIS A . n 
A 1 960  HIS 960  960  960  HIS HIS A . n 
A 1 961  ILE 961  961  961  ILE ILE A . n 
A 1 962  LEU 962  962  962  LEU LEU A . n 
A 1 963  SEP 963  963  963  SEP SEP A . n 
A 1 964  GLY 964  964  964  GLY GLY A . n 
A 1 965  LYS 965  965  965  LYS LYS A . n 
A 1 966  GLU 966  966  966  GLU GLU A . n 
A 1 967  PHE 967  967  ?    ?   ?   A . n 
A 1 968  GLY 968  968  ?    ?   ?   A . n 
A 1 969  VAL 969  969  ?    ?   ?   A . n 
A 1 970  GLU 970  970  ?    ?   ?   A . n 
A 1 971  ARG 971  971  ?    ?   ?   A . n 
A 1 972  SEP 972  972  ?    ?   ?   A . n 
A 1 973  VAL 973  973  ?    ?   ?   A . n 
A 1 974  ARG 974  974  ?    ?   ?   A . n 
A 1 975  PRO 975  975  ?    ?   ?   A . n 
A 1 976  THR 976  976  ?    ?   ?   A . n 
A 1 977  ASP 977  977  ?    ?   ?   A . n 
A 1 978  SER 978  978  ?    ?   ?   A . n 
A 1 979  ASN 979  979  ?    ?   ?   A . n 
A 1 980  VAL 980  980  ?    ?   ?   A . n 
A 1 981  SEP 981  981  ?    ?   ?   A . n 
A 1 982  PRO 982  982  ?    ?   ?   A . n 
A 1 983  ALA 983  983  ?    ?   ?   A . n 
A 1 984  ILE 984  984  ?    ?   ?   A . n 
A 1 985  SEP 985  985  ?    ?   ?   A . n 
A 1 986  ILE 986  986  ?    ?   ?   A . n 
A 1 987  HIS 987  987  ?    ?   ?   A . n 
A 1 988  GLU 988  988  ?    ?   ?   A . n 
A 1 989  ILE 989  989  ?    ?   ?   A . n 
A 1 990  GLY 990  990  ?    ?   ?   A . n 
A 1 991  ALA 991  991  ?    ?   ?   A . n 
A 1 992  VAL 992  992  ?    ?   ?   A . n 
A 1 993  GLY 993  993  ?    ?   ?   A . n 
A 1 994  ALA 994  994  ?    ?   ?   A . n 
A 1 995  TPO 995  995  ?    ?   ?   A . n 
A 1 996  LYS 996  996  ?    ?   ?   A . n 
A 1 997  THR 997  997  ?    ?   ?   A . n 
A 1 998  GLU 998  998  ?    ?   ?   A . n 
A 1 999  ARG 999  999  ?    ?   ?   A . n 
A 1 1000 TPO 1000 1000 ?    ?   ?   A . n 
A 1 1001 GLY 1001 1001 ?    ?   ?   A . n 
A 1 1002 ILE 1002 1002 ?    ?   ?   A . n 
A 1 1003 MET 1003 1003 ?    ?   ?   A . n 
A 1 1004 GLN 1004 1004 ?    ?   ?   A . n 
A 1 1005 LEU 1005 1005 ?    ?   ?   A . n 
A 1 1006 LYS 1006 1006 ?    ?   ?   A . n 
A 1 1007 SEP 1007 1007 ?    ?   ?   A . n 
A 1 1008 GLU 1008 1008 ?    ?   ?   A . n 
A 1 1009 ILE 1009 1009 ?    ?   ?   A . n 
A 1 1010 LYS 1010 1010 ?    ?   ?   A . n 
A 1 1011 GLN 1011 1011 ?    ?   ?   A . n 
A 1 1012 VAL 1012 1012 ?    ?   ?   A . n 
A 1 1013 GLU 1013 1013 ?    ?   ?   A . n 
A 1 1014 PHE 1014 1014 ?    ?   ?   A . n 
A 1 1015 ARG 1015 1015 ?    ?   ?   A . n 
A 1 1016 ARG 1016 1016 ?    ?   ?   A . n 
A 1 1017 LEU 1017 1017 ?    ?   ?   A . n 
A 1 1018 SEP 1018 1018 ?    ?   ?   A . n 
A 1 1019 ILE 1019 1019 ?    ?   ?   A . n 
A 1 1020 SEP 1020 1020 ?    ?   ?   A . n 
A 1 1021 ALA 1021 1021 ?    ?   ?   A . n 
A 1 1022 GLU 1022 1022 ?    ?   ?   A . n 
A 1 1023 SEP 1023 1023 ?    ?   ?   A . n 
A 1 1024 GLN 1024 1024 ?    ?   ?   A . n 
A 1 1025 SEP 1025 1025 ?    ?   ?   A . n 
A 1 1026 PRO 1026 1026 ?    ?   ?   A . n 
A 1 1027 GLY 1027 1027 ?    ?   ?   A . n 
A 1 1028 THR 1028 1028 ?    ?   ?   A . n 
A 1 1029 SER 1029 1029 ?    ?   ?   A . n 
A 1 1030 MET 1030 1030 ?    ?   ?   A . n 
A 1 1031 TPO 1031 1031 ?    ?   ?   A . n 
A 1 1032 PRO 1032 1032 ?    ?   ?   A . n 
A 1 1033 SER 1033 1033 ?    ?   ?   A . n 
A 1 1034 SER 1034 1034 ?    ?   ?   A . n 
A 1 1035 GLY 1035 1035 ?    ?   ?   A . n 
A 1 1036 SER 1036 1036 ?    ?   ?   A . n 
A 1 1037 PHE 1037 1037 ?    ?   ?   A . n 
A 1 1038 PRO 1038 1038 ?    ?   ?   A . n 
A 1 1039 SER 1039 1039 ?    ?   ?   A . n 
A 1 1040 ALA 1040 1040 ?    ?   ?   A . n 
A 1 1041 TYR 1041 1041 ?    ?   ?   A . n 
A 1 1042 ASP 1042 1042 ?    ?   ?   A . n 
A 1 1043 GLN 1043 1043 ?    ?   ?   A . n 
A 1 1044 GLN 1044 1044 ?    ?   ?   A . n 
A 1 1045 SER 1045 1045 ?    ?   ?   A . n 
A 1 1046 SER 1046 1046 ?    ?   ?   A . n 
A 1 1047 LYS 1047 1047 ?    ?   ?   A . n 
A 1 1048 ASP 1048 1048 ?    ?   ?   A . n 
A 1 1049 SER 1049 1049 ?    ?   ?   A . n 
A 1 1050 ARG 1050 1050 ?    ?   ?   A . n 
A 1 1051 GLN 1051 1051 ?    ?   ?   A . n 
A 1 1052 GLY 1052 1052 ?    ?   ?   A . n 
A 1 1053 GLN 1053 1053 1053 GLN GLN A . n 
A 1 1054 TRP 1054 1054 1054 TRP TRP A . n 
A 1 1055 GLN 1055 1055 1055 GLN GLN A . n 
A 1 1056 ARG 1056 1056 1056 ARG ARG A . n 
A 1 1057 ARG 1057 1057 1057 ARG ARG A . n 
A 1 1058 ARG 1058 1058 1058 ARG ARG A . n 
A 1 1059 ARG 1059 1059 1059 ARG ARG A . n 
A 1 1060 LEU 1060 1060 1060 LEU LEU A . n 
A 1 1061 ASP 1061 1061 1061 ASP ASP A . n 
A 1 1062 GLY 1062 1062 1062 GLY GLY A . n 
A 1 1063 ALA 1063 1063 1063 ALA ALA A . n 
A 1 1064 LEU 1064 1064 1064 LEU LEU A . n 
A 1 1065 ASN 1065 1065 1065 ASN ASN A . n 
A 1 1066 ARG 1066 1066 1066 ARG ARG A . n 
A 1 1067 VAL 1067 1067 1067 VAL VAL A . n 
A 1 1068 PRO 1068 1068 1068 PRO PRO A . n 
A 1 1069 VAL 1069 1069 1069 VAL VAL A . n 
A 1 1070 GLY 1070 1070 1070 GLY GLY A . n 
A 1 1071 PHE 1071 1071 1071 PHE PHE A . n 
A 1 1072 TYR 1072 1072 1072 TYR TYR A . n 
A 1 1073 GLN 1073 1073 1073 GLN GLN A . n 
A 1 1074 LYS 1074 1074 1074 LYS LYS A . n 
A 1 1075 VAL 1075 1075 1075 VAL VAL A . n 
A 1 1076 TRP 1076 1076 1076 TRP TRP A . n 
A 1 1077 LYS 1077 1077 1077 LYS LYS A . n 
A 1 1078 VAL 1078 1078 1078 VAL VAL A . n 
A 1 1079 LEU 1079 1079 1079 LEU LEU A . n 
A 1 1080 GLN 1080 1080 1080 GLN GLN A . n 
A 1 1081 LYS 1081 1081 1081 LYS LYS A . n 
A 1 1082 CYS 1082 1082 1082 CYS CYS A . n 
A 1 1083 HIS 1083 1083 1083 HIS HIS A . n 
A 1 1084 GLY 1084 1084 1084 GLY GLY A . n 
A 1 1085 LEU 1085 1085 1085 LEU LEU A . n 
A 1 1086 SER 1086 1086 1086 SER SER A . n 
A 1 1087 VAL 1087 1087 1087 VAL VAL A . n 
A 1 1088 GLU 1088 1088 1088 GLU GLU A . n 
A 1 1089 GLY 1089 1089 1089 GLY GLY A . n 
A 1 1090 PHE 1090 1090 1090 PHE PHE A . n 
A 1 1091 VAL 1091 1091 1091 VAL VAL A . n 
A 1 1092 LEU 1092 1092 1092 LEU LEU A . n 
A 1 1093 PRO 1093 1093 1093 PRO PRO A . n 
A 1 1094 SER 1094 1094 1094 SER SER A . n 
A 1 1095 SER 1095 1095 1095 SER SER A . n 
A 1 1096 THR 1096 1096 1096 THR THR A . n 
A 1 1097 THR 1097 1097 1097 THR THR A . n 
A 1 1098 ARG 1098 1098 1098 ARG ARG A . n 
A 1 1099 GLU 1099 1099 1099 GLU GLU A . n 
A 1 1100 MET 1100 1100 1100 MET MET A . n 
A 1 1101 THR 1101 1101 1101 THR THR A . n 
A 1 1102 PRO 1102 1102 1102 PRO PRO A . n 
A 1 1103 GLY 1103 1103 1103 GLY GLY A . n 
A 1 1104 GLU 1104 1104 1104 GLU GLU A . n 
A 1 1105 ILE 1105 1105 1105 ILE ILE A . n 
A 1 1106 LYS 1106 1106 1106 LYS LYS A . n 
A 1 1107 PHE 1107 1107 1107 PHE PHE A . n 
A 1 1108 SER 1108 1108 1108 SER SER A . n 
A 1 1109 VAL 1109 1109 1109 VAL VAL A . n 
A 1 1110 HIS 1110 1110 1110 HIS HIS A . n 
A 1 1111 VAL 1111 1111 1111 VAL VAL A . n 
A 1 1112 GLU 1112 1112 1112 GLU GLU A . n 
A 1 1113 SER 1113 1113 1113 SER SER A . n 
A 1 1114 VAL 1114 1114 1114 VAL VAL A . n 
A 1 1115 LEU 1115 1115 1115 LEU LEU A . n 
A 1 1116 ASN 1116 1116 1116 ASN ASN A . n 
A 1 1117 ARG 1117 1117 1117 ARG ARG A . n 
A 1 1118 VAL 1118 1118 1118 VAL VAL A . n 
A 1 1119 PRO 1119 1119 1119 PRO PRO A . n 
A 1 1120 GLN 1120 1120 1120 GLN GLN A . n 
A 1 1121 PRO 1121 1121 1121 PRO PRO A . n 
A 1 1122 GLU 1122 1122 1122 GLU GLU A . n 
A 1 1123 TYR 1123 1123 1123 TYR TYR A . n 
A 1 1124 ARG 1124 1124 1124 ARG ARG A . n 
A 1 1125 GLN 1125 1125 1125 GLN GLN A . n 
A 1 1126 LEU 1126 1126 1126 LEU LEU A . n 
A 1 1127 LEU 1127 1127 1127 LEU LEU A . n 
A 1 1128 VAL 1128 1128 1128 VAL VAL A . n 
A 1 1129 GLU 1129 1129 1129 GLU GLU A . n 
A 1 1130 ALA 1130 1130 1130 ALA ALA A . n 
A 1 1131 ILE 1131 1131 1131 ILE ILE A . n 
A 1 1132 LEU 1132 1132 1132 LEU LEU A . n 
A 1 1133 VAL 1133 1133 1133 VAL VAL A . n 
A 1 1134 LEU 1134 1134 1134 LEU LEU A . n 
A 1 1135 THR 1135 1135 1135 THR THR A . n 
A 1 1136 MET 1136 1136 1136 MET MET A . n 
A 1 1137 LEU 1137 1137 1137 LEU LEU A . n 
A 1 1138 ALA 1138 1138 1138 ALA ALA A . n 
A 1 1139 ASP 1139 1139 1139 ASP ASP A . n 
A 1 1140 ILE 1140 1140 1140 ILE ILE A . n 
A 1 1141 GLU 1141 1141 1141 GLU GLU A . n 
A 1 1142 ILE 1142 1142 1142 ILE ILE A . n 
A 1 1143 HIS 1143 1143 1143 HIS HIS A . n 
A 1 1144 SER 1144 1144 1144 SER SER A . n 
A 1 1145 ILE 1145 1145 1145 ILE ILE A . n 
A 1 1146 GLY 1146 1146 1146 GLY GLY A . n 
A 1 1147 SER 1147 1147 1147 SER SER A . n 
A 1 1148 ILE 1148 1148 1148 ILE ILE A . n 
A 1 1149 ILE 1149 1149 1149 ILE ILE A . n 
A 1 1150 ALA 1150 1150 1150 ALA ALA A . n 
A 1 1151 VAL 1151 1151 1151 VAL VAL A . n 
A 1 1152 GLU 1152 1152 1152 GLU GLU A . n 
A 1 1153 LYS 1153 1153 1153 LYS LYS A . n 
A 1 1154 ILE 1154 1154 1154 ILE ILE A . n 
A 1 1155 VAL 1155 1155 1155 VAL VAL A . n 
A 1 1156 HIS 1156 1156 1156 HIS HIS A . n 
A 1 1157 ILE 1157 1157 1157 ILE ILE A . n 
A 1 1158 ALA 1158 1158 1158 ALA ALA A . n 
A 1 1159 ASN 1159 1159 1159 ASN ASN A . n 
A 1 1160 ASP 1160 1160 1160 ASP ASP A . n 
A 1 1161 LEU 1161 1161 1161 LEU LEU A . n 
A 1 1162 PHE 1162 1162 1162 PHE PHE A . n 
A 1 1163 LEU 1163 1163 1163 LEU LEU A . n 
A 1 1164 GLN 1164 1164 1164 GLN GLN A . n 
A 1 1165 GLU 1165 1165 1165 GLU GLU A . n 
A 1 1166 GLN 1166 1166 1166 GLN GLN A . n 
A 1 1167 LYS 1167 1167 1167 LYS LYS A . n 
A 1 1168 THR 1168 1168 1168 THR THR A . n 
A 1 1169 LEU 1169 1169 1169 LEU LEU A . n 
A 1 1170 GLY 1170 1170 1170 GLY GLY A . n 
A 1 1171 ALA 1171 1171 1171 ALA ALA A . n 
A 1 1172 ASP 1172 1172 1172 ASP ASP A . n 
A 1 1173 ASP 1173 1173 1173 ASP ASP A . n 
A 1 1174 TPO 1174 1174 1174 TPO TPO A . n 
A 1 1175 MET 1175 1175 1175 MET MET A . n 
A 1 1176 LEU 1176 1176 1176 LEU LEU A . n 
A 1 1177 ALA 1177 1177 1177 ALA ALA A . n 
A 1 1178 LYS 1178 1178 1178 LYS LYS A . n 
A 1 1179 ASP 1179 1179 1179 ASP ASP A . n 
A 1 1180 PRO 1180 1180 1180 PRO PRO A . n 
A 1 1181 ALA 1181 1181 1181 ALA ALA A . n 
A 1 1182 SER 1182 1182 1182 SER SER A . n 
A 1 1183 GLY 1183 1183 1183 GLY GLY A . n 
A 1 1184 ILE 1184 1184 1184 ILE ILE A . n 
A 1 1185 CYS 1185 1185 1185 CYS CYS A . n 
A 1 1186 THR 1186 1186 1186 THR THR A . n 
A 1 1187 LEU 1187 1187 1187 LEU LEU A . n 
A 1 1188 LEU 1188 1188 1188 LEU LEU A . n 
A 1 1189 TYR 1189 1189 1189 TYR TYR A . n 
A 1 1190 ASP 1190 1190 1190 ASP ASP A . n 
A 1 1191 SER 1191 1191 1191 SER SER A . n 
A 1 1192 ALA 1192 1192 1192 ALA ALA A . n 
A 1 1193 PRO 1193 1193 1193 PRO PRO A . n 
A 1 1194 SEP 1194 1194 1194 SEP SEP A . n 
A 1 1195 GLY 1195 1195 1195 GLY GLY A . n 
A 1 1196 ARG 1196 1196 1196 ARG ARG A . n 
A 1 1197 PHE 1197 1197 1197 PHE PHE A . n 
A 1 1198 GLY 1198 1198 1198 GLY GLY A . n 
A 1 1199 THR 1199 1199 1199 THR THR A . n 
A 1 1200 MET 1200 1200 1200 MET MET A . n 
A 1 1201 THR 1201 1201 1201 THR THR A . n 
A 1 1202 TYR 1202 1202 1202 TYR TYR A . n 
A 1 1203 LEU 1203 1203 1203 LEU LEU A . n 
A 1 1204 SER 1204 1204 1204 SER SER A . n 
A 1 1205 LYS 1205 1205 1205 LYS LYS A . n 
A 1 1206 ALA 1206 1206 1206 ALA ALA A . n 
A 1 1207 ALA 1207 1207 1207 ALA ALA A . n 
A 1 1208 ALA 1208 1208 1208 ALA ALA A . n 
A 1 1209 THR 1209 1209 1209 THR THR A . n 
A 1 1210 TYR 1210 1210 1210 TYR TYR A . n 
A 1 1211 VAL 1211 1211 1211 VAL VAL A . n 
A 1 1212 GLN 1212 1212 1212 GLN GLN A . n 
A 1 1213 GLU 1213 1213 1213 GLU GLU A . n 
A 1 1214 PHE 1214 1214 1214 PHE PHE A . n 
A 1 1215 LEU 1215 1215 1215 LEU LEU A . n 
A 1 1216 PRO 1216 1216 1216 PRO PRO A . n 
A 1 1217 HIS 1217 1217 1217 HIS HIS A . n 
A 1 1218 SEP 1218 1218 1218 SEP SEP A . n 
A 1 1219 ILE 1219 1219 1219 ILE ILE A . n 
A 1 1220 CYS 1220 1220 1220 CYS CYS A . n 
A 1 1221 ALA 1221 1221 1221 ALA ALA A . n 
A 1 1222 MET 1222 1222 1222 MET MET A . n 
A 1 1223 GLN 1223 1223 1223 GLN GLN A . n 
B 2 1    MET 1    1    ?    ?   ?   C . n 
B 2 2    THR 2    2    ?    ?   ?   C . n 
B 2 3    ARG 3    3    ?    ?   ?   C . n 
B 2 4    ASP 4    4    ?    ?   ?   C . n 
B 2 5    GLU 5    5    ?    ?   ?   C . n 
B 2 6    ALA 6    6    ?    ?   ?   C . n 
B 2 7    LEU 7    7    ?    ?   ?   C . n 
B 2 8    PRO 8    8    ?    ?   ?   C . n 
B 2 9    ASP 9    9    ?    ?   ?   C . n 
B 2 10   SER 10   10   ?    ?   ?   C . n 
B 2 11   HIS 11   11   ?    ?   ?   C . n 
B 2 12   SER 12   12   12   SER SER C . n 
B 2 13   ALA 13   13   13   ALA ALA C . n 
B 2 14   GLN 14   14   14   GLN GLN C . n 
B 2 15   ASP 15   15   15   ASP ASP C . n 
B 2 16   PHE 16   16   16   PHE PHE C . n 
B 2 17   TYR 17   17   17   TYR TYR C . n 
B 2 18   GLU 18   18   18   GLU GLU C . n 
B 2 19   ASN 19   19   19   ASN ASN C . n 
B 2 20   TYR 20   20   20   TYR TYR C . n 
B 2 21   GLU 21   21   21   GLU GLU C . n 
B 2 22   PRO 22   22   22   PRO PRO C . n 
B 2 23   LYS 23   23   23   LYS LYS C . n 
B 2 24   GLU 24   24   24   GLU GLU C . n 
B 2 25   ILE 25   25   25   ILE ILE C . n 
B 2 26   LEU 26   26   26   LEU LEU C . n 
B 2 27   GLY 27   27   27   GLY GLY C . n 
B 2 28   ARG 28   28   28   ARG ARG C . n 
B 2 29   GLY 29   29   29   GLY GLY C . n 
B 2 30   VAL 30   30   30   VAL VAL C . n 
B 2 31   SER 31   31   31   SER SER C . n 
B 2 32   SER 32   32   32   SER SER C . n 
B 2 33   VAL 33   33   33   VAL VAL C . n 
B 2 34   VAL 34   34   34   VAL VAL C . n 
B 2 35   ARG 35   35   35   ARG ARG C . n 
B 2 36   ARG 36   36   36   ARG ARG C . n 
B 2 37   CYS 37   37   37   CYS CYS C . n 
B 2 38   ILE 38   38   38   ILE ILE C . n 
B 2 39   HIS 39   39   39   HIS HIS C . n 
B 2 40   LYS 40   40   40   LYS LYS C . n 
B 2 41   PRO 41   41   41   PRO PRO C . n 
B 2 42   THR 42   42   42   THR THR C . n 
B 2 43   SER 43   43   43   SER SER C . n 
B 2 44   GLN 44   44   44   GLN GLN C . n 
B 2 45   GLU 45   45   45   GLU GLU C . n 
B 2 46   TYR 46   46   46   TYR TYR C . n 
B 2 47   ALA 47   47   47   ALA ALA C . n 
B 2 48   VAL 48   48   48   VAL VAL C . n 
B 2 49   LYS 49   49   49   LYS LYS C . n 
B 2 50   VAL 50   50   50   VAL VAL C . n 
B 2 51   ILE 51   51   51   ILE ILE C . n 
B 2 52   ASP 52   52   52   ASP ASP C . n 
B 2 53   VAL 53   53   53   VAL VAL C . n 
B 2 54   THR 54   54   54   THR THR C . n 
B 2 55   GLY 55   55   55   GLY GLY C . n 
B 2 56   GLY 56   56   56   GLY GLY C . n 
B 2 57   GLY 57   57   57   GLY GLY C . n 
B 2 58   SER 58   58   58   SER SER C . n 
B 2 59   PHE 59   59   59   PHE PHE C . n 
B 2 60   SER 60   60   60   SER SER C . n 
B 2 61   PRO 61   61   61   PRO PRO C . n 
B 2 62   GLU 62   62   62   GLU GLU C . n 
B 2 63   GLU 63   63   63   GLU GLU C . n 
B 2 64   VAL 64   64   64   VAL VAL C . n 
B 2 65   ARG 65   65   65   ARG ARG C . n 
B 2 66   GLU 66   66   66   GLU GLU C . n 
B 2 67   LEU 67   67   67   LEU LEU C . n 
B 2 68   ARG 68   68   68   ARG ARG C . n 
B 2 69   GLU 69   69   69   GLU GLU C . n 
B 2 70   ALA 70   70   70   ALA ALA C . n 
B 2 71   THR 71   71   71   THR THR C . n 
B 2 72   LEU 72   72   72   LEU LEU C . n 
B 2 73   LYS 73   73   73   LYS LYS C . n 
B 2 74   GLU 74   74   74   GLU GLU C . n 
B 2 75   VAL 75   75   75   VAL VAL C . n 
B 2 76   ASP 76   76   76   ASP ASP C . n 
B 2 77   ILE 77   77   77   ILE ILE C . n 
B 2 78   LEU 78   78   78   LEU LEU C . n 
B 2 79   ARG 79   79   79   ARG ARG C . n 
B 2 80   LYS 80   80   80   LYS LYS C . n 
B 2 81   VAL 81   81   81   VAL VAL C . n 
B 2 82   SER 82   82   82   SER SER C . n 
B 2 83   GLY 83   83   83   GLY GLY C . n 
B 2 84   HIS 84   84   84   HIS HIS C . n 
B 2 85   PRO 85   85   85   PRO PRO C . n 
B 2 86   ASN 86   86   86   ASN ASN C . n 
B 2 87   ILE 87   87   87   ILE ILE C . n 
B 2 88   ILE 88   88   88   ILE ILE C . n 
B 2 89   GLN 89   89   89   GLN GLN C . n 
B 2 90   LEU 90   90   90   LEU LEU C . n 
B 2 91   LYS 91   91   91   LYS LYS C . n 
B 2 92   ASP 92   92   92   ASP ASP C . n 
B 2 93   THR 93   93   93   THR THR C . n 
B 2 94   TYR 94   94   94   TYR TYR C . n 
B 2 95   GLU 95   95   95   GLU GLU C . n 
B 2 96   THR 96   96   96   THR THR C . n 
B 2 97   ASN 97   97   97   ASN ASN C . n 
B 2 98   THR 98   98   98   THR THR C . n 
B 2 99   PHE 99   99   99   PHE PHE C . n 
B 2 100  PHE 100  100  100  PHE PHE C . n 
B 2 101  PHE 101  101  101  PHE PHE C . n 
B 2 102  LEU 102  102  102  LEU LEU C . n 
B 2 103  VAL 103  103  103  VAL VAL C . n 
B 2 104  PHE 104  104  104  PHE PHE C . n 
B 2 105  ASP 105  105  105  ASP ASP C . n 
B 2 106  LEU 106  106  106  LEU LEU C . n 
B 2 107  MET 107  107  107  MET MET C . n 
B 2 108  LYS 108  108  108  LYS LYS C . n 
B 2 109  ARG 109  109  109  ARG ARG C . n 
B 2 110  GLY 110  110  110  GLY GLY C . n 
B 2 111  GLU 111  111  111  GLU GLU C . n 
B 2 112  LEU 112  112  112  LEU LEU C . n 
B 2 113  PHE 113  113  113  PHE PHE C . n 
B 2 114  ASP 114  114  114  ASP ASP C . n 
B 2 115  TYR 115  115  115  TYR TYR C . n 
B 2 116  LEU 116  116  116  LEU LEU C . n 
B 2 117  THR 117  117  117  THR THR C . n 
B 2 118  GLU 118  118  118  GLU GLU C . n 
B 2 119  LYS 119  119  119  LYS LYS C . n 
B 2 120  VAL 120  120  120  VAL VAL C . n 
B 2 121  THR 121  121  121  THR THR C . n 
B 2 122  LEU 122  122  122  LEU LEU C . n 
B 2 123  SER 123  123  123  SER SER C . n 
B 2 124  GLU 124  124  124  GLU GLU C . n 
B 2 125  LYS 125  125  125  LYS LYS C . n 
B 2 126  GLU 126  126  126  GLU GLU C . n 
B 2 127  THR 127  127  127  THR THR C . n 
B 2 128  ARG 128  128  128  ARG ARG C . n 
B 2 129  LYS 129  129  129  LYS LYS C . n 
B 2 130  ILE 130  130  130  ILE ILE C . n 
B 2 131  MET 131  131  131  MET MET C . n 
B 2 132  ARG 132  132  132  ARG ARG C . n 
B 2 133  ALA 133  133  133  ALA ALA C . n 
B 2 134  LEU 134  134  134  LEU LEU C . n 
B 2 135  LEU 135  135  135  LEU LEU C . n 
B 2 136  GLU 136  136  136  GLU GLU C . n 
B 2 137  VAL 137  137  137  VAL VAL C . n 
B 2 138  ILE 138  138  138  ILE ILE C . n 
B 2 139  CYS 139  139  139  CYS CYS C . n 
B 2 140  THR 140  140  140  THR THR C . n 
B 2 141  LEU 141  141  141  LEU LEU C . n 
B 2 142  HIS 142  142  142  HIS HIS C . n 
B 2 143  LYS 143  143  143  LYS LYS C . n 
B 2 144  LEU 144  144  144  LEU LEU C . n 
B 2 145  ASN 145  145  145  ASN ASN C . n 
B 2 146  ILE 146  146  146  ILE ILE C . n 
B 2 147  VAL 147  147  147  VAL VAL C . n 
B 2 148  HIS 148  148  148  HIS HIS C . n 
B 2 149  ARG 149  149  149  ARG ARG C . n 
B 2 150  ASP 150  150  150  ASP ASP C . n 
B 2 151  LEU 151  151  151  LEU LEU C . n 
B 2 152  LYS 152  152  152  LYS LYS C . n 
B 2 153  PRO 153  153  153  PRO PRO C . n 
B 2 154  GLU 154  154  154  GLU GLU C . n 
B 2 155  ASN 155  155  155  ASN ASN C . n 
B 2 156  ILE 156  156  156  ILE ILE C . n 
B 2 157  LEU 157  157  157  LEU LEU C . n 
B 2 158  LEU 158  158  158  LEU LEU C . n 
B 2 159  ASP 159  159  159  ASP ASP C . n 
B 2 160  ASP 160  160  160  ASP ASP C . n 
B 2 161  ASN 161  161  161  ASN ASN C . n 
B 2 162  MET 162  162  162  MET MET C . n 
B 2 163  ASN 163  163  163  ASN ASN C . n 
B 2 164  ILE 164  164  164  ILE ILE C . n 
B 2 165  LYS 165  165  165  LYS LYS C . n 
B 2 166  LEU 166  166  166  LEU LEU C . n 
B 2 167  THR 167  167  167  THR THR C . n 
B 2 168  ASP 168  168  168  ASP ASP C . n 
B 2 169  PHE 169  169  169  PHE PHE C . n 
B 2 170  GLY 170  170  170  GLY GLY C . n 
B 2 171  PHE 171  171  171  PHE PHE C . n 
B 2 172  SER 172  172  172  SER SER C . n 
B 2 173  CYS 173  173  173  CYS CYS C . n 
B 2 174  GLN 174  174  174  GLN GLN C . n 
B 2 175  LEU 175  175  175  LEU LEU C . n 
B 2 176  GLU 176  176  176  GLU GLU C . n 
B 2 177  PRO 177  177  177  PRO PRO C . n 
B 2 178  GLY 178  178  178  GLY GLY C . n 
B 2 179  GLU 179  179  179  GLU GLU C . n 
B 2 180  ARG 180  180  180  ARG ARG C . n 
B 2 181  LEU 181  181  181  LEU LEU C . n 
B 2 182  ARG 182  182  182  ARG ARG C . n 
B 2 183  GLU 183  183  183  GLU GLU C . n 
B 2 184  VAL 184  184  184  VAL VAL C . n 
B 2 185  CYS 185  185  185  CYS CYS C . n 
B 2 186  GLY 186  186  186  GLY GLY C . n 
B 2 187  THR 187  187  187  THR THR C . n 
B 2 188  PRO 188  188  188  PRO PRO C . n 
B 2 189  SER 189  189  189  SER SER C . n 
B 2 190  TYR 190  190  190  TYR TYR C . n 
B 2 191  LEU 191  191  191  LEU LEU C . n 
B 2 192  ALA 192  192  192  ALA ALA C . n 
B 2 193  PRO 193  193  193  PRO PRO C . n 
B 2 194  GLU 194  194  194  GLU GLU C . n 
B 2 195  ILE 195  195  195  ILE ILE C . n 
B 2 196  ILE 196  196  196  ILE ILE C . n 
B 2 197  GLU 197  197  197  GLU GLU C . n 
B 2 198  CYS 198  198  198  CYS CYS C . n 
B 2 199  SER 199  199  199  SER SER C . n 
B 2 200  MET 200  200  200  MET MET C . n 
B 2 201  ASN 201  201  201  ASN ASN C . n 
B 2 202  GLU 202  202  202  GLU GLU C . n 
B 2 203  ASP 203  203  203  ASP ASP C . n 
B 2 204  HIS 204  204  204  HIS HIS C . n 
B 2 205  PRO 205  205  205  PRO PRO C . n 
B 2 206  GLY 206  206  206  GLY GLY C . n 
B 2 207  TYR 207  207  207  TYR TYR C . n 
B 2 208  GLY 208  208  208  GLY GLY C . n 
B 2 209  LYS 209  209  209  LYS LYS C . n 
B 2 210  GLU 210  210  210  GLU GLU C . n 
B 2 211  VAL 211  211  211  VAL VAL C . n 
B 2 212  ASP 212  212  212  ASP ASP C . n 
B 2 213  MET 213  213  213  MET MET C . n 
B 2 214  TRP 214  214  214  TRP TRP C . n 
B 2 215  SER 215  215  215  SER SER C . n 
B 2 216  THR 216  216  216  THR THR C . n 
B 2 217  GLY 217  217  217  GLY GLY C . n 
B 2 218  VAL 218  218  218  VAL VAL C . n 
B 2 219  ILE 219  219  219  ILE ILE C . n 
B 2 220  MET 220  220  220  MET MET C . n 
B 2 221  TYR 221  221  221  TYR TYR C . n 
B 2 222  THR 222  222  222  THR THR C . n 
B 2 223  LEU 223  223  223  LEU LEU C . n 
B 2 224  LEU 224  224  224  LEU LEU C . n 
B 2 225  ALA 225  225  225  ALA ALA C . n 
B 2 226  GLY 226  226  226  GLY GLY C . n 
B 2 227  SER 227  227  227  SER SER C . n 
B 2 228  PRO 228  228  228  PRO PRO C . n 
B 2 229  PRO 229  229  229  PRO PRO C . n 
B 2 230  PHE 230  230  230  PHE PHE C . n 
B 2 231  TRP 231  231  231  TRP TRP C . n 
B 2 232  HIS 232  232  232  HIS HIS C . n 
B 2 233  ARG 233  233  233  ARG ARG C . n 
B 2 234  LYS 234  234  234  LYS LYS C . n 
B 2 235  GLN 235  235  235  GLN GLN C . n 
B 2 236  MET 236  236  236  MET MET C . n 
B 2 237  LEU 237  237  237  LEU LEU C . n 
B 2 238  MET 238  238  238  MET MET C . n 
B 2 239  LEU 239  239  239  LEU LEU C . n 
B 2 240  ARG 240  240  240  ARG ARG C . n 
B 2 241  MET 241  241  241  MET MET C . n 
B 2 242  ILE 242  242  242  ILE ILE C . n 
B 2 243  MET 243  243  243  MET MET C . n 
B 2 244  SER 244  244  244  SER SER C . n 
B 2 245  GLY 245  245  245  GLY GLY C . n 
B 2 246  ASN 246  246  246  ASN ASN C . n 
B 2 247  TYR 247  247  247  TYR TYR C . n 
B 2 248  GLN 248  248  248  GLN GLN C . n 
B 2 249  PHE 249  249  249  PHE PHE C . n 
B 2 250  GLY 250  250  250  GLY GLY C . n 
B 2 251  SER 251  251  251  SER SER C . n 
B 2 252  PRO 252  252  252  PRO PRO C . n 
B 2 253  GLU 253  253  253  GLU GLU C . n 
B 2 254  TRP 254  254  254  TRP TRP C . n 
B 2 255  ASP 255  255  255  ASP ASP C . n 
B 2 256  ASP 256  256  256  ASP ASP C . n 
B 2 257  TYR 257  257  257  TYR TYR C . n 
B 2 258  SER 258  258  258  SER SER C . n 
B 2 259  ASP 259  259  259  ASP ASP C . n 
B 2 260  THR 260  260  260  THR THR C . n 
B 2 261  VAL 261  261  261  VAL VAL C . n 
B 2 262  LYS 262  262  262  LYS LYS C . n 
B 2 263  ASP 263  263  263  ASP ASP C . n 
B 2 264  LEU 264  264  264  LEU LEU C . n 
B 2 265  VAL 265  265  265  VAL VAL C . n 
B 2 266  SER 266  266  266  SER SER C . n 
B 2 267  ARG 267  267  267  ARG ARG C . n 
B 2 268  PHE 268  268  268  PHE PHE C . n 
B 2 269  LEU 269  269  269  LEU LEU C . n 
B 2 270  VAL 270  270  270  VAL VAL C . n 
B 2 271  VAL 271  271  271  VAL VAL C . n 
B 2 272  GLN 272  272  272  GLN GLN C . n 
B 2 273  PRO 273  273  273  PRO PRO C . n 
B 2 274  GLN 274  274  274  GLN GLN C . n 
B 2 275  ASN 275  275  275  ASN ASN C . n 
B 2 276  ARG 276  276  276  ARG ARG C . n 
B 2 277  TYR 277  277  277  TYR TYR C . n 
B 2 278  THR 278  278  278  THR THR C . n 
B 2 279  ALA 279  279  279  ALA ALA C . n 
B 2 280  GLU 280  280  280  GLU GLU C . n 
B 2 281  GLU 281  281  281  GLU GLU C . n 
B 2 282  ALA 282  282  282  ALA ALA C . n 
B 2 283  LEU 283  283  283  LEU LEU C . n 
B 2 284  ALA 284  284  284  ALA ALA C . n 
B 2 285  HIS 285  285  285  HIS HIS C . n 
B 2 286  PRO 286  286  286  PRO PRO C . n 
B 2 287  PHE 287  287  287  PHE PHE C . n 
B 2 288  PHE 288  288  288  PHE PHE C . n 
B 2 289  GLN 289  289  289  GLN GLN C . n 
B 2 290  GLN 290  290  290  GLN GLN C . n 
B 2 291  TYR 291  291  291  TYR TYR C . n 
B 2 292  LEU 292  292  292  LEU LEU C . n 
B 2 293  VAL 293  293  293  VAL VAL C . n 
B 2 294  GLU 294  294  294  GLU GLU C . n 
B 2 295  GLU 295  295  295  GLU GLU C . n 
B 2 296  VAL 296  296  296  VAL VAL C . n 
B 2 297  ARG 297  297  297  ARG ARG C . n 
B 2 298  HIS 298  298  298  HIS HIS C . n 
B 2 299  PHE 299  299  299  PHE PHE C . n 
B 2 300  SER 300  300  300  SER SER C . n 
B 2 301  PRO 301  301  301  PRO PRO C . n 
B 2 302  ARG 302  302  302  ARG ARG C . n 
B 2 303  GLY 303  303  303  GLY GLY C . n 
B 2 304  LYS 304  304  304  LYS LYS C . n 
B 2 305  PHE 305  305  305  PHE PHE C . n 
B 2 306  LYS 306  306  306  LYS LYS C . n 
B 2 307  VAL 307  307  307  VAL VAL C . n 
B 2 308  ILE 308  308  308  ILE ILE C . n 
B 2 309  ALA 309  309  309  ALA ALA C . n 
B 2 310  LEU 310  310  310  LEU LEU C . n 
B 2 311  THR 311  311  311  THR THR C . n 
B 2 312  VAL 312  312  312  VAL VAL C . n 
B 2 313  LEU 313  313  313  LEU LEU C . n 
B 2 314  ALA 314  314  314  ALA ALA C . n 
B 2 315  SER 315  315  315  SER SER C . n 
B 2 316  VAL 316  316  316  VAL VAL C . n 
B 2 317  ARG 317  317  317  ARG ARG C . n 
B 2 318  ILE 318  318  318  ILE ILE C . n 
B 2 319  TYR 319  319  319  TYR TYR C . n 
B 2 320  TYR 320  320  320  TYR TYR C . n 
B 2 321  GLN 321  321  321  GLN GLN C . n 
B 2 322  TYR 322  322  322  TYR TYR C . n 
B 2 323  ARG 323  323  323  ARG ARG C . n 
B 2 324  ARG 324  324  324  ARG ARG C . n 
B 2 325  VAL 325  325  325  VAL VAL C . n 
B 2 326  LYS 326  326  326  LYS LYS C . n 
B 2 327  PRO 327  327  327  PRO PRO C . n 
B 2 328  VAL 328  328  328  VAL VAL C . n 
B 2 329  THR 329  329  329  THR THR C . n 
B 2 330  ARG 330  330  330  ARG ARG C . n 
B 2 331  GLU 331  331  331  GLU GLU C . n 
B 2 332  ILE 332  332  332  ILE ILE C . n 
B 2 333  VAL 333  333  333  VAL VAL C . n 
B 2 334  ILE 334  334  334  ILE ILE C . n 
B 2 335  ARG 335  335  335  ARG ARG C . n 
B 2 336  ASP 336  336  336  ASP ASP C . n 
B 2 337  PRO 337  337  337  PRO PRO C . n 
B 2 338  TYR 338  338  338  TYR TYR C . n 
B 2 339  ALA 339  339  339  ALA ALA C . n 
B 2 340  LEU 340  340  340  LEU LEU C . n 
B 2 341  ARG 341  341  341  ARG ARG C . n 
B 2 342  PRO 342  342  342  PRO PRO C . n 
B 2 343  LEU 343  343  343  LEU LEU C . n 
B 2 344  ARG 344  344  344  ARG ARG C . n 
B 2 345  ARG 345  345  345  ARG ARG C . n 
B 2 346  LEU 346  346  346  LEU LEU C . n 
B 2 347  ILE 347  347  347  ILE ILE C . n 
B 2 348  ASP 348  348  348  ASP ASP C . n 
B 2 349  ALA 349  349  349  ALA ALA C . n 
B 2 350  TYR 350  350  350  TYR TYR C . n 
B 2 351  ALA 351  351  351  ALA ALA C . n 
B 2 352  PHE 352  352  352  PHE PHE C . n 
B 2 353  ARG 353  353  353  ARG ARG C . n 
B 2 354  ILE 354  354  354  ILE ILE C . n 
B 2 355  TYR 355  355  355  TYR TYR C . n 
B 2 356  GLY 356  356  356  GLY GLY C . n 
B 2 357  HIS 357  357  357  HIS HIS C . n 
B 2 358  TRP 358  358  358  TRP TRP C . n 
B 2 359  VAL 359  359  359  VAL VAL C . n 
B 2 360  LYS 360  360  360  LYS LYS C . n 
B 2 361  LYS 361  361  361  LYS LYS C . n 
B 2 362  GLY 362  362  362  GLY GLY C . n 
B 2 363  GLN 363  363  363  GLN GLN C . n 
B 2 364  GLN 364  364  364  GLN GLN C . n 
B 2 365  GLN 365  365  365  GLN GLN C . n 
B 2 366  ASN 366  366  366  ASN ASN C . n 
B 2 367  ARG 367  367  367  ARG ARG C . n 
B 2 368  ALA 368  368  368  ALA ALA C . n 
B 2 369  ALA 369  369  369  ALA ALA C . n 
B 2 370  LEU 370  370  370  LEU LEU C . n 
B 2 371  PHE 371  371  371  PHE PHE C . n 
B 2 372  GLU 372  372  372  GLU GLU C . n 
B 2 373  ASN 373  373  373  ASN ASN C . n 
B 2 374  THR 374  374  374  THR THR C . n 
B 2 375  PRO 375  375  375  PRO PRO C . n 
B 2 376  LYS 376  376  376  LYS LYS C . n 
B 2 377  ALA 377  377  377  ALA ALA C . n 
B 2 378  VAL 378  378  378  VAL VAL C . n 
B 2 379  LEU 379  379  379  LEU LEU C . n 
B 2 380  LEU 380  380  380  LEU LEU C . n 
B 2 381  SER 381  381  381  SER SER C . n 
B 2 382  LEU 382  382  382  LEU LEU C . n 
B 2 383  ALA 383  383  383  ALA ALA C . n 
B 2 384  GLU 384  384  ?    ?   ?   C . n 
B 2 385  GLU 385  385  ?    ?   ?   C . n 
B 2 386  ASP 386  386  ?    ?   ?   C . n 
B 2 387  TYR 387  387  ?    ?   ?   C . n 
C 3 1    ASP 1    -18  ?    ?   ?   D . n 
C 3 2    TYR 2    -17  ?    ?   ?   D . n 
C 3 3    LYS 3    -16  ?    ?   ?   D . n 
C 3 4    ASP 4    -15  ?    ?   ?   D . n 
C 3 5    ASP 5    -14  ?    ?   ?   D . n 
C 3 6    ASP 6    -13  ?    ?   ?   D . n 
C 3 7    ASP 7    -12  ?    ?   ?   D . n 
C 3 8    LYS 8    -11  ?    ?   ?   D . n 
C 3 9    SER 9    -10  ?    ?   ?   D . n 
C 3 10   GLY 10   -9   ?    ?   ?   D . n 
C 3 11   PRO 11   -8   ?    ?   ?   D . n 
C 3 12   ASP 12   -7   ?    ?   ?   D . n 
C 3 13   GLU 13   -6   ?    ?   ?   D . n 
C 3 14   VAL 14   -5   ?    ?   ?   D . n 
C 3 15   ASP 15   -4   ?    ?   ?   D . n 
C 3 16   ALA 16   -3   ?    ?   ?   D . n 
C 3 17   SER 17   -2   ?    ?   ?   D . n 
C 3 18   GLY 18   -1   ?    ?   ?   D . n 
C 3 19   ARG 19   0    ?    ?   ?   D . n 
C 3 20   MET 20   1    ?    ?   ?   D . n 
C 3 21   ALA 21   2    ?    ?   ?   D . n 
C 3 22   ASP 22   3    ?    ?   ?   D . n 
C 3 23   GLN 23   4    4    GLN GLN D . n 
C 3 24   LEU 24   5    5    LEU LEU D . n 
C 3 25   THR 25   6    6    THR THR D . n 
C 3 26   GLU 26   7    7    GLU GLU D . n 
C 3 27   GLU 27   8    8    GLU GLU D . n 
C 3 28   GLN 28   9    9    GLN GLN D . n 
C 3 29   ILE 29   10   10   ILE ILE D . n 
C 3 30   ALA 30   11   11   ALA ALA D . n 
C 3 31   GLU 31   12   12   GLU GLU D . n 
C 3 32   PHE 32   13   13   PHE PHE D . n 
C 3 33   LYS 33   14   14   LYS LYS D . n 
C 3 34   GLU 34   15   15   GLU GLU D . n 
C 3 35   ALA 35   16   16   ALA ALA D . n 
C 3 36   PHE 36   17   17   PHE PHE D . n 
C 3 37   SER 37   18   18   SER SER D . n 
C 3 38   LEU 38   19   19   LEU LEU D . n 
C 3 39   PHE 39   20   20   PHE PHE D . n 
C 3 40   ASP 40   21   21   ASP ASP D . n 
C 3 41   LYS 41   22   22   LYS LYS D . n 
C 3 42   ASP 42   23   23   ASP ASP D . n 
C 3 43   GLY 43   24   24   GLY GLY D . n 
C 3 44   ASP 44   25   25   ASP ASP D . n 
C 3 45   GLY 45   26   26   GLY GLY D . n 
C 3 46   THR 46   27   27   THR THR D . n 
C 3 47   ILE 47   28   28   ILE ILE D . n 
C 3 48   THR 48   29   29   THR THR D . n 
C 3 49   THR 49   30   30   THR THR D . n 
C 3 50   LYS 50   31   31   LYS LYS D . n 
C 3 51   GLU 51   32   32   GLU GLU D . n 
C 3 52   LEU 52   33   33   LEU LEU D . n 
C 3 53   GLY 53   34   34   GLY GLY D . n 
C 3 54   THR 54   35   35   THR THR D . n 
C 3 55   VAL 55   36   36   VAL VAL D . n 
C 3 56   MET 56   37   37   MET MET D . n 
C 3 57   ARG 57   38   38   ARG ARG D . n 
C 3 58   SER 58   39   39   SER SER D . n 
C 3 59   LEU 59   40   40   LEU LEU D . n 
C 3 60   GLY 60   41   41   GLY GLY D . n 
C 3 61   GLN 61   42   42   GLN GLN D . n 
C 3 62   ASN 62   43   43   ASN ASN D . n 
C 3 63   PRO 63   44   44   PRO PRO D . n 
C 3 64   THR 64   45   45   THR THR D . n 
C 3 65   GLU 65   46   46   GLU GLU D . n 
C 3 66   ALA 66   47   47   ALA ALA D . n 
C 3 67   GLU 67   48   48   GLU GLU D . n 
C 3 68   LEU 68   49   49   LEU LEU D . n 
C 3 69   GLN 69   50   50   GLN GLN D . n 
C 3 70   ASP 70   51   51   ASP ASP D . n 
C 3 71   MET 71   52   52   MET MET D . n 
C 3 72   ILE 72   53   53   ILE ILE D . n 
C 3 73   ASN 73   54   54   ASN ASN D . n 
C 3 74   GLU 74   55   55   GLU GLU D . n 
C 3 75   VAL 75   56   56   VAL VAL D . n 
C 3 76   ASP 76   57   57   ASP ASP D . n 
C 3 77   ALA 77   58   58   ALA ALA D . n 
C 3 78   ASP 78   59   59   ASP ASP D . n 
C 3 79   GLY 79   60   60   GLY GLY D . n 
C 3 80   ASN 80   61   61   ASN ASN D . n 
C 3 81   GLY 81   62   62   GLY GLY D . n 
C 3 82   THR 82   63   63   THR THR D . n 
C 3 83   ILE 83   64   64   ILE ILE D . n 
C 3 84   ASP 84   65   65   ASP ASP D . n 
C 3 85   PHE 85   66   66   PHE PHE D . n 
C 3 86   PRO 86   67   67   PRO PRO D . n 
C 3 87   GLU 87   68   68   GLU GLU D . n 
C 3 88   PHE 88   69   69   PHE PHE D . n 
C 3 89   LEU 89   70   70   LEU LEU D . n 
C 3 90   THR 90   71   71   THR THR D . n 
C 3 91   MET 91   72   72   MET MET D . n 
C 3 92   MET 92   73   73   MET MET D . n 
C 3 93   ALA 93   74   74   ALA ALA D . n 
C 3 94   ARG 94   75   75   ARG ARG D . n 
C 3 95   LYS 95   76   76   LYS LYS D . n 
C 3 96   MET 96   77   77   MET MET D . n 
C 3 97   LYS 97   78   78   LYS LYS D . n 
C 3 98   ASP 98   79   79   ASP ASP D . n 
C 3 99   THR 99   80   80   THR THR D . n 
C 3 100  ASP 100  81   81   ASP ASP D . n 
C 3 101  SER 101  82   82   SER SER D . n 
C 3 102  GLU 102  83   83   GLU GLU D . n 
C 3 103  GLU 103  84   84   GLU GLU D . n 
C 3 104  GLU 104  85   85   GLU GLU D . n 
C 3 105  ILE 105  86   86   ILE ILE D . n 
C 3 106  ARG 106  87   87   ARG ARG D . n 
C 3 107  GLU 107  88   88   GLU GLU D . n 
C 3 108  ALA 108  89   89   ALA ALA D . n 
C 3 109  PHE 109  90   90   PHE PHE D . n 
C 3 110  ARG 110  91   91   ARG ARG D . n 
C 3 111  VAL 111  92   92   VAL VAL D . n 
C 3 112  PHE 112  93   93   PHE PHE D . n 
C 3 113  ASP 113  94   94   ASP ASP D . n 
C 3 114  LYS 114  95   95   LYS LYS D . n 
C 3 115  ASP 115  96   96   ASP ASP D . n 
C 3 116  GLY 116  97   97   GLY GLY D . n 
C 3 117  ASN 117  98   98   ASN ASN D . n 
C 3 118  GLY 118  99   99   GLY GLY D . n 
C 3 119  TYR 119  100  100  TYR TYR D . n 
C 3 120  ILE 120  101  ?    ?   ?   D . n 
C 3 121  SER 121  102  ?    ?   ?   D . n 
C 3 122  ALA 122  103  ?    ?   ?   D . n 
C 3 123  ALA 123  104  ?    ?   ?   D . n 
C 3 124  GLU 124  105  ?    ?   ?   D . n 
C 3 125  LEU 125  106  ?    ?   ?   D . n 
C 3 126  ARG 126  107  ?    ?   ?   D . n 
C 3 127  HIS 127  108  ?    ?   ?   D . n 
C 3 128  VAL 128  109  ?    ?   ?   D . n 
C 3 129  MET 129  110  ?    ?   ?   D . n 
C 3 130  THR 130  111  ?    ?   ?   D . n 
C 3 131  ASN 131  112  ?    ?   ?   D . n 
C 3 132  LEU 132  113  ?    ?   ?   D . n 
C 3 133  GLY 133  114  ?    ?   ?   D . n 
C 3 134  GLU 134  115  ?    ?   ?   D . n 
C 3 135  LYS 135  116  ?    ?   ?   D . n 
C 3 136  LEU 136  117  ?    ?   ?   D . n 
C 3 137  THR 137  118  ?    ?   ?   D . n 
C 3 138  ASP 138  119  ?    ?   ?   D . n 
C 3 139  GLU 139  120  ?    ?   ?   D . n 
C 3 140  GLU 140  121  ?    ?   ?   D . n 
C 3 141  VAL 141  122  ?    ?   ?   D . n 
C 3 142  ASP 142  123  ?    ?   ?   D . n 
C 3 143  GLU 143  124  ?    ?   ?   D . n 
C 3 144  MET 144  125  ?    ?   ?   D . n 
C 3 145  ILE 145  126  ?    ?   ?   D . n 
C 3 146  ARG 146  127  ?    ?   ?   D . n 
C 3 147  GLU 147  128  ?    ?   ?   D . n 
C 3 148  ALA 148  129  ?    ?   ?   D . n 
C 3 149  ASP 149  130  ?    ?   ?   D . n 
C 3 150  ILE 150  131  ?    ?   ?   D . n 
C 3 151  ASP 151  132  ?    ?   ?   D . n 
C 3 152  GLY 152  133  ?    ?   ?   D . n 
C 3 153  ASP 153  134  ?    ?   ?   D . n 
C 3 154  GLY 154  135  ?    ?   ?   D . n 
C 3 155  GLN 155  136  ?    ?   ?   D . n 
C 3 156  VAL 156  137  ?    ?   ?   D . n 
C 3 157  ASN 157  138  ?    ?   ?   D . n 
C 3 158  TYR 158  139  ?    ?   ?   D . n 
C 3 159  GLU 159  140  ?    ?   ?   D . n 
C 3 160  GLU 160  141  ?    ?   ?   D . n 
C 3 161  PHE 161  142  ?    ?   ?   D . n 
C 3 162  VAL 162  143  ?    ?   ?   D . n 
C 3 163  GLN 163  144  ?    ?   ?   D . n 
C 3 164  MET 164  145  ?    ?   ?   D . n 
C 3 165  MET 165  146  ?    ?   ?   D . n 
C 3 166  THR 166  147  ?    ?   ?   D . n 
C 3 167  ALA 167  148  ?    ?   ?   D . n 
C 3 168  LYS 168  149  ?    ?   ?   D . n 
# 
_pdbx_nonpoly_scheme.asym_id         D 
_pdbx_nonpoly_scheme.entity_id       4 
_pdbx_nonpoly_scheme.mon_id          ATP 
_pdbx_nonpoly_scheme.ndb_seq_num     1 
_pdbx_nonpoly_scheme.pdb_seq_num     401 
_pdbx_nonpoly_scheme.auth_seq_num    401 
_pdbx_nonpoly_scheme.pdb_mon_id      ATP 
_pdbx_nonpoly_scheme.auth_mon_id     ATP 
_pdbx_nonpoly_scheme.pdb_strand_id   C 
_pdbx_nonpoly_scheme.pdb_ins_code    . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1   1 Y 1 A TYR 37   ? CG  ? A TYR 37   CG  
2   1 Y 1 A TYR 37   ? CD1 ? A TYR 37   CD1 
3   1 Y 1 A TYR 37   ? CD2 ? A TYR 37   CD2 
4   1 Y 1 A TYR 37   ? CE1 ? A TYR 37   CE1 
5   1 Y 1 A TYR 37   ? CE2 ? A TYR 37   CE2 
6   1 Y 1 A TYR 37   ? CZ  ? A TYR 37   CZ  
7   1 Y 1 A TYR 37   ? OH  ? A TYR 37   OH  
8   1 Y 1 A SEP 111  ? OG  ? A SEP 111  OG  
9   1 Y 1 A SEP 111  ? P   ? A SEP 111  P   
10  1 Y 1 A SEP 111  ? O1P ? A SEP 111  O1P 
11  1 Y 1 A SEP 111  ? O2P ? A SEP 111  O2P 
12  1 Y 1 A SEP 111  ? O3P ? A SEP 111  O3P 
13  1 Y 1 A SEP 201  ? OG  ? A SEP 201  OG  
14  1 Y 1 A SEP 201  ? P   ? A SEP 201  P   
15  1 Y 1 A SEP 201  ? O1P ? A SEP 201  O1P 
16  1 Y 1 A SEP 201  ? O2P ? A SEP 201  O2P 
17  1 Y 1 A SEP 201  ? O3P ? A SEP 201  O3P 
18  1 Y 1 A SEP 240  ? OG  ? A SEP 240  OG  
19  1 Y 1 A SEP 240  ? P   ? A SEP 240  P   
20  1 Y 1 A SEP 240  ? O1P ? A SEP 240  O1P 
21  1 Y 1 A SEP 240  ? O2P ? A SEP 240  O2P 
22  1 Y 1 A SEP 240  ? O3P ? A SEP 240  O3P 
23  1 Y 1 A ASP 437  ? CG  ? A ASP 437  CG  
24  1 Y 1 A ASP 437  ? OD1 ? A ASP 437  OD1 
25  1 Y 1 A ASP 437  ? OD2 ? A ASP 437  OD2 
26  1 Y 1 A SEP 480  ? OG  ? A SEP 480  OG  
27  1 Y 1 A SEP 480  ? P   ? A SEP 480  P   
28  1 Y 1 A SEP 480  ? O1P ? A SEP 480  O1P 
29  1 Y 1 A SEP 480  ? O2P ? A SEP 480  O2P 
30  1 Y 1 A SEP 480  ? O3P ? A SEP 480  O3P 
31  1 Y 1 A ASP 574  ? CG  ? A ASP 574  CG  
32  1 Y 1 A ASP 574  ? OD1 ? A ASP 574  OD1 
33  1 Y 1 A ASP 574  ? OD2 ? A ASP 574  OD2 
34  1 Y 1 A GLU 606  ? CG  ? A GLU 606  CG  
35  1 Y 1 A GLU 606  ? CD  ? A GLU 606  CD  
36  1 Y 1 A GLU 606  ? OE1 ? A GLU 606  OE1 
37  1 Y 1 A GLU 606  ? OE2 ? A GLU 606  OE2 
38  1 Y 1 A GLN 777  ? CG  ? A GLN 777  CG  
39  1 Y 1 A GLN 777  ? CD  ? A GLN 777  CD  
40  1 Y 1 A GLN 777  ? OE1 ? A GLN 777  OE1 
41  1 Y 1 A GLN 777  ? NE2 ? A GLN 777  NE2 
42  1 Y 1 A GLU 778  ? CG  ? A GLU 778  CG  
43  1 Y 1 A GLU 778  ? CD  ? A GLU 778  CD  
44  1 Y 1 A GLU 778  ? OE1 ? A GLU 778  OE1 
45  1 Y 1 A GLU 778  ? OE2 ? A GLU 778  OE2 
46  1 Y 1 A TPO 855  ? CG2 ? A TPO 855  CG2 
47  1 Y 1 A TPO 855  ? OG1 ? A TPO 855  OG1 
48  1 Y 1 A TPO 855  ? P   ? A TPO 855  P   
49  1 Y 1 A TPO 855  ? O1P ? A TPO 855  O1P 
50  1 Y 1 A TPO 855  ? O2P ? A TPO 855  O2P 
51  1 Y 1 A TPO 855  ? O3P ? A TPO 855  O3P 
52  1 Y 1 A LEU 858  ? CG  ? A LEU 858  CG  
53  1 Y 1 A LEU 858  ? CD1 ? A LEU 858  CD1 
54  1 Y 1 A LEU 858  ? CD2 ? A LEU 858  CD2 
55  1 Y 1 A LYS 865  ? CG  ? A LYS 865  CG  
56  1 Y 1 A LYS 865  ? CD  ? A LYS 865  CD  
57  1 Y 1 A LYS 865  ? CE  ? A LYS 865  CE  
58  1 Y 1 A LYS 865  ? NZ  ? A LYS 865  NZ  
59  1 Y 1 A ARG 1057 ? CG  ? A ARG 1057 CG  
60  1 Y 1 A ARG 1057 ? CD  ? A ARG 1057 CD  
61  1 Y 1 A ARG 1057 ? NE  ? A ARG 1057 NE  
62  1 Y 1 A ARG 1057 ? CZ  ? A ARG 1057 CZ  
63  1 Y 1 A ARG 1057 ? NH1 ? A ARG 1057 NH1 
64  1 Y 1 A ARG 1057 ? NH2 ? A ARG 1057 NH2 
65  1 Y 1 A PHE 1107 ? CG  ? A PHE 1107 CG  
66  1 Y 1 A PHE 1107 ? CD1 ? A PHE 1107 CD1 
67  1 Y 1 A PHE 1107 ? CD2 ? A PHE 1107 CD2 
68  1 Y 1 A PHE 1107 ? CE1 ? A PHE 1107 CE1 
69  1 Y 1 A PHE 1107 ? CE2 ? A PHE 1107 CE2 
70  1 Y 1 A PHE 1107 ? CZ  ? A PHE 1107 CZ  
71  1 Y 1 A LEU 1132 ? CG  ? A LEU 1132 CG  
72  1 Y 1 A LEU 1132 ? CD1 ? A LEU 1132 CD1 
73  1 Y 1 A LEU 1132 ? CD2 ? A LEU 1132 CD2 
74  1 Y 1 A MET 1136 ? CG  ? A MET 1136 CG  
75  1 Y 1 A MET 1136 ? SD  ? A MET 1136 SD  
76  1 Y 1 A MET 1136 ? CE  ? A MET 1136 CE  
77  1 Y 1 A HIS 1143 ? CG  ? A HIS 1143 CG  
78  1 Y 1 A HIS 1143 ? ND1 ? A HIS 1143 ND1 
79  1 Y 1 A HIS 1143 ? CD2 ? A HIS 1143 CD2 
80  1 Y 1 A HIS 1143 ? CE1 ? A HIS 1143 CE1 
81  1 Y 1 A HIS 1143 ? NE2 ? A HIS 1143 NE2 
82  1 Y 1 A SEP 1194 ? OG  ? A SEP 1194 OG  
83  1 Y 1 A SEP 1194 ? P   ? A SEP 1194 P   
84  1 Y 1 A SEP 1194 ? O1P ? A SEP 1194 O1P 
85  1 Y 1 A SEP 1194 ? O2P ? A SEP 1194 O2P 
86  1 Y 1 A SEP 1194 ? O3P ? A SEP 1194 O3P 
87  1 Y 1 A ARG 1196 ? CG  ? A ARG 1196 CG  
88  1 Y 1 A ARG 1196 ? CD  ? A ARG 1196 CD  
89  1 Y 1 A ARG 1196 ? NE  ? A ARG 1196 NE  
90  1 Y 1 A ARG 1196 ? CZ  ? A ARG 1196 CZ  
91  1 Y 1 A ARG 1196 ? NH1 ? A ARG 1196 NH1 
92  1 Y 1 A ARG 1196 ? NH2 ? A ARG 1196 NH2 
93  1 Y 1 A PHE 1197 ? CG  ? A PHE 1197 CG  
94  1 Y 1 A PHE 1197 ? CD1 ? A PHE 1197 CD1 
95  1 Y 1 A PHE 1197 ? CD2 ? A PHE 1197 CD2 
96  1 Y 1 A PHE 1197 ? CE1 ? A PHE 1197 CE1 
97  1 Y 1 A PHE 1197 ? CE2 ? A PHE 1197 CE2 
98  1 Y 1 A PHE 1197 ? CZ  ? A PHE 1197 CZ  
99  1 Y 1 C GLN 14   ? CG  ? B GLN 14   CG  
100 1 Y 1 C GLN 14   ? CD  ? B GLN 14   CD  
101 1 Y 1 C GLN 14   ? OE1 ? B GLN 14   OE1 
102 1 Y 1 C GLN 14   ? NE2 ? B GLN 14   NE2 
103 1 Y 1 C PHE 16   ? CG  ? B PHE 16   CG  
104 1 Y 1 C PHE 16   ? CD1 ? B PHE 16   CD1 
105 1 Y 1 C PHE 16   ? CD2 ? B PHE 16   CD2 
106 1 Y 1 C PHE 16   ? CE1 ? B PHE 16   CE1 
107 1 Y 1 C PHE 16   ? CE2 ? B PHE 16   CE2 
108 1 Y 1 C PHE 16   ? CZ  ? B PHE 16   CZ  
109 1 Y 1 C TYR 17   ? CG  ? B TYR 17   CG  
110 1 Y 1 C TYR 17   ? CD1 ? B TYR 17   CD1 
111 1 Y 1 C TYR 17   ? CD2 ? B TYR 17   CD2 
112 1 Y 1 C TYR 17   ? CE1 ? B TYR 17   CE1 
113 1 Y 1 C TYR 17   ? CE2 ? B TYR 17   CE2 
114 1 Y 1 C TYR 17   ? CZ  ? B TYR 17   CZ  
115 1 Y 1 C TYR 17   ? OH  ? B TYR 17   OH  
116 1 Y 1 C GLU 18   ? CG  ? B GLU 18   CG  
117 1 Y 1 C GLU 18   ? CD  ? B GLU 18   CD  
118 1 Y 1 C GLU 18   ? OE1 ? B GLU 18   OE1 
119 1 Y 1 C GLU 18   ? OE2 ? B GLU 18   OE2 
120 1 Y 1 C TYR 20   ? CG  ? B TYR 20   CG  
121 1 Y 1 C TYR 20   ? CD1 ? B TYR 20   CD1 
122 1 Y 1 C TYR 20   ? CD2 ? B TYR 20   CD2 
123 1 Y 1 C TYR 20   ? CE1 ? B TYR 20   CE1 
124 1 Y 1 C TYR 20   ? CE2 ? B TYR 20   CE2 
125 1 Y 1 C TYR 20   ? CZ  ? B TYR 20   CZ  
126 1 Y 1 C TYR 20   ? OH  ? B TYR 20   OH  
127 1 Y 1 C GLU 24   ? CG  ? B GLU 24   CG  
128 1 Y 1 C GLU 24   ? CD  ? B GLU 24   CD  
129 1 Y 1 C GLU 24   ? OE1 ? B GLU 24   OE1 
130 1 Y 1 C GLU 24   ? OE2 ? B GLU 24   OE2 
131 1 Y 1 C ARG 28   ? CG  ? B ARG 28   CG  
132 1 Y 1 C ARG 28   ? CD  ? B ARG 28   CD  
133 1 Y 1 C ARG 28   ? NE  ? B ARG 28   NE  
134 1 Y 1 C ARG 28   ? CZ  ? B ARG 28   CZ  
135 1 Y 1 C ARG 28   ? NH1 ? B ARG 28   NH1 
136 1 Y 1 C ARG 28   ? NH2 ? B ARG 28   NH2 
137 1 Y 1 C ARG 36   ? CG  ? B ARG 36   CG  
138 1 Y 1 C ARG 36   ? CD  ? B ARG 36   CD  
139 1 Y 1 C ARG 36   ? NE  ? B ARG 36   NE  
140 1 Y 1 C ARG 36   ? CZ  ? B ARG 36   CZ  
141 1 Y 1 C ARG 36   ? NH1 ? B ARG 36   NH1 
142 1 Y 1 C ARG 36   ? NH2 ? B ARG 36   NH2 
143 1 Y 1 C GLN 44   ? CG  ? B GLN 44   CG  
144 1 Y 1 C GLN 44   ? CD  ? B GLN 44   CD  
145 1 Y 1 C GLN 44   ? OE1 ? B GLN 44   OE1 
146 1 Y 1 C GLN 44   ? NE2 ? B GLN 44   NE2 
147 1 Y 1 C GLU 45   ? CG  ? B GLU 45   CG  
148 1 Y 1 C GLU 45   ? CD  ? B GLU 45   CD  
149 1 Y 1 C GLU 45   ? OE1 ? B GLU 45   OE1 
150 1 Y 1 C GLU 45   ? OE2 ? B GLU 45   OE2 
151 1 Y 1 C VAL 64   ? CG1 ? B VAL 64   CG1 
152 1 Y 1 C VAL 64   ? CG2 ? B VAL 64   CG2 
153 1 Y 1 C ARG 68   ? CG  ? B ARG 68   CG  
154 1 Y 1 C ARG 68   ? CD  ? B ARG 68   CD  
155 1 Y 1 C ARG 68   ? NE  ? B ARG 68   NE  
156 1 Y 1 C ARG 68   ? CZ  ? B ARG 68   CZ  
157 1 Y 1 C ARG 68   ? NH1 ? B ARG 68   NH1 
158 1 Y 1 C ARG 68   ? NH2 ? B ARG 68   NH2 
159 1 Y 1 C GLU 69   ? CG  ? B GLU 69   CG  
160 1 Y 1 C GLU 69   ? CD  ? B GLU 69   CD  
161 1 Y 1 C GLU 69   ? OE1 ? B GLU 69   OE1 
162 1 Y 1 C GLU 69   ? OE2 ? B GLU 69   OE2 
163 1 Y 1 C LYS 73   ? CG  ? B LYS 73   CG  
164 1 Y 1 C LYS 73   ? CD  ? B LYS 73   CD  
165 1 Y 1 C LYS 73   ? CE  ? B LYS 73   CE  
166 1 Y 1 C LYS 73   ? NZ  ? B LYS 73   NZ  
167 1 Y 1 C GLU 74   ? CG  ? B GLU 74   CG  
168 1 Y 1 C GLU 74   ? CD  ? B GLU 74   CD  
169 1 Y 1 C GLU 74   ? OE1 ? B GLU 74   OE1 
170 1 Y 1 C GLU 74   ? OE2 ? B GLU 74   OE2 
171 1 Y 1 C ARG 79   ? CG  ? B ARG 79   CG  
172 1 Y 1 C ARG 79   ? CD  ? B ARG 79   CD  
173 1 Y 1 C ARG 79   ? NE  ? B ARG 79   NE  
174 1 Y 1 C ARG 79   ? CZ  ? B ARG 79   CZ  
175 1 Y 1 C ARG 79   ? NH1 ? B ARG 79   NH1 
176 1 Y 1 C ARG 79   ? NH2 ? B ARG 79   NH2 
177 1 Y 1 C GLN 89   ? CG  ? B GLN 89   CG  
178 1 Y 1 C GLN 89   ? CD  ? B GLN 89   CD  
179 1 Y 1 C GLN 89   ? OE1 ? B GLN 89   OE1 
180 1 Y 1 C GLN 89   ? NE2 ? B GLN 89   NE2 
181 1 Y 1 C LYS 91   ? CG  ? B LYS 91   CG  
182 1 Y 1 C LYS 91   ? CD  ? B LYS 91   CD  
183 1 Y 1 C LYS 91   ? CE  ? B LYS 91   CE  
184 1 Y 1 C LYS 91   ? NZ  ? B LYS 91   NZ  
185 1 Y 1 C ASP 92   ? CG  ? B ASP 92   CG  
186 1 Y 1 C ASP 92   ? OD1 ? B ASP 92   OD1 
187 1 Y 1 C ASP 92   ? OD2 ? B ASP 92   OD2 
188 1 Y 1 C GLU 95   ? CG  ? B GLU 95   CG  
189 1 Y 1 C GLU 95   ? CD  ? B GLU 95   CD  
190 1 Y 1 C GLU 95   ? OE1 ? B GLU 95   OE1 
191 1 Y 1 C GLU 95   ? OE2 ? B GLU 95   OE2 
192 1 Y 1 C LEU 106  ? CG  ? B LEU 106  CG  
193 1 Y 1 C LEU 106  ? CD1 ? B LEU 106  CD1 
194 1 Y 1 C LEU 106  ? CD2 ? B LEU 106  CD2 
195 1 Y 1 C LYS 108  ? CG  ? B LYS 108  CG  
196 1 Y 1 C LYS 108  ? CD  ? B LYS 108  CD  
197 1 Y 1 C LYS 108  ? CE  ? B LYS 108  CE  
198 1 Y 1 C LYS 108  ? NZ  ? B LYS 108  NZ  
199 1 Y 1 C ARG 109  ? CG  ? B ARG 109  CG  
200 1 Y 1 C ARG 109  ? CD  ? B ARG 109  CD  
201 1 Y 1 C ARG 109  ? NE  ? B ARG 109  NE  
202 1 Y 1 C ARG 109  ? CZ  ? B ARG 109  CZ  
203 1 Y 1 C ARG 109  ? NH1 ? B ARG 109  NH1 
204 1 Y 1 C ARG 109  ? NH2 ? B ARG 109  NH2 
205 1 Y 1 C GLU 111  ? CG  ? B GLU 111  CG  
206 1 Y 1 C GLU 111  ? CD  ? B GLU 111  CD  
207 1 Y 1 C GLU 111  ? OE1 ? B GLU 111  OE1 
208 1 Y 1 C GLU 111  ? OE2 ? B GLU 111  OE2 
209 1 Y 1 C LYS 125  ? CG  ? B LYS 125  CG  
210 1 Y 1 C LYS 125  ? CD  ? B LYS 125  CD  
211 1 Y 1 C LYS 125  ? CE  ? B LYS 125  CE  
212 1 Y 1 C LYS 125  ? NZ  ? B LYS 125  NZ  
213 1 Y 1 C GLU 126  ? CG  ? B GLU 126  CG  
214 1 Y 1 C GLU 126  ? CD  ? B GLU 126  CD  
215 1 Y 1 C GLU 126  ? OE1 ? B GLU 126  OE1 
216 1 Y 1 C GLU 126  ? OE2 ? B GLU 126  OE2 
217 1 Y 1 C GLU 136  ? CG  ? B GLU 136  CG  
218 1 Y 1 C GLU 136  ? CD  ? B GLU 136  CD  
219 1 Y 1 C GLU 136  ? OE1 ? B GLU 136  OE1 
220 1 Y 1 C GLU 136  ? OE2 ? B GLU 136  OE2 
221 1 Y 1 C LYS 152  ? CG  ? B LYS 152  CG  
222 1 Y 1 C LYS 152  ? CD  ? B LYS 152  CD  
223 1 Y 1 C LYS 152  ? CE  ? B LYS 152  CE  
224 1 Y 1 C LYS 152  ? NZ  ? B LYS 152  NZ  
225 1 Y 1 C ASN 161  ? CG  ? B ASN 161  CG  
226 1 Y 1 C ASN 161  ? OD1 ? B ASN 161  OD1 
227 1 Y 1 C ASN 161  ? ND2 ? B ASN 161  ND2 
228 1 Y 1 C GLU 194  ? CG  ? B GLU 194  CG  
229 1 Y 1 C GLU 194  ? CD  ? B GLU 194  CD  
230 1 Y 1 C GLU 194  ? OE1 ? B GLU 194  OE1 
231 1 Y 1 C GLU 194  ? OE2 ? B GLU 194  OE2 
232 1 Y 1 C GLU 197  ? CG  ? B GLU 197  CG  
233 1 Y 1 C GLU 197  ? CD  ? B GLU 197  CD  
234 1 Y 1 C GLU 197  ? OE1 ? B GLU 197  OE1 
235 1 Y 1 C GLU 197  ? OE2 ? B GLU 197  OE2 
236 1 Y 1 C MET 200  ? CG  ? B MET 200  CG  
237 1 Y 1 C MET 200  ? SD  ? B MET 200  SD  
238 1 Y 1 C MET 200  ? CE  ? B MET 200  CE  
239 1 Y 1 C HIS 204  ? CG  ? B HIS 204  CG  
240 1 Y 1 C HIS 204  ? ND1 ? B HIS 204  ND1 
241 1 Y 1 C HIS 204  ? CD2 ? B HIS 204  CD2 
242 1 Y 1 C HIS 204  ? CE1 ? B HIS 204  CE1 
243 1 Y 1 C HIS 204  ? NE2 ? B HIS 204  NE2 
244 1 Y 1 C MET 220  ? CG  ? B MET 220  CG  
245 1 Y 1 C MET 220  ? SD  ? B MET 220  SD  
246 1 Y 1 C MET 220  ? CE  ? B MET 220  CE  
247 1 Y 1 C LEU 224  ? CG  ? B LEU 224  CG  
248 1 Y 1 C LEU 224  ? CD1 ? B LEU 224  CD1 
249 1 Y 1 C LEU 224  ? CD2 ? B LEU 224  CD2 
250 1 Y 1 C PHE 230  ? CG  ? B PHE 230  CG  
251 1 Y 1 C PHE 230  ? CD1 ? B PHE 230  CD1 
252 1 Y 1 C PHE 230  ? CD2 ? B PHE 230  CD2 
253 1 Y 1 C PHE 230  ? CE1 ? B PHE 230  CE1 
254 1 Y 1 C PHE 230  ? CE2 ? B PHE 230  CE2 
255 1 Y 1 C PHE 230  ? CZ  ? B PHE 230  CZ  
256 1 Y 1 C ARG 233  ? CG  ? B ARG 233  CG  
257 1 Y 1 C ARG 233  ? CD  ? B ARG 233  CD  
258 1 Y 1 C ARG 233  ? NE  ? B ARG 233  NE  
259 1 Y 1 C ARG 233  ? CZ  ? B ARG 233  CZ  
260 1 Y 1 C ARG 233  ? NH1 ? B ARG 233  NH1 
261 1 Y 1 C ARG 233  ? NH2 ? B ARG 233  NH2 
262 1 Y 1 C LYS 234  ? CG  ? B LYS 234  CG  
263 1 Y 1 C LYS 234  ? CD  ? B LYS 234  CD  
264 1 Y 1 C LYS 234  ? CE  ? B LYS 234  CE  
265 1 Y 1 C LYS 234  ? NZ  ? B LYS 234  NZ  
266 1 Y 1 C MET 236  ? CG  ? B MET 236  CG  
267 1 Y 1 C MET 236  ? SD  ? B MET 236  SD  
268 1 Y 1 C MET 236  ? CE  ? B MET 236  CE  
269 1 Y 1 C LEU 237  ? CG  ? B LEU 237  CG  
270 1 Y 1 C LEU 237  ? CD1 ? B LEU 237  CD1 
271 1 Y 1 C LEU 237  ? CD2 ? B LEU 237  CD2 
272 1 Y 1 C ARG 240  ? CG  ? B ARG 240  CG  
273 1 Y 1 C ARG 240  ? CD  ? B ARG 240  CD  
274 1 Y 1 C ARG 240  ? NE  ? B ARG 240  NE  
275 1 Y 1 C ARG 240  ? CZ  ? B ARG 240  CZ  
276 1 Y 1 C ARG 240  ? NH1 ? B ARG 240  NH1 
277 1 Y 1 C ARG 240  ? NH2 ? B ARG 240  NH2 
278 1 Y 1 C MET 241  ? CG  ? B MET 241  CG  
279 1 Y 1 C MET 241  ? SD  ? B MET 241  SD  
280 1 Y 1 C MET 241  ? CE  ? B MET 241  CE  
281 1 Y 1 C MET 243  ? CG  ? B MET 243  CG  
282 1 Y 1 C MET 243  ? SD  ? B MET 243  SD  
283 1 Y 1 C MET 243  ? CE  ? B MET 243  CE  
284 1 Y 1 C GLN 248  ? CG  ? B GLN 248  CG  
285 1 Y 1 C GLN 248  ? CD  ? B GLN 248  CD  
286 1 Y 1 C GLN 248  ? OE1 ? B GLN 248  OE1 
287 1 Y 1 C GLN 248  ? NE2 ? B GLN 248  NE2 
288 1 Y 1 C GLU 253  ? CG  ? B GLU 253  CG  
289 1 Y 1 C GLU 253  ? CD  ? B GLU 253  CD  
290 1 Y 1 C GLU 253  ? OE1 ? B GLU 253  OE1 
291 1 Y 1 C GLU 253  ? OE2 ? B GLU 253  OE2 
292 1 Y 1 C GLN 272  ? CG  ? B GLN 272  CG  
293 1 Y 1 C GLN 272  ? CD  ? B GLN 272  CD  
294 1 Y 1 C GLN 272  ? OE1 ? B GLN 272  OE1 
295 1 Y 1 C GLN 272  ? NE2 ? B GLN 272  NE2 
296 1 Y 1 C GLN 274  ? CG  ? B GLN 274  CG  
297 1 Y 1 C GLN 274  ? CD  ? B GLN 274  CD  
298 1 Y 1 C GLN 274  ? OE1 ? B GLN 274  OE1 
299 1 Y 1 C GLN 274  ? NE2 ? B GLN 274  NE2 
300 1 Y 1 C ASN 275  ? CG  ? B ASN 275  CG  
301 1 Y 1 C ASN 275  ? OD1 ? B ASN 275  OD1 
302 1 Y 1 C ASN 275  ? ND2 ? B ASN 275  ND2 
303 1 Y 1 C GLU 281  ? CG  ? B GLU 281  CG  
304 1 Y 1 C GLU 281  ? CD  ? B GLU 281  CD  
305 1 Y 1 C GLU 281  ? OE1 ? B GLU 281  OE1 
306 1 Y 1 C GLU 281  ? OE2 ? B GLU 281  OE2 
307 1 Y 1 C VAL 307  ? CG1 ? B VAL 307  CG1 
308 1 Y 1 C VAL 307  ? CG2 ? B VAL 307  CG2 
309 1 Y 1 C ARG 330  ? CG  ? B ARG 330  CG  
310 1 Y 1 C ARG 330  ? CD  ? B ARG 330  CD  
311 1 Y 1 C ARG 330  ? NE  ? B ARG 330  NE  
312 1 Y 1 C ARG 330  ? CZ  ? B ARG 330  CZ  
313 1 Y 1 C ARG 330  ? NH1 ? B ARG 330  NH1 
314 1 Y 1 C ARG 330  ? NH2 ? B ARG 330  NH2 
315 1 Y 1 C GLU 331  ? CG  ? B GLU 331  CG  
316 1 Y 1 C GLU 331  ? CD  ? B GLU 331  CD  
317 1 Y 1 C GLU 331  ? OE1 ? B GLU 331  OE1 
318 1 Y 1 C GLU 331  ? OE2 ? B GLU 331  OE2 
319 1 Y 1 C TYR 338  ? CG  ? B TYR 338  CG  
320 1 Y 1 C TYR 338  ? CD1 ? B TYR 338  CD1 
321 1 Y 1 C TYR 338  ? CD2 ? B TYR 338  CD2 
322 1 Y 1 C TYR 338  ? CE1 ? B TYR 338  CE1 
323 1 Y 1 C TYR 338  ? CE2 ? B TYR 338  CE2 
324 1 Y 1 C TYR 338  ? CZ  ? B TYR 338  CZ  
325 1 Y 1 C TYR 338  ? OH  ? B TYR 338  OH  
326 1 Y 1 C LEU 340  ? CG  ? B LEU 340  CG  
327 1 Y 1 C LEU 340  ? CD1 ? B LEU 340  CD1 
328 1 Y 1 C LEU 340  ? CD2 ? B LEU 340  CD2 
329 1 Y 1 C ARG 341  ? CG  ? B ARG 341  CG  
330 1 Y 1 C ARG 341  ? CD  ? B ARG 341  CD  
331 1 Y 1 C ARG 341  ? NE  ? B ARG 341  NE  
332 1 Y 1 C ARG 341  ? CZ  ? B ARG 341  CZ  
333 1 Y 1 C ARG 341  ? NH1 ? B ARG 341  NH1 
334 1 Y 1 C ARG 341  ? NH2 ? B ARG 341  NH2 
335 1 Y 1 C ARG 345  ? CG  ? B ARG 345  CG  
336 1 Y 1 C ARG 345  ? CD  ? B ARG 345  CD  
337 1 Y 1 C ARG 345  ? NE  ? B ARG 345  NE  
338 1 Y 1 C ARG 345  ? CZ  ? B ARG 345  CZ  
339 1 Y 1 C ARG 345  ? NH1 ? B ARG 345  NH1 
340 1 Y 1 C ARG 345  ? NH2 ? B ARG 345  NH2 
341 1 Y 1 C LEU 346  ? CG  ? B LEU 346  CG  
342 1 Y 1 C LEU 346  ? CD1 ? B LEU 346  CD1 
343 1 Y 1 C LEU 346  ? CD2 ? B LEU 346  CD2 
344 1 Y 1 C ASP 348  ? CG  ? B ASP 348  CG  
345 1 Y 1 C ASP 348  ? OD1 ? B ASP 348  OD1 
346 1 Y 1 C ASP 348  ? OD2 ? B ASP 348  OD2 
347 1 Y 1 C ARG 353  ? CG  ? B ARG 353  CG  
348 1 Y 1 C ARG 353  ? CD  ? B ARG 353  CD  
349 1 Y 1 C ARG 353  ? NE  ? B ARG 353  NE  
350 1 Y 1 C ARG 353  ? CZ  ? B ARG 353  CZ  
351 1 Y 1 C ARG 353  ? NH1 ? B ARG 353  NH1 
352 1 Y 1 C ARG 353  ? NH2 ? B ARG 353  NH2 
353 1 Y 1 C GLU 372  ? CG  ? B GLU 372  CG  
354 1 Y 1 C GLU 372  ? CD  ? B GLU 372  CD  
355 1 Y 1 C GLU 372  ? OE1 ? B GLU 372  OE1 
356 1 Y 1 C GLU 372  ? OE2 ? B GLU 372  OE2 
357 1 Y 1 D GLU 7    ? CG  ? C GLU 26   CG  
358 1 Y 1 D GLU 7    ? CD  ? C GLU 26   CD  
359 1 Y 1 D GLU 7    ? OE1 ? C GLU 26   OE1 
360 1 Y 1 D GLU 7    ? OE2 ? C GLU 26   OE2 
361 1 Y 1 D GLU 8    ? CG  ? C GLU 27   CG  
362 1 Y 1 D GLU 8    ? CD  ? C GLU 27   CD  
363 1 Y 1 D GLU 8    ? OE1 ? C GLU 27   OE1 
364 1 Y 1 D GLU 8    ? OE2 ? C GLU 27   OE2 
365 1 Y 1 D GLN 9    ? CG  ? C GLN 28   CG  
366 1 Y 1 D GLN 9    ? CD  ? C GLN 28   CD  
367 1 Y 1 D GLN 9    ? OE1 ? C GLN 28   OE1 
368 1 Y 1 D GLN 9    ? NE2 ? C GLN 28   NE2 
369 1 Y 1 D GLU 12   ? CG  ? C GLU 31   CG  
370 1 Y 1 D GLU 12   ? CD  ? C GLU 31   CD  
371 1 Y 1 D GLU 12   ? OE1 ? C GLU 31   OE1 
372 1 Y 1 D GLU 12   ? OE2 ? C GLU 31   OE2 
373 1 Y 1 D PHE 13   ? CG  ? C PHE 32   CG  
374 1 Y 1 D PHE 13   ? CD1 ? C PHE 32   CD1 
375 1 Y 1 D PHE 13   ? CD2 ? C PHE 32   CD2 
376 1 Y 1 D PHE 13   ? CE1 ? C PHE 32   CE1 
377 1 Y 1 D PHE 13   ? CE2 ? C PHE 32   CE2 
378 1 Y 1 D PHE 13   ? CZ  ? C PHE 32   CZ  
379 1 Y 1 D LYS 14   ? CG  ? C LYS 33   CG  
380 1 Y 1 D LYS 14   ? CD  ? C LYS 33   CD  
381 1 Y 1 D LYS 14   ? CE  ? C LYS 33   CE  
382 1 Y 1 D LYS 14   ? NZ  ? C LYS 33   NZ  
383 1 Y 1 D GLU 15   ? CG  ? C GLU 34   CG  
384 1 Y 1 D GLU 15   ? CD  ? C GLU 34   CD  
385 1 Y 1 D GLU 15   ? OE1 ? C GLU 34   OE1 
386 1 Y 1 D GLU 15   ? OE2 ? C GLU 34   OE2 
387 1 Y 1 D PHE 17   ? CG  ? C PHE 36   CG  
388 1 Y 1 D PHE 17   ? CD1 ? C PHE 36   CD1 
389 1 Y 1 D PHE 17   ? CD2 ? C PHE 36   CD2 
390 1 Y 1 D PHE 17   ? CE1 ? C PHE 36   CE1 
391 1 Y 1 D PHE 17   ? CE2 ? C PHE 36   CE2 
392 1 Y 1 D PHE 17   ? CZ  ? C PHE 36   CZ  
393 1 Y 1 D PHE 20   ? CG  ? C PHE 39   CG  
394 1 Y 1 D PHE 20   ? CD1 ? C PHE 39   CD1 
395 1 Y 1 D PHE 20   ? CD2 ? C PHE 39   CD2 
396 1 Y 1 D PHE 20   ? CE1 ? C PHE 39   CE1 
397 1 Y 1 D PHE 20   ? CE2 ? C PHE 39   CE2 
398 1 Y 1 D PHE 20   ? CZ  ? C PHE 39   CZ  
399 1 Y 1 D LYS 31   ? CG  ? C LYS 50   CG  
400 1 Y 1 D LYS 31   ? CD  ? C LYS 50   CD  
401 1 Y 1 D LYS 31   ? CE  ? C LYS 50   CE  
402 1 Y 1 D LYS 31   ? NZ  ? C LYS 50   NZ  
403 1 Y 1 D GLU 32   ? CG  ? C GLU 51   CG  
404 1 Y 1 D GLU 32   ? CD  ? C GLU 51   CD  
405 1 Y 1 D GLU 32   ? OE1 ? C GLU 51   OE1 
406 1 Y 1 D GLU 32   ? OE2 ? C GLU 51   OE2 
407 1 Y 1 D MET 37   ? CG  ? C MET 56   CG  
408 1 Y 1 D MET 37   ? SD  ? C MET 56   SD  
409 1 Y 1 D MET 37   ? CE  ? C MET 56   CE  
410 1 Y 1 D ASN 43   ? CG  ? C ASN 62   CG  
411 1 Y 1 D ASN 43   ? OD1 ? C ASN 62   OD1 
412 1 Y 1 D ASN 43   ? ND2 ? C ASN 62   ND2 
413 1 Y 1 D THR 45   ? OG1 ? C THR 64   OG1 
414 1 Y 1 D THR 45   ? CG2 ? C THR 64   CG2 
415 1 Y 1 D GLU 46   ? CG  ? C GLU 65   CG  
416 1 Y 1 D GLU 46   ? CD  ? C GLU 65   CD  
417 1 Y 1 D GLU 46   ? OE1 ? C GLU 65   OE1 
418 1 Y 1 D GLU 46   ? OE2 ? C GLU 65   OE2 
419 1 Y 1 D GLU 48   ? CG  ? C GLU 67   CG  
420 1 Y 1 D GLU 48   ? CD  ? C GLU 67   CD  
421 1 Y 1 D GLU 48   ? OE1 ? C GLU 67   OE1 
422 1 Y 1 D GLU 48   ? OE2 ? C GLU 67   OE2 
423 1 Y 1 D LEU 49   ? CG  ? C LEU 68   CG  
424 1 Y 1 D LEU 49   ? CD1 ? C LEU 68   CD1 
425 1 Y 1 D LEU 49   ? CD2 ? C LEU 68   CD2 
426 1 Y 1 D MET 52   ? CG  ? C MET 71   CG  
427 1 Y 1 D MET 52   ? SD  ? C MET 71   SD  
428 1 Y 1 D MET 52   ? CE  ? C MET 71   CE  
429 1 Y 1 D PHE 66   ? CG  ? C PHE 85   CG  
430 1 Y 1 D PHE 66   ? CD1 ? C PHE 85   CD1 
431 1 Y 1 D PHE 66   ? CD2 ? C PHE 85   CD2 
432 1 Y 1 D PHE 66   ? CE1 ? C PHE 85   CE1 
433 1 Y 1 D PHE 66   ? CE2 ? C PHE 85   CE2 
434 1 Y 1 D PHE 66   ? CZ  ? C PHE 85   CZ  
435 1 Y 1 D GLU 68   ? CG  ? C GLU 87   CG  
436 1 Y 1 D GLU 68   ? CD  ? C GLU 87   CD  
437 1 Y 1 D GLU 68   ? OE1 ? C GLU 87   OE1 
438 1 Y 1 D GLU 68   ? OE2 ? C GLU 87   OE2 
439 1 Y 1 D MET 72   ? CG  ? C MET 91   CG  
440 1 Y 1 D MET 72   ? SD  ? C MET 91   SD  
441 1 Y 1 D MET 72   ? CE  ? C MET 91   CE  
442 1 Y 1 D MET 73   ? CG  ? C MET 92   CG  
443 1 Y 1 D MET 73   ? SD  ? C MET 92   SD  
444 1 Y 1 D MET 73   ? CE  ? C MET 92   CE  
445 1 Y 1 D LYS 76   ? CB  ? C LYS 95   CB  
446 1 Y 1 D LYS 76   ? CG  ? C LYS 95   CG  
447 1 Y 1 D LYS 76   ? CD  ? C LYS 95   CD  
448 1 Y 1 D LYS 76   ? CE  ? C LYS 95   CE  
449 1 Y 1 D LYS 76   ? NZ  ? C LYS 95   NZ  
450 1 Y 1 D MET 77   ? CG  ? C MET 96   CG  
451 1 Y 1 D MET 77   ? SD  ? C MET 96   SD  
452 1 Y 1 D MET 77   ? CE  ? C MET 96   CE  
453 1 Y 1 D LYS 78   ? CB  ? C LYS 97   CB  
454 1 Y 1 D LYS 78   ? CG  ? C LYS 97   CG  
455 1 Y 1 D LYS 78   ? CD  ? C LYS 97   CD  
456 1 Y 1 D LYS 78   ? CE  ? C LYS 97   CE  
457 1 Y 1 D LYS 78   ? NZ  ? C LYS 97   NZ  
458 1 Y 1 D GLU 88   ? CG  ? C GLU 107  CG  
459 1 Y 1 D GLU 88   ? CD  ? C GLU 107  CD  
460 1 Y 1 D GLU 88   ? OE1 ? C GLU 107  OE1 
461 1 Y 1 D GLU 88   ? OE2 ? C GLU 107  OE2 
462 1 Y 1 D ARG 91   ? CG  ? C ARG 110  CG  
463 1 Y 1 D ARG 91   ? CD  ? C ARG 110  CD  
464 1 Y 1 D ARG 91   ? NE  ? C ARG 110  NE  
465 1 Y 1 D ARG 91   ? CZ  ? C ARG 110  CZ  
466 1 Y 1 D ARG 91   ? NH1 ? C ARG 110  NH1 
467 1 Y 1 D ARG 91   ? NH2 ? C ARG 110  NH2 
468 1 Y 1 D PHE 93   ? CG  ? C PHE 112  CG  
469 1 Y 1 D PHE 93   ? CD1 ? C PHE 112  CD1 
470 1 Y 1 D PHE 93   ? CD2 ? C PHE 112  CD2 
471 1 Y 1 D PHE 93   ? CE1 ? C PHE 112  CE1 
472 1 Y 1 D PHE 93   ? CE2 ? C PHE 112  CE2 
473 1 Y 1 D PHE 93   ? CZ  ? C PHE 112  CZ  
474 1 Y 1 D LYS 95   ? CG  ? C LYS 114  CG  
475 1 Y 1 D LYS 95   ? CD  ? C LYS 114  CD  
476 1 Y 1 D LYS 95   ? CE  ? C LYS 114  CE  
477 1 Y 1 D LYS 95   ? NZ  ? C LYS 114  NZ  
478 1 Y 1 D ASP 96   ? CG  ? C ASP 115  CG  
479 1 Y 1 D ASP 96   ? OD1 ? C ASP 115  OD1 
480 1 Y 1 D ASP 96   ? OD2 ? C ASP 115  OD2 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8Z5R 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8Z5R 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8Z5R 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               ? 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8Z5R 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            . 
_refine.ls_d_res_low                             ? 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.002 ? 11501 ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.501 ? 15649 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 3.689 ? 1605  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.038 ? 1798  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.004 ? 1999  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     8Z5R 
_struct.title                        
'human phosphorylase kinase alpha/gamma/delta subcomplex - phosphorylation and Ca2+ bound state' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8Z5R 
_struct_keywords.text            'Kinase, glycogenolysis, CYTOSOLIC PROTEIN' 
_struct_keywords.pdbx_keywords   'CYTOSOLIC PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP KPB1_HUMAN  P46020 ? 1 
;MRSRSNSGVRLDGYARLVQQTILCHQNPVTGLLPASYDQKDAWVRDNVYSILAVWGLGLAYRKNADRDEDKAKAYELEQS
VVKLMRGLLHCMIRQVDKVESFKYSQSTKDSLHAKYNTKTCATVVGDDQWGHLQLDATSVYLLFLAQMTASGLHIIHSLD
EVNFIQNLVFYIEAAYKTADFGIWERGDKTNQGISELNASSVGMAKAALEALDELDLFGVKGGPQSVIHVLADEVQHCQS
ILNSLLPRASTSKEVDASLLSVVSFPAFAVEDSQLVELTKQEIITKLQGRYGCCRFLRDGYKTPKEDPNRLYYEPAELKL
FENIECEWPLFWTYFILDGVFSGNAEQVQEYKEALEAVLIKGKNGVPLLPELYSVPPDRVDEEYQNPHTVDRVPMGKLPH
MWGQSLYILGSLMAEGFLAPGEIDPLNRRFSTVPKPDVVVQVSILAETEEIKTILKDKGIYVETIAEVYPIRVQPARILS
HIYSSLGCNNRMKLSGRPYRHMGVLGTSKLYDIRKTIFTFTPQFIDQQQFYLALDNKMIVEMLRTDLSYLCSRWRMTGQP
TITFPISHSMLDEDGTSLNSSILAALRKMQDGYFGGARVQTGKLSEFLTTSCCTHLSFMDPGPEGKLYSEDYDDNYDYLE
SGNWMNDYDSTSHARCGDEVARYLDHLLAHTAPHPKLAPTSQKGGLDRFQAAVQTTCDLMSLVTKAKELHVQNVHMYLPT
KLFQASRPSFNLLDSPHPRQENQVPSVRVEIHLPRDQSGEVDFKALVLQLKETSSLQEQADILYMLYTMKGPDWNTELYN
ERSATVRELLTELYGKVGEIRHWGLIRYISGILRKKVEALDEACTDLLSHQKHLTVGLPPEPREKTISAPLPYEALTQLI
DEASEGDMSISILTQEIMVYLAMYMRTQPGLFAEMFRLRIGLIIQVMATELAHSLRCSAEEATEGLMNLSPSAMKNLLHH
ILSGKEFGVERSVRPTDSNVSPAISIHEIGAVGATKTERTGIMQLKSEIKQVEFRRLSISAESQSPGTSMTPSSGSFPSA
YDQQSSKDSRQGQWQRRRRLDGALNRVPVGFYQKVWKVLQKCHGLSVEGFVLPSSTTREMTPGEIKFSVHVESVLNRVPQ
PEYRQLLVEAILVLTMLADIEIHSIGSIIAVEKIVHIANDLFLQEQKTLGADDTMLAKDPASGICTLLYDSAPSGRFGTM
TYLSKAAATYVQEFLPHSICAMQ
;
1 
2 UNP PHKG1_HUMAN Q16816 ? 2 
;MTRDEALPDSHSAQDFYENYEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEVDILRK
VSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRALLEVICTLHKLNIVHRDLKPENILLDD
NMNIKLTDFGFSCQLEPGERLREVCGTPSYLAPEIIECSMNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLR
MIMSGNYQFGSPEWDDYSDTVKDLVSRFLVVQPQNRYTAEEALAHPFFQQYLVEEVRHFSPRGKFKVIALTVLASVRIYY
QYRRVKPVTREIVIRDPYALRPLRRLIDAYAFRIYGHWVKKGQQQNRAALFENTPKAVLLSLAEEDY
;
1 
3 UNP CALM3_HUMAN P0DP25 ? 3 
;MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDT
DSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK
;
1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8Z5R A 1  ? 1223 ? P46020 1 ? 1223 ? 1 1223 
2 2 8Z5R C 1  ? 387  ? Q16816 1 ? 387  ? 1 387  
3 3 8Z5R D 20 ? 168  ? P0DP25 1 ? 149  ? 1 149  
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
3 8Z5R ASP D 1  ? UNP P0DP25 ? ? 'expression tag' -18 1  
3 8Z5R TYR D 2  ? UNP P0DP25 ? ? 'expression tag' -17 2  
3 8Z5R LYS D 3  ? UNP P0DP25 ? ? 'expression tag' -16 3  
3 8Z5R ASP D 4  ? UNP P0DP25 ? ? 'expression tag' -15 4  
3 8Z5R ASP D 5  ? UNP P0DP25 ? ? 'expression tag' -14 5  
3 8Z5R ASP D 6  ? UNP P0DP25 ? ? 'expression tag' -13 6  
3 8Z5R ASP D 7  ? UNP P0DP25 ? ? 'expression tag' -12 7  
3 8Z5R LYS D 8  ? UNP P0DP25 ? ? 'expression tag' -11 8  
3 8Z5R SER D 9  ? UNP P0DP25 ? ? 'expression tag' -10 9  
3 8Z5R GLY D 10 ? UNP P0DP25 ? ? 'expression tag' -9  10 
3 8Z5R PRO D 11 ? UNP P0DP25 ? ? 'expression tag' -8  11 
3 8Z5R ASP D 12 ? UNP P0DP25 ? ? 'expression tag' -7  12 
3 8Z5R GLU D 13 ? UNP P0DP25 ? ? 'expression tag' -6  13 
3 8Z5R VAL D 14 ? UNP P0DP25 ? ? 'expression tag' -5  14 
3 8Z5R ASP D 15 ? UNP P0DP25 ? ? 'expression tag' -4  15 
3 8Z5R ALA D 16 ? UNP P0DP25 ? ? 'expression tag' -3  16 
3 8Z5R SER D 17 ? UNP P0DP25 ? ? 'expression tag' -2  17 
3 8Z5R GLY D 18 ? UNP P0DP25 ? ? 'expression tag' -1  18 
3 8Z5R ARG D 19 ? UNP P0DP25 ? ? 'expression tag' 0   19 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   trimeric 
_pdbx_struct_assembly.oligomeric_count     3 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 5    ? ILE A 22   ? SER A 5    ILE A 22   1 ? 18 
HELX_P HELX_P2  AA2 LEU A 23   ? GLN A 26   ? LEU A 23   GLN A 26   5 ? 4  
HELX_P HELX_P3  AA3 VAL A 44   ? ASN A 64   ? VAL A 44   ASN A 64   1 ? 21 
HELX_P HELX_P4  AA4 ARG A 67   ? ARG A 94   ? ARG A 67   ARG A 94   1 ? 28 
HELX_P HELX_P5  AA5 GLN A 95   ? TYR A 104  ? GLN A 95   TYR A 104  1 ? 10 
HELX_P HELX_P6  AA6 GLN A 134  ? GLY A 152  ? GLN A 134  GLY A 152  1 ? 19 
HELX_P HELX_P7  AA7 SER A 158  ? GLU A 173  ? SER A 158  GLU A 173  1 ? 16 
HELX_P HELX_P8  AA8 ALA A 174  ? THR A 178  ? ALA A 174  THR A 178  5 ? 5  
HELX_P HELX_P9  AA9 ASN A 198  ? LEU A 212  ? ASN A 198  LEU A 212  1 ? 15 
HELX_P HELX_P10 AB1 PHE A 218  ? GLY A 222  ? PHE A 218  GLY A 222  5 ? 5  
HELX_P HELX_P11 AB2 GLY A 223  ? VAL A 227  ? GLY A 223  VAL A 227  5 ? 5  
HELX_P HELX_P12 AB3 LEU A 231  ? LEU A 246  ? LEU A 231  LEU A 246  1 ? 16 
HELX_P HELX_P13 AB4 ASP A 256  ? VAL A 262  ? ASP A 256  VAL A 262  5 ? 7  
HELX_P HELX_P14 AB5 ASP A 272  ? LEU A 287  ? ASP A 272  LEU A 287  1 ? 16 
HELX_P HELX_P15 AB6 PRO A 329  ? SER A 342  ? PRO A 329  SER A 342  1 ? 14 
HELX_P HELX_P16 AB7 ALA A 345  ? LEU A 359  ? ALA A 345  LEU A 359  1 ? 15 
HELX_P HELX_P17 AB8 LYS A 363  ? GLY A 365  ? LYS A 363  GLY A 365  5 ? 3  
HELX_P HELX_P18 AB9 VAL A 380  ? ASN A 386  ? VAL A 380  ASN A 386  1 ? 7  
HELX_P HELX_P19 AC1 HIS A 400  ? GLU A 415  ? HIS A 400  GLU A 415  1 ? 16 
HELX_P HELX_P20 AC2 ALA A 419  ? ASP A 424  ? ALA A 419  ASP A 424  1 ? 6  
HELX_P HELX_P21 AC3 ARG A 428  ? VAL A 433  ? ARG A 428  VAL A 433  5 ? 6  
HELX_P HELX_P22 AC4 THR A 448  ? LYS A 458  ? THR A 448  LYS A 458  1 ? 11 
HELX_P HELX_P23 AC5 PRO A 475  ? SER A 484  ? PRO A 475  SER A 484  1 ? 10 
HELX_P HELX_P24 AC6 GLY A 503  ? SER A 508  ? GLY A 503  SER A 508  1 ? 6  
HELX_P HELX_P25 AC7 PRO A 522  ? ASP A 526  ? PRO A 522  ASP A 526  5 ? 5  
HELX_P HELX_P26 AC8 PHE A 530  ? LEU A 534  ? PHE A 530  LEU A 534  5 ? 5  
HELX_P HELX_P27 AC9 ASP A 535  ? ARG A 553  ? ASP A 535  ARG A 553  1 ? 19 
HELX_P HELX_P28 AD1 SER A 567  ? LEU A 571  ? SER A 567  LEU A 571  5 ? 5  
HELX_P HELX_P29 AD2 ASN A 579  ? ASP A 591  ? ASN A 579  ASP A 591  1 ? 13 
HELX_P HELX_P30 AD3 LYS A 603  ? THR A 609  ? LYS A 603  THR A 609  1 ? 7  
HELX_P HELX_P31 AD4 SER A 617  ? ASP A 620  ? SER A 617  ASP A 620  5 ? 4  
HELX_P HELX_P32 AD5 PHE A 763  ? THR A 773  ? PHE A 763  THR A 773  1 ? 11 
HELX_P HELX_P33 AD6 SER A 775  ? LYS A 790  ? SER A 775  LYS A 790  1 ? 16 
HELX_P HELX_P34 AD7 THR A 805  ? ARG A 821  ? THR A 805  ARG A 821  1 ? 17 
HELX_P HELX_P35 AD8 LEU A 825  ? ARG A 834  ? LEU A 825  ARG A 834  1 ? 10 
HELX_P HELX_P36 AD9 ALA A 839  ? SER A 849  ? ALA A 839  SER A 849  1 ? 11 
HELX_P HELX_P37 AE1 PRO A 872  ? GLU A 885  ? PRO A 872  GLU A 885  1 ? 14 
HELX_P HELX_P38 AE2 MET A 888  ? GLN A 908  ? MET A 888  GLN A 908  1 ? 21 
HELX_P HELX_P39 AE3 ILE A 920  ? ARG A 936  ? ILE A 920  ARG A 936  1 ? 17 
HELX_P HELX_P40 AE4 SER A 938  ? LEU A 949  ? SER A 938  LEU A 949  1 ? 12 
HELX_P HELX_P41 AE5 SER A 950  ? GLY A 964  ? SER A 950  GLY A 964  1 ? 15 
HELX_P HELX_P42 AE6 TRP A 1054 ? LEU A 1064 ? TRP A 1054 LEU A 1064 1 ? 11 
HELX_P HELX_P43 AE7 GLY A 1070 ? CYS A 1082 ? GLY A 1070 CYS A 1082 1 ? 13 
HELX_P HELX_P44 AE8 SER A 1095 ? MET A 1100 ? SER A 1095 MET A 1100 1 ? 6  
HELX_P HELX_P45 AE9 GLU A 1104 ? ASN A 1116 ? GLU A 1104 ASN A 1116 1 ? 13 
HELX_P HELX_P46 AF1 GLN A 1120 ? GLU A 1141 ? GLN A 1120 GLU A 1141 1 ? 22 
HELX_P HELX_P47 AF2 VAL A 1151 ? GLY A 1170 ? VAL A 1151 GLY A 1170 1 ? 20 
HELX_P HELX_P48 AF3 CYS A 1185 ? SER A 1191 ? CYS A 1185 SER A 1191 1 ? 7  
HELX_P HELX_P49 AF4 GLY A 1198 ? PHE A 1214 ? GLY A 1198 PHE A 1214 1 ? 17 
HELX_P HELX_P50 AF5 ALA B 13   ? TYR B 20   ? ALA C 13   TYR C 20   1 ? 8  
HELX_P HELX_P51 AF6 SER B 60   ? VAL B 81   ? SER C 60   VAL C 81   1 ? 22 
HELX_P HELX_P52 AF7 GLU B 111  ? VAL B 120  ? GLU C 111  VAL C 120  1 ? 10 
HELX_P HELX_P53 AF8 SER B 123  ? LEU B 144  ? SER C 123  LEU C 144  1 ? 22 
HELX_P HELX_P54 AF9 LYS B 152  ? GLU B 154  ? LYS C 152  GLU C 154  5 ? 3  
HELX_P HELX_P55 AG1 ALA B 192  ? SER B 199  ? ALA C 192  SER C 199  1 ? 8  
HELX_P HELX_P56 AG2 GLU B 210  ? GLY B 226  ? GLU C 210  GLY C 226  1 ? 17 
HELX_P HELX_P57 AG3 LYS B 234  ? GLY B 245  ? LYS C 234  GLY C 245  1 ? 12 
HELX_P HELX_P58 AG4 GLY B 250  ? ASP B 255  ? GLY C 250  ASP C 255  1 ? 6  
HELX_P HELX_P59 AG5 SER B 258  ? LEU B 269  ? SER C 258  LEU C 269  1 ? 12 
HELX_P HELX_P60 AG6 THR B 278  ? ALA B 284  ? THR C 278  ALA C 284  1 ? 7  
HELX_P HELX_P61 AG7 SER B 300  ? TYR B 320  ? SER C 300  TYR C 320  1 ? 21 
HELX_P HELX_P62 AG8 GLN B 321  ? VAL B 325  ? GLN C 321  VAL C 325  5 ? 5  
HELX_P HELX_P63 AG9 THR B 329  ? ASP B 336  ? THR C 329  ASP C 336  1 ? 8  
HELX_P HELX_P64 AH1 LEU B 340  ? TYR B 355  ? LEU C 340  TYR C 355  1 ? 16 
HELX_P HELX_P65 AH2 ASN B 366  ? PHE B 371  ? ASN C 366  PHE C 371  5 ? 6  
HELX_P HELX_P66 AH3 ALA B 377  ? SER B 381  ? ALA C 377  SER C 381  5 ? 5  
HELX_P HELX_P67 AH4 THR C 25   ? ASP C 40   ? THR D 6    ASP D 21   1 ? 16 
HELX_P HELX_P68 AH5 THR C 48   ? GLY C 60   ? THR D 29   GLY D 41   1 ? 13 
HELX_P HELX_P69 AH6 THR C 64   ? ASP C 76   ? THR D 45   ASP D 57   1 ? 13 
HELX_P HELX_P70 AH7 ASP C 84   ? ALA C 93   ? ASP D 65   ALA D 74   1 ? 10 
HELX_P HELX_P71 AH8 ASP C 98   ? ASP C 113  ? ASP D 79   ASP D 94   1 ? 16 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
covale1  covale both ? A GLU 100  C ? ? ? 1_555 A SEP 101  N ? ? A GLU 100  A SEP 101  1_555 ? ? ? ? ? ? ? 1.269 ? ? 
covale2  covale both ? A SEP 101  C ? ? ? 1_555 A PHE 102  N ? ? A SEP 101  A PHE 102  1_555 ? ? ? ? ? ? ? 1.302 ? ? 
covale3  covale both ? A TYR 104  C ? ? ? 1_555 A SEP 105  N ? ? A TYR 104  A SEP 105  1_555 ? ? ? ? ? ? ? 1.332 ? ? 
covale4  covale both ? A SEP 105  C ? ? ? 1_555 A GLN 106  N ? ? A SEP 105  A GLN 106  1_555 ? ? ? ? ? ? ? 1.329 ? ? 
covale5  covale both ? A GLN 106  C ? ? ? 1_555 A SEP 107  N ? ? A GLN 106  A SEP 107  1_555 ? ? ? ? ? ? ? 1.330 ? ? 
covale6  covale both ? A SEP 107  C ? ? ? 1_555 A THR 108  N ? ? A SEP 107  A THR 108  1_555 ? ? ? ? ? ? ? 1.330 ? ? 
covale7  covale both ? A ASP 110  C ? ? ? 1_555 A SEP 111  N ? ? A ASP 110  A SEP 111  1_555 ? ? ? ? ? ? ? 1.329 ? ? 
covale8  covale both ? A SEP 111  C ? ? ? 1_555 A LEU 112  N ? ? A SEP 111  A LEU 112  1_555 ? ? ? ? ? ? ? 1.329 ? ? 
covale9  covale both ? A SER 200  C ? ? ? 1_555 A SEP 201  N ? ? A SER 200  A SEP 201  1_555 ? ? ? ? ? ? ? 1.329 ? ? 
covale10 covale both ? A SEP 201  C ? ? ? 1_555 A VAL 202  N ? ? A SEP 201  A VAL 202  1_555 ? ? ? ? ? ? ? 1.331 ? ? 
covale11 covale both ? A GLN 239  C ? ? ? 1_555 A SEP 240  N ? ? A GLN 239  A SEP 240  1_555 ? ? ? ? ? ? ? 1.329 ? ? 
covale12 covale both ? A SEP 240  C ? ? ? 1_555 A ILE 241  N ? ? A SEP 240  A ILE 241  1_555 ? ? ? ? ? ? ? 1.330 ? ? 
covale13 covale both ? A TYR 373  C ? ? ? 1_555 A SEP 374  N ? ? A TYR 373  A SEP 374  1_555 ? ? ? ? ? ? ? 1.329 ? ? 
covale14 covale both ? A SEP 374  C ? ? ? 1_555 A VAL 375  N ? ? A SEP 374  A VAL 375  1_555 ? ? ? ? ? ? ? 1.329 ? ? 
covale15 covale both ? A LEU 479  C ? ? ? 1_555 A SEP 480  N ? ? A LEU 479  A SEP 480  1_555 ? ? ? ? ? ? ? 1.329 ? ? 
covale16 covale both ? A SEP 480  C ? ? ? 1_555 A HIS 481  N ? ? A SEP 480  A HIS 481  1_555 ? ? ? ? ? ? ? 1.329 ? ? 
covale17 covale both ? A LEU 547  C ? ? ? 1_555 A SEP 548  N ? ? A LEU 547  A SEP 548  1_555 ? ? ? ? ? ? ? 1.330 ? ? 
covale18 covale both ? A SEP 548  C ? ? ? 1_555 A TYR 549  N ? ? A SEP 548  A TYR 549  1_555 ? ? ? ? ? ? ? 1.331 ? ? 
covale19 covale both ? A LEU 854  C ? ? ? 1_555 A TPO 855  N ? ? A LEU 854  A TPO 855  1_555 ? ? ? ? ? ? ? 1.329 ? ? 
covale20 covale both ? A TPO 855  C ? ? ? 1_555 A VAL 856  N ? ? A TPO 855  A VAL 856  1_555 ? ? ? ? ? ? ? 1.329 ? ? 
covale21 covale both ? A LEU 962  C ? ? ? 1_555 A SEP 963  N ? ? A LEU 962  A SEP 963  1_555 ? ? ? ? ? ? ? 1.329 ? ? 
covale22 covale both ? A SEP 963  C ? ? ? 1_555 A GLY 964  N ? ? A SEP 963  A GLY 964  1_555 ? ? ? ? ? ? ? 1.329 ? ? 
covale23 covale both ? A ASP 1173 C ? ? ? 1_555 A TPO 1174 N ? ? A ASP 1173 A TPO 1174 1_555 ? ? ? ? ? ? ? 1.330 ? ? 
covale24 covale both ? A TPO 1174 C ? ? ? 1_555 A MET 1175 N ? ? A TPO 1174 A MET 1175 1_555 ? ? ? ? ? ? ? 1.329 ? ? 
covale25 covale both ? A PRO 1193 C ? ? ? 1_555 A SEP 1194 N ? ? A PRO 1193 A SEP 1194 1_555 ? ? ? ? ? ? ? 1.329 ? ? 
covale26 covale both ? A SEP 1194 C ? ? ? 1_555 A GLY 1195 N ? ? A SEP 1194 A GLY 1195 1_555 ? ? ? ? ? ? ? 1.329 ? ? 
covale27 covale both ? A HIS 1217 C ? ? ? 1_555 A SEP 1218 N ? ? A HIS 1217 A SEP 1218 1_555 ? ? ? ? ? ? ? 1.329 ? ? 
covale28 covale both ? A SEP 1218 C ? ? ? 1_555 A ILE 1219 N ? ? A SEP 1218 A ILE 1219 1_555 ? ? ? ? ? ? ? 1.329 ? ? 
# 
_struct_conn_type.id          covale 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1  SEP A 101  ? . . . . SEP A 101  ? 1_555 . . . . . . . SER 1 SEP Phosphorylation 'Named protein modification' 
2  SEP A 105  ? . . . . SEP A 105  ? 1_555 . . . . . . . SER 1 SEP Phosphorylation 'Named protein modification' 
3  SEP A 107  ? . . . . SEP A 107  ? 1_555 . . . . . . . SER 1 SEP Phosphorylation 'Named protein modification' 
4  SEP A 111  ? . . . . SEP A 111  ? 1_555 . . . . . . . SER 1 SEP Phosphorylation 'Named protein modification' 
5  SEP A 201  ? . . . . SEP A 201  ? 1_555 . . . . . . . SER 1 SEP Phosphorylation 'Named protein modification' 
6  SEP A 240  ? . . . . SEP A 240  ? 1_555 . . . . . . . SER 1 SEP Phosphorylation 'Named protein modification' 
7  SEP A 374  ? . . . . SEP A 374  ? 1_555 . . . . . . . SER 1 SEP Phosphorylation 'Named protein modification' 
8  SEP A 480  ? . . . . SEP A 480  ? 1_555 . . . . . . . SER 1 SEP Phosphorylation 'Named protein modification' 
9  SEP A 548  ? . . . . SEP A 548  ? 1_555 . . . . . . . SER 1 SEP Phosphorylation 'Named protein modification' 
10 TPO A 855  ? . . . . TPO A 855  ? 1_555 . . . . . . . THR 1 TPO Phosphorylation 'Named protein modification' 
11 SEP A 963  ? . . . . SEP A 963  ? 1_555 . . . . . . . SER 1 SEP Phosphorylation 'Named protein modification' 
12 TPO A 1174 ? . . . . TPO A 1174 ? 1_555 . . . . . . . THR 1 TPO Phosphorylation 'Named protein modification' 
13 SEP A 1194 ? . . . . SEP A 1194 ? 1_555 . . . . . . . SER 1 SEP Phosphorylation 'Named protein modification' 
14 SEP A 1218 ? . . . . SEP A 1218 ? 1_555 . . . . . . . SER 1 SEP Phosphorylation 'Named protein modification' 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 2 ? 
AA2 ? 3 ? 
AA3 ? 2 ? 
AA4 ? 2 ? 
AA5 ? 3 ? 
AA6 ? 3 ? 
AA7 ? 4 ? 
AA8 ? 2 ? 
AA9 ? 2 ? 
AB1 ? 3 ? 
AB2 ? 5 ? 
AB3 ? 2 ? 
AB4 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA5 1 2 ? parallel      
AA5 2 3 ? parallel      
AA6 1 2 ? parallel      
AA6 2 3 ? parallel      
AA7 1 2 ? parallel      
AA7 2 3 ? anti-parallel 
AA7 3 4 ? parallel      
AA8 1 2 ? anti-parallel 
AA9 1 2 ? parallel      
AB1 1 2 ? anti-parallel 
AB1 2 3 ? parallel      
AB2 1 2 ? anti-parallel 
AB2 2 3 ? anti-parallel 
AB2 3 4 ? anti-parallel 
AB2 4 5 ? anti-parallel 
AB3 1 2 ? anti-parallel 
AB4 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ASP A 41   ? TRP A 43   ? ASP A 41   TRP A 43   
AA1 2 LYS A 115  ? ASN A 117  ? LYS A 115  ASN A 117  
AA2 1 GLN A 288  ? GLY A 289  ? GLN A 288  GLY A 289  
AA2 2 GLY A 292  ? CYS A 294  ? GLY A 292  CYS A 294  
AA2 3 GLU A 327  ? TRP A 328  ? GLU A 327  TRP A 328  
AA3 1 ILE A 360  ? LYS A 361  ? ILE A 360  LYS A 361  
AA3 2 PRO A 367  ? LEU A 368  ? PRO A 367  LEU A 368  
AA4 1 LEU A 372  ? SEP A 374  ? LEU A 372  SEP A 374  
AA4 2 VAL A 393  ? MET A 395  ? VAL A 393  MET A 395  
AA5 1 GLU A 463  ? THR A 464  ? GLU A 463  THR A 464  
AA5 2 VAL A 440  ? ALA A 446  ? VAL A 440  ALA A 446  
AA5 3 THR A 561  ? ILE A 566  ? THR A 561  ILE A 566  
AA6 1 GLU A 463  ? THR A 464  ? GLU A 463  THR A 464  
AA6 2 VAL A 440  ? ALA A 446  ? VAL A 440  ALA A 446  
AA6 3 VAL A 599  ? THR A 601  ? VAL A 599  THR A 601  
AA7 1 ILE A 471  ? GLN A 474  ? ILE A 471  GLN A 474  
AA7 2 THR A 516  ? PHE A 520  ? THR A 516  PHE A 520  
AA7 3 LEU A 510  ? ILE A 513  ? LEU A 510  ILE A 513  
AA7 4 CYS A 613  ? HIS A 615  ? CYS A 613  HIS A 615  
AA8 1 CYS A 488  ? ASN A 489  ? CYS A 488  ASN A 489  
AA8 2 LEU A 494  ? SER A 495  ? LEU A 494  SER A 495  
AA9 1 HIS A 853  ? TPO A 855  ? HIS A 853  TPO A 855  
AA9 2 ARG A 917  ? ARG A 919  ? ARG A 917  ARG A 919  
AB1 1 LEU A 1092 ? PRO A 1093 ? LEU A 1092 PRO A 1093 
AB1 2 GLY A 1084 ? SER A 1086 ? GLY A 1084 SER A 1086 
AB1 3 ILE A 1148 ? ALA A 1150 ? ILE A 1148 ALA A 1150 
AB2 1 ILE B 25   ? ARG B 28   ? ILE C 25   ARG C 28   
AB2 2 SER B 32   ? ARG B 36   ? SER C 32   ARG C 36   
AB2 3 ALA B 47   ? ASP B 52   ? ALA C 47   ASP C 52   
AB2 4 PHE B 99   ? PHE B 104  ? PHE C 99   PHE C 104  
AB2 5 ASP B 92   ? GLU B 95   ? ASP C 92   GLU C 95   
AB3 1 ILE B 146  ? VAL B 147  ? ILE C 146  VAL C 147  
AB3 2 CYS B 173  ? GLN B 174  ? CYS C 173  GLN C 174  
AB4 1 ILE B 156  ? LEU B 158  ? ILE C 156  LEU C 158  
AB4 2 ILE B 164  ? LEU B 166  ? ILE C 164  LEU C 166  
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N ALA A 42   ? N ALA A 42   O TYR A 116  ? O TYR A 116  
AA2 1 2 N GLY A 289  ? N GLY A 289  O GLY A 292  ? O GLY A 292  
AA2 2 3 N CYS A 293  ? N CYS A 293  O TRP A 328  ? O TRP A 328  
AA3 1 2 N ILE A 360  ? N ILE A 360  O LEU A 368  ? O LEU A 368  
AA4 1 2 N SEP A 374  ? N SEP A 374  O VAL A 393  ? O VAL A 393  
AA5 1 2 O GLU A 463  ? O GLU A 463  N ALA A 446  ? N ALA A 446  
AA5 2 3 N SER A 443  ? N SER A 443  O ILE A 562  ? O ILE A 562  
AA6 1 2 O GLU A 463  ? O GLU A 463  N ALA A 446  ? N ALA A 446  
AA6 2 3 N VAL A 442  ? N VAL A 442  O GLN A 600  ? O GLN A 600  
AA7 1 2 N ARG A 472  ? N ARG A 472  O THR A 519  ? O THR A 519  
AA7 2 3 O PHE A 518  ? O PHE A 518  N TYR A 511  ? N TYR A 511  
AA7 3 4 N ASP A 512  ? N ASP A 512  O THR A 614  ? O THR A 614  
AA8 1 2 N ASN A 489  ? N ASN A 489  O LEU A 494  ? O LEU A 494  
AA9 1 2 N HIS A 853  ? N HIS A 853  O LEU A 918  ? O LEU A 918  
AB1 1 2 O LEU A 1092 ? O LEU A 1092 N LEU A 1085 ? N LEU A 1085 
AB1 2 3 N SER A 1086 ? N SER A 1086 O ILE A 1149 ? O ILE A 1149 
AB2 1 2 N LEU B 26   ? N LEU C 26   O VAL B 34   ? O VAL C 34   
AB2 2 3 N ARG B 35   ? N ARG C 35   O VAL B 48   ? O VAL C 48   
AB2 3 4 N ALA B 47   ? N ALA C 47   O PHE B 104  ? O PHE C 104  
AB2 4 5 O PHE B 101  ? O PHE C 101  N TYR B 94   ? N TYR C 94   
AB3 1 2 N VAL B 147  ? N VAL C 147  O CYS B 173  ? O CYS C 173  
AB4 1 2 N LEU B 157  ? N LEU C 157  O LYS B 165  ? O LYS C 165  
# 
_pdbx_entry_details.entry_id                   8Z5R 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_ligand_of_interest     ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 HIS A 25   ? ? -108.25 40.62   
2  1 ASN A 27   ? ? 57.97   74.28   
3  1 VAL A 29   ? ? 74.68   -54.06  
4  1 SER A 36   ? ? 62.23   170.82  
5  1 TYR A 37   ? ? 56.05   -163.96 
6  1 ASP A 38   ? ? -95.79  57.67   
7  1 SEP A 105  ? ? 56.66   81.50   
8  1 THR A 118  ? ? -78.99  -161.58 
9  1 LYS A 119  ? ? -44.47  151.21  
10 1 THR A 120  ? ? 79.54   -4.17   
11 1 HIS A 132  ? ? -95.73  57.66   
12 1 ILE A 155  ? ? -125.62 -53.95  
13 1 GLN A 192  ? ? 47.72   23.16   
14 1 LEU A 212  ? ? -95.77  31.25   
15 1 GLU A 214  ? ? -140.09 29.74   
16 1 LEU A 246  ? ? -117.71 54.07   
17 1 ALA A 267  ? ? 74.65   -12.80  
18 1 LYS A 305  ? ? -146.03 -158.62 
19 1 GLU A 306  ? ? 55.67   18.87   
20 1 ASP A 307  ? ? 55.64   76.91   
21 1 SER A 342  ? ? -67.40  -72.87  
22 1 ALA A 466  ? ? -76.92  -169.77 
23 1 GLU A 467  ? ? 53.19   16.76   
24 1 TRP A 554  ? ? 37.80   59.15   
25 1 LYS A 790  ? ? -142.99 18.79   
26 1 TRP A 823  ? ? -92.19  54.54   
27 1 GLU A 885  ? ? 62.20   -139.13 
28 1 MET A 888  ? ? 64.21   -66.80  
29 1 PRO A 909  ? ? -84.34  41.53   
30 1 GLU A 914  ? ? 69.12   -4.23   
31 1 PHE A 1090 ? ? 56.90   -162.50 
32 1 VAL C 120  ? ? 61.35   -68.96  
33 1 ARG C 149  ? ? 55.77   14.53   
34 1 MET C 200  ? ? -62.76  -71.28  
35 1 ASN C 201  ? ? -125.39 -67.08  
36 1 ASP C 256  ? ? -93.44  52.81   
37 1 ALA C 377  ? ? -127.21 -168.55 
38 1 THR D 29   ? ? 72.84   137.32  
39 1 LYS D 78   ? ? 70.02   -129.37 
# 
_pdbx_validate_peptide_omega.id               1 
_pdbx_validate_peptide_omega.PDB_model_num    1 
_pdbx_validate_peptide_omega.auth_comp_id_1   PRO 
_pdbx_validate_peptide_omega.auth_asym_id_1   A 
_pdbx_validate_peptide_omega.auth_seq_id_1    859 
_pdbx_validate_peptide_omega.PDB_ins_code_1   ? 
_pdbx_validate_peptide_omega.label_alt_id_1   ? 
_pdbx_validate_peptide_omega.auth_comp_id_2   PRO 
_pdbx_validate_peptide_omega.auth_asym_id_2   A 
_pdbx_validate_peptide_omega.auth_seq_id_2    860 
_pdbx_validate_peptide_omega.PDB_ins_code_2   ? 
_pdbx_validate_peptide_omega.label_alt_id_2   ? 
_pdbx_validate_peptide_omega.omega            149.79 
# 
loop_
_pdbx_struct_mod_residue.id 
_pdbx_struct_mod_residue.label_asym_id 
_pdbx_struct_mod_residue.label_comp_id 
_pdbx_struct_mod_residue.label_seq_id 
_pdbx_struct_mod_residue.auth_asym_id 
_pdbx_struct_mod_residue.auth_comp_id 
_pdbx_struct_mod_residue.auth_seq_id 
_pdbx_struct_mod_residue.PDB_ins_code 
_pdbx_struct_mod_residue.parent_comp_id 
_pdbx_struct_mod_residue.details 
1  A SEP 101  A SEP 101  ? SER 'modified residue' 
2  A SEP 105  A SEP 105  ? SER 'modified residue' 
3  A SEP 107  A SEP 107  ? SER 'modified residue' 
4  A SEP 111  A SEP 111  ? SER 'modified residue' 
5  A SEP 201  A SEP 201  ? SER 'modified residue' 
6  A SEP 240  A SEP 240  ? SER 'modified residue' 
7  A SEP 374  A SEP 374  ? SER 'modified residue' 
8  A SEP 480  A SEP 480  ? SER 'modified residue' 
9  A SEP 548  A SEP 548  ? SER 'modified residue' 
10 A TPO 855  A TPO 855  ? THR 'modified residue' 
11 A SEP 963  A SEP 963  ? SER 'modified residue' 
12 A TPO 1174 A TPO 1174 ? THR 'modified residue' 
13 A SEP 1194 A SEP 1194 ? SER 'modified residue' 
14 A SEP 1218 A SEP 1218 ? SER 'modified residue' 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8Z5R 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    8Z5R 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.52 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               101907 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            6.8 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 
'human phosphorylase kinase alpha/gamma/delta subcomplex - phosphorylation and Ca2+ bound state' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       '1, 2, 3' 
# 
_em_imaging.entry_id                        8Z5R 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               OTHER 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             1000 
_em_imaging.nominal_defocus_max             2000 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              8Z5R 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                8Z5R 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A MET 1    ? A MET 1    
2   1 Y 1 A ARG 2    ? A ARG 2    
3   1 Y 1 A SER 3    ? A SER 3    
4   1 Y 1 A ARG 4    ? A ARG 4    
5   1 Y 1 A GLY 622  ? A GLY 622  
6   1 Y 1 A PRO 623  ? A PRO 623  
7   1 Y 1 A GLU 624  ? A GLU 624  
8   1 Y 1 A GLY 625  ? A GLY 625  
9   1 Y 1 A LYS 626  ? A LYS 626  
10  1 Y 1 A LEU 627  ? A LEU 627  
11  1 Y 1 A TYR 628  ? A TYR 628  
12  1 Y 1 A SEP 629  ? A SEP 629  
13  1 Y 1 A GLU 630  ? A GLU 630  
14  1 Y 1 A ASP 631  ? A ASP 631  
15  1 Y 1 A TYR 632  ? A TYR 632  
16  1 Y 1 A ASP 633  ? A ASP 633  
17  1 Y 1 A ASP 634  ? A ASP 634  
18  1 Y 1 A ASN 635  ? A ASN 635  
19  1 Y 1 A TYR 636  ? A TYR 636  
20  1 Y 1 A ASP 637  ? A ASP 637  
21  1 Y 1 A TYR 638  ? A TYR 638  
22  1 Y 1 A LEU 639  ? A LEU 639  
23  1 Y 1 A GLU 640  ? A GLU 640  
24  1 Y 1 A SER 641  ? A SER 641  
25  1 Y 1 A GLY 642  ? A GLY 642  
26  1 Y 1 A ASN 643  ? A ASN 643  
27  1 Y 1 A TRP 644  ? A TRP 644  
28  1 Y 1 A MET 645  ? A MET 645  
29  1 Y 1 A ASN 646  ? A ASN 646  
30  1 Y 1 A ASP 647  ? A ASP 647  
31  1 Y 1 A TYR 648  ? A TYR 648  
32  1 Y 1 A ASP 649  ? A ASP 649  
33  1 Y 1 A SER 650  ? A SER 650  
34  1 Y 1 A THR 651  ? A THR 651  
35  1 Y 1 A SER 652  ? A SER 652  
36  1 Y 1 A HIS 653  ? A HIS 653  
37  1 Y 1 A ALA 654  ? A ALA 654  
38  1 Y 1 A ARG 655  ? A ARG 655  
39  1 Y 1 A CYS 656  ? A CYS 656  
40  1 Y 1 A GLY 657  ? A GLY 657  
41  1 Y 1 A ASP 658  ? A ASP 658  
42  1 Y 1 A GLU 659  ? A GLU 659  
43  1 Y 1 A VAL 660  ? A VAL 660  
44  1 Y 1 A ALA 661  ? A ALA 661  
45  1 Y 1 A ARG 662  ? A ARG 662  
46  1 Y 1 A TYR 663  ? A TYR 663  
47  1 Y 1 A LEU 664  ? A LEU 664  
48  1 Y 1 A ASP 665  ? A ASP 665  
49  1 Y 1 A HIS 666  ? A HIS 666  
50  1 Y 1 A LEU 667  ? A LEU 667  
51  1 Y 1 A LEU 668  ? A LEU 668  
52  1 Y 1 A ALA 669  ? A ALA 669  
53  1 Y 1 A HIS 670  ? A HIS 670  
54  1 Y 1 A TPO 671  ? A TPO 671  
55  1 Y 1 A ALA 672  ? A ALA 672  
56  1 Y 1 A PRO 673  ? A PRO 673  
57  1 Y 1 A HIS 674  ? A HIS 674  
58  1 Y 1 A PRO 675  ? A PRO 675  
59  1 Y 1 A LYS 676  ? A LYS 676  
60  1 Y 1 A LEU 677  ? A LEU 677  
61  1 Y 1 A ALA 678  ? A ALA 678  
62  1 Y 1 A PRO 679  ? A PRO 679  
63  1 Y 1 A THR 680  ? A THR 680  
64  1 Y 1 A SER 681  ? A SER 681  
65  1 Y 1 A GLN 682  ? A GLN 682  
66  1 Y 1 A LYS 683  ? A LYS 683  
67  1 Y 1 A GLY 684  ? A GLY 684  
68  1 Y 1 A GLY 685  ? A GLY 685  
69  1 Y 1 A LEU 686  ? A LEU 686  
70  1 Y 1 A ASP 687  ? A ASP 687  
71  1 Y 1 A ARG 688  ? A ARG 688  
72  1 Y 1 A PHE 689  ? A PHE 689  
73  1 Y 1 A GLN 690  ? A GLN 690  
74  1 Y 1 A ALA 691  ? A ALA 691  
75  1 Y 1 A ALA 692  ? A ALA 692  
76  1 Y 1 A VAL 693  ? A VAL 693  
77  1 Y 1 A GLN 694  ? A GLN 694  
78  1 Y 1 A THR 695  ? A THR 695  
79  1 Y 1 A THR 696  ? A THR 696  
80  1 Y 1 A CYS 697  ? A CYS 697  
81  1 Y 1 A ASP 698  ? A ASP 698  
82  1 Y 1 A LEU 699  ? A LEU 699  
83  1 Y 1 A MET 700  ? A MET 700  
84  1 Y 1 A SEP 701  ? A SEP 701  
85  1 Y 1 A LEU 702  ? A LEU 702  
86  1 Y 1 A VAL 703  ? A VAL 703  
87  1 Y 1 A THR 704  ? A THR 704  
88  1 Y 1 A LYS 705  ? A LYS 705  
89  1 Y 1 A ALA 706  ? A ALA 706  
90  1 Y 1 A LYS 707  ? A LYS 707  
91  1 Y 1 A GLU 708  ? A GLU 708  
92  1 Y 1 A LEU 709  ? A LEU 709  
93  1 Y 1 A HIS 710  ? A HIS 710  
94  1 Y 1 A VAL 711  ? A VAL 711  
95  1 Y 1 A GLN 712  ? A GLN 712  
96  1 Y 1 A ASN 713  ? A ASN 713  
97  1 Y 1 A VAL 714  ? A VAL 714  
98  1 Y 1 A HIS 715  ? A HIS 715  
99  1 Y 1 A MET 716  ? A MET 716  
100 1 Y 1 A TYR 717  ? A TYR 717  
101 1 Y 1 A LEU 718  ? A LEU 718  
102 1 Y 1 A PRO 719  ? A PRO 719  
103 1 Y 1 A THR 720  ? A THR 720  
104 1 Y 1 A LYS 721  ? A LYS 721  
105 1 Y 1 A LEU 722  ? A LEU 722  
106 1 Y 1 A PHE 723  ? A PHE 723  
107 1 Y 1 A GLN 724  ? A GLN 724  
108 1 Y 1 A ALA 725  ? A ALA 725  
109 1 Y 1 A SEP 726  ? A SEP 726  
110 1 Y 1 A ARG 727  ? A ARG 727  
111 1 Y 1 A PRO 728  ? A PRO 728  
112 1 Y 1 A SEP 729  ? A SEP 729  
113 1 Y 1 A PHE 730  ? A PHE 730  
114 1 Y 1 A ASN 731  ? A ASN 731  
115 1 Y 1 A LEU 732  ? A LEU 732  
116 1 Y 1 A LEU 733  ? A LEU 733  
117 1 Y 1 A ASP 734  ? A ASP 734  
118 1 Y 1 A SEP 735  ? A SEP 735  
119 1 Y 1 A PRO 736  ? A PRO 736  
120 1 Y 1 A HIS 737  ? A HIS 737  
121 1 Y 1 A PRO 738  ? A PRO 738  
122 1 Y 1 A ARG 739  ? A ARG 739  
123 1 Y 1 A GLN 740  ? A GLN 740  
124 1 Y 1 A GLU 741  ? A GLU 741  
125 1 Y 1 A ASN 742  ? A ASN 742  
126 1 Y 1 A GLN 743  ? A GLN 743  
127 1 Y 1 A VAL 744  ? A VAL 744  
128 1 Y 1 A PRO 745  ? A PRO 745  
129 1 Y 1 A SEP 746  ? A SEP 746  
130 1 Y 1 A VAL 747  ? A VAL 747  
131 1 Y 1 A ARG 748  ? A ARG 748  
132 1 Y 1 A VAL 749  ? A VAL 749  
133 1 Y 1 A GLU 750  ? A GLU 750  
134 1 Y 1 A ILE 751  ? A ILE 751  
135 1 Y 1 A HIS 752  ? A HIS 752  
136 1 Y 1 A LEU 753  ? A LEU 753  
137 1 Y 1 A PRO 754  ? A PRO 754  
138 1 Y 1 A ARG 755  ? A ARG 755  
139 1 Y 1 A ASP 756  ? A ASP 756  
140 1 Y 1 A GLN 757  ? A GLN 757  
141 1 Y 1 A SEP 758  ? A SEP 758  
142 1 Y 1 A GLY 759  ? A GLY 759  
143 1 Y 1 A GLU 760  ? A GLU 760  
144 1 Y 1 A VAL 761  ? A VAL 761  
145 1 Y 1 A PHE 967  ? A PHE 967  
146 1 Y 1 A GLY 968  ? A GLY 968  
147 1 Y 1 A VAL 969  ? A VAL 969  
148 1 Y 1 A GLU 970  ? A GLU 970  
149 1 Y 1 A ARG 971  ? A ARG 971  
150 1 Y 1 A SEP 972  ? A SEP 972  
151 1 Y 1 A VAL 973  ? A VAL 973  
152 1 Y 1 A ARG 974  ? A ARG 974  
153 1 Y 1 A PRO 975  ? A PRO 975  
154 1 Y 1 A THR 976  ? A THR 976  
155 1 Y 1 A ASP 977  ? A ASP 977  
156 1 Y 1 A SER 978  ? A SER 978  
157 1 Y 1 A ASN 979  ? A ASN 979  
158 1 Y 1 A VAL 980  ? A VAL 980  
159 1 Y 1 A SEP 981  ? A SEP 981  
160 1 Y 1 A PRO 982  ? A PRO 982  
161 1 Y 1 A ALA 983  ? A ALA 983  
162 1 Y 1 A ILE 984  ? A ILE 984  
163 1 Y 1 A SEP 985  ? A SEP 985  
164 1 Y 1 A ILE 986  ? A ILE 986  
165 1 Y 1 A HIS 987  ? A HIS 987  
166 1 Y 1 A GLU 988  ? A GLU 988  
167 1 Y 1 A ILE 989  ? A ILE 989  
168 1 Y 1 A GLY 990  ? A GLY 990  
169 1 Y 1 A ALA 991  ? A ALA 991  
170 1 Y 1 A VAL 992  ? A VAL 992  
171 1 Y 1 A GLY 993  ? A GLY 993  
172 1 Y 1 A ALA 994  ? A ALA 994  
173 1 Y 1 A TPO 995  ? A TPO 995  
174 1 Y 1 A LYS 996  ? A LYS 996  
175 1 Y 1 A THR 997  ? A THR 997  
176 1 Y 1 A GLU 998  ? A GLU 998  
177 1 Y 1 A ARG 999  ? A ARG 999  
178 1 Y 1 A TPO 1000 ? A TPO 1000 
179 1 Y 1 A GLY 1001 ? A GLY 1001 
180 1 Y 1 A ILE 1002 ? A ILE 1002 
181 1 Y 1 A MET 1003 ? A MET 1003 
182 1 Y 1 A GLN 1004 ? A GLN 1004 
183 1 Y 1 A LEU 1005 ? A LEU 1005 
184 1 Y 1 A LYS 1006 ? A LYS 1006 
185 1 Y 1 A SEP 1007 ? A SEP 1007 
186 1 Y 1 A GLU 1008 ? A GLU 1008 
187 1 Y 1 A ILE 1009 ? A ILE 1009 
188 1 Y 1 A LYS 1010 ? A LYS 1010 
189 1 Y 1 A GLN 1011 ? A GLN 1011 
190 1 Y 1 A VAL 1012 ? A VAL 1012 
191 1 Y 1 A GLU 1013 ? A GLU 1013 
192 1 Y 1 A PHE 1014 ? A PHE 1014 
193 1 Y 1 A ARG 1015 ? A ARG 1015 
194 1 Y 1 A ARG 1016 ? A ARG 1016 
195 1 Y 1 A LEU 1017 ? A LEU 1017 
196 1 Y 1 A SEP 1018 ? A SEP 1018 
197 1 Y 1 A ILE 1019 ? A ILE 1019 
198 1 Y 1 A SEP 1020 ? A SEP 1020 
199 1 Y 1 A ALA 1021 ? A ALA 1021 
200 1 Y 1 A GLU 1022 ? A GLU 1022 
201 1 Y 1 A SEP 1023 ? A SEP 1023 
202 1 Y 1 A GLN 1024 ? A GLN 1024 
203 1 Y 1 A SEP 1025 ? A SEP 1025 
204 1 Y 1 A PRO 1026 ? A PRO 1026 
205 1 Y 1 A GLY 1027 ? A GLY 1027 
206 1 Y 1 A THR 1028 ? A THR 1028 
207 1 Y 1 A SER 1029 ? A SER 1029 
208 1 Y 1 A MET 1030 ? A MET 1030 
209 1 Y 1 A TPO 1031 ? A TPO 1031 
210 1 Y 1 A PRO 1032 ? A PRO 1032 
211 1 Y 1 A SER 1033 ? A SER 1033 
212 1 Y 1 A SER 1034 ? A SER 1034 
213 1 Y 1 A GLY 1035 ? A GLY 1035 
214 1 Y 1 A SER 1036 ? A SER 1036 
215 1 Y 1 A PHE 1037 ? A PHE 1037 
216 1 Y 1 A PRO 1038 ? A PRO 1038 
217 1 Y 1 A SER 1039 ? A SER 1039 
218 1 Y 1 A ALA 1040 ? A ALA 1040 
219 1 Y 1 A TYR 1041 ? A TYR 1041 
220 1 Y 1 A ASP 1042 ? A ASP 1042 
221 1 Y 1 A GLN 1043 ? A GLN 1043 
222 1 Y 1 A GLN 1044 ? A GLN 1044 
223 1 Y 1 A SER 1045 ? A SER 1045 
224 1 Y 1 A SER 1046 ? A SER 1046 
225 1 Y 1 A LYS 1047 ? A LYS 1047 
226 1 Y 1 A ASP 1048 ? A ASP 1048 
227 1 Y 1 A SER 1049 ? A SER 1049 
228 1 Y 1 A ARG 1050 ? A ARG 1050 
229 1 Y 1 A GLN 1051 ? A GLN 1051 
230 1 Y 1 A GLY 1052 ? A GLY 1052 
231 1 Y 1 C MET 1    ? B MET 1    
232 1 Y 1 C THR 2    ? B THR 2    
233 1 Y 1 C ARG 3    ? B ARG 3    
234 1 Y 1 C ASP 4    ? B ASP 4    
235 1 Y 1 C GLU 5    ? B GLU 5    
236 1 Y 1 C ALA 6    ? B ALA 6    
237 1 Y 1 C LEU 7    ? B LEU 7    
238 1 Y 1 C PRO 8    ? B PRO 8    
239 1 Y 1 C ASP 9    ? B ASP 9    
240 1 Y 1 C SER 10   ? B SER 10   
241 1 Y 1 C HIS 11   ? B HIS 11   
242 1 Y 1 C GLU 384  ? B GLU 384  
243 1 Y 1 C GLU 385  ? B GLU 385  
244 1 Y 1 C ASP 386  ? B ASP 386  
245 1 Y 1 C TYR 387  ? B TYR 387  
246 1 Y 1 D ASP -18  ? C ASP 1    
247 1 Y 1 D TYR -17  ? C TYR 2    
248 1 Y 1 D LYS -16  ? C LYS 3    
249 1 Y 1 D ASP -15  ? C ASP 4    
250 1 Y 1 D ASP -14  ? C ASP 5    
251 1 Y 1 D ASP -13  ? C ASP 6    
252 1 Y 1 D ASP -12  ? C ASP 7    
253 1 Y 1 D LYS -11  ? C LYS 8    
254 1 Y 1 D SER -10  ? C SER 9    
255 1 Y 1 D GLY -9   ? C GLY 10   
256 1 Y 1 D PRO -8   ? C PRO 11   
257 1 Y 1 D ASP -7   ? C ASP 12   
258 1 Y 1 D GLU -6   ? C GLU 13   
259 1 Y 1 D VAL -5   ? C VAL 14   
260 1 Y 1 D ASP -4   ? C ASP 15   
261 1 Y 1 D ALA -3   ? C ALA 16   
262 1 Y 1 D SER -2   ? C SER 17   
263 1 Y 1 D GLY -1   ? C GLY 18   
264 1 Y 1 D ARG 0    ? C ARG 19   
265 1 Y 1 D MET 1    ? C MET 20   
266 1 Y 1 D ALA 2    ? C ALA 21   
267 1 Y 1 D ASP 3    ? C ASP 22   
268 1 Y 1 D ILE 101  ? C ILE 120  
269 1 Y 1 D SER 102  ? C SER 121  
270 1 Y 1 D ALA 103  ? C ALA 122  
271 1 Y 1 D ALA 104  ? C ALA 123  
272 1 Y 1 D GLU 105  ? C GLU 124  
273 1 Y 1 D LEU 106  ? C LEU 125  
274 1 Y 1 D ARG 107  ? C ARG 126  
275 1 Y 1 D HIS 108  ? C HIS 127  
276 1 Y 1 D VAL 109  ? C VAL 128  
277 1 Y 1 D MET 110  ? C MET 129  
278 1 Y 1 D THR 111  ? C THR 130  
279 1 Y 1 D ASN 112  ? C ASN 131  
280 1 Y 1 D LEU 113  ? C LEU 132  
281 1 Y 1 D GLY 114  ? C GLY 133  
282 1 Y 1 D GLU 115  ? C GLU 134  
283 1 Y 1 D LYS 116  ? C LYS 135  
284 1 Y 1 D LEU 117  ? C LEU 136  
285 1 Y 1 D THR 118  ? C THR 137  
286 1 Y 1 D ASP 119  ? C ASP 138  
287 1 Y 1 D GLU 120  ? C GLU 139  
288 1 Y 1 D GLU 121  ? C GLU 140  
289 1 Y 1 D VAL 122  ? C VAL 141  
290 1 Y 1 D ASP 123  ? C ASP 142  
291 1 Y 1 D GLU 124  ? C GLU 143  
292 1 Y 1 D MET 125  ? C MET 144  
293 1 Y 1 D ILE 126  ? C ILE 145  
294 1 Y 1 D ARG 127  ? C ARG 146  
295 1 Y 1 D GLU 128  ? C GLU 147  
296 1 Y 1 D ALA 129  ? C ALA 148  
297 1 Y 1 D ASP 130  ? C ASP 149  
298 1 Y 1 D ILE 131  ? C ILE 150  
299 1 Y 1 D ASP 132  ? C ASP 151  
300 1 Y 1 D GLY 133  ? C GLY 152  
301 1 Y 1 D ASP 134  ? C ASP 153  
302 1 Y 1 D GLY 135  ? C GLY 154  
303 1 Y 1 D GLN 136  ? C GLN 155  
304 1 Y 1 D VAL 137  ? C VAL 156  
305 1 Y 1 D ASN 138  ? C ASN 157  
306 1 Y 1 D TYR 139  ? C TYR 158  
307 1 Y 1 D GLU 140  ? C GLU 159  
308 1 Y 1 D GLU 141  ? C GLU 160  
309 1 Y 1 D PHE 142  ? C PHE 161  
310 1 Y 1 D VAL 143  ? C VAL 162  
311 1 Y 1 D GLN 144  ? C GLN 163  
312 1 Y 1 D MET 145  ? C MET 164  
313 1 Y 1 D MET 146  ? C MET 165  
314 1 Y 1 D THR 147  ? C THR 166  
315 1 Y 1 D ALA 148  ? C ALA 167  
316 1 Y 1 D LYS 149  ? C LYS 168  
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N      N N N 1   
ALA CA     C N S 2   
ALA C      C N N 3   
ALA O      O N N 4   
ALA CB     C N N 5   
ALA OXT    O N N 6   
ALA H      H N N 7   
ALA H2     H N N 8   
ALA HA     H N N 9   
ALA HB1    H N N 10  
ALA HB2    H N N 11  
ALA HB3    H N N 12  
ALA HXT    H N N 13  
ARG N      N N N 14  
ARG CA     C N S 15  
ARG C      C N N 16  
ARG O      O N N 17  
ARG CB     C N N 18  
ARG CG     C N N 19  
ARG CD     C N N 20  
ARG NE     N N N 21  
ARG CZ     C N N 22  
ARG NH1    N N N 23  
ARG NH2    N N N 24  
ARG OXT    O N N 25  
ARG H      H N N 26  
ARG H2     H N N 27  
ARG HA     H N N 28  
ARG HB2    H N N 29  
ARG HB3    H N N 30  
ARG HG2    H N N 31  
ARG HG3    H N N 32  
ARG HD2    H N N 33  
ARG HD3    H N N 34  
ARG HE     H N N 35  
ARG HH11   H N N 36  
ARG HH12   H N N 37  
ARG HH21   H N N 38  
ARG HH22   H N N 39  
ARG HXT    H N N 40  
ASN N      N N N 41  
ASN CA     C N S 42  
ASN C      C N N 43  
ASN O      O N N 44  
ASN CB     C N N 45  
ASN CG     C N N 46  
ASN OD1    O N N 47  
ASN ND2    N N N 48  
ASN OXT    O N N 49  
ASN H      H N N 50  
ASN H2     H N N 51  
ASN HA     H N N 52  
ASN HB2    H N N 53  
ASN HB3    H N N 54  
ASN HD21   H N N 55  
ASN HD22   H N N 56  
ASN HXT    H N N 57  
ASP N      N N N 58  
ASP CA     C N S 59  
ASP C      C N N 60  
ASP O      O N N 61  
ASP CB     C N N 62  
ASP CG     C N N 63  
ASP OD1    O N N 64  
ASP OD2    O N N 65  
ASP OXT    O N N 66  
ASP H      H N N 67  
ASP H2     H N N 68  
ASP HA     H N N 69  
ASP HB2    H N N 70  
ASP HB3    H N N 71  
ASP HD2    H N N 72  
ASP HXT    H N N 73  
ATP PG     P N N 74  
ATP O1G    O N N 75  
ATP O2G    O N N 76  
ATP O3G    O N N 77  
ATP PB     P N R 78  
ATP O1B    O N N 79  
ATP O2B    O N N 80  
ATP O3B    O N N 81  
ATP PA     P N R 82  
ATP O1A    O N N 83  
ATP O2A    O N N 84  
ATP O3A    O N N 85  
ATP "O5'"  O N N 86  
ATP "C5'"  C N N 87  
ATP "C4'"  C N R 88  
ATP "O4'"  O N N 89  
ATP "C3'"  C N S 90  
ATP "O3'"  O N N 91  
ATP "C2'"  C N R 92  
ATP "O2'"  O N N 93  
ATP "C1'"  C N R 94  
ATP N9     N Y N 95  
ATP C8     C Y N 96  
ATP N7     N Y N 97  
ATP C5     C Y N 98  
ATP C6     C Y N 99  
ATP N6     N N N 100 
ATP N1     N Y N 101 
ATP C2     C Y N 102 
ATP N3     N Y N 103 
ATP C4     C Y N 104 
ATP HOG2   H N N 105 
ATP HOG3   H N N 106 
ATP HOB2   H N N 107 
ATP HOA2   H N N 108 
ATP "H5'1" H N N 109 
ATP "H5'2" H N N 110 
ATP "H4'"  H N N 111 
ATP "H3'"  H N N 112 
ATP "HO3'" H N N 113 
ATP "H2'"  H N N 114 
ATP "HO2'" H N N 115 
ATP "H1'"  H N N 116 
ATP H8     H N N 117 
ATP HN61   H N N 118 
ATP HN62   H N N 119 
ATP H2     H N N 120 
CYS N      N N N 121 
CYS CA     C N R 122 
CYS C      C N N 123 
CYS O      O N N 124 
CYS CB     C N N 125 
CYS SG     S N N 126 
CYS OXT    O N N 127 
CYS H      H N N 128 
CYS H2     H N N 129 
CYS HA     H N N 130 
CYS HB2    H N N 131 
CYS HB3    H N N 132 
CYS HG     H N N 133 
CYS HXT    H N N 134 
GLN N      N N N 135 
GLN CA     C N S 136 
GLN C      C N N 137 
GLN O      O N N 138 
GLN CB     C N N 139 
GLN CG     C N N 140 
GLN CD     C N N 141 
GLN OE1    O N N 142 
GLN NE2    N N N 143 
GLN OXT    O N N 144 
GLN H      H N N 145 
GLN H2     H N N 146 
GLN HA     H N N 147 
GLN HB2    H N N 148 
GLN HB3    H N N 149 
GLN HG2    H N N 150 
GLN HG3    H N N 151 
GLN HE21   H N N 152 
GLN HE22   H N N 153 
GLN HXT    H N N 154 
GLU N      N N N 155 
GLU CA     C N S 156 
GLU C      C N N 157 
GLU O      O N N 158 
GLU CB     C N N 159 
GLU CG     C N N 160 
GLU CD     C N N 161 
GLU OE1    O N N 162 
GLU OE2    O N N 163 
GLU OXT    O N N 164 
GLU H      H N N 165 
GLU H2     H N N 166 
GLU HA     H N N 167 
GLU HB2    H N N 168 
GLU HB3    H N N 169 
GLU HG2    H N N 170 
GLU HG3    H N N 171 
GLU HE2    H N N 172 
GLU HXT    H N N 173 
GLY N      N N N 174 
GLY CA     C N N 175 
GLY C      C N N 176 
GLY O      O N N 177 
GLY OXT    O N N 178 
GLY H      H N N 179 
GLY H2     H N N 180 
GLY HA2    H N N 181 
GLY HA3    H N N 182 
GLY HXT    H N N 183 
HIS N      N N N 184 
HIS CA     C N S 185 
HIS C      C N N 186 
HIS O      O N N 187 
HIS CB     C N N 188 
HIS CG     C Y N 189 
HIS ND1    N Y N 190 
HIS CD2    C Y N 191 
HIS CE1    C Y N 192 
HIS NE2    N Y N 193 
HIS OXT    O N N 194 
HIS H      H N N 195 
HIS H2     H N N 196 
HIS HA     H N N 197 
HIS HB2    H N N 198 
HIS HB3    H N N 199 
HIS HD1    H N N 200 
HIS HD2    H N N 201 
HIS HE1    H N N 202 
HIS HE2    H N N 203 
HIS HXT    H N N 204 
ILE N      N N N 205 
ILE CA     C N S 206 
ILE C      C N N 207 
ILE O      O N N 208 
ILE CB     C N S 209 
ILE CG1    C N N 210 
ILE CG2    C N N 211 
ILE CD1    C N N 212 
ILE OXT    O N N 213 
ILE H      H N N 214 
ILE H2     H N N 215 
ILE HA     H N N 216 
ILE HB     H N N 217 
ILE HG12   H N N 218 
ILE HG13   H N N 219 
ILE HG21   H N N 220 
ILE HG22   H N N 221 
ILE HG23   H N N 222 
ILE HD11   H N N 223 
ILE HD12   H N N 224 
ILE HD13   H N N 225 
ILE HXT    H N N 226 
LEU N      N N N 227 
LEU CA     C N S 228 
LEU C      C N N 229 
LEU O      O N N 230 
LEU CB     C N N 231 
LEU CG     C N N 232 
LEU CD1    C N N 233 
LEU CD2    C N N 234 
LEU OXT    O N N 235 
LEU H      H N N 236 
LEU H2     H N N 237 
LEU HA     H N N 238 
LEU HB2    H N N 239 
LEU HB3    H N N 240 
LEU HG     H N N 241 
LEU HD11   H N N 242 
LEU HD12   H N N 243 
LEU HD13   H N N 244 
LEU HD21   H N N 245 
LEU HD22   H N N 246 
LEU HD23   H N N 247 
LEU HXT    H N N 248 
LYS N      N N N 249 
LYS CA     C N S 250 
LYS C      C N N 251 
LYS O      O N N 252 
LYS CB     C N N 253 
LYS CG     C N N 254 
LYS CD     C N N 255 
LYS CE     C N N 256 
LYS NZ     N N N 257 
LYS OXT    O N N 258 
LYS H      H N N 259 
LYS H2     H N N 260 
LYS HA     H N N 261 
LYS HB2    H N N 262 
LYS HB3    H N N 263 
LYS HG2    H N N 264 
LYS HG3    H N N 265 
LYS HD2    H N N 266 
LYS HD3    H N N 267 
LYS HE2    H N N 268 
LYS HE3    H N N 269 
LYS HZ1    H N N 270 
LYS HZ2    H N N 271 
LYS HZ3    H N N 272 
LYS HXT    H N N 273 
MET N      N N N 274 
MET CA     C N S 275 
MET C      C N N 276 
MET O      O N N 277 
MET CB     C N N 278 
MET CG     C N N 279 
MET SD     S N N 280 
MET CE     C N N 281 
MET OXT    O N N 282 
MET H      H N N 283 
MET H2     H N N 284 
MET HA     H N N 285 
MET HB2    H N N 286 
MET HB3    H N N 287 
MET HG2    H N N 288 
MET HG3    H N N 289 
MET HE1    H N N 290 
MET HE2    H N N 291 
MET HE3    H N N 292 
MET HXT    H N N 293 
PHE N      N N N 294 
PHE CA     C N S 295 
PHE C      C N N 296 
PHE O      O N N 297 
PHE CB     C N N 298 
PHE CG     C Y N 299 
PHE CD1    C Y N 300 
PHE CD2    C Y N 301 
PHE CE1    C Y N 302 
PHE CE2    C Y N 303 
PHE CZ     C Y N 304 
PHE OXT    O N N 305 
PHE H      H N N 306 
PHE H2     H N N 307 
PHE HA     H N N 308 
PHE HB2    H N N 309 
PHE HB3    H N N 310 
PHE HD1    H N N 311 
PHE HD2    H N N 312 
PHE HE1    H N N 313 
PHE HE2    H N N 314 
PHE HZ     H N N 315 
PHE HXT    H N N 316 
PRO N      N N N 317 
PRO CA     C N S 318 
PRO C      C N N 319 
PRO O      O N N 320 
PRO CB     C N N 321 
PRO CG     C N N 322 
PRO CD     C N N 323 
PRO OXT    O N N 324 
PRO H      H N N 325 
PRO HA     H N N 326 
PRO HB2    H N N 327 
PRO HB3    H N N 328 
PRO HG2    H N N 329 
PRO HG3    H N N 330 
PRO HD2    H N N 331 
PRO HD3    H N N 332 
PRO HXT    H N N 333 
SEP N      N N N 334 
SEP CA     C N S 335 
SEP CB     C N N 336 
SEP OG     O N N 337 
SEP C      C N N 338 
SEP O      O N N 339 
SEP OXT    O N N 340 
SEP P      P N N 341 
SEP O1P    O N N 342 
SEP O2P    O N N 343 
SEP O3P    O N N 344 
SEP H      H N N 345 
SEP H2     H N N 346 
SEP HA     H N N 347 
SEP HB2    H N N 348 
SEP HB3    H N N 349 
SEP HXT    H N N 350 
SEP HOP2   H N N 351 
SEP HOP3   H N N 352 
SER N      N N N 353 
SER CA     C N S 354 
SER C      C N N 355 
SER O      O N N 356 
SER CB     C N N 357 
SER OG     O N N 358 
SER OXT    O N N 359 
SER H      H N N 360 
SER H2     H N N 361 
SER HA     H N N 362 
SER HB2    H N N 363 
SER HB3    H N N 364 
SER HG     H N N 365 
SER HXT    H N N 366 
THR N      N N N 367 
THR CA     C N S 368 
THR C      C N N 369 
THR O      O N N 370 
THR CB     C N R 371 
THR OG1    O N N 372 
THR CG2    C N N 373 
THR OXT    O N N 374 
THR H      H N N 375 
THR H2     H N N 376 
THR HA     H N N 377 
THR HB     H N N 378 
THR HG1    H N N 379 
THR HG21   H N N 380 
THR HG22   H N N 381 
THR HG23   H N N 382 
THR HXT    H N N 383 
TPO N      N N N 384 
TPO CA     C N S 385 
TPO CB     C N R 386 
TPO CG2    C N N 387 
TPO OG1    O N N 388 
TPO P      P N N 389 
TPO O1P    O N N 390 
TPO O2P    O N N 391 
TPO O3P    O N N 392 
TPO C      C N N 393 
TPO O      O N N 394 
TPO OXT    O N N 395 
TPO H      H N N 396 
TPO H2     H N N 397 
TPO HA     H N N 398 
TPO HB     H N N 399 
TPO HG21   H N N 400 
TPO HG22   H N N 401 
TPO HG23   H N N 402 
TPO HOP2   H N N 403 
TPO HOP3   H N N 404 
TPO HXT    H N N 405 
TRP N      N N N 406 
TRP CA     C N S 407 
TRP C      C N N 408 
TRP O      O N N 409 
TRP CB     C N N 410 
TRP CG     C Y N 411 
TRP CD1    C Y N 412 
TRP CD2    C Y N 413 
TRP NE1    N Y N 414 
TRP CE2    C Y N 415 
TRP CE3    C Y N 416 
TRP CZ2    C Y N 417 
TRP CZ3    C Y N 418 
TRP CH2    C Y N 419 
TRP OXT    O N N 420 
TRP H      H N N 421 
TRP H2     H N N 422 
TRP HA     H N N 423 
TRP HB2    H N N 424 
TRP HB3    H N N 425 
TRP HD1    H N N 426 
TRP HE1    H N N 427 
TRP HE3    H N N 428 
TRP HZ2    H N N 429 
TRP HZ3    H N N 430 
TRP HH2    H N N 431 
TRP HXT    H N N 432 
TYR N      N N N 433 
TYR CA     C N S 434 
TYR C      C N N 435 
TYR O      O N N 436 
TYR CB     C N N 437 
TYR CG     C Y N 438 
TYR CD1    C Y N 439 
TYR CD2    C Y N 440 
TYR CE1    C Y N 441 
TYR CE2    C Y N 442 
TYR CZ     C Y N 443 
TYR OH     O N N 444 
TYR OXT    O N N 445 
TYR H      H N N 446 
TYR H2     H N N 447 
TYR HA     H N N 448 
TYR HB2    H N N 449 
TYR HB3    H N N 450 
TYR HD1    H N N 451 
TYR HD2    H N N 452 
TYR HE1    H N N 453 
TYR HE2    H N N 454 
TYR HH     H N N 455 
TYR HXT    H N N 456 
VAL N      N N N 457 
VAL CA     C N S 458 
VAL C      C N N 459 
VAL O      O N N 460 
VAL CB     C N N 461 
VAL CG1    C N N 462 
VAL CG2    C N N 463 
VAL OXT    O N N 464 
VAL H      H N N 465 
VAL H2     H N N 466 
VAL HA     H N N 467 
VAL HB     H N N 468 
VAL HG11   H N N 469 
VAL HG12   H N N 470 
VAL HG13   H N N 471 
VAL HG21   H N N 472 
VAL HG22   H N N 473 
VAL HG23   H N N 474 
VAL HXT    H N N 475 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N     CA     sing N N 1   
ALA N     H      sing N N 2   
ALA N     H2     sing N N 3   
ALA CA    C      sing N N 4   
ALA CA    CB     sing N N 5   
ALA CA    HA     sing N N 6   
ALA C     O      doub N N 7   
ALA C     OXT    sing N N 8   
ALA CB    HB1    sing N N 9   
ALA CB    HB2    sing N N 10  
ALA CB    HB3    sing N N 11  
ALA OXT   HXT    sing N N 12  
ARG N     CA     sing N N 13  
ARG N     H      sing N N 14  
ARG N     H2     sing N N 15  
ARG CA    C      sing N N 16  
ARG CA    CB     sing N N 17  
ARG CA    HA     sing N N 18  
ARG C     O      doub N N 19  
ARG C     OXT    sing N N 20  
ARG CB    CG     sing N N 21  
ARG CB    HB2    sing N N 22  
ARG CB    HB3    sing N N 23  
ARG CG    CD     sing N N 24  
ARG CG    HG2    sing N N 25  
ARG CG    HG3    sing N N 26  
ARG CD    NE     sing N N 27  
ARG CD    HD2    sing N N 28  
ARG CD    HD3    sing N N 29  
ARG NE    CZ     sing N N 30  
ARG NE    HE     sing N N 31  
ARG CZ    NH1    sing N N 32  
ARG CZ    NH2    doub N N 33  
ARG NH1   HH11   sing N N 34  
ARG NH1   HH12   sing N N 35  
ARG NH2   HH21   sing N N 36  
ARG NH2   HH22   sing N N 37  
ARG OXT   HXT    sing N N 38  
ASN N     CA     sing N N 39  
ASN N     H      sing N N 40  
ASN N     H2     sing N N 41  
ASN CA    C      sing N N 42  
ASN CA    CB     sing N N 43  
ASN CA    HA     sing N N 44  
ASN C     O      doub N N 45  
ASN C     OXT    sing N N 46  
ASN CB    CG     sing N N 47  
ASN CB    HB2    sing N N 48  
ASN CB    HB3    sing N N 49  
ASN CG    OD1    doub N N 50  
ASN CG    ND2    sing N N 51  
ASN ND2   HD21   sing N N 52  
ASN ND2   HD22   sing N N 53  
ASN OXT   HXT    sing N N 54  
ASP N     CA     sing N N 55  
ASP N     H      sing N N 56  
ASP N     H2     sing N N 57  
ASP CA    C      sing N N 58  
ASP CA    CB     sing N N 59  
ASP CA    HA     sing N N 60  
ASP C     O      doub N N 61  
ASP C     OXT    sing N N 62  
ASP CB    CG     sing N N 63  
ASP CB    HB2    sing N N 64  
ASP CB    HB3    sing N N 65  
ASP CG    OD1    doub N N 66  
ASP CG    OD2    sing N N 67  
ASP OD2   HD2    sing N N 68  
ASP OXT   HXT    sing N N 69  
ATP PG    O1G    doub N N 70  
ATP PG    O2G    sing N N 71  
ATP PG    O3G    sing N N 72  
ATP PG    O3B    sing N N 73  
ATP O2G   HOG2   sing N N 74  
ATP O3G   HOG3   sing N N 75  
ATP PB    O1B    doub N N 76  
ATP PB    O2B    sing N N 77  
ATP PB    O3B    sing N N 78  
ATP PB    O3A    sing N N 79  
ATP O2B   HOB2   sing N N 80  
ATP PA    O1A    doub N N 81  
ATP PA    O2A    sing N N 82  
ATP PA    O3A    sing N N 83  
ATP PA    "O5'"  sing N N 84  
ATP O2A   HOA2   sing N N 85  
ATP "O5'" "C5'"  sing N N 86  
ATP "C5'" "C4'"  sing N N 87  
ATP "C5'" "H5'1" sing N N 88  
ATP "C5'" "H5'2" sing N N 89  
ATP "C4'" "O4'"  sing N N 90  
ATP "C4'" "C3'"  sing N N 91  
ATP "C4'" "H4'"  sing N N 92  
ATP "O4'" "C1'"  sing N N 93  
ATP "C3'" "O3'"  sing N N 94  
ATP "C3'" "C2'"  sing N N 95  
ATP "C3'" "H3'"  sing N N 96  
ATP "O3'" "HO3'" sing N N 97  
ATP "C2'" "O2'"  sing N N 98  
ATP "C2'" "C1'"  sing N N 99  
ATP "C2'" "H2'"  sing N N 100 
ATP "O2'" "HO2'" sing N N 101 
ATP "C1'" N9     sing N N 102 
ATP "C1'" "H1'"  sing N N 103 
ATP N9    C8     sing Y N 104 
ATP N9    C4     sing Y N 105 
ATP C8    N7     doub Y N 106 
ATP C8    H8     sing N N 107 
ATP N7    C5     sing Y N 108 
ATP C5    C6     sing Y N 109 
ATP C5    C4     doub Y N 110 
ATP C6    N6     sing N N 111 
ATP C6    N1     doub Y N 112 
ATP N6    HN61   sing N N 113 
ATP N6    HN62   sing N N 114 
ATP N1    C2     sing Y N 115 
ATP C2    N3     doub Y N 116 
ATP C2    H2     sing N N 117 
ATP N3    C4     sing Y N 118 
CYS N     CA     sing N N 119 
CYS N     H      sing N N 120 
CYS N     H2     sing N N 121 
CYS CA    C      sing N N 122 
CYS CA    CB     sing N N 123 
CYS CA    HA     sing N N 124 
CYS C     O      doub N N 125 
CYS C     OXT    sing N N 126 
CYS CB    SG     sing N N 127 
CYS CB    HB2    sing N N 128 
CYS CB    HB3    sing N N 129 
CYS SG    HG     sing N N 130 
CYS OXT   HXT    sing N N 131 
GLN N     CA     sing N N 132 
GLN N     H      sing N N 133 
GLN N     H2     sing N N 134 
GLN CA    C      sing N N 135 
GLN CA    CB     sing N N 136 
GLN CA    HA     sing N N 137 
GLN C     O      doub N N 138 
GLN C     OXT    sing N N 139 
GLN CB    CG     sing N N 140 
GLN CB    HB2    sing N N 141 
GLN CB    HB3    sing N N 142 
GLN CG    CD     sing N N 143 
GLN CG    HG2    sing N N 144 
GLN CG    HG3    sing N N 145 
GLN CD    OE1    doub N N 146 
GLN CD    NE2    sing N N 147 
GLN NE2   HE21   sing N N 148 
GLN NE2   HE22   sing N N 149 
GLN OXT   HXT    sing N N 150 
GLU N     CA     sing N N 151 
GLU N     H      sing N N 152 
GLU N     H2     sing N N 153 
GLU CA    C      sing N N 154 
GLU CA    CB     sing N N 155 
GLU CA    HA     sing N N 156 
GLU C     O      doub N N 157 
GLU C     OXT    sing N N 158 
GLU CB    CG     sing N N 159 
GLU CB    HB2    sing N N 160 
GLU CB    HB3    sing N N 161 
GLU CG    CD     sing N N 162 
GLU CG    HG2    sing N N 163 
GLU CG    HG3    sing N N 164 
GLU CD    OE1    doub N N 165 
GLU CD    OE2    sing N N 166 
GLU OE2   HE2    sing N N 167 
GLU OXT   HXT    sing N N 168 
GLY N     CA     sing N N 169 
GLY N     H      sing N N 170 
GLY N     H2     sing N N 171 
GLY CA    C      sing N N 172 
GLY CA    HA2    sing N N 173 
GLY CA    HA3    sing N N 174 
GLY C     O      doub N N 175 
GLY C     OXT    sing N N 176 
GLY OXT   HXT    sing N N 177 
HIS N     CA     sing N N 178 
HIS N     H      sing N N 179 
HIS N     H2     sing N N 180 
HIS CA    C      sing N N 181 
HIS CA    CB     sing N N 182 
HIS CA    HA     sing N N 183 
HIS C     O      doub N N 184 
HIS C     OXT    sing N N 185 
HIS CB    CG     sing N N 186 
HIS CB    HB2    sing N N 187 
HIS CB    HB3    sing N N 188 
HIS CG    ND1    sing Y N 189 
HIS CG    CD2    doub Y N 190 
HIS ND1   CE1    doub Y N 191 
HIS ND1   HD1    sing N N 192 
HIS CD2   NE2    sing Y N 193 
HIS CD2   HD2    sing N N 194 
HIS CE1   NE2    sing Y N 195 
HIS CE1   HE1    sing N N 196 
HIS NE2   HE2    sing N N 197 
HIS OXT   HXT    sing N N 198 
ILE N     CA     sing N N 199 
ILE N     H      sing N N 200 
ILE N     H2     sing N N 201 
ILE CA    C      sing N N 202 
ILE CA    CB     sing N N 203 
ILE CA    HA     sing N N 204 
ILE C     O      doub N N 205 
ILE C     OXT    sing N N 206 
ILE CB    CG1    sing N N 207 
ILE CB    CG2    sing N N 208 
ILE CB    HB     sing N N 209 
ILE CG1   CD1    sing N N 210 
ILE CG1   HG12   sing N N 211 
ILE CG1   HG13   sing N N 212 
ILE CG2   HG21   sing N N 213 
ILE CG2   HG22   sing N N 214 
ILE CG2   HG23   sing N N 215 
ILE CD1   HD11   sing N N 216 
ILE CD1   HD12   sing N N 217 
ILE CD1   HD13   sing N N 218 
ILE OXT   HXT    sing N N 219 
LEU N     CA     sing N N 220 
LEU N     H      sing N N 221 
LEU N     H2     sing N N 222 
LEU CA    C      sing N N 223 
LEU CA    CB     sing N N 224 
LEU CA    HA     sing N N 225 
LEU C     O      doub N N 226 
LEU C     OXT    sing N N 227 
LEU CB    CG     sing N N 228 
LEU CB    HB2    sing N N 229 
LEU CB    HB3    sing N N 230 
LEU CG    CD1    sing N N 231 
LEU CG    CD2    sing N N 232 
LEU CG    HG     sing N N 233 
LEU CD1   HD11   sing N N 234 
LEU CD1   HD12   sing N N 235 
LEU CD1   HD13   sing N N 236 
LEU CD2   HD21   sing N N 237 
LEU CD2   HD22   sing N N 238 
LEU CD2   HD23   sing N N 239 
LEU OXT   HXT    sing N N 240 
LYS N     CA     sing N N 241 
LYS N     H      sing N N 242 
LYS N     H2     sing N N 243 
LYS CA    C      sing N N 244 
LYS CA    CB     sing N N 245 
LYS CA    HA     sing N N 246 
LYS C     O      doub N N 247 
LYS C     OXT    sing N N 248 
LYS CB    CG     sing N N 249 
LYS CB    HB2    sing N N 250 
LYS CB    HB3    sing N N 251 
LYS CG    CD     sing N N 252 
LYS CG    HG2    sing N N 253 
LYS CG    HG3    sing N N 254 
LYS CD    CE     sing N N 255 
LYS CD    HD2    sing N N 256 
LYS CD    HD3    sing N N 257 
LYS CE    NZ     sing N N 258 
LYS CE    HE2    sing N N 259 
LYS CE    HE3    sing N N 260 
LYS NZ    HZ1    sing N N 261 
LYS NZ    HZ2    sing N N 262 
LYS NZ    HZ3    sing N N 263 
LYS OXT   HXT    sing N N 264 
MET N     CA     sing N N 265 
MET N     H      sing N N 266 
MET N     H2     sing N N 267 
MET CA    C      sing N N 268 
MET CA    CB     sing N N 269 
MET CA    HA     sing N N 270 
MET C     O      doub N N 271 
MET C     OXT    sing N N 272 
MET CB    CG     sing N N 273 
MET CB    HB2    sing N N 274 
MET CB    HB3    sing N N 275 
MET CG    SD     sing N N 276 
MET CG    HG2    sing N N 277 
MET CG    HG3    sing N N 278 
MET SD    CE     sing N N 279 
MET CE    HE1    sing N N 280 
MET CE    HE2    sing N N 281 
MET CE    HE3    sing N N 282 
MET OXT   HXT    sing N N 283 
PHE N     CA     sing N N 284 
PHE N     H      sing N N 285 
PHE N     H2     sing N N 286 
PHE CA    C      sing N N 287 
PHE CA    CB     sing N N 288 
PHE CA    HA     sing N N 289 
PHE C     O      doub N N 290 
PHE C     OXT    sing N N 291 
PHE CB    CG     sing N N 292 
PHE CB    HB2    sing N N 293 
PHE CB    HB3    sing N N 294 
PHE CG    CD1    doub Y N 295 
PHE CG    CD2    sing Y N 296 
PHE CD1   CE1    sing Y N 297 
PHE CD1   HD1    sing N N 298 
PHE CD2   CE2    doub Y N 299 
PHE CD2   HD2    sing N N 300 
PHE CE1   CZ     doub Y N 301 
PHE CE1   HE1    sing N N 302 
PHE CE2   CZ     sing Y N 303 
PHE CE2   HE2    sing N N 304 
PHE CZ    HZ     sing N N 305 
PHE OXT   HXT    sing N N 306 
PRO N     CA     sing N N 307 
PRO N     CD     sing N N 308 
PRO N     H      sing N N 309 
PRO CA    C      sing N N 310 
PRO CA    CB     sing N N 311 
PRO CA    HA     sing N N 312 
PRO C     O      doub N N 313 
PRO C     OXT    sing N N 314 
PRO CB    CG     sing N N 315 
PRO CB    HB2    sing N N 316 
PRO CB    HB3    sing N N 317 
PRO CG    CD     sing N N 318 
PRO CG    HG2    sing N N 319 
PRO CG    HG3    sing N N 320 
PRO CD    HD2    sing N N 321 
PRO CD    HD3    sing N N 322 
PRO OXT   HXT    sing N N 323 
SEP N     CA     sing N N 324 
SEP N     H      sing N N 325 
SEP N     H2     sing N N 326 
SEP CA    CB     sing N N 327 
SEP CA    C      sing N N 328 
SEP CA    HA     sing N N 329 
SEP CB    OG     sing N N 330 
SEP CB    HB2    sing N N 331 
SEP CB    HB3    sing N N 332 
SEP OG    P      sing N N 333 
SEP C     O      doub N N 334 
SEP C     OXT    sing N N 335 
SEP OXT   HXT    sing N N 336 
SEP P     O1P    doub N N 337 
SEP P     O2P    sing N N 338 
SEP P     O3P    sing N N 339 
SEP O2P   HOP2   sing N N 340 
SEP O3P   HOP3   sing N N 341 
SER N     CA     sing N N 342 
SER N     H      sing N N 343 
SER N     H2     sing N N 344 
SER CA    C      sing N N 345 
SER CA    CB     sing N N 346 
SER CA    HA     sing N N 347 
SER C     O      doub N N 348 
SER C     OXT    sing N N 349 
SER CB    OG     sing N N 350 
SER CB    HB2    sing N N 351 
SER CB    HB3    sing N N 352 
SER OG    HG     sing N N 353 
SER OXT   HXT    sing N N 354 
THR N     CA     sing N N 355 
THR N     H      sing N N 356 
THR N     H2     sing N N 357 
THR CA    C      sing N N 358 
THR CA    CB     sing N N 359 
THR CA    HA     sing N N 360 
THR C     O      doub N N 361 
THR C     OXT    sing N N 362 
THR CB    OG1    sing N N 363 
THR CB    CG2    sing N N 364 
THR CB    HB     sing N N 365 
THR OG1   HG1    sing N N 366 
THR CG2   HG21   sing N N 367 
THR CG2   HG22   sing N N 368 
THR CG2   HG23   sing N N 369 
THR OXT   HXT    sing N N 370 
TPO N     CA     sing N N 371 
TPO N     H      sing N N 372 
TPO N     H2     sing N N 373 
TPO CA    CB     sing N N 374 
TPO CA    C      sing N N 375 
TPO CA    HA     sing N N 376 
TPO CB    CG2    sing N N 377 
TPO CB    OG1    sing N N 378 
TPO CB    HB     sing N N 379 
TPO CG2   HG21   sing N N 380 
TPO CG2   HG22   sing N N 381 
TPO CG2   HG23   sing N N 382 
TPO OG1   P      sing N N 383 
TPO P     O1P    doub N N 384 
TPO P     O2P    sing N N 385 
TPO P     O3P    sing N N 386 
TPO O2P   HOP2   sing N N 387 
TPO O3P   HOP3   sing N N 388 
TPO C     O      doub N N 389 
TPO C     OXT    sing N N 390 
TPO OXT   HXT    sing N N 391 
TRP N     CA     sing N N 392 
TRP N     H      sing N N 393 
TRP N     H2     sing N N 394 
TRP CA    C      sing N N 395 
TRP CA    CB     sing N N 396 
TRP CA    HA     sing N N 397 
TRP C     O      doub N N 398 
TRP C     OXT    sing N N 399 
TRP CB    CG     sing N N 400 
TRP CB    HB2    sing N N 401 
TRP CB    HB3    sing N N 402 
TRP CG    CD1    doub Y N 403 
TRP CG    CD2    sing Y N 404 
TRP CD1   NE1    sing Y N 405 
TRP CD1   HD1    sing N N 406 
TRP CD2   CE2    doub Y N 407 
TRP CD2   CE3    sing Y N 408 
TRP NE1   CE2    sing Y N 409 
TRP NE1   HE1    sing N N 410 
TRP CE2   CZ2    sing Y N 411 
TRP CE3   CZ3    doub Y N 412 
TRP CE3   HE3    sing N N 413 
TRP CZ2   CH2    doub Y N 414 
TRP CZ2   HZ2    sing N N 415 
TRP CZ3   CH2    sing Y N 416 
TRP CZ3   HZ3    sing N N 417 
TRP CH2   HH2    sing N N 418 
TRP OXT   HXT    sing N N 419 
TYR N     CA     sing N N 420 
TYR N     H      sing N N 421 
TYR N     H2     sing N N 422 
TYR CA    C      sing N N 423 
TYR CA    CB     sing N N 424 
TYR CA    HA     sing N N 425 
TYR C     O      doub N N 426 
TYR C     OXT    sing N N 427 
TYR CB    CG     sing N N 428 
TYR CB    HB2    sing N N 429 
TYR CB    HB3    sing N N 430 
TYR CG    CD1    doub Y N 431 
TYR CG    CD2    sing Y N 432 
TYR CD1   CE1    sing Y N 433 
TYR CD1   HD1    sing N N 434 
TYR CD2   CE2    doub Y N 435 
TYR CD2   HD2    sing N N 436 
TYR CE1   CZ     doub Y N 437 
TYR CE1   HE1    sing N N 438 
TYR CE2   CZ     sing Y N 439 
TYR CE2   HE2    sing N N 440 
TYR CZ    OH     sing N N 441 
TYR OH    HH     sing N N 442 
TYR OXT   HXT    sing N N 443 
VAL N     CA     sing N N 444 
VAL N     H      sing N N 445 
VAL N     H2     sing N N 446 
VAL CA    C      sing N N 447 
VAL CA    CB     sing N N 448 
VAL CA    HA     sing N N 449 
VAL C     O      doub N N 450 
VAL C     OXT    sing N N 451 
VAL CB    CG1    sing N N 452 
VAL CB    CG2    sing N N 453 
VAL CB    HB     sing N N 454 
VAL CG1   HG11   sing N N 455 
VAL CG1   HG12   sing N N 456 
VAL CG1   HG13   sing N N 457 
VAL CG2   HG21   sing N N 458 
VAL CG2   HG22   sing N N 459 
VAL CG2   HG23   sing N N 460 
VAL OXT   HXT    sing N N 461 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-04-18 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           8Z5R 
_em_admin.last_update        2025-04-23 
_em_admin.map_release_date   2025-04-23 
_em_admin.title              'human phosphorylase kinase alpha/gamma/delta subcomplex - phosphorylation and Ca2+ bound state' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_molwt.entity_assembly_id   1 
_em_entity_assembly_molwt.experimental_flag    NO 
_em_entity_assembly_molwt.id                   1 
_em_entity_assembly_molwt.units                MEGADALTONS 
_em_entity_assembly_molwt.value                1.3 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          9606 
_em_entity_assembly_recombinant.organism             'Homo sapiens' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         50 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'MODEL REFINEMENT'              ? 1  ? ? ? PHENIX 1.20.1_4487: 
'IMAGE ACQUISITION'             ? 2  1 1 1 ?      ?            
'PARTICLE SELECTION'            ? 3  1 1 1 ?      ?            
'VOLUME SELECTION'              ? 4  1 1 1 ?      ?            
CLASSIFICATION                  ? 5  1 1 1 ?      ?            
MASKING                         ? 6  1 1 1 ?      ?            
RECONSTRUCTION                  ? 7  1 1 1 ?      ?            
'INITIAL EULER ASSIGNMENT'      ? 8  1 1 1 ?      ?            
'FINAL EULER ASSIGNMENT'        ? 9  1 1 1 ?      ?            
'CTF CORRECTION'                ? 10 1 1 1 ?      ?            
'LAYERLINE INDEXING'            ? 11 1 1 1 ?      ?            
'DIFFRACTION INDEXING'          ? 12 1 1 1 ?      ?            
'MODEL FITTING'                 ? 13 1 1 1 ?      ?            
'SERIES ALIGNMENT'              ? 14 1 1 1 ?      ?            
'MOLECULAR REPLACEMENT'         ? 15 1 1 1 ?      ?            
'LATTICE DISTORTION CORRECTION' ? 16 1 1 1 ?      ?            
'SYMMETRY DETERMINATION'        ? 17 1 1 1 ?      ?            
'CRYSTALLOGRAPHY MERGING'       ? 18 1 1 1 ?      ?            
OTHER                           ? 19 1 1 1 ?      ?            
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'National Natural Science Foundation of China (NSFC)' 
_pdbx_audit_support.country                China 
_pdbx_audit_support.grant_number           32271251 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    8Z5R 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
P 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1     N N     . SER A 1 5    ? 260.151 341.399 257.175 1.00 69.11  ? 5    SER A N     1 
ATOM   2     C CA    . SER A 1 5    ? 259.316 342.002 256.142 1.00 69.11  ? 5    SER A CA    1 
ATOM   3     C C     . SER A 1 5    ? 258.227 342.874 256.758 1.00 69.11  ? 5    SER A C     1 
ATOM   4     O O     . SER A 1 5    ? 257.727 342.582 257.844 1.00 69.11  ? 5    SER A O     1 
ATOM   5     C CB    . SER A 1 5    ? 258.689 340.919 255.261 1.00 69.11  ? 5    SER A CB    1 
ATOM   6     O OG    . SER A 1 5    ? 258.174 339.857 256.045 1.00 69.11  ? 5    SER A OG    1 
ATOM   7     N N     . ASN A 1 6    ? 257.868 343.951 256.054 1.00 66.30  ? 6    ASN A N     1 
ATOM   8     C CA    . ASN A 1 6    ? 256.822 344.843 256.544 1.00 66.30  ? 6    ASN A CA    1 
ATOM   9     C C     . ASN A 1 6    ? 255.478 344.129 256.624 1.00 66.30  ? 6    ASN A C     1 
ATOM   10    O O     . ASN A 1 6    ? 254.710 344.338 257.571 1.00 66.30  ? 6    ASN A O     1 
ATOM   11    C CB    . ASN A 1 6    ? 256.723 346.077 255.648 1.00 66.30  ? 6    ASN A CB    1 
ATOM   12    C CG    . ASN A 1 6    ? 256.001 347.229 256.319 1.00 66.30  ? 6    ASN A CG    1 
ATOM   13    O OD1   . ASN A 1 6    ? 256.065 347.390 257.538 1.00 66.30  ? 6    ASN A OD1   1 
ATOM   14    N ND2   . ASN A 1 6    ? 255.309 348.037 255.525 1.00 66.30  ? 6    ASN A ND2   1 
ATOM   15    N N     . SER A 1 7    ? 255.176 343.285 255.633 1.00 56.51  ? 7    SER A N     1 
ATOM   16    C CA    . SER A 1 7    ? 253.927 342.532 255.656 1.00 56.51  ? 7    SER A CA    1 
ATOM   17    C C     . SER A 1 7    ? 253.865 341.610 256.867 1.00 56.51  ? 7    SER A C     1 
ATOM   18    O O     . SER A 1 7    ? 252.804 341.452 257.483 1.00 56.51  ? 7    SER A O     1 
ATOM   19    C CB    . SER A 1 7    ? 253.771 341.732 254.362 1.00 56.51  ? 7    SER A CB    1 
ATOM   20    O OG    . SER A 1 7    ? 253.820 342.582 253.229 1.00 56.51  ? 7    SER A OG    1 
ATOM   21    N N     . GLY A 1 8    ? 254.993 340.992 257.222 1.00 55.01  ? 8    GLY A N     1 
ATOM   22    C CA    . GLY A 1 8    ? 255.028 340.172 258.421 1.00 55.01  ? 8    GLY A CA    1 
ATOM   23    C C     . GLY A 1 8    ? 254.752 340.970 259.681 1.00 55.01  ? 8    GLY A C     1 
ATOM   24    O O     . GLY A 1 8    ? 254.045 340.506 260.578 1.00 55.01  ? 8    GLY A O     1 
ATOM   25    N N     . VAL A 1 9    ? 255.303 342.184 259.764 1.00 54.75  ? 9    VAL A N     1 
ATOM   26    C CA    . VAL A 1 9    ? 255.058 343.037 260.924 1.00 54.75  ? 9    VAL A CA    1 
ATOM   27    C C     . VAL A 1 9    ? 253.585 343.423 261.003 1.00 54.75  ? 9    VAL A C     1 
ATOM   28    O O     . VAL A 1 9    ? 252.982 343.413 262.084 1.00 54.75  ? 9    VAL A O     1 
ATOM   29    C CB    . VAL A 1 9    ? 255.968 344.279 260.877 1.00 54.75  ? 9    VAL A CB    1 
ATOM   30    C CG1   . VAL A 1 9    ? 255.698 345.183 262.071 1.00 54.75  ? 9    VAL A CG1   1 
ATOM   31    C CG2   . VAL A 1 9    ? 257.430 343.862 260.840 1.00 54.75  ? 9    VAL A CG2   1 
ATOM   32    N N     . ARG A 1 10   ? 252.985 343.776 259.862 1.00 50.41  ? 10   ARG A N     1 
ATOM   33    C CA    . ARG A 1 10   ? 251.566 344.120 259.854 1.00 50.41  ? 10   ARG A CA    1 
ATOM   34    C C     . ARG A 1 10   ? 250.706 342.928 260.260 1.00 50.41  ? 10   ARG A C     1 
ATOM   35    O O     . ARG A 1 10   ? 249.737 343.079 261.015 1.00 50.41  ? 10   ARG A O     1 
ATOM   36    C CB    . ARG A 1 10   ? 251.154 344.634 258.474 1.00 50.41  ? 10   ARG A CB    1 
ATOM   37    C CG    . ARG A 1 10   ? 251.957 345.828 257.986 1.00 50.41  ? 10   ARG A CG    1 
ATOM   38    C CD    . ARG A 1 10   ? 251.829 347.013 258.934 1.00 50.41  ? 10   ARG A CD    1 
ATOM   39    N NE    . ARG A 1 10   ? 252.165 348.283 258.297 1.00 50.41  ? 10   ARG A NE    1 
ATOM   40    C CZ    . ARG A 1 10   ? 251.477 348.844 257.311 1.00 50.41  ? 10   ARG A CZ    1 
ATOM   41    N NH1   . ARG A 1 10   ? 250.372 348.294 256.834 1.00 50.41  ? 10   ARG A NH1   1 
ATOM   42    N NH2   . ARG A 1 10   ? 251.903 349.994 256.797 1.00 50.41  ? 10   ARG A NH2   1 
ATOM   43    N N     . LEU A 1 11   ? 251.043 341.734 259.766 1.00 43.50  ? 11   LEU A N     1 
ATOM   44    C CA    . LEU A 1 11   ? 250.291 340.541 260.139 1.00 43.50  ? 11   LEU A CA    1 
ATOM   45    C C     . LEU A 1 11   ? 250.438 340.237 261.624 1.00 43.50  ? 11   LEU A C     1 
ATOM   46    O O     . LEU A 1 11   ? 249.471 339.836 262.280 1.00 43.50  ? 11   LEU A O     1 
ATOM   47    C CB    . LEU A 1 11   ? 250.745 339.349 259.296 1.00 43.50  ? 11   LEU A CB    1 
ATOM   48    C CG    . LEU A 1 11   ? 249.949 339.105 258.013 1.00 43.50  ? 11   LEU A CG    1 
ATOM   49    C CD1   . LEU A 1 11   ? 250.735 338.230 257.052 1.00 43.50  ? 11   LEU A CD1   1 
ATOM   50    C CD2   . LEU A 1 11   ? 248.597 338.484 258.329 1.00 43.50  ? 11   LEU A CD2   1 
ATOM   51    N N     . ASP A 1 12   ? 251.642 340.419 262.172 1.00 45.80  ? 12   ASP A N     1 
ATOM   52    C CA    . ASP A 1 12   ? 251.845 340.214 263.602 1.00 45.80  ? 12   ASP A CA    1 
ATOM   53    C C     . ASP A 1 12   ? 251.031 341.209 264.420 1.00 45.80  ? 12   ASP A C     1 
ATOM   54    O O     . ASP A 1 12   ? 250.446 340.849 265.448 1.00 45.80  ? 12   ASP A O     1 
ATOM   55    C CB    . ASP A 1 12   ? 253.336 340.316 263.937 1.00 45.80  ? 12   ASP A CB    1 
ATOM   56    C CG    . ASP A 1 12   ? 253.604 340.387 265.432 1.00 45.80  ? 12   ASP A CG    1 
ATOM   57    O OD1   . ASP A 1 12   ? 253.412 341.466 266.032 1.00 45.80  ? 12   ASP A OD1   1 
ATOM   58    O OD2   . ASP A 1 12   ? 254.010 339.356 266.009 1.00 45.80  ? 12   ASP A OD2   1 
ATOM   59    N N     . GLY A 1 13   ? 250.986 342.469 263.981 1.00 42.64  ? 13   GLY A N     1 
ATOM   60    C CA    . GLY A 1 13   ? 250.169 343.453 264.674 1.00 42.64  ? 13   GLY A CA    1 
ATOM   61    C C     . GLY A 1 13   ? 248.690 343.119 264.629 1.00 42.64  ? 13   GLY A C     1 
ATOM   62    O O     . GLY A 1 13   ? 247.981 343.249 265.632 1.00 42.64  ? 13   GLY A O     1 
ATOM   63    N N     . TYR A 1 14   ? 248.204 342.681 263.465 1.00 35.02  ? 14   TYR A N     1 
ATOM   64    C CA    . TYR A 1 14   ? 246.806 342.275 263.352 1.00 35.02  ? 14   TYR A CA    1 
ATOM   65    C C     . TYR A 1 14   ? 246.509 341.071 264.239 1.00 35.02  ? 14   TYR A C     1 
ATOM   66    O O     . TYR A 1 14   ? 245.446 341.001 264.868 1.00 35.02  ? 14   TYR A O     1 
ATOM   67    C CB    . TYR A 1 14   ? 246.461 341.970 261.895 1.00 35.02  ? 14   TYR A CB    1 
ATOM   68    C CG    . TYR A 1 14   ? 245.987 343.174 261.111 1.00 35.02  ? 14   TYR A CG    1 
ATOM   69    C CD1   . TYR A 1 14   ? 244.705 343.680 261.287 1.00 35.02  ? 14   TYR A CD1   1 
ATOM   70    C CD2   . TYR A 1 14   ? 246.819 343.802 260.194 1.00 35.02  ? 14   TYR A CD2   1 
ATOM   71    C CE1   . TYR A 1 14   ? 244.267 344.779 260.572 1.00 35.02  ? 14   TYR A CE1   1 
ATOM   72    C CE2   . TYR A 1 14   ? 246.390 344.902 259.476 1.00 35.02  ? 14   TYR A CE2   1 
ATOM   73    C CZ    . TYR A 1 14   ? 245.114 345.386 259.668 1.00 35.02  ? 14   TYR A CZ    1 
ATOM   74    O OH    . TYR A 1 14   ? 244.684 346.481 258.955 1.00 35.02  ? 14   TYR A OH    1 
ATOM   75    N N     . ALA A 1 15   ? 247.435 340.111 264.296 1.00 34.87  ? 15   ALA A N     1 
ATOM   76    C CA    . ALA A 1 15   ? 247.250 338.950 265.160 1.00 34.87  ? 15   ALA A CA    1 
ATOM   77    C C     . ALA A 1 15   ? 247.216 339.354 266.627 1.00 34.87  ? 15   ALA A C     1 
ATOM   78    O O     . ALA A 1 15   ? 246.412 338.827 267.405 1.00 34.87  ? 15   ALA A O     1 
ATOM   79    C CB    . ALA A 1 15   ? 248.357 337.926 264.909 1.00 34.87  ? 15   ALA A CB    1 
ATOM   80    N N     . ARG A 1 16   ? 248.088 340.283 267.026 1.00 37.41  ? 16   ARG A N     1 
ATOM   81    C CA    . ARG A 1 16   ? 248.068 340.775 268.399 1.00 37.41  ? 16   ARG A CA    1 
ATOM   82    C C     . ARG A 1 16   ? 246.749 341.468 268.714 1.00 37.41  ? 16   ARG A C     1 
ATOM   83    O O     . ARG A 1 16   ? 246.176 341.269 269.792 1.00 37.41  ? 16   ARG A O     1 
ATOM   84    C CB    . ARG A 1 16   ? 249.241 341.727 268.635 1.00 37.41  ? 16   ARG A CB    1 
ATOM   85    C CG    . ARG A 1 16   ? 250.338 341.158 269.519 1.00 37.41  ? 16   ARG A CG    1 
ATOM   86    C CD    . ARG A 1 16   ? 251.076 342.265 270.258 1.00 37.41  ? 16   ARG A CD    1 
ATOM   87    N NE    . ARG A 1 16   ? 251.629 343.262 269.349 1.00 37.41  ? 16   ARG A NE    1 
ATOM   88    C CZ    . ARG A 1 16   ? 252.721 343.089 268.616 1.00 37.41  ? 16   ARG A CZ    1 
ATOM   89    N NH1   . ARG A 1 16   ? 253.415 341.963 268.665 1.00 37.41  ? 16   ARG A NH1   1 
ATOM   90    N NH2   . ARG A 1 16   ? 253.128 344.070 267.817 1.00 37.41  ? 16   ARG A NH2   1 
ATOM   91    N N     . LEU A 1 17   ? 246.252 342.284 267.781 1.00 28.81  ? 17   LEU A N     1 
ATOM   92    C CA    . LEU A 1 17   ? 244.968 342.951 267.980 1.00 28.81  ? 17   LEU A CA    1 
ATOM   93    C C     . LEU A 1 17   ? 243.842 341.936 268.136 1.00 28.81  ? 17   LEU A C     1 
ATOM   94    O O     . LEU A 1 17   ? 242.996 342.058 269.032 1.00 28.81  ? 17   LEU A O     1 
ATOM   95    C CB    . LEU A 1 17   ? 244.690 343.895 266.808 1.00 28.81  ? 17   LEU A CB    1 
ATOM   96    C CG    . LEU A 1 17   ? 243.251 344.366 266.580 1.00 28.81  ? 17   LEU A CG    1 
ATOM   97    C CD1   . LEU A 1 17   ? 242.740 345.169 267.764 1.00 28.81  ? 17   LEU A CD1   1 
ATOM   98    C CD2   . LEU A 1 17   ? 243.150 345.176 265.296 1.00 28.81  ? 17   LEU A CD2   1 
ATOM   99    N N     . VAL A 1 18   ? 243.823 340.917 267.274 1.00 32.07  ? 18   VAL A N     1 
ATOM   100   C CA    . VAL A 1 18   ? 242.779 339.898 267.342 1.00 32.07  ? 18   VAL A CA    1 
ATOM   101   C C     . VAL A 1 18   ? 242.852 339.146 268.665 1.00 32.07  ? 18   VAL A C     1 
ATOM   102   O O     . VAL A 1 18   ? 241.831 338.925 269.327 1.00 32.07  ? 18   VAL A O     1 
ATOM   103   C CB    . VAL A 1 18   ? 242.884 338.944 266.138 1.00 32.07  ? 18   VAL A CB    1 
ATOM   104   C CG1   . VAL A 1 18   ? 242.052 337.692 266.372 1.00 32.07  ? 18   VAL A CG1   1 
ATOM   105   C CG2   . VAL A 1 18   ? 242.446 339.649 264.864 1.00 32.07  ? 18   VAL A CG2   1 
ATOM   106   N N     . GLN A 1 19   ? 244.060 338.758 269.080 1.00 30.63  ? 19   GLN A N     1 
ATOM   107   C CA    . GLN A 1 19   ? 244.215 338.026 270.333 1.00 30.63  ? 19   GLN A CA    1 
ATOM   108   C C     . GLN A 1 19   ? 243.779 338.870 271.524 1.00 30.63  ? 19   GLN A C     1 
ATOM   109   O O     . GLN A 1 19   ? 243.121 338.367 272.443 1.00 30.63  ? 19   GLN A O     1 
ATOM   110   C CB    . GLN A 1 19   ? 245.666 337.572 270.496 1.00 30.63  ? 19   GLN A CB    1 
ATOM   111   C CG    . GLN A 1 19   ? 245.977 336.935 271.842 1.00 30.63  ? 19   GLN A CG    1 
ATOM   112   C CD    . GLN A 1 19   ? 245.026 335.806 272.186 1.00 30.63  ? 19   GLN A CD    1 
ATOM   113   O OE1   . GLN A 1 19   ? 244.319 335.859 273.193 1.00 30.63  ? 19   GLN A OE1   1 
ATOM   114   N NE2   . GLN A 1 19   ? 245.005 334.774 271.350 1.00 30.63  ? 19   GLN A NE2   1 
ATOM   115   N N     . GLN A 1 20   ? 244.128 340.158 271.526 1.00 34.95  ? 20   GLN A N     1 
ATOM   116   C CA    . GLN A 1 20   ? 243.779 341.025 272.642 1.00 34.95  ? 20   GLN A CA    1 
ATOM   117   C C     . GLN A 1 20   ? 242.308 341.417 272.657 1.00 34.95  ? 20   GLN A C     1 
ATOM   118   O O     . GLN A 1 20   ? 241.794 341.784 273.719 1.00 34.95  ? 20   GLN A O     1 
ATOM   119   C CB    . GLN A 1 20   ? 244.643 342.288 272.618 1.00 34.95  ? 20   GLN A CB    1 
ATOM   120   C CG    . GLN A 1 20   ? 246.098 342.052 272.986 1.00 34.95  ? 20   GLN A CG    1 
ATOM   121   C CD    . GLN A 1 20   ? 246.828 343.336 273.328 1.00 34.95  ? 20   GLN A CD    1 
ATOM   122   O OE1   . GLN A 1 20   ? 246.371 344.430 272.997 1.00 34.95  ? 20   GLN A OE1   1 
ATOM   123   N NE2   . GLN A 1 20   ? 247.968 343.208 273.996 1.00 34.95  ? 20   GLN A NE2   1 
ATOM   124   N N     . THR A 1 21   ? 241.617 341.350 271.520 1.00 34.75  ? 21   THR A N     1 
ATOM   125   C CA    . THR A 1 21   ? 240.224 341.781 271.461 1.00 34.75  ? 21   THR A CA    1 
ATOM   126   C C     . THR A 1 21   ? 239.218 340.641 271.479 1.00 34.75  ? 21   THR A C     1 
ATOM   127   O O     . THR A 1 21   ? 238.318 340.640 272.323 1.00 34.75  ? 21   THR A O     1 
ATOM   128   C CB    . THR A 1 21   ? 239.986 342.631 270.208 1.00 34.75  ? 21   THR A CB    1 
ATOM   129   O OG1   . THR A 1 21   ? 241.008 343.629 270.106 1.00 34.75  ? 21   THR A OG1   1 
ATOM   130   C CG2   . THR A 1 21   ? 238.630 343.310 270.286 1.00 34.75  ? 21   THR A CG2   1 
ATOM   131   N N     . ILE A 1 22   ? 239.335 339.667 270.578 1.00 28.23  ? 22   ILE A N     1 
ATOM   132   C CA    . ILE A 1 22   ? 238.305 338.646 270.421 1.00 28.23  ? 22   ILE A CA    1 
ATOM   133   C C     . ILE A 1 22   ? 238.764 337.331 271.038 1.00 28.23  ? 22   ILE A C     1 
ATOM   134   O O     . ILE A 1 22   ? 238.039 336.720 271.832 1.00 28.23  ? 22   ILE A O     1 
ATOM   135   C CB    . ILE A 1 22   ? 237.943 338.456 268.936 1.00 28.23  ? 22   ILE A CB    1 
ATOM   136   C CG1   . ILE A 1 22   ? 237.263 339.712 268.390 1.00 28.23  ? 22   ILE A CG1   1 
ATOM   137   C CG2   . ILE A 1 22   ? 237.048 337.240 268.755 1.00 28.23  ? 22   ILE A CG2   1 
ATOM   138   C CD1   . ILE A 1 22   ? 237.373 339.859 266.889 1.00 28.23  ? 22   ILE A CD1   1 
ATOM   139   N N     . LEU A 1 23   ? 239.973 336.890 270.684 1.00 29.34  ? 23   LEU A N     1 
ATOM   140   C CA    . LEU A 1 23   ? 240.466 335.591 271.127 1.00 29.34  ? 23   LEU A CA    1 
ATOM   141   C C     . LEU A 1 23   ? 240.712 335.523 272.629 1.00 29.34  ? 23   LEU A C     1 
ATOM   142   O O     . LEU A 1 23   ? 240.902 334.421 273.154 1.00 29.34  ? 23   LEU A O     1 
ATOM   143   C CB    . LEU A 1 23   ? 241.751 335.237 270.377 1.00 29.34  ? 23   LEU A CB    1 
ATOM   144   C CG    . LEU A 1 23   ? 241.574 334.378 269.122 1.00 29.34  ? 23   LEU A CG    1 
ATOM   145   C CD1   . LEU A 1 23   ? 242.858 334.338 268.308 1.00 29.34  ? 23   LEU A CD1   1 
ATOM   146   C CD2   . LEU A 1 23   ? 241.124 332.973 269.492 1.00 29.34  ? 23   LEU A CD2   1 
ATOM   147   N N     . CYS A 1 24   ? 240.721 336.661 273.327 1.00 34.63  ? 24   CYS A N     1 
ATOM   148   C CA    . CYS A 1 24   ? 240.897 336.649 274.774 1.00 34.63  ? 24   CYS A CA    1 
ATOM   149   C C     . CYS A 1 24   ? 239.752 335.941 275.488 1.00 34.63  ? 24   CYS A C     1 
ATOM   150   O O     . CYS A 1 24   ? 239.955 335.395 276.578 1.00 34.63  ? 24   CYS A O     1 
ATOM   151   C CB    . CYS A 1 24   ? 241.044 338.085 275.288 1.00 34.63  ? 24   CYS A CB    1 
ATOM   152   S SG    . CYS A 1 24   ? 240.596 338.348 277.021 1.00 34.63  ? 24   CYS A SG    1 
ATOM   153   N N     . HIS A 1 25   ? 238.564 335.913 274.887 1.00 34.05  ? 25   HIS A N     1 
ATOM   154   C CA    . HIS A 1 25   ? 237.383 335.287 275.471 1.00 34.05  ? 25   HIS A CA    1 
ATOM   155   C C     . HIS A 1 25   ? 237.024 333.995 274.742 1.00 34.05  ? 25   HIS A C     1 
ATOM   156   O O     . HIS A 1 25   ? 235.852 333.707 274.496 1.00 34.05  ? 25   HIS A O     1 
ATOM   157   C CB    . HIS A 1 25   ? 236.198 336.250 275.460 1.00 34.05  ? 25   HIS A CB    1 
ATOM   158   C CG    . HIS A 1 25   ? 236.574 337.676 275.716 1.00 34.05  ? 25   HIS A CG    1 
ATOM   159   N ND1   . HIS A 1 25   ? 237.060 338.111 276.930 1.00 34.05  ? 25   HIS A ND1   1 
ATOM   160   C CD2   . HIS A 1 25   ? 236.536 338.766 274.913 1.00 34.05  ? 25   HIS A CD2   1 
ATOM   161   C CE1   . HIS A 1 25   ? 237.303 339.408 276.864 1.00 34.05  ? 25   HIS A CE1   1 
ATOM   162   N NE2   . HIS A 1 25   ? 236.994 339.829 275.651 1.00 34.05  ? 25   HIS A NE2   1 
ATOM   163   N N     . GLN A 1 26   ? 238.043 333.206 274.386 1.00 33.47  ? 26   GLN A N     1 
ATOM   164   C CA    . GLN A 1 26   ? 237.816 331.990 273.612 1.00 33.47  ? 26   GLN A CA    1 
ATOM   165   C C     . GLN A 1 26   ? 236.927 330.998 274.354 1.00 33.47  ? 26   GLN A C     1 
ATOM   166   O O     . GLN A 1 26   ? 236.165 330.259 273.719 1.00 33.47  ? 26   GLN A O     1 
ATOM   167   C CB    . GLN A 1 26   ? 239.156 331.343 273.254 1.00 33.47  ? 26   GLN A CB    1 
ATOM   168   C CG    . GLN A 1 26   ? 239.047 330.038 272.476 1.00 33.47  ? 26   GLN A CG    1 
ATOM   169   C CD    . GLN A 1 26   ? 238.116 330.141 271.283 1.00 33.47  ? 26   GLN A CD    1 
ATOM   170   O OE1   . GLN A 1 26   ? 237.196 329.337 271.128 1.00 33.47  ? 26   GLN A OE1   1 
ATOM   171   N NE2   . GLN A 1 26   ? 238.354 331.130 270.428 1.00 33.47  ? 26   GLN A NE2   1 
ATOM   172   N N     . ASN A 1 27   ? 237.001 330.974 275.690 1.00 34.96  ? 27   ASN A N     1 
ATOM   173   C CA    . ASN A 1 27   ? 236.205 330.070 276.516 1.00 34.96  ? 27   ASN A CA    1 
ATOM   174   C C     . ASN A 1 27   ? 236.480 328.623 276.124 1.00 34.96  ? 27   ASN A C     1 
ATOM   175   O O     . ASN A 1 27   ? 235.649 327.992 275.458 1.00 34.96  ? 27   ASN A O     1 
ATOM   176   C CB    . ASN A 1 27   ? 234.712 330.390 276.400 1.00 34.96  ? 27   ASN A CB    1 
ATOM   177   C CG    . ASN A 1 27   ? 233.875 329.649 277.426 1.00 34.96  ? 27   ASN A CG    1 
ATOM   178   O OD1   . ASN A 1 27   ? 233.434 328.524 277.190 1.00 34.96  ? 27   ASN A OD1   1 
ATOM   179   N ND2   . ASN A 1 27   ? 233.651 330.279 278.573 1.00 34.96  ? 27   ASN A ND2   1 
ATOM   180   N N     . PRO A 1 28   ? 237.637 328.074 276.496 1.00 35.42  ? 28   PRO A N     1 
ATOM   181   C CA    . PRO A 1 28   ? 238.009 326.726 276.046 1.00 35.42  ? 28   PRO A CA    1 
ATOM   182   C C     . PRO A 1 28   ? 237.041 325.662 276.545 1.00 35.42  ? 28   PRO A C     1 
ATOM   183   O O     . PRO A 1 28   ? 236.071 325.936 277.257 1.00 35.42  ? 28   PRO A O     1 
ATOM   184   C CB    . PRO A 1 28   ? 239.410 326.525 276.635 1.00 35.42  ? 28   PRO A CB    1 
ATOM   185   C CG    . PRO A 1 28   ? 239.492 327.491 277.771 1.00 35.42  ? 28   PRO A CG    1 
ATOM   186   C CD    . PRO A 1 28   ? 238.659 328.670 277.373 1.00 35.42  ? 28   PRO A CD    1 
ATOM   187   N N     . VAL A 1 29   ? 237.322 324.422 276.129 1.00 39.33  ? 29   VAL A N     1 
ATOM   188   C CA    . VAL A 1 29   ? 236.505 323.232 276.375 1.00 39.33  ? 29   VAL A CA    1 
ATOM   189   C C     . VAL A 1 29   ? 235.276 323.271 275.476 1.00 39.33  ? 29   VAL A C     1 
ATOM   190   O O     . VAL A 1 29   ? 235.008 322.320 274.733 1.00 39.33  ? 29   VAL A O     1 
ATOM   191   C CB    . VAL A 1 29   ? 236.111 323.078 277.858 1.00 39.33  ? 29   VAL A CB    1 
ATOM   192   C CG1   . VAL A 1 29   ? 235.289 321.815 278.059 1.00 39.33  ? 29   VAL A CG1   1 
ATOM   193   C CG2   . VAL A 1 29   ? 237.353 323.053 278.740 1.00 39.33  ? 29   VAL A CG2   1 
ATOM   194   N N     . THR A 1 30   ? 234.520 324.366 275.534 1.00 37.56  ? 30   THR A N     1 
ATOM   195   C CA    . THR A 1 30   ? 233.362 324.561 274.669 1.00 37.56  ? 30   THR A CA    1 
ATOM   196   C C     . THR A 1 30   ? 233.688 325.371 273.420 1.00 37.56  ? 30   THR A C     1 
ATOM   197   O O     . THR A 1 30   ? 233.293 324.982 272.316 1.00 37.56  ? 30   THR A O     1 
ATOM   198   C CB    . THR A 1 30   ? 232.231 325.244 275.447 1.00 37.56  ? 30   THR A CB    1 
ATOM   199   O OG1   . THR A 1 30   ? 231.588 324.281 276.291 1.00 37.56  ? 30   THR A OG1   1 
ATOM   200   C CG2   . THR A 1 30   ? 231.201 325.844 274.500 1.00 37.56  ? 30   THR A CG2   1 
ATOM   201   N N     . GLY A 1 31   ? 234.418 326.473 273.563 1.00 40.85  ? 31   GLY A N     1 
ATOM   202   C CA    . GLY A 1 31   ? 234.807 327.285 272.430 1.00 40.85  ? 31   GLY A CA    1 
ATOM   203   C C     . GLY A 1 31   ? 233.820 328.352 272.015 1.00 40.85  ? 31   GLY A C     1 
ATOM   204   O O     . GLY A 1 31   ? 234.015 328.973 270.963 1.00 40.85  ? 31   GLY A O     1 
ATOM   205   N N     . LEU A 1 32   ? 232.772 328.590 272.798 1.00 64.40  ? 32   LEU A N     1 
ATOM   206   C CA    . LEU A 1 32   ? 231.779 329.613 272.494 1.00 64.40  ? 32   LEU A CA    1 
ATOM   207   C C     . LEU A 1 32   ? 232.055 330.843 273.350 1.00 64.40  ? 32   LEU A C     1 
ATOM   208   O O     . LEU A 1 32   ? 232.000 330.772 274.583 1.00 64.40  ? 32   LEU A O     1 
ATOM   209   C CB    . LEU A 1 32   ? 230.363 329.091 272.739 1.00 64.40  ? 32   LEU A CB    1 
ATOM   210   C CG    . LEU A 1 32   ? 229.626 328.513 271.529 1.00 64.40  ? 32   LEU A CG    1 
ATOM   211   C CD1   . LEU A 1 32   ? 230.281 327.224 271.055 1.00 64.40  ? 32   LEU A CD1   1 
ATOM   212   C CD2   . LEU A 1 32   ? 228.158 328.284 271.855 1.00 64.40  ? 32   LEU A CD2   1 
ATOM   213   N N     . LEU A 1 33   ? 232.348 331.967 272.696 1.00 64.40  ? 33   LEU A N     1 
ATOM   214   C CA    . LEU A 1 33   ? 232.653 333.196 273.410 1.00 64.40  ? 33   LEU A CA    1 
ATOM   215   C C     . LEU A 1 33   ? 231.381 333.825 273.974 1.00 64.40  ? 33   LEU A C     1 
ATOM   216   O O     . LEU A 1 33   ? 230.307 333.715 273.377 1.00 64.40  ? 33   LEU A O     1 
ATOM   217   C CB    . LEU A 1 33   ? 233.348 334.200 272.493 1.00 64.40  ? 33   LEU A CB    1 
ATOM   218   C CG    . LEU A 1 33   ? 234.445 333.735 271.531 1.00 64.40  ? 33   LEU A CG    1 
ATOM   219   C CD1   . LEU A 1 33   ? 233.858 333.264 270.212 1.00 64.40  ? 33   LEU A CD1   1 
ATOM   220   C CD2   . LEU A 1 33   ? 235.454 334.847 271.300 1.00 64.40  ? 33   LEU A CD2   1 
ATOM   221   N N     . PRO A 1 34   ? 231.477 334.487 275.125 1.00 64.40  ? 34   PRO A N     1 
ATOM   222   C CA    . PRO A 1 34   ? 230.338 335.265 275.620 1.00 64.40  ? 34   PRO A CA    1 
ATOM   223   C C     . PRO A 1 34   ? 230.071 336.466 274.728 1.00 64.40  ? 34   PRO A C     1 
ATOM   224   O O     . PRO A 1 34   ? 230.967 336.984 274.058 1.00 64.40  ? 34   PRO A O     1 
ATOM   225   C CB    . PRO A 1 34   ? 230.782 335.697 277.022 1.00 64.40  ? 34   PRO A CB    1 
ATOM   226   C CG    . PRO A 1 34   ? 232.272 335.673 276.970 1.00 64.40  ? 34   PRO A CG    1 
ATOM   227   C CD    . PRO A 1 34   ? 232.640 334.564 276.026 1.00 64.40  ? 34   PRO A CD    1 
ATOM   228   N N     . ALA A 1 35   ? 228.814 336.908 274.723 1.00 54.58  ? 35   ALA A N     1 
ATOM   229   C CA    . ALA A 1 35   ? 228.416 338.026 273.876 1.00 54.58  ? 35   ALA A CA    1 
ATOM   230   C C     . ALA A 1 35   ? 228.712 339.362 274.546 1.00 54.58  ? 35   ALA A C     1 
ATOM   231   O O     . ALA A 1 35   ? 227.820 340.208 274.670 1.00 54.58  ? 35   ALA A O     1 
ATOM   232   C CB    . ALA A 1 35   ? 226.931 337.928 273.525 1.00 54.58  ? 35   ALA A CB    1 
ATOM   233   N N     . SER A 1 36   ? 229.961 339.551 274.979 1.00 59.90  ? 36   SER A N     1 
ATOM   234   C CA    . SER A 1 36   ? 230.435 340.790 275.591 1.00 59.90  ? 36   SER A CA    1 
ATOM   235   C C     . SER A 1 36   ? 229.702 341.117 276.889 1.00 59.90  ? 36   SER A C     1 
ATOM   236   O O     . SER A 1 36   ? 228.717 340.460 277.242 1.00 59.90  ? 36   SER A O     1 
ATOM   237   C CB    . SER A 1 36   ? 230.309 341.958 274.607 1.00 59.90  ? 36   SER A CB    1 
ATOM   238   O OG    . SER A 1 36   ? 230.974 341.672 273.389 1.00 59.90  ? 36   SER A OG    1 
ATOM   239   N N     . TYR A 1 37   ? 230.198 342.125 277.611 1.00 63.15  ? 37   TYR A N     1 
ATOM   240   C CA    . TYR A 1 37   ? 229.596 342.594 278.856 1.00 63.15  ? 37   TYR A CA    1 
ATOM   241   C C     . TYR A 1 37   ? 229.454 341.475 279.881 1.00 63.15  ? 37   TYR A C     1 
ATOM   242   O O     . TYR A 1 37   ? 230.087 340.422 279.757 1.00 63.15  ? 37   TYR A O     1 
ATOM   243   C CB    . TYR A 1 37   ? 228.232 343.234 278.581 1.00 63.15  ? 37   TYR A CB    1 
ATOM   244   N N     . ASP A 1 38   ? 228.634 341.702 280.906 1.00 63.64  ? 38   ASP A N     1 
ATOM   245   C CA    . ASP A 1 38   ? 228.371 340.691 281.930 1.00 63.64  ? 38   ASP A CA    1 
ATOM   246   C C     . ASP A 1 38   ? 227.090 339.921 281.604 1.00 63.64  ? 38   ASP A C     1 
ATOM   247   O O     . ASP A 1 38   ? 226.137 339.869 282.381 1.00 63.64  ? 38   ASP A O     1 
ATOM   248   C CB    . ASP A 1 38   ? 228.298 341.343 283.306 1.00 63.64  ? 38   ASP A CB    1 
ATOM   249   C CG    . ASP A 1 38   ? 227.508 342.638 283.299 1.00 63.64  ? 38   ASP A CG    1 
ATOM   250   O OD1   . ASP A 1 38   ? 226.661 342.819 282.399 1.00 63.64  ? 38   ASP A OD1   1 
ATOM   251   O OD2   . ASP A 1 38   ? 227.736 343.478 284.195 1.00 63.64  ? 38   ASP A OD2   1 
ATOM   252   N N     . GLN A 1 39   ? 227.085 339.313 280.419 1.00 58.46  ? 39   GLN A N     1 
ATOM   253   C CA    . GLN A 1 39   ? 225.945 338.541 279.941 1.00 58.46  ? 39   GLN A CA    1 
ATOM   254   C C     . GLN A 1 39   ? 226.093 337.046 280.183 1.00 58.46  ? 39   GLN A C     1 
ATOM   255   O O     . GLN A 1 39   ? 225.118 336.388 280.559 1.00 58.46  ? 39   GLN A O     1 
ATOM   256   C CB    . GLN A 1 39   ? 225.726 338.792 278.444 1.00 58.46  ? 39   GLN A CB    1 
ATOM   257   C CG    . GLN A 1 39   ? 225.528 340.255 278.075 1.00 58.46  ? 39   GLN A CG    1 
ATOM   258   C CD    . GLN A 1 39   ? 224.142 340.769 278.422 1.00 58.46  ? 39   GLN A CD    1 
ATOM   259   O OE1   . GLN A 1 39   ? 223.302 340.032 278.938 1.00 58.46  ? 39   GLN A OE1   1 
ATOM   260   N NE2   . GLN A 1 39   ? 223.897 342.043 278.137 1.00 58.46  ? 39   GLN A NE2   1 
ATOM   261   N N     . LYS A 1 40   ? 227.293 336.499 279.975 1.00 51.26  ? 40   LYS A N     1 
ATOM   262   C CA    . LYS A 1 40   ? 227.566 335.071 280.150 1.00 51.26  ? 40   LYS A CA    1 
ATOM   263   C C     . LYS A 1 40   ? 226.645 334.208 279.290 1.00 51.26  ? 40   LYS A C     1 
ATOM   264   O O     . LYS A 1 40   ? 226.256 333.108 279.688 1.00 51.26  ? 40   LYS A O     1 
ATOM   265   C CB    . LYS A 1 40   ? 227.467 334.659 281.623 1.00 51.26  ? 40   LYS A CB    1 
ATOM   266   C CG    . LYS A 1 40   ? 228.187 335.595 282.582 1.00 51.26  ? 40   LYS A CG    1 
ATOM   267   C CD    . LYS A 1 40   ? 229.655 335.744 282.213 1.00 51.26  ? 40   LYS A CD    1 
ATOM   268   C CE    . LYS A 1 40   ? 230.506 336.035 283.438 1.00 51.26  ? 40   LYS A CE    1 
ATOM   269   N NZ    . LYS A 1 40   ? 229.882 337.062 284.317 1.00 51.26  ? 40   LYS A NZ    1 
ATOM   270   N N     . ASP A 1 41   ? 226.291 334.705 278.107 1.00 43.63  ? 41   ASP A N     1 
ATOM   271   C CA    . ASP A 1 41   ? 225.448 333.985 277.165 1.00 43.63  ? 41   ASP A CA    1 
ATOM   272   C C     . ASP A 1 41   ? 226.068 334.057 275.778 1.00 43.63  ? 41   ASP A C     1 
ATOM   273   O O     . ASP A 1 41   ? 226.717 335.044 275.421 1.00 43.63  ? 41   ASP A O     1 
ATOM   274   C CB    . ASP A 1 41   ? 224.021 334.555 277.134 1.00 43.63  ? 41   ASP A CB    1 
ATOM   275   C CG    . ASP A 1 41   ? 223.188 334.107 278.319 1.00 43.63  ? 41   ASP A CG    1 
ATOM   276   O OD1   . ASP A 1 41   ? 223.568 333.116 278.976 1.00 43.63  ? 41   ASP A OD1   1 
ATOM   277   O OD2   . ASP A 1 41   ? 222.154 334.750 278.597 1.00 43.63  ? 41   ASP A OD2   1 
ATOM   278   N N     . ALA A 1 42   ? 225.864 333.000 274.998 1.00 33.62  ? 42   ALA A N     1 
ATOM   279   C CA    . ALA A 1 42   ? 226.447 332.876 273.669 1.00 33.62  ? 42   ALA A CA    1 
ATOM   280   C C     . ALA A 1 42   ? 225.354 332.948 272.612 1.00 33.62  ? 42   ALA A C     1 
ATOM   281   O O     . ALA A 1 42   ? 224.349 332.234 272.701 1.00 33.62  ? 42   ALA A O     1 
ATOM   282   C CB    . ALA A 1 42   ? 227.227 331.566 273.535 1.00 33.62  ? 42   ALA A CB    1 
ATOM   283   N N     . TRP A 1 43   ? 225.555 333.808 271.619 1.00 37.02  ? 43   TRP A N     1 
ATOM   284   C CA    . TRP A 1 43   ? 224.657 333.921 270.477 1.00 37.02  ? 43   TRP A CA    1 
ATOM   285   C C     . TRP A 1 43   ? 225.304 333.263 269.267 1.00 37.02  ? 43   TRP A C     1 
ATOM   286   O O     . TRP A 1 43   ? 226.494 333.470 269.006 1.00 37.02  ? 43   TRP A O     1 
ATOM   287   C CB    . TRP A 1 43   ? 224.332 335.385 270.173 1.00 37.02  ? 43   TRP A CB    1 
ATOM   288   C CG    . TRP A 1 43   ? 223.075 335.883 270.823 1.00 37.02  ? 43   TRP A CG    1 
ATOM   289   C CD1   . TRP A 1 43   ? 221.850 336.021 270.237 1.00 37.02  ? 43   TRP A CD1   1 
ATOM   290   C CD2   . TRP A 1 43   ? 222.922 336.322 272.178 1.00 37.02  ? 43   TRP A CD2   1 
ATOM   291   N NE1   . TRP A 1 43   ? 220.943 336.513 271.144 1.00 37.02  ? 43   TRP A NE1   1 
ATOM   292   C CE2   . TRP A 1 43   ? 221.576 336.707 272.343 1.00 37.02  ? 43   TRP A CE2   1 
ATOM   293   C CE3   . TRP A 1 43   ? 223.791 336.425 273.268 1.00 37.02  ? 43   TRP A CE3   1 
ATOM   294   C CZ2   . TRP A 1 43   ? 221.080 337.186 273.554 1.00 37.02  ? 43   TRP A CZ2   1 
ATOM   295   C CZ3   . TRP A 1 43   ? 223.296 336.901 274.469 1.00 37.02  ? 43   TRP A CZ3   1 
ATOM   296   C CH2   . TRP A 1 43   ? 221.954 337.276 274.602 1.00 37.02  ? 43   TRP A CH2   1 
ATOM   297   N N     . VAL A 1 44   ? 224.522 332.465 268.538 1.00 35.81  ? 44   VAL A N     1 
ATOM   298   C CA    . VAL A 1 44   ? 225.052 331.766 267.369 1.00 35.81  ? 44   VAL A CA    1 
ATOM   299   C C     . VAL A 1 44   ? 225.503 332.766 266.311 1.00 35.81  ? 44   VAL A C     1 
ATOM   300   O O     . VAL A 1 44   ? 226.617 332.678 265.779 1.00 35.81  ? 44   VAL A O     1 
ATOM   301   C CB    . VAL A 1 44   ? 224.004 330.788 266.809 1.00 35.81  ? 44   VAL A CB    1 
ATOM   302   C CG1   . VAL A 1 44   ? 224.564 330.037 265.611 1.00 35.81  ? 44   VAL A CG1   1 
ATOM   303   C CG2   . VAL A 1 44   ? 223.546 329.822 267.891 1.00 35.81  ? 44   VAL A CG2   1 
ATOM   304   N N     . ARG A 1 45   ? 224.644 333.739 265.997 1.00 42.43  ? 45   ARG A N     1 
ATOM   305   C CA    . ARG A 1 45   ? 224.978 334.729 264.978 1.00 42.43  ? 45   ARG A CA    1 
ATOM   306   C C     . ARG A 1 45   ? 226.178 335.571 265.393 1.00 42.43  ? 45   ARG A C     1 
ATOM   307   O O     . ARG A 1 45   ? 227.066 335.845 264.577 1.00 42.43  ? 45   ARG A O     1 
ATOM   308   C CB    . ARG A 1 45   ? 223.765 335.617 264.699 1.00 42.43  ? 45   ARG A CB    1 
ATOM   309   C CG    . ARG A 1 45   ? 224.006 336.700 263.661 1.00 42.43  ? 45   ARG A CG    1 
ATOM   310   C CD    . ARG A 1 45   ? 222.713 337.404 263.260 1.00 42.43  ? 45   ARG A CD    1 
ATOM   311   N NE    . ARG A 1 45   ? 222.064 338.072 264.382 1.00 42.43  ? 45   ARG A NE    1 
ATOM   312   C CZ    . ARG A 1 45   ? 221.036 337.578 265.059 1.00 42.43  ? 45   ARG A CZ    1 
ATOM   313   N NH1   . ARG A 1 45   ? 220.505 336.406 264.752 1.00 42.43  ? 45   ARG A NH1   1 
ATOM   314   N NH2   . ARG A 1 45   ? 220.527 338.279 266.068 1.00 42.43  ? 45   ARG A NH2   1 
ATOM   315   N N     . ASP A 1 46   ? 226.221 335.990 266.661 1.00 35.64  ? 46   ASP A N     1 
ATOM   316   C CA    . ASP A 1 46   ? 227.326 336.818 267.133 1.00 35.64  ? 46   ASP A CA    1 
ATOM   317   C C     . ASP A 1 46   ? 228.651 336.070 267.048 1.00 35.64  ? 46   ASP A C     1 
ATOM   318   O O     . ASP A 1 46   ? 229.653 336.613 266.573 1.00 35.64  ? 46   ASP A O     1 
ATOM   319   C CB    . ASP A 1 46   ? 227.058 337.281 268.565 1.00 35.64  ? 46   ASP A CB    1 
ATOM   320   C CG    . ASP A 1 46   ? 225.995 338.359 268.641 1.00 35.64  ? 46   ASP A CG    1 
ATOM   321   O OD1   . ASP A 1 46   ? 225.142 338.420 267.730 1.00 35.64  ? 46   ASP A OD1   1 
ATOM   322   O OD2   . ASP A 1 46   ? 226.012 339.146 269.610 1.00 35.64  ? 46   ASP A OD2   1 
ATOM   323   N N     . ASN A 1 47   ? 228.670 334.811 267.495 1.00 39.25  ? 47   ASN A N     1 
ATOM   324   C CA    . ASN A 1 47   ? 229.898 334.023 267.434 1.00 39.25  ? 47   ASN A CA    1 
ATOM   325   C C     . ASN A 1 47   ? 230.317 333.757 265.993 1.00 39.25  ? 47   ASN A C     1 
ATOM   326   O O     . ASN A 1 47   ? 231.510 333.816 265.664 1.00 39.25  ? 47   ASN A O     1 
ATOM   327   C CB    . ASN A 1 47   ? 229.714 332.707 268.191 1.00 39.25  ? 47   ASN A CB    1 
ATOM   328   C CG    . ASN A 1 47   ? 229.666 332.900 269.695 1.00 39.25  ? 47   ASN A CG    1 
ATOM   329   O OD1   . ASN A 1 47   ? 230.611 332.559 270.406 1.00 39.25  ? 47   ASN A OD1   1 
ATOM   330   N ND2   . ASN A 1 47   ? 228.561 333.448 270.186 1.00 39.25  ? 47   ASN A ND2   1 
ATOM   331   N N     . VAL A 1 48   ? 229.349 333.458 265.121 1.00 36.90  ? 48   VAL A N     1 
ATOM   332   C CA    . VAL A 1 48   ? 229.661 333.203 263.718 1.00 36.90  ? 48   VAL A CA    1 
ATOM   333   C C     . VAL A 1 48   ? 230.273 334.440 263.074 1.00 36.90  ? 48   VAL A C     1 
ATOM   334   O O     . VAL A 1 48   ? 231.264 334.350 262.338 1.00 36.90  ? 48   VAL A O     1 
ATOM   335   C CB    . VAL A 1 48   ? 228.400 332.733 262.968 1.00 36.90  ? 48   VAL A CB    1 
ATOM   336   C CG1   . VAL A 1 48   ? 228.566 332.917 261.470 1.00 36.90  ? 48   VAL A CG1   1 
ATOM   337   C CG2   . VAL A 1 48   ? 228.104 331.277 263.294 1.00 36.90  ? 48   VAL A CG2   1 
ATOM   338   N N     . TYR A 1 49   ? 229.702 335.616 263.343 1.00 32.38  ? 49   TYR A N     1 
ATOM   339   C CA    . TYR A 1 49   ? 230.240 336.841 262.762 1.00 32.38  ? 49   TYR A CA    1 
ATOM   340   C C     . TYR A 1 49   ? 231.582 337.212 263.385 1.00 32.38  ? 49   TYR A C     1 
ATOM   341   O O     . TYR A 1 49   ? 232.433 337.817 262.722 1.00 32.38  ? 49   TYR A O     1 
ATOM   342   C CB    . TYR A 1 49   ? 229.235 337.980 262.920 1.00 32.38  ? 49   TYR A CB    1 
ATOM   343   C CG    . TYR A 1 49   ? 228.252 338.084 261.776 1.00 32.38  ? 49   TYR A CG    1 
ATOM   344   C CD1   . TYR A 1 49   ? 228.675 338.438 260.501 1.00 32.38  ? 49   TYR A CD1   1 
ATOM   345   C CD2   . TYR A 1 49   ? 226.902 337.822 261.969 1.00 32.38  ? 49   TYR A CD2   1 
ATOM   346   C CE1   . TYR A 1 49   ? 227.780 338.533 259.452 1.00 32.38  ? 49   TYR A CE1   1 
ATOM   347   C CE2   . TYR A 1 49   ? 226.000 337.914 260.925 1.00 32.38  ? 49   TYR A CE2   1 
ATOM   348   C CZ    . TYR A 1 49   ? 226.444 338.269 259.670 1.00 32.38  ? 49   TYR A CZ    1 
ATOM   349   O OH    . TYR A 1 49   ? 225.549 338.362 258.629 1.00 32.38  ? 49   TYR A OH    1 
ATOM   350   N N     . SER A 1 50   ? 231.789 336.866 264.658 1.00 37.71  ? 50   SER A N     1 
ATOM   351   C CA    . SER A 1 50   ? 233.054 337.183 265.313 1.00 37.71  ? 50   SER A CA    1 
ATOM   352   C C     . SER A 1 50   ? 234.190 336.318 264.781 1.00 37.71  ? 50   SER A C     1 
ATOM   353   O O     . SER A 1 50   ? 235.318 336.799 264.619 1.00 37.71  ? 50   SER A O     1 
ATOM   354   C CB    . SER A 1 50   ? 232.916 337.016 266.826 1.00 37.71  ? 50   SER A CB    1 
ATOM   355   O OG    . SER A 1 50   ? 231.795 337.731 267.318 1.00 37.71  ? 50   SER A OG    1 
ATOM   356   N N     . ILE A 1 51   ? 233.917 335.040 264.506 1.00 28.51  ? 51   ILE A N     1 
ATOM   357   C CA    . ILE A 1 51   ? 234.962 334.139 264.030 1.00 28.51  ? 51   ILE A CA    1 
ATOM   358   C C     . ILE A 1 51   ? 235.403 334.442 262.604 1.00 28.51  ? 51   ILE A C     1 
ATOM   359   O O     . ILE A 1 51   ? 236.380 333.849 262.129 1.00 28.51  ? 51   ILE A O     1 
ATOM   360   C CB    . ILE A 1 51   ? 234.497 332.671 264.145 1.00 28.51  ? 51   ILE A CB    1 
ATOM   361   C CG1   . ILE A 1 51   ? 235.701 331.734 264.278 1.00 28.51  ? 51   ILE A CG1   1 
ATOM   362   C CG2   . ILE A 1 51   ? 233.647 332.280 262.947 1.00 28.51  ? 51   ILE A CG2   1 
ATOM   363   C CD1   . ILE A 1 51   ? 236.593 332.043 265.460 1.00 28.51  ? 51   ILE A CD1   1 
ATOM   364   N N     . LEU A 1 52   ? 234.713 335.351 261.910 1.00 35.47  ? 52   LEU A N     1 
ATOM   365   C CA    . LEU A 1 52   ? 235.103 335.694 260.545 1.00 35.47  ? 52   LEU A CA    1 
ATOM   366   C C     . LEU A 1 52   ? 236.487 336.329 260.505 1.00 35.47  ? 52   LEU A C     1 
ATOM   367   O O     . LEU A 1 52   ? 237.290 336.029 259.613 1.00 35.47  ? 52   LEU A O     1 
ATOM   368   C CB    . LEU A 1 52   ? 234.067 336.630 259.923 1.00 35.47  ? 52   LEU A CB    1 
ATOM   369   C CG    . LEU A 1 52   ? 232.627 336.118 259.906 1.00 35.47  ? 52   LEU A CG    1 
ATOM   370   C CD1   . LEU A 1 52   ? 231.737 337.048 259.096 1.00 35.47  ? 52   LEU A CD1   1 
ATOM   371   C CD2   . LEU A 1 52   ? 232.574 334.700 259.360 1.00 35.47  ? 52   LEU A CD2   1 
ATOM   372   N N     . ALA A 1 53   ? 236.781 337.218 261.457 1.00 24.55  ? 53   ALA A N     1 
ATOM   373   C CA    . ALA A 1 53   ? 238.099 337.843 261.502 1.00 24.55  ? 53   ALA A CA    1 
ATOM   374   C C     . ALA A 1 53   ? 239.191 336.810 261.748 1.00 24.55  ? 53   ALA A C     1 
ATOM   375   O O     . ALA A 1 53   ? 240.255 336.860 261.121 1.00 24.55  ? 53   ALA A O     1 
ATOM   376   C CB    . ALA A 1 53   ? 238.132 338.926 262.580 1.00 24.55  ? 53   ALA A CB    1 
ATOM   377   N N     . VAL A 1 54   ? 238.942 335.863 262.656 1.00 30.48  ? 54   VAL A N     1 
ATOM   378   C CA    . VAL A 1 54   ? 239.923 334.818 262.934 1.00 30.48  ? 54   VAL A CA    1 
ATOM   379   C C     . VAL A 1 54   ? 240.138 333.946 261.703 1.00 30.48  ? 54   VAL A C     1 
ATOM   380   O O     . VAL A 1 54   ? 241.273 333.581 261.373 1.00 30.48  ? 54   VAL A O     1 
ATOM   381   C CB    . VAL A 1 54   ? 239.482 333.984 264.152 1.00 30.48  ? 54   VAL A CB    1 
ATOM   382   C CG1   . VAL A 1 54   ? 240.401 332.788 264.345 1.00 30.48  ? 54   VAL A CG1   1 
ATOM   383   C CG2   . VAL A 1 54   ? 239.452 334.849 265.403 1.00 30.48  ? 54   VAL A CG2   1 
ATOM   384   N N     . TRP A 1 55   ? 239.053 333.595 261.007 1.00 28.15  ? 55   TRP A N     1 
ATOM   385   C CA    . TRP A 1 55   ? 239.177 332.784 259.800 1.00 28.15  ? 55   TRP A CA    1 
ATOM   386   C C     . TRP A 1 55   ? 239.968 333.513 258.720 1.00 28.15  ? 55   TRP A C     1 
ATOM   387   O O     . TRP A 1 55   ? 240.829 332.917 258.060 1.00 28.15  ? 55   TRP A O     1 
ATOM   388   C CB    . TRP A 1 55   ? 237.790 332.399 259.286 1.00 28.15  ? 55   TRP A CB    1 
ATOM   389   C CG    . TRP A 1 55   ? 237.814 331.587 258.027 1.00 28.15  ? 55   TRP A CG    1 
ATOM   390   C CD1   . TRP A 1 55   ? 238.696 330.596 257.706 1.00 28.15  ? 55   TRP A CD1   1 
ATOM   391   C CD2   . TRP A 1 55   ? 236.911 331.695 256.920 1.00 28.15  ? 55   TRP A CD2   1 
ATOM   392   N NE1   . TRP A 1 55   ? 238.399 330.082 256.467 1.00 28.15  ? 55   TRP A NE1   1 
ATOM   393   C CE2   . TRP A 1 55   ? 237.308 330.739 255.963 1.00 28.15  ? 55   TRP A CE2   1 
ATOM   394   C CE3   . TRP A 1 55   ? 235.807 332.507 256.644 1.00 28.15  ? 55   TRP A CE3   1 
ATOM   395   C CZ2   . TRP A 1 55   ? 236.640 330.574 254.752 1.00 28.15  ? 55   TRP A CZ2   1 
ATOM   396   C CZ3   . TRP A 1 55   ? 235.145 332.341 255.441 1.00 28.15  ? 55   TRP A CZ3   1 
ATOM   397   C CH2   . TRP A 1 55   ? 235.564 331.382 254.510 1.00 28.15  ? 55   TRP A CH2   1 
ATOM   398   N N     . GLY A 1 56   ? 239.693 334.805 258.527 1.00 30.39  ? 56   GLY A N     1 
ATOM   399   C CA    . GLY A 1 56   ? 240.445 335.571 257.546 1.00 30.39  ? 56   GLY A CA    1 
ATOM   400   C C     . GLY A 1 56   ? 241.911 335.703 257.911 1.00 30.39  ? 56   GLY A C     1 
ATOM   401   O O     . GLY A 1 56   ? 242.787 335.622 257.046 1.00 30.39  ? 56   GLY A O     1 
ATOM   402   N N     . LEU A 1 57   ? 242.198 335.905 259.200 1.00 27.06  ? 57   LEU A N     1 
ATOM   403   C CA    . LEU A 1 57   ? 243.582 335.981 259.651 1.00 27.06  ? 57   LEU A CA    1 
ATOM   404   C C     . LEU A 1 57   ? 244.308 334.662 259.418 1.00 27.06  ? 57   LEU A C     1 
ATOM   405   O O     . LEU A 1 57   ? 245.467 334.648 258.986 1.00 27.06  ? 57   LEU A O     1 
ATOM   406   C CB    . LEU A 1 57   ? 243.623 336.365 261.129 1.00 27.06  ? 57   LEU A CB    1 
ATOM   407   C CG    . LEU A 1 57   ? 244.994 336.610 261.756 1.00 27.06  ? 57   LEU A CG    1 
ATOM   408   C CD1   . LEU A 1 57   ? 245.842 337.498 260.858 1.00 27.06  ? 57   LEU A CD1   1 
ATOM   409   C CD2   . LEU A 1 57   ? 244.834 337.224 263.133 1.00 27.06  ? 57   LEU A CD2   1 
ATOM   410   N N     . GLY A 1 58   ? 243.642 333.541 259.704 1.00 29.34  ? 58   GLY A N     1 
ATOM   411   C CA    . GLY A 1 58   ? 244.245 332.245 259.439 1.00 29.34  ? 58   GLY A CA    1 
ATOM   412   C C     . GLY A 1 58   ? 244.495 332.011 257.962 1.00 29.34  ? 58   GLY A C     1 
ATOM   413   O O     . GLY A 1 58   ? 245.537 331.474 257.576 1.00 29.34  ? 58   GLY A O     1 
ATOM   414   N N     . LEU A 1 59   ? 243.543 332.411 257.115 1.00 29.28  ? 59   LEU A N     1 
ATOM   415   C CA    . LEU A 1 59   ? 243.736 332.281 255.674 1.00 29.28  ? 59   LEU A CA    1 
ATOM   416   C C     . LEU A 1 59   ? 244.911 333.127 255.198 1.00 29.28  ? 59   LEU A C     1 
ATOM   417   O O     . LEU A 1 59   ? 245.693 332.693 254.345 1.00 29.28  ? 59   LEU A O     1 
ATOM   418   C CB    . LEU A 1 59   ? 242.456 332.671 254.935 1.00 29.28  ? 59   LEU A CB    1 
ATOM   419   C CG    . LEU A 1 59   ? 241.459 331.541 254.674 1.00 29.28  ? 59   LEU A CG    1 
ATOM   420   C CD1   . LEU A 1 59   ? 240.127 332.098 254.195 1.00 29.28  ? 59   LEU A CD1   1 
ATOM   421   C CD2   . LEU A 1 59   ? 242.022 330.549 253.667 1.00 29.28  ? 59   LEU A CD2   1 
ATOM   422   N N     . ALA A 1 60   ? 245.046 334.343 255.735 1.00 27.76  ? 60   ALA A N     1 
ATOM   423   C CA    . ALA A 1 60   ? 246.177 335.191 255.372 1.00 27.76  ? 60   ALA A CA    1 
ATOM   424   C C     . ALA A 1 60   ? 247.497 334.582 255.829 1.00 27.76  ? 60   ALA A C     1 
ATOM   425   O O     . ALA A 1 60   ? 248.493 334.620 255.096 1.00 27.76  ? 60   ALA A O     1 
ATOM   426   C CB    . ALA A 1 60   ? 245.997 336.588 255.966 1.00 27.76  ? 60   ALA A CB    1 
ATOM   427   N N     . TYR A 1 61   ? 247.526 334.019 257.039 1.00 30.98  ? 61   TYR A N     1 
ATOM   428   C CA    . TYR A 1 61   ? 248.762 333.435 257.555 1.00 30.98  ? 61   TYR A CA    1 
ATOM   429   C C     . TYR A 1 61   ? 249.141 332.167 256.801 1.00 30.98  ? 61   TYR A C     1 
ATOM   430   O O     . TYR A 1 61   ? 250.330 331.847 256.675 1.00 30.98  ? 61   TYR A O     1 
ATOM   431   C CB    . TYR A 1 61   ? 248.625 333.146 259.050 1.00 30.98  ? 61   TYR A CB    1 
ATOM   432   C CG    . TYR A 1 61   ? 249.229 334.208 259.941 1.00 30.98  ? 61   TYR A CG    1 
ATOM   433   C CD1   . TYR A 1 61   ? 250.605 334.391 259.999 1.00 30.98  ? 61   TYR A CD1   1 
ATOM   434   C CD2   . TYR A 1 61   ? 248.427 335.021 260.728 1.00 30.98  ? 61   TYR A CD2   1 
ATOM   435   C CE1   . TYR A 1 61   ? 251.164 335.359 260.813 1.00 30.98  ? 61   TYR A CE1   1 
ATOM   436   C CE2   . TYR A 1 61   ? 248.976 335.992 261.546 1.00 30.98  ? 61   TYR A CE2   1 
ATOM   437   C CZ    . TYR A 1 61   ? 250.345 336.156 261.584 1.00 30.98  ? 61   TYR A CZ    1 
ATOM   438   O OH    . TYR A 1 61   ? 250.896 337.120 262.396 1.00 30.98  ? 61   TYR A OH    1 
ATOM   439   N N     . ARG A 1 62   ? 248.148 331.425 256.302 1.00 30.62  ? 62   ARG A N     1 
ATOM   440   C CA    . ARG A 1 62   ? 248.436 330.171 255.613 1.00 30.62  ? 62   ARG A CA    1 
ATOM   441   C C     . ARG A 1 62   ? 249.250 330.396 254.343 1.00 30.62  ? 62   ARG A C     1 
ATOM   442   O O     . ARG A 1 62   ? 250.046 329.532 253.956 1.00 30.62  ? 62   ARG A O     1 
ATOM   443   C CB    . ARG A 1 62   ? 247.128 329.442 255.295 1.00 30.62  ? 62   ARG A CB    1 
ATOM   444   C CG    . ARG A 1 62   ? 247.291 328.158 254.495 1.00 30.62  ? 62   ARG A CG    1 
ATOM   445   C CD    . ARG A 1 62   ? 248.205 327.173 255.209 1.00 30.62  ? 62   ARG A CD    1 
ATOM   446   N NE    . ARG A 1 62   ? 247.627 326.695 256.460 1.00 30.62  ? 62   ARG A NE    1 
ATOM   447   C CZ    . ARG A 1 62   ? 248.240 325.873 257.301 1.00 30.62  ? 62   ARG A CZ    1 
ATOM   448   N NH1   . ARG A 1 62   ? 249.456 325.414 257.057 1.00 30.62  ? 62   ARG A NH1   1 
ATOM   449   N NH2   . ARG A 1 62   ? 247.615 325.501 258.415 1.00 30.62  ? 62   ARG A NH2   1 
ATOM   450   N N     . LYS A 1 63   ? 249.075 331.547 253.689 1.00 33.58  ? 63   LYS A N     1 
ATOM   451   C CA    . LYS A 1 63   ? 249.806 331.817 252.454 1.00 33.58  ? 63   LYS A CA    1 
ATOM   452   C C     . LYS A 1 63   ? 251.310 331.866 252.696 1.00 33.58  ? 63   LYS A C     1 
ATOM   453   O O     . LYS A 1 63   ? 252.092 331.341 251.894 1.00 33.58  ? 63   LYS A O     1 
ATOM   454   C CB    . LYS A 1 63   ? 249.319 333.125 251.831 1.00 33.58  ? 63   LYS A CB    1 
ATOM   455   C CG    . LYS A 1 63   ? 247.929 333.044 251.225 1.00 33.58  ? 63   LYS A CG    1 
ATOM   456   C CD    . LYS A 1 63   ? 247.211 334.380 251.312 1.00 33.58  ? 63   LYS A CD    1 
ATOM   457   C CE    . LYS A 1 63   ? 247.909 335.437 250.473 1.00 33.58  ? 63   LYS A CE    1 
ATOM   458   N NZ    . LYS A 1 63   ? 246.962 336.482 249.997 1.00 33.58  ? 63   LYS A NZ    1 
ATOM   459   N N     . ASN A 1 64   ? 251.735 332.492 253.794 1.00 41.08  ? 64   ASN A N     1 
ATOM   460   C CA    . ASN A 1 64   ? 253.155 332.583 254.136 1.00 41.08  ? 64   ASN A CA    1 
ATOM   461   C C     . ASN A 1 64   ? 253.584 331.299 254.849 1.00 41.08  ? 64   ASN A C     1 
ATOM   462   O O     . ASN A 1 64   ? 253.770 331.243 256.066 1.00 41.08  ? 64   ASN A O     1 
ATOM   463   C CB    . ASN A 1 64   ? 253.423 333.818 254.986 1.00 41.08  ? 64   ASN A CB    1 
ATOM   464   C CG    . ASN A 1 64   ? 252.849 335.080 254.375 1.00 41.08  ? 64   ASN A CG    1 
ATOM   465   O OD1   . ASN A 1 64   ? 252.803 335.228 253.154 1.00 41.08  ? 64   ASN A OD1   1 
ATOM   466   N ND2   . ASN A 1 64   ? 252.407 336.000 255.224 1.00 41.08  ? 64   ASN A ND2   1 
ATOM   467   N N     . ALA A 1 65   ? 253.742 330.249 254.051 1.00 48.24  ? 65   ALA A N     1 
ATOM   468   C CA    . ALA A 1 65   ? 254.111 328.933 254.551 1.00 48.24  ? 65   ALA A CA    1 
ATOM   469   C C     . ALA A 1 65   ? 255.637 328.814 254.586 1.00 48.24  ? 65   ALA A C     1 
ATOM   470   O O     . ALA A 1 65   ? 256.351 329.815 254.486 1.00 48.24  ? 65   ALA A O     1 
ATOM   471   C CB    . ALA A 1 65   ? 253.452 327.848 253.693 1.00 48.24  ? 65   ALA A CB    1 
ATOM   472   N N     . ASP A 1 66   ? 256.143 327.591 254.758 1.00 60.48  ? 66   ASP A N     1 
ATOM   473   C CA    . ASP A 1 66   ? 257.563 327.223 254.764 1.00 60.48  ? 66   ASP A CA    1 
ATOM   474   C C     . ASP A 1 66   ? 258.287 327.694 256.018 1.00 60.48  ? 66   ASP A C     1 
ATOM   475   O O     . ASP A 1 66   ? 259.528 327.676 256.044 1.00 60.48  ? 66   ASP A O     1 
ATOM   476   C CB    . ASP A 1 66   ? 258.310 327.743 253.530 1.00 60.48  ? 66   ASP A CB    1 
ATOM   477   C CG    . ASP A 1 66   ? 259.416 326.808 253.081 1.00 60.48  ? 66   ASP A CG    1 
ATOM   478   O OD1   . ASP A 1 66   ? 259.113 325.644 252.745 1.00 60.48  ? 66   ASP A OD1   1 
ATOM   479   O OD2   . ASP A 1 66   ? 260.589 327.238 253.064 1.00 60.48  ? 66   ASP A OD2   1 
ATOM   480   N N     . ARG A 1 67   ? 257.568 328.112 257.058 1.00 60.94  ? 67   ARG A N     1 
ATOM   481   C CA    . ARG A 1 67   ? 258.174 328.461 258.334 1.00 60.94  ? 67   ARG A CA    1 
ATOM   482   C C     . ARG A 1 67   ? 257.389 327.804 259.459 1.00 60.94  ? 67   ARG A C     1 
ATOM   483   O O     . ARG A 1 67   ? 256.162 327.687 259.386 1.00 60.94  ? 67   ARG A O     1 
ATOM   484   C CB    . ARG A 1 67   ? 258.224 329.979 258.543 1.00 60.94  ? 67   ARG A CB    1 
ATOM   485   C CG    . ARG A 1 67   ? 259.539 330.468 259.132 1.00 60.94  ? 67   ARG A CG    1 
ATOM   486   C CD    . ARG A 1 67   ? 259.673 331.979 259.034 1.00 60.94  ? 67   ARG A CD    1 
ATOM   487   N NE    . ARG A 1 67   ? 259.031 332.659 260.153 1.00 60.94  ? 67   ARG A NE    1 
ATOM   488   C CZ    . ARG A 1 67   ? 259.540 332.738 261.375 1.00 60.94  ? 67   ARG A CZ    1 
ATOM   489   N NH1   . ARG A 1 67   ? 260.708 332.193 261.675 1.00 60.94  ? 67   ARG A NH1   1 
ATOM   490   N NH2   . ARG A 1 67   ? 258.861 333.382 262.320 1.00 60.94  ? 67   ARG A NH2   1 
ATOM   491   N N     . ASP A 1 68   ? 258.107 327.371 260.499 1.00 55.08  ? 68   ASP A N     1 
ATOM   492   C CA    . ASP A 1 68   ? 257.464 326.666 261.603 1.00 55.08  ? 68   ASP A CA    1 
ATOM   493   C C     . ASP A 1 68   ? 256.505 327.573 262.367 1.00 55.08  ? 68   ASP A C     1 
ATOM   494   O O     . ASP A 1 68   ? 255.397 327.156 262.721 1.00 55.08  ? 68   ASP A O     1 
ATOM   495   C CB    . ASP A 1 68   ? 258.522 326.091 262.545 1.00 55.08  ? 68   ASP A CB    1 
ATOM   496   C CG    . ASP A 1 68   ? 259.091 324.776 262.049 1.00 55.08  ? 68   ASP A CG    1 
ATOM   497   O OD1   . ASP A 1 68   ? 258.299 323.902 261.639 1.00 55.08  ? 68   ASP A OD1   1 
ATOM   498   O OD2   . ASP A 1 68   ? 260.329 324.617 262.068 1.00 55.08  ? 68   ASP A OD2   1 
ATOM   499   N N     . GLU A 1 69   ? 256.914 328.816 262.633 1.00 54.20  ? 69   GLU A N     1 
ATOM   500   C CA    . GLU A 1 69   ? 256.088 329.714 263.436 1.00 54.20  ? 69   GLU A CA    1 
ATOM   501   C C     . GLU A 1 69   ? 254.801 330.083 262.708 1.00 54.20  ? 69   GLU A C     1 
ATOM   502   O O     . GLU A 1 69   ? 253.712 330.061 263.296 1.00 54.20  ? 69   GLU A O     1 
ATOM   503   C CB    . GLU A 1 69   ? 256.884 330.968 263.799 1.00 54.20  ? 69   GLU A CB    1 
ATOM   504   C CG    . GLU A 1 69   ? 257.990 330.734 264.818 1.00 54.20  ? 69   GLU A CG    1 
ATOM   505   C CD    . GLU A 1 69   ? 259.301 330.313 264.179 1.00 54.20  ? 69   GLU A CD    1 
ATOM   506   O OE1   . GLU A 1 69   ? 259.278 329.807 263.037 1.00 54.20  ? 69   GLU A OE1   1 
ATOM   507   O OE2   . GLU A 1 69   ? 260.358 330.489 264.821 1.00 54.20  ? 69   GLU A OE2   1 
ATOM   508   N N     . ASP A 1 70   ? 254.907 330.433 261.423 1.00 52.92  ? 70   ASP A N     1 
ATOM   509   C CA    . ASP A 1 70   ? 253.719 330.791 260.654 1.00 52.92  ? 70   ASP A CA    1 
ATOM   510   C C     . ASP A 1 70   ? 252.780 329.601 260.508 1.00 52.92  ? 70   ASP A C     1 
ATOM   511   O O     . ASP A 1 70   ? 251.556 329.748 260.619 1.00 52.92  ? 70   ASP A O     1 
ATOM   512   C CB    . ASP A 1 70   ? 254.126 331.328 259.282 1.00 52.92  ? 70   ASP A CB    1 
ATOM   513   C CG    . ASP A 1 70   ? 255.058 332.519 259.376 1.00 52.92  ? 70   ASP A CG    1 
ATOM   514   O OD1   . ASP A 1 70   ? 255.358 332.954 260.508 1.00 52.92  ? 70   ASP A OD1   1 
ATOM   515   O OD2   . ASP A 1 70   ? 255.492 333.021 258.318 1.00 52.92  ? 70   ASP A OD2   1 
ATOM   516   N N     . LYS A 1 71   ? 253.337 328.414 260.256 1.00 43.58  ? 71   LYS A N     1 
ATOM   517   C CA    . LYS A 1 71   ? 252.513 327.213 260.165 1.00 43.58  ? 71   LYS A CA    1 
ATOM   518   C C     . LYS A 1 71   ? 251.800 326.936 261.482 1.00 43.58  ? 71   LYS A C     1 
ATOM   519   O O     . LYS A 1 71   ? 250.615 326.588 261.492 1.00 43.58  ? 71   LYS A O     1 
ATOM   520   C CB    . LYS A 1 71   ? 253.372 326.015 259.760 1.00 43.58  ? 71   LYS A CB    1 
ATOM   521   C CG    . LYS A 1 71   ? 253.441 325.773 258.261 1.00 43.58  ? 71   LYS A CG    1 
ATOM   522   C CD    . LYS A 1 71   ? 254.413 324.651 257.931 1.00 43.58  ? 71   LYS A CD    1 
ATOM   523   C CE    . LYS A 1 71   ? 254.021 323.939 256.647 1.00 43.58  ? 71   LYS A CE    1 
ATOM   524   N NZ    . LYS A 1 71   ? 252.851 323.040 256.846 1.00 43.58  ? 71   LYS A NZ    1 
ATOM   525   N N     . ALA A 1 72   ? 252.508 327.088 262.604 1.00 36.35  ? 72   ALA A N     1 
ATOM   526   C CA    . ALA A 1 72   ? 251.891 326.865 263.907 1.00 36.35  ? 72   ALA A CA    1 
ATOM   527   C C     . ALA A 1 72   ? 250.773 327.865 264.170 1.00 36.35  ? 72   ALA A C     1 
ATOM   528   O O     . ALA A 1 72   ? 249.707 327.494 264.673 1.00 36.35  ? 72   ALA A O     1 
ATOM   529   C CB    . ALA A 1 72   ? 252.948 326.939 265.008 1.00 36.35  ? 72   ALA A CB    1 
ATOM   530   N N     . LYS A 1 73   ? 250.997 329.139 263.838 1.00 36.06  ? 73   LYS A N     1 
ATOM   531   C CA    . LYS A 1 73   ? 249.964 330.151 264.048 1.00 36.06  ? 73   LYS A CA    1 
ATOM   532   C C     . LYS A 1 73   ? 248.734 329.868 263.192 1.00 36.06  ? 73   LYS A C     1 
ATOM   533   O O     . LYS A 1 73   ? 247.594 329.955 263.669 1.00 36.06  ? 73   LYS A O     1 
ATOM   534   C CB    . LYS A 1 73   ? 250.523 331.542 263.746 1.00 36.06  ? 73   LYS A CB    1 
ATOM   535   C CG    . LYS A 1 73   ? 251.564 332.026 264.743 1.00 36.06  ? 73   LYS A CG    1 
ATOM   536   C CD    . LYS A 1 73   ? 252.524 333.014 264.102 1.00 36.06  ? 73   LYS A CD    1 
ATOM   537   C CE    . LYS A 1 73   ? 253.646 333.393 265.055 1.00 36.06  ? 73   LYS A CE    1 
ATOM   538   N NZ    . LYS A 1 73   ? 253.125 333.976 266.322 1.00 36.06  ? 73   LYS A NZ    1 
ATOM   539   N N     . ALA A 1 74   ? 248.947 329.524 261.918 1.00 31.92  ? 74   ALA A N     1 
ATOM   540   C CA    . ALA A 1 74   ? 247.824 329.212 261.042 1.00 31.92  ? 74   ALA A CA    1 
ATOM   541   C C     . ALA A 1 74   ? 247.066 327.987 261.536 1.00 31.92  ? 74   ALA A C     1 
ATOM   542   O O     . ALA A 1 74   ? 245.828 327.971 261.536 1.00 31.92  ? 74   ALA A O     1 
ATOM   543   C CB    . ALA A 1 74   ? 248.317 328.999 259.610 1.00 31.92  ? 74   ALA A CB    1 
ATOM   544   N N     . TYR A 1 75   ? 247.792 326.951 261.964 1.00 33.60  ? 75   TYR A N     1 
ATOM   545   C CA    . TYR A 1 75   ? 247.144 325.753 262.482 1.00 33.60  ? 75   TYR A CA    1 
ATOM   546   C C     . TYR A 1 75   ? 246.341 326.063 263.736 1.00 33.60  ? 75   TYR A C     1 
ATOM   547   O O     . TYR A 1 75   ? 245.233 325.549 263.911 1.00 33.60  ? 75   TYR A O     1 
ATOM   548   C CB    . TYR A 1 75   ? 248.188 324.672 262.763 1.00 33.60  ? 75   TYR A CB    1 
ATOM   549   C CG    . TYR A 1 75   ? 247.628 323.431 263.422 1.00 33.60  ? 75   TYR A CG    1 
ATOM   550   C CD1   . TYR A 1 75   ? 246.863 322.524 262.700 1.00 33.60  ? 75   TYR A CD1   1 
ATOM   551   C CD2   . TYR A 1 75   ? 247.866 323.166 264.764 1.00 33.60  ? 75   TYR A CD2   1 
ATOM   552   C CE1   . TYR A 1 75   ? 246.350 321.388 263.297 1.00 33.60  ? 75   TYR A CE1   1 
ATOM   553   C CE2   . TYR A 1 75   ? 247.357 322.032 265.369 1.00 33.60  ? 75   TYR A CE2   1 
ATOM   554   C CZ    . TYR A 1 75   ? 246.600 321.147 264.631 1.00 33.60  ? 75   TYR A CZ    1 
ATOM   555   O OH    . TYR A 1 75   ? 246.091 320.018 265.230 1.00 33.60  ? 75   TYR A OH    1 
ATOM   556   N N     . GLU A 1 76   ? 246.882 326.905 264.620 1.00 31.50  ? 76   GLU A N     1 
ATOM   557   C CA    . GLU A 1 76   ? 246.152 327.288 265.824 1.00 31.50  ? 76   GLU A CA    1 
ATOM   558   C C     . GLU A 1 76   ? 244.874 328.043 265.479 1.00 31.50  ? 76   GLU A C     1 
ATOM   559   O O     . GLU A 1 76   ? 243.819 327.799 266.078 1.00 31.50  ? 76   GLU A O     1 
ATOM   560   C CB    . GLU A 1 76   ? 247.048 328.131 266.732 1.00 31.50  ? 76   GLU A CB    1 
ATOM   561   C CG    . GLU A 1 76   ? 246.297 328.951 267.769 1.00 31.50  ? 76   GLU A CG    1 
ATOM   562   C CD    . GLU A 1 76   ? 247.208 329.873 268.555 1.00 31.50  ? 76   GLU A CD    1 
ATOM   563   O OE1   . GLU A 1 76   ? 248.429 329.867 268.294 1.00 31.50  ? 76   GLU A OE1   1 
ATOM   564   O OE2   . GLU A 1 76   ? 246.703 330.603 269.433 1.00 31.50  ? 76   GLU A OE2   1 
ATOM   565   N N     . LEU A 1 77   ? 244.946 328.964 264.515 1.00 33.24  ? 77   LEU A N     1 
ATOM   566   C CA    . LEU A 1 77   ? 243.756 329.719 264.129 1.00 33.24  ? 77   LEU A CA    1 
ATOM   567   C C     . LEU A 1 77   ? 242.692 328.804 263.526 1.00 33.24  ? 77   LEU A C     1 
ATOM   568   O O     . LEU A 1 77   ? 241.504 328.898 263.869 1.00 33.24  ? 77   LEU A O     1 
ATOM   569   C CB    . LEU A 1 77   ? 244.139 330.832 263.152 1.00 33.24  ? 77   LEU A CB    1 
ATOM   570   C CG    . LEU A 1 77   ? 244.998 331.951 263.747 1.00 33.24  ? 77   LEU A CG    1 
ATOM   571   C CD1   . LEU A 1 77   ? 245.824 332.640 262.672 1.00 33.24  ? 77   LEU A CD1   1 
ATOM   572   C CD2   . LEU A 1 77   ? 244.131 332.959 264.487 1.00 33.24  ? 77   LEU A CD2   1 
ATOM   573   N N     . GLU A 1 78   ? 243.103 327.903 262.628 1.00 34.88  ? 78   GLU A N     1 
ATOM   574   C CA    . GLU A 1 78   ? 242.146 326.966 262.044 1.00 34.88  ? 78   GLU A CA    1 
ATOM   575   C C     . GLU A 1 78   ? 241.562 326.038 263.101 1.00 34.88  ? 78   GLU A C     1 
ATOM   576   O O     . GLU A 1 78   ? 240.373 325.705 263.053 1.00 34.88  ? 78   GLU A O     1 
ATOM   577   C CB    . GLU A 1 78   ? 242.795 326.161 260.917 1.00 34.88  ? 78   GLU A CB    1 
ATOM   578   C CG    . GLU A 1 78   ? 243.479 327.004 259.854 1.00 34.88  ? 78   GLU A CG    1 
ATOM   579   C CD    . GLU A 1 78   ? 243.960 326.180 258.676 1.00 34.88  ? 78   GLU A CD    1 
ATOM   580   O OE1   . GLU A 1 78   ? 244.454 325.055 258.897 1.00 34.88  ? 78   GLU A OE1   1 
ATOM   581   O OE2   . GLU A 1 78   ? 243.843 326.658 257.527 1.00 34.88  ? 78   GLU A OE2   1 
ATOM   582   N N     . GLN A 1 79   ? 242.380 325.604 264.063 1.00 38.78  ? 79   GLN A N     1 
ATOM   583   C CA    . GLN A 1 79   ? 241.878 324.750 265.133 1.00 38.78  ? 79   GLN A CA    1 
ATOM   584   C C     . GLN A 1 79   ? 240.867 325.488 266.000 1.00 38.78  ? 79   GLN A C     1 
ATOM   585   O O     . GLN A 1 79   ? 239.866 324.904 266.424 1.00 38.78  ? 79   GLN A O     1 
ATOM   586   C CB    . GLN A 1 79   ? 243.036 324.229 265.982 1.00 38.78  ? 79   GLN A CB    1 
ATOM   587   C CG    . GLN A 1 79   ? 243.794 323.074 265.349 1.00 38.78  ? 79   GLN A CG    1 
ATOM   588   C CD    . GLN A 1 79   ? 242.893 321.902 265.014 1.00 38.78  ? 79   GLN A CD    1 
ATOM   589   O OE1   . GLN A 1 79   ? 242.266 321.315 265.895 1.00 38.78  ? 79   GLN A OE1   1 
ATOM   590   N NE2   . GLN A 1 79   ? 242.825 321.555 263.734 1.00 38.78  ? 79   GLN A NE2   1 
ATOM   591   N N     . SER A 1 80   ? 241.114 326.769 266.281 1.00 30.65  ? 80   SER A N     1 
ATOM   592   C CA    . SER A 1 80   ? 240.145 327.554 267.041 1.00 30.65  ? 80   SER A CA    1 
ATOM   593   C C     . SER A 1 80   ? 238.830 327.691 266.281 1.00 30.65  ? 80   SER A C     1 
ATOM   594   O O     . SER A 1 80   ? 237.745 327.558 266.865 1.00 30.65  ? 80   SER A O     1 
ATOM   595   C CB    . SER A 1 80   ? 240.723 328.932 267.365 1.00 30.65  ? 80   SER A CB    1 
ATOM   596   O OG    . SER A 1 80   ? 241.865 328.824 268.197 1.00 30.65  ? 80   SER A OG    1 
ATOM   597   N N     . VAL A 1 81   ? 238.909 327.950 264.973 1.00 30.04  ? 81   VAL A N     1 
ATOM   598   C CA    . VAL A 1 81   ? 237.695 328.065 264.165 1.00 30.04  ? 81   VAL A CA    1 
ATOM   599   C C     . VAL A 1 81   ? 236.930 326.745 264.164 1.00 30.04  ? 81   VAL A C     1 
ATOM   600   O O     . VAL A 1 81   ? 235.701 326.713 264.316 1.00 30.04  ? 81   VAL A O     1 
ATOM   601   C CB    . VAL A 1 81   ? 238.044 328.518 262.736 1.00 30.04  ? 81   VAL A CB    1 
ATOM   602   C CG1   . VAL A 1 81   ? 236.815 328.463 261.847 1.00 30.04  ? 81   VAL A CG1   1 
ATOM   603   C CG2   . VAL A 1 81   ? 238.628 329.922 262.753 1.00 30.04  ? 81   VAL A CG2   1 
ATOM   604   N N     . VAL A 1 82   ? 237.652 325.634 263.998 1.00 30.73  ? 82   VAL A N     1 
ATOM   605   C CA    . VAL A 1 82   ? 237.020 324.318 263.981 1.00 30.73  ? 82   VAL A CA    1 
ATOM   606   C C     . VAL A 1 82   ? 236.396 324.006 265.336 1.00 30.73  ? 82   VAL A C     1 
ATOM   607   O O     . VAL A 1 82   ? 235.312 323.419 265.414 1.00 30.73  ? 82   VAL A O     1 
ATOM   608   C CB    . VAL A 1 82   ? 238.040 323.243 263.560 1.00 30.73  ? 82   VAL A CB    1 
ATOM   609   C CG1   . VAL A 1 82   ? 237.517 321.847 263.868 1.00 30.73  ? 82   VAL A CG1   1 
ATOM   610   C CG2   . VAL A 1 82   ? 238.365 323.374 262.079 1.00 30.73  ? 82   VAL A CG2   1 
ATOM   611   N N     . LYS A 1 83   ? 237.070 324.388 266.423 1.00 32.42  ? 83   LYS A N     1 
ATOM   612   C CA    . LYS A 1 83   ? 236.522 324.167 267.756 1.00 32.42  ? 83   LYS A CA    1 
ATOM   613   C C     . LYS A 1 83   ? 235.230 324.947 267.956 1.00 32.42  ? 83   LYS A C     1 
ATOM   614   O O     . LYS A 1 83   ? 234.259 324.420 268.513 1.00 32.42  ? 83   LYS A O     1 
ATOM   615   C CB    . LYS A 1 83   ? 237.553 324.557 268.816 1.00 32.42  ? 83   LYS A CB    1 
ATOM   616   C CG    . LYS A 1 83   ? 237.183 324.140 270.229 1.00 32.42  ? 83   LYS A CG    1 
ATOM   617   C CD    . LYS A 1 83   ? 237.971 324.934 271.258 1.00 32.42  ? 83   LYS A CD    1 
ATOM   618   C CE    . LYS A 1 83   ? 238.070 324.187 272.577 1.00 32.42  ? 83   LYS A CE    1 
ATOM   619   N NZ    . LYS A 1 83   ? 239.292 324.567 273.338 1.00 32.42  ? 83   LYS A NZ    1 
ATOM   620   N N     . LEU A 1 84   ? 235.199 326.205 267.509 1.00 30.04  ? 84   LEU A N     1 
ATOM   621   C CA    . LEU A 1 84   ? 233.967 326.983 267.599 1.00 30.04  ? 84   LEU A CA    1 
ATOM   622   C C     . LEU A 1 84   ? 232.851 326.338 266.784 1.00 30.04  ? 84   LEU A C     1 
ATOM   623   O O     . LEU A 1 84   ? 231.703 326.246 267.244 1.00 30.04  ? 84   LEU A O     1 
ATOM   624   C CB    . LEU A 1 84   ? 234.217 328.417 267.130 1.00 30.04  ? 84   LEU A CB    1 
ATOM   625   C CG    . LEU A 1 84   ? 233.264 329.510 267.623 1.00 30.04  ? 84   LEU A CG    1 
ATOM   626   C CD1   . LEU A 1 84   ? 233.964 330.851 267.598 1.00 30.04  ? 84   LEU A CD1   1 
ATOM   627   C CD2   . LEU A 1 84   ? 231.995 329.568 266.788 1.00 30.04  ? 84   LEU A CD2   1 
ATOM   628   N N     . MET A 1 85   ? 233.172 325.884 265.569 1.00 27.16  ? 85   MET A N     1 
ATOM   629   C CA    . MET A 1 85   ? 232.160 325.254 264.727 1.00 27.16  ? 85   MET A CA    1 
ATOM   630   C C     . MET A 1 85   ? 231.630 323.973 265.361 1.00 27.16  ? 85   MET A C     1 
ATOM   631   O O     . MET A 1 85   ? 230.422 323.713 265.332 1.00 27.16  ? 85   MET A O     1 
ATOM   632   C CB    . MET A 1 85   ? 232.733 324.973 263.338 1.00 27.16  ? 85   MET A CB    1 
ATOM   633   C CG    . MET A 1 85   ? 232.759 326.190 262.427 1.00 27.16  ? 85   MET A CG    1 
ATOM   634   S SD    . MET A 1 85   ? 231.223 327.134 262.490 1.00 27.16  ? 85   MET A SD    1 
ATOM   635   C CE    . MET A 1 85   ? 231.713 328.641 261.655 1.00 27.16  ? 85   MET A CE    1 
ATOM   636   N N     . ARG A 1 86   ? 232.517 323.162 265.944 1.00 34.99  ? 86   ARG A N     1 
ATOM   637   C CA    . ARG A 1 86   ? 232.083 321.929 266.594 1.00 34.99  ? 86   ARG A CA    1 
ATOM   638   C C     . ARG A 1 86   ? 231.246 322.218 267.833 1.00 34.99  ? 86   ARG A C     1 
ATOM   639   O O     . ARG A 1 86   ? 230.278 321.501 268.111 1.00 34.99  ? 86   ARG A O     1 
ATOM   640   C CB    . ARG A 1 86   ? 233.290 321.061 266.953 1.00 34.99  ? 86   ARG A CB    1 
ATOM   641   C CG    . ARG A 1 86   ? 234.100 320.574 265.758 1.00 34.99  ? 86   ARG A CG    1 
ATOM   642   C CD    . ARG A 1 86   ? 233.203 320.122 264.610 1.00 34.99  ? 86   ARG A CD    1 
ATOM   643   N NE    . ARG A 1 86   ? 232.238 319.104 265.014 1.00 34.99  ? 86   ARG A NE    1 
ATOM   644   C CZ    . ARG A 1 86   ? 232.548 317.863 265.363 1.00 34.99  ? 86   ARG A CZ    1 
ATOM   645   N NH1   . ARG A 1 86   ? 233.798 317.430 265.346 1.00 34.99  ? 86   ARG A NH1   1 
ATOM   646   N NH2   . ARG A 1 86   ? 231.578 317.032 265.733 1.00 34.99  ? 86   ARG A NH2   1 
ATOM   647   N N     . GLY A 1 87   ? 231.602 323.255 268.593 1.00 32.24  ? 87   GLY A N     1 
ATOM   648   C CA    . GLY A 1 87   ? 230.783 323.627 269.735 1.00 32.24  ? 87   GLY A CA    1 
ATOM   649   C C     . GLY A 1 87   ? 229.386 324.050 269.325 1.00 32.24  ? 87   GLY A C     1 
ATOM   650   O O     . GLY A 1 87   ? 228.391 323.634 269.928 1.00 32.24  ? 87   GLY A O     1 
ATOM   651   N N     . LEU A 1 88   ? 229.292 324.872 268.276 1.00 32.92  ? 88   LEU A N     1 
ATOM   652   C CA    . LEU A 1 88   ? 227.980 325.275 267.777 1.00 32.92  ? 88   LEU A CA    1 
ATOM   653   C C     . LEU A 1 88   ? 227.196 324.075 267.256 1.00 32.92  ? 88   LEU A C     1 
ATOM   654   O O     . LEU A 1 88   ? 225.983 323.966 267.485 1.00 32.92  ? 88   LEU A O     1 
ATOM   655   C CB    . LEU A 1 88   ? 228.135 326.333 266.686 1.00 32.92  ? 88   LEU A CB    1 
ATOM   656   C CG    . LEU A 1 88   ? 228.176 327.785 267.166 1.00 32.92  ? 88   LEU A CG    1 
ATOM   657   C CD1   . LEU A 1 88   ? 228.510 328.720 266.014 1.00 32.92  ? 88   LEU A CD1   1 
ATOM   658   C CD2   . LEU A 1 88   ? 226.862 328.177 267.822 1.00 32.92  ? 88   LEU A CD2   1 
ATOM   659   N N     . LEU A 1 89   ? 227.873 323.165 266.551 1.00 31.44  ? 89   LEU A N     1 
ATOM   660   C CA    . LEU A 1 89   ? 227.207 321.977 266.030 1.00 31.44  ? 89   LEU A CA    1 
ATOM   661   C C     . LEU A 1 89   ? 226.674 321.105 267.158 1.00 31.44  ? 89   LEU A C     1 
ATOM   662   O O     . LEU A 1 89   ? 225.559 320.583 267.072 1.00 31.44  ? 89   LEU A O     1 
ATOM   663   C CB    . LEU A 1 89   ? 228.168 321.185 265.144 1.00 31.44  ? 89   LEU A CB    1 
ATOM   664   C CG    . LEU A 1 89   ? 227.633 319.893 264.525 1.00 31.44  ? 89   LEU A CG    1 
ATOM   665   C CD1   . LEU A 1 89   ? 226.340 320.153 263.768 1.00 31.44  ? 89   LEU A CD1   1 
ATOM   666   C CD2   . LEU A 1 89   ? 228.676 319.264 263.614 1.00 31.44  ? 89   LEU A CD2   1 
ATOM   667   N N     . HIS A 1 90   ? 227.458 320.934 268.226 1.00 33.42  ? 90   HIS A N     1 
ATOM   668   C CA    . HIS A 1 90   ? 226.989 320.169 269.377 1.00 33.42  ? 90   HIS A CA    1 
ATOM   669   C C     . HIS A 1 90   ? 225.806 320.856 270.048 1.00 33.42  ? 90   HIS A C     1 
ATOM   670   O O     . HIS A 1 90   ? 224.855 320.193 270.484 1.00 33.42  ? 90   HIS A O     1 
ATOM   671   C CB    . HIS A 1 90   ? 228.131 319.967 270.372 1.00 33.42  ? 90   HIS A CB    1 
ATOM   672   C CG    . HIS A 1 90   ? 229.166 318.987 269.915 1.00 33.42  ? 90   HIS A CG    1 
ATOM   673   N ND1   . HIS A 1 90   ? 228.940 318.087 268.896 1.00 33.42  ? 90   HIS A ND1   1 
ATOM   674   C CD2   . HIS A 1 90   ? 230.434 318.766 270.337 1.00 33.42  ? 90   HIS A CD2   1 
ATOM   675   C CE1   . HIS A 1 90   ? 230.024 317.354 268.710 1.00 33.42  ? 90   HIS A CE1   1 
ATOM   676   N NE2   . HIS A 1 90   ? 230.944 317.745 269.572 1.00 33.42  ? 90   HIS A NE2   1 
ATOM   677   N N     . CYS A 1 91   ? 225.849 322.189 270.143 1.00 33.90  ? 91   CYS A N     1 
ATOM   678   C CA    . CYS A 1 91   ? 224.729 322.921 270.726 1.00 33.90  ? 91   CYS A CA    1 
ATOM   679   C C     . CYS A 1 91   ? 223.451 322.703 269.924 1.00 33.90  ? 91   CYS A C     1 
ATOM   680   O O     . CYS A 1 91   ? 222.372 322.516 270.500 1.00 33.90  ? 91   CYS A O     1 
ATOM   681   C CB    . CYS A 1 91   ? 225.063 324.410 270.814 1.00 33.90  ? 91   CYS A CB    1 
ATOM   682   S SG    . CYS A 1 91   ? 226.285 324.823 272.081 1.00 33.90  ? 91   CYS A SG    1 
ATOM   683   N N     . MET A 1 92   ? 223.549 322.727 268.592 1.00 31.70  ? 92   MET A N     1 
ATOM   684   C CA    . MET A 1 92   ? 222.379 322.424 267.768 1.00 31.70  ? 92   MET A CA    1 
ATOM   685   C C     . MET A 1 92   ? 221.950 320.967 267.917 1.00 31.70  ? 92   MET A C     1 
ATOM   686   O O     . MET A 1 92   ? 220.750 320.670 267.946 1.00 31.70  ? 92   MET A O     1 
ATOM   687   C CB    . MET A 1 92   ? 222.650 322.754 266.300 1.00 31.70  ? 92   MET A CB    1 
ATOM   688   C CG    . MET A 1 92   ? 223.238 324.131 266.058 1.00 31.70  ? 92   MET A CG    1 
ATOM   689   S SD    . MET A 1 92   ? 221.958 325.396 265.962 1.00 31.70  ? 92   MET A SD    1 
ATOM   690   C CE    . MET A 1 92   ? 222.851 326.727 265.164 1.00 31.70  ? 92   MET A CE    1 
ATOM   691   N N     . ILE A 1 93   ? 222.914 320.047 268.007 1.00 32.24  ? 93   ILE A N     1 
ATOM   692   C CA    . ILE A 1 93   ? 222.601 318.627 268.148 1.00 32.24  ? 93   ILE A CA    1 
ATOM   693   C C     . ILE A 1 93   ? 221.842 318.368 269.442 1.00 32.24  ? 93   ILE A C     1 
ATOM   694   O O     . ILE A 1 93   ? 220.998 317.466 269.509 1.00 32.24  ? 93   ILE A O     1 
ATOM   695   C CB    . ILE A 1 93   ? 223.897 317.795 268.061 1.00 32.24  ? 93   ILE A CB    1 
ATOM   696   C CG1   . ILE A 1 93   ? 224.360 317.678 266.608 1.00 32.24  ? 93   ILE A CG1   1 
ATOM   697   C CG2   . ILE A 1 93   ? 223.714 316.408 268.663 1.00 32.24  ? 93   ILE A CG2   1 
ATOM   698   C CD1   . ILE A 1 93   ? 225.799 317.237 266.460 1.00 32.24  ? 93   ILE A CD1   1 
ATOM   699   N N     . ARG A 1 94   ? 222.100 319.166 270.479 1.00 29.25  ? 94   ARG A N     1 
ATOM   700   C CA    . ARG A 1 94   ? 221.404 318.969 271.746 1.00 29.25  ? 94   ARG A CA    1 
ATOM   701   C C     . ARG A 1 94   ? 219.901 319.216 271.645 1.00 29.25  ? 94   ARG A C     1 
ATOM   702   O O     . ARG A 1 94   ? 219.170 318.852 272.573 1.00 29.25  ? 94   ARG A O     1 
ATOM   703   C CB    . ARG A 1 94   ? 222.007 319.870 272.827 1.00 29.25  ? 94   ARG A CB    1 
ATOM   704   C CG    . ARG A 1 94   ? 223.429 319.497 273.212 1.00 29.25  ? 94   ARG A CG    1 
ATOM   705   C CD    . ARG A 1 94   ? 223.556 319.217 274.700 1.00 29.25  ? 94   ARG A CD    1 
ATOM   706   N NE    . ARG A 1 94   ? 224.941 318.974 275.087 1.00 29.25  ? 94   ARG A NE    1 
ATOM   707   C CZ    . ARG A 1 94   ? 225.352 318.800 276.336 1.00 29.25  ? 94   ARG A CZ    1 
ATOM   708   N NH1   . ARG A 1 94   ? 224.507 318.835 277.353 1.00 29.25  ? 94   ARG A NH1   1 
ATOM   709   N NH2   . ARG A 1 94   ? 226.643 318.583 276.570 1.00 29.25  ? 94   ARG A NH2   1 
ATOM   710   N N     . GLN A 1 95   ? 219.421 319.817 270.556 1.00 36.73  ? 95   GLN A N     1 
ATOM   711   C CA    . GLN A 1 95   ? 217.999 320.062 270.338 1.00 36.73  ? 95   GLN A CA    1 
ATOM   712   C C     . GLN A 1 95   ? 217.484 319.292 269.123 1.00 36.73  ? 95   GLN A C     1 
ATOM   713   O O     . GLN A 1 95   ? 216.720 319.816 268.304 1.00 36.73  ? 95   GLN A O     1 
ATOM   714   C CB    . GLN A 1 95   ? 217.721 321.556 270.187 1.00 36.73  ? 95   GLN A CB    1 
ATOM   715   C CG    . GLN A 1 95   ? 218.256 322.400 271.333 1.00 36.73  ? 95   GLN A CG    1 
ATOM   716   C CD    . GLN A 1 95   ? 217.159 323.144 272.070 1.00 36.73  ? 95   GLN A CD    1 
ATOM   717   O OE1   . GLN A 1 95   ? 216.110 322.578 272.380 1.00 36.73  ? 95   GLN A OE1   1 
ATOM   718   N NE2   . GLN A 1 95   ? 217.396 324.419 272.355 1.00 36.73  ? 95   GLN A NE2   1 
ATOM   719   N N     . VAL A 1 96   ? 217.903 318.029 268.998 1.00 34.64  ? 96   VAL A N     1 
ATOM   720   C CA    . VAL A 1 96   ? 217.457 317.193 267.885 1.00 34.64  ? 96   VAL A CA    1 
ATOM   721   C C     . VAL A 1 96   ? 215.950 316.981 267.943 1.00 34.64  ? 96   VAL A C     1 
ATOM   722   O O     . VAL A 1 96   ? 215.268 316.981 266.910 1.00 34.64  ? 96   VAL A O     1 
ATOM   723   C CB    . VAL A 1 96   ? 218.223 315.855 267.882 1.00 34.64  ? 96   VAL A CB    1 
ATOM   724   C CG1   . VAL A 1 96   ? 217.393 314.754 267.236 1.00 34.64  ? 96   VAL A CG1   1 
ATOM   725   C CG2   . VAL A 1 96   ? 219.544 316.004 267.148 1.00 34.64  ? 96   VAL A CG2   1 
ATOM   726   N N     . ASP A 1 97   ? 215.405 316.790 269.148 1.00 40.94  ? 97   ASP A N     1 
ATOM   727   C CA    . ASP A 1 97   ? 213.966 316.590 269.282 1.00 40.94  ? 97   ASP A CA    1 
ATOM   728   C C     . ASP A 1 97   ? 213.190 317.805 268.788 1.00 40.94  ? 97   ASP A C     1 
ATOM   729   O O     . ASP A 1 97   ? 212.202 317.663 268.057 1.00 40.94  ? 97   ASP A O     1 
ATOM   730   C CB    . ASP A 1 97   ? 213.612 316.278 270.737 1.00 40.94  ? 97   ASP A CB    1 
ATOM   731   C CG    . ASP A 1 97   ? 214.173 317.301 271.706 1.00 40.94  ? 97   ASP A CG    1 
ATOM   732   O OD1   . ASP A 1 97   ? 215.316 317.759 271.494 1.00 40.94  ? 97   ASP A OD1   1 
ATOM   733   O OD2   . ASP A 1 97   ? 213.471 317.650 272.678 1.00 40.94  ? 97   ASP A OD2   1 
ATOM   734   N N     . LYS A 1 98   ? 213.628 319.008 269.166 1.00 41.72  ? 98   LYS A N     1 
ATOM   735   C CA    . LYS A 1 98   ? 212.966 320.220 268.691 1.00 41.72  ? 98   LYS A CA    1 
ATOM   736   C C     . LYS A 1 98   ? 213.114 320.374 267.182 1.00 41.72  ? 98   LYS A C     1 
ATOM   737   O O     . LYS A 1 98   ? 212.161 320.762 266.493 1.00 41.72  ? 98   LYS A O     1 
ATOM   738   C CB    . LYS A 1 98   ? 213.531 321.443 269.414 1.00 41.72  ? 98   LYS A CB    1 
ATOM   739   C CG    . LYS A 1 98   ? 212.544 322.123 270.350 1.00 41.72  ? 98   LYS A CG    1 
ATOM   740   C CD    . LYS A 1 98   ? 212.458 321.400 271.684 1.00 41.72  ? 98   LYS A CD    1 
ATOM   741   C CE    . LYS A 1 98   ? 211.283 321.902 272.507 1.00 41.72  ? 98   LYS A CE    1 
ATOM   742   N NZ    . LYS A 1 98   ? 211.345 323.374 272.722 1.00 41.72  ? 98   LYS A NZ    1 
ATOM   743   N N     . VAL A 1 99   ? 214.302 320.071 266.651 1.00 37.41  ? 99   VAL A N     1 
ATOM   744   C CA    . VAL A 1 99   ? 214.525 320.183 265.211 1.00 37.41  ? 99   VAL A CA    1 
ATOM   745   C C     . VAL A 1 99   ? 213.586 319.251 264.454 1.00 37.41  ? 99   VAL A C     1 
ATOM   746   O O     . VAL A 1 99   ? 212.998 319.630 263.434 1.00 37.41  ? 99   VAL A O     1 
ATOM   747   C CB    . VAL A 1 99   ? 216.003 319.903 264.880 1.00 37.41  ? 99   VAL A CB    1 
ATOM   748   C CG1   . VAL A 1 99   ? 216.150 319.351 263.467 1.00 37.41  ? 99   VAL A CG1   1 
ATOM   749   C CG2   . VAL A 1 99   ? 216.834 321.166 265.056 1.00 37.41  ? 99   VAL A CG2   1 
ATOM   750   N N     . GLU A 1 100  ? 213.423 318.028 264.946 1.00 43.98  ? 100  GLU A N     1 
ATOM   751   C CA    . GLU A 1 100  ? 212.528 317.055 264.330 1.00 43.98  ? 100  GLU A CA    1 
ATOM   752   C C     . GLU A 1 100  ? 211.068 317.490 264.449 1.00 43.98  ? 100  GLU A C     1 
ATOM   753   O O     . GLU A 1 100  ? 210.290 317.344 263.506 1.00 43.98  ? 100  GLU A O     1 
ATOM   754   C CB    . GLU A 1 100  ? 212.723 315.677 264.969 1.00 43.98  ? 100  GLU A CB    1 
ATOM   755   C CG    . GLU A 1 100  ? 211.740 314.613 264.504 1.00 43.98  ? 100  GLU A CG    1 
ATOM   756   C CD    . GLU A 1 100  ? 211.768 314.404 263.002 1.00 43.98  ? 100  GLU A CD    1 
ATOM   757   O OE1   . GLU A 1 100  ? 212.714 313.756 262.508 1.00 43.98  ? 100  GLU A OE1   1 
ATOM   758   O OE2   . GLU A 1 100  ? 210.839 314.879 262.315 1.00 43.98  ? 100  GLU A OE2   1 
HETATM 759   N N     . SEP A 1 101  ? 210.612 318.119 265.453 1.00 52.69  ? 101  SEP A N     1 
HETATM 760   C CA    . SEP A 1 101  ? 209.191 318.386 265.424 1.00 52.69  ? 101  SEP A CA    1 
HETATM 761   C CB    . SEP A 1 101  ? 208.659 318.558 266.789 1.00 52.69  ? 101  SEP A CB    1 
HETATM 762   O OG    . SEP A 1 101  ? 208.498 317.239 267.269 1.00 52.69  ? 101  SEP A OG    1 
HETATM 763   C C     . SEP A 1 101  ? 208.883 319.633 264.784 1.00 52.69  ? 101  SEP A C     1 
HETATM 764   O O     . SEP A 1 101  ? 207.754 319.843 264.371 1.00 52.69  ? 101  SEP A O     1 
HETATM 765   P P     . SEP A 1 101  ? 209.284 316.823 268.593 1.00 52.69  ? 101  SEP A P     1 
HETATM 766   O O1P   . SEP A 1 101  ? 208.219 316.302 269.518 1.00 52.69  ? 101  SEP A O1P   1 
HETATM 767   O O2P   . SEP A 1 101  ? 210.262 315.773 268.141 1.00 52.69  ? 101  SEP A O2P   1 
HETATM 768   O O3P   . SEP A 1 101  ? 209.873 318.137 269.030 1.00 52.69  ? 101  SEP A O3P   1 
ATOM   769   N N     . PHE A 1 102  ? 209.834 320.520 264.720 1.00 47.39  ? 102  PHE A N     1 
ATOM   770   C CA    . PHE A 1 102  ? 209.510 321.736 263.976 1.00 47.39  ? 102  PHE A CA    1 
ATOM   771   C C     . PHE A 1 102  ? 209.091 321.384 262.546 1.00 47.39  ? 102  PHE A C     1 
ATOM   772   O O     . PHE A 1 102  ? 208.257 322.070 261.952 1.00 47.39  ? 102  PHE A O     1 
ATOM   773   C CB    . PHE A 1 102  ? 210.707 322.702 263.985 1.00 47.39  ? 102  PHE A CB    1 
ATOM   774   C CG    . PHE A 1 102  ? 210.441 324.036 263.320 1.00 47.39  ? 102  PHE A CG    1 
ATOM   775   C CD1   . PHE A 1 102  ? 210.333 324.154 261.942 1.00 47.39  ? 102  PHE A CD1   1 
ATOM   776   C CD2   . PHE A 1 102  ? 210.355 325.186 264.086 1.00 47.39  ? 102  PHE A CD2   1 
ATOM   777   C CE1   . PHE A 1 102  ? 210.102 325.381 261.350 1.00 47.39  ? 102  PHE A CE1   1 
ATOM   778   C CE2   . PHE A 1 102  ? 210.125 326.417 263.499 1.00 47.39  ? 102  PHE A CE2   1 
ATOM   779   C CZ    . PHE A 1 102  ? 210.000 326.514 262.129 1.00 47.39  ? 102  PHE A CZ    1 
ATOM   780   N N     . LYS A 1 103  ? 209.657 320.297 262.012 1.00 41.90  ? 103  LYS A N     1 
ATOM   781   C CA    . LYS A 1 103  ? 209.430 319.938 260.614 1.00 41.90  ? 103  LYS A CA    1 
ATOM   782   C C     . LYS A 1 103  ? 207.949 319.749 260.310 1.00 41.90  ? 103  LYS A C     1 
ATOM   783   O O     . LYS A 1 103  ? 207.485 320.078 259.212 1.00 41.90  ? 103  LYS A O     1 
ATOM   784   C CB    . LYS A 1 103  ? 210.214 318.671 260.269 1.00 41.90  ? 103  LYS A CB    1 
ATOM   785   C CG    . LYS A 1 103  ? 211.709 318.896 260.108 1.00 41.90  ? 103  LYS A CG    1 
ATOM   786   C CD    . LYS A 1 103  ? 212.335 317.844 259.209 1.00 41.90  ? 103  LYS A CD    1 
ATOM   787   C CE    . LYS A 1 103  ? 212.039 316.444 259.721 1.00 41.90  ? 103  LYS A CE    1 
ATOM   788   N NZ    . LYS A 1 103  ? 213.201 315.530 259.543 1.00 41.90  ? 103  LYS A NZ    1 
ATOM   789   N N     . TYR A 1 104  ? 207.191 319.219 261.264 1.00 51.69  ? 104  TYR A N     1 
ATOM   790   C CA    . TYR A 1 104  ? 205.746 319.108 261.110 1.00 51.69  ? 104  TYR A CA    1 
ATOM   791   C C     . TYR A 1 104  ? 205.045 320.150 261.975 1.00 51.69  ? 104  TYR A C     1 
ATOM   792   O O     . TYR A 1 104  ? 205.340 320.276 263.164 1.00 51.69  ? 104  TYR A O     1 
ATOM   793   C CB    . TYR A 1 104  ? 205.265 317.701 261.468 1.00 51.69  ? 104  TYR A CB    1 
ATOM   794   C CG    . TYR A 1 104  ? 206.087 316.597 260.841 1.00 51.69  ? 104  TYR A CG    1 
ATOM   795   C CD1   . TYR A 1 104  ? 205.822 316.158 259.550 1.00 51.69  ? 104  TYR A CD1   1 
ATOM   796   C CD2   . TYR A 1 104  ? 207.124 315.993 261.539 1.00 51.69  ? 104  TYR A CD2   1 
ATOM   797   C CE1   . TYR A 1 104  ? 206.569 315.150 258.972 1.00 51.69  ? 104  TYR A CE1   1 
ATOM   798   C CE2   . TYR A 1 104  ? 207.876 314.984 260.969 1.00 51.69  ? 104  TYR A CE2   1 
ATOM   799   C CZ    . TYR A 1 104  ? 207.595 314.567 259.686 1.00 51.69  ? 104  TYR A CZ    1 
ATOM   800   O OH    . TYR A 1 104  ? 208.341 313.562 259.114 1.00 51.69  ? 104  TYR A OH    1 
HETATM 801   N N     . SEP A 1 105  ? 204.121 320.888 261.363 1.00 78.85  ? 105  SEP A N     1 
HETATM 802   C CA    . SEP A 1 105  ? 203.422 321.993 262.018 1.00 78.85  ? 105  SEP A CA    1 
HETATM 803   C CB    . SEP A 1 105  ? 202.526 321.479 263.148 1.00 78.85  ? 105  SEP A CB    1 
HETATM 804   O OG    . SEP A 1 105  ? 201.507 320.631 262.647 1.00 78.85  ? 105  SEP A OG    1 
HETATM 805   C C     . SEP A 1 105  ? 204.409 323.028 262.553 1.00 78.85  ? 105  SEP A C     1 
HETATM 806   O O     . SEP A 1 105  ? 204.742 323.028 263.738 1.00 78.85  ? 105  SEP A O     1 
HETATM 807   P P     . SEP A 1 105  ? 200.708 319.951 263.869 1.00 78.85  ? 105  SEP A P     1 
HETATM 808   O O1P   . SEP A 1 105  ? 200.360 321.070 264.972 1.00 78.85  ? 105  SEP A O1P   1 
HETATM 809   O O2P   . SEP A 1 105  ? 199.344 319.296 263.320 1.00 78.85  ? 105  SEP A O2P   1 
HETATM 810   O O3P   . SEP A 1 105  ? 201.623 318.808 264.538 1.00 78.85  ? 105  SEP A O3P   1 
ATOM   811   N N     . GLN A 1 106  ? 204.871 323.905 261.667 1.00 67.41  ? 106  GLN A N     1 
ATOM   812   C CA    . GLN A 1 106  ? 205.851 324.924 262.024 1.00 67.41  ? 106  GLN A CA    1 
ATOM   813   C C     . GLN A 1 106  ? 205.272 325.935 263.009 1.00 67.41  ? 106  GLN A C     1 
ATOM   814   O O     . GLN A 1 106  ? 204.298 326.624 262.705 1.00 67.41  ? 106  GLN A O     1 
ATOM   815   C CB    . GLN A 1 106  ? 206.351 325.643 260.770 1.00 67.41  ? 106  GLN A CB    1 
ATOM   816   C CG    . GLN A 1 106  ? 206.995 324.724 259.744 1.00 67.41  ? 106  GLN A CG    1 
ATOM   817   C CD    . GLN A 1 106  ? 206.094 324.459 258.554 1.00 67.41  ? 106  GLN A CD    1 
ATOM   818   O OE1   . GLN A 1 106  ? 204.869 324.448 258.678 1.00 67.41  ? 106  GLN A OE1   1 
ATOM   819   N NE2   . GLN A 1 106  ? 206.697 324.244 257.391 1.00 67.41  ? 106  GLN A NE2   1 
HETATM 820   N N     . SEP A 1 107  ? 205.877 326.018 264.190 1.00 67.05  ? 107  SEP A N     1 
HETATM 821   C CA    . SEP A 1 107  ? 205.416 326.938 265.223 1.00 67.05  ? 107  SEP A CA    1 
HETATM 822   C CB    . SEP A 1 107  ? 204.515 326.212 266.223 1.00 67.05  ? 107  SEP A CB    1 
HETATM 823   O OG    . SEP A 1 107  ? 203.975 327.113 267.172 1.00 67.05  ? 107  SEP A OG    1 
HETATM 824   C C     . SEP A 1 107  ? 206.591 327.588 265.948 1.00 67.05  ? 107  SEP A C     1 
HETATM 825   O O     . SEP A 1 107  ? 207.740 327.181 265.779 1.00 67.05  ? 107  SEP A O     1 
HETATM 826   P P     . SEP A 1 107  ? 202.882 326.358 268.082 1.00 67.05  ? 107  SEP A P     1 
HETATM 827   O O1P   . SEP A 1 107  ? 203.598 325.180 268.913 1.00 67.05  ? 107  SEP A O1P   1 
HETATM 828   O O2P   . SEP A 1 107  ? 202.216 327.409 269.104 1.00 67.05  ? 107  SEP A O2P   1 
HETATM 829   O O3P   . SEP A 1 107  ? 201.738 325.731 267.138 1.00 67.05  ? 107  SEP A O3P   1 
ATOM   830   N N     . THR A 1 108  ? 206.293 328.600 266.758 1.00 60.86  ? 108  THR A N     1 
ATOM   831   C CA    . THR A 1 108  ? 207.324 329.333 267.485 1.00 60.86  ? 108  THR A CA    1 
ATOM   832   C C     . THR A 1 108  ? 207.837 328.539 268.683 1.00 60.86  ? 108  THR A C     1 
ATOM   833   O O     . THR A 1 108  ? 208.942 328.779 269.170 1.00 60.86  ? 108  THR A O     1 
ATOM   834   C CB    . THR A 1 108  ? 206.802 330.696 267.977 1.00 60.86  ? 108  THR A CB    1 
ATOM   835   O OG1   . THR A 1 108  ? 205.674 330.496 268.838 1.00 60.86  ? 108  THR A OG1   1 
ATOM   836   C CG2   . THR A 1 108  ? 206.385 331.563 266.800 1.00 60.86  ? 108  THR A CG2   1 
ATOM   837   N N     . LYS A 1 109  ? 207.029 327.593 269.152 1.00 58.73  ? 109  LYS A N     1 
ATOM   838   C CA    . LYS A 1 109  ? 207.368 326.781 270.312 1.00 58.73  ? 109  LYS A CA    1 
ATOM   839   C C     . LYS A 1 109  ? 208.084 325.487 269.948 1.00 58.73  ? 109  LYS A C     1 
ATOM   840   O O     . LYS A 1 109  ? 208.366 324.681 270.841 1.00 58.73  ? 109  LYS A O     1 
ATOM   841   C CB    . LYS A 1 109  ? 206.103 326.452 271.113 1.00 58.73  ? 109  LYS A CB    1 
ATOM   842   C CG    . LYS A 1 109  ? 205.117 327.604 271.225 1.00 58.73  ? 109  LYS A CG    1 
ATOM   843   C CD    . LYS A 1 109  ? 204.280 327.498 272.492 1.00 58.73  ? 109  LYS A CD    1 
ATOM   844   C CE    . LYS A 1 109  ? 203.604 326.139 272.607 1.00 58.73  ? 109  LYS A CE    1 
ATOM   845   N NZ    . LYS A 1 109  ? 202.887 325.756 271.358 1.00 58.73  ? 109  LYS A NZ    1 
ATOM   846   N N     . ASP A 1 110  ? 208.384 325.267 268.672 1.00 52.08  ? 110  ASP A N     1 
ATOM   847   C CA    . ASP A 1 110  ? 208.966 324.003 268.239 1.00 52.08  ? 110  ASP A CA    1 
ATOM   848   C C     . ASP A 1 110  ? 210.398 324.167 267.734 1.00 52.08  ? 110  ASP A C     1 
ATOM   849   O O     . ASP A 1 110  ? 211.092 323.181 267.489 1.00 52.08  ? 110  ASP A O     1 
ATOM   850   C CB    . ASP A 1 110  ? 208.098 323.373 267.148 1.00 52.08  ? 110  ASP A CB    1 
ATOM   851   C CG    . ASP A 1 110  ? 207.266 322.217 267.664 1.00 52.08  ? 110  ASP A CG    1 
ATOM   852   O OD1   . ASP A 1 110  ? 206.945 322.207 268.871 1.00 52.08  ? 110  ASP A OD1   1 
ATOM   853   O OD2   . ASP A 1 110  ? 206.929 321.319 266.864 1.00 52.08  ? 110  ASP A OD2   1 
HETATM 854   N N     . SEP A 1 111  ? 210.838 325.412 267.583 1.00 46.91  ? 111  SEP A N     1 
HETATM 855   C CA    . SEP A 1 111  ? 212.180 325.688 267.082 1.00 46.91  ? 111  SEP A CA    1 
HETATM 856   C CB    . SEP A 1 111  ? 212.220 327.045 266.378 1.00 46.91  ? 111  SEP A CB    1 
HETATM 857   C C     . SEP A 1 111  ? 213.217 325.654 268.198 1.00 46.91  ? 111  SEP A C     1 
HETATM 858   O O     . SEP A 1 111  ? 212.882 325.780 269.375 1.00 46.91  ? 111  SEP A O     1 
ATOM   859   N N     . LEU A 1 112  ? 214.479 325.482 267.817 1.00 43.00  ? 112  LEU A N     1 
ATOM   860   C CA    . LEU A 1 112  ? 215.574 325.461 268.780 1.00 43.00  ? 112  LEU A CA    1 
ATOM   861   C C     . LEU A 1 112  ? 215.793 326.849 269.371 1.00 43.00  ? 112  LEU A C     1 
ATOM   862   O O     . LEU A 1 112  ? 215.526 327.860 268.720 1.00 43.00  ? 112  LEU A O     1 
ATOM   863   C CB    . LEU A 1 112  ? 216.859 324.947 268.124 1.00 43.00  ? 112  LEU A CB    1 
ATOM   864   C CG    . LEU A 1 112  ? 217.398 325.716 266.914 1.00 43.00  ? 112  LEU A CG    1 
ATOM   865   C CD1   . LEU A 1 112  ? 218.508 326.677 267.320 1.00 43.00  ? 112  LEU A CD1   1 
ATOM   866   C CD2   . LEU A 1 112  ? 217.886 324.751 265.844 1.00 43.00  ? 112  LEU A CD2   1 
ATOM   867   N N     . HIS A 1 113  ? 216.277 326.891 270.609 1.00 44.84  ? 113  HIS A N     1 
ATOM   868   C CA    . HIS A 1 113  ? 216.500 328.163 271.281 1.00 44.84  ? 113  HIS A CA    1 
ATOM   869   C C     . HIS A 1 113  ? 217.662 328.913 270.642 1.00 44.84  ? 113  HIS A C     1 
ATOM   870   O O     . HIS A 1 113  ? 218.735 328.350 270.410 1.00 44.84  ? 113  HIS A O     1 
ATOM   871   C CB    . HIS A 1 113  ? 216.773 327.938 272.768 1.00 44.84  ? 113  HIS A CB    1 
ATOM   872   C CG    . HIS A 1 113  ? 215.663 327.238 273.488 1.00 44.84  ? 113  HIS A CG    1 
ATOM   873   N ND1   . HIS A 1 113  ? 215.797 326.755 274.772 1.00 44.84  ? 113  HIS A ND1   1 
ATOM   874   C CD2   . HIS A 1 113  ? 214.398 326.941 273.105 1.00 44.84  ? 113  HIS A CD2   1 
ATOM   875   C CE1   . HIS A 1 113  ? 214.664 326.189 275.148 1.00 44.84  ? 113  HIS A CE1   1 
ATOM   876   N NE2   . HIS A 1 113  ? 213.799 326.289 274.155 1.00 44.84  ? 113  HIS A NE2   1 
ATOM   877   N N     . ALA A 1 114  ? 217.440 330.197 270.357 1.00 36.53  ? 114  ALA A N     1 
ATOM   878   C CA    . ALA A 1 114  ? 218.494 331.026 269.787 1.00 36.53  ? 114  ALA A CA    1 
ATOM   879   C C     . ALA A 1 114  ? 219.568 331.366 270.810 1.00 36.53  ? 114  ALA A C     1 
ATOM   880   O O     . ALA A 1 114  ? 220.734 331.545 270.442 1.00 36.53  ? 114  ALA A O     1 
ATOM   881   C CB    . ALA A 1 114  ? 217.900 332.309 269.204 1.00 36.53  ? 114  ALA A CB    1 
ATOM   882   N N     . LYS A 1 115  ? 219.201 331.457 272.086 1.00 37.47  ? 115  LYS A N     1 
ATOM   883   C CA    . LYS A 1 115  ? 220.145 331.773 273.152 1.00 37.47  ? 115  LYS A CA    1 
ATOM   884   C C     . LYS A 1 115  ? 220.726 330.471 273.690 1.00 37.47  ? 115  LYS A C     1 
ATOM   885   O O     . LYS A 1 115  ? 220.004 329.651 274.266 1.00 37.47  ? 115  LYS A O     1 
ATOM   886   C CB    . LYS A 1 115  ? 219.460 332.568 274.260 1.00 37.47  ? 115  LYS A CB    1 
ATOM   887   C CG    . LYS A 1 115  ? 219.428 334.067 274.023 1.00 37.47  ? 115  LYS A CG    1 
ATOM   888   C CD    . LYS A 1 115  ? 218.822 334.799 275.209 1.00 37.47  ? 115  LYS A CD    1 
ATOM   889   C CE    . LYS A 1 115  ? 219.849 335.008 276.309 1.00 37.47  ? 115  LYS A CE    1 
ATOM   890   N NZ    . LYS A 1 115  ? 219.331 334.608 277.645 1.00 37.47  ? 115  LYS A NZ    1 
ATOM   891   N N     . TYR A 1 116  ? 222.029 330.282 273.502 1.00 37.04  ? 116  TYR A N     1 
ATOM   892   C CA    . TYR A 1 116  ? 222.734 329.107 273.990 1.00 37.04  ? 116  TYR A CA    1 
ATOM   893   C C     . TYR A 1 116  ? 223.717 329.518 275.077 1.00 37.04  ? 116  TYR A C     1 
ATOM   894   O O     . TYR A 1 116  ? 224.420 330.525 274.945 1.00 37.04  ? 116  TYR A O     1 
ATOM   895   C CB    . TYR A 1 116  ? 223.465 328.390 272.852 1.00 37.04  ? 116  TYR A CB    1 
ATOM   896   C CG    . TYR A 1 116  ? 222.587 327.430 272.081 1.00 37.04  ? 116  TYR A CG    1 
ATOM   897   C CD1   . TYR A 1 116  ? 221.977 326.355 272.714 1.00 37.04  ? 116  TYR A CD1   1 
ATOM   898   C CD2   . TYR A 1 116  ? 222.361 327.603 270.721 1.00 37.04  ? 116  TYR A CD2   1 
ATOM   899   C CE1   . TYR A 1 116  ? 221.171 325.476 272.015 1.00 37.04  ? 116  TYR A CE1   1 
ATOM   900   C CE2   . TYR A 1 116  ? 221.556 326.729 270.013 1.00 37.04  ? 116  TYR A CE2   1 
ATOM   901   C CZ    . TYR A 1 116  ? 220.964 325.668 270.665 1.00 37.04  ? 116  TYR A CZ    1 
ATOM   902   O OH    . TYR A 1 116  ? 220.162 324.795 269.966 1.00 37.04  ? 116  TYR A OH    1 
ATOM   903   N N     . ASN A 1 117  ? 223.760 328.734 276.150 1.00 39.12  ? 117  ASN A N     1 
ATOM   904   C CA    . ASN A 1 117  ? 224.545 329.095 277.318 1.00 39.12  ? 117  ASN A CA    1 
ATOM   905   C C     . ASN A 1 117  ? 226.035 328.856 277.062 1.00 39.12  ? 117  ASN A C     1 
ATOM   906   O O     . ASN A 1 117  ? 226.460 328.460 275.973 1.00 39.12  ? 117  ASN A O     1 
ATOM   907   C CB    . ASN A 1 117  ? 224.069 328.301 278.538 1.00 39.12  ? 117  ASN A CB    1 
ATOM   908   C CG    . ASN A 1 117  ? 224.487 328.933 279.853 1.00 39.12  ? 117  ASN A CG    1 
ATOM   909   O OD1   . ASN A 1 117  ? 224.803 330.121 279.912 1.00 39.12  ? 117  ASN A OD1   1 
ATOM   910   N ND2   . ASN A 1 117  ? 224.494 328.136 280.916 1.00 39.12  ? 117  ASN A ND2   1 
ATOM   911   N N     . THR A 1 118  ? 226.831 329.107 278.101 1.00 40.79  ? 118  THR A N     1 
ATOM   912   C CA    . THR A 1 118  ? 228.273 328.900 278.086 1.00 40.79  ? 118  THR A CA    1 
ATOM   913   C C     . THR A 1 118  ? 228.605 327.426 278.280 1.00 40.79  ? 118  THR A C     1 
ATOM   914   O O     . THR A 1 118  ? 227.755 326.560 278.046 1.00 40.79  ? 118  THR A O     1 
ATOM   915   C CB    . THR A 1 118  ? 228.958 329.745 279.163 1.00 40.79  ? 118  THR A CB    1 
ATOM   916   O OG1   . THR A 1 118  ? 228.436 329.398 280.452 1.00 40.79  ? 118  THR A OG1   1 
ATOM   917   C CG2   . THR A 1 118  ? 228.733 331.226 278.903 1.00 40.79  ? 118  THR A CG2   1 
ATOM   918   N N     . LYS A 1 119  ? 229.853 327.145 278.663 1.00 40.64  ? 119  LYS A N     1 
ATOM   919   C CA    . LYS A 1 119  ? 230.361 325.785 278.818 1.00 40.64  ? 119  LYS A CA    1 
ATOM   920   C C     . LYS A 1 119  ? 229.372 324.884 279.549 1.00 40.64  ? 119  LYS A C     1 
ATOM   921   O O     . LYS A 1 119  ? 228.581 325.344 280.378 1.00 40.64  ? 119  LYS A O     1 
ATOM   922   C CB    . LYS A 1 119  ? 231.696 325.812 279.569 1.00 40.64  ? 119  LYS A CB    1 
ATOM   923   C CG    . LYS A 1 119  ? 231.593 326.322 280.997 1.00 40.64  ? 119  LYS A CG    1 
ATOM   924   C CD    . LYS A 1 119  ? 232.579 327.450 281.256 1.00 40.64  ? 119  LYS A CD    1 
ATOM   925   C CE    . LYS A 1 119  ? 232.341 328.089 282.614 1.00 40.64  ? 119  LYS A CE    1 
ATOM   926   N NZ    . LYS A 1 119  ? 231.052 328.833 282.659 1.00 40.64  ? 119  LYS A NZ    1 
ATOM   927   N N     . THR A 1 120  ? 229.441 323.590 279.226 1.00 40.11  ? 120  THR A N     1 
ATOM   928   C CA    . THR A 1 120  ? 228.503 322.497 279.514 1.00 40.11  ? 120  THR A CA    1 
ATOM   929   C C     . THR A 1 120  ? 227.321 322.515 278.548 1.00 40.11  ? 120  THR A C     1 
ATOM   930   O O     . THR A 1 120  ? 226.493 321.597 278.604 1.00 40.11  ? 120  THR A O     1 
ATOM   931   C CB    . THR A 1 120  ? 227.967 322.480 280.958 1.00 40.11  ? 120  THR A CB    1 
ATOM   932   O OG1   . THR A 1 120  ? 227.034 323.552 281.143 1.00 40.11  ? 120  THR A OG1   1 
ATOM   933   C CG2   . THR A 1 120  ? 229.105 322.594 281.971 1.00 40.11  ? 120  THR A CG2   1 
ATOM   934   N N     . CYS A 1 121  ? 227.228 323.507 277.664 1.00 34.05  ? 121  CYS A N     1 
ATOM   935   C CA    . CYS A 1 121  ? 226.310 323.516 276.522 1.00 34.05  ? 121  CYS A CA    1 
ATOM   936   C C     . CYS A 1 121  ? 224.888 323.121 276.921 1.00 34.05  ? 121  CYS A C     1 
ATOM   937   O O     . CYS A 1 121  ? 224.342 322.109 276.481 1.00 34.05  ? 121  CYS A O     1 
ATOM   938   C CB    . CYS A 1 121  ? 226.834 322.611 275.408 1.00 34.05  ? 121  CYS A CB    1 
ATOM   939   S SG    . CYS A 1 121  ? 228.431 323.117 274.727 1.00 34.05  ? 121  CYS A SG    1 
ATOM   940   N N     . ALA A 1 122  ? 224.290 323.948 277.770 1.00 39.23  ? 122  ALA A N     1 
ATOM   941   C CA    . ALA A 1 122  ? 222.931 323.734 278.244 1.00 39.23  ? 122  ALA A CA    1 
ATOM   942   C C     . ALA A 1 122  ? 222.042 324.893 277.812 1.00 39.23  ? 122  ALA A C     1 
ATOM   943   O O     . ALA A 1 122  ? 222.499 325.876 277.224 1.00 39.23  ? 122  ALA A O     1 
ATOM   944   C CB    . ALA A 1 122  ? 222.896 323.572 279.769 1.00 39.23  ? 122  ALA A CB    1 
ATOM   945   N N     . THR A 1 123  ? 220.750 324.758 278.100 1.00 38.87  ? 123  THR A N     1 
ATOM   946   C CA    . THR A 1 123  ? 219.808 325.833 277.821 1.00 38.87  ? 123  THR A CA    1 
ATOM   947   C C     . THR A 1 123  ? 219.810 326.843 278.962 1.00 38.87  ? 123  THR A C     1 
ATOM   948   O O     . THR A 1 123  ? 219.848 326.475 280.139 1.00 38.87  ? 123  THR A O     1 
ATOM   949   C CB    . THR A 1 123  ? 218.401 325.274 277.615 1.00 38.87  ? 123  THR A CB    1 
ATOM   950   O OG1   . THR A 1 123  ? 218.034 324.468 278.741 1.00 38.87  ? 123  THR A OG1   1 
ATOM   951   C CG2   . THR A 1 123  ? 218.344 324.427 276.351 1.00 38.87  ? 123  THR A CG2   1 
ATOM   952   N N     . VAL A 1 124  ? 219.768 328.126 278.607 1.00 40.36  ? 124  VAL A N     1 
ATOM   953   C CA    . VAL A 1 124  ? 219.847 329.204 279.589 1.00 40.36  ? 124  VAL A CA    1 
ATOM   954   C C     . VAL A 1 124  ? 218.493 329.831 279.890 1.00 40.36  ? 124  VAL A C     1 
ATOM   955   O O     . VAL A 1 124  ? 218.295 330.327 281.012 1.00 40.36  ? 124  VAL A O     1 
ATOM   956   C CB    . VAL A 1 124  ? 220.853 330.291 279.149 1.00 40.36  ? 124  VAL A CB    1 
ATOM   957   C CG1   . VAL A 1 124  ? 220.344 331.044 277.926 1.00 40.36  ? 124  VAL A CG1   1 
ATOM   958   C CG2   . VAL A 1 124  ? 221.166 331.245 280.297 1.00 40.36  ? 124  VAL A CG2   1 
ATOM   959   N N     . VAL A 1 125  ? 217.549 329.809 278.948 1.00 44.53  ? 125  VAL A N     1 
ATOM   960   C CA    . VAL A 1 125  ? 216.239 330.414 279.139 1.00 44.53  ? 125  VAL A CA    1 
ATOM   961   C C     . VAL A 1 125  ? 215.164 329.421 278.723 1.00 44.53  ? 125  VAL A C     1 
ATOM   962   O O     . VAL A 1 125  ? 215.425 328.437 278.027 1.00 44.53  ? 125  VAL A O     1 
ATOM   963   C CB    . VAL A 1 125  ? 216.084 331.735 278.355 1.00 44.53  ? 125  VAL A CB    1 
ATOM   964   C CG1   . VAL A 1 125  ? 216.845 332.854 279.048 1.00 44.53  ? 125  VAL A CG1   1 
ATOM   965   C CG2   . VAL A 1 125  ? 216.571 331.562 276.927 1.00 44.53  ? 125  VAL A CG2   1 
ATOM   966   N N     . GLY A 1 126  ? 213.937 329.696 279.163 1.00 53.42  ? 126  GLY A N     1 
ATOM   967   C CA    . GLY A 1 126  ? 212.814 328.831 278.879 1.00 53.42  ? 126  GLY A CA    1 
ATOM   968   C C     . GLY A 1 126  ? 212.300 328.983 277.460 1.00 53.42  ? 126  GLY A C     1 
ATOM   969   O O     . GLY A 1 126  ? 212.801 329.768 276.655 1.00 53.42  ? 126  GLY A O     1 
ATOM   970   N N     . ASP A 1 127  ? 211.265 328.202 277.156 1.00 56.95  ? 127  ASP A N     1 
ATOM   971   C CA    . ASP A 1 127  ? 210.678 328.179 275.823 1.00 56.95  ? 127  ASP A CA    1 
ATOM   972   C C     . ASP A 1 127  ? 209.656 329.286 275.599 1.00 56.95  ? 127  ASP A C     1 
ATOM   973   O O     . ASP A 1 127  ? 209.136 329.407 274.484 1.00 56.95  ? 127  ASP A O     1 
ATOM   974   C CB    . ASP A 1 127  ? 210.024 326.819 275.563 1.00 56.95  ? 127  ASP A CB    1 
ATOM   975   C CG    . ASP A 1 127  ? 210.988 325.664 275.748 1.00 56.95  ? 127  ASP A CG    1 
ATOM   976   O OD1   . ASP A 1 127  ? 211.657 325.282 274.765 1.00 56.95  ? 127  ASP A OD1   1 
ATOM   977   O OD2   . ASP A 1 127  ? 211.078 325.138 276.878 1.00 56.95  ? 127  ASP A OD2   1 
ATOM   978   N N     . ASP A 1 128  ? 209.354 330.092 276.618 1.00 62.47  ? 128  ASP A N     1 
ATOM   979   C CA    . ASP A 1 128  ? 208.383 331.168 276.484 1.00 62.47  ? 128  ASP A CA    1 
ATOM   980   C C     . ASP A 1 128  ? 208.872 332.503 277.028 1.00 62.47  ? 128  ASP A C     1 
ATOM   981   O O     . ASP A 1 128  ? 208.136 333.492 276.941 1.00 62.47  ? 128  ASP A O     1 
ATOM   982   C CB    . ASP A 1 128  ? 207.066 330.791 277.180 1.00 62.47  ? 128  ASP A CB    1 
ATOM   983   C CG    . ASP A 1 128  ? 207.284 330.159 278.540 1.00 62.47  ? 128  ASP A CG    1 
ATOM   984   O OD1   . ASP A 1 128  ? 208.259 329.392 278.690 1.00 62.47  ? 128  ASP A OD1   1 
ATOM   985   O OD2   . ASP A 1 128  ? 206.482 330.427 279.458 1.00 62.47  ? 128  ASP A OD2   1 
ATOM   986   N N     . GLN A 1 129  ? 210.081 332.566 277.582 1.00 61.20  ? 129  GLN A N     1 
ATOM   987   C CA    . GLN A 1 129  ? 210.642 333.812 278.086 1.00 61.20  ? 129  GLN A CA    1 
ATOM   988   C C     . GLN A 1 129  ? 211.488 334.541 277.051 1.00 61.20  ? 129  GLN A C     1 
ATOM   989   O O     . GLN A 1 129  ? 212.057 335.591 277.365 1.00 61.20  ? 129  GLN A O     1 
ATOM   990   C CB    . GLN A 1 129  ? 211.482 333.543 279.340 1.00 61.20  ? 129  GLN A CB    1 
ATOM   991   C CG    . GLN A 1 129  ? 210.696 333.581 280.644 1.00 61.20  ? 129  GLN A CG    1 
ATOM   992   C CD    . GLN A 1 129  ? 209.909 332.307 280.900 1.00 61.20  ? 129  GLN A CD    1 
ATOM   993   O OE1   . GLN A 1 129  ? 209.775 331.456 280.021 1.00 61.20  ? 129  GLN A OE1   1 
ATOM   994   N NE2   . GLN A 1 129  ? 209.384 332.173 282.112 1.00 61.20  ? 129  GLN A NE2   1 
ATOM   995   N N     . TRP A 1 130  ? 211.584 334.012 275.834 1.00 51.13  ? 130  TRP A N     1 
ATOM   996   C CA    . TRP A 1 130  ? 212.380 334.629 274.783 1.00 51.13  ? 130  TRP A CA    1 
ATOM   997   C C     . TRP A 1 130  ? 211.842 334.165 273.438 1.00 51.13  ? 130  TRP A C     1 
ATOM   998   O O     . TRP A 1 130  ? 211.102 333.181 273.352 1.00 51.13  ? 130  TRP A O     1 
ATOM   999   C CB    . TRP A 1 130  ? 213.866 334.277 274.925 1.00 51.13  ? 130  TRP A CB    1 
ATOM   1000  C CG    . TRP A 1 130  ? 214.794 335.287 274.319 1.00 51.13  ? 130  TRP A CG    1 
ATOM   1001  C CD1   . TRP A 1 130  ? 215.247 335.317 273.032 1.00 51.13  ? 130  TRP A CD1   1 
ATOM   1002  C CD2   . TRP A 1 130  ? 215.388 336.412 274.978 1.00 51.13  ? 130  TRP A CD2   1 
ATOM   1003  N NE1   . TRP A 1 130  ? 216.083 336.391 272.848 1.00 51.13  ? 130  TRP A NE1   1 
ATOM   1004  C CE2   . TRP A 1 130  ? 216.187 337.079 274.028 1.00 51.13  ? 130  TRP A CE2   1 
ATOM   1005  C CE3   . TRP A 1 130  ? 215.322 336.920 276.279 1.00 51.13  ? 130  TRP A CE3   1 
ATOM   1006  C CZ2   . TRP A 1 130  ? 216.913 338.228 274.338 1.00 51.13  ? 130  TRP A CZ2   1 
ATOM   1007  C CZ3   . TRP A 1 130  ? 216.043 338.060 276.585 1.00 51.13  ? 130  TRP A CZ3   1 
ATOM   1008  C CH2   . TRP A 1 130  ? 216.828 338.701 275.618 1.00 51.13  ? 130  TRP A CH2   1 
ATOM   1009  N N     . GLY A 1 131  ? 212.222 334.888 272.388 1.00 49.49  ? 131  GLY A N     1 
ATOM   1010  C CA    . GLY A 1 131  ? 211.813 334.517 271.049 1.00 49.49  ? 131  GLY A CA    1 
ATOM   1011  C C     . GLY A 1 131  ? 212.761 333.516 270.425 1.00 49.49  ? 131  GLY A C     1 
ATOM   1012  O O     . GLY A 1 131  ? 213.811 333.888 269.893 1.00 49.49  ? 131  GLY A O     1 
ATOM   1013  N N     . HIS A 1 132  ? 212.399 332.239 270.486 1.00 48.94  ? 132  HIS A N     1 
ATOM   1014  C CA    . HIS A 1 132  ? 213.256 331.160 269.997 1.00 48.94  ? 132  HIS A CA    1 
ATOM   1015  C C     . HIS A 1 132  ? 212.875 330.775 268.569 1.00 48.94  ? 132  HIS A C     1 
ATOM   1016  O O     . HIS A 1 132  ? 212.541 329.629 268.266 1.00 48.94  ? 132  HIS A O     1 
ATOM   1017  C CB    . HIS A 1 132  ? 213.179 329.961 270.937 1.00 48.94  ? 132  HIS A CB    1 
ATOM   1018  C CG    . HIS A 1 132  ? 213.686 330.245 272.316 1.00 48.94  ? 132  HIS A CG    1 
ATOM   1019  N ND1   . HIS A 1 132  ? 214.894 330.864 272.552 1.00 48.94  ? 132  HIS A ND1   1 
ATOM   1020  C CD2   . HIS A 1 132  ? 213.146 329.998 273.533 1.00 48.94  ? 132  HIS A CD2   1 
ATOM   1021  C CE1   . HIS A 1 132  ? 215.078 330.984 273.854 1.00 48.94  ? 132  HIS A CE1   1 
ATOM   1022  N NE2   . HIS A 1 132  ? 214.032 330.466 274.472 1.00 48.94  ? 132  HIS A NE2   1 
ATOM   1023  N N     . LEU A 1 133  ? 212.928 331.766 267.680 1.00 45.52  ? 133  LEU A N     1 
ATOM   1024  C CA    . LEU A 1 133  ? 212.661 331.537 266.261 1.00 45.52  ? 133  LEU A CA    1 
ATOM   1025  C C     . LEU A 1 133  ? 213.479 332.555 265.471 1.00 45.52  ? 133  LEU A C     1 
ATOM   1026  O O     . LEU A 1 133  ? 213.036 333.690 265.271 1.00 45.52  ? 133  LEU A O     1 
ATOM   1027  C CB    . LEU A 1 133  ? 211.175 331.648 265.953 1.00 45.52  ? 133  LEU A CB    1 
ATOM   1028  C CG    . LEU A 1 133  ? 210.738 331.213 264.552 1.00 45.52  ? 133  LEU A CG    1 
ATOM   1029  C CD1   . LEU A 1 133  ? 211.274 329.830 264.222 1.00 45.52  ? 133  LEU A CD1   1 
ATOM   1030  C CD2   . LEU A 1 133  ? 209.224 331.238 264.439 1.00 45.52  ? 133  LEU A CD2   1 
ATOM   1031  N N     . GLN A 1 134  ? 214.666 332.139 265.027 1.00 40.53  ? 134  GLN A N     1 
ATOM   1032  C CA    . GLN A 1 134  ? 215.560 332.988 264.235 1.00 40.53  ? 134  GLN A CA    1 
ATOM   1033  C C     . GLN A 1 134  ? 216.217 332.098 263.182 1.00 40.53  ? 134  GLN A C     1 
ATOM   1034  O O     . GLN A 1 134  ? 217.256 331.482 263.433 1.00 40.53  ? 134  GLN A O     1 
ATOM   1035  C CB    . GLN A 1 134  ? 216.592 333.682 265.114 1.00 40.53  ? 134  GLN A CB    1 
ATOM   1036  C CG    . GLN A 1 134  ? 216.056 334.892 265.860 1.00 40.53  ? 134  GLN A CG    1 
ATOM   1037  C CD    . GLN A 1 134  ? 216.821 335.175 267.136 1.00 40.53  ? 134  GLN A CD    1 
ATOM   1038  O OE1   . GLN A 1 134  ? 218.000 335.528 267.102 1.00 40.53  ? 134  GLN A OE1   1 
ATOM   1039  N NE2   . GLN A 1 134  ? 216.153 335.019 268.273 1.00 40.53  ? 134  GLN A NE2   1 
ATOM   1040  N N     . LEU A 1 135  ? 215.600 332.036 262.000 1.00 38.26  ? 135  LEU A N     1 
ATOM   1041  C CA    . LEU A 1 135  ? 216.152 331.242 260.911 1.00 38.26  ? 135  LEU A CA    1 
ATOM   1042  C C     . LEU A 1 135  ? 217.396 331.879 260.307 1.00 38.26  ? 135  LEU A C     1 
ATOM   1043  O O     . LEU A 1 135  ? 218.172 331.186 259.640 1.00 38.26  ? 135  LEU A O     1 
ATOM   1044  C CB    . LEU A 1 135  ? 215.091 331.033 259.830 1.00 38.26  ? 135  LEU A CB    1 
ATOM   1045  C CG    . LEU A 1 135  ? 213.705 330.653 260.355 1.00 38.26  ? 135  LEU A CG    1 
ATOM   1046  C CD1   . LEU A 1 135  ? 212.682 330.658 259.236 1.00 38.26  ? 135  LEU A CD1   1 
ATOM   1047  C CD2   . LEU A 1 135  ? 213.743 329.297 261.040 1.00 38.26  ? 135  LEU A CD2   1 
ATOM   1048  N N     . ASP A 1 136  ? 217.598 333.181 260.524 1.00 40.03  ? 136  ASP A N     1 
ATOM   1049  C CA    . ASP A 1 136  ? 218.775 333.854 259.985 1.00 40.03  ? 136  ASP A CA    1 
ATOM   1050  C C     . ASP A 1 136  ? 220.060 333.293 260.582 1.00 40.03  ? 136  ASP A C     1 
ATOM   1051  O O     . ASP A 1 136  ? 221.055 333.114 259.871 1.00 40.03  ? 136  ASP A O     1 
ATOM   1052  C CB    . ASP A 1 136  ? 218.676 335.358 260.238 1.00 40.03  ? 136  ASP A CB    1 
ATOM   1053  C CG    . ASP A 1 136  ? 218.318 335.685 261.675 1.00 40.03  ? 136  ASP A CG    1 
ATOM   1054  O OD1   . ASP A 1 136  ? 218.277 334.756 262.509 1.00 40.03  ? 136  ASP A OD1   1 
ATOM   1055  O OD2   . ASP A 1 136  ? 218.074 336.872 261.973 1.00 40.03  ? 136  ASP A OD2   1 
ATOM   1056  N N     . ALA A 1 137  ? 220.062 333.024 261.890 1.00 34.91  ? 137  ALA A N     1 
ATOM   1057  C CA    . ALA A 1 137  ? 221.255 332.486 262.536 1.00 34.91  ? 137  ALA A CA    1 
ATOM   1058  C C     . ALA A 1 137  ? 221.605 331.109 261.984 1.00 34.91  ? 137  ALA A C     1 
ATOM   1059  O O     . ALA A 1 137  ? 222.768 330.826 261.676 1.00 34.91  ? 137  ALA A O     1 
ATOM   1060  C CB    . ALA A 1 137  ? 221.050 332.426 264.050 1.00 34.91  ? 137  ALA A CB    1 
ATOM   1061  N N     . THR A 1 138  ? 220.603 330.239 261.844 1.00 31.71  ? 138  THR A N     1 
ATOM   1062  C CA    . THR A 1 138  ? 220.852 328.916 261.280 1.00 31.71  ? 138  THR A CA    1 
ATOM   1063  C C     . THR A 1 138  ? 221.329 329.017 259.837 1.00 31.71  ? 138  THR A C     1 
ATOM   1064  O O     . THR A 1 138  ? 222.251 328.300 259.427 1.00 31.71  ? 138  THR A O     1 
ATOM   1065  C CB    . THR A 1 138  ? 219.590 328.059 261.367 1.00 31.71  ? 138  THR A CB    1 
ATOM   1066  O OG1   . THR A 1 138  ? 218.868 328.387 262.561 1.00 31.71  ? 138  THR A OG1   1 
ATOM   1067  C CG2   . THR A 1 138  ? 219.953 326.583 261.390 1.00 31.71  ? 138  THR A CG2   1 
ATOM   1068  N N     . SER A 1 139  ? 220.716 329.909 259.054 1.00 33.94  ? 139  SER A N     1 
ATOM   1069  C CA    . SER A 1 139  ? 221.112 330.065 257.659 1.00 33.94  ? 139  SER A CA    1 
ATOM   1070  C C     . SER A 1 139  ? 222.553 330.545 257.541 1.00 33.94  ? 139  SER A C     1 
ATOM   1071  O O     . SER A 1 139  ? 223.326 330.013 256.736 1.00 33.94  ? 139  SER A O     1 
ATOM   1072  C CB    . SER A 1 139  ? 220.165 331.034 256.951 1.00 33.94  ? 139  SER A CB    1 
ATOM   1073  O OG    . SER A 1 139  ? 218.811 330.708 257.216 1.00 33.94  ? 139  SER A OG    1 
ATOM   1074  N N     . VAL A 1 140  ? 222.939 331.541 258.344 1.00 32.17  ? 140  VAL A N     1 
ATOM   1075  C CA    . VAL A 1 140  ? 224.300 332.063 258.261 1.00 32.17  ? 140  VAL A CA    1 
ATOM   1076  C C     . VAL A 1 140  ? 225.301 331.029 258.765 1.00 32.17  ? 140  VAL A C     1 
ATOM   1077  O O     . VAL A 1 140  ? 226.400 330.894 258.212 1.00 32.17  ? 140  VAL A O     1 
ATOM   1078  C CB    . VAL A 1 140  ? 224.418 333.407 259.010 1.00 32.17  ? 140  VAL A CB    1 
ATOM   1079  C CG1   . VAL A 1 140  ? 224.299 333.234 260.514 1.00 32.17  ? 140  VAL A CG1   1 
ATOM   1080  C CG2   . VAL A 1 140  ? 225.724 334.100 258.654 1.00 32.17  ? 140  VAL A CG2   1 
ATOM   1081  N N     . TYR A 1 141  ? 224.936 330.268 259.802 1.00 25.83  ? 141  TYR A N     1 
ATOM   1082  C CA    . TYR A 1 141  ? 225.826 329.224 260.296 1.00 25.83  ? 141  TYR A CA    1 
ATOM   1083  C C     . TYR A 1 141  ? 226.058 328.158 259.234 1.00 25.83  ? 141  TYR A C     1 
ATOM   1084  O O     . TYR A 1 141  ? 227.199 327.751 258.987 1.00 25.83  ? 141  TYR A O     1 
ATOM   1085  C CB    . TYR A 1 141  ? 225.253 328.603 261.570 1.00 25.83  ? 141  TYR A CB    1 
ATOM   1086  C CG    . TYR A 1 141  ? 225.882 327.279 261.941 1.00 25.83  ? 141  TYR A CG    1 
ATOM   1087  C CD1   . TYR A 1 141  ? 227.168 327.222 262.461 1.00 25.83  ? 141  TYR A CD1   1 
ATOM   1088  C CD2   . TYR A 1 141  ? 225.190 326.087 261.773 1.00 25.83  ? 141  TYR A CD2   1 
ATOM   1089  C CE1   . TYR A 1 141  ? 227.749 326.015 262.802 1.00 25.83  ? 141  TYR A CE1   1 
ATOM   1090  C CE2   . TYR A 1 141  ? 225.762 324.875 262.111 1.00 25.83  ? 141  TYR A CE2   1 
ATOM   1091  C CZ    . TYR A 1 141  ? 227.041 324.845 262.625 1.00 25.83  ? 141  TYR A CZ    1 
ATOM   1092  O OH    . TYR A 1 141  ? 227.615 323.641 262.963 1.00 25.83  ? 141  TYR A OH    1 
ATOM   1093  N N     . LEU A 1 142  ? 224.985 327.707 258.577 1.00 29.43  ? 142  LEU A N     1 
ATOM   1094  C CA    . LEU A 1 142  ? 225.131 326.701 257.530 1.00 29.43  ? 142  LEU A CA    1 
ATOM   1095  C C     . LEU A 1 142  ? 225.926 327.243 256.348 1.00 29.43  ? 142  LEU A C     1 
ATOM   1096  O O     . LEU A 1 142  ? 226.777 326.540 255.788 1.00 29.43  ? 142  LEU A O     1 
ATOM   1097  C CB    . LEU A 1 142  ? 223.755 326.213 257.074 1.00 29.43  ? 142  LEU A CB    1 
ATOM   1098  C CG    . LEU A 1 142  ? 222.966 325.386 258.091 1.00 29.43  ? 142  LEU A CG    1 
ATOM   1099  C CD1   . LEU A 1 142  ? 221.560 325.109 257.585 1.00 29.43  ? 142  LEU A CD1   1 
ATOM   1100  C CD2   . LEU A 1 142  ? 223.692 324.088 258.406 1.00 29.43  ? 142  LEU A CD2   1 
ATOM   1101  N N     . LEU A 1 143  ? 225.669 328.494 255.960 1.00 27.26  ? 143  LEU A N     1 
ATOM   1102  C CA    . LEU A 1 143  ? 226.389 329.089 254.839 1.00 27.26  ? 143  LEU A CA    1 
ATOM   1103  C C     . LEU A 1 143  ? 227.881 329.173 255.127 1.00 27.26  ? 143  LEU A C     1 
ATOM   1104  O O     . LEU A 1 143  ? 228.709 328.798 254.288 1.00 27.26  ? 143  LEU A O     1 
ATOM   1105  C CB    . LEU A 1 143  ? 225.824 330.475 254.535 1.00 27.26  ? 143  LEU A CB    1 
ATOM   1106  C CG    . LEU A 1 143  ? 226.731 331.397 253.718 1.00 27.26  ? 143  LEU A CG    1 
ATOM   1107  C CD1   . LEU A 1 143  ? 226.894 330.888 252.291 1.00 27.26  ? 143  LEU A CD1   1 
ATOM   1108  C CD2   . LEU A 1 143  ? 226.204 332.816 253.737 1.00 27.26  ? 143  LEU A CD2   1 
ATOM   1109  N N     . PHE A 1 144  ? 228.248 329.658 256.315 1.00 28.39  ? 144  PHE A N     1 
ATOM   1110  C CA    . PHE A 1 144  ? 229.666 329.799 256.627 1.00 28.39  ? 144  PHE A CA    1 
ATOM   1111  C C     . PHE A 1 144  ? 230.322 328.441 256.844 1.00 28.39  ? 144  PHE A C     1 
ATOM   1112  O O     . PHE A 1 144  ? 231.502 328.263 256.525 1.00 28.39  ? 144  PHE A O     1 
ATOM   1113  C CB    . PHE A 1 144  ? 229.854 330.709 257.838 1.00 28.39  ? 144  PHE A CB    1 
ATOM   1114  C CG    . PHE A 1 144  ? 229.947 332.165 257.481 1.00 28.39  ? 144  PHE A CG    1 
ATOM   1115  C CD1   . PHE A 1 144  ? 230.937 332.616 256.623 1.00 28.39  ? 144  PHE A CD1   1 
ATOM   1116  C CD2   . PHE A 1 144  ? 229.040 333.078 257.988 1.00 28.39  ? 144  PHE A CD2   1 
ATOM   1117  C CE1   . PHE A 1 144  ? 231.024 333.953 256.283 1.00 28.39  ? 144  PHE A CE1   1 
ATOM   1118  C CE2   . PHE A 1 144  ? 229.123 334.417 257.653 1.00 28.39  ? 144  PHE A CE2   1 
ATOM   1119  C CZ    . PHE A 1 144  ? 230.115 334.854 256.799 1.00 28.39  ? 144  PHE A CZ    1 
ATOM   1120  N N     . LEU A 1 145  ? 229.572 327.464 257.363 1.00 26.66  ? 145  LEU A N     1 
ATOM   1121  C CA    . LEU A 1 145  ? 230.094 326.105 257.440 1.00 26.66  ? 145  LEU A CA    1 
ATOM   1122  C C     . LEU A 1 145  ? 230.416 325.570 256.052 1.00 26.66  ? 145  LEU A C     1 
ATOM   1123  O O     . LEU A 1 145  ? 231.478 324.973 255.839 1.00 26.66  ? 145  LEU A O     1 
ATOM   1124  C CB    . LEU A 1 145  ? 229.086 325.200 258.149 1.00 26.66  ? 145  LEU A CB    1 
ATOM   1125  C CG    . LEU A 1 145  ? 229.191 323.689 257.927 1.00 26.66  ? 145  LEU A CG    1 
ATOM   1126  C CD1   . LEU A 1 145  ? 230.505 323.139 258.458 1.00 26.66  ? 145  LEU A CD1   1 
ATOM   1127  C CD2   . LEU A 1 145  ? 228.012 322.978 258.567 1.00 26.66  ? 145  LEU A CD2   1 
ATOM   1128  N N     . ALA A 1 146  ? 229.516 325.791 255.091 1.00 27.91  ? 146  ALA A N     1 
ATOM   1129  C CA    . ALA A 1 146  ? 229.778 325.369 253.719 1.00 27.91  ? 146  ALA A CA    1 
ATOM   1130  C C     . ALA A 1 146  ? 230.984 326.098 253.137 1.00 27.91  ? 146  ALA A C     1 
ATOM   1131  O O     . ALA A 1 146  ? 231.802 325.495 252.432 1.00 27.91  ? 146  ALA A O     1 
ATOM   1132  C CB    . ALA A 1 146  ? 228.540 325.601 252.853 1.00 27.91  ? 146  ALA A CB    1 
ATOM   1133  N N     . GLN A 1 147  ? 231.104 327.398 253.414 1.00 28.69  ? 147  GLN A N     1 
ATOM   1134  C CA    . GLN A 1 147  ? 232.226 328.169 252.883 1.00 28.69  ? 147  GLN A CA    1 
ATOM   1135  C C     . GLN A 1 147  ? 233.557 327.658 253.426 1.00 28.69  ? 147  GLN A C     1 
ATOM   1136  O O     . GLN A 1 147  ? 234.525 327.497 252.675 1.00 28.69  ? 147  GLN A O     1 
ATOM   1137  C CB    . GLN A 1 147  ? 232.045 329.654 253.204 1.00 28.69  ? 147  GLN A CB    1 
ATOM   1138  C CG    . GLN A 1 147  ? 230.824 330.289 252.557 1.00 28.69  ? 147  GLN A CG    1 
ATOM   1139  C CD    . GLN A 1 147  ? 231.139 330.951 251.231 1.00 28.69  ? 147  GLN A CD    1 
ATOM   1140  O OE1   . GLN A 1 147  ? 232.028 330.514 250.501 1.00 28.69  ? 147  GLN A OE1   1 
ATOM   1141  N NE2   . GLN A 1 147  ? 230.408 332.013 250.912 1.00 28.69  ? 147  GLN A NE2   1 
ATOM   1142  N N     . MET A 1 148  ? 233.624 327.393 254.734 1.00 29.75  ? 148  MET A N     1 
ATOM   1143  C CA    . MET A 1 148  ? 234.864 326.878 255.312 1.00 29.75  ? 148  MET A CA    1 
ATOM   1144  C C     . MET A 1 148  ? 235.148 325.453 254.849 1.00 29.75  ? 148  MET A C     1 
ATOM   1145  O O     . MET A 1 148  ? 236.313 325.075 254.680 1.00 29.75  ? 148  MET A O     1 
ATOM   1146  C CB    . MET A 1 148  ? 234.819 326.952 256.838 1.00 29.75  ? 148  MET A CB    1 
ATOM   1147  C CG    . MET A 1 148  ? 234.405 328.306 257.384 1.00 29.75  ? 148  MET A CG    1 
ATOM   1148  S SD    . MET A 1 148  ? 234.455 328.380 259.183 1.00 29.75  ? 148  MET A SD    1 
ATOM   1149  C CE    . MET A 1 148  ? 234.477 330.151 259.449 1.00 29.75  ? 148  MET A CE    1 
ATOM   1150  N N     . THR A 1 149  ? 234.103 324.645 254.647 1.00 26.26  ? 149  THR A N     1 
ATOM   1151  C CA    . THR A 1 149  ? 234.308 323.305 254.108 1.00 26.26  ? 149  THR A CA    1 
ATOM   1152  C C     . THR A 1 149  ? 234.892 323.367 252.702 1.00 26.26  ? 149  THR A C     1 
ATOM   1153  O O     . THR A 1 149  ? 235.813 322.611 252.368 1.00 26.26  ? 149  THR A O     1 
ATOM   1154  C CB    . THR A 1 149  ? 232.989 322.530 254.112 1.00 26.26  ? 149  THR A CB    1 
ATOM   1155  O OG1   . THR A 1 149  ? 232.612 322.233 255.463 1.00 26.26  ? 149  THR A OG1   1 
ATOM   1156  C CG2   . THR A 1 149  ? 233.125 321.229 253.335 1.00 26.26  ? 149  THR A CG2   1 
ATOM   1157  N N     . ALA A 1 150  ? 234.376 324.272 251.868 1.00 27.60  ? 150  ALA A N     1 
ATOM   1158  C CA    . ALA A 1 150  ? 234.935 324.451 250.532 1.00 27.60  ? 150  ALA A CA    1 
ATOM   1159  C C     . ALA A 1 150  ? 236.346 325.019 250.587 1.00 27.60  ? 150  ALA A C     1 
ATOM   1160  O O     . ALA A 1 150  ? 237.166 324.730 249.708 1.00 27.60  ? 150  ALA A O     1 
ATOM   1161  C CB    . ALA A 1 150  ? 234.028 325.356 249.698 1.00 27.60  ? 150  ALA A CB    1 
ATOM   1162  N N     . SER A 1 151  ? 236.645 325.834 251.603 1.00 28.88  ? 151  SER A N     1 
ATOM   1163  C CA    . SER A 1 151  ? 237.991 326.380 251.745 1.00 28.88  ? 151  SER A CA    1 
ATOM   1164  C C     . SER A 1 151  ? 239.014 325.277 251.988 1.00 28.88  ? 151  SER A C     1 
ATOM   1165  O O     . SER A 1 151  ? 240.119 325.312 251.434 1.00 28.88  ? 151  SER A O     1 
ATOM   1166  C CB    . SER A 1 151  ? 238.024 327.404 252.880 1.00 28.88  ? 151  SER A CB    1 
ATOM   1167  O OG    . SER A 1 151  ? 238.422 326.801 254.099 1.00 28.88  ? 151  SER A OG    1 
ATOM   1168  N N     . GLY A 1 152  ? 238.666 324.291 252.811 1.00 32.94  ? 152  GLY A N     1 
ATOM   1169  C CA    . GLY A 1 152  ? 239.566 323.189 253.088 1.00 32.94  ? 152  GLY A CA    1 
ATOM   1170  C C     . GLY A 1 152  ? 239.518 322.706 254.523 1.00 32.94  ? 152  GLY A C     1 
ATOM   1171  O O     . GLY A 1 152  ? 240.046 321.636 254.840 1.00 32.94  ? 152  GLY A O     1 
ATOM   1172  N N     . LEU A 1 153  ? 238.891 323.485 255.399 1.00 32.27  ? 153  LEU A N     1 
ATOM   1173  C CA    . LEU A 1 153  ? 238.784 323.101 256.800 1.00 32.27  ? 153  LEU A CA    1 
ATOM   1174  C C     . LEU A 1 153  ? 237.851 321.906 256.959 1.00 32.27  ? 153  LEU A C     1 
ATOM   1175  O O     . LEU A 1 153  ? 236.852 321.775 256.246 1.00 32.27  ? 153  LEU A O     1 
ATOM   1176  C CB    . LEU A 1 153  ? 238.280 324.275 257.639 1.00 32.27  ? 153  LEU A CB    1 
ATOM   1177  C CG    . LEU A 1 153  ? 239.336 325.175 258.287 1.00 32.27  ? 153  LEU A CG    1 
ATOM   1178  C CD1   . LEU A 1 153  ? 240.156 325.909 257.236 1.00 32.27  ? 153  LEU A CD1   1 
ATOM   1179  C CD2   . LEU A 1 153  ? 238.685 326.160 259.247 1.00 32.27  ? 153  LEU A CD2   1 
ATOM   1180  N N     . HIS A 1 154  ? 238.185 321.030 257.903 1.00 34.76  ? 154  HIS A N     1 
ATOM   1181  C CA    . HIS A 1 154  ? 237.389 319.845 258.196 1.00 34.76  ? 154  HIS A CA    1 
ATOM   1182  C C     . HIS A 1 154  ? 236.593 320.071 259.474 1.00 34.76  ? 154  HIS A C     1 
ATOM   1183  O O     . HIS A 1 154  ? 237.167 320.392 260.520 1.00 34.76  ? 154  HIS A O     1 
ATOM   1184  C CB    . HIS A 1 154  ? 238.280 318.611 258.338 1.00 34.76  ? 154  HIS A CB    1 
ATOM   1185  C CG    . HIS A 1 154  ? 238.955 318.203 257.065 1.00 34.76  ? 154  HIS A CG    1 
ATOM   1186  N ND1   . HIS A 1 154  ? 238.264 317.979 255.894 1.00 34.76  ? 154  HIS A ND1   1 
ATOM   1187  C CD2   . HIS A 1 154  ? 240.260 317.980 256.780 1.00 34.76  ? 154  HIS A CD2   1 
ATOM   1188  C CE1   . HIS A 1 154  ? 239.114 317.635 254.943 1.00 34.76  ? 154  HIS A CE1   1 
ATOM   1189  N NE2   . HIS A 1 154  ? 240.331 317.628 255.454 1.00 34.76  ? 154  HIS A NE2   1 
ATOM   1190  N N     . ILE A 1 155  ? 235.274 319.903 259.386 1.00 36.08  ? 155  ILE A N     1 
ATOM   1191  C CA    . ILE A 1 155  ? 234.393 320.130 260.525 1.00 36.08  ? 155  ILE A CA    1 
ATOM   1192  C C     . ILE A 1 155  ? 233.542 318.892 260.776 1.00 36.08  ? 155  ILE A C     1 
ATOM   1193  O O     . ILE A 1 155  ? 233.517 318.358 261.891 1.00 36.08  ? 155  ILE A O     1 
ATOM   1194  C CB    . ILE A 1 155  ? 233.518 321.378 260.305 1.00 36.08  ? 155  ILE A CB    1 
ATOM   1195  C CG1   . ILE A 1 155  ? 234.363 322.645 260.464 1.00 36.08  ? 155  ILE A CG1   1 
ATOM   1196  C CG2   . ILE A 1 155  ? 232.345 321.390 261.272 1.00 36.08  ? 155  ILE A CG2   1 
ATOM   1197  C CD1   . ILE A 1 155  ? 233.807 323.854 259.748 1.00 36.08  ? 155  ILE A CD1   1 
ATOM   1198  N N     . ILE A 1 156  ? 232.838 318.426 259.742 1.00 40.52  ? 156  ILE A N     1 
ATOM   1199  C CA    . ILE A 1 156  ? 231.992 317.247 259.883 1.00 40.52  ? 156  ILE A CA    1 
ATOM   1200  C C     . ILE A 1 156  ? 232.863 316.013 260.075 1.00 40.52  ? 156  ILE A C     1 
ATOM   1201  O O     . ILE A 1 156  ? 233.833 315.790 259.338 1.00 40.52  ? 156  ILE A O     1 
ATOM   1202  C CB    . ILE A 1 156  ? 231.072 317.097 258.660 1.00 40.52  ? 156  ILE A CB    1 
ATOM   1203  C CG1   . ILE A 1 156  ? 230.283 318.386 258.424 1.00 40.52  ? 156  ILE A CG1   1 
ATOM   1204  C CG2   . ILE A 1 156  ? 230.126 315.922 258.848 1.00 40.52  ? 156  ILE A CG2   1 
ATOM   1205  C CD1   . ILE A 1 156  ? 229.478 318.841 259.624 1.00 40.52  ? 156  ILE A CD1   1 
ATOM   1206  N N     . HIS A 1 157  ? 232.517 315.198 261.074 1.00 64.40  ? 157  HIS A N     1 
ATOM   1207  C CA    . HIS A 1 157  ? 233.317 314.037 261.436 1.00 64.40  ? 157  HIS A CA    1 
ATOM   1208  C C     . HIS A 1 157  ? 232.572 312.712 261.365 1.00 64.40  ? 157  HIS A C     1 
ATOM   1209  O O     . HIS A 1 157  ? 233.217 311.661 261.461 1.00 64.40  ? 157  HIS A O     1 
ATOM   1210  C CB    . HIS A 1 157  ? 233.887 314.204 262.854 1.00 64.40  ? 157  HIS A CB    1 
ATOM   1211  C CG    . HIS A 1 157  ? 235.026 315.172 262.939 1.00 64.40  ? 157  HIS A CG    1 
ATOM   1212  N ND1   . HIS A 1 157  ? 235.709 315.416 264.111 1.00 64.40  ? 157  HIS A ND1   1 
ATOM   1213  C CD2   . HIS A 1 157  ? 235.601 315.958 261.998 1.00 64.40  ? 157  HIS A CD2   1 
ATOM   1214  C CE1   . HIS A 1 157  ? 236.655 316.311 263.889 1.00 64.40  ? 157  HIS A CE1   1 
ATOM   1215  N NE2   . HIS A 1 157  ? 236.611 316.656 262.614 1.00 64.40  ? 157  HIS A NE2   1 
ATOM   1216  N N     . SER A 1 158  ? 231.250 312.718 261.204 1.00 45.66  ? 158  SER A N     1 
ATOM   1217  C CA    . SER A 1 158  ? 230.489 311.477 261.210 1.00 45.66  ? 158  SER A CA    1 
ATOM   1218  C C     . SER A 1 158  ? 229.273 311.614 260.305 1.00 45.66  ? 158  SER A C     1 
ATOM   1219  O O     . SER A 1 158  ? 228.839 312.721 259.975 1.00 45.66  ? 158  SER A O     1 
ATOM   1220  C CB    . SER A 1 158  ? 230.056 311.091 262.629 1.00 45.66  ? 158  SER A CB    1 
ATOM   1221  O OG    . SER A 1 158  ? 228.708 311.455 262.868 1.00 45.66  ? 158  SER A OG    1 
ATOM   1222  N N     . LEU A 1 159  ? 228.728 310.461 259.906 1.00 40.93  ? 159  LEU A N     1 
ATOM   1223  C CA    . LEU A 1 159  ? 227.538 310.452 259.062 1.00 40.93  ? 159  LEU A CA    1 
ATOM   1224  C C     . LEU A 1 159  ? 226.307 310.937 259.818 1.00 40.93  ? 159  LEU A C     1 
ATOM   1225  O O     . LEU A 1 159  ? 225.372 311.465 259.204 1.00 40.93  ? 159  LEU A O     1 
ATOM   1226  C CB    . LEU A 1 159  ? 227.299 309.049 258.504 1.00 40.93  ? 159  LEU A CB    1 
ATOM   1227  C CG    . LEU A 1 159  ? 227.865 308.754 257.113 1.00 40.93  ? 159  LEU A CG    1 
ATOM   1228  C CD1   . LEU A 1 159  ? 229.386 308.749 257.132 1.00 40.93  ? 159  LEU A CD1   1 
ATOM   1229  C CD2   . LEU A 1 159  ? 227.327 307.433 256.584 1.00 40.93  ? 159  LEU A CD2   1 
ATOM   1230  N N     . ASP A 1 160  ? 226.283 310.758 261.141 1.00 44.10  ? 160  ASP A N     1 
ATOM   1231  C CA    . ASP A 1 160  ? 225.185 311.296 261.937 1.00 44.10  ? 160  ASP A CA    1 
ATOM   1232  C C     . ASP A 1 160  ? 225.147 312.816 261.853 1.00 44.10  ? 160  ASP A C     1 
ATOM   1233  O O     . ASP A 1 160  ? 224.069 313.418 261.790 1.00 44.10  ? 160  ASP A O     1 
ATOM   1234  C CB    . ASP A 1 160  ? 225.315 310.840 263.390 1.00 44.10  ? 160  ASP A CB    1 
ATOM   1235  C CG    . ASP A 1 160  ? 225.376 309.331 263.524 1.00 44.10  ? 160  ASP A CG    1 
ATOM   1236  O OD1   . ASP A 1 160  ? 225.342 308.639 262.485 1.00 44.10  ? 160  ASP A OD1   1 
ATOM   1237  O OD2   . ASP A 1 160  ? 225.460 308.837 264.668 1.00 44.10  ? 160  ASP A OD2   1 
ATOM   1238  N N     . GLU A 1 161  ? 226.320 313.454 261.849 1.00 43.80  ? 161  GLU A N     1 
ATOM   1239  C CA    . GLU A 1 161  ? 226.377 314.898 261.658 1.00 43.80  ? 161  GLU A CA    1 
ATOM   1240  C C     . GLU A 1 161  ? 225.854 315.291 260.282 1.00 43.80  ? 161  GLU A C     1 
ATOM   1241  O O     . GLU A 1 161  ? 225.182 316.318 260.137 1.00 43.80  ? 161  GLU A O     1 
ATOM   1242  C CB    . GLU A 1 161  ? 227.807 315.397 261.856 1.00 43.80  ? 161  GLU A CB    1 
ATOM   1243  C CG    . GLU A 1 161  ? 228.215 315.536 263.314 1.00 43.80  ? 161  GLU A CG    1 
ATOM   1244  C CD    . GLU A 1 161  ? 229.718 315.504 263.504 1.00 43.80  ? 161  GLU A CD    1 
ATOM   1245  O OE1   . GLU A 1 161  ? 230.447 315.537 262.491 1.00 43.80  ? 161  GLU A OE1   1 
ATOM   1246  O OE2   . GLU A 1 161  ? 230.169 315.445 264.667 1.00 43.80  ? 161  GLU A OE2   1 
ATOM   1247  N N     . VAL A 1 162  ? 226.151 314.485 259.260 1.00 35.45  ? 162  VAL A N     1 
ATOM   1248  C CA    . VAL A 1 162  ? 225.632 314.756 257.921 1.00 35.45  ? 162  VAL A CA    1 
ATOM   1249  C C     . VAL A 1 162  ? 224.110 314.670 257.911 1.00 35.45  ? 162  VAL A C     1 
ATOM   1250  O O     . VAL A 1 162  ? 223.427 315.515 257.317 1.00 35.45  ? 162  VAL A O     1 
ATOM   1251  C CB    . VAL A 1 162  ? 226.261 313.790 256.899 1.00 35.45  ? 162  VAL A CB    1 
ATOM   1252  C CG1   . VAL A 1 162  ? 225.569 313.912 255.550 1.00 35.45  ? 162  VAL A CG1   1 
ATOM   1253  C CG2   . VAL A 1 162  ? 227.752 314.054 256.765 1.00 35.45  ? 162  VAL A CG2   1 
ATOM   1254  N N     . ASN A 1 163  ? 223.557 313.646 258.566 1.00 35.32  ? 163  ASN A N     1 
ATOM   1255  C CA    . ASN A 1 163  ? 222.105 313.513 258.641 1.00 35.32  ? 163  ASN A CA    1 
ATOM   1256  C C     . ASN A 1 163  ? 221.481 314.683 259.392 1.00 35.32  ? 163  ASN A C     1 
ATOM   1257  O O     . ASN A 1 163  ? 220.425 315.193 258.999 1.00 35.32  ? 163  ASN A O     1 
ATOM   1258  C CB    . ASN A 1 163  ? 221.733 312.187 259.305 1.00 35.32  ? 163  ASN A CB    1 
ATOM   1259  C CG    . ASN A 1 163  ? 221.706 311.031 258.325 1.00 35.32  ? 163  ASN A CG    1 
ATOM   1260  O OD1   . ASN A 1 163  ? 221.166 311.147 257.225 1.00 35.32  ? 163  ASN A OD1   1 
ATOM   1261  N ND2   . ASN A 1 163  ? 222.288 309.905 258.721 1.00 35.32  ? 163  ASN A ND2   1 
ATOM   1262  N N     . PHE A 1 164  ? 222.120 315.120 260.479 1.00 30.69  ? 164  PHE A N     1 
ATOM   1263  C CA    . PHE A 1 164  ? 221.607 316.262 261.229 1.00 30.69  ? 164  PHE A CA    1 
ATOM   1264  C C     . PHE A 1 164  ? 221.659 317.540 260.398 1.00 30.69  ? 164  PHE A C     1 
ATOM   1265  O O     . PHE A 1 164  ? 220.748 318.371 260.468 1.00 30.69  ? 164  PHE A O     1 
ATOM   1266  C CB    . PHE A 1 164  ? 222.391 316.435 262.528 1.00 30.69  ? 164  PHE A CB    1 
ATOM   1267  C CG    . PHE A 1 164  ? 221.891 317.558 263.388 1.00 30.69  ? 164  PHE A CG    1 
ATOM   1268  C CD1   . PHE A 1 164  ? 220.605 317.534 263.900 1.00 30.69  ? 164  PHE A CD1   1 
ATOM   1269  C CD2   . PHE A 1 164  ? 222.704 318.640 263.678 1.00 30.69  ? 164  PHE A CD2   1 
ATOM   1270  C CE1   . PHE A 1 164  ? 220.140 318.567 264.690 1.00 30.69  ? 164  PHE A CE1   1 
ATOM   1271  C CE2   . PHE A 1 164  ? 222.245 319.674 264.469 1.00 30.69  ? 164  PHE A CE2   1 
ATOM   1272  C CZ    . PHE A 1 164  ? 220.961 319.639 264.974 1.00 30.69  ? 164  PHE A CZ    1 
ATOM   1273  N N     . ILE A 1 165  ? 222.723 317.718 259.612 1.00 30.30  ? 165  ILE A N     1 
ATOM   1274  C CA    . ILE A 1 165  ? 222.823 318.887 258.742 1.00 30.30  ? 165  ILE A CA    1 
ATOM   1275  C C     . ILE A 1 165  ? 221.737 318.849 257.674 1.00 30.30  ? 165  ILE A C     1 
ATOM   1276  O O     . ILE A 1 165  ? 221.133 319.877 257.342 1.00 30.30  ? 165  ILE A O     1 
ATOM   1277  C CB    . ILE A 1 165  ? 224.232 318.975 258.126 1.00 30.30  ? 165  ILE A CB    1 
ATOM   1278  C CG1   . ILE A 1 165  ? 225.251 319.375 259.194 1.00 30.30  ? 165  ILE A CG1   1 
ATOM   1279  C CG2   . ILE A 1 165  ? 224.257 319.957 256.962 1.00 30.30  ? 165  ILE A CG2   1 
ATOM   1280  C CD1   . ILE A 1 165  ? 225.225 320.845 259.544 1.00 30.30  ? 165  ILE A CD1   1 
ATOM   1281  N N     . GLN A 1 166  ? 221.472 317.665 257.119 1.00 33.37  ? 166  GLN A N     1 
ATOM   1282  C CA    . GLN A 1 166  ? 220.387 317.529 256.151 1.00 33.37  ? 166  GLN A CA    1 
ATOM   1283  C C     . GLN A 1 166  ? 219.040 317.863 256.785 1.00 33.37  ? 166  GLN A C     1 
ATOM   1284  O O     . GLN A 1 166  ? 218.202 318.536 256.171 1.00 33.37  ? 166  GLN A O     1 
ATOM   1285  C CB    . GLN A 1 166  ? 220.378 316.113 255.576 1.00 33.37  ? 166  GLN A CB    1 
ATOM   1286  C CG    . GLN A 1 166  ? 219.558 315.957 254.309 1.00 33.37  ? 166  GLN A CG    1 
ATOM   1287  C CD    . GLN A 1 166  ? 220.391 316.112 253.052 1.00 33.37  ? 166  GLN A CD    1 
ATOM   1288  O OE1   . GLN A 1 166  ? 220.129 316.984 252.224 1.00 33.37  ? 166  GLN A OE1   1 
ATOM   1289  N NE2   . GLN A 1 166  ? 221.403 315.265 252.905 1.00 33.37  ? 166  GLN A NE2   1 
ATOM   1290  N N     . ASN A 1 167  ? 218.819 317.404 258.019 1.00 32.07  ? 167  ASN A N     1 
ATOM   1291  C CA    . ASN A 1 167  ? 217.581 317.726 258.722 1.00 32.07  ? 167  ASN A CA    1 
ATOM   1292  C C     . ASN A 1 167  ? 217.463 319.223 258.981 1.00 32.07  ? 167  ASN A C     1 
ATOM   1293  O O     . ASN A 1 167  ? 216.373 319.795 258.875 1.00 32.07  ? 167  ASN A O     1 
ATOM   1294  C CB    . ASN A 1 167  ? 217.505 316.943 260.033 1.00 32.07  ? 167  ASN A CB    1 
ATOM   1295  C CG    . ASN A 1 167  ? 216.696 315.667 259.903 1.00 32.07  ? 167  ASN A CG    1 
ATOM   1296  O OD1   . ASN A 1 167  ? 215.483 315.664 260.115 1.00 32.07  ? 167  ASN A OD1   1 
ATOM   1297  N ND2   . ASN A 1 167  ? 217.365 314.574 259.554 1.00 32.07  ? 167  ASN A ND2   1 
ATOM   1298  N N     . LEU A 1 168  ? 218.575 319.875 259.331 1.00 31.40  ? 168  LEU A N     1 
ATOM   1299  C CA    . LEU A 1 168  ? 218.556 321.320 259.543 1.00 31.40  ? 168  LEU A CA    1 
ATOM   1300  C C     . LEU A 1 168  ? 218.253 322.063 258.247 1.00 31.40  ? 168  LEU A C     1 
ATOM   1301  O O     . LEU A 1 168  ? 217.540 323.074 258.252 1.00 31.40  ? 168  LEU A O     1 
ATOM   1302  C CB    . LEU A 1 168  ? 219.892 321.785 260.124 1.00 31.40  ? 168  LEU A CB    1 
ATOM   1303  C CG    . LEU A 1 168  ? 219.969 321.936 261.645 1.00 31.40  ? 168  LEU A CG    1 
ATOM   1304  C CD1   . LEU A 1 168  ? 221.412 322.120 262.086 1.00 31.40  ? 168  LEU A CD1   1 
ATOM   1305  C CD2   . LEU A 1 168  ? 219.105 323.088 262.121 1.00 31.40  ? 168  LEU A CD2   1 
ATOM   1306  N N     . VAL A 1 169  ? 218.802 321.585 257.129 1.00 30.28  ? 169  VAL A N     1 
ATOM   1307  C CA    . VAL A 1 169  ? 218.502 322.181 255.829 1.00 30.28  ? 169  VAL A CA    1 
ATOM   1308  C C     . VAL A 1 169  ? 217.019 322.034 255.512 1.00 30.28  ? 169  VAL A C     1 
ATOM   1309  O O     . VAL A 1 169  ? 216.373 322.971 255.025 1.00 30.28  ? 169  VAL A O     1 
ATOM   1310  C CB    . VAL A 1 169  ? 219.387 321.549 254.738 1.00 30.28  ? 169  VAL A CB    1 
ATOM   1311  C CG1   . VAL A 1 169  ? 218.795 321.786 253.357 1.00 30.28  ? 169  VAL A CG1   1 
ATOM   1312  C CG2   . VAL A 1 169  ? 220.806 322.097 254.821 1.00 30.28  ? 169  VAL A CG2   1 
ATOM   1313  N N     . PHE A 1 170  ? 216.458 320.856 255.790 1.00 33.58  ? 170  PHE A N     1 
ATOM   1314  C CA    . PHE A 1 170  ? 215.024 320.646 255.603 1.00 33.58  ? 170  PHE A CA    1 
ATOM   1315  C C     . PHE A 1 170  ? 214.212 321.584 256.486 1.00 33.58  ? 170  PHE A C     1 
ATOM   1316  O O     . PHE A 1 170  ? 213.177 322.112 256.063 1.00 33.58  ? 170  PHE A O     1 
ATOM   1317  C CB    . PHE A 1 170  ? 214.666 319.189 255.903 1.00 33.58  ? 170  PHE A CB    1 
ATOM   1318  C CG    . PHE A 1 170  ? 215.235 318.207 254.922 1.00 33.58  ? 170  PHE A CG    1 
ATOM   1319  C CD1   . PHE A 1 170  ? 215.987 318.637 253.840 1.00 33.58  ? 170  PHE A CD1   1 
ATOM   1320  C CD2   . PHE A 1 170  ? 215.039 316.846 255.097 1.00 33.58  ? 170  PHE A CD2   1 
ATOM   1321  C CE1   . PHE A 1 170  ? 216.512 317.736 252.953 1.00 33.58  ? 170  PHE A CE1   1 
ATOM   1322  C CE2   . PHE A 1 170  ? 215.569 315.942 254.209 1.00 33.58  ? 170  PHE A CE2   1 
ATOM   1323  C CZ    . PHE A 1 170  ? 216.303 316.382 253.134 1.00 33.58  ? 170  PHE A CZ    1 
ATOM   1324  N N     . TYR A 1 171  ? 214.664 321.792 257.722 1.00 34.06  ? 171  TYR A N     1 
ATOM   1325  C CA    . TYR A 1 171  ? 213.949 322.658 258.651 1.00 34.06  ? 171  TYR A CA    1 
ATOM   1326  C C     . TYR A 1 171  ? 213.985 324.114 258.198 1.00 34.06  ? 171  TYR A C     1 
ATOM   1327  O O     . TYR A 1 171  ? 212.989 324.834 258.328 1.00 34.06  ? 171  TYR A O     1 
ATOM   1328  C CB    . TYR A 1 171  ? 214.537 322.487 260.054 1.00 34.06  ? 171  TYR A CB    1 
ATOM   1329  C CG    . TYR A 1 171  ? 214.676 323.752 260.869 1.00 34.06  ? 171  TYR A CG    1 
ATOM   1330  C CD1   . TYR A 1 171  ? 213.573 324.344 261.465 1.00 34.06  ? 171  TYR A CD1   1 
ATOM   1331  C CD2   . TYR A 1 171  ? 215.919 324.334 261.071 1.00 34.06  ? 171  TYR A CD2   1 
ATOM   1332  C CE1   . TYR A 1 171  ? 213.698 325.493 262.223 1.00 34.06  ? 171  TYR A CE1   1 
ATOM   1333  C CE2   . TYR A 1 171  ? 216.056 325.482 261.827 1.00 34.06  ? 171  TYR A CE2   1 
ATOM   1334  C CZ    . TYR A 1 171  ? 214.944 326.058 262.401 1.00 34.06  ? 171  TYR A CZ    1 
ATOM   1335  O OH    . TYR A 1 171  ? 215.082 327.202 263.154 1.00 34.06  ? 171  TYR A OH    1 
ATOM   1336  N N     . ILE A 1 172  ? 215.121 324.566 257.656 1.00 34.16  ? 172  ILE A N     1 
ATOM   1337  C CA    . ILE A 1 172  ? 215.227 325.955 257.205 1.00 34.16  ? 172  ILE A CA    1 
ATOM   1338  C C     . ILE A 1 172  ? 214.656 326.179 255.814 1.00 34.16  ? 172  ILE A C     1 
ATOM   1339  O O     . ILE A 1 172  ? 214.436 327.335 255.431 1.00 34.16  ? 172  ILE A O     1 
ATOM   1340  C CB    . ILE A 1 172  ? 216.683 326.461 257.203 1.00 34.16  ? 172  ILE A CB    1 
ATOM   1341  C CG1   . ILE A 1 172  ? 217.536 325.660 256.218 1.00 34.16  ? 172  ILE A CG1   1 
ATOM   1342  C CG2   . ILE A 1 172  ? 217.273 326.402 258.604 1.00 34.16  ? 172  ILE A CG2   1 
ATOM   1343  C CD1   . ILE A 1 172  ? 218.693 326.450 255.641 1.00 34.16  ? 172  ILE A CD1   1 
ATOM   1344  N N     . GLU A 1 173  ? 214.411 325.116 255.043 1.00 44.97  ? 173  GLU A N     1 
ATOM   1345  C CA    . GLU A 1 173  ? 213.870 325.280 253.697 1.00 44.97  ? 173  GLU A CA    1 
ATOM   1346  C C     . GLU A 1 173  ? 212.465 325.870 253.679 1.00 44.97  ? 173  GLU A C     1 
ATOM   1347  O O     . GLU A 1 173  ? 212.035 326.364 252.630 1.00 44.97  ? 173  GLU A O     1 
ATOM   1348  C CB    . GLU A 1 173  ? 213.875 323.935 252.962 1.00 44.97  ? 173  GLU A CB    1 
ATOM   1349  C CG    . GLU A 1 173  ? 212.543 323.197 252.987 1.00 44.97  ? 173  GLU A CG    1 
ATOM   1350  C CD    . GLU A 1 173  ? 212.499 322.041 252.007 1.00 44.97  ? 173  GLU A CD    1 
ATOM   1351  O OE1   . GLU A 1 173  ? 213.390 321.965 251.136 1.00 44.97  ? 173  GLU A OE1   1 
ATOM   1352  O OE2   . GLU A 1 173  ? 211.574 321.207 252.110 1.00 44.97  ? 173  GLU A OE2   1 
ATOM   1353  N N     . ALA A 1 174  ? 211.744 325.842 254.801 1.00 44.52  ? 174  ALA A N     1 
ATOM   1354  C CA    . ALA A 1 174  ? 210.396 326.391 254.882 1.00 44.52  ? 174  ALA A CA    1 
ATOM   1355  C C     . ALA A 1 174  ? 210.386 327.823 255.407 1.00 44.52  ? 174  ALA A C     1 
ATOM   1356  O O     . ALA A 1 174  ? 209.413 328.248 256.039 1.00 44.52  ? 174  ALA A O     1 
ATOM   1357  C CB    . ALA A 1 174  ? 209.512 325.500 255.754 1.00 44.52  ? 174  ALA A CB    1 
ATOM   1358  N N     . ALA A 1 175  ? 211.456 328.577 255.156 1.00 47.41  ? 175  ALA A N     1 
ATOM   1359  C CA    . ALA A 1 175  ? 211.561 329.943 255.648 1.00 47.41  ? 175  ALA A CA    1 
ATOM   1360  C C     . ALA A 1 175  ? 210.737 330.939 254.843 1.00 47.41  ? 175  ALA A C     1 
ATOM   1361  O O     . ALA A 1 175  ? 210.463 332.035 255.344 1.00 47.41  ? 175  ALA A O     1 
ATOM   1362  C CB    . ALA A 1 175  ? 213.026 330.386 255.655 1.00 47.41  ? 175  ALA A CB    1 
ATOM   1363  N N     . TYR A 1 176  ? 210.329 330.590 253.623 1.00 54.51  ? 176  TYR A N     1 
ATOM   1364  C CA    . TYR A 1 176  ? 209.631 331.531 252.756 1.00 54.51  ? 176  TYR A CA    1 
ATOM   1365  C C     . TYR A 1 176  ? 208.146 331.657 253.072 1.00 54.51  ? 176  TYR A C     1 
ATOM   1366  O O     . TYR A 1 176  ? 207.483 332.528 252.499 1.00 54.51  ? 176  TYR A O     1 
ATOM   1367  C CB    . TYR A 1 176  ? 209.808 331.126 251.290 1.00 54.51  ? 176  TYR A CB    1 
ATOM   1368  C CG    . TYR A 1 176  ? 208.897 330.004 250.846 1.00 54.51  ? 176  TYR A CG    1 
ATOM   1369  C CD1   . TYR A 1 176  ? 209.150 328.690 251.216 1.00 54.51  ? 176  TYR A CD1   1 
ATOM   1370  C CD2   . TYR A 1 176  ? 207.784 330.259 250.054 1.00 54.51  ? 176  TYR A CD2   1 
ATOM   1371  C CE1   . TYR A 1 176  ? 208.320 327.661 250.813 1.00 54.51  ? 176  TYR A CE1   1 
ATOM   1372  C CE2   . TYR A 1 176  ? 206.949 329.237 249.647 1.00 54.51  ? 176  TYR A CE2   1 
ATOM   1373  C CZ    . TYR A 1 176  ? 207.222 327.940 250.028 1.00 54.51  ? 176  TYR A CZ    1 
ATOM   1374  O OH    . TYR A 1 176  ? 206.392 326.920 249.623 1.00 54.51  ? 176  TYR A OH    1 
ATOM   1375  N N     . LYS A 1 177  ? 207.606 330.818 253.961 1.00 52.83  ? 177  LYS A N     1 
ATOM   1376  C CA    . LYS A 1 177  ? 206.185 330.871 254.282 1.00 52.83  ? 177  LYS A CA    1 
ATOM   1377  C C     . LYS A 1 177  ? 205.944 330.794 255.786 1.00 52.83  ? 177  LYS A C     1 
ATOM   1378  O O     . LYS A 1 177  ? 204.907 330.286 256.227 1.00 52.83  ? 177  LYS A O     1 
ATOM   1379  C CB    . LYS A 1 177  ? 205.419 329.754 253.566 1.00 52.83  ? 177  LYS A CB    1 
ATOM   1380  C CG    . LYS A 1 177  ? 205.896 328.349 253.900 1.00 52.83  ? 177  LYS A CG    1 
ATOM   1381  C CD    . LYS A 1 177  ? 205.222 327.317 253.009 1.00 52.83  ? 177  LYS A CD    1 
ATOM   1382  C CE    . LYS A 1 177  ? 205.945 325.982 253.061 1.00 52.83  ? 177  LYS A CE    1 
ATOM   1383  N NZ    . LYS A 1 177  ? 204.993 324.840 253.134 1.00 52.83  ? 177  LYS A NZ    1 
ATOM   1384  N N     . THR A 1 178  ? 206.882 331.298 256.585 1.00 49.12  ? 178  THR A N     1 
ATOM   1385  C CA    . THR A 1 178  ? 206.749 331.313 258.033 1.00 49.12  ? 178  THR A CA    1 
ATOM   1386  C C     . THR A 1 178  ? 207.173 332.671 258.573 1.00 49.12  ? 178  THR A C     1 
ATOM   1387  O O     . THR A 1 178  ? 207.948 333.396 257.942 1.00 49.12  ? 178  THR A O     1 
ATOM   1388  C CB    . THR A 1 178  ? 207.581 330.199 258.692 1.00 49.12  ? 178  THR A CB    1 
ATOM   1389  O OG1   . THR A 1 178  ? 207.245 330.107 260.083 1.00 49.12  ? 178  THR A OG1   1 
ATOM   1390  C CG2   . THR A 1 178  ? 209.069 330.480 258.549 1.00 49.12  ? 178  THR A CG2   1 
ATOM   1391  N N     . ALA A 1 179  ? 206.646 333.014 259.745 1.00 49.54  ? 179  ALA A N     1 
ATOM   1392  C CA    . ALA A 1 179  ? 206.931 334.285 260.397 1.00 49.54  ? 179  ALA A CA    1 
ATOM   1393  C C     . ALA A 1 179  ? 207.863 334.057 261.579 1.00 49.54  ? 179  ALA A C     1 
ATOM   1394  O O     . ALA A 1 179  ? 207.621 333.170 262.404 1.00 49.54  ? 179  ALA A O     1 
ATOM   1395  C CB    . ALA A 1 179  ? 205.641 334.961 260.862 1.00 49.54  ? 179  ALA A CB    1 
ATOM   1396  N N     . ASP A 1 180  ? 208.922 334.859 261.657 1.00 51.81  ? 180  ASP A N     1 
ATOM   1397  C CA    . ASP A 1 180  ? 209.914 334.755 262.716 1.00 51.81  ? 180  ASP A CA    1 
ATOM   1398  C C     . ASP A 1 180  ? 210.110 336.119 263.365 1.00 51.81  ? 180  ASP A C     1 
ATOM   1399  O O     . ASP A 1 180  ? 209.570 337.133 262.914 1.00 51.81  ? 180  ASP A O     1 
ATOM   1400  C CB    . ASP A 1 180  ? 211.251 334.221 262.182 1.00 51.81  ? 180  ASP A CB    1 
ATOM   1401  C CG    . ASP A 1 180  ? 211.622 334.818 260.839 1.00 51.81  ? 180  ASP A CG    1 
ATOM   1402  O OD1   . ASP A 1 180  ? 210.704 335.158 260.063 1.00 51.81  ? 180  ASP A OD1   1 
ATOM   1403  O OD2   . ASP A 1 180  ? 212.832 334.947 260.559 1.00 51.81  ? 180  ASP A OD2   1 
ATOM   1404  N N     . PHE A 1 181  ? 210.896 336.135 264.442 1.00 50.85  ? 181  PHE A N     1 
ATOM   1405  C CA    . PHE A 1 181  ? 211.151 337.363 265.184 1.00 50.85  ? 181  PHE A CA    1 
ATOM   1406  C C     . PHE A 1 181  ? 212.214 338.243 264.539 1.00 50.85  ? 181  PHE A C     1 
ATOM   1407  O O     . PHE A 1 181  ? 212.376 339.394 264.958 1.00 50.85  ? 181  PHE A O     1 
ATOM   1408  C CB    . PHE A 1 181  ? 211.559 337.032 266.621 1.00 50.85  ? 181  PHE A CB    1 
ATOM   1409  C CG    . PHE A 1 181  ? 210.454 336.426 267.439 1.00 50.85  ? 181  PHE A CG    1 
ATOM   1410  C CD1   . PHE A 1 181  ? 209.551 337.233 268.112 1.00 50.85  ? 181  PHE A CD1   1 
ATOM   1411  C CD2   . PHE A 1 181  ? 210.317 335.051 267.533 1.00 50.85  ? 181  PHE A CD2   1 
ATOM   1412  C CE1   . PHE A 1 181  ? 208.532 336.679 268.864 1.00 50.85  ? 181  PHE A CE1   1 
ATOM   1413  C CE2   . PHE A 1 181  ? 209.300 334.492 268.284 1.00 50.85  ? 181  PHE A CE2   1 
ATOM   1414  C CZ    . PHE A 1 181  ? 208.407 335.307 268.950 1.00 50.85  ? 181  PHE A CZ    1 
ATOM   1415  N N     . GLY A 1 182  ? 212.936 337.738 263.544 1.00 45.78  ? 182  GLY A N     1 
ATOM   1416  C CA    . GLY A 1 182  ? 213.917 338.539 262.846 1.00 45.78  ? 182  GLY A CA    1 
ATOM   1417  C C     . GLY A 1 182  ? 215.245 338.636 263.574 1.00 45.78  ? 182  GLY A C     1 
ATOM   1418  O O     . GLY A 1 182  ? 215.500 337.980 264.588 1.00 45.78  ? 182  GLY A O     1 
ATOM   1419  N N     . ILE A 1 183  ? 216.113 339.485 263.019 1.00 43.12  ? 183  ILE A N     1 
ATOM   1420  C CA    . ILE A 1 183  ? 217.451 339.665 263.573 1.00 43.12  ? 183  ILE A CA    1 
ATOM   1421  C C     . ILE A 1 183  ? 217.383 340.312 264.950 1.00 43.12  ? 183  ILE A C     1 
ATOM   1422  O O     . ILE A 1 183  ? 218.091 339.906 265.879 1.00 43.12  ? 183  ILE A O     1 
ATOM   1423  C CB    . ILE A 1 183  ? 218.322 340.489 262.606 1.00 43.12  ? 183  ILE A CB    1 
ATOM   1424  C CG1   . ILE A 1 183  ? 218.190 339.959 261.177 1.00 43.12  ? 183  ILE A CG1   1 
ATOM   1425  C CG2   . ILE A 1 183  ? 219.776 340.472 263.052 1.00 43.12  ? 183  ILE A CG2   1 
ATOM   1426  C CD1   . ILE A 1 183  ? 217.279 340.788 260.295 1.00 43.12  ? 183  ILE A CD1   1 
ATOM   1427  N N     . TRP A 1 184  ? 216.532 341.326 265.107 1.00 41.00  ? 184  TRP A N     1 
ATOM   1428  C CA    . TRP A 1 184  ? 216.442 342.066 266.358 1.00 41.00  ? 184  TRP A CA    1 
ATOM   1429  C C     . TRP A 1 184  ? 215.672 341.321 267.440 1.00 41.00  ? 184  TRP A C     1 
ATOM   1430  O O     . TRP A 1 184  ? 215.613 341.809 268.575 1.00 41.00  ? 184  TRP A O     1 
ATOM   1431  C CB    . TRP A 1 184  ? 215.793 343.432 266.111 1.00 41.00  ? 184  TRP A CB    1 
ATOM   1432  C CG    . TRP A 1 184  ? 216.224 344.085 264.828 1.00 41.00  ? 184  TRP A CG    1 
ATOM   1433  C CD1   . TRP A 1 184  ? 215.411 344.553 263.837 1.00 41.00  ? 184  TRP A CD1   1 
ATOM   1434  C CD2   . TRP A 1 184  ? 217.568 344.354 264.403 1.00 41.00  ? 184  TRP A CD2   1 
ATOM   1435  N NE1   . TRP A 1 184  ? 216.163 345.089 262.820 1.00 41.00  ? 184  TRP A NE1   1 
ATOM   1436  C CE2   . TRP A 1 184  ? 217.490 344.980 263.143 1.00 41.00  ? 184  TRP A CE2   1 
ATOM   1437  C CE3   . TRP A 1 184  ? 218.829 344.124 264.965 1.00 41.00  ? 184  TRP A CE3   1 
ATOM   1438  C CZ2   . TRP A 1 184  ? 218.623 345.378 262.436 1.00 41.00  ? 184  TRP A CZ2   1 
ATOM   1439  C CZ3   . TRP A 1 184  ? 219.952 344.520 264.260 1.00 41.00  ? 184  TRP A CZ3   1 
ATOM   1440  C CH2   . TRP A 1 184  ? 219.841 345.140 263.010 1.00 41.00  ? 184  TRP A CH2   1 
ATOM   1441  N N     . GLU A 1 185  ? 215.087 340.165 267.119 1.00 49.62  ? 185  GLU A N     1 
ATOM   1442  C CA    . GLU A 1 185  ? 214.324 339.359 268.075 1.00 49.62  ? 185  GLU A CA    1 
ATOM   1443  C C     . GLU A 1 185  ? 213.174 340.149 268.691 1.00 49.62  ? 185  GLU A C     1 
ATOM   1444  O O     . GLU A 1 185  ? 212.826 339.953 269.858 1.00 49.62  ? 185  GLU A O     1 
ATOM   1445  C CB    . GLU A 1 185  ? 215.228 338.788 269.174 1.00 49.62  ? 185  GLU A CB    1 
ATOM   1446  C CG    . GLU A 1 185  ? 216.592 338.321 268.690 1.00 49.62  ? 185  GLU A CG    1 
ATOM   1447  C CD    . GLU A 1 185  ? 217.369 337.583 269.762 1.00 49.62  ? 185  GLU A CD    1 
ATOM   1448  O OE1   . GLU A 1 185  ? 217.073 336.393 270.002 1.00 49.62  ? 185  GLU A OE1   1 
ATOM   1449  O OE2   . GLU A 1 185  ? 218.278 338.192 270.365 1.00 49.62  ? 185  GLU A OE2   1 
ATOM   1450  N N     . ARG A 1 186  ? 212.572 341.051 267.909 1.00 56.53  ? 186  ARG A N     1 
ATOM   1451  C CA    . ARG A 1 186  ? 211.476 341.872 268.409 1.00 56.53  ? 186  ARG A CA    1 
ATOM   1452  C C     . ARG A 1 186  ? 210.312 341.945 267.426 1.00 56.53  ? 186  ARG A C     1 
ATOM   1453  O O     . ARG A 1 186  ? 209.375 342.722 267.648 1.00 56.53  ? 186  ARG A O     1 
ATOM   1454  C CB    . ARG A 1 186  ? 211.965 343.289 268.736 1.00 56.53  ? 186  ARG A CB    1 
ATOM   1455  C CG    . ARG A 1 186  ? 212.970 343.350 269.876 1.00 56.53  ? 186  ARG A CG    1 
ATOM   1456  C CD    . ARG A 1 186  ? 213.440 344.772 270.133 1.00 56.53  ? 186  ARG A CD    1 
ATOM   1457  N NE    . ARG A 1 186  ? 213.824 344.972 271.526 1.00 56.53  ? 186  ARG A NE    1 
ATOM   1458  C CZ    . ARG A 1 186  ? 214.181 346.138 272.045 1.00 56.53  ? 186  ARG A CZ    1 
ATOM   1459  N NH1   . ARG A 1 186  ? 214.216 347.240 271.313 1.00 56.53  ? 186  ARG A NH1   1 
ATOM   1460  N NH2   . ARG A 1 186  ? 214.512 346.202 273.332 1.00 56.53  ? 186  ARG A NH2   1 
ATOM   1461  N N     . GLY A 1 187  ? 210.340 341.153 266.357 1.00 56.41  ? 187  GLY A N     1 
ATOM   1462  C CA    . GLY A 1 187  ? 209.263 341.198 265.381 1.00 56.41  ? 187  GLY A CA    1 
ATOM   1463  C C     . GLY A 1 187  ? 209.192 342.550 264.700 1.00 56.41  ? 187  GLY A C     1 
ATOM   1464  O O     . GLY A 1 187  ? 210.189 343.068 264.185 1.00 56.41  ? 187  GLY A O     1 
ATOM   1465  N N     . ASP A 1 188  ? 207.998 343.136 264.696 1.00 69.07  ? 188  ASP A N     1 
ATOM   1466  C CA    . ASP A 1 188  ? 207.781 344.443 264.092 1.00 69.07  ? 188  ASP A CA    1 
ATOM   1467  C C     . ASP A 1 188  ? 208.237 345.533 265.063 1.00 69.07  ? 188  ASP A C     1 
ATOM   1468  O O     . ASP A 1 188  ? 208.921 345.270 266.056 1.00 69.07  ? 188  ASP A O     1 
ATOM   1469  C CB    . ASP A 1 188  ? 206.319 344.602 263.684 1.00 69.07  ? 188  ASP A CB    1 
ATOM   1470  C CG    . ASP A 1 188  ? 205.374 344.553 264.867 1.00 69.07  ? 188  ASP A CG    1 
ATOM   1471  O OD1   . ASP A 1 188  ? 205.105 343.441 265.368 1.00 69.07  ? 188  ASP A OD1   1 
ATOM   1472  O OD2   . ASP A 1 188  ? 204.898 345.626 265.294 1.00 69.07  ? 188  ASP A OD2   1 
ATOM   1473  N N     . LYS A 1 189  ? 207.867 346.784 264.772 1.00 68.83  ? 189  LYS A N     1 
ATOM   1474  C CA    . LYS A 1 189  ? 208.293 347.901 265.612 1.00 68.83  ? 189  LYS A CA    1 
ATOM   1475  C C     . LYS A 1 189  ? 207.774 347.754 267.037 1.00 68.83  ? 189  LYS A C     1 
ATOM   1476  O O     . LYS A 1 189  ? 208.507 348.002 268.001 1.00 68.83  ? 189  LYS A O     1 
ATOM   1477  C CB    . LYS A 1 189  ? 207.827 349.222 264.999 1.00 68.83  ? 189  LYS A CB    1 
ATOM   1478  C CG    . LYS A 1 189  ? 208.323 349.449 263.579 1.00 68.83  ? 189  LYS A CG    1 
ATOM   1479  C CD    . LYS A 1 189  ? 208.178 350.904 263.164 1.00 68.83  ? 189  LYS A CD    1 
ATOM   1480  C CE    . LYS A 1 189  ? 207.378 351.032 261.878 1.00 68.83  ? 189  LYS A CE    1 
ATOM   1481  N NZ    . LYS A 1 189  ? 207.563 352.363 261.238 1.00 68.83  ? 189  LYS A NZ    1 
ATOM   1482  N N     . THR A 1 190  ? 206.515 347.352 267.191 1.00 68.79  ? 190  THR A N     1 
ATOM   1483  C CA    . THR A 1 190  ? 205.951 347.052 268.501 1.00 68.79  ? 190  THR A CA    1 
ATOM   1484  C C     . THR A 1 190  ? 206.062 345.552 268.746 1.00 68.79  ? 190  THR A C     1 
ATOM   1485  O O     . THR A 1 190  ? 205.612 344.751 267.920 1.00 68.79  ? 190  THR A O     1 
ATOM   1486  C CB    . THR A 1 190  ? 204.493 347.503 268.587 1.00 68.79  ? 190  THR A CB    1 
ATOM   1487  O OG1   . THR A 1 190  ? 203.739 346.891 267.533 1.00 68.79  ? 190  THR A OG1   1 
ATOM   1488  C CG2   . THR A 1 190  ? 204.394 349.014 268.463 1.00 68.79  ? 190  THR A CG2   1 
ATOM   1489  N N     . ASN A 1 191  ? 206.668 345.174 269.872 1.00 67.31  ? 191  ASN A N     1 
ATOM   1490  C CA    . ASN A 1 191  ? 206.870 343.761 270.171 1.00 67.31  ? 191  ASN A CA    1 
ATOM   1491  C C     . ASN A 1 191  ? 205.536 343.038 270.299 1.00 67.31  ? 191  ASN A C     1 
ATOM   1492  O O     . ASN A 1 191  ? 205.188 342.213 269.448 1.00 67.31  ? 191  ASN A O     1 
ATOM   1493  C CB    . ASN A 1 191  ? 207.680 343.599 271.460 1.00 67.31  ? 191  ASN A CB    1 
ATOM   1494  C CG    . ASN A 1 191  ? 209.137 343.979 271.287 1.00 67.31  ? 191  ASN A CG    1 
ATOM   1495  O OD1   . ASN A 1 191  ? 210.018 343.120 271.291 1.00 67.31  ? 191  ASN A OD1   1 
ATOM   1496  N ND2   . ASN A 1 191  ? 209.400 345.273 271.137 1.00 67.31  ? 191  ASN A ND2   1 
ATOM   1497  N N     . GLN A 1 192  ? 204.781 343.360 271.352 1.00 74.67  ? 192  GLN A N     1 
ATOM   1498  C CA    . GLN A 1 192  ? 203.427 342.849 271.587 1.00 74.67  ? 192  GLN A CA    1 
ATOM   1499  C C     . GLN A 1 192  ? 203.323 341.334 271.411 1.00 74.67  ? 192  GLN A C     1 
ATOM   1500  O O     . GLN A 1 192  ? 202.232 340.807 271.171 1.00 74.67  ? 192  GLN A O     1 
ATOM   1501  C CB    . GLN A 1 192  ? 202.411 343.556 270.683 1.00 74.67  ? 192  GLN A CB    1 
ATOM   1502  C CG    . GLN A 1 192  ? 202.375 345.068 270.848 1.00 74.67  ? 192  GLN A CG    1 
ATOM   1503  C CD    . GLN A 1 192  ? 201.541 345.514 272.036 1.00 74.67  ? 192  GLN A CD    1 
ATOM   1504  O OE1   . GLN A 1 192  ? 201.254 344.731 272.941 1.00 74.67  ? 192  GLN A OE1   1 
ATOM   1505  N NE2   . GLN A 1 192  ? 201.149 346.782 272.037 1.00 74.67  ? 192  GLN A NE2   1 
ATOM   1506  N N     . GLY A 1 193  ? 204.437 340.616 271.547 1.00 75.93  ? 193  GLY A N     1 
ATOM   1507  C CA    . GLY A 1 193  ? 204.451 339.183 271.325 1.00 75.93  ? 193  GLY A CA    1 
ATOM   1508  C C     . GLY A 1 193  ? 204.011 338.776 269.932 1.00 75.93  ? 193  GLY A C     1 
ATOM   1509  O O     . GLY A 1 193  ? 203.261 337.809 269.773 1.00 75.93  ? 193  GLY A O     1 
ATOM   1510  N N     . ILE A 1 194  ? 204.469 339.506 268.911 1.00 65.49  ? 194  ILE A N     1 
ATOM   1511  C CA    . ILE A 1 194  ? 204.093 339.243 267.529 1.00 65.49  ? 194  ILE A CA    1 
ATOM   1512  C C     . ILE A 1 194  ? 205.357 339.058 266.699 1.00 65.49  ? 194  ILE A C     1 
ATOM   1513  O O     . ILE A 1 194  ? 206.428 339.572 267.027 1.00 65.49  ? 194  ILE A O     1 
ATOM   1514  C CB    . ILE A 1 194  ? 203.219 340.371 266.930 1.00 65.49  ? 194  ILE A CB    1 
ATOM   1515  C CG1   . ILE A 1 194  ? 202.243 340.915 267.973 1.00 65.49  ? 194  ILE A CG1   1 
ATOM   1516  C CG2   . ILE A 1 194  ? 202.444 339.872 265.719 1.00 65.49  ? 194  ILE A CG2   1 
ATOM   1517  C CD1   . ILE A 1 194  ? 201.437 342.102 267.489 1.00 65.49  ? 194  ILE A CD1   1 
ATOM   1518  N N     . SER A 1 195  ? 205.214 338.309 265.606 1.00 58.62  ? 195  SER A N     1 
ATOM   1519  C CA    . SER A 1 195  ? 206.294 338.070 264.662 1.00 58.62  ? 195  SER A CA    1 
ATOM   1520  C C     . SER A 1 195  ? 205.770 338.241 263.243 1.00 58.62  ? 195  SER A C     1 
ATOM   1521  O O     . SER A 1 195  ? 204.574 338.080 262.983 1.00 58.62  ? 195  SER A O     1 
ATOM   1522  C CB    . SER A 1 195  ? 206.895 336.668 264.834 1.00 58.62  ? 195  SER A CB    1 
ATOM   1523  O OG    . SER A 1 195  ? 205.879 335.696 265.011 1.00 58.62  ? 195  SER A OG    1 
ATOM   1524  N N     . GLU A 1 196  ? 206.677 338.570 262.326 1.00 58.17  ? 196  GLU A N     1 
ATOM   1525  C CA    . GLU A 1 196  ? 206.305 338.804 260.938 1.00 58.17  ? 196  GLU A CA    1 
ATOM   1526  C C     . GLU A 1 196  ? 207.453 338.387 260.031 1.00 58.17  ? 196  GLU A C     1 
ATOM   1527  O O     . GLU A 1 196  ? 208.595 338.231 260.472 1.00 58.17  ? 196  GLU A O     1 
ATOM   1528  C CB    . GLU A 1 196  ? 205.934 340.272 260.693 1.00 58.17  ? 196  GLU A CB    1 
ATOM   1529  C CG    . GLU A 1 196  ? 207.076 341.247 260.920 1.00 58.17  ? 196  GLU A CG    1 
ATOM   1530  C CD    . GLU A 1 196  ? 206.675 342.684 260.652 1.00 58.17  ? 196  GLU A CD    1 
ATOM   1531  O OE1   . GLU A 1 196  ? 205.477 343.004 260.796 1.00 58.17  ? 196  GLU A OE1   1 
ATOM   1532  O OE2   . GLU A 1 196  ? 207.558 343.494 260.298 1.00 58.17  ? 196  GLU A OE2   1 
ATOM   1533  N N     . LEU A 1 197  ? 207.130 338.205 258.752 1.00 53.38  ? 197  LEU A N     1 
ATOM   1534  C CA    . LEU A 1 197  ? 208.130 337.793 257.776 1.00 53.38  ? 197  LEU A CA    1 
ATOM   1535  C C     . LEU A 1 197  ? 209.187 338.877 257.602 1.00 53.38  ? 197  LEU A C     1 
ATOM   1536  O O     . LEU A 1 197  ? 208.892 340.073 257.657 1.00 53.38  ? 197  LEU A O     1 
ATOM   1537  C CB    . LEU A 1 197  ? 207.469 337.486 256.430 1.00 53.38  ? 197  LEU A CB    1 
ATOM   1538  C CG    . LEU A 1 197  ? 206.907 336.081 256.194 1.00 53.38  ? 197  LEU A CG    1 
ATOM   1539  C CD1   . LEU A 1 197  ? 205.765 335.761 257.149 1.00 53.38  ? 197  LEU A CD1   1 
ATOM   1540  C CD2   . LEU A 1 197  ? 206.458 335.923 254.748 1.00 53.38  ? 197  LEU A CD2   1 
ATOM   1541  N N     . ASN A 1 198  ? 210.429 338.448 257.388 1.00 49.64  ? 198  ASN A N     1 
ATOM   1542  C CA    . ASN A 1 198  ? 211.550 339.356 257.193 1.00 49.64  ? 198  ASN A CA    1 
ATOM   1543  C C     . ASN A 1 198  ? 212.301 338.966 255.929 1.00 49.64  ? 198  ASN A C     1 
ATOM   1544  O O     . ASN A 1 198  ? 212.484 337.779 255.645 1.00 49.64  ? 198  ASN A O     1 
ATOM   1545  C CB    . ASN A 1 198  ? 212.498 339.339 258.398 1.00 49.64  ? 198  ASN A CB    1 
ATOM   1546  C CG    . ASN A 1 198  ? 213.498 340.478 258.369 1.00 49.64  ? 198  ASN A CG    1 
ATOM   1547  O OD1   . ASN A 1 198  ? 214.422 340.488 257.557 1.00 49.64  ? 198  ASN A OD1   1 
ATOM   1548  N ND2   . ASN A 1 198  ? 213.317 341.447 259.259 1.00 49.64  ? 198  ASN A ND2   1 
ATOM   1549  N N     . ALA A 1 199  ? 212.734 339.977 255.170 1.00 44.05  ? 199  ALA A N     1 
ATOM   1550  C CA    . ALA A 1 199  ? 213.437 339.719 253.918 1.00 44.05  ? 199  ALA A CA    1 
ATOM   1551  C C     . ALA A 1 199  ? 214.811 339.106 254.163 1.00 44.05  ? 199  ALA A C     1 
ATOM   1552  O O     . ALA A 1 199  ? 215.260 338.246 253.395 1.00 44.05  ? 199  ALA A O     1 
ATOM   1553  C CB    . ALA A 1 199  ? 213.563 341.011 253.113 1.00 44.05  ? 199  ALA A CB    1 
ATOM   1554  N N     . SER A 1 200  ? 215.495 339.543 255.217 1.00 40.85  ? 200  SER A N     1 
ATOM   1555  C CA    . SER A 1 200  ? 216.830 339.044 255.523 1.00 40.85  ? 200  SER A CA    1 
ATOM   1556  C C     . SER A 1 200  ? 216.809 337.544 255.785 1.00 40.85  ? 200  SER A C     1 
ATOM   1557  O O     . SER A 1 200  ? 217.684 336.816 255.322 1.00 40.85  ? 200  SER A O     1 
ATOM   1558  C CB    . SER A 1 200  ? 217.417 339.780 256.729 1.00 40.85  ? 200  SER A CB    1 
ATOM   1559  O OG    . SER A 1 200  ? 218.828 339.655 256.766 1.00 40.85  ? 200  SER A OG    1 
HETATM 1560  N N     . SEP A 1 201  ? 215.798 337.090 256.518 1.00 40.07  ? 201  SEP A N     1 
HETATM 1561  C CA    . SEP A 1 201  ? 215.662 335.677 256.856 1.00 40.07  ? 201  SEP A CA    1 
HETATM 1562  C CB    . SEP A 1 201  ? 214.424 335.454 257.726 1.00 40.07  ? 201  SEP A CB    1 
HETATM 1563  C C     . SEP A 1 201  ? 215.586 334.802 255.609 1.00 40.07  ? 201  SEP A C     1 
HETATM 1564  O O     . SEP A 1 201  ? 216.381 333.873 255.445 1.00 40.07  ? 201  SEP A O     1 
ATOM   1565  N N     . VAL A 1 202  ? 214.634 335.108 254.731 1.00 38.94  ? 202  VAL A N     1 
ATOM   1566  C CA    . VAL A 1 202  ? 214.426 334.314 253.527 1.00 38.94  ? 202  VAL A CA    1 
ATOM   1567  C C     . VAL A 1 202  ? 215.622 334.435 252.587 1.00 38.94  ? 202  VAL A C     1 
ATOM   1568  O O     . VAL A 1 202  ? 216.005 333.458 251.943 1.00 38.94  ? 202  VAL A O     1 
ATOM   1569  C CB    . VAL A 1 202  ? 213.114 334.707 252.808 1.00 38.94  ? 202  VAL A CB    1 
ATOM   1570  C CG1   . VAL A 1 202  ? 211.915 334.306 253.645 1.00 38.94  ? 202  VAL A CG1   1 
ATOM   1571  C CG2   . VAL A 1 202  ? 213.076 336.196 252.512 1.00 38.94  ? 202  VAL A CG2   1 
ATOM   1572  N N     . GLY A 1 203  ? 216.227 335.624 252.522 1.00 37.78  ? 203  GLY A N     1 
ATOM   1573  C CA    . GLY A 1 203  ? 217.393 335.793 251.669 1.00 37.78  ? 203  GLY A CA    1 
ATOM   1574  C C     . GLY A 1 203  ? 218.566 334.943 252.118 1.00 37.78  ? 203  GLY A C     1 
ATOM   1575  O O     . GLY A 1 203  ? 219.201 334.256 251.311 1.00 37.78  ? 203  GLY A O     1 
ATOM   1576  N N     . MET A 1 204  ? 218.858 334.960 253.420 1.00 38.32  ? 204  MET A N     1 
ATOM   1577  C CA    . MET A 1 204  ? 219.967 334.162 253.930 1.00 38.32  ? 204  MET A CA    1 
ATOM   1578  C C     . MET A 1 204  ? 219.656 332.673 253.848 1.00 38.32  ? 204  MET A C     1 
ATOM   1579  O O     . MET A 1 204  ? 220.556 331.861 253.610 1.00 38.32  ? 204  MET A O     1 
ATOM   1580  C CB    . MET A 1 204  ? 220.303 334.572 255.363 1.00 38.32  ? 204  MET A CB    1 
ATOM   1581  C CG    . MET A 1 204  ? 220.666 336.043 255.513 1.00 38.32  ? 204  MET A CG    1 
ATOM   1582  S SD    . MET A 1 204  ? 222.390 336.409 255.141 1.00 38.32  ? 204  MET A SD    1 
ATOM   1583  C CE    . MET A 1 204  ? 223.221 335.217 256.179 1.00 38.32  ? 204  MET A CE    1 
ATOM   1584  N N     . ALA A 1 205  ? 218.388 332.293 254.035 1.00 35.29  ? 205  ALA A N     1 
ATOM   1585  C CA    . ALA A 1 205  ? 218.013 330.893 253.865 1.00 35.29  ? 205  ALA A CA    1 
ATOM   1586  C C     . ALA A 1 205  ? 218.229 330.435 252.428 1.00 35.29  ? 205  ALA A C     1 
ATOM   1587  O O     . ALA A 1 205  ? 218.756 329.341 252.189 1.00 35.29  ? 205  ALA A O     1 
ATOM   1588  C CB    . ALA A 1 205  ? 216.558 330.684 254.284 1.00 35.29  ? 205  ALA A CB    1 
ATOM   1589  N N     . LYS A 1 206  ? 217.836 331.263 251.457 1.00 38.64  ? 206  LYS A N     1 
ATOM   1590  C CA    . LYS A 1 206  ? 218.061 330.924 250.055 1.00 38.64  ? 206  LYS A CA    1 
ATOM   1591  C C     . LYS A 1 206  ? 219.549 330.829 249.745 1.00 38.64  ? 206  LYS A C     1 
ATOM   1592  O O     . LYS A 1 206  ? 219.984 329.929 249.017 1.00 38.64  ? 206  LYS A O     1 
ATOM   1593  C CB    . LYS A 1 206  ? 217.385 331.957 249.152 1.00 38.64  ? 206  LYS A CB    1 
ATOM   1594  C CG    . LYS A 1 206  ? 218.183 332.323 247.910 1.00 38.64  ? 206  LYS A CG    1 
ATOM   1595  C CD    . LYS A 1 206  ? 217.367 333.167 246.949 1.00 38.64  ? 206  LYS A CD    1 
ATOM   1596  C CE    . LYS A 1 206  ? 218.041 333.248 245.590 1.00 38.64  ? 206  LYS A CE    1 
ATOM   1597  N NZ    . LYS A 1 206  ? 219.505 333.492 245.710 1.00 38.64  ? 206  LYS A NZ    1 
ATOM   1598  N N     . ALA A 1 207  ? 220.347 331.751 250.291 1.00 35.87  ? 207  ALA A N     1 
ATOM   1599  C CA    . ALA A 1 207  ? 221.788 331.702 250.061 1.00 35.87  ? 207  ALA A CA    1 
ATOM   1600  C C     . ALA A 1 207  ? 222.403 330.442 250.659 1.00 35.87  ? 207  ALA A C     1 
ATOM   1601  O O     . ALA A 1 207  ? 223.275 329.815 250.044 1.00 35.87  ? 207  ALA A O     1 
ATOM   1602  C CB    . ALA A 1 207  ? 222.453 332.949 250.638 1.00 35.87  ? 207  ALA A CB    1 
ATOM   1603  N N     . ALA A 1 208  ? 221.967 330.058 251.861 1.00 31.71  ? 208  ALA A N     1 
ATOM   1604  C CA    . ALA A 1 208  ? 222.472 328.838 252.481 1.00 31.71  ? 208  ALA A CA    1 
ATOM   1605  C C     . ALA A 1 208  ? 222.079 327.607 251.675 1.00 31.71  ? 208  ALA A C     1 
ATOM   1606  O O     . ALA A 1 208  ? 222.878 326.676 251.520 1.00 31.71  ? 208  ALA A O     1 
ATOM   1607  C CB    . ALA A 1 208  ? 221.959 328.727 253.917 1.00 31.71  ? 208  ALA A CB    1 
ATOM   1608  N N     . LEU A 1 209  ? 220.846 327.580 251.162 1.00 34.41  ? 209  LEU A N     1 
ATOM   1609  C CA    . LEU A 1 209  ? 220.425 326.465 250.318 1.00 34.41  ? 209  LEU A CA    1 
ATOM   1610  C C     . LEU A 1 209  ? 221.255 326.398 249.041 1.00 34.41  ? 209  LEU A C     1 
ATOM   1611  O O     . LEU A 1 209  ? 221.627 325.309 248.589 1.00 34.41  ? 209  LEU A O     1 
ATOM   1612  C CB    . LEU A 1 209  ? 218.937 326.587 249.987 1.00 34.41  ? 209  LEU A CB    1 
ATOM   1613  C CG    . LEU A 1 209  ? 217.958 326.407 251.149 1.00 34.41  ? 209  LEU A CG    1 
ATOM   1614  C CD1   . LEU A 1 209  ? 216.586 326.954 250.785 1.00 34.41  ? 209  LEU A CD1   1 
ATOM   1615  C CD2   . LEU A 1 209  ? 217.866 324.947 251.565 1.00 34.41  ? 209  LEU A CD2   1 
ATOM   1616  N N     . GLU A 1 210  ? 221.549 327.555 248.442 1.00 37.16  ? 210  GLU A N     1 
ATOM   1617  C CA    . GLU A 1 210  ? 222.376 327.581 247.239 1.00 37.16  ? 210  GLU A CA    1 
ATOM   1618  C C     . GLU A 1 210  ? 223.791 327.095 247.525 1.00 37.16  ? 210  GLU A C     1 
ATOM   1619  O O     . GLU A 1 210  ? 224.378 326.362 246.721 1.00 37.16  ? 210  GLU A O     1 
ATOM   1620  C CB    . GLU A 1 210  ? 222.407 328.993 246.653 1.00 37.16  ? 210  GLU A CB    1 
ATOM   1621  C CG    . GLU A 1 210  ? 221.225 329.323 245.760 1.00 37.16  ? 210  GLU A CG    1 
ATOM   1622  C CD    . GLU A 1 210  ? 221.500 330.497 244.841 1.00 37.16  ? 210  GLU A CD    1 
ATOM   1623  O OE1   . GLU A 1 210  ? 221.841 331.586 245.350 1.00 37.16  ? 210  GLU A OE1   1 
ATOM   1624  O OE2   . GLU A 1 210  ? 221.376 330.332 243.609 1.00 37.16  ? 210  GLU A OE2   1 
ATOM   1625  N N     . ALA A 1 211  ? 224.359 327.501 248.664 1.00 32.60  ? 211  ALA A N     1 
ATOM   1626  C CA    . ALA A 1 211  ? 225.730 327.119 248.989 1.00 32.60  ? 211  ALA A CA    1 
ATOM   1627  C C     . ALA A 1 211  ? 225.859 325.614 249.191 1.00 32.60  ? 211  ALA A C     1 
ATOM   1628  O O     . ALA A 1 211  ? 226.850 325.008 248.767 1.00 32.60  ? 211  ALA A O     1 
ATOM   1629  C CB    . ALA A 1 211  ? 226.201 327.869 250.234 1.00 32.60  ? 211  ALA A CB    1 
ATOM   1630  N N     . LEU A 1 212  ? 224.869 324.992 249.836 1.00 32.19  ? 212  LEU A N     1 
ATOM   1631  C CA    . LEU A 1 212  ? 224.896 323.564 250.130 1.00 32.19  ? 212  LEU A CA    1 
ATOM   1632  C C     . LEU A 1 212  ? 224.151 322.735 249.091 1.00 32.19  ? 212  LEU A C     1 
ATOM   1633  O O     . LEU A 1 212  ? 223.584 321.687 249.432 1.00 32.19  ? 212  LEU A O     1 
ATOM   1634  C CB    . LEU A 1 212  ? 224.323 323.308 251.524 1.00 32.19  ? 212  LEU A CB    1 
ATOM   1635  C CG    . LEU A 1 212  ? 225.199 323.720 252.709 1.00 32.19  ? 212  LEU A CG    1 
ATOM   1636  C CD1   . LEU A 1 212  ? 224.345 324.000 253.936 1.00 32.19  ? 212  LEU A CD1   1 
ATOM   1637  C CD2   . LEU A 1 212  ? 226.235 322.649 253.007 1.00 32.19  ? 212  LEU A CD2   1 
ATOM   1638  N N     . ASP A 1 213  ? 224.133 323.177 247.831 1.00 37.45  ? 213  ASP A N     1 
ATOM   1639  C CA    . ASP A 1 213  ? 223.401 322.451 246.797 1.00 37.45  ? 213  ASP A CA    1 
ATOM   1640  C C     . ASP A 1 213  ? 223.985 321.060 246.578 1.00 37.45  ? 213  ASP A C     1 
ATOM   1641  O O     . ASP A 1 213  ? 223.258 320.060 246.587 1.00 37.45  ? 213  ASP A O     1 
ATOM   1642  C CB    . ASP A 1 213  ? 223.407 323.250 245.494 1.00 37.45  ? 213  ASP A CB    1 
ATOM   1643  C CG    . ASP A 1 213  ? 222.166 323.012 244.657 1.00 37.45  ? 213  ASP A CG    1 
ATOM   1644  O OD1   . ASP A 1 213  ? 221.647 321.875 244.669 1.00 37.45  ? 213  ASP A OD1   1 
ATOM   1645  O OD2   . ASP A 1 213  ? 221.709 323.961 243.985 1.00 37.45  ? 213  ASP A OD2   1 
ATOM   1646  N N     . GLU A 1 214  ? 225.303 320.976 246.373 1.00 35.42  ? 214  GLU A N     1 
ATOM   1647  C CA    . GLU A 1 214  ? 225.970 319.695 246.168 1.00 35.42  ? 214  GLU A CA    1 
ATOM   1648  C C     . GLU A 1 214  ? 227.315 319.643 246.885 1.00 35.42  ? 214  GLU A C     1 
ATOM   1649  O O     . GLU A 1 214  ? 228.236 318.955 246.431 1.00 35.42  ? 214  GLU A O     1 
ATOM   1650  C CB    . GLU A 1 214  ? 226.164 319.402 244.677 1.00 35.42  ? 214  GLU A CB    1 
ATOM   1651  C CG    . GLU A 1 214  ? 224.879 319.088 243.920 1.00 35.42  ? 214  GLU A CG    1 
ATOM   1652  C CD    . GLU A 1 214  ? 224.481 317.625 244.012 1.00 35.42  ? 214  GLU A CD    1 
ATOM   1653  O OE1   . GLU A 1 214  ? 224.479 317.071 245.131 1.00 35.42  ? 214  GLU A OE1   1 
ATOM   1654  O OE2   . GLU A 1 214  ? 224.169 317.028 242.960 1.00 35.42  ? 214  GLU A OE2   1 
ATOM   1655  N N     . LEU A 1 215  ? 227.447 320.362 247.996 1.00 32.90  ? 215  LEU A N     1 
ATOM   1656  C CA    . LEU A 1 215  ? 228.716 320.414 248.709 1.00 32.90  ? 215  LEU A CA    1 
ATOM   1657  C C     . LEU A 1 215  ? 229.038 319.072 249.354 1.00 32.90  ? 215  LEU A C     1 
ATOM   1658  O O     . LEU A 1 215  ? 228.151 318.370 249.849 1.00 32.90  ? 215  LEU A O     1 
ATOM   1659  C CB    . LEU A 1 215  ? 228.680 321.507 249.775 1.00 32.90  ? 215  LEU A CB    1 
ATOM   1660  C CG    . LEU A 1 215  ? 230.024 321.848 250.422 1.00 32.90  ? 215  LEU A CG    1 
ATOM   1661  C CD1   . LEU A 1 215  ? 230.740 322.943 249.645 1.00 32.90  ? 215  LEU A CD1   1 
ATOM   1662  C CD2   . LEU A 1 215  ? 229.837 322.242 251.877 1.00 32.90  ? 215  LEU A CD2   1 
ATOM   1663  N N     . ASP A 1 216  ? 230.322 318.718 249.346 1.00 35.05  ? 216  ASP A N     1 
ATOM   1664  C CA    . ASP A 1 216  ? 230.819 317.514 250.003 1.00 35.05  ? 216  ASP A CA    1 
ATOM   1665  C C     . ASP A 1 216  ? 231.426 317.924 251.341 1.00 35.05  ? 216  ASP A C     1 
ATOM   1666  O O     . ASP A 1 216  ? 232.463 318.594 251.380 1.00 35.05  ? 216  ASP A O     1 
ATOM   1667  C CB    . ASP A 1 216  ? 231.844 316.799 249.124 1.00 35.05  ? 216  ASP A CB    1 
ATOM   1668  C CG    . ASP A 1 216  ? 232.106 315.373 249.571 1.00 35.05  ? 216  ASP A CG    1 
ATOM   1669  O OD1   . ASP A 1 216  ? 231.634 314.989 250.662 1.00 35.05  ? 216  ASP A OD1   1 
ATOM   1670  O OD2   . ASP A 1 216  ? 232.785 314.634 248.829 1.00 35.05  ? 216  ASP A OD2   1 
ATOM   1671  N N     . LEU A 1 217  ? 230.777 317.521 252.435 1.00 31.34  ? 217  LEU A N     1 
ATOM   1672  C CA    . LEU A 1 217  ? 231.220 317.913 253.768 1.00 31.34  ? 217  LEU A CA    1 
ATOM   1673  C C     . LEU A 1 217  ? 232.537 317.266 254.176 1.00 31.34  ? 217  LEU A C     1 
ATOM   1674  O O     . LEU A 1 217  ? 233.195 317.772 255.091 1.00 31.34  ? 217  LEU A O     1 
ATOM   1675  C CB    . LEU A 1 217  ? 230.142 317.572 254.799 1.00 31.34  ? 217  LEU A CB    1 
ATOM   1676  C CG    . LEU A 1 217  ? 228.811 318.313 254.659 1.00 31.34  ? 217  LEU A CG    1 
ATOM   1677  C CD1   . LEU A 1 217  ? 227.709 317.584 255.412 1.00 31.34  ? 217  LEU A CD1   1 
ATOM   1678  C CD2   . LEU A 1 217  ? 228.941 319.748 255.146 1.00 31.34  ? 217  LEU A CD2   1 
ATOM   1679  N N     . PHE A 1 218  ? 232.938 316.173 253.529 1.00 33.63  ? 218  PHE A N     1 
ATOM   1680  C CA    . PHE A 1 218  ? 234.170 315.473 253.865 1.00 33.63  ? 218  PHE A CA    1 
ATOM   1681  C C     . PHE A 1 218  ? 235.351 315.918 253.011 1.00 33.63  ? 218  PHE A C     1 
ATOM   1682  O O     . PHE A 1 218  ? 236.437 315.342 253.127 1.00 33.63  ? 218  PHE A O     1 
ATOM   1683  C CB    . PHE A 1 218  ? 233.970 313.962 253.735 1.00 33.63  ? 218  PHE A CB    1 
ATOM   1684  C CG    . PHE A 1 218  ? 233.572 313.290 255.018 1.00 33.63  ? 218  PHE A CG    1 
ATOM   1685  C CD1   . PHE A 1 218  ? 232.541 313.797 255.791 1.00 33.63  ? 218  PHE A CD1   1 
ATOM   1686  C CD2   . PHE A 1 218  ? 234.228 312.150 255.450 1.00 33.63  ? 218  PHE A CD2   1 
ATOM   1687  C CE1   . PHE A 1 218  ? 232.172 313.180 256.972 1.00 33.63  ? 218  PHE A CE1   1 
ATOM   1688  C CE2   . PHE A 1 218  ? 233.865 311.528 256.630 1.00 33.63  ? 218  PHE A CE2   1 
ATOM   1689  C CZ    . PHE A 1 218  ? 232.836 312.044 257.392 1.00 33.63  ? 218  PHE A CZ    1 
ATOM   1690  N N     . GLY A 1 219  ? 235.166 316.924 252.161 1.00 32.94  ? 219  GLY A N     1 
ATOM   1691  C CA    . GLY A 1 219  ? 236.251 317.414 251.337 1.00 32.94  ? 219  GLY A CA    1 
ATOM   1692  C C     . GLY A 1 219  ? 236.501 316.547 250.115 1.00 32.94  ? 219  GLY A C     1 
ATOM   1693  O O     . GLY A 1 219  ? 235.620 315.840 249.614 1.00 32.94  ? 219  GLY A O     1 
ATOM   1694  N N     . VAL A 1 220  ? 237.743 316.617 249.627 1.00 33.43  ? 220  VAL A N     1 
ATOM   1695  C CA    . VAL A 1 220  ? 238.123 315.870 248.431 1.00 33.43  ? 220  VAL A CA    1 
ATOM   1696  C C     . VAL A 1 220  ? 238.069 314.369 248.679 1.00 33.43  ? 220  VAL A C     1 
ATOM   1697  O O     . VAL A 1 220  ? 237.860 313.585 247.746 1.00 33.43  ? 220  VAL A O     1 
ATOM   1698  C CB    . VAL A 1 220  ? 239.520 316.312 247.949 1.00 33.43  ? 220  VAL A CB    1 
ATOM   1699  C CG1   . VAL A 1 220  ? 239.474 317.742 247.435 1.00 33.43  ? 220  VAL A CG1   1 
ATOM   1700  C CG2   . VAL A 1 220  ? 240.539 316.177 249.070 1.00 33.43  ? 220  VAL A CG2   1 
ATOM   1701  N N     . LYS A 1 221  ? 238.255 313.942 249.927 1.00 31.46  ? 221  LYS A N     1 
ATOM   1702  C CA    . LYS A 1 221  ? 238.240 312.525 250.265 1.00 31.46  ? 221  LYS A CA    1 
ATOM   1703  C C     . LYS A 1 221  ? 236.834 311.978 250.479 1.00 31.46  ? 221  LYS A C     1 
ATOM   1704  O O     . LYS A 1 221  ? 236.688 310.779 250.740 1.00 31.46  ? 221  LYS A O     1 
ATOM   1705  C CB    . LYS A 1 221  ? 239.083 312.276 251.519 1.00 31.46  ? 221  LYS A CB    1 
ATOM   1706  C CG    . LYS A 1 221  ? 240.529 312.726 251.396 1.00 31.46  ? 221  LYS A CG    1 
ATOM   1707  C CD    . LYS A 1 221  ? 241.351 312.274 252.592 1.00 31.46  ? 221  LYS A CD    1 
ATOM   1708  C CE    . LYS A 1 221  ? 240.887 312.953 253.870 1.00 31.46  ? 221  LYS A CE    1 
ATOM   1709  N NZ    . LYS A 1 221  ? 240.889 314.437 253.743 1.00 31.46  ? 221  LYS A NZ    1 
ATOM   1710  N N     . GLY A 1 222  ? 235.806 312.817 250.379 1.00 28.34  ? 222  GLY A N     1 
ATOM   1711  C CA    . GLY A 1 222  ? 234.454 312.349 250.608 1.00 28.34  ? 222  GLY A CA    1 
ATOM   1712  C C     . GLY A 1 222  ? 233.940 311.488 249.470 1.00 28.34  ? 222  GLY A C     1 
ATOM   1713  O O     . GLY A 1 222  ? 234.435 311.533 248.344 1.00 28.34  ? 222  GLY A O     1 
ATOM   1714  N N     . GLY A 1 223  ? 232.923 310.689 249.781 1.00 37.69  ? 223  GLY A N     1 
ATOM   1715  C CA    . GLY A 1 223  ? 232.308 309.820 248.807 1.00 37.69  ? 223  GLY A CA    1 
ATOM   1716  C C     . GLY A 1 223  ? 230.895 310.247 248.467 1.00 37.69  ? 223  GLY A C     1 
ATOM   1717  O O     . GLY A 1 223  ? 230.413 311.295 248.908 1.00 37.69  ? 223  GLY A O     1 
ATOM   1718  N N     . PRO A 1 224  ? 230.202 309.437 247.663 1.00 38.88  ? 224  PRO A N     1 
ATOM   1719  C CA    . PRO A 1 224  ? 228.817 309.775 247.297 1.00 38.88  ? 224  PRO A CA    1 
ATOM   1720  C C     . PRO A 1 224  ? 227.853 309.764 248.470 1.00 38.88  ? 224  PRO A C     1 
ATOM   1721  O O     . PRO A 1 224  ? 226.768 310.349 248.364 1.00 38.88  ? 224  PRO A O     1 
ATOM   1722  C CB    . PRO A 1 224  ? 228.454 308.700 246.263 1.00 38.88  ? 224  PRO A CB    1 
ATOM   1723  C CG    . PRO A 1 224  ? 229.368 307.560 246.564 1.00 38.88  ? 224  PRO A CG    1 
ATOM   1724  C CD    . PRO A 1 224  ? 230.646 308.166 247.065 1.00 38.88  ? 224  PRO A CD    1 
ATOM   1725  N N     . GLN A 1 225  ? 228.205 309.118 249.580 1.00 39.46  ? 225  GLN A N     1 
ATOM   1726  C CA    . GLN A 1 225  ? 227.319 309.019 250.732 1.00 39.46  ? 225  GLN A CA    1 
ATOM   1727  C C     . GLN A 1 225  ? 227.357 310.258 251.621 1.00 39.46  ? 225  GLN A C     1 
ATOM   1728  O O     . GLN A 1 225  ? 226.518 310.384 252.520 1.00 39.46  ? 225  GLN A O     1 
ATOM   1729  C CB    . GLN A 1 225  ? 227.678 307.772 251.551 1.00 39.46  ? 225  GLN A CB    1 
ATOM   1730  C CG    . GLN A 1 225  ? 226.618 307.331 252.551 1.00 39.46  ? 225  GLN A CG    1 
ATOM   1731  C CD    . GLN A 1 225  ? 225.217 307.372 251.972 1.00 39.46  ? 225  GLN A CD    1 
ATOM   1732  O OE1   . GLN A 1 225  ? 224.373 308.151 252.414 1.00 39.46  ? 225  GLN A OE1   1 
ATOM   1733  N NE2   . GLN A 1 225  ? 224.963 306.529 250.977 1.00 39.46  ? 225  GLN A NE2   1 
ATOM   1734  N N     . SER A 1 226  ? 228.286 311.183 251.383 1.00 33.69  ? 226  SER A N     1 
ATOM   1735  C CA    . SER A 1 226  ? 228.433 312.347 252.248 1.00 33.69  ? 226  SER A CA    1 
ATOM   1736  C C     . SER A 1 226  ? 228.193 313.644 251.485 1.00 33.69  ? 226  SER A C     1 
ATOM   1737  O O     . SER A 1 226  ? 228.963 314.601 251.620 1.00 33.69  ? 226  SER A O     1 
ATOM   1738  C CB    . SER A 1 226  ? 229.823 312.360 252.890 1.00 33.69  ? 226  SER A CB    1 
ATOM   1739  O OG    . SER A 1 226  ? 230.170 313.661 253.330 1.00 33.69  ? 226  SER A OG    1 
ATOM   1740  N N     . VAL A 1 227  ? 227.131 313.688 250.685 1.00 33.02  ? 227  VAL A N     1 
ATOM   1741  C CA    . VAL A 1 227  ? 226.768 314.870 249.912 1.00 33.02  ? 227  VAL A CA    1 
ATOM   1742  C C     . VAL A 1 227  ? 225.373 315.311 250.335 1.00 33.02  ? 227  VAL A C     1 
ATOM   1743  O O     . VAL A 1 227  ? 224.504 314.472 250.603 1.00 33.02  ? 227  VAL A O     1 
ATOM   1744  C CB    . VAL A 1 227  ? 226.828 314.607 248.395 1.00 33.02  ? 227  VAL A CB    1 
ATOM   1745  C CG1   . VAL A 1 227  ? 228.263 314.347 247.961 1.00 33.02  ? 227  VAL A CG1   1 
ATOM   1746  C CG2   . VAL A 1 227  ? 225.932 313.439 248.012 1.00 33.02  ? 227  VAL A CG2   1 
ATOM   1747  N N     . ILE A 1 228  ? 225.169 316.621 250.413 1.00 31.40  ? 228  ILE A N     1 
ATOM   1748  C CA    . ILE A 1 228  ? 223.887 317.193 250.806 1.00 31.40  ? 228  ILE A CA    1 
ATOM   1749  C C     . ILE A 1 228  ? 223.102 317.545 249.550 1.00 31.40  ? 228  ILE A C     1 
ATOM   1750  O O     . ILE A 1 228  ? 223.630 318.191 248.637 1.00 31.40  ? 228  ILE A O     1 
ATOM   1751  C CB    . ILE A 1 228  ? 224.085 318.430 251.698 1.00 31.40  ? 228  ILE A CB    1 
ATOM   1752  C CG1   . ILE A 1 228  ? 224.926 318.072 252.925 1.00 31.40  ? 228  ILE A CG1   1 
ATOM   1753  C CG2   . ILE A 1 228  ? 222.743 319.009 252.117 1.00 31.40  ? 228  ILE A CG2   1 
ATOM   1754  C CD1   . ILE A 1 228  ? 224.323 316.979 253.778 1.00 31.40  ? 228  ILE A CD1   1 
ATOM   1755  N N     . HIS A 1 229  ? 221.843 317.118 249.501 1.00 35.09  ? 229  HIS A N     1 
ATOM   1756  C CA    . HIS A 1 229  ? 220.970 317.376 248.364 1.00 35.09  ? 229  HIS A CA    1 
ATOM   1757  C C     . HIS A 1 229  ? 219.940 318.433 248.741 1.00 35.09  ? 229  HIS A C     1 
ATOM   1758  O O     . HIS A 1 229  ? 219.255 318.304 249.761 1.00 35.09  ? 229  HIS A O     1 
ATOM   1759  C CB    . HIS A 1 229  ? 220.272 316.092 247.913 1.00 35.09  ? 229  HIS A CB    1 
ATOM   1760  C CG    . HIS A 1 229  ? 221.214 315.023 247.453 1.00 35.09  ? 229  HIS A CG    1 
ATOM   1761  N ND1   . HIS A 1 229  ? 222.092 315.204 246.406 1.00 35.09  ? 229  HIS A ND1   1 
ATOM   1762  C CD2   . HIS A 1 229  ? 221.418 313.761 247.901 1.00 35.09  ? 229  HIS A CD2   1 
ATOM   1763  C CE1   . HIS A 1 229  ? 222.794 314.099 246.227 1.00 35.09  ? 229  HIS A CE1   1 
ATOM   1764  N NE2   . HIS A 1 229  ? 222.405 313.208 247.121 1.00 35.09  ? 229  HIS A NE2   1 
ATOM   1765  N N     . VAL A 1 230  ? 219.834 319.472 247.916 1.00 35.63  ? 230  VAL A N     1 
ATOM   1766  C CA    . VAL A 1 230  ? 218.923 320.586 248.154 1.00 35.63  ? 230  VAL A CA    1 
ATOM   1767  C C     . VAL A 1 230  ? 218.084 320.801 246.904 1.00 35.63  ? 230  VAL A C     1 
ATOM   1768  O O     . VAL A 1 230  ? 218.622 320.863 245.793 1.00 35.63  ? 230  VAL A O     1 
ATOM   1769  C CB    . VAL A 1 230  ? 219.682 321.874 248.528 1.00 35.63  ? 230  VAL A CB    1 
ATOM   1770  C CG1   . VAL A 1 230  ? 218.737 323.065 248.547 1.00 35.63  ? 230  VAL A CG1   1 
ATOM   1771  C CG2   . VAL A 1 230  ? 220.366 321.714 249.876 1.00 35.63  ? 230  VAL A CG2   1 
ATOM   1772  N N     . LEU A 1 231  ? 216.770 320.914 247.085 1.00 41.18  ? 231  LEU A N     1 
ATOM   1773  C CA    . LEU A 1 231  ? 215.873 321.168 245.969 1.00 41.18  ? 231  LEU A CA    1 
ATOM   1774  C C     . LEU A 1 231  ? 216.073 322.581 245.427 1.00 41.18  ? 231  LEU A C     1 
ATOM   1775  O O     . LEU A 1 231  ? 216.496 323.498 246.137 1.00 41.18  ? 231  LEU A O     1 
ATOM   1776  C CB    . LEU A 1 231  ? 214.417 320.975 246.394 1.00 41.18  ? 231  LEU A CB    1 
ATOM   1777  C CG    . LEU A 1 231  ? 214.088 319.734 247.225 1.00 41.18  ? 231  LEU A CG    1 
ATOM   1778  C CD1   . LEU A 1 231  ? 212.596 319.666 247.508 1.00 41.18  ? 231  LEU A CD1   1 
ATOM   1779  C CD2   . LEU A 1 231  ? 214.557 318.473 246.515 1.00 41.18  ? 231  LEU A CD2   1 
ATOM   1780  N N     . ALA A 1 232  ? 215.759 322.748 244.143 1.00 44.03  ? 232  ALA A N     1 
ATOM   1781  C CA    . ALA A 1 232  ? 215.854 324.050 243.499 1.00 44.03  ? 232  ALA A CA    1 
ATOM   1782  C C     . ALA A 1 232  ? 214.550 324.832 243.541 1.00 44.03  ? 232  ALA A C     1 
ATOM   1783  O O     . ALA A 1 232  ? 214.572 326.054 243.359 1.00 44.03  ? 232  ALA A O     1 
ATOM   1784  C CB    . ALA A 1 232  ? 216.302 323.890 242.042 1.00 44.03  ? 232  ALA A CB    1 
ATOM   1785  N N     . ASP A 1 233  ? 213.419 324.158 243.771 1.00 50.14  ? 233  ASP A N     1 
ATOM   1786  C CA    . ASP A 1 233  ? 212.138 324.855 243.827 1.00 50.14  ? 233  ASP A CA    1 
ATOM   1787  C C     . ASP A 1 233  ? 212.088 325.835 244.992 1.00 50.14  ? 233  ASP A C     1 
ATOM   1788  O O     . ASP A 1 233  ? 211.591 326.958 244.848 1.00 50.14  ? 233  ASP A O     1 
ATOM   1789  C CB    . ASP A 1 233  ? 210.996 323.844 243.926 1.00 50.14  ? 233  ASP A CB    1 
ATOM   1790  C CG    . ASP A 1 233  ? 210.489 323.403 242.568 1.00 50.14  ? 233  ASP A CG    1 
ATOM   1791  O OD1   . ASP A 1 233  ? 210.089 324.276 241.769 1.00 50.14  ? 233  ASP A OD1   1 
ATOM   1792  O OD2   . ASP A 1 233  ? 210.491 322.183 242.299 1.00 50.14  ? 233  ASP A OD2   1 
ATOM   1793  N N     . GLU A 1 234  ? 212.596 325.425 246.158 1.00 49.28  ? 234  GLU A N     1 
ATOM   1794  C CA    . GLU A 1 234  ? 212.590 326.306 247.321 1.00 49.28  ? 234  GLU A CA    1 
ATOM   1795  C C     . GLU A 1 234  ? 213.441 327.546 247.080 1.00 49.28  ? 234  GLU A C     1 
ATOM   1796  O O     . GLU A 1 234  ? 213.058 328.656 247.470 1.00 49.28  ? 234  GLU A O     1 
ATOM   1797  C CB    . GLU A 1 234  ? 213.081 325.549 248.556 1.00 49.28  ? 234  GLU A CB    1 
ATOM   1798  C CG    . GLU A 1 234  ? 212.309 324.272 248.854 1.00 49.28  ? 234  GLU A CG    1 
ATOM   1799  C CD    . GLU A 1 234  ? 210.854 324.532 249.195 1.00 49.28  ? 234  GLU A CD    1 
ATOM   1800  O OE1   . GLU A 1 234  ? 210.553 325.608 249.754 1.00 49.28  ? 234  GLU A OE1   1 
ATOM   1801  O OE2   . GLU A 1 234  ? 210.010 323.658 248.904 1.00 49.28  ? 234  GLU A OE2   1 
ATOM   1802  N N     . VAL A 1 235  ? 214.600 327.377 246.440 1.00 42.62  ? 235  VAL A N     1 
ATOM   1803  C CA    . VAL A 1 235  ? 215.480 328.513 246.173 1.00 42.62  ? 235  VAL A CA    1 
ATOM   1804  C C     . VAL A 1 235  ? 214.794 329.513 245.250 1.00 42.62  ? 235  VAL A C     1 
ATOM   1805  O O     . VAL A 1 235  ? 214.832 330.727 245.483 1.00 42.62  ? 235  VAL A O     1 
ATOM   1806  C CB    . VAL A 1 235  ? 216.816 328.028 245.583 1.00 42.62  ? 235  VAL A CB    1 
ATOM   1807  C CG1   . VAL A 1 235  ? 217.677 329.213 245.178 1.00 42.62  ? 235  VAL A CG1   1 
ATOM   1808  C CG2   . VAL A 1 235  ? 217.548 327.147 246.583 1.00 42.62  ? 235  VAL A CG2   1 
ATOM   1809  N N     . GLN A 1 236  ? 214.156 329.017 244.187 1.00 49.40  ? 236  GLN A N     1 
ATOM   1810  C CA    . GLN A 1 236  ? 213.476 329.911 243.254 1.00 49.40  ? 236  GLN A CA    1 
ATOM   1811  C C     . GLN A 1 236  ? 212.278 330.588 243.907 1.00 49.40  ? 236  GLN A C     1 
ATOM   1812  O O     . GLN A 1 236  ? 212.007 331.767 243.648 1.00 49.40  ? 236  GLN A O     1 
ATOM   1813  C CB    . GLN A 1 236  ? 213.050 329.141 242.006 1.00 49.40  ? 236  GLN A CB    1 
ATOM   1814  C CG    . GLN A 1 236  ? 214.203 328.479 241.270 1.00 49.40  ? 236  GLN A CG    1 
ATOM   1815  C CD    . GLN A 1 236  ? 215.461 329.325 241.266 1.00 49.40  ? 236  GLN A CD    1 
ATOM   1816  O OE1   . GLN A 1 236  ? 215.453 330.472 240.815 1.00 49.40  ? 236  GLN A OE1   1 
ATOM   1817  N NE2   . GLN A 1 236  ? 216.549 328.766 241.780 1.00 49.40  ? 236  GLN A NE2   1 
ATOM   1818  N N     . HIS A 1 237  ? 211.546 329.860 244.754 1.00 55.02  ? 237  HIS A N     1 
ATOM   1819  C CA    . HIS A 1 237  ? 210.433 330.469 245.474 1.00 55.02  ? 237  HIS A CA    1 
ATOM   1820  C C     . HIS A 1 237  ? 210.920 331.577 246.398 1.00 55.02  ? 237  HIS A C     1 
ATOM   1821  O O     . HIS A 1 237  ? 210.311 332.651 246.466 1.00 55.02  ? 237  HIS A O     1 
ATOM   1822  C CB    . HIS A 1 237  ? 209.669 329.405 246.261 1.00 55.02  ? 237  HIS A CB    1 
ATOM   1823  C CG    . HIS A 1 237  ? 208.734 328.591 245.423 1.00 55.02  ? 237  HIS A CG    1 
ATOM   1824  N ND1   . HIS A 1 237  ? 207.830 329.159 244.551 1.00 55.02  ? 237  HIS A ND1   1 
ATOM   1825  C CD2   . HIS A 1 237  ? 208.561 327.251 245.323 1.00 55.02  ? 237  HIS A CD2   1 
ATOM   1826  C CE1   . HIS A 1 237  ? 207.141 328.205 243.950 1.00 55.02  ? 237  HIS A CE1   1 
ATOM   1827  N NE2   . HIS A 1 237  ? 207.566 327.038 244.401 1.00 55.02  ? 237  HIS A NE2   1 
ATOM   1828  N N     . CYS A 1 238  ? 212.025 331.339 247.111 1.00 49.45  ? 238  CYS A N     1 
ATOM   1829  C CA    . CYS A 1 238  ? 212.591 332.374 247.971 1.00 49.45  ? 238  CYS A CA    1 
ATOM   1830  C C     . CYS A 1 238  ? 213.065 333.571 247.157 1.00 49.45  ? 238  CYS A C     1 
ATOM   1831  O O     . CYS A 1 238  ? 212.898 334.721 247.578 1.00 49.45  ? 238  CYS A O     1 
ATOM   1832  C CB    . CYS A 1 238  ? 213.739 331.800 248.802 1.00 49.45  ? 238  CYS A CB    1 
ATOM   1833  S SG    . CYS A 1 238  ? 213.237 330.557 250.016 1.00 49.45  ? 238  CYS A SG    1 
ATOM   1834  N N     . GLN A 1 239  ? 213.664 333.324 245.996 1.00 48.71  ? 239  GLN A N     1 
ATOM   1835  C CA    . GLN A 1 239  ? 214.109 334.398 245.113 1.00 48.71  ? 239  GLN A CA    1 
ATOM   1836  C C     . GLN A 1 239  ? 212.938 335.261 244.656 1.00 48.71  ? 239  GLN A C     1 
ATOM   1837  O O     . GLN A 1 239  ? 213.011 336.489 244.690 1.00 48.71  ? 239  GLN A O     1 
ATOM   1838  C CB    . GLN A 1 239  ? 214.841 333.828 243.896 1.00 48.71  ? 239  GLN A CB    1 
ATOM   1839  C CG    . GLN A 1 239  ? 215.033 334.828 242.764 1.00 48.71  ? 239  GLN A CG    1 
ATOM   1840  C CD    . GLN A 1 239  ? 216.359 335.559 242.842 1.00 48.71  ? 239  GLN A CD    1 
ATOM   1841  O OE1   . GLN A 1 239  ? 217.419 334.939 242.920 1.00 48.71  ? 239  GLN A OE1   1 
ATOM   1842  N NE2   . GLN A 1 239  ? 216.305 336.885 242.821 1.00 48.71  ? 239  GLN A NE2   1 
HETATM 1843  N N     . SEP A 1 240  ? 211.860 334.611 244.230 1.00 51.91  ? 240  SEP A N     1 
HETATM 1844  C CA    . SEP A 1 240  ? 210.664 335.317 243.784 1.00 51.91  ? 240  SEP A CA    1 
HETATM 1845  C CB    . SEP A 1 240  ? 209.647 334.336 243.199 1.00 51.91  ? 240  SEP A CB    1 
HETATM 1846  C C     . SEP A 1 240  ? 210.036 336.107 244.929 1.00 51.91  ? 240  SEP A C     1 
HETATM 1847  O O     . SEP A 1 240  ? 209.576 337.236 244.739 1.00 51.91  ? 240  SEP A O     1 
ATOM   1848  N N     . ILE A 1 241  ? 210.028 335.508 246.117 1.00 52.69  ? 241  ILE A N     1 
ATOM   1849  C CA    . ILE A 1 241  ? 209.495 336.151 247.309 1.00 52.69  ? 241  ILE A CA    1 
ATOM   1850  C C     . ILE A 1 241  ? 210.284 337.422 247.598 1.00 52.69  ? 241  ILE A C     1 
ATOM   1851  O O     . ILE A 1 241  ? 209.705 338.484 247.808 1.00 52.69  ? 241  ILE A O     1 
ATOM   1852  C CB    . ILE A 1 241  ? 209.522 335.187 248.515 1.00 52.69  ? 241  ILE A CB    1 
ATOM   1853  C CG1   . ILE A 1 241  ? 208.256 334.329 248.546 1.00 52.69  ? 241  ILE A CG1   1 
ATOM   1854  C CG2   . ILE A 1 241  ? 209.670 335.953 249.825 1.00 52.69  ? 241  ILE A CG2   1 
ATOM   1855  C CD1   . ILE A 1 241  ? 206.980 335.127 248.662 1.00 52.69  ? 241  ILE A CD1   1 
ATOM   1856  N N     . LEU A 1 242  ? 211.614 337.301 247.594 1.00 49.70  ? 242  LEU A N     1 
ATOM   1857  C CA    . LEU A 1 242  ? 212.468 338.453 247.862 1.00 49.70  ? 242  LEU A CA    1 
ATOM   1858  C C     . LEU A 1 242  ? 212.289 339.534 246.804 1.00 49.70  ? 242  LEU A C     1 
ATOM   1859  O O     . LEU A 1 242  ? 212.226 340.724 247.128 1.00 49.70  ? 242  LEU A O     1 
ATOM   1860  C CB    . LEU A 1 242  ? 213.930 338.012 247.942 1.00 49.70  ? 242  LEU A CB    1 
ATOM   1861  C CG    . LEU A 1 242  ? 214.927 339.037 248.485 1.00 49.70  ? 242  LEU A CG    1 
ATOM   1862  C CD1   . LEU A 1 242  ? 214.670 339.308 249.960 1.00 49.70  ? 242  LEU A CD1   1 
ATOM   1863  C CD2   . LEU A 1 242  ? 216.354 338.561 248.266 1.00 49.70  ? 242  LEU A CD2   1 
ATOM   1864  N N     . ASN A 1 243  ? 212.200 339.138 245.532 1.00 53.97  ? 243  ASN A N     1 
ATOM   1865  C CA    . ASN A 1 243  ? 212.011 340.114 244.464 1.00 53.97  ? 243  ASN A CA    1 
ATOM   1866  C C     . ASN A 1 243  ? 210.685 340.848 244.616 1.00 53.97  ? 243  ASN A C     1 
ATOM   1867  O O     . ASN A 1 243  ? 210.601 342.055 244.360 1.00 53.97  ? 243  ASN A O     1 
ATOM   1868  C CB    . ASN A 1 243  ? 212.091 339.425 243.102 1.00 53.97  ? 243  ASN A CB    1 
ATOM   1869  C CG    . ASN A 1 243  ? 213.518 339.137 242.678 1.00 53.97  ? 243  ASN A CG    1 
ATOM   1870  O OD1   . ASN A 1 243  ? 214.470 339.631 243.282 1.00 53.97  ? 243  ASN A OD1   1 
ATOM   1871  N ND2   . ASN A 1 243  ? 213.673 338.334 241.632 1.00 53.97  ? 243  ASN A ND2   1 
ATOM   1872  N N     . SER A 1 244  ? 209.638 340.138 245.032 1.00 61.61  ? 244  SER A N     1 
ATOM   1873  C CA    . SER A 1 244  ? 208.328 340.746 245.224 1.00 61.61  ? 244  SER A CA    1 
ATOM   1874  C C     . SER A 1 244  ? 208.159 341.388 246.596 1.00 61.61  ? 244  SER A C     1 
ATOM   1875  O O     . SER A 1 244  ? 207.096 341.959 246.863 1.00 61.61  ? 244  SER A O     1 
ATOM   1876  C CB    . SER A 1 244  ? 207.230 339.701 245.008 1.00 61.61  ? 244  SER A CB    1 
ATOM   1877  O OG    . SER A 1 244  ? 206.749 339.204 246.245 1.00 61.61  ? 244  SER A OG    1 
ATOM   1878  N N     . LEU A 1 245  ? 209.168 341.312 247.470 1.00 59.68  ? 245  LEU A N     1 
ATOM   1879  C CA    . LEU A 1 245  ? 209.047 341.832 248.828 1.00 59.68  ? 245  LEU A CA    1 
ATOM   1880  C C     . LEU A 1 245  ? 210.224 342.736 249.196 1.00 59.68  ? 245  LEU A C     1 
ATOM   1881  O O     . LEU A 1 245  ? 210.358 343.134 250.357 1.00 59.68  ? 245  LEU A O     1 
ATOM   1882  C CB    . LEU A 1 245  ? 208.896 340.668 249.820 1.00 59.68  ? 245  LEU A CB    1 
ATOM   1883  C CG    . LEU A 1 245  ? 208.777 340.809 251.342 1.00 59.68  ? 245  LEU A CG    1 
ATOM   1884  C CD1   . LEU A 1 245  ? 207.689 339.889 251.869 1.00 59.68  ? 245  LEU A CD1   1 
ATOM   1885  C CD2   . LEU A 1 245  ? 210.100 340.489 252.018 1.00 59.68  ? 245  LEU A CD2   1 
ATOM   1886  N N     . LEU A 1 246  ? 211.053 343.123 248.224 1.00 52.73  ? 246  LEU A N     1 
ATOM   1887  C CA    . LEU A 1 246  ? 212.160 344.012 248.562 1.00 52.73  ? 246  LEU A CA    1 
ATOM   1888  C C     . LEU A 1 246  ? 212.108 345.373 247.864 1.00 52.73  ? 246  LEU A C     1 
ATOM   1889  O O     . LEU A 1 246  ? 213.084 345.755 247.205 1.00 52.73  ? 246  LEU A O     1 
ATOM   1890  C CB    . LEU A 1 246  ? 213.494 343.331 248.245 1.00 52.73  ? 246  LEU A CB    1 
ATOM   1891  C CG    . LEU A 1 246  ? 214.720 343.783 249.046 1.00 52.73  ? 246  LEU A CG    1 
ATOM   1892  C CD1   . LEU A 1 246  ? 214.690 343.209 250.452 1.00 52.73  ? 246  LEU A CD1   1 
ATOM   1893  C CD2   . LEU A 1 246  ? 216.004 343.390 248.333 1.00 52.73  ? 246  LEU A CD2   1 
ATOM   1894  N N     . PRO A 1 247  ? 211.011 346.134 247.962 1.00 63.66  ? 247  PRO A N     1 
ATOM   1895  C CA    . PRO A 1 247  ? 211.120 347.588 247.815 1.00 63.66  ? 247  PRO A CA    1 
ATOM   1896  C C     . PRO A 1 247  ? 211.198 348.301 249.154 1.00 63.66  ? 247  PRO A C     1 
ATOM   1897  O O     . PRO A 1 247  ? 211.433 349.518 249.183 1.00 63.66  ? 247  PRO A O     1 
ATOM   1898  C CB    . PRO A 1 247  ? 209.831 347.962 247.063 1.00 63.66  ? 247  PRO A CB    1 
ATOM   1899  C CG    . PRO A 1 247  ? 208.886 346.805 247.267 1.00 63.66  ? 247  PRO A CG    1 
ATOM   1900  C CD    . PRO A 1 247  ? 209.598 345.724 248.029 1.00 63.66  ? 247  PRO A CD    1 
ATOM   1901  N N     . ARG A 1 248  ? 211.009 347.570 250.249 1.00 58.60  ? 248  ARG A N     1 
ATOM   1902  C CA    . ARG A 1 248  ? 211.057 348.099 251.603 1.00 58.60  ? 248  ARG A CA    1 
ATOM   1903  C C     . ARG A 1 248  ? 211.692 347.034 252.491 1.00 58.60  ? 248  ARG A C     1 
ATOM   1904  O O     . ARG A 1 248  ? 212.301 346.076 252.006 1.00 58.60  ? 248  ARG A O     1 
ATOM   1905  C CB    . ARG A 1 248  ? 209.655 348.499 252.082 1.00 58.60  ? 248  ARG A CB    1 
ATOM   1906  C CG    . ARG A 1 248  ? 208.650 347.358 252.070 1.00 58.60  ? 248  ARG A CG    1 
ATOM   1907  C CD    . ARG A 1 248  ? 207.229 347.872 251.906 1.00 58.60  ? 248  ARG A CD    1 
ATOM   1908  N NE    . ARG A 1 248  ? 206.785 348.628 253.071 1.00 58.60  ? 248  ARG A NE    1 
ATOM   1909  C CZ    . ARG A 1 248  ? 205.750 349.456 253.076 1.00 58.60  ? 248  ARG A CZ    1 
ATOM   1910  N NH1   . ARG A 1 248  ? 205.023 349.661 251.990 1.00 58.60  ? 248  ARG A NH1   1 
ATOM   1911  N NH2   . ARG A 1 248  ? 205.436 350.094 254.200 1.00 58.60  ? 248  ARG A NH2   1 
ATOM   1912  N N     . ALA A 1 249  ? 211.549 347.200 253.806 1.00 52.35  ? 249  ALA A N     1 
ATOM   1913  C CA    . ALA A 1 249  ? 212.097 346.220 254.738 1.00 52.35  ? 249  ALA A CA    1 
ATOM   1914  C C     . ALA A 1 249  ? 211.186 345.005 254.865 1.00 52.35  ? 249  ALA A C     1 
ATOM   1915  O O     . ALA A 1 249  ? 211.582 343.879 254.543 1.00 52.35  ? 249  ALA A O     1 
ATOM   1916  C CB    . ALA A 1 249  ? 212.321 346.867 256.106 1.00 52.35  ? 249  ALA A CB    1 
ATOM   1917  N N     . SER A 1 250  ? 209.959 345.215 255.333 1.00 59.29  ? 250  SER A N     1 
ATOM   1918  C CA    . SER A 1 250  ? 208.999 344.135 255.513 1.00 59.29  ? 250  SER A CA    1 
ATOM   1919  C C     . SER A 1 250  ? 207.596 344.708 255.344 1.00 59.29  ? 250  SER A C     1 
ATOM   1920  O O     . SER A 1 250  ? 207.417 345.819 254.836 1.00 59.29  ? 250  SER A O     1 
ATOM   1921  C CB    . SER A 1 250  ? 209.191 343.461 256.878 1.00 59.29  ? 250  SER A CB    1 
ATOM   1922  O OG    . SER A 1 250  ? 208.469 344.141 257.890 1.00 59.29  ? 250  SER A OG    1 
ATOM   1923  N N     . THR A 1 251  ? 206.593 343.937 255.771 1.00 60.39  ? 251  THR A N     1 
ATOM   1924  C CA    . THR A 1 251  ? 205.210 344.389 255.676 1.00 60.39  ? 251  THR A CA    1 
ATOM   1925  C C     . THR A 1 251  ? 204.921 345.575 256.587 1.00 60.39  ? 251  THR A C     1 
ATOM   1926  O O     . THR A 1 251  ? 204.036 346.378 256.275 1.00 60.39  ? 251  THR A O     1 
ATOM   1927  C CB    . THR A 1 251  ? 204.256 343.239 256.007 1.00 60.39  ? 251  THR A CB    1 
ATOM   1928  O OG1   . THR A 1 251  ? 204.798 342.008 255.511 1.00 60.39  ? 251  THR A OG1   1 
ATOM   1929  C CG2   . THR A 1 251  ? 202.893 343.476 255.374 1.00 60.39  ? 251  THR A CG2   1 
ATOM   1930  N N     . SER A 1 252  ? 205.647 345.707 257.697 1.00 59.42  ? 252  SER A N     1 
ATOM   1931  C CA    . SER A 1 252  ? 205.422 346.787 258.650 1.00 59.42  ? 252  SER A CA    1 
ATOM   1932  C C     . SER A 1 252  ? 206.534 347.822 258.680 1.00 59.42  ? 252  SER A C     1 
ATOM   1933  O O     . SER A 1 252  ? 206.267 348.983 258.996 1.00 59.42  ? 252  SER A O     1 
ATOM   1934  C CB    . SER A 1 252  ? 205.238 346.220 260.063 1.00 59.42  ? 252  SER A CB    1 
ATOM   1935  O OG    . SER A 1 252  ? 203.884 345.880 260.305 1.00 59.42  ? 252  SER A OG    1 
ATOM   1936  N N     . LYS A 1 253  ? 207.767 347.438 258.363 1.00 52.67  ? 253  LYS A N     1 
ATOM   1937  C CA    . LYS A 1 253  ? 208.904 348.349 258.378 1.00 52.67  ? 253  LYS A CA    1 
ATOM   1938  C C     . LYS A 1 253  ? 209.130 348.894 256.973 1.00 52.67  ? 253  LYS A C     1 
ATOM   1939  O O     . LYS A 1 253  ? 209.216 348.124 256.011 1.00 52.67  ? 253  LYS A O     1 
ATOM   1940  C CB    . LYS A 1 253  ? 210.162 347.646 258.887 1.00 52.67  ? 253  LYS A CB    1 
ATOM   1941  C CG    . LYS A 1 253  ? 210.107 347.232 260.347 1.00 52.67  ? 253  LYS A CG    1 
ATOM   1942  C CD    . LYS A 1 253  ? 211.448 347.461 261.025 1.00 52.67  ? 253  LYS A CD    1 
ATOM   1943  C CE    . LYS A 1 253  ? 211.689 346.451 262.135 1.00 52.67  ? 253  LYS A CE    1 
ATOM   1944  N NZ    . LYS A 1 253  ? 210.460 346.211 262.938 1.00 52.67  ? 253  LYS A NZ    1 
ATOM   1945  N N     . GLU A 1 254  ? 209.223 350.222 256.860 1.00 52.57  ? 254  GLU A N     1 
ATOM   1946  C CA    . GLU A 1 254  ? 209.458 350.834 255.557 1.00 52.57  ? 254  GLU A CA    1 
ATOM   1947  C C     . GLU A 1 254  ? 210.907 350.680 255.111 1.00 52.57  ? 254  GLU A C     1 
ATOM   1948  O O     . GLU A 1 254  ? 211.182 350.661 253.906 1.00 52.57  ? 254  GLU A O     1 
ATOM   1949  C CB    . GLU A 1 254  ? 209.062 352.311 255.590 1.00 52.57  ? 254  GLU A CB    1 
ATOM   1950  C CG    . GLU A 1 254  ? 209.926 353.174 256.495 1.00 52.57  ? 254  GLU A CG    1 
ATOM   1951  C CD    . GLU A 1 254  ? 209.198 354.409 256.989 1.00 52.57  ? 254  GLU A CD    1 
ATOM   1952  O OE1   . GLU A 1 254  ? 209.028 355.358 256.195 1.00 52.57  ? 254  GLU A OE1   1 
ATOM   1953  O OE2   . GLU A 1 254  ? 208.797 354.431 258.171 1.00 52.57  ? 254  GLU A OE2   1 
ATOM   1954  N N     . VAL A 1 255  ? 211.839 350.571 256.054 1.00 51.03  ? 255  VAL A N     1 
ATOM   1955  C CA    . VAL A 1 255  ? 213.253 350.418 255.726 1.00 51.03  ? 255  VAL A CA    1 
ATOM   1956  C C     . VAL A 1 255  ? 213.963 349.835 256.940 1.00 51.03  ? 255  VAL A C     1 
ATOM   1957  O O     . VAL A 1 255  ? 213.630 350.153 258.085 1.00 51.03  ? 255  VAL A O     1 
ATOM   1958  C CB    . VAL A 1 255  ? 213.875 351.764 255.278 1.00 51.03  ? 255  VAL A CB    1 
ATOM   1959  C CG1   . VAL A 1 255  ? 213.860 352.777 256.415 1.00 51.03  ? 255  VAL A CG1   1 
ATOM   1960  C CG2   . VAL A 1 255  ? 215.289 351.555 254.752 1.00 51.03  ? 255  VAL A CG2   1 
ATOM   1961  N N     . ASP A 1 256  ? 214.931 348.959 256.679 1.00 44.43  ? 256  ASP A N     1 
ATOM   1962  C CA    . ASP A 1 256  ? 215.743 348.351 257.722 1.00 44.43  ? 256  ASP A CA    1 
ATOM   1963  C C     . ASP A 1 256  ? 217.202 348.384 257.296 1.00 44.43  ? 256  ASP A C     1 
ATOM   1964  O O     . ASP A 1 256  ? 217.521 348.126 256.132 1.00 44.43  ? 256  ASP A O     1 
ATOM   1965  C CB    . ASP A 1 256  ? 215.314 346.905 258.003 1.00 44.43  ? 256  ASP A CB    1 
ATOM   1966  C CG    . ASP A 1 256  ? 215.522 346.504 259.451 1.00 44.43  ? 256  ASP A CG    1 
ATOM   1967  O OD1   . ASP A 1 256  ? 215.852 347.383 260.273 1.00 44.43  ? 256  ASP A OD1   1 
ATOM   1968  O OD2   . ASP A 1 256  ? 215.353 345.307 259.767 1.00 44.43  ? 256  ASP A OD2   1 
ATOM   1969  N N     . ALA A 1 257  ? 218.084 348.703 258.244 1.00 40.53  ? 257  ALA A N     1 
ATOM   1970  C CA    . ALA A 1 257  ? 219.511 348.716 257.956 1.00 40.53  ? 257  ALA A CA    1 
ATOM   1971  C C     . ALA A 1 257  ? 220.097 347.318 257.822 1.00 40.53  ? 257  ALA A C     1 
ATOM   1972  O O     . ALA A 1 257  ? 221.231 347.184 257.351 1.00 40.53  ? 257  ALA A O     1 
ATOM   1973  C CB    . ALA A 1 257  ? 220.259 349.490 259.041 1.00 40.53  ? 257  ALA A CB    1 
ATOM   1974  N N     . SER A 1 258  ? 219.359 346.281 258.224 1.00 36.73  ? 258  SER A N     1 
ATOM   1975  C CA    . SER A 1 258  ? 219.835 344.915 258.046 1.00 36.73  ? 258  SER A CA    1 
ATOM   1976  C C     . SER A 1 258  ? 219.715 344.447 256.602 1.00 36.73  ? 258  SER A C     1 
ATOM   1977  O O     . SER A 1 258  ? 220.219 343.369 256.270 1.00 36.73  ? 258  SER A O     1 
ATOM   1978  C CB    . SER A 1 258  ? 219.069 343.962 258.963 1.00 36.73  ? 258  SER A CB    1 
ATOM   1979  O OG    . SER A 1 258  ? 219.189 342.625 258.510 1.00 36.73  ? 258  SER A OG    1 
ATOM   1980  N N     . LEU A 1 259  ? 219.056 345.228 255.741 1.00 37.04  ? 259  LEU A N     1 
ATOM   1981  C CA    . LEU A 1 259  ? 218.940 344.860 254.335 1.00 37.04  ? 259  LEU A CA    1 
ATOM   1982  C C     . LEU A 1 259  ? 220.290 344.847 253.631 1.00 37.04  ? 259  LEU A C     1 
ATOM   1983  O O     . LEU A 1 259  ? 220.412 344.234 252.564 1.00 37.04  ? 259  LEU A O     1 
ATOM   1984  C CB    . LEU A 1 259  ? 217.985 345.815 253.617 1.00 37.04  ? 259  LEU A CB    1 
ATOM   1985  C CG    . LEU A 1 259  ? 216.552 345.318 253.409 1.00 37.04  ? 259  LEU A CG    1 
ATOM   1986  C CD1   . LEU A 1 259  ? 215.855 345.092 254.742 1.00 37.04  ? 259  LEU A CD1   1 
ATOM   1987  C CD2   . LEU A 1 259  ? 215.765 346.294 252.547 1.00 37.04  ? 259  LEU A CD2   1 
ATOM   1988  N N     . LEU A 1 260  ? 221.301 345.511 254.198 1.00 35.44  ? 260  LEU A N     1 
ATOM   1989  C CA    . LEU A 1 260  ? 222.642 345.442 253.629 1.00 35.44  ? 260  LEU A CA    1 
ATOM   1990  C C     . LEU A 1 260  ? 223.192 344.024 253.669 1.00 35.44  ? 260  LEU A C     1 
ATOM   1991  O O     . LEU A 1 260  ? 223.890 343.603 252.740 1.00 35.44  ? 260  LEU A O     1 
ATOM   1992  C CB    . LEU A 1 260  ? 223.583 346.392 254.370 1.00 35.44  ? 260  LEU A CB    1 
ATOM   1993  C CG    . LEU A 1 260  ? 223.563 347.860 253.944 1.00 35.44  ? 260  LEU A CG    1 
ATOM   1994  C CD1   . LEU A 1 260  ? 222.487 348.623 254.697 1.00 35.44  ? 260  LEU A CD1   1 
ATOM   1995  C CD2   . LEU A 1 260  ? 224.927 348.495 254.160 1.00 35.44  ? 260  LEU A CD2   1 
ATOM   1996  N N     . SER A 1 261  ? 222.880 343.270 254.725 1.00 35.87  ? 261  SER A N     1 
ATOM   1997  C CA    . SER A 1 261  ? 223.364 341.901 254.860 1.00 35.87  ? 261  SER A CA    1 
ATOM   1998  C C     . SER A 1 261  ? 222.816 340.963 253.791 1.00 35.87  ? 261  SER A C     1 
ATOM   1999  O O     . SER A 1 261  ? 223.160 339.777 253.801 1.00 35.87  ? 261  SER A O     1 
ATOM   2000  C CB    . SER A 1 261  ? 223.014 341.358 256.248 1.00 35.87  ? 261  SER A CB    1 
ATOM   2001  O OG    . SER A 1 261  ? 221.836 340.571 256.206 1.00 35.87  ? 261  SER A OG    1 
ATOM   2002  N N     . VAL A 1 262  ? 221.971 341.455 252.887 1.00 35.64  ? 262  VAL A N     1 
ATOM   2003  C CA    . VAL A 1 262  ? 221.410 340.639 251.817 1.00 35.64  ? 262  VAL A CA    1 
ATOM   2004  C C     . VAL A 1 262  ? 221.995 341.097 250.485 1.00 35.64  ? 262  VAL A C     1 
ATOM   2005  O O     . VAL A 1 262  ? 222.141 340.303 249.548 1.00 35.64  ? 262  VAL A O     1 
ATOM   2006  C CB    . VAL A 1 262  ? 219.871 340.722 251.823 1.00 35.64  ? 262  VAL A CB    1 
ATOM   2007  C CG1   . VAL A 1 262  ? 219.275 340.092 250.572 1.00 35.64  ? 262  VAL A CG1   1 
ATOM   2008  C CG2   . VAL A 1 262  ? 219.315 340.060 253.072 1.00 35.64  ? 262  VAL A CG2   1 
ATOM   2009  N N     . VAL A 1 263  ? 222.371 342.373 250.407 1.00 38.16  ? 263  VAL A N     1 
ATOM   2010  C CA    . VAL A 1 263  ? 222.792 342.980 249.148 1.00 38.16  ? 263  VAL A CA    1 
ATOM   2011  C C     . VAL A 1 263  ? 224.256 343.398 249.211 1.00 38.16  ? 263  VAL A C     1 
ATOM   2012  O O     . VAL A 1 263  ? 224.666 344.364 248.558 1.00 38.16  ? 263  VAL A O     1 
ATOM   2013  C CB    . VAL A 1 263  ? 221.891 344.178 248.794 1.00 38.16  ? 263  VAL A CB    1 
ATOM   2014  C CG1   . VAL A 1 263  ? 220.454 343.722 248.607 1.00 38.16  ? 263  VAL A CG1   1 
ATOM   2015  C CG2   . VAL A 1 263  ? 221.970 345.246 249.877 1.00 38.16  ? 263  VAL A CG2   1 
ATOM   2016  N N     . SER A 1 264  ? 225.057 342.666 249.975 1.00 41.08  ? 264  SER A N     1 
ATOM   2017  C CA    . SER A 1 264  ? 226.468 342.999 250.152 1.00 41.08  ? 264  SER A CA    1 
ATOM   2018  C C     . SER A 1 264  ? 227.248 341.698 250.313 1.00 41.08  ? 264  SER A C     1 
ATOM   2019  O O     . SER A 1 264  ? 226.770 340.623 249.935 1.00 41.08  ? 264  SER A O     1 
ATOM   2020  C CB    . SER A 1 264  ? 226.657 343.958 251.341 1.00 41.08  ? 264  SER A CB    1 
ATOM   2021  O OG    . SER A 1 264  ? 225.747 345.042 251.279 1.00 41.08  ? 264  SER A OG    1 
ATOM   2022  N N     . PHE A 1 265  ? 228.461 341.802 250.858 1.00 44.39  ? 265  PHE A N     1 
ATOM   2023  C CA    . PHE A 1 265  ? 229.337 340.644 251.036 1.00 44.39  ? 265  PHE A CA    1 
ATOM   2024  C C     . PHE A 1 265  ? 228.678 339.465 251.747 1.00 44.39  ? 265  PHE A C     1 
ATOM   2025  O O     . PHE A 1 265  ? 228.847 338.328 251.278 1.00 44.39  ? 265  PHE A O     1 
ATOM   2026  C CB    . PHE A 1 265  ? 230.610 341.089 251.774 1.00 44.39  ? 265  PHE A CB    1 
ATOM   2027  C CG    . PHE A 1 265  ? 231.163 340.058 252.722 1.00 44.39  ? 265  PHE A CG    1 
ATOM   2028  C CD1   . PHE A 1 265  ? 231.825 338.936 252.246 1.00 44.39  ? 265  PHE A CD1   1 
ATOM   2029  C CD2   . PHE A 1 265  ? 231.031 340.217 254.093 1.00 44.39  ? 265  PHE A CD2   1 
ATOM   2030  C CE1   . PHE A 1 265  ? 232.335 337.991 253.116 1.00 44.39  ? 265  PHE A CE1   1 
ATOM   2031  C CE2   . PHE A 1 265  ? 231.539 339.274 254.968 1.00 44.39  ? 265  PHE A CE2   1 
ATOM   2032  C CZ    . PHE A 1 265  ? 232.192 338.161 254.479 1.00 44.39  ? 265  PHE A CZ    1 
ATOM   2033  N N     . PRO A 1 266  ? 227.941 339.635 252.849 1.00 43.06  ? 266  PRO A N     1 
ATOM   2034  C CA    . PRO A 1 266  ? 227.363 338.452 253.509 1.00 43.06  ? 266  PRO A CA    1 
ATOM   2035  C C     . PRO A 1 266  ? 226.255 337.831 252.669 1.00 43.06  ? 266  PRO A C     1 
ATOM   2036  O O     . PRO A 1 266  ? 225.196 338.430 252.467 1.00 43.06  ? 266  PRO A O     1 
ATOM   2037  C CB    . PRO A 1 266  ? 226.825 339.008 254.834 1.00 43.06  ? 266  PRO A CB    1 
ATOM   2038  C CG    . PRO A 1 266  ? 226.618 340.443 254.598 1.00 43.06  ? 266  PRO A CG    1 
ATOM   2039  C CD    . PRO A 1 266  ? 227.632 340.875 253.588 1.00 43.06  ? 266  PRO A CD    1 
ATOM   2040  N N     . ALA A 1 267  ? 226.523 336.630 252.159 1.00 38.89  ? 267  ALA A N     1 
ATOM   2041  C CA    . ALA A 1 267  ? 225.622 335.695 251.495 1.00 38.89  ? 267  ALA A CA    1 
ATOM   2042  C C     . ALA A 1 267  ? 225.248 336.108 250.071 1.00 38.89  ? 267  ALA A C     1 
ATOM   2043  O O     . ALA A 1 267  ? 224.724 335.271 249.335 1.00 38.89  ? 267  ALA A O     1 
ATOM   2044  C CB    . ALA A 1 267  ? 224.322 335.452 252.286 1.00 38.89  ? 267  ALA A CB    1 
ATOM   2045  N N     . PHE A 1 268  ? 225.526 337.344 249.645 1.00 41.13  ? 268  PHE A N     1 
ATOM   2046  C CA    . PHE A 1 268  ? 225.287 337.812 248.280 1.00 41.13  ? 268  PHE A CA    1 
ATOM   2047  C C     . PHE A 1 268  ? 223.975 337.311 247.684 1.00 41.13  ? 268  PHE A C     1 
ATOM   2048  O O     . PHE A 1 268  ? 223.933 336.916 246.514 1.00 41.13  ? 268  PHE A O     1 
ATOM   2049  C CB    . PHE A 1 268  ? 226.450 337.402 247.374 1.00 41.13  ? 268  PHE A CB    1 
ATOM   2050  C CG    . PHE A 1 268  ? 227.600 338.365 247.396 1.00 41.13  ? 268  PHE A CG    1 
ATOM   2051  C CD1   . PHE A 1 268  ? 227.458 339.643 246.883 1.00 41.13  ? 268  PHE A CD1   1 
ATOM   2052  C CD2   . PHE A 1 268  ? 228.822 337.994 247.931 1.00 41.13  ? 268  PHE A CD2   1 
ATOM   2053  C CE1   . PHE A 1 268  ? 228.513 340.534 246.901 1.00 41.13  ? 268  PHE A CE1   1 
ATOM   2054  C CE2   . PHE A 1 268  ? 229.881 338.880 247.952 1.00 41.13  ? 268  PHE A CE2   1 
ATOM   2055  C CZ    . PHE A 1 268  ? 229.725 340.152 247.436 1.00 41.13  ? 268  PHE A CZ    1 
ATOM   2056  N N     . ALA A 1 269  ? 222.901 337.318 248.473 1.00 41.03  ? 269  ALA A N     1 
ATOM   2057  C CA    . ALA A 1 269  ? 221.634 336.716 248.052 1.00 41.03  ? 269  ALA A CA    1 
ATOM   2058  C C     . ALA A 1 269  ? 220.716 337.785 247.457 1.00 41.03  ? 269  ALA A C     1 
ATOM   2059  O O     . ALA A 1 269  ? 219.685 338.159 248.019 1.00 41.03  ? 269  ALA A O     1 
ATOM   2060  C CB    . ALA A 1 269  ? 220.974 335.999 249.221 1.00 41.03  ? 269  ALA A CB    1 
ATOM   2061  N N     . VAL A 1 270  ? 221.110 338.267 246.279 1.00 48.97  ? 270  VAL A N     1 
ATOM   2062  C CA    . VAL A 1 270  ? 220.335 339.283 245.574 1.00 48.97  ? 270  VAL A CA    1 
ATOM   2063  C C     . VAL A 1 270  ? 220.764 339.341 244.112 1.00 48.97  ? 270  VAL A C     1 
ATOM   2064  O O     . VAL A 1 270  ? 221.921 339.060 243.777 1.00 48.97  ? 270  VAL A O     1 
ATOM   2065  C CB    . VAL A 1 270  ? 220.480 340.659 246.254 1.00 48.97  ? 270  VAL A CB    1 
ATOM   2066  C CG1   . VAL A 1 270  ? 221.880 341.220 246.047 1.00 48.97  ? 270  VAL A CG1   1 
ATOM   2067  C CG2   . VAL A 1 270  ? 219.415 341.627 245.751 1.00 48.97  ? 270  VAL A CG2   1 
ATOM   2068  N N     . GLU A 1 271  ? 219.825 339.687 243.232 1.00 59.23  ? 271  GLU A N     1 
ATOM   2069  C CA    . GLU A 1 271  ? 220.122 339.926 241.826 1.00 59.23  ? 271  GLU A CA    1 
ATOM   2070  C C     . GLU A 1 271  ? 219.594 341.298 241.429 1.00 59.23  ? 271  GLU A C     1 
ATOM   2071  O O     . GLU A 1 271  ? 219.132 342.055 242.290 1.00 59.23  ? 271  GLU A O     1 
ATOM   2072  C CB    . GLU A 1 271  ? 219.512 338.834 240.946 1.00 59.23  ? 271  GLU A CB    1 
ATOM   2073  C CG    . GLU A 1 271  ? 220.180 337.475 241.086 1.00 59.23  ? 271  GLU A CG    1 
ATOM   2074  C CD    . GLU A 1 271  ? 219.532 336.415 240.218 1.00 59.23  ? 271  GLU A CD    1 
ATOM   2075  O OE1   . GLU A 1 271  ? 218.500 336.715 239.581 1.00 59.23  ? 271  GLU A OE1   1 
ATOM   2076  O OE2   . GLU A 1 271  ? 220.054 335.281 240.171 1.00 59.23  ? 271  GLU A OE2   1 
ATOM   2077  N N     . ASP A 1 272  ? 219.655 341.628 240.136 1.00 64.99  ? 272  ASP A N     1 
ATOM   2078  C CA    . ASP A 1 272  ? 219.148 342.897 239.613 1.00 64.99  ? 272  ASP A CA    1 
ATOM   2079  C C     . ASP A 1 272  ? 219.827 344.080 240.312 1.00 64.99  ? 272  ASP A C     1 
ATOM   2080  O O     . ASP A 1 272  ? 219.216 344.830 241.075 1.00 64.99  ? 272  ASP A O     1 
ATOM   2081  C CB    . ASP A 1 272  ? 217.621 342.972 239.742 1.00 64.99  ? 272  ASP A CB    1 
ATOM   2082  C CG    . ASP A 1 272  ? 216.985 343.816 238.654 1.00 64.99  ? 272  ASP A CG    1 
ATOM   2083  O OD1   . ASP A 1 272  ? 217.531 344.894 238.339 1.00 64.99  ? 272  ASP A OD1   1 
ATOM   2084  O OD2   . ASP A 1 272  ? 215.938 343.400 238.114 1.00 64.99  ? 272  ASP A OD2   1 
ATOM   2085  N N     . SER A 1 273  ? 221.128 344.204 240.036 1.00 67.12  ? 273  SER A N     1 
ATOM   2086  C CA    . SER A 1 273  ? 222.007 345.194 240.656 1.00 67.12  ? 273  SER A CA    1 
ATOM   2087  C C     . SER A 1 273  ? 221.394 346.590 240.724 1.00 67.12  ? 273  SER A C     1 
ATOM   2088  O O     . SER A 1 273  ? 221.729 347.374 241.619 1.00 67.12  ? 273  SER A O     1 
ATOM   2089  C CB    . SER A 1 273  ? 223.338 345.253 239.903 1.00 67.12  ? 273  SER A CB    1 
ATOM   2090  O OG    . SER A 1 273  ? 224.256 346.112 240.557 1.00 67.12  ? 273  SER A OG    1 
ATOM   2091  N N     . GLN A 1 274  ? 220.506 346.916 239.781 1.00 68.26  ? 274  GLN A N     1 
ATOM   2092  C CA    . GLN A 1 274  ? 219.786 348.184 239.857 1.00 68.26  ? 274  GLN A CA    1 
ATOM   2093  C C     . GLN A 1 274  ? 218.952 348.264 241.129 1.00 68.26  ? 274  GLN A C     1 
ATOM   2094  O O     . GLN A 1 274  ? 218.928 349.301 241.802 1.00 68.26  ? 274  GLN A O     1 
ATOM   2095  C CB    . GLN A 1 274  ? 218.902 348.362 238.622 1.00 68.26  ? 274  GLN A CB    1 
ATOM   2096  C CG    . GLN A 1 274  ? 219.649 348.280 237.299 1.00 68.26  ? 274  GLN A CG    1 
ATOM   2097  C CD    . GLN A 1 274  ? 220.672 349.388 237.131 1.00 68.26  ? 274  GLN A CD    1 
ATOM   2098  O OE1   . GLN A 1 274  ? 220.548 350.460 237.722 1.00 68.26  ? 274  GLN A OE1   1 
ATOM   2099  N NE2   . GLN A 1 274  ? 221.691 349.132 236.319 1.00 68.26  ? 274  GLN A NE2   1 
ATOM   2100  N N     . LEU A 1 275  ? 218.267 347.172 241.480 1.00 57.89  ? 275  LEU A N     1 
ATOM   2101  C CA    . LEU A 1 275  ? 217.517 347.136 242.731 1.00 57.89  ? 275  LEU A CA    1 
ATOM   2102  C C     . LEU A 1 275  ? 218.446 347.260 243.933 1.00 57.89  ? 275  LEU A C     1 
ATOM   2103  O O     . LEU A 1 275  ? 218.095 347.892 244.936 1.00 57.89  ? 275  LEU A O     1 
ATOM   2104  C CB    . LEU A 1 275  ? 216.692 345.849 242.810 1.00 57.89  ? 275  LEU A CB    1 
ATOM   2105  C CG    . LEU A 1 275  ? 216.025 345.495 244.142 1.00 57.89  ? 275  LEU A CG    1 
ATOM   2106  C CD1   . LEU A 1 275  ? 214.606 345.006 243.910 1.00 57.89  ? 275  LEU A CD1   1 
ATOM   2107  C CD2   . LEU A 1 275  ? 216.833 344.440 244.886 1.00 57.89  ? 275  LEU A CD2   1 
ATOM   2108  N N     . VAL A 1 276  ? 219.636 346.659 243.849 1.00 52.92  ? 276  VAL A N     1 
ATOM   2109  C CA    . VAL A 1 276  ? 220.605 346.761 244.938 1.00 52.92  ? 276  VAL A CA    1 
ATOM   2110  C C     . VAL A 1 276  ? 221.009 348.215 245.153 1.00 52.92  ? 276  VAL A C     1 
ATOM   2111  O O     . VAL A 1 276  ? 221.016 348.719 246.283 1.00 52.92  ? 276  VAL A O     1 
ATOM   2112  C CB    . VAL A 1 276  ? 221.830 345.876 244.645 1.00 52.92  ? 276  VAL A CB    1 
ATOM   2113  C CG1   . VAL A 1 276  ? 222.835 345.962 245.781 1.00 52.92  ? 276  VAL A CG1   1 
ATOM   2114  C CG2   . VAL A 1 276  ? 221.401 344.439 244.404 1.00 52.92  ? 276  VAL A CG2   1 
ATOM   2115  N N     . GLU A 1 277  ? 221.347 348.910 244.064 1.00 57.06  ? 277  GLU A N     1 
ATOM   2116  C CA    . GLU A 1 277  ? 221.723 350.316 244.168 1.00 57.06  ? 277  GLU A CA    1 
ATOM   2117  C C     . GLU A 1 277  ? 220.561 351.160 244.676 1.00 57.06  ? 277  GLU A C     1 
ATOM   2118  O O     . GLU A 1 277  ? 220.755 352.074 245.486 1.00 57.06  ? 277  GLU A O     1 
ATOM   2119  C CB    . GLU A 1 277  ? 222.210 350.832 242.813 1.00 57.06  ? 277  GLU A CB    1 
ATOM   2120  C CG    . GLU A 1 277  ? 223.465 350.144 242.300 1.00 57.06  ? 277  GLU A CG    1 
ATOM   2121  C CD    . GLU A 1 277  ? 224.680 350.424 243.164 1.00 57.06  ? 277  GLU A CD    1 
ATOM   2122  O OE1   . GLU A 1 277  ? 224.760 351.529 243.740 1.00 57.06  ? 277  GLU A OE1   1 
ATOM   2123  O OE2   . GLU A 1 277  ? 225.554 349.538 243.267 1.00 57.06  ? 277  GLU A OE2   1 
ATOM   2124  N N     . LEU A 1 278  ? 219.344 350.863 244.213 1.00 56.87  ? 278  LEU A N     1 
ATOM   2125  C CA    . LEU A 1 278  ? 218.171 351.607 244.658 1.00 56.87  ? 278  LEU A CA    1 
ATOM   2126  C C     . LEU A 1 278  ? 217.972 351.458 246.163 1.00 56.87  ? 278  LEU A C     1 
ATOM   2127  O O     . LEU A 1 278  ? 217.788 352.449 246.884 1.00 56.87  ? 278  LEU A O     1 
ATOM   2128  C CB    . LEU A 1 278  ? 216.940 351.110 243.896 1.00 56.87  ? 278  LEU A CB    1 
ATOM   2129  C CG    . LEU A 1 278  ? 215.582 351.777 244.111 1.00 56.87  ? 278  LEU A CG    1 
ATOM   2130  C CD1   . LEU A 1 278  ? 215.587 353.170 243.502 1.00 56.87  ? 278  LEU A CD1   1 
ATOM   2131  C CD2   . LEU A 1 278  ? 214.463 350.931 243.524 1.00 56.87  ? 278  LEU A CD2   1 
ATOM   2132  N N     . THR A 1 279  ? 218.026 350.216 246.656 1.00 51.97  ? 279  THR A N     1 
ATOM   2133  C CA    . THR A 1 279  ? 217.833 349.962 248.079 1.00 51.97  ? 279  THR A CA    1 
ATOM   2134  C C     . THR A 1 279  ? 218.938 350.600 248.909 1.00 51.97  ? 279  THR A C     1 
ATOM   2135  O O     . THR A 1 279  ? 218.676 351.148 249.986 1.00 51.97  ? 279  THR A O     1 
ATOM   2136  C CB    . THR A 1 279  ? 217.769 348.458 248.343 1.00 51.97  ? 279  THR A CB    1 
ATOM   2137  O OG1   . THR A 1 279  ? 218.762 347.790 247.554 1.00 51.97  ? 279  THR A OG1   1 
ATOM   2138  C CG2   . THR A 1 279  ? 216.394 347.912 247.987 1.00 51.97  ? 279  THR A CG2   1 
ATOM   2139  N N     . LYS A 1 280  ? 220.183 350.538 248.427 1.00 46.36  ? 280  LYS A N     1 
ATOM   2140  C CA    . LYS A 1 280  ? 221.274 351.196 249.138 1.00 46.36  ? 280  LYS A CA    1 
ATOM   2141  C C     . LYS A 1 280  ? 221.061 352.704 249.192 1.00 46.36  ? 280  LYS A C     1 
ATOM   2142  O O     . LYS A 1 280  ? 221.348 353.343 250.212 1.00 46.36  ? 280  LYS A O     1 
ATOM   2143  C CB    . LYS A 1 280  ? 222.611 350.862 248.479 1.00 46.36  ? 280  LYS A CB    1 
ATOM   2144  C CG    . LYS A 1 280  ? 223.060 349.424 248.688 1.00 46.36  ? 280  LYS A CG    1 
ATOM   2145  C CD    . LYS A 1 280  ? 224.368 349.141 247.970 1.00 46.36  ? 280  LYS A CD    1 
ATOM   2146  C CE    . LYS A 1 280  ? 224.885 347.750 248.298 1.00 46.36  ? 280  LYS A CE    1 
ATOM   2147  N NZ    . LYS A 1 280  ? 225.346 347.649 249.710 1.00 46.36  ? 280  LYS A NZ    1 
ATOM   2148  N N     . GLN A 1 281  ? 220.555 353.290 248.103 1.00 47.66  ? 281  GLN A N     1 
ATOM   2149  C CA    . GLN A 1 281  ? 220.291 354.724 248.092 1.00 47.66  ? 281  GLN A CA    1 
ATOM   2150  C C     . GLN A 1 281  ? 219.225 355.101 249.114 1.00 47.66  ? 281  GLN A C     1 
ATOM   2151  O O     . GLN A 1 281  ? 219.388 356.079 249.854 1.00 47.66  ? 281  GLN A O     1 
ATOM   2152  C CB    . GLN A 1 281  ? 219.875 355.170 246.690 1.00 47.66  ? 281  GLN A CB    1 
ATOM   2153  C CG    . GLN A 1 281  ? 220.075 356.653 246.430 1.00 47.66  ? 281  GLN A CG    1 
ATOM   2154  C CD    . GLN A 1 281  ? 221.541 357.038 246.357 1.00 47.66  ? 281  GLN A CD    1 
ATOM   2155  O OE1   . GLN A 1 281  ? 222.341 356.361 245.711 1.00 47.66  ? 281  GLN A OE1   1 
ATOM   2156  N NE2   . GLN A 1 281  ? 221.900 358.129 247.023 1.00 47.66  ? 281  GLN A NE2   1 
ATOM   2157  N N     . GLU A 1 282  ? 218.128 354.339 249.175 1.00 46.84  ? 282  GLU A N     1 
ATOM   2158  C CA    . GLU A 1 282  ? 217.109 354.636 250.185 1.00 46.84  ? 282  GLU A CA    1 
ATOM   2159  C C     . GLU A 1 282  ? 217.640 354.428 251.598 1.00 46.84  ? 282  GLU A C     1 
ATOM   2160  O O     . GLU A 1 282  ? 217.308 355.197 252.508 1.00 46.84  ? 282  GLU A O     1 
ATOM   2161  C CB    . GLU A 1 282  ? 215.836 353.811 249.968 1.00 46.84  ? 282  GLU A CB    1 
ATOM   2162  C CG    . GLU A 1 282  ? 215.535 353.383 248.547 1.00 46.84  ? 282  GLU A CG    1 
ATOM   2163  C CD    . GLU A 1 282  ? 215.450 354.546 247.565 1.00 46.84  ? 282  GLU A CD    1 
ATOM   2164  O OE1   . GLU A 1 282  ? 215.384 355.718 247.995 1.00 46.84  ? 282  GLU A OE1   1 
ATOM   2165  O OE2   . GLU A 1 282  ? 215.449 354.284 246.349 1.00 46.84  ? 282  GLU A OE2   1 
ATOM   2166  N N     . ILE A 1 283  ? 218.455 353.392 251.809 1.00 42.85  ? 283  ILE A N     1 
ATOM   2167  C CA    . ILE A 1 283  ? 219.017 353.153 253.136 1.00 42.85  ? 283  ILE A CA    1 
ATOM   2168  C C     . ILE A 1 283  ? 219.889 354.330 253.558 1.00 42.85  ? 283  ILE A C     1 
ATOM   2169  O O     . ILE A 1 283  ? 219.798 354.821 254.690 1.00 42.85  ? 283  ILE A O     1 
ATOM   2170  C CB    . ILE A 1 283  ? 219.801 351.828 253.156 1.00 42.85  ? 283  ILE A CB    1 
ATOM   2171  C CG1   . ILE A 1 283  ? 218.841 350.644 253.278 1.00 42.85  ? 283  ILE A CG1   1 
ATOM   2172  C CG2   . ILE A 1 283  ? 220.806 351.819 254.297 1.00 42.85  ? 283  ILE A CG2   1 
ATOM   2173  C CD1   . ILE A 1 283  ? 219.390 349.352 252.715 1.00 42.85  ? 283  ILE A CD1   1 
ATOM   2174  N N     . ILE A 1 284  ? 220.735 354.811 252.644 1.00 38.37  ? 284  ILE A N     1 
ATOM   2175  C CA    . ILE A 1 284  ? 221.589 355.956 252.945 1.00 38.37  ? 284  ILE A CA    1 
ATOM   2176  C C     . ILE A 1 284  ? 220.745 357.194 253.225 1.00 38.37  ? 284  ILE A C     1 
ATOM   2177  O O     . ILE A 1 284  ? 221.011 357.943 254.173 1.00 38.37  ? 284  ILE A O     1 
ATOM   2178  C CB    . ILE A 1 284  ? 222.583 356.195 251.793 1.00 38.37  ? 284  ILE A CB    1 
ATOM   2179  C CG1   . ILE A 1 284  ? 223.671 355.118 251.797 1.00 38.37  ? 284  ILE A CG1   1 
ATOM   2180  C CG2   . ILE A 1 284  ? 223.194 357.589 251.888 1.00 38.37  ? 284  ILE A CG2   1 
ATOM   2181  C CD1   . ILE A 1 284  ? 224.935 355.509 251.058 1.00 38.37  ? 284  ILE A CD1   1 
ATOM   2182  N N     . THR A 1 285  ? 219.713 357.425 252.412 1.00 41.46  ? 285  THR A N     1 
ATOM   2183  C CA    . THR A 1 285  ? 218.894 358.622 252.576 1.00 41.46  ? 285  THR A CA    1 
ATOM   2184  C C     . THR A 1 285  ? 218.135 358.611 253.898 1.00 41.46  ? 285  THR A C     1 
ATOM   2185  O O     . THR A 1 285  ? 218.013 359.651 254.557 1.00 41.46  ? 285  THR A O     1 
ATOM   2186  C CB    . THR A 1 285  ? 217.921 358.755 251.404 1.00 41.46  ? 285  THR A CB    1 
ATOM   2187  O OG1   . THR A 1 285  ? 218.624 358.558 250.171 1.00 41.46  ? 285  THR A OG1   1 
ATOM   2188  C CG2   . THR A 1 285  ? 217.279 360.135 251.398 1.00 41.46  ? 285  THR A CG2   1 
ATOM   2189  N N     . LYS A 1 286  ? 217.620 357.451 254.308 1.00 40.84  ? 286  LYS A N     1 
ATOM   2190  C CA    . LYS A 1 286  ? 216.707 357.379 255.440 1.00 40.84  ? 286  LYS A CA    1 
ATOM   2191  C C     . LYS A 1 286  ? 217.363 356.954 256.748 1.00 40.84  ? 286  LYS A C     1 
ATOM   2192  O O     . LYS A 1 286  ? 216.707 357.020 257.793 1.00 40.84  ? 286  LYS A O     1 
ATOM   2193  C CB    . LYS A 1 286  ? 215.556 356.415 255.123 1.00 40.84  ? 286  LYS A CB    1 
ATOM   2194  C CG    . LYS A 1 286  ? 214.486 356.999 254.214 1.00 40.84  ? 286  LYS A CG    1 
ATOM   2195  C CD    . LYS A 1 286  ? 213.488 355.936 253.785 1.00 40.84  ? 286  LYS A CD    1 
ATOM   2196  C CE    . LYS A 1 286  ? 212.290 356.554 253.082 1.00 40.84  ? 286  LYS A CE    1 
ATOM   2197  N NZ    . LYS A 1 286  ? 211.291 355.526 252.680 1.00 40.84  ? 286  LYS A NZ    1 
ATOM   2198  N N     . LEU A 1 287  ? 218.626 356.522 256.734 1.00 39.60  ? 287  LEU A N     1 
ATOM   2199  C CA    . LEU A 1 287  ? 219.249 355.997 257.944 1.00 39.60  ? 287  LEU A CA    1 
ATOM   2200  C C     . LEU A 1 287  ? 220.623 356.569 258.263 1.00 39.60  ? 287  LEU A C     1 
ATOM   2201  O O     . LEU A 1 287  ? 221.033 356.496 259.427 1.00 39.60  ? 287  LEU A O     1 
ATOM   2202  C CB    . LEU A 1 287  ? 219.367 354.467 257.865 1.00 39.60  ? 287  LEU A CB    1 
ATOM   2203  C CG    . LEU A 1 287  ? 218.059 353.689 257.703 1.00 39.60  ? 287  LEU A CG    1 
ATOM   2204  C CD1   . LEU A 1 287  ? 218.336 352.237 257.349 1.00 39.60  ? 287  LEU A CD1   1 
ATOM   2205  C CD2   . LEU A 1 287  ? 217.216 353.786 258.965 1.00 39.60  ? 287  LEU A CD2   1 
ATOM   2206  N N     . GLN A 1 288  ? 221.345 357.127 257.293 1.00 43.73  ? 288  GLN A N     1 
ATOM   2207  C CA    . GLN A 1 288  ? 222.707 357.580 257.549 1.00 43.73  ? 288  GLN A CA    1 
ATOM   2208  C C     . GLN A 1 288  ? 222.722 358.739 258.538 1.00 43.73  ? 288  GLN A C     1 
ATOM   2209  O O     . GLN A 1 288  ? 221.871 359.632 258.492 1.00 43.73  ? 288  GLN A O     1 
ATOM   2210  C CB    . GLN A 1 288  ? 223.383 357.996 256.241 1.00 43.73  ? 288  GLN A CB    1 
ATOM   2211  C CG    . GLN A 1 288  ? 224.866 358.300 256.376 1.00 43.73  ? 288  GLN A CG    1 
ATOM   2212  C CD    . GLN A 1 288  ? 225.727 357.391 255.522 1.00 43.73  ? 288  GLN A CD    1 
ATOM   2213  O OE1   . GLN A 1 288  ? 225.752 356.176 255.718 1.00 43.73  ? 288  GLN A OE1   1 
ATOM   2214  N NE2   . GLN A 1 288  ? 226.440 357.977 254.566 1.00 43.73  ? 288  GLN A NE2   1 
ATOM   2215  N N     . GLY A 1 289  ? 223.701 358.717 259.440 1.00 54.05  ? 289  GLY A N     1 
ATOM   2216  C CA    . GLY A 1 289  ? 223.861 359.764 260.429 1.00 54.05  ? 289  GLY A CA    1 
ATOM   2217  C C     . GLY A 1 289  ? 225.311 360.149 260.638 1.00 54.05  ? 289  GLY A C     1 
ATOM   2218  O O     . GLY A 1 289  ? 226.182 359.749 259.860 1.00 54.05  ? 289  GLY A O     1 
ATOM   2219  N N     . ARG A 1 290  ? 225.586 360.926 261.687 1.00 53.70  ? 290  ARG A N     1 
ATOM   2220  C CA    . ARG A 1 290  ? 226.944 361.382 261.956 1.00 53.70  ? 290  ARG A CA    1 
ATOM   2221  C C     . ARG A 1 290  ? 227.807 360.333 262.646 1.00 53.70  ? 290  ARG A C     1 
ATOM   2222  O O     . ARG A 1 290  ? 229.035 360.467 262.637 1.00 53.70  ? 290  ARG A O     1 
ATOM   2223  C CB    . ARG A 1 290  ? 226.911 362.655 262.807 1.00 53.70  ? 290  ARG A CB    1 
ATOM   2224  C CG    . ARG A 1 290  ? 226.700 363.929 262.006 1.00 53.70  ? 290  ARG A CG    1 
ATOM   2225  C CD    . ARG A 1 290  ? 227.231 365.144 262.748 1.00 53.70  ? 290  ARG A CD    1 
ATOM   2226  N NE    . ARG A 1 290  ? 226.494 365.399 263.980 1.00 53.70  ? 290  ARG A NE    1 
ATOM   2227  C CZ    . ARG A 1 290  ? 226.940 366.152 264.977 1.00 53.70  ? 290  ARG A CZ    1 
ATOM   2228  N NH1   . ARG A 1 290  ? 228.123 366.743 264.921 1.00 53.70  ? 290  ARG A NH1   1 
ATOM   2229  N NH2   . ARG A 1 290  ? 226.181 366.316 266.056 1.00 53.70  ? 290  ARG A NH2   1 
ATOM   2230  N N     . TYR A 1 291  ? 227.206 359.299 263.233 1.00 48.14  ? 291  TYR A N     1 
ATOM   2231  C CA    . TYR A 1 291  ? 227.950 358.245 263.917 1.00 48.14  ? 291  TYR A CA    1 
ATOM   2232  C C     . TYR A 1 291  ? 227.417 356.877 263.520 1.00 48.14  ? 291  TYR A C     1 
ATOM   2233  O O     . TYR A 1 291  ? 227.239 355.991 264.362 1.00 48.14  ? 291  TYR A O     1 
ATOM   2234  C CB    . TYR A 1 291  ? 227.895 358.419 265.435 1.00 48.14  ? 291  TYR A CB    1 
ATOM   2235  C CG    . TYR A 1 291  ? 228.338 359.779 265.925 1.00 48.14  ? 291  TYR A CG    1 
ATOM   2236  C CD1   . TYR A 1 291  ? 229.636 360.225 265.715 1.00 48.14  ? 291  TYR A CD1   1 
ATOM   2237  C CD2   . TYR A 1 291  ? 227.460 360.615 266.601 1.00 48.14  ? 291  TYR A CD2   1 
ATOM   2238  C CE1   . TYR A 1 291  ? 230.046 361.467 266.163 1.00 48.14  ? 291  TYR A CE1   1 
ATOM   2239  C CE2   . TYR A 1 291  ? 227.860 361.858 267.053 1.00 48.14  ? 291  TYR A CE2   1 
ATOM   2240  C CZ    . TYR A 1 291  ? 229.154 362.279 266.831 1.00 48.14  ? 291  TYR A CZ    1 
ATOM   2241  O OH    . TYR A 1 291  ? 229.557 363.516 267.278 1.00 48.14  ? 291  TYR A OH    1 
ATOM   2242  N N     . GLY A 1 292  ? 227.156 356.686 262.234 1.00 44.88  ? 292  GLY A N     1 
ATOM   2243  C CA    . GLY A 1 292  ? 226.629 355.436 261.725 1.00 44.88  ? 292  GLY A CA    1 
ATOM   2244  C C     . GLY A 1 292  ? 225.199 355.589 261.235 1.00 44.88  ? 292  GLY A C     1 
ATOM   2245  O O     . GLY A 1 292  ? 224.675 356.692 261.068 1.00 44.88  ? 292  GLY A O     1 
ATOM   2246  N N     . CYS A 1 293  ? 224.573 354.440 261.002 1.00 43.17  ? 293  CYS A N     1 
ATOM   2247  C CA    . CYS A 1 293  ? 223.201 354.380 260.521 1.00 43.17  ? 293  CYS A CA    1 
ATOM   2248  C C     . CYS A 1 293  ? 222.288 353.811 261.600 1.00 43.17  ? 293  CYS A C     1 
ATOM   2249  O O     . CYS A 1 293  ? 222.705 352.970 262.401 1.00 43.17  ? 293  CYS A O     1 
ATOM   2250  C CB    . CYS A 1 293  ? 223.104 353.528 259.254 1.00 43.17  ? 293  CYS A CB    1 
ATOM   2251  S SG    . CYS A 1 293  ? 224.503 353.711 258.123 1.00 43.17  ? 293  CYS A SG    1 
ATOM   2252  N N     . CYS A 1 294  ? 221.046 354.287 261.623 1.00 44.58  ? 294  CYS A N     1 
ATOM   2253  C CA    . CYS A 1 294  ? 220.061 353.754 262.552 1.00 44.58  ? 294  CYS A CA    1 
ATOM   2254  C C     . CYS A 1 294  ? 219.580 352.384 262.089 1.00 44.58  ? 294  CYS A C     1 
ATOM   2255  O O     . CYS A 1 294  ? 219.598 352.065 260.897 1.00 44.58  ? 294  CYS A O     1 
ATOM   2256  C CB    . CYS A 1 294  ? 218.876 354.711 262.684 1.00 44.58  ? 294  CYS A CB    1 
ATOM   2257  S SG    . CYS A 1 294  ? 219.308 356.460 262.534 1.00 44.58  ? 294  CYS A SG    1 
ATOM   2258  N N     . ARG A 1 295  ? 219.151 351.564 263.052 1.00 40.09  ? 295  ARG A N     1 
ATOM   2259  C CA    . ARG A 1 295  ? 218.661 350.230 262.721 1.00 40.09  ? 295  ARG A CA    1 
ATOM   2260  C C     . ARG A 1 295  ? 217.419 350.306 261.842 1.00 40.09  ? 295  ARG A C     1 
ATOM   2261  O O     . ARG A 1 295  ? 217.366 349.699 260.766 1.00 40.09  ? 295  ARG A O     1 
ATOM   2262  C CB    . ARG A 1 295  ? 218.367 349.447 264.002 1.00 40.09  ? 295  ARG A CB    1 
ATOM   2263  C CG    . ARG A 1 295  ? 219.595 349.125 264.836 1.00 40.09  ? 295  ARG A CG    1 
ATOM   2264  C CD    . ARG A 1 295  ? 219.343 347.933 265.745 1.00 40.09  ? 295  ARG A CD    1 
ATOM   2265  N NE    . ARG A 1 295  ? 218.162 348.124 266.579 1.00 40.09  ? 295  ARG A NE    1 
ATOM   2266  C CZ    . ARG A 1 295  ? 217.768 347.283 267.525 1.00 40.09  ? 295  ARG A CZ    1 
ATOM   2267  N NH1   . ARG A 1 295  ? 218.440 346.174 267.787 1.00 40.09  ? 295  ARG A NH1   1 
ATOM   2268  N NH2   . ARG A 1 295  ? 216.671 347.560 268.225 1.00 40.09  ? 295  ARG A NH2   1 
ATOM   2269  N N     . PHE A 1 296  ? 216.414 351.061 262.280 1.00 51.69  ? 296  PHE A N     1 
ATOM   2270  C CA    . PHE A 1 296  ? 215.195 351.286 261.514 1.00 51.69  ? 296  PHE A CA    1 
ATOM   2271  C C     . PHE A 1 296  ? 214.437 352.433 262.166 1.00 51.69  ? 296  PHE A C     1 
ATOM   2272  O O     . PHE A 1 296  ? 214.717 352.815 263.306 1.00 51.69  ? 296  PHE A O     1 
ATOM   2273  C CB    . PHE A 1 296  ? 214.311 350.033 261.434 1.00 51.69  ? 296  PHE A CB    1 
ATOM   2274  C CG    . PHE A 1 296  ? 214.015 349.406 262.768 1.00 51.69  ? 296  PHE A CG    1 
ATOM   2275  C CD1   . PHE A 1 296  ? 214.885 348.484 263.325 1.00 51.69  ? 296  PHE A CD1   1 
ATOM   2276  C CD2   . PHE A 1 296  ? 212.856 349.727 263.456 1.00 51.69  ? 296  PHE A CD2   1 
ATOM   2277  C CE1   . PHE A 1 296  ? 214.611 347.902 264.549 1.00 51.69  ? 296  PHE A CE1   1 
ATOM   2278  C CE2   . PHE A 1 296  ? 212.576 349.148 264.679 1.00 51.69  ? 296  PHE A CE2   1 
ATOM   2279  C CZ    . PHE A 1 296  ? 213.455 348.235 265.227 1.00 51.69  ? 296  PHE A CZ    1 
ATOM   2280  N N     . LEU A 1 297  ? 213.477 352.979 261.425 1.00 58.95  ? 297  LEU A N     1 
ATOM   2281  C CA    . LEU A 1 297  ? 212.689 354.096 261.924 1.00 58.95  ? 297  LEU A CA    1 
ATOM   2282  C C     . LEU A 1 297  ? 211.796 353.658 263.080 1.00 58.95  ? 297  LEU A C     1 
ATOM   2283  O O     . LEU A 1 297  ? 211.283 352.535 263.110 1.00 58.95  ? 297  LEU A O     1 
ATOM   2284  C CB    . LEU A 1 297  ? 211.837 354.694 260.803 1.00 58.95  ? 297  LEU A CB    1 
ATOM   2285  C CG    . LEU A 1 297  ? 212.425 355.858 259.999 1.00 58.95  ? 297  LEU A CG    1 
ATOM   2286  C CD1   . LEU A 1 297  ? 212.515 357.113 260.856 1.00 58.95  ? 297  LEU A CD1   1 
ATOM   2287  C CD2   . LEU A 1 297  ? 213.784 355.508 259.409 1.00 58.95  ? 297  LEU A CD2   1 
ATOM   2288  N N     . ARG A 1 298  ? 211.618 354.566 264.041 1.00 72.88  ? 298  ARG A N     1 
ATOM   2289  C CA    . ARG A 1 298  ? 210.738 354.364 265.192 1.00 72.88  ? 298  ARG A CA    1 
ATOM   2290  C C     . ARG A 1 298  ? 211.155 353.136 266.007 1.00 72.88  ? 298  ARG A C     1 
ATOM   2291  O O     . ARG A 1 298  ? 210.421 352.153 266.129 1.00 72.88  ? 298  ARG A O     1 
ATOM   2292  C CB    . ARG A 1 298  ? 209.274 354.260 264.748 1.00 72.88  ? 298  ARG A CB    1 
ATOM   2293  C CG    . ARG A 1 298  ? 208.712 355.540 264.152 1.00 72.88  ? 298  ARG A CG    1 
ATOM   2294  C CD    . ARG A 1 298  ? 207.263 355.748 264.562 1.00 72.88  ? 298  ARG A CD    1 
ATOM   2295  N NE    . ARG A 1 298  ? 206.702 356.968 263.992 1.00 72.88  ? 298  ARG A NE    1 
ATOM   2296  C CZ    . ARG A 1 298  ? 205.470 357.402 264.218 1.00 72.88  ? 298  ARG A CZ    1 
ATOM   2297  N NH1   . ARG A 1 298  ? 204.635 356.737 265.000 1.00 72.88  ? 298  ARG A NH1   1 
ATOM   2298  N NH2   . ARG A 1 298  ? 205.064 358.531 263.644 1.00 72.88  ? 298  ARG A NH2   1 
ATOM   2299  N N     . ASP A 1 299  ? 212.361 353.211 266.568 1.00 66.74  ? 299  ASP A N     1 
ATOM   2300  C CA    . ASP A 1 299  ? 212.871 352.185 267.468 1.00 66.74  ? 299  ASP A CA    1 
ATOM   2301  C C     . ASP A 1 299  ? 213.238 352.831 268.796 1.00 66.74  ? 299  ASP A C     1 
ATOM   2302  O O     . ASP A 1 299  ? 213.828 353.916 268.822 1.00 66.74  ? 299  ASP A O     1 
ATOM   2303  C CB    . ASP A 1 299  ? 214.078 351.452 266.861 1.00 66.74  ? 299  ASP A CB    1 
ATOM   2304  C CG    . ASP A 1 299  ? 215.370 352.235 266.988 1.00 66.74  ? 299  ASP A CG    1 
ATOM   2305  O OD1   . ASP A 1 299  ? 215.670 353.038 266.081 1.00 66.74  ? 299  ASP A OD1   1 
ATOM   2306  O OD2   . ASP A 1 299  ? 216.088 352.043 267.992 1.00 66.74  ? 299  ASP A OD2   1 
ATOM   2307  N N     . GLY A 1 300  ? 212.865 352.176 269.892 1.00 69.13  ? 300  GLY A N     1 
ATOM   2308  C CA    . GLY A 1 300  ? 213.103 352.680 271.228 1.00 69.13  ? 300  GLY A CA    1 
ATOM   2309  C C     . GLY A 1 300  ? 214.232 352.024 271.991 1.00 69.13  ? 300  GLY A C     1 
ATOM   2310  O O     . GLY A 1 300  ? 214.327 352.220 273.209 1.00 69.13  ? 300  GLY A O     1 
ATOM   2311  N N     . TYR A 1 301  ? 215.086 351.250 271.328 1.00 58.88  ? 301  TYR A N     1 
ATOM   2312  C CA    . TYR A 1 301  ? 216.170 350.571 272.023 1.00 58.88  ? 301  TYR A CA    1 
ATOM   2313  C C     . TYR A 1 301  ? 217.217 351.576 272.490 1.00 58.88  ? 301  TYR A C     1 
ATOM   2314  O O     . TYR A 1 301  ? 217.650 352.441 271.722 1.00 58.88  ? 301  TYR A O     1 
ATOM   2315  C CB    . TYR A 1 301  ? 216.805 349.524 271.107 1.00 58.88  ? 301  TYR A CB    1 
ATOM   2316  C CG    . TYR A 1 301  ? 217.826 348.644 271.789 1.00 58.88  ? 301  TYR A CG    1 
ATOM   2317  C CD1   . TYR A 1 301  ? 217.431 347.646 272.670 1.00 58.88  ? 301  TYR A CD1   1 
ATOM   2318  C CD2   . TYR A 1 301  ? 219.183 348.805 271.548 1.00 58.88  ? 301  TYR A CD2   1 
ATOM   2319  C CE1   . TYR A 1 301  ? 218.359 346.836 273.295 1.00 58.88  ? 301  TYR A CE1   1 
ATOM   2320  C CE2   . TYR A 1 301  ? 220.119 348.000 272.168 1.00 58.88  ? 301  TYR A CE2   1 
ATOM   2321  C CZ    . TYR A 1 301  ? 219.702 347.017 273.040 1.00 58.88  ? 301  TYR A CZ    1 
ATOM   2322  O OH    . TYR A 1 301  ? 220.630 346.213 273.660 1.00 58.88  ? 301  TYR A OH    1 
ATOM   2323  N N     . LYS A 1 302  ? 217.620 351.452 273.754 1.00 66.17  ? 302  LYS A N     1 
ATOM   2324  C CA    . LYS A 1 302  ? 218.615 352.326 274.376 1.00 66.17  ? 302  LYS A CA    1 
ATOM   2325  C C     . LYS A 1 302  ? 218.198 353.794 274.270 1.00 66.17  ? 302  LYS A C     1 
ATOM   2326  O O     . LYS A 1 302  ? 218.850 354.619 273.628 1.00 66.17  ? 302  LYS A O     1 
ATOM   2327  C CB    . LYS A 1 302  ? 220.002 352.096 273.769 1.00 66.17  ? 302  LYS A CB    1 
ATOM   2328  C CG    . LYS A 1 302  ? 220.687 350.835 274.271 1.00 66.17  ? 302  LYS A CG    1 
ATOM   2329  C CD    . LYS A 1 302  ? 221.254 351.030 275.669 1.00 66.17  ? 302  LYS A CD    1 
ATOM   2330  C CE    . LYS A 1 302  ? 221.154 349.752 276.488 1.00 66.17  ? 302  LYS A CE    1 
ATOM   2331  N NZ    . LYS A 1 302  ? 221.696 349.927 277.864 1.00 66.17  ? 302  LYS A NZ    1 
ATOM   2332  N N     . THR A 1 303  ? 217.083 354.102 274.918 1.00 75.29  ? 303  THR A N     1 
ATOM   2333  C CA    . THR A 1 303  ? 216.484 355.425 274.932 1.00 75.29  ? 303  THR A CA    1 
ATOM   2334  C C     . THR A 1 303  ? 216.352 355.930 276.365 1.00 75.29  ? 303  THR A C     1 
ATOM   2335  O O     . THR A 1 303  ? 216.293 355.134 277.309 1.00 75.29  ? 303  THR A O     1 
ATOM   2336  C CB    . THR A 1 303  ? 215.107 355.400 274.253 1.00 75.29  ? 303  THR A CB    1 
ATOM   2337  O OG1   . THR A 1 303  ? 214.419 354.195 274.608 1.00 75.29  ? 303  THR A OG1   1 
ATOM   2338  C CG2   . THR A 1 303  ? 215.260 355.462 272.743 1.00 75.29  ? 303  THR A CG2   1 
ATOM   2339  N N     . PRO A 1 304  ? 216.303 357.258 276.567 1.00 74.18  ? 304  PRO A N     1 
ATOM   2340  C CA    . PRO A 1 304  ? 216.253 357.789 277.936 1.00 74.18  ? 304  PRO A CA    1 
ATOM   2341  C C     . PRO A 1 304  ? 214.854 357.759 278.531 1.00 74.18  ? 304  PRO A C     1 
ATOM   2342  O O     . PRO A 1 304  ? 214.585 358.456 279.513 1.00 74.18  ? 304  PRO A O     1 
ATOM   2343  C CB    . PRO A 1 304  ? 216.745 359.231 277.770 1.00 74.18  ? 304  PRO A CB    1 
ATOM   2344  C CG    . PRO A 1 304  ? 216.348 359.594 276.385 1.00 74.18  ? 304  PRO A CG    1 
ATOM   2345  C CD    . PRO A 1 304  ? 216.404 358.333 275.562 1.00 74.18  ? 304  PRO A CD    1 
ATOM   2346  N N     . LYS A 1 305  ? 213.959 356.971 277.947 1.00 81.60  ? 305  LYS A N     1 
ATOM   2347  C CA    . LYS A 1 305  ? 212.548 356.996 278.321 1.00 81.60  ? 305  LYS A CA    1 
ATOM   2348  C C     . LYS A 1 305  ? 211.990 355.582 278.188 1.00 81.60  ? 305  LYS A C     1 
ATOM   2349  O O     . LYS A 1 305  ? 212.734 354.600 278.281 1.00 81.60  ? 305  LYS A O     1 
ATOM   2350  C CB    . LYS A 1 305  ? 211.781 358.022 277.467 1.00 81.60  ? 305  LYS A CB    1 
ATOM   2351  C CG    . LYS A 1 305  ? 211.885 357.799 275.970 1.00 81.60  ? 305  LYS A CG    1 
ATOM   2352  C CD    . LYS A 1 305  ? 211.203 358.910 275.186 1.00 81.60  ? 305  LYS A CD    1 
ATOM   2353  C CE    . LYS A 1 305  ? 212.121 360.117 275.044 1.00 81.60  ? 305  LYS A CE    1 
ATOM   2354  N NZ    . LYS A 1 305  ? 211.386 361.347 274.643 1.00 81.60  ? 305  LYS A NZ    1 
ATOM   2355  N N     . GLU A 1 306  ? 210.662 355.487 278.055 1.00 88.84  ? 306  GLU A N     1 
ATOM   2356  C CA    . GLU A 1 306  ? 209.913 354.243 277.803 1.00 88.84  ? 306  GLU A CA    1 
ATOM   2357  C C     . GLU A 1 306  ? 210.185 353.160 278.843 1.00 88.84  ? 306  GLU A C     1 
ATOM   2358  O O     . GLU A 1 306  ? 209.827 351.997 278.641 1.00 88.84  ? 306  GLU A O     1 
ATOM   2359  C CB    . GLU A 1 306  ? 210.112 353.736 276.358 1.00 88.84  ? 306  GLU A CB    1 
ATOM   2360  C CG    . GLU A 1 306  ? 211.518 353.369 275.800 1.00 88.84  ? 306  GLU A CG    1 
ATOM   2361  C CD    . GLU A 1 306  ? 212.330 352.325 276.543 1.00 88.84  ? 306  GLU A CD    1 
ATOM   2362  O OE1   . GLU A 1 306  ? 213.567 352.394 276.452 1.00 88.84  ? 306  GLU A OE1   1 
ATOM   2363  O OE2   . GLU A 1 306  ? 211.762 351.361 277.098 1.00 88.84  ? 306  GLU A OE2   1 
ATOM   2364  N N     . ASP A 1 307  ? 210.711 353.557 280.010 1.00 89.70  ? 307  ASP A N     1 
ATOM   2365  C CA    . ASP A 1 307  ? 210.935 352.650 281.131 1.00 89.70  ? 307  ASP A CA    1 
ATOM   2366  C C     . ASP A 1 307  ? 211.800 351.469 280.709 1.00 89.70  ? 307  ASP A C     1 
ATOM   2367  O O     . ASP A 1 307  ? 211.279 350.370 280.486 1.00 89.70  ? 307  ASP A O     1 
ATOM   2368  C CB    . ASP A 1 307  ? 209.597 352.170 281.699 1.00 89.70  ? 307  ASP A CB    1 
ATOM   2369  C CG    . ASP A 1 307  ? 209.695 351.753 283.150 1.00 89.70  ? 307  ASP A CG    1 
ATOM   2370  O OD1   . ASP A 1 307  ? 210.246 352.522 283.969 1.00 89.70  ? 307  ASP A OD1   1 
ATOM   2371  O OD2   . ASP A 1 307  ? 209.216 350.646 283.472 1.00 89.70  ? 307  ASP A OD2   1 
ATOM   2372  N N     . PRO A 1 308  ? 213.126 351.669 280.573 1.00 90.83  ? 308  PRO A N     1 
ATOM   2373  C CA    . PRO A 1 308  ? 214.007 350.618 280.035 1.00 90.83  ? 308  PRO A CA    1 
ATOM   2374  C C     . PRO A 1 308  ? 213.812 349.239 280.652 1.00 90.83  ? 308  PRO A C     1 
ATOM   2375  O O     . PRO A 1 308  ? 214.035 348.222 279.988 1.00 90.83  ? 308  PRO A O     1 
ATOM   2376  C CB    . PRO A 1 308  ? 215.411 351.154 280.342 1.00 90.83  ? 308  PRO A CB    1 
ATOM   2377  C CG    . PRO A 1 308  ? 215.247 352.632 280.392 1.00 90.83  ? 308  PRO A CG    1 
ATOM   2378  C CD    . PRO A 1 308  ? 213.863 352.902 280.903 1.00 90.83  ? 308  PRO A CD    1 
ATOM   2379  N N     . ASN A 1 309  ? 213.403 349.190 281.918 1.00 93.27  ? 309  ASN A N     1 
ATOM   2380  C CA    . ASN A 1 309  ? 213.106 347.922 282.584 1.00 93.27  ? 309  ASN A CA    1 
ATOM   2381  C C     . ASN A 1 309  ? 211.653 347.493 282.338 1.00 93.27  ? 309  ASN A C     1 
ATOM   2382  O O     . ASN A 1 309  ? 210.895 347.132 283.239 1.00 93.27  ? 309  ASN A O     1 
ATOM   2383  C CB    . ASN A 1 309  ? 213.461 348.021 284.069 1.00 93.27  ? 309  ASN A CB    1 
ATOM   2384  C CG    . ASN A 1 309  ? 212.434 348.793 284.890 1.00 93.27  ? 309  ASN A CG    1 
ATOM   2385  O OD1   . ASN A 1 309  ? 211.605 349.526 284.353 1.00 93.27  ? 309  ASN A OD1   1 
ATOM   2386  N ND2   . ASN A 1 309  ? 212.492 348.626 286.207 1.00 93.27  ? 309  ASN A ND2   1 
ATOM   2387  N N     . ARG A 1 310  ? 211.289 347.484 281.056 1.00 95.48  ? 310  ARG A N     1 
ATOM   2388  C CA    . ARG A 1 310  ? 209.956 347.082 280.632 1.00 95.48  ? 310  ARG A CA    1 
ATOM   2389  C C     . ARG A 1 310  ? 210.044 346.468 279.243 1.00 95.48  ? 310  ARG A C     1 
ATOM   2390  O O     . ARG A 1 310  ? 211.000 346.700 278.499 1.00 95.48  ? 310  ARG A O     1 
ATOM   2391  C CB    . ARG A 1 310  ? 208.981 348.265 280.632 1.00 95.48  ? 310  ARG A CB    1 
ATOM   2392  C CG    . ARG A 1 310  ? 207.533 347.893 280.894 1.00 95.48  ? 310  ARG A CG    1 
ATOM   2393  C CD    . ARG A 1 310  ? 206.592 348.756 280.070 1.00 95.48  ? 310  ARG A CD    1 
ATOM   2394  N NE    . ARG A 1 310  ? 206.651 350.159 280.463 1.00 95.48  ? 310  ARG A NE    1 
ATOM   2395  C CZ    . ARG A 1 310  ? 206.027 350.671 281.515 1.00 95.48  ? 310  ARG A CZ    1 
ATOM   2396  N NH1   . ARG A 1 310  ? 205.273 349.923 282.304 1.00 95.48  ? 310  ARG A NH1   1 
ATOM   2397  N NH2   . ARG A 1 310  ? 206.163 351.967 281.782 1.00 95.48  ? 310  ARG A NH2   1 
ATOM   2398  N N     . LEU A 1 311  ? 209.029 345.677 278.902 1.00 95.77  ? 311  LEU A N     1 
ATOM   2399  C CA    . LEU A 1 311  ? 208.946 345.031 277.601 1.00 95.77  ? 311  LEU A CA    1 
ATOM   2400  C C     . LEU A 1 311  ? 207.506 345.096 277.107 1.00 95.77  ? 311  LEU A C     1 
ATOM   2401  O O     . LEU A 1 311  ? 206.584 345.404 277.866 1.00 95.77  ? 311  LEU A O     1 
ATOM   2402  C CB    . LEU A 1 311  ? 209.431 343.572 277.659 1.00 95.77  ? 311  LEU A CB    1 
ATOM   2403  C CG    . LEU A 1 311  ? 210.832 343.298 278.216 1.00 95.77  ? 311  LEU A CG    1 
ATOM   2404  C CD1   . LEU A 1 311  ? 210.766 342.910 279.689 1.00 95.77  ? 311  LEU A CD1   1 
ATOM   2405  C CD2   . LEU A 1 311  ? 211.543 342.220 277.409 1.00 95.77  ? 311  LEU A CD2   1 
ATOM   2406  N N     . TYR A 1 312  ? 207.330 344.800 275.817 1.00 93.58  ? 312  TYR A N     1 
ATOM   2407  C CA    . TYR A 1 312  ? 206.030 344.826 275.141 1.00 93.58  ? 312  TYR A CA    1 
ATOM   2408  C C     . TYR A 1 312  ? 205.380 346.209 275.276 1.00 93.58  ? 312  TYR A C     1 
ATOM   2409  O O     . TYR A 1 312  ? 204.308 346.381 275.861 1.00 93.58  ? 312  TYR A O     1 
ATOM   2410  C CB    . TYR A 1 312  ? 205.098 343.723 275.666 1.00 93.58  ? 312  TYR A CB    1 
ATOM   2411  C CG    . TYR A 1 312  ? 205.715 342.336 275.764 1.00 93.58  ? 312  TYR A CG    1 
ATOM   2412  C CD1   . TYR A 1 312  ? 206.482 341.963 276.863 1.00 93.58  ? 312  TYR A CD1   1 
ATOM   2413  C CD2   . TYR A 1 312  ? 205.523 341.399 274.756 1.00 93.58  ? 312  TYR A CD2   1 
ATOM   2414  C CE1   . TYR A 1 312  ? 207.041 340.699 276.952 1.00 93.58  ? 312  TYR A CE1   1 
ATOM   2415  C CE2   . TYR A 1 312  ? 206.079 340.135 274.837 1.00 93.58  ? 312  TYR A CE2   1 
ATOM   2416  C CZ    . TYR A 1 312  ? 206.837 339.791 275.936 1.00 93.58  ? 312  TYR A CZ    1 
ATOM   2417  O OH    . TYR A 1 312  ? 207.393 338.535 276.024 1.00 93.58  ? 312  TYR A OH    1 
ATOM   2418  N N     . TYR A 1 313  ? 206.077 347.195 274.707 1.00 93.34  ? 313  TYR A N     1 
ATOM   2419  C CA    . TYR A 1 313  ? 205.689 348.594 274.847 1.00 93.34  ? 313  TYR A CA    1 
ATOM   2420  C C     . TYR A 1 313  ? 204.317 348.804 274.208 1.00 93.34  ? 313  TYR A C     1 
ATOM   2421  O O     . TYR A 1 313  ? 204.061 348.336 273.095 1.00 93.34  ? 313  TYR A O     1 
ATOM   2422  C CB    . TYR A 1 313  ? 206.747 349.480 274.173 1.00 93.34  ? 313  TYR A CB    1 
ATOM   2423  C CG    . TYR A 1 313  ? 206.438 350.964 274.011 1.00 93.34  ? 313  TYR A CG    1 
ATOM   2424  C CD1   . TYR A 1 313  ? 205.470 351.595 274.781 1.00 93.34  ? 313  TYR A CD1   1 
ATOM   2425  C CD2   . TYR A 1 313  ? 207.251 351.768 273.226 1.00 93.34  ? 313  TYR A CD2   1 
ATOM   2426  C CE1   . TYR A 1 313  ? 205.218 352.946 274.660 1.00 93.34  ? 313  TYR A CE1   1 
ATOM   2427  C CE2   . TYR A 1 313  ? 207.006 353.123 273.098 1.00 93.34  ? 313  TYR A CE2   1 
ATOM   2428  C CZ    . TYR A 1 313  ? 205.996 353.706 273.823 1.00 93.34  ? 313  TYR A CZ    1 
ATOM   2429  O OH    . TYR A 1 313  ? 205.760 355.057 273.715 1.00 93.34  ? 313  TYR A OH    1 
ATOM   2430  N N     . GLU A 1 314  ? 203.443 349.521 274.915 1.00 94.87  ? 314  GLU A N     1 
ATOM   2431  C CA    . GLU A 1 314  ? 202.114 349.847 274.426 1.00 94.87  ? 314  GLU A CA    1 
ATOM   2432  C C     . GLU A 1 314  ? 202.195 350.722 273.174 1.00 94.87  ? 314  GLU A C     1 
ATOM   2433  O O     . GLU A 1 314  ? 203.195 351.399 272.940 1.00 94.87  ? 314  GLU A O     1 
ATOM   2434  C CB    . GLU A 1 314  ? 201.321 350.561 275.522 1.00 94.87  ? 314  GLU A CB    1 
ATOM   2435  C CG    . GLU A 1 314  ? 201.909 351.906 275.933 1.00 94.87  ? 314  GLU A CG    1 
ATOM   2436  C CD    . GLU A 1 314  ? 201.621 352.261 277.384 1.00 94.87  ? 314  GLU A CD    1 
ATOM   2437  O OE1   . GLU A 1 314  ? 200.769 351.595 278.009 1.00 94.87  ? 314  GLU A OE1   1 
ATOM   2438  O OE2   . GLU A 1 314  ? 202.256 353.199 277.910 1.00 94.87  ? 314  GLU A OE2   1 
ATOM   2439  N N     . PRO A 1 315  ? 201.151 350.707 272.334 1.00 95.82  ? 315  PRO A N     1 
ATOM   2440  C CA    . PRO A 1 315  ? 201.194 351.508 271.099 1.00 95.82  ? 315  PRO A CA    1 
ATOM   2441  C C     . PRO A 1 315  ? 201.092 353.002 271.367 1.00 95.82  ? 315  PRO A C     1 
ATOM   2442  O O     . PRO A 1 315  ? 200.033 353.603 271.161 1.00 95.82  ? 315  PRO A O     1 
ATOM   2443  C CB    . PRO A 1 315  ? 199.983 351.003 270.299 1.00 95.82  ? 315  PRO A CB    1 
ATOM   2444  C CG    . PRO A 1 315  ? 199.549 349.737 270.965 1.00 95.82  ? 315  PRO A CG    1 
ATOM   2445  C CD    . PRO A 1 315  ? 199.950 349.858 272.401 1.00 95.82  ? 315  PRO A CD    1 
ATOM   2446  N N     . ALA A 1 316  ? 202.190 353.611 271.830 1.00 91.94  ? 316  ALA A N     1 
ATOM   2447  C CA    . ALA A 1 316  ? 202.228 355.043 272.106 1.00 91.94  ? 316  ALA A CA    1 
ATOM   2448  C C     . ALA A 1 316  ? 203.548 355.667 271.663 1.00 91.94  ? 316  ALA A C     1 
ATOM   2449  O O     . ALA A 1 316  ? 204.099 356.525 272.362 1.00 91.94  ? 316  ALA A O     1 
ATOM   2450  C CB    . ALA A 1 316  ? 201.989 355.323 273.591 1.00 91.94  ? 316  ALA A CB    1 
ATOM   2451  N N     . GLU A 1 317  ? 204.071 355.248 270.513 1.00 90.65  ? 317  GLU A N     1 
ATOM   2452  C CA    . GLU A 1 317  ? 205.336 355.742 269.978 1.00 90.65  ? 317  GLU A CA    1 
ATOM   2453  C C     . GLU A 1 317  ? 205.118 356.774 268.873 1.00 90.65  ? 317  GLU A C     1 
ATOM   2454  O O     . GLU A 1 317  ? 205.865 356.828 267.894 1.00 90.65  ? 317  GLU A O     1 
ATOM   2455  C CB    . GLU A 1 317  ? 206.198 354.584 269.479 1.00 90.65  ? 317  GLU A CB    1 
ATOM   2456  C CG    . GLU A 1 317  ? 205.625 353.814 268.294 1.00 90.65  ? 317  GLU A CG    1 
ATOM   2457  C CD    . GLU A 1 317  ? 206.168 352.401 268.207 1.00 90.65  ? 317  GLU A CD    1 
ATOM   2458  O OE1   . GLU A 1 317  ? 206.988 352.026 269.071 1.00 90.65  ? 317  GLU A OE1   1 
ATOM   2459  O OE2   . GLU A 1 317  ? 205.789 351.672 267.265 1.00 90.65  ? 317  GLU A OE2   1 
ATOM   2460  N N     . LEU A 1 318  ? 204.092 357.615 269.030 1.00 101.34 ? 318  LEU A N     1 
ATOM   2461  C CA    . LEU A 1 318  ? 203.750 358.582 267.990 1.00 101.34 ? 318  LEU A CA    1 
ATOM   2462  C C     . LEU A 1 318  ? 204.914 359.525 267.695 1.00 101.34 ? 318  LEU A C     1 
ATOM   2463  O O     . LEU A 1 318  ? 205.246 359.771 266.529 1.00 101.34 ? 318  LEU A O     1 
ATOM   2464  C CB    . LEU A 1 318  ? 202.497 359.368 268.395 1.00 101.34 ? 318  LEU A CB    1 
ATOM   2465  C CG    . LEU A 1 318  ? 202.548 360.383 269.546 1.00 101.34 ? 318  LEU A CG    1 
ATOM   2466  C CD1   . LEU A 1 318  ? 201.355 361.321 269.494 1.00 101.34 ? 318  LEU A CD1   1 
ATOM   2467  C CD2   . LEU A 1 318  ? 202.614 359.696 270.904 1.00 101.34 ? 318  LEU A CD2   1 
ATOM   2468  N N     . LYS A 1 319  ? 205.552 360.060 268.739 1.00 103.14 ? 319  LYS A N     1 
ATOM   2469  C CA    . LYS A 1 319  ? 206.635 361.017 268.560 1.00 103.14 ? 319  LYS A CA    1 
ATOM   2470  C C     . LYS A 1 319  ? 207.785 360.836 269.540 1.00 103.14 ? 319  LYS A C     1 
ATOM   2471  O O     . LYS A 1 319  ? 208.704 361.662 269.536 1.00 103.14 ? 319  LYS A O     1 
ATOM   2472  C CB    . LYS A 1 319  ? 206.103 362.459 268.678 1.00 103.14 ? 319  LYS A CB    1 
ATOM   2473  C CG    . LYS A 1 319  ? 205.074 362.851 267.627 1.00 103.14 ? 319  LYS A CG    1 
ATOM   2474  C CD    . LYS A 1 319  ? 205.136 364.340 267.324 1.00 103.14 ? 319  LYS A CD    1 
ATOM   2475  C CE    . LYS A 1 319  ? 204.121 364.737 266.264 1.00 103.14 ? 319  LYS A CE    1 
ATOM   2476  N NZ    . LYS A 1 319  ? 204.763 365.431 265.113 1.00 103.14 ? 319  LYS A NZ    1 
ATOM   2477  N N     . LEU A 1 320  ? 207.768 359.799 270.380 1.00 91.59  ? 320  LEU A N     1 
ATOM   2478  C CA    . LEU A 1 320  ? 208.753 359.709 271.453 1.00 91.59  ? 320  LEU A CA    1 
ATOM   2479  C C     . LEU A 1 320  ? 210.142 359.368 270.925 1.00 91.59  ? 320  LEU A C     1 
ATOM   2480  O O     . LEU A 1 320  ? 211.129 360.000 271.317 1.00 91.59  ? 320  LEU A O     1 
ATOM   2481  C CB    . LEU A 1 320  ? 208.301 358.688 272.498 1.00 91.59  ? 320  LEU A CB    1 
ATOM   2482  C CG    . LEU A 1 320  ? 206.935 358.971 273.128 1.00 91.59  ? 320  LEU A CG    1 
ATOM   2483  C CD1   . LEU A 1 320  ? 206.649 357.997 274.256 1.00 91.59  ? 320  LEU A CD1   1 
ATOM   2484  C CD2   . LEU A 1 320  ? 206.858 360.408 273.625 1.00 91.59  ? 320  LEU A CD2   1 
ATOM   2485  N N     . PHE A 1 321  ? 210.247 358.378 270.038 1.00 84.12  ? 321  PHE A N     1 
ATOM   2486  C CA    . PHE A 1 321  ? 211.538 357.957 269.504 1.00 84.12  ? 321  PHE A CA    1 
ATOM   2487  C C     . PHE A 1 321  ? 211.818 358.500 268.111 1.00 84.12  ? 321  PHE A C     1 
ATOM   2488  O O     . PHE A 1 321  ? 212.824 358.119 267.505 1.00 84.12  ? 321  PHE A O     1 
ATOM   2489  C CB    . PHE A 1 321  ? 211.646 356.431 269.473 1.00 84.12  ? 321  PHE A CB    1 
ATOM   2490  C CG    . PHE A 1 321  ? 211.110 355.755 270.694 1.00 84.12  ? 321  PHE A CG    1 
ATOM   2491  C CD1   . PHE A 1 321  ? 211.410 356.230 271.959 1.00 84.12  ? 321  PHE A CD1   1 
ATOM   2492  C CD2   . PHE A 1 321  ? 210.312 354.633 270.575 1.00 84.12  ? 321  PHE A CD2   1 
ATOM   2493  C CE1   . PHE A 1 321  ? 210.918 355.600 273.080 1.00 84.12  ? 321  PHE A CE1   1 
ATOM   2494  C CE2   . PHE A 1 321  ? 209.822 354.000 271.688 1.00 84.12  ? 321  PHE A CE2   1 
ATOM   2495  C CZ    . PHE A 1 321  ? 210.120 354.485 272.941 1.00 84.12  ? 321  PHE A CZ    1 
ATOM   2496  N N     . GLU A 1 322  ? 210.965 359.372 267.587 1.00 83.10  ? 322  GLU A N     1 
ATOM   2497  C CA    . GLU A 1 322  ? 211.158 359.903 266.247 1.00 83.10  ? 322  GLU A CA    1 
ATOM   2498  C C     . GLU A 1 322  ? 212.295 360.916 266.259 1.00 83.10  ? 322  GLU A C     1 
ATOM   2499  O O     . GLU A 1 322  ? 212.348 361.790 267.131 1.00 83.10  ? 322  GLU A O     1 
ATOM   2500  C CB    . GLU A 1 322  ? 209.874 360.545 265.720 1.00 83.10  ? 322  GLU A CB    1 
ATOM   2501  C CG    . GLU A 1 322  ? 209.865 360.740 264.211 1.00 83.10  ? 322  GLU A CG    1 
ATOM   2502  C CD    . GLU A 1 322  ? 208.487 360.565 263.604 1.00 83.10  ? 322  GLU A CD    1 
ATOM   2503  O OE1   . GLU A 1 322  ? 207.866 359.506 263.831 1.00 83.10  ? 322  GLU A OE1   1 
ATOM   2504  O OE2   . GLU A 1 322  ? 208.026 361.486 262.896 1.00 83.10  ? 322  GLU A OE2   1 
ATOM   2505  N N     . ASN A 1 323  ? 213.210 360.776 265.301 1.00 82.92  ? 323  ASN A N     1 
ATOM   2506  C CA    . ASN A 1 323  ? 214.359 361.642 265.040 1.00 82.92  ? 323  ASN A CA    1 
ATOM   2507  C C     . ASN A 1 323  ? 215.459 361.517 266.092 1.00 82.92  ? 323  ASN A C     1 
ATOM   2508  O O     . ASN A 1 323  ? 216.464 362.228 265.982 1.00 82.92  ? 323  ASN A O     1 
ATOM   2509  C CB    . ASN A 1 323  ? 213.967 363.124 264.915 1.00 82.92  ? 323  ASN A CB    1 
ATOM   2510  C CG    . ASN A 1 323  ? 214.703 363.828 263.794 1.00 82.92  ? 323  ASN A CG    1 
ATOM   2511  O OD1   . ASN A 1 323  ? 215.839 363.483 263.469 1.00 82.92  ? 323  ASN A OD1   1 
ATOM   2512  N ND2   . ASN A 1 323  ? 214.056 364.820 263.193 1.00 82.92  ? 323  ASN A ND2   1 
ATOM   2513  N N     . ILE A 1 324  ? 215.322 360.649 267.095 1.00 75.55  ? 324  ILE A N     1 
ATOM   2514  C CA    . ILE A 1 324  ? 216.366 360.501 268.106 1.00 75.55  ? 324  ILE A CA    1 
ATOM   2515  C C     . ILE A 1 324  ? 216.800 359.044 268.199 1.00 75.55  ? 324  ILE A C     1 
ATOM   2516  O O     . ILE A 1 324  ? 217.266 358.591 269.250 1.00 75.55  ? 324  ILE A O     1 
ATOM   2517  C CB    . ILE A 1 324  ? 215.902 361.016 269.481 1.00 75.55  ? 324  ILE A CB    1 
ATOM   2518  C CG1   . ILE A 1 324  ? 214.591 360.351 269.897 1.00 75.55  ? 324  ILE A CG1   1 
ATOM   2519  C CG2   . ILE A 1 324  ? 215.740 362.526 269.462 1.00 75.55  ? 324  ILE A CG2   1 
ATOM   2520  C CD1   . ILE A 1 324  ? 214.189 360.673 271.318 1.00 75.55  ? 324  ILE A CD1   1 
ATOM   2521  N N     . GLU A 1 325  ? 216.653 358.302 267.105 1.00 74.40  ? 325  GLU A N     1 
ATOM   2522  C CA    . GLU A 1 325  ? 217.053 356.903 267.097 1.00 74.40  ? 325  GLU A CA    1 
ATOM   2523  C C     . GLU A 1 325  ? 218.572 356.771 267.128 1.00 74.40  ? 325  GLU A C     1 
ATOM   2524  O O     . GLU A 1 325  ? 219.305 357.609 266.595 1.00 74.40  ? 325  GLU A O     1 
ATOM   2525  C CB    . GLU A 1 325  ? 216.490 356.192 265.866 1.00 74.40  ? 325  GLU A CB    1 
ATOM   2526  C CG    . GLU A 1 325  ? 214.972 356.177 265.800 1.00 74.40  ? 325  GLU A CG    1 
ATOM   2527  C CD    . GLU A 1 325  ? 214.419 357.250 264.887 1.00 74.40  ? 325  GLU A CD    1 
ATOM   2528  O OE1   . GLU A 1 325  ? 214.769 358.433 265.080 1.00 74.40  ? 325  GLU A OE1   1 
ATOM   2529  O OE2   . GLU A 1 325  ? 213.634 356.912 263.977 1.00 74.40  ? 325  GLU A OE2   1 
ATOM   2530  N N     . CYS A 1 326  ? 219.041 355.701 267.765 1.00 63.64  ? 326  CYS A N     1 
ATOM   2531  C CA    . CYS A 1 326  ? 220.469 355.445 267.862 1.00 63.64  ? 326  CYS A CA    1 
ATOM   2532  C C     . CYS A 1 326  ? 221.021 354.952 266.526 1.00 63.64  ? 326  CYS A C     1 
ATOM   2533  O O     . CYS A 1 326  ? 220.291 354.446 265.669 1.00 63.64  ? 326  CYS A O     1 
ATOM   2534  C CB    . CYS A 1 326  ? 220.755 354.420 268.959 1.00 63.64  ? 326  CYS A CB    1 
ATOM   2535  S SG    . CYS A 1 326  ? 220.379 354.992 270.633 1.00 63.64  ? 326  CYS A SG    1 
ATOM   2536  N N     . GLU A 1 327  ? 222.332 355.103 266.358 1.00 55.36  ? 327  GLU A N     1 
ATOM   2537  C CA    . GLU A 1 327  ? 223.022 354.728 265.132 1.00 55.36  ? 327  GLU A CA    1 
ATOM   2538  C C     . GLU A 1 327  ? 224.149 353.753 265.446 1.00 55.36  ? 327  GLU A C     1 
ATOM   2539  O O     . GLU A 1 327  ? 224.811 353.866 266.483 1.00 55.36  ? 327  GLU A O     1 
ATOM   2540  C CB    . GLU A 1 327  ? 223.573 355.964 264.412 1.00 55.36  ? 327  GLU A CB    1 
ATOM   2541  C CG    . GLU A 1 327  ? 224.159 357.014 265.341 1.00 55.36  ? 327  GLU A CG    1 
ATOM   2542  C CD    . GLU A 1 327  ? 224.468 358.314 264.625 1.00 55.36  ? 327  GLU A CD    1 
ATOM   2543  O OE1   . GLU A 1 327  ? 224.779 359.311 265.308 1.00 55.36  ? 327  GLU A OE1   1 
ATOM   2544  O OE2   . GLU A 1 327  ? 224.398 358.339 263.379 1.00 55.36  ? 327  GLU A OE2   1 
ATOM   2545  N N     . TRP A 1 328  ? 224.363 352.796 264.542 1.00 64.40  ? 328  TRP A N     1 
ATOM   2546  C CA    . TRP A 1 328  ? 225.323 351.719 264.750 1.00 64.40  ? 328  TRP A CA    1 
ATOM   2547  C C     . TRP A 1 328  ? 226.420 351.784 263.697 1.00 64.40  ? 328  TRP A C     1 
ATOM   2548  O O     . TRP A 1 328  ? 226.113 351.831 262.496 1.00 64.40  ? 328  TRP A O     1 
ATOM   2549  C CB    . TRP A 1 328  ? 224.625 350.359 264.701 1.00 64.40  ? 328  TRP A CB    1 
ATOM   2550  C CG    . TRP A 1 328  ? 223.617 350.130 265.793 1.00 64.40  ? 328  TRP A CG    1 
ATOM   2551  C CD1   . TRP A 1 328  ? 222.583 350.950 266.145 1.00 64.40  ? 328  TRP A CD1   1 
ATOM   2552  C CD2   . TRP A 1 328  ? 223.543 348.996 266.666 1.00 64.40  ? 328  TRP A CD2   1 
ATOM   2553  N NE1   . TRP A 1 328  ? 221.876 350.400 267.187 1.00 64.40  ? 328  TRP A NE1   1 
ATOM   2554  C CE2   . TRP A 1 328  ? 222.444 349.200 267.525 1.00 64.40  ? 328  TRP A CE2   1 
ATOM   2555  C CE3   . TRP A 1 328  ? 224.301 347.830 266.807 1.00 64.40  ? 328  TRP A CE3   1 
ATOM   2556  C CZ2   . TRP A 1 328  ? 222.085 348.282 268.509 1.00 64.40  ? 328  TRP A CZ2   1 
ATOM   2557  C CZ3   . TRP A 1 328  ? 223.943 346.919 267.785 1.00 64.40  ? 328  TRP A CZ3   1 
ATOM   2558  C CH2   . TRP A 1 328  ? 222.845 347.151 268.623 1.00 64.40  ? 328  TRP A CH2   1 
ATOM   2559  N N     . PRO A 1 329  ? 227.697 351.790 264.088 1.00 41.97  ? 329  PRO A N     1 
ATOM   2560  C CA    . PRO A 1 329  ? 228.774 351.736 263.083 1.00 41.97  ? 329  PRO A CA    1 
ATOM   2561  C C     . PRO A 1 329  ? 228.870 350.400 262.363 1.00 41.97  ? 329  PRO A C     1 
ATOM   2562  O O     . PRO A 1 329  ? 229.637 350.285 261.396 1.00 41.97  ? 329  PRO A O     1 
ATOM   2563  C CB    . PRO A 1 329  ? 230.040 352.017 263.906 1.00 41.97  ? 329  PRO A CB    1 
ATOM   2564  C CG    . PRO A 1 329  ? 229.552 352.665 265.167 1.00 41.97  ? 329  PRO A CG    1 
ATOM   2565  C CD    . PRO A 1 329  ? 228.214 352.053 265.440 1.00 41.97  ? 329  PRO A CD    1 
ATOM   2566  N N     . LEU A 1 330  ? 228.131 349.382 262.815 1.00 45.94  ? 330  LEU A N     1 
ATOM   2567  C CA    . LEU A 1 330  ? 228.152 348.087 262.141 1.00 45.94  ? 330  LEU A CA    1 
ATOM   2568  C C     . LEU A 1 330  ? 227.686 348.214 260.697 1.00 45.94  ? 330  LEU A C     1 
ATOM   2569  O O     . LEU A 1 330  ? 228.199 347.531 259.803 1.00 45.94  ? 330  LEU A O     1 
ATOM   2570  C CB    . LEU A 1 330  ? 227.281 347.089 262.906 1.00 45.94  ? 330  LEU A CB    1 
ATOM   2571  C CG    . LEU A 1 330  ? 227.097 345.704 262.284 1.00 45.94  ? 330  LEU A CG    1 
ATOM   2572  C CD1   . LEU A 1 330  ? 228.269 344.806 262.639 1.00 45.94  ? 330  LEU A CD1   1 
ATOM   2573  C CD2   . LEU A 1 330  ? 225.784 345.083 262.734 1.00 45.94  ? 330  LEU A CD2   1 
ATOM   2574  N N     . PHE A 1 331  ? 226.720 349.098 260.445 1.00 33.81  ? 331  PHE A N     1 
ATOM   2575  C CA    . PHE A 1 331  ? 226.278 349.331 259.075 1.00 33.81  ? 331  PHE A CA    1 
ATOM   2576  C C     . PHE A 1 331  ? 227.340 350.062 258.263 1.00 33.81  ? 331  PHE A C     1 
ATOM   2577  O O     . PHE A 1 331  ? 227.455 349.842 257.051 1.00 33.81  ? 331  PHE A O     1 
ATOM   2578  C CB    . PHE A 1 331  ? 224.960 350.102 259.089 1.00 33.81  ? 331  PHE A CB    1 
ATOM   2579  C CG    . PHE A 1 331  ? 223.950 349.538 260.049 1.00 33.81  ? 331  PHE A CG    1 
ATOM   2580  C CD1   . PHE A 1 331  ? 223.668 348.181 260.058 1.00 33.81  ? 331  PHE A CD1   1 
ATOM   2581  C CD2   . PHE A 1 331  ? 223.303 350.356 260.957 1.00 33.81  ? 331  PHE A CD2   1 
ATOM   2582  C CE1   . PHE A 1 331  ? 222.748 347.655 260.945 1.00 33.81  ? 331  PHE A CE1   1 
ATOM   2583  C CE2   . PHE A 1 331  ? 222.382 349.837 261.848 1.00 33.81  ? 331  PHE A CE2   1 
ATOM   2584  C CZ    . PHE A 1 331  ? 222.104 348.484 261.842 1.00 33.81  ? 331  PHE A CZ    1 
ATOM   2585  N N     . TRP A 1 332  ? 228.138 350.917 258.907 1.00 42.48  ? 332  TRP A N     1 
ATOM   2586  C CA    . TRP A 1 332  ? 229.278 351.515 258.219 1.00 42.48  ? 332  TRP A CA    1 
ATOM   2587  C C     . TRP A 1 332  ? 230.304 350.453 257.838 1.00 42.48  ? 332  TRP A C     1 
ATOM   2588  O O     . TRP A 1 332  ? 230.893 350.509 256.752 1.00 42.48  ? 332  TRP A O     1 
ATOM   2589  C CB    . TRP A 1 332  ? 229.915 352.597 259.091 1.00 42.48  ? 332  TRP A CB    1 
ATOM   2590  C CG    . TRP A 1 332  ? 229.253 353.936 258.954 1.00 42.48  ? 332  TRP A CG    1 
ATOM   2591  C CD1   . TRP A 1 332  ? 228.061 354.201 258.346 1.00 42.48  ? 332  TRP A CD1   1 
ATOM   2592  C CD2   . TRP A 1 332  ? 229.748 355.193 259.431 1.00 42.48  ? 332  TRP A CD2   1 
ATOM   2593  N NE1   . TRP A 1 332  ? 227.782 355.544 258.417 1.00 42.48  ? 332  TRP A NE1   1 
ATOM   2594  C CE2   . TRP A 1 332  ? 228.802 356.176 259.078 1.00 42.48  ? 332  TRP A CE2   1 
ATOM   2595  C CE3   . TRP A 1 332  ? 230.899 355.583 260.123 1.00 42.48  ? 332  TRP A CE3   1 
ATOM   2596  C CZ2   . TRP A 1 332  ? 228.971 357.522 259.393 1.00 42.48  ? 332  TRP A CZ2   1 
ATOM   2597  C CZ3   . TRP A 1 332  ? 231.064 356.920 260.435 1.00 42.48  ? 332  TRP A CZ3   1 
ATOM   2598  C CH2   . TRP A 1 332  ? 230.106 357.874 260.070 1.00 42.48  ? 332  TRP A CH2   1 
ATOM   2599  N N     . THR A 1 333  ? 230.533 349.476 258.720 1.00 36.97  ? 333  THR A N     1 
ATOM   2600  C CA    . THR A 1 333  ? 231.417 348.366 258.370 1.00 36.97  ? 333  THR A CA    1 
ATOM   2601  C C     . THR A 1 333  ? 230.834 347.539 257.228 1.00 36.97  ? 333  THR A C     1 
ATOM   2602  O O     . THR A 1 333  ? 231.571 347.065 256.353 1.00 36.97  ? 333  THR A O     1 
ATOM   2603  C CB    . THR A 1 333  ? 231.677 347.485 259.592 1.00 36.97  ? 333  THR A CB    1 
ATOM   2604  O OG1   . THR A 1 333  ? 230.433 346.997 260.107 1.00 36.97  ? 333  THR A OG1   1 
ATOM   2605  C CG2   . THR A 1 333  ? 232.394 348.277 260.676 1.00 36.97  ? 333  THR A CG2   1 
ATOM   2606  N N     . TYR A 1 334  ? 229.513 347.342 257.232 1.00 31.08  ? 334  TYR A N     1 
ATOM   2607  C CA    . TYR A 1 334  ? 228.848 346.688 256.107 1.00 31.08  ? 334  TYR A CA    1 
ATOM   2608  C C     . TYR A 1 334  ? 229.105 347.435 254.804 1.00 31.08  ? 334  TYR A C     1 
ATOM   2609  O O     . TYR A 1 334  ? 229.404 346.819 253.773 1.00 31.08  ? 334  TYR A O     1 
ATOM   2610  C CB    . TYR A 1 334  ? 227.343 346.597 256.365 1.00 31.08  ? 334  TYR A CB    1 
ATOM   2611  C CG    . TYR A 1 334  ? 226.898 345.385 257.149 1.00 31.08  ? 334  TYR A CG    1 
ATOM   2612  C CD1   . TYR A 1 334  ? 227.756 344.317 257.367 1.00 31.08  ? 334  TYR A CD1   1 
ATOM   2613  C CD2   . TYR A 1 334  ? 225.605 345.299 257.650 1.00 31.08  ? 334  TYR A CD2   1 
ATOM   2614  C CE1   . TYR A 1 334  ? 227.343 343.204 258.075 1.00 31.08  ? 334  TYR A CE1   1 
ATOM   2615  C CE2   . TYR A 1 334  ? 225.185 344.193 258.361 1.00 31.08  ? 334  TYR A CE2   1 
ATOM   2616  C CZ    . TYR A 1 334  ? 226.058 343.148 258.570 1.00 31.08  ? 334  TYR A CZ    1 
ATOM   2617  O OH    . TYR A 1 334  ? 225.644 342.043 259.277 1.00 31.08  ? 334  TYR A OH    1 
ATOM   2618  N N     . PHE A 1 335  ? 228.977 348.763 254.832 1.00 40.55  ? 335  PHE A N     1 
ATOM   2619  C CA    . PHE A 1 335  ? 229.232 349.563 253.638 1.00 40.55  ? 335  PHE A CA    1 
ATOM   2620  C C     . PHE A 1 335  ? 230.685 349.444 253.197 1.00 40.55  ? 335  PHE A C     1 
ATOM   2621  O O     . PHE A 1 335  ? 230.974 349.367 251.997 1.00 40.55  ? 335  PHE A O     1 
ATOM   2622  C CB    . PHE A 1 335  ? 228.869 351.025 253.898 1.00 40.55  ? 335  PHE A CB    1 
ATOM   2623  C CG    . PHE A 1 335  ? 227.444 351.362 253.568 1.00 40.55  ? 335  PHE A CG    1 
ATOM   2624  C CD1   . PHE A 1 335  ? 226.987 351.300 252.262 1.00 40.55  ? 335  PHE A CD1   1 
ATOM   2625  C CD2   . PHE A 1 335  ? 226.561 351.745 254.564 1.00 40.55  ? 335  PHE A CD2   1 
ATOM   2626  C CE1   . PHE A 1 335  ? 225.676 351.610 251.956 1.00 40.55  ? 335  PHE A CE1   1 
ATOM   2627  C CE2   . PHE A 1 335  ? 225.249 352.058 254.265 1.00 40.55  ? 335  PHE A CE2   1 
ATOM   2628  C CZ    . PHE A 1 335  ? 224.806 351.989 252.959 1.00 40.55  ? 335  PHE A CZ    1 
ATOM   2629  N N     . ILE A 1 336  ? 231.614 349.434 254.156 1.00 30.16  ? 336  ILE A N     1 
ATOM   2630  C CA    . ILE A 1 336  ? 233.030 349.280 253.829 1.00 30.16  ? 336  ILE A CA    1 
ATOM   2631  C C     . ILE A 1 336  ? 233.273 347.945 253.136 1.00 30.16  ? 336  ILE A C     1 
ATOM   2632  O O     . ILE A 1 336  ? 233.975 347.874 252.119 1.00 30.16  ? 336  ILE A O     1 
ATOM   2633  C CB    . ILE A 1 336  ? 233.890 349.423 255.100 1.00 30.16  ? 336  ILE A CB    1 
ATOM   2634  C CG1   . ILE A 1 336  ? 234.190 350.895 255.382 1.00 30.16  ? 336  ILE A CG1   1 
ATOM   2635  C CG2   . ILE A 1 336  ? 235.187 348.635 254.970 1.00 30.16  ? 336  ILE A CG2   1 
ATOM   2636  C CD1   . ILE A 1 336  ? 235.112 351.117 256.561 1.00 30.16  ? 336  ILE A CD1   1 
ATOM   2637  N N     . LEU A 1 337  ? 232.694 346.868 253.673 1.00 32.04  ? 337  LEU A N     1 
ATOM   2638  C CA    . LEU A 1 337  ? 232.865 345.549 253.070 1.00 32.04  ? 337  LEU A CA    1 
ATOM   2639  C C     . LEU A 1 337  ? 232.264 345.504 251.670 1.00 32.04  ? 337  LEU A C     1 
ATOM   2640  O O     . LEU A 1 337  ? 232.876 344.973 250.733 1.00 32.04  ? 337  LEU A O     1 
ATOM   2641  C CB    . LEU A 1 337  ? 232.232 344.478 253.961 1.00 32.04  ? 337  LEU A CB    1 
ATOM   2642  C CG    . LEU A 1 337  ? 233.149 343.736 254.936 1.00 32.04  ? 337  LEU A CG    1 
ATOM   2643  C CD1   . LEU A 1 337  ? 234.214 342.951 254.183 1.00 32.04  ? 337  LEU A CD1   1 
ATOM   2644  C CD2   . LEU A 1 337  ? 233.783 344.694 255.933 1.00 32.04  ? 337  LEU A CD2   1 
ATOM   2645  N N     . ASP A 1 338  ? 231.063 346.065 251.508 1.00 35.86  ? 338  ASP A N     1 
ATOM   2646  C CA    . ASP A 1 338  ? 230.414 346.069 250.202 1.00 35.86  ? 338  ASP A CA    1 
ATOM   2647  C C     . ASP A 1 338  ? 231.239 346.839 249.179 1.00 35.86  ? 338  ASP A C     1 
ATOM   2648  O O     . ASP A 1 338  ? 231.387 346.400 248.033 1.00 35.86  ? 338  ASP A O     1 
ATOM   2649  C CB    . ASP A 1 338  ? 229.010 346.662 250.316 1.00 35.86  ? 338  ASP A CB    1 
ATOM   2650  C CG    . ASP A 1 338  ? 228.459 347.117 248.979 1.00 35.86  ? 338  ASP A CG    1 
ATOM   2651  O OD1   . ASP A 1 338  ? 228.451 346.307 248.028 1.00 35.86  ? 338  ASP A OD1   1 
ATOM   2652  O OD2   . ASP A 1 338  ? 228.038 348.289 248.877 1.00 35.86  ? 338  ASP A OD2   1 
ATOM   2653  N N     . GLY A 1 339  ? 231.780 347.992 249.575 1.00 33.83  ? 339  GLY A N     1 
ATOM   2654  C CA    . GLY A 1 339  ? 232.614 348.753 248.662 1.00 33.83  ? 339  GLY A CA    1 
ATOM   2655  C C     . GLY A 1 339  ? 233.899 348.033 248.301 1.00 33.83  ? 339  GLY A C     1 
ATOM   2656  O O     . GLY A 1 339  ? 234.277 347.969 247.130 1.00 33.83  ? 339  GLY A O     1 
ATOM   2657  N N     . VAL A 1 340  ? 234.582 347.467 249.301 1.00 33.88  ? 340  VAL A N     1 
ATOM   2658  C CA    . VAL A 1 340  ? 235.871 346.826 249.045 1.00 33.88  ? 340  VAL A CA    1 
ATOM   2659  C C     . VAL A 1 340  ? 235.725 345.508 248.305 1.00 33.88  ? 340  VAL A C     1 
ATOM   2660  O O     . VAL A 1 340  ? 236.696 345.039 247.697 1.00 33.88  ? 340  VAL A O     1 
ATOM   2661  C CB    . VAL A 1 340  ? 236.642 346.612 250.364 1.00 33.88  ? 340  VAL A CB    1 
ATOM   2662  C CG1   . VAL A 1 340  ? 236.009 345.503 251.192 1.00 33.88  ? 340  VAL A CG1   1 
ATOM   2663  C CG2   . VAL A 1 340  ? 238.120 346.335 250.101 1.00 33.88  ? 340  VAL A CG2   1 
ATOM   2664  N N     . PHE A 1 341  ? 234.536 344.904 248.313 1.00 36.77  ? 341  PHE A N     1 
ATOM   2665  C CA    . PHE A 1 341  ? 234.382 343.598 247.673 1.00 36.77  ? 341  PHE A CA    1 
ATOM   2666  C C     . PHE A 1 341  ? 234.252 343.719 246.156 1.00 36.77  ? 341  PHE A C     1 
ATOM   2667  O O     . PHE A 1 341  ? 235.118 343.254 245.410 1.00 36.77  ? 341  PHE A O     1 
ATOM   2668  C CB    . PHE A 1 341  ? 233.174 342.868 248.266 1.00 36.77  ? 341  PHE A CB    1 
ATOM   2669  C CG    . PHE A 1 341  ? 233.452 341.442 248.638 1.00 36.77  ? 341  PHE A CG    1 
ATOM   2670  C CD1   . PHE A 1 341  ? 234.074 341.134 249.836 1.00 36.77  ? 341  PHE A CD1   1 
ATOM   2671  C CD2   . PHE A 1 341  ? 233.098 340.408 247.789 1.00 36.77  ? 341  PHE A CD2   1 
ATOM   2672  C CE1   . PHE A 1 341  ? 234.333 339.823 250.180 1.00 36.77  ? 341  PHE A CE1   1 
ATOM   2673  C CE2   . PHE A 1 341  ? 233.354 339.094 248.129 1.00 36.77  ? 341  PHE A CE2   1 
ATOM   2674  C CZ    . PHE A 1 341  ? 233.973 338.801 249.326 1.00 36.77  ? 341  PHE A CZ    1 
ATOM   2675  N N     . SER A 1 342  ? 233.168 344.338 245.681 1.00 40.84  ? 342  SER A N     1 
ATOM   2676  C CA    . SER A 1 342  ? 232.864 344.290 244.255 1.00 40.84  ? 342  SER A CA    1 
ATOM   2677  C C     . SER A 1 342  ? 233.865 345.043 243.383 1.00 40.84  ? 342  SER A C     1 
ATOM   2678  O O     . SER A 1 342  ? 234.668 344.420 242.680 1.00 40.84  ? 342  SER A O     1 
ATOM   2679  C CB    . SER A 1 342  ? 231.457 344.840 244.006 1.00 40.84  ? 342  SER A CB    1 
ATOM   2680  O OG    . SER A 1 342  ? 231.395 346.228 244.284 1.00 40.84  ? 342  SER A OG    1 
ATOM   2681  N N     . GLY A 1 343  ? 233.831 346.375 243.415 1.00 43.77  ? 343  GLY A N     1 
ATOM   2682  C CA    . GLY A 1 343  ? 234.736 347.150 242.586 1.00 43.77  ? 343  GLY A CA    1 
ATOM   2683  C C     . GLY A 1 343  ? 235.138 348.522 243.090 1.00 43.77  ? 343  GLY A C     1 
ATOM   2684  O O     . GLY A 1 343  ? 235.809 349.266 242.369 1.00 43.77  ? 343  GLY A O     1 
ATOM   2685  N N     . ASN A 1 344  ? 234.747 348.880 244.309 1.00 41.50  ? 344  ASN A N     1 
ATOM   2686  C CA    . ASN A 1 344  ? 234.819 350.263 244.766 1.00 41.50  ? 344  ASN A CA    1 
ATOM   2687  C C     . ASN A 1 344  ? 236.083 350.495 245.584 1.00 41.50  ? 344  ASN A C     1 
ATOM   2688  O O     . ASN A 1 344  ? 236.456 349.659 246.413 1.00 41.50  ? 344  ASN A O     1 
ATOM   2689  C CB    . ASN A 1 344  ? 233.581 350.625 245.589 1.00 41.50  ? 344  ASN A CB    1 
ATOM   2690  C CG    . ASN A 1 344  ? 232.589 351.466 244.809 1.00 41.50  ? 344  ASN A CG    1 
ATOM   2691  O OD1   . ASN A 1 344  ? 232.595 351.468 243.578 1.00 41.50  ? 344  ASN A OD1   1 
ATOM   2692  N ND2   . ASN A 1 344  ? 231.727 352.180 245.522 1.00 41.50  ? 344  ASN A ND2   1 
ATOM   2693  N N     . ALA A 1 345  ? 236.742 351.627 245.336 1.00 43.33  ? 345  ALA A N     1 
ATOM   2694  C CA    . ALA A 1 345  ? 237.931 352.032 246.077 1.00 43.33  ? 345  ALA A CA    1 
ATOM   2695  C C     . ALA A 1 345  ? 237.756 353.367 246.782 1.00 43.33  ? 345  ALA A C     1 
ATOM   2696  O O     . ALA A 1 345  ? 238.089 353.484 247.967 1.00 43.33  ? 345  ALA A O     1 
ATOM   2697  C CB    . ALA A 1 345  ? 239.143 352.091 245.134 1.00 43.33  ? 345  ALA A CB    1 
ATOM   2698  N N     . GLU A 1 346  ? 237.248 354.386 246.081 1.00 46.81  ? 346  GLU A N     1 
ATOM   2699  C CA    . GLU A 1 346  ? 237.065 355.699 246.695 1.00 46.81  ? 346  GLU A CA    1 
ATOM   2700  C C     . GLU A 1 346  ? 236.035 355.648 247.817 1.00 46.81  ? 346  GLU A C     1 
ATOM   2701  O O     . GLU A 1 346  ? 236.214 356.280 248.867 1.00 46.81  ? 346  GLU A O     1 
ATOM   2702  C CB    . GLU A 1 346  ? 236.658 356.719 245.630 1.00 46.81  ? 346  GLU A CB    1 
ATOM   2703  C CG    . GLU A 1 346  ? 236.108 358.027 246.180 1.00 46.81  ? 346  GLU A CG    1 
ATOM   2704  C CD    . GLU A 1 346  ? 234.591 358.071 246.178 1.00 46.81  ? 346  GLU A CD    1 
ATOM   2705  O OE1   . GLU A 1 346  ? 233.965 357.026 245.904 1.00 46.81  ? 346  GLU A OE1   1 
ATOM   2706  O OE2   . GLU A 1 346  ? 234.026 359.151 246.450 1.00 46.81  ? 346  GLU A OE2   1 
ATOM   2707  N N     . GLN A 1 347  ? 234.945 354.905 247.608 1.00 40.66  ? 347  GLN A N     1 
ATOM   2708  C CA    . GLN A 1 347  ? 233.936 354.757 248.651 1.00 40.66  ? 347  GLN A CA    1 
ATOM   2709  C C     . GLN A 1 347  ? 234.529 354.109 249.895 1.00 40.66  ? 347  GLN A C     1 
ATOM   2710  O O     . GLN A 1 347  ? 234.199 354.495 251.023 1.00 40.66  ? 347  GLN A O     1 
ATOM   2711  C CB    . GLN A 1 347  ? 232.759 353.935 248.125 1.00 40.66  ? 347  GLN A CB    1 
ATOM   2712  C CG    . GLN A 1 347  ? 231.599 353.808 249.096 1.00 40.66  ? 347  GLN A CG    1 
ATOM   2713  C CD    . GLN A 1 347  ? 230.550 352.819 248.626 1.00 40.66  ? 347  GLN A CD    1 
ATOM   2714  O OE1   . GLN A 1 347  ? 229.641 353.171 247.874 1.00 40.66  ? 347  GLN A OE1   1 
ATOM   2715  N NE2   . GLN A 1 347  ? 230.672 351.572 249.066 1.00 40.66  ? 347  GLN A NE2   1 
ATOM   2716  N N     . VAL A 1 348  ? 235.411 353.126 249.707 1.00 36.28  ? 348  VAL A N     1 
ATOM   2717  C CA    . VAL A 1 348  ? 236.069 352.482 250.840 1.00 36.28  ? 348  VAL A CA    1 
ATOM   2718  C C     . VAL A 1 348  ? 236.893 353.496 251.619 1.00 36.28  ? 348  VAL A C     1 
ATOM   2719  O O     . VAL A 1 348  ? 236.856 353.535 252.854 1.00 36.28  ? 348  VAL A O     1 
ATOM   2720  C CB    . VAL A 1 348  ? 236.938 351.308 250.358 1.00 36.28  ? 348  VAL A CB    1 
ATOM   2721  C CG1   . VAL A 1 348  ? 237.584 350.600 251.541 1.00 36.28  ? 348  VAL A CG1   1 
ATOM   2722  C CG2   . VAL A 1 348  ? 236.110 350.352 249.537 1.00 36.28  ? 348  VAL A CG2   1 
ATOM   2723  N N     . GLN A 1 349  ? 237.653 354.331 250.907 1.00 42.55  ? 349  GLN A N     1 
ATOM   2724  C CA    . GLN A 1 349  ? 238.487 355.327 251.571 1.00 42.55  ? 349  GLN A CA    1 
ATOM   2725  C C     . GLN A 1 349  ? 237.638 356.328 252.345 1.00 42.55  ? 349  GLN A C     1 
ATOM   2726  O O     . GLN A 1 349  ? 237.943 356.659 253.498 1.00 42.55  ? 349  GLN A O     1 
ATOM   2727  C CB    . GLN A 1 349  ? 239.363 356.043 250.543 1.00 42.55  ? 349  GLN A CB    1 
ATOM   2728  C CG    . GLN A 1 349  ? 240.293 357.088 251.137 1.00 42.55  ? 349  GLN A CG    1 
ATOM   2729  C CD    . GLN A 1 349  ? 241.237 356.506 252.171 1.00 42.55  ? 349  GLN A CD    1 
ATOM   2730  O OE1   . GLN A 1 349  ? 241.130 356.801 253.362 1.00 42.55  ? 349  GLN A OE1   1 
ATOM   2731  N NE2   . GLN A 1 349  ? 242.169 355.674 251.720 1.00 42.55  ? 349  GLN A NE2   1 
ATOM   2732  N N     . GLU A 1 350  ? 236.556 356.814 251.730 1.00 42.83  ? 350  GLU A N     1 
ATOM   2733  C CA    . GLU A 1 350  ? 235.719 357.802 252.406 1.00 42.83  ? 350  GLU A CA    1 
ATOM   2734  C C     . GLU A 1 350  ? 235.016 357.199 253.620 1.00 42.83  ? 350  GLU A C     1 
ATOM   2735  O O     . GLU A 1 350  ? 234.918 357.846 254.670 1.00 42.83  ? 350  GLU A O     1 
ATOM   2736  C CB    . GLU A 1 350  ? 234.717 358.413 251.419 1.00 42.83  ? 350  GLU A CB    1 
ATOM   2737  C CG    . GLU A 1 350  ? 233.456 357.603 251.158 1.00 42.83  ? 350  GLU A CG    1 
ATOM   2738  C CD    . GLU A 1 350  ? 232.541 358.258 250.142 1.00 42.83  ? 350  GLU A CD    1 
ATOM   2739  O OE1   . GLU A 1 350  ? 231.830 359.216 250.512 1.00 42.83  ? 350  GLU A OE1   1 
ATOM   2740  O OE2   . GLU A 1 350  ? 232.534 357.816 248.974 1.00 42.83  ? 350  GLU A OE2   1 
ATOM   2741  N N     . TYR A 1 351  ? 234.553 355.950 253.513 1.00 36.96  ? 351  TYR A N     1 
ATOM   2742  C CA    . TYR A 1 351  ? 233.884 355.323 254.647 1.00 36.96  ? 351  TYR A CA    1 
ATOM   2743  C C     . TYR A 1 351  ? 234.869 355.002 255.764 1.00 36.96  ? 351  TYR A C     1 
ATOM   2744  O O     . TYR A 1 351  ? 234.528 355.118 256.946 1.00 36.96  ? 351  TYR A O     1 
ATOM   2745  C CB    . TYR A 1 351  ? 233.144 354.066 254.194 1.00 36.96  ? 351  TYR A CB    1 
ATOM   2746  C CG    . TYR A 1 351  ? 231.695 354.312 253.840 1.00 36.96  ? 351  TYR A CG    1 
ATOM   2747  C CD1   . TYR A 1 351  ? 230.720 354.374 254.828 1.00 36.96  ? 351  TYR A CD1   1 
ATOM   2748  C CD2   . TYR A 1 351  ? 231.301 354.489 252.521 1.00 36.96  ? 351  TYR A CD2   1 
ATOM   2749  C CE1   . TYR A 1 351  ? 229.394 354.601 254.511 1.00 36.96  ? 351  TYR A CE1   1 
ATOM   2750  C CE2   . TYR A 1 351  ? 229.978 354.717 252.194 1.00 36.96  ? 351  TYR A CE2   1 
ATOM   2751  C CZ    . TYR A 1 351  ? 229.029 354.772 253.193 1.00 36.96  ? 351  TYR A CZ    1 
ATOM   2752  O OH    . TYR A 1 351  ? 227.710 354.999 252.872 1.00 36.96  ? 351  TYR A OH    1 
ATOM   2753  N N     . LYS A 1 352  ? 236.096 354.608 255.416 1.00 37.73  ? 352  LYS A N     1 
ATOM   2754  C CA    . LYS A 1 352  ? 237.116 354.391 256.436 1.00 37.73  ? 352  LYS A CA    1 
ATOM   2755  C C     . LYS A 1 352  ? 237.466 355.692 257.145 1.00 37.73  ? 352  LYS A C     1 
ATOM   2756  O O     . LYS A 1 352  ? 237.636 355.714 258.370 1.00 37.73  ? 352  LYS A O     1 
ATOM   2757  C CB    . LYS A 1 352  ? 238.362 353.765 255.808 1.00 37.73  ? 352  LYS A CB    1 
ATOM   2758  C CG    . LYS A 1 352  ? 239.517 353.575 256.777 1.00 37.73  ? 352  LYS A CG    1 
ATOM   2759  C CD    . LYS A 1 352  ? 240.674 352.839 256.120 1.00 37.73  ? 352  LYS A CD    1 
ATOM   2760  C CE    . LYS A 1 352  ? 240.441 351.337 256.116 1.00 37.73  ? 352  LYS A CE    1 
ATOM   2761  N NZ    . LYS A 1 352  ? 240.955 350.700 254.872 1.00 37.73  ? 352  LYS A NZ    1 
ATOM   2762  N N     . GLU A 1 353  ? 237.577 356.789 256.390 1.00 40.98  ? 353  GLU A N     1 
ATOM   2763  C CA    . GLU A 1 353  ? 237.846 358.084 257.005 1.00 40.98  ? 353  GLU A CA    1 
ATOM   2764  C C     . GLU A 1 353  ? 236.711 358.497 257.934 1.00 40.98  ? 353  GLU A C     1 
ATOM   2765  O O     . GLU A 1 353  ? 236.953 359.036 259.021 1.00 40.98  ? 353  GLU A O     1 
ATOM   2766  C CB    . GLU A 1 353  ? 238.071 359.142 255.925 1.00 40.98  ? 353  GLU A CB    1 
ATOM   2767  C CG    . GLU A 1 353  ? 239.439 359.075 255.265 1.00 40.98  ? 353  GLU A CG    1 
ATOM   2768  C CD    . GLU A 1 353  ? 239.626 360.139 254.202 1.00 40.98  ? 353  GLU A CD    1 
ATOM   2769  O OE1   . GLU A 1 353  ? 239.354 361.323 254.490 1.00 40.98  ? 353  GLU A OE1   1 
ATOM   2770  O OE2   . GLU A 1 353  ? 240.046 359.792 253.079 1.00 40.98  ? 353  GLU A OE2   1 
ATOM   2771  N N     . ALA A 1 354  ? 235.464 358.259 257.520 1.00 39.39  ? 354  ALA A N     1 
ATOM   2772  C CA    . ALA A 1 354  ? 234.328 358.575 258.381 1.00 39.39  ? 354  ALA A CA    1 
ATOM   2773  C C     . ALA A 1 354  ? 234.324 357.711 259.638 1.00 39.39  ? 354  ALA A C     1 
ATOM   2774  O O     . ALA A 1 354  ? 234.027 358.200 260.735 1.00 39.39  ? 354  ALA A O     1 
ATOM   2775  C CB    . ALA A 1 354  ? 233.021 358.405 257.608 1.00 39.39  ? 354  ALA A CB    1 
ATOM   2776  N N     . LEU A 1 355  ? 234.651 356.424 259.499 1.00 36.46  ? 355  LEU A N     1 
ATOM   2777  C CA    . LEU A 1 355  ? 234.577 355.504 260.630 1.00 36.46  ? 355  LEU A CA    1 
ATOM   2778  C C     . LEU A 1 355  ? 235.721 355.713 261.614 1.00 36.46  ? 355  LEU A C     1 
ATOM   2779  O O     . LEU A 1 355  ? 235.561 355.442 262.810 1.00 36.46  ? 355  LEU A O     1 
ATOM   2780  C CB    . LEU A 1 355  ? 234.568 354.060 260.126 1.00 36.46  ? 355  LEU A CB    1 
ATOM   2781  C CG    . LEU A 1 355  ? 234.321 352.954 261.155 1.00 36.46  ? 355  LEU A CG    1 
ATOM   2782  C CD1   . LEU A 1 355  ? 232.882 352.982 261.643 1.00 36.46  ? 355  LEU A CD1   1 
ATOM   2783  C CD2   . LEU A 1 355  ? 234.667 351.593 260.572 1.00 36.46  ? 355  LEU A CD2   1 
ATOM   2784  N N     . GLU A 1 356  ? 236.878 356.182 261.139 1.00 37.68  ? 356  GLU A N     1 
ATOM   2785  C CA    . GLU A 1 356  ? 238.011 356.385 262.037 1.00 37.68  ? 356  GLU A CA    1 
ATOM   2786  C C     . GLU A 1 356  ? 237.713 357.441 263.094 1.00 37.68  ? 356  GLU A C     1 
ATOM   2787  O O     . GLU A 1 356  ? 238.262 357.382 264.201 1.00 37.68  ? 356  GLU A O     1 
ATOM   2788  C CB    . GLU A 1 356  ? 239.255 356.772 261.236 1.00 37.68  ? 356  GLU A CB    1 
ATOM   2789  C CG    . GLU A 1 356  ? 239.973 355.597 260.589 1.00 37.68  ? 356  GLU A CG    1 
ATOM   2790  C CD    . GLU A 1 356  ? 240.731 354.745 261.591 1.00 37.68  ? 356  GLU A CD    1 
ATOM   2791  O OE1   . GLU A 1 356  ? 240.936 355.204 262.734 1.00 37.68  ? 356  GLU A OE1   1 
ATOM   2792  O OE2   . GLU A 1 356  ? 241.122 353.614 261.233 1.00 37.68  ? 356  GLU A OE2   1 
ATOM   2793  N N     . ALA A 1 357  ? 236.853 358.410 262.778 1.00 38.57  ? 357  ALA A N     1 
ATOM   2794  C CA    . ALA A 1 357  ? 236.530 359.463 263.733 1.00 38.57  ? 357  ALA A CA    1 
ATOM   2795  C C     . ALA A 1 357  ? 235.598 358.981 264.838 1.00 38.57  ? 357  ALA A C     1 
ATOM   2796  O O     . ALA A 1 357  ? 235.667 359.490 265.963 1.00 38.57  ? 357  ALA A O     1 
ATOM   2797  C CB    . ALA A 1 357  ? 235.906 360.656 263.008 1.00 38.57  ? 357  ALA A CB    1 
ATOM   2798  N N     . VAL A 1 358  ? 234.730 358.012 264.549 1.00 36.37  ? 358  VAL A N     1 
ATOM   2799  C CA    . VAL A 1 358  ? 233.741 357.555 265.519 1.00 36.37  ? 358  VAL A CA    1 
ATOM   2800  C C     . VAL A 1 358  ? 234.328 356.442 266.377 1.00 36.37  ? 358  VAL A C     1 
ATOM   2801  O O     . VAL A 1 358  ? 233.665 355.927 267.284 1.00 36.37  ? 358  VAL A O     1 
ATOM   2802  C CB    . VAL A 1 358  ? 232.449 357.090 264.821 1.00 36.37  ? 358  VAL A CB    1 
ATOM   2803  C CG1   . VAL A 1 358  ? 232.016 358.105 263.775 1.00 36.37  ? 358  VAL A CG1   1 
ATOM   2804  C CG2   . VAL A 1 358  ? 232.644 355.717 264.194 1.00 36.37  ? 358  VAL A CG2   1 
ATOM   2805  N N     . LEU A 1 359  ? 235.574 356.068 266.103 1.00 39.82  ? 359  LEU A N     1 
ATOM   2806  C CA    . LEU A 1 359  ? 236.256 355.045 266.880 1.00 39.82  ? 359  LEU A CA    1 
ATOM   2807  C C     . LEU A 1 359  ? 236.779 355.635 268.184 1.00 39.82  ? 359  LEU A C     1 
ATOM   2808  O O     . LEU A 1 359  ? 237.297 356.754 268.220 1.00 39.82  ? 359  LEU A O     1 
ATOM   2809  C CB    . LEU A 1 359  ? 237.410 354.435 266.082 1.00 39.82  ? 359  LEU A CB    1 
ATOM   2810  C CG    . LEU A 1 359  ? 237.054 353.275 265.150 1.00 39.82  ? 359  LEU A CG    1 
ATOM   2811  C CD1   . LEU A 1 359  ? 238.195 352.990 264.185 1.00 39.82  ? 359  LEU A CD1   1 
ATOM   2812  C CD2   . LEU A 1 359  ? 236.698 352.030 265.948 1.00 39.82  ? 359  LEU A CD2   1 
ATOM   2813  N N     . ILE A 1 360  ? 236.637 354.866 269.261 1.00 40.08  ? 360  ILE A N     1 
ATOM   2814  C CA    . ILE A 1 360  ? 237.054 355.282 270.595 1.00 40.08  ? 360  ILE A CA    1 
ATOM   2815  C C     . ILE A 1 360  ? 238.129 354.322 271.087 1.00 40.08  ? 360  ILE A C     1 
ATOM   2816  O O     . ILE A 1 360  ? 238.003 353.102 270.931 1.00 40.08  ? 360  ILE A O     1 
ATOM   2817  C CB    . ILE A 1 360  ? 235.865 355.344 271.572 1.00 40.08  ? 360  ILE A CB    1 
ATOM   2818  C CG1   . ILE A 1 360  ? 235.081 354.031 271.568 1.00 40.08  ? 360  ILE A CG1   1 
ATOM   2819  C CG2   . ILE A 1 360  ? 234.950 356.510 271.227 1.00 40.08  ? 360  ILE A CG2   1 
ATOM   2820  C CD1   . ILE A 1 360  ? 234.058 353.945 272.674 1.00 40.08  ? 360  ILE A CD1   1 
ATOM   2821  N N     . LYS A 1 361  ? 239.190 354.879 271.665 1.00 42.16  ? 361  LYS A N     1 
ATOM   2822  C CA    . LYS A 1 361  ? 240.347 354.087 272.056 1.00 42.16  ? 361  LYS A CA    1 
ATOM   2823  C C     . LYS A 1 361  ? 240.051 353.250 273.297 1.00 42.16  ? 361  LYS A C     1 
ATOM   2824  O O     . LYS A 1 361  ? 239.097 353.504 274.036 1.00 42.16  ? 361  LYS A O     1 
ATOM   2825  C CB    . LYS A 1 361  ? 241.546 354.998 272.316 1.00 42.16  ? 361  LYS A CB    1 
ATOM   2826  C CG    . LYS A 1 361  ? 242.842 354.506 271.700 1.00 42.16  ? 361  LYS A CG    1 
ATOM   2827  C CD    . LYS A 1 361  ? 242.968 354.959 270.254 1.00 42.16  ? 361  LYS A CD    1 
ATOM   2828  C CE    . LYS A 1 361  ? 244.352 354.667 269.701 1.00 42.16  ? 361  LYS A CE    1 
ATOM   2829  N NZ    . LYS A 1 361  ? 244.379 354.738 268.214 1.00 42.16  ? 361  LYS A NZ    1 
ATOM   2830  N N     . GLY A 1 362  ? 240.890 352.239 273.517 1.00 51.90  ? 362  GLY A N     1 
ATOM   2831  C CA    . GLY A 1 362  ? 240.762 351.374 274.674 1.00 51.90  ? 362  GLY A CA    1 
ATOM   2832  C C     . GLY A 1 362  ? 242.060 351.206 275.438 1.00 51.90  ? 362  GLY A C     1 
ATOM   2833  O O     . GLY A 1 362  ? 242.899 352.112 275.452 1.00 51.90  ? 362  GLY A O     1 
ATOM   2834  N N     . LYS A 1 363  ? 242.234 350.054 276.081 1.00 54.90  ? 363  LYS A N     1 
ATOM   2835  C CA    . LYS A 1 363  ? 243.451 349.792 276.837 1.00 54.90  ? 363  LYS A CA    1 
ATOM   2836  C C     . LYS A 1 363  ? 244.649 349.664 275.904 1.00 54.90  ? 363  LYS A C     1 
ATOM   2837  O O     . LYS A 1 363  ? 244.576 349.011 274.859 1.00 54.90  ? 363  LYS A O     1 
ATOM   2838  C CB    . LYS A 1 363  ? 243.296 348.518 277.667 1.00 54.90  ? 363  LYS A CB    1 
ATOM   2839  C CG    . LYS A 1 363  ? 244.356 348.344 278.743 1.00 54.90  ? 363  LYS A CG    1 
ATOM   2840  C CD    . LYS A 1 363  ? 243.883 348.891 280.079 1.00 54.90  ? 363  LYS A CD    1 
ATOM   2841  C CE    . LYS A 1 363  ? 243.026 347.876 280.818 1.00 54.90  ? 363  LYS A CE    1 
ATOM   2842  N NZ    . LYS A 1 363  ? 242.758 348.294 282.222 1.00 54.90  ? 363  LYS A NZ    1 
ATOM   2843  N N     . ASN A 1 364  ? 245.760 350.292 276.295 1.00 57.65  ? 364  ASN A N     1 
ATOM   2844  C CA    . ASN A 1 364  ? 246.997 350.288 275.510 1.00 57.65  ? 364  ASN A CA    1 
ATOM   2845  C C     . ASN A 1 364  ? 246.775 350.839 274.103 1.00 57.65  ? 364  ASN A C     1 
ATOM   2846  O O     . ASN A 1 364  ? 247.444 350.431 273.151 1.00 57.65  ? 364  ASN A O     1 
ATOM   2847  C CB    . ASN A 1 364  ? 247.614 348.887 275.447 1.00 57.65  ? 364  ASN A CB    1 
ATOM   2848  C CG    . ASN A 1 364  ? 249.106 348.917 275.175 1.00 57.65  ? 364  ASN A CG    1 
ATOM   2849  O OD1   . ASN A 1 364  ? 249.715 349.985 275.111 1.00 57.65  ? 364  ASN A OD1   1 
ATOM   2850  N ND2   . ASN A 1 364  ? 249.702 347.742 275.012 1.00 57.65  ? 364  ASN A ND2   1 
ATOM   2851  N N     . GLY A 1 365  ? 245.837 351.772 273.966 1.00 50.47  ? 365  GLY A N     1 
ATOM   2852  C CA    . GLY A 1 365  ? 245.554 352.371 272.671 1.00 50.47  ? 365  GLY A CA    1 
ATOM   2853  C C     . GLY A 1 365  ? 245.026 351.402 271.636 1.00 50.47  ? 365  GLY A C     1 
ATOM   2854  O O     . GLY A 1 365  ? 245.426 351.469 270.467 1.00 50.47  ? 365  GLY A O     1 
ATOM   2855  N N     . VAL A 1 366  ? 244.135 350.502 272.036 1.00 43.83  ? 366  VAL A N     1 
ATOM   2856  C CA    . VAL A 1 366  ? 243.547 349.522 271.125 1.00 43.83  ? 366  VAL A CA    1 
ATOM   2857  C C     . VAL A 1 366  ? 242.266 350.120 270.551 1.00 43.83  ? 366  VAL A C     1 
ATOM   2858  O O     . VAL A 1 366  ? 241.488 350.729 271.305 1.00 43.83  ? 366  VAL A O     1 
ATOM   2859  C CB    . VAL A 1 366  ? 243.276 348.184 271.828 1.00 43.83  ? 366  VAL A CB    1 
ATOM   2860  C CG1   . VAL A 1 366  ? 242.213 348.320 272.916 1.00 43.83  ? 366  VAL A CG1   1 
ATOM   2861  C CG2   . VAL A 1 366  ? 242.870 347.125 270.816 1.00 43.83  ? 366  VAL A CG2   1 
ATOM   2862  N N     . PRO A 1 367  ? 242.037 350.031 269.241 1.00 39.02  ? 367  PRO A N     1 
ATOM   2863  C CA    . PRO A 1 367  ? 240.751 350.475 268.693 1.00 39.02  ? 367  PRO A CA    1 
ATOM   2864  C C     . PRO A 1 367  ? 239.610 349.608 269.204 1.00 39.02  ? 367  PRO A C     1 
ATOM   2865  O O     . PRO A 1 367  ? 239.745 348.391 269.347 1.00 39.02  ? 367  PRO A O     1 
ATOM   2866  C CB    . PRO A 1 367  ? 240.938 350.328 267.178 1.00 39.02  ? 367  PRO A CB    1 
ATOM   2867  C CG    . PRO A 1 367  ? 242.418 350.301 266.968 1.00 39.02  ? 367  PRO A CG    1 
ATOM   2868  C CD    . PRO A 1 367  ? 242.990 349.649 268.187 1.00 39.02  ? 367  PRO A CD    1 
ATOM   2869  N N     . LEU A 1 368  ? 238.477 350.248 269.479 1.00 44.14  ? 368  LEU A N     1 
ATOM   2870  C CA    . LEU A 1 368  ? 237.275 349.558 269.925 1.00 44.14  ? 368  LEU A CA    1 
ATOM   2871  C C     . LEU A 1 368  ? 236.060 350.171 269.248 1.00 44.14  ? 368  LEU A C     1 
ATOM   2872  O O     . LEU A 1 368  ? 235.974 351.392 269.091 1.00 44.14  ? 368  LEU A O     1 
ATOM   2873  C CB    . LEU A 1 368  ? 237.118 349.626 271.450 1.00 44.14  ? 368  LEU A CB    1 
ATOM   2874  C CG    . LEU A 1 368  ? 238.126 348.823 272.274 1.00 44.14  ? 368  LEU A CG    1 
ATOM   2875  C CD1   . LEU A 1 368  ? 238.000 349.154 273.753 1.00 44.14  ? 368  LEU A CD1   1 
ATOM   2876  C CD2   . LEU A 1 368  ? 237.948 347.331 272.037 1.00 44.14  ? 368  LEU A CD2   1 
ATOM   2877  N N     . LEU A 1 369  ? 235.119 349.315 268.851 1.00 64.40  ? 369  LEU A N     1 
ATOM   2878  C CA    . LEU A 1 369  ? 233.919 349.764 268.162 1.00 64.40  ? 369  LEU A CA    1 
ATOM   2879  C C     . LEU A 1 369  ? 232.759 349.802 269.143 1.00 64.40  ? 369  LEU A C     1 
ATOM   2880  O O     . LEU A 1 369  ? 232.320 348.739 269.607 1.00 64.40  ? 369  LEU A O     1 
ATOM   2881  C CB    . LEU A 1 369  ? 233.596 348.842 266.989 1.00 64.40  ? 369  LEU A CB    1 
ATOM   2882  C CG    . LEU A 1 369  ? 232.703 349.417 265.889 1.00 64.40  ? 369  LEU A CG    1 
ATOM   2883  C CD1   . LEU A 1 369  ? 233.246 349.058 264.515 1.00 64.40  ? 369  LEU A CD1   1 
ATOM   2884  C CD2   . LEU A 1 369  ? 231.272 348.926 266.045 1.00 64.40  ? 369  LEU A CD2   1 
ATOM   2885  N N     . PRO A 1 370  ? 232.240 350.976 269.496 1.00 64.40  ? 370  PRO A N     1 
ATOM   2886  C CA    . PRO A 1 370  ? 231.084 351.028 270.396 1.00 64.40  ? 370  PRO A CA    1 
ATOM   2887  C C     . PRO A 1 370  ? 229.842 350.446 269.741 1.00 64.40  ? 370  PRO A C     1 
ATOM   2888  O O     . PRO A 1 370  ? 229.680 350.477 268.519 1.00 64.40  ? 370  PRO A O     1 
ATOM   2889  C CB    . PRO A 1 370  ? 230.916 352.526 270.676 1.00 64.40  ? 370  PRO A CB    1 
ATOM   2890  C CG    . PRO A 1 370  ? 231.555 353.201 269.510 1.00 64.40  ? 370  PRO A CG    1 
ATOM   2891  C CD    . PRO A 1 370  ? 232.685 352.315 269.077 1.00 64.40  ? 370  PRO A CD    1 
ATOM   2892  N N     . GLU A 1 371  ? 228.958 349.900 270.581 1.00 54.85  ? 371  GLU A N     1 
ATOM   2893  C CA    . GLU A 1 371  ? 227.751 349.259 270.069 1.00 54.85  ? 371  GLU A CA    1 
ATOM   2894  C C     . GLU A 1 371  ? 226.836 350.262 269.377 1.00 54.85  ? 371  GLU A C     1 
ATOM   2895  O O     . GLU A 1 371  ? 226.333 349.997 268.278 1.00 54.85  ? 371  GLU A O     1 
ATOM   2896  C CB    . GLU A 1 371  ? 227.011 348.552 271.204 1.00 54.85  ? 371  GLU A CB    1 
ATOM   2897  C CG    . GLU A 1 371  ? 225.702 347.903 270.782 1.00 54.85  ? 371  GLU A CG    1 
ATOM   2898  C CD    . GLU A 1 371  ? 225.165 346.939 271.822 1.00 54.85  ? 371  GLU A CD    1 
ATOM   2899  O OE1   . GLU A 1 371  ? 225.636 346.986 272.978 1.00 54.85  ? 371  GLU A OE1   1 
ATOM   2900  O OE2   . GLU A 1 371  ? 224.273 346.133 271.483 1.00 54.85  ? 371  GLU A OE2   1 
ATOM   2901  N N     . LEU A 1 372  ? 226.616 351.419 269.995 1.00 64.40  ? 372  LEU A N     1 
ATOM   2902  C CA    . LEU A 1 372  ? 225.710 352.422 269.448 1.00 64.40  ? 372  LEU A CA    1 
ATOM   2903  C C     . LEU A 1 372  ? 225.937 353.737 270.182 1.00 64.40  ? 372  LEU A C     1 
ATOM   2904  O O     . LEU A 1 372  ? 226.527 353.774 271.265 1.00 64.40  ? 372  LEU A O     1 
ATOM   2905  C CB    . LEU A 1 372  ? 224.244 351.979 269.553 1.00 64.40  ? 372  LEU A CB    1 
ATOM   2906  C CG    . LEU A 1 372  ? 223.473 352.124 270.871 1.00 64.40  ? 372  LEU A CG    1 
ATOM   2907  C CD1   . LEU A 1 372  ? 222.077 351.540 270.720 1.00 64.40  ? 372  LEU A CD1   1 
ATOM   2908  C CD2   . LEU A 1 372  ? 224.188 351.468 272.046 1.00 64.40  ? 372  LEU A CD2   1 
ATOM   2909  N N     . TYR A 1 373  ? 225.457 354.817 269.573 1.00 50.04  ? 373  TYR A N     1 
ATOM   2910  C CA    . TYR A 1 373  ? 225.517 356.143 270.179 1.00 50.04  ? 373  TYR A CA    1 
ATOM   2911  C C     . TYR A 1 373  ? 224.116 356.608 270.560 1.00 50.04  ? 373  TYR A C     1 
ATOM   2912  O O     . TYR A 1 373  ? 223.168 356.430 269.796 1.00 50.04  ? 373  TYR A O     1 
ATOM   2913  C CB    . TYR A 1 373  ? 226.167 357.149 269.226 1.00 50.04  ? 373  TYR A CB    1 
ATOM   2914  C CG    . TYR A 1 373  ? 227.677 357.076 269.178 1.00 50.04  ? 373  TYR A CG    1 
ATOM   2915  C CD1   . TYR A 1 373  ? 228.324 356.037 268.523 1.00 50.04  ? 373  TYR A CD1   1 
ATOM   2916  C CD2   . TYR A 1 373  ? 228.456 358.051 269.788 1.00 50.04  ? 373  TYR A CD2   1 
ATOM   2917  C CE1   . TYR A 1 373  ? 229.704 355.971 268.476 1.00 50.04  ? 373  TYR A CE1   1 
ATOM   2918  C CE2   . TYR A 1 373  ? 229.835 357.993 269.748 1.00 50.04  ? 373  TYR A CE2   1 
ATOM   2919  C CZ    . TYR A 1 373  ? 230.454 356.952 269.092 1.00 50.04  ? 373  TYR A CZ    1 
ATOM   2920  O OH    . TYR A 1 373  ? 231.829 356.894 269.051 1.00 50.04  ? 373  TYR A OH    1 
HETATM 2921  N N     . SEP A 1 374  ? 223.988 357.205 271.740 1.00 67.66  ? 374  SEP A N     1 
HETATM 2922  C CA    . SEP A 1 374  ? 222.682 357.623 272.241 1.00 67.66  ? 374  SEP A CA    1 
HETATM 2923  C CB    . SEP A 1 374  ? 222.328 356.846 273.512 1.00 67.66  ? 374  SEP A CB    1 
HETATM 2924  O OG    . SEP A 1 374  ? 221.050 357.219 274.000 1.00 67.66  ? 374  SEP A OG    1 
HETATM 2925  C C     . SEP A 1 374  ? 222.623 359.122 272.520 1.00 67.66  ? 374  SEP A C     1 
HETATM 2926  O O     . SEP A 1 374  ? 223.602 359.721 272.964 1.00 67.66  ? 374  SEP A O     1 
HETATM 2927  P P     . SEP A 1 374  ? 220.824 356.626 275.479 1.00 67.66  ? 374  SEP A P     1 
HETATM 2928  O O1P   . SEP A 1 374  ? 219.338 356.971 275.990 1.00 67.66  ? 374  SEP A O1P   1 
HETATM 2929  O O2P   . SEP A 1 374  ? 221.044 355.030 275.471 1.00 67.66  ? 374  SEP A O2P   1 
HETATM 2930  O O3P   . SEP A 1 374  ? 221.887 357.307 276.473 1.00 67.66  ? 374  SEP A O3P   1 
ATOM   2931  N N     . VAL A 1 375  ? 221.464 359.718 272.259 1.00 59.93  ? 375  VAL A N     1 
ATOM   2932  C CA    . VAL A 1 375  ? 221.250 361.140 272.496 1.00 59.93  ? 375  VAL A CA    1 
ATOM   2933  C C     . VAL A 1 375  ? 221.089 361.409 273.990 1.00 59.93  ? 375  VAL A C     1 
ATOM   2934  O O     . VAL A 1 375  ? 220.329 360.715 274.666 1.00 59.93  ? 375  VAL A O     1 
ATOM   2935  C CB    . VAL A 1 375  ? 220.024 361.653 271.713 1.00 59.93  ? 375  VAL A CB    1 
ATOM   2936  C CG1   . VAL A 1 375  ? 219.849 363.150 271.907 1.00 59.93  ? 375  VAL A CG1   1 
ATOM   2937  C CG2   . VAL A 1 375  ? 220.160 361.321 270.235 1.00 59.93  ? 375  VAL A CG2   1 
ATOM   2938  N N     . PRO A 1 376  ? 221.810 362.402 274.505 1.00 58.15  ? 376  PRO A N     1 
ATOM   2939  C CA    . PRO A 1 376  ? 221.666 362.773 275.919 1.00 58.15  ? 376  PRO A CA    1 
ATOM   2940  C C     . PRO A 1 376  ? 220.246 363.214 276.224 1.00 58.15  ? 376  PRO A C     1 
ATOM   2941  O O     . PRO A 1 376  ? 219.589 363.848 275.384 1.00 58.15  ? 376  PRO A O     1 
ATOM   2942  C CB    . PRO A 1 376  ? 222.660 363.932 276.088 1.00 58.15  ? 376  PRO A CB    1 
ATOM   2943  C CG    . PRO A 1 376  ? 223.631 363.773 274.969 1.00 58.15  ? 376  PRO A CG    1 
ATOM   2944  C CD    . PRO A 1 376  ? 222.860 363.182 273.829 1.00 58.15  ? 376  PRO A CD    1 
ATOM   2945  N N     . PRO A 1 377  ? 219.733 362.886 277.412 1.00 60.20  ? 377  PRO A N     1 
ATOM   2946  C CA    . PRO A 1 377  ? 218.345 363.258 277.740 1.00 60.20  ? 377  PRO A CA    1 
ATOM   2947  C C     . PRO A 1 377  ? 218.096 364.755 277.741 1.00 60.20  ? 377  PRO A C     1 
ATOM   2948  O O     . PRO A 1 377  ? 216.983 365.187 277.414 1.00 60.20  ? 377  PRO A O     1 
ATOM   2949  C CB    . PRO A 1 377  ? 218.141 362.650 279.135 1.00 60.20  ? 377  PRO A CB    1 
ATOM   2950  C CG    . PRO A 1 377  ? 219.518 362.498 279.695 1.00 60.20  ? 377  PRO A CG    1 
ATOM   2951  C CD    . PRO A 1 377  ? 220.405 362.197 278.526 1.00 60.20  ? 377  PRO A CD    1 
ATOM   2952  N N     . ASP A 1 378  ? 219.091 365.564 278.112 1.00 66.79  ? 378  ASP A N     1 
ATOM   2953  C CA    . ASP A 1 378  ? 218.890 367.009 278.155 1.00 66.79  ? 378  ASP A CA    1 
ATOM   2954  C C     . ASP A 1 378  ? 218.674 367.586 276.761 1.00 66.79  ? 378  ASP A C     1 
ATOM   2955  O O     . ASP A 1 378  ? 217.801 368.438 276.562 1.00 66.79  ? 378  ASP A O     1 
ATOM   2956  C CB    . ASP A 1 378  ? 220.077 367.683 278.844 1.00 66.79  ? 378  ASP A CB    1 
ATOM   2957  C CG    . ASP A 1 378  ? 221.409 367.275 278.245 1.00 66.79  ? 378  ASP A CG    1 
ATOM   2958  O OD1   . ASP A 1 378  ? 221.743 367.760 277.144 1.00 66.79  ? 378  ASP A OD1   1 
ATOM   2959  O OD2   . ASP A 1 378  ? 222.123 366.467 278.876 1.00 66.79  ? 378  ASP A OD2   1 
ATOM   2960  N N     . ARG A 1 379  ? 219.459 367.136 275.783 1.00 69.59  ? 379  ARG A N     1 
ATOM   2961  C CA    . ARG A 1 379  ? 219.378 367.662 274.419 1.00 69.59  ? 379  ARG A CA    1 
ATOM   2962  C C     . ARG A 1 379  ? 218.490 366.774 273.543 1.00 69.59  ? 379  ARG A C     1 
ATOM   2963  O O     . ARG A 1 379  ? 218.918 366.202 272.542 1.00 69.59  ? 379  ARG A O     1 
ATOM   2964  C CB    . ARG A 1 379  ? 220.776 367.805 273.828 1.00 69.59  ? 379  ARG A CB    1 
ATOM   2965  C CG    . ARG A 1 379  ? 221.460 369.120 274.169 1.00 69.59  ? 379  ARG A CG    1 
ATOM   2966  C CD    . ARG A 1 379  ? 222.972 368.965 274.204 1.00 69.59  ? 379  ARG A CD    1 
ATOM   2967  N NE    . ARG A 1 379  ? 223.545 368.896 272.865 1.00 69.59  ? 379  ARG A NE    1 
ATOM   2968  C CZ    . ARG A 1 379  ? 224.841 368.985 272.600 1.00 69.59  ? 379  ARG A CZ    1 
ATOM   2969  N NH1   . ARG A 1 379  ? 225.734 369.148 273.563 1.00 69.59  ? 379  ARG A NH1   1 
ATOM   2970  N NH2   . ARG A 1 379  ? 225.252 368.909 271.337 1.00 69.59  ? 379  ARG A NH2   1 
ATOM   2971  N N     . VAL A 1 380  ? 217.226 366.672 273.941 1.00 72.27  ? 380  VAL A N     1 
ATOM   2972  C CA    . VAL A 1 380  ? 216.238 365.897 273.201 1.00 72.27  ? 380  VAL A CA    1 
ATOM   2973  C C     . VAL A 1 380  ? 215.406 366.781 272.279 1.00 72.27  ? 380  VAL A C     1 
ATOM   2974  O O     . VAL A 1 380  ? 215.194 366.439 271.115 1.00 72.27  ? 380  VAL A O     1 
ATOM   2975  C CB    . VAL A 1 380  ? 215.341 365.106 274.177 1.00 72.27  ? 380  VAL A CB    1 
ATOM   2976  C CG1   . VAL A 1 380  ? 214.007 364.762 273.528 1.00 72.27  ? 380  VAL A CG1   1 
ATOM   2977  C CG2   . VAL A 1 380  ? 216.049 363.842 274.637 1.00 72.27  ? 380  VAL A CG2   1 
ATOM   2978  N N     . ASP A 1 381  ? 214.936 367.925 272.783 1.00 84.05  ? 381  ASP A N     1 
ATOM   2979  C CA    . ASP A 1 381  ? 214.132 368.824 271.961 1.00 84.05  ? 381  ASP A CA    1 
ATOM   2980  C C     . ASP A 1 381  ? 214.948 369.401 270.810 1.00 84.05  ? 381  ASP A C     1 
ATOM   2981  O O     . ASP A 1 381  ? 214.424 369.601 269.707 1.00 84.05  ? 381  ASP A O     1 
ATOM   2982  C CB    . ASP A 1 381  ? 213.553 369.946 272.823 1.00 84.05  ? 381  ASP A CB    1 
ATOM   2983  C CG    . ASP A 1 381  ? 212.628 369.429 273.907 1.00 84.05  ? 381  ASP A CG    1 
ATOM   2984  O OD1   . ASP A 1 381  ? 213.132 368.866 274.902 1.00 84.05  ? 381  ASP A OD1   1 
ATOM   2985  O OD2   . ASP A 1 381  ? 211.397 369.586 273.764 1.00 84.05  ? 381  ASP A OD2   1 
ATOM   2986  N N     . GLU A 1 382  ? 216.231 369.683 271.051 1.00 87.09  ? 382  GLU A N     1 
ATOM   2987  C CA    . GLU A 1 382  ? 217.075 370.252 270.005 1.00 87.09  ? 382  GLU A CA    1 
ATOM   2988  C C     . GLU A 1 382  ? 217.215 369.299 268.826 1.00 87.09  ? 382  GLU A C     1 
ATOM   2989  O O     . GLU A 1 382  ? 217.179 369.726 267.666 1.00 87.09  ? 382  GLU A O     1 
ATOM   2990  C CB    . GLU A 1 382  ? 218.449 370.605 270.575 1.00 87.09  ? 382  GLU A CB    1 
ATOM   2991  C CG    . GLU A 1 382  ? 219.322 371.415 269.631 1.00 87.09  ? 382  GLU A CG    1 
ATOM   2992  C CD    . GLU A 1 382  ? 220.656 371.789 270.248 1.00 87.09  ? 382  GLU A CD    1 
ATOM   2993  O OE1   . GLU A 1 382  ? 220.763 371.770 271.492 1.00 87.09  ? 382  GLU A OE1   1 
ATOM   2994  O OE2   . GLU A 1 382  ? 221.597 372.100 269.488 1.00 87.09  ? 382  GLU A OE2   1 
ATOM   2995  N N     . GLU A 1 383  ? 217.383 368.003 269.101 1.00 84.86  ? 383  GLU A N     1 
ATOM   2996  C CA    . GLU A 1 383  ? 217.509 367.031 268.019 1.00 84.86  ? 383  GLU A CA    1 
ATOM   2997  C C     . GLU A 1 383  ? 216.222 366.930 267.209 1.00 84.86  ? 383  GLU A C     1 
ATOM   2998  O O     . GLU A 1 383  ? 216.264 366.822 265.979 1.00 84.86  ? 383  GLU A O     1 
ATOM   2999  C CB    . GLU A 1 383  ? 217.902 365.664 268.581 1.00 84.86  ? 383  GLU A CB    1 
ATOM   3000  C CG    . GLU A 1 383  ? 218.003 364.552 267.539 1.00 84.86  ? 383  GLU A CG    1 
ATOM   3001  C CD    . GLU A 1 383  ? 219.292 364.586 266.730 1.00 84.86  ? 383  GLU A CD    1 
ATOM   3002  O OE1   . GLU A 1 383  ? 219.843 365.683 266.501 1.00 84.86  ? 383  GLU A OE1   1 
ATOM   3003  O OE2   . GLU A 1 383  ? 219.757 363.501 266.321 1.00 84.86  ? 383  GLU A OE2   1 
ATOM   3004  N N     . TYR A 1 384  ? 215.068 366.951 267.880 1.00 89.60  ? 384  TYR A N     1 
ATOM   3005  C CA    . TYR A 1 384  ? 213.804 366.896 267.153 1.00 89.60  ? 384  TYR A CA    1 
ATOM   3006  C C     . TYR A 1 384  ? 213.612 368.141 266.295 1.00 89.60  ? 384  TYR A C     1 
ATOM   3007  O O     . TYR A 1 384  ? 213.219 368.044 265.126 1.00 89.60  ? 384  TYR A O     1 
ATOM   3008  C CB    . TYR A 1 384  ? 212.640 366.717 268.131 1.00 89.60  ? 384  TYR A CB    1 
ATOM   3009  C CG    . TYR A 1 384  ? 211.328 366.319 267.481 1.00 89.60  ? 384  TYR A CG    1 
ATOM   3010  C CD1   . TYR A 1 384  ? 210.617 367.211 266.686 1.00 89.60  ? 384  TYR A CD1   1 
ATOM   3011  C CD2   . TYR A 1 384  ? 210.808 365.043 267.653 1.00 89.60  ? 384  TYR A CD2   1 
ATOM   3012  C CE1   . TYR A 1 384  ? 209.426 366.847 266.089 1.00 89.60  ? 384  TYR A CE1   1 
ATOM   3013  C CE2   . TYR A 1 384  ? 209.616 364.669 267.060 1.00 89.60  ? 384  TYR A CE2   1 
ATOM   3014  C CZ    . TYR A 1 384  ? 208.931 365.576 266.279 1.00 89.60  ? 384  TYR A CZ    1 
ATOM   3015  O OH    . TYR A 1 384  ? 207.745 365.211 265.685 1.00 89.60  ? 384  TYR A OH    1 
ATOM   3016  N N     . GLN A 1 385  ? 213.890 369.320 266.855 1.00 91.51  ? 385  GLN A N     1 
ATOM   3017  C CA    . GLN A 1 385  ? 213.765 370.552 266.082 1.00 91.51  ? 385  GLN A CA    1 
ATOM   3018  C C     . GLN A 1 385  ? 214.857 370.668 265.025 1.00 91.51  ? 385  GLN A C     1 
ATOM   3019  O O     . GLN A 1 385  ? 214.601 371.147 263.915 1.00 91.51  ? 385  GLN A O     1 
ATOM   3020  C CB    . GLN A 1 385  ? 213.788 371.763 267.016 1.00 91.51  ? 385  GLN A CB    1 
ATOM   3021  C CG    . GLN A 1 385  ? 212.410 372.329 267.354 1.00 91.51  ? 385  GLN A CG    1 
ATOM   3022  C CD    . GLN A 1 385  ? 211.495 371.325 268.036 1.00 91.51  ? 385  GLN A CD    1 
ATOM   3023  O OE1   . GLN A 1 385  ? 211.950 370.353 268.637 1.00 91.51  ? 385  GLN A OE1   1 
ATOM   3024  N NE2   . GLN A 1 385  ? 210.191 371.560 267.942 1.00 91.51  ? 385  GLN A NE2   1 
ATOM   3025  N N     . ASN A 1 386  ? 216.077 370.236 265.348 1.00 88.06  ? 386  ASN A N     1 
ATOM   3026  C CA    . ASN A 1 386  ? 217.214 370.274 264.428 1.00 88.06  ? 386  ASN A CA    1 
ATOM   3027  C C     . ASN A 1 386  ? 217.782 368.866 264.307 1.00 88.06  ? 386  ASN A C     1 
ATOM   3028  O O     . ASN A 1 386  ? 218.620 368.452 265.125 1.00 88.06  ? 386  ASN A O     1 
ATOM   3029  C CB    . ASN A 1 386  ? 218.277 371.261 264.908 1.00 88.06  ? 386  ASN A CB    1 
ATOM   3030  C CG    . ASN A 1 386  ? 218.693 372.240 263.828 1.00 88.06  ? 386  ASN A CG    1 
ATOM   3031  O OD1   . ASN A 1 386  ? 218.943 371.854 262.686 1.00 88.06  ? 386  ASN A OD1   1 
ATOM   3032  N ND2   . ASN A 1 386  ? 218.768 373.517 264.185 1.00 88.06  ? 386  ASN A ND2   1 
ATOM   3033  N N     . PRO A 1 387  ? 217.348 368.091 263.313 1.00 85.46  ? 387  PRO A N     1 
ATOM   3034  C CA    . PRO A 1 387  ? 217.826 366.709 263.193 1.00 85.46  ? 387  PRO A CA    1 
ATOM   3035  C C     . PRO A 1 387  ? 219.320 366.642 262.913 1.00 85.46  ? 387  PRO A C     1 
ATOM   3036  O O     . PRO A 1 387  ? 219.879 367.475 262.196 1.00 85.46  ? 387  PRO A O     1 
ATOM   3037  C CB    . PRO A 1 387  ? 217.012 366.151 262.019 1.00 85.46  ? 387  PRO A CB    1 
ATOM   3038  C CG    . PRO A 1 387  ? 216.594 367.353 261.238 1.00 85.46  ? 387  PRO A CG    1 
ATOM   3039  C CD    . PRO A 1 387  ? 216.408 368.454 262.239 1.00 85.46  ? 387  PRO A CD    1 
ATOM   3040  N N     . HIS A 1 388  ? 219.958 365.622 263.488 1.00 79.13  ? 388  HIS A N     1 
ATOM   3041  C CA    . HIS A 1 388  ? 221.382 365.346 263.287 1.00 79.13  ? 388  HIS A CA    1 
ATOM   3042  C C     . HIS A 1 388  ? 222.237 366.574 263.600 1.00 79.13  ? 388  HIS A C     1 
ATOM   3043  O O     . HIS A 1 388  ? 223.081 366.995 262.807 1.00 79.13  ? 388  HIS A O     1 
ATOM   3044  C CB    . HIS A 1 388  ? 221.642 364.844 261.866 1.00 79.13  ? 388  HIS A CB    1 
ATOM   3045  C CG    . HIS A 1 388  ? 221.089 363.479 261.596 1.00 79.13  ? 388  HIS A CG    1 
ATOM   3046  N ND1   . HIS A 1 388  ? 220.449 362.731 262.561 1.00 79.13  ? 388  HIS A ND1   1 
ATOM   3047  C CD2   . HIS A 1 388  ? 221.080 362.727 260.470 1.00 79.13  ? 388  HIS A CD2   1 
ATOM   3048  C CE1   . HIS A 1 388  ? 220.069 361.577 262.041 1.00 79.13  ? 388  HIS A CE1   1 
ATOM   3049  N NE2   . HIS A 1 388  ? 220.440 361.549 260.774 1.00 79.13  ? 388  HIS A NE2   1 
ATOM   3050  N N     . THR A 1 389  ? 222.010 367.153 264.778 1.00 74.41  ? 389  THR A N     1 
ATOM   3051  C CA    . THR A 1 389  ? 222.730 368.359 265.170 1.00 74.41  ? 389  THR A CA    1 
ATOM   3052  C C     . THR A 1 389  ? 223.425 368.192 266.516 1.00 74.41  ? 389  THR A C     1 
ATOM   3053  O O     . THR A 1 389  ? 224.532 368.705 266.714 1.00 74.41  ? 389  THR A O     1 
ATOM   3054  C CB    . THR A 1 389  ? 221.778 369.556 265.216 1.00 74.41  ? 389  THR A CB    1 
ATOM   3055  O OG1   . THR A 1 389  ? 220.871 369.488 264.109 1.00 74.41  ? 389  THR A OG1   1 
ATOM   3056  C CG2   . THR A 1 389  ? 222.558 370.860 265.145 1.00 74.41  ? 389  THR A CG2   1 
ATOM   3057  N N     . VAL A 1 390  ? 222.792 367.479 267.447 1.00 68.53  ? 390  VAL A N     1 
ATOM   3058  C CA    . VAL A 1 390  ? 223.351 367.301 268.783 1.00 68.53  ? 390  VAL A CA    1 
ATOM   3059  C C     . VAL A 1 390  ? 224.456 366.255 268.734 1.00 68.53  ? 390  VAL A C     1 
ATOM   3060  O O     . VAL A 1 390  ? 224.598 365.530 267.743 1.00 68.53  ? 390  VAL A O     1 
ATOM   3061  C CB    . VAL A 1 390  ? 222.267 366.904 269.801 1.00 68.53  ? 390  VAL A CB    1 
ATOM   3062  C CG1   . VAL A 1 390  ? 221.375 368.095 270.124 1.00 68.53  ? 390  VAL A CG1   1 
ATOM   3063  C CG2   . VAL A 1 390  ? 221.454 365.730 269.285 1.00 68.53  ? 390  VAL A CG2   1 
ATOM   3064  N N     . ASP A 1 391  ? 225.242 366.170 269.802 1.00 63.79  ? 391  ASP A N     1 
ATOM   3065  C CA    . ASP A 1 391  ? 226.328 365.206 269.915 1.00 63.79  ? 391  ASP A CA    1 
ATOM   3066  C C     . ASP A 1 391  ? 225.910 364.087 270.858 1.00 63.79  ? 391  ASP A C     1 
ATOM   3067  O O     . ASP A 1 391  ? 225.450 364.350 271.975 1.00 63.79  ? 391  ASP A O     1 
ATOM   3068  C CB    . ASP A 1 391  ? 227.608 365.877 270.418 1.00 63.79  ? 391  ASP A CB    1 
ATOM   3069  C CG    . ASP A 1 391  ? 228.287 366.712 269.350 1.00 63.79  ? 391  ASP A CG    1 
ATOM   3070  O OD1   . ASP A 1 391  ? 227.608 367.103 268.377 1.00 63.79  ? 391  ASP A OD1   1 
ATOM   3071  O OD2   . ASP A 1 391  ? 229.500 366.979 269.483 1.00 63.79  ? 391  ASP A OD2   1 
ATOM   3072  N N     . ARG A 1 392  ? 226.072 362.846 270.408 1.00 54.37  ? 392  ARG A N     1 
ATOM   3073  C CA    . ARG A 1 392  ? 225.680 361.684 271.186 1.00 54.37  ? 392  ARG A CA    1 
ATOM   3074  C C     . ARG A 1 392  ? 226.855 361.187 272.026 1.00 54.37  ? 392  ARG A C     1 
ATOM   3075  O O     . ARG A 1 392  ? 227.969 361.713 271.963 1.00 54.37  ? 392  ARG A O     1 
ATOM   3076  C CB    . ARG A 1 392  ? 225.152 360.585 270.266 1.00 54.37  ? 392  ARG A CB    1 
ATOM   3077  C CG    . ARG A 1 392  ? 223.850 360.938 269.564 1.00 54.37  ? 392  ARG A CG    1 
ATOM   3078  C CD    . ARG A 1 392  ? 223.987 360.815 268.055 1.00 54.37  ? 392  ARG A CD    1 
ATOM   3079  N NE    . ARG A 1 392  ? 222.753 361.157 267.357 1.00 54.37  ? 392  ARG A NE    1 
ATOM   3080  C CZ    . ARG A 1 392  ? 221.708 360.349 267.240 1.00 54.37  ? 392  ARG A CZ    1 
ATOM   3081  N NH1   . ARG A 1 392  ? 221.712 359.133 267.760 1.00 54.37  ? 392  ARG A NH1   1 
ATOM   3082  N NH2   . ARG A 1 392  ? 220.632 360.771 266.581 1.00 54.37  ? 392  ARG A NH2   1 
ATOM   3083  N N     . VAL A 1 393  ? 226.604 360.155 272.825 1.00 48.26  ? 393  VAL A N     1 
ATOM   3084  C CA    . VAL A 1 393  ? 227.630 359.588 273.698 1.00 48.26  ? 393  VAL A CA    1 
ATOM   3085  C C     . VAL A 1 393  ? 227.671 358.082 273.484 1.00 48.26  ? 393  VAL A C     1 
ATOM   3086  O O     . VAL A 1 393  ? 226.647 357.452 273.174 1.00 48.26  ? 393  VAL A O     1 
ATOM   3087  C CB    . VAL A 1 393  ? 227.370 359.929 275.184 1.00 48.26  ? 393  VAL A CB    1 
ATOM   3088  C CG1   . VAL A 1 393  ? 227.739 361.377 275.469 1.00 48.26  ? 393  VAL A CG1   1 
ATOM   3089  C CG2   . VAL A 1 393  ? 225.916 359.662 275.542 1.00 48.26  ? 393  VAL A CG2   1 
ATOM   3090  N N     . PRO A 1 394  ? 228.848 357.473 273.630 1.00 50.43  ? 394  PRO A N     1 
ATOM   3091  C CA    . PRO A 1 394  ? 228.946 356.016 273.483 1.00 50.43  ? 394  PRO A CA    1 
ATOM   3092  C C     . PRO A 1 394  ? 228.178 355.286 274.574 1.00 50.43  ? 394  PRO A C     1 
ATOM   3093  O O     . PRO A 1 394  ? 228.094 355.736 275.718 1.00 50.43  ? 394  PRO A O     1 
ATOM   3094  C CB    . PRO A 1 394  ? 230.453 355.744 273.588 1.00 50.43  ? 394  PRO A CB    1 
ATOM   3095  C CG    . PRO A 1 394  ? 231.110 357.055 273.317 1.00 50.43  ? 394  PRO A CG    1 
ATOM   3096  C CD    . PRO A 1 394  ? 230.166 358.104 273.808 1.00 50.43  ? 394  PRO A CD    1 
ATOM   3097  N N     . MET A 1 395  ? 227.622 354.135 274.204 1.00 56.90  ? 395  MET A N     1 
ATOM   3098  C CA    . MET A 1 395  ? 226.885 353.300 275.143 1.00 56.90  ? 395  MET A CA    1 
ATOM   3099  C C     . MET A 1 395  ? 226.811 351.888 274.581 1.00 56.90  ? 395  MET A C     1 
ATOM   3100  O O     . MET A 1 395  ? 227.189 351.636 273.434 1.00 56.90  ? 395  MET A O     1 
ATOM   3101  C CB    . MET A 1 395  ? 225.483 353.859 275.416 1.00 56.90  ? 395  MET A CB    1 
ATOM   3102  C CG    . MET A 1 395  ? 224.960 353.571 276.817 1.00 56.90  ? 395  MET A CG    1 
ATOM   3103  S SD    . MET A 1 395  ? 223.723 354.761 277.371 1.00 56.90  ? 395  MET A SD    1 
ATOM   3104  C CE    . MET A 1 395  ? 224.746 356.202 277.659 1.00 56.90  ? 395  MET A CE    1 
ATOM   3105  N N     . GLY A 1 396  ? 226.326 350.970 275.411 1.00 56.23  ? 396  GLY A N     1 
ATOM   3106  C CA    . GLY A 1 396  ? 226.258 349.576 275.035 1.00 56.23  ? 396  GLY A CA    1 
ATOM   3107  C C     . GLY A 1 396  ? 227.567 348.853 275.285 1.00 56.23  ? 396  GLY A C     1 
ATOM   3108  O O     . GLY A 1 396  ? 228.472 349.340 275.971 1.00 56.23  ? 396  GLY A O     1 
ATOM   3109  N N     . LYS A 1 397  ? 227.660 347.655 274.711 1.00 53.05  ? 397  LYS A N     1 
ATOM   3110  C CA    . LYS A 1 397  ? 228.865 346.848 274.853 1.00 53.05  ? 397  LYS A CA    1 
ATOM   3111  C C     . LYS A 1 397  ? 230.037 347.507 274.137 1.00 53.05  ? 397  LYS A C     1 
ATOM   3112  O O     . LYS A 1 397  ? 230.099 347.504 272.903 1.00 53.05  ? 397  LYS A O     1 
ATOM   3113  C CB    . LYS A 1 397  ? 228.639 345.435 274.310 1.00 53.05  ? 397  LYS A CB    1 
ATOM   3114  C CG    . LYS A 1 397  ? 227.416 344.729 274.871 1.00 53.05  ? 397  LYS A CG    1 
ATOM   3115  C CD    . LYS A 1 397  ? 226.684 343.955 273.786 1.00 53.05  ? 397  LYS A CD    1 
ATOM   3116  C CE    . LYS A 1 397  ? 225.492 343.200 274.350 1.00 53.05  ? 397  LYS A CE    1 
ATOM   3117  N NZ    . LYS A 1 397  ? 224.608 342.686 273.269 1.00 53.05  ? 397  LYS A NZ    1 
ATOM   3118  N N     . LEU A 1 398  ? 230.965 348.079 274.905 1.00 50.43  ? 398  LEU A N     1 
ATOM   3119  C CA    . LEU A 1 398  ? 232.132 348.718 274.300 1.00 50.43  ? 398  LEU A CA    1 
ATOM   3120  C C     . LEU A 1 398  ? 232.981 347.737 273.500 1.00 50.43  ? 398  LEU A C     1 
ATOM   3121  O O     . LEU A 1 398  ? 233.360 348.071 272.364 1.00 50.43  ? 398  LEU A O     1 
ATOM   3122  C CB    . LEU A 1 398  ? 232.945 349.439 275.384 1.00 50.43  ? 398  LEU A CB    1 
ATOM   3123  C CG    . LEU A 1 398  ? 234.432 349.681 275.116 1.00 50.43  ? 398  LEU A CG    1 
ATOM   3124  C CD1   . LEU A 1 398  ? 234.622 350.680 273.986 1.00 50.43  ? 398  LEU A CD1   1 
ATOM   3125  C CD2   . LEU A 1 398  ? 235.133 350.159 276.379 1.00 50.43  ? 398  LEU A CD2   1 
ATOM   3126  N N     . PRO A 1 399  ? 233.320 346.532 274.002 1.00 53.14  ? 399  PRO A N     1 
ATOM   3127  C CA    . PRO A 1 399  ? 234.013 345.573 273.105 1.00 53.14  ? 399  PRO A CA    1 
ATOM   3128  C C     . PRO A 1 399  ? 233.028 344.807 272.226 1.00 53.14  ? 399  PRO A C     1 
ATOM   3129  O O     . PRO A 1 399  ? 232.781 343.606 272.401 1.00 53.14  ? 399  PRO A O     1 
ATOM   3130  C CB    . PRO A 1 399  ? 234.751 344.656 274.088 1.00 53.14  ? 399  PRO A CB    1 
ATOM   3131  C CG    . PRO A 1 399  ? 234.146 344.867 275.410 1.00 53.14  ? 399  PRO A CG    1 
ATOM   3132  C CD    . PRO A 1 399  ? 233.351 346.115 275.416 1.00 53.14  ? 399  PRO A CD    1 
ATOM   3133  N N     . HIS A 1 400  ? 232.439 345.508 271.257 1.00 64.40  ? 400  HIS A N     1 
ATOM   3134  C CA    . HIS A 1 400  ? 231.488 344.875 270.351 1.00 64.40  ? 400  HIS A CA    1 
ATOM   3135  C C     . HIS A 1 400  ? 232.216 343.908 269.427 1.00 64.40  ? 400  HIS A C     1 
ATOM   3136  O O     . HIS A 1 400  ? 232.880 344.329 268.474 1.00 64.40  ? 400  HIS A O     1 
ATOM   3137  C CB    . HIS A 1 400  ? 230.728 345.925 269.538 1.00 64.40  ? 400  HIS A CB    1 
ATOM   3138  C CG    . HIS A 1 400  ? 229.431 345.431 268.975 1.00 64.40  ? 400  HIS A CG    1 
ATOM   3139  N ND1   . HIS A 1 400  ? 228.956 345.825 267.742 1.00 64.40  ? 400  HIS A ND1   1 
ATOM   3140  C CD2   . HIS A 1 400  ? 228.510 344.575 269.477 1.00 64.40  ? 400  HIS A CD2   1 
ATOM   3141  C CE1   . HIS A 1 400  ? 227.798 345.233 267.509 1.00 64.40  ? 400  HIS A CE1   1 
ATOM   3142  N NE2   . HIS A 1 400  ? 227.505 344.469 268.546 1.00 64.40  ? 400  HIS A NE2   1 
ATOM   3143  N N     . MET A 1 401  ? 232.096 342.607 269.707 1.00 50.39  ? 401  MET A N     1 
ATOM   3144  C CA    . MET A 1 401  ? 232.850 341.611 268.952 1.00 50.39  ? 401  MET A CA    1 
ATOM   3145  C C     . MET A 1 401  ? 232.423 341.572 267.491 1.00 50.39  ? 401  MET A C     1 
ATOM   3146  O O     . MET A 1 401  ? 233.266 341.440 266.597 1.00 50.39  ? 401  MET A O     1 
ATOM   3147  C CB    . MET A 1 401  ? 232.693 340.236 269.602 1.00 50.39  ? 401  MET A CB    1 
ATOM   3148  C CG    . MET A 1 401  ? 233.741 339.943 270.663 1.00 50.39  ? 401  MET A CG    1 
ATOM   3149  S SD    . MET A 1 401  ? 233.461 338.392 271.536 1.00 50.39  ? 401  MET A SD    1 
ATOM   3150  C CE    . MET A 1 401  ? 233.374 338.977 273.227 1.00 50.39  ? 401  MET A CE    1 
ATOM   3151  N N     . TRP A 1 402  ? 231.120 341.682 267.227 1.00 64.40  ? 402  TRP A N     1 
ATOM   3152  C CA    . TRP A 1 402  ? 230.629 341.669 265.852 1.00 64.40  ? 402  TRP A CA    1 
ATOM   3153  C C     . TRP A 1 402  ? 231.217 342.826 265.050 1.00 64.40  ? 402  TRP A C     1 
ATOM   3154  O O     . TRP A 1 402  ? 231.833 342.625 263.993 1.00 64.40  ? 402  TRP A O     1 
ATOM   3155  C CB    . TRP A 1 402  ? 229.099 341.732 265.861 1.00 64.40  ? 402  TRP A CB    1 
ATOM   3156  C CG    . TRP A 1 402  ? 228.434 341.509 264.531 1.00 64.40  ? 402  TRP A CG    1 
ATOM   3157  C CD1   . TRP A 1 402  ? 229.040 341.364 263.317 1.00 64.40  ? 402  TRP A CD1   1 
ATOM   3158  C CD2   . TRP A 1 402  ? 227.024 341.416 264.288 1.00 64.40  ? 402  TRP A CD2   1 
ATOM   3159  N NE1   . TRP A 1 402  ? 228.096 341.183 262.335 1.00 64.40  ? 402  TRP A NE1   1 
ATOM   3160  C CE2   . TRP A 1 402  ? 226.851 341.210 262.905 1.00 64.40  ? 402  TRP A CE2   1 
ATOM   3161  C CE3   . TRP A 1 402  ? 225.892 341.484 265.106 1.00 64.40  ? 402  TRP A CE3   1 
ATOM   3162  C CZ2   . TRP A 1 402  ? 225.592 341.073 262.323 1.00 64.40  ? 402  TRP A CZ2   1 
ATOM   3163  C CZ3   . TRP A 1 402  ? 224.644 341.348 264.526 1.00 64.40  ? 402  TRP A CZ3   1 
ATOM   3164  C CH2   . TRP A 1 402  ? 224.504 341.144 263.148 1.00 64.40  ? 402  TRP A CH2   1 
ATOM   3165  N N     . GLY A 1 403  ? 231.060 344.050 265.558 1.00 51.77  ? 403  GLY A N     1 
ATOM   3166  C CA    . GLY A 1 403  ? 231.538 345.212 264.829 1.00 51.77  ? 403  GLY A CA    1 
ATOM   3167  C C     . GLY A 1 403  ? 233.048 345.249 264.709 1.00 51.77  ? 403  GLY A C     1 
ATOM   3168  O O     . GLY A 1 403  ? 233.587 345.565 263.646 1.00 51.77  ? 403  GLY A O     1 
ATOM   3169  N N     . GLN A 1 404  ? 233.752 344.929 265.798 1.00 39.09  ? 404  GLN A N     1 
ATOM   3170  C CA    . GLN A 1 404  ? 235.210 344.938 265.762 1.00 39.09  ? 404  GLN A CA    1 
ATOM   3171  C C     . GLN A 1 404  ? 235.746 343.883 264.802 1.00 39.09  ? 404  GLN A C     1 
ATOM   3172  O O     . GLN A 1 404  ? 236.682 344.147 264.039 1.00 39.09  ? 404  GLN A O     1 
ATOM   3173  C CB    . GLN A 1 404  ? 235.773 344.723 267.166 1.00 39.09  ? 404  GLN A CB    1 
ATOM   3174  C CG    . GLN A 1 404  ? 237.280 344.550 267.206 1.00 39.09  ? 404  GLN A CG    1 
ATOM   3175  C CD    . GLN A 1 404  ? 238.008 345.854 267.462 1.00 39.09  ? 404  GLN A CD    1 
ATOM   3176  O OE1   . GLN A 1 404  ? 237.571 346.674 268.268 1.00 39.09  ? 404  GLN A OE1   1 
ATOM   3177  N NE2   . GLN A 1 404  ? 239.128 346.051 266.775 1.00 39.09  ? 404  GLN A NE2   1 
ATOM   3178  N N     . SER A 1 405  ? 235.164 342.681 264.823 1.00 39.16  ? 405  SER A N     1 
ATOM   3179  C CA    . SER A 1 405  ? 235.596 341.630 263.908 1.00 39.16  ? 405  SER A CA    1 
ATOM   3180  C C     . SER A 1 405  ? 235.340 342.020 262.459 1.00 39.16  ? 405  SER A C     1 
ATOM   3181  O O     . SER A 1 405  ? 236.195 341.806 261.589 1.00 39.16  ? 405  SER A O     1 
ATOM   3182  C CB    . SER A 1 405  ? 234.886 340.319 264.244 1.00 39.16  ? 405  SER A CB    1 
ATOM   3183  O OG    . SER A 1 405  ? 234.947 339.411 263.158 1.00 39.16  ? 405  SER A OG    1 
ATOM   3184  N N     . LEU A 1 406  ? 234.168 342.597 262.177 1.00 64.40  ? 406  LEU A N     1 
ATOM   3185  C CA    . LEU A 1 406  ? 233.871 343.010 260.810 1.00 64.40  ? 406  LEU A CA    1 
ATOM   3186  C C     . LEU A 1 406  ? 234.809 344.122 260.353 1.00 64.40  ? 406  LEU A C     1 
ATOM   3187  O O     . LEU A 1 406  ? 235.269 344.123 259.205 1.00 64.40  ? 406  LEU A O     1 
ATOM   3188  C CB    . LEU A 1 406  ? 232.413 343.449 260.703 1.00 64.40  ? 406  LEU A CB    1 
ATOM   3189  C CG    . LEU A 1 406  ? 231.415 342.301 260.545 1.00 64.40  ? 406  LEU A CG    1 
ATOM   3190  C CD1   . LEU A 1 406  ? 230.059 342.832 260.134 1.00 64.40  ? 406  LEU A CD1   1 
ATOM   3191  C CD2   . LEU A 1 406  ? 231.919 341.275 259.539 1.00 64.40  ? 406  LEU A CD2   1 
ATOM   3192  N N     . TYR A 1 407  ? 235.110 345.074 261.240 1.00 36.68  ? 407  TYR A N     1 
ATOM   3193  C CA    . TYR A 1 407  ? 236.037 346.146 260.892 1.00 36.68  ? 407  TYR A CA    1 
ATOM   3194  C C     . TYR A 1 407  ? 237.439 345.603 260.644 1.00 36.68  ? 407  TYR A C     1 
ATOM   3195  O O     . TYR A 1 407  ? 238.131 346.054 259.725 1.00 36.68  ? 407  TYR A O     1 
ATOM   3196  C CB    . TYR A 1 407  ? 236.049 347.204 261.996 1.00 36.68  ? 407  TYR A CB    1 
ATOM   3197  C CG    . TYR A 1 407  ? 237.399 347.842 262.236 1.00 36.68  ? 407  TYR A CG    1 
ATOM   3198  C CD1   . TYR A 1 407  ? 237.876 348.842 261.397 1.00 36.68  ? 407  TYR A CD1   1 
ATOM   3199  C CD2   . TYR A 1 407  ? 238.193 347.454 263.308 1.00 36.68  ? 407  TYR A CD2   1 
ATOM   3200  C CE1   . TYR A 1 407  ? 239.107 349.430 261.614 1.00 36.68  ? 407  TYR A CE1   1 
ATOM   3201  C CE2   . TYR A 1 407  ? 239.426 348.036 263.533 1.00 36.68  ? 407  TYR A CE2   1 
ATOM   3202  C CZ    . TYR A 1 407  ? 239.878 349.024 262.683 1.00 36.68  ? 407  TYR A CZ    1 
ATOM   3203  O OH    . TYR A 1 407  ? 241.104 349.607 262.903 1.00 36.68  ? 407  TYR A OH    1 
ATOM   3204  N N     . ILE A 1 408  ? 237.876 344.638 261.457 1.00 41.89  ? 408  ILE A N     1 
ATOM   3205  C CA    . ILE A 1 408  ? 239.190 344.033 261.257 1.00 41.89  ? 408  ILE A CA    1 
ATOM   3206  C C     . ILE A 1 408  ? 239.246 343.310 259.918 1.00 41.89  ? 408  ILE A C     1 
ATOM   3207  O O     . ILE A 1 408  ? 240.229 343.424 259.175 1.00 41.89  ? 408  ILE A O     1 
ATOM   3208  C CB    . ILE A 1 408  ? 239.530 343.090 262.427 1.00 41.89  ? 408  ILE A CB    1 
ATOM   3209  C CG1   . ILE A 1 408  ? 239.892 343.895 263.676 1.00 41.89  ? 408  ILE A CG1   1 
ATOM   3210  C CG2   . ILE A 1 408  ? 240.667 342.150 262.052 1.00 41.89  ? 408  ILE A CG2   1 
ATOM   3211  C CD1   . ILE A 1 408  ? 239.777 343.106 264.962 1.00 41.89  ? 408  ILE A CD1   1 
ATOM   3212  N N     . LEU A 1 409  ? 238.194 342.557 259.587 1.00 29.30  ? 409  LEU A N     1 
ATOM   3213  C CA    . LEU A 1 409  ? 238.160 341.861 258.304 1.00 29.30  ? 409  LEU A CA    1 
ATOM   3214  C C     . LEU A 1 409  ? 238.181 342.847 257.141 1.00 29.30  ? 409  LEU A C     1 
ATOM   3215  O O     . LEU A 1 409  ? 238.897 342.641 256.152 1.00 29.30  ? 409  LEU A O     1 
ATOM   3216  C CB    . LEU A 1 409  ? 236.926 340.963 258.226 1.00 29.30  ? 409  LEU A CB    1 
ATOM   3217  C CG    . LEU A 1 409  ? 236.782 340.112 256.963 1.00 29.30  ? 409  LEU A CG    1 
ATOM   3218  C CD1   . LEU A 1 409  ? 237.903 339.088 256.874 1.00 29.30  ? 409  LEU A CD1   1 
ATOM   3219  C CD2   . LEU A 1 409  ? 235.423 339.430 256.925 1.00 29.30  ? 409  LEU A CD2   1 
ATOM   3220  N N     . GLY A 1 410  ? 237.405 343.929 257.245 1.00 33.65  ? 410  GLY A N     1 
ATOM   3221  C CA    . GLY A 1 410  ? 237.402 344.929 256.191 1.00 33.65  ? 410  GLY A CA    1 
ATOM   3222  C C     . GLY A 1 410  ? 238.747 345.607 256.021 1.00 33.65  ? 410  GLY A C     1 
ATOM   3223  O O     . GLY A 1 410  ? 239.202 345.831 254.897 1.00 33.65  ? 410  GLY A O     1 
ATOM   3224  N N     . SER A 1 411  ? 239.402 345.946 257.134 1.00 30.11  ? 411  SER A N     1 
ATOM   3225  C CA    . SER A 1 411  ? 240.722 346.562 257.059 1.00 30.11  ? 411  SER A CA    1 
ATOM   3226  C C     . SER A 1 411  ? 241.743 345.605 256.457 1.00 30.11  ? 411  SER A C     1 
ATOM   3227  O O     . SER A 1 411  ? 242.586 346.014 255.649 1.00 30.11  ? 411  SER A O     1 
ATOM   3228  C CB    . SER A 1 411  ? 241.167 347.019 258.448 1.00 30.11  ? 411  SER A CB    1 
ATOM   3229  O OG    . SER A 1 411  ? 242.569 347.214 258.496 1.00 30.11  ? 411  SER A OG    1 
ATOM   3230  N N     . LEU A 1 412  ? 241.684 344.326 256.837 1.00 29.00  ? 412  LEU A N     1 
ATOM   3231  C CA    . LEU A 1 412  ? 242.599 343.341 256.271 1.00 29.00  ? 412  LEU A CA    1 
ATOM   3232  C C     . LEU A 1 412  ? 242.387 343.192 254.771 1.00 29.00  ? 412  LEU A C     1 
ATOM   3233  O O     . LEU A 1 412  ? 243.354 343.084 254.007 1.00 29.00  ? 412  LEU A O     1 
ATOM   3234  C CB    . LEU A 1 412  ? 242.423 341.996 256.975 1.00 29.00  ? 412  LEU A CB    1 
ATOM   3235  C CG    . LEU A 1 412  ? 243.676 341.128 257.114 1.00 29.00  ? 412  LEU A CG    1 
ATOM   3236  C CD1   . LEU A 1 412  ? 244.551 341.625 258.253 1.00 29.00  ? 412  LEU A CD1   1 
ATOM   3237  C CD2   . LEU A 1 412  ? 243.299 339.669 257.319 1.00 29.00  ? 412  LEU A CD2   1 
ATOM   3238  N N     . MET A 1 413  ? 241.127 343.177 254.330 1.00 34.15  ? 413  MET A N     1 
ATOM   3239  C CA    . MET A 1 413  ? 240.852 343.079 252.900 1.00 34.15  ? 413  MET A CA    1 
ATOM   3240  C C     . MET A 1 413  ? 241.311 344.330 252.157 1.00 34.15  ? 413  MET A C     1 
ATOM   3241  O O     . MET A 1 413  ? 241.842 344.237 251.045 1.00 34.15  ? 413  MET A O     1 
ATOM   3242  C CB    . MET A 1 413  ? 239.363 342.828 252.668 1.00 34.15  ? 413  MET A CB    1 
ATOM   3243  C CG    . MET A 1 413  ? 239.068 341.465 252.070 1.00 34.15  ? 413  MET A CG    1 
ATOM   3244  S SD    . MET A 1 413  ? 237.309 341.140 251.871 1.00 34.15  ? 413  MET A SD    1 
ATOM   3245  C CE    . MET A 1 413  ? 237.315 339.351 251.868 1.00 34.15  ? 413  MET A CE    1 
ATOM   3246  N N     . ALA A 1 414  ? 241.109 345.508 252.753 1.00 32.80  ? 414  ALA A N     1 
ATOM   3247  C CA    . ALA A 1 414  ? 241.517 346.749 252.103 1.00 32.80  ? 414  ALA A CA    1 
ATOM   3248  C C     . ALA A 1 414  ? 243.034 346.853 251.999 1.00 32.80  ? 414  ALA A C     1 
ATOM   3249  O O     . ALA A 1 414  ? 243.558 347.374 251.007 1.00 32.80  ? 414  ALA A O     1 
ATOM   3250  C CB    . ALA A 1 414  ? 240.947 347.949 252.859 1.00 32.80  ? 414  ALA A CB    1 
ATOM   3251  N N     . GLU A 1 415  ? 243.755 346.369 253.013 1.00 38.44  ? 415  GLU A N     1 
ATOM   3252  C CA    . GLU A 1 415  ? 245.212 346.446 252.994 1.00 38.44  ? 415  GLU A CA    1 
ATOM   3253  C C     . GLU A 1 415  ? 245.830 345.554 251.924 1.00 38.44  ? 415  GLU A C     1 
ATOM   3254  O O     . GLU A 1 415  ? 247.024 345.688 251.637 1.00 38.44  ? 415  GLU A O     1 
ATOM   3255  C CB    . GLU A 1 415  ? 245.778 346.080 254.368 1.00 38.44  ? 415  GLU A CB    1 
ATOM   3256  C CG    . GLU A 1 415  ? 245.577 347.149 255.432 1.00 38.44  ? 415  GLU A CG    1 
ATOM   3257  C CD    . GLU A 1 415  ? 246.551 348.305 255.298 1.00 38.44  ? 415  GLU A CD    1 
ATOM   3258  O OE1   . GLU A 1 415  ? 247.468 348.221 254.455 1.00 38.44  ? 415  GLU A OE1   1 
ATOM   3259  O OE2   . GLU A 1 415  ? 246.398 349.299 256.039 1.00 38.44  ? 415  GLU A OE2   1 
ATOM   3260  N N     . GLY A 1 416  ? 245.051 344.649 251.331 1.00 33.60  ? 416  GLY A N     1 
ATOM   3261  C CA    . GLY A 1 416  ? 245.541 343.781 250.284 1.00 33.60  ? 416  GLY A CA    1 
ATOM   3262  C C     . GLY A 1 416  ? 246.098 342.454 250.750 1.00 33.60  ? 416  GLY A C     1 
ATOM   3263  O O     . GLY A 1 416  ? 246.469 341.628 249.905 1.00 33.60  ? 416  GLY A O     1 
ATOM   3264  N N     . PHE A 1 417  ? 246.175 342.220 252.062 1.00 34.10  ? 417  PHE A N     1 
ATOM   3265  C CA    . PHE A 1 417  ? 246.672 340.943 252.561 1.00 34.10  ? 417  PHE A CA    1 
ATOM   3266  C C     . PHE A 1 417  ? 245.731 339.791 252.238 1.00 34.10  ? 417  PHE A C     1 
ATOM   3267  O O     . PHE A 1 417  ? 246.152 338.630 252.282 1.00 34.10  ? 417  PHE A O     1 
ATOM   3268  C CB    . PHE A 1 417  ? 246.901 341.020 254.071 1.00 34.10  ? 417  PHE A CB    1 
ATOM   3269  C CG    . PHE A 1 417  ? 247.943 342.022 254.476 1.00 34.10  ? 417  PHE A CG    1 
ATOM   3270  C CD1   . PHE A 1 417  ? 249.268 341.847 254.115 1.00 34.10  ? 417  PHE A CD1   1 
ATOM   3271  C CD2   . PHE A 1 417  ? 247.598 343.138 255.219 1.00 34.10  ? 417  PHE A CD2   1 
ATOM   3272  C CE1   . PHE A 1 417  ? 250.230 342.768 254.486 1.00 34.10  ? 417  PHE A CE1   1 
ATOM   3273  C CE2   . PHE A 1 417  ? 248.554 344.062 255.594 1.00 34.10  ? 417  PHE A CE2   1 
ATOM   3274  C CZ    . PHE A 1 417  ? 249.872 343.877 255.226 1.00 34.10  ? 417  PHE A CZ    1 
ATOM   3275  N N     . LEU A 1 418  ? 244.472 340.081 251.917 1.00 35.12  ? 418  LEU A N     1 
ATOM   3276  C CA    . LEU A 1 418  ? 243.488 339.060 251.597 1.00 35.12  ? 418  LEU A CA    1 
ATOM   3277  C C     . LEU A 1 418  ? 242.754 339.439 250.319 1.00 35.12  ? 418  LEU A C     1 
ATOM   3278  O O     . LEU A 1 418  ? 242.601 340.620 249.997 1.00 35.12  ? 418  LEU A O     1 
ATOM   3279  C CB    . LEU A 1 418  ? 242.485 338.870 252.742 1.00 35.12  ? 418  LEU A CB    1 
ATOM   3280  C CG    . LEU A 1 418  ? 242.019 337.438 253.004 1.00 35.12  ? 418  LEU A CG    1 
ATOM   3281  C CD1   . LEU A 1 418  ? 243.140 336.611 253.612 1.00 35.12  ? 418  LEU A CD1   1 
ATOM   3282  C CD2   . LEU A 1 418  ? 240.802 337.439 253.911 1.00 35.12  ? 418  LEU A CD2   1 
ATOM   3283  N N     . ALA A 1 419  ? 242.303 338.422 249.595 1.00 37.89  ? 419  ALA A N     1 
ATOM   3284  C CA    . ALA A 1 419  ? 241.601 338.590 248.335 1.00 37.89  ? 419  ALA A CA    1 
ATOM   3285  C C     . ALA A 1 419  ? 240.125 338.247 248.486 1.00 37.89  ? 419  ALA A C     1 
ATOM   3286  O O     . ALA A 1 419  ? 239.746 337.446 249.347 1.00 37.89  ? 419  ALA A O     1 
ATOM   3287  C CB    . ALA A 1 419  ? 242.226 337.704 247.248 1.00 37.89  ? 419  ALA A CB    1 
ATOM   3288  N N     . PRO A 1 420  ? 239.256 338.851 247.670 1.00 38.56  ? 420  PRO A N     1 
ATOM   3289  C CA    . PRO A 1 420  ? 237.826 338.507 247.746 1.00 38.56  ? 420  PRO A CA    1 
ATOM   3290  C C     . PRO A 1 420  ? 237.537 337.047 247.450 1.00 38.56  ? 420  PRO A C     1 
ATOM   3291  O O     . PRO A 1 420  ? 236.536 336.511 247.943 1.00 38.56  ? 420  PRO A O     1 
ATOM   3292  C CB    . PRO A 1 420  ? 237.185 339.432 246.701 1.00 38.56  ? 420  PRO A CB    1 
ATOM   3293  C CG    . PRO A 1 420  ? 238.158 340.551 246.524 1.00 38.56  ? 420  PRO A CG    1 
ATOM   3294  C CD    . PRO A 1 420  ? 239.515 339.952 246.726 1.00 38.56  ? 420  PRO A CD    1 
ATOM   3295  N N     . GLY A 1 421  ? 238.380 336.385 246.661 1.00 36.89  ? 421  GLY A N     1 
ATOM   3296  C CA    . GLY A 1 421  ? 238.181 334.991 246.326 1.00 36.89  ? 421  GLY A CA    1 
ATOM   3297  C C     . GLY A 1 421  ? 238.591 333.996 247.385 1.00 36.89  ? 421  GLY A C     1 
ATOM   3298  O O     . GLY A 1 421  ? 238.364 332.795 247.212 1.00 36.89  ? 421  GLY A O     1 
ATOM   3299  N N     . GLU A 1 422  ? 239.191 334.456 248.483 1.00 39.28  ? 422  GLU A N     1 
ATOM   3300  C CA    . GLU A 1 422  ? 239.601 333.568 249.564 1.00 39.28  ? 422  GLU A CA    1 
ATOM   3301  C C     . GLU A 1 422  ? 238.453 333.280 250.526 1.00 39.28  ? 422  GLU A C     1 
ATOM   3302  O O     . GLU A 1 422  ? 238.186 332.118 250.850 1.00 39.28  ? 422  GLU A O     1 
ATOM   3303  C CB    . GLU A 1 422  ? 240.787 334.175 250.318 1.00 39.28  ? 422  GLU A CB    1 
ATOM   3304  C CG    . GLU A 1 422  ? 241.949 334.571 249.424 1.00 39.28  ? 422  GLU A CG    1 
ATOM   3305  C CD    . GLU A 1 422  ? 243.246 333.896 249.821 1.00 39.28  ? 422  GLU A CD    1 
ATOM   3306  O OE1   . GLU A 1 422  ? 243.236 332.666 250.036 1.00 39.28  ? 422  GLU A OE1   1 
ATOM   3307  O OE2   . GLU A 1 422  ? 244.276 334.596 249.916 1.00 39.28  ? 422  GLU A OE2   1 
ATOM   3308  N N     . ILE A 1 423  ? 237.766 334.328 250.989 1.00 37.06  ? 423  ILE A N     1 
ATOM   3309  C CA    . ILE A 1 423  ? 236.599 334.153 251.853 1.00 37.06  ? 423  ILE A CA    1 
ATOM   3310  C C     . ILE A 1 423  ? 235.407 333.584 251.101 1.00 37.06  ? 423  ILE A C     1 
ATOM   3311  O O     . ILE A 1 423  ? 234.515 332.992 251.723 1.00 37.06  ? 423  ILE A O     1 
ATOM   3312  C CB    . ILE A 1 423  ? 236.252 335.500 252.517 1.00 37.06  ? 423  ILE A CB    1 
ATOM   3313  C CG1   . ILE A 1 423  ? 237.467 336.045 253.264 1.00 37.06  ? 423  ILE A CG1   1 
ATOM   3314  C CG2   . ILE A 1 423  ? 235.088 335.362 253.488 1.00 37.06  ? 423  ILE A CG2   1 
ATOM   3315  C CD1   . ILE A 1 423  ? 237.969 335.130 254.360 1.00 37.06  ? 423  ILE A CD1   1 
ATOM   3316  N N     . ASP A 1 424  ? 235.384 333.703 249.775 1.00 36.26  ? 424  ASP A N     1 
ATOM   3317  C CA    . ASP A 1 424  ? 234.264 333.249 248.953 1.00 36.26  ? 424  ASP A CA    1 
ATOM   3318  C C     . ASP A 1 424  ? 234.826 332.308 247.892 1.00 36.26  ? 424  ASP A C     1 
ATOM   3319  O O     . ASP A 1 424  ? 235.059 332.706 246.744 1.00 36.26  ? 424  ASP A O     1 
ATOM   3320  C CB    . ASP A 1 424  ? 233.533 334.447 248.338 1.00 36.26  ? 424  ASP A CB    1 
ATOM   3321  C CG    . ASP A 1 424  ? 232.380 334.055 247.408 1.00 36.26  ? 424  ASP A CG    1 
ATOM   3322  O OD1   . ASP A 1 424  ? 232.411 332.998 246.746 1.00 36.26  ? 424  ASP A OD1   1 
ATOM   3323  O OD2   . ASP A 1 424  ? 231.407 334.835 247.353 1.00 36.26  ? 424  ASP A OD2   1 
ATOM   3324  N N     . PRO A 1 425  ? 235.094 331.051 248.258 1.00 27.60  ? 425  PRO A N     1 
ATOM   3325  C CA    . PRO A 1 425  ? 235.531 330.075 247.248 1.00 27.60  ? 425  PRO A CA    1 
ATOM   3326  C C     . PRO A 1 425  ? 234.414 329.612 246.330 1.00 27.60  ? 425  PRO A C     1 
ATOM   3327  O O     . PRO A 1 425  ? 234.699 329.016 245.284 1.00 27.60  ? 425  PRO A O     1 
ATOM   3328  C CB    . PRO A 1 425  ? 236.076 328.915 248.092 1.00 27.60  ? 425  PRO A CB    1 
ATOM   3329  C CG    . PRO A 1 425  ? 235.346 329.022 249.384 1.00 27.60  ? 425  PRO A CG    1 
ATOM   3330  C CD    . PRO A 1 425  ? 235.113 330.487 249.619 1.00 27.60  ? 425  PRO A CD    1 
ATOM   3331  N N     . LEU A 1 426  ? 233.154 329.865 246.683 1.00 32.15  ? 426  LEU A N     1 
ATOM   3332  C CA    . LEU A 1 426  ? 232.019 329.407 245.892 1.00 32.15  ? 426  LEU A CA    1 
ATOM   3333  C C     . LEU A 1 426  ? 231.686 330.336 244.731 1.00 32.15  ? 426  LEU A C     1 
ATOM   3334  O O     . LEU A 1 426  ? 230.749 330.043 243.980 1.00 32.15  ? 426  LEU A O     1 
ATOM   3335  C CB    . LEU A 1 426  ? 230.787 329.242 246.787 1.00 32.15  ? 426  LEU A CB    1 
ATOM   3336  C CG    . LEU A 1 426  ? 230.951 328.328 248.003 1.00 32.15  ? 426  LEU A CG    1 
ATOM   3337  C CD1   . LEU A 1 426  ? 229.707 328.370 248.878 1.00 32.15  ? 426  LEU A CD1   1 
ATOM   3338  C CD2   . LEU A 1 426  ? 231.256 326.904 247.565 1.00 32.15  ? 426  LEU A CD2   1 
ATOM   3339  N N     . ASN A 1 427  ? 232.419 331.440 244.576 1.00 38.41  ? 427  ASN A N     1 
ATOM   3340  C CA    . ASN A 1 427  ? 232.216 332.386 243.477 1.00 38.41  ? 427  ASN A CA    1 
ATOM   3341  C C     . ASN A 1 427  ? 230.801 332.964 243.498 1.00 38.41  ? 427  ASN A C     1 
ATOM   3342  O O     . ASN A 1 427  ? 230.091 332.976 242.491 1.00 38.41  ? 427  ASN A O     1 
ATOM   3343  C CB    . ASN A 1 427  ? 232.526 331.741 242.121 1.00 38.41  ? 427  ASN A CB    1 
ATOM   3344  C CG    . ASN A 1 427  ? 233.933 331.171 242.047 1.00 38.41  ? 427  ASN A CG    1 
ATOM   3345  O OD1   . ASN A 1 427  ? 234.774 331.459 242.899 1.00 38.41  ? 427  ASN A OD1   1 
ATOM   3346  N ND2   . ASN A 1 427  ? 234.188 330.340 241.042 1.00 38.41  ? 427  ASN A ND2   1 
ATOM   3347  N N     . ARG A 1 428  ? 230.392 333.448 244.669 1.00 38.43  ? 428  ARG A N     1 
ATOM   3348  C CA    . ARG A 1 428  ? 229.106 334.112 244.829 1.00 38.43  ? 428  ARG A CA    1 
ATOM   3349  C C     . ARG A 1 428  ? 229.169 335.599 244.505 1.00 38.43  ? 428  ARG A C     1 
ATOM   3350  O O     . ARG A 1 428  ? 228.135 336.273 244.553 1.00 38.43  ? 428  ARG A O     1 
ATOM   3351  C CB    . ARG A 1 428  ? 228.584 333.917 246.256 1.00 38.43  ? 428  ARG A CB    1 
ATOM   3352  C CG    . ARG A 1 428  ? 228.220 332.482 246.597 1.00 38.43  ? 428  ARG A CG    1 
ATOM   3353  C CD    . ARG A 1 428  ? 227.220 332.425 247.743 1.00 38.43  ? 428  ARG A CD    1 
ATOM   3354  N NE    . ARG A 1 428  ? 225.927 332.993 247.379 1.00 38.43  ? 428  ARG A NE    1 
ATOM   3355  C CZ    . ARG A 1 428  ? 225.034 332.394 246.603 1.00 38.43  ? 428  ARG A CZ    1 
ATOM   3356  N NH1   . ARG A 1 428  ? 225.254 331.192 246.094 1.00 38.43  ? 428  ARG A NH1   1 
ATOM   3357  N NH2   . ARG A 1 428  ? 223.889 333.015 246.333 1.00 38.43  ? 428  ARG A NH2   1 
ATOM   3358  N N     . ARG A 1 429  ? 230.354 336.122 244.180 1.00 42.12  ? 429  ARG A N     1 
ATOM   3359  C CA    . ARG A 1 429  ? 230.476 337.535 243.839 1.00 42.12  ? 429  ARG A CA    1 
ATOM   3360  C C     . ARG A 1 429  ? 229.793 337.858 242.517 1.00 42.12  ? 429  ARG A C     1 
ATOM   3361  O O     . ARG A 1 429  ? 229.333 338.988 242.318 1.00 42.12  ? 429  ARG A O     1 
ATOM   3362  C CB    . ARG A 1 429  ? 231.951 337.934 243.779 1.00 42.12  ? 429  ARG A CB    1 
ATOM   3363  C CG    . ARG A 1 429  ? 232.813 337.301 244.858 1.00 42.12  ? 429  ARG A CG    1 
ATOM   3364  C CD    . ARG A 1 429  ? 234.186 337.954 244.922 1.00 42.12  ? 429  ARG A CD    1 
ATOM   3365  N NE    . ARG A 1 429  ? 234.981 337.690 243.729 1.00 42.12  ? 429  ARG A NE    1 
ATOM   3366  C CZ    . ARG A 1 429  ? 235.585 336.538 243.468 1.00 42.12  ? 429  ARG A CZ    1 
ATOM   3367  N NH1   . ARG A 1 429  ? 235.510 335.513 244.302 1.00 42.12  ? 429  ARG A NH1   1 
ATOM   3368  N NH2   . ARG A 1 429  ? 236.285 336.412 242.344 1.00 42.12  ? 429  ARG A NH2   1 
ATOM   3369  N N     . PHE A 1 430  ? 229.717 336.886 241.605 1.00 46.51  ? 430  PHE A N     1 
ATOM   3370  C CA    . PHE A 1 430  ? 229.130 337.085 240.286 1.00 46.51  ? 430  PHE A CA    1 
ATOM   3371  C C     . PHE A 1 430  ? 227.651 336.720 240.238 1.00 46.51  ? 430  PHE A C     1 
ATOM   3372  O O     . PHE A 1 430  ? 227.146 336.332 239.175 1.00 46.51  ? 430  PHE A O     1 
ATOM   3373  C CB    . PHE A 1 430  ? 229.910 336.285 239.241 1.00 46.51  ? 430  PHE A CB    1 
ATOM   3374  C CG    . PHE A 1 430  ? 231.397 336.298 239.454 1.00 46.51  ? 430  PHE A CG    1 
ATOM   3375  C CD1   . PHE A 1 430  ? 232.105 337.488 239.421 1.00 46.51  ? 430  PHE A CD1   1 
ATOM   3376  C CD2   . PHE A 1 430  ? 232.087 335.120 239.686 1.00 46.51  ? 430  PHE A CD2   1 
ATOM   3377  C CE1   . PHE A 1 430  ? 233.473 337.504 239.617 1.00 46.51  ? 430  PHE A CE1   1 
ATOM   3378  C CE2   . PHE A 1 430  ? 233.456 335.129 239.882 1.00 46.51  ? 430  PHE A CE2   1 
ATOM   3379  C CZ    . PHE A 1 430  ? 234.149 336.322 239.847 1.00 46.51  ? 430  PHE A CZ    1 
ATOM   3380  N N     . SER A 1 431  ? 226.942 336.832 241.363 1.00 53.25  ? 431  SER A N     1 
ATOM   3381  C CA    . SER A 1 431  ? 225.516 336.525 241.382 1.00 53.25  ? 431  SER A CA    1 
ATOM   3382  C C     . SER A 1 431  ? 224.692 337.543 240.605 1.00 53.25  ? 431  SER A C     1 
ATOM   3383  O O     . SER A 1 431  ? 223.549 337.248 240.241 1.00 53.25  ? 431  SER A O     1 
ATOM   3384  C CB    . SER A 1 431  ? 225.015 336.443 242.825 1.00 53.25  ? 431  SER A CB    1 
ATOM   3385  O OG    . SER A 1 431  ? 225.275 337.648 243.524 1.00 53.25  ? 431  SER A OG    1 
ATOM   3386  N N     . THR A 1 432  ? 225.240 338.728 240.344 1.00 61.34  ? 432  THR A N     1 
ATOM   3387  C CA    . THR A 1 432  ? 224.536 339.771 239.611 1.00 61.34  ? 432  THR A CA    1 
ATOM   3388  C C     . THR A 1 432  ? 224.803 339.729 238.112 1.00 61.34  ? 432  THR A C     1 
ATOM   3389  O O     . THR A 1 432  ? 224.291 340.586 237.384 1.00 61.34  ? 432  THR A O     1 
ATOM   3390  C CB    . THR A 1 432  ? 224.916 341.151 240.159 1.00 61.34  ? 432  THR A CB    1 
ATOM   3391  O OG1   . THR A 1 432  ? 226.306 341.399 239.915 1.00 61.34  ? 432  THR A OG1   1 
ATOM   3392  C CG2   . THR A 1 432  ? 224.648 341.223 241.655 1.00 61.34  ? 432  THR A CG2   1 
ATOM   3393  N N     . VAL A 1 433  ? 225.587 338.769 237.639 1.00 68.25  ? 433  VAL A N     1 
ATOM   3394  C CA    . VAL A 1 433  ? 225.867 338.669 236.201 1.00 68.25  ? 433  VAL A CA    1 
ATOM   3395  C C     . VAL A 1 433  ? 224.597 338.242 235.473 1.00 68.25  ? 433  VAL A C     1 
ATOM   3396  O O     . VAL A 1 433  ? 223.979 337.230 235.851 1.00 68.25  ? 433  VAL A O     1 
ATOM   3397  C CB    . VAL A 1 433  ? 227.006 337.680 235.949 1.00 68.25  ? 433  VAL A CB    1 
ATOM   3398  C CG1   . VAL A 1 433  ? 227.163 337.420 234.458 1.00 68.25  ? 433  VAL A CG1   1 
ATOM   3399  C CG2   . VAL A 1 433  ? 228.304 338.208 236.540 1.00 68.25  ? 433  VAL A CG2   1 
ATOM   3400  N N     . PRO A 1 434  ? 224.162 338.973 234.447 1.00 84.57  ? 434  PRO A N     1 
ATOM   3401  C CA    . PRO A 1 434  ? 222.934 338.593 233.737 1.00 84.57  ? 434  PRO A CA    1 
ATOM   3402  C C     . PRO A 1 434  ? 223.070 337.236 233.062 1.00 84.57  ? 434  PRO A C     1 
ATOM   3403  O O     . PRO A 1 434  ? 224.142 336.861 232.583 1.00 84.57  ? 434  PRO A O     1 
ATOM   3404  C CB    . PRO A 1 434  ? 222.754 339.717 232.709 1.00 84.57  ? 434  PRO A CB    1 
ATOM   3405  C CG    . PRO A 1 434  ? 223.571 340.858 233.229 1.00 84.57  ? 434  PRO A CG    1 
ATOM   3406  C CD    . PRO A 1 434  ? 224.727 340.237 233.947 1.00 84.57  ? 434  PRO A CD    1 
ATOM   3407  N N     . LYS A 1 435  ? 221.959 336.498 233.028 1.00 92.31  ? 435  LYS A N     1 
ATOM   3408  C CA    . LYS A 1 435  ? 221.901 335.200 232.364 1.00 92.31  ? 435  LYS A CA    1 
ATOM   3409  C C     . LYS A 1 435  ? 221.591 335.398 230.885 1.00 92.31  ? 435  LYS A C     1 
ATOM   3410  O O     . LYS A 1 435  ? 220.568 336.007 230.551 1.00 92.31  ? 435  LYS A O     1 
ATOM   3411  C CB    . LYS A 1 435  ? 220.843 334.312 233.016 1.00 92.31  ? 435  LYS A CB    1 
ATOM   3412  C CG    . LYS A 1 435  ? 220.810 332.860 232.538 1.00 92.31  ? 435  LYS A CG    1 
ATOM   3413  C CD    . LYS A 1 435  ? 219.895 332.661 231.338 1.00 92.31  ? 435  LYS A CD    1 
ATOM   3414  C CE    . LYS A 1 435  ? 218.434 332.810 231.731 1.00 92.31  ? 435  LYS A CE    1 
ATOM   3415  N NZ    . LYS A 1 435  ? 217.521 332.547 230.585 1.00 92.31  ? 435  LYS A NZ    1 
ATOM   3416  N N     . PRO A 1 436  ? 222.445 334.910 229.978 1.00 103.84 ? 436  PRO A N     1 
ATOM   3417  C CA    . PRO A 1 436  ? 222.235 335.174 228.546 1.00 103.84 ? 436  PRO A CA    1 
ATOM   3418  C C     . PRO A 1 436  ? 220.950 334.571 227.995 1.00 103.84 ? 436  PRO A C     1 
ATOM   3419  O O     . PRO A 1 436  ? 220.106 335.297 227.459 1.00 103.84 ? 436  PRO A O     1 
ATOM   3420  C CB    . PRO A 1 436  ? 223.472 334.547 227.888 1.00 103.84 ? 436  PRO A CB    1 
ATOM   3421  C CG    . PRO A 1 436  ? 223.968 333.540 228.874 1.00 103.84 ? 436  PRO A CG    1 
ATOM   3422  C CD    . PRO A 1 436  ? 223.643 334.092 230.228 1.00 103.84 ? 436  PRO A CD    1 
ATOM   3423  N N     . ASP A 1 437  ? 220.784 333.257 228.133 1.00 93.84  ? 437  ASP A N     1 
ATOM   3424  C CA    . ASP A 1 437  ? 219.626 332.552 227.596 1.00 93.84  ? 437  ASP A CA    1 
ATOM   3425  C C     . ASP A 1 437  ? 219.674 331.111 228.090 1.00 93.84  ? 437  ASP A C     1 
ATOM   3426  O O     . ASP A 1 437  ? 220.614 330.697 228.774 1.00 93.84  ? 437  ASP A O     1 
ATOM   3427  C CB    . ASP A 1 437  ? 219.584 332.586 226.067 1.00 93.84  ? 437  ASP A CB    1 
ATOM   3428  N N     . VAL A 1 438  ? 218.641 330.352 227.730 1.00 70.77  ? 438  VAL A N     1 
ATOM   3429  C CA    . VAL A 1 438  ? 218.548 328.935 228.056 1.00 70.77  ? 438  VAL A CA    1 
ATOM   3430  C C     . VAL A 1 438  ? 217.655 328.260 227.022 1.00 70.77  ? 438  VAL A C     1 
ATOM   3431  O O     . VAL A 1 438  ? 216.667 328.843 226.562 1.00 70.77  ? 438  VAL A O     1 
ATOM   3432  C CB    . VAL A 1 438  ? 218.012 328.714 229.488 1.00 70.77  ? 438  VAL A CB    1 
ATOM   3433  C CG1   . VAL A 1 438  ? 216.650 329.367 229.660 1.00 70.77  ? 438  VAL A CG1   1 
ATOM   3434  C CG2   . VAL A 1 438  ? 217.944 327.231 229.815 1.00 70.77  ? 438  VAL A CG2   1 
ATOM   3435  N N     . VAL A 1 439  ? 218.014 327.036 226.644 1.00 55.03  ? 439  VAL A N     1 
ATOM   3436  C CA    . VAL A 1 439  ? 217.240 326.230 225.707 1.00 55.03  ? 439  VAL A CA    1 
ATOM   3437  C C     . VAL A 1 439  ? 216.661 325.045 226.466 1.00 55.03  ? 439  VAL A C     1 
ATOM   3438  O O     . VAL A 1 439  ? 217.397 324.311 227.137 1.00 55.03  ? 439  VAL A O     1 
ATOM   3439  C CB    . VAL A 1 439  ? 218.099 325.760 224.521 1.00 55.03  ? 439  VAL A CB    1 
ATOM   3440  C CG1   . VAL A 1 439  ? 217.225 325.104 223.462 1.00 55.03  ? 439  VAL A CG1   1 
ATOM   3441  C CG2   . VAL A 1 439  ? 218.875 326.928 223.932 1.00 55.03  ? 439  VAL A CG2   1 
ATOM   3442  N N     . VAL A 1 440  ? 215.348 324.860 226.359 1.00 46.59  ? 440  VAL A N     1 
ATOM   3443  C CA    . VAL A 1 440  ? 214.642 323.788 227.052 1.00 46.59  ? 440  VAL A CA    1 
ATOM   3444  C C     . VAL A 1 440  ? 214.303 322.697 226.045 1.00 46.59  ? 440  VAL A C     1 
ATOM   3445  O O     . VAL A 1 440  ? 213.963 322.987 224.891 1.00 46.59  ? 440  VAL A O     1 
ATOM   3446  C CB    . VAL A 1 440  ? 213.381 324.317 227.760 1.00 46.59  ? 440  VAL A CB    1 
ATOM   3447  C CG1   . VAL A 1 440  ? 212.389 324.890 226.756 1.00 46.59  ? 440  VAL A CG1   1 
ATOM   3448  C CG2   . VAL A 1 440  ? 212.736 323.223 228.598 1.00 46.59  ? 440  VAL A CG2   1 
ATOM   3449  N N     . GLN A 1 441  ? 214.422 321.443 226.472 1.00 39.94  ? 441  GLN A N     1 
ATOM   3450  C CA    . GLN A 1 441  ? 214.165 320.290 225.620 1.00 39.94  ? 441  GLN A CA    1 
ATOM   3451  C C     . GLN A 1 441  ? 212.869 319.616 226.050 1.00 39.94  ? 441  GLN A C     1 
ATOM   3452  O O     . GLN A 1 441  ? 212.653 319.381 227.244 1.00 39.94  ? 441  GLN A O     1 
ATOM   3453  C CB    . GLN A 1 441  ? 215.328 319.300 225.688 1.00 39.94  ? 441  GLN A CB    1 
ATOM   3454  C CG    . GLN A 1 441  ? 216.695 319.947 225.527 1.00 39.94  ? 441  GLN A CG    1 
ATOM   3455  C CD    . GLN A 1 441  ? 217.829 319.032 225.942 1.00 39.94  ? 441  GLN A CD    1 
ATOM   3456  O OE1   . GLN A 1 441  ? 218.716 318.722 225.147 1.00 39.94  ? 441  GLN A OE1   1 
ATOM   3457  N NE2   . GLN A 1 441  ? 217.806 318.593 227.196 1.00 39.94  ? 441  GLN A NE2   1 
ATOM   3458  N N     . VAL A 1 442  ? 212.012 319.310 225.080 1.00 32.29  ? 442  VAL A N     1 
ATOM   3459  C CA    . VAL A 1 442  ? 210.723 318.676 225.330 1.00 32.29  ? 442  VAL A CA    1 
ATOM   3460  C C     . VAL A 1 442  ? 210.668 317.373 224.545 1.00 32.29  ? 442  VAL A C     1 
ATOM   3461  O O     . VAL A 1 442  ? 210.947 317.355 223.340 1.00 32.29  ? 442  VAL A O     1 
ATOM   3462  C CB    . VAL A 1 442  ? 209.551 319.600 224.950 1.00 32.29  ? 442  VAL A CB    1 
ATOM   3463  C CG1   . VAL A 1 442  ? 208.326 318.788 224.548 1.00 32.29  ? 442  VAL A CG1   1 
ATOM   3464  C CG2   . VAL A 1 442  ? 209.221 320.538 226.101 1.00 32.29  ? 442  VAL A CG2   1 
ATOM   3465  N N     . SER A 1 443  ? 210.318 316.286 225.229 1.00 31.61  ? 443  SER A N     1 
ATOM   3466  C CA    . SER A 1 443  ? 210.174 314.972 224.619 1.00 31.61  ? 443  SER A CA    1 
ATOM   3467  C C     . SER A 1 443  ? 208.722 314.531 224.732 1.00 31.61  ? 443  SER A C     1 
ATOM   3468  O O     . SER A 1 443  ? 208.117 314.642 225.803 1.00 31.61  ? 443  SER A O     1 
ATOM   3469  C CB    . SER A 1 443  ? 211.096 313.948 225.285 1.00 31.61  ? 443  SER A CB    1 
ATOM   3470  O OG    . SER A 1 443  ? 211.104 312.726 224.567 1.00 31.61  ? 443  SER A OG    1 
ATOM   3471  N N     . ILE A 1 444  ? 208.168 314.035 223.629 1.00 35.69  ? 444  ILE A N     1 
ATOM   3472  C CA    . ILE A 1 444  ? 206.769 313.632 223.551 1.00 35.69  ? 444  ILE A CA    1 
ATOM   3473  C C     . ILE A 1 444  ? 206.721 312.130 223.310 1.00 35.69  ? 444  ILE A C     1 
ATOM   3474  O O     . ILE A 1 444  ? 207.394 311.618 222.407 1.00 35.69  ? 444  ILE A O     1 
ATOM   3475  C CB    . ILE A 1 444  ? 206.022 314.393 222.445 1.00 35.69  ? 444  ILE A CB    1 
ATOM   3476  C CG1   . ILE A 1 444  ? 206.152 315.903 222.658 1.00 35.69  ? 444  ILE A CG1   1 
ATOM   3477  C CG2   . ILE A 1 444  ? 204.558 313.983 222.409 1.00 35.69  ? 444  ILE A CG2   1 
ATOM   3478  C CD1   . ILE A 1 444  ? 206.593 316.657 221.423 1.00 35.69  ? 444  ILE A CD1   1 
ATOM   3479  N N     . LEU A 1 445  ? 205.933 311.425 224.117 1.00 40.49  ? 445  LEU A N     1 
ATOM   3480  C CA    . LEU A 1 445  ? 205.759 309.988 223.986 1.00 40.49  ? 445  LEU A CA    1 
ATOM   3481  C C     . LEU A 1 445  ? 204.284 309.639 223.843 1.00 40.49  ? 445  LEU A C     1 
ATOM   3482  O O     . LEU A 1 445  ? 203.403 310.402 224.252 1.00 40.49  ? 445  LEU A O     1 
ATOM   3483  C CB    . LEU A 1 445  ? 206.348 309.240 225.186 1.00 40.49  ? 445  LEU A CB    1 
ATOM   3484  C CG    . LEU A 1 445  ? 207.619 309.798 225.824 1.00 40.49  ? 445  LEU A CG    1 
ATOM   3485  C CD1   . LEU A 1 445  ? 207.756 309.287 227.249 1.00 40.49  ? 445  LEU A CD1   1 
ATOM   3486  C CD2   . LEU A 1 445  ? 208.840 309.430 224.997 1.00 40.49  ? 445  LEU A CD2   1 
ATOM   3487  N N     . ALA A 1 446  ? 204.025 308.474 223.258 1.00 50.39  ? 446  ALA A N     1 
ATOM   3488  C CA    . ALA A 1 446  ? 202.674 307.963 223.074 1.00 50.39  ? 446  ALA A CA    1 
ATOM   3489  C C     . ALA A 1 446  ? 202.428 306.825 224.054 1.00 50.39  ? 446  ALA A C     1 
ATOM   3490  O O     . ALA A 1 446  ? 203.252 305.912 224.174 1.00 50.39  ? 446  ALA A O     1 
ATOM   3491  C CB    . ALA A 1 446  ? 202.462 307.483 221.638 1.00 50.39  ? 446  ALA A CB    1 
ATOM   3492  N N     . GLU A 1 447  ? 201.295 306.887 224.759 1.00 57.11  ? 447  GLU A N     1 
ATOM   3493  C CA    . GLU A 1 447  ? 200.988 305.865 225.756 1.00 57.11  ? 447  GLU A CA    1 
ATOM   3494  C C     . GLU A 1 447  ? 200.790 304.498 225.112 1.00 57.11  ? 447  GLU A C     1 
ATOM   3495  O O     . GLU A 1 447  ? 201.245 303.481 225.647 1.00 57.11  ? 447  GLU A O     1 
ATOM   3496  C CB    . GLU A 1 447  ? 199.748 306.267 226.554 1.00 57.11  ? 447  GLU A CB    1 
ATOM   3497  C CG    . GLU A 1 447  ? 199.840 305.952 228.038 1.00 57.11  ? 447  GLU A CG    1 
ATOM   3498  C CD    . GLU A 1 447  ? 199.067 306.937 228.892 1.00 57.11  ? 447  GLU A CD    1 
ATOM   3499  O OE1   . GLU A 1 447  ? 199.480 307.178 230.046 1.00 57.11  ? 447  GLU A OE1   1 
ATOM   3500  O OE2   . GLU A 1 447  ? 198.046 307.469 228.411 1.00 57.11  ? 447  GLU A OE2   1 
ATOM   3501  N N     . THR A 1 448  ? 200.115 304.453 223.964 1.00 62.75  ? 448  THR A N     1 
ATOM   3502  C CA    . THR A 1 448  ? 199.805 303.198 223.295 1.00 62.75  ? 448  THR A CA    1 
ATOM   3503  C C     . THR A 1 448  ? 200.215 303.296 221.831 1.00 62.75  ? 448  THR A C     1 
ATOM   3504  O O     . THR A 1 448  ? 200.671 304.342 221.357 1.00 62.75  ? 448  THR A O     1 
ATOM   3505  C CB    . THR A 1 448  ? 198.317 302.849 223.427 1.00 62.75  ? 448  THR A CB    1 
ATOM   3506  O OG1   . THR A 1 448  ? 197.525 304.006 223.131 1.00 62.75  ? 448  THR A OG1   1 
ATOM   3507  C CG2   . THR A 1 448  ? 198.004 302.371 224.837 1.00 62.75  ? 448  THR A CG2   1 
ATOM   3508  N N     . GLU A 1 449  ? 200.050 302.184 221.110 1.00 66.59  ? 449  GLU A N     1 
ATOM   3509  C CA    . GLU A 1 449  ? 200.432 302.142 219.702 1.00 66.59  ? 449  GLU A CA    1 
ATOM   3510  C C     . GLU A 1 449  ? 199.515 303.008 218.848 1.00 66.59  ? 449  GLU A C     1 
ATOM   3511  O O     . GLU A 1 449  ? 199.959 303.607 217.861 1.00 66.59  ? 449  GLU A O     1 
ATOM   3512  C CB    . GLU A 1 449  ? 200.425 300.696 219.204 1.00 66.59  ? 449  GLU A CB    1 
ATOM   3513  C CG    . GLU A 1 449  ? 200.882 300.515 217.761 1.00 66.59  ? 449  GLU A CG    1 
ATOM   3514  C CD    . GLU A 1 449  ? 202.321 300.941 217.539 1.00 66.59  ? 449  GLU A CD    1 
ATOM   3515  O OE1   . GLU A 1 449  ? 202.565 302.150 217.341 1.00 66.59  ? 449  GLU A OE1   1 
ATOM   3516  O OE2   . GLU A 1 449  ? 203.210 300.064 217.561 1.00 66.59  ? 449  GLU A OE2   1 
ATOM   3517  N N     . GLU A 1 450  ? 198.229 303.079 219.205 1.00 67.50  ? 450  GLU A N     1 
ATOM   3518  C CA    . GLU A 1 450  ? 197.285 303.869 218.420 1.00 67.50  ? 450  GLU A CA    1 
ATOM   3519  C C     . GLU A 1 450  ? 197.648 305.349 218.441 1.00 67.50  ? 450  GLU A C     1 
ATOM   3520  O O     . GLU A 1 450  ? 197.544 306.035 217.417 1.00 67.50  ? 450  GLU A O     1 
ATOM   3521  C CB    . GLU A 1 450  ? 195.861 303.654 218.935 1.00 67.50  ? 450  GLU A CB    1 
ATOM   3522  C CG    . GLU A 1 450  ? 195.714 303.767 220.444 1.00 67.50  ? 450  GLU A CG    1 
ATOM   3523  C CD    . GLU A 1 450  ? 195.617 302.415 221.123 1.00 67.50  ? 450  GLU A CD    1 
ATOM   3524  O OE1   . GLU A 1 450  ? 196.396 301.509 220.760 1.00 67.50  ? 450  GLU A OE1   1 
ATOM   3525  O OE2   . GLU A 1 450  ? 194.762 302.259 222.020 1.00 67.50  ? 450  GLU A OE2   1 
ATOM   3526  N N     . ILE A 1 451  ? 198.073 305.861 219.599 1.00 61.51  ? 451  ILE A N     1 
ATOM   3527  C CA    . ILE A 1 451  ? 198.469 307.263 219.693 1.00 61.51  ? 451  ILE A CA    1 
ATOM   3528  C C     . ILE A 1 451  ? 199.680 307.537 218.811 1.00 61.51  ? 451  ILE A C     1 
ATOM   3529  O O     . ILE A 1 451  ? 199.740 308.556 218.110 1.00 61.51  ? 451  ILE A O     1 
ATOM   3530  C CB    . ILE A 1 451  ? 198.738 307.646 221.160 1.00 61.51  ? 451  ILE A CB    1 
ATOM   3531  C CG1   . ILE A 1 451  ? 197.525 307.314 222.033 1.00 61.51  ? 451  ILE A CG1   1 
ATOM   3532  C CG2   . ILE A 1 451  ? 199.090 309.120 221.271 1.00 61.51  ? 451  ILE A CG2   1 
ATOM   3533  C CD1   . ILE A 1 451  ? 196.225 307.901 221.525 1.00 61.51  ? 451  ILE A CD1   1 
ATOM   3534  N N     . LYS A 1 452  ? 200.667 306.638 218.836 1.00 57.48  ? 452  LYS A N     1 
ATOM   3535  C CA    . LYS A 1 452  ? 201.849 306.814 217.998 1.00 57.48  ? 452  LYS A CA    1 
ATOM   3536  C C     . LYS A 1 452  ? 201.487 306.773 216.519 1.00 57.48  ? 452  LYS A C     1 
ATOM   3537  O O     . LYS A 1 452  ? 202.007 307.562 215.724 1.00 57.48  ? 452  LYS A O     1 
ATOM   3538  C CB    . LYS A 1 452  ? 202.893 305.746 218.326 1.00 57.48  ? 452  LYS A CB    1 
ATOM   3539  C CG    . LYS A 1 452  ? 204.251 305.994 217.688 1.00 57.48  ? 452  LYS A CG    1 
ATOM   3540  C CD    . LYS A 1 452  ? 205.234 304.883 218.020 1.00 57.48  ? 452  LYS A CD    1 
ATOM   3541  C CE    . LYS A 1 452  ? 205.309 303.858 216.900 1.00 57.48  ? 452  LYS A CE    1 
ATOM   3542  N NZ    . LYS A 1 452  ? 206.140 304.338 215.762 1.00 57.48  ? 452  LYS A NZ    1 
ATOM   3543  N N     . THR A 1 453  ? 200.595 305.856 216.132 1.00 59.55  ? 453  THR A N     1 
ATOM   3544  C CA    . THR A 1 453  ? 200.163 305.785 214.740 1.00 59.55  ? 453  THR A CA    1 
ATOM   3545  C C     . THR A 1 453  ? 199.436 307.058 214.322 1.00 59.55  ? 453  THR A C     1 
ATOM   3546  O O     . THR A 1 453  ? 199.652 307.573 213.217 1.00 59.55  ? 453  THR A O     1 
ATOM   3547  C CB    . THR A 1 453  ? 199.269 304.563 214.528 1.00 59.55  ? 453  THR A CB    1 
ATOM   3548  O OG1   . THR A 1 453  ? 199.951 303.386 214.980 1.00 59.55  ? 453  THR A OG1   1 
ATOM   3549  C CG2   . THR A 1 453  ? 198.920 304.405 213.055 1.00 59.55  ? 453  THR A CG2   1 
ATOM   3550  N N     . ILE A 1 454  ? 198.569 307.580 215.193 1.00 55.03  ? 454  ILE A N     1 
ATOM   3551  C CA    . ILE A 1 454  ? 197.846 308.811 214.885 1.00 55.03  ? 454  ILE A CA    1 
ATOM   3552  C C     . ILE A 1 454  ? 198.817 309.974 214.725 1.00 55.03  ? 454  ILE A C     1 
ATOM   3553  O O     . ILE A 1 454  ? 198.697 310.779 213.792 1.00 55.03  ? 454  ILE A O     1 
ATOM   3554  C CB    . ILE A 1 454  ? 196.790 309.096 215.970 1.00 55.03  ? 454  ILE A CB    1 
ATOM   3555  C CG1   . ILE A 1 454  ? 195.605 308.140 215.824 1.00 55.03  ? 454  ILE A CG1   1 
ATOM   3556  C CG2   . ILE A 1 454  ? 196.321 310.542 215.901 1.00 55.03  ? 454  ILE A CG2   1 
ATOM   3557  C CD1   . ILE A 1 454  ? 194.804 307.963 217.095 1.00 55.03  ? 454  ILE A CD1   1 
ATOM   3558  N N     . LEU A 1 455  ? 199.796 310.080 215.627 1.00 58.41  ? 455  LEU A N     1 
ATOM   3559  C CA    . LEU A 1 455  ? 200.776 311.158 215.528 1.00 58.41  ? 455  LEU A CA    1 
ATOM   3560  C C     . LEU A 1 455  ? 201.615 311.029 214.263 1.00 58.41  ? 455  LEU A C     1 
ATOM   3561  O O     . LEU A 1 455  ? 201.930 312.034 213.614 1.00 58.41  ? 455  LEU A O     1 
ATOM   3562  C CB    . LEU A 1 455  ? 201.668 311.176 216.769 1.00 58.41  ? 455  LEU A CB    1 
ATOM   3563  C CG    . LEU A 1 455  ? 201.279 312.193 217.845 1.00 58.41  ? 455  LEU A CG    1 
ATOM   3564  C CD1   . LEU A 1 455  ? 200.025 311.746 218.579 1.00 58.41  ? 455  LEU A CD1   1 
ATOM   3565  C CD2   . LEU A 1 455  ? 202.422 312.423 218.820 1.00 58.41  ? 455  LEU A CD2   1 
ATOM   3566  N N     . LYS A 1 456  ? 201.991 309.801 213.898 1.00 60.22  ? 456  LYS A N     1 
ATOM   3567  C CA    . LYS A 1 456  ? 202.740 309.590 212.663 1.00 60.22  ? 456  LYS A CA    1 
ATOM   3568  C C     . LYS A 1 456  ? 201.917 309.994 211.447 1.00 60.22  ? 456  LYS A C     1 
ATOM   3569  O O     . LYS A 1 456  ? 202.445 310.584 210.497 1.00 60.22  ? 456  LYS A O     1 
ATOM   3570  C CB    . LYS A 1 456  ? 203.179 308.128 212.560 1.00 60.22  ? 456  LYS A CB    1 
ATOM   3571  C CG    . LYS A 1 456  ? 203.925 307.780 211.280 1.00 60.22  ? 456  LYS A CG    1 
ATOM   3572  C CD    . LYS A 1 456  ? 203.048 306.993 210.318 1.00 60.22  ? 456  LYS A CD    1 
ATOM   3573  C CE    . LYS A 1 456  ? 202.963 305.529 210.719 1.00 60.22  ? 456  LYS A CE    1 
ATOM   3574  N NZ    . LYS A 1 456  ? 202.232 304.718 209.707 1.00 60.22  ? 456  LYS A NZ    1 
ATOM   3575  N N     . ASP A 1 457  ? 200.619 309.679 211.457 1.00 67.24  ? 457  ASP A N     1 
ATOM   3576  C CA    . ASP A 1 457  ? 199.747 310.096 210.364 1.00 67.24  ? 457  ASP A CA    1 
ATOM   3577  C C     . ASP A 1 457  ? 199.657 311.614 210.271 1.00 67.24  ? 457  ASP A C     1 
ATOM   3578  O O     . ASP A 1 457  ? 199.493 312.161 209.174 1.00 67.24  ? 457  ASP A O     1 
ATOM   3579  C CB    . ASP A 1 457  ? 198.355 309.486 210.546 1.00 67.24  ? 457  ASP A CB    1 
ATOM   3580  C CG    . ASP A 1 457  ? 197.318 310.109 209.631 1.00 67.24  ? 457  ASP A CG    1 
ATOM   3581  O OD1   . ASP A 1 457  ? 197.575 310.202 208.412 1.00 67.24  ? 457  ASP A OD1   1 
ATOM   3582  O OD2   . ASP A 1 457  ? 196.244 310.505 210.131 1.00 67.24  ? 457  ASP A OD2   1 
ATOM   3583  N N     . LYS A 1 458  ? 199.774 312.311 211.401 1.00 59.49  ? 458  LYS A N     1 
ATOM   3584  C CA    . LYS A 1 458  ? 199.701 313.764 211.441 1.00 59.49  ? 458  LYS A CA    1 
ATOM   3585  C C     . LYS A 1 458  ? 201.071 314.428 211.341 1.00 59.49  ? 458  LYS A C     1 
ATOM   3586  O O     . LYS A 1 458  ? 201.209 315.603 211.700 1.00 59.49  ? 458  LYS A O     1 
ATOM   3587  C CB    . LYS A 1 458  ? 198.986 314.219 212.715 1.00 59.49  ? 458  LYS A CB    1 
ATOM   3588  C CG    . LYS A 1 458  ? 197.557 313.714 212.834 1.00 59.49  ? 458  LYS A CG    1 
ATOM   3589  C CD    . LYS A 1 458  ? 196.675 314.710 213.568 1.00 59.49  ? 458  LYS A CD    1 
ATOM   3590  C CE    . LYS A 1 458  ? 196.144 315.775 212.623 1.00 59.49  ? 458  LYS A CE    1 
ATOM   3591  N NZ    . LYS A 1 458  ? 195.171 315.215 211.645 1.00 59.49  ? 458  LYS A NZ    1 
ATOM   3592  N N     . GLY A 1 459  ? 202.082 313.705 210.863 1.00 63.46  ? 459  GLY A N     1 
ATOM   3593  C CA    . GLY A 1 459  ? 203.395 314.290 210.674 1.00 63.46  ? 459  GLY A CA    1 
ATOM   3594  C C     . GLY A 1 459  ? 204.198 314.506 211.936 1.00 63.46  ? 459  GLY A C     1 
ATOM   3595  O O     . GLY A 1 459  ? 205.095 315.353 211.947 1.00 63.46  ? 459  GLY A O     1 
ATOM   3596  N N     . ILE A 1 460  ? 203.906 313.767 213.002 1.00 62.94  ? 460  ILE A N     1 
ATOM   3597  C CA    . ILE A 1 460  ? 204.628 313.875 214.266 1.00 62.94  ? 460  ILE A CA    1 
ATOM   3598  C C     . ILE A 1 460  ? 205.288 312.533 214.547 1.00 62.94  ? 460  ILE A C     1 
ATOM   3599  O O     . ILE A 1 460  ? 204.613 311.496 214.568 1.00 62.94  ? 460  ILE A O     1 
ATOM   3600  C CB    . ILE A 1 460  ? 203.703 314.283 215.423 1.00 62.94  ? 460  ILE A CB    1 
ATOM   3601  C CG1   . ILE A 1 460  ? 202.686 315.327 214.954 1.00 62.94  ? 460  ILE A CG1   1 
ATOM   3602  C CG2   . ILE A 1 460  ? 204.519 314.810 216.595 1.00 62.94  ? 460  ILE A CG2   1 
ATOM   3603  C CD1   . ILE A 1 460  ? 201.906 315.975 216.079 1.00 62.94  ? 460  ILE A CD1   1 
ATOM   3604  N N     . TYR A 1 461  ? 206.599 312.552 214.765 1.00 58.87  ? 461  TYR A N     1 
ATOM   3605  C CA    . TYR A 1 461  ? 207.365 311.346 215.054 1.00 58.87  ? 461  TYR A CA    1 
ATOM   3606  C C     . TYR A 1 461  ? 207.705 311.318 216.539 1.00 58.87  ? 461  TYR A C     1 
ATOM   3607  O O     . TYR A 1 461  ? 208.362 312.233 217.047 1.00 58.87  ? 461  TYR A O     1 
ATOM   3608  C CB    . TYR A 1 461  ? 208.637 311.292 214.208 1.00 58.87  ? 461  TYR A CB    1 
ATOM   3609  C CG    . TYR A 1 461  ? 208.380 311.255 212.718 1.00 58.87  ? 461  TYR A CG    1 
ATOM   3610  C CD1   . TYR A 1 461  ? 207.876 310.114 212.109 1.00 58.87  ? 461  TYR A CD1   1 
ATOM   3611  C CD2   . TYR A 1 461  ? 208.639 312.363 211.922 1.00 58.87  ? 461  TYR A CD2   1 
ATOM   3612  C CE1   . TYR A 1 461  ? 207.639 310.076 210.747 1.00 58.87  ? 461  TYR A CE1   1 
ATOM   3613  C CE2   . TYR A 1 461  ? 208.405 312.335 210.560 1.00 58.87  ? 461  TYR A CE2   1 
ATOM   3614  C CZ    . TYR A 1 461  ? 207.905 311.189 209.978 1.00 58.87  ? 461  TYR A CZ    1 
ATOM   3615  O OH    . TYR A 1 461  ? 207.671 311.156 208.623 1.00 58.87  ? 461  TYR A OH    1 
ATOM   3616  N N     . VAL A 1 462  ? 207.260 310.269 217.228 1.00 55.70  ? 462  VAL A N     1 
ATOM   3617  C CA    . VAL A 1 462  ? 207.470 310.099 218.658 1.00 55.70  ? 462  VAL A CA    1 
ATOM   3618  C C     . VAL A 1 462  ? 207.817 308.639 218.927 1.00 55.70  ? 462  VAL A C     1 
ATOM   3619  O O     . VAL A 1 462  ? 207.869 307.810 218.015 1.00 55.70  ? 462  VAL A O     1 
ATOM   3620  C CB    . VAL A 1 462  ? 206.239 310.524 219.486 1.00 55.70  ? 462  VAL A CB    1 
ATOM   3621  C CG1   . VAL A 1 462  ? 206.054 312.034 219.437 1.00 55.70  ? 462  VAL A CG1   1 
ATOM   3622  C CG2   . VAL A 1 462  ? 204.994 309.807 218.988 1.00 55.70  ? 462  VAL A CG2   1 
ATOM   3623  N N     . GLU A 1 463  ? 208.057 308.328 220.198 1.00 54.78  ? 463  GLU A N     1 
ATOM   3624  C CA    . GLU A 1 463  ? 208.361 306.977 220.644 1.00 54.78  ? 463  GLU A CA    1 
ATOM   3625  C C     . GLU A 1 463  ? 207.377 306.571 221.732 1.00 54.78  ? 463  GLU A C     1 
ATOM   3626  O O     . GLU A 1 463  ? 207.037 307.375 222.605 1.00 54.78  ? 463  GLU A O     1 
ATOM   3627  C CB    . GLU A 1 463  ? 209.799 306.872 221.164 1.00 54.78  ? 463  GLU A CB    1 
ATOM   3628  C CG    . GLU A 1 463  ? 210.859 306.914 220.073 1.00 54.78  ? 463  GLU A CG    1 
ATOM   3629  C CD    . GLU A 1 463  ? 211.110 308.316 219.552 1.00 54.78  ? 463  GLU A CD    1 
ATOM   3630  O OE1   . GLU A 1 463  ? 210.658 309.284 220.198 1.00 54.78  ? 463  GLU A OE1   1 
ATOM   3631  O OE2   . GLU A 1 463  ? 211.756 308.449 218.491 1.00 54.78  ? 463  GLU A OE2   1 
ATOM   3632  N N     . THR A 1 464  ? 206.925 305.321 221.677 1.00 53.84  ? 464  THR A N     1 
ATOM   3633  C CA    . THR A 1 464  ? 205.916 304.839 222.607 1.00 53.84  ? 464  THR A CA    1 
ATOM   3634  C C     . THR A 1 464  ? 206.511 304.673 224.006 1.00 53.84  ? 464  THR A C     1 
ATOM   3635  O O     . THR A 1 464  ? 207.697 304.917 224.248 1.00 53.84  ? 464  THR A O     1 
ATOM   3636  C CB    . THR A 1 464  ? 205.324 303.521 222.112 1.00 53.84  ? 464  THR A CB    1 
ATOM   3637  O OG1   . THR A 1 464  ? 204.246 303.127 222.970 1.00 53.84  ? 464  THR A OG1   1 
ATOM   3638  C CG2   . THR A 1 464  ? 206.385 302.430 222.105 1.00 53.84  ? 464  THR A CG2   1 
ATOM   3639  N N     . ILE A 1 465  ? 205.658 304.251 224.943 1.00 55.23  ? 465  ILE A N     1 
ATOM   3640  C CA    . ILE A 1 465  ? 206.109 304.001 226.310 1.00 55.23  ? 465  ILE A CA    1 
ATOM   3641  C C     . ILE A 1 465  ? 207.115 302.857 226.334 1.00 55.23  ? 465  ILE A C     1 
ATOM   3642  O O     . ILE A 1 465  ? 208.084 302.876 227.103 1.00 55.23  ? 465  ILE A O     1 
ATOM   3643  C CB    . ILE A 1 465  ? 204.898 303.727 227.225 1.00 55.23  ? 465  ILE A CB    1 
ATOM   3644  C CG1   . ILE A 1 465  ? 204.365 305.038 227.808 1.00 55.23  ? 465  ILE A CG1   1 
ATOM   3645  C CG2   . ILE A 1 465  ? 205.255 302.752 228.340 1.00 55.23  ? 465  ILE A CG2   1 
ATOM   3646  C CD1   . ILE A 1 465  ? 205.284 305.672 228.830 1.00 55.23  ? 465  ILE A CD1   1 
ATOM   3647  N N     . ALA A 1 466  ? 206.917 301.859 225.478 1.00 52.59  ? 466  ALA A N     1 
ATOM   3648  C CA    . ALA A 1 466  ? 207.851 300.750 225.371 1.00 52.59  ? 466  ALA A CA    1 
ATOM   3649  C C     . ALA A 1 466  ? 209.089 301.181 224.585 1.00 52.59  ? 466  ALA A C     1 
ATOM   3650  O O     . ALA A 1 466  ? 209.319 302.366 224.331 1.00 52.59  ? 466  ALA A O     1 
ATOM   3651  C CB    . ALA A 1 466  ? 207.175 299.547 224.718 1.00 52.59  ? 466  ALA A CB    1 
ATOM   3652  N N     . GLU A 1 467  ? 209.920 300.194 224.238 1.00 61.89  ? 467  GLU A N     1 
ATOM   3653  C CA    . GLU A 1 467  ? 211.152 300.318 223.455 1.00 61.89  ? 467  GLU A CA    1 
ATOM   3654  C C     . GLU A 1 467  ? 212.118 301.357 224.015 1.00 61.89  ? 467  GLU A C     1 
ATOM   3655  O O     . GLU A 1 467  ? 213.047 301.774 223.311 1.00 61.89  ? 467  GLU A O     1 
ATOM   3656  C CB    . GLU A 1 467  ? 210.873 300.607 221.970 1.00 61.89  ? 467  GLU A CB    1 
ATOM   3657  C CG    . GLU A 1 467  ? 210.459 302.031 221.614 1.00 61.89  ? 467  GLU A CG    1 
ATOM   3658  C CD    . GLU A 1 467  ? 210.546 302.311 220.126 1.00 61.89  ? 467  GLU A CD    1 
ATOM   3659  O OE1   . GLU A 1 467  ? 210.757 301.355 219.351 1.00 61.89  ? 467  GLU A OE1   1 
ATOM   3660  O OE2   . GLU A 1 467  ? 210.403 303.487 219.732 1.00 61.89  ? 467  GLU A OE2   1 
ATOM   3661  N N     . VAL A 1 468  ? 211.940 301.773 225.268 1.00 52.18  ? 468  VAL A N     1 
ATOM   3662  C CA    . VAL A 1 468  ? 212.832 302.731 225.912 1.00 52.18  ? 468  VAL A CA    1 
ATOM   3663  C C     . VAL A 1 468  ? 213.318 302.114 227.220 1.00 52.18  ? 468  VAL A C     1 
ATOM   3664  O O     . VAL A 1 468  ? 213.658 302.822 228.175 1.00 52.18  ? 468  VAL A O     1 
ATOM   3665  C CB    . VAL A 1 468  ? 212.126 304.090 226.113 1.00 52.18  ? 468  VAL A CB    1 
ATOM   3666  C CG1   . VAL A 1 468  ? 211.078 304.022 227.225 1.00 52.18  ? 468  VAL A CG1   1 
ATOM   3667  C CG2   . VAL A 1 468  ? 213.137 305.213 226.348 1.00 52.18  ? 468  VAL A CG2   1 
ATOM   3668  N N     . TYR A 1 469  ? 213.392 300.778 227.242 1.00 55.12  ? 469  TYR A N     1 
ATOM   3669  C CA    . TYR A 1 469  ? 213.709 299.986 228.438 1.00 55.12  ? 469  TYR A CA    1 
ATOM   3670  C C     . TYR A 1 469  ? 214.785 300.574 229.347 1.00 55.12  ? 469  TYR A C     1 
ATOM   3671  O O     . TYR A 1 469  ? 214.597 300.540 230.570 1.00 55.12  ? 469  TYR A O     1 
ATOM   3672  C CB    . TYR A 1 469  ? 214.099 298.568 227.990 1.00 55.12  ? 469  TYR A CB    1 
ATOM   3673  C CG    . TYR A 1 469  ? 213.990 297.515 229.072 1.00 55.12  ? 469  TYR A CG    1 
ATOM   3674  C CD1   . TYR A 1 469  ? 213.257 297.748 230.229 1.00 55.12  ? 469  TYR A CD1   1 
ATOM   3675  C CD2   . TYR A 1 469  ? 214.622 296.286 228.935 1.00 55.12  ? 469  TYR A CD2   1 
ATOM   3676  C CE1   . TYR A 1 469  ? 213.156 296.788 231.218 1.00 55.12  ? 469  TYR A CE1   1 
ATOM   3677  C CE2   . TYR A 1 469  ? 214.527 295.319 229.918 1.00 55.12  ? 469  TYR A CE2   1 
ATOM   3678  C CZ    . TYR A 1 469  ? 213.793 295.575 231.057 1.00 55.12  ? 469  TYR A CZ    1 
ATOM   3679  O OH    . TYR A 1 469  ? 213.696 294.616 232.038 1.00 55.12  ? 469  TYR A OH    1 
ATOM   3680  N N     . PRO A 1 470  ? 215.912 301.103 228.852 1.00 54.11  ? 470  PRO A N     1 
ATOM   3681  C CA    . PRO A 1 470  ? 216.872 301.731 229.779 1.00 54.11  ? 470  PRO A CA    1 
ATOM   3682  C C     . PRO A 1 470  ? 216.294 302.901 230.558 1.00 54.11  ? 470  PRO A C     1 
ATOM   3683  O O     . PRO A 1 470  ? 216.793 303.212 231.647 1.00 54.11  ? 470  PRO A O     1 
ATOM   3684  C CB    . PRO A 1 470  ? 218.018 302.179 228.857 1.00 54.11  ? 470  PRO A CB    1 
ATOM   3685  C CG    . PRO A 1 470  ? 217.465 302.119 227.470 1.00 54.11  ? 470  PRO A CG    1 
ATOM   3686  C CD    . PRO A 1 470  ? 216.465 301.017 227.489 1.00 54.11  ? 470  PRO A CD    1 
ATOM   3687  N N     . ILE A 1 471  ? 215.260 303.559 230.039 1.00 48.15  ? 471  ILE A N     1 
ATOM   3688  C CA    . ILE A 1 471  ? 214.637 304.696 230.706 1.00 48.15  ? 471  ILE A CA    1 
ATOM   3689  C C     . ILE A 1 471  ? 213.264 304.278 231.214 1.00 48.15  ? 471  ILE A C     1 
ATOM   3690  O O     . ILE A 1 471  ? 212.565 303.469 230.593 1.00 48.15  ? 471  ILE A O     1 
ATOM   3691  C CB    . ILE A 1 471  ? 214.526 305.918 229.769 1.00 48.15  ? 471  ILE A CB    1 
ATOM   3692  C CG1   . ILE A 1 471  ? 215.772 306.037 228.887 1.00 48.15  ? 471  ILE A CG1   1 
ATOM   3693  C CG2   . ILE A 1 471  ? 214.322 307.193 230.572 1.00 48.15  ? 471  ILE A CG2   1 
ATOM   3694  C CD1   . ILE A 1 471  ? 217.054 306.276 229.659 1.00 48.15  ? 471  ILE A CD1   1 
ATOM   3695  N N     . ARG A 1 472  ? 212.877 304.836 232.359 1.00 42.88  ? 472  ARG A N     1 
ATOM   3696  C CA    . ARG A 1 472  ? 211.580 304.567 232.960 1.00 42.88  ? 472  ARG A CA    1 
ATOM   3697  C C     . ARG A 1 472  ? 210.855 305.879 233.225 1.00 42.88  ? 472  ARG A C     1 
ATOM   3698  O O     . ARG A 1 472  ? 211.468 306.881 233.603 1.00 42.88  ? 472  ARG A O     1 
ATOM   3699  C CB    . ARG A 1 472  ? 211.714 303.770 234.265 1.00 42.88  ? 472  ARG A CB    1 
ATOM   3700  C CG    . ARG A 1 472  ? 212.132 302.322 234.067 1.00 42.88  ? 472  ARG A CG    1 
ATOM   3701  C CD    . ARG A 1 472  ? 213.484 302.043 234.703 1.00 42.88  ? 472  ARG A CD    1 
ATOM   3702  N NE    . ARG A 1 472  ? 214.139 300.878 234.119 1.00 42.88  ? 472  ARG A NE    1 
ATOM   3703  C CZ    . ARG A 1 472  ? 213.779 299.621 234.342 1.00 42.88  ? 472  ARG A CZ    1 
ATOM   3704  N NH1   . ARG A 1 472  ? 212.773 299.322 235.147 1.00 42.88  ? 472  ARG A NH1   1 
ATOM   3705  N NH2   . ARG A 1 472  ? 214.449 298.640 233.745 1.00 42.88  ? 472  ARG A NH2   1 
ATOM   3706  N N     . VAL A 1 473  ? 209.541 305.861 233.020 1.00 36.43  ? 473  VAL A N     1 
ATOM   3707  C CA    . VAL A 1 473  ? 208.693 307.036 233.186 1.00 36.43  ? 473  VAL A CA    1 
ATOM   3708  C C     . VAL A 1 473  ? 207.689 306.743 234.292 1.00 36.43  ? 473  VAL A C     1 
ATOM   3709  O O     . VAL A 1 473  ? 206.925 305.774 234.203 1.00 36.43  ? 473  VAL A O     1 
ATOM   3710  C CB    . VAL A 1 473  ? 207.976 307.410 231.880 1.00 36.43  ? 473  VAL A CB    1 
ATOM   3711  C CG1   . VAL A 1 473  ? 207.271 308.747 232.027 1.00 36.43  ? 473  VAL A CG1   1 
ATOM   3712  C CG2   . VAL A 1 473  ? 208.962 307.446 230.722 1.00 36.43  ? 473  VAL A CG2   1 
ATOM   3713  N N     . GLN A 1 474  ? 207.691 307.575 235.325 1.00 32.35  ? 474  GLN A N     1 
ATOM   3714  C CA    . GLN A 1 474  ? 206.793 307.444 236.461 1.00 32.35  ? 474  GLN A CA    1 
ATOM   3715  C C     . GLN A 1 474  ? 206.298 308.825 236.858 1.00 32.35  ? 474  GLN A C     1 
ATOM   3716  O O     . GLN A 1 474  ? 206.966 309.830 236.590 1.00 32.35  ? 474  GLN A O     1 
ATOM   3717  C CB    . GLN A 1 474  ? 207.485 306.770 237.654 1.00 32.35  ? 474  GLN A CB    1 
ATOM   3718  C CG    . GLN A 1 474  ? 207.983 305.360 237.377 1.00 32.35  ? 474  GLN A CG    1 
ATOM   3719  C CD    . GLN A 1 474  ? 206.970 304.299 237.761 1.00 32.35  ? 474  GLN A CD    1 
ATOM   3720  O OE1   . GLN A 1 474  ? 205.778 304.580 237.887 1.00 32.35  ? 474  GLN A OE1   1 
ATOM   3721  N NE2   . GLN A 1 474  ? 207.440 303.072 237.950 1.00 32.35  ? 474  GLN A NE2   1 
ATOM   3722  N N     . PRO A 1 475  ? 205.129 308.909 237.492 1.00 35.53  ? 475  PRO A N     1 
ATOM   3723  C CA    . PRO A 1 475  ? 204.624 310.212 237.943 1.00 35.53  ? 475  PRO A CA    1 
ATOM   3724  C C     . PRO A 1 475  ? 205.485 310.790 239.057 1.00 35.53  ? 475  PRO A C     1 
ATOM   3725  O O     . PRO A 1 475  ? 206.319 310.115 239.664 1.00 35.53  ? 475  PRO A O     1 
ATOM   3726  C CB    . PRO A 1 475  ? 203.204 309.902 238.433 1.00 35.53  ? 475  PRO A CB    1 
ATOM   3727  C CG    . PRO A 1 475  ? 202.855 308.584 237.820 1.00 35.53  ? 475  PRO A CG    1 
ATOM   3728  C CD    . PRO A 1 475  ? 204.142 307.835 237.691 1.00 35.53  ? 475  PRO A CD    1 
ATOM   3729  N N     . ALA A 1 476  ? 205.266 312.080 239.324 1.00 36.93  ? 476  ALA A N     1 
ATOM   3730  C CA    . ALA A 1 476  ? 206.045 312.793 240.329 1.00 36.93  ? 476  ALA A CA    1 
ATOM   3731  C C     . ALA A 1 476  ? 205.748 312.332 241.751 1.00 36.93  ? 476  ALA A C     1 
ATOM   3732  O O     . ALA A 1 476  ? 206.535 312.625 242.658 1.00 36.93  ? 476  ALA A O     1 
ATOM   3733  C CB    . ALA A 1 476  ? 205.796 314.298 240.218 1.00 36.93  ? 476  ALA A CB    1 
ATOM   3734  N N     . ARG A 1 477  ? 204.633 311.628 241.967 1.00 39.95  ? 477  ARG A N     1 
ATOM   3735  C CA    . ARG A 1 477  ? 204.330 311.116 243.300 1.00 39.95  ? 477  ARG A CA    1 
ATOM   3736  C C     . ARG A 1 477  ? 205.380 310.110 243.754 1.00 39.95  ? 477  ARG A C     1 
ATOM   3737  O O     . ARG A 1 477  ? 205.771 310.095 244.927 1.00 39.95  ? 477  ARG A O     1 
ATOM   3738  C CB    . ARG A 1 477  ? 202.937 310.488 243.315 1.00 39.95  ? 477  ARG A CB    1 
ATOM   3739  C CG    . ARG A 1 477  ? 201.813 311.467 243.016 1.00 39.95  ? 477  ARG A CG    1 
ATOM   3740  C CD    . ARG A 1 477  ? 200.444 310.841 243.244 1.00 39.95  ? 477  ARG A CD    1 
ATOM   3741  N NE    . ARG A 1 477  ? 199.973 310.104 242.077 1.00 39.95  ? 477  ARG A NE    1 
ATOM   3742  C CZ    . ARG A 1 477  ? 200.147 308.803 241.889 1.00 39.95  ? 477  ARG A CZ    1 
ATOM   3743  N NH1   . ARG A 1 477  ? 200.774 308.053 242.780 1.00 39.95  ? 477  ARG A NH1   1 
ATOM   3744  N NH2   . ARG A 1 477  ? 199.678 308.240 240.779 1.00 39.95  ? 477  ARG A NH2   1 
ATOM   3745  N N     . ILE A 1 478  ? 205.847 309.261 242.836 1.00 35.64  ? 478  ILE A N     1 
ATOM   3746  C CA    . ILE A 1 478  ? 206.905 308.310 243.168 1.00 35.64  ? 478  ILE A CA    1 
ATOM   3747  C C     . ILE A 1 478  ? 208.180 309.048 243.555 1.00 35.64  ? 478  ILE A C     1 
ATOM   3748  O O     . ILE A 1 478  ? 208.869 308.670 244.510 1.00 35.64  ? 478  ILE A O     1 
ATOM   3749  C CB    . ILE A 1 478  ? 207.143 307.342 241.993 1.00 35.64  ? 478  ILE A CB    1 
ATOM   3750  C CG1   . ILE A 1 478  ? 205.827 306.698 241.549 1.00 35.64  ? 478  ILE A CG1   1 
ATOM   3751  C CG2   . ILE A 1 478  ? 208.155 306.275 242.378 1.00 35.64  ? 478  ILE A CG2   1 
ATOM   3752  C CD1   . ILE A 1 478  ? 205.036 306.067 242.677 1.00 35.64  ? 478  ILE A CD1   1 
ATOM   3753  N N     . LEU A 1 479  ? 208.512 310.107 242.822 1.00 34.58  ? 479  LEU A N     1 
ATOM   3754  C CA    . LEU A 1 479  ? 209.682 310.925 243.125 1.00 34.58  ? 479  LEU A CA    1 
ATOM   3755  C C     . LEU A 1 479  ? 209.573 311.556 244.510 1.00 34.58  ? 479  LEU A C     1 
ATOM   3756  O O     . LEU A 1 479  ? 210.543 311.584 245.269 1.00 34.58  ? 479  LEU A O     1 
ATOM   3757  C CB    . LEU A 1 479  ? 209.859 312.015 242.065 1.00 34.58  ? 479  LEU A CB    1 
ATOM   3758  C CG    . LEU A 1 479  ? 210.968 313.040 242.312 1.00 34.58  ? 479  LEU A CG    1 
ATOM   3759  C CD1   . LEU A 1 479  ? 212.318 312.355 242.463 1.00 34.58  ? 479  LEU A CD1   1 
ATOM   3760  C CD2   . LEU A 1 479  ? 211.004 314.071 241.194 1.00 34.58  ? 479  LEU A CD2   1 
HETATM 3761  N N     . SEP A 1 480  ? 208.385 312.059 244.830 1.00 35.04  ? 480  SEP A N     1 
HETATM 3762  C CA    . SEP A 1 480  ? 208.134 312.663 246.134 1.00 35.04  ? 480  SEP A CA    1 
HETATM 3763  C CB    . SEP A 1 480  ? 206.734 313.277 246.181 1.00 35.04  ? 480  SEP A CB    1 
HETATM 3764  C C     . SEP A 1 480  ? 208.295 311.637 247.252 1.00 35.04  ? 480  SEP A C     1 
HETATM 3765  O O     . SEP A 1 480  ? 208.921 311.913 248.277 1.00 35.04  ? 480  SEP A O     1 
ATOM   3766  N N     . HIS A 1 481  ? 207.734 310.450 247.044 1.00 37.17  ? 481  HIS A N     1 
ATOM   3767  C CA    . HIS A 1 481  ? 207.828 309.374 248.025 1.00 37.17  ? 481  HIS A CA    1 
ATOM   3768  C C     . HIS A 1 481  ? 209.280 308.948 248.237 1.00 37.17  ? 481  HIS A C     1 
ATOM   3769  O O     . HIS A 1 481  ? 209.691 308.655 249.360 1.00 37.17  ? 481  HIS A O     1 
ATOM   3770  C CB    . HIS A 1 481  ? 206.983 308.176 247.587 1.00 37.17  ? 481  HIS A CB    1 
ATOM   3771  C CG    . HIS A 1 481  ? 205.508 308.404 247.703 1.00 37.17  ? 481  HIS A CG    1 
ATOM   3772  N ND1   . HIS A 1 481  ? 204.949 309.158 248.712 1.00 37.17  ? 481  HIS A ND1   1 
ATOM   3773  C CD2   . HIS A 1 481  ? 204.476 307.979 246.936 1.00 37.17  ? 481  HIS A CD2   1 
ATOM   3774  C CE1   . HIS A 1 481  ? 203.636 309.187 248.562 1.00 37.17  ? 481  HIS A CE1   1 
ATOM   3775  N NE2   . HIS A 1 481  ? 203.324 308.479 247.492 1.00 37.17  ? 481  HIS A NE2   1 
ATOM   3776  N N     . ILE A 1 482  ? 210.049 308.910 247.146 1.00 31.22  ? 482  ILE A N     1 
ATOM   3777  C CA    . ILE A 1 482  ? 211.463 308.556 247.243 1.00 31.22  ? 482  ILE A CA    1 
ATOM   3778  C C     . ILE A 1 482  ? 212.230 309.624 248.013 1.00 31.22  ? 482  ILE A C     1 
ATOM   3779  O O     . ILE A 1 482  ? 213.034 309.313 248.902 1.00 31.22  ? 482  ILE A O     1 
ATOM   3780  C CB    . ILE A 1 482  ? 212.056 308.331 245.840 1.00 31.22  ? 482  ILE A CB    1 
ATOM   3781  C CG1   . ILE A 1 482  ? 211.561 307.005 245.258 1.00 31.22  ? 482  ILE A CG1   1 
ATOM   3782  C CG2   . ILE A 1 482  ? 213.576 308.359 245.887 1.00 31.22  ? 482  ILE A CG2   1 
ATOM   3783  C CD1   . ILE A 1 482  ? 211.623 306.942 243.748 1.00 31.22  ? 482  ILE A CD1   1 
ATOM   3784  N N     . TYR A 1 483  ? 211.993 310.898 247.691 1.00 36.55  ? 483  TYR A N     1 
ATOM   3785  C CA    . TYR A 1 483  ? 212.693 311.975 248.385 1.00 36.55  ? 483  TYR A CA    1 
ATOM   3786  C C     . TYR A 1 483  ? 212.274 312.071 249.847 1.00 36.55  ? 483  TYR A C     1 
ATOM   3787  O O     . TYR A 1 483  ? 213.019 312.613 250.671 1.00 36.55  ? 483  TYR A O     1 
ATOM   3788  C CB    . TYR A 1 483  ? 212.456 313.307 247.670 1.00 36.55  ? 483  TYR A CB    1 
ATOM   3789  C CG    . TYR A 1 483  ? 213.691 313.862 246.994 1.00 36.55  ? 483  TYR A CG    1 
ATOM   3790  C CD1   . TYR A 1 483  ? 214.690 314.483 247.733 1.00 36.55  ? 483  TYR A CD1   1 
ATOM   3791  C CD2   . TYR A 1 483  ? 213.861 313.761 245.619 1.00 36.55  ? 483  TYR A CD2   1 
ATOM   3792  C CE1   . TYR A 1 483  ? 215.820 314.989 247.122 1.00 36.55  ? 483  TYR A CE1   1 
ATOM   3793  C CE2   . TYR A 1 483  ? 214.989 314.264 244.999 1.00 36.55  ? 483  TYR A CE2   1 
ATOM   3794  C CZ    . TYR A 1 483  ? 215.967 314.878 245.756 1.00 36.55  ? 483  TYR A CZ    1 
ATOM   3795  O OH    . TYR A 1 483  ? 217.091 315.381 245.146 1.00 36.55  ? 483  TYR A OH    1 
ATOM   3796  N N     . SER A 1 484  ? 211.088 311.559 250.187 1.00 40.24  ? 484  SER A N     1 
ATOM   3797  C CA    . SER A 1 484  ? 210.652 311.563 251.579 1.00 40.24  ? 484  SER A CA    1 
ATOM   3798  C C     . SER A 1 484  ? 211.508 310.664 252.463 1.00 40.24  ? 484  SER A C     1 
ATOM   3799  O O     . SER A 1 484  ? 211.478 310.811 253.690 1.00 40.24  ? 484  SER A O     1 
ATOM   3800  C CB    . SER A 1 484  ? 209.188 311.134 251.670 1.00 40.24  ? 484  SER A CB    1 
ATOM   3801  O OG    . SER A 1 484  ? 208.939 310.435 252.877 1.00 40.24  ? 484  SER A OG    1 
ATOM   3802  N N     . SER A 1 485  ? 212.265 309.737 251.874 1.00 38.00  ? 485  SER A N     1 
ATOM   3803  C CA    . SER A 1 485  ? 213.112 308.816 252.622 1.00 38.00  ? 485  SER A CA    1 
ATOM   3804  C C     . SER A 1 485  ? 214.580 309.234 252.612 1.00 38.00  ? 485  SER A C     1 
ATOM   3805  O O     . SER A 1 485  ? 215.468 308.376 252.675 1.00 38.00  ? 485  SER A O     1 
ATOM   3806  C CB    . SER A 1 485  ? 212.969 307.396 252.072 1.00 38.00  ? 485  SER A CB    1 
ATOM   3807  O OG    . SER A 1 485  ? 211.615 306.978 252.051 1.00 38.00  ? 485  SER A OG    1 
ATOM   3808  N N     . LEU A 1 486  ? 214.856 310.532 252.531 1.00 40.74  ? 486  LEU A N     1 
ATOM   3809  C CA    . LEU A 1 486  ? 216.219 311.049 252.552 1.00 40.74  ? 486  LEU A CA    1 
ATOM   3810  C C     . LEU A 1 486  ? 216.492 311.693 253.903 1.00 40.74  ? 486  LEU A C     1 
ATOM   3811  O O     . LEU A 1 486  ? 215.629 312.388 254.450 1.00 40.74  ? 486  LEU A O     1 
ATOM   3812  C CB    . LEU A 1 486  ? 216.448 312.052 251.417 1.00 40.74  ? 486  LEU A CB    1 
ATOM   3813  C CG    . LEU A 1 486  ? 217.739 312.878 251.443 1.00 40.74  ? 486  LEU A CG    1 
ATOM   3814  C CD1   . LEU A 1 486  ? 218.855 312.178 250.710 1.00 40.74  ? 486  LEU A CD1   1 
ATOM   3815  C CD2   . LEU A 1 486  ? 217.488 314.226 250.796 1.00 40.74  ? 486  LEU A CD2   1 
ATOM   3816  N N     . GLY A 1 487  ? 217.685 311.456 254.439 1.00 41.92  ? 487  GLY A N     1 
ATOM   3817  C CA    . GLY A 1 487  ? 218.000 311.936 255.775 1.00 41.92  ? 487  GLY A CA    1 
ATOM   3818  C C     . GLY A 1 487  ? 217.201 311.253 256.862 1.00 41.92  ? 487  GLY A C     1 
ATOM   3819  O O     . GLY A 1 487  ? 216.726 311.917 257.792 1.00 41.92  ? 487  GLY A O     1 
ATOM   3820  N N     . CYS A 1 488  ? 217.040 309.936 256.765 1.00 49.05  ? 488  CYS A N     1 
ATOM   3821  C CA    . CYS A 1 488  ? 216.299 309.156 257.746 1.00 49.05  ? 488  CYS A CA    1 
ATOM   3822  C C     . CYS A 1 488  ? 217.269 308.387 258.632 1.00 49.05  ? 488  CYS A C     1 
ATOM   3823  O O     . CYS A 1 488  ? 218.131 307.657 258.131 1.00 49.05  ? 488  CYS A O     1 
ATOM   3824  C CB    . CYS A 1 488  ? 215.332 308.190 257.060 1.00 49.05  ? 488  CYS A CB    1 
ATOM   3825  S SG    . CYS A 1 488  ? 213.643 308.812 256.873 1.00 49.05  ? 488  CYS A SG    1 
ATOM   3826  N N     . ASN A 1 489  ? 217.127 308.554 259.944 1.00 46.52  ? 489  ASN A N     1 
ATOM   3827  C CA    . ASN A 1 489  ? 217.947 307.849 260.917 1.00 46.52  ? 489  ASN A CA    1 
ATOM   3828  C C     . ASN A 1 489  ? 217.066 307.326 262.041 1.00 46.52  ? 489  ASN A C     1 
ATOM   3829  O O     . ASN A 1 489  ? 216.144 308.013 262.490 1.00 46.52  ? 489  ASN A O     1 
ATOM   3830  C CB    . ASN A 1 489  ? 219.043 308.755 261.486 1.00 46.52  ? 489  ASN A CB    1 
ATOM   3831  C CG    . ASN A 1 489  ? 220.343 308.016 261.718 1.00 46.52  ? 489  ASN A CG    1 
ATOM   3832  O OD1   . ASN A 1 489  ? 220.352 306.804 261.929 1.00 46.52  ? 489  ASN A OD1   1 
ATOM   3833  N ND2   . ASN A 1 489  ? 221.453 308.744 261.678 1.00 46.52  ? 489  ASN A ND2   1 
ATOM   3834  N N     . ASN A 1 490  ? 217.354 306.104 262.489 1.00 50.63  ? 490  ASN A N     1 
ATOM   3835  C CA    . ASN A 1 490  ? 216.592 305.490 263.570 1.00 50.63  ? 490  ASN A CA    1 
ATOM   3836  C C     . ASN A 1 490  ? 217.247 305.694 264.930 1.00 50.63  ? 490  ASN A C     1 
ATOM   3837  O O     . ASN A 1 490  ? 216.545 305.835 265.938 1.00 50.63  ? 490  ASN A O     1 
ATOM   3838  C CB    . ASN A 1 490  ? 216.408 303.994 263.301 1.00 50.63  ? 490  ASN A CB    1 
ATOM   3839  C CG    . ASN A 1 490  ? 215.000 303.519 263.598 1.00 50.63  ? 490  ASN A CG    1 
ATOM   3840  O OD1   . ASN A 1 490  ? 214.339 304.029 264.503 1.00 50.63  ? 490  ASN A OD1   1 
ATOM   3841  N ND2   . ASN A 1 490  ? 214.533 302.538 262.836 1.00 50.63  ? 490  ASN A ND2   1 
ATOM   3842  N N     . ARG A 1 491  ? 218.582 305.704 264.981 1.00 51.60  ? 491  ARG A N     1 
ATOM   3843  C CA    . ARG A 1 491  ? 219.271 305.919 266.250 1.00 51.60  ? 491  ARG A CA    1 
ATOM   3844  C C     . ARG A 1 491  ? 218.992 307.311 266.802 1.00 51.60  ? 491  ARG A C     1 
ATOM   3845  O O     . ARG A 1 491  ? 218.767 307.477 268.006 1.00 51.60  ? 491  ARG A O     1 
ATOM   3846  C CB    . ARG A 1 491  ? 220.774 305.701 266.074 1.00 51.60  ? 491  ARG A CB    1 
ATOM   3847  C CG    . ARG A 1 491  ? 221.541 305.568 267.380 1.00 51.60  ? 491  ARG A CG    1 
ATOM   3848  C CD    . ARG A 1 491  ? 223.029 305.379 267.128 1.00 51.60  ? 491  ARG A CD    1 
ATOM   3849  N NE    . ARG A 1 491  ? 223.708 304.783 268.272 1.00 51.60  ? 491  ARG A NE    1 
ATOM   3850  C CZ    . ARG A 1 491  ? 224.666 303.870 268.183 1.00 51.60  ? 491  ARG A CZ    1 
ATOM   3851  N NH1   . ARG A 1 491  ? 225.084 303.419 267.011 1.00 51.60  ? 491  ARG A NH1   1 
ATOM   3852  N NH2   . ARG A 1 491  ? 225.217 303.396 269.297 1.00 51.60  ? 491  ARG A NH2   1 
ATOM   3853  N N     . MET A 1 492  ? 219.001 308.323 265.937 1.00 49.74  ? 492  MET A N     1 
ATOM   3854  C CA    . MET A 1 492  ? 218.730 309.696 266.339 1.00 49.74  ? 492  MET A CA    1 
ATOM   3855  C C     . MET A 1 492  ? 217.259 310.071 266.218 1.00 49.74  ? 492  MET A C     1 
ATOM   3856  O O     . MET A 1 492  ? 216.904 311.219 266.508 1.00 49.74  ? 492  MET A O     1 
ATOM   3857  C CB    . MET A 1 492  ? 219.578 310.665 265.507 1.00 49.74  ? 492  MET A CB    1 
ATOM   3858  C CG    . MET A 1 492  ? 221.030 310.751 265.947 1.00 49.74  ? 492  MET A CG    1 
ATOM   3859  S SD    . MET A 1 492  ? 222.008 311.860 264.915 1.00 49.74  ? 492  MET A SD    1 
ATOM   3860  C CE    . MET A 1 492  ? 222.311 313.206 266.057 1.00 49.74  ? 492  MET A CE    1 
ATOM   3861  N N     . LYS A 1 493  ? 216.405 309.136 265.797 1.00 46.92  ? 493  LYS A N     1 
ATOM   3862  C CA    . LYS A 1 493  ? 214.964 309.358 265.666 1.00 46.92  ? 493  LYS A CA    1 
ATOM   3863  C C     . LYS A 1 493  ? 214.669 310.512 264.704 1.00 46.92  ? 493  LYS A C     1 
ATOM   3864  O O     . LYS A 1 493  ? 214.059 311.522 265.061 1.00 46.92  ? 493  LYS A O     1 
ATOM   3865  C CB    . LYS A 1 493  ? 214.317 309.596 267.035 1.00 46.92  ? 493  LYS A CB    1 
ATOM   3866  C CG    . LYS A 1 493  ? 214.617 308.514 268.059 1.00 46.92  ? 493  LYS A CG    1 
ATOM   3867  C CD    . LYS A 1 493  ? 214.099 308.896 269.436 1.00 46.92  ? 493  LYS A CD    1 
ATOM   3868  C CE    . LYS A 1 493  ? 212.579 308.934 269.462 1.00 46.92  ? 493  LYS A CE    1 
ATOM   3869  N NZ    . LYS A 1 493  ? 211.983 307.640 269.029 1.00 46.92  ? 493  LYS A NZ    1 
ATOM   3870  N N     . LEU A 1 494  ? 215.118 310.340 263.464 1.00 42.50  ? 494  LEU A N     1 
ATOM   3871  C CA    . LEU A 1 494  ? 214.890 311.305 262.397 1.00 42.50  ? 494  LEU A CA    1 
ATOM   3872  C C     . LEU A 1 494  ? 213.934 310.704 261.375 1.00 42.50  ? 494  LEU A C     1 
ATOM   3873  O O     . LEU A 1 494  ? 214.162 309.593 260.883 1.00 42.50  ? 494  LEU A O     1 
ATOM   3874  C CB    . LEU A 1 494  ? 216.206 311.706 261.727 1.00 42.50  ? 494  LEU A CB    1 
ATOM   3875  C CG    . LEU A 1 494  ? 217.245 312.367 262.635 1.00 42.50  ? 494  LEU A CG    1 
ATOM   3876  C CD1   . LEU A 1 494  ? 218.612 312.389 261.968 1.00 42.50  ? 494  LEU A CD1   1 
ATOM   3877  C CD2   . LEU A 1 494  ? 216.809 313.774 263.018 1.00 42.50  ? 494  LEU A CD2   1 
ATOM   3878  N N     . SER A 1 495  ? 212.869 311.438 261.060 1.00 42.38  ? 495  SER A N     1 
ATOM   3879  C CA    . SER A 1 495  ? 211.824 310.954 260.168 1.00 42.38  ? 495  SER A CA    1 
ATOM   3880  C C     . SER A 1 495  ? 212.053 311.332 258.710 1.00 42.38  ? 495  SER A C     1 
ATOM   3881  O O     . SER A 1 495  ? 211.242 310.959 257.856 1.00 42.38  ? 495  SER A O     1 
ATOM   3882  C CB    . SER A 1 495  ? 210.459 311.481 260.625 1.00 42.38  ? 495  SER A CB    1 
ATOM   3883  O OG    . SER A 1 495  ? 210.060 310.877 261.843 1.00 42.38  ? 495  SER A OG    1 
ATOM   3884  N N     . GLY A 1 496  ? 213.124 312.054 258.403 1.00 43.66  ? 496  GLY A N     1 
ATOM   3885  C CA    . GLY A 1 496  ? 213.405 312.428 257.034 1.00 43.66  ? 496  GLY A CA    1 
ATOM   3886  C C     . GLY A 1 496  ? 212.567 313.600 256.559 1.00 43.66  ? 496  GLY A C     1 
ATOM   3887  O O     . GLY A 1 496  ? 211.864 314.268 257.323 1.00 43.66  ? 496  GLY A O     1 
ATOM   3888  N N     . ARG A 1 497  ? 212.655 313.848 255.257 1.00 41.52  ? 497  ARG A N     1 
ATOM   3889  C CA    . ARG A 1 497  ? 211.947 314.974 254.659 1.00 41.52  ? 497  ARG A CA    1 
ATOM   3890  C C     . ARG A 1 497  ? 210.443 314.727 254.689 1.00 41.52  ? 497  ARG A C     1 
ATOM   3891  O O     . ARG A 1 497  ? 209.988 313.654 254.276 1.00 41.52  ? 497  ARG A O     1 
ATOM   3892  C CB    . ARG A 1 497  ? 212.414 315.195 253.223 1.00 41.52  ? 497  ARG A CB    1 
ATOM   3893  C CG    . ARG A 1 497  ? 211.531 316.129 252.414 1.00 41.52  ? 497  ARG A CG    1 
ATOM   3894  C CD    . ARG A 1 497  ? 212.299 316.741 251.251 1.00 41.52  ? 497  ARG A CD    1 
ATOM   3895  N NE    . ARG A 1 497  ? 211.518 317.746 250.539 1.00 41.52  ? 497  ARG A NE    1 
ATOM   3896  C CZ    . ARG A 1 497  ? 210.514 317.476 249.715 1.00 41.52  ? 497  ARG A CZ    1 
ATOM   3897  N NH1   . ARG A 1 497  ? 210.144 316.232 249.461 1.00 41.52  ? 497  ARG A NH1   1 
ATOM   3898  N NH2   . ARG A 1 497  ? 209.868 318.480 249.129 1.00 41.52  ? 497  ARG A NH2   1 
ATOM   3899  N N     . PRO A 1 498  ? 209.645 315.679 255.169 1.00 42.60  ? 498  PRO A N     1 
ATOM   3900  C CA    . PRO A 1 498  ? 208.189 315.520 255.099 1.00 42.60  ? 498  PRO A CA    1 
ATOM   3901  C C     . PRO A 1 498  ? 207.708 315.509 253.657 1.00 42.60  ? 498  PRO A C     1 
ATOM   3902  O O     . PRO A 1 498  ? 208.310 316.122 252.771 1.00 42.60  ? 498  PRO A O     1 
ATOM   3903  C CB    . PRO A 1 498  ? 207.655 316.744 255.855 1.00 42.60  ? 498  PRO A CB    1 
ATOM   3904  C CG    . PRO A 1 498  ? 208.829 317.296 256.610 1.00 42.60  ? 498  PRO A CG    1 
ATOM   3905  C CD    . PRO A 1 498  ? 210.038 316.943 255.809 1.00 42.60  ? 498  PRO A CD    1 
ATOM   3906  N N     . TYR A 1 499  ? 206.610 314.793 253.429 1.00 48.73  ? 499  TYR A N     1 
ATOM   3907  C CA    . TYR A 1 499  ? 206.060 314.679 252.084 1.00 48.73  ? 499  TYR A CA    1 
ATOM   3908  C C     . TYR A 1 499  ? 205.616 316.043 251.571 1.00 48.73  ? 499  TYR A C     1 
ATOM   3909  O O     . TYR A 1 499  ? 204.934 316.795 252.275 1.00 48.73  ? 499  TYR A O     1 
ATOM   3910  C CB    . TYR A 1 499  ? 204.887 313.698 252.075 1.00 48.73  ? 499  TYR A CB    1 
ATOM   3911  C CG    . TYR A 1 499  ? 204.096 313.697 250.786 1.00 48.73  ? 499  TYR A CG    1 
ATOM   3912  C CD1   . TYR A 1 499  ? 204.558 313.020 249.666 1.00 48.73  ? 499  TYR A CD1   1 
ATOM   3913  C CD2   . TYR A 1 499  ? 202.882 314.367 250.693 1.00 48.73  ? 499  TYR A CD2   1 
ATOM   3914  C CE1   . TYR A 1 499  ? 203.838 313.015 248.486 1.00 48.73  ? 499  TYR A CE1   1 
ATOM   3915  C CE2   . TYR A 1 499  ? 202.155 314.367 249.518 1.00 48.73  ? 499  TYR A CE2   1 
ATOM   3916  C CZ    . TYR A 1 499  ? 202.637 313.690 248.418 1.00 48.73  ? 499  TYR A CZ    1 
ATOM   3917  O OH    . TYR A 1 499  ? 201.916 313.688 247.246 1.00 48.73  ? 499  TYR A OH    1 
ATOM   3918  N N     . ARG A 1 500  ? 206.006 316.359 250.338 1.00 52.77  ? 500  ARG A N     1 
ATOM   3919  C CA    . ARG A 1 500  ? 205.657 317.629 249.722 1.00 52.77  ? 500  ARG A CA    1 
ATOM   3920  C C     . ARG A 1 500  ? 205.619 317.453 248.212 1.00 52.77  ? 500  ARG A C     1 
ATOM   3921  O O     . ARG A 1 500  ? 206.254 316.549 247.661 1.00 52.77  ? 500  ARG A O     1 
ATOM   3922  C CB    . ARG A 1 500  ? 206.650 318.734 250.102 1.00 52.77  ? 500  ARG A CB    1 
ATOM   3923  C CG    . ARG A 1 500  ? 206.140 319.693 251.166 1.00 52.77  ? 500  ARG A CG    1 
ATOM   3924  C CD    . ARG A 1 500  ? 207.247 320.617 251.648 1.00 52.77  ? 500  ARG A CD    1 
ATOM   3925  N NE    . ARG A 1 500  ? 207.554 320.416 253.059 1.00 52.77  ? 500  ARG A NE    1 
ATOM   3926  C CZ    . ARG A 1 500  ? 208.529 321.036 253.709 1.00 52.77  ? 500  ARG A CZ    1 
ATOM   3927  N NH1   . ARG A 1 500  ? 209.316 321.911 253.104 1.00 52.77  ? 500  ARG A NH1   1 
ATOM   3928  N NH2   . ARG A 1 500  ? 208.720 320.772 254.999 1.00 52.77  ? 500  ARG A NH2   1 
ATOM   3929  N N     . HIS A 1 501  ? 204.868 318.328 247.549 1.00 55.74  ? 501  HIS A N     1 
ATOM   3930  C CA    . HIS A 1 501  ? 204.762 318.276 246.099 1.00 55.74  ? 501  HIS A CA    1 
ATOM   3931  C C     . HIS A 1 501  ? 206.059 318.740 245.445 1.00 55.74  ? 501  HIS A C     1 
ATOM   3932  O O     . HIS A 1 501  ? 206.810 319.545 246.001 1.00 55.74  ? 501  HIS A O     1 
ATOM   3933  C CB    . HIS A 1 501  ? 203.594 319.137 245.617 1.00 55.74  ? 501  HIS A CB    1 
ATOM   3934  C CG    . HIS A 1 501  ? 203.992 320.518 245.201 1.00 55.74  ? 501  HIS A CG    1 
ATOM   3935  N ND1   . HIS A 1 501  ? 204.424 321.472 246.098 1.00 55.74  ? 501  HIS A ND1   1 
ATOM   3936  C CD2   . HIS A 1 501  ? 204.022 321.108 243.982 1.00 55.74  ? 501  HIS A CD2   1 
ATOM   3937  C CE1   . HIS A 1 501  ? 204.703 322.589 245.450 1.00 55.74  ? 501  HIS A CE1   1 
ATOM   3938  N NE2   . HIS A 1 501  ? 204.468 322.395 244.165 1.00 55.74  ? 501  HIS A NE2   1 
ATOM   3939  N N     . MET A 1 502  ? 206.316 318.219 244.250 1.00 47.40  ? 502  MET A N     1 
ATOM   3940  C CA    . MET A 1 502  ? 207.501 318.567 243.479 1.00 47.40  ? 502  MET A CA    1 
ATOM   3941  C C     . MET A 1 502  ? 207.099 319.447 242.303 1.00 47.40  ? 502  MET A C     1 
ATOM   3942  O O     . MET A 1 502  ? 206.164 319.118 241.566 1.00 47.40  ? 502  MET A O     1 
ATOM   3943  C CB    . MET A 1 502  ? 208.219 317.310 242.979 1.00 47.40  ? 502  MET A CB    1 
ATOM   3944  C CG    . MET A 1 502  ? 209.079 316.599 244.026 1.00 47.40  ? 502  MET A CG    1 
ATOM   3945  S SD    . MET A 1 502  ? 210.531 317.464 244.684 1.00 47.40  ? 502  MET A SD    1 
ATOM   3946  C CE    . MET A 1 502  ? 210.913 318.667 243.409 1.00 47.40  ? 502  MET A CE    1 
ATOM   3947  N N     . GLY A 1 503  ? 207.807 320.562 242.131 1.00 43.44  ? 503  GLY A N     1 
ATOM   3948  C CA    . GLY A 1 503  ? 207.505 321.496 241.070 1.00 43.44  ? 503  GLY A CA    1 
ATOM   3949  C C     . GLY A 1 503  ? 208.074 321.068 239.731 1.00 43.44  ? 503  GLY A C     1 
ATOM   3950  O O     . GLY A 1 503  ? 208.657 319.996 239.572 1.00 43.44  ? 503  GLY A O     1 
ATOM   3951  N N     . VAL A 1 504  ? 207.887 321.943 238.740 1.00 43.21  ? 504  VAL A N     1 
ATOM   3952  C CA    . VAL A 1 504  ? 208.383 321.664 237.396 1.00 43.21  ? 504  VAL A CA    1 
ATOM   3953  C C     . VAL A 1 504  ? 209.908 321.654 237.377 1.00 43.21  ? 504  VAL A C     1 
ATOM   3954  O O     . VAL A 1 504  ? 210.528 320.872 236.646 1.00 43.21  ? 504  VAL A O     1 
ATOM   3955  C CB    . VAL A 1 504  ? 207.800 322.675 236.390 1.00 43.21  ? 504  VAL A CB    1 
ATOM   3956  C CG1   . VAL A 1 504  ? 208.213 324.100 236.741 1.00 43.21  ? 504  VAL A CG1   1 
ATOM   3957  C CG2   . VAL A 1 504  ? 208.220 322.323 234.969 1.00 43.21  ? 504  VAL A CG2   1 
ATOM   3958  N N     . LEU A 1 505  ? 210.537 322.511 238.184 1.00 44.70  ? 505  LEU A N     1 
ATOM   3959  C CA    . LEU A 1 505  ? 211.992 322.601 238.194 1.00 44.70  ? 505  LEU A CA    1 
ATOM   3960  C C     . LEU A 1 505  ? 212.648 321.372 238.810 1.00 44.70  ? 505  LEU A C     1 
ATOM   3961  O O     . LEU A 1 505  ? 213.849 321.162 238.611 1.00 44.70  ? 505  LEU A O     1 
ATOM   3962  C CB    . LEU A 1 505  ? 212.430 323.859 238.943 1.00 44.70  ? 505  LEU A CB    1 
ATOM   3963  C CG    . LEU A 1 505  ? 212.393 325.155 238.130 1.00 44.70  ? 505  LEU A CG    1 
ATOM   3964  C CD1   . LEU A 1 505  ? 212.309 326.362 239.046 1.00 44.70  ? 505  LEU A CD1   1 
ATOM   3965  C CD2   . LEU A 1 505  ? 213.607 325.252 237.221 1.00 44.70  ? 505  LEU A CD2   1 
ATOM   3966  N N     . GLY A 1 506  ? 211.895 320.562 239.549 1.00 38.05  ? 506  GLY A N     1 
ATOM   3967  C CA    . GLY A 1 506  ? 212.443 319.367 240.157 1.00 38.05  ? 506  GLY A CA    1 
ATOM   3968  C C     . GLY A 1 506  ? 212.313 318.136 239.284 1.00 38.05  ? 506  GLY A C     1 
ATOM   3969  O O     . GLY A 1 506  ? 213.257 317.351 239.162 1.00 38.05  ? 506  GLY A O     1 
ATOM   3970  N N     . THR A 1 507  ? 211.141 317.954 238.671 1.00 36.40  ? 507  THR A N     1 
ATOM   3971  C CA    . THR A 1 507  ? 210.917 316.790 237.822 1.00 36.40  ? 507  THR A CA    1 
ATOM   3972  C C     . THR A 1 507  ? 211.638 316.895 236.485 1.00 36.40  ? 507  THR A C     1 
ATOM   3973  O O     . THR A 1 507  ? 211.795 315.879 235.800 1.00 36.40  ? 507  THR A O     1 
ATOM   3974  C CB    . THR A 1 507  ? 209.419 316.591 237.583 1.00 36.40  ? 507  THR A CB    1 
ATOM   3975  O OG1   . THR A 1 507  ? 208.879 317.747 236.933 1.00 36.40  ? 507  THR A OG1   1 
ATOM   3976  C CG2   . THR A 1 507  ? 208.694 316.373 238.903 1.00 36.40  ? 507  THR A CG2   1 
ATOM   3977  N N     . SER A 1 508  ? 212.073 318.096 236.096 1.00 36.62  ? 508  SER A N     1 
ATOM   3978  C CA    . SER A 1 508  ? 212.726 318.263 234.801 1.00 36.62  ? 508  SER A CA    1 
ATOM   3979  C C     . SER A 1 508  ? 214.081 317.567 234.763 1.00 36.62  ? 508  SER A C     1 
ATOM   3980  O O     . SER A 1 508  ? 214.407 316.881 233.787 1.00 36.62  ? 508  SER A O     1 
ATOM   3981  C CB    . SER A 1 508  ? 212.876 319.749 234.479 1.00 36.62  ? 508  SER A CB    1 
ATOM   3982  O OG    . SER A 1 508  ? 211.685 320.453 234.781 1.00 36.62  ? 508  SER A OG    1 
ATOM   3983  N N     . LYS A 1 509  ? 214.884 317.733 235.810 1.00 38.54  ? 509  LYS A N     1 
ATOM   3984  C CA    . LYS A 1 509  ? 216.212 317.138 235.833 1.00 38.54  ? 509  LYS A CA    1 
ATOM   3985  C C     . LYS A 1 509  ? 216.124 315.620 235.942 1.00 38.54  ? 509  LYS A C     1 
ATOM   3986  O O     . LYS A 1 509  ? 215.244 315.069 236.609 1.00 38.54  ? 509  LYS A O     1 
ATOM   3987  C CB    . LYS A 1 509  ? 217.032 317.704 236.994 1.00 38.54  ? 509  LYS A CB    1 
ATOM   3988  C CG    . LYS A 1 509  ? 216.358 317.589 238.351 1.00 38.54  ? 509  LYS A CG    1 
ATOM   3989  C CD    . LYS A 1 509  ? 217.373 317.645 239.480 1.00 38.54  ? 509  LYS A CD    1 
ATOM   3990  C CE    . LYS A 1 509  ? 218.154 318.949 239.457 1.00 38.54  ? 509  LYS A CE    1 
ATOM   3991  N NZ    . LYS A 1 509  ? 218.531 319.394 240.827 1.00 38.54  ? 509  LYS A NZ    1 
ATOM   3992  N N     . LEU A 1 510  ? 217.051 314.944 235.270 1.00 42.55  ? 510  LEU A N     1 
ATOM   3993  C CA    . LEU A 1 510  ? 217.097 313.490 235.267 1.00 42.55  ? 510  LEU A CA    1 
ATOM   3994  C C     . LEU A 1 510  ? 217.682 312.970 236.573 1.00 42.55  ? 510  LEU A C     1 
ATOM   3995  O O     . LEU A 1 510  ? 218.523 313.617 237.203 1.00 42.55  ? 510  LEU A O     1 
ATOM   3996  C CB    . LEU A 1 510  ? 217.922 312.977 234.085 1.00 42.55  ? 510  LEU A CB    1 
ATOM   3997  C CG    . LEU A 1 510  ? 217.288 313.115 232.700 1.00 42.55  ? 510  LEU A CG    1 
ATOM   3998  C CD1   . LEU A 1 510  ? 218.336 312.953 231.610 1.00 42.55  ? 510  LEU A CD1   1 
ATOM   3999  C CD2   . LEU A 1 510  ? 216.162 312.108 232.520 1.00 42.55  ? 510  LEU A CD2   1 
ATOM   4000  N N     . TYR A 1 511  ? 217.225 311.787 236.976 1.00 42.51  ? 511  TYR A N     1 
ATOM   4001  C CA    . TYR A 1 511  ? 217.669 311.148 238.206 1.00 42.51  ? 511  TYR A CA    1 
ATOM   4002  C C     . TYR A 1 511  ? 218.196 309.755 237.897 1.00 42.51  ? 511  TYR A C     1 
ATOM   4003  O O     . TYR A 1 511  ? 217.617 309.028 237.085 1.00 42.51  ? 511  TYR A O     1 
ATOM   4004  C CB    . TYR A 1 511  ? 216.531 311.062 239.230 1.00 42.51  ? 511  TYR A CB    1 
ATOM   4005  C CG    . TYR A 1 511  ? 215.958 312.405 239.621 1.00 42.51  ? 511  TYR A CG    1 
ATOM   4006  C CD1   . TYR A 1 511  ? 216.675 313.279 240.428 1.00 42.51  ? 511  TYR A CD1   1 
ATOM   4007  C CD2   . TYR A 1 511  ? 214.702 312.800 239.181 1.00 42.51  ? 511  TYR A CD2   1 
ATOM   4008  C CE1   . TYR A 1 511  ? 216.155 314.507 240.788 1.00 42.51  ? 511  TYR A CE1   1 
ATOM   4009  C CE2   . TYR A 1 511  ? 214.175 314.027 239.535 1.00 42.51  ? 511  TYR A CE2   1 
ATOM   4010  C CZ    . TYR A 1 511  ? 214.905 314.876 240.338 1.00 42.51  ? 511  TYR A CZ    1 
ATOM   4011  O OH    . TYR A 1 511  ? 214.385 316.099 240.694 1.00 42.51  ? 511  TYR A OH    1 
ATOM   4012  N N     . ASP A 1 512  ? 219.297 309.391 238.549 1.00 44.81  ? 512  ASP A N     1 
ATOM   4013  C CA    . ASP A 1 512  ? 219.920 308.084 238.388 1.00 44.81  ? 512  ASP A CA    1 
ATOM   4014  C C     . ASP A 1 512  ? 219.738 307.293 239.676 1.00 44.81  ? 512  ASP A C     1 
ATOM   4015  O O     . ASP A 1 512  ? 220.305 307.652 240.714 1.00 44.81  ? 512  ASP A O     1 
ATOM   4016  C CB    . ASP A 1 512  ? 221.403 308.224 238.042 1.00 44.81  ? 512  ASP A CB    1 
ATOM   4017  C CG    . ASP A 1 512  ? 222.192 306.964 238.337 1.00 44.81  ? 512  ASP A CG    1 
ATOM   4018  O OD1   . ASP A 1 512  ? 222.175 306.039 237.497 1.00 44.81  ? 512  ASP A OD1   1 
ATOM   4019  O OD2   . ASP A 1 512  ? 222.833 306.898 239.407 1.00 44.81  ? 512  ASP A OD2   1 
ATOM   4020  N N     . ILE A 1 513  ? 218.948 306.224 239.608 1.00 47.21  ? 513  ILE A N     1 
ATOM   4021  C CA    . ILE A 1 513  ? 218.671 305.367 240.754 1.00 47.21  ? 513  ILE A CA    1 
ATOM   4022  C C     . ILE A 1 513  ? 219.052 303.940 240.391 1.00 47.21  ? 513  ILE A C     1 
ATOM   4023  O O     . ILE A 1 513  ? 218.574 303.404 239.385 1.00 47.21  ? 513  ILE A O     1 
ATOM   4024  C CB    . ILE A 1 513  ? 217.191 305.435 241.180 1.00 47.21  ? 513  ILE A CB    1 
ATOM   4025  C CG1   . ILE A 1 513  ? 216.690 306.881 241.161 1.00 47.21  ? 513  ILE A CG1   1 
ATOM   4026  C CG2   . ILE A 1 513  ? 217.006 304.817 242.558 1.00 47.21  ? 513  ILE A CG2   1 
ATOM   4027  C CD1   . ILE A 1 513  ? 215.294 307.052 241.722 1.00 47.21  ? 513  ILE A CD1   1 
ATOM   4028  N N     . ARG A 1 514  ? 219.905 303.327 241.215 1.00 51.79  ? 514  ARG A N     1 
ATOM   4029  C CA    . ARG A 1 514  ? 220.338 301.941 241.024 1.00 51.79  ? 514  ARG A CA    1 
ATOM   4030  C C     . ARG A 1 514  ? 220.927 301.729 239.631 1.00 51.79  ? 514  ARG A C     1 
ATOM   4031  O O     . ARG A 1 514  ? 220.610 300.758 238.940 1.00 51.79  ? 514  ARG A O     1 
ATOM   4032  C CB    . ARG A 1 514  ? 219.188 300.967 241.287 1.00 51.79  ? 514  ARG A CB    1 
ATOM   4033  C CG    . ARG A 1 514  ? 218.701 300.963 242.727 1.00 51.79  ? 514  ARG A CG    1 
ATOM   4034  C CD    . ARG A 1 514  ? 218.307 299.564 243.177 1.00 51.79  ? 514  ARG A CD    1 
ATOM   4035  N NE    . ARG A 1 514  ? 217.939 299.526 244.587 1.00 51.79  ? 514  ARG A NE    1 
ATOM   4036  C CZ    . ARG A 1 514  ? 216.787 299.966 245.076 1.00 51.79  ? 514  ARG A CZ    1 
ATOM   4037  N NH1   . ARG A 1 514  ? 215.854 300.481 244.292 1.00 51.79  ? 514  ARG A NH1   1 
ATOM   4038  N NH2   . ARG A 1 514  ? 216.564 299.884 246.385 1.00 51.79  ? 514  ARG A NH2   1 
ATOM   4039  N N     . LYS A 1 515  ? 221.789 302.661 239.216 1.00 53.11  ? 515  LYS A N     1 
ATOM   4040  C CA    . LYS A 1 515  ? 222.451 302.620 237.910 1.00 53.11  ? 515  LYS A CA    1 
ATOM   4041  C C     . LYS A 1 515  ? 221.444 302.616 236.763 1.00 53.11  ? 515  LYS A C     1 
ATOM   4042  O O     . LYS A 1 515  ? 221.699 302.046 235.699 1.00 53.11  ? 515  LYS A O     1 
ATOM   4043  C CB    . LYS A 1 515  ? 223.393 301.417 237.797 1.00 53.11  ? 515  LYS A CB    1 
ATOM   4044  C CG    . LYS A 1 515  ? 224.470 301.368 238.868 1.00 53.11  ? 515  LYS A CG    1 
ATOM   4045  C CD    . LYS A 1 515  ? 225.020 299.960 239.031 1.00 53.11  ? 515  LYS A CD    1 
ATOM   4046  C CE    . LYS A 1 515  ? 224.577 299.343 240.347 1.00 53.11  ? 515  LYS A CE    1 
ATOM   4047  N NZ    . LYS A 1 515  ? 224.878 297.886 240.406 1.00 53.11  ? 515  LYS A NZ    1 
ATOM   4048  N N     . THR A 1 516  ? 220.292 303.250 236.970 1.00 44.56  ? 516  THR A N     1 
ATOM   4049  C CA    . THR A 1 516  ? 219.256 303.354 235.954 1.00 44.56  ? 516  THR A CA    1 
ATOM   4050  C C     . THR A 1 516  ? 218.760 304.791 235.890 1.00 44.56  ? 516  THR A C     1 
ATOM   4051  O O     . THR A 1 516  ? 218.540 305.427 236.925 1.00 44.56  ? 516  THR A O     1 
ATOM   4052  C CB    . THR A 1 516  ? 218.084 302.407 236.248 1.00 44.56  ? 516  THR A CB    1 
ATOM   4053  O OG1   . THR A 1 516  ? 218.587 301.093 236.522 1.00 44.56  ? 516  THR A OG1   1 
ATOM   4054  C CG2   . THR A 1 516  ? 217.139 302.341 235.059 1.00 44.56  ? 516  THR A CG2   1 
ATOM   4055  N N     . ILE A 1 517  ? 218.585 305.296 234.673 1.00 44.25  ? 517  ILE A N     1 
ATOM   4056  C CA    . ILE A 1 517  ? 218.130 306.665 234.459 1.00 44.25  ? 517  ILE A CA    1 
ATOM   4057  C C     . ILE A 1 517  ? 216.616 306.705 234.608 1.00 44.25  ? 517  ILE A C     1 
ATOM   4058  O O     . ILE A 1 517  ? 215.894 305.958 233.936 1.00 44.25  ? 517  ILE A O     1 
ATOM   4059  C CB    . ILE A 1 517  ? 218.565 307.180 233.077 1.00 44.25  ? 517  ILE A CB    1 
ATOM   4060  C CG1   . ILE A 1 517  ? 220.036 307.600 233.102 1.00 44.25  ? 517  ILE A CG1   1 
ATOM   4061  C CG2   . ILE A 1 517  ? 217.693 308.350 232.643 1.00 44.25  ? 517  ILE A CG2   1 
ATOM   4062  C CD1   . ILE A 1 517  ? 220.421 308.423 234.315 1.00 44.25  ? 517  ILE A CD1   1 
ATOM   4063  N N     . PHE A 1 518  ? 216.133 307.572 235.494 1.00 40.00  ? 518  PHE A N     1 
ATOM   4064  C CA    . PHE A 1 518  ? 214.711 307.722 235.764 1.00 40.00  ? 518  PHE A CA    1 
ATOM   4065  C C     . PHE A 1 518  ? 214.268 309.127 235.386 1.00 40.00  ? 518  PHE A C     1 
ATOM   4066  O O     . PHE A 1 518  ? 214.905 310.110 235.779 1.00 40.00  ? 518  PHE A O     1 
ATOM   4067  C CB    . PHE A 1 518  ? 214.396 307.448 237.237 1.00 40.00  ? 518  PHE A CB    1 
ATOM   4068  C CG    . PHE A 1 518  ? 213.807 306.090 237.490 1.00 40.00  ? 518  PHE A CG    1 
ATOM   4069  C CD1   . PHE A 1 518  ? 214.624 304.986 237.669 1.00 40.00  ? 518  PHE A CD1   1 
ATOM   4070  C CD2   . PHE A 1 518  ? 212.434 305.918 237.552 1.00 40.00  ? 518  PHE A CD2   1 
ATOM   4071  C CE1   . PHE A 1 518  ? 214.083 303.736 237.902 1.00 40.00  ? 518  PHE A CE1   1 
ATOM   4072  C CE2   . PHE A 1 518  ? 211.886 304.670 237.785 1.00 40.00  ? 518  PHE A CE2   1 
ATOM   4073  C CZ    . PHE A 1 518  ? 212.712 303.578 237.961 1.00 40.00  ? 518  PHE A CZ    1 
ATOM   4074  N N     . THR A 1 519  ? 213.179 309.216 234.627 1.00 37.23  ? 519  THR A N     1 
ATOM   4075  C CA    . THR A 1 519  ? 212.563 310.486 234.271 1.00 37.23  ? 519  THR A CA    1 
ATOM   4076  C C     . THR A 1 519  ? 211.147 310.510 234.828 1.00 37.23  ? 519  THR A C     1 
ATOM   4077  O O     . THR A 1 519  ? 210.517 309.457 234.978 1.00 37.23  ? 519  THR A O     1 
ATOM   4078  C CB    . THR A 1 519  ? 212.563 310.705 232.750 1.00 37.23  ? 519  THR A CB    1 
ATOM   4079  O OG1   . THR A 1 519  ? 212.520 312.109 232.466 1.00 37.23  ? 519  THR A OG1   1 
ATOM   4080  C CG2   . THR A 1 519  ? 211.374 310.019 232.088 1.00 37.23  ? 519  THR A CG2   1 
ATOM   4081  N N     . PHE A 1 520  ? 210.666 311.700 235.171 1.00 35.69  ? 520  PHE A N     1 
ATOM   4082  C CA    . PHE A 1 520  ? 209.356 311.870 235.782 1.00 35.69  ? 520  PHE A CA    1 
ATOM   4083  C C     . PHE A 1 520  ? 208.544 312.891 234.998 1.00 35.69  ? 520  PHE A C     1 
ATOM   4084  O O     . PHE A 1 520  ? 209.069 313.936 234.600 1.00 35.69  ? 520  PHE A O     1 
ATOM   4085  C CB    . PHE A 1 520  ? 209.487 312.308 237.242 1.00 35.69  ? 520  PHE A CB    1 
ATOM   4086  C CG    . PHE A 1 520  ? 210.149 311.287 238.123 1.00 35.69  ? 520  PHE A CG    1 
ATOM   4087  C CD1   . PHE A 1 520  ? 209.422 310.233 238.651 1.00 35.69  ? 520  PHE A CD1   1 
ATOM   4088  C CD2   . PHE A 1 520  ? 211.498 311.380 238.421 1.00 35.69  ? 520  PHE A CD2   1 
ATOM   4089  C CE1   . PHE A 1 520  ? 210.027 309.292 239.461 1.00 35.69  ? 520  PHE A CE1   1 
ATOM   4090  C CE2   . PHE A 1 520  ? 212.109 310.442 239.231 1.00 35.69  ? 520  PHE A CE2   1 
ATOM   4091  C CZ    . PHE A 1 520  ? 211.373 309.396 239.751 1.00 35.69  ? 520  PHE A CZ    1 
ATOM   4092  N N     . THR A 1 521  ? 207.269 312.582 234.779 1.00 35.54  ? 521  THR A N     1 
ATOM   4093  C CA    . THR A 1 521  ? 206.363 313.529 234.157 1.00 35.54  ? 521  THR A CA    1 
ATOM   4094  C C     . THR A 1 521  ? 206.080 314.685 235.113 1.00 35.54  ? 521  THR A C     1 
ATOM   4095  O O     . THR A 1 521  ? 206.193 314.536 236.333 1.00 35.54  ? 521  THR A O     1 
ATOM   4096  C CB    . THR A 1 521  ? 205.057 312.842 233.766 1.00 35.54  ? 521  THR A CB    1 
ATOM   4097  O OG1   . THR A 1 521  ? 204.415 312.325 234.938 1.00 35.54  ? 521  THR A OG1   1 
ATOM   4098  C CG2   . THR A 1 521  ? 205.322 311.705 232.794 1.00 35.54  ? 521  THR A CG2   1 
ATOM   4099  N N     . PRO A 1 522  ? 205.725 315.854 234.581 1.00 36.02  ? 522  PRO A N     1 
ATOM   4100  C CA    . PRO A 1 522  ? 205.369 316.977 235.456 1.00 36.02  ? 522  PRO A CA    1 
ATOM   4101  C C     . PRO A 1 522  ? 204.168 316.638 236.326 1.00 36.02  ? 522  PRO A C     1 
ATOM   4102  O O     . PRO A 1 522  ? 203.282 315.879 235.929 1.00 36.02  ? 522  PRO A O     1 
ATOM   4103  C CB    . PRO A 1 522  ? 205.055 318.113 234.474 1.00 36.02  ? 522  PRO A CB    1 
ATOM   4104  C CG    . PRO A 1 522  ? 204.919 317.467 233.130 1.00 36.02  ? 522  PRO A CG    1 
ATOM   4105  C CD    . PRO A 1 522  ? 205.774 316.249 233.165 1.00 36.02  ? 522  PRO A CD    1 
ATOM   4106  N N     . GLN A 1 523  ? 204.153 317.207 237.532 1.00 44.12  ? 523  GLN A N     1 
ATOM   4107  C CA    . GLN A 1 523  ? 203.127 316.868 238.511 1.00 44.12  ? 523  GLN A CA    1 
ATOM   4108  C C     . GLN A 1 523  ? 201.752 317.410 238.134 1.00 44.12  ? 523  GLN A C     1 
ATOM   4109  O O     . GLN A 1 523  ? 200.744 316.916 238.651 1.00 44.12  ? 523  GLN A O     1 
ATOM   4110  C CB    . GLN A 1 523  ? 203.544 317.390 239.890 1.00 44.12  ? 523  GLN A CB    1 
ATOM   4111  C CG    . GLN A 1 523  ? 202.677 316.918 241.049 1.00 44.12  ? 523  GLN A CG    1 
ATOM   4112  C CD    . GLN A 1 523  ? 201.622 317.935 241.440 1.00 44.12  ? 523  GLN A CD    1 
ATOM   4113  O OE1   . GLN A 1 523  ? 201.861 319.142 241.395 1.00 44.12  ? 523  GLN A OE1   1 
ATOM   4114  N NE2   . GLN A 1 523  ? 200.448 317.451 241.826 1.00 44.12  ? 523  GLN A NE2   1 
ATOM   4115  N N     . PHE A 1 524  ? 201.678 318.386 237.232 1.00 44.06  ? 524  PHE A N     1 
ATOM   4116  C CA    . PHE A 1 524  ? 200.420 319.068 236.956 1.00 44.06  ? 524  PHE A CA    1 
ATOM   4117  C C     . PHE A 1 524  ? 199.553 318.354 235.925 1.00 44.06  ? 524  PHE A C     1 
ATOM   4118  O O     . PHE A 1 524  ? 198.463 318.846 235.614 1.00 44.06  ? 524  PHE A O     1 
ATOM   4119  C CB    . PHE A 1 524  ? 200.687 320.516 236.514 1.00 44.06  ? 524  PHE A CB    1 
ATOM   4120  C CG    . PHE A 1 524  ? 201.338 320.648 235.159 1.00 44.06  ? 524  PHE A CG    1 
ATOM   4121  C CD1   . PHE A 1 524  ? 200.578 320.635 233.998 1.00 44.06  ? 524  PHE A CD1   1 
ATOM   4122  C CD2   . PHE A 1 524  ? 202.708 320.819 235.049 1.00 44.06  ? 524  PHE A CD2   1 
ATOM   4123  C CE1   . PHE A 1 524  ? 201.173 320.768 232.758 1.00 44.06  ? 524  PHE A CE1   1 
ATOM   4124  C CE2   . PHE A 1 524  ? 203.307 320.956 233.809 1.00 44.06  ? 524  PHE A CE2   1 
ATOM   4125  C CZ    . PHE A 1 524  ? 202.539 320.927 232.664 1.00 44.06  ? 524  PHE A CZ    1 
ATOM   4126  N N     . ILE A 1 525  ? 199.995 317.220 235.390 1.00 48.02  ? 525  ILE A N     1 
ATOM   4127  C CA    . ILE A 1 525  ? 199.204 316.463 234.428 1.00 48.02  ? 525  ILE A CA    1 
ATOM   4128  C C     . ILE A 1 525  ? 198.551 315.240 235.076 1.00 48.02  ? 525  ILE A C     1 
ATOM   4129  O O     . ILE A 1 525  ? 198.158 314.306 234.378 1.00 48.02  ? 525  ILE A O     1 
ATOM   4130  C CB    . ILE A 1 525  ? 200.037 316.060 233.201 1.00 48.02  ? 525  ILE A CB    1 
ATOM   4131  C CG1   . ILE A 1 525  ? 201.240 315.215 233.622 1.00 48.02  ? 525  ILE A CG1   1 
ATOM   4132  C CG2   . ILE A 1 525  ? 200.487 317.292 232.433 1.00 48.02  ? 525  ILE A CG2   1 
ATOM   4133  C CD1   . ILE A 1 525  ? 201.495 314.026 232.722 1.00 48.02  ? 525  ILE A CD1   1 
ATOM   4134  N N     . ASP A 1 526  ? 198.429 315.231 236.402 1.00 58.79  ? 526  ASP A N     1 
ATOM   4135  C CA    . ASP A 1 526  ? 197.832 314.112 237.123 1.00 58.79  ? 526  ASP A CA    1 
ATOM   4136  C C     . ASP A 1 526  ? 196.334 314.361 237.265 1.00 58.79  ? 526  ASP A C     1 
ATOM   4137  O O     . ASP A 1 526  ? 195.912 315.229 238.036 1.00 58.79  ? 526  ASP A O     1 
ATOM   4138  C CB    . ASP A 1 526  ? 198.494 313.937 238.488 1.00 58.79  ? 526  ASP A CB    1 
ATOM   4139  C CG    . ASP A 1 526  ? 198.298 312.545 239.057 1.00 58.79  ? 526  ASP A CG    1 
ATOM   4140  O OD1   . ASP A 1 526  ? 197.500 311.772 238.486 1.00 58.79  ? 526  ASP A OD1   1 
ATOM   4141  O OD2   . ASP A 1 526  ? 198.942 312.223 240.077 1.00 58.79  ? 526  ASP A OD2   1 
ATOM   4142  N N     . GLN A 1 527  ? 195.531 313.599 236.520 1.00 65.92  ? 527  GLN A N     1 
ATOM   4143  C CA    . GLN A 1 527  ? 194.082 313.745 236.593 1.00 65.92  ? 527  GLN A CA    1 
ATOM   4144  C C     . GLN A 1 527  ? 193.506 313.139 237.866 1.00 65.92  ? 527  GLN A C     1 
ATOM   4145  O O     . GLN A 1 527  ? 192.424 313.544 238.304 1.00 65.92  ? 527  GLN A O     1 
ATOM   4146  C CB    . GLN A 1 527  ? 193.426 313.107 235.367 1.00 65.92  ? 527  GLN A CB    1 
ATOM   4147  C CG    . GLN A 1 527  ? 193.946 313.632 234.039 1.00 65.92  ? 527  GLN A CG    1 
ATOM   4148  C CD    . GLN A 1 527  ? 194.341 312.521 233.088 1.00 65.92  ? 527  GLN A CD    1 
ATOM   4149  O OE1   . GLN A 1 527  ? 195.023 311.571 233.473 1.00 65.92  ? 527  GLN A OE1   1 
ATOM   4150  N NE2   . GLN A 1 527  ? 193.912 312.633 231.836 1.00 65.92  ? 527  GLN A NE2   1 
ATOM   4151  N N     . GLN A 1 528  ? 194.198 312.164 238.460 1.00 69.57  ? 528  GLN A N     1 
ATOM   4152  C CA    . GLN A 1 528  ? 193.699 311.542 239.682 1.00 69.57  ? 528  GLN A CA    1 
ATOM   4153  C C     . GLN A 1 528  ? 193.675 312.531 240.841 1.00 69.57  ? 528  GLN A C     1 
ATOM   4154  O O     . GLN A 1 528  ? 192.730 312.540 241.639 1.00 69.57  ? 528  GLN A O     1 
ATOM   4155  C CB    . GLN A 1 528  ? 194.551 310.322 240.035 1.00 69.57  ? 528  GLN A CB    1 
ATOM   4156  C CG    . GLN A 1 528  ? 193.965 309.000 239.566 1.00 69.57  ? 528  GLN A CG    1 
ATOM   4157  C CD    . GLN A 1 528  ? 192.486 308.876 239.875 1.00 69.57  ? 528  GLN A CD    1 
ATOM   4158  O OE1   . GLN A 1 528  ? 192.077 308.917 241.035 1.00 69.57  ? 528  GLN A OE1   1 
ATOM   4159  N NE2   . GLN A 1 528  ? 191.675 308.724 238.835 1.00 69.57  ? 528  GLN A NE2   1 
ATOM   4160  N N     . GLN A 1 529  ? 194.710 313.368 240.954 1.00 76.09  ? 529  GLN A N     1 
ATOM   4161  C CA    . GLN A 1 529  ? 194.783 314.310 242.067 1.00 76.09  ? 529  GLN A CA    1 
ATOM   4162  C C     . GLN A 1 529  ? 193.659 315.338 242.003 1.00 76.09  ? 529  GLN A C     1 
ATOM   4163  O O     . GLN A 1 529  ? 193.035 315.650 243.024 1.00 76.09  ? 529  GLN A O     1 
ATOM   4164  C CB    . GLN A 1 529  ? 196.146 315.004 242.077 1.00 76.09  ? 529  GLN A CB    1 
ATOM   4165  C CG    . GLN A 1 529  ? 196.279 316.110 243.114 1.00 76.09  ? 529  GLN A CG    1 
ATOM   4166  C CD    . GLN A 1 529  ? 195.862 315.667 244.504 1.00 76.09  ? 529  GLN A CD    1 
ATOM   4167  O OE1   . GLN A 1 529  ? 195.065 316.330 245.166 1.00 76.09  ? 529  GLN A OE1   1 
ATOM   4168  N NE2   . GLN A 1 529  ? 196.408 314.543 244.956 1.00 76.09  ? 529  GLN A NE2   1 
ATOM   4169  N N     . PHE A 1 530  ? 193.383 315.872 240.815 1.00 68.36  ? 530  PHE A N     1 
ATOM   4170  C CA    . PHE A 1 530  ? 192.347 316.883 240.661 1.00 68.36  ? 530  PHE A CA    1 
ATOM   4171  C C     . PHE A 1 530  ? 191.856 316.871 239.221 1.00 68.36  ? 530  PHE A C     1 
ATOM   4172  O O     . PHE A 1 530  ? 192.515 316.340 238.324 1.00 68.36  ? 530  PHE A O     1 
ATOM   4173  C CB    . PHE A 1 530  ? 192.857 318.275 241.049 1.00 68.36  ? 530  PHE A CB    1 
ATOM   4174  C CG    . PHE A 1 530  ? 191.967 318.999 242.019 1.00 68.36  ? 530  PHE A CG    1 
ATOM   4175  C CD1   . PHE A 1 530  ? 191.969 318.664 243.363 1.00 68.36  ? 530  PHE A CD1   1 
ATOM   4176  C CD2   . PHE A 1 530  ? 191.128 320.013 241.587 1.00 68.36  ? 530  PHE A CD2   1 
ATOM   4177  C CE1   . PHE A 1 530  ? 191.151 319.327 244.259 1.00 68.36  ? 530  PHE A CE1   1 
ATOM   4178  C CE2   . PHE A 1 530  ? 190.308 320.680 242.478 1.00 68.36  ? 530  PHE A CE2   1 
ATOM   4179  C CZ    . PHE A 1 530  ? 190.319 320.336 243.815 1.00 68.36  ? 530  PHE A CZ    1 
ATOM   4180  N N     . TYR A 1 531  ? 190.690 317.477 239.013 1.00 64.21  ? 531  TYR A N     1 
ATOM   4181  C CA    . TYR A 1 531  ? 190.047 317.510 237.707 1.00 64.21  ? 531  TYR A CA    1 
ATOM   4182  C C     . TYR A 1 531  ? 190.541 318.653 236.828 1.00 64.21  ? 531  TYR A C     1 
ATOM   4183  O O     . TYR A 1 531  ? 190.041 318.813 235.709 1.00 64.21  ? 531  TYR A O     1 
ATOM   4184  C CB    . TYR A 1 531  ? 188.525 317.604 237.869 1.00 64.21  ? 531  TYR A CB    1 
ATOM   4185  C CG    . TYR A 1 531  ? 188.053 318.824 238.631 1.00 64.21  ? 531  TYR A CG    1 
ATOM   4186  C CD1   . TYR A 1 531  ? 187.812 320.025 237.976 1.00 64.21  ? 531  TYR A CD1   1 
ATOM   4187  C CD2   . TYR A 1 531  ? 187.846 318.773 240.003 1.00 64.21  ? 531  TYR A CD2   1 
ATOM   4188  C CE1   . TYR A 1 531  ? 187.381 321.140 238.666 1.00 64.21  ? 531  TYR A CE1   1 
ATOM   4189  C CE2   . TYR A 1 531  ? 187.414 319.885 240.702 1.00 64.21  ? 531  TYR A CE2   1 
ATOM   4190  C CZ    . TYR A 1 531  ? 187.184 321.066 240.028 1.00 64.21  ? 531  TYR A CZ    1 
ATOM   4191  O OH    . TYR A 1 531  ? 186.754 322.176 240.716 1.00 64.21  ? 531  TYR A OH    1 
ATOM   4192  N N     . LEU A 1 532  ? 191.496 319.453 237.308 1.00 58.06  ? 532  LEU A N     1 
ATOM   4193  C CA    . LEU A 1 532  ? 192.006 320.563 236.509 1.00 58.06  ? 532  LEU A CA    1 
ATOM   4194  C C     . LEU A 1 532  ? 192.683 320.066 235.237 1.00 58.06  ? 532  LEU A C     1 
ATOM   4195  O O     . LEU A 1 532  ? 192.619 320.724 234.193 1.00 58.06  ? 532  LEU A O     1 
ATOM   4196  C CB    . LEU A 1 532  ? 192.977 321.404 237.339 1.00 58.06  ? 532  LEU A CB    1 
ATOM   4197  C CG    . LEU A 1 532  ? 192.459 322.758 237.828 1.00 58.06  ? 532  LEU A CG    1 
ATOM   4198  C CD1   . LEU A 1 532  ? 191.257 322.576 238.741 1.00 58.06  ? 532  LEU A CD1   1 
ATOM   4199  C CD2   . LEU A 1 532  ? 193.563 323.530 238.536 1.00 58.06  ? 532  LEU A CD2   1 
ATOM   4200  N N     . ALA A 1 533  ? 193.337 318.905 235.306 1.00 58.34  ? 533  ALA A N     1 
ATOM   4201  C CA    . ALA A 1 533  ? 194.026 318.351 234.147 1.00 58.34  ? 533  ALA A CA    1 
ATOM   4202  C C     . ALA A 1 533  ? 193.073 317.837 233.075 1.00 58.34  ? 533  ALA A C     1 
ATOM   4203  O O     . ALA A 1 533  ? 193.526 317.539 231.965 1.00 58.34  ? 533  ALA A O     1 
ATOM   4204  C CB    . ALA A 1 533  ? 194.964 317.224 234.585 1.00 58.34  ? 533  ALA A CB    1 
ATOM   4205  N N     . LEU A 1 534  ? 191.779 317.712 233.378 1.00 66.13  ? 534  LEU A N     1 
ATOM   4206  C CA    . LEU A 1 534  ? 190.834 317.219 232.381 1.00 66.13  ? 534  LEU A CA    1 
ATOM   4207  C C     . LEU A 1 534  ? 190.683 318.198 231.222 1.00 66.13  ? 534  LEU A C     1 
ATOM   4208  O O     . LEU A 1 534  ? 190.630 317.787 230.057 1.00 66.13  ? 534  LEU A O     1 
ATOM   4209  C CB    . LEU A 1 534  ? 189.479 316.944 233.032 1.00 66.13  ? 534  LEU A CB    1 
ATOM   4210  C CG    . LEU A 1 534  ? 189.447 315.834 234.085 1.00 66.13  ? 534  LEU A CG    1 
ATOM   4211  C CD1   . LEU A 1 534  ? 188.066 315.730 234.714 1.00 66.13  ? 534  LEU A CD1   1 
ATOM   4212  C CD2   . LEU A 1 534  ? 189.865 314.504 233.477 1.00 66.13  ? 534  LEU A CD2   1 
ATOM   4213  N N     . ASP A 1 535  ? 190.609 319.493 231.519 1.00 64.66  ? 535  ASP A N     1 
ATOM   4214  C CA    . ASP A 1 535  ? 190.391 320.487 230.477 1.00 64.66  ? 535  ASP A CA    1 
ATOM   4215  C C     . ASP A 1 535  ? 191.653 320.680 229.645 1.00 64.66  ? 535  ASP A C     1 
ATOM   4216  O O     . ASP A 1 535  ? 192.743 320.899 230.180 1.00 64.66  ? 535  ASP A O     1 
ATOM   4217  C CB    . ASP A 1 535  ? 189.958 321.815 231.097 1.00 64.66  ? 535  ASP A CB    1 
ATOM   4218  C CG    . ASP A 1 535  ? 189.368 322.771 230.078 1.00 64.66  ? 535  ASP A CG    1 
ATOM   4219  O OD1   . ASP A 1 535  ? 190.123 323.269 229.218 1.00 64.66  ? 535  ASP A OD1   1 
ATOM   4220  O OD2   . ASP A 1 535  ? 188.146 323.023 230.137 1.00 64.66  ? 535  ASP A OD2   1 
ATOM   4221  N N     . ASN A 1 536  ? 191.495 320.609 228.320 1.00 62.40  ? 536  ASN A N     1 
ATOM   4222  C CA    . ASN A 1 536  ? 192.643 320.720 227.425 1.00 62.40  ? 536  ASN A CA    1 
ATOM   4223  C C     . ASN A 1 536  ? 193.212 322.134 227.413 1.00 62.40  ? 536  ASN A C     1 
ATOM   4224  O O     . ASN A 1 536  ? 194.434 322.318 227.342 1.00 62.40  ? 536  ASN A O     1 
ATOM   4225  C CB    . ASN A 1 536  ? 192.246 320.290 226.013 1.00 62.40  ? 536  ASN A CB    1 
ATOM   4226  C CG    . ASN A 1 536  ? 191.735 318.863 225.960 1.00 62.40  ? 536  ASN A CG    1 
ATOM   4227  O OD1   . ASN A 1 536  ? 190.629 318.605 225.484 1.00 62.40  ? 536  ASN A OD1   1 
ATOM   4228  N ND2   . ASN A 1 536  ? 192.539 317.928 226.452 1.00 62.40  ? 536  ASN A ND2   1 
ATOM   4229  N N     . LYS A 1 537  ? 192.341 323.146 227.464 1.00 62.41  ? 537  LYS A N     1 
ATOM   4230  C CA    . LYS A 1 537  ? 192.814 324.526 227.483 1.00 62.41  ? 537  LYS A CA    1 
ATOM   4231  C C     . LYS A 1 537  ? 193.642 324.803 228.730 1.00 62.41  ? 537  LYS A C     1 
ATOM   4232  O O     . LYS A 1 537  ? 194.680 325.474 228.661 1.00 62.41  ? 537  LYS A O     1 
ATOM   4233  C CB    . LYS A 1 537  ? 191.630 325.489 227.392 1.00 62.41  ? 537  LYS A CB    1 
ATOM   4234  C CG    . LYS A 1 537  ? 190.784 325.307 226.142 1.00 62.41  ? 537  LYS A CG    1 
ATOM   4235  C CD    . LYS A 1 537  ? 189.464 326.051 226.250 1.00 62.41  ? 537  LYS A CD    1 
ATOM   4236  C CE    . LYS A 1 537  ? 189.602 327.490 225.780 1.00 62.41  ? 537  LYS A CE    1 
ATOM   4237  N NZ    . LYS A 1 537  ? 189.540 327.594 224.295 1.00 62.41  ? 537  LYS A NZ    1 
ATOM   4238  N N     . MET A 1 538  ? 193.203 324.290 229.882 1.00 57.30  ? 538  MET A N     1 
ATOM   4239  C CA    . MET A 1 538  ? 194.021 324.391 231.085 1.00 57.30  ? 538  MET A CA    1 
ATOM   4240  C C     . MET A 1 538  ? 195.349 323.671 230.910 1.00 57.30  ? 538  MET A C     1 
ATOM   4241  O O     . MET A 1 538  ? 196.389 324.171 231.348 1.00 57.30  ? 538  MET A O     1 
ATOM   4242  C CB    . MET A 1 538  ? 193.268 323.842 232.296 1.00 57.30  ? 538  MET A CB    1 
ATOM   4243  C CG    . MET A 1 538  ? 193.509 324.641 233.569 1.00 57.30  ? 538  MET A CG    1 
ATOM   4244  S SD    . MET A 1 538  ? 192.898 326.332 233.486 1.00 57.30  ? 538  MET A SD    1 
ATOM   4245  C CE    . MET A 1 538  ? 191.139 326.040 233.434 1.00 57.30  ? 538  MET A CE    1 
ATOM   4246  N N     . ILE A 1 539  ? 195.338 322.502 230.265 1.00 52.65  ? 539  ILE A N     1 
ATOM   4247  C CA    . ILE A 1 539  ? 196.582 321.766 230.048 1.00 52.65  ? 539  ILE A CA    1 
ATOM   4248  C C     . ILE A 1 539  ? 197.570 322.608 229.251 1.00 52.65  ? 539  ILE A C     1 
ATOM   4249  O O     . ILE A 1 539  ? 198.730 322.769 229.647 1.00 52.65  ? 539  ILE A O     1 
ATOM   4250  C CB    . ILE A 1 539  ? 196.304 320.419 229.357 1.00 52.65  ? 539  ILE A CB    1 
ATOM   4251  C CG1   . ILE A 1 539  ? 195.535 319.487 230.293 1.00 52.65  ? 539  ILE A CG1   1 
ATOM   4252  C CG2   . ILE A 1 539  ? 197.605 319.775 228.896 1.00 52.65  ? 539  ILE A CG2   1 
ATOM   4253  C CD1   . ILE A 1 539  ? 196.398 318.872 231.374 1.00 52.65  ? 539  ILE A CD1   1 
ATOM   4254  N N     . VAL A 1 540  ? 197.121 323.179 228.131 1.00 54.46  ? 540  VAL A N     1 
ATOM   4255  C CA    . VAL A 1 540  ? 198.050 323.912 227.274 1.00 54.46  ? 540  VAL A CA    1 
ATOM   4256  C C     . VAL A 1 540  ? 198.495 325.213 227.939 1.00 54.46  ? 540  VAL A C     1 
ATOM   4257  O O     . VAL A 1 540  ? 199.678 325.575 227.885 1.00 54.46  ? 540  VAL A O     1 
ATOM   4258  C CB    . VAL A 1 540  ? 197.439 324.150 225.878 1.00 54.46  ? 540  VAL A CB    1 
ATOM   4259  C CG1   . VAL A 1 540  ? 197.227 322.823 225.164 1.00 54.46  ? 540  VAL A CG1   1 
ATOM   4260  C CG2   . VAL A 1 540  ? 196.133 324.917 225.965 1.00 54.46  ? 540  VAL A CG2   1 
ATOM   4261  N N     . GLU A 1 541  ? 197.572 325.927 228.594 1.00 57.56  ? 541  GLU A N     1 
ATOM   4262  C CA    . GLU A 1 541  ? 197.944 327.172 229.259 1.00 57.56  ? 541  GLU A CA    1 
ATOM   4263  C C     . GLU A 1 541  ? 198.926 326.921 230.397 1.00 57.56  ? 541  GLU A C     1 
ATOM   4264  O O     . GLU A 1 541  ? 199.913 327.653 230.552 1.00 57.56  ? 541  GLU A O     1 
ATOM   4265  C CB    . GLU A 1 541  ? 196.693 327.883 229.776 1.00 57.56  ? 541  GLU A CB    1 
ATOM   4266  C CG    . GLU A 1 541  ? 196.977 329.040 230.720 1.00 57.56  ? 541  GLU A CG    1 
ATOM   4267  C CD    . GLU A 1 541  ? 195.833 330.033 230.787 1.00 57.56  ? 541  GLU A CD    1 
ATOM   4268  O OE1   . GLU A 1 541  ? 194.690 329.647 230.464 1.00 57.56  ? 541  GLU A OE1   1 
ATOM   4269  O OE2   . GLU A 1 541  ? 196.077 331.199 231.162 1.00 57.56  ? 541  GLU A OE2   1 
ATOM   4270  N N     . MET A 1 542  ? 198.682 325.881 231.197 1.00 51.40  ? 542  MET A N     1 
ATOM   4271  C CA    . MET A 1 542  ? 199.557 325.583 232.322 1.00 51.40  ? 542  MET A CA    1 
ATOM   4272  C C     . MET A 1 542  ? 200.903 325.055 231.846 1.00 51.40  ? 542  MET A C     1 
ATOM   4273  O O     . MET A 1 542  ? 201.936 325.335 232.463 1.00 51.40  ? 542  MET A O     1 
ATOM   4274  C CB    . MET A 1 542  ? 198.862 324.590 233.252 1.00 51.40  ? 542  MET A CB    1 
ATOM   4275  C CG    . MET A 1 542  ? 198.197 325.255 234.446 1.00 51.40  ? 542  MET A CG    1 
ATOM   4276  S SD    . MET A 1 542  ? 197.122 324.168 235.402 1.00 51.40  ? 542  MET A SD    1 
ATOM   4277  C CE    . MET A 1 542  ? 198.109 322.682 235.475 1.00 51.40  ? 542  MET A CE    1 
ATOM   4278  N N     . LEU A 1 543  ? 200.918 324.304 230.740 1.00 46.12  ? 543  LEU A N     1 
ATOM   4279  C CA    . LEU A 1 543  ? 202.185 323.884 230.153 1.00 46.12  ? 543  LEU A CA    1 
ATOM   4280  C C     . LEU A 1 543  ? 202.993 325.084 229.678 1.00 46.12  ? 543  LEU A C     1 
ATOM   4281  O O     . LEU A 1 543  ? 204.208 325.148 229.896 1.00 46.12  ? 543  LEU A O     1 
ATOM   4282  C CB    . LEU A 1 543  ? 201.932 322.913 228.999 1.00 46.12  ? 543  LEU A CB    1 
ATOM   4283  C CG    . LEU A 1 543  ? 203.128 322.564 228.109 1.00 46.12  ? 543  LEU A CG    1 
ATOM   4284  C CD1   . LEU A 1 543  ? 204.244 321.927 228.925 1.00 46.12  ? 543  LEU A CD1   1 
ATOM   4285  C CD2   . LEU A 1 543  ? 202.702 321.651 226.970 1.00 46.12  ? 543  LEU A CD2   1 
ATOM   4286  N N     . ARG A 1 544  ? 202.334 326.051 229.032 1.00 48.96  ? 544  ARG A N     1 
ATOM   4287  C CA    . ARG A 1 544  ? 203.041 327.248 228.587 1.00 48.96  ? 544  ARG A CA    1 
ATOM   4288  C C     . ARG A 1 544  ? 203.568 328.048 229.775 1.00 48.96  ? 544  ARG A C     1 
ATOM   4289  O O     . ARG A 1 544  ? 204.696 328.556 229.741 1.00 48.96  ? 544  ARG A O     1 
ATOM   4290  C CB    . ARG A 1 544  ? 202.127 328.098 227.696 1.00 48.96  ? 544  ARG A CB    1 
ATOM   4291  C CG    . ARG A 1 544  ? 201.652 329.416 228.296 1.00 48.96  ? 544  ARG A CG    1 
ATOM   4292  C CD    . ARG A 1 544  ? 200.514 330.021 227.489 1.00 48.96  ? 544  ARG A CD    1 
ATOM   4293  N NE    . ARG A 1 544  ? 200.787 330.015 226.057 1.00 48.96  ? 544  ARG A NE    1 
ATOM   4294  C CZ    . ARG A 1 544  ? 199.877 330.250 225.122 1.00 48.96  ? 544  ARG A CZ    1 
ATOM   4295  N NH1   . ARG A 1 544  ? 198.618 330.515 225.433 1.00 48.96  ? 544  ARG A NH1   1 
ATOM   4296  N NH2   . ARG A 1 544  ? 200.238 330.219 223.842 1.00 48.96  ? 544  ARG A NH2   1 
ATOM   4297  N N     . THR A 1 545  ? 202.774 328.149 230.847 1.00 54.46  ? 545  THR A N     1 
ATOM   4298  C CA    . THR A 1 545  ? 203.224 328.869 232.035 1.00 54.46  ? 545  THR A CA    1 
ATOM   4299  C C     . THR A 1 545  ? 204.415 328.173 232.682 1.00 54.46  ? 545  THR A C     1 
ATOM   4300  O O     . THR A 1 545  ? 205.381 328.828 233.094 1.00 54.46  ? 545  THR A O     1 
ATOM   4301  C CB    . THR A 1 545  ? 202.075 329.005 233.035 1.00 54.46  ? 545  THR A CB    1 
ATOM   4302  O OG1   . THR A 1 545  ? 200.927 329.551 232.375 1.00 54.46  ? 545  THR A OG1   1 
ATOM   4303  C CG2   . THR A 1 545  ? 202.474 329.918 234.185 1.00 54.46  ? 545  THR A CG2   1 
ATOM   4304  N N     . ASP A 1 546  ? 204.366 326.842 232.776 1.00 52.50  ? 546  ASP A N     1 
ATOM   4305  C CA    . ASP A 1 546  ? 205.475 326.092 233.355 1.00 52.50  ? 546  ASP A CA    1 
ATOM   4306  C C     . ASP A 1 546  ? 206.729 326.221 232.502 1.00 52.50  ? 546  ASP A C     1 
ATOM   4307  O O     . ASP A 1 546  ? 207.840 326.328 233.031 1.00 52.50  ? 546  ASP A O     1 
ATOM   4308  C CB    . ASP A 1 546  ? 205.079 324.626 233.522 1.00 52.50  ? 546  ASP A CB    1 
ATOM   4309  C CG    . ASP A 1 546  ? 204.539 324.322 234.905 1.00 52.50  ? 546  ASP A CG    1 
ATOM   4310  O OD1   . ASP A 1 546  ? 203.846 325.191 235.477 1.00 52.50  ? 546  ASP A OD1   1 
ATOM   4311  O OD2   . ASP A 1 546  ? 204.799 323.215 235.419 1.00 52.50  ? 546  ASP A OD2   1 
ATOM   4312  N N     . LEU A 1 547  ? 206.572 326.213 231.181 1.00 48.13  ? 547  LEU A N     1 
ATOM   4313  C CA    . LEU A 1 547  ? 207.696 326.388 230.271 1.00 48.13  ? 547  LEU A CA    1 
ATOM   4314  C C     . LEU A 1 547  ? 208.327 327.765 230.450 1.00 48.13  ? 547  LEU A C     1 
ATOM   4315  O O     . LEU A 1 547  ? 209.550 327.896 230.469 1.00 48.13  ? 547  LEU A O     1 
ATOM   4316  C CB    . LEU A 1 547  ? 207.248 326.196 228.821 1.00 48.13  ? 547  LEU A CB    1 
ATOM   4317  C CG    . LEU A 1 547  ? 207.414 324.789 228.243 1.00 48.13  ? 547  LEU A CG    1 
ATOM   4318  C CD1   . LEU A 1 547  ? 206.488 324.583 227.056 1.00 48.13  ? 547  LEU A CD1   1 
ATOM   4319  C CD2   . LEU A 1 547  ? 208.860 324.540 227.846 1.00 48.13  ? 547  LEU A CD2   1 
HETATM 4320  N N     . SEP A 1 548  ? 207.485 328.785 230.588 1.00 67.31  ? 548  SEP A N     1 
HETATM 4321  C CA    . SEP A 1 548  ? 207.965 330.145 230.813 1.00 67.31  ? 548  SEP A CA    1 
HETATM 4322  C CB    . SEP A 1 548  ? 206.797 331.133 230.805 1.00 67.31  ? 548  SEP A CB    1 
HETATM 4323  O OG    . SEP A 1 548  ? 207.255 332.470 230.898 1.00 67.31  ? 548  SEP A OG    1 
HETATM 4324  C C     . SEP A 1 548  ? 208.733 330.246 232.130 1.00 67.31  ? 548  SEP A C     1 
HETATM 4325  O O     . SEP A 1 548  ? 209.800 330.862 232.195 1.00 67.31  ? 548  SEP A O     1 
HETATM 4326  P P     . SEP A 1 548  ? 206.010 333.485 230.787 1.00 67.31  ? 548  SEP A P     1 
HETATM 4327  O O1P   . SEP A 1 548  ? 206.550 334.970 230.481 1.00 67.31  ? 548  SEP A O1P   1 
HETATM 4328  O O2P   . SEP A 1 548  ? 205.039 333.012 229.592 1.00 67.31  ? 548  SEP A O2P   1 
HETATM 4329  O O3P   . SEP A 1 548  ? 205.190 333.484 232.172 1.00 67.31  ? 548  SEP A O3P   1 
ATOM   4330  N N     . TYR A 1 549  ? 208.182 329.630 233.173 1.00 57.68  ? 549  TYR A N     1 
ATOM   4331  C CA    . TYR A 1 549  ? 208.811 329.615 234.491 1.00 57.68  ? 549  TYR A CA    1 
ATOM   4332  C C     . TYR A 1 549  ? 210.183 328.945 234.401 1.00 57.68  ? 549  TYR A C     1 
ATOM   4333  O O     . TYR A 1 549  ? 211.176 329.467 234.909 1.00 57.68  ? 549  TYR A O     1 
ATOM   4334  C CB    . TYR A 1 549  ? 207.917 328.882 235.499 1.00 57.68  ? 549  TYR A CB    1 
ATOM   4335  C CG    . TYR A 1 549  ? 208.400 328.898 236.939 1.00 57.68  ? 549  TYR A CG    1 
ATOM   4336  C CD1   . TYR A 1 549  ? 209.408 329.760 237.355 1.00 57.68  ? 549  TYR A CD1   1 
ATOM   4337  C CD2   . TYR A 1 549  ? 207.810 328.077 237.892 1.00 57.68  ? 549  TYR A CD2   1 
ATOM   4338  C CE1   . TYR A 1 549  ? 209.839 329.777 238.668 1.00 57.68  ? 549  TYR A CE1   1 
ATOM   4339  C CE2   . TYR A 1 549  ? 208.234 328.088 239.208 1.00 57.68  ? 549  TYR A CE2   1 
ATOM   4340  C CZ    . TYR A 1 549  ? 209.247 328.941 239.590 1.00 57.68  ? 549  TYR A CZ    1 
ATOM   4341  O OH    . TYR A 1 549  ? 209.670 328.958 240.900 1.00 57.68  ? 549  TYR A OH    1 
ATOM   4342  N N     . LEU A 1 550  ? 210.225 327.785 233.741 1.00 47.49  ? 550  LEU A N     1 
ATOM   4343  C CA    . LEU A 1 550  ? 211.477 327.048 233.604 1.00 47.49  ? 550  LEU A CA    1 
ATOM   4344  C C     . LEU A 1 550  ? 212.510 327.851 232.823 1.00 47.49  ? 550  LEU A C     1 
ATOM   4345  O O     . LEU A 1 550  ? 213.689 327.885 233.192 1.00 47.49  ? 550  LEU A O     1 
ATOM   4346  C CB    . LEU A 1 550  ? 211.214 325.705 232.924 1.00 47.49  ? 550  LEU A CB    1 
ATOM   4347  C CG    . LEU A 1 550  ? 212.220 324.583 233.176 1.00 47.49  ? 550  LEU A CG    1 
ATOM   4348  C CD1   . LEU A 1 550  ? 211.507 323.246 233.237 1.00 47.49  ? 550  LEU A CD1   1 
ATOM   4349  C CD2   . LEU A 1 550  ? 213.284 324.573 232.096 1.00 47.49  ? 550  LEU A CD2   1 
ATOM   4350  N N     . CYS A 1 551  ? 212.085 328.501 231.738 1.00 54.88  ? 551  CYS A N     1 
ATOM   4351  C CA    . CYS A 1 551  ? 213.002 329.306 230.941 1.00 54.88  ? 551  CYS A CA    1 
ATOM   4352  C C     . CYS A 1 551  ? 213.461 330.558 231.677 1.00 54.88  ? 551  CYS A C     1 
ATOM   4353  O O     . CYS A 1 551  ? 214.545 331.073 231.382 1.00 54.88  ? 551  CYS A O     1 
ATOM   4354  C CB    . CYS A 1 551  ? 212.336 329.681 229.614 1.00 54.88  ? 551  CYS A CB    1 
ATOM   4355  S SG    . CYS A 1 551  ? 213.004 331.139 228.774 1.00 54.88  ? 551  CYS A SG    1 
ATOM   4356  N N     . SER A 1 552  ? 212.679 331.044 232.643 1.00 61.33  ? 552  SER A N     1 
ATOM   4357  C CA    . SER A 1 552  ? 213.020 332.303 233.297 1.00 61.33  ? 552  SER A CA    1 
ATOM   4358  C C     . SER A 1 552  ? 214.251 332.165 234.188 1.00 61.33  ? 552  SER A C     1 
ATOM   4359  O O     . SER A 1 552  ? 215.289 332.785 233.928 1.00 61.33  ? 552  SER A O     1 
ATOM   4360  C CB    . SER A 1 552  ? 211.823 332.808 234.109 1.00 61.33  ? 552  SER A CB    1 
ATOM   4361  O OG    . SER A 1 552  ? 210.968 333.609 233.312 1.00 61.33  ? 552  SER A OG    1 
ATOM   4362  N N     . ARG A 1 553  ? 214.159 331.358 235.246 1.00 58.60  ? 553  ARG A N     1 
ATOM   4363  C CA    . ARG A 1 553  ? 215.254 331.261 236.222 1.00 58.60  ? 553  ARG A CA    1 
ATOM   4364  C C     . ARG A 1 553  ? 216.307 330.242 235.794 1.00 58.60  ? 553  ARG A C     1 
ATOM   4365  O O     . ARG A 1 553  ? 217.434 330.611 235.450 1.00 58.60  ? 553  ARG A O     1 
ATOM   4366  C CB    . ARG A 1 553  ? 214.691 330.914 237.602 1.00 58.60  ? 553  ARG A CB    1 
ATOM   4367  C CG    . ARG A 1 553  ? 213.298 331.465 237.874 1.00 58.60  ? 553  ARG A CG    1 
ATOM   4368  C CD    . ARG A 1 553  ? 213.284 332.987 237.903 1.00 58.60  ? 553  ARG A CD    1 
ATOM   4369  N NE    . ARG A 1 553  ? 211.929 333.520 237.974 1.00 58.60  ? 553  ARG A NE    1 
ATOM   4370  C CZ    . ARG A 1 553  ? 211.167 333.498 239.060 1.00 58.60  ? 553  ARG A CZ    1 
ATOM   4371  N NH1   . ARG A 1 553  ? 211.602 332.986 240.200 1.00 58.60  ? 553  ARG A NH1   1 
ATOM   4372  N NH2   . ARG A 1 553  ? 209.940 334.006 239.002 1.00 58.60  ? 553  ARG A NH2   1 
ATOM   4373  N N     . TRP A 1 554  ? 215.928 328.966 235.771 1.00 52.12  ? 554  TRP A N     1 
ATOM   4374  C CA    . TRP A 1 554  ? 216.826 327.833 235.529 1.00 52.12  ? 554  TRP A CA    1 
ATOM   4375  C C     . TRP A 1 554  ? 218.192 328.044 236.187 1.00 52.12  ? 554  TRP A C     1 
ATOM   4376  O O     . TRP A 1 554  ? 219.237 328.066 235.535 1.00 52.12  ? 554  TRP A O     1 
ATOM   4377  C CB    . TRP A 1 554  ? 216.981 327.549 234.036 1.00 52.12  ? 554  TRP A CB    1 
ATOM   4378  C CG    . TRP A 1 554  ? 217.692 326.244 233.750 1.00 52.12  ? 554  TRP A CG    1 
ATOM   4379  C CD1   . TRP A 1 554  ? 218.723 326.050 232.878 1.00 52.12  ? 554  TRP A CD1   1 
ATOM   4380  C CD2   . TRP A 1 554  ? 217.410 324.958 234.327 1.00 52.12  ? 554  TRP A CD2   1 
ATOM   4381  N NE1   . TRP A 1 554  ? 219.107 324.731 232.881 1.00 52.12  ? 554  TRP A NE1   1 
ATOM   4382  C CE2   . TRP A 1 554  ? 218.316 324.040 233.761 1.00 52.12  ? 554  TRP A CE2   1 
ATOM   4383  C CE3   . TRP A 1 554  ? 216.482 324.495 235.267 1.00 52.12  ? 554  TRP A CE3   1 
ATOM   4384  C CZ2   . TRP A 1 554  ? 218.323 322.688 234.104 1.00 52.12  ? 554  TRP A CZ2   1 
ATOM   4385  C CZ3   . TRP A 1 554  ? 216.492 323.154 235.607 1.00 52.12  ? 554  TRP A CZ3   1 
ATOM   4386  C CH2   . TRP A 1 554  ? 217.405 322.267 235.027 1.00 52.12  ? 554  TRP A CH2   1 
ATOM   4387  N N     . ARG A 1 555  ? 218.165 328.213 237.509 1.00 53.63  ? 555  ARG A N     1 
ATOM   4388  C CA    . ARG A 1 555  ? 219.399 328.447 238.250 1.00 53.63  ? 555  ARG A CA    1 
ATOM   4389  C C     . ARG A 1 555  ? 220.273 327.204 238.363 1.00 53.63  ? 555  ARG A C     1 
ATOM   4390  O O     . ARG A 1 555  ? 221.429 327.321 238.783 1.00 53.63  ? 555  ARG A O     1 
ATOM   4391  C CB    . ARG A 1 555  ? 219.081 328.983 239.647 1.00 53.63  ? 555  ARG A CB    1 
ATOM   4392  C CG    . ARG A 1 555  ? 218.533 330.400 239.655 1.00 53.63  ? 555  ARG A CG    1 
ATOM   4393  C CD    . ARG A 1 555  ? 219.646 331.425 239.505 1.00 53.63  ? 555  ARG A CD    1 
ATOM   4394  N NE    . ARG A 1 555  ? 219.178 332.650 238.867 1.00 53.63  ? 555  ARG A NE    1 
ATOM   4395  C CZ    . ARG A 1 555  ? 218.986 332.791 237.563 1.00 53.63  ? 555  ARG A CZ    1 
ATOM   4396  N NH1   . ARG A 1 555  ? 219.217 331.799 236.718 1.00 53.63  ? 555  ARG A NH1   1 
ATOM   4397  N NH2   . ARG A 1 555  ? 218.552 333.958 237.093 1.00 53.63  ? 555  ARG A NH2   1 
ATOM   4398  N N     . MET A 1 556  ? 219.759 326.031 238.005 1.00 53.93  ? 556  MET A N     1 
ATOM   4399  C CA    . MET A 1 556  ? 220.538 324.807 238.097 1.00 53.93  ? 556  MET A CA    1 
ATOM   4400  C C     . MET A 1 556  ? 221.400 324.623 236.849 1.00 53.93  ? 556  MET A C     1 
ATOM   4401  O O     . MET A 1 556  ? 221.017 324.986 235.734 1.00 53.93  ? 556  MET A O     1 
ATOM   4402  C CB    . MET A 1 556  ? 219.619 323.599 238.287 1.00 53.93  ? 556  MET A CB    1 
ATOM   4403  C CG    . MET A 1 556  ? 220.337 322.318 238.687 1.00 53.93  ? 556  MET A CG    1 
ATOM   4404  S SD    . MET A 1 556  ? 221.859 322.623 239.606 1.00 53.93  ? 556  MET A SD    1 
ATOM   4405  C CE    . MET A 1 556  ? 222.268 320.964 240.144 1.00 53.93  ? 556  MET A CE    1 
ATOM   4406  N N     . THR A 1 557  ? 222.583 324.051 237.055 1.00 54.13  ? 557  THR A N     1 
ATOM   4407  C CA    . THR A 1 557  ? 223.508 323.810 235.957 1.00 54.13  ? 557  THR A CA    1 
ATOM   4408  C C     . THR A 1 557  ? 222.995 322.691 235.055 1.00 54.13  ? 557  THR A C     1 
ATOM   4409  O O     . THR A 1 557  ? 222.267 321.795 235.489 1.00 54.13  ? 557  THR A O     1 
ATOM   4410  C CB    . THR A 1 557  ? 224.894 323.452 236.496 1.00 54.13  ? 557  THR A CB    1 
ATOM   4411  O OG1   . THR A 1 557  ? 225.142 324.183 237.704 1.00 54.13  ? 557  THR A OG1   1 
ATOM   4412  C CG2   . THR A 1 557  ? 225.972 323.797 235.477 1.00 54.13  ? 557  THR A CG2   1 
ATOM   4413  N N     . GLY A 1 558  ? 223.385 322.753 233.785 1.00 55.33  ? 558  GLY A N     1 
ATOM   4414  C CA    . GLY A 1 558  ? 222.995 321.757 232.810 1.00 55.33  ? 558  GLY A CA    1 
ATOM   4415  C C     . GLY A 1 558  ? 221.713 322.118 232.080 1.00 55.33  ? 558  GLY A C     1 
ATOM   4416  O O     . GLY A 1 558  ? 220.954 323.007 232.473 1.00 55.33  ? 558  GLY A O     1 
ATOM   4417  N N     . GLN A 1 559  ? 221.479 321.407 230.979 1.00 54.01  ? 559  GLN A N     1 
ATOM   4418  C CA    . GLN A 1 559  ? 220.280 321.632 230.190 1.00 54.01  ? 559  GLN A CA    1 
ATOM   4419  C C     . GLN A 1 559  ? 219.097 320.862 230.777 1.00 54.01  ? 559  GLN A C     1 
ATOM   4420  O O     . GLN A 1 559  ? 219.270 319.786 231.355 1.00 54.01  ? 559  GLN A O     1 
ATOM   4421  C CB    . GLN A 1 559  ? 220.508 321.208 228.743 1.00 54.01  ? 559  GLN A CB    1 
ATOM   4422  C CG    . GLN A 1 559  ? 220.457 322.360 227.751 1.00 54.01  ? 559  GLN A CG    1 
ATOM   4423  C CD    . GLN A 1 559  ? 220.492 321.894 226.310 1.00 54.01  ? 559  GLN A CD    1 
ATOM   4424  O OE1   . GLN A 1 559  ? 220.566 320.696 226.035 1.00 54.01  ? 559  GLN A OE1   1 
ATOM   4425  N NE2   . GLN A 1 559  ? 220.440 322.840 225.380 1.00 54.01  ? 559  GLN A NE2   1 
ATOM   4426  N N     . PRO A 1 560  ? 217.880 321.397 230.640 1.00 64.40  ? 560  PRO A N     1 
ATOM   4427  C CA    . PRO A 1 560  ? 216.708 320.717 231.206 1.00 64.40  ? 560  PRO A CA    1 
ATOM   4428  C C     . PRO A 1 560  ? 216.027 319.788 230.214 1.00 64.40  ? 560  PRO A C     1 
ATOM   4429  O O     . PRO A 1 560  ? 216.377 319.763 229.029 1.00 64.40  ? 560  PRO A O     1 
ATOM   4430  C CB    . PRO A 1 560  ? 215.791 321.881 231.604 1.00 64.40  ? 560  PRO A CB    1 
ATOM   4431  C CG    . PRO A 1 560  ? 216.270 323.075 230.787 1.00 64.40  ? 560  PRO A CG    1 
ATOM   4432  C CD    . PRO A 1 560  ? 217.526 322.697 230.051 1.00 64.40  ? 560  PRO A CD    1 
ATOM   4433  N N     . THR A 1 561  ? 215.049 319.019 230.691 1.00 40.63  ? 561  THR A N     1 
ATOM   4434  C CA    . THR A 1 561  ? 214.303 318.101 229.840 1.00 40.63  ? 561  THR A CA    1 
ATOM   4435  C C     . THR A 1 561  ? 212.894 317.957 230.395 1.00 40.63  ? 561  THR A C     1 
ATOM   4436  O O     . THR A 1 561  ? 212.723 317.698 231.590 1.00 40.63  ? 561  THR A O     1 
ATOM   4437  C CB    . THR A 1 561  ? 214.986 316.729 229.763 1.00 40.63  ? 561  THR A CB    1 
ATOM   4438  O OG1   . THR A 1 561  ? 216.353 316.891 229.363 1.00 40.63  ? 561  THR A OG1   1 
ATOM   4439  C CG2   . THR A 1 561  ? 214.273 315.833 228.761 1.00 40.63  ? 561  THR A CG2   1 
ATOM   4440  N N     . ILE A 1 562  ? 211.895 318.121 229.532 1.00 34.06  ? 562  ILE A N     1 
ATOM   4441  C CA    . ILE A 1 562  ? 210.491 318.000 229.906 1.00 34.06  ? 562  ILE A CA    1 
ATOM   4442  C C     . ILE A 1 562  ? 209.874 316.872 229.093 1.00 34.06  ? 562  ILE A C     1 
ATOM   4443  O O     . ILE A 1 562  ? 210.015 316.835 227.866 1.00 34.06  ? 562  ILE A O     1 
ATOM   4444  C CB    . ILE A 1 562  ? 209.724 319.317 229.686 1.00 34.06  ? 562  ILE A CB    1 
ATOM   4445  C CG1   . ILE A 1 562  ? 210.270 320.414 230.601 1.00 34.06  ? 562  ILE A CG1   1 
ATOM   4446  C CG2   . ILE A 1 562  ? 208.235 319.116 229.923 1.00 34.06  ? 562  ILE A CG2   1 
ATOM   4447  C CD1   . ILE A 1 562  ? 209.778 321.800 230.247 1.00 34.06  ? 562  ILE A CD1   1 
ATOM   4448  N N     . THR A 1 563  ? 209.196 315.955 229.777 1.00 34.16  ? 563  THR A N     1 
ATOM   4449  C CA    . THR A 1 563  ? 208.535 314.822 229.144 1.00 34.16  ? 563  THR A CA    1 
ATOM   4450  C C     . THR A 1 563  ? 207.030 315.049 229.151 1.00 34.16  ? 563  THR A C     1 
ATOM   4451  O O     . THR A 1 563  ? 206.436 315.264 230.212 1.00 34.16  ? 563  THR A O     1 
ATOM   4452  C CB    . THR A 1 563  ? 208.876 313.516 229.865 1.00 34.16  ? 563  THR A CB    1 
ATOM   4453  O OG1   . THR A 1 563  ? 210.287 313.456 230.107 1.00 34.16  ? 563  THR A OG1   1 
ATOM   4454  C CG2   . THR A 1 563  ? 208.461 312.324 229.024 1.00 34.16  ? 563  THR A CG2   1 
ATOM   4455  N N     . PHE A 1 564  ? 206.419 314.999 227.971 1.00 36.99  ? 564  PHE A N     1 
ATOM   4456  C CA    . PHE A 1 564  ? 204.982 315.235 227.821 1.00 36.99  ? 564  PHE A CA    1 
ATOM   4457  C C     . PHE A 1 564  ? 204.310 314.004 227.229 1.00 36.99  ? 564  PHE A C     1 
ATOM   4458  O O     . PHE A 1 564  ? 204.270 313.847 225.996 1.00 36.99  ? 564  PHE A O     1 
ATOM   4459  C CB    . PHE A 1 564  ? 204.723 316.458 226.943 1.00 36.99  ? 564  PHE A CB    1 
ATOM   4460  C CG    . PHE A 1 564  ? 203.372 317.078 227.153 1.00 36.99  ? 564  PHE A CG    1 
ATOM   4461  C CD1   . PHE A 1 564  ? 203.100 317.811 228.297 1.00 36.99  ? 564  PHE A CD1   1 
ATOM   4462  C CD2   . PHE A 1 564  ? 202.371 316.928 226.207 1.00 36.99  ? 564  PHE A CD2   1 
ATOM   4463  C CE1   . PHE A 1 564  ? 201.857 318.382 228.493 1.00 36.99  ? 564  PHE A CE1   1 
ATOM   4464  C CE2   . PHE A 1 564  ? 201.126 317.497 226.397 1.00 36.99  ? 564  PHE A CE2   1 
ATOM   4465  C CZ    . PHE A 1 564  ? 200.869 318.225 227.541 1.00 36.99  ? 564  PHE A CZ    1 
ATOM   4466  N N     . PRO A 1 565  ? 203.770 313.109 228.054 1.00 41.69  ? 565  PRO A N     1 
ATOM   4467  C CA    . PRO A 1 565  ? 203.044 311.955 227.515 1.00 41.69  ? 565  PRO A CA    1 
ATOM   4468  C C     . PRO A 1 565  ? 201.672 312.355 226.996 1.00 41.69  ? 565  PRO A C     1 
ATOM   4469  O O     . PRO A 1 565  ? 201.061 313.316 227.469 1.00 41.69  ? 565  PRO A O     1 
ATOM   4470  C CB    . PRO A 1 565  ? 202.931 311.017 228.722 1.00 41.69  ? 565  PRO A CB    1 
ATOM   4471  C CG    . PRO A 1 565  ? 202.927 311.934 229.898 1.00 41.69  ? 565  PRO A CG    1 
ATOM   4472  C CD    . PRO A 1 565  ? 203.777 313.126 229.527 1.00 41.69  ? 565  PRO A CD    1 
ATOM   4473  N N     . ILE A 1 566  ? 201.192 311.605 226.011 1.00 51.39  ? 566  ILE A N     1 
ATOM   4474  C CA    . ILE A 1 566  ? 199.882 311.832 225.411 1.00 51.39  ? 566  ILE A CA    1 
ATOM   4475  C C     . ILE A 1 566  ? 198.928 310.794 225.987 1.00 51.39  ? 566  ILE A C     1 
ATOM   4476  O O     . ILE A 1 566  ? 199.115 309.588 225.795 1.00 51.39  ? 566  ILE A O     1 
ATOM   4477  C CB    . ILE A 1 566  ? 199.938 311.756 223.880 1.00 51.39  ? 566  ILE A CB    1 
ATOM   4478  C CG1   . ILE A 1 566  ? 201.059 312.648 223.341 1.00 51.39  ? 566  ILE A CG1   1 
ATOM   4479  C CG2   . ILE A 1 566  ? 198.602 312.160 223.279 1.00 51.39  ? 566  ILE A CG2   1 
ATOM   4480  C CD1   . ILE A 1 566  ? 200.953 314.095 223.774 1.00 51.39  ? 566  ILE A CD1   1 
ATOM   4481  N N     . SER A 1 567  ? 197.900 311.260 226.692 1.00 59.56  ? 567  SER A N     1 
ATOM   4482  C CA    . SER A 1 567  ? 196.949 310.375 227.342 1.00 59.56  ? 567  SER A CA    1 
ATOM   4483  C C     . SER A 1 567  ? 195.751 310.115 226.431 1.00 59.56  ? 567  SER A C     1 
ATOM   4484  O O     . SER A 1 567  ? 195.587 310.735 225.377 1.00 59.56  ? 567  SER A O     1 
ATOM   4485  C CB    . SER A 1 567  ? 196.505 310.964 228.680 1.00 59.56  ? 567  SER A CB    1 
ATOM   4486  O OG    . SER A 1 567  ? 195.387 311.819 228.515 1.00 59.56  ? 567  SER A OG    1 
ATOM   4487  N N     . HIS A 1 568  ? 194.899 309.179 226.845 1.00 65.92  ? 568  HIS A N     1 
ATOM   4488  C CA    . HIS A 1 568  ? 193.698 308.835 226.099 1.00 65.92  ? 568  HIS A CA    1 
ATOM   4489  C C     . HIS A 1 568  ? 192.519 309.746 226.416 1.00 65.92  ? 568  HIS A C     1 
ATOM   4490  O O     . HIS A 1 568  ? 191.504 309.688 225.714 1.00 65.92  ? 568  HIS A O     1 
ATOM   4491  C CB    . HIS A 1 568  ? 193.310 307.376 226.377 1.00 65.92  ? 568  HIS A CB    1 
ATOM   4492  C CG    . HIS A 1 568  ? 192.295 306.824 225.425 1.00 65.92  ? 568  HIS A CG    1 
ATOM   4493  N ND1   . HIS A 1 568  ? 190.961 307.168 225.476 1.00 65.92  ? 568  HIS A ND1   1 
ATOM   4494  C CD2   . HIS A 1 568  ? 192.419 305.950 224.398 1.00 65.92  ? 568  HIS A CD2   1 
ATOM   4495  C CE1   . HIS A 1 568  ? 190.307 306.530 224.521 1.00 65.92  ? 568  HIS A CE1   1 
ATOM   4496  N NE2   . HIS A 1 568  ? 191.169 305.785 223.853 1.00 65.92  ? 568  HIS A NE2   1 
ATOM   4497  N N     . SER A 1 569  ? 192.629 310.586 227.444 1.00 71.77  ? 569  SER A N     1 
ATOM   4498  C CA    . SER A 1 569  ? 191.541 311.469 227.840 1.00 71.77  ? 569  SER A CA    1 
ATOM   4499  C C     . SER A 1 569  ? 191.504 312.771 227.051 1.00 71.77  ? 569  SER A C     1 
ATOM   4500  O O     . SER A 1 569  ? 190.528 313.520 227.171 1.00 71.77  ? 569  SER A O     1 
ATOM   4501  C CB    . SER A 1 569  ? 191.638 311.786 229.337 1.00 71.77  ? 569  SER A CB    1 
ATOM   4502  O OG    . SER A 1 569  ? 190.783 312.860 229.687 1.00 71.77  ? 569  SER A OG    1 
ATOM   4503  N N     . MET A 1 570  ? 192.530 313.060 226.254 1.00 71.47  ? 570  MET A N     1 
ATOM   4504  C CA    . MET A 1 570  ? 192.581 314.277 225.457 1.00 71.47  ? 570  MET A CA    1 
ATOM   4505  C C     . MET A 1 570  ? 192.155 314.051 224.012 1.00 71.47  ? 570  MET A C     1 
ATOM   4506  O O     . MET A 1 570  ? 192.259 314.971 223.194 1.00 71.47  ? 570  MET A O     1 
ATOM   4507  C CB    . MET A 1 570  ? 193.987 314.880 225.501 1.00 71.47  ? 570  MET A CB    1 
ATOM   4508  C CG    . MET A 1 570  ? 195.079 313.960 224.983 1.00 71.47  ? 570  MET A CG    1 
ATOM   4509  S SD    . MET A 1 570  ? 196.705 314.738 225.011 1.00 71.47  ? 570  MET A SD    1 
ATOM   4510  C CE    . MET A 1 570  ? 197.020 314.799 226.773 1.00 71.47  ? 570  MET A CE    1 
ATOM   4511  N N     . LEU A 1 571  ? 191.680 312.854 223.679 1.00 75.14  ? 571  LEU A N     1 
ATOM   4512  C CA    . LEU A 1 571  ? 191.217 312.566 222.333 1.00 75.14  ? 571  LEU A CA    1 
ATOM   4513  C C     . LEU A 1 571  ? 189.854 313.211 222.088 1.00 75.14  ? 571  LEU A C     1 
ATOM   4514  O O     . LEU A 1 571  ? 189.179 313.680 223.009 1.00 75.14  ? 571  LEU A O     1 
ATOM   4515  C CB    . LEU A 1 571  ? 191.143 311.057 222.103 1.00 75.14  ? 571  LEU A CB    1 
ATOM   4516  C CG    . LEU A 1 571  ? 192.417 310.261 222.394 1.00 75.14  ? 571  LEU A CG    1 
ATOM   4517  C CD1   . LEU A 1 571  ? 192.174 308.772 222.204 1.00 75.14  ? 571  LEU A CD1   1 
ATOM   4518  C CD2   . LEU A 1 571  ? 193.562 310.739 221.514 1.00 75.14  ? 571  LEU A CD2   1 
ATOM   4519  N N     . ASP A 1 572  ? 189.451 313.233 220.820 1.00 88.78  ? 572  ASP A N     1 
ATOM   4520  C CA    . ASP A 1 572  ? 188.175 313.822 220.446 1.00 88.78  ? 572  ASP A CA    1 
ATOM   4521  C C     . ASP A 1 572  ? 187.025 312.898 220.851 1.00 88.78  ? 572  ASP A C     1 
ATOM   4522  O O     . ASP A 1 572  ? 187.213 311.861 221.494 1.00 88.78  ? 572  ASP A O     1 
ATOM   4523  C CB    . ASP A 1 572  ? 188.146 314.122 218.947 1.00 88.78  ? 572  ASP A CB    1 
ATOM   4524  C CG    . ASP A 1 572  ? 188.602 312.945 218.101 1.00 88.78  ? 572  ASP A CG    1 
ATOM   4525  O OD1   . ASP A 1 572  ? 188.249 311.791 218.425 1.00 88.78  ? 572  ASP A OD1   1 
ATOM   4526  O OD2   . ASP A 1 572  ? 189.312 313.177 217.100 1.00 88.78  ? 572  ASP A OD2   1 
ATOM   4527  N N     . GLU A 1 573  ? 185.808 313.294 220.468 1.00 106.30 ? 573  GLU A N     1 
ATOM   4528  C CA    . GLU A 1 573  ? 184.630 312.498 220.801 1.00 106.30 ? 573  GLU A CA    1 
ATOM   4529  C C     . GLU A 1 573  ? 184.684 311.125 220.142 1.00 106.30 ? 573  GLU A C     1 
ATOM   4530  O O     . GLU A 1 573  ? 184.339 310.115 220.766 1.00 106.30 ? 573  GLU A O     1 
ATOM   4531  C CB    . GLU A 1 573  ? 183.362 313.244 220.388 1.00 106.30 ? 573  GLU A CB    1 
ATOM   4532  C CG    . GLU A 1 573  ? 183.094 314.504 221.194 1.00 106.30 ? 573  GLU A CG    1 
ATOM   4533  C CD    . GLU A 1 573  ? 182.611 315.655 220.333 1.00 106.30 ? 573  GLU A CD    1 
ATOM   4534  O OE1   . GLU A 1 573  ? 181.766 315.420 219.443 1.00 106.30 ? 573  GLU A OE1   1 
ATOM   4535  O OE2   . GLU A 1 573  ? 183.076 316.795 220.545 1.00 106.30 ? 573  GLU A OE2   1 
ATOM   4536  N N     . ASP A 1 574  ? 185.115 311.067 218.880 1.00 96.29  ? 574  ASP A N     1 
ATOM   4537  C CA    . ASP A 1 574  ? 185.216 309.796 218.176 1.00 96.29  ? 574  ASP A CA    1 
ATOM   4538  C C     . ASP A 1 574  ? 186.413 308.966 218.621 1.00 96.29  ? 574  ASP A C     1 
ATOM   4539  O O     . ASP A 1 574  ? 186.456 307.767 218.324 1.00 96.29  ? 574  ASP A O     1 
ATOM   4540  C CB    . ASP A 1 574  ? 185.290 310.037 216.667 1.00 96.29  ? 574  ASP A CB    1 
ATOM   4541  N N     . GLY A 1 575  ? 187.371 309.564 219.322 1.00 86.64  ? 575  GLY A N     1 
ATOM   4542  C CA    . GLY A 1 575  ? 188.548 308.829 219.762 1.00 86.64  ? 575  GLY A CA    1 
ATOM   4543  C C     . GLY A 1 575  ? 189.423 308.341 218.629 1.00 86.64  ? 575  GLY A C     1 
ATOM   4544  O O     . GLY A 1 575  ? 189.938 307.217 218.684 1.00 86.64  ? 575  GLY A O     1 
ATOM   4545  N N     . THR A 1 576  ? 189.606 309.165 217.595 1.00 78.80  ? 576  THR A N     1 
ATOM   4546  C CA    . THR A 1 576  ? 190.432 308.800 216.453 1.00 78.80  ? 576  THR A CA    1 
ATOM   4547  C C     . THR A 1 576  ? 191.495 309.831 216.104 1.00 78.80  ? 576  THR A C     1 
ATOM   4548  O O     . THR A 1 576  ? 192.360 309.534 215.273 1.00 78.80  ? 576  THR A O     1 
ATOM   4549  C CB    . THR A 1 576  ? 189.561 308.557 215.209 1.00 78.80  ? 576  THR A CB    1 
ATOM   4550  O OG1   . THR A 1 576  ? 188.783 309.727 214.931 1.00 78.80  ? 576  THR A OG1   1 
ATOM   4551  C CG2   . THR A 1 576  ? 188.632 307.371 215.426 1.00 78.80  ? 576  THR A CG2   1 
ATOM   4552  N N     . SER A 1 577  ? 191.463 311.021 216.701 1.00 80.94  ? 577  SER A N     1 
ATOM   4553  C CA    . SER A 1 577  ? 192.446 312.052 216.406 1.00 80.94  ? 577  SER A CA    1 
ATOM   4554  C C     . SER A 1 577  ? 192.629 312.932 217.633 1.00 80.94  ? 577  SER A C     1 
ATOM   4555  O O     . SER A 1 577  ? 191.775 312.978 218.523 1.00 80.94  ? 577  SER A O     1 
ATOM   4556  C CB    . SER A 1 577  ? 192.031 312.897 215.195 1.00 80.94  ? 577  SER A CB    1 
ATOM   4557  O OG    . SER A 1 577  ? 190.972 313.778 215.526 1.00 80.94  ? 577  SER A OG    1 
ATOM   4558  N N     . LEU A 1 578  ? 193.761 313.628 217.672 1.00 74.56  ? 578  LEU A N     1 
ATOM   4559  C CA    . LEU A 1 578  ? 194.056 314.514 218.788 1.00 74.56  ? 578  LEU A CA    1 
ATOM   4560  C C     . LEU A 1 578  ? 193.199 315.774 218.720 1.00 74.56  ? 578  LEU A C     1 
ATOM   4561  O O     . LEU A 1 578  ? 192.675 316.143 217.666 1.00 74.56  ? 578  LEU A O     1 
ATOM   4562  C CB    . LEU A 1 578  ? 195.536 314.892 218.797 1.00 74.56  ? 578  LEU A CB    1 
ATOM   4563  C CG    . LEU A 1 578  ? 196.401 314.193 219.846 1.00 74.56  ? 578  LEU A CG    1 
ATOM   4564  C CD1   . LEU A 1 578  ? 197.872 314.500 219.617 1.00 74.56  ? 578  LEU A CD1   1 
ATOM   4565  C CD2   . LEU A 1 578  ? 195.975 314.590 221.251 1.00 74.56  ? 578  LEU A CD2   1 
ATOM   4566  N N     . ASN A 1 579  ? 193.061 316.434 219.866 1.00 72.25  ? 579  ASN A N     1 
ATOM   4567  C CA    . ASN A 1 579  ? 192.302 317.672 219.931 1.00 72.25  ? 579  ASN A CA    1 
ATOM   4568  C C     . ASN A 1 579  ? 193.059 318.802 219.237 1.00 72.25  ? 579  ASN A C     1 
ATOM   4569  O O     . ASN A 1 579  ? 194.270 318.730 219.007 1.00 72.25  ? 579  ASN A O     1 
ATOM   4570  C CB    . ASN A 1 579  ? 192.008 318.048 221.383 1.00 72.25  ? 579  ASN A CB    1 
ATOM   4571  C CG    . ASN A 1 579  ? 190.585 317.722 221.792 1.00 72.25  ? 579  ASN A CG    1 
ATOM   4572  O OD1   . ASN A 1 579  ? 189.968 316.800 221.257 1.00 72.25  ? 579  ASN A OD1   1 
ATOM   4573  N ND2   . ASN A 1 579  ? 190.055 318.479 222.746 1.00 72.25  ? 579  ASN A ND2   1 
ATOM   4574  N N     . SER A 1 580  ? 192.317 319.859 218.896 1.00 77.99  ? 580  SER A N     1 
ATOM   4575  C CA    . SER A 1 580  ? 192.908 320.978 218.169 1.00 77.99  ? 580  SER A CA    1 
ATOM   4576  C C     . SER A 1 580  ? 193.968 321.691 219.001 1.00 77.99  ? 580  SER A C     1 
ATOM   4577  O O     . SER A 1 580  ? 195.032 322.052 218.484 1.00 77.99  ? 580  SER A O     1 
ATOM   4578  C CB    . SER A 1 580  ? 191.816 321.958 217.740 1.00 77.99  ? 580  SER A CB    1 
ATOM   4579  O OG    . SER A 1 580  ? 190.937 322.244 218.814 1.00 77.99  ? 580  SER A OG    1 
ATOM   4580  N N     . SER A 1 581  ? 193.695 321.908 220.290 1.00 70.88  ? 581  SER A N     1 
ATOM   4581  C CA    . SER A 1 581  ? 194.635 322.644 221.131 1.00 70.88  ? 581  SER A CA    1 
ATOM   4582  C C     . SER A 1 581  ? 195.946 321.886 221.303 1.00 70.88  ? 581  SER A C     1 
ATOM   4583  O O     . SER A 1 581  ? 197.030 322.471 221.187 1.00 70.88  ? 581  SER A O     1 
ATOM   4584  C CB    . SER A 1 581  ? 194.002 322.935 222.492 1.00 70.88  ? 581  SER A CB    1 
ATOM   4585  O OG    . SER A 1 581  ? 192.703 323.480 222.344 1.00 70.88  ? 581  SER A OG    1 
ATOM   4586  N N     . ILE A 1 582  ? 195.868 320.582 221.578 1.00 64.21  ? 582  ILE A N     1 
ATOM   4587  C CA    . ILE A 1 582  ? 197.079 319.788 221.767 1.00 64.21  ? 582  ILE A CA    1 
ATOM   4588  C C     . ILE A 1 582  ? 197.874 319.708 220.469 1.00 64.21  ? 582  ILE A C     1 
ATOM   4589  O O     . ILE A 1 582  ? 199.107 319.810 220.473 1.00 64.21  ? 582  ILE A O     1 
ATOM   4590  C CB    . ILE A 1 582  ? 196.734 318.388 222.311 1.00 64.21  ? 582  ILE A CB    1 
ATOM   4591  C CG1   . ILE A 1 582  ? 196.161 318.472 223.730 1.00 64.21  ? 582  ILE A CG1   1 
ATOM   4592  C CG2   . ILE A 1 582  ? 197.962 317.491 222.300 1.00 64.21  ? 582  ILE A CG2   1 
ATOM   4593  C CD1   . ILE A 1 582  ? 194.664 318.695 223.797 1.00 64.21  ? 582  ILE A CD1   1 
ATOM   4594  N N     . LEU A 1 583  ? 197.184 319.522 219.341 1.00 65.92  ? 583  LEU A N     1 
ATOM   4595  C CA    . LEU A 1 583  ? 197.871 319.474 218.054 1.00 65.92  ? 583  LEU A CA    1 
ATOM   4596  C C     . LEU A 1 583  ? 198.561 320.797 217.747 1.00 65.92  ? 583  LEU A C     1 
ATOM   4597  O O     . LEU A 1 583  ? 199.699 320.815 217.263 1.00 65.92  ? 583  LEU A O     1 
ATOM   4598  C CB    . LEU A 1 583  ? 196.884 319.114 216.944 1.00 65.92  ? 583  LEU A CB    1 
ATOM   4599  C CG    . LEU A 1 583  ? 197.492 318.846 215.567 1.00 65.92  ? 583  LEU A CG    1 
ATOM   4600  C CD1   . LEU A 1 583  ? 198.162 317.482 215.530 1.00 65.92  ? 583  LEU A CD1   1 
ATOM   4601  C CD2   . LEU A 1 583  ? 196.433 318.960 214.481 1.00 65.92  ? 583  LEU A CD2   1 
ATOM   4602  N N     . ALA A 1 584  ? 197.885 321.917 218.019 1.00 60.99  ? 584  ALA A N     1 
ATOM   4603  C CA    . ALA A 1 584  ? 198.495 323.223 217.793 1.00 60.99  ? 584  ALA A CA    1 
ATOM   4604  C C     . ALA A 1 584  ? 199.708 323.429 218.691 1.00 60.99  ? 584  ALA A C     1 
ATOM   4605  O O     . ALA A 1 584  ? 200.730 323.967 218.251 1.00 60.99  ? 584  ALA A O     1 
ATOM   4606  C CB    . ALA A 1 584  ? 197.465 324.329 218.019 1.00 60.99  ? 584  ALA A CB    1 
ATOM   4607  N N     . ALA A 1 585  ? 199.612 323.010 219.956 1.00 55.91  ? 585  ALA A N     1 
ATOM   4608  C CA    . ALA A 1 585  ? 200.749 323.134 220.863 1.00 55.91  ? 585  ALA A CA    1 
ATOM   4609  C C     . ALA A 1 585  ? 201.930 322.297 220.387 1.00 55.91  ? 585  ALA A C     1 
ATOM   4610  O O     . ALA A 1 585  ? 203.079 322.753 220.420 1.00 55.91  ? 585  ALA A O     1 
ATOM   4611  C CB    . ALA A 1 585  ? 200.339 322.731 222.279 1.00 55.91  ? 585  ALA A CB    1 
ATOM   4612  N N     . LEU A 1 586  ? 201.666 321.067 219.936 1.00 57.58  ? 586  LEU A N     1 
ATOM   4613  C CA    . LEU A 1 586  ? 202.740 320.217 219.432 1.00 57.58  ? 586  LEU A CA    1 
ATOM   4614  C C     . LEU A 1 586  ? 203.371 320.810 218.178 1.00 57.58  ? 586  LEU A C     1 
ATOM   4615  O O     . LEU A 1 586  ? 204.596 320.775 218.014 1.00 57.58  ? 586  LEU A O     1 
ATOM   4616  C CB    . LEU A 1 586  ? 202.214 318.809 219.153 1.00 57.58  ? 586  LEU A CB    1 
ATOM   4617  C CG    . LEU A 1 586  ? 201.774 317.985 220.364 1.00 57.58  ? 586  LEU A CG    1 
ATOM   4618  C CD1   . LEU A 1 586  ? 200.779 316.913 219.948 1.00 57.58  ? 586  LEU A CD1   1 
ATOM   4619  C CD2   . LEU A 1 586  ? 202.975 317.366 221.061 1.00 57.58  ? 586  LEU A CD2   1 
ATOM   4620  N N     . ARG A 1 587  ? 202.549 321.355 217.278 1.00 58.52  ? 587  ARG A N     1 
ATOM   4621  C CA    . ARG A 1 587  ? 203.082 321.972 216.067 1.00 58.52  ? 587  ARG A CA    1 
ATOM   4622  C C     . ARG A 1 587  ? 203.930 323.193 216.399 1.00 58.52  ? 587  ARG A C     1 
ATOM   4623  O O     . ARG A 1 587  ? 204.980 323.415 215.784 1.00 58.52  ? 587  ARG A O     1 
ATOM   4624  C CB    . ARG A 1 587  ? 201.940 322.346 215.123 1.00 58.52  ? 587  ARG A CB    1 
ATOM   4625  C CG    . ARG A 1 587  ? 202.366 322.513 213.674 1.00 58.52  ? 587  ARG A CG    1 
ATOM   4626  C CD    . ARG A 1 587  ? 202.241 321.206 212.908 1.00 58.52  ? 587  ARG A CD    1 
ATOM   4627  N NE    . ARG A 1 587  ? 200.851 320.864 212.634 1.00 58.52  ? 587  ARG A NE    1 
ATOM   4628  C CZ    . ARG A 1 587  ? 200.464 319.821 211.912 1.00 58.52  ? 587  ARG A CZ    1 
ATOM   4629  N NH1   . ARG A 1 587  ? 201.342 318.990 211.374 1.00 58.52  ? 587  ARG A NH1   1 
ATOM   4630  N NH2   . ARG A 1 587  ? 199.165 319.606 211.727 1.00 58.52  ? 587  ARG A NH2   1 
ATOM   4631  N N     . LYS A 1 588  ? 203.486 324.003 217.364 1.00 52.75  ? 588  LYS A N     1 
ATOM   4632  C CA    . LYS A 1 588  ? 204.279 325.151 217.791 1.00 52.75  ? 588  LYS A CA    1 
ATOM   4633  C C     . LYS A 1 588  ? 205.600 324.708 218.406 1.00 52.75  ? 588  LYS A C     1 
ATOM   4634  O O     . LYS A 1 588  ? 206.648 325.312 218.149 1.00 52.75  ? 588  LYS A O     1 
ATOM   4635  C CB    . LYS A 1 588  ? 203.482 325.999 218.782 1.00 52.75  ? 588  LYS A CB    1 
ATOM   4636  C CG    . LYS A 1 588  ? 202.490 326.948 218.131 1.00 52.75  ? 588  LYS A CG    1 
ATOM   4637  C CD    . LYS A 1 588  ? 201.735 327.757 219.173 1.00 52.75  ? 588  LYS A CD    1 
ATOM   4638  C CE    . LYS A 1 588  ? 200.235 327.540 219.061 1.00 52.75  ? 588  LYS A CE    1 
ATOM   4639  N NZ    . LYS A 1 588  ? 199.475 328.429 219.982 1.00 52.75  ? 588  LYS A NZ    1 
ATOM   4640  N N     . MET A 1 589  ? 205.570 323.652 219.224 1.00 50.74  ? 589  MET A N     1 
ATOM   4641  C CA    . MET A 1 589  ? 206.802 323.134 219.810 1.00 50.74  ? 589  MET A CA    1 
ATOM   4642  C C     . MET A 1 589  ? 207.741 322.601 218.735 1.00 50.74  ? 589  MET A C     1 
ATOM   4643  O O     . MET A 1 589  ? 208.967 322.681 218.874 1.00 50.74  ? 589  MET A O     1 
ATOM   4644  C CB    . MET A 1 589  ? 206.479 322.044 220.832 1.00 50.74  ? 589  MET A CB    1 
ATOM   4645  C CG    . MET A 1 589  ? 205.912 322.569 222.140 1.00 50.74  ? 589  MET A CG    1 
ATOM   4646  S SD    . MET A 1 589  ? 205.847 321.309 223.429 1.00 50.74  ? 589  MET A SD    1 
ATOM   4647  C CE    . MET A 1 589  ? 204.089 320.969 223.481 1.00 50.74  ? 589  MET A CE    1 
ATOM   4648  N N     . GLN A 1 590  ? 207.182 322.044 217.657 1.00 55.13  ? 590  GLN A N     1 
ATOM   4649  C CA    . GLN A 1 590  ? 208.010 321.564 216.555 1.00 55.13  ? 590  GLN A CA    1 
ATOM   4650  C C     . GLN A 1 590  ? 208.758 322.711 215.886 1.00 55.13  ? 590  GLN A C     1 
ATOM   4651  O O     . GLN A 1 590  ? 209.926 322.564 215.506 1.00 55.13  ? 590  GLN A O     1 
ATOM   4652  C CB    . GLN A 1 590  ? 207.149 320.816 215.538 1.00 55.13  ? 590  GLN A CB    1 
ATOM   4653  C CG    . GLN A 1 590  ? 207.242 319.303 215.642 1.00 55.13  ? 590  GLN A CG    1 
ATOM   4654  C CD    . GLN A 1 590  ? 206.438 318.594 214.570 1.00 55.13  ? 590  GLN A CD    1 
ATOM   4655  O OE1   . GLN A 1 590  ? 206.140 319.166 213.521 1.00 55.13  ? 590  GLN A OE1   1 
ATOM   4656  N NE2   . GLN A 1 590  ? 206.082 317.341 214.828 1.00 55.13  ? 590  GLN A NE2   1 
ATOM   4657  N N     . ASP A 1 591  ? 208.103 323.863 215.732 1.00 60.10  ? 591  ASP A N     1 
ATOM   4658  C CA    . ASP A 1 591  ? 208.711 325.046 215.120 1.00 60.10  ? 591  ASP A CA    1 
ATOM   4659  C C     . ASP A 1 591  ? 209.700 325.754 216.038 1.00 60.10  ? 591  ASP A C     1 
ATOM   4660  O O     . ASP A 1 591  ? 210.157 326.852 215.693 1.00 60.10  ? 591  ASP A O     1 
ATOM   4661  C CB    . ASP A 1 591  ? 207.622 326.025 214.679 1.00 60.10  ? 591  ASP A CB    1 
ATOM   4662  C CG    . ASP A 1 591  ? 206.839 325.523 213.483 1.00 60.10  ? 591  ASP A CG    1 
ATOM   4663  O OD1   . ASP A 1 591  ? 207.188 324.450 212.949 1.00 60.10  ? 591  ASP A OD1   1 
ATOM   4664  O OD2   . ASP A 1 591  ? 205.875 326.204 213.076 1.00 60.10  ? 591  ASP A OD2   1 
ATOM   4665  N N     . GLY A 1 592  ? 210.039 325.165 217.179 1.00 54.37  ? 592  GLY A N     1 
ATOM   4666  C CA    . GLY A 1 592  ? 211.005 325.756 218.086 1.00 54.37  ? 592  GLY A CA    1 
ATOM   4667  C C     . GLY A 1 592  ? 210.564 327.036 218.762 1.00 54.37  ? 592  GLY A C     1 
ATOM   4668  O O     . GLY A 1 592  ? 211.396 327.921 219.002 1.00 54.37  ? 592  GLY A O     1 
ATOM   4669  N N     . TYR A 1 593  ? 209.276 327.153 219.087 1.00 53.68  ? 593  TYR A N     1 
ATOM   4670  C CA    . TYR A 1 593  ? 208.779 328.310 219.822 1.00 53.68  ? 593  TYR A CA    1 
ATOM   4671  C C     . TYR A 1 593  ? 207.401 328.029 220.409 1.00 53.68  ? 593  TYR A C     1 
ATOM   4672  O O     . TYR A 1 593  ? 206.472 327.664 219.682 1.00 53.68  ? 593  TYR A O     1 
ATOM   4673  C CB    . TYR A 1 593  ? 208.726 329.545 218.918 1.00 53.68  ? 593  TYR A CB    1 
ATOM   4674  C CG    . TYR A 1 593  ? 208.548 330.844 219.671 1.00 53.68  ? 593  TYR A CG    1 
ATOM   4675  C CD1   . TYR A 1 593  ? 209.648 331.563 220.122 1.00 53.68  ? 593  TYR A CD1   1 
ATOM   4676  C CD2   . TYR A 1 593  ? 207.282 331.350 219.936 1.00 53.68  ? 593  TYR A CD2   1 
ATOM   4677  C CE1   . TYR A 1 593  ? 209.493 332.750 220.812 1.00 53.68  ? 593  TYR A CE1   1 
ATOM   4678  C CE2   . TYR A 1 593  ? 207.117 332.537 220.626 1.00 53.68  ? 593  TYR A CE2   1 
ATOM   4679  C CZ    . TYR A 1 593  ? 208.225 333.232 221.061 1.00 53.68  ? 593  TYR A CZ    1 
ATOM   4680  O OH    . TYR A 1 593  ? 208.066 334.414 221.748 1.00 53.68  ? 593  TYR A OH    1 
ATOM   4681  N N     . PHE A 1 594  ? 207.261 328.202 221.721 1.00 46.53  ? 594  PHE A N     1 
ATOM   4682  C CA    . PHE A 1 594  ? 205.977 328.029 222.385 1.00 46.53  ? 594  PHE A CA    1 
ATOM   4683  C C     . PHE A 1 594  ? 205.979 328.862 223.657 1.00 46.53  ? 594  PHE A C     1 
ATOM   4684  O O     . PHE A 1 594  ? 206.909 328.768 224.462 1.00 46.53  ? 594  PHE A O     1 
ATOM   4685  C CB    . PHE A 1 594  ? 205.703 326.555 222.706 1.00 46.53  ? 594  PHE A CB    1 
ATOM   4686  C CG    . PHE A 1 594  ? 204.352 326.308 223.316 1.00 46.53  ? 594  PHE A CG    1 
ATOM   4687  C CD1   . PHE A 1 594  ? 203.222 326.920 222.800 1.00 46.53  ? 594  PHE A CD1   1 
ATOM   4688  C CD2   . PHE A 1 594  ? 204.212 325.463 224.404 1.00 46.53  ? 594  PHE A CD2   1 
ATOM   4689  C CE1   . PHE A 1 594  ? 201.978 326.695 223.358 1.00 46.53  ? 594  PHE A CE1   1 
ATOM   4690  C CE2   . PHE A 1 594  ? 202.970 325.233 224.967 1.00 46.53  ? 594  PHE A CE2   1 
ATOM   4691  C CZ    . PHE A 1 594  ? 201.852 325.850 224.443 1.00 46.53  ? 594  PHE A CZ    1 
ATOM   4692  N N     . GLY A 1 595  ? 204.935 329.668 223.832 1.00 55.07  ? 595  GLY A N     1 
ATOM   4693  C CA    . GLY A 1 595  ? 204.865 330.563 224.968 1.00 55.07  ? 595  GLY A CA    1 
ATOM   4694  C C     . GLY A 1 595  ? 205.937 331.633 224.922 1.00 55.07  ? 595  GLY A C     1 
ATOM   4695  O O     . GLY A 1 595  ? 205.876 332.548 224.096 1.00 55.07  ? 595  GLY A O     1 
ATOM   4696  N N     . GLY A 1 596  ? 206.925 331.527 225.807 1.00 57.70  ? 596  GLY A N     1 
ATOM   4697  C CA    . GLY A 1 596  ? 208.029 332.466 225.823 1.00 57.70  ? 596  GLY A CA    1 
ATOM   4698  C C     . GLY A 1 596  ? 209.375 331.786 225.963 1.00 57.70  ? 596  GLY A C     1 
ATOM   4699  O O     . GLY A 1 596  ? 210.305 332.348 226.549 1.00 57.70  ? 596  GLY A O     1 
ATOM   4700  N N     . ALA A 1 597  ? 209.491 330.572 225.428 1.00 48.70  ? 597  ALA A N     1 
ATOM   4701  C CA    . ALA A 1 597  ? 210.713 329.790 225.536 1.00 48.70  ? 597  ALA A CA    1 
ATOM   4702  C C     . ALA A 1 597  ? 211.040 329.163 224.189 1.00 48.70  ? 597  ALA A C     1 
ATOM   4703  O O     . ALA A 1 597  ? 210.163 328.955 223.347 1.00 48.70  ? 597  ALA A O     1 
ATOM   4704  C CB    . ALA A 1 597  ? 210.591 328.700 226.608 1.00 48.70  ? 597  ALA A CB    1 
ATOM   4705  N N     . ARG A 1 598  ? 212.321 328.864 223.996 1.00 57.98  ? 598  ARG A N     1 
ATOM   4706  C CA    . ARG A 1 598  ? 212.801 328.181 222.803 1.00 57.98  ? 598  ARG A CA    1 
ATOM   4707  C C     . ARG A 1 598  ? 212.921 326.691 223.096 1.00 57.98  ? 598  ARG A C     1 
ATOM   4708  O O     . ARG A 1 598  ? 213.583 326.295 224.061 1.00 57.98  ? 598  ARG A O     1 
ATOM   4709  C CB    . ARG A 1 598  ? 214.148 328.745 222.350 1.00 57.98  ? 598  ARG A CB    1 
ATOM   4710  C CG    . ARG A 1 598  ? 214.723 328.060 221.120 1.00 57.98  ? 598  ARG A CG    1 
ATOM   4711  C CD    . ARG A 1 598  ? 215.751 328.932 220.410 1.00 57.98  ? 598  ARG A CD    1 
ATOM   4712  N NE    . ARG A 1 598  ? 216.916 329.213 221.241 1.00 57.98  ? 598  ARG A NE    1 
ATOM   4713  C CZ    . ARG A 1 598  ? 217.115 330.348 221.897 1.00 57.98  ? 598  ARG A CZ    1 
ATOM   4714  N NH1   . ARG A 1 598  ? 216.244 331.342 221.840 1.00 57.98  ? 598  ARG A NH1   1 
ATOM   4715  N NH2   . ARG A 1 598  ? 218.218 330.491 222.626 1.00 57.98  ? 598  ARG A NH2   1 
ATOM   4716  N N     . VAL A 1 599  ? 212.285 325.872 222.258 1.00 44.86  ? 599  VAL A N     1 
ATOM   4717  C CA    . VAL A 1 599  ? 212.197 324.436 222.477 1.00 44.86  ? 599  VAL A CA    1 
ATOM   4718  C C     . VAL A 1 599  ? 212.768 323.722 221.258 1.00 44.86  ? 599  VAL A C     1 
ATOM   4719  O O     . VAL A 1 599  ? 212.739 324.235 220.138 1.00 44.86  ? 599  VAL A O     1 
ATOM   4720  C CB    . VAL A 1 599  ? 210.738 323.989 222.742 1.00 44.86  ? 599  VAL A CB    1 
ATOM   4721  C CG1   . VAL A 1 599  ? 210.666 322.515 223.112 1.00 44.86  ? 599  VAL A CG1   1 
ATOM   4722  C CG2   . VAL A 1 599  ? 210.102 324.848 223.826 1.00 44.86  ? 599  VAL A CG2   1 
ATOM   4723  N N     . GLN A 1 600  ? 213.305 322.523 221.491 1.00 45.11  ? 600  GLN A N     1 
ATOM   4724  C CA    . GLN A 1 600  ? 213.756 321.664 220.397 1.00 45.11  ? 600  GLN A CA    1 
ATOM   4725  C C     . GLN A 1 600  ? 213.239 320.255 220.683 1.00 45.11  ? 600  GLN A C     1 
ATOM   4726  O O     . GLN A 1 600  ? 213.356 319.760 221.809 1.00 45.11  ? 600  GLN A O     1 
ATOM   4727  C CB    . GLN A 1 600  ? 215.274 321.706 220.236 1.00 45.11  ? 600  GLN A CB    1 
ATOM   4728  C CG    . GLN A 1 600  ? 216.074 320.854 221.210 1.00 45.11  ? 600  GLN A CG    1 
ATOM   4729  C CD    . GLN A 1 600  ? 217.563 321.131 221.136 1.00 45.11  ? 600  GLN A CD    1 
ATOM   4730  O OE1   . GLN A 1 600  ? 217.988 322.279 221.008 1.00 45.11  ? 600  GLN A OE1   1 
ATOM   4731  N NE2   . GLN A 1 600  ? 218.366 320.076 221.215 1.00 45.11  ? 600  GLN A NE2   1 
ATOM   4732  N N     . THR A 1 601  ? 212.623 319.642 219.675 1.00 43.78  ? 601  THR A N     1 
ATOM   4733  C CA    . THR A 1 601  ? 212.053 318.314 219.845 1.00 43.78  ? 601  THR A CA    1 
ATOM   4734  C C     . THR A 1 601  ? 213.056 317.243 219.426 1.00 43.78  ? 601  THR A C     1 
ATOM   4735  O O     . THR A 1 601  ? 213.777 317.387 218.435 1.00 43.78  ? 601  THR A O     1 
ATOM   4736  C CB    . THR A 1 601  ? 210.765 318.180 219.031 1.00 43.78  ? 601  THR A CB    1 
ATOM   4737  O OG1   . THR A 1 601  ? 209.921 319.311 219.284 1.00 43.78  ? 601  THR A OG1   1 
ATOM   4738  C CG2   . THR A 1 601  ? 210.019 316.910 219.412 1.00 43.78  ? 601  THR A CG2   1 
ATOM   4739  N N     . GLY A 1 602  ? 213.095 316.162 220.191 1.00 44.82  ? 602  GLY A N     1 
ATOM   4740  C CA    . GLY A 1 602  ? 214.002 315.080 219.886 1.00 44.82  ? 602  GLY A CA    1 
ATOM   4741  C C     . GLY A 1 602  ? 213.719 313.858 220.728 1.00 44.82  ? 602  GLY A C     1 
ATOM   4742  O O     . GLY A 1 602  ? 212.661 313.741 221.348 1.00 44.82  ? 602  GLY A O     1 
ATOM   4743  N N     . LYS A 1 603  ? 214.685 312.946 220.741 1.00 47.09  ? 603  LYS A N     1 
ATOM   4744  C CA    . LYS A 1 603  ? 214.577 311.690 221.466 1.00 47.09  ? 603  LYS A CA    1 
ATOM   4745  C C     . LYS A 1 603  ? 215.182 311.822 222.857 1.00 47.09  ? 603  LYS A C     1 
ATOM   4746  O O     . LYS A 1 603  ? 216.068 312.647 223.094 1.00 47.09  ? 603  LYS A O     1 
ATOM   4747  C CB    . LYS A 1 603  ? 215.273 310.561 220.703 1.00 47.09  ? 603  LYS A CB    1 
ATOM   4748  C CG    . LYS A 1 603  ? 214.436 309.949 219.594 1.00 47.09  ? 603  LYS A CG    1 
ATOM   4749  C CD    . LYS A 1 603  ? 214.965 308.580 219.195 1.00 47.09  ? 603  LYS A CD    1 
ATOM   4750  C CE    . LYS A 1 603  ? 216.420 308.653 218.759 1.00 47.09  ? 603  LYS A CE    1 
ATOM   4751  N NZ    . LYS A 1 603  ? 216.648 309.724 217.750 1.00 47.09  ? 603  LYS A NZ    1 
ATOM   4752  N N     . LEU A 1 604  ? 214.687 310.995 223.782 1.00 44.03  ? 604  LEU A N     1 
ATOM   4753  C CA    . LEU A 1 604  ? 215.219 311.001 225.141 1.00 44.03  ? 604  LEU A CA    1 
ATOM   4754  C C     . LEU A 1 604  ? 216.680 310.571 225.164 1.00 44.03  ? 604  LEU A C     1 
ATOM   4755  O O     . LEU A 1 604  ? 217.477 311.092 225.954 1.00 44.03  ? 604  LEU A O     1 
ATOM   4756  C CB    . LEU A 1 604  ? 214.378 310.095 226.041 1.00 44.03  ? 604  LEU A CB    1 
ATOM   4757  C CG    . LEU A 1 604  ? 213.121 310.721 226.647 1.00 44.03  ? 604  LEU A CG    1 
ATOM   4758  C CD1   . LEU A 1 604  ? 212.039 309.672 226.841 1.00 44.03  ? 604  LEU A CD1   1 
ATOM   4759  C CD2   . LEU A 1 604  ? 213.445 311.413 227.962 1.00 44.03  ? 604  LEU A CD2   1 
ATOM   4760  N N     . SER A 1 605  ? 217.050 309.615 224.308 1.00 48.69  ? 605  SER A N     1 
ATOM   4761  C CA    . SER A 1 605  ? 218.443 309.184 224.236 1.00 48.69  ? 605  SER A CA    1 
ATOM   4762  C C     . SER A 1 605  ? 219.349 310.325 223.793 1.00 48.69  ? 605  SER A C     1 
ATOM   4763  O O     . SER A 1 605  ? 220.460 310.484 224.313 1.00 48.69  ? 605  SER A O     1 
ATOM   4764  C CB    . SER A 1 605  ? 218.575 307.992 223.288 1.00 48.69  ? 605  SER A CB    1 
ATOM   4765  O OG    . SER A 1 605  ? 218.147 308.331 221.980 1.00 48.69  ? 605  SER A OG    1 
ATOM   4766  N N     . GLU A 1 606  ? 218.895 311.126 222.825 1.00 49.51  ? 606  GLU A N     1 
ATOM   4767  C CA    . GLU A 1 606  ? 219.680 312.277 222.387 1.00 49.51  ? 606  GLU A CA    1 
ATOM   4768  C C     . GLU A 1 606  ? 219.848 313.292 223.511 1.00 49.51  ? 606  GLU A C     1 
ATOM   4769  O O     . GLU A 1 606  ? 220.938 313.846 223.698 1.00 49.51  ? 606  GLU A O     1 
ATOM   4770  C CB    . GLU A 1 606  ? 219.022 312.926 221.169 1.00 49.51  ? 606  GLU A CB    1 
ATOM   4771  N N     . PHE A 1 607  ? 218.779 313.551 224.268 1.00 45.19  ? 607  PHE A N     1 
ATOM   4772  C CA    . PHE A 1 607  ? 218.872 314.495 225.378 1.00 45.19  ? 607  PHE A CA    1 
ATOM   4773  C C     . PHE A 1 607  ? 219.716 313.944 226.519 1.00 45.19  ? 607  PHE A C     1 
ATOM   4774  O O     . PHE A 1 607  ? 220.238 314.717 227.331 1.00 45.19  ? 607  PHE A O     1 
ATOM   4775  C CB    . PHE A 1 607  ? 217.475 314.856 225.885 1.00 45.19  ? 607  PHE A CB    1 
ATOM   4776  C CG    . PHE A 1 607  ? 216.589 315.474 224.841 1.00 45.19  ? 607  PHE A CG    1 
ATOM   4777  C CD1   . PHE A 1 607  ? 217.102 316.373 223.921 1.00 45.19  ? 607  PHE A CD1   1 
ATOM   4778  C CD2   . PHE A 1 607  ? 215.240 315.165 224.788 1.00 45.19  ? 607  PHE A CD2   1 
ATOM   4779  C CE1   . PHE A 1 607  ? 216.289 316.946 222.963 1.00 45.19  ? 607  PHE A CE1   1 
ATOM   4780  C CE2   . PHE A 1 607  ? 214.421 315.735 223.832 1.00 45.19  ? 607  PHE A CE2   1 
ATOM   4781  C CZ    . PHE A 1 607  ? 214.946 316.627 222.919 1.00 45.19  ? 607  PHE A CZ    1 
ATOM   4782  N N     . LEU A 1 608  ? 219.855 312.619 226.604 1.00 46.07  ? 608  LEU A N     1 
ATOM   4783  C CA    . LEU A 1 608  ? 220.629 312.013 227.681 1.00 46.07  ? 608  LEU A CA    1 
ATOM   4784  C C     . LEU A 1 608  ? 222.109 312.367 227.604 1.00 46.07  ? 608  LEU A C     1 
ATOM   4785  O O     . LEU A 1 608  ? 222.798 312.327 228.630 1.00 46.07  ? 608  LEU A O     1 
ATOM   4786  C CB    . LEU A 1 608  ? 220.447 310.492 227.656 1.00 46.07  ? 608  LEU A CB    1 
ATOM   4787  C CG    . LEU A 1 608  ? 221.113 309.664 228.757 1.00 46.07  ? 608  LEU A CG    1 
ATOM   4788  C CD1   . LEU A 1 608  ? 220.654 310.128 230.131 1.00 46.07  ? 608  LEU A CD1   1 
ATOM   4789  C CD2   . LEU A 1 608  ? 220.827 308.183 228.564 1.00 46.07  ? 608  LEU A CD2   1 
ATOM   4790  N N     . THR A 1 609  ? 222.613 312.716 226.417 1.00 53.11  ? 609  THR A N     1 
ATOM   4791  C CA    . THR A 1 609  ? 224.035 313.018 226.277 1.00 53.11  ? 609  THR A CA    1 
ATOM   4792  C C     . THR A 1 609  ? 224.425 314.242 227.100 1.00 53.11  ? 609  THR A C     1 
ATOM   4793  O O     . THR A 1 609  ? 225.432 314.221 227.818 1.00 53.11  ? 609  THR A O     1 
ATOM   4794  C CB    . THR A 1 609  ? 224.382 313.219 224.800 1.00 53.11  ? 609  THR A CB    1 
ATOM   4795  O OG1   . THR A 1 609  ? 224.502 311.942 224.162 1.00 53.11  ? 609  THR A OG1   1 
ATOM   4796  C CG2   . THR A 1 609  ? 225.701 313.959 224.652 1.00 53.11  ? 609  THR A CG2   1 
ATOM   4797  N N     . THR A 1 610  ? 223.635 315.314 227.022 1.00 54.05  ? 610  THR A N     1 
ATOM   4798  C CA    . THR A 1 610  ? 223.837 316.498 227.852 1.00 54.05  ? 610  THR A CA    1 
ATOM   4799  C C     . THR A 1 610  ? 222.521 316.839 228.530 1.00 54.05  ? 610  THR A C     1 
ATOM   4800  O O     . THR A 1 610  ? 221.553 317.205 227.855 1.00 54.05  ? 610  THR A O     1 
ATOM   4801  C CB    . THR A 1 610  ? 224.333 317.700 227.035 1.00 54.05  ? 610  THR A CB    1 
ATOM   4802  O OG1   . THR A 1 610  ? 223.211 318.422 226.512 1.00 54.05  ? 610  THR A OG1   1 
ATOM   4803  C CG2   . THR A 1 610  ? 225.229 317.261 225.888 1.00 54.05  ? 610  THR A CG2   1 
ATOM   4804  N N     . SER A 1 611  ? 222.490 316.733 229.853 1.00 49.98  ? 611  SER A N     1 
ATOM   4805  C CA    . SER A 1 611  ? 221.297 317.034 230.639 1.00 49.98  ? 611  SER A CA    1 
ATOM   4806  C C     . SER A 1 611  ? 221.713 317.136 232.101 1.00 49.98  ? 611  SER A C     1 
ATOM   4807  O O     . SER A 1 611  ? 222.872 316.897 232.456 1.00 49.98  ? 611  SER A O     1 
ATOM   4808  C CB    . SER A 1 611  ? 220.210 315.976 230.439 1.00 49.98  ? 611  SER A CB    1 
ATOM   4809  O OG    . SER A 1 611  ? 218.991 316.377 231.040 1.00 49.98  ? 611  SER A OG    1 
ATOM   4810  N N     . CYS A 1 612  ? 220.753 317.495 232.950 1.00 48.81  ? 612  CYS A N     1 
ATOM   4811  C CA    . CYS A 1 612  ? 220.978 317.594 234.388 1.00 48.81  ? 612  CYS A CA    1 
ATOM   4812  C C     . CYS A 1 612  ? 220.694 316.236 235.018 1.00 48.81  ? 612  CYS A C     1 
ATOM   4813  O O     . CYS A 1 612  ? 219.532 315.839 235.159 1.00 48.81  ? 612  CYS A O     1 
ATOM   4814  C CB    . CYS A 1 612  ? 220.097 318.681 234.999 1.00 48.81  ? 612  CYS A CB    1 
ATOM   4815  S SG    . CYS A 1 612  ? 220.609 319.215 236.648 1.00 48.81  ? 612  CYS A SG    1 
ATOM   4816  N N     . CYS A 1 613  ? 221.752 315.525 235.395 1.00 53.94  ? 613  CYS A N     1 
ATOM   4817  C CA    . CYS A 1 613  ? 221.645 314.193 235.974 1.00 53.94  ? 613  CYS A CA    1 
ATOM   4818  C C     . CYS A 1 613  ? 222.044 314.241 237.442 1.00 53.94  ? 613  CYS A C     1 
ATOM   4819  O O     . CYS A 1 613  ? 223.104 314.776 237.785 1.00 53.94  ? 613  CYS A O     1 
ATOM   4820  C CB    . CYS A 1 613  ? 222.527 313.196 235.218 1.00 53.94  ? 613  CYS A CB    1 
ATOM   4821  S SG    . CYS A 1 613  ? 222.556 311.535 235.930 1.00 53.94  ? 613  CYS A SG    1 
ATOM   4822  N N     . THR A 1 614  ? 221.196 313.684 238.301 1.00 48.60  ? 614  THR A N     1 
ATOM   4823  C CA    . THR A 1 614  ? 221.443 313.623 239.733 1.00 48.60  ? 614  THR A CA    1 
ATOM   4824  C C     . THR A 1 614  ? 221.460 312.169 240.182 1.00 48.60  ? 614  THR A C     1 
ATOM   4825  O O     . THR A 1 614  ? 220.604 311.375 239.779 1.00 48.60  ? 614  THR A O     1 
ATOM   4826  C CB    . THR A 1 614  ? 220.378 314.399 240.517 1.00 48.60  ? 614  THR A CB    1 
ATOM   4827  O OG1   . THR A 1 614  ? 220.141 315.662 239.883 1.00 48.60  ? 614  THR A OG1   1 
ATOM   4828  C CG2   . THR A 1 614  ? 220.835 314.635 241.949 1.00 48.60  ? 614  THR A CG2   1 
ATOM   4829  N N     . HIS A 1 615  ? 222.436 311.825 241.017 1.00 47.75  ? 615  HIS A N     1 
ATOM   4830  C CA    . HIS A 1 615  ? 222.602 310.469 241.522 1.00 47.75  ? 615  HIS A CA    1 
ATOM   4831  C C     . HIS A 1 615  ? 222.170 310.413 242.980 1.00 47.75  ? 615  HIS A C     1 
ATOM   4832  O O     . HIS A 1 615  ? 222.641 311.204 243.804 1.00 47.75  ? 615  HIS A O     1 
ATOM   4833  C CB    . HIS A 1 615  ? 224.054 310.005 241.383 1.00 47.75  ? 615  HIS A CB    1 
ATOM   4834  C CG    . HIS A 1 615  ? 224.369 308.767 242.163 1.00 47.75  ? 615  HIS A CG    1 
ATOM   4835  N ND1   . HIS A 1 615  ? 223.887 307.524 241.813 1.00 47.75  ? 615  HIS A ND1   1 
ATOM   4836  C CD2   . HIS A 1 615  ? 225.117 308.580 243.276 1.00 47.75  ? 615  HIS A CD2   1 
ATOM   4837  C CE1   . HIS A 1 615  ? 224.325 306.625 242.676 1.00 47.75  ? 615  HIS A CE1   1 
ATOM   4838  N NE2   . HIS A 1 615  ? 225.073 307.240 243.574 1.00 47.75  ? 615  HIS A NE2   1 
ATOM   4839  N N     . LEU A 1 616  ? 221.276 309.478 243.293 1.00 47.06  ? 616  LEU A N     1 
ATOM   4840  C CA    . LEU A 1 616  ? 220.773 309.286 244.651 1.00 47.06  ? 616  LEU A CA    1 
ATOM   4841  C C     . LEU A 1 616  ? 221.547 308.138 245.289 1.00 47.06  ? 616  LEU A C     1 
ATOM   4842  O O     . LEU A 1 616  ? 221.260 306.965 245.038 1.00 47.06  ? 616  LEU A O     1 
ATOM   4843  C CB    . LEU A 1 616  ? 219.272 309.015 244.637 1.00 47.06  ? 616  LEU A CB    1 
ATOM   4844  C CG    . LEU A 1 616  ? 218.425 309.978 243.803 1.00 47.06  ? 616  LEU A CG    1 
ATOM   4845  C CD1   . LEU A 1 616  ? 216.952 309.608 243.885 1.00 47.06  ? 616  LEU A CD1   1 
ATOM   4846  C CD2   . LEU A 1 616  ? 218.646 311.414 244.252 1.00 47.06  ? 616  LEU A CD2   1 
ATOM   4847  N N     . SER A 1 617  ? 222.532 308.483 246.122 1.00 52.80  ? 617  SER A N     1 
ATOM   4848  C CA    . SER A 1 617  ? 223.330 307.457 246.786 1.00 52.80  ? 617  SER A CA    1 
ATOM   4849  C C     . SER A 1 617  ? 222.558 306.781 247.911 1.00 52.80  ? 617  SER A C     1 
ATOM   4850  O O     . SER A 1 617  ? 222.820 305.615 248.226 1.00 52.80  ? 617  SER A O     1 
ATOM   4851  C CB    . SER A 1 617  ? 224.625 308.066 247.324 1.00 52.80  ? 617  SER A CB    1 
ATOM   4852  O OG    . SER A 1 617  ? 225.205 308.947 246.379 1.00 52.80  ? 617  SER A OG    1 
ATOM   4853  N N     . PHE A 1 618  ? 221.607 307.489 248.523 1.00 50.32  ? 618  PHE A N     1 
ATOM   4854  C CA    . PHE A 1 618  ? 220.849 306.944 249.643 1.00 50.32  ? 618  PHE A CA    1 
ATOM   4855  C C     . PHE A 1 618  ? 219.925 305.805 249.237 1.00 50.32  ? 618  PHE A C     1 
ATOM   4856  O O     . PHE A 1 618  ? 219.495 305.041 250.108 1.00 50.32  ? 618  PHE A O     1 
ATOM   4857  C CB    . PHE A 1 618  ? 220.031 308.055 250.302 1.00 50.32  ? 618  PHE A CB    1 
ATOM   4858  C CG    . PHE A 1 618  ? 218.979 308.645 249.405 1.00 50.32  ? 618  PHE A CG    1 
ATOM   4859  C CD1   . PHE A 1 618  ? 219.291 309.673 248.533 1.00 50.32  ? 618  PHE A CD1   1 
ATOM   4860  C CD2   . PHE A 1 618  ? 217.673 308.183 249.447 1.00 50.32  ? 618  PHE A CD2   1 
ATOM   4861  C CE1   . PHE A 1 618  ? 218.326 310.224 247.715 1.00 50.32  ? 618  PHE A CE1   1 
ATOM   4862  C CE2   . PHE A 1 618  ? 216.703 308.728 248.628 1.00 50.32  ? 618  PHE A CE2   1 
ATOM   4863  C CZ    . PHE A 1 618  ? 217.031 309.750 247.760 1.00 50.32  ? 618  PHE A CZ    1 
ATOM   4864  N N     . MET A 1 619  ? 219.611 305.671 247.951 1.00 55.97  ? 619  MET A N     1 
ATOM   4865  C CA    . MET A 1 619  ? 218.728 304.618 247.470 1.00 55.97  ? 619  MET A CA    1 
ATOM   4866  C C     . MET A 1 619  ? 219.443 303.287 247.286 1.00 55.97  ? 619  MET A C     1 
ATOM   4867  O O     . MET A 1 619  ? 218.788 302.286 246.979 1.00 55.97  ? 619  MET A O     1 
ATOM   4868  C CB    . MET A 1 619  ? 218.075 305.040 246.149 1.00 55.97  ? 619  MET A CB    1 
ATOM   4869  C CG    . MET A 1 619  ? 216.929 306.027 246.307 1.00 55.97  ? 619  MET A CG    1 
ATOM   4870  S SD    . MET A 1 619  ? 215.652 305.449 247.441 1.00 55.97  ? 619  MET A SD    1 
ATOM   4871  C CE    . MET A 1 619  ? 214.694 304.389 246.361 1.00 55.97  ? 619  MET A CE    1 
ATOM   4872  N N     . ASP A 1 620  ? 220.762 303.253 247.461 1.00 72.39  ? 620  ASP A N     1 
ATOM   4873  C CA    . ASP A 1 620  ? 221.510 302.019 247.317 1.00 72.39  ? 620  ASP A CA    1 
ATOM   4874  C C     . ASP A 1 620  ? 221.161 301.049 248.444 1.00 72.39  ? 620  ASP A C     1 
ATOM   4875  O O     . ASP A 1 620  ? 220.901 301.463 249.576 1.00 72.39  ? 620  ASP A O     1 
ATOM   4876  C CB    . ASP A 1 620  ? 223.009 302.308 247.317 1.00 72.39  ? 620  ASP A CB    1 
ATOM   4877  C CG    . ASP A 1 620  ? 223.591 302.370 245.919 1.00 72.39  ? 620  ASP A CG    1 
ATOM   4878  O OD1   . ASP A 1 620  ? 223.519 301.354 245.197 1.00 72.39  ? 620  ASP A OD1   1 
ATOM   4879  O OD2   . ASP A 1 620  ? 224.120 303.437 245.541 1.00 72.39  ? 620  ASP A OD2   1 
ATOM   4880  N N     . PRO A 1 621  ? 221.148 299.739 248.154 1.00 79.26  ? 621  PRO A N     1 
ATOM   4881  C CA    . PRO A 1 621  ? 220.842 298.727 249.171 1.00 79.26  ? 621  PRO A CA    1 
ATOM   4882  C C     . PRO A 1 621  ? 221.947 298.593 250.216 1.00 79.26  ? 621  PRO A C     1 
ATOM   4883  O O     . PRO A 1 621  ? 222.820 297.738 250.065 1.00 79.26  ? 621  PRO A O     1 
ATOM   4884  C CB    . PRO A 1 621  ? 220.702 297.438 248.355 1.00 79.26  ? 621  PRO A CB    1 
ATOM   4885  C CG    . PRO A 1 621  ? 221.499 297.678 247.122 1.00 79.26  ? 621  PRO A CG    1 
ATOM   4886  C CD    . PRO A 1 621  ? 221.390 299.144 246.828 1.00 79.26  ? 621  PRO A CD    1 
ATOM   4887  N N     . ASP A 1 762  ? 166.232 301.224 255.751 1.00 131.38 ? 762  ASP A N     1 
ATOM   4888  C CA    . ASP A 1 762  ? 166.779 299.919 255.397 1.00 131.38 ? 762  ASP A CA    1 
ATOM   4889  C C     . ASP A 1 762  ? 168.016 300.071 254.519 1.00 131.38 ? 762  ASP A C     1 
ATOM   4890  O O     . ASP A 1 762  ? 167.947 300.639 253.428 1.00 131.38 ? 762  ASP A O     1 
ATOM   4891  C CB    . ASP A 1 762  ? 165.724 299.071 254.683 1.00 131.38 ? 762  ASP A CB    1 
ATOM   4892  C CG    . ASP A 1 762  ? 166.198 297.656 254.411 1.00 131.38 ? 762  ASP A CG    1 
ATOM   4893  O OD1   . ASP A 1 762  ? 167.160 297.210 255.071 1.00 131.38 ? 762  ASP A OD1   1 
ATOM   4894  O OD2   . ASP A 1 762  ? 165.607 296.989 253.536 1.00 131.38 ? 762  ASP A OD2   1 
ATOM   4895  N N     . PHE A 1 763  ? 169.150 299.563 255.007 1.00 131.56 ? 763  PHE A N     1 
ATOM   4896  C CA    . PHE A 1 763  ? 170.393 299.656 254.247 1.00 131.56 ? 763  PHE A CA    1 
ATOM   4897  C C     . PHE A 1 763  ? 170.303 298.880 252.938 1.00 131.56 ? 763  PHE A C     1 
ATOM   4898  O O     . PHE A 1 763  ? 170.768 299.354 251.895 1.00 131.56 ? 763  PHE A O     1 
ATOM   4899  C CB    . PHE A 1 763  ? 171.564 299.152 255.091 1.00 131.56 ? 763  PHE A CB    1 
ATOM   4900  C CG    . PHE A 1 763  ? 171.788 299.940 256.349 1.00 131.56 ? 763  PHE A CG    1 
ATOM   4901  C CD1   . PHE A 1 763  ? 172.123 301.283 256.291 1.00 131.56 ? 763  PHE A CD1   1 
ATOM   4902  C CD2   . PHE A 1 763  ? 171.664 299.339 257.591 1.00 131.56 ? 763  PHE A CD2   1 
ATOM   4903  C CE1   . PHE A 1 763  ? 172.330 302.011 257.448 1.00 131.56 ? 763  PHE A CE1   1 
ATOM   4904  C CE2   . PHE A 1 763  ? 171.870 300.061 258.751 1.00 131.56 ? 763  PHE A CE2   1 
ATOM   4905  C CZ    . PHE A 1 763  ? 172.203 301.399 258.679 1.00 131.56 ? 763  PHE A CZ    1 
ATOM   4906  N N     . LYS A 1 764  ? 169.716 297.681 252.975 1.00 128.42 ? 764  LYS A N     1 
ATOM   4907  C CA    . LYS A 1 764  ? 169.603 296.873 251.765 1.00 128.42 ? 764  LYS A CA    1 
ATOM   4908  C C     . LYS A 1 764  ? 168.734 297.560 250.718 1.00 128.42 ? 764  LYS A C     1 
ATOM   4909  O O     . LYS A 1 764  ? 169.071 297.566 249.527 1.00 128.42 ? 764  LYS A O     1 
ATOM   4910  C CB    . LYS A 1 764  ? 169.040 295.493 252.107 1.00 128.42 ? 764  LYS A CB    1 
ATOM   4911  C CG    . LYS A 1 764  ? 169.701 294.832 253.305 1.00 128.42 ? 764  LYS A CG    1 
ATOM   4912  C CD    . LYS A 1 764  ? 169.691 293.318 253.174 1.00 128.42 ? 764  LYS A CD    1 
ATOM   4913  C CE    . LYS A 1 764  ? 170.288 292.655 254.405 1.00 128.42 ? 764  LYS A CE    1 
ATOM   4914  N NZ    . LYS A 1 764  ? 171.340 291.664 254.046 1.00 128.42 ? 764  LYS A NZ    1 
ATOM   4915  N N     . ALA A 1 765  ? 167.609 298.140 251.143 1.00 130.60 ? 765  ALA A N     1 
ATOM   4916  C CA    . ALA A 1 765  ? 166.739 298.843 250.206 1.00 130.60 ? 765  ALA A CA    1 
ATOM   4917  C C     . ALA A 1 765  ? 167.445 300.047 249.595 1.00 130.60 ? 765  ALA A C     1 
ATOM   4918  O O     . ALA A 1 765  ? 167.328 300.299 248.390 1.00 130.60 ? 765  ALA A O     1 
ATOM   4919  C CB    . ALA A 1 765  ? 165.451 299.273 250.906 1.00 130.60 ? 765  ALA A CB    1 
ATOM   4920  N N     . LEU A 1 766  ? 168.181 300.803 250.412 1.00 128.90 ? 766  LEU A N     1 
ATOM   4921  C CA    . LEU A 1 766  ? 168.917 301.953 249.896 1.00 128.90 ? 766  LEU A CA    1 
ATOM   4922  C C     . LEU A 1 766  ? 169.993 301.524 248.906 1.00 128.90 ? 766  LEU A C     1 
ATOM   4923  O O     . LEU A 1 766  ? 170.194 302.177 247.876 1.00 128.90 ? 766  LEU A O     1 
ATOM   4924  C CB    . LEU A 1 766  ? 169.528 302.744 251.053 1.00 128.90 ? 766  LEU A CB    1 
ATOM   4925  C CG    . LEU A 1 766  ? 168.532 303.527 251.912 1.00 128.90 ? 766  LEU A CG    1 
ATOM   4926  C CD1   . LEU A 1 766  ? 169.077 303.749 253.315 1.00 128.90 ? 766  LEU A CD1   1 
ATOM   4927  C CD2   . LEU A 1 766  ? 168.184 304.853 251.254 1.00 128.90 ? 766  LEU A CD2   1 
ATOM   4928  N N     . VAL A 1 767  ? 170.695 300.426 249.201 1.00 128.23 ? 767  VAL A N     1 
ATOM   4929  C CA    . VAL A 1 767  ? 171.721 299.930 248.288 1.00 128.23 ? 767  VAL A CA    1 
ATOM   4930  C C     . VAL A 1 767  ? 171.097 299.488 246.970 1.00 128.23 ? 767  VAL A C     1 
ATOM   4931  O O     . VAL A 1 767  ? 171.624 299.775 245.887 1.00 128.23 ? 767  VAL A O     1 
ATOM   4932  C CB    . VAL A 1 767  ? 172.520 298.792 248.950 1.00 128.23 ? 767  VAL A CB    1 
ATOM   4933  C CG1   . VAL A 1 767  ? 173.343 298.038 247.915 1.00 128.23 ? 767  VAL A CG1   1 
ATOM   4934  C CG2   . VAL A 1 767  ? 173.417 299.346 250.045 1.00 128.23 ? 767  VAL A CG2   1 
ATOM   4935  N N     . LEU A 1 768  ? 169.964 298.783 247.038 1.00 129.72 ? 768  LEU A N     1 
ATOM   4936  C CA    . LEU A 1 768  ? 169.285 298.355 245.818 1.00 129.72 ? 768  LEU A CA    1 
ATOM   4937  C C     . LEU A 1 768  ? 168.819 299.552 244.997 1.00 129.72 ? 768  LEU A C     1 
ATOM   4938  O O     . LEU A 1 768  ? 168.955 299.562 243.767 1.00 129.72 ? 768  LEU A O     1 
ATOM   4939  C CB    . LEU A 1 768  ? 168.104 297.448 246.165 1.00 129.72 ? 768  LEU A CB    1 
ATOM   4940  C CG    . LEU A 1 768  ? 168.447 296.026 246.612 1.00 129.72 ? 768  LEU A CG    1 
ATOM   4941  C CD1   . LEU A 1 768  ? 167.370 295.478 247.535 1.00 129.72 ? 768  LEU A CD1   1 
ATOM   4942  C CD2   . LEU A 1 768  ? 168.639 295.116 245.408 1.00 129.72 ? 768  LEU A CD2   1 
ATOM   4943  N N     . GLN A 1 769  ? 168.267 300.571 245.661 1.00 130.11 ? 769  GLN A N     1 
ATOM   4944  C CA    . GLN A 1 769  ? 167.839 301.772 244.951 1.00 130.11 ? 769  GLN A CA    1 
ATOM   4945  C C     . GLN A 1 769  ? 169.021 302.477 244.298 1.00 130.11 ? 769  GLN A C     1 
ATOM   4946  O O     . GLN A 1 769  ? 168.927 302.922 243.150 1.00 130.11 ? 769  GLN A O     1 
ATOM   4947  C CB    . GLN A 1 769  ? 167.109 302.717 245.906 1.00 130.11 ? 769  GLN A CB    1 
ATOM   4948  C CG    . GLN A 1 769  ? 165.732 302.231 246.328 1.00 130.11 ? 769  GLN A CG    1 
ATOM   4949  C CD    . GLN A 1 769  ? 165.216 302.945 247.562 1.00 130.11 ? 769  GLN A CD    1 
ATOM   4950  O OE1   . GLN A 1 769  ? 165.978 303.258 248.476 1.00 130.11 ? 769  GLN A OE1   1 
ATOM   4951  N NE2   . GLN A 1 769  ? 163.914 303.209 247.592 1.00 130.11 ? 769  GLN A NE2   1 
ATOM   4952  N N     . LEU A 1 770  ? 170.146 302.579 245.012 1.00 125.45 ? 770  LEU A N     1 
ATOM   4953  C CA    . LEU A 1 770  ? 171.342 303.185 244.435 1.00 125.45 ? 770  LEU A CA    1 
ATOM   4954  C C     . LEU A 1 770  ? 171.824 302.407 243.218 1.00 125.45 ? 770  LEU A C     1 
ATOM   4955  O O     . LEU A 1 770  ? 172.241 302.999 242.216 1.00 125.45 ? 770  LEU A O     1 
ATOM   4956  C CB    . LEU A 1 770  ? 172.446 303.269 245.489 1.00 125.45 ? 770  LEU A CB    1 
ATOM   4957  C CG    . LEU A 1 770  ? 173.809 303.791 245.030 1.00 125.45 ? 770  LEU A CG    1 
ATOM   4958  C CD1   . LEU A 1 770  ? 173.726 305.248 244.609 1.00 125.45 ? 770  LEU A CD1   1 
ATOM   4959  C CD2   . LEU A 1 770  ? 174.846 303.607 246.127 1.00 125.45 ? 770  LEU A CD2   1 
ATOM   4960  N N     . LYS A 1 771  ? 171.784 301.075 243.292 1.00 128.39 ? 771  LYS A N     1 
ATOM   4961  C CA    . LYS A 1 771  ? 172.208 300.261 242.158 1.00 128.39 ? 771  LYS A CA    1 
ATOM   4962  C C     . LYS A 1 771  ? 171.277 300.442 240.964 1.00 128.39 ? 771  LYS A C     1 
ATOM   4963  O O     . LYS A 1 771  ? 171.733 300.494 239.816 1.00 128.39 ? 771  LYS A O     1 
ATOM   4964  C CB    . LYS A 1 771  ? 172.277 298.790 242.568 1.00 128.39 ? 771  LYS A CB    1 
ATOM   4965  C CG    . LYS A 1 771  ? 172.858 297.873 241.503 1.00 128.39 ? 771  LYS A CG    1 
ATOM   4966  C CD    . LYS A 1 771  ? 172.971 296.444 242.009 1.00 128.39 ? 771  LYS A CD    1 
ATOM   4967  C CE    . LYS A 1 771  ? 173.550 295.524 240.948 1.00 128.39 ? 771  LYS A CE    1 
ATOM   4968  N NZ    . LYS A 1 771  ? 174.041 294.246 241.533 1.00 128.39 ? 771  LYS A NZ    1 
ATOM   4969  N N     . GLU A 1 772  ? 169.970 300.541 241.212 1.00 128.38 ? 772  GLU A N     1 
ATOM   4970  C CA    . GLU A 1 772  ? 168.993 300.548 240.130 1.00 128.38 ? 772  GLU A CA    1 
ATOM   4971  C C     . GLU A 1 772  ? 168.603 301.941 239.649 1.00 128.38 ? 772  GLU A C     1 
ATOM   4972  O O     . GLU A 1 772  ? 167.926 302.052 238.621 1.00 128.38 ? 772  GLU A O     1 
ATOM   4973  C CB    . GLU A 1 772  ? 167.727 299.800 240.562 1.00 128.38 ? 772  GLU A CB    1 
ATOM   4974  C CG    . GLU A 1 772  ? 167.951 298.333 240.892 1.00 128.38 ? 772  GLU A CG    1 
ATOM   4975  C CD    . GLU A 1 772  ? 166.758 297.704 241.586 1.00 128.38 ? 772  GLU A CD    1 
ATOM   4976  O OE1   . GLU A 1 772  ? 165.802 298.439 241.912 1.00 128.38 ? 772  GLU A OE1   1 
ATOM   4977  O OE2   . GLU A 1 772  ? 166.777 296.474 241.805 1.00 128.38 ? 772  GLU A OE2   1 
ATOM   4978  N N     . THR A 1 773  ? 169.002 303.000 240.351 1.00 125.31 ? 773  THR A N     1 
ATOM   4979  C CA    . THR A 1 773  ? 168.526 304.333 240.002 1.00 125.31 ? 773  THR A CA    1 
ATOM   4980  C C     . THR A 1 773  ? 169.234 304.878 238.765 1.00 125.31 ? 773  THR A C     1 
ATOM   4981  O O     . THR A 1 773  ? 170.418 304.616 238.533 1.00 125.31 ? 773  THR A O     1 
ATOM   4982  C CB    . THR A 1 773  ? 168.710 305.300 241.175 1.00 125.31 ? 773  THR A CB    1 
ATOM   4983  O OG1   . THR A 1 773  ? 168.170 306.582 240.831 1.00 125.31 ? 773  THR A OG1   1 
ATOM   4984  C CG2   . THR A 1 773  ? 170.182 305.452 241.533 1.00 125.31 ? 773  THR A CG2   1 
ATOM   4985  N N     . SER A 1 774  ? 168.484 305.626 237.960 1.00 122.23 ? 774  SER A N     1 
ATOM   4986  C CA    . SER A 1 774  ? 169.024 306.397 236.851 1.00 122.23 ? 774  SER A CA    1 
ATOM   4987  C C     . SER A 1 774  ? 169.331 307.812 237.342 1.00 122.23 ? 774  SER A C     1 
ATOM   4988  O O     . SER A 1 774  ? 169.368 308.073 238.547 1.00 122.23 ? 774  SER A O     1 
ATOM   4989  C CB    . SER A 1 774  ? 168.048 306.388 235.676 1.00 122.23 ? 774  SER A CB    1 
ATOM   4990  O OG    . SER A 1 774  ? 168.278 307.487 234.812 1.00 122.23 ? 774  SER A OG    1 
ATOM   4991  N N     . SER A 1 775  ? 169.561 308.741 236.409 1.00 118.48 ? 775  SER A N     1 
ATOM   4992  C CA    . SER A 1 775  ? 169.791 310.151 236.729 1.00 118.48 ? 775  SER A CA    1 
ATOM   4993  C C     . SER A 1 775  ? 171.019 310.311 237.632 1.00 118.48 ? 775  SER A C     1 
ATOM   4994  O O     . SER A 1 775  ? 170.927 310.633 238.817 1.00 118.48 ? 775  SER A O     1 
ATOM   4995  C CB    . SER A 1 775  ? 168.545 310.781 237.365 1.00 118.48 ? 775  SER A CB    1 
ATOM   4996  O OG    . SER A 1 775  ? 167.364 310.349 236.711 1.00 118.48 ? 775  SER A OG    1 
ATOM   4997  N N     . LEU A 1 776  ? 172.179 310.049 237.022 1.00 110.37 ? 776  LEU A N     1 
ATOM   4998  C CA    . LEU A 1 776  ? 173.478 310.001 237.693 1.00 110.37 ? 776  LEU A CA    1 
ATOM   4999  C C     . LEU A 1 776  ? 173.684 311.099 238.733 1.00 110.37 ? 776  LEU A C     1 
ATOM   5000  O O     . LEU A 1 776  ? 174.374 310.878 239.732 1.00 110.37 ? 776  LEU A O     1 
ATOM   5001  C CB    . LEU A 1 776  ? 174.601 310.064 236.654 1.00 110.37 ? 776  LEU A CB    1 
ATOM   5002  C CG    . LEU A 1 776  ? 175.232 308.727 236.259 1.00 110.37 ? 776  LEU A CG    1 
ATOM   5003  C CD1   . LEU A 1 776  ? 174.233 307.852 235.517 1.00 110.37 ? 776  LEU A CD1   1 
ATOM   5004  C CD2   . LEU A 1 776  ? 176.483 308.949 235.422 1.00 110.37 ? 776  LEU A CD2   1 
ATOM   5005  N N     . GLN A 1 777  ? 173.120 312.289 238.508 1.00 112.38 ? 777  GLN A N     1 
ATOM   5006  C CA    . GLN A 1 777  ? 173.168 313.324 239.538 1.00 112.38 ? 777  GLN A CA    1 
ATOM   5007  C C     . GLN A 1 777  ? 172.429 312.881 240.797 1.00 112.38 ? 777  GLN A C     1 
ATOM   5008  O O     . GLN A 1 777  ? 172.928 313.055 241.918 1.00 112.38 ? 777  GLN A O     1 
ATOM   5009  C CB    . GLN A 1 777  ? 172.580 314.629 238.999 1.00 112.38 ? 777  GLN A CB    1 
ATOM   5010  N N     . GLU A 1 778  ? 171.240 312.297 240.632 1.00 113.67 ? 778  GLU A N     1 
ATOM   5011  C CA    . GLU A 1 778  ? 170.525 311.749 241.780 1.00 113.67 ? 778  GLU A CA    1 
ATOM   5012  C C     . GLU A 1 778  ? 171.290 310.583 242.391 1.00 113.67 ? 778  GLU A C     1 
ATOM   5013  O O     . GLU A 1 778  ? 171.244 310.370 243.607 1.00 113.67 ? 778  GLU A O     1 
ATOM   5014  C CB    . GLU A 1 778  ? 169.117 311.317 241.369 1.00 113.67 ? 778  GLU A CB    1 
ATOM   5015  N N     . GLN A 1 779  ? 172.003 309.816 241.561 1.00 111.60 ? 779  GLN A N     1 
ATOM   5016  C CA    . GLN A 1 779  ? 172.855 308.753 242.083 1.00 111.60 ? 779  GLN A CA    1 
ATOM   5017  C C     . GLN A 1 779  ? 173.947 309.317 242.984 1.00 111.60 ? 779  GLN A C     1 
ATOM   5018  O O     . GLN A 1 779  ? 174.230 308.764 244.054 1.00 111.60 ? 779  GLN A O     1 
ATOM   5019  C CB    . GLN A 1 779  ? 173.469 307.962 240.928 1.00 111.60 ? 779  GLN A CB    1 
ATOM   5020  C CG    . GLN A 1 779  ? 173.670 306.486 241.219 1.00 111.60 ? 779  GLN A CG    1 
ATOM   5021  C CD    . GLN A 1 779  ? 174.201 305.723 240.022 1.00 111.60 ? 779  GLN A CD    1 
ATOM   5022  O OE1   . GLN A 1 779  ? 173.672 305.834 238.916 1.00 111.60 ? 779  GLN A OE1   1 
ATOM   5023  N NE2   . GLN A 1 779  ? 175.254 304.943 240.237 1.00 111.60 ? 779  GLN A NE2   1 
ATOM   5024  N N     . ALA A 1 780  ? 174.572 310.420 242.566 1.00 114.59 ? 780  ALA A N     1 
ATOM   5025  C CA    . ALA A 1 780  ? 175.586 311.063 243.393 1.00 114.59 ? 780  ALA A CA    1 
ATOM   5026  C C     . ALA A 1 780  ? 174.981 311.609 244.680 1.00 114.59 ? 780  ALA A C     1 
ATOM   5027  O O     . ALA A 1 780  ? 175.604 311.533 245.744 1.00 114.59 ? 780  ALA A O     1 
ATOM   5028  C CB    . ALA A 1 780  ? 176.277 312.177 242.609 1.00 114.59 ? 780  ALA A CB    1 
ATOM   5029  N N     . ASP A 1 781  ? 173.773 312.170 244.600 1.00 113.48 ? 781  ASP A N     1 
ATOM   5030  C CA    . ASP A 1 781  ? 173.104 312.658 245.805 1.00 113.48 ? 781  ASP A CA    1 
ATOM   5031  C C     . ASP A 1 781  ? 172.824 311.515 246.778 1.00 113.48 ? 781  ASP A C     1 
ATOM   5032  O O     . ASP A 1 781  ? 173.013 311.652 247.994 1.00 113.48 ? 781  ASP A O     1 
ATOM   5033  C CB    . ASP A 1 781  ? 171.810 313.379 245.427 1.00 113.48 ? 781  ASP A CB    1 
ATOM   5034  C CG    . ASP A 1 781  ? 172.024 314.855 245.150 1.00 113.48 ? 781  ASP A CG    1 
ATOM   5035  O OD1   . ASP A 1 781  ? 172.590 315.551 246.019 1.00 113.48 ? 781  ASP A OD1   1 
ATOM   5036  O OD2   . ASP A 1 781  ? 171.629 315.319 244.059 1.00 113.48 ? 781  ASP A OD2   1 
ATOM   5037  N N     . ILE A 1 782  ? 172.372 310.373 246.254 1.00 112.51 ? 782  ILE A N     1 
ATOM   5038  C CA    . ILE A 1 782  ? 172.128 309.202 247.092 1.00 112.51 ? 782  ILE A CA    1 
ATOM   5039  C C     . ILE A 1 782  ? 173.424 308.732 247.738 1.00 112.51 ? 782  ILE A C     1 
ATOM   5040  O O     . ILE A 1 782  ? 173.476 308.458 248.948 1.00 112.51 ? 782  ILE A O     1 
ATOM   5041  C CB    . ILE A 1 782  ? 171.476 308.081 246.258 1.00 112.51 ? 782  ILE A CB    1 
ATOM   5042  C CG1   . ILE A 1 782  ? 170.059 308.472 245.834 1.00 112.51 ? 782  ILE A CG1   1 
ATOM   5043  C CG2   . ILE A 1 782  ? 171.460 306.769 247.025 1.00 112.51 ? 782  ILE A CG2   1 
ATOM   5044  C CD1   . ILE A 1 782  ? 169.565 307.747 244.599 1.00 112.51 ? 782  ILE A CD1   1 
ATOM   5045  N N     . LEU A 1 783  ? 174.493 308.641 246.942 1.00 110.43 ? 783  LEU A N     1 
ATOM   5046  C CA    . LEU A 1 783  ? 175.781 308.228 247.481 1.00 110.43 ? 783  LEU A CA    1 
ATOM   5047  C C     . LEU A 1 783  ? 176.233 309.176 248.582 1.00 110.43 ? 783  LEU A C     1 
ATOM   5048  O O     . LEU A 1 783  ? 176.748 308.739 249.616 1.00 110.43 ? 783  LEU A O     1 
ATOM   5049  C CB    . LEU A 1 783  ? 176.816 308.165 246.361 1.00 110.43 ? 783  LEU A CB    1 
ATOM   5050  C CG    . LEU A 1 783  ? 177.312 306.772 245.969 1.00 110.43 ? 783  LEU A CG    1 
ATOM   5051  C CD1   . LEU A 1 783  ? 178.318 306.873 244.835 1.00 110.43 ? 783  LEU A CD1   1 
ATOM   5052  C CD2   . LEU A 1 783  ? 177.909 306.053 247.166 1.00 110.43 ? 783  LEU A CD2   1 
ATOM   5053  N N     . TYR A 1 784  ? 176.018 310.479 248.386 1.00 108.18 ? 784  TYR A N     1 
ATOM   5054  C CA    . TYR A 1 784  ? 176.380 311.459 249.403 1.00 108.18 ? 784  TYR A CA    1 
ATOM   5055  C C     . TYR A 1 784  ? 175.575 311.264 250.681 1.00 108.18 ? 784  TYR A C     1 
ATOM   5056  O O     . TYR A 1 784  ? 176.120 311.382 251.785 1.00 108.18 ? 784  TYR A O     1 
ATOM   5057  C CB    . TYR A 1 784  ? 176.181 312.875 248.860 1.00 108.18 ? 784  TYR A CB    1 
ATOM   5058  C CG    . TYR A 1 784  ? 176.325 313.959 249.907 1.00 108.18 ? 784  TYR A CG    1 
ATOM   5059  C CD1   . TYR A 1 784  ? 177.578 314.380 250.335 1.00 108.18 ? 784  TYR A CD1   1 
ATOM   5060  C CD2   . TYR A 1 784  ? 175.206 314.553 250.478 1.00 108.18 ? 784  TYR A CD2   1 
ATOM   5061  C CE1   . TYR A 1 784  ? 177.712 315.368 251.294 1.00 108.18 ? 784  TYR A CE1   1 
ATOM   5062  C CE2   . TYR A 1 784  ? 175.330 315.539 251.440 1.00 108.18 ? 784  TYR A CE2   1 
ATOM   5063  C CZ    . TYR A 1 784  ? 176.585 315.944 251.844 1.00 108.18 ? 784  TYR A CZ    1 
ATOM   5064  O OH    . TYR A 1 784  ? 176.715 316.926 252.800 1.00 108.18 ? 784  TYR A OH    1 
ATOM   5065  N N     . MET A 1 785  ? 174.273 310.984 250.562 1.00 117.62 ? 785  MET A N     1 
ATOM   5066  C CA    . MET A 1 785  ? 173.464 310.904 251.775 1.00 117.62 ? 785  MET A CA    1 
ATOM   5067  C C     . MET A 1 785  ? 173.798 309.645 252.572 1.00 117.62 ? 785  MET A C     1 
ATOM   5068  O O     . MET A 1 785  ? 173.833 309.676 253.809 1.00 117.62 ? 785  MET A O     1 
ATOM   5069  C CB    . MET A 1 785  ? 171.963 310.984 251.470 1.00 117.62 ? 785  MET A CB    1 
ATOM   5070  C CG    . MET A 1 785  ? 171.264 309.710 251.024 1.00 117.62 ? 785  MET A CG    1 
ATOM   5071  S SD    . MET A 1 785  ? 169.645 310.063 250.305 1.00 117.62 ? 785  MET A SD    1 
ATOM   5072  C CE    . MET A 1 785  ? 169.373 308.602 249.315 1.00 117.62 ? 785  MET A CE    1 
ATOM   5073  N N     . LEU A 1 786  ? 174.068 308.525 251.886 1.00 119.49 ? 786  LEU A N     1 
ATOM   5074  C CA    . LEU A 1 786  ? 174.557 307.352 252.616 1.00 119.49 ? 786  LEU A CA    1 
ATOM   5075  C C     . LEU A 1 786  ? 175.966 307.561 253.165 1.00 119.49 ? 786  LEU A C     1 
ATOM   5076  O O     . LEU A 1 786  ? 176.301 307.026 254.229 1.00 119.49 ? 786  LEU A O     1 
ATOM   5077  C CB    . LEU A 1 786  ? 174.483 306.072 251.776 1.00 119.49 ? 786  LEU A CB    1 
ATOM   5078  C CG    . LEU A 1 786  ? 173.165 305.430 251.306 1.00 119.49 ? 786  LEU A CG    1 
ATOM   5079  C CD1   . LEU A 1 786  ? 172.412 304.956 252.540 1.00 119.49 ? 786  LEU A CD1   1 
ATOM   5080  C CD2   . LEU A 1 786  ? 172.254 306.296 250.483 1.00 119.49 ? 786  LEU A CD2   1 
ATOM   5081  N N     . TYR A 1 787  ? 176.808 308.327 252.467 1.00 120.65 ? 787  TYR A N     1 
ATOM   5082  C CA    . TYR A 1 787  ? 178.129 308.635 253.012 1.00 120.65 ? 787  TYR A CA    1 
ATOM   5083  C C     . TYR A 1 787  ? 178.014 309.442 254.298 1.00 120.65 ? 787  TYR A C     1 
ATOM   5084  O O     . TYR A 1 787  ? 178.752 309.202 255.262 1.00 120.65 ? 787  TYR A O     1 
ATOM   5085  C CB    . TYR A 1 787  ? 178.966 309.385 251.972 1.00 120.65 ? 787  TYR A CB    1 
ATOM   5086  C CG    . TYR A 1 787  ? 180.303 309.892 252.480 1.00 120.65 ? 787  TYR A CG    1 
ATOM   5087  C CD1   . TYR A 1 787  ? 180.419 311.156 253.048 1.00 120.65 ? 787  TYR A CD1   1 
ATOM   5088  C CD2   . TYR A 1 787  ? 181.447 309.109 252.389 1.00 120.65 ? 787  TYR A CD2   1 
ATOM   5089  C CE1   . TYR A 1 787  ? 181.633 311.623 253.511 1.00 120.65 ? 787  TYR A CE1   1 
ATOM   5090  C CE2   . TYR A 1 787  ? 182.668 309.569 252.851 1.00 120.65 ? 787  TYR A CE2   1 
ATOM   5091  C CZ    . TYR A 1 787  ? 182.754 310.827 253.410 1.00 120.65 ? 787  TYR A CZ    1 
ATOM   5092  O OH    . TYR A 1 787  ? 183.963 311.292 253.872 1.00 120.65 ? 787  TYR A OH    1 
ATOM   5093  N N     . THR A 1 788  ? 177.095 310.408 254.328 1.00 123.74 ? 788  THR A N     1 
ATOM   5094  C CA    . THR A 1 788  ? 176.920 311.235 255.517 1.00 123.74 ? 788  THR A CA    1 
ATOM   5095  C C     . THR A 1 788  ? 176.215 310.476 256.634 1.00 123.74 ? 788  THR A C     1 
ATOM   5096  O O     . THR A 1 788  ? 176.472 310.736 257.816 1.00 123.74 ? 788  THR A O     1 
ATOM   5097  C CB    . THR A 1 788  ? 176.136 312.500 255.164 1.00 123.74 ? 788  THR A CB    1 
ATOM   5098  O OG1   . THR A 1 788  ? 176.683 313.085 253.975 1.00 123.74 ? 788  THR A OG1   1 
ATOM   5099  C CG2   . THR A 1 788  ? 176.214 313.514 256.296 1.00 123.74 ? 788  THR A CG2   1 
ATOM   5100  N N     . MET A 1 789  ? 175.337 309.533 256.289 1.00 122.23 ? 789  MET A N     1 
ATOM   5101  C CA    . MET A 1 789  ? 174.542 308.832 257.292 1.00 122.23 ? 789  MET A CA    1 
ATOM   5102  C C     . MET A 1 789  ? 175.273 307.615 257.855 1.00 122.23 ? 789  MET A C     1 
ATOM   5103  O O     . MET A 1 789  ? 175.515 307.534 259.063 1.00 122.23 ? 789  MET A O     1 
ATOM   5104  C CB    . MET A 1 789  ? 173.193 308.423 256.691 1.00 122.23 ? 789  MET A CB    1 
ATOM   5105  C CG    . MET A 1 789  ? 172.180 307.932 257.711 1.00 122.23 ? 789  MET A CG    1 
ATOM   5106  S SD    . MET A 1 789  ? 171.979 306.141 257.676 1.00 122.23 ? 789  MET A SD    1 
ATOM   5107  C CE    . MET A 1 789  ? 170.834 305.957 256.312 1.00 122.23 ? 789  MET A CE    1 
ATOM   5108  N N     . LYS A 1 790  ? 175.633 306.659 256.991 1.00 121.97 ? 790  LYS A N     1 
ATOM   5109  C CA    . LYS A 1 790  ? 176.243 305.426 257.476 1.00 121.97 ? 790  LYS A CA    1 
ATOM   5110  C C     . LYS A 1 790  ? 177.336 304.898 256.548 1.00 121.97 ? 790  LYS A C     1 
ATOM   5111  O O     . LYS A 1 790  ? 177.691 303.717 256.636 1.00 121.97 ? 790  LYS A O     1 
ATOM   5112  C CB    . LYS A 1 790  ? 175.170 304.347 257.681 1.00 121.97 ? 790  LYS A CB    1 
ATOM   5113  C CG    . LYS A 1 790  ? 175.487 303.341 258.780 1.00 121.97 ? 790  LYS A CG    1 
ATOM   5114  C CD    . LYS A 1 790  ? 175.302 303.950 260.159 1.00 121.97 ? 790  LYS A CD    1 
ATOM   5115  C CE    . LYS A 1 790  ? 176.451 303.579 261.083 1.00 121.97 ? 790  LYS A CE    1 
ATOM   5116  N NZ    . LYS A 1 790  ? 176.071 303.700 262.518 1.00 121.97 ? 790  LYS A NZ    1 
ATOM   5117  N N     . GLY A 1 791  ? 177.882 305.731 255.665 1.00 125.19 ? 791  GLY A N     1 
ATOM   5118  C CA    . GLY A 1 791  ? 178.898 305.279 254.741 1.00 125.19 ? 791  GLY A CA    1 
ATOM   5119  C C     . GLY A 1 791  ? 180.253 305.969 254.796 1.00 125.19 ? 791  GLY A C     1 
ATOM   5120  O O     . GLY A 1 791  ? 180.818 306.294 253.747 1.00 125.19 ? 791  GLY A O     1 
ATOM   5121  N N     . PRO A 1 792  ? 180.815 306.227 256.003 1.00 127.67 ? 792  PRO A N     1 
ATOM   5122  C CA    . PRO A 1 792  ? 182.157 306.828 256.044 1.00 127.67 ? 792  PRO A CA    1 
ATOM   5123  C C     . PRO A 1 792  ? 183.194 305.905 255.425 1.00 127.67 ? 792  PRO A C     1 
ATOM   5124  O O     . PRO A 1 792  ? 183.937 306.299 254.520 1.00 127.67 ? 792  PRO A O     1 
ATOM   5125  C CB    . PRO A 1 792  ? 182.415 307.038 257.543 1.00 127.67 ? 792  PRO A CB    1 
ATOM   5126  C CG    . PRO A 1 792  ? 181.088 306.893 258.204 1.00 127.67 ? 792  PRO A CG    1 
ATOM   5127  C CD    . PRO A 1 792  ? 180.337 305.919 257.361 1.00 127.67 ? 792  PRO A CD    1 
ATOM   5128  N N     . ASP A 1 793  ? 183.248 304.668 255.919 1.00 130.72 ? 793  ASP A N     1 
ATOM   5129  C CA    . ASP A 1 793  ? 184.109 303.645 255.345 1.00 130.72 ? 793  ASP A CA    1 
ATOM   5130  C C     . ASP A 1 793  ? 183.458 302.269 255.317 1.00 130.72 ? 793  ASP A C     1 
ATOM   5131  O O     . ASP A 1 793  ? 184.116 301.304 254.918 1.00 130.72 ? 793  ASP A O     1 
ATOM   5132  C CB    . ASP A 1 793  ? 185.438 303.569 256.115 1.00 130.72 ? 793  ASP A CB    1 
ATOM   5133  C CG    . ASP A 1 793  ? 186.594 303.117 255.243 1.00 130.72 ? 793  ASP A CG    1 
ATOM   5134  O OD1   . ASP A 1 793  ? 187.238 303.982 254.614 1.00 130.72 ? 793  ASP A OD1   1 
ATOM   5135  O OD2   . ASP A 1 793  ? 186.859 301.898 255.186 1.00 130.72 ? 793  ASP A OD2   1 
ATOM   5136  N N     . TRP A 1 794  ? 182.196 302.148 255.723 1.00 131.46 ? 794  TRP A N     1 
ATOM   5137  C CA    . TRP A 1 794  ? 181.532 300.853 255.758 1.00 131.46 ? 794  TRP A CA    1 
ATOM   5138  C C     . TRP A 1 794  ? 181.259 300.346 254.347 1.00 131.46 ? 794  TRP A C     1 
ATOM   5139  O O     . TRP A 1 794  ? 180.940 301.120 253.440 1.00 131.46 ? 794  TRP A O     1 
ATOM   5140  C CB    . TRP A 1 794  ? 180.224 300.954 256.543 1.00 131.46 ? 794  TRP A CB    1 
ATOM   5141  C CG    . TRP A 1 794  ? 179.426 299.686 256.562 1.00 131.46 ? 794  TRP A CG    1 
ATOM   5142  C CD1   . TRP A 1 794  ? 179.852 298.454 256.965 1.00 131.46 ? 794  TRP A CD1   1 
ATOM   5143  C CD2   . TRP A 1 794  ? 178.058 299.527 256.164 1.00 131.46 ? 794  TRP A CD2   1 
ATOM   5144  N NE1   . TRP A 1 794  ? 178.836 297.537 256.840 1.00 131.46 ? 794  TRP A NE1   1 
ATOM   5145  C CE2   . TRP A 1 794  ? 177.724 298.171 256.351 1.00 131.46 ? 794  TRP A CE2   1 
ATOM   5146  C CE3   . TRP A 1 794  ? 177.085 300.399 255.666 1.00 131.46 ? 794  TRP A CE3   1 
ATOM   5147  C CZ2   . TRP A 1 794  ? 176.459 297.666 256.058 1.00 131.46 ? 794  TRP A CZ2   1 
ATOM   5148  C CZ3   . TRP A 1 794  ? 175.829 299.896 255.376 1.00 131.46 ? 794  TRP A CZ3   1 
ATOM   5149  C CH2   . TRP A 1 794  ? 175.527 298.543 255.573 1.00 131.46 ? 794  TRP A CH2   1 
ATOM   5150  N N     . ASN A 1 795  ? 181.390 299.034 254.167 1.00 131.56 ? 795  ASN A N     1 
ATOM   5151  C CA    . ASN A 1 795  ? 181.123 298.421 252.873 1.00 131.56 ? 795  ASN A CA    1 
ATOM   5152  C C     . ASN A 1 795  ? 179.632 298.479 252.561 1.00 131.56 ? 795  ASN A C     1 
ATOM   5153  O O     . ASN A 1 795  ? 178.795 298.152 253.407 1.00 131.56 ? 795  ASN A O     1 
ATOM   5154  C CB    . ASN A 1 795  ? 181.612 296.973 252.864 1.00 131.56 ? 795  ASN A CB    1 
ATOM   5155  C CG    . ASN A 1 795  ? 181.143 296.204 251.644 1.00 131.56 ? 795  ASN A CG    1 
ATOM   5156  O OD1   . ASN A 1 795  ? 180.647 295.083 251.756 1.00 131.56 ? 795  ASN A OD1   1 
ATOM   5157  N ND2   . ASN A 1 795  ? 181.302 296.801 250.469 1.00 131.56 ? 795  ASN A ND2   1 
ATOM   5158  N N     . THR A 1 796  ? 179.302 298.897 251.339 1.00 135.02 ? 796  THR A N     1 
ATOM   5159  C CA    . THR A 1 796  ? 177.912 298.983 250.912 1.00 135.02 ? 796  THR A CA    1 
ATOM   5160  C C     . THR A 1 796  ? 177.314 297.628 250.558 1.00 135.02 ? 796  THR A C     1 
ATOM   5161  O O     . THR A 1 796  ? 176.090 297.533 250.415 1.00 135.02 ? 796  THR A O     1 
ATOM   5162  C CB    . THR A 1 796  ? 177.785 299.923 249.709 1.00 135.02 ? 796  THR A CB    1 
ATOM   5163  O OG1   . THR A 1 796  ? 178.595 299.437 248.632 1.00 135.02 ? 796  THR A OG1   1 
ATOM   5164  C CG2   . THR A 1 796  ? 178.235 301.328 250.082 1.00 135.02 ? 796  THR A CG2   1 
ATOM   5165  N N     . GLU A 1 797  ? 178.142 296.592 250.409 1.00 137.43 ? 797  GLU A N     1 
ATOM   5166  C CA    . GLU A 1 797  ? 177.687 295.239 250.081 1.00 137.43 ? 797  GLU A CA    1 
ATOM   5167  C C     . GLU A 1 797  ? 176.914 295.202 248.765 1.00 137.43 ? 797  GLU A C     1 
ATOM   5168  O O     . GLU A 1 797  ? 176.027 294.365 248.577 1.00 137.43 ? 797  GLU A O     1 
ATOM   5169  C CB    . GLU A 1 797  ? 176.843 294.643 251.212 1.00 137.43 ? 797  GLU A CB    1 
ATOM   5170  C CG    . GLU A 1 797  ? 177.446 294.811 252.597 1.00 137.43 ? 797  GLU A CG    1 
ATOM   5171  C CD    . GLU A 1 797  ? 176.549 294.269 253.693 1.00 137.43 ? 797  GLU A CD    1 
ATOM   5172  O OE1   . GLU A 1 797  ? 175.312 294.311 253.526 1.00 137.43 ? 797  GLU A OE1   1 
ATOM   5173  O OE2   . GLU A 1 797  ? 177.081 293.802 254.722 1.00 137.43 ? 797  GLU A OE2   1 
ATOM   5174  N N     . LEU A 1 798  ? 177.239 296.115 247.845 1.00 140.35 ? 798  LEU A N     1 
ATOM   5175  C CA    . LEU A 1 798  ? 176.571 296.127 246.548 1.00 140.35 ? 798  LEU A CA    1 
ATOM   5176  C C     . LEU A 1 798  ? 176.898 294.873 245.747 1.00 140.35 ? 798  LEU A C     1 
ATOM   5177  O O     . LEU A 1 798  ? 176.015 294.284 245.113 1.00 140.35 ? 798  LEU A O     1 
ATOM   5178  C CB    . LEU A 1 798  ? 176.961 297.382 245.767 1.00 140.35 ? 798  LEU A CB    1 
ATOM   5179  C CG    . LEU A 1 798  ? 176.131 297.681 244.517 1.00 140.35 ? 798  LEU A CG    1 
ATOM   5180  C CD1   . LEU A 1 798  ? 175.540 299.081 244.586 1.00 140.35 ? 798  LEU A CD1   1 
ATOM   5181  C CD2   . LEU A 1 798  ? 176.968 297.511 243.259 1.00 140.35 ? 798  LEU A CD2   1 
ATOM   5182  N N     . TYR A 1 799  ? 178.157 294.451 245.764 1.00 145.32 ? 799  TYR A N     1 
ATOM   5183  C CA    . TYR A 1 799  ? 178.597 293.256 245.061 1.00 145.32 ? 799  TYR A CA    1 
ATOM   5184  C C     . TYR A 1 799  ? 178.653 292.068 246.015 1.00 145.32 ? 799  TYR A C     1 
ATOM   5185  O O     . TYR A 1 799  ? 178.737 292.222 247.236 1.00 145.32 ? 799  TYR A O     1 
ATOM   5186  C CB    . TYR A 1 799  ? 179.969 293.476 244.418 1.00 145.32 ? 799  TYR A CB    1 
ATOM   5187  C CG    . TYR A 1 799  ? 180.034 294.675 243.498 1.00 145.32 ? 799  TYR A CG    1 
ATOM   5188  C CD1   . TYR A 1 799  ? 179.655 294.575 242.166 1.00 145.32 ? 799  TYR A CD1   1 
ATOM   5189  C CD2   . TYR A 1 799  ? 180.480 295.907 243.961 1.00 145.32 ? 799  TYR A CD2   1 
ATOM   5190  C CE1   . TYR A 1 799  ? 179.715 295.668 241.321 1.00 145.32 ? 799  TYR A CE1   1 
ATOM   5191  C CE2   . TYR A 1 799  ? 180.544 297.005 243.124 1.00 145.32 ? 799  TYR A CE2   1 
ATOM   5192  C CZ    . TYR A 1 799  ? 180.160 296.880 241.806 1.00 145.32 ? 799  TYR A CZ    1 
ATOM   5193  O OH    . TYR A 1 799  ? 180.221 297.970 240.969 1.00 145.32 ? 799  TYR A OH    1 
ATOM   5194  N N     . ASN A 1 800  ? 178.604 290.870 245.435 1.00 150.44 ? 800  ASN A N     1 
ATOM   5195  C CA    . ASN A 1 800  ? 178.634 289.628 246.199 1.00 150.44 ? 800  ASN A CA    1 
ATOM   5196  C C     . ASN A 1 800  ? 179.979 288.916 246.108 1.00 150.44 ? 800  ASN A C     1 
ATOM   5197  O O     . ASN A 1 800  ? 180.494 288.436 247.121 1.00 150.44 ? 800  ASN A O     1 
ATOM   5198  C CB    . ASN A 1 800  ? 177.516 288.692 245.723 1.00 150.44 ? 800  ASN A CB    1 
ATOM   5199  C CG    . ASN A 1 800  ? 176.135 289.284 245.927 1.00 150.44 ? 800  ASN A CG    1 
ATOM   5200  O OD1   . ASN A 1 800  ? 175.913 290.470 245.683 1.00 150.44 ? 800  ASN A OD1   1 
ATOM   5201  N ND2   . ASN A 1 800  ? 175.197 288.458 246.376 1.00 150.44 ? 800  ASN A ND2   1 
ATOM   5202  N N     . GLU A 1 801  ? 180.554 288.833 244.905 1.00 149.81 ? 801  GLU A N     1 
ATOM   5203  C CA    . GLU A 1 801  ? 181.831 288.145 244.741 1.00 149.81 ? 801  GLU A CA    1 
ATOM   5204  C C     . GLU A 1 801  ? 182.950 288.860 245.489 1.00 149.81 ? 801  GLU A C     1 
ATOM   5205  O O     . GLU A 1 801  ? 183.781 288.217 246.140 1.00 149.81 ? 801  GLU A O     1 
ATOM   5206  C CB    . GLU A 1 801  ? 182.173 288.023 243.256 1.00 149.81 ? 801  GLU A CB    1 
ATOM   5207  C CG    . GLU A 1 801  ? 181.527 286.832 242.566 1.00 149.81 ? 801  GLU A CG    1 
ATOM   5208  C CD    . GLU A 1 801  ? 182.079 286.596 241.174 1.00 149.81 ? 801  GLU A CD    1 
ATOM   5209  O OE1   . GLU A 1 801  ? 182.765 287.496 240.645 1.00 149.81 ? 801  GLU A OE1   1 
ATOM   5210  O OE2   . GLU A 1 801  ? 181.826 285.511 240.609 1.00 149.81 ? 801  GLU A OE2   1 
ATOM   5211  N N     . ARG A 1 802  ? 182.988 290.188 245.409 1.00 146.39 ? 802  ARG A N     1 
ATOM   5212  C CA    . ARG A 1 802  ? 184.020 290.984 246.057 1.00 146.39 ? 802  ARG A CA    1 
ATOM   5213  C C     . ARG A 1 802  ? 183.376 292.089 246.878 1.00 146.39 ? 802  ARG A C     1 
ATOM   5214  O O     . ARG A 1 802  ? 182.397 292.706 246.447 1.00 146.39 ? 802  ARG A O     1 
ATOM   5215  C CB    . ARG A 1 802  ? 184.985 291.591 245.031 1.00 146.39 ? 802  ARG A CB    1 
ATOM   5216  C CG    . ARG A 1 802  ? 185.788 290.566 244.247 1.00 146.39 ? 802  ARG A CG    1 
ATOM   5217  C CD    . ARG A 1 802  ? 186.725 291.238 243.257 1.00 146.39 ? 802  ARG A CD    1 
ATOM   5218  N NE    . ARG A 1 802  ? 187.625 290.284 242.621 1.00 146.39 ? 802  ARG A NE    1 
ATOM   5219  C CZ    . ARG A 1 802  ? 188.564 290.611 241.743 1.00 146.39 ? 802  ARG A CZ    1 
ATOM   5220  N NH1   . ARG A 1 802  ? 188.756 291.866 241.372 1.00 146.39 ? 802  ARG A NH1   1 
ATOM   5221  N NH2   . ARG A 1 802  ? 189.329 289.654 241.226 1.00 146.39 ? 802  ARG A NH2   1 
ATOM   5222  N N     . SER A 1 803  ? 183.930 292.335 248.063 1.00 138.48 ? 803  SER A N     1 
ATOM   5223  C CA    . SER A 1 803  ? 183.442 293.385 248.951 1.00 138.48 ? 803  SER A CA    1 
ATOM   5224  C C     . SER A 1 803  ? 184.204 294.670 248.649 1.00 138.48 ? 803  SER A C     1 
ATOM   5225  O O     . SER A 1 803  ? 185.396 294.782 248.954 1.00 138.48 ? 803  SER A O     1 
ATOM   5226  C CB    . SER A 1 803  ? 183.609 292.976 250.412 1.00 138.48 ? 803  SER A CB    1 
ATOM   5227  O OG    . SER A 1 803  ? 183.441 294.086 251.276 1.00 138.48 ? 803  SER A OG    1 
ATOM   5228  N N     . ALA A 1 804  ? 183.517 295.639 248.050 1.00 127.03 ? 804  ALA A N     1 
ATOM   5229  C CA    . ALA A 1 804  ? 184.106 296.920 247.687 1.00 127.03 ? 804  ALA A CA    1 
ATOM   5230  C C     . ALA A 1 804  ? 183.587 297.999 248.626 1.00 127.03 ? 804  ALA A C     1 
ATOM   5231  O O     . ALA A 1 804  ? 182.374 298.126 248.824 1.00 127.03 ? 804  ALA A O     1 
ATOM   5232  C CB    . ALA A 1 804  ? 183.785 297.281 246.235 1.00 127.03 ? 804  ALA A CB    1 
ATOM   5233  N N     . THR A 1 805  ? 184.506 298.773 249.199 1.00 118.14 ? 805  THR A N     1 
ATOM   5234  C CA    . THR A 1 805  ? 184.127 299.826 250.127 1.00 118.14 ? 805  THR A CA    1 
ATOM   5235  C C     . THR A 1 805  ? 183.504 301.003 249.377 1.00 118.14 ? 805  THR A C     1 
ATOM   5236  O O     . THR A 1 805  ? 183.413 301.021 248.146 1.00 118.14 ? 805  THR A O     1 
ATOM   5237  C CB    . THR A 1 805  ? 185.338 300.295 250.933 1.00 118.14 ? 805  THR A CB    1 
ATOM   5238  O OG1   . THR A 1 805  ? 186.414 300.614 250.042 1.00 118.14 ? 805  THR A OG1   1 
ATOM   5239  C CG2   . THR A 1 805  ? 185.790 299.206 251.896 1.00 118.14 ? 805  THR A CG2   1 
ATOM   5240  N N     . VAL A 1 806  ? 183.065 302.001 250.147 1.00 113.49 ? 806  VAL A N     1 
ATOM   5241  C CA    . VAL A 1 806  ? 182.443 303.181 249.554 1.00 113.49 ? 806  VAL A CA    1 
ATOM   5242  C C     . VAL A 1 806  ? 183.464 303.977 248.748 1.00 113.49 ? 806  VAL A C     1 
ATOM   5243  O O     . VAL A 1 806  ? 183.123 304.609 247.741 1.00 113.49 ? 806  VAL A O     1 
ATOM   5244  C CB    . VAL A 1 806  ? 181.770 304.038 250.645 1.00 113.49 ? 806  VAL A CB    1 
ATOM   5245  C CG1   . VAL A 1 806  ? 182.803 304.610 251.608 1.00 113.49 ? 806  VAL A CG1   1 
ATOM   5246  C CG2   . VAL A 1 806  ? 180.938 305.149 250.017 1.00 113.49 ? 806  VAL A CG2   1 
ATOM   5247  N N     . ARG A 1 807  ? 184.730 303.960 249.175 1.00 112.43 ? 807  ARG A N     1 
ATOM   5248  C CA    . ARG A 1 807  ? 185.764 304.701 248.459 1.00 112.43 ? 807  ARG A CA    1 
ATOM   5249  C C     . ARG A 1 807  ? 185.994 304.131 247.064 1.00 112.43 ? 807  ARG A C     1 
ATOM   5250  O O     . ARG A 1 807  ? 186.185 304.884 246.102 1.00 112.43 ? 807  ARG A O     1 
ATOM   5251  C CB    . ARG A 1 807  ? 187.064 304.697 249.264 1.00 112.43 ? 807  ARG A CB    1 
ATOM   5252  C CG    . ARG A 1 807  ? 187.858 305.991 249.168 1.00 112.43 ? 807  ARG A CG    1 
ATOM   5253  C CD    . ARG A 1 807  ? 187.066 307.175 249.705 1.00 112.43 ? 807  ARG A CD    1 
ATOM   5254  N NE    . ARG A 1 807  ? 186.352 306.851 250.935 1.00 112.43 ? 807  ARG A NE    1 
ATOM   5255  C CZ    . ARG A 1 807  ? 186.889 306.888 252.146 1.00 112.43 ? 807  ARG A CZ    1 
ATOM   5256  N NH1   . ARG A 1 807  ? 188.153 307.234 252.332 1.00 112.43 ? 807  ARG A NH1   1 
ATOM   5257  N NH2   . ARG A 1 807  ? 186.140 306.571 253.198 1.00 112.43 ? 807  ARG A NH2   1 
ATOM   5258  N N     . GLU A 1 808  ? 185.991 302.801 246.935 1.00 112.37 ? 808  GLU A N     1 
ATOM   5259  C CA    . GLU A 1 808  ? 186.172 302.186 245.624 1.00 112.37 ? 808  GLU A CA    1 
ATOM   5260  C C     . GLU A 1 808  ? 185.029 302.546 244.682 1.00 112.37 ? 808  GLU A C     1 
ATOM   5261  O O     . GLU A 1 808  ? 185.257 302.860 243.507 1.00 112.37 ? 808  GLU A O     1 
ATOM   5262  C CB    . GLU A 1 808  ? 186.294 300.669 245.767 1.00 112.37 ? 808  GLU A CB    1 
ATOM   5263  C CG    . GLU A 1 808  ? 187.711 300.180 246.018 1.00 112.37 ? 808  GLU A CG    1 
ATOM   5264  C CD    . GLU A 1 808  ? 188.197 300.494 247.420 1.00 112.37 ? 808  GLU A CD    1 
ATOM   5265  O OE1   . GLU A 1 808  ? 187.782 299.792 248.365 1.00 112.37 ? 808  GLU A OE1   1 
ATOM   5266  O OE2   . GLU A 1 808  ? 188.995 301.443 247.575 1.00 112.37 ? 808  GLU A OE2   1 
ATOM   5267  N N     . LEU A 1 809  ? 183.791 302.508 245.181 1.00 107.02 ? 809  LEU A N     1 
ATOM   5268  C CA    . LEU A 1 809  ? 182.650 302.889 244.356 1.00 107.02 ? 809  LEU A CA    1 
ATOM   5269  C C     . LEU A 1 809  ? 182.713 304.365 243.984 1.00 107.02 ? 809  LEU A C     1 
ATOM   5270  O O     . LEU A 1 809  ? 182.361 304.744 242.861 1.00 107.02 ? 809  LEU A O     1 
ATOM   5271  C CB    . LEU A 1 809  ? 181.346 302.564 245.089 1.00 107.02 ? 809  LEU A CB    1 
ATOM   5272  C CG    . LEU A 1 809  ? 180.088 302.288 244.258 1.00 107.02 ? 809  LEU A CG    1 
ATOM   5273  C CD1   . LEU A 1 809  ? 179.082 301.495 245.078 1.00 107.02 ? 809  LEU A CD1   1 
ATOM   5274  C CD2   . LEU A 1 809  ? 179.452 303.571 243.745 1.00 107.02 ? 809  LEU A CD2   1 
ATOM   5275  N N     . LEU A 1 810  ? 183.160 305.213 244.915 1.00 100.96 ? 810  LEU A N     1 
ATOM   5276  C CA    . LEU A 1 810  ? 183.303 306.634 244.619 1.00 100.96 ? 810  LEU A CA    1 
ATOM   5277  C C     . LEU A 1 810  ? 184.335 306.862 243.521 1.00 100.96 ? 810  LEU A C     1 
ATOM   5278  O O     . LEU A 1 810  ? 184.120 307.669 242.608 1.00 100.96 ? 810  LEU A O     1 
ATOM   5279  C CB    . LEU A 1 810  ? 183.695 307.392 245.887 1.00 100.96 ? 810  LEU A CB    1 
ATOM   5280  C CG    . LEU A 1 810  ? 182.603 308.182 246.615 1.00 100.96 ? 810  LEU A CG    1 
ATOM   5281  C CD1   . LEU A 1 810  ? 182.290 309.485 245.902 1.00 100.96 ? 810  LEU A CD1   1 
ATOM   5282  C CD2   . LEU A 1 810  ? 181.349 307.341 246.787 1.00 100.96 ? 810  LEU A CD2   1 
ATOM   5283  N N     . THR A 1 811  ? 185.465 306.154 243.595 1.00 99.27  ? 811  THR A N     1 
ATOM   5284  C CA    . THR A 1 811  ? 186.491 306.276 242.563 1.00 99.27  ? 811  THR A CA    1 
ATOM   5285  C C     . THR A 1 811  ? 185.985 305.767 241.219 1.00 99.27  ? 811  THR A C     1 
ATOM   5286  O O     . THR A 1 811  ? 186.281 306.356 240.172 1.00 99.27  ? 811  THR A O     1 
ATOM   5287  C CB    . THR A 1 811  ? 187.752 305.520 242.982 1.00 99.27  ? 811  THR A CB    1 
ATOM   5288  O OG1   . THR A 1 811  ? 188.055 305.813 244.351 1.00 99.27  ? 811  THR A OG1   1 
ATOM   5289  C CG2   . THR A 1 811  ? 188.931 305.926 242.110 1.00 99.27  ? 811  THR A CG2   1 
ATOM   5290  N N     . GLU A 1 812  ? 185.226 304.668 241.227 1.00 102.38 ? 812  GLU A N     1 
ATOM   5291  C CA    . GLU A 1 812  ? 184.650 304.158 239.986 1.00 102.38 ? 812  GLU A CA    1 
ATOM   5292  C C     . GLU A 1 812  ? 183.682 305.163 239.376 1.00 102.38 ? 812  GLU A C     1 
ATOM   5293  O O     . GLU A 1 812  ? 183.680 305.377 238.157 1.00 102.38 ? 812  GLU A O     1 
ATOM   5294  C CB    . GLU A 1 812  ? 183.951 302.822 240.244 1.00 102.38 ? 812  GLU A CB    1 
ATOM   5295  C CG    . GLU A 1 812  ? 182.955 302.418 239.168 1.00 102.38 ? 812  GLU A CG    1 
ATOM   5296  C CD    . GLU A 1 812  ? 182.625 300.939 239.206 1.00 102.38 ? 812  GLU A CD    1 
ATOM   5297  O OE1   . GLU A 1 812  ? 182.128 300.466 240.249 1.00 102.38 ? 812  GLU A OE1   1 
ATOM   5298  O OE2   . GLU A 1 812  ? 182.863 300.250 238.192 1.00 102.38 ? 812  GLU A OE2   1 
ATOM   5299  N N     . LEU A 1 813  ? 182.849 305.791 240.210 1.00 92.25  ? 813  LEU A N     1 
ATOM   5300  C CA    . LEU A 1 813  ? 181.929 306.810 239.716 1.00 92.25  ? 813  LEU A CA    1 
ATOM   5301  C C     . LEU A 1 813  ? 182.684 308.005 239.148 1.00 92.25  ? 813  LEU A C     1 
ATOM   5302  O O     . LEU A 1 813  ? 182.303 308.551 238.107 1.00 92.25  ? 813  LEU A O     1 
ATOM   5303  C CB    . LEU A 1 813  ? 180.985 307.253 240.834 1.00 92.25  ? 813  LEU A CB    1 
ATOM   5304  C CG    . LEU A 1 813  ? 179.605 307.746 240.395 1.00 92.25  ? 813  LEU A CG    1 
ATOM   5305  C CD1   . LEU A 1 813  ? 178.698 306.574 240.054 1.00 92.25  ? 813  LEU A CD1   1 
ATOM   5306  C CD2   . LEU A 1 813  ? 178.978 308.618 241.473 1.00 92.25  ? 813  LEU A CD2   1 
ATOM   5307  N N     . TYR A 1 814  ? 183.757 308.429 239.822 1.00 86.02  ? 814  TYR A N     1 
ATOM   5308  C CA    . TYR A 1 814  ? 184.564 309.533 239.310 1.00 86.02  ? 814  TYR A CA    1 
ATOM   5309  C C     . TYR A 1 814  ? 185.177 309.182 237.960 1.00 86.02  ? 814  TYR A C     1 
ATOM   5310  O O     . TYR A 1 814  ? 185.180 310.005 237.036 1.00 86.02  ? 814  TYR A O     1 
ATOM   5311  C CB    . TYR A 1 814  ? 185.646 309.903 240.332 1.00 86.02  ? 814  TYR A CB    1 
ATOM   5312  C CG    . TYR A 1 814  ? 186.640 310.961 239.883 1.00 86.02  ? 814  TYR A CG    1 
ATOM   5313  C CD1   . TYR A 1 814  ? 187.704 310.644 239.044 1.00 86.02  ? 814  TYR A CD1   1 
ATOM   5314  C CD2   . TYR A 1 814  ? 186.512 312.278 240.302 1.00 86.02  ? 814  TYR A CD2   1 
ATOM   5315  C CE1   . TYR A 1 814  ? 188.608 311.608 238.638 1.00 86.02  ? 814  TYR A CE1   1 
ATOM   5316  C CE2   . TYR A 1 814  ? 187.411 313.249 239.900 1.00 86.02  ? 814  TYR A CE2   1 
ATOM   5317  C CZ    . TYR A 1 814  ? 188.456 312.908 239.069 1.00 86.02  ? 814  TYR A CZ    1 
ATOM   5318  O OH    . TYR A 1 814  ? 189.354 313.870 238.666 1.00 86.02  ? 814  TYR A OH    1 
ATOM   5319  N N     . GLY A 1 815  ? 185.702 307.962 237.828 1.00 89.10  ? 815  GLY A N     1 
ATOM   5320  C CA    . GLY A 1 815  ? 186.269 307.544 236.557 1.00 89.10  ? 815  GLY A CA    1 
ATOM   5321  C C     . GLY A 1 815  ? 185.238 307.484 235.447 1.00 89.10  ? 815  GLY A C     1 
ATOM   5322  O O     . GLY A 1 815  ? 185.512 307.875 234.310 1.00 89.10  ? 815  GLY A O     1 
ATOM   5323  N N     . LYS A 1 816  ? 184.038 306.987 235.761 1.00 89.05  ? 816  LYS A N     1 
ATOM   5324  C CA    . LYS A 1 816  ? 182.972 306.944 234.765 1.00 89.05  ? 816  LYS A CA    1 
ATOM   5325  C C     . LYS A 1 816  ? 182.552 308.347 234.344 1.00 89.05  ? 816  LYS A C     1 
ATOM   5326  O O     . LYS A 1 816  ? 182.321 308.605 233.157 1.00 89.05  ? 816  LYS A O     1 
ATOM   5327  C CB    . LYS A 1 816  ? 181.776 306.164 235.313 1.00 89.05  ? 816  LYS A CB    1 
ATOM   5328  C CG    . LYS A 1 816  ? 180.488 306.364 234.531 1.00 89.05  ? 816  LYS A CG    1 
ATOM   5329  C CD    . LYS A 1 816  ? 179.461 305.297 234.874 1.00 89.05  ? 816  LYS A CD    1 
ATOM   5330  C CE    . LYS A 1 816  ? 178.219 305.423 234.005 1.00 89.05  ? 816  LYS A CE    1 
ATOM   5331  N NZ    . LYS A 1 816  ? 178.204 306.694 233.229 1.00 89.05  ? 816  LYS A NZ    1 
ATOM   5332  N N     . VAL A 1 817  ? 182.450 309.269 235.305 1.00 84.16  ? 817  VAL A N     1 
ATOM   5333  C CA    . VAL A 1 817  ? 182.054 310.638 234.991 1.00 84.16  ? 817  VAL A CA    1 
ATOM   5334  C C     . VAL A 1 817  ? 183.126 311.339 234.165 1.00 84.16  ? 817  VAL A C     1 
ATOM   5335  O O     . VAL A 1 817  ? 182.809 312.130 233.268 1.00 84.16  ? 817  VAL A O     1 
ATOM   5336  C CB    . VAL A 1 817  ? 181.739 311.406 236.288 1.00 84.16  ? 817  VAL A CB    1 
ATOM   5337  C CG1   . VAL A 1 817  ? 181.613 312.895 236.016 1.00 84.16  ? 817  VAL A CG1   1 
ATOM   5338  C CG2   . VAL A 1 817  ? 180.462 310.873 236.918 1.00 84.16  ? 817  VAL A CG2   1 
ATOM   5339  N N     . GLY A 1 818  ? 184.403 311.060 234.436 1.00 85.80  ? 818  GLY A N     1 
ATOM   5340  C CA    . GLY A 1 818  ? 185.474 311.698 233.691 1.00 85.80  ? 818  GLY A CA    1 
ATOM   5341  C C     . GLY A 1 818  ? 185.444 311.421 232.202 1.00 85.80  ? 818  GLY A C     1 
ATOM   5342  O O     . GLY A 1 818  ? 185.924 312.246 231.417 1.00 85.80  ? 818  GLY A O     1 
ATOM   5343  N N     . GLU A 1 819  ? 184.891 310.277 231.793 1.00 95.13  ? 819  GLU A N     1 
ATOM   5344  C CA    . GLU A 1 819  ? 184.804 309.957 230.373 1.00 95.13  ? 819  GLU A CA    1 
ATOM   5345  C C     . GLU A 1 819  ? 183.718 310.772 229.678 1.00 95.13  ? 819  GLU A C     1 
ATOM   5346  O O     . GLU A 1 819  ? 183.914 311.247 228.554 1.00 95.13  ? 819  GLU A O     1 
ATOM   5347  C CB    . GLU A 1 819  ? 184.552 308.459 230.188 1.00 95.13  ? 819  GLU A CB    1 
ATOM   5348  C CG    . GLU A 1 819  ? 185.685 307.575 230.680 1.00 95.13  ? 819  GLU A CG    1 
ATOM   5349  C CD    . GLU A 1 819  ? 186.921 307.676 229.808 1.00 95.13  ? 819  GLU A CD    1 
ATOM   5350  O OE1   . GLU A 1 819  ? 186.772 307.810 228.575 1.00 95.13  ? 819  GLU A OE1   1 
ATOM   5351  O OE2   . GLU A 1 819  ? 188.043 307.622 230.355 1.00 95.13  ? 819  GLU A OE2   1 
ATOM   5352  N N     . ILE A 1 820  ? 182.566 310.944 230.331 1.00 85.92  ? 820  ILE A N     1 
ATOM   5353  C CA    . ILE A 1 820  ? 181.463 311.658 229.694 1.00 85.92  ? 820  ILE A CA    1 
ATOM   5354  C C     . ILE A 1 820  ? 181.722 313.160 229.681 1.00 85.92  ? 820  ILE A C     1 
ATOM   5355  O O     . ILE A 1 820  ? 181.135 313.889 228.871 1.00 85.92  ? 820  ILE A O     1 
ATOM   5356  C CB    . ILE A 1 820  ? 180.130 311.313 230.387 1.00 85.92  ? 820  ILE A CB    1 
ATOM   5357  C CG1   . ILE A 1 820  ? 178.947 311.677 229.487 1.00 85.92  ? 820  ILE A CG1   1 
ATOM   5358  C CG2   . ILE A 1 820  ? 180.013 312.024 231.726 1.00 85.92  ? 820  ILE A CG2   1 
ATOM   5359  C CD1   . ILE A 1 820  ? 178.474 310.538 228.609 1.00 85.92  ? 820  ILE A CD1   1 
ATOM   5360  N N     . ARG A 1 821  ? 182.600 313.646 230.562 1.00 81.99  ? 821  ARG A N     1 
ATOM   5361  C CA    . ARG A 1 821  ? 182.978 315.058 230.630 1.00 81.99  ? 821  ARG A CA    1 
ATOM   5362  C C     . ARG A 1 821  ? 181.752 315.950 230.846 1.00 81.99  ? 821  ARG A C     1 
ATOM   5363  O O     . ARG A 1 821  ? 181.435 316.832 230.045 1.00 81.99  ? 821  ARG A O     1 
ATOM   5364  C CB    . ARG A 1 821  ? 183.754 315.477 229.376 1.00 81.99  ? 821  ARG A CB    1 
ATOM   5365  C CG    . ARG A 1 821  ? 184.975 314.621 229.087 1.00 81.99  ? 821  ARG A CG    1 
ATOM   5366  C CD    . ARG A 1 821  ? 185.900 315.302 228.092 1.00 81.99  ? 821  ARG A CD    1 
ATOM   5367  N NE    . ARG A 1 821  ? 186.457 316.541 228.621 1.00 81.99  ? 821  ARG A NE    1 
ATOM   5368  C CZ    . ARG A 1 821  ? 187.432 316.606 229.518 1.00 81.99  ? 821  ARG A CZ    1 
ATOM   5369  N NH1   . ARG A 1 821  ? 187.996 315.513 230.006 1.00 81.99  ? 821  ARG A NH1   1 
ATOM   5370  N NH2   . ARG A 1 821  ? 187.853 317.797 229.933 1.00 81.99  ? 821  ARG A NH2   1 
ATOM   5371  N N     . HIS A 1 822  ? 181.062 315.700 231.958 1.00 79.78  ? 822  HIS A N     1 
ATOM   5372  C CA    . HIS A 1 822  ? 179.862 316.444 232.330 1.00 79.78  ? 822  HIS A CA    1 
ATOM   5373  C C     . HIS A 1 822  ? 180.076 317.003 233.731 1.00 79.78  ? 822  HIS A C     1 
ATOM   5374  O O     . HIS A 1 822  ? 180.209 316.240 234.695 1.00 79.78  ? 822  HIS A O     1 
ATOM   5375  C CB    . HIS A 1 822  ? 178.622 315.547 232.241 1.00 79.78  ? 822  HIS A CB    1 
ATOM   5376  C CG    . HIS A 1 822  ? 177.528 315.896 233.204 1.00 79.78  ? 822  HIS A CG    1 
ATOM   5377  N ND1   . HIS A 1 822  ? 177.601 315.625 234.553 1.00 79.78  ? 822  HIS A ND1   1 
ATOM   5378  C CD2   . HIS A 1 822  ? 176.326 316.488 233.005 1.00 79.78  ? 822  HIS A CD2   1 
ATOM   5379  C CE1   . HIS A 1 822  ? 176.492 316.034 235.143 1.00 79.78  ? 822  HIS A CE1   1 
ATOM   5380  N NE2   . HIS A 1 822  ? 175.704 316.565 234.227 1.00 79.78  ? 822  HIS A NE2   1 
ATOM   5381  N N     . TRP A 1 823  ? 180.112 318.328 233.841 1.00 70.98  ? 823  TRP A N     1 
ATOM   5382  C CA    . TRP A 1 823  ? 180.490 319.012 235.080 1.00 70.98  ? 823  TRP A CA    1 
ATOM   5383  C C     . TRP A 1 823  ? 179.281 319.332 235.955 1.00 70.98  ? 823  TRP A C     1 
ATOM   5384  O O     . TRP A 1 823  ? 179.064 320.477 236.349 1.00 70.98  ? 823  TRP A O     1 
ATOM   5385  C CB    . TRP A 1 823  ? 181.270 320.280 234.751 1.00 70.98  ? 823  TRP A CB    1 
ATOM   5386  C CG    . TRP A 1 823  ? 182.356 320.089 233.733 1.00 70.98  ? 823  TRP A CG    1 
ATOM   5387  C CD1   . TRP A 1 823  ? 182.213 320.061 232.375 1.00 70.98  ? 823  TRP A CD1   1 
ATOM   5388  C CD2   . TRP A 1 823  ? 183.755 319.917 233.992 1.00 70.98  ? 823  TRP A CD2   1 
ATOM   5389  N NE1   . TRP A 1 823  ? 183.434 319.873 231.774 1.00 70.98  ? 823  TRP A NE1   1 
ATOM   5390  C CE2   . TRP A 1 823  ? 184.397 319.782 232.745 1.00 70.98  ? 823  TRP A CE2   1 
ATOM   5391  C CE3   . TRP A 1 823  ? 184.526 319.861 235.157 1.00 70.98  ? 823  TRP A CE3   1 
ATOM   5392  C CZ2   . TRP A 1 823  ? 185.773 319.594 232.630 1.00 70.98  ? 823  TRP A CZ2   1 
ATOM   5393  C CZ3   . TRP A 1 823  ? 185.891 319.673 235.041 1.00 70.98  ? 823  TRP A CZ3   1 
ATOM   5394  C CH2   . TRP A 1 823  ? 186.501 319.542 233.787 1.00 70.98  ? 823  TRP A CH2   1 
ATOM   5395  N N     . GLY A 1 824  ? 178.483 318.318 236.276 1.00 76.81  ? 824  GLY A N     1 
ATOM   5396  C CA    . GLY A 1 824  ? 177.348 318.518 237.156 1.00 76.81  ? 824  GLY A CA    1 
ATOM   5397  C C     . GLY A 1 824  ? 177.558 317.926 238.533 1.00 76.81  ? 824  GLY A C     1 
ATOM   5398  O O     . GLY A 1 824  ? 177.138 318.505 239.540 1.00 76.81  ? 824  GLY A O     1 
ATOM   5399  N N     . LEU A 1 825  ? 178.209 316.765 238.588 1.00 79.89  ? 825  LEU A N     1 
ATOM   5400  C CA    . LEU A 1 825  ? 178.497 316.088 239.844 1.00 79.89  ? 825  LEU A CA    1 
ATOM   5401  C C     . LEU A 1 825  ? 179.986 315.989 240.141 1.00 79.89  ? 825  LEU A C     1 
ATOM   5402  O O     . LEU A 1 825  ? 180.359 315.387 241.155 1.00 79.89  ? 825  LEU A O     1 
ATOM   5403  C CB    . LEU A 1 825  ? 177.880 314.678 239.861 1.00 79.89  ? 825  LEU A CB    1 
ATOM   5404  C CG    . LEU A 1 825  ? 178.389 313.538 238.965 1.00 79.89  ? 825  LEU A CG    1 
ATOM   5405  C CD1   . LEU A 1 825  ? 177.502 312.314 239.138 1.00 79.89  ? 825  LEU A CD1   1 
ATOM   5406  C CD2   . LEU A 1 825  ? 178.459 313.911 237.490 1.00 79.89  ? 825  LEU A CD2   1 
ATOM   5407  N N     . ILE A 1 826  ? 180.846 316.555 239.290 1.00 72.58  ? 826  ILE A N     1 
ATOM   5408  C CA    . ILE A 1 826  ? 182.284 316.514 239.542 1.00 72.58  ? 826  ILE A CA    1 
ATOM   5409  C C     . ILE A 1 826  ? 182.627 317.295 240.804 1.00 72.58  ? 826  ILE A C     1 
ATOM   5410  O O     . ILE A 1 826  ? 183.441 316.854 241.626 1.00 72.58  ? 826  ILE A O     1 
ATOM   5411  C CB    . ILE A 1 826  ? 183.055 317.040 238.317 1.00 72.58  ? 826  ILE A CB    1 
ATOM   5412  C CG1   . ILE A 1 826  ? 182.984 316.026 237.174 1.00 72.58  ? 826  ILE A CG1   1 
ATOM   5413  C CG2   . ILE A 1 826  ? 184.504 317.336 238.676 1.00 72.58  ? 826  ILE A CG2   1 
ATOM   5414  C CD1   . ILE A 1 826  ? 183.423 316.575 235.837 1.00 72.58  ? 826  ILE A CD1   1 
ATOM   5415  N N     . ARG A 1 827  ? 182.012 318.468 240.979 1.00 75.34  ? 827  ARG A N     1 
ATOM   5416  C CA    . ARG A 1 827  ? 182.251 319.260 242.181 1.00 75.34  ? 827  ARG A CA    1 
ATOM   5417  C C     . ARG A 1 827  ? 181.810 318.508 243.430 1.00 75.34  ? 827  ARG A C     1 
ATOM   5418  O O     . ARG A 1 827  ? 182.513 318.511 244.448 1.00 75.34  ? 827  ARG A O     1 
ATOM   5419  C CB    . ARG A 1 827  ? 181.522 320.599 242.079 1.00 75.34  ? 827  ARG A CB    1 
ATOM   5420  C CG    . ARG A 1 827  ? 181.609 321.252 240.709 1.00 75.34  ? 827  ARG A CG    1 
ATOM   5421  C CD    . ARG A 1 827  ? 182.832 322.143 240.588 1.00 75.34  ? 827  ARG A CD    1 
ATOM   5422  N NE    . ARG A 1 827  ? 182.727 323.052 239.453 1.00 75.34  ? 827  ARG A NE    1 
ATOM   5423  C CZ    . ARG A 1 827  ? 183.764 323.574 238.812 1.00 75.34  ? 827  ARG A CZ    1 
ATOM   5424  N NH1   . ARG A 1 827  ? 185.007 323.305 239.174 1.00 75.34  ? 827  ARG A NH1   1 
ATOM   5425  N NH2   . ARG A 1 827  ? 183.547 324.386 237.782 1.00 75.34  ? 827  ARG A NH2   1 
ATOM   5426  N N     . TYR A 1 828  ? 180.647 317.855 243.369 1.00 80.14  ? 828  TYR A N     1 
ATOM   5427  C CA    . TYR A 1 828  ? 180.167 317.078 244.508 1.00 80.14  ? 828  TYR A CA    1 
ATOM   5428  C C     . TYR A 1 828  ? 181.107 315.921 244.822 1.00 80.14  ? 828  TYR A C     1 
ATOM   5429  O O     . TYR A 1 828  ? 181.395 315.645 245.992 1.00 80.14  ? 828  TYR A O     1 
ATOM   5430  C CB    . TYR A 1 828  ? 178.755 316.563 244.230 1.00 80.14  ? 828  TYR A CB    1 
ATOM   5431  C CG    . TYR A 1 828  ? 177.799 316.725 245.390 1.00 80.14  ? 828  TYR A CG    1 
ATOM   5432  C CD1   . TYR A 1 828  ? 178.225 316.536 246.698 1.00 80.14  ? 828  TYR A CD1   1 
ATOM   5433  C CD2   . TYR A 1 828  ? 176.470 317.066 245.176 1.00 80.14  ? 828  TYR A CD2   1 
ATOM   5434  C CE1   . TYR A 1 828  ? 177.353 316.684 247.760 1.00 80.14  ? 828  TYR A CE1   1 
ATOM   5435  C CE2   . TYR A 1 828  ? 175.592 317.216 246.232 1.00 80.14  ? 828  TYR A CE2   1 
ATOM   5436  C CZ    . TYR A 1 828  ? 176.038 317.024 247.522 1.00 80.14  ? 828  TYR A CZ    1 
ATOM   5437  O OH    . TYR A 1 828  ? 175.167 317.171 248.576 1.00 80.14  ? 828  TYR A OH    1 
ATOM   5438  N N     . ILE A 1 829  ? 181.593 315.231 243.787 1.00 73.07  ? 829  ILE A N     1 
ATOM   5439  C CA    . ILE A 1 829  ? 182.511 314.114 243.995 1.00 73.07  ? 829  ILE A CA    1 
ATOM   5440  C C     . ILE A 1 829  ? 183.803 314.601 244.639 1.00 73.07  ? 829  ILE A C     1 
ATOM   5441  O O     . ILE A 1 829  ? 184.316 313.987 245.585 1.00 73.07  ? 829  ILE A O     1 
ATOM   5442  C CB    . ILE A 1 829  ? 182.780 313.391 242.662 1.00 73.07  ? 829  ILE A CB    1 
ATOM   5443  C CG1   . ILE A 1 829  ? 181.546 312.599 242.221 1.00 73.07  ? 829  ILE A CG1   1 
ATOM   5444  C CG2   . ILE A 1 829  ? 183.990 312.477 242.782 1.00 73.07  ? 829  ILE A CG2   1 
ATOM   5445  C CD1   . ILE A 1 829  ? 181.369 311.280 242.933 1.00 73.07  ? 829  ILE A CD1   1 
ATOM   5446  N N     . SER A 1 830  ? 184.347 315.714 244.139 1.00 71.60  ? 830  SER A N     1 
ATOM   5447  C CA    . SER A 1 830  ? 185.576 316.261 244.707 1.00 71.60  ? 830  SER A CA    1 
ATOM   5448  C C     . SER A 1 830  ? 185.373 316.690 246.154 1.00 71.60  ? 830  SER A C     1 
ATOM   5449  O O     . SER A 1 830  ? 186.248 316.474 247.001 1.00 71.60  ? 830  SER A O     1 
ATOM   5450  C CB    . SER A 1 830  ? 186.066 317.436 243.861 1.00 71.60  ? 830  SER A CB    1 
ATOM   5451  O OG    . SER A 1 830  ? 186.667 316.985 242.660 1.00 71.60  ? 830  SER A OG    1 
ATOM   5452  N N     . GLY A 1 831  ? 184.229 317.306 246.456 1.00 78.91  ? 831  GLY A N     1 
ATOM   5453  C CA    . GLY A 1 831  ? 183.953 317.698 247.828 1.00 78.91  ? 831  GLY A CA    1 
ATOM   5454  C C     . GLY A 1 831  ? 183.809 316.509 248.759 1.00 78.91  ? 831  GLY A C     1 
ATOM   5455  O O     . GLY A 1 831  ? 184.267 316.546 249.904 1.00 78.91  ? 831  GLY A O     1 
ATOM   5456  N N     . ILE A 1 832  ? 183.163 315.441 248.284 1.00 77.61  ? 832  ILE A N     1 
ATOM   5457  C CA    . ILE A 1 832  ? 183.025 314.233 249.094 1.00 77.61  ? 832  ILE A CA    1 
ATOM   5458  C C     . ILE A 1 832  ? 184.391 313.611 249.354 1.00 77.61  ? 832  ILE A C     1 
ATOM   5459  O O     . ILE A 1 832  ? 184.709 313.213 250.481 1.00 77.61  ? 832  ILE A O     1 
ATOM   5460  C CB    . ILE A 1 832  ? 182.068 313.237 248.414 1.00 77.61  ? 832  ILE A CB    1 
ATOM   5461  C CG1   . ILE A 1 832  ? 180.625 313.738 248.504 1.00 77.61  ? 832  ILE A CG1   1 
ATOM   5462  C CG2   . ILE A 1 832  ? 182.191 311.856 249.042 1.00 77.61  ? 832  ILE A CG2   1 
ATOM   5463  C CD1   . ILE A 1 832  ? 179.716 313.179 247.432 1.00 77.61  ? 832  ILE A CD1   1 
ATOM   5464  N N     . LEU A 1 833  ? 185.225 313.528 248.316 1.00 72.54  ? 833  LEU A N     1 
ATOM   5465  C CA    . LEU A 1 833  ? 186.567 312.978 248.475 1.00 72.54  ? 833  LEU A CA    1 
ATOM   5466  C C     . LEU A 1 833  ? 187.499 313.904 249.244 1.00 72.54  ? 833  LEU A C     1 
ATOM   5467  O O     . LEU A 1 833  ? 188.605 313.479 249.597 1.00 72.54  ? 833  LEU A O     1 
ATOM   5468  C CB    . LEU A 1 833  ? 187.176 312.659 247.109 1.00 72.54  ? 833  LEU A CB    1 
ATOM   5469  C CG    . LEU A 1 833  ? 186.999 311.229 246.593 1.00 72.54  ? 833  LEU A CG    1 
ATOM   5470  C CD1   . LEU A 1 833  ? 185.545 310.952 246.258 1.00 72.54  ? 833  LEU A CD1   1 
ATOM   5471  C CD2   . LEU A 1 833  ? 187.886 310.975 245.385 1.00 72.54  ? 833  LEU A CD2   1 
ATOM   5472  N N     . ARG A 1 834  ? 187.086 315.147 249.503 1.00 79.46  ? 834  ARG A N     1 
ATOM   5473  C CA    . ARG A 1 834  ? 187.901 316.130 250.219 1.00 79.46  ? 834  ARG A CA    1 
ATOM   5474  C C     . ARG A 1 834  ? 189.233 316.381 249.517 1.00 79.46  ? 834  ARG A C     1 
ATOM   5475  O O     . ARG A 1 834  ? 190.253 316.627 250.167 1.00 79.46  ? 834  ARG A O     1 
ATOM   5476  C CB    . ARG A 1 834  ? 188.135 315.711 251.675 1.00 79.46  ? 834  ARG A CB    1 
ATOM   5477  C CG    . ARG A 1 834  ? 186.863 315.568 252.495 1.00 79.46  ? 834  ARG A CG    1 
ATOM   5478  C CD    . ARG A 1 834  ? 186.239 316.925 252.780 1.00 79.46  ? 834  ARG A CD    1 
ATOM   5479  N NE    . ARG A 1 834  ? 185.182 316.842 253.781 1.00 79.46  ? 834  ARG A NE    1 
ATOM   5480  C CZ    . ARG A 1 834  ? 184.648 317.888 254.395 1.00 79.46  ? 834  ARG A CZ    1 
ATOM   5481  N NH1   . ARG A 1 834  ? 185.049 319.122 254.134 1.00 79.46  ? 834  ARG A NH1   1 
ATOM   5482  N NH2   . ARG A 1 834  ? 183.687 317.693 255.294 1.00 79.46  ? 834  ARG A NH2   1 
ATOM   5483  N N     . LYS A 1 835  ? 189.235 316.319 248.188 1.00 73.45  ? 835  LYS A N     1 
ATOM   5484  C CA    . LYS A 1 835  ? 190.446 316.596 247.428 1.00 73.45  ? 835  LYS A CA    1 
ATOM   5485  C C     . LYS A 1 835  ? 190.798 318.075 247.528 1.00 73.45  ? 835  LYS A C     1 
ATOM   5486  O O     . LYS A 1 835  ? 189.935 318.943 247.365 1.00 73.45  ? 835  LYS A O     1 
ATOM   5487  C CB    . LYS A 1 835  ? 190.265 316.191 245.967 1.00 73.45  ? 835  LYS A CB    1 
ATOM   5488  C CG    . LYS A 1 835  ? 189.909 314.728 245.767 1.00 73.45  ? 835  LYS A CG    1 
ATOM   5489  C CD    . LYS A 1 835  ? 189.771 314.393 244.291 1.00 73.45  ? 835  LYS A CD    1 
ATOM   5490  C CE    . LYS A 1 835  ? 190.490 313.098 243.951 1.00 73.45  ? 835  LYS A CE    1 
ATOM   5491  N NZ    . LYS A 1 835  ? 191.966 313.282 243.885 1.00 73.45  ? 835  LYS A NZ    1 
ATOM   5492  N N     . LYS A 1 836  ? 192.068 318.360 247.796 1.00 80.21  ? 836  LYS A N     1 
ATOM   5493  C CA    . LYS A 1 836  ? 192.552 319.721 247.964 1.00 80.21  ? 836  LYS A CA    1 
ATOM   5494  C C     . LYS A 1 836  ? 193.544 320.057 246.859 1.00 80.21  ? 836  LYS A C     1 
ATOM   5495  O O     . LYS A 1 836  ? 194.328 319.202 246.434 1.00 80.21  ? 836  LYS A O     1 
ATOM   5496  C CB    . LYS A 1 836  ? 193.208 319.903 249.336 1.00 80.21  ? 836  LYS A CB    1 
ATOM   5497  C CG    . LYS A 1 836  ? 192.355 319.410 250.496 1.00 80.21  ? 836  LYS A CG    1 
ATOM   5498  C CD    . LYS A 1 836  ? 190.958 320.011 250.452 1.00 80.21  ? 836  LYS A CD    1 
ATOM   5499  C CE    . LYS A 1 836  ? 190.177 319.697 251.717 1.00 80.21  ? 836  LYS A CE    1 
ATOM   5500  N NZ    . LYS A 1 836  ? 190.975 319.953 252.946 1.00 80.21  ? 836  LYS A NZ    1 
ATOM   5501  N N     . VAL A 1 837  ? 193.497 321.306 246.392 1.00 83.45  ? 837  VAL A N     1 
ATOM   5502  C CA    . VAL A 1 837  ? 194.397 321.740 245.331 1.00 83.45  ? 837  VAL A CA    1 
ATOM   5503  C C     . VAL A 1 837  ? 195.829 321.714 245.839 1.00 83.45  ? 837  VAL A C     1 
ATOM   5504  O O     . VAL A 1 837  ? 196.128 322.204 246.936 1.00 83.45  ? 837  VAL A O     1 
ATOM   5505  C CB    . VAL A 1 837  ? 194.000 323.138 244.834 1.00 83.45  ? 837  VAL A CB    1 
ATOM   5506  C CG1   . VAL A 1 837  ? 195.032 323.671 243.850 1.00 83.45  ? 837  VAL A CG1   1 
ATOM   5507  C CG2   . VAL A 1 837  ? 192.619 323.102 244.197 1.00 83.45  ? 837  VAL A CG2   1 
ATOM   5508  N N     . GLU A 1 838  ? 196.722 321.129 245.046 1.00 80.04  ? 838  GLU A N     1 
ATOM   5509  C CA    . GLU A 1 838  ? 198.122 321.039 245.432 1.00 80.04  ? 838  GLU A CA    1 
ATOM   5510  C C     . GLU A 1 838  ? 198.763 322.423 245.466 1.00 80.04  ? 838  GLU A C     1 
ATOM   5511  O O     . GLU A 1 838  ? 198.385 323.327 244.715 1.00 80.04  ? 838  GLU A O     1 
ATOM   5512  C CB    . GLU A 1 838  ? 198.883 320.131 244.466 1.00 80.04  ? 838  GLU A CB    1 
ATOM   5513  C CG    . GLU A 1 838  ? 200.045 319.390 245.102 1.00 80.04  ? 838  GLU A CG    1 
ATOM   5514  C CD    . GLU A 1 838  ? 199.597 318.205 245.935 1.00 80.04  ? 838  GLU A CD    1 
ATOM   5515  O OE1   . GLU A 1 838  ? 198.933 317.304 245.382 1.00 80.04  ? 838  GLU A OE1   1 
ATOM   5516  O OE2   . GLU A 1 838  ? 199.909 318.175 247.144 1.00 80.04  ? 838  GLU A OE2   1 
ATOM   5517  N N     . ALA A 1 839  ? 199.743 322.577 246.360 1.00 79.74  ? 839  ALA A N     1 
ATOM   5518  C CA    . ALA A 1 839  ? 200.470 323.834 246.547 1.00 79.74  ? 839  ALA A CA    1 
ATOM   5519  C C     . ALA A 1 839  ? 199.536 324.992 246.888 1.00 79.74  ? 839  ALA A C     1 
ATOM   5520  O O     . ALA A 1 839  ? 199.735 326.120 246.430 1.00 79.74  ? 839  ALA A O     1 
ATOM   5521  C CB    . ALA A 1 839  ? 201.319 324.176 245.318 1.00 79.74  ? 839  ALA A CB    1 
ATOM   5522  N N     . LEU A 1 840  ? 198.503 324.720 247.691 1.00 80.72  ? 840  LEU A N     1 
ATOM   5523  C CA    . LEU A 1 840  ? 197.613 325.789 248.136 1.00 80.72  ? 840  LEU A CA    1 
ATOM   5524  C C     . LEU A 1 840  ? 198.347 326.777 249.034 1.00 80.72  ? 840  LEU A C     1 
ATOM   5525  O O     . LEU A 1 840  ? 198.107 327.988 248.964 1.00 80.72  ? 840  LEU A O     1 
ATOM   5526  C CB    . LEU A 1 840  ? 196.402 325.200 248.860 1.00 80.72  ? 840  LEU A CB    1 
ATOM   5527  C CG    . LEU A 1 840  ? 195.113 325.094 248.042 1.00 80.72  ? 840  LEU A CG    1 
ATOM   5528  C CD1   . LEU A 1 840  ? 194.108 324.188 248.737 1.00 80.72  ? 840  LEU A CD1   1 
ATOM   5529  C CD2   . LEU A 1 840  ? 194.518 326.472 247.794 1.00 80.72  ? 840  LEU A CD2   1 
ATOM   5530  N N     . ASP A 1 841  ? 199.238 326.277 249.894 1.00 83.77  ? 841  ASP A N     1 
ATOM   5531  C CA    . ASP A 1 841  ? 200.022 327.162 250.749 1.00 83.77  ? 841  ASP A CA    1 
ATOM   5532  C C     . ASP A 1 841  ? 200.942 328.053 249.923 1.00 83.77  ? 841  ASP A C     1 
ATOM   5533  O O     . ASP A 1 841  ? 201.163 329.220 250.269 1.00 83.77  ? 841  ASP A O     1 
ATOM   5534  C CB    . ASP A 1 841  ? 200.826 326.341 251.758 1.00 83.77  ? 841  ASP A CB    1 
ATOM   5535  C CG    . ASP A 1 841  ? 201.602 325.213 251.106 1.00 83.77  ? 841  ASP A CG    1 
ATOM   5536  O OD1   . ASP A 1 841  ? 201.478 325.035 249.875 1.00 83.77  ? 841  ASP A OD1   1 
ATOM   5537  O OD2   . ASP A 1 841  ? 202.335 324.502 251.825 1.00 83.77  ? 841  ASP A OD2   1 
ATOM   5538  N N     . GLU A 1 842  ? 201.495 327.516 248.833 1.00 76.60  ? 842  GLU A N     1 
ATOM   5539  C CA    . GLU A 1 842  ? 202.315 328.326 247.939 1.00 76.60  ? 842  GLU A CA    1 
ATOM   5540  C C     . GLU A 1 842  ? 201.502 329.466 247.337 1.00 76.60  ? 842  GLU A C     1 
ATOM   5541  O O     . GLU A 1 842  ? 201.962 330.612 247.278 1.00 76.60  ? 842  GLU A O     1 
ATOM   5542  C CB    . GLU A 1 842  ? 202.911 327.447 246.838 1.00 76.60  ? 842  GLU A CB    1 
ATOM   5543  C CG    . GLU A 1 842  ? 203.861 328.174 245.900 1.00 76.60  ? 842  GLU A CG    1 
ATOM   5544  C CD    . GLU A 1 842  ? 205.025 328.815 246.628 1.00 76.60  ? 842  GLU A CD    1 
ATOM   5545  O OE1   . GLU A 1 842  ? 206.029 328.114 246.872 1.00 76.60  ? 842  GLU A OE1   1 
ATOM   5546  O OE2   . GLU A 1 842  ? 204.940 330.018 246.950 1.00 76.60  ? 842  GLU A OE2   1 
ATOM   5547  N N     . ALA A 1 843  ? 200.279 329.167 246.892 1.00 78.08  ? 843  ALA A N     1 
ATOM   5548  C CA    . ALA A 1 843  ? 199.411 330.211 246.359 1.00 78.08  ? 843  ALA A CA    1 
ATOM   5549  C C     . ALA A 1 843  ? 199.075 331.245 247.425 1.00 78.08  ? 843  ALA A C     1 
ATOM   5550  O O     . ALA A 1 843  ? 199.071 332.452 247.153 1.00 78.08  ? 843  ALA A O     1 
ATOM   5551  C CB    . ALA A 1 843  ? 198.136 329.589 245.792 1.00 78.08  ? 843  ALA A CB    1 
ATOM   5552  N N     . CYS A 1 844  ? 198.798 330.789 248.650 1.00 83.51  ? 844  CYS A N     1 
ATOM   5553  C CA    . CYS A 1 844  ? 198.462 331.713 249.727 1.00 83.51  ? 844  CYS A CA    1 
ATOM   5554  C C     . CYS A 1 844  ? 199.623 332.647 250.044 1.00 83.51  ? 844  CYS A C     1 
ATOM   5555  O O     . CYS A 1 844  ? 199.429 333.859 250.192 1.00 83.51  ? 844  CYS A O     1 
ATOM   5556  C CB    . CYS A 1 844  ? 198.045 330.937 250.976 1.00 83.51  ? 844  CYS A CB    1 
ATOM   5557  S SG    . CYS A 1 844  ? 196.262 330.714 251.153 1.00 83.51  ? 844  CYS A SG    1 
ATOM   5558  N N     . THR A 1 845  ? 200.841 332.107 250.143 1.00 85.14  ? 845  THR A N     1 
ATOM   5559  C CA    . THR A 1 845  ? 201.979 332.961 250.471 1.00 85.14  ? 845  THR A CA    1 
ATOM   5560  C C     . THR A 1 845  ? 202.333 333.879 249.306 1.00 85.14  ? 845  THR A C     1 
ATOM   5561  O O     . THR A 1 845  ? 202.750 335.023 249.519 1.00 85.14  ? 845  THR A O     1 
ATOM   5562  C CB    . THR A 1 845  ? 203.186 332.121 250.904 1.00 85.14  ? 845  THR A CB    1 
ATOM   5563  O OG1   . THR A 1 845  ? 204.253 332.990 251.306 1.00 85.14  ? 845  THR A OG1   1 
ATOM   5564  C CG2   . THR A 1 845  ? 203.675 331.223 249.783 1.00 85.14  ? 845  THR A CG2   1 
ATOM   5565  N N     . ASP A 1 846  ? 202.145 333.413 248.066 1.00 87.68  ? 846  ASP A N     1 
ATOM   5566  C CA    . ASP A 1 846  ? 202.355 334.288 246.917 1.00 87.68  ? 846  ASP A CA    1 
ATOM   5567  C C     . ASP A 1 846  ? 201.369 335.450 246.927 1.00 87.68  ? 846  ASP A C     1 
ATOM   5568  O O     . ASP A 1 846  ? 201.738 336.590 246.621 1.00 87.68  ? 846  ASP A O     1 
ATOM   5569  C CB    . ASP A 1 846  ? 202.233 333.490 245.619 1.00 87.68  ? 846  ASP A CB    1 
ATOM   5570  C CG    . ASP A 1 846  ? 203.497 332.723 245.286 1.00 87.68  ? 846  ASP A CG    1 
ATOM   5571  O OD1   . ASP A 1 846  ? 204.560 333.050 245.855 1.00 87.68  ? 846  ASP A OD1   1 
ATOM   5572  O OD2   . ASP A 1 846  ? 203.429 331.793 244.455 1.00 87.68  ? 846  ASP A OD2   1 
ATOM   5573  N N     . LEU A 1 847  ? 200.108 335.178 247.273 1.00 86.65  ? 847  LEU A N     1 
ATOM   5574  C CA    . LEU A 1 847  ? 199.120 336.248 247.360 1.00 86.65  ? 847  LEU A CA    1 
ATOM   5575  C C     . LEU A 1 847  ? 199.437 337.207 248.503 1.00 86.65  ? 847  LEU A C     1 
ATOM   5576  O O     . LEU A 1 847  ? 199.297 338.427 248.356 1.00 86.65  ? 847  LEU A O     1 
ATOM   5577  C CB    . LEU A 1 847  ? 197.720 335.656 247.527 1.00 86.65  ? 847  LEU A CB    1 
ATOM   5578  C CG    . LEU A 1 847  ? 196.984 335.285 246.237 1.00 86.65  ? 847  LEU A CG    1 
ATOM   5579  C CD1   . LEU A 1 847  ? 195.847 334.316 246.525 1.00 86.65  ? 847  LEU A CD1   1 
ATOM   5580  C CD2   . LEU A 1 847  ? 196.467 336.531 245.535 1.00 86.65  ? 847  LEU A CD2   1 
ATOM   5581  N N     . LEU A 1 848  ? 199.866 336.675 249.650 1.00 85.67  ? 848  LEU A N     1 
ATOM   5582  C CA    . LEU A 1 848  ? 200.127 337.508 250.818 1.00 85.67  ? 848  LEU A CA    1 
ATOM   5583  C C     . LEU A 1 848  ? 201.439 338.278 250.726 1.00 85.67  ? 848  LEU A C     1 
ATOM   5584  O O     . LEU A 1 848  ? 201.629 339.237 251.482 1.00 85.67  ? 848  LEU A O     1 
ATOM   5585  C CB    . LEU A 1 848  ? 200.129 336.654 252.089 1.00 85.67  ? 848  LEU A CB    1 
ATOM   5586  C CG    . LEU A 1 848  ? 198.805 336.004 252.497 1.00 85.67  ? 848  LEU A CG    1 
ATOM   5587  C CD1   . LEU A 1 848  ? 199.055 334.766 253.345 1.00 85.67  ? 848  LEU A CD1   1 
ATOM   5588  C CD2   . LEU A 1 848  ? 197.926 336.994 253.243 1.00 85.67  ? 848  LEU A CD2   1 
ATOM   5589  N N     . SER A 1 849  ? 202.347 337.882 249.830 1.00 83.07  ? 849  SER A N     1 
ATOM   5590  C CA    . SER A 1 849  ? 203.624 338.577 249.711 1.00 83.07  ? 849  SER A CA    1 
ATOM   5591  C C     . SER A 1 849  ? 203.475 340.014 249.226 1.00 83.07  ? 849  SER A C     1 
ATOM   5592  O O     . SER A 1 849  ? 204.417 340.800 249.370 1.00 83.07  ? 849  SER A O     1 
ATOM   5593  C CB    . SER A 1 849  ? 204.550 337.811 248.765 1.00 83.07  ? 849  SER A CB    1 
ATOM   5594  O OG    . SER A 1 849  ? 204.165 337.996 247.415 1.00 83.07  ? 849  SER A OG    1 
ATOM   5595  N N     . HIS A 1 850  ? 202.323 340.377 248.661 1.00 84.13  ? 850  HIS A N     1 
ATOM   5596  C CA    . HIS A 1 850  ? 202.098 341.715 248.128 1.00 84.13  ? 850  HIS A CA    1 
ATOM   5597  C C     . HIS A 1 850  ? 201.201 342.558 249.028 1.00 84.13  ? 850  HIS A C     1 
ATOM   5598  O O     . HIS A 1 850  ? 200.509 343.459 248.541 1.00 84.13  ? 850  HIS A O     1 
ATOM   5599  C CB    . HIS A 1 850  ? 201.508 341.631 246.721 1.00 84.13  ? 850  HIS A CB    1 
ATOM   5600  C CG    . HIS A 1 850  ? 202.495 341.216 245.675 1.00 84.13  ? 850  HIS A CG    1 
ATOM   5601  N ND1   . HIS A 1 850  ? 203.198 342.124 244.912 1.00 84.13  ? 850  HIS A ND1   1 
ATOM   5602  C CD2   . HIS A 1 850  ? 202.893 339.989 245.261 1.00 84.13  ? 850  HIS A CD2   1 
ATOM   5603  C CE1   . HIS A 1 850  ? 203.988 341.475 244.076 1.00 84.13  ? 850  HIS A CE1   1 
ATOM   5604  N NE2   . HIS A 1 850  ? 203.822 340.178 244.267 1.00 84.13  ? 850  HIS A NE2   1 
ATOM   5605  N N     . GLN A 1 851  ? 201.200 342.279 250.333 1.00 82.12  ? 851  GLN A N     1 
ATOM   5606  C CA    . GLN A 1 851  ? 200.411 343.024 251.315 1.00 82.12  ? 851  GLN A CA    1 
ATOM   5607  C C     . GLN A 1 851  ? 198.922 342.999 250.958 1.00 82.12  ? 851  GLN A C     1 
ATOM   5608  O O     . GLN A 1 851  ? 198.293 344.028 250.704 1.00 82.12  ? 851  GLN A O     1 
ATOM   5609  C CB    . GLN A 1 851  ? 200.923 344.463 251.454 1.00 82.12  ? 851  GLN A CB    1 
ATOM   5610  C CG    . GLN A 1 851  ? 202.389 344.576 251.849 1.00 82.12  ? 851  GLN A CG    1 
ATOM   5611  C CD    . GLN A 1 851  ? 203.320 344.614 250.652 1.00 82.12  ? 851  GLN A CD    1 
ATOM   5612  O OE1   . GLN A 1 851  ? 203.862 343.588 250.240 1.00 82.12  ? 851  GLN A OE1   1 
ATOM   5613  N NE2   . GLN A 1 851  ? 203.508 345.800 250.085 1.00 82.12  ? 851  GLN A NE2   1 
ATOM   5614  N N     . LYS A 1 852  ? 198.366 341.789 250.943 1.00 85.53  ? 852  LYS A N     1 
ATOM   5615  C CA    . LYS A 1 852  ? 196.962 341.574 250.628 1.00 85.53  ? 852  LYS A CA    1 
ATOM   5616  C C     . LYS A 1 852  ? 196.308 340.759 251.733 1.00 85.53  ? 852  LYS A C     1 
ATOM   5617  O O     . LYS A 1 852  ? 196.973 340.003 252.447 1.00 85.53  ? 852  LYS A O     1 
ATOM   5618  C CB    . LYS A 1 852  ? 196.788 340.858 249.279 1.00 85.53  ? 852  LYS A CB    1 
ATOM   5619  C CG    . LYS A 1 852  ? 197.625 341.436 248.149 1.00 85.53  ? 852  LYS A CG    1 
ATOM   5620  C CD    . LYS A 1 852  ? 197.186 342.850 247.803 1.00 85.53  ? 852  LYS A CD    1 
ATOM   5621  C CE    . LYS A 1 852  ? 196.827 342.972 246.331 1.00 85.53  ? 852  LYS A CE    1 
ATOM   5622  N NZ    . LYS A 1 852  ? 196.707 344.394 245.905 1.00 85.53  ? 852  LYS A NZ    1 
ATOM   5623  N N     . HIS A 1 853  ? 194.995 340.923 251.870 1.00 91.82  ? 853  HIS A N     1 
ATOM   5624  C CA    . HIS A 1 853  ? 194.208 340.217 252.870 1.00 91.82  ? 853  HIS A CA    1 
ATOM   5625  C C     . HIS A 1 853  ? 193.204 339.300 252.186 1.00 91.82  ? 853  HIS A C     1 
ATOM   5626  O O     . HIS A 1 853  ? 192.576 339.680 251.192 1.00 91.82  ? 853  HIS A O     1 
ATOM   5627  C CB    . HIS A 1 853  ? 193.478 341.199 253.790 1.00 91.82  ? 853  HIS A CB    1 
ATOM   5628  C CG    . HIS A 1 853  ? 194.325 341.724 254.907 1.00 91.82  ? 853  HIS A CG    1 
ATOM   5629  N ND1   . HIS A 1 853  ? 194.441 343.069 255.185 1.00 91.82  ? 853  HIS A ND1   1 
ATOM   5630  C CD2   . HIS A 1 853  ? 195.100 341.084 255.814 1.00 91.82  ? 853  HIS A CD2   1 
ATOM   5631  C CE1   . HIS A 1 853  ? 195.249 343.234 256.217 1.00 91.82  ? 853  HIS A CE1   1 
ATOM   5632  N NE2   . HIS A 1 853  ? 195.663 342.046 256.617 1.00 91.82  ? 853  HIS A NE2   1 
ATOM   5633  N N     . LEU A 1 854  ? 193.056 338.092 252.721 1.00 83.49  ? 854  LEU A N     1 
ATOM   5634  C CA    . LEU A 1 854  ? 192.151 337.104 252.143 1.00 83.49  ? 854  LEU A CA    1 
ATOM   5635  C C     . LEU A 1 854  ? 190.994 336.778 253.085 1.00 83.49  ? 854  LEU A C     1 
ATOM   5636  O O     . LEU A 1 854  ? 191.202 336.490 254.264 1.00 83.49  ? 854  LEU A O     1 
ATOM   5637  C CB    . LEU A 1 854  ? 192.914 335.823 251.791 1.00 83.49  ? 854  LEU A CB    1 
ATOM   5638  C CG    . LEU A 1 854  ? 193.486 335.717 250.374 1.00 83.49  ? 854  LEU A CG    1 
ATOM   5639  C CD1   . LEU A 1 854  ? 194.614 336.715 250.159 1.00 83.49  ? 854  LEU A CD1   1 
ATOM   5640  C CD2   . LEU A 1 854  ? 193.960 334.299 250.093 1.00 83.49  ? 854  LEU A CD2   1 
HETATM 5641  N N     . TPO A 1 855  ? 189.777 336.826 252.553 1.00 81.22  ? 855  TPO A N     1 
HETATM 5642  C CA    . TPO A 1 855  ? 188.581 336.495 253.322 1.00 81.22  ? 855  TPO A CA    1 
HETATM 5643  C CB    . TPO A 1 855  ? 187.794 337.753 253.650 1.00 81.22  ? 855  TPO A CB    1 
HETATM 5644  C C     . TPO A 1 855  ? 187.712 335.503 252.555 1.00 81.22  ? 855  TPO A C     1 
HETATM 5645  O O     . TPO A 1 855  ? 187.276 335.781 251.439 1.00 81.22  ? 855  TPO A O     1 
ATOM   5646  N N     . VAL A 1 856  ? 187.459 334.348 253.162 1.00 77.11  ? 856  VAL A N     1 
ATOM   5647  C CA    . VAL A 1 856  ? 186.754 333.265 252.486 1.00 77.11  ? 856  VAL A CA    1 
ATOM   5648  C C     . VAL A 1 856  ? 185.281 333.201 252.883 1.00 77.11  ? 856  VAL A C     1 
ATOM   5649  O O     . VAL A 1 856  ? 184.928 333.410 254.044 1.00 77.11  ? 856  VAL A O     1 
ATOM   5650  C CB    . VAL A 1 856  ? 187.442 331.917 252.763 1.00 77.11  ? 856  VAL A CB    1 
ATOM   5651  C CG1   . VAL A 1 856  ? 188.689 331.774 251.907 1.00 77.11  ? 856  VAL A CG1   1 
ATOM   5652  C CG2   . VAL A 1 856  ? 187.798 331.800 254.236 1.00 77.11  ? 856  VAL A CG2   1 
ATOM   5653  N N     . GLY A 1 857  ? 184.426 332.910 251.904 1.00 87.04  ? 857  GLY A N     1 
ATOM   5654  C CA    . GLY A 1 857  ? 183.009 332.738 252.139 1.00 87.04  ? 857  GLY A CA    1 
ATOM   5655  C C     . GLY A 1 857  ? 182.249 334.052 252.194 1.00 87.04  ? 857  GLY A C     1 
ATOM   5656  O O     . GLY A 1 857  ? 182.813 335.147 252.136 1.00 87.04  ? 857  GLY A O     1 
ATOM   5657  N N     . LEU A 1 858  ? 180.927 333.927 252.302 1.00 94.71  ? 858  LEU A N     1 
ATOM   5658  C CA    . LEU A 1 858  ? 180.080 335.097 252.465 1.00 94.71  ? 858  LEU A CA    1 
ATOM   5659  C C     . LEU A 1 858  ? 180.419 335.789 253.784 1.00 94.71  ? 858  LEU A C     1 
ATOM   5660  O O     . LEU A 1 858  ? 180.851 335.135 254.735 1.00 94.71  ? 858  LEU A O     1 
ATOM   5661  C CB    . LEU A 1 858  ? 178.605 334.702 252.439 1.00 94.71  ? 858  LEU A CB    1 
ATOM   5662  N N     . PRO A 1 859  ? 180.326 337.116 253.836 1.00 105.11 ? 859  PRO A N     1 
ATOM   5663  C CA    . PRO A 1 859  ? 180.633 337.845 255.077 1.00 105.11 ? 859  PRO A CA    1 
ATOM   5664  C C     . PRO A 1 859  ? 179.426 337.982 255.991 1.00 105.11 ? 859  PRO A C     1 
ATOM   5665  O O     . PRO A 1 859  ? 178.494 338.741 255.685 1.00 105.11 ? 859  PRO A O     1 
ATOM   5666  C CB    . PRO A 1 859  ? 181.097 339.215 254.564 1.00 105.11 ? 859  PRO A CB    1 
ATOM   5667  C CG    . PRO A 1 859  ? 180.379 339.394 253.259 1.00 105.11 ? 859  PRO A CG    1 
ATOM   5668  C CD    . PRO A 1 859  ? 180.047 338.024 252.709 1.00 105.11 ? 859  PRO A CD    1 
ATOM   5669  N N     . PRO A 1 860  ? 179.394 337.272 257.116 1.00 116.55 ? 860  PRO A N     1 
ATOM   5670  C CA    . PRO A 1 860  ? 178.693 337.777 258.296 1.00 116.55 ? 860  PRO A CA    1 
ATOM   5671  C C     . PRO A 1 860  ? 179.688 338.448 259.237 1.00 116.55 ? 860  PRO A C     1 
ATOM   5672  O O     . PRO A 1 860  ? 180.901 338.428 259.020 1.00 116.55 ? 860  PRO A O     1 
ATOM   5673  C CB    . PRO A 1 860  ? 178.093 336.512 258.934 1.00 116.55 ? 860  PRO A CB    1 
ATOM   5674  C CG    . PRO A 1 860  ? 178.412 335.384 257.991 1.00 116.55 ? 860  PRO A CG    1 
ATOM   5675  C CD    . PRO A 1 860  ? 179.616 335.827 257.235 1.00 116.55 ? 860  PRO A CD    1 
ATOM   5676  N N     . GLU A 1 861  ? 179.148 339.051 260.293 1.00 127.59 ? 861  GLU A N     1 
ATOM   5677  C CA    . GLU A 1 861  ? 180.009 339.681 261.292 1.00 127.59 ? 861  GLU A CA    1 
ATOM   5678  C C     . GLU A 1 861  ? 180.893 338.687 262.042 1.00 127.59 ? 861  GLU A C     1 
ATOM   5679  O O     . GLU A 1 861  ? 182.118 338.896 262.078 1.00 127.59 ? 861  GLU A O     1 
ATOM   5680  C CB    . GLU A 1 861  ? 179.154 340.509 262.258 1.00 127.59 ? 861  GLU A CB    1 
ATOM   5681  C CG    . GLU A 1 861  ? 179.626 341.943 262.432 1.00 127.59 ? 861  GLU A CG    1 
ATOM   5682  C CD    . GLU A 1 861  ? 180.979 342.034 263.111 1.00 127.59 ? 861  GLU A CD    1 
ATOM   5683  O OE1   . GLU A 1 861  ? 181.274 341.178 263.971 1.00 127.59 ? 861  GLU A OE1   1 
ATOM   5684  O OE2   . GLU A 1 861  ? 181.749 342.962 262.784 1.00 127.59 ? 861  GLU A OE2   1 
ATOM   5685  N N     . PRO A 1 862  ? 180.368 337.602 262.660 1.00 124.42 ? 862  PRO A N     1 
ATOM   5686  C CA    . PRO A 1 862  ? 181.230 336.770 263.516 1.00 124.42 ? 862  PRO A CA    1 
ATOM   5687  C C     . PRO A 1 862  ? 182.281 335.953 262.774 1.00 124.42 ? 862  PRO A C     1 
ATOM   5688  O O     . PRO A 1 862  ? 183.466 336.008 263.117 1.00 124.42 ? 862  PRO A O     1 
ATOM   5689  C CB    . PRO A 1 862  ? 180.228 335.854 264.232 1.00 124.42 ? 862  PRO A CB    1 
ATOM   5690  C CG    . PRO A 1 862  ? 179.073 335.768 263.314 1.00 124.42 ? 862  PRO A CG    1 
ATOM   5691  C CD    . PRO A 1 862  ? 178.980 337.100 262.633 1.00 124.42 ? 862  PRO A CD    1 
ATOM   5692  N N     . ARG A 1 863  ? 181.866 335.195 261.762 1.00 117.84 ? 863  ARG A N     1 
ATOM   5693  C CA    . ARG A 1 863  ? 182.731 334.201 261.139 1.00 117.84 ? 863  ARG A CA    1 
ATOM   5694  C C     . ARG A 1 863  ? 183.632 334.858 260.092 1.00 117.84 ? 863  ARG A C     1 
ATOM   5695  O O     . ARG A 1 863  ? 183.806 336.079 260.064 1.00 117.84 ? 863  ARG A O     1 
ATOM   5696  C CB    . ARG A 1 863  ? 181.894 333.062 260.560 1.00 117.84 ? 863  ARG A CB    1 
ATOM   5697  C CG    . ARG A 1 863  ? 181.079 333.430 259.337 1.00 117.84 ? 863  ARG A CG    1 
ATOM   5698  C CD    . ARG A 1 863  ? 180.221 332.264 258.868 1.00 117.84 ? 863  ARG A CD    1 
ATOM   5699  N NE    . ARG A 1 863  ? 179.831 332.402 257.470 1.00 117.84 ? 863  ARG A NE    1 
ATOM   5700  C CZ    . ARG A 1 863  ? 178.842 331.728 256.898 1.00 117.84 ? 863  ARG A CZ    1 
ATOM   5701  N NH1   . ARG A 1 863  ? 178.116 330.855 257.577 1.00 117.84 ? 863  ARG A NH1   1 
ATOM   5702  N NH2   . ARG A 1 863  ? 178.574 331.937 255.612 1.00 117.84 ? 863  ARG A NH2   1 
ATOM   5703  N N     . GLU A 1 864  ? 184.242 334.023 259.244 1.00 98.74  ? 864  GLU A N     1 
ATOM   5704  C CA    . GLU A 1 864  ? 185.210 334.423 258.214 1.00 98.74  ? 864  GLU A CA    1 
ATOM   5705  C C     . GLU A 1 864  ? 186.296 335.342 258.784 1.00 98.74  ? 864  GLU A C     1 
ATOM   5706  O O     . GLU A 1 864  ? 186.500 336.475 258.342 1.00 98.74  ? 864  GLU A O     1 
ATOM   5707  C CB    . GLU A 1 864  ? 184.518 335.036 256.982 1.00 98.74  ? 864  GLU A CB    1 
ATOM   5708  C CG    . GLU A 1 864  ? 183.864 336.409 257.125 1.00 98.74  ? 864  GLU A CG    1 
ATOM   5709  C CD    . GLU A 1 864  ? 183.918 337.212 255.842 1.00 98.74  ? 864  GLU A CD    1 
ATOM   5710  O OE1   . GLU A 1 864  ? 184.064 336.603 254.761 1.00 98.74  ? 864  GLU A OE1   1 
ATOM   5711  O OE2   . GLU A 1 864  ? 183.834 338.455 255.917 1.00 98.74  ? 864  GLU A OE2   1 
ATOM   5712  N N     . LYS A 1 865  ? 187.018 334.821 259.774 1.00 102.16 ? 865  LYS A N     1 
ATOM   5713  C CA    . LYS A 1 865  ? 188.161 335.538 260.323 1.00 102.16 ? 865  LYS A CA    1 
ATOM   5714  C C     . LYS A 1 865  ? 189.195 335.790 259.232 1.00 102.16 ? 865  LYS A C     1 
ATOM   5715  O O     . LYS A 1 865  ? 189.506 334.899 258.435 1.00 102.16 ? 865  LYS A O     1 
ATOM   5716  C CB    . LYS A 1 865  ? 188.781 334.743 261.472 1.00 102.16 ? 865  LYS A CB    1 
ATOM   5717  N N     . THR A 1 866  ? 189.722 337.010 259.197 1.00 98.11  ? 866  THR A N     1 
ATOM   5718  C CA    . THR A 1 866  ? 190.649 337.397 258.144 1.00 98.11  ? 866  THR A CA    1 
ATOM   5719  C C     . THR A 1 866  ? 191.981 336.668 258.293 1.00 98.11  ? 866  THR A C     1 
ATOM   5720  O O     . THR A 1 866  ? 192.331 336.172 259.367 1.00 98.11  ? 866  THR A O     1 
ATOM   5721  C CB    . THR A 1 866  ? 190.879 338.909 258.160 1.00 98.11  ? 866  THR A CB    1 
ATOM   5722  O OG1   . THR A 1 866  ? 191.671 339.287 257.027 1.00 98.11  ? 866  THR A OG1   1 
ATOM   5723  C CG2   . THR A 1 866  ? 191.594 339.329 259.437 1.00 98.11  ? 866  THR A CG2   1 
ATOM   5724  N N     . ILE A 1 867  ? 192.722 336.602 257.190 1.00 93.51  ? 867  ILE A N     1 
ATOM   5725  C CA    . ILE A 1 867  ? 194.032 335.962 257.145 1.00 93.51  ? 867  ILE A CA    1 
ATOM   5726  C C     . ILE A 1 867  ? 195.071 337.047 256.902 1.00 93.51  ? 867  ILE A C     1 
ATOM   5727  O O     . ILE A 1 867  ? 194.994 337.782 255.909 1.00 93.51  ? 867  ILE A O     1 
ATOM   5728  C CB    . ILE A 1 867  ? 194.099 334.878 256.058 1.00 93.51  ? 867  ILE A CB    1 
ATOM   5729  C CG1   . ILE A 1 867  ? 193.325 333.630 256.494 1.00 93.51  ? 867  ILE A CG1   1 
ATOM   5730  C CG2   . ILE A 1 867  ? 195.545 334.527 255.740 1.00 93.51  ? 867  ILE A CG2   1 
ATOM   5731  C CD1   . ILE A 1 867  ? 191.869 333.628 256.074 1.00 93.51  ? 867  ILE A CD1   1 
ATOM   5732  N N     . SER A 1 868  ? 196.044 337.150 257.810 1.00 97.60  ? 868  SER A N     1 
ATOM   5733  C CA    . SER A 1 868  ? 197.087 338.159 257.719 1.00 97.60  ? 868  SER A CA    1 
ATOM   5734  C C     . SER A 1 868  ? 198.496 337.590 257.648 1.00 97.60  ? 868  SER A C     1 
ATOM   5735  O O     . SER A 1 868  ? 199.403 338.301 257.201 1.00 97.60  ? 868  SER A O     1 
ATOM   5736  C CB    . SER A 1 868  ? 197.009 339.123 258.914 1.00 97.60  ? 868  SER A CB    1 
ATOM   5737  O OG    . SER A 1 868  ? 196.171 340.228 258.624 1.00 97.60  ? 868  SER A OG    1 
ATOM   5738  N N     . ALA A 1 869  ? 198.707 336.351 258.067 1.00 103.23 ? 869  ALA A N     1 
ATOM   5739  C CA    . ALA A 1 869  ? 200.011 335.712 258.069 1.00 103.23 ? 869  ALA A CA    1 
ATOM   5740  C C     . ALA A 1 869  ? 199.907 334.345 257.413 1.00 103.23 ? 869  ALA A C     1 
ATOM   5741  O O     . ALA A 1 869  ? 198.840 333.722 257.426 1.00 103.23 ? 869  ALA A O     1 
ATOM   5742  C CB    . ALA A 1 869  ? 200.553 335.567 259.499 1.00 103.23 ? 869  ALA A CB    1 
ATOM   5743  N N     . PRO A 1 870  ? 200.996 333.856 256.817 1.00 97.44  ? 870  PRO A N     1 
ATOM   5744  C CA    . PRO A 1 870  ? 200.966 332.516 256.220 1.00 97.44  ? 870  PRO A CA    1 
ATOM   5745  C C     . PRO A 1 870  ? 200.686 331.446 257.263 1.00 97.44  ? 870  PRO A C     1 
ATOM   5746  O O     . PRO A 1 870  ? 201.108 331.542 258.418 1.00 97.44  ? 870  PRO A O     1 
ATOM   5747  C CB    . PRO A 1 870  ? 202.368 332.360 255.619 1.00 97.44  ? 870  PRO A CB    1 
ATOM   5748  C CG    . PRO A 1 870  ? 202.880 333.752 255.460 1.00 97.44  ? 870  PRO A CG    1 
ATOM   5749  C CD    . PRO A 1 870  ? 202.274 334.547 256.573 1.00 97.44  ? 870  PRO A CD    1 
ATOM   5750  N N     . LEU A 1 871  ? 199.965 330.417 256.841 1.00 97.23  ? 871  LEU A N     1 
ATOM   5751  C CA    . LEU A 1 871  ? 199.561 329.310 257.690 1.00 97.23  ? 871  LEU A CA    1 
ATOM   5752  C C     . LEU A 1 871  ? 199.945 327.998 257.027 1.00 97.23  ? 871  LEU A C     1 
ATOM   5753  O O     . LEU A 1 871  ? 200.075 327.928 255.800 1.00 97.23  ? 871  LEU A O     1 
ATOM   5754  C CB    . LEU A 1 871  ? 198.047 329.334 257.956 1.00 97.23  ? 871  LEU A CB    1 
ATOM   5755  C CG    . LEU A 1 871  ? 197.410 330.687 258.275 1.00 97.23  ? 871  LEU A CG    1 
ATOM   5756  C CD1   . LEU A 1 871  ? 196.696 331.244 257.053 1.00 97.23  ? 871  LEU A CD1   1 
ATOM   5757  C CD2   . LEU A 1 871  ? 196.453 330.567 259.452 1.00 97.23  ? 871  LEU A CD2   1 
ATOM   5758  N N     . PRO A 1 872  ? 200.144 326.939 257.811 1.00 98.74  ? 872  PRO A N     1 
ATOM   5759  C CA    . PRO A 1 872  ? 200.462 325.632 257.223 1.00 98.74  ? 872  PRO A CA    1 
ATOM   5760  C C     . PRO A 1 872  ? 199.303 325.097 256.395 1.00 98.74  ? 872  PRO A C     1 
ATOM   5761  O O     . PRO A 1 872  ? 198.187 325.621 256.405 1.00 98.74  ? 872  PRO A O     1 
ATOM   5762  C CB    . PRO A 1 872  ? 200.739 324.743 258.442 1.00 98.74  ? 872  PRO A CB    1 
ATOM   5763  C CG    . PRO A 1 872  ? 201.035 325.690 259.557 1.00 98.74  ? 872  PRO A CG    1 
ATOM   5764  C CD    . PRO A 1 872  ? 200.229 326.921 259.282 1.00 98.74  ? 872  PRO A CD    1 
ATOM   5765  N N     . TYR A 1 873  ? 199.594 324.023 255.655 1.00 94.54  ? 873  TYR A N     1 
ATOM   5766  C CA    . TYR A 1 873  ? 198.589 323.429 254.779 1.00 94.54  ? 873  TYR A CA    1 
ATOM   5767  C C     . TYR A 1 873  ? 197.400 322.903 255.574 1.00 94.54  ? 873  TYR A C     1 
ATOM   5768  O O     . TYR A 1 873  ? 196.244 323.087 255.171 1.00 94.54  ? 873  TYR A O     1 
ATOM   5769  C CB    . TYR A 1 873  ? 199.221 322.310 253.950 1.00 94.54  ? 873  TYR A CB    1 
ATOM   5770  C CG    . TYR A 1 873  ? 198.460 321.960 252.691 1.00 94.54  ? 873  TYR A CG    1 
ATOM   5771  C CD1   . TYR A 1 873  ? 197.390 321.074 252.725 1.00 94.54  ? 873  TYR A CD1   1 
ATOM   5772  C CD2   . TYR A 1 873  ? 198.812 322.514 251.467 1.00 94.54  ? 873  TYR A CD2   1 
ATOM   5773  C CE1   . TYR A 1 873  ? 196.694 320.750 251.575 1.00 94.54  ? 873  TYR A CE1   1 
ATOM   5774  C CE2   . TYR A 1 873  ? 198.121 322.197 250.313 1.00 94.54  ? 873  TYR A CE2   1 
ATOM   5775  C CZ    . TYR A 1 873  ? 197.063 321.315 250.373 1.00 94.54  ? 873  TYR A CZ    1 
ATOM   5776  O OH    . TYR A 1 873  ? 196.372 320.997 249.226 1.00 94.54  ? 873  TYR A OH    1 
ATOM   5777  N N     . GLU A 1 874  ? 197.662 322.244 256.706 1.00 98.65  ? 874  GLU A N     1 
ATOM   5778  C CA    . GLU A 1 874  ? 196.577 321.706 257.520 1.00 98.65  ? 874  GLU A CA    1 
ATOM   5779  C C     . GLU A 1 874  ? 195.686 322.818 258.061 1.00 98.65  ? 874  GLU A C     1 
ATOM   5780  O O     . GLU A 1 874  ? 194.454 322.714 258.017 1.00 98.65  ? 874  GLU A O     1 
ATOM   5781  C CB    . GLU A 1 874  ? 197.147 320.869 258.665 1.00 98.65  ? 874  GLU A CB    1 
ATOM   5782  C CG    . GLU A 1 874  ? 196.109 320.377 259.662 1.00 98.65  ? 874  GLU A CG    1 
ATOM   5783  C CD    . GLU A 1 874  ? 194.925 319.706 258.991 1.00 98.65  ? 874  GLU A CD    1 
ATOM   5784  O OE1   . GLU A 1 874  ? 195.135 318.702 258.277 1.00 98.65  ? 874  GLU A OE1   1 
ATOM   5785  O OE2   . GLU A 1 874  ? 193.785 320.179 259.180 1.00 98.65  ? 874  GLU A OE2   1 
ATOM   5786  N N     . ALA A 1 875  ? 196.290 323.894 258.573 1.00 97.97  ? 875  ALA A N     1 
ATOM   5787  C CA    . ALA A 1 875  ? 195.504 325.004 259.101 1.00 97.97  ? 875  ALA A CA    1 
ATOM   5788  C C     . ALA A 1 875  ? 194.696 325.682 258.002 1.00 97.97  ? 875  ALA A C     1 
ATOM   5789  O O     . ALA A 1 875  ? 193.530 326.042 258.210 1.00 97.97  ? 875  ALA A O     1 
ATOM   5790  C CB    . ALA A 1 875  ? 196.419 326.012 259.796 1.00 97.97  ? 875  ALA A CB    1 
ATOM   5791  N N     . LEU A 1 876  ? 195.300 325.867 256.826 1.00 95.05  ? 876  LEU A N     1 
ATOM   5792  C CA    . LEU A 1 876  ? 194.581 326.475 255.711 1.00 95.05  ? 876  LEU A CA    1 
ATOM   5793  C C     . LEU A 1 876  ? 193.397 325.617 255.284 1.00 95.05  ? 876  LEU A C     1 
ATOM   5794  O O     . LEU A 1 876  ? 192.299 326.135 255.044 1.00 95.05  ? 876  LEU A O     1 
ATOM   5795  C CB    . LEU A 1 876  ? 195.534 326.696 254.536 1.00 95.05  ? 876  LEU A CB    1 
ATOM   5796  C CG    . LEU A 1 876  ? 194.915 327.227 253.242 1.00 95.05  ? 876  LEU A CG    1 
ATOM   5797  C CD1   . LEU A 1 876  ? 194.305 328.604 253.460 1.00 95.05  ? 876  LEU A CD1   1 
ATOM   5798  C CD2   . LEU A 1 876  ? 195.949 327.259 252.127 1.00 95.05  ? 876  LEU A CD2   1 
ATOM   5799  N N     . THR A 1 877  ? 193.599 324.300 255.189 1.00 95.67  ? 877  THR A N     1 
ATOM   5800  C CA    . THR A 1 877  ? 192.505 323.410 254.815 1.00 95.67  ? 877  THR A CA    1 
ATOM   5801  C C     . THR A 1 877  ? 191.402 323.419 255.865 1.00 95.67  ? 877  THR A C     1 
ATOM   5802  O O     . THR A 1 877  ? 190.213 323.413 255.526 1.00 95.67  ? 877  THR A O     1 
ATOM   5803  C CB    . THR A 1 877  ? 193.028 321.990 254.600 1.00 95.67  ? 877  THR A CB    1 
ATOM   5804  O OG1   . THR A 1 877  ? 193.895 321.628 255.682 1.00 95.67  ? 877  THR A OG1   1 
ATOM   5805  C CG2   . THR A 1 877  ? 193.793 321.898 253.289 1.00 95.67  ? 877  THR A CG2   1 
ATOM   5806  N N     . GLN A 1 878  ? 191.777 323.428 257.148 1.00 100.52 ? 878  GLN A N     1 
ATOM   5807  C CA    . GLN A 1 878  ? 190.777 323.474 258.209 1.00 100.52 ? 878  GLN A CA    1 
ATOM   5808  C C     . GLN A 1 878  ? 189.970 324.765 258.148 1.00 100.52 ? 878  GLN A C     1 
ATOM   5809  O O     . GLN A 1 878  ? 188.743 324.747 258.300 1.00 100.52 ? 878  GLN A O     1 
ATOM   5810  C CB    . GLN A 1 878  ? 191.453 323.318 259.572 1.00 100.52 ? 878  GLN A CB    1 
ATOM   5811  C CG    . GLN A 1 878  ? 190.822 324.135 260.690 1.00 100.52 ? 878  GLN A CG    1 
ATOM   5812  C CD    . GLN A 1 878  ? 191.415 323.820 262.048 1.00 100.52 ? 878  GLN A CD    1 
ATOM   5813  O OE1   . GLN A 1 878  ? 191.774 322.677 262.332 1.00 100.52 ? 878  GLN A OE1   1 
ATOM   5814  N NE2   . GLN A 1 878  ? 191.522 324.835 262.898 1.00 100.52 ? 878  GLN A NE2   1 
ATOM   5815  N N     . LEU A 1 879  ? 190.641 325.897 257.916 1.00 94.43  ? 879  LEU A N     1 
ATOM   5816  C CA    . LEU A 1 879  ? 189.933 327.169 257.807 1.00 94.43  ? 879  LEU A CA    1 
ATOM   5817  C C     . LEU A 1 879  ? 189.001 327.179 256.601 1.00 94.43  ? 879  LEU A C     1 
ATOM   5818  O O     . LEU A 1 879  ? 187.867 327.670 256.687 1.00 94.43  ? 879  LEU A O     1 
ATOM   5819  C CB    . LEU A 1 879  ? 190.933 328.321 257.723 1.00 94.43  ? 879  LEU A CB    1 
ATOM   5820  C CG    . LEU A 1 879  ? 190.535 329.620 258.428 1.00 94.43  ? 879  LEU A CG    1 
ATOM   5821  C CD1   . LEU A 1 879  ? 190.067 329.342 259.848 1.00 94.43  ? 879  LEU A CD1   1 
ATOM   5822  C CD2   . LEU A 1 879  ? 191.691 330.609 258.424 1.00 94.43  ? 879  LEU A CD2   1 
ATOM   5823  N N     . ILE A 1 880  ? 189.460 326.640 255.468 1.00 95.95  ? 880  ILE A N     1 
ATOM   5824  C CA    . ILE A 1 880  ? 188.621 326.592 254.273 1.00 95.95  ? 880  ILE A CA    1 
ATOM   5825  C C     . ILE A 1 880  ? 187.390 325.730 254.519 1.00 95.95  ? 880  ILE A C     1 
ATOM   5826  O O     . ILE A 1 880  ? 186.269 326.103 254.152 1.00 95.95  ? 880  ILE A O     1 
ATOM   5827  C CB    . ILE A 1 880  ? 189.437 326.090 253.067 1.00 95.95  ? 880  ILE A CB    1 
ATOM   5828  C CG1   . ILE A 1 880  ? 190.404 327.174 252.589 1.00 95.95  ? 880  ILE A CG1   1 
ATOM   5829  C CG2   . ILE A 1 880  ? 188.516 325.662 251.934 1.00 95.95  ? 880  ILE A CG2   1 
ATOM   5830  C CD1   . ILE A 1 880  ? 191.550 326.644 251.757 1.00 95.95  ? 880  ILE A CD1   1 
ATOM   5831  N N     . ASP A 1 881  ? 187.576 324.564 255.146 1.00 101.94 ? 881  ASP A N     1 
ATOM   5832  C CA    . ASP A 1 881  ? 186.443 323.691 255.438 1.00 101.94 ? 881  ASP A CA    1 
ATOM   5833  C C     . ASP A 1 881  ? 185.470 324.350 256.408 1.00 101.94 ? 881  ASP A C     1 
ATOM   5834  O O     . ASP A 1 881  ? 184.249 324.246 256.238 1.00 101.94 ? 881  ASP A O     1 
ATOM   5835  C CB    . ASP A 1 881  ? 186.938 322.357 255.996 1.00 101.94 ? 881  ASP A CB    1 
ATOM   5836  C CG    . ASP A 1 881  ? 187.803 321.597 255.010 1.00 101.94 ? 881  ASP A CG    1 
ATOM   5837  O OD1   . ASP A 1 881  ? 187.854 322.000 253.829 1.00 101.94 ? 881  ASP A OD1   1 
ATOM   5838  O OD2   . ASP A 1 881  ? 188.433 320.598 255.416 1.00 101.94 ? 881  ASP A OD2   1 
ATOM   5839  N N     . GLU A 1 882  ? 185.990 325.029 257.434 1.00 100.50 ? 882  GLU A N     1 
ATOM   5840  C CA    . GLU A 1 882  ? 185.120 325.706 258.390 1.00 100.50 ? 882  GLU A CA    1 
ATOM   5841  C C     . GLU A 1 882  ? 184.317 326.812 257.718 1.00 100.50 ? 882  GLU A C     1 
ATOM   5842  O O     . GLU A 1 882  ? 183.125 326.984 258.001 1.00 100.50 ? 882  GLU A O     1 
ATOM   5843  C CB    . GLU A 1 882  ? 185.947 326.269 259.546 1.00 100.50 ? 882  GLU A CB    1 
ATOM   5844  C CG    . GLU A 1 882  ? 185.142 326.556 260.803 1.00 100.50 ? 882  GLU A CG    1 
ATOM   5845  C CD    . GLU A 1 882  ? 185.743 327.670 261.638 1.00 100.50 ? 882  GLU A CD    1 
ATOM   5846  O OE1   . GLU A 1 882  ? 185.818 328.813 261.141 1.00 100.50 ? 882  GLU A OE1   1 
ATOM   5847  O OE2   . GLU A 1 882  ? 186.139 327.402 262.792 1.00 100.50 ? 882  GLU A OE2   1 
ATOM   5848  N N     . ALA A 1 883  ? 184.955 327.578 256.830 1.00 102.98 ? 883  ALA A N     1 
ATOM   5849  C CA    . ALA A 1 883  ? 184.235 328.619 256.102 1.00 102.98 ? 883  ALA A CA    1 
ATOM   5850  C C     . ALA A 1 883  ? 183.182 328.021 255.178 1.00 102.98 ? 883  ALA A C     1 
ATOM   5851  O O     . ALA A 1 883  ? 182.073 328.556 255.059 1.00 102.98 ? 883  ALA A O     1 
ATOM   5852  C CB    . ALA A 1 883  ? 185.217 329.481 255.311 1.00 102.98 ? 883  ALA A CB    1 
ATOM   5853  N N     . SER A 1 884  ? 183.511 326.912 254.512 1.00 108.02 ? 884  SER A N     1 
ATOM   5854  C CA    . SER A 1 884  ? 182.574 326.306 253.571 1.00 108.02 ? 884  SER A CA    1 
ATOM   5855  C C     . SER A 1 884  ? 181.382 325.687 254.289 1.00 108.02 ? 884  SER A C     1 
ATOM   5856  O O     . SER A 1 884  ? 180.273 325.649 253.742 1.00 108.02 ? 884  SER A O     1 
ATOM   5857  C CB    . SER A 1 884  ? 183.290 325.257 252.721 1.00 108.02 ? 884  SER A CB    1 
ATOM   5858  O OG    . SER A 1 884  ? 183.532 324.076 253.466 1.00 108.02 ? 884  SER A OG    1 
ATOM   5859  N N     . GLU A 1 885  ? 181.597 325.177 255.505 1.00 108.83 ? 885  GLU A N     1 
ATOM   5860  C CA    . GLU A 1 885  ? 180.543 324.554 256.301 1.00 108.83 ? 885  GLU A CA    1 
ATOM   5861  C C     . GLU A 1 885  ? 179.993 323.326 255.584 1.00 108.83 ? 885  GLU A C     1 
ATOM   5862  O O     . GLU A 1 885  ? 180.756 322.549 255.000 1.00 108.83 ? 885  GLU A O     1 
ATOM   5863  C CB    . GLU A 1 885  ? 179.425 325.555 256.612 1.00 108.83 ? 885  GLU A CB    1 
ATOM   5864  C CG    . GLU A 1 885  ? 178.777 325.370 257.976 1.00 108.83 ? 885  GLU A CG    1 
ATOM   5865  C CD    . GLU A 1 885  ? 177.421 326.042 258.071 1.00 108.83 ? 885  GLU A CD    1 
ATOM   5866  O OE1   . GLU A 1 885  ? 177.180 327.007 257.316 1.00 108.83 ? 885  GLU A OE1   1 
ATOM   5867  O OE2   . GLU A 1 885  ? 176.596 325.604 258.900 1.00 108.83 ? 885  GLU A OE2   1 
ATOM   5868  N N     . GLY A 1 886  ? 178.676 323.140 255.622 1.00 108.90 ? 886  GLY A N     1 
ATOM   5869  C CA    . GLY A 1 886  ? 178.045 321.995 255.000 1.00 108.90 ? 886  GLY A CA    1 
ATOM   5870  C C     . GLY A 1 886  ? 177.806 322.099 253.512 1.00 108.90 ? 886  GLY A C     1 
ATOM   5871  O O     . GLY A 1 886  ? 177.286 321.154 252.913 1.00 108.90 ? 886  GLY A O     1 
ATOM   5872  N N     . ASP A 1 887  ? 178.168 323.224 252.891 1.00 104.24 ? 887  ASP A N     1 
ATOM   5873  C CA    . ASP A 1 887  ? 177.939 323.383 251.458 1.00 104.24 ? 887  ASP A CA    1 
ATOM   5874  C C     . ASP A 1 887  ? 178.882 322.518 250.632 1.00 104.24 ? 887  ASP A C     1 
ATOM   5875  O O     . ASP A 1 887  ? 178.588 322.228 249.466 1.00 104.24 ? 887  ASP A O     1 
ATOM   5876  C CB    . ASP A 1 887  ? 178.083 324.852 251.064 1.00 104.24 ? 887  ASP A CB    1 
ATOM   5877  C CG    . ASP A 1 887  ? 177.003 325.305 250.102 1.00 104.24 ? 887  ASP A CG    1 
ATOM   5878  O OD1   . ASP A 1 887  ? 176.657 324.529 249.186 1.00 104.24 ? 887  ASP A OD1   1 
ATOM   5879  O OD2   . ASP A 1 887  ? 176.499 326.437 250.261 1.00 104.24 ? 887  ASP A OD2   1 
ATOM   5880  N N     . MET A 1 888  ? 180.021 322.122 251.206 1.00 100.42 ? 888  MET A N     1 
ATOM   5881  C CA    . MET A 1 888  ? 180.968 321.204 250.577 1.00 100.42 ? 888  MET A CA    1 
ATOM   5882  C C     . MET A 1 888  ? 181.585 321.790 249.310 1.00 100.42 ? 888  MET A C     1 
ATOM   5883  O O     . MET A 1 888  ? 182.790 322.058 249.271 1.00 100.42 ? 888  MET A O     1 
ATOM   5884  C CB    . MET A 1 888  ? 180.294 319.863 250.269 1.00 100.42 ? 888  MET A CB    1 
ATOM   5885  C CG    . MET A 1 888  ? 181.265 318.735 249.975 1.00 100.42 ? 888  MET A CG    1 
ATOM   5886  S SD    . MET A 1 888  ? 180.673 317.134 250.556 1.00 100.42 ? 888  MET A SD    1 
ATOM   5887  C CE    . MET A 1 888  ? 181.663 316.923 252.034 1.00 100.42 ? 888  MET A CE    1 
ATOM   5888  N N     . SER A 1 889  ? 180.771 321.986 248.269 1.00 92.60  ? 889  SER A N     1 
ATOM   5889  C CA    . SER A 1 889  ? 181.284 322.506 247.004 1.00 92.60  ? 889  SER A CA    1 
ATOM   5890  C C     . SER A 1 889  ? 181.800 323.933 247.128 1.00 92.60  ? 889  SER A C     1 
ATOM   5891  O O     . SER A 1 889  ? 182.569 324.381 246.266 1.00 92.60  ? 889  SER A O     1 
ATOM   5892  C CB    . SER A 1 889  ? 180.197 322.437 245.930 1.00 92.60  ? 889  SER A CB    1 
ATOM   5893  O OG    . SER A 1 889  ? 179.105 323.279 246.254 1.00 92.60  ? 889  SER A OG    1 
ATOM   5894  N N     . ILE A 1 890  ? 181.393 324.658 248.173 1.00 88.48  ? 890  ILE A N     1 
ATOM   5895  C CA    . ILE A 1 890  ? 181.890 326.015 248.378 1.00 88.48  ? 890  ILE A CA    1 
ATOM   5896  C C     . ILE A 1 890  ? 183.397 326.000 248.599 1.00 88.48  ? 890  ILE A C     1 
ATOM   5897  O O     . ILE A 1 890  ? 184.117 326.882 248.118 1.00 88.48  ? 890  ILE A O     1 
ATOM   5898  C CB    . ILE A 1 890  ? 181.142 326.687 249.545 1.00 88.48  ? 890  ILE A CB    1 
ATOM   5899  C CG1   . ILE A 1 890  ? 179.806 327.256 249.060 1.00 88.48  ? 890  ILE A CG1   1 
ATOM   5900  C CG2   . ILE A 1 890  ? 181.990 327.777 250.190 1.00 88.48  ? 890  ILE A CG2   1 
ATOM   5901  C CD1   . ILE A 1 890  ? 179.929 328.577 248.330 1.00 88.48  ? 890  ILE A CD1   1 
ATOM   5902  N N     . SER A 1 891  ? 183.900 324.991 249.315 1.00 85.62  ? 891  SER A N     1 
ATOM   5903  C CA    . SER A 1 891  ? 185.342 324.872 249.513 1.00 85.62  ? 891  SER A CA    1 
ATOM   5904  C C     . SER A 1 891  ? 186.067 324.661 248.189 1.00 85.62  ? 891  SER A C     1 
ATOM   5905  O O     . SER A 1 891  ? 187.122 325.259 247.948 1.00 85.62  ? 891  SER A O     1 
ATOM   5906  C CB    . SER A 1 891  ? 185.648 323.726 250.478 1.00 85.62  ? 891  SER A CB    1 
ATOM   5907  O OG    . SER A 1 891  ? 186.876 323.099 250.152 1.00 85.62  ? 891  SER A OG    1 
ATOM   5908  N N     . ILE A 1 892  ? 185.516 323.811 247.318 1.00 81.09  ? 892  ILE A N     1 
ATOM   5909  C CA    . ILE A 1 892  ? 186.142 323.559 246.022 1.00 81.09  ? 892  ILE A CA    1 
ATOM   5910  C C     . ILE A 1 892  ? 186.141 324.824 245.173 1.00 81.09  ? 892  ILE A C     1 
ATOM   5911  O O     . ILE A 1 892  ? 187.143 325.158 244.525 1.00 81.09  ? 892  ILE A O     1 
ATOM   5912  C CB    . ILE A 1 892  ? 185.433 322.394 245.307 1.00 81.09  ? 892  ILE A CB    1 
ATOM   5913  C CG1   . ILE A 1 892  ? 185.559 321.109 246.128 1.00 81.09  ? 892  ILE A CG1   1 
ATOM   5914  C CG2   . ILE A 1 892  ? 186.007 322.193 243.914 1.00 81.09  ? 892  ILE A CG2   1 
ATOM   5915  C CD1   . ILE A 1 892  ? 186.987 320.728 246.452 1.00 81.09  ? 892  ILE A CD1   1 
ATOM   5916  N N     . LEU A 1 893  ? 185.018 325.548 245.161 1.00 78.73  ? 893  LEU A N     1 
ATOM   5917  C CA    . LEU A 1 893  ? 184.954 326.797 244.407 1.00 78.73  ? 893  LEU A CA    1 
ATOM   5918  C C     . LEU A 1 893  ? 185.943 327.821 244.952 1.00 78.73  ? 893  LEU A C     1 
ATOM   5919  O O     . LEU A 1 893  ? 186.597 328.536 244.182 1.00 78.73  ? 893  LEU A O     1 
ATOM   5920  C CB    . LEU A 1 893  ? 183.533 327.357 244.434 1.00 78.73  ? 893  LEU A CB    1 
ATOM   5921  C CG    . LEU A 1 893  ? 182.654 327.079 243.213 1.00 78.73  ? 893  LEU A CG    1 
ATOM   5922  C CD1   . LEU A 1 893  ? 182.412 325.586 243.043 1.00 78.73  ? 893  LEU A CD1   1 
ATOM   5923  C CD2   . LEU A 1 893  ? 181.338 327.834 243.317 1.00 78.73  ? 893  LEU A CD2   1 
ATOM   5924  N N     . THR A 1 894  ? 186.061 327.907 246.279 1.00 76.83  ? 894  THR A N     1 
ATOM   5925  C CA    . THR A 1 894  ? 187.009 328.832 246.888 1.00 76.83  ? 894  THR A CA    1 
ATOM   5926  C C     . THR A 1 894  ? 188.441 328.476 246.516 1.00 76.83  ? 894  THR A C     1 
ATOM   5927  O O     . THR A 1 894  ? 189.244 329.359 246.199 1.00 76.83  ? 894  THR A O     1 
ATOM   5928  C CB    . THR A 1 894  ? 186.830 328.837 248.408 1.00 76.83  ? 894  THR A CB    1 
ATOM   5929  O OG1   . THR A 1 894  ? 185.624 329.533 248.747 1.00 76.83  ? 894  THR A OG1   1 
ATOM   5930  C CG2   . THR A 1 894  ? 188.008 329.516 249.090 1.00 76.83  ? 894  THR A CG2   1 
ATOM   5931  N N     . GLN A 1 895  ? 188.779 327.184 246.543 1.00 79.35  ? 895  GLN A N     1 
ATOM   5932  C CA    . GLN A 1 895  ? 190.122 326.763 246.155 1.00 79.35  ? 895  GLN A CA    1 
ATOM   5933  C C     . GLN A 1 895  ? 190.402 327.088 244.692 1.00 79.35  ? 895  GLN A C     1 
ATOM   5934  O O     . GLN A 1 895  ? 191.494 327.560 244.351 1.00 79.35  ? 895  GLN A O     1 
ATOM   5935  C CB    . GLN A 1 895  ? 190.302 325.268 246.416 1.00 79.35  ? 895  GLN A CB    1 
ATOM   5936  C CG    . GLN A 1 895  ? 190.390 324.897 247.887 1.00 79.35  ? 895  GLN A CG    1 
ATOM   5937  C CD    . GLN A 1 895  ? 189.941 323.474 248.157 1.00 79.35  ? 895  GLN A CD    1 
ATOM   5938  O OE1   . GLN A 1 895  ? 188.944 323.243 248.840 1.00 79.35  ? 895  GLN A OE1   1 
ATOM   5939  N NE2   . GLN A 1 895  ? 190.677 322.510 247.617 1.00 79.35  ? 895  GLN A NE2   1 
ATOM   5940  N N     . GLU A 1 896  ? 189.425 326.843 243.814 1.00 75.12  ? 896  GLU A N     1 
ATOM   5941  C CA    . GLU A 1 896  ? 189.604 327.153 242.399 1.00 75.12  ? 896  GLU A CA    1 
ATOM   5942  C C     . GLU A 1 896  ? 189.822 328.647 242.187 1.00 75.12  ? 896  GLU A C     1 
ATOM   5943  O O     . GLU A 1 896  ? 190.726 329.059 241.450 1.00 75.12  ? 896  GLU A O     1 
ATOM   5944  C CB    . GLU A 1 896  ? 188.394 326.670 241.600 1.00 75.12  ? 896  GLU A CB    1 
ATOM   5945  C CG    . GLU A 1 896  ? 188.623 325.384 240.826 1.00 75.12  ? 896  GLU A CG    1 
ATOM   5946  C CD    . GLU A 1 896  ? 187.558 325.146 239.774 1.00 75.12  ? 896  GLU A CD    1 
ATOM   5947  O OE1   . GLU A 1 896  ? 186.530 325.856 239.795 1.00 75.12  ? 896  GLU A OE1   1 
ATOM   5948  O OE2   . GLU A 1 896  ? 187.748 324.252 238.923 1.00 75.12  ? 896  GLU A OE2   1 
ATOM   5949  N N     . ILE A 1 897  ? 189.004 329.476 242.838 1.00 68.70  ? 897  ILE A N     1 
ATOM   5950  C CA    . ILE A 1 897  ? 189.143 330.920 242.682 1.00 68.70  ? 897  ILE A CA    1 
ATOM   5951  C C     . ILE A 1 897  ? 190.479 331.392 243.241 1.00 68.70  ? 897  ILE A C     1 
ATOM   5952  O O     . ILE A 1 897  ? 191.150 332.242 242.646 1.00 68.70  ? 897  ILE A O     1 
ATOM   5953  C CB    . ILE A 1 897  ? 187.952 331.644 243.337 1.00 68.70  ? 897  ILE A CB    1 
ATOM   5954  C CG1   . ILE A 1 897  ? 186.794 331.739 242.343 1.00 68.70  ? 897  ILE A CG1   1 
ATOM   5955  C CG2   . ILE A 1 897  ? 188.352 333.030 243.824 1.00 68.70  ? 897  ILE A CG2   1 
ATOM   5956  C CD1   . ILE A 1 897  ? 185.439 331.725 242.986 1.00 68.70  ? 897  ILE A CD1   1 
ATOM   5957  N N     . MET A 1 898  ? 190.894 330.838 244.383 1.00 73.96  ? 898  MET A N     1 
ATOM   5958  C CA    . MET A 1 898  ? 192.162 331.235 244.984 1.00 73.96  ? 898  MET A CA    1 
ATOM   5959  C C     . MET A 1 898  ? 193.340 330.880 244.085 1.00 73.96  ? 898  MET A C     1 
ATOM   5960  O O     . MET A 1 898  ? 194.254 331.693 243.899 1.00 73.96  ? 898  MET A O     1 
ATOM   5961  C CB    . MET A 1 898  ? 192.314 330.578 246.356 1.00 73.96  ? 898  MET A CB    1 
ATOM   5962  C CG    . MET A 1 898  ? 193.690 330.737 246.979 1.00 73.96  ? 898  MET A CG    1 
ATOM   5963  S SD    . MET A 1 898  ? 193.634 330.749 248.781 1.00 73.96  ? 898  MET A SD    1 
ATOM   5964  C CE    . MET A 1 898  ? 192.242 329.666 249.092 1.00 73.96  ? 898  MET A CE    1 
ATOM   5965  N N     . VAL A 1 899  ? 193.339 329.671 243.516 1.00 66.04  ? 899  VAL A N     1 
ATOM   5966  C CA    . VAL A 1 899  ? 194.455 329.277 242.662 1.00 66.04  ? 899  VAL A CA    1 
ATOM   5967  C C     . VAL A 1 899  ? 194.453 330.090 241.371 1.00 66.04  ? 899  VAL A C     1 
ATOM   5968  O O     . VAL A 1 899  ? 195.517 330.466 240.863 1.00 66.04  ? 899  VAL A O     1 
ATOM   5969  C CB    . VAL A 1 899  ? 194.443 327.756 242.399 1.00 66.04  ? 899  VAL A CB    1 
ATOM   5970  C CG1   . VAL A 1 899  ? 193.253 327.336 241.557 1.00 66.04  ? 899  VAL A CG1   1 
ATOM   5971  C CG2   . VAL A 1 899  ? 195.747 327.322 241.739 1.00 66.04  ? 899  VAL A CG2   1 
ATOM   5972  N N     . TYR A 1 900  ? 193.269 330.399 240.829 1.00 63.92  ? 900  TYR A N     1 
ATOM   5973  C CA    . TYR A 1 900  ? 193.211 331.256 239.648 1.00 63.92  ? 900  TYR A CA    1 
ATOM   5974  C C     . TYR A 1 900  ? 193.745 332.652 239.950 1.00 63.92  ? 900  TYR A C     1 
ATOM   5975  O O     . TYR A 1 900  ? 194.488 333.229 239.146 1.00 63.92  ? 900  TYR A O     1 
ATOM   5976  C CB    . TYR A 1 900  ? 191.778 331.334 239.117 1.00 63.92  ? 900  TYR A CB    1 
ATOM   5977  C CG    . TYR A 1 900  ? 191.243 330.027 238.576 1.00 63.92  ? 900  TYR A CG    1 
ATOM   5978  C CD1   . TYR A 1 900  ? 192.102 329.046 238.097 1.00 63.92  ? 900  TYR A CD1   1 
ATOM   5979  C CD2   . TYR A 1 900  ? 189.877 329.778 238.534 1.00 63.92  ? 900  TYR A CD2   1 
ATOM   5980  C CE1   . TYR A 1 900  ? 191.616 327.851 237.599 1.00 63.92  ? 900  TYR A CE1   1 
ATOM   5981  C CE2   . TYR A 1 900  ? 189.382 328.587 238.038 1.00 63.92  ? 900  TYR A CE2   1 
ATOM   5982  C CZ    . TYR A 1 900  ? 190.255 327.627 237.572 1.00 63.92  ? 900  TYR A CZ    1 
ATOM   5983  O OH    . TYR A 1 900  ? 189.767 326.440 237.077 1.00 63.92  ? 900  TYR A OH    1 
ATOM   5984  N N     . LEU A 1 901  ? 193.375 333.212 241.106 1.00 68.91  ? 901  LEU A N     1 
ATOM   5985  C CA    . LEU A 1 901  ? 193.862 334.535 241.482 1.00 68.91  ? 901  LEU A CA    1 
ATOM   5986  C C     . LEU A 1 901  ? 195.375 334.532 241.657 1.00 68.91  ? 901  LEU A C     1 
ATOM   5987  O O     . LEU A 1 901  ? 196.064 335.453 241.202 1.00 68.91  ? 901  LEU A O     1 
ATOM   5988  C CB    . LEU A 1 901  ? 193.181 335.001 242.770 1.00 68.91  ? 901  LEU A CB    1 
ATOM   5989  C CG    . LEU A 1 901  ? 191.685 335.330 242.729 1.00 68.91  ? 901  LEU A CG    1 
ATOM   5990  C CD1   . LEU A 1 901  ? 191.259 336.073 243.989 1.00 68.91  ? 901  LEU A CD1   1 
ATOM   5991  C CD2   . LEU A 1 901  ? 191.310 336.112 241.483 1.00 68.91  ? 901  LEU A CD2   1 
ATOM   5992  N N     . ALA A 1 902  ? 195.910 333.499 242.314 1.00 72.85  ? 902  ALA A N     1 
ATOM   5993  C CA    . ALA A 1 902  ? 197.355 333.408 242.497 1.00 72.85  ? 902  ALA A CA    1 
ATOM   5994  C C     . ALA A 1 902  ? 198.073 333.272 241.161 1.00 72.85  ? 902  ALA A C     1 
ATOM   5995  O O     . ALA A 1 902  ? 199.130 333.880 240.951 1.00 72.85  ? 902  ALA A O     1 
ATOM   5996  C CB    . ALA A 1 902  ? 197.695 332.235 243.413 1.00 72.85  ? 902  ALA A CB    1 
ATOM   5997  N N     . MET A 1 903  ? 197.519 332.472 240.247 1.00 64.76  ? 903  MET A N     1 
ATOM   5998  C CA    . MET A 1 903  ? 198.137 332.305 238.936 1.00 64.76  ? 903  MET A CA    1 
ATOM   5999  C C     . MET A 1 903  ? 198.120 333.608 238.147 1.00 64.76  ? 903  MET A C     1 
ATOM   6000  O O     . MET A 1 903  ? 199.100 333.948 237.473 1.00 64.76  ? 903  MET A O     1 
ATOM   6001  C CB    . MET A 1 903  ? 197.423 331.196 238.164 1.00 64.76  ? 903  MET A CB    1 
ATOM   6002  C CG    . MET A 1 903  ? 198.231 329.918 238.044 1.00 64.76  ? 903  MET A CG    1 
ATOM   6003  S SD    . MET A 1 903  ? 197.569 328.777 236.819 1.00 64.76  ? 903  MET A SD    1 
ATOM   6004  C CE    . MET A 1 903  ? 198.254 327.234 237.415 1.00 64.76  ? 903  MET A CE    1 
ATOM   6005  N N     . TYR A 1 904  ? 197.014 334.353 238.218 1.00 67.69  ? 904  TYR A N     1 
ATOM   6006  C CA    . TYR A 1 904  ? 196.929 335.617 237.496 1.00 67.69  ? 904  TYR A CA    1 
ATOM   6007  C C     . TYR A 1 904  ? 197.750 336.718 238.154 1.00 67.69  ? 904  TYR A C     1 
ATOM   6008  O O     . TYR A 1 904  ? 198.078 337.708 237.490 1.00 67.69  ? 904  TYR A O     1 
ATOM   6009  C CB    . TYR A 1 904  ? 195.470 336.055 237.370 1.00 67.69  ? 904  TYR A CB    1 
ATOM   6010  C CG    . TYR A 1 904  ? 194.929 335.945 235.963 1.00 67.69  ? 904  TYR A CG    1 
ATOM   6011  C CD1   . TYR A 1 904  ? 195.416 336.757 234.947 1.00 67.69  ? 904  TYR A CD1   1 
ATOM   6012  C CD2   . TYR A 1 904  ? 193.940 335.023 235.648 1.00 67.69  ? 904  TYR A CD2   1 
ATOM   6013  C CE1   . TYR A 1 904  ? 194.929 336.658 233.658 1.00 67.69  ? 904  TYR A CE1   1 
ATOM   6014  C CE2   . TYR A 1 904  ? 193.446 334.917 234.362 1.00 67.69  ? 904  TYR A CE2   1 
ATOM   6015  C CZ    . TYR A 1 904  ? 193.945 335.736 233.371 1.00 67.69  ? 904  TYR A CZ    1 
ATOM   6016  O OH    . TYR A 1 904  ? 193.456 335.635 232.089 1.00 67.69  ? 904  TYR A OH    1 
ATOM   6017  N N     . MET A 1 905  ? 198.079 336.574 239.440 1.00 76.55  ? 905  MET A N     1 
ATOM   6018  C CA    . MET A 1 905  ? 198.926 337.563 240.101 1.00 76.55  ? 905  MET A CA    1 
ATOM   6019  C C     . MET A 1 905  ? 200.307 337.631 239.461 1.00 76.55  ? 905  MET A C     1 
ATOM   6020  O O     . MET A 1 905  ? 200.849 338.723 239.251 1.00 76.55  ? 905  MET A O     1 
ATOM   6021  C CB    . MET A 1 905  ? 199.047 337.239 241.590 1.00 76.55  ? 905  MET A CB    1 
ATOM   6022  C CG    . MET A 1 905  ? 199.682 338.348 242.415 1.00 76.55  ? 905  MET A CG    1 
ATOM   6023  S SD    . MET A 1 905  ? 198.492 339.590 242.947 1.00 76.55  ? 905  MET A SD    1 
ATOM   6024  C CE    . MET A 1 905  ? 199.532 340.670 243.919 1.00 76.55  ? 905  MET A CE    1 
ATOM   6025  N N     . ARG A 1 906  ? 200.894 336.475 239.146 1.00 78.89  ? 906  ARG A N     1 
ATOM   6026  C CA    . ARG A 1 906  ? 202.245 336.456 238.594 1.00 78.89  ? 906  ARG A CA    1 
ATOM   6027  C C     . ARG A 1 906  ? 202.264 336.972 237.159 1.00 78.89  ? 906  ARG A C     1 
ATOM   6028  O O     . ARG A 1 906  ? 203.158 337.736 236.776 1.00 78.89  ? 906  ARG A O     1 
ATOM   6029  C CB    . ARG A 1 906  ? 202.819 335.040 238.663 1.00 78.89  ? 906  ARG A CB    1 
ATOM   6030  C CG    . ARG A 1 906  ? 203.587 334.733 239.940 1.00 78.89  ? 906  ARG A CG    1 
ATOM   6031  C CD    . ARG A 1 906  ? 202.649 334.542 241.123 1.00 78.89  ? 906  ARG A CD    1 
ATOM   6032  N NE    . ARG A 1 906  ? 201.779 333.385 240.950 1.00 78.89  ? 906  ARG A NE    1 
ATOM   6033  C CZ    . ARG A 1 906  ? 202.159 332.126 241.117 1.00 78.89  ? 906  ARG A CZ    1 
ATOM   6034  N NH1   . ARG A 1 906  ? 203.396 331.818 241.474 1.00 78.89  ? 906  ARG A NH1   1 
ATOM   6035  N NH2   . ARG A 1 906  ? 201.277 331.150 240.924 1.00 78.89  ? 906  ARG A NH2   1 
ATOM   6036  N N     . THR A 1 907  ? 201.286 336.561 236.350 1.00 77.13  ? 907  THR A N     1 
ATOM   6037  C CA    . THR A 1 907  ? 201.292 336.922 234.935 1.00 77.13  ? 907  THR A CA    1 
ATOM   6038  C C     . THR A 1 907  ? 201.005 338.405 234.736 1.00 77.13  ? 907  THR A C     1 
ATOM   6039  O O     . THR A 1 907  ? 201.703 339.086 233.975 1.00 77.13  ? 907  THR A O     1 
ATOM   6040  C CB    . THR A 1 907  ? 200.274 336.071 234.173 1.00 77.13  ? 907  THR A CB    1 
ATOM   6041  O OG1   . THR A 1 907  ? 198.956 336.350 234.660 1.00 77.13  ? 907  THR A OG1   1 
ATOM   6042  C CG2   . THR A 1 907  ? 200.575 334.591 234.357 1.00 77.13  ? 907  THR A CG2   1 
ATOM   6043  N N     . GLN A 1 908  ? 199.982 338.926 235.411 1.00 78.01  ? 908  GLN A N     1 
ATOM   6044  C CA    . GLN A 1 908  ? 199.541 340.312 235.247 1.00 78.01  ? 908  GLN A CA    1 
ATOM   6045  C C     . GLN A 1 908  ? 199.414 340.952 236.623 1.00 78.01  ? 908  GLN A C     1 
ATOM   6046  O O     . GLN A 1 908  ? 198.313 341.028 237.187 1.00 78.01  ? 908  GLN A O     1 
ATOM   6047  C CB    . GLN A 1 908  ? 198.222 340.380 234.475 1.00 78.01  ? 908  GLN A CB    1 
ATOM   6048  C CG    . GLN A 1 908  ? 197.740 341.790 234.170 1.00 78.01  ? 908  GLN A CG    1 
ATOM   6049  C CD    . GLN A 1 908  ? 197.116 341.906 232.792 1.00 78.01  ? 908  GLN A CD    1 
ATOM   6050  O OE1   . GLN A 1 908  ? 196.478 340.972 232.307 1.00 78.01  ? 908  GLN A OE1   1 
ATOM   6051  N NE2   . GLN A 1 908  ? 197.298 343.056 232.155 1.00 78.01  ? 908  GLN A NE2   1 
ATOM   6052  N N     . PRO A 1 909  ? 200.534 341.420 237.207 1.00 80.45  ? 909  PRO A N     1 
ATOM   6053  C CA    . PRO A 1 909  ? 200.502 342.073 238.522 1.00 80.45  ? 909  PRO A CA    1 
ATOM   6054  C C     . PRO A 1 909  ? 200.158 343.561 238.455 1.00 80.45  ? 909  PRO A C     1 
ATOM   6055  O O     . PRO A 1 909  ? 200.747 344.387 239.155 1.00 80.45  ? 909  PRO A O     1 
ATOM   6056  C CB    . PRO A 1 909  ? 201.924 341.844 239.043 1.00 80.45  ? 909  PRO A CB    1 
ATOM   6057  C CG    . PRO A 1 909  ? 202.764 341.842 237.807 1.00 80.45  ? 909  PRO A CG    1 
ATOM   6058  C CD    . PRO A 1 909  ? 201.905 341.313 236.678 1.00 80.45  ? 909  PRO A CD    1 
ATOM   6059  N N     . GLY A 1 910  ? 199.191 343.902 237.608 1.00 80.97  ? 910  GLY A N     1 
ATOM   6060  C CA    . GLY A 1 910  ? 198.676 345.254 237.533 1.00 80.97  ? 910  GLY A CA    1 
ATOM   6061  C C     . GLY A 1 910  ? 197.166 345.257 237.628 1.00 80.97  ? 910  GLY A C     1 
ATOM   6062  O O     . GLY A 1 910  ? 196.543 346.280 237.926 1.00 80.97  ? 910  GLY A O     1 
ATOM   6063  N N     . LEU A 1 911  ? 196.572 344.091 237.367 1.00 83.09  ? 911  LEU A N     1 
ATOM   6064  C CA    . LEU A 1 911  ? 195.126 343.942 237.477 1.00 83.09  ? 911  LEU A CA    1 
ATOM   6065  C C     . LEU A 1 911  ? 194.662 343.999 238.926 1.00 83.09  ? 911  LEU A C     1 
ATOM   6066  O O     . LEU A 1 911  ? 193.591 344.546 239.212 1.00 83.09  ? 911  LEU A O     1 
ATOM   6067  C CB    . LEU A 1 911  ? 194.696 342.626 236.829 1.00 83.09  ? 911  LEU A CB    1 
ATOM   6068  C CG    . LEU A 1 911  ? 193.216 342.439 236.507 1.00 83.09  ? 911  LEU A CG    1 
ATOM   6069  C CD1   . LEU A 1 911  ? 193.045 341.660 235.215 1.00 83.09  ? 911  LEU A CD1   1 
ATOM   6070  C CD2   . LEU A 1 911  ? 192.538 341.721 237.654 1.00 83.09  ? 911  LEU A CD2   1 
ATOM   6071  N N     . PHE A 1 912  ? 195.446 343.444 239.846 1.00 81.06  ? 912  PHE A N     1 
ATOM   6072  C CA    . PHE A 1 912  ? 195.067 343.351 241.248 1.00 81.06  ? 912  PHE A CA    1 
ATOM   6073  C C     . PHE A 1 912  ? 195.496 344.563 242.063 1.00 81.06  ? 912  PHE A C     1 
ATOM   6074  O O     . PHE A 1 912  ? 195.302 344.570 243.283 1.00 81.06  ? 912  PHE A O     1 
ATOM   6075  C CB    . PHE A 1 912  ? 195.654 342.075 241.859 1.00 81.06  ? 912  PHE A CB    1 
ATOM   6076  C CG    . PHE A 1 912  ? 194.942 340.825 241.431 1.00 81.06  ? 912  PHE A CG    1 
ATOM   6077  C CD1   . PHE A 1 912  ? 193.570 340.824 241.256 1.00 81.06  ? 912  PHE A CD1   1 
ATOM   6078  C CD2   . PHE A 1 912  ? 195.642 339.654 241.206 1.00 81.06  ? 912  PHE A CD2   1 
ATOM   6079  C CE1   . PHE A 1 912  ? 192.912 339.679 240.863 1.00 81.06  ? 912  PHE A CE1   1 
ATOM   6080  C CE2   . PHE A 1 912  ? 194.990 338.505 240.813 1.00 81.06  ? 912  PHE A CE2   1 
ATOM   6081  C CZ    . PHE A 1 912  ? 193.623 338.519 240.640 1.00 81.06  ? 912  PHE A CZ    1 
ATOM   6082  N N     . ALA A 1 913  ? 196.073 345.578 241.426 1.00 86.26  ? 913  ALA A N     1 
ATOM   6083  C CA    . ALA A 1 913  ? 196.420 346.800 242.130 1.00 86.26  ? 913  ALA A CA    1 
ATOM   6084  C C     . ALA A 1 913  ? 195.158 347.547 242.552 1.00 86.26  ? 913  ALA A C     1 
ATOM   6085  O O     . ALA A 1 913  ? 194.055 347.281 242.067 1.00 86.26  ? 913  ALA A O     1 
ATOM   6086  C CB    . ALA A 1 913  ? 197.296 347.695 241.253 1.00 86.26  ? 913  ALA A CB    1 
ATOM   6087  N N     . GLU A 1 914  ? 195.336 348.475 243.494 1.00 86.38  ? 914  GLU A N     1 
ATOM   6088  C CA    . GLU A 1 914  ? 194.310 349.330 244.092 1.00 86.38  ? 914  GLU A CA    1 
ATOM   6089  C C     . GLU A 1 914  ? 193.337 348.554 244.975 1.00 86.38  ? 914  GLU A C     1 
ATOM   6090  O O     . GLU A 1 914  ? 192.494 349.173 245.639 1.00 86.38  ? 914  GLU A O     1 
ATOM   6091  C CB    . GLU A 1 914  ? 193.529 350.138 243.039 1.00 86.38  ? 914  GLU A CB    1 
ATOM   6092  C CG    . GLU A 1 914  ? 192.157 349.588 242.657 1.00 86.38  ? 914  GLU A CG    1 
ATOM   6093  C CD    . GLU A 1 914  ? 191.467 350.427 241.600 1.00 86.38  ? 914  GLU A CD    1 
ATOM   6094  O OE1   . GLU A 1 914  ? 192.007 351.495 241.241 1.00 86.38  ? 914  GLU A OE1   1 
ATOM   6095  O OE2   . GLU A 1 914  ? 190.385 350.020 241.128 1.00 86.38  ? 914  GLU A OE2   1 
ATOM   6096  N N     . MET A 1 915  ? 193.450 347.231 245.045 1.00 82.44  ? 915  MET A N     1 
ATOM   6097  C CA    . MET A 1 915  ? 192.613 346.404 245.904 1.00 82.44  ? 915  MET A CA    1 
ATOM   6098  C C     . MET A 1 915  ? 193.428 345.948 247.105 1.00 82.44  ? 915  MET A C     1 
ATOM   6099  O O     . MET A 1 915  ? 194.527 345.406 246.945 1.00 82.44  ? 915  MET A O     1 
ATOM   6100  C CB    . MET A 1 915  ? 192.070 345.193 245.142 1.00 82.44  ? 915  MET A CB    1 
ATOM   6101  C CG    . MET A 1 915  ? 190.553 345.132 245.065 1.00 82.44  ? 915  MET A CG    1 
ATOM   6102  S SD    . MET A 1 915  ? 189.960 343.611 244.301 1.00 82.44  ? 915  MET A SD    1 
ATOM   6103  C CE    . MET A 1 915  ? 189.558 344.191 242.655 1.00 82.44  ? 915  MET A CE    1 
ATOM   6104  N N     . PHE A 1 916  ? 192.890 346.168 248.303 1.00 91.60  ? 916  PHE A N     1 
ATOM   6105  C CA    . PHE A 1 916  ? 193.588 345.821 249.535 1.00 91.60  ? 916  PHE A CA    1 
ATOM   6106  C C     . PHE A 1 916  ? 193.194 344.460 250.089 1.00 91.60  ? 916  PHE A C     1 
ATOM   6107  O O     . PHE A 1 916  ? 194.054 343.748 250.615 1.00 91.60  ? 916  PHE A O     1 
ATOM   6108  C CB    . PHE A 1 916  ? 193.335 346.889 250.605 1.00 91.60  ? 916  PHE A CB    1 
ATOM   6109  C CG    . PHE A 1 916  ? 194.029 346.617 251.908 1.00 91.60  ? 916  PHE A CG    1 
ATOM   6110  C CD1   . PHE A 1 916  ? 195.392 346.372 251.944 1.00 91.60  ? 916  PHE A CD1   1 
ATOM   6111  C CD2   . PHE A 1 916  ? 193.321 346.608 253.098 1.00 91.60  ? 916  PHE A CD2   1 
ATOM   6112  C CE1   . PHE A 1 916  ? 196.035 346.122 253.141 1.00 91.60  ? 916  PHE A CE1   1 
ATOM   6113  C CE2   . PHE A 1 916  ? 193.958 346.359 254.298 1.00 91.60  ? 916  PHE A CE2   1 
ATOM   6114  C CZ    . PHE A 1 916  ? 195.317 346.116 254.320 1.00 91.60  ? 916  PHE A CZ    1 
ATOM   6115  N N     . ARG A 1 917  ? 191.922 344.082 249.984 1.00 86.17  ? 917  ARG A N     1 
ATOM   6116  C CA    . ARG A 1 917  ? 191.437 342.810 250.497 1.00 86.17  ? 917  ARG A CA    1 
ATOM   6117  C C     . ARG A 1 917  ? 190.668 342.079 249.408 1.00 86.17  ? 917  ARG A C     1 
ATOM   6118  O O     . ARG A 1 917  ? 189.954 342.700 248.615 1.00 86.17  ? 917  ARG A O     1 
ATOM   6119  C CB    . ARG A 1 917  ? 190.541 343.010 251.727 1.00 86.17  ? 917  ARG A CB    1 
ATOM   6120  C CG    . ARG A 1 917  ? 189.498 344.104 251.565 1.00 86.17  ? 917  ARG A CG    1 
ATOM   6121  C CD    . ARG A 1 917  ? 188.551 344.169 252.756 1.00 86.17  ? 917  ARG A CD    1 
ATOM   6122  N NE    . ARG A 1 917  ? 189.210 344.643 253.968 1.00 86.17  ? 917  ARG A NE    1 
ATOM   6123  C CZ    . ARG A 1 917  ? 189.674 343.856 254.930 1.00 86.17  ? 917  ARG A CZ    1 
ATOM   6124  N NH1   . ARG A 1 917  ? 189.559 342.540 254.861 1.00 86.17  ? 917  ARG A NH1   1 
ATOM   6125  N NH2   . ARG A 1 917  ? 190.264 344.404 255.988 1.00 86.17  ? 917  ARG A NH2   1 
ATOM   6126  N N     . LEU A 1 918  ? 190.819 340.758 249.374 1.00 79.73  ? 918  LEU A N     1 
ATOM   6127  C CA    . LEU A 1 918  ? 190.136 339.905 248.410 1.00 79.73  ? 918  LEU A CA    1 
ATOM   6128  C C     . LEU A 1 918  ? 189.147 339.019 249.156 1.00 79.73  ? 918  LEU A C     1 
ATOM   6129  O O     . LEU A 1 918  ? 189.529 338.309 250.092 1.00 79.73  ? 918  LEU A O     1 
ATOM   6130  C CB    . LEU A 1 918  ? 191.134 339.056 247.622 1.00 79.73  ? 918  LEU A CB    1 
ATOM   6131  C CG    . LEU A 1 918  ? 192.262 339.803 246.905 1.00 79.73  ? 918  LEU A CG    1 
ATOM   6132  C CD1   . LEU A 1 918  ? 193.532 339.807 247.744 1.00 79.73  ? 918  LEU A CD1   1 
ATOM   6133  C CD2   . LEU A 1 918  ? 192.523 339.200 245.534 1.00 79.73  ? 918  LEU A CD2   1 
ATOM   6134  N N     . ARG A 1 919  ? 187.884 339.061 248.740 1.00 82.58  ? 919  ARG A N     1 
ATOM   6135  C CA    . ARG A 1 919  ? 186.816 338.285 249.361 1.00 82.58  ? 919  ARG A CA    1 
ATOM   6136  C C     . ARG A 1 919  ? 186.329 337.249 248.355 1.00 82.58  ? 919  ARG A C     1 
ATOM   6137  O O     . ARG A 1 919  ? 185.684 337.597 247.360 1.00 82.58  ? 919  ARG A O     1 
ATOM   6138  C CB    . ARG A 1 919  ? 185.676 339.194 249.816 1.00 82.58  ? 919  ARG A CB    1 
ATOM   6139  C CG    . ARG A 1 919  ? 186.122 340.348 250.699 1.00 82.58  ? 919  ARG A CG    1 
ATOM   6140  C CD    . ARG A 1 919  ? 185.408 340.331 252.040 1.00 82.58  ? 919  ARG A CD    1 
ATOM   6141  N NE    . ARG A 1 919  ? 185.932 341.345 252.948 1.00 82.58  ? 919  ARG A NE    1 
ATOM   6142  C CZ    . ARG A 1 919  ? 185.309 341.767 254.040 1.00 82.58  ? 919  ARG A CZ    1 
ATOM   6143  N NH1   . ARG A 1 919  ? 184.130 341.283 254.394 1.00 82.58  ? 919  ARG A NH1   1 
ATOM   6144  N NH2   . ARG A 1 919  ? 185.883 342.700 254.795 1.00 82.58  ? 919  ARG A NH2   1 
ATOM   6145  N N     . ILE A 1 920  ? 186.640 335.977 248.618 1.00 76.19  ? 920  ILE A N     1 
ATOM   6146  C CA    . ILE A 1 920  ? 186.253 334.910 247.699 1.00 76.19  ? 920  ILE A CA    1 
ATOM   6147  C C     . ILE A 1 920  ? 184.738 334.742 247.673 1.00 76.19  ? 920  ILE A C     1 
ATOM   6148  O O     . ILE A 1 920  ? 184.143 334.533 246.610 1.00 76.19  ? 920  ILE A O     1 
ATOM   6149  C CB    . ILE A 1 920  ? 186.966 333.591 248.059 1.00 76.19  ? 920  ILE A CB    1 
ATOM   6150  C CG1   . ILE A 1 920  ? 188.495 333.737 248.000 1.00 76.19  ? 920  ILE A CG1   1 
ATOM   6151  C CG2   . ILE A 1 920  ? 186.512 332.469 247.139 1.00 76.19  ? 920  ILE A CG2   1 
ATOM   6152  C CD1   . ILE A 1 920  ? 189.149 334.295 249.253 1.00 76.19  ? 920  ILE A CD1   1 
ATOM   6153  N N     . GLY A 1 921  ? 184.090 334.824 248.837 1.00 82.97  ? 921  GLY A N     1 
ATOM   6154  C CA    . GLY A 1 921  ? 182.642 334.680 248.875 1.00 82.97  ? 921  GLY A CA    1 
ATOM   6155  C C     . GLY A 1 921  ? 181.924 335.802 248.149 1.00 82.97  ? 921  GLY A C     1 
ATOM   6156  O O     . GLY A 1 921  ? 180.943 335.573 247.434 1.00 82.97  ? 921  GLY A O     1 
ATOM   6157  N N     . LEU A 1 922  ? 182.399 337.036 248.331 1.00 82.11  ? 922  LEU A N     1 
ATOM   6158  C CA    . LEU A 1 922  ? 181.818 338.163 247.609 1.00 82.11  ? 922  LEU A CA    1 
ATOM   6159  C C     . LEU A 1 922  ? 182.021 338.011 246.107 1.00 82.11  ? 922  LEU A C     1 
ATOM   6160  O O     . LEU A 1 922  ? 181.129 338.337 245.316 1.00 82.11  ? 922  LEU A O     1 
ATOM   6161  C CB    . LEU A 1 922  ? 182.421 339.476 248.106 1.00 82.11  ? 922  LEU A CB    1 
ATOM   6162  C CG    . LEU A 1 922  ? 181.777 340.076 249.358 1.00 82.11  ? 922  LEU A CG    1 
ATOM   6163  C CD1   . LEU A 1 922  ? 182.558 341.289 249.838 1.00 82.11  ? 922  LEU A CD1   1 
ATOM   6164  C CD2   . LEU A 1 922  ? 180.323 340.439 249.094 1.00 82.11  ? 922  LEU A CD2   1 
ATOM   6165  N N     . ILE A 1 923  ? 183.190 337.513 245.697 1.00 77.53  ? 923  ILE A N     1 
ATOM   6166  C CA    . ILE A 1 923  ? 183.441 337.263 244.280 1.00 77.53  ? 923  ILE A CA    1 
ATOM   6167  C C     . ILE A 1 923  ? 182.470 336.214 243.749 1.00 77.53  ? 923  ILE A C     1 
ATOM   6168  O O     . ILE A 1 923  ? 181.920 336.351 242.650 1.00 77.53  ? 923  ILE A O     1 
ATOM   6169  C CB    . ILE A 1 923  ? 184.907 336.846 244.060 1.00 77.53  ? 923  ILE A CB    1 
ATOM   6170  C CG1   . ILE A 1 923  ? 185.827 338.065 244.146 1.00 77.53  ? 923  ILE A CG1   1 
ATOM   6171  C CG2   . ILE A 1 923  ? 185.077 336.145 242.720 1.00 77.53  ? 923  ILE A CG2   1 
ATOM   6172  C CD1   . ILE A 1 923  ? 187.270 337.723 244.449 1.00 77.53  ? 923  ILE A CD1   1 
ATOM   6173  N N     . ILE A 1 924  ? 182.245 335.151 244.526 1.00 80.91  ? 924  ILE A N     1 
ATOM   6174  C CA    . ILE A 1 924  ? 181.310 334.104 244.119 1.00 80.91  ? 924  ILE A CA    1 
ATOM   6175  C C     . ILE A 1 924  ? 179.910 334.679 243.950 1.00 80.91  ? 924  ILE A C     1 
ATOM   6176  O O     . ILE A 1 924  ? 179.215 334.389 242.966 1.00 80.91  ? 924  ILE A O     1 
ATOM   6177  C CB    . ILE A 1 924  ? 181.326 332.951 245.143 1.00 80.91  ? 924  ILE A CB    1 
ATOM   6178  C CG1   . ILE A 1 924  ? 182.498 332.008 244.873 1.00 80.91  ? 924  ILE A CG1   1 
ATOM   6179  C CG2   . ILE A 1 924  ? 180.008 332.186 245.117 1.00 80.91  ? 924  ILE A CG2   1 
ATOM   6180  C CD1   . ILE A 1 924  ? 182.403 330.683 245.597 1.00 80.91  ? 924  ILE A CD1   1 
ATOM   6181  N N     . GLN A 1 925  ? 179.477 335.502 244.907 1.00 85.04  ? 925  GLN A N     1 
ATOM   6182  C CA    . GLN A 1 925  ? 178.155 336.113 244.818 1.00 85.04  ? 925  GLN A CA    1 
ATOM   6183  C C     . GLN A 1 925  ? 178.050 337.025 243.601 1.00 85.04  ? 925  GLN A C     1 
ATOM   6184  O O     . GLN A 1 925  ? 177.021 337.042 242.917 1.00 85.04  ? 925  GLN A O     1 
ATOM   6185  C CB    . GLN A 1 925  ? 177.845 336.886 246.100 1.00 85.04  ? 925  GLN A CB    1 
ATOM   6186  C CG    . GLN A 1 925  ? 177.227 336.037 247.199 1.00 85.04  ? 925  GLN A CG    1 
ATOM   6187  C CD    . GLN A 1 925  ? 177.272 336.714 248.554 1.00 85.04  ? 925  GLN A CD    1 
ATOM   6188  O OE1   . GLN A 1 925  ? 177.366 337.937 248.647 1.00 85.04  ? 925  GLN A OE1   1 
ATOM   6189  N NE2   . GLN A 1 925  ? 177.203 335.918 249.615 1.00 85.04  ? 925  GLN A NE2   1 
ATOM   6190  N N     . VAL A 1 926  ? 179.108 337.788 243.314 1.00 84.55  ? 926  VAL A N     1 
ATOM   6191  C CA    . VAL A 1 926  ? 179.097 338.677 242.154 1.00 84.55  ? 926  VAL A CA    1 
ATOM   6192  C C     . VAL A 1 926  ? 178.983 337.870 240.866 1.00 84.55  ? 926  VAL A C     1 
ATOM   6193  O O     . VAL A 1 926  ? 178.200 338.207 239.969 1.00 84.55  ? 926  VAL A O     1 
ATOM   6194  C CB    . VAL A 1 926  ? 180.350 339.572 242.154 1.00 84.55  ? 926  VAL A CB    1 
ATOM   6195  C CG1   . VAL A 1 926  ? 180.574 340.182 240.778 1.00 84.55  ? 926  VAL A CG1   1 
ATOM   6196  C CG2   . VAL A 1 926  ? 180.223 340.659 243.208 1.00 84.55  ? 926  VAL A CG2   1 
ATOM   6197  N N     . MET A 1 927  ? 179.765 336.792 240.755 1.00 81.47  ? 927  MET A N     1 
ATOM   6198  C CA    . MET A 1 927  ? 179.710 335.957 239.557 1.00 81.47  ? 927  MET A CA    1 
ATOM   6199  C C     . MET A 1 927  ? 178.333 335.328 239.388 1.00 81.47  ? 927  MET A C     1 
ATOM   6200  O O     . MET A 1 927  ? 177.802 335.267 238.272 1.00 81.47  ? 927  MET A O     1 
ATOM   6201  C CB    . MET A 1 927  ? 180.795 334.880 239.614 1.00 81.47  ? 927  MET A CB    1 
ATOM   6202  C CG    . MET A 1 927  ? 182.206 335.424 239.788 1.00 81.47  ? 927  MET A CG    1 
ATOM   6203  S SD    . MET A 1 927  ? 183.485 334.151 239.798 1.00 81.47  ? 927  MET A SD    1 
ATOM   6204  C CE    . MET A 1 927  ? 183.763 333.918 238.047 1.00 81.47  ? 927  MET A CE    1 
ATOM   6205  N N     . ALA A 1 928  ? 177.736 334.860 240.487 1.00 91.70  ? 928  ALA A N     1 
ATOM   6206  C CA    . ALA A 1 928  ? 176.388 334.306 240.414 1.00 91.70  ? 928  ALA A CA    1 
ATOM   6207  C C     . ALA A 1 928  ? 175.380 335.362 239.976 1.00 91.70  ? 928  ALA A C     1 
ATOM   6208  O O     . ALA A 1 928  ? 174.472 335.077 239.186 1.00 91.70  ? 928  ALA A O     1 
ATOM   6209  C CB    . ALA A 1 928  ? 175.990 333.709 241.763 1.00 91.70  ? 928  ALA A CB    1 
ATOM   6210  N N     . THR A 1 929  ? 175.521 336.589 240.486 1.00 92.38  ? 929  THR A N     1 
ATOM   6211  C CA    . THR A 1 929  ? 174.613 337.664 240.100 1.00 92.38  ? 929  THR A CA    1 
ATOM   6212  C C     . THR A 1 929  ? 174.728 337.982 238.614 1.00 92.38  ? 929  THR A C     1 
ATOM   6213  O O     . THR A 1 929  ? 173.713 338.171 237.933 1.00 92.38  ? 929  THR A O     1 
ATOM   6214  C CB    . THR A 1 929  ? 174.892 338.913 240.937 1.00 92.38  ? 929  THR A CB    1 
ATOM   6215  O OG1   . THR A 1 929  ? 174.903 338.566 242.327 1.00 92.38  ? 929  THR A OG1   1 
ATOM   6216  C CG2   . THR A 1 929  ? 173.824 339.969 240.693 1.00 92.38  ? 929  THR A CG2   1 
ATOM   6217  N N     . GLU A 1 930  ? 175.956 338.048 238.092 1.00 96.00  ? 930  GLU A N     1 
ATOM   6218  C CA    . GLU A 1 930  ? 176.125 338.304 236.663 1.00 96.00  ? 930  GLU A CA    1 
ATOM   6219  C C     . GLU A 1 930  ? 175.591 337.154 235.819 1.00 96.00  ? 930  GLU A C     1 
ATOM   6220  O O     . GLU A 1 930  ? 175.022 337.383 234.746 1.00 96.00  ? 930  GLU A O     1 
ATOM   6221  C CB    . GLU A 1 930  ? 177.589 338.589 236.324 1.00 96.00  ? 930  GLU A CB    1 
ATOM   6222  C CG    . GLU A 1 930  ? 178.333 339.509 237.283 1.00 96.00  ? 930  GLU A CG    1 
ATOM   6223  C CD    . GLU A 1 930  ? 177.632 340.840 237.527 1.00 96.00  ? 930  GLU A CD    1 
ATOM   6224  O OE1   . GLU A 1 930  ? 176.570 340.868 238.185 1.00 96.00  ? 930  GLU A OE1   1 
ATOM   6225  O OE2   . GLU A 1 930  ? 178.146 341.867 237.039 1.00 96.00  ? 930  GLU A OE2   1 
ATOM   6226  N N     . LEU A 1 931  ? 175.773 335.912 236.273 1.00 98.64  ? 931  LEU A N     1 
ATOM   6227  C CA    . LEU A 1 931  ? 175.198 334.784 235.542 1.00 98.64  ? 931  LEU A CA    1 
ATOM   6228  C C     . LEU A 1 931  ? 173.677 334.869 235.509 1.00 98.64  ? 931  LEU A C     1 
ATOM   6229  O O     . LEU A 1 931  ? 173.056 334.641 234.462 1.00 98.64  ? 931  LEU A O     1 
ATOM   6230  C CB    . LEU A 1 931  ? 175.649 333.461 236.161 1.00 98.64  ? 931  LEU A CB    1 
ATOM   6231  C CG    . LEU A 1 931  ? 176.891 332.802 235.556 1.00 98.64  ? 931  LEU A CG    1 
ATOM   6232  C CD1   . LEU A 1 931  ? 176.532 332.095 234.259 1.00 98.64  ? 931  LEU A CD1   1 
ATOM   6233  C CD2   . LEU A 1 931  ? 177.980 333.826 235.311 1.00 98.64  ? 931  LEU A CD2   1 
ATOM   6234  N N     . ALA A 1 932  ? 173.061 335.207 236.644 1.00 105.87 ? 932  ALA A N     1 
ATOM   6235  C CA    . ALA A 1 932  ? 171.610 335.353 236.684 1.00 105.87 ? 932  ALA A CA    1 
ATOM   6236  C C     . ALA A 1 932  ? 171.144 336.483 235.776 1.00 105.87 ? 932  ALA A C     1 
ATOM   6237  O O     . ALA A 1 932  ? 170.127 336.355 235.085 1.00 105.87 ? 932  ALA A O     1 
ATOM   6238  C CB    . ALA A 1 932  ? 171.145 335.590 238.121 1.00 105.87 ? 932  ALA A CB    1 
ATOM   6239  N N     . HIS A 1 933  ? 171.870 337.603 235.770 1.00 106.91 ? 933  HIS A N     1 
ATOM   6240  C CA    . HIS A 1 933  ? 171.496 338.726 234.915 1.00 106.91 ? 933  HIS A CA    1 
ATOM   6241  C C     . HIS A 1 933  ? 171.625 338.369 233.438 1.00 106.91 ? 933  HIS A C     1 
ATOM   6242  O O     . HIS A 1 933  ? 170.750 338.708 232.632 1.00 106.91 ? 933  HIS A O     1 
ATOM   6243  C CB    . HIS A 1 933  ? 172.354 339.946 235.248 1.00 106.91 ? 933  HIS A CB    1 
ATOM   6244  C CG    . HIS A 1 933  ? 171.676 341.254 234.978 1.00 106.91 ? 933  HIS A CG    1 
ATOM   6245  N ND1   . HIS A 1 933  ? 172.020 342.419 235.629 1.00 106.91 ? 933  HIS A ND1   1 
ATOM   6246  C CD2   . HIS A 1 933  ? 170.674 341.580 234.128 1.00 106.91 ? 933  HIS A CD2   1 
ATOM   6247  C CE1   . HIS A 1 933  ? 171.260 343.406 235.192 1.00 106.91 ? 933  HIS A CE1   1 
ATOM   6248  N NE2   . HIS A 1 933  ? 170.435 342.924 234.280 1.00 106.91 ? 933  HIS A NE2   1 
ATOM   6249  N N     . SER A 1 934  ? 172.712 337.691 233.064 1.00 107.05 ? 934  SER A N     1 
ATOM   6250  C CA    . SER A 1 934  ? 172.928 337.347 231.662 1.00 107.05 ? 934  SER A CA    1 
ATOM   6251  C C     . SER A 1 934  ? 171.913 336.320 231.178 1.00 107.05 ? 934  SER A C     1 
ATOM   6252  O O     . SER A 1 934  ? 171.370 336.447 230.074 1.00 107.05 ? 934  SER A O     1 
ATOM   6253  C CB    . SER A 1 934  ? 174.352 336.827 231.464 1.00 107.05 ? 934  SER A CB    1 
ATOM   6254  O OG    . SER A 1 934  ? 175.296 337.882 231.538 1.00 107.05 ? 934  SER A OG    1 
ATOM   6255  N N     . LEU A 1 935  ? 171.641 335.297 231.987 1.00 110.22 ? 935  LEU A N     1 
ATOM   6256  C CA    . LEU A 1 935  ? 170.695 334.260 231.598 1.00 110.22 ? 935  LEU A CA    1 
ATOM   6257  C C     . LEU A 1 935  ? 169.252 334.607 231.939 1.00 110.22 ? 935  LEU A C     1 
ATOM   6258  O O     . LEU A 1 935  ? 168.346 333.879 231.518 1.00 110.22 ? 935  LEU A O     1 
ATOM   6259  C CB    . LEU A 1 935  ? 171.070 332.928 232.258 1.00 110.22 ? 935  LEU A CB    1 
ATOM   6260  C CG    . LEU A 1 935  ? 172.510 332.455 232.054 1.00 110.22 ? 935  LEU A CG    1 
ATOM   6261  C CD1   . LEU A 1 935  ? 172.729 331.099 232.708 1.00 110.22 ? 935  LEU A CD1   1 
ATOM   6262  C CD2   . LEU A 1 935  ? 172.856 332.401 230.573 1.00 110.22 ? 935  LEU A CD2   1 
ATOM   6263  N N     . ARG A 1 936  ? 169.021 335.697 232.675 1.00 110.19 ? 936  ARG A N     1 
ATOM   6264  C CA    . ARG A 1 936  ? 167.677 336.110 233.086 1.00 110.19 ? 936  ARG A CA    1 
ATOM   6265  C C     . ARG A 1 936  ? 166.945 334.972 233.793 1.00 110.19 ? 936  ARG A C     1 
ATOM   6266  O O     . ARG A 1 936  ? 165.753 334.739 233.578 1.00 110.19 ? 936  ARG A O     1 
ATOM   6267  C CB    . ARG A 1 936  ? 166.872 336.630 231.893 1.00 110.19 ? 936  ARG A CB    1 
ATOM   6268  C CG    . ARG A 1 936  ? 167.610 337.665 231.059 1.00 110.19 ? 936  ARG A CG    1 
ATOM   6269  C CD    . ARG A 1 936  ? 166.666 338.411 230.130 1.00 110.19 ? 936  ARG A CD    1 
ATOM   6270  N NE    . ARG A 1 936  ? 167.307 339.570 229.522 1.00 110.19 ? 936  ARG A NE    1 
ATOM   6271  C CZ    . ARG A 1 936  ? 166.659 340.541 228.894 1.00 110.19 ? 936  ARG A CZ    1 
ATOM   6272  N NH1   . ARG A 1 936  ? 165.341 340.527 228.772 1.00 110.19 ? 936  ARG A NH1   1 
ATOM   6273  N NH2   . ARG A 1 936  ? 167.349 341.553 228.376 1.00 110.19 ? 936  ARG A NH2   1 
ATOM   6274  N N     . CYS A 1 937  ? 167.670 334.259 234.647 1.00 112.31 ? 937  CYS A N     1 
ATOM   6275  C CA    . CYS A 1 937  ? 167.158 333.105 235.370 1.00 112.31 ? 937  CYS A CA    1 
ATOM   6276  C C     . CYS A 1 937  ? 167.199 333.376 236.872 1.00 112.31 ? 937  CYS A C     1 
ATOM   6277  O O     . CYS A 1 937  ? 167.619 334.443 237.325 1.00 112.31 ? 937  CYS A O     1 
ATOM   6278  C CB    . CYS A 1 937  ? 167.959 331.848 235.018 1.00 112.31 ? 937  CYS A CB    1 
ATOM   6279  S SG    . CYS A 1 937  ? 169.697 331.910 235.513 1.00 112.31 ? 937  CYS A SG    1 
ATOM   6280  N N     . SER A 1 938  ? 166.755 332.388 237.643 1.00 115.58 ? 938  SER A N     1 
ATOM   6281  C CA    . SER A 1 938  ? 166.724 332.502 239.091 1.00 115.58 ? 938  SER A CA    1 
ATOM   6282  C C     . SER A 1 938  ? 168.111 332.256 239.682 1.00 115.58 ? 938  SER A C     1 
ATOM   6283  O O     . SER A 1 938  ? 169.063 331.895 238.984 1.00 115.58 ? 938  SER A O     1 
ATOM   6284  C CB    . SER A 1 938  ? 165.712 331.521 239.683 1.00 115.58 ? 938  SER A CB    1 
ATOM   6285  O OG    . SER A 1 938  ? 166.238 330.206 239.719 1.00 115.58 ? 938  SER A OG    1 
ATOM   6286  N N     . ALA A 1 939  ? 168.217 332.467 240.996 1.00 114.51 ? 939  ALA A N     1 
ATOM   6287  C CA    . ALA A 1 939  ? 169.488 332.254 241.683 1.00 114.51 ? 939  ALA A CA    1 
ATOM   6288  C C     . ALA A 1 939  ? 169.904 330.789 241.637 1.00 114.51 ? 939  ALA A C     1 
ATOM   6289  O O     . ALA A 1 939  ? 171.087 330.478 241.454 1.00 114.51 ? 939  ALA A O     1 
ATOM   6290  C CB    . ALA A 1 939  ? 169.392 332.742 243.128 1.00 114.51 ? 939  ALA A CB    1 
ATOM   6291  N N     . GLU A 1 940  ? 168.947 329.874 241.814 1.00 113.85 ? 940  GLU A N     1 
ATOM   6292  C CA    . GLU A 1 940  ? 169.264 328.450 241.753 1.00 113.85 ? 940  GLU A CA    1 
ATOM   6293  C C     . GLU A 1 940  ? 169.763 328.055 240.368 1.00 113.85 ? 940  GLU A C     1 
ATOM   6294  O O     . GLU A 1 940  ? 170.735 327.301 240.241 1.00 113.85 ? 940  GLU A O     1 
ATOM   6295  C CB    . GLU A 1 940  ? 168.039 327.622 242.140 1.00 113.85 ? 940  GLU A CB    1 
ATOM   6296  C CG    . GLU A 1 940  ? 167.541 327.873 243.554 1.00 113.85 ? 940  GLU A CG    1 
ATOM   6297  C CD    . GLU A 1 940  ? 166.389 328.856 243.600 1.00 113.85 ? 940  GLU A CD    1 
ATOM   6298  O OE1   . GLU A 1 940  ? 165.382 328.628 242.897 1.00 113.85 ? 940  GLU A OE1   1 
ATOM   6299  O OE2   . GLU A 1 940  ? 166.489 329.858 244.340 1.00 113.85 ? 940  GLU A OE2   1 
ATOM   6300  N N     . GLU A 1 941  ? 169.111 328.558 239.317 1.00 115.31 ? 941  GLU A N     1 
ATOM   6301  C CA    . GLU A 1 941  ? 169.563 328.268 237.960 1.00 115.31 ? 941  GLU A CA    1 
ATOM   6302  C C     . GLU A 1 941  ? 170.941 328.864 237.700 1.00 115.31 ? 941  GLU A C     1 
ATOM   6303  O O     . GLU A 1 941  ? 171.775 328.247 237.028 1.00 115.31 ? 941  GLU A O     1 
ATOM   6304  C CB    . GLU A 1 941  ? 168.547 328.792 236.945 1.00 115.31 ? 941  GLU A CB    1 
ATOM   6305  C CG    . GLU A 1 941  ? 168.735 328.241 235.541 1.00 115.31 ? 941  GLU A CG    1 
ATOM   6306  C CD    . GLU A 1 941  ? 167.435 328.164 234.765 1.00 115.31 ? 941  GLU A CD    1 
ATOM   6307  O OE1   . GLU A 1 941  ? 166.473 328.865 235.143 1.00 115.31 ? 941  GLU A OE1   1 
ATOM   6308  O OE2   . GLU A 1 941  ? 167.375 327.404 233.776 1.00 115.31 ? 941  GLU A OE2   1 
ATOM   6309  N N     . ALA A 1 942  ? 171.195 330.067 238.220 1.00 112.48 ? 942  ALA A N     1 
ATOM   6310  C CA    . ALA A 1 942  ? 172.513 330.675 238.067 1.00 112.48 ? 942  ALA A CA    1 
ATOM   6311  C C     . ALA A 1 942  ? 173.588 329.840 238.752 1.00 112.48 ? 942  ALA A C     1 
ATOM   6312  O O     . ALA A 1 942  ? 174.674 329.636 238.198 1.00 112.48 ? 942  ALA A O     1 
ATOM   6313  C CB    . ALA A 1 942  ? 172.504 332.099 238.621 1.00 112.48 ? 942  ALA A CB    1 
ATOM   6314  N N     . THR A 1 943  ? 173.303 329.346 239.960 1.00 108.93 ? 943  THR A N     1 
ATOM   6315  C CA    . THR A 1 943  ? 174.266 328.500 240.658 1.00 108.93 ? 943  THR A CA    1 
ATOM   6316  C C     . THR A 1 943  ? 174.493 327.190 239.913 1.00 108.93 ? 943  THR A C     1 
ATOM   6317  O O     . THR A 1 943  ? 175.626 326.702 239.831 1.00 108.93 ? 943  THR A O     1 
ATOM   6318  C CB    . THR A 1 943  ? 173.796 328.228 242.087 1.00 108.93 ? 943  THR A CB    1 
ATOM   6319  O OG1   . THR A 1 943  ? 172.419 327.836 242.073 1.00 108.93 ? 943  THR A OG1   1 
ATOM   6320  C CG2   . THR A 1 943  ? 173.955 329.475 242.945 1.00 108.93 ? 943  THR A CG2   1 
ATOM   6321  N N     . GLU A 1 944  ? 173.424 326.600 239.370 1.00 109.28 ? 944  GLU A N     1 
ATOM   6322  C CA    . GLU A 1 944  ? 173.573 325.369 238.599 1.00 109.28 ? 944  GLU A CA    1 
ATOM   6323  C C     . GLU A 1 944  ? 174.426 325.597 237.357 1.00 109.28 ? 944  GLU A C     1 
ATOM   6324  O O     . GLU A 1 944  ? 175.279 324.768 237.019 1.00 109.28 ? 944  GLU A O     1 
ATOM   6325  C CB    . GLU A 1 944  ? 172.199 324.819 238.215 1.00 109.28 ? 944  GLU A CB    1 
ATOM   6326  C CG    . GLU A 1 944  ? 171.403 324.261 239.384 1.00 109.28 ? 944  GLU A CG    1 
ATOM   6327  C CD    . GLU A 1 944  ? 169.915 324.196 239.099 1.00 109.28 ? 944  GLU A CD    1 
ATOM   6328  O OE1   . GLU A 1 944  ? 169.530 324.294 237.915 1.00 109.28 ? 944  GLU A OE1   1 
ATOM   6329  O OE2   . GLU A 1 944  ? 169.131 324.049 240.060 1.00 109.28 ? 944  GLU A OE2   1 
ATOM   6330  N N     . GLY A 1 945  ? 174.209 326.716 236.664 1.00 103.66 ? 945  GLY A N     1 
ATOM   6331  C CA    . GLY A 1 945  ? 175.043 327.040 235.518 1.00 103.66 ? 945  GLY A CA    1 
ATOM   6332  C C     . GLY A 1 945  ? 176.490 327.286 235.902 1.00 103.66 ? 945  GLY A C     1 
ATOM   6333  O O     . GLY A 1 945  ? 177.409 326.905 235.173 1.00 103.66 ? 945  GLY A O     1 
ATOM   6334  N N     . LEU A 1 946  ? 176.709 327.935 237.048 1.00 98.05  ? 946  LEU A N     1 
ATOM   6335  C CA    . LEU A 1 946  ? 178.069 328.158 237.530 1.00 98.05  ? 946  LEU A CA    1 
ATOM   6336  C C     . LEU A 1 946  ? 178.764 326.833 237.821 1.00 98.05  ? 946  LEU A C     1 
ATOM   6337  O O     . LEU A 1 946  ? 179.936 326.647 237.473 1.00 98.05  ? 946  LEU A O     1 
ATOM   6338  C CB    . LEU A 1 946  ? 178.033 329.042 238.779 1.00 98.05  ? 946  LEU A CB    1 
ATOM   6339  C CG    . LEU A 1 946  ? 179.309 329.412 239.548 1.00 98.05  ? 946  LEU A CG    1 
ATOM   6340  C CD1   . LEU A 1 946  ? 180.524 329.534 238.636 1.00 98.05  ? 946  LEU A CD1   1 
ATOM   6341  C CD2   . LEU A 1 946  ? 179.100 330.696 240.340 1.00 98.05  ? 946  LEU A CD2   1 
ATOM   6342  N N     . MET A 1 947  ? 178.052 325.897 238.452 1.00 96.87  ? 947  MET A N     1 
ATOM   6343  C CA    . MET A 1 947  ? 178.620 324.573 238.692 1.00 96.87  ? 947  MET A CA    1 
ATOM   6344  C C     . MET A 1 947  ? 178.912 323.854 237.380 1.00 96.87  ? 947  MET A C     1 
ATOM   6345  O O     . MET A 1 947  ? 179.959 323.212 237.234 1.00 96.87  ? 947  MET A O     1 
ATOM   6346  C CB    . MET A 1 947  ? 177.678 323.738 239.560 1.00 96.87  ? 947  MET A CB    1 
ATOM   6347  C CG    . MET A 1 947  ? 177.389 324.330 240.930 1.00 96.87  ? 947  MET A CG    1 
ATOM   6348  S SD    . MET A 1 947  ? 178.634 323.899 242.159 1.00 96.87  ? 947  MET A SD    1 
ATOM   6349  C CE    . MET A 1 947  ? 178.603 325.360 243.194 1.00 96.87  ? 947  MET A CE    1 
ATOM   6350  N N     . ASN A 1 948  ? 177.999 323.954 236.413 1.00 85.10  ? 948  ASN A N     1 
ATOM   6351  C CA    . ASN A 1 948  ? 178.184 323.309 235.119 1.00 85.10  ? 948  ASN A CA    1 
ATOM   6352  C C     . ASN A 1 948  ? 179.245 323.986 234.262 1.00 85.10  ? 948  ASN A C     1 
ATOM   6353  O O     . ASN A 1 948  ? 179.634 323.424 233.233 1.00 85.10  ? 948  ASN A O     1 
ATOM   6354  C CB    . ASN A 1 948  ? 176.857 323.273 234.359 1.00 85.10  ? 948  ASN A CB    1 
ATOM   6355  C CG    . ASN A 1 948  ? 176.061 322.013 234.637 1.00 85.10  ? 948  ASN A CG    1 
ATOM   6356  O OD1   . ASN A 1 948  ? 174.992 322.063 235.246 1.00 85.10  ? 948  ASN A OD1   1 
ATOM   6357  N ND2   . ASN A 1 948  ? 176.580 320.875 234.192 1.00 85.10  ? 948  ASN A ND2   1 
ATOM   6358  N N     . LEU A 1 949  ? 179.714 325.169 234.651 1.00 75.92  ? 949  LEU A N     1 
ATOM   6359  C CA    . LEU A 1 949  ? 180.699 325.884 233.852 1.00 75.92  ? 949  LEU A CA    1 
ATOM   6360  C C     . LEU A 1 949  ? 182.038 325.155 233.874 1.00 75.92  ? 949  LEU A C     1 
ATOM   6361  O O     . LEU A 1 949  ? 182.473 324.650 234.912 1.00 75.92  ? 949  LEU A O     1 
ATOM   6362  C CB    . LEU A 1 949  ? 180.868 327.311 234.374 1.00 75.92  ? 949  LEU A CB    1 
ATOM   6363  C CG    . LEU A 1 949  ? 180.080 328.400 233.642 1.00 75.92  ? 949  LEU A CG    1 
ATOM   6364  C CD1   . LEU A 1 949  ? 180.412 329.777 234.201 1.00 75.92  ? 949  LEU A CD1   1 
ATOM   6365  C CD2   . LEU A 1 949  ? 180.324 328.345 232.142 1.00 75.92  ? 949  LEU A CD2   1 
ATOM   6366  N N     . SER A 1 950  ? 182.690 325.102 232.714 1.00 67.69  ? 950  SER A N     1 
ATOM   6367  C CA    . SER A 1 950  ? 183.983 324.450 232.609 1.00 67.69  ? 950  SER A CA    1 
ATOM   6368  C C     . SER A 1 950  ? 185.051 325.271 233.328 1.00 67.69  ? 950  SER A C     1 
ATOM   6369  O O     . SER A 1 950  ? 184.910 326.486 233.489 1.00 67.69  ? 950  SER A O     1 
ATOM   6370  C CB    . SER A 1 950  ? 184.363 324.260 231.142 1.00 67.69  ? 950  SER A CB    1 
ATOM   6371  O OG    . SER A 1 950  ? 185.014 325.410 230.630 1.00 67.69  ? 950  SER A OG    1 
ATOM   6372  N N     . PRO A 1 951  ? 186.125 324.621 233.792 1.00 63.42  ? 951  PRO A N     1 
ATOM   6373  C CA    . PRO A 1 951  ? 187.199 325.380 234.456 1.00 63.42  ? 951  PRO A CA    1 
ATOM   6374  C C     . PRO A 1 951  ? 187.794 326.472 233.583 1.00 63.42  ? 951  PRO A C     1 
ATOM   6375  O O     . PRO A 1 951  ? 188.111 327.556 234.088 1.00 63.42  ? 951  PRO A O     1 
ATOM   6376  C CB    . PRO A 1 951  ? 188.231 324.296 234.798 1.00 63.42  ? 951  PRO A CB    1 
ATOM   6377  C CG    . PRO A 1 951  ? 187.445 323.032 234.867 1.00 63.42  ? 951  PRO A CG    1 
ATOM   6378  C CD    . PRO A 1 951  ? 186.356 323.167 233.845 1.00 63.42  ? 951  PRO A CD    1 
ATOM   6379  N N     . SER A 1 952  ? 187.962 326.216 232.283 1.00 62.02  ? 952  SER A N     1 
ATOM   6380  C CA    . SER A 1 952  ? 188.426 327.266 231.381 1.00 62.02  ? 952  SER A CA    1 
ATOM   6381  C C     . SER A 1 952  ? 187.408 328.394 231.288 1.00 62.02  ? 952  SER A C     1 
ATOM   6382  O O     . SER A 1 952  ? 187.774 329.577 231.291 1.00 62.02  ? 952  SER A O     1 
ATOM   6383  C CB    . SER A 1 952  ? 188.713 326.683 229.998 1.00 62.02  ? 952  SER A CB    1 
ATOM   6384  O OG    . SER A 1 952  ? 189.740 327.408 229.343 1.00 62.02  ? 952  SER A OG    1 
ATOM   6385  N N     . ALA A 1 953  ? 186.123 328.045 231.204 1.00 65.06  ? 953  ALA A N     1 
ATOM   6386  C CA    . ALA A 1 953  ? 185.078 329.060 231.215 1.00 65.06  ? 953  ALA A CA    1 
ATOM   6387  C C     . ALA A 1 953  ? 185.069 329.820 232.534 1.00 65.06  ? 953  ALA A C     1 
ATOM   6388  O O     . ALA A 1 953  ? 184.851 331.036 232.554 1.00 65.06  ? 953  ALA A O     1 
ATOM   6389  C CB    . ALA A 1 953  ? 183.717 328.417 230.952 1.00 65.06  ? 953  ALA A CB    1 
ATOM   6390  N N     . MET A 1 954  ? 185.306 329.121 233.648 1.00 63.04  ? 954  MET A N     1 
ATOM   6391  C CA    . MET A 1 954  ? 185.392 329.793 234.941 1.00 63.04  ? 954  MET A CA    1 
ATOM   6392  C C     . MET A 1 954  ? 186.540 330.793 234.971 1.00 63.04  ? 954  MET A C     1 
ATOM   6393  O O     . MET A 1 954  ? 186.382 331.918 235.460 1.00 63.04  ? 954  MET A O     1 
ATOM   6394  C CB    . MET A 1 954  ? 185.556 328.762 236.058 1.00 63.04  ? 954  MET A CB    1 
ATOM   6395  C CG    . MET A 1 954  ? 185.670 329.367 237.450 1.00 63.04  ? 954  MET A CG    1 
ATOM   6396  S SD    . MET A 1 954  ? 184.111 329.385 238.353 1.00 63.04  ? 954  MET A SD    1 
ATOM   6397  C CE    . MET A 1 954  ? 183.849 327.633 238.608 1.00 63.04  ? 954  MET A CE    1 
ATOM   6398  N N     . LYS A 1 955  ? 187.707 330.400 234.453 1.00 61.26  ? 955  LYS A N     1 
ATOM   6399  C CA    . LYS A 1 955  ? 188.852 331.305 234.437 1.00 61.26  ? 955  LYS A CA    1 
ATOM   6400  C C     . LYS A 1 955  ? 188.590 332.512 233.544 1.00 61.26  ? 955  LYS A C     1 
ATOM   6401  O O     . LYS A 1 955  ? 188.915 333.647 233.911 1.00 61.26  ? 955  LYS A O     1 
ATOM   6402  C CB    . LYS A 1 955  ? 190.105 330.558 233.981 1.00 61.26  ? 955  LYS A CB    1 
ATOM   6403  C CG    . LYS A 1 955  ? 191.360 331.416 233.946 1.00 61.26  ? 955  LYS A CG    1 
ATOM   6404  C CD    . LYS A 1 955  ? 192.572 330.602 233.524 1.00 61.26  ? 955  LYS A CD    1 
ATOM   6405  C CE    . LYS A 1 955  ? 193.277 330.000 234.730 1.00 61.26  ? 955  LYS A CE    1 
ATOM   6406  N NZ    . LYS A 1 955  ? 194.560 330.695 235.030 1.00 61.26  ? 955  LYS A NZ    1 
ATOM   6407  N N     . ASN A 1 956  ? 187.999 332.286 232.367 1.00 65.97  ? 956  ASN A N     1 
ATOM   6408  C CA    . ASN A 1 956  ? 187.680 333.398 231.476 1.00 65.97  ? 956  ASN A CA    1 
ATOM   6409  C C     . ASN A 1 956  ? 186.664 334.339 232.111 1.00 65.97  ? 956  ASN A C     1 
ATOM   6410  O O     . ASN A 1 956  ? 186.788 335.565 232.004 1.00 65.97  ? 956  ASN A O     1 
ATOM   6411  C CB    . ASN A 1 956  ? 187.164 332.866 230.138 1.00 65.97  ? 956  ASN A CB    1 
ATOM   6412  C CG    . ASN A 1 956  ? 186.243 333.846 229.434 1.00 65.97  ? 956  ASN A CG    1 
ATOM   6413  O OD1   . ASN A 1 956  ? 185.031 333.847 229.652 1.00 65.97  ? 956  ASN A OD1   1 
ATOM   6414  N ND2   . ASN A 1 956  ? 186.817 334.689 228.582 1.00 65.97  ? 956  ASN A ND2   1 
ATOM   6415  N N     . LEU A 1 957  ? 185.651 333.782 232.779 1.00 64.83  ? 957  LEU A N     1 
ATOM   6416  C CA    . LEU A 1 957  ? 184.648 334.603 233.445 1.00 64.83  ? 957  LEU A CA    1 
ATOM   6417  C C     . LEU A 1 957  ? 185.262 335.419 234.574 1.00 64.83  ? 957  LEU A C     1 
ATOM   6418  O O     . LEU A 1 957  ? 184.934 336.599 234.745 1.00 64.83  ? 957  LEU A O     1 
ATOM   6419  C CB    . LEU A 1 957  ? 183.527 333.712 233.975 1.00 64.83  ? 957  LEU A CB    1 
ATOM   6420  C CG    . LEU A 1 957  ? 182.379 334.379 234.729 1.00 64.83  ? 957  LEU A CG    1 
ATOM   6421  C CD1   . LEU A 1 957  ? 181.632 335.361 233.840 1.00 64.83  ? 957  LEU A CD1   1 
ATOM   6422  C CD2   . LEU A 1 957  ? 181.449 333.314 235.278 1.00 64.83  ? 957  LEU A CD2   1 
ATOM   6423  N N     . LEU A 1 958  ? 186.148 334.806 235.362 1.00 68.11  ? 958  LEU A N     1 
ATOM   6424  C CA    . LEU A 1 958  ? 186.804 335.536 236.442 1.00 68.11  ? 958  LEU A CA    1 
ATOM   6425  C C     . LEU A 1 958  ? 187.693 336.644 235.891 1.00 68.11  ? 958  LEU A C     1 
ATOM   6426  O O     . LEU A 1 958  ? 187.736 337.748 236.446 1.00 68.11  ? 958  LEU A O     1 
ATOM   6427  C CB    . LEU A 1 958  ? 187.611 334.570 237.310 1.00 68.11  ? 958  LEU A CB    1 
ATOM   6428  C CG    . LEU A 1 958  ? 188.515 335.187 238.378 1.00 68.11  ? 958  LEU A CG    1 
ATOM   6429  C CD1   . LEU A 1 958  ? 187.687 335.974 239.382 1.00 68.11  ? 958  LEU A CD1   1 
ATOM   6430  C CD2   . LEU A 1 958  ? 189.327 334.109 239.076 1.00 68.11  ? 958  LEU A CD2   1 
ATOM   6431  N N     . HIS A 1 959  ? 188.404 336.367 234.795 1.00 71.90  ? 959  HIS A N     1 
ATOM   6432  C CA    . HIS A 1 959  ? 189.211 337.395 234.145 1.00 71.90  ? 959  HIS A CA    1 
ATOM   6433  C C     . HIS A 1 959  ? 188.346 338.555 233.669 1.00 71.90  ? 959  HIS A C     1 
ATOM   6434  O O     . HIS A 1 959  ? 188.688 339.725 233.881 1.00 71.90  ? 959  HIS A O     1 
ATOM   6435  C CB    . HIS A 1 959  ? 189.978 336.778 232.974 1.00 71.90  ? 959  HIS A CB    1 
ATOM   6436  C CG    . HIS A 1 959  ? 190.858 337.742 232.241 1.00 71.90  ? 959  HIS A CG    1 
ATOM   6437  N ND1   . HIS A 1 959  ? 192.104 338.112 232.700 1.00 71.90  ? 959  HIS A ND1   1 
ATOM   6438  C CD2   . HIS A 1 959  ? 190.675 338.404 231.074 1.00 71.90  ? 959  HIS A CD2   1 
ATOM   6439  C CE1   . HIS A 1 959  ? 192.650 338.961 231.847 1.00 71.90  ? 959  HIS A CE1   1 
ATOM   6440  N NE2   . HIS A 1 959  ? 191.803 339.157 230.854 1.00 71.90  ? 959  HIS A NE2   1 
ATOM   6441  N N     . HIS A 1 960  ? 187.211 338.247 233.037 1.00 79.59  ? 960  HIS A N     1 
ATOM   6442  C CA    . HIS A 1 960  ? 186.313 339.292 232.556 1.00 79.59  ? 960  HIS A CA    1 
ATOM   6443  C C     . HIS A 1 960  ? 185.750 340.113 233.710 1.00 79.59  ? 960  HIS A C     1 
ATOM   6444  O O     . HIS A 1 960  ? 185.641 341.341 233.614 1.00 79.59  ? 960  HIS A O     1 
ATOM   6445  C CB    . HIS A 1 960  ? 185.182 338.667 231.739 1.00 79.59  ? 960  HIS A CB    1 
ATOM   6446  C CG    . HIS A 1 960  ? 184.532 339.614 230.780 1.00 79.59  ? 960  HIS A CG    1 
ATOM   6447  N ND1   . HIS A 1 960  ? 183.305 339.362 230.204 1.00 79.59  ? 960  HIS A ND1   1 
ATOM   6448  C CD2   . HIS A 1 960  ? 184.939 340.809 230.291 1.00 79.59  ? 960  HIS A CD2   1 
ATOM   6449  C CE1   . HIS A 1 960  ? 182.983 340.362 229.404 1.00 79.59  ? 960  HIS A CE1   1 
ATOM   6450  N NE2   . HIS A 1 960  ? 183.958 341.253 229.438 1.00 79.59  ? 960  HIS A NE2   1 
ATOM   6451  N N     . ILE A 1 961  ? 185.381 339.449 234.808 1.00 78.91  ? 961  ILE A N     1 
ATOM   6452  C CA    . ILE A 1 961  ? 184.814 340.154 235.954 1.00 78.91  ? 961  ILE A CA    1 
ATOM   6453  C C     . ILE A 1 961  ? 185.856 341.058 236.597 1.00 78.91  ? 961  ILE A C     1 
ATOM   6454  O O     . ILE A 1 961  ? 185.576 342.218 236.926 1.00 78.91  ? 961  ILE A O     1 
ATOM   6455  C CB    . ILE A 1 961  ? 184.238 339.146 236.967 1.00 78.91  ? 961  ILE A CB    1 
ATOM   6456  C CG1   . ILE A 1 961  ? 182.955 338.525 236.418 1.00 78.91  ? 961  ILE A CG1   1 
ATOM   6457  C CG2   . ILE A 1 961  ? 183.988 339.814 238.313 1.00 78.91  ? 961  ILE A CG2   1 
ATOM   6458  C CD1   . ILE A 1 961  ? 181.767 339.446 236.484 1.00 78.91  ? 961  ILE A CD1   1 
ATOM   6459  N N     . LEU A 1 962  ? 187.070 340.550 236.778 1.00 79.86  ? 962  LEU A N     1 
ATOM   6460  C CA    . LEU A 1 962  ? 188.139 341.319 237.397 1.00 79.86  ? 962  LEU A CA    1 
ATOM   6461  C C     . LEU A 1 962  ? 188.561 342.482 236.509 1.00 79.86  ? 962  LEU A C     1 
ATOM   6462  O O     . LEU A 1 962  ? 189.025 343.513 236.998 1.00 79.86  ? 962  LEU A O     1 
ATOM   6463  C CB    . LEU A 1 962  ? 189.336 340.418 237.689 1.00 79.86  ? 962  LEU A CB    1 
ATOM   6464  C CG    . LEU A 1 962  ? 189.262 339.528 238.929 1.00 79.86  ? 962  LEU A CG    1 
ATOM   6465  C CD1   . LEU A 1 962  ? 190.312 338.434 238.842 1.00 79.86  ? 962  LEU A CD1   1 
ATOM   6466  C CD2   . LEU A 1 962  ? 189.437 340.351 240.195 1.00 79.86  ? 962  LEU A CD2   1 
HETATM 6467  N N     . SEP A 1 963  ? 188.399 342.310 235.201 1.00 90.46  ? 963  SEP A N     1 
HETATM 6468  C CA    . SEP A 1 963  ? 188.714 343.365 234.249 1.00 90.46  ? 963  SEP A CA    1 
HETATM 6469  C CB    . SEP A 1 963  ? 188.776 342.803 232.830 1.00 90.46  ? 963  SEP A CB    1 
HETATM 6470  O OG    . SEP A 1 963  ? 189.781 343.445 232.067 1.00 90.46  ? 963  SEP A OG    1 
HETATM 6471  C C     . SEP A 1 963  ? 187.682 344.483 234.325 1.00 90.46  ? 963  SEP A C     1 
HETATM 6472  O O     . SEP A 1 963  ? 187.970 345.633 233.991 1.00 90.46  ? 963  SEP A O     1 
HETATM 6473  P P     . SEP A 1 963  ? 190.809 342.319 231.555 1.00 90.46  ? 963  SEP A P     1 
HETATM 6474  O O1P   . SEP A 1 963  ? 192.233 342.987 231.212 1.00 90.46  ? 963  SEP A O1P   1 
HETATM 6475  O O2P   . SEP A 1 963  ? 190.988 341.231 232.727 1.00 90.46  ? 963  SEP A O2P   1 
HETATM 6476  O O3P   . SEP A 1 963  ? 190.211 341.600 230.245 1.00 90.46  ? 963  SEP A O3P   1 
ATOM   6477  N N     . GLY A 1 964  ? 186.479 344.136 234.771 1.00 90.13  ? 964  GLY A N     1 
ATOM   6478  C CA    . GLY A 1 964  ? 185.387 345.088 234.840 1.00 90.13  ? 964  GLY A CA    1 
ATOM   6479  C C     . GLY A 1 964  ? 184.911 345.499 233.462 1.00 90.13  ? 964  GLY A C     1 
ATOM   6480  O O     . GLY A 1 964  ? 184.662 346.676 233.202 1.00 90.13  ? 964  GLY A O     1 
ATOM   6481  N N     . LYS A 1 965  ? 184.784 344.517 232.574 1.00 96.02  ? 965  LYS A N     1 
ATOM   6482  C CA    . LYS A 1 965  ? 184.395 344.751 231.194 1.00 96.02  ? 965  LYS A CA    1 
ATOM   6483  C C     . LYS A 1 965  ? 183.159 343.926 230.865 1.00 96.02  ? 965  LYS A C     1 
ATOM   6484  O O     . LYS A 1 965  ? 182.880 342.905 231.499 1.00 96.02  ? 965  LYS A O     1 
ATOM   6485  C CB    . LYS A 1 965  ? 185.533 344.404 230.223 1.00 96.02  ? 965  LYS A CB    1 
ATOM   6486  C CG    . LYS A 1 965  ? 186.521 345.534 229.995 1.00 96.02  ? 965  LYS A CG    1 
ATOM   6487  C CD    . LYS A 1 965  ? 185.819 346.788 229.505 1.00 96.02  ? 965  LYS A CD    1 
ATOM   6488  C CE    . LYS A 1 965  ? 186.812 347.806 228.973 1.00 96.02  ? 965  LYS A CE    1 
ATOM   6489  N NZ    . LYS A 1 965  ? 186.212 348.668 227.918 1.00 96.02  ? 965  LYS A NZ    1 
ATOM   6490  N N     . GLU A 1 966  ? 182.419 344.384 229.860 1.00 106.56 ? 966  GLU A N     1 
ATOM   6491  C CA    . GLU A 1 966  ? 181.222 343.682 229.413 1.00 106.56 ? 966  GLU A CA    1 
ATOM   6492  C C     . GLU A 1 966  ? 181.254 343.461 227.904 1.00 106.56 ? 966  GLU A C     1 
ATOM   6493  O O     . GLU A 1 966  ? 181.798 344.276 227.159 1.00 106.56 ? 966  GLU A O     1 
ATOM   6494  C CB    . GLU A 1 966  ? 179.964 344.459 229.806 1.00 106.56 ? 966  GLU A CB    1 
ATOM   6495  C CG    . GLU A 1 966  ? 178.674 343.870 229.257 1.00 106.56 ? 966  GLU A CG    1 
ATOM   6496  C CD    . GLU A 1 966  ? 178.556 342.380 229.517 1.00 106.56 ? 966  GLU A CD    1 
ATOM   6497  O OE1   . GLU A 1 966  ? 178.686 341.968 230.689 1.00 106.56 ? 966  GLU A OE1   1 
ATOM   6498  O OE2   . GLU A 1 966  ? 178.335 341.622 228.550 1.00 106.56 ? 966  GLU A OE2   1 
ATOM   6499  N N     . GLN A 1 1053 ? 172.689 350.561 233.581 1.00 86.73  ? 1053 GLN A N     1 
ATOM   6500  C CA    . GLN A 1 1053 ? 174.066 350.147 233.340 1.00 86.73  ? 1053 GLN A CA    1 
ATOM   6501  C C     . GLN A 1 1053 ? 174.990 350.733 234.401 1.00 86.73  ? 1053 GLN A C     1 
ATOM   6502  O O     . GLN A 1 1053 ? 175.887 350.053 234.902 1.00 86.73  ? 1053 GLN A O     1 
ATOM   6503  C CB    . GLN A 1 1053 ? 174.516 350.573 231.938 1.00 86.73  ? 1053 GLN A CB    1 
ATOM   6504  C CG    . GLN A 1 1053 ? 175.923 350.126 231.548 1.00 86.73  ? 1053 GLN A CG    1 
ATOM   6505  C CD    . GLN A 1 1053 ? 177.004 351.091 232.001 1.00 86.73  ? 1053 GLN A CD    1 
ATOM   6506  O OE1   . GLN A 1 1053 ? 177.123 352.199 231.476 1.00 86.73  ? 1053 GLN A OE1   1 
ATOM   6507  N NE2   . GLN A 1 1053 ? 177.801 350.672 232.977 1.00 86.73  ? 1053 GLN A NE2   1 
ATOM   6508  N N     . TRP A 1 1054 ? 174.768 352.006 234.736 1.00 84.39  ? 1054 TRP A N     1 
ATOM   6509  C CA    . TRP A 1 1054 ? 175.612 352.667 235.727 1.00 84.39  ? 1054 TRP A CA    1 
ATOM   6510  C C     . TRP A 1 1054 ? 175.385 352.094 237.120 1.00 84.39  ? 1054 TRP A C     1 
ATOM   6511  O O     . TRP A 1 1054 ? 176.322 352.007 237.922 1.00 84.39  ? 1054 TRP A O     1 
ATOM   6512  C CB    . TRP A 1 1054 ? 175.359 354.174 235.713 1.00 84.39  ? 1054 TRP A CB    1 
ATOM   6513  C CG    . TRP A 1 1054 ? 176.280 354.930 234.800 1.00 84.39  ? 1054 TRP A CG    1 
ATOM   6514  C CD1   . TRP A 1 1054 ? 175.922 355.709 233.738 1.00 84.39  ? 1054 TRP A CD1   1 
ATOM   6515  C CD2   . TRP A 1 1054 ? 177.711 354.984 234.872 1.00 84.39  ? 1054 TRP A CD2   1 
ATOM   6516  N NE1   . TRP A 1 1054 ? 177.040 356.241 233.143 1.00 84.39  ? 1054 TRP A NE1   1 
ATOM   6517  C CE2   . TRP A 1 1054 ? 178.151 355.812 233.820 1.00 84.39  ? 1054 TRP A CE2   1 
ATOM   6518  C CE3   . TRP A 1 1054 ? 178.663 354.412 235.722 1.00 84.39  ? 1054 TRP A CE3   1 
ATOM   6519  C CZ2   . TRP A 1 1054 ? 179.499 356.081 233.595 1.00 84.39  ? 1054 TRP A CZ2   1 
ATOM   6520  C CZ3   . TRP A 1 1054 ? 180.001 354.680 235.497 1.00 84.39  ? 1054 TRP A CZ3   1 
ATOM   6521  C CH2   . TRP A 1 1054 ? 180.406 355.508 234.443 1.00 84.39  ? 1054 TRP A CH2   1 
ATOM   6522  N N     . GLN A 1 1055 ? 174.144 351.711 237.433 1.00 91.43  ? 1055 GLN A N     1 
ATOM   6523  C CA    . GLN A 1 1055 ? 173.865 351.105 238.732 1.00 91.43  ? 1055 GLN A CA    1 
ATOM   6524  C C     . GLN A 1 1055 ? 174.609 349.785 238.896 1.00 91.43  ? 1055 GLN A C     1 
ATOM   6525  O O     . GLN A 1 1055 ? 175.202 349.523 239.950 1.00 91.43  ? 1055 GLN A O     1 
ATOM   6526  C CB    . GLN A 1 1055 ? 172.361 350.898 238.902 1.00 91.43  ? 1055 GLN A CB    1 
ATOM   6527  C CG    . GLN A 1 1055 ? 171.949 350.441 240.291 1.00 91.43  ? 1055 GLN A CG    1 
ATOM   6528  C CD    . GLN A 1 1055 ? 170.444 350.407 240.469 1.00 91.43  ? 1055 GLN A CD    1 
ATOM   6529  O OE1   . GLN A 1 1055 ? 169.693 350.811 239.582 1.00 91.43  ? 1055 GLN A OE1   1 
ATOM   6530  N NE2   . GLN A 1 1055 ? 169.995 349.923 241.622 1.00 91.43  ? 1055 GLN A NE2   1 
ATOM   6531  N N     . ARG A 1 1056 ? 174.593 348.944 237.859 1.00 99.36  ? 1056 ARG A N     1 
ATOM   6532  C CA    . ARG A 1 1056 ? 175.328 347.685 237.915 1.00 99.36  ? 1056 ARG A CA    1 
ATOM   6533  C C     . ARG A 1 1056 ? 176.827 347.929 238.030 1.00 99.36  ? 1056 ARG A C     1 
ATOM   6534  O O     . ARG A 1 1056 ? 177.526 347.216 238.759 1.00 99.36  ? 1056 ARG A O     1 
ATOM   6535  C CB    . ARG A 1 1056 ? 175.012 346.840 236.681 1.00 99.36  ? 1056 ARG A CB    1 
ATOM   6536  C CG    . ARG A 1 1056 ? 175.660 345.465 236.683 1.00 99.36  ? 1056 ARG A CG    1 
ATOM   6537  C CD    . ARG A 1 1056 ? 175.263 344.668 235.450 1.00 99.36  ? 1056 ARG A CD    1 
ATOM   6538  N NE    . ARG A 1 1056 ? 176.313 343.747 235.031 1.00 99.36  ? 1056 ARG A NE    1 
ATOM   6539  C CZ    . ARG A 1 1056 ? 177.406 344.105 234.370 1.00 99.36  ? 1056 ARG A CZ    1 
ATOM   6540  N NH1   . ARG A 1 1056 ? 177.627 345.364 234.028 1.00 99.36  ? 1056 ARG A NH1   1 
ATOM   6541  N NH2   . ARG A 1 1056 ? 178.300 343.176 234.043 1.00 99.36  ? 1056 ARG A NH2   1 
ATOM   6542  N N     . ARG A 1 1057 ? 177.338 348.932 237.313 1.00 83.90  ? 1057 ARG A N     1 
ATOM   6543  C CA    . ARG A 1 1057 ? 178.759 349.258 237.392 1.00 83.90  ? 1057 ARG A CA    1 
ATOM   6544  C C     . ARG A 1 1057 ? 179.143 349.701 238.799 1.00 83.90  ? 1057 ARG A C     1 
ATOM   6545  O O     . ARG A 1 1057 ? 180.184 349.294 239.331 1.00 83.90  ? 1057 ARG A O     1 
ATOM   6546  C CB    . ARG A 1 1057 ? 179.097 350.342 236.370 1.00 83.90  ? 1057 ARG A CB    1 
ATOM   6547  N N     . ARG A 1 1058 ? 178.310 350.541 239.418 1.00 79.42  ? 1058 ARG A N     1 
ATOM   6548  C CA    . ARG A 1 1058 ? 178.576 350.977 240.784 1.00 79.42  ? 1058 ARG A CA    1 
ATOM   6549  C C     . ARG A 1 1058 ? 178.509 349.809 241.758 1.00 79.42  ? 1058 ARG A C     1 
ATOM   6550  O O     . ARG A 1 1058 ? 179.309 349.729 242.698 1.00 79.42  ? 1058 ARG A O     1 
ATOM   6551  C CB    . ARG A 1 1058 ? 177.590 352.073 241.190 1.00 79.42  ? 1058 ARG A CB    1 
ATOM   6552  C CG    . ARG A 1 1058 ? 177.804 353.398 240.477 1.00 79.42  ? 1058 ARG A CG    1 
ATOM   6553  C CD    . ARG A 1 1058 ? 178.172 354.499 241.461 1.00 79.42  ? 1058 ARG A CD    1 
ATOM   6554  N NE    . ARG A 1 1058 ? 178.717 355.676 240.795 1.00 79.42  ? 1058 ARG A NE    1 
ATOM   6555  C CZ    . ARG A 1 1058 ? 177.997 356.553 240.108 1.00 79.42  ? 1058 ARG A CZ    1 
ATOM   6556  N NH1   . ARG A 1 1058 ? 176.686 356.425 239.982 1.00 79.42  ? 1058 ARG A NH1   1 
ATOM   6557  N NH2   . ARG A 1 1058 ? 178.608 357.587 239.536 1.00 79.42  ? 1058 ARG A NH2   1 
ATOM   6558  N N     . ARG A 1 1059 ? 177.555 348.896 241.555 1.00 87.39  ? 1059 ARG A N     1 
ATOM   6559  C CA    . ARG A 1 1059 ? 177.467 347.721 242.416 1.00 87.39  ? 1059 ARG A CA    1 
ATOM   6560  C C     . ARG A 1 1059 ? 178.713 346.853 242.288 1.00 87.39  ? 1059 ARG A C     1 
ATOM   6561  O O     . ARG A 1 1059 ? 179.240 346.358 243.292 1.00 87.39  ? 1059 ARG A O     1 
ATOM   6562  C CB    . ARG A 1 1059 ? 176.210 346.918 242.082 1.00 87.39  ? 1059 ARG A CB    1 
ATOM   6563  C CG    . ARG A 1 1059 ? 175.558 346.260 243.289 1.00 87.39  ? 1059 ARG A CG    1 
ATOM   6564  C CD    . ARG A 1 1059 ? 174.633 345.121 242.886 1.00 87.39  ? 1059 ARG A CD    1 
ATOM   6565  N NE    . ARG A 1 1059 ? 175.191 344.295 241.822 1.00 87.39  ? 1059 ARG A NE    1 
ATOM   6566  C CZ    . ARG A 1 1059 ? 175.923 343.209 242.024 1.00 87.39  ? 1059 ARG A CZ    1 
ATOM   6567  N NH1   . ARG A 1 1059 ? 176.217 342.791 243.245 1.00 87.39  ? 1059 ARG A NH1   1 
ATOM   6568  N NH2   . ARG A 1 1059 ? 176.369 342.522 240.977 1.00 87.39  ? 1059 ARG A NH2   1 
ATOM   6569  N N     . LEU A 1 1060 ? 179.202 346.660 241.060 1.00 83.82  ? 1060 LEU A N     1 
ATOM   6570  C CA    . LEU A 1 1060 ? 180.430 345.894 240.862 1.00 83.82  ? 1060 LEU A CA    1 
ATOM   6571  C C     . LEU A 1 1060 ? 181.622 346.578 241.521 1.00 83.82  ? 1060 LEU A C     1 
ATOM   6572  O O     . LEU A 1 1060 ? 182.455 345.916 242.152 1.00 83.82  ? 1060 LEU A O     1 
ATOM   6573  C CB    . LEU A 1 1060 ? 180.700 345.687 239.370 1.00 83.82  ? 1060 LEU A CB    1 
ATOM   6574  C CG    . LEU A 1 1060 ? 179.698 344.928 238.497 1.00 83.82  ? 1060 LEU A CG    1 
ATOM   6575  C CD1   . LEU A 1 1060 ? 180.437 344.141 237.427 1.00 83.82  ? 1060 LEU A CD1   1 
ATOM   6576  C CD2   . LEU A 1 1060 ? 178.832 343.997 239.331 1.00 83.82  ? 1060 LEU A CD2   1 
ATOM   6577  N N     . ASP A 1 1061 ? 181.725 347.901 241.376 1.00 85.03  ? 1061 ASP A N     1 
ATOM   6578  C CA    . ASP A 1 1061 ? 182.846 348.622 241.972 1.00 85.03  ? 1061 ASP A CA    1 
ATOM   6579  C C     . ASP A 1 1061 ? 182.814 348.538 243.493 1.00 85.03  ? 1061 ASP A C     1 
ATOM   6580  O O     . ASP A 1 1061 ? 183.851 348.326 244.133 1.00 85.03  ? 1061 ASP A O     1 
ATOM   6581  C CB    . ASP A 1 1061 ? 182.836 350.080 241.513 1.00 85.03  ? 1061 ASP A CB    1 
ATOM   6582  C CG    . ASP A 1 1061 ? 183.878 350.363 240.449 1.00 85.03  ? 1061 ASP A CG    1 
ATOM   6583  O OD1   . ASP A 1 1061 ? 184.163 349.457 239.638 1.00 85.03  ? 1061 ASP A OD1   1 
ATOM   6584  O OD2   . ASP A 1 1061 ? 184.413 351.492 240.423 1.00 85.03  ? 1061 ASP A OD2   1 
ATOM   6585  N N     . GLY A 1 1062 ? 181.633 348.705 244.091 1.00 83.87  ? 1062 GLY A N     1 
ATOM   6586  C CA    . GLY A 1 1062 ? 181.529 348.627 245.538 1.00 83.87  ? 1062 GLY A CA    1 
ATOM   6587  C C     . GLY A 1 1062 ? 181.758 347.227 246.077 1.00 83.87  ? 1062 GLY A C     1 
ATOM   6588  O O     . GLY A 1 1062 ? 182.357 347.054 247.142 1.00 83.87  ? 1062 GLY A O     1 
ATOM   6589  N N     . ALA A 1 1063 ? 181.275 346.210 245.357 1.00 82.25  ? 1063 ALA A N     1 
ATOM   6590  C CA    . ALA A 1 1063 ? 181.389 344.836 245.839 1.00 82.25  ? 1063 ALA A CA    1 
ATOM   6591  C C     . ALA A 1 1063 ? 182.845 344.403 245.953 1.00 82.25  ? 1063 ALA A C     1 
ATOM   6592  O O     . ALA A 1 1063 ? 183.225 343.727 246.916 1.00 82.25  ? 1063 ALA A O     1 
ATOM   6593  C CB    . ALA A 1 1063 ? 180.618 343.892 244.917 1.00 82.25  ? 1063 ALA A CB    1 
ATOM   6594  N N     . LEU A 1 1064 ? 183.674 344.781 244.983 1.00 83.97  ? 1064 LEU A N     1 
ATOM   6595  C CA    . LEU A 1 1064 ? 185.086 344.428 244.983 1.00 83.97  ? 1064 LEU A CA    1 
ATOM   6596  C C     . LEU A 1 1064 ? 185.947 345.450 245.714 1.00 83.97  ? 1064 LEU A C     1 
ATOM   6597  O O     . LEU A 1 1064 ? 187.177 345.336 245.681 1.00 83.97  ? 1064 LEU A O     1 
ATOM   6598  C CB    . LEU A 1 1064 ? 185.590 344.252 243.546 1.00 83.97  ? 1064 LEU A CB    1 
ATOM   6599  C CG    . LEU A 1 1064 ? 185.422 342.867 242.911 1.00 83.97  ? 1064 LEU A CG    1 
ATOM   6600  C CD1   . LEU A 1 1064 ? 183.955 342.525 242.681 1.00 83.97  ? 1064 LEU A CD1   1 
ATOM   6601  C CD2   . LEU A 1 1064 ? 186.208 342.771 241.611 1.00 83.97  ? 1064 LEU A CD2   1 
ATOM   6602  N N     . ASN A 1 1065 ? 185.324 346.436 246.363 1.00 83.88  ? 1065 ASN A N     1 
ATOM   6603  C CA    . ASN A 1 1065 ? 185.993 347.483 247.143 1.00 83.88  ? 1065 ASN A CA    1 
ATOM   6604  C C     . ASN A 1 1065 ? 187.214 348.043 246.409 1.00 83.88  ? 1065 ASN A C     1 
ATOM   6605  O O     . ASN A 1 1065 ? 188.346 348.011 246.894 1.00 83.88  ? 1065 ASN A O     1 
ATOM   6606  C CB    . ASN A 1 1065 ? 186.355 346.984 248.550 1.00 83.88  ? 1065 ASN A CB    1 
ATOM   6607  C CG    . ASN A 1 1065 ? 187.326 345.817 248.540 1.00 83.88  ? 1065 ASN A CG    1 
ATOM   6608  O OD1   . ASN A 1 1065 ? 186.918 344.655 248.531 1.00 83.88  ? 1065 ASN A OD1   1 
ATOM   6609  N ND2   . ASN A 1 1065 ? 188.619 346.121 248.545 1.00 83.88  ? 1065 ASN A ND2   1 
ATOM   6610  N N     . ARG A 1 1066 ? 186.954 348.575 245.217 1.00 81.26  ? 1066 ARG A N     1 
ATOM   6611  C CA    . ARG A 1 1066 ? 187.991 349.188 244.400 1.00 81.26  ? 1066 ARG A CA    1 
ATOM   6612  C C     . ARG A 1 1066 ? 188.056 350.681 244.694 1.00 81.26  ? 1066 ARG A C     1 
ATOM   6613  O O     . ARG A 1 1066 ? 187.060 351.395 244.539 1.00 81.26  ? 1066 ARG A O     1 
ATOM   6614  C CB    . ARG A 1 1066 ? 187.718 348.950 242.914 1.00 81.26  ? 1066 ARG A CB    1 
ATOM   6615  C CG    . ARG A 1 1066 ? 187.882 347.503 242.477 1.00 81.26  ? 1066 ARG A CG    1 
ATOM   6616  C CD    . ARG A 1 1066 ? 188.391 347.411 241.047 1.00 81.26  ? 1066 ARG A CD    1 
ATOM   6617  N NE    . ARG A 1 1066 ? 187.369 347.788 240.078 1.00 81.26  ? 1066 ARG A NE    1 
ATOM   6618  C CZ    . ARG A 1 1066 ? 186.466 346.956 239.579 1.00 81.26  ? 1066 ARG A CZ    1 
ATOM   6619  N NH1   . ARG A 1 1066 ? 186.426 345.683 239.936 1.00 81.26  ? 1066 ARG A NH1   1 
ATOM   6620  N NH2   . ARG A 1 1066 ? 185.579 347.412 238.699 1.00 81.26  ? 1066 ARG A NH2   1 
ATOM   6621  N N     . VAL A 1 1067 ? 189.227 351.146 245.118 1.00 82.69  ? 1067 VAL A N     1 
ATOM   6622  C CA    . VAL A 1 1067 ? 189.423 352.549 245.480 1.00 82.69  ? 1067 VAL A CA    1 
ATOM   6623  C C     . VAL A 1 1067 ? 190.689 353.064 244.817 1.00 82.69  ? 1067 VAL A C     1 
ATOM   6624  O O     . VAL A 1 1067 ? 191.598 352.290 244.485 1.00 82.69  ? 1067 VAL A O     1 
ATOM   6625  C CB    . VAL A 1 1067 ? 189.510 352.745 247.007 1.00 82.69  ? 1067 VAL A CB    1 
ATOM   6626  C CG1   . VAL A 1 1067 ? 188.149 352.524 247.651 1.00 82.69  ? 1067 VAL A CG1   1 
ATOM   6627  C CG2   . VAL A 1 1067 ? 190.547 351.807 247.604 1.00 82.69  ? 1067 VAL A CG2   1 
ATOM   6628  N N     . PRO A 1 1068 ? 190.766 354.376 244.590 1.00 83.77  ? 1068 PRO A N     1 
ATOM   6629  C CA    . PRO A 1 1068 ? 191.986 354.965 244.028 1.00 83.77  ? 1068 PRO A CA    1 
ATOM   6630  C C     . PRO A 1 1068 ? 193.219 354.627 244.855 1.00 83.77  ? 1068 PRO A C     1 
ATOM   6631  O O     . PRO A 1 1068 ? 193.140 354.286 246.038 1.00 83.77  ? 1068 PRO A O     1 
ATOM   6632  C CB    . PRO A 1 1068 ? 191.705 356.474 244.058 1.00 83.77  ? 1068 PRO A CB    1 
ATOM   6633  C CG    . PRO A 1 1068 ? 190.240 356.628 244.414 1.00 83.77  ? 1068 PRO A CG    1 
ATOM   6634  C CD    . PRO A 1 1068 ? 189.611 355.273 244.431 1.00 83.77  ? 1068 PRO A CD    1 
ATOM   6635  N N     . VAL A 1 1069 ? 194.379 354.729 244.203 1.00 89.02  ? 1069 VAL A N     1 
ATOM   6636  C CA    . VAL A 1 1069 ? 195.644 354.443 244.875 1.00 89.02  ? 1069 VAL A CA    1 
ATOM   6637  C C     . VAL A 1 1069 ? 195.897 355.447 245.993 1.00 89.02  ? 1069 VAL A C     1 
ATOM   6638  O O     . VAL A 1 1069 ? 196.339 355.081 247.089 1.00 89.02  ? 1069 VAL A O     1 
ATOM   6639  C CB    . VAL A 1 1069 ? 196.798 354.428 243.855 1.00 89.02  ? 1069 VAL A CB    1 
ATOM   6640  C CG1   . VAL A 1 1069 ? 198.112 354.084 244.540 1.00 89.02  ? 1069 VAL A CG1   1 
ATOM   6641  C CG2   . VAL A 1 1069 ? 196.501 353.446 242.732 1.00 89.02  ? 1069 VAL A CG2   1 
ATOM   6642  N N     . GLY A 1 1070 ? 195.620 356.723 245.738 1.00 95.83  ? 1070 GLY A N     1 
ATOM   6643  C CA    . GLY A 1 1070 ? 195.881 357.765 246.712 1.00 95.83  ? 1070 GLY A CA    1 
ATOM   6644  C C     . GLY A 1 1070 ? 194.731 358.013 247.667 1.00 95.83  ? 1070 GLY A C     1 
ATOM   6645  O O     . GLY A 1 1070 ? 194.683 359.051 248.333 1.00 95.83  ? 1070 GLY A O     1 
ATOM   6646  N N     . PHE A 1 1071 ? 193.793 357.064 247.736 1.00 89.52  ? 1071 PHE A N     1 
ATOM   6647  C CA    . PHE A 1 1071 ? 192.654 357.209 248.638 1.00 89.52  ? 1071 PHE A CA    1 
ATOM   6648  C C     . PHE A 1 1071 ? 193.102 357.251 250.094 1.00 89.52  ? 1071 PHE A C     1 
ATOM   6649  O O     . PHE A 1 1071 ? 192.567 358.029 250.894 1.00 89.52  ? 1071 PHE A O     1 
ATOM   6650  C CB    . PHE A 1 1071 ? 191.663 356.067 248.414 1.00 89.52  ? 1071 PHE A CB    1 
ATOM   6651  C CG    . PHE A 1 1071 ? 190.318 356.296 249.042 1.00 89.52  ? 1071 PHE A CG    1 
ATOM   6652  C CD1   . PHE A 1 1071 ? 189.530 357.367 248.654 1.00 89.52  ? 1071 PHE A CD1   1 
ATOM   6653  C CD2   . PHE A 1 1071 ? 189.840 355.439 250.020 1.00 89.52  ? 1071 PHE A CD2   1 
ATOM   6654  C CE1   . PHE A 1 1071 ? 188.292 357.580 249.229 1.00 89.52  ? 1071 PHE A CE1   1 
ATOM   6655  C CE2   . PHE A 1 1071 ? 188.602 355.646 250.599 1.00 89.52  ? 1071 PHE A CE2   1 
ATOM   6656  C CZ    . PHE A 1 1071 ? 187.827 356.718 250.203 1.00 89.52  ? 1071 PHE A CZ    1 
ATOM   6657  N N     . TYR A 1 1072 ? 194.080 356.416 250.457 1.00 96.31  ? 1072 TYR A N     1 
ATOM   6658  C CA    . TYR A 1 1072 ? 194.557 356.382 251.836 1.00 96.31  ? 1072 TYR A CA    1 
ATOM   6659  C C     . TYR A 1 1072 ? 195.156 357.721 252.248 1.00 96.31  ? 1072 TYR A C     1 
ATOM   6660  O O     . TYR A 1 1072 ? 194.880 358.222 253.345 1.00 96.31  ? 1072 TYR A O     1 
ATOM   6661  C CB    . TYR A 1 1072 ? 195.589 355.267 252.006 1.00 96.31  ? 1072 TYR A CB    1 
ATOM   6662  C CG    . TYR A 1 1072 ? 195.077 353.894 251.639 1.00 96.31  ? 1072 TYR A CG    1 
ATOM   6663  C CD1   . TYR A 1 1072 ? 193.875 353.421 252.145 1.00 96.31  ? 1072 TYR A CD1   1 
ATOM   6664  C CD2   . TYR A 1 1072 ? 195.797 353.071 250.782 1.00 96.31  ? 1072 TYR A CD2   1 
ATOM   6665  C CE1   . TYR A 1 1072 ? 193.405 352.167 251.811 1.00 96.31  ? 1072 TYR A CE1   1 
ATOM   6666  C CE2   . TYR A 1 1072 ? 195.335 351.815 250.442 1.00 96.31  ? 1072 TYR A CE2   1 
ATOM   6667  C CZ    . TYR A 1 1072 ? 194.138 351.368 250.959 1.00 96.31  ? 1072 TYR A CZ    1 
ATOM   6668  O OH    . TYR A 1 1072 ? 193.673 350.118 250.624 1.00 96.31  ? 1072 TYR A OH    1 
ATOM   6669  N N     . GLN A 1 1073 ? 195.979 358.314 251.380 1.00 95.77  ? 1073 GLN A N     1 
ATOM   6670  C CA    . GLN A 1 1073 ? 196.590 359.601 251.698 1.00 95.77  ? 1073 GLN A CA    1 
ATOM   6671  C C     . GLN A 1 1073 ? 195.538 360.696 251.821 1.00 95.77  ? 1073 GLN A C     1 
ATOM   6672  O O     . GLN A 1 1073 ? 195.625 361.553 252.708 1.00 95.77  ? 1073 GLN A O     1 
ATOM   6673  C CB    . GLN A 1 1073 ? 197.627 359.965 250.635 1.00 95.77  ? 1073 GLN A CB    1 
ATOM   6674  C CG    . GLN A 1 1073 ? 199.003 359.354 250.865 1.00 95.77  ? 1073 GLN A CG    1 
ATOM   6675  C CD    . GLN A 1 1073 ? 199.080 357.893 250.457 1.00 95.77  ? 1073 GLN A CD    1 
ATOM   6676  O OE1   . GLN A 1 1073 ? 198.065 357.260 250.163 1.00 95.77  ? 1073 GLN A OE1   1 
ATOM   6677  N NE2   . GLN A 1 1073 ? 200.291 357.350 250.436 1.00 95.77  ? 1073 GLN A NE2   1 
ATOM   6678  N N     . LYS A 1 1074 ? 194.539 360.686 250.935 1.00 99.63  ? 1074 LYS A N     1 
ATOM   6679  C CA    . LYS A 1 1074 ? 193.473 361.680 251.011 1.00 99.63  ? 1074 LYS A CA    1 
ATOM   6680  C C     . LYS A 1 1074 ? 192.683 361.546 252.307 1.00 99.63  ? 1074 LYS A C     1 
ATOM   6681  O O     . LYS A 1 1074 ? 192.371 362.549 252.961 1.00 99.63  ? 1074 LYS A O     1 
ATOM   6682  C CB    . LYS A 1 1074 ? 192.550 361.546 249.800 1.00 99.63  ? 1074 LYS A CB    1 
ATOM   6683  C CG    . LYS A 1 1074 ? 193.165 362.025 248.496 1.00 99.63  ? 1074 LYS A CG    1 
ATOM   6684  C CD    . LYS A 1 1074 ? 192.552 361.315 247.301 1.00 99.63  ? 1074 LYS A CD    1 
ATOM   6685  C CE    . LYS A 1 1074 ? 192.687 362.148 246.037 1.00 99.63  ? 1074 LYS A CE    1 
ATOM   6686  N NZ    . LYS A 1 1074 ? 192.396 361.349 244.815 1.00 99.63  ? 1074 LYS A NZ    1 
ATOM   6687  N N     . VAL A 1 1075 ? 192.357 360.311 252.697 1.00 101.77 ? 1075 VAL A N     1 
ATOM   6688  C CA    . VAL A 1 1075 ? 191.630 360.090 253.945 1.00 101.77 ? 1075 VAL A CA    1 
ATOM   6689  C C     . VAL A 1 1075 ? 192.467 360.537 255.136 1.00 101.77 ? 1075 VAL A C     1 
ATOM   6690  O O     . VAL A 1 1075 ? 191.955 361.153 256.079 1.00 101.77 ? 1075 VAL A O     1 
ATOM   6691  C CB    . VAL A 1 1075 ? 191.212 358.612 254.064 1.00 101.77 ? 1075 VAL A CB    1 
ATOM   6692  C CG1   . VAL A 1 1075 ? 190.726 358.304 255.473 1.00 101.77 ? 1075 VAL A CG1   1 
ATOM   6693  C CG2   . VAL A 1 1075 ? 190.133 358.283 253.044 1.00 101.77 ? 1075 VAL A CG2   1 
ATOM   6694  N N     . TRP A 1 1076 ? 193.767 360.233 255.114 1.00 109.93 ? 1076 TRP A N     1 
ATOM   6695  C CA    . TRP A 1 1076 ? 194.647 360.637 256.206 1.00 109.93 ? 1076 TRP A CA    1 
ATOM   6696  C C     . TRP A 1 1076 ? 194.724 362.156 256.315 1.00 109.93 ? 1076 TRP A C     1 
ATOM   6697  O O     . TRP A 1 1076 ? 194.673 362.716 257.416 1.00 109.93 ? 1076 TRP A O     1 
ATOM   6698  C CB    . TRP A 1 1076 ? 196.036 360.032 255.998 1.00 109.93 ? 1076 TRP A CB    1 
ATOM   6699  C CG    . TRP A 1 1076 ? 196.933 360.137 257.191 1.00 109.93 ? 1076 TRP A CG    1 
ATOM   6700  C CD1   . TRP A 1 1076 ? 196.703 359.625 258.434 1.00 109.93 ? 1076 TRP A CD1   1 
ATOM   6701  C CD2   . TRP A 1 1076 ? 198.216 360.772 257.248 1.00 109.93 ? 1076 TRP A CD2   1 
ATOM   6702  N NE1   . TRP A 1 1076 ? 197.757 359.914 259.267 1.00 109.93 ? 1076 TRP A NE1   1 
ATOM   6703  C CE2   . TRP A 1 1076 ? 198.700 360.616 258.562 1.00 109.93 ? 1076 TRP A CE2   1 
ATOM   6704  C CE3   . TRP A 1 1076 ? 199.000 361.462 256.319 1.00 109.93 ? 1076 TRP A CE3   1 
ATOM   6705  C CZ2   . TRP A 1 1076 ? 199.931 361.124 258.971 1.00 109.93 ? 1076 TRP A CZ2   1 
ATOM   6706  C CZ3   . TRP A 1 1076 ? 200.223 361.966 256.727 1.00 109.93 ? 1076 TRP A CZ3   1 
ATOM   6707  C CH2   . TRP A 1 1076 ? 200.676 361.795 258.041 1.00 109.93 ? 1076 TRP A CH2   1 
ATOM   6708  N N     . LYS A 1 1077 ? 194.835 362.841 255.174 1.00 104.21 ? 1077 LYS A N     1 
ATOM   6709  C CA    . LYS A 1 1077 ? 194.882 364.300 255.187 1.00 104.21 ? 1077 LYS A CA    1 
ATOM   6710  C C     . LYS A 1 1077 ? 193.573 364.888 255.701 1.00 104.21 ? 1077 LYS A C     1 
ATOM   6711  O O     . LYS A 1 1077 ? 193.579 365.860 256.467 1.00 104.21 ? 1077 LYS A O     1 
ATOM   6712  C CB    . LYS A 1 1077 ? 195.196 364.828 253.784 1.00 104.21 ? 1077 LYS A CB    1 
ATOM   6713  C CG    . LYS A 1 1077 ? 196.660 364.695 253.319 1.00 104.21 ? 1077 LYS A CG    1 
ATOM   6714  C CD    . LYS A 1 1077 ? 197.747 365.167 254.305 1.00 104.21 ? 1077 LYS A CD    1 
ATOM   6715  C CE    . LYS A 1 1077 ? 197.401 366.444 255.074 1.00 104.21 ? 1077 LYS A CE    1 
ATOM   6716  N NZ    . LYS A 1 1077 ? 198.272 366.613 256.269 1.00 104.21 ? 1077 LYS A NZ    1 
ATOM   6717  N N     . VAL A 1 1078 ? 192.440 364.312 255.290 1.00 107.95 ? 1078 VAL A N     1 
ATOM   6718  C CA    . VAL A 1 1078 ? 191.145 364.794 255.765 1.00 107.95 ? 1078 VAL A CA    1 
ATOM   6719  C C     . VAL A 1 1078 ? 191.027 364.610 257.273 1.00 107.95 ? 1078 VAL A C     1 
ATOM   6720  O O     . VAL A 1 1078 ? 190.567 365.507 257.989 1.00 107.95 ? 1078 VAL A O     1 
ATOM   6721  C CB    . VAL A 1 1078 ? 190.003 364.086 255.014 1.00 107.95 ? 1078 VAL A CB    1 
ATOM   6722  C CG1   . VAL A 1 1078 ? 188.700 364.188 255.794 1.00 107.95 ? 1078 VAL A CG1   1 
ATOM   6723  C CG2   . VAL A 1 1078 ? 189.839 364.682 253.631 1.00 107.95 ? 1078 VAL A CG2   1 
ATOM   6724  N N     . LEU A 1 1079 ? 191.446 363.448 257.778 1.00 111.34 ? 1079 LEU A N     1 
ATOM   6725  C CA    . LEU A 1 1079 ? 191.406 363.212 259.218 1.00 111.34 ? 1079 LEU A CA    1 
ATOM   6726  C C     . LEU A 1 1079 ? 192.336 364.164 259.958 1.00 111.34 ? 1079 LEU A C     1 
ATOM   6727  O O     . LEU A 1 1079 ? 192.055 364.561 261.095 1.00 111.34 ? 1079 LEU A O     1 
ATOM   6728  C CB    . LEU A 1 1079 ? 191.767 361.759 259.524 1.00 111.34 ? 1079 LEU A CB    1 
ATOM   6729  C CG    . LEU A 1 1079 ? 190.695 360.728 259.166 1.00 111.34 ? 1079 LEU A CG    1 
ATOM   6730  C CD1   . LEU A 1 1079 ? 191.288 359.328 259.107 1.00 111.34 ? 1079 LEU A CD1   1 
ATOM   6731  C CD2   . LEU A 1 1079 ? 189.545 360.792 260.159 1.00 111.34 ? 1079 LEU A CD2   1 
ATOM   6732  N N     . GLN A 1 1080 ? 193.458 364.530 259.336 1.00 111.00 ? 1080 GLN A N     1 
ATOM   6733  C CA    . GLN A 1 1080 ? 194.333 365.533 259.933 1.00 111.00 ? 1080 GLN A CA    1 
ATOM   6734  C C     . GLN A 1 1080 ? 193.655 366.897 259.988 1.00 111.00 ? 1080 GLN A C     1 
ATOM   6735  O O     . GLN A 1 1080 ? 193.795 367.630 260.974 1.00 111.00 ? 1080 GLN A O     1 
ATOM   6736  C CB    . GLN A 1 1080 ? 195.644 365.619 259.152 1.00 111.00 ? 1080 GLN A CB    1 
ATOM   6737  C CG    . GLN A 1 1080 ? 196.736 364.707 259.679 1.00 111.00 ? 1080 GLN A CG    1 
ATOM   6738  C CD    . GLN A 1 1080 ? 198.100 365.044 259.112 1.00 111.00 ? 1080 GLN A CD    1 
ATOM   6739  O OE1   . GLN A 1 1080 ? 198.700 364.247 258.393 1.00 111.00 ? 1080 GLN A OE1   1 
ATOM   6740  N NE2   . GLN A 1 1080 ? 198.597 366.233 259.434 1.00 111.00 ? 1080 GLN A NE2   1 
ATOM   6741  N N     . LYS A 1 1081 ? 192.914 367.254 258.940 1.00 110.36 ? 1081 LYS A N     1 
ATOM   6742  C CA    . LYS A 1 1081 ? 192.300 368.572 258.834 1.00 110.36 ? 1081 LYS A CA    1 
ATOM   6743  C C     . LYS A 1 1081 ? 190.889 368.634 259.409 1.00 110.36 ? 1081 LYS A C     1 
ATOM   6744  O O     . LYS A 1 1081 ? 190.273 369.704 259.374 1.00 110.36 ? 1081 LYS A O     1 
ATOM   6745  C CB    . LYS A 1 1081 ? 192.275 369.023 257.370 1.00 110.36 ? 1081 LYS A CB    1 
ATOM   6746  C CG    . LYS A 1 1081 ? 193.645 369.097 256.717 1.00 110.36 ? 1081 LYS A CG    1 
ATOM   6747  C CD    . LYS A 1 1081 ? 194.533 370.121 257.405 1.00 110.36 ? 1081 LYS A CD    1 
ATOM   6748  C CE    . LYS A 1 1081 ? 195.773 370.421 256.578 1.00 110.36 ? 1081 LYS A CE    1 
ATOM   6749  N NZ    . LYS A 1 1081 ? 195.450 371.219 255.363 1.00 110.36 ? 1081 LYS A NZ    1 
ATOM   6750  N N     . CYS A 1 1082 ? 190.362 367.529 259.933 1.00 114.91 ? 1082 CYS A N     1 
ATOM   6751  C CA    . CYS A 1 1082 ? 189.012 367.507 260.478 1.00 114.91 ? 1082 CYS A CA    1 
ATOM   6752  C C     . CYS A 1 1082 ? 189.005 366.741 261.793 1.00 114.91 ? 1082 CYS A C     1 
ATOM   6753  O O     . CYS A 1 1082 ? 189.877 365.910 262.056 1.00 114.91 ? 1082 CYS A O     1 
ATOM   6754  C CB    . CYS A 1 1082 ? 188.014 366.882 259.493 1.00 114.91 ? 1082 CYS A CB    1 
ATOM   6755  S SG    . CYS A 1 1082 ? 187.799 365.096 259.676 1.00 114.91 ? 1082 CYS A SG    1 
ATOM   6756  N N     . HIS A 1 1083 ? 188.006 367.040 262.627 1.00 114.37 ? 1083 HIS A N     1 
ATOM   6757  C CA    . HIS A 1 1083 ? 187.884 366.351 263.908 1.00 114.37 ? 1083 HIS A CA    1 
ATOM   6758  C C     . HIS A 1 1083 ? 187.543 364.878 263.718 1.00 114.37 ? 1083 HIS A C     1 
ATOM   6759  O O     . HIS A 1 1083 ? 188.026 364.020 264.466 1.00 114.37 ? 1083 HIS A O     1 
ATOM   6760  C CB    . HIS A 1 1083 ? 186.834 367.037 264.782 1.00 114.37 ? 1083 HIS A CB    1 
ATOM   6761  C CG    . HIS A 1 1083 ? 187.381 368.143 265.628 1.00 114.37 ? 1083 HIS A CG    1 
ATOM   6762  N ND1   . HIS A 1 1083 ? 186.574 369.052 266.279 1.00 114.37 ? 1083 HIS A ND1   1 
ATOM   6763  C CD2   . HIS A 1 1083 ? 188.655 368.488 265.930 1.00 114.37 ? 1083 HIS A CD2   1 
ATOM   6764  C CE1   . HIS A 1 1083 ? 187.327 369.908 266.946 1.00 114.37 ? 1083 HIS A CE1   1 
ATOM   6765  N NE2   . HIS A 1 1083 ? 188.594 369.589 266.751 1.00 114.37 ? 1083 HIS A NE2   1 
ATOM   6766  N N     . GLY A 1 1084 ? 186.705 364.566 262.737 1.00 111.36 ? 1084 GLY A N     1 
ATOM   6767  C CA    . GLY A 1 1084 ? 186.355 363.181 262.482 1.00 111.36 ? 1084 GLY A CA    1 
ATOM   6768  C C     . GLY A 1 1084 ? 185.338 363.082 261.369 1.00 111.36 ? 1084 GLY A C     1 
ATOM   6769  O O     . GLY A 1 1084 ? 184.903 364.087 260.797 1.00 111.36 ? 1084 GLY A O     1 
ATOM   6770  N N     . LEU A 1 1085 ? 184.960 361.841 261.070 1.00 112.97 ? 1085 LEU A N     1 
ATOM   6771  C CA    . LEU A 1 1085 ? 183.988 361.539 260.030 1.00 112.97 ? 1085 LEU A CA    1 
ATOM   6772  C C     . LEU A 1 1085 ? 182.886 360.662 260.606 1.00 112.97 ? 1085 LEU A C     1 
ATOM   6773  O O     . LEU A 1 1085 ? 183.156 359.743 261.385 1.00 112.97 ? 1085 LEU A O     1 
ATOM   6774  C CB    . LEU A 1 1085 ? 184.646 360.834 258.836 1.00 112.97 ? 1085 LEU A CB    1 
ATOM   6775  C CG    . LEU A 1 1085 ? 185.916 361.474 258.271 1.00 112.97 ? 1085 LEU A CG    1 
ATOM   6776  C CD1   . LEU A 1 1085 ? 186.610 360.526 257.304 1.00 112.97 ? 1085 LEU A CD1   1 
ATOM   6777  C CD2   . LEU A 1 1085 ? 185.596 362.796 257.592 1.00 112.97 ? 1085 LEU A CD2   1 
ATOM   6778  N N     . SER A 1 1086 ? 181.647 360.951 260.219 1.00 114.86 ? 1086 SER A N     1 
ATOM   6779  C CA    . SER A 1 1086 ? 180.484 360.193 260.658 1.00 114.86 ? 1086 SER A CA    1 
ATOM   6780  C C     . SER A 1 1086 ? 179.890 359.450 259.470 1.00 114.86 ? 1086 SER A C     1 
ATOM   6781  O O     . SER A 1 1086 ? 179.616 360.055 258.428 1.00 114.86 ? 1086 SER A O     1 
ATOM   6782  C CB    . SER A 1 1086 ? 179.436 361.112 261.290 1.00 114.86 ? 1086 SER A CB    1 
ATOM   6783  O OG    . SER A 1 1086 ? 178.131 360.584 261.129 1.00 114.86 ? 1086 SER A OG    1 
ATOM   6784  N N     . VAL A 1 1087 ? 179.688 358.144 259.632 1.00 115.01 ? 1087 VAL A N     1 
ATOM   6785  C CA    . VAL A 1 1087 ? 179.175 357.297 258.560 1.00 115.01 ? 1087 VAL A CA    1 
ATOM   6786  C C     . VAL A 1 1087 ? 177.838 356.716 259.007 1.00 115.01 ? 1087 VAL A C     1 
ATOM   6787  O O     . VAL A 1 1087 ? 177.498 355.575 258.674 1.00 115.01 ? 1087 VAL A O     1 
ATOM   6788  C CB    . VAL A 1 1087 ? 180.181 356.188 258.192 1.00 115.01 ? 1087 VAL A CB    1 
ATOM   6789  C CG1   . VAL A 1 1087 ? 179.903 355.641 256.794 1.00 115.01 ? 1087 VAL A CG1   1 
ATOM   6790  C CG2   . VAL A 1 1087 ? 181.609 356.706 258.294 1.00 115.01 ? 1087 VAL A CG2   1 
ATOM   6791  N N     . GLU A 1 1088 ? 177.080 357.500 259.778 1.00 117.86 ? 1088 GLU A N     1 
ATOM   6792  C CA    . GLU A 1 1088 ? 175.797 357.069 260.337 1.00 117.86 ? 1088 GLU A CA    1 
ATOM   6793  C C     . GLU A 1 1088 ? 175.990 355.814 261.191 1.00 117.86 ? 1088 GLU A C     1 
ATOM   6794  O O     . GLU A 1 1088 ? 175.524 354.721 260.866 1.00 117.86 ? 1088 GLU A O     1 
ATOM   6795  C CB    . GLU A 1 1088 ? 174.753 356.860 259.230 1.00 117.86 ? 1088 GLU A CB    1 
ATOM   6796  C CG    . GLU A 1 1088 ? 173.347 356.490 259.704 1.00 117.86 ? 1088 GLU A CG    1 
ATOM   6797  C CD    . GLU A 1 1088 ? 172.997 355.036 259.445 1.00 117.86 ? 1088 GLU A CD    1 
ATOM   6798  O OE1   . GLU A 1 1088 ? 173.300 354.538 258.341 1.00 117.86 ? 1088 GLU A OE1   1 
ATOM   6799  O OE2   . GLU A 1 1088 ? 172.418 354.393 260.346 1.00 117.86 ? 1088 GLU A OE2   1 
ATOM   6800  N N     . GLY A 1 1089 ? 176.734 355.978 262.282 1.00 112.59 ? 1089 GLY A N     1 
ATOM   6801  C CA    . GLY A 1 1089 ? 177.068 354.873 263.157 1.00 112.59 ? 1089 GLY A CA    1 
ATOM   6802  C C     . GLY A 1 1089 ? 178.525 354.898 263.566 1.00 112.59 ? 1089 GLY A C     1 
ATOM   6803  O O     . GLY A 1 1089 ? 179.409 355.027 262.713 1.00 112.59 ? 1089 GLY A O     1 
ATOM   6804  N N     . PHE A 1 1090 ? 178.782 354.780 264.871 1.00 109.10 ? 1090 PHE A N     1 
ATOM   6805  C CA    . PHE A 1 1090 ? 180.130 354.854 265.429 1.00 109.10 ? 1090 PHE A CA    1 
ATOM   6806  C C     . PHE A 1 1090 ? 180.806 356.168 265.055 1.00 109.10 ? 1090 PHE A C     1 
ATOM   6807  O O     . PHE A 1 1090 ? 180.136 357.129 264.661 1.00 109.10 ? 1090 PHE A O     1 
ATOM   6808  C CB    . PHE A 1 1090 ? 180.979 353.665 264.967 1.00 109.10 ? 1090 PHE A CB    1 
ATOM   6809  C CG    . PHE A 1 1090 ? 180.210 352.381 264.841 1.00 109.10 ? 1090 PHE A CG    1 
ATOM   6810  C CD1   . PHE A 1 1090 ? 179.756 351.716 265.968 1.00 109.10 ? 1090 PHE A CD1   1 
ATOM   6811  C CD2   . PHE A 1 1090 ? 179.946 351.836 263.595 1.00 109.10 ? 1090 PHE A CD2   1 
ATOM   6812  C CE1   . PHE A 1 1090 ? 179.048 350.534 265.855 1.00 109.10 ? 1090 PHE A CE1   1 
ATOM   6813  C CE2   . PHE A 1 1090 ? 179.239 350.654 263.475 1.00 109.10 ? 1090 PHE A CE2   1 
ATOM   6814  C CZ    . PHE A 1 1090 ? 178.790 350.002 264.606 1.00 109.10 ? 1090 PHE A CZ    1 
ATOM   6815  N N     . VAL A 1 1091 ? 182.132 356.222 265.182 1.00 110.25 ? 1091 VAL A N     1 
ATOM   6816  C CA    . VAL A 1 1091 ? 182.890 357.419 264.838 1.00 110.25 ? 1091 VAL A CA    1 
ATOM   6817  C C     . VAL A 1 1091 ? 184.341 357.012 264.634 1.00 110.25 ? 1091 VAL A C     1 
ATOM   6818  O O     . VAL A 1 1091 ? 184.817 356.039 265.226 1.00 110.25 ? 1091 VAL A O     1 
ATOM   6819  C CB    . VAL A 1 1091 ? 182.742 358.513 265.928 1.00 110.25 ? 1091 VAL A CB    1 
ATOM   6820  C CG1   . VAL A 1 1091 ? 183.549 358.156 267.170 1.00 110.25 ? 1091 VAL A CG1   1 
ATOM   6821  C CG2   . VAL A 1 1091 ? 183.151 359.875 265.383 1.00 110.25 ? 1091 VAL A CG2   1 
ATOM   6822  N N     . LEU A 1 1092 ? 185.039 357.750 263.775 1.00 112.09 ? 1092 LEU A N     1 
ATOM   6823  C CA    . LEU A 1 1092 ? 186.466 357.539 263.535 1.00 112.09 ? 1092 LEU A CA    1 
ATOM   6824  C C     . LEU A 1 1092 ? 187.207 358.775 264.028 1.00 112.09 ? 1092 LEU A C     1 
ATOM   6825  O O     . LEU A 1 1092 ? 187.139 359.842 263.391 1.00 112.09 ? 1092 LEU A O     1 
ATOM   6826  C CB    . LEU A 1 1092 ? 186.742 357.277 262.053 1.00 112.09 ? 1092 LEU A CB    1 
ATOM   6827  C CG    . LEU A 1 1092 ? 188.083 357.658 261.416 1.00 112.09 ? 1092 LEU A CG    1 
ATOM   6828  C CD1   . LEU A 1 1092 ? 189.234 356.889 262.051 1.00 112.09 ? 1092 LEU A CD1   1 
ATOM   6829  C CD2   . LEU A 1 1092 ? 188.043 357.422 259.913 1.00 112.09 ? 1092 LEU A CD2   1 
ATOM   6830  N N     . PRO A 1 1093 ? 187.890 358.698 265.167 1.00 117.91 ? 1093 PRO A N     1 
ATOM   6831  C CA    . PRO A 1 1093 ? 188.554 359.887 265.710 1.00 117.91 ? 1093 PRO A CA    1 
ATOM   6832  C C     . PRO A 1 1093 ? 189.765 360.290 264.884 1.00 117.91 ? 1093 PRO A C     1 
ATOM   6833  O O     . PRO A 1 1093 ? 190.379 359.474 264.192 1.00 117.91 ? 1093 PRO A O     1 
ATOM   6834  C CB    . PRO A 1 1093 ? 188.966 359.451 267.120 1.00 117.91 ? 1093 PRO A CB    1 
ATOM   6835  C CG    . PRO A 1 1093 ? 189.095 357.969 267.030 1.00 117.91 ? 1093 PRO A CG    1 
ATOM   6836  C CD    . PRO A 1 1093 ? 188.072 357.514 266.026 1.00 117.91 ? 1093 PRO A CD    1 
ATOM   6837  N N     . SER A 1 1094 ? 190.102 361.577 264.965 1.00 120.14 ? 1094 SER A N     1 
ATOM   6838  C CA    . SER A 1 1094 ? 191.289 362.101 264.303 1.00 120.14 ? 1094 SER A CA    1 
ATOM   6839  C C     . SER A 1 1094 ? 192.564 361.864 265.100 1.00 120.14 ? 1094 SER A C     1 
ATOM   6840  O O     . SER A 1 1094 ? 193.651 362.161 264.596 1.00 120.14 ? 1094 SER A O     1 
ATOM   6841  C CB    . SER A 1 1094 ? 191.129 363.599 264.036 1.00 120.14 ? 1094 SER A CB    1 
ATOM   6842  O OG    . SER A 1 1094 ? 192.388 364.222 263.855 1.00 120.14 ? 1094 SER A OG    1 
ATOM   6843  N N     . SER A 1 1095 ? 192.459 361.345 266.325 1.00 122.96 ? 1095 SER A N     1 
ATOM   6844  C CA    . SER A 1 1095 ? 193.643 361.097 267.138 1.00 122.96 ? 1095 SER A CA    1 
ATOM   6845  C C     . SER A 1 1095 ? 194.487 359.947 266.604 1.00 122.96 ? 1095 SER A C     1 
ATOM   6846  O O     . SER A 1 1095 ? 195.613 359.753 267.074 1.00 122.96 ? 1095 SER A O     1 
ATOM   6847  C CB    . SER A 1 1095 ? 193.237 360.816 268.585 1.00 122.96 ? 1095 SER A CB    1 
ATOM   6848  O OG    . SER A 1 1095 ? 192.357 359.708 268.662 1.00 122.96 ? 1095 SER A OG    1 
ATOM   6849  N N     . THR A 1 1096 ? 193.971 359.178 265.644 1.00 122.14 ? 1096 THR A N     1 
ATOM   6850  C CA    . THR A 1 1096 ? 194.715 358.047 265.104 1.00 122.14 ? 1096 THR A CA    1 
ATOM   6851  C C     . THR A 1 1096 ? 195.754 358.455 264.067 1.00 122.14 ? 1096 THR A C     1 
ATOM   6852  O O     . THR A 1 1096 ? 196.554 357.608 263.657 1.00 122.14 ? 1096 THR A O     1 
ATOM   6853  C CB    . THR A 1 1096 ? 193.751 357.030 264.486 1.00 122.14 ? 1096 THR A CB    1 
ATOM   6854  O OG1   . THR A 1 1096 ? 193.512 357.366 263.114 1.00 122.14 ? 1096 THR A OG1   1 
ATOM   6855  C CG2   . THR A 1 1096 ? 192.429 357.023 265.239 1.00 122.14 ? 1096 THR A CG2   1 
ATOM   6856  N N     . THR A 1 1097 ? 195.763 359.718 263.631 1.00 119.40 ? 1097 THR A N     1 
ATOM   6857  C CA    . THR A 1 1097 ? 196.715 360.128 262.602 1.00 119.40 ? 1097 THR A CA    1 
ATOM   6858  C C     . THR A 1 1097 ? 198.132 360.221 263.157 1.00 119.40 ? 1097 THR A C     1 
ATOM   6859  O O     . THR A 1 1097 ? 199.106 360.001 262.428 1.00 119.40 ? 1097 THR A O     1 
ATOM   6860  C CB    . THR A 1 1097 ? 196.290 361.461 261.979 1.00 119.40 ? 1097 THR A CB    1 
ATOM   6861  O OG1   . THR A 1 1097 ? 197.171 361.782 260.897 1.00 119.40 ? 1097 THR A OG1   1 
ATOM   6862  C CG2   . THR A 1 1097 ? 196.334 362.586 263.004 1.00 119.40 ? 1097 THR A CG2   1 
ATOM   6863  N N     . ARG A 1 1098 ? 198.270 360.556 264.442 1.00 122.17 ? 1098 ARG A N     1 
ATOM   6864  C CA    . ARG A 1 1098 ? 199.597 360.611 265.045 1.00 122.17 ? 1098 ARG A CA    1 
ATOM   6865  C C     . ARG A 1 1098 ? 200.119 359.214 265.355 1.00 122.17 ? 1098 ARG A C     1 
ATOM   6866  O O     . ARG A 1 1098 ? 201.325 358.958 265.257 1.00 122.17 ? 1098 ARG A O     1 
ATOM   6867  C CB    . ARG A 1 1098 ? 199.564 361.472 266.308 1.00 122.17 ? 1098 ARG A CB    1 
ATOM   6868  C CG    . ARG A 1 1098 ? 198.537 361.030 267.338 1.00 122.17 ? 1098 ARG A CG    1 
ATOM   6869  C CD    . ARG A 1 1098 ? 197.768 362.217 267.895 1.00 122.17 ? 1098 ARG A CD    1 
ATOM   6870  N NE    . ARG A 1 1098 ? 196.851 362.783 266.913 1.00 122.17 ? 1098 ARG A NE    1 
ATOM   6871  C CZ    . ARG A 1 1098 ? 196.201 363.927 267.069 1.00 122.17 ? 1098 ARG A CZ    1 
ATOM   6872  N NH1   . ARG A 1 1098 ? 196.343 364.660 268.161 1.00 122.17 ? 1098 ARG A NH1   1 
ATOM   6873  N NH2   . ARG A 1 1098 ? 195.387 364.347 266.104 1.00 122.17 ? 1098 ARG A NH2   1 
ATOM   6874  N N     . GLU A 1 1099 ? 199.224 358.297 265.728 1.00 125.59 ? 1099 GLU A N     1 
ATOM   6875  C CA    . GLU A 1 1099 ? 199.639 356.930 266.021 1.00 125.59 ? 1099 GLU A CA    1 
ATOM   6876  C C     . GLU A 1 1099 ? 200.017 356.184 264.748 1.00 125.59 ? 1099 GLU A C     1 
ATOM   6877  O O     . GLU A 1 1099 ? 200.839 355.260 264.781 1.00 125.59 ? 1099 GLU A O     1 
ATOM   6878  C CB    . GLU A 1 1099 ? 198.522 356.198 266.768 1.00 125.59 ? 1099 GLU A CB    1 
ATOM   6879  C CG    . GLU A 1 1099 ? 198.996 355.167 267.784 1.00 125.59 ? 1099 GLU A CG    1 
ATOM   6880  C CD    . GLU A 1 1099 ? 199.495 353.890 267.137 1.00 125.59 ? 1099 GLU A CD    1 
ATOM   6881  O OE1   . GLU A 1 1099 ? 198.944 353.501 266.086 1.00 125.59 ? 1099 GLU A OE1   1 
ATOM   6882  O OE2   . GLU A 1 1099 ? 200.436 353.273 267.680 1.00 125.59 ? 1099 GLU A OE2   1 
ATOM   6883  N N     . MET A 1 1100 ? 199.440 356.574 263.618 1.00 117.96 ? 1100 MET A N     1 
ATOM   6884  C CA    . MET A 1 1100 ? 199.600 355.847 262.370 1.00 117.96 ? 1100 MET A CA    1 
ATOM   6885  C C     . MET A 1 1100 ? 200.344 356.698 261.344 1.00 117.96 ? 1100 MET A C     1 
ATOM   6886  O O     . MET A 1 1100 ? 200.643 357.874 261.566 1.00 117.96 ? 1100 MET A O     1 
ATOM   6887  C CB    . MET A 1 1100 ? 198.235 355.410 261.833 1.00 117.96 ? 1100 MET A CB    1 
ATOM   6888  C CG    . MET A 1 1100 ? 197.557 354.343 262.675 1.00 117.96 ? 1100 MET A CG    1 
ATOM   6889  S SD    . MET A 1 1100 ? 198.592 352.887 262.899 1.00 117.96 ? 1100 MET A SD    1 
ATOM   6890  C CE    . MET A 1 1100 ? 199.010 352.522 261.200 1.00 117.96 ? 1100 MET A CE    1 
ATOM   6891  N N     . THR A 1 1101 ? 200.651 356.078 260.213 1.00 109.91 ? 1101 THR A N     1 
ATOM   6892  C CA    . THR A 1 1101 ? 201.288 356.714 259.071 1.00 109.91 ? 1101 THR A CA    1 
ATOM   6893  C C     . THR A 1 1101 ? 200.540 356.315 257.809 1.00 109.91 ? 1101 THR A C     1 
ATOM   6894  O O     . THR A 1 1101 ? 199.925 355.244 257.756 1.00 109.91 ? 1101 THR A O     1 
ATOM   6895  C CB    . THR A 1 1101 ? 202.766 356.308 258.954 1.00 109.91 ? 1101 THR A CB    1 
ATOM   6896  O OG1   . THR A 1 1101 ? 202.869 354.882 258.867 1.00 109.91 ? 1101 THR A OG1   1 
ATOM   6897  C CG2   . THR A 1 1101 ? 203.557 356.795 260.161 1.00 109.91 ? 1101 THR A CG2   1 
ATOM   6898  N N     . PRO A 1 1102 ? 200.559 357.164 256.776 1.00 104.07 ? 1102 PRO A N     1 
ATOM   6899  C CA    . PRO A 1 1102 ? 199.839 356.815 255.538 1.00 104.07 ? 1102 PRO A CA    1 
ATOM   6900  C C     . PRO A 1 1102 ? 200.339 355.543 254.876 1.00 104.07 ? 1102 PRO A C     1 
ATOM   6901  O O     . PRO A 1 1102 ? 199.543 354.822 254.262 1.00 104.07 ? 1102 PRO A O     1 
ATOM   6902  C CB    . PRO A 1 1102 ? 200.064 358.044 254.642 1.00 104.07 ? 1102 PRO A CB    1 
ATOM   6903  C CG    . PRO A 1 1102 ? 201.245 358.748 255.230 1.00 104.07 ? 1102 PRO A CG    1 
ATOM   6904  C CD    . PRO A 1 1102 ? 201.167 358.502 256.702 1.00 104.07 ? 1102 PRO A CD    1 
ATOM   6905  N N     . GLY A 1 1103 ? 201.632 355.243 254.979 1.00 106.85 ? 1103 GLY A N     1 
ATOM   6906  C CA    . GLY A 1 1103 ? 202.191 354.060 254.359 1.00 106.85 ? 1103 GLY A CA    1 
ATOM   6907  C C     . GLY A 1 1103 ? 202.059 352.776 255.144 1.00 106.85 ? 1103 GLY A C     1 
ATOM   6908  O O     . GLY A 1 1103 ? 202.498 351.726 254.668 1.00 106.85 ? 1103 GLY A O     1 
ATOM   6909  N N     . GLU A 1 1104 ? 201.466 352.823 256.335 1.00 106.92 ? 1104 GLU A N     1 
ATOM   6910  C CA    . GLU A 1 1104 ? 201.333 351.644 257.180 1.00 106.92 ? 1104 GLU A CA    1 
ATOM   6911  C C     . GLU A 1 1104 ? 199.993 350.964 256.922 1.00 106.92 ? 1104 GLU A C     1 
ATOM   6912  O O     . GLU A 1 1104 ? 198.971 351.635 256.741 1.00 106.92 ? 1104 GLU A O     1 
ATOM   6913  C CB    . GLU A 1 1104 ? 201.472 352.025 258.654 1.00 106.92 ? 1104 GLU A CB    1 
ATOM   6914  C CG    . GLU A 1 1104 ? 202.801 351.610 259.270 1.00 106.92 ? 1104 GLU A CG    1 
ATOM   6915  C CD    . GLU A 1 1104 ? 203.080 352.307 260.588 1.00 106.92 ? 1104 GLU A CD    1 
ATOM   6916  O OE1   . GLU A 1 1104 ? 202.239 352.211 261.506 1.00 106.92 ? 1104 GLU A OE1   1 
ATOM   6917  O OE2   . GLU A 1 1104 ? 204.141 352.956 260.704 1.00 106.92 ? 1104 GLU A OE2   1 
ATOM   6918  N N     . ILE A 1 1105 ? 200.007 349.629 256.904 1.00 99.53  ? 1105 ILE A N     1 
ATOM   6919  C CA    . ILE A 1 1105 ? 198.829 348.857 256.514 1.00 99.53  ? 1105 ILE A CA    1 
ATOM   6920  C C     . ILE A 1 1105 ? 197.721 348.949 257.556 1.00 99.53  ? 1105 ILE A C     1 
ATOM   6921  O O     . ILE A 1 1105 ? 196.534 348.834 257.219 1.00 99.53  ? 1105 ILE A O     1 
ATOM   6922  C CB    . ILE A 1 1105 ? 199.227 347.392 256.247 1.00 99.53  ? 1105 ILE A CB    1 
ATOM   6923  C CG1   . ILE A 1 1105 ? 200.025 346.834 257.427 1.00 99.53  ? 1105 ILE A CG1   1 
ATOM   6924  C CG2   . ILE A 1 1105 ? 200.029 347.285 254.960 1.00 99.53  ? 1105 ILE A CG2   1 
ATOM   6925  C CD1   . ILE A 1 1105 ? 199.998 345.326 257.526 1.00 99.53  ? 1105 ILE A CD1   1 
ATOM   6926  N N     . LYS A 1 1106 ? 198.080 349.132 258.830 1.00 102.96 ? 1106 LYS A N     1 
ATOM   6927  C CA    . LYS A 1 1106 ? 197.079 349.125 259.894 1.00 102.96 ? 1106 LYS A CA    1 
ATOM   6928  C C     . LYS A 1 1106 ? 196.077 350.260 259.719 1.00 102.96 ? 1106 LYS A C     1 
ATOM   6929  O O     . LYS A 1 1106 ? 194.869 350.074 259.910 1.00 102.96 ? 1106 LYS A O     1 
ATOM   6930  C CB    . LYS A 1 1106 ? 197.760 349.206 261.261 1.00 102.96 ? 1106 LYS A CB    1 
ATOM   6931  C CG    . LYS A 1 1106 ? 198.907 348.227 261.451 1.00 102.96 ? 1106 LYS A CG    1 
ATOM   6932  C CD    . LYS A 1 1106 ? 198.461 346.796 261.195 1.00 102.96 ? 1106 LYS A CD    1 
ATOM   6933  C CE    . LYS A 1 1106 ? 199.531 345.802 261.616 1.00 102.96 ? 1106 LYS A CE    1 
ATOM   6934  N NZ    . LYS A 1 1106 ? 199.551 345.608 263.092 1.00 102.96 ? 1106 LYS A NZ    1 
ATOM   6935  N N     . PHE A 1 1107 ? 196.559 351.446 259.345 1.00 105.04 ? 1107 PHE A N     1 
ATOM   6936  C CA    . PHE A 1 1107 ? 195.648 352.555 259.084 1.00 105.04 ? 1107 PHE A CA    1 
ATOM   6937  C C     . PHE A 1 1107 ? 194.721 352.235 257.918 1.00 105.04 ? 1107 PHE A C     1 
ATOM   6938  O O     . PHE A 1 1107 ? 193.524 352.543 257.964 1.00 105.04 ? 1107 PHE A O     1 
ATOM   6939  C CB    . PHE A 1 1107 ? 196.440 353.833 258.809 1.00 105.04 ? 1107 PHE A CB    1 
ATOM   6940  N N     . SER A 1 1108 ? 195.256 351.610 256.867 1.00 101.26 ? 1108 SER A N     1 
ATOM   6941  C CA    . SER A 1 1108 ? 194.440 351.277 255.704 1.00 101.26 ? 1108 SER A CA    1 
ATOM   6942  C C     . SER A 1 1108 ? 193.326 350.304 256.071 1.00 101.26 ? 1108 SER A C     1 
ATOM   6943  O O     . SER A 1 1108 ? 192.165 350.498 255.686 1.00 101.26 ? 1108 SER A O     1 
ATOM   6944  C CB    . SER A 1 1108 ? 195.321 350.699 254.597 1.00 101.26 ? 1108 SER A CB    1 
ATOM   6945  O OG    . SER A 1 1108 ? 196.306 351.633 254.189 1.00 101.26 ? 1108 SER A OG    1 
ATOM   6946  N N     . VAL A 1 1109 ? 193.656 349.250 256.824 1.00 100.26 ? 1109 VAL A N     1 
ATOM   6947  C CA    . VAL A 1 1109 ? 192.624 348.285 257.196 1.00 100.26 ? 1109 VAL A CA    1 
ATOM   6948  C C     . VAL A 1 1109 ? 191.636 348.917 258.170 1.00 100.26 ? 1109 VAL A C     1 
ATOM   6949  O O     . VAL A 1 1109 ? 190.444 348.590 258.159 1.00 100.26 ? 1109 VAL A O     1 
ATOM   6950  C CB    . VAL A 1 1109 ? 193.245 346.988 257.757 1.00 100.26 ? 1109 VAL A CB    1 
ATOM   6951  C CG1   . VAL A 1 1109 ? 194.292 347.282 258.798 1.00 100.26 ? 1109 VAL A CG1   1 
ATOM   6952  C CG2   . VAL A 1 1109 ? 192.171 346.060 258.316 1.00 100.26 ? 1109 VAL A CG2   1 
ATOM   6953  N N     . HIS A 1 1110 ? 192.101 349.847 259.010 1.00 103.26 ? 1110 HIS A N     1 
ATOM   6954  C CA    . HIS A 1 1110 ? 191.181 350.567 259.886 1.00 103.26 ? 1110 HIS A CA    1 
ATOM   6955  C C     . HIS A 1 1110 ? 190.166 351.376 259.084 1.00 103.26 ? 1110 HIS A C     1 
ATOM   6956  O O     . HIS A 1 1110 ? 188.965 351.349 259.383 1.00 103.26 ? 1110 HIS A O     1 
ATOM   6957  C CB    . HIS A 1 1110 ? 191.962 351.479 260.833 1.00 103.26 ? 1110 HIS A CB    1 
ATOM   6958  C CG    . HIS A 1 1110 ? 191.215 351.839 262.079 1.00 103.26 ? 1110 HIS A CG    1 
ATOM   6959  N ND1   . HIS A 1 1110 ? 191.454 353.001 262.780 1.00 103.26 ? 1110 HIS A ND1   1 
ATOM   6960  C CD2   . HIS A 1 1110 ? 190.232 351.191 262.748 1.00 103.26 ? 1110 HIS A CD2   1 
ATOM   6961  C CE1   . HIS A 1 1110 ? 190.652 353.053 263.828 1.00 103.26 ? 1110 HIS A CE1   1 
ATOM   6962  N NE2   . HIS A 1 1110 ? 189.900 351.967 263.832 1.00 103.26 ? 1110 HIS A NE2   1 
ATOM   6963  N N     . VAL A 1 1111 ? 190.628 352.097 258.058 1.00 101.92 ? 1111 VAL A N     1 
ATOM   6964  C CA    . VAL A 1 1111 ? 189.705 352.872 257.229 1.00 101.92 ? 1111 VAL A CA    1 
ATOM   6965  C C     . VAL A 1 1111 ? 188.753 351.952 256.475 1.00 101.92 ? 1111 VAL A C     1 
ATOM   6966  O O     . VAL A 1 1111 ? 187.559 352.249 256.342 1.00 101.92 ? 1111 VAL A O     1 
ATOM   6967  C CB    . VAL A 1 1111 ? 190.469 353.804 256.269 1.00 101.92 ? 1111 VAL A CB    1 
ATOM   6968  C CG1   . VAL A 1 1111 ? 189.504 354.778 255.616 1.00 101.92 ? 1111 VAL A CG1   1 
ATOM   6969  C CG2   . VAL A 1 1111 ? 191.524 354.588 257.019 1.00 101.92 ? 1111 VAL A CG2   1 
ATOM   6970  N N     . GLU A 1 1112 ? 189.261 350.829 255.958 1.00 105.82 ? 1112 GLU A N     1 
ATOM   6971  C CA    . GLU A 1 1112 ? 188.380 349.887 255.268 1.00 105.82 ? 1112 GLU A CA    1 
ATOM   6972  C C     . GLU A 1 1112 ? 187.315 349.327 256.205 1.00 105.82 ? 1112 GLU A C     1 
ATOM   6973  O O     . GLU A 1 1112 ? 186.144 349.219 255.825 1.00 105.82 ? 1112 GLU A O     1 
ATOM   6974  C CB    . GLU A 1 1112 ? 189.192 348.756 254.632 1.00 105.82 ? 1112 GLU A CB    1 
ATOM   6975  C CG    . GLU A 1 1112 ? 190.246 349.183 253.604 1.00 105.82 ? 1112 GLU A CG    1 
ATOM   6976  C CD    . GLU A 1 1112 ? 189.762 350.226 252.596 1.00 105.82 ? 1112 GLU A CD    1 
ATOM   6977  O OE1   . GLU A 1 1112 ? 190.623 350.901 252.000 1.00 105.82 ? 1112 GLU A OE1   1 
ATOM   6978  O OE2   . GLU A 1 1112 ? 188.541 350.335 252.345 1.00 105.82 ? 1112 GLU A OE2   1 
ATOM   6979  N N     . SER A 1 1113 ? 187.699 348.975 257.434 1.00 103.28 ? 1113 SER A N     1 
ATOM   6980  C CA    . SER A 1 1113 ? 186.730 348.462 258.398 1.00 103.28 ? 1113 SER A CA    1 
ATOM   6981  C C     . SER A 1 1113 ? 185.704 349.525 258.767 1.00 103.28 ? 1113 SER A C     1 
ATOM   6982  O O     . SER A 1 1113 ? 184.519 349.218 258.948 1.00 103.28 ? 1113 SER A O     1 
ATOM   6983  C CB    . SER A 1 1113 ? 187.451 347.956 259.647 1.00 103.28 ? 1113 SER A CB    1 
ATOM   6984  O OG    . SER A 1 1113 ? 188.344 348.933 260.152 1.00 103.28 ? 1113 SER A OG    1 
ATOM   6985  N N     . VAL A 1 1114 ? 186.143 350.779 258.898 1.00 106.63 ? 1114 VAL A N     1 
ATOM   6986  C CA    . VAL A 1 1114 ? 185.210 351.867 259.177 1.00 106.63 ? 1114 VAL A CA    1 
ATOM   6987  C C     . VAL A 1 1114 ? 184.218 352.024 258.031 1.00 106.63 ? 1114 VAL A C     1 
ATOM   6988  O O     . VAL A 1 1114 ? 183.011 352.190 258.250 1.00 106.63 ? 1114 VAL A O     1 
ATOM   6989  C CB    . VAL A 1 1114 ? 185.983 353.173 259.448 1.00 106.63 ? 1114 VAL A CB    1 
ATOM   6990  C CG1   . VAL A 1 1114 ? 185.124 354.388 259.126 1.00 106.63 ? 1114 VAL A CG1   1 
ATOM   6991  C CG2   . VAL A 1 1114 ? 186.457 353.218 260.893 1.00 106.63 ? 1114 VAL A CG2   1 
ATOM   6992  N N     . LEU A 1 1115 ? 184.706 351.960 256.792 1.00 107.88 ? 1115 LEU A N     1 
ATOM   6993  C CA    . LEU A 1 1115 ? 183.854 352.125 255.621 1.00 107.88 ? 1115 LEU A CA    1 
ATOM   6994  C C     . LEU A 1 1115 ? 183.075 350.866 255.259 1.00 107.88 ? 1115 LEU A C     1 
ATOM   6995  O O     . LEU A 1 1115 ? 182.170 350.941 254.421 1.00 107.88 ? 1115 LEU A O     1 
ATOM   6996  C CB    . LEU A 1 1115 ? 184.695 352.565 254.420 1.00 107.88 ? 1115 LEU A CB    1 
ATOM   6997  C CG    . LEU A 1 1115 ? 184.933 354.069 254.272 1.00 107.88 ? 1115 LEU A CG    1 
ATOM   6998  C CD1   . LEU A 1 1115 ? 186.141 354.340 253.387 1.00 107.88 ? 1115 LEU A CD1   1 
ATOM   6999  C CD2   . LEU A 1 1115 ? 183.694 354.758 253.721 1.00 107.88 ? 1115 LEU A CD2   1 
ATOM   7000  N N     . ASN A 1 1116 ? 183.395 349.722 255.860 1.00 107.95 ? 1116 ASN A N     1 
ATOM   7001  C CA    . ASN A 1 1116 ? 182.723 348.467 255.547 1.00 107.95 ? 1116 ASN A CA    1 
ATOM   7002  C C     . ASN A 1 1116 ? 181.459 348.244 256.366 1.00 107.95 ? 1116 ASN A C     1 
ATOM   7003  O O     . ASN A 1 1116 ? 180.799 347.215 256.187 1.00 107.95 ? 1116 ASN A O     1 
ATOM   7004  C CB    . ASN A 1 1116 ? 183.678 347.286 255.755 1.00 107.95 ? 1116 ASN A CB    1 
ATOM   7005  C CG    . ASN A 1 1116 ? 184.221 346.739 254.450 1.00 107.95 ? 1116 ASN A CG    1 
ATOM   7006  O OD1   . ASN A 1 1116 ? 183.892 347.233 253.371 1.00 107.95 ? 1116 ASN A OD1   1 
ATOM   7007  N ND2   . ASN A 1 1116 ? 185.058 345.711 254.541 1.00 107.95 ? 1116 ASN A ND2   1 
ATOM   7008  N N     . ARG A 1 1117 ? 181.112 349.171 257.262 1.00 113.67 ? 1117 ARG A N     1 
ATOM   7009  C CA    . ARG A 1 1117 ? 179.908 349.003 258.070 1.00 113.67 ? 1117 ARG A CA    1 
ATOM   7010  C C     . ARG A 1 1117 ? 178.656 348.995 257.201 1.00 113.67 ? 1117 ARG A C     1 
ATOM   7011  O O     . ARG A 1 1117 ? 177.736 348.201 257.432 1.00 113.67 ? 1117 ARG A O     1 
ATOM   7012  C CB    . ARG A 1 1117 ? 179.825 350.105 259.125 1.00 113.67 ? 1117 ARG A CB    1 
ATOM   7013  C CG    . ARG A 1 1117 ? 181.064 350.220 259.999 1.00 113.67 ? 1117 ARG A CG    1 
ATOM   7014  C CD    . ARG A 1 1117 ? 181.393 348.898 260.675 1.00 113.67 ? 1117 ARG A CD    1 
ATOM   7015  N NE    . ARG A 1 1117 ? 180.256 348.358 261.410 1.00 113.67 ? 1117 ARG A NE    1 
ATOM   7016  C CZ    . ARG A 1 1117 ? 180.197 347.128 261.902 1.00 113.67 ? 1117 ARG A CZ    1 
ATOM   7017  N NH1   . ARG A 1 1117 ? 181.199 346.277 261.755 1.00 113.67 ? 1117 ARG A NH1   1 
ATOM   7018  N NH2   . ARG A 1 1117 ? 179.106 346.743 262.558 1.00 113.67 ? 1117 ARG A NH2   1 
ATOM   7019  N N     . VAL A 1 1118 ? 178.602 349.866 256.202 1.00 107.61 ? 1118 VAL A N     1 
ATOM   7020  C CA    . VAL A 1 1118 ? 177.447 349.897 255.298 1.00 107.61 ? 1118 VAL A CA    1 
ATOM   7021  C C     . VAL A 1 1118 ? 177.504 348.685 254.373 1.00 107.61 ? 1118 VAL A C     1 
ATOM   7022  O O     . VAL A 1 1118 ? 178.519 348.483 253.683 1.00 107.61 ? 1118 VAL A O     1 
ATOM   7023  C CB    . VAL A 1 1118 ? 177.432 351.200 254.497 1.00 107.61 ? 1118 VAL A CB    1 
ATOM   7024  C CG1   . VAL A 1 1118 ? 176.131 351.327 253.720 1.00 107.61 ? 1118 VAL A CG1   1 
ATOM   7025  C CG2   . VAL A 1 1118 ? 177.626 352.392 255.423 1.00 107.61 ? 1118 VAL A CG2   1 
ATOM   7026  N N     . PRO A 1 1119 ? 176.460 347.860 254.319 1.00 111.04 ? 1119 PRO A N     1 
ATOM   7027  C CA    . PRO A 1 1119 ? 176.480 346.663 253.466 1.00 111.04 ? 1119 PRO A CA    1 
ATOM   7028  C C     . PRO A 1 1119 ? 176.022 346.883 252.031 1.00 111.04 ? 1119 PRO A C     1 
ATOM   7029  O O     . PRO A 1 1119 ? 175.788 345.896 251.327 1.00 111.04 ? 1119 PRO A O     1 
ATOM   7030  C CB    . PRO A 1 1119 ? 175.505 345.731 254.197 1.00 111.04 ? 1119 PRO A CB    1 
ATOM   7031  C CG    . PRO A 1 1119 ? 174.507 346.658 254.815 1.00 111.04 ? 1119 PRO A CG    1 
ATOM   7032  C CD    . PRO A 1 1119 ? 175.216 347.963 255.102 1.00 111.04 ? 1119 PRO A CD    1 
ATOM   7033  N N     . GLN A 1 1120 ? 175.888 348.130 251.579 1.00 107.54 ? 1120 GLN A N     1 
ATOM   7034  C CA    . GLN A 1 1120 ? 175.442 348.405 250.221 1.00 107.54 ? 1120 GLN A CA    1 
ATOM   7035  C C     . GLN A 1 1120 ? 176.630 348.842 249.378 1.00 107.54 ? 1120 GLN A C     1 
ATOM   7036  O O     . GLN A 1 1120 ? 177.201 349.911 249.641 1.00 107.54 ? 1120 GLN A O     1 
ATOM   7037  C CB    . GLN A 1 1120 ? 174.360 349.482 250.218 1.00 107.54 ? 1120 GLN A CB    1 
ATOM   7038  C CG    . GLN A 1 1120 ? 172.959 348.957 250.481 1.00 107.54 ? 1120 GLN A CG    1 
ATOM   7039  C CD    . GLN A 1 1120 ? 172.648 348.844 251.961 1.00 107.54 ? 1120 GLN A CD    1 
ATOM   7040  O OE1   . GLN A 1 1120 ? 173.206 349.573 252.781 1.00 107.54 ? 1120 GLN A OE1   1 
ATOM   7041  N NE2   . GLN A 1 1120 ? 171.752 347.928 252.310 1.00 107.54 ? 1120 GLN A NE2   1 
ATOM   7042  N N     . PRO A 1 1121 ? 177.049 348.056 248.382 1.00 95.33  ? 1121 PRO A N     1 
ATOM   7043  C CA    . PRO A 1 1121 ? 178.185 348.477 247.539 1.00 95.33  ? 1121 PRO A CA    1 
ATOM   7044  C C     . PRO A 1 1121 ? 177.975 349.820 246.858 1.00 95.33  ? 1121 PRO A C     1 
ATOM   7045  O O     . PRO A 1 1121 ? 178.919 350.615 246.756 1.00 95.33  ? 1121 PRO A O     1 
ATOM   7046  C CB    . PRO A 1 1121 ? 178.307 347.340 246.511 1.00 95.33  ? 1121 PRO A CB    1 
ATOM   7047  C CG    . PRO A 1 1121 ? 177.127 346.438 246.727 1.00 95.33  ? 1121 PRO A CG    1 
ATOM   7048  C CD    . PRO A 1 1121 ? 176.617 346.678 248.103 1.00 95.33  ? 1121 PRO A CD    1 
ATOM   7049  N N     . GLU A 1 1122 ? 176.756 350.095 246.384 1.00 96.16  ? 1122 GLU A N     1 
ATOM   7050  C CA    . GLU A 1 1122 ? 176.474 351.394 245.783 1.00 96.16  ? 1122 GLU A CA    1 
ATOM   7051  C C     . GLU A 1 1122 ? 176.621 352.512 246.806 1.00 96.16  ? 1122 GLU A C     1 
ATOM   7052  O O     . GLU A 1 1122 ? 177.194 353.569 246.510 1.00 96.16  ? 1122 GLU A O     1 
ATOM   7053  C CB    . GLU A 1 1122 ? 175.072 351.397 245.177 1.00 96.16  ? 1122 GLU A CB    1 
ATOM   7054  C CG    . GLU A 1 1122 ? 174.850 350.337 244.111 1.00 96.16  ? 1122 GLU A CG    1 
ATOM   7055  C CD    . GLU A 1 1122 ? 173.442 349.776 244.133 1.00 96.16  ? 1122 GLU A CD    1 
ATOM   7056  O OE1   . GLU A 1 1122 ? 172.489 350.565 244.305 1.00 96.16  ? 1122 GLU A OE1   1 
ATOM   7057  O OE2   . GLU A 1 1122 ? 173.288 348.546 243.979 1.00 96.16  ? 1122 GLU A OE2   1 
ATOM   7058  N N     . TYR A 1 1123 ? 176.117 352.293 248.023 1.00 96.87  ? 1123 TYR A N     1 
ATOM   7059  C CA    . TYR A 1 1123 ? 176.311 353.273 249.083 1.00 96.87  ? 1123 TYR A CA    1 
ATOM   7060  C C     . TYR A 1 1123 ? 177.782 353.415 249.446 1.00 96.87  ? 1123 TYR A C     1 
ATOM   7061  O O     . TYR A 1 1123 ? 178.232 354.518 249.767 1.00 96.87  ? 1123 TYR A O     1 
ATOM   7062  C CB    . TYR A 1 1123 ? 175.494 352.892 250.317 1.00 96.87  ? 1123 TYR A CB    1 
ATOM   7063  C CG    . TYR A 1 1123 ? 174.967 354.079 251.092 1.00 96.87  ? 1123 TYR A CG    1 
ATOM   7064  C CD1   . TYR A 1 1123 ? 173.825 354.752 250.677 1.00 96.87  ? 1123 TYR A CD1   1 
ATOM   7065  C CD2   . TYR A 1 1123 ? 175.611 354.525 252.239 1.00 96.87  ? 1123 TYR A CD2   1 
ATOM   7066  C CE1   . TYR A 1 1123 ? 173.340 355.837 251.383 1.00 96.87  ? 1123 TYR A CE1   1 
ATOM   7067  C CE2   . TYR A 1 1123 ? 175.132 355.609 252.951 1.00 96.87  ? 1123 TYR A CE2   1 
ATOM   7068  C CZ    . TYR A 1 1123 ? 173.997 356.261 252.518 1.00 96.87  ? 1123 TYR A CZ    1 
ATOM   7069  O OH    . TYR A 1 1123 ? 173.517 357.341 253.224 1.00 96.87  ? 1123 TYR A OH    1 
ATOM   7070  N N     . ARG A 1 1124 ? 178.545 352.320 249.400 1.00 92.58  ? 1124 ARG A N     1 
ATOM   7071  C CA    . ARG A 1 1124 ? 179.978 352.405 249.664 1.00 92.58  ? 1124 ARG A CA    1 
ATOM   7072  C C     . ARG A 1 1124 ? 180.675 353.277 248.626 1.00 92.58  ? 1124 ARG A C     1 
ATOM   7073  O O     . ARG A 1 1124 ? 181.526 354.107 248.964 1.00 92.58  ? 1124 ARG A O     1 
ATOM   7074  C CB    . ARG A 1 1124 ? 180.589 351.003 249.693 1.00 92.58  ? 1124 ARG A CB    1 
ATOM   7075  C CG    . ARG A 1 1124 ? 182.103 350.989 249.830 1.00 92.58  ? 1124 ARG A CG    1 
ATOM   7076  C CD    . ARG A 1 1124 ? 182.667 349.597 249.597 1.00 92.58  ? 1124 ARG A CD    1 
ATOM   7077  N NE    . ARG A 1 1124 ? 183.751 349.285 250.522 1.00 92.58  ? 1124 ARG A NE    1 
ATOM   7078  C CZ    . ARG A 1 1124 ? 185.001 349.704 250.382 1.00 92.58  ? 1124 ARG A CZ    1 
ATOM   7079  N NH1   . ARG A 1 1124 ? 185.367 350.458 249.358 1.00 92.58  ? 1124 ARG A NH1   1 
ATOM   7080  N NH2   . ARG A 1 1124 ? 185.907 349.358 251.292 1.00 92.58  ? 1124 ARG A NH2   1 
ATOM   7081  N N     . GLN A 1 1125 ? 180.318 353.105 247.351 1.00 88.68  ? 1125 GLN A N     1 
ATOM   7082  C CA    . GLN A 1 1125 ? 180.887 353.952 246.305 1.00 88.68  ? 1125 GLN A CA    1 
ATOM   7083  C C     . GLN A 1 1125 ? 180.471 355.407 246.487 1.00 88.68  ? 1125 GLN A C     1 
ATOM   7084  O O     . GLN A 1 1125 ? 181.272 356.323 246.253 1.00 88.68  ? 1125 GLN A O     1 
ATOM   7085  C CB    . GLN A 1 1125 ? 180.468 353.439 244.927 1.00 88.68  ? 1125 GLN A CB    1 
ATOM   7086  C CG    . GLN A 1 1125 ? 181.391 353.865 243.793 1.00 88.68  ? 1125 GLN A CG    1 
ATOM   7087  C CD    . GLN A 1 1125 ? 182.735 353.159 243.827 1.00 88.68  ? 1125 GLN A CD    1 
ATOM   7088  O OE1   . GLN A 1 1125 ? 182.938 352.217 244.593 1.00 88.68  ? 1125 GLN A OE1   1 
ATOM   7089  N NE2   . GLN A 1 1125 ? 183.661 353.615 242.992 1.00 88.68  ? 1125 GLN A NE2   1 
ATOM   7090  N N     . LEU A 1 1126 ? 179.219 355.638 246.891 1.00 91.09  ? 1126 LEU A N     1 
ATOM   7091  C CA    . LEU A 1 1126 ? 178.767 357.000 247.158 1.00 91.09  ? 1126 LEU A CA    1 
ATOM   7092  C C     . LEU A 1 1126 ? 179.569 357.636 248.287 1.00 91.09  ? 1126 LEU A C     1 
ATOM   7093  O O     . LEU A 1 1126 ? 179.965 358.804 248.196 1.00 91.09  ? 1126 LEU A O     1 
ATOM   7094  C CB    . LEU A 1 1126 ? 177.275 357.004 247.490 1.00 91.09  ? 1126 LEU A CB    1 
ATOM   7095  C CG    . LEU A 1 1126 ? 176.315 357.060 246.299 1.00 91.09  ? 1126 LEU A CG    1 
ATOM   7096  C CD1   . LEU A 1 1126 ? 174.897 356.731 246.739 1.00 91.09  ? 1126 LEU A CD1   1 
ATOM   7097  C CD2   . LEU A 1 1126 ? 176.370 358.424 245.628 1.00 91.09  ? 1126 LEU A CD2   1 
ATOM   7098  N N     . LEU A 1 1127 ? 179.821 356.882 249.358 1.00 93.79  ? 1127 LEU A N     1 
ATOM   7099  C CA    . LEU A 1 1127 ? 180.636 357.402 250.453 1.00 93.79  ? 1127 LEU A CA    1 
ATOM   7100  C C     . LEU A 1 1127 ? 182.065 357.667 249.997 1.00 93.79  ? 1127 LEU A C     1 
ATOM   7101  O O     . LEU A 1 1127 ? 182.684 358.651 250.415 1.00 93.79  ? 1127 LEU A O     1 
ATOM   7102  C CB    . LEU A 1 1127 ? 180.624 356.433 251.637 1.00 93.79  ? 1127 LEU A CB    1 
ATOM   7103  C CG    . LEU A 1 1127 ? 179.264 356.040 252.220 1.00 93.79  ? 1127 LEU A CG    1 
ATOM   7104  C CD1   . LEU A 1 1127 ? 179.363 354.719 252.971 1.00 93.79  ? 1127 LEU A CD1   1 
ATOM   7105  C CD2   . LEU A 1 1127 ? 178.704 357.131 253.114 1.00 93.79  ? 1127 LEU A CD2   1 
ATOM   7106  N N     . VAL A 1 1128 ? 182.607 356.797 249.141 1.00 87.05  ? 1128 VAL A N     1 
ATOM   7107  C CA    . VAL A 1 1128 ? 183.970 356.985 248.648 1.00 87.05  ? 1128 VAL A CA    1 
ATOM   7108  C C     . VAL A 1 1128 ? 184.073 358.275 247.841 1.00 87.05  ? 1128 VAL A C     1 
ATOM   7109  O O     . VAL A 1 1128 ? 184.996 359.078 248.030 1.00 87.05  ? 1128 VAL A O     1 
ATOM   7110  C CB    . VAL A 1 1128 ? 184.415 355.763 247.824 1.00 87.05  ? 1128 VAL A CB    1 
ATOM   7111  C CG1   . VAL A 1 1128 ? 185.582 356.124 246.916 1.00 87.05  ? 1128 VAL A CG1   1 
ATOM   7112  C CG2   . VAL A 1 1128 ? 184.786 354.611 248.744 1.00 87.05  ? 1128 VAL A CG2   1 
ATOM   7113  N N     . GLU A 1 1129 ? 183.119 358.502 246.933 1.00 89.47  ? 1129 GLU A N     1 
ATOM   7114  C CA    . GLU A 1 1129 ? 183.176 359.717 246.125 1.00 89.47  ? 1129 GLU A CA    1 
ATOM   7115  C C     . GLU A 1 1129 ? 182.869 360.960 246.955 1.00 89.47  ? 1129 GLU A C     1 
ATOM   7116  O O     . GLU A 1 1129 ? 183.413 362.037 246.679 1.00 89.47  ? 1129 GLU A O     1 
ATOM   7117  C CB    . GLU A 1 1129 ? 182.234 359.613 244.923 1.00 89.47  ? 1129 GLU A CB    1 
ATOM   7118  C CG    . GLU A 1 1129 ? 180.781 359.356 245.260 1.00 89.47  ? 1129 GLU A CG    1 
ATOM   7119  C CD    . GLU A 1 1129 ? 179.965 358.958 244.044 1.00 89.47  ? 1129 GLU A CD    1 
ATOM   7120  O OE1   . GLU A 1 1129 ? 179.816 359.792 243.127 1.00 89.47  ? 1129 GLU A OE1   1 
ATOM   7121  O OE2   . GLU A 1 1129 ? 179.474 357.810 244.006 1.00 89.47  ? 1129 GLU A OE2   1 
ATOM   7122  N N     . ALA A 1 1130 ? 182.021 360.835 247.981 1.00 84.70  ? 1130 ALA A N     1 
ATOM   7123  C CA    . ALA A 1 1130 ? 181.808 361.948 248.900 1.00 84.70  ? 1130 ALA A CA    1 
ATOM   7124  C C     . ALA A 1 1130 ? 183.087 362.289 249.654 1.00 84.70  ? 1130 ALA A C     1 
ATOM   7125  O O     . ALA A 1 1130 ? 183.410 363.466 249.847 1.00 84.70  ? 1130 ALA A O     1 
ATOM   7126  C CB    . ALA A 1 1130 ? 180.678 361.618 249.874 1.00 84.70  ? 1130 ALA A CB    1 
ATOM   7127  N N     . ILE A 1 1131 ? 183.830 361.269 250.087 1.00 84.49  ? 1131 ILE A N     1 
ATOM   7128  C CA    . ILE A 1 1131 ? 185.109 361.506 250.748 1.00 84.49  ? 1131 ILE A CA    1 
ATOM   7129  C C     . ILE A 1 1131 ? 186.085 362.174 249.788 1.00 84.49  ? 1131 ILE A C     1 
ATOM   7130  O O     . ILE A 1 1131 ? 186.835 363.079 250.170 1.00 84.49  ? 1131 ILE A O     1 
ATOM   7131  C CB    . ILE A 1 1131 ? 185.669 360.184 251.310 1.00 84.49  ? 1131 ILE A CB    1 
ATOM   7132  C CG1   . ILE A 1 1131 ? 185.057 359.890 252.682 1.00 84.49  ? 1131 ILE A CG1   1 
ATOM   7133  C CG2   . ILE A 1 1131 ? 187.189 360.230 251.402 1.00 84.49  ? 1131 ILE A CG2   1 
ATOM   7134  C CD1   . ILE A 1 1131 ? 185.725 358.749 253.420 1.00 84.49  ? 1131 ILE A CD1   1 
ATOM   7135  N N     . LEU A 1 1132 ? 186.084 361.744 248.524 1.00 85.15  ? 1132 LEU A N     1 
ATOM   7136  C CA    . LEU A 1 1132 ? 186.975 362.344 247.534 1.00 85.15  ? 1132 LEU A CA    1 
ATOM   7137  C C     . LEU A 1 1132 ? 186.651 363.820 247.312 1.00 85.15  ? 1132 LEU A C     1 
ATOM   7138  O O     . LEU A 1 1132 ? 187.553 364.667 247.259 1.00 85.15  ? 1132 LEU A O     1 
ATOM   7139  C CB    . LEU A 1 1132 ? 186.891 361.569 246.218 1.00 85.15  ? 1132 LEU A CB    1 
ATOM   7140  N N     . VAL A 1 1133 ? 185.364 364.149 247.175 1.00 87.56  ? 1133 VAL A N     1 
ATOM   7141  C CA    . VAL A 1 1133 ? 184.996 365.543 246.940 1.00 87.56  ? 1133 VAL A CA    1 
ATOM   7142  C C     . VAL A 1 1133 ? 185.243 366.382 248.191 1.00 87.56  ? 1133 VAL A C     1 
ATOM   7143  O O     . VAL A 1 1133 ? 185.603 367.563 248.100 1.00 87.56  ? 1133 VAL A O     1 
ATOM   7144  C CB    . VAL A 1 1133 ? 183.541 365.654 246.440 1.00 87.56  ? 1133 VAL A CB    1 
ATOM   7145  C CG1   . VAL A 1 1133 ? 182.548 365.255 247.513 1.00 87.56  ? 1133 VAL A CG1   1 
ATOM   7146  C CG2   . VAL A 1 1133 ? 183.260 367.065 245.950 1.00 87.56  ? 1133 VAL A CG2   1 
ATOM   7147  N N     . LEU A 1 1134 ? 185.074 365.790 249.377 1.00 92.35  ? 1134 LEU A N     1 
ATOM   7148  C CA    . LEU A 1 1134 ? 185.424 366.495 250.606 1.00 92.35  ? 1134 LEU A CA    1 
ATOM   7149  C C     . LEU A 1 1134 ? 186.921 366.767 250.672 1.00 92.35  ? 1134 LEU A C     1 
ATOM   7150  O O     . LEU A 1 1134 ? 187.347 367.835 251.126 1.00 92.35  ? 1134 LEU A O     1 
ATOM   7151  C CB    . LEU A 1 1134 ? 184.968 365.690 251.823 1.00 92.35  ? 1134 LEU A CB    1 
ATOM   7152  C CG    . LEU A 1 1134 ? 183.495 365.832 252.213 1.00 92.35  ? 1134 LEU A CG    1 
ATOM   7153  C CD1   . LEU A 1 1134 ? 183.055 364.665 253.084 1.00 92.35  ? 1134 LEU A CD1   1 
ATOM   7154  C CD2   . LEU A 1 1134 ? 183.251 367.156 252.921 1.00 92.35  ? 1134 LEU A CD2   1 
ATOM   7155  N N     . THR A 1 1135 ? 187.736 365.807 250.226 1.00 94.41  ? 1135 THR A N     1 
ATOM   7156  C CA    . THR A 1 1135 ? 189.177 366.024 250.159 1.00 94.41  ? 1135 THR A CA    1 
ATOM   7157  C C     . THR A 1 1135 ? 189.513 367.156 249.198 1.00 94.41  ? 1135 THR A C     1 
ATOM   7158  O O     . THR A 1 1135 ? 190.370 367.998 249.490 1.00 94.41  ? 1135 THR A O     1 
ATOM   7159  C CB    . THR A 1 1135 ? 189.885 364.740 249.725 1.00 94.41  ? 1135 THR A CB    1 
ATOM   7160  O OG1   . THR A 1 1135 ? 189.616 363.695 250.666 1.00 94.41  ? 1135 THR A OG1   1 
ATOM   7161  C CG2   . THR A 1 1135 ? 191.386 364.967 249.645 1.00 94.41  ? 1135 THR A CG2   1 
ATOM   7162  N N     . MET A 1 1136 ? 188.849 367.185 248.041 1.00 93.49  ? 1136 MET A N     1 
ATOM   7163  C CA    . MET A 1 1136 ? 189.077 368.265 247.084 1.00 93.49  ? 1136 MET A CA    1 
ATOM   7164  C C     . MET A 1 1136 ? 188.702 369.618 247.680 1.00 93.49  ? 1136 MET A C     1 
ATOM   7165  O O     . MET A 1 1136 ? 189.429 370.605 247.510 1.00 93.49  ? 1136 MET A O     1 
ATOM   7166  C CB    . MET A 1 1136 ? 188.290 368.004 245.801 1.00 93.49  ? 1136 MET A CB    1 
ATOM   7167  N N     . LEU A 1 1137 ? 187.569 369.680 248.384 1.00 99.68  ? 1137 LEU A N     1 
ATOM   7168  C CA    . LEU A 1 1137 ? 187.156 370.929 249.018 1.00 99.68  ? 1137 LEU A CA    1 
ATOM   7169  C C     . LEU A 1 1137 ? 188.145 371.357 250.096 1.00 99.68  ? 1137 LEU A C     1 
ATOM   7170  O O     . LEU A 1 1137 ? 188.464 372.546 250.220 1.00 99.68  ? 1137 LEU A O     1 
ATOM   7171  C CB    . LEU A 1 1137 ? 185.751 370.779 249.604 1.00 99.68  ? 1137 LEU A CB    1 
ATOM   7172  C CG    . LEU A 1 1137 ? 185.225 371.946 250.443 1.00 99.68  ? 1137 LEU A CG    1 
ATOM   7173  C CD1   . LEU A 1 1137 ? 183.868 372.403 249.933 1.00 99.68  ? 1137 LEU A CD1   1 
ATOM   7174  C CD2   . LEU A 1 1137 ? 185.147 371.561 251.912 1.00 99.68  ? 1137 LEU A CD2   1 
ATOM   7175  N N     . ALA A 1 1138 ? 188.639 370.402 250.888 1.00 98.47  ? 1138 ALA A N     1 
ATOM   7176  C CA    . ALA A 1 1138 ? 189.621 370.724 251.919 1.00 98.47  ? 1138 ALA A CA    1 
ATOM   7177  C C     . ALA A 1 1138 ? 190.926 371.212 251.303 1.00 98.47  ? 1138 ALA A C     1 
ATOM   7178  O O     . ALA A 1 1138 ? 191.608 372.070 251.873 1.00 98.47  ? 1138 ALA A O     1 
ATOM   7179  C CB    . ALA A 1 1138 ? 189.868 369.506 252.809 1.00 98.47  ? 1138 ALA A CB    1 
ATOM   7180  N N     . ASP A 1 1139 ? 191.302 370.658 250.149 1.00 102.55 ? 1139 ASP A N     1 
ATOM   7181  C CA    . ASP A 1 1139 ? 192.463 371.174 249.433 1.00 102.55 ? 1139 ASP A CA    1 
ATOM   7182  C C     . ASP A 1 1139 ? 192.219 372.599 248.951 1.00 102.55 ? 1139 ASP A C     1 
ATOM   7183  O O     . ASP A 1 1139 ? 193.111 373.451 249.028 1.00 102.55 ? 1139 ASP A O     1 
ATOM   7184  C CB    . ASP A 1 1139 ? 192.809 370.260 248.258 1.00 102.55 ? 1139 ASP A CB    1 
ATOM   7185  C CG    . ASP A 1 1139 ? 193.201 368.864 248.702 1.00 102.55 ? 1139 ASP A CG    1 
ATOM   7186  O OD1   . ASP A 1 1139 ? 193.566 368.695 249.884 1.00 102.55 ? 1139 ASP A OD1   1 
ATOM   7187  O OD2   . ASP A 1 1139 ? 193.143 367.936 247.868 1.00 102.55 ? 1139 ASP A OD2   1 
ATOM   7188  N N     . ILE A 1 1140 ? 191.013 372.874 248.447 1.00 108.46 ? 1140 ILE A N     1 
ATOM   7189  C CA    . ILE A 1 1140 ? 190.698 374.218 247.972 1.00 108.46 ? 1140 ILE A CA    1 
ATOM   7190  C C     . ILE A 1 1140 ? 190.582 375.192 249.140 1.00 108.46 ? 1140 ILE A C     1 
ATOM   7191  O O     . ILE A 1 1140 ? 191.125 376.303 249.096 1.00 108.46 ? 1140 ILE A O     1 
ATOM   7192  C CB    . ILE A 1 1140 ? 189.412 374.195 247.126 1.00 108.46 ? 1140 ILE A CB    1 
ATOM   7193  C CG1   . ILE A 1 1140 ? 189.651 373.446 245.813 1.00 108.46 ? 1140 ILE A CG1   1 
ATOM   7194  C CG2   . ILE A 1 1140 ? 188.920 375.609 246.855 1.00 108.46 ? 1140 ILE A CG2   1 
ATOM   7195  C CD1   . ILE A 1 1140 ? 188.387 372.905 245.181 1.00 108.46 ? 1140 ILE A CD1   1 
ATOM   7196  N N     . GLU A 1 1141 ? 189.886 374.794 250.201 1.00 116.06 ? 1141 GLU A N     1 
ATOM   7197  C CA    . GLU A 1 1141 ? 189.605 375.666 251.334 1.00 116.06 ? 1141 GLU A CA    1 
ATOM   7198  C C     . GLU A 1 1141 ? 190.625 375.433 252.441 1.00 116.06 ? 1141 GLU A C     1 
ATOM   7199  O O     . GLU A 1 1141 ? 190.696 374.336 253.003 1.00 116.06 ? 1141 GLU A O     1 
ATOM   7200  C CB    . GLU A 1 1141 ? 188.188 375.418 251.858 1.00 116.06 ? 1141 GLU A CB    1 
ATOM   7201  C CG    . GLU A 1 1141 ? 187.902 376.007 253.230 1.00 116.06 ? 1141 GLU A CG    1 
ATOM   7202  C CD    . GLU A 1 1141 ? 187.824 374.947 254.312 1.00 116.06 ? 1141 GLU A CD    1 
ATOM   7203  O OE1   . GLU A 1 1141 ? 188.069 373.761 254.004 1.00 116.06 ? 1141 GLU A OE1   1 
ATOM   7204  O OE2   . GLU A 1 1141 ? 187.507 375.296 255.468 1.00 116.06 ? 1141 GLU A OE2   1 
ATOM   7205  N N     . ILE A 1 1142 ? 191.395 376.466 252.764 1.00 118.18 ? 1142 ILE A N     1 
ATOM   7206  C CA    . ILE A 1 1142 ? 192.404 376.384 253.819 1.00 118.18 ? 1142 ILE A CA    1 
ATOM   7207  C C     . ILE A 1 1142 ? 191.752 376.938 255.086 1.00 118.18 ? 1142 ILE A C     1 
ATOM   7208  O O     . ILE A 1 1142 ? 191.360 378.105 255.173 1.00 118.18 ? 1142 ILE A O     1 
ATOM   7209  C CB    . ILE A 1 1142 ? 193.716 377.081 253.422 1.00 118.18 ? 1142 ILE A CB    1 
ATOM   7210  C CG1   . ILE A 1 1142 ? 194.918 376.330 254.007 1.00 118.18 ? 1142 ILE A CG1   1 
ATOM   7211  C CG2   . ILE A 1 1142 ? 193.766 378.574 253.767 1.00 118.18 ? 1142 ILE A CG2   1 
ATOM   7212  C CD1   . ILE A 1 1142 ? 195.082 374.928 253.468 1.00 118.18 ? 1142 ILE A CD1   1 
ATOM   7213  N N     . HIS A 1 1143 ? 191.540 376.042 256.049 1.00 117.62 ? 1143 HIS A N     1 
ATOM   7214  C CA    . HIS A 1 1143 ? 190.958 376.337 257.354 1.00 117.62 ? 1143 HIS A CA    1 
ATOM   7215  C C     . HIS A 1 1143 ? 190.930 375.033 258.140 1.00 117.62 ? 1143 HIS A C     1 
ATOM   7216  O O     . HIS A 1 1143 ? 191.347 373.980 257.648 1.00 117.62 ? 1143 HIS A O     1 
ATOM   7217  C CB    . HIS A 1 1143 ? 189.551 376.931 257.263 1.00 117.62 ? 1143 HIS A CB    1 
ATOM   7218  N N     . SER A 1 1144 ? 190.433 375.116 259.370 1.00 113.34 ? 1144 SER A N     1 
ATOM   7219  C CA    . SER A 1 1144 ? 190.173 373.947 260.198 1.00 113.34 ? 1144 SER A CA    1 
ATOM   7220  C C     . SER A 1 1144 ? 188.670 373.801 260.389 1.00 113.34 ? 1144 SER A C     1 
ATOM   7221  O O     . SER A 1 1144 ? 188.002 374.746 260.824 1.00 113.34 ? 1144 SER A O     1 
ATOM   7222  C CB    . SER A 1 1144 ? 190.875 374.063 261.553 1.00 113.34 ? 1144 SER A CB    1 
ATOM   7223  O OG    . SER A 1 1144 ? 191.245 372.787 262.046 1.00 113.34 ? 1144 SER A OG    1 
ATOM   7224  N N     . ILE A 1 1145 ? 188.142 372.621 260.056 1.00 112.29 ? 1145 ILE A N     1 
ATOM   7225  C CA    . ILE A 1 1145 ? 186.707 372.386 260.200 1.00 112.29 ? 1145 ILE A CA    1 
ATOM   7226  C C     . ILE A 1 1145 ? 186.305 372.432 261.669 1.00 112.29 ? 1145 ILE A C     1 
ATOM   7227  O O     . ILE A 1 1145 ? 185.323 373.088 262.038 1.00 112.29 ? 1145 ILE A O     1 
ATOM   7228  C CB    . ILE A 1 1145 ? 186.310 371.051 259.537 1.00 112.29 ? 1145 ILE A CB    1 
ATOM   7229  C CG1   . ILE A 1 1145 ? 185.984 371.243 258.049 1.00 112.29 ? 1145 ILE A CG1   1 
ATOM   7230  C CG2   . ILE A 1 1145 ? 185.120 370.422 260.250 1.00 112.29 ? 1145 ILE A CG2   1 
ATOM   7231  C CD1   . ILE A 1 1145 ? 187.105 371.825 257.210 1.00 112.29 ? 1145 ILE A CD1   1 
ATOM   7232  N N     . GLY A 1 1146 ? 187.062 371.756 262.528 1.00 108.79 ? 1146 GLY A N     1 
ATOM   7233  C CA    . GLY A 1 1146 ? 186.804 371.798 263.960 1.00 108.79 ? 1146 GLY A CA    1 
ATOM   7234  C C     . GLY A 1 1146 ? 185.465 371.228 264.377 1.00 108.79 ? 1146 GLY A C     1 
ATOM   7235  O O     . GLY A 1 1146 ? 184.839 371.746 265.311 1.00 108.79 ? 1146 GLY A O     1 
ATOM   7236  N N     . SER A 1 1147 ? 185.015 370.166 263.714 1.00 110.37 ? 1147 SER A N     1 
ATOM   7237  C CA    . SER A 1 1147 ? 183.753 369.519 264.050 1.00 110.37 ? 1147 SER A CA    1 
ATOM   7238  C C     . SER A 1 1147 ? 183.691 368.182 263.325 1.00 110.37 ? 1147 SER A C     1 
ATOM   7239  O O     . SER A 1 1147 ? 184.559 367.852 262.512 1.00 110.37 ? 1147 SER A O     1 
ATOM   7240  C CB    . SER A 1 1147 ? 182.549 370.392 263.683 1.00 110.37 ? 1147 SER A CB    1 
ATOM   7241  O OG    . SER A 1 1147 ? 182.740 371.025 262.429 1.00 110.37 ? 1147 SER A OG    1 
ATOM   7242  N N     . ILE A 1 1148 ? 182.648 367.415 263.632 1.00 110.70 ? 1148 ILE A N     1 
ATOM   7243  C CA    . ILE A 1 1148 ? 182.403 366.120 263.008 1.00 110.70 ? 1148 ILE A CA    1 
ATOM   7244  C C     . ILE A 1 1148 ? 181.440 366.319 261.847 1.00 110.70 ? 1148 ILE A C     1 
ATOM   7245  O O     . ILE A 1 1148 ? 180.354 366.888 262.021 1.00 110.70 ? 1148 ILE A O     1 
ATOM   7246  C CB    . ILE A 1 1148 ? 181.838 365.109 264.021 1.00 110.70 ? 1148 ILE A CB    1 
ATOM   7247  C CG1   . ILE A 1 1148 ? 182.692 365.085 265.291 1.00 110.70 ? 1148 ILE A CG1   1 
ATOM   7248  C CG2   . ILE A 1 1148 ? 181.760 363.721 263.401 1.00 110.70 ? 1148 ILE A CG2   1 
ATOM   7249  C CD1   . ILE A 1 1148 ? 184.115 364.634 265.061 1.00 110.70 ? 1148 ILE A CD1   1 
ATOM   7250  N N     . ILE A 1 1149 ? 181.833 365.854 260.665 1.00 107.49 ? 1149 ILE A N     1 
ATOM   7251  C CA    . ILE A 1 1149 ? 181.021 365.960 259.459 1.00 107.49 ? 1149 ILE A CA    1 
ATOM   7252  C C     . ILE A 1 1149 ? 180.409 364.597 259.167 1.00 107.49 ? 1149 ILE A C     1 
ATOM   7253  O O     . ILE A 1 1149 ? 181.087 363.567 259.265 1.00 107.49 ? 1149 ILE A O     1 
ATOM   7254  C CB    . ILE A 1 1149 ? 181.843 366.479 258.264 1.00 107.49 ? 1149 ILE A CB    1 
ATOM   7255  C CG1   . ILE A 1 1149 ? 183.012 365.541 257.948 1.00 107.49 ? 1149 ILE A CG1   1 
ATOM   7256  C CG2   . ILE A 1 1149 ? 182.339 367.893 258.536 1.00 107.49 ? 1149 ILE A CG2   1 
ATOM   7257  C CD1   . ILE A 1 1149 ? 184.070 366.155 257.055 1.00 107.49 ? 1149 ILE A CD1   1 
ATOM   7258  N N     . ALA A 1 1150 ? 179.119 364.590 258.838 1.00 105.57 ? 1150 ALA A N     1 
ATOM   7259  C CA    . ALA A 1 1150 ? 178.386 363.364 258.543 1.00 105.57 ? 1150 ALA A CA    1 
ATOM   7260  C C     . ALA A 1 1150 ? 178.259 363.226 257.030 1.00 105.57 ? 1150 ALA A C     1 
ATOM   7261  O O     . ALA A 1 1150 ? 177.514 363.976 256.392 1.00 105.57 ? 1150 ALA A O     1 
ATOM   7262  C CB    . ALA A 1 1150 ? 177.014 363.375 259.213 1.00 105.57 ? 1150 ALA A CB    1 
ATOM   7263  N N     . VAL A 1 1151 ? 178.990 362.266 256.460 1.00 101.95 ? 1151 VAL A N     1 
ATOM   7264  C CA    . VAL A 1 1151 ? 178.909 362.025 255.022 1.00 101.95 ? 1151 VAL A CA    1 
ATOM   7265  C C     . VAL A 1 1151 ? 177.543 361.469 254.641 1.00 101.95 ? 1151 VAL A C     1 
ATOM   7266  O O     . VAL A 1 1151 ? 177.070 361.679 253.517 1.00 101.95 ? 1151 VAL A O     1 
ATOM   7267  C CB    . VAL A 1 1151 ? 180.056 361.099 254.570 1.00 101.95 ? 1151 VAL A CB    1 
ATOM   7268  C CG1   . VAL A 1 1151 ? 181.399 361.719 254.919 1.00 101.95 ? 1151 VAL A CG1   1 
ATOM   7269  C CG2   . VAL A 1 1151 ? 179.929 359.734 255.220 1.00 101.95 ? 1151 VAL A CG2   1 
ATOM   7270  N N     . GLU A 1 1152 ? 176.889 360.749 255.558 1.00 101.59 ? 1152 GLU A N     1 
ATOM   7271  C CA    . GLU A 1 1152 ? 175.527 360.291 255.301 1.00 101.59 ? 1152 GLU A CA    1 
ATOM   7272  C C     . GLU A 1 1152 ? 174.575 361.470 255.150 1.00 101.59 ? 1152 GLU A C     1 
ATOM   7273  O O     . GLU A 1 1152 ? 173.723 361.483 254.253 1.00 101.59 ? 1152 GLU A O     1 
ATOM   7274  C CB    . GLU A 1 1152 ? 175.064 359.361 256.423 1.00 101.59 ? 1152 GLU A CB    1 
ATOM   7275  C CG    . GLU A 1 1152 ? 173.628 358.880 256.281 1.00 101.59 ? 1152 GLU A CG    1 
ATOM   7276  C CD    . GLU A 1 1152 ? 172.684 359.562 257.254 1.00 101.59 ? 1152 GLU A CD    1 
ATOM   7277  O OE1   . GLU A 1 1152 ? 172.969 360.708 257.659 1.00 101.59 ? 1152 GLU A OE1   1 
ATOM   7278  O OE2   . GLU A 1 1152 ? 171.656 358.950 257.612 1.00 101.59 ? 1152 GLU A OE2   1 
ATOM   7279  N N     . LYS A 1 1153 ? 174.710 362.478 256.014 1.00 103.51 ? 1153 LYS A N     1 
ATOM   7280  C CA    . LYS A 1 1153 ? 173.907 363.686 255.864 1.00 103.51 ? 1153 LYS A CA    1 
ATOM   7281  C C     . LYS A 1 1153 ? 174.230 364.394 254.555 1.00 103.51 ? 1153 LYS A C     1 
ATOM   7282  O O     . LYS A 1 1153 ? 173.337 364.949 253.903 1.00 103.51 ? 1153 LYS A O     1 
ATOM   7283  C CB    . LYS A 1 1153 ? 174.130 364.618 257.054 1.00 103.51 ? 1153 LYS A CB    1 
ATOM   7284  C CG    . LYS A 1 1153 ? 172.848 365.070 257.734 1.00 103.51 ? 1153 LYS A CG    1 
ATOM   7285  C CD    . LYS A 1 1153 ? 173.109 366.200 258.715 1.00 103.51 ? 1153 LYS A CD    1 
ATOM   7286  C CE    . LYS A 1 1153 ? 173.923 365.720 259.906 1.00 103.51 ? 1153 LYS A CE    1 
ATOM   7287  N NZ    . LYS A 1 1153 ? 173.239 364.618 260.638 1.00 103.51 ? 1153 LYS A NZ    1 
ATOM   7288  N N     . ILE A 1 1154 ? 175.502 364.378 254.149 1.00 99.79  ? 1154 ILE A N     1 
ATOM   7289  C CA    . ILE A 1 1154 ? 175.898 365.023 252.900 1.00 99.79  ? 1154 ILE A CA    1 
ATOM   7290  C C     . ILE A 1 1154 ? 175.227 364.344 251.711 1.00 99.79  ? 1154 ILE A C     1 
ATOM   7291  O O     . ILE A 1 1154 ? 174.666 365.007 250.829 1.00 99.79  ? 1154 ILE A O     1 
ATOM   7292  C CB    . ILE A 1 1154 ? 177.431 365.023 252.760 1.00 99.79  ? 1154 ILE A CB    1 
ATOM   7293  C CG1   . ILE A 1 1154 ? 178.055 366.027 253.731 1.00 99.79  ? 1154 ILE A CG1   1 
ATOM   7294  C CG2   . ILE A 1 1154 ? 177.840 365.340 251.329 1.00 99.79  ? 1154 ILE A CG2   1 
ATOM   7295  C CD1   . ILE A 1 1154 ? 179.517 365.766 254.023 1.00 99.79  ? 1154 ILE A CD1   1 
ATOM   7296  N N     . VAL A 1 1155 ? 175.268 363.010 251.668 1.00 96.87  ? 1155 VAL A N     1 
ATOM   7297  C CA    . VAL A 1 1155 ? 174.668 362.307 250.538 1.00 96.87  ? 1155 VAL A CA    1 
ATOM   7298  C C     . VAL A 1 1155 ? 173.149 362.429 250.576 1.00 96.87  ? 1155 VAL A C     1 
ATOM   7299  O O     . VAL A 1 1155 ? 172.494 362.476 249.528 1.00 96.87  ? 1155 VAL A O     1 
ATOM   7300  C CB    . VAL A 1 1155 ? 175.133 360.837 250.488 1.00 96.87  ? 1155 VAL A CB    1 
ATOM   7301  C CG1   . VAL A 1 1155 ? 176.645 360.765 250.319 1.00 96.87  ? 1155 VAL A CG1   1 
ATOM   7302  C CG2   . VAL A 1 1155 ? 174.690 360.070 251.718 1.00 96.87  ? 1155 VAL A CG2   1 
ATOM   7303  N N     . HIS A 1 1156 ? 172.560 362.499 251.774 1.00 103.78 ? 1156 HIS A N     1 
ATOM   7304  C CA    . HIS A 1 1156 ? 171.121 362.731 251.868 1.00 103.78 ? 1156 HIS A CA    1 
ATOM   7305  C C     . HIS A 1 1156 ? 170.745 364.106 251.325 1.00 103.78 ? 1156 HIS A C     1 
ATOM   7306  O O     . HIS A 1 1156 ? 169.741 364.251 250.618 1.00 103.78 ? 1156 HIS A O     1 
ATOM   7307  C CB    . HIS A 1 1156 ? 170.657 362.579 253.317 1.00 103.78 ? 1156 HIS A CB    1 
ATOM   7308  C CG    . HIS A 1 1156 ? 169.443 361.718 253.475 1.00 103.78 ? 1156 HIS A CG    1 
ATOM   7309  N ND1   . HIS A 1 1156 ? 168.204 362.083 252.993 1.00 103.78 ? 1156 HIS A ND1   1 
ATOM   7310  C CD2   . HIS A 1 1156 ? 169.278 360.508 254.060 1.00 103.78 ? 1156 HIS A CD2   1 
ATOM   7311  C CE1   . HIS A 1 1156 ? 167.328 361.136 253.274 1.00 103.78 ? 1156 HIS A CE1   1 
ATOM   7312  N NE2   . HIS A 1 1156 ? 167.954 360.169 253.922 1.00 103.78 ? 1156 HIS A NE2   1 
ATOM   7313  N N     . ILE A 1 1157 ? 171.543 365.128 251.644 1.00 103.13 ? 1157 ILE A N     1 
ATOM   7314  C CA    . ILE A 1 1157 ? 171.289 366.469 251.122 1.00 103.13 ? 1157 ILE A CA    1 
ATOM   7315  C C     . ILE A 1 1157 ? 171.446 366.486 249.607 1.00 103.13 ? 1157 ILE A C     1 
ATOM   7316  O O     . ILE A 1 1157 ? 170.665 367.127 248.892 1.00 103.13 ? 1157 ILE A O     1 
ATOM   7317  C CB    . ILE A 1 1157 ? 172.216 367.493 251.805 1.00 103.13 ? 1157 ILE A CB    1 
ATOM   7318  C CG1   . ILE A 1 1157 ? 171.772 367.734 253.249 1.00 103.13 ? 1157 ILE A CG1   1 
ATOM   7319  C CG2   . ILE A 1 1157 ? 172.241 368.804 251.032 1.00 103.13 ? 1157 ILE A CG2   1 
ATOM   7320  C CD1   . ILE A 1 1157 ? 172.884 368.210 254.158 1.00 103.13 ? 1157 ILE A CD1   1 
ATOM   7321  N N     . ALA A 1 1158 ? 172.461 365.786 249.093 1.00 102.71 ? 1158 ALA A N     1 
ATOM   7322  C CA    . ALA A 1 1158 ? 172.646 365.704 247.647 1.00 102.71 ? 1158 ALA A CA    1 
ATOM   7323  C C     . ALA A 1 1158 ? 171.459 365.023 246.977 1.00 102.71 ? 1158 ALA A C     1 
ATOM   7324  O O     . ALA A 1 1158 ? 170.995 365.465 245.919 1.00 102.71 ? 1158 ALA A O     1 
ATOM   7325  C CB    . ALA A 1 1158 ? 173.944 364.964 247.324 1.00 102.71 ? 1158 ALA A CB    1 
ATOM   7326  N N     . ASN A 1 1159 ? 170.956 363.942 247.578 1.00 106.30 ? 1159 ASN A N     1 
ATOM   7327  C CA    . ASN A 1 1159 ? 169.786 363.262 247.032 1.00 106.30 ? 1159 ASN A CA    1 
ATOM   7328  C C     . ASN A 1 1159 ? 168.561 364.169 247.054 1.00 106.30 ? 1159 ASN A C     1 
ATOM   7329  O O     . ASN A 1 1159 ? 167.776 364.185 246.099 1.00 106.30 ? 1159 ASN A O     1 
ATOM   7330  C CB    . ASN A 1 1159 ? 169.525 361.970 247.809 1.00 106.30 ? 1159 ASN A CB    1 
ATOM   7331  C CG    . ASN A 1 1159 ? 168.068 361.541 247.770 1.00 106.30 ? 1159 ASN A CG    1 
ATOM   7332  O OD1   . ASN A 1 1159 ? 167.246 362.010 248.559 1.00 106.30 ? 1159 ASN A OD1   1 
ATOM   7333  N ND2   . ASN A 1 1159 ? 167.743 360.643 246.848 1.00 106.30 ? 1159 ASN A ND2   1 
ATOM   7334  N N     . ASP A 1 1160 ? 168.378 364.925 248.139 1.00 111.62 ? 1160 ASP A N     1 
ATOM   7335  C CA    . ASP A 1 1160 ? 167.251 365.851 248.214 1.00 111.62 ? 1160 ASP A CA    1 
ATOM   7336  C C     . ASP A 1 1160 ? 167.354 366.931 247.143 1.00 111.62 ? 1160 ASP A C     1 
ATOM   7337  O O     . ASP A 1 1160 ? 166.353 367.287 246.508 1.00 111.62 ? 1160 ASP A O     1 
ATOM   7338  C CB    . ASP A 1 1160 ? 167.180 366.478 249.607 1.00 111.62 ? 1160 ASP A CB    1 
ATOM   7339  C CG    . ASP A 1 1160 ? 165.853 367.164 249.873 1.00 111.62 ? 1160 ASP A CG    1 
ATOM   7340  O OD1   . ASP A 1 1160 ? 165.570 368.195 249.227 1.00 111.62 ? 1160 ASP A OD1   1 
ATOM   7341  O OD2   . ASP A 1 1160 ? 165.091 366.671 250.732 1.00 111.62 ? 1160 ASP A OD2   1 
ATOM   7342  N N     . LEU A 1 1161 ? 168.560 367.466 246.929 1.00 110.26 ? 1161 LEU A N     1 
ATOM   7343  C CA    . LEU A 1 1161 ? 168.754 368.466 245.884 1.00 110.26 ? 1161 LEU A CA    1 
ATOM   7344  C C     . LEU A 1 1161 ? 168.477 367.881 244.505 1.00 110.26 ? 1161 LEU A C     1 
ATOM   7345  O O     . LEU A 1 1161 ? 167.874 368.542 243.651 1.00 110.26 ? 1161 LEU A O     1 
ATOM   7346  C CB    . LEU A 1 1161 ? 170.172 369.032 245.953 1.00 110.26 ? 1161 LEU A CB    1 
ATOM   7347  C CG    . LEU A 1 1161 ? 170.492 369.933 247.148 1.00 110.26 ? 1161 LEU A CG    1 
ATOM   7348  C CD1   . LEU A 1 1161 ? 171.973 370.280 247.176 1.00 110.26 ? 1161 LEU A CD1   1 
ATOM   7349  C CD2   . LEU A 1 1161 ? 169.643 371.194 247.114 1.00 110.26 ? 1161 LEU A CD2   1 
ATOM   7350  N N     . PHE A 1 1162 ? 168.918 366.643 244.267 1.00 106.08 ? 1162 PHE A N     1 
ATOM   7351  C CA    . PHE A 1 1162 ? 168.646 365.993 242.988 1.00 106.08 ? 1162 PHE A CA    1 
ATOM   7352  C C     . PHE A 1 1162 ? 167.151 365.790 242.779 1.00 106.08 ? 1162 PHE A C     1 
ATOM   7353  O O     . PHE A 1 1162 ? 166.637 366.001 241.674 1.00 106.08 ? 1162 PHE A O     1 
ATOM   7354  C CB    . PHE A 1 1162 ? 169.386 364.657 242.912 1.00 106.08 ? 1162 PHE A CB    1 
ATOM   7355  C CG    . PHE A 1 1162 ? 169.233 363.954 241.594 1.00 106.08 ? 1162 PHE A CG    1 
ATOM   7356  C CD1   . PHE A 1 1162 ? 169.470 364.624 240.405 1.00 106.08 ? 1162 PHE A CD1   1 
ATOM   7357  C CD2   . PHE A 1 1162 ? 168.852 362.624 241.544 1.00 106.08 ? 1162 PHE A CD2   1 
ATOM   7358  C CE1   . PHE A 1 1162 ? 169.330 363.980 239.190 1.00 106.08 ? 1162 PHE A CE1   1 
ATOM   7359  C CE2   . PHE A 1 1162 ? 168.711 361.974 240.332 1.00 106.08 ? 1162 PHE A CE2   1 
ATOM   7360  C CZ    . PHE A 1 1162 ? 168.950 362.653 239.154 1.00 106.08 ? 1162 PHE A CZ    1 
ATOM   7361  N N     . LEU A 1 1163 ? 166.436 365.378 243.829 1.00 112.85 ? 1163 LEU A N     1 
ATOM   7362  C CA    . LEU A 1 1163 ? 164.989 365.211 243.722 1.00 112.85 ? 1163 LEU A CA    1 
ATOM   7363  C C     . LEU A 1 1163 ? 164.301 366.540 243.435 1.00 112.85 ? 1163 LEU A C     1 
ATOM   7364  O O     . LEU A 1 1163 ? 163.377 366.605 242.615 1.00 112.85 ? 1163 LEU A O     1 
ATOM   7365  C CB    . LEU A 1 1163 ? 164.432 364.588 245.003 1.00 112.85 ? 1163 LEU A CB    1 
ATOM   7366  C CG    . LEU A 1 1163 ? 164.868 363.160 245.341 1.00 112.85 ? 1163 LEU A CG    1 
ATOM   7367  C CD1   . LEU A 1 1163 ? 164.421 362.783 246.746 1.00 112.85 ? 1163 LEU A CD1   1 
ATOM   7368  C CD2   . LEU A 1 1163 ? 164.333 362.168 244.321 1.00 112.85 ? 1163 LEU A CD2   1 
ATOM   7369  N N     . GLN A 1 1164 ? 164.735 367.611 244.106 1.00 115.79 ? 1164 GLN A N     1 
ATOM   7370  C CA    . GLN A 1 1164 ? 164.155 368.926 243.854 1.00 115.79 ? 1164 GLN A CA    1 
ATOM   7371  C C     . GLN A 1 1164 ? 164.412 369.377 242.421 1.00 115.79 ? 1164 GLN A C     1 
ATOM   7372  O O     . GLN A 1 1164 ? 163.517 369.923 241.763 1.00 115.79 ? 1164 GLN A O     1 
ATOM   7373  C CB    . GLN A 1 1164 ? 164.714 369.945 244.848 1.00 115.79 ? 1164 GLN A CB    1 
ATOM   7374  C CG    . GLN A 1 1164 ? 164.084 371.325 244.745 1.00 115.79 ? 1164 GLN A CG    1 
ATOM   7375  C CD    . GLN A 1 1164 ? 164.946 372.305 243.973 1.00 115.79 ? 1164 GLN A CD    1 
ATOM   7376  O OE1   . GLN A 1 1164 ? 166.147 372.419 244.216 1.00 115.79 ? 1164 GLN A OE1   1 
ATOM   7377  N NE2   . GLN A 1 1164 ? 164.335 373.019 243.034 1.00 115.79 ? 1164 GLN A NE2   1 
ATOM   7378  N N     . GLU A 1 1165 ? 165.630 369.156 241.920 1.00 113.82 ? 1165 GLU A N     1 
ATOM   7379  C CA    . GLU A 1 1165 ? 165.944 369.528 240.544 1.00 113.82 ? 1165 GLU A CA    1 
ATOM   7380  C C     . GLU A 1 1165 ? 165.115 368.724 239.551 1.00 113.82 ? 1165 GLU A C     1 
ATOM   7381  O O     . GLU A 1 1165 ? 164.639 369.266 238.546 1.00 113.82 ? 1165 GLU A O     1 
ATOM   7382  C CB    . GLU A 1 1165 ? 167.438 369.338 240.277 1.00 113.82 ? 1165 GLU A CB    1 
ATOM   7383  C CG    . GLU A 1 1165 ? 167.904 369.886 238.938 1.00 113.82 ? 1165 GLU A CG    1 
ATOM   7384  C CD    . GLU A 1 1165 ? 169.242 370.592 239.032 1.00 113.82 ? 1165 GLU A CD    1 
ATOM   7385  O OE1   . GLU A 1 1165 ? 169.362 371.538 239.838 1.00 113.82 ? 1165 GLU A OE1   1 
ATOM   7386  O OE2   . GLU A 1 1165 ? 170.175 370.201 238.298 1.00 113.82 ? 1165 GLU A OE2   1 
ATOM   7387  N N     . GLN A 1 1166 ? 164.936 367.427 239.811 1.00 117.21 ? 1166 GLN A N     1 
ATOM   7388  C CA    . GLN A 1 1166 ? 164.118 366.600 238.929 1.00 117.21 ? 1166 GLN A CA    1 
ATOM   7389  C C     . GLN A 1 1166 ? 162.665 367.056 238.934 1.00 117.21 ? 1166 GLN A C     1 
ATOM   7390  O O     . GLN A 1 1166 ? 162.014 367.092 237.883 1.00 117.21 ? 1166 GLN A O     1 
ATOM   7391  C CB    . GLN A 1 1166 ? 164.222 365.131 239.340 1.00 117.21 ? 1166 GLN A CB    1 
ATOM   7392  C CG    . GLN A 1 1166 ? 165.533 364.470 238.950 1.00 117.21 ? 1166 GLN A CG    1 
ATOM   7393  C CD    . GLN A 1 1166 ? 165.667 364.286 237.451 1.00 117.21 ? 1166 GLN A CD    1 
ATOM   7394  O OE1   . GLN A 1 1166 ? 164.671 364.194 236.734 1.00 117.21 ? 1166 GLN A OE1   1 
ATOM   7395  N NE2   . GLN A 1 1166 ? 166.904 364.232 236.969 1.00 117.21 ? 1166 GLN A NE2   1 
ATOM   7396  N N     . LYS A 1 1167 ? 162.135 367.401 240.111 1.00 118.15 ? 1167 LYS A N     1 
ATOM   7397  C CA    . LYS A 1 1167 ? 160.768 367.906 240.187 1.00 118.15 ? 1167 LYS A CA    1 
ATOM   7398  C C     . LYS A 1 1167 ? 160.627 369.227 239.441 1.00 118.15 ? 1167 LYS A C     1 
ATOM   7399  O O     . LYS A 1 1167 ? 159.624 369.457 238.754 1.00 118.15 ? 1167 LYS A O     1 
ATOM   7400  C CB    . LYS A 1 1167 ? 160.347 368.066 241.648 1.00 118.15 ? 1167 LYS A CB    1 
ATOM   7401  C CG    . LYS A 1 1167 ? 159.840 366.786 242.291 1.00 118.15 ? 1167 LYS A CG    1 
ATOM   7402  C CD    . LYS A 1 1167 ? 158.411 366.486 241.871 1.00 118.15 ? 1167 LYS A CD    1 
ATOM   7403  C CE    . LYS A 1 1167 ? 157.858 365.280 242.614 1.00 118.15 ? 1167 LYS A CE    1 
ATOM   7404  N NZ    . LYS A 1 1167 ? 157.420 365.629 243.993 1.00 118.15 ? 1167 LYS A NZ    1 
ATOM   7405  N N     . THR A 1 1168 ? 161.619 370.110 239.570 1.00 117.75 ? 1168 THR A N     1 
ATOM   7406  C CA    . THR A 1 1168 ? 161.576 371.385 238.860 1.00 117.75 ? 1168 THR A CA    1 
ATOM   7407  C C     . THR A 1 1168 ? 161.636 371.181 237.350 1.00 117.75 ? 1168 THR A C     1 
ATOM   7408  O O     . THR A 1 1168 ? 160.937 371.868 236.595 1.00 117.75 ? 1168 THR A O     1 
ATOM   7409  C CB    . THR A 1 1168 ? 162.722 372.284 239.326 1.00 117.75 ? 1168 THR A CB    1 
ATOM   7410  O OG1   . THR A 1 1168 ? 162.647 372.459 240.747 1.00 117.75 ? 1168 THR A OG1   1 
ATOM   7411  C CG2   . THR A 1 1168 ? 162.644 373.646 238.651 1.00 117.75 ? 1168 THR A CG2   1 
ATOM   7412  N N     . LEU A 1 1169 ? 162.468 370.241 236.892 1.00 115.65 ? 1169 LEU A N     1 
ATOM   7413  C CA    . LEU A 1 1169 ? 162.615 370.014 235.457 1.00 115.65 ? 1169 LEU A CA    1 
ATOM   7414  C C     . LEU A 1 1169 ? 161.309 369.538 234.830 1.00 115.65 ? 1169 LEU A C     1 
ATOM   7415  O O     . LEU A 1 1169 ? 160.934 369.994 233.743 1.00 115.65 ? 1169 LEU A O     1 
ATOM   7416  C CB    . LEU A 1 1169 ? 163.733 369.004 235.199 1.00 115.65 ? 1169 LEU A CB    1 
ATOM   7417  C CG    . LEU A 1 1169 ? 165.162 369.550 235.255 1.00 115.65 ? 1169 LEU A CG    1 
ATOM   7418  C CD1   . LEU A 1 1169 ? 166.157 368.429 235.513 1.00 115.65 ? 1169 LEU A CD1   1 
ATOM   7419  C CD2   . LEU A 1 1169 ? 165.505 370.293 233.973 1.00 115.65 ? 1169 LEU A CD2   1 
ATOM   7420  N N     . GLY A 1 1170 ? 160.605 368.626 235.495 1.00 118.90 ? 1170 GLY A N     1 
ATOM   7421  C CA    . GLY A 1 1170 ? 159.343 368.138 234.975 1.00 118.90 ? 1170 GLY A CA    1 
ATOM   7422  C C     . GLY A 1 1170 ? 159.171 366.636 235.065 1.00 118.90 ? 1170 GLY A C     1 
ATOM   7423  O O     . GLY A 1 1170 ? 158.182 366.090 234.567 1.00 118.90 ? 1170 GLY A O     1 
ATOM   7424  N N     . ALA A 1 1171 ? 160.130 365.955 235.690 1.00 125.79 ? 1171 ALA A N     1 
ATOM   7425  C CA    . ALA A 1 1171 ? 160.034 364.510 235.848 1.00 125.79 ? 1171 ALA A CA    1 
ATOM   7426  C C     . ALA A 1 1171 ? 158.858 364.150 236.748 1.00 125.79 ? 1171 ALA A C     1 
ATOM   7427  O O     . ALA A 1 1171 ? 158.596 364.814 237.755 1.00 125.79 ? 1171 ALA A O     1 
ATOM   7428  C CB    . ALA A 1 1171 ? 161.334 363.952 236.426 1.00 125.79 ? 1171 ALA A CB    1 
ATOM   7429  N N     . ASP A 1 1172 ? 158.146 363.087 236.379 1.00 136.65 ? 1172 ASP A N     1 
ATOM   7430  C CA    . ASP A 1 1172 ? 156.951 362.679 237.098 1.00 136.65 ? 1172 ASP A CA    1 
ATOM   7431  C C     . ASP A 1 1172 ? 157.309 361.696 238.213 1.00 136.65 ? 1172 ASP A C     1 
ATOM   7432  O O     . ASP A 1 1172 ? 158.479 361.467 238.528 1.00 136.65 ? 1172 ASP A O     1 
ATOM   7433  C CB    . ASP A 1 1172 ? 155.929 362.081 236.131 1.00 136.65 ? 1172 ASP A CB    1 
ATOM   7434  C CG    . ASP A 1 1172 ? 156.294 360.681 235.685 1.00 136.65 ? 1172 ASP A CG    1 
ATOM   7435  O OD1   . ASP A 1 1172 ? 155.884 359.717 236.365 1.00 136.65 ? 1172 ASP A OD1   1 
ATOM   7436  O OD2   . ASP A 1 1172 ? 156.991 360.544 234.658 1.00 136.65 ? 1172 ASP A OD2   1 
ATOM   7437  N N     . ASP A 1 1173 ? 156.282 361.102 238.814 1.00 142.32 ? 1173 ASP A N     1 
ATOM   7438  C CA    . ASP A 1 1173 ? 156.451 360.253 239.990 1.00 142.32 ? 1173 ASP A CA    1 
ATOM   7439  C C     . ASP A 1 1173 ? 157.203 358.954 239.704 1.00 142.32 ? 1173 ASP A C     1 
ATOM   7440  O O     . ASP A 1 1173 ? 157.863 358.409 240.589 1.00 142.32 ? 1173 ASP A O     1 
ATOM   7441  C CB    . ASP A 1 1173 ? 155.084 359.926 240.598 1.00 142.32 ? 1173 ASP A CB    1 
ATOM   7442  C CG    . ASP A 1 1173 ? 154.256 361.166 240.870 1.00 142.32 ? 1173 ASP A CG    1 
ATOM   7443  O OD1   . ASP A 1 1173 ? 154.692 362.271 240.483 1.00 142.32 ? 1173 ASP A OD1   1 
ATOM   7444  O OD2   . ASP A 1 1173 ? 153.169 361.037 241.471 1.00 142.32 ? 1173 ASP A OD2   1 
HETATM 7445  N N     . TPO A 1 1174 ? 157.101 358.459 238.474 1.00 145.39 ? 1174 TPO A N     1 
HETATM 7446  C CA    . TPO A 1 1174 ? 157.735 357.194 238.110 1.00 145.39 ? 1174 TPO A CA    1 
HETATM 7447  C CB    . TPO A 1 1174 ? 157.078 356.608 236.867 1.00 145.39 ? 1174 TPO A CB    1 
HETATM 7448  C CG2   . TPO A 1 1174 ? 155.568 356.511 237.092 1.00 145.39 ? 1174 TPO A CG2   1 
HETATM 7449  O OG1   . TPO A 1 1174 ? 157.342 357.440 235.736 1.00 145.39 ? 1174 TPO A OG1   1 
HETATM 7450  P P     . TPO A 1 1174 ? 157.902 356.493 234.561 1.00 145.39 ? 1174 TPO A P     1 
HETATM 7451  O O1P   . TPO A 1 1174 ? 157.137 355.227 234.532 1.00 145.39 ? 1174 TPO A O1P   1 
HETATM 7452  O O2P   . TPO A 1 1174 ? 157.734 357.247 233.148 1.00 145.39 ? 1174 TPO A O2P   1 
HETATM 7453  O O3P   . TPO A 1 1174 ? 159.460 356.176 234.816 1.00 145.39 ? 1174 TPO A O3P   1 
HETATM 7454  C C     . TPO A 1 1174 ? 159.236 357.358 237.890 1.00 145.39 ? 1174 TPO A C     1 
HETATM 7455  O O     . TPO A 1 1174 ? 159.996 356.396 237.999 1.00 145.39 ? 1174 TPO A O     1 
ATOM   7456  N N     . MET A 1 1175 ? 159.658 358.580 237.581 1.00 131.36 ? 1175 MET A N     1 
ATOM   7457  C CA    . MET A 1 1175 ? 161.073 358.869 237.386 1.00 131.36 ? 1175 MET A CA    1 
ATOM   7458  C C     . MET A 1 1175 ? 161.764 359.097 238.726 1.00 131.36 ? 1175 MET A C     1 
ATOM   7459  O O     . MET A 1 1175 ? 162.923 358.727 238.910 1.00 131.36 ? 1175 MET A O     1 
ATOM   7460  C CB    . MET A 1 1175 ? 161.254 360.089 236.480 1.00 131.36 ? 1175 MET A CB    1 
ATOM   7461  C CG    . MET A 1 1175 ? 161.113 359.784 234.997 1.00 131.36 ? 1175 MET A CG    1 
ATOM   7462  S SD    . MET A 1 1175 ? 161.980 358.279 234.513 1.00 131.36 ? 1175 MET A SD    1 
ATOM   7463  C CE    . MET A 1 1175 ? 161.807 358.345 232.731 1.00 131.36 ? 1175 MET A CE    1 
ATOM   7464  N N     . LEU A 1 1176 ? 161.040 359.711 239.664 1.00 126.78 ? 1176 LEU A N     1 
ATOM   7465  C CA    . LEU A 1 1176 ? 161.556 359.966 241.009 1.00 126.78 ? 1176 LEU A CA    1 
ATOM   7466  C C     . LEU A 1 1176 ? 161.283 358.748 241.894 1.00 126.78 ? 1176 LEU A C     1 
ATOM   7467  O O     . LEU A 1 1176 ? 160.485 358.774 242.833 1.00 126.78 ? 1176 LEU A O     1 
ATOM   7468  C CB    . LEU A 1 1176 ? 160.938 361.232 241.586 1.00 126.78 ? 1176 LEU A CB    1 
ATOM   7469  C CG    . LEU A 1 1176 ? 161.558 362.560 241.145 1.00 126.78 ? 1176 LEU A CG    1 
ATOM   7470  C CD1   . LEU A 1 1176 ? 160.775 363.170 239.996 1.00 126.78 ? 1176 LEU A CD1   1 
ATOM   7471  C CD2   . LEU A 1 1176 ? 161.629 363.530 242.313 1.00 126.78 ? 1176 LEU A CD2   1 
ATOM   7472  N N     . ALA A 1 1177 ? 161.974 357.658 241.572 1.00 119.49 ? 1177 ALA A N     1 
ATOM   7473  C CA    . ALA A 1 1177 ? 161.831 356.418 242.315 1.00 119.49 ? 1177 ALA A CA    1 
ATOM   7474  C C     . ALA A 1 1177 ? 162.500 356.532 243.683 1.00 119.49 ? 1177 ALA A C     1 
ATOM   7475  O O     . ALA A 1 1177 ? 163.305 357.430 243.944 1.00 119.49 ? 1177 ALA A O     1 
ATOM   7476  C CB    . ALA A 1 1177 ? 162.420 355.250 241.527 1.00 119.49 ? 1177 ALA A CB    1 
ATOM   7477  N N     . LYS A 1 1178 ? 162.154 355.600 244.568 1.00 119.12 ? 1178 LYS A N     1 
ATOM   7478  C CA    . LYS A 1 1178 ? 162.671 355.580 245.930 1.00 119.12 ? 1178 LYS A CA    1 
ATOM   7479  C C     . LYS A 1 1178 ? 163.299 354.221 246.198 1.00 119.12 ? 1178 LYS A C     1 
ATOM   7480  O O     . LYS A 1 1178 ? 162.712 353.187 245.862 1.00 119.12 ? 1178 LYS A O     1 
ATOM   7481  C CB    . LYS A 1 1178 ? 161.557 355.861 246.949 1.00 119.12 ? 1178 LYS A CB    1 
ATOM   7482  C CG    . LYS A 1 1178 ? 161.258 357.343 247.199 1.00 119.12 ? 1178 LYS A CG    1 
ATOM   7483  C CD    . LYS A 1 1178 ? 162.489 358.193 247.520 1.00 119.12 ? 1178 LYS A CD    1 
ATOM   7484  C CE    . LYS A 1 1178 ? 163.359 357.590 248.617 1.00 119.12 ? 1178 LYS A CE    1 
ATOM   7485  N NZ    . LYS A 1 1178 ? 164.599 358.388 248.819 1.00 119.12 ? 1178 LYS A NZ    1 
ATOM   7486  N N     . ASP A 1 1179 ? 164.486 354.224 246.795 1.00 121.20 ? 1179 ASP A N     1 
ATOM   7487  C CA    . ASP A 1 1179 ? 165.158 352.970 247.097 1.00 121.20 ? 1179 ASP A CA    1 
ATOM   7488  C C     . ASP A 1 1179 ? 164.425 352.246 248.224 1.00 121.20 ? 1179 ASP A C     1 
ATOM   7489  O O     . ASP A 1 1179 ? 164.048 352.871 249.223 1.00 121.20 ? 1179 ASP A O     1 
ATOM   7490  C CB    . ASP A 1 1179 ? 166.615 353.217 247.490 1.00 121.20 ? 1179 ASP A CB    1 
ATOM   7491  C CG    . ASP A 1 1179 ? 167.442 351.945 247.494 1.00 121.20 ? 1179 ASP A CG    1 
ATOM   7492  O OD1   . ASP A 1 1179 ? 167.273 351.124 248.420 1.00 121.20 ? 1179 ASP A OD1   1 
ATOM   7493  O OD2   . ASP A 1 1179 ? 168.262 351.767 246.569 1.00 121.20 ? 1179 ASP A OD2   1 
ATOM   7494  N N     . PRO A 1 1180 ? 164.194 350.937 248.094 1.00 122.62 ? 1180 PRO A N     1 
ATOM   7495  C CA    . PRO A 1 1180 ? 163.461 350.215 249.147 1.00 122.62 ? 1180 PRO A CA    1 
ATOM   7496  C C     . PRO A 1 1180 ? 164.146 350.232 250.504 1.00 122.62 ? 1180 PRO A C     1 
ATOM   7497  O O     . PRO A 1 1180 ? 163.454 350.248 251.530 1.00 122.62 ? 1180 PRO A O     1 
ATOM   7498  C CB    . PRO A 1 1180 ? 163.359 348.788 248.586 1.00 122.62 ? 1180 PRO A CB    1 
ATOM   7499  C CG    . PRO A 1 1180 ? 164.447 348.692 247.564 1.00 122.62 ? 1180 PRO A CG    1 
ATOM   7500  C CD    . PRO A 1 1180 ? 164.565 350.060 246.971 1.00 122.62 ? 1180 PRO A CD    1 
ATOM   7501  N N     . ALA A 1 1181 ? 165.482 350.229 250.551 1.00 123.42 ? 1181 ALA A N     1 
ATOM   7502  C CA    . ALA A 1 1181 ? 166.194 350.117 251.820 1.00 123.42 ? 1181 ALA A CA    1 
ATOM   7503  C C     . ALA A 1 1181 ? 167.402 351.045 251.906 1.00 123.42 ? 1181 ALA A C     1 
ATOM   7504  O O     . ALA A 1 1181 ? 168.259 350.851 252.774 1.00 123.42 ? 1181 ALA A O     1 
ATOM   7505  C CB    . ALA A 1 1181 ? 166.629 348.670 252.066 1.00 123.42 ? 1181 ALA A CB    1 
ATOM   7506  N N     . SER A 1 1182 ? 167.495 352.048 251.034 1.00 116.70 ? 1182 SER A N     1 
ATOM   7507  C CA    . SER A 1 1182 ? 168.595 353.004 251.089 1.00 116.70 ? 1182 SER A CA    1 
ATOM   7508  C C     . SER A 1 1182 ? 168.171 354.458 250.950 1.00 116.70 ? 1182 SER A C     1 
ATOM   7509  O O     . SER A 1 1182 ? 168.977 355.342 251.268 1.00 116.70 ? 1182 SER A O     1 
ATOM   7510  C CB    . SER A 1 1182 ? 169.637 352.692 250.003 1.00 116.70 ? 1182 SER A CB    1 
ATOM   7511  O OG    . SER A 1 1182 ? 170.940 353.049 250.430 1.00 116.70 ? 1182 SER A OG    1 
ATOM   7512  N N     . GLY A 1 1183 ? 166.952 354.741 250.501 1.00 111.62 ? 1183 GLY A N     1 
ATOM   7513  C CA    . GLY A 1 1183 ? 166.506 356.119 250.362 1.00 111.62 ? 1183 GLY A CA    1 
ATOM   7514  C C     . GLY A 1 1183 ? 167.300 356.927 249.359 1.00 111.62 ? 1183 GLY A C     1 
ATOM   7515  O O     . GLY A 1 1183 ? 167.581 358.108 249.599 1.00 111.62 ? 1183 GLY A O     1 
ATOM   7516  N N     . ILE A 1 1184 ? 167.670 356.316 248.236 1.00 108.09 ? 1184 ILE A N     1 
ATOM   7517  C CA    . ILE A 1 1184 ? 168.433 356.979 247.186 1.00 108.09 ? 1184 ILE A CA    1 
ATOM   7518  C C     . ILE A 1 1184 ? 167.724 356.758 245.858 1.00 108.09 ? 1184 ILE A C     1 
ATOM   7519  O O     . ILE A 1 1184 ? 167.317 355.635 245.541 1.00 108.09 ? 1184 ILE A O     1 
ATOM   7520  C CB    . ILE A 1 1184 ? 169.886 356.463 247.122 1.00 108.09 ? 1184 ILE A CB    1 
ATOM   7521  C CG1   . ILE A 1 1184 ? 170.602 356.704 248.453 1.00 108.09 ? 1184 ILE A CG1   1 
ATOM   7522  C CG2   . ILE A 1 1184 ? 170.641 357.129 245.981 1.00 108.09 ? 1184 ILE A CG2   1 
ATOM   7523  C CD1   . ILE A 1 1184 ? 171.062 358.132 248.655 1.00 108.09 ? 1184 ILE A CD1   1 
ATOM   7524  N N     . CYS A 1 1185 ? 167.571 357.831 245.086 1.00 107.20 ? 1185 CYS A N     1 
ATOM   7525  C CA    . CYS A 1 1185 ? 166.903 357.739 243.795 1.00 107.20 ? 1185 CYS A CA    1 
ATOM   7526  C C     . CYS A 1 1185 ? 167.677 356.831 242.847 1.00 107.20 ? 1185 CYS A C     1 
ATOM   7527  O O     . CYS A 1 1185 ? 168.911 356.834 242.824 1.00 107.20 ? 1185 CYS A O     1 
ATOM   7528  C CB    . CYS A 1 1185 ? 166.748 359.128 243.178 1.00 107.20 ? 1185 CYS A CB    1 
ATOM   7529  S SG    . CYS A 1 1185 ? 165.245 359.345 242.195 1.00 107.20 ? 1185 CYS A SG    1 
ATOM   7530  N N     . THR A 1 1186 ? 166.937 356.041 242.065 1.00 104.49 ? 1186 THR A N     1 
ATOM   7531  C CA    . THR A 1 1186 ? 167.570 355.151 241.096 1.00 104.49 ? 1186 THR A CA    1 
ATOM   7532  C C     . THR A 1 1186 ? 168.294 355.941 240.012 1.00 104.49 ? 1186 THR A C     1 
ATOM   7533  O O     . THR A 1 1186 ? 169.359 355.528 239.538 1.00 104.49 ? 1186 THR A O     1 
ATOM   7534  C CB    . THR A 1 1186 ? 166.527 354.222 240.474 1.00 104.49 ? 1186 THR A CB    1 
ATOM   7535  O OG1   . THR A 1 1186 ? 165.588 353.815 241.477 1.00 104.49 ? 1186 THR A OG1   1 
ATOM   7536  C CG2   . THR A 1 1186 ? 167.196 352.990 239.884 1.00 104.49 ? 1186 THR A CG2   1 
ATOM   7537  N N     . LEU A 1 1187 ? 167.724 357.076 239.600 1.00 101.77 ? 1187 LEU A N     1 
ATOM   7538  C CA    . LEU A 1 1187 ? 168.372 357.907 238.591 1.00 101.77 ? 1187 LEU A CA    1 
ATOM   7539  C C     . LEU A 1 1187 ? 169.709 358.444 239.082 1.00 101.77 ? 1187 LEU A C     1 
ATOM   7540  O O     . LEU A 1 1187 ? 170.624 358.659 238.278 1.00 101.77 ? 1187 LEU A O     1 
ATOM   7541  C CB    . LEU A 1 1187 ? 167.451 359.060 238.188 1.00 101.77 ? 1187 LEU A CB    1 
ATOM   7542  C CG    . LEU A 1 1187 ? 166.538 358.832 236.979 1.00 101.77 ? 1187 LEU A CG    1 
ATOM   7543  C CD1   . LEU A 1 1187 ? 165.568 357.686 237.223 1.00 101.77 ? 1187 LEU A CD1   1 
ATOM   7544  C CD2   . LEU A 1 1187 ? 165.786 360.107 236.634 1.00 101.77 ? 1187 LEU A CD2   1 
ATOM   7545  N N     . LEU A 1 1188 ? 169.841 358.673 240.392 1.00 97.23  ? 1188 LEU A N     1 
ATOM   7546  C CA    . LEU A 1 1188 ? 171.123 359.101 240.941 1.00 97.23  ? 1188 LEU A CA    1 
ATOM   7547  C C     . LEU A 1 1188 ? 172.182 358.022 240.740 1.00 97.23  ? 1188 LEU A C     1 
ATOM   7548  O O     . LEU A 1 1188 ? 173.320 358.321 240.360 1.00 97.23  ? 1188 LEU A O     1 
ATOM   7549  C CB    . LEU A 1 1188 ? 170.957 359.454 242.424 1.00 97.23  ? 1188 LEU A CB    1 
ATOM   7550  C CG    . LEU A 1 1188 ? 171.918 360.388 243.179 1.00 97.23  ? 1188 LEU A CG    1 
ATOM   7551  C CD1   . LEU A 1 1188 ? 171.560 360.408 244.657 1.00 97.23  ? 1188 LEU A CD1   1 
ATOM   7552  C CD2   . LEU A 1 1188 ? 173.390 360.037 243.011 1.00 97.23  ? 1188 LEU A CD2   1 
ATOM   7553  N N     . TYR A 1 1189 ? 171.822 356.758 240.981 1.00 98.49  ? 1189 TYR A N     1 
ATOM   7554  C CA    . TYR A 1 1189 ? 172.739 355.662 240.686 1.00 98.49  ? 1189 TYR A CA    1 
ATOM   7555  C C     . TYR A 1 1189 ? 173.039 355.581 239.195 1.00 98.49  ? 1189 TYR A C     1 
ATOM   7556  O O     . TYR A 1 1189 ? 174.192 355.385 238.794 1.00 98.49  ? 1189 TYR A O     1 
ATOM   7557  C CB    . TYR A 1 1189 ? 172.161 354.335 241.180 1.00 98.49  ? 1189 TYR A CB    1 
ATOM   7558  C CG    . TYR A 1 1189 ? 172.059 354.211 242.683 1.00 98.49  ? 1189 TYR A CG    1 
ATOM   7559  C CD1   . TYR A 1 1189 ? 173.180 354.359 243.488 1.00 98.49  ? 1189 TYR A CD1   1 
ATOM   7560  C CD2   . TYR A 1 1189 ? 170.846 353.922 243.295 1.00 98.49  ? 1189 TYR A CD2   1 
ATOM   7561  C CE1   . TYR A 1 1189 ? 173.093 354.240 244.861 1.00 98.49  ? 1189 TYR A CE1   1 
ATOM   7562  C CE2   . TYR A 1 1189 ? 170.751 353.797 244.668 1.00 98.49  ? 1189 TYR A CE2   1 
ATOM   7563  C CZ    . TYR A 1 1189 ? 171.878 353.956 245.446 1.00 98.49  ? 1189 TYR A CZ    1 
ATOM   7564  O OH    . TYR A 1 1189 ? 171.791 353.835 246.813 1.00 98.49  ? 1189 TYR A OH    1 
ATOM   7565  N N     . ASP A 1 1190 ? 172.011 355.731 238.357 1.00 98.43  ? 1190 ASP A N     1 
ATOM   7566  C CA    . ASP A 1 1190 ? 172.205 355.649 236.914 1.00 98.43  ? 1190 ASP A CA    1 
ATOM   7567  C C     . ASP A 1 1190 ? 172.908 356.876 236.349 1.00 98.43  ? 1190 ASP A C     1 
ATOM   7568  O O     . ASP A 1 1190 ? 173.380 356.832 235.208 1.00 98.43  ? 1190 ASP A O     1 
ATOM   7569  C CB    . ASP A 1 1190 ? 170.861 355.452 236.210 1.00 98.43  ? 1190 ASP A CB    1 
ATOM   7570  C CG    . ASP A 1 1190 ? 170.066 354.296 236.785 1.00 98.43  ? 1190 ASP A CG    1 
ATOM   7571  O OD1   . ASP A 1 1190 ? 170.677 353.259 237.118 1.00 98.43  ? 1190 ASP A OD1   1 
ATOM   7572  O OD2   . ASP A 1 1190 ? 168.829 354.424 236.902 1.00 98.43  ? 1190 ASP A OD2   1 
ATOM   7573  N N     . SER A 1 1191 ? 172.984 357.965 237.112 1.00 92.79  ? 1191 SER A N     1 
ATOM   7574  C CA    . SER A 1 1191 ? 173.630 359.174 236.622 1.00 92.79  ? 1191 SER A CA    1 
ATOM   7575  C C     . SER A 1 1191 ? 175.134 358.970 236.495 1.00 92.79  ? 1191 SER A C     1 
ATOM   7576  O O     . SER A 1 1191 ? 175.767 358.329 237.338 1.00 92.79  ? 1191 SER A O     1 
ATOM   7577  C CB    . SER A 1 1191 ? 173.334 360.348 237.556 1.00 92.79  ? 1191 SER A CB    1 
ATOM   7578  O OG    . SER A 1 1191 ? 171.959 360.687 237.529 1.00 92.79  ? 1191 SER A OG    1 
ATOM   7579  N N     . ALA A 1 1192 ? 175.705 359.521 235.427 1.00 84.19  ? 1192 ALA A N     1 
ATOM   7580  C CA    . ALA A 1 1192 ? 177.141 359.445 235.225 1.00 84.19  ? 1192 ALA A CA    1 
ATOM   7581  C C     . ALA A 1 1192 ? 177.866 360.310 236.255 1.00 84.19  ? 1192 ALA A C     1 
ATOM   7582  O O     . ALA A 1 1192 ? 177.314 361.299 236.746 1.00 84.19  ? 1192 ALA A O     1 
ATOM   7583  C CB    . ALA A 1 1192 ? 177.505 359.896 233.812 1.00 84.19  ? 1192 ALA A CB    1 
ATOM   7584  N N     . PRO A 1 1193 ? 179.113 359.954 236.610 1.00 80.59  ? 1193 PRO A N     1 
ATOM   7585  C CA    . PRO A 1 1193 ? 179.889 360.732 237.584 1.00 80.59  ? 1193 PRO A CA    1 
ATOM   7586  C C     . PRO A 1 1193 ? 180.148 362.169 237.135 1.00 80.59  ? 1193 PRO A C     1 
ATOM   7587  O O     . PRO A 1 1193 ? 179.834 363.105 237.870 1.00 80.59  ? 1193 PRO A O     1 
ATOM   7588  C CB    . PRO A 1 1193 ? 181.206 359.952 237.691 1.00 80.59  ? 1193 PRO A CB    1 
ATOM   7589  C CG    . PRO A 1 1193 ? 181.262 359.102 236.463 1.00 80.59  ? 1193 PRO A CG    1 
ATOM   7590  C CD    . PRO A 1 1193 ? 179.843 358.759 236.155 1.00 80.59  ? 1193 PRO A CD    1 
HETATM 7591  N N     . SEP A 1 1194 ? 180.712 362.336 235.943 1.00 79.51  ? 1194 SEP A N     1 
HETATM 7592  C CA    . SEP A 1 1194 ? 181.021 363.663 235.424 1.00 79.51  ? 1194 SEP A CA    1 
HETATM 7593  C CB    . SEP A 1 1194 ? 182.372 363.654 234.706 1.00 79.51  ? 1194 SEP A CB    1 
HETATM 7594  C C     . SEP A 1 1194 ? 179.930 364.162 234.482 1.00 79.51  ? 1194 SEP A C     1 
HETATM 7595  O O     . SEP A 1 1194 ? 179.153 363.373 233.943 1.00 79.51  ? 1194 SEP A O     1 
ATOM   7596  N N     . GLY A 1 1195 ? 179.878 365.476 234.288 1.00 76.95  ? 1195 GLY A N     1 
ATOM   7597  C CA    . GLY A 1 1195 ? 178.891 366.080 233.412 1.00 76.95  ? 1195 GLY A CA    1 
ATOM   7598  C C     . GLY A 1 1195 ? 178.207 367.289 234.019 1.00 76.95  ? 1195 GLY A C     1 
ATOM   7599  O O     . GLY A 1 1195 ? 178.460 367.642 235.171 1.00 76.95  ? 1195 GLY A O     1 
ATOM   7600  N N     . ARG A 1 1196 ? 177.336 367.930 233.235 1.00 75.93  ? 1196 ARG A N     1 
ATOM   7601  C CA    . ARG A 1 1196 ? 176.612 369.094 233.733 1.00 75.93  ? 1196 ARG A CA    1 
ATOM   7602  C C     . ARG A 1 1196 ? 175.631 368.716 234.835 1.00 75.93  ? 1196 ARG A C     1 
ATOM   7603  O O     . ARG A 1 1196 ? 175.398 369.506 235.757 1.00 75.93  ? 1196 ARG A O     1 
ATOM   7604  C CB    . ARG A 1 1196 ? 175.879 369.788 232.585 1.00 75.93  ? 1196 ARG A CB    1 
ATOM   7605  N N     . PHE A 1 1197 ? 175.050 367.518 234.760 1.00 78.27  ? 1197 PHE A N     1 
ATOM   7606  C CA    . PHE A 1 1197 ? 174.125 367.027 235.774 1.00 78.27  ? 1197 PHE A CA    1 
ATOM   7607  C C     . PHE A 1 1197 ? 174.674 365.779 236.454 1.00 78.27  ? 1197 PHE A C     1 
ATOM   7608  O O     . PHE A 1 1197 ? 173.911 364.907 236.877 1.00 78.27  ? 1197 PHE A O     1 
ATOM   7609  C CB    . PHE A 1 1197 ? 172.749 366.748 235.170 1.00 78.27  ? 1197 PHE A CB    1 
ATOM   7610  N N     . GLY A 1 1198 ? 175.999 365.681 236.564 1.00 82.58  ? 1198 GLY A N     1 
ATOM   7611  C CA    . GLY A 1 1198 ? 176.616 364.522 237.170 1.00 82.58  ? 1198 GLY A CA    1 
ATOM   7612  C C     . GLY A 1 1198 ? 176.464 364.494 238.679 1.00 82.58  ? 1198 GLY A C     1 
ATOM   7613  O O     . GLY A 1 1198 ? 176.087 365.475 239.319 1.00 82.58  ? 1198 GLY A O     1 
ATOM   7614  N N     . THR A 1 1199 ? 176.771 363.328 239.250 1.00 86.83  ? 1199 THR A N     1 
ATOM   7615  C CA    . THR A 1 1199 ? 176.640 363.151 240.693 1.00 86.83  ? 1199 THR A CA    1 
ATOM   7616  C C     . THR A 1 1199 ? 177.668 363.972 241.461 1.00 86.83  ? 1199 THR A C     1 
ATOM   7617  O O     . THR A 1 1199 ? 177.408 364.377 242.600 1.00 86.83  ? 1199 THR A O     1 
ATOM   7618  C CB    . THR A 1 1199 ? 176.776 361.672 241.056 1.00 86.83  ? 1199 THR A CB    1 
ATOM   7619  O OG1   . THR A 1 1199 ? 178.092 361.214 240.718 1.00 86.83  ? 1199 THR A OG1   1 
ATOM   7620  C CG2   . THR A 1 1199 ? 175.751 360.843 240.298 1.00 86.83  ? 1199 THR A CG2   1 
ATOM   7621  N N     . MET A 1 1200 ? 178.834 364.224 240.862 1.00 83.42  ? 1200 MET A N     1 
ATOM   7622  C CA    . MET A 1 1200 ? 179.883 364.953 241.568 1.00 83.42  ? 1200 MET A CA    1 
ATOM   7623  C C     . MET A 1 1200 ? 179.480 366.398 241.833 1.00 83.42  ? 1200 MET A C     1 
ATOM   7624  O O     . MET A 1 1200 ? 179.839 366.964 242.870 1.00 83.42  ? 1200 MET A O     1 
ATOM   7625  C CB    . MET A 1 1200 ? 181.194 364.891 240.786 1.00 83.42  ? 1200 MET A CB    1 
ATOM   7626  C CG    . MET A 1 1200 ? 181.697 363.479 240.546 1.00 83.42  ? 1200 MET A CG    1 
ATOM   7627  S SD    . MET A 1 1200 ? 182.647 362.867 241.952 1.00 83.42  ? 1200 MET A SD    1 
ATOM   7628  C CE    . MET A 1 1200 ? 184.288 362.769 241.247 1.00 83.42  ? 1200 MET A CE    1 
ATOM   7629  N N     . THR A 1 1201 ? 178.743 367.016 240.908 1.00 90.70  ? 1201 THR A N     1 
ATOM   7630  C CA    . THR A 1 1201 ? 178.273 368.380 241.140 1.00 90.70  ? 1201 THR A CA    1 
ATOM   7631  C C     . THR A 1 1201 ? 177.330 368.442 242.336 1.00 90.70  ? 1201 THR A C     1 
ATOM   7632  O O     . THR A 1 1201 ? 177.453 369.328 243.192 1.00 90.70  ? 1201 THR A O     1 
ATOM   7633  C CB    . THR A 1 1201 ? 177.585 368.921 239.887 1.00 90.70  ? 1201 THR A CB    1 
ATOM   7634  O OG1   . THR A 1 1201 ? 176.535 368.029 239.492 1.00 90.70  ? 1201 THR A OG1   1 
ATOM   7635  C CG2   . THR A 1 1201 ? 178.584 369.055 238.746 1.00 90.70  ? 1201 THR A CG2   1 
ATOM   7636  N N     . TYR A 1 1202 ? 176.386 367.500 242.418 1.00 94.34  ? 1202 TYR A N     1 
ATOM   7637  C CA    . TYR A 1 1202 ? 175.471 367.463 243.554 1.00 94.34  ? 1202 TYR A CA    1 
ATOM   7638  C C     . TYR A 1 1202 ? 176.216 367.170 244.850 1.00 94.34  ? 1202 TYR A C     1 
ATOM   7639  O O     . TYR A 1 1202 ? 175.901 367.744 245.900 1.00 94.34  ? 1202 TYR A O     1 
ATOM   7640  C CB    . TYR A 1 1202 ? 174.378 366.422 243.315 1.00 94.34  ? 1202 TYR A CB    1 
ATOM   7641  C CG    . TYR A 1 1202 ? 173.533 366.690 242.090 1.00 94.34  ? 1202 TYR A CG    1 
ATOM   7642  C CD1   . TYR A 1 1202 ? 172.798 367.863 241.972 1.00 94.34  ? 1202 TYR A CD1   1 
ATOM   7643  C CD2   . TYR A 1 1202 ? 173.469 365.770 241.052 1.00 94.34  ? 1202 TYR A CD2   1 
ATOM   7644  C CE1   . TYR A 1 1202 ? 172.024 368.112 240.854 1.00 94.34  ? 1202 TYR A CE1   1 
ATOM   7645  C CE2   . TYR A 1 1202 ? 172.698 366.010 239.930 1.00 94.34  ? 1202 TYR A CE2   1 
ATOM   7646  C CZ    . TYR A 1 1202 ? 171.978 367.182 239.837 1.00 94.34  ? 1202 TYR A CZ    1 
ATOM   7647  O OH    . TYR A 1 1202 ? 171.208 367.426 238.722 1.00 94.34  ? 1202 TYR A OH    1 
ATOM   7648  N N     . LEU A 1 1203 ? 177.204 366.273 244.798 1.00 91.33  ? 1203 LEU A N     1 
ATOM   7649  C CA    . LEU A 1 1203 ? 177.990 365.973 245.990 1.00 91.33  ? 1203 LEU A CA    1 
ATOM   7650  C C     . LEU A 1 1203 ? 178.778 367.193 246.453 1.00 91.33  ? 1203 LEU A C     1 
ATOM   7651  O O     . LEU A 1 1203 ? 178.870 367.459 247.657 1.00 91.33  ? 1203 LEU A O     1 
ATOM   7652  C CB    . LEU A 1 1203 ? 178.927 364.797 245.719 1.00 91.33  ? 1203 LEU A CB    1 
ATOM   7653  C CG    . LEU A 1 1203 ? 178.281 363.412 245.774 1.00 91.33  ? 1203 LEU A CG    1 
ATOM   7654  C CD1   . LEU A 1 1203 ? 178.953 362.470 244.790 1.00 91.33  ? 1203 LEU A CD1   1 
ATOM   7655  C CD2   . LEU A 1 1203 ? 178.334 362.848 247.185 1.00 91.33  ? 1203 LEU A CD2   1 
ATOM   7656  N N     . SER A 1 1204 ? 179.355 367.943 245.512 1.00 92.96  ? 1204 SER A N     1 
ATOM   7657  C CA    . SER A 1 1204 ? 180.065 369.168 245.864 1.00 92.96  ? 1204 SER A CA    1 
ATOM   7658  C C     . SER A 1 1204 ? 179.121 370.186 246.485 1.00 92.96  ? 1204 SER A C     1 
ATOM   7659  O O     . SER A 1 1204 ? 179.460 370.832 247.486 1.00 92.96  ? 1204 SER A O     1 
ATOM   7660  C CB    . SER A 1 1204 ? 180.741 369.758 244.626 1.00 92.96  ? 1204 SER A CB    1 
ATOM   7661  O OG    . SER A 1 1204 ? 181.522 368.788 243.951 1.00 92.96  ? 1204 SER A OG    1 
ATOM   7662  N N     . LYS A 1 1205 ? 177.927 370.341 245.905 1.00 98.02  ? 1205 LYS A N     1 
ATOM   7663  C CA    . LYS A 1 1205 ? 176.948 371.267 246.465 1.00 98.02  ? 1205 LYS A CA    1 
ATOM   7664  C C     . LYS A 1 1205 ? 176.567 370.869 247.885 1.00 98.02  ? 1205 LYS A C     1 
ATOM   7665  O O     . LYS A 1 1205 ? 176.506 371.718 248.780 1.00 98.02  ? 1205 LYS A O     1 
ATOM   7666  C CB    . LYS A 1 1205 ? 175.704 371.319 245.578 1.00 98.02  ? 1205 LYS A CB    1 
ATOM   7667  C CG    . LYS A 1 1205 ? 175.888 372.064 244.268 1.00 98.02  ? 1205 LYS A CG    1 
ATOM   7668  C CD    . LYS A 1 1205 ? 174.545 372.323 243.603 1.00 98.02  ? 1205 LYS A CD    1 
ATOM   7669  C CE    . LYS A 1 1205 ? 174.706 372.663 242.132 1.00 98.02  ? 1205 LYS A CE    1 
ATOM   7670  N NZ    . LYS A 1 1205 ? 175.093 371.472 241.326 1.00 98.02  ? 1205 LYS A NZ    1 
ATOM   7671  N N     . ALA A 1 1206 ? 176.320 369.577 248.110 1.00 98.33  ? 1206 ALA A N     1 
ATOM   7672  C CA    . ALA A 1 1206 ? 175.926 369.115 249.437 1.00 98.33  ? 1206 ALA A CA    1 
ATOM   7673  C C     . ALA A 1 1206 ? 177.057 369.282 250.446 1.00 98.33  ? 1206 ALA A C     1 
ATOM   7674  O O     . ALA A 1 1206 ? 176.820 369.679 251.593 1.00 98.33  ? 1206 ALA A O     1 
ATOM   7675  C CB    . ALA A 1 1206 ? 175.477 367.657 249.369 1.00 98.33  ? 1206 ALA A CB    1 
ATOM   7676  N N     . ALA A 1 1207 ? 178.292 368.974 250.041 1.00 99.76  ? 1207 ALA A N     1 
ATOM   7677  C CA    . ALA A 1 1207 ? 179.427 369.137 250.943 1.00 99.76  ? 1207 ALA A CA    1 
ATOM   7678  C C     . ALA A 1 1207 ? 179.631 370.600 251.312 1.00 99.76  ? 1207 ALA A C     1 
ATOM   7679  O O     . ALA A 1 1207 ? 179.874 370.925 252.481 1.00 99.76  ? 1207 ALA A O     1 
ATOM   7680  C CB    . ALA A 1 1207 ? 180.691 368.561 250.306 1.00 99.76  ? 1207 ALA A CB    1 
ATOM   7681  N N     . ALA A 1 1208 ? 179.530 371.500 250.330 1.00 102.45 ? 1208 ALA A N     1 
ATOM   7682  C CA    . ALA A 1 1208 ? 179.670 372.922 250.623 1.00 102.45 ? 1208 ALA A CA    1 
ATOM   7683  C C     . ALA A 1 1208 ? 178.530 373.417 251.504 1.00 102.45 ? 1208 ALA A C     1 
ATOM   7684  O O     . ALA A 1 1208 ? 178.739 374.261 252.384 1.00 102.45 ? 1208 ALA A O     1 
ATOM   7685  C CB    . ALA A 1 1208 ? 179.744 373.721 249.323 1.00 102.45 ? 1208 ALA A CB    1 
ATOM   7686  N N     . THR A 1 1209 ? 177.315 372.903 251.288 1.00 104.34 ? 1209 THR A N     1 
ATOM   7687  C CA    . THR A 1 1209 ? 176.192 373.272 252.144 1.00 104.34 ? 1209 THR A CA    1 
ATOM   7688  C C     . THR A 1 1209 ? 176.425 372.824 253.581 1.00 104.34 ? 1209 THR A C     1 
ATOM   7689  O O     . THR A 1 1209 ? 176.153 373.575 254.524 1.00 104.34 ? 1209 THR A O     1 
ATOM   7690  C CB    . THR A 1 1209 ? 174.895 372.669 251.603 1.00 104.34 ? 1209 THR A CB    1 
ATOM   7691  O OG1   . THR A 1 1209 ? 174.902 372.714 250.171 1.00 104.34 ? 1209 THR A OG1   1 
ATOM   7692  C CG2   . THR A 1 1209 ? 173.692 373.443 252.122 1.00 104.34 ? 1209 THR A CG2   1 
ATOM   7693  N N     . TYR A 1 1210 ? 176.926 371.601 253.767 1.00 106.79 ? 1210 TYR A N     1 
ATOM   7694  C CA    . TYR A 1 1210 ? 177.229 371.120 255.113 1.00 106.79 ? 1210 TYR A CA    1 
ATOM   7695  C C     . TYR A 1 1210 ? 178.322 371.959 255.764 1.00 106.79 ? 1210 TYR A C     1 
ATOM   7696  O O     . TYR A 1 1210 ? 178.231 372.305 256.950 1.00 106.79 ? 1210 TYR A O     1 
ATOM   7697  C CB    . TYR A 1 1210 ? 177.638 369.647 255.060 1.00 106.79 ? 1210 TYR A CB    1 
ATOM   7698  C CG    . TYR A 1 1210 ? 177.553 368.929 256.390 1.00 106.79 ? 1210 TYR A CG    1 
ATOM   7699  C CD1   . TYR A 1 1210 ? 178.565 369.050 257.334 1.00 106.79 ? 1210 TYR A CD1   1 
ATOM   7700  C CD2   . TYR A 1 1210 ? 176.462 368.127 256.698 1.00 106.79 ? 1210 TYR A CD2   1 
ATOM   7701  C CE1   . TYR A 1 1210 ? 178.491 368.395 258.549 1.00 106.79 ? 1210 TYR A CE1   1 
ATOM   7702  C CE2   . TYR A 1 1210 ? 176.380 367.468 257.910 1.00 106.79 ? 1210 TYR A CE2   1 
ATOM   7703  C CZ    . TYR A 1 1210 ? 177.396 367.605 258.831 1.00 106.79 ? 1210 TYR A CZ    1 
ATOM   7704  O OH    . TYR A 1 1210 ? 177.318 366.951 260.039 1.00 106.79 ? 1210 TYR A OH    1 
ATOM   7705  N N     . VAL A 1 1211 ? 179.362 372.301 255.000 1.00 109.56 ? 1211 VAL A N     1 
ATOM   7706  C CA    . VAL A 1 1211 ? 180.443 373.125 255.535 1.00 109.56 ? 1211 VAL A CA    1 
ATOM   7707  C C     . VAL A 1 1211 ? 179.911 374.488 255.960 1.00 109.56 ? 1211 VAL A C     1 
ATOM   7708  O O     . VAL A 1 1211 ? 180.253 374.997 257.034 1.00 109.56 ? 1211 VAL A O     1 
ATOM   7709  C CB    . VAL A 1 1211 ? 181.580 373.248 254.503 1.00 109.56 ? 1211 VAL A CB    1 
ATOM   7710  C CG1   . VAL A 1 1211 ? 182.555 374.339 254.906 1.00 109.56 ? 1211 VAL A CG1   1 
ATOM   7711  C CG2   . VAL A 1 1211 ? 182.303 371.918 254.355 1.00 109.56 ? 1211 VAL A CG2   1 
ATOM   7712  N N     . GLN A 1 1212 ? 179.054 375.094 255.133 1.00 116.43 ? 1212 GLN A N     1 
ATOM   7713  C CA    . GLN A 1 1212 ? 178.447 376.371 255.496 1.00 116.43 ? 1212 GLN A CA    1 
ATOM   7714  C C     . GLN A 1 1212 ? 177.580 376.235 256.742 1.00 116.43 ? 1212 GLN A C     1 
ATOM   7715  O O     . GLN A 1 1212 ? 177.573 377.123 257.602 1.00 116.43 ? 1212 GLN A O     1 
ATOM   7716  C CB    . GLN A 1 1212 ? 177.626 376.912 254.326 1.00 116.43 ? 1212 GLN A CB    1 
ATOM   7717  C CG    . GLN A 1 1212 ? 178.459 377.525 253.212 1.00 116.43 ? 1212 GLN A CG    1 
ATOM   7718  C CD    . GLN A 1 1212 ? 178.946 378.921 253.550 1.00 116.43 ? 1212 GLN A CD    1 
ATOM   7719  O OE1   . GLN A 1 1212 ? 179.930 379.090 254.269 1.00 116.43 ? 1212 GLN A OE1   1 
ATOM   7720  N NE2   . GLN A 1 1212 ? 178.256 379.930 253.031 1.00 116.43 ? 1212 GLN A NE2   1 
ATOM   7721  N N     . GLU A 1 1213 ? 176.836 375.131 256.852 1.00 114.79 ? 1213 GLU A N     1 
ATOM   7722  C CA    . GLU A 1 1213 ? 176.052 374.873 258.053 1.00 114.79 ? 1213 GLU A CA    1 
ATOM   7723  C C     . GLU A 1 1213 ? 176.929 374.710 259.285 1.00 114.79 ? 1213 GLU A C     1 
ATOM   7724  O O     . GLU A 1 1213 ? 176.464 374.966 260.402 1.00 114.79 ? 1213 GLU A O     1 
ATOM   7725  C CB    . GLU A 1 1213 ? 175.190 373.622 257.866 1.00 114.79 ? 1213 GLU A CB    1 
ATOM   7726  C CG    . GLU A 1 1213 ? 174.008 373.806 256.929 1.00 114.79 ? 1213 GLU A CG    1 
ATOM   7727  C CD    . GLU A 1 1213 ? 173.570 372.504 256.287 1.00 114.79 ? 1213 GLU A CD    1 
ATOM   7728  O OE1   . GLU A 1 1213 ? 173.865 371.431 256.854 1.00 114.79 ? 1213 GLU A OE1   1 
ATOM   7729  O OE2   . GLU A 1 1213 ? 172.929 372.553 255.216 1.00 114.79 ? 1213 GLU A OE2   1 
ATOM   7730  N N     . PHE A 1 1214 ? 178.180 374.293 259.112 1.00 114.16 ? 1214 PHE A N     1 
ATOM   7731  C CA    . PHE A 1 1214 ? 179.114 374.127 260.219 1.00 114.16 ? 1214 PHE A CA    1 
ATOM   7732  C C     . PHE A 1 1214 ? 180.234 375.161 260.155 1.00 114.16 ? 1214 PHE A C     1 
ATOM   7733  O O     . PHE A 1 1214 ? 181.400 374.861 260.417 1.00 114.16 ? 1214 PHE A O     1 
ATOM   7734  C CB    . PHE A 1 1214 ? 179.682 372.710 260.244 1.00 114.16 ? 1214 PHE A CB    1 
ATOM   7735  C CG    . PHE A 1 1214 ? 178.870 371.748 261.066 1.00 114.16 ? 1214 PHE A CG    1 
ATOM   7736  C CD1   . PHE A 1 1214 ? 177.512 371.595 260.838 1.00 114.16 ? 1214 PHE A CD1   1 
ATOM   7737  C CD2   . PHE A 1 1214 ? 179.463 371.003 262.071 1.00 114.16 ? 1214 PHE A CD2   1 
ATOM   7738  C CE1   . PHE A 1 1214 ? 176.763 370.713 261.594 1.00 114.16 ? 1214 PHE A CE1   1 
ATOM   7739  C CE2   . PHE A 1 1214 ? 178.719 370.120 262.831 1.00 114.16 ? 1214 PHE A CE2   1 
ATOM   7740  C CZ    . PHE A 1 1214 ? 177.367 369.975 262.592 1.00 114.16 ? 1214 PHE A CZ    1 
ATOM   7741  N N     . LEU A 1 1215 ? 179.886 376.391 259.805 1.00 127.30 ? 1215 LEU A N     1 
ATOM   7742  C CA    . LEU A 1 1215 ? 180.796 377.525 259.790 1.00 127.30 ? 1215 LEU A CA    1 
ATOM   7743  C C     . LEU A 1 1215 ? 180.132 378.704 260.483 1.00 127.30 ? 1215 LEU A C     1 
ATOM   7744  O O     . LEU A 1 1215 ? 178.901 378.794 260.526 1.00 127.30 ? 1215 LEU A O     1 
ATOM   7745  C CB    . LEU A 1 1215 ? 181.187 377.913 258.356 1.00 127.30 ? 1215 LEU A CB    1 
ATOM   7746  C CG    . LEU A 1 1215 ? 182.407 377.209 257.755 1.00 127.30 ? 1215 LEU A CG    1 
ATOM   7747  C CD1   . LEU A 1 1215 ? 182.626 377.650 256.316 1.00 127.30 ? 1215 LEU A CD1   1 
ATOM   7748  C CD2   . LEU A 1 1215 ? 183.654 377.448 258.592 1.00 127.30 ? 1215 LEU A CD2   1 
ATOM   7749  N N     . PRO A 1 1216 ? 180.923 379.632 261.042 1.00 142.22 ? 1216 PRO A N     1 
ATOM   7750  C CA    . PRO A 1 1216 ? 180.324 380.775 261.747 1.00 142.22 ? 1216 PRO A CA    1 
ATOM   7751  C C     . PRO A 1 1216 ? 179.689 381.793 260.811 1.00 142.22 ? 1216 PRO A C     1 
ATOM   7752  O O     . PRO A 1 1216 ? 180.184 382.918 260.681 1.00 142.22 ? 1216 PRO A O     1 
ATOM   7753  C CB    . PRO A 1 1216 ? 181.512 381.378 262.507 1.00 142.22 ? 1216 PRO A CB    1 
ATOM   7754  C CG    . PRO A 1 1216 ? 182.706 380.976 261.722 1.00 142.22 ? 1216 PRO A CG    1 
ATOM   7755  C CD    . PRO A 1 1216 ? 182.393 379.627 261.142 1.00 142.22 ? 1216 PRO A CD    1 
ATOM   7756  N N     . HIS A 1 1217 ? 178.598 381.400 260.157 1.00 149.96 ? 1217 HIS A N     1 
ATOM   7757  C CA    . HIS A 1 1217 ? 177.792 382.296 259.326 1.00 149.96 ? 1217 HIS A CA    1 
ATOM   7758  C C     . HIS A 1 1217 ? 178.584 382.965 258.203 1.00 149.96 ? 1217 HIS A C     1 
ATOM   7759  O O     . HIS A 1 1217 ? 178.256 384.075 257.783 1.00 149.96 ? 1217 HIS A O     1 
ATOM   7760  C CB    . HIS A 1 1217 ? 177.131 383.370 260.196 1.00 149.96 ? 1217 HIS A CB    1 
ATOM   7761  C CG    . HIS A 1 1217 ? 176.406 382.823 261.386 1.00 149.96 ? 1217 HIS A CG    1 
ATOM   7762  N ND1   . HIS A 1 1217 ? 175.885 381.547 261.420 1.00 149.96 ? 1217 HIS A ND1   1 
ATOM   7763  C CD2   . HIS A 1 1217 ? 176.115 383.380 262.585 1.00 149.96 ? 1217 HIS A CD2   1 
ATOM   7764  C CE1   . HIS A 1 1217 ? 175.305 381.342 262.588 1.00 149.96 ? 1217 HIS A CE1   1 
ATOM   7765  N NE2   . HIS A 1 1217 ? 175.430 382.438 263.314 1.00 149.96 ? 1217 HIS A NE2   1 
HETATM 7766  N N     . SEP A 1 1218 ? 179.620 382.288 257.718 1.00 147.99 ? 1218 SEP A N     1 
HETATM 7767  C CA    . SEP A 1 1218 ? 180.431 382.813 256.624 1.00 147.99 ? 1218 SEP A CA    1 
HETATM 7768  C CB    . SEP A 1 1218 ? 181.379 383.903 257.129 1.00 147.99 ? 1218 SEP A CB    1 
HETATM 7769  O OG    . SEP A 1 1218 ? 182.092 384.491 256.054 1.00 147.99 ? 1218 SEP A OG    1 
HETATM 7770  C C     . SEP A 1 1218 ? 181.228 381.704 255.949 1.00 147.99 ? 1218 SEP A C     1 
HETATM 7771  O O     . SEP A 1 1218 ? 181.250 380.569 256.420 1.00 147.99 ? 1218 SEP A O     1 
HETATM 7772  P P     . SEP A 1 1218 ? 183.343 385.337 256.611 1.00 147.99 ? 1218 SEP A P     1 
HETATM 7773  O O1P   . SEP A 1 1218 ? 183.826 386.383 255.487 1.00 147.99 ? 1218 SEP A O1P   1 
HETATM 7774  O O2P   . SEP A 1 1218 ? 182.902 386.138 257.936 1.00 147.99 ? 1218 SEP A O2P   1 
HETATM 7775  O O3P   . SEP A 1 1218 ? 184.551 384.334 256.969 1.00 147.99 ? 1218 SEP A O3P   1 
ATOM   7776  N N     . ILE A 1 1219 ? 181.882 382.042 254.842 1.00 138.35 ? 1219 ILE A N     1 
ATOM   7777  C CA    . ILE A 1 1219 ? 182.718 381.087 254.128 1.00 138.35 ? 1219 ILE A CA    1 
ATOM   7778  C C     . ILE A 1 1219 ? 184.188 381.447 254.332 1.00 138.35 ? 1219 ILE A C     1 
ATOM   7779  O O     . ILE A 1 1219 ? 184.550 382.623 254.390 1.00 138.35 ? 1219 ILE A O     1 
ATOM   7780  C CB    . ILE A 1 1219 ? 182.347 381.028 252.627 1.00 138.35 ? 1219 ILE A CB    1 
ATOM   7781  C CG1   . ILE A 1 1219 ? 183.080 379.878 251.932 1.00 138.35 ? 1219 ILE A CG1   1 
ATOM   7782  C CG2   . ILE A 1 1219 ? 182.631 382.358 251.940 1.00 138.35 ? 1219 ILE A CG2   1 
ATOM   7783  C CD1   . ILE A 1 1219 ? 182.429 378.527 252.133 1.00 138.35 ? 1219 ILE A CD1   1 
ATOM   7784  N N     . CYS A 1 1220 ? 185.031 380.426 254.462 1.00 130.70 ? 1220 CYS A N     1 
ATOM   7785  C CA    . CYS A 1 1220 ? 186.460 380.595 254.690 1.00 130.70 ? 1220 CYS A CA    1 
ATOM   7786  C C     . CYS A 1 1220 ? 187.272 379.833 253.649 1.00 130.70 ? 1220 CYS A C     1 
ATOM   7787  O O     . CYS A 1 1220 ? 188.261 379.169 253.966 1.00 130.70 ? 1220 CYS A O     1 
ATOM   7788  C CB    . CYS A 1 1220 ? 186.840 380.151 256.100 1.00 130.70 ? 1220 CYS A CB    1 
ATOM   7789  S SG    . CYS A 1 1220 ? 186.404 378.440 256.484 1.00 130.70 ? 1220 CYS A SG    1 
ATOM   7790  N N     . ALA A 1 1221 ? 186.865 379.929 252.385 1.00 127.92 ? 1221 ALA A N     1 
ATOM   7791  C CA    . ALA A 1 1221 ? 187.526 379.241 251.282 1.00 127.92 ? 1221 ALA A CA    1 
ATOM   7792  C C     . ALA A 1 1221 ? 188.149 380.276 250.353 1.00 127.92 ? 1221 ALA A C     1 
ATOM   7793  O O     . ALA A 1 1221 ? 187.433 381.045 249.703 1.00 127.92 ? 1221 ALA A O     1 
ATOM   7794  C CB    . ALA A 1 1221 ? 186.540 378.352 250.528 1.00 127.92 ? 1221 ALA A CB    1 
ATOM   7795  N N     . MET A 1 1222 ? 189.479 380.297 250.295 1.00 130.99 ? 1222 MET A N     1 
ATOM   7796  C CA    . MET A 1 1222 ? 190.190 381.120 249.327 1.00 130.99 ? 1222 MET A CA    1 
ATOM   7797  C C     . MET A 1 1222 ? 191.469 380.403 248.922 1.00 130.99 ? 1222 MET A C     1 
ATOM   7798  O O     . MET A 1 1222 ? 191.974 379.537 249.641 1.00 130.99 ? 1222 MET A O     1 
ATOM   7799  C CB    . MET A 1 1222 ? 190.522 382.518 249.870 1.00 130.99 ? 1222 MET A CB    1 
ATOM   7800  C CG    . MET A 1 1222 ? 191.428 382.532 251.095 1.00 130.99 ? 1222 MET A CG    1 
ATOM   7801  S SD    . MET A 1 1222 ? 190.822 381.547 252.475 1.00 130.99 ? 1222 MET A SD    1 
ATOM   7802  C CE    . MET A 1 1222 ? 189.295 382.408 252.838 1.00 130.99 ? 1222 MET A CE    1 
ATOM   7803  N N     . GLN A 1 1223 ? 191.989 380.780 247.758 1.00 135.49 ? 1223 GLN A N     1 
ATOM   7804  C CA    . GLN A 1 1223 ? 193.229 380.204 247.248 1.00 135.49 ? 1223 GLN A CA    1 
ATOM   7805  C C     . GLN A 1 1223 ? 193.869 381.122 246.213 1.00 135.49 ? 1223 GLN A C     1 
ATOM   7806  O O     . GLN A 1 1223 ? 193.203 381.969 245.618 1.00 135.49 ? 1223 GLN A O     1 
ATOM   7807  C CB    . GLN A 1 1223 ? 192.973 378.823 246.641 1.00 135.49 ? 1223 GLN A CB    1 
ATOM   7808  C CG    . GLN A 1 1223 ? 194.171 377.886 246.694 1.00 135.49 ? 1223 GLN A CG    1 
ATOM   7809  C CD    . GLN A 1 1223 ? 194.443 377.361 248.091 1.00 135.49 ? 1223 GLN A CD    1 
ATOM   7810  O OE1   . GLN A 1 1223 ? 195.064 378.036 248.912 1.00 135.49 ? 1223 GLN A OE1   1 
ATOM   7811  N NE2   . GLN A 1 1223 ? 193.977 376.148 248.367 1.00 135.49 ? 1223 GLN A NE2   1 
ATOM   7812  O OXT   . GLN A 1 1223 ? 195.068 381.038 245.946 1.00 135.49 ? 1223 GLN A OXT   1 
ATOM   7813  N N     . SER B 2 12   ? 215.246 331.837 208.364 1.00 107.56 ? 12   SER C N     1 
ATOM   7814  C CA    . SER B 2 12   ? 214.412 330.836 209.018 1.00 107.56 ? 12   SER C CA    1 
ATOM   7815  C C     . SER B 2 12   ? 214.166 331.197 210.479 1.00 107.56 ? 12   SER C C     1 
ATOM   7816  O O     . SER B 2 12   ? 214.591 332.253 210.947 1.00 107.56 ? 12   SER C O     1 
ATOM   7817  C CB    . SER B 2 12   ? 215.057 329.452 208.919 1.00 107.56 ? 12   SER C CB    1 
ATOM   7818  O OG    . SER B 2 12   ? 215.883 329.193 210.040 1.00 107.56 ? 12   SER C OG    1 
ATOM   7819  N N     . ALA B 2 13   ? 213.471 330.309 211.196 1.00 103.14 ? 13   ALA C N     1 
ATOM   7820  C CA    . ALA B 2 13   ? 213.188 330.558 212.605 1.00 103.14 ? 13   ALA C CA    1 
ATOM   7821  C C     . ALA B 2 13   ? 214.453 330.508 213.452 1.00 103.14 ? 13   ALA C C     1 
ATOM   7822  O O     . ALA B 2 13   ? 214.537 331.191 214.479 1.00 103.14 ? 13   ALA C O     1 
ATOM   7823  C CB    . ALA B 2 13   ? 212.163 329.548 213.121 1.00 103.14 ? 13   ALA C CB    1 
ATOM   7824  N N     . GLN B 2 14   ? 215.438 329.704 213.046 1.00 104.44 ? 14   GLN C N     1 
ATOM   7825  C CA    . GLN B 2 14   ? 216.685 329.619 213.801 1.00 104.44 ? 14   GLN C CA    1 
ATOM   7826  C C     . GLN B 2 14   ? 217.421 330.953 213.806 1.00 104.44 ? 14   GLN C C     1 
ATOM   7827  O O     . GLN B 2 14   ? 217.948 331.376 214.842 1.00 104.44 ? 14   GLN C O     1 
ATOM   7828  C CB    . GLN B 2 14   ? 217.573 328.517 213.225 1.00 104.44 ? 14   GLN C CB    1 
ATOM   7829  N N     . ASP B 2 15   ? 217.472 331.628 212.654 1.00 105.13 ? 15   ASP C N     1 
ATOM   7830  C CA    . ASP B 2 15   ? 218.126 332.931 212.588 1.00 105.13 ? 15   ASP C CA    1 
ATOM   7831  C C     . ASP B 2 15   ? 217.408 333.953 213.461 1.00 105.13 ? 15   ASP C C     1 
ATOM   7832  O O     . ASP B 2 15   ? 218.051 334.754 214.149 1.00 105.13 ? 15   ASP C O     1 
ATOM   7833  C CB    . ASP B 2 15   ? 218.191 333.413 211.139 1.00 105.13 ? 15   ASP C CB    1 
ATOM   7834  C CG    . ASP B 2 15   ? 219.288 332.728 210.347 1.00 105.13 ? 15   ASP C CG    1 
ATOM   7835  O OD1   . ASP B 2 15   ? 220.047 331.935 210.942 1.00 105.13 ? 15   ASP C OD1   1 
ATOM   7836  O OD2   . ASP B 2 15   ? 219.390 332.983 209.128 1.00 105.13 ? 15   ASP C OD2   1 
ATOM   7837  N N     . PHE B 2 16   ? 216.073 333.942 213.442 1.00 104.41 ? 16   PHE C N     1 
ATOM   7838  C CA    . PHE B 2 16   ? 215.312 334.859 214.285 1.00 104.41 ? 16   PHE C CA    1 
ATOM   7839  C C     . PHE B 2 16   ? 215.562 334.587 215.763 1.00 104.41 ? 16   PHE C C     1 
ATOM   7840  O O     . PHE B 2 16   ? 215.714 335.522 216.557 1.00 104.41 ? 16   PHE C O     1 
ATOM   7841  C CB    . PHE B 2 16   ? 213.822 334.752 213.964 1.00 104.41 ? 16   PHE C CB    1 
ATOM   7842  N N     . TYR B 2 17   ? 215.602 333.310 216.151 1.00 103.11 ? 17   TYR C N     1 
ATOM   7843  C CA    . TYR B 2 17   ? 215.865 332.967 217.545 1.00 103.11 ? 17   TYR C CA    1 
ATOM   7844  C C     . TYR B 2 17   ? 217.267 333.391 217.964 1.00 103.11 ? 17   TYR C C     1 
ATOM   7845  O O     . TYR B 2 17   ? 217.465 333.898 219.074 1.00 103.11 ? 17   TYR C O     1 
ATOM   7846  C CB    . TYR B 2 17   ? 215.669 331.467 217.761 1.00 103.11 ? 17   TYR C CB    1 
ATOM   7847  N N     . GLU B 2 18   ? 218.255 333.190 217.089 1.00 106.81 ? 18   GLU C N     1 
ATOM   7848  C CA    . GLU B 2 18   ? 219.626 333.565 217.414 1.00 106.81 ? 18   GLU C CA    1 
ATOM   7849  C C     . GLU B 2 18   ? 219.840 335.073 217.390 1.00 106.81 ? 18   GLU C C     1 
ATOM   7850  O O     . GLU B 2 18   ? 220.780 335.561 218.026 1.00 106.81 ? 18   GLU C O     1 
ATOM   7851  C CB    . GLU B 2 18   ? 220.599 332.888 216.447 1.00 106.81 ? 18   GLU C CB    1 
ATOM   7852  N N     . ASN B 2 19   ? 218.996 335.818 216.677 1.00 110.79 ? 19   ASN C N     1 
ATOM   7853  C CA    . ASN B 2 19   ? 219.150 337.263 216.568 1.00 110.79 ? 19   ASN C CA    1 
ATOM   7854  C C     . ASN B 2 19   ? 218.189 338.043 217.453 1.00 110.79 ? 19   ASN C C     1 
ATOM   7855  O O     . ASN B 2 19   ? 218.508 339.168 217.850 1.00 110.79 ? 19   ASN C O     1 
ATOM   7856  C CB    . ASN B 2 19   ? 218.961 337.706 215.113 1.00 110.79 ? 19   ASN C CB    1 
ATOM   7857  C CG    . ASN B 2 19   ? 220.257 337.688 214.325 1.00 110.79 ? 19   ASN C CG    1 
ATOM   7858  O OD1   . ASN B 2 19   ? 220.461 338.501 213.425 1.00 110.79 ? 19   ASN C OD1   1 
ATOM   7859  N ND2   . ASN B 2 19   ? 221.140 336.755 214.662 1.00 110.79 ? 19   ASN C ND2   1 
ATOM   7860  N N     . TYR B 2 20   ? 217.026 337.480 217.773 1.00 106.46 ? 20   TYR C N     1 
ATOM   7861  C CA    . TYR B 2 20   ? 216.026 338.144 218.597 1.00 106.46 ? 20   TYR C CA    1 
ATOM   7862  C C     . TYR B 2 20   ? 215.753 337.306 219.837 1.00 106.46 ? 20   TYR C C     1 
ATOM   7863  O O     . TYR B 2 20   ? 215.564 336.089 219.739 1.00 106.46 ? 20   TYR C O     1 
ATOM   7864  C CB    . TYR B 2 20   ? 214.729 338.373 217.815 1.00 106.46 ? 20   TYR C CB    1 
ATOM   7865  N N     . GLU B 2 21   ? 215.735 337.958 220.997 1.00 104.91 ? 21   GLU C N     1 
ATOM   7866  C CA    . GLU B 2 21   ? 215.491 337.282 222.266 1.00 104.91 ? 21   GLU C CA    1 
ATOM   7867  C C     . GLU B 2 21   ? 214.117 337.661 222.798 1.00 104.91 ? 21   GLU C C     1 
ATOM   7868  O O     . GLU B 2 21   ? 213.883 338.842 223.102 1.00 104.91 ? 21   GLU C O     1 
ATOM   7869  C CB    . GLU B 2 21   ? 216.574 337.641 223.284 1.00 104.91 ? 21   GLU C CB    1 
ATOM   7870  C CG    . GLU B 2 21   ? 217.875 336.882 223.097 1.00 104.91 ? 21   GLU C CG    1 
ATOM   7871  C CD    . GLU B 2 21   ? 218.541 336.539 224.414 1.00 104.91 ? 21   GLU C CD    1 
ATOM   7872  O OE1   . GLU B 2 21   ? 218.697 337.446 225.258 1.00 104.91 ? 21   GLU C OE1   1 
ATOM   7873  O OE2   . GLU B 2 21   ? 218.911 335.362 224.604 1.00 104.91 ? 21   GLU C OE2   1 
ATOM   7874  N N     . PRO B 2 22   ? 213.181 336.719 222.912 1.00 97.02  ? 22   PRO C N     1 
ATOM   7875  C CA    . PRO B 2 22   ? 211.871 337.048 223.491 1.00 97.02  ? 22   PRO C CA    1 
ATOM   7876  C C     . PRO B 2 22   ? 212.008 337.563 224.916 1.00 97.02  ? 22   PRO C C     1 
ATOM   7877  O O     . PRO B 2 22   ? 212.860 337.115 225.687 1.00 97.02  ? 22   PRO C O     1 
ATOM   7878  C CB    . PRO B 2 22   ? 211.105 335.718 223.454 1.00 97.02  ? 22   PRO C CB    1 
ATOM   7879  C CG    . PRO B 2 22   ? 211.919 334.769 222.660 1.00 97.02  ? 22   PRO C CG    1 
ATOM   7880  C CD    . PRO B 2 22   ? 213.238 335.372 222.319 1.00 97.02  ? 22   PRO C CD    1 
ATOM   7881  N N     . LYS B 2 23   ? 211.145 338.519 225.262 1.00 90.87  ? 23   LYS C N     1 
ATOM   7882  C CA    . LYS B 2 23   ? 211.173 339.147 226.579 1.00 90.87  ? 23   LYS C CA    1 
ATOM   7883  C C     . LYS B 2 23   ? 209.767 339.267 227.152 1.00 90.87  ? 23   LYS C C     1 
ATOM   7884  O O     . LYS B 2 23   ? 208.831 338.632 226.655 1.00 90.87  ? 23   LYS C O     1 
ATOM   7885  C CB    . LYS B 2 23   ? 211.836 340.526 226.510 1.00 90.87  ? 23   LYS C CB    1 
ATOM   7886  C CG    . LYS B 2 23   ? 213.283 340.512 226.037 1.00 90.87  ? 23   LYS C CG    1 
ATOM   7887  C CD    . LYS B 2 23   ? 214.191 339.772 227.012 1.00 90.87  ? 23   LYS C CD    1 
ATOM   7888  C CE    . LYS B 2 23   ? 214.032 340.292 228.434 1.00 90.87  ? 23   LYS C CE    1 
ATOM   7889  N NZ    . LYS B 2 23   ? 214.653 339.379 229.432 1.00 90.87  ? 23   LYS C NZ    1 
ATOM   7890  N N     . GLU B 2 24   ? 209.616 340.071 228.202 1.00 86.14  ? 24   GLU C N     1 
ATOM   7891  C CA    . GLU B 2 24   ? 208.321 340.235 228.847 1.00 86.14  ? 24   GLU C CA    1 
ATOM   7892  C C     . GLU B 2 24   ? 207.311 340.851 227.885 1.00 86.14  ? 24   GLU C C     1 
ATOM   7893  O O     . GLU B 2 24   ? 207.659 341.626 226.990 1.00 86.14  ? 24   GLU C O     1 
ATOM   7894  C CB    . GLU B 2 24   ? 208.455 341.108 230.096 1.00 86.14  ? 24   GLU C CB    1 
ATOM   7895  N N     . ILE B 2 25   ? 206.040 340.487 228.077 1.00 75.49  ? 25   ILE C N     1 
ATOM   7896  C CA    . ILE B 2 25   ? 204.983 340.951 227.187 1.00 75.49  ? 25   ILE C CA    1 
ATOM   7897  C C     . ILE B 2 25   ? 204.795 342.451 227.347 1.00 75.49  ? 25   ILE C C     1 
ATOM   7898  O O     . ILE B 2 25   ? 204.714 342.971 228.468 1.00 75.49  ? 25   ILE C O     1 
ATOM   7899  C CB    . ILE B 2 25   ? 203.679 340.190 227.468 1.00 75.49  ? 25   ILE C CB    1 
ATOM   7900  C CG1   . ILE B 2 25   ? 203.939 338.682 227.501 1.00 75.49  ? 25   ILE C CG1   1 
ATOM   7901  C CG2   . ILE B 2 25   ? 202.625 340.534 226.428 1.00 75.49  ? 25   ILE C CG2   1 
ATOM   7902  C CD1   . ILE B 2 25   ? 202.695 337.852 227.732 1.00 75.49  ? 25   ILE C CD1   1 
ATOM   7903  N N     . LEU B 2 26   ? 204.723 343.158 226.217 1.00 75.59  ? 26   LEU C N     1 
ATOM   7904  C CA    . LEU B 2 26   ? 204.492 344.594 226.210 1.00 75.59  ? 26   LEU C CA    1 
ATOM   7905  C C     . LEU B 2 26   ? 203.103 344.984 225.727 1.00 75.59  ? 26   LEU C C     1 
ATOM   7906  O O     . LEU B 2 26   ? 202.671 346.111 225.987 1.00 75.59  ? 26   LEU C O     1 
ATOM   7907  C CB    . LEU B 2 26   ? 205.539 345.297 225.331 1.00 75.59  ? 26   LEU C CB    1 
ATOM   7908  C CG    . LEU B 2 26   ? 205.789 346.785 225.589 1.00 75.59  ? 26   LEU C CG    1 
ATOM   7909  C CD1   . LEU B 2 26   ? 205.875 347.069 227.082 1.00 75.59  ? 26   LEU C CD1   1 
ATOM   7910  C CD2   . LEU B 2 26   ? 207.051 347.250 224.878 1.00 75.59  ? 26   LEU C CD2   1 
ATOM   7911  N N     . GLY B 2 27   ? 202.398 344.089 225.046 1.00 72.56  ? 27   GLY C N     1 
ATOM   7912  C CA    . GLY B 2 27   ? 201.065 344.391 224.563 1.00 72.56  ? 27   GLY C CA    1 
ATOM   7913  C C     . GLY B 2 27   ? 200.372 343.138 224.083 1.00 72.56  ? 27   GLY C C     1 
ATOM   7914  O O     . GLY B 2 27   ? 201.007 342.106 223.841 1.00 72.56  ? 27   GLY C O     1 
ATOM   7915  N N     . ARG B 2 28   ? 199.052 343.244 223.948 1.00 71.15  ? 28   ARG C N     1 
ATOM   7916  C CA    . ARG B 2 28   ? 198.218 342.134 223.516 1.00 71.15  ? 28   ARG C CA    1 
ATOM   7917  C C     . ARG B 2 28   ? 197.256 342.602 222.434 1.00 71.15  ? 28   ARG C C     1 
ATOM   7918  O O     . ARG B 2 28   ? 196.843 343.764 222.406 1.00 71.15  ? 28   ARG C O     1 
ATOM   7919  C CB    . ARG B 2 28   ? 197.431 341.531 224.688 1.00 71.15  ? 28   ARG C CB    1 
ATOM   7920  N N     . GLY B 2 29   ? 196.904 341.680 221.541 1.00 82.71  ? 29   GLY C N     1 
ATOM   7921  C CA    . GLY B 2 29   ? 195.975 341.977 220.469 1.00 82.71  ? 29   GLY C CA    1 
ATOM   7922  C C     . GLY B 2 29   ? 194.863 340.955 220.360 1.00 82.71  ? 29   GLY C C     1 
ATOM   7923  O O     . GLY B 2 29   ? 194.691 340.120 221.253 1.00 82.71  ? 29   GLY C O     1 
ATOM   7924  N N     . VAL B 2 30   ? 194.093 341.017 219.271 1.00 87.61  ? 30   VAL C N     1 
ATOM   7925  C CA    . VAL B 2 30   ? 193.010 340.056 219.070 1.00 87.61  ? 30   VAL C CA    1 
ATOM   7926  C C     . VAL B 2 30   ? 193.572 338.649 218.899 1.00 87.61  ? 30   VAL C C     1 
ATOM   7927  O O     . VAL B 2 30   ? 193.054 337.680 219.468 1.00 87.61  ? 30   VAL C O     1 
ATOM   7928  C CB    . VAL B 2 30   ? 192.132 340.476 217.875 1.00 87.61  ? 30   VAL C CB    1 
ATOM   7929  C CG1   . VAL B 2 30   ? 192.984 340.761 216.643 1.00 87.61  ? 30   VAL C CG1   1 
ATOM   7930  C CG2   . VAL B 2 30   ? 191.090 339.408 217.576 1.00 87.61  ? 30   VAL C CG2   1 
ATOM   7931  N N     . SER B 2 31   ? 194.647 338.515 218.117 1.00 85.40  ? 31   SER C N     1 
ATOM   7932  C CA    . SER B 2 31   ? 195.285 337.220 217.921 1.00 85.40  ? 31   SER C CA    1 
ATOM   7933  C C     . SER B 2 31   ? 196.806 337.314 217.905 1.00 85.40  ? 31   SER C C     1 
ATOM   7934  O O     . SER B 2 31   ? 197.462 336.373 217.440 1.00 85.40  ? 31   SER C O     1 
ATOM   7935  C CB    . SER B 2 31   ? 194.794 336.568 216.622 1.00 85.40  ? 31   SER C CB    1 
ATOM   7936  O OG    . SER B 2 31   ? 195.041 337.405 215.506 1.00 85.40  ? 31   SER C OG    1 
ATOM   7937  N N     . SER B 2 32   ? 197.388 338.407 218.393 1.00 80.91  ? 32   SER C N     1 
ATOM   7938  C CA    . SER B 2 32   ? 198.827 338.609 218.353 1.00 80.91  ? 32   SER C CA    1 
ATOM   7939  C C     . SER B 2 32   ? 199.325 339.091 219.708 1.00 80.91  ? 32   SER C C     1 
ATOM   7940  O O     . SER B 2 32   ? 198.587 339.713 220.476 1.00 80.91  ? 32   SER C O     1 
ATOM   7941  C CB    . SER B 2 32   ? 199.221 339.620 217.267 1.00 80.91  ? 32   SER C CB    1 
ATOM   7942  O OG    . SER B 2 32   ? 199.176 340.946 217.764 1.00 80.91  ? 32   SER C OG    1 
ATOM   7943  N N     . VAL B 2 33   ? 200.592 338.795 219.990 1.00 71.81  ? 33   VAL C N     1 
ATOM   7944  C CA    . VAL B 2 33   ? 201.253 339.208 221.222 1.00 71.81  ? 33   VAL C CA    1 
ATOM   7945  C C     . VAL B 2 33   ? 202.525 339.961 220.851 1.00 71.81  ? 33   VAL C C     1 
ATOM   7946  O O     . VAL B 2 33   ? 203.282 339.521 219.979 1.00 71.81  ? 33   VAL C O     1 
ATOM   7947  C CB    . VAL B 2 33   ? 201.564 338.006 222.138 1.00 71.81  ? 33   VAL C CB    1 
ATOM   7948  C CG1   . VAL B 2 33   ? 202.345 336.934 221.387 1.00 71.81  ? 33   VAL C CG1   1 
ATOM   7949  C CG2   . VAL B 2 33   ? 202.322 338.458 223.377 1.00 71.81  ? 33   VAL C CG2   1 
ATOM   7950  N N     . VAL B 2 34   ? 202.745 341.106 221.495 1.00 75.23  ? 34   VAL C N     1 
ATOM   7951  C CA    . VAL B 2 34   ? 203.896 341.961 221.227 1.00 75.23  ? 34   VAL C CA    1 
ATOM   7952  C C     . VAL B 2 34   ? 204.822 341.918 222.433 1.00 75.23  ? 34   VAL C C     1 
ATOM   7953  O O     . VAL B 2 34   ? 204.398 342.197 223.561 1.00 75.23  ? 34   VAL C O     1 
ATOM   7954  C CB    . VAL B 2 34   ? 203.465 343.405 220.916 1.00 75.23  ? 34   VAL C CB    1 
ATOM   7955  C CG1   . VAL B 2 34   ? 204.659 344.225 220.450 1.00 75.23  ? 34   VAL C CG1   1 
ATOM   7956  C CG2   . VAL B 2 34   ? 202.362 343.415 219.868 1.00 75.23  ? 34   VAL C CG2   1 
ATOM   7957  N N     . ARG B 2 35   ? 206.085 341.567 222.195 1.00 78.98  ? 35   ARG C N     1 
ATOM   7958  C CA    . ARG B 2 35   ? 207.094 341.487 223.239 1.00 78.98  ? 35   ARG C CA    1 
ATOM   7959  C C     . ARG B 2 35   ? 208.359 342.199 222.782 1.00 78.98  ? 35   ARG C C     1 
ATOM   7960  O O     . ARG B 2 35   ? 208.591 342.377 221.583 1.00 78.98  ? 35   ARG C O     1 
ATOM   7961  C CB    . ARG B 2 35   ? 207.426 340.029 223.604 1.00 78.98  ? 35   ARG C CB    1 
ATOM   7962  C CG    . ARG B 2 35   ? 206.280 339.048 223.409 1.00 78.98  ? 35   ARG C CG    1 
ATOM   7963  C CD    . ARG B 2 35   ? 206.741 337.613 223.603 1.00 78.98  ? 35   ARG C CD    1 
ATOM   7964  N NE    . ARG B 2 35   ? 206.755 337.227 225.009 1.00 78.98  ? 35   ARG C NE    1 
ATOM   7965  C CZ    . ARG B 2 35   ? 205.961 336.308 225.541 1.00 78.98  ? 35   ARG C CZ    1 
ATOM   7966  N NH1   . ARG B 2 35   ? 205.073 335.655 224.810 1.00 78.98  ? 35   ARG C NH1   1 
ATOM   7967  N NH2   . ARG B 2 35   ? 206.062 336.037 226.839 1.00 78.98  ? 35   ARG C NH2   1 
ATOM   7968  N N     . ARG B 2 36   ? 209.169 342.615 223.750 1.00 94.32  ? 36   ARG C N     1 
ATOM   7969  C CA    . ARG B 2 36   ? 210.437 343.259 223.440 1.00 94.32  ? 36   ARG C CA    1 
ATOM   7970  C C     . ARG B 2 36   ? 211.464 342.231 222.977 1.00 94.32  ? 36   ARG C C     1 
ATOM   7971  O O     . ARG B 2 36   ? 211.398 341.050 223.327 1.00 94.32  ? 36   ARG C O     1 
ATOM   7972  C CB    . ARG B 2 36   ? 210.965 344.015 224.659 1.00 94.32  ? 36   ARG C CB    1 
ATOM   7973  N N     . CYS B 2 37   ? 212.420 342.694 222.174 1.00 109.07 ? 37   CYS C N     1 
ATOM   7974  C CA    . CYS B 2 37   ? 213.493 341.850 221.669 1.00 109.07 ? 37   CYS C CA    1 
ATOM   7975  C C     . CYS B 2 37   ? 214.807 342.617 221.697 1.00 109.07 ? 37   CYS C C     1 
ATOM   7976  O O     . CYS B 2 37   ? 214.827 343.850 221.664 1.00 109.07 ? 37   CYS C O     1 
ATOM   7977  C CB    . CYS B 2 37   ? 213.208 341.362 220.242 1.00 109.07 ? 37   CYS C CB    1 
ATOM   7978  S SG    . CYS B 2 37   ? 213.075 342.677 219.011 1.00 109.07 ? 37   CYS C SG    1 
ATOM   7979  N N     . ILE B 2 38   ? 215.907 341.872 221.760 1.00 119.99 ? 38   ILE C N     1 
ATOM   7980  C CA    . ILE B 2 38   ? 217.251 342.436 221.773 1.00 119.99 ? 38   ILE C CA    1 
ATOM   7981  C C     . ILE B 2 38   ? 218.031 341.847 220.607 1.00 119.99 ? 38   ILE C C     1 
ATOM   7982  O O     . ILE B 2 38   ? 218.081 340.623 220.442 1.00 119.99 ? 38   ILE C O     1 
ATOM   7983  C CB    . ILE B 2 38   ? 217.971 342.163 223.107 1.00 119.99 ? 38   ILE C CB    1 
ATOM   7984  C CG1   . ILE B 2 38   ? 217.180 342.758 224.274 1.00 119.99 ? 38   ILE C CG1   1 
ATOM   7985  C CG2   . ILE B 2 38   ? 219.385 342.724 223.076 1.00 119.99 ? 38   ILE C CG2   1 
ATOM   7986  C CD1   . ILE B 2 38   ? 216.818 341.751 225.341 1.00 119.99 ? 38   ILE C CD1   1 
ATOM   7987  N N     . HIS B 2 39   ? 218.637 342.718 219.803 1.00 126.55 ? 39   HIS C N     1 
ATOM   7988  C CA    . HIS B 2 39   ? 219.468 342.300 218.679 1.00 126.55 ? 39   HIS C CA    1 
ATOM   7989  C C     . HIS B 2 39   ? 220.885 342.074 219.195 1.00 126.55 ? 39   HIS C C     1 
ATOM   7990  O O     . HIS B 2 39   ? 221.599 343.033 219.503 1.00 126.55 ? 39   HIS C O     1 
ATOM   7991  C CB    . HIS B 2 39   ? 219.441 343.350 217.571 1.00 126.55 ? 39   HIS C CB    1 
ATOM   7992  C CG    . HIS B 2 39   ? 219.767 342.807 216.215 1.00 126.55 ? 39   HIS C CG    1 
ATOM   7993  N ND1   . HIS B 2 39   ? 220.124 341.493 216.005 1.00 126.55 ? 39   HIS C ND1   1 
ATOM   7994  C CD2   . HIS B 2 39   ? 219.790 343.402 214.999 1.00 126.55 ? 39   HIS C CD2   1 
ATOM   7995  C CE1   . HIS B 2 39   ? 220.353 341.302 214.718 1.00 126.55 ? 39   HIS C CE1   1 
ATOM   7996  N NE2   . HIS B 2 39   ? 220.157 342.445 214.085 1.00 126.55 ? 39   HIS C NE2   1 
ATOM   7997  N N     . LYS B 2 40   ? 221.291 340.806 219.282 1.00 125.14 ? 40   LYS C N     1 
ATOM   7998  C CA    . LYS B 2 40   ? 222.569 340.471 219.912 1.00 125.14 ? 40   LYS C CA    1 
ATOM   7999  C C     . LYS B 2 40   ? 223.769 341.144 219.254 1.00 125.14 ? 40   LYS C C     1 
ATOM   8000  O O     . LYS B 2 40   ? 224.632 341.658 219.987 1.00 125.14 ? 40   LYS C O     1 
ATOM   8001  C CB    . LYS B 2 40   ? 222.736 338.947 219.953 1.00 125.14 ? 40   LYS C CB    1 
ATOM   8002  C CG    . LYS B 2 40   ? 221.432 338.174 220.094 1.00 125.14 ? 40   LYS C CG    1 
ATOM   8003  C CD    . LYS B 2 40   ? 220.787 338.401 221.456 1.00 125.14 ? 40   LYS C CD    1 
ATOM   8004  C CE    . LYS B 2 40   ? 221.781 338.189 222.589 1.00 125.14 ? 40   LYS C CE    1 
ATOM   8005  N NZ    . LYS B 2 40   ? 221.137 338.313 223.925 1.00 125.14 ? 40   LYS C NZ    1 
ATOM   8006  N N     . PRO B 2 41   ? 223.910 341.174 217.922 1.00 127.73 ? 41   PRO C N     1 
ATOM   8007  C CA    . PRO B 2 41   ? 225.057 341.896 217.342 1.00 127.73 ? 41   PRO C CA    1 
ATOM   8008  C C     . PRO B 2 41   ? 225.083 343.377 217.680 1.00 127.73 ? 41   PRO C C     1 
ATOM   8009  O O     . PRO B 2 41   ? 226.167 343.971 217.732 1.00 127.73 ? 41   PRO C O     1 
ATOM   8010  C CB    . PRO B 2 41   ? 224.888 341.667 215.833 1.00 127.73 ? 41   PRO C CB    1 
ATOM   8011  C CG    . PRO B 2 41   ? 224.107 340.415 215.726 1.00 127.73 ? 41   PRO C CG    1 
ATOM   8012  C CD    . PRO B 2 41   ? 223.165 340.427 216.890 1.00 127.73 ? 41   PRO C CD    1 
ATOM   8013  N N     . THR B 2 42   ? 223.924 343.993 217.912 1.00 125.05 ? 42   THR C N     1 
ATOM   8014  C CA    . THR B 2 42   ? 223.838 345.426 218.152 1.00 125.05 ? 42   THR C CA    1 
ATOM   8015  C C     . THR B 2 42   ? 223.471 345.775 219.590 1.00 125.05 ? 42   THR C C     1 
ATOM   8016  O O     . THR B 2 42   ? 223.724 346.908 220.018 1.00 125.05 ? 42   THR C O     1 
ATOM   8017  C CB    . THR B 2 42   ? 222.814 346.052 217.187 1.00 125.05 ? 42   THR C CB    1 
ATOM   8018  O OG1   . THR B 2 42   ? 223.103 345.626 215.850 1.00 125.05 ? 42   THR C OG1   1 
ATOM   8019  C CG2   . THR B 2 42   ? 222.874 347.575 217.223 1.00 125.05 ? 42   THR C CG2   1 
ATOM   8020  N N     . SER B 2 43   ? 222.922 344.827 220.354 1.00 129.11 ? 43   SER C N     1 
ATOM   8021  C CA    . SER B 2 43   ? 222.421 345.085 221.707 1.00 129.11 ? 43   SER C CA    1 
ATOM   8022  C C     . SER B 2 43   ? 221.358 346.181 221.696 1.00 129.11 ? 43   SER C C     1 
ATOM   8023  O O     . SER B 2 43   ? 221.316 347.044 222.576 1.00 129.11 ? 43   SER C O     1 
ATOM   8024  C CB    . SER B 2 43   ? 223.558 345.432 222.672 1.00 129.11 ? 43   SER C CB    1 
ATOM   8025  O OG    . SER B 2 43   ? 223.156 345.253 224.019 1.00 129.11 ? 43   SER C OG    1 
ATOM   8026  N N     . GLN B 2 44   ? 220.491 346.144 220.688 1.00 120.88 ? 44   GLN C N     1 
ATOM   8027  C CA    . GLN B 2 44   ? 219.425 347.121 220.551 1.00 120.88 ? 44   GLN C CA    1 
ATOM   8028  C C     . GLN B 2 44   ? 218.242 346.753 221.445 1.00 120.88 ? 44   GLN C C     1 
ATOM   8029  O O     . GLN B 2 44   ? 218.217 345.707 222.098 1.00 120.88 ? 44   GLN C O     1 
ATOM   8030  C CB    . GLN B 2 44   ? 218.980 347.227 219.094 1.00 120.88 ? 44   GLN C CB    1 
ATOM   8031  N N     . GLU B 2 45   ? 217.249 347.638 221.467 1.00 106.70 ? 45   GLU C N     1 
ATOM   8032  C CA    . GLU B 2 45   ? 216.053 347.481 222.284 1.00 106.70 ? 45   GLU C CA    1 
ATOM   8033  C C     . GLU B 2 45   ? 214.794 347.526 221.425 1.00 106.70 ? 45   GLU C C     1 
ATOM   8034  O O     . GLU B 2 45   ? 213.829 348.223 221.742 1.00 106.70 ? 45   GLU C O     1 
ATOM   8035  C CB    . GLU B 2 45   ? 215.998 348.547 223.376 1.00 106.70 ? 45   GLU C CB    1 
ATOM   8036  N N     . TYR B 2 46   ? 214.794 346.784 220.320 1.00 98.58  ? 46   TYR C N     1 
ATOM   8037  C CA    . TYR B 2 46   ? 213.651 346.763 219.419 1.00 98.58  ? 46   TYR C CA    1 
ATOM   8038  C C     . TYR B 2 46   ? 212.510 345.943 220.024 1.00 98.58  ? 46   TYR C C     1 
ATOM   8039  O O     . TYR B 2 46   ? 212.576 345.466 221.161 1.00 98.58  ? 46   TYR C O     1 
ATOM   8040  C CB    . TYR B 2 46   ? 214.061 346.203 218.059 1.00 98.58  ? 46   TYR C CB    1 
ATOM   8041  C CG    . TYR B 2 46   ? 214.585 347.244 217.094 1.00 98.58  ? 46   TYR C CG    1 
ATOM   8042  C CD1   . TYR B 2 46   ? 214.533 348.597 217.404 1.00 98.58  ? 46   TYR C CD1   1 
ATOM   8043  C CD2   . TYR B 2 46   ? 215.132 346.872 215.873 1.00 98.58  ? 46   TYR C CD2   1 
ATOM   8044  C CE1   . TYR B 2 46   ? 215.012 349.550 216.524 1.00 98.58  ? 46   TYR C CE1   1 
ATOM   8045  C CE2   . TYR B 2 46   ? 215.613 347.818 214.987 1.00 98.58  ? 46   TYR C CE2   1 
ATOM   8046  C CZ    . TYR B 2 46   ? 215.550 349.155 215.318 1.00 98.58  ? 46   TYR C CZ    1 
ATOM   8047  O OH    . TYR B 2 46   ? 216.028 350.100 214.439 1.00 98.58  ? 46   TYR C OH    1 
ATOM   8048  N N     . ALA B 2 47   ? 211.441 345.782 219.246 1.00 92.66  ? 47   ALA C N     1 
ATOM   8049  C CA    . ALA B 2 47   ? 210.277 345.007 219.648 1.00 92.66  ? 47   ALA C CA    1 
ATOM   8050  C C     . ALA B 2 47   ? 209.908 344.027 218.543 1.00 92.66  ? 47   ALA C C     1 
ATOM   8051  O O     . ALA B 2 47   ? 210.094 344.316 217.357 1.00 92.66  ? 47   ALA C O     1 
ATOM   8052  C CB    . ALA B 2 47   ? 209.083 345.915 219.960 1.00 92.66  ? 47   ALA C CB    1 
ATOM   8053  N N     . VAL B 2 48   ? 209.384 342.869 218.936 1.00 86.48  ? 48   VAL C N     1 
ATOM   8054  C CA    . VAL B 2 48   ? 208.983 341.823 218.003 1.00 86.48  ? 48   VAL C CA    1 
ATOM   8055  C C     . VAL B 2 48   ? 207.492 341.563 218.176 1.00 86.48  ? 48   VAL C C     1 
ATOM   8056  O O     . VAL B 2 48   ? 207.010 341.395 219.302 1.00 86.48  ? 48   VAL C O     1 
ATOM   8057  C CB    . VAL B 2 48   ? 209.800 340.530 218.205 1.00 86.48  ? 48   VAL C CB    1 
ATOM   8058  C CG1   . VAL B 2 48   ? 209.832 340.127 219.672 1.00 86.48  ? 48   VAL C CG1   1 
ATOM   8059  C CG2   . VAL B 2 48   ? 209.241 339.404 217.346 1.00 86.48  ? 48   VAL C CG2   1 
ATOM   8060  N N     . LYS B 2 49   ? 206.765 341.549 217.062 1.00 80.82  ? 49   LYS C N     1 
ATOM   8061  C CA    . LYS B 2 49   ? 205.337 341.261 217.055 1.00 80.82  ? 49   LYS C CA    1 
ATOM   8062  C C     . LYS B 2 49   ? 205.111 339.856 216.514 1.00 80.82  ? 49   LYS C C     1 
ATOM   8063  O O     . LYS B 2 49   ? 205.561 339.531 215.410 1.00 80.82  ? 49   LYS C O     1 
ATOM   8064  C CB    . LYS B 2 49   ? 204.578 342.286 216.211 1.00 80.82  ? 49   LYS C CB    1 
ATOM   8065  C CG    . LYS B 2 49   ? 203.194 341.834 215.771 1.00 80.82  ? 49   LYS C CG    1 
ATOM   8066  C CD    . LYS B 2 49   ? 202.418 342.978 215.137 1.00 80.82  ? 49   LYS C CD    1 
ATOM   8067  C CE    . LYS B 2 49   ? 200.999 342.559 214.787 1.00 80.82  ? 49   LYS C CE    1 
ATOM   8068  N NZ    . LYS B 2 49   ? 200.100 342.601 215.973 1.00 80.82  ? 49   LYS C NZ    1 
ATOM   8069  N N     . VAL B 2 50   ? 204.417 339.029 217.290 1.00 76.49  ? 50   VAL C N     1 
ATOM   8070  C CA    . VAL B 2 50   ? 204.165 337.634 216.942 1.00 76.49  ? 50   VAL C CA    1 
ATOM   8071  C C     . VAL B 2 50   ? 202.660 337.437 216.830 1.00 76.49  ? 50   VAL C C     1 
ATOM   8072  O O     . VAL B 2 50   ? 201.914 337.743 217.768 1.00 76.49  ? 50   VAL C O     1 
ATOM   8073  C CB    . VAL B 2 50   ? 204.771 336.674 217.977 1.00 76.49  ? 50   VAL C CB    1 
ATOM   8074  C CG1   . VAL B 2 50   ? 204.550 335.233 217.553 1.00 76.49  ? 50   VAL C CG1   1 
ATOM   8075  C CG2   . VAL B 2 50   ? 206.255 336.958 218.159 1.00 76.49  ? 50   VAL C CG2   1 
ATOM   8076  N N     . ILE B 2 51   ? 202.215 336.924 215.685 1.00 80.47  ? 51   ILE C N     1 
ATOM   8077  C CA    . ILE B 2 51   ? 200.804 336.662 215.424 1.00 80.47  ? 51   ILE C CA    1 
ATOM   8078  C C     . ILE B 2 51   ? 200.664 335.200 215.020 1.00 80.47  ? 51   ILE C C     1 
ATOM   8079  O O     . ILE B 2 51   ? 201.383 334.724 214.133 1.00 80.47  ? 51   ILE C O     1 
ATOM   8080  C CB    . ILE B 2 51   ? 200.240 337.595 214.340 1.00 80.47  ? 51   ILE C CB    1 
ATOM   8081  C CG1   . ILE B 2 51   ? 198.905 337.064 213.811 1.00 80.47  ? 51   ILE C CG1   1 
ATOM   8082  C CG2   . ILE B 2 51   ? 201.245 337.775 213.208 1.00 80.47  ? 51   ILE C CG2   1 
ATOM   8083  C CD1   . ILE B 2 51   ? 198.242 337.976 212.802 1.00 80.47  ? 51   ILE C CD1   1 
ATOM   8084  N N     . ASP B 2 52   ? 199.743 334.493 215.670 1.00 91.91  ? 52   ASP C N     1 
ATOM   8085  C CA    . ASP B 2 52   ? 199.520 333.089 215.359 1.00 91.91  ? 52   ASP C CA    1 
ATOM   8086  C C     . ASP B 2 52   ? 198.780 332.939 214.034 1.00 91.91  ? 52   ASP C C     1 
ATOM   8087  O O     . ASP B 2 52   ? 198.039 333.827 213.604 1.00 91.91  ? 52   ASP C O     1 
ATOM   8088  C CB    . ASP B 2 52   ? 198.730 332.411 216.479 1.00 91.91  ? 52   ASP C CB    1 
ATOM   8089  C CG    . ASP B 2 52   ? 199.409 332.537 217.829 1.00 91.91  ? 52   ASP C CG    1 
ATOM   8090  O OD1   . ASP B 2 52   ? 199.230 333.580 218.492 1.00 91.91  ? 52   ASP C OD1   1 
ATOM   8091  O OD2   . ASP B 2 52   ? 200.121 331.591 218.227 1.00 91.91  ? 52   ASP C OD2   1 
ATOM   8092  N N     . VAL B 2 53   ? 198.989 331.794 213.386 1.00 91.74  ? 53   VAL C N     1 
ATOM   8093  C CA    . VAL B 2 53   ? 198.362 331.508 212.101 1.00 91.74  ? 53   VAL C CA    1 
ATOM   8094  C C     . VAL B 2 53   ? 197.124 330.649 212.319 1.00 91.74  ? 53   VAL C C     1 
ATOM   8095  O O     . VAL B 2 53   ? 196.008 331.047 211.967 1.00 91.74  ? 53   VAL C O     1 
ATOM   8096  C CB    . VAL B 2 53   ? 199.346 330.815 211.142 1.00 91.74  ? 53   VAL C CB    1 
ATOM   8097  C CG1   . VAL B 2 53   ? 198.869 330.948 209.703 1.00 91.74  ? 53   VAL C CG1   1 
ATOM   8098  C CG2   . VAL B 2 53   ? 200.737 331.395 211.307 1.00 91.74  ? 53   VAL C CG2   1 
ATOM   8099  N N     . THR B 2 54   ? 197.315 329.465 212.902 1.00 95.43  ? 54   THR C N     1 
ATOM   8100  C CA    . THR B 2 54   ? 196.203 328.553 213.132 1.00 95.43  ? 54   THR C CA    1 
ATOM   8101  C C     . THR B 2 54   ? 195.350 328.954 214.327 1.00 95.43  ? 54   THR C C     1 
ATOM   8102  O O     . THR B 2 54   ? 194.222 328.465 214.456 1.00 95.43  ? 54   THR C O     1 
ATOM   8103  C CB    . THR B 2 54   ? 196.722 327.126 213.331 1.00 95.43  ? 54   THR C CB    1 
ATOM   8104  O OG1   . THR B 2 54   ? 195.657 326.289 213.798 1.00 95.43  ? 54   THR C OG1   1 
ATOM   8105  C CG2   . THR B 2 54   ? 197.856 327.109 214.345 1.00 95.43  ? 54   THR C CG2   1 
ATOM   8106  N N     . GLY B 2 55   ? 195.856 329.827 215.194 1.00 91.34  ? 55   GLY C N     1 
ATOM   8107  C CA    . GLY B 2 55   ? 195.088 330.287 216.341 1.00 91.34  ? 55   GLY C CA    1 
ATOM   8108  C C     . GLY B 2 55   ? 194.633 329.177 217.264 1.00 91.34  ? 55   GLY C C     1 
ATOM   8109  O O     . GLY B 2 55   ? 193.494 329.202 217.746 1.00 91.34  ? 55   GLY C O     1 
ATOM   8110  N N     . GLY B 2 56   ? 195.500 328.201 217.522 1.00 88.41  ? 56   GLY C N     1 
ATOM   8111  C CA    . GLY B 2 56   ? 195.113 327.073 218.343 1.00 88.41  ? 56   GLY C CA    1 
ATOM   8112  C C     . GLY B 2 56   ? 194.179 326.096 217.670 1.00 88.41  ? 56   GLY C C     1 
ATOM   8113  O O     . GLY B 2 56   ? 193.486 325.342 218.357 1.00 88.41  ? 56   GLY C O     1 
ATOM   8114  N N     . GLY B 2 57   ? 194.143 326.083 216.341 1.00 95.40  ? 57   GLY C N     1 
ATOM   8115  C CA    . GLY B 2 57   ? 193.233 325.203 215.623 1.00 95.40  ? 57   GLY C CA    1 
ATOM   8116  C C     . GLY B 2 57   ? 191.773 325.531 215.844 1.00 95.40  ? 57   GLY C C     1 
ATOM   8117  O O     . GLY B 2 57   ? 190.949 324.620 215.993 1.00 95.40  ? 57   GLY C O     1 
ATOM   8118  N N     . SER B 2 58   ? 191.432 326.817 215.869 1.00 104.22 ? 58   SER C N     1 
ATOM   8119  C CA    . SER B 2 58   ? 190.072 327.261 216.139 1.00 104.22 ? 58   SER C CA    1 
ATOM   8120  C C     . SER B 2 58   ? 189.288 327.604 214.879 1.00 104.22 ? 58   SER C C     1 
ATOM   8121  O O     . SER B 2 58   ? 188.135 328.033 214.986 1.00 104.22 ? 58   SER C O     1 
ATOM   8122  C CB    . SER B 2 58   ? 190.092 328.473 217.076 1.00 104.22 ? 58   SER C CB    1 
ATOM   8123  O OG    . SER B 2 58   ? 188.780 328.948 217.324 1.00 104.22 ? 58   SER C OG    1 
ATOM   8124  N N     . PHE B 2 59   ? 189.871 327.428 213.695 1.00 108.66 ? 59   PHE C N     1 
ATOM   8125  C CA    . PHE B 2 59   ? 189.174 327.750 212.459 1.00 108.66 ? 59   PHE C CA    1 
ATOM   8126  C C     . PHE B 2 59   ? 189.757 326.932 211.315 1.00 108.66 ? 59   PHE C C     1 
ATOM   8127  O O     . PHE B 2 59   ? 190.802 326.291 211.445 1.00 108.66 ? 59   PHE C O     1 
ATOM   8128  C CB    . PHE B 2 59   ? 189.245 329.250 212.144 1.00 108.66 ? 59   PHE C CB    1 
ATOM   8129  C CG    . PHE B 2 59   ? 190.517 329.908 212.594 1.00 108.66 ? 59   PHE C CG    1 
ATOM   8130  C CD1   . PHE B 2 59   ? 191.698 329.714 211.896 1.00 108.66 ? 59   PHE C CD1   1 
ATOM   8131  C CD2   . PHE B 2 59   ? 190.531 330.727 213.711 1.00 108.66 ? 59   PHE C CD2   1 
ATOM   8132  C CE1   . PHE B 2 59   ? 192.869 330.323 212.306 1.00 108.66 ? 59   PHE C CE1   1 
ATOM   8133  C CE2   . PHE B 2 59   ? 191.699 331.337 214.126 1.00 108.66 ? 59   PHE C CE2   1 
ATOM   8134  C CZ    . PHE B 2 59   ? 192.870 331.135 213.422 1.00 108.66 ? 59   PHE C CZ    1 
ATOM   8135  N N     . SER B 2 60   ? 189.054 326.967 210.184 1.00 114.90 ? 60   SER C N     1 
ATOM   8136  C CA    . SER B 2 60   ? 189.451 326.239 208.992 1.00 114.90 ? 60   SER C CA    1 
ATOM   8137  C C     . SER B 2 60   ? 190.690 326.880 208.369 1.00 114.90 ? 60   SER C C     1 
ATOM   8138  O O     . SER B 2 60   ? 191.007 328.039 208.644 1.00 114.90 ? 60   SER C O     1 
ATOM   8139  C CB    . SER B 2 60   ? 188.293 326.205 207.996 1.00 114.90 ? 60   SER C CB    1 
ATOM   8140  O OG    . SER B 2 60   ? 188.235 327.403 207.242 1.00 114.90 ? 60   SER C OG    1 
ATOM   8141  N N     . PRO B 2 61   ? 191.419 326.141 207.527 1.00 115.17 ? 61   PRO C N     1 
ATOM   8142  C CA    . PRO B 2 61   ? 192.606 326.726 206.878 1.00 115.17 ? 61   PRO C CA    1 
ATOM   8143  C C     . PRO B 2 61   ? 192.296 327.909 205.976 1.00 115.17 ? 61   PRO C C     1 
ATOM   8144  O O     . PRO B 2 61   ? 193.219 328.660 205.634 1.00 115.17 ? 61   PRO C O     1 
ATOM   8145  C CB    . PRO B 2 61   ? 193.189 325.550 206.079 1.00 115.17 ? 61   PRO C CB    1 
ATOM   8146  C CG    . PRO B 2 61   ? 192.071 324.562 205.962 1.00 115.17 ? 61   PRO C CG    1 
ATOM   8147  C CD    . PRO B 2 61   ? 191.282 324.707 207.222 1.00 115.17 ? 61   PRO C CD    1 
ATOM   8148  N N     . GLU B 2 62   ? 191.037 328.093 205.566 1.00 113.18 ? 62   GLU C N     1 
ATOM   8149  C CA    . GLU B 2 62   ? 190.682 329.274 204.785 1.00 113.18 ? 62   GLU C CA    1 
ATOM   8150  C C     . GLU B 2 62   ? 190.955 330.551 205.571 1.00 113.18 ? 62   GLU C C     1 
ATOM   8151  O O     . GLU B 2 62   ? 191.485 331.528 205.025 1.00 113.18 ? 62   GLU C O     1 
ATOM   8152  C CB    . GLU B 2 62   ? 189.214 329.205 204.362 1.00 113.18 ? 62   GLU C CB    1 
ATOM   8153  C CG    . GLU B 2 62   ? 188.723 327.800 204.049 1.00 113.18 ? 62   GLU C CG    1 
ATOM   8154  C CD    . GLU B 2 62   ? 189.141 327.330 202.670 1.00 113.18 ? 62   GLU C CD    1 
ATOM   8155  O OE1   . GLU B 2 62   ? 189.101 328.146 201.725 1.00 113.18 ? 62   GLU C OE1   1 
ATOM   8156  O OE2   . GLU B 2 62   ? 189.510 326.145 202.531 1.00 113.18 ? 62   GLU C OE2   1 
ATOM   8157  N N     . GLU B 2 63   ? 190.609 330.557 206.860 1.00 115.30 ? 63   GLU C N     1 
ATOM   8158  C CA    . GLU B 2 63   ? 190.954 331.691 207.709 1.00 115.30 ? 63   GLU C CA    1 
ATOM   8159  C C     . GLU B 2 63   ? 192.464 331.856 207.811 1.00 115.30 ? 63   GLU C C     1 
ATOM   8160  O O     . GLU B 2 63   ? 192.970 332.982 207.878 1.00 115.30 ? 63   GLU C O     1 
ATOM   8161  C CB    . GLU B 2 63   ? 190.336 331.516 209.097 1.00 115.30 ? 63   GLU C CB    1 
ATOM   8162  C CG    . GLU B 2 63   ? 188.867 331.897 209.178 1.00 115.30 ? 63   GLU C CG    1 
ATOM   8163  C CD    . GLU B 2 63   ? 187.953 330.817 208.632 1.00 115.30 ? 63   GLU C CD    1 
ATOM   8164  O OE1   . GLU B 2 63   ? 188.098 329.648 209.046 1.00 115.30 ? 63   GLU C OE1   1 
ATOM   8165  O OE2   . GLU B 2 63   ? 187.089 331.138 207.789 1.00 115.30 ? 63   GLU C OE2   1 
ATOM   8166  N N     . VAL B 2 64   ? 193.203 330.743 207.814 1.00 109.16 ? 64   VAL C N     1 
ATOM   8167  C CA    . VAL B 2 64   ? 194.659 330.813 207.894 1.00 109.16 ? 64   VAL C CA    1 
ATOM   8168  C C     . VAL B 2 64   ? 195.235 331.508 206.665 1.00 109.16 ? 64   VAL C C     1 
ATOM   8169  O O     . VAL B 2 64   ? 196.094 332.392 206.780 1.00 109.16 ? 64   VAL C O     1 
ATOM   8170  C CB    . VAL B 2 64   ? 195.254 329.405 208.078 1.00 109.16 ? 64   VAL C CB    1 
ATOM   8171  N N     . ARG B 2 65   ? 194.772 331.128 205.470 1.00 106.80 ? 65   ARG C N     1 
ATOM   8172  C CA    . ARG B 2 65   ? 195.303 331.760 204.265 1.00 106.80 ? 65   ARG C CA    1 
ATOM   8173  C C     . ARG B 2 65   ? 194.832 333.206 204.147 1.00 106.80 ? 65   ARG C C     1 
ATOM   8174  O O     . ARG B 2 65   ? 195.567 334.059 203.637 1.00 106.80 ? 65   ARG C O     1 
ATOM   8175  C CB    . ARG B 2 65   ? 194.927 330.965 203.012 1.00 106.80 ? 65   ARG C CB    1 
ATOM   8176  C CG    . ARG B 2 65   ? 193.546 330.355 203.023 1.00 106.80 ? 65   ARG C CG    1 
ATOM   8177  C CD    . ARG B 2 65   ? 193.103 329.960 201.621 1.00 106.80 ? 65   ARG C CD    1 
ATOM   8178  N NE    . ARG B 2 65   ? 192.855 331.119 200.771 1.00 106.80 ? 65   ARG C NE    1 
ATOM   8179  C CZ    . ARG B 2 65   ? 191.811 331.928 200.887 1.00 106.80 ? 65   ARG C CZ    1 
ATOM   8180  N NH1   . ARG B 2 65   ? 190.878 331.729 201.804 1.00 106.80 ? 65   ARG C NH1   1 
ATOM   8181  N NH2   . ARG B 2 65   ? 191.697 332.962 200.058 1.00 106.80 ? 65   ARG C NH2   1 
ATOM   8182  N N     . GLU B 2 66   ? 193.618 333.506 204.619 1.00 105.49 ? 66   GLU C N     1 
ATOM   8183  C CA    . GLU B 2 66   ? 193.171 334.897 204.641 1.00 105.49 ? 66   GLU C CA    1 
ATOM   8184  C C     . GLU B 2 66   ? 194.053 335.743 205.554 1.00 105.49 ? 66   GLU C C     1 
ATOM   8185  O O     . GLU B 2 66   ? 194.437 336.866 205.199 1.00 105.49 ? 66   GLU C O     1 
ATOM   8186  C CB    . GLU B 2 66   ? 191.709 334.972 205.084 1.00 105.49 ? 66   GLU C CB    1 
ATOM   8187  C CG    . GLU B 2 66   ? 190.898 336.063 204.397 1.00 105.49 ? 66   GLU C CG    1 
ATOM   8188  C CD    . GLU B 2 66   ? 190.368 335.644 203.035 1.00 105.49 ? 66   GLU C CD    1 
ATOM   8189  O OE1   . GLU B 2 66   ? 190.919 334.696 202.437 1.00 105.49 ? 66   GLU C OE1   1 
ATOM   8190  O OE2   . GLU B 2 66   ? 189.395 336.268 202.562 1.00 105.49 ? 66   GLU C OE2   1 
ATOM   8191  N N     . LEU B 2 67   ? 194.393 335.214 206.733 1.00 100.77 ? 67   LEU C N     1 
ATOM   8192  C CA    . LEU B 2 67   ? 195.290 335.926 207.636 1.00 100.77 ? 67   LEU C CA    1 
ATOM   8193  C C     . LEU B 2 67   ? 196.670 336.098 207.017 1.00 100.77 ? 67   LEU C C     1 
ATOM   8194  O O     . LEU B 2 67   ? 197.290 337.159 207.153 1.00 100.77 ? 67   LEU C O     1 
ATOM   8195  C CB    . LEU B 2 67   ? 195.387 335.185 208.970 1.00 100.77 ? 67   LEU C CB    1 
ATOM   8196  C CG    . LEU B 2 67   ? 194.198 335.326 209.923 1.00 100.77 ? 67   LEU C CG    1 
ATOM   8197  C CD1   . LEU B 2 67   ? 194.572 334.860 211.321 1.00 100.77 ? 67   LEU C CD1   1 
ATOM   8198  C CD2   . LEU B 2 67   ? 193.693 336.761 209.950 1.00 100.77 ? 67   LEU C CD2   1 
ATOM   8199  N N     . ARG B 2 68   ? 197.171 335.062 206.339 1.00 95.04  ? 68   ARG C N     1 
ATOM   8200  C CA    . ARG B 2 68   ? 198.469 335.170 205.680 1.00 95.04  ? 68   ARG C CA    1 
ATOM   8201  C C     . ARG B 2 68   ? 198.450 336.246 204.601 1.00 95.04  ? 68   ARG C C     1 
ATOM   8202  O O     . ARG B 2 68   ? 199.411 337.011 204.457 1.00 95.04  ? 68   ARG C O     1 
ATOM   8203  C CB    . ARG B 2 68   ? 198.871 333.820 205.087 1.00 95.04  ? 68   ARG C CB    1 
ATOM   8204  N N     . GLU B 2 69   ? 197.360 336.318 203.833 1.00 93.51  ? 69   GLU C N     1 
ATOM   8205  C CA    . GLU B 2 69   ? 197.224 337.370 202.832 1.00 93.51  ? 69   GLU C CA    1 
ATOM   8206  C C     . GLU B 2 69   ? 197.198 338.747 203.483 1.00 93.51  ? 69   GLU C C     1 
ATOM   8207  O O     . GLU B 2 69   ? 197.812 339.695 202.976 1.00 93.51  ? 69   GLU C O     1 
ATOM   8208  C CB    . GLU B 2 69   ? 195.961 337.145 202.000 1.00 93.51  ? 69   GLU C CB    1 
ATOM   8209  N N     . ALA B 2 70   ? 196.491 338.876 204.608 1.00 88.85  ? 70   ALA C N     1 
ATOM   8210  C CA    . ALA B 2 70   ? 196.458 340.154 205.313 1.00 88.85  ? 70   ALA C CA    1 
ATOM   8211  C C     . ALA B 2 70   ? 197.851 340.568 205.776 1.00 88.85  ? 70   ALA C C     1 
ATOM   8212  O O     . ALA B 2 70   ? 198.251 341.727 205.609 1.00 88.85  ? 70   ALA C O     1 
ATOM   8213  C CB    . ALA B 2 70   ? 195.498 340.074 206.499 1.00 88.85  ? 70   ALA C CB    1 
ATOM   8214  N N     . THR B 2 71   ? 198.609 339.630 206.353 1.00 87.78  ? 71   THR C N     1 
ATOM   8215  C CA    . THR B 2 71   ? 199.958 339.956 206.810 1.00 87.78  ? 71   THR C CA    1 
ATOM   8216  C C     . THR B 2 71   ? 200.879 340.305 205.647 1.00 87.78  ? 71   THR C C     1 
ATOM   8217  O O     . THR B 2 71   ? 201.713 341.210 205.764 1.00 87.78  ? 71   THR C O     1 
ATOM   8218  C CB    . THR B 2 71   ? 200.555 338.810 207.631 1.00 87.78  ? 71   THR C CB    1 
ATOM   8219  O OG1   . THR B 2 71   ? 200.947 337.740 206.761 1.00 87.78  ? 71   THR C OG1   1 
ATOM   8220  C CG2   . THR B 2 71   ? 199.587 338.320 208.696 1.00 87.78  ? 71   THR C CG2   1 
ATOM   8221  N N     . LEU B 2 72   ? 200.765 339.591 204.522 1.00 90.07  ? 72   LEU C N     1 
ATOM   8222  C CA    . LEU B 2 72   ? 201.625 339.913 203.386 1.00 90.07  ? 72   LEU C CA    1 
ATOM   8223  C C     . LEU B 2 72   ? 201.283 341.284 202.812 1.00 90.07  ? 72   LEU C C     1 
ATOM   8224  O O     . LEU B 2 72   ? 202.181 342.047 202.436 1.00 90.07  ? 72   LEU C O     1 
ATOM   8225  C CB    . LEU B 2 72   ? 201.545 338.823 202.311 1.00 90.07  ? 72   LEU C CB    1 
ATOM   8226  C CG    . LEU B 2 72   ? 200.393 338.697 201.312 1.00 90.07  ? 72   LEU C CG    1 
ATOM   8227  C CD1   . LEU B 2 72   ? 200.665 339.505 200.053 1.00 90.07  ? 72   LEU C CD1   1 
ATOM   8228  C CD2   . LEU B 2 72   ? 200.203 337.235 200.951 1.00 90.07  ? 72   LEU C CD2   1 
ATOM   8229  N N     . LYS B 2 73   ? 199.993 341.625 202.754 1.00 85.48  ? 73   LYS C N     1 
ATOM   8230  C CA    . LYS B 2 73   ? 199.614 342.965 202.318 1.00 85.48  ? 73   LYS C CA    1 
ATOM   8231  C C     . LYS B 2 73   ? 200.157 344.024 203.270 1.00 85.48  ? 73   LYS C C     1 
ATOM   8232  O O     . LYS B 2 73   ? 200.667 345.065 202.832 1.00 85.48  ? 73   LYS C O     1 
ATOM   8233  C CB    . LYS B 2 73   ? 198.093 343.071 202.205 1.00 85.48  ? 73   LYS C CB    1 
ATOM   8234  N N     . GLU B 2 74   ? 200.067 343.770 204.578 1.00 87.97  ? 74   GLU C N     1 
ATOM   8235  C CA    . GLU B 2 74   ? 200.568 344.730 205.556 1.00 87.97  ? 74   GLU C CA    1 
ATOM   8236  C C     . GLU B 2 74   ? 202.074 344.923 205.426 1.00 87.97  ? 74   GLU C C     1 
ATOM   8237  O O     . GLU B 2 74   ? 202.566 346.057 205.467 1.00 87.97  ? 74   GLU C O     1 
ATOM   8238  C CB    . GLU B 2 74   ? 200.206 344.277 206.970 1.00 87.97  ? 74   GLU C CB    1 
ATOM   8239  N N     . VAL B 2 75   ? 202.824 343.830 205.265 1.00 92.42  ? 75   VAL C N     1 
ATOM   8240  C CA    . VAL B 2 75   ? 204.277 343.945 205.164 1.00 92.42  ? 75   VAL C CA    1 
ATOM   8241  C C     . VAL B 2 75   ? 204.672 344.624 203.856 1.00 92.42  ? 75   VAL C C     1 
ATOM   8242  O O     . VAL B 2 75   ? 205.619 345.419 203.821 1.00 92.42  ? 75   VAL C O     1 
ATOM   8243  C CB    . VAL B 2 75   ? 204.951 342.567 205.340 1.00 92.42  ? 75   VAL C CB    1 
ATOM   8244  C CG1   . VAL B 2 75   ? 204.720 341.667 204.142 1.00 92.42  ? 75   VAL C CG1   1 
ATOM   8245  C CG2   . VAL B 2 75   ? 206.442 342.733 205.585 1.00 92.42  ? 75   VAL C CG2   1 
ATOM   8246  N N     . ASP B 2 76   ? 203.944 344.348 202.768 1.00 97.46  ? 76   ASP C N     1 
ATOM   8247  C CA    . ASP B 2 76   ? 204.225 345.027 201.507 1.00 97.46  ? 76   ASP C CA    1 
ATOM   8248  C C     . ASP B 2 76   ? 203.979 346.525 201.624 1.00 97.46  ? 76   ASP C C     1 
ATOM   8249  O O     . ASP B 2 76   ? 204.783 347.335 201.145 1.00 97.46  ? 76   ASP C O     1 
ATOM   8250  C CB    . ASP B 2 76   ? 203.374 344.427 200.388 1.00 97.46  ? 76   ASP C CB    1 
ATOM   8251  C CG    . ASP B 2 76   ? 203.909 343.096 199.898 1.00 97.46  ? 76   ASP C CG    1 
ATOM   8252  O OD1   . ASP B 2 76   ? 205.142 342.973 199.740 1.00 97.46  ? 76   ASP C OD1   1 
ATOM   8253  O OD2   . ASP B 2 76   ? 203.099 342.174 199.672 1.00 97.46  ? 76   ASP C OD2   1 
ATOM   8254  N N     . ILE B 2 77   ? 202.879 346.916 202.273 1.00 96.55  ? 77   ILE C N     1 
ATOM   8255  C CA    . ILE B 2 77   ? 202.582 348.337 202.428 1.00 96.55  ? 77   ILE C CA    1 
ATOM   8256  C C     . ILE B 2 77   ? 203.609 349.005 203.333 1.00 96.55  ? 77   ILE C C     1 
ATOM   8257  O O     . ILE B 2 77   ? 204.056 350.128 203.068 1.00 96.55  ? 77   ILE C O     1 
ATOM   8258  C CB    . ILE B 2 77   ? 201.147 348.525 202.953 1.00 96.55  ? 77   ILE C CB    1 
ATOM   8259  C CG1   . ILE B 2 77   ? 200.171 348.637 201.784 1.00 96.55  ? 77   ILE C CG1   1 
ATOM   8260  C CG2   . ILE B 2 77   ? 201.046 349.753 203.852 1.00 96.55  ? 77   ILE C CG2   1 
ATOM   8261  C CD1   . ILE B 2 77   ? 198.737 348.735 202.210 1.00 96.55  ? 77   ILE C CD1   1 
ATOM   8262  N N     . LEU B 2 78   ? 204.017 348.320 204.405 1.00 98.10  ? 78   LEU C N     1 
ATOM   8263  C CA    . LEU B 2 78   ? 204.991 348.900 205.323 1.00 98.10  ? 78   LEU C CA    1 
ATOM   8264  C C     . LEU B 2 78   ? 206.350 349.061 204.653 1.00 98.10  ? 78   LEU C C     1 
ATOM   8265  O O     . LEU B 2 78   ? 207.058 350.045 204.897 1.00 98.10  ? 78   LEU C O     1 
ATOM   8266  C CB    . LEU B 2 78   ? 205.099 348.043 206.584 1.00 98.10  ? 78   LEU C CB    1 
ATOM   8267  C CG    . LEU B 2 78   ? 204.711 348.753 207.885 1.00 98.10  ? 78   LEU C CG    1 
ATOM   8268  C CD1   . LEU B 2 78   ? 205.093 347.925 209.100 1.00 98.10  ? 78   LEU C CD1   1 
ATOM   8269  C CD2   . LEU B 2 78   ? 205.350 350.133 207.956 1.00 98.10  ? 78   LEU C CD2   1 
ATOM   8270  N N     . ARG B 2 79   ? 206.735 348.102 203.806 1.00 99.64  ? 79   ARG C N     1 
ATOM   8271  C CA    . ARG B 2 79   ? 207.956 348.258 203.026 1.00 99.64  ? 79   ARG C CA    1 
ATOM   8272  C C     . ARG B 2 79   ? 207.821 349.367 201.989 1.00 99.64  ? 79   ARG C C     1 
ATOM   8273  O O     . ARG B 2 79   ? 208.813 350.024 201.655 1.00 99.64  ? 79   ARG C O     1 
ATOM   8274  C CB    . ARG B 2 79   ? 208.322 346.938 202.348 1.00 99.64  ? 79   ARG C CB    1 
ATOM   8275  N N     . LYS B 2 80   ? 206.610 349.584 201.466 1.00 101.48 ? 80   LYS C N     1 
ATOM   8276  C CA    . LYS B 2 80   ? 206.407 350.647 200.486 1.00 101.48 ? 80   LYS C CA    1 
ATOM   8277  C C     . LYS B 2 80   ? 206.682 352.021 201.086 1.00 101.48 ? 80   LYS C C     1 
ATOM   8278  O O     . LYS B 2 80   ? 207.296 352.877 200.439 1.00 101.48 ? 80   LYS C O     1 
ATOM   8279  C CB    . LYS B 2 80   ? 204.985 350.586 199.927 1.00 101.48 ? 80   LYS C CB    1 
ATOM   8280  C CG    . LYS B 2 80   ? 204.897 350.077 198.498 1.00 101.48 ? 80   LYS C CG    1 
ATOM   8281  C CD    . LYS B 2 80   ? 203.479 350.187 197.962 1.00 101.48 ? 80   LYS C CD    1 
ATOM   8282  C CE    . LYS B 2 80   ? 203.379 349.651 196.543 1.00 101.48 ? 80   LYS C CE    1 
ATOM   8283  N NZ    . LYS B 2 80   ? 201.965 349.470 196.114 1.00 101.48 ? 80   LYS C NZ    1 
ATOM   8284  N N     . VAL B 2 81   ? 206.238 352.251 202.317 1.00 108.72 ? 81   VAL C N     1 
ATOM   8285  C CA    . VAL B 2 81   ? 206.395 353.543 202.970 1.00 108.72 ? 81   VAL C CA    1 
ATOM   8286  C C     . VAL B 2 81   ? 207.588 353.548 203.929 1.00 108.72 ? 81   VAL C C     1 
ATOM   8287  O O     . VAL B 2 81   ? 207.712 354.449 204.758 1.00 108.72 ? 81   VAL C O     1 
ATOM   8288  C CB    . VAL B 2 81   ? 205.104 353.972 203.684 1.00 108.72 ? 81   VAL C CB    1 
ATOM   8289  C CG1   . VAL B 2 81   ? 203.923 353.891 202.730 1.00 108.72 ? 81   VAL C CG1   1 
ATOM   8290  C CG2   . VAL B 2 81   ? 204.856 353.102 204.908 1.00 108.72 ? 81   VAL C CG2   1 
ATOM   8291  N N     . SER B 2 82   ? 208.471 352.558 203.823 1.00 117.84 ? 82   SER C N     1 
ATOM   8292  C CA    . SER B 2 82   ? 209.635 352.495 204.695 1.00 117.84 ? 82   SER C CA    1 
ATOM   8293  C C     . SER B 2 82   ? 210.575 353.666 204.424 1.00 117.84 ? 82   SER C C     1 
ATOM   8294  O O     . SER B 2 82   ? 210.673 354.170 203.302 1.00 117.84 ? 82   SER C O     1 
ATOM   8295  C CB    . SER B 2 82   ? 210.375 351.171 204.501 1.00 117.84 ? 82   SER C CB    1 
ATOM   8296  O OG    . SER B 2 82   ? 211.522 351.102 205.330 1.00 117.84 ? 82   SER C OG    1 
ATOM   8297  N N     . GLY B 2 83   ? 211.272 354.098 205.474 1.00 114.98 ? 83   GLY C N     1 
ATOM   8298  C CA    . GLY B 2 83   ? 212.185 355.216 205.397 1.00 114.98 ? 83   GLY C CA    1 
ATOM   8299  C C     . GLY B 2 83   ? 211.660 356.509 205.983 1.00 114.98 ? 83   GLY C C     1 
ATOM   8300  O O     . GLY B 2 83   ? 212.454 357.426 206.226 1.00 114.98 ? 83   GLY C O     1 
ATOM   8301  N N     . HIS B 2 84   ? 210.357 356.611 206.216 1.00 111.37 ? 84   HIS C N     1 
ATOM   8302  C CA    . HIS B 2 84   ? 209.791 357.802 206.834 1.00 111.37 ? 84   HIS C CA    1 
ATOM   8303  C C     . HIS B 2 84   ? 210.032 357.754 208.338 1.00 111.37 ? 84   HIS C C     1 
ATOM   8304  O O     . HIS B 2 84   ? 209.547 356.830 209.001 1.00 111.37 ? 84   HIS C O     1 
ATOM   8305  C CB    . HIS B 2 84   ? 208.299 357.895 206.537 1.00 111.37 ? 84   HIS C CB    1 
ATOM   8306  C CG    . HIS B 2 84   ? 207.726 359.268 206.706 1.00 111.37 ? 84   HIS C CG    1 
ATOM   8307  N ND1   . HIS B 2 84   ? 208.274 360.207 207.554 1.00 111.37 ? 84   HIS C ND1   1 
ATOM   8308  C CD2   . HIS B 2 84   ? 206.650 359.860 206.135 1.00 111.37 ? 84   HIS C CD2   1 
ATOM   8309  C CE1   . HIS B 2 84   ? 207.561 361.318 207.498 1.00 111.37 ? 84   HIS C CE1   1 
ATOM   8310  N NE2   . HIS B 2 84   ? 206.570 361.134 206.644 1.00 111.37 ? 84   HIS C NE2   1 
ATOM   8311  N N     . PRO B 2 85   ? 210.780 358.702 208.910 1.00 113.30 ? 85   PRO C N     1 
ATOM   8312  C CA    . PRO B 2 85   ? 211.007 358.666 210.366 1.00 113.30 ? 85   PRO C CA    1 
ATOM   8313  C C     . PRO B 2 85   ? 209.733 358.792 211.183 1.00 113.30 ? 85   PRO C C     1 
ATOM   8314  O O     . PRO B 2 85   ? 209.622 358.177 212.251 1.00 113.30 ? 85   PRO C O     1 
ATOM   8315  C CB    . PRO B 2 85   ? 211.953 359.854 210.600 1.00 113.30 ? 85   PRO C CB    1 
ATOM   8316  C CG    . PRO B 2 85   ? 211.738 360.753 209.426 1.00 113.30 ? 85   PRO C CG    1 
ATOM   8317  C CD    . PRO B 2 85   ? 211.454 359.844 208.270 1.00 113.30 ? 85   PRO C CD    1 
ATOM   8318  N N     . ASN B 2 86   ? 208.764 359.577 210.710 1.00 105.69 ? 86   ASN C N     1 
ATOM   8319  C CA    . ASN B 2 86   ? 207.540 359.779 211.477 1.00 105.69 ? 86   ASN C CA    1 
ATOM   8320  C C     . ASN B 2 86   ? 206.612 358.574 211.374 1.00 105.69 ? 86   ASN C C     1 
ATOM   8321  O O     . ASN B 2 86   ? 205.866 358.287 212.317 1.00 105.69 ? 86   ASN C O     1 
ATOM   8322  C CB    . ASN B 2 86   ? 206.851 361.064 211.010 1.00 105.69 ? 86   ASN C CB    1 
ATOM   8323  C CG    . ASN B 2 86   ? 205.379 361.116 211.372 1.00 105.69 ? 86   ASN C CG    1 
ATOM   8324  O OD1   . ASN B 2 86   ? 204.550 361.503 210.553 1.00 105.69 ? 86   ASN C OD1   1 
ATOM   8325  N ND2   . ASN B 2 86   ? 205.053 360.766 212.613 1.00 105.69 ? 86   ASN C ND2   1 
ATOM   8326  N N     . ILE B 2 87   ? 206.643 357.864 210.251 1.00 100.73 ? 87   ILE C N     1 
ATOM   8327  C CA    . ILE B 2 87   ? 205.909 356.616 210.081 1.00 100.73 ? 87   ILE C CA    1 
ATOM   8328  C C     . ILE B 2 87   ? 206.704 355.500 210.745 1.00 100.73 ? 87   ILE C C     1 
ATOM   8329  O O     . ILE B 2 87   ? 207.936 355.550 210.819 1.00 100.73 ? 87   ILE C O     1 
ATOM   8330  C CB    . ILE B 2 87   ? 205.658 356.328 208.584 1.00 100.73 ? 87   ILE C CB    1 
ATOM   8331  C CG1   . ILE B 2 87   ? 204.860 357.466 207.945 1.00 100.73 ? 87   ILE C CG1   1 
ATOM   8332  C CG2   . ILE B 2 87   ? 204.921 355.009 208.384 1.00 100.73 ? 87   ILE C CG2   1 
ATOM   8333  C CD1   . ILE B 2 87   ? 203.390 357.446 208.289 1.00 100.73 ? 87   ILE C CD1   1 
ATOM   8334  N N     . ILE B 2 88   ? 205.998 354.487 211.253 1.00 95.91  ? 88   ILE C N     1 
ATOM   8335  C CA    . ILE B 2 88   ? 206.674 353.336 211.837 1.00 95.91  ? 88   ILE C CA    1 
ATOM   8336  C C     . ILE B 2 88   ? 207.498 352.628 210.764 1.00 95.91  ? 88   ILE C C     1 
ATOM   8337  O O     . ILE B 2 88   ? 207.197 352.696 209.564 1.00 95.91  ? 88   ILE C O     1 
ATOM   8338  C CB    . ILE B 2 88   ? 205.659 352.382 212.495 1.00 95.91  ? 88   ILE C CB    1 
ATOM   8339  C CG1   . ILE B 2 88   ? 206.259 351.755 213.755 1.00 95.91  ? 88   ILE C CG1   1 
ATOM   8340  C CG2   . ILE B 2 88   ? 205.200 351.306 211.518 1.00 95.91  ? 88   ILE C CG2   1 
ATOM   8341  C CD1   . ILE B 2 88   ? 205.354 350.745 214.426 1.00 95.91  ? 88   ILE C CD1   1 
ATOM   8342  N N     . GLN B 2 89   ? 208.565 351.962 211.197 1.00 88.70  ? 89   GLN C N     1 
ATOM   8343  C CA    . GLN B 2 89   ? 209.509 351.313 210.297 1.00 88.70  ? 89   GLN C CA    1 
ATOM   8344  C C     . GLN B 2 89   ? 209.611 349.835 210.641 1.00 88.70  ? 89   GLN C C     1 
ATOM   8345  O O     . GLN B 2 89   ? 209.705 349.472 211.818 1.00 88.70  ? 89   GLN C O     1 
ATOM   8346  C CB    . GLN B 2 89   ? 210.889 351.973 210.378 1.00 88.70  ? 89   GLN C CB    1 
ATOM   8347  N N     . LEU B 2 90   ? 209.593 348.989 209.612 1.00 84.41  ? 90   LEU C N     1 
ATOM   8348  C CA    . LEU B 2 90   ? 209.678 347.540 209.783 1.00 84.41  ? 90   LEU C CA    1 
ATOM   8349  C C     . LEU B 2 90   ? 211.091 347.122 209.390 1.00 84.41  ? 90   LEU C C     1 
ATOM   8350  O O     . LEU B 2 90   ? 211.413 346.970 208.210 1.00 84.41  ? 90   LEU C O     1 
ATOM   8351  C CB    . LEU B 2 90   ? 208.602 346.846 208.953 1.00 84.41  ? 90   LEU C CB    1 
ATOM   8352  C CG    . LEU B 2 90   ? 208.151 345.411 209.252 1.00 84.41  ? 90   LEU C CG    1 
ATOM   8353  C CD1   . LEU B 2 90   ? 207.075 344.999 208.267 1.00 84.41  ? 90   LEU C CD1   1 
ATOM   8354  C CD2   . LEU B 2 90   ? 209.291 344.412 209.210 1.00 84.41  ? 90   LEU C CD2   1 
ATOM   8355  N N     . LYS B 2 91   ? 211.946 346.936 210.398 1.00 80.99  ? 91   LYS C N     1 
ATOM   8356  C CA    . LYS B 2 91   ? 213.354 346.650 210.139 1.00 80.99  ? 91   LYS C CA    1 
ATOM   8357  C C     . LYS B 2 91   ? 213.539 345.277 209.502 1.00 80.99  ? 91   LYS C C     1 
ATOM   8358  O O     . LYS B 2 91   ? 214.233 345.140 208.488 1.00 80.99  ? 91   LYS C O     1 
ATOM   8359  C CB    . LYS B 2 91   ? 214.154 346.752 211.439 1.00 80.99  ? 91   LYS C CB    1 
ATOM   8360  N N     . ASP B 2 92   ? 212.924 344.248 210.081 1.00 86.79  ? 92   ASP C N     1 
ATOM   8361  C CA    . ASP B 2 92   ? 213.095 342.883 209.605 1.00 86.79  ? 92   ASP C CA    1 
ATOM   8362  C C     . ASP B 2 92   ? 211.799 342.108 209.783 1.00 86.79  ? 92   ASP C C     1 
ATOM   8363  O O     . ASP B 2 92   ? 211.095 342.282 210.782 1.00 86.79  ? 92   ASP C O     1 
ATOM   8364  C CB    . ASP B 2 92   ? 214.235 342.172 210.347 1.00 86.79  ? 92   ASP C CB    1 
ATOM   8365  N N     . THR B 2 93   ? 211.494 341.250 208.813 1.00 84.16  ? 93   THR C N     1 
ATOM   8366  C CA    . THR B 2 93   ? 210.290 340.432 208.834 1.00 84.16  ? 93   THR C CA    1 
ATOM   8367  C C     . THR B 2 93   ? 210.660 338.972 208.623 1.00 84.16  ? 93   THR C C     1 
ATOM   8368  O O     . THR B 2 93   ? 211.543 338.654 207.821 1.00 84.16  ? 93   THR C O     1 
ATOM   8369  C CB    . THR B 2 93   ? 209.285 340.882 207.762 1.00 84.16  ? 93   THR C CB    1 
ATOM   8370  O OG1   . THR B 2 93   ? 208.229 339.919 207.658 1.00 84.16  ? 93   THR C OG1   1 
ATOM   8371  C CG2   . THR B 2 93   ? 209.970 341.036 206.411 1.00 84.16  ? 93   THR C CG2   1 
ATOM   8372  N N     . TYR B 2 94   ? 209.982 338.088 209.352 1.00 87.90  ? 94   TYR C N     1 
ATOM   8373  C CA    . TYR B 2 94   ? 210.226 336.656 209.280 1.00 87.90  ? 94   TYR C CA    1 
ATOM   8374  C C     . TYR B 2 94   ? 208.899 335.918 209.184 1.00 87.90  ? 94   TYR C C     1 
ATOM   8375  O O     . TYR B 2 94   ? 207.888 336.350 209.745 1.00 87.90  ? 94   TYR C O     1 
ATOM   8376  C CB    . TYR B 2 94   ? 211.012 336.159 210.500 1.00 87.90  ? 94   TYR C CB    1 
ATOM   8377  C CG    . TYR B 2 94   ? 212.413 336.720 210.597 1.00 87.90  ? 94   TYR C CG    1 
ATOM   8378  C CD1   . TYR B 2 94   ? 213.294 336.629 209.528 1.00 87.90  ? 94   TYR C CD1   1 
ATOM   8379  C CD2   . TYR B 2 94   ? 212.850 337.349 211.756 1.00 87.90  ? 94   TYR C CD2   1 
ATOM   8380  C CE1   . TYR B 2 94   ? 214.575 337.143 209.613 1.00 87.90  ? 94   TYR C CE1   1 
ATOM   8381  C CE2   . TYR B 2 94   ? 214.128 337.865 211.850 1.00 87.90  ? 94   TYR C CE2   1 
ATOM   8382  C CZ    . TYR B 2 94   ? 214.986 337.760 210.776 1.00 87.90  ? 94   TYR C CZ    1 
ATOM   8383  O OH    . TYR B 2 94   ? 216.259 338.273 210.865 1.00 87.90  ? 94   TYR C OH    1 
ATOM   8384  N N     . GLU B 2 95   ? 208.910 334.799 208.464 1.00 84.89  ? 95   GLU C N     1 
ATOM   8385  C CA    . GLU B 2 95   ? 207.718 333.982 208.292 1.00 84.89  ? 95   GLU C CA    1 
ATOM   8386  C C     . GLU B 2 95   ? 208.080 332.512 208.443 1.00 84.89  ? 95   GLU C C     1 
ATOM   8387  O O     . GLU B 2 95   ? 209.026 332.030 207.813 1.00 84.89  ? 95   GLU C O     1 
ATOM   8388  C CB    . GLU B 2 95   ? 207.067 334.223 206.924 1.00 84.89  ? 95   GLU C CB    1 
ATOM   8389  N N     . THR B 2 96   ? 207.322 331.808 209.280 1.00 83.24  ? 96   THR C N     1 
ATOM   8390  C CA    . THR B 2 96   ? 207.474 330.373 209.470 1.00 83.24  ? 96   THR C CA    1 
ATOM   8391  C C     . THR B 2 96   ? 206.152 329.688 209.152 1.00 83.24  ? 96   THR C C     1 
ATOM   8392  O O     . THR B 2 96   ? 205.174 330.327 208.754 1.00 83.24  ? 96   THR C O     1 
ATOM   8393  C CB    . THR B 2 96   ? 207.924 330.027 210.898 1.00 83.24  ? 96   THR C CB    1 
ATOM   8394  O OG1   . THR B 2 96   ? 206.781 329.967 211.761 1.00 83.24  ? 96   THR C OG1   1 
ATOM   8395  C CG2   . THR B 2 96   ? 208.901 331.069 211.426 1.00 83.24  ? 96   THR C CG2   1 
ATOM   8396  N N     . ASN B 2 97   ? 206.133 328.365 209.326 1.00 82.43  ? 97   ASN C N     1 
ATOM   8397  C CA    . ASN B 2 97   ? 204.941 327.593 208.991 1.00 82.43  ? 97   ASN C CA    1 
ATOM   8398  C C     . ASN B 2 97   ? 203.766 327.955 209.893 1.00 82.43  ? 97   ASN C C     1 
ATOM   8399  O O     . ASN B 2 97   ? 202.635 328.112 209.418 1.00 82.43  ? 97   ASN C O     1 
ATOM   8400  C CB    . ASN B 2 97   ? 205.244 326.097 209.076 1.00 82.43  ? 97   ASN C CB    1 
ATOM   8401  C CG    . ASN B 2 97   ? 204.083 325.239 208.609 1.00 82.43  ? 97   ASN C CG    1 
ATOM   8402  O OD1   . ASN B 2 97   ? 203.382 324.629 209.416 1.00 82.43  ? 97   ASN C OD1   1 
ATOM   8403  N ND2   . ASN B 2 97   ? 203.875 325.190 207.299 1.00 82.43  ? 97   ASN C ND2   1 
ATOM   8404  N N     . THR B 2 98   ? 204.012 328.093 211.200 1.00 78.58  ? 98   THR C N     1 
ATOM   8405  C CA    . THR B 2 98   ? 202.949 328.383 212.152 1.00 78.58  ? 98   THR C CA    1 
ATOM   8406  C C     . THR B 2 98   ? 203.190 329.631 212.992 1.00 78.58  ? 98   THR C C     1 
ATOM   8407  O O     . THR B 2 98   ? 202.389 329.910 213.891 1.00 78.58  ? 98   THR C O     1 
ATOM   8408  C CB    . THR B 2 98   ? 202.726 327.192 213.100 1.00 78.58  ? 98   THR C CB    1 
ATOM   8409  O OG1   . THR B 2 98   ? 203.775 327.149 214.075 1.00 78.58  ? 98   THR C OG1   1 
ATOM   8410  C CG2   . THR B 2 98   ? 202.695 325.882 212.329 1.00 78.58  ? 98   THR C CG2   1 
ATOM   8411  N N     . PHE B 2 99   ? 204.257 330.384 212.736 1.00 77.57  ? 99   PHE C N     1 
ATOM   8412  C CA    . PHE B 2 99   ? 204.550 331.581 213.510 1.00 77.57  ? 99   PHE C CA    1 
ATOM   8413  C C     . PHE B 2 99   ? 205.077 332.671 212.589 1.00 77.57  ? 99   PHE C C     1 
ATOM   8414  O O     . PHE B 2 99   ? 205.903 332.406 211.711 1.00 77.57  ? 99   PHE C O     1 
ATOM   8415  C CB    . PHE B 2 99   ? 205.570 331.294 214.619 1.00 77.57  ? 99   PHE C CB    1 
ATOM   8416  C CG    . PHE B 2 99   ? 204.951 331.057 215.967 1.00 77.57  ? 99   PHE C CG    1 
ATOM   8417  C CD1   . PHE B 2 99   ? 203.983 331.916 216.459 1.00 77.57  ? 99   PHE C CD1   1 
ATOM   8418  C CD2   . PHE B 2 99   ? 205.338 329.977 216.742 1.00 77.57  ? 99   PHE C CD2   1 
ATOM   8419  C CE1   . PHE B 2 99   ? 203.411 331.702 217.700 1.00 77.57  ? 99   PHE C CE1   1 
ATOM   8420  C CE2   . PHE B 2 99   ? 204.771 329.758 217.983 1.00 77.57  ? 99   PHE C CE2   1 
ATOM   8421  C CZ    . PHE B 2 99   ? 203.806 330.622 218.462 1.00 77.57  ? 99   PHE C CZ    1 
ATOM   8422  N N     . PHE B 2 100  ? 204.594 333.892 212.793 1.00 82.32  ? 100  PHE C N     1 
ATOM   8423  C CA    . PHE B 2 100  ? 205.051 335.062 212.055 1.00 82.32  ? 100  PHE C CA    1 
ATOM   8424  C C     . PHE B 2 100  ? 205.810 335.986 212.996 1.00 82.32  ? 100  PHE C C     1 
ATOM   8425  O O     . PHE B 2 100  ? 205.315 336.318 214.079 1.00 82.32  ? 100  PHE C O     1 
ATOM   8426  C CB    . PHE B 2 100  ? 203.882 335.812 211.406 1.00 82.32  ? 100  PHE C CB    1 
ATOM   8427  C CG    . PHE B 2 100  ? 203.312 335.133 210.185 1.00 82.32  ? 100  PHE C CG    1 
ATOM   8428  C CD1   . PHE B 2 100  ? 203.186 333.756 210.119 1.00 82.32  ? 100  PHE C CD1   1 
ATOM   8429  C CD2   . PHE B 2 100  ? 202.902 335.887 209.097 1.00 82.32  ? 100  PHE C CD2   1 
ATOM   8430  C CE1   . PHE B 2 100  ? 202.666 333.144 208.994 1.00 82.32  ? 100  PHE C CE1   1 
ATOM   8431  C CE2   . PHE B 2 100  ? 202.380 335.280 207.971 1.00 82.32  ? 100  PHE C CE2   1 
ATOM   8432  C CZ    . PHE B 2 100  ? 202.260 333.908 207.920 1.00 82.32  ? 100  PHE C CZ    1 
ATOM   8433  N N     . PHE B 2 101  ? 207.006 336.396 212.584 1.00 77.40  ? 101  PHE C N     1 
ATOM   8434  C CA    . PHE B 2 101  ? 207.855 337.277 213.372 1.00 77.40  ? 101  PHE C CA    1 
ATOM   8435  C C     . PHE B 2 101  ? 208.096 338.567 212.603 1.00 77.40  ? 101  PHE C C     1 
ATOM   8436  O O     . PHE B 2 101  ? 208.589 338.537 211.471 1.00 77.40  ? 101  PHE C O     1 
ATOM   8437  C CB    . PHE B 2 101  ? 209.191 336.607 213.709 1.00 77.40  ? 101  PHE C CB    1 
ATOM   8438  C CG    . PHE B 2 101  ? 209.054 335.357 214.531 1.00 77.40  ? 101  PHE C CG    1 
ATOM   8439  C CD1   . PHE B 2 101  ? 208.851 334.129 213.923 1.00 77.40  ? 101  PHE C CD1   1 
ATOM   8440  C CD2   . PHE B 2 101  ? 209.131 335.409 215.913 1.00 77.40  ? 101  PHE C CD2   1 
ATOM   8441  C CE1   . PHE B 2 101  ? 208.726 332.978 214.677 1.00 77.40  ? 101  PHE C CE1   1 
ATOM   8442  C CE2   . PHE B 2 101  ? 209.007 334.261 216.673 1.00 77.40  ? 101  PHE C CE2   1 
ATOM   8443  C CZ    . PHE B 2 101  ? 208.804 333.044 216.054 1.00 77.40  ? 101  PHE C CZ    1 
ATOM   8444  N N     . LEU B 2 102  ? 207.748 339.694 213.219 1.00 77.60  ? 102  LEU C N     1 
ATOM   8445  C CA    . LEU B 2 102  ? 207.993 341.010 212.650 1.00 77.60  ? 102  LEU C CA    1 
ATOM   8446  C C     . LEU B 2 102  ? 208.728 341.860 213.675 1.00 77.60  ? 102  LEU C C     1 
ATOM   8447  O O     . LEU B 2 102  ? 208.466 341.773 214.877 1.00 77.60  ? 102  LEU C O     1 
ATOM   8448  C CB    . LEU B 2 102  ? 206.690 341.718 212.226 1.00 77.60  ? 102  LEU C CB    1 
ATOM   8449  C CG    . LEU B 2 102  ? 205.812 341.151 211.101 1.00 77.60  ? 102  LEU C CG    1 
ATOM   8450  C CD1   . LEU B 2 102  ? 205.096 339.865 211.499 1.00 77.60  ? 102  LEU C CD1   1 
ATOM   8451  C CD2   . LEU B 2 102  ? 204.810 342.199 210.634 1.00 77.60  ? 102  LEU C CD2   1 
ATOM   8452  N N     . VAL B 2 103  ? 209.650 342.687 213.190 1.00 82.77  ? 103  VAL C N     1 
ATOM   8453  C CA    . VAL B 2 103  ? 210.501 343.509 214.042 1.00 82.77  ? 103  VAL C CA    1 
ATOM   8454  C C     . VAL B 2 103  ? 210.121 344.969 213.846 1.00 82.77  ? 103  VAL C C     1 
ATOM   8455  O O     . VAL B 2 103  ? 210.082 345.460 212.711 1.00 82.77  ? 103  VAL C O     1 
ATOM   8456  C CB    . VAL B 2 103  ? 211.995 343.288 213.740 1.00 82.77  ? 103  VAL C CB    1 
ATOM   8457  C CG1   . VAL B 2 103  ? 212.855 344.093 214.703 1.00 82.77  ? 103  VAL C CG1   1 
ATOM   8458  C CG2   . VAL B 2 103  ? 212.338 341.809 213.820 1.00 82.77  ? 103  VAL C CG2   1 
ATOM   8459  N N     . PHE B 2 104  ? 209.842 345.658 214.952 1.00 85.75  ? 104  PHE C N     1 
ATOM   8460  C CA    . PHE B 2 104  ? 209.532 347.081 214.920 1.00 85.75  ? 104  PHE C CA    1 
ATOM   8461  C C     . PHE B 2 104  ? 210.452 347.835 215.871 1.00 85.75  ? 104  PHE C C     1 
ATOM   8462  O O     . PHE B 2 104  ? 211.403 347.259 216.409 1.00 85.75  ? 104  PHE C O     1 
ATOM   8463  C CB    . PHE B 2 104  ? 208.067 347.328 215.291 1.00 85.75  ? 104  PHE C CB    1 
ATOM   8464  C CG    . PHE B 2 104  ? 207.085 346.657 214.373 1.00 85.75  ? 104  PHE C CG    1 
ATOM   8465  C CD1   . PHE B 2 104  ? 206.637 345.373 214.636 1.00 85.75  ? 104  PHE C CD1   1 
ATOM   8466  C CD2   . PHE B 2 104  ? 206.609 347.311 213.250 1.00 85.75  ? 104  PHE C CD2   1 
ATOM   8467  C CE1   . PHE B 2 104  ? 205.732 344.754 213.795 1.00 85.75  ? 104  PHE C CE1   1 
ATOM   8468  C CE2   . PHE B 2 104  ? 205.704 346.697 212.405 1.00 85.75  ? 104  PHE C CE2   1 
ATOM   8469  C CZ    . PHE B 2 104  ? 205.266 345.417 212.677 1.00 85.75  ? 104  PHE C CZ    1 
ATOM   8470  N N     . ASP B 2 105  ? 210.180 349.118 216.083 1.00 93.79  ? 105  ASP C N     1 
ATOM   8471  C CA    . ASP B 2 105  ? 210.950 349.940 217.007 1.00 93.79  ? 105  ASP C CA    1 
ATOM   8472  C C     . ASP B 2 105  ? 210.173 350.080 218.311 1.00 93.79  ? 105  ASP C C     1 
ATOM   8473  O O     . ASP B 2 105  ? 209.094 350.683 218.333 1.00 93.79  ? 105  ASP C O     1 
ATOM   8474  C CB    . ASP B 2 105  ? 211.244 351.313 216.401 1.00 93.79  ? 105  ASP C CB    1 
ATOM   8475  C CG    . ASP B 2 105  ? 210.104 351.830 215.545 1.00 93.79  ? 105  ASP C CG    1 
ATOM   8476  O OD1   . ASP B 2 105  ? 209.025 351.200 215.542 1.00 93.79  ? 105  ASP C OD1   1 
ATOM   8477  O OD2   . ASP B 2 105  ? 210.287 352.867 214.873 1.00 93.79  ? 105  ASP C OD2   1 
ATOM   8478  N N     . LEU B 2 106  ? 210.718 349.521 219.388 1.00 92.90  ? 106  LEU C N     1 
ATOM   8479  C CA    . LEU B 2 106  ? 210.062 349.606 220.685 1.00 92.90  ? 106  LEU C CA    1 
ATOM   8480  C C     . LEU B 2 106  ? 210.089 351.038 221.202 1.00 92.90  ? 106  LEU C C     1 
ATOM   8481  O O     . LEU B 2 106  ? 211.079 351.757 221.043 1.00 92.90  ? 106  LEU C O     1 
ATOM   8482  C CB    . LEU B 2 106  ? 210.735 348.672 221.689 1.00 92.90  ? 106  LEU C CB    1 
ATOM   8483  N N     . MET B 2 107  ? 208.988 351.450 221.824 1.00 93.55  ? 107  MET C N     1 
ATOM   8484  C CA    . MET B 2 107  ? 208.813 352.813 222.306 1.00 93.55  ? 107  MET C CA    1 
ATOM   8485  C C     . MET B 2 107  ? 208.451 352.776 223.783 1.00 93.55  ? 107  MET C C     1 
ATOM   8486  O O     . MET B 2 107  ? 207.590 351.991 224.196 1.00 93.55  ? 107  MET C O     1 
ATOM   8487  C CB    . MET B 2 107  ? 207.737 353.534 221.491 1.00 93.55  ? 107  MET C CB    1 
ATOM   8488  C CG    . MET B 2 107  ? 207.935 353.382 219.988 1.00 93.55  ? 107  MET C CG    1 
ATOM   8489  S SD    . MET B 2 107  ? 206.428 353.563 219.019 1.00 93.55  ? 107  MET C SD    1 
ATOM   8490  C CE    . MET B 2 107  ? 205.608 354.867 219.921 1.00 93.55  ? 107  MET C CE    1 
ATOM   8491  N N     . LYS B 2 108  ? 209.111 353.624 224.575 1.00 96.21  ? 108  LYS C N     1 
ATOM   8492  C CA    . LYS B 2 108  ? 208.955 353.575 226.025 1.00 96.21  ? 108  LYS C CA    1 
ATOM   8493  C C     . LYS B 2 108  ? 207.607 354.107 226.495 1.00 96.21  ? 108  LYS C C     1 
ATOM   8494  O O     . LYS B 2 108  ? 207.189 353.790 227.613 1.00 96.21  ? 108  LYS C O     1 
ATOM   8495  C CB    . LYS B 2 108  ? 210.083 354.357 226.700 1.00 96.21  ? 108  LYS C CB    1 
ATOM   8496  N N     . ARG B 2 109  ? 206.921 354.901 225.679 1.00 93.32  ? 109  ARG C N     1 
ATOM   8497  C CA    . ARG B 2 109  ? 205.639 355.475 226.055 1.00 93.32  ? 109  ARG C CA    1 
ATOM   8498  C C     . ARG B 2 109  ? 204.496 354.656 225.466 1.00 93.32  ? 109  ARG C C     1 
ATOM   8499  O O     . ARG B 2 109  ? 204.666 353.935 224.480 1.00 93.32  ? 109  ARG C O     1 
ATOM   8500  C CB    . ARG B 2 109  ? 205.533 356.930 225.595 1.00 93.32  ? 109  ARG C CB    1 
ATOM   8501  N N     . GLY B 2 110  ? 203.326 354.777 226.085 1.00 91.05  ? 110  GLY C N     1 
ATOM   8502  C CA    . GLY B 2 110  ? 202.167 354.003 225.697 1.00 91.05  ? 110  GLY C CA    1 
ATOM   8503  C C     . GLY B 2 110  ? 201.392 354.636 224.556 1.00 91.05  ? 110  GLY C C     1 
ATOM   8504  O O     . GLY B 2 110  ? 201.848 355.556 223.874 1.00 91.05  ? 110  GLY C O     1 
ATOM   8505  N N     . GLU B 2 111  ? 200.185 354.116 224.353 1.00 89.63  ? 111  GLU C N     1 
ATOM   8506  C CA    . GLU B 2 111  ? 199.324 354.586 223.279 1.00 89.63  ? 111  GLU C CA    1 
ATOM   8507  C C     . GLU B 2 111  ? 198.749 355.961 223.606 1.00 89.63  ? 111  GLU C C     1 
ATOM   8508  O O     . GLU B 2 111  ? 198.828 356.449 224.738 1.00 89.63  ? 111  GLU C O     1 
ATOM   8509  C CB    . GLU B 2 111  ? 198.190 353.592 223.029 1.00 89.63  ? 111  GLU C CB    1 
ATOM   8510  N N     . LEU B 2 112  ? 198.162 356.591 222.585 1.00 87.01  ? 112  LEU C N     1 
ATOM   8511  C CA    . LEU B 2 112  ? 197.556 357.904 222.777 1.00 87.01  ? 112  LEU C CA    1 
ATOM   8512  C C     . LEU B 2 112  ? 196.340 357.832 223.691 1.00 87.01  ? 112  LEU C C     1 
ATOM   8513  O O     . LEU B 2 112  ? 196.006 358.819 224.354 1.00 87.01  ? 112  LEU C O     1 
ATOM   8514  C CB    . LEU B 2 112  ? 197.173 358.513 221.427 1.00 87.01  ? 112  LEU C CB    1 
ATOM   8515  C CG    . LEU B 2 112  ? 196.736 359.979 221.430 1.00 87.01  ? 112  LEU C CG    1 
ATOM   8516  C CD1   . LEU B 2 112  ? 197.902 360.886 221.794 1.00 87.01  ? 112  LEU C CD1   1 
ATOM   8517  C CD2   . LEU B 2 112  ? 196.148 360.370 220.083 1.00 87.01  ? 112  LEU C CD2   1 
ATOM   8518  N N     . PHE B 2 113  ? 195.668 356.680 223.738 1.00 89.09  ? 113  PHE C N     1 
ATOM   8519  C CA    . PHE B 2 113  ? 194.504 356.533 224.608 1.00 89.09  ? 113  PHE C CA    1 
ATOM   8520  C C     . PHE B 2 113  ? 194.894 356.671 226.075 1.00 89.09  ? 113  PHE C C     1 
ATOM   8521  O O     . PHE B 2 113  ? 194.202 357.338 226.855 1.00 89.09  ? 113  PHE C O     1 
ATOM   8522  C CB    . PHE B 2 113  ? 193.830 355.185 224.351 1.00 89.09  ? 113  PHE C CB    1 
ATOM   8523  C CG    . PHE B 2 113  ? 192.355 355.180 224.633 1.00 89.09  ? 113  PHE C CG    1 
ATOM   8524  C CD1   . PHE B 2 113  ? 191.609 356.341 224.513 1.00 89.09  ? 113  PHE C CD1   1 
ATOM   8525  C CD2   . PHE B 2 113  ? 191.714 354.014 225.016 1.00 89.09  ? 113  PHE C CD2   1 
ATOM   8526  C CE1   . PHE B 2 113  ? 190.251 356.339 224.771 1.00 89.09  ? 113  PHE C CE1   1 
ATOM   8527  C CE2   . PHE B 2 113  ? 190.356 354.005 225.276 1.00 89.09  ? 113  PHE C CE2   1 
ATOM   8528  C CZ    . PHE B 2 113  ? 189.624 355.169 225.153 1.00 89.09  ? 113  PHE C CZ    1 
ATOM   8529  N N     . ASP B 2 114  ? 196.006 356.044 226.470 1.00 95.31  ? 114  ASP C N     1 
ATOM   8530  C CA    . ASP B 2 114  ? 196.441 356.113 227.862 1.00 95.31  ? 114  ASP C CA    1 
ATOM   8531  C C     . ASP B 2 114  ? 196.819 357.535 228.256 1.00 95.31  ? 114  ASP C C     1 
ATOM   8532  O O     . ASP B 2 114  ? 196.427 358.016 229.326 1.00 95.31  ? 114  ASP C O     1 
ATOM   8533  C CB    . ASP B 2 114  ? 197.616 355.162 228.091 1.00 95.31  ? 114  ASP C CB    1 
ATOM   8534  C CG    . ASP B 2 114  ? 197.261 353.717 227.802 1.00 95.31  ? 114  ASP C CG    1 
ATOM   8535  O OD1   . ASP B 2 114  ? 196.066 353.429 227.581 1.00 95.31  ? 114  ASP C OD1   1 
ATOM   8536  O OD2   . ASP B 2 114  ? 198.178 352.869 227.794 1.00 95.31  ? 114  ASP C OD2   1 
ATOM   8537  N N     . TYR B 2 115  ? 197.575 358.228 227.402 1.00 95.60  ? 115  TYR C N     1 
ATOM   8538  C CA    . TYR B 2 115  ? 197.949 359.607 227.703 1.00 95.60  ? 115  TYR C CA    1 
ATOM   8539  C C     . TYR B 2 115  ? 196.724 360.511 227.736 1.00 95.60  ? 115  TYR C C     1 
ATOM   8540  O O     . TYR B 2 115  ? 196.626 361.409 228.581 1.00 95.60  ? 115  TYR C O     1 
ATOM   8541  C CB    . TYR B 2 115  ? 198.965 360.108 226.677 1.00 95.60  ? 115  TYR C CB    1 
ATOM   8542  C CG    . TYR B 2 115  ? 199.575 361.449 227.018 1.00 95.60  ? 115  TYR C CG    1 
ATOM   8543  C CD1   . TYR B 2 115  ? 200.444 361.584 228.093 1.00 95.60  ? 115  TYR C CD1   1 
ATOM   8544  C CD2   . TYR B 2 115  ? 199.287 362.578 226.263 1.00 95.60  ? 115  TYR C CD2   1 
ATOM   8545  C CE1   . TYR B 2 115  ? 201.006 362.806 228.409 1.00 95.60  ? 115  TYR C CE1   1 
ATOM   8546  C CE2   . TYR B 2 115  ? 199.844 363.805 226.572 1.00 95.60  ? 115  TYR C CE2   1 
ATOM   8547  C CZ    . TYR B 2 115  ? 200.703 363.913 227.646 1.00 95.60  ? 115  TYR C CZ    1 
ATOM   8548  O OH    . TYR B 2 115  ? 201.260 365.132 227.956 1.00 95.60  ? 115  TYR C OH    1 
ATOM   8549  N N     . LEU B 2 116  ? 195.778 360.288 226.820 1.00 87.85  ? 116  LEU C N     1 
ATOM   8550  C CA    . LEU B 2 116  ? 194.559 361.087 226.790 1.00 87.85  ? 116  LEU C CA    1 
ATOM   8551  C C     . LEU B 2 116  ? 193.735 360.893 228.057 1.00 87.85  ? 116  LEU C C     1 
ATOM   8552  O O     . LEU B 2 116  ? 193.211 361.862 228.618 1.00 87.85  ? 116  LEU C O     1 
ATOM   8553  C CB    . LEU B 2 116  ? 193.734 360.732 225.553 1.00 87.85  ? 116  LEU C CB    1 
ATOM   8554  C CG    . LEU B 2 116  ? 192.530 361.619 225.228 1.00 87.85  ? 116  LEU C CG    1 
ATOM   8555  C CD1   . LEU B 2 116  ? 192.918 363.088 225.223 1.00 87.85  ? 116  LEU C CD1   1 
ATOM   8556  C CD2   . LEU B 2 116  ? 191.914 361.219 223.895 1.00 87.85  ? 116  LEU C CD2   1 
ATOM   8557  N N     . THR B 2 117  ? 193.605 359.648 228.524 1.00 90.21  ? 117  THR C N     1 
ATOM   8558  C CA    . THR B 2 117  ? 192.811 359.407 229.725 1.00 90.21  ? 117  THR C CA    1 
ATOM   8559  C C     . THR B 2 117  ? 193.557 359.843 230.981 1.00 90.21  ? 117  THR C C     1 
ATOM   8560  O O     . THR B 2 117  ? 192.932 360.143 232.006 1.00 90.21  ? 117  THR C O     1 
ATOM   8561  C CB    . THR B 2 117  ? 192.401 357.934 229.811 1.00 90.21  ? 117  THR C CB    1 
ATOM   8562  O OG1   . THR B 2 117  ? 191.343 357.789 230.768 1.00 90.21  ? 117  THR C OG1   1 
ATOM   8563  C CG2   . THR B 2 117  ? 193.571 357.057 230.228 1.00 90.21  ? 117  THR C CG2   1 
ATOM   8564  N N     . GLU B 2 118  ? 194.891 359.886 230.927 1.00 97.45  ? 118  GLU C N     1 
ATOM   8565  C CA    . GLU B 2 118  ? 195.654 360.373 232.071 1.00 97.45  ? 118  GLU C CA    1 
ATOM   8566  C C     . GLU B 2 118  ? 195.574 361.891 232.187 1.00 97.45  ? 118  GLU C C     1 
ATOM   8567  O O     . GLU B 2 118  ? 195.409 362.426 233.290 1.00 97.45  ? 118  GLU C O     1 
ATOM   8568  C CB    . GLU B 2 118  ? 197.110 359.919 231.963 1.00 97.45  ? 118  GLU C CB    1 
ATOM   8569  C CG    . GLU B 2 118  ? 197.955 360.248 233.184 1.00 97.45  ? 118  GLU C CG    1 
ATOM   8570  C CD    . GLU B 2 118  ? 199.049 359.227 233.428 1.00 97.45  ? 118  GLU C CD    1 
ATOM   8571  O OE1   . GLU B 2 118  ? 199.281 358.379 232.541 1.00 97.45  ? 118  GLU C OE1   1 
ATOM   8572  O OE2   . GLU B 2 118  ? 199.677 359.274 234.506 1.00 97.45  ? 118  GLU C OE2   1 
ATOM   8573  N N     . LYS B 2 119  ? 195.688 362.599 231.066 1.00 91.91  ? 119  LYS C N     1 
ATOM   8574  C CA    . LYS B 2 119  ? 195.698 364.056 231.065 1.00 91.91  ? 119  LYS C CA    1 
ATOM   8575  C C     . LYS B 2 119  ? 194.336 364.668 230.763 1.00 91.91  ? 119  LYS C C     1 
ATOM   8576  O O     . LYS B 2 119  ? 194.227 365.899 230.727 1.00 91.91  ? 119  LYS C O     1 
ATOM   8577  C CB    . LYS B 2 119  ? 196.725 364.574 230.053 1.00 91.91  ? 119  LYS C CB    1 
ATOM   8578  C CG    . LYS B 2 119  ? 198.161 364.185 230.368 1.00 91.91  ? 119  LYS C CG    1 
ATOM   8579  C CD    . LYS B 2 119  ? 198.798 365.151 231.358 1.00 91.91  ? 119  LYS C CD    1 
ATOM   8580  C CE    . LYS B 2 119  ? 198.569 366.601 230.958 1.00 91.91  ? 119  LYS C CE    1 
ATOM   8581  N NZ    . LYS B 2 119  ? 198.998 366.876 229.558 1.00 91.91  ? 119  LYS C NZ    1 
ATOM   8582  N N     . VAL B 2 120  ? 193.310 363.847 230.530 1.00 89.87  ? 120  VAL C N     1 
ATOM   8583  C CA    . VAL B 2 120  ? 191.955 364.305 230.225 1.00 89.87  ? 120  VAL C CA    1 
ATOM   8584  C C     . VAL B 2 120  ? 191.964 365.122 228.938 1.00 89.87  ? 120  VAL C C     1 
ATOM   8585  O O     . VAL B 2 120  ? 191.428 364.689 227.912 1.00 89.87  ? 120  VAL C O     1 
ATOM   8586  C CB    . VAL B 2 120  ? 191.350 365.108 231.393 1.00 89.87  ? 120  VAL C CB    1 
ATOM   8587  C CG1   . VAL B 2 120  ? 190.020 365.725 230.984 1.00 89.87  ? 120  VAL C CG1   1 
ATOM   8588  C CG2   . VAL B 2 120  ? 191.180 364.219 232.615 1.00 89.87  ? 120  VAL C CG2   1 
ATOM   8589  N N     . THR B 2 121  ? 192.569 366.309 228.983 1.00 90.70  ? 121  THR C N     1 
ATOM   8590  C CA    . THR B 2 121  ? 192.682 367.181 227.823 1.00 90.70  ? 121  THR C CA    1 
ATOM   8591  C C     . THR B 2 121  ? 194.108 367.703 227.723 1.00 90.70  ? 121  THR C C     1 
ATOM   8592  O O     . THR B 2 121  ? 194.685 368.150 228.719 1.00 90.70  ? 121  THR C O     1 
ATOM   8593  C CB    . THR B 2 121  ? 191.695 368.355 227.909 1.00 90.70  ? 121  THR C CB    1 
ATOM   8594  O OG1   . THR B 2 121  ? 190.354 367.851 227.944 1.00 90.70  ? 121  THR C OG1   1 
ATOM   8595  C CG2   . THR B 2 121  ? 191.849 369.277 226.708 1.00 90.70  ? 121  THR C CG2   1 
ATOM   8596  N N     . LEU B 2 122  ? 194.670 367.647 226.520 1.00 97.49  ? 122  LEU C N     1 
ATOM   8597  C CA    . LEU B 2 122  ? 196.031 368.100 226.279 1.00 97.49  ? 122  LEU C CA    1 
ATOM   8598  C C     . LEU B 2 122  ? 196.067 369.606 226.033 1.00 97.49  ? 122  LEU C C     1 
ATOM   8599  O O     . LEU B 2 122  ? 195.036 370.260 225.857 1.00 97.49  ? 122  LEU C O     1 
ATOM   8600  C CB    . LEU B 2 122  ? 196.656 367.363 225.091 1.00 97.49  ? 122  LEU C CB    1 
ATOM   8601  C CG    . LEU B 2 122  ? 197.154 365.923 225.271 1.00 97.49  ? 122  LEU C CG    1 
ATOM   8602  C CD1   . LEU B 2 122  ? 196.026 364.946 225.569 1.00 97.49  ? 122  LEU C CD1   1 
ATOM   8603  C CD2   . LEU B 2 122  ? 197.934 365.480 224.042 1.00 97.49  ? 122  LEU C CD2   1 
ATOM   8604  N N     . SER B 2 123  ? 197.281 370.149 226.022 1.00 106.15 ? 123  SER C N     1 
ATOM   8605  C CA    . SER B 2 123  ? 197.473 371.575 225.814 1.00 106.15 ? 123  SER C CA    1 
ATOM   8606  C C     . SER B 2 123  ? 197.324 371.933 224.337 1.00 106.15 ? 123  SER C C     1 
ATOM   8607  O O     . SER B 2 123  ? 197.265 371.067 223.459 1.00 106.15 ? 123  SER C O     1 
ATOM   8608  C CB    . SER B 2 123  ? 198.847 372.011 226.324 1.00 106.15 ? 123  SER C CB    1 
ATOM   8609  O OG    . SER B 2 123  ? 199.830 371.882 225.312 1.00 106.15 ? 123  SER C OG    1 
ATOM   8610  N N     . GLU B 2 124  ? 197.257 373.241 224.073 1.00 108.81 ? 124  GLU C N     1 
ATOM   8611  C CA    . GLU B 2 124  ? 197.087 373.716 222.702 1.00 108.81 ? 124  GLU C CA    1 
ATOM   8612  C C     . GLU B 2 124  ? 198.294 373.368 221.838 1.00 108.81 ? 124  GLU C C     1 
ATOM   8613  O O     . GLU B 2 124  ? 198.141 372.975 220.676 1.00 108.81 ? 124  GLU C O     1 
ATOM   8614  C CB    . GLU B 2 124  ? 196.839 375.224 222.698 1.00 108.81 ? 124  GLU C CB    1 
ATOM   8615  C CG    . GLU B 2 124  ? 195.561 375.653 223.409 1.00 108.81 ? 124  GLU C CG    1 
ATOM   8616  C CD    . GLU B 2 124  ? 194.330 375.569 222.523 1.00 108.81 ? 124  GLU C CD    1 
ATOM   8617  O OE1   . GLU B 2 124  ? 194.159 374.549 221.822 1.00 108.81 ? 124  GLU C OE1   1 
ATOM   8618  O OE2   . GLU B 2 124  ? 193.531 376.529 222.528 1.00 108.81 ? 124  GLU C OE2   1 
ATOM   8619  N N     . LYS B 2 125  ? 199.504 373.519 222.381 1.00 109.92 ? 125  LYS C N     1 
ATOM   8620  C CA    . LYS B 2 125  ? 200.699 373.173 221.618 1.00 109.92 ? 125  LYS C CA    1 
ATOM   8621  C C     . LYS B 2 125  ? 200.743 371.682 221.305 1.00 109.92 ? 125  LYS C C     1 
ATOM   8622  O O     . LYS B 2 125  ? 201.107 371.282 220.192 1.00 109.92 ? 125  LYS C O     1 
ATOM   8623  C CB    . LYS B 2 125  ? 201.952 373.599 222.384 1.00 109.92 ? 125  LYS C CB    1 
ATOM   8624  N N     . GLU B 2 126  ? 200.374 370.845 222.278 1.00 112.05 ? 126  GLU C N     1 
ATOM   8625  C CA    . GLU B 2 126  ? 200.400 369.401 222.069 1.00 112.05 ? 126  GLU C CA    1 
ATOM   8626  C C     . GLU B 2 126  ? 199.422 368.986 220.976 1.00 112.05 ? 126  GLU C C     1 
ATOM   8627  O O     . GLU B 2 126  ? 199.771 368.215 220.075 1.00 112.05 ? 126  GLU C O     1 
ATOM   8628  C CB    . GLU B 2 126  ? 200.086 368.677 223.379 1.00 112.05 ? 126  GLU C CB    1 
ATOM   8629  N N     . THR B 2 127  ? 198.189 369.496 221.033 1.00 110.96 ? 127  THR C N     1 
ATOM   8630  C CA    . THR B 2 127  ? 197.210 369.129 220.015 1.00 110.96 ? 127  THR C CA    1 
ATOM   8631  C C     . THR B 2 127  ? 197.586 369.712 218.659 1.00 110.96 ? 127  THR C C     1 
ATOM   8632  O O     . THR B 2 127  ? 197.355 369.081 217.623 1.00 110.96 ? 127  THR C O     1 
ATOM   8633  C CB    . THR B 2 127  ? 195.800 369.565 220.431 1.00 110.96 ? 127  THR C CB    1 
ATOM   8634  O OG1   . THR B 2 127  ? 194.853 369.120 219.452 1.00 110.96 ? 127  THR C OG1   1 
ATOM   8635  C CG2   . THR B 2 127  ? 195.697 371.073 220.573 1.00 110.96 ? 127  THR C CG2   1 
ATOM   8636  N N     . ARG B 2 128  ? 198.193 370.903 218.643 1.00 110.38 ? 128  ARG C N     1 
ATOM   8637  C CA    . ARG B 2 128  ? 198.635 371.486 217.379 1.00 110.38 ? 128  ARG C CA    1 
ATOM   8638  C C     . ARG B 2 128  ? 199.716 370.633 216.726 1.00 110.38 ? 128  ARG C C     1 
ATOM   8639  O O     . ARG B 2 128  ? 199.650 370.346 215.524 1.00 110.38 ? 128  ARG C O     1 
ATOM   8640  C CB    . ARG B 2 128  ? 199.131 372.915 217.610 1.00 110.38 ? 128  ARG C CB    1 
ATOM   8641  C CG    . ARG B 2 128  ? 199.959 373.502 216.471 1.00 110.38 ? 128  ARG C CG    1 
ATOM   8642  C CD    . ARG B 2 128  ? 201.451 373.461 216.775 1.00 110.38 ? 128  ARG C CD    1 
ATOM   8643  N NE    . ARG B 2 128  ? 201.785 374.217 217.977 1.00 110.38 ? 128  ARG C NE    1 
ATOM   8644  C CZ    . ARG B 2 128  ? 202.098 375.505 217.989 1.00 110.38 ? 128  ARG C CZ    1 
ATOM   8645  N NH1   . ARG B 2 128  ? 202.130 376.219 216.875 1.00 110.38 ? 128  ARG C NH1   1 
ATOM   8646  N NH2   . ARG B 2 128  ? 202.387 376.092 219.147 1.00 110.38 ? 128  ARG C NH2   1 
ATOM   8647  N N     . LYS B 2 129  ? 200.716 370.208 217.503 1.00 111.14 ? 129  LYS C N     1 
ATOM   8648  C CA    . LYS B 2 129  ? 201.789 369.399 216.931 1.00 111.14 ? 129  LYS C CA    1 
ATOM   8649  C C     . LYS B 2 129  ? 201.288 368.011 216.543 1.00 111.14 ? 129  LYS C C     1 
ATOM   8650  O O     . LYS B 2 129  ? 201.721 367.450 215.528 1.00 111.14 ? 129  LYS C O     1 
ATOM   8651  C CB    . LYS B 2 129  ? 202.969 369.316 217.904 1.00 111.14 ? 129  LYS C CB    1 
ATOM   8652  C CG    . LYS B 2 129  ? 202.738 368.467 219.140 1.00 111.14 ? 129  LYS C CG    1 
ATOM   8653  C CD    . LYS B 2 129  ? 203.989 368.390 219.998 1.00 111.14 ? 129  LYS C CD    1 
ATOM   8654  C CE    . LYS B 2 129  ? 203.910 367.235 220.982 1.00 111.14 ? 129  LYS C CE    1 
ATOM   8655  N NZ    . LYS B 2 129  ? 203.068 366.123 220.461 1.00 111.14 ? 129  LYS C NZ    1 
ATOM   8656  N N     . ILE B 2 130  ? 200.355 367.451 217.320 1.00 109.67 ? 130  ILE C N     1 
ATOM   8657  C CA    . ILE B 2 130  ? 199.768 366.163 216.961 1.00 109.67 ? 130  ILE C CA    1 
ATOM   8658  C C     . ILE B 2 130  ? 198.997 366.279 215.653 1.00 109.67 ? 130  ILE C C     1 
ATOM   8659  O O     . ILE B 2 130  ? 199.103 365.416 214.771 1.00 109.67 ? 130  ILE C O     1 
ATOM   8660  C CB    . ILE B 2 130  ? 198.874 365.648 218.106 1.00 109.67 ? 130  ILE C CB    1 
ATOM   8661  C CG1   . ILE B 2 130  ? 199.725 364.999 219.198 1.00 109.67 ? 130  ILE C CG1   1 
ATOM   8662  C CG2   . ILE B 2 130  ? 197.838 364.662 217.583 1.00 109.67 ? 130  ILE C CG2   1 
ATOM   8663  C CD1   . ILE B 2 130  ? 199.053 364.961 220.551 1.00 109.67 ? 130  ILE C CD1   1 
ATOM   8664  N N     . MET B 2 131  ? 198.213 367.350 215.506 1.00 109.73 ? 131  MET C N     1 
ATOM   8665  C CA    . MET B 2 131  ? 197.462 367.565 214.277 1.00 109.73 ? 131  MET C CA    1 
ATOM   8666  C C     . MET B 2 131  ? 198.396 367.744 213.090 1.00 109.73 ? 131  MET C C     1 
ATOM   8667  O O     . MET B 2 131  ? 198.144 367.205 212.008 1.00 109.73 ? 131  MET C O     1 
ATOM   8668  C CB    . MET B 2 131  ? 196.557 368.787 214.431 1.00 109.73 ? 131  MET C CB    1 
ATOM   8669  C CG    . MET B 2 131  ? 195.171 368.617 213.846 1.00 109.73 ? 131  MET C CG    1 
ATOM   8670  S SD    . MET B 2 131  ? 194.152 367.574 214.904 1.00 109.73 ? 131  MET C SD    1 
ATOM   8671  C CE    . MET B 2 131  ? 193.978 368.637 216.335 1.00 109.73 ? 131  MET C CE    1 
ATOM   8672  N N     . ARG B 2 132  ? 199.482 368.500 213.275 1.00 111.51 ? 132  ARG C N     1 
ATOM   8673  C CA    . ARG B 2 132  ? 200.439 368.696 212.190 1.00 111.51 ? 132  ARG C CA    1 
ATOM   8674  C C     . ARG B 2 132  ? 201.085 367.380 211.777 1.00 111.51 ? 132  ARG C C     1 
ATOM   8675  O O     . ARG B 2 132  ? 201.202 367.085 210.581 1.00 111.51 ? 132  ARG C O     1 
ATOM   8676  C CB    . ARG B 2 132  ? 201.503 369.709 212.611 1.00 111.51 ? 132  ARG C CB    1 
ATOM   8677  C CG    . ARG B 2 132  ? 202.138 370.466 211.456 1.00 111.51 ? 132  ARG C CG    1 
ATOM   8678  C CD    . ARG B 2 132  ? 203.206 371.426 211.954 1.00 111.51 ? 132  ARG C CD    1 
ATOM   8679  N NE    . ARG B 2 132  ? 202.662 372.752 212.221 1.00 111.51 ? 132  ARG C NE    1 
ATOM   8680  C CZ    . ARG B 2 132  ? 203.107 373.568 213.167 1.00 111.51 ? 132  ARG C CZ    1 
ATOM   8681  N NH1   . ARG B 2 132  ? 204.106 373.224 213.963 1.00 111.51 ? 132  ARG C NH1   1 
ATOM   8682  N NH2   . ARG B 2 132  ? 202.534 374.758 213.320 1.00 111.51 ? 132  ARG C NH2   1 
ATOM   8683  N N     . ALA B 2 133  ? 201.502 366.569 212.754 1.00 104.22 ? 133  ALA C N     1 
ATOM   8684  C CA    . ALA B 2 133  ? 202.120 365.286 212.435 1.00 104.22 ? 133  ALA C CA    1 
ATOM   8685  C C     . ALA B 2 133  ? 201.141 364.359 211.725 1.00 104.22 ? 133  ALA C C     1 
ATOM   8686  O O     . ALA B 2 133  ? 201.502 363.695 210.745 1.00 104.22 ? 133  ALA C O     1 
ATOM   8687  C CB    . ALA B 2 133  ? 202.655 364.630 213.708 1.00 104.22 ? 133  ALA C CB    1 
ATOM   8688  N N     . LEU B 2 134  ? 199.894 364.304 212.199 1.00 102.76 ? 134  LEU C N     1 
ATOM   8689  C CA    . LEU B 2 134  ? 198.911 363.429 211.570 1.00 102.76 ? 134  LEU C CA    1 
ATOM   8690  C C     . LEU B 2 134  ? 198.577 363.901 210.159 1.00 102.76 ? 134  LEU C C     1 
ATOM   8691  O O     . LEU B 2 134  ? 198.422 363.084 209.244 1.00 102.76 ? 134  LEU C O     1 
ATOM   8692  C CB    . LEU B 2 134  ? 197.651 363.349 212.433 1.00 102.76 ? 134  LEU C CB    1 
ATOM   8693  C CG    . LEU B 2 134  ? 196.670 362.220 212.109 1.00 102.76 ? 134  LEU C CG    1 
ATOM   8694  C CD1   . LEU B 2 134  ? 196.058 361.664 213.386 1.00 102.76 ? 134  LEU C CD1   1 
ATOM   8695  C CD2   . LEU B 2 134  ? 195.584 362.690 211.160 1.00 102.76 ? 134  LEU C CD2   1 
ATOM   8696  N N     . LEU B 2 135  ? 198.464 365.218 209.962 1.00 100.51 ? 135  LEU C N     1 
ATOM   8697  C CA    . LEU B 2 135  ? 198.217 365.745 208.625 1.00 100.51 ? 135  LEU C CA    1 
ATOM   8698  C C     . LEU B 2 135  ? 199.370 365.419 207.688 1.00 100.51 ? 135  LEU C C     1 
ATOM   8699  O O     . LEU B 2 135  ? 199.150 365.064 206.524 1.00 100.51 ? 135  LEU C O     1 
ATOM   8700  C CB    . LEU B 2 135  ? 197.985 367.255 208.688 1.00 100.51 ? 135  LEU C CB    1 
ATOM   8701  C CG    . LEU B 2 135  ? 196.527 367.719 208.686 1.00 100.51 ? 135  LEU C CG    1 
ATOM   8702  C CD1   . LEU B 2 135  ? 195.893 367.438 207.335 1.00 100.51 ? 135  LEU C CD1   1 
ATOM   8703  C CD2   . LEU B 2 135  ? 195.732 367.060 209.802 1.00 100.51 ? 135  LEU C CD2   1 
ATOM   8704  N N     . GLU B 2 136  ? 200.608 365.536 208.180 1.00 99.55  ? 136  GLU C N     1 
ATOM   8705  C CA    . GLU B 2 136  ? 201.761 365.132 207.383 1.00 99.55  ? 136  GLU C CA    1 
ATOM   8706  C C     . GLU B 2 136  ? 201.673 363.658 207.012 1.00 99.55  ? 136  GLU C C     1 
ATOM   8707  O O     . GLU B 2 136  ? 201.950 363.278 205.866 1.00 99.55  ? 136  GLU C O     1 
ATOM   8708  C CB    . GLU B 2 136  ? 203.055 365.421 208.144 1.00 99.55  ? 136  GLU C CB    1 
ATOM   8709  N N     . VAL B 2 137  ? 201.274 362.819 207.972 1.00 100.32 ? 137  VAL C N     1 
ATOM   8710  C CA    . VAL B 2 137  ? 201.085 361.396 207.702 1.00 100.32 ? 137  VAL C CA    1 
ATOM   8711  C C     . VAL B 2 137  ? 200.094 361.198 206.563 1.00 100.32 ? 137  VAL C C     1 
ATOM   8712  O O     . VAL B 2 137  ? 200.348 360.434 205.623 1.00 100.32 ? 137  VAL C O     1 
ATOM   8713  C CB    . VAL B 2 137  ? 200.622 360.669 208.980 1.00 100.32 ? 137  VAL C CB    1 
ATOM   8714  C CG1   . VAL B 2 137  ? 199.790 359.439 208.633 1.00 100.32 ? 137  VAL C CG1   1 
ATOM   8715  C CG2   . VAL B 2 137  ? 201.806 360.286 209.839 1.00 100.32 ? 137  VAL C CG2   1 
ATOM   8716  N N     . ILE B 2 138  ? 198.951 361.887 206.626 1.00 100.18 ? 138  ILE C N     1 
ATOM   8717  C CA    . ILE B 2 138  ? 197.905 361.641 205.636 1.00 100.18 ? 138  ILE C CA    1 
ATOM   8718  C C     . ILE B 2 138  ? 198.319 362.149 204.257 1.00 100.18 ? 138  ILE C C     1 
ATOM   8719  O O     . ILE B 2 138  ? 198.036 361.497 203.246 1.00 100.18 ? 138  ILE C O     1 
ATOM   8720  C CB    . ILE B 2 138  ? 196.545 362.215 206.091 1.00 100.18 ? 138  ILE C CB    1 
ATOM   8721  C CG1   . ILE B 2 138  ? 196.420 363.714 205.806 1.00 100.18 ? 138  ILE C CG1   1 
ATOM   8722  C CG2   . ILE B 2 138  ? 196.251 361.857 207.543 1.00 100.18 ? 138  ILE C CG2   1 
ATOM   8723  C CD1   . ILE B 2 138  ? 195.004 364.226 205.899 1.00 100.18 ? 138  ILE C CD1   1 
ATOM   8724  N N     . CYS B 2 139  ? 199.009 363.295 204.174 1.00 101.59 ? 139  CYS C N     1 
ATOM   8725  C CA    . CYS B 2 139  ? 199.398 363.753 202.839 1.00 101.59 ? 139  CYS C CA    1 
ATOM   8726  C C     . CYS B 2 139  ? 200.494 362.866 202.261 1.00 101.59 ? 139  CYS C C     1 
ATOM   8727  O O     . CYS B 2 139  ? 200.492 362.576 201.058 1.00 101.59 ? 139  CYS C O     1 
ATOM   8728  C CB    . CYS B 2 139  ? 199.857 365.215 202.822 1.00 101.59 ? 139  CYS C CB    1 
ATOM   8729  S SG    . CYS B 2 139  ? 200.734 365.859 204.238 1.00 101.59 ? 139  CYS C SG    1 
ATOM   8730  N N     . THR B 2 140  ? 201.435 362.418 203.099 1.00 98.16  ? 140  THR C N     1 
ATOM   8731  C CA    . THR B 2 140  ? 202.469 361.510 202.617 1.00 98.16  ? 140  THR C CA    1 
ATOM   8732  C C     . THR B 2 140  ? 201.863 360.198 202.132 1.00 98.16  ? 140  THR C C     1 
ATOM   8733  O O     . THR B 2 140  ? 202.284 359.653 201.105 1.00 98.16  ? 140  THR C O     1 
ATOM   8734  C CB    . THR B 2 140  ? 203.500 361.252 203.717 1.00 98.16  ? 140  THR C CB    1 
ATOM   8735  O OG1   . THR B 2 140  ? 204.000 362.503 204.206 1.00 98.16  ? 140  THR C OG1   1 
ATOM   8736  C CG2   . THR B 2 140  ? 204.659 360.427 203.179 1.00 98.16  ? 140  THR C CG2   1 
ATOM   8737  N N     . LEU B 2 141  ? 200.873 359.675 202.860 1.00 98.15  ? 141  LEU C N     1 
ATOM   8738  C CA    . LEU B 2 141  ? 200.217 358.443 202.436 1.00 98.15  ? 141  LEU C CA    1 
ATOM   8739  C C     . LEU B 2 141  ? 199.415 358.650 201.156 1.00 98.15  ? 141  LEU C C     1 
ATOM   8740  O O     . LEU B 2 141  ? 199.401 357.779 200.278 1.00 98.15  ? 141  LEU C O     1 
ATOM   8741  C CB    . LEU B 2 141  ? 199.319 357.918 203.556 1.00 98.15  ? 141  LEU C CB    1 
ATOM   8742  C CG    . LEU B 2 141  ? 199.912 356.823 204.448 1.00 98.15  ? 141  LEU C CG    1 
ATOM   8743  C CD1   . LEU B 2 141  ? 198.809 356.017 205.118 1.00 98.15  ? 141  LEU C CD1   1 
ATOM   8744  C CD2   . LEU B 2 141  ? 200.845 355.915 203.659 1.00 98.15  ? 141  LEU C CD2   1 
ATOM   8745  N N     . HIS B 2 142  ? 198.738 359.795 201.032 1.00 98.97  ? 142  HIS C N     1 
ATOM   8746  C CA    . HIS B 2 142  ? 197.924 360.054 199.849 1.00 98.97  ? 142  HIS C CA    1 
ATOM   8747  C C     . HIS B 2 142  ? 198.793 360.260 198.615 1.00 98.97  ? 142  HIS C C     1 
ATOM   8748  O O     . HIS B 2 142  ? 198.381 359.932 197.495 1.00 98.97  ? 142  HIS C O     1 
ATOM   8749  C CB    . HIS B 2 142  ? 197.030 361.271 200.087 1.00 98.97  ? 142  HIS C CB    1 
ATOM   8750  C CG    . HIS B 2 142  ? 195.858 360.993 200.977 1.00 98.97  ? 142  HIS C CG    1 
ATOM   8751  N ND1   . HIS B 2 142  ? 195.787 361.446 202.276 1.00 98.97  ? 142  HIS C ND1   1 
ATOM   8752  C CD2   . HIS B 2 142  ? 194.714 360.304 200.756 1.00 98.97  ? 142  HIS C CD2   1 
ATOM   8753  C CE1   . HIS B 2 142  ? 194.648 361.052 202.817 1.00 98.97  ? 142  HIS C CE1   1 
ATOM   8754  N NE2   . HIS B 2 142  ? 193.978 360.357 201.915 1.00 98.97  ? 142  HIS C NE2   1 
ATOM   8755  N N     . LYS B 2 143  ? 199.996 360.813 198.796 1.00 98.67  ? 143  LYS C N     1 
ATOM   8756  C CA    . LYS B 2 143  ? 200.914 360.963 197.672 1.00 98.67  ? 143  LYS C CA    1 
ATOM   8757  C C     . LYS B 2 143  ? 201.303 359.611 197.088 1.00 98.67  ? 143  LYS C C     1 
ATOM   8758  O O     . LYS B 2 143  ? 201.575 359.507 195.887 1.00 98.67  ? 143  LYS C O     1 
ATOM   8759  C CB    . LYS B 2 143  ? 202.157 361.738 198.112 1.00 98.67  ? 143  LYS C CB    1 
ATOM   8760  C CG    . LYS B 2 143  ? 203.146 362.028 196.993 1.00 98.67  ? 143  LYS C CG    1 
ATOM   8761  C CD    . LYS B 2 143  ? 204.271 362.934 197.468 1.00 98.67  ? 143  LYS C CD    1 
ATOM   8762  C CE    . LYS B 2 143  ? 205.006 362.331 198.654 1.00 98.67  ? 143  LYS C CE    1 
ATOM   8763  N NZ    . LYS B 2 143  ? 206.480 362.508 198.542 1.00 98.67  ? 143  LYS C NZ    1 
ATOM   8764  N N     . LEU B 2 144  ? 201.324 358.567 197.915 1.00 97.68  ? 144  LEU C N     1 
ATOM   8765  C CA    . LEU B 2 144  ? 201.610 357.211 197.470 1.00 97.68  ? 144  LEU C CA    1 
ATOM   8766  C C     . LEU B 2 144  ? 200.343 356.401 197.219 1.00 97.68  ? 144  LEU C C     1 
ATOM   8767  O O     . LEU B 2 144  ? 200.429 355.188 196.999 1.00 97.68  ? 144  LEU C O     1 
ATOM   8768  C CB    . LEU B 2 144  ? 202.497 356.494 198.492 1.00 97.68  ? 144  LEU C CB    1 
ATOM   8769  C CG    . LEU B 2 144  ? 204.008 356.501 198.238 1.00 97.68  ? 144  LEU C CG    1 
ATOM   8770  C CD1   . LEU B 2 144  ? 204.524 357.909 197.975 1.00 97.68  ? 144  LEU C CD1   1 
ATOM   8771  C CD2   . LEU B 2 144  ? 204.749 355.866 199.406 1.00 97.68  ? 144  LEU C CD2   1 
ATOM   8772  N N     . ASN B 2 145  ? 199.175 357.046 197.251 1.00 103.26 ? 145  ASN C N     1 
ATOM   8773  C CA    . ASN B 2 145  ? 197.884 356.402 197.002 1.00 103.26 ? 145  ASN C CA    1 
ATOM   8774  C C     . ASN B 2 145  ? 197.638 355.257 197.989 1.00 103.26 ? 145  ASN C C     1 
ATOM   8775  O O     . ASN B 2 145  ? 197.452 354.098 197.613 1.00 103.26 ? 145  ASN C O     1 
ATOM   8776  C CB    . ASN B 2 145  ? 197.774 355.914 195.551 1.00 103.26 ? 145  ASN C CB    1 
ATOM   8777  C CG    . ASN B 2 145  ? 198.180 356.973 194.539 1.00 103.26 ? 145  ASN C CG    1 
ATOM   8778  O OD1   . ASN B 2 145  ? 199.368 357.229 194.340 1.00 103.26 ? 145  ASN C OD1   1 
ATOM   8779  N ND2   . ASN B 2 145  ? 197.197 357.612 193.916 1.00 103.26 ? 145  ASN C ND2   1 
ATOM   8780  N N     . ILE B 2 146  ? 197.643 355.609 199.273 1.00 100.49 ? 146  ILE C N     1 
ATOM   8781  C CA    . ILE B 2 146  ? 197.378 354.667 200.355 1.00 100.49 ? 146  ILE C CA    1 
ATOM   8782  C C     . ILE B 2 146  ? 196.416 355.321 201.335 1.00 100.49 ? 146  ILE C C     1 
ATOM   8783  O O     . ILE B 2 146  ? 196.635 356.462 201.758 1.00 100.49 ? 146  ILE C O     1 
ATOM   8784  C CB    . ILE B 2 146  ? 198.674 354.236 201.070 1.00 100.49 ? 146  ILE C CB    1 
ATOM   8785  C CG1   . ILE B 2 146  ? 199.514 353.338 200.158 1.00 100.49 ? 146  ILE C CG1   1 
ATOM   8786  C CG2   . ILE B 2 146  ? 198.357 353.515 202.371 1.00 100.49 ? 146  ILE C CG2   1 
ATOM   8787  C CD1   . ILE B 2 146  ? 201.002 353.433 200.411 1.00 100.49 ? 146  ILE C CD1   1 
ATOM   8788  N N     . VAL B 2 147  ? 195.354 354.603 201.695 1.00 101.16 ? 147  VAL C N     1 
ATOM   8789  C CA    . VAL B 2 147  ? 194.361 355.070 202.657 1.00 101.16 ? 147  VAL C CA    1 
ATOM   8790  C C     . VAL B 2 147  ? 194.311 354.076 203.811 1.00 101.16 ? 147  VAL C C     1 
ATOM   8791  O O     . VAL B 2 147  ? 194.455 352.865 203.604 1.00 101.16 ? 147  VAL C O     1 
ATOM   8792  C CB    . VAL B 2 147  ? 192.974 355.258 202.010 1.00 101.16 ? 147  VAL C CB    1 
ATOM   8793  C CG1   . VAL B 2 147  ? 193.100 356.028 200.704 1.00 101.16 ? 147  VAL C CG1   1 
ATOM   8794  C CG2   . VAL B 2 147  ? 192.289 353.920 201.768 1.00 101.16 ? 147  VAL C CG2   1 
ATOM   8795  N N     . HIS B 2 148  ? 194.149 354.595 205.028 1.00 98.72  ? 148  HIS C N     1 
ATOM   8796  C CA    . HIS B 2 148  ? 194.204 353.769 206.231 1.00 98.72  ? 148  HIS C CA    1 
ATOM   8797  C C     . HIS B 2 148  ? 192.812 353.376 206.723 1.00 98.72  ? 148  HIS C C     1 
ATOM   8798  O O     . HIS B 2 148  ? 192.590 352.229 207.122 1.00 98.72  ? 148  HIS C O     1 
ATOM   8799  C CB    . HIS B 2 148  ? 194.977 354.506 207.330 1.00 98.72  ? 148  HIS C CB    1 
ATOM   8800  C CG    . HIS B 2 148  ? 195.501 353.608 208.406 1.00 98.72  ? 148  HIS C CG    1 
ATOM   8801  N ND1   . HIS B 2 148  ? 194.749 353.243 209.501 1.00 98.72  ? 148  HIS C ND1   1 
ATOM   8802  C CD2   . HIS B 2 148  ? 196.697 352.992 208.549 1.00 98.72  ? 148  HIS C CD2   1 
ATOM   8803  C CE1   . HIS B 2 148  ? 195.462 352.447 210.277 1.00 98.72  ? 148  HIS C CE1   1 
ATOM   8804  N NE2   . HIS B 2 148  ? 196.649 352.278 209.722 1.00 98.72  ? 148  HIS C NE2   1 
ATOM   8805  N N     . ARG B 2 149  ? 191.869 354.320 206.699 1.00 104.82 ? 149  ARG C N     1 
ATOM   8806  C CA    . ARG B 2 149  ? 190.492 354.161 207.170 1.00 104.82 ? 149  ARG C CA    1 
ATOM   8807  C C     . ARG B 2 149  ? 190.399 353.697 208.619 1.00 104.82 ? 149  ARG C C     1 
ATOM   8808  O O     . ARG B 2 149  ? 189.322 353.268 209.053 1.00 104.82 ? 149  ARG C O     1 
ATOM   8809  C CB    . ARG B 2 149  ? 189.674 353.201 206.291 1.00 104.82 ? 149  ARG C CB    1 
ATOM   8810  C CG    . ARG B 2 149  ? 190.214 352.954 204.888 1.00 104.82 ? 149  ARG C CG    1 
ATOM   8811  C CD    . ARG B 2 149  ? 189.590 351.709 204.277 1.00 104.82 ? 149  ARG C CD    1 
ATOM   8812  N NE    . ARG B 2 149  ? 190.202 350.489 204.791 1.00 104.82 ? 149  ARG C NE    1 
ATOM   8813  C CZ    . ARG B 2 149  ? 189.846 349.263 204.433 1.00 104.82 ? 149  ARG C CZ    1 
ATOM   8814  N NH1   . ARG B 2 149  ? 188.878 349.052 203.557 1.00 104.82 ? 149  ARG C NH1   1 
ATOM   8815  N NH2   . ARG B 2 149  ? 190.477 348.222 204.970 1.00 104.82 ? 149  ARG C NH2   1 
ATOM   8816  N N     . ASP B 2 150  ? 191.488 353.767 209.384 1.00 99.03  ? 150  ASP C N     1 
ATOM   8817  C CA    . ASP B 2 150  ? 191.487 353.346 210.782 1.00 99.03  ? 150  ASP C CA    1 
ATOM   8818  C C     . ASP B 2 150  ? 192.232 354.355 211.644 1.00 99.03  ? 150  ASP C C     1 
ATOM   8819  O O     . ASP B 2 150  ? 193.059 353.991 212.486 1.00 99.03  ? 150  ASP C O     1 
ATOM   8820  C CB    . ASP B 2 150  ? 192.090 351.950 210.940 1.00 99.03  ? 150  ASP C CB    1 
ATOM   8821  C CG    . ASP B 2 150  ? 191.288 351.071 211.880 1.00 99.03  ? 150  ASP C CG    1 
ATOM   8822  O OD1   . ASP B 2 150  ? 190.052 351.237 211.941 1.00 99.03  ? 150  ASP C OD1   1 
ATOM   8823  O OD2   . ASP B 2 150  ? 191.894 350.215 212.558 1.00 99.03  ? 150  ASP C OD2   1 
ATOM   8824  N N     . LEU B 2 151  ? 191.949 355.640 211.445 1.00 93.88  ? 151  LEU C N     1 
ATOM   8825  C CA    . LEU B 2 151  ? 192.580 356.712 212.214 1.00 93.88  ? 151  LEU C CA    1 
ATOM   8826  C C     . LEU B 2 151  ? 191.869 356.815 213.558 1.00 93.88  ? 151  LEU C C     1 
ATOM   8827  O O     . LEU B 2 151  ? 190.836 357.479 213.679 1.00 93.88  ? 151  LEU C O     1 
ATOM   8828  C CB    . LEU B 2 151  ? 192.523 358.028 211.448 1.00 93.88  ? 151  LEU C CB    1 
ATOM   8829  C CG    . LEU B 2 151  ? 193.721 358.402 210.574 1.00 93.88  ? 151  LEU C CG    1 
ATOM   8830  C CD1   . LEU B 2 151  ? 193.553 359.807 210.020 1.00 93.88  ? 151  LEU C CD1   1 
ATOM   8831  C CD2   . LEU B 2 151  ? 195.008 358.296 211.368 1.00 93.88  ? 151  LEU C CD2   1 
ATOM   8832  N N     . LYS B 2 152  ? 192.421 356.158 214.568 1.00 87.22  ? 152  LYS C N     1 
ATOM   8833  C CA    . LYS B 2 152  ? 191.860 356.115 215.908 1.00 87.22  ? 152  LYS C CA    1 
ATOM   8834  C C     . LYS B 2 152  ? 192.951 356.407 216.924 1.00 87.22  ? 152  LYS C C     1 
ATOM   8835  O O     . LYS B 2 152  ? 194.132 356.144 216.670 1.00 87.22  ? 152  LYS C O     1 
ATOM   8836  C CB    . LYS B 2 152  ? 191.230 354.743 216.195 1.00 87.22  ? 152  LYS C CB    1 
ATOM   8837  N N     . PRO B 2 153  ? 192.592 356.963 218.086 1.00 84.33  ? 153  PRO C N     1 
ATOM   8838  C CA    . PRO B 2 153  ? 193.612 357.201 219.121 1.00 84.33  ? 153  PRO C CA    1 
ATOM   8839  C C     . PRO B 2 153  ? 194.277 355.925 219.600 1.00 84.33  ? 153  PRO C C     1 
ATOM   8840  O O     . PRO B 2 153  ? 195.445 355.955 220.006 1.00 84.33  ? 153  PRO C O     1 
ATOM   8841  C CB    . PRO B 2 153  ? 192.822 357.887 220.247 1.00 84.33  ? 153  PRO C CB    1 
ATOM   8842  C CG    . PRO B 2 153  ? 191.532 358.330 219.620 1.00 84.33  ? 153  PRO C CG    1 
ATOM   8843  C CD    . PRO B 2 153  ? 191.245 357.330 218.551 1.00 84.33  ? 153  PRO C CD    1 
ATOM   8844  N N     . GLU B 2 154  ? 193.555 354.803 219.568 1.00 87.60  ? 154  GLU C N     1 
ATOM   8845  C CA    . GLU B 2 154  ? 194.128 353.528 219.982 1.00 87.60  ? 154  GLU C CA    1 
ATOM   8846  C C     . GLU B 2 154  ? 195.262 353.097 219.062 1.00 87.60  ? 154  GLU C C     1 
ATOM   8847  O O     . GLU B 2 154  ? 196.223 352.463 219.514 1.00 87.60  ? 154  GLU C O     1 
ATOM   8848  C CB    . GLU B 2 154  ? 193.033 352.464 220.015 1.00 87.60  ? 154  GLU C CB    1 
ATOM   8849  C CG    . GLU B 2 154  ? 191.636 353.049 220.153 1.00 87.60  ? 154  GLU C CG    1 
ATOM   8850  C CD    . GLU B 2 154  ? 190.548 352.001 220.071 1.00 87.60  ? 154  GLU C CD    1 
ATOM   8851  O OE1   . GLU B 2 154  ? 190.201 351.424 221.121 1.00 87.60  ? 154  GLU C OE1   1 
ATOM   8852  O OE2   . GLU B 2 154  ? 190.039 351.756 218.958 1.00 87.60  ? 154  GLU C OE2   1 
ATOM   8853  N N     . ASN B 2 155  ? 195.172 353.430 217.777 1.00 84.26  ? 155  ASN C N     1 
ATOM   8854  C CA    . ASN B 2 155  ? 196.199 353.088 216.803 1.00 84.26  ? 155  ASN C CA    1 
ATOM   8855  C C     . ASN B 2 155  ? 197.341 354.094 216.769 1.00 84.26  ? 155  ASN C C     1 
ATOM   8856  O O     . ASN B 2 155  ? 198.296 353.901 216.009 1.00 84.26  ? 155  ASN C O     1 
ATOM   8857  C CB    . ASN B 2 155  ? 195.579 352.968 215.407 1.00 84.26  ? 155  ASN C CB    1 
ATOM   8858  C CG    . ASN B 2 155  ? 195.082 351.569 215.109 1.00 84.26  ? 155  ASN C CG    1 
ATOM   8859  O OD1   . ASN B 2 155  ? 195.485 350.604 215.757 1.00 84.26  ? 155  ASN C OD1   1 
ATOM   8860  N ND2   . ASN B 2 155  ? 194.200 351.451 214.123 1.00 84.26  ? 155  ASN C ND2   1 
ATOM   8861  N N     . ILE B 2 156  ? 197.268 355.154 217.569 1.00 83.97  ? 156  ILE C N     1 
ATOM   8862  C CA    . ILE B 2 156  ? 198.295 356.187 217.626 1.00 83.97  ? 156  ILE C CA    1 
ATOM   8863  C C     . ILE B 2 156  ? 199.028 356.058 218.954 1.00 83.97  ? 156  ILE C C     1 
ATOM   8864  O O     . ILE B 2 156  ? 198.395 355.955 220.012 1.00 83.97  ? 156  ILE C O     1 
ATOM   8865  C CB    . ILE B 2 156  ? 197.690 357.593 217.463 1.00 83.97  ? 156  ILE C CB    1 
ATOM   8866  C CG1   . ILE B 2 156  ? 197.061 357.746 216.076 1.00 83.97  ? 156  ILE C CG1   1 
ATOM   8867  C CG2   . ILE B 2 156  ? 198.746 358.662 217.693 1.00 83.97  ? 156  ILE C CG2   1 
ATOM   8868  C CD1   . ILE B 2 156  ? 195.989 358.810 216.007 1.00 83.97  ? 156  ILE C CD1   1 
ATOM   8869  N N     . LEU B 2 157  ? 200.355 356.048 218.897 1.00 88.34  ? 157  LEU C N     1 
ATOM   8870  C CA    . LEU B 2 157  ? 201.201 355.931 220.074 1.00 88.34  ? 157  LEU C CA    1 
ATOM   8871  C C     . LEU B 2 157  ? 202.063 357.183 220.217 1.00 88.34  ? 157  LEU C C     1 
ATOM   8872  O O     . LEU B 2 157  ? 202.017 358.098 219.392 1.00 88.34  ? 157  LEU C O     1 
ATOM   8873  C CB    . LEU B 2 157  ? 202.065 354.671 219.987 1.00 88.34  ? 157  LEU C CB    1 
ATOM   8874  C CG    . LEU B 2 157  ? 201.452 353.439 219.316 1.00 88.34  ? 157  LEU C CG    1 
ATOM   8875  C CD1   . LEU B 2 157  ? 202.501 352.353 219.134 1.00 88.34  ? 157  LEU C CD1   1 
ATOM   8876  C CD2   . LEU B 2 157  ? 200.269 352.912 220.111 1.00 88.34  ? 157  LEU C CD2   1 
ATOM   8877  N N     . LEU B 2 158  ? 202.858 357.217 221.286 1.00 98.39  ? 158  LEU C N     1 
ATOM   8878  C CA    . LEU B 2 158  ? 203.784 358.314 221.530 1.00 98.39  ? 158  LEU C CA    1 
ATOM   8879  C C     . LEU B 2 158  ? 205.119 357.748 221.989 1.00 98.39  ? 158  LEU C C     1 
ATOM   8880  O O     . LEU B 2 158  ? 205.202 356.623 222.487 1.00 98.39  ? 158  LEU C O     1 
ATOM   8881  C CB    . LEU B 2 158  ? 203.259 359.308 222.579 1.00 98.39  ? 158  LEU C CB    1 
ATOM   8882  C CG    . LEU B 2 158  ? 201.782 359.707 222.579 1.00 98.39  ? 158  LEU C CG    1 
ATOM   8883  C CD1   . LEU B 2 158  ? 200.973 358.750 223.437 1.00 98.39  ? 158  LEU C CD1   1 
ATOM   8884  C CD2   . LEU B 2 158  ? 201.612 361.140 223.061 1.00 98.39  ? 158  LEU C CD2   1 
ATOM   8885  N N     . ASP B 2 159  ? 206.165 358.547 221.822 1.00 108.73 ? 159  ASP C N     1 
ATOM   8886  C CA    . ASP B 2 159  ? 207.516 358.185 222.226 1.00 108.73 ? 159  ASP C CA    1 
ATOM   8887  C C     . ASP B 2 159  ? 208.022 359.189 223.263 1.00 108.73 ? 159  ASP C C     1 
ATOM   8888  O O     . ASP B 2 159  ? 207.277 360.046 223.746 1.00 108.73 ? 159  ASP C O     1 
ATOM   8889  C CB    . ASP B 2 159  ? 208.440 358.110 221.007 1.00 108.73 ? 159  ASP C CB    1 
ATOM   8890  C CG    . ASP B 2 159  ? 208.241 359.269 220.049 1.00 108.73 ? 159  ASP C CG    1 
ATOM   8891  O OD1   . ASP B 2 159  ? 207.736 360.326 220.484 1.00 108.73 ? 159  ASP C OD1   1 
ATOM   8892  O OD2   . ASP B 2 159  ? 208.590 359.124 218.859 1.00 108.73 ? 159  ASP C OD2   1 
ATOM   8893  N N     . ASP B 2 160  ? 209.307 359.070 223.607 1.00 116.24 ? 160  ASP C N     1 
ATOM   8894  C CA    . ASP B 2 160  ? 209.906 359.976 224.581 1.00 116.24 ? 160  ASP C CA    1 
ATOM   8895  C C     . ASP B 2 160  ? 209.958 361.413 224.081 1.00 116.24 ? 160  ASP C C     1 
ATOM   8896  O O     . ASP B 2 160  ? 210.034 362.339 224.896 1.00 116.24 ? 160  ASP C O     1 
ATOM   8897  C CB    . ASP B 2 160  ? 211.314 359.499 224.943 1.00 116.24 ? 160  ASP C CB    1 
ATOM   8898  C CG    . ASP B 2 160  ? 211.311 358.154 225.641 1.00 116.24 ? 160  ASP C CG    1 
ATOM   8899  O OD1   . ASP B 2 160  ? 210.248 357.498 225.666 1.00 116.24 ? 160  ASP C OD1   1 
ATOM   8900  O OD2   . ASP B 2 160  ? 212.372 357.751 226.164 1.00 116.24 ? 160  ASP C OD2   1 
ATOM   8901  N N     . ASN B 2 161  ? 209.920 361.621 222.767 1.00 114.43 ? 161  ASN C N     1 
ATOM   8902  C CA    . ASN B 2 161  ? 209.945 362.954 222.182 1.00 114.43 ? 161  ASN C CA    1 
ATOM   8903  C C     . ASN B 2 161  ? 208.552 363.522 221.944 1.00 114.43 ? 161  ASN C C     1 
ATOM   8904  O O     . ASN B 2 161  ? 208.431 364.572 221.303 1.00 114.43 ? 161  ASN C O     1 
ATOM   8905  C CB    . ASN B 2 161  ? 210.725 362.938 220.864 1.00 114.43 ? 161  ASN C CB    1 
ATOM   8906  N N     . MET B 2 162  ? 207.507 362.852 222.437 1.00 109.25 ? 162  MET C N     1 
ATOM   8907  C CA    . MET B 2 162  ? 206.118 363.275 222.244 1.00 109.25 ? 162  MET C CA    1 
ATOM   8908  C C     . MET B 2 162  ? 205.764 363.369 220.760 1.00 109.25 ? 162  MET C C     1 
ATOM   8909  O O     . MET B 2 162  ? 205.012 364.250 220.341 1.00 109.25 ? 162  MET C O     1 
ATOM   8910  C CB    . MET B 2 162  ? 205.830 364.600 222.957 1.00 109.25 ? 162  MET C CB    1 
ATOM   8911  C CG    . MET B 2 162  ? 205.957 364.533 224.471 1.00 109.25 ? 162  MET C CG    1 
ATOM   8912  S SD    . MET B 2 162  ? 205.767 362.860 225.116 1.00 109.25 ? 162  MET C SD    1 
ATOM   8913  C CE    . MET B 2 162  ? 206.970 362.869 226.442 1.00 109.25 ? 162  MET C CE    1 
ATOM   8914  N N     . ASN B 2 163  ? 206.308 362.455 219.963 1.00 101.08 ? 163  ASN C N     1 
ATOM   8915  C CA    . ASN B 2 163  ? 206.027 362.377 218.536 1.00 101.08 ? 163  ASN C CA    1 
ATOM   8916  C C     . ASN B 2 163  ? 205.154 361.160 218.268 1.00 101.08 ? 163  ASN C C     1 
ATOM   8917  O O     . ASN B 2 163  ? 205.475 360.052 218.710 1.00 101.08 ? 163  ASN C O     1 
ATOM   8918  C CB    . ASN B 2 163  ? 207.324 362.297 217.725 1.00 101.08 ? 163  ASN C CB    1 
ATOM   8919  C CG    . ASN B 2 163  ? 207.132 361.620 216.381 1.00 101.08 ? 163  ASN C CG    1 
ATOM   8920  O OD1   . ASN B 2 163  ? 207.268 360.403 216.260 1.00 101.08 ? 163  ASN C OD1   1 
ATOM   8921  N ND2   . ASN B 2 163  ? 206.814 362.410 215.362 1.00 101.08 ? 163  ASN C ND2   1 
ATOM   8922  N N     . ILE B 2 164  ? 204.058 361.367 217.548 1.00 95.86  ? 164  ILE C N     1 
ATOM   8923  C CA    . ILE B 2 164  ? 203.107 360.301 217.259 1.00 95.86  ? 164  ILE C CA    1 
ATOM   8924  C C     . ILE B 2 164  ? 203.526 359.592 215.978 1.00 95.86  ? 164  ILE C C     1 
ATOM   8925  O O     . ILE B 2 164  ? 204.106 360.205 215.073 1.00 95.86  ? 164  ILE C O     1 
ATOM   8926  C CB    . ILE B 2 164  ? 201.673 360.852 217.156 1.00 95.86  ? 164  ILE C CB    1 
ATOM   8927  C CG1   . ILE B 2 164  ? 201.365 361.342 215.739 1.00 95.86  ? 164  ILE C CG1   1 
ATOM   8928  C CG2   . ILE B 2 164  ? 201.461 361.968 218.167 1.00 95.86  ? 164  ILE C CG2   1 
ATOM   8929  C CD1   . ILE B 2 164  ? 199.886 361.430 215.431 1.00 95.86  ? 164  ILE C CD1   1 
ATOM   8930  N N     . LYS B 2 165  ? 203.270 358.287 215.919 1.00 92.53  ? 165  LYS C N     1 
ATOM   8931  C CA    . LYS B 2 165  ? 203.558 357.472 214.748 1.00 92.53  ? 165  LYS C CA    1 
ATOM   8932  C C     . LYS B 2 165  ? 202.399 356.515 214.509 1.00 92.53  ? 165  LYS C C     1 
ATOM   8933  O O     . LYS B 2 165  ? 201.909 355.880 215.449 1.00 92.53  ? 165  LYS C O     1 
ATOM   8934  C CB    . LYS B 2 165  ? 204.868 356.700 214.919 1.00 92.53  ? 165  LYS C CB    1 
ATOM   8935  C CG    . LYS B 2 165  ? 205.233 356.397 216.359 1.00 92.53  ? 165  LYS C CG    1 
ATOM   8936  C CD    . LYS B 2 165  ? 206.693 355.995 216.475 1.00 92.53  ? 165  LYS C CD    1 
ATOM   8937  C CE    . LYS B 2 165  ? 207.612 357.119 216.025 1.00 92.53  ? 165  LYS C CE    1 
ATOM   8938  N NZ    . LYS B 2 165  ? 209.041 356.700 216.019 1.00 92.53  ? 165  LYS C NZ    1 
ATOM   8939  N N     . LEU B 2 166  ? 201.967 356.417 213.256 1.00 89.22  ? 166  LEU C N     1 
ATOM   8940  C CA    . LEU B 2 166  ? 200.828 355.574 212.920 1.00 89.22  ? 166  LEU C CA    1 
ATOM   8941  C C     . LEU B 2 166  ? 201.242 354.109 212.832 1.00 89.22  ? 166  LEU C C     1 
ATOM   8942  O O     . LEU B 2 166  ? 202.337 353.781 212.366 1.00 89.22  ? 166  LEU C O     1 
ATOM   8943  C CB    . LEU B 2 166  ? 200.207 356.033 211.602 1.00 89.22  ? 166  LEU C CB    1 
ATOM   8944  C CG    . LEU B 2 166  ? 198.874 355.393 211.218 1.00 89.22  ? 166  LEU C CG    1 
ATOM   8945  C CD1   . LEU B 2 166  ? 197.739 356.049 211.977 1.00 89.22  ? 166  LEU C CD1   1 
ATOM   8946  C CD2   . LEU B 2 166  ? 198.656 355.521 209.723 1.00 89.22  ? 166  LEU C CD2   1 
ATOM   8947  N N     . THR B 2 167  ? 200.353 353.228 213.285 1.00 89.70  ? 167  THR C N     1 
ATOM   8948  C CA    . THR B 2 167  ? 200.604 351.793 213.305 1.00 89.70  ? 167  THR C CA    1 
ATOM   8949  C C     . THR B 2 167  ? 199.347 351.109 212.762 1.00 89.70  ? 167  THR C C     1 
ATOM   8950  O O     . THR B 2 167  ? 198.404 351.775 212.320 1.00 89.70  ? 167  THR C O     1 
ATOM   8951  C CB    . THR B 2 167  ? 200.990 351.355 214.728 1.00 89.70  ? 167  THR C CB    1 
ATOM   8952  O OG1   . THR B 2 167  ? 201.968 352.263 215.247 1.00 89.70  ? 167  THR C OG1   1 
ATOM   8953  C CG2   . THR B 2 167  ? 201.619 349.963 214.733 1.00 89.70  ? 167  THR C CG2   1 
ATOM   8954  N N     . ASP B 2 168  ? 199.333 349.774 212.785 1.00 96.84  ? 168  ASP C N     1 
ATOM   8955  C CA    . ASP B 2 168  ? 198.203 348.968 212.319 1.00 96.84  ? 168  ASP C CA    1 
ATOM   8956  C C     . ASP B 2 168  ? 197.902 349.242 210.843 1.00 96.84  ? 168  ASP C C     1 
ATOM   8957  O O     . ASP B 2 168  ? 196.834 349.732 210.473 1.00 96.84  ? 168  ASP C O     1 
ATOM   8958  C CB    . ASP B 2 168  ? 196.965 349.200 213.192 1.00 96.84  ? 168  ASP C CB    1 
ATOM   8959  C CG    . ASP B 2 168  ? 195.891 348.152 212.973 1.00 96.84  ? 168  ASP C CG    1 
ATOM   8960  O OD1   . ASP B 2 168  ? 196.205 347.088 212.399 1.00 96.84  ? 168  ASP C OD1   1 
ATOM   8961  O OD2   . ASP B 2 168  ? 194.733 348.392 213.374 1.00 96.84  ? 168  ASP C OD2   1 
ATOM   8962  N N     . PHE B 2 169  ? 198.877 348.907 209.999 1.00 98.06  ? 169  PHE C N     1 
ATOM   8963  C CA    . PHE B 2 169  ? 198.750 349.075 208.557 1.00 98.06  ? 169  PHE C CA    1 
ATOM   8964  C C     . PHE B 2 169  ? 198.041 347.908 207.881 1.00 98.06  ? 169  PHE C C     1 
ATOM   8965  O O     . PHE B 2 169  ? 197.872 347.936 206.657 1.00 98.06  ? 169  PHE C O     1 
ATOM   8966  C CB    . PHE B 2 169  ? 200.133 349.268 207.929 1.00 98.06  ? 169  PHE C CB    1 
ATOM   8967  C CG    . PHE B 2 169  ? 200.570 350.703 207.852 1.00 98.06  ? 169  PHE C CG    1 
ATOM   8968  C CD1   . PHE B 2 169  ? 199.644 351.714 207.660 1.00 98.06  ? 169  PHE C CD1   1 
ATOM   8969  C CD2   . PHE B 2 169  ? 201.907 351.042 207.975 1.00 98.06  ? 169  PHE C CD2   1 
ATOM   8970  C CE1   . PHE B 2 169  ? 200.043 353.035 207.588 1.00 98.06  ? 169  PHE C CE1   1 
ATOM   8971  C CE2   . PHE B 2 169  ? 202.313 352.361 207.905 1.00 98.06  ? 169  PHE C CE2   1 
ATOM   8972  C CZ    . PHE B 2 169  ? 201.379 353.359 207.712 1.00 98.06  ? 169  PHE C CZ    1 
ATOM   8973  N N     . GLY B 2 170  ? 197.634 346.887 208.639 1.00 103.55 ? 170  GLY C N     1 
ATOM   8974  C CA    . GLY B 2 170  ? 196.974 345.742 208.031 1.00 103.55 ? 170  GLY C CA    1 
ATOM   8975  C C     . GLY B 2 170  ? 195.651 346.097 207.380 1.00 103.55 ? 170  GLY C C     1 
ATOM   8976  O O     . GLY B 2 170  ? 195.333 345.608 206.293 1.00 103.55 ? 170  GLY C O     1 
ATOM   8977  N N     . PHE B 2 171  ? 194.859 346.948 208.037 1.00 100.39 ? 171  PHE C N     1 
ATOM   8978  C CA    . PHE B 2 171  ? 193.577 347.353 207.466 1.00 100.39 ? 171  PHE C CA    1 
ATOM   8979  C C     . PHE B 2 171  ? 193.771 348.180 206.202 1.00 100.39 ? 171  PHE C C     1 
ATOM   8980  O O     . PHE B 2 171  ? 192.972 348.087 205.262 1.00 100.39 ? 171  PHE C O     1 
ATOM   8981  C CB    . PHE B 2 171  ? 192.764 348.134 208.499 1.00 100.39 ? 171  PHE C CB    1 
ATOM   8982  C CG    . PHE B 2 171  ? 191.990 347.262 209.445 1.00 100.39 ? 171  PHE C CG    1 
ATOM   8983  C CD1   . PHE B 2 171  ? 190.826 346.637 209.033 1.00 100.39 ? 171  PHE C CD1   1 
ATOM   8984  C CD2   . PHE B 2 171  ? 192.424 347.070 210.747 1.00 100.39 ? 171  PHE C CD2   1 
ATOM   8985  C CE1   . PHE B 2 171  ? 190.108 345.834 209.898 1.00 100.39 ? 171  PHE C CE1   1 
ATOM   8986  C CE2   . PHE B 2 171  ? 191.710 346.267 211.618 1.00 100.39 ? 171  PHE C CE2   1 
ATOM   8987  C CZ    . PHE B 2 171  ? 190.551 345.649 211.192 1.00 100.39 ? 171  PHE C CZ    1 
ATOM   8988  N N     . SER B 2 172  ? 194.821 348.996 206.163 1.00 102.10 ? 172  SER C N     1 
ATOM   8989  C CA    . SER B 2 172  ? 195.093 349.806 204.984 1.00 102.10 ? 172  SER C CA    1 
ATOM   8990  C C     . SER B 2 172  ? 195.443 348.919 203.797 1.00 102.10 ? 172  SER C C     1 
ATOM   8991  O O     . SER B 2 172  ? 196.118 347.895 203.940 1.00 102.10 ? 172  SER C O     1 
ATOM   8992  C CB    . SER B 2 172  ? 196.237 350.780 205.267 1.00 102.10 ? 172  SER C CB    1 
ATOM   8993  O OG    . SER B 2 172  ? 197.484 350.221 204.893 1.00 102.10 ? 172  SER C OG    1 
ATOM   8994  N N     . CYS B 2 173  ? 194.972 349.314 202.616 1.00 105.60 ? 173  CYS C N     1 
ATOM   8995  C CA    . CYS B 2 173  ? 195.298 348.619 201.381 1.00 105.60 ? 173  CYS C CA    1 
ATOM   8996  C C     . CYS B 2 173  ? 195.560 349.646 200.291 1.00 105.60 ? 173  CYS C C     1 
ATOM   8997  O O     . CYS B 2 173  ? 194.964 350.726 200.277 1.00 105.60 ? 173  CYS C O     1 
ATOM   8998  C CB    . CYS B 2 173  ? 194.181 347.657 200.953 1.00 105.60 ? 173  CYS C CB    1 
ATOM   8999  S SG    . CYS B 2 173  ? 192.705 348.462 200.299 1.00 105.60 ? 173  CYS C SG    1 
ATOM   9000  N N     . GLN B 2 174  ? 196.464 349.300 199.378 1.00 109.23 ? 174  GLN C N     1 
ATOM   9001  C CA    . GLN B 2 174  ? 196.789 350.198 198.280 1.00 109.23 ? 174  GLN C CA    1 
ATOM   9002  C C     . GLN B 2 174  ? 195.632 350.247 197.289 1.00 109.23 ? 174  GLN C C     1 
ATOM   9003  O O     . GLN B 2 174  ? 194.955 349.244 197.047 1.00 109.23 ? 174  GLN C O     1 
ATOM   9004  C CB    . GLN B 2 174  ? 198.080 349.752 197.589 1.00 109.23 ? 174  GLN C CB    1 
ATOM   9005  C CG    . GLN B 2 174  ? 197.892 349.078 196.237 1.00 109.23 ? 174  GLN C CG    1 
ATOM   9006  C CD    . GLN B 2 174  ? 197.925 347.567 196.328 1.00 109.23 ? 174  GLN C CD    1 
ATOM   9007  O OE1   . GLN B 2 174  ? 197.929 346.998 197.418 1.00 109.23 ? 174  GLN C OE1   1 
ATOM   9008  N NE2   . GLN B 2 174  ? 197.944 346.906 195.175 1.00 109.23 ? 174  GLN C NE2   1 
ATOM   9009  N N     . LEU B 2 175  ? 195.377 351.435 196.746 1.00 113.82 ? 175  LEU C N     1 
ATOM   9010  C CA    . LEU B 2 175  ? 194.272 351.635 195.822 1.00 113.82 ? 175  LEU C CA    1 
ATOM   9011  C C     . LEU B 2 175  ? 194.738 352.407 194.596 1.00 113.82 ? 175  LEU C C     1 
ATOM   9012  O O     . LEU B 2 175  ? 195.690 353.190 194.653 1.00 113.82 ? 175  LEU C O     1 
ATOM   9013  C CB    . LEU B 2 175  ? 193.085 352.342 196.524 1.00 113.82 ? 175  LEU C CB    1 
ATOM   9014  C CG    . LEU B 2 175  ? 193.117 353.760 197.117 1.00 113.82 ? 175  LEU C CG    1 
ATOM   9015  C CD1   . LEU B 2 175  ? 193.316 354.880 196.095 1.00 113.82 ? 175  LEU C CD1   1 
ATOM   9016  C CD2   . LEU B 2 175  ? 191.849 353.999 197.928 1.00 113.82 ? 175  LEU C CD2   1 
ATOM   9017  N N     . GLU B 2 176  ? 194.052 352.167 193.483 1.00 123.52 ? 176  GLU C N     1 
ATOM   9018  C CA    . GLU B 2 176  ? 194.246 352.789 192.187 1.00 123.52 ? 176  GLU C CA    1 
ATOM   9019  C C     . GLU B 2 176  ? 193.174 353.847 191.950 1.00 123.52 ? 176  GLU C C     1 
ATOM   9020  O O     . GLU B 2 176  ? 192.083 353.766 192.521 1.00 123.52 ? 176  GLU C O     1 
ATOM   9021  C CB    . GLU B 2 176  ? 194.182 351.743 191.066 1.00 123.52 ? 176  GLU C CB    1 
ATOM   9022  C CG    . GLU B 2 176  ? 194.968 352.083 189.809 1.00 123.52 ? 176  GLU C CG    1 
ATOM   9023  C CD    . GLU B 2 176  ? 194.067 352.501 188.664 1.00 123.52 ? 176  GLU C CD    1 
ATOM   9024  O OE1   . GLU B 2 176  ? 193.158 351.721 188.309 1.00 123.52 ? 176  GLU C OE1   1 
ATOM   9025  O OE2   . GLU B 2 176  ? 194.265 353.609 188.122 1.00 123.52 ? 176  GLU C OE2   1 
ATOM   9026  N N     . PRO B 2 177  ? 193.460 354.874 191.153 1.00 126.92 ? 177  PRO C N     1 
ATOM   9027  C CA    . PRO B 2 177  ? 192.392 355.791 190.742 1.00 126.92 ? 177  PRO C CA    1 
ATOM   9028  C C     . PRO B 2 177  ? 191.287 355.054 189.994 1.00 126.92 ? 177  PRO C C     1 
ATOM   9029  O O     . PRO B 2 177  ? 191.544 354.148 189.199 1.00 126.92 ? 177  PRO C O     1 
ATOM   9030  C CB    . PRO B 2 177  ? 193.118 356.798 189.842 1.00 126.92 ? 177  PRO C CB    1 
ATOM   9031  C CG    . PRO B 2 177  ? 194.523 356.781 190.333 1.00 126.92 ? 177  PRO C CG    1 
ATOM   9032  C CD    . PRO B 2 177  ? 194.795 355.375 190.780 1.00 126.92 ? 177  PRO C CD    1 
ATOM   9033  N N     . GLY B 2 178  ? 190.045 355.450 190.266 1.00 127.83 ? 178  GLY C N     1 
ATOM   9034  C CA    . GLY B 2 178  ? 188.896 354.904 189.573 1.00 127.83 ? 178  GLY C CA    1 
ATOM   9035  C C     . GLY B 2 178  ? 188.242 353.692 190.205 1.00 127.83 ? 178  GLY C C     1 
ATOM   9036  O O     . GLY B 2 178  ? 187.221 353.226 189.684 1.00 127.83 ? 178  GLY C O     1 
ATOM   9037  N N     . GLU B 2 179  ? 188.778 353.164 191.302 1.00 128.25 ? 179  GLU C N     1 
ATOM   9038  C CA    . GLU B 2 179  ? 188.151 352.061 192.017 1.00 128.25 ? 179  GLU C CA    1 
ATOM   9039  C C     . GLU B 2 179  ? 187.726 352.516 193.407 1.00 128.25 ? 179  GLU C C     1 
ATOM   9040  O O     . GLU B 2 179  ? 188.401 353.336 194.038 1.00 128.25 ? 179  GLU C O     1 
ATOM   9041  C CB    . GLU B 2 179  ? 189.081 350.849 192.131 1.00 128.25 ? 179  GLU C CB    1 
ATOM   9042  C CG    . GLU B 2 179  ? 190.490 351.143 192.607 1.00 128.25 ? 179  GLU C CG    1 
ATOM   9043  C CD    . GLU B 2 179  ? 191.372 349.911 192.563 1.00 128.25 ? 179  GLU C CD    1 
ATOM   9044  O OE1   . GLU B 2 179  ? 192.384 349.871 193.295 1.00 128.25 ? 179  GLU C OE1   1 
ATOM   9045  O OE2   . GLU B 2 179  ? 191.039 348.975 191.806 1.00 128.25 ? 179  GLU C OE2   1 
ATOM   9046  N N     . ARG B 2 180  ? 186.604 351.976 193.877 1.00 125.98 ? 180  ARG C N     1 
ATOM   9047  C CA    . ARG B 2 180  ? 186.030 352.333 195.166 1.00 125.98 ? 180  ARG C CA    1 
ATOM   9048  C C     . ARG B 2 180  ? 185.829 351.074 195.998 1.00 125.98 ? 180  ARG C C     1 
ATOM   9049  O O     . ARG B 2 180  ? 185.344 350.059 195.487 1.00 125.98 ? 180  ARG C O     1 
ATOM   9050  C CB    . ARG B 2 180  ? 184.698 353.067 194.988 1.00 125.98 ? 180  ARG C CB    1 
ATOM   9051  C CG    . ARG B 2 180  ? 184.620 353.966 193.760 1.00 125.98 ? 180  ARG C CG    1 
ATOM   9052  C CD    . ARG B 2 180  ? 185.533 355.176 193.883 1.00 125.98 ? 180  ARG C CD    1 
ATOM   9053  N NE    . ARG B 2 180  ? 185.258 355.946 195.090 1.00 125.98 ? 180  ARG C NE    1 
ATOM   9054  C CZ    . ARG B 2 180  ? 184.504 357.036 195.126 1.00 125.98 ? 180  ARG C CZ    1 
ATOM   9055  N NH1   . ARG B 2 180  ? 183.921 357.509 194.037 1.00 125.98 ? 180  ARG C NH1   1 
ATOM   9056  N NH2   . ARG B 2 180  ? 184.327 357.664 196.285 1.00 125.98 ? 180  ARG C NH2   1 
ATOM   9057  N N     . LEU B 2 181  ? 186.197 351.145 197.274 1.00 120.22 ? 181  LEU C N     1 
ATOM   9058  C CA    . LEU B 2 181  ? 186.070 350.013 198.179 1.00 120.22 ? 181  LEU C CA    1 
ATOM   9059  C C     . LEU B 2 181  ? 184.646 349.909 198.719 1.00 120.22 ? 181  LEU C C     1 
ATOM   9060  O O     . LEU B 2 181  ? 183.898 350.887 198.771 1.00 120.22 ? 181  LEU C O     1 
ATOM   9061  C CB    . LEU B 2 181  ? 187.056 350.137 199.342 1.00 120.22 ? 181  LEU C CB    1 
ATOM   9062  C CG    . LEU B 2 181  ? 188.532 350.361 199.006 1.00 120.22 ? 181  LEU C CG    1 
ATOM   9063  C CD1   . LEU B 2 181  ? 188.876 351.843 198.974 1.00 120.22 ? 181  LEU C CD1   1 
ATOM   9064  C CD2   . LEU B 2 181  ? 189.402 349.634 200.011 1.00 120.22 ? 181  LEU C CD2   1 
ATOM   9065  N N     . ARG B 2 182  ? 184.279 348.697 199.137 1.00 122.22 ? 182  ARG C N     1 
ATOM   9066  C CA    . ARG B 2 182  ? 182.939 348.437 199.650 1.00 122.22 ? 182  ARG C CA    1 
ATOM   9067  C C     . ARG B 2 182  ? 182.901 347.804 201.033 1.00 122.22 ? 182  ARG C C     1 
ATOM   9068  O O     . ARG B 2 182  ? 181.851 347.872 201.684 1.00 122.22 ? 182  ARG C O     1 
ATOM   9069  C CB    . ARG B 2 182  ? 182.157 347.538 198.680 1.00 122.22 ? 182  ARG C CB    1 
ATOM   9070  C CG    . ARG B 2 182  ? 181.485 348.293 197.544 1.00 122.22 ? 182  ARG C CG    1 
ATOM   9071  C CD    . ARG B 2 182  ? 180.254 347.557 197.043 1.00 122.22 ? 182  ARG C CD    1 
ATOM   9072  N NE    . ARG B 2 182  ? 179.164 348.472 196.729 1.00 122.22 ? 182  ARG C NE    1 
ATOM   9073  C CZ    . ARG B 2 182  ? 178.228 348.847 197.590 1.00 122.22 ? 182  ARG C CZ    1 
ATOM   9074  N NH1   . ARG B 2 182  ? 178.217 348.400 198.836 1.00 122.22 ? 182  ARG C NH1   1 
ATOM   9075  N NH2   . ARG B 2 182  ? 177.280 349.690 197.193 1.00 122.22 ? 182  ARG C NH2   1 
ATOM   9076  N N     . GLU B 2 183  ? 183.986 347.193 201.504 1.00 119.62 ? 183  GLU C N     1 
ATOM   9077  C CA    . GLU B 2 183  ? 183.977 346.573 202.822 1.00 119.62 ? 183  GLU C CA    1 
ATOM   9078  C C     . GLU B 2 183  ? 183.904 347.634 203.914 1.00 119.62 ? 183  GLU C C     1 
ATOM   9079  O O     . GLU B 2 183  ? 184.449 348.733 203.776 1.00 119.62 ? 183  GLU C O     1 
ATOM   9080  C CB    . GLU B 2 183  ? 185.217 345.696 203.010 1.00 119.62 ? 183  GLU C CB    1 
ATOM   9081  C CG    . GLU B 2 183  ? 186.525 346.458 203.184 1.00 119.62 ? 183  GLU C CG    1 
ATOM   9082  C CD    . GLU B 2 183  ? 187.176 346.828 201.863 1.00 119.62 ? 183  GLU C CD    1 
ATOM   9083  O OE1   . GLU B 2 183  ? 186.468 346.867 200.834 1.00 119.62 ? 183  GLU C OE1   1 
ATOM   9084  O OE2   . GLU B 2 183  ? 188.399 347.079 201.854 1.00 119.62 ? 183  GLU C OE2   1 
ATOM   9085  N N     . VAL B 2 184  ? 183.214 347.303 205.002 1.00 117.15 ? 184  VAL C N     1 
ATOM   9086  C CA    . VAL B 2 184  ? 183.012 348.210 206.126 1.00 117.15 ? 184  VAL C CA    1 
ATOM   9087  C C     . VAL B 2 184  ? 183.684 347.617 207.357 1.00 117.15 ? 184  VAL C C     1 
ATOM   9088  O O     . VAL B 2 184  ? 183.483 346.439 207.679 1.00 117.15 ? 184  VAL C O     1 
ATOM   9089  C CB    . VAL B 2 184  ? 181.516 348.478 206.374 1.00 117.15 ? 184  VAL C CB    1 
ATOM   9090  C CG1   . VAL B 2 184  ? 180.735 347.172 206.465 1.00 117.15 ? 184  VAL C CG1   1 
ATOM   9091  C CG2   . VAL B 2 184  ? 181.325 349.310 207.634 1.00 117.15 ? 184  VAL C CG2   1 
ATOM   9092  N N     . CYS B 2 185  ? 184.496 348.427 208.032 1.00 116.11 ? 185  CYS C N     1 
ATOM   9093  C CA    . CYS B 2 185  ? 185.196 347.987 209.230 1.00 116.11 ? 185  CYS C CA    1 
ATOM   9094  C C     . CYS B 2 185  ? 185.574 349.208 210.056 1.00 116.11 ? 185  CYS C C     1 
ATOM   9095  O O     . CYS B 2 185  ? 185.578 350.338 209.561 1.00 116.11 ? 185  CYS C O     1 
ATOM   9096  C CB    . CYS B 2 185  ? 186.440 347.163 208.884 1.00 116.11 ? 185  CYS C CB    1 
ATOM   9097  S SG    . CYS B 2 185  ? 187.762 348.111 208.094 1.00 116.11 ? 185  CYS C SG    1 
ATOM   9098  N N     . GLY B 2 186  ? 185.892 348.962 211.320 1.00 113.62 ? 186  GLY C N     1 
ATOM   9099  C CA    . GLY B 2 186  ? 186.330 350.001 212.231 1.00 113.62 ? 186  GLY C CA    1 
ATOM   9100  C C     . GLY B 2 186  ? 185.317 350.254 213.335 1.00 113.62 ? 186  GLY C C     1 
ATOM   9101  O O     . GLY B 2 186  ? 184.256 349.632 213.410 1.00 113.62 ? 186  GLY C O     1 
ATOM   9102  N N     . THR B 2 187  ? 185.682 351.192 214.203 1.00 101.89 ? 187  THR C N     1 
ATOM   9103  C CA    . THR B 2 187  ? 184.808 351.575 215.301 1.00 101.89 ? 187  THR C CA    1 
ATOM   9104  C C     . THR B 2 187  ? 183.540 352.223 214.745 1.00 101.89 ? 187  THR C C     1 
ATOM   9105  O O     . THR B 2 187  ? 183.616 353.032 213.813 1.00 101.89 ? 187  THR C O     1 
ATOM   9106  C CB    . THR B 2 187  ? 185.540 352.533 216.247 1.00 101.89 ? 187  THR C CB    1 
ATOM   9107  O OG1   . THR B 2 187  ? 186.365 351.779 217.144 1.00 101.89 ? 187  THR C OG1   1 
ATOM   9108  C CG2   . THR B 2 187  ? 184.561 353.362 217.063 1.00 101.89 ? 187  THR C CG2   1 
ATOM   9109  N N     . PRO B 2 188  ? 182.363 351.890 215.285 1.00 104.41 ? 188  PRO C N     1 
ATOM   9110  C CA    . PRO B 2 188  ? 181.108 352.370 214.678 1.00 104.41 ? 188  PRO C CA    1 
ATOM   9111  C C     . PRO B 2 188  ? 180.962 353.884 214.638 1.00 104.41 ? 188  PRO C C     1 
ATOM   9112  O O     . PRO B 2 188  ? 180.140 354.385 213.860 1.00 104.41 ? 188  PRO C O     1 
ATOM   9113  C CB    . PRO B 2 188  ? 180.025 351.731 215.559 1.00 104.41 ? 188  PRO C CB    1 
ATOM   9114  C CG    . PRO B 2 188  ? 180.683 350.538 216.165 1.00 104.41 ? 188  PRO C CG    1 
ATOM   9115  C CD    . PRO B 2 188  ? 182.120 350.917 216.365 1.00 104.41 ? 188  PRO C CD    1 
ATOM   9116  N N     . SER B 2 189  ? 181.714 354.630 215.444 1.00 95.14  ? 189  SER C N     1 
ATOM   9117  C CA    . SER B 2 189  ? 181.616 356.084 215.460 1.00 95.14  ? 189  SER C CA    1 
ATOM   9118  C C     . SER B 2 189  ? 182.621 356.759 214.531 1.00 95.14  ? 189  SER C C     1 
ATOM   9119  O O     . SER B 2 189  ? 182.826 357.972 214.640 1.00 95.14  ? 189  SER C O     1 
ATOM   9120  C CB    . SER B 2 189  ? 181.792 356.611 216.887 1.00 95.14  ? 189  SER C CB    1 
ATOM   9121  O OG    . SER B 2 189  ? 182.974 356.106 217.481 1.00 95.14  ? 189  SER C OG    1 
ATOM   9122  N N     . TYR B 2 190  ? 183.249 356.009 213.629 1.00 94.50  ? 190  TYR C N     1 
ATOM   9123  C CA    . TYR B 2 190  ? 184.261 356.531 212.712 1.00 94.50  ? 190  TYR C CA    1 
ATOM   9124  C C     . TYR B 2 190  ? 183.908 356.188 211.269 1.00 94.50  ? 190  TYR C C     1 
ATOM   9125  O O     . TYR B 2 190  ? 184.744 355.717 210.494 1.00 94.50  ? 190  TYR C O     1 
ATOM   9126  C CB    . TYR B 2 190  ? 185.648 355.993 213.056 1.00 94.50  ? 190  TYR C CB    1 
ATOM   9127  C CG    . TYR B 2 190  ? 186.268 356.581 214.306 1.00 94.50  ? 190  TYR C CG    1 
ATOM   9128  C CD1   . TYR B 2 190  ? 185.768 356.277 215.565 1.00 94.50  ? 190  TYR C CD1   1 
ATOM   9129  C CD2   . TYR B 2 190  ? 187.365 357.428 214.225 1.00 94.50  ? 190  TYR C CD2   1 
ATOM   9130  C CE1   . TYR B 2 190  ? 186.335 356.809 216.708 1.00 94.50  ? 190  TYR C CE1   1 
ATOM   9131  C CE2   . TYR B 2 190  ? 187.941 357.963 215.362 1.00 94.50  ? 190  TYR C CE2   1 
ATOM   9132  C CZ    . TYR B 2 190  ? 187.421 357.651 216.600 1.00 94.50  ? 190  TYR C CZ    1 
ATOM   9133  O OH    . TYR B 2 190  ? 187.990 358.182 217.735 1.00 94.50  ? 190  TYR C OH    1 
ATOM   9134  N N     . LEU B 2 191  ? 182.655 356.420 210.884 1.00 103.29 ? 191  LEU C N     1 
ATOM   9135  C CA    . LEU B 2 191  ? 182.186 356.134 209.533 1.00 103.29 ? 191  LEU C CA    1 
ATOM   9136  C C     . LEU B 2 191  ? 181.694 357.410 208.866 1.00 103.29 ? 191  LEU C C     1 
ATOM   9137  O O     . LEU B 2 191  ? 180.929 358.175 209.461 1.00 103.29 ? 191  LEU C O     1 
ATOM   9138  C CB    . LEU B 2 191  ? 181.071 355.081 209.533 1.00 103.29 ? 191  LEU C CB    1 
ATOM   9139  C CG    . LEU B 2 191  ? 181.458 353.618 209.772 1.00 103.29 ? 191  LEU C CG    1 
ATOM   9140  C CD1   . LEU B 2 191  ? 182.632 353.218 208.888 1.00 103.29 ? 191  LEU C CD1   1 
ATOM   9141  C CD2   . LEU B 2 191  ? 181.760 353.339 211.232 1.00 103.29 ? 191  LEU C CD2   1 
ATOM   9142  N N     . ALA B 2 192  ? 182.137 357.628 207.632 1.00 108.51 ? 192  ALA C N     1 
ATOM   9143  C CA    . ALA B 2 192  ? 181.664 358.719 206.797 1.00 108.51 ? 192  ALA C CA    1 
ATOM   9144  C C     . ALA B 2 192  ? 180.267 358.406 206.265 1.00 108.51 ? 192  ALA C C     1 
ATOM   9145  O O     . ALA B 2 192  ? 179.843 357.247 206.263 1.00 108.51 ? 192  ALA C O     1 
ATOM   9146  C CB    . ALA B 2 192  ? 182.641 358.947 205.646 1.00 108.51 ? 192  ALA C CB    1 
ATOM   9147  N N     . PRO B 2 193  ? 179.519 359.422 205.815 1.00 110.68 ? 193  PRO C N     1 
ATOM   9148  C CA    . PRO B 2 193  ? 178.202 359.129 205.225 1.00 110.68 ? 193  PRO C CA    1 
ATOM   9149  C C     . PRO B 2 193  ? 178.299 358.286 203.970 1.00 110.68 ? 193  PRO C C     1 
ATOM   9150  O O     . PRO B 2 193  ? 177.313 357.648 203.577 1.00 110.68 ? 193  PRO C O     1 
ATOM   9151  C CB    . PRO B 2 193  ? 177.627 360.522 204.935 1.00 110.68 ? 193  PRO C CB    1 
ATOM   9152  C CG    . PRO B 2 193  ? 178.813 361.394 204.784 1.00 110.68 ? 193  PRO C CG    1 
ATOM   9153  C CD    . PRO B 2 193  ? 179.847 360.856 205.726 1.00 110.68 ? 193  PRO C CD    1 
ATOM   9154  N N     . GLU B 2 194  ? 179.468 358.267 203.327 1.00 110.89 ? 194  GLU C N     1 
ATOM   9155  C CA    . GLU B 2 194  ? 179.667 357.396 202.175 1.00 110.89 ? 194  GLU C CA    1 
ATOM   9156  C C     . GLU B 2 194  ? 179.506 355.932 202.561 1.00 110.89 ? 194  GLU C C     1 
ATOM   9157  O O     . GLU B 2 194  ? 178.945 355.143 201.796 1.00 110.89 ? 194  GLU C O     1 
ATOM   9158  C CB    . GLU B 2 194  ? 181.044 357.644 201.561 1.00 110.89 ? 194  GLU C CB    1 
ATOM   9159  N N     . ILE B 2 195  ? 179.986 355.550 203.747 1.00 110.16 ? 195  ILE C N     1 
ATOM   9160  C CA    . ILE B 2 195  ? 179.905 354.152 204.168 1.00 110.16 ? 195  ILE C CA    1 
ATOM   9161  C C     . ILE B 2 195  ? 178.450 353.712 204.286 1.00 110.16 ? 195  ILE C C     1 
ATOM   9162  O O     . ILE B 2 195  ? 178.046 352.682 203.731 1.00 110.16 ? 195  ILE C O     1 
ATOM   9163  C CB    . ILE B 2 195  ? 180.665 353.941 205.491 1.00 110.16 ? 195  ILE C CB    1 
ATOM   9164  C CG1   . ILE B 2 195  ? 182.175 353.920 205.251 1.00 110.16 ? 195  ILE C CG1   1 
ATOM   9165  C CG2   . ILE B 2 195  ? 180.217 352.652 206.165 1.00 110.16 ? 195  ILE C CG2   1 
ATOM   9166  C CD1   . ILE B 2 195  ? 182.826 355.282 205.286 1.00 110.16 ? 195  ILE C CD1   1 
ATOM   9167  N N     . ILE B 2 196  ? 177.639 354.491 205.004 1.00 112.35 ? 196  ILE C N     1 
ATOM   9168  C CA    . ILE B 2 196  ? 176.241 354.117 205.197 1.00 112.35 ? 196  ILE C CA    1 
ATOM   9169  C C     . ILE B 2 196  ? 175.470 354.228 203.887 1.00 112.35 ? 196  ILE C C     1 
ATOM   9170  O O     . ILE B 2 196  ? 174.537 353.456 203.635 1.00 112.35 ? 196  ILE C O     1 
ATOM   9171  C CB    . ILE B 2 196  ? 175.601 354.959 206.318 1.00 112.35 ? 196  ILE C CB    1 
ATOM   9172  C CG1   . ILE B 2 196  ? 175.820 356.455 206.081 1.00 112.35 ? 196  ILE C CG1   1 
ATOM   9173  C CG2   . ILE B 2 196  ? 176.155 354.547 207.674 1.00 112.35 ? 196  ILE C CG2   1 
ATOM   9174  C CD1   . ILE B 2 196  ? 174.631 357.162 205.461 1.00 112.35 ? 196  ILE C CD1   1 
ATOM   9175  N N     . GLU B 2 197  ? 175.838 355.190 203.035 1.00 116.04 ? 197  GLU C N     1 
ATOM   9176  C CA    . GLU B 2 197  ? 175.185 355.307 201.736 1.00 116.04 ? 197  GLU C CA    1 
ATOM   9177  C C     . GLU B 2 197  ? 175.458 354.084 200.867 1.00 116.04 ? 197  GLU C C     1 
ATOM   9178  O O     . GLU B 2 197  ? 174.543 353.551 200.229 1.00 116.04 ? 197  GLU C O     1 
ATOM   9179  C CB    . GLU B 2 197  ? 175.645 356.582 201.030 1.00 116.04 ? 197  GLU C CB    1 
ATOM   9180  N N     . CYS B 2 198  ? 176.710 353.623 200.834 1.00 122.63 ? 198  CYS C N     1 
ATOM   9181  C CA    . CYS B 2 198  ? 177.054 352.455 200.028 1.00 122.63 ? 198  CYS C CA    1 
ATOM   9182  C C     . CYS B 2 198  ? 176.448 351.186 200.607 1.00 122.63 ? 198  CYS C C     1 
ATOM   9183  O O     . CYS B 2 198  ? 176.027 350.293 199.862 1.00 122.63 ? 198  CYS C O     1 
ATOM   9184  C CB    . CYS B 2 198  ? 178.571 352.316 199.923 1.00 122.63 ? 198  CYS C CB    1 
ATOM   9185  S SG    . CYS B 2 198  ? 179.400 353.730 199.179 1.00 122.63 ? 198  CYS C SG    1 
ATOM   9186  N N     . SER B 2 199  ? 176.396 351.086 201.931 1.00 116.66 ? 199  SER C N     1 
ATOM   9187  C CA    . SER B 2 199  ? 175.920 349.879 202.589 1.00 116.66 ? 199  SER C CA    1 
ATOM   9188  C C     . SER B 2 199  ? 174.410 349.860 202.784 1.00 116.66 ? 199  SER C C     1 
ATOM   9189  O O     . SER B 2 199  ? 173.902 348.932 203.423 1.00 116.66 ? 199  SER C O     1 
ATOM   9190  C CB    . SER B 2 199  ? 176.615 349.709 203.944 1.00 116.66 ? 199  SER C CB    1 
ATOM   9191  O OG    . SER B 2 199  ? 176.460 350.865 204.748 1.00 116.66 ? 199  SER C OG    1 
ATOM   9192  N N     . MET B 2 200  ? 173.683 350.857 202.274 1.00 121.75 ? 200  MET C N     1 
ATOM   9193  C CA    . MET B 2 200  ? 172.236 350.863 202.453 1.00 121.75 ? 200  MET C CA    1 
ATOM   9194  C C     . MET B 2 200  ? 171.612 349.652 201.771 1.00 121.75 ? 200  MET C C     1 
ATOM   9195  O O     . MET B 2 200  ? 171.152 348.730 202.453 1.00 121.75 ? 200  MET C O     1 
ATOM   9196  C CB    . MET B 2 200  ? 171.632 352.158 201.905 1.00 121.75 ? 200  MET C CB    1 
ATOM   9197  N N     . ASN B 2 201  ? 171.584 349.629 200.435 1.00 129.62 ? 201  ASN C N     1 
ATOM   9198  C CA    . ASN B 2 201  ? 171.450 348.369 199.707 1.00 129.62 ? 201  ASN C CA    1 
ATOM   9199  C C     . ASN B 2 201  ? 172.574 348.185 198.694 1.00 129.62 ? 201  ASN C C     1 
ATOM   9200  O O     . ASN B 2 201  ? 173.404 347.289 198.864 1.00 129.62 ? 201  ASN C O     1 
ATOM   9201  C CB    . ASN B 2 201  ? 170.076 348.301 199.038 1.00 129.62 ? 201  ASN C CB    1 
ATOM   9202  C CG    . ASN B 2 201  ? 169.613 349.650 198.521 1.00 129.62 ? 201  ASN C CG    1 
ATOM   9203  O OD1   . ASN B 2 201  ? 170.424 350.532 198.240 1.00 129.62 ? 201  ASN C OD1   1 
ATOM   9204  N ND2   . ASN B 2 201  ? 168.302 349.817 198.397 1.00 129.62 ? 201  ASN C ND2   1 
ATOM   9205  N N     . GLU B 2 202  ? 172.628 349.009 197.640 1.00 134.54 ? 202  GLU C N     1 
ATOM   9206  C CA    . GLU B 2 202  ? 173.725 348.955 196.681 1.00 134.54 ? 202  GLU C CA    1 
ATOM   9207  C C     . GLU B 2 202  ? 174.052 350.293 196.030 1.00 134.54 ? 202  GLU C C     1 
ATOM   9208  O O     . GLU B 2 202  ? 174.947 350.331 195.181 1.00 134.54 ? 202  GLU C O     1 
ATOM   9209  C CB    . GLU B 2 202  ? 173.409 347.905 195.596 1.00 134.54 ? 202  GLU C CB    1 
ATOM   9210  C CG    . GLU B 2 202  ? 172.618 348.432 194.403 1.00 134.54 ? 202  GLU C CG    1 
ATOM   9211  C CD    . GLU B 2 202  ? 171.217 348.878 194.777 1.00 134.54 ? 202  GLU C CD    1 
ATOM   9212  O OE1   . GLU B 2 202  ? 170.675 348.371 195.781 1.00 134.54 ? 202  GLU C OE1   1 
ATOM   9213  O OE2   . GLU B 2 202  ? 170.656 349.737 194.064 1.00 134.54 ? 202  GLU C OE2   1 
ATOM   9214  N N     . ASP B 2 203  ? 173.386 351.389 196.401 1.00 130.91 ? 203  ASP C N     1 
ATOM   9215  C CA    . ASP B 2 203  ? 173.318 352.559 195.527 1.00 130.91 ? 203  ASP C CA    1 
ATOM   9216  C C     . ASP B 2 203  ? 174.667 353.259 195.395 1.00 130.91 ? 203  ASP C C     1 
ATOM   9217  O O     . ASP B 2 203  ? 175.226 353.349 194.295 1.00 130.91 ? 203  ASP C O     1 
ATOM   9218  C CB    . ASP B 2 203  ? 172.252 353.531 196.039 1.00 130.91 ? 203  ASP C CB    1 
ATOM   9219  C CG    . ASP B 2 203  ? 172.179 353.574 197.551 1.00 130.91 ? 203  ASP C CG    1 
ATOM   9220  O OD1   . ASP B 2 203  ? 172.910 352.799 198.201 1.00 130.91 ? 203  ASP C OD1   1 
ATOM   9221  O OD2   . ASP B 2 203  ? 171.394 354.383 198.088 1.00 130.91 ? 203  ASP C OD2   1 
ATOM   9222  N N     . HIS B 2 204  ? 175.201 353.772 196.498 1.00 127.32 ? 204  HIS C N     1 
ATOM   9223  C CA    . HIS B 2 204  ? 176.391 354.607 196.417 1.00 127.32 ? 204  HIS C CA    1 
ATOM   9224  C C     . HIS B 2 204  ? 177.589 353.778 195.953 1.00 127.32 ? 204  HIS C C     1 
ATOM   9225  O O     . HIS B 2 204  ? 177.694 352.593 196.294 1.00 127.32 ? 204  HIS C O     1 
ATOM   9226  C CB    . HIS B 2 204  ? 176.680 355.259 197.769 1.00 127.32 ? 204  HIS C CB    1 
ATOM   9227  N N     . PRO B 2 205  ? 178.505 354.366 195.164 1.00 129.18 ? 205  PRO C N     1 
ATOM   9228  C CA    . PRO B 2 205  ? 179.574 353.573 194.535 1.00 129.18 ? 205  PRO C CA    1 
ATOM   9229  C C     . PRO B 2 205  ? 180.484 352.842 195.511 1.00 129.18 ? 205  PRO C C     1 
ATOM   9230  O O     . PRO B 2 205  ? 180.594 351.613 195.452 1.00 129.18 ? 205  PRO C O     1 
ATOM   9231  C CB    . PRO B 2 205  ? 180.361 354.622 193.735 1.00 129.18 ? 205  PRO C CB    1 
ATOM   9232  C CG    . PRO B 2 205  ? 179.406 355.752 193.534 1.00 129.18 ? 205  PRO C CG    1 
ATOM   9233  C CD    . PRO B 2 205  ? 178.555 355.782 194.764 1.00 129.18 ? 205  PRO C CD    1 
ATOM   9234  N N     . GLY B 2 206  ? 181.136 353.572 196.410 1.00 124.36 ? 206  GLY C N     1 
ATOM   9235  C CA    . GLY B 2 206  ? 182.083 352.940 197.310 1.00 124.36 ? 206  GLY C CA    1 
ATOM   9236  C C     . GLY B 2 206  ? 182.846 353.969 198.122 1.00 124.36 ? 206  GLY C C     1 
ATOM   9237  O O     . GLY B 2 206  ? 182.423 355.120 198.250 1.00 124.36 ? 206  GLY C O     1 
ATOM   9238  N N     . TYR B 2 207  ? 183.977 353.527 198.667 1.00 123.36 ? 207  TYR C N     1 
ATOM   9239  C CA    . TYR B 2 207  ? 184.808 354.368 199.513 1.00 123.36 ? 207  TYR C CA    1 
ATOM   9240  C C     . TYR B 2 207  ? 185.495 355.454 198.687 1.00 123.36 ? 207  TYR C C     1 
ATOM   9241  O O     . TYR B 2 207  ? 185.578 355.388 197.457 1.00 123.36 ? 207  TYR C O     1 
ATOM   9242  C CB    . TYR B 2 207  ? 185.856 353.527 200.241 1.00 123.36 ? 207  TYR C CB    1 
ATOM   9243  C CG    . TYR B 2 207  ? 185.384 352.924 201.545 1.00 123.36 ? 207  TYR C CG    1 
ATOM   9244  C CD1   . TYR B 2 207  ? 184.192 352.217 201.618 1.00 123.36 ? 207  TYR C CD1   1 
ATOM   9245  C CD2   . TYR B 2 207  ? 186.140 353.054 202.703 1.00 123.36 ? 207  TYR C CD2   1 
ATOM   9246  C CE1   . TYR B 2 207  ? 183.761 351.663 202.808 1.00 123.36 ? 207  TYR C CE1   1 
ATOM   9247  C CE2   . TYR B 2 207  ? 185.719 352.502 203.898 1.00 123.36 ? 207  TYR C CE2   1 
ATOM   9248  C CZ    . TYR B 2 207  ? 184.529 351.808 203.944 1.00 123.36 ? 207  TYR C CZ    1 
ATOM   9249  O OH    . TYR B 2 207  ? 184.105 351.257 205.131 1.00 123.36 ? 207  TYR C OH    1 
ATOM   9250  N N     . GLY B 2 208  ? 186.001 356.466 199.388 1.00 116.11 ? 208  GLY C N     1 
ATOM   9251  C CA    . GLY B 2 208  ? 186.706 357.557 198.745 1.00 116.11 ? 208  GLY C CA    1 
ATOM   9252  C C     . GLY B 2 208  ? 188.000 357.922 199.444 1.00 116.11 ? 208  GLY C C     1 
ATOM   9253  O O     . GLY B 2 208  ? 188.792 357.044 199.798 1.00 116.11 ? 208  GLY C O     1 
ATOM   9254  N N     . LYS B 2 209  ? 188.225 359.221 199.650 1.00 110.79 ? 209  LYS C N     1 
ATOM   9255  C CA    . LYS B 2 209  ? 189.437 359.701 200.298 1.00 110.79 ? 209  LYS C CA    1 
ATOM   9256  C C     . LYS B 2 209  ? 189.184 360.597 201.501 1.00 110.79 ? 209  LYS C C     1 
ATOM   9257  O O     . LYS B 2 209  ? 190.138 360.901 202.226 1.00 110.79 ? 209  LYS C O     1 
ATOM   9258  C CB    . LYS B 2 209  ? 190.318 360.461 199.293 1.00 110.79 ? 209  LYS C CB    1 
ATOM   9259  C CG    . LYS B 2 209  ? 191.498 359.658 198.766 1.00 110.79 ? 209  LYS C CG    1 
ATOM   9260  C CD    . LYS B 2 209  ? 192.275 360.443 197.721 1.00 110.79 ? 209  LYS C CD    1 
ATOM   9261  C CE    . LYS B 2 209  ? 193.653 359.843 197.487 1.00 110.79 ? 209  LYS C CE    1 
ATOM   9262  N NZ    . LYS B 2 209  ? 193.583 358.386 197.188 1.00 110.79 ? 209  LYS C NZ    1 
ATOM   9263  N N     . GLU B 2 210  ? 187.945 361.028 201.739 1.00 110.29 ? 210  GLU C N     1 
ATOM   9264  C CA    . GLU B 2 210  ? 187.640 361.922 202.848 1.00 110.29 ? 210  GLU C CA    1 
ATOM   9265  C C     . GLU B 2 210  ? 187.311 361.182 204.138 1.00 110.29 ? 210  GLU C C     1 
ATOM   9266  O O     . GLU B 2 210  ? 187.023 361.831 205.154 1.00 110.29 ? 210  GLU C O     1 
ATOM   9267  C CB    . GLU B 2 210  ? 186.479 362.844 202.468 1.00 110.29 ? 210  GLU C CB    1 
ATOM   9268  C CG    . GLU B 2 210  ? 186.888 364.075 201.669 1.00 110.29 ? 210  GLU C CG    1 
ATOM   9269  C CD    . GLU B 2 210  ? 187.330 363.747 200.253 1.00 110.29 ? 210  GLU C CD    1 
ATOM   9270  O OE1   . GLU B 2 210  ? 187.122 362.600 199.806 1.00 110.29 ? 210  GLU C OE1   1 
ATOM   9271  O OE2   . GLU B 2 210  ? 187.890 364.642 199.585 1.00 110.29 ? 210  GLU C OE2   1 
ATOM   9272  N N     . VAL B 2 211  ? 187.339 359.847 204.122 1.00 105.17 ? 211  VAL C N     1 
ATOM   9273  C CA    . VAL B 2 211  ? 187.162 359.086 205.355 1.00 105.17 ? 211  VAL C CA    1 
ATOM   9274  C C     . VAL B 2 211  ? 188.264 359.439 206.346 1.00 105.17 ? 211  VAL C C     1 
ATOM   9275  O O     . VAL B 2 211  ? 188.011 359.633 207.541 1.00 105.17 ? 211  VAL C O     1 
ATOM   9276  C CB    . VAL B 2 211  ? 187.122 357.576 205.056 1.00 105.17 ? 211  VAL C CB    1 
ATOM   9277  C CG1   . VAL B 2 211  ? 185.790 357.201 204.434 1.00 105.17 ? 211  VAL C CG1   1 
ATOM   9278  C CG2   . VAL B 2 211  ? 188.264 357.177 204.131 1.00 105.17 ? 211  VAL C CG2   1 
ATOM   9279  N N     . ASP B 2 212  ? 189.502 359.549 205.857 1.00 101.43 ? 212  ASP C N     1 
ATOM   9280  C CA    . ASP B 2 212  ? 190.594 360.014 206.703 1.00 101.43 ? 212  ASP C CA    1 
ATOM   9281  C C     . ASP B 2 212  ? 190.369 361.446 207.166 1.00 101.43 ? 212  ASP C C     1 
ATOM   9282  O O     . ASP B 2 212  ? 190.767 361.805 208.278 1.00 101.43 ? 212  ASP C O     1 
ATOM   9283  C CB    . ASP B 2 212  ? 191.925 359.897 205.959 1.00 101.43 ? 212  ASP C CB    1 
ATOM   9284  C CG    . ASP B 2 212  ? 192.432 358.470 205.892 1.00 101.43 ? 212  ASP C CG    1 
ATOM   9285  O OD1   . ASP B 2 212  ? 191.598 357.543 205.831 1.00 101.43 ? 212  ASP C OD1   1 
ATOM   9286  O OD2   . ASP B 2 212  ? 193.666 358.275 205.901 1.00 101.43 ? 212  ASP C OD2   1 
ATOM   9287  N N     . MET B 2 213  ? 189.728 362.275 206.337 1.00 101.68 ? 213  MET C N     1 
ATOM   9288  C CA    . MET B 2 213  ? 189.441 363.649 206.739 1.00 101.68 ? 213  MET C CA    1 
ATOM   9289  C C     . MET B 2 213  ? 188.505 363.683 207.942 1.00 101.68 ? 213  MET C C     1 
ATOM   9290  O O     . MET B 2 213  ? 188.785 364.353 208.948 1.00 101.68 ? 213  MET C O     1 
ATOM   9291  C CB    . MET B 2 213  ? 188.835 364.424 205.567 1.00 101.68 ? 213  MET C CB    1 
ATOM   9292  C CG    . MET B 2 213  ? 189.786 364.658 204.406 1.00 101.68 ? 213  MET C CG    1 
ATOM   9293  S SD    . MET B 2 213  ? 191.521 364.641 204.889 1.00 101.68 ? 213  MET C SD    1 
ATOM   9294  C CE    . MET B 2 213  ? 192.201 363.549 203.642 1.00 101.68 ? 213  MET C CE    1 
ATOM   9295  N N     . TRP B 2 214  ? 187.385 362.958 207.864 1.00 96.06  ? 214  TRP C N     1 
ATOM   9296  C CA    . TRP B 2 214  ? 186.477 362.945 209.006 1.00 96.06  ? 214  TRP C CA    1 
ATOM   9297  C C     . TRP B 2 214  ? 187.092 362.226 210.199 1.00 96.06  ? 214  TRP C C     1 
ATOM   9298  O O     . TRP B 2 214  ? 186.804 362.581 211.346 1.00 96.06  ? 214  TRP C O     1 
ATOM   9299  C CB    . TRP B 2 214  ? 185.133 362.309 208.652 1.00 96.06  ? 214  TRP C CB    1 
ATOM   9300  C CG    . TRP B 2 214  ? 184.034 362.792 209.566 1.00 96.06  ? 214  TRP C CG    1 
ATOM   9301  C CD1   . TRP B 2 214  ? 184.177 363.627 210.634 1.00 96.06  ? 214  TRP C CD1   1 
ATOM   9302  C CD2   . TRP B 2 214  ? 182.641 362.456 209.508 1.00 96.06  ? 214  TRP C CD2   1 
ATOM   9303  N NE1   . TRP B 2 214  ? 182.965 363.843 211.238 1.00 96.06  ? 214  TRP C NE1   1 
ATOM   9304  C CE2   . TRP B 2 214  ? 182.005 363.135 210.567 1.00 96.06  ? 214  TRP C CE2   1 
ATOM   9305  C CE3   . TRP B 2 214  ? 181.870 361.655 208.665 1.00 96.06  ? 214  TRP C CE3   1 
ATOM   9306  C CZ2   . TRP B 2 214  ? 180.637 363.036 210.804 1.00 96.06  ? 214  TRP C CZ2   1 
ATOM   9307  C CZ3   . TRP B 2 214  ? 180.511 361.557 208.906 1.00 96.06  ? 214  TRP C CZ3   1 
ATOM   9308  C CH2   . TRP B 2 214  ? 179.909 362.246 209.962 1.00 96.06  ? 214  TRP C CH2   1 
ATOM   9309  N N     . SER B 2 215  ? 187.941 361.225 209.960 1.00 91.65  ? 215  SER C N     1 
ATOM   9310  C CA    . SER B 2 215  ? 188.631 360.575 211.067 1.00 91.65  ? 215  SER C CA    1 
ATOM   9311  C C     . SER B 2 215  ? 189.535 361.561 211.797 1.00 91.65  ? 215  SER C C     1 
ATOM   9312  O O     . SER B 2 215  ? 189.565 361.596 213.031 1.00 91.65  ? 215  SER C O     1 
ATOM   9313  C CB    . SER B 2 215  ? 189.429 359.378 210.553 1.00 91.65  ? 215  SER C CB    1 
ATOM   9314  O OG    . SER B 2 215  ? 188.573 358.302 210.211 1.00 91.65  ? 215  SER C OG    1 
ATOM   9315  N N     . THR B 2 216  ? 190.269 362.385 211.044 1.00 93.52  ? 216  THR C N     1 
ATOM   9316  C CA    . THR B 2 216  ? 191.109 363.411 211.654 1.00 93.52  ? 216  THR C CA    1 
ATOM   9317  C C     . THR B 2 216  ? 190.269 364.420 212.425 1.00 93.52  ? 216  THR C C     1 
ATOM   9318  O O     . THR B 2 216  ? 190.645 364.845 213.525 1.00 93.52  ? 216  THR C O     1 
ATOM   9319  C CB    . THR B 2 216  ? 191.935 364.120 210.580 1.00 93.52  ? 216  THR C CB    1 
ATOM   9320  O OG1   . THR B 2 216  ? 192.680 363.154 209.828 1.00 93.52  ? 216  THR C OG1   1 
ATOM   9321  C CG2   . THR B 2 216  ? 192.892 365.120 211.213 1.00 93.52  ? 216  THR C CG2   1 
ATOM   9322  N N     . GLY B 2 217  ? 189.130 364.823 211.857 1.00 92.66  ? 217  GLY C N     1 
ATOM   9323  C CA    . GLY B 2 217  ? 188.241 365.722 212.578 1.00 92.66  ? 217  GLY C CA    1 
ATOM   9324  C C     . GLY B 2 217  ? 187.740 365.125 213.880 1.00 92.66  ? 217  GLY C C     1 
ATOM   9325  O O     . GLY B 2 217  ? 187.653 365.814 214.901 1.00 92.66  ? 217  GLY C O     1 
ATOM   9326  N N     . VAL B 2 218  ? 187.408 363.832 213.862 1.00 89.29  ? 218  VAL C N     1 
ATOM   9327  C CA    . VAL B 2 218  ? 186.941 363.159 215.069 1.00 89.29  ? 218  VAL C CA    1 
ATOM   9328  C C     . VAL B 2 218  ? 188.059 363.072 216.101 1.00 89.29  ? 218  VAL C C     1 
ATOM   9329  O O     . VAL B 2 218  ? 187.825 363.252 217.301 1.00 89.29  ? 218  VAL C O     1 
ATOM   9330  C CB    . VAL B 2 218  ? 186.375 361.769 214.720 1.00 89.29  ? 218  VAL C CB    1 
ATOM   9331  C CG1   . VAL B 2 218  ? 186.189 360.934 215.977 1.00 89.29  ? 218  VAL C CG1   1 
ATOM   9332  C CG2   . VAL B 2 218  ? 185.057 361.907 213.973 1.00 89.29  ? 218  VAL C CG2   1 
ATOM   9333  N N     . ILE B 2 219  ? 189.290 362.796 215.656 1.00 88.06  ? 219  ILE C N     1 
ATOM   9334  C CA    . ILE B 2 219  ? 190.426 362.786 216.578 1.00 88.06  ? 219  ILE C CA    1 
ATOM   9335  C C     . ILE B 2 219  ? 190.591 364.154 217.225 1.00 88.06  ? 219  ILE C C     1 
ATOM   9336  O O     . ILE B 2 219  ? 190.797 364.268 218.439 1.00 88.06  ? 219  ILE C O     1 
ATOM   9337  C CB    . ILE B 2 219  ? 191.717 362.354 215.858 1.00 88.06  ? 219  ILE C CB    1 
ATOM   9338  C CG1   . ILE B 2 219  ? 191.545 360.999 215.174 1.00 88.06  ? 219  ILE C CG1   1 
ATOM   9339  C CG2   . ILE B 2 219  ? 192.888 362.318 216.833 1.00 88.06  ? 219  ILE C CG2   1 
ATOM   9340  C CD1   . ILE B 2 219  ? 191.580 359.832 216.116 1.00 88.06  ? 219  ILE C CD1   1 
ATOM   9341  N N     . MET B 2 220  ? 190.504 365.214 216.417 1.00 86.57  ? 220  MET C N     1 
ATOM   9342  C CA    . MET B 2 220  ? 190.644 366.565 216.951 1.00 86.57  ? 220  MET C CA    1 
ATOM   9343  C C     . MET B 2 220  ? 189.564 366.866 217.981 1.00 86.57  ? 220  MET C C     1 
ATOM   9344  O O     . MET B 2 220  ? 189.859 367.372 219.072 1.00 86.57  ? 220  MET C O     1 
ATOM   9345  C CB    . MET B 2 220  ? 190.594 367.583 215.812 1.00 86.57  ? 220  MET C CB    1 
ATOM   9346  N N     . TYR B 2 221  ? 188.307 366.552 217.656 1.00 94.26  ? 221  TYR C N     1 
ATOM   9347  C CA    . TYR B 2 221  ? 187.211 366.828 218.579 1.00 94.26  ? 221  TYR C CA    1 
ATOM   9348  C C     . TYR B 2 221  ? 187.354 366.024 219.865 1.00 94.26  ? 221  TYR C C     1 
ATOM   9349  O O     . TYR B 2 221  ? 187.142 366.552 220.963 1.00 94.26  ? 221  TYR C O     1 
ATOM   9350  C CB    . TYR B 2 221  ? 185.870 366.534 217.904 1.00 94.26  ? 221  TYR C CB    1 
ATOM   9351  C CG    . TYR B 2 221  ? 184.688 367.219 218.554 1.00 94.26  ? 221  TYR C CG    1 
ATOM   9352  C CD1   . TYR B 2 221  ? 184.107 366.706 219.707 1.00 94.26  ? 221  TYR C CD1   1 
ATOM   9353  C CD2   . TYR B 2 221  ? 184.154 368.382 218.014 1.00 94.26  ? 221  TYR C CD2   1 
ATOM   9354  C CE1   . TYR B 2 221  ? 183.027 367.330 220.302 1.00 94.26  ? 221  TYR C CE1   1 
ATOM   9355  C CE2   . TYR B 2 221  ? 183.075 369.014 218.602 1.00 94.26  ? 221  TYR C CE2   1 
ATOM   9356  C CZ    . TYR B 2 221  ? 182.515 368.483 219.746 1.00 94.26  ? 221  TYR C CZ    1 
ATOM   9357  O OH    . TYR B 2 221  ? 181.440 369.109 220.335 1.00 94.26  ? 221  TYR C OH    1 
ATOM   9358  N N     . THR B 2 222  ? 187.719 364.744 219.750 1.00 91.96  ? 222  THR C N     1 
ATOM   9359  C CA    . THR B 2 222  ? 187.864 363.899 220.930 1.00 91.96  ? 222  THR C CA    1 
ATOM   9360  C C     . THR B 2 222  ? 189.001 364.381 221.821 1.00 91.96  ? 222  THR C C     1 
ATOM   9361  O O     . THR B 2 222  ? 188.873 364.394 223.050 1.00 91.96  ? 222  THR C O     1 
ATOM   9362  C CB    . THR B 2 222  ? 188.094 362.447 220.506 1.00 91.96  ? 222  THR C CB    1 
ATOM   9363  O OG1   . THR B 2 222  ? 186.963 361.981 219.760 1.00 91.96  ? 222  THR C OG1   1 
ATOM   9364  C CG2   . THR B 2 222  ? 188.290 361.554 221.723 1.00 91.96  ? 222  THR C CG2   1 
ATOM   9365  N N     . LEU B 2 223  ? 190.123 364.786 221.221 1.00 91.68  ? 223  LEU C N     1 
ATOM   9366  C CA    . LEU B 2 223  ? 191.266 365.209 222.022 1.00 91.68  ? 223  LEU C CA    1 
ATOM   9367  C C     . LEU B 2 223  ? 191.006 366.562 222.673 1.00 91.68  ? 223  LEU C C     1 
ATOM   9368  O O     . LEU B 2 223  ? 191.401 366.790 223.823 1.00 91.68  ? 223  LEU C O     1 
ATOM   9369  C CB    . LEU B 2 223  ? 192.527 365.241 221.152 1.00 91.68  ? 223  LEU C CB    1 
ATOM   9370  C CG    . LEU B 2 223  ? 193.921 365.462 221.759 1.00 91.68  ? 223  LEU C CG    1 
ATOM   9371  C CD1   . LEU B 2 223  ? 194.982 365.028 220.761 1.00 91.68  ? 223  LEU C CD1   1 
ATOM   9372  C CD2   . LEU B 2 223  ? 194.178 366.902 222.183 1.00 91.68  ? 223  LEU C CD2   1 
ATOM   9373  N N     . LEU B 2 224  ? 190.335 367.471 221.962 1.00 91.81  ? 224  LEU C N     1 
ATOM   9374  C CA    . LEU B 2 224  ? 190.109 368.806 222.505 1.00 91.81  ? 224  LEU C CA    1 
ATOM   9375  C C     . LEU B 2 224  ? 188.969 368.811 223.519 1.00 91.81  ? 224  LEU C C     1 
ATOM   9376  O O     . LEU B 2 224  ? 189.164 369.169 224.686 1.00 91.81  ? 224  LEU C O     1 
ATOM   9377  C CB    . LEU B 2 224  ? 189.828 369.792 221.369 1.00 91.81  ? 224  LEU C CB    1 
ATOM   9378  N N     . ALA B 2 225  ? 187.768 368.416 223.090 1.00 88.97  ? 225  ALA C N     1 
ATOM   9379  C CA    . ALA B 2 225  ? 186.614 368.436 223.983 1.00 88.97  ? 225  ALA C CA    1 
ATOM   9380  C C     . ALA B 2 225  ? 186.689 367.364 225.062 1.00 88.97  ? 225  ALA C C     1 
ATOM   9381  O O     . ALA B 2 225  ? 185.989 367.474 226.074 1.00 88.97  ? 225  ALA C O     1 
ATOM   9382  C CB    . ALA B 2 225  ? 185.324 368.271 223.178 1.00 88.97  ? 225  ALA C CB    1 
ATOM   9383  N N     . GLY B 2 226  ? 187.516 366.337 224.873 1.00 86.87  ? 226  GLY C N     1 
ATOM   9384  C CA    . GLY B 2 226  ? 187.643 365.265 225.835 1.00 86.87  ? 226  GLY C CA    1 
ATOM   9385  C C     . GLY B 2 226  ? 186.716 364.089 225.615 1.00 86.87  ? 226  GLY C C     1 
ATOM   9386  O O     . GLY B 2 226  ? 186.869 363.067 226.297 1.00 86.87  ? 226  GLY C O     1 
ATOM   9387  N N     . SER B 2 227  ? 185.764 364.196 224.694 1.00 89.96  ? 227  SER C N     1 
ATOM   9388  C CA    . SER B 2 227  ? 184.832 363.121 224.399 1.00 89.96  ? 227  SER C CA    1 
ATOM   9389  C C     . SER B 2 227  ? 184.588 363.059 222.899 1.00 89.96  ? 227  SER C C     1 
ATOM   9390  O O     . SER B 2 227  ? 184.726 364.072 222.202 1.00 89.96  ? 227  SER C O     1 
ATOM   9391  C CB    . SER B 2 227  ? 183.495 363.315 225.131 1.00 89.96  ? 227  SER C CB    1 
ATOM   9392  O OG    . SER B 2 227  ? 182.899 364.553 224.783 1.00 89.96  ? 227  SER C OG    1 
ATOM   9393  N N     . PRO B 2 228  ? 184.247 361.884 222.376 1.00 92.63  ? 228  PRO C N     1 
ATOM   9394  C CA    . PRO B 2 228  ? 183.891 361.769 220.958 1.00 92.63  ? 228  PRO C CA    1 
ATOM   9395  C C     . PRO B 2 228  ? 182.733 362.688 220.611 1.00 92.63  ? 228  PRO C C     1 
ATOM   9396  O O     . PRO B 2 228  ? 181.819 362.884 221.427 1.00 92.63  ? 228  PRO C O     1 
ATOM   9397  C CB    . PRO B 2 228  ? 183.483 360.293 220.812 1.00 92.63  ? 228  PRO C CB    1 
ATOM   9398  C CG    . PRO B 2 228  ? 183.882 359.611 222.111 1.00 92.63  ? 228  PRO C CG    1 
ATOM   9399  C CD    . PRO B 2 228  ? 184.658 360.588 222.933 1.00 92.63  ? 228  PRO C CD    1 
ATOM   9400  N N     . PRO B 2 229  ? 182.742 363.280 219.413 1.00 94.99  ? 229  PRO C N     1 
ATOM   9401  C CA    . PRO B 2 229  ? 181.632 364.168 219.029 1.00 94.99  ? 229  PRO C CA    1 
ATOM   9402  C C     . PRO B 2 229  ? 180.280 363.476 218.999 1.00 94.99  ? 229  PRO C C     1 
ATOM   9403  O O     . PRO B 2 229  ? 179.266 364.105 219.329 1.00 94.99  ? 229  PRO C O     1 
ATOM   9404  C CB    . PRO B 2 229  ? 182.045 364.661 217.635 1.00 94.99  ? 229  PRO C CB    1 
ATOM   9405  C CG    . PRO B 2 229  ? 183.003 363.631 217.131 1.00 94.99  ? 229  PRO C CG    1 
ATOM   9406  C CD    . PRO B 2 229  ? 183.737 363.132 218.338 1.00 94.99  ? 229  PRO C CD    1 
ATOM   9407  N N     . PHE B 2 230  ? 180.231 362.202 218.617 1.00 100.39 ? 230  PHE C N     1 
ATOM   9408  C CA    . PHE B 2 230  ? 178.988 361.447 218.541 1.00 100.39 ? 230  PHE C CA    1 
ATOM   9409  C C     . PHE B 2 230  ? 179.079 360.235 219.456 1.00 100.39 ? 230  PHE C C     1 
ATOM   9410  O O     . PHE B 2 230  ? 180.042 359.465 219.379 1.00 100.39 ? 230  PHE C O     1 
ATOM   9411  C CB    . PHE B 2 230  ? 178.697 361.006 217.104 1.00 100.39 ? 230  PHE C CB    1 
ATOM   9412  N N     . TRP B 2 231  ? 178.076 360.069 220.316 1.00 100.73 ? 231  TRP C N     1 
ATOM   9413  C CA    . TRP B 2 231  ? 178.033 358.946 221.242 1.00 100.73 ? 231  TRP C CA    1 
ATOM   9414  C C     . TRP B 2 231  ? 176.611 358.784 221.756 1.00 100.73 ? 231  TRP C C     1 
ATOM   9415  O O     . TRP B 2 231  ? 175.939 359.774 222.054 1.00 100.73 ? 231  TRP C O     1 
ATOM   9416  C CB    . TRP B 2 231  ? 179.000 359.151 222.415 1.00 100.73 ? 231  TRP C CB    1 
ATOM   9417  C CG    . TRP B 2 231  ? 178.528 358.531 223.694 1.00 100.73 ? 231  TRP C CG    1 
ATOM   9418  C CD1   . TRP B 2 231  ? 178.016 359.181 224.780 1.00 100.73 ? 231  TRP C CD1   1 
ATOM   9419  C CD2   . TRP B 2 231  ? 178.518 357.136 224.020 1.00 100.73 ? 231  TRP C CD2   1 
ATOM   9420  N NE1   . TRP B 2 231  ? 177.691 358.277 225.762 1.00 100.73 ? 231  TRP C NE1   1 
ATOM   9421  C CE2   . TRP B 2 231  ? 177.989 357.015 225.321 1.00 100.73 ? 231  TRP C CE2   1 
ATOM   9422  C CE3   . TRP B 2 231  ? 178.906 355.978 223.339 1.00 100.73 ? 231  TRP C CE3   1 
ATOM   9423  C CZ2   . TRP B 2 231  ? 177.838 355.783 225.953 1.00 100.73 ? 231  TRP C CZ2   1 
ATOM   9424  C CZ3   . TRP B 2 231  ? 178.755 354.756 223.969 1.00 100.73 ? 231  TRP C CZ3   1 
ATOM   9425  C CH2   . TRP B 2 231  ? 178.226 354.668 225.262 1.00 100.73 ? 231  TRP C CH2   1 
ATOM   9426  N N     . HIS B 2 232  ? 176.165 357.534 221.858 1.00 102.41 ? 232  HIS C N     1 
ATOM   9427  C CA    . HIS B 2 232  ? 174.841 357.232 222.383 1.00 102.41 ? 232  HIS C CA    1 
ATOM   9428  C C     . HIS B 2 232  ? 174.832 355.792 222.873 1.00 102.41 ? 232  HIS C C     1 
ATOM   9429  O O     . HIS B 2 232  ? 175.683 354.983 222.494 1.00 102.41 ? 232  HIS C O     1 
ATOM   9430  C CB    . HIS B 2 232  ? 173.751 357.456 221.330 1.00 102.41 ? 232  HIS C CB    1 
ATOM   9431  C CG    . HIS B 2 232  ? 172.490 358.047 221.880 1.00 102.41 ? 232  HIS C CG    1 
ATOM   9432  N ND1   . HIS B 2 232  ? 172.023 357.761 223.145 1.00 102.41 ? 232  HIS C ND1   1 
ATOM   9433  C CD2   . HIS B 2 232  ? 171.600 358.911 221.337 1.00 102.41 ? 232  HIS C CD2   1 
ATOM   9434  C CE1   . HIS B 2 232  ? 170.899 358.422 223.357 1.00 102.41 ? 232  HIS C CE1   1 
ATOM   9435  N NE2   . HIS B 2 232  ? 170.620 359.128 222.276 1.00 102.41 ? 232  HIS C NE2   1 
ATOM   9436  N N     . ARG B 2 233  ? 173.856 355.484 223.728 1.00 101.19 ? 233  ARG C N     1 
ATOM   9437  C CA    . ARG B 2 233  ? 173.728 354.138 224.272 1.00 101.19 ? 233  ARG C CA    1 
ATOM   9438  C C     . ARG B 2 233  ? 173.149 353.146 223.273 1.00 101.19 ? 233  ARG C C     1 
ATOM   9439  O O     . ARG B 2 233  ? 173.187 351.939 223.535 1.00 101.19 ? 233  ARG C O     1 
ATOM   9440  C CB    . ARG B 2 233  ? 172.863 354.163 225.534 1.00 101.19 ? 233  ARG C CB    1 
ATOM   9441  N N     . LYS B 2 234  ? 172.619 353.615 222.146 1.00 107.59 ? 234  LYS C N     1 
ATOM   9442  C CA    . LYS B 2 234  ? 172.014 352.758 221.137 1.00 107.59 ? 234  LYS C CA    1 
ATOM   9443  C C     . LYS B 2 234  ? 172.822 352.839 219.850 1.00 107.59 ? 234  LYS C C     1 
ATOM   9444  O O     . LYS B 2 234  ? 173.299 353.917 219.480 1.00 107.59 ? 234  LYS C O     1 
ATOM   9445  C CB    . LYS B 2 234  ? 170.559 353.158 220.875 1.00 107.59 ? 234  LYS C CB    1 
ATOM   9446  N N     . GLN B 2 235  ? 172.979 351.697 219.178 1.00 110.68 ? 235  GLN C N     1 
ATOM   9447  C CA    . GLN B 2 235  ? 173.700 351.670 217.909 1.00 110.68 ? 235  GLN C CA    1 
ATOM   9448  C C     . GLN B 2 235  ? 172.988 352.510 216.856 1.00 110.68 ? 235  GLN C C     1 
ATOM   9449  O O     . GLN B 2 235  ? 173.592 353.389 216.229 1.00 110.68 ? 235  GLN C O     1 
ATOM   9450  C CB    . GLN B 2 235  ? 173.847 350.225 217.424 1.00 110.68 ? 235  GLN C CB    1 
ATOM   9451  C CG    . GLN B 2 235  ? 175.106 349.478 217.873 1.00 110.68 ? 235  GLN C CG    1 
ATOM   9452  C CD    . GLN B 2 235  ? 176.331 350.362 218.019 1.00 110.68 ? 235  GLN C CD    1 
ATOM   9453  O OE1   . GLN B 2 235  ? 176.507 351.043 219.029 1.00 110.68 ? 235  GLN C OE1   1 
ATOM   9454  N NE2   . GLN B 2 235  ? 177.188 350.354 217.004 1.00 110.68 ? 235  GLN C NE2   1 
ATOM   9455  N N     . MET B 2 236  ? 171.691 352.257 216.660 1.00 109.00 ? 236  MET C N     1 
ATOM   9456  C CA    . MET B 2 236  ? 170.949 352.918 215.591 1.00 109.00 ? 236  MET C CA    1 
ATOM   9457  C C     . MET B 2 236  ? 170.842 354.419 215.827 1.00 109.00 ? 236  MET C C     1 
ATOM   9458  O O     . MET B 2 236  ? 170.925 355.208 214.879 1.00 109.00 ? 236  MET C O     1 
ATOM   9459  C CB    . MET B 2 236  ? 169.559 352.296 215.457 1.00 109.00 ? 236  MET C CB    1 
ATOM   9460  N N     . LEU B 2 237  ? 170.650 354.832 217.081 1.00 107.17 ? 237  LEU C N     1 
ATOM   9461  C CA    . LEU B 2 237  ? 170.489 356.252 217.377 1.00 107.17 ? 237  LEU C CA    1 
ATOM   9462  C C     . LEU B 2 237  ? 171.739 357.039 216.999 1.00 107.17 ? 237  LEU C C     1 
ATOM   9463  O O     . LEU B 2 237  ? 171.663 358.039 216.273 1.00 107.17 ? 237  LEU C O     1 
ATOM   9464  C CB    . LEU B 2 237  ? 170.156 356.444 218.857 1.00 107.17 ? 237  LEU C CB    1 
ATOM   9465  N N     . MET B 2 238  ? 172.907 356.593 217.468 1.00 105.73 ? 238  MET C N     1 
ATOM   9466  C CA    . MET B 2 238  ? 174.131 357.317 217.147 1.00 105.73 ? 238  MET C CA    1 
ATOM   9467  C C     . MET B 2 238  ? 174.520 357.142 215.685 1.00 105.73 ? 238  MET C C     1 
ATOM   9468  O O     . MET B 2 238  ? 175.138 358.041 215.106 1.00 105.73 ? 238  MET C O     1 
ATOM   9469  C CB    . MET B 2 238  ? 175.272 356.885 218.072 1.00 105.73 ? 238  MET C CB    1 
ATOM   9470  C CG    . MET B 2 238  ? 176.285 355.937 217.456 1.00 105.73 ? 238  MET C CG    1 
ATOM   9471  S SD    . MET B 2 238  ? 177.546 355.449 218.646 1.00 105.73 ? 238  MET C SD    1 
ATOM   9472  C CE    . MET B 2 238  ? 176.695 354.138 219.515 1.00 105.73 ? 238  MET C CE    1 
ATOM   9473  N N     . LEU B 2 239  ? 174.160 356.013 215.066 1.00 105.05 ? 239  LEU C N     1 
ATOM   9474  C CA    . LEU B 2 239  ? 174.402 355.858 213.634 1.00 105.05 ? 239  LEU C CA    1 
ATOM   9475  C C     . LEU B 2 239  ? 173.610 356.886 212.834 1.00 105.05 ? 239  LEU C C     1 
ATOM   9476  O O     . LEU B 2 239  ? 174.144 357.530 211.923 1.00 105.05 ? 239  LEU C O     1 
ATOM   9477  C CB    . LEU B 2 239  ? 174.052 354.437 213.190 1.00 105.05 ? 239  LEU C CB    1 
ATOM   9478  C CG    . LEU B 2 239  ? 175.208 353.440 213.056 1.00 105.05 ? 239  LEU C CG    1 
ATOM   9479  C CD1   . LEU B 2 239  ? 175.973 353.686 211.765 1.00 105.05 ? 239  LEU C CD1   1 
ATOM   9480  C CD2   . LEU B 2 239  ? 176.145 353.507 214.253 1.00 105.05 ? 239  LEU C CD2   1 
ATOM   9481  N N     . ARG B 2 240  ? 172.333 357.067 213.176 1.00 98.45  ? 240  ARG C N     1 
ATOM   9482  C CA    . ARG B 2 240  ? 171.527 358.086 212.513 1.00 98.45  ? 240  ARG C CA    1 
ATOM   9483  C C     . ARG B 2 240  ? 172.063 359.482 212.803 1.00 98.45  ? 240  ARG C C     1 
ATOM   9484  O O     . ARG B 2 240  ? 172.067 360.349 211.921 1.00 98.45  ? 240  ARG C O     1 
ATOM   9485  C CB    . ARG B 2 240  ? 170.067 357.968 212.950 1.00 98.45  ? 240  ARG C CB    1 
ATOM   9486  N N     . MET B 2 241  ? 172.518 359.717 214.037 1.00 98.88  ? 241  MET C N     1 
ATOM   9487  C CA    . MET B 2 241  ? 173.061 361.026 214.386 1.00 98.88  ? 241  MET C CA    1 
ATOM   9488  C C     . MET B 2 241  ? 174.307 361.352 213.568 1.00 98.88  ? 241  MET C C     1 
ATOM   9489  O O     . MET B 2 241  ? 174.446 362.468 213.056 1.00 98.88  ? 241  MET C O     1 
ATOM   9490  C CB    . MET B 2 241  ? 173.372 361.082 215.882 1.00 98.88  ? 241  MET C CB    1 
ATOM   9491  N N     . ILE B 2 242  ? 175.224 360.391 213.431 1.00 97.44  ? 242  ILE C N     1 
ATOM   9492  C CA    . ILE B 2 242  ? 176.455 360.655 212.691 1.00 97.44  ? 242  ILE C CA    1 
ATOM   9493  C C     . ILE B 2 242  ? 176.168 360.744 211.195 1.00 97.44  ? 242  ILE C C     1 
ATOM   9494  O O     . ILE B 2 242  ? 176.817 361.510 210.472 1.00 97.44  ? 242  ILE C O     1 
ATOM   9495  C CB    . ILE B 2 242  ? 177.529 359.596 213.016 1.00 97.44  ? 242  ILE C CB    1 
ATOM   9496  C CG1   . ILE B 2 242  ? 178.832 359.906 212.280 1.00 97.44  ? 242  ILE C CG1   1 
ATOM   9497  C CG2   . ILE B 2 242  ? 177.068 358.205 212.635 1.00 97.44  ? 242  ILE C CG2   1 
ATOM   9498  C CD1   . ILE B 2 242  ? 179.926 358.888 212.521 1.00 97.44  ? 242  ILE C CD1   1 
ATOM   9499  N N     . MET B 2 243  ? 175.192 359.972 210.705 1.00 98.59  ? 243  MET C N     1 
ATOM   9500  C CA    . MET B 2 243  ? 174.809 360.078 209.300 1.00 98.59  ? 243  MET C CA    1 
ATOM   9501  C C     . MET B 2 243  ? 174.208 361.444 208.993 1.00 98.59  ? 243  MET C C     1 
ATOM   9502  O O     . MET B 2 243  ? 174.488 362.033 207.942 1.00 98.59  ? 243  MET C O     1 
ATOM   9503  C CB    . MET B 2 243  ? 173.827 358.964 208.939 1.00 98.59  ? 243  MET C CB    1 
ATOM   9504  N N     . SER B 2 244  ? 173.376 361.965 209.899 1.00 98.07  ? 244  SER C N     1 
ATOM   9505  C CA    . SER B 2 244  ? 172.747 363.261 209.677 1.00 98.07  ? 244  SER C CA    1 
ATOM   9506  C C     . SER B 2 244  ? 173.724 364.419 209.833 1.00 98.07  ? 244  SER C C     1 
ATOM   9507  O O     . SER B 2 244  ? 173.463 365.506 209.307 1.00 98.07  ? 244  SER C O     1 
ATOM   9508  C CB    . SER B 2 244  ? 171.568 363.444 210.635 1.00 98.07  ? 244  SER C CB    1 
ATOM   9509  O OG    . SER B 2 244  ? 172.005 363.459 211.983 1.00 98.07  ? 244  SER C OG    1 
ATOM   9510  N N     . GLY B 2 245  ? 174.836 364.213 210.535 1.00 97.55  ? 245  GLY C N     1 
ATOM   9511  C CA    . GLY B 2 245  ? 175.807 365.269 210.742 1.00 97.55  ? 245  GLY C CA    1 
ATOM   9512  C C     . GLY B 2 245  ? 175.272 366.424 211.564 1.00 97.55  ? 245  GLY C C     1 
ATOM   9513  O O     . GLY B 2 245  ? 175.475 367.590 211.215 1.00 97.55  ? 245  GLY C O     1 
ATOM   9514  N N     . ASN B 2 246  ? 174.587 366.110 212.662 1.00 102.27 ? 246  ASN C N     1 
ATOM   9515  C CA    . ASN B 2 246  ? 173.986 367.114 213.538 1.00 102.27 ? 246  ASN C CA    1 
ATOM   9516  C C     . ASN B 2 246  ? 174.828 367.359 214.783 1.00 102.27 ? 246  ASN C C     1 
ATOM   9517  O O     . ASN B 2 246  ? 174.295 367.615 215.867 1.00 102.27 ? 246  ASN C O     1 
ATOM   9518  C CB    . ASN B 2 246  ? 172.568 366.699 213.921 1.00 102.27 ? 246  ASN C CB    1 
ATOM   9519  C CG    . ASN B 2 246  ? 172.532 365.413 214.725 1.00 102.27 ? 246  ASN C CG    1 
ATOM   9520  O OD1   . ASN B 2 246  ? 173.452 364.599 214.657 1.00 102.27 ? 246  ASN C OD1   1 
ATOM   9521  N ND2   . ASN B 2 246  ? 171.465 365.226 215.493 1.00 102.27 ? 246  ASN C ND2   1 
ATOM   9522  N N     . TYR B 2 247  ? 176.150 367.285 214.653 1.00 103.85 ? 247  TYR C N     1 
ATOM   9523  C CA    . TYR B 2 247  ? 177.035 367.522 215.784 1.00 103.85 ? 247  TYR C CA    1 
ATOM   9524  C C     . TYR B 2 247  ? 176.930 368.968 216.257 1.00 103.85 ? 247  TYR C C     1 
ATOM   9525  O O     . TYR B 2 247  ? 176.654 369.884 215.478 1.00 103.85 ? 247  TYR C O     1 
ATOM   9526  C CB    . TYR B 2 247  ? 178.481 367.196 215.406 1.00 103.85 ? 247  TYR C CB    1 
ATOM   9527  C CG    . TYR B 2 247  ? 179.192 368.313 214.673 1.00 103.85 ? 247  TYR C CG    1 
ATOM   9528  C CD1   . TYR B 2 247  ? 179.022 368.488 213.306 1.00 103.85 ? 247  TYR C CD1   1 
ATOM   9529  C CD2   . TYR B 2 247  ? 180.027 369.195 215.348 1.00 103.85 ? 247  TYR C CD2   1 
ATOM   9530  C CE1   . TYR B 2 247  ? 179.666 369.507 212.631 1.00 103.85 ? 247  TYR C CE1   1 
ATOM   9531  C CE2   . TYR B 2 247  ? 180.672 370.219 214.682 1.00 103.85 ? 247  TYR C CE2   1 
ATOM   9532  C CZ    . TYR B 2 247  ? 180.489 370.369 213.324 1.00 103.85 ? 247  TYR C CZ    1 
ATOM   9533  O OH    . TYR B 2 247  ? 181.131 371.385 212.655 1.00 103.85 ? 247  TYR C OH    1 
ATOM   9534  N N     . GLN B 2 248  ? 177.153 369.165 217.554 1.00 105.95 ? 248  GLN C N     1 
ATOM   9535  C CA    . GLN B 2 248  ? 177.098 370.483 218.164 1.00 105.95 ? 248  GLN C CA    1 
ATOM   9536  C C     . GLN B 2 248  ? 178.287 370.667 219.095 1.00 105.95 ? 248  GLN C C     1 
ATOM   9537  O O     . GLN B 2 248  ? 178.850 369.702 219.620 1.00 105.95 ? 248  GLN C O     1 
ATOM   9538  C CB    . GLN B 2 248  ? 175.787 370.693 218.937 1.00 105.95 ? 248  GLN C CB    1 
ATOM   9539  N N     . PHE B 2 249  ? 178.666 371.926 219.293 1.00 108.23 ? 249  PHE C N     1 
ATOM   9540  C CA    . PHE B 2 249  ? 179.759 372.288 220.184 1.00 108.23 ? 249  PHE C CA    1 
ATOM   9541  C C     . PHE B 2 249  ? 179.209 372.537 221.582 1.00 108.23 ? 249  PHE C C     1 
ATOM   9542  O O     . PHE B 2 249  ? 178.189 373.216 221.741 1.00 108.23 ? 249  PHE C O     1 
ATOM   9543  C CB    . PHE B 2 249  ? 180.492 373.531 219.674 1.00 108.23 ? 249  PHE C CB    1 
ATOM   9544  C CG    . PHE B 2 249  ? 181.480 373.246 218.578 1.00 108.23 ? 249  PHE C CG    1 
ATOM   9545  C CD1   . PHE B 2 249  ? 182.794 372.929 218.878 1.00 108.23 ? 249  PHE C CD1   1 
ATOM   9546  C CD2   . PHE B 2 249  ? 181.097 373.300 217.249 1.00 108.23 ? 249  PHE C CD2   1 
ATOM   9547  C CE1   . PHE B 2 249  ? 183.708 372.668 217.874 1.00 108.23 ? 249  PHE C CE1   1 
ATOM   9548  C CE2   . PHE B 2 249  ? 182.006 373.040 216.239 1.00 108.23 ? 249  PHE C CE2   1 
ATOM   9549  C CZ    . PHE B 2 249  ? 183.313 372.723 216.553 1.00 108.23 ? 249  PHE C CZ    1 
ATOM   9550  N N     . GLY B 2 250  ? 179.881 371.979 222.586 1.00 116.79 ? 250  GLY C N     1 
ATOM   9551  C CA    . GLY B 2 250  ? 179.436 372.175 223.956 1.00 116.79 ? 250  GLY C CA    1 
ATOM   9552  C C     . GLY B 2 250  ? 179.519 373.636 224.362 1.00 116.79 ? 250  GLY C C     1 
ATOM   9553  O O     . GLY B 2 250  ? 180.434 374.363 223.968 1.00 116.79 ? 250  GLY C O     1 
ATOM   9554  N N     . SER B 2 251  ? 178.539 374.069 225.168 1.00 118.00 ? 251  SER C N     1 
ATOM   9555  C CA    . SER B 2 251  ? 178.507 375.470 225.591 1.00 118.00 ? 251  SER C CA    1 
ATOM   9556  C C     . SER B 2 251  ? 179.589 375.790 226.617 1.00 118.00 ? 251  SER C C     1 
ATOM   9557  O O     . SER B 2 251  ? 180.384 376.717 226.382 1.00 118.00 ? 251  SER C O     1 
ATOM   9558  C CB    . SER B 2 251  ? 177.107 375.833 226.092 1.00 118.00 ? 251  SER C CB    1 
ATOM   9559  O OG    . SER B 2 251  ? 176.824 377.203 225.866 1.00 118.00 ? 251  SER C OG    1 
ATOM   9560  N N     . PRO B 2 252  ? 179.691 375.089 227.754 1.00 117.09 ? 252  PRO C N     1 
ATOM   9561  C CA    . PRO B 2 252  ? 180.686 375.487 228.759 1.00 117.09 ? 252  PRO C CA    1 
ATOM   9562  C C     . PRO B 2 252  ? 182.089 374.964 228.495 1.00 117.09 ? 252  PRO C C     1 
ATOM   9563  O O     . PRO B 2 252  ? 183.016 375.346 229.222 1.00 117.09 ? 252  PRO C O     1 
ATOM   9564  C CB    . PRO B 2 252  ? 180.120 374.902 230.058 1.00 117.09 ? 252  PRO C CB    1 
ATOM   9565  C CG    . PRO B 2 252  ? 179.337 373.709 229.628 1.00 117.09 ? 252  PRO C CG    1 
ATOM   9566  C CD    . PRO B 2 252  ? 178.970 373.870 228.171 1.00 117.09 ? 252  PRO C CD    1 
ATOM   9567  N N     . GLU B 2 253  ? 182.279 374.111 227.490 1.00 112.21 ? 253  GLU C N     1 
ATOM   9568  C CA    . GLU B 2 253  ? 183.590 373.557 227.174 1.00 112.21 ? 253  GLU C CA    1 
ATOM   9569  C C     . GLU B 2 253  ? 184.299 374.303 226.051 1.00 112.21 ? 253  GLU C C     1 
ATOM   9570  O O     . GLU B 2 253  ? 185.503 374.556 226.147 1.00 112.21 ? 253  GLU C O     1 
ATOM   9571  C CB    . GLU B 2 253  ? 183.463 372.077 226.799 1.00 112.21 ? 253  GLU C CB    1 
ATOM   9572  N N     . TRP B 2 254  ? 183.580 374.659 224.990 1.00 112.60 ? 254  TRP C N     1 
ATOM   9573  C CA    . TRP B 2 254  ? 184.155 375.357 223.848 1.00 112.60 ? 254  TRP C CA    1 
ATOM   9574  C C     . TRP B 2 254  ? 184.095 376.874 223.977 1.00 112.60 ? 254  TRP C C     1 
ATOM   9575  O O     . TRP B 2 254  ? 184.575 377.573 223.078 1.00 112.60 ? 254  TRP C O     1 
ATOM   9576  C CB    . TRP B 2 254  ? 183.445 374.928 222.559 1.00 112.60 ? 254  TRP C CB    1 
ATOM   9577  C CG    . TRP B 2 254  ? 183.737 373.521 222.141 1.00 112.60 ? 254  TRP C CG    1 
ATOM   9578  C CD1   . TRP B 2 254  ? 182.891 372.453 222.207 1.00 112.60 ? 254  TRP C CD1   1 
ATOM   9579  C CD2   . TRP B 2 254  ? 184.950 373.035 221.552 1.00 112.60 ? 254  TRP C CD2   1 
ATOM   9580  N NE1   . TRP B 2 254  ? 183.508 371.328 221.716 1.00 112.60 ? 254  TRP C NE1   1 
ATOM   9581  C CE2   . TRP B 2 254  ? 184.773 371.660 221.306 1.00 112.60 ? 254  TRP C CE2   1 
ATOM   9582  C CE3   . TRP B 2 254  ? 186.171 373.629 221.218 1.00 112.60 ? 254  TRP C CE3   1 
ATOM   9583  C CZ2   . TRP B 2 254  ? 185.770 370.869 220.740 1.00 112.60 ? 254  TRP C CZ2   1 
ATOM   9584  C CZ3   . TRP B 2 254  ? 187.159 372.842 220.658 1.00 112.60 ? 254  TRP C CZ3   1 
ATOM   9585  C CH2   . TRP B 2 254  ? 186.952 371.477 220.423 1.00 112.60 ? 254  TRP C CH2   1 
ATOM   9586  N N     . ASP B 2 255  ? 183.515 377.399 225.059 1.00 117.83 ? 255  ASP C N     1 
ATOM   9587  C CA    . ASP B 2 255  ? 183.421 378.848 225.211 1.00 117.83 ? 255  ASP C CA    1 
ATOM   9588  C C     . ASP B 2 255  ? 184.799 379.484 225.349 1.00 117.83 ? 255  ASP C C     1 
ATOM   9589  O O     . ASP B 2 255  ? 185.074 380.525 224.741 1.00 117.83 ? 255  ASP C O     1 
ATOM   9590  C CB    . ASP B 2 255  ? 182.547 379.196 226.417 1.00 117.83 ? 255  ASP C CB    1 
ATOM   9591  C CG    . ASP B 2 255  ? 182.875 378.359 227.638 1.00 117.83 ? 255  ASP C CG    1 
ATOM   9592  O OD1   . ASP B 2 255  ? 183.881 377.619 227.604 1.00 117.83 ? 255  ASP C OD1   1 
ATOM   9593  O OD2   . ASP B 2 255  ? 182.128 378.445 228.635 1.00 117.83 ? 255  ASP C OD2   1 
ATOM   9594  N N     . ASP B 2 256  ? 185.678 378.875 226.139 1.00 121.76 ? 256  ASP C N     1 
ATOM   9595  C CA    . ASP B 2 256  ? 187.022 379.407 226.364 1.00 121.76 ? 256  ASP C CA    1 
ATOM   9596  C C     . ASP B 2 256  ? 188.035 378.802 225.395 1.00 121.76 ? 256  ASP C C     1 
ATOM   9597  O O     . ASP B 2 256  ? 189.076 378.283 225.793 1.00 121.76 ? 256  ASP C O     1 
ATOM   9598  C CB    . ASP B 2 256  ? 187.436 379.168 227.811 1.00 121.76 ? 256  ASP C CB    1 
ATOM   9599  C CG    . ASP B 2 256  ? 188.588 380.055 228.242 1.00 121.76 ? 256  ASP C CG    1 
ATOM   9600  O OD1   . ASP B 2 256  ? 188.493 381.287 228.059 1.00 121.76 ? 256  ASP C OD1   1 
ATOM   9601  O OD2   . ASP B 2 256  ? 189.588 379.520 228.766 1.00 121.76 ? 256  ASP C OD2   1 
ATOM   9602  N N     . TYR B 2 257  ? 187.730 378.873 224.100 1.00 113.81 ? 257  TYR C N     1 
ATOM   9603  C CA    . TYR B 2 257  ? 188.606 378.351 223.062 1.00 113.81 ? 257  TYR C CA    1 
ATOM   9604  C C     . TYR B 2 257  ? 188.641 379.325 221.894 1.00 113.81 ? 257  TYR C C     1 
ATOM   9605  O O     . TYR B 2 257  ? 187.718 380.120 221.700 1.00 113.81 ? 257  TYR C O     1 
ATOM   9606  C CB    . TYR B 2 257  ? 188.153 376.966 222.577 1.00 113.81 ? 257  TYR C CB    1 
ATOM   9607  C CG    . TYR B 2 257  ? 189.027 375.828 223.057 1.00 113.81 ? 257  TYR C CG    1 
ATOM   9608  C CD1   . TYR B 2 257  ? 189.115 375.513 224.407 1.00 113.81 ? 257  TYR C CD1   1 
ATOM   9609  C CD2   . TYR B 2 257  ? 189.768 375.070 222.159 1.00 113.81 ? 257  TYR C CD2   1 
ATOM   9610  C CE1   . TYR B 2 257  ? 189.914 374.474 224.849 1.00 113.81 ? 257  TYR C CE1   1 
ATOM   9611  C CE2   . TYR B 2 257  ? 190.570 374.030 222.591 1.00 113.81 ? 257  TYR C CE2   1 
ATOM   9612  C CZ    . TYR B 2 257  ? 190.639 373.737 223.937 1.00 113.81 ? 257  TYR C CZ    1 
ATOM   9613  O OH    . TYR B 2 257  ? 191.435 372.703 224.372 1.00 113.81 ? 257  TYR C OH    1 
ATOM   9614  N N     . SER B 2 258  ? 189.720 379.256 221.120 1.00 108.83 ? 258  SER C N     1 
ATOM   9615  C CA    . SER B 2 258  ? 189.877 380.133 219.970 1.00 108.83 ? 258  SER C CA    1 
ATOM   9616  C C     . SER B 2 258  ? 188.935 379.723 218.842 1.00 108.83 ? 258  SER C C     1 
ATOM   9617  O O     . SER B 2 258  ? 188.486 378.577 218.758 1.00 108.83 ? 258  SER C O     1 
ATOM   9618  C CB    . SER B 2 258  ? 191.323 380.115 219.476 1.00 108.83 ? 258  SER C CB    1 
ATOM   9619  O OG    . SER B 2 258  ? 191.530 381.096 218.475 1.00 108.83 ? 258  SER C OG    1 
ATOM   9620  N N     . ASP B 2 259  ? 188.627 380.687 217.972 1.00 106.72 ? 259  ASP C N     1 
ATOM   9621  C CA    . ASP B 2 259  ? 187.745 380.421 216.842 1.00 106.72 ? 259  ASP C CA    1 
ATOM   9622  C C     . ASP B 2 259  ? 188.452 379.679 215.715 1.00 106.72 ? 259  ASP C C     1 
ATOM   9623  O O     . ASP B 2 259  ? 187.794 378.977 214.936 1.00 106.72 ? 259  ASP C O     1 
ATOM   9624  C CB    . ASP B 2 259  ? 187.156 381.731 216.317 1.00 106.72 ? 259  ASP C CB    1 
ATOM   9625  C CG    . ASP B 2 259  ? 185.688 381.609 215.962 1.00 106.72 ? 259  ASP C CG    1 
ATOM   9626  O OD1   . ASP B 2 259  ? 184.955 380.910 216.693 1.00 106.72 ? 259  ASP C OD1   1 
ATOM   9627  O OD2   . ASP B 2 259  ? 185.266 382.212 214.953 1.00 106.72 ? 259  ASP C OD2   1 
ATOM   9628  N N     . THR B 2 260  ? 189.776 379.829 215.601 1.00 105.17 ? 260  THR C N     1 
ATOM   9629  C CA    . THR B 2 260  ? 190.495 379.202 214.496 1.00 105.17 ? 260  THR C CA    1 
ATOM   9630  C C     . THR B 2 260  ? 190.407 377.680 214.564 1.00 105.17 ? 260  THR C C     1 
ATOM   9631  O O     . THR B 2 260  ? 190.109 377.021 213.558 1.00 105.17 ? 260  THR C O     1 
ATOM   9632  C CB    . THR B 2 260  ? 191.954 379.676 214.472 1.00 105.17 ? 260  THR C CB    1 
ATOM   9633  O OG1   . THR B 2 260  ? 192.669 378.992 213.434 1.00 105.17 ? 260  THR C OG1   1 
ATOM   9634  C CG2   . THR B 2 260  ? 192.645 379.456 215.816 1.00 105.17 ? 260  THR C CG2   1 
ATOM   9635  N N     . VAL B 2 261  ? 190.622 377.106 215.750 1.00 100.79 ? 261  VAL C N     1 
ATOM   9636  C CA    . VAL B 2 261  ? 190.495 375.661 215.905 1.00 100.79 ? 261  VAL C CA    1 
ATOM   9637  C C     . VAL B 2 261  ? 189.050 375.234 215.691 1.00 100.79 ? 261  VAL C C     1 
ATOM   9638  O O     . VAL B 2 261  ? 188.781 374.161 215.139 1.00 100.79 ? 261  VAL C O     1 
ATOM   9639  C CB    . VAL B 2 261  ? 191.027 375.216 217.280 1.00 100.79 ? 261  VAL C CB    1 
ATOM   9640  C CG1   . VAL B 2 261  ? 192.543 375.300 217.311 1.00 100.79 ? 261  VAL C CG1   1 
ATOM   9641  C CG2   . VAL B 2 261  ? 190.427 376.065 218.388 1.00 100.79 ? 261  VAL C CG2   1 
ATOM   9642  N N     . LYS B 2 262  ? 188.099 376.073 216.110 1.00 101.80 ? 262  LYS C N     1 
ATOM   9643  C CA    . LYS B 2 262  ? 186.690 375.735 215.938 1.00 101.80 ? 262  LYS C CA    1 
ATOM   9644  C C     . LYS B 2 262  ? 186.326 375.606 214.464 1.00 101.80 ? 262  LYS C C     1 
ATOM   9645  O O     . LYS B 2 262  ? 185.712 374.612 214.056 1.00 101.80 ? 262  LYS C O     1 
ATOM   9646  C CB    . LYS B 2 262  ? 185.811 376.787 216.614 1.00 101.80 ? 262  LYS C CB    1 
ATOM   9647  C CG    . LYS B 2 262  ? 184.337 376.416 216.662 1.00 101.80 ? 262  LYS C CG    1 
ATOM   9648  C CD    . LYS B 2 262  ? 183.456 377.651 216.720 1.00 101.80 ? 262  LYS C CD    1 
ATOM   9649  C CE    . LYS B 2 262  ? 183.299 378.274 215.344 1.00 101.80 ? 262  LYS C CE    1 
ATOM   9650  N NZ    . LYS B 2 262  ? 182.934 377.259 214.317 1.00 101.80 ? 262  LYS C NZ    1 
ATOM   9651  N N     . ASP B 2 263  ? 186.708 376.589 213.643 1.00 102.07 ? 263  ASP C N     1 
ATOM   9652  C CA    . ASP B 2 263  ? 186.335 376.517 212.233 1.00 102.07 ? 263  ASP C CA    1 
ATOM   9653  C C     . ASP B 2 263  ? 187.162 375.468 211.499 1.00 102.07 ? 263  ASP C C     1 
ATOM   9654  O O     . ASP B 2 263  ? 186.674 374.845 210.549 1.00 102.07 ? 263  ASP C O     1 
ATOM   9655  C CB    . ASP B 2 263  ? 186.458 377.883 211.552 1.00 102.07 ? 263  ASP C CB    1 
ATOM   9656  C CG    . ASP B 2 263  ? 187.890 378.300 211.319 1.00 102.07 ? 263  ASP C CG    1 
ATOM   9657  O OD1   . ASP B 2 263  ? 188.500 378.859 212.246 1.00 102.07 ? 263  ASP C OD1   1 
ATOM   9658  O OD2   . ASP B 2 263  ? 188.393 378.107 210.193 1.00 102.07 ? 263  ASP C OD2   1 
ATOM   9659  N N     . LEU B 2 264  ? 188.408 375.238 211.931 1.00 99.92  ? 264  LEU C N     1 
ATOM   9660  C CA    . LEU B 2 264  ? 189.180 374.143 211.351 1.00 99.92  ? 264  LEU C CA    1 
ATOM   9661  C C     . LEU B 2 264  ? 188.504 372.801 211.609 1.00 99.92  ? 264  LEU C C     1 
ATOM   9662  O O     . LEU B 2 264  ? 188.379 371.971 210.699 1.00 99.92  ? 264  LEU C O     1 
ATOM   9663  C CB    . LEU B 2 264  ? 190.604 374.150 211.910 1.00 99.92  ? 264  LEU C CB    1 
ATOM   9664  C CG    . LEU B 2 264  ? 191.550 373.040 211.444 1.00 99.92  ? 264  LEU C CG    1 
ATOM   9665  C CD1   . LEU B 2 264  ? 192.913 373.611 211.095 1.00 99.92  ? 264  LEU C CD1   1 
ATOM   9666  C CD2   . LEU B 2 264  ? 191.686 371.962 212.510 1.00 99.92  ? 264  LEU C CD2   1 
ATOM   9667  N N     . VAL B 2 265  ? 188.042 372.581 212.842 1.00 95.75  ? 265  VAL C N     1 
ATOM   9668  C CA    . VAL B 2 265  ? 187.341 371.345 213.172 1.00 95.75  ? 265  VAL C CA    1 
ATOM   9669  C C     . VAL B 2 265  ? 186.046 371.240 212.377 1.00 95.75  ? 265  VAL C C     1 
ATOM   9670  O O     . VAL B 2 265  ? 185.715 370.176 211.840 1.00 95.75  ? 265  VAL C O     1 
ATOM   9671  C CB    . VAL B 2 265  ? 187.090 371.271 214.691 1.00 95.75  ? 265  VAL C CB    1 
ATOM   9672  C CG1   . VAL B 2 265  ? 185.967 370.301 215.008 1.00 95.75  ? 265  VAL C CG1   1 
ATOM   9673  C CG2   . VAL B 2 265  ? 188.367 370.876 215.420 1.00 95.75  ? 265  VAL C CG2   1 
ATOM   9674  N N     . SER B 2 266  ? 185.301 372.345 212.272 1.00 98.13  ? 266  SER C N     1 
ATOM   9675  C CA    . SER B 2 266  ? 184.045 372.325 211.527 1.00 98.13  ? 266  SER C CA    1 
ATOM   9676  C C     . SER B 2 266  ? 184.275 371.975 210.062 1.00 98.13  ? 266  SER C C     1 
ATOM   9677  O O     . SER B 2 266  ? 183.503 371.213 209.469 1.00 98.13  ? 266  SER C O     1 
ATOM   9678  C CB    . SER B 2 266  ? 183.338 373.675 211.648 1.00 98.13  ? 266  SER C CB    1 
ATOM   9679  O OG    . SER B 2 266  ? 184.008 374.669 210.893 1.00 98.13  ? 266  SER C OG    1 
ATOM   9680  N N     . ARG B 2 267  ? 185.330 372.529 209.458 1.00 99.49  ? 267  ARG C N     1 
ATOM   9681  C CA    . ARG B 2 267  ? 185.670 372.170 208.086 1.00 99.49  ? 267  ARG C CA    1 
ATOM   9682  C C     . ARG B 2 267  ? 186.092 370.709 207.991 1.00 99.49  ? 267  ARG C C     1 
ATOM   9683  O O     . ARG B 2 267  ? 185.840 370.046 206.978 1.00 99.49  ? 267  ARG C O     1 
ATOM   9684  C CB    . ARG B 2 267  ? 186.779 373.084 207.563 1.00 99.49  ? 267  ARG C CB    1 
ATOM   9685  C CG    . ARG B 2 267  ? 186.290 374.377 206.919 1.00 99.49  ? 267  ARG C CG    1 
ATOM   9686  C CD    . ARG B 2 267  ? 185.177 374.131 205.907 1.00 99.49  ? 267  ARG C CD    1 
ATOM   9687  N NE    . ARG B 2 267  ? 183.850 374.326 206.480 1.00 99.49  ? 267  ARG C NE    1 
ATOM   9688  C CZ    . ARG B 2 267  ? 183.309 375.508 206.741 1.00 99.49  ? 267  ARG C CZ    1 
ATOM   9689  N NH1   . ARG B 2 267  ? 183.951 376.635 206.482 1.00 99.49  ? 267  ARG C NH1   1 
ATOM   9690  N NH2   . ARG B 2 267  ? 182.092 375.561 207.275 1.00 99.49  ? 267  ARG C NH2   1 
ATOM   9691  N N     . PHE B 2 268  ? 186.740 370.190 209.037 1.00 93.68  ? 268  PHE C N     1 
ATOM   9692  C CA    . PHE B 2 268  ? 187.145 368.789 209.032 1.00 93.68  ? 268  PHE C CA    1 
ATOM   9693  C C     . PHE B 2 268  ? 185.977 367.838 209.270 1.00 93.68  ? 268  PHE C C     1 
ATOM   9694  O O     . PHE B 2 268  ? 186.119 366.635 209.027 1.00 93.68  ? 268  PHE C O     1 
ATOM   9695  C CB    . PHE B 2 268  ? 188.231 368.551 210.083 1.00 93.68  ? 268  PHE C CB    1 
ATOM   9696  C CG    . PHE B 2 268  ? 189.618 368.465 209.511 1.00 93.68  ? 268  PHE C CG    1 
ATOM   9697  C CD1   . PHE B 2 268  ? 189.908 367.567 208.497 1.00 93.68  ? 268  PHE C CD1   1 
ATOM   9698  C CD2   . PHE B 2 268  ? 190.630 369.281 209.988 1.00 93.68  ? 268  PHE C CD2   1 
ATOM   9699  C CE1   . PHE B 2 268  ? 191.183 367.485 207.969 1.00 93.68  ? 268  PHE C CE1   1 
ATOM   9700  C CE2   . PHE B 2 268  ? 191.907 369.203 209.464 1.00 93.68  ? 268  PHE C CE2   1 
ATOM   9701  C CZ    . PHE B 2 268  ? 192.184 368.304 208.453 1.00 93.68  ? 268  PHE C CZ    1 
ATOM   9702  N N     . LEU B 2 269  ? 184.833 368.339 209.736 1.00 96.24  ? 269  LEU C N     1 
ATOM   9703  C CA    . LEU B 2 269  ? 183.663 367.509 209.992 1.00 96.24  ? 269  LEU C CA    1 
ATOM   9704  C C     . LEU B 2 269  ? 182.550 367.723 208.972 1.00 96.24  ? 269  LEU C C     1 
ATOM   9705  O O     . LEU B 2 269  ? 181.389 367.425 209.268 1.00 96.24  ? 269  LEU C O     1 
ATOM   9706  C CB    . LEU B 2 269  ? 183.121 367.764 211.401 1.00 96.24  ? 269  LEU C CB    1 
ATOM   9707  C CG    . LEU B 2 269  ? 184.061 367.632 212.603 1.00 96.24  ? 269  LEU C CG    1 
ATOM   9708  C CD1   . LEU B 2 269  ? 183.363 368.107 213.866 1.00 96.24  ? 269  LEU C CD1   1 
ATOM   9709  C CD2   . LEU B 2 269  ? 184.571 366.216 212.776 1.00 96.24  ? 269  LEU C CD2   1 
ATOM   9710  N N     . VAL B 2 270  ? 182.874 368.239 207.784 1.00 99.74  ? 270  VAL C N     1 
ATOM   9711  C CA    . VAL B 2 270  ? 181.851 368.503 206.778 1.00 99.74  ? 270  VAL C CA    1 
ATOM   9712  C C     . VAL B 2 270  ? 181.261 367.186 206.292 1.00 99.74  ? 270  VAL C C     1 
ATOM   9713  O O     . VAL B 2 270  ? 181.987 366.224 206.014 1.00 99.74  ? 270  VAL C O     1 
ATOM   9714  C CB    . VAL B 2 270  ? 182.443 369.323 205.622 1.00 99.74  ? 270  VAL C CB    1 
ATOM   9715  C CG1   . VAL B 2 270  ? 181.519 369.298 204.415 1.00 99.74  ? 270  VAL C CG1   1 
ATOM   9716  C CG2   . VAL B 2 270  ? 182.706 370.753 206.068 1.00 99.74  ? 270  VAL C CG2   1 
ATOM   9717  N N     . VAL B 2 271  ? 179.929 367.133 206.203 1.00 101.69 ? 271  VAL C N     1 
ATOM   9718  C CA    . VAL B 2 271  ? 179.263 365.906 205.771 1.00 101.69 ? 271  VAL C CA    1 
ATOM   9719  C C     . VAL B 2 271  ? 179.514 365.646 204.288 1.00 101.69 ? 271  VAL C C     1 
ATOM   9720  O O     . VAL B 2 271  ? 179.653 364.492 203.862 1.00 101.69 ? 271  VAL C O     1 
ATOM   9721  C CB    . VAL B 2 271  ? 177.758 365.964 206.107 1.00 101.69 ? 271  VAL C CB    1 
ATOM   9722  C CG1   . VAL B 2 271  ? 177.027 366.973 205.228 1.00 101.69 ? 271  VAL C CG1   1 
ATOM   9723  C CG2   . VAL B 2 271  ? 177.132 364.583 205.976 1.00 101.69 ? 271  VAL C CG2   1 
ATOM   9724  N N     . GLN B 2 272  ? 179.578 366.699 203.482 1.00 105.89 ? 272  GLN C N     1 
ATOM   9725  C CA    . GLN B 2 272  ? 179.767 366.537 202.044 1.00 105.89 ? 272  GLN C CA    1 
ATOM   9726  C C     . GLN B 2 272  ? 181.235 366.273 201.733 1.00 105.89 ? 272  GLN C C     1 
ATOM   9727  O O     . GLN B 2 272  ? 182.086 367.107 202.064 1.00 105.89 ? 272  GLN C O     1 
ATOM   9728  C CB    . GLN B 2 272  ? 179.284 367.780 201.303 1.00 105.89 ? 272  GLN C CB    1 
ATOM   9729  N N     . PRO B 2 273  ? 181.577 365.145 201.102 1.00 108.09 ? 273  PRO C N     1 
ATOM   9730  C CA    . PRO B 2 273  ? 182.995 364.866 200.819 1.00 108.09 ? 273  PRO C CA    1 
ATOM   9731  C C     . PRO B 2 273  ? 183.655 365.899 199.922 1.00 108.09 ? 273  PRO C C     1 
ATOM   9732  O O     . PRO B 2 273  ? 184.854 366.164 200.078 1.00 108.09 ? 273  PRO C O     1 
ATOM   9733  C CB    . PRO B 2 273  ? 182.952 363.483 200.153 1.00 108.09 ? 273  PRO C CB    1 
ATOM   9734  C CG    . PRO B 2 273  ? 181.564 363.362 199.612 1.00 108.09 ? 273  PRO C CG    1 
ATOM   9735  C CD    . PRO B 2 273  ? 180.687 364.095 200.581 1.00 108.09 ? 273  PRO C CD    1 
ATOM   9736  N N     . GLN B 2 274  ? 182.912 366.486 198.981 1.00 110.56 ? 274  GLN C N     1 
ATOM   9737  C CA    . GLN B 2 274  ? 183.496 367.488 198.095 1.00 110.56 ? 274  GLN C CA    1 
ATOM   9738  C C     . GLN B 2 274  ? 183.915 368.735 198.866 1.00 110.56 ? 274  GLN C C     1 
ATOM   9739  O O     . GLN B 2 274  ? 184.978 369.309 198.603 1.00 110.56 ? 274  GLN C O     1 
ATOM   9740  C CB    . GLN B 2 274  ? 182.507 367.849 196.987 1.00 110.56 ? 274  GLN C CB    1 
ATOM   9741  N N     . ASN B 2 275  ? 183.093 369.168 199.823 1.00 108.86 ? 275  ASN C N     1 
ATOM   9742  C CA    . ASN B 2 275  ? 183.375 370.379 200.582 1.00 108.86 ? 275  ASN C CA    1 
ATOM   9743  C C     . ASN B 2 275  ? 184.391 370.169 201.697 1.00 108.86 ? 275  ASN C C     1 
ATOM   9744  O O     . ASN B 2 275  ? 184.856 371.156 202.278 1.00 108.86 ? 275  ASN C O     1 
ATOM   9745  C CB    . ASN B 2 275  ? 182.078 370.941 201.172 1.00 108.86 ? 275  ASN C CB    1 
ATOM   9746  N N     . ARG B 2 276  ? 184.741 368.924 202.013 1.00 108.39 ? 276  ARG C N     1 
ATOM   9747  C CA    . ARG B 2 276  ? 185.720 368.666 203.062 1.00 108.39 ? 276  ARG C CA    1 
ATOM   9748  C C     . ARG B 2 276  ? 187.098 369.163 202.645 1.00 108.39 ? 276  ARG C C     1 
ATOM   9749  O O     . ARG B 2 276  ? 187.527 368.966 201.504 1.00 108.39 ? 276  ARG C O     1 
ATOM   9750  C CB    . ARG B 2 276  ? 185.764 367.173 203.386 1.00 108.39 ? 276  ARG C CB    1 
ATOM   9751  C CG    . ARG B 2 276  ? 184.485 366.656 204.019 1.00 108.39 ? 276  ARG C CG    1 
ATOM   9752  C CD    . ARG B 2 276  ? 184.676 365.304 204.685 1.00 108.39 ? 276  ARG C CD    1 
ATOM   9753  N NE    . ARG B 2 276  ? 184.018 364.245 203.930 1.00 108.39 ? 276  ARG C NE    1 
ATOM   9754  C CZ    . ARG B 2 276  ? 183.625 363.087 204.443 1.00 108.39 ? 276  ARG C CZ    1 
ATOM   9755  N NH1   . ARG B 2 276  ? 183.801 362.804 205.722 1.00 108.39 ? 276  ARG C NH1   1 
ATOM   9756  N NH2   . ARG B 2 276  ? 183.038 362.193 203.653 1.00 108.39 ? 276  ARG C NH2   1 
ATOM   9757  N N     . TYR B 2 277  ? 187.787 369.814 203.578 1.00 113.25 ? 277  TYR C N     1 
ATOM   9758  C CA    . TYR B 2 277  ? 189.107 370.361 203.298 1.00 113.25 ? 277  TYR C CA    1 
ATOM   9759  C C     . TYR B 2 277  ? 190.119 369.244 203.079 1.00 113.25 ? 277  TYR C C     1 
ATOM   9760  O O     . TYR B 2 277  ? 190.116 368.231 203.786 1.00 113.25 ? 277  TYR C O     1 
ATOM   9761  C CB    . TYR B 2 277  ? 189.560 371.262 204.446 1.00 113.25 ? 277  TYR C CB    1 
ATOM   9762  C CG    . TYR B 2 277  ? 189.480 372.740 204.138 1.00 113.25 ? 277  TYR C CG    1 
ATOM   9763  C CD1   . TYR B 2 277  ? 188.409 373.264 203.426 1.00 113.25 ? 277  TYR C CD1   1 
ATOM   9764  C CD2   . TYR B 2 277  ? 190.474 373.612 204.564 1.00 113.25 ? 277  TYR C CD2   1 
ATOM   9765  C CE1   . TYR B 2 277  ? 188.332 374.614 203.144 1.00 113.25 ? 277  TYR C CE1   1 
ATOM   9766  C CE2   . TYR B 2 277  ? 190.405 374.964 204.286 1.00 113.25 ? 277  TYR C CE2   1 
ATOM   9767  C CZ    . TYR B 2 277  ? 189.332 375.459 203.576 1.00 113.25 ? 277  TYR C CZ    1 
ATOM   9768  O OH    . TYR B 2 277  ? 189.259 376.805 203.298 1.00 113.25 ? 277  TYR C OH    1 
ATOM   9769  N N     . THR B 2 278  ? 190.989 369.433 202.092 1.00 114.44 ? 278  THR C N     1 
ATOM   9770  C CA    . THR B 2 278  ? 192.046 368.473 201.822 1.00 114.44 ? 278  THR C CA    1 
ATOM   9771  C C     . THR B 2 278  ? 193.218 368.693 202.776 1.00 114.44 ? 278  THR C C     1 
ATOM   9772  O O     . THR B 2 278  ? 193.253 369.648 203.557 1.00 114.44 ? 278  THR C O     1 
ATOM   9773  C CB    . THR B 2 278  ? 192.513 368.579 200.370 1.00 114.44 ? 278  THR C CB    1 
ATOM   9774  O OG1   . THR B 2 278  ? 193.584 367.654 200.143 1.00 114.44 ? 278  THR C OG1   1 
ATOM   9775  C CG2   . THR B 2 278  ? 192.996 369.989 200.068 1.00 114.44 ? 278  THR C CG2   1 
ATOM   9776  N N     . ALA B 2 279  ? 194.189 367.778 202.712 1.00 112.63 ? 279  ALA C N     1 
ATOM   9777  C CA    . ALA B 2 279  ? 195.362 367.885 203.573 1.00 112.63 ? 279  ALA C CA    1 
ATOM   9778  C C     . ALA B 2 279  ? 196.164 369.143 203.267 1.00 112.63 ? 279  ALA C C     1 
ATOM   9779  O O     . ALA B 2 279  ? 196.581 369.861 204.184 1.00 112.63 ? 279  ALA C O     1 
ATOM   9780  C CB    . ALA B 2 279  ? 196.238 366.642 203.423 1.00 112.63 ? 279  ALA C CB    1 
ATOM   9781  N N     . GLU B 2 280  ? 196.380 369.432 201.980 1.00 115.84 ? 280  GLU C N     1 
ATOM   9782  C CA    . GLU B 2 280  ? 197.182 370.592 201.601 1.00 115.84 ? 280  GLU C CA    1 
ATOM   9783  C C     . GLU B 2 280  ? 196.533 371.889 202.067 1.00 115.84 ? 280  GLU C C     1 
ATOM   9784  O O     . GLU B 2 280  ? 197.222 372.806 202.529 1.00 115.84 ? 280  GLU C O     1 
ATOM   9785  C CB    . GLU B 2 280  ? 197.396 370.610 200.088 1.00 115.84 ? 280  GLU C CB    1 
ATOM   9786  C CG    . GLU B 2 280  ? 198.440 371.612 199.623 1.00 115.84 ? 280  GLU C CG    1 
ATOM   9787  C CD    . GLU B 2 280  ? 198.220 372.060 198.192 1.00 115.84 ? 280  GLU C CD    1 
ATOM   9788  O OE1   . GLU B 2 280  ? 198.071 371.188 197.310 1.00 115.84 ? 280  GLU C OE1   1 
ATOM   9789  O OE2   . GLU B 2 280  ? 198.197 373.285 197.948 1.00 115.84 ? 280  GLU C OE2   1 
ATOM   9790  N N     . GLU B 2 281  ? 195.207 371.988 201.945 1.00 113.51 ? 281  GLU C N     1 
ATOM   9791  C CA    . GLU B 2 281  ? 194.505 373.158 202.463 1.00 113.51 ? 281  GLU C CA    1 
ATOM   9792  C C     . GLU B 2 281  ? 194.646 373.255 203.976 1.00 113.51 ? 281  GLU C C     1 
ATOM   9793  O O     . GLU B 2 281  ? 194.749 374.356 204.529 1.00 113.51 ? 281  GLU C O     1 
ATOM   9794  C CB    . GLU B 2 281  ? 193.031 373.107 202.061 1.00 113.51 ? 281  GLU C CB    1 
ATOM   9795  N N     . ALA B 2 282  ? 194.645 372.110 204.663 1.00 113.94 ? 282  ALA C N     1 
ATOM   9796  C CA    . ALA B 2 282  ? 194.817 372.115 206.112 1.00 113.94 ? 282  ALA C CA    1 
ATOM   9797  C C     . ALA B 2 282  ? 196.196 372.633 206.505 1.00 113.94 ? 282  ALA C C     1 
ATOM   9798  O O     . ALA B 2 282  ? 196.329 373.382 207.479 1.00 113.94 ? 282  ALA C O     1 
ATOM   9799  C CB    . ALA B 2 282  ? 194.586 370.715 206.675 1.00 113.94 ? 282  ALA C CB    1 
ATOM   9800  N N     . LEU B 2 283  ? 197.238 372.237 205.768 1.00 115.33 ? 283  LEU C N     1 
ATOM   9801  C CA    . LEU B 2 283  ? 198.567 372.781 206.042 1.00 115.33 ? 283  LEU C CA    1 
ATOM   9802  C C     . LEU B 2 283  ? 198.610 374.283 205.784 1.00 115.33 ? 283  LEU C C     1 
ATOM   9803  O O     . LEU B 2 283  ? 199.307 375.022 206.490 1.00 115.33 ? 283  LEU C O     1 
ATOM   9804  C CB    . LEU B 2 283  ? 199.636 372.066 205.212 1.00 115.33 ? 283  LEU C CB    1 
ATOM   9805  C CG    . LEU B 2 283  ? 199.490 370.586 204.854 1.00 115.33 ? 283  LEU C CG    1 
ATOM   9806  C CD1   . LEU B 2 283  ? 200.716 370.103 204.094 1.00 115.33 ? 283  LEU C CD1   1 
ATOM   9807  C CD2   . LEU B 2 283  ? 199.277 369.740 206.103 1.00 115.33 ? 283  LEU C CD2   1 
ATOM   9808  N N     . ALA B 2 284  ? 197.875 374.752 204.775 1.00 117.30 ? 284  ALA C N     1 
ATOM   9809  C CA    . ALA B 2 284  ? 197.828 376.175 204.461 1.00 117.30 ? 284  ALA C CA    1 
ATOM   9810  C C     . ALA B 2 284  ? 197.031 376.987 205.474 1.00 117.30 ? 284  ALA C C     1 
ATOM   9811  O O     . ALA B 2 284  ? 197.046 378.220 205.399 1.00 117.30 ? 284  ALA C O     1 
ATOM   9812  C CB    . ALA B 2 284  ? 197.244 376.383 203.063 1.00 117.30 ? 284  ALA C CB    1 
ATOM   9813  N N     . HIS B 2 285  ? 196.337 376.334 206.403 1.00 120.33 ? 285  HIS C N     1 
ATOM   9814  C CA    . HIS B 2 285  ? 195.513 377.041 207.370 1.00 120.33 ? 285  HIS C CA    1 
ATOM   9815  C C     . HIS B 2 285  ? 196.392 377.903 208.279 1.00 120.33 ? 285  HIS C C     1 
ATOM   9816  O O     . HIS B 2 285  ? 197.538 377.546 208.570 1.00 120.33 ? 285  HIS C O     1 
ATOM   9817  C CB    . HIS B 2 285  ? 194.709 376.043 208.202 1.00 120.33 ? 285  HIS C CB    1 
ATOM   9818  C CG    . HIS B 2 285  ? 193.531 376.643 208.902 1.00 120.33 ? 285  HIS C CG    1 
ATOM   9819  N ND1   . HIS B 2 285  ? 193.471 376.789 210.271 1.00 120.33 ? 285  HIS C ND1   1 
ATOM   9820  C CD2   . HIS B 2 285  ? 192.361 377.128 208.421 1.00 120.33 ? 285  HIS C CD2   1 
ATOM   9821  C CE1   . HIS B 2 285  ? 192.320 377.345 210.603 1.00 120.33 ? 285  HIS C CE1   1 
ATOM   9822  N NE2   . HIS B 2 285  ? 191.628 377.561 209.499 1.00 120.33 ? 285  HIS C NE2   1 
ATOM   9823  N N     . PRO B 2 286  ? 195.887 379.053 208.733 1.00 125.38 ? 286  PRO C N     1 
ATOM   9824  C CA    . PRO B 2 286  ? 196.689 379.903 209.630 1.00 125.38 ? 286  PRO C CA    1 
ATOM   9825  C C     . PRO B 2 286  ? 197.064 379.239 210.945 1.00 125.38 ? 286  PRO C C     1 
ATOM   9826  O O     . PRO B 2 286  ? 197.971 379.726 211.630 1.00 125.38 ? 286  PRO C O     1 
ATOM   9827  C CB    . PRO B 2 286  ? 195.785 381.122 209.855 1.00 125.38 ? 286  PRO C CB    1 
ATOM   9828  C CG    . PRO B 2 286  ? 194.893 381.149 208.671 1.00 125.38 ? 286  PRO C CG    1 
ATOM   9829  C CD    . PRO B 2 286  ? 194.651 379.724 208.295 1.00 125.38 ? 286  PRO C CD    1 
ATOM   9830  N N     . PHE B 2 287  ? 196.392 378.153 211.327 1.00 124.69 ? 287  PHE C N     1 
ATOM   9831  C CA    . PHE B 2 287  ? 196.751 377.459 212.557 1.00 124.69 ? 287  PHE C CA    1 
ATOM   9832  C C     . PHE B 2 287  ? 198.177 376.915 212.482 1.00 124.69 ? 287  PHE C C     1 
ATOM   9833  O O     . PHE B 2 287  ? 198.947 377.032 213.442 1.00 124.69 ? 287  PHE C O     1 
ATOM   9834  C CB    . PHE B 2 287  ? 195.745 376.334 212.812 1.00 124.69 ? 287  PHE C CB    1 
ATOM   9835  C CG    . PHE B 2 287  ? 195.874 375.672 214.157 1.00 124.69 ? 287  PHE C CG    1 
ATOM   9836  C CD1   . PHE B 2 287  ? 196.568 376.276 215.193 1.00 124.69 ? 287  PHE C CD1   1 
ATOM   9837  C CD2   . PHE B 2 287  ? 195.242 374.463 214.398 1.00 124.69 ? 287  PHE C CD2   1 
ATOM   9838  C CE1   . PHE B 2 287  ? 196.667 375.666 216.429 1.00 124.69 ? 287  PHE C CE1   1 
ATOM   9839  C CE2   . PHE B 2 287  ? 195.338 373.846 215.630 1.00 124.69 ? 287  PHE C CE2   1 
ATOM   9840  C CZ    . PHE B 2 287  ? 196.049 374.451 216.649 1.00 124.69 ? 287  PHE C CZ    1 
ATOM   9841  N N     . PHE B 2 288  ? 198.553 376.334 211.342 1.00 126.44 ? 288  PHE C N     1 
ATOM   9842  C CA    . PHE B 2 288  ? 199.832 375.645 211.228 1.00 126.44 ? 288  PHE C CA    1 
ATOM   9843  C C     . PHE B 2 288  ? 200.972 376.497 210.676 1.00 126.44 ? 288  PHE C C     1 
ATOM   9844  O O     . PHE B 2 288  ? 202.114 376.027 210.674 1.00 126.44 ? 288  PHE C O     1 
ATOM   9845  C CB    . PHE B 2 288  ? 199.688 374.387 210.364 1.00 126.44 ? 288  PHE C CB    1 
ATOM   9846  C CG    . PHE B 2 288  ? 198.653 373.423 210.862 1.00 126.44 ? 288  PHE C CG    1 
ATOM   9847  C CD1   . PHE B 2 288  ? 199.002 372.441 211.773 1.00 126.44 ? 288  PHE C CD1   1 
ATOM   9848  C CD2   . PHE B 2 288  ? 197.344 373.475 210.410 1.00 126.44 ? 288  PHE C CD2   1 
ATOM   9849  C CE1   . PHE B 2 288  ? 198.067 371.540 212.241 1.00 126.44 ? 288  PHE C CE1   1 
ATOM   9850  C CE2   . PHE B 2 288  ? 196.400 372.570 210.873 1.00 126.44 ? 288  PHE C CE2   1 
ATOM   9851  C CZ    . PHE B 2 288  ? 196.764 371.602 211.790 1.00 126.44 ? 288  PHE C CZ    1 
ATOM   9852  N N     . GLN B 2 289  ? 200.719 377.724 210.218 1.00 143.43 ? 289  GLN C N     1 
ATOM   9853  C CA    . GLN B 2 289  ? 201.806 378.542 209.693 1.00 143.43 ? 289  GLN C CA    1 
ATOM   9854  C C     . GLN B 2 289  ? 202.588 379.172 210.838 1.00 143.43 ? 289  GLN C C     1 
ATOM   9855  O O     . GLN B 2 289  ? 202.044 379.432 211.915 1.00 143.43 ? 289  GLN C O     1 
ATOM   9856  C CB    . GLN B 2 289  ? 201.297 379.636 208.748 1.00 143.43 ? 289  GLN C CB    1 
ATOM   9857  C CG    . GLN B 2 289  ? 200.794 380.914 209.418 1.00 143.43 ? 289  GLN C CG    1 
ATOM   9858  C CD    . GLN B 2 289  ? 199.820 381.688 208.548 1.00 143.43 ? 289  GLN C CD    1 
ATOM   9859  O OE1   . GLN B 2 289  ? 198.983 381.108 207.862 1.00 143.43 ? 289  GLN C OE1   1 
ATOM   9860  N NE2   . GLN B 2 289  ? 199.941 383.010 208.560 1.00 143.43 ? 289  GLN C NE2   1 
ATOM   9861  N N     . GLN B 2 290  ? 203.879 379.392 210.606 1.00 162.35 ? 290  GLN C N     1 
ATOM   9862  C CA    . GLN B 2 290  ? 204.746 380.036 211.580 1.00 162.35 ? 290  GLN C CA    1 
ATOM   9863  C C     . GLN B 2 290  ? 205.667 381.010 210.860 1.00 162.35 ? 290  GLN C C     1 
ATOM   9864  O O     . GLN B 2 290  ? 205.974 380.838 209.677 1.00 162.35 ? 290  GLN C O     1 
ATOM   9865  C CB    . GLN B 2 290  ? 205.557 379.001 212.378 1.00 162.35 ? 290  GLN C CB    1 
ATOM   9866  C CG    . GLN B 2 290  ? 206.696 378.359 211.599 1.00 162.35 ? 290  GLN C CG    1 
ATOM   9867  C CD    . GLN B 2 290  ? 207.414 377.270 212.380 1.00 162.35 ? 290  GLN C CD    1 
ATOM   9868  O OE1   . GLN B 2 290  ? 207.072 376.977 213.527 1.00 162.35 ? 290  GLN C OE1   1 
ATOM   9869  N NE2   . GLN B 2 290  ? 208.402 376.647 211.748 1.00 162.35 ? 290  GLN C NE2   1 
ATOM   9870  N N     . TYR B 2 291  ? 206.098 382.045 211.581 1.00 158.53 ? 291  TYR C N     1 
ATOM   9871  C CA    . TYR B 2 291  ? 206.989 383.057 211.030 1.00 158.53 ? 291  TYR C CA    1 
ATOM   9872  C C     . TYR B 2 291  ? 208.181 383.247 211.955 1.00 158.53 ? 291  TYR C C     1 
ATOM   9873  O O     . TYR B 2 291  ? 208.041 383.212 213.181 1.00 158.53 ? 291  TYR C O     1 
ATOM   9874  C CB    . TYR B 2 291  ? 206.257 384.397 210.814 1.00 158.53 ? 291  TYR C CB    1 
ATOM   9875  C CG    . TYR B 2 291  ? 206.271 385.333 212.006 1.00 158.53 ? 291  TYR C CG    1 
ATOM   9876  C CD1   . TYR B 2 291  ? 205.492 385.074 213.126 1.00 158.53 ? 291  TYR C CD1   1 
ATOM   9877  C CD2   . TYR B 2 291  ? 207.051 386.484 212.003 1.00 158.53 ? 291  TYR C CD2   1 
ATOM   9878  C CE1   . TYR B 2 291  ? 205.498 385.927 214.214 1.00 158.53 ? 291  TYR C CE1   1 
ATOM   9879  C CE2   . TYR B 2 291  ? 207.063 387.343 213.087 1.00 158.53 ? 291  TYR C CE2   1 
ATOM   9880  C CZ    . TYR B 2 291  ? 206.285 387.060 214.189 1.00 158.53 ? 291  TYR C CZ    1 
ATOM   9881  O OH    . TYR B 2 291  ? 206.294 387.913 215.269 1.00 158.53 ? 291  TYR C OH    1 
ATOM   9882  N N     . LEU B 2 292  ? 209.359 383.427 211.359 1.00 152.38 ? 292  LEU C N     1 
ATOM   9883  C CA    . LEU B 2 292  ? 210.593 383.663 212.098 1.00 152.38 ? 292  LEU C CA    1 
ATOM   9884  C C     . LEU B 2 292  ? 211.062 385.106 212.006 1.00 152.38 ? 292  LEU C C     1 
ATOM   9885  O O     . LEU B 2 292  ? 211.250 385.764 213.034 1.00 152.38 ? 292  LEU C O     1 
ATOM   9886  C CB    . LEU B 2 292  ? 211.698 382.724 211.592 1.00 152.38 ? 292  LEU C CB    1 
ATOM   9887  C CG    . LEU B 2 292  ? 211.419 381.220 211.661 1.00 152.38 ? 292  LEU C CG    1 
ATOM   9888  C CD1   . LEU B 2 292  ? 212.711 380.433 211.522 1.00 152.38 ? 292  LEU C CD1   1 
ATOM   9889  C CD2   . LEU B 2 292  ? 210.710 380.858 212.958 1.00 152.38 ? 292  LEU C CD2   1 
ATOM   9890  N N     . VAL B 2 293  ? 211.248 385.618 210.790 1.00 152.43 ? 293  VAL C N     1 
ATOM   9891  C CA    . VAL B 2 293  ? 211.660 387.000 210.581 1.00 152.43 ? 293  VAL C CA    1 
ATOM   9892  C C     . VAL B 2 293  ? 211.365 387.361 209.134 1.00 152.43 ? 293  VAL C C     1 
ATOM   9893  O O     . VAL B 2 293  ? 211.466 386.520 208.236 1.00 152.43 ? 293  VAL C O     1 
ATOM   9894  C CB    . VAL B 2 293  ? 213.154 387.207 210.943 1.00 152.43 ? 293  VAL C CB    1 
ATOM   9895  C CG1   . VAL B 2 293  ? 214.065 386.576 209.899 1.00 152.43 ? 293  VAL C CG1   1 
ATOM   9896  C CG2   . VAL B 2 293  ? 213.464 388.687 211.105 1.00 152.43 ? 293  VAL C CG2   1 
ATOM   9897  N N     . GLU B 2 294  ? 210.975 388.615 208.912 1.00 161.16 ? 294  GLU C N     1 
ATOM   9898  C CA    . GLU B 2 294  ? 210.686 389.114 207.576 1.00 161.16 ? 294  GLU C CA    1 
ATOM   9899  C C     . GLU B 2 294  ? 211.078 390.582 207.506 1.00 161.16 ? 294  GLU C C     1 
ATOM   9900  O O     . GLU B 2 294  ? 211.066 391.291 208.516 1.00 161.16 ? 294  GLU C O     1 
ATOM   9901  C CB    . GLU B 2 294  ? 209.205 388.941 207.210 1.00 161.16 ? 294  GLU C CB    1 
ATOM   9902  C CG    . GLU B 2 294  ? 208.811 387.523 206.821 1.00 161.16 ? 294  GLU C CG    1 
ATOM   9903  C CD    . GLU B 2 294  ? 208.171 387.450 205.448 1.00 161.16 ? 294  GLU C CD    1 
ATOM   9904  O OE1   . GLU B 2 294  ? 207.505 388.428 205.050 1.00 161.16 ? 294  GLU C OE1   1 
ATOM   9905  O OE2   . GLU B 2 294  ? 208.333 386.415 204.767 1.00 161.16 ? 294  GLU C OE2   1 
ATOM   9906  N N     . GLU B 2 295  ? 211.426 391.033 206.300 1.00 165.73 ? 295  GLU C N     1 
ATOM   9907  C CA    . GLU B 2 295  ? 211.839 392.413 206.078 1.00 165.73 ? 295  GLU C CA    1 
ATOM   9908  C C     . GLU B 2 295  ? 211.077 393.083 204.941 1.00 165.73 ? 295  GLU C C     1 
ATOM   9909  O O     . GLU B 2 295  ? 211.463 394.178 204.513 1.00 165.73 ? 295  GLU C O     1 
ATOM   9910  C CB    . GLU B 2 295  ? 213.345 392.480 205.807 1.00 165.73 ? 295  GLU C CB    1 
ATOM   9911  C CG    . GLU B 2 295  ? 214.199 392.508 207.064 1.00 165.73 ? 295  GLU C CG    1 
ATOM   9912  C CD    . GLU B 2 295  ? 214.492 391.121 207.599 1.00 165.73 ? 295  GLU C CD    1 
ATOM   9913  O OE1   . GLU B 2 295  ? 214.327 390.142 206.841 1.00 165.73 ? 295  GLU C OE1   1 
ATOM   9914  O OE2   . GLU B 2 295  ? 214.886 391.008 208.779 1.00 165.73 ? 295  GLU C OE2   1 
ATOM   9915  N N     . VAL B 2 296  ? 210.010 392.462 204.440 1.00 164.86 ? 296  VAL C N     1 
ATOM   9916  C CA    . VAL B 2 296  ? 209.224 393.028 203.350 1.00 164.86 ? 296  VAL C CA    1 
ATOM   9917  C C     . VAL B 2 296  ? 207.954 393.706 203.855 1.00 164.86 ? 296  VAL C C     1 
ATOM   9918  O O     . VAL B 2 296  ? 207.077 394.044 203.054 1.00 164.86 ? 296  VAL C O     1 
ATOM   9919  C CB    . VAL B 2 296  ? 208.890 391.961 202.296 1.00 164.86 ? 296  VAL C CB    1 
ATOM   9920  C CG1   . VAL B 2 296  ? 210.160 391.467 201.620 1.00 164.86 ? 296  VAL C CG1   1 
ATOM   9921  C CG2   . VAL B 2 296  ? 208.132 390.807 202.931 1.00 164.86 ? 296  VAL C CG2   1 
ATOM   9922  N N     . ARG B 2 297  ? 207.834 393.915 205.166 1.00 162.08 ? 297  ARG C N     1 
ATOM   9923  C CA    . ARG B 2 297  ? 206.658 394.563 205.748 1.00 162.08 ? 297  ARG C CA    1 
ATOM   9924  C C     . ARG B 2 297  ? 206.828 396.076 205.636 1.00 162.08 ? 297  ARG C C     1 
ATOM   9925  O O     . ARG B 2 297  ? 207.136 396.781 206.600 1.00 162.08 ? 297  ARG C O     1 
ATOM   9926  C CB    . ARG B 2 297  ? 206.459 394.122 207.192 1.00 162.08 ? 297  ARG C CB    1 
ATOM   9927  C CG    . ARG B 2 297  ? 205.857 392.734 207.341 1.00 162.08 ? 297  ARG C CG    1 
ATOM   9928  C CD    . ARG B 2 297  ? 206.828 391.774 208.012 1.00 162.08 ? 297  ARG C CD    1 
ATOM   9929  N NE    . ARG B 2 297  ? 206.172 390.553 208.466 1.00 162.08 ? 297  ARG C NE    1 
ATOM   9930  C CZ    . ARG B 2 297  ? 205.758 389.578 207.667 1.00 162.08 ? 297  ARG C CZ    1 
ATOM   9931  N NH1   . ARG B 2 297  ? 205.923 389.640 206.356 1.00 162.08 ? 297  ARG C NH1   1 
ATOM   9932  N NH2   . ARG B 2 297  ? 205.165 388.513 208.198 1.00 162.08 ? 297  ARG C NH2   1 
ATOM   9933  N N     . HIS B 2 298  ? 206.618 396.579 204.422 1.00 165.62 ? 298  HIS C N     1 
ATOM   9934  C CA    . HIS B 2 298  ? 206.694 398.003 204.130 1.00 165.62 ? 298  HIS C CA    1 
ATOM   9935  C C     . HIS B 2 298  ? 205.411 398.438 203.439 1.00 165.62 ? 298  HIS C C     1 
ATOM   9936  O O     . HIS B 2 298  ? 204.879 397.717 202.590 1.00 165.62 ? 298  HIS C O     1 
ATOM   9937  C CB    . HIS B 2 298  ? 207.904 398.331 203.247 1.00 165.62 ? 298  HIS C CB    1 
ATOM   9938  C CG    . HIS B 2 298  ? 207.930 397.579 201.953 1.00 165.62 ? 298  HIS C CG    1 
ATOM   9939  N ND1   . HIS B 2 298  ? 208.246 396.239 201.877 1.00 165.62 ? 298  HIS C ND1   1 
ATOM   9940  C CD2   . HIS B 2 298  ? 207.677 397.978 200.684 1.00 165.62 ? 298  HIS C CD2   1 
ATOM   9941  C CE1   . HIS B 2 298  ? 208.188 395.846 200.617 1.00 165.62 ? 298  HIS C CE1   1 
ATOM   9942  N NE2   . HIS B 2 298  ? 207.845 396.882 199.873 1.00 165.62 ? 298  HIS C NE2   1 
ATOM   9943  N N     . PHE B 2 299  ? 204.917 399.618 203.804 1.00 156.70 ? 299  PHE C N     1 
ATOM   9944  C CA    . PHE B 2 299  ? 203.670 400.126 203.250 1.00 156.70 ? 299  PHE C CA    1 
ATOM   9945  C C     . PHE B 2 299  ? 203.656 401.645 203.384 1.00 156.70 ? 299  PHE C C     1 
ATOM   9946  O O     . PHE B 2 299  ? 204.659 402.266 203.750 1.00 156.70 ? 299  PHE C O     1 
ATOM   9947  C CB    . PHE B 2 299  ? 202.465 399.475 203.943 1.00 156.70 ? 299  PHE C CB    1 
ATOM   9948  C CG    . PHE B 2 299  ? 202.712 399.112 205.381 1.00 156.70 ? 299  PHE C CG    1 
ATOM   9949  C CD1   . PHE B 2 299  ? 203.007 400.090 206.318 1.00 156.70 ? 299  PHE C CD1   1 
ATOM   9950  C CD2   . PHE B 2 299  ? 202.649 397.792 205.796 1.00 156.70 ? 299  PHE C CD2   1 
ATOM   9951  C CE1   . PHE B 2 299  ? 203.235 399.757 207.640 1.00 156.70 ? 299  PHE C CE1   1 
ATOM   9952  C CE2   . PHE B 2 299  ? 202.876 397.453 207.117 1.00 156.70 ? 299  PHE C CE2   1 
ATOM   9953  C CZ    . PHE B 2 299  ? 203.169 398.437 208.040 1.00 156.70 ? 299  PHE C CZ    1 
ATOM   9954  N N     . SER B 2 300  ? 202.505 402.241 203.083 1.00 152.93 ? 300  SER C N     1 
ATOM   9955  C CA    . SER B 2 300  ? 202.289 403.680 203.162 1.00 152.93 ? 300  SER C CA    1 
ATOM   9956  C C     . SER B 2 300  ? 202.141 404.102 204.619 1.00 152.93 ? 300  SER C C     1 
ATOM   9957  O O     . SER B 2 300  ? 201.943 403.246 205.491 1.00 152.93 ? 300  SER C O     1 
ATOM   9958  C CB    . SER B 2 300  ? 201.050 404.072 202.353 1.00 152.93 ? 300  SER C CB    1 
ATOM   9959  O OG    . SER B 2 300  ? 199.894 403.408 202.834 1.00 152.93 ? 300  SER C OG    1 
ATOM   9960  N N     . PRO B 2 301  ? 202.246 405.399 204.930 1.00 150.45 ? 301  PRO C N     1 
ATOM   9961  C CA    . PRO B 2 301  ? 202.023 405.832 206.320 1.00 150.45 ? 301  PRO C CA    1 
ATOM   9962  C C     . PRO B 2 301  ? 200.647 405.471 206.854 1.00 150.45 ? 301  PRO C C     1 
ATOM   9963  O O     . PRO B 2 301  ? 200.468 405.398 208.076 1.00 150.45 ? 301  PRO C O     1 
ATOM   9964  C CB    . PRO B 2 301  ? 202.219 407.352 206.247 1.00 150.45 ? 301  PRO C CB    1 
ATOM   9965  C CG    . PRO B 2 301  ? 203.136 407.552 205.093 1.00 150.45 ? 301  PRO C CG    1 
ATOM   9966  C CD    . PRO B 2 301  ? 202.777 406.490 204.092 1.00 150.45 ? 301  PRO C CD    1 
ATOM   9967  N N     . ARG B 2 302  ? 199.666 405.249 205.975 1.00 152.09 ? 302  ARG C N     1 
ATOM   9968  C CA    . ARG B 2 302  ? 198.370 404.750 206.425 1.00 152.09 ? 302  ARG C CA    1 
ATOM   9969  C C     . ARG B 2 302  ? 198.512 403.389 207.095 1.00 152.09 ? 302  ARG C C     1 
ATOM   9970  O O     . ARG B 2 302  ? 197.872 403.122 208.119 1.00 152.09 ? 302  ARG C O     1 
ATOM   9971  C CB    . ARG B 2 302  ? 197.400 404.667 205.246 1.00 152.09 ? 302  ARG C CB    1 
ATOM   9972  C CG    . ARG B 2 302  ? 196.835 406.004 204.800 1.00 152.09 ? 302  ARG C CG    1 
ATOM   9973  C CD    . ARG B 2 302  ? 195.841 405.820 203.665 1.00 152.09 ? 302  ARG C CD    1 
ATOM   9974  N NE    . ARG B 2 302  ? 195.040 407.016 203.434 1.00 152.09 ? 302  ARG C NE    1 
ATOM   9975  C CZ    . ARG B 2 302  ? 194.056 407.098 202.549 1.00 152.09 ? 302  ARG C CZ    1 
ATOM   9976  N NH1   . ARG B 2 302  ? 193.721 406.068 201.789 1.00 152.09 ? 302  ARG C NH1   1 
ATOM   9977  N NH2   . ARG B 2 302  ? 193.391 408.243 202.422 1.00 152.09 ? 302  ARG C NH2   1 
ATOM   9978  N N     . GLY B 2 303  ? 199.345 402.514 206.527 1.00 150.72 ? 303  GLY C N     1 
ATOM   9979  C CA    . GLY B 2 303  ? 199.592 401.228 207.157 1.00 150.72 ? 303  GLY C CA    1 
ATOM   9980  C C     . GLY B 2 303  ? 200.252 401.360 208.515 1.00 150.72 ? 303  GLY C C     1 
ATOM   9981  O O     . GLY B 2 303  ? 199.912 400.637 209.454 1.00 150.72 ? 303  GLY C O     1 
ATOM   9982  N N     . LYS B 2 304  ? 201.209 402.284 208.638 1.00 149.33 ? 304  LYS C N     1 
ATOM   9983  C CA    . LYS B 2 304  ? 201.847 402.521 209.929 1.00 149.33 ? 304  LYS C CA    1 
ATOM   9984  C C     . LYS B 2 304  ? 200.843 403.037 210.953 1.00 149.33 ? 304  LYS C C     1 
ATOM   9985  O O     . LYS B 2 304  ? 200.863 402.623 212.118 1.00 149.33 ? 304  LYS C O     1 
ATOM   9986  C CB    . LYS B 2 304  ? 203.006 403.504 209.771 1.00 149.33 ? 304  LYS C CB    1 
ATOM   9987  C CG    . LYS B 2 304  ? 204.238 402.914 209.104 1.00 149.33 ? 304  LYS C CG    1 
ATOM   9988  C CD    . LYS B 2 304  ? 205.322 403.963 208.922 1.00 149.33 ? 304  LYS C CD    1 
ATOM   9989  C CE    . LYS B 2 304  ? 206.514 403.401 208.165 1.00 149.33 ? 304  LYS C CE    1 
ATOM   9990  N NZ    . LYS B 2 304  ? 207.617 404.396 208.048 1.00 149.33 ? 304  LYS C NZ    1 
ATOM   9991  N N     . PHE B 2 305  ? 199.958 403.947 210.536 1.00 146.87 ? 305  PHE C N     1 
ATOM   9992  C CA    . PHE B 2 305  ? 198.932 404.451 211.443 1.00 146.87 ? 305  PHE C CA    1 
ATOM   9993  C C     . PHE B 2 305  ? 197.982 403.340 211.874 1.00 146.87 ? 305  PHE C C     1 
ATOM   9994  O O     . PHE B 2 305  ? 197.596 403.263 213.046 1.00 146.87 ? 305  PHE C O     1 
ATOM   9995  C CB    . PHE B 2 305  ? 198.159 405.592 210.780 1.00 146.87 ? 305  PHE C CB    1 
ATOM   9996  C CG    . PHE B 2 305  ? 197.796 406.705 211.721 1.00 146.87 ? 305  PHE C CG    1 
ATOM   9997  C CD1   . PHE B 2 305  ? 196.787 406.538 212.655 1.00 146.87 ? 305  PHE C CD1   1 
ATOM   9998  C CD2   . PHE B 2 305  ? 198.463 407.918 211.672 1.00 146.87 ? 305  PHE C CD2   1 
ATOM   9999  C CE1   . PHE B 2 305  ? 196.450 407.559 213.523 1.00 146.87 ? 305  PHE C CE1   1 
ATOM   10000 C CE2   . PHE B 2 305  ? 198.130 408.943 212.537 1.00 146.87 ? 305  PHE C CE2   1 
ATOM   10001 C CZ    . PHE B 2 305  ? 197.122 408.764 213.463 1.00 146.87 ? 305  PHE C CZ    1 
ATOM   10002 N N     . LYS B 2 306  ? 197.592 402.472 210.937 1.00 145.26 ? 306  LYS C N     1 
ATOM   10003 C CA    . LYS B 2 306  ? 196.727 401.348 211.282 1.00 145.26 ? 306  LYS C CA    1 
ATOM   10004 C C     . LYS B 2 306  ? 197.418 400.399 212.254 1.00 145.26 ? 306  LYS C C     1 
ATOM   10005 O O     . LYS B 2 306  ? 196.793 399.901 213.199 1.00 145.26 ? 306  LYS C O     1 
ATOM   10006 C CB    . LYS B 2 306  ? 196.303 400.605 210.015 1.00 145.26 ? 306  LYS C CB    1 
ATOM   10007 C CG    . LYS B 2 306  ? 195.230 399.551 210.242 1.00 145.26 ? 306  LYS C CG    1 
ATOM   10008 C CD    . LYS B 2 306  ? 193.883 400.009 209.708 1.00 145.26 ? 306  LYS C CD    1 
ATOM   10009 C CE    . LYS B 2 306  ? 192.827 398.930 209.877 1.00 145.26 ? 306  LYS C CE    1 
ATOM   10010 N NZ    . LYS B 2 306  ? 193.041 397.792 208.941 1.00 145.26 ? 306  LYS C NZ    1 
ATOM   10011 N N     . VAL B 2 307  ? 198.708 400.135 212.036 1.00 140.92 ? 307  VAL C N     1 
ATOM   10012 C CA    . VAL B 2 307  ? 199.459 399.265 212.938 1.00 140.92 ? 307  VAL C CA    1 
ATOM   10013 C C     . VAL B 2 307  ? 199.541 399.882 214.328 1.00 140.92 ? 307  VAL C C     1 
ATOM   10014 O O     . VAL B 2 307  ? 199.391 399.188 215.340 1.00 140.92 ? 307  VAL C O     1 
ATOM   10015 C CB    . VAL B 2 307  ? 200.858 398.977 212.362 1.00 140.92 ? 307  VAL C CB    1 
ATOM   10016 N N     . ILE B 2 308  ? 199.788 401.192 214.399 1.00 141.51 ? 308  ILE C N     1 
ATOM   10017 C CA    . ILE B 2 308  ? 199.858 401.872 215.690 1.00 141.51 ? 308  ILE C CA    1 
ATOM   10018 C C     . ILE B 2 308  ? 198.511 401.807 216.402 1.00 141.51 ? 308  ILE C C     1 
ATOM   10019 O O     . ILE B 2 308  ? 198.443 401.558 217.613 1.00 141.51 ? 308  ILE C O     1 
ATOM   10020 C CB    . ILE B 2 308  ? 200.336 403.325 215.500 1.00 141.51 ? 308  ILE C CB    1 
ATOM   10021 C CG1   . ILE B 2 308  ? 201.865 403.383 215.485 1.00 141.51 ? 308  ILE C CG1   1 
ATOM   10022 C CG2   . ILE B 2 308  ? 199.781 404.230 216.592 1.00 141.51 ? 308  ILE C CG2   1 
ATOM   10023 C CD1   . ILE B 2 308  ? 202.420 404.747 215.136 1.00 141.51 ? 308  ILE C CD1   1 
ATOM   10024 N N     . ALA B 2 309  ? 197.420 402.028 215.664 1.00 142.38 ? 309  ALA C N     1 
ATOM   10025 C CA    . ALA B 2 309  ? 196.091 401.959 216.264 1.00 142.38 ? 309  ALA C CA    1 
ATOM   10026 C C     . ALA B 2 309  ? 195.788 400.558 216.780 1.00 142.38 ? 309  ALA C C     1 
ATOM   10027 O O     . ALA B 2 309  ? 195.231 400.398 217.873 1.00 142.38 ? 309  ALA C O     1 
ATOM   10028 C CB    . ALA B 2 309  ? 195.034 402.401 215.252 1.00 142.38 ? 309  ALA C CB    1 
ATOM   10029 N N     . LEU B 2 310  ? 196.144 399.529 216.006 1.00 144.54 ? 310  LEU C N     1 
ATOM   10030 C CA    . LEU B 2 310  ? 195.919 398.157 216.452 1.00 144.54 ? 310  LEU C CA    1 
ATOM   10031 C C     . LEU B 2 310  ? 196.762 397.831 217.680 1.00 144.54 ? 310  LEU C C     1 
ATOM   10032 O O     . LEU B 2 310  ? 196.299 397.134 218.591 1.00 144.54 ? 310  LEU C O     1 
ATOM   10033 C CB    . LEU B 2 310  ? 196.214 397.180 215.315 1.00 144.54 ? 310  LEU C CB    1 
ATOM   10034 C CG    . LEU B 2 310  ? 195.133 397.091 214.234 1.00 144.54 ? 310  LEU C CG    1 
ATOM   10035 C CD1   . LEU B 2 310  ? 195.618 396.284 213.041 1.00 144.54 ? 310  LEU C CD1   1 
ATOM   10036 C CD2   . LEU B 2 310  ? 193.854 396.496 214.803 1.00 144.54 ? 310  LEU C CD2   1 
ATOM   10037 N N     . THR B 2 311  ? 198.003 398.323 217.720 1.00 142.37 ? 311  THR C N     1 
ATOM   10038 C CA    . THR B 2 311  ? 198.844 398.122 218.896 1.00 142.37 ? 311  THR C CA    1 
ATOM   10039 C C     . THR B 2 311  ? 198.238 398.788 220.125 1.00 142.37 ? 311  THR C C     1 
ATOM   10040 O O     . THR B 2 311  ? 198.232 398.206 221.217 1.00 142.37 ? 311  THR C O     1 
ATOM   10041 C CB    . THR B 2 311  ? 200.250 398.664 218.633 1.00 142.37 ? 311  THR C CB    1 
ATOM   10042 O OG1   . THR B 2 311  ? 200.820 397.994 217.502 1.00 142.37 ? 311  THR C OG1   1 
ATOM   10043 C CG2   . THR B 2 311  ? 201.144 398.454 219.848 1.00 142.37 ? 311  THR C CG2   1 
ATOM   10044 N N     . VAL B 2 312  ? 197.721 400.008 219.965 1.00 141.08 ? 312  VAL C N     1 
ATOM   10045 C CA    . VAL B 2 312  ? 197.084 400.702 221.081 1.00 141.08 ? 312  VAL C CA    1 
ATOM   10046 C C     . VAL B 2 312  ? 195.853 399.938 221.551 1.00 141.08 ? 312  VAL C C     1 
ATOM   10047 O O     . VAL B 2 312  ? 195.617 399.791 222.758 1.00 141.08 ? 312  VAL C O     1 
ATOM   10048 C CB    . VAL B 2 312  ? 196.738 402.150 220.684 1.00 141.08 ? 312  VAL C CB    1 
ATOM   10049 C CG1   . VAL B 2 312  ? 195.857 402.799 221.740 1.00 141.08 ? 312  VAL C CG1   1 
ATOM   10050 C CG2   . VAL B 2 312  ? 198.009 402.960 220.481 1.00 141.08 ? 312  VAL C CG2   1 
ATOM   10051 N N     . LEU B 2 313  ? 195.047 399.442 220.609 1.00 141.93 ? 313  LEU C N     1 
ATOM   10052 C CA    . LEU B 2 313  ? 193.860 398.676 220.978 1.00 141.93 ? 313  LEU C CA    1 
ATOM   10053 C C     . LEU B 2 313  ? 194.235 397.403 221.728 1.00 141.93 ? 313  LEU C C     1 
ATOM   10054 O O     . LEU B 2 313  ? 193.597 397.053 222.728 1.00 141.93 ? 313  LEU C O     1 
ATOM   10055 C CB    . LEU B 2 313  ? 193.039 398.342 219.733 1.00 141.93 ? 313  LEU C CB    1 
ATOM   10056 C CG    . LEU B 2 313  ? 192.241 399.490 219.111 1.00 141.93 ? 313  LEU C CG    1 
ATOM   10057 C CD1   . LEU B 2 313  ? 192.143 399.324 217.602 1.00 141.93 ? 313  LEU C CD1   1 
ATOM   10058 C CD2   . LEU B 2 313  ? 190.857 399.583 219.734 1.00 141.93 ? 313  LEU C CD2   1 
ATOM   10059 N N     . ALA B 2 314  ? 195.270 396.699 221.262 1.00 143.00 ? 314  ALA C N     1 
ATOM   10060 C CA    . ALA B 2 314  ? 195.719 395.493 221.952 1.00 143.00 ? 314  ALA C CA    1 
ATOM   10061 C C     . ALA B 2 314  ? 196.236 395.815 223.349 1.00 143.00 ? 314  ALA C C     1 
ATOM   10062 O O     . ALA B 2 314  ? 195.983 395.067 224.302 1.00 143.00 ? 314  ALA C O     1 
ATOM   10063 C CB    . ALA B 2 314  ? 196.797 394.788 221.129 1.00 143.00 ? 314  ALA C CB    1 
ATOM   10064 N N     . SER B 2 315  ? 196.970 396.922 223.489 1.00 143.68 ? 315  SER C N     1 
ATOM   10065 C CA    . SER B 2 315  ? 197.462 397.322 224.803 1.00 143.68 ? 315  SER C CA    1 
ATOM   10066 C C     . SER B 2 315  ? 196.311 397.632 225.751 1.00 143.68 ? 315  SER C C     1 
ATOM   10067 O O     . SER B 2 315  ? 196.331 397.226 226.918 1.00 143.68 ? 315  SER C O     1 
ATOM   10068 C CB    . SER B 2 315  ? 198.390 398.529 224.671 1.00 143.68 ? 315  SER C CB    1 
ATOM   10069 O OG    . SER B 2 315  ? 198.461 399.254 225.887 1.00 143.68 ? 315  SER C OG    1 
ATOM   10070 N N     . VAL B 2 316  ? 195.290 398.343 225.266 1.00 144.31 ? 316  VAL C N     1 
ATOM   10071 C CA    . VAL B 2 316  ? 194.140 398.653 226.112 1.00 144.31 ? 316  VAL C CA    1 
ATOM   10072 C C     . VAL B 2 316  ? 193.389 397.378 226.482 1.00 144.31 ? 316  VAL C C     1 
ATOM   10073 O O     . VAL B 2 316  ? 192.908 397.230 227.613 1.00 144.31 ? 316  VAL C O     1 
ATOM   10074 C CB    . VAL B 2 316  ? 193.221 399.679 225.422 1.00 144.31 ? 316  VAL C CB    1 
ATOM   10075 C CG1   . VAL B 2 316  ? 192.000 399.961 226.282 1.00 144.31 ? 316  VAL C CG1   1 
ATOM   10076 C CG2   . VAL B 2 316  ? 193.978 400.970 225.158 1.00 144.31 ? 316  VAL C CG2   1 
ATOM   10077 N N     . ARG B 2 317  ? 193.279 396.437 225.539 1.00 144.00 ? 317  ARG C N     1 
ATOM   10078 C CA    . ARG B 2 317  ? 192.629 395.164 225.838 1.00 144.00 ? 317  ARG C CA    1 
ATOM   10079 C C     . ARG B 2 317  ? 193.385 394.396 226.915 1.00 144.00 ? 317  ARG C C     1 
ATOM   10080 O O     . ARG B 2 317  ? 192.773 393.822 227.825 1.00 144.00 ? 317  ARG C O     1 
ATOM   10081 C CB    . ARG B 2 317  ? 192.510 394.320 224.568 1.00 144.00 ? 317  ARG C CB    1 
ATOM   10082 C CG    . ARG B 2 317  ? 191.448 394.798 223.591 1.00 144.00 ? 317  ARG C CG    1 
ATOM   10083 C CD    . ARG B 2 317  ? 191.519 394.035 222.278 1.00 144.00 ? 317  ARG C CD    1 
ATOM   10084 N NE    . ARG B 2 317  ? 190.599 394.576 221.284 1.00 144.00 ? 317  ARG C NE    1 
ATOM   10085 C CZ    . ARG B 2 317  ? 190.286 393.971 220.146 1.00 144.00 ? 317  ARG C CZ    1 
ATOM   10086 N NH1   . ARG B 2 317  ? 190.802 392.797 219.822 1.00 144.00 ? 317  ARG C NH1   1 
ATOM   10087 N NH2   . ARG B 2 317  ? 189.433 394.560 219.313 1.00 144.00 ? 317  ARG C NH2   1 
ATOM   10088 N N     . ILE B 2 318  ? 194.717 394.372 226.830 1.00 146.00 ? 318  ILE C N     1 
ATOM   10089 C CA    . ILE B 2 318  ? 195.504 393.663 227.834 1.00 146.00 ? 318  ILE C CA    1 
ATOM   10090 C C     . ILE B 2 318  ? 195.505 394.421 229.157 1.00 146.00 ? 318  ILE C C     1 
ATOM   10091 O O     . ILE B 2 318  ? 195.757 393.835 230.217 1.00 146.00 ? 318  ILE C O     1 
ATOM   10092 C CB    . ILE B 2 318  ? 196.934 393.412 227.315 1.00 146.00 ? 318  ILE C CB    1 
ATOM   10093 C CG1   . ILE B 2 318  ? 197.403 392.008 227.704 1.00 146.00 ? 318  ILE C CG1   1 
ATOM   10094 C CG2   . ILE B 2 318  ? 197.902 394.466 227.836 1.00 146.00 ? 318  ILE C CG2   1 
ATOM   10095 C CD1   . ILE B 2 318  ? 196.631 390.896 227.029 1.00 146.00 ? 318  ILE C CD1   1 
ATOM   10096 N N     . TYR B 2 319  ? 195.222 395.723 229.124 1.00 149.26 ? 319  TYR C N     1 
ATOM   10097 C CA    . TYR B 2 319  ? 195.153 396.531 230.335 1.00 149.26 ? 319  TYR C CA    1 
ATOM   10098 C C     . TYR B 2 319  ? 193.919 396.196 231.164 1.00 149.26 ? 319  TYR C C     1 
ATOM   10099 O O     . TYR B 2 319  ? 193.846 396.547 232.346 1.00 149.26 ? 319  TYR C O     1 
ATOM   10100 C CB    . TYR B 2 319  ? 195.158 398.020 229.975 1.00 149.26 ? 319  TYR C CB    1 
ATOM   10101 C CG    . TYR B 2 319  ? 195.467 398.940 231.134 1.00 149.26 ? 319  TYR C CG    1 
ATOM   10102 C CD1   . TYR B 2 319  ? 196.776 399.177 231.531 1.00 149.26 ? 319  TYR C CD1   1 
ATOM   10103 C CD2   . TYR B 2 319  ? 194.446 399.577 231.828 1.00 149.26 ? 319  TYR C CD2   1 
ATOM   10104 C CE1   . TYR B 2 319  ? 197.060 400.020 232.591 1.00 149.26 ? 319  TYR C CE1   1 
ATOM   10105 C CE2   . TYR B 2 319  ? 194.719 400.419 232.888 1.00 149.26 ? 319  TYR C CE2   1 
ATOM   10106 C CZ    . TYR B 2 319  ? 196.027 400.637 233.265 1.00 149.26 ? 319  TYR C CZ    1 
ATOM   10107 O OH    . TYR B 2 319  ? 196.299 401.477 234.320 1.00 149.26 ? 319  TYR C OH    1 
ATOM   10108 N N     . TYR B 2 320  ? 192.943 395.521 230.558 1.00 148.49 ? 320  TYR C N     1 
ATOM   10109 C CA    . TYR B 2 320  ? 191.696 395.197 231.235 1.00 148.49 ? 320  TYR C CA    1 
ATOM   10110 C C     . TYR B 2 320  ? 191.586 393.750 231.691 1.00 148.49 ? 320  TYR C C     1 
ATOM   10111 O O     . TYR B 2 320  ? 190.548 393.380 232.249 1.00 148.49 ? 320  TYR C O     1 
ATOM   10112 C CB    . TYR B 2 320  ? 190.496 395.519 230.331 1.00 148.49 ? 320  TYR C CB    1 
ATOM   10113 C CG    . TYR B 2 320  ? 189.958 396.921 230.499 1.00 148.49 ? 320  TYR C CG    1 
ATOM   10114 C CD1   . TYR B 2 320  ? 190.729 397.917 231.083 1.00 148.49 ? 320  TYR C CD1   1 
ATOM   10115 C CD2   . TYR B 2 320  ? 188.674 397.246 230.081 1.00 148.49 ? 320  TYR C CD2   1 
ATOM   10116 C CE1   . TYR B 2 320  ? 190.239 399.199 231.242 1.00 148.49 ? 320  TYR C CE1   1 
ATOM   10117 C CE2   . TYR B 2 320  ? 188.175 398.524 230.236 1.00 148.49 ? 320  TYR C CE2   1 
ATOM   10118 C CZ    . TYR B 2 320  ? 188.961 399.496 230.816 1.00 148.49 ? 320  TYR C CZ    1 
ATOM   10119 O OH    . TYR B 2 320  ? 188.467 400.770 230.972 1.00 148.49 ? 320  TYR C OH    1 
ATOM   10120 N N     . GLN B 2 321  ? 192.610 392.923 231.475 1.00 149.63 ? 321  GLN C N     1 
ATOM   10121 C CA    . GLN B 2 321  ? 192.492 391.508 231.815 1.00 149.63 ? 321  GLN C CA    1 
ATOM   10122 C C     . GLN B 2 321  ? 192.472 391.297 233.325 1.00 149.63 ? 321  GLN C C     1 
ATOM   10123 O O     . GLN B 2 321  ? 191.622 390.566 233.848 1.00 149.63 ? 321  GLN C O     1 
ATOM   10124 C CB    . GLN B 2 321  ? 193.630 390.715 231.171 1.00 149.63 ? 321  GLN C CB    1 
ATOM   10125 C CG    . GLN B 2 321  ? 193.440 390.470 229.682 1.00 149.63 ? 321  GLN C CG    1 
ATOM   10126 C CD    . GLN B 2 321  ? 192.916 389.079 229.382 1.00 149.63 ? 321  GLN C CD    1 
ATOM   10127 O OE1   . GLN B 2 321  ? 193.462 388.082 229.851 1.00 149.63 ? 321  GLN C OE1   1 
ATOM   10128 N NE2   . GLN B 2 321  ? 191.849 389.008 228.594 1.00 149.63 ? 321  GLN C NE2   1 
ATOM   10129 N N     . TYR B 2 322  ? 193.396 391.937 234.046 1.00 150.63 ? 322  TYR C N     1 
ATOM   10130 C CA    . TYR B 2 322  ? 193.513 391.678 235.479 1.00 150.63 ? 322  TYR C CA    1 
ATOM   10131 C C     . TYR B 2 322  ? 192.314 392.221 236.248 1.00 150.63 ? 322  TYR C C     1 
ATOM   10132 O O     . TYR B 2 322  ? 191.910 391.643 237.263 1.00 150.63 ? 322  TYR C O     1 
ATOM   10133 C CB    . TYR B 2 322  ? 194.814 392.266 236.027 1.00 150.63 ? 322  TYR C CB    1 
ATOM   10134 C CG    . TYR B 2 322  ? 195.163 393.641 235.508 1.00 150.63 ? 322  TYR C CG    1 
ATOM   10135 C CD1   . TYR B 2 322  ? 194.638 394.781 236.101 1.00 150.63 ? 322  TYR C CD1   1 
ATOM   10136 C CD2   . TYR B 2 322  ? 196.032 393.801 234.436 1.00 150.63 ? 322  TYR C CD2   1 
ATOM   10137 C CE1   . TYR B 2 322  ? 194.958 396.041 235.635 1.00 150.63 ? 322  TYR C CE1   1 
ATOM   10138 C CE2   . TYR B 2 322  ? 196.358 395.056 233.963 1.00 150.63 ? 322  TYR C CE2   1 
ATOM   10139 C CZ    . TYR B 2 322  ? 195.820 396.172 234.568 1.00 150.63 ? 322  TYR C CZ    1 
ATOM   10140 O OH    . TYR B 2 322  ? 196.141 397.425 234.101 1.00 150.63 ? 322  TYR C OH    1 
ATOM   10141 N N     . ARG B 2 323  ? 191.735 393.333 235.790 1.00 153.70 ? 323  ARG C N     1 
ATOM   10142 C CA    . ARG B 2 323  ? 190.584 393.895 236.484 1.00 153.70 ? 323  ARG C CA    1 
ATOM   10143 C C     . ARG B 2 323  ? 189.297 393.137 236.182 1.00 153.70 ? 323  ARG C C     1 
ATOM   10144 O O     . ARG B 2 323  ? 188.297 393.340 236.878 1.00 153.70 ? 323  ARG C O     1 
ATOM   10145 C CB    . ARG B 2 323  ? 190.417 395.372 236.125 1.00 153.70 ? 323  ARG C CB    1 
ATOM   10146 C CG    . ARG B 2 323  ? 190.268 395.642 234.639 1.00 153.70 ? 323  ARG C CG    1 
ATOM   10147 C CD    . ARG B 2 323  ? 189.793 397.064 234.390 1.00 153.70 ? 323  ARG C CD    1 
ATOM   10148 N NE    . ARG B 2 323  ? 188.661 397.418 235.238 1.00 153.70 ? 323  ARG C NE    1 
ATOM   10149 C CZ    . ARG B 2 323  ? 187.688 398.245 234.882 1.00 153.70 ? 323  ARG C CZ    1 
ATOM   10150 N NH1   . ARG B 2 323  ? 187.674 398.826 233.693 1.00 153.70 ? 323  ARG C NH1   1 
ATOM   10151 N NH2   . ARG B 2 323  ? 186.703 398.497 235.740 1.00 153.70 ? 323  ARG C NH2   1 
ATOM   10152 N N     . ARG B 2 324  ? 189.298 392.274 235.169 1.00 152.45 ? 324  ARG C N     1 
ATOM   10153 C CA    . ARG B 2 324  ? 188.123 391.489 234.813 1.00 152.45 ? 324  ARG C CA    1 
ATOM   10154 C C     . ARG B 2 324  ? 188.099 390.115 235.470 1.00 152.45 ? 324  ARG C C     1 
ATOM   10155 O O     . ARG B 2 324  ? 187.143 389.362 235.257 1.00 152.45 ? 324  ARG C O     1 
ATOM   10156 C CB    . ARG B 2 324  ? 188.035 391.326 233.292 1.00 152.45 ? 324  ARG C CB    1 
ATOM   10157 C CG    . ARG B 2 324  ? 187.511 392.550 232.558 1.00 152.45 ? 324  ARG C CG    1 
ATOM   10158 C CD    . ARG B 2 324  ? 186.149 392.979 233.082 1.00 152.45 ? 324  ARG C CD    1 
ATOM   10159 N NE    . ARG B 2 324  ? 185.550 394.027 232.264 1.00 152.45 ? 324  ARG C NE    1 
ATOM   10160 C CZ    . ARG B 2 324  ? 185.972 395.285 232.221 1.00 152.45 ? 324  ARG C CZ    1 
ATOM   10161 N NH1   . ARG B 2 324  ? 186.990 395.699 232.958 1.00 152.45 ? 324  ARG C NH1   1 
ATOM   10162 N NH2   . ARG B 2 324  ? 185.352 396.149 231.423 1.00 152.45 ? 324  ARG C NH2   1 
ATOM   10163 N N     . VAL B 2 325  ? 189.119 389.767 236.255 1.00 146.92 ? 325  VAL C N     1 
ATOM   10164 C CA    . VAL B 2 325  ? 189.157 388.454 236.889 1.00 146.92 ? 325  VAL C CA    1 
ATOM   10165 C C     . VAL B 2 325  ? 188.107 388.397 237.991 1.00 146.92 ? 325  VAL C C     1 
ATOM   10166 O O     . VAL B 2 325  ? 187.819 389.403 238.654 1.00 146.92 ? 325  VAL C O     1 
ATOM   10167 C CB    . VAL B 2 325  ? 190.564 388.150 237.428 1.00 146.92 ? 325  VAL C CB    1 
ATOM   10168 C CG1   . VAL B 2 325  ? 190.874 388.989 238.662 1.00 146.92 ? 325  VAL C CG1   1 
ATOM   10169 C CG2   . VAL B 2 325  ? 190.713 386.665 237.730 1.00 146.92 ? 325  VAL C CG2   1 
ATOM   10170 N N     . LYS B 2 326  ? 187.506 387.227 238.169 1.00 135.64 ? 326  LYS C N     1 
ATOM   10171 C CA    . LYS B 2 326  ? 186.495 387.049 239.194 1.00 135.64 ? 326  LYS C CA    1 
ATOM   10172 C C     . LYS B 2 326  ? 187.128 386.586 240.502 1.00 135.64 ? 326  LYS C C     1 
ATOM   10173 O O     . LYS B 2 326  ? 188.127 385.862 240.502 1.00 135.64 ? 326  LYS C O     1 
ATOM   10174 C CB    . LYS B 2 326  ? 185.449 386.040 238.730 1.00 135.64 ? 326  LYS C CB    1 
ATOM   10175 C CG    . LYS B 2 326  ? 184.597 386.513 237.559 1.00 135.64 ? 326  LYS C CG    1 
ATOM   10176 C CD    . LYS B 2 326  ? 184.089 387.934 237.763 1.00 135.64 ? 326  LYS C CD    1 
ATOM   10177 C CE    . LYS B 2 326  ? 183.023 387.997 238.847 1.00 135.64 ? 326  LYS C CE    1 
ATOM   10178 N NZ    . LYS B 2 326  ? 182.620 389.399 239.146 1.00 135.64 ? 326  LYS C NZ    1 
ATOM   10179 N N     . PRO B 2 327  ? 186.560 386.993 241.640 1.00 129.98 ? 327  PRO C N     1 
ATOM   10180 C CA    . PRO B 2 327  ? 187.067 386.510 242.932 1.00 129.98 ? 327  PRO C CA    1 
ATOM   10181 C C     . PRO B 2 327  ? 186.588 385.099 243.235 1.00 129.98 ? 327  PRO C C     1 
ATOM   10182 O O     . PRO B 2 327  ? 186.020 384.435 242.361 1.00 129.98 ? 327  PRO C O     1 
ATOM   10183 C CB    . PRO B 2 327  ? 186.518 387.531 243.934 1.00 129.98 ? 327  PRO C CB    1 
ATOM   10184 C CG    . PRO B 2 327  ? 185.314 388.112 243.282 1.00 129.98 ? 327  PRO C CG    1 
ATOM   10185 C CD    . PRO B 2 327  ? 185.441 387.939 241.791 1.00 129.98 ? 327  PRO C CD    1 
ATOM   10186 N N     . VAL B 2 328  ? 186.835 384.625 244.460 1.00 122.68 ? 328  VAL C N     1 
ATOM   10187 C CA    . VAL B 2 328  ? 186.489 383.250 244.818 1.00 122.68 ? 328  VAL C CA    1 
ATOM   10188 C C     . VAL B 2 328  ? 185.003 382.995 244.590 1.00 122.68 ? 328  VAL C C     1 
ATOM   10189 O O     . VAL B 2 328  ? 184.618 382.009 243.950 1.00 122.68 ? 328  VAL C O     1 
ATOM   10190 C CB    . VAL B 2 328  ? 186.896 382.955 246.273 1.00 122.68 ? 328  VAL C CB    1 
ATOM   10191 C CG1   . VAL B 2 328  ? 186.192 381.705 246.779 1.00 122.68 ? 328  VAL C CG1   1 
ATOM   10192 C CG2   . VAL B 2 328  ? 188.406 382.806 246.380 1.00 122.68 ? 328  VAL C CG2   1 
ATOM   10193 N N     . THR B 2 329  ? 184.151 383.891 245.091 1.00 123.28 ? 329  THR C N     1 
ATOM   10194 C CA    . THR B 2 329  ? 182.706 383.860 244.850 1.00 123.28 ? 329  THR C CA    1 
ATOM   10195 C C     . THR B 2 329  ? 182.106 382.493 245.188 1.00 123.28 ? 329  THR C C     1 
ATOM   10196 O O     . THR B 2 329  ? 181.682 381.732 244.317 1.00 123.28 ? 329  THR C O     1 
ATOM   10197 C CB    . THR B 2 329  ? 182.372 384.262 243.409 1.00 123.28 ? 329  THR C CB    1 
ATOM   10198 O OG1   . THR B 2 329  ? 183.123 383.461 242.489 1.00 123.28 ? 329  THR C OG1   1 
ATOM   10199 C CG2   . THR B 2 329  ? 182.684 385.729 243.177 1.00 123.28 ? 329  THR C CG2   1 
ATOM   10200 N N     . ARG B 2 330  ? 182.088 382.187 246.488 1.00 118.11 ? 330  ARG C N     1 
ATOM   10201 C CA    . ARG B 2 330  ? 181.523 380.919 246.940 1.00 118.11 ? 330  ARG C CA    1 
ATOM   10202 C C     . ARG B 2 330  ? 180.029 380.824 246.649 1.00 118.11 ? 330  ARG C C     1 
ATOM   10203 O O     . ARG B 2 330  ? 179.459 379.728 246.695 1.00 118.11 ? 330  ARG C O     1 
ATOM   10204 C CB    . ARG B 2 330  ? 181.785 380.732 248.435 1.00 118.11 ? 330  ARG C CB    1 
ATOM   10205 N N     . GLU B 2 331  ? 179.377 381.953 246.354 1.00 120.45 ? 331  GLU C N     1 
ATOM   10206 C CA    . GLU B 2 331  ? 177.945 381.928 246.067 1.00 120.45 ? 331  GLU C CA    1 
ATOM   10207 C C     . GLU B 2 331  ? 177.645 381.157 244.785 1.00 120.45 ? 331  GLU C C     1 
ATOM   10208 O O     . GLU B 2 331  ? 176.775 380.276 244.768 1.00 120.45 ? 331  GLU C O     1 
ATOM   10209 C CB    . GLU B 2 331  ? 177.405 383.355 245.973 1.00 120.45 ? 331  GLU C CB    1 
ATOM   10210 N N     . ILE B 2 332  ? 178.352 381.468 243.698 1.00 120.22 ? 332  ILE C N     1 
ATOM   10211 C CA    . ILE B 2 332  ? 178.131 380.707 242.474 1.00 120.22 ? 332  ILE C CA    1 
ATOM   10212 C C     . ILE B 2 332  ? 178.631 379.280 242.646 1.00 120.22 ? 332  ILE C C     1 
ATOM   10213 O O     . ILE B 2 332  ? 178.089 378.345 242.048 1.00 120.22 ? 332  ILE C O     1 
ATOM   10214 C CB    . ILE B 2 332  ? 178.773 381.399 241.257 1.00 120.22 ? 332  ILE C CB    1 
ATOM   10215 C CG1   . ILE B 2 332  ? 180.287 381.535 241.421 1.00 120.22 ? 332  ILE C CG1   1 
ATOM   10216 C CG2   . ILE B 2 332  ? 178.125 382.759 241.020 1.00 120.22 ? 332  ILE C CG2   1 
ATOM   10217 C CD1   . ILE B 2 332  ? 180.900 382.562 240.492 1.00 120.22 ? 332  ILE C CD1   1 
ATOM   10218 N N     . VAL B 2 333  ? 179.653 379.085 243.484 1.00 116.35 ? 333  VAL C N     1 
ATOM   10219 C CA    . VAL B 2 333  ? 180.173 377.742 243.732 1.00 116.35 ? 333  VAL C CA    1 
ATOM   10220 C C     . VAL B 2 333  ? 179.097 376.861 244.356 1.00 116.35 ? 333  VAL C C     1 
ATOM   10221 O O     . VAL B 2 333  ? 178.878 375.721 243.929 1.00 116.35 ? 333  VAL C O     1 
ATOM   10222 C CB    . VAL B 2 333  ? 181.433 377.811 244.615 1.00 116.35 ? 333  VAL C CB    1 
ATOM   10223 C CG1   . VAL B 2 333  ? 181.662 376.487 245.332 1.00 116.35 ? 333  VAL C CG1   1 
ATOM   10224 C CG2   . VAL B 2 333  ? 182.646 378.188 243.779 1.00 116.35 ? 333  VAL C CG2   1 
ATOM   10225 N N     . ILE B 2 334  ? 178.403 377.377 245.374 1.00 114.46 ? 334  ILE C N     1 
ATOM   10226 C CA    . ILE B 2 334  ? 177.332 376.602 245.993 1.00 114.46 ? 334  ILE C CA    1 
ATOM   10227 C C     . ILE B 2 334  ? 176.145 376.466 245.045 1.00 114.46 ? 334  ILE C C     1 
ATOM   10228 O O     . ILE B 2 334  ? 175.491 375.417 245.003 1.00 114.46 ? 334  ILE C O     1 
ATOM   10229 C CB    . ILE B 2 334  ? 176.926 377.202 247.356 1.00 114.46 ? 334  ILE C CB    1 
ATOM   10230 C CG1   . ILE B 2 334  ? 175.927 376.287 248.068 1.00 114.46 ? 334  ILE C CG1   1 
ATOM   10231 C CG2   . ILE B 2 334  ? 176.340 378.590 247.215 1.00 114.46 ? 334  ILE C CG2   1 
ATOM   10232 C CD1   . ILE B 2 334  ? 176.536 375.043 248.645 1.00 114.46 ? 334  ILE C CD1   1 
ATOM   10233 N N     . ARG B 2 335  ? 175.842 377.510 244.264 1.00 118.36 ? 335  ARG C N     1 
ATOM   10234 C CA    . ARG B 2 335  ? 174.702 377.399 243.358 1.00 118.36 ? 335  ARG C CA    1 
ATOM   10235 C C     . ARG B 2 335  ? 175.051 376.585 242.113 1.00 118.36 ? 335  ARG C C     1 
ATOM   10236 O O     . ARG B 2 335  ? 174.197 375.866 241.581 1.00 118.36 ? 335  ARG C O     1 
ATOM   10237 C CB    . ARG B 2 335  ? 174.172 378.786 242.982 1.00 118.36 ? 335  ARG C CB    1 
ATOM   10238 C CG    . ARG B 2 335  ? 174.919 379.498 241.871 1.00 118.36 ? 335  ARG C CG    1 
ATOM   10239 C CD    . ARG B 2 335  ? 174.540 380.972 241.792 1.00 118.36 ? 335  ARG C CD    1 
ATOM   10240 N NE    . ARG B 2 335  ? 174.684 381.653 243.074 1.00 118.36 ? 335  ARG C NE    1 
ATOM   10241 C CZ    . ARG B 2 335  ? 173.671 382.035 243.840 1.00 118.36 ? 335  ARG C CZ    1 
ATOM   10242 N NH1   . ARG B 2 335  ? 172.415 381.820 243.484 1.00 118.36 ? 335  ARG C NH1   1 
ATOM   10243 N NH2   . ARG B 2 335  ? 173.925 382.650 244.992 1.00 118.36 ? 335  ARG C NH2   1 
ATOM   10244 N N     . ASP B 2 336  ? 176.296 376.680 241.630 1.00 111.55 ? 336  ASP C N     1 
ATOM   10245 C CA    . ASP B 2 336  ? 176.705 375.927 240.447 1.00 111.55 ? 336  ASP C CA    1 
ATOM   10246 C C     . ASP B 2 336  ? 178.218 375.726 240.421 1.00 111.55 ? 336  ASP C C     1 
ATOM   10247 O O     . ASP B 2 336  ? 178.968 376.686 240.206 1.00 111.55 ? 336  ASP C O     1 
ATOM   10248 C CB    . ASP B 2 336  ? 176.246 376.646 239.177 1.00 111.55 ? 336  ASP C CB    1 
ATOM   10249 C CG    . ASP B 2 336  ? 176.338 375.769 237.942 1.00 111.55 ? 336  ASP C CG    1 
ATOM   10250 O OD1   . ASP B 2 336  ? 176.602 374.557 238.084 1.00 111.55 ? 336  ASP C OD1   1 
ATOM   10251 O OD2   . ASP B 2 336  ? 176.146 376.295 236.825 1.00 111.55 ? 336  ASP C OD2   1 
ATOM   10252 N N     . PRO B 2 337  ? 178.708 374.493 240.588 1.00 107.30 ? 337  PRO C N     1 
ATOM   10253 C CA    . PRO B 2 337  ? 180.161 374.277 240.603 1.00 107.30 ? 337  PRO C CA    1 
ATOM   10254 C C     . PRO B 2 337  ? 180.806 374.283 239.227 1.00 107.30 ? 337  PRO C C     1 
ATOM   10255 O O     . PRO B 2 337  ? 182.042 374.273 239.145 1.00 107.30 ? 337  PRO C O     1 
ATOM   10256 C CB    . PRO B 2 337  ? 180.302 372.902 241.269 1.00 107.30 ? 337  PRO C CB    1 
ATOM   10257 C CG    . PRO B 2 337  ? 179.007 372.203 241.002 1.00 107.30 ? 337  PRO C CG    1 
ATOM   10258 C CD    . PRO B 2 337  ? 177.952 373.233 240.682 1.00 107.30 ? 337  PRO C CD    1 
ATOM   10259 N N     . TYR B 2 338  ? 180.020 374.299 238.150 1.00 101.80 ? 338  TYR C N     1 
ATOM   10260 C CA    . TYR B 2 338  ? 180.574 374.320 236.803 1.00 101.80 ? 338  TYR C CA    1 
ATOM   10261 C C     . TYR B 2 338  ? 180.989 375.714 236.350 1.00 101.80 ? 338  TYR C C     1 
ATOM   10262 O O     . TYR B 2 338  ? 181.641 375.838 235.307 1.00 101.80 ? 338  TYR C O     1 
ATOM   10263 C CB    . TYR B 2 338  ? 179.564 373.740 235.810 1.00 101.80 ? 338  TYR C CB    1 
ATOM   10264 N N     . ALA B 2 339  ? 180.623 376.759 237.097 1.00 105.85 ? 339  ALA C N     1 
ATOM   10265 C CA    . ALA B 2 339  ? 180.986 378.117 236.700 1.00 105.85 ? 339  ALA C CA    1 
ATOM   10266 C C     . ALA B 2 339  ? 182.495 378.323 236.736 1.00 105.85 ? 339  ALA C C     1 
ATOM   10267 O O     . ALA B 2 339  ? 183.064 378.959 235.841 1.00 105.85 ? 339  ALA C O     1 
ATOM   10268 C CB    . ALA B 2 339  ? 180.283 379.132 237.602 1.00 105.85 ? 339  ALA C CB    1 
ATOM   10269 N N     . LEU B 2 340  ? 183.160 377.795 237.761 1.00 104.94 ? 340  LEU C N     1 
ATOM   10270 C CA    . LEU B 2 340  ? 184.604 377.950 237.905 1.00 104.94 ? 340  LEU C CA    1 
ATOM   10271 C C     . LEU B 2 340  ? 185.304 376.926 237.020 1.00 104.94 ? 340  LEU C C     1 
ATOM   10272 O O     . LEU B 2 340  ? 185.180 375.716 237.239 1.00 104.94 ? 340  LEU C O     1 
ATOM   10273 C CB    . LEU B 2 340  ? 185.015 377.788 239.366 1.00 104.94 ? 340  LEU C CB    1 
ATOM   10274 N N     . ARG B 2 341  ? 186.032 377.409 236.014 1.00 103.08 ? 341  ARG C N     1 
ATOM   10275 C CA    . ARG B 2 341  ? 186.747 376.506 235.113 1.00 103.08 ? 341  ARG C CA    1 
ATOM   10276 C C     . ARG B 2 341  ? 187.797 375.661 235.826 1.00 103.08 ? 341  ARG C C     1 
ATOM   10277 O O     . ARG B 2 341  ? 187.844 374.443 235.575 1.00 103.08 ? 341  ARG C O     1 
ATOM   10278 C CB    . ARG B 2 341  ? 187.359 377.308 233.959 1.00 103.08 ? 341  ARG C CB    1 
ATOM   10279 N N     . PRO B 2 342  ? 188.673 376.210 236.682 1.00 101.81 ? 342  PRO C N     1 
ATOM   10280 C CA    . PRO B 2 342  ? 189.610 375.328 237.403 1.00 101.81 ? 342  PRO C CA    1 
ATOM   10281 C C     . PRO B 2 342  ? 188.915 374.289 238.266 1.00 101.81 ? 342  PRO C C     1 
ATOM   10282 O O     . PRO B 2 342  ? 189.365 373.138 238.325 1.00 101.81 ? 342  PRO C O     1 
ATOM   10283 C CB    . PRO B 2 342  ? 190.439 376.308 238.245 1.00 101.81 ? 342  PRO C CB    1 
ATOM   10284 C CG    . PRO B 2 342  ? 190.316 377.611 237.547 1.00 101.81 ? 342  PRO C CG    1 
ATOM   10285 C CD    . PRO B 2 342  ? 188.931 377.631 236.985 1.00 101.81 ? 342  PRO C CD    1 
ATOM   10286 N N     . LEU B 2 343  ? 187.818 374.661 238.931 1.00 98.58  ? 343  LEU C N     1 
ATOM   10287 C CA    . LEU B 2 343  ? 187.094 373.699 239.757 1.00 98.58  ? 343  LEU C CA    1 
ATOM   10288 C C     . LEU B 2 343  ? 186.463 372.607 238.902 1.00 98.58  ? 343  LEU C C     1 
ATOM   10289 O O     . LEU B 2 343  ? 186.484 371.426 239.272 1.00 98.58  ? 343  LEU C O     1 
ATOM   10290 C CB    . LEU B 2 343  ? 186.032 374.418 240.589 1.00 98.58  ? 343  LEU C CB    1 
ATOM   10291 C CG    . LEU B 2 343  ? 184.971 373.549 241.268 1.00 98.58  ? 343  LEU C CG    1 
ATOM   10292 C CD1   . LEU B 2 343  ? 185.604 372.652 242.320 1.00 98.58  ? 343  LEU C CD1   1 
ATOM   10293 C CD2   . LEU B 2 343  ? 183.884 374.416 241.884 1.00 98.58  ? 343  LEU C CD2   1 
ATOM   10294 N N     . ARG B 2 344  ? 185.893 372.984 237.755 1.00 95.76  ? 344  ARG C N     1 
ATOM   10295 C CA    . ARG B 2 344  ? 185.322 371.991 236.851 1.00 95.76  ? 344  ARG C CA    1 
ATOM   10296 C C     . ARG B 2 344  ? 186.394 371.043 236.331 1.00 95.76  ? 344  ARG C C     1 
ATOM   10297 O O     . ARG B 2 344  ? 186.179 369.828 236.261 1.00 95.76  ? 344  ARG C O     1 
ATOM   10298 C CB    . ARG B 2 344  ? 184.609 372.686 235.691 1.00 95.76  ? 344  ARG C CB    1 
ATOM   10299 C CG    . ARG B 2 344  ? 184.050 371.736 234.645 1.00 95.76  ? 344  ARG C CG    1 
ATOM   10300 C CD    . ARG B 2 344  ? 184.690 371.974 233.288 1.00 95.76  ? 344  ARG C CD    1 
ATOM   10301 N NE    . ARG B 2 344  ? 184.365 373.292 232.755 1.00 95.76  ? 344  ARG C NE    1 
ATOM   10302 C CZ    . ARG B 2 344  ? 184.657 373.697 231.527 1.00 95.76  ? 344  ARG C CZ    1 
ATOM   10303 N NH1   . ARG B 2 344  ? 185.282 372.907 230.669 1.00 95.76  ? 344  ARG C NH1   1 
ATOM   10304 N NH2   . ARG B 2 344  ? 184.314 374.925 231.150 1.00 95.76  ? 344  ARG C NH2   1 
ATOM   10305 N N     . ARG B 2 345  ? 187.562 371.580 235.970 1.00 88.43  ? 345  ARG C N     1 
ATOM   10306 C CA    . ARG B 2 345  ? 188.655 370.727 235.516 1.00 88.43  ? 345  ARG C CA    1 
ATOM   10307 C C     . ARG B 2 345  ? 189.111 369.783 236.621 1.00 88.43  ? 345  ARG C C     1 
ATOM   10308 O O     . ARG B 2 345  ? 189.373 368.602 236.369 1.00 88.43  ? 345  ARG C O     1 
ATOM   10309 C CB    . ARG B 2 345  ? 189.821 371.585 235.025 1.00 88.43  ? 345  ARG C CB    1 
ATOM   10310 N N     . LEU B 2 346  ? 189.206 370.286 237.855 1.00 84.43  ? 346  LEU C N     1 
ATOM   10311 C CA    . LEU B 2 346  ? 189.633 369.446 238.969 1.00 84.43  ? 346  LEU C CA    1 
ATOM   10312 C C     . LEU B 2 346  ? 188.639 368.320 239.232 1.00 84.43  ? 346  LEU C C     1 
ATOM   10313 O O     . LEU B 2 346  ? 189.037 367.166 239.431 1.00 84.43  ? 346  LEU C O     1 
ATOM   10314 C CB    . LEU B 2 346  ? 189.824 370.297 240.224 1.00 84.43  ? 346  LEU C CB    1 
ATOM   10315 N N     . ILE B 2 347  ? 187.340 368.632 239.238 1.00 82.54  ? 347  ILE C N     1 
ATOM   10316 C CA    . ILE B 2 347  ? 186.348 367.595 239.508 1.00 82.54  ? 347  ILE C CA    1 
ATOM   10317 C C     . ILE B 2 347  ? 186.289 366.595 238.358 1.00 82.54  ? 347  ILE C C     1 
ATOM   10318 O O     . ILE B 2 347  ? 186.098 365.393 238.578 1.00 82.54  ? 347  ILE C O     1 
ATOM   10319 C CB    . ILE B 2 347  ? 184.968 368.211 239.816 1.00 82.54  ? 347  ILE C CB    1 
ATOM   10320 C CG1   . ILE B 2 347  ? 184.384 368.927 238.597 1.00 82.54  ? 347  ILE C CG1   1 
ATOM   10321 C CG2   . ILE B 2 347  ? 185.055 369.149 241.013 1.00 82.54  ? 347  ILE C CG2   1 
ATOM   10322 C CD1   . ILE B 2 347  ? 182.871 368.957 238.573 1.00 82.54  ? 347  ILE C CD1   1 
ATOM   10323 N N     . ASP B 2 348  ? 186.462 367.062 237.116 1.00 77.85  ? 348  ASP C N     1 
ATOM   10324 C CA    . ASP B 2 348  ? 186.504 366.141 235.985 1.00 77.85  ? 348  ASP C CA    1 
ATOM   10325 C C     . ASP B 2 348  ? 187.708 365.210 236.077 1.00 77.85  ? 348  ASP C C     1 
ATOM   10326 O O     . ASP B 2 348  ? 187.594 364.007 235.812 1.00 77.85  ? 348  ASP C O     1 
ATOM   10327 C CB    . ASP B 2 348  ? 186.526 366.922 234.672 1.00 77.85  ? 348  ASP C CB    1 
ATOM   10328 N N     . ALA B 2 349  ? 188.871 365.751 236.450 1.00 78.13  ? 349  ALA C N     1 
ATOM   10329 C CA    . ALA B 2 349  ? 190.057 364.917 236.614 1.00 78.13  ? 349  ALA C CA    1 
ATOM   10330 C C     . ALA B 2 349  ? 189.866 363.903 237.734 1.00 78.13  ? 349  ALA C C     1 
ATOM   10331 O O     . ALA B 2 349  ? 190.275 362.743 237.607 1.00 78.13  ? 349  ALA C O     1 
ATOM   10332 C CB    . ALA B 2 349  ? 191.281 365.792 236.883 1.00 78.13  ? 349  ALA C CB    1 
ATOM   10333 N N     . TYR B 2 350  ? 189.250 364.323 238.842 1.00 80.48  ? 350  TYR C N     1 
ATOM   10334 C CA    . TYR B 2 350  ? 188.991 363.395 239.939 1.00 80.48  ? 350  TYR C CA    1 
ATOM   10335 C C     . TYR B 2 350  ? 188.032 362.289 239.513 1.00 80.48  ? 350  TYR C C     1 
ATOM   10336 O O     . TYR B 2 350  ? 188.233 361.117 239.855 1.00 80.48  ? 350  TYR C O     1 
ATOM   10337 C CB    . TYR B 2 350  ? 188.438 364.153 241.147 1.00 80.48  ? 350  TYR C CB    1 
ATOM   10338 C CG    . TYR B 2 350  ? 189.495 364.558 242.149 1.00 80.48  ? 350  TYR C CG    1 
ATOM   10339 C CD1   . TYR B 2 350  ? 190.571 365.351 241.770 1.00 80.48  ? 350  TYR C CD1   1 
ATOM   10340 C CD2   . TYR B 2 350  ? 189.418 364.149 243.474 1.00 80.48  ? 350  TYR C CD2   1 
ATOM   10341 C CE1   . TYR B 2 350  ? 191.540 365.724 242.681 1.00 80.48  ? 350  TYR C CE1   1 
ATOM   10342 C CE2   . TYR B 2 350  ? 190.383 364.517 244.393 1.00 80.48  ? 350  TYR C CE2   1 
ATOM   10343 C CZ    . TYR B 2 350  ? 191.442 365.305 243.991 1.00 80.48  ? 350  TYR C CZ    1 
ATOM   10344 O OH    . TYR B 2 350  ? 192.405 365.675 244.901 1.00 80.48  ? 350  TYR C OH    1 
ATOM   10345 N N     . ALA B 2 351  ? 186.983 362.643 238.766 1.00 75.62  ? 351  ALA C N     1 
ATOM   10346 C CA    . ALA B 2 351  ? 186.044 361.637 238.279 1.00 75.62  ? 351  ALA C CA    1 
ATOM   10347 C C     . ALA B 2 351  ? 186.725 360.661 237.329 1.00 75.62  ? 351  ALA C C     1 
ATOM   10348 O O     . ALA B 2 351  ? 186.470 359.452 237.382 1.00 75.62  ? 351  ALA C O     1 
ATOM   10349 C CB    . ALA B 2 351  ? 184.857 362.314 237.595 1.00 75.62  ? 351  ALA C CB    1 
ATOM   10350 N N     . PHE B 2 352  ? 187.588 361.168 236.445 1.00 78.32  ? 352  PHE C N     1 
ATOM   10351 C CA    . PHE B 2 352  ? 188.315 360.288 235.537 1.00 78.32  ? 352  PHE C CA    1 
ATOM   10352 C C     . PHE B 2 352  ? 189.256 359.363 236.298 1.00 78.32  ? 352  PHE C C     1 
ATOM   10353 O O     . PHE B 2 352  ? 189.376 358.179 235.967 1.00 78.32  ? 352  PHE C O     1 
ATOM   10354 C CB    . PHE B 2 352  ? 189.085 361.112 234.506 1.00 78.32  ? 352  PHE C CB    1 
ATOM   10355 C CG    . PHE B 2 352  ? 188.518 361.026 233.119 1.00 78.32  ? 352  PHE C CG    1 
ATOM   10356 C CD1   . PHE B 2 352  ? 187.287 361.587 232.822 1.00 78.32  ? 352  PHE C CD1   1 
ATOM   10357 C CD2   . PHE B 2 352  ? 189.214 360.379 232.111 1.00 78.32  ? 352  PHE C CD2   1 
ATOM   10358 C CE1   . PHE B 2 352  ? 186.762 361.507 231.547 1.00 78.32  ? 352  PHE C CE1   1 
ATOM   10359 C CE2   . PHE B 2 352  ? 188.694 360.295 230.833 1.00 78.32  ? 352  PHE C CE2   1 
ATOM   10360 C CZ    . PHE B 2 352  ? 187.466 360.860 230.551 1.00 78.32  ? 352  PHE C CZ    1 
ATOM   10361 N N     . ARG B 2 353  ? 189.934 359.886 237.323 1.00 67.83  ? 353  ARG C N     1 
ATOM   10362 C CA    . ARG B 2 353  ? 190.840 359.057 238.111 1.00 67.83  ? 353  ARG C CA    1 
ATOM   10363 C C     . ARG B 2 353  ? 190.076 358.003 238.903 1.00 67.83  ? 353  ARG C C     1 
ATOM   10364 O O     . ARG B 2 353  ? 190.588 356.901 239.138 1.00 67.83  ? 353  ARG C O     1 
ATOM   10365 C CB    . ARG B 2 353  ? 191.672 359.933 239.047 1.00 67.83  ? 353  ARG C CB    1 
ATOM   10366 N N     . ILE B 2 354  ? 188.853 358.325 239.331 1.00 66.84  ? 354  ILE C N     1 
ATOM   10367 C CA    . ILE B 2 354  ? 188.049 357.363 240.081 1.00 66.84  ? 354  ILE C CA    1 
ATOM   10368 C C     . ILE B 2 354  ? 187.726 356.150 239.216 1.00 66.84  ? 354  ILE C C     1 
ATOM   10369 O O     . ILE B 2 354  ? 187.820 355.002 239.668 1.00 66.84  ? 354  ILE C O     1 
ATOM   10370 C CB    . ILE B 2 354  ? 186.775 358.042 240.620 1.00 66.84  ? 354  ILE C CB    1 
ATOM   10371 C CG1   . ILE B 2 354  ? 187.055 358.710 241.968 1.00 66.84  ? 354  ILE C CG1   1 
ATOM   10372 C CG2   . ILE B 2 354  ? 185.643 357.035 240.763 1.00 66.84  ? 354  ILE C CG2   1 
ATOM   10373 C CD1   . ILE B 2 354  ? 187.038 357.758 243.145 1.00 66.84  ? 354  ILE C CD1   1 
ATOM   10374 N N     . TYR B 2 355  ? 187.359 356.382 237.956 1.00 70.05  ? 355  TYR C N     1 
ATOM   10375 C CA    . TYR B 2 355  ? 187.031 355.319 237.010 1.00 70.05  ? 355  TYR C CA    1 
ATOM   10376 C C     . TYR B 2 355  ? 188.036 355.260 235.862 1.00 70.05  ? 355  TYR C C     1 
ATOM   10377 O O     . TYR B 2 355  ? 187.663 355.125 234.696 1.00 70.05  ? 355  TYR C O     1 
ATOM   10378 C CB    . TYR B 2 355  ? 185.617 355.492 236.460 1.00 70.05  ? 355  TYR C CB    1 
ATOM   10379 C CG    . TYR B 2 355  ? 184.533 355.574 237.513 1.00 70.05  ? 355  TYR C CG    1 
ATOM   10380 C CD1   . TYR B 2 355  ? 184.201 354.467 238.282 1.00 70.05  ? 355  TYR C CD1   1 
ATOM   10381 C CD2   . TYR B 2 355  ? 183.825 356.751 237.719 1.00 70.05  ? 355  TYR C CD2   1 
ATOM   10382 C CE1   . TYR B 2 355  ? 183.206 354.534 239.240 1.00 70.05  ? 355  TYR C CE1   1 
ATOM   10383 C CE2   . TYR B 2 355  ? 182.827 356.827 238.674 1.00 70.05  ? 355  TYR C CE2   1 
ATOM   10384 C CZ    . TYR B 2 355  ? 182.522 355.716 239.431 1.00 70.05  ? 355  TYR C CZ    1 
ATOM   10385 O OH    . TYR B 2 355  ? 181.531 355.787 240.383 1.00 70.05  ? 355  TYR C OH    1 
ATOM   10386 N N     . GLY B 2 356  ? 189.325 355.361 236.181 1.00 77.10  ? 356  GLY C N     1 
ATOM   10387 C CA    . GLY B 2 356  ? 190.365 355.336 235.172 1.00 77.10  ? 356  GLY C CA    1 
ATOM   10388 C C     . GLY B 2 356  ? 190.734 353.973 234.640 1.00 77.10  ? 356  GLY C C     1 
ATOM   10389 O O     . GLY B 2 356  ? 191.562 353.878 233.730 1.00 77.10  ? 356  GLY C O     1 
ATOM   10390 N N     . HIS B 2 357  ? 190.144 352.908 235.177 1.00 77.73  ? 357  HIS C N     1 
ATOM   10391 C CA    . HIS B 2 357  ? 190.418 351.548 234.738 1.00 77.73  ? 357  HIS C CA    1 
ATOM   10392 C C     . HIS B 2 357  ? 189.360 351.015 233.780 1.00 77.73  ? 357  HIS C C     1 
ATOM   10393 O O     . HIS B 2 357  ? 189.342 349.812 233.500 1.00 77.73  ? 357  HIS C O     1 
ATOM   10394 C CB    . HIS B 2 357  ? 190.555 350.623 235.952 1.00 77.73  ? 357  HIS C CB    1 
ATOM   10395 C CG    . HIS B 2 357  ? 189.337 350.574 236.824 1.00 77.73  ? 357  HIS C CG    1 
ATOM   10396 N ND1   . HIS B 2 357  ? 188.094 350.205 236.355 1.00 77.73  ? 357  HIS C ND1   1 
ATOM   10397 C CD2   . HIS B 2 357  ? 189.174 350.850 238.139 1.00 77.73  ? 357  HIS C CD2   1 
ATOM   10398 C CE1   . HIS B 2 357  ? 187.219 350.255 237.344 1.00 77.73  ? 357  HIS C CE1   1 
ATOM   10399 N NE2   . HIS B 2 357  ? 187.849 350.644 238.437 1.00 77.73  ? 357  HIS C NE2   1 
ATOM   10400 N N     . TRP B 2 358  ? 188.483 351.878 233.274 1.00 80.82  ? 358  TRP C N     1 
ATOM   10401 C CA    . TRP B 2 358  ? 187.372 351.474 232.421 1.00 80.82  ? 358  TRP C CA    1 
ATOM   10402 C C     . TRP B 2 358  ? 187.379 352.258 231.117 1.00 80.82  ? 358  TRP C C     1 
ATOM   10403 O O     . TRP B 2 358  ? 186.327 352.617 230.579 1.00 80.82  ? 358  TRP C O     1 
ATOM   10404 C CB    . TRP B 2 358  ? 186.044 351.644 233.152 1.00 80.82  ? 358  TRP C CB    1 
ATOM   10405 C CG    . TRP B 2 358  ? 185.640 350.431 233.924 1.00 80.82  ? 358  TRP C CG    1 
ATOM   10406 C CD1   . TRP B 2 358  ? 186.303 349.240 233.984 1.00 80.82  ? 358  TRP C CD1   1 
ATOM   10407 C CD2   . TRP B 2 358  ? 184.496 350.297 234.774 1.00 80.82  ? 358  TRP C CD2   1 
ATOM   10408 N NE1   . TRP B 2 358  ? 185.634 348.367 234.805 1.00 80.82  ? 358  TRP C NE1   1 
ATOM   10409 C CE2   . TRP B 2 358  ? 184.522 348.992 235.305 1.00 80.82  ? 358  TRP C CE2   1 
ATOM   10410 C CE3   . TRP B 2 358  ? 183.450 351.150 235.132 1.00 80.82  ? 358  TRP C CE3   1 
ATOM   10411 C CZ2   . TRP B 2 358  ? 183.541 348.521 236.174 1.00 80.82  ? 358  TRP C CZ2   1 
ATOM   10412 C CZ3   . TRP B 2 358  ? 182.480 350.682 235.995 1.00 80.82  ? 358  TRP C CZ3   1 
ATOM   10413 C CH2   . TRP B 2 358  ? 182.530 349.379 236.506 1.00 80.82  ? 358  TRP C CH2   1 
ATOM   10414 N N     . VAL B 2 359  ? 188.568 352.536 230.589 1.00 86.51  ? 359  VAL C N     1 
ATOM   10415 C CA    . VAL B 2 359  ? 188.728 353.229 229.311 1.00 86.51  ? 359  VAL C CA    1 
ATOM   10416 C C     . VAL B 2 359  ? 189.647 352.366 228.449 1.00 86.51  ? 359  VAL C C     1 
ATOM   10417 O O     . VAL B 2 359  ? 190.875 352.500 228.482 1.00 86.51  ? 359  VAL C O     1 
ATOM   10418 C CB    . VAL B 2 359  ? 189.271 354.654 229.474 1.00 86.51  ? 359  VAL C CB    1 
ATOM   10419 C CG1   . VAL B 2 359  ? 188.166 355.575 229.960 1.00 86.51  ? 359  VAL C CG1   1 
ATOM   10420 C CG2   . VAL B 2 359  ? 190.417 354.685 230.479 1.00 86.51  ? 359  VAL C CG2   1 
ATOM   10421 N N     . LYS B 2 360  ? 189.053 351.468 227.665 1.00 95.39  ? 360  LYS C N     1 
ATOM   10422 C CA    . LYS B 2 360  ? 189.796 350.559 226.804 1.00 95.39  ? 360  LYS C CA    1 
ATOM   10423 C C     . LYS B 2 360  ? 189.129 350.525 225.436 1.00 95.39  ? 360  LYS C C     1 
ATOM   10424 O O     . LYS B 2 360  ? 188.256 351.342 225.125 1.00 95.39  ? 360  LYS C O     1 
ATOM   10425 C CB    . LYS B 2 360  ? 189.879 349.150 227.408 1.00 95.39  ? 360  LYS C CB    1 
ATOM   10426 C CG    . LYS B 2 360  ? 190.245 349.109 228.885 1.00 95.39  ? 360  LYS C CG    1 
ATOM   10427 C CD    . LYS B 2 360  ? 190.575 347.693 229.333 1.00 95.39  ? 360  LYS C CD    1 
ATOM   10428 C CE    . LYS B 2 360  ? 190.799 347.624 230.836 1.00 95.39  ? 360  LYS C CE    1 
ATOM   10429 N NZ    . LYS B 2 360  ? 190.386 348.878 231.522 1.00 95.39  ? 360  LYS C NZ    1 
ATOM   10430 N N     . LYS B 2 361  ? 189.552 349.570 224.612 1.00 101.84 ? 361  LYS C N     1 
ATOM   10431 C CA    . LYS B 2 361  ? 188.987 349.429 223.278 1.00 101.84 ? 361  LYS C CA    1 
ATOM   10432 C C     . LYS B 2 361  ? 187.531 348.987 223.354 1.00 101.84 ? 361  LYS C C     1 
ATOM   10433 O O     . LYS B 2 361  ? 187.157 348.157 224.187 1.00 101.84 ? 361  LYS C O     1 
ATOM   10434 C CB    . LYS B 2 361  ? 189.805 348.428 222.462 1.00 101.84 ? 361  LYS C CB    1 
ATOM   10435 C CG    . LYS B 2 361  ? 191.304 348.681 222.499 1.00 101.84 ? 361  LYS C CG    1 
ATOM   10436 C CD    . LYS B 2 361  ? 192.092 347.400 222.287 1.00 101.84 ? 361  LYS C CD    1 
ATOM   10437 C CE    . LYS B 2 361  ? 193.544 347.574 222.702 1.00 101.84 ? 361  LYS C CE    1 
ATOM   10438 N NZ    . LYS B 2 361  ? 194.412 347.936 221.547 1.00 101.84 ? 361  LYS C NZ    1 
ATOM   10439 N N     . GLY B 2 362  ? 186.708 349.550 222.473 1.00 106.12 ? 362  GLY C N     1 
ATOM   10440 C CA    . GLY B 2 362  ? 185.296 349.223 222.439 1.00 106.12 ? 362  GLY C CA    1 
ATOM   10441 C C     . GLY B 2 362  ? 184.400 350.442 222.380 1.00 106.12 ? 362  GLY C C     1 
ATOM   10442 O O     . GLY B 2 362  ? 184.604 351.411 223.117 1.00 106.12 ? 362  GLY C O     1 
ATOM   10443 N N     . GLN B 2 363  ? 183.398 350.404 221.498 1.00 106.41 ? 363  GLN C N     1 
ATOM   10444 C CA    . GLN B 2 363  ? 182.466 351.518 221.371 1.00 106.41 ? 363  GLN C CA    1 
ATOM   10445 C C     . GLN B 2 363  ? 181.491 351.589 222.540 1.00 106.41 ? 363  GLN C C     1 
ATOM   10446 O O     . GLN B 2 363  ? 180.994 352.678 222.851 1.00 106.41 ? 363  GLN C O     1 
ATOM   10447 C CB    . GLN B 2 363  ? 181.734 351.413 220.022 1.00 106.41 ? 363  GLN C CB    1 
ATOM   10448 C CG    . GLN B 2 363  ? 180.294 351.937 219.948 1.00 106.41 ? 363  GLN C CG    1 
ATOM   10449 C CD    . GLN B 2 363  ? 179.276 351.003 220.583 1.00 106.41 ? 363  GLN C CD    1 
ATOM   10450 O OE1   . GLN B 2 363  ? 179.454 349.785 220.590 1.00 106.41 ? 363  GLN C OE1   1 
ATOM   10451 N NE2   . GLN B 2 363  ? 178.203 351.573 221.120 1.00 106.41 ? 363  GLN C NE2   1 
ATOM   10452 N N     . GLN B 2 364  ? 181.223 350.461 223.203 1.00 103.56 ? 364  GLN C N     1 
ATOM   10453 C CA    . GLN B 2 364  ? 180.240 350.443 224.282 1.00 103.56 ? 364  GLN C CA    1 
ATOM   10454 C C     . GLN B 2 364  ? 180.658 351.348 225.435 1.00 103.56 ? 364  GLN C C     1 
ATOM   10455 O O     . GLN B 2 364  ? 179.826 352.063 226.006 1.00 103.56 ? 364  GLN C O     1 
ATOM   10456 C CB    . GLN B 2 364  ? 180.029 349.011 224.773 1.00 103.56 ? 364  GLN C CB    1 
ATOM   10457 C CG    . GLN B 2 364  ? 178.911 348.850 225.794 1.00 103.56 ? 364  GLN C CG    1 
ATOM   10458 C CD    . GLN B 2 364  ? 177.664 349.637 225.436 1.00 103.56 ? 364  GLN C CD    1 
ATOM   10459 O OE1   . GLN B 2 364  ? 177.182 349.583 224.304 1.00 103.56 ? 364  GLN C OE1   1 
ATOM   10460 N NE2   . GLN B 2 364  ? 177.134 350.376 226.404 1.00 103.56 ? 364  GLN C NE2   1 
ATOM   10461 N N     . GLN B 2 365  ? 181.938 351.329 225.795 1.00 100.10 ? 365  GLN C N     1 
ATOM   10462 C CA    . GLN B 2 365  ? 182.469 352.157 226.870 1.00 100.10 ? 365  GLN C CA    1 
ATOM   10463 C C     . GLN B 2 365  ? 183.597 353.022 226.326 1.00 100.10 ? 365  GLN C C     1 
ATOM   10464 O O     . GLN B 2 365  ? 184.556 352.504 225.745 1.00 100.10 ? 365  GLN C O     1 
ATOM   10465 C CB    . GLN B 2 365  ? 182.968 351.295 228.032 1.00 100.10 ? 365  GLN C CB    1 
ATOM   10466 C CG    . GLN B 2 365  ? 182.001 350.197 228.445 1.00 100.10 ? 365  GLN C CG    1 
ATOM   10467 C CD    . GLN B 2 365  ? 182.706 348.907 228.808 1.00 100.10 ? 365  GLN C CD    1 
ATOM   10468 O OE1   . GLN B 2 365  ? 183.474 348.362 228.016 1.00 100.10 ? 365  GLN C OE1   1 
ATOM   10469 N NE2   . GLN B 2 365  ? 182.449 348.410 230.013 1.00 100.10 ? 365  GLN C NE2   1 
ATOM   10470 N N     . ASN B 2 366  ? 183.482 354.332 226.520 1.00 90.23  ? 366  ASN C N     1 
ATOM   10471 C CA    . ASN B 2 366  ? 184.472 355.277 226.023 1.00 90.23  ? 366  ASN C CA    1 
ATOM   10472 C C     . ASN B 2 366  ? 184.491 356.491 226.947 1.00 90.23  ? 366  ASN C C     1 
ATOM   10473 O O     . ASN B 2 366  ? 183.881 356.486 228.020 1.00 90.23  ? 366  ASN C O     1 
ATOM   10474 C CB    . ASN B 2 366  ? 184.170 355.660 224.568 1.00 90.23  ? 366  ASN C CB    1 
ATOM   10475 C CG    . ASN B 2 366  ? 182.690 355.869 224.314 1.00 90.23  ? 366  ASN C CG    1 
ATOM   10476 O OD1   . ASN B 2 366  ? 181.848 355.157 224.861 1.00 90.23  ? 366  ASN C OD1   1 
ATOM   10477 N ND2   . ASN B 2 366  ? 182.365 356.850 223.480 1.00 90.23  ? 366  ASN C ND2   1 
ATOM   10478 N N     . ARG B 2 367  ? 185.206 357.536 226.524 1.00 85.43  ? 367  ARG C N     1 
ATOM   10479 C CA    . ARG B 2 367  ? 185.303 358.749 227.331 1.00 85.43  ? 367  ARG C CA    1 
ATOM   10480 C C     . ARG B 2 367  ? 183.950 359.436 227.471 1.00 85.43  ? 367  ARG C C     1 
ATOM   10481 O O     . ARG B 2 367  ? 183.606 359.931 228.550 1.00 85.43  ? 367  ARG C O     1 
ATOM   10482 C CB    . ARG B 2 367  ? 186.325 359.705 226.718 1.00 85.43  ? 367  ARG C CB    1 
ATOM   10483 C CG    . ARG B 2 367  ? 187.432 359.017 225.941 1.00 85.43  ? 367  ARG C CG    1 
ATOM   10484 C CD    . ARG B 2 367  ? 188.393 360.035 225.349 1.00 85.43  ? 367  ARG C CD    1 
ATOM   10485 N NE    . ARG B 2 367  ? 189.056 360.825 226.380 1.00 85.43  ? 367  ARG C NE    1 
ATOM   10486 C CZ    . ARG B 2 367  ? 189.990 360.366 227.201 1.00 85.43  ? 367  ARG C CZ    1 
ATOM   10487 N NH1   . ARG B 2 367  ? 190.422 359.117 227.130 1.00 85.43  ? 367  ARG C NH1   1 
ATOM   10488 N NH2   . ARG B 2 367  ? 190.511 361.182 228.112 1.00 85.43  ? 367  ARG C NH2   1 
ATOM   10489 N N     . ALA B 2 368  ? 183.171 359.482 226.387 1.00 85.04  ? 368  ALA C N     1 
ATOM   10490 C CA    . ALA B 2 368  ? 181.887 360.172 226.420 1.00 85.04  ? 368  ALA C CA    1 
ATOM   10491 C C     . ALA B 2 368  ? 180.879 359.484 227.331 1.00 85.04  ? 368  ALA C C     1 
ATOM   10492 O O     . ALA B 2 368  ? 179.886 360.110 227.719 1.00 85.04  ? 368  ALA C O     1 
ATOM   10493 C CB    . ALA B 2 368  ? 181.319 360.288 225.005 1.00 85.04  ? 368  ALA C CB    1 
ATOM   10494 N N     . ALA B 2 369  ? 181.105 358.214 227.675 1.00 83.16  ? 369  ALA C N     1 
ATOM   10495 C CA    . ALA B 2 369  ? 180.199 357.522 228.585 1.00 83.16  ? 369  ALA C CA    1 
ATOM   10496 C C     . ALA B 2 369  ? 180.224 358.149 229.974 1.00 83.16  ? 369  ALA C C     1 
ATOM   10497 O O     . ALA B 2 369  ? 179.182 358.264 230.631 1.00 83.16  ? 369  ALA C O     1 
ATOM   10498 C CB    . ALA B 2 369  ? 180.559 356.038 228.658 1.00 83.16  ? 369  ALA C CB    1 
ATOM   10499 N N     . LEU B 2 370  ? 181.406 358.559 230.439 1.00 79.06  ? 370  LEU C N     1 
ATOM   10500 C CA    . LEU B 2 370  ? 181.529 359.148 231.768 1.00 79.06  ? 370  LEU C CA    1 
ATOM   10501 C C     . LEU B 2 370  ? 180.879 360.522 231.863 1.00 79.06  ? 370  LEU C C     1 
ATOM   10502 O O     . LEU B 2 370  ? 180.631 360.999 232.976 1.00 79.06  ? 370  LEU C O     1 
ATOM   10503 C CB    . LEU B 2 370  ? 183.003 359.244 232.167 1.00 79.06  ? 370  LEU C CB    1 
ATOM   10504 C CG    . LEU B 2 370  ? 183.571 358.116 233.033 1.00 79.06  ? 370  LEU C CG    1 
ATOM   10505 C CD1   . LEU B 2 370  ? 183.366 356.758 232.376 1.00 79.06  ? 370  LEU C CD1   1 
ATOM   10506 C CD2   . LEU B 2 370  ? 185.045 358.356 233.324 1.00 79.06  ? 370  LEU C CD2   1 
ATOM   10507 N N     . PHE B 2 371  ? 180.599 361.167 230.735 1.00 78.34  ? 371  PHE C N     1 
ATOM   10508 C CA    . PHE B 2 371  ? 179.994 362.492 230.715 1.00 78.34  ? 371  PHE C CA    1 
ATOM   10509 C C     . PHE B 2 371  ? 178.525 362.380 230.328 1.00 78.34  ? 371  PHE C C     1 
ATOM   10510 O O     . PHE B 2 371  ? 178.187 361.719 229.341 1.00 78.34  ? 371  PHE C O     1 
ATOM   10511 C CB    . PHE B 2 371  ? 180.725 363.414 229.738 1.00 78.34  ? 371  PHE C CB    1 
ATOM   10512 C CG    . PHE B 2 371  ? 182.122 363.763 230.162 1.00 78.34  ? 371  PHE C CG    1 
ATOM   10513 C CD1   . PHE B 2 371  ? 182.344 364.649 231.203 1.00 78.34  ? 371  PHE C CD1   1 
ATOM   10514 C CD2   . PHE B 2 371  ? 183.215 363.210 229.515 1.00 78.34  ? 371  PHE C CD2   1 
ATOM   10515 C CE1   . PHE B 2 371  ? 183.630 364.974 231.594 1.00 78.34  ? 371  PHE C CE1   1 
ATOM   10516 C CE2   . PHE B 2 371  ? 184.502 363.531 229.901 1.00 78.34  ? 371  PHE C CE2   1 
ATOM   10517 C CZ    . PHE B 2 371  ? 184.710 364.414 230.942 1.00 78.34  ? 371  PHE C CZ    1 
ATOM   10518 N N     . GLU B 2 372  ? 177.658 363.026 231.107 1.00 75.68  ? 372  GLU C N     1 
ATOM   10519 C CA    . GLU B 2 372  ? 176.217 363.048 230.851 1.00 75.68  ? 372  GLU C CA    1 
ATOM   10520 C C     . GLU B 2 372  ? 175.759 364.503 230.882 1.00 75.68  ? 372  GLU C C     1 
ATOM   10521 O O     . GLU B 2 372  ? 175.321 365.005 231.921 1.00 75.68  ? 372  GLU C O     1 
ATOM   10522 C CB    . GLU B 2 372  ? 175.463 362.196 231.868 1.00 75.68  ? 372  GLU C CB    1 
ATOM   10523 N N     . ASN B 2 373  ? 175.862 365.179 229.736 1.00 79.00  ? 373  ASN C N     1 
ATOM   10524 C CA    . ASN B 2 373  ? 175.404 366.560 229.644 1.00 79.00  ? 373  ASN C CA    1 
ATOM   10525 C C     . ASN B 2 373  ? 173.885 366.647 229.557 1.00 79.00  ? 373  ASN C C     1 
ATOM   10526 O O     . ASN B 2 373  ? 173.295 367.613 230.056 1.00 79.00  ? 373  ASN C O     1 
ATOM   10527 C CB    . ASN B 2 373  ? 176.042 367.244 228.433 1.00 79.00  ? 373  ASN C CB    1 
ATOM   10528 C CG    . ASN B 2 373  ? 175.633 368.699 228.299 1.00 79.00  ? 373  ASN C CG    1 
ATOM   10529 O OD1   . ASN B 2 373  ? 175.340 369.369 229.289 1.00 79.00  ? 373  ASN C OD1   1 
ATOM   10530 N ND2   . ASN B 2 373  ? 175.610 369.195 227.067 1.00 79.00  ? 373  ASN C ND2   1 
ATOM   10531 N N     . THR B 2 374  ? 173.244 365.659 228.939 1.00 83.01  ? 374  THR C N     1 
ATOM   10532 C CA    . THR B 2 374  ? 171.797 365.665 228.822 1.00 83.01  ? 374  THR C CA    1 
ATOM   10533 C C     . THR B 2 374  ? 171.151 365.496 230.198 1.00 83.01  ? 374  THR C C     1 
ATOM   10534 O O     . THR B 2 374  ? 171.682 364.791 231.060 1.00 83.01  ? 374  THR C O     1 
ATOM   10535 C CB    . THR B 2 374  ? 171.331 364.546 227.893 1.00 83.01  ? 374  THR C CB    1 
ATOM   10536 O OG1   . THR B 2 374  ? 171.908 363.303 228.311 1.00 83.01  ? 374  THR C OG1   1 
ATOM   10537 C CG2   . THR B 2 374  ? 171.749 364.837 226.459 1.00 83.01  ? 374  THR C CG2   1 
ATOM   10538 N N     . PRO B 2 375  ? 170.002 366.135 230.428 1.00 91.46  ? 375  PRO C N     1 
ATOM   10539 C CA    . PRO B 2 375  ? 169.327 365.993 231.725 1.00 91.46  ? 375  PRO C CA    1 
ATOM   10540 C C     . PRO B 2 375  ? 168.529 364.697 231.782 1.00 91.46  ? 375  PRO C C     1 
ATOM   10541 O O     . PRO B 2 375  ? 167.794 364.362 230.850 1.00 91.46  ? 375  PRO C O     1 
ATOM   10542 C CB    . PRO B 2 375  ? 168.411 367.220 231.789 1.00 91.46  ? 375  PRO C CB    1 
ATOM   10543 C CG    . PRO B 2 375  ? 168.192 367.627 230.361 1.00 91.46  ? 375  PRO C CG    1 
ATOM   10544 C CD    . PRO B 2 375  ? 169.245 366.984 229.492 1.00 91.46  ? 375  PRO C CD    1 
ATOM   10545 N N     . LYS B 2 376  ? 168.681 363.967 232.888 1.00 101.58 ? 376  LYS C N     1 
ATOM   10546 C CA    . LYS B 2 376  ? 167.986 362.694 233.084 1.00 101.58 ? 376  LYS C CA    1 
ATOM   10547 C C     . LYS B 2 376  ? 166.574 362.968 233.605 1.00 101.58 ? 376  LYS C C     1 
ATOM   10548 O O     . LYS B 2 376  ? 166.251 362.785 234.780 1.00 101.58 ? 376  LYS C O     1 
ATOM   10549 C CB    . LYS B 2 376  ? 168.772 361.797 234.029 1.00 101.58 ? 376  LYS C CB    1 
ATOM   10550 C CG    . LYS B 2 376  ? 168.439 360.320 233.904 1.00 101.58 ? 376  LYS C CG    1 
ATOM   10551 C CD    . LYS B 2 376  ? 169.417 359.468 234.696 1.00 101.58 ? 376  LYS C CD    1 
ATOM   10552 C CE    . LYS B 2 376  ? 170.849 359.723 234.256 1.00 101.58 ? 376  LYS C CE    1 
ATOM   10553 N NZ    . LYS B 2 376  ? 171.162 359.051 232.965 1.00 101.58 ? 376  LYS C NZ    1 
ATOM   10554 N N     . ALA B 2 377  ? 165.719 363.420 232.688 1.00 118.63 ? 377  ALA C N     1 
ATOM   10555 C CA    . ALA B 2 377  ? 164.345 363.766 233.025 1.00 118.63 ? 377  ALA C CA    1 
ATOM   10556 C C     . ALA B 2 377  ? 163.361 363.050 232.109 1.00 118.63 ? 377  ALA C C     1 
ATOM   10557 O O     . ALA B 2 377  ? 163.741 362.133 231.374 1.00 118.63 ? 377  ALA C O     1 
ATOM   10558 C CB    . ALA B 2 377  ? 164.139 365.280 232.952 1.00 118.63 ? 377  ALA C CB    1 
ATOM   10559 N N     . VAL B 2 378  ? 162.090 363.460 232.158 1.00 127.59 ? 378  VAL C N     1 
ATOM   10560 C CA    . VAL B 2 378  ? 161.059 362.831 231.336 1.00 127.59 ? 378  VAL C CA    1 
ATOM   10561 C C     . VAL B 2 378  ? 161.361 363.003 229.852 1.00 127.59 ? 378  VAL C C     1 
ATOM   10562 O O     . VAL B 2 378  ? 161.000 362.148 229.033 1.00 127.59 ? 378  VAL C O     1 
ATOM   10563 C CB    . VAL B 2 378  ? 159.674 363.400 231.711 1.00 127.59 ? 378  VAL C CB    1 
ATOM   10564 C CG1   . VAL B 2 378  ? 159.679 364.921 231.634 1.00 127.59 ? 378  VAL C CG1   1 
ATOM   10565 C CG2   . VAL B 2 378  ? 158.578 362.810 230.830 1.00 127.59 ? 378  VAL C CG2   1 
ATOM   10566 N N     . LEU B 2 379  ? 162.041 364.091 229.479 1.00 124.40 ? 379  LEU C N     1 
ATOM   10567 C CA    . LEU B 2 379  ? 162.339 364.333 228.070 1.00 124.40 ? 379  LEU C CA    1 
ATOM   10568 C C     . LEU B 2 379  ? 163.279 363.277 227.499 1.00 124.40 ? 379  LEU C C     1 
ATOM   10569 O O     . LEU B 2 379  ? 163.350 363.108 226.277 1.00 124.40 ? 379  LEU C O     1 
ATOM   10570 C CB    . LEU B 2 379  ? 162.934 365.731 227.887 1.00 124.40 ? 379  LEU C CB    1 
ATOM   10571 C CG    . LEU B 2 379  ? 164.453 365.898 227.993 1.00 124.40 ? 379  LEU C CG    1 
ATOM   10572 C CD1   . LEU B 2 379  ? 164.867 367.282 227.518 1.00 124.40 ? 379  LEU C CD1   1 
ATOM   10573 C CD2   . LEU B 2 379  ? 164.942 365.655 229.412 1.00 124.40 ? 379  LEU C CD2   1 
ATOM   10574 N N     . LEU B 2 380  ? 164.009 362.563 228.361 1.00 122.14 ? 380  LEU C N     1 
ATOM   10575 C CA    . LEU B 2 380  ? 164.910 361.522 227.879 1.00 122.14 ? 380  LEU C CA    1 
ATOM   10576 C C     . LEU B 2 380  ? 164.146 360.337 227.303 1.00 122.14 ? 380  LEU C C     1 
ATOM   10577 O O     . LEU B 2 380  ? 164.673 359.616 226.448 1.00 122.14 ? 380  LEU C O     1 
ATOM   10578 C CB    . LEU B 2 380  ? 165.831 361.060 229.008 1.00 122.14 ? 380  LEU C CB    1 
ATOM   10579 C CG    . LEU B 2 380  ? 167.198 360.517 228.588 1.00 122.14 ? 380  LEU C CG    1 
ATOM   10580 C CD1   . LEU B 2 380  ? 168.135 361.653 228.205 1.00 122.14 ? 380  LEU C CD1   1 
ATOM   10581 C CD2   . LEU B 2 380  ? 167.804 359.667 229.694 1.00 122.14 ? 380  LEU C CD2   1 
ATOM   10582 N N     . SER B 2 381  ? 162.911 360.114 227.760 1.00 122.57 ? 381  SER C N     1 
ATOM   10583 C CA    . SER B 2 381  ? 162.120 359.000 227.246 1.00 122.57 ? 381  SER C CA    1 
ATOM   10584 C C     . SER B 2 381  ? 161.792 359.188 225.770 1.00 122.57 ? 381  SER C C     1 
ATOM   10585 O O     . SER B 2 381  ? 161.801 358.222 224.997 1.00 122.57 ? 381  SER C O     1 
ATOM   10586 C CB    . SER B 2 381  ? 160.839 358.842 228.065 1.00 122.57 ? 381  SER C CB    1 
ATOM   10587 O OG    . SER B 2 381  ? 160.292 360.104 228.408 1.00 122.57 ? 381  SER C OG    1 
ATOM   10588 N N     . LEU B 2 382  ? 161.492 360.419 225.363 1.00 118.51 ? 382  LEU C N     1 
ATOM   10589 C CA    . LEU B 2 382  ? 161.172 360.688 223.968 1.00 118.51 ? 382  LEU C CA    1 
ATOM   10590 C C     . LEU B 2 382  ? 162.385 360.439 223.080 1.00 118.51 ? 382  LEU C C     1 
ATOM   10591 O O     . LEU B 2 382  ? 163.516 360.788 223.430 1.00 118.51 ? 382  LEU C O     1 
ATOM   10592 C CB    . LEU B 2 382  ? 160.687 362.129 223.804 1.00 118.51 ? 382  LEU C CB    1 
ATOM   10593 C CG    . LEU B 2 382  ? 159.355 362.481 224.470 1.00 118.51 ? 382  LEU C CG    1 
ATOM   10594 C CD1   . LEU B 2 382  ? 159.073 363.971 224.350 1.00 118.51 ? 382  LEU C CD1   1 
ATOM   10595 C CD2   . LEU B 2 382  ? 158.221 361.667 223.867 1.00 118.51 ? 382  LEU C CD2   1 
ATOM   10596 N N     . ALA B 2 383  ? 162.143 359.830 221.924 1.00 104.16 ? 383  ALA C N     1 
ATOM   10597 C CA    . ALA B 2 383  ? 163.211 359.524 220.980 1.00 104.16 ? 383  ALA C CA    1 
ATOM   10598 C C     . ALA B 2 383  ? 162.685 359.508 219.549 1.00 104.16 ? 383  ALA C C     1 
ATOM   10599 O O     . ALA B 2 383  ? 163.372 359.933 218.620 1.00 104.16 ? 383  ALA C O     1 
ATOM   10600 C CB    . ALA B 2 383  ? 163.856 358.190 221.324 1.00 104.16 ? 383  ALA C CB    1 
ATOM   10601 N N     . GLN C 3 23   ? 187.968 386.050 209.699 1.00 147.85 ? 4    GLN D N     1 
ATOM   10602 C CA    . GLN C 3 23   ? 189.262 385.806 209.073 1.00 147.85 ? 4    GLN D CA    1 
ATOM   10603 C C     . GLN C 3 23   ? 190.214 386.972 209.313 1.00 147.85 ? 4    GLN D C     1 
ATOM   10604 O O     . GLN C 3 23   ? 189.789 388.124 209.406 1.00 147.85 ? 4    GLN D O     1 
ATOM   10605 C CB    . GLN C 3 23   ? 189.095 385.562 207.572 1.00 147.85 ? 4    GLN D CB    1 
ATOM   10606 C CG    . GLN C 3 23   ? 188.096 386.490 206.900 1.00 147.85 ? 4    GLN D CG    1 
ATOM   10607 C CD    . GLN C 3 23   ? 187.934 386.198 205.422 1.00 147.85 ? 4    GLN D CD    1 
ATOM   10608 O OE1   . GLN C 3 23   ? 187.179 385.306 205.032 1.00 147.85 ? 4    GLN D OE1   1 
ATOM   10609 N NE2   . GLN C 3 23   ? 188.643 386.950 204.588 1.00 147.85 ? 4    GLN D NE2   1 
ATOM   10610 N N     . LEU C 3 24   ? 191.504 386.666 209.413 1.00 142.28 ? 5    LEU D N     1 
ATOM   10611 C CA    . LEU C 3 24   ? 192.522 387.677 209.650 1.00 142.28 ? 5    LEU D CA    1 
ATOM   10612 C C     . LEU C 3 24   ? 193.020 388.229 208.314 1.00 142.28 ? 5    LEU D C     1 
ATOM   10613 O O     . LEU C 3 24   ? 192.567 387.824 207.239 1.00 142.28 ? 5    LEU D O     1 
ATOM   10614 C CB    . LEU C 3 24   ? 193.659 387.095 210.487 1.00 142.28 ? 5    LEU D CB    1 
ATOM   10615 C CG    . LEU C 3 24   ? 193.338 386.801 211.954 1.00 142.28 ? 5    LEU D CG    1 
ATOM   10616 C CD1   . LEU C 3 24   ? 194.578 386.317 212.688 1.00 142.28 ? 5    LEU D CD1   1 
ATOM   10617 C CD2   . LEU C 3 24   ? 192.753 388.030 212.633 1.00 142.28 ? 5    LEU D CD2   1 
ATOM   10618 N N     . THR C 3 25   ? 193.965 389.164 208.371 1.00 135.25 ? 6    THR D N     1 
ATOM   10619 C CA    . THR C 3 25   ? 194.519 389.775 207.172 1.00 135.25 ? 6    THR D CA    1 
ATOM   10620 C C     . THR C 3 25   ? 196.025 389.917 207.340 1.00 135.25 ? 6    THR D C     1 
ATOM   10621 O O     . THR C 3 25   ? 196.552 389.874 208.454 1.00 135.25 ? 6    THR D O     1 
ATOM   10622 C CB    . THR C 3 25   ? 193.885 391.142 206.883 1.00 135.25 ? 6    THR D CB    1 
ATOM   10623 O OG1   . THR C 3 25   ? 193.709 391.860 208.111 1.00 135.25 ? 6    THR D OG1   1 
ATOM   10624 C CG2   . THR C 3 25   ? 192.536 390.974 206.199 1.00 135.25 ? 6    THR D CG2   1 
ATOM   10625 N N     . GLU C 3 26   ? 196.713 390.081 206.207 1.00 129.91 ? 7    GLU D N     1 
ATOM   10626 C CA    . GLU C 3 26   ? 198.164 390.246 206.239 1.00 129.91 ? 7    GLU D CA    1 
ATOM   10627 C C     . GLU C 3 26   ? 198.559 391.512 206.988 1.00 129.91 ? 7    GLU D C     1 
ATOM   10628 O O     . GLU C 3 26   ? 199.536 391.515 207.748 1.00 129.91 ? 7    GLU D O     1 
ATOM   10629 C CB    . GLU C 3 26   ? 198.721 390.266 204.815 1.00 129.91 ? 7    GLU D CB    1 
ATOM   10630 N N     . GLU C 3 27   ? 197.816 392.603 206.780 1.00 126.55 ? 8    GLU D N     1 
ATOM   10631 C CA    . GLU C 3 27   ? 198.099 393.839 207.501 1.00 126.55 ? 8    GLU D CA    1 
ATOM   10632 C C     . GLU C 3 27   ? 197.908 393.657 209.001 1.00 126.55 ? 8    GLU D C     1 
ATOM   10633 O O     . GLU C 3 27   ? 198.704 394.162 209.802 1.00 126.55 ? 8    GLU D O     1 
ATOM   10634 C CB    . GLU C 3 27   ? 197.209 394.967 206.978 1.00 126.55 ? 8    GLU D CB    1 
ATOM   10635 N N     . GLN C 3 28   ? 196.854 392.940 209.401 1.00 126.10 ? 9    GLN D N     1 
ATOM   10636 C CA    . GLN C 3 28   ? 196.635 392.673 210.819 1.00 126.10 ? 9    GLN D CA    1 
ATOM   10637 C C     . GLN C 3 28   ? 197.764 391.833 211.404 1.00 126.10 ? 9    GLN D C     1 
ATOM   10638 O O     . GLN C 3 28   ? 198.212 392.080 212.529 1.00 126.10 ? 9    GLN D O     1 
ATOM   10639 C CB    . GLN C 3 28   ? 195.288 391.979 211.021 1.00 126.10 ? 9    GLN D CB    1 
ATOM   10640 N N     . ILE C 3 29   ? 198.233 390.832 210.655 1.00 125.33 ? 10   ILE D N     1 
ATOM   10641 C CA    . ILE C 3 29   ? 199.337 389.999 211.127 1.00 125.33 ? 10   ILE D CA    1 
ATOM   10642 C C     . ILE C 3 29   ? 200.603 390.832 211.289 1.00 125.33 ? 10   ILE D C     1 
ATOM   10643 O O     . ILE C 3 29   ? 201.331 390.697 212.281 1.00 125.33 ? 10   ILE D O     1 
ATOM   10644 C CB    . ILE C 3 29   ? 199.555 388.812 210.170 1.00 125.33 ? 10   ILE D CB    1 
ATOM   10645 C CG1   . ILE C 3 29   ? 198.391 387.823 210.272 1.00 125.33 ? 10   ILE D CG1   1 
ATOM   10646 C CG2   . ILE C 3 29   ? 200.874 388.114 210.467 1.00 125.33 ? 10   ILE D CG2   1 
ATOM   10647 C CD1   . ILE C 3 29   ? 198.101 387.364 211.685 1.00 125.33 ? 10   ILE D CD1   1 
ATOM   10648 N N     . ALA C 3 30   ? 200.887 391.703 210.317 1.00 124.57 ? 11   ALA D N     1 
ATOM   10649 C CA    . ALA C 3 30   ? 202.063 392.562 210.414 1.00 124.57 ? 11   ALA D CA    1 
ATOM   10650 C C     . ALA C 3 30   ? 201.959 393.511 211.601 1.00 124.57 ? 11   ALA D C     1 
ATOM   10651 O O     . ALA C 3 30   ? 202.944 393.737 212.314 1.00 124.57 ? 11   ALA D O     1 
ATOM   10652 C CB    . ALA C 3 30   ? 202.250 393.345 209.114 1.00 124.57 ? 11   ALA D CB    1 
ATOM   10653 N N     . GLU C 3 31   ? 200.771 394.079 211.828 1.00 123.03 ? 12   GLU D N     1 
ATOM   10654 C CA    . GLU C 3 31   ? 200.578 394.966 212.970 1.00 123.03 ? 12   GLU D CA    1 
ATOM   10655 C C     . GLU C 3 31   ? 200.764 394.222 214.286 1.00 123.03 ? 12   GLU D C     1 
ATOM   10656 O O     . GLU C 3 31   ? 201.369 394.750 215.226 1.00 123.03 ? 12   GLU D O     1 
ATOM   10657 C CB    . GLU C 3 31   ? 199.193 395.607 212.907 1.00 123.03 ? 12   GLU D CB    1 
ATOM   10658 N N     . PHE C 3 32   ? 200.246 392.995 214.373 1.00 123.46 ? 13   PHE D N     1 
ATOM   10659 C CA    . PHE C 3 32   ? 200.420 392.201 215.586 1.00 123.46 ? 13   PHE D CA    1 
ATOM   10660 C C     . PHE C 3 32   ? 201.888 391.868 215.820 1.00 123.46 ? 13   PHE D C     1 
ATOM   10661 O O     . PHE C 3 32   ? 202.368 391.911 216.959 1.00 123.46 ? 13   PHE D O     1 
ATOM   10662 C CB    . PHE C 3 32   ? 199.585 390.924 215.501 1.00 123.46 ? 13   PHE D CB    1 
ATOM   10663 N N     . LYS C 3 33   ? 202.616 391.527 214.754 1.00 125.42 ? 14   LYS D N     1 
ATOM   10664 C CA    . LYS C 3 33   ? 204.042 391.249 214.891 1.00 125.42 ? 14   LYS D CA    1 
ATOM   10665 C C     . LYS C 3 33   ? 204.804 392.487 215.348 1.00 125.42 ? 14   LYS D C     1 
ATOM   10666 O O     . LYS C 3 33   ? 205.694 392.400 216.203 1.00 125.42 ? 14   LYS D O     1 
ATOM   10667 C CB    . LYS C 3 33   ? 204.605 390.728 213.569 1.00 125.42 ? 14   LYS D CB    1 
ATOM   10668 N N     . GLU C 3 34   ? 204.466 393.652 214.788 1.00 124.84 ? 15   GLU D N     1 
ATOM   10669 C CA    . GLU C 3 34   ? 205.112 394.892 215.209 1.00 124.84 ? 15   GLU D CA    1 
ATOM   10670 C C     . GLU C 3 34   ? 204.809 395.201 216.670 1.00 124.84 ? 15   GLU D C     1 
ATOM   10671 O O     . GLU C 3 34   ? 205.693 395.636 217.417 1.00 124.84 ? 15   GLU D O     1 
ATOM   10672 C CB    . GLU C 3 34   ? 204.668 396.046 214.312 1.00 124.84 ? 15   GLU D CB    1 
ATOM   10673 N N     . ALA C 3 35   ? 203.561 394.986 217.094 1.00 125.56 ? 16   ALA D N     1 
ATOM   10674 C CA    . ALA C 3 35   ? 203.200 395.209 218.490 1.00 125.56 ? 16   ALA D CA    1 
ATOM   10675 C C     . ALA C 3 35   ? 203.962 394.270 219.415 1.00 125.56 ? 16   ALA D C     1 
ATOM   10676 O O     . ALA C 3 35   ? 204.438 394.685 220.478 1.00 125.56 ? 16   ALA D O     1 
ATOM   10677 C CB    . ALA C 3 35   ? 201.692 395.037 218.676 1.00 125.56 ? 16   ALA D CB    1 
ATOM   10678 N N     . PHE C 3 36   ? 204.084 392.998 219.028 1.00 126.34 ? 17   PHE D N     1 
ATOM   10679 C CA    . PHE C 3 36   ? 204.835 392.046 219.839 1.00 126.34 ? 17   PHE D CA    1 
ATOM   10680 C C     . PHE C 3 36   ? 206.305 392.436 219.929 1.00 126.34 ? 17   PHE D C     1 
ATOM   10681 O O     . PHE C 3 36   ? 206.919 392.330 220.998 1.00 126.34 ? 17   PHE D O     1 
ATOM   10682 C CB    . PHE C 3 36   ? 204.687 390.636 219.266 1.00 126.34 ? 17   PHE D CB    1 
ATOM   10683 N N     . SER C 3 37   ? 206.889 392.883 218.815 1.00 127.13 ? 18   SER D N     1 
ATOM   10684 C CA    . SER C 3 37   ? 208.287 393.304 218.830 1.00 127.13 ? 18   SER D CA    1 
ATOM   10685 C C     . SER C 3 37   ? 208.486 394.537 219.705 1.00 127.13 ? 18   SER D C     1 
ATOM   10686 O O     . SER C 3 37   ? 209.469 394.626 220.450 1.00 127.13 ? 18   SER D O     1 
ATOM   10687 C CB    . SER C 3 37   ? 208.769 393.574 217.405 1.00 127.13 ? 18   SER D CB    1 
ATOM   10688 O OG    . SER C 3 37   ? 208.008 394.600 216.794 1.00 127.13 ? 18   SER D OG    1 
ATOM   10689 N N     . LEU C 3 38   ? 207.564 395.499 219.629 1.00 127.89 ? 19   LEU D N     1 
ATOM   10690 C CA    . LEU C 3 38   ? 207.700 396.730 220.399 1.00 127.89 ? 19   LEU D CA    1 
ATOM   10691 C C     . LEU C 3 38   ? 207.346 396.540 221.869 1.00 127.89 ? 19   LEU D C     1 
ATOM   10692 O O     . LEU C 3 38   ? 207.734 397.371 222.698 1.00 127.89 ? 19   LEU D O     1 
ATOM   10693 C CB    . LEU C 3 38   ? 206.824 397.826 219.786 1.00 127.89 ? 19   LEU D CB    1 
ATOM   10694 C CG    . LEU C 3 38   ? 207.066 399.267 220.241 1.00 127.89 ? 19   LEU D CG    1 
ATOM   10695 C CD1   . LEU C 3 38   ? 208.422 399.763 219.763 1.00 127.89 ? 19   LEU D CD1   1 
ATOM   10696 C CD2   . LEU C 3 38   ? 205.953 400.180 219.750 1.00 127.89 ? 19   LEU D CD2   1 
ATOM   10697 N N     . PHE C 3 39   ? 206.623 395.470 222.210 1.00 128.87 ? 20   PHE D N     1 
ATOM   10698 C CA    . PHE C 3 39   ? 206.226 395.255 223.599 1.00 128.87 ? 20   PHE D CA    1 
ATOM   10699 C C     . PHE C 3 39   ? 207.437 395.052 224.501 1.00 128.87 ? 20   PHE D C     1 
ATOM   10700 O O     . PHE C 3 39   ? 207.479 395.574 225.621 1.00 128.87 ? 20   PHE D O     1 
ATOM   10701 C CB    . PHE C 3 39   ? 205.279 394.059 223.693 1.00 128.87 ? 20   PHE D CB    1 
ATOM   10702 N N     . ASP C 3 40   ? 208.428 394.300 224.034 1.00 135.20 ? 21   ASP D N     1 
ATOM   10703 C CA    . ASP C 3 40   ? 209.628 394.012 224.805 1.00 135.20 ? 21   ASP D CA    1 
ATOM   10704 C C     . ASP C 3 40   ? 210.799 394.835 224.284 1.00 135.20 ? 21   ASP D C     1 
ATOM   10705 O O     . ASP C 3 40   ? 210.970 394.993 223.070 1.00 135.20 ? 21   ASP D O     1 
ATOM   10706 C CB    . ASP C 3 40   ? 209.967 392.518 224.760 1.00 135.20 ? 21   ASP D CB    1 
ATOM   10707 C CG    . ASP C 3 40   ? 209.723 391.901 223.394 1.00 135.20 ? 21   ASP D CG    1 
ATOM   10708 O OD1   . ASP C 3 40   ? 210.249 392.428 222.391 1.00 135.20 ? 21   ASP D OD1   1 
ATOM   10709 O OD2   . ASP C 3 40   ? 209.001 390.885 223.323 1.00 135.20 ? 21   ASP D OD2   1 
ATOM   10710 N N     . LYS C 3 41   ? 211.594 395.373 225.212 1.00 139.79 ? 22   LYS D N     1 
ATOM   10711 C CA    . LYS C 3 41   ? 212.761 396.158 224.824 1.00 139.79 ? 22   LYS D CA    1 
ATOM   10712 C C     . LYS C 3 41   ? 213.794 395.296 224.108 1.00 139.79 ? 22   LYS D C     1 
ATOM   10713 O O     . LYS C 3 41   ? 214.405 395.732 223.125 1.00 139.79 ? 22   LYS D O     1 
ATOM   10714 C CB    . LYS C 3 41   ? 213.377 396.826 226.053 1.00 139.79 ? 22   LYS D CB    1 
ATOM   10715 C CG    . LYS C 3 41   ? 212.452 397.808 226.754 1.00 139.79 ? 22   LYS D CG    1 
ATOM   10716 C CD    . LYS C 3 41   ? 213.206 398.653 227.768 1.00 139.79 ? 22   LYS D CD    1 
ATOM   10717 C CE    . LYS C 3 41   ? 213.870 397.786 228.825 1.00 139.79 ? 22   LYS D CE    1 
ATOM   10718 N NZ    . LYS C 3 41   ? 212.894 396.884 229.496 1.00 139.79 ? 22   LYS D NZ    1 
ATOM   10719 N N     . ASP C 3 42   ? 214.002 394.072 224.585 1.00 142.40 ? 23   ASP D N     1 
ATOM   10720 C CA    . ASP C 3 42   ? 214.960 393.147 223.999 1.00 142.40 ? 23   ASP D CA    1 
ATOM   10721 C C     . ASP C 3 42   ? 214.223 391.997 223.326 1.00 142.40 ? 23   ASP D C     1 
ATOM   10722 O O     . ASP C 3 42   ? 213.187 391.538 223.817 1.00 142.40 ? 23   ASP D O     1 
ATOM   10723 C CB    . ASP C 3 42   ? 215.927 392.610 225.060 1.00 142.40 ? 23   ASP D CB    1 
ATOM   10724 C CG    . ASP C 3 42   ? 215.210 392.016 226.259 1.00 142.40 ? 23   ASP D CG    1 
ATOM   10725 O OD1   . ASP C 3 42   ? 214.652 390.906 226.136 1.00 142.40 ? 23   ASP D OD1   1 
ATOM   10726 O OD2   . ASP C 3 42   ? 215.206 392.663 227.328 1.00 142.40 ? 23   ASP D OD2   1 
ATOM   10727 N N     . GLY C 3 43   ? 214.759 391.540 222.197 1.00 140.42 ? 24   GLY D N     1 
ATOM   10728 C CA    . GLY C 3 43   ? 214.128 390.478 221.440 1.00 140.42 ? 24   GLY D CA    1 
ATOM   10729 C C     . GLY C 3 43   ? 214.449 389.091 221.956 1.00 140.42 ? 24   GLY D C     1 
ATOM   10730 O O     . GLY C 3 43   ? 215.553 388.581 221.748 1.00 140.42 ? 24   GLY D O     1 
ATOM   10731 N N     . ASP C 3 44   ? 213.483 388.470 222.634 1.00 138.43 ? 25   ASP D N     1 
ATOM   10732 C CA    . ASP C 3 44   ? 213.654 387.114 223.135 1.00 138.43 ? 25   ASP D CA    1 
ATOM   10733 C C     . ASP C 3 44   ? 212.416 386.244 222.963 1.00 138.43 ? 25   ASP D C     1 
ATOM   10734 O O     . ASP C 3 44   ? 212.416 385.107 223.444 1.00 138.43 ? 25   ASP D O     1 
ATOM   10735 C CB    . ASP C 3 44   ? 214.059 387.137 224.619 1.00 138.43 ? 25   ASP D CB    1 
ATOM   10736 C CG    . ASP C 3 44   ? 212.926 387.572 225.528 1.00 138.43 ? 25   ASP D CG    1 
ATOM   10737 O OD1   . ASP C 3 44   ? 212.079 388.376 225.084 1.00 138.43 ? 25   ASP D OD1   1 
ATOM   10738 O OD2   . ASP C 3 44   ? 212.881 387.110 226.688 1.00 138.43 ? 25   ASP D OD2   1 
ATOM   10739 N N     . GLY C 3 45   ? 211.370 386.734 222.301 1.00 132.61 ? 26   GLY D N     1 
ATOM   10740 C CA    . GLY C 3 45   ? 210.154 385.976 222.109 1.00 132.61 ? 26   GLY D CA    1 
ATOM   10741 C C     . GLY C 3 45   ? 209.158 386.056 223.244 1.00 132.61 ? 26   GLY D C     1 
ATOM   10742 O O     . GLY C 3 45   ? 208.067 385.482 223.129 1.00 132.61 ? 26   GLY D O     1 
ATOM   10743 N N     . THR C 3 46   ? 209.490 386.747 224.332 1.00 134.18 ? 27   THR D N     1 
ATOM   10744 C CA    . THR C 3 46   ? 208.608 386.873 225.482 1.00 134.18 ? 27   THR D CA    1 
ATOM   10745 C C     . THR C 3 46   ? 208.466 388.341 225.856 1.00 134.18 ? 27   THR D C     1 
ATOM   10746 O O     . THR C 3 46   ? 209.437 389.102 225.833 1.00 134.18 ? 27   THR D O     1 
ATOM   10747 C CB    . THR C 3 46   ? 209.136 386.075 226.686 1.00 134.18 ? 27   THR D CB    1 
ATOM   10748 O OG1   . THR C 3 46   ? 209.453 384.739 226.274 1.00 134.18 ? 27   THR D OG1   1 
ATOM   10749 C CG2   . THR C 3 46   ? 208.094 386.020 227.794 1.00 134.18 ? 27   THR D CG2   1 
ATOM   10750 N N     . ILE C 3 47   ? 207.236 388.734 226.196 1.00 135.11 ? 28   ILE D N     1 
ATOM   10751 C CA    . ILE C 3 47   ? 206.987 390.109 226.617 1.00 135.11 ? 28   ILE D CA    1 
ATOM   10752 C C     . ILE C 3 47   ? 207.707 390.405 227.927 1.00 135.11 ? 28   ILE D C     1 
ATOM   10753 O O     . ILE C 3 47   ? 208.145 391.538 228.163 1.00 135.11 ? 28   ILE D O     1 
ATOM   10754 C CB    . ILE C 3 47   ? 205.474 390.369 226.728 1.00 135.11 ? 28   ILE D CB    1 
ATOM   10755 C CG1   . ILE C 3 47   ? 204.736 389.746 225.541 1.00 135.11 ? 28   ILE D CG1   1 
ATOM   10756 C CG2   . ILE C 3 47   ? 205.192 391.862 226.809 1.00 135.11 ? 28   ILE D CG2   1 
ATOM   10757 C CD1   . ILE C 3 47   ? 205.082 390.372 224.207 1.00 135.11 ? 28   ILE D CD1   1 
ATOM   10758 N N     . THR C 3 48   ? 207.806 389.402 228.807 1.00 133.49 ? 29   THR D N     1 
ATOM   10759 C CA    . THR C 3 48   ? 208.555 389.456 230.062 1.00 133.49 ? 29   THR D CA    1 
ATOM   10760 C C     . THR C 3 48   ? 207.850 390.323 231.099 1.00 133.49 ? 29   THR D C     1 
ATOM   10761 O O     . THR C 3 48   ? 207.338 391.401 230.779 1.00 133.49 ? 29   THR D O     1 
ATOM   10762 C CB    . THR C 3 48   ? 209.990 389.950 229.836 1.00 133.49 ? 29   THR D CB    1 
ATOM   10763 O OG1   . THR C 3 48   ? 210.554 389.283 228.700 1.00 133.49 ? 29   THR D OG1   1 
ATOM   10764 C CG2   . THR C 3 48   ? 210.852 389.670 231.058 1.00 133.49 ? 29   THR D CG2   1 
ATOM   10765 N N     . THR C 3 49   ? 207.815 389.851 232.348 1.00 134.28 ? 30   THR D N     1 
ATOM   10766 C CA    . THR C 3 49   ? 207.150 390.601 233.409 1.00 134.28 ? 30   THR D CA    1 
ATOM   10767 C C     . THR C 3 49   ? 207.854 391.925 233.683 1.00 134.28 ? 30   THR D C     1 
ATOM   10768 O O     . THR C 3 49   ? 207.199 392.950 233.903 1.00 134.28 ? 30   THR D O     1 
ATOM   10769 C CB    . THR C 3 49   ? 207.082 389.760 234.685 1.00 134.28 ? 30   THR D CB    1 
ATOM   10770 O OG1   . THR C 3 49   ? 208.407 389.393 235.089 1.00 134.28 ? 30   THR D OG1   1 
ATOM   10771 C CG2   . THR C 3 49   ? 206.262 388.500 234.448 1.00 134.28 ? 30   THR D CG2   1 
ATOM   10772 N N     . LYS C 3 50   ? 209.190 391.920 233.684 1.00 132.26 ? 31   LYS D N     1 
ATOM   10773 C CA    . LYS C 3 50   ? 209.933 393.147 233.956 1.00 132.26 ? 31   LYS D CA    1 
ATOM   10774 C C     . LYS C 3 50   ? 209.695 394.193 232.874 1.00 132.26 ? 31   LYS D C     1 
ATOM   10775 O O     . LYS C 3 50   ? 209.484 395.374 233.176 1.00 132.26 ? 31   LYS D O     1 
ATOM   10776 C CB    . LYS C 3 50   ? 211.425 392.839 234.086 1.00 132.26 ? 31   LYS D CB    1 
ATOM   10777 N N     . GLU C 3 51   ? 209.728 393.779 231.604 1.00 131.10 ? 32   GLU D N     1 
ATOM   10778 C CA    . GLU C 3 51   ? 209.487 394.721 230.516 1.00 131.10 ? 32   GLU D CA    1 
ATOM   10779 C C     . GLU C 3 51   ? 208.061 395.254 230.555 1.00 131.10 ? 32   GLU D C     1 
ATOM   10780 O O     . GLU C 3 51   ? 207.828 396.444 230.308 1.00 131.10 ? 32   GLU D O     1 
ATOM   10781 C CB    . GLU C 3 51   ? 209.779 394.057 229.171 1.00 131.10 ? 32   GLU D CB    1 
ATOM   10782 N N     . LEU C 3 52   ? 207.092 394.388 230.863 1.00 134.09 ? 33   LEU D N     1 
ATOM   10783 C CA    . LEU C 3 52   ? 205.709 394.838 230.985 1.00 134.09 ? 33   LEU D CA    1 
ATOM   10784 C C     . LEU C 3 52   ? 205.557 395.845 232.118 1.00 134.09 ? 33   LEU D C     1 
ATOM   10785 O O     . LEU C 3 52   ? 204.854 396.852 231.974 1.00 134.09 ? 33   LEU D O     1 
ATOM   10786 C CB    . LEU C 3 52   ? 204.785 393.639 231.203 1.00 134.09 ? 33   LEU D CB    1 
ATOM   10787 C CG    . LEU C 3 52   ? 203.280 393.913 231.190 1.00 134.09 ? 33   LEU D CG    1 
ATOM   10788 C CD1   . LEU C 3 52   ? 202.902 394.807 230.018 1.00 134.09 ? 33   LEU D CD1   1 
ATOM   10789 C CD2   . LEU C 3 52   ? 202.497 392.610 231.149 1.00 134.09 ? 33   LEU D CD2   1 
ATOM   10790 N N     . GLY C 3 53   ? 206.210 395.590 233.253 1.00 130.48 ? 34   GLY D N     1 
ATOM   10791 C CA    . GLY C 3 53   ? 206.161 396.540 234.352 1.00 130.48 ? 34   GLY D CA    1 
ATOM   10792 C C     . GLY C 3 53   ? 206.794 397.873 234.001 1.00 130.48 ? 34   GLY D C     1 
ATOM   10793 O O     . GLY C 3 53   ? 206.267 398.931 234.352 1.00 130.48 ? 34   GLY D O     1 
ATOM   10794 N N     . THR C 3 54   ? 207.933 397.840 233.305 1.00 133.08 ? 35   THR D N     1 
ATOM   10795 C CA    . THR C 3 54   ? 208.571 399.084 232.881 1.00 133.08 ? 35   THR D CA    1 
ATOM   10796 C C     . THR C 3 54   ? 207.682 399.856 231.913 1.00 133.08 ? 35   THR D C     1 
ATOM   10797 O O     . THR C 3 54   ? 207.584 401.086 231.995 1.00 133.08 ? 35   THR D O     1 
ATOM   10798 C CB    . THR C 3 54   ? 209.932 398.800 232.245 1.00 133.08 ? 35   THR D CB    1 
ATOM   10799 O OG1   . THR C 3 54   ? 209.777 397.862 231.174 1.00 133.08 ? 35   THR D OG1   1 
ATOM   10800 C CG2   . THR C 3 54   ? 210.900 398.241 233.278 1.00 133.08 ? 35   THR D CG2   1 
ATOM   10801 N N     . VAL C 3 55   ? 207.025 399.149 230.989 1.00 132.75 ? 36   VAL D N     1 
ATOM   10802 C CA    . VAL C 3 55   ? 206.107 399.804 230.061 1.00 132.75 ? 36   VAL D CA    1 
ATOM   10803 C C     . VAL C 3 55   ? 204.943 400.433 230.819 1.00 132.75 ? 36   VAL D C     1 
ATOM   10804 O O     . VAL C 3 55   ? 204.527 401.562 230.525 1.00 132.75 ? 36   VAL D O     1 
ATOM   10805 C CB    . VAL C 3 55   ? 205.620 398.802 228.997 1.00 132.75 ? 36   VAL D CB    1 
ATOM   10806 C CG1   . VAL C 3 55   ? 204.389 399.335 228.278 1.00 132.75 ? 36   VAL D CG1   1 
ATOM   10807 C CG2   . VAL C 3 55   ? 206.732 398.501 228.005 1.00 132.75 ? 36   VAL D CG2   1 
ATOM   10808 N N     . MET C 3 56   ? 204.401 399.715 231.806 1.00 133.01 ? 37   MET D N     1 
ATOM   10809 C CA    . MET C 3 56   ? 203.299 400.254 232.597 1.00 133.01 ? 37   MET D CA    1 
ATOM   10810 C C     . MET C 3 56   ? 203.724 401.501 233.364 1.00 133.01 ? 37   MET D C     1 
ATOM   10811 O O     . MET C 3 56   ? 202.974 402.482 233.432 1.00 133.01 ? 37   MET D O     1 
ATOM   10812 C CB    . MET C 3 56   ? 202.771 399.187 233.556 1.00 133.01 ? 37   MET D CB    1 
ATOM   10813 N N     . ARG C 3 57   ? 204.922 401.480 233.955 1.00 132.50 ? 38   ARG D N     1 
ATOM   10814 C CA    . ARG C 3 57   ? 205.413 402.657 234.667 1.00 132.50 ? 38   ARG D CA    1 
ATOM   10815 C C     . ARG C 3 57   ? 205.638 403.826 233.715 1.00 132.50 ? 38   ARG D C     1 
ATOM   10816 O O     . ARG C 3 57   ? 205.353 404.979 234.058 1.00 132.50 ? 38   ARG D O     1 
ATOM   10817 C CB    . ARG C 3 57   ? 206.700 402.326 235.424 1.00 132.50 ? 38   ARG D CB    1 
ATOM   10818 C CG    . ARG C 3 57   ? 206.559 401.200 236.435 1.00 132.50 ? 38   ARG D CG    1 
ATOM   10819 C CD    . ARG C 3 57   ? 206.185 401.727 237.810 1.00 132.50 ? 38   ARG D CD    1 
ATOM   10820 N NE    . ARG C 3 57   ? 205.731 400.661 238.695 1.00 132.50 ? 38   ARG D NE    1 
ATOM   10821 C CZ    . ARG C 3 57   ? 205.600 400.782 240.009 1.00 132.50 ? 38   ARG D CZ    1 
ATOM   10822 N NH1   . ARG C 3 57   ? 205.881 401.916 240.630 1.00 132.50 ? 38   ARG D NH1   1 
ATOM   10823 N NH2   . ARG C 3 57   ? 205.176 399.739 240.717 1.00 132.50 ? 38   ARG D NH2   1 
ATOM   10824 N N     . SER C 3 58   ? 206.158 403.549 232.516 1.00 133.85 ? 39   SER D N     1 
ATOM   10825 C CA    . SER C 3 58   ? 206.356 404.608 231.531 1.00 133.85 ? 39   SER D CA    1 
ATOM   10826 C C     . SER C 3 58   ? 205.028 405.221 231.106 1.00 133.85 ? 39   SER D C     1 
ATOM   10827 O O     . SER C 3 58   ? 204.926 406.441 230.931 1.00 133.85 ? 39   SER D O     1 
ATOM   10828 C CB    . SER C 3 58   ? 207.109 404.062 230.318 1.00 133.85 ? 39   SER D CB    1 
ATOM   10829 O OG    . SER C 3 58   ? 206.947 404.909 229.194 1.00 133.85 ? 39   SER D OG    1 
ATOM   10830 N N     . LEU C 3 59   ? 203.999 404.388 230.929 1.00 135.35 ? 40   LEU D N     1 
ATOM   10831 C CA    . LEU C 3 59   ? 202.685 404.903 230.555 1.00 135.35 ? 40   LEU D CA    1 
ATOM   10832 C C     . LEU C 3 59   ? 202.089 405.772 231.655 1.00 135.35 ? 40   LEU D C     1 
ATOM   10833 O O     . LEU C 3 59   ? 201.350 406.720 231.365 1.00 135.35 ? 40   LEU D O     1 
ATOM   10834 C CB    . LEU C 3 59   ? 201.745 403.744 230.221 1.00 135.35 ? 40   LEU D CB    1 
ATOM   10835 C CG    . LEU C 3 59   ? 200.371 404.106 229.651 1.00 135.35 ? 40   LEU D CG    1 
ATOM   10836 C CD1   . LEU C 3 59   ? 200.501 405.130 228.533 1.00 135.35 ? 40   LEU D CD1   1 
ATOM   10837 C CD2   . LEU C 3 59   ? 199.648 402.860 229.161 1.00 135.35 ? 40   LEU D CD2   1 
ATOM   10838 N N     . GLY C 3 60   ? 202.396 405.471 232.914 1.00 131.48 ? 41   GLY D N     1 
ATOM   10839 C CA    . GLY C 3 60   ? 201.876 406.242 234.026 1.00 131.48 ? 41   GLY D CA    1 
ATOM   10840 C C     . GLY C 3 60   ? 201.041 405.415 234.980 1.00 131.48 ? 41   GLY D C     1 
ATOM   10841 O O     . GLY C 3 60   ? 200.179 405.947 235.686 1.00 131.48 ? 41   GLY D O     1 
ATOM   10842 N N     . GLN C 3 61   ? 201.290 404.107 235.010 1.00 134.79 ? 42   GLN D N     1 
ATOM   10843 C CA    . GLN C 3 61   ? 200.559 403.186 235.866 1.00 134.79 ? 42   GLN D CA    1 
ATOM   10844 C C     . GLN C 3 61   ? 201.539 402.409 236.732 1.00 134.79 ? 42   GLN D C     1 
ATOM   10845 O O     . GLN C 3 61   ? 202.665 402.123 236.318 1.00 134.79 ? 42   GLN D O     1 
ATOM   10846 C CB    . GLN C 3 61   ? 199.704 402.210 235.043 1.00 134.79 ? 42   GLN D CB    1 
ATOM   10847 C CG    . GLN C 3 61   ? 199.190 402.782 233.731 1.00 134.79 ? 42   GLN D CG    1 
ATOM   10848 C CD    . GLN C 3 61   ? 198.238 403.944 233.934 1.00 134.79 ? 42   GLN D CD    1 
ATOM   10849 O OE1   . GLN C 3 61   ? 197.402 403.926 234.838 1.00 134.79 ? 42   GLN D OE1   1 
ATOM   10850 N NE2   . GLN C 3 61   ? 198.360 404.963 233.092 1.00 134.79 ? 42   GLN D NE2   1 
ATOM   10851 N N     . ASN C 3 62   ? 201.099 402.069 237.941 1.00 127.91 ? 43   ASN D N     1 
ATOM   10852 C CA    . ASN C 3 62   ? 201.910 401.323 238.903 1.00 127.91 ? 43   ASN D CA    1 
ATOM   10853 C C     . ASN C 3 62   ? 201.115 400.129 239.416 1.00 127.91 ? 43   ASN D C     1 
ATOM   10854 O O     . ASN C 3 62   ? 200.633 400.129 240.555 1.00 127.91 ? 43   ASN D O     1 
ATOM   10855 C CB    . ASN C 3 62   ? 202.356 402.223 240.056 1.00 127.91 ? 43   ASN D CB    1 
ATOM   10856 N N     . PRO C 3 63   ? 200.951 399.093 238.593 1.00 127.91 ? 44   PRO D N     1 
ATOM   10857 C CA    . PRO C 3 63   ? 200.229 397.901 239.050 1.00 127.91 ? 44   PRO D CA    1 
ATOM   10858 C C     . PRO C 3 63   ? 200.982 397.188 240.163 1.00 127.91 ? 44   PRO D C     1 
ATOM   10859 O O     . PRO C 3 63   ? 202.214 397.208 240.224 1.00 127.91 ? 44   PRO D O     1 
ATOM   10860 C CB    . PRO C 3 63   ? 200.139 397.029 237.790 1.00 127.91 ? 44   PRO D CB    1 
ATOM   10861 C CG    . PRO C 3 63   ? 200.439 397.953 236.646 1.00 127.91 ? 44   PRO D CG    1 
ATOM   10862 C CD    . PRO C 3 63   ? 201.391 398.964 237.194 1.00 127.91 ? 44   PRO D CD    1 
ATOM   10863 N N     . THR C 3 64   ? 200.223 396.554 241.051 1.00 127.79 ? 45   THR D N     1 
ATOM   10864 C CA    . THR C 3 64   ? 200.820 395.794 242.137 1.00 127.79 ? 45   THR D CA    1 
ATOM   10865 C C     . THR C 3 64   ? 201.457 394.512 241.608 1.00 127.79 ? 45   THR D C     1 
ATOM   10866 O O     . THR C 3 64   ? 201.100 393.999 240.543 1.00 127.79 ? 45   THR D O     1 
ATOM   10867 C CB    . THR C 3 64   ? 199.773 395.457 243.200 1.00 127.79 ? 45   THR D CB    1 
ATOM   10868 N N     . GLU C 3 65   ? 202.426 393.999 242.370 1.00 131.48 ? 46   GLU D N     1 
ATOM   10869 C CA    . GLU C 3 65   ? 203.091 392.758 241.983 1.00 131.48 ? 46   GLU D CA    1 
ATOM   10870 C C     . GLU C 3 65   ? 202.113 391.590 241.967 1.00 131.48 ? 46   GLU D C     1 
ATOM   10871 O O     . GLU C 3 65   ? 202.143 390.758 241.051 1.00 131.48 ? 46   GLU D O     1 
ATOM   10872 C CB    . GLU C 3 65   ? 204.257 392.470 242.930 1.00 131.48 ? 46   GLU D CB    1 
ATOM   10873 N N     . ALA C 3 66   ? 201.240 391.509 242.974 1.00 135.74 ? 47   ALA D N     1 
ATOM   10874 C CA    . ALA C 3 66   ? 200.239 390.448 243.004 1.00 135.74 ? 47   ALA D CA    1 
ATOM   10875 C C     . ALA C 3 66   ? 199.276 390.566 241.829 1.00 135.74 ? 47   ALA D C     1 
ATOM   10876 O O     . ALA C 3 66   ? 198.906 389.558 241.217 1.00 135.74 ? 47   ALA D O     1 
ATOM   10877 C CB    . ALA C 3 66   ? 199.479 390.479 244.329 1.00 135.74 ? 47   ALA D CB    1 
ATOM   10878 N N     . GLU C 3 67   ? 198.857 391.792 241.503 1.00 137.90 ? 48   GLU D N     1 
ATOM   10879 C CA    . GLU C 3 67   ? 197.968 391.992 240.362 1.00 137.90 ? 48   GLU D CA    1 
ATOM   10880 C C     . GLU C 3 67   ? 198.643 391.586 239.058 1.00 137.90 ? 48   GLU D C     1 
ATOM   10881 O O     . GLU C 3 67   ? 198.019 390.954 238.198 1.00 137.90 ? 48   GLU D O     1 
ATOM   10882 C CB    . GLU C 3 67   ? 197.512 393.449 240.302 1.00 137.90 ? 48   GLU D CB    1 
ATOM   10883 N N     . LEU C 3 68   ? 199.919 391.944 238.892 1.00 139.95 ? 49   LEU D N     1 
ATOM   10884 C CA    . LEU C 3 68   ? 200.644 391.560 237.685 1.00 139.95 ? 49   LEU D CA    1 
ATOM   10885 C C     . LEU C 3 68   ? 200.793 390.046 237.589 1.00 139.95 ? 49   LEU D C     1 
ATOM   10886 O O     . LEU C 3 68   ? 200.645 389.468 236.506 1.00 139.95 ? 49   LEU D O     1 
ATOM   10887 C CB    . LEU C 3 68   ? 202.014 392.238 237.658 1.00 139.95 ? 49   LEU D CB    1 
ATOM   10888 N N     . GLN C 3 69   ? 201.091 389.388 238.713 1.00 143.19 ? 50   GLN D N     1 
ATOM   10889 C CA    . GLN C 3 69   ? 201.201 387.933 238.710 1.00 143.19 ? 50   GLN D CA    1 
ATOM   10890 C C     . GLN C 3 69   ? 199.868 387.281 238.364 1.00 143.19 ? 50   GLN D C     1 
ATOM   10891 O O     . GLN C 3 69   ? 199.822 386.310 237.598 1.00 143.19 ? 50   GLN D O     1 
ATOM   10892 C CB    . GLN C 3 69   ? 201.707 387.444 240.068 1.00 143.19 ? 50   GLN D CB    1 
ATOM   10893 C CG    . GLN C 3 69   ? 201.229 386.052 240.462 1.00 143.19 ? 50   GLN D CG    1 
ATOM   10894 C CD    . GLN C 3 69   ? 202.079 384.944 239.868 1.00 143.19 ? 50   GLN D CD    1 
ATOM   10895 O OE1   . GLN C 3 69   ? 202.654 385.093 238.789 1.00 143.19 ? 50   GLN D OE1   1 
ATOM   10896 N NE2   . GLN C 3 69   ? 202.163 383.822 240.573 1.00 143.19 ? 50   GLN D NE2   1 
ATOM   10897 N N     . ASP C 3 70   ? 198.770 387.803 238.917 1.00 146.40 ? 51   ASP D N     1 
ATOM   10898 C CA    . ASP C 3 70   ? 197.451 387.266 238.600 1.00 146.40 ? 51   ASP D CA    1 
ATOM   10899 C C     . ASP C 3 70   ? 197.120 387.455 237.125 1.00 146.40 ? 51   ASP D C     1 
ATOM   10900 O O     . ASP C 3 70   ? 196.567 386.553 236.485 1.00 146.40 ? 51   ASP D O     1 
ATOM   10901 C CB    . ASP C 3 70   ? 196.391 387.930 239.480 1.00 146.40 ? 51   ASP D CB    1 
ATOM   10902 C CG    . ASP C 3 70   ? 194.981 387.707 238.966 1.00 146.40 ? 51   ASP D CG    1 
ATOM   10903 O OD1   . ASP C 3 70   ? 194.636 386.549 238.648 1.00 146.40 ? 51   ASP D OD1   1 
ATOM   10904 O OD2   . ASP C 3 70   ? 194.217 388.691 238.881 1.00 146.40 ? 51   ASP D OD2   1 
ATOM   10905 N N     . MET C 3 71   ? 197.450 388.623 236.568 1.00 144.13 ? 52   MET D N     1 
ATOM   10906 C CA    . MET C 3 71   ? 197.212 388.862 235.148 1.00 144.13 ? 52   MET D CA    1 
ATOM   10907 C C     . MET C 3 71   ? 198.026 387.908 234.285 1.00 144.13 ? 52   MET D C     1 
ATOM   10908 O O     . MET C 3 71   ? 197.517 387.363 233.298 1.00 144.13 ? 52   MET D O     1 
ATOM   10909 C CB    . MET C 3 71   ? 197.541 390.312 234.797 1.00 144.13 ? 52   MET D CB    1 
ATOM   10910 N N     . ILE C 3 72   ? 199.294 387.692 234.643 1.00 145.58 ? 53   ILE D N     1 
ATOM   10911 C CA    . ILE C 3 72   ? 200.141 386.778 233.882 1.00 145.58 ? 53   ILE D CA    1 
ATOM   10912 C C     . ILE C 3 72   ? 199.584 385.362 233.943 1.00 145.58 ? 53   ILE D C     1 
ATOM   10913 O O     . ILE C 3 72   ? 199.532 384.653 232.930 1.00 145.58 ? 53   ILE D O     1 
ATOM   10914 C CB    . ILE C 3 72   ? 201.592 386.844 234.396 1.00 145.58 ? 53   ILE D CB    1 
ATOM   10915 C CG1   . ILE C 3 72   ? 202.294 388.089 233.851 1.00 145.58 ? 53   ILE D CG1   1 
ATOM   10916 C CG2   . ILE C 3 72   ? 202.361 385.588 234.013 1.00 145.58 ? 53   ILE D CG2   1 
ATOM   10917 C CD1   . ILE C 3 72   ? 202.263 388.196 232.342 1.00 145.58 ? 53   ILE D CD1   1 
ATOM   10918 N N     . ASN C 3 73   ? 199.152 384.929 235.131 1.00 146.52 ? 54   ASN D N     1 
ATOM   10919 C CA    . ASN C 3 73   ? 198.594 383.588 235.273 1.00 146.52 ? 54   ASN D CA    1 
ATOM   10920 C C     . ASN C 3 73   ? 197.306 383.432 234.473 1.00 146.52 ? 54   ASN D C     1 
ATOM   10921 O O     . ASN C 3 73   ? 197.088 382.398 233.831 1.00 146.52 ? 54   ASN D O     1 
ATOM   10922 C CB    . ASN C 3 73   ? 198.350 383.277 236.750 1.00 146.52 ? 54   ASN D CB    1 
ATOM   10923 C CG    . ASN C 3 73   ? 198.298 381.788 237.030 1.00 146.52 ? 54   ASN D CG    1 
ATOM   10924 O OD1   . ASN C 3 73   ? 198.938 380.992 236.343 1.00 146.52 ? 54   ASN D OD1   1 
ATOM   10925 N ND2   . ASN C 3 73   ? 197.532 381.403 238.045 1.00 146.52 ? 54   ASN D ND2   1 
ATOM   10926 N N     . GLU C 3 74   ? 196.437 384.446 234.502 1.00 148.24 ? 55   GLU D N     1 
ATOM   10927 C CA    . GLU C 3 74   ? 195.166 384.348 233.792 1.00 148.24 ? 55   GLU D CA    1 
ATOM   10928 C C     . GLU C 3 74   ? 195.369 384.353 232.282 1.00 148.24 ? 55   GLU D C     1 
ATOM   10929 O O     . GLU C 3 74   ? 194.737 383.571 231.562 1.00 148.24 ? 55   GLU D O     1 
ATOM   10930 C CB    . GLU C 3 74   ? 194.241 385.490 234.214 1.00 148.24 ? 55   GLU D CB    1 
ATOM   10931 C CG    . GLU C 3 74   ? 193.101 385.754 233.246 1.00 148.24 ? 55   GLU D CG    1 
ATOM   10932 C CD    . GLU C 3 74   ? 192.289 386.974 233.624 1.00 148.24 ? 55   GLU D CD    1 
ATOM   10933 O OE1   . GLU C 3 74   ? 191.201 386.810 234.216 1.00 148.24 ? 55   GLU D OE1   1 
ATOM   10934 O OE2   . GLU C 3 74   ? 192.741 388.099 233.329 1.00 148.24 ? 55   GLU D OE2   1 
ATOM   10935 N N     . VAL C 3 75   ? 196.244 385.231 231.782 1.00 144.81 ? 56   VAL D N     1 
ATOM   10936 C CA    . VAL C 3 75   ? 196.506 385.281 230.345 1.00 144.81 ? 56   VAL D CA    1 
ATOM   10937 C C     . VAL C 3 75   ? 197.122 383.971 229.870 1.00 144.81 ? 56   VAL D C     1 
ATOM   10938 O O     . VAL C 3 75   ? 196.726 383.419 228.836 1.00 144.81 ? 56   VAL D O     1 
ATOM   10939 C CB    . VAL C 3 75   ? 197.403 386.486 230.005 1.00 144.81 ? 56   VAL D CB    1 
ATOM   10940 C CG1   . VAL C 3 75   ? 197.880 386.406 228.563 1.00 144.81 ? 56   VAL D CG1   1 
ATOM   10941 C CG2   . VAL C 3 75   ? 196.658 387.788 230.247 1.00 144.81 ? 56   VAL D CG2   1 
ATOM   10942 N N     . ASP C 3 76   ? 198.092 383.453 230.617 1.00 140.96 ? 57   ASP D N     1 
ATOM   10943 C CA    . ASP C 3 76   ? 198.738 382.203 230.248 1.00 140.96 ? 57   ASP D CA    1 
ATOM   10944 C C     . ASP C 3 76   ? 197.775 381.030 230.401 1.00 140.96 ? 57   ASP D C     1 
ATOM   10945 O O     . ASP C 3 76   ? 196.881 381.035 231.251 1.00 140.96 ? 57   ASP D O     1 
ATOM   10946 C CB    . ASP C 3 76   ? 199.980 381.973 231.109 1.00 140.96 ? 57   ASP D CB    1 
ATOM   10947 C CG    . ASP C 3 76   ? 201.005 381.090 230.430 1.00 140.96 ? 57   ASP D CG    1 
ATOM   10948 O OD1   . ASP C 3 76   ? 200.635 380.360 229.486 1.00 140.96 ? 57   ASP D OD1   1 
ATOM   10949 O OD2   . ASP C 3 76   ? 202.182 381.123 230.844 1.00 140.96 ? 57   ASP D OD2   1 
ATOM   10950 N N     . ALA C 3 77   ? 197.968 380.015 229.559 1.00 137.30 ? 58   ALA D N     1 
ATOM   10951 C CA    . ALA C 3 77   ? 197.149 378.812 229.620 1.00 137.30 ? 58   ALA D CA    1 
ATOM   10952 C C     . ALA C 3 77   ? 197.596 377.843 230.705 1.00 137.30 ? 58   ALA D C     1 
ATOM   10953 O O     . ALA C 3 77   ? 196.851 376.910 231.025 1.00 137.30 ? 58   ALA D O     1 
ATOM   10954 C CB    . ALA C 3 77   ? 197.156 378.101 228.264 1.00 137.30 ? 58   ALA D CB    1 
ATOM   10955 N N     . ASP C 3 78   ? 198.783 378.037 231.276 1.00 134.58 ? 59   ASP D N     1 
ATOM   10956 C CA    . ASP C 3 78   ? 199.296 377.171 232.329 1.00 134.58 ? 59   ASP D CA    1 
ATOM   10957 C C     . ASP C 3 78   ? 200.143 378.018 233.273 1.00 134.58 ? 59   ASP D C     1 
ATOM   10958 O O     . ASP C 3 78   ? 200.126 379.251 233.219 1.00 134.58 ? 59   ASP D O     1 
ATOM   10959 C CB    . ASP C 3 78   ? 200.079 375.993 231.732 1.00 134.58 ? 59   ASP D CB    1 
ATOM   10960 C CG    . ASP C 3 78   ? 200.872 376.385 230.501 1.00 134.58 ? 59   ASP D CG    1 
ATOM   10961 O OD1   . ASP C 3 78   ? 200.870 377.582 230.147 1.00 134.58 ? 59   ASP D OD1   1 
ATOM   10962 O OD2   . ASP C 3 78   ? 201.499 375.495 229.889 1.00 134.58 ? 59   ASP D OD2   1 
ATOM   10963 N N     . GLY C 3 79   ? 200.891 377.348 234.146 1.00 125.02 ? 60   GLY D N     1 
ATOM   10964 C CA    . GLY C 3 79   ? 201.681 378.031 235.152 1.00 125.02 ? 60   GLY D CA    1 
ATOM   10965 C C     . GLY C 3 79   ? 203.138 378.223 234.783 1.00 125.02 ? 60   GLY D C     1 
ATOM   10966 O O     . GLY C 3 79   ? 203.976 378.452 235.661 1.00 125.02 ? 60   GLY D O     1 
ATOM   10967 N N     . ASN C 3 80   ? 203.457 378.128 233.490 1.00 129.60 ? 61   ASN D N     1 
ATOM   10968 C CA    . ASN C 3 80   ? 204.839 378.298 233.055 1.00 129.60 ? 61   ASN D CA    1 
ATOM   10969 C C     . ASN C 3 80   ? 205.353 379.712 233.296 1.00 129.60 ? 61   ASN D C     1 
ATOM   10970 O O     . ASN C 3 80   ? 206.570 379.910 233.389 1.00 129.60 ? 61   ASN D O     1 
ATOM   10971 C CB    . ASN C 3 80   ? 204.974 377.928 231.575 1.00 129.60 ? 61   ASN D CB    1 
ATOM   10972 C CG    . ASN C 3 80   ? 204.293 378.924 230.656 1.00 129.60 ? 61   ASN D CG    1 
ATOM   10973 O OD1   . ASN C 3 80   ? 204.831 379.993 230.371 1.00 129.60 ? 61   ASN D OD1   1 
ATOM   10974 N ND2   . ASN C 3 80   ? 203.101 378.576 230.188 1.00 129.60 ? 61   ASN D ND2   1 
ATOM   10975 N N     . GLY C 3 81   ? 204.461 380.695 233.400 1.00 127.59 ? 62   GLY D N     1 
ATOM   10976 C CA    . GLY C 3 81   ? 204.871 382.047 233.723 1.00 127.59 ? 62   GLY D CA    1 
ATOM   10977 C C     . GLY C 3 81   ? 205.455 382.842 232.578 1.00 127.59 ? 62   GLY D C     1 
ATOM   10978 O O     . GLY C 3 81   ? 206.082 383.877 232.816 1.00 127.59 ? 62   GLY D O     1 
ATOM   10979 N N     . THR C 3 82   ? 205.270 382.392 231.340 1.00 131.39 ? 63   THR D N     1 
ATOM   10980 C CA    . THR C 3 82   ? 205.755 383.108 230.170 1.00 131.39 ? 63   THR D CA    1 
ATOM   10981 C C     . THR C 3 82   ? 204.632 383.244 229.153 1.00 131.39 ? 63   THR D C     1 
ATOM   10982 O O     . THR C 3 82   ? 203.872 382.302 228.912 1.00 131.39 ? 63   THR D O     1 
ATOM   10983 C CB    . THR C 3 82   ? 206.956 382.399 229.524 1.00 131.39 ? 63   THR D CB    1 
ATOM   10984 O OG1   . THR C 3 82   ? 206.677 380.999 229.399 1.00 131.39 ? 63   THR D OG1   1 
ATOM   10985 C CG2   . THR C 3 82   ? 208.207 382.590 230.368 1.00 131.39 ? 63   THR D CG2   1 
ATOM   10986 N N     . ILE C 3 83   ? 204.539 384.427 228.552 1.00 131.58 ? 64   ILE D N     1 
ATOM   10987 C CA    . ILE C 3 83   ? 203.527 384.731 227.548 1.00 131.58 ? 64   ILE D CA    1 
ATOM   10988 C C     . ILE C 3 83   ? 204.216 384.866 226.197 1.00 131.58 ? 64   ILE D C     1 
ATOM   10989 O O     . ILE C 3 83   ? 205.262 385.517 226.087 1.00 131.58 ? 64   ILE D O     1 
ATOM   10990 C CB    . ILE C 3 83   ? 202.731 386.001 227.905 1.00 131.58 ? 64   ILE D CB    1 
ATOM   10991 C CG1   . ILE C 3 83   ? 203.662 387.202 228.096 1.00 131.58 ? 64   ILE D CG1   1 
ATOM   10992 C CG2   . ILE C 3 83   ? 201.894 385.770 229.154 1.00 131.58 ? 64   ILE D CG2   1 
ATOM   10993 C CD1   . ILE C 3 83   ? 202.951 388.452 228.569 1.00 131.58 ? 64   ILE D CD1   1 
ATOM   10994 N N     . ASP C 3 84   ? 203.644 384.230 225.180 1.00 128.13 ? 65   ASP D N     1 
ATOM   10995 C CA    . ASP C 3 84   ? 204.231 384.175 223.851 1.00 128.13 ? 65   ASP D CA    1 
ATOM   10996 C C     . ASP C 3 84   ? 203.401 384.986 222.864 1.00 128.13 ? 65   ASP D C     1 
ATOM   10997 O O     . ASP C 3 84   ? 202.303 385.456 223.174 1.00 128.13 ? 65   ASP D O     1 
ATOM   10998 C CB    . ASP C 3 84   ? 204.346 382.725 223.366 1.00 128.13 ? 65   ASP D CB    1 
ATOM   10999 C CG    . ASP C 3 84   ? 205.767 382.200 223.430 1.00 128.13 ? 65   ASP D CG    1 
ATOM   11000 O OD1   . ASP C 3 84   ? 206.701 383.020 223.549 1.00 128.13 ? 65   ASP D OD1   1 
ATOM   11001 O OD2   . ASP C 3 84   ? 205.949 380.967 223.363 1.00 128.13 ? 65   ASP D OD2   1 
ATOM   11002 N N     . PHE C 3 85   ? 203.954 385.150 221.662 1.00 124.89 ? 66   PHE D N     1 
ATOM   11003 C CA    . PHE C 3 85   ? 203.233 385.854 220.605 1.00 124.89 ? 66   PHE D CA    1 
ATOM   11004 C C     . PHE C 3 85   ? 201.916 385.184 220.220 1.00 124.89 ? 66   PHE D C     1 
ATOM   11005 O O     . PHE C 3 85   ? 200.921 385.911 220.049 1.00 124.89 ? 66   PHE D O     1 
ATOM   11006 C CB    . PHE C 3 85   ? 204.143 386.020 219.380 1.00 124.89 ? 66   PHE D CB    1 
ATOM   11007 N N     . PRO C 3 86   ? 201.831 383.857 220.039 1.00 127.76 ? 67   PRO D N     1 
ATOM   11008 C CA    . PRO C 3 86   ? 200.509 383.259 219.777 1.00 127.76 ? 67   PRO D CA    1 
ATOM   11009 C C     . PRO C 3 86   ? 199.506 383.510 220.889 1.00 127.76 ? 67   PRO D C     1 
ATOM   11010 O O     . PRO C 3 86   ? 198.313 383.684 220.613 1.00 127.76 ? 67   PRO D O     1 
ATOM   11011 C CB    . PRO C 3 86   ? 200.825 381.765 219.619 1.00 127.76 ? 67   PRO D CB    1 
ATOM   11012 C CG    . PRO C 3 86   ? 202.249 381.720 219.211 1.00 127.76 ? 67   PRO D CG    1 
ATOM   11013 C CD    . PRO C 3 86   ? 202.908 382.855 219.929 1.00 127.76 ? 67   PRO D CD    1 
ATOM   11014 N N     . GLU C 3 87   ? 199.958 383.536 222.146 1.00 124.49 ? 68   GLU D N     1 
ATOM   11015 C CA    . GLU C 3 87   ? 199.052 383.844 223.248 1.00 124.49 ? 68   GLU D CA    1 
ATOM   11016 C C     . GLU C 3 87   ? 198.516 385.265 223.137 1.00 124.49 ? 68   GLU D C     1 
ATOM   11017 O O     . GLU C 3 87   ? 197.324 385.507 223.361 1.00 124.49 ? 68   GLU D O     1 
ATOM   11018 C CB    . GLU C 3 87   ? 199.763 383.639 224.585 1.00 124.49 ? 68   GLU D CB    1 
ATOM   11019 N N     . PHE C 3 88   ? 199.382 386.219 222.786 1.00 126.80 ? 69   PHE D N     1 
ATOM   11020 C CA    . PHE C 3 88   ? 198.933 387.595 222.599 1.00 126.80 ? 69   PHE D CA    1 
ATOM   11021 C C     . PHE C 3 88   ? 197.965 387.703 221.429 1.00 126.80 ? 69   PHE D C     1 
ATOM   11022 O O     . PHE C 3 88   ? 196.981 388.450 221.493 1.00 126.80 ? 69   PHE D O     1 
ATOM   11023 C CB    . PHE C 3 88   ? 200.136 388.515 222.390 1.00 126.80 ? 69   PHE D CB    1 
ATOM   11024 C CG    . PHE C 3 88   ? 200.035 389.822 223.123 1.00 126.80 ? 69   PHE D CG    1 
ATOM   11025 C CD1   . PHE C 3 88   ? 200.284 389.889 224.484 1.00 126.80 ? 69   PHE D CD1   1 
ATOM   11026 C CD2   . PHE C 3 88   ? 199.690 390.983 222.452 1.00 126.80 ? 69   PHE D CD2   1 
ATOM   11027 C CE1   . PHE C 3 88   ? 200.192 391.090 225.162 1.00 126.80 ? 69   PHE D CE1   1 
ATOM   11028 C CE2   . PHE C 3 88   ? 199.596 392.188 223.125 1.00 126.80 ? 69   PHE D CE2   1 
ATOM   11029 C CZ    . PHE C 3 88   ? 199.847 392.241 224.481 1.00 126.80 ? 69   PHE D CZ    1 
ATOM   11030 N N     . LEU C 3 89   ? 198.232 386.970 220.345 1.00 123.00 ? 70   LEU D N     1 
ATOM   11031 C CA    . LEU C 3 89   ? 197.323 386.977 219.203 1.00 123.00 ? 70   LEU D CA    1 
ATOM   11032 C C     . LEU C 3 89   ? 195.959 386.412 219.580 1.00 123.00 ? 70   LEU D C     1 
ATOM   11033 O O     . LEU C 3 89   ? 194.921 386.950 219.175 1.00 123.00 ? 70   LEU D O     1 
ATOM   11034 C CB    . LEU C 3 89   ? 197.929 386.185 218.043 1.00 123.00 ? 70   LEU D CB    1 
ATOM   11035 C CG    . LEU C 3 89   ? 198.640 386.986 216.950 1.00 123.00 ? 70   LEU D CG    1 
ATOM   11036 C CD1   . LEU C 3 89   ? 197.646 387.849 216.187 1.00 123.00 ? 70   LEU D CD1   1 
ATOM   11037 C CD2   . LEU C 3 89   ? 199.760 387.835 217.533 1.00 123.00 ? 70   LEU D CD2   1 
ATOM   11038 N N     . THR C 3 90   ? 195.941 385.321 220.349 1.00 123.87 ? 71   THR D N     1 
ATOM   11039 C CA    . THR C 3 90   ? 194.676 384.747 220.797 1.00 123.87 ? 71   THR D CA    1 
ATOM   11040 C C     . THR C 3 90   ? 193.931 385.706 221.718 1.00 123.87 ? 71   THR D C     1 
ATOM   11041 O O     . THR C 3 90   ? 192.705 385.838 221.629 1.00 123.87 ? 71   THR D O     1 
ATOM   11042 C CB    . THR C 3 90   ? 194.923 383.412 221.500 1.00 123.87 ? 71   THR D CB    1 
ATOM   11043 O OG1   . THR C 3 90   ? 195.763 382.587 220.683 1.00 123.87 ? 71   THR D OG1   1 
ATOM   11044 C CG2   . THR C 3 90   ? 193.607 382.691 221.753 1.00 123.87 ? 71   THR D CG2   1 
ATOM   11045 N N     . MET C 3 91   ? 194.657 386.381 222.614 1.00 124.10 ? 72   MET D N     1 
ATOM   11046 C CA    . MET C 3 91   ? 194.024 387.351 223.502 1.00 124.10 ? 72   MET D CA    1 
ATOM   11047 C C     . MET C 3 91   ? 193.428 388.513 222.717 1.00 124.10 ? 72   MET D C     1 
ATOM   11048 O O     . MET C 3 91   ? 192.329 388.986 223.031 1.00 124.10 ? 72   MET D O     1 
ATOM   11049 C CB    . MET C 3 91   ? 195.035 387.858 224.530 1.00 124.10 ? 72   MET D CB    1 
ATOM   11050 N N     . MET C 3 92   ? 194.141 388.990 221.693 1.00 125.74 ? 73   MET D N     1 
ATOM   11051 C CA    . MET C 3 92   ? 193.624 390.085 220.879 1.00 125.74 ? 73   MET D CA    1 
ATOM   11052 C C     . MET C 3 92   ? 192.446 389.643 220.021 1.00 125.74 ? 73   MET D C     1 
ATOM   11053 O O     . MET C 3 92   ? 191.689 390.485 219.525 1.00 125.74 ? 73   MET D O     1 
ATOM   11054 C CB    . MET C 3 92   ? 194.737 390.656 219.999 1.00 125.74 ? 73   MET D CB    1 
ATOM   11055 N N     . ALA C 3 93   ? 192.273 388.333 219.833 1.00 128.00 ? 74   ALA D N     1 
ATOM   11056 C CA    . ALA C 3 93   ? 191.180 387.818 219.018 1.00 128.00 ? 74   ALA D CA    1 
ATOM   11057 C C     . ALA C 3 93   ? 189.865 387.726 219.779 1.00 128.00 ? 74   ALA D C     1 
ATOM   11058 O O     . ALA C 3 93   ? 188.849 387.358 219.178 1.00 128.00 ? 74   ALA D O     1 
ATOM   11059 C CB    . ALA C 3 93   ? 191.547 386.444 218.456 1.00 128.00 ? 74   ALA D CB    1 
ATOM   11060 N N     . ARG C 3 94   ? 189.857 388.040 221.073 1.00 133.52 ? 75   ARG D N     1 
ATOM   11061 C CA    . ARG C 3 94   ? 188.630 387.967 221.854 1.00 133.52 ? 75   ARG D CA    1 
ATOM   11062 C C     . ARG C 3 94   ? 187.618 388.997 221.366 1.00 133.52 ? 75   ARG D C     1 
ATOM   11063 O O     . ARG C 3 94   ? 187.982 390.061 220.856 1.00 133.52 ? 75   ARG D O     1 
ATOM   11064 C CB    . ARG C 3 94   ? 188.934 388.181 223.339 1.00 133.52 ? 75   ARG D CB    1 
ATOM   11065 C CG    . ARG C 3 94   ? 189.235 389.624 223.717 1.00 133.52 ? 75   ARG D CG    1 
ATOM   11066 C CD    . ARG C 3 94   ? 189.046 389.862 225.206 1.00 133.52 ? 75   ARG D CD    1 
ATOM   11067 N NE    . ARG C 3 94   ? 189.067 391.283 225.535 1.00 133.52 ? 75   ARG D NE    1 
ATOM   11068 C CZ    . ARG C 3 94   ? 188.484 391.815 226.600 1.00 133.52 ? 75   ARG D CZ    1 
ATOM   11069 N NH1   . ARG C 3 94   ? 187.818 391.070 227.468 1.00 133.52 ? 75   ARG D NH1   1 
ATOM   11070 N NH2   . ARG C 3 94   ? 188.570 393.127 226.800 1.00 133.52 ? 75   ARG D NH2   1 
ATOM   11071 N N     . LYS C 3 95   ? 186.338 388.668 221.514 1.00 126.40 ? 76   LYS D N     1 
ATOM   11072 C CA    . LYS C 3 95   ? 185.247 389.543 221.109 1.00 126.40 ? 76   LYS D CA    1 
ATOM   11073 C C     . LYS C 3 95   ? 184.676 390.231 222.341 1.00 126.40 ? 76   LYS D C     1 
ATOM   11074 O O     . LYS C 3 95   ? 184.285 389.564 223.305 1.00 126.40 ? 76   LYS D O     1 
ATOM   11075 N N     . MET C 3 96   ? 184.629 391.560 222.305 1.00 126.39 ? 77   MET D N     1 
ATOM   11076 C CA    . MET C 3 96   ? 184.137 392.353 223.423 1.00 126.39 ? 77   MET D CA    1 
ATOM   11077 C C     . MET C 3 96   ? 182.652 392.675 223.319 1.00 126.39 ? 77   MET D C     1 
ATOM   11078 O O     . MET C 3 96   ? 182.114 393.340 224.210 1.00 126.39 ? 77   MET D O     1 
ATOM   11079 C CB    . MET C 3 96   ? 184.938 393.654 223.536 1.00 126.39 ? 77   MET D CB    1 
ATOM   11080 N N     . LYS C 3 97   ? 181.976 392.221 222.265 1.00 127.00 ? 78   LYS D N     1 
ATOM   11081 C CA    . LYS C 3 97   ? 180.560 392.517 222.091 1.00 127.00 ? 78   LYS D CA    1 
ATOM   11082 C C     . LYS C 3 97   ? 180.357 393.990 221.762 1.00 127.00 ? 78   LYS D C     1 
ATOM   11083 O O     . LYS C 3 97   ? 181.003 394.524 220.855 1.00 127.00 ? 78   LYS D O     1 
ATOM   11084 N N     . ASP C 3 98   ? 179.462 394.656 222.491 1.00 136.46 ? 79   ASP D N     1 
ATOM   11085 C CA    . ASP C 3 98   ? 179.158 396.062 222.261 1.00 136.46 ? 79   ASP D CA    1 
ATOM   11086 C C     . ASP C 3 98   ? 179.540 396.955 223.433 1.00 136.46 ? 79   ASP D C     1 
ATOM   11087 O O     . ASP C 3 98   ? 180.295 397.915 223.253 1.00 136.46 ? 79   ASP D O     1 
ATOM   11088 C CB    . ASP C 3 98   ? 177.664 396.229 221.944 1.00 136.46 ? 79   ASP D CB    1 
ATOM   11089 C CG    . ASP C 3 98   ? 177.192 397.665 222.084 1.00 136.46 ? 79   ASP D CG    1 
ATOM   11090 O OD1   . ASP C 3 98   ? 177.271 398.416 221.089 1.00 136.46 ? 79   ASP D OD1   1 
ATOM   11091 O OD2   . ASP C 3 98   ? 176.743 398.043 223.187 1.00 136.46 ? 79   ASP D OD2   1 
ATOM   11092 N N     . THR C 3 99   ? 179.037 396.659 224.635 1.00 137.88 ? 80   THR D N     1 
ATOM   11093 C CA    . THR C 3 99   ? 179.268 397.538 225.780 1.00 137.88 ? 80   THR D CA    1 
ATOM   11094 C C     . THR C 3 99   ? 180.748 397.613 226.140 1.00 137.88 ? 80   THR D C     1 
ATOM   11095 O O     . THR C 3 99   ? 181.271 398.696 226.436 1.00 137.88 ? 80   THR D O     1 
ATOM   11096 C CB    . THR C 3 99   ? 178.451 397.063 226.981 1.00 137.88 ? 80   THR D CB    1 
ATOM   11097 O OG1   . THR C 3 99   ? 178.788 395.703 227.283 1.00 137.88 ? 80   THR D OG1   1 
ATOM   11098 C CG2   . THR C 3 99   ? 176.962 397.156 226.682 1.00 137.88 ? 80   THR D CG2   1 
ATOM   11099 N N     . ASP C 3 100  ? 181.437 396.470 226.129 1.00 138.95 ? 81   ASP D N     1 
ATOM   11100 C CA    . ASP C 3 100  ? 182.861 396.471 226.448 1.00 138.95 ? 81   ASP D CA    1 
ATOM   11101 C C     . ASP C 3 100  ? 183.651 397.274 225.422 1.00 138.95 ? 81   ASP D C     1 
ATOM   11102 O O     . ASP C 3 100  ? 184.637 397.930 225.768 1.00 138.95 ? 81   ASP D O     1 
ATOM   11103 C CB    . ASP C 3 100  ? 183.384 395.038 226.534 1.00 138.95 ? 81   ASP D CB    1 
ATOM   11104 C CG    . ASP C 3 100  ? 183.553 394.565 227.965 1.00 138.95 ? 81   ASP D CG    1 
ATOM   11105 O OD1   . ASP C 3 100  ? 183.204 395.328 228.890 1.00 138.95 ? 81   ASP D OD1   1 
ATOM   11106 O OD2   . ASP C 3 100  ? 184.036 393.431 228.164 1.00 138.95 ? 81   ASP D OD2   1 
ATOM   11107 N N     . SER C 3 101  ? 183.224 397.245 224.158 1.00 136.99 ? 82   SER D N     1 
ATOM   11108 C CA    . SER C 3 101  ? 183.926 397.996 223.121 1.00 136.99 ? 82   SER D CA    1 
ATOM   11109 C C     . SER C 3 101  ? 183.840 399.499 223.369 1.00 136.99 ? 82   SER D C     1 
ATOM   11110 O O     . SER C 3 101  ? 184.852 400.210 223.305 1.00 136.99 ? 82   SER D O     1 
ATOM   11111 C CB    . SER C 3 101  ? 183.359 397.642 221.745 1.00 136.99 ? 82   SER D CB    1 
ATOM   11112 O OG    . SER C 3 101  ? 184.055 396.549 221.173 1.00 136.99 ? 82   SER D OG    1 
ATOM   11113 N N     . GLU C 3 102  ? 182.635 400.004 223.652 1.00 139.86 ? 83   GLU D N     1 
ATOM   11114 C CA    . GLU C 3 102  ? 182.492 401.434 223.910 1.00 139.86 ? 83   GLU D CA    1 
ATOM   11115 C C     . GLU C 3 102  ? 183.190 401.828 225.204 1.00 139.86 ? 83   GLU D C     1 
ATOM   11116 O O     . GLU C 3 102  ? 183.788 402.906 225.289 1.00 139.86 ? 83   GLU D O     1 
ATOM   11117 C CB    . GLU C 3 102  ? 181.018 401.841 223.943 1.00 139.86 ? 83   GLU D CB    1 
ATOM   11118 C CG    . GLU C 3 102  ? 180.070 400.786 224.466 1.00 139.86 ? 83   GLU D CG    1 
ATOM   11119 C CD    . GLU C 3 102  ? 178.630 401.258 224.493 1.00 139.86 ? 83   GLU D CD    1 
ATOM   11120 O OE1   . GLU C 3 102  ? 178.240 401.927 225.472 1.00 139.86 ? 83   GLU D OE1   1 
ATOM   11121 O OE2   . GLU C 3 102  ? 177.887 400.960 223.533 1.00 139.86 ? 83   GLU D OE2   1 
ATOM   11122 N N     . GLU C 3 103  ? 183.138 400.964 226.222 1.00 141.27 ? 84   GLU D N     1 
ATOM   11123 C CA    . GLU C 3 103  ? 183.871 401.247 227.452 1.00 141.27 ? 84   GLU D CA    1 
ATOM   11124 C C     . GLU C 3 103  ? 185.370 401.343 227.187 1.00 141.27 ? 84   GLU D C     1 
ATOM   11125 O O     . GLU C 3 103  ? 186.043 402.251 227.692 1.00 141.27 ? 84   GLU D O     1 
ATOM   11126 C CB    . GLU C 3 103  ? 183.576 400.171 228.498 1.00 141.27 ? 84   GLU D CB    1 
ATOM   11127 C CG    . GLU C 3 103  ? 184.465 400.240 229.730 1.00 141.27 ? 84   GLU D CG    1 
ATOM   11128 C CD    . GLU C 3 103  ? 183.831 399.586 230.942 1.00 141.27 ? 84   GLU D CD    1 
ATOM   11129 O OE1   . GLU C 3 103  ? 183.193 398.524 230.781 1.00 141.27 ? 84   GLU D OE1   1 
ATOM   11130 O OE2   . GLU C 3 103  ? 183.972 400.133 232.056 1.00 141.27 ? 84   GLU D OE2   1 
ATOM   11131 N N     . GLU C 3 104  ? 185.906 400.423 226.381 1.00 140.18 ? 85   GLU D N     1 
ATOM   11132 C CA    . GLU C 3 104  ? 187.332 400.430 226.076 1.00 140.18 ? 85   GLU D CA    1 
ATOM   11133 C C     . GLU C 3 104  ? 187.729 401.670 225.286 1.00 140.18 ? 85   GLU D C     1 
ATOM   11134 O O     . GLU C 3 104  ? 188.759 402.291 225.573 1.00 140.18 ? 85   GLU D O     1 
ATOM   11135 C CB    . GLU C 3 104  ? 187.703 399.160 225.309 1.00 140.18 ? 85   GLU D CB    1 
ATOM   11136 C CG    . GLU C 3 104  ? 188.932 399.295 224.428 1.00 140.18 ? 85   GLU D CG    1 
ATOM   11137 C CD    . GLU C 3 104  ? 189.559 397.956 224.102 1.00 140.18 ? 85   GLU D CD    1 
ATOM   11138 O OE1   . GLU C 3 104  ? 189.173 397.347 223.082 1.00 140.18 ? 85   GLU D OE1   1 
ATOM   11139 O OE2   . GLU C 3 104  ? 190.437 397.511 224.869 1.00 140.18 ? 85   GLU D OE2   1 
ATOM   11140 N N     . ILE C 3 105  ? 186.930 402.048 224.284 1.00 137.19 ? 86   ILE D N     1 
ATOM   11141 C CA    . ILE C 3 105  ? 187.284 403.221 223.487 1.00 137.19 ? 86   ILE D CA    1 
ATOM   11142 C C     . ILE C 3 105  ? 187.161 404.491 224.323 1.00 137.19 ? 86   ILE D C     1 
ATOM   11143 O O     . ILE C 3 105  ? 187.960 405.424 224.176 1.00 137.19 ? 86   ILE D O     1 
ATOM   11144 C CB    . ILE C 3 105  ? 186.446 403.292 222.193 1.00 137.19 ? 86   ILE D CB    1 
ATOM   11145 C CG1   . ILE C 3 105  ? 184.970 403.560 222.490 1.00 137.19 ? 86   ILE D CG1   1 
ATOM   11146 C CG2   . ILE C 3 105  ? 186.622 402.021 221.371 1.00 137.19 ? 86   ILE D CG2   1 
ATOM   11147 C CD1   . ILE C 3 105  ? 184.128 403.774 221.251 1.00 137.19 ? 86   ILE D CD1   1 
ATOM   11148 N N     . ARG C 3 106  ? 186.176 404.544 225.226 1.00 139.93 ? 87   ARG D N     1 
ATOM   11149 C CA    . ARG C 3 106  ? 186.058 405.692 226.120 1.00 139.93 ? 87   ARG D CA    1 
ATOM   11150 C C     . ARG C 3 106  ? 187.258 405.787 227.053 1.00 139.93 ? 87   ARG D C     1 
ATOM   11151 O O     . ARG C 3 106  ? 187.789 406.880 227.283 1.00 139.93 ? 87   ARG D O     1 
ATOM   11152 C CB    . ARG C 3 106  ? 184.760 405.601 226.922 1.00 139.93 ? 87   ARG D CB    1 
ATOM   11153 C CG    . ARG C 3 106  ? 183.734 406.665 226.568 1.00 139.93 ? 87   ARG D CG    1 
ATOM   11154 C CD    . ARG C 3 106  ? 182.859 406.224 225.407 1.00 139.93 ? 87   ARG D CD    1 
ATOM   11155 N NE    . ARG C 3 106  ? 181.788 407.177 225.139 1.00 139.93 ? 87   ARG D NE    1 
ATOM   11156 C CZ    . ARG C 3 106  ? 181.075 407.208 224.022 1.00 139.93 ? 87   ARG D CZ    1 
ATOM   11157 N NH1   . ARG C 3 106  ? 181.293 406.349 223.039 1.00 139.93 ? 87   ARG D NH1   1 
ATOM   11158 N NH2   . ARG C 3 106  ? 180.120 408.123 223.886 1.00 139.93 ? 87   ARG D NH2   1 
ATOM   11159 N N     . GLU C 3 107  ? 187.701 404.652 227.601 1.00 138.80 ? 88   GLU D N     1 
ATOM   11160 C CA    . GLU C 3 107  ? 188.878 404.659 228.463 1.00 138.80 ? 88   GLU D CA    1 
ATOM   11161 C C     . GLU C 3 107  ? 190.123 405.084 227.694 1.00 138.80 ? 88   GLU D C     1 
ATOM   11162 O O     . GLU C 3 107  ? 190.949 405.849 228.208 1.00 138.80 ? 88   GLU D O     1 
ATOM   11163 C CB    . GLU C 3 107  ? 189.079 403.280 229.089 1.00 138.80 ? 88   GLU D CB    1 
ATOM   11164 N N     . ALA C 3 108  ? 190.276 404.594 226.461 1.00 137.03 ? 89   ALA D N     1 
ATOM   11165 C CA    . ALA C 3 108  ? 191.424 404.981 225.647 1.00 137.03 ? 89   ALA D CA    1 
ATOM   11166 C C     . ALA C 3 108  ? 191.407 406.473 225.343 1.00 137.03 ? 89   ALA D C     1 
ATOM   11167 O O     . ALA C 3 108  ? 192.448 407.138 225.400 1.00 137.03 ? 89   ALA D O     1 
ATOM   11168 C CB    . ALA C 3 108  ? 191.448 404.167 224.353 1.00 137.03 ? 89   ALA D CB    1 
ATOM   11169 N N     . PHE C 3 109  ? 190.232 407.017 225.015 1.00 140.03 ? 90   PHE D N     1 
ATOM   11170 C CA    . PHE C 3 109  ? 190.123 408.451 224.767 1.00 140.03 ? 90   PHE D CA    1 
ATOM   11171 C C     . PHE C 3 109  ? 190.446 409.252 226.022 1.00 140.03 ? 90   PHE D C     1 
ATOM   11172 O O     . PHE C 3 109  ? 191.140 410.273 225.952 1.00 140.03 ? 90   PHE D O     1 
ATOM   11173 C CB    . PHE C 3 109  ? 188.722 408.790 224.258 1.00 140.03 ? 90   PHE D CB    1 
ATOM   11174 C CG    . PHE C 3 109  ? 188.643 410.098 223.523 1.00 140.03 ? 90   PHE D CG    1 
ATOM   11175 C CD1   . PHE C 3 109  ? 189.789 410.710 223.041 1.00 140.03 ? 90   PHE D CD1   1 
ATOM   11176 C CD2   . PHE C 3 109  ? 187.421 410.717 223.314 1.00 140.03 ? 90   PHE D CD2   1 
ATOM   11177 C CE1   . PHE C 3 109  ? 189.719 411.913 222.365 1.00 140.03 ? 90   PHE D CE1   1 
ATOM   11178 C CE2   . PHE C 3 109  ? 187.344 411.921 222.638 1.00 140.03 ? 90   PHE D CE2   1 
ATOM   11179 C CZ    . PHE C 3 109  ? 188.495 412.519 222.163 1.00 140.03 ? 90   PHE D CZ    1 
ATOM   11180 N N     . ARG C 3 110  ? 189.953 408.805 227.180 1.00 137.53 ? 91   ARG D N     1 
ATOM   11181 C CA    . ARG C 3 110  ? 190.232 409.509 228.427 1.00 137.53 ? 91   ARG D CA    1 
ATOM   11182 C C     . ARG C 3 110  ? 191.721 409.497 228.748 1.00 137.53 ? 91   ARG D C     1 
ATOM   11183 O O     . ARG C 3 110  ? 192.275 410.506 229.201 1.00 137.53 ? 91   ARG D O     1 
ATOM   11184 C CB    . ARG C 3 110  ? 189.431 408.888 229.571 1.00 137.53 ? 91   ARG D CB    1 
ATOM   11185 N N     . VAL C 3 111  ? 192.385 408.360 228.529 1.00 135.18 ? 92   VAL D N     1 
ATOM   11186 C CA    . VAL C 3 111  ? 193.827 408.287 228.753 1.00 135.18 ? 92   VAL D CA    1 
ATOM   11187 C C     . VAL C 3 111  ? 194.564 409.206 227.786 1.00 135.18 ? 92   VAL D C     1 
ATOM   11188 O O     . VAL C 3 111  ? 195.492 409.926 228.174 1.00 135.18 ? 92   VAL D O     1 
ATOM   11189 C CB    . VAL C 3 111  ? 194.315 406.831 228.638 1.00 135.18 ? 92   VAL D CB    1 
ATOM   11190 C CG1   . VAL C 3 111  ? 195.835 406.775 228.631 1.00 135.18 ? 92   VAL D CG1   1 
ATOM   11191 C CG2   . VAL C 3 111  ? 193.758 405.995 229.780 1.00 135.18 ? 92   VAL D CG2   1 
ATOM   11192 N N     . PHE C 3 112  ? 194.158 409.203 226.513 1.00 134.66 ? 93   PHE D N     1 
ATOM   11193 C CA    . PHE C 3 112  ? 194.818 410.048 225.524 1.00 134.66 ? 93   PHE D CA    1 
ATOM   11194 C C     . PHE C 3 112  ? 194.515 411.525 225.745 1.00 134.66 ? 93   PHE D C     1 
ATOM   11195 O O     . PHE C 3 112  ? 195.362 412.378 225.457 1.00 134.66 ? 93   PHE D O     1 
ATOM   11196 C CB    . PHE C 3 112  ? 194.403 409.628 224.114 1.00 134.66 ? 93   PHE D CB    1 
ATOM   11197 N N     . ASP C 3 113  ? 193.328 411.847 226.250 1.00 138.05 ? 94   ASP D N     1 
ATOM   11198 C CA    . ASP C 3 113  ? 192.924 413.237 226.467 1.00 138.05 ? 94   ASP D CA    1 
ATOM   11199 C C     . ASP C 3 113  ? 193.327 413.727 227.855 1.00 138.05 ? 94   ASP D C     1 
ATOM   11200 O O     . ASP C 3 113  ? 192.495 414.170 228.646 1.00 138.05 ? 94   ASP D O     1 
ATOM   11201 C CB    . ASP C 3 113  ? 191.422 413.379 226.251 1.00 138.05 ? 94   ASP D CB    1 
ATOM   11202 C CG    . ASP C 3 113  ? 191.024 414.774 225.812 1.00 138.05 ? 94   ASP D CG    1 
ATOM   11203 O OD1   . ASP C 3 113  ? 191.821 415.713 226.011 1.00 138.05 ? 94   ASP D OD1   1 
ATOM   11204 O OD2   . ASP C 3 113  ? 189.911 414.930 225.268 1.00 138.05 ? 94   ASP D OD2   1 
ATOM   11205 N N     . LYS C 3 114  ? 194.624 413.637 228.160 1.00 132.71 ? 95   LYS D N     1 
ATOM   11206 C CA    . LYS C 3 114  ? 195.114 414.103 229.454 1.00 132.71 ? 95   LYS D CA    1 
ATOM   11207 C C     . LYS C 3 114  ? 194.915 415.605 229.615 1.00 132.71 ? 95   LYS D C     1 
ATOM   11208 O O     . LYS C 3 114  ? 194.505 416.074 230.683 1.00 132.71 ? 95   LYS D O     1 
ATOM   11209 C CB    . LYS C 3 114  ? 196.589 413.735 229.619 1.00 132.71 ? 95   LYS D CB    1 
ATOM   11210 N N     . ASP C 3 115  ? 195.200 416.373 228.567 1.00 133.17 ? 96   ASP D N     1 
ATOM   11211 C CA    . ASP C 3 115  ? 195.024 417.817 228.626 1.00 133.17 ? 96   ASP D CA    1 
ATOM   11212 C C     . ASP C 3 115  ? 193.545 418.182 228.583 1.00 133.17 ? 96   ASP D C     1 
ATOM   11213 O O     . ASP C 3 115  ? 192.713 417.446 228.046 1.00 133.17 ? 96   ASP D O     1 
ATOM   11214 C CB    . ASP C 3 115  ? 195.764 418.492 227.472 1.00 133.17 ? 96   ASP D CB    1 
ATOM   11215 N N     . GLY C 3 116  ? 193.221 419.335 229.162 1.00 134.34 ? 97   GLY D N     1 
ATOM   11216 C CA    . GLY C 3 116  ? 191.852 419.812 229.179 1.00 134.34 ? 97   GLY D CA    1 
ATOM   11217 C C     . GLY C 3 116  ? 191.448 420.517 227.901 1.00 134.34 ? 97   GLY D C     1 
ATOM   11218 O O     . GLY C 3 116  ? 191.158 421.718 227.912 1.00 134.34 ? 97   GLY D O     1 
ATOM   11219 N N     . ASN C 3 117  ? 191.426 419.781 226.788 1.00 141.60 ? 98   ASN D N     1 
ATOM   11220 C CA    . ASN C 3 117  ? 191.065 420.342 225.495 1.00 141.60 ? 98   ASN D CA    1 
ATOM   11221 C C     . ASN C 3 117  ? 189.866 419.674 224.840 1.00 141.60 ? 98   ASN D C     1 
ATOM   11222 O O     . ASN C 3 117  ? 189.274 420.271 223.933 1.00 141.60 ? 98   ASN D O     1 
ATOM   11223 C CB    . ASN C 3 117  ? 192.257 420.270 224.526 1.00 141.60 ? 98   ASN D CB    1 
ATOM   11224 C CG    . ASN C 3 117  ? 192.715 418.848 224.269 1.00 141.60 ? 98   ASN D CG    1 
ATOM   11225 O OD1   . ASN C 3 117  ? 193.171 418.156 225.179 1.00 141.60 ? 98   ASN D OD1   1 
ATOM   11226 N ND2   . ASN C 3 117  ? 192.596 418.404 223.023 1.00 141.60 ? 98   ASN D ND2   1 
ATOM   11227 N N     . GLY C 3 118  ? 189.491 418.469 225.262 1.00 144.73 ? 99   GLY D N     1 
ATOM   11228 C CA    . GLY C 3 118  ? 188.354 417.779 224.692 1.00 144.73 ? 99   GLY D CA    1 
ATOM   11229 C C     . GLY C 3 118  ? 188.622 417.050 223.394 1.00 144.73 ? 99   GLY D C     1 
ATOM   11230 O O     . GLY C 3 118  ? 187.677 416.512 222.801 1.00 144.73 ? 99   GLY D O     1 
ATOM   11231 N N     . TYR C 3 119  ? 189.867 417.011 222.931 1.00 146.06 ? 100  TYR D N     1 
ATOM   11232 C CA    . TYR C 3 119  ? 190.203 416.322 221.691 1.00 146.06 ? 100  TYR D CA    1 
ATOM   11233 C C     . TYR C 3 119  ? 191.477 415.499 221.849 1.00 146.06 ? 100  TYR D C     1 
ATOM   11234 O O     . TYR C 3 119  ? 192.468 415.972 222.407 1.00 146.06 ? 100  TYR D O     1 
ATOM   11235 C CB    . TYR C 3 119  ? 190.362 417.324 220.545 1.00 146.06 ? 100  TYR D CB    1 
ATOM   11236 C CG    . TYR C 3 119  ? 189.059 417.931 220.077 1.00 146.06 ? 100  TYR D CG    1 
ATOM   11237 C CD1   . TYR C 3 119  ? 188.165 417.196 219.309 1.00 146.06 ? 100  TYR D CD1   1 
ATOM   11238 C CD2   . TYR C 3 119  ? 188.723 419.238 220.402 1.00 146.06 ? 100  TYR D CD2   1 
ATOM   11239 C CE1   . TYR C 3 119  ? 186.972 417.746 218.878 1.00 146.06 ? 100  TYR D CE1   1 
ATOM   11240 C CE2   . TYR C 3 119  ? 187.532 419.797 219.976 1.00 146.06 ? 100  TYR D CE2   1 
ATOM   11241 C CZ    . TYR C 3 119  ? 186.661 419.047 219.214 1.00 146.06 ? 100  TYR D CZ    1 
ATOM   11242 O OH    . TYR C 3 119  ? 185.475 419.599 218.788 1.00 146.06 ? 100  TYR D OH    1 
HETATM 11243 P PG    . ATP D 4 .    ? 194.241 347.817 217.371 1.00 98.41  ? 401  ATP C PG    1 
HETATM 11244 O O1G   . ATP D 4 .    ? 194.859 348.246 218.658 1.00 98.41  ? 401  ATP C O1G   1 
HETATM 11245 O O2G   . ATP D 4 .    ? 195.222 347.796 216.194 1.00 98.41  ? 401  ATP C O2G   1 
HETATM 11246 O O3G   . ATP D 4 .    ? 193.006 348.636 216.978 1.00 98.41  ? 401  ATP C O3G   1 
HETATM 11247 P PB    . ATP D 4 .    ? 194.254 344.843 217.754 1.00 98.41  ? 401  ATP C PB    1 
HETATM 11248 O O1B   . ATP D 4 .    ? 193.590 344.219 218.917 1.00 98.41  ? 401  ATP C O1B   1 
HETATM 11249 O O2B   . ATP D 4 .    ? 194.157 344.066 216.440 1.00 98.41  ? 401  ATP C O2B   1 
HETATM 11250 O O3B   . ATP D 4 .    ? 193.707 346.312 217.475 1.00 98.41  ? 401  ATP C O3B   1 
HETATM 11251 P PA    . ATP D 4 .    ? 197.118 345.299 217.157 1.00 98.41  ? 401  ATP C PA    1 
HETATM 11252 O O1A   . ATP D 4 .    ? 198.110 344.242 217.443 1.00 98.41  ? 401  ATP C O1A   1 
HETATM 11253 O O2A   . ATP D 4 .    ? 196.682 345.383 215.693 1.00 98.41  ? 401  ATP C O2A   1 
HETATM 11254 O O3A   . ATP D 4 .    ? 195.798 345.116 218.028 1.00 98.41  ? 401  ATP C O3A   1 
HETATM 11255 O "O5'" . ATP D 4 .    ? 197.635 346.723 217.603 1.00 98.41  ? 401  ATP C "O5'" 1 
HETATM 11256 C "C5'" . ATP D 4 .    ? 198.971 346.910 218.116 1.00 98.41  ? 401  ATP C "C5'" 1 
HETATM 11257 C "C4'" . ATP D 4 .    ? 199.007 346.496 219.566 1.00 98.41  ? 401  ATP C "C4'" 1 
HETATM 11258 O "O4'" . ATP D 4 .    ? 200.366 346.194 219.946 1.00 98.41  ? 401  ATP C "O4'" 1 
HETATM 11259 C "C3'" . ATP D 4 .    ? 198.546 347.559 220.556 1.00 98.41  ? 401  ATP C "C3'" 1 
HETATM 11260 O "O3'" . ATP D 4 .    ? 198.040 346.964 221.746 1.00 98.41  ? 401  ATP C "O3'" 1 
HETATM 11261 C "C2'" . ATP D 4 .    ? 199.835 348.341 220.815 1.00 98.41  ? 401  ATP C "C2'" 1 
HETATM 11262 O "O2'" . ATP D 4 .    ? 199.827 348.963 222.094 1.00 98.41  ? 401  ATP C "O2'" 1 
HETATM 11263 C "C1'" . ATP D 4 .    ? 200.889 347.230 220.763 1.00 98.41  ? 401  ATP C "C1'" 1 
HETATM 11264 N N9    . ATP D 4 .    ? 202.169 347.652 220.204 1.00 98.41  ? 401  ATP C N9    1 
HETATM 11265 C C8    . ATP D 4 .    ? 202.622 347.444 218.927 1.00 98.41  ? 401  ATP C C8    1 
HETATM 11266 N N7    . ATP D 4 .    ? 203.815 347.935 218.695 1.00 98.41  ? 401  ATP C N7    1 
HETATM 11267 C C5    . ATP D 4 .    ? 204.174 348.508 219.906 1.00 98.41  ? 401  ATP C C5    1 
HETATM 11268 C C6    . ATP D 4 .    ? 205.328 349.197 220.326 1.00 98.41  ? 401  ATP C C6    1 
HETATM 11269 N N6    . ATP D 4 .    ? 206.381 349.436 219.538 1.00 98.41  ? 401  ATP C N6    1 
HETATM 11270 N N1    . ATP D 4 .    ? 205.366 349.640 221.603 1.00 98.41  ? 401  ATP C N1    1 
HETATM 11271 C C2    . ATP D 4 .    ? 204.318 349.405 222.396 1.00 98.41  ? 401  ATP C C2    1 
HETATM 11272 N N3    . ATP D 4 .    ? 203.180 348.769 222.112 1.00 98.41  ? 401  ATP C N3    1 
HETATM 11273 C C4    . ATP D 4 .    ? 203.168 348.342 220.845 1.00 98.41  ? 401  ATP C C4    1 
# 
