data_8Z5H
# 
_entry.id   8Z5H 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8Z5H         pdb_00008z5h 10.2210/pdb8z5h/pdb 
WWPDB D_1300046645 ?            ?                   
EMDB  EMD-39774    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-04-23 ? 
2 'EM metadata'     1 0 2025-04-23 ? 
3 'Half map'        1 0 2025-04-23 1 
4 'Half map'        1 0 2025-04-23 2 
5 Image             1 0 2025-04-23 ? 
6 Mask              1 0 2025-04-23 1 
7 'Primary map'     1 0 2025-04-23 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1 1 'Structure model' repository 'Initial release' ? ? 
2 2 'EM metadata'     repository 'Initial release' ? ? 
3 3 'Half map'        repository 'Initial release' ? ? 
4 4 'Half map'        repository 'Initial release' ? ? 
5 5 Image             repository 'Initial release' ? ? 
6 6 Mask              repository 'Initial release' ? ? 
7 7 'Primary map'     repository 'Initial release' ? ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8Z5H 
_pdbx_database_status.recvd_initial_deposition_date   2024-04-18 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBC 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Cryo-EM structure of the hGPR68-Gs complex in pH6.0' 
_pdbx_database_related.db_id          EMD-39774 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              guolu_gl@126.com 
_pdbx_contact_author.name_first         Guo 
_pdbx_contact_author.name_last          Lu-Lu 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-1309-6801 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Zhong, Y.N.' 1 0000-0001-9079-7081 
'Guo, L.L.'   2 0000-0002-1309-6801 
'Yang, F.'    3 0000-0002-3000-2336 
'Sun, J.P.'   4 0000-0003-3572-1580 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'Cryo-EM structure of the hGPR68-Gs complex in pH6.0' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Zhong, Y.N.' 1 0000-0001-9079-7081 
primary 'Guo, L.L.'   2 0000-0002-1309-6801 
primary 'Yang, F.'    3 0000-0002-3000-2336 
primary 'Sun, J.P.'   4 0000-0003-3572-1580 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer man 'Guanine nucleotide-binding protein G(s) subunit alpha isoforms short' 42010.664 1 ? ? ? ? 
2 polymer man 'Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1'     37915.496 1 ? ? ? ? 
3 polymer man 'Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2'    7861.143  1 ? ? ? ? 
4 polymer man 'Ovarian cancer G-protein coupled receptor 1'                          36511.469 1 ? ? ? ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
2 'Transducin beta chain 1'                                                         
3 'G gamma-I'                                                                       
4 'G-protein coupled receptor 68,OGR-1,GPR12A,Sphingosylphosphorylcholine receptor' 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;MMGCTLSAEDKAAVERSKMIEKQLQKDKQVYRATHRLLLLGADNSGKSTIVKQMRIYHVNGYSEEECKQYKAVVYSNTIQ
SIIAIIRAMGRLKIDFGDSARADDARQLFVLAGAAEEGFMTAELAGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDL
DRIAQPNYIPTQQDVLRTRVKTSGIFETKFQVDKVNFHMFDVGAQRDERRKWIQCFNDVTAIIFVVDSSDYNRLQEALND
FKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTAS
GDGRHYCYPHFTCSVDTENARRIFNDCRDIIQRMHLRQYELL
;
;MMGCTLSAEDKAAVERSKMIEKQLQKDKQVYRATHRLLLLGADNSGKSTIVKQMRIYHVNGYSEEECKQYKAVVYSNTIQ
SIIAIIRAMGRLKIDFGDSARADDARQLFVLAGAAEEGFMTAELAGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDL
DRIAQPNYIPTQQDVLRTRVKTSGIFETKFQVDKVNFHMFDVGAQRDERRKWIQCFNDVTAIIFVVDSSDYNRLQEALND
FKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTAS
GDGRHYCYPHFTCSVDTENARRIFNDCRDIIQRMHLRQYELL
;
A ? 
2 'polypeptide(L)' no no 
;MGSLLQSELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQ
DGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDN
QIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFF
PNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRV
SCLGVTDDGMAVATGSWDSFLKIWN
;
;MGSLLQSELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQ
DGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDN
QIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFF
PNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRV
SCLGVTDDGMAVATGSWDSFLKIWN
;
B ? 
3 'polypeptide(L)' no no MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFCAIL 
MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFCAIL G ? 
4 'polypeptide(L)' no no 
;MGNITADNSSMSCTIDHTIHQTLAPVVYVTVLVVGFPANCLSLYFGYLQIKARNELGVYLCNLTVADLFYICSLPFWLQY
VLQHDNWSHGDLSCQVCGILLYENIYISVGFLCCISVDRYLAVAHPFRFHQFRTLKAAVGVSVVIWAKELLTSIYFLMHE
EVIEDENQHRVCFEHYPIQAWQRAINYYRFLVGFLFPICLLLASYQGILRAVRRSHGTQKSRKDQIQRLVLSTVVIFLAC
FLPYHVLLLVRSVWEASCDFAKGVFNAYHFSLLLTSFNCVADPVLYCFVSETTHRDLARLRGACLAFLTCSRTGRAREA
;
;MGNITADNSSMSCTIDHTIHQTLAPVVYVTVLVVGFPANCLSLYFGYLQIKARNELGVYLCNLTVADLFYICSLPFWLQY
VLQHDNWSHGDLSCQVCGILLYENIYISVGFLCCISVDRYLAVAHPFRFHQFRTLKAAVGVSVVIWAKELLTSIYFLMHE
EVIEDENQHRVCFEHYPIQAWQRAINYYRFLVGFLFPICLLLASYQGILRAVRRSHGTQKSRKDQIQRLVLSTVVIFLAC
FLPYHVLLLVRSVWEASCDFAKGVFNAYHFSLLLTSFNCVADPVLYCFVSETTHRDLARLRGACLAFLTCSRTGRAREA
;
R ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   MET n 
1 3   GLY n 
1 4   CYS n 
1 5   THR n 
1 6   LEU n 
1 7   SER n 
1 8   ALA n 
1 9   GLU n 
1 10  ASP n 
1 11  LYS n 
1 12  ALA n 
1 13  ALA n 
1 14  VAL n 
1 15  GLU n 
1 16  ARG n 
1 17  SER n 
1 18  LYS n 
1 19  MET n 
1 20  ILE n 
1 21  GLU n 
1 22  LYS n 
1 23  GLN n 
1 24  LEU n 
1 25  GLN n 
1 26  LYS n 
1 27  ASP n 
1 28  LYS n 
1 29  GLN n 
1 30  VAL n 
1 31  TYR n 
1 32  ARG n 
1 33  ALA n 
1 34  THR n 
1 35  HIS n 
1 36  ARG n 
1 37  LEU n 
1 38  LEU n 
1 39  LEU n 
1 40  LEU n 
1 41  GLY n 
1 42  ALA n 
1 43  ASP n 
1 44  ASN n 
1 45  SER n 
1 46  GLY n 
1 47  LYS n 
1 48  SER n 
1 49  THR n 
1 50  ILE n 
1 51  VAL n 
1 52  LYS n 
1 53  GLN n 
1 54  MET n 
1 55  ARG n 
1 56  ILE n 
1 57  TYR n 
1 58  HIS n 
1 59  VAL n 
1 60  ASN n 
1 61  GLY n 
1 62  TYR n 
1 63  SER n 
1 64  GLU n 
1 65  GLU n 
1 66  GLU n 
1 67  CYS n 
1 68  LYS n 
1 69  GLN n 
1 70  TYR n 
1 71  LYS n 
1 72  ALA n 
1 73  VAL n 
1 74  VAL n 
1 75  TYR n 
1 76  SER n 
1 77  ASN n 
1 78  THR n 
1 79  ILE n 
1 80  GLN n 
1 81  SER n 
1 82  ILE n 
1 83  ILE n 
1 84  ALA n 
1 85  ILE n 
1 86  ILE n 
1 87  ARG n 
1 88  ALA n 
1 89  MET n 
1 90  GLY n 
1 91  ARG n 
1 92  LEU n 
1 93  LYS n 
1 94  ILE n 
1 95  ASP n 
1 96  PHE n 
1 97  GLY n 
1 98  ASP n 
1 99  SER n 
1 100 ALA n 
1 101 ARG n 
1 102 ALA n 
1 103 ASP n 
1 104 ASP n 
1 105 ALA n 
1 106 ARG n 
1 107 GLN n 
1 108 LEU n 
1 109 PHE n 
1 110 VAL n 
1 111 LEU n 
1 112 ALA n 
1 113 GLY n 
1 114 ALA n 
1 115 ALA n 
1 116 GLU n 
1 117 GLU n 
1 118 GLY n 
1 119 PHE n 
1 120 MET n 
1 121 THR n 
1 122 ALA n 
1 123 GLU n 
1 124 LEU n 
1 125 ALA n 
1 126 GLY n 
1 127 VAL n 
1 128 ILE n 
1 129 LYS n 
1 130 ARG n 
1 131 LEU n 
1 132 TRP n 
1 133 LYS n 
1 134 ASP n 
1 135 SER n 
1 136 GLY n 
1 137 VAL n 
1 138 GLN n 
1 139 ALA n 
1 140 CYS n 
1 141 PHE n 
1 142 ASN n 
1 143 ARG n 
1 144 SER n 
1 145 ARG n 
1 146 GLU n 
1 147 TYR n 
1 148 GLN n 
1 149 LEU n 
1 150 ASN n 
1 151 ASP n 
1 152 SER n 
1 153 ALA n 
1 154 ALA n 
1 155 TYR n 
1 156 TYR n 
1 157 LEU n 
1 158 ASN n 
1 159 ASP n 
1 160 LEU n 
1 161 ASP n 
1 162 ARG n 
1 163 ILE n 
1 164 ALA n 
1 165 GLN n 
1 166 PRO n 
1 167 ASN n 
1 168 TYR n 
1 169 ILE n 
1 170 PRO n 
1 171 THR n 
1 172 GLN n 
1 173 GLN n 
1 174 ASP n 
1 175 VAL n 
1 176 LEU n 
1 177 ARG n 
1 178 THR n 
1 179 ARG n 
1 180 VAL n 
1 181 LYS n 
1 182 THR n 
1 183 SER n 
1 184 GLY n 
1 185 ILE n 
1 186 PHE n 
1 187 GLU n 
1 188 THR n 
1 189 LYS n 
1 190 PHE n 
1 191 GLN n 
1 192 VAL n 
1 193 ASP n 
1 194 LYS n 
1 195 VAL n 
1 196 ASN n 
1 197 PHE n 
1 198 HIS n 
1 199 MET n 
1 200 PHE n 
1 201 ASP n 
1 202 VAL n 
1 203 GLY n 
1 204 ALA n 
1 205 GLN n 
1 206 ARG n 
1 207 ASP n 
1 208 GLU n 
1 209 ARG n 
1 210 ARG n 
1 211 LYS n 
1 212 TRP n 
1 213 ILE n 
1 214 GLN n 
1 215 CYS n 
1 216 PHE n 
1 217 ASN n 
1 218 ASP n 
1 219 VAL n 
1 220 THR n 
1 221 ALA n 
1 222 ILE n 
1 223 ILE n 
1 224 PHE n 
1 225 VAL n 
1 226 VAL n 
1 227 ASP n 
1 228 SER n 
1 229 SER n 
1 230 ASP n 
1 231 TYR n 
1 232 ASN n 
1 233 ARG n 
1 234 LEU n 
1 235 GLN n 
1 236 GLU n 
1 237 ALA n 
1 238 LEU n 
1 239 ASN n 
1 240 ASP n 
1 241 PHE n 
1 242 LYS n 
1 243 SER n 
1 244 ILE n 
1 245 TRP n 
1 246 ASN n 
1 247 ASN n 
1 248 ARG n 
1 249 TRP n 
1 250 LEU n 
1 251 ARG n 
1 252 THR n 
1 253 ILE n 
1 254 SER n 
1 255 VAL n 
1 256 ILE n 
1 257 LEU n 
1 258 PHE n 
1 259 LEU n 
1 260 ASN n 
1 261 LYS n 
1 262 GLN n 
1 263 ASP n 
1 264 LEU n 
1 265 LEU n 
1 266 ALA n 
1 267 GLU n 
1 268 LYS n 
1 269 VAL n 
1 270 LEU n 
1 271 ALA n 
1 272 GLY n 
1 273 LYS n 
1 274 SER n 
1 275 LYS n 
1 276 ILE n 
1 277 GLU n 
1 278 ASP n 
1 279 TYR n 
1 280 PHE n 
1 281 PRO n 
1 282 GLU n 
1 283 PHE n 
1 284 ALA n 
1 285 ARG n 
1 286 TYR n 
1 287 THR n 
1 288 THR n 
1 289 PRO n 
1 290 GLU n 
1 291 ASP n 
1 292 ALA n 
1 293 THR n 
1 294 PRO n 
1 295 GLU n 
1 296 PRO n 
1 297 GLY n 
1 298 GLU n 
1 299 ASP n 
1 300 PRO n 
1 301 ARG n 
1 302 VAL n 
1 303 THR n 
1 304 ARG n 
1 305 ALA n 
1 306 LYS n 
1 307 TYR n 
1 308 PHE n 
1 309 ILE n 
1 310 ARG n 
1 311 ASP n 
1 312 GLU n 
1 313 PHE n 
1 314 LEU n 
1 315 ARG n 
1 316 ILE n 
1 317 SER n 
1 318 THR n 
1 319 ALA n 
1 320 SER n 
1 321 GLY n 
1 322 ASP n 
1 323 GLY n 
1 324 ARG n 
1 325 HIS n 
1 326 TYR n 
1 327 CYS n 
1 328 TYR n 
1 329 PRO n 
1 330 HIS n 
1 331 PHE n 
1 332 THR n 
1 333 CYS n 
1 334 SER n 
1 335 VAL n 
1 336 ASP n 
1 337 THR n 
1 338 GLU n 
1 339 ASN n 
1 340 ALA n 
1 341 ARG n 
1 342 ARG n 
1 343 ILE n 
1 344 PHE n 
1 345 ASN n 
1 346 ASP n 
1 347 CYS n 
1 348 ARG n 
1 349 ASP n 
1 350 ILE n 
1 351 ILE n 
1 352 GLN n 
1 353 ARG n 
1 354 MET n 
1 355 HIS n 
1 356 LEU n 
1 357 ARG n 
1 358 GLN n 
1 359 TYR n 
1 360 GLU n 
1 361 LEU n 
1 362 LEU n 
2 1   MET n 
2 2   GLY n 
2 3   SER n 
2 4   LEU n 
2 5   LEU n 
2 6   GLN n 
2 7   SER n 
2 8   GLU n 
2 9   LEU n 
2 10  ASP n 
2 11  GLN n 
2 12  LEU n 
2 13  ARG n 
2 14  GLN n 
2 15  GLU n 
2 16  ALA n 
2 17  GLU n 
2 18  GLN n 
2 19  LEU n 
2 20  LYS n 
2 21  ASN n 
2 22  GLN n 
2 23  ILE n 
2 24  ARG n 
2 25  ASP n 
2 26  ALA n 
2 27  ARG n 
2 28  LYS n 
2 29  ALA n 
2 30  CYS n 
2 31  ALA n 
2 32  ASP n 
2 33  ALA n 
2 34  THR n 
2 35  LEU n 
2 36  SER n 
2 37  GLN n 
2 38  ILE n 
2 39  THR n 
2 40  ASN n 
2 41  ASN n 
2 42  ILE n 
2 43  ASP n 
2 44  PRO n 
2 45  VAL n 
2 46  GLY n 
2 47  ARG n 
2 48  ILE n 
2 49  GLN n 
2 50  MET n 
2 51  ARG n 
2 52  THR n 
2 53  ARG n 
2 54  ARG n 
2 55  THR n 
2 56  LEU n 
2 57  ARG n 
2 58  GLY n 
2 59  HIS n 
2 60  LEU n 
2 61  ALA n 
2 62  LYS n 
2 63  ILE n 
2 64  TYR n 
2 65  ALA n 
2 66  MET n 
2 67  HIS n 
2 68  TRP n 
2 69  GLY n 
2 70  THR n 
2 71  ASP n 
2 72  SER n 
2 73  ARG n 
2 74  LEU n 
2 75  LEU n 
2 76  VAL n 
2 77  SER n 
2 78  ALA n 
2 79  SER n 
2 80  GLN n 
2 81  ASP n 
2 82  GLY n 
2 83  LYS n 
2 84  LEU n 
2 85  ILE n 
2 86  ILE n 
2 87  TRP n 
2 88  ASP n 
2 89  SER n 
2 90  TYR n 
2 91  THR n 
2 92  THR n 
2 93  ASN n 
2 94  LYS n 
2 95  VAL n 
2 96  HIS n 
2 97  ALA n 
2 98  ILE n 
2 99  PRO n 
2 100 LEU n 
2 101 ARG n 
2 102 SER n 
2 103 SER n 
2 104 TRP n 
2 105 VAL n 
2 106 MET n 
2 107 THR n 
2 108 CYS n 
2 109 ALA n 
2 110 TYR n 
2 111 ALA n 
2 112 PRO n 
2 113 SER n 
2 114 GLY n 
2 115 ASN n 
2 116 TYR n 
2 117 VAL n 
2 118 ALA n 
2 119 CYS n 
2 120 GLY n 
2 121 GLY n 
2 122 LEU n 
2 123 ASP n 
2 124 ASN n 
2 125 ILE n 
2 126 CYS n 
2 127 SER n 
2 128 ILE n 
2 129 TYR n 
2 130 ASN n 
2 131 LEU n 
2 132 LYS n 
2 133 THR n 
2 134 ARG n 
2 135 GLU n 
2 136 GLY n 
2 137 ASN n 
2 138 VAL n 
2 139 ARG n 
2 140 VAL n 
2 141 SER n 
2 142 ARG n 
2 143 GLU n 
2 144 LEU n 
2 145 ALA n 
2 146 GLY n 
2 147 HIS n 
2 148 THR n 
2 149 GLY n 
2 150 TYR n 
2 151 LEU n 
2 152 SER n 
2 153 CYS n 
2 154 CYS n 
2 155 ARG n 
2 156 PHE n 
2 157 LEU n 
2 158 ASP n 
2 159 ASP n 
2 160 ASN n 
2 161 GLN n 
2 162 ILE n 
2 163 VAL n 
2 164 THR n 
2 165 SER n 
2 166 SER n 
2 167 GLY n 
2 168 ASP n 
2 169 THR n 
2 170 THR n 
2 171 CYS n 
2 172 ALA n 
2 173 LEU n 
2 174 TRP n 
2 175 ASP n 
2 176 ILE n 
2 177 GLU n 
2 178 THR n 
2 179 GLY n 
2 180 GLN n 
2 181 GLN n 
2 182 THR n 
2 183 THR n 
2 184 THR n 
2 185 PHE n 
2 186 THR n 
2 187 GLY n 
2 188 HIS n 
2 189 THR n 
2 190 GLY n 
2 191 ASP n 
2 192 VAL n 
2 193 MET n 
2 194 SER n 
2 195 LEU n 
2 196 SER n 
2 197 LEU n 
2 198 ALA n 
2 199 PRO n 
2 200 ASP n 
2 201 THR n 
2 202 ARG n 
2 203 LEU n 
2 204 PHE n 
2 205 VAL n 
2 206 SER n 
2 207 GLY n 
2 208 ALA n 
2 209 CYS n 
2 210 ASP n 
2 211 ALA n 
2 212 SER n 
2 213 ALA n 
2 214 LYS n 
2 215 LEU n 
2 216 TRP n 
2 217 ASP n 
2 218 VAL n 
2 219 ARG n 
2 220 GLU n 
2 221 GLY n 
2 222 MET n 
2 223 CYS n 
2 224 ARG n 
2 225 GLN n 
2 226 THR n 
2 227 PHE n 
2 228 THR n 
2 229 GLY n 
2 230 HIS n 
2 231 GLU n 
2 232 SER n 
2 233 ASP n 
2 234 ILE n 
2 235 ASN n 
2 236 ALA n 
2 237 ILE n 
2 238 CYS n 
2 239 PHE n 
2 240 PHE n 
2 241 PRO n 
2 242 ASN n 
2 243 GLY n 
2 244 ASN n 
2 245 ALA n 
2 246 PHE n 
2 247 ALA n 
2 248 THR n 
2 249 GLY n 
2 250 SER n 
2 251 ASP n 
2 252 ASP n 
2 253 ALA n 
2 254 THR n 
2 255 CYS n 
2 256 ARG n 
2 257 LEU n 
2 258 PHE n 
2 259 ASP n 
2 260 LEU n 
2 261 ARG n 
2 262 ALA n 
2 263 ASP n 
2 264 GLN n 
2 265 GLU n 
2 266 LEU n 
2 267 MET n 
2 268 THR n 
2 269 TYR n 
2 270 SER n 
2 271 HIS n 
2 272 ASP n 
2 273 ASN n 
2 274 ILE n 
2 275 ILE n 
2 276 CYS n 
2 277 GLY n 
2 278 ILE n 
2 279 THR n 
2 280 SER n 
2 281 VAL n 
2 282 SER n 
2 283 PHE n 
2 284 SER n 
2 285 LYS n 
2 286 SER n 
2 287 GLY n 
2 288 ARG n 
2 289 LEU n 
2 290 LEU n 
2 291 LEU n 
2 292 ALA n 
2 293 GLY n 
2 294 TYR n 
2 295 ASP n 
2 296 ASP n 
2 297 PHE n 
2 298 ASN n 
2 299 CYS n 
2 300 ASN n 
2 301 VAL n 
2 302 TRP n 
2 303 ASP n 
2 304 ALA n 
2 305 LEU n 
2 306 LYS n 
2 307 ALA n 
2 308 ASP n 
2 309 ARG n 
2 310 ALA n 
2 311 GLY n 
2 312 VAL n 
2 313 LEU n 
2 314 ALA n 
2 315 GLY n 
2 316 HIS n 
2 317 ASP n 
2 318 ASN n 
2 319 ARG n 
2 320 VAL n 
2 321 SER n 
2 322 CYS n 
2 323 LEU n 
2 324 GLY n 
2 325 VAL n 
2 326 THR n 
2 327 ASP n 
2 328 ASP n 
2 329 GLY n 
2 330 MET n 
2 331 ALA n 
2 332 VAL n 
2 333 ALA n 
2 334 THR n 
2 335 GLY n 
2 336 SER n 
2 337 TRP n 
2 338 ASP n 
2 339 SER n 
2 340 PHE n 
2 341 LEU n 
2 342 LYS n 
2 343 ILE n 
2 344 TRP n 
2 345 ASN n 
3 1   MET n 
3 2   ALA n 
3 3   SER n 
3 4   ASN n 
3 5   ASN n 
3 6   THR n 
3 7   ALA n 
3 8   SER n 
3 9   ILE n 
3 10  ALA n 
3 11  GLN n 
3 12  ALA n 
3 13  ARG n 
3 14  LYS n 
3 15  LEU n 
3 16  VAL n 
3 17  GLU n 
3 18  GLN n 
3 19  LEU n 
3 20  LYS n 
3 21  MET n 
3 22  GLU n 
3 23  ALA n 
3 24  ASN n 
3 25  ILE n 
3 26  ASP n 
3 27  ARG n 
3 28  ILE n 
3 29  LYS n 
3 30  VAL n 
3 31  SER n 
3 32  LYS n 
3 33  ALA n 
3 34  ALA n 
3 35  ALA n 
3 36  ASP n 
3 37  LEU n 
3 38  MET n 
3 39  ALA n 
3 40  TYR n 
3 41  CYS n 
3 42  GLU n 
3 43  ALA n 
3 44  HIS n 
3 45  ALA n 
3 46  LYS n 
3 47  GLU n 
3 48  ASP n 
3 49  PRO n 
3 50  LEU n 
3 51  LEU n 
3 52  THR n 
3 53  PRO n 
3 54  VAL n 
3 55  PRO n 
3 56  ALA n 
3 57  SER n 
3 58  GLU n 
3 59  ASN n 
3 60  PRO n 
3 61  PHE n 
3 62  ARG n 
3 63  GLU n 
3 64  LYS n 
3 65  LYS n 
3 66  PHE n 
3 67  PHE n 
3 68  CYS n 
3 69  ALA n 
3 70  ILE n 
3 71  LEU n 
4 1   MET n 
4 2   GLY n 
4 3   ASN n 
4 4   ILE n 
4 5   THR n 
4 6   ALA n 
4 7   ASP n 
4 8   ASN n 
4 9   SER n 
4 10  SER n 
4 11  MET n 
4 12  SER n 
4 13  CYS n 
4 14  THR n 
4 15  ILE n 
4 16  ASP n 
4 17  HIS n 
4 18  THR n 
4 19  ILE n 
4 20  HIS n 
4 21  GLN n 
4 22  THR n 
4 23  LEU n 
4 24  ALA n 
4 25  PRO n 
4 26  VAL n 
4 27  VAL n 
4 28  TYR n 
4 29  VAL n 
4 30  THR n 
4 31  VAL n 
4 32  LEU n 
4 33  VAL n 
4 34  VAL n 
4 35  GLY n 
4 36  PHE n 
4 37  PRO n 
4 38  ALA n 
4 39  ASN n 
4 40  CYS n 
4 41  LEU n 
4 42  SER n 
4 43  LEU n 
4 44  TYR n 
4 45  PHE n 
4 46  GLY n 
4 47  TYR n 
4 48  LEU n 
4 49  GLN n 
4 50  ILE n 
4 51  LYS n 
4 52  ALA n 
4 53  ARG n 
4 54  ASN n 
4 55  GLU n 
4 56  LEU n 
4 57  GLY n 
4 58  VAL n 
4 59  TYR n 
4 60  LEU n 
4 61  CYS n 
4 62  ASN n 
4 63  LEU n 
4 64  THR n 
4 65  VAL n 
4 66  ALA n 
4 67  ASP n 
4 68  LEU n 
4 69  PHE n 
4 70  TYR n 
4 71  ILE n 
4 72  CYS n 
4 73  SER n 
4 74  LEU n 
4 75  PRO n 
4 76  PHE n 
4 77  TRP n 
4 78  LEU n 
4 79  GLN n 
4 80  TYR n 
4 81  VAL n 
4 82  LEU n 
4 83  GLN n 
4 84  HIS n 
4 85  ASP n 
4 86  ASN n 
4 87  TRP n 
4 88  SER n 
4 89  HIS n 
4 90  GLY n 
4 91  ASP n 
4 92  LEU n 
4 93  SER n 
4 94  CYS n 
4 95  GLN n 
4 96  VAL n 
4 97  CYS n 
4 98  GLY n 
4 99  ILE n 
4 100 LEU n 
4 101 LEU n 
4 102 TYR n 
4 103 GLU n 
4 104 ASN n 
4 105 ILE n 
4 106 TYR n 
4 107 ILE n 
4 108 SER n 
4 109 VAL n 
4 110 GLY n 
4 111 PHE n 
4 112 LEU n 
4 113 CYS n 
4 114 CYS n 
4 115 ILE n 
4 116 SER n 
4 117 VAL n 
4 118 ASP n 
4 119 ARG n 
4 120 TYR n 
4 121 LEU n 
4 122 ALA n 
4 123 VAL n 
4 124 ALA n 
4 125 HIS n 
4 126 PRO n 
4 127 PHE n 
4 128 ARG n 
4 129 PHE n 
4 130 HIS n 
4 131 GLN n 
4 132 PHE n 
4 133 ARG n 
4 134 THR n 
4 135 LEU n 
4 136 LYS n 
4 137 ALA n 
4 138 ALA n 
4 139 VAL n 
4 140 GLY n 
4 141 VAL n 
4 142 SER n 
4 143 VAL n 
4 144 VAL n 
4 145 ILE n 
4 146 TRP n 
4 147 ALA n 
4 148 LYS n 
4 149 GLU n 
4 150 LEU n 
4 151 LEU n 
4 152 THR n 
4 153 SER n 
4 154 ILE n 
4 155 TYR n 
4 156 PHE n 
4 157 LEU n 
4 158 MET n 
4 159 HIS n 
4 160 GLU n 
4 161 GLU n 
4 162 VAL n 
4 163 ILE n 
4 164 GLU n 
4 165 ASP n 
4 166 GLU n 
4 167 ASN n 
4 168 GLN n 
4 169 HIS n 
4 170 ARG n 
4 171 VAL n 
4 172 CYS n 
4 173 PHE n 
4 174 GLU n 
4 175 HIS n 
4 176 TYR n 
4 177 PRO n 
4 178 ILE n 
4 179 GLN n 
4 180 ALA n 
4 181 TRP n 
4 182 GLN n 
4 183 ARG n 
4 184 ALA n 
4 185 ILE n 
4 186 ASN n 
4 187 TYR n 
4 188 TYR n 
4 189 ARG n 
4 190 PHE n 
4 191 LEU n 
4 192 VAL n 
4 193 GLY n 
4 194 PHE n 
4 195 LEU n 
4 196 PHE n 
4 197 PRO n 
4 198 ILE n 
4 199 CYS n 
4 200 LEU n 
4 201 LEU n 
4 202 LEU n 
4 203 ALA n 
4 204 SER n 
4 205 TYR n 
4 206 GLN n 
4 207 GLY n 
4 208 ILE n 
4 209 LEU n 
4 210 ARG n 
4 211 ALA n 
4 212 VAL n 
4 213 ARG n 
4 214 ARG n 
4 215 SER n 
4 216 HIS n 
4 217 GLY n 
4 218 THR n 
4 219 GLN n 
4 220 LYS n 
4 221 SER n 
4 222 ARG n 
4 223 LYS n 
4 224 ASP n 
4 225 GLN n 
4 226 ILE n 
4 227 GLN n 
4 228 ARG n 
4 229 LEU n 
4 230 VAL n 
4 231 LEU n 
4 232 SER n 
4 233 THR n 
4 234 VAL n 
4 235 VAL n 
4 236 ILE n 
4 237 PHE n 
4 238 LEU n 
4 239 ALA n 
4 240 CYS n 
4 241 PHE n 
4 242 LEU n 
4 243 PRO n 
4 244 TYR n 
4 245 HIS n 
4 246 VAL n 
4 247 LEU n 
4 248 LEU n 
4 249 LEU n 
4 250 VAL n 
4 251 ARG n 
4 252 SER n 
4 253 VAL n 
4 254 TRP n 
4 255 GLU n 
4 256 ALA n 
4 257 SER n 
4 258 CYS n 
4 259 ASP n 
4 260 PHE n 
4 261 ALA n 
4 262 LYS n 
4 263 GLY n 
4 264 VAL n 
4 265 PHE n 
4 266 ASN n 
4 267 ALA n 
4 268 TYR n 
4 269 HIS n 
4 270 PHE n 
4 271 SER n 
4 272 LEU n 
4 273 LEU n 
4 274 LEU n 
4 275 THR n 
4 276 SER n 
4 277 PHE n 
4 278 ASN n 
4 279 CYS n 
4 280 VAL n 
4 281 ALA n 
4 282 ASP n 
4 283 PRO n 
4 284 VAL n 
4 285 LEU n 
4 286 TYR n 
4 287 CYS n 
4 288 PHE n 
4 289 VAL n 
4 290 SER n 
4 291 GLU n 
4 292 THR n 
4 293 THR n 
4 294 HIS n 
4 295 ARG n 
4 296 ASP n 
4 297 LEU n 
4 298 ALA n 
4 299 ARG n 
4 300 LEU n 
4 301 ARG n 
4 302 GLY n 
4 303 ALA n 
4 304 CYS n 
4 305 LEU n 
4 306 ALA n 
4 307 PHE n 
4 308 LEU n 
4 309 THR n 
4 310 CYS n 
4 311 SER n 
4 312 ARG n 
4 313 THR n 
4 314 GLY n 
4 315 ARG n 
4 316 ALA n 
4 317 ARG n 
4 318 GLU n 
4 319 ALA n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 362 human ? ?             ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Spodoptera frugiperda' 7108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 345 human ? GNB1          ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Spodoptera frugiperda' 7108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
3 1 sample 'Biological sequence' 1 71  human ? GNG2          ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Spodoptera frugiperda' 7108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
4 1 sample 'Biological sequence' 1 319 human ? 'GPR68, OGR1' ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Spodoptera frugiperda' 7108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   0   ?   ?   ?   A . n 
A 1 2   MET 2   1   ?   ?   ?   A . n 
A 1 3   GLY 3   2   ?   ?   ?   A . n 
A 1 4   CYS 4   3   ?   ?   ?   A . n 
A 1 5   THR 5   4   ?   ?   ?   A . n 
A 1 6   LEU 6   5   5   LEU LEU A . n 
A 1 7   SER 7   6   6   SER SER A . n 
A 1 8   ALA 8   7   7   ALA ALA A . n 
A 1 9   GLU 9   8   8   GLU GLU A . n 
A 1 10  ASP 10  9   9   ASP ASP A . n 
A 1 11  LYS 11  10  10  LYS LYS A . n 
A 1 12  ALA 12  11  11  ALA ALA A . n 
A 1 13  ALA 13  12  12  ALA ALA A . n 
A 1 14  VAL 14  13  13  VAL VAL A . n 
A 1 15  GLU 15  14  14  GLU GLU A . n 
A 1 16  ARG 16  15  15  ARG ARG A . n 
A 1 17  SER 17  16  16  SER SER A . n 
A 1 18  LYS 18  17  17  LYS LYS A . n 
A 1 19  MET 19  18  18  MET MET A . n 
A 1 20  ILE 20  26  26  ILE ILE A . n 
A 1 21  GLU 21  27  27  GLU GLU A . n 
A 1 22  LYS 22  28  28  LYS LYS A . n 
A 1 23  GLN 23  29  29  GLN GLN A . n 
A 1 24  LEU 24  30  30  LEU LEU A . n 
A 1 25  GLN 25  31  31  GLN GLN A . n 
A 1 26  LYS 26  32  32  LYS LYS A . n 
A 1 27  ASP 27  33  33  ASP ASP A . n 
A 1 28  LYS 28  34  34  LYS LYS A . n 
A 1 29  GLN 29  35  35  GLN GLN A . n 
A 1 30  VAL 30  36  36  VAL VAL A . n 
A 1 31  TYR 31  37  37  TYR TYR A . n 
A 1 32  ARG 32  38  38  ARG ARG A . n 
A 1 33  ALA 33  39  39  ALA ALA A . n 
A 1 34  THR 34  40  40  THR THR A . n 
A 1 35  HIS 35  41  41  HIS HIS A . n 
A 1 36  ARG 36  42  42  ARG ARG A . n 
A 1 37  LEU 37  43  43  LEU LEU A . n 
A 1 38  LEU 38  44  44  LEU LEU A . n 
A 1 39  LEU 39  45  45  LEU LEU A . n 
A 1 40  LEU 40  46  46  LEU LEU A . n 
A 1 41  GLY 41  47  47  GLY GLY A . n 
A 1 42  ALA 42  48  48  ALA ALA A . n 
A 1 43  ASP 43  49  49  ASP ASP A . n 
A 1 44  ASN 44  50  50  ASN ASN A . n 
A 1 45  SER 45  51  51  SER SER A . n 
A 1 46  GLY 46  52  52  GLY GLY A . n 
A 1 47  LYS 47  53  53  LYS LYS A . n 
A 1 48  SER 48  54  54  SER SER A . n 
A 1 49  THR 49  55  55  THR THR A . n 
A 1 50  ILE 50  56  56  ILE ILE A . n 
A 1 51  VAL 51  57  57  VAL VAL A . n 
A 1 52  LYS 52  58  58  LYS LYS A . n 
A 1 53  GLN 53  59  59  GLN GLN A . n 
A 1 54  MET 54  60  60  MET MET A . n 
A 1 55  ARG 55  61  61  ARG ARG A . n 
A 1 56  ILE 56  62  62  ILE ILE A . n 
A 1 57  TYR 57  63  63  TYR TYR A . n 
A 1 58  HIS 58  64  64  HIS HIS A . n 
A 1 59  VAL 59  91  ?   ?   ?   A . n 
A 1 60  ASN 60  92  ?   ?   ?   A . n 
A 1 61  GLY 61  93  ?   ?   ?   A . n 
A 1 62  TYR 62  94  ?   ?   ?   A . n 
A 1 63  SER 63  95  ?   ?   ?   A . n 
A 1 64  GLU 64  96  ?   ?   ?   A . n 
A 1 65  GLU 65  97  ?   ?   ?   A . n 
A 1 66  GLU 66  98  ?   ?   ?   A . n 
A 1 67  CYS 67  99  ?   ?   ?   A . n 
A 1 68  LYS 68  100 ?   ?   ?   A . n 
A 1 69  GLN 69  101 ?   ?   ?   A . n 
A 1 70  TYR 70  102 ?   ?   ?   A . n 
A 1 71  LYS 71  103 ?   ?   ?   A . n 
A 1 72  ALA 72  104 ?   ?   ?   A . n 
A 1 73  VAL 73  105 ?   ?   ?   A . n 
A 1 74  VAL 74  106 ?   ?   ?   A . n 
A 1 75  TYR 75  107 ?   ?   ?   A . n 
A 1 76  SER 76  108 ?   ?   ?   A . n 
A 1 77  ASN 77  109 ?   ?   ?   A . n 
A 1 78  THR 78  110 ?   ?   ?   A . n 
A 1 79  ILE 79  111 ?   ?   ?   A . n 
A 1 80  GLN 80  112 ?   ?   ?   A . n 
A 1 81  SER 81  113 ?   ?   ?   A . n 
A 1 82  ILE 82  114 ?   ?   ?   A . n 
A 1 83  ILE 83  115 ?   ?   ?   A . n 
A 1 84  ALA 84  116 ?   ?   ?   A . n 
A 1 85  ILE 85  117 ?   ?   ?   A . n 
A 1 86  ILE 86  118 ?   ?   ?   A . n 
A 1 87  ARG 87  119 ?   ?   ?   A . n 
A 1 88  ALA 88  120 ?   ?   ?   A . n 
A 1 89  MET 89  121 ?   ?   ?   A . n 
A 1 90  GLY 90  122 ?   ?   ?   A . n 
A 1 91  ARG 91  123 ?   ?   ?   A . n 
A 1 92  LEU 92  124 ?   ?   ?   A . n 
A 1 93  LYS 93  125 ?   ?   ?   A . n 
A 1 94  ILE 94  126 ?   ?   ?   A . n 
A 1 95  ASP 95  127 ?   ?   ?   A . n 
A 1 96  PHE 96  128 ?   ?   ?   A . n 
A 1 97  GLY 97  129 ?   ?   ?   A . n 
A 1 98  ASP 98  130 ?   ?   ?   A . n 
A 1 99  SER 99  131 ?   ?   ?   A . n 
A 1 100 ALA 100 132 ?   ?   ?   A . n 
A 1 101 ARG 101 133 ?   ?   ?   A . n 
A 1 102 ALA 102 134 ?   ?   ?   A . n 
A 1 103 ASP 103 135 ?   ?   ?   A . n 
A 1 104 ASP 104 136 ?   ?   ?   A . n 
A 1 105 ALA 105 137 ?   ?   ?   A . n 
A 1 106 ARG 106 138 ?   ?   ?   A . n 
A 1 107 GLN 107 139 ?   ?   ?   A . n 
A 1 108 LEU 108 140 ?   ?   ?   A . n 
A 1 109 PHE 109 141 ?   ?   ?   A . n 
A 1 110 VAL 110 142 ?   ?   ?   A . n 
A 1 111 LEU 111 143 ?   ?   ?   A . n 
A 1 112 ALA 112 144 ?   ?   ?   A . n 
A 1 113 GLY 113 145 ?   ?   ?   A . n 
A 1 114 ALA 114 146 ?   ?   ?   A . n 
A 1 115 ALA 115 147 ?   ?   ?   A . n 
A 1 116 GLU 116 148 ?   ?   ?   A . n 
A 1 117 GLU 117 149 ?   ?   ?   A . n 
A 1 118 GLY 118 150 ?   ?   ?   A . n 
A 1 119 PHE 119 151 ?   ?   ?   A . n 
A 1 120 MET 120 152 ?   ?   ?   A . n 
A 1 121 THR 121 153 ?   ?   ?   A . n 
A 1 122 ALA 122 154 ?   ?   ?   A . n 
A 1 123 GLU 123 155 ?   ?   ?   A . n 
A 1 124 LEU 124 156 ?   ?   ?   A . n 
A 1 125 ALA 125 157 ?   ?   ?   A . n 
A 1 126 GLY 126 158 ?   ?   ?   A . n 
A 1 127 VAL 127 159 ?   ?   ?   A . n 
A 1 128 ILE 128 160 ?   ?   ?   A . n 
A 1 129 LYS 129 161 ?   ?   ?   A . n 
A 1 130 ARG 130 162 ?   ?   ?   A . n 
A 1 131 LEU 131 163 ?   ?   ?   A . n 
A 1 132 TRP 132 164 ?   ?   ?   A . n 
A 1 133 LYS 133 165 ?   ?   ?   A . n 
A 1 134 ASP 134 166 ?   ?   ?   A . n 
A 1 135 SER 135 167 ?   ?   ?   A . n 
A 1 136 GLY 136 168 ?   ?   ?   A . n 
A 1 137 VAL 137 169 ?   ?   ?   A . n 
A 1 138 GLN 138 170 ?   ?   ?   A . n 
A 1 139 ALA 139 171 ?   ?   ?   A . n 
A 1 140 CYS 140 172 ?   ?   ?   A . n 
A 1 141 PHE 141 173 ?   ?   ?   A . n 
A 1 142 ASN 142 174 ?   ?   ?   A . n 
A 1 143 ARG 143 175 ?   ?   ?   A . n 
A 1 144 SER 144 176 ?   ?   ?   A . n 
A 1 145 ARG 145 177 ?   ?   ?   A . n 
A 1 146 GLU 146 178 ?   ?   ?   A . n 
A 1 147 TYR 147 179 ?   ?   ?   A . n 
A 1 148 GLN 148 180 ?   ?   ?   A . n 
A 1 149 LEU 149 181 ?   ?   ?   A . n 
A 1 150 ASN 150 182 ?   ?   ?   A . n 
A 1 151 ASP 151 183 ?   ?   ?   A . n 
A 1 152 SER 152 184 ?   ?   ?   A . n 
A 1 153 ALA 153 185 ?   ?   ?   A . n 
A 1 154 ALA 154 186 ?   ?   ?   A . n 
A 1 155 TYR 155 187 ?   ?   ?   A . n 
A 1 156 TYR 156 188 ?   ?   ?   A . n 
A 1 157 LEU 157 189 ?   ?   ?   A . n 
A 1 158 ASN 158 190 ?   ?   ?   A . n 
A 1 159 ASP 159 191 ?   ?   ?   A . n 
A 1 160 LEU 160 192 ?   ?   ?   A . n 
A 1 161 ASP 161 193 ?   ?   ?   A . n 
A 1 162 ARG 162 194 ?   ?   ?   A . n 
A 1 163 ILE 163 195 ?   ?   ?   A . n 
A 1 164 ALA 164 196 ?   ?   ?   A . n 
A 1 165 GLN 165 197 ?   ?   ?   A . n 
A 1 166 PRO 166 198 ?   ?   ?   A . n 
A 1 167 ASN 167 199 ?   ?   ?   A . n 
A 1 168 TYR 168 200 ?   ?   ?   A . n 
A 1 169 ILE 169 201 ?   ?   ?   A . n 
A 1 170 PRO 170 202 ?   ?   ?   A . n 
A 1 171 THR 171 203 ?   ?   ?   A . n 
A 1 172 GLN 172 204 ?   ?   ?   A . n 
A 1 173 GLN 173 205 ?   ?   ?   A . n 
A 1 174 ASP 174 206 ?   ?   ?   A . n 
A 1 175 VAL 175 207 ?   ?   ?   A . n 
A 1 176 LEU 176 208 ?   ?   ?   A . n 
A 1 177 ARG 177 209 ?   ?   ?   A . n 
A 1 178 THR 178 210 ?   ?   ?   A . n 
A 1 179 ARG 179 211 ?   ?   ?   A . n 
A 1 180 VAL 180 212 212 VAL VAL A . n 
A 1 181 LYS 181 213 213 LYS LYS A . n 
A 1 182 THR 182 214 214 THR THR A . n 
A 1 183 SER 183 215 215 SER SER A . n 
A 1 184 GLY 184 216 216 GLY GLY A . n 
A 1 185 ILE 185 217 217 ILE ILE A . n 
A 1 186 PHE 186 218 218 PHE PHE A . n 
A 1 187 GLU 187 219 219 GLU GLU A . n 
A 1 188 THR 188 220 220 THR THR A . n 
A 1 189 LYS 189 221 221 LYS LYS A . n 
A 1 190 PHE 190 222 222 PHE PHE A . n 
A 1 191 GLN 191 223 223 GLN GLN A . n 
A 1 192 VAL 192 224 224 VAL VAL A . n 
A 1 193 ASP 193 225 225 ASP ASP A . n 
A 1 194 LYS 194 226 226 LYS LYS A . n 
A 1 195 VAL 195 227 227 VAL VAL A . n 
A 1 196 ASN 196 228 228 ASN ASN A . n 
A 1 197 PHE 197 229 229 PHE PHE A . n 
A 1 198 HIS 198 230 230 HIS HIS A . n 
A 1 199 MET 199 231 231 MET MET A . n 
A 1 200 PHE 200 232 232 PHE PHE A . n 
A 1 201 ASP 201 233 233 ASP ASP A . n 
A 1 202 VAL 202 234 234 VAL VAL A . n 
A 1 203 GLY 203 235 235 GLY GLY A . n 
A 1 204 ALA 204 236 236 ALA ALA A . n 
A 1 205 GLN 205 237 237 GLN GLN A . n 
A 1 206 ARG 206 238 238 ARG ARG A . n 
A 1 207 ASP 207 239 239 ASP ASP A . n 
A 1 208 GLU 208 240 240 GLU GLU A . n 
A 1 209 ARG 209 241 241 ARG ARG A . n 
A 1 210 ARG 210 242 242 ARG ARG A . n 
A 1 211 LYS 211 243 243 LYS LYS A . n 
A 1 212 TRP 212 244 244 TRP TRP A . n 
A 1 213 ILE 213 245 245 ILE ILE A . n 
A 1 214 GLN 214 246 246 GLN GLN A . n 
A 1 215 CYS 215 247 247 CYS CYS A . n 
A 1 216 PHE 216 248 248 PHE PHE A . n 
A 1 217 ASN 217 249 249 ASN ASN A . n 
A 1 218 ASP 218 250 250 ASP ASP A . n 
A 1 219 VAL 219 251 251 VAL VAL A . n 
A 1 220 THR 220 252 252 THR THR A . n 
A 1 221 ALA 221 253 253 ALA ALA A . n 
A 1 222 ILE 222 254 254 ILE ILE A . n 
A 1 223 ILE 223 255 255 ILE ILE A . n 
A 1 224 PHE 224 256 256 PHE PHE A . n 
A 1 225 VAL 225 257 257 VAL VAL A . n 
A 1 226 VAL 226 258 258 VAL VAL A . n 
A 1 227 ASP 227 259 259 ASP ASP A . n 
A 1 228 SER 228 260 260 SER SER A . n 
A 1 229 SER 229 261 261 SER SER A . n 
A 1 230 ASP 230 262 262 ASP ASP A . n 
A 1 231 TYR 231 263 263 TYR TYR A . n 
A 1 232 ASN 232 264 264 ASN ALA A . n 
A 1 233 ARG 233 265 265 ARG ARG A . n 
A 1 234 LEU 234 266 266 LEU LEU A . n 
A 1 235 GLN 235 267 267 GLN GLN A . n 
A 1 236 GLU 236 268 268 GLU GLU A . n 
A 1 237 ALA 237 269 269 ALA ALA A . n 
A 1 238 LEU 238 270 270 LEU LEU A . n 
A 1 239 ASN 239 271 271 ASN ASN A . n 
A 1 240 ASP 240 272 272 ASP ASP A . n 
A 1 241 PHE 241 273 273 PHE PHE A . n 
A 1 242 LYS 242 274 274 LYS LYS A . n 
A 1 243 SER 243 275 275 SER SER A . n 
A 1 244 ILE 244 276 276 ILE ILE A . n 
A 1 245 TRP 245 277 277 TRP TRP A . n 
A 1 246 ASN 246 278 278 ASN ASN A . n 
A 1 247 ASN 247 279 279 ASN ASN A . n 
A 1 248 ARG 248 280 280 ARG ARG A . n 
A 1 249 TRP 249 281 281 TRP TRP A . n 
A 1 250 LEU 250 282 282 LEU LEU A . n 
A 1 251 ARG 251 283 283 ARG ARG A . n 
A 1 252 THR 252 284 284 THR THR A . n 
A 1 253 ILE 253 285 285 ILE ILE A . n 
A 1 254 SER 254 286 286 SER SER A . n 
A 1 255 VAL 255 287 287 VAL VAL A . n 
A 1 256 ILE 256 288 288 ILE ILE A . n 
A 1 257 LEU 257 289 289 LEU LEU A . n 
A 1 258 PHE 258 290 290 PHE PHE A . n 
A 1 259 LEU 259 291 291 LEU LEU A . n 
A 1 260 ASN 260 292 292 ASN ASN A . n 
A 1 261 LYS 261 293 293 LYS LYS A . n 
A 1 262 GLN 262 294 294 GLN GLN A . n 
A 1 263 ASP 263 295 295 ASP ASP A . n 
A 1 264 LEU 264 296 296 LEU LEU A . n 
A 1 265 LEU 265 297 297 LEU LEU A . n 
A 1 266 ALA 266 298 298 ALA ALA A . n 
A 1 267 GLU 267 299 299 GLU GLU A . n 
A 1 268 LYS 268 300 300 LYS LYS A . n 
A 1 269 VAL 269 301 301 VAL VAL A . n 
A 1 270 LEU 270 302 302 LEU LEU A . n 
A 1 271 ALA 271 303 303 ALA ALA A . n 
A 1 272 GLY 272 304 304 GLY GLY A . n 
A 1 273 LYS 273 305 305 LYS LYS A . n 
A 1 274 SER 274 306 306 SER SER A . n 
A 1 275 LYS 275 307 307 LYS LYS A . n 
A 1 276 ILE 276 308 308 ILE ILE A . n 
A 1 277 GLU 277 309 309 GLU GLU A . n 
A 1 278 ASP 278 310 310 ASP ASP A . n 
A 1 279 TYR 279 311 311 TYR TYR A . n 
A 1 280 PHE 280 312 312 PHE PHE A . n 
A 1 281 PRO 281 313 313 PRO PRO A . n 
A 1 282 GLU 282 314 314 GLU GLU A . n 
A 1 283 PHE 283 315 315 PHE PHE A . n 
A 1 284 ALA 284 316 316 ALA ALA A . n 
A 1 285 ARG 285 317 317 ARG ARG A . n 
A 1 286 TYR 286 318 318 TYR TYR A . n 
A 1 287 THR 287 319 319 THR THR A . n 
A 1 288 THR 288 320 320 THR THR A . n 
A 1 289 PRO 289 321 321 PRO PRO A . n 
A 1 290 GLU 290 322 322 GLU GLU A . n 
A 1 291 ASP 291 323 323 ASP ASP A . n 
A 1 292 ALA 292 324 324 ALA ALA A . n 
A 1 293 THR 293 325 325 THR THR A . n 
A 1 294 PRO 294 326 326 PRO PRO A . n 
A 1 295 GLU 295 327 327 GLU GLU A . n 
A 1 296 PRO 296 328 328 PRO PRO A . n 
A 1 297 GLY 297 329 329 GLY GLY A . n 
A 1 298 GLU 298 330 330 GLU GLU A . n 
A 1 299 ASP 299 331 331 ASP ASP A . n 
A 1 300 PRO 300 332 332 PRO PRO A . n 
A 1 301 ARG 301 333 333 ARG ARG A . n 
A 1 302 VAL 302 334 334 VAL VAL A . n 
A 1 303 THR 303 335 335 THR THR A . n 
A 1 304 ARG 304 336 336 ARG ARG A . n 
A 1 305 ALA 305 337 337 ALA ALA A . n 
A 1 306 LYS 306 338 338 LYS LYS A . n 
A 1 307 TYR 307 339 339 TYR TYR A . n 
A 1 308 PHE 308 340 340 PHE PHE A . n 
A 1 309 ILE 309 341 341 ILE ILE A . n 
A 1 310 ARG 310 342 342 ARG ARG A . n 
A 1 311 ASP 311 343 343 ASP ASP A . n 
A 1 312 GLU 312 344 344 GLU GLU A . n 
A 1 313 PHE 313 345 345 PHE PHE A . n 
A 1 314 LEU 314 346 346 LEU LEU A . n 
A 1 315 ARG 315 347 347 ARG ARG A . n 
A 1 316 ILE 316 348 348 ILE ILE A . n 
A 1 317 SER 317 349 349 SER SER A . n 
A 1 318 THR 318 350 350 THR THR A . n 
A 1 319 ALA 319 351 351 ALA ALA A . n 
A 1 320 SER 320 352 352 SER SER A . n 
A 1 321 GLY 321 353 353 GLY GLY A . n 
A 1 322 ASP 322 354 354 ASP ASP A . n 
A 1 323 GLY 323 355 355 GLY GLY A . n 
A 1 324 ARG 324 356 356 ARG ARG A . n 
A 1 325 HIS 325 357 357 HIS HIS A . n 
A 1 326 TYR 326 358 358 TYR TYR A . n 
A 1 327 CYS 327 359 359 CYS CYS A . n 
A 1 328 TYR 328 360 360 TYR TYR A . n 
A 1 329 PRO 329 361 361 PRO PRO A . n 
A 1 330 HIS 330 362 362 HIS HIS A . n 
A 1 331 PHE 331 363 363 PHE PHE A . n 
A 1 332 THR 332 364 364 THR THR A . n 
A 1 333 CYS 333 365 365 CYS CYS A . n 
A 1 334 SER 334 366 366 SER SER A . n 
A 1 335 VAL 335 367 367 VAL VAL A . n 
A 1 336 ASP 336 368 368 ASP ASP A . n 
A 1 337 THR 337 369 369 THR THR A . n 
A 1 338 GLU 338 370 370 GLU GLU A . n 
A 1 339 ASN 339 371 371 ASN ASN A . n 
A 1 340 ALA 340 372 372 ALA ALA A . n 
A 1 341 ARG 341 373 373 ARG ARG A . n 
A 1 342 ARG 342 374 374 ARG ARG A . n 
A 1 343 ILE 343 375 375 ILE ILE A . n 
A 1 344 PHE 344 376 376 PHE PHE A . n 
A 1 345 ASN 345 377 377 ASN ASN A . n 
A 1 346 ASP 346 378 378 ASP ASP A . n 
A 1 347 CYS 347 379 379 CYS CYS A . n 
A 1 348 ARG 348 380 380 ARG ARG A . n 
A 1 349 ASP 349 381 381 ASP ASP A . n 
A 1 350 ILE 350 382 382 ILE ILE A . n 
A 1 351 ILE 351 383 383 ILE ILE A . n 
A 1 352 GLN 352 384 384 GLN GLN A . n 
A 1 353 ARG 353 385 385 ARG ARG A . n 
A 1 354 MET 354 386 386 MET MET A . n 
A 1 355 HIS 355 387 387 HIS HIS A . n 
A 1 356 LEU 356 388 388 LEU LEU A . n 
A 1 357 ARG 357 389 389 ARG ARG A . n 
A 1 358 GLN 358 390 390 GLN GLN A . n 
A 1 359 TYR 359 391 391 TYR TYR A . n 
A 1 360 GLU 360 392 392 GLU GLU A . n 
A 1 361 LEU 361 393 393 LEU LEU A . n 
A 1 362 LEU 362 394 394 LEU LEU A . n 
B 2 1   MET 1   -4  ?   ?   ?   B . n 
B 2 2   GLY 2   -3  ?   ?   ?   B . n 
B 2 3   SER 3   -2  ?   ?   ?   B . n 
B 2 4   LEU 4   -1  ?   ?   ?   B . n 
B 2 5   LEU 5   0   ?   ?   ?   B . n 
B 2 6   GLN 6   1   ?   ?   ?   B . n 
B 2 7   SER 7   2   ?   ?   ?   B . n 
B 2 8   GLU 8   3   3   GLU GLU B . n 
B 2 9   LEU 9   4   4   LEU LEU B . n 
B 2 10  ASP 10  5   5   ASP ASP B . n 
B 2 11  GLN 11  6   6   GLN GLN B . n 
B 2 12  LEU 12  7   7   LEU LEU B . n 
B 2 13  ARG 13  8   8   ARG ARG B . n 
B 2 14  GLN 14  9   9   GLN GLN B . n 
B 2 15  GLU 15  10  10  GLU GLU B . n 
B 2 16  ALA 16  11  11  ALA ALA B . n 
B 2 17  GLU 17  12  12  GLU GLU B . n 
B 2 18  GLN 18  13  13  GLN GLN B . n 
B 2 19  LEU 19  14  14  LEU LEU B . n 
B 2 20  LYS 20  15  15  LYS LYS B . n 
B 2 21  ASN 21  16  16  ASN ASN B . n 
B 2 22  GLN 22  17  17  GLN GLN B . n 
B 2 23  ILE 23  18  18  ILE ILE B . n 
B 2 24  ARG 24  19  19  ARG ARG B . n 
B 2 25  ASP 25  20  20  ASP ASP B . n 
B 2 26  ALA 26  21  21  ALA ALA B . n 
B 2 27  ARG 27  22  22  ARG ARG B . n 
B 2 28  LYS 28  23  23  LYS LYS B . n 
B 2 29  ALA 29  24  24  ALA ALA B . n 
B 2 30  CYS 30  25  25  CYS CYS B . n 
B 2 31  ALA 31  26  26  ALA ALA B . n 
B 2 32  ASP 32  27  27  ASP ASP B . n 
B 2 33  ALA 33  28  28  ALA ALA B . n 
B 2 34  THR 34  29  29  THR THR B . n 
B 2 35  LEU 35  30  30  LEU LEU B . n 
B 2 36  SER 36  31  31  SER SER B . n 
B 2 37  GLN 37  32  32  GLN GLN B . n 
B 2 38  ILE 38  33  33  ILE ILE B . n 
B 2 39  THR 39  34  34  THR THR B . n 
B 2 40  ASN 40  35  35  ASN ASN B . n 
B 2 41  ASN 41  36  36  ASN ASN B . n 
B 2 42  ILE 42  37  37  ILE ILE B . n 
B 2 43  ASP 43  38  38  ASP ASP B . n 
B 2 44  PRO 44  39  39  PRO PRO B . n 
B 2 45  VAL 45  40  40  VAL VAL B . n 
B 2 46  GLY 46  41  41  GLY GLY B . n 
B 2 47  ARG 47  42  42  ARG ARG B . n 
B 2 48  ILE 48  43  43  ILE ILE B . n 
B 2 49  GLN 49  44  44  GLN GLN B . n 
B 2 50  MET 50  45  45  MET MET B . n 
B 2 51  ARG 51  46  46  ARG ARG B . n 
B 2 52  THR 52  47  47  THR THR B . n 
B 2 53  ARG 53  48  48  ARG ARG B . n 
B 2 54  ARG 54  49  49  ARG ARG B . n 
B 2 55  THR 55  50  50  THR THR B . n 
B 2 56  LEU 56  51  51  LEU LEU B . n 
B 2 57  ARG 57  52  52  ARG ARG B . n 
B 2 58  GLY 58  53  53  GLY GLY B . n 
B 2 59  HIS 59  54  54  HIS HIS B . n 
B 2 60  LEU 60  55  55  LEU LEU B . n 
B 2 61  ALA 61  56  56  ALA ALA B . n 
B 2 62  LYS 62  57  57  LYS LYS B . n 
B 2 63  ILE 63  58  58  ILE ILE B . n 
B 2 64  TYR 64  59  59  TYR TYR B . n 
B 2 65  ALA 65  60  60  ALA ALA B . n 
B 2 66  MET 66  61  61  MET MET B . n 
B 2 67  HIS 67  62  62  HIS HIS B . n 
B 2 68  TRP 68  63  63  TRP TRP B . n 
B 2 69  GLY 69  64  64  GLY GLY B . n 
B 2 70  THR 70  65  65  THR THR B . n 
B 2 71  ASP 71  66  66  ASP ASP B . n 
B 2 72  SER 72  67  67  SER SER B . n 
B 2 73  ARG 73  68  68  ARG ARG B . n 
B 2 74  LEU 74  69  69  LEU LEU B . n 
B 2 75  LEU 75  70  70  LEU LEU B . n 
B 2 76  VAL 76  71  71  VAL VAL B . n 
B 2 77  SER 77  72  72  SER SER B . n 
B 2 78  ALA 78  73  73  ALA ALA B . n 
B 2 79  SER 79  74  74  SER SER B . n 
B 2 80  GLN 80  75  75  GLN GLN B . n 
B 2 81  ASP 81  76  76  ASP ASP B . n 
B 2 82  GLY 82  77  77  GLY GLY B . n 
B 2 83  LYS 83  78  78  LYS LYS B . n 
B 2 84  LEU 84  79  79  LEU LEU B . n 
B 2 85  ILE 85  80  80  ILE ILE B . n 
B 2 86  ILE 86  81  81  ILE ILE B . n 
B 2 87  TRP 87  82  82  TRP TRP B . n 
B 2 88  ASP 88  83  83  ASP ASP B . n 
B 2 89  SER 89  84  84  SER SER B . n 
B 2 90  TYR 90  85  85  TYR TYR B . n 
B 2 91  THR 91  86  86  THR THR B . n 
B 2 92  THR 92  87  87  THR THR B . n 
B 2 93  ASN 93  88  88  ASN ASN B . n 
B 2 94  LYS 94  89  89  LYS LYS B . n 
B 2 95  VAL 95  90  90  VAL VAL B . n 
B 2 96  HIS 96  91  91  HIS HIS B . n 
B 2 97  ALA 97  92  92  ALA ALA B . n 
B 2 98  ILE 98  93  93  ILE ILE B . n 
B 2 99  PRO 99  94  94  PRO PRO B . n 
B 2 100 LEU 100 95  95  LEU LEU B . n 
B 2 101 ARG 101 96  96  ARG ARG B . n 
B 2 102 SER 102 97  97  SER SER B . n 
B 2 103 SER 103 98  98  SER SER B . n 
B 2 104 TRP 104 99  99  TRP TRP B . n 
B 2 105 VAL 105 100 100 VAL VAL B . n 
B 2 106 MET 106 101 101 MET MET B . n 
B 2 107 THR 107 102 102 THR THR B . n 
B 2 108 CYS 108 103 103 CYS CYS B . n 
B 2 109 ALA 109 104 104 ALA ALA B . n 
B 2 110 TYR 110 105 105 TYR TYR B . n 
B 2 111 ALA 111 106 106 ALA ALA B . n 
B 2 112 PRO 112 107 107 PRO PRO B . n 
B 2 113 SER 113 108 108 SER SER B . n 
B 2 114 GLY 114 109 109 GLY GLY B . n 
B 2 115 ASN 115 110 110 ASN ASN B . n 
B 2 116 TYR 116 111 111 TYR TYR B . n 
B 2 117 VAL 117 112 112 VAL VAL B . n 
B 2 118 ALA 118 113 113 ALA ALA B . n 
B 2 119 CYS 119 114 114 CYS CYS B . n 
B 2 120 GLY 120 115 115 GLY GLY B . n 
B 2 121 GLY 121 116 116 GLY GLY B . n 
B 2 122 LEU 122 117 117 LEU LEU B . n 
B 2 123 ASP 123 118 118 ASP ASP B . n 
B 2 124 ASN 124 119 119 ASN ASN B . n 
B 2 125 ILE 125 120 120 ILE ILE B . n 
B 2 126 CYS 126 121 121 CYS CYS B . n 
B 2 127 SER 127 122 122 SER SER B . n 
B 2 128 ILE 128 123 123 ILE ILE B . n 
B 2 129 TYR 129 124 124 TYR TYR B . n 
B 2 130 ASN 130 125 125 ASN ASN B . n 
B 2 131 LEU 131 126 126 LEU LEU B . n 
B 2 132 LYS 132 127 127 LYS LYS B . n 
B 2 133 THR 133 128 128 THR THR B . n 
B 2 134 ARG 134 129 129 ARG ARG B . n 
B 2 135 GLU 135 130 130 GLU GLU B . n 
B 2 136 GLY 136 131 131 GLY GLY B . n 
B 2 137 ASN 137 132 132 ASN ASN B . n 
B 2 138 VAL 138 133 133 VAL VAL B . n 
B 2 139 ARG 139 134 134 ARG ARG B . n 
B 2 140 VAL 140 135 135 VAL VAL B . n 
B 2 141 SER 141 136 136 SER SER B . n 
B 2 142 ARG 142 137 137 ARG ARG B . n 
B 2 143 GLU 143 138 138 GLU GLU B . n 
B 2 144 LEU 144 139 139 LEU LEU B . n 
B 2 145 ALA 145 140 140 ALA ALA B . n 
B 2 146 GLY 146 141 141 GLY GLY B . n 
B 2 147 HIS 147 142 142 HIS HIS B . n 
B 2 148 THR 148 143 143 THR THR B . n 
B 2 149 GLY 149 144 144 GLY GLY B . n 
B 2 150 TYR 150 145 145 TYR TYR B . n 
B 2 151 LEU 151 146 146 LEU LEU B . n 
B 2 152 SER 152 147 147 SER SER B . n 
B 2 153 CYS 153 148 148 CYS CYS B . n 
B 2 154 CYS 154 149 149 CYS CYS B . n 
B 2 155 ARG 155 150 150 ARG ARG B . n 
B 2 156 PHE 156 151 151 PHE PHE B . n 
B 2 157 LEU 157 152 152 LEU LEU B . n 
B 2 158 ASP 158 153 153 ASP ASP B . n 
B 2 159 ASP 159 154 154 ASP ASP B . n 
B 2 160 ASN 160 155 155 ASN ASN B . n 
B 2 161 GLN 161 156 156 GLN GLN B . n 
B 2 162 ILE 162 157 157 ILE ILE B . n 
B 2 163 VAL 163 158 158 VAL VAL B . n 
B 2 164 THR 164 159 159 THR THR B . n 
B 2 165 SER 165 160 160 SER SER B . n 
B 2 166 SER 166 161 161 SER SER B . n 
B 2 167 GLY 167 162 162 GLY GLY B . n 
B 2 168 ASP 168 163 163 ASP ASP B . n 
B 2 169 THR 169 164 164 THR THR B . n 
B 2 170 THR 170 165 165 THR THR B . n 
B 2 171 CYS 171 166 166 CYS CYS B . n 
B 2 172 ALA 172 167 167 ALA ALA B . n 
B 2 173 LEU 173 168 168 LEU LEU B . n 
B 2 174 TRP 174 169 169 TRP TRP B . n 
B 2 175 ASP 175 170 170 ASP ASP B . n 
B 2 176 ILE 176 171 171 ILE ILE B . n 
B 2 177 GLU 177 172 172 GLU GLU B . n 
B 2 178 THR 178 173 173 THR THR B . n 
B 2 179 GLY 179 174 174 GLY GLY B . n 
B 2 180 GLN 180 175 175 GLN GLN B . n 
B 2 181 GLN 181 176 176 GLN GLN B . n 
B 2 182 THR 182 177 177 THR THR B . n 
B 2 183 THR 183 178 178 THR THR B . n 
B 2 184 THR 184 179 179 THR THR B . n 
B 2 185 PHE 185 180 180 PHE PHE B . n 
B 2 186 THR 186 181 181 THR THR B . n 
B 2 187 GLY 187 182 182 GLY GLY B . n 
B 2 188 HIS 188 183 183 HIS HIS B . n 
B 2 189 THR 189 184 184 THR THR B . n 
B 2 190 GLY 190 185 185 GLY GLY B . n 
B 2 191 ASP 191 186 186 ASP ASP B . n 
B 2 192 VAL 192 187 187 VAL VAL B . n 
B 2 193 MET 193 188 188 MET MET B . n 
B 2 194 SER 194 189 189 SER SER B . n 
B 2 195 LEU 195 190 190 LEU LEU B . n 
B 2 196 SER 196 191 191 SER SER B . n 
B 2 197 LEU 197 192 192 LEU LEU B . n 
B 2 198 ALA 198 193 193 ALA ALA B . n 
B 2 199 PRO 199 194 194 PRO PRO B . n 
B 2 200 ASP 200 195 195 ASP ASP B . n 
B 2 201 THR 201 196 196 THR THR B . n 
B 2 202 ARG 202 197 197 ARG ARG B . n 
B 2 203 LEU 203 198 198 LEU LEU B . n 
B 2 204 PHE 204 199 199 PHE PHE B . n 
B 2 205 VAL 205 200 200 VAL VAL B . n 
B 2 206 SER 206 201 201 SER SER B . n 
B 2 207 GLY 207 202 202 GLY GLY B . n 
B 2 208 ALA 208 203 203 ALA ALA B . n 
B 2 209 CYS 209 204 204 CYS CYS B . n 
B 2 210 ASP 210 205 205 ASP ASP B . n 
B 2 211 ALA 211 206 206 ALA ALA B . n 
B 2 212 SER 212 207 207 SER SER B . n 
B 2 213 ALA 213 208 208 ALA ALA B . n 
B 2 214 LYS 214 209 209 LYS LYS B . n 
B 2 215 LEU 215 210 210 LEU LEU B . n 
B 2 216 TRP 216 211 211 TRP TRP B . n 
B 2 217 ASP 217 212 212 ASP ASP B . n 
B 2 218 VAL 218 213 213 VAL VAL B . n 
B 2 219 ARG 219 214 214 ARG ARG B . n 
B 2 220 GLU 220 215 215 GLU GLU B . n 
B 2 221 GLY 221 216 216 GLY GLY B . n 
B 2 222 MET 222 217 217 MET MET B . n 
B 2 223 CYS 223 218 218 CYS CYS B . n 
B 2 224 ARG 224 219 219 ARG ARG B . n 
B 2 225 GLN 225 220 220 GLN GLN B . n 
B 2 226 THR 226 221 221 THR THR B . n 
B 2 227 PHE 227 222 222 PHE PHE B . n 
B 2 228 THR 228 223 223 THR THR B . n 
B 2 229 GLY 229 224 224 GLY GLY B . n 
B 2 230 HIS 230 225 225 HIS HIS B . n 
B 2 231 GLU 231 226 226 GLU GLU B . n 
B 2 232 SER 232 227 227 SER SER B . n 
B 2 233 ASP 233 228 228 ASP ASP B . n 
B 2 234 ILE 234 229 229 ILE ILE B . n 
B 2 235 ASN 235 230 230 ASN ASN B . n 
B 2 236 ALA 236 231 231 ALA ALA B . n 
B 2 237 ILE 237 232 232 ILE ILE B . n 
B 2 238 CYS 238 233 233 CYS CYS B . n 
B 2 239 PHE 239 234 234 PHE PHE B . n 
B 2 240 PHE 240 235 235 PHE PHE B . n 
B 2 241 PRO 241 236 236 PRO PRO B . n 
B 2 242 ASN 242 237 237 ASN ASN B . n 
B 2 243 GLY 243 238 238 GLY GLY B . n 
B 2 244 ASN 244 239 239 ASN ASN B . n 
B 2 245 ALA 245 240 240 ALA ALA B . n 
B 2 246 PHE 246 241 241 PHE PHE B . n 
B 2 247 ALA 247 242 242 ALA ALA B . n 
B 2 248 THR 248 243 243 THR THR B . n 
B 2 249 GLY 249 244 244 GLY GLY B . n 
B 2 250 SER 250 245 245 SER SER B . n 
B 2 251 ASP 251 246 246 ASP ASP B . n 
B 2 252 ASP 252 247 247 ASP ASP B . n 
B 2 253 ALA 253 248 248 ALA ALA B . n 
B 2 254 THR 254 249 249 THR THR B . n 
B 2 255 CYS 255 250 250 CYS CYS B . n 
B 2 256 ARG 256 251 251 ARG ARG B . n 
B 2 257 LEU 257 252 252 LEU LEU B . n 
B 2 258 PHE 258 253 253 PHE PHE B . n 
B 2 259 ASP 259 254 254 ASP ASP B . n 
B 2 260 LEU 260 255 255 LEU LEU B . n 
B 2 261 ARG 261 256 256 ARG ARG B . n 
B 2 262 ALA 262 257 257 ALA ALA B . n 
B 2 263 ASP 263 258 258 ASP ASP B . n 
B 2 264 GLN 264 259 259 GLN GLN B . n 
B 2 265 GLU 265 260 260 GLU GLU B . n 
B 2 266 LEU 266 261 261 LEU LEU B . n 
B 2 267 MET 267 262 262 MET MET B . n 
B 2 268 THR 268 263 263 THR THR B . n 
B 2 269 TYR 269 264 264 TYR TYR B . n 
B 2 270 SER 270 265 265 SER SER B . n 
B 2 271 HIS 271 266 266 HIS HIS B . n 
B 2 272 ASP 272 267 267 ASP ASP B . n 
B 2 273 ASN 273 268 268 ASN ASN B . n 
B 2 274 ILE 274 269 269 ILE ILE B . n 
B 2 275 ILE 275 270 270 ILE ILE B . n 
B 2 276 CYS 276 271 271 CYS CYS B . n 
B 2 277 GLY 277 272 272 GLY GLY B . n 
B 2 278 ILE 278 273 273 ILE ILE B . n 
B 2 279 THR 279 274 274 THR THR B . n 
B 2 280 SER 280 275 275 SER SER B . n 
B 2 281 VAL 281 276 276 VAL VAL B . n 
B 2 282 SER 282 277 277 SER SER B . n 
B 2 283 PHE 283 278 278 PHE PHE B . n 
B 2 284 SER 284 279 279 SER SER B . n 
B 2 285 LYS 285 280 280 LYS LYS B . n 
B 2 286 SER 286 281 281 SER SER B . n 
B 2 287 GLY 287 282 282 GLY GLY B . n 
B 2 288 ARG 288 283 283 ARG ARG B . n 
B 2 289 LEU 289 284 284 LEU LEU B . n 
B 2 290 LEU 290 285 285 LEU LEU B . n 
B 2 291 LEU 291 286 286 LEU LEU B . n 
B 2 292 ALA 292 287 287 ALA ALA B . n 
B 2 293 GLY 293 288 288 GLY GLY B . n 
B 2 294 TYR 294 289 289 TYR TYR B . n 
B 2 295 ASP 295 290 290 ASP ASP B . n 
B 2 296 ASP 296 291 291 ASP ASP B . n 
B 2 297 PHE 297 292 292 PHE PHE B . n 
B 2 298 ASN 298 293 293 ASN ASN B . n 
B 2 299 CYS 299 294 294 CYS CYS B . n 
B 2 300 ASN 300 295 295 ASN ASN B . n 
B 2 301 VAL 301 296 296 VAL VAL B . n 
B 2 302 TRP 302 297 297 TRP TRP B . n 
B 2 303 ASP 303 298 298 ASP ASP B . n 
B 2 304 ALA 304 299 299 ALA ALA B . n 
B 2 305 LEU 305 300 300 LEU LEU B . n 
B 2 306 LYS 306 301 301 LYS LYS B . n 
B 2 307 ALA 307 302 302 ALA ALA B . n 
B 2 308 ASP 308 303 303 ASP ASP B . n 
B 2 309 ARG 309 304 304 ARG ARG B . n 
B 2 310 ALA 310 305 305 ALA ALA B . n 
B 2 311 GLY 311 306 306 GLY GLY B . n 
B 2 312 VAL 312 307 307 VAL VAL B . n 
B 2 313 LEU 313 308 308 LEU LEU B . n 
B 2 314 ALA 314 309 309 ALA ALA B . n 
B 2 315 GLY 315 310 310 GLY GLY B . n 
B 2 316 HIS 316 311 311 HIS HIS B . n 
B 2 317 ASP 317 312 312 ASP ASP B . n 
B 2 318 ASN 318 313 313 ASN ASN B . n 
B 2 319 ARG 319 314 314 ARG ARG B . n 
B 2 320 VAL 320 315 315 VAL VAL B . n 
B 2 321 SER 321 316 316 SER SER B . n 
B 2 322 CYS 322 317 317 CYS CYS B . n 
B 2 323 LEU 323 318 318 LEU LEU B . n 
B 2 324 GLY 324 319 319 GLY GLY B . n 
B 2 325 VAL 325 320 320 VAL VAL B . n 
B 2 326 THR 326 321 321 THR THR B . n 
B 2 327 ASP 327 322 322 ASP ASP B . n 
B 2 328 ASP 328 323 323 ASP ASP B . n 
B 2 329 GLY 329 324 324 GLY GLY B . n 
B 2 330 MET 330 325 325 MET MET B . n 
B 2 331 ALA 331 326 326 ALA ALA B . n 
B 2 332 VAL 332 327 327 VAL VAL B . n 
B 2 333 ALA 333 328 328 ALA ALA B . n 
B 2 334 THR 334 329 329 THR THR B . n 
B 2 335 GLY 335 330 330 GLY GLY B . n 
B 2 336 SER 336 331 331 SER SER B . n 
B 2 337 TRP 337 332 332 TRP TRP B . n 
B 2 338 ASP 338 333 333 ASP ASP B . n 
B 2 339 SER 339 334 334 SER SER B . n 
B 2 340 PHE 340 335 335 PHE PHE B . n 
B 2 341 LEU 341 336 336 LEU LEU B . n 
B 2 342 LYS 342 337 337 LYS LYS B . n 
B 2 343 ILE 343 338 338 ILE ILE B . n 
B 2 344 TRP 344 339 339 TRP TRP B . n 
B 2 345 ASN 345 340 340 ASN ASN B . n 
C 3 1   MET 1   1   ?   ?   ?   G . n 
C 3 2   ALA 2   2   ?   ?   ?   G . n 
C 3 3   SER 3   3   ?   ?   ?   G . n 
C 3 4   ASN 4   4   ?   ?   ?   G . n 
C 3 5   ASN 5   5   ?   ?   ?   G . n 
C 3 6   THR 6   6   ?   ?   ?   G . n 
C 3 7   ALA 7   7   ?   ?   ?   G . n 
C 3 8   SER 8   8   ?   ?   ?   G . n 
C 3 9   ILE 9   9   ?   ?   ?   G . n 
C 3 10  ALA 10  10  ?   ?   ?   G . n 
C 3 11  GLN 11  11  11  GLN GLN G . n 
C 3 12  ALA 12  12  12  ALA ALA G . n 
C 3 13  ARG 13  13  13  ARG ARG G . n 
C 3 14  LYS 14  14  14  LYS LYS G . n 
C 3 15  LEU 15  15  15  LEU LEU G . n 
C 3 16  VAL 16  16  16  VAL VAL G . n 
C 3 17  GLU 17  17  17  GLU GLU G . n 
C 3 18  GLN 18  18  18  GLN GLN G . n 
C 3 19  LEU 19  19  19  LEU LEU G . n 
C 3 20  LYS 20  20  20  LYS LYS G . n 
C 3 21  MET 21  21  21  MET MET G . n 
C 3 22  GLU 22  22  22  GLU GLU G . n 
C 3 23  ALA 23  23  23  ALA ALA G . n 
C 3 24  ASN 24  24  24  ASN ASN G . n 
C 3 25  ILE 25  25  25  ILE ILE G . n 
C 3 26  ASP 26  26  26  ASP ASP G . n 
C 3 27  ARG 27  27  27  ARG ARG G . n 
C 3 28  ILE 28  28  28  ILE ILE G . n 
C 3 29  LYS 29  29  29  LYS LYS G . n 
C 3 30  VAL 30  30  30  VAL VAL G . n 
C 3 31  SER 31  31  31  SER SER G . n 
C 3 32  LYS 32  32  32  LYS LYS G . n 
C 3 33  ALA 33  33  33  ALA ALA G . n 
C 3 34  ALA 34  34  34  ALA ALA G . n 
C 3 35  ALA 35  35  35  ALA ALA G . n 
C 3 36  ASP 36  36  36  ASP ASP G . n 
C 3 37  LEU 37  37  37  LEU LEU G . n 
C 3 38  MET 38  38  38  MET MET G . n 
C 3 39  ALA 39  39  39  ALA ALA G . n 
C 3 40  TYR 40  40  40  TYR TYR G . n 
C 3 41  CYS 41  41  41  CYS CYS G . n 
C 3 42  GLU 42  42  42  GLU GLU G . n 
C 3 43  ALA 43  43  43  ALA ALA G . n 
C 3 44  HIS 44  44  44  HIS HIS G . n 
C 3 45  ALA 45  45  45  ALA ALA G . n 
C 3 46  LYS 46  46  46  LYS LYS G . n 
C 3 47  GLU 47  47  47  GLU GLU G . n 
C 3 48  ASP 48  48  48  ASP ASP G . n 
C 3 49  PRO 49  49  49  PRO PRO G . n 
C 3 50  LEU 50  50  50  LEU LEU G . n 
C 3 51  LEU 51  51  51  LEU LEU G . n 
C 3 52  THR 52  52  52  THR THR G . n 
C 3 53  PRO 53  53  53  PRO PRO G . n 
C 3 54  VAL 54  54  54  VAL VAL G . n 
C 3 55  PRO 55  55  55  PRO PRO G . n 
C 3 56  ALA 56  56  56  ALA ALA G . n 
C 3 57  SER 57  57  57  SER SER G . n 
C 3 58  GLU 58  58  58  GLU GLU G . n 
C 3 59  ASN 59  59  59  ASN ASN G . n 
C 3 60  PRO 60  60  60  PRO PRO G . n 
C 3 61  PHE 61  61  61  PHE PHE G . n 
C 3 62  ARG 62  62  ?   ?   ?   G . n 
C 3 63  GLU 63  63  ?   ?   ?   G . n 
C 3 64  LYS 64  64  ?   ?   ?   G . n 
C 3 65  LYS 65  65  ?   ?   ?   G . n 
C 3 66  PHE 66  66  ?   ?   ?   G . n 
C 3 67  PHE 67  67  ?   ?   ?   G . n 
C 3 68  CYS 68  68  ?   ?   ?   G . n 
C 3 69  ALA 69  69  ?   ?   ?   G . n 
C 3 70  ILE 70  70  ?   ?   ?   G . n 
C 3 71  LEU 71  71  ?   ?   ?   G . n 
D 4 1   MET 1   1   ?   ?   ?   R . n 
D 4 2   GLY 2   2   ?   ?   ?   R . n 
D 4 3   ASN 3   3   ?   ?   ?   R . n 
D 4 4   ILE 4   4   ?   ?   ?   R . n 
D 4 5   THR 5   5   ?   ?   ?   R . n 
D 4 6   ALA 6   6   ?   ?   ?   R . n 
D 4 7   ASP 7   7   ?   ?   ?   R . n 
D 4 8   ASN 8   8   ?   ?   ?   R . n 
D 4 9   SER 9   9   ?   ?   ?   R . n 
D 4 10  SER 10  10  ?   ?   ?   R . n 
D 4 11  MET 11  11  ?   ?   ?   R . n 
D 4 12  SER 12  12  12  SER SER R . n 
D 4 13  CYS 13  13  13  CYS CYS R . n 
D 4 14  THR 14  14  14  THR THR R . n 
D 4 15  ILE 15  15  15  ILE ILE R . n 
D 4 16  ASP 16  16  16  ASP ASP R . n 
D 4 17  HIS 17  17  17  HIS HIS R . n 
D 4 18  THR 18  18  18  THR THR R . n 
D 4 19  ILE 19  19  19  ILE ILE R . n 
D 4 20  HIS 20  20  20  HIS HIS R . n 
D 4 21  GLN 21  21  21  GLN GLN R . n 
D 4 22  THR 22  22  22  THR THR R . n 
D 4 23  LEU 23  23  23  LEU LEU R . n 
D 4 24  ALA 24  24  24  ALA ALA R . n 
D 4 25  PRO 25  25  25  PRO PRO R . n 
D 4 26  VAL 26  26  26  VAL VAL R . n 
D 4 27  VAL 27  27  27  VAL VAL R . n 
D 4 28  TYR 28  28  28  TYR TYR R . n 
D 4 29  VAL 29  29  29  VAL VAL R . n 
D 4 30  THR 30  30  30  THR THR R . n 
D 4 31  VAL 31  31  31  VAL VAL R . n 
D 4 32  LEU 32  32  32  LEU LEU R . n 
D 4 33  VAL 33  33  33  VAL VAL R . n 
D 4 34  VAL 34  34  34  VAL VAL R . n 
D 4 35  GLY 35  35  35  GLY GLY R . n 
D 4 36  PHE 36  36  36  PHE PHE R . n 
D 4 37  PRO 37  37  37  PRO PRO R . n 
D 4 38  ALA 38  38  38  ALA ALA R . n 
D 4 39  ASN 39  39  39  ASN ASN R . n 
D 4 40  CYS 40  40  40  CYS CYS R . n 
D 4 41  LEU 41  41  41  LEU LEU R . n 
D 4 42  SER 42  42  42  SER SER R . n 
D 4 43  LEU 43  43  43  LEU LEU R . n 
D 4 44  TYR 44  44  44  TYR TYR R . n 
D 4 45  PHE 45  45  45  PHE PHE R . n 
D 4 46  GLY 46  46  46  GLY GLY R . n 
D 4 47  TYR 47  47  47  TYR TYR R . n 
D 4 48  LEU 48  48  48  LEU LEU R . n 
D 4 49  GLN 49  49  49  GLN GLN R . n 
D 4 50  ILE 50  50  50  ILE ILE R . n 
D 4 51  LYS 51  51  51  LYS LYS R . n 
D 4 52  ALA 52  52  52  ALA ALA R . n 
D 4 53  ARG 53  53  53  ARG ARG R . n 
D 4 54  ASN 54  54  54  ASN ASN R . n 
D 4 55  GLU 55  55  55  GLU GLU R . n 
D 4 56  LEU 56  56  56  LEU LEU R . n 
D 4 57  GLY 57  57  57  GLY GLY R . n 
D 4 58  VAL 58  58  58  VAL VAL R . n 
D 4 59  TYR 59  59  59  TYR TYR R . n 
D 4 60  LEU 60  60  60  LEU LEU R . n 
D 4 61  CYS 61  61  61  CYS CYS R . n 
D 4 62  ASN 62  62  62  ASN ASN R . n 
D 4 63  LEU 63  63  63  LEU LEU R . n 
D 4 64  THR 64  64  64  THR THR R . n 
D 4 65  VAL 65  65  65  VAL VAL R . n 
D 4 66  ALA 66  66  66  ALA ALA R . n 
D 4 67  ASP 67  67  67  ASP ASP R . n 
D 4 68  LEU 68  68  68  LEU LEU R . n 
D 4 69  PHE 69  69  69  PHE PHE R . n 
D 4 70  TYR 70  70  70  TYR TYR R . n 
D 4 71  ILE 71  71  71  ILE ILE R . n 
D 4 72  CYS 72  72  72  CYS CYS R . n 
D 4 73  SER 73  73  73  SER SER R . n 
D 4 74  LEU 74  74  74  LEU LEU R . n 
D 4 75  PRO 75  75  75  PRO PRO R . n 
D 4 76  PHE 76  76  76  PHE PHE R . n 
D 4 77  TRP 77  77  77  TRP TRP R . n 
D 4 78  LEU 78  78  78  LEU LEU R . n 
D 4 79  GLN 79  79  79  GLN GLN R . n 
D 4 80  TYR 80  80  80  TYR TYR R . n 
D 4 81  VAL 81  81  81  VAL VAL R . n 
D 4 82  LEU 82  82  82  LEU LEU R . n 
D 4 83  GLN 83  83  83  GLN GLN R . n 
D 4 84  HIS 84  84  84  HIS HIS R . n 
D 4 85  ASP 85  85  85  ASP ASP R . n 
D 4 86  ASN 86  86  86  ASN ASN R . n 
D 4 87  TRP 87  87  87  TRP TRP R . n 
D 4 88  SER 88  88  88  SER SER R . n 
D 4 89  HIS 89  89  89  HIS HIS R . n 
D 4 90  GLY 90  90  90  GLY GLY R . n 
D 4 91  ASP 91  91  91  ASP ASP R . n 
D 4 92  LEU 92  92  92  LEU LEU R . n 
D 4 93  SER 93  93  93  SER SER R . n 
D 4 94  CYS 94  94  94  CYS CYS R . n 
D 4 95  GLN 95  95  95  GLN GLN R . n 
D 4 96  VAL 96  96  96  VAL VAL R . n 
D 4 97  CYS 97  97  97  CYS CYS R . n 
D 4 98  GLY 98  98  98  GLY GLY R . n 
D 4 99  ILE 99  99  99  ILE ILE R . n 
D 4 100 LEU 100 100 100 LEU LEU R . n 
D 4 101 LEU 101 101 101 LEU LEU R . n 
D 4 102 TYR 102 102 102 TYR TYR R . n 
D 4 103 GLU 103 103 103 GLU GLU R . n 
D 4 104 ASN 104 104 104 ASN ASN R . n 
D 4 105 ILE 105 105 105 ILE ILE R . n 
D 4 106 TYR 106 106 106 TYR TYR R . n 
D 4 107 ILE 107 107 107 ILE ILE R . n 
D 4 108 SER 108 108 108 SER SER R . n 
D 4 109 VAL 109 109 109 VAL VAL R . n 
D 4 110 GLY 110 110 110 GLY GLY R . n 
D 4 111 PHE 111 111 111 PHE PHE R . n 
D 4 112 LEU 112 112 112 LEU LEU R . n 
D 4 113 CYS 113 113 113 CYS CYS R . n 
D 4 114 CYS 114 114 114 CYS CYS R . n 
D 4 115 ILE 115 115 115 ILE ILE R . n 
D 4 116 SER 116 116 116 SER SER R . n 
D 4 117 VAL 117 117 117 VAL VAL R . n 
D 4 118 ASP 118 118 118 ASP ASP R . n 
D 4 119 ARG 119 119 119 ARG ARG R . n 
D 4 120 TYR 120 120 120 TYR TYR R . n 
D 4 121 LEU 121 121 121 LEU LEU R . n 
D 4 122 ALA 122 122 122 ALA ALA R . n 
D 4 123 VAL 123 123 123 VAL VAL R . n 
D 4 124 ALA 124 124 124 ALA ALA R . n 
D 4 125 HIS 125 125 125 HIS HIS R . n 
D 4 126 PRO 126 126 126 PRO PRO R . n 
D 4 127 PHE 127 127 127 PHE PHE R . n 
D 4 128 ARG 128 128 128 ARG ARG R . n 
D 4 129 PHE 129 129 129 PHE PHE R . n 
D 4 130 HIS 130 130 130 HIS HIS R . n 
D 4 131 GLN 131 131 131 GLN GLN R . n 
D 4 132 PHE 132 132 132 PHE PHE R . n 
D 4 133 ARG 133 133 133 ARG ARG R . n 
D 4 134 THR 134 134 134 THR THR R . n 
D 4 135 LEU 135 135 135 LEU LEU R . n 
D 4 136 LYS 136 136 136 LYS LYS R . n 
D 4 137 ALA 137 137 137 ALA ALA R . n 
D 4 138 ALA 138 138 138 ALA ALA R . n 
D 4 139 VAL 139 139 139 VAL VAL R . n 
D 4 140 GLY 140 140 140 GLY GLY R . n 
D 4 141 VAL 141 141 141 VAL VAL R . n 
D 4 142 SER 142 142 142 SER SER R . n 
D 4 143 VAL 143 143 143 VAL VAL R . n 
D 4 144 VAL 144 144 144 VAL VAL R . n 
D 4 145 ILE 145 145 145 ILE ILE R . n 
D 4 146 TRP 146 146 146 TRP TRP R . n 
D 4 147 ALA 147 147 147 ALA ALA R . n 
D 4 148 LYS 148 148 148 LYS LYS R . n 
D 4 149 GLU 149 149 149 GLU GLU R . n 
D 4 150 LEU 150 150 150 LEU LEU R . n 
D 4 151 LEU 151 151 151 LEU LEU R . n 
D 4 152 THR 152 152 152 THR THR R . n 
D 4 153 SER 153 153 153 SER SER R . n 
D 4 154 ILE 154 154 154 ILE ILE R . n 
D 4 155 TYR 155 155 155 TYR TYR R . n 
D 4 156 PHE 156 156 156 PHE PHE R . n 
D 4 157 LEU 157 157 157 LEU LEU R . n 
D 4 158 MET 158 158 158 MET MET R . n 
D 4 159 HIS 159 159 159 HIS HIS R . n 
D 4 160 GLU 160 160 160 GLU GLU R . n 
D 4 161 GLU 161 161 161 GLU GLU R . n 
D 4 162 VAL 162 162 162 VAL VAL R . n 
D 4 163 ILE 163 163 163 ILE ILE R . n 
D 4 164 GLU 164 164 164 GLU GLU R . n 
D 4 165 ASP 165 165 165 ASP ASP R . n 
D 4 166 GLU 166 166 166 GLU GLU R . n 
D 4 167 ASN 167 167 167 ASN ASN R . n 
D 4 168 GLN 168 168 168 GLN GLN R . n 
D 4 169 HIS 169 169 169 HIS HIS R . n 
D 4 170 ARG 170 170 170 ARG ARG R . n 
D 4 171 VAL 171 171 171 VAL VAL R . n 
D 4 172 CYS 172 172 172 CYS CYS R . n 
D 4 173 PHE 173 173 173 PHE PHE R . n 
D 4 174 GLU 174 174 174 GLU GLU R . n 
D 4 175 HIS 175 175 175 HIS HIS R . n 
D 4 176 TYR 176 176 176 TYR TYR R . n 
D 4 177 PRO 177 177 177 PRO PRO R . n 
D 4 178 ILE 178 178 178 ILE ILE R . n 
D 4 179 GLN 179 179 179 GLN GLN R . n 
D 4 180 ALA 180 180 180 ALA ALA R . n 
D 4 181 TRP 181 181 181 TRP TRP R . n 
D 4 182 GLN 182 182 182 GLN GLN R . n 
D 4 183 ARG 183 183 183 ARG ARG R . n 
D 4 184 ALA 184 184 184 ALA ALA R . n 
D 4 185 ILE 185 185 185 ILE ILE R . n 
D 4 186 ASN 186 186 186 ASN ASN R . n 
D 4 187 TYR 187 187 187 TYR TYR R . n 
D 4 188 TYR 188 188 188 TYR TYR R . n 
D 4 189 ARG 189 189 189 ARG ARG R . n 
D 4 190 PHE 190 190 190 PHE PHE R . n 
D 4 191 LEU 191 191 191 LEU LEU R . n 
D 4 192 VAL 192 192 192 VAL VAL R . n 
D 4 193 GLY 193 193 193 GLY GLY R . n 
D 4 194 PHE 194 194 194 PHE PHE R . n 
D 4 195 LEU 195 195 195 LEU LEU R . n 
D 4 196 PHE 196 196 196 PHE PHE R . n 
D 4 197 PRO 197 197 197 PRO PRO R . n 
D 4 198 ILE 198 198 198 ILE ILE R . n 
D 4 199 CYS 199 199 199 CYS CYS R . n 
D 4 200 LEU 200 200 200 LEU LEU R . n 
D 4 201 LEU 201 201 201 LEU LEU R . n 
D 4 202 LEU 202 202 202 LEU LEU R . n 
D 4 203 ALA 203 203 203 ALA ALA R . n 
D 4 204 SER 204 204 204 SER SER R . n 
D 4 205 TYR 205 205 205 TYR TYR R . n 
D 4 206 GLN 206 206 206 GLN GLN R . n 
D 4 207 GLY 207 207 207 GLY GLY R . n 
D 4 208 ILE 208 208 208 ILE ILE R . n 
D 4 209 LEU 209 209 209 LEU LEU R . n 
D 4 210 ARG 210 210 210 ARG ARG R . n 
D 4 211 ALA 211 211 211 ALA ALA R . n 
D 4 212 VAL 212 212 212 VAL VAL R . n 
D 4 213 ARG 213 213 213 ARG ARG R . n 
D 4 214 ARG 214 214 214 ARG ARG R . n 
D 4 215 SER 215 215 215 SER SER R . n 
D 4 216 HIS 216 216 216 HIS HIS R . n 
D 4 217 GLY 217 217 217 GLY GLY R . n 
D 4 218 THR 218 218 218 THR THR R . n 
D 4 219 GLN 219 219 219 GLN GLN R . n 
D 4 220 LYS 220 220 220 LYS LYS R . n 
D 4 221 SER 221 221 221 SER SER R . n 
D 4 222 ARG 222 222 222 ARG ARG R . n 
D 4 223 LYS 223 223 223 LYS LYS R . n 
D 4 224 ASP 224 224 224 ASP ASP R . n 
D 4 225 GLN 225 225 225 GLN GLN R . n 
D 4 226 ILE 226 226 226 ILE ILE R . n 
D 4 227 GLN 227 227 227 GLN GLN R . n 
D 4 228 ARG 228 228 228 ARG ARG R . n 
D 4 229 LEU 229 229 229 LEU LEU R . n 
D 4 230 VAL 230 230 230 VAL VAL R . n 
D 4 231 LEU 231 231 231 LEU LEU R . n 
D 4 232 SER 232 232 232 SER SER R . n 
D 4 233 THR 233 233 233 THR THR R . n 
D 4 234 VAL 234 234 234 VAL VAL R . n 
D 4 235 VAL 235 235 235 VAL VAL R . n 
D 4 236 ILE 236 236 236 ILE ILE R . n 
D 4 237 PHE 237 237 237 PHE PHE R . n 
D 4 238 LEU 238 238 238 LEU LEU R . n 
D 4 239 ALA 239 239 239 ALA ALA R . n 
D 4 240 CYS 240 240 240 CYS CYS R . n 
D 4 241 PHE 241 241 241 PHE PHE R . n 
D 4 242 LEU 242 242 242 LEU LEU R . n 
D 4 243 PRO 243 243 243 PRO PRO R . n 
D 4 244 TYR 244 244 244 TYR TYR R . n 
D 4 245 HIS 245 245 245 HIS HIS R . n 
D 4 246 VAL 246 246 246 VAL VAL R . n 
D 4 247 LEU 247 247 247 LEU LEU R . n 
D 4 248 LEU 248 248 248 LEU LEU R . n 
D 4 249 LEU 249 249 249 LEU LEU R . n 
D 4 250 VAL 250 250 250 VAL VAL R . n 
D 4 251 ARG 251 251 251 ARG ARG R . n 
D 4 252 SER 252 252 252 SER SER R . n 
D 4 253 VAL 253 253 253 VAL VAL R . n 
D 4 254 TRP 254 254 254 TRP TRP R . n 
D 4 255 GLU 255 255 255 GLU GLU R . n 
D 4 256 ALA 256 256 256 ALA ALA R . n 
D 4 257 SER 257 257 257 SER SER R . n 
D 4 258 CYS 258 258 258 CYS CYS R . n 
D 4 259 ASP 259 259 259 ASP ASP R . n 
D 4 260 PHE 260 260 260 PHE PHE R . n 
D 4 261 ALA 261 261 261 ALA ALA R . n 
D 4 262 LYS 262 262 262 LYS LYS R . n 
D 4 263 GLY 263 263 263 GLY GLY R . n 
D 4 264 VAL 264 264 264 VAL VAL R . n 
D 4 265 PHE 265 265 265 PHE PHE R . n 
D 4 266 ASN 266 266 266 ASN ASN R . n 
D 4 267 ALA 267 267 267 ALA ALA R . n 
D 4 268 TYR 268 268 268 TYR TYR R . n 
D 4 269 HIS 269 269 269 HIS HIS R . n 
D 4 270 PHE 270 270 270 PHE PHE R . n 
D 4 271 SER 271 271 271 SER SER R . n 
D 4 272 LEU 272 272 272 LEU LEU R . n 
D 4 273 LEU 273 273 273 LEU LEU R . n 
D 4 274 LEU 274 274 274 LEU LEU R . n 
D 4 275 THR 275 275 275 THR THR R . n 
D 4 276 SER 276 276 276 SER SER R . n 
D 4 277 PHE 277 277 277 PHE PHE R . n 
D 4 278 ASN 278 278 278 ASN ASN R . n 
D 4 279 CYS 279 279 279 CYS CYS R . n 
D 4 280 VAL 280 280 280 VAL VAL R . n 
D 4 281 ALA 281 281 281 ALA ALA R . n 
D 4 282 ASP 282 282 282 ASP ASP R . n 
D 4 283 PRO 283 283 283 PRO PRO R . n 
D 4 284 VAL 284 284 284 VAL VAL R . n 
D 4 285 LEU 285 285 285 LEU LEU R . n 
D 4 286 TYR 286 286 286 TYR TYR R . n 
D 4 287 CYS 287 287 287 CYS CYS R . n 
D 4 288 PHE 288 288 288 PHE PHE R . n 
D 4 289 VAL 289 289 289 VAL VAL R . n 
D 4 290 SER 290 290 290 SER SER R . n 
D 4 291 GLU 291 291 291 GLU GLU R . n 
D 4 292 THR 292 292 292 THR THR R . n 
D 4 293 THR 293 293 293 THR THR R . n 
D 4 294 HIS 294 294 294 HIS HIS R . n 
D 4 295 ARG 295 295 295 ARG ARG R . n 
D 4 296 ASP 296 296 296 ASP ASP R . n 
D 4 297 LEU 297 297 297 LEU LEU R . n 
D 4 298 ALA 298 298 ?   ?   ?   R . n 
D 4 299 ARG 299 299 ?   ?   ?   R . n 
D 4 300 LEU 300 300 ?   ?   ?   R . n 
D 4 301 ARG 301 301 ?   ?   ?   R . n 
D 4 302 GLY 302 302 ?   ?   ?   R . n 
D 4 303 ALA 303 303 ?   ?   ?   R . n 
D 4 304 CYS 304 304 ?   ?   ?   R . n 
D 4 305 LEU 305 305 ?   ?   ?   R . n 
D 4 306 ALA 306 306 ?   ?   ?   R . n 
D 4 307 PHE 307 307 ?   ?   ?   R . n 
D 4 308 LEU 308 308 ?   ?   ?   R . n 
D 4 309 THR 309 309 ?   ?   ?   R . n 
D 4 310 CYS 310 310 ?   ?   ?   R . n 
D 4 311 SER 311 311 ?   ?   ?   R . n 
D 4 312 ARG 312 312 ?   ?   ?   R . n 
D 4 313 THR 313 313 ?   ?   ?   R . n 
D 4 314 GLY 314 314 ?   ?   ?   R . n 
D 4 315 ARG 315 315 ?   ?   ?   R . n 
D 4 316 ALA 316 316 ?   ?   ?   R . n 
D 4 317 ARG 317 317 ?   ?   ?   R . n 
D 4 318 GLU 318 318 ?   ?   ?   R . n 
D 4 319 ALA 319 319 ?   ?   ?   R . n 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1   1 Y 1 A LEU 5   ? CG  ? A LEU 6   CG  
2   1 Y 1 A LEU 5   ? CD1 ? A LEU 6   CD1 
3   1 Y 1 A LEU 5   ? CD2 ? A LEU 6   CD2 
4   1 Y 1 A GLU 8   ? CG  ? A GLU 9   CG  
5   1 Y 1 A GLU 8   ? CD  ? A GLU 9   CD  
6   1 Y 1 A GLU 8   ? OE1 ? A GLU 9   OE1 
7   1 Y 1 A GLU 8   ? OE2 ? A GLU 9   OE2 
8   1 Y 1 A ASP 9   ? CG  ? A ASP 10  CG  
9   1 Y 1 A ASP 9   ? OD1 ? A ASP 10  OD1 
10  1 Y 1 A ASP 9   ? OD2 ? A ASP 10  OD2 
11  1 Y 1 A LYS 10  ? CG  ? A LYS 11  CG  
12  1 Y 1 A LYS 10  ? CD  ? A LYS 11  CD  
13  1 Y 1 A LYS 10  ? CE  ? A LYS 11  CE  
14  1 Y 1 A LYS 10  ? NZ  ? A LYS 11  NZ  
15  1 Y 1 A GLU 14  ? CG  ? A GLU 15  CG  
16  1 Y 1 A GLU 14  ? CD  ? A GLU 15  CD  
17  1 Y 1 A GLU 14  ? OE1 ? A GLU 15  OE1 
18  1 Y 1 A GLU 14  ? OE2 ? A GLU 15  OE2 
19  1 Y 1 A MET 18  ? CG  ? A MET 19  CG  
20  1 Y 1 A MET 18  ? SD  ? A MET 19  SD  
21  1 Y 1 A MET 18  ? CE  ? A MET 19  CE  
22  1 Y 1 A GLU 27  ? CG  ? A GLU 21  CG  
23  1 Y 1 A GLU 27  ? CD  ? A GLU 21  CD  
24  1 Y 1 A GLU 27  ? OE1 ? A GLU 21  OE1 
25  1 Y 1 A GLU 27  ? OE2 ? A GLU 21  OE2 
26  1 Y 1 A LYS 28  ? CG  ? A LYS 22  CG  
27  1 Y 1 A LYS 28  ? CD  ? A LYS 22  CD  
28  1 Y 1 A LYS 28  ? CE  ? A LYS 22  CE  
29  1 Y 1 A LYS 28  ? NZ  ? A LYS 22  NZ  
30  1 Y 1 A GLN 31  ? CG  ? A GLN 25  CG  
31  1 Y 1 A GLN 31  ? CD  ? A GLN 25  CD  
32  1 Y 1 A GLN 31  ? OE1 ? A GLN 25  OE1 
33  1 Y 1 A GLN 31  ? NE2 ? A GLN 25  NE2 
34  1 Y 1 A LYS 32  ? CG  ? A LYS 26  CG  
35  1 Y 1 A LYS 32  ? CD  ? A LYS 26  CD  
36  1 Y 1 A LYS 32  ? CE  ? A LYS 26  CE  
37  1 Y 1 A LYS 32  ? NZ  ? A LYS 26  NZ  
38  1 Y 1 A ASP 33  ? CG  ? A ASP 27  CG  
39  1 Y 1 A ASP 33  ? OD1 ? A ASP 27  OD1 
40  1 Y 1 A ASP 33  ? OD2 ? A ASP 27  OD2 
41  1 Y 1 A LYS 34  ? CG  ? A LYS 28  CG  
42  1 Y 1 A LYS 34  ? CD  ? A LYS 28  CD  
43  1 Y 1 A LYS 34  ? CE  ? A LYS 28  CE  
44  1 Y 1 A LYS 34  ? NZ  ? A LYS 28  NZ  
45  1 Y 1 A ASP 49  ? CG  ? A ASP 43  CG  
46  1 Y 1 A ASP 49  ? OD1 ? A ASP 43  OD1 
47  1 Y 1 A ASP 49  ? OD2 ? A ASP 43  OD2 
48  1 Y 1 A ASN 50  ? CG  ? A ASN 44  CG  
49  1 Y 1 A ASN 50  ? OD1 ? A ASN 44  OD1 
50  1 Y 1 A ASN 50  ? ND2 ? A ASN 44  ND2 
51  1 Y 1 A THR 55  ? OG1 ? A THR 49  OG1 
52  1 Y 1 A THR 55  ? CG2 ? A THR 49  CG2 
53  1 Y 1 A LYS 58  ? CG  ? A LYS 52  CG  
54  1 Y 1 A LYS 58  ? CD  ? A LYS 52  CD  
55  1 Y 1 A LYS 58  ? CE  ? A LYS 52  CE  
56  1 Y 1 A LYS 58  ? NZ  ? A LYS 52  NZ  
57  1 Y 1 A GLN 59  ? CG  ? A GLN 53  CG  
58  1 Y 1 A GLN 59  ? CD  ? A GLN 53  CD  
59  1 Y 1 A GLN 59  ? OE1 ? A GLN 53  OE1 
60  1 Y 1 A GLN 59  ? NE2 ? A GLN 53  NE2 
61  1 Y 1 A ARG 61  ? CG  ? A ARG 55  CG  
62  1 Y 1 A ARG 61  ? CD  ? A ARG 55  CD  
63  1 Y 1 A ARG 61  ? NE  ? A ARG 55  NE  
64  1 Y 1 A ARG 61  ? CZ  ? A ARG 55  CZ  
65  1 Y 1 A ARG 61  ? NH1 ? A ARG 55  NH1 
66  1 Y 1 A ARG 61  ? NH2 ? A ARG 55  NH2 
67  1 Y 1 A ILE 62  ? CG1 ? A ILE 56  CG1 
68  1 Y 1 A ILE 62  ? CG2 ? A ILE 56  CG2 
69  1 Y 1 A ILE 62  ? CD1 ? A ILE 56  CD1 
70  1 Y 1 A TYR 63  ? CG  ? A TYR 57  CG  
71  1 Y 1 A TYR 63  ? CD1 ? A TYR 57  CD1 
72  1 Y 1 A TYR 63  ? CD2 ? A TYR 57  CD2 
73  1 Y 1 A TYR 63  ? CE1 ? A TYR 57  CE1 
74  1 Y 1 A TYR 63  ? CE2 ? A TYR 57  CE2 
75  1 Y 1 A TYR 63  ? CZ  ? A TYR 57  CZ  
76  1 Y 1 A TYR 63  ? OH  ? A TYR 57  OH  
77  1 Y 1 A HIS 64  ? CG  ? A HIS 58  CG  
78  1 Y 1 A HIS 64  ? ND1 ? A HIS 58  ND1 
79  1 Y 1 A HIS 64  ? CD2 ? A HIS 58  CD2 
80  1 Y 1 A HIS 64  ? CE1 ? A HIS 58  CE1 
81  1 Y 1 A HIS 64  ? NE2 ? A HIS 58  NE2 
82  1 Y 1 A LYS 213 ? CG  ? A LYS 181 CG  
83  1 Y 1 A LYS 213 ? CD  ? A LYS 181 CD  
84  1 Y 1 A LYS 213 ? CE  ? A LYS 181 CE  
85  1 Y 1 A LYS 213 ? NZ  ? A LYS 181 NZ  
86  1 Y 1 A LYS 226 ? CG  ? A LYS 194 CG  
87  1 Y 1 A LYS 226 ? CD  ? A LYS 194 CD  
88  1 Y 1 A LYS 226 ? CE  ? A LYS 194 CE  
89  1 Y 1 A LYS 226 ? NZ  ? A LYS 194 NZ  
90  1 Y 1 A ASP 233 ? CG  ? A ASP 201 CG  
91  1 Y 1 A ASP 233 ? OD1 ? A ASP 201 OD1 
92  1 Y 1 A ASP 233 ? OD2 ? A ASP 201 OD2 
93  1 Y 1 A ASP 239 ? CG  ? A ASP 207 CG  
94  1 Y 1 A ASP 239 ? OD1 ? A ASP 207 OD1 
95  1 Y 1 A ASP 239 ? OD2 ? A ASP 207 OD2 
96  1 Y 1 A GLU 240 ? CG  ? A GLU 208 CG  
97  1 Y 1 A GLU 240 ? CD  ? A GLU 208 CD  
98  1 Y 1 A GLU 240 ? OE1 ? A GLU 208 OE1 
99  1 Y 1 A GLU 240 ? OE2 ? A GLU 208 OE2 
100 1 Y 1 A ARG 242 ? CG  ? A ARG 210 CG  
101 1 Y 1 A ARG 242 ? CD  ? A ARG 210 CD  
102 1 Y 1 A ARG 242 ? NE  ? A ARG 210 NE  
103 1 Y 1 A ARG 242 ? CZ  ? A ARG 210 CZ  
104 1 Y 1 A ARG 242 ? NH1 ? A ARG 210 NH1 
105 1 Y 1 A ARG 242 ? NH2 ? A ARG 210 NH2 
106 1 Y 1 A ASP 250 ? CG  ? A ASP 218 CG  
107 1 Y 1 A ASP 250 ? OD1 ? A ASP 218 OD1 
108 1 Y 1 A ASP 250 ? OD2 ? A ASP 218 OD2 
109 1 Y 1 A ASP 262 ? CG  ? A ASP 230 CG  
110 1 Y 1 A ASP 262 ? OD1 ? A ASP 230 OD1 
111 1 Y 1 A ASP 262 ? OD2 ? A ASP 230 OD2 
112 1 Y 1 A ASN 264 ? CG  ? A ASN 232 CG  
113 1 Y 1 A ASN 264 ? OD1 ? A ASN 232 OD1 
114 1 Y 1 A ASN 264 ? ND2 ? A ASN 232 ND2 
115 1 Y 1 A GLU 268 ? CG  ? A GLU 236 CG  
116 1 Y 1 A GLU 268 ? CD  ? A GLU 236 CD  
117 1 Y 1 A GLU 268 ? OE1 ? A GLU 236 OE1 
118 1 Y 1 A GLU 268 ? OE2 ? A GLU 236 OE2 
119 1 Y 1 A ARG 280 ? CG  ? A ARG 248 CG  
120 1 Y 1 A ARG 280 ? CD  ? A ARG 248 CD  
121 1 Y 1 A ARG 280 ? NE  ? A ARG 248 NE  
122 1 Y 1 A ARG 280 ? CZ  ? A ARG 248 CZ  
123 1 Y 1 A ARG 280 ? NH1 ? A ARG 248 NH1 
124 1 Y 1 A ARG 280 ? NH2 ? A ARG 248 NH2 
125 1 Y 1 A ARG 283 ? CG  ? A ARG 251 CG  
126 1 Y 1 A ARG 283 ? CD  ? A ARG 251 CD  
127 1 Y 1 A ARG 283 ? NE  ? A ARG 251 NE  
128 1 Y 1 A ARG 283 ? CZ  ? A ARG 251 CZ  
129 1 Y 1 A ARG 283 ? NH1 ? A ARG 251 NH1 
130 1 Y 1 A ARG 283 ? NH2 ? A ARG 251 NH2 
131 1 Y 1 A ASP 295 ? CG  ? A ASP 263 CG  
132 1 Y 1 A ASP 295 ? OD1 ? A ASP 263 OD1 
133 1 Y 1 A ASP 295 ? OD2 ? A ASP 263 OD2 
134 1 Y 1 A GLU 299 ? CG  ? A GLU 267 CG  
135 1 Y 1 A GLU 299 ? CD  ? A GLU 267 CD  
136 1 Y 1 A GLU 299 ? OE1 ? A GLU 267 OE1 
137 1 Y 1 A GLU 299 ? OE2 ? A GLU 267 OE2 
138 1 Y 1 A VAL 301 ? CG1 ? A VAL 269 CG1 
139 1 Y 1 A VAL 301 ? CG2 ? A VAL 269 CG2 
140 1 Y 1 A LYS 305 ? CG  ? A LYS 273 CG  
141 1 Y 1 A LYS 305 ? CD  ? A LYS 273 CD  
142 1 Y 1 A LYS 305 ? CE  ? A LYS 273 CE  
143 1 Y 1 A LYS 305 ? NZ  ? A LYS 273 NZ  
144 1 Y 1 A LYS 307 ? CG  ? A LYS 275 CG  
145 1 Y 1 A LYS 307 ? CD  ? A LYS 275 CD  
146 1 Y 1 A LYS 307 ? CE  ? A LYS 275 CE  
147 1 Y 1 A LYS 307 ? NZ  ? A LYS 275 NZ  
148 1 Y 1 A GLU 309 ? CG  ? A GLU 277 CG  
149 1 Y 1 A GLU 309 ? CD  ? A GLU 277 CD  
150 1 Y 1 A GLU 309 ? OE1 ? A GLU 277 OE1 
151 1 Y 1 A GLU 309 ? OE2 ? A GLU 277 OE2 
152 1 Y 1 A ASP 310 ? CG  ? A ASP 278 CG  
153 1 Y 1 A ASP 310 ? OD1 ? A ASP 278 OD1 
154 1 Y 1 A ASP 310 ? OD2 ? A ASP 278 OD2 
155 1 Y 1 A GLU 314 ? CG  ? A GLU 282 CG  
156 1 Y 1 A GLU 314 ? CD  ? A GLU 282 CD  
157 1 Y 1 A GLU 314 ? OE1 ? A GLU 282 OE1 
158 1 Y 1 A GLU 314 ? OE2 ? A GLU 282 OE2 
159 1 Y 1 A ARG 317 ? CG  ? A ARG 285 CG  
160 1 Y 1 A ARG 317 ? CD  ? A ARG 285 CD  
161 1 Y 1 A ARG 317 ? NE  ? A ARG 285 NE  
162 1 Y 1 A ARG 317 ? CZ  ? A ARG 285 CZ  
163 1 Y 1 A ARG 317 ? NH1 ? A ARG 285 NH1 
164 1 Y 1 A ARG 317 ? NH2 ? A ARG 285 NH2 
165 1 Y 1 A GLU 322 ? CG  ? A GLU 290 CG  
166 1 Y 1 A GLU 322 ? CD  ? A GLU 290 CD  
167 1 Y 1 A GLU 322 ? OE1 ? A GLU 290 OE1 
168 1 Y 1 A GLU 322 ? OE2 ? A GLU 290 OE2 
169 1 Y 1 A ASP 323 ? CG  ? A ASP 291 CG  
170 1 Y 1 A ASP 323 ? OD1 ? A ASP 291 OD1 
171 1 Y 1 A ASP 323 ? OD2 ? A ASP 291 OD2 
172 1 Y 1 A GLU 327 ? CG  ? A GLU 295 CG  
173 1 Y 1 A GLU 327 ? CD  ? A GLU 295 CD  
174 1 Y 1 A GLU 327 ? OE1 ? A GLU 295 OE1 
175 1 Y 1 A GLU 327 ? OE2 ? A GLU 295 OE2 
176 1 Y 1 A GLU 330 ? CG  ? A GLU 298 CG  
177 1 Y 1 A GLU 330 ? CD  ? A GLU 298 CD  
178 1 Y 1 A GLU 330 ? OE1 ? A GLU 298 OE1 
179 1 Y 1 A GLU 330 ? OE2 ? A GLU 298 OE2 
180 1 Y 1 A ASP 331 ? CG  ? A ASP 299 CG  
181 1 Y 1 A ASP 331 ? OD1 ? A ASP 299 OD1 
182 1 Y 1 A ASP 331 ? OD2 ? A ASP 299 OD2 
183 1 Y 1 A ASP 343 ? CG  ? A ASP 311 CG  
184 1 Y 1 A ASP 343 ? OD1 ? A ASP 311 OD1 
185 1 Y 1 A ASP 343 ? OD2 ? A ASP 311 OD2 
186 1 Y 1 A ASP 354 ? CG  ? A ASP 322 CG  
187 1 Y 1 A ASP 354 ? OD1 ? A ASP 322 OD1 
188 1 Y 1 A ASP 354 ? OD2 ? A ASP 322 OD2 
189 1 Y 1 A ARG 356 ? CG  ? A ARG 324 CG  
190 1 Y 1 A ARG 356 ? CD  ? A ARG 324 CD  
191 1 Y 1 A ARG 356 ? NE  ? A ARG 324 NE  
192 1 Y 1 A ARG 356 ? CZ  ? A ARG 324 CZ  
193 1 Y 1 A ARG 356 ? NH1 ? A ARG 324 NH1 
194 1 Y 1 A ARG 356 ? NH2 ? A ARG 324 NH2 
195 1 Y 1 A ASP 368 ? CG  ? A ASP 336 CG  
196 1 Y 1 A ASP 368 ? OD1 ? A ASP 336 OD1 
197 1 Y 1 A ASP 368 ? OD2 ? A ASP 336 OD2 
198 1 Y 1 A GLU 370 ? CG  ? A GLU 338 CG  
199 1 Y 1 A GLU 370 ? CD  ? A GLU 338 CD  
200 1 Y 1 A GLU 370 ? OE1 ? A GLU 338 OE1 
201 1 Y 1 A GLU 370 ? OE2 ? A GLU 338 OE2 
202 1 Y 1 A ASP 378 ? CG  ? A ASP 346 CG  
203 1 Y 1 A ASP 378 ? OD1 ? A ASP 346 OD1 
204 1 Y 1 A ASP 378 ? OD2 ? A ASP 346 OD2 
205 1 Y 1 A ARG 389 ? CG  ? A ARG 357 CG  
206 1 Y 1 A ARG 389 ? CD  ? A ARG 357 CD  
207 1 Y 1 A ARG 389 ? NE  ? A ARG 357 NE  
208 1 Y 1 A ARG 389 ? CZ  ? A ARG 357 CZ  
209 1 Y 1 A ARG 389 ? NH1 ? A ARG 357 NH1 
210 1 Y 1 A ARG 389 ? NH2 ? A ARG 357 NH2 
211 1 Y 1 B GLU 3   ? CG  ? B GLU 8   CG  
212 1 Y 1 B GLU 3   ? CD  ? B GLU 8   CD  
213 1 Y 1 B GLU 3   ? OE1 ? B GLU 8   OE1 
214 1 Y 1 B GLU 3   ? OE2 ? B GLU 8   OE2 
215 1 Y 1 B LEU 4   ? CG  ? B LEU 9   CG  
216 1 Y 1 B LEU 4   ? CD1 ? B LEU 9   CD1 
217 1 Y 1 B LEU 4   ? CD2 ? B LEU 9   CD2 
218 1 Y 1 B ASP 5   ? CG  ? B ASP 10  CG  
219 1 Y 1 B ASP 5   ? OD1 ? B ASP 10  OD1 
220 1 Y 1 B ASP 5   ? OD2 ? B ASP 10  OD2 
221 1 Y 1 B GLN 6   ? CG  ? B GLN 11  CG  
222 1 Y 1 B GLN 6   ? CD  ? B GLN 11  CD  
223 1 Y 1 B GLN 6   ? OE1 ? B GLN 11  OE1 
224 1 Y 1 B GLN 6   ? NE2 ? B GLN 11  NE2 
225 1 Y 1 B LEU 7   ? CG  ? B LEU 12  CG  
226 1 Y 1 B LEU 7   ? CD1 ? B LEU 12  CD1 
227 1 Y 1 B LEU 7   ? CD2 ? B LEU 12  CD2 
228 1 Y 1 B ARG 8   ? CG  ? B ARG 13  CG  
229 1 Y 1 B ARG 8   ? CD  ? B ARG 13  CD  
230 1 Y 1 B ARG 8   ? NE  ? B ARG 13  NE  
231 1 Y 1 B ARG 8   ? CZ  ? B ARG 13  CZ  
232 1 Y 1 B ARG 8   ? NH1 ? B ARG 13  NH1 
233 1 Y 1 B ARG 8   ? NH2 ? B ARG 13  NH2 
234 1 Y 1 B GLN 9   ? CG  ? B GLN 14  CG  
235 1 Y 1 B GLN 9   ? CD  ? B GLN 14  CD  
236 1 Y 1 B GLN 9   ? OE1 ? B GLN 14  OE1 
237 1 Y 1 B GLN 9   ? NE2 ? B GLN 14  NE2 
238 1 Y 1 B GLU 10  ? CG  ? B GLU 15  CG  
239 1 Y 1 B GLU 10  ? CD  ? B GLU 15  CD  
240 1 Y 1 B GLU 10  ? OE1 ? B GLU 15  OE1 
241 1 Y 1 B GLU 10  ? OE2 ? B GLU 15  OE2 
242 1 Y 1 B GLU 12  ? CG  ? B GLU 17  CG  
243 1 Y 1 B GLU 12  ? CD  ? B GLU 17  CD  
244 1 Y 1 B GLU 12  ? OE1 ? B GLU 17  OE1 
245 1 Y 1 B GLU 12  ? OE2 ? B GLU 17  OE2 
246 1 Y 1 B GLN 13  ? CG  ? B GLN 18  CG  
247 1 Y 1 B GLN 13  ? CD  ? B GLN 18  CD  
248 1 Y 1 B GLN 13  ? OE1 ? B GLN 18  OE1 
249 1 Y 1 B GLN 13  ? NE2 ? B GLN 18  NE2 
250 1 Y 1 B LYS 15  ? CG  ? B LYS 20  CG  
251 1 Y 1 B LYS 15  ? CD  ? B LYS 20  CD  
252 1 Y 1 B LYS 15  ? CE  ? B LYS 20  CE  
253 1 Y 1 B LYS 15  ? NZ  ? B LYS 20  NZ  
254 1 Y 1 B ASN 16  ? CG  ? B ASN 21  CG  
255 1 Y 1 B ASN 16  ? OD1 ? B ASN 21  OD1 
256 1 Y 1 B ASN 16  ? ND2 ? B ASN 21  ND2 
257 1 Y 1 B ARG 19  ? CG  ? B ARG 24  CG  
258 1 Y 1 B ARG 19  ? CD  ? B ARG 24  CD  
259 1 Y 1 B ARG 19  ? NE  ? B ARG 24  NE  
260 1 Y 1 B ARG 19  ? CZ  ? B ARG 24  CZ  
261 1 Y 1 B ARG 19  ? NH1 ? B ARG 24  NH1 
262 1 Y 1 B ARG 19  ? NH2 ? B ARG 24  NH2 
263 1 Y 1 B ASP 20  ? CG  ? B ASP 25  CG  
264 1 Y 1 B ASP 20  ? OD1 ? B ASP 25  OD1 
265 1 Y 1 B ASP 20  ? OD2 ? B ASP 25  OD2 
266 1 Y 1 B LYS 23  ? CG  ? B LYS 28  CG  
267 1 Y 1 B LYS 23  ? CD  ? B LYS 28  CD  
268 1 Y 1 B LYS 23  ? CE  ? B LYS 28  CE  
269 1 Y 1 B LYS 23  ? NZ  ? B LYS 28  NZ  
270 1 Y 1 B THR 29  ? OG1 ? B THR 34  OG1 
271 1 Y 1 B THR 29  ? CG2 ? B THR 34  CG2 
272 1 Y 1 B ASN 36  ? CG  ? B ASN 41  CG  
273 1 Y 1 B ASN 36  ? OD1 ? B ASN 41  OD1 
274 1 Y 1 B ASN 36  ? ND2 ? B ASN 41  ND2 
275 1 Y 1 B ASP 38  ? CG  ? B ASP 43  CG  
276 1 Y 1 B ASP 38  ? OD1 ? B ASP 43  OD1 
277 1 Y 1 B ASP 38  ? OD2 ? B ASP 43  OD2 
278 1 Y 1 B ARG 42  ? CG  ? B ARG 47  CG  
279 1 Y 1 B ARG 42  ? CD  ? B ARG 47  CD  
280 1 Y 1 B ARG 42  ? NE  ? B ARG 47  NE  
281 1 Y 1 B ARG 42  ? CZ  ? B ARG 47  CZ  
282 1 Y 1 B ARG 42  ? NH1 ? B ARG 47  NH1 
283 1 Y 1 B ARG 42  ? NH2 ? B ARG 47  NH2 
284 1 Y 1 B GLN 44  ? CG  ? B GLN 49  CG  
285 1 Y 1 B GLN 44  ? CD  ? B GLN 49  CD  
286 1 Y 1 B GLN 44  ? OE1 ? B GLN 49  OE1 
287 1 Y 1 B GLN 44  ? NE2 ? B GLN 49  NE2 
288 1 Y 1 B ARG 46  ? CG  ? B ARG 51  CG  
289 1 Y 1 B ARG 46  ? CD  ? B ARG 51  CD  
290 1 Y 1 B ARG 46  ? NE  ? B ARG 51  NE  
291 1 Y 1 B ARG 46  ? CZ  ? B ARG 51  CZ  
292 1 Y 1 B ARG 46  ? NH1 ? B ARG 51  NH1 
293 1 Y 1 B ARG 46  ? NH2 ? B ARG 51  NH2 
294 1 Y 1 B ARG 52  ? CG  ? B ARG 57  CG  
295 1 Y 1 B ARG 52  ? CD  ? B ARG 57  CD  
296 1 Y 1 B ARG 52  ? NE  ? B ARG 57  NE  
297 1 Y 1 B ARG 52  ? CZ  ? B ARG 57  CZ  
298 1 Y 1 B ARG 52  ? NH1 ? B ARG 57  NH1 
299 1 Y 1 B ARG 52  ? NH2 ? B ARG 57  NH2 
300 1 Y 1 B ARG 96  ? CG  ? B ARG 101 CG  
301 1 Y 1 B ARG 96  ? CD  ? B ARG 101 CD  
302 1 Y 1 B ARG 96  ? NE  ? B ARG 101 NE  
303 1 Y 1 B ARG 96  ? CZ  ? B ARG 101 CZ  
304 1 Y 1 B ARG 96  ? NH1 ? B ARG 101 NH1 
305 1 Y 1 B ARG 96  ? NH2 ? B ARG 101 NH2 
306 1 Y 1 B ARG 129 ? CG  ? B ARG 134 CG  
307 1 Y 1 B ARG 129 ? CD  ? B ARG 134 CD  
308 1 Y 1 B ARG 129 ? NE  ? B ARG 134 NE  
309 1 Y 1 B ARG 129 ? CZ  ? B ARG 134 CZ  
310 1 Y 1 B ARG 129 ? NH1 ? B ARG 134 NH1 
311 1 Y 1 B ARG 129 ? NH2 ? B ARG 134 NH2 
312 1 Y 1 B GLU 172 ? CG  ? B GLU 177 CG  
313 1 Y 1 B GLU 172 ? CD  ? B GLU 177 CD  
314 1 Y 1 B GLU 172 ? OE1 ? B GLU 177 OE1 
315 1 Y 1 B GLU 172 ? OE2 ? B GLU 177 OE2 
316 1 Y 1 B THR 173 ? OG1 ? B THR 178 OG1 
317 1 Y 1 B THR 173 ? CG2 ? B THR 178 CG2 
318 1 Y 1 B GLN 175 ? CG  ? B GLN 180 CG  
319 1 Y 1 B GLN 175 ? CD  ? B GLN 180 CD  
320 1 Y 1 B GLN 175 ? OE1 ? B GLN 180 OE1 
321 1 Y 1 B GLN 175 ? NE2 ? B GLN 180 NE2 
322 1 Y 1 B ARG 197 ? CG  ? B ARG 202 CG  
323 1 Y 1 B ARG 197 ? CD  ? B ARG 202 CD  
324 1 Y 1 B ARG 197 ? NE  ? B ARG 202 NE  
325 1 Y 1 B ARG 197 ? CZ  ? B ARG 202 CZ  
326 1 Y 1 B ARG 197 ? NH1 ? B ARG 202 NH1 
327 1 Y 1 B ARG 197 ? NH2 ? B ARG 202 NH2 
328 1 Y 1 B ARG 214 ? CG  ? B ARG 219 CG  
329 1 Y 1 B ARG 214 ? CD  ? B ARG 219 CD  
330 1 Y 1 B ARG 214 ? NE  ? B ARG 219 NE  
331 1 Y 1 B ARG 214 ? CZ  ? B ARG 219 CZ  
332 1 Y 1 B ARG 214 ? NH1 ? B ARG 219 NH1 
333 1 Y 1 B ARG 214 ? NH2 ? B ARG 219 NH2 
334 1 Y 1 B GLU 215 ? CG  ? B GLU 220 CG  
335 1 Y 1 B GLU 215 ? CD  ? B GLU 220 CD  
336 1 Y 1 B GLU 215 ? OE1 ? B GLU 220 OE1 
337 1 Y 1 B GLU 215 ? OE2 ? B GLU 220 OE2 
338 1 Y 1 B MET 217 ? CG  ? B MET 222 CG  
339 1 Y 1 B MET 217 ? SD  ? B MET 222 SD  
340 1 Y 1 B MET 217 ? CE  ? B MET 222 CE  
341 1 Y 1 B GLU 226 ? CG  ? B GLU 231 CG  
342 1 Y 1 B GLU 226 ? CD  ? B GLU 231 CD  
343 1 Y 1 B GLU 226 ? OE1 ? B GLU 231 OE1 
344 1 Y 1 B GLU 226 ? OE2 ? B GLU 231 OE2 
345 1 Y 1 B ILE 273 ? CG1 ? B ILE 278 CG1 
346 1 Y 1 B ILE 273 ? CG2 ? B ILE 278 CG2 
347 1 Y 1 B ILE 273 ? CD1 ? B ILE 278 CD1 
348 1 Y 1 B ASN 293 ? CG  ? B ASN 298 CG  
349 1 Y 1 B ASN 293 ? OD1 ? B ASN 298 OD1 
350 1 Y 1 B ASN 293 ? ND2 ? B ASN 298 ND2 
351 1 Y 1 B LYS 301 ? CG  ? B LYS 306 CG  
352 1 Y 1 B LYS 301 ? CD  ? B LYS 306 CD  
353 1 Y 1 B LYS 301 ? CE  ? B LYS 306 CE  
354 1 Y 1 B LYS 301 ? NZ  ? B LYS 306 NZ  
355 1 Y 1 B ASP 303 ? CG  ? B ASP 308 CG  
356 1 Y 1 B ASP 303 ? OD1 ? B ASP 308 OD1 
357 1 Y 1 B ASP 303 ? OD2 ? B ASP 308 OD2 
358 1 Y 1 B ASP 312 ? CG  ? B ASP 317 CG  
359 1 Y 1 B ASP 312 ? OD1 ? B ASP 317 OD1 
360 1 Y 1 B ASP 312 ? OD2 ? B ASP 317 OD2 
361 1 Y 1 G GLN 11  ? CG  ? C GLN 11  CG  
362 1 Y 1 G GLN 11  ? CD  ? C GLN 11  CD  
363 1 Y 1 G GLN 11  ? OE1 ? C GLN 11  OE1 
364 1 Y 1 G GLN 11  ? NE2 ? C GLN 11  NE2 
365 1 Y 1 G ARG 13  ? CG  ? C ARG 13  CG  
366 1 Y 1 G ARG 13  ? CD  ? C ARG 13  CD  
367 1 Y 1 G ARG 13  ? NE  ? C ARG 13  NE  
368 1 Y 1 G ARG 13  ? CZ  ? C ARG 13  CZ  
369 1 Y 1 G ARG 13  ? NH1 ? C ARG 13  NH1 
370 1 Y 1 G ARG 13  ? NH2 ? C ARG 13  NH2 
371 1 Y 1 G LYS 14  ? CG  ? C LYS 14  CG  
372 1 Y 1 G LYS 14  ? CD  ? C LYS 14  CD  
373 1 Y 1 G LYS 14  ? CE  ? C LYS 14  CE  
374 1 Y 1 G LYS 14  ? NZ  ? C LYS 14  NZ  
375 1 Y 1 G LEU 15  ? CG  ? C LEU 15  CG  
376 1 Y 1 G LEU 15  ? CD1 ? C LEU 15  CD1 
377 1 Y 1 G LEU 15  ? CD2 ? C LEU 15  CD2 
378 1 Y 1 G GLU 17  ? CG  ? C GLU 17  CG  
379 1 Y 1 G GLU 17  ? CD  ? C GLU 17  CD  
380 1 Y 1 G GLU 17  ? OE1 ? C GLU 17  OE1 
381 1 Y 1 G GLU 17  ? OE2 ? C GLU 17  OE2 
382 1 Y 1 G LYS 20  ? CG  ? C LYS 20  CG  
383 1 Y 1 G LYS 20  ? CD  ? C LYS 20  CD  
384 1 Y 1 G LYS 20  ? CE  ? C LYS 20  CE  
385 1 Y 1 G LYS 20  ? NZ  ? C LYS 20  NZ  
386 1 Y 1 G MET 21  ? CG  ? C MET 21  CG  
387 1 Y 1 G MET 21  ? SD  ? C MET 21  SD  
388 1 Y 1 G MET 21  ? CE  ? C MET 21  CE  
389 1 Y 1 G GLU 22  ? CG  ? C GLU 22  CG  
390 1 Y 1 G GLU 22  ? CD  ? C GLU 22  CD  
391 1 Y 1 G GLU 22  ? OE1 ? C GLU 22  OE1 
392 1 Y 1 G GLU 22  ? OE2 ? C GLU 22  OE2 
393 1 Y 1 G ASN 24  ? CG  ? C ASN 24  CG  
394 1 Y 1 G ASN 24  ? OD1 ? C ASN 24  OD1 
395 1 Y 1 G ASN 24  ? ND2 ? C ASN 24  ND2 
396 1 Y 1 G ILE 25  ? CG1 ? C ILE 25  CG1 
397 1 Y 1 G ILE 25  ? CG2 ? C ILE 25  CG2 
398 1 Y 1 G ILE 25  ? CD1 ? C ILE 25  CD1 
399 1 Y 1 G ASP 26  ? CG  ? C ASP 26  CG  
400 1 Y 1 G ASP 26  ? OD1 ? C ASP 26  OD1 
401 1 Y 1 G ASP 26  ? OD2 ? C ASP 26  OD2 
402 1 Y 1 G ARG 27  ? CG  ? C ARG 27  CG  
403 1 Y 1 G ARG 27  ? CD  ? C ARG 27  CD  
404 1 Y 1 G ARG 27  ? NE  ? C ARG 27  NE  
405 1 Y 1 G ARG 27  ? CZ  ? C ARG 27  CZ  
406 1 Y 1 G ARG 27  ? NH1 ? C ARG 27  NH1 
407 1 Y 1 G ARG 27  ? NH2 ? C ARG 27  NH2 
408 1 Y 1 G LYS 29  ? CG  ? C LYS 29  CG  
409 1 Y 1 G LYS 29  ? CD  ? C LYS 29  CD  
410 1 Y 1 G LYS 29  ? CE  ? C LYS 29  CE  
411 1 Y 1 G LYS 29  ? NZ  ? C LYS 29  NZ  
412 1 Y 1 G LYS 32  ? CG  ? C LYS 32  CG  
413 1 Y 1 G LYS 32  ? CD  ? C LYS 32  CD  
414 1 Y 1 G LYS 32  ? CE  ? C LYS 32  CE  
415 1 Y 1 G LYS 32  ? NZ  ? C LYS 32  NZ  
416 1 Y 1 G ASP 36  ? CG  ? C ASP 36  CG  
417 1 Y 1 G ASP 36  ? OD1 ? C ASP 36  OD1 
418 1 Y 1 G ASP 36  ? OD2 ? C ASP 36  OD2 
419 1 Y 1 G MET 38  ? CG  ? C MET 38  CG  
420 1 Y 1 G MET 38  ? SD  ? C MET 38  SD  
421 1 Y 1 G MET 38  ? CE  ? C MET 38  CE  
422 1 Y 1 G GLU 42  ? CG  ? C GLU 42  CG  
423 1 Y 1 G GLU 42  ? CD  ? C GLU 42  CD  
424 1 Y 1 G GLU 42  ? OE1 ? C GLU 42  OE1 
425 1 Y 1 G GLU 42  ? OE2 ? C GLU 42  OE2 
426 1 Y 1 G LYS 46  ? CG  ? C LYS 46  CG  
427 1 Y 1 G LYS 46  ? CD  ? C LYS 46  CD  
428 1 Y 1 G LYS 46  ? CE  ? C LYS 46  CE  
429 1 Y 1 G LYS 46  ? NZ  ? C LYS 46  NZ  
430 1 Y 1 G THR 52  ? OG1 ? C THR 52  OG1 
431 1 Y 1 G THR 52  ? CG2 ? C THR 52  CG2 
432 1 Y 1 G VAL 54  ? CG1 ? C VAL 54  CG1 
433 1 Y 1 G VAL 54  ? CG2 ? C VAL 54  CG2 
434 1 Y 1 G GLU 58  ? CG  ? C GLU 58  CG  
435 1 Y 1 G GLU 58  ? CD  ? C GLU 58  CD  
436 1 Y 1 G GLU 58  ? OE1 ? C GLU 58  OE1 
437 1 Y 1 G GLU 58  ? OE2 ? C GLU 58  OE2 
438 1 Y 1 R THR 14  ? OG1 ? D THR 14  OG1 
439 1 Y 1 R THR 14  ? CG2 ? D THR 14  CG2 
440 1 Y 1 R ILE 15  ? CG1 ? D ILE 15  CG1 
441 1 Y 1 R ILE 15  ? CG2 ? D ILE 15  CG2 
442 1 Y 1 R ILE 15  ? CD1 ? D ILE 15  CD1 
443 1 Y 1 R THR 18  ? OG1 ? D THR 18  OG1 
444 1 Y 1 R THR 18  ? CG2 ? D THR 18  CG2 
445 1 Y 1 R ILE 19  ? CG1 ? D ILE 19  CG1 
446 1 Y 1 R ILE 19  ? CG2 ? D ILE 19  CG2 
447 1 Y 1 R ILE 19  ? CD1 ? D ILE 19  CD1 
448 1 Y 1 R GLN 21  ? CG  ? D GLN 21  CG  
449 1 Y 1 R GLN 21  ? CD  ? D GLN 21  CD  
450 1 Y 1 R GLN 21  ? OE1 ? D GLN 21  OE1 
451 1 Y 1 R GLN 21  ? NE2 ? D GLN 21  NE2 
452 1 Y 1 R THR 22  ? OG1 ? D THR 22  OG1 
453 1 Y 1 R THR 22  ? CG2 ? D THR 22  CG2 
454 1 Y 1 R LEU 23  ? CG  ? D LEU 23  CG  
455 1 Y 1 R LEU 23  ? CD1 ? D LEU 23  CD1 
456 1 Y 1 R LEU 23  ? CD2 ? D LEU 23  CD2 
457 1 Y 1 R VAL 26  ? CG1 ? D VAL 26  CG1 
458 1 Y 1 R VAL 26  ? CG2 ? D VAL 26  CG2 
459 1 Y 1 R THR 30  ? OG1 ? D THR 30  OG1 
460 1 Y 1 R THR 30  ? CG2 ? D THR 30  CG2 
461 1 Y 1 R LYS 51  ? CG  ? D LYS 51  CG  
462 1 Y 1 R LYS 51  ? CD  ? D LYS 51  CD  
463 1 Y 1 R LYS 51  ? CE  ? D LYS 51  CE  
464 1 Y 1 R LYS 51  ? NZ  ? D LYS 51  NZ  
465 1 Y 1 R ARG 53  ? CG  ? D ARG 53  CG  
466 1 Y 1 R ARG 53  ? CD  ? D ARG 53  CD  
467 1 Y 1 R ARG 53  ? NE  ? D ARG 53  NE  
468 1 Y 1 R ARG 53  ? CZ  ? D ARG 53  CZ  
469 1 Y 1 R ARG 53  ? NH1 ? D ARG 53  NH1 
470 1 Y 1 R ARG 53  ? NH2 ? D ARG 53  NH2 
471 1 Y 1 R GLU 55  ? CG  ? D GLU 55  CG  
472 1 Y 1 R GLU 55  ? CD  ? D GLU 55  CD  
473 1 Y 1 R GLU 55  ? OE1 ? D GLU 55  OE1 
474 1 Y 1 R GLU 55  ? OE2 ? D GLU 55  OE2 
475 1 Y 1 R GLN 79  ? CG  ? D GLN 79  CG  
476 1 Y 1 R GLN 79  ? CD  ? D GLN 79  CD  
477 1 Y 1 R GLN 79  ? OE1 ? D GLN 79  OE1 
478 1 Y 1 R GLN 79  ? NE2 ? D GLN 79  NE2 
479 1 Y 1 R ASN 86  ? CG  ? D ASN 86  CG  
480 1 Y 1 R ASN 86  ? OD1 ? D ASN 86  OD1 
481 1 Y 1 R ASN 86  ? ND2 ? D ASN 86  ND2 
482 1 Y 1 R SER 88  ? OG  ? D SER 88  OG  
483 1 Y 1 R ASP 91  ? CG  ? D ASP 91  CG  
484 1 Y 1 R ASP 91  ? OD1 ? D ASP 91  OD1 
485 1 Y 1 R ASP 91  ? OD2 ? D ASP 91  OD2 
486 1 Y 1 R LEU 92  ? CG  ? D LEU 92  CG  
487 1 Y 1 R LEU 92  ? CD1 ? D LEU 92  CD1 
488 1 Y 1 R LEU 92  ? CD2 ? D LEU 92  CD2 
489 1 Y 1 R CYS 94  ? SG  ? D CYS 94  SG  
490 1 Y 1 R GLN 95  ? CG  ? D GLN 95  CG  
491 1 Y 1 R GLN 95  ? CD  ? D GLN 95  CD  
492 1 Y 1 R GLN 95  ? OE1 ? D GLN 95  OE1 
493 1 Y 1 R GLN 95  ? NE2 ? D GLN 95  NE2 
494 1 Y 1 R GLU 103 ? CG  ? D GLU 103 CG  
495 1 Y 1 R GLU 103 ? CD  ? D GLU 103 CD  
496 1 Y 1 R GLU 103 ? OE1 ? D GLU 103 OE1 
497 1 Y 1 R GLU 103 ? OE2 ? D GLU 103 OE2 
498 1 Y 1 R ASN 104 ? CG  ? D ASN 104 CG  
499 1 Y 1 R ASN 104 ? OD1 ? D ASN 104 OD1 
500 1 Y 1 R ASN 104 ? ND2 ? D ASN 104 ND2 
501 1 Y 1 R SER 116 ? OG  ? D SER 116 OG  
502 1 Y 1 R LYS 136 ? CG  ? D LYS 136 CG  
503 1 Y 1 R LYS 136 ? CD  ? D LYS 136 CD  
504 1 Y 1 R LYS 136 ? CE  ? D LYS 136 CE  
505 1 Y 1 R LYS 136 ? NZ  ? D LYS 136 NZ  
506 1 Y 1 R LYS 148 ? CG  ? D LYS 148 CG  
507 1 Y 1 R LYS 148 ? CD  ? D LYS 148 CD  
508 1 Y 1 R LYS 148 ? CE  ? D LYS 148 CE  
509 1 Y 1 R LYS 148 ? NZ  ? D LYS 148 NZ  
510 1 Y 1 R LEU 150 ? CG  ? D LEU 150 CG  
511 1 Y 1 R LEU 150 ? CD1 ? D LEU 150 CD1 
512 1 Y 1 R LEU 150 ? CD2 ? D LEU 150 CD2 
513 1 Y 1 R ILE 154 ? CG1 ? D ILE 154 CG1 
514 1 Y 1 R ILE 154 ? CG2 ? D ILE 154 CG2 
515 1 Y 1 R ILE 154 ? CD1 ? D ILE 154 CD1 
516 1 Y 1 R MET 158 ? CG  ? D MET 158 CG  
517 1 Y 1 R MET 158 ? SD  ? D MET 158 SD  
518 1 Y 1 R MET 158 ? CE  ? D MET 158 CE  
519 1 Y 1 R GLU 160 ? CG  ? D GLU 160 CG  
520 1 Y 1 R GLU 160 ? CD  ? D GLU 160 CD  
521 1 Y 1 R GLU 160 ? OE1 ? D GLU 160 OE1 
522 1 Y 1 R GLU 160 ? OE2 ? D GLU 160 OE2 
523 1 Y 1 R ILE 163 ? CG1 ? D ILE 163 CG1 
524 1 Y 1 R ILE 163 ? CG2 ? D ILE 163 CG2 
525 1 Y 1 R ILE 163 ? CD1 ? D ILE 163 CD1 
526 1 Y 1 R GLU 164 ? CG  ? D GLU 164 CG  
527 1 Y 1 R GLU 164 ? CD  ? D GLU 164 CD  
528 1 Y 1 R GLU 164 ? OE1 ? D GLU 164 OE1 
529 1 Y 1 R GLU 164 ? OE2 ? D GLU 164 OE2 
530 1 Y 1 R ASP 165 ? CG  ? D ASP 165 CG  
531 1 Y 1 R ASP 165 ? OD1 ? D ASP 165 OD1 
532 1 Y 1 R ASP 165 ? OD2 ? D ASP 165 OD2 
533 1 Y 1 R GLU 166 ? CG  ? D GLU 166 CG  
534 1 Y 1 R GLU 166 ? CD  ? D GLU 166 CD  
535 1 Y 1 R GLU 166 ? OE1 ? D GLU 166 OE1 
536 1 Y 1 R GLU 166 ? OE2 ? D GLU 166 OE2 
537 1 Y 1 R ASN 167 ? CG  ? D ASN 167 CG  
538 1 Y 1 R ASN 167 ? OD1 ? D ASN 167 OD1 
539 1 Y 1 R ASN 167 ? ND2 ? D ASN 167 ND2 
540 1 Y 1 R GLN 168 ? CG  ? D GLN 168 CG  
541 1 Y 1 R GLN 168 ? CD  ? D GLN 168 CD  
542 1 Y 1 R GLN 168 ? OE1 ? D GLN 168 OE1 
543 1 Y 1 R GLN 168 ? NE2 ? D GLN 168 NE2 
544 1 Y 1 R ARG 170 ? CG  ? D ARG 170 CG  
545 1 Y 1 R ARG 170 ? CD  ? D ARG 170 CD  
546 1 Y 1 R ARG 170 ? NE  ? D ARG 170 NE  
547 1 Y 1 R ARG 170 ? CZ  ? D ARG 170 CZ  
548 1 Y 1 R ARG 170 ? NH1 ? D ARG 170 NH1 
549 1 Y 1 R ARG 170 ? NH2 ? D ARG 170 NH2 
550 1 Y 1 R HIS 175 ? CG  ? D HIS 175 CG  
551 1 Y 1 R HIS 175 ? ND1 ? D HIS 175 ND1 
552 1 Y 1 R HIS 175 ? CD2 ? D HIS 175 CD2 
553 1 Y 1 R HIS 175 ? CE1 ? D HIS 175 CE1 
554 1 Y 1 R HIS 175 ? NE2 ? D HIS 175 NE2 
555 1 Y 1 R GLN 179 ? CG  ? D GLN 179 CG  
556 1 Y 1 R GLN 179 ? CD  ? D GLN 179 CD  
557 1 Y 1 R GLN 179 ? OE1 ? D GLN 179 OE1 
558 1 Y 1 R GLN 179 ? NE2 ? D GLN 179 NE2 
559 1 Y 1 R ARG 183 ? CG  ? D ARG 183 CG  
560 1 Y 1 R ARG 183 ? CD  ? D ARG 183 CD  
561 1 Y 1 R ARG 183 ? NE  ? D ARG 183 NE  
562 1 Y 1 R ARG 183 ? CZ  ? D ARG 183 CZ  
563 1 Y 1 R ARG 183 ? NH1 ? D ARG 183 NH1 
564 1 Y 1 R ARG 183 ? NH2 ? D ARG 183 NH2 
565 1 Y 1 R TYR 188 ? CG  ? D TYR 188 CG  
566 1 Y 1 R TYR 188 ? CD1 ? D TYR 188 CD1 
567 1 Y 1 R TYR 188 ? CD2 ? D TYR 188 CD2 
568 1 Y 1 R TYR 188 ? CE1 ? D TYR 188 CE1 
569 1 Y 1 R TYR 188 ? CE2 ? D TYR 188 CE2 
570 1 Y 1 R TYR 188 ? CZ  ? D TYR 188 CZ  
571 1 Y 1 R TYR 188 ? OH  ? D TYR 188 OH  
572 1 Y 1 R ARG 214 ? CG  ? D ARG 214 CG  
573 1 Y 1 R ARG 214 ? CD  ? D ARG 214 CD  
574 1 Y 1 R ARG 214 ? NE  ? D ARG 214 NE  
575 1 Y 1 R ARG 214 ? CZ  ? D ARG 214 CZ  
576 1 Y 1 R ARG 214 ? NH1 ? D ARG 214 NH1 
577 1 Y 1 R ARG 214 ? NH2 ? D ARG 214 NH2 
578 1 Y 1 R GLN 219 ? CG  ? D GLN 219 CG  
579 1 Y 1 R GLN 219 ? CD  ? D GLN 219 CD  
580 1 Y 1 R GLN 219 ? OE1 ? D GLN 219 OE1 
581 1 Y 1 R GLN 219 ? NE2 ? D GLN 219 NE2 
582 1 Y 1 R LYS 220 ? CG  ? D LYS 220 CG  
583 1 Y 1 R LYS 220 ? CD  ? D LYS 220 CD  
584 1 Y 1 R LYS 220 ? CE  ? D LYS 220 CE  
585 1 Y 1 R LYS 220 ? NZ  ? D LYS 220 NZ  
586 1 Y 1 R ASP 224 ? CG  ? D ASP 224 CG  
587 1 Y 1 R ASP 224 ? OD1 ? D ASP 224 OD1 
588 1 Y 1 R ASP 224 ? OD2 ? D ASP 224 OD2 
589 1 Y 1 R ARG 228 ? CG  ? D ARG 228 CG  
590 1 Y 1 R ARG 228 ? CD  ? D ARG 228 CD  
591 1 Y 1 R ARG 228 ? NE  ? D ARG 228 NE  
592 1 Y 1 R ARG 228 ? CZ  ? D ARG 228 CZ  
593 1 Y 1 R ARG 228 ? NH1 ? D ARG 228 NH1 
594 1 Y 1 R ARG 228 ? NH2 ? D ARG 228 NH2 
595 1 Y 1 R SER 232 ? OG  ? D SER 232 OG  
596 1 Y 1 R LEU 247 ? CG  ? D LEU 247 CG  
597 1 Y 1 R LEU 247 ? CD1 ? D LEU 247 CD1 
598 1 Y 1 R LEU 247 ? CD2 ? D LEU 247 CD2 
599 1 Y 1 R VAL 250 ? CG1 ? D VAL 250 CG1 
600 1 Y 1 R VAL 250 ? CG2 ? D VAL 250 CG2 
601 1 Y 1 R GLU 255 ? CG  ? D GLU 255 CG  
602 1 Y 1 R GLU 255 ? CD  ? D GLU 255 CD  
603 1 Y 1 R GLU 255 ? OE1 ? D GLU 255 OE1 
604 1 Y 1 R GLU 255 ? OE2 ? D GLU 255 OE2 
605 1 Y 1 R ASP 259 ? CG  ? D ASP 259 CG  
606 1 Y 1 R ASP 259 ? OD1 ? D ASP 259 OD1 
607 1 Y 1 R ASP 259 ? OD2 ? D ASP 259 OD2 
608 1 Y 1 R PHE 260 ? CG  ? D PHE 260 CG  
609 1 Y 1 R PHE 260 ? CD1 ? D PHE 260 CD1 
610 1 Y 1 R PHE 260 ? CD2 ? D PHE 260 CD2 
611 1 Y 1 R PHE 260 ? CE1 ? D PHE 260 CE1 
612 1 Y 1 R PHE 260 ? CE2 ? D PHE 260 CE2 
613 1 Y 1 R PHE 260 ? CZ  ? D PHE 260 CZ  
614 1 Y 1 R LYS 262 ? CG  ? D LYS 262 CG  
615 1 Y 1 R LYS 262 ? CD  ? D LYS 262 CD  
616 1 Y 1 R LYS 262 ? CE  ? D LYS 262 CE  
617 1 Y 1 R LYS 262 ? NZ  ? D LYS 262 NZ  
618 1 Y 1 R VAL 264 ? CG1 ? D VAL 264 CG1 
619 1 Y 1 R VAL 264 ? CG2 ? D VAL 264 CG2 
620 1 Y 1 R SER 276 ? OG  ? D SER 276 OG  
621 1 Y 1 R CYS 287 ? SG  ? D CYS 287 SG  
622 1 Y 1 R SER 290 ? OG  ? D SER 290 OG  
623 1 Y 1 R GLU 291 ? CG  ? D GLU 291 CG  
624 1 Y 1 R GLU 291 ? CD  ? D GLU 291 CD  
625 1 Y 1 R GLU 291 ? OE1 ? D GLU 291 OE1 
626 1 Y 1 R GLU 291 ? OE2 ? D GLU 291 OE2 
627 1 Y 1 R THR 293 ? OG1 ? D THR 293 OG1 
628 1 Y 1 R THR 293 ? CG2 ? D THR 293 CG2 
629 1 Y 1 R ARG 295 ? CG  ? D ARG 295 CG  
630 1 Y 1 R ARG 295 ? CD  ? D ARG 295 CD  
631 1 Y 1 R ARG 295 ? NE  ? D ARG 295 NE  
632 1 Y 1 R ARG 295 ? CZ  ? D ARG 295 CZ  
633 1 Y 1 R ARG 295 ? NH1 ? D ARG 295 NH1 
634 1 Y 1 R ARG 295 ? NH2 ? D ARG 295 NH2 
635 1 Y 1 R ASP 296 ? CG  ? D ASP 296 CG  
636 1 Y 1 R ASP 296 ? OD1 ? D ASP 296 OD1 
637 1 Y 1 R ASP 296 ? OD2 ? D ASP 296 OD2 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8Z5H 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_struct.entry_id                     8Z5H 
_struct.title                        'Cryo-EM structure of the hGPR68-Gs complex in pH6.0' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8Z5H 
_struct_keywords.text            'pH6.0, hGPR68, Gs, MEMBRANE PROTEIN' 
_struct_keywords.pdbx_keywords   'MEMBRANE PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 PDB 8Z5H       8Z5H   ? 1 ? 1 
2 UNP GBB1_HUMAN P62873 ? 2 
;SELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLII
WDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSS
GDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAF
ATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVT
DDGMAVATGSWDSFLKIWN
;
2 
3 UNP GBG2_HUMAN P59768 ? 3 MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFCAIL 1 
4 UNP OGR1_HUMAN Q15743 ? 4 
;MGNITADNSSMSCTIDHTIHQTLAPVVYVTVLVVGFPANCLSLYFGYLQIKARNELGVYLCNLTVADLFYICSLPFWLQY
VLQHDNWSHGDLSCQVCGILLYENIYISVGFLCCISVDRYLAVAHPFRFHQFRTLKAAVGVSVVIWAKELLTSIYFLMHE
EVIEDENQHRVCFEHYPIQAWQRAINYYRFLVGFLFPICLLLASYQGILRAVRRSHGTQKSRKDQIQRLVLSTVVIFLAC
FLPYHVLLLVRSVWEASCDFAKGVFNAYHFSLLLTSFNCVADPVLYCFVSETTHRDLARLRGACLAFLTCSRTGRAREA
;
1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8Z5H A 1 ? 362 ? 8Z5H   0 ? 394 ? 0 394 
2 2 8Z5H B 7 ? 345 ? P62873 2 ? 340 ? 2 340 
3 3 8Z5H G 1 ? 71  ? P59768 1 ? 71  ? 1 71  
4 4 8Z5H R 1 ? 319 ? Q15743 1 ? 319 ? 1 319 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
2 8Z5H MET B 1 ? UNP P62873 ? ? 'initiating methionine' -4 1 
2 8Z5H GLY B 2 ? UNP P62873 ? ? 'expression tag'        -3 2 
2 8Z5H SER B 3 ? UNP P62873 ? ? 'expression tag'        -2 3 
2 8Z5H LEU B 4 ? UNP P62873 ? ? 'expression tag'        -1 4 
2 8Z5H LEU B 5 ? UNP P62873 ? ? 'expression tag'        0  5 
2 8Z5H GLN B 6 ? UNP P62873 ? ? 'expression tag'        1  6 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   tetrameric 
_pdbx_struct_assembly.oligomeric_count     4 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 7   ? ARG A 32  ? SER A 6   ARG A 38  1 ? 26 
HELX_P HELX_P2  AA2 GLY A 46  ? ILE A 56  ? GLY A 52  ILE A 62  1 ? 11 
HELX_P HELX_P3  AA3 LYS A 211 ? PHE A 216 ? LYS A 243 PHE A 248 5 ? 6  
HELX_P HELX_P4  AA4 ARG A 233 ? ASN A 246 ? ARG A 265 ASN A 278 1 ? 14 
HELX_P HELX_P5  AA5 LYS A 261 ? LEU A 270 ? LYS A 293 LEU A 302 1 ? 10 
HELX_P HELX_P6  AA6 LYS A 275 ? PHE A 280 ? LYS A 307 PHE A 312 1 ? 6  
HELX_P HELX_P7  AA7 GLU A 282 ? TYR A 286 ? GLU A 314 TYR A 318 5 ? 5  
HELX_P HELX_P8  AA8 ASP A 299 ? ALA A 319 ? ASP A 331 ALA A 351 1 ? 21 
HELX_P HELX_P9  AA9 GLU A 338 ? TYR A 359 ? GLU A 370 TYR A 391 1 ? 22 
HELX_P HELX_P10 AB1 LEU B 9   ? ALA B 31  ? LEU B 4   ALA B 26  1 ? 23 
HELX_P HELX_P11 AB2 THR B 34  ? THR B 39  ? THR B 29  THR B 34  1 ? 6  
HELX_P HELX_P12 AB3 ALA C 12  ? ASN C 24  ? ALA G 12  ASN G 24  1 ? 13 
HELX_P HELX_P13 AB4 LYS C 29  ? HIS C 44  ? LYS G 29  HIS G 44  1 ? 16 
HELX_P HELX_P14 AB5 THR D 18  ? THR D 22  ? THR R 18  THR R 22  5 ? 5  
HELX_P HELX_P15 AB6 LEU D 23  ? ALA D 52  ? LEU R 23  ALA R 52  1 ? 30 
HELX_P HELX_P16 AB7 GLU D 55  ? GLN D 83  ? GLU R 55  GLN R 83  1 ? 29 
HELX_P HELX_P17 AB8 SER D 93  ? GLU D 103 ? SER R 93  GLU R 103 1 ? 11 
HELX_P HELX_P18 AB9 ASN D 104 ? ALA D 124 ? ASN R 104 ALA R 124 1 ? 21 
HELX_P HELX_P19 AC1 THR D 134 ? TYR D 155 ? THR R 134 TYR R 155 1 ? 22 
HELX_P HELX_P20 AC2 GLN D 179 ? LEU D 195 ? GLN R 179 LEU R 195 1 ? 17 
HELX_P HELX_P21 AC3 LEU D 195 ? ARG D 214 ? LEU R 195 ARG R 214 1 ? 20 
HELX_P HELX_P22 AC4 GLN D 219 ? GLU D 255 ? GLN R 219 GLU R 255 1 ? 37 
HELX_P HELX_P23 AC5 SER D 257 ? VAL D 264 ? SER R 257 VAL R 264 1 ? 8  
HELX_P HELX_P24 AC6 VAL D 264 ? THR D 275 ? VAL R 264 THR R 275 1 ? 12 
HELX_P HELX_P25 AC7 PHE D 277 ? PHE D 288 ? PHE R 277 PHE R 288 1 ? 12 
HELX_P HELX_P26 AC8 SER D 290 ? ARG D 295 ? SER R 290 ARG R 295 1 ? 6  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
_struct_conn.id                            disulf1 
_struct_conn.conn_type_id                  disulf 
_struct_conn.pdbx_leaving_atom_flag        ? 
_struct_conn.pdbx_PDB_id                   ? 
_struct_conn.ptnr1_label_asym_id           D 
_struct_conn.ptnr1_label_comp_id           CYS 
_struct_conn.ptnr1_label_seq_id            13 
_struct_conn.ptnr1_label_atom_id           SG 
_struct_conn.pdbx_ptnr1_label_alt_id       ? 
_struct_conn.pdbx_ptnr1_PDB_ins_code       ? 
_struct_conn.pdbx_ptnr1_standard_comp_id   ? 
_struct_conn.ptnr1_symmetry                1_555 
_struct_conn.ptnr2_label_asym_id           D 
_struct_conn.ptnr2_label_comp_id           CYS 
_struct_conn.ptnr2_label_seq_id            258 
_struct_conn.ptnr2_label_atom_id           SG 
_struct_conn.pdbx_ptnr2_label_alt_id       ? 
_struct_conn.pdbx_ptnr2_PDB_ins_code       ? 
_struct_conn.ptnr1_auth_asym_id            R 
_struct_conn.ptnr1_auth_comp_id            CYS 
_struct_conn.ptnr1_auth_seq_id             13 
_struct_conn.ptnr2_auth_asym_id            R 
_struct_conn.ptnr2_auth_comp_id            CYS 
_struct_conn.ptnr2_auth_seq_id             258 
_struct_conn.ptnr2_symmetry                1_555 
_struct_conn.pdbx_ptnr3_label_atom_id      ? 
_struct_conn.pdbx_ptnr3_label_seq_id       ? 
_struct_conn.pdbx_ptnr3_label_comp_id      ? 
_struct_conn.pdbx_ptnr3_label_asym_id      ? 
_struct_conn.pdbx_ptnr3_label_alt_id       ? 
_struct_conn.pdbx_ptnr3_PDB_ins_code       ? 
_struct_conn.details                       ? 
_struct_conn.pdbx_dist_value               2.228 
_struct_conn.pdbx_value_order              ? 
_struct_conn.pdbx_role                     ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
_pdbx_modification_feature.ordinal                            1 
_pdbx_modification_feature.label_comp_id                      CYS 
_pdbx_modification_feature.label_asym_id                      D 
_pdbx_modification_feature.label_seq_id                       13 
_pdbx_modification_feature.label_alt_id                       ? 
_pdbx_modification_feature.modified_residue_label_comp_id     CYS 
_pdbx_modification_feature.modified_residue_label_asym_id     D 
_pdbx_modification_feature.modified_residue_label_seq_id      258 
_pdbx_modification_feature.modified_residue_label_alt_id      ? 
_pdbx_modification_feature.auth_comp_id                       CYS 
_pdbx_modification_feature.auth_asym_id                       R 
_pdbx_modification_feature.auth_seq_id                        13 
_pdbx_modification_feature.PDB_ins_code                       ? 
_pdbx_modification_feature.symmetry                           1_555 
_pdbx_modification_feature.modified_residue_auth_comp_id      CYS 
_pdbx_modification_feature.modified_residue_auth_asym_id      R 
_pdbx_modification_feature.modified_residue_auth_seq_id       258 
_pdbx_modification_feature.modified_residue_PDB_ins_code      ? 
_pdbx_modification_feature.modified_residue_symmetry          1_555 
_pdbx_modification_feature.comp_id_linking_atom               SG 
_pdbx_modification_feature.modified_residue_id_linking_atom   SG 
_pdbx_modification_feature.modified_residue_id                . 
_pdbx_modification_feature.ref_pcm_id                         . 
_pdbx_modification_feature.ref_comp_id                        . 
_pdbx_modification_feature.type                               None 
_pdbx_modification_feature.category                           'Disulfide bridge' 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 6 ? 
AA2 ? 4 ? 
AA3 ? 4 ? 
AA4 ? 4 ? 
AA5 ? 4 ? 
AA6 ? 4 ? 
AA7 ? 4 ? 
AA8 ? 4 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? parallel      
AA1 3 4 ? parallel      
AA1 4 5 ? parallel      
AA1 5 6 ? parallel      
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA6 3 4 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ILE A 185 ? VAL A 192 ? ILE A 217 VAL A 224 
AA1 2 VAL A 195 ? VAL A 202 ? VAL A 227 VAL A 234 
AA1 3 THR A 34  ? LEU A 40  ? THR A 40  LEU A 46  
AA1 4 ALA A 221 ? ASP A 227 ? ALA A 253 ASP A 259 
AA1 5 SER A 254 ? ASN A 260 ? SER A 286 ASN A 292 
AA1 6 CYS A 327 ? PHE A 331 ? CYS A 359 PHE A 363 
AA2 1 THR B 52  ? LEU B 56  ? THR B 47  LEU B 51  
AA2 2 LEU B 341 ? TRP B 344 ? LEU B 336 TRP B 339 
AA2 3 VAL B 332 ? SER B 336 ? VAL B 327 SER B 331 
AA2 4 VAL B 320 ? VAL B 325 ? VAL B 315 VAL B 320 
AA3 1 ILE B 63  ? TRP B 68  ? ILE B 58  TRP B 63  
AA3 2 LEU B 74  ? SER B 79  ? LEU B 69  SER B 74  
AA3 3 LYS B 83  ? ASP B 88  ? LYS B 78  ASP B 83  
AA3 4 ASN B 93  ? PRO B 99  ? ASN B 88  PRO B 94  
AA4 1 VAL B 105 ? TYR B 110 ? VAL B 100 TYR B 105 
AA4 2 TYR B 116 ? GLY B 121 ? TYR B 111 GLY B 116 
AA4 3 CYS B 126 ? ASN B 130 ? CYS B 121 ASN B 125 
AA4 4 ARG B 139 ? LEU B 144 ? ARG B 134 LEU B 139 
AA5 1 CYS B 154 ? PHE B 156 ? CYS B 149 PHE B 151 
AA5 2 GLN B 161 ? SER B 165 ? GLN B 156 SER B 160 
AA5 3 CYS B 171 ? ASP B 175 ? CYS B 166 ASP B 170 
AA5 4 GLN B 181 ? PHE B 185 ? GLN B 176 PHE B 180 
AA6 1 VAL B 192 ? LEU B 197 ? VAL B 187 LEU B 192 
AA6 2 LEU B 203 ? ALA B 208 ? LEU B 198 ALA B 203 
AA6 3 ALA B 213 ? ASP B 217 ? ALA B 208 ASP B 212 
AA6 4 CYS B 223 ? PHE B 227 ? CYS B 218 PHE B 222 
AA7 1 ILE B 234 ? PHE B 239 ? ILE B 229 PHE B 234 
AA7 2 ALA B 245 ? SER B 250 ? ALA B 240 SER B 245 
AA7 3 CYS B 255 ? ASP B 259 ? CYS B 250 ASP B 254 
AA7 4 GLN B 264 ? TYR B 269 ? GLN B 259 TYR B 264 
AA8 1 ILE B 278 ? SER B 282 ? ILE B 273 SER B 277 
AA8 2 LEU B 289 ? TYR B 294 ? LEU B 284 TYR B 289 
AA8 3 CYS B 299 ? ASP B 303 ? CYS B 294 ASP B 298 
AA8 4 ARG B 309 ? LEU B 313 ? ARG B 304 LEU B 308 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N THR A 188 ? N THR A 220 O MET A 199 ? O MET A 231 
AA1 2 3 O HIS A 198 ? O HIS A 230 N LEU A 37  ? N LEU A 43  
AA1 3 4 N LEU A 40  ? N LEU A 46  O ILE A 223 ? O ILE A 255 
AA1 4 5 N PHE A 224 ? N PHE A 256 O PHE A 258 ? O PHE A 290 
AA1 5 6 N LEU A 257 ? N LEU A 289 O TYR A 328 ? O TYR A 360 
AA2 1 2 N LEU B 56  ? N LEU B 51  O LEU B 341 ? O LEU B 336 
AA2 2 3 O TRP B 344 ? O TRP B 339 N VAL B 332 ? N VAL B 327 
AA2 3 4 O GLY B 335 ? O GLY B 330 N SER B 321 ? N SER B 316 
AA3 1 2 N HIS B 67  ? N HIS B 62  O VAL B 76  ? O VAL B 71  
AA3 2 3 N LEU B 75  ? N LEU B 70  O TRP B 87  ? O TRP B 82  
AA3 3 4 N ILE B 86  ? N ILE B 81  O VAL B 95  ? O VAL B 90  
AA4 1 2 N MET B 106 ? N MET B 101 O GLY B 120 ? O GLY B 115 
AA4 2 3 N CYS B 119 ? N CYS B 114 O SER B 127 ? O SER B 122 
AA4 3 4 N ILE B 128 ? N ILE B 123 O SER B 141 ? O SER B 136 
AA5 1 2 N ARG B 155 ? N ARG B 150 O VAL B 163 ? O VAL B 158 
AA5 2 3 N ILE B 162 ? N ILE B 157 O TRP B 174 ? O TRP B 169 
AA5 3 4 N CYS B 171 ? N CYS B 166 O PHE B 185 ? O PHE B 180 
AA6 1 2 N MET B 193 ? N MET B 188 O GLY B 207 ? O GLY B 202 
AA6 2 3 N SER B 206 ? N SER B 201 O LYS B 214 ? O LYS B 209 
AA6 3 4 N ALA B 213 ? N ALA B 208 O PHE B 227 ? O PHE B 222 
AA7 1 2 N ASN B 235 ? N ASN B 230 O GLY B 249 ? O GLY B 244 
AA7 2 3 N PHE B 246 ? N PHE B 241 O PHE B 258 ? O PHE B 253 
AA7 3 4 N LEU B 257 ? N LEU B 252 O LEU B 266 ? O LEU B 261 
AA8 1 2 N SER B 282 ? N SER B 277 O LEU B 291 ? O LEU B 286 
AA8 2 3 N LEU B 290 ? N LEU B 285 O TRP B 302 ? O TRP B 297 
AA8 3 4 N CYS B 299 ? N CYS B 294 O LEU B 313 ? O LEU B 308 
# 
_pdbx_entry_details.entry_id                   8Z5H 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 ARG A 38  ? ? -90.60  47.89   
2  1 GLN A 59  ? ? -94.01  45.15   
3  1 ARG A 265 ? ? -109.99 40.88   
4  1 ALA A 316 ? ? -81.80  46.73   
5  1 ASP A 354 ? ? 57.93   -128.01 
6  1 GLU A 370 ? ? -140.90 -11.13  
7  1 MET B 61  ? ? -170.36 136.66  
8  1 LEU B 152 ? ? -94.81  -60.53  
9  1 ASP B 153 ? ? -128.38 -168.11 
10 1 THR B 165 ? ? -174.39 144.17  
11 1 LEU B 261 ? ? -94.74  -60.34  
12 1 ASP B 291 ? ? -95.67  35.47   
13 1 HIS G 44  ? ? -94.35  48.89   
14 1 HIS R 17  ? ? -150.60 58.31   
15 1 ALA R 52  ? ? -93.81  49.90   
16 1 ASP R 85  ? ? 49.70   26.30   
17 1 SER R 93  ? ? 64.52   -8.65   
18 1 VAL R 96  ? ? -109.94 -61.14  
19 1 CYS R 172 ? ? -93.48  -64.55  
20 1 PHE R 173 ? ? -140.01 39.77   
21 1 PHE R 194 ? ? -141.05 19.68   
22 1 THR R 275 ? ? -69.79  5.93    
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8Z5H 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    8Z5H 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.3 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               134460 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            6.0 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'Cryo-EM structure of the hGPR68-Gs complex in pH6.0' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       '1, 2, 3, 4' 
# 
_em_imaging.entry_id                        8Z5H 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'TFS KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            DIFFRACTION 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             1200 
_em_imaging.nominal_defocus_max             1800 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              8Z5H 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                8Z5H 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A MET 0   ? A MET 1   
2   1 Y 1 A MET 1   ? A MET 2   
3   1 Y 1 A GLY 2   ? A GLY 3   
4   1 Y 1 A CYS 3   ? A CYS 4   
5   1 Y 1 A THR 4   ? A THR 5   
6   1 Y 1 A VAL 91  ? A VAL 59  
7   1 Y 1 A ASN 92  ? A ASN 60  
8   1 Y 1 A GLY 93  ? A GLY 61  
9   1 Y 1 A TYR 94  ? A TYR 62  
10  1 Y 1 A SER 95  ? A SER 63  
11  1 Y 1 A GLU 96  ? A GLU 64  
12  1 Y 1 A GLU 97  ? A GLU 65  
13  1 Y 1 A GLU 98  ? A GLU 66  
14  1 Y 1 A CYS 99  ? A CYS 67  
15  1 Y 1 A LYS 100 ? A LYS 68  
16  1 Y 1 A GLN 101 ? A GLN 69  
17  1 Y 1 A TYR 102 ? A TYR 70  
18  1 Y 1 A LYS 103 ? A LYS 71  
19  1 Y 1 A ALA 104 ? A ALA 72  
20  1 Y 1 A VAL 105 ? A VAL 73  
21  1 Y 1 A VAL 106 ? A VAL 74  
22  1 Y 1 A TYR 107 ? A TYR 75  
23  1 Y 1 A SER 108 ? A SER 76  
24  1 Y 1 A ASN 109 ? A ASN 77  
25  1 Y 1 A THR 110 ? A THR 78  
26  1 Y 1 A ILE 111 ? A ILE 79  
27  1 Y 1 A GLN 112 ? A GLN 80  
28  1 Y 1 A SER 113 ? A SER 81  
29  1 Y 1 A ILE 114 ? A ILE 82  
30  1 Y 1 A ILE 115 ? A ILE 83  
31  1 Y 1 A ALA 116 ? A ALA 84  
32  1 Y 1 A ILE 117 ? A ILE 85  
33  1 Y 1 A ILE 118 ? A ILE 86  
34  1 Y 1 A ARG 119 ? A ARG 87  
35  1 Y 1 A ALA 120 ? A ALA 88  
36  1 Y 1 A MET 121 ? A MET 89  
37  1 Y 1 A GLY 122 ? A GLY 90  
38  1 Y 1 A ARG 123 ? A ARG 91  
39  1 Y 1 A LEU 124 ? A LEU 92  
40  1 Y 1 A LYS 125 ? A LYS 93  
41  1 Y 1 A ILE 126 ? A ILE 94  
42  1 Y 1 A ASP 127 ? A ASP 95  
43  1 Y 1 A PHE 128 ? A PHE 96  
44  1 Y 1 A GLY 129 ? A GLY 97  
45  1 Y 1 A ASP 130 ? A ASP 98  
46  1 Y 1 A SER 131 ? A SER 99  
47  1 Y 1 A ALA 132 ? A ALA 100 
48  1 Y 1 A ARG 133 ? A ARG 101 
49  1 Y 1 A ALA 134 ? A ALA 102 
50  1 Y 1 A ASP 135 ? A ASP 103 
51  1 Y 1 A ASP 136 ? A ASP 104 
52  1 Y 1 A ALA 137 ? A ALA 105 
53  1 Y 1 A ARG 138 ? A ARG 106 
54  1 Y 1 A GLN 139 ? A GLN 107 
55  1 Y 1 A LEU 140 ? A LEU 108 
56  1 Y 1 A PHE 141 ? A PHE 109 
57  1 Y 1 A VAL 142 ? A VAL 110 
58  1 Y 1 A LEU 143 ? A LEU 111 
59  1 Y 1 A ALA 144 ? A ALA 112 
60  1 Y 1 A GLY 145 ? A GLY 113 
61  1 Y 1 A ALA 146 ? A ALA 114 
62  1 Y 1 A ALA 147 ? A ALA 115 
63  1 Y 1 A GLU 148 ? A GLU 116 
64  1 Y 1 A GLU 149 ? A GLU 117 
65  1 Y 1 A GLY 150 ? A GLY 118 
66  1 Y 1 A PHE 151 ? A PHE 119 
67  1 Y 1 A MET 152 ? A MET 120 
68  1 Y 1 A THR 153 ? A THR 121 
69  1 Y 1 A ALA 154 ? A ALA 122 
70  1 Y 1 A GLU 155 ? A GLU 123 
71  1 Y 1 A LEU 156 ? A LEU 124 
72  1 Y 1 A ALA 157 ? A ALA 125 
73  1 Y 1 A GLY 158 ? A GLY 126 
74  1 Y 1 A VAL 159 ? A VAL 127 
75  1 Y 1 A ILE 160 ? A ILE 128 
76  1 Y 1 A LYS 161 ? A LYS 129 
77  1 Y 1 A ARG 162 ? A ARG 130 
78  1 Y 1 A LEU 163 ? A LEU 131 
79  1 Y 1 A TRP 164 ? A TRP 132 
80  1 Y 1 A LYS 165 ? A LYS 133 
81  1 Y 1 A ASP 166 ? A ASP 134 
82  1 Y 1 A SER 167 ? A SER 135 
83  1 Y 1 A GLY 168 ? A GLY 136 
84  1 Y 1 A VAL 169 ? A VAL 137 
85  1 Y 1 A GLN 170 ? A GLN 138 
86  1 Y 1 A ALA 171 ? A ALA 139 
87  1 Y 1 A CYS 172 ? A CYS 140 
88  1 Y 1 A PHE 173 ? A PHE 141 
89  1 Y 1 A ASN 174 ? A ASN 142 
90  1 Y 1 A ARG 175 ? A ARG 143 
91  1 Y 1 A SER 176 ? A SER 144 
92  1 Y 1 A ARG 177 ? A ARG 145 
93  1 Y 1 A GLU 178 ? A GLU 146 
94  1 Y 1 A TYR 179 ? A TYR 147 
95  1 Y 1 A GLN 180 ? A GLN 148 
96  1 Y 1 A LEU 181 ? A LEU 149 
97  1 Y 1 A ASN 182 ? A ASN 150 
98  1 Y 1 A ASP 183 ? A ASP 151 
99  1 Y 1 A SER 184 ? A SER 152 
100 1 Y 1 A ALA 185 ? A ALA 153 
101 1 Y 1 A ALA 186 ? A ALA 154 
102 1 Y 1 A TYR 187 ? A TYR 155 
103 1 Y 1 A TYR 188 ? A TYR 156 
104 1 Y 1 A LEU 189 ? A LEU 157 
105 1 Y 1 A ASN 190 ? A ASN 158 
106 1 Y 1 A ASP 191 ? A ASP 159 
107 1 Y 1 A LEU 192 ? A LEU 160 
108 1 Y 1 A ASP 193 ? A ASP 161 
109 1 Y 1 A ARG 194 ? A ARG 162 
110 1 Y 1 A ILE 195 ? A ILE 163 
111 1 Y 1 A ALA 196 ? A ALA 164 
112 1 Y 1 A GLN 197 ? A GLN 165 
113 1 Y 1 A PRO 198 ? A PRO 166 
114 1 Y 1 A ASN 199 ? A ASN 167 
115 1 Y 1 A TYR 200 ? A TYR 168 
116 1 Y 1 A ILE 201 ? A ILE 169 
117 1 Y 1 A PRO 202 ? A PRO 170 
118 1 Y 1 A THR 203 ? A THR 171 
119 1 Y 1 A GLN 204 ? A GLN 172 
120 1 Y 1 A GLN 205 ? A GLN 173 
121 1 Y 1 A ASP 206 ? A ASP 174 
122 1 Y 1 A VAL 207 ? A VAL 175 
123 1 Y 1 A LEU 208 ? A LEU 176 
124 1 Y 1 A ARG 209 ? A ARG 177 
125 1 Y 1 A THR 210 ? A THR 178 
126 1 Y 1 A ARG 211 ? A ARG 179 
127 1 Y 1 B MET -4  ? B MET 1   
128 1 Y 1 B GLY -3  ? B GLY 2   
129 1 Y 1 B SER -2  ? B SER 3   
130 1 Y 1 B LEU -1  ? B LEU 4   
131 1 Y 1 B LEU 0   ? B LEU 5   
132 1 Y 1 B GLN 1   ? B GLN 6   
133 1 Y 1 B SER 2   ? B SER 7   
134 1 Y 1 G MET 1   ? C MET 1   
135 1 Y 1 G ALA 2   ? C ALA 2   
136 1 Y 1 G SER 3   ? C SER 3   
137 1 Y 1 G ASN 4   ? C ASN 4   
138 1 Y 1 G ASN 5   ? C ASN 5   
139 1 Y 1 G THR 6   ? C THR 6   
140 1 Y 1 G ALA 7   ? C ALA 7   
141 1 Y 1 G SER 8   ? C SER 8   
142 1 Y 1 G ILE 9   ? C ILE 9   
143 1 Y 1 G ALA 10  ? C ALA 10  
144 1 Y 1 G ARG 62  ? C ARG 62  
145 1 Y 1 G GLU 63  ? C GLU 63  
146 1 Y 1 G LYS 64  ? C LYS 64  
147 1 Y 1 G LYS 65  ? C LYS 65  
148 1 Y 1 G PHE 66  ? C PHE 66  
149 1 Y 1 G PHE 67  ? C PHE 67  
150 1 Y 1 G CYS 68  ? C CYS 68  
151 1 Y 1 G ALA 69  ? C ALA 69  
152 1 Y 1 G ILE 70  ? C ILE 70  
153 1 Y 1 G LEU 71  ? C LEU 71  
154 1 Y 1 R MET 1   ? D MET 1   
155 1 Y 1 R GLY 2   ? D GLY 2   
156 1 Y 1 R ASN 3   ? D ASN 3   
157 1 Y 1 R ILE 4   ? D ILE 4   
158 1 Y 1 R THR 5   ? D THR 5   
159 1 Y 1 R ALA 6   ? D ALA 6   
160 1 Y 1 R ASP 7   ? D ASP 7   
161 1 Y 1 R ASN 8   ? D ASN 8   
162 1 Y 1 R SER 9   ? D SER 9   
163 1 Y 1 R SER 10  ? D SER 10  
164 1 Y 1 R MET 11  ? D MET 11  
165 1 Y 1 R ALA 298 ? D ALA 298 
166 1 Y 1 R ARG 299 ? D ARG 299 
167 1 Y 1 R LEU 300 ? D LEU 300 
168 1 Y 1 R ARG 301 ? D ARG 301 
169 1 Y 1 R GLY 302 ? D GLY 302 
170 1 Y 1 R ALA 303 ? D ALA 303 
171 1 Y 1 R CYS 304 ? D CYS 304 
172 1 Y 1 R LEU 305 ? D LEU 305 
173 1 Y 1 R ALA 306 ? D ALA 306 
174 1 Y 1 R PHE 307 ? D PHE 307 
175 1 Y 1 R LEU 308 ? D LEU 308 
176 1 Y 1 R THR 309 ? D THR 309 
177 1 Y 1 R CYS 310 ? D CYS 310 
178 1 Y 1 R SER 311 ? D SER 311 
179 1 Y 1 R ARG 312 ? D ARG 312 
180 1 Y 1 R THR 313 ? D THR 313 
181 1 Y 1 R GLY 314 ? D GLY 314 
182 1 Y 1 R ARG 315 ? D ARG 315 
183 1 Y 1 R ALA 316 ? D ALA 316 
184 1 Y 1 R ARG 317 ? D ARG 317 
185 1 Y 1 R GLU 318 ? D GLU 318 
186 1 Y 1 R ALA 319 ? D ALA 319 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
PHE N    N N N 247 
PHE CA   C N S 248 
PHE C    C N N 249 
PHE O    O N N 250 
PHE CB   C N N 251 
PHE CG   C Y N 252 
PHE CD1  C Y N 253 
PHE CD2  C Y N 254 
PHE CE1  C Y N 255 
PHE CE2  C Y N 256 
PHE CZ   C Y N 257 
PHE OXT  O N N 258 
PHE H    H N N 259 
PHE H2   H N N 260 
PHE HA   H N N 261 
PHE HB2  H N N 262 
PHE HB3  H N N 263 
PHE HD1  H N N 264 
PHE HD2  H N N 265 
PHE HE1  H N N 266 
PHE HE2  H N N 267 
PHE HZ   H N N 268 
PHE HXT  H N N 269 
PRO N    N N N 270 
PRO CA   C N S 271 
PRO C    C N N 272 
PRO O    O N N 273 
PRO CB   C N N 274 
PRO CG   C N N 275 
PRO CD   C N N 276 
PRO OXT  O N N 277 
PRO H    H N N 278 
PRO HA   H N N 279 
PRO HB2  H N N 280 
PRO HB3  H N N 281 
PRO HG2  H N N 282 
PRO HG3  H N N 283 
PRO HD2  H N N 284 
PRO HD3  H N N 285 
PRO HXT  H N N 286 
SER N    N N N 287 
SER CA   C N S 288 
SER C    C N N 289 
SER O    O N N 290 
SER CB   C N N 291 
SER OG   O N N 292 
SER OXT  O N N 293 
SER H    H N N 294 
SER H2   H N N 295 
SER HA   H N N 296 
SER HB2  H N N 297 
SER HB3  H N N 298 
SER HG   H N N 299 
SER HXT  H N N 300 
THR N    N N N 301 
THR CA   C N S 302 
THR C    C N N 303 
THR O    O N N 304 
THR CB   C N R 305 
THR OG1  O N N 306 
THR CG2  C N N 307 
THR OXT  O N N 308 
THR H    H N N 309 
THR H2   H N N 310 
THR HA   H N N 311 
THR HB   H N N 312 
THR HG1  H N N 313 
THR HG21 H N N 314 
THR HG22 H N N 315 
THR HG23 H N N 316 
THR HXT  H N N 317 
TRP N    N N N 318 
TRP CA   C N S 319 
TRP C    C N N 320 
TRP O    O N N 321 
TRP CB   C N N 322 
TRP CG   C Y N 323 
TRP CD1  C Y N 324 
TRP CD2  C Y N 325 
TRP NE1  N Y N 326 
TRP CE2  C Y N 327 
TRP CE3  C Y N 328 
TRP CZ2  C Y N 329 
TRP CZ3  C Y N 330 
TRP CH2  C Y N 331 
TRP OXT  O N N 332 
TRP H    H N N 333 
TRP H2   H N N 334 
TRP HA   H N N 335 
TRP HB2  H N N 336 
TRP HB3  H N N 337 
TRP HD1  H N N 338 
TRP HE1  H N N 339 
TRP HE3  H N N 340 
TRP HZ2  H N N 341 
TRP HZ3  H N N 342 
TRP HH2  H N N 343 
TRP HXT  H N N 344 
TYR N    N N N 345 
TYR CA   C N S 346 
TYR C    C N N 347 
TYR O    O N N 348 
TYR CB   C N N 349 
TYR CG   C Y N 350 
TYR CD1  C Y N 351 
TYR CD2  C Y N 352 
TYR CE1  C Y N 353 
TYR CE2  C Y N 354 
TYR CZ   C Y N 355 
TYR OH   O N N 356 
TYR OXT  O N N 357 
TYR H    H N N 358 
TYR H2   H N N 359 
TYR HA   H N N 360 
TYR HB2  H N N 361 
TYR HB3  H N N 362 
TYR HD1  H N N 363 
TYR HD2  H N N 364 
TYR HE1  H N N 365 
TYR HE2  H N N 366 
TYR HH   H N N 367 
TYR HXT  H N N 368 
VAL N    N N N 369 
VAL CA   C N S 370 
VAL C    C N N 371 
VAL O    O N N 372 
VAL CB   C N N 373 
VAL CG1  C N N 374 
VAL CG2  C N N 375 
VAL OXT  O N N 376 
VAL H    H N N 377 
VAL H2   H N N 378 
VAL HA   H N N 379 
VAL HB   H N N 380 
VAL HG11 H N N 381 
VAL HG12 H N N 382 
VAL HG13 H N N 383 
VAL HG21 H N N 384 
VAL HG22 H N N 385 
VAL HG23 H N N 386 
VAL HXT  H N N 387 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SER N   CA   sing N N 275 
SER N   H    sing N N 276 
SER N   H2   sing N N 277 
SER CA  C    sing N N 278 
SER CA  CB   sing N N 279 
SER CA  HA   sing N N 280 
SER C   O    doub N N 281 
SER C   OXT  sing N N 282 
SER CB  OG   sing N N 283 
SER CB  HB2  sing N N 284 
SER CB  HB3  sing N N 285 
SER OG  HG   sing N N 286 
SER OXT HXT  sing N N 287 
THR N   CA   sing N N 288 
THR N   H    sing N N 289 
THR N   H2   sing N N 290 
THR CA  C    sing N N 291 
THR CA  CB   sing N N 292 
THR CA  HA   sing N N 293 
THR C   O    doub N N 294 
THR C   OXT  sing N N 295 
THR CB  OG1  sing N N 296 
THR CB  CG2  sing N N 297 
THR CB  HB   sing N N 298 
THR OG1 HG1  sing N N 299 
THR CG2 HG21 sing N N 300 
THR CG2 HG22 sing N N 301 
THR CG2 HG23 sing N N 302 
THR OXT HXT  sing N N 303 
TRP N   CA   sing N N 304 
TRP N   H    sing N N 305 
TRP N   H2   sing N N 306 
TRP CA  C    sing N N 307 
TRP CA  CB   sing N N 308 
TRP CA  HA   sing N N 309 
TRP C   O    doub N N 310 
TRP C   OXT  sing N N 311 
TRP CB  CG   sing N N 312 
TRP CB  HB2  sing N N 313 
TRP CB  HB3  sing N N 314 
TRP CG  CD1  doub Y N 315 
TRP CG  CD2  sing Y N 316 
TRP CD1 NE1  sing Y N 317 
TRP CD1 HD1  sing N N 318 
TRP CD2 CE2  doub Y N 319 
TRP CD2 CE3  sing Y N 320 
TRP NE1 CE2  sing Y N 321 
TRP NE1 HE1  sing N N 322 
TRP CE2 CZ2  sing Y N 323 
TRP CE3 CZ3  doub Y N 324 
TRP CE3 HE3  sing N N 325 
TRP CZ2 CH2  doub Y N 326 
TRP CZ2 HZ2  sing N N 327 
TRP CZ3 CH2  sing Y N 328 
TRP CZ3 HZ3  sing N N 329 
TRP CH2 HH2  sing N N 330 
TRP OXT HXT  sing N N 331 
TYR N   CA   sing N N 332 
TYR N   H    sing N N 333 
TYR N   H2   sing N N 334 
TYR CA  C    sing N N 335 
TYR CA  CB   sing N N 336 
TYR CA  HA   sing N N 337 
TYR C   O    doub N N 338 
TYR C   OXT  sing N N 339 
TYR CB  CG   sing N N 340 
TYR CB  HB2  sing N N 341 
TYR CB  HB3  sing N N 342 
TYR CG  CD1  doub Y N 343 
TYR CG  CD2  sing Y N 344 
TYR CD1 CE1  sing Y N 345 
TYR CD1 HD1  sing N N 346 
TYR CD2 CE2  doub Y N 347 
TYR CD2 HD2  sing N N 348 
TYR CE1 CZ   doub Y N 349 
TYR CE1 HE1  sing N N 350 
TYR CE2 CZ   sing Y N 351 
TYR CE2 HE2  sing N N 352 
TYR CZ  OH   sing N N 353 
TYR OH  HH   sing N N 354 
TYR OXT HXT  sing N N 355 
VAL N   CA   sing N N 356 
VAL N   H    sing N N 357 
VAL N   H2   sing N N 358 
VAL CA  C    sing N N 359 
VAL CA  CB   sing N N 360 
VAL CA  HA   sing N N 361 
VAL C   O    doub N N 362 
VAL C   OXT  sing N N 363 
VAL CB  CG1  sing N N 364 
VAL CB  CG2  sing N N 365 
VAL CB  HB   sing N N 366 
VAL CG1 HG11 sing N N 367 
VAL CG1 HG12 sing N N 368 
VAL CG1 HG13 sing N N 369 
VAL CG2 HG21 sing N N 370 
VAL CG2 HG22 sing N N 371 
VAL CG2 HG23 sing N N 372 
VAL OXT HXT  sing N N 373 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-04-18 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           8Z5H 
_em_admin.last_update        2025-04-23 
_em_admin.map_release_date   2025-04-23 
_em_admin.title              'Cryo-EM structure of the hGPR68-Gs complex in pH6.0' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     NONE 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          7108 
_em_entity_assembly_recombinant.organism             'Spodoptera frugiperda' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         1.875 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'            ? 1  1 ? ? ? ? 
'IMAGE ACQUISITION'             ? 2  ? ? 1 ? ? 
MASKING                         ? 3  ? ? ? ? ? 
'CTF CORRECTION'                ? 4  1 ? ? ? ? 
'LAYERLINE INDEXING'            ? 5  ? ? ? ? ? 
'DIFFRACTION INDEXING'          ? 6  ? ? ? ? ? 
'MODEL FITTING'                 ? 7  ? ? ? ? ? 
'MODEL REFINEMENT'              ? 8  ? ? ? ? ? 
OTHER                           ? 9  ? ? ? ? ? 
'INITIAL EULER ASSIGNMENT'      ? 10 1 ? ? ? ? 
'FINAL EULER ASSIGNMENT'        ? 11 1 ? ? ? ? 
CLASSIFICATION                  ? 12 1 ? ? ? ? 
RECONSTRUCTION                  ? 13 1 ? ? ? ? 
'VOLUME SELECTION'              ? 14 1 1 1 ? ? 
'SERIES ALIGNMENT'              ? 15 1 1 1 ? ? 
'MOLECULAR REPLACEMENT'         ? 16 1 1 1 ? ? 
'LATTICE DISTORTION CORRECTION' ? 17 1 1 1 ? ? 
'SYMMETRY DETERMINATION'        ? 18 1 1 1 ? ? 
'CRYSTALLOGRAPHY MERGING'       ? 19 1 1 1 ? ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'National Natural Science Foundation of China (NSFC)' 
_pdbx_audit_support.country                China 
_pdbx_audit_support.grant_number           81773704 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    8Z5H 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM 1    N N   . LEU A 1 6   ? 134.750 138.538 117.100 1.00 113.95 ? 5   LEU A N   1 
ATOM 2    C CA  . LEU A 1 6   ? 134.702 137.317 117.896 1.00 114.46 ? 5   LEU A CA  1 
ATOM 3    C C   . LEU A 1 6   ? 135.892 137.234 118.846 1.00 114.86 ? 5   LEU A C   1 
ATOM 4    O O   . LEU A 1 6   ? 137.039 137.130 118.413 1.00 114.63 ? 5   LEU A O   1 
ATOM 5    C CB  . LEU A 1 6   ? 134.669 136.086 116.987 1.00 113.22 ? 5   LEU A CB  1 
ATOM 6    N N   . SER A 1 7   ? 135.609 137.279 120.145 1.00 117.96 ? 6   SER A N   1 
ATOM 7    C CA  . SER A 1 7   ? 136.660 137.209 121.145 1.00 118.10 ? 6   SER A CA  1 
ATOM 8    C C   . SER A 1 7   ? 137.199 135.784 121.254 1.00 119.24 ? 6   SER A C   1 
ATOM 9    O O   . SER A 1 7   ? 136.647 134.831 120.696 1.00 119.26 ? 6   SER A O   1 
ATOM 10   C CB  . SER A 1 7   ? 136.141 137.686 122.500 1.00 117.56 ? 6   SER A CB  1 
ATOM 11   O OG  . SER A 1 7   ? 135.186 136.781 123.027 1.00 116.73 ? 6   SER A OG  1 
ATOM 12   N N   . ALA A 1 8   ? 138.308 135.648 121.986 1.00 121.90 ? 7   ALA A N   1 
ATOM 13   C CA  . ALA A 1 8   ? 138.903 134.332 122.190 1.00 121.98 ? 7   ALA A CA  1 
ATOM 14   C C   . ALA A 1 8   ? 137.972 133.422 122.982 1.00 122.60 ? 7   ALA A C   1 
ATOM 15   O O   . ALA A 1 8   ? 137.900 132.215 122.721 1.00 123.12 ? 7   ALA A O   1 
ATOM 16   C CB  . ALA A 1 8   ? 140.251 134.468 122.897 1.00 120.79 ? 7   ALA A CB  1 
ATOM 17   N N   . GLU A 1 9   ? 137.254 133.985 123.958 1.00 119.24 ? 8   GLU A N   1 
ATOM 18   C CA  . GLU A 1 9   ? 136.317 133.188 124.743 1.00 118.99 ? 8   GLU A CA  1 
ATOM 19   C C   . GLU A 1 9   ? 135.206 132.622 123.867 1.00 118.90 ? 8   GLU A C   1 
ATOM 20   O O   . GLU A 1 9   ? 134.815 131.458 124.022 1.00 118.24 ? 8   GLU A O   1 
ATOM 21   C CB  . GLU A 1 9   ? 135.732 134.032 125.875 1.00 116.66 ? 8   GLU A CB  1 
ATOM 22   N N   . ASP A 1 10  ? 134.684 133.431 122.942 1.00 108.63 ? 9   ASP A N   1 
ATOM 23   C CA  . ASP A 1 10  ? 133.645 132.947 122.039 1.00 107.92 ? 9   ASP A CA  1 
ATOM 24   C C   . ASP A 1 10  ? 134.163 131.822 121.153 1.00 109.03 ? 9   ASP A C   1 
ATOM 25   O O   . ASP A 1 10  ? 133.467 130.822 120.934 1.00 111.05 ? 9   ASP A O   1 
ATOM 26   C CB  . ASP A 1 10  ? 133.113 134.100 121.189 1.00 106.20 ? 9   ASP A CB  1 
ATOM 27   N N   . LYS A 1 11  ? 135.384 131.966 120.632 1.00 104.61 ? 10  LYS A N   1 
ATOM 28   C CA  . LYS A 1 11  ? 135.961 130.917 119.799 1.00 105.53 ? 10  LYS A CA  1 
ATOM 29   C C   . LYS A 1 11  ? 136.154 129.630 120.590 1.00 107.49 ? 10  LYS A C   1 
ATOM 30   O O   . LYS A 1 11  ? 135.869 128.534 120.090 1.00 109.24 ? 10  LYS A O   1 
ATOM 31   C CB  . LYS A 1 11  ? 137.288 131.389 119.206 1.00 103.98 ? 10  LYS A CB  1 
ATOM 32   N N   . ALA A 1 12  ? 136.640 129.742 121.829 1.00 100.70 ? 11  ALA A N   1 
ATOM 33   C CA  . ALA A 1 12  ? 136.811 128.557 122.663 1.00 101.45 ? 11  ALA A CA  1 
ATOM 34   C C   . ALA A 1 12  ? 135.474 127.887 122.949 1.00 101.26 ? 11  ALA A C   1 
ATOM 35   O O   . ALA A 1 12  ? 135.365 126.654 122.911 1.00 103.88 ? 11  ALA A O   1 
ATOM 36   C CB  . ALA A 1 12  ? 137.517 128.929 123.966 1.00 101.66 ? 11  ALA A CB  1 
ATOM 37   N N   . ALA A 1 13  ? 134.443 128.685 123.235 1.00 93.79  ? 12  ALA A N   1 
ATOM 38   C CA  . ALA A 1 13  ? 133.122 128.120 123.486 1.00 96.45  ? 12  ALA A CA  1 
ATOM 39   C C   . ALA A 1 13  ? 132.589 127.399 122.256 1.00 96.21  ? 12  ALA A C   1 
ATOM 40   O O   . ALA A 1 13  ? 132.015 126.308 122.367 1.00 100.56 ? 12  ALA A O   1 
ATOM 41   C CB  . ALA A 1 13  ? 132.157 129.220 123.926 1.00 94.30  ? 12  ALA A CB  1 
ATOM 42   N N   . VAL A 1 14  ? 132.776 127.988 121.074 1.00 81.98  ? 13  VAL A N   1 
ATOM 43   C CA  . VAL A 1 14  ? 132.302 127.349 119.849 1.00 82.92  ? 13  VAL A CA  1 
ATOM 44   C C   . VAL A 1 14  ? 133.048 126.043 119.603 1.00 87.26  ? 13  VAL A C   1 
ATOM 45   O O   . VAL A 1 14  ? 132.450 125.036 119.202 1.00 92.31  ? 13  VAL A O   1 
ATOM 46   C CB  . VAL A 1 14  ? 132.426 128.315 118.657 1.00 85.21  ? 13  VAL A CB  1 
ATOM 47   C CG1 . VAL A 1 14  ? 132.181 127.584 117.349 1.00 88.57  ? 13  VAL A CG1 1 
ATOM 48   C CG2 . VAL A 1 14  ? 131.440 129.455 118.807 1.00 83.35  ? 13  VAL A CG2 1 
ATOM 49   N N   . GLU A 1 15  ? 134.362 126.033 119.838 1.00 84.77  ? 14  GLU A N   1 
ATOM 50   C CA  . GLU A 1 15  ? 135.131 124.806 119.646 1.00 87.78  ? 14  GLU A CA  1 
ATOM 51   C C   . GLU A 1 15  ? 134.673 123.710 120.602 1.00 88.73  ? 14  GLU A C   1 
ATOM 52   O O   . GLU A 1 15  ? 134.539 122.541 120.209 1.00 91.25  ? 14  GLU A O   1 
ATOM 53   C CB  . GLU A 1 15  ? 136.622 125.087 119.826 1.00 88.12  ? 14  GLU A CB  1 
ATOM 54   N N   . ARG A 1 16  ? 134.428 124.070 121.864 1.00 84.70  ? 15  ARG A N   1 
ATOM 55   C CA  . ARG A 1 16  ? 133.933 123.093 122.826 1.00 83.44  ? 15  ARG A CA  1 
ATOM 56   C C   . ARG A 1 16  ? 132.569 122.557 122.410 1.00 84.41  ? 15  ARG A C   1 
ATOM 57   O O   . ARG A 1 16  ? 132.300 121.353 122.526 1.00 90.24  ? 15  ARG A O   1 
ATOM 58   C CB  . ARG A 1 16  ? 133.868 123.722 124.216 1.00 82.52  ? 15  ARG A CB  1 
ATOM 59   C CG  . ARG A 1 16  ? 133.924 122.727 125.355 1.00 85.59  ? 15  ARG A CG  1 
ATOM 60   C CD  . ARG A 1 16  ? 133.943 123.441 126.692 1.00 86.94  ? 15  ARG A CD  1 
ATOM 61   N NE  . ARG A 1 16  ? 133.107 124.635 126.683 1.00 89.17  ? 15  ARG A NE  1 
ATOM 62   C CZ  . ARG A 1 16  ? 133.009 125.488 127.694 1.00 89.65  ? 15  ARG A CZ  1 
ATOM 63   N NH1 . ARG A 1 16  ? 133.685 125.310 128.817 1.00 88.67  ? 15  ARG A NH1 1 
ATOM 64   N NH2 . ARG A 1 16  ? 132.213 126.547 127.574 1.00 87.70  ? 15  ARG A NH2 1 
ATOM 65   N N   . SER A 1 17  ? 131.698 123.439 121.914 1.00 72.08  ? 16  SER A N   1 
ATOM 66   C CA  . SER A 1 17  ? 130.389 123.000 121.447 1.00 72.46  ? 16  SER A CA  1 
ATOM 67   C C   . SER A 1 17  ? 130.516 122.034 120.278 1.00 76.16  ? 16  SER A C   1 
ATOM 68   O O   . SER A 1 17  ? 129.785 121.040 120.204 1.00 80.09  ? 16  SER A O   1 
ATOM 69   C CB  . SER A 1 17  ? 129.540 124.207 121.056 1.00 73.75  ? 16  SER A CB  1 
ATOM 70   O OG  . SER A 1 17  ? 128.279 123.799 120.560 1.00 74.36  ? 16  SER A OG  1 
ATOM 71   N N   . LYS A 1 18  ? 131.437 122.308 119.352 1.00 78.08  ? 17  LYS A N   1 
ATOM 72   C CA  . LYS A 1 18  ? 131.633 121.404 118.221 1.00 78.78  ? 17  LYS A CA  1 
ATOM 73   C C   . LYS A 1 18  ? 132.143 120.041 118.676 1.00 78.80  ? 17  LYS A C   1 
ATOM 74   O O   . LYS A 1 18  ? 131.699 119.006 118.164 1.00 81.92  ? 17  LYS A O   1 
ATOM 75   C CB  . LYS A 1 18  ? 132.590 122.023 117.202 1.00 78.91  ? 17  LYS A CB  1 
ATOM 76   C CG  . LYS A 1 18  ? 132.098 123.324 116.593 1.00 79.26  ? 17  LYS A CG  1 
ATOM 77   C CD  . LYS A 1 18  ? 130.803 123.121 115.827 1.00 80.53  ? 17  LYS A CD  1 
ATOM 78   C CE  . LYS A 1 18  ? 131.018 122.258 114.596 1.00 81.68  ? 17  LYS A CE  1 
ATOM 79   N NZ  . LYS A 1 18  ? 131.908 122.920 113.604 1.00 81.85  ? 17  LYS A NZ  1 
ATOM 80   N N   . MET A 1 19  ? 133.076 120.017 119.631 1.00 67.16  ? 18  MET A N   1 
ATOM 81   C CA  . MET A 1 19  ? 133.562 118.735 120.140 1.00 64.50  ? 18  MET A CA  1 
ATOM 82   C C   . MET A 1 19  ? 132.440 117.941 120.805 1.00 67.35  ? 18  MET A C   1 
ATOM 83   O O   . MET A 1 19  ? 132.298 116.728 120.579 1.00 69.99  ? 18  MET A O   1 
ATOM 84   C CB  . MET A 1 19  ? 134.713 118.960 121.118 1.00 61.27  ? 18  MET A CB  1 
ATOM 85   N N   . ILE A 1 20  ? 131.620 118.614 121.615 1.00 63.18  ? 26  ILE A N   1 
ATOM 86   C CA  . ILE A 1 20  ? 130.505 117.938 122.270 1.00 60.45  ? 26  ILE A CA  1 
ATOM 87   C C   . ILE A 1 20  ? 129.512 117.417 121.237 1.00 64.96  ? 26  ILE A C   1 
ATOM 88   O O   . ILE A 1 20  ? 128.981 116.307 121.371 1.00 72.16  ? 26  ILE A O   1 
ATOM 89   C CB  . ILE A 1 20  ? 129.835 118.882 123.283 1.00 61.20  ? 26  ILE A CB  1 
ATOM 90   C CG1 . ILE A 1 20  ? 130.743 119.086 124.493 1.00 64.27  ? 26  ILE A CG1 1 
ATOM 91   C CG2 . ILE A 1 20  ? 128.495 118.332 123.729 1.00 64.46  ? 26  ILE A CG2 1 
ATOM 92   C CD1 . ILE A 1 20  ? 130.185 120.042 125.517 1.00 66.26  ? 26  ILE A CD1 1 
ATOM 93   N N   . GLU A 1 21  ? 129.246 118.203 120.192 1.00 60.87  ? 27  GLU A N   1 
ATOM 94   C CA  . GLU A 1 21  ? 128.322 117.764 119.151 1.00 60.89  ? 27  GLU A CA  1 
ATOM 95   C C   . GLU A 1 21  ? 128.859 116.545 118.413 1.00 64.00  ? 27  GLU A C   1 
ATOM 96   O O   . GLU A 1 21  ? 128.097 115.633 118.072 1.00 69.15  ? 27  GLU A O   1 
ATOM 97   C CB  . GLU A 1 21  ? 128.050 118.906 118.175 1.00 58.74  ? 27  GLU A CB  1 
ATOM 98   N N   . LYS A 1 22  ? 130.166 116.515 118.149 1.00 60.47  ? 28  LYS A N   1 
ATOM 99   C CA  . LYS A 1 22  ? 130.758 115.347 117.503 1.00 59.21  ? 28  LYS A CA  1 
ATOM 100  C C   . LYS A 1 22  ? 130.600 114.105 118.372 1.00 64.44  ? 28  LYS A C   1 
ATOM 101  O O   . LYS A 1 22  ? 130.242 113.026 117.879 1.00 69.04  ? 28  LYS A O   1 
ATOM 102  C CB  . LYS A 1 22  ? 132.232 115.608 117.199 1.00 57.40  ? 28  LYS A CB  1 
ATOM 103  N N   . GLN A 1 23  ? 130.848 114.242 119.677 1.00 65.32  ? 29  GLN A N   1 
ATOM 104  C CA  . GLN A 1 23  ? 130.676 113.096 120.568 1.00 59.52  ? 29  GLN A CA  1 
ATOM 105  C C   . GLN A 1 23  ? 129.223 112.630 120.606 1.00 59.88  ? 29  GLN A C   1 
ATOM 106  O O   . GLN A 1 23  ? 128.948 111.423 120.621 1.00 65.96  ? 29  GLN A O   1 
ATOM 107  C CB  . GLN A 1 23  ? 131.165 113.438 121.971 1.00 59.55  ? 29  GLN A CB  1 
ATOM 108  C CG  . GLN A 1 23  ? 131.089 112.277 122.939 1.00 65.04  ? 29  GLN A CG  1 
ATOM 109  C CD  . GLN A 1 23  ? 132.291 111.364 122.840 1.00 71.24  ? 29  GLN A CD  1 
ATOM 110  O OE1 . GLN A 1 23  ? 133.195 111.594 122.039 1.00 71.45  ? 29  GLN A OE1 1 
ATOM 111  N NE2 . GLN A 1 23  ? 132.308 110.319 123.657 1.00 68.23  ? 29  GLN A NE2 1 
ATOM 112  N N   . LEU A 1 24  ? 128.278 113.571 120.629 1.00 58.44  ? 30  LEU A N   1 
ATOM 113  C CA  . LEU A 1 24  ? 126.866 113.201 120.652 1.00 60.04  ? 30  LEU A CA  1 
ATOM 114  C C   . LEU A 1 24  ? 126.458 112.495 119.365 1.00 60.71  ? 30  LEU A C   1 
ATOM 115  O O   . LEU A 1 24  ? 125.668 111.543 119.390 1.00 62.45  ? 30  LEU A O   1 
ATOM 116  C CB  . LEU A 1 24  ? 126.006 114.441 120.887 1.00 60.24  ? 30  LEU A CB  1 
ATOM 117  C CG  . LEU A 1 24  ? 125.513 114.670 122.317 1.00 59.49  ? 30  LEU A CG  1 
ATOM 118  C CD1 . LEU A 1 24  ? 126.665 114.625 123.301 1.00 61.71  ? 30  LEU A CD1 1 
ATOM 119  C CD2 . LEU A 1 24  ? 124.794 115.996 122.412 1.00 62.09  ? 30  LEU A CD2 1 
ATOM 120  N N   . GLN A 1 25  ? 126.976 112.957 118.225 1.00 63.70  ? 31  GLN A N   1 
ATOM 121  C CA  . GLN A 1 25  ? 126.709 112.274 116.964 1.00 62.01  ? 31  GLN A CA  1 
ATOM 122  C C   . GLN A 1 25  ? 127.286 110.866 116.973 1.00 59.72  ? 31  GLN A C   1 
ATOM 123  O O   . GLN A 1 25  ? 126.692 109.941 116.409 1.00 61.15  ? 31  GLN A O   1 
ATOM 124  C CB  . GLN A 1 25  ? 127.275 113.080 115.797 1.00 59.11  ? 31  GLN A CB  1 
ATOM 125  N N   . LYS A 1 26  ? 128.451 110.687 117.598 1.00 56.32  ? 32  LYS A N   1 
ATOM 126  C CA  . LYS A 1 26  ? 129.003 109.344 117.746 1.00 54.03  ? 32  LYS A CA  1 
ATOM 127  C C   . LYS A 1 26  ? 128.093 108.463 118.594 1.00 56.78  ? 32  LYS A C   1 
ATOM 128  O O   . LYS A 1 26  ? 127.894 107.283 118.285 1.00 63.86  ? 32  LYS A O   1 
ATOM 129  C CB  . LYS A 1 26  ? 130.401 109.413 118.359 1.00 54.76  ? 32  LYS A CB  1 
ATOM 130  N N   . ASP A 1 27  ? 127.536 109.019 119.671 1.00 57.45  ? 33  ASP A N   1 
ATOM 131  C CA  . ASP A 1 27  ? 126.685 108.232 120.562 1.00 54.87  ? 33  ASP A CA  1 
ATOM 132  C C   . ASP A 1 27  ? 125.318 107.921 119.962 1.00 56.58  ? 33  ASP A C   1 
ATOM 133  O O   . ASP A 1 27  ? 124.697 106.924 120.351 1.00 60.18  ? 33  ASP A O   1 
ATOM 134  C CB  . ASP A 1 27  ? 126.506 108.960 121.894 1.00 54.76  ? 33  ASP A CB  1 
ATOM 135  N N   . LYS A 1 28  ? 124.830 108.754 119.040 1.00 65.75  ? 34  LYS A N   1 
ATOM 136  C CA  . LYS A 1 28  ? 123.510 108.525 118.455 1.00 61.20  ? 34  LYS A CA  1 
ATOM 137  C C   . LYS A 1 28  ? 123.455 107.211 117.686 1.00 65.17  ? 34  LYS A C   1 
ATOM 138  O O   . LYS A 1 28  ? 122.456 106.484 117.754 1.00 68.94  ? 34  LYS A O   1 
ATOM 139  C CB  . LYS A 1 28  ? 123.130 109.689 117.541 1.00 58.55  ? 34  LYS A CB  1 
ATOM 140  N N   . GLN A 1 29  ? 124.510 106.900 116.930 1.00 72.32  ? 35  GLN A N   1 
ATOM 141  C CA  . GLN A 1 29  ? 124.535 105.656 116.168 1.00 70.55  ? 35  GLN A CA  1 
ATOM 142  C C   . GLN A 1 29  ? 124.510 104.438 117.079 1.00 71.99  ? 35  GLN A C   1 
ATOM 143  O O   . GLN A 1 29  ? 123.820 103.457 116.779 1.00 75.62  ? 35  GLN A O   1 
ATOM 144  C CB  . GLN A 1 29  ? 125.768 105.620 115.268 1.00 69.95  ? 35  GLN A CB  1 
ATOM 145  C CG  . GLN A 1 29  ? 125.768 106.681 114.186 1.00 71.15  ? 35  GLN A CG  1 
ATOM 146  C CD  . GLN A 1 29  ? 127.070 106.726 113.418 1.00 77.70  ? 35  GLN A CD  1 
ATOM 147  O OE1 . GLN A 1 29  ? 128.019 106.012 113.740 1.00 81.23  ? 35  GLN A OE1 1 
ATOM 148  N NE2 . GLN A 1 29  ? 127.124 107.570 112.394 1.00 76.64  ? 35  GLN A NE2 1 
ATOM 149  N N   . VAL A 1 30  ? 125.254 104.476 118.184 1.00 60.73  ? 36  VAL A N   1 
ATOM 150  C CA  . VAL A 1 30  ? 125.221 103.375 119.140 1.00 60.06  ? 36  VAL A CA  1 
ATOM 151  C C   . VAL A 1 30  ? 123.840 103.258 119.770 1.00 57.90  ? 36  VAL A C   1 
ATOM 152  O O   . VAL A 1 30  ? 123.321 102.152 119.956 1.00 63.45  ? 36  VAL A O   1 
ATOM 153  C CB  . VAL A 1 30  ? 126.320 103.561 120.202 1.00 64.06  ? 36  VAL A CB  1 
ATOM 154  C CG1 . VAL A 1 30  ? 125.998 102.768 121.455 1.00 62.12  ? 36  VAL A CG1 1 
ATOM 155  C CG2 . VAL A 1 30  ? 127.672 103.149 119.642 1.00 66.45  ? 36  VAL A CG2 1 
ATOM 156  N N   . TYR A 1 31  ? 123.219 104.392 120.103 1.00 57.35  ? 37  TYR A N   1 
ATOM 157  C CA  . TYR A 1 31  ? 121.892 104.349 120.709 1.00 56.13  ? 37  TYR A CA  1 
ATOM 158  C C   . TYR A 1 31  ? 120.868 103.740 119.763 1.00 59.91  ? 37  TYR A C   1 
ATOM 159  O O   . TYR A 1 31  ? 120.028 102.936 120.181 1.00 65.41  ? 37  TYR A O   1 
ATOM 160  C CB  . TYR A 1 31  ? 121.455 105.749 121.134 1.00 60.61  ? 37  TYR A CB  1 
ATOM 161  C CG  . TYR A 1 31  ? 120.030 105.819 121.635 1.00 60.78  ? 37  TYR A CG  1 
ATOM 162  C CD1 . TYR A 1 31  ? 119.713 105.458 122.934 1.00 61.29  ? 37  TYR A CD1 1 
ATOM 163  C CD2 . TYR A 1 31  ? 119.005 106.254 120.810 1.00 62.23  ? 37  TYR A CD2 1 
ATOM 164  C CE1 . TYR A 1 31  ? 118.415 105.523 123.395 1.00 60.15  ? 37  TYR A CE1 1 
ATOM 165  C CE2 . TYR A 1 31  ? 117.704 106.321 121.264 1.00 61.17  ? 37  TYR A CE2 1 
ATOM 166  C CZ  . TYR A 1 31  ? 117.417 105.955 122.557 1.00 61.06  ? 37  TYR A CZ  1 
ATOM 167  O OH  . TYR A 1 31  ? 116.123 106.021 123.013 1.00 66.95  ? 37  TYR A OH  1 
ATOM 168  N N   . ARG A 1 32  ? 120.916 104.108 118.487 1.00 68.84  ? 38  ARG A N   1 
ATOM 169  C CA  . ARG A 1 32  ? 119.965 103.561 117.519 1.00 64.63  ? 38  ARG A CA  1 
ATOM 170  C C   . ARG A 1 32  ? 120.517 102.292 116.873 1.00 67.93  ? 38  ARG A C   1 
ATOM 171  O O   . ARG A 1 32  ? 120.522 102.111 115.658 1.00 75.32  ? 38  ARG A O   1 
ATOM 172  C CB  . ARG A 1 32  ? 119.630 104.625 116.478 1.00 68.97  ? 38  ARG A CB  1 
ATOM 173  C CG  . ARG A 1 32  ? 118.501 104.278 115.520 1.00 72.46  ? 38  ARG A CG  1 
ATOM 174  C CD  . ARG A 1 32  ? 118.447 105.269 114.373 1.00 73.17  ? 38  ARG A CD  1 
ATOM 175  N NE  . ARG A 1 32  ? 119.583 105.119 113.472 1.00 75.40  ? 38  ARG A NE  1 
ATOM 176  C CZ  . ARG A 1 32  ? 119.487 105.026 112.153 1.00 76.17  ? 38  ARG A CZ  1 
ATOM 177  N NH1 . ARG A 1 32  ? 118.316 105.066 111.541 1.00 74.79  ? 38  ARG A NH1 1 
ATOM 178  N NH2 . ARG A 1 32  ? 120.595 104.892 111.430 1.00 75.69  ? 38  ARG A NH2 1 
ATOM 179  N N   . ALA A 1 33  ? 121.019 101.400 117.720 1.00 63.80  ? 39  ALA A N   1 
ATOM 180  C CA  . ALA A 1 33  ? 121.359 100.045 117.319 1.00 61.99  ? 39  ALA A CA  1 
ATOM 181  C C   . ALA A 1 33  ? 121.114 99.041  118.433 1.00 70.77  ? 39  ALA A C   1 
ATOM 182  O O   . ALA A 1 33  ? 121.381 97.852  118.237 1.00 72.23  ? 39  ALA A O   1 
ATOM 183  C CB  . ALA A 1 33  ? 122.822 99.961  116.866 1.00 62.92  ? 39  ALA A CB  1 
ATOM 184  N N   . THR A 1 34  ? 120.620 99.479  119.586 1.00 69.24  ? 40  THR A N   1 
ATOM 185  C CA  . THR A 1 34  ? 120.351 98.621  120.728 1.00 65.01  ? 40  THR A CA  1 
ATOM 186  C C   . THR A 1 34  ? 118.875 98.727  121.066 1.00 67.62  ? 40  THR A C   1 
ATOM 187  O O   . THR A 1 34  ? 118.327 99.832  121.130 1.00 72.59  ? 40  THR A O   1 
ATOM 188  C CB  . THR A 1 34  ? 121.200 99.018  121.938 1.00 65.84  ? 40  THR A CB  1 
ATOM 189  O OG1 . THR A 1 34  ? 120.734 100.268 122.459 1.00 67.14  ? 40  THR A OG1 1 
ATOM 190  C CG2 . THR A 1 34  ? 122.660 99.154  121.546 1.00 66.67  ? 40  THR A CG2 1 
ATOM 191  N N   . HIS A 1 35  ? 118.236 97.586  121.283 1.00 58.02  ? 41  HIS A N   1 
ATOM 192  C CA  . HIS A 1 35  ? 116.803 97.527  121.513 1.00 56.12  ? 41  HIS A CA  1 
ATOM 193  C C   . HIS A 1 35  ? 116.534 97.240  122.982 1.00 60.15  ? 41  HIS A C   1 
ATOM 194  O O   . HIS A 1 35  ? 117.127 96.323  123.559 1.00 70.18  ? 41  HIS A O   1 
ATOM 195  C CB  . HIS A 1 35  ? 116.162 96.465  120.623 1.00 61.09  ? 41  HIS A CB  1 
ATOM 196  C CG  . HIS A 1 35  ? 116.635 96.513  119.205 1.00 61.37  ? 41  HIS A CG  1 
ATOM 197  N ND1 . HIS A 1 35  ? 116.149 97.421  118.290 1.00 61.20  ? 41  HIS A ND1 1 
ATOM 198  C CD2 . HIS A 1 35  ? 117.558 95.775  118.547 1.00 63.75  ? 41  HIS A CD2 1 
ATOM 199  C CE1 . HIS A 1 35  ? 116.749 97.238  117.128 1.00 58.89  ? 41  HIS A CE1 1 
ATOM 200  N NE2 . HIS A 1 35  ? 117.609 96.244  117.257 1.00 64.71  ? 41  HIS A NE2 1 
ATOM 201  N N   . ARG A 1 36  ? 115.647 98.028  123.579 1.00 57.23  ? 42  ARG A N   1 
ATOM 202  C CA  . ARG A 1 36  ? 115.367 97.959  125.005 1.00 57.74  ? 42  ARG A CA  1 
ATOM 203  C C   . ARG A 1 36  ? 114.131 97.107  125.250 1.00 64.68  ? 42  ARG A C   1 
ATOM 204  O O   . ARG A 1 36  ? 113.094 97.307  124.610 1.00 73.25  ? 42  ARG A O   1 
ATOM 205  C CB  . ARG A 1 36  ? 115.172 99.360  125.582 1.00 62.19  ? 42  ARG A CB  1 
ATOM 206  C CG  . ARG A 1 36  ? 116.460 100.145 125.732 1.00 62.98  ? 42  ARG A CG  1 
ATOM 207  C CD  . ARG A 1 36  ? 116.214 101.637 125.626 1.00 62.85  ? 42  ARG A CD  1 
ATOM 208  N NE  . ARG A 1 36  ? 115.824 102.038 124.281 1.00 65.80  ? 42  ARG A NE  1 
ATOM 209  C CZ  . ARG A 1 36  ? 116.644 102.081 123.241 1.00 68.69  ? 42  ARG A CZ  1 
ATOM 210  N NH1 . ARG A 1 36  ? 117.926 101.777 123.357 1.00 68.99  ? 42  ARG A NH1 1 
ATOM 211  N NH2 . ARG A 1 36  ? 116.167 102.443 122.053 1.00 64.22  ? 42  ARG A NH2 1 
ATOM 212  N N   . LEU A 1 37  ? 114.248 96.163  126.176 1.00 49.93  ? 43  LEU A N   1 
ATOM 213  C CA  . LEU A 1 37  ? 113.173 95.250  126.525 1.00 50.17  ? 43  LEU A CA  1 
ATOM 214  C C   . LEU A 1 37  ? 112.884 95.380  128.010 1.00 51.86  ? 43  LEU A C   1 
ATOM 215  O O   . LEU A 1 37  ? 113.799 95.556  128.818 1.00 62.47  ? 43  LEU A O   1 
ATOM 216  C CB  . LEU A 1 37  ? 113.545 93.804  126.198 1.00 53.56  ? 43  LEU A CB  1 
ATOM 217  C CG  . LEU A 1 37  ? 113.916 93.499  124.752 1.00 51.70  ? 43  LEU A CG  1 
ATOM 218  C CD1 . LEU A 1 37  ? 114.867 92.324  124.697 1.00 56.35  ? 43  LEU A CD1 1 
ATOM 219  C CD2 . LEU A 1 37  ? 112.673 93.219  123.936 1.00 54.64  ? 43  LEU A CD2 1 
ATOM 220  N N   . LEU A 1 38  ? 111.610 95.292  128.376 1.00 47.63  ? 44  LEU A N   1 
ATOM 221  C CA  . LEU A 1 38  ? 111.217 95.427  129.774 1.00 47.23  ? 44  LEU A CA  1 
ATOM 222  C C   . LEU A 1 38  ? 110.628 94.113  130.268 1.00 50.62  ? 44  LEU A C   1 
ATOM 223  O O   . LEU A 1 38  ? 109.643 93.626  129.709 1.00 61.54  ? 44  LEU A O   1 
ATOM 224  C CB  . LEU A 1 38  ? 110.228 96.576  129.951 1.00 50.60  ? 44  LEU A CB  1 
ATOM 225  C CG  . LEU A 1 38  ? 109.658 96.796  131.348 1.00 53.72  ? 44  LEU A CG  1 
ATOM 226  C CD1 . LEU A 1 38  ? 110.682 97.452  132.248 1.00 57.36  ? 44  LEU A CD1 1 
ATOM 227  C CD2 . LEU A 1 38  ? 108.408 97.649  131.264 1.00 52.05  ? 44  LEU A CD2 1 
ATOM 228  N N   . LEU A 1 39  ? 111.215 93.557  131.324 1.00 44.37  ? 45  LEU A N   1 
ATOM 229  C CA  . LEU A 1 39  ? 110.833 92.246  131.833 1.00 50.84  ? 45  LEU A CA  1 
ATOM 230  C C   . LEU A 1 39  ? 109.906 92.383  133.036 1.00 55.27  ? 45  LEU A C   1 
ATOM 231  O O   . LEU A 1 39  ? 110.236 93.076  134.003 1.00 65.23  ? 45  LEU A O   1 
ATOM 232  C CB  . LEU A 1 39  ? 112.076 91.448  132.225 1.00 47.60  ? 45  LEU A CB  1 
ATOM 233  C CG  . LEU A 1 39  ? 111.872 90.008  132.688 1.00 47.35  ? 45  LEU A CG  1 
ATOM 234  C CD1 . LEU A 1 39  ? 111.262 89.169  131.584 1.00 54.05  ? 45  LEU A CD1 1 
ATOM 235  C CD2 . LEU A 1 39  ? 113.178 89.408  133.149 1.00 53.29  ? 45  LEU A CD2 1 
ATOM 236  N N   . LEU A 1 40  ? 108.751 91.718  132.977 1.00 48.23  ? 46  LEU A N   1 
ATOM 237  C CA  . LEU A 1 40  ? 107.813 91.687  134.088 1.00 38.58  ? 46  LEU A CA  1 
ATOM 238  C C   . LEU A 1 40  ? 107.387 90.257  134.374 1.00 48.11  ? 46  LEU A C   1 
ATOM 239  O O   . LEU A 1 40  ? 107.357 89.401  133.481 1.00 62.06  ? 46  LEU A O   1 
ATOM 240  C CB  . LEU A 1 40  ? 106.555 92.523  133.831 1.00 47.40  ? 46  LEU A CB  1 
ATOM 241  C CG  . LEU A 1 40  ? 106.625 94.039  133.983 1.00 59.95  ? 46  LEU A CG  1 
ATOM 242  C CD1 . LEU A 1 40  ? 107.386 94.643  132.844 1.00 58.57  ? 46  LEU A CD1 1 
ATOM 243  C CD2 . LEU A 1 40  ? 105.244 94.639  134.076 1.00 58.63  ? 46  LEU A CD2 1 
ATOM 244  N N   . GLY A 1 41  ? 107.048 90.014  135.634 1.00 52.78  ? 47  GLY A N   1 
ATOM 245  C CA  . GLY A 1 41  ? 106.576 88.718  136.065 1.00 53.35  ? 47  GLY A CA  1 
ATOM 246  C C   . GLY A 1 41  ? 106.051 88.737  137.482 1.00 57.29  ? 47  GLY A C   1 
ATOM 247  O O   . GLY A 1 41  ? 105.398 89.698  137.898 1.00 63.51  ? 47  GLY A O   1 
ATOM 248  N N   . ALA A 1 42  ? 106.330 87.678  138.234 1.00 70.31  ? 48  ALA A N   1 
ATOM 249  C CA  . ALA A 1 42  ? 105.900 87.579  139.619 1.00 72.03  ? 48  ALA A CA  1 
ATOM 250  C C   . ALA A 1 42  ? 106.955 86.806  140.395 1.00 73.66  ? 48  ALA A C   1 
ATOM 251  O O   . ALA A 1 42  ? 107.866 86.209  139.818 1.00 77.33  ? 48  ALA A O   1 
ATOM 252  C CB  . ALA A 1 42  ? 104.528 86.909  139.736 1.00 71.69  ? 48  ALA A CB  1 
ATOM 253  N N   . ASP A 1 43  ? 106.824 86.831  141.722 1.00 71.96  ? 49  ASP A N   1 
ATOM 254  C CA  . ASP A 1 43  ? 107.790 86.141  142.570 1.00 73.57  ? 49  ASP A CA  1 
ATOM 255  C C   . ASP A 1 43  ? 107.788 84.642  142.303 1.00 78.40  ? 49  ASP A C   1 
ATOM 256  O O   . ASP A 1 43  ? 108.850 84.011  142.257 1.00 74.91  ? 49  ASP A O   1 
ATOM 257  C CB  . ASP A 1 43  ? 107.492 86.426  144.041 1.00 71.21  ? 49  ASP A CB  1 
ATOM 258  N N   . ASN A 1 44  ? 106.604 84.055  142.120 1.00 77.86  ? 50  ASN A N   1 
ATOM 259  C CA  . ASN A 1 44  ? 106.496 82.628  141.844 1.00 71.20  ? 50  ASN A CA  1 
ATOM 260  C C   . ASN A 1 44  ? 106.934 82.263  140.433 1.00 75.03  ? 50  ASN A C   1 
ATOM 261  O O   . ASN A 1 44  ? 107.055 81.071  140.133 1.00 78.84  ? 50  ASN A O   1 
ATOM 262  C CB  . ASN A 1 44  ? 105.059 82.158  142.070 1.00 69.89  ? 50  ASN A CB  1 
ATOM 263  N N   . SER A 1 45  ? 107.173 83.244  139.569 1.00 72.03  ? 51  SER A N   1 
ATOM 264  C CA  . SER A 1 45  ? 107.572 82.977  138.195 1.00 68.65  ? 51  SER A CA  1 
ATOM 265  C C   . SER A 1 45  ? 109.041 82.564  138.163 1.00 71.81  ? 51  SER A C   1 
ATOM 266  O O   . SER A 1 45  ? 109.672 82.335  139.198 1.00 78.71  ? 51  SER A O   1 
ATOM 267  C CB  . SER A 1 45  ? 107.307 84.198  137.321 1.00 71.23  ? 51  SER A CB  1 
ATOM 268  O OG  . SER A 1 45  ? 105.922 84.490  137.260 1.00 75.62  ? 51  SER A OG  1 
ATOM 269  N N   . GLY A 1 46  ? 109.605 82.463  136.966 1.00 68.44  ? 52  GLY A N   1 
ATOM 270  C CA  . GLY A 1 46  ? 110.992 82.074  136.836 1.00 71.18  ? 52  GLY A CA  1 
ATOM 271  C C   . GLY A 1 46  ? 111.836 83.070  136.071 1.00 75.30  ? 52  GLY A C   1 
ATOM 272  O O   . GLY A 1 46  ? 112.724 82.677  135.309 1.00 81.27  ? 52  GLY A O   1 
ATOM 273  N N   . LYS A 1 47  ? 111.569 84.364  136.257 1.00 70.87  ? 53  LYS A N   1 
ATOM 274  C CA  . LYS A 1 47  ? 112.361 85.377  135.569 1.00 71.91  ? 53  LYS A CA  1 
ATOM 275  C C   . LYS A 1 47  ? 113.799 85.395  136.067 1.00 77.79  ? 53  LYS A C   1 
ATOM 276  O O   . LYS A 1 47  ? 114.720 85.691  135.293 1.00 82.14  ? 53  LYS A O   1 
ATOM 277  C CB  . LYS A 1 47  ? 111.707 86.751  135.724 1.00 72.64  ? 53  LYS A CB  1 
ATOM 278  C CG  . LYS A 1 47  ? 111.793 87.350  137.114 1.00 80.61  ? 53  LYS A CG  1 
ATOM 279  C CD  . LYS A 1 47  ? 111.050 88.674  137.187 1.00 80.00  ? 53  LYS A CD  1 
ATOM 280  C CE  . LYS A 1 47  ? 111.531 89.516  138.358 1.00 78.79  ? 53  LYS A CE  1 
ATOM 281  N NZ  . LYS A 1 47  ? 110.402 90.155  139.084 1.00 75.37  ? 53  LYS A NZ  1 
ATOM 282  N N   . SER A 1 48  ? 114.014 85.066  137.343 1.00 85.75  ? 54  SER A N   1 
ATOM 283  C CA  . SER A 1 48  ? 115.372 84.986  137.868 1.00 87.97  ? 54  SER A CA  1 
ATOM 284  C C   . SER A 1 48  ? 116.166 83.895  137.163 1.00 91.36  ? 54  SER A C   1 
ATOM 285  O O   . SER A 1 48  ? 117.345 84.082  136.845 1.00 95.47  ? 54  SER A O   1 
ATOM 286  C CB  . SER A 1 48  ? 115.340 84.742  139.376 1.00 89.74  ? 54  SER A CB  1 
ATOM 287  O OG  . SER A 1 48  ? 114.794 83.469  139.675 1.00 91.70  ? 54  SER A OG  1 
ATOM 288  N N   . THR A 1 49  ? 115.531 82.752  136.900 1.00 86.80  ? 55  THR A N   1 
ATOM 289  C CA  . THR A 1 49  ? 116.220 81.668  136.208 1.00 84.96  ? 55  THR A CA  1 
ATOM 290  C C   . THR A 1 49  ? 116.640 82.087  134.806 1.00 86.14  ? 55  THR A C   1 
ATOM 291  O O   . THR A 1 49  ? 117.739 81.749  134.353 1.00 87.82  ? 55  THR A O   1 
ATOM 292  C CB  . THR A 1 49  ? 115.329 80.427  136.152 1.00 85.13  ? 55  THR A CB  1 
ATOM 293  N N   . ILE A 1 50  ? 115.777 82.818  134.099 1.00 72.50  ? 56  ILE A N   1 
ATOM 294  C CA  . ILE A 1 50  ? 116.119 83.272  132.755 1.00 70.24  ? 56  ILE A CA  1 
ATOM 295  C C   . ILE A 1 50  ? 117.266 84.273  132.808 1.00 78.62  ? 56  ILE A C   1 
ATOM 296  O O   . ILE A 1 50  ? 118.262 84.143  132.083 1.00 85.86  ? 56  ILE A O   1 
ATOM 297  C CB  . ILE A 1 50  ? 114.884 83.867  132.056 1.00 73.22  ? 56  ILE A CB  1 
ATOM 298  C CG1 . ILE A 1 50  ? 113.835 82.785  131.814 1.00 79.69  ? 56  ILE A CG1 1 
ATOM 299  C CG2 . ILE A 1 50  ? 115.279 84.525  130.751 1.00 69.22  ? 56  ILE A CG2 1 
ATOM 300  C CD1 . ILE A 1 50  ? 112.708 83.225  130.915 1.00 78.27  ? 56  ILE A CD1 1 
ATOM 301  N N   . VAL A 1 51  ? 117.156 85.280  133.681 1.00 85.74  ? 57  VAL A N   1 
ATOM 302  C CA  . VAL A 1 51  ? 118.199 86.301  133.714 1.00 88.37  ? 57  VAL A CA  1 
ATOM 303  C C   . VAL A 1 51  ? 119.510 85.718  134.221 1.00 92.62  ? 57  VAL A C   1 
ATOM 304  O O   . VAL A 1 51  ? 120.583 86.285  133.978 1.00 95.50  ? 57  VAL A O   1 
ATOM 305  C CB  . VAL A 1 51  ? 117.766 87.517  134.554 1.00 87.10  ? 57  VAL A CB  1 
ATOM 306  C CG1 . VAL A 1 51  ? 116.575 88.211  133.913 1.00 88.91  ? 57  VAL A CG1 1 
ATOM 307  C CG2 . VAL A 1 51  ? 117.479 87.118  135.981 1.00 86.81  ? 57  VAL A CG2 1 
ATOM 308  N N   . LYS A 1 52  ? 119.460 84.587  134.928 1.00 95.88  ? 58  LYS A N   1 
ATOM 309  C CA  . LYS A 1 52  ? 120.694 83.935  135.351 1.00 94.30  ? 58  LYS A CA  1 
ATOM 310  C C   . LYS A 1 52  ? 121.282 83.082  134.233 1.00 96.20  ? 58  LYS A C   1 
ATOM 311  O O   . LYS A 1 52  ? 122.378 83.364  133.737 1.00 97.43  ? 58  LYS A O   1 
ATOM 312  C CB  . LYS A 1 52  ? 120.437 83.084  136.598 1.00 91.94  ? 58  LYS A CB  1 
ATOM 313  N N   . GLN A 1 53  ? 120.570 82.039  133.816 1.00 98.78  ? 59  GLN A N   1 
ATOM 314  C CA  . GLN A 1 53  ? 121.100 81.147  132.785 1.00 100.46 ? 59  GLN A CA  1 
ATOM 315  C C   . GLN A 1 53  ? 120.636 81.543  131.386 1.00 98.66  ? 59  GLN A C   1 
ATOM 316  O O   . GLN A 1 53  ? 120.231 80.706  130.580 1.00 95.68  ? 59  GLN A O   1 
ATOM 317  C CB  . GLN A 1 53  ? 120.710 79.707  133.101 1.00 97.79  ? 59  GLN A CB  1 
ATOM 318  N N   . MET A 1 54  ? 120.700 82.838  131.086 1.00 95.33  ? 60  MET A N   1 
ATOM 319  C CA  . MET A 1 54  ? 120.773 83.280  129.698 1.00 95.03  ? 60  MET A CA  1 
ATOM 320  C C   . MET A 1 54  ? 121.909 84.253  129.431 1.00 98.25  ? 60  MET A C   1 
ATOM 321  O O   . MET A 1 54  ? 122.522 84.169  128.361 1.00 102.31 ? 60  MET A O   1 
ATOM 322  C CB  . MET A 1 54  ? 119.448 83.924  129.268 1.00 94.42  ? 60  MET A CB  1 
ATOM 323  C CG  . MET A 1 54  ? 119.576 84.980  128.189 1.00 97.09  ? 60  MET A CG  1 
ATOM 324  S SD  . MET A 1 54  ? 118.077 85.950  128.006 1.00 101.70 ? 60  MET A SD  1 
ATOM 325  C CE  . MET A 1 54  ? 118.257 87.057  129.397 1.00 96.49  ? 60  MET A CE  1 
ATOM 326  N N   . ARG A 1 55  ? 122.243 85.145  130.363 1.00 105.06 ? 61  ARG A N   1 
ATOM 327  C CA  . ARG A 1 55  ? 123.364 86.056  130.187 1.00 109.29 ? 61  ARG A CA  1 
ATOM 328  C C   . ARG A 1 55  ? 124.712 85.392  130.425 1.00 113.50 ? 61  ARG A C   1 
ATOM 329  O O   . ARG A 1 55  ? 125.728 85.891  129.929 1.00 114.15 ? 61  ARG A O   1 
ATOM 330  C CB  . ARG A 1 55  ? 123.222 87.257  131.126 1.00 107.89 ? 61  ARG A CB  1 
ATOM 331  N N   . ILE A 1 56  ? 124.745 84.287  131.173 1.00 121.76 ? 62  ILE A N   1 
ATOM 332  C CA  . ILE A 1 56  ? 125.998 83.567  131.379 1.00 121.24 ? 62  ILE A CA  1 
ATOM 333  C C   . ILE A 1 56  ? 126.471 82.943  130.074 1.00 122.10 ? 62  ILE A C   1 
ATOM 334  O O   . ILE A 1 56  ? 127.672 82.919  129.777 1.00 122.61 ? 62  ILE A O   1 
ATOM 335  C CB  . ILE A 1 56  ? 125.832 82.510  132.486 1.00 118.62 ? 62  ILE A CB  1 
ATOM 336  N N   . TYR A 1 57  ? 125.539 82.430  129.275 1.00 119.40 ? 63  TYR A N   1 
ATOM 337  C CA  . TYR A 1 57  ? 125.856 81.816  127.994 1.00 117.73 ? 63  TYR A CA  1 
ATOM 338  C C   . TYR A 1 57  ? 125.965 82.828  126.862 1.00 116.00 ? 63  TYR A C   1 
ATOM 339  O O   . TYR A 1 57  ? 126.278 82.439  125.732 1.00 116.83 ? 63  TYR A O   1 
ATOM 340  C CB  . TYR A 1 57  ? 124.803 80.762  127.641 1.00 115.30 ? 63  TYR A CB  1 
ATOM 341  N N   . HIS A 1 58  ? 125.717 84.105  127.130 1.00 107.16 ? 64  HIS A N   1 
ATOM 342  C CA  . HIS A 1 58  ? 125.800 85.132  126.100 1.00 108.63 ? 64  HIS A CA  1 
ATOM 343  C C   . HIS A 1 58  ? 126.472 86.389  126.636 1.00 110.49 ? 64  HIS A C   1 
ATOM 344  O O   . HIS A 1 58  ? 125.898 87.476  126.591 1.00 110.15 ? 64  HIS A O   1 
ATOM 345  C CB  . HIS A 1 58  ? 124.408 85.468  125.563 1.00 106.01 ? 64  HIS A CB  1 
ATOM 346  N N   . VAL A 1 180 ? 123.606 99.749  146.602 1.00 109.67 ? 212 VAL A N   1 
ATOM 347  C CA  . VAL A 1 180 ? 123.609 98.473  145.899 1.00 112.26 ? 212 VAL A CA  1 
ATOM 348  C C   . VAL A 1 180 ? 122.603 97.525  146.542 1.00 111.67 ? 212 VAL A C   1 
ATOM 349  O O   . VAL A 1 180 ? 121.938 96.752  145.853 1.00 111.76 ? 212 VAL A O   1 
ATOM 350  C CB  . VAL A 1 180 ? 125.016 97.850  145.879 1.00 112.51 ? 212 VAL A CB  1 
ATOM 351  C CG1 . VAL A 1 180 ? 125.055 96.646  144.949 1.00 109.83 ? 212 VAL A CG1 1 
ATOM 352  C CG2 . VAL A 1 180 ? 126.047 98.887  145.461 1.00 109.54 ? 212 VAL A CG2 1 
ATOM 353  N N   . LYS A 1 181 ? 122.499 97.589  147.871 1.00 101.91 ? 213 LYS A N   1 
ATOM 354  C CA  . LYS A 1 181 ? 121.532 96.754  148.576 1.00 99.70  ? 213 LYS A CA  1 
ATOM 355  C C   . LYS A 1 181 ? 120.106 97.108  148.178 1.00 101.73 ? 213 LYS A C   1 
ATOM 356  O O   . LYS A 1 181 ? 119.264 96.221  148.000 1.00 101.77 ? 213 LYS A O   1 
ATOM 357  C CB  . LYS A 1 181 ? 121.719 96.896  150.087 1.00 98.85  ? 213 LYS A CB  1 
ATOM 358  N N   . THR A 1 182 ? 119.817 98.397  148.037 1.00 100.73 ? 214 THR A N   1 
ATOM 359  C CA  . THR A 1 182 ? 118.510 98.887  147.606 1.00 99.66  ? 214 THR A CA  1 
ATOM 360  C C   . THR A 1 182 ? 118.685 99.497  146.217 1.00 96.31  ? 214 THR A C   1 
ATOM 361  O O   . THR A 1 182 ? 118.937 100.694 146.075 1.00 95.98  ? 214 THR A O   1 
ATOM 362  C CB  . THR A 1 182 ? 117.946 99.900  148.595 1.00 97.41  ? 214 THR A CB  1 
ATOM 363  O OG1 . THR A 1 182 ? 118.921 100.920 148.842 1.00 95.49  ? 214 THR A OG1 1 
ATOM 364  C CG2 . THR A 1 182 ? 117.590 99.219  149.905 1.00 96.17  ? 214 THR A CG2 1 
ATOM 365  N N   . SER A 1 183 ? 118.553 98.661  145.193 1.00 88.24  ? 215 SER A N   1 
ATOM 366  C CA  . SER A 1 183 ? 118.660 99.085  143.807 1.00 85.61  ? 215 SER A CA  1 
ATOM 367  C C   . SER A 1 183 ? 117.342 98.819  143.095 1.00 87.06  ? 215 SER A C   1 
ATOM 368  O O   . SER A 1 183 ? 116.608 97.889  143.442 1.00 92.21  ? 215 SER A O   1 
ATOM 369  C CB  . SER A 1 183 ? 119.800 98.359  143.089 1.00 88.49  ? 215 SER A CB  1 
ATOM 370  O OG  . SER A 1 183 ? 121.001 98.441  143.833 1.00 91.89  ? 215 SER A OG  1 
ATOM 371  N N   . GLY A 1 184 ? 117.043 99.644  142.099 1.00 72.80  ? 216 GLY A N   1 
ATOM 372  C CA  . GLY A 1 184 ? 115.758 99.566  141.438 1.00 76.41  ? 216 GLY A CA  1 
ATOM 373  C C   . GLY A 1 184 ? 115.776 98.896  140.082 1.00 78.70  ? 216 GLY A C   1 
ATOM 374  O O   . GLY A 1 184 ? 114.866 98.129  139.756 1.00 84.02  ? 216 GLY A O   1 
ATOM 375  N N   . ILE A 1 185 ? 116.801 99.171  139.282 1.00 68.68  ? 217 ILE A N   1 
ATOM 376  C CA  . ILE A 1 185 ? 116.885 98.681  137.913 1.00 63.75  ? 217 ILE A CA  1 
ATOM 377  C C   . ILE A 1 185 ? 118.122 97.810  137.777 1.00 67.73  ? 217 ILE A C   1 
ATOM 378  O O   . ILE A 1 185 ? 119.231 98.239  138.117 1.00 72.93  ? 217 ILE A O   1 
ATOM 379  C CB  . ILE A 1 185 ? 116.920 99.837  136.898 1.00 67.50  ? 217 ILE A CB  1 
ATOM 380  C CG1 . ILE A 1 185 ? 115.668 100.701 137.030 1.00 70.32  ? 217 ILE A CG1 1 
ATOM 381  C CG2 . ILE A 1 185 ? 117.041 99.300  135.488 1.00 74.48  ? 217 ILE A CG2 1 
ATOM 382  C CD1 . ILE A 1 185 ? 114.383 99.951  136.760 1.00 68.07  ? 217 ILE A CD1 1 
ATOM 383  N N   . PHE A 1 186 ? 117.932 96.591  137.284 1.00 65.23  ? 218 PHE A N   1 
ATOM 384  C CA  . PHE A 1 186 ? 119.024 95.687  136.960 1.00 62.90  ? 218 PHE A CA  1 
ATOM 385  C C   . PHE A 1 186 ? 119.088 95.528  135.449 1.00 67.44  ? 218 PHE A C   1 
ATOM 386  O O   . PHE A 1 186 ? 118.071 95.237  134.809 1.00 77.60  ? 218 PHE A O   1 
ATOM 387  C CB  . PHE A 1 186 ? 118.834 94.328  137.631 1.00 65.79  ? 218 PHE A CB  1 
ATOM 388  C CG  . PHE A 1 186 ? 119.140 94.331  139.097 1.00 70.45  ? 218 PHE A CG  1 
ATOM 389  C CD1 . PHE A 1 186 ? 120.397 94.683  139.555 1.00 75.14  ? 218 PHE A CD1 1 
ATOM 390  C CD2 . PHE A 1 186 ? 118.172 93.977  140.019 1.00 71.58  ? 218 PHE A CD2 1 
ATOM 391  C CE1 . PHE A 1 186 ? 120.682 94.686  140.907 1.00 74.65  ? 218 PHE A CE1 1 
ATOM 392  C CE2 . PHE A 1 186 ? 118.450 93.977  141.370 1.00 72.99  ? 218 PHE A CE2 1 
ATOM 393  C CZ  . PHE A 1 186 ? 119.708 94.332  141.815 1.00 72.08  ? 218 PHE A CZ  1 
ATOM 394  N N   . GLU A 1 187 ? 120.276 95.720  134.887 1.00 70.02  ? 219 GLU A N   1 
ATOM 395  C CA  . GLU A 1 187 ? 120.481 95.729  133.446 1.00 67.31  ? 219 GLU A CA  1 
ATOM 396  C C   . GLU A 1 187 ? 121.215 94.469  133.014 1.00 71.50  ? 219 GLU A C   1 
ATOM 397  O O   . GLU A 1 187 ? 122.255 94.124  133.583 1.00 75.30  ? 219 GLU A O   1 
ATOM 398  C CB  . GLU A 1 187 ? 121.269 96.967  133.022 1.00 67.99  ? 219 GLU A CB  1 
ATOM 399  C CG  . GLU A 1 187 ? 121.360 97.163  131.527 1.00 74.14  ? 219 GLU A CG  1 
ATOM 400  C CD  . GLU A 1 187 ? 122.113 98.422  131.159 1.00 82.65  ? 219 GLU A CD  1 
ATOM 401  O OE1 . GLU A 1 187 ? 122.717 99.038  132.061 1.00 82.77  ? 219 GLU A OE1 1 
ATOM 402  O OE2 . GLU A 1 187 ? 122.101 98.799  129.971 1.00 82.33  ? 219 GLU A OE2 1 
ATOM 403  N N   . THR A 1 188 ? 120.672 93.789  132.009 1.00 68.63  ? 220 THR A N   1 
ATOM 404  C CA  . THR A 1 188 ? 121.291 92.611  131.418 1.00 64.35  ? 220 THR A CA  1 
ATOM 405  C C   . THR A 1 188 ? 121.549 92.876  129.943 1.00 65.03  ? 220 THR A C   1 
ATOM 406  O O   . THR A 1 188 ? 120.639 93.276  129.215 1.00 72.43  ? 220 THR A O   1 
ATOM 407  C CB  . THR A 1 188 ? 120.402 91.380  131.582 1.00 70.47  ? 220 THR A CB  1 
ATOM 408  O OG1 . THR A 1 188 ? 120.184 91.128  132.974 1.00 74.16  ? 220 THR A OG1 1 
ATOM 409  C CG2 . THR A 1 188 ? 121.055 90.167  130.950 1.00 74.24  ? 220 THR A CG2 1 
ATOM 410  N N   . LYS A 1 189 ? 122.782 92.653  129.504 1.00 61.89  ? 221 LYS A N   1 
ATOM 411  C CA  . LYS A 1 189 ? 123.173 92.881  128.120 1.00 62.00  ? 221 LYS A CA  1 
ATOM 412  C C   . LYS A 1 189 ? 123.440 91.536  127.470 1.00 72.00  ? 221 LYS A C   1 
ATOM 413  O O   . LYS A 1 189 ? 124.234 90.744  127.989 1.00 75.44  ? 221 LYS A O   1 
ATOM 414  C CB  . LYS A 1 189 ? 124.421 93.760  128.034 1.00 64.07  ? 221 LYS A CB  1 
ATOM 415  C CG  . LYS A 1 189 ? 124.236 95.177  128.526 1.00 67.83  ? 221 LYS A CG  1 
ATOM 416  C CD  . LYS A 1 189 ? 125.526 95.968  128.386 1.00 74.58  ? 221 LYS A CD  1 
ATOM 417  C CE  . LYS A 1 189 ? 125.338 97.420  128.791 1.00 75.07  ? 221 LYS A CE  1 
ATOM 418  N NZ  . LYS A 1 189 ? 125.053 97.557  130.246 1.00 73.71  ? 221 LYS A NZ  1 
ATOM 419  N N   . PHE A 1 190 ? 122.786 91.271  126.341 1.00 70.34  ? 222 PHE A N   1 
ATOM 420  C CA  . PHE A 1 190 ? 123.126 90.086  125.567 1.00 62.01  ? 222 PHE A CA  1 
ATOM 421  C C   . PHE A 1 190 ? 123.118 90.435  124.088 1.00 61.73  ? 222 PHE A C   1 
ATOM 422  O O   . PHE A 1 190 ? 122.714 91.527  123.684 1.00 63.72  ? 222 PHE A O   1 
ATOM 423  C CB  . PHE A 1 190 ? 122.211 88.894  125.896 1.00 63.01  ? 222 PHE A CB  1 
ATOM 424  C CG  . PHE A 1 190 ? 120.761 89.114  125.596 1.00 63.66  ? 222 PHE A CG  1 
ATOM 425  C CD1 . PHE A 1 190 ? 119.922 89.669  126.540 1.00 67.65  ? 222 PHE A CD1 1 
ATOM 426  C CD2 . PHE A 1 190 ? 120.223 88.710  124.390 1.00 64.12  ? 222 PHE A CD2 1 
ATOM 427  C CE1 . PHE A 1 190 ? 118.585 89.852  126.271 1.00 72.11  ? 222 PHE A CE1 1 
ATOM 428  C CE2 . PHE A 1 190 ? 118.885 88.890  124.119 1.00 64.19  ? 222 PHE A CE2 1 
ATOM 429  C CZ  . PHE A 1 190 ? 118.068 89.461  125.060 1.00 70.37  ? 222 PHE A CZ  1 
ATOM 430  N N   . GLN A 1 191 ? 123.624 89.509  123.279 1.00 65.44  ? 223 GLN A N   1 
ATOM 431  C CA  . GLN A 1 191 ? 123.913 89.785  121.879 1.00 65.25  ? 223 GLN A CA  1 
ATOM 432  C C   . GLN A 1 191 ? 123.562 88.562  121.048 1.00 71.82  ? 223 GLN A C   1 
ATOM 433  O O   . GLN A 1 191 ? 124.104 87.478  121.279 1.00 77.74  ? 223 GLN A O   1 
ATOM 434  C CB  . GLN A 1 191 ? 125.385 90.161  121.703 1.00 66.93  ? 223 GLN A CB  1 
ATOM 435  C CG  . GLN A 1 191 ? 125.818 90.413  120.278 1.00 72.67  ? 223 GLN A CG  1 
ATOM 436  C CD  . GLN A 1 191 ? 127.265 90.850  120.193 1.00 77.00  ? 223 GLN A CD  1 
ATOM 437  O OE1 . GLN A 1 191 ? 128.137 90.075  119.804 1.00 76.47  ? 223 GLN A OE1 1 
ATOM 438  N NE2 . GLN A 1 191 ? 127.529 92.096  120.562 1.00 73.37  ? 223 GLN A NE2 1 
ATOM 439  N N   . VAL A 1 192 ? 122.659 88.738  120.086 1.00 70.48  ? 224 VAL A N   1 
ATOM 440  C CA  . VAL A 1 192 ? 122.226 87.663  119.199 1.00 62.36  ? 224 VAL A CA  1 
ATOM 441  C C   . VAL A 1 192 ? 122.433 88.118  117.762 1.00 71.47  ? 224 VAL A C   1 
ATOM 442  O O   . VAL A 1 192 ? 121.913 89.167  117.361 1.00 76.47  ? 224 VAL A O   1 
ATOM 443  C CB  . VAL A 1 192 ? 120.758 87.275  119.431 1.00 62.58  ? 224 VAL A CB  1 
ATOM 444  C CG1 . VAL A 1 192 ? 120.377 86.113  118.541 1.00 65.80  ? 224 VAL A CG1 1 
ATOM 445  C CG2 . VAL A 1 192 ? 120.526 86.928  120.887 1.00 68.26  ? 224 VAL A CG2 1 
ATOM 446  N N   . ASP A 1 193 ? 123.152 87.314  116.998 1.00 74.35  ? 225 ASP A N   1 
ATOM 447  C CA  . ASP A 1 193 ? 123.541 87.637  115.637 1.00 72.02  ? 225 ASP A CA  1 
ATOM 448  C C   . ASP A 1 193 ? 124.037 89.030  115.500 1.00 70.50  ? 225 ASP A C   1 
ATOM 449  O O   . ASP A 1 193 ? 123.532 89.758  114.716 1.00 75.93  ? 225 ASP A O   1 
ATOM 450  C CB  . ASP A 1 193 ? 122.442 87.370  114.659 1.00 77.37  ? 225 ASP A CB  1 
ATOM 451  C CG  . ASP A 1 193 ? 122.204 85.926  114.470 1.00 80.57  ? 225 ASP A CG  1 
ATOM 452  O OD1 . ASP A 1 193 ? 122.838 85.139  115.183 1.00 79.57  ? 225 ASP A OD1 1 
ATOM 453  O OD2 . ASP A 1 193 ? 121.385 85.566  113.613 1.00 82.77  ? 225 ASP A OD2 1 
ATOM 454  N N   . LYS A 1 194 ? 124.998 89.378  116.323 1.00 56.19  ? 226 LYS A N   1 
ATOM 455  C CA  . LYS A 1 194 ? 125.653 90.685  116.340 1.00 59.47  ? 226 LYS A CA  1 
ATOM 456  C C   . LYS A 1 194 ? 124.651 91.822  116.520 1.00 66.25  ? 226 LYS A C   1 
ATOM 457  O O   . LYS A 1 194 ? 124.861 92.932  116.026 1.00 70.56  ? 226 LYS A O   1 
ATOM 458  C CB  . LYS A 1 194 ? 126.493 90.906  115.079 1.00 62.80  ? 226 LYS A CB  1 
ATOM 459  N N   . VAL A 1 195 ? 123.557 91.556  117.228 1.00 62.17  ? 227 VAL A N   1 
ATOM 460  C CA  . VAL A 1 195 ? 122.552 92.561  117.552 1.00 54.57  ? 227 VAL A CA  1 
ATOM 461  C C   . VAL A 1 195 ? 122.445 92.643  119.067 1.00 66.51  ? 227 VAL A C   1 
ATOM 462  O O   . VAL A 1 195 ? 122.296 91.614  119.738 1.00 75.33  ? 227 VAL A O   1 
ATOM 463  C CB  . VAL A 1 195 ? 121.189 92.230  116.920 1.00 58.57  ? 227 VAL A CB  1 
ATOM 464  C CG1 . VAL A 1 195 ? 120.184 93.319  117.235 1.00 64.21  ? 227 VAL A CG1 1 
ATOM 465  C CG2 . VAL A 1 195 ? 121.330 92.049  115.420 1.00 65.18  ? 227 VAL A CG2 1 
ATOM 466  N N   . ASN A 1 196 ? 122.522 93.861  119.600 1.00 67.49  ? 228 ASN A N   1 
ATOM 467  C CA  . ASN A 1 196 ? 122.583 94.083  121.038 1.00 66.11  ? 228 ASN A CA  1 
ATOM 468  C C   . ASN A 1 196 ? 121.191 94.252  121.631 1.00 66.56  ? 228 ASN A C   1 
ATOM 469  O O   . ASN A 1 196 ? 120.329 94.911  121.045 1.00 71.31  ? 228 ASN A O   1 
ATOM 470  C CB  . ASN A 1 196 ? 123.425 95.318  121.348 1.00 64.81  ? 228 ASN A CB  1 
ATOM 471  C CG  . ASN A 1 196 ? 124.893 95.104  121.072 1.00 71.37  ? 228 ASN A CG  1 
ATOM 472  O OD1 . ASN A 1 196 ? 125.444 94.045  121.367 1.00 68.13  ? 228 ASN A OD1 1 
ATOM 473  N ND2 . ASN A 1 196 ? 125.539 96.111  120.498 1.00 73.89  ? 228 ASN A ND2 1 
ATOM 474  N N   . PHE A 1 197 ? 120.980 93.658  122.803 1.00 59.56  ? 229 PHE A N   1 
ATOM 475  C CA  . PHE A 1 197 ? 119.730 93.775  123.533 1.00 59.90  ? 229 PHE A CA  1 
ATOM 476  C C   . PHE A 1 197 ? 120.016 94.085  124.994 1.00 62.59  ? 229 PHE A C   1 
ATOM 477  O O   . PHE A 1 197 ? 120.862 93.438  125.627 1.00 69.79  ? 229 PHE A O   1 
ATOM 478  C CB  . PHE A 1 197 ? 118.898 92.492  123.436 1.00 65.94  ? 229 PHE A CB  1 
ATOM 479  C CG  . PHE A 1 197 ? 118.425 92.176  122.049 1.00 63.27  ? 229 PHE A CG  1 
ATOM 480  C CD1 . PHE A 1 197 ? 117.249 92.714  121.567 1.00 62.44  ? 229 PHE A CD1 1 
ATOM 481  C CD2 . PHE A 1 197 ? 119.147 91.328  121.233 1.00 62.01  ? 229 PHE A CD2 1 
ATOM 482  C CE1 . PHE A 1 197 ? 116.811 92.422  120.298 1.00 62.50  ? 229 PHE A CE1 1 
ATOM 483  C CE2 . PHE A 1 197 ? 118.710 91.033  119.964 1.00 61.39  ? 229 PHE A CE2 1 
ATOM 484  C CZ  . PHE A 1 197 ? 117.542 91.581  119.496 1.00 61.46  ? 229 PHE A CZ  1 
ATOM 485  N N   . HIS A 1 198 ? 119.298 95.076  125.519 1.00 55.28  ? 230 HIS A N   1 
ATOM 486  C CA  . HIS A 1 198 ? 119.355 95.467  126.920 1.00 53.81  ? 230 HIS A CA  1 
ATOM 487  C C   . HIS A 1 198 ? 118.017 95.139  127.566 1.00 58.90  ? 230 HIS A C   1 
ATOM 488  O O   . HIS A 1 198 ? 116.974 95.619  127.111 1.00 68.30  ? 230 HIS A O   1 
ATOM 489  C CB  . HIS A 1 198 ? 119.649 96.960  127.064 1.00 57.93  ? 230 HIS A CB  1 
ATOM 490  C CG  . HIS A 1 198 ? 121.008 97.365  126.588 1.00 66.13  ? 230 HIS A CG  1 
ATOM 491  N ND1 . HIS A 1 198 ? 121.278 97.660  125.270 1.00 63.23  ? 230 HIS A ND1 1 
ATOM 492  C CD2 . HIS A 1 198 ? 122.168 97.550  127.259 1.00 70.36  ? 230 HIS A CD2 1 
ATOM 493  C CE1 . HIS A 1 198 ? 122.549 97.995  125.147 1.00 60.83  ? 230 HIS A CE1 1 
ATOM 494  N NE2 . HIS A 1 198 ? 123.113 97.935  126.339 1.00 65.06  ? 230 HIS A NE2 1 
ATOM 495  N N   . MET A 1 199 ? 118.045 94.335  128.622 1.00 60.15  ? 231 MET A N   1 
ATOM 496  C CA  . MET A 1 199 ? 116.859 94.011  129.397 1.00 57.87  ? 231 MET A CA  1 
ATOM 497  C C   . MET A 1 199 ? 116.937 94.689  130.753 1.00 65.97  ? 231 MET A C   1 
ATOM 498  O O   . MET A 1 199 ? 118.016 94.787  131.348 1.00 73.27  ? 231 MET A O   1 
ATOM 499  C CB  . MET A 1 199 ? 116.696 92.506  129.597 1.00 61.26  ? 231 MET A CB  1 
ATOM 500  C CG  . MET A 1 199 ? 116.180 91.758  128.393 1.00 64.81  ? 231 MET A CG  1 
ATOM 501  S SD  . MET A 1 199 ? 115.257 90.300  128.892 1.00 85.29  ? 231 MET A SD  1 
ATOM 502  C CE  . MET A 1 199 ? 116.200 89.779  130.318 1.00 70.57  ? 231 MET A CE  1 
ATOM 503  N N   . PHE A 1 200 ? 115.788 95.141  131.243 1.00 60.88  ? 232 PHE A N   1 
ATOM 504  C CA  . PHE A 1 200 ? 115.703 95.887  132.488 1.00 55.13  ? 232 PHE A CA  1 
ATOM 505  C C   . PHE A 1 200 ? 114.715 95.197  133.414 1.00 57.07  ? 232 PHE A C   1 
ATOM 506  O O   . PHE A 1 200 ? 113.523 95.111  133.102 1.00 65.67  ? 232 PHE A O   1 
ATOM 507  C CB  . PHE A 1 200 ? 115.282 97.328  132.218 1.00 53.21  ? 232 PHE A CB  1 
ATOM 508  C CG  . PHE A 1 200 ? 116.304 98.119  131.465 1.00 58.27  ? 232 PHE A CG  1 
ATOM 509  C CD1 . PHE A 1 200 ? 117.491 98.490  132.066 1.00 64.90  ? 232 PHE A CD1 1 
ATOM 510  C CD2 . PHE A 1 200 ? 116.087 98.482  130.152 1.00 58.40  ? 232 PHE A CD2 1 
ATOM 511  C CE1 . PHE A 1 200 ? 118.436 99.214  131.375 1.00 59.93  ? 232 PHE A CE1 1 
ATOM 512  C CE2 . PHE A 1 200 ? 117.030 99.205  129.456 1.00 62.67  ? 232 PHE A CE2 1 
ATOM 513  C CZ  . PHE A 1 200 ? 118.205 99.571  130.070 1.00 57.34  ? 232 PHE A CZ  1 
ATOM 514  N N   . ASP A 1 201 ? 115.209 94.708  134.545 1.00 57.73  ? 233 ASP A N   1 
ATOM 515  C CA  . ASP A 1 201 ? 114.378 94.097  135.571 1.00 56.58  ? 233 ASP A CA  1 
ATOM 516  C C   . ASP A 1 201 ? 114.191 95.081  136.716 1.00 70.51  ? 233 ASP A C   1 
ATOM 517  O O   . ASP A 1 201 ? 115.133 95.776  137.112 1.00 76.81  ? 233 ASP A O   1 
ATOM 518  C CB  . ASP A 1 201 ? 115.000 92.800  136.090 1.00 59.08  ? 233 ASP A CB  1 
ATOM 519  N N   . VAL A 1 202 ? 112.973 95.135  137.245 1.00 74.60  ? 234 VAL A N   1 
ATOM 520  C CA  . VAL A 1 202 ? 112.585 96.110  138.256 1.00 69.45  ? 234 VAL A CA  1 
ATOM 521  C C   . VAL A 1 202 ? 112.496 95.409  139.603 1.00 72.26  ? 234 VAL A C   1 
ATOM 522  O O   . VAL A 1 202 ? 111.771 94.418  139.749 1.00 77.73  ? 234 VAL A O   1 
ATOM 523  C CB  . VAL A 1 202 ? 111.251 96.783  137.897 1.00 67.78  ? 234 VAL A CB  1 
ATOM 524  C CG1 . VAL A 1 202 ? 110.770 97.638  139.042 1.00 67.48  ? 234 VAL A CG1 1 
ATOM 525  C CG2 . VAL A 1 202 ? 111.407 97.617  136.641 1.00 68.94  ? 234 VAL A CG2 1 
ATOM 526  N N   . GLY A 1 203 ? 113.230 95.927  140.586 1.00 83.97  ? 235 GLY A N   1 
ATOM 527  C CA  . GLY A 1 203 ? 113.220 95.356  141.914 1.00 83.16  ? 235 GLY A CA  1 
ATOM 528  C C   . GLY A 1 203 ? 113.216 96.444  142.970 1.00 88.81  ? 235 GLY A C   1 
ATOM 529  O O   . GLY A 1 203 ? 113.476 97.616  142.690 1.00 91.25  ? 235 GLY A O   1 
ATOM 530  N N   . ALA A 1 204 ? 112.899 96.029  144.195 1.00 98.00  ? 236 ALA A N   1 
ATOM 531  C CA  . ALA A 1 204 ? 112.863 96.879  145.382 1.00 98.09  ? 236 ALA A CA  1 
ATOM 532  C C   . ALA A 1 204 ? 111.828 97.993  145.290 1.00 99.61  ? 236 ALA A C   1 
ATOM 533  O O   . ALA A 1 204 ? 111.917 98.976  146.035 1.00 99.34  ? 236 ALA A O   1 
ATOM 534  C CB  . ALA A 1 204 ? 114.243 97.478  145.688 1.00 94.17  ? 236 ALA A CB  1 
ATOM 535  N N   . GLN A 1 205 ? 110.847 97.872  144.400 1.00 88.49  ? 237 GLN A N   1 
ATOM 536  C CA  . GLN A 1 205 ? 109.812 98.884  144.284 1.00 83.39  ? 237 GLN A CA  1 
ATOM 537  C C   . GLN A 1 205 ? 108.565 98.469  145.061 1.00 90.28  ? 237 GLN A C   1 
ATOM 538  O O   . GLN A 1 205 ? 108.446 97.343  145.551 1.00 90.62  ? 237 GLN A O   1 
ATOM 539  C CB  . GLN A 1 205 ? 109.464 99.131  142.819 1.00 81.14  ? 237 GLN A CB  1 
ATOM 540  C CG  . GLN A 1 205 ? 110.633 99.589  141.981 1.00 83.76  ? 237 GLN A CG  1 
ATOM 541  C CD  . GLN A 1 205 ? 110.899 101.068 142.106 1.00 87.83  ? 237 GLN A CD  1 
ATOM 542  O OE1 . GLN A 1 205 ? 110.248 101.763 142.884 1.00 90.42  ? 237 GLN A OE1 1 
ATOM 543  N NE2 . GLN A 1 205 ? 111.862 101.561 141.341 1.00 87.96  ? 237 GLN A NE2 1 
ATOM 544  N N   . ARG A 1 206 ? 107.620 99.395  145.170 1.00 90.53  ? 238 ARG A N   1 
ATOM 545  C CA  . ARG A 1 206 ? 106.388 99.108  145.893 1.00 86.23  ? 238 ARG A CA  1 
ATOM 546  C C   . ARG A 1 206 ? 105.410 98.346  145.018 1.00 85.55  ? 238 ARG A C   1 
ATOM 547  O O   . ARG A 1 206 ? 105.773 97.857  143.949 1.00 86.05  ? 238 ARG A O   1 
ATOM 548  C CB  . ARG A 1 206 ? 105.748 100.411 146.363 1.00 87.52  ? 238 ARG A CB  1 
ATOM 549  C CG  . ARG A 1 206 ? 106.675 101.300 147.175 1.00 86.81  ? 238 ARG A CG  1 
ATOM 550  C CD  . ARG A 1 206 ? 106.151 102.726 147.261 1.00 88.54  ? 238 ARG A CD  1 
ATOM 551  N NE  . ARG A 1 206 ? 104.794 102.790 147.796 1.00 90.46  ? 238 ARG A NE  1 
ATOM 552  C CZ  . ARG A 1 206 ? 103.696 102.829 147.047 1.00 90.36  ? 238 ARG A CZ  1 
ATOM 553  N NH1 . ARG A 1 206 ? 103.792 102.815 145.725 1.00 88.54  ? 238 ARG A NH1 1 
ATOM 554  N NH2 . ARG A 1 206 ? 102.503 102.886 147.620 1.00 87.76  ? 238 ARG A NH2 1 
ATOM 555  N N   . ASP A 1 207 ? 104.165 98.247  145.467 1.00 84.61  ? 239 ASP A N   1 
ATOM 556  C CA  . ASP A 1 207 ? 103.145 97.548  144.692 1.00 85.98  ? 239 ASP A CA  1 
ATOM 557  C C   . ASP A 1 207 ? 102.588 98.414  143.570 1.00 89.59  ? 239 ASP A C   1 
ATOM 558  O O   . ASP A 1 207 ? 102.204 97.889  142.519 1.00 86.61  ? 239 ASP A O   1 
ATOM 559  C CB  . ASP A 1 207 ? 102.016 97.086  145.612 1.00 83.15  ? 239 ASP A CB  1 
ATOM 560  N N   . GLU A 1 208 ? 102.527 99.728  143.770 1.00 96.82  ? 240 GLU A N   1 
ATOM 561  C CA  . GLU A 1 208 ? 101.962 100.615 142.763 1.00 93.94  ? 240 GLU A CA  1 
ATOM 562  C C   . GLU A 1 208 ? 102.840 100.648 141.519 1.00 93.02  ? 240 GLU A C   1 
ATOM 563  O O   . GLU A 1 208 ? 104.070 100.591 141.602 1.00 96.65  ? 240 GLU A O   1 
ATOM 564  C CB  . GLU A 1 208 ? 101.800 102.025 143.329 1.00 89.95  ? 240 GLU A CB  1 
ATOM 565  N N   . ARG A 1 209 ? 102.195 100.742 140.357 1.00 68.84  ? 241 ARG A N   1 
ATOM 566  C CA  . ARG A 1 209 ? 102.891 100.761 139.082 1.00 68.06  ? 241 ARG A CA  1 
ATOM 567  C C   . ARG A 1 209 ? 102.409 101.870 138.160 1.00 68.24  ? 241 ARG A C   1 
ATOM 568  O O   . ARG A 1 209 ? 102.965 102.031 137.069 1.00 74.20  ? 241 ARG A O   1 
ATOM 569  C CB  . ARG A 1 209 ? 102.736 99.407  138.370 1.00 68.68  ? 241 ARG A CB  1 
ATOM 570  C CG  . ARG A 1 209 ? 103.811 99.101  137.346 1.00 71.86  ? 241 ARG A CG  1 
ATOM 571  C CD  . ARG A 1 209 ? 103.863 97.619  137.029 1.00 74.42  ? 241 ARG A CD  1 
ATOM 572  N NE  . ARG A 1 209 ? 102.537 97.068  136.789 1.00 73.48  ? 241 ARG A NE  1 
ATOM 573  C CZ  . ARG A 1 209 ? 102.211 95.798  136.980 1.00 72.03  ? 241 ARG A CZ  1 
ATOM 574  N NH1 . ARG A 1 209 ? 103.094 94.917  137.418 1.00 69.69  ? 241 ARG A NH1 1 
ATOM 575  N NH2 . ARG A 1 209 ? 100.967 95.403  136.728 1.00 73.29  ? 241 ARG A NH2 1 
ATOM 576  N N   . ARG A 1 210 ? 101.410 102.648 138.570 1.00 68.85  ? 242 ARG A N   1 
ATOM 577  C CA  . ARG A 1 210 ? 100.790 103.620 137.681 1.00 72.30  ? 242 ARG A CA  1 
ATOM 578  C C   . ARG A 1 210 ? 101.718 104.763 137.299 1.00 74.53  ? 242 ARG A C   1 
ATOM 579  O O   . ARG A 1 210 ? 101.380 105.527 136.389 1.00 76.91  ? 242 ARG A O   1 
ATOM 580  C CB  . ARG A 1 210 ? 99.525  104.185 138.329 1.00 72.14  ? 242 ARG A CB  1 
ATOM 581  N N   . LYS A 1 211 ? 102.867 104.904 137.957 1.00 62.69  ? 243 LYS A N   1 
ATOM 582  C CA  . LYS A 1 211 ? 103.728 106.059 137.746 1.00 62.44  ? 243 LYS A CA  1 
ATOM 583  C C   . LYS A 1 211 ? 105.007 105.739 136.989 1.00 66.59  ? 243 LYS A C   1 
ATOM 584  O O   . LYS A 1 211 ? 105.335 106.438 136.027 1.00 70.24  ? 243 LYS A O   1 
ATOM 585  C CB  . LYS A 1 211 ? 104.059 106.710 139.091 1.00 60.42  ? 243 LYS A CB  1 
ATOM 586  C CG  . LYS A 1 211 ? 102.838 107.302 139.754 1.00 62.48  ? 243 LYS A CG  1 
ATOM 587  C CD  . LYS A 1 211 ? 102.472 108.623 139.109 1.00 66.92  ? 243 LYS A CD  1 
ATOM 588  C CE  . LYS A 1 211 ? 100.982 108.884 139.205 1.00 67.55  ? 243 LYS A CE  1 
ATOM 589  N NZ  . LYS A 1 211 ? 100.670 110.336 139.199 1.00 70.86  ? 243 LYS A NZ  1 
ATOM 590  N N   . TRP A 1 212 ? 105.748 104.708 137.386 1.00 57.91  ? 244 TRP A N   1 
ATOM 591  C CA  . TRP A 1 212 ? 106.993 104.414 136.688 1.00 52.49  ? 244 TRP A CA  1 
ATOM 592  C C   . TRP A 1 212 ? 106.789 103.596 135.422 1.00 60.03  ? 244 TRP A C   1 
ATOM 593  O O   . TRP A 1 212 ? 107.756 103.378 134.686 1.00 68.56  ? 244 TRP A O   1 
ATOM 594  C CB  . TRP A 1 212 ? 107.982 103.706 137.619 1.00 55.56  ? 244 TRP A CB  1 
ATOM 595  C CG  . TRP A 1 212 ? 107.566 102.361 138.118 1.00 55.53  ? 244 TRP A CG  1 
ATOM 596  C CD1 . TRP A 1 212 ? 106.978 102.083 139.311 1.00 57.23  ? 244 TRP A CD1 1 
ATOM 597  C CD2 . TRP A 1 212 ? 107.742 101.104 137.455 1.00 56.03  ? 244 TRP A CD2 1 
ATOM 598  N NE1 . TRP A 1 212 ? 106.761 100.734 139.429 1.00 58.59  ? 244 TRP A NE1 1 
ATOM 599  C CE2 . TRP A 1 212 ? 107.222 100.112 138.301 1.00 53.84  ? 244 TRP A CE2 1 
ATOM 600  C CE3 . TRP A 1 212 ? 108.280 100.724 136.223 1.00 62.22  ? 244 TRP A CE3 1 
ATOM 601  C CZ2 . TRP A 1 212 ? 107.222 98.766  137.957 1.00 58.71  ? 244 TRP A CZ2 1 
ATOM 602  C CZ3 . TRP A 1 212 ? 108.278 99.390  135.885 1.00 59.91  ? 244 TRP A CZ3 1 
ATOM 603  C CH2 . TRP A 1 212 ? 107.754 98.427  136.747 1.00 60.55  ? 244 TRP A CH2 1 
ATOM 604  N N   . ILE A 1 213 ? 105.564 103.148 135.142 1.00 65.76  ? 245 ILE A N   1 
ATOM 605  C CA  . ILE A 1 213 ? 105.312 102.405 133.913 1.00 62.84  ? 245 ILE A CA  1 
ATOM 606  C C   . ILE A 1 213 ? 105.334 103.308 132.689 1.00 61.90  ? 245 ILE A C   1 
ATOM 607  O O   . ILE A 1 213 ? 105.535 102.819 131.570 1.00 66.77  ? 245 ILE A O   1 
ATOM 608  C CB  . ILE A 1 213 ? 103.974 101.651 133.999 1.00 62.80  ? 245 ILE A CB  1 
ATOM 609  C CG1 . ILE A 1 213 ? 103.917 100.531 132.960 1.00 64.67  ? 245 ILE A CG1 1 
ATOM 610  C CG2 . ILE A 1 213 ? 102.803 102.606 133.824 1.00 64.78  ? 245 ILE A CG2 1 
ATOM 611  C CD1 . ILE A 1 213 ? 104.895 99.416  133.212 1.00 65.41  ? 245 ILE A CD1 1 
ATOM 612  N N   . GLN A 1 214 ? 105.147 104.614 132.865 1.00 67.63  ? 246 GLN A N   1 
ATOM 613  C CA  . GLN A 1 214 ? 105.096 105.531 131.737 1.00 70.84  ? 246 GLN A CA  1 
ATOM 614  C C   . GLN A 1 214 ? 106.473 105.927 131.231 1.00 68.79  ? 246 GLN A C   1 
ATOM 615  O O   . GLN A 1 214 ? 106.570 106.512 130.148 1.00 72.49  ? 246 GLN A O   1 
ATOM 616  C CB  . GLN A 1 214 ? 104.301 106.780 132.116 1.00 72.50  ? 246 GLN A CB  1 
ATOM 617  C CG  . GLN A 1 214 ? 104.988 107.670 133.122 1.00 75.75  ? 246 GLN A CG  1 
ATOM 618  C CD  . GLN A 1 214 ? 104.129 108.843 133.531 1.00 77.75  ? 246 GLN A CD  1 
ATOM 619  O OE1 . GLN A 1 214 ? 102.948 108.906 133.194 1.00 77.60  ? 246 GLN A OE1 1 
ATOM 620  N NE2 . GLN A 1 214 ? 104.717 109.783 134.260 1.00 79.60  ? 246 GLN A NE2 1 
ATOM 621  N N   . CYS A 1 215 ? 107.534 105.631 131.980 1.00 66.50  ? 247 CYS A N   1 
ATOM 622  C CA  . CYS A 1 215 ? 108.881 105.875 131.488 1.00 66.98  ? 247 CYS A CA  1 
ATOM 623  C C   . CYS A 1 215 ? 109.273 104.922 130.371 1.00 72.73  ? 247 CYS A C   1 
ATOM 624  O O   . CYS A 1 215 ? 110.282 105.162 129.700 1.00 74.89  ? 247 CYS A O   1 
ATOM 625  C CB  . CYS A 1 215 ? 109.889 105.768 132.633 1.00 68.73  ? 247 CYS A CB  1 
ATOM 626  S SG  . CYS A 1 215 ? 109.405 106.626 134.141 1.00 88.87  ? 247 CYS A SG  1 
ATOM 627  N N   . PHE A 1 216 ? 108.506 103.858 130.156 1.00 71.02  ? 248 PHE A N   1 
ATOM 628  C CA  . PHE A 1 216 ? 108.780 102.863 129.125 1.00 64.49  ? 248 PHE A CA  1 
ATOM 629  C C   . PHE A 1 216 ? 107.728 103.025 128.031 1.00 68.67  ? 248 PHE A C   1 
ATOM 630  O O   . PHE A 1 216 ? 106.713 102.332 128.018 1.00 68.08  ? 248 PHE A O   1 
ATOM 631  C CB  . PHE A 1 216 ? 108.759 101.457 129.711 1.00 61.84  ? 248 PHE A CB  1 
ATOM 632  C CG  . PHE A 1 216 ? 109.705 101.264 130.855 1.00 62.20  ? 248 PHE A CG  1 
ATOM 633  C CD1 . PHE A 1 216 ? 111.032 100.954 130.629 1.00 65.95  ? 248 PHE A CD1 1 
ATOM 634  C CD2 . PHE A 1 216 ? 109.266 101.381 132.159 1.00 61.87  ? 248 PHE A CD2 1 
ATOM 635  C CE1 . PHE A 1 216 ? 111.900 100.772 131.680 1.00 67.85  ? 248 PHE A CE1 1 
ATOM 636  C CE2 . PHE A 1 216 ? 110.132 101.202 133.212 1.00 64.64  ? 248 PHE A CE2 1 
ATOM 637  C CZ  . PHE A 1 216 ? 111.449 100.896 132.973 1.00 67.58  ? 248 PHE A CZ  1 
ATOM 638  N N   . ASN A 1 217 ? 107.983 103.944 127.106 1.00 77.07  ? 249 ASN A N   1 
ATOM 639  C CA  . ASN A 1 217 ? 107.095 104.181 125.977 1.00 70.90  ? 249 ASN A CA  1 
ATOM 640  C C   . ASN A 1 217 ? 107.743 103.913 124.632 1.00 77.55  ? 249 ASN A C   1 
ATOM 641  O O   . ASN A 1 217 ? 107.039 103.555 123.687 1.00 83.65  ? 249 ASN A O   1 
ATOM 642  C CB  . ASN A 1 217 ? 106.578 105.627 125.989 1.00 73.43  ? 249 ASN A CB  1 
ATOM 643  C CG  . ASN A 1 217 ? 105.620 105.891 127.127 1.00 81.27  ? 249 ASN A CG  1 
ATOM 644  O OD1 . ASN A 1 217 ? 104.769 105.061 127.441 1.00 83.50  ? 249 ASN A OD1 1 
ATOM 645  N ND2 . ASN A 1 217 ? 105.753 107.053 127.754 1.00 83.46  ? 249 ASN A ND2 1 
ATOM 646  N N   . ASP A 1 218 ? 109.058 104.077 124.519 1.00 71.03  ? 250 ASP A N   1 
ATOM 647  C CA  . ASP A 1 218 ? 109.783 103.794 123.292 1.00 72.43  ? 250 ASP A CA  1 
ATOM 648  C C   . ASP A 1 218 ? 110.461 102.431 123.316 1.00 75.33  ? 250 ASP A C   1 
ATOM 649  O O   . ASP A 1 218 ? 111.260 102.132 122.423 1.00 76.93  ? 250 ASP A O   1 
ATOM 650  C CB  . ASP A 1 218 ? 110.817 104.889 123.027 1.00 68.83  ? 250 ASP A CB  1 
ATOM 651  N N   . VAL A 1 219 ? 110.170 101.602 124.320 1.00 65.07  ? 251 VAL A N   1 
ATOM 652  C CA  . VAL A 1 219 ? 110.785 100.285 124.401 1.00 61.06  ? 251 VAL A CA  1 
ATOM 653  C C   . VAL A 1 219 ? 110.256 99.399  123.282 1.00 64.62  ? 251 VAL A C   1 
ATOM 654  O O   . VAL A 1 219 ? 109.147 99.594  122.767 1.00 65.58  ? 251 VAL A O   1 
ATOM 655  C CB  . VAL A 1 219 ? 110.539 99.650  125.781 1.00 57.72  ? 251 VAL A CB  1 
ATOM 656  C CG1 . VAL A 1 219 ? 110.954 100.607 126.880 1.00 64.18  ? 251 VAL A CG1 1 
ATOM 657  C CG2 . VAL A 1 219 ? 109.084 99.260  125.936 1.00 59.95  ? 251 VAL A CG2 1 
ATOM 658  N N   . THR A 1 220 ? 111.068 98.419  122.886 1.00 60.52  ? 252 THR A N   1 
ATOM 659  C CA  . THR A 1 220 ? 110.681 97.544  121.785 1.00 57.18  ? 252 THR A CA  1 
ATOM 660  C C   . THR A 1 220 ? 109.608 96.549  122.210 1.00 55.92  ? 252 THR A C   1 
ATOM 661  O O   . THR A 1 220 ? 108.639 96.328  121.476 1.00 63.29  ? 252 THR A O   1 
ATOM 662  C CB  . THR A 1 220 ? 111.909 96.818  121.240 1.00 59.89  ? 252 THR A CB  1 
ATOM 663  O OG1 . THR A 1 220 ? 112.763 97.758  120.580 1.00 52.40  ? 252 THR A OG1 1 
ATOM 664  C CG2 . THR A 1 220 ? 111.501 95.744  120.248 1.00 62.32  ? 252 THR A CG2 1 
ATOM 665  N N   . ALA A 1 221 ? 109.747 95.949  123.390 1.00 44.05  ? 253 ALA A N   1 
ATOM 666  C CA  . ALA A 1 221 ? 108.792 94.930  123.798 1.00 47.19  ? 253 ALA A CA  1 
ATOM 667  C C   . ALA A 1 221 ? 108.796 94.760  125.310 1.00 50.61  ? 253 ALA A C   1 
ATOM 668  O O   . ALA A 1 221 ? 109.752 95.127  126.008 1.00 64.21  ? 253 ALA A O   1 
ATOM 669  C CB  . ALA A 1 221 ? 109.086 93.590  123.116 1.00 56.34  ? 253 ALA A CB  1 
ATOM 670  N N   . ILE A 1 222 ? 107.705 94.177  125.799 1.00 40.05  ? 254 ILE A N   1 
ATOM 671  C CA  . ILE A 1 222 ? 107.543 93.827  127.202 1.00 43.37  ? 254 ILE A CA  1 
ATOM 672  C C   . ILE A 1 222 ? 107.462 92.310  127.288 1.00 49.35  ? 254 ILE A C   1 
ATOM 673  O O   . ILE A 1 222 ? 106.557 91.697  126.711 1.00 62.97  ? 254 ILE A O   1 
ATOM 674  C CB  . ILE A 1 222 ? 106.296 94.481  127.815 1.00 49.40  ? 254 ILE A CB  1 
ATOM 675  C CG1 . ILE A 1 222 ? 106.471 95.996  127.888 1.00 47.65  ? 254 ILE A CG1 1 
ATOM 676  C CG2 . ILE A 1 222 ? 106.020 93.918  129.192 1.00 54.55  ? 254 ILE A CG2 1 
ATOM 677  C CD1 . ILE A 1 222 ? 105.200 96.735  128.203 1.00 51.55  ? 254 ILE A CD1 1 
ATOM 678  N N   . ILE A 1 223 ? 108.405 91.709  128.003 1.00 40.28  ? 255 ILE A N   1 
ATOM 679  C CA  . ILE A 1 223 ? 108.462 90.264  128.174 1.00 38.38  ? 255 ILE A CA  1 
ATOM 680  C C   . ILE A 1 223 ? 107.722 89.913  129.458 1.00 40.64  ? 255 ILE A C   1 
ATOM 681  O O   . ILE A 1 223 ? 108.199 90.197  130.559 1.00 59.37  ? 255 ILE A O   1 
ATOM 682  C CB  . ILE A 1 223 ? 109.908 89.760  128.210 1.00 43.16  ? 255 ILE A CB  1 
ATOM 683  C CG1 . ILE A 1 223 ? 110.680 90.280  127.002 1.00 47.33  ? 255 ILE A CG1 1 
ATOM 684  C CG2 . ILE A 1 223 ? 109.942 88.250  128.255 1.00 48.86  ? 255 ILE A CG2 1 
ATOM 685  C CD1 . ILE A 1 223 ? 112.120 89.852  126.980 1.00 53.71  ? 255 ILE A CD1 1 
ATOM 686  N N   . PHE A 1 224 ? 106.560 89.288  129.315 1.00 35.28  ? 256 PHE A N   1 
ATOM 687  C CA  . PHE A 1 224 ? 105.734 88.880  130.443 1.00 45.90  ? 256 PHE A CA  1 
ATOM 688  C C   . PHE A 1 224 ? 105.962 87.396  130.699 1.00 51.00  ? 256 PHE A C   1 
ATOM 689  O O   . PHE A 1 224 ? 105.589 86.556  129.874 1.00 61.75  ? 256 PHE A O   1 
ATOM 690  C CB  . PHE A 1 224 ? 104.261 89.167  130.162 1.00 48.95  ? 256 PHE A CB  1 
ATOM 691  C CG  . PHE A 1 224 ? 103.397 89.164  131.386 1.00 49.33  ? 256 PHE A CG  1 
ATOM 692  C CD1 . PHE A 1 224 ? 102.865 87.983  131.867 1.00 51.47  ? 256 PHE A CD1 1 
ATOM 693  C CD2 . PHE A 1 224 ? 103.109 90.337  132.050 1.00 55.27  ? 256 PHE A CD2 1 
ATOM 694  C CE1 . PHE A 1 224 ? 102.072 87.975  132.990 1.00 47.34  ? 256 PHE A CE1 1 
ATOM 695  C CE2 . PHE A 1 224 ? 102.316 90.329  133.173 1.00 58.42  ? 256 PHE A CE2 1 
ATOM 696  C CZ  . PHE A 1 224 ? 101.798 89.147  133.642 1.00 50.00  ? 256 PHE A CZ  1 
ATOM 697  N N   . VAL A 1 225 ? 106.561 87.074  131.841 1.00 43.46  ? 257 VAL A N   1 
ATOM 698  C CA  . VAL A 1 225 ? 106.838 85.691  132.214 1.00 41.38  ? 257 VAL A CA  1 
ATOM 699  C C   . VAL A 1 225 ? 105.774 85.239  133.200 1.00 48.23  ? 257 VAL A C   1 
ATOM 700  O O   . VAL A 1 225 ? 105.623 85.832  134.275 1.00 58.14  ? 257 VAL A O   1 
ATOM 701  C CB  . VAL A 1 225 ? 108.244 85.542  132.812 1.00 50.74  ? 257 VAL A CB  1 
ATOM 702  C CG1 . VAL A 1 225 ? 108.497 84.104  133.200 1.00 52.88  ? 257 VAL A CG1 1 
ATOM 703  C CG2 . VAL A 1 225 ? 109.285 86.010  131.819 1.00 55.12  ? 257 VAL A CG2 1 
ATOM 704  N N   . VAL A 1 226 ? 105.034 84.190  132.846 1.00 50.27  ? 258 VAL A N   1 
ATOM 705  C CA  . VAL A 1 226 ? 103.928 83.705  133.660 1.00 48.56  ? 258 VAL A CA  1 
ATOM 706  C C   . VAL A 1 226 ? 104.126 82.223  133.941 1.00 53.32  ? 258 VAL A C   1 
ATOM 707  O O   . VAL A 1 226 ? 104.461 81.449  133.037 1.00 65.56  ? 258 VAL A O   1 
ATOM 708  C CB  . VAL A 1 226 ? 102.565 83.963  132.988 1.00 58.55  ? 258 VAL A CB  1 
ATOM 709  C CG1 . VAL A 1 226 ? 102.485 83.286  131.630 1.00 62.07  ? 258 VAL A CG1 1 
ATOM 710  C CG2 . VAL A 1 226 ? 101.438 83.491  133.887 1.00 60.58  ? 258 VAL A CG2 1 
ATOM 711  N N   . ASP A 1 227 ? 103.948 81.839  135.200 1.00 70.14  ? 259 ASP A N   1 
ATOM 712  C CA  . ASP A 1 227 ? 104.034 80.438  135.584 1.00 72.87  ? 259 ASP A CA  1 
ATOM 713  C C   . ASP A 1 227 ? 102.781 79.695  135.143 1.00 78.43  ? 259 ASP A C   1 
ATOM 714  O O   . ASP A 1 227 ? 101.659 80.164  135.357 1.00 84.92  ? 259 ASP A O   1 
ATOM 715  C CB  . ASP A 1 227 ? 104.219 80.315  137.092 1.00 74.52  ? 259 ASP A CB  1 
ATOM 716  C CG  . ASP A 1 227 ? 104.066 78.895  137.577 1.00 81.14  ? 259 ASP A CG  1 
ATOM 717  O OD1 . ASP A 1 227 ? 105.019 78.108  137.428 1.00 80.16  ? 259 ASP A OD1 1 
ATOM 718  O OD2 . ASP A 1 227 ? 102.986 78.562  138.103 1.00 85.10  ? 259 ASP A OD2 1 
ATOM 719  N N   . SER A 1 228 ? 102.974 78.532  134.529 1.00 73.77  ? 260 SER A N   1 
ATOM 720  C CA  . SER A 1 228 ? 101.879 77.747  133.984 1.00 72.61  ? 260 SER A CA  1 
ATOM 721  C C   . SER A 1 228 ? 101.547 76.528  134.830 1.00 74.80  ? 260 SER A C   1 
ATOM 722  O O   . SER A 1 228 ? 100.771 75.676  134.389 1.00 84.12  ? 260 SER A O   1 
ATOM 723  C CB  . SER A 1 228 ? 102.209 77.316  132.557 1.00 78.35  ? 260 SER A CB  1 
ATOM 724  O OG  . SER A 1 228 ? 101.041 76.960  131.844 1.00 84.94  ? 260 SER A OG  1 
ATOM 725  N N   . SER A 1 229 ? 102.110 76.422  136.033 1.00 73.91  ? 261 SER A N   1 
ATOM 726  C CA  . SER A 1 229 ? 101.888 75.261  136.881 1.00 76.65  ? 261 SER A CA  1 
ATOM 727  C C   . SER A 1 229 ? 101.076 75.549  138.133 1.00 78.83  ? 261 SER A C   1 
ATOM 728  O O   . SER A 1 229 ? 100.400 74.643  138.626 1.00 82.93  ? 261 SER A O   1 
ATOM 729  C CB  . SER A 1 229 ? 103.229 74.642  137.299 1.00 80.75  ? 261 SER A CB  1 
ATOM 730  O OG  . SER A 1 229 ? 103.047 73.679  138.322 1.00 85.82  ? 261 SER A OG  1 
ATOM 731  N N   . ASP A 1 230 ? 101.118 76.771  138.657 1.00 81.34  ? 262 ASP A N   1 
ATOM 732  C CA  . ASP A 1 230 ? 100.405 77.126  139.879 1.00 81.91  ? 262 ASP A CA  1 
ATOM 733  C C   . ASP A 1 230 ? 99.001  77.584  139.507 1.00 81.99  ? 262 ASP A C   1 
ATOM 734  O O   . ASP A 1 230 ? 98.814  78.696  139.005 1.00 85.72  ? 262 ASP A O   1 
ATOM 735  C CB  . ASP A 1 230 ? 101.148 78.213  140.652 1.00 80.56  ? 262 ASP A CB  1 
ATOM 736  N N   . TYR A 1 231 ? 98.014  76.724  139.759 1.00 78.32  ? 263 TYR A N   1 
ATOM 737  C CA  . TYR A 1 231 ? 96.637  77.064  139.425 1.00 78.67  ? 263 TYR A CA  1 
ATOM 738  C C   . TYR A 1 231 ? 96.068  78.109  140.374 1.00 81.56  ? 263 TYR A C   1 
ATOM 739  O O   . TYR A 1 231 ? 95.122  78.819  140.016 1.00 87.17  ? 263 TYR A O   1 
ATOM 740  C CB  . TYR A 1 231 ? 95.769  75.808  139.446 1.00 78.99  ? 263 TYR A CB  1 
ATOM 741  C CG  . TYR A 1 231 ? 96.164  74.766  138.429 1.00 82.93  ? 263 TYR A CG  1 
ATOM 742  C CD1 . TYR A 1 231 ? 96.710  75.131  137.210 1.00 82.95  ? 263 TYR A CD1 1 
ATOM 743  C CD2 . TYR A 1 231 ? 95.987  73.416  138.689 1.00 84.07  ? 263 TYR A CD2 1 
ATOM 744  C CE1 . TYR A 1 231 ? 97.069  74.181  136.278 1.00 83.54  ? 263 TYR A CE1 1 
ATOM 745  C CE2 . TYR A 1 231 ? 96.345  72.460  137.764 1.00 82.32  ? 263 TYR A CE2 1 
ATOM 746  C CZ  . TYR A 1 231 ? 96.885  72.848  136.561 1.00 83.57  ? 263 TYR A CZ  1 
ATOM 747  O OH  . TYR A 1 231 ? 97.243  71.896  135.635 1.00 86.08  ? 263 TYR A OH  1 
ATOM 748  N N   . ASN A 1 232 ? 96.620  78.214  141.584 1.00 67.25  ? 264 ASN A N   1 
ATOM 749  C CA  . ASN A 1 232 ? 96.079  79.150  142.563 1.00 67.66  ? 264 ASN A CA  1 
ATOM 750  C C   . ASN A 1 232 ? 96.255  80.593  142.111 1.00 71.19  ? 264 ASN A C   1 
ATOM 751  O O   . ASN A 1 232 ? 95.366  81.427  142.315 1.00 72.16  ? 264 ASN A O   1 
ATOM 752  C CB  . ASN A 1 232 ? 96.740  78.927  143.922 1.00 69.73  ? 264 ASN A CB  1 
ATOM 753  N N   . ARG A 1 233 ? 97.389  80.908  141.494 1.00 77.55  ? 265 ARG A N   1 
ATOM 754  C CA  . ARG A 1 233 ? 97.732  82.274  141.116 1.00 78.59  ? 265 ARG A CA  1 
ATOM 755  C C   . ARG A 1 233 ? 97.695  82.483  139.604 1.00 77.90  ? 265 ARG A C   1 
ATOM 756  O O   . ARG A 1 233 ? 98.557  83.152  139.034 1.00 81.68  ? 265 ARG A O   1 
ATOM 757  C CB  . ARG A 1 233 ? 99.101  82.657  141.669 1.00 78.67  ? 265 ARG A CB  1 
ATOM 758  C CG  . ARG A 1 233 ? 99.149  82.762  143.182 1.00 80.26  ? 265 ARG A CG  1 
ATOM 759  C CD  . ARG A 1 233 ? 100.472 82.253  143.729 1.00 80.39  ? 265 ARG A CD  1 
ATOM 760  N NE  . ARG A 1 233 ? 101.607 83.024  143.237 1.00 81.50  ? 265 ARG A NE  1 
ATOM 761  C CZ  . ARG A 1 233 ? 101.863 84.285  143.561 1.00 83.75  ? 265 ARG A CZ  1 
ATOM 762  N NH1 . ARG A 1 233 ? 101.092 84.954  144.403 1.00 80.89  ? 265 ARG A NH1 1 
ATOM 763  N NH2 . ARG A 1 233 ? 102.923 84.888  143.032 1.00 84.26  ? 265 ARG A NH2 1 
ATOM 764  N N   . LEU A 1 234 ? 96.696  81.910  138.935 1.00 70.11  ? 266 LEU A N   1 
ATOM 765  C CA  . LEU A 1 234 ? 96.498  82.168  137.515 1.00 68.60  ? 266 LEU A CA  1 
ATOM 766  C C   . LEU A 1 234 ? 95.577  83.356  137.268 1.00 74.81  ? 266 LEU A C   1 
ATOM 767  O O   . LEU A 1 234 ? 95.809  84.137  136.338 1.00 80.89  ? 266 LEU A O   1 
ATOM 768  C CB  . LEU A 1 234 ? 95.935  80.927  136.824 1.00 71.12  ? 266 LEU A CB  1 
ATOM 769  C CG  . LEU A 1 234 ? 96.940  80.083  136.042 1.00 74.15  ? 266 LEU A CG  1 
ATOM 770  C CD1 . LEU A 1 234 ? 96.238  78.926  135.353 1.00 76.73  ? 266 LEU A CD1 1 
ATOM 771  C CD2 . LEU A 1 234 ? 97.673  80.944  135.031 1.00 75.48  ? 266 LEU A CD2 1 
ATOM 772  N N   . GLN A 1 235 ? 94.534  83.507  138.086 1.00 74.90  ? 267 GLN A N   1 
ATOM 773  C CA  . GLN A 1 235 ? 93.620  84.631  137.920 1.00 75.29  ? 267 GLN A CA  1 
ATOM 774  C C   . GLN A 1 235 ? 94.322  85.959  138.181 1.00 77.45  ? 267 GLN A C   1 
ATOM 775  O O   . GLN A 1 235 ? 94.074  86.948  137.479 1.00 80.04  ? 267 GLN A O   1 
ATOM 776  C CB  . GLN A 1 235 ? 92.415  84.465  138.843 1.00 71.89  ? 267 GLN A CB  1 
ATOM 777  C CG  . GLN A 1 235 ? 91.229  85.327  138.467 1.00 74.57  ? 267 GLN A CG  1 
ATOM 778  C CD  . GLN A 1 235 ? 90.762  85.080  137.051 1.00 79.76  ? 267 GLN A CD  1 
ATOM 779  O OE1 . GLN A 1 235 ? 90.889  85.943  136.183 1.00 80.86  ? 267 GLN A OE1 1 
ATOM 780  N NE2 . GLN A 1 235 ? 90.216  83.896  136.808 1.00 77.58  ? 267 GLN A NE2 1 
ATOM 781  N N   . GLU A 1 236 ? 95.201  86.002  139.185 1.00 71.80  ? 268 GLU A N   1 
ATOM 782  C CA  . GLU A 1 236 ? 95.974  87.214  139.437 1.00 72.79  ? 268 GLU A CA  1 
ATOM 783  C C   . GLU A 1 236 ? 96.883  87.542  138.259 1.00 74.43  ? 268 GLU A C   1 
ATOM 784  O O   . GLU A 1 236 ? 97.032  88.712  137.884 1.00 76.92  ? 268 GLU A O   1 
ATOM 785  C CB  . GLU A 1 236 ? 96.787  87.061  140.721 1.00 67.66  ? 268 GLU A CB  1 
ATOM 786  N N   . ALA A 1 237 ? 97.502  86.521  137.663 1.00 64.66  ? 269 ALA A N   1 
ATOM 787  C CA  . ALA A 1 237 ? 98.338  86.748  136.490 1.00 65.68  ? 269 ALA A CA  1 
ATOM 788  C C   . ALA A 1 237 ? 97.518  87.290  135.328 1.00 72.27  ? 269 ALA A C   1 
ATOM 789  O O   . ALA A 1 237 ? 97.964  88.195  134.609 1.00 79.01  ? 269 ALA A O   1 
ATOM 790  C CB  . ALA A 1 237 ? 99.045  85.454  136.093 1.00 65.95  ? 269 ALA A CB  1 
ATOM 791  N N   . LEU A 1 238 ? 96.315  86.747  135.124 1.00 61.85  ? 270 LEU A N   1 
ATOM 792  C CA  . LEU A 1 238 ? 95.453  87.253  134.062 1.00 60.59  ? 270 LEU A CA  1 
ATOM 793  C C   . LEU A 1 238 ? 95.064  88.703  134.314 1.00 64.45  ? 270 LEU A C   1 
ATOM 794  O O   . LEU A 1 238 ? 95.032  89.516  133.383 1.00 69.60  ? 270 LEU A O   1 
ATOM 795  C CB  . LEU A 1 238 ? 94.208  86.379  133.931 1.00 61.92  ? 270 LEU A CB  1 
ATOM 796  C CG  . LEU A 1 238 ? 94.410  85.009  133.286 1.00 66.11  ? 270 LEU A CG  1 
ATOM 797  C CD1 . LEU A 1 238 ? 93.118  84.213  133.308 1.00 65.76  ? 270 LEU A CD1 1 
ATOM 798  C CD2 . LEU A 1 238 ? 94.923  85.159  131.868 1.00 69.03  ? 270 LEU A CD2 1 
ATOM 799  N N   . ASN A 1 239 ? 94.763  89.046  135.568 1.00 67.02  ? 271 ASN A N   1 
ATOM 800  C CA  . ASN A 1 239 ? 94.432  90.429  135.892 1.00 66.46  ? 271 ASN A CA  1 
ATOM 801  C C   . ASN A 1 239 ? 95.611  91.356  135.625 1.00 70.45  ? 271 ASN A C   1 
ATOM 802  O O   . ASN A 1 239 ? 95.433  92.467  135.112 1.00 74.30  ? 271 ASN A O   1 
ATOM 803  C CB  . ASN A 1 239 ? 93.986  90.538  137.348 1.00 65.34  ? 271 ASN A CB  1 
ATOM 804  C CG  . ASN A 1 239 ? 92.686  89.814  137.612 1.00 71.40  ? 271 ASN A CG  1 
ATOM 805  O OD1 . ASN A 1 239 ? 91.929  89.521  136.690 1.00 74.11  ? 271 ASN A OD1 1 
ATOM 806  N ND2 . ASN A 1 239 ? 92.418  89.524  138.878 1.00 72.40  ? 271 ASN A ND2 1 
ATOM 807  N N   . ASP A 1 240 ? 96.823  90.921  135.976 1.00 65.08  ? 272 ASP A N   1 
ATOM 808  C CA  . ASP A 1 240 ? 98.003  91.742  135.724 1.00 62.48  ? 272 ASP A CA  1 
ATOM 809  C C   . ASP A 1 240 ? 98.215  91.949  134.229 1.00 66.21  ? 272 ASP A C   1 
ATOM 810  O O   . ASP A 1 240 ? 98.531  93.061  133.781 1.00 74.27  ? 272 ASP A O   1 
ATOM 811  C CB  . ASP A 1 240 ? 99.230  91.090  136.364 1.00 69.16  ? 272 ASP A CB  1 
ATOM 812  C CG  . ASP A 1 240 ? 100.460 91.982  136.334 1.00 77.25  ? 272 ASP A CG  1 
ATOM 813  O OD1 . ASP A 1 240 ? 100.391 93.104  135.791 1.00 76.61  ? 272 ASP A OD1 1 
ATOM 814  O OD2 . ASP A 1 240 ? 101.508 91.554  136.861 1.00 79.86  ? 272 ASP A OD2 1 
ATOM 815  N N   . PHE A 1 241 ? 98.039  90.889  133.438 1.00 57.96  ? 273 PHE A N   1 
ATOM 816  C CA  . PHE A 1 241 ? 98.190  91.025  131.994 1.00 62.01  ? 273 PHE A CA  1 
ATOM 817  C C   . PHE A 1 241 ? 97.134  91.958  131.419 1.00 65.95  ? 273 PHE A C   1 
ATOM 818  O O   . PHE A 1 241 ? 97.422  92.749  130.514 1.00 66.70  ? 273 PHE A O   1 
ATOM 819  C CB  . PHE A 1 241 ? 98.124  89.657  131.321 1.00 59.63  ? 273 PHE A CB  1 
ATOM 820  C CG  . PHE A 1 241 ? 98.282  89.711  129.833 1.00 54.72  ? 273 PHE A CG  1 
ATOM 821  C CD1 . PHE A 1 241 ? 99.480  90.093  129.268 1.00 57.17  ? 273 PHE A CD1 1 
ATOM 822  C CD2 . PHE A 1 241 ? 97.236  89.377  129.000 1.00 57.81  ? 273 PHE A CD2 1 
ATOM 823  C CE1 . PHE A 1 241 ? 99.630  90.145  127.904 1.00 59.46  ? 273 PHE A CE1 1 
ATOM 824  C CE2 . PHE A 1 241 ? 97.382  89.426  127.634 1.00 61.28  ? 273 PHE A CE2 1 
ATOM 825  C CZ  . PHE A 1 241 ? 98.582  89.811  127.087 1.00 60.80  ? 273 PHE A CZ  1 
ATOM 826  N N   . LYS A 1 242 ? 95.904  91.880  131.930 1.00 63.62  ? 274 LYS A N   1 
ATOM 827  C CA  . LYS A 1 242 ? 94.859  92.794  131.482 1.00 56.41  ? 274 LYS A CA  1 
ATOM 828  C C   . LYS A 1 242 ? 95.202  94.235  131.833 1.00 56.17  ? 274 LYS A C   1 
ATOM 829  O O   . LYS A 1 242 ? 94.966  95.149  131.036 1.00 63.85  ? 274 LYS A O   1 
ATOM 830  C CB  . LYS A 1 242 ? 93.517  92.395  132.091 1.00 55.15  ? 274 LYS A CB  1 
ATOM 831  C CG  . LYS A 1 242 ? 92.368  93.304  131.710 1.00 57.54  ? 274 LYS A CG  1 
ATOM 832  C CD  . LYS A 1 242 ? 91.046  92.560  131.720 1.00 60.09  ? 274 LYS A CD  1 
ATOM 833  C CE  . LYS A 1 242 ? 90.868  91.761  132.995 1.00 61.21  ? 274 LYS A CE  1 
ATOM 834  N NZ  . LYS A 1 242 ? 89.578  91.020  133.006 1.00 61.49  ? 274 LYS A NZ  1 
ATOM 835  N N   . SER A 1 243 ? 95.755  94.456  133.026 1.00 50.39  ? 275 SER A N   1 
ATOM 836  C CA  . SER A 1 243 ? 96.142  95.805  133.426 1.00 52.96  ? 275 SER A CA  1 
ATOM 837  C C   . SER A 1 243 ? 97.229  96.362  132.518 1.00 54.78  ? 275 SER A C   1 
ATOM 838  O O   . SER A 1 243 ? 97.187  97.536  132.135 1.00 60.03  ? 275 SER A O   1 
ATOM 839  C CB  . SER A 1 243 ? 96.611  95.808  134.879 1.00 58.09  ? 275 SER A CB  1 
ATOM 840  O OG  . SER A 1 243 ? 97.023  97.103  135.275 1.00 58.99  ? 275 SER A OG  1 
ATOM 841  N N   . ILE A 1 244 ? 98.218  95.539  132.170 1.00 58.30  ? 276 ILE A N   1 
ATOM 842  C CA  . ILE A 1 244 ? 99.290  96.014  131.299 1.00 55.29  ? 276 ILE A CA  1 
ATOM 843  C C   . ILE A 1 244 ? 98.770  96.256  129.886 1.00 61.54  ? 276 ILE A C   1 
ATOM 844  O O   . ILE A 1 244 ? 99.160  97.226  129.225 1.00 59.69  ? 276 ILE A O   1 
ATOM 845  C CB  . ILE A 1 244 ? 100.465 95.023  131.306 1.00 56.87  ? 276 ILE A CB  1 
ATOM 846  C CG1 . ILE A 1 244 ? 101.065 94.924  132.704 1.00 66.34  ? 276 ILE A CG1 1 
ATOM 847  C CG2 . ILE A 1 244 ? 101.533 95.457  130.327 1.00 58.39  ? 276 ILE A CG2 1 
ATOM 848  C CD1 . ILE A 1 244 ? 102.041 93.793  132.851 1.00 64.21  ? 276 ILE A CD1 1 
ATOM 849  N N   . TRP A 1 245 ? 97.884  95.384  129.402 1.00 61.66  ? 277 TRP A N   1 
ATOM 850  C CA  . TRP A 1 245 ? 97.425  95.471  128.019 1.00 54.40  ? 277 TRP A CA  1 
ATOM 851  C C   . TRP A 1 245 ? 96.628  96.743  127.762 1.00 58.71  ? 277 TRP A C   1 
ATOM 852  O O   . TRP A 1 245 ? 96.792  97.381  126.716 1.00 64.28  ? 277 TRP A O   1 
ATOM 853  C CB  . TRP A 1 245 ? 96.587  94.243  127.675 1.00 56.58  ? 277 TRP A CB  1 
ATOM 854  C CG  . TRP A 1 245 ? 96.439  94.012  126.213 1.00 60.59  ? 277 TRP A CG  1 
ATOM 855  C CD1 . TRP A 1 245 ? 95.305  94.147  125.477 1.00 62.10  ? 277 TRP A CD1 1 
ATOM 856  C CD2 . TRP A 1 245 ? 97.463  93.604  125.303 1.00 62.40  ? 277 TRP A CD2 1 
ATOM 857  N NE1 . TRP A 1 245 ? 95.556  93.850  124.163 1.00 65.37  ? 277 TRP A NE1 1 
ATOM 858  C CE2 . TRP A 1 245 ? 96.876  93.512  124.030 1.00 58.17  ? 277 TRP A CE2 1 
ATOM 859  C CE3 . TRP A 1 245 ? 98.821  93.306  125.441 1.00 66.30  ? 277 TRP A CE3 1 
ATOM 860  C CZ2 . TRP A 1 245 ? 97.594  93.133  122.905 1.00 57.06  ? 277 TRP A CZ2 1 
ATOM 861  C CZ3 . TRP A 1 245 ? 99.533  92.934  124.321 1.00 65.09  ? 277 TRP A CZ3 1 
ATOM 862  C CH2 . TRP A 1 245 ? 98.920  92.851  123.069 1.00 61.38  ? 277 TRP A CH2 1 
ATOM 863  N N   . ASN A 1 246 ? 95.760  97.130  128.696 1.00 58.63  ? 278 ASN A N   1 
ATOM 864  C CA  . ASN A 1 246 ? 94.868  98.265  128.511 1.00 53.54  ? 278 ASN A CA  1 
ATOM 865  C C   . ASN A 1 246 ? 95.381  99.538  129.176 1.00 54.23  ? 278 ASN A C   1 
ATOM 866  O O   . ASN A 1 246 ? 94.581  100.411 129.527 1.00 62.07  ? 278 ASN A O   1 
ATOM 867  C CB  . ASN A 1 246 ? 93.473  97.927  129.033 1.00 55.95  ? 278 ASN A CB  1 
ATOM 868  C CG  . ASN A 1 246 ? 92.788  96.862  128.211 1.00 56.40  ? 278 ASN A CG  1 
ATOM 869  O OD1 . ASN A 1 246 ? 92.431  97.088  127.057 1.00 62.11  ? 278 ASN A OD1 1 
ATOM 870  N ND2 . ASN A 1 246 ? 92.588  95.695  128.805 1.00 56.16  ? 278 ASN A ND2 1 
ATOM 871  N N   . ASN A 1 247 ? 96.690  99.662  129.365 1.00 54.71  ? 279 ASN A N   1 
ATOM 872  C CA  . ASN A 1 247 ? 97.252  100.892 129.899 1.00 52.61  ? 279 ASN A CA  1 
ATOM 873  C C   . ASN A 1 247 ? 97.263  101.978 128.829 1.00 63.37  ? 279 ASN A C   1 
ATOM 874  O O   . ASN A 1 247 ? 97.432  101.708 127.638 1.00 67.07  ? 279 ASN A O   1 
ATOM 875  C CB  . ASN A 1 247 ? 98.667  100.650 130.419 1.00 59.38  ? 279 ASN A CB  1 
ATOM 876  C CG  . ASN A 1 247 ? 99.123  101.718 131.385 1.00 61.48  ? 279 ASN A CG  1 
ATOM 877  O OD1 . ASN A 1 247 ? 99.439  102.836 130.986 1.00 63.74  ? 279 ASN A OD1 1 
ATOM 878  N ND2 . ASN A 1 247 ? 99.161  101.380 132.665 1.00 60.02  ? 279 ASN A ND2 1 
ATOM 879  N N   . ARG A 1 248 ? 97.075  103.224 129.269 1.00 63.48  ? 280 ARG A N   1 
ATOM 880  C CA  . ARG A 1 248 ? 96.977  104.336 128.329 1.00 59.74  ? 280 ARG A CA  1 
ATOM 881  C C   . ARG A 1 248 ? 98.308  104.611 127.642 1.00 58.03  ? 280 ARG A C   1 
ATOM 882  O O   . ARG A 1 248 ? 98.342  104.916 126.444 1.00 58.54  ? 280 ARG A O   1 
ATOM 883  C CB  . ARG A 1 248 ? 96.479  105.587 129.048 1.00 54.04  ? 280 ARG A CB  1 
ATOM 884  N N   . TRP A 1 249 ? 99.410  104.515 128.376 1.00 66.17  ? 281 TRP A N   1 
ATOM 885  C CA  . TRP A 1 249 ? 100.726 104.841 127.845 1.00 66.53  ? 281 TRP A CA  1 
ATOM 886  C C   . TRP A 1 249 ? 101.380 103.679 127.112 1.00 69.78  ? 281 TRP A C   1 
ATOM 887  O O   . TRP A 1 249 ? 102.419 103.875 126.476 1.00 72.78  ? 281 TRP A O   1 
ATOM 888  C CB  . TRP A 1 249 ? 101.641 105.317 128.975 1.00 67.62  ? 281 TRP A CB  1 
ATOM 889  C CG  . TRP A 1 249 ? 101.094 106.488 129.714 1.00 69.62  ? 281 TRP A CG  1 
ATOM 890  C CD1 . TRP A 1 249 ? 100.568 106.491 130.969 1.00 70.26  ? 281 TRP A CD1 1 
ATOM 891  C CD2 . TRP A 1 249 ? 101.010 107.834 129.240 1.00 70.32  ? 281 TRP A CD2 1 
ATOM 892  N NE1 . TRP A 1 249 ? 100.161 107.756 131.308 1.00 67.96  ? 281 TRP A NE1 1 
ATOM 893  C CE2 . TRP A 1 249 ? 100.422 108.599 130.262 1.00 69.10  ? 281 TRP A CE2 1 
ATOM 894  C CE3 . TRP A 1 249 ? 101.375 108.466 128.050 1.00 71.71  ? 281 TRP A CE3 1 
ATOM 895  C CZ2 . TRP A 1 249 ? 100.192 109.963 130.131 1.00 70.19  ? 281 TRP A CZ2 1 
ATOM 896  C CZ3 . TRP A 1 249 ? 101.145 109.819 127.922 1.00 71.19  ? 281 TRP A CZ3 1 
ATOM 897  C CH2 . TRP A 1 249 ? 100.560 110.553 128.956 1.00 69.86  ? 281 TRP A CH2 1 
ATOM 898  N N   . LEU A 1 250 ? 100.799 102.487 127.174 1.00 65.09  ? 282 LEU A N   1 
ATOM 899  C CA  . LEU A 1 250 ? 101.341 101.300 126.530 1.00 56.52  ? 282 LEU A CA  1 
ATOM 900  C C   . LEU A 1 250 ? 100.410 100.815 125.427 1.00 63.07  ? 282 LEU A C   1 
ATOM 901  O O   . LEU A 1 250 ? 100.161 99.617  125.278 1.00 68.17  ? 282 LEU A O   1 
ATOM 902  C CB  . LEU A 1 250 ? 101.586 100.193 127.552 1.00 60.11  ? 282 LEU A CB  1 
ATOM 903  C CG  . LEU A 1 250 ? 102.519 100.543 128.709 1.00 62.03  ? 282 LEU A CG  1 
ATOM 904  C CD1 . LEU A 1 250 ? 102.770 99.334  129.582 1.00 64.70  ? 282 LEU A CD1 1 
ATOM 905  C CD2 . LEU A 1 250 ? 103.821 101.093 128.181 1.00 65.06  ? 282 LEU A CD2 1 
ATOM 906  N N   . ARG A 1 251 ? 99.883  101.748 124.639 1.00 61.83  ? 283 ARG A N   1 
ATOM 907  C CA  . ARG A 1 251 ? 98.957  101.435 123.561 1.00 58.37  ? 283 ARG A CA  1 
ATOM 908  C C   . ARG A 1 251 ? 99.655  101.155 122.239 1.00 64.10  ? 283 ARG A C   1 
ATOM 909  O O   . ARG A 1 251 ? 98.976  100.958 121.227 1.00 71.39  ? 283 ARG A O   1 
ATOM 910  C CB  . ARG A 1 251 ? 97.955  102.577 123.378 1.00 58.12  ? 283 ARG A CB  1 
ATOM 911  N N   . THR A 1 252 ? 100.989 101.142 122.217 1.00 67.85  ? 284 THR A N   1 
ATOM 912  C CA  . THR A 1 252 ? 101.723 100.829 120.997 1.00 67.45  ? 284 THR A CA  1 
ATOM 913  C C   . THR A 1 252 ? 102.920 99.919  121.258 1.00 74.13  ? 284 THR A C   1 
ATOM 914  O O   . THR A 1 252 ? 103.816 99.833  120.410 1.00 79.91  ? 284 THR A O   1 
ATOM 915  C CB  . THR A 1 252 ? 102.189 102.112 120.304 1.00 69.79  ? 284 THR A CB  1 
ATOM 916  O OG1 . THR A 1 252 ? 102.758 101.790 119.030 1.00 73.53  ? 284 THR A OG1 1 
ATOM 917  C CG2 . THR A 1 252 ? 103.220 102.840 121.154 1.00 71.94  ? 284 THR A CG2 1 
ATOM 918  N N   . ILE A 1 253 ? 102.953 99.227  122.395 1.00 67.48  ? 285 ILE A N   1 
ATOM 919  C CA  . ILE A 1 253 ? 104.074 98.379  122.785 1.00 61.31  ? 285 ILE A CA  1 
ATOM 920  C C   . ILE A 1 253 ? 103.600 96.934  122.812 1.00 62.05  ? 285 ILE A C   1 
ATOM 921  O O   . ILE A 1 253 ? 102.581 96.620  123.438 1.00 63.73  ? 285 ILE A O   1 
ATOM 922  C CB  . ILE A 1 253 ? 104.646 98.797  124.150 1.00 59.22  ? 285 ILE A CB  1 
ATOM 923  C CG1 . ILE A 1 253 ? 105.216 100.211 124.078 1.00 63.19  ? 285 ILE A CG1 1 
ATOM 924  C CG2 . ILE A 1 253 ? 105.712 97.818  124.605 1.00 65.17  ? 285 ILE A CG2 1 
ATOM 925  C CD1 . ILE A 1 253 ? 106.031 100.483 122.837 1.00 62.33  ? 285 ILE A CD1 1 
ATOM 926  N N   . SER A 1 254 ? 104.340 96.057  122.141 1.00 52.69  ? 286 SER A N   1 
ATOM 927  C CA  . SER A 1 254 ? 103.985 94.652  122.033 1.00 48.08  ? 286 SER A CA  1 
ATOM 928  C C   . SER A 1 254 ? 104.494 93.860  123.234 1.00 56.33  ? 286 SER A C   1 
ATOM 929  O O   . SER A 1 254 ? 105.436 94.259  123.927 1.00 67.54  ? 286 SER A O   1 
ATOM 930  C CB  . SER A 1 254 ? 104.544 94.059  120.743 1.00 53.92  ? 286 SER A CB  1 
ATOM 931  O OG  . SER A 1 254 ? 103.992 94.706  119.613 1.00 61.27  ? 286 SER A OG  1 
ATOM 932  N N   . VAL A 1 255 ? 103.854 92.717  123.468 1.00 46.66  ? 287 VAL A N   1 
ATOM 933  C CA  . VAL A 1 255 ? 104.131 91.866  124.618 1.00 42.53  ? 287 VAL A CA  1 
ATOM 934  C C   . VAL A 1 255 ? 104.508 90.477  124.122 1.00 53.26  ? 287 VAL A C   1 
ATOM 935  O O   . VAL A 1 255 ? 103.771 89.870  123.336 1.00 60.76  ? 287 VAL A O   1 
ATOM 936  C CB  . VAL A 1 255 ? 102.924 91.792  125.569 1.00 45.19  ? 287 VAL A CB  1 
ATOM 937  C CG1 . VAL A 1 255 ? 103.185 90.799  126.679 1.00 46.75  ? 287 VAL A CG1 1 
ATOM 938  C CG2 . VAL A 1 255 ? 102.624 93.158  126.144 1.00 52.62  ? 287 VAL A CG2 1 
ATOM 939  N N   . ILE A 1 256 ? 105.651 89.982  124.580 1.00 47.93  ? 288 ILE A N   1 
ATOM 940  C CA  . ILE A 1 256 ? 106.090 88.616  124.329 1.00 37.50  ? 288 ILE A CA  1 
ATOM 941  C C   . ILE A 1 256 ? 105.808 87.803  125.582 1.00 44.09  ? 288 ILE A C   1 
ATOM 942  O O   . ILE A 1 256 ? 106.315 88.119  126.665 1.00 58.72  ? 288 ILE A O   1 
ATOM 943  C CB  . ILE A 1 256 ? 107.578 88.560  123.956 1.00 39.75  ? 288 ILE A CB  1 
ATOM 944  C CG1 . ILE A 1 256 ? 107.886 89.555  122.841 1.00 44.80  ? 288 ILE A CG1 1 
ATOM 945  C CG2 . ILE A 1 256 ? 107.962 87.165  123.531 1.00 49.66  ? 288 ILE A CG2 1 
ATOM 946  C CD1 . ILE A 1 256 ? 109.347 89.863  122.694 1.00 47.35  ? 288 ILE A CD1 1 
ATOM 947  N N   . LEU A 1 257 ? 105.007 86.755  125.439 1.00 44.92  ? 289 LEU A N   1 
ATOM 948  C CA  . LEU A 1 257 ? 104.511 85.980  126.566 1.00 46.54  ? 289 LEU A CA  1 
ATOM 949  C C   . LEU A 1 257 ? 105.315 84.694  126.704 1.00 53.40  ? 289 LEU A C   1 
ATOM 950  O O   . LEU A 1 257 ? 105.516 83.974  125.721 1.00 61.50  ? 289 LEU A O   1 
ATOM 951  C CB  . LEU A 1 257 ? 103.029 85.662  126.379 1.00 45.14  ? 289 LEU A CB  1 
ATOM 952  C CG  . LEU A 1 257 ? 102.173 85.501  127.628 1.00 47.54  ? 289 LEU A CG  1 
ATOM 953  C CD1 . LEU A 1 257 ? 102.047 86.824  128.358 1.00 56.08  ? 289 LEU A CD1 1 
ATOM 954  C CD2 . LEU A 1 257 ? 100.812 84.967  127.251 1.00 50.57  ? 289 LEU A CD2 1 
ATOM 955  N N   . PHE A 1 258 ? 105.768 84.409  127.922 1.00 47.29  ? 290 PHE A N   1 
ATOM 956  C CA  . PHE A 1 258 ? 106.572 83.227  128.218 1.00 43.08  ? 290 PHE A CA  1 
ATOM 957  C C   . PHE A 1 258 ? 105.820 82.378  129.236 1.00 52.21  ? 290 PHE A C   1 
ATOM 958  O O   . PHE A 1 258 ? 105.783 82.711  130.426 1.00 65.04  ? 290 PHE A O   1 
ATOM 959  C CB  . PHE A 1 258 ? 107.945 83.620  128.749 1.00 47.82  ? 290 PHE A CB  1 
ATOM 960  C CG  . PHE A 1 258 ? 108.963 83.881  127.680 1.00 48.57  ? 290 PHE A CG  1 
ATOM 961  C CD1 . PHE A 1 258 ? 108.714 84.790  126.673 1.00 51.30  ? 290 PHE A CD1 1 
ATOM 962  C CD2 . PHE A 1 258 ? 110.174 83.224  127.691 1.00 55.52  ? 290 PHE A CD2 1 
ATOM 963  C CE1 . PHE A 1 258 ? 109.654 85.031  125.696 1.00 51.07  ? 290 PHE A CE1 1 
ATOM 964  C CE2 . PHE A 1 258 ? 111.112 83.464  126.718 1.00 53.91  ? 290 PHE A CE2 1 
ATOM 965  C CZ  . PHE A 1 258 ? 110.850 84.368  125.720 1.00 47.38  ? 290 PHE A CZ  1 
ATOM 966  N N   . LEU A 1 259 ? 105.229 81.281  128.771 1.00 61.09  ? 291 LEU A N   1 
ATOM 967  C CA  . LEU A 1 259 ? 104.588 80.301  129.647 1.00 65.91  ? 291 LEU A CA  1 
ATOM 968  C C   . LEU A 1 259 ? 105.686 79.429  130.241 1.00 69.37  ? 291 LEU A C   1 
ATOM 969  O O   . LEU A 1 259 ? 106.016 78.362  129.723 1.00 74.81  ? 291 LEU A O   1 
ATOM 970  C CB  . LEU A 1 259 ? 103.566 79.471  128.880 1.00 65.07  ? 291 LEU A CB  1 
ATOM 971  C CG  . LEU A 1 259 ? 102.129 79.981  128.747 1.00 66.96  ? 291 LEU A CG  1 
ATOM 972  C CD1 . LEU A 1 259 ? 101.476 80.082  130.112 1.00 69.69  ? 291 LEU A CD1 1 
ATOM 973  C CD2 . LEU A 1 259 ? 102.061 81.308  128.019 1.00 66.36  ? 291 LEU A CD2 1 
ATOM 974  N N   . ASN A 1 260 ? 106.257 79.889  131.348 1.00 66.26  ? 292 ASN A N   1 
ATOM 975  C CA  . ASN A 1 260 ? 107.454 79.277  131.896 1.00 62.21  ? 292 ASN A CA  1 
ATOM 976  C C   . ASN A 1 260 ? 107.122 78.012  132.682 1.00 58.77  ? 292 ASN A C   1 
ATOM 977  O O   . ASN A 1 260 ? 105.989 77.794  133.117 1.00 68.40  ? 292 ASN A O   1 
ATOM 978  C CB  . ASN A 1 260 ? 108.192 80.270  132.792 1.00 72.19  ? 292 ASN A CB  1 
ATOM 979  C CG  . ASN A 1 260 ? 109.598 79.829  133.118 1.00 73.18  ? 292 ASN A CG  1 
ATOM 980  O OD1 . ASN A 1 260 ? 110.050 78.778  132.669 1.00 76.34  ? 292 ASN A OD1 1 
ATOM 981  N ND2 . ASN A 1 260 ? 110.301 80.631  133.905 1.00 72.30  ? 292 ASN A ND2 1 
ATOM 982  N N   . LYS A 1 261 ? 108.143 77.177  132.856 1.00 71.02  ? 293 LYS A N   1 
ATOM 983  C CA  . LYS A 1 261 ? 108.075 75.951  133.649 1.00 76.72  ? 293 LYS A CA  1 
ATOM 984  C C   . LYS A 1 261 ? 106.969 75.020  133.153 1.00 75.82  ? 293 LYS A C   1 
ATOM 985  O O   . LYS A 1 261 ? 106.013 74.704  133.860 1.00 77.01  ? 293 LYS A O   1 
ATOM 986  C CB  . LYS A 1 261 ? 107.915 76.270  135.137 1.00 81.34  ? 293 LYS A CB  1 
ATOM 987  C CG  . LYS A 1 261 ? 109.236 76.242  135.894 1.00 83.22  ? 293 LYS A CG  1 
ATOM 988  C CD  . LYS A 1 261 ? 109.323 77.316  136.964 1.00 79.64  ? 293 LYS A CD  1 
ATOM 989  C CE  . LYS A 1 261 ? 108.034 77.434  137.745 1.00 82.15  ? 293 LYS A CE  1 
ATOM 990  N NZ  . LYS A 1 261 ? 108.172 78.364  138.897 1.00 79.88  ? 293 LYS A NZ  1 
ATOM 991  N N   . GLN A 1 262 ? 107.126 74.577  131.908 1.00 80.92  ? 294 GLN A N   1 
ATOM 992  C CA  . GLN A 1 262 ? 106.242 73.577  131.326 1.00 81.15  ? 294 GLN A CA  1 
ATOM 993  C C   . GLN A 1 262 ? 106.552 72.164  131.795 1.00 84.48  ? 294 GLN A C   1 
ATOM 994  O O   . GLN A 1 262 ? 105.703 71.279  131.644 1.00 88.74  ? 294 GLN A O   1 
ATOM 995  C CB  . GLN A 1 262 ? 106.319 73.622  129.798 1.00 78.71  ? 294 GLN A CB  1 
ATOM 996  C CG  . GLN A 1 262 ? 105.835 74.916  129.187 1.00 82.58  ? 294 GLN A CG  1 
ATOM 997  C CD  . GLN A 1 262 ? 104.384 75.194  129.502 1.00 88.63  ? 294 GLN A CD  1 
ATOM 998  O OE1 . GLN A 1 262 ? 104.067 76.100  130.270 1.00 91.75  ? 294 GLN A OE1 1 
ATOM 999  N NE2 . GLN A 1 262 ? 103.490 74.411  128.912 1.00 86.38  ? 294 GLN A NE2 1 
ATOM 1000 N N   . ASP A 1 263 ? 107.742 71.930  132.353 1.00 77.91  ? 295 ASP A N   1 
ATOM 1001 C CA  . ASP A 1 263 ? 108.076 70.597  132.841 1.00 76.74  ? 295 ASP A CA  1 
ATOM 1002 C C   . ASP A 1 263 ? 107.215 70.207  134.032 1.00 80.11  ? 295 ASP A C   1 
ATOM 1003 O O   . ASP A 1 263 ? 106.803 69.048  134.144 1.00 82.14  ? 295 ASP A O   1 
ATOM 1004 C CB  . ASP A 1 263 ? 109.556 70.527  133.209 1.00 77.76  ? 295 ASP A CB  1 
ATOM 1005 N N   . LEU A 1 264 ? 106.933 71.152  134.926 1.00 84.14  ? 296 LEU A N   1 
ATOM 1006 C CA  . LEU A 1 264 ? 106.078 70.885  136.073 1.00 83.15  ? 296 LEU A CA  1 
ATOM 1007 C C   . LEU A 1 264 ? 104.618 70.705  135.690 1.00 83.30  ? 296 LEU A C   1 
ATOM 1008 O O   . LEU A 1 264 ? 103.907 69.942  136.355 1.00 89.56  ? 296 LEU A O   1 
ATOM 1009 C CB  . LEU A 1 264 ? 106.195 72.014  137.102 1.00 84.08  ? 296 LEU A CB  1 
ATOM 1010 C CG  . LEU A 1 264 ? 107.365 71.979  138.091 1.00 85.45  ? 296 LEU A CG  1 
ATOM 1011 C CD1 . LEU A 1 264 ? 107.261 70.758  138.995 1.00 85.54  ? 296 LEU A CD1 1 
ATOM 1012 C CD2 . LEU A 1 264 ? 108.719 72.026  137.395 1.00 84.48  ? 296 LEU A CD2 1 
ATOM 1013 N N   . LEU A 1 265 ? 104.156 71.390  134.642 1.00 80.62  ? 297 LEU A N   1 
ATOM 1014 C CA  . LEU A 1 265 ? 102.781 71.209  134.193 1.00 82.64  ? 297 LEU A CA  1 
ATOM 1015 C C   . LEU A 1 265 ? 102.544 69.783  133.724 1.00 85.12  ? 297 LEU A C   1 
ATOM 1016 O O   . LEU A 1 265 ? 101.504 69.188  134.023 1.00 87.61  ? 297 LEU A O   1 
ATOM 1017 C CB  . LEU A 1 265 ? 102.454 72.199  133.077 1.00 80.91  ? 297 LEU A CB  1 
ATOM 1018 C CG  . LEU A 1 265 ? 100.977 72.308  132.704 1.00 82.28  ? 297 LEU A CG  1 
ATOM 1019 C CD1 . LEU A 1 265 ? 100.118 72.405  133.951 1.00 83.44  ? 297 LEU A CD1 1 
ATOM 1020 C CD2 . LEU A 1 265 ? 100.741 73.498  131.793 1.00 82.42  ? 297 LEU A CD2 1 
ATOM 1021 N N   . ALA A 1 266 ? 103.497 69.219  132.982 1.00 87.61  ? 298 ALA A N   1 
ATOM 1022 C CA  . ALA A 1 266 ? 103.372 67.831  132.556 1.00 87.92  ? 298 ALA A CA  1 
ATOM 1023 C C   . ALA A 1 266 ? 103.394 66.886  133.748 1.00 85.75  ? 298 ALA A C   1 
ATOM 1024 O O   . ALA A 1 266 ? 102.627 65.917  133.793 1.00 90.38  ? 298 ALA A O   1 
ATOM 1025 C CB  . ALA A 1 266 ? 104.487 67.481  131.570 1.00 87.71  ? 298 ALA A CB  1 
ATOM 1026 N N   . GLU A 1 267 ? 104.266 67.148  134.723 1.00 77.86  ? 299 GLU A N   1 
ATOM 1027 C CA  . GLU A 1 267 ? 104.348 66.280  135.892 1.00 80.72  ? 299 GLU A CA  1 
ATOM 1028 C C   . GLU A 1 267 ? 103.056 66.294  136.695 1.00 83.74  ? 299 GLU A C   1 
ATOM 1029 O O   . GLU A 1 267 ? 102.597 65.240  137.148 1.00 83.97  ? 299 GLU A O   1 
ATOM 1030 C CB  . GLU A 1 267 ? 105.525 66.697  136.773 1.00 81.00  ? 299 GLU A CB  1 
ATOM 1031 N N   . LYS A 1 268 ? 102.456 67.466  136.881 1.00 92.73  ? 300 LYS A N   1 
ATOM 1032 C CA  . LYS A 1 268 ? 101.219 67.564  137.646 1.00 91.21  ? 300 LYS A CA  1 
ATOM 1033 C C   . LYS A 1 268 ? 100.000 67.093  136.868 1.00 94.46  ? 300 LYS A C   1 
ATOM 1034 O O   . LYS A 1 268 ? 99.057  66.568  137.472 1.00 97.37  ? 300 LYS A O   1 
ATOM 1035 C CB  . LYS A 1 268 ? 101.001 69.004  138.116 1.00 90.68  ? 300 LYS A CB  1 
ATOM 1036 C CG  . LYS A 1 268 ? 99.940  69.145  139.194 1.00 92.33  ? 300 LYS A CG  1 
ATOM 1037 C CD  . LYS A 1 268 ? 99.548  70.596  139.410 1.00 94.97  ? 300 LYS A CD  1 
ATOM 1038 C CE  . LYS A 1 268 ? 100.753 71.514  139.329 1.00 95.29  ? 300 LYS A CE  1 
ATOM 1039 N NZ  . LYS A 1 268 ? 101.571 71.461  140.570 1.00 93.50  ? 300 LYS A NZ  1 
ATOM 1040 N N   . VAL A 1 269 ? 99.991  67.269  135.545 1.00 89.41  ? 301 VAL A N   1 
ATOM 1041 C CA  . VAL A 1 269 ? 98.847  66.848  134.742 1.00 88.01  ? 301 VAL A CA  1 
ATOM 1042 C C   . VAL A 1 269 ? 98.697  65.333  134.782 1.00 92.03  ? 301 VAL A C   1 
ATOM 1043 O O   . VAL A 1 269 ? 97.593  64.805  134.952 1.00 93.14  ? 301 VAL A O   1 
ATOM 1044 C CB  . VAL A 1 269 ? 98.987  67.363  133.299 1.00 85.90  ? 301 VAL A CB  1 
ATOM 1045 N N   . LEU A 1 270 ? 99.807  64.610  134.631 1.00 95.77  ? 302 LEU A N   1 
ATOM 1046 C CA  . LEU A 1 270 ? 99.797  63.148  134.661 1.00 94.60  ? 302 LEU A CA  1 
ATOM 1047 C C   . LEU A 1 270 ? 99.812  62.679  136.116 1.00 95.18  ? 302 LEU A C   1 
ATOM 1048 O O   . LEU A 1 270 ? 100.734 62.012  136.590 1.00 96.98  ? 302 LEU A O   1 
ATOM 1049 C CB  . LEU A 1 270 ? 100.975 62.584  133.879 1.00 93.61  ? 302 LEU A CB  1 
ATOM 1050 C CG  . LEU A 1 270 ? 100.904 62.563  132.349 1.00 95.02  ? 302 LEU A CG  1 
ATOM 1051 C CD1 . LEU A 1 270 ? 101.026 63.957  131.748 1.00 94.66  ? 302 LEU A CD1 1 
ATOM 1052 C CD2 . LEU A 1 270 ? 101.976 61.642  131.785 1.00 96.49  ? 302 LEU A CD2 1 
ATOM 1053 N N   . ALA A 1 271 ? 98.752  63.043  136.830 1.00 93.35  ? 303 ALA A N   1 
ATOM 1054 C CA  . ALA A 1 271 ? 98.621  62.711  138.242 1.00 97.38  ? 303 ALA A CA  1 
ATOM 1055 C C   . ALA A 1 271 ? 97.141  62.717  138.598 1.00 98.37  ? 303 ALA A C   1 
ATOM 1056 O O   . ALA A 1 271 ? 96.278  62.956  137.749 1.00 94.13  ? 303 ALA A O   1 
ATOM 1057 C CB  . ALA A 1 271 ? 99.417  63.682  139.117 1.00 96.29  ? 303 ALA A CB  1 
ATOM 1058 N N   . GLY A 1 272 ? 96.853  62.452  139.868 1.00 108.74 ? 304 GLY A N   1 
ATOM 1059 C CA  . GLY A 1 272 ? 95.480  62.384  140.325 1.00 108.28 ? 304 GLY A CA  1 
ATOM 1060 C C   . GLY A 1 272 ? 95.138  63.392  141.401 1.00 108.68 ? 304 GLY A C   1 
ATOM 1061 O O   . GLY A 1 272 ? 93.972  63.766  141.557 1.00 110.50 ? 304 GLY A O   1 
ATOM 1062 N N   . LYS A 1 273 ? 96.139  63.843  142.150 1.00 109.08 ? 305 LYS A N   1 
ATOM 1063 C CA  . LYS A 1 273 ? 95.912  64.778  143.252 1.00 110.84 ? 305 LYS A CA  1 
ATOM 1064 C C   . LYS A 1 273 ? 95.858  66.220  142.760 1.00 109.91 ? 305 LYS A C   1 
ATOM 1065 O O   . LYS A 1 273 ? 96.518  67.109  143.296 1.00 110.48 ? 305 LYS A O   1 
ATOM 1066 C CB  . LYS A 1 273 ? 96.993  64.601  144.312 1.00 109.11 ? 305 LYS A CB  1 
ATOM 1067 N N   . SER A 1 274 ? 95.045  66.456  141.733 1.00 103.11 ? 306 SER A N   1 
ATOM 1068 C CA  . SER A 1 274 ? 94.870  67.769  141.127 1.00 102.85 ? 306 SER A CA  1 
ATOM 1069 C C   . SER A 1 274 ? 93.754  67.668  140.099 1.00 103.55 ? 306 SER A C   1 
ATOM 1070 O O   . SER A 1 274 ? 93.448  66.584  139.595 1.00 103.03 ? 306 SER A O   1 
ATOM 1071 C CB  . SER A 1 274 ? 96.153  68.276  140.462 1.00 101.78 ? 306 SER A CB  1 
ATOM 1072 O OG  . SER A 1 274 ? 95.942  69.530  139.839 1.00 101.31 ? 306 SER A OG  1 
ATOM 1073 N N   . LYS A 1 275 ? 93.149  68.813  139.796 1.00 99.39  ? 307 LYS A N   1 
ATOM 1074 C CA  . LYS A 1 275 ? 92.133  68.887  138.750 1.00 97.95  ? 307 LYS A CA  1 
ATOM 1075 C C   . LYS A 1 275 ? 92.019  70.333  138.302 1.00 96.66  ? 307 LYS A C   1 
ATOM 1076 O O   . LYS A 1 275 ? 91.557  71.182  139.072 1.00 101.57 ? 307 LYS A O   1 
ATOM 1077 C CB  . LYS A 1 275 ? 90.788  68.366  139.254 1.00 96.35  ? 307 LYS A CB  1 
ATOM 1078 N N   . ILE A 1 276 ? 92.438  70.618  137.068 1.00 80.03  ? 308 ILE A N   1 
ATOM 1079 C CA  . ILE A 1 276 ? 92.334  71.980  136.556 1.00 82.80  ? 308 ILE A CA  1 
ATOM 1080 C C   . ILE A 1 276 ? 90.877  72.372  136.364 1.00 88.97  ? 308 ILE A C   1 
ATOM 1081 O O   . ILE A 1 276 ? 90.543  73.563  136.350 1.00 89.84  ? 308 ILE A O   1 
ATOM 1082 C CB  . ILE A 1 276 ? 93.140  72.126  135.253 1.00 80.91  ? 308 ILE A CB  1 
ATOM 1083 C CG1 . ILE A 1 276 ? 93.248  73.596  134.847 1.00 82.60  ? 308 ILE A CG1 1 
ATOM 1084 C CG2 . ILE A 1 276 ? 92.518  71.304  134.144 1.00 84.19  ? 308 ILE A CG2 1 
ATOM 1085 C CD1 . ILE A 1 276 ? 94.276  73.858  133.775 1.00 84.24  ? 308 ILE A CD1 1 
ATOM 1086 N N   . GLU A 1 277 ? 89.984  71.389  136.226 1.00 94.30  ? 309 GLU A N   1 
ATOM 1087 C CA  . GLU A 1 277 ? 88.566  71.686  136.068 1.00 91.48  ? 309 GLU A CA  1 
ATOM 1088 C C   . GLU A 1 277 ? 87.967  72.319  137.314 1.00 91.55  ? 309 GLU A C   1 
ATOM 1089 O O   . GLU A 1 277 ? 86.916  72.962  137.224 1.00 91.28  ? 309 GLU A O   1 
ATOM 1090 C CB  . GLU A 1 277 ? 87.800  70.413  135.712 1.00 89.90  ? 309 GLU A CB  1 
ATOM 1091 N N   . ASP A 1 278 ? 88.605  72.150  138.473 1.00 96.57  ? 310 ASP A N   1 
ATOM 1092 C CA  . ASP A 1 278 ? 88.057  72.710  139.703 1.00 97.35  ? 310 ASP A CA  1 
ATOM 1093 C C   . ASP A 1 278 ? 88.142  74.231  139.713 1.00 99.58  ? 310 ASP A C   1 
ATOM 1094 O O   . ASP A 1 278 ? 87.158  74.913  140.023 1.00 101.83 ? 310 ASP A O   1 
ATOM 1095 C CB  . ASP A 1 278 ? 88.784  72.124  140.913 1.00 94.78  ? 310 ASP A CB  1 
ATOM 1096 N N   . TYR A 1 279 ? 89.309  74.785  139.376 1.00 89.40  ? 311 TYR A N   1 
ATOM 1097 C CA  . TYR A 1 279 ? 89.506  76.226  139.490 1.00 83.85  ? 311 TYR A CA  1 
ATOM 1098 C C   . TYR A 1 279 ? 88.786  76.972  138.372 1.00 84.68  ? 311 TYR A C   1 
ATOM 1099 O O   . TYR A 1 279 ? 88.148  78.005  138.602 1.00 90.21  ? 311 TYR A O   1 
ATOM 1100 C CB  . TYR A 1 279 ? 90.999  76.552  139.488 1.00 84.96  ? 311 TYR A CB  1 
ATOM 1101 C CG  . TYR A 1 279 ? 91.673  76.350  140.826 1.00 87.11  ? 311 TYR A CG  1 
ATOM 1102 C CD1 . TYR A 1 279 ? 91.369  75.256  141.623 1.00 85.75  ? 311 TYR A CD1 1 
ATOM 1103 C CD2 . TYR A 1 279 ? 92.614  77.253  141.292 1.00 89.19  ? 311 TYR A CD2 1 
ATOM 1104 C CE1 . TYR A 1 279 ? 91.982  75.067  142.841 1.00 84.08  ? 311 TYR A CE1 1 
ATOM 1105 C CE2 . TYR A 1 279 ? 93.232  77.073  142.511 1.00 89.15  ? 311 TYR A CE2 1 
ATOM 1106 C CZ  . TYR A 1 279 ? 92.912  75.979  143.281 1.00 87.12  ? 311 TYR A CZ  1 
ATOM 1107 O OH  . TYR A 1 279 ? 93.527  75.796  144.498 1.00 90.11  ? 311 TYR A OH  1 
ATOM 1108 N N   . PHE A 1 280 ? 88.882  76.459  137.151 1.00 81.96  ? 312 PHE A N   1 
ATOM 1109 C CA  . PHE A 1 280 ? 88.161  77.024  136.019 1.00 88.38  ? 312 PHE A CA  1 
ATOM 1110 C C   . PHE A 1 280 ? 87.035  76.084  135.611 1.00 87.90  ? 312 PHE A C   1 
ATOM 1111 O O   . PHE A 1 280 ? 87.297  74.964  135.154 1.00 89.71  ? 312 PHE A O   1 
ATOM 1112 C CB  . PHE A 1 280 ? 89.100  77.269  134.838 1.00 87.51  ? 312 PHE A CB  1 
ATOM 1113 C CG  . PHE A 1 280 ? 90.145  78.313  135.095 1.00 85.04  ? 312 PHE A CG  1 
ATOM 1114 C CD1 . PHE A 1 280 ? 89.834  79.656  135.004 1.00 90.29  ? 312 PHE A CD1 1 
ATOM 1115 C CD2 . PHE A 1 280 ? 91.436  77.953  135.424 1.00 78.30  ? 312 PHE A CD2 1 
ATOM 1116 C CE1 . PHE A 1 280 ? 90.793  80.618  135.234 1.00 91.45  ? 312 PHE A CE1 1 
ATOM 1117 C CE2 . PHE A 1 280 ? 92.396  78.910  135.657 1.00 82.49  ? 312 PHE A CE2 1 
ATOM 1118 C CZ  . PHE A 1 280 ? 92.075  80.243  135.562 1.00 88.74  ? 312 PHE A CZ  1 
ATOM 1119 N N   . PRO A 1 281 ? 85.775  76.495  135.758 1.00 89.33  ? 313 PRO A N   1 
ATOM 1120 C CA  . PRO A 1 281 ? 84.659  75.613  135.402 1.00 89.20  ? 313 PRO A CA  1 
ATOM 1121 C C   . PRO A 1 281 ? 84.414  75.496  133.909 1.00 89.55  ? 313 PRO A C   1 
ATOM 1122 O O   . PRO A 1 281 ? 83.611  74.652  133.497 1.00 89.80  ? 313 PRO A O   1 
ATOM 1123 C CB  . PRO A 1 281 ? 83.468  76.277  136.103 1.00 89.69  ? 313 PRO A CB  1 
ATOM 1124 C CG  . PRO A 1 281 ? 83.813  77.726  136.118 1.00 89.57  ? 313 PRO A CG  1 
ATOM 1125 C CD  . PRO A 1 281 ? 85.318  77.830  136.182 1.00 90.62  ? 313 PRO A CD  1 
ATOM 1126 N N   . GLU A 1 282 ? 85.078  76.309  133.092 1.00 85.78  ? 314 GLU A N   1 
ATOM 1127 C CA  . GLU A 1 282 ? 84.878  76.284  131.650 1.00 86.20  ? 314 GLU A CA  1 
ATOM 1128 C C   . GLU A 1 282 ? 85.780  75.287  130.939 1.00 87.14  ? 314 GLU A C   1 
ATOM 1129 O O   . GLU A 1 282 ? 85.729  75.206  129.707 1.00 87.53  ? 314 GLU A O   1 
ATOM 1130 C CB  . GLU A 1 282 ? 85.100  77.680  131.066 1.00 84.80  ? 314 GLU A CB  1 
ATOM 1131 N N   . PHE A 1 283 ? 86.606  74.536  131.670 1.00 80.73  ? 315 PHE A N   1 
ATOM 1132 C CA  . PHE A 1 283 ? 87.544  73.631  131.015 1.00 80.36  ? 315 PHE A CA  1 
ATOM 1133 C C   . PHE A 1 283 ? 86.827  72.494  130.301 1.00 84.34  ? 315 PHE A C   1 
ATOM 1134 O O   . PHE A 1 283 ? 87.208  72.121  129.185 1.00 87.41  ? 315 PHE A O   1 
ATOM 1135 C CB  . PHE A 1 283 ? 88.542  73.070  132.023 1.00 83.30  ? 315 PHE A CB  1 
ATOM 1136 C CG  . PHE A 1 283 ? 89.674  72.322  131.387 1.00 82.41  ? 315 PHE A CG  1 
ATOM 1137 C CD1 . PHE A 1 283 ? 90.443  72.916  130.404 1.00 84.37  ? 315 PHE A CD1 1 
ATOM 1138 C CD2 . PHE A 1 283 ? 89.955  71.019  131.753 1.00 81.60  ? 315 PHE A CD2 1 
ATOM 1139 C CE1 . PHE A 1 283 ? 91.480  72.229  129.809 1.00 85.36  ? 315 PHE A CE1 1 
ATOM 1140 C CE2 . PHE A 1 283 ? 90.989  70.328  131.160 1.00 84.83  ? 315 PHE A CE2 1 
ATOM 1141 C CZ  . PHE A 1 283 ? 91.753  70.934  130.188 1.00 86.09  ? 315 PHE A CZ  1 
ATOM 1142 N N   . ALA A 1 284 ? 85.787  71.928  130.915 1.00 85.79  ? 316 ALA A N   1 
ATOM 1143 C CA  . ALA A 1 284 ? 85.134  70.775  130.306 1.00 85.08  ? 316 ALA A CA  1 
ATOM 1144 C C   . ALA A 1 284 ? 84.148  71.220  129.236 1.00 87.56  ? 316 ALA A C   1 
ATOM 1145 O O   . ALA A 1 284 ? 83.008  70.749  129.185 1.00 89.66  ? 316 ALA A O   1 
ATOM 1146 C CB  . ALA A 1 284 ? 84.425  69.935  131.369 1.00 82.26  ? 316 ALA A CB  1 
ATOM 1147 N N   . ARG A 1 285 ? 84.595  72.133  128.376 1.00 84.21  ? 317 ARG A N   1 
ATOM 1148 C CA  . ARG A 1 285 ? 83.900  72.473  127.144 1.00 84.04  ? 317 ARG A CA  1 
ATOM 1149 C C   . ARG A 1 285 ? 84.896  72.785  126.037 1.00 85.07  ? 317 ARG A C   1 
ATOM 1150 O O   . ARG A 1 285 ? 84.486  73.254  124.968 1.00 87.92  ? 317 ARG A O   1 
ATOM 1151 C CB  . ARG A 1 285 ? 82.954  73.661  127.353 1.00 83.20  ? 317 ARG A CB  1 
ATOM 1152 N N   . TYR A 1 286 ? 86.183  72.543  126.264 1.00 81.07  ? 318 TYR A N   1 
ATOM 1153 C CA  . TYR A 1 286 ? 87.252  72.996  125.388 1.00 82.02  ? 318 TYR A CA  1 
ATOM 1154 C C   . TYR A 1 286 ? 87.809  71.820  124.603 1.00 82.97  ? 318 TYR A C   1 
ATOM 1155 O O   . TYR A 1 286 ? 88.112  70.770  125.178 1.00 84.17  ? 318 TYR A O   1 
ATOM 1156 C CB  . TYR A 1 286 ? 88.366  73.661  126.197 1.00 78.17  ? 318 TYR A CB  1 
ATOM 1157 C CG  . TYR A 1 286 ? 89.326  74.478  125.370 1.00 76.03  ? 318 TYR A CG  1 
ATOM 1158 C CD1 . TYR A 1 286 ? 88.969  75.729  124.896 1.00 80.31  ? 318 TYR A CD1 1 
ATOM 1159 C CD2 . TYR A 1 286 ? 90.586  73.997  125.061 1.00 77.19  ? 318 TYR A CD2 1 
ATOM 1160 C CE1 . TYR A 1 286 ? 89.843  76.479  124.139 1.00 83.72  ? 318 TYR A CE1 1 
ATOM 1161 C CE2 . TYR A 1 286 ? 91.464  74.737  124.305 1.00 80.70  ? 318 TYR A CE2 1 
ATOM 1162 C CZ  . TYR A 1 286 ? 91.088  75.978  123.846 1.00 84.23  ? 318 TYR A CZ  1 
ATOM 1163 O OH  . TYR A 1 286 ? 91.963  76.721  123.090 1.00 82.28  ? 318 TYR A OH  1 
ATOM 1164 N N   . THR A 1 287 ? 87.938  72.001  123.294 1.00 84.16  ? 319 THR A N   1 
ATOM 1165 C CA  . THR A 1 287 ? 88.584  71.039  122.417 1.00 81.88  ? 319 THR A CA  1 
ATOM 1166 C C   . THR A 1 287 ? 89.874  71.647  121.887 1.00 80.63  ? 319 THR A C   1 
ATOM 1167 O O   . THR A 1 287 ? 89.935  72.850  121.616 1.00 86.00  ? 319 THR A O   1 
ATOM 1168 C CB  . THR A 1 287 ? 87.670  70.650  121.254 1.00 85.19  ? 319 THR A CB  1 
ATOM 1169 O OG1 . THR A 1 287 ? 87.725  71.663  120.242 1.00 84.22  ? 319 THR A OG1 1 
ATOM 1170 C CG2 . THR A 1 287 ? 86.235  70.502  121.736 1.00 82.52  ? 319 THR A CG2 1 
ATOM 1171 N N   . THR A 1 288 ? 90.901  70.818  121.753 1.00 70.66  ? 320 THR A N   1 
ATOM 1172 C CA  . THR A 1 288 ? 92.202  71.324  121.346 1.00 71.62  ? 320 THR A CA  1 
ATOM 1173 C C   . THR A 1 288 ? 92.110  71.959  119.959 1.00 74.37  ? 320 THR A C   1 
ATOM 1174 O O   . THR A 1 288 ? 91.401  71.448  119.083 1.00 81.01  ? 320 THR A O   1 
ATOM 1175 C CB  . THR A 1 288 ? 93.246  70.203  121.360 1.00 75.61  ? 320 THR A CB  1 
ATOM 1176 O OG1 . THR A 1 288 ? 94.547  70.754  121.119 1.00 78.99  ? 320 THR A OG1 1 
ATOM 1177 C CG2 . THR A 1 288 ? 92.939  69.134  120.322 1.00 77.45  ? 320 THR A CG2 1 
ATOM 1178 N N   . PRO A 1 289 ? 92.766  73.097  119.742 1.00 80.41  ? 321 PRO A N   1 
ATOM 1179 C CA  . PRO A 1 289 ? 92.709  73.737  118.424 1.00 81.62  ? 321 PRO A CA  1 
ATOM 1180 C C   . PRO A 1 289 ? 93.384  72.886  117.362 1.00 88.68  ? 321 PRO A C   1 
ATOM 1181 O O   . PRO A 1 289 ? 94.313  72.123  117.639 1.00 89.83  ? 321 PRO A O   1 
ATOM 1182 C CB  . PRO A 1 289 ? 93.452  75.060  118.639 1.00 83.14  ? 321 PRO A CB  1 
ATOM 1183 C CG  . PRO A 1 289 ? 94.305  74.829  119.835 1.00 86.31  ? 321 PRO A CG  1 
ATOM 1184 C CD  . PRO A 1 289 ? 93.538  73.889  120.710 1.00 86.19  ? 321 PRO A CD  1 
ATOM 1185 N N   . GLU A 1 290 ? 92.896  73.022  116.126 1.00 97.42  ? 322 GLU A N   1 
ATOM 1186 C CA  . GLU A 1 290 ? 93.446  72.244  115.022 1.00 96.39  ? 322 GLU A CA  1 
ATOM 1187 C C   . GLU A 1 290 ? 94.908  72.589  114.773 1.00 98.49  ? 322 GLU A C   1 
ATOM 1188 O O   . GLU A 1 290 ? 95.735  71.698  114.547 1.00 99.26  ? 322 GLU A O   1 
ATOM 1189 C CB  . GLU A 1 290 ? 92.619  72.473  113.757 1.00 93.92  ? 322 GLU A CB  1 
ATOM 1190 N N   . ASP A 1 291 ? 95.247  73.874  114.813 1.00 100.82 ? 323 ASP A N   1 
ATOM 1191 C CA  . ASP A 1 291 ? 96.616  74.322  114.571 1.00 99.49  ? 323 ASP A CA  1 
ATOM 1192 C C   . ASP A 1 291 ? 97.435  74.089  115.833 1.00 99.67  ? 323 ASP A C   1 
ATOM 1193 O O   . ASP A 1 291 ? 97.487  74.940  116.723 1.00 99.54  ? 323 ASP A O   1 
ATOM 1194 C CB  . ASP A 1 291 ? 96.636  75.789  114.159 1.00 98.05  ? 323 ASP A CB  1 
ATOM 1195 N N   . ALA A 1 292 ? 98.080  72.929  115.912 1.00 97.92  ? 324 ALA A N   1 
ATOM 1196 C CA  . ALA A 1 292 ? 98.928  72.595  117.045 1.00 97.74  ? 324 ALA A CA  1 
ATOM 1197 C C   . ALA A 1 292 ? 100.080 71.736  116.554 1.00 99.67  ? 324 ALA A C   1 
ATOM 1198 O O   . ALA A 1 292 ? 99.963  71.032  115.547 1.00 101.49 ? 324 ALA A O   1 
ATOM 1199 C CB  . ALA A 1 292 ? 98.147  71.866  118.143 1.00 96.60  ? 324 ALA A CB  1 
ATOM 1200 N N   . THR A 1 293 ? 101.195 71.796  117.276 1.00 106.31 ? 325 THR A N   1 
ATOM 1201 C CA  . THR A 1 293 ? 102.411 71.064  116.924 1.00 108.37 ? 325 THR A CA  1 
ATOM 1202 C C   . THR A 1 293 ? 102.932 70.302  118.139 1.00 108.45 ? 325 THR A C   1 
ATOM 1203 O O   . THR A 1 293 ? 104.003 70.605  118.679 1.00 109.90 ? 325 THR A O   1 
ATOM 1204 C CB  . THR A 1 293 ? 103.462 72.016  116.342 1.00 111.81 ? 325 THR A CB  1 
ATOM 1205 O OG1 . THR A 1 293 ? 104.651 71.289  116.001 1.00 112.13 ? 325 THR A OG1 1 
ATOM 1206 C CG2 . THR A 1 293 ? 103.774 73.189  117.285 1.00 109.61 ? 325 THR A CG2 1 
ATOM 1207 N N   . PRO A 1 294 ? 102.204 69.276  118.581 1.00 112.49 ? 326 PRO A N   1 
ATOM 1208 C CA  . PRO A 1 294 ? 102.648 68.512  119.754 1.00 112.31 ? 326 PRO A CA  1 
ATOM 1209 C C   . PRO A 1 294 ? 103.923 67.743  119.446 1.00 112.45 ? 326 PRO A C   1 
ATOM 1210 O O   . PRO A 1 294 ? 103.995 66.998  118.466 1.00 113.30 ? 326 PRO A O   1 
ATOM 1211 C CB  . PRO A 1 294 ? 101.473 67.565  120.032 1.00 111.54 ? 326 PRO A CB  1 
ATOM 1212 C CG  . PRO A 1 294 ? 100.326 68.096  119.217 1.00 112.22 ? 326 PRO A CG  1 
ATOM 1213 C CD  . PRO A 1 294 ? 100.954 68.736  118.026 1.00 112.49 ? 326 PRO A CD  1 
ATOM 1214 N N   . GLU A 1 295 ? 104.933 67.932  120.290 1.00 115.65 ? 327 GLU A N   1 
ATOM 1215 C CA  . GLU A 1 295 ? 106.174 67.199  120.127 1.00 115.90 ? 327 GLU A CA  1 
ATOM 1216 C C   . GLU A 1 295 ? 105.939 65.712  120.387 1.00 118.88 ? 327 GLU A C   1 
ATOM 1217 O O   . GLU A 1 295 ? 105.089 65.345  121.203 1.00 117.92 ? 327 GLU A O   1 
ATOM 1218 C CB  . GLU A 1 295 ? 107.243 67.734  121.077 1.00 113.33 ? 327 GLU A CB  1 
ATOM 1219 N N   . PRO A 1 296 ? 106.666 64.838  119.693 1.00 128.14 ? 328 PRO A N   1 
ATOM 1220 C CA  . PRO A 1 296 ? 106.485 63.398  119.908 1.00 127.25 ? 328 PRO A CA  1 
ATOM 1221 C C   . PRO A 1 296 ? 106.800 63.006  121.343 1.00 127.59 ? 328 PRO A C   1 
ATOM 1222 O O   . PRO A 1 296 ? 107.688 63.569  121.987 1.00 127.65 ? 328 PRO A O   1 
ATOM 1223 C CB  . PRO A 1 296 ? 107.473 62.761  118.923 1.00 127.89 ? 328 PRO A CB  1 
ATOM 1224 C CG  . PRO A 1 296 ? 108.446 63.847  118.587 1.00 127.20 ? 328 PRO A CG  1 
ATOM 1225 C CD  . PRO A 1 296 ? 107.670 65.123  118.656 1.00 126.75 ? 328 PRO A CD  1 
ATOM 1226 N N   . GLY A 1 297 ? 106.052 62.026  121.843 1.00 124.99 ? 329 GLY A N   1 
ATOM 1227 C CA  . GLY A 1 297 ? 106.208 61.576  123.210 1.00 125.05 ? 329 GLY A CA  1 
ATOM 1228 C C   . GLY A 1 297 ? 105.392 62.330  124.233 1.00 123.39 ? 329 GLY A C   1 
ATOM 1229 O O   . GLY A 1 297 ? 105.705 62.257  125.427 1.00 122.19 ? 329 GLY A O   1 
ATOM 1230 N N   . GLU A 1 298 ? 104.358 63.052  123.811 1.00 108.21 ? 330 GLU A N   1 
ATOM 1231 C CA  . GLU A 1 298 ? 103.507 63.817  124.710 1.00 105.94 ? 330 GLU A CA  1 
ATOM 1232 C C   . GLU A 1 298 ? 102.106 63.225  124.699 1.00 106.89 ? 330 GLU A C   1 
ATOM 1233 O O   . GLU A 1 298 ? 101.535 62.991  123.629 1.00 106.86 ? 330 GLU A O   1 
ATOM 1234 C CB  . GLU A 1 298 ? 103.463 65.293  124.307 1.00 104.80 ? 330 GLU A CB  1 
ATOM 1235 N N   . ASP A 1 299 ? 101.559 62.988  125.887 1.00 101.21 ? 331 ASP A N   1 
ATOM 1236 C CA  . ASP A 1 299 ? 100.229 62.417  125.998 1.00 98.12  ? 331 ASP A CA  1 
ATOM 1237 C C   . ASP A 1 299 ? 99.183  63.418  125.510 1.00 97.60  ? 331 ASP A C   1 
ATOM 1238 O O   . ASP A 1 299 ? 99.421  64.628  125.518 1.00 101.29 ? 331 ASP A O   1 
ATOM 1239 C CB  . ASP A 1 299 ? 99.939  62.021  127.444 1.00 98.05  ? 331 ASP A CB  1 
ATOM 1240 N N   . PRO A 1 300 ? 98.022  62.940  125.056 1.00 100.80 ? 332 PRO A N   1 
ATOM 1241 C CA  . PRO A 1 300 ? 96.964  63.881  124.659 1.00 102.55 ? 332 PRO A CA  1 
ATOM 1242 C C   . PRO A 1 300 ? 96.481  64.756  125.799 1.00 104.30 ? 332 PRO A C   1 
ATOM 1243 O O   . PRO A 1 300 ? 96.029  65.882  125.556 1.00 102.61 ? 332 PRO A O   1 
ATOM 1244 C CB  . PRO A 1 300 ? 95.854  62.960  124.136 1.00 103.16 ? 332 PRO A CB  1 
ATOM 1245 C CG  . PRO A 1 300 ? 96.089  61.660  124.820 1.00 104.37 ? 332 PRO A CG  1 
ATOM 1246 C CD  . PRO A 1 300 ? 97.579  61.538  124.960 1.00 102.63 ? 332 PRO A CD  1 
ATOM 1247 N N   . ARG A 1 301 ? 96.562  64.272  127.040 1.00 106.28 ? 333 ARG A N   1 
ATOM 1248 C CA  . ARG A 1 301 ? 96.078  65.052  128.174 1.00 104.44 ? 333 ARG A CA  1 
ATOM 1249 C C   . ARG A 1 301 ? 96.899  66.321  128.372 1.00 104.53 ? 333 ARG A C   1 
ATOM 1250 O O   . ARG A 1 301 ? 96.340  67.398  128.607 1.00 105.91 ? 333 ARG A O   1 
ATOM 1251 C CB  . ARG A 1 301 ? 96.094  64.196  129.439 1.00 104.29 ? 333 ARG A CB  1 
ATOM 1252 C CG  . ARG A 1 301 ? 95.115  63.038  129.404 1.00 105.03 ? 333 ARG A CG  1 
ATOM 1253 C CD  . ARG A 1 301 ? 94.599  62.704  130.798 1.00 107.07 ? 333 ARG A CD  1 
ATOM 1254 N NE  . ARG A 1 301 ? 95.543  61.911  131.578 1.00 108.86 ? 333 ARG A NE  1 
ATOM 1255 C CZ  . ARG A 1 301 ? 95.961  60.692  131.260 1.00 110.08 ? 333 ARG A CZ  1 
ATOM 1256 N NH1 . ARG A 1 301 ? 95.501  60.055  130.195 1.00 108.96 ? 333 ARG A NH1 1 
ATOM 1257 N NH2 . ARG A 1 301 ? 96.853  60.089  132.041 1.00 108.98 ? 333 ARG A NH2 1 
ATOM 1258 N N   . VAL A 1 302 ? 98.227  66.218  128.280 1.00 90.09  ? 334 VAL A N   1 
ATOM 1259 C CA  . VAL A 1 302 ? 99.078  67.383  128.492 1.00 89.19  ? 334 VAL A CA  1 
ATOM 1260 C C   . VAL A 1 302 ? 99.007  68.362  127.332 1.00 89.97  ? 334 VAL A C   1 
ATOM 1261 O O   . VAL A 1 302 ? 99.378  69.529  127.489 1.00 91.49  ? 334 VAL A O   1 
ATOM 1262 C CB  . VAL A 1 302 ? 100.533 66.939  128.752 1.00 93.31  ? 334 VAL A CB  1 
ATOM 1263 C CG1 . VAL A 1 302 ? 101.134 66.293  127.517 1.00 92.85  ? 334 VAL A CG1 1 
ATOM 1264 C CG2 . VAL A 1 302 ? 101.391 68.098  129.253 1.00 92.59  ? 334 VAL A CG2 1 
ATOM 1265 N N   . THR A 1 303 ? 98.518  67.925  126.175 1.00 91.46  ? 335 THR A N   1 
ATOM 1266 C CA  . THR A 1 303 ? 98.298  68.805  125.037 1.00 92.87  ? 335 THR A CA  1 
ATOM 1267 C C   . THR A 1 303 ? 97.037  69.647  125.190 1.00 90.78  ? 335 THR A C   1 
ATOM 1268 O O   . THR A 1 303 ? 96.977  70.758  124.656 1.00 93.99  ? 335 THR A O   1 
ATOM 1269 C CB  . THR A 1 303 ? 98.229  67.976  123.747 1.00 96.96  ? 335 THR A CB  1 
ATOM 1270 O OG1 . THR A 1 303 ? 99.463  67.268  123.571 1.00 98.63  ? 335 THR A OG1 1 
ATOM 1271 C CG2 . THR A 1 303 ? 98.003  68.863  122.530 1.00 95.57  ? 335 THR A CG2 1 
ATOM 1272 N N   . ARG A 1 304 ? 96.051  69.168  125.944 1.00 85.41  ? 336 ARG A N   1 
ATOM 1273 C CA  . ARG A 1 304 ? 94.792  69.878  126.133 1.00 85.72  ? 336 ARG A CA  1 
ATOM 1274 C C   . ARG A 1 304 ? 94.847  70.905  127.254 1.00 85.67  ? 336 ARG A C   1 
ATOM 1275 O O   . ARG A 1 304 ? 94.395  72.038  127.070 1.00 90.71  ? 336 ARG A O   1 
ATOM 1276 C CB  . ARG A 1 304 ? 93.665  68.881  126.419 1.00 86.83  ? 336 ARG A CB  1 
ATOM 1277 C CG  . ARG A 1 304 ? 92.294  69.515  126.539 1.00 88.41  ? 336 ARG A CG  1 
ATOM 1278 C CD  . ARG A 1 304 ? 91.206  68.463  126.608 1.00 85.94  ? 336 ARG A CD  1 
ATOM 1279 N NE  . ARG A 1 304 ? 90.162  68.823  127.558 1.00 88.04  ? 336 ARG A NE  1 
ATOM 1280 C CZ  . ARG A 1 304 ? 89.711  68.023  128.514 1.00 85.97  ? 336 ARG A CZ  1 
ATOM 1281 N NH1 . ARG A 1 304 ? 90.197  66.804  128.680 1.00 86.20  ? 336 ARG A NH1 1 
ATOM 1282 N NH2 . ARG A 1 304 ? 88.750  68.457  129.324 1.00 83.56  ? 336 ARG A NH2 1 
ATOM 1283 N N   . ALA A 1 305 ? 95.402  70.542  128.411 1.00 74.11  ? 337 ALA A N   1 
ATOM 1284 C CA  . ALA A 1 305 ? 95.507  71.445  129.550 1.00 77.48  ? 337 ALA A CA  1 
ATOM 1285 C C   . ALA A 1 305 ? 96.645  72.441  129.397 1.00 82.52  ? 337 ALA A C   1 
ATOM 1286 O O   . ALA A 1 305 ? 97.017  73.114  130.366 1.00 90.02  ? 337 ALA A O   1 
ATOM 1287 C CB  . ALA A 1 305 ? 95.670  70.644  130.842 1.00 81.36  ? 337 ALA A CB  1 
ATOM 1288 N N   . LYS A 1 306 ? 97.207  72.547  128.200 1.00 74.36  ? 338 LYS A N   1 
ATOM 1289 C CA  . LYS A 1 306 ? 98.297  73.466  127.918 1.00 78.26  ? 338 LYS A CA  1 
ATOM 1290 C C   . LYS A 1 306 ? 97.920  74.568  126.947 1.00 79.88  ? 338 LYS A C   1 
ATOM 1291 O O   . LYS A 1 306 ? 98.474  75.668  127.052 1.00 87.98  ? 338 LYS A O   1 
ATOM 1292 C CB  . LYS A 1 306 ? 99.501  72.694  127.358 1.00 81.04  ? 338 LYS A CB  1 
ATOM 1293 C CG  . LYS A 1 306 ? 100.747 73.513  127.122 1.00 79.33  ? 338 LYS A CG  1 
ATOM 1294 C CD  . LYS A 1 306 ? 101.383 73.139  125.800 1.00 75.75  ? 338 LYS A CD  1 
ATOM 1295 C CE  . LYS A 1 306 ? 102.173 71.852  125.911 1.00 79.07  ? 338 LYS A CE  1 
ATOM 1296 N NZ  . LYS A 1 306 ? 103.207 71.759  124.847 1.00 77.21  ? 338 LYS A NZ  1 
ATOM 1297 N N   . TYR A 1 307 ? 96.997  74.323  126.021 1.00 66.50  ? 339 TYR A N   1 
ATOM 1298 C CA  . TYR A 1 307 ? 96.508  75.353  125.120 1.00 70.39  ? 339 TYR A CA  1 
ATOM 1299 C C   . TYR A 1 307 ? 95.353  76.151  125.705 1.00 76.32  ? 339 TYR A C   1 
ATOM 1300 O O   . TYR A 1 307 ? 95.010  77.204  125.158 1.00 80.28  ? 339 TYR A O   1 
ATOM 1301 C CB  . TYR A 1 307 ? 96.078  74.726  123.792 1.00 71.87  ? 339 TYR A CB  1 
ATOM 1302 C CG  . TYR A 1 307 ? 97.217  74.521  122.827 1.00 72.58  ? 339 TYR A CG  1 
ATOM 1303 C CD1 . TYR A 1 307 ? 97.694  75.568  122.057 1.00 70.90  ? 339 TYR A CD1 1 
ATOM 1304 C CD2 . TYR A 1 307 ? 97.824  73.284  122.694 1.00 74.64  ? 339 TYR A CD2 1 
ATOM 1305 C CE1 . TYR A 1 307 ? 98.735  75.388  121.177 1.00 70.22  ? 339 TYR A CE1 1 
ATOM 1306 C CE2 . TYR A 1 307 ? 98.867  73.095  121.818 1.00 75.03  ? 339 TYR A CE2 1 
ATOM 1307 C CZ  . TYR A 1 307 ? 99.319  74.150  121.062 1.00 75.68  ? 339 TYR A CZ  1 
ATOM 1308 O OH  . TYR A 1 307 ? 100.360 73.969  120.184 1.00 81.44  ? 339 TYR A OH  1 
ATOM 1309 N N   . PHE A 1 308 ? 94.753  75.684  126.800 1.00 73.80  ? 340 PHE A N   1 
ATOM 1310 C CA  . PHE A 1 308 ? 93.696  76.436  127.466 1.00 67.57  ? 340 PHE A CA  1 
ATOM 1311 C C   . PHE A 1 308 ? 94.225  77.735  128.061 1.00 67.83  ? 340 PHE A C   1 
ATOM 1312 O O   . PHE A 1 308 ? 93.566  78.779  127.978 1.00 76.31  ? 340 PHE A O   1 
ATOM 1313 C CB  . PHE A 1 308 ? 93.055  75.573  128.550 1.00 63.65  ? 340 PHE A CB  1 
ATOM 1314 C CG  . PHE A 1 308 ? 91.896  76.220  129.235 1.00 60.24  ? 340 PHE A CG  1 
ATOM 1315 C CD1 . PHE A 1 308 ? 90.892  76.824  128.504 1.00 71.86  ? 340 PHE A CD1 1 
ATOM 1316 C CD2 . PHE A 1 308 ? 91.805  76.220  130.610 1.00 65.51  ? 340 PHE A CD2 1 
ATOM 1317 C CE1 . PHE A 1 308 ? 89.823  77.420  129.134 1.00 76.95  ? 340 PHE A CE1 1 
ATOM 1318 C CE2 . PHE A 1 308 ? 90.743  76.814  131.246 1.00 68.75  ? 340 PHE A CE2 1 
ATOM 1319 C CZ  . PHE A 1 308 ? 89.748  77.415  130.508 1.00 73.47  ? 340 PHE A CZ  1 
ATOM 1320 N N   . ILE A 1 309 ? 95.413  77.687  128.662 1.00 55.73  ? 341 ILE A N   1 
ATOM 1321 C CA  . ILE A 1 309 ? 95.994  78.883  129.260 1.00 60.61  ? 341 ILE A CA  1 
ATOM 1322 C C   . ILE A 1 309 ? 96.344  79.904  128.184 1.00 64.31  ? 341 ILE A C   1 
ATOM 1323 O O   . ILE A 1 309 ? 96.070  81.107  128.329 1.00 77.17  ? 341 ILE A O   1 
ATOM 1324 C CB  . ILE A 1 309 ? 97.215  78.496  130.112 1.00 60.04  ? 341 ILE A CB  1 
ATOM 1325 C CG1 . ILE A 1 309 ? 96.771  77.572  131.244 1.00 61.86  ? 341 ILE A CG1 1 
ATOM 1326 C CG2 . ILE A 1 309 ? 97.888  79.729  130.672 1.00 66.86  ? 341 ILE A CG2 1 
ATOM 1327 C CD1 . ILE A 1 309 ? 97.890  76.852  131.926 1.00 65.33  ? 341 ILE A CD1 1 
ATOM 1328 N N   . ARG A 1 310 ? 96.944  79.444  127.085 1.00 58.70  ? 342 ARG A N   1 
ATOM 1329 C CA  . ARG A 1 310 ? 97.215  80.343  125.971 1.00 62.07  ? 342 ARG A CA  1 
ATOM 1330 C C   . ARG A 1 310 ? 95.922  80.892  125.395 1.00 65.74  ? 342 ARG A C   1 
ATOM 1331 O O   . ARG A 1 310 ? 95.867  82.050  124.969 1.00 72.10  ? 342 ARG A O   1 
ATOM 1332 C CB  . ARG A 1 310 ? 98.024  79.627  124.892 1.00 68.02  ? 342 ARG A CB  1 
ATOM 1333 C CG  . ARG A 1 310 ? 98.473  80.533  123.756 1.00 68.98  ? 342 ARG A CG  1 
ATOM 1334 C CD  . ARG A 1 310 ? 99.314  79.775  122.741 1.00 73.84  ? 342 ARG A CD  1 
ATOM 1335 N NE  . ARG A 1 310 ? 98.528  78.846  121.940 1.00 74.19  ? 342 ARG A NE  1 
ATOM 1336 C CZ  . ARG A 1 310 ? 97.894  79.170  120.822 1.00 73.90  ? 342 ARG A CZ  1 
ATOM 1337 N NH1 . ARG A 1 310 ? 97.954  80.393  120.323 1.00 73.61  ? 342 ARG A NH1 1 
ATOM 1338 N NH2 . ARG A 1 310 ? 97.190  78.241  120.183 1.00 72.43  ? 342 ARG A NH2 1 
ATOM 1339 N N   . ASP A 1 311 ? 94.866  80.076  125.379 1.00 71.58  ? 343 ASP A N   1 
ATOM 1340 C CA  . ASP A 1 311 ? 93.575  80.554  124.903 1.00 73.97  ? 343 ASP A CA  1 
ATOM 1341 C C   . ASP A 1 311 ? 93.053  81.684  125.777 1.00 76.82  ? 343 ASP A C   1 
ATOM 1342 O O   . ASP A 1 311 ? 92.552  82.689  125.265 1.00 79.55  ? 343 ASP A O   1 
ATOM 1343 C CB  . ASP A 1 311 ? 92.573  79.402  124.858 1.00 73.70  ? 343 ASP A CB  1 
ATOM 1344 N N   . GLU A 1 312 ? 93.170  81.542  127.098 1.00 69.38  ? 344 GLU A N   1 
ATOM 1345 C CA  . GLU A 1 312 ? 92.710  82.599  127.998 1.00 64.16  ? 344 GLU A CA  1 
ATOM 1346 C C   . GLU A 1 312 ? 93.501  83.884  127.784 1.00 64.92  ? 344 GLU A C   1 
ATOM 1347 O O   . GLU A 1 312 ? 92.924  84.976  127.657 1.00 70.46  ? 344 GLU A O   1 
ATOM 1348 C CB  . GLU A 1 312 ? 92.822  82.140  129.450 1.00 56.56  ? 344 GLU A CB  1 
ATOM 1349 C CG  . GLU A 1 312 ? 91.794  81.106  129.854 1.00 67.92  ? 344 GLU A CG  1 
ATOM 1350 C CD  . GLU A 1 312 ? 90.530  81.728  130.404 1.00 76.56  ? 344 GLU A CD  1 
ATOM 1351 O OE1 . GLU A 1 312 ? 90.633  82.625  131.266 1.00 76.32  ? 344 GLU A OE1 1 
ATOM 1352 O OE2 . GLU A 1 312 ? 89.431  81.316  129.978 1.00 77.78  ? 344 GLU A OE2 1 
ATOM 1353 N N   . PHE A 1 313 ? 94.829  83.771  127.725 1.00 52.55  ? 345 PHE A N   1 
ATOM 1354 C CA  . PHE A 1 313 ? 95.655  84.962  127.555 1.00 53.39  ? 345 PHE A CA  1 
ATOM 1355 C C   . PHE A 1 313 ? 95.383  85.642  126.216 1.00 60.28  ? 345 PHE A C   1 
ATOM 1356 O O   . PHE A 1 313 ? 95.258  86.872  126.146 1.00 63.09  ? 345 PHE A O   1 
ATOM 1357 C CB  . PHE A 1 313 ? 97.131  84.598  127.690 1.00 59.15  ? 345 PHE A CB  1 
ATOM 1358 C CG  . PHE A 1 313 ? 97.614  84.538  129.111 1.00 57.95  ? 345 PHE A CG  1 
ATOM 1359 C CD1 . PHE A 1 313 ? 98.128  85.658  129.729 1.00 58.00  ? 345 PHE A CD1 1 
ATOM 1360 C CD2 . PHE A 1 313 ? 97.558  83.358  129.826 1.00 61.66  ? 345 PHE A CD2 1 
ATOM 1361 C CE1 . PHE A 1 313 ? 98.575  85.600  131.030 1.00 57.95  ? 345 PHE A CE1 1 
ATOM 1362 C CE2 . PHE A 1 313 ? 98.004  83.297  131.128 1.00 55.91  ? 345 PHE A CE2 1 
ATOM 1363 C CZ  . PHE A 1 313 ? 98.511  84.418  131.728 1.00 56.29  ? 345 PHE A CZ  1 
ATOM 1364 N N   . LEU A 1 314 ? 95.256  84.861  125.141 1.00 64.50  ? 346 LEU A N   1 
ATOM 1365 C CA  . LEU A 1 314 ? 95.011  85.455  123.833 1.00 64.06  ? 346 LEU A CA  1 
ATOM 1366 C C   . LEU A 1 314 ? 93.594  85.997  123.712 1.00 64.85  ? 346 LEU A C   1 
ATOM 1367 O O   . LEU A 1 314 ? 93.361  86.941  122.951 1.00 67.65  ? 346 LEU A O   1 
ATOM 1368 C CB  . LEU A 1 314 ? 95.285  84.435  122.730 1.00 68.45  ? 346 LEU A CB  1 
ATOM 1369 C CG  . LEU A 1 314 ? 96.750  84.245  122.343 1.00 72.02  ? 346 LEU A CG  1 
ATOM 1370 C CD1 . LEU A 1 314 ? 96.860  83.384  121.100 1.00 69.96  ? 346 LEU A CD1 1 
ATOM 1371 C CD2 . LEU A 1 314 ? 97.427  85.586  122.127 1.00 68.83  ? 346 LEU A CD2 1 
ATOM 1372 N N   . ARG A 1 315 ? 92.635  85.419  124.436 1.00 63.45  ? 347 ARG A N   1 
ATOM 1373 C CA  . ARG A 1 315 ? 91.294  85.986  124.464 1.00 61.03  ? 347 ARG A CA  1 
ATOM 1374 C C   . ARG A 1 315 ? 91.293  87.338  125.159 1.00 67.95  ? 347 ARG A C   1 
ATOM 1375 O O   . ARG A 1 315 ? 90.586  88.259  124.736 1.00 70.84  ? 347 ARG A O   1 
ATOM 1376 C CB  . ARG A 1 315 ? 90.331  85.022  125.152 1.00 64.22  ? 347 ARG A CB  1 
ATOM 1377 C CG  . ARG A 1 315 ? 88.892  85.486  125.154 1.00 66.04  ? 347 ARG A CG  1 
ATOM 1378 C CD  . ARG A 1 315 ? 88.225  85.188  126.482 1.00 69.30  ? 347 ARG A CD  1 
ATOM 1379 N NE  . ARG A 1 315 ? 88.222  83.760  126.776 1.00 72.02  ? 347 ARG A NE  1 
ATOM 1380 C CZ  . ARG A 1 315 ? 88.053  83.246  127.986 1.00 73.07  ? 347 ARG A CZ  1 
ATOM 1381 N NH1 . ARG A 1 315 ? 87.874  84.017  129.046 1.00 72.11  ? 347 ARG A NH1 1 
ATOM 1382 N NH2 . ARG A 1 315 ? 88.064  81.925  128.136 1.00 71.96  ? 347 ARG A NH2 1 
ATOM 1383 N N   . ILE A 1 316 ? 92.077  87.476  126.230 1.00 69.02  ? 348 ILE A N   1 
ATOM 1384 C CA  . ILE A 1 316 ? 92.240  88.792  126.846 1.00 55.69  ? 348 ILE A CA  1 
ATOM 1385 C C   . ILE A 1 316 ? 92.912  89.750  125.870 1.00 49.90  ? 348 ILE A C   1 
ATOM 1386 O O   . ILE A 1 316 ? 92.559  90.932  125.791 1.00 53.65  ? 348 ILE A O   1 
ATOM 1387 C CB  . ILE A 1 316 ? 93.023  88.676  128.167 1.00 57.09  ? 348 ILE A CB  1 
ATOM 1388 C CG1 . ILE A 1 316 ? 92.089  88.260  129.301 1.00 63.52  ? 348 ILE A CG1 1 
ATOM 1389 C CG2 . ILE A 1 316 ? 93.689  89.985  128.515 1.00 52.40  ? 348 ILE A CG2 1 
ATOM 1390 C CD1 . ILE A 1 316 ? 92.800  87.990  130.605 1.00 62.18  ? 348 ILE A CD1 1 
ATOM 1391 N N   . SER A 1 317 ? 93.884  89.252  125.105 1.00 62.22  ? 349 SER A N   1 
ATOM 1392 C CA  . SER A 1 317 ? 94.597  90.104  124.157 1.00 61.01  ? 349 SER A CA  1 
ATOM 1393 C C   . SER A 1 317 ? 93.690  90.606  123.039 1.00 63.15  ? 349 SER A C   1 
ATOM 1394 O O   . SER A 1 317 ? 93.755  91.783  122.664 1.00 68.32  ? 349 SER A O   1 
ATOM 1395 C CB  . SER A 1 317 ? 95.786  89.348  123.569 1.00 66.31  ? 349 SER A CB  1 
ATOM 1396 O OG  . SER A 1 317 ? 96.472  90.146  122.621 1.00 68.14  ? 349 SER A OG  1 
ATOM 1397 N N   . THR A 1 318 ? 92.842  89.735  122.488 1.00 73.28  ? 350 THR A N   1 
ATOM 1398 C CA  . THR A 1 318 ? 92.069  90.090  121.300 1.00 73.18  ? 350 THR A CA  1 
ATOM 1399 C C   . THR A 1 318 ? 90.769  90.807  121.634 1.00 65.59  ? 350 THR A C   1 
ATOM 1400 O O   . THR A 1 318 ? 90.029  91.186  120.721 1.00 61.71  ? 350 THR A O   1 
ATOM 1401 C CB  . THR A 1 318 ? 91.760  88.844  120.471 1.00 73.32  ? 350 THR A CB  1 
ATOM 1402 O OG1 . THR A 1 318 ? 91.011  87.914  121.263 1.00 76.86  ? 350 THR A OG1 1 
ATOM 1403 C CG2 . THR A 1 318 ? 93.045  88.188  119.990 1.00 71.42  ? 350 THR A CG2 1 
ATOM 1404 N N   . ALA A 1 319 ? 90.463  90.991  122.919 1.00 78.54  ? 351 ALA A N   1 
ATOM 1405 C CA  . ALA A 1 319 ? 89.247  91.709  123.283 1.00 82.04  ? 351 ALA A CA  1 
ATOM 1406 C C   . ALA A 1 319 ? 89.293  93.160  122.826 1.00 80.91  ? 351 ALA A C   1 
ATOM 1407 O O   . ALA A 1 319 ? 88.252  93.740  122.500 1.00 82.43  ? 351 ALA A O   1 
ATOM 1408 C CB  . ALA A 1 319 ? 89.025  91.635  124.794 1.00 79.97  ? 351 ALA A CB  1 
ATOM 1409 N N   . SER A 1 320 ? 90.479  93.760  122.792 1.00 82.39  ? 352 SER A N   1 
ATOM 1410 C CA  . SER A 1 320 ? 90.630  95.154  122.405 1.00 82.65  ? 352 SER A CA  1 
ATOM 1411 C C   . SER A 1 320 ? 92.029  95.347  121.831 1.00 86.21  ? 352 SER A C   1 
ATOM 1412 O O   . SER A 1 320 ? 92.758  94.382  121.586 1.00 89.24  ? 352 SER A O   1 
ATOM 1413 C CB  . SER A 1 320 ? 90.366  96.079  123.599 1.00 83.56  ? 352 SER A CB  1 
ATOM 1414 O OG  . SER A 1 320 ? 91.354  95.911  124.600 1.00 86.19  ? 352 SER A OG  1 
ATOM 1415 N N   . GLY A 1 321 ? 92.403  96.605  121.615 1.00 85.91  ? 353 GLY A N   1 
ATOM 1416 C CA  . GLY A 1 321 ? 93.704  96.958  121.103 1.00 86.83  ? 353 GLY A CA  1 
ATOM 1417 C C   . GLY A 1 321 ? 93.758  97.186  119.607 1.00 90.15  ? 353 GLY A C   1 
ATOM 1418 O O   . GLY A 1 321 ? 94.752  97.735  119.116 1.00 91.23  ? 353 GLY A O   1 
ATOM 1419 N N   . ASP A 1 322 ? 92.720  96.786  118.877 1.00 83.67  ? 354 ASP A N   1 
ATOM 1420 C CA  . ASP A 1 322 ? 92.639  96.947  117.418 1.00 79.24  ? 354 ASP A CA  1 
ATOM 1421 C C   . ASP A 1 322 ? 93.844  96.228  116.814 1.00 79.79  ? 354 ASP A C   1 
ATOM 1422 O O   . ASP A 1 322 ? 94.070  95.051  117.136 1.00 81.53  ? 354 ASP A O   1 
ATOM 1423 C CB  . ASP A 1 322 ? 92.510  98.425  117.075 1.00 80.50  ? 354 ASP A CB  1 
ATOM 1424 N N   . GLY A 1 323 ? 94.633  96.872  115.960 1.00 76.55  ? 355 GLY A N   1 
ATOM 1425 C CA  . GLY A 1 323 ? 95.784  96.226  115.365 1.00 78.31  ? 355 GLY A CA  1 
ATOM 1426 C C   . GLY A 1 323 ? 97.073  96.982  115.602 1.00 80.82  ? 355 GLY A C   1 
ATOM 1427 O O   . GLY A 1 323 ? 98.068  96.761  114.906 1.00 81.14  ? 355 GLY A O   1 
ATOM 1428 N N   . ARG A 1 324 ? 97.064  97.888  116.581 1.00 77.77  ? 356 ARG A N   1 
ATOM 1429 C CA  . ARG A 1 324 ? 98.264  98.661  116.879 1.00 72.44  ? 356 ARG A CA  1 
ATOM 1430 C C   . ARG A 1 324 ? 99.357  97.788  117.485 1.00 77.01  ? 356 ARG A C   1 
ATOM 1431 O O   . ARG A 1 324 ? 100.539 97.964  117.174 1.00 76.89  ? 356 ARG A O   1 
ATOM 1432 C CB  . ARG A 1 324 ? 97.921  99.820  117.813 1.00 69.98  ? 356 ARG A CB  1 
ATOM 1433 N N   . HIS A 1 325 ? 98.988  96.845  118.352 1.00 65.09  ? 357 HIS A N   1 
ATOM 1434 C CA  . HIS A 1 325 ? 99.962  95.996  119.021 1.00 58.77  ? 357 HIS A CA  1 
ATOM 1435 C C   . HIS A 1 325 ? 99.431  94.573  119.125 1.00 61.40  ? 357 HIS A C   1 
ATOM 1436 O O   . HIS A 1 325 ? 98.222  94.336  119.129 1.00 67.99  ? 357 HIS A O   1 
ATOM 1437 C CB  . HIS A 1 325 ? 100.323 96.548  120.406 1.00 59.25  ? 357 HIS A CB  1 
ATOM 1438 C CG  . HIS A 1 325 ? 99.139  96.856  121.267 1.00 61.13  ? 357 HIS A CG  1 
ATOM 1439 N ND1 . HIS A 1 325 ? 98.593  95.940  122.137 1.00 62.70  ? 357 HIS A ND1 1 
ATOM 1440 C CD2 . HIS A 1 325 ? 98.401  97.983  121.397 1.00 65.72  ? 357 HIS A CD2 1 
ATOM 1441 C CE1 . HIS A 1 325 ? 97.569  96.487  122.766 1.00 64.34  ? 357 HIS A CE1 1 
ATOM 1442 N NE2 . HIS A 1 325 ? 97.431  97.727  122.334 1.00 69.74  ? 357 HIS A NE2 1 
ATOM 1443 N N   . TYR A 1 326 ? 100.364 93.625  119.216 1.00 57.51  ? 358 TYR A N   1 
ATOM 1444 C CA  . TYR A 1 326 ? 100.061 92.201  119.177 1.00 54.95  ? 358 TYR A CA  1 
ATOM 1445 C C   . TYR A 1 326 ? 100.773 91.498  120.325 1.00 56.67  ? 358 TYR A C   1 
ATOM 1446 O O   . TYR A 1 326 ? 101.691 92.045  120.939 1.00 66.18  ? 358 TYR A O   1 
ATOM 1447 C CB  . TYR A 1 326 ? 100.480 91.584  117.837 1.00 56.83  ? 358 TYR A CB  1 
ATOM 1448 C CG  . TYR A 1 326 ? 99.905  90.214  117.562 1.00 60.70  ? 358 TYR A CG  1 
ATOM 1449 C CD1 . TYR A 1 326 ? 98.610  89.891  117.938 1.00 64.54  ? 358 TYR A CD1 1 
ATOM 1450 C CD2 . TYR A 1 326 ? 100.665 89.240  116.932 1.00 57.14  ? 358 TYR A CD2 1 
ATOM 1451 C CE1 . TYR A 1 326 ? 98.089  88.636  117.686 1.00 65.74  ? 358 TYR A CE1 1 
ATOM 1452 C CE2 . TYR A 1 326 ? 100.154 87.988  116.679 1.00 51.54  ? 358 TYR A CE2 1 
ATOM 1453 C CZ  . TYR A 1 326 ? 98.867  87.690  117.056 1.00 60.57  ? 358 TYR A CZ  1 
ATOM 1454 O OH  . TYR A 1 326 ? 98.357  86.439  116.803 1.00 66.74  ? 358 TYR A OH  1 
ATOM 1455 N N   . CYS A 1 327 ? 100.335 90.273  120.611 1.00 51.29  ? 359 CYS A N   1 
ATOM 1456 C CA  . CYS A 1 327 ? 100.916 89.439  121.655 1.00 46.72  ? 359 CYS A CA  1 
ATOM 1457 C C   . CYS A 1 327 ? 101.472 88.161  121.041 1.00 63.60  ? 359 CYS A C   1 
ATOM 1458 O O   . CYS A 1 327 ? 100.781 87.488  120.270 1.00 73.63  ? 359 CYS A O   1 
ATOM 1459 C CB  . CYS A 1 327 ? 99.877  89.101  122.723 1.00 49.62  ? 359 CYS A CB  1 
ATOM 1460 S SG  . CYS A 1 327 ? 100.398 87.860  123.914 1.00 71.38  ? 359 CYS A SG  1 
ATOM 1461 N N   . TYR A 1 328 ? 102.719 87.830  121.385 1.00 52.80  ? 360 TYR A N   1 
ATOM 1462 C CA  . TYR A 1 328 ? 103.399 86.647  120.868 1.00 37.34  ? 360 TYR A CA  1 
ATOM 1463 C C   . TYR A 1 328 ? 103.488 85.589  121.956 1.00 47.29  ? 360 TYR A C   1 
ATOM 1464 O O   . TYR A 1 328 ? 104.154 85.823  122.975 1.00 64.58  ? 360 TYR A O   1 
ATOM 1465 C CB  . TYR A 1 328 ? 104.800 87.000  120.374 1.00 42.79  ? 360 TYR A CB  1 
ATOM 1466 C CG  . TYR A 1 328 ? 104.863 88.014  119.260 1.00 45.65  ? 360 TYR A CG  1 
ATOM 1467 C CD1 . TYR A 1 328 ? 104.811 87.621  117.937 1.00 45.02  ? 360 TYR A CD1 1 
ATOM 1468 C CD2 . TYR A 1 328 ? 105.010 89.363  119.534 1.00 50.68  ? 360 TYR A CD2 1 
ATOM 1469 C CE1 . TYR A 1 328 ? 104.882 88.542  116.920 1.00 46.46  ? 360 TYR A CE1 1 
ATOM 1470 C CE2 . TYR A 1 328 ? 105.079 90.290  118.522 1.00 47.77  ? 360 TYR A CE2 1 
ATOM 1471 C CZ  . TYR A 1 328 ? 105.018 89.873  117.218 1.00 45.60  ? 360 TYR A CZ  1 
ATOM 1472 O OH  . TYR A 1 328 ? 105.086 90.796  116.206 1.00 50.63  ? 360 TYR A OH  1 
ATOM 1473 N N   . PRO A 1 329 ? 102.860 84.429  121.799 1.00 40.83  ? 361 PRO A N   1 
ATOM 1474 C CA  . PRO A 1 329 ? 102.980 83.371  122.805 1.00 43.29  ? 361 PRO A CA  1 
ATOM 1475 C C   . PRO A 1 329 ? 104.102 82.391  122.505 1.00 58.20  ? 361 PRO A C   1 
ATOM 1476 O O   . PRO A 1 329 ? 104.461 82.135  121.354 1.00 66.99  ? 361 PRO A O   1 
ATOM 1477 C CB  . PRO A 1 329 ? 101.615 82.669  122.732 1.00 46.45  ? 361 PRO A CB  1 
ATOM 1478 C CG  . PRO A 1 329 ? 100.945 83.182  121.471 1.00 51.20  ? 361 PRO A CG  1 
ATOM 1479 C CD  . PRO A 1 329 ? 101.902 84.069  120.748 1.00 50.07  ? 361 PRO A CD  1 
ATOM 1480 N N   . HIS A 1 330 ? 104.658 81.834  123.580 1.00 57.44  ? 362 HIS A N   1 
ATOM 1481 C CA  . HIS A 1 330 ? 105.715 80.838  123.482 1.00 46.87  ? 362 HIS A CA  1 
ATOM 1482 C C   . HIS A 1 330 ? 105.609 79.890  124.666 1.00 52.14  ? 362 HIS A C   1 
ATOM 1483 O O   . HIS A 1 330 ? 105.000 80.210  125.690 1.00 64.56  ? 362 HIS A O   1 
ATOM 1484 C CB  . HIS A 1 330 ? 107.103 81.482  123.455 1.00 43.15  ? 362 HIS A CB  1 
ATOM 1485 C CG  . HIS A 1 330 ? 107.408 82.224  122.193 1.00 48.64  ? 362 HIS A CG  1 
ATOM 1486 N ND1 . HIS A 1 330 ? 107.484 81.606  120.964 1.00 57.03  ? 362 HIS A ND1 1 
ATOM 1487 C CD2 . HIS A 1 330 ? 107.677 83.531  121.973 1.00 54.88  ? 362 HIS A CD2 1 
ATOM 1488 C CE1 . HIS A 1 330 ? 107.777 82.503  120.040 1.00 60.10  ? 362 HIS A CE1 1 
ATOM 1489 N NE2 . HIS A 1 330 ? 107.900 83.680  120.626 1.00 60.55  ? 362 HIS A NE2 1 
ATOM 1490 N N   . PHE A 1 331 ? 106.207 78.712  124.516 1.00 60.43  ? 363 PHE A N   1 
ATOM 1491 C CA  . PHE A 1 331 ? 106.320 77.738  125.593 1.00 63.52  ? 363 PHE A CA  1 
ATOM 1492 C C   . PHE A 1 331 ? 107.791 77.559  125.939 1.00 72.81  ? 363 PHE A C   1 
ATOM 1493 O O   . PHE A 1 331 ? 108.616 77.321  125.049 1.00 78.28  ? 363 PHE A O   1 
ATOM 1494 C CB  . PHE A 1 331 ? 105.698 76.399  125.198 1.00 66.49  ? 363 PHE A CB  1 
ATOM 1495 C CG  . PHE A 1 331 ? 104.206 76.440  125.067 1.00 65.02  ? 363 PHE A CG  1 
ATOM 1496 C CD1 . PHE A 1 331 ? 103.404 76.556  126.186 1.00 70.17  ? 363 PHE A CD1 1 
ATOM 1497 C CD2 . PHE A 1 331 ? 103.604 76.353  123.827 1.00 66.13  ? 363 PHE A CD2 1 
ATOM 1498 C CE1 . PHE A 1 331 ? 102.031 76.597  126.069 1.00 70.87  ? 363 PHE A CE1 1 
ATOM 1499 C CE2 . PHE A 1 331 ? 102.232 76.391  123.705 1.00 69.33  ? 363 PHE A CE2 1 
ATOM 1500 C CZ  . PHE A 1 331 ? 101.445 76.513  124.828 1.00 68.46  ? 363 PHE A CZ  1 
ATOM 1501 N N   . THR A 1 332 ? 108.119 77.671  127.224 1.00 74.25  ? 364 THR A N   1 
ATOM 1502 C CA  . THR A 1 332 ? 109.505 77.732  127.661 1.00 77.71  ? 364 THR A CA  1 
ATOM 1503 C C   . THR A 1 332 ? 109.685 76.935  128.943 1.00 80.23  ? 364 THR A C   1 
ATOM 1504 O O   . THR A 1 332 ? 108.825 76.967  129.827 1.00 83.30  ? 364 THR A O   1 
ATOM 1505 C CB  . THR A 1 332 ? 109.944 79.188  127.882 1.00 77.55  ? 364 THR A CB  1 
ATOM 1506 O OG1 . THR A 1 332 ? 109.815 79.918  126.657 1.00 80.35  ? 364 THR A OG1 1 
ATOM 1507 C CG2 . THR A 1 332 ? 111.389 79.260  128.352 1.00 78.33  ? 364 THR A CG2 1 
ATOM 1508 N N   . CYS A 1 333 ? 110.802 76.222  129.035 1.00 88.91  ? 365 CYS A N   1 
ATOM 1509 C CA  . CYS A 1 333 ? 111.186 75.504  130.240 1.00 88.35  ? 365 CYS A CA  1 
ATOM 1510 C C   . CYS A 1 333 ? 112.260 76.278  130.994 1.00 89.79  ? 365 CYS A C   1 
ATOM 1511 O O   . CYS A 1 333 ? 112.834 77.245  130.488 1.00 90.99  ? 365 CYS A O   1 
ATOM 1512 C CB  . CYS A 1 333 ? 111.690 74.100  129.901 1.00 89.05  ? 365 CYS A CB  1 
ATOM 1513 S SG  . CYS A 1 333 ? 111.526 72.910  131.247 1.00 97.71  ? 365 CYS A SG  1 
ATOM 1514 N N   . SER A 1 334 ? 112.523 75.840  132.226 1.00 92.81  ? 366 SER A N   1 
ATOM 1515 C CA  . SER A 1 334 ? 113.497 76.529  133.067 1.00 92.55  ? 366 SER A CA  1 
ATOM 1516 C C   . SER A 1 334 ? 114.897 76.443  132.475 1.00 96.40  ? 366 SER A C   1 
ATOM 1517 O O   . SER A 1 334 ? 115.578 77.463  132.316 1.00 95.79  ? 366 SER A O   1 
ATOM 1518 C CB  . SER A 1 334 ? 113.478 75.943  134.477 1.00 94.66  ? 366 SER A CB  1 
ATOM 1519 O OG  . SER A 1 334 ? 114.327 74.813  134.564 1.00 93.58  ? 366 SER A OG  1 
ATOM 1520 N N   . VAL A 1 335 ? 115.343 75.237  132.137 1.00 101.60 ? 367 VAL A N   1 
ATOM 1521 C CA  . VAL A 1 335 ? 116.668 75.016  131.571 1.00 100.96 ? 367 VAL A CA  1 
ATOM 1522 C C   . VAL A 1 335 ? 116.496 74.757  130.076 1.00 99.93  ? 367 VAL A C   1 
ATOM 1523 O O   . VAL A 1 335 ? 115.955 73.730  129.655 1.00 100.27 ? 367 VAL A O   1 
ATOM 1524 C CB  . VAL A 1 335 ? 117.414 73.886  132.292 1.00 99.85  ? 367 VAL A CB  1 
ATOM 1525 C CG1 . VAL A 1 335 ? 116.641 72.568  132.250 1.00 98.31  ? 367 VAL A CG1 1 
ATOM 1526 C CG2 . VAL A 1 335 ? 118.805 73.711  131.699 1.00 99.13  ? 367 VAL A CG2 1 
ATOM 1527 N N   . ASP A 1 336 ? 116.936 75.717  129.269 1.00 90.54  ? 368 ASP A N   1 
ATOM 1528 C CA  . ASP A 1 336 ? 116.902 75.631  127.816 1.00 91.53  ? 368 ASP A CA  1 
ATOM 1529 C C   . ASP A 1 336 ? 117.657 76.824  127.259 1.00 93.05  ? 368 ASP A C   1 
ATOM 1530 O O   . ASP A 1 336 ? 117.701 77.886  127.885 1.00 94.69  ? 368 ASP A O   1 
ATOM 1531 C CB  . ASP A 1 336 ? 115.465 75.617  127.279 1.00 90.61  ? 368 ASP A CB  1 
ATOM 1532 N N   . THR A 1 337 ? 118.247 76.646  126.080 1.00 88.76  ? 369 THR A N   1 
ATOM 1533 C CA  . THR A 1 337 ? 118.909 77.747  125.384 1.00 88.56  ? 369 THR A CA  1 
ATOM 1534 C C   . THR A 1 337 ? 118.223 77.918  124.035 1.00 86.37  ? 369 THR A C   1 
ATOM 1535 O O   . THR A 1 337 ? 118.721 77.475  122.999 1.00 91.81  ? 369 THR A O   1 
ATOM 1536 C CB  . THR A 1 337 ? 120.406 77.481  125.228 1.00 91.91  ? 369 THR A CB  1 
ATOM 1537 O OG1 . THR A 1 337 ? 120.604 76.297  124.446 1.00 92.94  ? 369 THR A OG1 1 
ATOM 1538 C CG2 . THR A 1 337 ? 121.061 77.298  126.589 1.00 91.50  ? 369 THR A CG2 1 
ATOM 1539 N N   . GLU A 1 338 ? 117.065 78.569  124.061 1.00 75.11  ? 370 GLU A N   1 
ATOM 1540 C CA  . GLU A 1 338 ? 116.387 79.023  122.857 1.00 78.77  ? 370 GLU A CA  1 
ATOM 1541 C C   . GLU A 1 338 ? 115.744 80.389  123.018 1.00 85.68  ? 370 GLU A C   1 
ATOM 1542 O O   . GLU A 1 338 ? 115.315 80.965  122.014 1.00 88.34  ? 370 GLU A O   1 
ATOM 1543 C CB  . GLU A 1 338 ? 115.317 78.011  122.426 1.00 79.77  ? 370 GLU A CB  1 
ATOM 1544 N N   . ASN A 1 339 ? 115.654 80.922  124.240 1.00 74.82  ? 371 ASN A N   1 
ATOM 1545 C CA  . ASN A 1 339 ? 114.864 82.121  124.485 1.00 71.86  ? 371 ASN A CA  1 
ATOM 1546 C C   . ASN A 1 339 ? 115.454 83.345  123.801 1.00 77.04  ? 371 ASN A C   1 
ATOM 1547 O O   . ASN A 1 339 ? 114.707 84.235  123.376 1.00 83.59  ? 371 ASN A O   1 
ATOM 1548 C CB  . ASN A 1 339 ? 114.738 82.355  125.988 1.00 70.03  ? 371 ASN A CB  1 
ATOM 1549 C CG  . ASN A 1 339 ? 114.147 81.166  126.707 1.00 72.02  ? 371 ASN A CG  1 
ATOM 1550 O OD1 . ASN A 1 339 ? 113.468 80.340  126.103 1.00 73.84  ? 371 ASN A OD1 1 
ATOM 1551 N ND2 . ASN A 1 339 ? 114.407 81.068  128.002 1.00 74.34  ? 371 ASN A ND2 1 
ATOM 1552 N N   . ALA A 1 340 ? 116.781 83.412  123.687 1.00 64.96  ? 372 ALA A N   1 
ATOM 1553 C CA  . ALA A 1 340 ? 117.394 84.514  122.958 1.00 62.96  ? 372 ALA A CA  1 
ATOM 1554 C C   . ALA A 1 340 ? 116.944 84.518  121.505 1.00 65.36  ? 372 ALA A C   1 
ATOM 1555 O O   . ALA A 1 340 ? 116.642 85.577  120.942 1.00 75.59  ? 372 ALA A O   1 
ATOM 1556 C CB  . ALA A 1 340 ? 118.915 84.425  123.055 1.00 63.10  ? 372 ALA A CB  1 
ATOM 1557 N N   . ARG A 1 341 ? 116.876 83.337  120.889 1.00 63.53  ? 373 ARG A N   1 
ATOM 1558 C CA  . ARG A 1 341 ? 116.404 83.236  119.514 1.00 67.50  ? 373 ARG A CA  1 
ATOM 1559 C C   . ARG A 1 341 ? 114.956 83.693  119.390 1.00 75.66  ? 373 ARG A C   1 
ATOM 1560 O O   . ARG A 1 341 ? 114.599 84.403  118.439 1.00 79.50  ? 373 ARG A O   1 
ATOM 1561 C CB  . ARG A 1 341 ? 116.559 81.798  119.024 1.00 66.44  ? 373 ARG A CB  1 
ATOM 1562 C CG  . ARG A 1 341 ? 116.272 81.604  117.553 1.00 73.99  ? 373 ARG A CG  1 
ATOM 1563 C CD  . ARG A 1 341 ? 117.060 82.582  116.714 1.00 73.76  ? 373 ARG A CD  1 
ATOM 1564 N NE  . ARG A 1 341 ? 118.497 82.397  116.866 1.00 74.77  ? 373 ARG A NE  1 
ATOM 1565 C CZ  . ARG A 1 341 ? 119.395 82.811  115.985 1.00 75.51  ? 373 ARG A CZ  1 
ATOM 1566 N NH1 . ARG A 1 341 ? 119.036 83.430  114.872 1.00 69.20  ? 373 ARG A NH1 1 
ATOM 1567 N NH2 . ARG A 1 341 ? 120.685 82.600  116.225 1.00 73.68  ? 373 ARG A NH2 1 
ATOM 1568 N N   . ARG A 1 342 ? 114.106 83.291  120.337 1.00 67.68  ? 374 ARG A N   1 
ATOM 1569 C CA  . ARG A 1 342 ? 112.702 83.683  120.284 1.00 65.06  ? 374 ARG A CA  1 
ATOM 1570 C C   . ARG A 1 342 ? 112.548 85.192  120.421 1.00 69.02  ? 374 ARG A C   1 
ATOM 1571 O O   . ARG A 1 342 ? 111.764 85.816  119.690 1.00 80.02  ? 374 ARG A O   1 
ATOM 1572 C CB  . ARG A 1 342 ? 111.919 82.965  121.380 1.00 61.52  ? 374 ARG A CB  1 
ATOM 1573 C CG  . ARG A 1 342 ? 111.932 81.450  121.275 1.00 66.26  ? 374 ARG A CG  1 
ATOM 1574 C CD  . ARG A 1 342 ? 110.986 80.839  122.291 1.00 67.86  ? 374 ARG A CD  1 
ATOM 1575 N NE  . ARG A 1 342 ? 110.979 79.382  122.252 1.00 70.77  ? 374 ARG A NE  1 
ATOM 1576 C CZ  . ARG A 1 342 ? 111.654 78.610  123.092 1.00 69.19  ? 374 ARG A CZ  1 
ATOM 1577 N NH1 . ARG A 1 342 ? 112.396 79.123  124.058 1.00 65.79  ? 374 ARG A NH1 1 
ATOM 1578 N NH2 . ARG A 1 342 ? 111.578 77.289  122.962 1.00 68.04  ? 374 ARG A NH2 1 
ATOM 1579 N N   . ILE A 1 343 ? 113.292 85.796  121.350 1.00 55.51  ? 375 ILE A N   1 
ATOM 1580 C CA  . ILE A 1 343 ? 113.238 87.243  121.524 1.00 56.48  ? 375 ILE A CA  1 
ATOM 1581 C C   . ILE A 1 343 ? 113.730 87.948  120.268 1.00 63.44  ? 375 ILE A C   1 
ATOM 1582 O O   . ILE A 1 343 ? 113.155 88.956  119.838 1.00 68.43  ? 375 ILE A O   1 
ATOM 1583 C CB  . ILE A 1 343 ? 114.043 87.663  122.766 1.00 54.77  ? 375 ILE A CB  1 
ATOM 1584 C CG1 . ILE A 1 343 ? 113.364 87.155  124.035 1.00 59.32  ? 375 ILE A CG1 1 
ATOM 1585 C CG2 . ILE A 1 343 ? 114.192 89.168  122.822 1.00 61.46  ? 375 ILE A CG2 1 
ATOM 1586 C CD1 . ILE A 1 343 ? 114.209 87.299  125.271 1.00 60.80  ? 375 ILE A CD1 1 
ATOM 1587 N N   . PHE A 1 344 ? 114.795 87.426  119.656 1.00 57.99  ? 376 PHE A N   1 
ATOM 1588 C CA  . PHE A 1 344 ? 115.308 88.010  118.423 1.00 53.51  ? 376 PHE A CA  1 
ATOM 1589 C C   . PHE A 1 344 ? 114.254 87.985  117.325 1.00 63.65  ? 376 PHE A C   1 
ATOM 1590 O O   . PHE A 1 344 ? 114.026 88.991  116.641 1.00 72.99  ? 376 PHE A O   1 
ATOM 1591 C CB  . PHE A 1 344 ? 116.563 87.256  117.986 1.00 57.59  ? 376 PHE A CB  1 
ATOM 1592 C CG  . PHE A 1 344 ? 117.219 87.820  116.765 1.00 59.34  ? 376 PHE A CG  1 
ATOM 1593 C CD1 . PHE A 1 344 ? 117.946 88.989  116.830 1.00 64.98  ? 376 PHE A CD1 1 
ATOM 1594 C CD2 . PHE A 1 344 ? 117.118 87.171  115.553 1.00 57.84  ? 376 PHE A CD2 1 
ATOM 1595 C CE1 . PHE A 1 344 ? 118.551 89.500  115.707 1.00 63.32  ? 376 PHE A CE1 1 
ATOM 1596 C CE2 . PHE A 1 344 ? 117.720 87.681  114.431 1.00 61.96  ? 376 PHE A CE2 1 
ATOM 1597 C CZ  . PHE A 1 344 ? 118.435 88.846  114.507 1.00 59.61  ? 376 PHE A CZ  1 
ATOM 1598 N N   . ASN A 1 345 ? 113.588 86.842  117.156 1.00 56.45  ? 377 ASN A N   1 
ATOM 1599 C CA  . ASN A 1 345 ? 112.575 86.722  116.113 1.00 55.78  ? 377 ASN A CA  1 
ATOM 1600 C C   . ASN A 1 345 ? 111.410 87.676  116.355 1.00 60.57  ? 377 ASN A C   1 
ATOM 1601 O O   . ASN A 1 345 ? 110.952 88.366  115.431 1.00 70.09  ? 377 ASN A O   1 
ATOM 1602 C CB  . ASN A 1 345 ? 112.083 85.280  116.040 1.00 53.90  ? 377 ASN A CB  1 
ATOM 1603 C CG  . ASN A 1 345 ? 113.156 84.326  115.573 1.00 57.42  ? 377 ASN A CG  1 
ATOM 1604 O OD1 . ASN A 1 345 ? 114.167 84.740  115.015 1.00 61.60  ? 377 ASN A OD1 1 
ATOM 1605 N ND2 . ASN A 1 345 ? 112.945 83.039  115.807 1.00 58.95  ? 377 ASN A ND2 1 
ATOM 1606 N N   . ASP A 1 346 ? 110.926 87.738  117.597 1.00 52.99  ? 378 ASP A N   1 
ATOM 1607 C CA  . ASP A 1 346 ? 109.800 88.613  117.902 1.00 51.80  ? 378 ASP A CA  1 
ATOM 1608 C C   . ASP A 1 346 ? 110.162 90.079  117.697 1.00 57.81  ? 378 ASP A C   1 
ATOM 1609 O O   . ASP A 1 346 ? 109.367 90.852  117.146 1.00 67.18  ? 378 ASP A O   1 
ATOM 1610 C CB  . ASP A 1 346 ? 109.321 88.366  119.330 1.00 55.74  ? 378 ASP A CB  1 
ATOM 1611 N N   . CYS A 1 347 ? 111.358 90.485  118.131 1.00 58.96  ? 379 CYS A N   1 
ATOM 1612 C CA  . CYS A 1 347 ? 111.776 91.870  117.945 1.00 61.26  ? 379 CYS A CA  1 
ATOM 1613 C C   . CYS A 1 347 ? 111.926 92.204  116.469 1.00 63.99  ? 379 CYS A C   1 
ATOM 1614 O O   . CYS A 1 347 ? 111.592 93.316  116.037 1.00 71.86  ? 379 CYS A O   1 
ATOM 1615 C CB  . CYS A 1 347 ? 113.083 92.131  118.689 1.00 68.61  ? 379 CYS A CB  1 
ATOM 1616 S SG  . CYS A 1 347 ? 112.911 92.234  120.478 1.00 85.16  ? 379 CYS A SG  1 
ATOM 1617 N N   . ARG A 1 348 ? 112.437 91.258  115.679 1.00 59.52  ? 380 ARG A N   1 
ATOM 1618 C CA  . ARG A 1 348 ? 112.561 91.483  114.244 1.00 55.21  ? 380 ARG A CA  1 
ATOM 1619 C C   . ARG A 1 348 ? 111.191 91.698  113.615 1.00 56.92  ? 380 ARG A C   1 
ATOM 1620 O O   . ARG A 1 348 ? 111.009 92.595  112.783 1.00 63.48  ? 380 ARG A O   1 
ATOM 1621 C CB  . ARG A 1 348 ? 113.290 90.303  113.603 1.00 52.67  ? 380 ARG A CB  1 
ATOM 1622 C CG  . ARG A 1 348 ? 113.569 90.451  112.128 1.00 57.92  ? 380 ARG A CG  1 
ATOM 1623 C CD  . ARG A 1 348 ? 114.347 89.258  111.609 1.00 57.18  ? 380 ARG A CD  1 
ATOM 1624 N NE  . ARG A 1 348 ? 114.672 89.390  110.195 1.00 58.69  ? 380 ARG A NE  1 
ATOM 1625 C CZ  . ARG A 1 348 ? 113.898 88.967  109.206 1.00 65.32  ? 380 ARG A CZ  1 
ATOM 1626 N NH1 . ARG A 1 348 ? 112.737 88.379  109.441 1.00 67.24  ? 380 ARG A NH1 1 
ATOM 1627 N NH2 . ARG A 1 348 ? 114.298 89.140  107.950 1.00 63.28  ? 380 ARG A NH2 1 
ATOM 1628 N N   . ASP A 1 349 ? 110.204 90.898  114.026 1.00 52.26  ? 381 ASP A N   1 
ATOM 1629 C CA  . ASP A 1 349 ? 108.844 91.089  113.526 1.00 45.02  ? 381 ASP A CA  1 
ATOM 1630 C C   . ASP A 1 349 ? 108.283 92.451  113.930 1.00 49.91  ? 381 ASP A C   1 
ATOM 1631 O O   . ASP A 1 349 ? 107.624 93.127  113.126 1.00 61.77  ? 381 ASP A O   1 
ATOM 1632 C CB  . ASP A 1 349 ? 107.943 89.967  114.035 1.00 52.84  ? 381 ASP A CB  1 
ATOM 1633 C CG  . ASP A 1 349 ? 106.693 89.793  113.201 1.00 64.08  ? 381 ASP A CG  1 
ATOM 1634 O OD1 . ASP A 1 349 ? 106.262 90.764  112.547 1.00 67.13  ? 381 ASP A OD1 1 
ATOM 1635 O OD2 . ASP A 1 349 ? 106.134 88.677  113.199 1.00 66.98  ? 381 ASP A OD2 1 
ATOM 1636 N N   . ILE A 1 350 ? 108.530 92.868  115.173 1.00 48.10  ? 382 ILE A N   1 
ATOM 1637 C CA  . ILE A 1 350 ? 108.010 94.150  115.647 1.00 51.98  ? 382 ILE A CA  1 
ATOM 1638 C C   . ILE A 1 350 ? 108.600 95.297  114.836 1.00 52.24  ? 382 ILE A C   1 
ATOM 1639 O O   . ILE A 1 350 ? 107.888 96.220  114.411 1.00 62.11  ? 382 ILE A O   1 
ATOM 1640 C CB  . ILE A 1 350 ? 108.292 94.322  117.150 1.00 53.27  ? 382 ILE A CB  1 
ATOM 1641 C CG1 . ILE A 1 350 ? 107.438 93.360  117.971 1.00 52.51  ? 382 ILE A CG1 1 
ATOM 1642 C CG2 . ILE A 1 350 ? 108.038 95.749  117.581 1.00 52.76  ? 382 ILE A CG2 1 
ATOM 1643 C CD1 . ILE A 1 350 ? 108.037 93.014  119.304 1.00 54.14  ? 382 ILE A CD1 1 
ATOM 1644 N N   . ILE A 1 351 ? 109.912 95.253  114.605 1.00 49.42  ? 383 ILE A N   1 
ATOM 1645 C CA  . ILE A 1 351 ? 110.557 96.304  113.826 1.00 48.60  ? 383 ILE A CA  1 
ATOM 1646 C C   . ILE A 1 351 ? 110.065 96.278  112.385 1.00 55.32  ? 383 ILE A C   1 
ATOM 1647 O O   . ILE A 1 351 ? 109.907 97.329  111.753 1.00 64.94  ? 383 ILE A O   1 
ATOM 1648 C CB  . ILE A 1 351 ? 112.087 96.177  113.912 1.00 51.34  ? 383 ILE A CB  1 
ATOM 1649 C CG1 . ILE A 1 351 ? 112.547 96.314  115.361 1.00 55.48  ? 383 ILE A CG1 1 
ATOM 1650 C CG2 . ILE A 1 351 ? 112.761 97.239  113.067 1.00 52.68  ? 383 ILE A CG2 1 
ATOM 1651 C CD1 . ILE A 1 351 ? 112.225 97.652  115.973 1.00 58.74  ? 383 ILE A CD1 1 
ATOM 1652 N N   . GLN A 1 352 ? 109.800 95.085  111.845 1.00 48.83  ? 384 GLN A N   1 
ATOM 1653 C CA  . GLN A 1 352 ? 109.241 94.994  110.500 1.00 41.30  ? 384 GLN A CA  1 
ATOM 1654 C C   . GLN A 1 352 ? 107.896 95.700  110.416 1.00 49.67  ? 384 GLN A C   1 
ATOM 1655 O O   . GLN A 1 352 ? 107.637 96.456  109.474 1.00 61.68  ? 384 GLN A O   1 
ATOM 1656 C CB  . GLN A 1 352 ? 109.094 93.533  110.088 1.00 40.77  ? 384 GLN A CB  1 
ATOM 1657 C CG  . GLN A 1 352 ? 110.260 92.971  109.313 1.00 50.78  ? 384 GLN A CG  1 
ATOM 1658 C CD  . GLN A 1 352 ? 109.853 91.798  108.451 1.00 54.15  ? 384 GLN A CD  1 
ATOM 1659 O OE1 . GLN A 1 352 ? 108.682 91.642  108.116 1.00 53.29  ? 384 GLN A OE1 1 
ATOM 1660 N NE2 . GLN A 1 352 ? 110.817 90.965  108.088 1.00 53.43  ? 384 GLN A NE2 1 
ATOM 1661 N N   . ARG A 1 353 ? 107.021 95.457  111.391 1.00 50.74  ? 385 ARG A N   1 
ATOM 1662 C CA  . ARG A 1 353 ? 105.707 96.095  111.369 1.00 47.19  ? 385 ARG A CA  1 
ATOM 1663 C C   . ARG A 1 353 ? 105.824 97.608  111.508 1.00 50.90  ? 385 ARG A C   1 
ATOM 1664 O O   . ARG A 1 353 ? 105.132 98.365  110.809 1.00 61.61  ? 385 ARG A O   1 
ATOM 1665 C CB  . ARG A 1 353 ? 104.826 95.521  112.474 1.00 49.06  ? 385 ARG A CB  1 
ATOM 1666 C CG  . ARG A 1 353 ? 104.277 94.149  112.159 1.00 55.71  ? 385 ARG A CG  1 
ATOM 1667 C CD  . ARG A 1 353 ? 102.922 93.944  112.797 1.00 54.75  ? 385 ARG A CD  1 
ATOM 1668 N NE  . ARG A 1 353 ? 102.793 94.682  114.044 1.00 51.61  ? 385 ARG A NE  1 
ATOM 1669 C CZ  . ARG A 1 353 ? 103.114 94.196  115.234 1.00 61.49  ? 385 ARG A CZ  1 
ATOM 1670 N NH1 . ARG A 1 353 ? 103.596 92.973  115.373 1.00 65.34  ? 385 ARG A NH1 1 
ATOM 1671 N NH2 . ARG A 1 353 ? 102.950 94.957  116.312 1.00 62.38  ? 385 ARG A NH2 1 
ATOM 1672 N N   . MET A 1 354 ? 106.706 98.068  112.396 1.00 58.42  ? 386 MET A N   1 
ATOM 1673 C CA  . MET A 1 354 ? 106.919 99.504  112.541 1.00 57.93  ? 386 MET A CA  1 
ATOM 1674 C C   . MET A 1 354 ? 107.420 100.121 111.241 1.00 61.56  ? 386 MET A C   1 
ATOM 1675 O O   . MET A 1 354 ? 107.005 101.223 110.867 1.00 63.65  ? 386 MET A O   1 
ATOM 1676 C CB  . MET A 1 354 ? 107.901 99.775  113.678 1.00 60.60  ? 386 MET A CB  1 
ATOM 1677 C CG  . MET A 1 354 ? 108.040 101.237 114.048 1.00 65.15  ? 386 MET A CG  1 
ATOM 1678 S SD  . MET A 1 354 ? 109.165 101.490 115.434 1.00 86.43  ? 386 MET A SD  1 
ATOM 1679 C CE  . MET A 1 354 ? 109.054 99.905  116.256 1.00 63.72  ? 386 MET A CE  1 
ATOM 1680 N N   . HIS A 1 355 ? 108.317 99.427  110.540 1.00 57.99  ? 387 HIS A N   1 
ATOM 1681 C CA  . HIS A 1 355 ? 108.851 99.956  109.291 1.00 52.85  ? 387 HIS A CA  1 
ATOM 1682 C C   . HIS A 1 355 ? 107.801 99.957  108.188 1.00 53.95  ? 387 HIS A C   1 
ATOM 1683 O O   . HIS A 1 355 ? 107.788 100.857 107.342 1.00 57.51  ? 387 HIS A O   1 
ATOM 1684 C CB  . HIS A 1 355 ? 110.080 99.158  108.870 1.00 46.83  ? 387 HIS A CB  1 
ATOM 1685 C CG  . HIS A 1 355 ? 111.307 99.495  109.654 1.00 51.07  ? 387 HIS A CG  1 
ATOM 1686 N ND1 . HIS A 1 355 ? 112.536 98.931  109.395 1.00 66.93  ? 387 HIS A ND1 1 
ATOM 1687 C CD2 . HIS A 1 355 ? 111.493 100.342 110.693 1.00 53.52  ? 387 HIS A CD2 1 
ATOM 1688 C CE1 . HIS A 1 355 ? 113.426 99.415  110.243 1.00 62.98  ? 387 HIS A CE1 1 
ATOM 1689 N NE2 . HIS A 1 355 ? 112.819 100.273 111.041 1.00 57.84  ? 387 HIS A NE2 1 
ATOM 1690 N N   . LEU A 1 356 ? 106.922 98.952  108.168 1.00 46.23  ? 388 LEU A N   1 
ATOM 1691 C CA  . LEU A 1 356 ? 105.799 98.990  107.235 1.00 44.76  ? 388 LEU A CA  1 
ATOM 1692 C C   . LEU A 1 356 ? 104.923 100.205 107.491 1.00 48.67  ? 388 LEU A C   1 
ATOM 1693 O O   . LEU A 1 356 ? 104.492 100.879 106.549 1.00 51.02  ? 388 LEU A O   1 
ATOM 1694 C CB  . LEU A 1 356 ? 104.962 97.715  107.331 1.00 41.18  ? 388 LEU A CB  1 
ATOM 1695 C CG  . LEU A 1 356 ? 105.194 96.540  106.381 1.00 44.10  ? 388 LEU A CG  1 
ATOM 1696 C CD1 . LEU A 1 356 ? 106.480 95.811  106.673 1.00 49.21  ? 388 LEU A CD1 1 
ATOM 1697 C CD2 . LEU A 1 356 ? 104.024 95.581  106.449 1.00 46.38  ? 388 LEU A CD2 1 
ATOM 1698 N N   . ARG A 1 357 ? 104.640 100.496 108.761 1.00 56.82  ? 389 ARG A N   1 
ATOM 1699 C CA  . ARG A 1 357 ? 103.844 101.680 109.074 1.00 53.64  ? 389 ARG A CA  1 
ATOM 1700 C C   . ARG A 1 357 ? 104.564 102.961 108.667 1.00 53.64  ? 389 ARG A C   1 
ATOM 1701 O O   . ARG A 1 357 ? 103.942 103.891 108.144 1.00 53.34  ? 389 ARG A O   1 
ATOM 1702 C CB  . ARG A 1 357 ? 103.501 101.710 110.562 1.00 52.62  ? 389 ARG A CB  1 
ATOM 1703 N N   . GLN A 1 358 ? 105.876 103.025 108.896 1.00 57.90  ? 390 GLN A N   1 
ATOM 1704 C CA  . GLN A 1 358 ? 106.628 104.256 108.681 1.00 50.56  ? 390 GLN A CA  1 
ATOM 1705 C C   . GLN A 1 358 ? 106.866 104.547 107.205 1.00 48.25  ? 390 GLN A C   1 
ATOM 1706 O O   . GLN A 1 358 ? 106.765 105.700 106.776 1.00 50.49  ? 390 GLN A O   1 
ATOM 1707 C CB  . GLN A 1 358 ? 107.962 104.179 109.420 1.00 55.12  ? 390 GLN A CB  1 
ATOM 1708 C CG  . GLN A 1 358 ? 108.797 105.436 109.340 1.00 55.32  ? 390 GLN A CG  1 
ATOM 1709 C CD  . GLN A 1 358 ? 110.078 105.326 110.136 1.00 60.55  ? 390 GLN A CD  1 
ATOM 1710 O OE1 . GLN A 1 358 ? 110.366 104.287 110.726 1.00 59.94  ? 390 GLN A OE1 1 
ATOM 1711 N NE2 . GLN A 1 358 ? 110.857 106.400 110.156 1.00 63.75  ? 390 GLN A NE2 1 
ATOM 1712 N N   . TYR A 1 359 ? 107.183 103.526 106.412 1.00 49.47  ? 391 TYR A N   1 
ATOM 1713 C CA  . TYR A 1 359 ? 107.618 103.718 105.037 1.00 50.27  ? 391 TYR A CA  1 
ATOM 1714 C C   . TYR A 1 359 ? 106.460 103.744 104.046 1.00 57.55  ? 391 TYR A C   1 
ATOM 1715 O O   . TYR A 1 359 ? 106.665 103.460 102.861 1.00 62.60  ? 391 TYR A O   1 
ATOM 1716 C CB  . TYR A 1 359 ? 108.630 102.637 104.659 1.00 52.24  ? 391 TYR A CB  1 
ATOM 1717 C CG  . TYR A 1 359 ? 110.037 102.995 105.066 1.00 52.67  ? 391 TYR A CG  1 
ATOM 1718 C CD1 . TYR A 1 359 ? 110.482 102.764 106.356 1.00 57.83  ? 391 TYR A CD1 1 
ATOM 1719 C CD2 . TYR A 1 359 ? 110.914 103.576 104.169 1.00 58.85  ? 391 TYR A CD2 1 
ATOM 1720 C CE1 . TYR A 1 359 ? 111.760 103.096 106.739 1.00 57.30  ? 391 TYR A CE1 1 
ATOM 1721 C CE2 . TYR A 1 359 ? 112.195 103.912 104.543 1.00 57.56  ? 391 TYR A CE2 1 
ATOM 1722 C CZ  . TYR A 1 359 ? 112.612 103.669 105.829 1.00 58.35  ? 391 TYR A CZ  1 
ATOM 1723 O OH  . TYR A 1 359 ? 113.891 104.001 106.208 1.00 65.38  ? 391 TYR A OH  1 
ATOM 1724 N N   . GLU A 1 360 ? 105.293 104.114 104.478 1.00 56.09  ? 392 GLU A N   1 
ATOM 1725 C CA  . GLU A 1 360 ? 104.126 104.252 103.657 1.00 52.44  ? 392 GLU A CA  1 
ATOM 1726 C C   . GLU A 1 360 ? 103.636 103.120 102.867 1.00 51.25  ? 392 GLU A C   1 
ATOM 1727 O O   . GLU A 1 360 ? 103.314 103.267 101.735 1.00 62.24  ? 392 GLU A O   1 
ATOM 1728 C CB  . GLU A 1 360 ? 104.190 105.495 102.810 1.00 30.00  ? 392 GLU A CB  1 
ATOM 1729 C CG  . GLU A 1 360 ? 104.267 106.754 103.614 1.00 30.00  ? 392 GLU A CG  1 
ATOM 1730 C CD  . GLU A 1 360 ? 104.332 107.953 102.725 1.00 30.00  ? 392 GLU A CD  1 
ATOM 1731 O OE1 . GLU A 1 360 ? 104.054 107.792 101.521 1.00 30.00  ? 392 GLU A OE1 1 
ATOM 1732 O OE2 . GLU A 1 360 ? 104.661 109.051 103.219 1.00 30.00  ? 392 GLU A OE2 1 
ATOM 1733 N N   . LEU A 1 361 ? 103.520 101.980 103.484 1.00 45.14  ? 393 LEU A N   1 
ATOM 1734 C CA  . LEU A 1 361 ? 102.961 100.788 102.860 1.00 44.62  ? 393 LEU A CA  1 
ATOM 1735 C C   . LEU A 1 361 ? 101.568 100.449 103.360 1.00 56.08  ? 393 LEU A C   1 
ATOM 1736 O O   . LEU A 1 361 ? 100.722 100.028 102.570 1.00 60.73  ? 393 LEU A O   1 
ATOM 1737 C CB  . LEU A 1 361 ? 103.881 99.584  103.078 1.00 43.75  ? 393 LEU A CB  1 
ATOM 1738 C CG  . LEU A 1 361 ? 105.074 99.459  102.137 1.00 39.50  ? 393 LEU A CG  1 
ATOM 1739 C CD1 . LEU A 1 361 ? 106.013 98.374  102.612 1.00 49.11  ? 393 LEU A CD1 1 
ATOM 1740 C CD2 . LEU A 1 361 ? 104.589 99.161  100.740 1.00 46.35  ? 393 LEU A CD2 1 
ATOM 1741 N N   . LEU A 1 362 ? 101.303 100.624 104.650 1.00 69.25  ? 394 LEU A N   1 
ATOM 1742 C CA  . LEU A 1 362 ? 99.962  100.419 105.184 1.00 68.84  ? 394 LEU A CA  1 
ATOM 1743 C C   . LEU A 1 362 ? 99.494  101.657 105.941 1.00 72.05  ? 394 LEU A C   1 
ATOM 1744 O O   . LEU A 1 362 ? 99.486  102.762 105.399 1.00 72.30  ? 394 LEU A O   1 
ATOM 1745 C CB  . LEU A 1 362 ? 99.918  99.188  106.094 1.00 64.82  ? 394 LEU A CB  1 
ATOM 1746 C CG  . LEU A 1 362 ? 100.815 99.143  107.331 1.00 71.33  ? 394 LEU A CG  1 
ATOM 1747 C CD1 . LEU A 1 362 ? 100.100 99.683  108.562 1.00 69.27  ? 394 LEU A CD1 1 
ATOM 1748 C CD2 . LEU A 1 362 ? 101.289 97.723  107.578 1.00 72.90  ? 394 LEU A CD2 1 
ATOM 1749 N N   . GLU B 2 8   ? 90.688  101.634 173.189 1.00 177.07 ? 3   GLU B N   1 
ATOM 1750 C CA  . GLU B 2 8   ? 89.706  100.956 172.352 1.00 177.07 ? 3   GLU B CA  1 
ATOM 1751 C C   . GLU B 2 8   ? 89.767  101.470 170.917 1.00 177.07 ? 3   GLU B C   1 
ATOM 1752 O O   . GLU B 2 8   ? 89.853  102.676 170.684 1.00 177.07 ? 3   GLU B O   1 
ATOM 1753 C CB  . GLU B 2 8   ? 88.298  101.140 172.919 1.00 177.07 ? 3   GLU B CB  1 
ATOM 1754 N N   . LEU B 2 9   ? 89.728  100.543 169.959 1.00 177.42 ? 4   LEU B N   1 
ATOM 1755 C CA  . LEU B 2 9   ? 89.783  100.925 168.551 1.00 177.42 ? 4   LEU B CA  1 
ATOM 1756 C C   . LEU B 2 9   ? 88.570  101.759 168.158 1.00 177.42 ? 4   LEU B C   1 
ATOM 1757 O O   . LEU B 2 9   ? 88.697  102.762 167.446 1.00 177.42 ? 4   LEU B O   1 
ATOM 1758 C CB  . LEU B 2 9   ? 89.889  99.678  167.674 1.00 177.42 ? 4   LEU B CB  1 
ATOM 1759 N N   . ASP B 2 10  ? 87.380  101.355 168.611 1.00 176.68 ? 5   ASP B N   1 
ATOM 1760 C CA  . ASP B 2 10  ? 86.174  102.113 168.293 1.00 176.68 ? 5   ASP B CA  1 
ATOM 1761 C C   . ASP B 2 10  ? 86.217  103.504 168.910 1.00 176.68 ? 5   ASP B C   1 
ATOM 1762 O O   . ASP B 2 10  ? 85.847  104.491 168.261 1.00 176.68 ? 5   ASP B O   1 
ATOM 1763 C CB  . ASP B 2 10  ? 84.936  101.353 168.770 1.00 176.68 ? 5   ASP B CB  1 
ATOM 1764 N N   . GLN B 2 11  ? 86.666  103.603 170.164 1.00 175.74 ? 6   GLN B N   1 
ATOM 1765 C CA  . GLN B 2 11  ? 86.770  104.906 170.813 1.00 175.74 ? 6   GLN B CA  1 
ATOM 1766 C C   . GLN B 2 11  ? 87.767  105.802 170.093 1.00 175.74 ? 6   GLN B C   1 
ATOM 1767 O O   . GLN B 2 11  ? 87.509  106.993 169.890 1.00 175.74 ? 6   GLN B O   1 
ATOM 1768 C CB  . GLN B 2 11  ? 87.165  104.731 172.279 1.00 175.74 ? 6   GLN B CB  1 
ATOM 1769 N N   . LEU B 2 12  ? 88.915  105.244 169.698 1.00 175.19 ? 7   LEU B N   1 
ATOM 1770 C CA  . LEU B 2 12  ? 89.912  106.032 168.980 1.00 175.19 ? 7   LEU B CA  1 
ATOM 1771 C C   . LEU B 2 12  ? 89.384  106.493 167.628 1.00 175.19 ? 7   LEU B C   1 
ATOM 1772 O O   . LEU B 2 12  ? 89.607  107.643 167.229 1.00 175.19 ? 7   LEU B O   1 
ATOM 1773 C CB  . LEU B 2 12  ? 91.196  105.221 168.808 1.00 175.19 ? 7   LEU B CB  1 
ATOM 1774 N N   . ARG B 2 13  ? 88.682  105.613 166.909 1.00 174.10 ? 8   ARG B N   1 
ATOM 1775 C CA  . ARG B 2 13  ? 88.113  105.997 165.621 1.00 174.10 ? 8   ARG B CA  1 
ATOM 1776 C C   . ARG B 2 13  ? 87.074  107.098 165.784 1.00 174.10 ? 8   ARG B C   1 
ATOM 1777 O O   . ARG B 2 13  ? 87.046  108.059 165.003 1.00 174.10 ? 8   ARG B O   1 
ATOM 1778 C CB  . ARG B 2 13  ? 87.502  104.777 164.933 1.00 174.10 ? 8   ARG B CB  1 
ATOM 1779 N N   . GLN B 2 14  ? 86.211  106.978 166.796 1.00 170.85 ? 9   GLN B N   1 
ATOM 1780 C CA  . GLN B 2 14  ? 85.213  108.011 167.042 1.00 170.85 ? 9   GLN B CA  1 
ATOM 1781 C C   . GLN B 2 14  ? 85.870  109.337 167.402 1.00 170.85 ? 9   GLN B C   1 
ATOM 1782 O O   . GLN B 2 14  ? 85.441  110.396 166.928 1.00 170.85 ? 9   GLN B O   1 
ATOM 1783 C CB  . GLN B 2 14  ? 84.258  107.565 168.150 1.00 170.85 ? 9   GLN B CB  1 
ATOM 1784 N N   . GLU B 2 15  ? 86.909  109.298 168.239 1.00 168.90 ? 10  GLU B N   1 
ATOM 1785 C CA  . GLU B 2 15  ? 87.611  110.523 168.613 1.00 168.90 ? 10  GLU B CA  1 
ATOM 1786 C C   . GLU B 2 15  ? 88.262  111.172 167.399 1.00 168.90 ? 10  GLU B C   1 
ATOM 1787 O O   . GLU B 2 15  ? 88.211  112.396 167.233 1.00 168.90 ? 10  GLU B O   1 
ATOM 1788 C CB  . GLU B 2 15  ? 88.654  110.219 169.688 1.00 168.90 ? 10  GLU B CB  1 
ATOM 1789 N N   . ALA B 2 16  ? 88.882  110.363 166.537 1.00 166.34 ? 11  ALA B N   1 
ATOM 1790 C CA  . ALA B 2 16  ? 89.511  110.906 165.337 1.00 166.34 ? 11  ALA B CA  1 
ATOM 1791 C C   . ALA B 2 16  ? 88.479  111.530 164.408 1.00 166.34 ? 11  ALA B C   1 
ATOM 1792 O O   . ALA B 2 16  ? 88.706  112.615 163.857 1.00 166.34 ? 11  ALA B O   1 
ATOM 1793 C CB  . ALA B 2 16  ? 90.296  109.812 164.615 1.00 166.34 ? 11  ALA B CB  1 
ATOM 1794 N N   . GLU B 2 17  ? 87.338  110.863 164.221 1.00 163.55 ? 12  GLU B N   1 
ATOM 1795 C CA  . GLU B 2 17  ? 86.290  111.413 163.366 1.00 163.55 ? 12  GLU B CA  1 
ATOM 1796 C C   . GLU B 2 17  ? 85.750  112.719 163.936 1.00 163.55 ? 12  GLU B C   1 
ATOM 1797 O O   . GLU B 2 17  ? 85.526  113.689 163.200 1.00 163.55 ? 12  GLU B O   1 
ATOM 1798 C CB  . GLU B 2 17  ? 85.166  110.391 163.192 1.00 163.55 ? 12  GLU B CB  1 
ATOM 1799 N N   . GLN B 2 18  ? 85.535  112.761 165.254 1.00 159.55 ? 13  GLN B N   1 
ATOM 1800 C CA  . GLN B 2 18  ? 85.040  113.979 165.884 1.00 159.55 ? 13  GLN B CA  1 
ATOM 1801 C C   . GLN B 2 18  ? 86.043  115.117 165.749 1.00 159.55 ? 13  GLN B C   1 
ATOM 1802 O O   . GLN B 2 18  ? 85.660  116.263 165.490 1.00 159.55 ? 13  GLN B O   1 
ATOM 1803 C CB  . GLN B 2 18  ? 84.721  113.715 167.355 1.00 159.55 ? 13  GLN B CB  1 
ATOM 1804 N N   . LEU B 2 19  ? 87.334  114.823 165.922 1.00 156.66 ? 14  LEU B N   1 
ATOM 1805 C CA  . LEU B 2 19  ? 88.348  115.865 165.803 1.00 156.66 ? 14  LEU B CA  1 
ATOM 1806 C C   . LEU B 2 19  ? 88.458  116.362 164.366 1.00 156.66 ? 14  LEU B C   1 
ATOM 1807 O O   . LEU B 2 19  ? 88.670  117.557 164.130 1.00 156.66 ? 14  LEU B O   1 
ATOM 1808 C CB  . LEU B 2 19  ? 89.693  115.347 166.308 1.00 156.66 ? 14  LEU B CB  1 
ATOM 1809 C CG  . LEU B 2 19  ? 90.808  116.381 166.457 1.00 156.66 ? 14  LEU B CG  1 
ATOM 1810 C CD1 . LEU B 2 19  ? 90.412  117.446 167.462 1.00 156.66 ? 14  LEU B CD1 1 
ATOM 1811 C CD2 . LEU B 2 19  ? 92.100  115.708 166.883 1.00 156.66 ? 14  LEU B CD2 1 
ATOM 1812 N N   . LYS B 2 20  ? 88.321  115.459 163.392 1.00 155.16 ? 15  LYS B N   1 
ATOM 1813 C CA  . LYS B 2 20  ? 88.307  115.881 161.994 1.00 155.16 ? 15  LYS B CA  1 
ATOM 1814 C C   . LYS B 2 20  ? 87.110  116.777 161.703 1.00 155.16 ? 15  LYS B C   1 
ATOM 1815 O O   . LYS B 2 20  ? 87.238  117.795 161.011 1.00 155.16 ? 15  LYS B O   1 
ATOM 1816 C CB  . LYS B 2 20  ? 88.301  114.658 161.076 1.00 155.16 ? 15  LYS B CB  1 
ATOM 1817 N N   . ASN B 2 21  ? 85.936  116.418 162.226 1.00 152.34 ? 16  ASN B N   1 
ATOM 1818 C CA  . ASN B 2 21  ? 84.768  117.276 162.060 1.00 152.34 ? 16  ASN B CA  1 
ATOM 1819 C C   . ASN B 2 21  ? 84.996  118.637 162.705 1.00 152.34 ? 16  ASN B C   1 
ATOM 1820 O O   . ASN B 2 21  ? 84.622  119.672 162.141 1.00 152.34 ? 16  ASN B O   1 
ATOM 1821 C CB  . ASN B 2 21  ? 83.531  116.600 162.650 1.00 152.34 ? 16  ASN B CB  1 
ATOM 1822 N N   . GLN B 2 22  ? 85.616  118.653 163.887 1.00 150.79 ? 17  GLN B N   1 
ATOM 1823 C CA  . GLN B 2 22  ? 85.889  119.914 164.569 1.00 150.79 ? 17  GLN B CA  1 
ATOM 1824 C C   . GLN B 2 22  ? 86.842  120.788 163.764 1.00 150.79 ? 17  GLN B C   1 
ATOM 1825 O O   . GLN B 2 22  ? 86.630  122.001 163.643 1.00 150.79 ? 17  GLN B O   1 
ATOM 1826 C CB  . GLN B 2 22  ? 86.458  119.637 165.961 1.00 150.79 ? 17  GLN B CB  1 
ATOM 1827 C CG  . GLN B 2 22  ? 86.670  120.876 166.819 1.00 150.79 ? 17  GLN B CG  1 
ATOM 1828 C CD  . GLN B 2 22  ? 88.045  121.488 166.634 1.00 150.79 ? 17  GLN B CD  1 
ATOM 1829 O OE1 . GLN B 2 22  ? 89.009  120.793 166.313 1.00 150.79 ? 17  GLN B OE1 1 
ATOM 1830 N NE2 . GLN B 2 22  ? 88.143  122.797 166.837 1.00 150.79 ? 17  GLN B NE2 1 
ATOM 1831 N N   . ILE B 2 23  ? 87.900  120.194 163.206 1.00 146.53 ? 18  ILE B N   1 
ATOM 1832 C CA  . ILE B 2 23  ? 88.861  120.985 162.443 1.00 146.53 ? 18  ILE B CA  1 
ATOM 1833 C C   . ILE B 2 23  ? 88.241  121.463 161.135 1.00 146.53 ? 18  ILE B C   1 
ATOM 1834 O O   . ILE B 2 23  ? 88.599  122.528 160.619 1.00 146.53 ? 18  ILE B O   1 
ATOM 1835 C CB  . ILE B 2 23  ? 90.165  120.194 162.216 1.00 146.53 ? 18  ILE B CB  1 
ATOM 1836 C CG1 . ILE B 2 23  ? 91.309  121.146 161.865 1.00 146.53 ? 18  ILE B CG1 1 
ATOM 1837 C CG2 . ILE B 2 23  ? 90.009  119.162 161.116 1.00 146.53 ? 18  ILE B CG2 1 
ATOM 1838 C CD1 . ILE B 2 23  ? 91.728  122.042 163.009 1.00 146.53 ? 18  ILE B CD1 1 
ATOM 1839 N N   . ARG B 2 24  ? 87.301  120.694 160.579 1.00 142.84 ? 19  ARG B N   1 
ATOM 1840 C CA  . ARG B 2 24  ? 86.600  121.150 159.381 1.00 142.84 ? 19  ARG B CA  1 
ATOM 1841 C C   . ARG B 2 24  ? 85.634  122.281 159.707 1.00 142.84 ? 19  ARG B C   1 
ATOM 1842 O O   . ARG B 2 24  ? 85.393  123.164 158.874 1.00 142.84 ? 19  ARG B O   1 
ATOM 1843 C CB  . ARG B 2 24  ? 85.861  119.983 158.728 1.00 142.84 ? 19  ARG B CB  1 
ATOM 1844 N N   . ASP B 2 25  ? 85.060  122.260 160.913 1.00 139.22 ? 20  ASP B N   1 
ATOM 1845 C CA  . ASP B 2 25  ? 84.118  123.302 161.307 1.00 139.22 ? 20  ASP B CA  1 
ATOM 1846 C C   . ASP B 2 25  ? 84.788  124.670 161.349 1.00 139.22 ? 20  ASP B C   1 
ATOM 1847 O O   . ASP B 2 25  ? 84.204  125.669 160.914 1.00 139.22 ? 20  ASP B O   1 
ATOM 1848 C CB  . ASP B 2 25  ? 83.500  122.965 162.662 1.00 139.22 ? 20  ASP B CB  1 
ATOM 1849 N N   . ALA B 2 26  ? 86.012  124.738 161.878 1.00 133.11 ? 21  ALA B N   1 
ATOM 1850 C CA  . ALA B 2 26  ? 86.725  126.010 161.922 1.00 133.11 ? 21  ALA B CA  1 
ATOM 1851 C C   . ALA B 2 26  ? 86.996  126.536 160.519 1.00 133.11 ? 21  ALA B C   1 
ATOM 1852 O O   . ALA B 2 26  ? 86.838  127.735 160.254 1.00 133.11 ? 21  ALA B O   1 
ATOM 1853 C CB  . ALA B 2 26  ? 88.028  125.855 162.702 1.00 133.11 ? 21  ALA B CB  1 
ATOM 1854 N N   . ARG B 2 27  ? 87.405  125.651 159.605 1.00 127.49 ? 22  ARG B N   1 
ATOM 1855 C CA  . ARG B 2 27  ? 87.613  126.058 158.219 1.00 127.49 ? 22  ARG B CA  1 
ATOM 1856 C C   . ARG B 2 27  ? 86.327  126.587 157.603 1.00 127.49 ? 22  ARG B C   1 
ATOM 1857 O O   . ARG B 2 27  ? 86.337  127.613 156.912 1.00 127.49 ? 22  ARG B O   1 
ATOM 1858 C CB  . ARG B 2 27  ? 88.144  124.883 157.397 1.00 127.49 ? 22  ARG B CB  1 
ATOM 1859 C CG  . ARG B 2 27  ? 89.571  124.472 157.704 1.00 127.49 ? 22  ARG B CG  1 
ATOM 1860 C CD  . ARG B 2 27  ? 89.999  123.333 156.790 1.00 127.49 ? 22  ARG B CD  1 
ATOM 1861 N NE  . ARG B 2 27  ? 91.382  122.929 157.013 1.00 127.49 ? 22  ARG B NE  1 
ATOM 1862 C CZ  . ARG B 2 27  ? 91.983  121.942 156.360 1.00 127.49 ? 22  ARG B CZ  1 
ATOM 1863 N NH1 . ARG B 2 27  ? 91.321  121.256 155.439 1.00 127.49 ? 22  ARG B NH1 1 
ATOM 1864 N NH2 . ARG B 2 27  ? 93.247  121.639 156.625 1.00 127.49 ? 22  ARG B NH2 1 
ATOM 1865 N N   . LYS B 2 28  ? 85.209  125.897 157.838 1.00 130.89 ? 23  LYS B N   1 
ATOM 1866 C CA  . LYS B 2 28  ? 83.937  126.347 157.283 1.00 130.89 ? 23  LYS B CA  1 
ATOM 1867 C C   . LYS B 2 28  ? 83.525  127.691 157.868 1.00 130.89 ? 23  LYS B C   1 
ATOM 1868 O O   . LYS B 2 28  ? 82.914  128.518 157.180 1.00 130.89 ? 23  LYS B O   1 
ATOM 1869 C CB  . LYS B 2 28  ? 82.854  125.298 157.533 1.00 130.89 ? 23  LYS B CB  1 
ATOM 1870 N N   . ALA B 2 29  ? 83.847  127.926 159.140 1.00 130.66 ? 24  ALA B N   1 
ATOM 1871 C CA  . ALA B 2 29  ? 83.445  129.171 159.786 1.00 130.66 ? 24  ALA B CA  1 
ATOM 1872 C C   . ALA B 2 29  ? 84.288  130.347 159.310 1.00 130.66 ? 24  ALA B C   1 
ATOM 1873 O O   . ALA B 2 29  ? 83.763  131.442 159.078 1.00 130.66 ? 24  ALA B O   1 
ATOM 1874 C CB  . ALA B 2 29  ? 83.535  129.026 161.306 1.00 130.66 ? 24  ALA B CB  1 
ATOM 1875 N N   . CYS B 2 30  ? 85.597  130.143 159.157 1.00 128.49 ? 25  CYS B N   1 
ATOM 1876 C CA  . CYS B 2 30  ? 86.484  131.253 158.827 1.00 128.49 ? 25  CYS B CA  1 
ATOM 1877 C C   . CYS B 2 30  ? 86.311  131.760 157.400 1.00 128.49 ? 25  CYS B C   1 
ATOM 1878 O O   . CYS B 2 30  ? 86.800  132.853 157.094 1.00 128.49 ? 25  CYS B O   1 
ATOM 1879 C CB  . CYS B 2 30  ? 87.940  130.848 159.051 1.00 128.49 ? 25  CYS B CB  1 
ATOM 1880 S SG  . CYS B 2 30  ? 88.363  130.514 160.775 1.00 128.49 ? 25  CYS B SG  1 
ATOM 1881 N N   . ALA B 2 31  ? 85.646  131.007 156.528 1.00 127.66 ? 26  ALA B N   1 
ATOM 1882 C CA  . ALA B 2 31  ? 85.457  131.451 155.153 1.00 127.66 ? 26  ALA B CA  1 
ATOM 1883 C C   . ALA B 2 31  ? 84.606  132.714 155.115 1.00 127.66 ? 26  ALA B C   1 
ATOM 1884 O O   . ALA B 2 31  ? 83.552  132.787 155.754 1.00 127.66 ? 26  ALA B O   1 
ATOM 1885 C CB  . ALA B 2 31  ? 84.804  130.345 154.325 1.00 127.66 ? 26  ALA B CB  1 
ATOM 1886 N N   . ASP B 2 32  ? 85.066  133.713 154.363 1.00 124.06 ? 27  ASP B N   1 
ATOM 1887 C CA  . ASP B 2 32  ? 84.394  135.005 154.313 1.00 124.06 ? 27  ASP B CA  1 
ATOM 1888 C C   . ASP B 2 32  ? 83.820  135.330 152.944 1.00 124.06 ? 27  ASP B C   1 
ATOM 1889 O O   . ASP B 2 32  ? 82.613  135.571 152.828 1.00 124.06 ? 27  ASP B O   1 
ATOM 1890 C CB  . ASP B 2 32  ? 85.363  136.115 154.749 1.00 124.06 ? 27  ASP B CB  1 
ATOM 1891 C CG  . ASP B 2 32  ? 84.664  137.439 154.991 1.00 124.06 ? 27  ASP B CG  1 
ATOM 1892 O OD1 . ASP B 2 32  ? 84.167  138.041 154.017 1.00 124.06 ? 27  ASP B OD1 1 
ATOM 1893 O OD2 . ASP B 2 32  ? 84.609  137.878 156.158 1.00 124.06 ? 27  ASP B OD2 1 
ATOM 1894 N N   . ALA B 2 33  ? 84.645  135.348 151.899 1.00 121.03 ? 28  ALA B N   1 
ATOM 1895 C CA  . ALA B 2 33  ? 84.181  135.792 150.594 1.00 121.03 ? 28  ALA B CA  1 
ATOM 1896 C C   . ALA B 2 33  ? 85.087  135.228 149.509 1.00 121.03 ? 28  ALA B C   1 
ATOM 1897 O O   . ALA B 2 33  ? 86.286  135.041 149.726 1.00 121.03 ? 28  ALA B O   1 
ATOM 1898 C CB  . ALA B 2 33  ? 84.144  137.323 150.510 1.00 121.03 ? 28  ALA B CB  1 
ATOM 1899 N N   . THR B 2 34  ? 84.499  134.963 148.345 1.00 116.73 ? 29  THR B N   1 
ATOM 1900 C CA  . THR B 2 34  ? 85.260  134.472 147.206 1.00 116.73 ? 29  THR B CA  1 
ATOM 1901 C C   . THR B 2 34  ? 86.223  135.540 146.701 1.00 116.73 ? 29  THR B C   1 
ATOM 1902 O O   . THR B 2 34  ? 85.967  136.742 146.807 1.00 116.73 ? 29  THR B O   1 
ATOM 1903 C CB  . THR B 2 34  ? 84.323  134.046 146.078 1.00 116.73 ? 29  THR B CB  1 
ATOM 1904 N N   . LEU B 2 35  ? 87.350  135.084 146.149 1.00 110.92 ? 30  LEU B N   1 
ATOM 1905 C CA  . LEU B 2 35  ? 88.343  136.015 145.623 1.00 110.92 ? 30  LEU B CA  1 
ATOM 1906 C C   . LEU B 2 35  ? 87.794  136.790 144.431 1.00 110.92 ? 30  LEU B C   1 
ATOM 1907 O O   . LEU B 2 35  ? 88.202  137.932 144.181 1.00 110.92 ? 30  LEU B O   1 
ATOM 1908 C CB  . LEU B 2 35  ? 89.614  135.255 145.240 1.00 110.92 ? 30  LEU B CB  1 
ATOM 1909 C CG  . LEU B 2 35  ? 90.823  136.072 144.782 1.00 110.92 ? 30  LEU B CG  1 
ATOM 1910 C CD1 . LEU B 2 35  ? 91.239  137.051 145.856 1.00 110.92 ? 30  LEU B CD1 1 
ATOM 1911 C CD2 . LEU B 2 35  ? 91.980  135.163 144.423 1.00 110.92 ? 30  LEU B CD2 1 
ATOM 1912 N N   . SER B 2 36  ? 86.863  136.189 143.689 1.00 112.29 ? 31  SER B N   1 
ATOM 1913 C CA  . SER B 2 36  ? 86.288  136.848 142.523 1.00 112.29 ? 31  SER B CA  1 
ATOM 1914 C C   . SER B 2 36  ? 85.511  138.103 142.882 1.00 112.29 ? 31  SER B C   1 
ATOM 1915 O O   . SER B 2 36  ? 85.374  138.990 142.032 1.00 112.29 ? 31  SER B O   1 
ATOM 1916 C CB  . SER B 2 36  ? 85.379  135.878 141.766 1.00 112.29 ? 31  SER B CB  1 
ATOM 1917 O OG  . SER B 2 36  ? 86.119  134.791 141.239 1.00 112.29 ? 31  SER B OG  1 
ATOM 1918 N N   . GLN B 2 37  ? 85.003  138.203 144.109 1.00 112.90 ? 32  GLN B N   1 
ATOM 1919 C CA  . GLN B 2 37  ? 84.276  139.392 144.531 1.00 112.90 ? 32  GLN B CA  1 
ATOM 1920 C C   . GLN B 2 37  ? 85.206  140.565 144.812 1.00 112.90 ? 32  GLN B C   1 
ATOM 1921 O O   . GLN B 2 37  ? 84.865  141.712 144.500 1.00 112.90 ? 32  GLN B O   1 
ATOM 1922 C CB  . GLN B 2 37  ? 83.441  139.083 145.774 1.00 112.90 ? 32  GLN B CB  1 
ATOM 1923 C CG  . GLN B 2 37  ? 82.342  138.067 145.532 1.00 112.90 ? 32  GLN B CG  1 
ATOM 1924 C CD  . GLN B 2 37  ? 81.371  138.511 144.458 1.00 112.90 ? 32  GLN B CD  1 
ATOM 1925 O OE1 . GLN B 2 37  ? 81.369  137.979 143.349 1.00 112.90 ? 32  GLN B OE1 1 
ATOM 1926 N NE2 . GLN B 2 37  ? 80.539  139.493 144.785 1.00 112.90 ? 32  GLN B NE2 1 
ATOM 1927 N N   . ILE B 2 38  ? 86.377  140.302 145.394 1.00 109.33 ? 33  ILE B N   1 
ATOM 1928 C CA  . ILE B 2 38  ? 87.296  141.387 145.712 1.00 109.33 ? 33  ILE B CA  1 
ATOM 1929 C C   . ILE B 2 38  ? 88.171  141.726 144.513 1.00 109.33 ? 33  ILE B C   1 
ATOM 1930 O O   . ILE B 2 38  ? 88.710  142.836 144.426 1.00 109.33 ? 33  ILE B O   1 
ATOM 1931 C CB  . ILE B 2 38  ? 88.140  141.022 146.948 1.00 109.33 ? 33  ILE B CB  1 
ATOM 1932 C CG1 . ILE B 2 38  ? 88.887  142.246 147.479 1.00 109.33 ? 33  ILE B CG1 1 
ATOM 1933 C CG2 . ILE B 2 38  ? 89.117  139.913 146.623 1.00 109.33 ? 33  ILE B CG2 1 
ATOM 1934 C CD1 . ILE B 2 38  ? 89.440  142.061 148.871 1.00 109.33 ? 33  ILE B CD1 1 
ATOM 1935 N N   . THR B 2 39  ? 88.316  140.800 143.565 1.00 109.46 ? 34  THR B N   1 
ATOM 1936 C CA  . THR B 2 39  ? 89.206  141.013 142.433 1.00 109.46 ? 34  THR B CA  1 
ATOM 1937 C C   . THR B 2 39  ? 88.520  141.637 141.224 1.00 109.46 ? 34  THR B C   1 
ATOM 1938 O O   . THR B 2 39  ? 89.197  141.918 140.229 1.00 109.46 ? 34  THR B O   1 
ATOM 1939 C CB  . THR B 2 39  ? 89.848  139.689 142.007 1.00 109.46 ? 34  THR B CB  1 
ATOM 1940 O OG1 . THR B 2 39  ? 88.852  138.661 141.969 1.00 109.46 ? 34  THR B OG1 1 
ATOM 1941 C CG2 . THR B 2 39  ? 90.939  139.292 142.983 1.00 109.46 ? 34  THR B CG2 1 
ATOM 1942 N N   . ASN B 2 40  ? 87.209  141.863 141.277 1.00 110.80 ? 35  ASN B N   1 
ATOM 1943 C CA  . ASN B 2 40  ? 86.481  142.362 140.115 1.00 110.80 ? 35  ASN B CA  1 
ATOM 1944 C C   . ASN B 2 40  ? 86.658  143.862 139.909 1.00 110.80 ? 35  ASN B C   1 
ATOM 1945 O O   . ASN B 2 40  ? 85.932  144.473 139.118 1.00 110.80 ? 35  ASN B O   1 
ATOM 1946 C CB  . ASN B 2 40  ? 84.996  141.975 140.225 1.00 110.80 ? 35  ASN B CB  1 
ATOM 1947 C CG  . ASN B 2 40  ? 84.236  142.752 141.304 1.00 110.80 ? 35  ASN B CG  1 
ATOM 1948 O OD1 . ASN B 2 40  ? 84.501  143.921 141.576 1.00 110.80 ? 35  ASN B OD1 1 
ATOM 1949 N ND2 . ASN B 2 40  ? 83.273  142.080 141.924 1.00 110.80 ? 35  ASN B ND2 1 
ATOM 1950 N N   . ASN B 2 41  ? 87.615  144.466 140.612 1.00 108.39 ? 36  ASN B N   1 
ATOM 1951 C CA  . ASN B 2 41  ? 87.892  145.892 140.501 1.00 108.39 ? 36  ASN B CA  1 
ATOM 1952 C C   . ASN B 2 41  ? 89.279  146.163 139.925 1.00 108.39 ? 36  ASN B C   1 
ATOM 1953 O O   . ASN B 2 41  ? 89.829  147.251 140.104 1.00 108.39 ? 36  ASN B O   1 
ATOM 1954 C CB  . ASN B 2 41  ? 87.738  146.571 141.860 1.00 108.39 ? 36  ASN B CB  1 
ATOM 1955 N N   . ILE B 2 42  ? 89.852  145.182 139.232 1.00 102.61 ? 37  ILE B N   1 
ATOM 1956 C CA  . ILE B 2 42  ? 91.192  145.289 138.667 1.00 102.61 ? 37  ILE B CA  1 
ATOM 1957 C C   . ILE B 2 42  ? 91.110  144.982 137.181 1.00 102.61 ? 37  ILE B C   1 
ATOM 1958 O O   . ILE B 2 42  ? 90.464  144.007 136.779 1.00 102.61 ? 37  ILE B O   1 
ATOM 1959 C CB  . ILE B 2 42  ? 92.192  144.346 139.364 1.00 102.61 ? 37  ILE B CB  1 
ATOM 1960 C CG1 . ILE B 2 42  ? 92.351  144.713 140.842 1.00 102.61 ? 37  ILE B CG1 1 
ATOM 1961 C CG2 . ILE B 2 42  ? 93.543  144.379 138.665 1.00 102.61 ? 37  ILE B CG2 1 
ATOM 1962 C CD1 . ILE B 2 42  ? 91.366  144.029 141.769 1.00 102.61 ? 37  ILE B CD1 1 
ATOM 1963 N N   . ASP B 2 43  ? 91.755  145.813 136.370 1.00 98.86  ? 38  ASP B N   1 
ATOM 1964 C CA  . ASP B 2 43  ? 91.686  145.650 134.926 1.00 98.86  ? 38  ASP B CA  1 
ATOM 1965 C C   . ASP B 2 43  ? 92.318  144.322 134.513 1.00 98.86  ? 38  ASP B C   1 
ATOM 1966 O O   . ASP B 2 43  ? 93.258  143.853 135.164 1.00 98.86  ? 38  ASP B O   1 
ATOM 1967 C CB  . ASP B 2 43  ? 92.393  146.811 134.225 1.00 98.86  ? 38  ASP B CB  1 
ATOM 1968 N N   . PRO B 2 44  ? 91.826  143.690 133.451 1.00 95.83  ? 39  PRO B N   1 
ATOM 1969 C CA  . PRO B 2 44  ? 92.401  142.413 133.016 1.00 95.83  ? 39  PRO B CA  1 
ATOM 1970 C C   . PRO B 2 44  ? 93.825  142.577 132.508 1.00 95.83  ? 39  PRO B C   1 
ATOM 1971 O O   . PRO B 2 44  ? 94.284  143.673 132.182 1.00 95.83  ? 39  PRO B O   1 
ATOM 1972 C CB  . PRO B 2 44  ? 91.463  141.964 131.891 1.00 95.83  ? 39  PRO B CB  1 
ATOM 1973 C CG  . PRO B 2 44  ? 90.194  142.697 132.139 1.00 95.83  ? 39  PRO B CG  1 
ATOM 1974 C CD  . PRO B 2 44  ? 90.602  144.021 132.707 1.00 95.83  ? 39  PRO B CD  1 
ATOM 1975 N N   . VAL B 2 45  ? 94.530  141.443 132.451 1.00 91.80  ? 40  VAL B N   1 
ATOM 1976 C CA  . VAL B 2 45  ? 95.931  141.447 132.048 1.00 91.80  ? 40  VAL B CA  1 
ATOM 1977 C C   . VAL B 2 45  ? 96.114  141.889 130.606 1.00 91.80  ? 40  VAL B C   1 
ATOM 1978 O O   . VAL B 2 45  ? 97.196  142.359 130.240 1.00 91.80  ? 40  VAL B O   1 
ATOM 1979 C CB  . VAL B 2 45  ? 96.549  140.052 132.243 1.00 91.80  ? 40  VAL B CB  1 
ATOM 1980 C CG1 . VAL B 2 45  ? 96.511  139.656 133.702 1.00 91.80  ? 40  VAL B CG1 1 
ATOM 1981 C CG2 . VAL B 2 45  ? 95.820  139.024 131.394 1.00 91.80  ? 40  VAL B CG2 1 
ATOM 1982 N N   . GLY B 2 46  ? 95.088  141.755 129.774 1.00 93.57  ? 41  GLY B N   1 
ATOM 1983 C CA  . GLY B 2 46  ? 95.227  141.976 128.353 1.00 93.57  ? 41  GLY B CA  1 
ATOM 1984 C C   . GLY B 2 46  ? 95.692  140.723 127.636 1.00 93.57  ? 41  GLY B C   1 
ATOM 1985 O O   . GLY B 2 46  ? 96.229  139.785 128.228 1.00 93.57  ? 41  GLY B O   1 
ATOM 1986 N N   . ARG B 2 47  ? 95.470  140.710 126.327 1.00 92.98  ? 42  ARG B N   1 
ATOM 1987 C CA  . ARG B 2 47  ? 95.865  139.559 125.526 1.00 92.98  ? 42  ARG B CA  1 
ATOM 1988 C C   . ARG B 2 47  ? 97.384  139.471 125.458 1.00 92.98  ? 42  ARG B C   1 
ATOM 1989 O O   . ARG B 2 47  ? 98.050  140.395 124.981 1.00 92.98  ? 42  ARG B O   1 
ATOM 1990 C CB  . ARG B 2 47  ? 95.272  139.660 124.124 1.00 92.98  ? 42  ARG B CB  1 
ATOM 1991 N N   . ILE B 2 48  ? 97.931  138.357 125.938 1.00 88.90  ? 43  ILE B N   1 
ATOM 1992 C CA  . ILE B 2 48  ? 99.370  138.127 125.970 1.00 88.90  ? 43  ILE B CA  1 
ATOM 1993 C C   . ILE B 2 48  ? 99.715  137.174 124.838 1.00 88.90  ? 43  ILE B C   1 
ATOM 1994 O O   . ILE B 2 48  ? 99.162  136.071 124.755 1.00 88.90  ? 43  ILE B O   1 
ATOM 1995 C CB  . ILE B 2 48  ? 99.830  137.565 127.323 1.00 88.90  ? 43  ILE B CB  1 
ATOM 1996 C CG1 . ILE B 2 48  ? 99.508  138.548 128.448 1.00 88.90  ? 43  ILE B CG1 1 
ATOM 1997 C CG2 . ILE B 2 48  ? 101.315 137.255 127.291 1.00 88.90  ? 43  ILE B CG2 1 
ATOM 1998 C CD1 . ILE B 2 48  ? 100.421 139.752 128.486 1.00 88.90  ? 43  ILE B CD1 1 
ATOM 1999 N N   . GLN B 2 49  ? 100.626 137.597 123.969 1.00 86.28  ? 44  GLN B N   1 
ATOM 2000 C CA  . GLN B 2 49  ? 101.058 136.807 122.821 1.00 86.28  ? 44  GLN B CA  1 
ATOM 2001 C C   . GLN B 2 49  ? 102.580 136.745 122.850 1.00 86.28  ? 44  GLN B C   1 
ATOM 2002 O O   . GLN B 2 49  ? 103.255 137.732 122.540 1.00 86.28  ? 44  GLN B O   1 
ATOM 2003 C CB  . GLN B 2 49  ? 100.546 137.409 121.516 1.00 86.28  ? 44  GLN B CB  1 
ATOM 2004 N N   . MET B 2 50  ? 103.117 135.589 123.219 1.00 82.63  ? 45  MET B N   1 
ATOM 2005 C CA  . MET B 2 50  ? 104.552 135.364 123.267 1.00 82.63  ? 45  MET B CA  1 
ATOM 2006 C C   . MET B 2 50  ? 104.938 134.389 122.165 1.00 82.63  ? 45  MET B C   1 
ATOM 2007 O O   . MET B 2 50  ? 104.168 133.487 121.826 1.00 82.63  ? 45  MET B O   1 
ATOM 2008 C CB  . MET B 2 50  ? 104.976 134.822 124.632 1.00 82.63  ? 45  MET B CB  1 
ATOM 2009 C CG  . MET B 2 50  ? 104.660 135.764 125.784 1.00 82.63  ? 45  MET B CG  1 
ATOM 2010 S SD  . MET B 2 50  ? 105.242 135.172 127.382 1.00 82.63  ? 45  MET B SD  1 
ATOM 2011 C CE  . MET B 2 50  ? 105.141 133.403 127.152 1.00 82.63  ? 45  MET B CE  1 
ATOM 2012 N N   . ARG B 2 51  ? 106.127 134.578 121.605 1.00 76.86  ? 46  ARG B N   1 
ATOM 2013 C CA  . ARG B 2 51  ? 106.570 133.810 120.454 1.00 76.86  ? 46  ARG B CA  1 
ATOM 2014 C C   . ARG B 2 51  ? 107.927 133.186 120.740 1.00 76.86  ? 46  ARG B C   1 
ATOM 2015 O O   . ARG B 2 51  ? 108.663 133.617 121.631 1.00 76.86  ? 46  ARG B O   1 
ATOM 2016 C CB  . ARG B 2 51  ? 106.646 134.685 119.196 1.00 76.86  ? 46  ARG B CB  1 
ATOM 2017 N N   . THR B 2 52  ? 108.247 132.151 119.970 1.00 73.85  ? 47  THR B N   1 
ATOM 2018 C CA  . THR B 2 52  ? 109.547 131.512 120.078 1.00 73.85  ? 47  THR B CA  1 
ATOM 2019 C C   . THR B 2 52  ? 110.655 132.484 119.697 1.00 73.85  ? 47  THR B C   1 
ATOM 2020 O O   . THR B 2 52  ? 110.485 133.336 118.822 1.00 73.85  ? 47  THR B O   1 
ATOM 2021 C CB  . THR B 2 52  ? 109.601 130.269 119.191 1.00 73.85  ? 47  THR B CB  1 
ATOM 2022 O OG1 . THR B 2 52  ? 110.881 129.641 119.324 1.00 73.85  ? 47  THR B OG1 1 
ATOM 2023 C CG2 . THR B 2 52  ? 109.360 130.630 117.735 1.00 73.85  ? 47  THR B CG2 1 
ATOM 2024 N N   . ARG B 2 53  ? 111.777 132.371 120.375 1.00 75.03  ? 48  ARG B N   1 
ATOM 2025 C CA  . ARG B 2 53  ? 112.941 133.198 120.081 1.00 75.03  ? 48  ARG B CA  1 
ATOM 2026 C C   . ARG B 2 53  ? 114.192 132.379 119.821 1.00 75.03  ? 48  ARG B C   1 
ATOM 2027 O O   . ARG B 2 53  ? 115.012 132.768 118.986 1.00 75.03  ? 48  ARG B O   1 
ATOM 2028 C CB  . ARG B 2 53  ? 113.194 134.177 121.224 1.00 75.03  ? 48  ARG B CB  1 
ATOM 2029 C CG  . ARG B 2 53  ? 112.129 135.236 121.364 1.00 75.03  ? 48  ARG B CG  1 
ATOM 2030 C CD  . ARG B 2 53  ? 111.995 136.061 120.101 1.00 75.03  ? 48  ARG B CD  1 
ATOM 2031 N NE  . ARG B 2 53  ? 111.752 137.468 120.404 1.00 75.03  ? 48  ARG B NE  1 
ATOM 2032 C CZ  . ARG B 2 53  ? 110.548 138.025 120.438 1.00 75.03  ? 48  ARG B CZ  1 
ATOM 2033 N NH1 . ARG B 2 53  ? 109.472 137.294 120.187 1.00 75.03  ? 48  ARG B NH1 1 
ATOM 2034 N NH2 . ARG B 2 53  ? 110.418 139.312 120.724 1.00 75.03  ? 48  ARG B NH2 1 
ATOM 2035 N N   . ARG B 2 54  ? 114.362 131.259 120.512 1.00 73.61  ? 49  ARG B N   1 
ATOM 2036 C CA  . ARG B 2 54  ? 115.479 130.360 120.283 1.00 73.61  ? 49  ARG B CA  1 
ATOM 2037 C C   . ARG B 2 54  ? 114.939 128.948 120.126 1.00 73.61  ? 49  ARG B C   1 
ATOM 2038 O O   . ARG B 2 54  ? 113.786 128.662 120.454 1.00 73.61  ? 49  ARG B O   1 
ATOM 2039 C CB  . ARG B 2 54  ? 116.488 130.402 121.432 1.00 73.61  ? 49  ARG B CB  1 
ATOM 2040 C CG  . ARG B 2 54  ? 117.136 131.753 121.655 1.00 73.61  ? 49  ARG B CG  1 
ATOM 2041 C CD  . ARG B 2 54  ? 118.062 132.140 120.530 1.00 73.61  ? 49  ARG B CD  1 
ATOM 2042 N NE  . ARG B 2 54  ? 118.721 133.410 120.809 1.00 73.61  ? 49  ARG B NE  1 
ATOM 2043 C CZ  . ARG B 2 54  ? 119.535 134.032 119.965 1.00 73.61  ? 49  ARG B CZ  1 
ATOM 2044 N NH1 . ARG B 2 54  ? 119.796 133.500 118.780 1.00 73.61  ? 49  ARG B NH1 1 
ATOM 2045 N NH2 . ARG B 2 54  ? 120.088 135.186 120.307 1.00 73.61  ? 49  ARG B NH2 1 
ATOM 2046 N N   . THR B 2 55  ? 115.783 128.065 119.613 1.00 74.43  ? 50  THR B N   1 
ATOM 2047 C CA  . THR B 2 55  ? 115.487 126.643 119.570 1.00 74.43  ? 50  THR B CA  1 
ATOM 2048 C C   . THR B 2 55  ? 116.766 125.872 119.846 1.00 74.43  ? 50  THR B C   1 
ATOM 2049 O O   . THR B 2 55  ? 117.840 126.231 119.353 1.00 74.43  ? 50  THR B O   1 
ATOM 2050 C CB  . THR B 2 55  ? 114.870 126.226 118.225 1.00 74.43  ? 50  THR B CB  1 
ATOM 2051 O OG1 . THR B 2 55  ? 114.505 124.843 118.274 1.00 74.43  ? 50  THR B OG1 1 
ATOM 2052 C CG2 . THR B 2 55  ? 115.835 126.467 117.067 1.00 74.43  ? 50  THR B CG2 1 
ATOM 2053 N N   . LEU B 2 56  ? 116.656 124.835 120.667 1.00 71.08  ? 51  LEU B N   1 
ATOM 2054 C CA  . LEU B 2 56  ? 117.812 124.075 121.126 1.00 71.08  ? 51  LEU B CA  1 
ATOM 2055 C C   . LEU B 2 56  ? 117.644 122.630 120.689 1.00 71.08  ? 51  LEU B C   1 
ATOM 2056 O O   . LEU B 2 56  ? 116.683 121.964 121.084 1.00 71.08  ? 51  LEU B O   1 
ATOM 2057 C CB  . LEU B 2 56  ? 117.963 124.184 122.640 1.00 71.08  ? 51  LEU B CB  1 
ATOM 2058 C CG  . LEU B 2 56  ? 118.116 125.609 123.169 1.00 71.08  ? 51  LEU B CG  1 
ATOM 2059 C CD1 . LEU B 2 56  ? 118.307 125.606 124.669 1.00 71.08  ? 51  LEU B CD1 1 
ATOM 2060 C CD2 . LEU B 2 56  ? 119.273 126.311 122.483 1.00 71.08  ? 51  LEU B CD2 1 
ATOM 2061 N N   . ARG B 2 57  ? 118.577 122.150 119.876 1.00 71.60  ? 52  ARG B N   1 
ATOM 2062 C CA  . ARG B 2 57  ? 118.556 120.793 119.359 1.00 71.60  ? 52  ARG B CA  1 
ATOM 2063 C C   . ARG B 2 57  ? 119.821 120.058 119.773 1.00 71.60  ? 52  ARG B C   1 
ATOM 2064 O O   . ARG B 2 57  ? 120.867 120.662 120.016 1.00 71.60  ? 52  ARG B O   1 
ATOM 2065 C CB  . ARG B 2 57  ? 118.422 120.791 117.833 1.00 71.60  ? 52  ARG B CB  1 
ATOM 2066 N N   . GLY B 2 58  ? 119.718 118.735 119.838 1.00 70.57  ? 53  GLY B N   1 
ATOM 2067 C CA  . GLY B 2 58  ? 120.865 117.922 120.179 1.00 70.57  ? 53  GLY B CA  1 
ATOM 2068 C C   . GLY B 2 58  ? 120.533 116.714 121.024 1.00 70.57  ? 53  GLY B C   1 
ATOM 2069 O O   . GLY B 2 58  ? 121.307 115.754 121.067 1.00 70.57  ? 53  GLY B O   1 
ATOM 2070 N N   . HIS B 2 59  ? 119.388 116.737 121.696 1.00 70.15  ? 54  HIS B N   1 
ATOM 2071 C CA  . HIS B 2 59  ? 118.992 115.591 122.495 1.00 70.15  ? 54  HIS B CA  1 
ATOM 2072 C C   . HIS B 2 59  ? 118.598 114.428 121.593 1.00 70.15  ? 54  HIS B C   1 
ATOM 2073 O O   . HIS B 2 59  ? 118.301 114.596 120.407 1.00 70.15  ? 54  HIS B O   1 
ATOM 2074 C CB  . HIS B 2 59  ? 117.835 115.953 123.424 1.00 70.15  ? 54  HIS B CB  1 
ATOM 2075 C CG  . HIS B 2 59  ? 118.269 116.379 124.789 1.00 70.15  ? 54  HIS B CG  1 
ATOM 2076 N ND1 . HIS B 2 59  ? 119.068 115.597 125.593 1.00 70.15  ? 54  HIS B ND1 1 
ATOM 2077 C CD2 . HIS B 2 59  ? 118.009 117.503 125.496 1.00 70.15  ? 54  HIS B CD2 1 
ATOM 2078 C CE1 . HIS B 2 59  ? 119.288 116.224 126.734 1.00 70.15  ? 54  HIS B CE1 1 
ATOM 2079 N NE2 . HIS B 2 59  ? 118.656 117.383 126.702 1.00 70.15  ? 54  HIS B NE2 1 
ATOM 2080 N N   . LEU B 2 60  ? 118.598 113.232 122.171 1.00 72.64  ? 55  LEU B N   1 
ATOM 2081 C CA  . LEU B 2 60  ? 118.341 112.014 121.416 1.00 72.64  ? 55  LEU B CA  1 
ATOM 2082 C C   . LEU B 2 60  ? 116.930 111.478 121.605 1.00 72.64  ? 55  LEU B C   1 
ATOM 2083 O O   . LEU B 2 60  ? 116.364 110.900 120.675 1.00 72.64  ? 55  LEU B O   1 
ATOM 2084 C CB  . LEU B 2 60  ? 119.347 110.933 121.813 1.00 72.64  ? 55  LEU B CB  1 
ATOM 2085 C CG  . LEU B 2 60  ? 120.781 111.279 121.426 1.00 72.64  ? 55  LEU B CG  1 
ATOM 2086 C CD1 . LEU B 2 60  ? 121.766 110.248 121.956 1.00 72.64  ? 55  LEU B CD1 1 
ATOM 2087 C CD2 . LEU B 2 60  ? 120.893 111.438 119.931 1.00 72.64  ? 55  LEU B CD2 1 
ATOM 2088 N N   . ALA B 2 61  ? 116.352 111.655 122.787 1.00 73.14  ? 56  ALA B N   1 
ATOM 2089 C CA  . ALA B 2 61  ? 115.056 111.080 123.116 1.00 73.14  ? 56  ALA B CA  1 
ATOM 2090 C C   . ALA B 2 61  ? 114.295 112.085 123.976 1.00 73.14  ? 56  ALA B C   1 
ATOM 2091 O O   . ALA B 2 61  ? 114.635 113.272 124.044 1.00 73.14  ? 56  ALA B O   1 
ATOM 2092 C CB  . ALA B 2 61  ? 115.230 109.719 123.800 1.00 73.14  ? 56  ALA B CB  1 
ATOM 2093 N N   . LYS B 2 62  ? 113.237 111.612 124.629 1.00 72.63  ? 57  LYS B N   1 
ATOM 2094 C CA  . LYS B 2 62  ? 112.402 112.465 125.460 1.00 72.63  ? 57  LYS B CA  1 
ATOM 2095 C C   . LYS B 2 62  ? 113.226 113.151 126.545 1.00 72.63  ? 57  LYS B C   1 
ATOM 2096 O O   . LYS B 2 62  ? 114.307 112.695 126.929 1.00 72.63  ? 57  LYS B O   1 
ATOM 2097 C CB  . LYS B 2 62  ? 111.292 111.641 126.107 1.00 72.63  ? 57  LYS B CB  1 
ATOM 2098 C CG  . LYS B 2 62  ? 110.478 110.821 125.125 1.00 72.63  ? 57  LYS B CG  1 
ATOM 2099 C CD  . LYS B 2 62  ? 109.461 109.958 125.849 1.00 72.63  ? 57  LYS B CD  1 
ATOM 2100 C CE  . LYS B 2 62  ? 110.134 108.802 126.568 1.00 72.63  ? 57  LYS B CE  1 
ATOM 2101 N NZ  . LYS B 2 62  ? 110.741 107.833 125.618 1.00 72.63  ? 57  LYS B NZ  1 
ATOM 2102 N N   . ILE B 2 63  ? 112.698 114.264 127.045 1.00 69.72  ? 58  ILE B N   1 
ATOM 2103 C CA  . ILE B 2 63  ? 113.317 115.025 128.125 1.00 69.72  ? 58  ILE B CA  1 
ATOM 2104 C C   . ILE B 2 63  ? 112.307 115.142 129.257 1.00 69.72  ? 58  ILE B C   1 
ATOM 2105 O O   . ILE B 2 63  ? 111.112 115.349 129.013 1.00 69.72  ? 58  ILE B O   1 
ATOM 2106 C CB  . ILE B 2 63  ? 113.792 116.407 127.654 1.00 69.72  ? 58  ILE B CB  1 
ATOM 2107 C CG1 . ILE B 2 63  ? 112.610 117.250 127.201 1.00 69.72  ? 58  ILE B CG1 1 
ATOM 2108 C CG2 . ILE B 2 63  ? 114.800 116.271 126.530 1.00 69.72  ? 58  ILE B CG2 1 
ATOM 2109 C CD1 . ILE B 2 63  ? 112.953 118.675 126.988 1.00 69.72  ? 58  ILE B CD1 1 
ATOM 2110 N N   . TYR B 2 64  ? 112.778 114.985 130.492 1.00 70.32  ? 59  TYR B N   1 
ATOM 2111 C CA  . TYR B 2 64  ? 111.903 114.958 131.654 1.00 70.32  ? 59  TYR B CA  1 
ATOM 2112 C C   . TYR B 2 64  ? 112.230 116.018 132.697 1.00 70.32  ? 59  TYR B C   1 
ATOM 2113 O O   . TYR B 2 64  ? 111.557 116.068 133.730 1.00 70.32  ? 59  TYR B O   1 
ATOM 2114 C CB  . TYR B 2 64  ? 111.950 113.581 132.318 1.00 70.32  ? 59  TYR B CB  1 
ATOM 2115 C CG  . TYR B 2 64  ? 111.142 112.511 131.625 1.00 70.32  ? 59  TYR B CG  1 
ATOM 2116 C CD1 . TYR B 2 64  ? 110.313 112.816 130.556 1.00 70.32  ? 59  TYR B CD1 1 
ATOM 2117 C CD2 . TYR B 2 64  ? 111.200 111.194 132.051 1.00 70.32  ? 59  TYR B CD2 1 
ATOM 2118 C CE1 . TYR B 2 64  ? 109.573 111.834 129.926 1.00 70.32  ? 59  TYR B CE1 1 
ATOM 2119 C CE2 . TYR B 2 64  ? 110.466 110.210 131.432 1.00 70.32  ? 59  TYR B CE2 1 
ATOM 2120 C CZ  . TYR B 2 64  ? 109.654 110.532 130.370 1.00 70.32  ? 59  TYR B CZ  1 
ATOM 2121 O OH  . TYR B 2 64  ? 108.919 109.549 129.750 1.00 70.32  ? 59  TYR B OH  1 
ATOM 2122 N N   . ALA B 2 65  ? 113.227 116.867 132.467 1.00 67.03  ? 60  ALA B N   1 
ATOM 2123 C CA  . ALA B 2 65  ? 113.615 117.825 133.493 1.00 67.03  ? 60  ALA B CA  1 
ATOM 2124 C C   . ALA B 2 65  ? 114.295 119.024 132.849 1.00 67.03  ? 60  ALA B C   1 
ATOM 2125 O O   . ALA B 2 65  ? 114.767 118.965 131.711 1.00 67.03  ? 60  ALA B O   1 
ATOM 2126 C CB  . ALA B 2 65  ? 114.531 117.178 134.535 1.00 67.03  ? 60  ALA B CB  1 
ATOM 2127 N N   . MET B 2 66  ? 114.344 120.117 133.612 1.00 67.16  ? 61  MET B N   1 
ATOM 2128 C CA  . MET B 2 66  ? 114.979 121.365 133.209 1.00 67.16  ? 61  MET B CA  1 
ATOM 2129 C C   . MET B 2 66  ? 115.054 122.305 134.405 1.00 67.16  ? 61  MET B C   1 
ATOM 2130 O O   . MET B 2 66  ? 114.083 122.428 135.157 1.00 67.16  ? 61  MET B O   1 
ATOM 2131 C CB  . MET B 2 66  ? 114.211 121.999 132.048 1.00 67.16  ? 61  MET B CB  1 
ATOM 2132 C CG  . MET B 2 66  ? 114.798 123.278 131.485 1.00 67.16  ? 61  MET B CG  1 
ATOM 2133 S SD  . MET B 2 66  ? 114.364 124.743 132.432 1.00 67.16  ? 61  MET B SD  1 
ATOM 2134 C CE  . MET B 2 66  ? 112.641 124.896 131.984 1.00 67.16  ? 61  MET B CE  1 
ATOM 2135 N N   . HIS B 2 67  ? 116.189 122.974 134.597 1.00 64.70  ? 62  HIS B N   1 
ATOM 2136 C CA  . HIS B 2 67  ? 116.351 123.889 135.720 1.00 64.70  ? 62  HIS B CA  1 
ATOM 2137 C C   . HIS B 2 67  ? 117.290 125.023 135.345 1.00 64.70  ? 62  HIS B C   1 
ATOM 2138 O O   . HIS B 2 67  ? 118.426 124.782 134.930 1.00 64.70  ? 62  HIS B O   1 
ATOM 2139 C CB  . HIS B 2 67  ? 116.886 123.162 136.954 1.00 64.70  ? 62  HIS B CB  1 
ATOM 2140 C CG  . HIS B 2 67  ? 116.625 123.884 138.239 1.00 64.70  ? 62  HIS B CG  1 
ATOM 2141 N ND1 . HIS B 2 67  ? 117.424 123.735 139.352 1.00 64.70  ? 62  HIS B ND1 1 
ATOM 2142 C CD2 . HIS B 2 67  ? 115.651 124.754 138.588 1.00 64.70  ? 62  HIS B CD2 1 
ATOM 2143 C CE1 . HIS B 2 67  ? 116.954 124.487 140.330 1.00 64.70  ? 62  HIS B CE1 1 
ATOM 2144 N NE2 . HIS B 2 67  ? 115.878 125.114 139.893 1.00 64.70  ? 62  HIS B NE2 1 
ATOM 2145 N N   . TRP B 2 68  ? 116.811 126.254 135.496 1.00 67.37  ? 63  TRP B N   1 
ATOM 2146 C CA  . TRP B 2 68  ? 117.630 127.436 135.289 1.00 67.37  ? 63  TRP B CA  1 
ATOM 2147 C C   . TRP B 2 68  ? 118.584 127.635 136.458 1.00 67.37  ? 63  TRP B C   1 
ATOM 2148 O O   . TRP B 2 68  ? 118.299 127.243 137.592 1.00 67.37  ? 63  TRP B O   1 
ATOM 2149 C CB  . TRP B 2 68  ? 116.752 128.676 135.135 1.00 67.37  ? 63  TRP B CB  1 
ATOM 2150 C CG  . TRP B 2 68  ? 116.293 128.939 133.740 1.00 67.37  ? 63  TRP B CG  1 
ATOM 2151 C CD1 . TRP B 2 68  ? 115.085 128.624 133.207 1.00 67.37  ? 63  TRP B CD1 1 
ATOM 2152 C CD2 . TRP B 2 68  ? 117.029 129.598 132.706 1.00 67.37  ? 63  TRP B CD2 1 
ATOM 2153 N NE1 . TRP B 2 68  ? 115.023 129.032 131.898 1.00 67.37  ? 63  TRP B NE1 1 
ATOM 2154 C CE2 . TRP B 2 68  ? 116.206 129.636 131.568 1.00 67.37  ? 63  TRP B CE2 1 
ATOM 2155 C CE3 . TRP B 2 68  ? 118.308 130.154 132.632 1.00 67.37  ? 63  TRP B CE3 1 
ATOM 2156 C CZ2 . TRP B 2 68  ? 116.618 130.202 130.369 1.00 67.37  ? 63  TRP B CZ2 1 
ATOM 2157 C CZ3 . TRP B 2 68  ? 118.715 130.720 131.441 1.00 67.37  ? 63  TRP B CZ3 1 
ATOM 2158 C CH2 . TRP B 2 68  ? 117.872 130.740 130.325 1.00 67.37  ? 63  TRP B CH2 1 
ATOM 2159 N N   . GLY B 2 69  ? 119.723 128.252 136.174 1.00 70.55  ? 64  GLY B N   1 
ATOM 2160 C CA  . GLY B 2 69  ? 120.689 128.575 137.198 1.00 70.55  ? 64  GLY B CA  1 
ATOM 2161 C C   . GLY B 2 69  ? 120.333 129.861 137.912 1.00 70.55  ? 64  GLY B C   1 
ATOM 2162 O O   . GLY B 2 69  ? 119.240 130.409 137.774 1.00 70.55  ? 64  GLY B O   1 
ATOM 2163 N N   . THR B 2 70  ? 121.288 130.350 138.698 1.00 72.19  ? 65  THR B N   1 
ATOM 2164 C CA  . THR B 2 70  ? 121.108 131.614 139.396 1.00 72.19  ? 65  THR B CA  1 
ATOM 2165 C C   . THR B 2 70  ? 121.683 132.804 138.640 1.00 72.19  ? 65  THR B C   1 
ATOM 2166 O O   . THR B 2 70  ? 121.463 133.944 139.058 1.00 72.19  ? 65  THR B O   1 
ATOM 2167 C CB  . THR B 2 70  ? 121.738 131.548 140.788 1.00 72.19  ? 65  THR B CB  1 
ATOM 2168 O OG1 . THR B 2 70  ? 123.118 131.185 140.675 1.00 72.19  ? 65  THR B OG1 1 
ATOM 2169 C CG2 . THR B 2 70  ? 121.015 130.528 141.645 1.00 72.19  ? 65  THR B CG2 1 
ATOM 2170 N N   . ASP B 2 71  ? 122.409 132.573 137.549 1.00 74.34  ? 66  ASP B N   1 
ATOM 2171 C CA  . ASP B 2 71  ? 122.928 133.656 136.725 1.00 74.34  ? 66  ASP B CA  1 
ATOM 2172 C C   . ASP B 2 71  ? 122.028 133.988 135.542 1.00 74.34  ? 66  ASP B C   1 
ATOM 2173 O O   . ASP B 2 71  ? 122.360 134.885 134.762 1.00 74.34  ? 66  ASP B O   1 
ATOM 2174 C CB  . ASP B 2 71  ? 124.341 133.316 136.236 1.00 74.34  ? 66  ASP B CB  1 
ATOM 2175 C CG  . ASP B 2 71  ? 124.381 132.082 135.350 1.00 74.34  ? 66  ASP B CG  1 
ATOM 2176 O OD1 . ASP B 2 71  ? 123.324 131.450 135.135 1.00 74.34  ? 66  ASP B OD1 1 
ATOM 2177 O OD2 . ASP B 2 71  ? 125.479 131.743 134.863 1.00 74.34  ? 66  ASP B OD2 1 
ATOM 2178 N N   . SER B 2 72  ? 120.911 133.280 135.390 1.00 72.34  ? 67  SER B N   1 
ATOM 2179 C CA  . SER B 2 72  ? 119.906 133.540 134.362 1.00 72.34  ? 67  SER B CA  1 
ATOM 2180 C C   . SER B 2 72  ? 120.450 133.403 132.947 1.00 72.34  ? 67  SER B C   1 
ATOM 2181 O O   . SER B 2 72  ? 119.880 133.967 132.011 1.00 72.34  ? 67  SER B O   1 
ATOM 2182 C CB  . SER B 2 72  ? 119.273 134.923 134.542 1.00 72.34  ? 67  SER B CB  1 
ATOM 2183 O OG  . SER B 2 72  ? 118.711 135.060 135.833 1.00 72.34  ? 67  SER B OG  1 
ATOM 2184 N N   . ARG B 2 73  ? 121.537 132.661 132.751 1.00 71.13  ? 68  ARG B N   1 
ATOM 2185 C CA  . ARG B 2 73  ? 122.062 132.509 131.402 1.00 71.13  ? 68  ARG B CA  1 
ATOM 2186 C C   . ARG B 2 73  ? 122.405 131.057 131.092 1.00 71.13  ? 68  ARG B C   1 
ATOM 2187 O O   . ARG B 2 73  ? 122.397 130.650 129.926 1.00 71.13  ? 68  ARG B O   1 
ATOM 2188 C CB  . ARG B 2 73  ? 123.277 133.424 131.210 1.00 71.13  ? 68  ARG B CB  1 
ATOM 2189 C CG  . ARG B 2 73  ? 123.858 133.426 129.805 1.00 71.13  ? 68  ARG B CG  1 
ATOM 2190 C CD  . ARG B 2 73  ? 124.998 134.426 129.671 1.00 71.13  ? 68  ARG B CD  1 
ATOM 2191 N NE  . ARG B 2 73  ? 125.580 134.406 128.333 1.00 71.13  ? 68  ARG B NE  1 
ATOM 2192 C CZ  . ARG B 2 73  ? 126.573 135.191 127.935 1.00 71.13  ? 68  ARG B CZ  1 
ATOM 2193 N NH1 . ARG B 2 73  ? 127.095 136.079 128.768 1.00 71.13  ? 68  ARG B NH1 1 
ATOM 2194 N NH2 . ARG B 2 73  ? 127.035 135.101 126.696 1.00 71.13  ? 68  ARG B NH2 1 
ATOM 2195 N N   . LEU B 2 74  ? 122.690 130.264 132.116 1.00 67.63  ? 69  LEU B N   1 
ATOM 2196 C CA  . LEU B 2 74  ? 123.031 128.860 131.943 1.00 67.63  ? 69  LEU B CA  1 
ATOM 2197 C C   . LEU B 2 74  ? 121.814 127.979 132.212 1.00 67.63  ? 69  LEU B C   1 
ATOM 2198 O O   . LEU B 2 74  ? 120.842 128.399 132.842 1.00 67.63  ? 69  LEU B O   1 
ATOM 2199 C CB  . LEU B 2 74  ? 124.184 128.471 132.868 1.00 67.63  ? 69  LEU B CB  1 
ATOM 2200 C CG  . LEU B 2 74  ? 125.552 129.055 132.525 1.00 67.63  ? 69  LEU B CG  1 
ATOM 2201 C CD1 . LEU B 2 74  ? 126.557 128.737 133.609 1.00 67.63  ? 69  LEU B CD1 1 
ATOM 2202 C CD2 . LEU B 2 74  ? 126.032 128.515 131.198 1.00 67.63  ? 69  LEU B CD2 1 
ATOM 2203 N N   . LEU B 2 75  ? 121.885 126.740 131.731 1.00 67.68  ? 70  LEU B N   1 
ATOM 2204 C CA  . LEU B 2 75  ? 120.741 125.839 131.771 1.00 67.68  ? 70  LEU B CA  1 
ATOM 2205 C C   . LEU B 2 75  ? 121.230 124.399 131.830 1.00 67.68  ? 70  LEU B C   1 
ATOM 2206 O O   . LEU B 2 75  ? 122.340 124.089 131.389 1.00 67.68  ? 70  LEU B O   1 
ATOM 2207 C CB  . LEU B 2 75  ? 119.849 126.054 130.548 1.00 67.68  ? 70  LEU B CB  1 
ATOM 2208 C CG  . LEU B 2 75  ? 118.495 125.367 130.490 1.00 67.68  ? 70  LEU B CG  1 
ATOM 2209 C CD1 . LEU B 2 75  ? 117.584 125.950 131.549 1.00 67.68  ? 70  LEU B CD1 1 
ATOM 2210 C CD2 . LEU B 2 75  ? 117.896 125.535 129.114 1.00 67.68  ? 70  LEU B CD2 1 
ATOM 2211 N N   . VAL B 2 76  ? 120.394 123.520 132.382 1.00 65.84  ? 71  VAL B N   1 
ATOM 2212 C CA  . VAL B 2 76  ? 120.694 122.097 132.500 1.00 65.84  ? 71  VAL B CA  1 
ATOM 2213 C C   . VAL B 2 76  ? 119.448 121.301 132.135 1.00 65.84  ? 71  VAL B C   1 
ATOM 2214 O O   . VAL B 2 76  ? 118.324 121.713 132.445 1.00 65.84  ? 71  VAL B O   1 
ATOM 2215 C CB  . VAL B 2 76  ? 121.192 121.736 133.914 1.00 65.84  ? 71  VAL B CB  1 
ATOM 2216 C CG1 . VAL B 2 76  ? 120.113 121.980 134.949 1.00 65.84  ? 71  VAL B CG1 1 
ATOM 2217 C CG2 . VAL B 2 76  ? 121.663 120.294 133.961 1.00 65.84  ? 71  VAL B CG2 1 
ATOM 2218 N N   . SER B 2 77  ? 119.641 120.173 131.452 1.00 68.08  ? 72  SER B N   1 
ATOM 2219 C CA  . SER B 2 77  ? 118.533 119.350 130.988 1.00 68.08  ? 72  SER B CA  1 
ATOM 2220 C C   . SER B 2 77  ? 118.873 117.875 131.153 1.00 68.08  ? 72  SER B C   1 
ATOM 2221 O O   . SER B 2 77  ? 120.041 117.501 131.281 1.00 68.08  ? 72  SER B O   1 
ATOM 2222 C CB  . SER B 2 77  ? 118.191 119.640 129.526 1.00 68.08  ? 72  SER B CB  1 
ATOM 2223 O OG  . SER B 2 77  ? 119.161 119.088 128.657 1.00 68.08  ? 72  SER B OG  1 
ATOM 2224 N N   . ALA B 2 78  ? 117.834 117.040 131.146 1.00 67.27  ? 73  ALA B N   1 
ATOM 2225 C CA  . ALA B 2 78  ? 117.966 115.595 131.272 1.00 67.27  ? 73  ALA B CA  1 
ATOM 2226 C C   . ALA B 2 78  ? 117.199 114.915 130.152 1.00 67.27  ? 73  ALA B C   1 
ATOM 2227 O O   . ALA B 2 78  ? 116.227 115.468 129.632 1.00 67.27  ? 73  ALA B O   1 
ATOM 2228 C CB  . ALA B 2 78  ? 117.440 115.093 132.608 1.00 67.27  ? 73  ALA B CB  1 
ATOM 2229 N N   . SER B 2 79  ? 117.636 113.715 129.787 1.00 69.34  ? 74  SER B N   1 
ATOM 2230 C CA  . SER B 2 79  ? 116.998 112.970 128.716 1.00 69.34  ? 74  SER B CA  1 
ATOM 2231 C C   . SER B 2 79  ? 117.109 111.481 128.990 1.00 69.34  ? 74  SER B C   1 
ATOM 2232 O O   . SER B 2 79  ? 117.940 111.030 129.779 1.00 69.34  ? 74  SER B O   1 
ATOM 2233 C CB  . SER B 2 79  ? 117.612 113.302 127.354 1.00 69.34  ? 74  SER B CB  1 
ATOM 2234 O OG  . SER B 2 79  ? 117.002 112.545 126.322 1.00 69.34  ? 74  SER B OG  1 
ATOM 2235 N N   . GLN B 2 80  ? 116.251 110.720 128.314 1.00 71.38  ? 75  GLN B N   1 
ATOM 2236 C CA  . GLN B 2 80  ? 116.192 109.280 128.518 1.00 71.38  ? 75  GLN B CA  1 
ATOM 2237 C C   . GLN B 2 80  ? 117.450 108.572 128.037 1.00 71.38  ? 75  GLN B C   1 
ATOM 2238 O O   . GLN B 2 80  ? 117.717 107.447 128.471 1.00 71.38  ? 75  GLN B O   1 
ATOM 2239 C CB  . GLN B 2 80  ? 114.971 108.708 127.801 1.00 71.38  ? 75  GLN B CB  1 
ATOM 2240 C CG  . GLN B 2 80  ? 113.651 109.196 128.362 1.00 71.38  ? 75  GLN B CG  1 
ATOM 2241 C CD  . GLN B 2 80  ? 113.442 108.785 129.799 1.00 71.38  ? 75  GLN B CD  1 
ATOM 2242 O OE1 . GLN B 2 80  ? 113.486 109.613 130.706 1.00 71.38  ? 75  GLN B OE1 1 
ATOM 2243 N NE2 . GLN B 2 80  ? 113.192 107.505 130.014 1.00 71.38  ? 75  GLN B NE2 1 
ATOM 2244 N N   . ASP B 2 81  ? 118.226 109.199 127.152 1.00 71.78  ? 76  ASP B N   1 
ATOM 2245 C CA  . ASP B 2 81  ? 119.440 108.569 126.649 1.00 71.78  ? 76  ASP B CA  1 
ATOM 2246 C C   . ASP B 2 81  ? 120.538 108.504 127.702 1.00 71.78  ? 76  ASP B C   1 
ATOM 2247 O O   . ASP B 2 81  ? 121.520 107.781 127.512 1.00 71.78  ? 76  ASP B O   1 
ATOM 2248 C CB  . ASP B 2 81  ? 119.945 109.314 125.414 1.00 71.78  ? 76  ASP B CB  1 
ATOM 2249 C CG  . ASP B 2 81  ? 120.226 110.780 125.689 1.00 71.78  ? 76  ASP B CG  1 
ATOM 2250 O OD1 . ASP B 2 81  ? 119.934 111.247 126.809 1.00 71.78  ? 76  ASP B OD1 1 
ATOM 2251 O OD2 . ASP B 2 81  ? 120.742 111.467 124.784 1.00 71.78  ? 76  ASP B OD2 1 
ATOM 2252 N N   . GLY B 2 82  ? 120.394 109.241 128.799 1.00 71.69  ? 77  GLY B N   1 
ATOM 2253 C CA  . GLY B 2 82  ? 121.398 109.250 129.841 1.00 71.69  ? 77  GLY B CA  1 
ATOM 2254 C C   . GLY B 2 82  ? 122.438 110.329 129.639 1.00 71.69  ? 77  GLY B C   1 
ATOM 2255 O O   . GLY B 2 82  ? 123.638 110.043 129.641 1.00 71.69  ? 77  GLY B O   1 
ATOM 2256 N N   . LYS B 2 83  ? 121.998 111.573 129.466 1.00 68.57  ? 78  LYS B N   1 
ATOM 2257 C CA  . LYS B 2 83  ? 122.916 112.664 129.183 1.00 68.57  ? 78  LYS B CA  1 
ATOM 2258 C C   . LYS B 2 83  ? 122.395 113.959 129.781 1.00 68.57  ? 78  LYS B C   1 
ATOM 2259 O O   . LYS B 2 83  ? 121.228 114.311 129.602 1.00 68.57  ? 78  LYS B O   1 
ATOM 2260 C CB  . LYS B 2 83  ? 123.122 112.838 127.677 1.00 68.57  ? 78  LYS B CB  1 
ATOM 2261 C CG  . LYS B 2 83  ? 124.199 111.952 127.101 1.00 68.57  ? 78  LYS B CG  1 
ATOM 2262 C CD  . LYS B 2 83  ? 124.636 112.440 125.741 1.00 68.57  ? 78  LYS B CD  1 
ATOM 2263 C CE  . LYS B 2 83  ? 125.879 111.712 125.283 1.00 68.57  ? 78  LYS B CE  1 
ATOM 2264 N NZ  . LYS B 2 83  ? 125.622 110.263 125.060 1.00 68.57  ? 78  LYS B NZ  1 
ATOM 2265 N N   . LEU B 2 84  ? 123.272 114.662 130.489 1.00 66.34  ? 79  LEU B N   1 
ATOM 2266 C CA  . LEU B 2 84  ? 123.026 116.021 130.942 1.00 66.34  ? 79  LEU B CA  1 
ATOM 2267 C C   . LEU B 2 84  ? 123.828 116.982 130.080 1.00 66.34  ? 79  LEU B C   1 
ATOM 2268 O O   . LEU B 2 84  ? 125.049 116.839 129.956 1.00 66.34  ? 79  LEU B O   1 
ATOM 2269 C CB  . LEU B 2 84  ? 123.403 116.195 132.413 1.00 66.34  ? 79  LEU B CB  1 
ATOM 2270 C CG  . LEU B 2 84  ? 122.352 115.877 133.471 1.00 66.34  ? 79  LEU B CG  1 
ATOM 2271 C CD1 . LEU B 2 84  ? 122.086 114.393 133.538 1.00 66.34  ? 79  LEU B CD1 1 
ATOM 2272 C CD2 . LEU B 2 84  ? 122.802 116.395 134.820 1.00 66.34  ? 79  LEU B CD2 1 
ATOM 2273 N N   . ILE B 2 85  ? 123.146 117.955 129.488 1.00 68.07  ? 80  ILE B N   1 
ATOM 2274 C CA  . ILE B 2 85  ? 123.769 118.958 128.635 1.00 68.07  ? 80  ILE B CA  1 
ATOM 2275 C C   . ILE B 2 85  ? 123.598 120.313 129.300 1.00 68.07  ? 80  ILE B C   1 
ATOM 2276 O O   . ILE B 2 85  ? 122.487 120.671 129.711 1.00 68.07  ? 80  ILE B O   1 
ATOM 2277 C CB  . ILE B 2 85  ? 123.160 118.960 127.224 1.00 68.07  ? 80  ILE B CB  1 
ATOM 2278 C CG1 . ILE B 2 85  ? 123.432 117.632 126.526 1.00 68.07  ? 80  ILE B CG1 1 
ATOM 2279 C CG2 . ILE B 2 85  ? 123.722 120.105 126.402 1.00 68.07  ? 80  ILE B CG2 1 
ATOM 2280 C CD1 . ILE B 2 85  ? 122.667 117.461 125.239 1.00 68.07  ? 80  ILE B CD1 1 
ATOM 2281 N N   . ILE B 2 86  ? 124.688 121.062 129.408 1.00 67.67  ? 81  ILE B N   1 
ATOM 2282 C CA  . ILE B 2 86  ? 124.672 122.396 129.991 1.00 67.67  ? 81  ILE B CA  1 
ATOM 2283 C C   . ILE B 2 86  ? 124.762 123.391 128.844 1.00 67.67  ? 81  ILE B C   1 
ATOM 2284 O O   . ILE B 2 86  ? 125.786 123.468 128.153 1.00 67.67  ? 81  ILE B O   1 
ATOM 2285 C CB  . ILE B 2 86  ? 125.811 122.597 130.996 1.00 67.67  ? 81  ILE B CB  1 
ATOM 2286 C CG1 . ILE B 2 86  ? 125.512 121.855 132.294 1.00 67.67  ? 81  ILE B CG1 1 
ATOM 2287 C CG2 . ILE B 2 86  ? 126.010 124.069 131.285 1.00 67.67  ? 81  ILE B CG2 1 
ATOM 2288 C CD1 . ILE B 2 86  ? 126.622 121.941 133.300 1.00 67.67  ? 81  ILE B CD1 1 
ATOM 2289 N N   . TRP B 2 87  ? 123.692 124.148 128.633 1.00 70.86  ? 82  TRP B N   1 
ATOM 2290 C CA  . TRP B 2 87  ? 123.580 125.069 127.513 1.00 70.86  ? 82  TRP B CA  1 
ATOM 2291 C C   . TRP B 2 87  ? 124.000 126.475 127.914 1.00 70.86  ? 82  TRP B C   1 
ATOM 2292 O O   . TRP B 2 87  ? 124.208 126.782 129.090 1.00 70.86  ? 82  TRP B O   1 
ATOM 2293 C CB  . TRP B 2 87  ? 122.148 125.105 126.974 1.00 70.86  ? 82  TRP B CB  1 
ATOM 2294 C CG  . TRP B 2 87  ? 121.623 123.792 126.502 1.00 70.86  ? 82  TRP B CG  1 
ATOM 2295 C CD1 . TRP B 2 87  ? 121.211 122.749 127.272 1.00 70.86  ? 82  TRP B CD1 1 
ATOM 2296 C CD2 . TRP B 2 87  ? 121.449 123.381 125.143 1.00 70.86  ? 82  TRP B CD2 1 
ATOM 2297 N NE1 . TRP B 2 87  ? 120.791 121.713 126.478 1.00 70.86  ? 82  TRP B NE1 1 
ATOM 2298 C CE2 . TRP B 2 87  ? 120.931 122.077 125.166 1.00 70.86  ? 82  TRP B CE2 1 
ATOM 2299 C CE3 . TRP B 2 87  ? 121.689 123.989 123.910 1.00 70.86  ? 82  TRP B CE3 1 
ATOM 2300 C CZ2 . TRP B 2 87  ? 120.646 121.368 124.007 1.00 70.86  ? 82  TRP B CZ2 1 
ATOM 2301 C CZ3 . TRP B 2 87  ? 121.404 123.285 122.759 1.00 70.86  ? 82  TRP B CZ3 1 
ATOM 2302 C CH2 . TRP B 2 87  ? 120.887 121.989 122.815 1.00 70.86  ? 82  TRP B CH2 1 
ATOM 2303 N N   . ASP B 2 88  ? 124.126 127.330 126.906 1.00 73.64  ? 83  ASP B N   1 
ATOM 2304 C CA  . ASP B 2 88  ? 124.293 128.768 127.079 1.00 73.64  ? 83  ASP B CA  1 
ATOM 2305 C C   . ASP B 2 88  ? 123.232 129.429 126.212 1.00 73.64  ? 83  ASP B C   1 
ATOM 2306 O O   . ASP B 2 88  ? 123.370 129.480 124.986 1.00 73.64  ? 83  ASP B O   1 
ATOM 2307 C CB  . ASP B 2 88  ? 125.700 129.214 126.690 1.00 73.64  ? 83  ASP B CB  1 
ATOM 2308 C CG  . ASP B 2 88  ? 125.844 130.720 126.646 1.00 73.64  ? 83  ASP B CG  1 
ATOM 2309 O OD1 . ASP B 2 88  ? 125.181 131.409 127.447 1.00 73.64  ? 83  ASP B OD1 1 
ATOM 2310 O OD2 . ASP B 2 88  ? 126.627 131.218 125.811 1.00 73.64  ? 83  ASP B OD2 1 
ATOM 2311 N N   . SER B 2 89  ? 122.174 129.934 126.852 1.00 73.29  ? 84  SER B N   1 
ATOM 2312 C CA  . SER B 2 89  ? 120.958 130.282 126.124 1.00 73.29  ? 84  SER B CA  1 
ATOM 2313 C C   . SER B 2 89  ? 121.181 131.398 125.114 1.00 73.29  ? 84  SER B C   1 
ATOM 2314 O O   . SER B 2 89  ? 120.526 131.418 124.065 1.00 73.29  ? 84  SER B O   1 
ATOM 2315 C CB  . SER B 2 89  ? 119.860 130.678 127.107 1.00 73.29  ? 84  SER B CB  1 
ATOM 2316 O OG  . SER B 2 89  ? 118.874 131.467 126.471 1.00 73.29  ? 84  SER B OG  1 
ATOM 2317 N N   . TYR B 2 90  ? 122.084 132.337 125.402 1.00 72.92  ? 85  TYR B N   1 
ATOM 2318 C CA  . TYR B 2 90  ? 122.260 133.483 124.515 1.00 72.92  ? 85  TYR B CA  1 
ATOM 2319 C C   . TYR B 2 90  ? 122.814 133.061 123.160 1.00 72.92  ? 85  TYR B C   1 
ATOM 2320 O O   . TYR B 2 90  ? 122.256 133.411 122.114 1.00 72.92  ? 85  TYR B O   1 
ATOM 2321 C CB  . TYR B 2 90  ? 123.171 134.520 125.166 1.00 72.92  ? 85  TYR B CB  1 
ATOM 2322 C CG  . TYR B 2 90  ? 122.543 135.270 126.317 1.00 72.92  ? 85  TYR B CG  1 
ATOM 2323 C CD1 . TYR B 2 90  ? 121.184 135.196 126.566 1.00 72.92  ? 85  TYR B CD1 1 
ATOM 2324 C CD2 . TYR B 2 90  ? 123.312 136.071 127.142 1.00 72.92  ? 85  TYR B CD2 1 
ATOM 2325 C CE1 . TYR B 2 90  ? 120.615 135.888 127.617 1.00 72.92  ? 85  TYR B CE1 1 
ATOM 2326 C CE2 . TYR B 2 90  ? 122.755 136.762 128.191 1.00 72.92  ? 85  TYR B CE2 1 
ATOM 2327 C CZ  . TYR B 2 90  ? 121.409 136.671 128.425 1.00 72.92  ? 85  TYR B CZ  1 
ATOM 2328 O OH  . TYR B 2 90  ? 120.859 137.368 129.473 1.00 72.92  ? 85  TYR B OH  1 
ATOM 2329 N N   . THR B 2 91  ? 123.906 132.303 123.155 1.00 74.13  ? 86  THR B N   1 
ATOM 2330 C CA  . THR B 2 91  ? 124.577 131.920 121.923 1.00 74.13  ? 86  THR B CA  1 
ATOM 2331 C C   . THR B 2 91  ? 124.264 130.498 121.482 1.00 74.13  ? 86  THR B C   1 
ATOM 2332 O O   . THR B 2 91  ? 124.781 130.058 120.451 1.00 74.13  ? 86  THR B O   1 
ATOM 2333 C CB  . THR B 2 91  ? 126.089 132.087 122.076 1.00 74.13  ? 86  THR B CB  1 
ATOM 2334 O OG1 . THR B 2 91  ? 126.563 131.212 123.105 1.00 74.13  ? 86  THR B OG1 1 
ATOM 2335 C CG2 . THR B 2 91  ? 126.431 133.520 122.441 1.00 74.13  ? 86  THR B CG2 1 
ATOM 2336 N N   . THR B 2 92  ? 123.441 129.773 122.237 1.00 74.49  ? 87  THR B N   1 
ATOM 2337 C CA  . THR B 2 92  ? 123.029 128.405 121.928 1.00 74.49  ? 87  THR B CA  1 
ATOM 2338 C C   . THR B 2 92  ? 124.207 127.450 121.760 1.00 74.49  ? 87  THR B C   1 
ATOM 2339 O O   . THR B 2 92  ? 124.081 126.423 121.089 1.00 74.49  ? 87  THR B O   1 
ATOM 2340 C CB  . THR B 2 92  ? 122.140 128.353 120.681 1.00 74.49  ? 87  THR B CB  1 
ATOM 2341 O OG1 . THR B 2 92  ? 122.945 128.528 119.509 1.00 74.49  ? 87  THR B OG1 1 
ATOM 2342 C CG2 . THR B 2 92  ? 121.081 129.439 120.735 1.00 74.49  ? 87  THR B CG2 1 
ATOM 2343 N N   . ASN B 2 93  ? 125.356 127.757 122.354 1.00 76.81  ? 88  ASN B N   1 
ATOM 2344 C CA  . ASN B 2 93  ? 126.460 126.813 122.323 1.00 76.81  ? 88  ASN B CA  1 
ATOM 2345 C C   . ASN B 2 93  ? 126.224 125.694 123.334 1.00 76.81  ? 88  ASN B C   1 
ATOM 2346 O O   . ASN B 2 93  ? 125.191 125.631 124.008 1.00 76.81  ? 88  ASN B O   1 
ATOM 2347 C CB  . ASN B 2 93  ? 127.785 127.513 122.619 1.00 76.81  ? 88  ASN B CB  1 
ATOM 2348 C CG  . ASN B 2 93  ? 128.148 128.539 121.574 1.00 76.81  ? 88  ASN B CG  1 
ATOM 2349 O OD1 . ASN B 2 93  ? 128.203 129.733 121.857 1.00 76.81  ? 88  ASN B OD1 1 
ATOM 2350 N ND2 . ASN B 2 93  ? 128.401 128.078 120.355 1.00 76.81  ? 88  ASN B ND2 1 
ATOM 2351 N N   . LYS B 2 94  ? 127.202 124.802 123.440 1.00 74.93  ? 89  LYS B N   1 
ATOM 2352 C CA  . LYS B 2 94  ? 127.172 123.722 124.415 1.00 74.93  ? 89  LYS B CA  1 
ATOM 2353 C C   . LYS B 2 94  ? 128.440 123.776 125.253 1.00 74.93  ? 89  LYS B C   1 
ATOM 2354 O O   . LYS B 2 94  ? 129.546 123.862 124.710 1.00 74.93  ? 89  LYS B O   1 
ATOM 2355 C CB  . LYS B 2 94  ? 127.027 122.368 123.725 1.00 74.93  ? 89  LYS B CB  1 
ATOM 2356 C CG  . LYS B 2 94  ? 125.595 122.040 123.374 1.00 74.93  ? 89  LYS B CG  1 
ATOM 2357 C CD  . LYS B 2 94  ? 125.453 120.641 122.831 1.00 74.93  ? 89  LYS B CD  1 
ATOM 2358 C CE  . LYS B 2 94  ? 125.511 120.643 121.323 1.00 74.93  ? 89  LYS B CE  1 
ATOM 2359 N NZ  . LYS B 2 94  ? 124.307 121.287 120.736 1.00 74.93  ? 89  LYS B NZ  1 
ATOM 2360 N N   . VAL B 2 95  ? 128.277 123.725 126.571 1.00 69.05  ? 90  VAL B N   1 
ATOM 2361 C CA  . VAL B 2 95  ? 129.365 123.986 127.499 1.00 69.05  ? 90  VAL B CA  1 
ATOM 2362 C C   . VAL B 2 95  ? 129.896 122.702 128.124 1.00 69.05  ? 90  VAL B C   1 
ATOM 2363 O O   . VAL B 2 95  ? 131.071 122.623 128.485 1.00 69.05  ? 90  VAL B O   1 
ATOM 2364 C CB  . VAL B 2 95  ? 128.891 124.985 128.573 1.00 69.05  ? 90  VAL B CB  1 
ATOM 2365 C CG1 . VAL B 2 95  ? 129.961 125.214 129.627 1.00 69.05  ? 90  VAL B CG1 1 
ATOM 2366 C CG2 . VAL B 2 95  ? 128.489 126.290 127.927 1.00 69.05  ? 90  VAL B CG2 1 
ATOM 2367 N N   . HIS B 2 96  ? 129.060 121.675 128.225 1.00 68.87  ? 91  HIS B N   1 
ATOM 2368 C CA  . HIS B 2 96  ? 129.451 120.424 128.855 1.00 68.87  ? 91  HIS B CA  1 
ATOM 2369 C C   . HIS B 2 96  ? 128.565 119.305 128.331 1.00 68.87  ? 91  HIS B C   1 
ATOM 2370 O O   . HIS B 2 96  ? 127.530 119.542 127.705 1.00 68.87  ? 91  HIS B O   1 
ATOM 2371 C CB  . HIS B 2 96  ? 129.344 120.504 130.379 1.00 68.87  ? 91  HIS B CB  1 
ATOM 2372 C CG  . HIS B 2 96  ? 130.520 121.146 131.045 1.00 68.87  ? 91  HIS B CG  1 
ATOM 2373 N ND1 . HIS B 2 96  ? 130.435 122.354 131.700 1.00 68.87  ? 91  HIS B ND1 1 
ATOM 2374 C CD2 . HIS B 2 96  ? 131.801 120.735 131.179 1.00 68.87  ? 91  HIS B CD2 1 
ATOM 2375 C CE1 . HIS B 2 96  ? 131.616 122.665 132.201 1.00 68.87  ? 91  HIS B CE1 1 
ATOM 2376 N NE2 . HIS B 2 96  ? 132.464 121.699 131.898 1.00 68.87  ? 91  HIS B NE2 1 
ATOM 2377 N N   . ALA B 2 97  ? 128.988 118.074 128.598 1.00 67.51  ? 92  ALA B N   1 
ATOM 2378 C CA  . ALA B 2 97  ? 128.207 116.891 128.251 1.00 67.51  ? 92  ALA B CA  1 
ATOM 2379 C C   . ALA B 2 97  ? 128.599 115.796 129.231 1.00 67.51  ? 92  ALA B C   1 
ATOM 2380 O O   . ALA B 2 97  ? 129.736 115.319 129.207 1.00 67.51  ? 92  ALA B O   1 
ATOM 2381 C CB  . ALA B 2 97  ? 128.457 116.460 126.812 1.00 67.51  ? 92  ALA B CB  1 
ATOM 2382 N N   . ILE B 2 98  ? 127.664 115.404 130.083 1.00 65.72  ? 93  ILE B N   1 
ATOM 2383 C CA  . ILE B 2 98  ? 127.923 114.508 131.206 1.00 65.72  ? 93  ILE B CA  1 
ATOM 2384 C C   . ILE B 2 98  ? 127.220 113.184 130.935 1.00 65.72  ? 93  ILE B C   1 
ATOM 2385 O O   . ILE B 2 98  ? 125.987 113.155 130.839 1.00 65.72  ? 93  ILE B O   1 
ATOM 2386 C CB  . ILE B 2 98  ? 127.445 115.117 132.530 1.00 65.72  ? 93  ILE B CB  1 
ATOM 2387 C CG1 . ILE B 2 98  ? 128.202 116.408 132.821 1.00 65.72  ? 93  ILE B CG1 1 
ATOM 2388 C CG2 . ILE B 2 98  ? 127.626 114.124 133.656 1.00 65.72  ? 93  ILE B CG2 1 
ATOM 2389 C CD1 . ILE B 2 98  ? 127.622 117.203 133.962 1.00 65.72  ? 93  ILE B CD1 1 
ATOM 2390 N N   . PRO B 2 99  ? 127.944 112.077 130.812 1.00 66.14  ? 94  PRO B N   1 
ATOM 2391 C CA  . PRO B 2 99  ? 127.292 110.773 130.691 1.00 66.14  ? 94  PRO B CA  1 
ATOM 2392 C C   . PRO B 2 99  ? 126.903 110.210 132.048 1.00 66.14  ? 94  PRO B C   1 
ATOM 2393 O O   . PRO B 2 99  ? 127.566 110.431 133.062 1.00 66.14  ? 94  PRO B O   1 
ATOM 2394 C CB  . PRO B 2 99  ? 128.371 109.915 130.022 1.00 66.14  ? 94  PRO B CB  1 
ATOM 2395 C CG  . PRO B 2 99  ? 129.648 110.504 130.496 1.00 66.14  ? 94  PRO B CG  1 
ATOM 2396 C CD  . PRO B 2 99  ? 129.411 111.967 130.775 1.00 66.14  ? 94  PRO B CD  1 
ATOM 2397 N N   . LEU B 2 100 ? 125.801 109.469 132.052 1.00 67.94  ? 95  LEU B N   1 
ATOM 2398 C CA  . LEU B 2 100 ? 125.212 108.950 133.275 1.00 67.94  ? 95  LEU B CA  1 
ATOM 2399 C C   . LEU B 2 100 ? 125.409 107.444 133.371 1.00 67.94  ? 95  LEU B C   1 
ATOM 2400 O O   . LEU B 2 100 ? 125.493 106.738 132.362 1.00 67.94  ? 95  LEU B O   1 
ATOM 2401 C CB  . LEU B 2 100 ? 123.718 109.272 133.340 1.00 67.94  ? 95  LEU B CB  1 
ATOM 2402 C CG  . LEU B 2 100 ? 123.317 110.730 133.517 1.00 67.94  ? 95  LEU B CG  1 
ATOM 2403 C CD1 . LEU B 2 100 ? 121.808 110.844 133.565 1.00 67.94  ? 95  LEU B CD1 1 
ATOM 2404 C CD2 . LEU B 2 100 ? 123.948 111.302 134.763 1.00 67.94  ? 95  LEU B CD2 1 
ATOM 2405 N N   . ARG B 2 101 ? 125.484 106.956 134.609 1.00 67.63  ? 96  ARG B N   1 
ATOM 2406 C CA  . ARG B 2 101 ? 125.569 105.517 134.827 1.00 67.63  ? 96  ARG B CA  1 
ATOM 2407 C C   . ARG B 2 101 ? 124.226 104.836 134.597 1.00 67.63  ? 96  ARG B C   1 
ATOM 2408 O O   . ARG B 2 101 ? 124.167 103.778 133.962 1.00 67.63  ? 96  ARG B O   1 
ATOM 2409 C CB  . ARG B 2 101 ? 126.083 105.228 136.238 1.00 67.63  ? 96  ARG B CB  1 
ATOM 2410 N N   . SER B 2 102 ? 123.143 105.425 135.095 1.00 69.99  ? 97  SER B N   1 
ATOM 2411 C CA  . SER B 2 102 ? 121.801 104.881 134.928 1.00 69.99  ? 97  SER B CA  1 
ATOM 2412 C C   . SER B 2 102 ? 121.060 105.673 133.863 1.00 69.99  ? 97  SER B C   1 
ATOM 2413 O O   . SER B 2 102 ? 121.037 106.908 133.905 1.00 69.99  ? 97  SER B O   1 
ATOM 2414 C CB  . SER B 2 102 ? 121.026 104.916 136.244 1.00 69.99  ? 97  SER B CB  1 
ATOM 2415 O OG  . SER B 2 102 ? 119.751 104.320 136.095 1.00 69.99  ? 97  SER B OG  1 
ATOM 2416 N N   . SER B 2 103 ? 120.454 104.962 132.912 1.00 70.73  ? 98  SER B N   1 
ATOM 2417 C CA  . SER B 2 103 ? 119.853 105.630 131.764 1.00 70.73  ? 98  SER B CA  1 
ATOM 2418 C C   . SER B 2 103 ? 118.599 106.403 132.151 1.00 70.73  ? 98  SER B C   1 
ATOM 2419 O O   . SER B 2 103 ? 118.378 107.518 131.662 1.00 70.73  ? 98  SER B O   1 
ATOM 2420 C CB  . SER B 2 103 ? 119.539 104.610 130.672 1.00 70.73  ? 98  SER B CB  1 
ATOM 2421 O OG  . SER B 2 103 ? 118.490 103.746 131.070 1.00 70.73  ? 98  SER B OG  1 
ATOM 2422 N N   . TRP B 2 104 ? 117.766 105.838 133.019 1.00 69.25  ? 99  TRP B N   1 
ATOM 2423 C CA  . TRP B 2 104 ? 116.462 106.424 133.324 1.00 69.25  ? 99  TRP B CA  1 
ATOM 2424 C C   . TRP B 2 104 ? 116.634 107.493 134.395 1.00 69.25  ? 99  TRP B C   1 
ATOM 2425 O O   . TRP B 2 104 ? 116.943 107.192 135.549 1.00 69.25  ? 99  TRP B O   1 
ATOM 2426 C CB  . TRP B 2 104 ? 115.486 105.344 133.769 1.00 69.25  ? 99  TRP B CB  1 
ATOM 2427 C CG  . TRP B 2 104 ? 115.488 104.142 132.884 1.00 69.25  ? 99  TRP B CG  1 
ATOM 2428 C CD1 . TRP B 2 104 ? 116.262 103.033 133.019 1.00 69.25  ? 99  TRP B CD1 1 
ATOM 2429 C CD2 . TRP B 2 104 ? 114.684 103.928 131.720 1.00 69.25  ? 99  TRP B CD2 1 
ATOM 2430 N NE1 . TRP B 2 104 ? 115.989 102.139 132.017 1.00 69.25  ? 99  TRP B NE1 1 
ATOM 2431 C CE2 . TRP B 2 104 ? 115.022 102.666 131.205 1.00 69.25  ? 99  TRP B CE2 1 
ATOM 2432 C CE3 . TRP B 2 104 ? 113.707 104.681 131.066 1.00 69.25  ? 99  TRP B CE3 1 
ATOM 2433 C CZ2 . TRP B 2 104 ? 114.423 102.142 130.067 1.00 69.25  ? 99  TRP B CZ2 1 
ATOM 2434 C CZ3 . TRP B 2 104 ? 113.115 104.158 129.935 1.00 69.25  ? 99  TRP B CZ3 1 
ATOM 2435 C CH2 . TRP B 2 104 ? 113.476 102.902 129.447 1.00 69.25  ? 99  TRP B CH2 1 
ATOM 2436 N N   . VAL B 2 105 ? 116.432 108.749 134.009 1.00 66.41  ? 100 VAL B N   1 
ATOM 2437 C CA  . VAL B 2 105 ? 116.539 109.892 134.904 1.00 66.41  ? 100 VAL B CA  1 
ATOM 2438 C C   . VAL B 2 105 ? 115.241 110.682 134.829 1.00 66.41  ? 100 VAL B C   1 
ATOM 2439 O O   . VAL B 2 105 ? 114.658 110.829 133.751 1.00 66.41  ? 100 VAL B O   1 
ATOM 2440 C CB  . VAL B 2 105 ? 117.756 110.775 134.549 1.00 66.41  ? 100 VAL B CB  1 
ATOM 2441 C CG1 . VAL B 2 105 ? 117.622 111.353 133.151 1.00 66.41  ? 100 VAL B CG1 1 
ATOM 2442 C CG2 . VAL B 2 105 ? 117.929 111.886 135.567 1.00 66.41  ? 100 VAL B CG2 1 
ATOM 2443 N N   . MET B 2 106 ? 114.767 111.160 135.976 1.00 68.33  ? 101 MET B N   1 
ATOM 2444 C CA  . MET B 2 106 ? 113.513 111.905 136.007 1.00 68.33  ? 101 MET B CA  1 
ATOM 2445 C C   . MET B 2 106 ? 113.590 113.094 136.958 1.00 68.33  ? 101 MET B C   1 
ATOM 2446 O O   . MET B 2 106 ? 112.580 113.497 137.545 1.00 68.33  ? 101 MET B O   1 
ATOM 2447 C CB  . MET B 2 106 ? 112.342 110.992 136.364 1.00 68.33  ? 101 MET B CB  1 
ATOM 2448 C CG  . MET B 2 106 ? 112.584 110.077 137.539 1.00 68.33  ? 101 MET B CG  1 
ATOM 2449 S SD  . MET B 2 106 ? 111.528 108.618 137.470 1.00 68.33  ? 101 MET B SD  1 
ATOM 2450 C CE  . MET B 2 106 ? 109.908 109.354 137.618 1.00 68.33  ? 101 MET B CE  1 
ATOM 2451 N N   . THR B 2 107 ? 114.773 113.689 137.109 1.00 66.58  ? 102 THR B N   1 
ATOM 2452 C CA  . THR B 2 107 ? 114.920 114.917 137.886 1.00 66.58  ? 102 THR B CA  1 
ATOM 2453 C C   . THR B 2 107 ? 116.306 115.504 137.657 1.00 66.58  ? 102 THR B C   1 
ATOM 2454 O O   . THR B 2 107 ? 117.248 114.793 137.295 1.00 66.58  ? 102 THR B O   1 
ATOM 2455 C CB  . THR B 2 107 ? 114.698 114.679 139.383 1.00 66.58  ? 102 THR B CB  1 
ATOM 2456 O OG1 . THR B 2 107 ? 114.637 115.940 140.060 1.00 66.58  ? 102 THR B OG1 1 
ATOM 2457 C CG2 . THR B 2 107 ? 115.829 113.850 139.969 1.00 66.58  ? 102 THR B CG2 1 
ATOM 2458 N N   . CYS B 2 108 ? 116.413 116.814 137.881 1.00 64.29  ? 103 CYS B N   1 
ATOM 2459 C CA  . CYS B 2 108 ? 117.682 117.530 137.839 1.00 64.29  ? 103 CYS B CA  1 
ATOM 2460 C C   . CYS B 2 108 ? 117.606 118.742 138.752 1.00 64.29  ? 103 CYS B C   1 
ATOM 2461 O O   . CYS B 2 108 ? 116.521 119.199 139.121 1.00 64.29  ? 103 CYS B O   1 
ATOM 2462 C CB  . CYS B 2 108 ? 118.058 117.971 136.425 1.00 64.29  ? 103 CYS B CB  1 
ATOM 2463 S SG  . CYS B 2 108 ? 118.621 116.662 135.342 1.00 64.29  ? 103 CYS B SG  1 
ATOM 2464 N N   . ALA B 2 109 ? 118.779 119.257 139.111 1.00 62.09  ? 104 ALA B N   1 
ATOM 2465 C CA  . ALA B 2 109 ? 118.880 120.442 139.949 1.00 62.09  ? 104 ALA B CA  1 
ATOM 2466 C C   . ALA B 2 109 ? 120.171 121.172 139.616 1.00 62.09  ? 104 ALA B C   1 
ATOM 2467 O O   . ALA B 2 109 ? 121.110 120.583 139.078 1.00 62.09  ? 104 ALA B O   1 
ATOM 2468 C CB  . ALA B 2 109 ? 118.838 120.087 141.438 1.00 62.09  ? 104 ALA B CB  1 
ATOM 2469 N N   . TYR B 2 110 ? 120.207 122.464 139.936 1.00 61.13  ? 105 TYR B N   1 
ATOM 2470 C CA  . TYR B 2 110 ? 121.376 123.300 139.688 1.00 61.13  ? 105 TYR B CA  1 
ATOM 2471 C C   . TYR B 2 110 ? 121.703 124.038 140.976 1.00 61.13  ? 105 TYR B C   1 
ATOM 2472 O O   . TYR B 2 110 ? 120.854 124.759 141.508 1.00 61.13  ? 105 TYR B O   1 
ATOM 2473 C CB  . TYR B 2 110 ? 121.114 124.290 138.550 1.00 61.13  ? 105 TYR B CB  1 
ATOM 2474 C CG  . TYR B 2 110 ? 122.361 124.804 137.864 1.00 61.13  ? 105 TYR B CG  1 
ATOM 2475 C CD1 . TYR B 2 110 ? 122.970 124.069 136.863 1.00 61.13  ? 105 TYR B CD1 1 
ATOM 2476 C CD2 . TYR B 2 110 ? 122.925 126.015 138.215 1.00 61.13  ? 105 TYR B CD2 1 
ATOM 2477 C CE1 . TYR B 2 110 ? 124.095 124.524 136.231 1.00 61.13  ? 105 TYR B CE1 1 
ATOM 2478 C CE2 . TYR B 2 110 ? 124.058 126.476 137.587 1.00 61.13  ? 105 TYR B CE2 1 
ATOM 2479 C CZ  . TYR B 2 110 ? 124.638 125.723 136.595 1.00 61.13  ? 105 TYR B CZ  1 
ATOM 2480 O OH  . TYR B 2 110 ? 125.769 126.172 135.960 1.00 61.13  ? 105 TYR B OH  1 
ATOM 2481 N N   . ALA B 2 111 ? 122.920 123.856 141.475 1.00 61.97  ? 106 ALA B N   1 
ATOM 2482 C CA  . ALA B 2 111 ? 123.292 124.440 142.752 1.00 61.97  ? 106 ALA B CA  1 
ATOM 2483 C C   . ALA B 2 111 ? 123.273 125.964 142.669 1.00 61.97  ? 106 ALA B C   1 
ATOM 2484 O O   . ALA B 2 111 ? 123.623 126.542 141.637 1.00 61.97  ? 106 ALA B O   1 
ATOM 2485 C CB  . ALA B 2 111 ? 124.675 123.961 143.175 1.00 61.97  ? 106 ALA B CB  1 
ATOM 2486 N N   . PRO B 2 112 ? 122.852 126.637 143.742 1.00 63.67  ? 107 PRO B N   1 
ATOM 2487 C CA  . PRO B 2 112 ? 122.790 128.107 143.699 1.00 63.67  ? 107 PRO B CA  1 
ATOM 2488 C C   . PRO B 2 112 ? 124.129 128.769 143.434 1.00 63.67  ? 107 PRO B C   1 
ATOM 2489 O O   . PRO B 2 112 ? 124.180 129.798 142.749 1.00 63.67  ? 107 PRO B O   1 
ATOM 2490 C CB  . PRO B 2 112 ? 122.246 128.461 145.086 1.00 63.67  ? 107 PRO B CB  1 
ATOM 2491 C CG  . PRO B 2 112 ? 121.424 127.291 145.454 1.00 63.67  ? 107 PRO B CG  1 
ATOM 2492 C CD  . PRO B 2 112 ? 122.187 126.101 144.938 1.00 63.67  ? 107 PRO B CD  1 
ATOM 2493 N N   . SER B 2 113 ? 125.218 128.209 143.958 1.00 65.61  ? 108 SER B N   1 
ATOM 2494 C CA  . SER B 2 113 ? 126.529 128.811 143.749 1.00 65.61  ? 108 SER B CA  1 
ATOM 2495 C C   . SER B 2 113 ? 126.950 128.755 142.289 1.00 65.61  ? 108 SER B C   1 
ATOM 2496 O O   . SER B 2 113 ? 127.545 129.711 141.779 1.00 65.61  ? 108 SER B O   1 
ATOM 2497 C CB  . SER B 2 113 ? 127.574 128.114 144.616 1.00 65.61  ? 108 SER B CB  1 
ATOM 2498 O OG  . SER B 2 113 ? 128.130 127.002 143.937 1.00 65.61  ? 108 SER B OG  1 
ATOM 2499 N N   . GLY B 2 114 ? 126.654 127.659 141.605 1.00 65.29  ? 109 GLY B N   1 
ATOM 2500 C CA  . GLY B 2 114 ? 127.146 127.436 140.268 1.00 65.29  ? 109 GLY B CA  1 
ATOM 2501 C C   . GLY B 2 114 ? 128.264 126.427 140.165 1.00 65.29  ? 109 GLY B C   1 
ATOM 2502 O O   . GLY B 2 114 ? 129.093 126.543 139.255 1.00 65.29  ? 109 GLY B O   1 
ATOM 2503 N N   . ASN B 2 115 ? 128.317 125.447 141.063 1.00 67.25  ? 110 ASN B N   1 
ATOM 2504 C CA  . ASN B 2 115 ? 129.384 124.459 141.077 1.00 67.25  ? 110 ASN B CA  1 
ATOM 2505 C C   . ASN B 2 115 ? 128.903 123.036 140.848 1.00 67.25  ? 110 ASN B C   1 
ATOM 2506 O O   . ASN B 2 115 ? 129.673 122.211 140.350 1.00 67.25  ? 110 ASN B O   1 
ATOM 2507 C CB  . ASN B 2 115 ? 130.127 124.510 142.414 1.00 67.25  ? 110 ASN B CB  1 
ATOM 2508 C CG  . ASN B 2 115 ? 130.845 125.817 142.631 1.00 67.25  ? 110 ASN B CG  1 
ATOM 2509 O OD1 . ASN B 2 115 ? 130.245 126.887 142.536 1.00 67.25  ? 110 ASN B OD1 1 
ATOM 2510 N ND2 . ASN B 2 115 ? 132.135 125.744 142.934 1.00 67.25  ? 110 ASN B ND2 1 
ATOM 2511 N N   . TYR B 2 116 ? 127.659 122.720 141.200 1.00 64.43  ? 111 TYR B N   1 
ATOM 2512 C CA  . TYR B 2 116 ? 127.197 121.342 141.264 1.00 64.43  ? 111 TYR B CA  1 
ATOM 2513 C C   . TYR B 2 116 ? 125.939 121.150 140.432 1.00 64.43  ? 111 TYR B C   1 
ATOM 2514 O O   . TYR B 2 116 ? 125.160 122.084 140.225 1.00 64.43  ? 111 TYR B O   1 
ATOM 2515 C CB  . TYR B 2 116 ? 126.908 120.931 142.707 1.00 64.43  ? 111 TYR B CB  1 
ATOM 2516 C CG  . TYR B 2 116 ? 128.121 120.895 143.603 1.00 64.43  ? 111 TYR B CG  1 
ATOM 2517 C CD1 . TYR B 2 116 ? 129.376 120.636 143.091 1.00 64.43  ? 111 TYR B CD1 1 
ATOM 2518 C CD2 . TYR B 2 116 ? 128.004 121.117 144.964 1.00 64.43  ? 111 TYR B CD2 1 
ATOM 2519 C CE1 . TYR B 2 116 ? 130.481 120.600 143.906 1.00 64.43  ? 111 TYR B CE1 1 
ATOM 2520 C CE2 . TYR B 2 116 ? 129.107 121.082 145.786 1.00 64.43  ? 111 TYR B CE2 1 
ATOM 2521 C CZ  . TYR B 2 116 ? 130.341 120.823 145.251 1.00 64.43  ? 111 TYR B CZ  1 
ATOM 2522 O OH  . TYR B 2 116 ? 131.446 120.786 146.063 1.00 64.43  ? 111 TYR B OH  1 
ATOM 2523 N N   . VAL B 2 117 ? 125.748 119.921 139.959 1.00 61.84  ? 112 VAL B N   1 
ATOM 2524 C CA  . VAL B 2 117 ? 124.515 119.498 139.304 1.00 61.84  ? 112 VAL B CA  1 
ATOM 2525 C C   . VAL B 2 117 ? 124.142 118.125 139.840 1.00 61.84  ? 112 VAL B C   1 
ATOM 2526 O O   . VAL B 2 117 ? 125.009 117.266 140.029 1.00 61.84  ? 112 VAL B O   1 
ATOM 2527 C CB  . VAL B 2 117 ? 124.649 119.469 137.769 1.00 61.84  ? 112 VAL B CB  1 
ATOM 2528 C CG1 . VAL B 2 117 ? 124.672 120.876 137.215 1.00 61.84  ? 112 VAL B CG1 1 
ATOM 2529 C CG2 . VAL B 2 117 ? 125.900 118.720 137.358 1.00 61.84  ? 112 VAL B CG2 1 
ATOM 2530 N N   . ALA B 2 118 ? 122.852 117.918 140.091 1.00 61.51  ? 113 ALA B N   1 
ATOM 2531 C CA  . ALA B 2 118 ? 122.357 116.692 140.695 1.00 61.51  ? 113 ALA B CA  1 
ATOM 2532 C C   . ALA B 2 118 ? 121.330 116.030 139.788 1.00 61.51  ? 113 ALA B C   1 
ATOM 2533 O O   . ALA B 2 118 ? 120.547 116.704 139.114 1.00 61.51  ? 113 ALA B O   1 
ATOM 2534 C CB  . ALA B 2 118 ? 121.736 116.966 142.066 1.00 61.51  ? 113 ALA B CB  1 
ATOM 2535 N N   . CYS B 2 119 ? 121.340 114.700 139.777 1.00 64.64  ? 114 CYS B N   1 
ATOM 2536 C CA  . CYS B 2 119 ? 120.427 113.926 138.948 1.00 64.64  ? 114 CYS B CA  1 
ATOM 2537 C C   . CYS B 2 119 ? 120.076 112.632 139.664 1.00 64.64  ? 114 CYS B C   1 
ATOM 2538 O O   . CYS B 2 119 ? 120.825 112.147 140.515 1.00 64.64  ? 114 CYS B O   1 
ATOM 2539 C CB  . CYS B 2 119 ? 121.033 113.621 137.579 1.00 64.64  ? 114 CYS B CB  1 
ATOM 2540 S SG  . CYS B 2 119 ? 122.089 112.164 137.572 1.00 64.64  ? 114 CYS B SG  1 
ATOM 2541 N N   . GLY B 2 120 ? 118.927 112.074 139.307 1.00 66.14  ? 115 GLY B N   1 
ATOM 2542 C CA  . GLY B 2 120 ? 118.463 110.844 139.923 1.00 66.14  ? 115 GLY B CA  1 
ATOM 2543 C C   . GLY B 2 120 ? 117.232 110.339 139.206 1.00 66.14  ? 115 GLY B C   1 
ATOM 2544 O O   . GLY B 2 120 ? 116.604 111.055 138.419 1.00 66.14  ? 115 GLY B O   1 
ATOM 2545 N N   . GLY B 2 121 ? 116.890 109.085 139.491 1.00 69.19  ? 116 GLY B N   1 
ATOM 2546 C CA  . GLY B 2 121 ? 115.760 108.464 138.829 1.00 69.19  ? 116 GLY B CA  1 
ATOM 2547 C C   . GLY B 2 121 ? 115.354 107.116 139.385 1.00 69.19  ? 116 GLY B C   1 
ATOM 2548 O O   . GLY B 2 121 ? 115.289 106.932 140.603 1.00 69.19  ? 116 GLY B O   1 
ATOM 2549 N N   . LEU B 2 122 ? 115.074 106.163 138.497 1.00 69.77  ? 117 LEU B N   1 
ATOM 2550 C CA  . LEU B 2 122 ? 114.650 104.830 138.906 1.00 69.77  ? 117 LEU B CA  1 
ATOM 2551 C C   . LEU B 2 122 ? 115.765 104.032 139.566 1.00 69.77  ? 117 LEU B C   1 
ATOM 2552 O O   . LEU B 2 122 ? 115.501 102.937 140.070 1.00 69.77  ? 117 LEU B O   1 
ATOM 2553 C CB  . LEU B 2 122 ? 114.119 104.053 137.702 1.00 69.77  ? 117 LEU B CB  1 
ATOM 2554 C CG  . LEU B 2 122 ? 112.660 104.263 137.308 1.00 69.77  ? 117 LEU B CG  1 
ATOM 2555 C CD1 . LEU B 2 122 ? 112.267 103.284 136.223 1.00 69.77  ? 117 LEU B CD1 1 
ATOM 2556 C CD2 . LEU B 2 122 ? 111.759 104.105 138.511 1.00 69.77  ? 117 LEU B CD2 1 
ATOM 2557 N N   . ASP B 2 123 ? 116.992 104.542 139.574 1.00 71.75  ? 118 ASP B N   1 
ATOM 2558 C CA  . ASP B 2 123 ? 118.118 103.822 140.149 1.00 71.75  ? 118 ASP B CA  1 
ATOM 2559 C C   . ASP B 2 123 ? 118.241 104.008 141.654 1.00 71.75  ? 118 ASP B C   1 
ATOM 2560 O O   . ASP B 2 123 ? 119.180 103.466 142.247 1.00 71.75  ? 118 ASP B O   1 
ATOM 2561 C CB  . ASP B 2 123 ? 119.419 104.254 139.469 1.00 71.75  ? 118 ASP B CB  1 
ATOM 2562 C CG  . ASP B 2 123 ? 119.681 105.742 139.601 1.00 71.75  ? 118 ASP B CG  1 
ATOM 2563 O OD1 . ASP B 2 123 ? 118.754 106.482 139.993 1.00 71.75  ? 118 ASP B OD1 1 
ATOM 2564 O OD2 . ASP B 2 123 ? 120.817 106.173 139.313 1.00 71.75  ? 118 ASP B OD2 1 
ATOM 2565 N N   . ASN B 2 124 ? 117.325 104.752 142.270 1.00 70.29  ? 119 ASN B N   1 
ATOM 2566 C CA  . ASN B 2 124 ? 117.323 104.918 143.732 1.00 70.29  ? 119 ASN B CA  1 
ATOM 2567 C C   . ASN B 2 124 ? 118.560 105.629 144.278 1.00 70.29  ? 119 ASN B C   1 
ATOM 2568 O O   . ASN B 2 124 ? 118.886 105.480 145.455 1.00 70.29  ? 119 ASN B O   1 
ATOM 2569 C CB  . ASN B 2 124 ? 117.174 103.555 144.422 1.00 70.29  ? 119 ASN B CB  1 
ATOM 2570 C CG  . ASN B 2 124 ? 116.028 102.736 143.858 1.00 70.29  ? 119 ASN B CG  1 
ATOM 2571 O OD1 . ASN B 2 124 ? 115.334 103.165 142.937 1.00 70.29  ? 119 ASN B OD1 1 
ATOM 2572 N ND2 . ASN B 2 124 ? 115.827 101.545 144.411 1.00 70.29  ? 119 ASN B ND2 1 
ATOM 2573 N N   . ILE B 2 125 ? 119.238 106.408 143.444 1.00 68.69  ? 120 ILE B N   1 
ATOM 2574 C CA  . ILE B 2 125 ? 120.448 107.103 143.862 1.00 68.69  ? 120 ILE B CA  1 
ATOM 2575 C C   . ILE B 2 125 ? 120.347 108.562 143.445 1.00 68.69  ? 120 ILE B C   1 
ATOM 2576 O O   . ILE B 2 125 ? 119.888 108.871 142.339 1.00 68.69  ? 120 ILE B O   1 
ATOM 2577 C CB  . ILE B 2 125 ? 121.711 106.457 143.254 1.00 68.69  ? 120 ILE B CB  1 
ATOM 2578 C CG1 . ILE B 2 125 ? 121.752 104.963 143.561 1.00 68.69  ? 120 ILE B CG1 1 
ATOM 2579 C CG2 . ILE B 2 125 ? 122.966 107.135 143.775 1.00 68.69  ? 120 ILE B CG2 1 
ATOM 2580 C CD1 . ILE B 2 125 ? 121.785 104.650 145.030 1.00 68.69  ? 120 ILE B CD1 1 
ATOM 2581 N N   . CYS B 2 126 ? 120.778 109.461 144.327 1.00 68.25  ? 121 CYS B N   1 
ATOM 2582 C CA  . CYS B 2 126 ? 120.851 110.891 144.039 1.00 68.25  ? 121 CYS B CA  1 
ATOM 2583 C C   . CYS B 2 126 ? 122.321 111.253 143.854 1.00 68.25  ? 121 CYS B C   1 
ATOM 2584 O O   . CYS B 2 126 ? 123.056 111.418 144.832 1.00 68.25  ? 121 CYS B O   1 
ATOM 2585 C CB  . CYS B 2 126 ? 120.212 111.706 145.156 1.00 68.25  ? 121 CYS B CB  1 
ATOM 2586 S SG  . CYS B 2 126 ? 119.699 113.361 144.671 1.00 68.25  ? 121 CYS B SG  1 
ATOM 2587 N N   . SER B 2 127 ? 122.748 111.374 142.603 1.00 64.64  ? 122 SER B N   1 
ATOM 2588 C CA  . SER B 2 127 ? 124.138 111.660 142.286 1.00 64.64  ? 122 SER B CA  1 
ATOM 2589 C C   . SER B 2 127 ? 124.410 113.158 142.337 1.00 64.64  ? 122 SER B C   1 
ATOM 2590 O O   . SER B 2 127 ? 123.538 113.977 142.040 1.00 64.64  ? 122 SER B O   1 
ATOM 2591 C CB  . SER B 2 127 ? 124.495 111.117 140.904 1.00 64.64  ? 122 SER B CB  1 
ATOM 2592 O OG  . SER B 2 127 ? 124.397 109.707 140.868 1.00 64.64  ? 122 SER B OG  1 
ATOM 2593 N N   . ILE B 2 128 ? 125.634 113.509 142.721 1.00 62.39  ? 123 ILE B N   1 
ATOM 2594 C CA  . ILE B 2 128 ? 126.087 114.895 142.769 1.00 62.39  ? 123 ILE B CA  1 
ATOM 2595 C C   . ILE B 2 128 ? 127.368 115.007 141.954 1.00 62.39  ? 123 ILE B C   1 
ATOM 2596 O O   . ILE B 2 128 ? 128.264 114.168 142.086 1.00 62.39  ? 123 ILE B O   1 
ATOM 2597 C CB  . ILE B 2 128 ? 126.313 115.372 144.214 1.00 62.39  ? 123 ILE B CB  1 
ATOM 2598 C CG1 . ILE B 2 128 ? 124.984 115.466 144.953 1.00 62.39  ? 123 ILE B CG1 1 
ATOM 2599 C CG2 . ILE B 2 128 ? 127.016 116.713 144.237 1.00 62.39  ? 123 ILE B CG2 1 
ATOM 2600 C CD1 . ILE B 2 128 ? 125.130 115.691 146.436 1.00 62.39  ? 123 ILE B CD1 1 
ATOM 2601 N N   . TYR B 2 129 ? 127.453 116.037 141.113 1.00 62.44  ? 124 TYR B N   1 
ATOM 2602 C CA  . TYR B 2 129 ? 128.567 116.211 140.193 1.00 62.44  ? 124 TYR B CA  1 
ATOM 2603 C C   . TYR B 2 129 ? 129.306 117.506 140.500 1.00 62.44  ? 124 TYR B C   1 
ATOM 2604 O O   . TYR B 2 129 ? 128.722 118.463 141.014 1.00 62.44  ? 124 TYR B O   1 
ATOM 2605 C CB  . TYR B 2 129 ? 128.084 116.217 138.744 1.00 62.44  ? 124 TYR B CB  1 
ATOM 2606 C CG  . TYR B 2 129 ? 127.621 114.871 138.247 1.00 62.44  ? 124 TYR B CG  1 
ATOM 2607 C CD1 . TYR B 2 129 ? 126.434 114.320 138.689 1.00 62.44  ? 124 TYR B CD1 1 
ATOM 2608 C CD2 . TYR B 2 129 ? 128.372 114.152 137.337 1.00 62.44  ? 124 TYR B CD2 1 
ATOM 2609 C CE1 . TYR B 2 129 ? 126.010 113.091 138.238 1.00 62.44  ? 124 TYR B CE1 1 
ATOM 2610 C CE2 . TYR B 2 129 ? 127.955 112.925 136.883 1.00 62.44  ? 124 TYR B CE2 1 
ATOM 2611 C CZ  . TYR B 2 129 ? 126.776 112.400 137.337 1.00 62.44  ? 124 TYR B CZ  1 
ATOM 2612 O OH  . TYR B 2 129 ? 126.357 111.174 136.885 1.00 62.44  ? 124 TYR B OH  1 
ATOM 2613 N N   . ASN B 2 130 ? 130.602 117.531 140.180 1.00 66.82  ? 125 ASN B N   1 
ATOM 2614 C CA  . ASN B 2 130 ? 131.481 118.660 140.476 1.00 66.82  ? 125 ASN B CA  1 
ATOM 2615 C C   . ASN B 2 130 ? 131.932 119.294 139.167 1.00 66.82  ? 125 ASN B C   1 
ATOM 2616 O O   . ASN B 2 130 ? 132.744 118.713 138.440 1.00 66.82  ? 125 ASN B O   1 
ATOM 2617 C CB  . ASN B 2 130 ? 132.683 118.209 141.302 1.00 66.82  ? 125 ASN B CB  1 
ATOM 2618 C CG  . ASN B 2 130 ? 133.441 119.366 141.907 1.00 66.82  ? 125 ASN B CG  1 
ATOM 2619 O OD1 . ASN B 2 130 ? 133.104 120.528 141.688 1.00 66.82  ? 125 ASN B OD1 1 
ATOM 2620 N ND2 . ASN B 2 130 ? 134.475 119.055 142.676 1.00 66.82  ? 125 ASN B ND2 1 
ATOM 2621 N N   . LEU B 2 131 ? 131.424 120.494 138.879 1.00 67.28  ? 126 LEU B N   1 
ATOM 2622 C CA  . LEU B 2 131 ? 131.693 121.136 137.597 1.00 67.28  ? 126 LEU B CA  1 
ATOM 2623 C C   . LEU B 2 131 ? 133.083 121.757 137.534 1.00 67.28  ? 126 LEU B C   1 
ATOM 2624 O O   . LEU B 2 131 ? 133.727 121.731 136.480 1.00 67.28  ? 126 LEU B O   1 
ATOM 2625 C CB  . LEU B 2 131 ? 130.634 122.200 137.313 1.00 67.28  ? 126 LEU B CB  1 
ATOM 2626 C CG  . LEU B 2 131 ? 129.230 121.698 136.990 1.00 67.28  ? 126 LEU B CG  1 
ATOM 2627 C CD1 . LEU B 2 131 ? 128.358 122.837 136.510 1.00 67.28  ? 126 LEU B CD1 1 
ATOM 2628 C CD2 . LEU B 2 131 ? 129.289 120.598 135.947 1.00 67.28  ? 126 LEU B CD2 1 
ATOM 2629 N N   . LYS B 2 132 ? 133.563 122.317 138.637 1.00 68.81  ? 127 LYS B N   1 
ATOM 2630 C CA  . LYS B 2 132 ? 134.804 123.087 138.658 1.00 68.81  ? 127 LYS B CA  1 
ATOM 2631 C C   . LYS B 2 132 ? 135.876 122.285 139.386 1.00 68.81  ? 127 LYS B C   1 
ATOM 2632 O O   . LYS B 2 132 ? 135.933 122.282 140.618 1.00 68.81  ? 127 LYS B O   1 
ATOM 2633 C CB  . LYS B 2 132 ? 134.583 124.441 139.321 1.00 68.81  ? 127 LYS B CB  1 
ATOM 2634 C CG  . LYS B 2 132 ? 133.753 125.400 138.495 1.00 68.81  ? 127 LYS B CG  1 
ATOM 2635 C CD  . LYS B 2 132 ? 133.279 126.575 139.327 1.00 68.81  ? 127 LYS B CD  1 
ATOM 2636 C CE  . LYS B 2 132 ? 132.637 127.639 138.458 1.00 68.81  ? 127 LYS B CE  1 
ATOM 2637 N NZ  . LYS B 2 132 ? 133.083 129.005 138.836 1.00 68.81  ? 127 LYS B NZ  1 
ATOM 2638 N N   . THR B 2 133 ? 136.730 121.616 138.622 1.00 74.02  ? 128 THR B N   1 
ATOM 2639 C CA  . THR B 2 133 ? 137.850 120.865 139.160 1.00 74.02  ? 128 THR B CA  1 
ATOM 2640 C C   . THR B 2 133 ? 139.156 121.445 138.635 1.00 74.02  ? 128 THR B C   1 
ATOM 2641 O O   . THR B 2 133 ? 139.171 122.307 137.753 1.00 74.02  ? 128 THR B O   1 
ATOM 2642 C CB  . THR B 2 133 ? 137.753 119.381 138.794 1.00 74.02  ? 128 THR B CB  1 
ATOM 2643 O OG1 . THR B 2 133 ? 137.563 119.250 137.380 1.00 74.02  ? 128 THR B OG1 1 
ATOM 2644 C CG2 . THR B 2 133 ? 136.586 118.730 139.520 1.00 74.02  ? 128 THR B CG2 1 
ATOM 2645 N N   . ARG B 2 134 ? 140.265 120.962 139.197 1.00 76.64  ? 129 ARG B N   1 
ATOM 2646 C CA  . ARG B 2 134 ? 141.575 121.374 138.704 1.00 76.64  ? 129 ARG B CA  1 
ATOM 2647 C C   . ARG B 2 134 ? 141.781 120.922 137.266 1.00 76.64  ? 129 ARG B C   1 
ATOM 2648 O O   . ARG B 2 134 ? 142.312 121.674 136.440 1.00 76.64  ? 129 ARG B O   1 
ATOM 2649 C CB  . ARG B 2 134 ? 142.674 120.822 139.608 1.00 76.64  ? 129 ARG B CB  1 
ATOM 2650 N N   . GLU B 2 135 ? 141.367 119.702 136.946 1.00 79.68  ? 130 GLU B N   1 
ATOM 2651 C CA  . GLU B 2 135 ? 141.381 119.224 135.575 1.00 79.68  ? 130 GLU B CA  1 
ATOM 2652 C C   . GLU B 2 135 ? 140.089 119.631 134.872 1.00 79.68  ? 130 GLU B C   1 
ATOM 2653 O O   . GLU B 2 135 ? 139.107 120.031 135.499 1.00 79.68  ? 130 GLU B O   1 
ATOM 2654 C CB  . GLU B 2 135 ? 141.564 117.709 135.535 1.00 79.68  ? 130 GLU B CB  1 
ATOM 2655 C CG  . GLU B 2 135 ? 142.813 117.214 136.238 1.00 79.68  ? 130 GLU B CG  1 
ATOM 2656 C CD  . GLU B 2 135 ? 142.603 116.989 137.722 1.00 79.68  ? 130 GLU B CD  1 
ATOM 2657 O OE1 . GLU B 2 135 ? 141.460 117.158 138.197 1.00 79.68  ? 130 GLU B OE1 1 
ATOM 2658 O OE2 . GLU B 2 135 ? 143.581 116.637 138.414 1.00 79.68  ? 130 GLU B OE2 1 
ATOM 2659 N N   . GLY B 2 136 ? 140.096 119.527 133.544 1.00 78.13  ? 131 GLY B N   1 
ATOM 2660 C CA  . GLY B 2 136 ? 138.976 120.024 132.768 1.00 78.13  ? 131 GLY B CA  1 
ATOM 2661 C C   . GLY B 2 136 ? 137.735 119.162 132.833 1.00 78.13  ? 131 GLY B C   1 
ATOM 2662 O O   . GLY B 2 136 ? 136.635 119.662 132.579 1.00 78.13  ? 131 GLY B O   1 
ATOM 2663 N N   . ASN B 2 137 ? 137.882 117.885 133.165 1.00 77.42  ? 132 ASN B N   1 
ATOM 2664 C CA  . ASN B 2 137 ? 136.752 116.974 133.150 1.00 77.42  ? 132 ASN B CA  1 
ATOM 2665 C C   . ASN B 2 137 ? 135.844 117.193 134.360 1.00 77.42  ? 132 ASN B C   1 
ATOM 2666 O O   . ASN B 2 137 ? 136.199 117.860 135.333 1.00 77.42  ? 132 ASN B O   1 
ATOM 2667 C CB  . ASN B 2 137 ? 137.247 115.524 133.029 1.00 77.42  ? 132 ASN B CB  1 
ATOM 2668 C CG  . ASN B 2 137 ? 137.736 114.916 134.352 1.00 77.42  ? 132 ASN B CG  1 
ATOM 2669 O OD1 . ASN B 2 137 ? 137.585 115.478 135.436 1.00 77.42  ? 132 ASN B OD1 1 
ATOM 2670 N ND2 . ASN B 2 137 ? 138.333 113.733 134.248 1.00 77.42  ? 132 ASN B ND2 1 
ATOM 2671 N N   . VAL B 2 138 ? 134.647 116.620 134.276 1.00 70.97  ? 133 VAL B N   1 
ATOM 2672 C CA  . VAL B 2 138 ? 133.658 116.658 135.346 1.00 70.97  ? 133 VAL B CA  1 
ATOM 2673 C C   . VAL B 2 138 ? 133.479 115.241 135.875 1.00 70.97  ? 133 VAL B C   1 
ATOM 2674 O O   . VAL B 2 138 ? 133.334 114.292 135.095 1.00 70.97  ? 133 VAL B O   1 
ATOM 2675 C CB  . VAL B 2 138 ? 132.329 117.260 134.856 1.00 70.97  ? 133 VAL B CB  1 
ATOM 2676 C CG1 . VAL B 2 138 ? 131.777 116.474 133.682 1.00 70.97  ? 133 VAL B CG1 1 
ATOM 2677 C CG2 . VAL B 2 138 ? 131.318 117.306 135.984 1.00 70.97  ? 133 VAL B CG2 1 
ATOM 2678 N N   . ARG B 2 139 ? 133.515 115.092 137.197 1.00 70.20  ? 134 ARG B N   1 
ATOM 2679 C CA  . ARG B 2 139 ? 133.515 113.783 137.827 1.00 70.20  ? 134 ARG B CA  1 
ATOM 2680 C C   . ARG B 2 139 ? 132.495 113.737 138.956 1.00 70.20  ? 134 ARG B C   1 
ATOM 2681 O O   . ARG B 2 139 ? 132.027 114.768 139.446 1.00 70.20  ? 134 ARG B O   1 
ATOM 2682 C CB  . ARG B 2 139 ? 134.904 113.425 138.361 1.00 70.20  ? 134 ARG B CB  1 
ATOM 2683 C CG  . ARG B 2 139 ? 135.361 114.280 139.524 1.00 70.20  ? 134 ARG B CG  1 
ATOM 2684 C CD  . ARG B 2 139 ? 136.813 114.005 139.863 1.00 70.20  ? 134 ARG B CD  1 
ATOM 2685 N NE  . ARG B 2 139 ? 137.036 112.605 140.207 1.00 70.20  ? 134 ARG B NE  1 
ATOM 2686 C CZ  . ARG B 2 139 ? 136.874 112.100 141.425 1.00 70.20  ? 134 ARG B CZ  1 
ATOM 2687 N NH1 . ARG B 2 139 ? 136.485 112.880 142.423 1.00 70.20  ? 134 ARG B NH1 1 
ATOM 2688 N NH2 . ARG B 2 139 ? 137.101 110.811 141.645 1.00 70.20  ? 134 ARG B NH2 1 
ATOM 2689 N N   . VAL B 2 140 ? 132.160 112.516 139.361 1.00 64.57  ? 135 VAL B N   1 
ATOM 2690 C CA  . VAL B 2 140 ? 131.143 112.282 140.381 1.00 64.57  ? 135 VAL B CA  1 
ATOM 2691 C C   . VAL B 2 140 ? 131.748 112.509 141.757 1.00 64.57  ? 135 VAL B C   1 
ATOM 2692 O O   . VAL B 2 140 ? 132.802 111.952 142.084 1.00 64.57  ? 135 VAL B O   1 
ATOM 2693 C CB  . VAL B 2 140 ? 130.575 110.861 140.259 1.00 64.57  ? 135 VAL B CB  1 
ATOM 2694 C CG1 . VAL B 2 140 ? 129.652 110.558 141.424 1.00 64.57  ? 135 VAL B CG1 1 
ATOM 2695 C CG2 . VAL B 2 140 ? 129.851 110.691 138.941 1.00 64.57  ? 135 VAL B CG2 1 
ATOM 2696 N N   . SER B 2 141 ? 131.080 113.323 142.574 1.00 66.12  ? 136 SER B N   1 
ATOM 2697 C CA  . SER B 2 141 ? 131.601 113.631 143.900 1.00 66.12  ? 136 SER B CA  1 
ATOM 2698 C C   . SER B 2 141 ? 131.179 112.579 144.918 1.00 66.12  ? 136 SER B C   1 
ATOM 2699 O O   . SER B 2 141 ? 132.025 111.926 145.537 1.00 66.12  ? 136 SER B O   1 
ATOM 2700 C CB  . SER B 2 141 ? 131.137 115.020 144.339 1.00 66.12  ? 136 SER B CB  1 
ATOM 2701 O OG  . SER B 2 141 ? 131.752 115.399 145.557 1.00 66.12  ? 136 SER B OG  1 
ATOM 2702 N N   . ARG B 2 142 ? 129.873 112.400 145.107 1.00 69.77  ? 137 ARG B N   1 
ATOM 2703 C CA  . ARG B 2 142 ? 129.386 111.417 146.065 1.00 69.77  ? 137 ARG B CA  1 
ATOM 2704 C C   . ARG B 2 142 ? 128.003 110.944 145.649 1.00 69.77  ? 137 ARG B C   1 
ATOM 2705 O O   . ARG B 2 142 ? 127.179 111.750 145.207 1.00 69.77  ? 137 ARG B O   1 
ATOM 2706 C CB  . ARG B 2 142 ? 129.349 112.002 147.476 1.00 69.77  ? 137 ARG B CB  1 
ATOM 2707 C CG  . ARG B 2 142 ? 128.827 111.038 148.516 1.00 69.77  ? 137 ARG B CG  1 
ATOM 2708 C CD  . ARG B 2 142 ? 128.983 111.611 149.905 1.00 69.77  ? 137 ARG B CD  1 
ATOM 2709 N NE  . ARG B 2 142 ? 130.378 111.906 150.219 1.00 69.77  ? 137 ARG B NE  1 
ATOM 2710 C CZ  . ARG B 2 142 ? 131.296 110.987 150.490 1.00 69.77  ? 137 ARG B CZ  1 
ATOM 2711 N NH1 . ARG B 2 142 ? 130.973 109.701 150.502 1.00 69.77  ? 137 ARG B NH1 1 
ATOM 2712 N NH2 . ARG B 2 142 ? 132.540 111.354 150.763 1.00 69.77  ? 137 ARG B NH2 1 
ATOM 2713 N N   . GLU B 2 143 ? 127.756 109.644 145.793 1.00 70.57  ? 138 GLU B N   1 
ATOM 2714 C CA  . GLU B 2 143 ? 126.468 109.038 145.476 1.00 70.57  ? 138 GLU B CA  1 
ATOM 2715 C C   . GLU B 2 143 ? 125.723 108.765 146.777 1.00 70.57  ? 138 GLU B C   1 
ATOM 2716 O O   . GLU B 2 143 ? 126.246 108.090 147.669 1.00 70.57  ? 138 GLU B O   1 
ATOM 2717 C CB  . GLU B 2 143 ? 126.650 107.751 144.676 1.00 70.57  ? 138 GLU B CB  1 
ATOM 2718 C CG  . GLU B 2 143 ? 127.672 107.853 143.568 1.00 70.57  ? 138 GLU B CG  1 
ATOM 2719 C CD  . GLU B 2 143 ? 127.607 106.679 142.615 1.00 70.57  ? 138 GLU B CD  1 
ATOM 2720 O OE1 . GLU B 2 143 ? 128.532 106.530 141.788 1.00 70.57  ? 138 GLU B OE1 1 
ATOM 2721 O OE2 . GLU B 2 143 ? 126.630 105.906 142.691 1.00 70.57  ? 138 GLU B OE2 1 
ATOM 2722 N N   . LEU B 2 144 ? 124.506 109.286 146.881 1.00 69.08  ? 139 LEU B N   1 
ATOM 2723 C CA  . LEU B 2 144 ? 123.714 109.129 148.089 1.00 69.08  ? 139 LEU B CA  1 
ATOM 2724 C C   . LEU B 2 144 ? 122.722 107.985 147.920 1.00 69.08  ? 139 LEU B C   1 
ATOM 2725 O O   . LEU B 2 144 ? 122.005 107.917 146.916 1.00 69.08  ? 139 LEU B O   1 
ATOM 2726 C CB  . LEU B 2 144 ? 122.981 110.427 148.411 1.00 69.08  ? 139 LEU B CB  1 
ATOM 2727 C CG  . LEU B 2 144 ? 123.872 111.657 148.555 1.00 69.08  ? 139 LEU B CG  1 
ATOM 2728 C CD1 . LEU B 2 144 ? 123.041 112.886 148.854 1.00 69.08  ? 139 LEU B CD1 1 
ATOM 2729 C CD2 . LEU B 2 144 ? 124.919 111.436 149.632 1.00 69.08  ? 139 LEU B CD2 1 
ATOM 2730 N N   . ALA B 2 145 ? 122.678 107.092 148.903 1.00 70.69  ? 140 ALA B N   1 
ATOM 2731 C CA  . ALA B 2 145 ? 121.821 105.919 148.870 1.00 70.69  ? 140 ALA B CA  1 
ATOM 2732 C C   . ALA B 2 145 ? 121.099 105.763 150.198 1.00 70.69  ? 140 ALA B C   1 
ATOM 2733 O O   . ALA B 2 145 ? 121.571 106.219 151.242 1.00 70.69  ? 140 ALA B O   1 
ATOM 2734 C CB  . ALA B 2 145 ? 122.623 104.651 148.564 1.00 70.69  ? 140 ALA B CB  1 
ATOM 2735 N N   . GLY B 2 146 ? 119.947 105.099 150.156 1.00 70.30  ? 141 GLY B N   1 
ATOM 2736 C CA  . GLY B 2 146 ? 119.196 104.864 151.372 1.00 70.30  ? 141 GLY B CA  1 
ATOM 2737 C C   . GLY B 2 146 ? 117.687 104.862 151.241 1.00 70.30  ? 141 GLY B C   1 
ATOM 2738 O O   . GLY B 2 146 ? 116.991 104.516 152.199 1.00 70.30  ? 141 GLY B O   1 
ATOM 2739 N N   . HIS B 2 147 ? 117.159 105.241 150.083 1.00 71.06  ? 142 HIS B N   1 
ATOM 2740 C CA  . HIS B 2 147 ? 115.726 105.134 149.862 1.00 71.06  ? 142 HIS B CA  1 
ATOM 2741 C C   . HIS B 2 147 ? 115.341 103.713 149.466 1.00 71.06  ? 142 HIS B C   1 
ATOM 2742 O O   . HIS B 2 147 ? 116.179 102.819 149.343 1.00 71.06  ? 142 HIS B O   1 
ATOM 2743 C CB  . HIS B 2 147 ? 115.251 106.111 148.790 1.00 71.06  ? 142 HIS B CB  1 
ATOM 2744 C CG  . HIS B 2 147 ? 115.111 107.520 149.268 1.00 71.06  ? 142 HIS B CG  1 
ATOM 2745 N ND1 . HIS B 2 147 ? 114.083 107.926 150.088 1.00 71.06  ? 142 HIS B ND1 1 
ATOM 2746 C CD2 . HIS B 2 147 ? 115.843 108.628 149.008 1.00 71.06  ? 142 HIS B CD2 1 
ATOM 2747 C CE1 . HIS B 2 147 ? 114.199 109.217 150.331 1.00 71.06  ? 142 HIS B CE1 1 
ATOM 2748 N NE2 . HIS B 2 147 ? 115.260 109.667 149.688 1.00 71.06  ? 142 HIS B NE2 1 
ATOM 2749 N N   . THR B 2 148 ? 114.041 103.515 149.263 1.00 74.64  ? 143 THR B N   1 
ATOM 2750 C CA  . THR B 2 148 ? 113.481 102.232 148.859 1.00 74.64  ? 143 THR B CA  1 
ATOM 2751 C C   . THR B 2 148 ? 112.800 102.286 147.499 1.00 74.64  ? 143 THR B C   1 
ATOM 2752 O O   . THR B 2 148 ? 112.886 101.325 146.729 1.00 74.64  ? 143 THR B O   1 
ATOM 2753 C CB  . THR B 2 148 ? 112.481 101.743 149.908 1.00 74.64  ? 143 THR B CB  1 
ATOM 2754 O OG1 . THR B 2 148 ? 113.105 101.740 151.197 1.00 74.64  ? 143 THR B OG1 1 
ATOM 2755 C CG2 . THR B 2 148 ? 112.016 100.333 149.586 1.00 74.64  ? 143 THR B CG2 1 
ATOM 2756 N N   . GLY B 2 149 ? 112.141 103.395 147.175 1.00 73.82  ? 144 GLY B N   1 
ATOM 2757 C CA  . GLY B 2 149 ? 111.436 103.518 145.915 1.00 73.82  ? 144 GLY B CA  1 
ATOM 2758 C C   . GLY B 2 149 ? 112.188 104.316 144.870 1.00 73.82  ? 144 GLY B C   1 
ATOM 2759 O O   . GLY B 2 149 ? 113.398 104.154 144.715 1.00 73.82  ? 144 GLY B O   1 
ATOM 2760 N N   . TYR B 2 150 ? 111.487 105.181 144.148 1.00 73.53  ? 145 TYR B N   1 
ATOM 2761 C CA  . TYR B 2 150 ? 112.097 105.943 143.072 1.00 73.53  ? 145 TYR B CA  1 
ATOM 2762 C C   . TYR B 2 150 ? 112.059 107.435 143.371 1.00 73.53  ? 145 TYR B C   1 
ATOM 2763 O O   . TYR B 2 150 ? 111.057 107.968 143.854 1.00 73.53  ? 145 TYR B O   1 
ATOM 2764 C CB  . TYR B 2 150 ? 111.395 105.645 141.746 1.00 73.53  ? 145 TYR B CB  1 
ATOM 2765 C CG  . TYR B 2 150 ? 109.994 106.195 141.636 1.00 73.53  ? 145 TYR B CG  1 
ATOM 2766 C CD1 . TYR B 2 150 ? 108.913 105.483 142.122 1.00 73.53  ? 145 TYR B CD1 1 
ATOM 2767 C CD2 . TYR B 2 150 ? 109.753 107.424 141.047 1.00 73.53  ? 145 TYR B CD2 1 
ATOM 2768 C CE1 . TYR B 2 150 ? 107.633 105.979 142.028 1.00 73.53  ? 145 TYR B CE1 1 
ATOM 2769 C CE2 . TYR B 2 150 ? 108.475 107.926 140.949 1.00 73.53  ? 145 TYR B CE2 1 
ATOM 2770 C CZ  . TYR B 2 150 ? 107.421 107.200 141.442 1.00 73.53  ? 145 TYR B CZ  1 
ATOM 2771 O OH  . TYR B 2 150 ? 106.144 107.696 141.345 1.00 73.53  ? 145 TYR B OH  1 
ATOM 2772 N N   . LEU B 2 151 ? 113.168 108.108 143.076 1.00 71.00  ? 146 LEU B N   1 
ATOM 2773 C CA  . LEU B 2 151 ? 113.253 109.543 143.298 1.00 71.00  ? 146 LEU B CA  1 
ATOM 2774 C C   . LEU B 2 151 ? 112.382 110.301 142.305 1.00 71.00  ? 146 LEU B C   1 
ATOM 2775 O O   . LEU B 2 151 ? 112.130 109.842 141.188 1.00 71.00  ? 146 LEU B O   1 
ATOM 2776 C CB  . LEU B 2 151 ? 114.697 110.027 143.192 1.00 71.00  ? 146 LEU B CB  1 
ATOM 2777 C CG  . LEU B 2 151 ? 115.621 109.771 144.383 1.00 71.00  ? 146 LEU B CG  1 
ATOM 2778 C CD1 . LEU B 2 151 ? 115.993 108.303 144.524 1.00 71.00  ? 146 LEU B CD1 1 
ATOM 2779 C CD2 . LEU B 2 151 ? 116.863 110.631 144.272 1.00 71.00  ? 146 LEU B CD2 1 
ATOM 2780 N N   . SER B 2 152 ? 111.921 111.478 142.724 1.00 71.59  ? 147 SER B N   1 
ATOM 2781 C CA  . SER B 2 152 ? 111.048 112.281 141.882 1.00 71.59  ? 147 SER B CA  1 
ATOM 2782 C C   . SER B 2 152 ? 111.542 113.716 141.733 1.00 71.59  ? 147 SER B C   1 
ATOM 2783 O O   . SER B 2 152 ? 111.319 114.340 140.691 1.00 71.59  ? 147 SER B O   1 
ATOM 2784 C CB  . SER B 2 152 ? 109.628 112.277 142.438 1.00 71.59  ? 147 SER B CB  1 
ATOM 2785 O OG  . SER B 2 152 ? 108.789 113.098 141.651 1.00 71.59  ? 147 SER B OG  1 
ATOM 2786 N N   . CYS B 2 153 ? 112.209 114.250 142.752 1.00 70.34  ? 148 CYS B N   1 
ATOM 2787 C CA  . CYS B 2 153 ? 112.706 115.616 142.676 1.00 70.34  ? 148 CYS B CA  1 
ATOM 2788 C C   . CYS B 2 153 ? 113.781 115.827 143.730 1.00 70.34  ? 148 CYS B C   1 
ATOM 2789 O O   . CYS B 2 153 ? 113.717 115.262 144.824 1.00 70.34  ? 148 CYS B O   1 
ATOM 2790 C CB  . CYS B 2 153 ? 111.580 116.636 142.862 1.00 70.34  ? 148 CYS B CB  1 
ATOM 2791 S SG  . CYS B 2 153 ? 112.107 118.358 142.713 1.00 70.34  ? 148 CYS B SG  1 
ATOM 2792 N N   . CYS B 2 154 ? 114.769 116.649 143.385 1.00 64.53  ? 149 CYS B N   1 
ATOM 2793 C CA  . CYS B 2 154 ? 115.842 117.018 144.296 1.00 64.53  ? 149 CYS B CA  1 
ATOM 2794 C C   . CYS B 2 154 ? 116.129 118.504 144.161 1.00 64.53  ? 149 CYS B C   1 
ATOM 2795 O O   . CYS B 2 154 ? 116.148 119.039 143.050 1.00 64.53  ? 149 CYS B O   1 
ATOM 2796 C CB  . CYS B 2 154 ? 117.109 116.202 144.021 1.00 64.53  ? 149 CYS B CB  1 
ATOM 2797 S SG  . CYS B 2 154 ? 117.864 116.488 142.411 1.00 64.53  ? 149 CYS B SG  1 
ATOM 2798 N N   . ARG B 2 155 ? 116.349 119.172 145.292 1.00 65.56  ? 150 ARG B N   1 
ATOM 2799 C CA  . ARG B 2 155 ? 116.588 120.607 145.309 1.00 65.56  ? 150 ARG B CA  1 
ATOM 2800 C C   . ARG B 2 155 ? 117.634 120.949 146.360 1.00 65.56  ? 150 ARG B C   1 
ATOM 2801 O O   . ARG B 2 155 ? 117.575 120.457 147.488 1.00 65.56  ? 150 ARG B O   1 
ATOM 2802 C CB  . ARG B 2 155 ? 115.302 121.381 145.590 1.00 65.56  ? 150 ARG B CB  1 
ATOM 2803 C CG  . ARG B 2 155 ? 114.293 121.330 144.463 1.00 65.56  ? 150 ARG B CG  1 
ATOM 2804 C CD  . ARG B 2 155 ? 114.740 122.173 143.290 1.00 65.56  ? 150 ARG B CD  1 
ATOM 2805 N NE  . ARG B 2 155 ? 113.621 122.533 142.427 1.00 65.56  ? 150 ARG B NE  1 
ATOM 2806 C CZ  . ARG B 2 155 ? 113.319 121.908 141.296 1.00 65.56  ? 150 ARG B CZ  1 
ATOM 2807 N NH1 . ARG B 2 155 ? 114.053 120.886 140.882 1.00 65.56  ? 150 ARG B NH1 1 
ATOM 2808 N NH2 . ARG B 2 155 ? 112.280 122.305 140.575 1.00 65.56  ? 150 ARG B NH2 1 
ATOM 2809 N N   . PHE B 2 156 ? 118.586 121.800 145.982 1.00 66.48  ? 151 PHE B N   1 
ATOM 2810 C CA  . PHE B 2 156 ? 119.689 122.176 146.856 1.00 66.48  ? 151 PHE B CA  1 
ATOM 2811 C C   . PHE B 2 156 ? 119.272 123.310 147.782 1.00 66.48  ? 151 PHE B C   1 
ATOM 2812 O O   . PHE B 2 156 ? 118.553 124.226 147.373 1.00 66.48  ? 151 PHE B O   1 
ATOM 2813 C CB  . PHE B 2 156 ? 120.900 122.614 146.032 1.00 66.48  ? 151 PHE B CB  1 
ATOM 2814 C CG  . PHE B 2 156 ? 121.834 121.498 145.671 1.00 66.48  ? 151 PHE B CG  1 
ATOM 2815 C CD1 . PHE B 2 156 ? 122.573 120.853 146.642 1.00 66.48  ? 151 PHE B CD1 1 
ATOM 2816 C CD2 . PHE B 2 156 ? 121.989 121.112 144.357 1.00 66.48  ? 151 PHE B CD2 1 
ATOM 2817 C CE1 . PHE B 2 156 ? 123.436 119.831 146.305 1.00 66.48  ? 151 PHE B CE1 1 
ATOM 2818 C CE2 . PHE B 2 156 ? 122.846 120.094 144.015 1.00 66.48  ? 151 PHE B CE2 1 
ATOM 2819 C CZ  . PHE B 2 156 ? 123.571 119.454 144.986 1.00 66.48  ? 151 PHE B CZ  1 
ATOM 2820 N N   . LEU B 2 157 ? 119.721 123.243 149.036 1.00 68.63  ? 152 LEU B N   1 
ATOM 2821 C CA  . LEU B 2 157 ? 119.555 124.346 149.979 1.00 68.63  ? 152 LEU B CA  1 
ATOM 2822 C C   . LEU B 2 157 ? 120.788 125.242 150.005 1.00 68.63  ? 152 LEU B C   1 
ATOM 2823 O O   . LEU B 2 157 ? 120.708 126.436 149.710 1.00 68.63  ? 152 LEU B O   1 
ATOM 2824 C CB  . LEU B 2 157 ? 119.263 123.810 151.385 1.00 68.63  ? 152 LEU B CB  1 
ATOM 2825 C CG  . LEU B 2 157 ? 117.835 123.372 151.694 1.00 68.63  ? 152 LEU B CG  1 
ATOM 2826 C CD1 . LEU B 2 157 ? 117.806 122.508 152.936 1.00 68.63  ? 152 LEU B CD1 1 
ATOM 2827 C CD2 . LEU B 2 157 ? 116.945 124.581 151.866 1.00 68.63  ? 152 LEU B CD2 1 
ATOM 2828 N N   . ASP B 2 158 ? 121.928 124.676 150.364 1.00 73.67  ? 153 ASP B N   1 
ATOM 2829 C CA  . ASP B 2 158 ? 123.238 125.288 150.215 1.00 73.67  ? 153 ASP B CA  1 
ATOM 2830 C C   . ASP B 2 158 ? 124.135 124.288 149.492 1.00 73.67  ? 153 ASP B C   1 
ATOM 2831 O O   . ASP B 2 158 ? 123.666 123.283 148.950 1.00 73.67  ? 153 ASP B O   1 
ATOM 2832 C CB  . ASP B 2 158 ? 123.806 125.710 151.570 1.00 73.67  ? 153 ASP B CB  1 
ATOM 2833 C CG  . ASP B 2 158 ? 123.769 124.593 152.590 1.00 73.67  ? 153 ASP B CG  1 
ATOM 2834 O OD1 . ASP B 2 158 ? 123.353 123.474 152.230 1.00 73.67  ? 153 ASP B OD1 1 
ATOM 2835 O OD2 . ASP B 2 158 ? 124.158 124.833 153.753 1.00 73.67  ? 153 ASP B OD2 1 
ATOM 2836 N N   . ASP B 2 159 ? 125.436 124.564 149.478 1.00 72.90  ? 154 ASP B N   1 
ATOM 2837 C CA  . ASP B 2 159 ? 126.352 123.661 148.795 1.00 72.90  ? 154 ASP B CA  1 
ATOM 2838 C C   . ASP B 2 159 ? 126.643 122.396 149.589 1.00 72.90  ? 154 ASP B C   1 
ATOM 2839 O O   . ASP B 2 159 ? 127.447 121.578 149.134 1.00 72.90  ? 154 ASP B O   1 
ATOM 2840 C CB  . ASP B 2 159 ? 127.661 124.380 148.479 1.00 72.90  ? 154 ASP B CB  1 
ATOM 2841 C CG  . ASP B 2 159 ? 127.527 125.356 147.333 1.00 72.90  ? 154 ASP B CG  1 
ATOM 2842 O OD1 . ASP B 2 159 ? 126.383 125.727 146.998 1.00 72.90  ? 154 ASP B OD1 1 
ATOM 2843 O OD2 . ASP B 2 159 ? 128.566 125.752 146.766 1.00 72.90  ? 154 ASP B OD2 1 
ATOM 2844 N N   . ASN B 2 160 ? 126.018 122.209 150.754 1.00 73.46  ? 155 ASN B N   1 
ATOM 2845 C CA  . ASN B 2 160 ? 126.327 121.075 151.610 1.00 73.46  ? 155 ASN B CA  1 
ATOM 2846 C C   . ASN B 2 160 ? 125.088 120.276 152.018 1.00 73.46  ? 155 ASN B C   1 
ATOM 2847 O O   . ASN B 2 160 ? 125.231 119.221 152.642 1.00 73.46  ? 155 ASN B O   1 
ATOM 2848 C CB  . ASN B 2 160 ? 127.070 121.567 152.865 1.00 73.46  ? 155 ASN B CB  1 
ATOM 2849 C CG  . ASN B 2 160 ? 127.740 120.448 153.649 1.00 73.46  ? 155 ASN B CG  1 
ATOM 2850 O OD1 . ASN B 2 160 ? 127.679 119.278 153.281 1.00 73.46  ? 155 ASN B OD1 1 
ATOM 2851 N ND2 . ASN B 2 160 ? 128.389 120.815 154.746 1.00 73.46  ? 155 ASN B ND2 1 
ATOM 2852 N N   . GLN B 2 161 ? 123.884 120.725 151.665 1.00 70.83  ? 156 GLN B N   1 
ATOM 2853 C CA  . GLN B 2 161 ? 122.661 120.000 151.986 1.00 70.83  ? 156 GLN B CA  1 
ATOM 2854 C C   . GLN B 2 161 ? 121.816 119.824 150.731 1.00 70.83  ? 156 GLN B C   1 
ATOM 2855 O O   . GLN B 2 161 ? 122.036 120.482 149.711 1.00 70.83  ? 156 GLN B O   1 
ATOM 2856 C CB  . GLN B 2 161 ? 121.848 120.716 153.070 1.00 70.83  ? 156 GLN B CB  1 
ATOM 2857 C CG  . GLN B 2 161 ? 122.668 121.199 154.249 1.00 70.83  ? 156 GLN B CG  1 
ATOM 2858 C CD  . GLN B 2 161 ? 121.813 121.782 155.352 1.00 70.83  ? 156 GLN B CD  1 
ATOM 2859 O OE1 . GLN B 2 161 ? 122.030 122.910 155.789 1.00 70.83  ? 156 GLN B OE1 1 
ATOM 2860 N NE2 . GLN B 2 161 ? 120.837 121.014 155.812 1.00 70.83  ? 156 GLN B NE2 1 
ATOM 2861 N N   . ILE B 2 162 ? 120.836 118.923 150.818 1.00 68.51  ? 157 ILE B N   1 
ATOM 2862 C CA  . ILE B 2 162 ? 119.972 118.592 149.690 1.00 68.51  ? 157 ILE B CA  1 
ATOM 2863 C C   . ILE B 2 162 ? 118.733 117.879 150.218 1.00 68.51  ? 157 ILE B C   1 
ATOM 2864 O O   . ILE B 2 162 ? 118.794 117.140 151.204 1.00 68.51  ? 157 ILE B O   1 
ATOM 2865 C CB  . ILE B 2 162 ? 120.725 117.738 148.644 1.00 68.51  ? 157 ILE B CB  1 
ATOM 2866 C CG1 . ILE B 2 162 ? 119.888 117.551 147.383 1.00 68.51  ? 157 ILE B CG1 1 
ATOM 2867 C CG2 . ILE B 2 162 ? 121.120 116.398 149.223 1.00 68.51  ? 157 ILE B CG2 1 
ATOM 2868 C CD1 . ILE B 2 162 ? 120.642 116.893 146.252 1.00 68.51  ? 157 ILE B CD1 1 
ATOM 2869 N N   . VAL B 2 163 ? 117.599 118.112 149.559 1.00 66.21  ? 158 VAL B N   1 
ATOM 2870 C CA  . VAL B 2 163 ? 116.312 117.538 149.940 1.00 66.21  ? 158 VAL B CA  1 
ATOM 2871 C C   . VAL B 2 163 ? 115.770 116.746 148.759 1.00 66.21  ? 158 VAL B C   1 
ATOM 2872 O O   . VAL B 2 163 ? 115.774 117.240 147.625 1.00 66.21  ? 158 VAL B O   1 
ATOM 2873 C CB  . VAL B 2 163 ? 115.312 118.624 150.368 1.00 66.21  ? 158 VAL B CB  1 
ATOM 2874 C CG1 . VAL B 2 163 ? 113.971 118.006 150.693 1.00 66.21  ? 158 VAL B CG1 1 
ATOM 2875 C CG2 . VAL B 2 163 ? 115.848 119.392 151.558 1.00 66.21  ? 158 VAL B CG2 1 
ATOM 2876 N N   . THR B 2 164 ? 115.303 115.525 149.019 1.00 69.52  ? 159 THR B N   1 
ATOM 2877 C CA  . THR B 2 164 ? 114.911 114.608 147.957 1.00 69.52  ? 159 THR B CA  1 
ATOM 2878 C C   . THR B 2 164 ? 113.498 114.084 148.182 1.00 69.52  ? 159 THR B C   1 
ATOM 2879 O O   . THR B 2 164 ? 112.913 114.236 149.256 1.00 69.52  ? 159 THR B O   1 
ATOM 2880 C CB  . THR B 2 164 ? 115.878 113.425 147.845 1.00 69.52  ? 159 THR B CB  1 
ATOM 2881 O OG1 . THR B 2 164 ? 115.934 112.729 149.095 1.00 69.52  ? 159 THR B OG1 1 
ATOM 2882 C CG2 . THR B 2 164 ? 117.268 113.905 147.480 1.00 69.52  ? 159 THR B CG2 1 
ATOM 2883 N N   . SER B 2 165 ? 112.962 113.461 147.133 1.00 74.05  ? 160 SER B N   1 
ATOM 2884 C CA  . SER B 2 165 ? 111.659 112.807 147.137 1.00 74.05  ? 160 SER B CA  1 
ATOM 2885 C C   . SER B 2 165 ? 111.852 111.359 146.727 1.00 74.05  ? 160 SER B C   1 
ATOM 2886 O O   . SER B 2 165 ? 112.819 111.038 146.029 1.00 74.05  ? 160 SER B O   1 
ATOM 2887 C CB  . SER B 2 165 ? 110.691 113.480 146.173 1.00 74.05  ? 160 SER B CB  1 
ATOM 2888 O OG  . SER B 2 165 ? 109.491 112.740 146.057 1.00 74.05  ? 160 SER B OG  1 
ATOM 2889 N N   . SER B 2 166 ? 110.948 110.485 147.160 1.00 76.27  ? 161 SER B N   1 
ATOM 2890 C CA  . SER B 2 166 ? 111.098 109.063 146.904 1.00 76.27  ? 161 SER B CA  1 
ATOM 2891 C C   . SER B 2 166 ? 109.761 108.439 146.534 1.00 76.27  ? 161 SER B C   1 
ATOM 2892 O O   . SER B 2 166 ? 108.693 109.008 146.766 1.00 76.27  ? 161 SER B O   1 
ATOM 2893 C CB  . SER B 2 166 ? 111.697 108.345 148.115 1.00 76.27  ? 161 SER B CB  1 
ATOM 2894 O OG  . SER B 2 166 ? 111.937 106.977 147.829 1.00 76.27  ? 161 SER B OG  1 
ATOM 2895 N N   . GLY B 2 167 ? 109.839 107.249 145.940 1.00 77.49  ? 162 GLY B N   1 
ATOM 2896 C CA  . GLY B 2 167 ? 108.627 106.524 145.595 1.00 77.49  ? 162 GLY B CA  1 
ATOM 2897 C C   . GLY B 2 167 ? 107.835 106.113 146.819 1.00 77.49  ? 162 GLY B C   1 
ATOM 2898 O O   . GLY B 2 167 ? 106.617 106.296 146.876 1.00 77.49  ? 162 GLY B O   1 
ATOM 2899 N N   . ASP B 2 168 ? 108.514 105.552 147.815 1.00 78.29  ? 163 ASP B N   1 
ATOM 2900 C CA  . ASP B 2 168 ? 107.855 105.268 149.076 1.00 78.29  ? 163 ASP B CA  1 
ATOM 2901 C C   . ASP B 2 168 ? 107.519 106.573 149.784 1.00 78.29  ? 163 ASP B C   1 
ATOM 2902 O O   . ASP B 2 168 ? 108.139 107.616 149.557 1.00 78.29  ? 163 ASP B O   1 
ATOM 2903 C CB  . ASP B 2 168 ? 108.727 104.383 149.963 1.00 78.29  ? 163 ASP B CB  1 
ATOM 2904 C CG  . ASP B 2 168 ? 110.127 104.918 150.118 1.00 78.29  ? 163 ASP B CG  1 
ATOM 2905 O OD1 . ASP B 2 168 ? 110.501 105.820 149.349 1.00 78.29  ? 163 ASP B OD1 1 
ATOM 2906 O OD2 . ASP B 2 168 ? 110.855 104.437 151.011 1.00 78.29  ? 163 ASP B OD2 1 
ATOM 2907 N N   . THR B 2 169 ? 106.519 106.507 150.658 1.00 80.79  ? 164 THR B N   1 
ATOM 2908 C CA  . THR B 2 169 ? 105.933 107.724 151.219 1.00 80.79  ? 164 THR B CA  1 
ATOM 2909 C C   . THR B 2 169 ? 107.011 108.155 152.200 1.00 80.79  ? 164 THR B C   1 
ATOM 2910 O O   . THR B 2 169 ? 107.025 107.699 153.347 1.00 80.79  ? 164 THR B O   1 
ATOM 2911 C CB  . THR B 2 169 ? 104.601 107.398 151.885 1.00 80.79  ? 164 THR B CB  1 
ATOM 2912 O OG1 . THR B 2 169 ? 104.842 106.784 153.156 1.00 80.79  ? 164 THR B OG1 1 
ATOM 2913 C CG2 . THR B 2 169 ? 103.800 106.437 151.024 1.00 80.79  ? 164 THR B CG2 1 
ATOM 2914 N N   . THR B 2 170 ? 107.903 109.047 151.773 1.00 78.69  ? 165 THR B N   1 
ATOM 2915 C CA  . THR B 2 170 ? 108.987 109.518 152.627 1.00 78.69  ? 165 THR B CA  1 
ATOM 2916 C C   . THR B 2 170 ? 109.713 110.618 151.870 1.00 78.69  ? 165 THR B C   1 
ATOM 2917 O O   . THR B 2 170 ? 109.859 110.566 150.646 1.00 78.69  ? 165 THR B O   1 
ATOM 2918 C CB  . THR B 2 170 ? 110.023 108.511 153.152 1.00 78.69  ? 165 THR B CB  1 
ATOM 2919 O OG1 . THR B 2 170 ? 110.422 107.629 152.095 1.00 78.69  ? 165 THR B OG1 1 
ATOM 2920 C CG2 . THR B 2 170 ? 109.462 107.702 154.312 1.00 78.69  ? 165 THR B CG2 1 
ATOM 2921 N N   . CYS B 2 171 ? 110.167 111.618 152.620 1.00 78.28  ? 166 CYS B N   1 
ATOM 2922 C CA  . CYS B 2 171 ? 111.055 112.656 152.121 1.00 78.28  ? 166 CYS B CA  1 
ATOM 2923 C C   . CYS B 2 171 ? 112.186 112.839 153.120 1.00 78.28  ? 166 CYS B C   1 
ATOM 2924 O O   . CYS B 2 171 ? 111.996 112.672 154.327 1.00 78.28  ? 166 CYS B O   1 
ATOM 2925 C CB  . CYS B 2 171 ? 110.320 113.979 151.905 1.00 78.28  ? 166 CYS B CB  1 
ATOM 2926 S SG  . CYS B 2 171 ? 108.950 113.890 150.741 1.00 78.28  ? 166 CYS B SG  1 
ATOM 2927 N N   . ALA B 2 172 ? 113.369 113.178 152.614 1.00 74.14  ? 167 ALA B N   1 
ATOM 2928 C CA  . ALA B 2 172 ? 114.568 113.158 153.436 1.00 74.14  ? 167 ALA B CA  1 
ATOM 2929 C C   . ALA B 2 172 ? 115.403 114.407 153.203 1.00 74.14  ? 167 ALA B C   1 
ATOM 2930 O O   . ALA B 2 172 ? 115.258 115.103 152.196 1.00 74.14  ? 167 ALA B O   1 
ATOM 2931 C CB  . ALA B 2 172 ? 115.415 111.913 153.155 1.00 74.14  ? 167 ALA B CB  1 
ATOM 2932 N N   . LEU B 2 173 ? 116.287 114.676 154.159 1.00 71.68  ? 168 LEU B N   1 
ATOM 2933 C CA  . LEU B 2 173 ? 117.287 115.730 154.064 1.00 71.68  ? 168 LEU B CA  1 
ATOM 2934 C C   . LEU B 2 173 ? 118.652 115.104 154.297 1.00 71.68  ? 168 LEU B C   1 
ATOM 2935 O O   . LEU B 2 173 ? 118.816 114.296 155.217 1.00 71.68  ? 168 LEU B O   1 
ATOM 2936 C CB  . LEU B 2 173 ? 117.022 116.839 155.081 1.00 71.68  ? 168 LEU B CB  1 
ATOM 2937 C CG  . LEU B 2 173 ? 118.159 117.821 155.345 1.00 71.68  ? 168 LEU B CG  1 
ATOM 2938 C CD1 . LEU B 2 173 ? 118.474 118.628 154.101 1.00 71.68  ? 168 LEU B CD1 1 
ATOM 2939 C CD2 . LEU B 2 173 ? 117.804 118.736 156.498 1.00 71.68  ? 168 LEU B CD2 1 
ATOM 2940 N N   . TRP B 2 174 ? 119.621 115.455 153.459 1.00 71.09  ? 169 TRP B N   1 
ATOM 2941 C CA  . TRP B 2 174 ? 120.917 114.797 153.458 1.00 71.09  ? 169 TRP B CA  1 
ATOM 2942 C C   . TRP B 2 174 ? 122.038 115.766 153.809 1.00 71.09  ? 169 TRP B C   1 
ATOM 2943 O O   . TRP B 2 174 ? 121.869 116.988 153.809 1.00 71.09  ? 169 TRP B O   1 
ATOM 2944 C CB  . TRP B 2 174 ? 121.215 114.169 152.094 1.00 71.09  ? 169 TRP B CB  1 
ATOM 2945 C CG  . TRP B 2 174 ? 120.247 113.126 151.672 1.00 71.09  ? 169 TRP B CG  1 
ATOM 2946 C CD1 . TRP B 2 174 ? 119.013 113.325 151.139 1.00 71.09  ? 169 TRP B CD1 1 
ATOM 2947 C CD2 . TRP B 2 174 ? 120.437 111.712 151.729 1.00 71.09  ? 169 TRP B CD2 1 
ATOM 2948 N NE1 . TRP B 2 174 ? 118.416 112.122 150.866 1.00 71.09  ? 169 TRP B NE1 1 
ATOM 2949 C CE2 . TRP B 2 174 ? 119.272 111.114 151.220 1.00 71.09  ? 169 TRP B CE2 1 
ATOM 2950 C CE3 . TRP B 2 174 ? 121.478 110.891 152.168 1.00 71.09  ? 169 TRP B CE3 1 
ATOM 2951 C CZ2 . TRP B 2 174 ? 119.118 109.738 151.137 1.00 71.09  ? 169 TRP B CZ2 1 
ATOM 2952 C CZ3 . TRP B 2 174 ? 121.323 109.525 152.083 1.00 71.09  ? 169 TRP B CZ3 1 
ATOM 2953 C CH2 . TRP B 2 174 ? 120.151 108.962 151.571 1.00 71.09  ? 169 TRP B CH2 1 
ATOM 2954 N N   . ASP B 2 175 ? 123.192 115.185 154.114 1.00 71.75  ? 170 ASP B N   1 
ATOM 2955 C CA  . ASP B 2 175 ? 124.456 115.894 154.214 1.00 71.75  ? 170 ASP B CA  1 
ATOM 2956 C C   . ASP B 2 175 ? 125.379 115.360 153.128 1.00 71.75  ? 170 ASP B C   1 
ATOM 2957 O O   . ASP B 2 175 ? 125.380 114.159 152.844 1.00 71.75  ? 170 ASP B O   1 
ATOM 2958 C CB  . ASP B 2 175 ? 125.078 115.709 155.600 1.00 71.75  ? 170 ASP B CB  1 
ATOM 2959 C CG  . ASP B 2 175 ? 126.339 116.525 155.795 1.00 71.75  ? 170 ASP B CG  1 
ATOM 2960 O OD1 . ASP B 2 175 ? 127.331 116.292 155.074 1.00 71.75  ? 170 ASP B OD1 1 
ATOM 2961 O OD2 . ASP B 2 175 ? 126.338 117.405 156.681 1.00 71.75  ? 170 ASP B OD2 1 
ATOM 2962 N N   . ILE B 2 176 ? 126.148 116.247 152.506 1.00 70.26  ? 171 ILE B N   1 
ATOM 2963 C CA  . ILE B 2 176 ? 126.958 115.839 151.363 1.00 70.26  ? 171 ILE B CA  1 
ATOM 2964 C C   . ILE B 2 176 ? 128.338 115.355 151.793 1.00 70.26  ? 171 ILE B C   1 
ATOM 2965 O O   . ILE B 2 176 ? 128.858 114.387 151.235 1.00 70.26  ? 171 ILE B O   1 
ATOM 2966 C CB  . ILE B 2 176 ? 127.055 116.989 150.343 1.00 70.26  ? 171 ILE B CB  1 
ATOM 2967 C CG1 . ILE B 2 176 ? 125.671 117.319 149.791 1.00 70.26  ? 171 ILE B CG1 1 
ATOM 2968 C CG2 . ILE B 2 176 ? 127.990 116.619 149.207 1.00 70.26  ? 171 ILE B CG2 1 
ATOM 2969 C CD1 . ILE B 2 176 ? 125.628 118.592 148.982 1.00 70.26  ? 171 ILE B CD1 1 
ATOM 2970 N N   . GLU B 2 177 ? 128.962 116.008 152.774 1.00 71.47  ? 172 GLU B N   1 
ATOM 2971 C CA  . GLU B 2 177 ? 130.264 115.546 153.247 1.00 71.47  ? 172 GLU B CA  1 
ATOM 2972 C C   . GLU B 2 177 ? 130.156 114.161 153.876 1.00 71.47  ? 172 GLU B C   1 
ATOM 2973 O O   . GLU B 2 177 ? 130.888 113.238 153.503 1.00 71.47  ? 172 GLU B O   1 
ATOM 2974 C CB  . GLU B 2 177 ? 130.848 116.550 154.240 1.00 71.47  ? 172 GLU B CB  1 
ATOM 2975 N N   . THR B 2 178 ? 129.239 113.998 154.825 1.00 73.03  ? 173 THR B N   1 
ATOM 2976 C CA  . THR B 2 178 ? 128.919 112.700 155.404 1.00 73.03  ? 173 THR B CA  1 
ATOM 2977 C C   . THR B 2 178 ? 127.605 112.224 154.800 1.00 73.03  ? 173 THR B C   1 
ATOM 2978 O O   . THR B 2 178 ? 126.574 112.888 154.951 1.00 73.03  ? 173 THR B O   1 
ATOM 2979 C CB  . THR B 2 178 ? 128.810 112.787 156.926 1.00 73.03  ? 173 THR B CB  1 
ATOM 2980 N N   . GLY B 2 179 ? 127.638 111.071 154.138 1.00 72.94  ? 174 GLY B N   1 
ATOM 2981 C CA  . GLY B 2 179 ? 126.516 110.646 153.319 1.00 72.94  ? 174 GLY B CA  1 
ATOM 2982 C C   . GLY B 2 179 ? 125.299 110.180 154.088 1.00 72.94  ? 174 GLY B C   1 
ATOM 2983 O O   . GLY B 2 179 ? 124.299 109.818 153.460 1.00 72.94  ? 174 GLY B O   1 
ATOM 2984 N N   . GLN B 2 180 ? 125.356 110.174 155.415 1.00 72.81  ? 175 GLN B N   1 
ATOM 2985 C CA  . GLN B 2 180 ? 124.241 109.674 156.202 1.00 72.81  ? 175 GLN B CA  1 
ATOM 2986 C C   . GLN B 2 180 ? 123.074 110.655 156.191 1.00 72.81  ? 175 GLN B C   1 
ATOM 2987 O O   . GLN B 2 180 ? 123.249 111.865 156.030 1.00 72.81  ? 175 GLN B O   1 
ATOM 2988 C CB  . GLN B 2 180 ? 124.684 109.409 157.641 1.00 72.81  ? 175 GLN B CB  1 
ATOM 2989 N N   . GLN B 2 181 ? 121.871 110.114 156.359 1.00 73.84  ? 176 GLN B N   1 
ATOM 2990 C CA  . GLN B 2 181 ? 120.688 110.944 156.529 1.00 73.84  ? 176 GLN B CA  1 
ATOM 2991 C C   . GLN B 2 181 ? 120.776 111.722 157.835 1.00 73.84  ? 176 GLN B C   1 
ATOM 2992 O O   . GLN B 2 181 ? 121.434 111.295 158.787 1.00 73.84  ? 176 GLN B O   1 
ATOM 2993 C CB  . GLN B 2 181 ? 119.431 110.075 156.529 1.00 73.84  ? 176 GLN B CB  1 
ATOM 2994 C CG  . GLN B 2 181 ? 119.129 109.395 155.211 1.00 73.84  ? 176 GLN B CG  1 
ATOM 2995 C CD  . GLN B 2 181 ? 117.700 108.898 155.131 1.00 73.84  ? 176 GLN B CD  1 
ATOM 2996 O OE1 . GLN B 2 181 ? 116.761 109.686 155.040 1.00 73.84  ? 176 GLN B OE1 1 
ATOM 2997 N NE2 . GLN B 2 181 ? 117.527 107.584 155.164 1.00 73.84  ? 176 GLN B NE2 1 
ATOM 2998 N N   . THR B 2 182 ? 120.110 112.873 157.883 1.00 72.70  ? 177 THR B N   1 
ATOM 2999 C CA  . THR B 2 182 ? 120.058 113.654 159.111 1.00 72.70  ? 177 THR B CA  1 
ATOM 3000 C C   . THR B 2 182 ? 118.658 113.766 159.693 1.00 72.70  ? 177 THR B C   1 
ATOM 3001 O O   . THR B 2 182 ? 118.521 113.988 160.899 1.00 72.70  ? 177 THR B O   1 
ATOM 3002 C CB  . THR B 2 182 ? 120.617 115.063 158.884 1.00 72.70  ? 177 THR B CB  1 
ATOM 3003 O OG1 . THR B 2 182 ? 120.561 115.802 160.109 1.00 72.70  ? 177 THR B OG1 1 
ATOM 3004 C CG2 . THR B 2 182 ? 119.816 115.796 157.831 1.00 72.70  ? 177 THR B CG2 1 
ATOM 3005 N N   . THR B 2 183 ? 117.622 113.620 158.873 1.00 76.11  ? 178 THR B N   1 
ATOM 3006 C CA  . THR B 2 183 ? 116.244 113.635 159.341 1.00 76.11  ? 178 THR B CA  1 
ATOM 3007 C C   . THR B 2 183 ? 115.378 113.001 158.264 1.00 76.11  ? 178 THR B C   1 
ATOM 3008 O O   . THR B 2 183 ? 115.642 113.159 157.070 1.00 76.11  ? 178 THR B O   1 
ATOM 3009 C CB  . THR B 2 183 ? 115.753 115.058 159.647 1.00 76.11  ? 178 THR B CB  1 
ATOM 3010 O OG1 . THR B 2 183 ? 116.702 115.734 160.479 1.00 76.11  ? 178 THR B OG1 1 
ATOM 3011 C CG2 . THR B 2 183 ? 114.415 115.022 160.360 1.00 76.11  ? 178 THR B CG2 1 
ATOM 3012 N N   . THR B 2 184 ? 114.344 112.286 158.695 1.00 77.44  ? 179 THR B N   1 
ATOM 3013 C CA  . THR B 2 184 ? 113.402 111.661 157.782 1.00 77.44  ? 179 THR B CA  1 
ATOM 3014 C C   . THR B 2 184 ? 111.995 112.168 158.067 1.00 77.44  ? 179 THR B C   1 
ATOM 3015 O O   . THR B 2 184 ? 111.619 112.404 159.219 1.00 77.44  ? 179 THR B O   1 
ATOM 3016 C CB  . THR B 2 184 ? 113.444 110.133 157.881 1.00 77.44  ? 179 THR B CB  1 
ATOM 3017 O OG1 . THR B 2 184 ? 112.484 109.570 156.981 1.00 77.44  ? 179 THR B OG1 1 
ATOM 3018 C CG2 . THR B 2 184 ? 113.142 109.672 159.300 1.00 77.44  ? 179 THR B CG2 1 
ATOM 3019 N N   . PHE B 2 185 ? 111.225 112.351 156.999 1.00 78.64  ? 180 PHE B N   1 
ATOM 3020 C CA  . PHE B 2 185 ? 109.885 112.911 157.073 1.00 78.64  ? 180 PHE B CA  1 
ATOM 3021 C C   . PHE B 2 185 ? 108.877 111.852 156.652 1.00 78.64  ? 180 PHE B C   1 
ATOM 3022 O O   . PHE B 2 185 ? 109.006 111.262 155.574 1.00 78.64  ? 180 PHE B O   1 
ATOM 3023 C CB  . PHE B 2 185 ? 109.769 114.148 156.181 1.00 78.64  ? 180 PHE B CB  1 
ATOM 3024 C CG  . PHE B 2 185 ? 110.757 115.231 156.509 1.00 78.64  ? 180 PHE B CG  1 
ATOM 3025 C CD1 . PHE B 2 185 ? 110.614 115.996 157.649 1.00 78.64  ? 180 PHE B CD1 1 
ATOM 3026 C CD2 . PHE B 2 185 ? 111.817 115.496 155.665 1.00 78.64  ? 180 PHE B CD2 1 
ATOM 3027 C CE1 . PHE B 2 185 ? 111.519 116.994 157.944 1.00 78.64  ? 180 PHE B CE1 1 
ATOM 3028 C CE2 . PHE B 2 185 ? 112.721 116.493 155.957 1.00 78.64  ? 180 PHE B CE2 1 
ATOM 3029 C CZ  . PHE B 2 185 ? 112.572 117.241 157.096 1.00 78.64  ? 180 PHE B CZ  1 
ATOM 3030 N N   . THR B 2 186 ? 107.878 111.611 157.500 1.00 77.39  ? 181 THR B N   1 
ATOM 3031 C CA  . THR B 2 186 ? 106.894 110.564 157.272 1.00 77.39  ? 181 THR B CA  1 
ATOM 3032 C C   . THR B 2 186 ? 105.493 111.098 157.533 1.00 77.39  ? 181 THR B C   1 
ATOM 3033 O O   . THR B 2 186 ? 105.305 112.075 158.261 1.00 77.39  ? 181 THR B O   1 
ATOM 3034 C CB  . THR B 2 186 ? 107.148 109.339 158.160 1.00 77.39  ? 181 THR B CB  1 
ATOM 3035 O OG1 . THR B 2 186 ? 107.205 109.745 159.533 1.00 77.39  ? 181 THR B OG1 1 
ATOM 3036 C CG2 . THR B 2 186 ? 108.454 108.660 157.783 1.00 77.39  ? 181 THR B CG2 1 
ATOM 3037 N N   . GLY B 2 187 ? 104.506 110.439 156.933 1.00 76.27  ? 182 GLY B N   1 
ATOM 3038 C CA  . GLY B 2 187 ? 103.125 110.822 157.147 1.00 76.27  ? 182 GLY B CA  1 
ATOM 3039 C C   . GLY B 2 187 ? 102.212 110.682 155.948 1.00 76.27  ? 182 GLY B C   1 
ATOM 3040 O O   . GLY B 2 187 ? 100.989 110.756 156.091 1.00 76.27  ? 182 GLY B O   1 
ATOM 3041 N N   . HIS B 2 188 ? 102.777 110.479 154.763 1.00 77.03  ? 183 HIS B N   1 
ATOM 3042 C CA  . HIS B 2 188 ? 101.955 110.329 153.573 1.00 77.03  ? 183 HIS B CA  1 
ATOM 3043 C C   . HIS B 2 188 ? 101.425 108.901 153.462 1.00 77.03  ? 183 HIS B C   1 
ATOM 3044 O O   . HIS B 2 188 ? 101.777 108.014 154.243 1.00 77.03  ? 183 HIS B O   1 
ATOM 3045 C CB  . HIS B 2 188 ? 102.749 110.696 152.324 1.00 77.03  ? 183 HIS B CB  1 
ATOM 3046 C CG  . HIS B 2 188 ? 102.683 112.147 151.967 1.00 77.03  ? 183 HIS B CG  1 
ATOM 3047 N ND1 . HIS B 2 188 ? 101.629 112.695 151.271 1.00 77.03  ? 183 HIS B ND1 1 
ATOM 3048 C CD2 . HIS B 2 188 ? 103.546 113.162 152.204 1.00 77.03  ? 183 HIS B CD2 1 
ATOM 3049 C CE1 . HIS B 2 188 ? 101.843 113.986 151.097 1.00 77.03  ? 183 HIS B CE1 1 
ATOM 3050 N NE2 . HIS B 2 188 ? 102.999 114.294 151.654 1.00 77.03  ? 183 HIS B NE2 1 
ATOM 3051 N N   . THR B 2 189 ? 100.564 108.684 152.467 1.00 80.02  ? 184 THR B N   1 
ATOM 3052 C CA  . THR B 2 189 ? 100.000 107.368 152.197 1.00 80.02  ? 184 THR B CA  1 
ATOM 3053 C C   . THR B 2 189 ? 100.171 106.918 150.754 1.00 80.02  ? 184 THR B C   1 
ATOM 3054 O O   . THR B 2 189 ? 99.662  105.851 150.394 1.00 80.02  ? 184 THR B O   1 
ATOM 3055 C CB  . THR B 2 189 ? 98.507  107.335 152.550 1.00 80.02  ? 184 THR B CB  1 
ATOM 3056 O OG1 . THR B 2 189 ? 97.795  108.241 151.701 1.00 80.02  ? 184 THR B OG1 1 
ATOM 3057 C CG2 . THR B 2 189 ? 98.285  107.721 154.001 1.00 80.02  ? 184 THR B CG2 1 
ATOM 3058 N N   . GLY B 2 190 ? 100.866 107.687 149.919 1.00 82.26  ? 185 GLY B N   1 
ATOM 3059 C CA  . GLY B 2 190 ? 101.075 107.325 148.534 1.00 82.26  ? 185 GLY B CA  1 
ATOM 3060 C C   . GLY B 2 190 ? 102.358 107.935 148.013 1.00 82.26  ? 185 GLY B C   1 
ATOM 3061 O O   . GLY B 2 190 ? 103.090 108.608 148.742 1.00 82.26  ? 185 GLY B O   1 
ATOM 3062 N N   . ASP B 2 191 ? 102.629 107.690 146.733 1.00 81.22  ? 186 ASP B N   1 
ATOM 3063 C CA  . ASP B 2 191 ? 103.852 108.192 146.124 1.00 81.22  ? 186 ASP B CA  1 
ATOM 3064 C C   . ASP B 2 191 ? 103.864 109.715 146.110 1.00 81.22  ? 186 ASP B C   1 
ATOM 3065 O O   . ASP B 2 191 ? 102.873 110.355 145.752 1.00 81.22  ? 186 ASP B O   1 
ATOM 3066 C CB  . ASP B 2 191 ? 103.991 107.659 144.700 1.00 81.22  ? 186 ASP B CB  1 
ATOM 3067 C CG  . ASP B 2 191 ? 104.014 106.150 144.644 1.00 81.22  ? 186 ASP B CG  1 
ATOM 3068 O OD1 . ASP B 2 191 ? 103.775 105.513 145.690 1.00 81.22  ? 186 ASP B OD1 1 
ATOM 3069 O OD2 . ASP B 2 191 ? 104.269 105.599 143.554 1.00 81.22  ? 186 ASP B OD2 1 
ATOM 3070 N N   . VAL B 2 192 ? 105.001 110.294 146.486 1.00 77.16  ? 187 VAL B N   1 
ATOM 3071 C CA  . VAL B 2 192 ? 105.191 111.740 146.502 1.00 77.16  ? 187 VAL B CA  1 
ATOM 3072 C C   . VAL B 2 192 ? 106.013 112.133 145.283 1.00 77.16  ? 187 VAL B C   1 
ATOM 3073 O O   . VAL B 2 192 ? 106.988 111.453 144.936 1.00 77.16  ? 187 VAL B O   1 
ATOM 3074 C CB  . VAL B 2 192 ? 105.849 112.201 147.815 1.00 77.16  ? 187 VAL B CB  1 
ATOM 3075 C CG1 . VAL B 2 192 ? 107.252 111.648 147.951 1.00 77.16  ? 187 VAL B CG1 1 
ATOM 3076 C CG2 . VAL B 2 192 ? 105.864 113.720 147.896 1.00 77.16  ? 187 VAL B CG2 1 
ATOM 3077 N N   . MET B 2 193 ? 105.602 113.208 144.604 1.00 78.16  ? 188 MET B N   1 
ATOM 3078 C CA  . MET B 2 193 ? 106.132 113.503 143.281 1.00 78.16  ? 188 MET B CA  1 
ATOM 3079 C C   . MET B 2 193 ? 106.549 114.945 143.019 1.00 78.16  ? 188 MET B C   1 
ATOM 3080 O O   . MET B 2 193 ? 106.888 115.254 141.872 1.00 78.16  ? 188 MET B O   1 
ATOM 3081 C CB  . MET B 2 193 ? 105.114 113.112 142.201 1.00 78.16  ? 188 MET B CB  1 
ATOM 3082 C CG  . MET B 2 193 ? 104.856 111.632 142.085 1.00 78.16  ? 188 MET B CG  1 
ATOM 3083 S SD  . MET B 2 193 ? 103.595 111.305 140.849 1.00 78.16  ? 188 MET B SD  1 
ATOM 3084 C CE  . MET B 2 193 ? 104.489 111.712 139.352 1.00 78.16  ? 188 MET B CE  1 
ATOM 3085 N N   . SER B 2 194 ? 106.548 115.834 144.007 1.00 75.83  ? 189 SER B N   1 
ATOM 3086 C CA  . SER B 2 194 ? 106.988 117.195 143.731 1.00 75.83  ? 189 SER B CA  1 
ATOM 3087 C C   . SER B 2 194 ? 107.463 117.872 145.009 1.00 75.83  ? 189 SER B C   1 
ATOM 3088 O O   . SER B 2 194 ? 106.993 117.578 146.109 1.00 75.83  ? 189 SER B O   1 
ATOM 3089 C CB  . SER B 2 194 ? 105.878 118.008 143.067 1.00 75.83  ? 189 SER B CB  1 
ATOM 3090 O OG  . SER B 2 194 ? 105.798 117.719 141.683 1.00 75.83  ? 189 SER B OG  1 
ATOM 3091 N N   . LEU B 2 195 ? 108.404 118.803 144.838 1.00 71.99  ? 190 LEU B N   1 
ATOM 3092 C CA  . LEU B 2 195 ? 108.975 119.591 145.922 1.00 71.99  ? 190 LEU B CA  1 
ATOM 3093 C C   . LEU B 2 195 ? 109.075 121.042 145.486 1.00 71.99  ? 190 LEU B C   1 
ATOM 3094 O O   . LEU B 2 195 ? 109.127 121.334 144.288 1.00 71.99  ? 190 LEU B O   1 
ATOM 3095 C CB  . LEU B 2 195 ? 110.373 119.113 146.325 1.00 71.99  ? 190 LEU B CB  1 
ATOM 3096 C CG  . LEU B 2 195 ? 110.587 117.950 147.283 1.00 71.99  ? 190 LEU B CG  1 
ATOM 3097 C CD1 . LEU B 2 195 ? 110.032 118.299 148.642 1.00 71.99  ? 190 LEU B CD1 1 
ATOM 3098 C CD2 . LEU B 2 195 ? 109.962 116.694 146.771 1.00 71.99  ? 190 LEU B CD2 1 
ATOM 3099 N N   . SER B 2 196 ? 109.107 121.947 146.464 1.00 70.97  ? 191 SER B N   1 
ATOM 3100 C CA  . SER B 2 196 ? 109.382 123.356 146.194 1.00 70.97  ? 191 SER B CA  1 
ATOM 3101 C C   . SER B 2 196 ? 109.890 123.967 147.498 1.00 70.97  ? 191 SER B C   1 
ATOM 3102 O O   . SER B 2 196 ? 109.140 124.046 148.472 1.00 70.97  ? 191 SER B O   1 
ATOM 3103 C CB  . SER B 2 196 ? 108.150 124.078 145.679 1.00 70.97  ? 191 SER B CB  1 
ATOM 3104 O OG  . SER B 2 196 ? 107.145 124.143 146.672 1.00 70.97  ? 191 SER B OG  1 
ATOM 3105 N N   . LEU B 2 197 ? 111.167 124.336 147.526 1.00 70.66  ? 192 LEU B N   1 
ATOM 3106 C CA  . LEU B 2 197 ? 111.712 125.007 148.696 1.00 70.66  ? 192 LEU B CA  1 
ATOM 3107 C C   . LEU B 2 197 ? 111.209 126.442 148.768 1.00 70.66  ? 192 LEU B C   1 
ATOM 3108 O O   . LEU B 2 197 ? 111.013 127.109 147.751 1.00 70.66  ? 192 LEU B O   1 
ATOM 3109 C CB  . LEU B 2 197 ? 113.235 124.993 148.666 1.00 70.66  ? 192 LEU B CB  1 
ATOM 3110 C CG  . LEU B 2 197 ? 113.904 123.624 148.674 1.00 70.66  ? 192 LEU B CG  1 
ATOM 3111 C CD1 . LEU B 2 197 ? 115.369 123.758 148.313 1.00 70.66  ? 192 LEU B CD1 1 
ATOM 3112 C CD2 . LEU B 2 197 ? 113.743 122.968 150.029 1.00 70.66  ? 192 LEU B CD2 1 
ATOM 3113 N N   . ALA B 2 198 ? 111.000 126.917 149.992 1.00 78.44  ? 193 ALA B N   1 
ATOM 3114 C CA  . ALA B 2 198 ? 110.595 128.294 150.200 1.00 78.44  ? 193 ALA B CA  1 
ATOM 3115 C C   . ALA B 2 198 ? 111.735 129.242 149.837 1.00 78.44  ? 193 ALA B C   1 
ATOM 3116 O O   . ALA B 2 198 ? 112.908 128.864 149.880 1.00 78.44  ? 193 ALA B O   1 
ATOM 3117 C CB  . ALA B 2 198 ? 110.168 128.511 151.649 1.00 78.44  ? 193 ALA B CB  1 
ATOM 3118 N N   . PRO B 2 199 ? 111.410 130.482 149.463 1.00 80.05  ? 194 PRO B N   1 
ATOM 3119 C CA  . PRO B 2 199 ? 112.472 131.443 149.129 1.00 80.05  ? 194 PRO B CA  1 
ATOM 3120 C C   . PRO B 2 199 ? 113.452 131.690 150.260 1.00 80.05  ? 194 PRO B C   1 
ATOM 3121 O O   . PRO B 2 199 ? 114.629 131.963 149.995 1.00 80.05  ? 194 PRO B O   1 
ATOM 3122 C CB  . PRO B 2 199 ? 111.685 132.710 148.776 1.00 80.05  ? 194 PRO B CB  1 
ATOM 3123 C CG  . PRO B 2 199 ? 110.386 132.199 148.279 1.00 80.05  ? 194 PRO B CG  1 
ATOM 3124 C CD  . PRO B 2 199 ? 110.075 131.009 149.137 1.00 80.05  ? 194 PRO B CD  1 
ATOM 3125 N N   . ASP B 2 200 ? 113.013 131.603 151.512 1.00 81.65  ? 195 ASP B N   1 
ATOM 3126 C CA  . ASP B 2 200 ? 113.893 131.821 152.651 1.00 81.65  ? 195 ASP B CA  1 
ATOM 3127 C C   . ASP B 2 200 ? 114.543 130.541 153.161 1.00 81.65  ? 195 ASP B C   1 
ATOM 3128 O O   . ASP B 2 200 ? 115.272 130.590 154.156 1.00 81.65  ? 195 ASP B O   1 
ATOM 3129 C CB  . ASP B 2 200 ? 113.123 132.533 153.776 1.00 81.65  ? 195 ASP B CB  1 
ATOM 3130 C CG  . ASP B 2 200 ? 112.055 131.661 154.415 1.00 81.65  ? 195 ASP B CG  1 
ATOM 3131 O OD1 . ASP B 2 200 ? 112.377 130.583 154.954 1.00 81.65  ? 195 ASP B OD1 1 
ATOM 3132 O OD2 . ASP B 2 200 ? 110.877 132.077 154.401 1.00 81.65  ? 195 ASP B OD2 1 
ATOM 3133 N N   . THR B 2 201 ? 114.297 129.407 152.503 1.00 80.23  ? 196 THR B N   1 
ATOM 3134 C CA  . THR B 2 201 ? 114.974 128.136 152.789 1.00 80.23  ? 196 THR B CA  1 
ATOM 3135 C C   . THR B 2 201 ? 114.806 127.701 154.243 1.00 80.23  ? 196 THR B C   1 
ATOM 3136 O O   . THR B 2 201 ? 115.762 127.278 154.894 1.00 80.23  ? 196 THR B O   1 
ATOM 3137 C CB  . THR B 2 201 ? 116.456 128.195 152.416 1.00 80.23  ? 196 THR B CB  1 
ATOM 3138 O OG1 . THR B 2 201 ? 117.111 129.223 153.169 1.00 80.23  ? 196 THR B OG1 1 
ATOM 3139 C CG2 . THR B 2 201 ? 116.618 128.479 150.932 1.00 80.23  ? 196 THR B CG2 1 
ATOM 3140 N N   . ARG B 2 202 ? 113.581 127.801 154.759 1.00 78.30  ? 197 ARG B N   1 
ATOM 3141 C CA  . ARG B 2 202 ? 113.253 127.256 156.072 1.00 78.30  ? 197 ARG B CA  1 
ATOM 3142 C C   . ARG B 2 202 ? 112.021 126.365 156.083 1.00 78.30  ? 197 ARG B C   1 
ATOM 3143 O O   . ARG B 2 202 ? 111.847 125.608 157.044 1.00 78.30  ? 197 ARG B O   1 
ATOM 3144 C CB  . ARG B 2 202 ? 113.052 128.385 157.092 1.00 78.30  ? 197 ARG B CB  1 
ATOM 3145 N N   . LEU B 2 203 ? 111.166 126.429 155.067 1.00 77.35  ? 198 LEU B N   1 
ATOM 3146 C CA  . LEU B 2 203 ? 109.995 125.576 154.947 1.00 77.35  ? 198 LEU B CA  1 
ATOM 3147 C C   . LEU B 2 203 ? 109.985 124.961 153.553 1.00 77.35  ? 198 LEU B C   1 
ATOM 3148 O O   . LEU B 2 203 ? 110.570 125.505 152.614 1.00 77.35  ? 198 LEU B O   1 
ATOM 3149 C CB  . LEU B 2 203 ? 108.698 126.361 155.184 1.00 77.35  ? 198 LEU B CB  1 
ATOM 3150 C CG  . LEU B 2 203 ? 108.156 126.544 156.604 1.00 77.35  ? 198 LEU B CG  1 
ATOM 3151 C CD1 . LEU B 2 203 ? 109.103 127.345 157.472 1.00 77.35  ? 198 LEU B CD1 1 
ATOM 3152 C CD2 . LEU B 2 203 ? 106.807 127.229 156.551 1.00 77.35  ? 198 LEU B CD2 1 
ATOM 3153 N N   . PHE B 2 204 ? 109.319 123.817 153.416 1.00 75.23  ? 199 PHE B N   1 
ATOM 3154 C CA  . PHE B 2 204 ? 109.190 123.194 152.106 1.00 75.23  ? 199 PHE B CA  1 
ATOM 3155 C C   . PHE B 2 204 ? 107.938 122.332 152.045 1.00 75.23  ? 199 PHE B C   1 
ATOM 3156 O O   . PHE B 2 204 ? 107.619 121.616 152.999 1.00 75.23  ? 199 PHE B O   1 
ATOM 3157 C CB  . PHE B 2 204 ? 110.449 122.392 151.752 1.00 75.23  ? 199 PHE B CB  1 
ATOM 3158 C CG  . PHE B 2 204 ? 110.528 121.038 152.387 1.00 75.23  ? 199 PHE B CG  1 
ATOM 3159 C CD1 . PHE B 2 204 ? 110.665 120.900 153.753 1.00 75.23  ? 199 PHE B CD1 1 
ATOM 3160 C CD2 . PHE B 2 204 ? 110.508 119.901 151.608 1.00 75.23  ? 199 PHE B CD2 1 
ATOM 3161 C CE1 . PHE B 2 204 ? 110.758 119.650 154.324 1.00 75.23  ? 199 PHE B CE1 1 
ATOM 3162 C CE2 . PHE B 2 204 ? 110.598 118.656 152.169 1.00 75.23  ? 199 PHE B CE2 1 
ATOM 3163 C CZ  . PHE B 2 204 ? 110.721 118.527 153.530 1.00 75.23  ? 199 PHE B CZ  1 
ATOM 3164 N N   . VAL B 2 205 ? 107.232 122.417 150.916 1.00 73.80  ? 200 VAL B N   1 
ATOM 3165 C CA  . VAL B 2 205 ? 105.938 121.774 150.719 1.00 73.80  ? 200 VAL B CA  1 
ATOM 3166 C C   . VAL B 2 205 ? 106.054 120.734 149.614 1.00 73.80  ? 200 VAL B C   1 
ATOM 3167 O O   . VAL B 2 205 ? 106.854 120.888 148.687 1.00 73.80  ? 200 VAL B O   1 
ATOM 3168 C CB  . VAL B 2 205 ? 104.839 122.798 150.375 1.00 73.80  ? 200 VAL B CB  1 
ATOM 3169 C CG1 . VAL B 2 205 ? 104.554 123.682 151.568 1.00 73.80  ? 200 VAL B CG1 1 
ATOM 3170 C CG2 . VAL B 2 205 ? 105.244 123.631 149.176 1.00 73.80  ? 200 VAL B CG2 1 
ATOM 3171 N N   . SER B 2 206 ? 105.251 119.677 149.716 1.00 77.12  ? 201 SER B N   1 
ATOM 3172 C CA  . SER B 2 206 ? 105.277 118.575 148.766 1.00 77.12  ? 201 SER B CA  1 
ATOM 3173 C C   . SER B 2 206 ? 103.871 118.032 148.551 1.00 77.12  ? 201 SER B C   1 
ATOM 3174 O O   . SER B 2 206 ? 102.987 118.196 149.395 1.00 77.12  ? 201 SER B O   1 
ATOM 3175 C CB  . SER B 2 206 ? 106.187 117.447 149.244 1.00 77.12  ? 201 SER B CB  1 
ATOM 3176 O OG  . SER B 2 206 ? 105.589 116.735 150.310 1.00 77.12  ? 201 SER B OG  1 
ATOM 3177 N N   . GLY B 2 207 ? 103.678 117.382 147.415 1.00 78.76  ? 202 GLY B N   1 
ATOM 3178 C CA  . GLY B 2 207 ? 102.390 116.796 147.078 1.00 78.76  ? 202 GLY B CA  1 
ATOM 3179 C C   . GLY B 2 207 ? 102.554 115.377 146.586 1.00 78.76  ? 202 GLY B C   1 
ATOM 3180 O O   . GLY B 2 207 ? 103.543 115.045 145.933 1.00 78.76  ? 202 GLY B O   1 
ATOM 3181 N N   . ALA B 2 208 ? 101.570 114.542 146.898 1.00 80.60  ? 203 ALA B N   1 
ATOM 3182 C CA  . ALA B 2 208 ? 101.669 113.105 146.678 1.00 80.60  ? 203 ALA B CA  1 
ATOM 3183 C C   . ALA B 2 208 ? 100.476 112.600 145.868 1.00 80.60  ? 203 ALA B C   1 
ATOM 3184 O O   . ALA B 2 208 ? 99.673  113.378 145.345 1.00 80.60  ? 203 ALA B O   1 
ATOM 3185 C CB  . ALA B 2 208 ? 101.785 112.371 148.013 1.00 80.60  ? 203 ALA B CB  1 
ATOM 3186 N N   . CYS B 2 209 ? 100.370 111.276 145.768 1.00 84.21  ? 204 CYS B N   1 
ATOM 3187 C CA  . CYS B 2 209 ? 99.353  110.619 144.960 1.00 84.21  ? 204 CYS B CA  1 
ATOM 3188 C C   . CYS B 2 209 ? 98.110  110.231 145.748 1.00 84.21  ? 204 CYS B C   1 
ATOM 3189 O O   . CYS B 2 209 ? 97.375  109.341 145.313 1.00 84.21  ? 204 CYS B O   1 
ATOM 3190 C CB  . CYS B 2 209 ? 99.934  109.371 144.290 1.00 84.21  ? 204 CYS B CB  1 
ATOM 3191 S SG  . CYS B 2 209 ? 101.229 109.705 143.077 1.00 84.21  ? 204 CYS B SG  1 
ATOM 3192 N N   . ASP B 2 210 ? 97.861  110.863 146.892 1.00 83.59  ? 205 ASP B N   1 
ATOM 3193 C CA  . ASP B 2 210 ? 96.655  110.619 147.672 1.00 83.59  ? 205 ASP B CA  1 
ATOM 3194 C C   . ASP B 2 210 ? 95.794  111.868 147.833 1.00 83.59  ? 205 ASP B C   1 
ATOM 3195 O O   . ASP B 2 210 ? 95.012  111.960 148.783 1.00 83.59  ? 205 ASP B O   1 
ATOM 3196 C CB  . ASP B 2 210 ? 97.024  109.997 149.023 1.00 83.59  ? 205 ASP B CB  1 
ATOM 3197 C CG  . ASP B 2 210 ? 97.670  110.982 149.997 1.00 83.59  ? 205 ASP B CG  1 
ATOM 3198 O OD1 . ASP B 2 210 ? 97.642  112.208 149.780 1.00 83.59  ? 205 ASP B OD1 1 
ATOM 3199 O OD2 . ASP B 2 210 ? 98.221  110.508 151.013 1.00 83.59  ? 205 ASP B OD2 1 
ATOM 3200 N N   . ALA B 2 211 ? 95.926  112.826 146.914 1.00 83.62  ? 206 ALA B N   1 
ATOM 3201 C CA  . ALA B 2 211 ? 95.137  114.060 146.915 1.00 83.62  ? 206 ALA B CA  1 
ATOM 3202 C C   . ALA B 2 211 ? 95.330  114.858 148.203 1.00 83.62  ? 206 ALA B C   1 
ATOM 3203 O O   . ALA B 2 211 ? 94.385  115.430 148.747 1.00 83.62  ? 206 ALA B O   1 
ATOM 3204 C CB  . ALA B 2 211 ? 93.654  113.770 146.674 1.00 83.62  ? 206 ALA B CB  1 
ATOM 3205 N N   . SER B 2 212 ? 96.565  114.902 148.693 1.00 82.01  ? 207 SER B N   1 
ATOM 3206 C CA  . SER B 2 212 ? 96.906  115.722 149.844 1.00 82.01  ? 207 SER B CA  1 
ATOM 3207 C C   . SER B 2 212 ? 98.264  116.369 149.622 1.00 82.01  ? 207 SER B C   1 
ATOM 3208 O O   . SER B 2 212 ? 99.158  115.777 149.013 1.00 82.01  ? 207 SER B O   1 
ATOM 3209 C CB  . SER B 2 212 ? 96.921  114.906 151.140 1.00 82.01  ? 207 SER B CB  1 
ATOM 3210 O OG  . SER B 2 212 ? 98.078  114.092 151.212 1.00 82.01  ? 207 SER B OG  1 
ATOM 3211 N N   . ALA B 2 213 ? 98.407  117.590 150.123 1.00 80.54  ? 208 ALA B N   1 
ATOM 3212 C CA  . ALA B 2 213 ? 99.665  118.320 150.074 1.00 80.54  ? 208 ALA B CA  1 
ATOM 3213 C C   . ALA B 2 213 ? 100.029 118.757 151.480 1.00 80.54  ? 208 ALA B C   1 
ATOM 3214 O O   . ALA B 2 213 ? 99.164  119.198 152.243 1.00 80.54  ? 208 ALA B O   1 
ATOM 3215 C CB  . ALA B 2 213 ? 99.574  119.535 149.148 1.00 80.54  ? 208 ALA B CB  1 
ATOM 3216 N N   . LYS B 2 214 ? 101.306 118.640 151.824 1.00 80.23  ? 209 LYS B N   1 
ATOM 3217 C CA  . LYS B 2 214 ? 101.754 118.878 153.185 1.00 80.23  ? 209 LYS B CA  1 
ATOM 3218 C C   . LYS B 2 214 ? 102.881 119.901 153.219 1.00 80.23  ? 209 LYS B C   1 
ATOM 3219 O O   . LYS B 2 214 ? 103.617 120.087 152.246 1.00 80.23  ? 209 LYS B O   1 
ATOM 3220 C CB  . LYS B 2 214 ? 102.214 117.574 153.843 1.00 80.23  ? 209 LYS B CB  1 
ATOM 3221 C CG  . LYS B 2 214 ? 101.077 116.665 154.266 1.00 80.23  ? 209 LYS B CG  1 
ATOM 3222 C CD  . LYS B 2 214 ? 101.429 115.900 155.524 1.00 80.23  ? 209 LYS B CD  1 
ATOM 3223 C CE  . LYS B 2 214 ? 100.552 114.679 155.695 1.00 80.23  ? 209 LYS B CE  1 
ATOM 3224 N NZ  . LYS B 2 214 ? 99.122  115.049 155.838 1.00 80.23  ? 209 LYS B NZ  1 
ATOM 3225 N N   . LEU B 2 215 ? 103.003 120.562 154.366 1.00 80.84  ? 210 LEU B N   1 
ATOM 3226 C CA  . LEU B 2 215 ? 104.070 121.515 154.648 1.00 80.84  ? 210 LEU B CA  1 
ATOM 3227 C C   . LEU B 2 215 ? 104.898 120.977 155.804 1.00 80.84  ? 210 LEU B C   1 
ATOM 3228 O O   . LEU B 2 215 ? 104.350 120.366 156.728 1.00 80.84  ? 210 LEU B O   1 
ATOM 3229 C CB  . LEU B 2 215 ? 103.495 122.893 154.980 1.00 80.84  ? 210 LEU B CB  1 
ATOM 3230 C CG  . LEU B 2 215 ? 104.449 124.075 155.141 1.00 80.84  ? 210 LEU B CG  1 
ATOM 3231 C CD1 . LEU B 2 215 ? 103.731 125.347 154.811 1.00 80.84  ? 210 LEU B CD1 1 
ATOM 3232 C CD2 . LEU B 2 215 ? 104.982 124.154 156.565 1.00 80.84  ? 210 LEU B CD2 1 
ATOM 3233 N N   . TRP B 2 216 ? 106.205 121.202 155.755 1.00 80.50  ? 211 TRP B N   1 
ATOM 3234 C CA  . TRP B 2 216 ? 107.113 120.708 156.777 1.00 80.50  ? 211 TRP B CA  1 
ATOM 3235 C C   . TRP B 2 216 ? 108.023 121.821 157.280 1.00 80.50  ? 211 TRP B C   1 
ATOM 3236 O O   . TRP B 2 216 ? 108.253 122.826 156.602 1.00 80.50  ? 211 TRP B O   1 
ATOM 3237 C CB  . TRP B 2 216 ? 107.969 119.558 156.244 1.00 80.50  ? 211 TRP B CB  1 
ATOM 3238 C CG  . TRP B 2 216 ? 107.214 118.497 155.523 1.00 80.50  ? 211 TRP B CG  1 
ATOM 3239 C CD1 . TRP B 2 216 ? 106.652 118.592 154.292 1.00 80.50  ? 211 TRP B CD1 1 
ATOM 3240 C CD2 . TRP B 2 216 ? 106.946 117.170 155.987 1.00 80.50  ? 211 TRP B CD2 1 
ATOM 3241 N NE1 . TRP B 2 216 ? 106.045 117.409 153.956 1.00 80.50  ? 211 TRP B NE1 1 
ATOM 3242 C CE2 . TRP B 2 216 ? 106.211 116.519 154.983 1.00 80.50  ? 211 TRP B CE2 1 
ATOM 3243 C CE3 . TRP B 2 216 ? 107.252 116.470 157.156 1.00 80.50  ? 211 TRP B CE3 1 
ATOM 3244 C CZ2 . TRP B 2 216 ? 105.779 115.205 155.109 1.00 80.50  ? 211 TRP B CZ2 1 
ATOM 3245 C CZ3 . TRP B 2 216 ? 106.821 115.167 157.280 1.00 80.50  ? 211 TRP B CZ3 1 
ATOM 3246 C CH2 . TRP B 2 216 ? 106.097 114.546 156.261 1.00 80.50  ? 211 TRP B CH2 1 
ATOM 3247 N N   . ASP B 2 217 ? 108.539 121.626 158.490 1.00 85.19  ? 212 ASP B N   1 
ATOM 3248 C CA  . ASP B 2 217 ? 109.558 122.488 159.076 1.00 85.19  ? 212 ASP B CA  1 
ATOM 3249 C C   . ASP B 2 217 ? 110.876 121.728 159.055 1.00 85.19  ? 212 ASP B C   1 
ATOM 3250 O O   . ASP B 2 217 ? 110.995 120.674 159.690 1.00 85.19  ? 212 ASP B O   1 
ATOM 3251 C CB  . ASP B 2 217 ? 109.183 122.895 160.499 1.00 85.19  ? 212 ASP B CB  1 
ATOM 3252 C CG  . ASP B 2 217 ? 110.108 123.955 161.069 1.00 85.19  ? 212 ASP B CG  1 
ATOM 3253 O OD1 . ASP B 2 217 ? 111.064 124.358 160.373 1.00 85.19  ? 212 ASP B OD1 1 
ATOM 3254 O OD2 . ASP B 2 217 ? 109.877 124.389 162.218 1.00 85.19  ? 212 ASP B OD2 1 
ATOM 3255 N N   . VAL B 2 218 ? 111.858 122.260 158.327 1.00 83.88  ? 213 VAL B N   1 
ATOM 3256 C CA  . VAL B 2 218 ? 113.067 121.497 158.043 1.00 83.88  ? 213 VAL B CA  1 
ATOM 3257 C C   . VAL B 2 218 ? 113.899 121.299 159.306 1.00 83.88  ? 213 VAL B C   1 
ATOM 3258 O O   . VAL B 2 218 ? 114.512 120.242 159.498 1.00 83.88  ? 213 VAL B O   1 
ATOM 3259 C CB  . VAL B 2 218 ? 113.871 122.177 156.916 1.00 83.88  ? 213 VAL B CB  1 
ATOM 3260 C CG1 . VAL B 2 218 ? 114.323 123.568 157.325 1.00 83.88  ? 213 VAL B CG1 1 
ATOM 3261 C CG2 . VAL B 2 218 ? 115.058 121.321 156.516 1.00 83.88  ? 213 VAL B CG2 1 
ATOM 3262 N N   . ARG B 2 219 ? 113.932 122.300 160.186 1.00 85.65  ? 214 ARG B N   1 
ATOM 3263 C CA  . ARG B 2 219 ? 114.777 122.205 161.373 1.00 85.65  ? 214 ARG B CA  1 
ATOM 3264 C C   . ARG B 2 219 ? 114.181 121.254 162.405 1.00 85.65  ? 214 ARG B C   1 
ATOM 3265 O O   . ARG B 2 219 ? 114.903 120.466 163.026 1.00 85.65  ? 214 ARG B O   1 
ATOM 3266 C CB  . ARG B 2 219 ? 114.991 123.593 161.975 1.00 85.65  ? 214 ARG B CB  1 
ATOM 3267 N N   . GLU B 2 220 ? 112.862 121.308 162.601 1.00 87.03  ? 215 GLU B N   1 
ATOM 3268 C CA  . GLU B 2 220 ? 112.246 120.495 163.645 1.00 87.03  ? 215 GLU B CA  1 
ATOM 3269 C C   . GLU B 2 220 ? 112.006 119.067 163.168 1.00 87.03  ? 215 GLU B C   1 
ATOM 3270 O O   . GLU B 2 220 ? 112.582 118.117 163.710 1.00 87.03  ? 215 GLU B O   1 
ATOM 3271 C CB  . GLU B 2 220 ? 110.938 121.137 164.105 1.00 87.03  ? 215 GLU B CB  1 
ATOM 3272 N N   . GLY B 2 221 ? 111.164 118.895 162.155 1.00 89.03  ? 216 GLY B N   1 
ATOM 3273 C CA  . GLY B 2 221 ? 110.891 117.584 161.608 1.00 89.03  ? 216 GLY B CA  1 
ATOM 3274 C C   . GLY B 2 221 ? 109.468 117.090 161.746 1.00 89.03  ? 216 GLY B C   1 
ATOM 3275 O O   . GLY B 2 221 ? 109.259 115.873 161.763 1.00 89.03  ? 216 GLY B O   1 
ATOM 3276 N N   . MET B 2 222 ? 108.488 117.984 161.842 1.00 91.36  ? 217 MET B N   1 
ATOM 3277 C CA  . MET B 2 222 ? 107.097 117.604 162.039 1.00 91.36  ? 217 MET B CA  1 
ATOM 3278 C C   . MET B 2 222 ? 106.198 118.349 161.063 1.00 91.36  ? 217 MET B C   1 
ATOM 3279 O O   . MET B 2 222 ? 106.472 119.499 160.706 1.00 91.36  ? 217 MET B O   1 
ATOM 3280 C CB  . MET B 2 222 ? 106.647 117.892 163.475 1.00 91.36  ? 217 MET B CB  1 
ATOM 3281 N N   . CYS B 2 223 ? 105.128 117.685 160.634 1.00 92.15  ? 218 CYS B N   1 
ATOM 3282 C CA  . CYS B 2 223 ? 104.120 118.333 159.808 1.00 92.15  ? 218 CYS B CA  1 
ATOM 3283 C C   . CYS B 2 223 ? 103.408 119.417 160.602 1.00 92.15  ? 218 CYS B C   1 
ATOM 3284 O O   . CYS B 2 223 ? 103.300 119.341 161.830 1.00 92.15  ? 218 CYS B O   1 
ATOM 3285 C CB  . CYS B 2 223 ? 103.099 117.315 159.312 1.00 92.15  ? 218 CYS B CB  1 
ATOM 3286 S SG  . CYS B 2 223 ? 103.739 116.094 158.168 1.00 92.15  ? 218 CYS B SG  1 
ATOM 3287 N N   . ARG B 2 224 ? 102.916 120.433 159.899 1.00 94.96  ? 219 ARG B N   1 
ATOM 3288 C CA  . ARG B 2 224 ? 102.176 121.508 160.543 1.00 94.96  ? 219 ARG B CA  1 
ATOM 3289 C C   . ARG B 2 224 ? 100.760 121.646 160.011 1.00 94.96  ? 219 ARG B C   1 
ATOM 3290 O O   . ARG B 2 224 ? 99.821  121.813 160.799 1.00 94.96  ? 219 ARG B O   1 
ATOM 3291 C CB  . ARG B 2 224 ? 102.928 122.836 160.389 1.00 94.96  ? 219 ARG B CB  1 
ATOM 3292 C CG  . ARG B 2 224 ? 104.232 122.886 161.155 1.00 94.96  ? 219 ARG B CG  1 
ATOM 3293 C CD  . ARG B 2 224 ? 104.864 124.259 161.085 1.00 94.96  ? 219 ARG B CD  1 
ATOM 3294 N NE  . ARG B 2 224 ? 106.198 124.269 161.674 1.00 94.96  ? 219 ARG B NE  1 
ATOM 3295 C CZ  . ARG B 2 224 ? 106.441 124.453 162.967 1.00 94.96  ? 219 ARG B CZ  1 
ATOM 3296 N NH1 . ARG B 2 224 ? 105.437 124.642 163.811 1.00 94.96  ? 219 ARG B NH1 1 
ATOM 3297 N NH2 . ARG B 2 224 ? 107.687 124.446 163.416 1.00 94.96  ? 219 ARG B NH2 1 
ATOM 3298 N N   . GLN B 2 225 ? 100.571 121.586 158.695 1.00 94.23  ? 220 GLN B N   1 
ATOM 3299 C CA  . GLN B 2 225 ? 99.251  121.708 158.097 1.00 94.23  ? 220 GLN B CA  1 
ATOM 3300 C C   . GLN B 2 225 ? 99.076  120.656 157.013 1.00 94.23  ? 220 GLN B C   1 
ATOM 3301 O O   . GLN B 2 225 ? 100.044 120.184 156.412 1.00 94.23  ? 220 GLN B O   1 
ATOM 3302 C CB  . GLN B 2 225 ? 99.025  123.109 157.512 1.00 94.23  ? 220 GLN B CB  1 
ATOM 3303 C CG  . GLN B 2 225 ? 99.551  124.239 158.379 1.00 94.23  ? 220 GLN B CG  1 
ATOM 3304 C CD  . GLN B 2 225 ? 99.398  125.597 157.732 1.00 94.23  ? 220 GLN B CD  1 
ATOM 3305 O OE1 . GLN B 2 225 ? 98.467  125.829 156.964 1.00 94.23  ? 220 GLN B OE1 1 
ATOM 3306 N NE2 . GLN B 2 225 ? 100.313 126.507 158.042 1.00 94.23  ? 220 GLN B NE2 1 
ATOM 3307 N N   . THR B 2 226 ? 97.818  120.289 156.771 1.00 93.97  ? 221 THR B N   1 
ATOM 3308 C CA  . THR B 2 226 ? 97.466  119.342 155.722 1.00 93.97  ? 221 THR B CA  1 
ATOM 3309 C C   . THR B 2 226 ? 96.297  119.890 154.920 1.00 93.97  ? 221 THR B C   1 
ATOM 3310 O O   . THR B 2 226 ? 95.253  120.219 155.489 1.00 93.97  ? 221 THR B O   1 
ATOM 3311 C CB  . THR B 2 226 ? 97.101  117.973 156.301 1.00 93.97  ? 221 THR B CB  1 
ATOM 3312 O OG1 . THR B 2 226 ? 98.243  117.410 156.957 1.00 93.97  ? 221 THR B OG1 1 
ATOM 3313 C CG2 . THR B 2 226 ? 96.630  117.038 155.200 1.00 93.97  ? 221 THR B CG2 1 
ATOM 3314 N N   . PHE B 2 227 ? 96.471  119.974 153.605 1.00 92.63  ? 222 PHE B N   1 
ATOM 3315 C CA  . PHE B 2 227 ? 95.456  120.497 152.703 1.00 92.63  ? 222 PHE B CA  1 
ATOM 3316 C C   . PHE B 2 227 ? 94.967  119.374 151.803 1.00 92.63  ? 222 PHE B C   1 
ATOM 3317 O O   . PHE B 2 227 ? 95.777  118.601 151.279 1.00 92.63  ? 222 PHE B O   1 
ATOM 3318 C CB  . PHE B 2 227 ? 96.009  121.643 151.852 1.00 92.63  ? 222 PHE B CB  1 
ATOM 3319 C CG  . PHE B 2 227 ? 96.555  122.790 152.652 1.00 92.63  ? 222 PHE B CG  1 
ATOM 3320 C CD1 . PHE B 2 227 ? 97.881  122.811 153.035 1.00 92.63  ? 222 PHE B CD1 1 
ATOM 3321 C CD2 . PHE B 2 227 ? 95.746  123.853 153.005 1.00 92.63  ? 222 PHE B CD2 1 
ATOM 3322 C CE1 . PHE B 2 227 ? 98.390  123.862 153.761 1.00 92.63  ? 222 PHE B CE1 1 
ATOM 3323 C CE2 . PHE B 2 227 ? 96.252  124.911 153.732 1.00 92.63  ? 222 PHE B CE2 1 
ATOM 3324 C CZ  . PHE B 2 227 ? 97.577  124.912 154.110 1.00 92.63  ? 222 PHE B CZ  1 
ATOM 3325 N N   . THR B 2 228 ? 93.658  119.255 151.600 1.00 91.16  ? 223 THR B N   1 
ATOM 3326 C CA  . THR B 2 228 ? 93.150  118.158 150.768 1.00 91.16  ? 223 THR B CA  1 
ATOM 3327 C C   . THR B 2 228 ? 92.124  118.533 149.693 1.00 91.16  ? 223 THR B C   1 
ATOM 3328 O O   . THR B 2 228 ? 91.096  117.872 149.557 1.00 91.16  ? 223 THR B O   1 
ATOM 3329 C CB  . THR B 2 228 ? 92.553  117.034 151.638 1.00 91.16  ? 223 THR B CB  1 
ATOM 3330 O OG1 . THR B 2 228 ? 92.076  115.976 150.796 1.00 91.16  ? 223 THR B OG1 1 
ATOM 3331 C CG2 . THR B 2 228 ? 91.401  117.566 152.477 1.00 91.16  ? 223 THR B CG2 1 
ATOM 3332 N N   . GLY B 2 229 ? 92.403  119.588 148.936 1.00 89.53  ? 224 GLY B N   1 
ATOM 3333 C CA  . GLY B 2 229 ? 91.506  120.022 147.877 1.00 89.53  ? 224 GLY B CA  1 
ATOM 3334 C C   . GLY B 2 229 ? 91.313  119.046 146.724 1.00 89.53  ? 224 GLY B C   1 
ATOM 3335 O O   . GLY B 2 229 ? 90.198  118.870 146.231 1.00 89.53  ? 224 GLY B O   1 
ATOM 3336 N N   . HIS B 2 230 ? 92.402  118.415 146.294 1.00 85.05  ? 225 HIS B N   1 
ATOM 3337 C CA  . HIS B 2 230 ? 92.382  117.472 145.169 1.00 85.05  ? 225 HIS B CA  1 
ATOM 3338 C C   . HIS B 2 230 ? 91.684  116.130 145.411 1.00 85.05  ? 225 HIS B C   1 
ATOM 3339 O O   . HIS B 2 230 ? 91.656  115.620 146.531 1.00 85.05  ? 225 HIS B O   1 
ATOM 3340 C CB  . HIS B 2 230 ? 93.803  117.231 144.651 1.00 85.05  ? 225 HIS B CB  1 
ATOM 3341 C CG  . HIS B 2 230 ? 94.315  118.321 143.761 1.00 85.05  ? 225 HIS B CG  1 
ATOM 3342 N ND1 . HIS B 2 230 ? 94.155  118.300 142.393 1.00 85.05  ? 225 HIS B ND1 1 
ATOM 3343 C CD2 . HIS B 2 230 ? 94.983  119.464 144.044 1.00 85.05  ? 225 HIS B CD2 1 
ATOM 3344 C CE1 . HIS B 2 230 ? 94.703  119.383 141.871 1.00 85.05  ? 225 HIS B CE1 1 
ATOM 3345 N NE2 . HIS B 2 230 ? 95.212  120.107 142.852 1.00 85.05  ? 225 HIS B NE2 1 
ATOM 3346 N N   . GLU B 2 231 ? 91.124  115.573 144.339 1.00 84.84  ? 226 GLU B N   1 
ATOM 3347 C CA  . GLU B 2 231 ? 90.437  114.283 144.383 1.00 84.84  ? 226 GLU B CA  1 
ATOM 3348 C C   . GLU B 2 231 ? 91.368  113.183 143.873 1.00 84.84  ? 226 GLU B C   1 
ATOM 3349 O O   . GLU B 2 231 ? 91.515  112.134 144.502 1.00 84.84  ? 226 GLU B O   1 
ATOM 3350 C CB  . GLU B 2 231 ? 89.159  114.323 143.546 1.00 84.84  ? 226 GLU B CB  1 
ATOM 3351 N N   . SER B 2 232 ? 91.996  113.436 142.726 1.00 82.46  ? 227 SER B N   1 
ATOM 3352 C CA  . SER B 2 232 ? 92.945  112.513 142.119 1.00 82.46  ? 227 SER B CA  1 
ATOM 3353 C C   . SER B 2 232 ? 94.348  112.913 142.560 1.00 82.46  ? 227 SER B C   1 
ATOM 3354 O O   . SER B 2 232 ? 94.523  113.683 143.508 1.00 82.46  ? 227 SER B O   1 
ATOM 3355 C CB  . SER B 2 232 ? 92.793  112.504 140.595 1.00 82.46  ? 227 SER B CB  1 
ATOM 3356 O OG  . SER B 2 232 ? 93.656  111.546 140.006 1.00 82.46  ? 227 SER B OG  1 
ATOM 3357 N N   . ASP B 2 233 ? 95.352  112.395 141.864 1.00 81.02  ? 228 ASP B N   1 
ATOM 3358 C CA  . ASP B 2 233 ? 96.735  112.544 142.289 1.00 81.02  ? 228 ASP B CA  1 
ATOM 3359 C C   . ASP B 2 233 ? 97.364  113.845 141.785 1.00 81.02  ? 228 ASP B C   1 
ATOM 3360 O O   . ASP B 2 233 ? 97.039  114.356 140.713 1.00 81.02  ? 228 ASP B O   1 
ATOM 3361 C CB  . ASP B 2 233 ? 97.550  111.324 141.848 1.00 81.02  ? 228 ASP B CB  1 
ATOM 3362 C CG  . ASP B 2 233 ? 97.607  111.153 140.340 1.00 81.02  ? 228 ASP B CG  1 
ATOM 3363 O OD1 . ASP B 2 233 ? 96.985  111.945 139.604 1.00 81.02  ? 228 ASP B OD1 1 
ATOM 3364 O OD2 . ASP B 2 233 ? 98.275  110.203 139.885 1.00 81.02  ? 228 ASP B OD2 1 
ATOM 3365 N N   . ILE B 2 234 ? 98.283  114.378 142.599 1.00 74.58  ? 229 ILE B N   1 
ATOM 3366 C CA  . ILE B 2 234 ? 98.946  115.659 142.369 1.00 74.58  ? 229 ILE B CA  1 
ATOM 3367 C C   . ILE B 2 234 ? 100.224 115.430 141.578 1.00 74.58  ? 229 ILE B C   1 
ATOM 3368 O O   . ILE B 2 234 ? 100.953 114.460 141.822 1.00 74.58  ? 229 ILE B O   1 
ATOM 3369 C CB  . ILE B 2 234 ? 99.240  116.361 143.709 1.00 74.58  ? 229 ILE B CB  1 
ATOM 3370 C CG1 . ILE B 2 234 ? 98.005  117.108 144.198 1.00 74.58  ? 229 ILE B CG1 1 
ATOM 3371 C CG2 . ILE B 2 234 ? 100.419 117.310 143.594 1.00 74.58  ? 229 ILE B CG2 1 
ATOM 3372 C CD1 . ILE B 2 234 ? 98.210  117.815 145.507 1.00 74.58  ? 229 ILE B CD1 1 
ATOM 3373 N N   . ASN B 2 235 ? 100.506 116.323 140.624 1.00 72.93  ? 230 ASN B N   1 
ATOM 3374 C CA  . ASN B 2 235 ? 101.653 116.171 139.744 1.00 72.93  ? 230 ASN B CA  1 
ATOM 3375 C C   . ASN B 2 235 ? 102.653 117.320 139.783 1.00 72.93  ? 230 ASN B C   1 
ATOM 3376 O O   . ASN B 2 235 ? 103.741 117.175 139.216 1.00 72.93  ? 230 ASN B O   1 
ATOM 3377 C CB  . ASN B 2 235 ? 101.187 115.981 138.293 1.00 72.93  ? 230 ASN B CB  1 
ATOM 3378 C CG  . ASN B 2 235 ? 100.712 114.575 138.016 1.00 72.93  ? 230 ASN B CG  1 
ATOM 3379 O OD1 . ASN B 2 235 ? 99.523  114.339 137.815 1.00 72.93  ? 230 ASN B OD1 1 
ATOM 3380 N ND2 . ASN B 2 235 ? 101.642 113.632 137.993 1.00 72.93  ? 230 ASN B ND2 1 
ATOM 3381 N N   . ALA B 2 236 ? 102.335 118.445 140.420 1.00 71.50  ? 231 ALA B N   1 
ATOM 3382 C CA  . ALA B 2 236 ? 103.284 119.550 140.466 1.00 71.50  ? 231 ALA B CA  1 
ATOM 3383 C C   . ALA B 2 236 ? 102.943 120.465 141.630 1.00 71.50  ? 231 ALA B C   1 
ATOM 3384 O O   . ALA B 2 236 ? 101.817 120.466 142.133 1.00 71.50  ? 231 ALA B O   1 
ATOM 3385 C CB  . ALA B 2 236 ? 103.288 120.338 139.153 1.00 71.50  ? 231 ALA B CB  1 
ATOM 3386 N N   . ILE B 2 237 ? 103.933 121.259 142.041 1.00 71.66  ? 232 ILE B N   1 
ATOM 3387 C CA  . ILE B 2 237 ? 103.757 122.210 143.132 1.00 71.66  ? 232 ILE B CA  1 
ATOM 3388 C C   . ILE B 2 237 ? 104.875 123.238 143.036 1.00 71.66  ? 232 ILE B C   1 
ATOM 3389 O O   . ILE B 2 237 ? 105.986 122.926 142.602 1.00 71.66  ? 232 ILE B O   1 
ATOM 3390 C CB  . ILE B 2 237 ? 103.747 121.481 144.500 1.00 71.66  ? 232 ILE B CB  1 
ATOM 3391 C CG1 . ILE B 2 237 ? 103.305 122.414 145.621 1.00 71.66  ? 232 ILE B CG1 1 
ATOM 3392 C CG2 . ILE B 2 237 ? 105.121 120.930 144.831 1.00 71.66  ? 232 ILE B CG2 1 
ATOM 3393 C CD1 . ILE B 2 237 ? 102.976 121.674 146.892 1.00 71.66  ? 232 ILE B CD1 1 
ATOM 3394 N N   . CYS B 2 238 ? 104.571 124.477 143.419 1.00 73.78  ? 233 CYS B N   1 
ATOM 3395 C CA  . CYS B 2 238 ? 105.568 125.540 143.437 1.00 73.78  ? 233 CYS B CA  1 
ATOM 3396 C C   . CYS B 2 238 ? 105.066 126.686 144.303 1.00 73.78  ? 233 CYS B C   1 
ATOM 3397 O O   . CYS B 2 238 ? 103.858 126.925 144.395 1.00 73.78  ? 233 CYS B O   1 
ATOM 3398 C CB  . CYS B 2 238 ? 105.879 126.044 142.027 1.00 73.78  ? 233 CYS B CB  1 
ATOM 3399 S SG  . CYS B 2 238 ? 104.481 126.821 141.194 1.00 73.78  ? 233 CYS B SG  1 
ATOM 3400 N N   . PHE B 2 239 ? 106.001 127.394 144.935 1.00 75.41  ? 234 PHE B N   1 
ATOM 3401 C CA  . PHE B 2 239 ? 105.673 128.568 145.732 1.00 75.41  ? 234 PHE B CA  1 
ATOM 3402 C C   . PHE B 2 239 ? 105.388 129.797 144.886 1.00 75.41  ? 234 PHE B C   1 
ATOM 3403 O O   . PHE B 2 239 ? 106.101 130.095 143.925 1.00 75.41  ? 234 PHE B O   1 
ATOM 3404 C CB  . PHE B 2 239 ? 106.774 128.930 146.732 1.00 75.41  ? 234 PHE B CB  1 
ATOM 3405 C CG  . PHE B 2 239 ? 106.783 128.100 147.980 1.00 75.41  ? 234 PHE B CG  1 
ATOM 3406 C CD1 . PHE B 2 239 ? 105.922 128.418 149.015 1.00 75.41  ? 234 PHE B CD1 1 
ATOM 3407 C CD2 . PHE B 2 239 ? 107.669 127.063 148.156 1.00 75.41  ? 234 PHE B CD2 1 
ATOM 3408 C CE1 . PHE B 2 239 ? 105.920 127.702 150.180 1.00 75.41  ? 234 PHE B CE1 1 
ATOM 3409 C CE2 . PHE B 2 239 ? 107.667 126.343 149.332 1.00 75.41  ? 234 PHE B CE2 1 
ATOM 3410 C CZ  . PHE B 2 239 ? 106.792 126.662 150.340 1.00 75.41  ? 234 PHE B CZ  1 
ATOM 3411 N N   . PHE B 2 240 ? 104.333 130.500 145.271 1.00 80.46  ? 235 PHE B N   1 
ATOM 3412 C CA  . PHE B 2 240 ? 104.158 131.894 144.916 1.00 80.46  ? 235 PHE B CA  1 
ATOM 3413 C C   . PHE B 2 240 ? 105.323 132.684 145.509 1.00 80.46  ? 235 PHE B C   1 
ATOM 3414 O O   . PHE B 2 240 ? 105.817 132.336 146.586 1.00 80.46  ? 235 PHE B O   1 
ATOM 3415 C CB  . PHE B 2 240 ? 102.816 132.367 145.481 1.00 80.46  ? 235 PHE B CB  1 
ATOM 3416 C CG  . PHE B 2 240 ? 102.453 133.782 145.160 1.00 80.46  ? 235 PHE B CG  1 
ATOM 3417 C CD1 . PHE B 2 240 ? 101.999 134.122 143.904 1.00 80.46  ? 235 PHE B CD1 1 
ATOM 3418 C CD2 . PHE B 2 240 ? 102.520 134.764 146.127 1.00 80.46  ? 235 PHE B CD2 1 
ATOM 3419 C CE1 . PHE B 2 240 ? 101.642 135.417 143.612 1.00 80.46  ? 235 PHE B CE1 1 
ATOM 3420 C CE2 . PHE B 2 240 ? 102.168 136.062 145.838 1.00 80.46  ? 235 PHE B CE2 1 
ATOM 3421 C CZ  . PHE B 2 240 ? 101.728 136.389 144.578 1.00 80.46  ? 235 PHE B CZ  1 
ATOM 3422 N N   . PRO B 2 241 ? 105.800 133.730 144.831 1.00 80.89  ? 236 PRO B N   1 
ATOM 3423 C CA  . PRO B 2 241 ? 107.036 134.398 145.286 1.00 80.89  ? 236 PRO B CA  1 
ATOM 3424 C C   . PRO B 2 241 ? 106.988 134.914 146.717 1.00 80.89  ? 236 PRO B C   1 
ATOM 3425 O O   . PRO B 2 241 ? 108.045 135.046 147.347 1.00 80.89  ? 236 PRO B O   1 
ATOM 3426 C CB  . PRO B 2 241 ? 107.210 135.554 144.292 1.00 80.89  ? 236 PRO B CB  1 
ATOM 3427 C CG  . PRO B 2 241 ? 106.141 135.405 143.259 1.00 80.89  ? 236 PRO B CG  1 
ATOM 3428 C CD  . PRO B 2 241 ? 105.408 134.128 143.472 1.00 80.89  ? 236 PRO B CD  1 
ATOM 3429 N N   . ASN B 2 242 ? 105.805 135.221 147.247 1.00 84.86  ? 237 ASN B N   1 
ATOM 3430 C CA  . ASN B 2 242 ? 105.710 135.757 148.601 1.00 84.86  ? 237 ASN B CA  1 
ATOM 3431 C C   . ASN B 2 242 ? 106.275 134.784 149.627 1.00 84.86  ? 237 ASN B C   1 
ATOM 3432 O O   . ASN B 2 242 ? 107.075 135.166 150.488 1.00 84.86  ? 237 ASN B O   1 
ATOM 3433 C CB  . ASN B 2 242 ? 104.254 136.085 148.928 1.00 84.86  ? 237 ASN B CB  1 
ATOM 3434 C CG  . ASN B 2 242 ? 104.096 136.806 150.250 1.00 84.86  ? 237 ASN B CG  1 
ATOM 3435 O OD1 . ASN B 2 242 ? 105.075 137.135 150.918 1.00 84.86  ? 237 ASN B OD1 1 
ATOM 3436 N ND2 . ASN B 2 242 ? 102.851 137.048 150.644 1.00 84.86  ? 237 ASN B ND2 1 
ATOM 3437 N N   . GLY B 2 243 ? 105.877 133.522 149.545 1.00 87.45  ? 238 GLY B N   1 
ATOM 3438 C CA  . GLY B 2 243 ? 106.125 132.572 150.606 1.00 87.45  ? 238 GLY B CA  1 
ATOM 3439 C C   . GLY B 2 243 ? 104.925 132.272 151.474 1.00 87.45  ? 238 GLY B C   1 
ATOM 3440 O O   . GLY B 2 243 ? 105.094 131.713 152.562 1.00 87.45  ? 238 GLY B O   1 
ATOM 3441 N N   . ASN B 2 244 ? 103.718 132.632 151.029 1.00 90.08  ? 239 ASN B N   1 
ATOM 3442 C CA  . ASN B 2 244 ? 102.496 132.401 151.788 1.00 90.08  ? 239 ASN B CA  1 
ATOM 3443 C C   . ASN B 2 244 ? 101.422 131.729 150.942 1.00 90.08  ? 239 ASN B C   1 
ATOM 3444 O O   . ASN B 2 244 ? 100.247 131.744 151.317 1.00 90.08  ? 239 ASN B O   1 
ATOM 3445 C CB  . ASN B 2 244 ? 101.965 133.714 152.362 1.00 90.08  ? 239 ASN B CB  1 
ATOM 3446 C CG  . ASN B 2 244 ? 102.916 134.338 153.359 1.00 90.08  ? 239 ASN B CG  1 
ATOM 3447 O OD1 . ASN B 2 244 ? 103.461 135.417 153.123 1.00 90.08  ? 239 ASN B OD1 1 
ATOM 3448 N ND2 . ASN B 2 244 ? 103.122 133.663 154.483 1.00 90.08  ? 239 ASN B ND2 1 
ATOM 3449 N N   . ALA B 2 245 ? 101.799 131.140 149.810 1.00 83.89  ? 240 ALA B N   1 
ATOM 3450 C CA  . ALA B 2 245 ? 100.845 130.475 148.936 1.00 83.89  ? 240 ALA B CA  1 
ATOM 3451 C C   . ALA B 2 245 ? 101.591 129.487 148.054 1.00 83.89  ? 240 ALA B C   1 
ATOM 3452 O O   . ALA B 2 245 ? 102.801 129.599 147.848 1.00 83.89  ? 240 ALA B O   1 
ATOM 3453 C CB  . ALA B 2 245 ? 100.070 131.481 148.082 1.00 83.89  ? 240 ALA B CB  1 
ATOM 3454 N N   . PHE B 2 246 ? 100.847 128.516 147.535 1.00 80.98  ? 241 PHE B N   1 
ATOM 3455 C CA  . PHE B 2 246 ? 101.405 127.515 146.639 1.00 80.98  ? 241 PHE B CA  1 
ATOM 3456 C C   . PHE B 2 246 ? 100.286 126.949 145.781 1.00 80.98  ? 241 PHE B C   1 
ATOM 3457 O O   . PHE B 2 246 ? 99.144  126.820 146.231 1.00 80.98  ? 241 PHE B O   1 
ATOM 3458 C CB  . PHE B 2 246 ? 102.125 126.405 147.412 1.00 80.98  ? 241 PHE B CB  1 
ATOM 3459 C CG  . PHE B 2 246 ? 101.225 125.567 148.274 1.00 80.98  ? 241 PHE B CG  1 
ATOM 3460 C CD1 . PHE B 2 246 ? 100.605 126.104 149.386 1.00 80.98  ? 241 PHE B CD1 1 
ATOM 3461 C CD2 . PHE B 2 246 ? 101.016 124.235 147.983 1.00 80.98  ? 241 PHE B CD2 1 
ATOM 3462 C CE1 . PHE B 2 246 ? 99.791  125.331 150.180 1.00 80.98  ? 241 PHE B CE1 1 
ATOM 3463 C CE2 . PHE B 2 246 ? 100.203 123.461 148.769 1.00 80.98  ? 241 PHE B CE2 1 
ATOM 3464 C CZ  . PHE B 2 246 ? 99.589  124.008 149.870 1.00 80.98  ? 241 PHE B CZ  1 
ATOM 3465 N N   . ALA B 2 247 ? 100.626 126.611 144.539 1.00 73.31  ? 242 ALA B N   1 
ATOM 3466 C CA  . ALA B 2 247 ? 99.655  126.173 143.550 1.00 73.31  ? 242 ALA B CA  1 
ATOM 3467 C C   . ALA B 2 247 ? 100.012 124.783 143.057 1.00 73.31  ? 242 ALA B C   1 
ATOM 3468 O O   . ALA B 2 247 ? 101.188 124.479 142.833 1.00 73.31  ? 242 ALA B O   1 
ATOM 3469 C CB  . ALA B 2 247 ? 99.590  127.141 142.372 1.00 73.31  ? 242 ALA B CB  1 
ATOM 3470 N N   . THR B 2 248 ? 98.997  123.941 142.883 1.00 75.44  ? 243 THR B N   1 
ATOM 3471 C CA  . THR B 2 248 ? 99.196  122.550 142.509 1.00 75.44  ? 243 THR B CA  1 
ATOM 3472 C C   . THR B 2 248 ? 98.307  122.181 141.332 1.00 75.44  ? 243 THR B C   1 
ATOM 3473 O O   . THR B 2 248 ? 97.210  122.724 141.173 1.00 75.44  ? 243 THR B O   1 
ATOM 3474 C CB  . THR B 2 248 ? 98.906  121.613 143.684 1.00 75.44  ? 243 THR B CB  1 
ATOM 3475 O OG1 . THR B 2 248 ? 99.007  120.253 143.248 1.00 75.44  ? 243 THR B OG1 1 
ATOM 3476 C CG2 . THR B 2 248 ? 97.512  121.863 144.235 1.00 75.44  ? 243 THR B CG2 1 
ATOM 3477 N N   . GLY B 2 249 ? 98.793  121.260 140.508 1.00 76.23  ? 244 GLY B N   1 
ATOM 3478 C CA  . GLY B 2 249 ? 98.041  120.758 139.376 1.00 76.23  ? 244 GLY B CA  1 
ATOM 3479 C C   . GLY B 2 249 ? 97.987  119.244 139.431 1.00 76.23  ? 244 GLY B C   1 
ATOM 3480 O O   . GLY B 2 249 ? 98.880  118.597 139.982 1.00 76.23  ? 244 GLY B O   1 
ATOM 3481 N N   . SER B 2 250 ? 96.931  118.680 138.854 1.00 79.63  ? 245 SER B N   1 
ATOM 3482 C CA  . SER B 2 250 ? 96.630  117.271 139.047 1.00 79.63  ? 245 SER B CA  1 
ATOM 3483 C C   . SER B 2 250 ? 96.088  116.670 137.761 1.00 79.63  ? 245 SER B C   1 
ATOM 3484 O O   . SER B 2 250 ? 95.846  117.368 136.772 1.00 79.63  ? 245 SER B O   1 
ATOM 3485 C CB  . SER B 2 250 ? 95.626  117.072 140.185 1.00 79.63  ? 245 SER B CB  1 
ATOM 3486 O OG  . SER B 2 250 ? 94.465  117.855 139.979 1.00 79.63  ? 245 SER B OG  1 
ATOM 3487 N N   . ASP B 2 251 ? 95.895  115.354 137.788 1.00 81.40  ? 246 ASP B N   1 
ATOM 3488 C CA  . ASP B 2 251 ? 95.326  114.613 136.672 1.00 81.40  ? 246 ASP B CA  1 
ATOM 3489 C C   . ASP B 2 251 ? 93.811  114.729 136.608 1.00 81.40  ? 246 ASP B C   1 
ATOM 3490 O O   . ASP B 2 251 ? 93.172  113.964 135.880 1.00 81.40  ? 246 ASP B O   1 
ATOM 3491 C CB  . ASP B 2 251 ? 95.734  113.142 136.758 1.00 81.40  ? 246 ASP B CB  1 
ATOM 3492 C CG  . ASP B 2 251 ? 95.740  112.461 135.411 1.00 81.40  ? 246 ASP B CG  1 
ATOM 3493 O OD1 . ASP B 2 251 ? 95.459  113.138 134.400 1.00 81.40  ? 246 ASP B OD1 1 
ATOM 3494 O OD2 . ASP B 2 251 ? 96.026  111.247 135.359 1.00 81.40  ? 246 ASP B OD2 1 
ATOM 3495 N N   . ASP B 2 252 ? 93.232  115.659 137.358 1.00 82.42  ? 247 ASP B N   1 
ATOM 3496 C CA  . ASP B 2 252 ? 91.812  115.972 137.298 1.00 82.42  ? 247 ASP B CA  1 
ATOM 3497 C C   . ASP B 2 252 ? 91.511  117.113 136.336 1.00 82.42  ? 247 ASP B C   1 
ATOM 3498 O O   . ASP B 2 252 ? 90.356  117.545 136.252 1.00 82.42  ? 247 ASP B O   1 
ATOM 3499 C CB  . ASP B 2 252 ? 91.299  116.321 138.700 1.00 82.42  ? 247 ASP B CB  1 
ATOM 3500 C CG  . ASP B 2 252 ? 89.789  116.297 138.795 1.00 82.42  ? 247 ASP B CG  1 
ATOM 3501 O OD1 . ASP B 2 252 ? 89.208  115.192 138.785 1.00 82.42  ? 247 ASP B OD1 1 
ATOM 3502 O OD2 . ASP B 2 252 ? 89.180  117.384 138.881 1.00 82.42  ? 247 ASP B OD2 1 
ATOM 3503 N N   . ALA B 2 253 ? 92.524  117.617 135.629 1.00 81.23  ? 248 ALA B N   1 
ATOM 3504 C CA  . ALA B 2 253 ? 92.417  118.724 134.683 1.00 81.23  ? 248 ALA B CA  1 
ATOM 3505 C C   . ALA B 2 253 ? 92.105  120.055 135.355 1.00 81.23  ? 248 ALA B C   1 
ATOM 3506 O O   . ALA B 2 253 ? 91.669  120.995 134.686 1.00 81.23  ? 248 ALA B O   1 
ATOM 3507 C CB  . ALA B 2 253 ? 91.377  118.439 133.592 1.00 81.23  ? 248 ALA B CB  1 
ATOM 3508 N N   . THR B 2 254 ? 92.328  120.172 136.660 1.00 80.83  ? 249 THR B N   1 
ATOM 3509 C CA  . THR B 2 254 ? 92.050  121.402 137.387 1.00 80.83  ? 249 THR B CA  1 
ATOM 3510 C C   . THR B 2 254 ? 93.242  121.788 138.249 1.00 80.83  ? 249 THR B C   1 
ATOM 3511 O O   . THR B 2 254 ? 93.796  120.954 138.968 1.00 80.83  ? 249 THR B O   1 
ATOM 3512 C CB  . THR B 2 254 ? 90.812  121.257 138.276 1.00 80.83  ? 249 THR B CB  1 
ATOM 3513 O OG1 . THR B 2 254 ? 91.035  120.223 139.242 1.00 80.83  ? 249 THR B OG1 1 
ATOM 3514 C CG2 . THR B 2 254 ? 89.584  120.916 137.443 1.00 80.83  ? 249 THR B CG2 1 
ATOM 3515 N N   . CYS B 2 255 ? 93.626  123.057 138.175 1.00 81.23  ? 250 CYS B N   1 
ATOM 3516 C CA  . CYS B 2 255 ? 94.641  123.627 139.048 1.00 81.23  ? 250 CYS B CA  1 
ATOM 3517 C C   . CYS B 2 255 ? 93.974  124.334 140.222 1.00 81.23  ? 250 CYS B C   1 
ATOM 3518 O O   . CYS B 2 255 ? 92.813  124.740 140.155 1.00 81.23  ? 250 CYS B O   1 
ATOM 3519 C CB  . CYS B 2 255 ? 95.530  124.608 138.284 1.00 81.23  ? 250 CYS B CB  1 
ATOM 3520 S SG  . CYS B 2 255 ? 96.714  123.841 137.162 1.00 81.23  ? 250 CYS B SG  1 
ATOM 3521 N N   . ARG B 2 256 ? 94.730  124.481 141.308 1.00 83.15  ? 251 ARG B N   1 
ATOM 3522 C CA  . ARG B 2 256 ? 94.228  125.133 142.508 1.00 83.15  ? 251 ARG B CA  1 
ATOM 3523 C C   . ARG B 2 256 ? 95.340  125.941 143.156 1.00 83.15  ? 251 ARG B C   1 
ATOM 3524 O O   . ARG B 2 256 ? 96.525  125.735 142.885 1.00 83.15  ? 251 ARG B O   1 
ATOM 3525 C CB  . ARG B 2 256 ? 93.655  124.120 143.506 1.00 83.15  ? 251 ARG B CB  1 
ATOM 3526 C CG  . ARG B 2 256 ? 92.357  123.481 143.053 1.00 83.15  ? 251 ARG B CG  1 
ATOM 3527 C CD  . ARG B 2 256 ? 91.966  122.308 143.928 1.00 83.15  ? 251 ARG B CD  1 
ATOM 3528 N NE  . ARG B 2 256 ? 90.523  122.096 143.908 1.00 83.15  ? 251 ARG B NE  1 
ATOM 3529 C CZ  . ARG B 2 256 ? 89.917  121.169 143.178 1.00 83.15  ? 251 ARG B CZ  1 
ATOM 3530 N NH1 . ARG B 2 256 ? 90.628  120.364 142.405 1.00 83.15  ? 251 ARG B NH1 1 
ATOM 3531 N NH2 . ARG B 2 256 ? 88.599  121.049 143.219 1.00 83.15  ? 251 ARG B NH2 1 
ATOM 3532 N N   . LEU B 2 257 ? 94.941  126.869 144.024 1.00 83.61  ? 252 LEU B N   1 
ATOM 3533 C CA  . LEU B 2 257 ? 95.858  127.790 144.686 1.00 83.61  ? 252 LEU B CA  1 
ATOM 3534 C C   . LEU B 2 257 ? 95.479  127.888 146.154 1.00 83.61  ? 252 LEU B C   1 
ATOM 3535 O O   . LEU B 2 257 ? 94.397  128.378 146.485 1.00 83.61  ? 252 LEU B O   1 
ATOM 3536 C CB  . LEU B 2 257 ? 95.812  129.170 144.021 1.00 83.61  ? 252 LEU B CB  1 
ATOM 3537 C CG  . LEU B 2 257 ? 96.805  130.246 144.456 1.00 83.61  ? 252 LEU B CG  1 
ATOM 3538 C CD1 . LEU B 2 257 ? 97.255  131.052 143.256 1.00 83.61  ? 252 LEU B CD1 1 
ATOM 3539 C CD2 . LEU B 2 257 ? 96.183  131.160 145.488 1.00 83.61  ? 252 LEU B CD2 1 
ATOM 3540 N N   . PHE B 2 258 ? 96.368  127.431 147.029 1.00 86.92  ? 253 PHE B N   1 
ATOM 3541 C CA  . PHE B 2 258 ? 96.145  127.458 148.466 1.00 86.92  ? 253 PHE B CA  1 
ATOM 3542 C C   . PHE B 2 258 ? 96.914  128.608 149.106 1.00 86.92  ? 253 PHE B C   1 
ATOM 3543 O O   . PHE B 2 258 ? 97.810  129.203 148.503 1.00 86.92  ? 253 PHE B O   1 
ATOM 3544 C CB  . PHE B 2 258 ? 96.563  126.133 149.113 1.00 86.92  ? 253 PHE B CB  1 
ATOM 3545 C CG  . PHE B 2 258 ? 95.865  124.926 148.553 1.00 86.92  ? 253 PHE B CG  1 
ATOM 3546 C CD1 . PHE B 2 258 ? 94.513  124.729 148.766 1.00 86.92  ? 253 PHE B CD1 1 
ATOM 3547 C CD2 . PHE B 2 258 ? 96.565  123.980 147.833 1.00 86.92  ? 253 PHE B CD2 1 
ATOM 3548 C CE1 . PHE B 2 258 ? 93.874  123.618 148.261 1.00 86.92  ? 253 PHE B CE1 1 
ATOM 3549 C CE2 . PHE B 2 258 ? 95.930  122.868 147.327 1.00 86.92  ? 253 PHE B CE2 1 
ATOM 3550 C CZ  . PHE B 2 258 ? 94.583  122.688 147.541 1.00 86.92  ? 253 PHE B CZ  1 
ATOM 3551 N N   . ASP B 2 259 ? 96.547  128.913 150.348 1.00 95.70  ? 254 ASP B N   1 
ATOM 3552 C CA  . ASP B 2 259 ? 97.290  129.848 151.180 1.00 95.70  ? 254 ASP B CA  1 
ATOM 3553 C C   . ASP B 2 259 ? 97.442  129.242 152.567 1.00 95.70  ? 254 ASP B C   1 
ATOM 3554 O O   . ASP B 2 259 ? 96.668  128.373 152.974 1.00 95.70  ? 254 ASP B O   1 
ATOM 3555 C CB  . ASP B 2 259 ? 96.610  131.219 151.253 1.00 95.70  ? 254 ASP B CB  1 
ATOM 3556 C CG  . ASP B 2 259 ? 95.142  131.123 151.593 1.00 95.70  ? 254 ASP B CG  1 
ATOM 3557 O OD1 . ASP B 2 259 ? 94.593  130.002 151.561 1.00 95.70  ? 254 ASP B OD1 1 
ATOM 3558 O OD2 . ASP B 2 259 ? 94.531  132.174 151.879 1.00 95.70  ? 254 ASP B OD2 1 
ATOM 3559 N N   . LEU B 2 260 ? 98.457  129.708 153.294 1.00 96.25  ? 255 LEU B N   1 
ATOM 3560 C CA  . LEU B 2 260 ? 98.884  129.009 154.499 1.00 96.25  ? 255 LEU B CA  1 
ATOM 3561 C C   . LEU B 2 260 ? 98.202  129.515 155.761 1.00 96.25  ? 255 LEU B C   1 
ATOM 3562 O O   . LEU B 2 260 ? 97.708  128.709 156.557 1.00 96.25  ? 255 LEU B O   1 
ATOM 3563 C CB  . LEU B 2 260 ? 100.400 129.117 154.654 1.00 96.25  ? 255 LEU B CB  1 
ATOM 3564 C CG  . LEU B 2 260 ? 101.177 128.397 153.556 1.00 96.25  ? 255 LEU B CG  1 
ATOM 3565 C CD1 . LEU B 2 260 ? 102.670 128.651 153.683 1.00 96.25  ? 255 LEU B CD1 1 
ATOM 3566 C CD2 . LEU B 2 260 ? 100.860 126.916 153.575 1.00 96.25  ? 255 LEU B CD2 1 
ATOM 3567 N N   . ARG B 2 261 ? 98.167  130.832 155.971 1.00 106.05 ? 256 ARG B N   1 
ATOM 3568 C CA  . ARG B 2 261 ? 97.566  131.364 157.191 1.00 106.05 ? 256 ARG B CA  1 
ATOM 3569 C C   . ARG B 2 261 ? 96.067  131.102 157.233 1.00 106.05 ? 256 ARG B C   1 
ATOM 3570 O O   . ARG B 2 261 ? 95.515  130.795 158.295 1.00 106.05 ? 256 ARG B O   1 
ATOM 3571 C CB  . ARG B 2 261 ? 97.857  132.858 157.315 1.00 106.05 ? 256 ARG B CB  1 
ATOM 3572 C CG  . ARG B 2 261 ? 99.286  133.169 157.720 1.00 106.05 ? 256 ARG B CG  1 
ATOM 3573 C CD  . ARG B 2 261 ? 99.601  134.647 157.578 1.00 106.05 ? 256 ARG B CD  1 
ATOM 3574 N NE  . ARG B 2 261 ? 99.699  135.060 156.183 1.00 106.05 ? 256 ARG B NE  1 
ATOM 3575 C CZ  . ARG B 2 261 ? 99.873  136.316 155.790 1.00 106.05 ? 256 ARG B CZ  1 
ATOM 3576 N NH1 . ARG B 2 261 ? 99.974  137.285 156.689 1.00 106.05 ? 256 ARG B NH1 1 
ATOM 3577 N NH2 . ARG B 2 261 ? 99.952  136.605 154.498 1.00 106.05 ? 256 ARG B NH2 1 
ATOM 3578 N N   . ALA B 2 262 ? 95.389  131.219 156.091 1.00 106.10 ? 257 ALA B N   1 
ATOM 3579 C CA  . ALA B 2 262 ? 93.952  130.992 156.050 1.00 106.10 ? 257 ALA B CA  1 
ATOM 3580 C C   . ALA B 2 262 ? 93.586  129.518 156.120 1.00 106.10 ? 257 ALA B C   1 
ATOM 3581 O O   . ALA B 2 262 ? 92.488  129.194 156.585 1.00 106.10 ? 257 ALA B O   1 
ATOM 3582 C CB  . ALA B 2 262 ? 93.355  131.608 154.785 1.00 106.10 ? 257 ALA B CB  1 
ATOM 3583 N N   . ASP B 2 263 ? 94.471  128.629 155.677 1.00 106.95 ? 258 ASP B N   1 
ATOM 3584 C CA  . ASP B 2 263 ? 94.239  127.186 155.703 1.00 106.95 ? 258 ASP B CA  1 
ATOM 3585 C C   . ASP B 2 263 ? 92.940  126.837 154.975 1.00 106.95 ? 258 ASP B C   1 
ATOM 3586 O O   . ASP B 2 263 ? 92.029  126.211 155.518 1.00 106.95 ? 258 ASP B O   1 
ATOM 3587 C CB  . ASP B 2 263 ? 94.234  126.668 157.145 1.00 106.95 ? 258 ASP B CB  1 
ATOM 3588 C CG  . ASP B 2 263 ? 94.286  125.156 157.226 1.00 106.95 ? 258 ASP B CG  1 
ATOM 3589 O OD1 . ASP B 2 263 ? 94.357  124.497 156.168 1.00 106.95 ? 258 ASP B OD1 1 
ATOM 3590 O OD2 . ASP B 2 263 ? 94.258  124.623 158.356 1.00 106.95 ? 258 ASP B OD2 1 
ATOM 3591 N N   . GLN B 2 264 ? 92.874  127.264 153.717 1.00 103.76 ? 259 GLN B N   1 
ATOM 3592 C CA  . GLN B 2 264 ? 91.670  127.138 152.907 1.00 103.76 ? 259 GLN B CA  1 
ATOM 3593 C C   . GLN B 2 264 ? 92.075  126.773 151.484 1.00 103.76 ? 259 GLN B C   1 
ATOM 3594 O O   . GLN B 2 264 ? 93.218  126.394 151.215 1.00 103.76 ? 259 GLN B O   1 
ATOM 3595 C CB  . GLN B 2 264 ? 90.857  128.437 152.949 1.00 103.76 ? 259 GLN B CB  1 
ATOM 3596 C CG  . GLN B 2 264 ? 89.933  128.565 154.139 1.00 103.76 ? 259 GLN B CG  1 
ATOM 3597 C CD  . GLN B 2 264 ? 88.739  127.648 154.036 1.00 103.76 ? 259 GLN B CD  1 
ATOM 3598 O OE1 . GLN B 2 264 ? 88.169  127.237 155.047 1.00 103.76 ? 259 GLN B OE1 1 
ATOM 3599 N NE2 . GLN B 2 264 ? 88.356  127.310 152.815 1.00 103.76 ? 259 GLN B NE2 1 
ATOM 3600 N N   . GLU B 2 265 ? 91.116  126.885 150.568 1.00 95.30  ? 260 GLU B N   1 
ATOM 3601 C CA  . GLU B 2 265 ? 91.339  126.712 149.139 1.00 95.30  ? 260 GLU B CA  1 
ATOM 3602 C C   . GLU B 2 265 ? 90.641  127.855 148.417 1.00 95.30  ? 260 GLU B C   1 
ATOM 3603 O O   . GLU B 2 265 ? 89.430  128.041 148.575 1.00 95.30  ? 260 GLU B O   1 
ATOM 3604 C CB  . GLU B 2 265 ? 90.810  125.359 148.659 1.00 95.30  ? 260 GLU B CB  1 
ATOM 3605 C CG  . GLU B 2 265 ? 90.747  125.204 147.152 1.00 95.30  ? 260 GLU B CG  1 
ATOM 3606 C CD  . GLU B 2 265 ? 90.020  123.941 146.734 1.00 95.30  ? 260 GLU B CD  1 
ATOM 3607 O OE1 . GLU B 2 265 ? 89.753  123.091 147.608 1.00 95.30  ? 260 GLU B OE1 1 
ATOM 3608 O OE2 . GLU B 2 265 ? 89.701  123.805 145.534 1.00 95.30  ? 260 GLU B OE2 1 
ATOM 3609 N N   . LEU B 2 266 ? 91.398  128.617 147.630 1.00 91.84  ? 261 LEU B N   1 
ATOM 3610 C CA  . LEU B 2 266 ? 90.909  129.907 147.157 1.00 91.84  ? 261 LEU B CA  1 
ATOM 3611 C C   . LEU B 2 266 ? 90.255  129.864 145.780 1.00 91.84  ? 261 LEU B C   1 
ATOM 3612 O O   . LEU B 2 266 ? 89.077  130.209 145.648 1.00 91.84  ? 261 LEU B O   1 
ATOM 3613 C CB  . LEU B 2 266 ? 92.052  130.920 147.159 1.00 91.84  ? 261 LEU B CB  1 
ATOM 3614 C CG  . LEU B 2 266 ? 92.563  131.297 148.551 1.00 91.84  ? 261 LEU B CG  1 
ATOM 3615 C CD1 . LEU B 2 266 ? 93.365  132.585 148.504 1.00 91.84  ? 261 LEU B CD1 1 
ATOM 3616 C CD2 . LEU B 2 266 ? 91.410  131.418 149.533 1.00 91.84  ? 261 LEU B CD2 1 
ATOM 3617 N N   . MET B 2 267 ? 90.992  129.458 144.748 1.00 92.99  ? 262 MET B N   1 
ATOM 3618 C CA  . MET B 2 267 ? 90.497  129.528 143.379 1.00 92.99  ? 262 MET B CA  1 
ATOM 3619 C C   . MET B 2 267 ? 90.764  128.230 142.631 1.00 92.99  ? 262 MET B C   1 
ATOM 3620 O O   . MET B 2 267 ? 91.692  127.483 142.957 1.00 92.99  ? 262 MET B O   1 
ATOM 3621 C CB  . MET B 2 267 ? 91.132  130.693 142.616 1.00 92.99  ? 262 MET B CB  1 
ATOM 3622 C CG  . MET B 2 267 ? 90.750  132.054 143.153 1.00 92.99  ? 262 MET B CG  1 
ATOM 3623 S SD  . MET B 2 267 ? 88.976  132.364 143.070 1.00 92.99  ? 262 MET B SD  1 
ATOM 3624 C CE  . MET B 2 267 ? 88.733  132.502 141.302 1.00 92.99  ? 262 MET B CE  1 
ATOM 3625 N N   . THR B 2 268 ? 89.937  127.973 141.621 1.00 87.23  ? 263 THR B N   1 
ATOM 3626 C CA  . THR B 2 268 ? 90.041  126.788 140.780 1.00 87.23  ? 263 THR B CA  1 
ATOM 3627 C C   . THR B 2 268 ? 89.954  127.215 139.322 1.00 87.23  ? 263 THR B C   1 
ATOM 3628 O O   . THR B 2 268 ? 89.002  127.895 138.928 1.00 87.23  ? 263 THR B O   1 
ATOM 3629 C CB  . THR B 2 268 ? 88.936  125.784 141.105 1.00 87.23  ? 263 THR B CB  1 
ATOM 3630 O OG1 . THR B 2 268 ? 89.021  125.409 142.486 1.00 87.23  ? 263 THR B OG1 1 
ATOM 3631 C CG2 . THR B 2 268 ? 89.073  124.544 140.237 1.00 87.23  ? 263 THR B CG2 1 
ATOM 3632 N N   . TYR B 2 269 ? 90.941  126.812 138.526 1.00 86.22  ? 264 TYR B N   1 
ATOM 3633 C CA  . TYR B 2 269 ? 91.018  127.183 137.114 1.00 86.22  ? 264 TYR B CA  1 
ATOM 3634 C C   . TYR B 2 269 ? 90.434  126.039 136.295 1.00 86.22  ? 264 TYR B C   1 
ATOM 3635 O O   . TYR B 2 269 ? 91.160  125.226 135.725 1.00 86.22  ? 264 TYR B O   1 
ATOM 3636 C CB  . TYR B 2 269 ? 92.454  127.484 136.708 1.00 86.22  ? 264 TYR B CB  1 
ATOM 3637 C CG  . TYR B 2 269 ? 93.199  128.393 137.657 1.00 86.22  ? 264 TYR B CG  1 
ATOM 3638 C CD1 . TYR B 2 269 ? 93.010  129.763 137.630 1.00 86.22  ? 264 TYR B CD1 1 
ATOM 3639 C CD2 . TYR B 2 269 ? 94.100  127.877 138.577 1.00 86.22  ? 264 TYR B CD2 1 
ATOM 3640 C CE1 . TYR B 2 269 ? 93.692  130.592 138.494 1.00 86.22  ? 264 TYR B CE1 1 
ATOM 3641 C CE2 . TYR B 2 269 ? 94.787  128.700 139.444 1.00 86.22  ? 264 TYR B CE2 1 
ATOM 3642 C CZ  . TYR B 2 269 ? 94.579  130.056 139.398 1.00 86.22  ? 264 TYR B CZ  1 
ATOM 3643 O OH  . TYR B 2 269 ? 95.259  130.880 140.260 1.00 86.22  ? 264 TYR B OH  1 
ATOM 3644 N N   . SER B 2 270 ? 89.109  125.983 136.229 1.00 90.68  ? 265 SER B N   1 
ATOM 3645 C CA  . SER B 2 270 ? 88.404  124.904 135.554 1.00 90.68  ? 265 SER B CA  1 
ATOM 3646 C C   . SER B 2 270 ? 87.902  125.373 134.197 1.00 90.68  ? 265 SER B C   1 
ATOM 3647 O O   . SER B 2 270 ? 87.414  126.498 134.058 1.00 90.68  ? 265 SER B O   1 
ATOM 3648 C CB  . SER B 2 270 ? 87.227  124.406 136.396 1.00 90.68  ? 265 SER B CB  1 
ATOM 3649 O OG  . SER B 2 270 ? 86.230  125.405 136.523 1.00 90.68  ? 265 SER B OG  1 
ATOM 3650 N N   . HIS B 2 271 ? 88.030  124.504 133.198 1.00 96.91  ? 266 HIS B N   1 
ATOM 3651 C CA  . HIS B 2 271 ? 87.512  124.749 131.861 1.00 96.91  ? 266 HIS B CA  1 
ATOM 3652 C C   . HIS B 2 271 ? 86.892  123.467 131.322 1.00 96.91  ? 266 HIS B C   1 
ATOM 3653 O O   . HIS B 2 271 ? 87.447  122.378 131.497 1.00 96.91  ? 266 HIS B O   1 
ATOM 3654 C CB  . HIS B 2 271 ? 88.614  125.238 130.922 1.00 96.91  ? 266 HIS B CB  1 
ATOM 3655 C CG  . HIS B 2 271 ? 88.114  126.082 129.794 1.00 96.91  ? 266 HIS B CG  1 
ATOM 3656 N ND1 . HIS B 2 271 ? 87.582  125.544 128.641 1.00 96.91  ? 266 HIS B ND1 1 
ATOM 3657 C CD2 . HIS B 2 271 ? 88.072  127.426 129.636 1.00 96.91  ? 266 HIS B CD2 1 
ATOM 3658 C CE1 . HIS B 2 271 ? 87.230  126.521 127.824 1.00 96.91  ? 266 HIS B CE1 1 
ATOM 3659 N NE2 . HIS B 2 271 ? 87.517  127.673 128.404 1.00 96.91  ? 266 HIS B NE2 1 
ATOM 3660 N N   . ASP B 2 272 ? 85.735  123.600 130.670 1.00 97.19  ? 267 ASP B N   1 
ATOM 3661 C CA  . ASP B 2 272 ? 84.997  122.416 130.236 1.00 97.19  ? 267 ASP B CA  1 
ATOM 3662 C C   . ASP B 2 272 ? 85.567  121.839 128.947 1.00 97.19  ? 267 ASP B C   1 
ATOM 3663 O O   . ASP B 2 272 ? 85.284  120.688 128.601 1.00 97.19  ? 267 ASP B O   1 
ATOM 3664 C CB  . ASP B 2 272 ? 83.519  122.756 130.063 1.00 97.19  ? 267 ASP B CB  1 
ATOM 3665 C CG  . ASP B 2 272 ? 82.801  122.915 131.384 1.00 97.19  ? 267 ASP B CG  1 
ATOM 3666 O OD1 . ASP B 2 272 ? 83.206  122.254 132.362 1.00 97.19  ? 267 ASP B OD1 1 
ATOM 3667 O OD2 . ASP B 2 272 ? 81.833  123.701 131.445 1.00 97.19  ? 267 ASP B OD2 1 
ATOM 3668 N N   . ASN B 2 273 ? 86.358  122.623 128.216 1.00 95.56  ? 268 ASN B N   1 
ATOM 3669 C CA  . ASN B 2 273 ? 86.938  122.121 126.974 1.00 95.56  ? 268 ASN B CA  1 
ATOM 3670 C C   . ASN B 2 273 ? 88.100  121.173 127.256 1.00 95.56  ? 268 ASN B C   1 
ATOM 3671 O O   . ASN B 2 273 ? 88.218  120.121 126.617 1.00 95.56  ? 268 ASN B O   1 
ATOM 3672 C CB  . ASN B 2 273 ? 87.377  123.300 126.101 1.00 95.56  ? 268 ASN B CB  1 
ATOM 3673 C CG  . ASN B 2 273 ? 87.861  122.878 124.716 1.00 95.56  ? 268 ASN B CG  1 
ATOM 3674 O OD1 . ASN B 2 273 ? 88.496  121.838 124.541 1.00 95.56  ? 268 ASN B OD1 1 
ATOM 3675 N ND2 . ASN B 2 273 ? 87.553  123.699 123.719 1.00 95.56  ? 268 ASN B ND2 1 
ATOM 3676 N N   . ILE B 2 274 ? 88.956  121.517 128.215 1.00 90.71  ? 269 ILE B N   1 
ATOM 3677 C CA  . ILE B 2 274 ? 90.160  120.738 128.485 1.00 90.71  ? 269 ILE B CA  1 
ATOM 3678 C C   . ILE B 2 274 ? 89.790  119.488 129.272 1.00 90.71  ? 269 ILE B C   1 
ATOM 3679 O O   . ILE B 2 274 ? 89.001  119.546 130.223 1.00 90.71  ? 269 ILE B O   1 
ATOM 3680 C CB  . ILE B 2 274 ? 91.196  121.582 129.242 1.00 90.71  ? 269 ILE B CB  1 
ATOM 3681 C CG1 . ILE B 2 274 ? 90.549  122.277 130.436 1.00 90.71  ? 269 ILE B CG1 1 
ATOM 3682 C CG2 . ILE B 2 274 ? 91.814  122.612 128.320 1.00 90.71  ? 269 ILE B CG2 1 
ATOM 3683 C CD1 . ILE B 2 274 ? 91.529  122.674 131.518 1.00 90.71  ? 269 ILE B CD1 1 
ATOM 3684 N N   . ILE B 2 275 ? 90.354  118.351 128.873 1.00 88.69  ? 270 ILE B N   1 
ATOM 3685 C CA  . ILE B 2 275 ? 90.111  117.084 129.554 1.00 88.69  ? 270 ILE B CA  1 
ATOM 3686 C C   . ILE B 2 275 ? 91.393  116.421 130.036 1.00 88.69  ? 270 ILE B C   1 
ATOM 3687 O O   . ILE B 2 275 ? 91.358  115.702 131.047 1.00 88.69  ? 270 ILE B O   1 
ATOM 3688 C CB  . ILE B 2 275 ? 89.316  116.114 128.651 1.00 88.69  ? 270 ILE B CB  1 
ATOM 3689 C CG1 . ILE B 2 275 ? 87.979  116.736 128.254 1.00 88.69  ? 270 ILE B CG1 1 
ATOM 3690 C CG2 . ILE B 2 275 ? 89.056  114.791 129.350 1.00 88.69  ? 270 ILE B CG2 1 
ATOM 3691 C CD1 . ILE B 2 275 ? 87.078  117.043 129.428 1.00 88.69  ? 270 ILE B CD1 1 
ATOM 3692 N N   . CYS B 2 276 ? 92.528  116.676 129.393 1.00 83.57  ? 271 CYS B N   1 
ATOM 3693 C CA  . CYS B 2 276 ? 93.791  116.069 129.773 1.00 83.57  ? 271 CYS B CA  1 
ATOM 3694 C C   . CYS B 2 276 ? 94.275  116.622 131.114 1.00 83.57  ? 271 CYS B C   1 
ATOM 3695 O O   . CYS B 2 276 ? 93.676  117.526 131.699 1.00 83.57  ? 271 CYS B O   1 
ATOM 3696 C CB  . CYS B 2 276 ? 94.836  116.311 128.691 1.00 83.57  ? 271 CYS B CB  1 
ATOM 3697 S SG  . CYS B 2 276 ? 95.260  118.051 128.467 1.00 83.57  ? 271 CYS B SG  1 
ATOM 3698 N N   . GLY B 2 277 ? 95.390  116.072 131.597 1.00 78.19  ? 272 GLY B N   1 
ATOM 3699 C CA  . GLY B 2 277 ? 95.915  116.420 132.899 1.00 78.19  ? 272 GLY B CA  1 
ATOM 3700 C C   . GLY B 2 277 ? 97.072  117.412 132.848 1.00 78.19  ? 272 GLY B C   1 
ATOM 3701 O O   . GLY B 2 277 ? 97.679  117.659 131.811 1.00 78.19  ? 272 GLY B O   1 
ATOM 3702 N N   . ILE B 2 278 ? 97.357  117.994 134.013 1.00 68.97  ? 273 ILE B N   1 
ATOM 3703 C CA  . ILE B 2 278 ? 98.477  118.914 134.144 1.00 68.97  ? 273 ILE B CA  1 
ATOM 3704 C C   . ILE B 2 278 ? 99.769  118.129 134.346 1.00 68.97  ? 273 ILE B C   1 
ATOM 3705 O O   . ILE B 2 278 ? 99.770  116.990 134.815 1.00 68.97  ? 273 ILE B O   1 
ATOM 3706 C CB  . ILE B 2 278 ? 98.245  119.909 135.291 1.00 68.97  ? 273 ILE B CB  1 
ATOM 3707 N N   . THR B 2 279 ? 100.888 118.750 133.978 1.00 69.07  ? 274 THR B N   1 
ATOM 3708 C CA  . THR B 2 279 ? 102.180 118.088 134.087 1.00 69.07  ? 274 THR B CA  1 
ATOM 3709 C C   . THR B 2 279 ? 103.295 118.966 134.641 1.00 69.07  ? 274 THR B C   1 
ATOM 3710 O O   . THR B 2 279 ? 104.404 118.458 134.827 1.00 69.07  ? 274 THR B O   1 
ATOM 3711 C CB  . THR B 2 279 ? 102.612 117.548 132.721 1.00 69.07  ? 274 THR B CB  1 
ATOM 3712 O OG1 . THR B 2 279 ? 103.820 116.794 132.867 1.00 69.07  ? 274 THR B OG1 1 
ATOM 3713 C CG2 . THR B 2 279 ? 102.847 118.697 131.758 1.00 69.07  ? 274 THR B CG2 1 
ATOM 3714 N N   . SER B 2 280 ? 103.048 120.246 134.908 1.00 69.53  ? 275 SER B N   1 
ATOM 3715 C CA  . SER B 2 280 ? 104.007 121.135 135.554 1.00 69.53  ? 275 SER B CA  1 
ATOM 3716 C C   . SER B 2 280 ? 103.328 122.468 135.824 1.00 69.53  ? 275 SER B C   1 
ATOM 3717 O O   . SER B 2 280 ? 102.391 122.849 135.117 1.00 69.53  ? 275 SER B O   1 
ATOM 3718 C CB  . SER B 2 280 ? 105.256 121.353 134.694 1.00 69.53  ? 275 SER B CB  1 
ATOM 3719 O OG  . SER B 2 280 ? 106.021 120.165 134.597 1.00 69.53  ? 275 SER B OG  1 
ATOM 3720 N N   . VAL B 2 281 ? 103.815 123.174 136.843 1.00 71.21  ? 276 VAL B N   1 
ATOM 3721 C CA  . VAL B 2 281 ? 103.298 124.487 137.219 1.00 71.21  ? 276 VAL B CA  1 
ATOM 3722 C C   . VAL B 2 281 ? 104.456 125.343 137.715 1.00 71.21  ? 276 VAL B C   1 
ATOM 3723 O O   . VAL B 2 281 ? 105.302 124.874 138.483 1.00 71.21  ? 276 VAL B O   1 
ATOM 3724 C CB  . VAL B 2 281 ? 102.199 124.384 138.299 1.00 71.21  ? 276 VAL B CB  1 
ATOM 3725 C CG1 . VAL B 2 281 ? 101.910 125.745 138.902 1.00 71.21  ? 276 VAL B CG1 1 
ATOM 3726 C CG2 . VAL B 2 281 ? 100.924 123.797 137.722 1.00 71.21  ? 276 VAL B CG2 1 
ATOM 3727 N N   . SER B 2 282 ? 104.496 126.600 137.275 1.00 72.12  ? 277 SER B N   1 
ATOM 3728 C CA  . SER B 2 282 ? 105.504 127.544 137.736 1.00 72.12  ? 277 SER B CA  1 
ATOM 3729 C C   . SER B 2 282 ? 104.932 128.951 137.662 1.00 72.12  ? 277 SER B C   1 
ATOM 3730 O O   . SER B 2 282 ? 104.145 129.256 136.762 1.00 72.12  ? 277 SER B O   1 
ATOM 3731 C CB  . SER B 2 282 ? 106.785 127.444 136.904 1.00 72.12  ? 277 SER B CB  1 
ATOM 3732 O OG  . SER B 2 282 ? 106.528 127.725 135.540 1.00 72.12  ? 277 SER B OG  1 
ATOM 3733 N N   . PHE B 2 283 ? 105.328 129.797 138.606 1.00 73.98  ? 278 PHE B N   1 
ATOM 3734 C CA  . PHE B 2 283 ? 104.828 131.160 138.685 1.00 73.98  ? 278 PHE B CA  1 
ATOM 3735 C C   . PHE B 2 283 ? 105.741 132.099 137.901 1.00 73.98  ? 278 PHE B C   1 
ATOM 3736 O O   . PHE B 2 283 ? 106.619 131.668 137.150 1.00 73.98  ? 278 PHE B O   1 
ATOM 3737 C CB  . PHE B 2 283 ? 104.698 131.597 140.141 1.00 73.98  ? 278 PHE B CB  1 
ATOM 3738 C CG  . PHE B 2 283 ? 103.397 131.218 140.778 1.00 73.98  ? 278 PHE B CG  1 
ATOM 3739 C CD1 . PHE B 2 283 ? 102.294 132.039 140.670 1.00 73.98  ? 278 PHE B CD1 1 
ATOM 3740 C CD2 . PHE B 2 283 ? 103.280 130.047 141.497 1.00 73.98  ? 278 PHE B CD2 1 
ATOM 3741 C CE1 . PHE B 2 283 ? 101.102 131.697 141.256 1.00 73.98  ? 278 PHE B CE1 1 
ATOM 3742 C CE2 . PHE B 2 283 ? 102.088 129.699 142.085 1.00 73.98  ? 278 PHE B CE2 1 
ATOM 3743 C CZ  . PHE B 2 283 ? 100.997 130.528 141.964 1.00 73.98  ? 278 PHE B CZ  1 
ATOM 3744 N N   . SER B 2 284 ? 105.538 133.400 138.070 1.00 79.00  ? 279 SER B N   1 
ATOM 3745 C CA  . SER B 2 284 ? 106.349 134.426 137.439 1.00 79.00  ? 279 SER B CA  1 
ATOM 3746 C C   . SER B 2 284 ? 107.009 135.289 138.511 1.00 79.00  ? 279 SER B C   1 
ATOM 3747 O O   . SER B 2 284 ? 106.914 135.011 139.712 1.00 79.00  ? 279 SER B O   1 
ATOM 3748 C CB  . SER B 2 284 ? 105.495 135.261 136.486 1.00 79.00  ? 279 SER B CB  1 
ATOM 3749 O OG  . SER B 2 284 ? 106.249 136.323 135.934 1.00 79.00  ? 279 SER B OG  1 
ATOM 3750 N N   . LYS B 2 285 ? 107.687 136.349 138.072 1.00 81.76  ? 280 LYS B N   1 
ATOM 3751 C CA  . LYS B 2 285 ? 108.436 137.184 139.003 1.00 81.76  ? 280 LYS B CA  1 
ATOM 3752 C C   . LYS B 2 285 ? 107.506 138.056 139.834 1.00 81.76  ? 280 LYS B C   1 
ATOM 3753 O O   . LYS B 2 285 ? 107.740 138.268 141.030 1.00 81.76  ? 280 LYS B O   1 
ATOM 3754 C CB  . LYS B 2 285 ? 109.439 138.043 138.237 1.00 81.76  ? 280 LYS B CB  1 
ATOM 3755 C CG  . LYS B 2 285 ? 110.074 139.151 139.056 1.00 81.76  ? 280 LYS B CG  1 
ATOM 3756 C CD  . LYS B 2 285 ? 111.161 138.617 139.963 1.00 81.76  ? 280 LYS B CD  1 
ATOM 3757 C CE  . LYS B 2 285 ? 111.933 139.753 140.605 1.00 81.76  ? 280 LYS B CE  1 
ATOM 3758 N NZ  . LYS B 2 285 ? 112.603 140.602 139.583 1.00 81.76  ? 280 LYS B NZ  1 
ATOM 3759 N N   . SER B 2 286 ? 106.449 138.559 139.207 1.00 85.90  ? 281 SER B N   1 
ATOM 3760 C CA  . SER B 2 286 ? 105.531 139.471 139.888 1.00 85.90  ? 281 SER B CA  1 
ATOM 3761 C C   . SER B 2 286 ? 104.331 138.805 140.520 1.00 85.90  ? 281 SER B C   1 
ATOM 3762 O O   . SER B 2 286 ? 103.537 139.465 141.191 1.00 85.90  ? 281 SER B O   1 
ATOM 3763 C CB  . SER B 2 286 ? 105.023 140.480 138.862 1.00 85.90  ? 281 SER B CB  1 
ATOM 3764 O OG  . SER B 2 286 ? 103.744 140.982 139.211 1.00 85.90  ? 281 SER B OG  1 
ATOM 3765 N N   . GLY B 2 287 ? 104.183 137.504 140.325 1.00 83.74  ? 282 GLY B N   1 
ATOM 3766 C CA  . GLY B 2 287 ? 102.994 136.839 140.811 1.00 83.74  ? 282 GLY B CA  1 
ATOM 3767 C C   . GLY B 2 287 ? 101.726 137.214 140.087 1.00 83.74  ? 282 GLY B C   1 
ATOM 3768 O O   . GLY B 2 287 ? 100.674 137.324 140.719 1.00 83.74  ? 282 GLY B O   1 
ATOM 3769 N N   . ARG B 2 288 ? 101.789 137.401 138.775 1.00 82.13  ? 283 ARG B N   1 
ATOM 3770 C CA  . ARG B 2 288 ? 100.647 137.845 137.989 1.00 82.13  ? 283 ARG B CA  1 
ATOM 3771 C C   . ARG B 2 288 ? 100.223 136.827 136.943 1.00 82.13  ? 283 ARG B C   1 
ATOM 3772 O O   . ARG B 2 288 ? 99.049  136.786 136.565 1.00 82.13  ? 283 ARG B O   1 
ATOM 3773 C CB  . ARG B 2 288 ? 100.977 139.177 137.309 1.00 82.13  ? 283 ARG B CB  1 
ATOM 3774 C CG  . ARG B 2 288 ? 99.863  139.781 136.475 1.00 82.13  ? 283 ARG B CG  1 
ATOM 3775 C CD  . ARG B 2 288 ? 98.678  140.209 137.317 1.00 82.13  ? 283 ARG B CD  1 
ATOM 3776 N NE  . ARG B 2 288 ? 97.650  140.832 136.490 1.00 82.13  ? 283 ARG B NE  1 
ATOM 3777 C CZ  . ARG B 2 288 ? 96.436  141.156 136.916 1.00 82.13  ? 283 ARG B CZ  1 
ATOM 3778 N NH1 . ARG B 2 288 ? 96.088  140.919 138.166 1.00 82.13  ? 283 ARG B NH1 1 
ATOM 3779 N NH2 . ARG B 2 288 ? 95.570  141.720 136.088 1.00 82.13  ? 283 ARG B NH2 1 
ATOM 3780 N N   . LEU B 2 289 ? 101.145 135.996 136.475 1.00 79.65  ? 284 LEU B N   1 
ATOM 3781 C CA  . LEU B 2 289 ? 100.855 134.988 135.467 1.00 79.65  ? 284 LEU B CA  1 
ATOM 3782 C C   . LEU B 2 289 ? 101.251 133.614 135.985 1.00 79.65  ? 284 LEU B C   1 
ATOM 3783 O O   . LEU B 2 289 ? 102.361 133.434 136.497 1.00 79.65  ? 284 LEU B O   1 
ATOM 3784 C CB  . LEU B 2 289 ? 101.588 135.296 134.161 1.00 79.65  ? 284 LEU B CB  1 
ATOM 3785 C CG  . LEU B 2 289 ? 100.876 136.222 133.177 1.00 79.65  ? 284 LEU B CG  1 
ATOM 3786 C CD1 . LEU B 2 289 ? 100.918 137.652 133.666 1.00 79.65  ? 284 LEU B CD1 1 
ATOM 3787 C CD2 . LEU B 2 289 ? 101.504 136.117 131.803 1.00 79.65  ? 284 LEU B CD2 1 
ATOM 3788 N N   . LEU B 2 290 ? 100.341 132.653 135.850 1.00 75.62  ? 285 LEU B N   1 
ATOM 3789 C CA  . LEU B 2 290 ? 100.580 131.264 136.211 1.00 75.62  ? 285 LEU B CA  1 
ATOM 3790 C C   . LEU B 2 290 ? 100.712 130.446 134.937 1.00 75.62  ? 285 LEU B C   1 
ATOM 3791 O O   . LEU B 2 290 ? 99.851  130.524 134.054 1.00 75.62  ? 285 LEU B O   1 
ATOM 3792 C CB  . LEU B 2 290 ? 99.443  130.724 137.082 1.00 75.62  ? 285 LEU B CB  1 
ATOM 3793 C CG  . LEU B 2 290 ? 99.550  129.314 137.660 1.00 75.62  ? 285 LEU B CG  1 
ATOM 3794 C CD1 . LEU B 2 290 ? 98.863  129.265 139.005 1.00 75.62  ? 285 LEU B CD1 1 
ATOM 3795 C CD2 . LEU B 2 290 ? 98.933  128.286 136.735 1.00 75.62  ? 285 LEU B CD2 1 
ATOM 3796 N N   . LEU B 2 291 ? 101.783 129.668 134.839 1.00 72.36  ? 286 LEU B N   1 
ATOM 3797 C CA  . LEU B 2 291 ? 102.076 128.883 133.652 1.00 72.36  ? 286 LEU B CA  1 
ATOM 3798 C C   . LEU B 2 291 ? 101.985 127.401 133.982 1.00 72.36  ? 286 LEU B C   1 
ATOM 3799 O O   . LEU B 2 291 ? 102.464 126.961 135.031 1.00 72.36  ? 286 LEU B O   1 
ATOM 3800 C CB  . LEU B 2 291 ? 103.462 129.218 133.103 1.00 72.36  ? 286 LEU B CB  1 
ATOM 3801 C CG  . LEU B 2 291 ? 103.621 130.584 132.436 1.00 72.36  ? 286 LEU B CG  1 
ATOM 3802 C CD1 . LEU B 2 291 ? 103.989 131.643 133.451 1.00 72.36  ? 286 LEU B CD1 1 
ATOM 3803 C CD2 . LEU B 2 291 ? 104.661 130.522 131.338 1.00 72.36  ? 286 LEU B CD2 1 
ATOM 3804 N N   . ALA B 2 292 ? 101.370 126.634 133.086 1.00 71.93  ? 287 ALA B N   1 
ATOM 3805 C CA  . ALA B 2 292 ? 101.144 125.219 133.338 1.00 71.93  ? 287 ALA B CA  1 
ATOM 3806 C C   . ALA B 2 292 ? 101.179 124.443 132.033 1.00 71.93  ? 287 ALA B C   1 
ATOM 3807 O O   . ALA B 2 292 ? 100.592 124.877 131.039 1.00 71.93  ? 287 ALA B O   1 
ATOM 3808 C CB  . ALA B 2 292 ? 99.804  124.996 134.044 1.00 71.93  ? 287 ALA B CB  1 
ATOM 3809 N N   . GLY B 2 293 ? 101.865 123.299 132.044 1.00 72.37  ? 288 GLY B N   1 
ATOM 3810 C CA  . GLY B 2 293 ? 101.858 122.407 130.907 1.00 72.37  ? 288 GLY B CA  1 
ATOM 3811 C C   . GLY B 2 293 ? 100.746 121.376 130.988 1.00 72.37  ? 288 GLY B C   1 
ATOM 3812 O O   . GLY B 2 293 ? 100.236 121.069 132.063 1.00 72.37  ? 288 GLY B O   1 
ATOM 3813 N N   . TYR B 2 294 ? 100.372 120.836 129.832 1.00 72.31  ? 289 TYR B N   1 
ATOM 3814 C CA  . TYR B 2 294 ? 99.250  119.915 129.737 1.00 72.31  ? 289 TYR B CA  1 
ATOM 3815 C C   . TYR B 2 294 ? 99.626  118.728 128.864 1.00 72.31  ? 289 TYR B C   1 
ATOM 3816 O O   . TYR B 2 294 ? 100.640 118.735 128.163 1.00 72.31  ? 289 TYR B O   1 
ATOM 3817 C CB  . TYR B 2 294 ? 98.000  120.607 129.182 1.00 72.31  ? 289 TYR B CB  1 
ATOM 3818 C CG  . TYR B 2 294 ? 97.396  121.645 130.098 1.00 72.31  ? 289 TYR B CG  1 
ATOM 3819 C CD1 . TYR B 2 294 ? 97.983  122.889 130.252 1.00 72.31  ? 289 TYR B CD1 1 
ATOM 3820 C CD2 . TYR B 2 294 ? 96.231  121.387 130.797 1.00 72.31  ? 289 TYR B CD2 1 
ATOM 3821 C CE1 . TYR B 2 294 ? 97.435  123.839 131.082 1.00 72.31  ? 289 TYR B CE1 1 
ATOM 3822 C CE2 . TYR B 2 294 ? 95.677  122.333 131.629 1.00 72.31  ? 289 TYR B CE2 1 
ATOM 3823 C CZ  . TYR B 2 294 ? 96.281  123.554 131.768 1.00 72.31  ? 289 TYR B CZ  1 
ATOM 3824 O OH  . TYR B 2 294 ? 95.734  124.504 132.594 1.00 72.31  ? 289 TYR B OH  1 
ATOM 3825 N N   . ASP B 2 295 ? 98.785  117.693 128.918 1.00 78.26  ? 290 ASP B N   1 
ATOM 3826 C CA  . ASP B 2 295 ? 99.021  116.460 128.177 1.00 78.26  ? 290 ASP B CA  1 
ATOM 3827 C C   . ASP B 2 295 ? 98.678  116.577 126.699 1.00 78.26  ? 290 ASP B C   1 
ATOM 3828 O O   . ASP B 2 295 ? 99.094  115.720 125.913 1.00 78.26  ? 290 ASP B O   1 
ATOM 3829 C CB  . ASP B 2 295 ? 98.200  115.317 128.781 1.00 78.26  ? 290 ASP B CB  1 
ATOM 3830 C CG  . ASP B 2 295 ? 98.822  114.739 130.035 1.00 78.26  ? 290 ASP B CG  1 
ATOM 3831 O OD1 . ASP B 2 295 ? 99.780  113.952 129.920 1.00 78.26  ? 290 ASP B OD1 1 
ATOM 3832 O OD2 . ASP B 2 295 ? 98.342  115.060 131.141 1.00 78.26  ? 290 ASP B OD2 1 
ATOM 3833 N N   . ASP B 2 296 ? 97.931  117.609 126.299 1.00 81.02  ? 291 ASP B N   1 
ATOM 3834 C CA  . ASP B 2 296 ? 97.379  117.707 124.952 1.00 81.02  ? 291 ASP B CA  1 
ATOM 3835 C C   . ASP B 2 296 ? 98.244  118.536 124.013 1.00 81.02  ? 291 ASP B C   1 
ATOM 3836 O O   . ASP B 2 296 ? 97.711  119.261 123.164 1.00 81.02  ? 291 ASP B O   1 
ATOM 3837 C CB  . ASP B 2 296 ? 95.957  118.266 124.998 1.00 81.02  ? 291 ASP B CB  1 
ATOM 3838 C CG  . ASP B 2 296 ? 95.902  119.687 125.518 1.00 81.02  ? 291 ASP B CG  1 
ATOM 3839 O OD1 . ASP B 2 296 ? 96.889  120.141 126.134 1.00 81.02  ? 291 ASP B OD1 1 
ATOM 3840 O OD2 . ASP B 2 296 ? 94.870  120.354 125.307 1.00 81.02  ? 291 ASP B OD2 1 
ATOM 3841 N N   . PHE B 2 297 ? 99.566  118.462 124.161 1.00 81.12  ? 292 PHE B N   1 
ATOM 3842 C CA  . PHE B 2 297 ? 100.571 119.036 123.269 1.00 81.12  ? 292 PHE B CA  1 
ATOM 3843 C C   . PHE B 2 297 ? 100.677 120.552 123.381 1.00 81.12  ? 292 PHE B C   1 
ATOM 3844 O O   . PHE B 2 297 ? 101.382 121.164 122.570 1.00 81.12  ? 292 PHE B O   1 
ATOM 3845 C CB  . PHE B 2 297 ? 100.329 118.679 121.797 1.00 81.12  ? 292 PHE B CB  1 
ATOM 3846 C CG  . PHE B 2 297 ? 100.070 117.216 121.550 1.00 81.12  ? 292 PHE B CG  1 
ATOM 3847 C CD1 . PHE B 2 297 ? 101.117 116.352 121.315 1.00 81.12  ? 292 PHE B CD1 1 
ATOM 3848 C CD2 . PHE B 2 297 ? 98.780  116.719 121.504 1.00 81.12  ? 292 PHE B CD2 1 
ATOM 3849 C CE1 . PHE B 2 297 ? 100.890 115.012 121.075 1.00 81.12  ? 292 PHE B CE1 1 
ATOM 3850 C CE2 . PHE B 2 297 ? 98.543  115.380 121.266 1.00 81.12  ? 292 PHE B CE2 1 
ATOM 3851 C CZ  . PHE B 2 297 ? 99.602  114.526 121.049 1.00 81.12  ? 292 PHE B CZ  1 
ATOM 3852 N N   . ASN B 2 298 ? 100.017 121.182 124.347 1.00 77.40  ? 293 ASN B N   1 
ATOM 3853 C CA  . ASN B 2 298 ? 100.018 122.632 124.454 1.00 77.40  ? 293 ASN B CA  1 
ATOM 3854 C C   . ASN B 2 298 ? 100.251 123.058 125.896 1.00 77.40  ? 293 ASN B C   1 
ATOM 3855 O O   . ASN B 2 298 ? 99.953  122.325 126.842 1.00 77.40  ? 293 ASN B O   1 
ATOM 3856 C CB  . ASN B 2 298 ? 98.699  123.231 123.945 1.00 77.40  ? 293 ASN B CB  1 
ATOM 3857 N N   . CYS B 2 299 ? 100.790 124.262 126.048 1.00 77.70  ? 294 CYS B N   1 
ATOM 3858 C CA  . CYS B 2 299 ? 100.924 124.918 127.338 1.00 77.70  ? 294 CYS B CA  1 
ATOM 3859 C C   . CYS B 2 299 ? 99.961  126.093 127.403 1.00 77.70  ? 294 CYS B C   1 
ATOM 3860 O O   . CYS B 2 299 ? 99.488  126.585 126.374 1.00 77.70  ? 294 CYS B O   1 
ATOM 3861 C CB  . CYS B 2 299 ? 102.355 125.401 127.573 1.00 77.70  ? 294 CYS B CB  1 
ATOM 3862 S SG  . CYS B 2 299 ? 102.516 126.554 128.946 1.00 77.70  ? 294 CYS B SG  1 
ATOM 3863 N N   . ASN B 2 300 ? 99.671  126.546 128.618 1.00 78.37  ? 295 ASN B N   1 
ATOM 3864 C CA  . ASN B 2 300 ? 98.667  127.575 128.825 1.00 78.37  ? 295 ASN B CA  1 
ATOM 3865 C C   . ASN B 2 300 ? 99.173  128.625 129.804 1.00 78.37  ? 295 ASN B C   1 
ATOM 3866 O O   . ASN B 2 300 ? 100.115 128.396 130.567 1.00 78.37  ? 295 ASN B O   1 
ATOM 3867 C CB  . ASN B 2 300 ? 97.350  126.983 129.335 1.00 78.37  ? 295 ASN B CB  1 
ATOM 3868 C CG  . ASN B 2 300 ? 96.475  126.467 128.216 1.00 78.37  ? 295 ASN B CG  1 
ATOM 3869 O OD1 . ASN B 2 300 ? 96.539  126.954 127.089 1.00 78.37  ? 295 ASN B OD1 1 
ATOM 3870 N ND2 . ASN B 2 300 ? 95.643  125.480 128.522 1.00 78.37  ? 295 ASN B ND2 1 
ATOM 3871 N N   . VAL B 2 301 ? 98.525  129.785 129.766 1.00 78.46  ? 296 VAL B N   1 
ATOM 3872 C CA  . VAL B 2 301 ? 98.840  130.915 130.628 1.00 78.46  ? 296 VAL B CA  1 
ATOM 3873 C C   . VAL B 2 301 ? 97.560  131.327 131.340 1.00 78.46  ? 296 VAL B C   1 
ATOM 3874 O O   . VAL B 2 301 ? 96.510  131.463 130.701 1.00 78.46  ? 296 VAL B O   1 
ATOM 3875 C CB  . VAL B 2 301 ? 99.419  132.096 129.833 1.00 78.46  ? 296 VAL B CB  1 
ATOM 3876 C CG1 . VAL B 2 301 ? 99.581  133.304 130.726 1.00 78.46  ? 296 VAL B CG1 1 
ATOM 3877 C CG2 . VAL B 2 301 ? 100.747 131.713 129.210 1.00 78.46  ? 296 VAL B CG2 1 
ATOM 3878 N N   . TRP B 2 302 ? 97.643  131.526 132.652 1.00 78.34  ? 297 TRP B N   1 
ATOM 3879 C CA  . TRP B 2 302 ? 96.491  131.900 133.454 1.00 78.34  ? 297 TRP B CA  1 
ATOM 3880 C C   . TRP B 2 302 ? 96.807  133.138 134.282 1.00 78.34  ? 297 TRP B C   1 
ATOM 3881 O O   . TRP B 2 302 ? 97.963  133.413 134.612 1.00 78.34  ? 297 TRP B O   1 
ATOM 3882 C CB  . TRP B 2 302 ? 96.063  130.758 134.380 1.00 78.34  ? 297 TRP B CB  1 
ATOM 3883 C CG  . TRP B 2 302 ? 95.612  129.521 133.666 1.00 78.34  ? 297 TRP B CG  1 
ATOM 3884 C CD1 . TRP B 2 302 ? 96.402  128.582 133.075 1.00 78.34  ? 297 TRP B CD1 1 
ATOM 3885 C CD2 . TRP B 2 302 ? 94.262  129.084 133.479 1.00 78.34  ? 297 TRP B CD2 1 
ATOM 3886 N NE1 . TRP B 2 302 ? 95.628  127.589 132.527 1.00 78.34  ? 297 TRP B NE1 1 
ATOM 3887 C CE2 . TRP B 2 302 ? 94.311  127.875 132.762 1.00 78.34  ? 297 TRP B CE2 1 
ATOM 3888 C CE3 . TRP B 2 302 ? 93.018  129.600 133.846 1.00 78.34  ? 297 TRP B CE3 1 
ATOM 3889 C CZ2 . TRP B 2 302 ? 93.167  127.177 132.405 1.00 78.34  ? 297 TRP B CZ2 1 
ATOM 3890 C CZ3 . TRP B 2 302 ? 91.884  128.905 133.491 1.00 78.34  ? 297 TRP B CZ3 1 
ATOM 3891 C CH2 . TRP B 2 302 ? 91.964  127.708 132.778 1.00 78.34  ? 297 TRP B CH2 1 
ATOM 3892 N N   . ASP B 2 303 ? 95.764  133.889 134.614 1.00 83.68  ? 298 ASP B N   1 
ATOM 3893 C CA  . ASP B 2 303 ? 95.867  135.064 135.477 1.00 83.68  ? 298 ASP B CA  1 
ATOM 3894 C C   . ASP B 2 303 ? 95.294  134.682 136.837 1.00 83.68  ? 298 ASP B C   1 
ATOM 3895 O O   . ASP B 2 303 ? 94.097  134.410 136.962 1.00 83.68  ? 298 ASP B O   1 
ATOM 3896 C CB  . ASP B 2 303 ? 95.140  136.258 134.873 1.00 83.68  ? 298 ASP B CB  1 
ATOM 3897 C CG  . ASP B 2 303 ? 94.970  137.395 135.859 1.00 83.68  ? 298 ASP B CG  1 
ATOM 3898 O OD1 . ASP B 2 303 ? 95.965  137.766 136.518 1.00 83.68  ? 298 ASP B OD1 1 
ATOM 3899 O OD2 . ASP B 2 303 ? 93.846  137.924 135.970 1.00 83.68  ? 298 ASP B OD2 1 
ATOM 3900 N N   . ALA B 2 304 ? 96.156  134.664 137.854 1.00 85.29  ? 299 ALA B N   1 
ATOM 3901 C CA  . ALA B 2 304 ? 95.797  134.045 139.126 1.00 85.29  ? 299 ALA B CA  1 
ATOM 3902 C C   . ALA B 2 304 ? 94.668  134.787 139.827 1.00 85.29  ? 299 ALA B C   1 
ATOM 3903 O O   . ALA B 2 304 ? 93.748  134.160 140.367 1.00 85.29  ? 299 ALA B O   1 
ATOM 3904 C CB  . ALA B 2 304 ? 97.022  133.967 140.033 1.00 85.29  ? 299 ALA B CB  1 
ATOM 3905 N N   . LEU B 2 305 ? 94.715  136.119 139.837 1.00 90.55  ? 300 LEU B N   1 
ATOM 3906 C CA  . LEU B 2 305 ? 93.780  136.868 140.671 1.00 90.55  ? 300 LEU B CA  1 
ATOM 3907 C C   . LEU B 2 305 ? 92.368  136.875 140.104 1.00 90.55  ? 300 LEU B C   1 
ATOM 3908 O O   . LEU B 2 305 ? 91.403  137.038 140.858 1.00 90.55  ? 300 LEU B O   1 
ATOM 3909 C CB  . LEU B 2 305 ? 94.284  138.294 140.875 1.00 90.55  ? 300 LEU B CB  1 
ATOM 3910 C CG  . LEU B 2 305 ? 95.759  138.374 141.250 1.00 90.55  ? 300 LEU B CG  1 
ATOM 3911 C CD1 . LEU B 2 305 ? 96.290  139.784 141.109 1.00 90.55  ? 300 LEU B CD1 1 
ATOM 3912 C CD2 . LEU B 2 305 ? 95.937  137.879 142.661 1.00 90.55  ? 300 LEU B CD2 1 
ATOM 3913 N N   . LYS B 2 306 ? 92.211  136.690 138.795 1.00 84.09  ? 301 LYS B N   1 
ATOM 3914 C CA  . LYS B 2 306 ? 90.896  136.777 138.182 1.00 84.09  ? 301 LYS B CA  1 
ATOM 3915 C C   . LYS B 2 306 ? 90.390  135.464 137.607 1.00 84.09  ? 301 LYS B C   1 
ATOM 3916 O O   . LYS B 2 306 ? 89.183  135.348 137.366 1.00 84.09  ? 301 LYS B O   1 
ATOM 3917 C CB  . LYS B 2 306 ? 90.887  137.844 137.075 1.00 84.09  ? 301 LYS B CB  1 
ATOM 3918 N N   . ALA B 2 307 ? 91.262  134.485 137.378 1.00 82.08  ? 302 ALA B N   1 
ATOM 3919 C CA  . ALA B 2 307 ? 90.868  133.176 136.853 1.00 82.08  ? 302 ALA B CA  1 
ATOM 3920 C C   . ALA B 2 307 ? 90.157  133.297 135.508 1.00 82.08  ? 302 ALA B C   1 
ATOM 3921 O O   . ALA B 2 307 ? 88.992  132.923 135.363 1.00 82.08  ? 302 ALA B O   1 
ATOM 3922 C CB  . ALA B 2 307 ? 90.004  132.412 137.857 1.00 82.08  ? 302 ALA B CB  1 
ATOM 3923 N N   . ASP B 2 308 ? 90.864  133.831 134.518 1.00 80.43  ? 303 ASP B N   1 
ATOM 3924 C CA  . ASP B 2 308 ? 90.404  133.857 133.137 1.00 80.43  ? 303 ASP B CA  1 
ATOM 3925 C C   . ASP B 2 308 ? 91.597  133.602 132.233 1.00 80.43  ? 303 ASP B C   1 
ATOM 3926 O O   . ASP B 2 308 ? 92.626  134.272 132.361 1.00 80.43  ? 303 ASP B O   1 
ATOM 3927 C CB  . ASP B 2 308 ? 89.748  135.197 132.792 1.00 80.43  ? 303 ASP B CB  1 
ATOM 3928 N N   . ARG B 2 309 ? 91.465  132.635 131.330 1.00 82.24  ? 304 ARG B N   1 
ATOM 3929 C CA  . ARG B 2 309 ? 92.578  132.271 130.463 1.00 82.24  ? 304 ARG B CA  1 
ATOM 3930 C C   . ARG B 2 309 ? 92.964  133.445 129.573 1.00 82.24  ? 304 ARG B C   1 
ATOM 3931 O O   . ARG B 2 309 ? 92.109  134.206 129.116 1.00 82.24  ? 304 ARG B O   1 
ATOM 3932 C CB  . ARG B 2 309 ? 92.213  131.055 129.613 1.00 82.24  ? 304 ARG B CB  1 
ATOM 3933 C CG  . ARG B 2 309 ? 93.403  130.390 128.957 1.00 82.24  ? 304 ARG B CG  1 
ATOM 3934 C CD  . ARG B 2 309 ? 93.039  129.026 128.399 1.00 82.24  ? 304 ARG B CD  1 
ATOM 3935 N NE  . ARG B 2 309 ? 92.896  129.043 126.949 1.00 82.24  ? 304 ARG B NE  1 
ATOM 3936 C CZ  . ARG B 2 309 ? 91.845  128.560 126.299 1.00 82.24  ? 304 ARG B CZ  1 
ATOM 3937 N NH1 . ARG B 2 309 ? 90.838  128.021 126.972 1.00 82.24  ? 304 ARG B NH1 1 
ATOM 3938 N NH2 . ARG B 2 309 ? 91.799  128.618 124.977 1.00 82.24  ? 304 ARG B NH2 1 
ATOM 3939 N N   . ALA B 2 310 ? 94.263  133.595 129.337 1.00 81.20  ? 305 ALA B N   1 
ATOM 3940 C CA  . ALA B 2 310 ? 94.784  134.764 128.642 1.00 81.20  ? 305 ALA B CA  1 
ATOM 3941 C C   . ALA B 2 310 ? 95.665  134.436 127.450 1.00 81.20  ? 305 ALA B C   1 
ATOM 3942 O O   . ALA B 2 310 ? 95.626  135.157 126.451 1.00 81.20  ? 305 ALA B O   1 
ATOM 3943 C CB  . ALA B 2 310 ? 95.572  135.647 129.617 1.00 81.20  ? 305 ALA B CB  1 
ATOM 3944 N N   . GLY B 2 311 ? 96.462  133.372 127.517 1.00 80.93  ? 306 GLY B N   1 
ATOM 3945 C CA  . GLY B 2 311 ? 97.406  133.084 126.458 1.00 80.93  ? 306 GLY B CA  1 
ATOM 3946 C C   . GLY B 2 311 ? 97.550  131.595 126.222 1.00 80.93  ? 306 GLY B C   1 
ATOM 3947 O O   . GLY B 2 311 ? 97.200  130.767 127.066 1.00 80.93  ? 306 GLY B O   1 
ATOM 3948 N N   . VAL B 2 312 ? 98.079  131.271 125.045 1.00 77.74  ? 307 VAL B N   1 
ATOM 3949 C CA  . VAL B 2 312 ? 98.308  129.894 124.630 1.00 77.74  ? 307 VAL B CA  1 
ATOM 3950 C C   . VAL B 2 312 ? 99.661  129.822 123.941 1.00 77.74  ? 307 VAL B C   1 
ATOM 3951 O O   . VAL B 2 312 ? 100.007 130.676 123.119 1.00 77.74  ? 307 VAL B O   1 
ATOM 3952 C CB  . VAL B 2 312 ? 97.190  129.380 123.694 1.00 77.74  ? 307 VAL B CB  1 
ATOM 3953 C CG1 . VAL B 2 312 ? 97.580  128.054 123.065 1.00 77.74  ? 307 VAL B CG1 1 
ATOM 3954 C CG2 . VAL B 2 312 ? 95.878  129.245 124.451 1.00 77.74  ? 307 VAL B CG2 1 
ATOM 3955 N N   . LEU B 2 313 ? 100.431 128.793 124.280 1.00 76.36  ? 308 LEU B N   1 
ATOM 3956 C CA  . LEU B 2 313 ? 101.757 128.579 123.710 1.00 76.36  ? 308 LEU B CA  1 
ATOM 3957 C C   . LEU B 2 313 ? 101.782 127.180 123.113 1.00 76.36  ? 308 LEU B C   1 
ATOM 3958 O O   . LEU B 2 313 ? 101.875 126.193 123.848 1.00 76.36  ? 308 LEU B O   1 
ATOM 3959 C CB  . LEU B 2 313 ? 102.842 128.728 124.772 1.00 76.36  ? 308 LEU B CB  1 
ATOM 3960 C CG  . LEU B 2 313 ? 103.034 130.110 125.392 1.00 76.36  ? 308 LEU B CG  1 
ATOM 3961 C CD1 . LEU B 2 313 ? 104.051 130.030 126.514 1.00 76.36  ? 308 LEU B CD1 1 
ATOM 3962 C CD2 . LEU B 2 313 ? 103.448 131.135 124.347 1.00 76.36  ? 308 LEU B CD2 1 
ATOM 3963 N N   . ALA B 2 314 ? 101.699 127.089 121.788 1.00 76.45  ? 309 ALA B N   1 
ATOM 3964 C CA  . ALA B 2 314 ? 101.630 125.804 121.100 1.00 76.45  ? 309 ALA B CA  1 
ATOM 3965 C C   . ALA B 2 314 ? 102.680 125.779 120.001 1.00 76.45  ? 309 ALA B C   1 
ATOM 3966 O O   . ALA B 2 314 ? 102.535 126.463 118.983 1.00 76.45  ? 309 ALA B O   1 
ATOM 3967 C CB  . ALA B 2 314 ? 100.234 125.560 120.526 1.00 76.45  ? 309 ALA B CB  1 
ATOM 3968 N N   . GLY B 2 315 ? 103.734 124.998 120.207 1.00 78.65  ? 310 GLY B N   1 
ATOM 3969 C CA  . GLY B 2 315 ? 104.753 124.829 119.192 1.00 78.65  ? 310 GLY B CA  1 
ATOM 3970 C C   . GLY B 2 315 ? 105.349 123.439 119.183 1.00 78.65  ? 310 GLY B C   1 
ATOM 3971 O O   . GLY B 2 315 ? 106.334 123.182 118.485 1.00 78.65  ? 310 GLY B O   1 
ATOM 3972 N N   . HIS B 2 316 ? 104.757 122.530 119.948 1.00 78.22  ? 311 HIS B N   1 
ATOM 3973 C CA  . HIS B 2 316 ? 105.327 121.215 120.181 1.00 78.22  ? 311 HIS B CA  1 
ATOM 3974 C C   . HIS B 2 316 ? 104.516 120.140 119.473 1.00 78.22  ? 311 HIS B C   1 
ATOM 3975 O O   . HIS B 2 316 ? 103.334 120.324 119.173 1.00 78.22  ? 311 HIS B O   1 
ATOM 3976 C CB  . HIS B 2 316 ? 105.392 120.911 121.678 1.00 78.22  ? 311 HIS B CB  1 
ATOM 3977 C CG  . HIS B 2 316 ? 106.603 121.472 122.353 1.00 78.22  ? 311 HIS B CG  1 
ATOM 3978 N ND1 . HIS B 2 316 ? 107.878 121.033 122.077 1.00 78.22  ? 311 HIS B ND1 1 
ATOM 3979 C CD2 . HIS B 2 316 ? 106.733 122.442 123.289 1.00 78.22  ? 311 HIS B CD2 1 
ATOM 3980 C CE1 . HIS B 2 316 ? 108.742 121.704 122.814 1.00 78.22  ? 311 HIS B CE1 1 
ATOM 3981 N NE2 . HIS B 2 316 ? 108.073 122.566 123.559 1.00 78.22  ? 311 HIS B NE2 1 
ATOM 3982 N N   . ASP B 2 317 ? 105.170 119.012 119.208 1.00 79.73  ? 312 ASP B N   1 
ATOM 3983 C CA  . ASP B 2 317 ? 104.546 117.881 118.537 1.00 79.73  ? 312 ASP B CA  1 
ATOM 3984 C C   . ASP B 2 317 ? 104.298 116.695 119.460 1.00 79.73  ? 312 ASP B C   1 
ATOM 3985 O O   . ASP B 2 317 ? 103.849 115.648 118.987 1.00 79.73  ? 312 ASP B O   1 
ATOM 3986 C CB  . ASP B 2 317 ? 105.407 117.437 117.351 1.00 79.73  ? 312 ASP B CB  1 
ATOM 3987 N N   . ASN B 2 318 ? 104.575 116.826 120.751 1.00 77.35  ? 313 ASN B N   1 
ATOM 3988 C CA  . ASN B 2 318 ? 104.372 115.729 121.693 1.00 77.35  ? 313 ASN B CA  1 
ATOM 3989 C C   . ASN B 2 318 ? 104.020 116.325 123.053 1.00 77.35  ? 313 ASN B C   1 
ATOM 3990 O O   . ASN B 2 318 ? 103.678 117.506 123.157 1.00 77.35  ? 313 ASN B O   1 
ATOM 3991 C CB  . ASN B 2 318 ? 105.607 114.814 121.735 1.00 77.35  ? 313 ASN B CB  1 
ATOM 3992 C CG  . ASN B 2 318 ? 105.239 113.346 121.760 1.00 77.35  ? 313 ASN B CG  1 
ATOM 3993 O OD1 . ASN B 2 318 ? 104.151 112.977 122.199 1.00 77.35  ? 313 ASN B OD1 1 
ATOM 3994 N ND2 . ASN B 2 318 ? 106.144 112.499 121.290 1.00 77.35  ? 313 ASN B ND2 1 
ATOM 3995 N N   . ARG B 2 319 ? 104.103 115.505 124.095 1.00 74.68  ? 314 ARG B N   1 
ATOM 3996 C CA  . ARG B 2 319 ? 103.702 115.914 125.433 1.00 74.68  ? 314 ARG B CA  1 
ATOM 3997 C C   . ARG B 2 319 ? 104.747 116.817 126.072 1.00 74.68  ? 314 ARG B C   1 
ATOM 3998 O O   . ARG B 2 319 ? 105.950 116.583 125.947 1.00 74.68  ? 314 ARG B O   1 
ATOM 3999 C CB  . ARG B 2 319 ? 103.491 114.683 126.312 1.00 74.68  ? 314 ARG B CB  1 
ATOM 4000 C CG  . ARG B 2 319 ? 102.596 114.900 127.509 1.00 74.68  ? 314 ARG B CG  1 
ATOM 4001 C CD  . ARG B 2 319 ? 102.274 113.572 128.164 1.00 74.68  ? 314 ARG B CD  1 
ATOM 4002 N NE  . ARG B 2 319 ? 103.240 113.215 129.199 1.00 74.68  ? 314 ARG B NE  1 
ATOM 4003 C CZ  . ARG B 2 319 ? 103.030 113.365 130.502 1.00 74.68  ? 314 ARG B CZ  1 
ATOM 4004 N NH1 . ARG B 2 319 ? 101.881 113.861 130.938 1.00 74.68  ? 314 ARG B NH1 1 
ATOM 4005 N NH2 . ARG B 2 319 ? 103.966 113.014 131.370 1.00 74.68  ? 314 ARG B NH2 1 
ATOM 4006 N N   . VAL B 2 320 ? 104.278 117.832 126.781 1.00 70.48  ? 315 VAL B N   1 
ATOM 4007 C CA  . VAL B 2 320 ? 105.135 118.727 127.549 1.00 70.48  ? 315 VAL B CA  1 
ATOM 4008 C C   . VAL B 2 320 ? 105.438 118.071 128.888 1.00 70.48  ? 315 VAL B C   1 
ATOM 4009 O O   . VAL B 2 320 ? 104.570 117.423 129.483 1.00 70.48  ? 315 VAL B O   1 
ATOM 4010 C CB  . VAL B 2 320 ? 104.462 120.100 127.730 1.00 70.48  ? 315 VAL B CB  1 
ATOM 4011 C CG1 . VAL B 2 320 ? 105.092 120.869 128.873 1.00 70.48  ? 315 VAL B CG1 1 
ATOM 4012 C CG2 . VAL B 2 320 ? 104.550 120.899 126.446 1.00 70.48  ? 315 VAL B CG2 1 
ATOM 4013 N N   . SER B 2 321 ? 106.676 118.212 129.355 1.00 70.30  ? 316 SER B N   1 
ATOM 4014 C CA  . SER B 2 321 ? 107.112 117.549 130.576 1.00 70.30  ? 316 SER B CA  1 
ATOM 4015 C C   . SER B 2 321 ? 107.729 118.476 131.609 1.00 70.30  ? 316 SER B C   1 
ATOM 4016 O O   . SER B 2 321 ? 107.617 118.194 132.803 1.00 70.30  ? 316 SER B O   1 
ATOM 4017 C CB  . SER B 2 321 ? 108.125 116.444 130.247 1.00 70.30  ? 316 SER B CB  1 
ATOM 4018 O OG  . SER B 2 321 ? 109.156 116.931 129.406 1.00 70.30  ? 316 SER B OG  1 
ATOM 4019 N N   . CYS B 2 322 ? 108.373 119.565 131.199 1.00 69.03  ? 317 CYS B N   1 
ATOM 4020 C CA  . CYS B 2 322 ? 109.044 120.459 132.130 1.00 69.03  ? 317 CYS B CA  1 
ATOM 4021 C C   . CYS B 2 322 ? 108.678 121.903 131.818 1.00 69.03  ? 317 CYS B C   1 
ATOM 4022 O O   . CYS B 2 322 ? 108.115 122.216 130.767 1.00 69.03  ? 317 CYS B O   1 
ATOM 4023 C CB  . CYS B 2 322 ? 110.564 120.268 132.082 1.00 69.03  ? 317 CYS B CB  1 
ATOM 4024 S SG  . CYS B 2 322 ? 111.317 120.706 130.504 1.00 69.03  ? 317 CYS B SG  1 
ATOM 4025 N N   . LEU B 2 323 ? 109.009 122.788 132.754 1.00 66.58  ? 318 LEU B N   1 
ATOM 4026 C CA  . LEU B 2 323 ? 108.721 124.207 132.612 1.00 66.58  ? 318 LEU B CA  1 
ATOM 4027 C C   . LEU B 2 323 ? 109.563 124.966 133.627 1.00 66.58  ? 318 LEU B C   1 
ATOM 4028 O O   . LEU B 2 323 ? 109.899 124.436 134.687 1.00 66.58  ? 318 LEU B O   1 
ATOM 4029 C CB  . LEU B 2 323 ? 107.229 124.488 132.813 1.00 66.58  ? 318 LEU B CB  1 
ATOM 4030 C CG  . LEU B 2 323 ? 106.680 125.887 132.554 1.00 66.58  ? 318 LEU B CG  1 
ATOM 4031 C CD1 . LEU B 2 323 ? 106.799 126.225 131.092 1.00 66.58  ? 318 LEU B CD1 1 
ATOM 4032 C CD2 . LEU B 2 323 ? 105.237 125.971 133.001 1.00 66.58  ? 318 LEU B CD2 1 
ATOM 4033 N N   . GLY B 2 324 ? 109.904 126.209 133.294 1.00 66.52  ? 319 GLY B N   1 
ATOM 4034 C CA  . GLY B 2 324 ? 110.756 126.998 134.163 1.00 66.52  ? 319 GLY B CA  1 
ATOM 4035 C C   . GLY B 2 324 ? 110.808 128.478 133.839 1.00 66.52  ? 319 GLY B C   1 
ATOM 4036 O O   . GLY B 2 324 ? 110.697 128.873 132.675 1.00 66.52  ? 319 GLY B O   1 
ATOM 4037 N N   . VAL B 2 325 ? 110.979 129.304 134.867 1.00 67.14  ? 320 VAL B N   1 
ATOM 4038 C CA  . VAL B 2 325 ? 111.025 130.753 134.737 1.00 67.14  ? 320 VAL B CA  1 
ATOM 4039 C C   . VAL B 2 325 ? 112.292 131.254 135.413 1.00 67.14  ? 320 VAL B C   1 
ATOM 4040 O O   . VAL B 2 325 ? 112.624 130.823 136.521 1.00 67.14  ? 320 VAL B O   1 
ATOM 4041 C CB  . VAL B 2 325 ? 109.778 131.418 135.350 1.00 67.14  ? 320 VAL B CB  1 
ATOM 4042 C CG1 . VAL B 2 325 ? 109.892 132.924 135.282 1.00 67.14  ? 320 VAL B CG1 1 
ATOM 4043 C CG2 . VAL B 2 325 ? 108.533 130.951 134.633 1.00 67.14  ? 320 VAL B CG2 1 
ATOM 4044 N N   . THR B 2 326 ? 112.993 132.167 134.749 1.00 73.41  ? 321 THR B N   1 
ATOM 4045 C CA  . THR B 2 326 ? 114.285 132.622 135.231 1.00 73.41  ? 321 THR B CA  1 
ATOM 4046 C C   . THR B 2 326 ? 114.125 133.602 136.388 1.00 73.41  ? 321 THR B C   1 
ATOM 4047 O O   . THR B 2 326 ? 113.049 134.154 136.629 1.00 73.41  ? 321 THR B O   1 
ATOM 4048 C CB  . THR B 2 326 ? 115.079 133.277 134.106 1.00 73.41  ? 321 THR B CB  1 
ATOM 4049 O OG1 . THR B 2 326 ? 116.339 133.725 134.615 1.00 73.41  ? 321 THR B OG1 1 
ATOM 4050 C CG2 . THR B 2 326 ? 114.318 134.459 133.538 1.00 73.41  ? 321 THR B CG2 1 
ATOM 4051 N N   . ASP B 2 327 ? 115.226 133.810 137.114 1.00 77.75  ? 322 ASP B N   1 
ATOM 4052 C CA  . ASP B 2 327 ? 115.190 134.699 138.267 1.00 77.75  ? 322 ASP B CA  1 
ATOM 4053 C C   . ASP B 2 327 ? 115.096 136.158 137.848 1.00 77.75  ? 322 ASP B C   1 
ATOM 4054 O O   . ASP B 2 327 ? 114.499 136.970 138.563 1.00 77.75  ? 322 ASP B O   1 
ATOM 4055 C CB  . ASP B 2 327 ? 116.423 134.483 139.142 1.00 77.75  ? 322 ASP B CB  1 
ATOM 4056 C CG  . ASP B 2 327 ? 116.398 133.151 139.857 1.00 77.75  ? 322 ASP B CG  1 
ATOM 4057 O OD1 . ASP B 2 327 ? 115.292 132.647 140.139 1.00 77.75  ? 322 ASP B OD1 1 
ATOM 4058 O OD2 . ASP B 2 327 ? 117.486 132.606 140.139 1.00 77.75  ? 322 ASP B OD2 1 
ATOM 4059 N N   . ASP B 2 328 ? 115.682 136.510 136.704 1.00 80.75  ? 323 ASP B N   1 
ATOM 4060 C CA  . ASP B 2 328 ? 115.537 137.868 136.195 1.00 80.75  ? 323 ASP B CA  1 
ATOM 4061 C C   . ASP B 2 328 ? 114.094 138.176 135.829 1.00 80.75  ? 323 ASP B C   1 
ATOM 4062 O O   . ASP B 2 328 ? 113.622 139.294 136.058 1.00 80.75  ? 323 ASP B O   1 
ATOM 4063 C CB  . ASP B 2 328 ? 116.445 138.076 134.984 1.00 80.75  ? 323 ASP B CB  1 
ATOM 4064 C CG  . ASP B 2 328 ? 117.853 138.474 135.372 1.00 80.75  ? 323 ASP B CG  1 
ATOM 4065 O OD1 . ASP B 2 328 ? 118.154 138.505 136.583 1.00 80.75  ? 323 ASP B OD1 1 
ATOM 4066 O OD2 . ASP B 2 328 ? 118.662 138.761 134.464 1.00 80.75  ? 323 ASP B OD2 1 
ATOM 4067 N N   . GLY B 2 329 ? 113.381 137.204 135.271 1.00 79.36  ? 324 GLY B N   1 
ATOM 4068 C CA  . GLY B 2 329 ? 112.019 137.402 134.832 1.00 79.36  ? 324 GLY B CA  1 
ATOM 4069 C C   . GLY B 2 329 ? 111.858 137.649 133.354 1.00 79.36  ? 324 GLY B C   1 
ATOM 4070 O O   . GLY B 2 329 ? 110.761 138.018 132.924 1.00 79.36  ? 324 GLY B O   1 
ATOM 4071 N N   . MET B 2 330 ? 112.904 137.443 132.562 1.00 80.13  ? 325 MET B N   1 
ATOM 4072 C CA  . MET B 2 330 ? 112.936 137.887 131.179 1.00 80.13  ? 325 MET B CA  1 
ATOM 4073 C C   . MET B 2 330 ? 112.893 136.722 130.193 1.00 80.13  ? 325 MET B C   1 
ATOM 4074 O O   . MET B 2 330 ? 113.023 136.934 128.984 1.00 80.13  ? 325 MET B O   1 
ATOM 4075 C CB  . MET B 2 330 ? 114.179 138.762 130.973 1.00 80.13  ? 325 MET B CB  1 
ATOM 4076 C CG  . MET B 2 330 ? 114.334 139.436 129.625 1.00 80.13  ? 325 MET B CG  1 
ATOM 4077 S SD  . MET B 2 330 ? 115.830 140.432 129.558 1.00 80.13  ? 325 MET B SD  1 
ATOM 4078 C CE  . MET B 2 330 ? 115.366 141.793 130.625 1.00 80.13  ? 325 MET B CE  1 
ATOM 4079 N N   . ALA B 2 331 ? 112.672 135.502 130.671 1.00 71.56  ? 326 ALA B N   1 
ATOM 4080 C CA  . ALA B 2 331 ? 112.549 134.366 129.771 1.00 71.56  ? 326 ALA B CA  1 
ATOM 4081 C C   . ALA B 2 331 ? 111.721 133.281 130.439 1.00 71.56  ? 326 ALA B C   1 
ATOM 4082 O O   . ALA B 2 331 ? 111.600 133.230 131.666 1.00 71.56  ? 326 ALA B O   1 
ATOM 4083 C CB  . ALA B 2 331 ? 113.920 133.820 129.369 1.00 71.56  ? 326 ALA B CB  1 
ATOM 4084 N N   . VAL B 2 332 ? 111.152 132.412 129.608 1.00 68.16  ? 327 VAL B N   1 
ATOM 4085 C CA  . VAL B 2 332 ? 110.396 131.248 130.057 1.00 68.16  ? 327 VAL B CA  1 
ATOM 4086 C C   . VAL B 2 332 ? 110.736 130.089 129.134 1.00 68.16  ? 327 VAL B C   1 
ATOM 4087 O O   . VAL B 2 332 ? 110.698 130.237 127.908 1.00 68.16  ? 327 VAL B O   1 
ATOM 4088 C CB  . VAL B 2 332 ? 108.879 131.509 130.055 1.00 68.16  ? 327 VAL B CB  1 
ATOM 4089 C CG1 . VAL B 2 332 ? 108.118 130.199 130.086 1.00 68.16  ? 327 VAL B CG1 1 
ATOM 4090 C CG2 . VAL B 2 332 ? 108.488 132.379 131.232 1.00 68.16  ? 327 VAL B CG2 1 
ATOM 4091 N N   . ALA B 2 333 ? 111.063 128.939 129.712 1.00 65.58  ? 328 ALA B N   1 
ATOM 4092 C CA  . ALA B 2 333 ? 111.520 127.791 128.948 1.00 65.58  ? 328 ALA B CA  1 
ATOM 4093 C C   . ALA B 2 333 ? 110.568 126.618 129.116 1.00 65.58  ? 328 ALA B C   1 
ATOM 4094 O O   . ALA B 2 333 ? 109.947 126.445 130.168 1.00 65.58  ? 328 ALA B O   1 
ATOM 4095 C CB  . ALA B 2 333 ? 112.928 127.377 129.376 1.00 65.58  ? 328 ALA B CB  1 
ATOM 4096 N N   . THR B 2 334 ? 110.461 125.810 128.063 1.00 70.39  ? 329 THR B N   1 
ATOM 4097 C CA  . THR B 2 334 ? 109.613 124.628 128.066 1.00 70.39  ? 329 THR B CA  1 
ATOM 4098 C C   . THR B 2 334 ? 110.394 123.455 127.499 1.00 70.39  ? 329 THR B C   1 
ATOM 4099 O O   . THR B 2 334 ? 111.461 123.620 126.906 1.00 70.39  ? 329 THR B O   1 
ATOM 4100 C CB  . THR B 2 334 ? 108.331 124.816 127.244 1.00 70.39  ? 329 THR B CB  1 
ATOM 4101 O OG1 . THR B 2 334 ? 108.656 124.827 125.850 1.00 70.39  ? 329 THR B OG1 1 
ATOM 4102 C CG2 . THR B 2 334 ? 107.638 126.115 127.602 1.00 70.39  ? 329 THR B CG2 1 
ATOM 4103 N N   . GLY B 2 335 ? 109.846 122.262 127.688 1.00 72.05  ? 330 GLY B N   1 
ATOM 4104 C CA  . GLY B 2 335 ? 110.439 121.064 127.134 1.00 72.05  ? 330 GLY B CA  1 
ATOM 4105 C C   . GLY B 2 335 ? 109.423 119.963 126.925 1.00 72.05  ? 330 GLY B C   1 
ATOM 4106 O O   . GLY B 2 335 ? 108.526 119.774 127.751 1.00 72.05  ? 330 GLY B O   1 
ATOM 4107 N N   . SER B 2 336 ? 109.550 119.226 125.826 1.00 74.29  ? 331 SER B N   1 
ATOM 4108 C CA  . SER B 2 336 ? 108.580 118.212 125.449 1.00 74.29  ? 331 SER B CA  1 
ATOM 4109 C C   . SER B 2 336 ? 109.306 116.962 124.973 1.00 74.29  ? 331 SER B C   1 
ATOM 4110 O O   . SER B 2 336 ? 110.533 116.939 124.844 1.00 74.29  ? 331 SER B O   1 
ATOM 4111 C CB  . SER B 2 336 ? 107.627 118.737 124.368 1.00 74.29  ? 331 SER B CB  1 
ATOM 4112 O OG  . SER B 2 336 ? 106.797 117.701 123.874 1.00 74.29  ? 331 SER B OG  1 
ATOM 4113 N N   . TRP B 2 337 ? 108.533 115.916 124.695 1.00 73.35  ? 332 TRP B N   1 
ATOM 4114 C CA  . TRP B 2 337 ? 109.075 114.612 124.342 1.00 73.35  ? 332 TRP B CA  1 
ATOM 4115 C C   . TRP B 2 337 ? 109.531 114.531 122.891 1.00 73.35  ? 332 TRP B C   1 
ATOM 4116 O O   . TRP B 2 337 ? 109.743 113.425 122.383 1.00 73.35  ? 332 TRP B O   1 
ATOM 4117 C CB  . TRP B 2 337 ? 108.047 113.514 124.625 1.00 73.35  ? 332 TRP B CB  1 
ATOM 4118 C CG  . TRP B 2 337 ? 107.700 113.365 126.077 1.00 73.35  ? 332 TRP B CG  1 
ATOM 4119 C CD1 . TRP B 2 337 ? 108.099 114.170 127.102 1.00 73.35  ? 332 TRP B CD1 1 
ATOM 4120 C CD2 . TRP B 2 337 ? 106.879 112.349 126.665 1.00 73.35  ? 332 TRP B CD2 1 
ATOM 4121 N NE1 . TRP B 2 337 ? 107.578 113.721 128.288 1.00 73.35  ? 332 TRP B NE1 1 
ATOM 4122 C CE2 . TRP B 2 337 ? 106.825 112.604 128.046 1.00 73.35  ? 332 TRP B CE2 1 
ATOM 4123 C CE3 . TRP B 2 337 ? 106.183 111.251 126.156 1.00 73.35  ? 332 TRP B CE3 1 
ATOM 4124 C CZ2 . TRP B 2 337 ? 106.105 111.801 128.924 1.00 73.35  ? 332 TRP B CZ2 1 
ATOM 4125 C CZ3 . TRP B 2 337 ? 105.469 110.458 127.031 1.00 73.35  ? 332 TRP B CZ3 1 
ATOM 4126 C CH2 . TRP B 2 337 ? 105.436 110.736 128.397 1.00 73.35  ? 332 TRP B CH2 1 
ATOM 4127 N N   . ASP B 2 338 ? 109.684 115.664 122.215 1.00 76.03  ? 333 ASP B N   1 
ATOM 4128 C CA  . ASP B 2 338 ? 110.225 115.700 120.865 1.00 76.03  ? 333 ASP B CA  1 
ATOM 4129 C C   . ASP B 2 338 ? 111.705 116.058 120.840 1.00 76.03  ? 333 ASP B C   1 
ATOM 4130 O O   . ASP B 2 338 ? 112.245 116.327 119.762 1.00 76.03  ? 333 ASP B O   1 
ATOM 4131 C CB  . ASP B 2 338 ? 109.439 116.692 120.008 1.00 76.03  ? 333 ASP B CB  1 
ATOM 4132 C CG  . ASP B 2 338 ? 109.193 118.003 120.719 1.00 76.03  ? 333 ASP B CG  1 
ATOM 4133 O OD1 . ASP B 2 338 ? 109.563 118.109 121.906 1.00 76.03  ? 333 ASP B OD1 1 
ATOM 4134 O OD2 . ASP B 2 338 ? 108.631 118.925 120.093 1.00 76.03  ? 333 ASP B OD2 1 
ATOM 4135 N N   . SER B 2 339 ? 112.359 116.089 122.003 1.00 74.79  ? 334 SER B N   1 
ATOM 4136 C CA  . SER B 2 339 ? 113.790 116.362 122.126 1.00 74.79  ? 334 SER B CA  1 
ATOM 4137 C C   . SER B 2 339 ? 114.153 117.781 121.702 1.00 74.79  ? 334 SER B C   1 
ATOM 4138 O O   . SER B 2 339 ? 115.235 118.013 121.162 1.00 74.79  ? 334 SER B O   1 
ATOM 4139 C CB  . SER B 2 339 ? 114.625 115.345 121.341 1.00 74.79  ? 334 SER B CB  1 
ATOM 4140 O OG  . SER B 2 339 ? 114.581 115.614 119.951 1.00 74.79  ? 334 SER B OG  1 
ATOM 4141 N N   . PHE B 2 340 ? 113.263 118.740 121.943 1.00 74.16  ? 335 PHE B N   1 
ATOM 4142 C CA  . PHE B 2 340 ? 113.511 120.133 121.607 1.00 74.16  ? 335 PHE B CA  1 
ATOM 4143 C C   . PHE B 2 340 ? 113.276 121.017 122.820 1.00 74.16  ? 335 PHE B C   1 
ATOM 4144 O O   . PHE B 2 340 ? 112.297 120.839 123.550 1.00 74.16  ? 335 PHE B O   1 
ATOM 4145 C CB  . PHE B 2 340 ? 112.619 120.603 120.451 1.00 74.16  ? 335 PHE B CB  1 
ATOM 4146 C CG  . PHE B 2 340 ? 112.821 119.841 119.174 1.00 74.16  ? 335 PHE B CG  1 
ATOM 4147 C CD1 . PHE B 2 340 ? 114.092 119.579 118.701 1.00 74.16  ? 335 PHE B CD1 1 
ATOM 4148 C CD2 . PHE B 2 340 ? 111.737 119.400 118.440 1.00 74.16  ? 335 PHE B CD2 1 
ATOM 4149 C CE1 . PHE B 2 340 ? 114.279 118.882 117.529 1.00 74.16  ? 335 PHE B CE1 1 
ATOM 4150 C CE2 . PHE B 2 340 ? 111.918 118.703 117.266 1.00 74.16  ? 335 PHE B CE2 1 
ATOM 4151 C CZ  . PHE B 2 340 ? 113.192 118.445 116.810 1.00 74.16  ? 335 PHE B CZ  1 
ATOM 4152 N N   . LEU B 2 341 ? 114.176 121.970 123.027 1.00 73.81  ? 336 LEU B N   1 
ATOM 4153 C CA  . LEU B 2 341 ? 114.000 123.020 124.018 1.00 73.81  ? 336 LEU B CA  1 
ATOM 4154 C C   . LEU B 2 341 ? 113.610 124.299 123.292 1.00 73.81  ? 336 LEU B C   1 
ATOM 4155 O O   . LEU B 2 341 ? 114.219 124.648 122.275 1.00 73.81  ? 336 LEU B O   1 
ATOM 4156 C CB  . LEU B 2 341 ? 115.280 123.251 124.821 1.00 73.81  ? 336 LEU B CB  1 
ATOM 4157 C CG  . LEU B 2 341 ? 115.501 122.528 126.151 1.00 73.81  ? 336 LEU B CG  1 
ATOM 4158 C CD1 . LEU B 2 341 ? 114.653 123.123 127.265 1.00 73.81  ? 336 LEU B CD1 1 
ATOM 4159 C CD2 . LEU B 2 341 ? 115.265 121.045 126.007 1.00 73.81  ? 336 LEU B CD2 1 
ATOM 4160 N N   . LYS B 2 342 ? 112.600 124.993 123.805 1.00 73.76  ? 337 LYS B N   1 
ATOM 4161 C CA  . LYS B 2 342 ? 112.130 126.235 123.207 1.00 73.76  ? 337 LYS B CA  1 
ATOM 4162 C C   . LYS B 2 342 ? 112.153 127.334 124.258 1.00 73.76  ? 337 LYS B C   1 
ATOM 4163 O O   . LYS B 2 342 ? 111.393 127.282 125.230 1.00 73.76  ? 337 LYS B O   1 
ATOM 4164 C CB  . LYS B 2 342 ? 110.727 126.062 122.624 1.00 73.76  ? 337 LYS B CB  1 
ATOM 4165 C CG  . LYS B 2 342 ? 110.734 125.611 121.175 1.00 73.76  ? 337 LYS B CG  1 
ATOM 4166 C CD  . LYS B 2 342 ? 109.372 125.762 120.531 1.00 73.76  ? 337 LYS B CD  1 
ATOM 4167 C CE  . LYS B 2 342 ? 109.153 124.689 119.480 1.00 73.76  ? 337 LYS B CE  1 
ATOM 4168 N NZ  . LYS B 2 342 ? 110.371 124.484 118.652 1.00 73.76  ? 337 LYS B NZ  1 
ATOM 4169 N N   . ILE B 2 343 ? 113.018 128.324 124.057 1.00 71.65  ? 338 ILE B N   1 
ATOM 4170 C CA  . ILE B 2 343 ? 113.166 129.437 124.984 1.00 71.65  ? 338 ILE B CA  1 
ATOM 4171 C C   . ILE B 2 343 ? 112.190 130.523 124.542 1.00 71.65  ? 338 ILE B C   1 
ATOM 4172 O O   . ILE B 2 343 ? 112.511 131.357 123.697 1.00 71.65  ? 338 ILE B O   1 
ATOM 4173 C CB  . ILE B 2 343 ? 114.604 129.954 125.023 1.00 71.65  ? 338 ILE B CB  1 
ATOM 4174 C CG1 . ILE B 2 343 ? 115.561 128.840 125.440 1.00 71.65  ? 338 ILE B CG1 1 
ATOM 4175 C CG2 . ILE B 2 343 ? 114.722 131.114 125.990 1.00 71.65  ? 338 ILE B CG2 1 
ATOM 4176 C CD1 . ILE B 2 343 ? 115.289 128.284 126.814 1.00 71.65  ? 338 ILE B CD1 1 
ATOM 4177 N N   . TRP B 2 344 ? 110.989 130.506 125.109 1.00 74.96  ? 339 TRP B N   1 
ATOM 4178 C CA  . TRP B 2 344 ? 109.991 131.500 124.762 1.00 74.96  ? 339 TRP B CA  1 
ATOM 4179 C C   . TRP B 2 344 ? 110.350 132.850 125.368 1.00 74.96  ? 339 TRP B C   1 
ATOM 4180 O O   . TRP B 2 344 ? 111.135 132.949 126.313 1.00 74.96  ? 339 TRP B O   1 
ATOM 4181 C CB  . TRP B 2 344 ? 108.605 131.067 125.237 1.00 74.96  ? 339 TRP B CB  1 
ATOM 4182 C CG  . TRP B 2 344 ? 108.073 129.848 124.547 1.00 74.96  ? 339 TRP B CG  1 
ATOM 4183 C CD1 . TRP B 2 344 ? 108.349 128.550 124.853 1.00 74.96  ? 339 TRP B CD1 1 
ATOM 4184 C CD2 . TRP B 2 344 ? 107.176 129.813 123.432 1.00 74.96  ? 339 TRP B CD2 1 
ATOM 4185 N NE1 . TRP B 2 344 ? 107.678 127.708 124.002 1.00 74.96  ? 339 TRP B NE1 1 
ATOM 4186 C CE2 . TRP B 2 344 ? 106.952 128.460 123.118 1.00 74.96  ? 339 TRP B CE2 1 
ATOM 4187 C CE3 . TRP B 2 344 ? 106.544 130.795 122.667 1.00 74.96  ? 339 TRP B CE3 1 
ATOM 4188 C CZ2 . TRP B 2 344 ? 106.121 128.064 122.076 1.00 74.96  ? 339 TRP B CZ2 1 
ATOM 4189 C CZ3 . TRP B 2 344 ? 105.718 130.401 121.631 1.00 74.96  ? 339 TRP B CZ3 1 
ATOM 4190 C CH2 . TRP B 2 344 ? 105.515 129.047 121.345 1.00 74.96  ? 339 TRP B CH2 1 
ATOM 4191 N N   . ASN B 2 345 ? 109.761 133.903 124.807 1.00 78.43  ? 340 ASN B N   1 
ATOM 4192 C CA  . ASN B 2 345 ? 110.005 135.263 125.271 1.00 78.43  ? 340 ASN B CA  1 
ATOM 4193 C C   . ASN B 2 345 ? 108.929 136.204 124.743 1.00 78.43  ? 340 ASN B C   1 
ATOM 4194 O O   . ASN B 2 345 ? 108.485 137.113 125.442 1.00 78.43  ? 340 ASN B O   1 
ATOM 4195 C CB  . ASN B 2 345 ? 111.387 135.744 124.830 1.00 78.43  ? 340 ASN B CB  1 
ATOM 4196 C CG  . ASN B 2 345 ? 111.784 137.058 125.470 1.00 78.43  ? 340 ASN B CG  1 
ATOM 4197 O OD1 . ASN B 2 345 ? 111.027 137.642 126.241 1.00 78.43  ? 340 ASN B OD1 1 
ATOM 4198 N ND2 . ASN B 2 345 ? 112.980 137.531 125.148 1.00 78.43  ? 340 ASN B ND2 1 
ATOM 4199 N N   . GLN C 3 11  ? 99.899  102.560 167.303 1.00 125.88 ? 11  GLN G N   1 
ATOM 4200 C CA  . GLN C 3 11  ? 100.092 102.634 165.860 1.00 127.99 ? 11  GLN G CA  1 
ATOM 4201 C C   . GLN C 3 11  ? 99.430  103.880 165.283 1.00 129.93 ? 11  GLN G C   1 
ATOM 4202 O O   . GLN C 3 11  ? 100.080 104.695 164.628 1.00 129.27 ? 11  GLN G O   1 
ATOM 4203 C CB  . GLN C 3 11  ? 99.539  101.380 165.181 1.00 127.55 ? 11  GLN G CB  1 
ATOM 4204 N N   . ALA C 3 12  ? 98.128  104.023 165.533 1.00 136.98 ? 12  ALA G N   1 
ATOM 4205 C CA  . ALA C 3 12  ? 97.382  105.169 165.031 1.00 137.05 ? 12  ALA G CA  1 
ATOM 4206 C C   . ALA C 3 12  ? 97.532  106.402 165.911 1.00 135.57 ? 12  ALA G C   1 
ATOM 4207 O O   . ALA C 3 12  ? 96.990  107.456 165.563 1.00 135.78 ? 12  ALA G O   1 
ATOM 4208 C CB  . ALA C 3 12  ? 95.901  104.813 164.892 1.00 136.20 ? 12  ALA G CB  1 
ATOM 4209 N N   . ARG C 3 13  ? 98.241  106.295 167.037 1.00 133.22 ? 13  ARG G N   1 
ATOM 4210 C CA  . ARG C 3 13  ? 98.411  107.445 167.919 1.00 134.29 ? 13  ARG G CA  1 
ATOM 4211 C C   . ARG C 3 13  ? 99.176  108.566 167.227 1.00 135.93 ? 13  ARG G C   1 
ATOM 4212 O O   . ARG C 3 13  ? 98.953  109.748 167.513 1.00 135.13 ? 13  ARG G O   1 
ATOM 4213 C CB  . ARG C 3 13  ? 99.124  107.021 169.202 1.00 135.12 ? 13  ARG G CB  1 
ATOM 4214 N N   . LYS C 3 14  ? 100.089 108.215 166.318 1.00 139.44 ? 14  LYS G N   1 
ATOM 4215 C CA  . LYS C 3 14  ? 100.843 109.237 165.601 1.00 139.27 ? 14  LYS G CA  1 
ATOM 4216 C C   . LYS C 3 14  ? 99.927  110.102 164.744 1.00 139.24 ? 14  LYS G C   1 
ATOM 4217 O O   . LYS C 3 14  ? 100.078 111.329 164.704 1.00 139.72 ? 14  LYS G O   1 
ATOM 4218 C CB  . LYS C 3 14  ? 101.924 108.584 164.740 1.00 136.86 ? 14  LYS G CB  1 
ATOM 4219 N N   . LEU C 3 15  ? 98.966  109.481 164.055 1.00 133.35 ? 15  LEU G N   1 
ATOM 4220 C CA  . LEU C 3 15  ? 98.067  110.241 163.193 1.00 132.05 ? 15  LEU G CA  1 
ATOM 4221 C C   . LEU C 3 15  ? 97.193  111.192 164.001 1.00 132.36 ? 15  LEU G C   1 
ATOM 4222 O O   . LEU C 3 15  ? 97.035  112.365 163.636 1.00 133.32 ? 15  LEU G O   1 
ATOM 4223 C CB  . LEU C 3 15  ? 97.203  109.288 162.368 1.00 130.64 ? 15  LEU G CB  1 
ATOM 4224 N N   . VAL C 3 16  ? 96.616  110.709 165.103 1.00 131.57 ? 16  VAL G N   1 
ATOM 4225 C CA  . VAL C 3 16  ? 95.769  111.577 165.914 1.00 132.43 ? 16  VAL G CA  1 
ATOM 4226 C C   . VAL C 3 16  ? 96.598  112.671 166.573 1.00 131.39 ? 16  VAL G C   1 
ATOM 4227 O O   . VAL C 3 16  ? 96.128  113.804 166.725 1.00 132.04 ? 16  VAL G O   1 
ATOM 4228 C CB  . VAL C 3 16  ? 94.964  110.756 166.943 1.00 133.35 ? 16  VAL G CB  1 
ATOM 4229 C CG1 . VAL C 3 16  ? 94.154  109.677 166.239 1.00 132.50 ? 16  VAL G CG1 1 
ATOM 4230 C CG2 . VAL C 3 16  ? 95.869  110.141 167.997 1.00 131.30 ? 16  VAL G CG2 1 
ATOM 4231 N N   . GLU C 3 17  ? 97.840  112.370 166.962 1.00 124.29 ? 17  GLU G N   1 
ATOM 4232 C CA  . GLU C 3 17  ? 98.707  113.404 167.517 1.00 125.21 ? 17  GLU G CA  1 
ATOM 4233 C C   . GLU C 3 17  ? 99.015  114.478 166.481 1.00 126.53 ? 17  GLU G C   1 
ATOM 4234 O O   . GLU C 3 17  ? 99.008  115.674 166.797 1.00 128.66 ? 17  GLU G O   1 
ATOM 4235 C CB  . GLU C 3 17  ? 99.997  112.779 168.046 1.00 124.27 ? 17  GLU G CB  1 
ATOM 4236 N N   . GLN C 3 18  ? 99.284  114.070 165.237 1.00 117.96 ? 18  GLN G N   1 
ATOM 4237 C CA  . GLN C 3 18  ? 99.525  115.040 164.174 1.00 116.46 ? 18  GLN G CA  1 
ATOM 4238 C C   . GLN C 3 18  ? 98.298  115.905 163.929 1.00 115.65 ? 18  GLN G C   1 
ATOM 4239 O O   . GLN C 3 18  ? 98.412  117.126 163.762 1.00 116.87 ? 18  GLN G O   1 
ATOM 4240 C CB  . GLN C 3 18  ? 99.931  114.319 162.889 1.00 116.78 ? 18  GLN G CB  1 
ATOM 4241 C CG  . GLN C 3 18  ? 100.107 115.237 161.694 1.00 116.48 ? 18  GLN G CG  1 
ATOM 4242 C CD  . GLN C 3 18  ? 101.243 116.220 161.877 1.00 118.33 ? 18  GLN G CD  1 
ATOM 4243 O OE1 . GLN C 3 18  ? 102.311 115.867 162.377 1.00 118.01 ? 18  GLN G OE1 1 
ATOM 4244 N NE2 . GLN C 3 18  ? 101.018 117.464 161.471 1.00 116.77 ? 18  GLN G NE2 1 
ATOM 4245 N N   . LEU C 3 19  ? 97.116  115.289 163.899 1.00 118.92 ? 19  LEU G N   1 
ATOM 4246 C CA  . LEU C 3 19  ? 95.896  116.060 163.680 1.00 120.49 ? 19  LEU G CA  1 
ATOM 4247 C C   . LEU C 3 19  ? 95.645  117.031 164.826 1.00 120.16 ? 19  LEU G C   1 
ATOM 4248 O O   . LEU C 3 19  ? 95.220  118.170 164.601 1.00 121.34 ? 19  LEU G O   1 
ATOM 4249 C CB  . LEU C 3 19  ? 94.705  115.122 163.487 1.00 120.75 ? 19  LEU G CB  1 
ATOM 4250 C CG  . LEU C 3 19  ? 94.329  114.789 162.041 1.00 120.53 ? 19  LEU G CG  1 
ATOM 4251 C CD1 . LEU C 3 19  ? 95.374  113.901 161.382 1.00 120.82 ? 19  LEU G CD1 1 
ATOM 4252 C CD2 . LEU C 3 19  ? 92.955  114.137 161.982 1.00 120.40 ? 19  LEU G CD2 1 
ATOM 4253 N N   . LYS C 3 20  ? 95.906  116.604 166.063 1.00 117.74 ? 20  LYS G N   1 
ATOM 4254 C CA  . LYS C 3 20  ? 95.741  117.499 167.203 1.00 116.79 ? 20  LYS G CA  1 
ATOM 4255 C C   . LYS C 3 20  ? 96.719  118.663 167.135 1.00 114.34 ? 20  LYS G C   1 
ATOM 4256 O O   . LYS C 3 20  ? 96.352  119.809 167.415 1.00 115.26 ? 20  LYS G O   1 
ATOM 4257 C CB  . LYS C 3 20  ? 95.917  116.723 168.509 1.00 117.35 ? 20  LYS G CB  1 
ATOM 4258 N N   . MET C 3 21  ? 97.973  118.386 166.769 1.00 115.84 ? 21  MET G N   1 
ATOM 4259 C CA  . MET C 3 21  ? 98.962  119.453 166.659 1.00 117.68 ? 21  MET G CA  1 
ATOM 4260 C C   . MET C 3 21  ? 98.580  120.450 165.573 1.00 118.78 ? 21  MET G C   1 
ATOM 4261 O O   . MET C 3 21  ? 98.704  121.665 165.764 1.00 118.63 ? 21  MET G O   1 
ATOM 4262 C CB  . MET C 3 21  ? 100.343 118.860 166.385 1.00 117.09 ? 21  MET G CB  1 
ATOM 4263 N N   . GLU C 3 22  ? 98.111  119.957 164.426 1.00 115.49 ? 22  GLU G N   1 
ATOM 4264 C CA  . GLU C 3 22  ? 97.743  120.845 163.330 1.00 113.53 ? 22  GLU G CA  1 
ATOM 4265 C C   . GLU C 3 22  ? 96.396  121.521 163.542 1.00 114.30 ? 22  GLU G C   1 
ATOM 4266 O O   . GLU C 3 22  ? 96.086  122.484 162.834 1.00 112.47 ? 22  GLU G O   1 
ATOM 4267 C CB  . GLU C 3 22  ? 97.724  120.073 162.010 1.00 111.16 ? 22  GLU G CB  1 
ATOM 4268 N N   . ALA C 3 23  ? 95.589  121.041 164.491 1.00 115.87 ? 23  ALA G N   1 
ATOM 4269 C CA  . ALA C 3 23  ? 94.273  121.632 164.702 1.00 113.45 ? 23  ALA G CA  1 
ATOM 4270 C C   . ALA C 3 23  ? 94.375  123.007 165.349 1.00 112.56 ? 23  ALA G C   1 
ATOM 4271 O O   . ALA C 3 23  ? 93.683  123.945 164.939 1.00 111.88 ? 23  ALA G O   1 
ATOM 4272 C CB  . ALA C 3 23  ? 93.409  120.702 165.552 1.00 113.56 ? 23  ALA G CB  1 
ATOM 4273 N N   . ASN C 3 24  ? 95.232  123.148 166.359 1.00 108.91 ? 24  ASN G N   1 
ATOM 4274 C CA  . ASN C 3 24  ? 95.372  124.408 167.088 1.00 108.79 ? 24  ASN G CA  1 
ATOM 4275 C C   . ASN C 3 24  ? 96.457  125.236 166.415 1.00 112.03 ? 24  ASN G C   1 
ATOM 4276 O O   . ASN C 3 24  ? 97.648  125.088 166.692 1.00 113.34 ? 24  ASN G O   1 
ATOM 4277 C CB  . ASN C 3 24  ? 95.688  124.148 168.555 1.00 106.20 ? 24  ASN G CB  1 
ATOM 4278 N N   . ILE C 3 25  ? 96.038  126.122 165.513 1.00 100.97 ? 25  ILE G N   1 
ATOM 4279 C CA  . ILE C 3 25  ? 96.935  127.031 164.812 1.00 97.34  ? 25  ILE G CA  1 
ATOM 4280 C C   . ILE C 3 25  ? 96.249  128.385 164.689 1.00 98.30  ? 25  ILE G C   1 
ATOM 4281 O O   . ILE C 3 25  ? 95.045  128.521 164.913 1.00 96.84  ? 25  ILE G O   1 
ATOM 4282 C CB  . ILE C 3 25  ? 97.337  126.502 163.419 1.00 95.27  ? 25  ILE G CB  1 
ATOM 4283 N N   . ASP C 3 26  ? 97.036  129.394 164.327 1.00 99.82  ? 26  ASP G N   1 
ATOM 4284 C CA  . ASP C 3 26  ? 96.534  130.754 164.163 1.00 97.96  ? 26  ASP G CA  1 
ATOM 4285 C C   . ASP C 3 26  ? 96.133  130.954 162.706 1.00 99.60  ? 26  ASP G C   1 
ATOM 4286 O O   . ASP C 3 26  ? 96.982  130.908 161.810 1.00 100.36 ? 26  ASP G O   1 
ATOM 4287 C CB  . ASP C 3 26  ? 97.587  131.772 164.590 1.00 96.07  ? 26  ASP G CB  1 
ATOM 4288 N N   . ARG C 3 27  ? 94.844  131.178 162.470 1.00 92.23  ? 27  ARG G N   1 
ATOM 4289 C CA  . ARG C 3 27  ? 94.312  131.370 161.131 1.00 91.17  ? 27  ARG G CA  1 
ATOM 4290 C C   . ARG C 3 27  ? 93.728  132.770 161.003 1.00 93.44  ? 27  ARG G C   1 
ATOM 4291 O O   . ARG C 3 27  ? 93.198  133.329 161.968 1.00 96.09  ? 27  ARG G O   1 
ATOM 4292 C CB  . ARG C 3 27  ? 93.241  130.323 160.804 1.00 87.03  ? 27  ARG G CB  1 
ATOM 4293 N N   . ILE C 3 28  ? 93.828  133.333 159.800 1.00 88.38  ? 28  ILE G N   1 
ATOM 4294 C CA  . ILE C 3 28  ? 93.327  134.678 159.540 1.00 87.79  ? 28  ILE G CA  1 
ATOM 4295 C C   . ILE C 3 28  ? 92.161  134.610 158.566 1.00 91.25  ? 28  ILE G C   1 
ATOM 4296 O O   . ILE C 3 28  ? 91.823  133.536 158.056 1.00 93.12  ? 28  ILE G O   1 
ATOM 4297 C CB  . ILE C 3 28  ? 94.438  135.594 158.999 1.00 90.39  ? 28  ILE G CB  1 
ATOM 4298 C CG1 . ILE C 3 28  ? 94.845  135.161 157.592 1.00 90.82  ? 28  ILE G CG1 1 
ATOM 4299 C CG2 . ILE C 3 28  ? 95.638  135.584 159.931 1.00 92.80  ? 28  ILE G CG2 1 
ATOM 4300 C CD1 . ILE C 3 28  ? 95.665  136.191 156.852 1.00 91.60  ? 28  ILE G CD1 1 
ATOM 4301 N N   . LYS C 3 29  ? 91.537  135.754 158.304 1.00 99.79  ? 29  LYS G N   1 
ATOM 4302 C CA  . LYS C 3 29  ? 90.400  135.811 157.400 1.00 99.61  ? 29  LYS G CA  1 
ATOM 4303 C C   . LYS C 3 29  ? 90.862  135.779 155.946 1.00 101.07 ? 29  LYS G C   1 
ATOM 4304 O O   . LYS C 3 29  ? 91.979  136.179 155.608 1.00 102.16 ? 29  LYS G O   1 
ATOM 4305 C CB  . LYS C 3 29  ? 89.571  137.068 157.661 1.00 97.14  ? 29  LYS G CB  1 
ATOM 4306 N N   . VAL C 3 30  ? 89.972  135.291 155.078 1.00 93.92  ? 30  VAL G N   1 
ATOM 4307 C CA  . VAL C 3 30  ? 90.288  135.188 153.657 1.00 92.87  ? 30  VAL G CA  1 
ATOM 4308 C C   . VAL C 3 30  ? 90.443  136.564 153.026 1.00 90.80  ? 30  VAL G C   1 
ATOM 4309 O O   . VAL C 3 30  ? 91.234  136.739 152.090 1.00 92.16  ? 30  VAL G O   1 
ATOM 4310 C CB  . VAL C 3 30  ? 89.218  134.352 152.936 1.00 93.04  ? 30  VAL G CB  1 
ATOM 4311 C CG1 . VAL C 3 30  ? 89.667  134.022 151.534 1.00 91.33  ? 30  VAL G CG1 1 
ATOM 4312 C CG2 . VAL C 3 30  ? 88.965  133.074 153.704 1.00 94.62  ? 30  VAL G CG2 1 
ATOM 4313 N N   . SER C 3 31  ? 89.689  137.554 153.504 1.00 95.18  ? 31  SER G N   1 
ATOM 4314 C CA  . SER C 3 31  ? 89.829  138.904 152.971 1.00 98.10  ? 31  SER G CA  1 
ATOM 4315 C C   . SER C 3 31  ? 91.238  139.436 153.195 1.00 100.67 ? 31  SER G C   1 
ATOM 4316 O O   . SER C 3 31  ? 91.797  140.114 152.325 1.00 101.63 ? 31  SER G O   1 
ATOM 4317 C CB  . SER C 3 31  ? 88.794  139.831 153.607 1.00 100.67 ? 31  SER G CB  1 
ATOM 4318 O OG  . SER C 3 31  ? 88.963  139.904 155.012 1.00 101.96 ? 31  SER G OG  1 
ATOM 4319 N N   . LYS C 3 32  ? 91.831  139.136 154.353 1.00 93.86  ? 32  LYS G N   1 
ATOM 4320 C CA  . LYS C 3 32  ? 93.193  139.586 154.627 1.00 91.32  ? 32  LYS G CA  1 
ATOM 4321 C C   . LYS C 3 32  ? 94.186  138.966 153.651 1.00 93.12  ? 32  LYS G C   1 
ATOM 4322 O O   . LYS C 3 32  ? 95.069  139.654 153.125 1.00 97.17  ? 32  LYS G O   1 
ATOM 4323 C CB  . LYS C 3 32  ? 93.574  139.253 156.069 1.00 89.71  ? 32  LYS G CB  1 
ATOM 4324 N N   . ALA C 3 33  ? 94.058  137.662 153.395 1.00 84.60  ? 33  ALA G N   1 
ATOM 4325 C CA  . ALA C 3 33  ? 94.963  137.007 152.456 1.00 85.42  ? 33  ALA G CA  1 
ATOM 4326 C C   . ALA C 3 33  ? 94.785  137.553 151.047 1.00 86.69  ? 33  ALA G C   1 
ATOM 4327 O O   . ALA C 3 33  ? 95.770  137.781 150.330 1.00 91.37  ? 33  ALA G O   1 
ATOM 4328 C CB  . ALA C 3 33  ? 94.741  135.496 152.478 1.00 84.46  ? 33  ALA G CB  1 
ATOM 4329 N N   . ALA C 3 34  ? 93.536  137.767 150.632 1.00 80.76  ? 34  ALA G N   1 
ATOM 4330 C CA  . ALA C 3 34  ? 93.284  138.334 149.314 1.00 81.05  ? 34  ALA G CA  1 
ATOM 4331 C C   . ALA C 3 34  ? 93.895  139.721 149.191 1.00 79.60  ? 34  ALA G C   1 
ATOM 4332 O O   . ALA C 3 34  ? 94.509  140.049 148.169 1.00 78.84  ? 34  ALA G O   1 
ATOM 4333 C CB  . ALA C 3 34  ? 91.781  138.383 149.047 1.00 82.63  ? 34  ALA G CB  1 
ATOM 4334 N N   . ALA C 3 35  ? 93.739  140.547 150.227 1.00 84.23  ? 35  ALA G N   1 
ATOM 4335 C CA  . ALA C 3 35  ? 94.325  141.880 150.208 1.00 85.19  ? 35  ALA G CA  1 
ATOM 4336 C C   . ALA C 3 35  ? 95.842  141.809 150.139 1.00 89.84  ? 35  ALA G C   1 
ATOM 4337 O O   . ALA C 3 35  ? 96.472  142.593 149.424 1.00 94.55  ? 35  ALA G O   1 
ATOM 4338 C CB  . ALA C 3 35  ? 93.877  142.669 151.437 1.00 85.33  ? 35  ALA G CB  1 
ATOM 4339 N N   . ASP C 3 36  ? 96.445  140.874 150.874 1.00 89.65  ? 36  ASP G N   1 
ATOM 4340 C CA  . ASP C 3 36  ? 97.898  140.736 150.846 1.00 89.31  ? 36  ASP G CA  1 
ATOM 4341 C C   . ASP C 3 36  ? 98.390  140.368 149.451 1.00 89.81  ? 36  ASP G C   1 
ATOM 4342 O O   . ASP C 3 36  ? 99.328  140.983 148.929 1.00 90.37  ? 36  ASP G O   1 
ATOM 4343 C CB  . ASP C 3 36  ? 98.345  139.693 151.870 1.00 85.82  ? 36  ASP G CB  1 
ATOM 4344 N N   . LEU C 3 37  ? 97.763  139.366 148.826 1.00 83.04  ? 37  LEU G N   1 
ATOM 4345 C CA  . LEU C 3 37  ? 98.183  138.974 147.481 1.00 78.76  ? 37  LEU G CA  1 
ATOM 4346 C C   . LEU C 3 37  ? 97.965  140.096 146.472 1.00 84.32  ? 37  LEU G C   1 
ATOM 4347 O O   . LEU C 3 37  ? 98.834  140.359 145.629 1.00 89.77  ? 37  LEU G O   1 
ATOM 4348 C CB  . LEU C 3 37  ? 97.457  137.705 147.034 1.00 77.07  ? 37  LEU G CB  1 
ATOM 4349 C CG  . LEU C 3 37  ? 98.056  136.354 147.437 1.00 82.16  ? 37  LEU G CG  1 
ATOM 4350 C CD1 . LEU C 3 37  ? 97.928  136.072 148.923 1.00 84.78  ? 37  LEU G CD1 1 
ATOM 4351 C CD2 . LEU C 3 37  ? 97.416  135.242 146.625 1.00 82.06  ? 37  LEU G CD2 1 
ATOM 4352 N N   . MET C 3 38  ? 96.813  140.770 146.538 1.00 83.74  ? 38  MET G N   1 
ATOM 4353 C CA  . MET C 3 38  ? 96.543  141.854 145.601 1.00 80.47  ? 38  MET G CA  1 
ATOM 4354 C C   . MET C 3 38  ? 97.539  142.992 145.775 1.00 82.27  ? 38  MET G C   1 
ATOM 4355 O O   . MET C 3 38  ? 98.039  143.546 144.788 1.00 84.41  ? 38  MET G O   1 
ATOM 4356 C CB  . MET C 3 38  ? 95.111  142.358 145.782 1.00 77.21  ? 38  MET G CB  1 
ATOM 4357 N N   . ALA C 3 39  ? 97.847  143.349 147.023 1.00 84.46  ? 39  ALA G N   1 
ATOM 4358 C CA  . ALA C 3 39  ? 98.810  144.411 147.275 1.00 86.46  ? 39  ALA G CA  1 
ATOM 4359 C C   . ALA C 3 39  ? 100.194 144.029 146.776 1.00 86.62  ? 39  ALA G C   1 
ATOM 4360 O O   . ALA C 3 39  ? 100.901 144.860 146.195 1.00 90.18  ? 39  ALA G O   1 
ATOM 4361 C CB  . ALA C 3 39  ? 98.849  144.739 148.767 1.00 87.53  ? 39  ALA G CB  1 
ATOM 4362 N N   . TYR C 3 40  ? 100.604 142.777 146.995 1.00 90.02  ? 40  TYR G N   1 
ATOM 4363 C CA  . TYR C 3 40  ? 101.914 142.346 146.519 1.00 88.64  ? 40  TYR G CA  1 
ATOM 4364 C C   . TYR C 3 40  ? 101.994 142.406 145.000 1.00 88.72  ? 40  TYR G C   1 
ATOM 4365 O O   . TYR C 3 40  ? 103.000 142.864 144.441 1.00 92.95  ? 40  TYR G O   1 
ATOM 4366 C CB  . TYR C 3 40  ? 102.218 140.935 147.015 1.00 86.32  ? 40  TYR G CB  1 
ATOM 4367 C CG  . TYR C 3 40  ? 103.591 140.440 146.632 1.00 87.38  ? 40  TYR G CG  1 
ATOM 4368 C CD1 . TYR C 3 40  ? 104.710 140.814 147.358 1.00 87.81  ? 40  TYR G CD1 1 
ATOM 4369 C CD2 . TYR C 3 40  ? 103.767 139.597 145.547 1.00 87.55  ? 40  TYR G CD2 1 
ATOM 4370 C CE1 . TYR C 3 40  ? 105.965 140.364 147.012 1.00 88.64  ? 40  TYR G CE1 1 
ATOM 4371 C CE2 . TYR C 3 40  ? 105.018 139.143 145.194 1.00 89.81  ? 40  TYR G CE2 1 
ATOM 4372 C CZ  . TYR C 3 40  ? 106.114 139.530 145.929 1.00 90.38  ? 40  TYR G CZ  1 
ATOM 4373 O OH  . TYR C 3 40  ? 107.365 139.078 145.580 1.00 91.89  ? 40  TYR G OH  1 
ATOM 4374 N N   . CYS C 3 41  ? 100.945 141.947 144.313 1.00 88.47  ? 41  CYS G N   1 
ATOM 4375 C CA  . CYS C 3 41  ? 100.952 141.993 142.854 1.00 90.13  ? 41  CYS G CA  1 
ATOM 4376 C C   . CYS C 3 41  ? 100.974 143.430 142.347 1.00 91.83  ? 41  CYS G C   1 
ATOM 4377 O O   . CYS C 3 41  ? 101.710 143.754 141.406 1.00 92.52  ? 41  CYS G O   1 
ATOM 4378 C CB  . CYS C 3 41  ? 99.743  141.243 142.299 1.00 90.57  ? 41  CYS G CB  1 
ATOM 4379 S SG  . CYS C 3 41  ? 99.753  139.469 142.629 1.00 95.89  ? 41  CYS G SG  1 
ATOM 4380 N N   . GLU C 3 42  ? 100.181 144.309 142.964 1.00 93.12  ? 42  GLU G N   1 
ATOM 4381 C CA  . GLU C 3 42  ? 100.169 145.707 142.548 1.00 91.68  ? 42  GLU G CA  1 
ATOM 4382 C C   . GLU C 3 42  ? 101.526 146.360 142.770 1.00 90.86  ? 42  GLU G C   1 
ATOM 4383 O O   . GLU C 3 42  ? 101.993 147.138 141.930 1.00 90.94  ? 42  GLU G O   1 
ATOM 4384 C CB  . GLU C 3 42  ? 99.076  146.468 143.297 1.00 90.68  ? 42  GLU G CB  1 
ATOM 4385 N N   . ALA C 3 43  ? 102.172 146.063 143.900 1.00 94.53  ? 43  ALA G N   1 
ATOM 4386 C CA  . ALA C 3 43  ? 103.485 146.635 144.171 1.00 94.46  ? 43  ALA G CA  1 
ATOM 4387 C C   . ALA C 3 43  ? 104.515 146.144 143.164 1.00 95.43  ? 43  ALA G C   1 
ATOM 4388 O O   . ALA C 3 43  ? 105.213 146.945 142.533 1.00 96.79  ? 43  ALA G O   1 
ATOM 4389 C CB  . ALA C 3 43  ? 103.919 146.297 145.597 1.00 95.65  ? 43  ALA G CB  1 
ATOM 4390 N N   . HIS C 3 44  ? 104.627 144.829 142.996 1.00 97.10  ? 44  HIS G N   1 
ATOM 4391 C CA  . HIS C 3 44  ? 105.539 144.276 141.996 1.00 97.89  ? 44  HIS G CA  1 
ATOM 4392 C C   . HIS C 3 44  ? 104.822 144.000 140.678 1.00 102.57 ? 44  HIS G C   1 
ATOM 4393 O O   . HIS C 3 44  ? 104.939 142.923 140.097 1.00 105.38 ? 44  HIS G O   1 
ATOM 4394 C CB  . HIS C 3 44  ? 106.196 143.011 142.532 1.00 98.69  ? 44  HIS G CB  1 
ATOM 4395 C CG  . HIS C 3 44  ? 107.063 143.238 143.729 1.00 97.80  ? 44  HIS G CG  1 
ATOM 4396 N ND1 . HIS C 3 44  ? 106.557 143.599 144.958 1.00 99.92  ? 44  HIS G ND1 1 
ATOM 4397 C CD2 . HIS C 3 44  ? 108.404 143.148 143.887 1.00 98.09  ? 44  HIS G CD2 1 
ATOM 4398 C CE1 . HIS C 3 44  ? 107.548 143.725 145.821 1.00 101.21 ? 44  HIS G CE1 1 
ATOM 4399 N NE2 . HIS C 3 44  ? 108.680 143.457 145.196 1.00 100.81 ? 44  HIS G NE2 1 
ATOM 4400 N N   . ALA C 3 45  ? 104.069 144.986 140.195 1.00 100.15 ? 45  ALA G N   1 
ATOM 4401 C CA  . ALA C 3 45  ? 103.456 144.914 138.877 1.00 99.36  ? 45  ALA G CA  1 
ATOM 4402 C C   . ALA C 3 45  ? 104.267 145.621 137.801 1.00 94.41  ? 45  ALA G C   1 
ATOM 4403 O O   . ALA C 3 45  ? 103.965 145.458 136.615 1.00 94.82  ? 45  ALA G O   1 
ATOM 4404 C CB  . ALA C 3 45  ? 102.042 145.506 138.918 1.00 97.27  ? 45  ALA G CB  1 
ATOM 4405 N N   . LYS C 3 46  ? 105.281 146.394 138.180 1.00 88.66  ? 46  LYS G N   1 
ATOM 4406 C CA  . LYS C 3 46  ? 106.093 147.143 137.233 1.00 91.27  ? 46  LYS G CA  1 
ATOM 4407 C C   . LYS C 3 46  ? 107.458 146.514 136.994 1.00 94.73  ? 46  LYS G C   1 
ATOM 4408 O O   . LYS C 3 46  ? 108.334 147.163 136.415 1.00 94.22  ? 46  LYS G O   1 
ATOM 4409 C CB  . LYS C 3 46  ? 106.263 148.585 137.714 1.00 91.62  ? 46  LYS G CB  1 
ATOM 4410 N N   . GLU C 3 47  ? 107.665 145.270 137.427 1.00 101.79 ? 47  GLU G N   1 
ATOM 4411 C CA  . GLU C 3 47  ? 108.966 144.627 137.320 1.00 101.80 ? 47  GLU G CA  1 
ATOM 4412 C C   . GLU C 3 47  ? 108.937 143.285 136.603 1.00 102.23 ? 47  GLU G C   1 
ATOM 4413 O O   . GLU C 3 47  ? 109.982 142.630 136.516 1.00 104.28 ? 47  GLU G O   1 
ATOM 4414 C CB  . GLU C 3 47  ? 109.580 144.438 138.714 1.00 101.03 ? 47  GLU G CB  1 
ATOM 4415 C CG  . GLU C 3 47  ? 109.560 145.687 139.579 1.00 104.98 ? 47  GLU G CG  1 
ATOM 4416 C CD  . GLU C 3 47  ? 110.420 146.804 139.019 1.00 106.01 ? 47  GLU G CD  1 
ATOM 4417 O OE1 . GLU C 3 47  ? 111.409 146.503 138.317 1.00 105.47 ? 47  GLU G OE1 1 
ATOM 4418 O OE2 . GLU C 3 47  ? 110.107 147.984 139.282 1.00 105.22 ? 47  GLU G OE2 1 
ATOM 4419 N N   . ASP C 3 48  ? 107.788 142.851 136.088 1.00 97.40  ? 48  ASP G N   1 
ATOM 4420 C CA  . ASP C 3 48  ? 107.704 141.562 135.417 1.00 96.90  ? 48  ASP G CA  1 
ATOM 4421 C C   . ASP C 3 48  ? 107.742 141.757 133.911 1.00 96.74  ? 48  ASP G C   1 
ATOM 4422 O O   . ASP C 3 48  ? 106.781 142.296 133.340 1.00 102.35 ? 48  ASP G O   1 
ATOM 4423 C CB  . ASP C 3 48  ? 106.436 140.824 135.828 1.00 96.66  ? 48  ASP G CB  1 
ATOM 4424 C CG  . ASP C 3 48  ? 105.219 141.720 135.844 1.00 101.73 ? 48  ASP G CG  1 
ATOM 4425 O OD1 . ASP C 3 48  ? 105.389 142.957 135.834 1.00 102.84 ? 48  ASP G OD1 1 
ATOM 4426 O OD2 . ASP C 3 48  ? 104.091 141.187 135.883 1.00 103.49 ? 48  ASP G OD2 1 
ATOM 4427 N N   . PRO C 3 49  ? 108.820 141.350 133.235 1.00 85.17  ? 49  PRO G N   1 
ATOM 4428 C CA  . PRO C 3 49  ? 108.907 141.551 131.780 1.00 87.90  ? 49  PRO G CA  1 
ATOM 4429 C C   . PRO C 3 49  ? 107.861 140.797 130.977 1.00 87.56  ? 49  PRO G C   1 
ATOM 4430 O O   . PRO C 3 49  ? 107.545 141.228 129.861 1.00 90.32  ? 49  PRO G O   1 
ATOM 4431 C CB  . PRO C 3 49  ? 110.321 141.059 131.440 1.00 89.09  ? 49  PRO G CB  1 
ATOM 4432 C CG  . PRO C 3 49  ? 111.062 141.076 132.737 1.00 91.15  ? 49  PRO G CG  1 
ATOM 4433 C CD  . PRO C 3 49  ? 110.050 140.766 133.788 1.00 88.63  ? 49  PRO G CD  1 
ATOM 4434 N N   . LEU C 3 50  ? 107.325 139.691 131.489 1.00 82.21  ? 50  LEU G N   1 
ATOM 4435 C CA  . LEU C 3 50  ? 106.312 138.952 130.745 1.00 83.35  ? 50  LEU G CA  1 
ATOM 4436 C C   . LEU C 3 50  ? 105.028 139.757 130.581 1.00 90.51  ? 50  LEU G C   1 
ATOM 4437 O O   . LEU C 3 50  ? 104.450 139.790 129.489 1.00 94.20  ? 50  LEU G O   1 
ATOM 4438 C CB  . LEU C 3 50  ? 106.019 137.621 131.437 1.00 86.83  ? 50  LEU G CB  1 
ATOM 4439 C CG  . LEU C 3 50  ? 106.831 136.397 131.011 1.00 87.17  ? 50  LEU G CG  1 
ATOM 4440 C CD1 . LEU C 3 50  ? 108.276 136.522 131.428 1.00 87.23  ? 50  LEU G CD1 1 
ATOM 4441 C CD2 . LEU C 3 50  ? 106.220 135.146 131.614 1.00 86.97  ? 50  LEU G CD2 1 
ATOM 4442 N N   . LEU C 3 51  ? 104.566 140.406 131.651 1.00 88.40  ? 51  LEU G N   1 
ATOM 4443 C CA  . LEU C 3 51  ? 103.325 141.170 131.579 1.00 84.60  ? 51  LEU G CA  1 
ATOM 4444 C C   . LEU C 3 51  ? 103.472 142.382 130.667 1.00 90.85  ? 51  LEU G C   1 
ATOM 4445 O O   . LEU C 3 51  ? 102.659 142.592 129.761 1.00 90.69  ? 51  LEU G O   1 
ATOM 4446 C CB  . LEU C 3 51  ? 102.902 141.594 132.985 1.00 84.47  ? 51  LEU G CB  1 
ATOM 4447 C CG  . LEU C 3 51  ? 101.538 142.245 133.196 1.00 88.47  ? 51  LEU G CG  1 
ATOM 4448 C CD1 . LEU C 3 51  ? 100.988 141.844 134.549 1.00 88.76  ? 51  LEU G CD1 1 
ATOM 4449 C CD2 . LEU C 3 51  ? 101.632 143.759 133.096 1.00 88.59  ? 51  LEU G CD2 1 
ATOM 4450 N N   . THR C 3 52  ? 104.508 143.187 130.888 1.00 104.65 ? 52  THR G N   1 
ATOM 4451 C CA  . THR C 3 52  ? 104.746 144.383 130.089 1.00 104.49 ? 52  THR G CA  1 
ATOM 4452 C C   . THR C 3 52  ? 105.961 144.161 129.202 1.00 103.22 ? 52  THR G C   1 
ATOM 4453 O O   . THR C 3 52  ? 107.082 144.039 129.721 1.00 104.22 ? 52  THR G O   1 
ATOM 4454 C CB  . THR C 3 52  ? 104.960 145.603 130.985 1.00 101.45 ? 52  THR G CB  1 
ATOM 4455 N N   . PRO C 3 53  ? 105.798 144.087 127.881 1.00 108.43 ? 53  PRO G N   1 
ATOM 4456 C CA  . PRO C 3 53  ? 106.957 143.861 127.010 1.00 109.05 ? 53  PRO G CA  1 
ATOM 4457 C C   . PRO C 3 53  ? 107.996 144.961 127.171 1.00 111.02 ? 53  PRO G C   1 
ATOM 4458 O O   . PRO C 3 53  ? 107.668 146.144 127.275 1.00 111.92 ? 53  PRO G O   1 
ATOM 4459 C CB  . PRO C 3 53  ? 106.349 143.858 125.603 1.00 109.78 ? 53  PRO G CB  1 
ATOM 4460 C CG  . PRO C 3 53  ? 104.913 143.513 125.813 1.00 109.02 ? 53  PRO G CG  1 
ATOM 4461 C CD  . PRO C 3 53  ? 104.537 144.131 127.125 1.00 109.34 ? 53  PRO G CD  1 
ATOM 4462 N N   . VAL C 3 54  ? 109.259 144.553 127.190 1.00 108.53 ? 54  VAL G N   1 
ATOM 4463 C CA  . VAL C 3 54  ? 110.376 145.461 127.430 1.00 108.45 ? 54  VAL G CA  1 
ATOM 4464 C C   . VAL C 3 54  ? 110.831 146.053 126.102 1.00 108.36 ? 54  VAL G C   1 
ATOM 4465 O O   . VAL C 3 54  ? 110.476 145.527 125.037 1.00 105.74 ? 54  VAL G O   1 
ATOM 4466 C CB  . VAL C 3 54  ? 111.530 144.741 128.145 1.00 106.37 ? 54  VAL G CB  1 
ATOM 4467 N N   . PRO C 3 55  ? 111.588 147.151 126.111 1.00 115.77 ? 55  PRO G N   1 
ATOM 4468 C CA  . PRO C 3 55  ? 112.173 147.647 124.861 1.00 116.66 ? 55  PRO G CA  1 
ATOM 4469 C C   . PRO C 3 55  ? 113.067 146.597 124.220 1.00 115.79 ? 55  PRO G C   1 
ATOM 4470 O O   . PRO C 3 55  ? 113.689 145.777 124.900 1.00 116.29 ? 55  PRO G O   1 
ATOM 4471 C CB  . PRO C 3 55  ? 112.987 148.871 125.298 1.00 115.75 ? 55  PRO G CB  1 
ATOM 4472 C CG  . PRO C 3 55  ? 112.550 149.204 126.677 1.00 115.30 ? 55  PRO G CG  1 
ATOM 4473 C CD  . PRO C 3 55  ? 111.656 148.134 127.206 1.00 114.85 ? 55  PRO G CD  1 
ATOM 4474 N N   . ALA C 3 56  ? 113.120 146.627 122.886 1.00 105.57 ? 56  ALA G N   1 
ATOM 4475 C CA  . ALA C 3 56  ? 113.921 145.659 122.146 1.00 105.41 ? 56  ALA G CA  1 
ATOM 4476 C C   . ALA C 3 56  ? 115.409 145.784 122.446 1.00 105.69 ? 56  ALA G C   1 
ATOM 4477 O O   . ALA C 3 56  ? 116.167 144.850 122.163 1.00 104.10 ? 56  ALA G O   1 
ATOM 4478 C CB  . ALA C 3 56  ? 113.679 145.815 120.644 1.00 103.40 ? 56  ALA G CB  1 
ATOM 4479 N N   . SER C 3 57  ? 115.845 146.909 123.006 1.00 101.98 ? 57  SER G N   1 
ATOM 4480 C CA  . SER C 3 57  ? 117.236 147.094 123.392 1.00 100.84 ? 57  SER G CA  1 
ATOM 4481 C C   . SER C 3 57  ? 117.554 146.498 124.756 1.00 100.87 ? 57  SER G C   1 
ATOM 4482 O O   . SER C 3 57  ? 118.723 146.491 125.155 1.00 101.88 ? 57  SER G O   1 
ATOM 4483 C CB  . SER C 3 57  ? 117.589 148.584 123.389 1.00 101.92 ? 57  SER G CB  1 
ATOM 4484 O OG  . SER C 3 57  ? 116.791 149.298 124.317 1.00 101.39 ? 57  SER G OG  1 
ATOM 4485 N N   . GLU C 3 58  ? 116.550 146.003 125.479 1.00 100.95 ? 58  GLU G N   1 
ATOM 4486 C CA  . GLU C 3 58  ? 116.752 145.407 126.792 1.00 99.62  ? 58  GLU G CA  1 
ATOM 4487 C C   . GLU C 3 58  ? 116.561 143.899 126.814 1.00 100.26 ? 58  GLU G C   1 
ATOM 4488 O O   . GLU C 3 58  ? 117.156 143.229 127.659 1.00 98.03  ? 58  GLU G O   1 
ATOM 4489 C CB  . GLU C 3 58  ? 115.802 146.040 127.816 1.00 98.20  ? 58  GLU G CB  1 
ATOM 4490 N N   . ASN C 3 59  ? 115.752 143.355 125.916 1.00 97.08  ? 59  ASN G N   1 
ATOM 4491 C CA  . ASN C 3 59  ? 115.545 141.913 125.853 1.00 95.65  ? 59  ASN G CA  1 
ATOM 4492 C C   . ASN C 3 59  ? 116.772 141.244 125.250 1.00 96.26  ? 59  ASN G C   1 
ATOM 4493 O O   . ASN C 3 59  ? 117.136 141.555 124.108 1.00 96.12  ? 59  ASN G O   1 
ATOM 4494 C CB  . ASN C 3 59  ? 114.304 141.601 125.023 1.00 95.22  ? 59  ASN G CB  1 
ATOM 4495 C CG  . ASN C 3 59  ? 113.874 140.152 125.132 1.00 97.43  ? 59  ASN G CG  1 
ATOM 4496 O OD1 . ASN C 3 59  ? 114.493 139.357 125.838 1.00 97.64  ? 59  ASN G OD1 1 
ATOM 4497 N ND2 . ASN C 3 59  ? 112.805 139.800 124.426 1.00 96.49  ? 59  ASN G ND2 1 
ATOM 4498 N N   . PRO C 3 60  ? 117.436 140.333 125.960 1.00 81.78  ? 60  PRO G N   1 
ATOM 4499 C CA  . PRO C 3 60  ? 118.630 139.677 125.417 1.00 78.77  ? 60  PRO G CA  1 
ATOM 4500 C C   . PRO C 3 60  ? 118.372 138.367 124.689 1.00 79.06  ? 60  PRO G C   1 
ATOM 4501 O O   . PRO C 3 60  ? 119.339 137.703 124.300 1.00 82.02  ? 60  PRO G O   1 
ATOM 4502 C CB  . PRO C 3 60  ? 119.467 139.433 126.677 1.00 78.59  ? 60  PRO G CB  1 
ATOM 4503 C CG  . PRO C 3 60  ? 118.465 139.240 127.758 1.00 81.61  ? 60  PRO G CG  1 
ATOM 4504 C CD  . PRO C 3 60  ? 117.209 139.982 127.372 1.00 82.56  ? 60  PRO G CD  1 
ATOM 4505 N N   . PHE C 3 61  ? 117.118 137.977 124.494 1.00 74.27  ? 61  PHE G N   1 
ATOM 4506 C CA  . PHE C 3 61  ? 116.813 136.712 123.838 1.00 74.52  ? 61  PHE G CA  1 
ATOM 4507 C C   . PHE C 3 61  ? 116.337 136.933 122.407 1.00 76.43  ? 61  PHE G C   1 
ATOM 4508 O O   . PHE C 3 61  ? 116.933 137.702 121.654 1.00 74.46  ? 61  PHE G O   1 
ATOM 4509 C CB  . PHE C 3 61  ? 115.756 135.941 124.630 1.00 75.95  ? 61  PHE G CB  1 
ATOM 4510 C CG  . PHE C 3 61  ? 116.304 135.210 125.820 1.00 76.96  ? 61  PHE G CG  1 
ATOM 4511 C CD1 . PHE C 3 61  ? 116.959 134.004 125.668 1.00 76.05  ? 61  PHE G CD1 1 
ATOM 4512 C CD2 . PHE C 3 61  ? 116.169 135.733 127.093 1.00 75.47  ? 61  PHE G CD2 1 
ATOM 4513 C CE1 . PHE C 3 61  ? 117.465 133.336 126.762 1.00 75.59  ? 61  PHE G CE1 1 
ATOM 4514 C CE2 . PHE C 3 61  ? 116.673 135.067 128.186 1.00 67.24  ? 61  PHE G CE2 1 
ATOM 4515 C CZ  . PHE C 3 61  ? 117.321 133.870 128.020 1.00 69.06  ? 61  PHE G CZ  1 
ATOM 4516 N N   . SER D 4 12  ? 112.052 115.577 53.788  1.00 30.00  ? 12  SER R N   1 
ATOM 4517 C CA  . SER D 4 12  ? 111.127 115.700 52.669  1.00 30.00  ? 12  SER R CA  1 
ATOM 4518 C C   . SER D 4 12  ? 109.978 114.711 52.795  1.00 30.00  ? 12  SER R C   1 
ATOM 4519 O O   . SER D 4 12  ? 109.511 114.167 51.796  1.00 30.00  ? 12  SER R O   1 
ATOM 4520 C CB  . SER D 4 12  ? 111.859 115.484 51.346  1.00 30.00  ? 12  SER R CB  1 
ATOM 4521 O OG  . SER D 4 12  ? 112.412 114.181 51.280  1.00 30.00  ? 12  SER R OG  1 
ATOM 4522 N N   . CYS D 4 13  ? 109.524 114.467 54.018  1.00 84.08  ? 13  CYS R N   1 
ATOM 4523 C CA  . CYS D 4 13  ? 108.399 113.560 54.217  1.00 85.20  ? 13  CYS R CA  1 
ATOM 4524 C C   . CYS D 4 13  ? 107.323 114.195 55.096  1.00 85.80  ? 13  CYS R C   1 
ATOM 4525 O O   . CYS D 4 13  ? 107.191 113.830 56.263  1.00 86.90  ? 13  CYS R O   1 
ATOM 4526 C CB  . CYS D 4 13  ? 108.866 112.219 54.816  1.00 30.00  ? 13  CYS R CB  1 
ATOM 4527 S SG  . CYS D 4 13  ? 110.122 111.307 53.868  1.00 30.00  ? 13  CYS R SG  1 
ATOM 4528 N N   . THR D 4 14  ? 106.561 115.135 54.551  1.00 82.20  ? 14  THR R N   1 
ATOM 4529 C CA  . THR D 4 14  ? 105.466 115.743 55.307  1.00 79.86  ? 14  THR R CA  1 
ATOM 4530 C C   . THR D 4 14  ? 104.755 114.566 55.802  1.00 73.18  ? 14  THR R C   1 
ATOM 4531 O O   . THR D 4 14  ? 104.151 113.827 55.027  1.00 71.00  ? 14  THR R O   1 
ATOM 4532 C CB  . THR D 4 14  ? 104.510 116.521 54.377  1.00 79.83  ? 14  THR R CB  1 
ATOM 4533 N N   . ILE D 4 15  ? 104.780 114.371 57.097  1.00 69.72  ? 15  ILE R N   1 
ATOM 4534 C CA  . ILE D 4 15  ? 103.866 113.426 57.642  1.00 70.07  ? 15  ILE R CA  1 
ATOM 4535 C C   . ILE D 4 15  ? 102.616 114.111 58.117  1.00 71.99  ? 15  ILE R C   1 
ATOM 4536 O O   . ILE D 4 15  ? 102.659 115.237 58.613  1.00 74.46  ? 15  ILE R O   1 
ATOM 4537 C CB  . ILE D 4 15  ? 104.477 112.658 58.829  1.00 68.89  ? 15  ILE R CB  1 
ATOM 4538 N N   . ASP D 4 16  ? 101.498 113.432 57.959  1.00 80.96  ? 16  ASP R N   1 
ATOM 4539 C CA  . ASP D 4 16  ? 100.248 113.973 58.420  1.00 80.10  ? 16  ASP R CA  1 
ATOM 4540 C C   . ASP D 4 16  ? 100.203 113.797 59.918  1.00 82.48  ? 16  ASP R C   1 
ATOM 4541 O O   . ASP D 4 16  ? 100.902 112.939 60.461  1.00 85.72  ? 16  ASP R O   1 
ATOM 4542 C CB  . ASP D 4 16  ? 99.142  113.198 57.751  1.00 80.53  ? 16  ASP R CB  1 
ATOM 4543 C CG  . ASP D 4 16  ? 97.799  113.759 58.003  1.00 81.33  ? 16  ASP R CG  1 
ATOM 4544 O OD1 . ASP D 4 16  ? 97.490  114.055 59.145  1.00 79.78  ? 16  ASP R OD1 1 
ATOM 4545 O OD2 . ASP D 4 16  ? 97.021  113.884 57.050  1.00 82.82  ? 16  ASP R OD2 1 
ATOM 4546 N N   . HIS D 4 17  ? 99.396  114.594 60.602  1.00 80.84  ? 17  HIS R N   1 
ATOM 4547 C CA  . HIS D 4 17  ? 99.340  114.486 62.001  1.00 84.95  ? 17  HIS R CA  1 
ATOM 4548 C C   . HIS D 4 17  ? 97.976  114.895 62.368  1.00 88.44  ? 17  HIS R C   1 
ATOM 4549 O O   . HIS D 4 17  ? 97.774  115.817 63.140  1.00 94.30  ? 17  HIS R O   1 
ATOM 4550 C CB  . HIS D 4 17  ? 100.316 115.409 62.645  1.00 85.58  ? 17  HIS R CB  1 
ATOM 4551 C CG  . HIS D 4 17  ? 100.282 116.738 62.010  1.00 89.16  ? 17  HIS R CG  1 
ATOM 4552 N ND1 . HIS D 4 17  ? 100.735 116.939 60.732  1.00 90.66  ? 17  HIS R ND1 1 
ATOM 4553 C CD2 . HIS D 4 17  ? 99.724  117.896 62.404  1.00 90.34  ? 17  HIS R CD2 1 
ATOM 4554 C CE1 . HIS D 4 17  ? 100.517 118.189 60.388  1.00 90.38  ? 17  HIS R CE1 1 
ATOM 4555 N NE2 . HIS D 4 17  ? 99.879  118.779 61.375  1.00 92.55  ? 17  HIS R NE2 1 
ATOM 4556 N N   . THR D 4 18  ? 96.995  114.210 61.836  1.00 83.37  ? 18  THR R N   1 
ATOM 4557 C CA  . THR D 4 18  ? 95.658  114.543 62.229  1.00 85.54  ? 18  THR R CA  1 
ATOM 4558 C C   . THR D 4 18  ? 95.493  114.240 63.713  1.00 86.61  ? 18  THR R C   1 
ATOM 4559 O O   . THR D 4 18  ? 95.022  115.066 64.471  1.00 87.17  ? 18  THR R O   1 
ATOM 4560 C CB  . THR D 4 18  ? 94.653  113.727 61.414  1.00 83.61  ? 18  THR R CB  1 
ATOM 4561 N N   . ILE D 4 19  ? 95.967  113.085 64.153  1.00 82.41  ? 19  ILE R N   1 
ATOM 4562 C CA  . ILE D 4 19  ? 95.802  112.678 65.541  1.00 80.00  ? 19  ILE R CA  1 
ATOM 4563 C C   . ILE D 4 19  ? 96.522  113.595 66.471  1.00 75.18  ? 19  ILE R C   1 
ATOM 4564 O O   . ILE D 4 19  ? 96.009  113.944 67.491  1.00 76.61  ? 19  ILE R O   1 
ATOM 4565 C CB  . ILE D 4 19  ? 96.309  111.240 65.769  1.00 80.35  ? 19  ILE R CB  1 
ATOM 4566 N N   . HIS D 4 20  ? 97.686  114.023 66.074  1.00 81.71  ? 20  HIS R N   1 
ATOM 4567 C CA  . HIS D 4 20  ? 98.486  114.924 66.890  1.00 89.00  ? 20  HIS R CA  1 
ATOM 4568 C C   . HIS D 4 20  ? 97.719  116.186 67.260  1.00 89.73  ? 20  HIS R C   1 
ATOM 4569 O O   . HIS D 4 20  ? 98.017  116.803 68.287  1.00 93.70  ? 20  HIS R O   1 
ATOM 4570 C CB  . HIS D 4 20  ? 99.770  115.289 66.142  1.00 90.91  ? 20  HIS R CB  1 
ATOM 4571 C CG  . HIS D 4 20  ? 100.753 116.071 66.956  1.00 90.60  ? 20  HIS R CG  1 
ATOM 4572 N ND1 . HIS D 4 20  ? 101.832 116.717 66.394  1.00 87.57  ? 20  HIS R ND1 1 
ATOM 4573 C CD2 . HIS D 4 20  ? 100.853 116.265 68.292  1.00 91.01  ? 20  HIS R CD2 1 
ATOM 4574 C CE1 . HIS D 4 20  ? 102.534 117.306 67.345  1.00 89.46  ? 20  HIS R CE1 1 
ATOM 4575 N NE2 . HIS D 4 20  ? 101.962 117.046 68.506  1.00 90.77  ? 20  HIS R NE2 1 
ATOM 4576 N N   . GLN D 4 21  ? 96.736  116.577 66.455  1.00 87.83  ? 21  GLN R N   1 
ATOM 4577 C CA  . GLN D 4 21  ? 95.989  117.805 66.675  1.00 89.17  ? 21  GLN R CA  1 
ATOM 4578 C C   . GLN D 4 21  ? 94.597  117.565 67.253  1.00 89.38  ? 21  GLN R C   1 
ATOM 4579 O O   . GLN D 4 21  ? 93.827  118.519 67.394  1.00 88.32  ? 21  GLN R O   1 
ATOM 4580 C CB  . GLN D 4 21  ? 95.886  118.592 65.367  1.00 84.79  ? 21  GLN R CB  1 
ATOM 4581 N N   . THR D 4 22  ? 94.257  116.324 67.600  1.00 79.21  ? 22  THR R N   1 
ATOM 4582 C CA  . THR D 4 22  ? 92.909  115.994 68.045  1.00 76.68  ? 22  THR R CA  1 
ATOM 4583 C C   . THR D 4 22  ? 92.860  115.567 69.506  1.00 75.83  ? 22  THR R C   1 
ATOM 4584 O O   . THR D 4 22  ? 92.119  116.154 70.297  1.00 77.10  ? 22  THR R O   1 
ATOM 4585 C CB  . THR D 4 22  ? 92.322  114.892 67.152  1.00 77.97  ? 22  THR R CB  1 
ATOM 4586 N N   . LEU D 4 23  ? 93.631  114.553 69.891  1.00 71.74  ? 23  LEU R N   1 
ATOM 4587 C CA  . LEU D 4 23  ? 93.602  114.063 71.261  1.00 71.82  ? 23  LEU R CA  1 
ATOM 4588 C C   . LEU D 4 23  ? 94.590  114.774 72.169  1.00 72.41  ? 23  LEU R C   1 
ATOM 4589 O O   . LEU D 4 23  ? 94.448  114.698 73.395  1.00 76.36  ? 23  LEU R O   1 
ATOM 4590 C CB  . LEU D 4 23  ? 93.890  112.561 71.295  1.00 67.71  ? 23  LEU R CB  1 
ATOM 4591 N N   . ALA D 4 24  ? 95.581  115.454 71.602  1.00 65.81  ? 24  ALA R N   1 
ATOM 4592 C CA  . ALA D 4 24  ? 96.602  116.104 72.421  1.00 63.54  ? 24  ALA R CA  1 
ATOM 4593 C C   . ALA D 4 24  ? 96.056  117.195 73.333  1.00 63.17  ? 24  ALA R C   1 
ATOM 4594 O O   . ALA D 4 24  ? 96.405  117.193 74.528  1.00 69.73  ? 24  ALA R O   1 
ATOM 4595 C CB  . ALA D 4 24  ? 97.712  116.643 71.515  1.00 64.63  ? 24  ALA R CB  1 
ATOM 4596 N N   . PRO D 4 25  ? 95.244  118.155 72.865  1.00 62.88  ? 25  PRO R N   1 
ATOM 4597 C CA  . PRO D 4 25  ? 94.853  119.249 73.772  1.00 68.02  ? 25  PRO R CA  1 
ATOM 4598 C C   . PRO D 4 25  ? 94.071  118.786 74.983  1.00 66.86  ? 25  PRO R C   1 
ATOM 4599 O O   . PRO D 4 25  ? 94.294  119.299 76.087  1.00 68.49  ? 25  PRO R O   1 
ATOM 4600 C CB  . PRO D 4 25  ? 94.022  120.185 72.884  1.00 67.60  ? 25  PRO R CB  1 
ATOM 4601 C CG  . PRO D 4 25  ? 93.834  119.513 71.599  1.00 67.68  ? 25  PRO R CG  1 
ATOM 4602 C CD  . PRO D 4 25  ? 94.557  118.227 71.562  1.00 66.35  ? 25  PRO R CD  1 
ATOM 4603 N N   . VAL D 4 26  ? 93.166  117.823 74.813  1.00 57.78  ? 26  VAL R N   1 
ATOM 4604 C CA  . VAL D 4 26  ? 92.365  117.355 75.940  1.00 58.52  ? 26  VAL R CA  1 
ATOM 4605 C C   . VAL D 4 26  ? 93.266  116.749 77.001  1.00 58.32  ? 26  VAL R C   1 
ATOM 4606 O O   . VAL D 4 26  ? 93.152  117.057 78.195  1.00 64.18  ? 26  VAL R O   1 
ATOM 4607 C CB  . VAL D 4 26  ? 91.301  116.351 75.464  1.00 58.81  ? 26  VAL R CB  1 
ATOM 4608 N N   . VAL D 4 27  ? 94.194  115.896 76.575  1.00 55.74  ? 27  VAL R N   1 
ATOM 4609 C CA  . VAL D 4 27  ? 95.099  115.256 77.519  1.00 56.20  ? 27  VAL R CA  1 
ATOM 4610 C C   . VAL D 4 27  ? 95.968  116.291 78.212  1.00 57.70  ? 27  VAL R C   1 
ATOM 4611 O O   . VAL D 4 27  ? 96.153  116.244 79.431  1.00 60.85  ? 27  VAL R O   1 
ATOM 4612 C CB  . VAL D 4 27  ? 95.945  114.189 76.805  1.00 60.16  ? 27  VAL R CB  1 
ATOM 4613 C CG1 . VAL D 4 27  ? 96.961  113.598 77.764  1.00 63.15  ? 27  VAL R CG1 1 
ATOM 4614 C CG2 . VAL D 4 27  ? 95.037  113.107 76.244  1.00 59.69  ? 27  VAL R CG2 1 
ATOM 4615 N N   . TYR D 4 28  ? 96.507  117.247 77.456  1.00 59.04  ? 28  TYR R N   1 
ATOM 4616 C CA  . TYR D 4 28  ? 97.408  118.226 78.054  1.00 58.49  ? 28  TYR R CA  1 
ATOM 4617 C C   . TYR D 4 28  ? 96.683  119.080 79.089  1.00 59.47  ? 28  TYR R C   1 
ATOM 4618 O O   . TYR D 4 28  ? 97.188  119.293 80.200  1.00 65.48  ? 28  TYR R O   1 
ATOM 4619 C CB  . TYR D 4 28  ? 98.027  119.100 76.965  1.00 59.99  ? 28  TYR R CB  1 
ATOM 4620 C CG  . TYR D 4 28  ? 99.151  118.431 76.210  1.00 59.50  ? 28  TYR R CG  1 
ATOM 4621 C CD1 . TYR D 4 28  ? 99.941  117.470 76.808  1.00 55.95  ? 28  TYR R CD1 1 
ATOM 4622 C CD2 . TYR D 4 28  ? 99.400  118.748 74.884  1.00 64.53  ? 28  TYR R CD2 1 
ATOM 4623 C CE1 . TYR D 4 28  ? 100.959 116.854 76.110  1.00 60.90  ? 28  TYR R CE1 1 
ATOM 4624 C CE2 . TYR D 4 28  ? 100.413 118.138 74.181  1.00 60.57  ? 28  TYR R CE2 1 
ATOM 4625 C CZ  . TYR D 4 28  ? 101.187 117.192 74.797  1.00 60.28  ? 28  TYR R CZ  1 
ATOM 4626 O OH  . TYR D 4 28  ? 102.195 116.587 74.091  1.00 60.36  ? 28  TYR R OH  1 
ATOM 4627 N N   . VAL D 4 29  ? 95.482  119.560 78.753  1.00 49.91  ? 29  VAL R N   1 
ATOM 4628 C CA  . VAL D 4 29  ? 94.764  120.423 79.685  1.00 49.93  ? 29  VAL R CA  1 
ATOM 4629 C C   . VAL D 4 29  ? 94.322  119.637 80.913  1.00 55.68  ? 29  VAL R C   1 
ATOM 4630 O O   . VAL D 4 29  ? 94.409  120.134 82.045  1.00 64.05  ? 29  VAL R O   1 
ATOM 4631 C CB  . VAL D 4 29  ? 93.582  121.125 78.989  1.00 56.94  ? 29  VAL R CB  1 
ATOM 4632 C CG1 . VAL D 4 29  ? 92.525  120.132 78.535  1.00 56.58  ? 29  VAL R CG1 1 
ATOM 4633 C CG2 . VAL D 4 29  ? 92.970  122.165 79.914  1.00 61.25  ? 29  VAL R CG2 1 
ATOM 4634 N N   . THR D 4 30  ? 93.856  118.398 80.722  1.00 52.70  ? 30  THR R N   1 
ATOM 4635 C CA  . THR D 4 30  ? 93.463  117.587 81.866  1.00 51.48  ? 30  THR R CA  1 
ATOM 4636 C C   . THR D 4 30  ? 94.650  117.320 82.773  1.00 56.37  ? 30  THR R C   1 
ATOM 4637 O O   . THR D 4 30  ? 94.535  117.415 84.001  1.00 59.82  ? 30  THR R O   1 
ATOM 4638 C CB  . THR D 4 30  ? 92.844  116.272 81.396  1.00 54.68  ? 30  THR R CB  1 
ATOM 4639 N N   . VAL D 4 31  ? 95.806  116.998 82.187  1.00 53.58  ? 31  VAL R N   1 
ATOM 4640 C CA  . VAL D 4 31  ? 96.987  116.723 82.993  1.00 54.02  ? 31  VAL R CA  1 
ATOM 4641 C C   . VAL D 4 31  ? 97.379  117.952 83.788  1.00 51.82  ? 31  VAL R C   1 
ATOM 4642 O O   . VAL D 4 31  ? 97.642  117.866 84.990  1.00 57.15  ? 31  VAL R O   1 
ATOM 4643 C CB  . VAL D 4 31  ? 98.146  116.225 82.113  1.00 52.86  ? 31  VAL R CB  1 
ATOM 4644 C CG1 . VAL D 4 31  ? 99.436  116.234 82.901  1.00 56.90  ? 31  VAL R CG1 1 
ATOM 4645 C CG2 . VAL D 4 31  ? 97.859  114.823 81.611  1.00 54.19  ? 31  VAL R CG2 1 
ATOM 4646 N N   . LEU D 4 32  ? 97.390  119.120 83.146  1.00 53.14  ? 32  LEU R N   1 
ATOM 4647 C CA  . LEU D 4 32  ? 97.775  120.337 83.853  1.00 50.74  ? 32  LEU R CA  1 
ATOM 4648 C C   . LEU D 4 32  ? 96.837  120.608 85.024  1.00 60.02  ? 32  LEU R C   1 
ATOM 4649 O O   . LEU D 4 32  ? 97.282  120.781 86.172  1.00 67.78  ? 32  LEU R O   1 
ATOM 4650 C CB  . LEU D 4 32  ? 97.787  121.511 82.881  1.00 41.00  ? 32  LEU R CB  1 
ATOM 4651 C CG  . LEU D 4 32  ? 98.232  122.861 83.417  1.00 51.99  ? 32  LEU R CG  1 
ATOM 4652 C CD1 . LEU D 4 32  ? 99.670  122.783 83.877  1.00 57.36  ? 32  LEU R CD1 1 
ATOM 4653 C CD2 . LEU D 4 32  ? 98.071  123.924 82.347  1.00 57.92  ? 32  LEU R CD2 1 
ATOM 4654 N N   . VAL D 4 33  ? 95.525  120.592 84.757  1.00 61.87  ? 33  VAL R N   1 
ATOM 4655 C CA  . VAL D 4 33  ? 94.540  120.960 85.773  1.00 56.69  ? 33  VAL R CA  1 
ATOM 4656 C C   . VAL D 4 33  ? 94.570  119.980 86.939  1.00 56.04  ? 33  VAL R C   1 
ATOM 4657 O O   . VAL D 4 33  ? 94.564  120.381 88.108  1.00 60.15  ? 33  VAL R O   1 
ATOM 4658 C CB  . VAL D 4 33  ? 93.136  121.049 85.151  1.00 59.75  ? 33  VAL R CB  1 
ATOM 4659 C CG1 . VAL D 4 33  ? 92.088  121.189 86.234  1.00 64.12  ? 33  VAL R CG1 1 
ATOM 4660 C CG2 . VAL D 4 33  ? 93.063  122.217 84.180  1.00 60.74  ? 33  VAL R CG2 1 
ATOM 4661 N N   . VAL D 4 34  ? 94.603  118.680 86.644  1.00 57.77  ? 34  VAL R N   1 
ATOM 4662 C CA  . VAL D 4 34  ? 94.585  117.687 87.712  1.00 61.57  ? 34  VAL R CA  1 
ATOM 4663 C C   . VAL D 4 34  ? 95.906  117.678 88.472  1.00 65.40  ? 34  VAL R C   1 
ATOM 4664 O O   . VAL D 4 34  ? 95.928  117.494 89.694  1.00 68.54  ? 34  VAL R O   1 
ATOM 4665 C CB  . VAL D 4 34  ? 94.247  116.298 87.140  1.00 66.54  ? 34  VAL R CB  1 
ATOM 4666 C CG1 . VAL D 4 34  ? 94.329  115.237 88.224  1.00 66.60  ? 34  VAL R CG1 1 
ATOM 4667 C CG2 . VAL D 4 34  ? 92.861  116.309 86.514  1.00 67.44  ? 34  VAL R CG2 1 
ATOM 4668 N N   . GLY D 4 35  ? 97.023  117.889 87.779  1.00 64.10  ? 35  GLY R N   1 
ATOM 4669 C CA  . GLY D 4 35  ? 98.318  117.619 88.360  1.00 66.48  ? 35  GLY R CA  1 
ATOM 4670 C C   . GLY D 4 35  ? 99.076  118.772 88.977  1.00 66.71  ? 35  GLY R C   1 
ATOM 4671 O O   . GLY D 4 35  ? 100.086 118.531 89.643  1.00 71.87  ? 35  GLY R O   1 
ATOM 4672 N N   . PHE D 4 36  ? 98.644  120.025 88.785  1.00 59.33  ? 36  PHE R N   1 
ATOM 4673 C CA  . PHE D 4 36  ? 99.310  121.100 89.520  1.00 61.22  ? 36  PHE R CA  1 
ATOM 4674 C C   . PHE D 4 36  ? 98.964  121.073 91.006  1.00 68.06  ? 36  PHE R C   1 
ATOM 4675 O O   . PHE D 4 36  ? 99.882  120.929 91.838  1.00 73.37  ? 36  PHE R O   1 
ATOM 4676 C CB  . PHE D 4 36  ? 99.015  122.452 88.872  1.00 64.35  ? 36  PHE R CB  1 
ATOM 4677 C CG  . PHE D 4 36  ? 99.948  123.542 89.308  1.00 63.54  ? 36  PHE R CG  1 
ATOM 4678 C CD1 . PHE D 4 36  ? 99.657  124.318 90.412  1.00 65.73  ? 36  PHE R CD1 1 
ATOM 4679 C CD2 . PHE D 4 36  ? 101.117 123.784 88.617  1.00 67.13  ? 36  PHE R CD2 1 
ATOM 4680 C CE1 . PHE D 4 36  ? 100.513 125.320 90.815  1.00 70.04  ? 36  PHE R CE1 1 
ATOM 4681 C CE2 . PHE D 4 36  ? 101.975 124.782 89.013  1.00 67.68  ? 36  PHE R CE2 1 
ATOM 4682 C CZ  . PHE D 4 36  ? 101.675 125.552 90.114  1.00 69.77  ? 36  PHE R CZ  1 
ATOM 4683 N N   . PRO D 4 37  ? 97.694  121.204 91.417  1.00 62.17  ? 37  PRO R N   1 
ATOM 4684 C CA  . PRO D 4 37  ? 97.410  121.196 92.861  1.00 66.48  ? 37  PRO R CA  1 
ATOM 4685 C C   . PRO D 4 37  ? 97.787  119.894 93.539  1.00 69.75  ? 37  PRO R C   1 
ATOM 4686 O O   . PRO D 4 37  ? 98.223  119.903 94.698  1.00 75.14  ? 37  PRO R O   1 
ATOM 4687 C CB  . PRO D 4 37  ? 95.898  121.455 92.922  1.00 68.93  ? 37  PRO R CB  1 
ATOM 4688 C CG  . PRO D 4 37  ? 95.532  121.970 91.575  1.00 66.51  ? 37  PRO R CG  1 
ATOM 4689 C CD  . PRO D 4 37  ? 96.450  121.284 90.639  1.00 61.16  ? 37  PRO R CD  1 
ATOM 4690 N N   . ALA D 4 38  ? 97.633  118.767 92.843  1.00 60.86  ? 38  ALA R N   1 
ATOM 4691 C CA  . ALA D 4 38  ? 98.004  117.486 93.427  1.00 62.86  ? 38  ALA R CA  1 
ATOM 4692 C C   . ALA D 4 38  ? 99.477  117.471 93.800  1.00 65.50  ? 38  ALA R C   1 
ATOM 4693 O O   . ALA D 4 38  ? 99.852  117.057 94.905  1.00 72.94  ? 38  ALA R O   1 
ATOM 4694 C CB  . ALA D 4 38  ? 97.682  116.356 92.451  1.00 65.73  ? 38  ALA R CB  1 
ATOM 4695 N N   . ASN D 4 39  ? 100.328 117.955 92.898  1.00 59.22  ? 39  ASN R N   1 
ATOM 4696 C CA  . ASN D 4 39  ? 101.755 117.961 93.176  1.00 63.84  ? 39  ASN R CA  1 
ATOM 4697 C C   . ASN D 4 39  ? 102.119 118.984 94.241  1.00 64.01  ? 39  ASN R C   1 
ATOM 4698 O O   . ASN D 4 39  ? 103.030 118.739 95.038  1.00 64.58  ? 39  ASN R O   1 
ATOM 4699 C CB  . ASN D 4 39  ? 102.533 118.210 91.890  1.00 67.43  ? 39  ASN R CB  1 
ATOM 4700 C CG  . ASN D 4 39  ? 102.670 116.962 91.050  1.00 68.50  ? 39  ASN R CG  1 
ATOM 4701 O OD1 . ASN D 4 39  ? 103.600 116.181 91.227  1.00 71.98  ? 39  ASN R OD1 1 
ATOM 4702 N ND2 . ASN D 4 39  ? 101.740 116.766 90.130  1.00 66.16  ? 39  ASN R ND2 1 
ATOM 4703 N N   . CYS D 4 40  ? 101.424 120.122 94.295  1.00 64.82  ? 40  CYS R N   1 
ATOM 4704 C CA  . CYS D 4 40  ? 101.701 121.068 95.375  1.00 63.78  ? 40  CYS R CA  1 
ATOM 4705 C C   . CYS D 4 40  ? 101.381 120.461 96.741  1.00 68.08  ? 40  CYS R C   1 
ATOM 4706 O O   . CYS D 4 40  ? 102.170 120.581 97.693  1.00 74.40  ? 40  CYS R O   1 
ATOM 4707 C CB  . CYS D 4 40  ? 100.918 122.359 95.161  1.00 63.49  ? 40  CYS R CB  1 
ATOM 4708 S SG  . CYS D 4 40  ? 101.241 123.627 96.401  1.00 83.75  ? 40  CYS R SG  1 
ATOM 4709 N N   . LEU D 4 41  ? 100.233 119.789 96.853  1.00 50.62  ? 41  LEU R N   1 
ATOM 4710 C CA  . LEU D 4 41  ? 99.893  119.139 98.114  1.00 50.79  ? 41  LEU R CA  1 
ATOM 4711 C C   . LEU D 4 41  ? 100.875 118.021 98.446  1.00 57.76  ? 41  LEU R C   1 
ATOM 4712 O O   . LEU D 4 41  ? 101.226 117.818 99.618  1.00 64.94  ? 41  LEU R O   1 
ATOM 4713 C CB  . LEU D 4 41  ? 98.462  118.613 98.076  1.00 51.19  ? 41  LEU R CB  1 
ATOM 4714 C CG  . LEU D 4 41  ? 97.320  119.576 98.408  1.00 56.01  ? 41  LEU R CG  1 
ATOM 4715 C CD1 . LEU D 4 41  ? 97.440  120.034 99.850  1.00 60.00  ? 41  LEU R CD1 1 
ATOM 4716 C CD2 . LEU D 4 41  ? 97.260  120.771 97.483  1.00 57.57  ? 41  LEU R CD2 1 
ATOM 4717 N N   . SER D 4 42  ? 101.334 117.285 97.433  1.00 56.40  ? 42  SER R N   1 
ATOM 4718 C CA  . SER D 4 42  ? 102.339 116.260 97.690  1.00 57.77  ? 42  SER R CA  1 
ATOM 4719 C C   . SER D 4 42  ? 103.635 116.876 98.201  1.00 57.77  ? 42  SER R C   1 
ATOM 4720 O O   . SER D 4 42  ? 104.313 116.292 99.054  1.00 65.99  ? 42  SER R O   1 
ATOM 4721 C CB  . SER D 4 42  ? 102.600 115.439 96.432  1.00 60.15  ? 42  SER R CB  1 
ATOM 4722 O OG  . SER D 4 42  ? 103.687 114.556 96.636  1.00 60.94  ? 42  SER R OG  1 
ATOM 4723 N N   . LEU D 4 43  ? 104.001 118.050 97.685  1.00 51.14  ? 43  LEU R N   1 
ATOM 4724 C CA  . LEU D 4 43  ? 105.186 118.737 98.189  1.00 51.83  ? 43  LEU R CA  1 
ATOM 4725 C C   . LEU D 4 43  ? 105.020 119.115 99.651  1.00 45.34  ? 43  LEU R C   1 
ATOM 4726 O O   . LEU D 4 43  ? 105.962 118.999 100.445 1.00 52.39  ? 43  LEU R O   1 
ATOM 4727 C CB  . LEU D 4 43  ? 105.476 119.981 97.355  1.00 61.61  ? 43  LEU R CB  1 
ATOM 4728 C CG  . LEU D 4 43  ? 106.869 120.587 97.527  1.00 60.67  ? 43  LEU R CG  1 
ATOM 4729 C CD1 . LEU D 4 43  ? 107.892 119.846 96.690  1.00 54.78  ? 43  LEU R CD1 1 
ATOM 4730 C CD2 . LEU D 4 43  ? 106.856 122.067 97.175  1.00 62.18  ? 43  LEU R CD2 1 
ATOM 4731 N N   . TYR D 4 44  ? 103.832 119.586 100.023 1.00 54.06  ? 44  TYR R N   1 
ATOM 4732 C CA  . TYR D 4 44  ? 103.604 119.908 101.429 1.00 62.93  ? 44  TYR R CA  1 
ATOM 4733 C C   . TYR D 4 44  ? 103.726 118.666 102.304 1.00 67.49  ? 44  TYR R C   1 
ATOM 4734 O O   . TYR D 4 44  ? 104.313 118.714 103.395 1.00 71.04  ? 44  TYR R O   1 
ATOM 4735 C CB  . TYR D 4 44  ? 102.238 120.560 101.617 1.00 62.80  ? 44  TYR R CB  1 
ATOM 4736 C CG  . TYR D 4 44  ? 101.969 120.948 103.049 1.00 63.93  ? 44  TYR R CG  1 
ATOM 4737 C CD1 . TYR D 4 44  ? 102.934 121.598 103.800 1.00 61.41  ? 44  TYR R CD1 1 
ATOM 4738 C CD2 . TYR D 4 44  ? 100.757 120.661 103.650 1.00 63.15  ? 44  TYR R CD2 1 
ATOM 4739 C CE1 . TYR D 4 44  ? 102.700 121.952 105.105 1.00 64.17  ? 44  TYR R CE1 1 
ATOM 4740 C CE2 . TYR D 4 44  ? 100.512 121.011 104.955 1.00 64.62  ? 44  TYR R CE2 1 
ATOM 4741 C CZ  . TYR D 4 44  ? 101.487 121.656 105.680 1.00 67.08  ? 44  TYR R CZ  1 
ATOM 4742 O OH  . TYR D 4 44  ? 101.245 122.009 106.988 1.00 69.75  ? 44  TYR R OH  1 
ATOM 4743 N N   . PHE D 4 45  ? 103.183 117.539 101.839 1.00 58.42  ? 45  PHE R N   1 
ATOM 4744 C CA  . PHE D 4 45  ? 103.309 116.299 102.600 1.00 48.70  ? 45  PHE R CA  1 
ATOM 4745 C C   . PHE D 4 45  ? 104.767 115.870 102.720 1.00 48.88  ? 45  PHE R C   1 
ATOM 4746 O O   . PHE D 4 45  ? 105.192 115.358 103.763 1.00 48.66  ? 45  PHE R O   1 
ATOM 4747 C CB  . PHE D 4 45  ? 102.475 115.199 101.951 1.00 50.42  ? 45  PHE R CB  1 
ATOM 4748 C CG  . PHE D 4 45  ? 101.001 115.348 102.173 1.00 51.91  ? 45  PHE R CG  1 
ATOM 4749 C CD1 . PHE D 4 45  ? 100.501 116.405 102.901 1.00 48.96  ? 45  PHE R CD1 1 
ATOM 4750 C CD2 . PHE D 4 45  ? 100.116 114.424 101.655 1.00 58.70  ? 45  PHE R CD2 1 
ATOM 4751 C CE1 . PHE D 4 45  ? 99.153  116.543 103.105 1.00 52.14  ? 45  PHE R CE1 1 
ATOM 4752 C CE2 . PHE D 4 45  ? 98.762  114.558 101.860 1.00 60.10  ? 45  PHE R CE2 1 
ATOM 4753 C CZ  . PHE D 4 45  ? 98.282  115.619 102.587 1.00 56.23  ? 45  PHE R CZ  1 
ATOM 4754 N N   . GLY D 4 46  ? 105.546 116.064 101.658 1.00 53.14  ? 46  GLY R N   1 
ATOM 4755 C CA  . GLY D 4 46  ? 106.961 115.743 101.722 1.00 49.60  ? 46  GLY R CA  1 
ATOM 4756 C C   . GLY D 4 46  ? 107.709 116.606 102.717 1.00 52.13  ? 46  GLY R C   1 
ATOM 4757 O O   . GLY D 4 46  ? 108.611 116.131 103.409 1.00 57.12  ? 46  GLY R O   1 
ATOM 4758 N N   . TYR D 4 47  ? 107.359 117.891 102.787 1.00 60.16  ? 47  TYR R N   1 
ATOM 4759 C CA  . TYR D 4 47  ? 107.886 118.748 103.846 1.00 52.76  ? 47  TYR R CA  1 
ATOM 4760 C C   . TYR D 4 47  ? 107.557 118.177 105.215 1.00 55.18  ? 47  TYR R C   1 
ATOM 4761 O O   . TYR D 4 47  ? 108.431 118.062 106.086 1.00 60.65  ? 47  TYR R O   1 
ATOM 4762 C CB  . TYR D 4 47  ? 107.311 120.157 103.716 1.00 56.86  ? 47  TYR R CB  1 
ATOM 4763 C CG  . TYR D 4 47  ? 107.851 121.163 104.710 1.00 55.74  ? 47  TYR R CG  1 
ATOM 4764 C CD1 . TYR D 4 47  ? 109.050 120.955 105.367 1.00 53.49  ? 47  TYR R CD1 1 
ATOM 4765 C CD2 . TYR D 4 47  ? 107.140 122.315 105.003 1.00 60.51  ? 47  TYR R CD2 1 
ATOM 4766 C CE1 . TYR D 4 47  ? 109.531 121.866 106.276 1.00 57.77  ? 47  TYR R CE1 1 
ATOM 4767 C CE2 . TYR D 4 47  ? 107.613 123.233 105.910 1.00 63.78  ? 47  TYR R CE2 1 
ATOM 4768 C CZ  . TYR D 4 47  ? 108.810 123.004 106.544 1.00 65.40  ? 47  TYR R CZ  1 
ATOM 4769 O OH  . TYR D 4 47  ? 109.290 123.919 107.453 1.00 63.30  ? 47  TYR R OH  1 
ATOM 4770 N N   . LEU D 4 48  ? 106.293 117.811 105.421 1.00 58.71  ? 48  LEU R N   1 
ATOM 4771 C CA  . LEU D 4 48  ? 105.886 117.287 106.720 1.00 59.55  ? 48  LEU R CA  1 
ATOM 4772 C C   . LEU D 4 48  ? 106.690 116.048 107.084 1.00 60.77  ? 48  LEU R C   1 
ATOM 4773 O O   . LEU D 4 48  ? 107.066 115.862 108.246 1.00 60.59  ? 48  LEU R O   1 
ATOM 4774 C CB  . LEU D 4 48  ? 104.393 116.979 106.718 1.00 61.55  ? 48  LEU R CB  1 
ATOM 4775 C CG  . LEU D 4 48  ? 103.510 118.067 107.321 1.00 65.32  ? 48  LEU R CG  1 
ATOM 4776 C CD1 . LEU D 4 48  ? 102.053 117.639 107.317 1.00 62.64  ? 48  LEU R CD1 1 
ATOM 4777 C CD2 . LEU D 4 48  ? 103.971 118.400 108.727 1.00 63.81  ? 48  LEU R CD2 1 
ATOM 4778 N N   . GLN D 4 49  ? 106.964 115.190 106.102 1.00 63.72  ? 49  GLN R N   1 
ATOM 4779 C CA  . GLN D 4 49  ? 107.734 113.980 106.377 1.00 54.89  ? 49  GLN R CA  1 
ATOM 4780 C C   . GLN D 4 49  ? 109.194 114.303 106.668 1.00 50.45  ? 49  GLN R C   1 
ATOM 4781 O O   . GLN D 4 49  ? 109.770 113.791 107.633 1.00 55.42  ? 49  GLN R O   1 
ATOM 4782 C CB  . GLN D 4 49  ? 107.625 113.004 105.210 1.00 54.58  ? 49  GLN R CB  1 
ATOM 4783 C CG  . GLN D 4 49  ? 106.232 112.467 104.991 1.00 58.15  ? 49  GLN R CG  1 
ATOM 4784 C CD  . GLN D 4 49  ? 105.734 111.673 106.171 1.00 58.29  ? 49  GLN R CD  1 
ATOM 4785 O OE1 . GLN D 4 49  ? 104.842 112.110 106.895 1.00 57.54  ? 49  GLN R OE1 1 
ATOM 4786 N NE2 . GLN D 4 49  ? 106.313 110.500 106.381 1.00 60.50  ? 49  GLN R NE2 1 
ATOM 4787 N N   . ILE D 4 50  ? 109.813 115.150 105.843 1.00 55.38  ? 50  ILE R N   1 
ATOM 4788 C CA  . ILE D 4 50  ? 111.239 115.417 106.002 1.00 53.46  ? 50  ILE R CA  1 
ATOM 4789 C C   . ILE D 4 50  ? 111.509 116.141 107.310 1.00 54.76  ? 50  ILE R C   1 
ATOM 4790 O O   . ILE D 4 50  ? 112.607 116.039 107.866 1.00 56.81  ? 50  ILE R O   1 
ATOM 4791 C CB  . ILE D 4 50  ? 111.784 116.202 104.794 1.00 59.76  ? 50  ILE R CB  1 
ATOM 4792 C CG1 . ILE D 4 50  ? 113.306 116.257 104.833 1.00 58.50  ? 50  ILE R CG1 1 
ATOM 4793 C CG2 . ILE D 4 50  ? 111.237 117.610 104.764 1.00 60.64  ? 50  ILE R CG2 1 
ATOM 4794 C CD1 . ILE D 4 50  ? 113.923 116.722 103.537 1.00 56.84  ? 50  ILE R CD1 1 
ATOM 4795 N N   . LYS D 4 51  ? 110.526 116.879 107.828 1.00 65.12  ? 51  LYS R N   1 
ATOM 4796 C CA  . LYS D 4 51  ? 110.724 117.535 109.115 1.00 63.29  ? 51  LYS R CA  1 
ATOM 4797 C C   . LYS D 4 51  ? 110.948 116.517 110.225 1.00 60.01  ? 51  LYS R C   1 
ATOM 4798 O O   . LYS D 4 51  ? 111.827 116.698 111.075 1.00 63.11  ? 51  LYS R O   1 
ATOM 4799 C CB  . LYS D 4 51  ? 109.529 118.431 109.440 1.00 62.35  ? 51  LYS R CB  1 
ATOM 4800 N N   . ALA D 4 52  ? 110.171 115.439 110.235 1.00 60.63  ? 52  ALA R N   1 
ATOM 4801 C CA  . ALA D 4 52  ? 110.226 114.467 111.325 1.00 65.15  ? 52  ALA R CA  1 
ATOM 4802 C C   . ALA D 4 52  ? 111.172 113.306 111.028 1.00 67.84  ? 52  ALA R C   1 
ATOM 4803 O O   . ALA D 4 52  ? 110.813 112.142 111.193 1.00 71.87  ? 52  ALA R O   1 
ATOM 4804 C CB  . ALA D 4 52  ? 108.823 113.960 111.631 1.00 68.47  ? 52  ALA R CB  1 
ATOM 4805 N N   . ARG D 4 53  ? 112.391 113.630 110.610 1.00 68.52  ? 53  ARG R N   1 
ATOM 4806 C CA  . ARG D 4 53  ? 113.501 112.682 110.488 1.00 67.11  ? 53  ARG R CA  1 
ATOM 4807 C C   . ARG D 4 53  ? 113.081 111.377 109.811 1.00 66.82  ? 53  ARG R C   1 
ATOM 4808 O O   . ARG D 4 53  ? 113.133 110.294 110.393 1.00 71.56  ? 53  ARG R O   1 
ATOM 4809 C CB  . ARG D 4 53  ? 114.121 112.406 111.855 1.00 68.05  ? 53  ARG R CB  1 
ATOM 4810 N N   . ASN D 4 54  ? 112.656 111.498 108.557 1.00 58.22  ? 54  ASN R N   1 
ATOM 4811 C CA  . ASN D 4 54  ? 112.313 110.344 107.738 1.00 59.01  ? 54  ASN R CA  1 
ATOM 4812 C C   . ASN D 4 54  ? 113.109 110.411 106.446 1.00 60.87  ? 54  ASN R C   1 
ATOM 4813 O O   . ASN D 4 54  ? 113.209 111.477 105.831 1.00 64.61  ? 54  ASN R O   1 
ATOM 4814 C CB  . ASN D 4 54  ? 110.814 110.297 107.441 1.00 59.63  ? 54  ASN R CB  1 
ATOM 4815 C CG  . ASN D 4 54  ? 110.338 108.910 107.081 1.00 60.01  ? 54  ASN R CG  1 
ATOM 4816 O OD1 . ASN D 4 54  ? 111.123 107.966 107.033 1.00 68.97  ? 54  ASN R OD1 1 
ATOM 4817 N ND2 . ASN D 4 54  ? 109.047 108.778 106.824 1.00 56.95  ? 54  ASN R ND2 1 
ATOM 4818 N N   . GLU D 4 55  ? 113.675 109.277 106.037 1.00 54.11  ? 55  GLU R N   1 
ATOM 4819 C CA  . GLU D 4 55  ? 114.560 109.278 104.880 1.00 50.32  ? 55  GLU R CA  1 
ATOM 4820 C C   . GLU D 4 55  ? 113.794 109.394 103.570 1.00 53.76  ? 55  GLU R C   1 
ATOM 4821 O O   . GLU D 4 55  ? 114.332 109.929 102.595 1.00 62.47  ? 55  GLU R O   1 
ATOM 4822 C CB  . GLU D 4 55  ? 115.425 108.019 104.878 1.00 50.14  ? 55  GLU R CB  1 
ATOM 4823 N N   . LEU D 4 56  ? 112.555 108.898 103.512 1.00 48.49  ? 56  LEU R N   1 
ATOM 4824 C CA  . LEU D 4 56  ? 111.800 109.002 102.268 1.00 55.54  ? 56  LEU R CA  1 
ATOM 4825 C C   . LEU D 4 56  ? 111.494 110.439 101.883 1.00 64.65  ? 56  LEU R C   1 
ATOM 4826 O O   . LEU D 4 56  ? 111.338 110.717 100.691 1.00 63.77  ? 56  LEU R O   1 
ATOM 4827 C CB  . LEU D 4 56  ? 110.483 108.230 102.334 1.00 48.86  ? 56  LEU R CB  1 
ATOM 4828 C CG  . LEU D 4 56  ? 110.473 106.716 102.431 1.00 52.86  ? 56  LEU R CG  1 
ATOM 4829 C CD1 . LEU D 4 56  ? 109.050 106.246 102.612 1.00 50.74  ? 56  LEU R CD1 1 
ATOM 4830 C CD2 . LEU D 4 56  ? 111.071 106.122 101.177 1.00 56.63  ? 56  LEU R CD2 1 
ATOM 4831 N N   . GLY D 4 57  ? 111.430 111.352 102.851 1.00 63.54  ? 57  GLY R N   1 
ATOM 4832 C CA  . GLY D 4 57  ? 111.002 112.705 102.547 1.00 58.40  ? 57  GLY R CA  1 
ATOM 4833 C C   . GLY D 4 57  ? 111.836 113.350 101.461 1.00 54.82  ? 57  GLY R C   1 
ATOM 4834 O O   . GLY D 4 57  ? 111.311 114.071 100.609 1.00 62.74  ? 57  GLY R O   1 
ATOM 4835 N N   . VAL D 4 58  ? 113.141 113.082 101.461 1.00 46.00  ? 58  VAL R N   1 
ATOM 4836 C CA  . VAL D 4 58  ? 114.007 113.618 100.418 1.00 56.73  ? 58  VAL R CA  1 
ATOM 4837 C C   . VAL D 4 58  ? 113.562 113.114 99.051  1.00 61.15  ? 58  VAL R C   1 
ATOM 4838 O O   . VAL D 4 58  ? 113.434 113.886 98.091  1.00 63.24  ? 58  VAL R O   1 
ATOM 4839 C CB  . VAL D 4 58  ? 115.471 113.252 100.703 1.00 53.51  ? 58  VAL R CB  1 
ATOM 4840 C CG1 . VAL D 4 58  ? 116.389 113.978 99.744  1.00 53.17  ? 58  VAL R CG1 1 
ATOM 4841 C CG2 . VAL D 4 58  ? 115.817 113.585 102.132 1.00 52.46  ? 58  VAL R CG2 1 
ATOM 4842 N N   . TYR D 4 59  ? 113.302 111.808 98.950  1.00 56.82  ? 59  TYR R N   1 
ATOM 4843 C CA  . TYR D 4 59  ? 112.912 111.224 97.674  1.00 48.02  ? 59  TYR R CA  1 
ATOM 4844 C C   . TYR D 4 59  ? 111.556 111.740 97.211  1.00 50.38  ? 59  TYR R C   1 
ATOM 4845 O O   . TYR D 4 59  ? 111.387 112.073 96.032  1.00 62.57  ? 59  TYR R O   1 
ATOM 4846 C CB  . TYR D 4 59  ? 112.906 109.705 97.780  1.00 47.73  ? 59  TYR R CB  1 
ATOM 4847 C CG  . TYR D 4 59  ? 114.217 109.123 98.244  1.00 50.48  ? 59  TYR R CG  1 
ATOM 4848 C CD1 . TYR D 4 59  ? 115.386 109.370 97.553  1.00 54.67  ? 59  TYR R CD1 1 
ATOM 4849 C CD2 . TYR D 4 59  ? 114.282 108.319 99.365  1.00 52.27  ? 59  TYR R CD2 1 
ATOM 4850 C CE1 . TYR D 4 59  ? 116.582 108.838 97.967  1.00 54.89  ? 59  TYR R CE1 1 
ATOM 4851 C CE2 . TYR D 4 59  ? 115.477 107.783 99.785  1.00 52.88  ? 59  TYR R CE2 1 
ATOM 4852 C CZ  . TYR D 4 59  ? 116.622 108.046 99.082  1.00 53.46  ? 59  TYR R CZ  1 
ATOM 4853 O OH  . TYR D 4 59  ? 117.817 107.515 99.494  1.00 55.06  ? 59  TYR R OH  1 
ATOM 4854 N N   . LEU D 4 60  ? 110.580 111.814 98.117  1.00 47.24  ? 60  LEU R N   1 
ATOM 4855 C CA  . LEU D 4 60  ? 109.276 112.349 97.739  1.00 52.33  ? 60  LEU R CA  1 
ATOM 4856 C C   . LEU D 4 60  ? 109.376 113.798 97.280  1.00 59.77  ? 60  LEU R C   1 
ATOM 4857 O O   . LEU D 4 60  ? 108.768 114.177 96.271  1.00 63.85  ? 60  LEU R O   1 
ATOM 4858 C CB  . LEU D 4 60  ? 108.279 112.217 98.891  1.00 50.18  ? 60  LEU R CB  1 
ATOM 4859 C CG  . LEU D 4 60  ? 107.620 110.861 99.157  1.00 53.07  ? 60  LEU R CG  1 
ATOM 4860 C CD1 . LEU D 4 60  ? 108.566 109.840 99.733  1.00 53.94  ? 60  LEU R CD1 1 
ATOM 4861 C CD2 . LEU D 4 60  ? 106.426 111.043 100.072 1.00 58.96  ? 60  LEU R CD2 1 
ATOM 4862 N N   . CYS D 4 61  ? 110.139 114.624 97.999  1.00 54.37  ? 61  CYS R N   1 
ATOM 4863 C CA  . CYS D 4 61  ? 110.263 116.022 97.610  1.00 49.71  ? 61  CYS R CA  1 
ATOM 4864 C C   . CYS D 4 61  ? 110.928 116.157 96.249  1.00 51.64  ? 61  CYS R C   1 
ATOM 4865 O O   . CYS D 4 61  ? 110.477 116.942 95.404  1.00 62.32  ? 61  CYS R O   1 
ATOM 4866 C CB  . CYS D 4 61  ? 111.042 116.796 98.669  1.00 53.57  ? 61  CYS R CB  1 
ATOM 4867 S SG  . CYS D 4 61  ? 110.102 117.168 100.153 1.00 70.95  ? 61  CYS R SG  1 
ATOM 4868 N N   . ASN D 4 62  ? 111.993 115.392 96.009  1.00 38.29  ? 62  ASN R N   1 
ATOM 4869 C CA  . ASN D 4 62  ? 112.675 115.485 94.724  1.00 46.97  ? 62  ASN R CA  1 
ATOM 4870 C C   . ASN D 4 62  ? 111.787 114.997 93.584  1.00 56.90  ? 62  ASN R C   1 
ATOM 4871 O O   . ASN D 4 62  ? 111.770 115.598 92.501  1.00 61.97  ? 62  ASN R O   1 
ATOM 4872 C CB  . ASN D 4 62  ? 113.978 114.700 94.774  1.00 51.99  ? 62  ASN R CB  1 
ATOM 4873 C CG  . ASN D 4 62  ? 115.062 115.429 95.522  1.00 57.63  ? 62  ASN R CG  1 
ATOM 4874 O OD1 . ASN D 4 62  ? 115.783 114.838 96.323  1.00 63.57  ? 62  ASN R OD1 1 
ATOM 4875 N ND2 . ASN D 4 62  ? 115.188 116.724 95.267  1.00 56.31  ? 62  ASN R ND2 1 
ATOM 4876 N N   . LEU D 4 63  ? 111.041 113.914 93.809  1.00 45.98  ? 63  LEU R N   1 
ATOM 4877 C CA  . LEU D 4 63  ? 110.133 113.410 92.785  1.00 45.72  ? 63  LEU R CA  1 
ATOM 4878 C C   . LEU D 4 63  ? 109.049 114.427 92.465  1.00 51.41  ? 63  LEU R C   1 
ATOM 4879 O O   . LEU D 4 63  ? 108.708 114.639 91.294  1.00 57.28  ? 63  LEU R O   1 
ATOM 4880 C CB  . LEU D 4 63  ? 109.522 112.091 93.250  1.00 44.78  ? 63  LEU R CB  1 
ATOM 4881 C CG  . LEU D 4 63  ? 108.517 111.377 92.359  1.00 45.17  ? 63  LEU R CG  1 
ATOM 4882 C CD1 . LEU D 4 63  ? 109.197 110.866 91.118  1.00 50.76  ? 63  LEU R CD1 1 
ATOM 4883 C CD2 . LEU D 4 63  ? 107.898 110.237 93.123  1.00 51.20  ? 63  LEU R CD2 1 
ATOM 4884 N N   . THR D 4 64  ? 108.503 115.076 93.492  1.00 42.61  ? 64  THR R N   1 
ATOM 4885 C CA  . THR D 4 64  ? 107.486 116.094 93.263  1.00 42.21  ? 64  THR R CA  1 
ATOM 4886 C C   . THR D 4 64  ? 108.055 117.289 92.508  1.00 47.73  ? 64  THR R C   1 
ATOM 4887 O O   . THR D 4 64  ? 107.384 117.857 91.638  1.00 54.73  ? 64  THR R O   1 
ATOM 4888 C CB  . THR D 4 64  ? 106.883 116.528 94.593  1.00 50.16  ? 64  THR R CB  1 
ATOM 4889 O OG1 . THR D 4 64  ? 106.281 115.398 95.232  1.00 52.51  ? 64  THR R OG1 1 
ATOM 4890 C CG2 . THR D 4 64  ? 105.837 117.598 94.379  1.00 52.40  ? 64  THR R CG2 1 
ATOM 4891 N N   . VAL D 4 65  ? 109.289 117.684 92.819  1.00 47.45  ? 65  VAL R N   1 
ATOM 4892 C CA  . VAL D 4 65  ? 109.906 118.792 92.097  1.00 43.01  ? 65  VAL R CA  1 
ATOM 4893 C C   . VAL D 4 65  ? 110.114 118.431 90.632  1.00 46.01  ? 65  VAL R C   1 
ATOM 4894 O O   . VAL D 4 65  ? 109.879 119.253 89.736  1.00 49.89  ? 65  VAL R O   1 
ATOM 4895 C CB  . VAL D 4 65  ? 111.222 119.204 92.775  1.00 43.95  ? 65  VAL R CB  1 
ATOM 4896 C CG1 . VAL D 4 65  ? 112.027 120.104 91.862  1.00 48.72  ? 65  VAL R CG1 1 
ATOM 4897 C CG2 . VAL D 4 65  ? 110.935 119.903 94.089  1.00 49.81  ? 65  VAL R CG2 1 
ATOM 4898 N N   . ALA D 4 66  ? 110.548 117.199 90.359  1.00 53.78  ? 66  ALA R N   1 
ATOM 4899 C CA  . ALA D 4 66  ? 110.705 116.768 88.972  1.00 57.08  ? 66  ALA R CA  1 
ATOM 4900 C C   . ALA D 4 66  ? 109.367 116.764 88.239  1.00 59.47  ? 66  ALA R C   1 
ATOM 4901 O O   . ALA D 4 66  ? 109.282 117.176 87.073  1.00 60.30  ? 66  ALA R O   1 
ATOM 4902 C CB  . ALA D 4 66  ? 111.349 115.385 88.919  1.00 59.60  ? 66  ALA R CB  1 
ATOM 4903 N N   . ASP D 4 67  ? 108.309 116.307 88.910  1.00 59.94  ? 67  ASP R N   1 
ATOM 4904 C CA  . ASP D 4 67  ? 106.985 116.332 88.300  1.00 59.11  ? 67  ASP R CA  1 
ATOM 4905 C C   . ASP D 4 67  ? 106.536 117.757 87.996  1.00 64.87  ? 67  ASP R C   1 
ATOM 4906 O O   . ASP D 4 67  ? 105.958 118.015 86.935  1.00 68.36  ? 67  ASP R O   1 
ATOM 4907 C CB  . ASP D 4 67  ? 105.974 115.639 89.210  1.00 60.71  ? 67  ASP R CB  1 
ATOM 4908 C CG  . ASP D 4 67  ? 106.157 114.142 89.249  1.00 67.73  ? 67  ASP R CG  1 
ATOM 4909 O OD1 . ASP D 4 67  ? 106.674 113.580 88.263  1.00 74.21  ? 67  ASP R OD1 1 
ATOM 4910 O OD2 . ASP D 4 67  ? 105.781 113.525 90.266  1.00 63.86  ? 67  ASP R OD2 1 
ATOM 4911 N N   . LEU D 4 68  ? 106.774 118.693 88.918  1.00 59.68  ? 68  LEU R N   1 
ATOM 4912 C CA  . LEU D 4 68  ? 106.429 120.088 88.651  1.00 48.75  ? 68  LEU R CA  1 
ATOM 4913 C C   . LEU D 4 68  ? 107.217 120.637 87.474  1.00 47.33  ? 68  LEU R C   1 
ATOM 4914 O O   . LEU D 4 68  ? 106.685 121.409 86.668  1.00 59.33  ? 68  LEU R O   1 
ATOM 4915 C CB  . LEU D 4 68  ? 106.669 120.956 89.883  1.00 48.70  ? 68  LEU R CB  1 
ATOM 4916 C CG  . LEU D 4 68  ? 105.806 120.737 91.114  1.00 50.55  ? 68  LEU R CG  1 
ATOM 4917 C CD1 . LEU D 4 68  ? 106.311 121.595 92.252  1.00 54.11  ? 68  LEU R CD1 1 
ATOM 4918 C CD2 . LEU D 4 68  ? 104.388 121.104 90.783  1.00 59.68  ? 68  LEU R CD2 1 
ATOM 4919 N N   . PHE D 4 69  ? 108.496 120.278 87.374  1.00 54.88  ? 69  PHE R N   1 
ATOM 4920 C CA  . PHE D 4 69  ? 109.295 120.749 86.251  1.00 53.39  ? 69  PHE R CA  1 
ATOM 4921 C C   . PHE D 4 69  ? 108.738 120.224 84.937  1.00 58.94  ? 69  PHE R C   1 
ATOM 4922 O O   . PHE D 4 69  ? 108.685 120.951 83.940  1.00 61.44  ? 69  PHE R O   1 
ATOM 4923 C CB  . PHE D 4 69  ? 110.749 120.327 86.431  1.00 59.96  ? 69  PHE R CB  1 
ATOM 4924 C CG  . PHE D 4 69  ? 111.563 121.298 87.229  1.00 62.67  ? 69  PHE R CG  1 
ATOM 4925 C CD1 . PHE D 4 69  ? 110.948 122.280 87.979  1.00 64.00  ? 69  PHE R CD1 1 
ATOM 4926 C CD2 . PHE D 4 69  ? 112.942 121.222 87.239  1.00 60.52  ? 69  PHE R CD2 1 
ATOM 4927 C CE1 . PHE D 4 69  ? 111.690 123.171 88.717  1.00 64.52  ? 69  PHE R CE1 1 
ATOM 4928 C CE2 . PHE D 4 69  ? 113.690 122.112 87.978  1.00 61.87  ? 69  PHE R CE2 1 
ATOM 4929 C CZ  . PHE D 4 69  ? 113.063 123.088 88.717  1.00 65.20  ? 69  PHE R CZ  1 
ATOM 4930 N N   . TYR D 4 70  ? 108.305 118.965 84.921  1.00 64.99  ? 70  TYR R N   1 
ATOM 4931 C CA  . TYR D 4 70  ? 107.656 118.425 83.730  1.00 60.36  ? 70  TYR R CA  1 
ATOM 4932 C C   . TYR D 4 70  ? 106.369 119.178 83.426  1.00 57.61  ? 70  TYR R C   1 
ATOM 4933 O O   . TYR D 4 70  ? 106.113 119.556 82.279  1.00 62.15  ? 70  TYR R O   1 
ATOM 4934 C CB  . TYR D 4 70  ? 107.367 116.939 83.926  1.00 61.64  ? 70  TYR R CB  1 
ATOM 4935 C CG  . TYR D 4 70  ? 106.808 116.229 82.714  1.00 61.46  ? 70  TYR R CG  1 
ATOM 4936 C CD1 . TYR D 4 70  ? 107.648 115.666 81.772  1.00 65.13  ? 70  TYR R CD1 1 
ATOM 4937 C CD2 . TYR D 4 70  ? 105.448 116.120 82.514  1.00 59.57  ? 70  TYR R CD2 1 
ATOM 4938 C CE1 . TYR D 4 70  ? 107.148 115.012 80.673  1.00 66.44  ? 70  TYR R CE1 1 
ATOM 4939 C CE2 . TYR D 4 70  ? 104.942 115.468 81.421  1.00 61.80  ? 70  TYR R CE2 1 
ATOM 4940 C CZ  . TYR D 4 70  ? 105.795 114.919 80.503  1.00 64.16  ? 70  TYR R CZ  1 
ATOM 4941 O OH  . TYR D 4 70  ? 105.285 114.269 79.408  1.00 65.91  ? 70  TYR R OH  1 
ATOM 4942 N N   . ILE D 4 71  ? 105.557 119.424 84.456  1.00 56.88  ? 71  ILE R N   1 
ATOM 4943 C CA  . ILE D 4 71  ? 104.234 120.015 84.264  1.00 54.92  ? 71  ILE R CA  1 
ATOM 4944 C C   . ILE D 4 71  ? 104.350 121.432 83.722  1.00 60.53  ? 71  ILE R C   1 
ATOM 4945 O O   . ILE D 4 71  ? 103.590 121.837 82.834  1.00 64.28  ? 71  ILE R O   1 
ATOM 4946 C CB  . ILE D 4 71  ? 103.439 119.976 85.580  1.00 52.94  ? 71  ILE R CB  1 
ATOM 4947 C CG1 . ILE D 4 71  ? 102.863 118.586 85.813  1.00 61.15  ? 71  ILE R CG1 1 
ATOM 4948 C CG2 . ILE D 4 71  ? 102.318 120.977 85.551  1.00 58.30  ? 71  ILE R CG2 1 
ATOM 4949 C CD1 . ILE D 4 71  ? 102.144 118.444 87.128  1.00 65.15  ? 71  ILE R CD1 1 
ATOM 4950 N N   . CYS D 4 72  ? 105.309 122.204 84.235  1.00 61.12  ? 72  CYS R N   1 
ATOM 4951 C CA  . CYS D 4 72  ? 105.470 123.585 83.796  1.00 60.70  ? 72  CYS R CA  1 
ATOM 4952 C C   . CYS D 4 72  ? 105.804 123.693 82.316  1.00 62.32  ? 72  CYS R C   1 
ATOM 4953 O O   . CYS D 4 72  ? 105.653 124.774 81.737  1.00 68.65  ? 72  CYS R O   1 
ATOM 4954 C CB  . CYS D 4 72  ? 106.550 124.284 84.619  1.00 62.21  ? 72  CYS R CB  1 
ATOM 4955 S SG  . CYS D 4 72  ? 106.140 124.488 86.361  1.00 78.05  ? 72  CYS R SG  1 
ATOM 4956 N N   . SER D 4 73  ? 106.253 122.612 81.690  1.00 57.29  ? 73  SER R N   1 
ATOM 4957 C CA  . SER D 4 73  ? 106.609 122.659 80.282  1.00 58.77  ? 73  SER R CA  1 
ATOM 4958 C C   . SER D 4 73  ? 105.428 122.437 79.353  1.00 64.29  ? 73  SER R C   1 
ATOM 4959 O O   . SER D 4 73  ? 105.518 122.787 78.171  1.00 67.16  ? 73  SER R O   1 
ATOM 4960 C CB  . SER D 4 73  ? 107.687 121.617 79.977  1.00 66.36  ? 73  SER R CB  1 
ATOM 4961 O OG  . SER D 4 73  ? 107.123 120.324 79.847  1.00 69.79  ? 73  SER R OG  1 
ATOM 4962 N N   . LEU D 4 74  ? 104.334 121.861 79.847  1.00 62.92  ? 74  LEU R N   1 
ATOM 4963 C CA  . LEU D 4 74  ? 103.186 121.604 78.983  1.00 63.76  ? 74  LEU R CA  1 
ATOM 4964 C C   . LEU D 4 74  ? 102.585 122.854 78.349  1.00 62.56  ? 74  LEU R C   1 
ATOM 4965 O O   . LEU D 4 74  ? 102.218 122.783 77.164  1.00 70.10  ? 74  LEU R O   1 
ATOM 4966 C CB  . LEU D 4 74  ? 102.110 120.814 79.740  1.00 62.82  ? 74  LEU R CB  1 
ATOM 4967 C CG  . LEU D 4 74  ? 102.304 119.304 79.920  1.00 66.73  ? 74  LEU R CG  1 
ATOM 4968 C CD1 . LEU D 4 74  ? 103.397 118.970 80.904  1.00 66.53  ? 74  LEU R CD1 1 
ATOM 4969 C CD2 . LEU D 4 74  ? 100.999 118.642 80.328  1.00 67.00  ? 74  LEU R CD2 1 
ATOM 4970 N N   . PRO D 4 75  ? 102.429 123.989 79.043  1.00 52.35  ? 75  PRO R N   1 
ATOM 4971 C CA  . PRO D 4 75  ? 101.801 125.147 78.386  1.00 54.84  ? 75  PRO R CA  1 
ATOM 4972 C C   . PRO D 4 75  ? 102.449 125.555 77.075  1.00 56.23  ? 75  PRO R C   1 
ATOM 4973 O O   . PRO D 4 75  ? 101.735 125.913 76.132  1.00 65.35  ? 75  PRO R O   1 
ATOM 4974 C CB  . PRO D 4 75  ? 101.926 126.242 79.448  1.00 57.10  ? 75  PRO R CB  1 
ATOM 4975 C CG  . PRO D 4 75  ? 101.876 125.510 80.711  1.00 61.18  ? 75  PRO R CG  1 
ATOM 4976 C CD  . PRO D 4 75  ? 102.617 124.235 80.482  1.00 59.01  ? 75  PRO R CD  1 
ATOM 4977 N N   . PHE D 4 76  ? 103.776 125.505 76.977  1.00 61.95  ? 76  PHE R N   1 
ATOM 4978 C CA  . PHE D 4 76  ? 104.412 125.788 75.696  1.00 67.71  ? 76  PHE R CA  1 
ATOM 4979 C C   . PHE D 4 76  ? 104.055 124.728 74.661  1.00 75.11  ? 76  PHE R C   1 
ATOM 4980 O O   . PHE D 4 76  ? 103.734 125.053 73.511  1.00 76.95  ? 76  PHE R O   1 
ATOM 4981 C CB  . PHE D 4 76  ? 105.923 125.895 75.871  1.00 69.71  ? 76  PHE R CB  1 
ATOM 4982 C CG  . PHE D 4 76  ? 106.352 127.067 76.697  1.00 73.35  ? 76  PHE R CG  1 
ATOM 4983 C CD1 . PHE D 4 76  ? 106.044 128.354 76.301  1.00 72.20  ? 76  PHE R CD1 1 
ATOM 4984 C CD2 . PHE D 4 76  ? 107.063 126.885 77.867  1.00 71.86  ? 76  PHE R CD2 1 
ATOM 4985 C CE1 . PHE D 4 76  ? 106.438 129.437 77.056  1.00 70.81  ? 76  PHE R CE1 1 
ATOM 4986 C CE2 . PHE D 4 76  ? 107.460 127.964 78.625  1.00 71.19  ? 76  PHE R CE2 1 
ATOM 4987 C CZ  . PHE D 4 76  ? 107.147 129.241 78.220  1.00 72.26  ? 76  PHE R CZ  1 
ATOM 4988 N N   . TRP D 4 77  ? 104.085 123.453 75.055  1.00 68.54  ? 77  TRP R N   1 
ATOM 4989 C CA  . TRP D 4 77  ? 103.628 122.402 74.154  1.00 63.33  ? 77  TRP R CA  1 
ATOM 4990 C C   . TRP D 4 77  ? 102.152 122.560 73.837  1.00 62.88  ? 77  TRP R C   1 
ATOM 4991 O O   . TRP D 4 77  ? 101.718 122.271 72.719  1.00 66.66  ? 77  TRP R O   1 
ATOM 4992 C CB  . TRP D 4 77  ? 103.895 121.023 74.755  1.00 63.14  ? 77  TRP R CB  1 
ATOM 4993 C CG  . TRP D 4 77  ? 105.322 120.620 74.730  1.00 59.59  ? 77  TRP R CG  1 
ATOM 4994 C CD1 . TRP D 4 77  ? 106.188 120.616 75.774  1.00 60.48  ? 77  TRP R CD1 1 
ATOM 4995 C CD2 . TRP D 4 77  ? 106.053 120.153 73.599  1.00 56.11  ? 77  TRP R CD2 1 
ATOM 4996 N NE1 . TRP D 4 77  ? 107.418 120.179 75.363  1.00 64.61  ? 77  TRP R NE1 1 
ATOM 4997 C CE2 . TRP D 4 77  ? 107.359 119.891 74.027  1.00 59.10  ? 77  TRP R CE2 1 
ATOM 4998 C CE3 . TRP D 4 77  ? 105.730 119.938 72.261  1.00 64.63  ? 77  TRP R CE3 1 
ATOM 4999 C CZ2 . TRP D 4 77  ? 108.341 119.421 73.169  1.00 63.23  ? 77  TRP R CZ2 1 
ATOM 5000 C CZ3 . TRP D 4 77  ? 106.700 119.475 71.415  1.00 62.06  ? 77  TRP R CZ3 1 
ATOM 5001 C CH2 . TRP D 4 77  ? 107.990 119.217 71.868  1.00 61.08  ? 77  TRP R CH2 1 
ATOM 5002 N N   . LEU D 4 78  ? 101.358 122.994 74.817  1.00 65.61  ? 78  LEU R N   1 
ATOM 5003 C CA  . LEU D 4 78  ? 99.937  123.198 74.565  1.00 61.38  ? 78  LEU R CA  1 
ATOM 5004 C C   . LEU D 4 78  ? 99.724  124.258 73.498  1.00 67.51  ? 78  LEU R C   1 
ATOM 5005 O O   . LEU D 4 78  ? 98.890  124.088 72.603  1.00 75.93  ? 78  LEU R O   1 
ATOM 5006 C CB  . LEU D 4 78  ? 99.220  123.584 75.854  1.00 61.73  ? 78  LEU R CB  1 
ATOM 5007 C CG  . LEU D 4 78  ? 97.711  123.760 75.724  1.00 68.64  ? 78  LEU R CG  1 
ATOM 5008 C CD1 . LEU D 4 78  ? 97.060  122.450 75.315  1.00 69.37  ? 78  LEU R CD1 1 
ATOM 5009 C CD2 . LEU D 4 78  ? 97.118  124.275 77.026  1.00 66.81  ? 78  LEU R CD2 1 
ATOM 5010 N N   . GLN D 4 79  ? 100.484 125.351 73.563  1.00 79.12  ? 79  GLN R N   1 
ATOM 5011 C CA  . GLN D 4 79  ? 100.383 126.374 72.529  1.00 80.12  ? 79  GLN R CA  1 
ATOM 5012 C C   . GLN D 4 79  ? 100.915 125.868 71.197  1.00 76.50  ? 79  GLN R C   1 
ATOM 5013 O O   . GLN D 4 79  ? 100.425 126.274 70.139  1.00 77.48  ? 79  GLN R O   1 
ATOM 5014 C CB  . GLN D 4 79  ? 101.130 127.634 72.964  1.00 78.12  ? 79  GLN R CB  1 
ATOM 5015 N N   . TYR D 4 80  ? 101.912 124.985 71.230  1.00 66.23  ? 80  TYR R N   1 
ATOM 5016 C CA  . TYR D 4 80  ? 102.395 124.370 70.000  1.00 69.74  ? 80  TYR R CA  1 
ATOM 5017 C C   . TYR D 4 80  ? 101.316 123.513 69.350  1.00 74.96  ? 80  TYR R C   1 
ATOM 5018 O O   . TYR D 4 80  ? 101.176 123.500 68.122  1.00 80.00  ? 80  TYR R O   1 
ATOM 5019 C CB  . TYR D 4 80  ? 103.651 123.556 70.298  1.00 72.73  ? 80  TYR R CB  1 
ATOM 5020 C CG  . TYR D 4 80  ? 104.132 122.664 69.180  1.00 72.91  ? 80  TYR R CG  1 
ATOM 5021 C CD1 . TYR D 4 80  ? 104.276 123.140 67.893  1.00 69.75  ? 80  TYR R CD1 1 
ATOM 5022 C CD2 . TYR D 4 80  ? 104.499 121.353 69.433  1.00 72.10  ? 80  TYR R CD2 1 
ATOM 5023 C CE1 . TYR D 4 80  ? 104.728 122.325 66.882  1.00 70.17  ? 80  TYR R CE1 1 
ATOM 5024 C CE2 . TYR D 4 80  ? 104.959 120.536 68.431  1.00 71.51  ? 80  TYR R CE2 1 
ATOM 5025 C CZ  . TYR D 4 80  ? 105.072 121.026 67.160  1.00 73.58  ? 80  TYR R CZ  1 
ATOM 5026 O OH  . TYR D 4 80  ? 105.530 120.206 66.157  1.00 76.06  ? 80  TYR R OH  1 
ATOM 5027 N N   . VAL D 4 81  ? 100.544 122.792 70.161  1.00 73.76  ? 81  VAL R N   1 
ATOM 5028 C CA  . VAL D 4 81  ? 99.497  121.924 69.630  1.00 68.20  ? 81  VAL R CA  1 
ATOM 5029 C C   . VAL D 4 81  ? 98.303  122.737 69.152  1.00 65.81  ? 81  VAL R C   1 
ATOM 5030 O O   . VAL D 4 81  ? 97.700  122.419 68.122  1.00 68.40  ? 81  VAL R O   1 
ATOM 5031 C CB  . VAL D 4 81  ? 99.089  120.879 70.682  1.00 69.30  ? 81  VAL R CB  1 
ATOM 5032 C CG1 . VAL D 4 81  ? 97.938  120.036 70.169  1.00 71.94  ? 81  VAL R CG1 1 
ATOM 5033 C CG2 . VAL D 4 81  ? 100.267 119.993 71.025  1.00 69.84  ? 81  VAL R CG2 1 
ATOM 5034 N N   . LEU D 4 82  ? 97.941  123.757 69.913  1.00 61.94  ? 82  LEU R N   1 
ATOM 5035 C CA  . LEU D 4 82  ? 96.831  124.595 69.519  1.00 64.43  ? 82  LEU R CA  1 
ATOM 5036 C C   . LEU D 4 82  ? 97.087  125.130 68.127  1.00 72.48  ? 82  LEU R C   1 
ATOM 5037 O O   . LEU D 4 82  ? 96.219  125.062 67.261  1.00 76.76  ? 82  LEU R O   1 
ATOM 5038 C CB  . LEU D 4 82  ? 96.659  125.738 70.506  1.00 65.53  ? 82  LEU R CB  1 
ATOM 5039 C CG  . LEU D 4 82  ? 96.311  125.328 71.937  1.00 73.72  ? 82  LEU R CG  1 
ATOM 5040 C CD1 . LEU D 4 82  ? 96.282  126.537 72.857  1.00 74.02  ? 82  LEU R CD1 1 
ATOM 5041 C CD2 . LEU D 4 82  ? 94.992  124.573 71.981  1.00 72.80  ? 82  LEU R CD2 1 
ATOM 5042 N N   . GLN D 4 83  ? 98.285  125.657 67.905  1.00 79.92  ? 83  GLN R N   1 
ATOM 5043 C CA  . GLN D 4 83  ? 98.635  126.190 66.595  1.00 75.64  ? 83  GLN R CA  1 
ATOM 5044 C C   . GLN D 4 83  ? 98.886  125.068 65.624  1.00 76.74  ? 83  GLN R C   1 
ATOM 5045 O O   . GLN D 4 83  ? 99.339  123.998 66.019  1.00 78.23  ? 83  GLN R O   1 
ATOM 5046 C CB  . GLN D 4 83  ? 99.883  127.059 66.701  1.00 77.54  ? 83  GLN R CB  1 
ATOM 5047 C CG  . GLN D 4 83  ? 99.767  128.180 67.718  1.00 79.80  ? 83  GLN R CG  1 
ATOM 5048 C CD  . GLN D 4 83  ? 101.108 128.799 68.056  1.00 82.88  ? 83  GLN R CD  1 
ATOM 5049 O OE1 . GLN D 4 83  ? 101.186 129.752 68.829  1.00 82.66  ? 83  GLN R OE1 1 
ATOM 5050 N NE2 . GLN D 4 83  ? 102.174 128.255 67.479  1.00 83.78  ? 83  GLN R NE2 1 
ATOM 5051 N N   . HIS D 4 84  ? 98.602  125.313 64.347  1.00 90.10  ? 84  HIS R N   1 
ATOM 5052 C CA  . HIS D 4 84  ? 98.845  124.302 63.322  1.00 89.38  ? 84  HIS R CA  1 
ATOM 5053 C C   . HIS D 4 84  ? 100.314 124.223 62.990  1.00 93.24  ? 84  HIS R C   1 
ATOM 5054 O O   . HIS D 4 84  ? 100.858 125.114 62.343  1.00 95.13  ? 84  HIS R O   1 
ATOM 5055 C CB  . HIS D 4 84  ? 98.046  124.571 62.048  1.00 88.52  ? 84  HIS R CB  1 
ATOM 5056 C CG  . HIS D 4 84  ? 98.320  123.587 60.955  1.00 90.75  ? 84  HIS R CG  1 
ATOM 5057 N ND1 . HIS D 4 84  ? 97.801  122.311 60.956  1.00 94.62  ? 84  HIS R ND1 1 
ATOM 5058 C CD2 . HIS D 4 84  ? 99.066  123.689 59.830  1.00 91.78  ? 84  HIS R CD2 1 
ATOM 5059 C CE1 . HIS D 4 84  ? 98.212  121.670 59.877  1.00 95.04  ? 84  HIS R CE1 1 
ATOM 5060 N NE2 . HIS D 4 84  ? 98.981  122.484 59.176  1.00 94.19  ? 84  HIS R NE2 1 
ATOM 5061 N N   . ASP D 4 85  ? 100.961 123.168 63.442  1.00 93.28  ? 85  ASP R N   1 
ATOM 5062 C CA  . ASP D 4 85  ? 102.387 122.944 63.177  1.00 93.34  ? 85  ASP R CA  1 
ATOM 5063 C C   . ASP D 4 85  ? 103.352 124.066 63.441  1.00 96.18  ? 85  ASP R C   1 
ATOM 5064 O O   . ASP D 4 85  ? 104.435 124.088 62.875  1.00 101.37 ? 85  ASP R O   1 
ATOM 5065 C CB  . ASP D 4 85  ? 102.551 122.506 61.712  1.00 98.42  ? 85  ASP R CB  1 
ATOM 5066 C CG  . ASP D 4 85  ? 101.443 121.581 61.248  1.00 97.11  ? 85  ASP R CG  1 
ATOM 5067 O OD1 . ASP D 4 85  ? 100.534 121.279 62.049  1.00 98.66  ? 85  ASP R OD1 1 
ATOM 5068 O OD2 . ASP D 4 85  ? 101.480 121.154 60.075  1.00 96.89  ? 85  ASP R OD2 1 
ATOM 5069 N N   . ASN D 4 86  ? 103.025 124.965 64.346  1.00 90.39  ? 86  ASN R N   1 
ATOM 5070 C CA  . ASN D 4 86  ? 103.930 126.099 64.477  1.00 88.29  ? 86  ASN R CA  1 
ATOM 5071 C C   . ASN D 4 86  ? 104.460 126.231 65.899  1.00 88.36  ? 86  ASN R C   1 
ATOM 5072 O O   . ASN D 4 86  ? 103.761 125.943 66.873  1.00 88.13  ? 86  ASN R O   1 
ATOM 5073 C CB  . ASN D 4 86  ? 103.231 127.396 64.066  1.00 87.21  ? 86  ASN R CB  1 
ATOM 5074 N N   . TRP D 4 87  ? 105.704 126.697 66.009  1.00 77.89  ? 87  TRP R N   1 
ATOM 5075 C CA  . TRP D 4 87  ? 106.367 126.881 67.299  1.00 74.05  ? 87  TRP R CA  1 
ATOM 5076 C C   . TRP D 4 87  ? 106.917 128.304 67.323  1.00 73.84  ? 87  TRP R C   1 
ATOM 5077 O O   . TRP D 4 87  ? 108.002 128.568 66.801  1.00 76.13  ? 87  TRP R O   1 
ATOM 5078 C CB  . TRP D 4 87  ? 107.463 125.843 67.501  1.00 72.48  ? 87  TRP R CB  1 
ATOM 5079 C CG  . TRP D 4 87  ? 108.302 126.056 68.710  1.00 70.07  ? 87  TRP R CG  1 
ATOM 5080 C CD1 . TRP D 4 87  ? 109.470 126.736 68.784  1.00 76.67  ? 87  TRP R CD1 1 
ATOM 5081 C CD2 . TRP D 4 87  ? 108.041 125.560 70.025  1.00 65.72  ? 87  TRP R CD2 1 
ATOM 5082 N NE1 . TRP D 4 87  ? 109.956 126.701 70.065  1.00 76.99  ? 87  TRP R NE1 1 
ATOM 5083 C CE2 . TRP D 4 87  ? 109.092 125.982 70.846  1.00 65.58  ? 87  TRP R CE2 1 
ATOM 5084 C CE3 . TRP D 4 87  ? 107.014 124.798 70.586  1.00 74.56  ? 87  TRP R CE3 1 
ATOM 5085 C CZ2 . TRP D 4 87  ? 109.149 125.678 72.198  1.00 69.17  ? 87  TRP R CZ2 1 
ATOM 5086 C CZ3 . TRP D 4 87  ? 107.075 124.494 71.930  1.00 72.55  ? 87  TRP R CZ3 1 
ATOM 5087 C CH2 . TRP D 4 87  ? 108.132 124.934 72.719  1.00 68.81  ? 87  TRP R CH2 1 
ATOM 5088 N N   . SER D 4 88  ? 106.162 129.215 67.936  1.00 75.85  ? 88  SER R N   1 
ATOM 5089 C CA  . SER D 4 88  ? 106.430 130.641 67.790  1.00 76.85  ? 88  SER R CA  1 
ATOM 5090 C C   . SER D 4 88  ? 107.523 131.179 68.703  1.00 75.05  ? 88  SER R C   1 
ATOM 5091 O O   . SER D 4 88  ? 108.321 132.025 68.289  1.00 80.55  ? 88  SER R O   1 
ATOM 5092 C CB  . SER D 4 88  ? 105.164 131.442 68.094  1.00 79.61  ? 88  SER R CB  1 
ATOM 5093 N N   . HIS D 4 89  ? 107.573 130.710 69.946  1.00 74.76  ? 89  HIS R N   1 
ATOM 5094 C CA  . HIS D 4 89  ? 108.456 131.323 70.935  1.00 77.69  ? 89  HIS R CA  1 
ATOM 5095 C C   . HIS D 4 89  ? 109.862 130.926 70.509  1.00 84.23  ? 89  HIS R C   1 
ATOM 5096 O O   . HIS D 4 89  ? 110.298 129.796 70.726  1.00 89.01  ? 89  HIS R O   1 
ATOM 5097 C CB  . HIS D 4 89  ? 108.081 130.865 72.338  1.00 77.56  ? 89  HIS R CB  1 
ATOM 5098 C CG  . HIS D 4 89  ? 106.722 131.308 72.775  1.00 83.50  ? 89  HIS R CG  1 
ATOM 5099 N ND1 . HIS D 4 89  ? 106.448 132.604 73.155  1.00 82.13  ? 89  HIS R ND1 1 
ATOM 5100 C CD2 . HIS D 4 89  ? 105.562 130.624 72.907  1.00 85.16  ? 89  HIS R CD2 1 
ATOM 5101 C CE1 . HIS D 4 89  ? 105.175 132.702 73.493  1.00 83.80  ? 89  HIS R CE1 1 
ATOM 5102 N NE2 . HIS D 4 89  ? 104.615 131.515 73.352  1.00 85.99  ? 89  HIS R NE2 1 
ATOM 5103 N N   . GLY D 4 90  ? 110.580 131.868 69.911  1.00 78.48  ? 90  GLY R N   1 
ATOM 5104 C CA  . GLY D 4 90  ? 112.026 131.876 69.876  1.00 78.57  ? 90  GLY R CA  1 
ATOM 5105 C C   . GLY D 4 90  ? 112.634 130.757 69.058  1.00 80.40  ? 90  GLY R C   1 
ATOM 5106 O O   . GLY D 4 90  ? 111.959 129.914 68.468  1.00 82.63  ? 90  GLY R O   1 
ATOM 5107 N N   . ASP D 4 91  ? 113.966 130.768 69.035  1.00 80.93  ? 91  ASP R N   1 
ATOM 5108 C CA  . ASP D 4 91  ? 114.767 129.686 68.485  1.00 79.38  ? 91  ASP R CA  1 
ATOM 5109 C C   . ASP D 4 91  ? 115.398 128.842 69.578  1.00 78.71  ? 91  ASP R C   1 
ATOM 5110 O O   . ASP D 4 91  ? 116.113 127.882 69.275  1.00 78.83  ? 91  ASP R O   1 
ATOM 5111 C CB  . ASP D 4 91  ? 115.854 130.242 67.561  1.00 77.21  ? 91  ASP R CB  1 
ATOM 5112 N N   . LEU D 4 92  ? 115.153 129.181 70.832  1.00 75.05  ? 92  LEU R N   1 
ATOM 5113 C CA  . LEU D 4 92  ? 115.508 128.379 71.986  1.00 72.78  ? 92  LEU R CA  1 
ATOM 5114 C C   . LEU D 4 92  ? 114.213 127.990 72.687  1.00 73.44  ? 92  LEU R C   1 
ATOM 5115 O O   . LEU D 4 92  ? 113.119 128.173 72.149  1.00 77.23  ? 92  LEU R O   1 
ATOM 5116 C CB  . LEU D 4 92  ? 116.458 129.137 72.914  1.00 81.54  ? 92  LEU R CB  1 
ATOM 5117 N N   . SER D 4 93  ? 114.343 127.422 73.881  1.00 72.25  ? 93  SER R N   1 
ATOM 5118 C CA  . SER D 4 93  ? 113.249 126.872 74.671  1.00 76.45  ? 93  SER R CA  1 
ATOM 5119 C C   . SER D 4 93  ? 112.602 125.683 73.982  1.00 81.22  ? 93  SER R C   1 
ATOM 5120 O O   . SER D 4 93  ? 111.770 125.008 74.595  1.00 84.28  ? 93  SER R O   1 
ATOM 5121 C CB  . SER D 4 93  ? 112.171 127.911 75.004  1.00 78.27  ? 93  SER R CB  1 
ATOM 5122 O OG  . SER D 4 93  ? 111.356 128.176 73.877  1.00 82.65  ? 93  SER R OG  1 
ATOM 5123 N N   . CYS D 4 94  ? 112.955 125.402 72.731  1.00 81.74  ? 94  CYS R N   1 
ATOM 5124 C CA  . CYS D 4 94  ? 112.638 124.127 72.109  1.00 83.49  ? 94  CYS R CA  1 
ATOM 5125 C C   . CYS D 4 94  ? 113.702 123.094 72.419  1.00 82.87  ? 94  CYS R C   1 
ATOM 5126 O O   . CYS D 4 94  ? 113.416 121.891 72.427  1.00 83.97  ? 94  CYS R O   1 
ATOM 5127 C CB  . CYS D 4 94  ? 112.500 124.292 70.593  1.00 78.97  ? 94  CYS R CB  1 
ATOM 5128 N N   . GLN D 4 95  ? 114.921 123.552 72.675  1.00 77.28  ? 95  GLN R N   1 
ATOM 5129 C CA  . GLN D 4 95  ? 115.987 122.730 73.215  1.00 77.19  ? 95  GLN R CA  1 
ATOM 5130 C C   . GLN D 4 95  ? 115.961 122.687 74.732  1.00 74.12  ? 95  GLN R C   1 
ATOM 5131 O O   . GLN D 4 95  ? 116.846 122.079 75.337  1.00 81.04  ? 95  GLN R O   1 
ATOM 5132 C CB  . GLN D 4 95  ? 117.339 123.241 72.713  1.00 78.55  ? 95  GLN R CB  1 
ATOM 5133 N N   . VAL D 4 96  ? 114.974 123.322 75.355  1.00 61.21  ? 96  VAL R N   1 
ATOM 5134 C CA  . VAL D 4 96  ? 114.750 123.230 76.793  1.00 69.10  ? 96  VAL R CA  1 
ATOM 5135 C C   . VAL D 4 96  ? 113.484 122.437 77.095  1.00 72.61  ? 96  VAL R C   1 
ATOM 5136 O O   . VAL D 4 96  ? 113.540 121.380 77.731  1.00 78.44  ? 96  VAL R O   1 
ATOM 5137 C CB  . VAL D 4 96  ? 114.700 124.630 77.440  1.00 72.63  ? 96  VAL R CB  1 
ATOM 5138 C CG1 . VAL D 4 96  ? 114.615 124.510 78.947  1.00 73.26  ? 96  VAL R CG1 1 
ATOM 5139 C CG2 . VAL D 4 96  ? 115.916 125.444 77.034  1.00 74.53  ? 96  VAL R CG2 1 
ATOM 5140 N N   . CYS D 4 97  ? 112.331 122.920 76.625  1.00 68.81  ? 97  CYS R N   1 
ATOM 5141 C CA  . CYS D 4 97  ? 111.094 122.167 76.783  1.00 67.87  ? 97  CYS R CA  1 
ATOM 5142 C C   . CYS D 4 97  ? 111.208 120.787 76.158  1.00 74.62  ? 97  CYS R C   1 
ATOM 5143 O O   . CYS D 4 97  ? 110.581 119.836 76.635  1.00 77.46  ? 97  CYS R O   1 
ATOM 5144 C CB  . CYS D 4 97  ? 109.929 122.936 76.171  1.00 71.13  ? 97  CYS R CB  1 
ATOM 5145 S SG  . CYS D 4 97  ? 109.542 124.492 77.001  1.00 86.25  ? 97  CYS R SG  1 
ATOM 5146 N N   . GLY D 4 98  ? 112.021 120.653 75.110  1.00 74.43  ? 98  GLY R N   1 
ATOM 5147 C CA  . GLY D 4 98  ? 112.307 119.332 74.579  1.00 72.18  ? 98  GLY R CA  1 
ATOM 5148 C C   . GLY D 4 98  ? 112.955 118.424 75.605  1.00 74.04  ? 98  GLY R C   1 
ATOM 5149 O O   . GLY D 4 98  ? 112.579 117.256 75.738  1.00 75.66  ? 98  GLY R O   1 
ATOM 5150 N N   . ILE D 4 99  ? 113.929 118.947 76.352  1.00 65.23  ? 99  ILE R N   1 
ATOM 5151 C CA  . ILE D 4 99  ? 114.542 118.161 77.419  1.00 55.64  ? 99  ILE R CA  1 
ATOM 5152 C C   . ILE D 4 99  ? 113.506 117.796 78.468  1.00 57.13  ? 99  ILE R C   1 
ATOM 5153 O O   . ILE D 4 99  ? 113.323 116.619 78.796  1.00 67.60  ? 99  ILE R O   1 
ATOM 5154 C CB  . ILE D 4 99  ? 115.725 118.918 78.048  1.00 51.26  ? 99  ILE R CB  1 
ATOM 5155 C CG1 . ILE D 4 99  ? 116.832 119.140 77.024  1.00 60.35  ? 99  ILE R CG1 1 
ATOM 5156 C CG2 . ILE D 4 99  ? 116.239 118.182 79.264  1.00 58.10  ? 99  ILE R CG2 1 
ATOM 5157 C CD1 . ILE D 4 99  ? 117.904 120.092 77.500  1.00 64.90  ? 99  ILE R CD1 1 
ATOM 5158 N N   . LEU D 4 100 ? 112.771 118.791 78.965  1.00 56.77  ? 100 LEU R N   1 
ATOM 5159 C CA  . LEU D 4 100 ? 111.824 118.493 80.034  1.00 58.87  ? 100 LEU R CA  1 
ATOM 5160 C C   . LEU D 4 100 ? 110.683 117.593 79.582  1.00 60.34  ? 100 LEU R C   1 
ATOM 5161 O O   . LEU D 4 100 ? 110.014 117.001 80.431  1.00 66.15  ? 100 LEU R O   1 
ATOM 5162 C CB  . LEU D 4 100 ? 111.247 119.759 80.679  1.00 61.93  ? 100 LEU R CB  1 
ATOM 5163 C CG  . LEU D 4 100 ? 112.136 120.816 81.346  1.00 67.50  ? 100 LEU R CG  1 
ATOM 5164 C CD1 . LEU D 4 100 ? 112.556 121.922 80.423  1.00 66.43  ? 100 LEU R CD1 1 
ATOM 5165 C CD2 . LEU D 4 100 ? 111.454 121.394 82.572  1.00 66.81  ? 100 LEU R CD2 1 
ATOM 5166 N N   . LEU D 4 101 ? 110.446 117.458 78.282  1.00 60.20  ? 101 LEU R N   1 
ATOM 5167 C CA  . LEU D 4 101 ? 109.406 116.542 77.840  1.00 61.09  ? 101 LEU R CA  1 
ATOM 5168 C C   . LEU D 4 101 ? 109.935 115.154 77.524  1.00 63.28  ? 101 LEU R C   1 
ATOM 5169 O O   . LEU D 4 101 ? 109.239 114.166 77.783  1.00 69.71  ? 101 LEU R O   1 
ATOM 5170 C CB  . LEU D 4 101 ? 108.690 117.088 76.603  1.00 65.57  ? 101 LEU R CB  1 
ATOM 5171 C CG  . LEU D 4 101 ? 107.533 116.201 76.132  1.00 68.26  ? 101 LEU R CG  1 
ATOM 5172 C CD1 . LEU D 4 101 ? 106.470 116.137 77.205  1.00 68.04  ? 101 LEU R CD1 1 
ATOM 5173 C CD2 . LEU D 4 101 ? 106.939 116.663 74.814  1.00 67.80  ? 101 LEU R CD2 1 
ATOM 5174 N N   . TYR D 4 102 ? 111.151 115.041 76.996  1.00 64.11  ? 102 TYR R N   1 
ATOM 5175 C CA  . TYR D 4 102 ? 111.615 113.751 76.507  1.00 60.99  ? 102 TYR R CA  1 
ATOM 5176 C C   . TYR D 4 102 ? 112.577 113.050 77.458  1.00 62.96  ? 102 TYR R C   1 
ATOM 5177 O O   . TYR D 4 102 ? 112.556 111.820 77.539  1.00 64.42  ? 102 TYR R O   1 
ATOM 5178 C CB  . TYR D 4 102 ? 112.292 113.912 75.147  1.00 62.73  ? 102 TYR R CB  1 
ATOM 5179 C CG  . TYR D 4 102 ? 111.344 113.925 73.970  1.00 63.90  ? 102 TYR R CG  1 
ATOM 5180 C CD1 . TYR D 4 102 ? 110.219 114.729 73.972  1.00 69.86  ? 102 TYR R CD1 1 
ATOM 5181 C CD2 . TYR D 4 102 ? 111.564 113.116 72.866  1.00 58.91  ? 102 TYR R CD2 1 
ATOM 5182 C CE1 . TYR D 4 102 ? 109.356 114.749 72.899  1.00 69.70  ? 102 TYR R CE1 1 
ATOM 5183 C CE2 . TYR D 4 102 ? 110.702 113.128 71.789  1.00 62.00  ? 102 TYR R CE2 1 
ATOM 5184 C CZ  . TYR D 4 102 ? 109.600 113.944 71.814  1.00 66.16  ? 102 TYR R CZ  1 
ATOM 5185 O OH  . TYR D 4 102 ? 108.740 113.957 70.744  1.00 65.42  ? 102 TYR R OH  1 
ATOM 5186 N N   . GLU D 4 103 ? 113.430 113.782 78.180  1.00 62.10  ? 103 GLU R N   1 
ATOM 5187 C CA  . GLU D 4 103 ? 114.451 113.168 79.020  1.00 59.43  ? 103 GLU R CA  1 
ATOM 5188 C C   . GLU D 4 103 ? 114.307 113.515 80.495  1.00 57.53  ? 103 GLU R C   1 
ATOM 5189 O O   . GLU D 4 103 ? 115.188 113.166 81.286  1.00 60.79  ? 103 GLU R O   1 
ATOM 5190 C CB  . GLU D 4 103 ? 115.848 113.562 78.534  1.00 59.13  ? 103 GLU R CB  1 
ATOM 5191 N N   . ASN D 4 104 ? 113.241 114.204 80.886  1.00 56.89  ? 104 ASN R N   1 
ATOM 5192 C CA  . ASN D 4 104 ? 112.955 114.462 82.291  1.00 58.65  ? 104 ASN R CA  1 
ATOM 5193 C C   . ASN D 4 104 ? 112.048 113.411 82.904  1.00 60.08  ? 104 ASN R C   1 
ATOM 5194 O O   . ASN D 4 104 ? 111.729 113.502 84.092  1.00 61.60  ? 104 ASN R O   1 
ATOM 5195 C CB  . ASN D 4 104 ? 112.338 115.851 82.462  1.00 30.00  ? 104 ASN R CB  1 
ATOM 5196 N N   . ILE D 4 105 ? 111.617 112.419 82.122  1.00 60.35  ? 105 ILE R N   1 
ATOM 5197 C CA  . ILE D 4 105 ? 110.796 111.340 82.657  1.00 59.37  ? 105 ILE R CA  1 
ATOM 5198 C C   . ILE D 4 105 ? 111.628 110.256 83.316  1.00 62.57  ? 105 ILE R C   1 
ATOM 5199 O O   . ILE D 4 105 ? 111.064 109.276 83.818  1.00 63.22  ? 105 ILE R O   1 
ATOM 5200 C CB  . ILE D 4 105 ? 109.924 110.735 81.540  1.00 60.20  ? 105 ILE R CB  1 
ATOM 5201 C CG1 . ILE D 4 105 ? 110.798 110.128 80.451  1.00 59.96  ? 105 ILE R CG1 1 
ATOM 5202 C CG2 . ILE D 4 105 ? 109.034 111.795 80.934  1.00 61.32  ? 105 ILE R CG2 1 
ATOM 5203 C CD1 . ILE D 4 105 ? 110.026 109.317 79.442  1.00 60.54  ? 105 ILE R CD1 1 
ATOM 5204 N N   . TYR D 4 106 ? 112.953 110.400 83.331  1.00 59.45  ? 106 TYR R N   1 
ATOM 5205 C CA  . TYR D 4 106 ? 113.831 109.399 83.917  1.00 58.26  ? 106 TYR R CA  1 
ATOM 5206 C C   . TYR D 4 106 ? 114.321 109.759 85.313  1.00 61.60  ? 106 TYR R C   1 
ATOM 5207 O O   . TYR D 4 106 ? 114.687 108.857 86.075  1.00 61.80  ? 106 TYR R O   1 
ATOM 5208 C CB  . TYR D 4 106 ? 115.020 109.140 82.989  1.00 52.92  ? 106 TYR R CB  1 
ATOM 5209 C CG  . TYR D 4 106 ? 114.588 108.502 81.696  1.00 55.70  ? 106 TYR R CG  1 
ATOM 5210 C CD1 . TYR D 4 106 ? 113.538 107.602 81.676  1.00 60.79  ? 106 TYR R CD1 1 
ATOM 5211 C CD2 . TYR D 4 106 ? 115.209 108.803 80.498  1.00 60.63  ? 106 TYR R CD2 1 
ATOM 5212 C CE1 . TYR D 4 106 ? 113.123 107.015 80.506  1.00 61.45  ? 106 TYR R CE1 1 
ATOM 5213 C CE2 . TYR D 4 106 ? 114.797 108.217 79.319  1.00 57.24  ? 106 TYR R CE2 1 
ATOM 5214 C CZ  . TYR D 4 106 ? 113.755 107.325 79.332  1.00 58.94  ? 106 TYR R CZ  1 
ATOM 5215 O OH  . TYR D 4 106 ? 113.328 106.732 78.173  1.00 61.79  ? 106 TYR R OH  1 
ATOM 5216 N N   . ILE D 4 107 ? 114.313 111.038 85.683  1.00 54.30  ? 107 ILE R N   1 
ATOM 5217 C CA  . ILE D 4 107 ? 114.528 111.385 87.082  1.00 49.10  ? 107 ILE R CA  1 
ATOM 5218 C C   . ILE D 4 107 ? 113.436 110.762 87.940  1.00 60.21  ? 107 ILE R C   1 
ATOM 5219 O O   . ILE D 4 107 ? 113.691 110.265 89.050  1.00 70.10  ? 107 ILE R O   1 
ATOM 5220 C CB  . ILE D 4 107 ? 114.586 112.911 87.246  1.00 50.31  ? 107 ILE R CB  1 
ATOM 5221 C CG1 . ILE D 4 107 ? 115.680 113.490 86.357  1.00 51.57  ? 107 ILE R CG1 1 
ATOM 5222 C CG2 . ILE D 4 107 ? 114.833 113.285 88.689  1.00 53.82  ? 107 ILE R CG2 1 
ATOM 5223 C CD1 . ILE D 4 107 ? 117.024 112.855 86.560  1.00 57.11  ? 107 ILE R CD1 1 
ATOM 5224 N N   . SER D 4 108 ? 112.207 110.752 87.424  1.00 56.04  ? 108 SER R N   1 
ATOM 5225 C CA  . SER D 4 108 ? 111.099 110.139 88.141  1.00 56.04  ? 108 SER R CA  1 
ATOM 5226 C C   . SER D 4 108 ? 111.334 108.650 88.359  1.00 60.59  ? 108 SER R C   1 
ATOM 5227 O O   . SER D 4 108 ? 111.127 108.136 89.464  1.00 65.56  ? 108 SER R O   1 
ATOM 5228 C CB  . SER D 4 108 ? 109.795 110.374 87.383  1.00 59.33  ? 108 SER R CB  1 
ATOM 5229 O OG  . SER D 4 108 ? 109.506 111.756 87.288  1.00 61.88  ? 108 SER R OG  1 
ATOM 5230 N N   . VAL D 4 109 ? 111.773 107.936 87.318  1.00 49.24  ? 109 VAL R N   1 
ATOM 5231 C CA  . VAL D 4 109 ? 111.976 106.502 87.488  1.00 43.57  ? 109 VAL R CA  1 
ATOM 5232 C C   . VAL D 4 109 ? 113.157 106.239 88.410  1.00 47.95  ? 109 VAL R C   1 
ATOM 5233 O O   . VAL D 4 109 ? 113.134 105.285 89.199  1.00 60.04  ? 109 VAL R O   1 
ATOM 5234 C CB  . VAL D 4 109 ? 112.131 105.782 86.134  1.00 49.73  ? 109 VAL R CB  1 
ATOM 5235 C CG1 . VAL D 4 109 ? 110.877 105.951 85.297  1.00 53.46  ? 109 VAL R CG1 1 
ATOM 5236 C CG2 . VAL D 4 109 ? 113.355 106.233 85.389  1.00 54.75  ? 109 VAL R CG2 1 
ATOM 5237 N N   . GLY D 4 110 ? 114.194 107.078 88.351  1.00 42.96  ? 110 GLY R N   1 
ATOM 5238 C CA  . GLY D 4 110 ? 115.292 106.933 89.292  1.00 49.22  ? 110 GLY R CA  1 
ATOM 5239 C C   . GLY D 4 110 ? 114.836 107.054 90.732  1.00 50.62  ? 110 GLY R C   1 
ATOM 5240 O O   . GLY D 4 110 ? 115.227 106.255 91.592  1.00 54.14  ? 110 GLY R O   1 
ATOM 5241 N N   . PHE D 4 111 ? 113.977 108.030 91.013  1.00 40.76  ? 111 PHE R N   1 
ATOM 5242 C CA  . PHE D 4 111 ? 113.515 108.187 92.385  1.00 46.34  ? 111 PHE R CA  1 
ATOM 5243 C C   . PHE D 4 111 ? 112.533 107.091 92.785  1.00 49.45  ? 111 PHE R C   1 
ATOM 5244 O O   . PHE D 4 111 ? 112.491 106.699 93.960  1.00 60.53  ? 111 PHE R O   1 
ATOM 5245 C CB  . PHE D 4 111 ? 112.928 109.577 92.570  1.00 48.91  ? 111 PHE R CB  1 
ATOM 5246 C CG  . PHE D 4 111 ? 113.972 110.627 92.757  1.00 51.49  ? 111 PHE R CG  1 
ATOM 5247 C CD1 . PHE D 4 111 ? 114.926 110.490 93.740  1.00 54.55  ? 111 PHE R CD1 1 
ATOM 5248 C CD2 . PHE D 4 111 ? 114.034 111.724 91.929  1.00 47.71  ? 111 PHE R CD2 1 
ATOM 5249 C CE1 . PHE D 4 111 ? 115.899 111.440 93.910  1.00 51.54  ? 111 PHE R CE1 1 
ATOM 5250 C CE2 . PHE D 4 111 ? 115.010 112.672 92.099  1.00 48.37  ? 111 PHE R CE2 1 
ATOM 5251 C CZ  . PHE D 4 111 ? 115.941 112.527 93.086  1.00 46.00  ? 111 PHE R CZ  1 
ATOM 5252 N N   . LEU D 4 112 ? 111.772 106.552 91.832  1.00 47.19  ? 112 LEU R N   1 
ATOM 5253 C CA  . LEU D 4 112 ? 110.957 105.379 92.134  1.00 47.21  ? 112 LEU R CA  1 
ATOM 5254 C C   . LEU D 4 112 ? 111.827 104.199 92.554  1.00 52.60  ? 112 LEU R C   1 
ATOM 5255 O O   . LEU D 4 112 ? 111.515 103.500 93.529  1.00 56.29  ? 112 LEU R O   1 
ATOM 5256 C CB  . LEU D 4 112 ? 110.098 104.998 90.931  1.00 47.06  ? 112 LEU R CB  1 
ATOM 5257 C CG  . LEU D 4 112 ? 109.071 105.997 90.413  1.00 49.74  ? 112 LEU R CG  1 
ATOM 5258 C CD1 . LEU D 4 112 ? 108.456 105.490 89.134  1.00 49.01  ? 112 LEU R CD1 1 
ATOM 5259 C CD2 . LEU D 4 112 ? 108.006 106.266 91.452  1.00 54.35  ? 112 LEU R CD2 1 
ATOM 5260 N N   . CYS D 4 113 ? 112.923 103.958 91.829  1.00 41.63  ? 113 CYS R N   1 
ATOM 5261 C CA  . CYS D 4 113 ? 113.822 102.872 92.210  1.00 36.04  ? 113 CYS R CA  1 
ATOM 5262 C C   . CYS D 4 113 ? 114.457 103.126 93.572  1.00 50.91  ? 113 CYS R C   1 
ATOM 5263 O O   . CYS D 4 113 ? 114.648 102.189 94.361  1.00 61.66  ? 113 CYS R O   1 
ATOM 5264 C CB  . CYS D 4 113 ? 114.892 102.662 91.145  1.00 42.12  ? 113 CYS R CB  1 
ATOM 5265 S SG  . CYS D 4 113 ? 114.271 102.565 89.468  1.00 70.52  ? 113 CYS R SG  1 
ATOM 5266 N N   . CYS D 4 114 ? 114.799 104.382 93.866  1.00 51.35  ? 114 CYS R N   1 
ATOM 5267 C CA  . CYS D 4 114 ? 115.336 104.695 95.188  1.00 48.21  ? 114 CYS R CA  1 
ATOM 5268 C C   . CYS D 4 114 ? 114.333 104.355 96.282  1.00 45.42  ? 114 CYS R C   1 
ATOM 5269 O O   . CYS D 4 114 ? 114.696 103.767 97.309  1.00 54.42  ? 114 CYS R O   1 
ATOM 5270 C CB  . CYS D 4 114 ? 115.732 106.167 95.271  1.00 51.76  ? 114 CYS R CB  1 
ATOM 5271 S SG  . CYS D 4 114 ? 117.100 106.645 94.195  1.00 74.40  ? 114 CYS R SG  1 
ATOM 5272 N N   . ILE D 4 115 ? 113.064 104.712 96.077  1.00 44.90  ? 115 ILE R N   1 
ATOM 5273 C CA  . ILE D 4 115 ? 112.038 104.400 97.068  1.00 47.79  ? 115 ILE R CA  1 
ATOM 5274 C C   . ILE D 4 115 ? 111.895 102.894 97.232  1.00 46.36  ? 115 ILE R C   1 
ATOM 5275 O O   . ILE D 4 115 ? 111.748 102.386 98.352  1.00 56.01  ? 115 ILE R O   1 
ATOM 5276 C CB  . ILE D 4 115 ? 110.701 105.055 96.682  1.00 44.69  ? 115 ILE R CB  1 
ATOM 5277 C CG1 . ILE D 4 115 ? 110.826 106.573 96.707  1.00 46.13  ? 115 ILE R CG1 1 
ATOM 5278 C CG2 . ILE D 4 115 ? 109.608 104.618 97.628  1.00 45.73  ? 115 ILE R CG2 1 
ATOM 5279 C CD1 . ILE D 4 115 ? 109.735 107.278 95.960  1.00 48.51  ? 115 ILE R CD1 1 
ATOM 5280 N N   . SER D 4 116 ? 111.937 102.154 96.123  1.00 38.33  ? 116 SER R N   1 
ATOM 5281 C CA  . SER D 4 116 ? 111.801 100.701 96.200  1.00 40.42  ? 116 SER R CA  1 
ATOM 5282 C C   . SER D 4 116 ? 112.934 100.077 97.008  1.00 45.30  ? 116 SER R C   1 
ATOM 5283 O O   . SER D 4 116 ? 112.699 99.214  97.865  1.00 49.59  ? 116 SER R O   1 
ATOM 5284 C CB  . SER D 4 116 ? 111.755 100.106 94.798  1.00 47.73  ? 116 SER R CB  1 
ATOM 5285 N N   . VAL D 4 117 ? 114.172 100.505 96.757  1.00 42.10  ? 117 VAL R N   1 
ATOM 5286 C CA  . VAL D 4 117 ? 115.303 99.942  97.492  1.00 41.84  ? 117 VAL R CA  1 
ATOM 5287 C C   . VAL D 4 117 ? 115.238 100.326 98.965  1.00 47.68  ? 117 VAL R C   1 
ATOM 5288 O O   . VAL D 4 117 ? 115.533 99.507  99.846  1.00 50.83  ? 117 VAL R O   1 
ATOM 5289 C CB  . VAL D 4 117 ? 116.632 100.365 96.845  1.00 42.22  ? 117 VAL R CB  1 
ATOM 5290 C CG1 . VAL D 4 117 ? 117.776 100.215 97.821  1.00 48.70  ? 117 VAL R CG1 1 
ATOM 5291 C CG2 . VAL D 4 117 ? 116.902 99.517  95.634  1.00 45.39  ? 117 VAL R CG2 1 
ATOM 5292 N N   . ASP D 4 118 ? 114.843 101.566 99.264  1.00 42.32  ? 118 ASP R N   1 
ATOM 5293 C CA  . ASP D 4 118 ? 114.697 101.965 100.660 1.00 38.83  ? 118 ASP R CA  1 
ATOM 5294 C C   . ASP D 4 118 ? 113.664 101.104 101.373 1.00 47.27  ? 118 ASP R C   1 
ATOM 5295 O O   . ASP D 4 118 ? 113.897 100.641 102.497 1.00 53.68  ? 118 ASP R O   1 
ATOM 5296 C CB  . ASP D 4 118 ? 114.308 103.436 100.750 1.00 44.43  ? 118 ASP R CB  1 
ATOM 5297 C CG  . ASP D 4 118 ? 114.888 104.111 101.965 1.00 56.04  ? 118 ASP R CG  1 
ATOM 5298 O OD1 . ASP D 4 118 ? 115.974 103.694 102.408 1.00 61.39  ? 118 ASP R OD1 1 
ATOM 5299 O OD2 . ASP D 4 118 ? 114.258 105.057 102.480 1.00 55.31  ? 118 ASP R OD2 1 
ATOM 5300 N N   . ARG D 4 119 ? 112.523 100.859 100.726 1.00 40.38  ? 119 ARG R N   1 
ATOM 5301 C CA  . ARG D 4 119 ? 111.504 100.008 101.328 1.00 27.37  ? 119 ARG R CA  1 
ATOM 5302 C C   . ARG D 4 119 ? 112.028 98.598  101.549 1.00 35.87  ? 119 ARG R C   1 
ATOM 5303 O O   . ARG D 4 119 ? 111.800 98.004  102.609 1.00 46.60  ? 119 ARG R O   1 
ATOM 5304 C CB  . ARG D 4 119 ? 110.261 99.981  100.445 1.00 32.78  ? 119 ARG R CB  1 
ATOM 5305 C CG  . ARG D 4 119 ? 109.440 101.247 100.489 1.00 34.96  ? 119 ARG R CG  1 
ATOM 5306 C CD  . ARG D 4 119 ? 108.508 101.320 99.302  1.00 38.08  ? 119 ARG R CD  1 
ATOM 5307 N NE  . ARG D 4 119 ? 107.364 102.187 99.549  1.00 37.92  ? 119 ARG R NE  1 
ATOM 5308 C CZ  . ARG D 4 119 ? 106.344 102.330 98.714  1.00 42.51  ? 119 ARG R CZ  1 
ATOM 5309 N NH1 . ARG D 4 119 ? 106.322 101.663 97.572  1.00 47.09  ? 119 ARG R NH1 1 
ATOM 5310 N NH2 . ARG D 4 119 ? 105.346 103.141 99.017  1.00 41.80  ? 119 ARG R NH2 1 
ATOM 5311 N N   . TYR D 4 120 ? 112.741 98.049  100.565 1.00 34.19  ? 120 TYR R N   1 
ATOM 5312 C CA  . TYR D 4 120 ? 113.242 96.685  100.692 1.00 25.62  ? 120 TYR R CA  1 
ATOM 5313 C C   . TYR D 4 120 ? 114.228 96.557  101.842 1.00 34.92  ? 120 TYR R C   1 
ATOM 5314 O O   . TYR D 4 120 ? 114.167 95.592  102.612 1.00 48.93  ? 120 TYR R O   1 
ATOM 5315 C CB  . TYR D 4 120 ? 113.887 96.240  99.388  1.00 32.76  ? 120 TYR R CB  1 
ATOM 5316 C CG  . TYR D 4 120 ? 114.569 94.902  99.466  1.00 36.61  ? 120 TYR R CG  1 
ATOM 5317 C CD1 . TYR D 4 120 ? 113.865 93.766  99.801  1.00 42.26  ? 120 TYR R CD1 1 
ATOM 5318 C CD2 . TYR D 4 120 ? 115.911 94.773  99.178  1.00 37.83  ? 120 TYR R CD2 1 
ATOM 5319 C CE1 . TYR D 4 120 ? 114.484 92.543  99.863  1.00 38.24  ? 120 TYR R CE1 1 
ATOM 5320 C CE2 . TYR D 4 120 ? 116.535 93.557  99.238  1.00 35.63  ? 120 TYR R CE2 1 
ATOM 5321 C CZ  . TYR D 4 120 ? 115.818 92.447  99.582  1.00 38.53  ? 120 TYR R CZ  1 
ATOM 5322 O OH  . TYR D 4 120 ? 116.436 91.225  99.644  1.00 48.35  ? 120 TYR R OH  1 
ATOM 5323 N N   . LEU D 4 121 ? 115.145 97.514  101.979 1.00 38.67  ? 121 LEU R N   1 
ATOM 5324 C CA  . LEU D 4 121 ? 116.075 97.468  103.104 1.00 35.05  ? 121 LEU R CA  1 
ATOM 5325 C C   . LEU D 4 121 ? 115.419 97.824  104.427 1.00 38.23  ? 121 LEU R C   1 
ATOM 5326 O O   . LEU D 4 121 ? 115.990 97.528  105.481 1.00 52.20  ? 121 LEU R O   1 
ATOM 5327 C CB  . LEU D 4 121 ? 117.277 98.379  102.858 1.00 39.66  ? 121 LEU R CB  1 
ATOM 5328 C CG  . LEU D 4 121 ? 118.391 97.867  101.943 1.00 40.51  ? 121 LEU R CG  1 
ATOM 5329 C CD1 . LEU D 4 121 ? 118.002 97.803  100.488 1.00 45.49  ? 121 LEU R CD1 1 
ATOM 5330 C CD2 . LEU D 4 121 ? 119.601 98.751  102.115 1.00 42.99  ? 121 LEU R CD2 1 
ATOM 5331 N N   . ALA D 4 122 ? 114.247 98.446  104.407 1.00 36.51  ? 122 ALA R N   1 
ATOM 5332 C CA  . ALA D 4 122 ? 113.547 98.731  105.649 1.00 36.94  ? 122 ALA R CA  1 
ATOM 5333 C C   . ALA D 4 122 ? 112.675 97.582  106.136 1.00 37.34  ? 122 ALA R C   1 
ATOM 5334 O O   . ALA D 4 122 ? 112.479 97.446  107.347 1.00 46.09  ? 122 ALA R O   1 
ATOM 5335 C CB  . ALA D 4 122 ? 112.683 99.985  105.489 1.00 41.96  ? 122 ALA R CB  1 
ATOM 5336 N N   . VAL D 4 123 ? 112.139 96.752  105.241 1.00 29.23  ? 123 VAL R N   1 
ATOM 5337 C CA  . VAL D 4 123 ? 111.186 95.722  105.644 1.00 17.97  ? 123 VAL R CA  1 
ATOM 5338 C C   . VAL D 4 123 ? 111.740 94.311  105.548 1.00 28.39  ? 123 VAL R C   1 
ATOM 5339 O O   . VAL D 4 123 ? 111.135 93.392  106.121 1.00 41.44  ? 123 VAL R O   1 
ATOM 5340 C CB  . VAL D 4 123 ? 109.874 95.808  104.838 1.00 25.67  ? 123 VAL R CB  1 
ATOM 5341 C CG1 . VAL D 4 123 ? 109.197 97.142  105.063 1.00 39.78  ? 123 VAL R CG1 1 
ATOM 5342 C CG2 . VAL D 4 123 ? 110.123 95.539  103.375 1.00 32.74  ? 123 VAL R CG2 1 
ATOM 5343 N N   . ALA D 4 124 ? 112.855 94.098  104.857 1.00 27.80  ? 124 ALA R N   1 
ATOM 5344 C CA  . ALA D 4 124 ? 113.425 92.764  104.735 1.00 21.96  ? 124 ALA R CA  1 
ATOM 5345 C C   . ALA D 4 124 ? 114.696 92.566  105.539 1.00 40.71  ? 124 ALA R C   1 
ATOM 5346 O O   . ALA D 4 124 ? 114.999 91.433  105.916 1.00 49.10  ? 124 ALA R O   1 
ATOM 5347 C CB  . ALA D 4 124 ? 113.714 92.437  103.269 1.00 30.32  ? 124 ALA R CB  1 
ATOM 5348 N N   . HIS D 4 125 ? 115.447 93.630  105.807 1.00 47.70  ? 125 HIS R N   1 
ATOM 5349 C CA  . HIS D 4 125 ? 116.627 93.583  106.669 1.00 44.59  ? 125 HIS R CA  1 
ATOM 5350 C C   . HIS D 4 125 ? 116.549 94.726  107.670 1.00 49.20  ? 125 HIS R C   1 
ATOM 5351 O O   . HIS D 4 125 ? 117.269 95.724  107.552 1.00 56.32  ? 125 HIS R O   1 
ATOM 5352 C CB  . HIS D 4 125 ? 117.912 93.671  105.849 1.00 44.76  ? 125 HIS R CB  1 
ATOM 5353 C CG  . HIS D 4 125 ? 117.996 92.673  104.742 1.00 43.23  ? 125 HIS R CG  1 
ATOM 5354 N ND1 . HIS D 4 125 ? 118.416 91.377  104.940 1.00 48.00  ? 125 HIS R ND1 1 
ATOM 5355 C CD2 . HIS D 4 125 ? 117.734 92.785  103.420 1.00 45.21  ? 125 HIS R CD2 1 
ATOM 5356 C CE1 . HIS D 4 125 ? 118.400 90.731  103.789 1.00 52.60  ? 125 HIS R CE1 1 
ATOM 5357 N NE2 . HIS D 4 125 ? 117.991 91.563  102.850 1.00 52.88  ? 125 HIS R NE2 1 
ATOM 5358 N N   . PRO D 4 126 ? 115.681 94.614  108.677 1.00 31.40  ? 126 PRO R N   1 
ATOM 5359 C CA  . PRO D 4 126 ? 115.468 95.748  109.583 1.00 38.82  ? 126 PRO R CA  1 
ATOM 5360 C C   . PRO D 4 126 ? 116.570 95.951  110.604 1.00 44.29  ? 126 PRO R C   1 
ATOM 5361 O O   . PRO D 4 126 ? 116.669 97.050  111.163 1.00 49.06  ? 126 PRO R O   1 
ATOM 5362 C CB  . PRO D 4 126 ? 114.147 95.397  110.269 1.00 39.33  ? 126 PRO R CB  1 
ATOM 5363 C CG  . PRO D 4 126 ? 114.116 93.922  110.260 1.00 40.25  ? 126 PRO R CG  1 
ATOM 5364 C CD  . PRO D 4 126 ? 114.836 93.463  109.025 1.00 31.88  ? 126 PRO R CD  1 
ATOM 5365 N N   . PHE D 4 127 ? 117.394 94.942  110.869 1.00 47.19  ? 127 PHE R N   1 
ATOM 5366 C CA  . PHE D 4 127 ? 118.441 95.041  111.876 1.00 42.68  ? 127 PHE R CA  1 
ATOM 5367 C C   . PHE D 4 127 ? 119.786 95.458  111.308 1.00 44.30  ? 127 PHE R C   1 
ATOM 5368 O O   . PHE D 4 127 ? 120.733 95.641  112.077 1.00 54.17  ? 127 PHE R O   1 
ATOM 5369 C CB  . PHE D 4 127 ? 118.610 93.707  112.599 1.00 43.06  ? 127 PHE R CB  1 
ATOM 5370 C CG  . PHE D 4 127 ? 117.622 93.482  113.689 1.00 39.48  ? 127 PHE R CG  1 
ATOM 5371 C CD1 . PHE D 4 127 ? 116.861 94.520  114.171 1.00 42.56  ? 127 PHE R CD1 1 
ATOM 5372 C CD2 . PHE D 4 127 ? 117.454 92.230  114.232 1.00 40.41  ? 127 PHE R CD2 1 
ATOM 5373 C CE1 . PHE D 4 127 ? 115.954 94.311  115.173 1.00 44.85  ? 127 PHE R CE1 1 
ATOM 5374 C CE2 . PHE D 4 127 ? 116.546 92.018  115.233 1.00 43.03  ? 127 PHE R CE2 1 
ATOM 5375 C CZ  . PHE D 4 127 ? 115.796 93.061  115.704 1.00 45.84  ? 127 PHE R CZ  1 
ATOM 5376 N N   . ARG D 4 128 ? 119.904 95.607  109.996 1.00 47.66  ? 128 ARG R N   1 
ATOM 5377 C CA  . ARG D 4 128 ? 121.186 95.885  109.374 1.00 52.35  ? 128 ARG R CA  1 
ATOM 5378 C C   . ARG D 4 128 ? 121.049 97.058  108.414 1.00 59.36  ? 128 ARG R C   1 
ATOM 5379 O O   . ARG D 4 128 ? 119.944 97.504  108.093 1.00 63.88  ? 128 ARG R O   1 
ATOM 5380 C CB  . ARG D 4 128 ? 121.722 94.645  108.655 1.00 55.94  ? 128 ARG R CB  1 
ATOM 5381 C CG  . ARG D 4 128 ? 122.124 93.553  109.614 1.00 55.83  ? 128 ARG R CG  1 
ATOM 5382 C CD  . ARG D 4 128 ? 123.097 92.563  108.995 1.00 59.61  ? 128 ARG R CD  1 
ATOM 5383 N NE  . ARG D 4 128 ? 123.796 91.730  109.978 1.00 64.09  ? 128 ARG R NE  1 
ATOM 5384 C CZ  . ARG D 4 128 ? 123.226 91.026  110.958 1.00 65.61  ? 128 ARG R CZ  1 
ATOM 5385 N NH1 . ARG D 4 128 ? 123.989 90.323  111.782 1.00 63.95  ? 128 ARG R NH1 1 
ATOM 5386 N NH2 . ARG D 4 128 ? 121.908 90.976  111.100 1.00 62.80  ? 128 ARG R NH2 1 
ATOM 5387 N N   . PHE D 4 129 ? 122.200 97.562  107.966 1.00 58.90  ? 129 PHE R N   1 
ATOM 5388 C CA  . PHE D 4 129 ? 122.274 98.706  107.058 1.00 51.70  ? 129 PHE R CA  1 
ATOM 5389 C C   . PHE D 4 129 ? 121.595 99.940  107.651 1.00 57.31  ? 129 PHE R C   1 
ATOM 5390 O O   . PHE D 4 129 ? 120.695 100.530 107.053 1.00 62.03  ? 129 PHE R O   1 
ATOM 5391 C CB  . PHE D 4 129 ? 121.680 98.361  105.694 1.00 57.10  ? 129 PHE R CB  1 
ATOM 5392 C CG  . PHE D 4 129 ? 122.177 97.072  105.127 1.00 57.38  ? 129 PHE R CG  1 
ATOM 5393 C CD1 . PHE D 4 129 ? 123.458 96.972  104.628 1.00 59.87  ? 129 PHE R CD1 1 
ATOM 5394 C CD2 . PHE D 4 129 ? 121.361 95.963  105.080 1.00 57.52  ? 129 PHE R CD2 1 
ATOM 5395 C CE1 . PHE D 4 129 ? 123.918 95.790  104.102 1.00 62.16  ? 129 PHE R CE1 1 
ATOM 5396 C CE2 . PHE D 4 129 ? 121.817 94.778  104.551 1.00 61.91  ? 129 PHE R CE2 1 
ATOM 5397 C CZ  . PHE D 4 129 ? 123.096 94.693  104.063 1.00 63.61  ? 129 PHE R CZ  1 
ATOM 5398 N N   . HIS D 4 130 ? 122.035 100.329 108.848 1.00 58.87  ? 130 HIS R N   1 
ATOM 5399 C CA  . HIS D 4 130 ? 121.516 101.540 109.474 1.00 56.61  ? 130 HIS R CA  1 
ATOM 5400 C C   . HIS D 4 130 ? 122.108 102.803 108.873 1.00 59.47  ? 130 HIS R C   1 
ATOM 5401 O O   . HIS D 4 130 ? 121.456 103.851 108.882 1.00 64.31  ? 130 HIS R O   1 
ATOM 5402 C CB  . HIS D 4 130 ? 121.781 101.513 110.978 1.00 61.04  ? 130 HIS R CB  1 
ATOM 5403 C CG  . HIS D 4 130 ? 120.758 100.756 111.762 1.00 64.07  ? 130 HIS R CG  1 
ATOM 5404 N ND1 . HIS D 4 130 ? 121.091 99.900  112.787 1.00 64.46  ? 130 HIS R ND1 1 
ATOM 5405 C CD2 . HIS D 4 130 ? 119.406 100.755 111.695 1.00 62.81  ? 130 HIS R CD2 1 
ATOM 5406 C CE1 . HIS D 4 130 ? 119.989 99.386  113.304 1.00 63.14  ? 130 HIS R CE1 1 
ATOM 5407 N NE2 . HIS D 4 130 ? 118.953 99.891  112.660 1.00 64.28  ? 130 HIS R NE2 1 
ATOM 5408 N N   . GLN D 4 131 ? 123.331 102.732 108.356 1.00 60.39  ? 131 GLN R N   1 
ATOM 5409 C CA  . GLN D 4 131 ? 124.006 103.903 107.816 1.00 61.87  ? 131 GLN R CA  1 
ATOM 5410 C C   . GLN D 4 131 ? 123.584 104.243 106.392 1.00 64.03  ? 131 GLN R C   1 
ATOM 5411 O O   . GLN D 4 131 ? 123.904 105.335 105.915 1.00 68.29  ? 131 GLN R O   1 
ATOM 5412 C CB  . GLN D 4 131 ? 125.518 103.690 107.877 1.00 61.07  ? 131 GLN R CB  1 
ATOM 5413 C CG  . GLN D 4 131 ? 126.015 102.583 106.984 1.00 61.08  ? 131 GLN R CG  1 
ATOM 5414 C CD  . GLN D 4 131 ? 127.471 102.259 107.229 1.00 67.41  ? 131 GLN R CD  1 
ATOM 5415 O OE1 . GLN D 4 131 ? 128.163 102.973 107.953 1.00 67.22  ? 131 GLN R OE1 1 
ATOM 5416 N NE2 . GLN D 4 131 ? 127.945 101.175 106.628 1.00 68.77  ? 131 GLN R NE2 1 
ATOM 5417 N N   . PHE D 4 132 ? 122.881 103.348 105.706 1.00 55.74  ? 132 PHE R N   1 
ATOM 5418 C CA  . PHE D 4 132 ? 122.403 103.607 104.356 1.00 42.18  ? 132 PHE R CA  1 
ATOM 5419 C C   . PHE D 4 132 ? 121.014 104.221 104.339 1.00 49.17  ? 132 PHE R C   1 
ATOM 5420 O O   . PHE D 4 132 ? 120.516 104.562 103.263 1.00 62.88  ? 132 PHE R O   1 
ATOM 5421 C CB  . PHE D 4 132 ? 122.387 102.317 103.540 1.00 48.88  ? 132 PHE R CB  1 
ATOM 5422 C CG  . PHE D 4 132 ? 123.744 101.832 103.131 1.00 54.26  ? 132 PHE R CG  1 
ATOM 5423 C CD1 . PHE D 4 132 ? 124.888 102.394 103.652 1.00 57.62  ? 132 PHE R CD1 1 
ATOM 5424 C CD2 . PHE D 4 132 ? 123.870 100.797 102.229 1.00 59.01  ? 132 PHE R CD2 1 
ATOM 5425 C CE1 . PHE D 4 132 ? 126.129 101.936 103.280 1.00 60.20  ? 132 PHE R CE1 1 
ATOM 5426 C CE2 . PHE D 4 132 ? 125.109 100.337 101.853 1.00 60.35  ? 132 PHE R CE2 1 
ATOM 5427 C CZ  . PHE D 4 132 ? 126.239 100.907 102.378 1.00 61.16  ? 132 PHE R CZ  1 
ATOM 5428 N N   . ARG D 4 133 ? 120.377 104.363 105.496 1.00 49.19  ? 133 ARG R N   1 
ATOM 5429 C CA  . ARG D 4 133 ? 119.037 104.923 105.573 1.00 55.14  ? 133 ARG R CA  1 
ATOM 5430 C C   . ARG D 4 133 ? 119.023 106.185 106.421 1.00 60.94  ? 133 ARG R C   1 
ATOM 5431 O O   . ARG D 4 133 ? 118.150 106.355 107.277 1.00 66.05  ? 133 ARG R O   1 
ATOM 5432 C CB  . ARG D 4 133 ? 118.058 103.900 106.142 1.00 53.68  ? 133 ARG R CB  1 
ATOM 5433 C CG  . ARG D 4 133 ? 117.445 102.998 105.102 1.00 56.22  ? 133 ARG R CG  1 
ATOM 5434 C CD  . ARG D 4 133 ? 116.925 101.719 105.714 1.00 59.38  ? 133 ARG R CD  1 
ATOM 5435 N NE  . ARG D 4 133 ? 116.403 101.930 107.055 1.00 58.37  ? 133 ARG R NE  1 
ATOM 5436 C CZ  . ARG D 4 133 ? 116.589 101.088 108.062 1.00 57.81  ? 133 ARG R CZ  1 
ATOM 5437 N NH1 . ARG D 4 133 ? 117.290 99.980  107.880 1.00 56.00  ? 133 ARG R NH1 1 
ATOM 5438 N NH2 . ARG D 4 133 ? 116.080 101.358 109.253 1.00 57.19  ? 133 ARG R NH2 1 
ATOM 5439 N N   . THR D 4 134 ? 119.988 107.069 106.196 1.00 66.64  ? 134 THR R N   1 
ATOM 5440 C CA  . THR D 4 134 ? 120.060 108.354 106.871 1.00 64.09  ? 134 THR R CA  1 
ATOM 5441 C C   . THR D 4 134 ? 119.826 109.478 105.869 1.00 69.03  ? 134 THR R C   1 
ATOM 5442 O O   . THR D 4 134 ? 119.765 109.265 104.656 1.00 68.82  ? 134 THR R O   1 
ATOM 5443 C CB  . THR D 4 134 ? 121.413 108.530 107.567 1.00 61.25  ? 134 THR R CB  1 
ATOM 5444 O OG1 . THR D 4 134 ? 122.465 108.448 106.598 1.00 70.90  ? 134 THR R OG1 1 
ATOM 5445 C CG2 . THR D 4 134 ? 121.612 107.446 108.608 1.00 61.93  ? 134 THR R CG2 1 
ATOM 5446 N N   . LEU D 4 135 ? 119.688 110.693 106.401 1.00 56.32  ? 135 LEU R N   1 
ATOM 5447 C CA  . LEU D 4 135 ? 119.373 111.839 105.557 1.00 45.99  ? 135 LEU R CA  1 
ATOM 5448 C C   . LEU D 4 135 ? 120.541 112.201 104.648 1.00 54.90  ? 135 LEU R C   1 
ATOM 5449 O O   . LEU D 4 135 ? 120.335 112.603 103.495 1.00 65.22  ? 135 LEU R O   1 
ATOM 5450 C CB  . LEU D 4 135 ? 118.980 113.029 106.426 1.00 43.25  ? 135 LEU R CB  1 
ATOM 5451 C CG  . LEU D 4 135 ? 117.482 113.217 106.648 1.00 50.99  ? 135 LEU R CG  1 
ATOM 5452 C CD1 . LEU D 4 135 ? 116.922 112.098 107.491 1.00 56.67  ? 135 LEU R CD1 1 
ATOM 5453 C CD2 . LEU D 4 135 ? 117.210 114.558 107.300 1.00 53.91  ? 135 LEU R CD2 1 
ATOM 5454 N N   . LYS D 4 136 ? 121.771 112.072 105.146 1.00 44.05  ? 136 LYS R N   1 
ATOM 5455 C CA  . LYS D 4 136 ? 122.933 112.451 104.349 1.00 47.40  ? 136 LYS R CA  1 
ATOM 5456 C C   . LYS D 4 136 ? 123.082 111.561 103.123 1.00 53.77  ? 136 LYS R C   1 
ATOM 5457 O O   . LYS D 4 136 ? 123.410 112.047 102.032 1.00 59.26  ? 136 LYS R O   1 
ATOM 5458 C CB  . LYS D 4 136 ? 124.195 112.404 105.205 1.00 48.69  ? 136 LYS R CB  1 
ATOM 5459 N N   . ALA D 4 137 ? 122.846 110.257 103.278 1.00 43.80  ? 137 ALA R N   1 
ATOM 5460 C CA  . ALA D 4 137 ? 122.912 109.362 102.129 1.00 50.53  ? 137 ALA R CA  1 
ATOM 5461 C C   . ALA D 4 137 ? 121.853 109.722 101.097 1.00 50.01  ? 137 ALA R C   1 
ATOM 5462 O O   . ALA D 4 137 ? 122.109 109.681 99.885  1.00 51.61  ? 137 ALA R O   1 
ATOM 5463 C CB  . ALA D 4 137 ? 122.755 107.912 102.582 1.00 48.08  ? 137 ALA R CB  1 
ATOM 5464 N N   . ALA D 4 138 ? 120.655 110.078 101.563 1.00 47.84  ? 138 ALA R N   1 
ATOM 5465 C CA  . ALA D 4 138 ? 119.598 110.489 100.651 1.00 53.61  ? 138 ALA R CA  1 
ATOM 5466 C C   . ALA D 4 138 ? 119.989 111.745 99.889  1.00 53.46  ? 138 ALA R C   1 
ATOM 5467 O O   . ALA D 4 138 ? 119.762 111.840 98.677  1.00 58.13  ? 138 ALA R O   1 
ATOM 5468 C CB  . ALA D 4 138 ? 118.297 110.706 101.420 1.00 53.82  ? 138 ALA R CB  1 
ATOM 5469 N N   . VAL D 4 139 ? 120.586 112.719 100.577 1.00 42.80  ? 139 VAL R N   1 
ATOM 5470 C CA  . VAL D 4 139 ? 121.010 113.938 99.894  1.00 37.70  ? 139 VAL R CA  1 
ATOM 5471 C C   . VAL D 4 139 ? 122.088 113.624 98.867  1.00 46.70  ? 139 VAL R C   1 
ATOM 5472 O O   . VAL D 4 139 ? 122.081 114.165 97.753  1.00 55.97  ? 139 VAL R O   1 
ATOM 5473 C CB  . VAL D 4 139 ? 121.477 114.993 100.908 1.00 37.41  ? 139 VAL R CB  1 
ATOM 5474 C CG1 . VAL D 4 139 ? 122.016 116.203 100.189 1.00 45.30  ? 139 VAL R CG1 1 
ATOM 5475 C CG2 . VAL D 4 139 ? 120.324 115.399 101.792 1.00 47.83  ? 139 VAL R CG2 1 
ATOM 5476 N N   . GLY D 4 140 ? 123.014 112.730 99.211  1.00 39.50  ? 140 GLY R N   1 
ATOM 5477 C CA  . GLY D 4 140 ? 124.063 112.380 98.267  1.00 42.50  ? 140 GLY R CA  1 
ATOM 5478 C C   . GLY D 4 140 ? 123.523 111.732 97.006  1.00 51.84  ? 140 GLY R C   1 
ATOM 5479 O O   . GLY D 4 140 ? 123.892 112.111 95.886  1.00 56.16  ? 140 GLY R O   1 
ATOM 5480 N N   . VAL D 4 141 ? 122.628 110.755 97.165  1.00 46.97  ? 141 VAL R N   1 
ATOM 5481 C CA  . VAL D 4 141 ? 122.100 110.070 95.988  1.00 44.00  ? 141 VAL R CA  1 
ATOM 5482 C C   . VAL D 4 141 ? 121.218 111.010 95.173  1.00 46.85  ? 141 VAL R C   1 
ATOM 5483 O O   . VAL D 4 141 ? 121.205 110.955 93.935  1.00 49.29  ? 141 VAL R O   1 
ATOM 5484 C CB  . VAL D 4 141 ? 121.359 108.780 96.384  1.00 43.18  ? 141 VAL R CB  1 
ATOM 5485 C CG1 . VAL D 4 141 ? 122.336 107.769 96.943  1.00 47.16  ? 141 VAL R CG1 1 
ATOM 5486 C CG2 . VAL D 4 141 ? 120.257 109.060 97.370  1.00 42.30  ? 141 VAL R CG2 1 
ATOM 5487 N N   . SER D 4 142 ? 120.477 111.895 95.847  1.00 41.32  ? 142 SER R N   1 
ATOM 5488 C CA  . SER D 4 142 ? 119.680 112.882 95.133  1.00 37.19  ? 142 SER R CA  1 
ATOM 5489 C C   . SER D 4 142 ? 120.562 113.793 94.294  1.00 42.49  ? 142 SER R C   1 
ATOM 5490 O O   . SER D 4 142 ? 120.241 114.093 93.134  1.00 53.61  ? 142 SER R O   1 
ATOM 5491 C CB  . SER D 4 142 ? 118.858 113.696 96.127  1.00 38.23  ? 142 SER R CB  1 
ATOM 5492 O OG  . SER D 4 142 ? 118.097 114.686 95.464  1.00 52.13  ? 142 SER R OG  1 
ATOM 5493 N N   . VAL D 4 143 ? 121.686 114.234 94.857  1.00 37.77  ? 143 VAL R N   1 
ATOM 5494 C CA  . VAL D 4 143 ? 122.593 115.096 94.114  1.00 40.13  ? 143 VAL R CA  1 
ATOM 5495 C C   . VAL D 4 143 ? 123.192 114.349 92.931  1.00 40.79  ? 143 VAL R C   1 
ATOM 5496 O O   . VAL D 4 143 ? 123.382 114.924 91.855  1.00 48.80  ? 143 VAL R O   1 
ATOM 5497 C CB  . VAL D 4 143 ? 123.673 115.663 95.050  1.00 43.61  ? 143 VAL R CB  1 
ATOM 5498 C CG1 . VAL D 4 143 ? 124.869 116.156 94.259  1.00 43.99  ? 143 VAL R CG1 1 
ATOM 5499 C CG2 . VAL D 4 143 ? 123.093 116.783 95.883  1.00 42.73  ? 143 VAL R CG2 1 
ATOM 5500 N N   . VAL D 4 144 ? 123.478 113.056 93.093  1.00 39.13  ? 144 VAL R N   1 
ATOM 5501 C CA  . VAL D 4 144 ? 124.016 112.287 91.970  1.00 36.48  ? 144 VAL R CA  1 
ATOM 5502 C C   . VAL D 4 144 ? 122.996 112.191 90.839  1.00 49.95  ? 144 VAL R C   1 
ATOM 5503 O O   . VAL D 4 144 ? 123.335 112.365 89.657  1.00 54.46  ? 144 VAL R O   1 
ATOM 5504 C CB  . VAL D 4 144 ? 124.472 110.895 92.432  1.00 39.49  ? 144 VAL R CB  1 
ATOM 5505 C CG1 . VAL D 4 144 ? 124.713 110.003 91.229  1.00 41.26  ? 144 VAL R CG1 1 
ATOM 5506 C CG2 . VAL D 4 144 ? 125.728 111.005 93.280  1.00 45.31  ? 144 VAL R CG2 1 
ATOM 5507 N N   . ILE D 4 145 ? 121.733 111.912 91.175  1.00 54.18  ? 145 ILE R N   1 
ATOM 5508 C CA  . ILE D 4 145 ? 120.702 111.816 90.140  1.00 42.33  ? 145 ILE R CA  1 
ATOM 5509 C C   . ILE D 4 145 ? 120.537 113.152 89.423  1.00 46.18  ? 145 ILE R C   1 
ATOM 5510 O O   . ILE D 4 145 ? 120.448 113.211 88.188  1.00 52.16  ? 145 ILE R O   1 
ATOM 5511 C CB  . ILE D 4 145 ? 119.374 111.332 90.744  1.00 32.09  ? 145 ILE R CB  1 
ATOM 5512 C CG1 . ILE D 4 145 ? 119.461 109.856 91.103  1.00 40.47  ? 145 ILE R CG1 1 
ATOM 5513 C CG2 . ILE D 4 145 ? 118.242 111.550 89.776  1.00 41.13  ? 145 ILE R CG2 1 
ATOM 5514 C CD1 . ILE D 4 145 ? 118.380 109.404 92.044  1.00 48.43  ? 145 ILE R CD1 1 
ATOM 5515 N N   . TRP D 4 146 ? 120.513 114.248 90.178  1.00 34.21  ? 146 TRP R N   1 
ATOM 5516 C CA  . TRP D 4 146 ? 120.362 115.545 89.533  1.00 27.88  ? 146 TRP R CA  1 
ATOM 5517 C C   . TRP D 4 146 ? 121.597 115.925 88.727  1.00 36.38  ? 146 TRP R C   1 
ATOM 5518 O O   . TRP D 4 146 ? 121.487 116.659 87.739  1.00 45.15  ? 146 TRP R O   1 
ATOM 5519 C CB  . TRP D 4 146 ? 120.036 116.610 90.570  1.00 22.56  ? 146 TRP R CB  1 
ATOM 5520 C CG  . TRP D 4 146 ? 118.620 116.556 91.011  1.00 20.53  ? 146 TRP R CG  1 
ATOM 5521 C CD1 . TRP D 4 146 ? 118.160 116.151 92.217  1.00 38.44  ? 146 TRP R CD1 1 
ATOM 5522 C CD2 . TRP D 4 146 ? 117.476 116.921 90.246  1.00 26.10  ? 146 TRP R CD2 1 
ATOM 5523 N NE1 . TRP D 4 146 ? 116.795 116.235 92.255  1.00 35.18  ? 146 TRP R NE1 1 
ATOM 5524 C CE2 . TRP D 4 146 ? 116.352 116.711 91.053  1.00 24.87  ? 146 TRP R CE2 1 
ATOM 5525 C CE3 . TRP D 4 146 ? 117.293 117.404 88.951  1.00 45.80  ? 146 TRP R CE3 1 
ATOM 5526 C CZ2 . TRP D 4 146 ? 115.065 116.963 90.612  1.00 37.28  ? 146 TRP R CZ2 1 
ATOM 5527 C CZ3 . TRP D 4 146 ? 116.015 117.656 88.518  1.00 41.76  ? 146 TRP R CZ3 1 
ATOM 5528 C CH2 . TRP D 4 146 ? 114.918 117.435 89.343  1.00 36.28  ? 146 TRP R CH2 1 
ATOM 5529 N N   . ALA D 4 147 ? 122.774 115.433 89.110  1.00 36.89  ? 147 ALA R N   1 
ATOM 5530 C CA  . ALA D 4 147 ? 123.962 115.673 88.301  1.00 39.72  ? 147 ALA R CA  1 
ATOM 5531 C C   . ALA D 4 147 ? 123.890 114.907 86.992  1.00 36.48  ? 147 ALA R C   1 
ATOM 5532 O O   . ALA D 4 147 ? 124.364 115.386 85.957  1.00 49.46  ? 147 ALA R O   1 
ATOM 5533 C CB  . ALA D 4 147 ? 125.219 115.292 89.080  1.00 46.42  ? 147 ALA R CB  1 
ATOM 5534 N N   . LYS D 4 148 ? 123.310 113.708 87.021  1.00 48.36  ? 148 LYS R N   1 
ATOM 5535 C CA  . LYS D 4 148 ? 123.053 112.999 85.771  1.00 55.28  ? 148 LYS R CA  1 
ATOM 5536 C C   . LYS D 4 148 ? 122.100 113.796 84.895  1.00 54.33  ? 148 LYS R C   1 
ATOM 5537 O O   . LYS D 4 148 ? 122.290 113.894 83.675  1.00 55.38  ? 148 LYS R O   1 
ATOM 5538 C CB  . LYS D 4 148 ? 122.487 111.608 86.051  1.00 51.46  ? 148 LYS R CB  1 
ATOM 5539 N N   . GLU D 4 149 ? 121.072 114.381 85.511  1.00 61.73  ? 149 GLU R N   1 
ATOM 5540 C CA  . GLU D 4 149 ? 120.169 115.265 84.778  1.00 61.41  ? 149 GLU R CA  1 
ATOM 5541 C C   . GLU D 4 149 ? 120.929 116.422 84.141  1.00 57.42  ? 149 GLU R C   1 
ATOM 5542 O O   . GLU D 4 149 ? 120.718 116.748 82.971  1.00 62.17  ? 149 GLU R O   1 
ATOM 5543 C CB  . GLU D 4 149 ? 119.079 115.791 85.712  1.00 60.09  ? 149 GLU R CB  1 
ATOM 5544 C CG  . GLU D 4 149 ? 118.001 116.607 85.020  1.00 58.62  ? 149 GLU R CG  1 
ATOM 5545 C CD  . GLU D 4 149 ? 117.613 116.039 83.677  1.00 66.88  ? 149 GLU R CD  1 
ATOM 5546 O OE1 . GLU D 4 149 ? 117.037 114.932 83.644  1.00 68.33  ? 149 GLU R OE1 1 
ATOM 5547 O OE2 . GLU D 4 149 ? 117.879 116.699 82.652  1.00 66.58  ? 149 GLU R OE2 1 
ATOM 5548 N N   . LEU D 4 150 ? 121.832 117.046 84.898  1.00 52.37  ? 150 LEU R N   1 
ATOM 5549 C CA  . LEU D 4 150 ? 122.565 118.203 84.391  1.00 51.11  ? 150 LEU R CA  1 
ATOM 5550 C C   . LEU D 4 150 ? 123.532 117.826 83.278  1.00 50.38  ? 150 LEU R C   1 
ATOM 5551 O O   . LEU D 4 150 ? 123.734 118.609 82.347  1.00 58.53  ? 150 LEU R O   1 
ATOM 5552 C CB  . LEU D 4 150 ? 123.318 118.891 85.528  1.00 52.96  ? 150 LEU R CB  1 
ATOM 5553 N N   . LEU D 4 151 ? 124.143 116.645 83.350  1.00 54.63  ? 151 LEU R N   1 
ATOM 5554 C CA  . LEU D 4 151 ? 125.040 116.229 82.277  1.00 53.15  ? 151 LEU R CA  1 
ATOM 5555 C C   . LEU D 4 151 ? 124.264 115.889 81.008  1.00 64.37  ? 151 LEU R C   1 
ATOM 5556 O O   . LEU D 4 151 ? 124.657 116.289 79.903  1.00 73.64  ? 151 LEU R O   1 
ATOM 5557 C CB  . LEU D 4 151 ? 125.888 115.045 82.730  1.00 56.84  ? 151 LEU R CB  1 
ATOM 5558 C CG  . LEU D 4 151 ? 126.924 114.556 81.722  1.00 63.29  ? 151 LEU R CG  1 
ATOM 5559 C CD1 . LEU D 4 151 ? 127.937 115.649 81.441  1.00 59.45  ? 151 LEU R CD1 1 
ATOM 5560 C CD2 . LEU D 4 151 ? 127.613 113.299 82.229  1.00 62.83  ? 151 LEU R CD2 1 
ATOM 5561 N N   . THR D 4 152 ? 123.145 115.172 81.135  1.00 64.20  ? 152 THR R N   1 
ATOM 5562 C CA  . THR D 4 152 ? 122.305 114.966 79.960  1.00 59.39  ? 152 THR R CA  1 
ATOM 5563 C C   . THR D 4 152 ? 121.787 116.290 79.412  1.00 59.13  ? 152 THR R C   1 
ATOM 5564 O O   . THR D 4 152 ? 121.587 116.426 78.202  1.00 59.71  ? 152 THR R O   1 
ATOM 5565 C CB  . THR D 4 152 ? 121.139 114.036 80.289  1.00 61.85  ? 152 THR R CB  1 
ATOM 5566 O OG1 . THR D 4 152 ? 120.326 114.626 81.309  1.00 61.92  ? 152 THR R OG1 1 
ATOM 5567 C CG2 . THR D 4 152 ? 121.646 112.687 80.762  1.00 61.19  ? 152 THR R CG2 1 
ATOM 5568 N N   . SER D 4 153 ? 121.573 117.278 80.283  1.00 61.55  ? 153 SER R N   1 
ATOM 5569 C CA  . SER D 4 153 ? 121.084 118.577 79.845  1.00 58.92  ? 153 SER R CA  1 
ATOM 5570 C C   . SER D 4 153 ? 122.166 119.412 79.180  1.00 62.37  ? 153 SER R C   1 
ATOM 5571 O O   . SER D 4 153 ? 121.850 120.256 78.341  1.00 66.90  ? 153 SER R O   1 
ATOM 5572 C CB  . SER D 4 153 ? 120.492 119.343 81.026  1.00 65.85  ? 153 SER R CB  1 
ATOM 5573 O OG  . SER D 4 153 ? 120.339 120.716 80.716  1.00 68.95  ? 153 SER R OG  1 
ATOM 5574 N N   . ILE D 4 154 ? 123.432 119.240 79.565  1.00 68.93  ? 154 ILE R N   1 
ATOM 5575 C CA  . ILE D 4 154 ? 124.497 119.891 78.808  1.00 69.09  ? 154 ILE R CA  1 
ATOM 5576 C C   . ILE D 4 154 ? 124.718 119.144 77.503  1.00 61.31  ? 154 ILE R C   1 
ATOM 5577 O O   . ILE D 4 154 ? 125.288 119.694 76.556  1.00 60.67  ? 154 ILE R O   1 
ATOM 5578 C CB  . ILE D 4 154 ? 125.799 120.012 79.625  1.00 65.06  ? 154 ILE R CB  1 
ATOM 5579 N N   . TYR D 4 155 ? 124.272 117.895 77.435  1.00 64.54  ? 155 TYR R N   1 
ATOM 5580 C CA  . TYR D 4 155 ? 124.029 117.251 76.156  1.00 68.61  ? 155 TYR R CA  1 
ATOM 5581 C C   . TYR D 4 155 ? 122.707 117.774 75.590  1.00 77.37  ? 155 TYR R C   1 
ATOM 5582 O O   . TYR D 4 155 ? 122.009 118.568 76.224  1.00 81.76  ? 155 TYR R O   1 
ATOM 5583 C CB  . TYR D 4 155 ? 124.028 115.734 76.326  1.00 75.70  ? 155 TYR R CB  1 
ATOM 5584 C CG  . TYR D 4 155 ? 124.145 114.950 75.041  1.00 76.13  ? 155 TYR R CG  1 
ATOM 5585 C CD1 . TYR D 4 155 ? 124.952 115.390 74.006  1.00 73.20  ? 155 TYR R CD1 1 
ATOM 5586 C CD2 . TYR D 4 155 ? 123.458 113.755 74.873  1.00 77.71  ? 155 TYR R CD2 1 
ATOM 5587 C CE1 . TYR D 4 155 ? 125.062 114.669 72.837  1.00 76.70  ? 155 TYR R CE1 1 
ATOM 5588 C CE2 . TYR D 4 155 ? 123.564 113.029 73.706  1.00 75.80  ? 155 TYR R CE2 1 
ATOM 5589 C CZ  . TYR D 4 155 ? 124.366 113.489 72.694  1.00 76.06  ? 155 TYR R CZ  1 
ATOM 5590 O OH  . TYR D 4 155 ? 124.473 112.767 71.532  1.00 78.32  ? 155 TYR R OH  1 
ATOM 5591 N N   . PHE D 4 156 ? 122.354 117.334 74.381  1.00 79.18  ? 156 PHE R N   1 
ATOM 5592 C CA  . PHE D 4 156 ? 121.178 117.776 73.627  1.00 76.59  ? 156 PHE R CA  1 
ATOM 5593 C C   . PHE D 4 156 ? 121.253 119.226 73.168  1.00 76.81  ? 156 PHE R C   1 
ATOM 5594 O O   . PHE D 4 156 ? 120.291 119.721 72.568  1.00 81.09  ? 156 PHE R O   1 
ATOM 5595 C CB  . PHE D 4 156 ? 119.864 117.601 74.401  1.00 73.10  ? 156 PHE R CB  1 
ATOM 5596 C CG  . PHE D 4 156 ? 119.475 116.181 74.642  1.00 70.97  ? 156 PHE R CG  1 
ATOM 5597 C CD1 . PHE D 4 156 ? 118.866 115.445 73.651  1.00 78.13  ? 156 PHE R CD1 1 
ATOM 5598 C CD2 . PHE D 4 156 ? 119.671 115.597 75.876  1.00 73.26  ? 156 PHE R CD2 1 
ATOM 5599 C CE1 . PHE D 4 156 ? 118.490 114.142 73.873  1.00 81.89  ? 156 PHE R CE1 1 
ATOM 5600 C CE2 . PHE D 4 156 ? 119.295 114.292 76.105  1.00 76.35  ? 156 PHE R CE2 1 
ATOM 5601 C CZ  . PHE D 4 156 ? 118.704 113.564 75.103  1.00 79.96  ? 156 PHE R CZ  1 
ATOM 5602 N N   . LEU D 4 157 ? 122.351 119.927 73.426  1.00 72.88  ? 157 LEU R N   1 
ATOM 5603 C CA  . LEU D 4 157 ? 122.505 121.302 72.978  1.00 75.57  ? 157 LEU R CA  1 
ATOM 5604 C C   . LEU D 4 157 ? 123.611 121.504 71.959  1.00 76.72  ? 157 LEU R C   1 
ATOM 5605 O O   . LEU D 4 157 ? 123.682 122.584 71.363  1.00 77.63  ? 157 LEU R O   1 
ATOM 5606 C CB  . LEU D 4 157 ? 122.747 122.242 74.168  1.00 73.68  ? 157 LEU R CB  1 
ATOM 5607 C CG  . LEU D 4 157 ? 121.523 122.649 74.982  1.00 74.64  ? 157 LEU R CG  1 
ATOM 5608 C CD1 . LEU D 4 157 ? 120.973 121.523 75.793  1.00 71.66  ? 157 LEU R CD1 1 
ATOM 5609 C CD2 . LEU D 4 157 ? 121.891 123.807 75.883  1.00 77.67  ? 157 LEU R CD2 1 
ATOM 5610 N N   . MET D 4 158 ? 124.469 120.514 71.736  1.00 88.12  ? 158 MET R N   1 
ATOM 5611 C CA  . MET D 4 158 ? 125.444 120.633 70.664  1.00 91.12  ? 158 MET R CA  1 
ATOM 5612 C C   . MET D 4 158 ? 124.821 120.425 69.291  1.00 94.22  ? 158 MET R C   1 
ATOM 5613 O O   . MET D 4 158 ? 125.506 120.627 68.282  1.00 93.25  ? 158 MET R O   1 
ATOM 5614 C CB  . MET D 4 158 ? 126.584 119.637 70.879  1.00 89.46  ? 158 MET R CB  1 
ATOM 5615 N N   . HIS D 4 159 ? 123.552 120.029 69.228  1.00 92.90  ? 159 HIS R N   1 
ATOM 5616 C CA  . HIS D 4 159 ? 122.876 119.723 67.975  1.00 90.04  ? 159 HIS R CA  1 
ATOM 5617 C C   . HIS D 4 159 ? 121.752 120.720 67.732  1.00 92.11  ? 159 HIS R C   1 
ATOM 5618 O O   . HIS D 4 159 ? 120.853 120.863 68.566  1.00 91.54  ? 159 HIS R O   1 
ATOM 5619 C CB  . HIS D 4 159 ? 122.329 118.296 67.996  1.00 88.72  ? 159 HIS R CB  1 
ATOM 5620 C CG  . HIS D 4 159 ? 123.392 117.247 68.093  1.00 93.52  ? 159 HIS R CG  1 
ATOM 5621 N ND1 . HIS D 4 159 ? 123.149 115.914 67.840  1.00 96.45  ? 159 HIS R ND1 1 
ATOM 5622 C CD2 . HIS D 4 159 ? 124.706 117.336 68.406  1.00 94.13  ? 159 HIS R CD2 1 
ATOM 5623 C CE1 . HIS D 4 159 ? 124.267 115.228 67.996  1.00 95.75  ? 159 HIS R CE1 1 
ATOM 5624 N NE2 . HIS D 4 159 ? 125.226 116.067 68.341  1.00 95.99  ? 159 HIS R NE2 1 
ATOM 5625 N N   . GLU D 4 160 ? 121.803 121.399 66.587  1.00 90.63  ? 160 GLU R N   1 
ATOM 5626 C CA  . GLU D 4 160 ? 120.799 122.395 66.226  1.00 88.38  ? 160 GLU R CA  1 
ATOM 5627 C C   . GLU D 4 160 ? 119.588 121.675 65.654  1.00 87.73  ? 160 GLU R C   1 
ATOM 5628 O O   . GLU D 4 160 ? 119.643 121.137 64.543  1.00 91.51  ? 160 GLU R O   1 
ATOM 5629 C CB  . GLU D 4 160 ? 121.369 123.392 65.224  1.00 86.94  ? 160 GLU R CB  1 
ATOM 5630 N N   . GLU D 4 161 ? 118.493 121.663 66.406  1.00 84.04  ? 161 GLU R N   1 
ATOM 5631 C CA  . GLU D 4 161 ? 117.328 120.845 66.087  1.00 85.16  ? 161 GLU R CA  1 
ATOM 5632 C C   . GLU D 4 161 ? 116.058 121.692 65.943  1.00 90.97  ? 161 GLU R C   1 
ATOM 5633 O O   . GLU D 4 161 ? 115.196 121.731 66.822  1.00 91.13  ? 161 GLU R O   1 
ATOM 5634 C CB  . GLU D 4 161 ? 117.236 119.763 67.179  1.00 81.05  ? 161 GLU R CB  1 
ATOM 5635 C CG  . GLU D 4 161 ? 116.988 120.303 68.567  1.00 84.26  ? 161 GLU R CG  1 
ATOM 5636 C CD  . GLU D 4 161 ? 116.978 119.234 69.619  1.00 88.03  ? 161 GLU R CD  1 
ATOM 5637 O OE1 . GLU D 4 161 ? 117.181 118.053 69.275  1.00 92.41  ? 161 GLU R OE1 1 
ATOM 5638 O OE2 . GLU D 4 161 ? 116.806 119.585 70.802  1.00 86.75  ? 161 GLU R OE2 1 
ATOM 5639 N N   . VAL D 4 162 ? 115.924 122.323 64.777  1.00 90.07  ? 162 VAL R N   1 
ATOM 5640 C CA  . VAL D 4 162 ? 114.691 122.951 64.303  1.00 83.58  ? 162 VAL R CA  1 
ATOM 5641 C C   . VAL D 4 162 ? 114.728 122.913 62.783  1.00 88.28  ? 162 VAL R C   1 
ATOM 5642 O O   . VAL D 4 162 ? 115.704 123.358 62.172  1.00 89.37  ? 162 VAL R O   1 
ATOM 5643 C CB  . VAL D 4 162 ? 114.511 124.411 64.772  1.00 84.00  ? 162 VAL R CB  1 
ATOM 5644 C CG1 . VAL D 4 162 ? 113.270 125.007 64.135  1.00 87.48  ? 162 VAL R CG1 1 
ATOM 5645 C CG2 . VAL D 4 162 ? 114.399 124.519 66.277  1.00 84.04  ? 162 VAL R CG2 1 
ATOM 5646 N N   . ILE D 4 163 ? 113.675 122.387 62.167  1.00 88.50  ? 163 ILE R N   1 
ATOM 5647 C CA  . ILE D 4 163 ? 113.605 122.297 60.715  1.00 86.80  ? 163 ILE R CA  1 
ATOM 5648 C C   . ILE D 4 163 ? 112.278 122.875 60.252  1.00 87.87  ? 163 ILE R C   1 
ATOM 5649 O O   . ILE D 4 163 ? 111.296 122.906 61.000  1.00 89.61  ? 163 ILE R O   1 
ATOM 5650 C CB  . ILE D 4 163 ? 113.775 120.845 60.215  1.00 90.60  ? 163 ILE R CB  1 
ATOM 5651 N N   . GLU D 4 164 ? 112.255 123.341 59.009  1.00 95.92  ? 164 GLU R N   1 
ATOM 5652 C CA  . GLU D 4 164 ? 111.063 123.916 58.410  1.00 98.54  ? 164 GLU R CA  1 
ATOM 5653 C C   . GLU D 4 164 ? 110.334 122.876 57.567  1.00 99.75  ? 164 GLU R C   1 
ATOM 5654 O O   . GLU D 4 164 ? 110.944 121.971 56.992  1.00 99.57  ? 164 GLU R O   1 
ATOM 5655 C CB  . GLU D 4 164 ? 111.417 125.129 57.550  1.00 97.72  ? 164 GLU R CB  1 
ATOM 5656 N N   . ASP D 4 165 ? 109.017 123.019 57.504  1.00 106.00 ? 165 ASP R N   1 
ATOM 5657 C CA  . ASP D 4 165 ? 108.139 122.135 56.755  1.00 105.53 ? 165 ASP R CA  1 
ATOM 5658 C C   . ASP D 4 165 ? 107.868 122.724 55.375  1.00 104.39 ? 165 ASP R C   1 
ATOM 5659 O O   . ASP D 4 165 ? 108.068 123.918 55.138  1.00 104.83 ? 165 ASP R O   1 
ATOM 5660 C CB  . ASP D 4 165 ? 106.831 121.921 57.528  1.00 104.93 ? 165 ASP R CB  1 
ATOM 5661 N N   . GLU D 4 166 ? 107.434 121.859 54.451  1.00 102.54 ? 166 GLU R N   1 
ATOM 5662 C CA  . GLU D 4 166 ? 107.080 122.312 53.109  1.00 103.81 ? 166 GLU R CA  1 
ATOM 5663 C C   . GLU D 4 166 ? 106.086 123.464 53.172  1.00 104.59 ? 166 GLU R C   1 
ATOM 5664 O O   . GLU D 4 166 ? 106.269 124.497 52.519  1.00 104.27 ? 166 GLU R O   1 
ATOM 5665 C CB  . GLU D 4 166 ? 106.513 121.149 52.295  1.00 103.01 ? 166 GLU R CB  1 
ATOM 5666 N N   . ASN D 4 167 ? 105.027 123.303 53.957  1.00 99.64  ? 167 ASN R N   1 
ATOM 5667 C CA  . ASN D 4 167 ? 104.216 124.434 54.389  1.00 99.49  ? 167 ASN R CA  1 
ATOM 5668 C C   . ASN D 4 167 ? 104.886 125.015 55.627  1.00 99.95  ? 167 ASN R C   1 
ATOM 5669 O O   . ASN D 4 167 ? 104.984 124.340 56.655  1.00 100.18 ? 167 ASN R O   1 
ATOM 5670 C CB  . ASN D 4 167 ? 102.782 123.999 54.675  1.00 102.41 ? 167 ASN R CB  1 
ATOM 5671 N N   . GLN D 4 168 ? 105.391 126.245 55.519  1.00 97.39  ? 168 GLN R N   1 
ATOM 5672 C CA  . GLN D 4 168 ? 106.269 126.797 56.546  1.00 99.80  ? 168 GLN R CA  1 
ATOM 5673 C C   . GLN D 4 168 ? 105.678 126.692 57.946  1.00 100.95 ? 168 GLN R C   1 
ATOM 5674 O O   . GLN D 4 168 ? 104.709 127.382 58.275  1.00 103.59 ? 168 GLN R O   1 
ATOM 5675 C CB  . GLN D 4 168 ? 106.594 128.257 56.228  1.00 98.52  ? 168 GLN R CB  1 
ATOM 5676 N N   . HIS D 4 169 ? 106.340 125.865 58.748  1.00 94.73  ? 169 HIS R N   1 
ATOM 5677 C CA  . HIS D 4 169 ? 106.021 125.621 60.144  1.00 93.27  ? 169 HIS R CA  1 
ATOM 5678 C C   . HIS D 4 169 ? 107.342 125.384 60.889  1.00 95.41  ? 169 HIS R C   1 
ATOM 5679 O O   . HIS D 4 169 ? 108.425 125.465 60.304  1.00 98.41  ? 169 HIS R O   1 
ATOM 5680 C CB  . HIS D 4 169 ? 105.104 124.407 60.286  1.00 93.02  ? 169 HIS R CB  1 
ATOM 5681 C CG  . HIS D 4 169 ? 103.703 124.650 59.820  1.00 97.03  ? 169 HIS R CG  1 
ATOM 5682 N ND1 . HIS D 4 169 ? 103.127 123.937 58.790  1.00 98.46  ? 169 HIS R ND1 1 
ATOM 5683 C CD2 . HIS D 4 169 ? 102.761 125.527 60.242  1.00 97.57  ? 169 HIS R CD2 1 
ATOM 5684 C CE1 . HIS D 4 169 ? 101.891 124.364 58.599  1.00 98.68  ? 169 HIS R CE1 1 
ATOM 5685 N NE2 . HIS D 4 169 ? 101.645 125.329 59.466  1.00 99.54  ? 169 HIS R NE2 1 
ATOM 5686 N N   . ARG D 4 170 ? 107.256 125.093 62.180  1.00 83.98  ? 170 ARG R N   1 
ATOM 5687 C CA  . ARG D 4 170 ? 108.451 124.843 62.985  1.00 84.84  ? 170 ARG R CA  1 
ATOM 5688 C C   . ARG D 4 170 ? 108.186 123.635 63.877  1.00 86.06  ? 170 ARG R C   1 
ATOM 5689 O O   . ARG D 4 170 ? 107.466 123.738 64.873  1.00 87.65  ? 170 ARG R O   1 
ATOM 5690 C CB  . ARG D 4 170 ? 108.819 126.070 63.809  1.00 85.27  ? 170 ARG R CB  1 
ATOM 5691 N N   . VAL D 4 171 ? 108.769 122.496 63.518  1.00 78.27  ? 171 VAL R N   1 
ATOM 5692 C CA  . VAL D 4 171 ? 108.695 121.304 64.353  1.00 72.54  ? 171 VAL R CA  1 
ATOM 5693 C C   . VAL D 4 171 ? 109.702 121.441 65.482  1.00 78.46  ? 171 VAL R C   1 
ATOM 5694 O O   . VAL D 4 171 ? 110.743 122.091 65.335  1.00 85.60  ? 171 VAL R O   1 
ATOM 5695 C CB  . VAL D 4 171 ? 108.944 120.038 63.514  1.00 75.96  ? 171 VAL R CB  1 
ATOM 5696 C CG1 . VAL D 4 171 ? 107.877 119.901 62.450  1.00 75.99  ? 171 VAL R CG1 1 
ATOM 5697 C CG2 . VAL D 4 171 ? 110.319 120.092 62.879  1.00 80.53  ? 171 VAL R CG2 1 
ATOM 5698 N N   . CYS D 4 172 ? 109.403 120.833 66.627  1.00 75.56  ? 172 CYS R N   1 
ATOM 5699 C CA  . CYS D 4 172 ? 110.153 121.187 67.827  1.00 77.01  ? 172 CYS R CA  1 
ATOM 5700 C C   . CYS D 4 172 ? 111.350 120.275 68.078  1.00 74.70  ? 172 CYS R C   1 
ATOM 5701 O O   . CYS D 4 172 ? 112.497 120.728 68.034  1.00 78.31  ? 172 CYS R O   1 
ATOM 5702 C CB  . CYS D 4 172 ? 109.223 121.175 69.044  1.00 82.33  ? 172 CYS R CB  1 
ATOM 5703 S SG  . CYS D 4 172 ? 110.026 121.668 70.584  1.00 93.06  ? 172 CYS R SG  1 
ATOM 5704 N N   . PHE D 4 173 ? 111.105 118.994 68.338  1.00 68.02  ? 173 PHE R N   1 
ATOM 5705 C CA  . PHE D 4 173 ? 112.167 118.131 68.837  1.00 71.15  ? 173 PHE R CA  1 
ATOM 5706 C C   . PHE D 4 173 ? 112.074 116.755 68.178  1.00 73.91  ? 173 PHE R C   1 
ATOM 5707 O O   . PHE D 4 173 ? 112.280 115.720 68.815  1.00 79.43  ? 173 PHE R O   1 
ATOM 5708 C CB  . PHE D 4 173 ? 112.099 118.068 70.369  1.00 74.57  ? 173 PHE R CB  1 
ATOM 5709 C CG  . PHE D 4 173 ? 113.183 117.253 71.021  1.00 72.04  ? 173 PHE R CG  1 
ATOM 5710 C CD1 . PHE D 4 173 ? 114.459 117.757 71.123  1.00 74.81  ? 173 PHE R CD1 1 
ATOM 5711 C CD2 . PHE D 4 173 ? 112.910 116.026 71.601  1.00 71.13  ? 173 PHE R CD2 1 
ATOM 5712 C CE1 . PHE D 4 173 ? 115.456 117.040 71.734  1.00 75.90  ? 173 PHE R CE1 1 
ATOM 5713 C CE2 . PHE D 4 173 ? 113.912 115.301 72.214  1.00 72.46  ? 173 PHE R CE2 1 
ATOM 5714 C CZ  . PHE D 4 173 ? 115.186 115.812 72.282  1.00 74.23  ? 173 PHE R CZ  1 
ATOM 5715 N N   . GLU D 4 174 ? 111.765 116.722 66.883  1.00 83.15  ? 174 GLU R N   1 
ATOM 5716 C CA  . GLU D 4 174 ? 111.557 115.457 66.191  1.00 84.64  ? 174 GLU R CA  1 
ATOM 5717 C C   . GLU D 4 174 ? 112.005 115.582 64.744  1.00 87.02  ? 174 GLU R C   1 
ATOM 5718 O O   . GLU D 4 174 ? 112.125 116.682 64.200  1.00 91.49  ? 174 GLU R O   1 
ATOM 5719 C CB  . GLU D 4 174 ? 110.089 115.014 66.228  1.00 87.77  ? 174 GLU R CB  1 
ATOM 5720 C CG  . GLU D 4 174 ? 109.561 114.632 67.596  1.00 90.58  ? 174 GLU R CG  1 
ATOM 5721 C CD  . GLU D 4 174 ? 108.056 114.464 67.607  1.00 91.17  ? 174 GLU R CD  1 
ATOM 5722 O OE1 . GLU D 4 174 ? 107.426 114.681 66.550  1.00 90.33  ? 174 GLU R OE1 1 
ATOM 5723 O OE2 . GLU D 4 174 ? 107.502 114.116 68.671  1.00 92.63  ? 174 GLU R OE2 1 
ATOM 5724 N N   . HIS D 4 175 ? 112.571 114.506 64.300  1.00 97.33  ? 175 HIS R N   1 
ATOM 5725 C CA  . HIS D 4 175 ? 113.114 114.377 62.992  1.00 100.99 ? 175 HIS R CA  1 
ATOM 5726 C C   . HIS D 4 175 ? 112.569 113.048 62.674  1.00 101.51 ? 175 HIS R C   1 
ATOM 5727 O O   . HIS D 4 175 ? 112.724 112.053 63.395  1.00 101.62 ? 175 HIS R O   1 
ATOM 5728 C CB  . HIS D 4 175 ? 114.600 114.299 63.033  1.00 100.66 ? 175 HIS R CB  1 
ATOM 5729 N N   . TYR D 4 176 ? 111.884 113.011 61.526  1.00 97.94  ? 176 TYR R N   1 
ATOM 5730 C CA  . TYR D 4 176 ? 111.234 111.780 61.090  1.00 98.83  ? 176 TYR R CA  1 
ATOM 5731 C C   . TYR D 4 176 ? 112.186 110.742 60.525  1.00 102.87 ? 176 TYR R C   1 
ATOM 5732 O O   . TYR D 4 176 ? 112.328 109.666 61.102  1.00 103.82 ? 176 TYR R O   1 
ATOM 5733 C CB  . TYR D 4 176 ? 110.143 112.094 60.058  1.00 30.00  ? 176 TYR R CB  1 
ATOM 5734 C CG  . TYR D 4 176 ? 108.962 112.847 60.625  1.00 30.00  ? 176 TYR R CG  1 
ATOM 5735 C CD1 . TYR D 4 176 ? 108.630 112.747 61.969  1.00 30.00  ? 176 TYR R CD1 1 
ATOM 5736 C CD2 . TYR D 4 176 ? 108.178 113.656 59.814  1.00 30.00  ? 176 TYR R CD2 1 
ATOM 5737 C CE1 . TYR D 4 176 ? 107.550 113.433 62.491  1.00 30.00  ? 176 TYR R CE1 1 
ATOM 5738 C CE2 . TYR D 4 176 ? 107.097 114.346 60.327  1.00 30.00  ? 176 TYR R CE2 1 
ATOM 5739 C CZ  . TYR D 4 176 ? 106.787 114.231 61.664  1.00 30.00  ? 176 TYR R CZ  1 
ATOM 5740 O OH  . TYR D 4 176 ? 105.710 114.918 62.175  1.00 30.00  ? 176 TYR R OH  1 
ATOM 5741 N N   . PRO D 4 177 ? 112.834 110.990 59.382  1.00 95.91  ? 177 PRO R N   1 
ATOM 5742 C CA  . PRO D 4 177 ? 113.748 109.900 59.011  1.00 95.05  ? 177 PRO R CA  1 
ATOM 5743 C C   . PRO D 4 177 ? 114.746 109.881 60.142  1.00 96.80  ? 177 PRO R C   1 
ATOM 5744 O O   . PRO D 4 177 ? 115.612 110.756 60.166  1.00 99.15  ? 177 PRO R O   1 
ATOM 5745 C CB  . PRO D 4 177 ? 114.377 110.382 57.711  1.00 88.94  ? 177 PRO R CB  1 
ATOM 5746 C CG  . PRO D 4 177 ? 114.231 111.865 57.727  1.00 90.30  ? 177 PRO R CG  1 
ATOM 5747 C CD  . PRO D 4 177 ? 112.969 112.154 58.481  1.00 92.18  ? 177 PRO R CD  1 
ATOM 5748 N N   . ILE D 4 178 ? 114.655 108.938 61.093  1.00 92.10  ? 178 ILE R N   1 
ATOM 5749 C CA  . ILE D 4 178 ? 115.584 109.090 62.207  1.00 90.72  ? 178 ILE R CA  1 
ATOM 5750 C C   . ILE D 4 178 ? 117.042 109.296 61.839  1.00 92.14  ? 178 ILE R C   1 
ATOM 5751 O O   . ILE D 4 178 ? 117.559 108.635 60.960  1.00 92.45  ? 178 ILE R O   1 
ATOM 5752 C CB  . ILE D 4 178 ? 115.384 108.057 63.293  1.00 92.39  ? 178 ILE R CB  1 
ATOM 5753 C CG1 . ILE D 4 178 ? 113.918 107.839 63.515  1.00 91.36  ? 178 ILE R CG1 1 
ATOM 5754 C CG2 . ILE D 4 178 ? 115.836 108.619 64.597  1.00 94.19  ? 178 ILE R CG2 1 
ATOM 5755 C CD1 . ILE D 4 178 ? 113.248 108.978 64.241  1.00 91.35  ? 178 ILE R CD1 1 
ATOM 5756 N N   . GLN D 4 179 ? 117.680 110.260 62.499  1.00 99.71  ? 179 GLN R N   1 
ATOM 5757 C CA  . GLN D 4 179 ? 119.066 110.605 62.240  1.00 101.18 ? 179 GLN R CA  1 
ATOM 5758 C C   . GLN D 4 179 ? 119.988 109.526 62.797  1.00 103.09 ? 179 GLN R C   1 
ATOM 5759 O O   . GLN D 4 179 ? 119.619 108.749 63.681  1.00 104.98 ? 179 GLN R O   1 
ATOM 5760 C CB  . GLN D 4 179 ? 119.404 111.961 62.855  1.00 99.44  ? 179 GLN R CB  1 
ATOM 5761 N N   . ALA D 4 180 ? 121.206 109.480 62.255  1.00 98.46  ? 180 ALA R N   1 
ATOM 5762 C CA  . ALA D 4 180 ? 122.167 108.472 62.688  1.00 97.12  ? 180 ALA R CA  1 
ATOM 5763 C C   . ALA D 4 180 ? 122.517 108.637 64.160  1.00 95.99  ? 180 ALA R C   1 
ATOM 5764 O O   . ALA D 4 180 ? 122.627 107.649 64.895  1.00 95.44  ? 180 ALA R O   1 
ATOM 5765 C CB  . ALA D 4 180 ? 123.426 108.541 61.824  1.00 95.59  ? 180 ALA R CB  1 
ATOM 5766 N N   . TRP D 4 181 ? 122.691 109.877 64.612  1.00 88.23  ? 181 TRP R N   1 
ATOM 5767 C CA  . TRP D 4 181 ? 123.114 110.125 65.983  1.00 89.08  ? 181 TRP R CA  1 
ATOM 5768 C C   . TRP D 4 181 ? 122.035 109.822 67.011  1.00 88.24  ? 181 TRP R C   1 
ATOM 5769 O O   . TRP D 4 181 ? 122.342 109.784 68.207  1.00 92.32  ? 181 TRP R O   1 
ATOM 5770 C CB  . TRP D 4 181 ? 123.568 111.575 66.137  1.00 91.41  ? 181 TRP R CB  1 
ATOM 5771 C CG  . TRP D 4 181 ? 122.441 112.552 66.249  1.00 90.75  ? 181 TRP R CG  1 
ATOM 5772 C CD1 . TRP D 4 181 ? 121.748 113.120 65.224  1.00 92.21  ? 181 TRP R CD1 1 
ATOM 5773 C CD2 . TRP D 4 181 ? 121.874 113.075 67.454  1.00 86.95  ? 181 TRP R CD2 1 
ATOM 5774 N NE1 . TRP D 4 181 ? 120.788 113.967 65.714  1.00 91.40  ? 181 TRP R NE1 1 
ATOM 5775 C CE2 . TRP D 4 181 ? 120.845 113.957 67.082  1.00 86.90  ? 181 TRP R CE2 1 
ATOM 5776 C CE3 . TRP D 4 181 ? 122.139 112.884 68.811  1.00 89.62  ? 181 TRP R CE3 1 
ATOM 5777 C CZ2 . TRP D 4 181 ? 120.081 114.644 68.016  1.00 87.44  ? 181 TRP R CZ2 1 
ATOM 5778 C CZ3 . TRP D 4 181 ? 121.379 113.569 69.736  1.00 89.87  ? 181 TRP R CZ3 1 
ATOM 5779 C CH2 . TRP D 4 181 ? 120.362 114.436 69.335  1.00 89.18  ? 181 TRP R CH2 1 
ATOM 5780 N N   . GLN D 4 182 ? 120.792 109.608 66.590  1.00 86.69  ? 182 GLN R N   1 
ATOM 5781 C CA  . GLN D 4 182 ? 119.717 109.373 67.542  1.00 90.13  ? 182 GLN R CA  1 
ATOM 5782 C C   . GLN D 4 182 ? 119.463 107.892 67.788  1.00 90.57  ? 182 GLN R C   1 
ATOM 5783 O O   . GLN D 4 182 ? 118.870 107.540 68.813  1.00 94.74  ? 182 GLN R O   1 
ATOM 5784 C CB  . GLN D 4 182 ? 118.436 110.061 67.053  1.00 91.67  ? 182 GLN R CB  1 
ATOM 5785 C CG  . GLN D 4 182 ? 117.255 109.983 68.002  1.00 90.03  ? 182 GLN R CG  1 
ATOM 5786 C CD  . GLN D 4 182 ? 116.046 110.734 67.483  1.00 93.11  ? 182 GLN R CD  1 
ATOM 5787 O OE1 . GLN D 4 182 ? 116.071 111.290 66.386  1.00 95.73  ? 182 GLN R OE1 1 
ATOM 5788 N NE2 . GLN D 4 182 ? 114.977 110.753 68.271  1.00 92.84  ? 182 GLN R NE2 1 
ATOM 5789 N N   . ARG D 4 183 ? 119.919 107.018 66.889  1.00 82.08  ? 183 ARG R N   1 
ATOM 5790 C CA  . ARG D 4 183 ? 119.700 105.586 67.068  1.00 83.50  ? 183 ARG R CA  1 
ATOM 5791 C C   . ARG D 4 183 ? 120.426 105.064 68.302  1.00 82.32  ? 183 ARG R C   1 
ATOM 5792 O O   . ARG D 4 183 ? 119.870 104.281 69.086  1.00 87.43  ? 183 ARG R O   1 
ATOM 5793 C CB  . ARG D 4 183 ? 120.151 104.833 65.817  1.00 84.03  ? 183 ARG R CB  1 
ATOM 5794 N N   . ALA D 4 184 ? 121.679 105.482 68.486  1.00 78.72  ? 184 ALA R N   1 
ATOM 5795 C CA  . ALA D 4 184 ? 122.434 105.045 69.653  1.00 84.16  ? 184 ALA R CA  1 
ATOM 5796 C C   . ALA D 4 184 ? 121.796 105.560 70.933  1.00 83.49  ? 184 ALA R C   1 
ATOM 5797 O O   . ALA D 4 184 ? 121.744 104.846 71.945  1.00 86.94  ? 184 ALA R O   1 
ATOM 5798 C CB  . ALA D 4 184 ? 123.885 105.511 69.546  1.00 83.53  ? 184 ALA R CB  1 
ATOM 5799 N N   . ILE D 4 185 ? 121.309 106.801 70.907  1.00 71.49  ? 185 ILE R N   1 
ATOM 5800 C CA  . ILE D 4 185 ? 120.632 107.351 72.073  1.00 70.23  ? 185 ILE R CA  1 
ATOM 5801 C C   . ILE D 4 185 ? 119.384 106.543 72.383  1.00 73.50  ? 185 ILE R C   1 
ATOM 5802 O O   . ILE D 4 185 ? 119.095 106.248 73.544  1.00 79.94  ? 185 ILE R O   1 
ATOM 5803 C CB  . ILE D 4 185 ? 120.308 108.837 71.855  1.00 75.03  ? 185 ILE R CB  1 
ATOM 5804 C CG1 . ILE D 4 185 ? 121.591 109.624 71.595  1.00 80.17  ? 185 ILE R CG1 1 
ATOM 5805 C CG2 . ILE D 4 185 ? 119.584 109.398 73.061  1.00 76.90  ? 185 ILE R CG2 1 
ATOM 5806 C CD1 . ILE D 4 185 ? 122.579 109.577 72.739  1.00 78.52  ? 185 ILE R CD1 1 
ATOM 5807 N N   . ASN D 4 186 ? 118.640 106.152 71.349  1.00 74.80  ? 186 ASN R N   1 
ATOM 5808 C CA  . ASN D 4 186 ? 117.441 105.347 71.557  1.00 75.76  ? 186 ASN R CA  1 
ATOM 5809 C C   . ASN D 4 186 ? 117.777 104.004 72.195  1.00 84.01  ? 186 ASN R C   1 
ATOM 5810 O O   . ASN D 4 186 ? 117.108 103.569 73.140  1.00 86.08  ? 186 ASN R O   1 
ATOM 5811 C CB  . ASN D 4 186 ? 116.719 105.141 70.228  1.00 79.34  ? 186 ASN R CB  1 
ATOM 5812 C CG  . ASN D 4 186 ? 115.884 106.330 69.833  1.00 81.21  ? 186 ASN R CG  1 
ATOM 5813 O OD1 . ASN D 4 186 ? 115.799 107.313 70.566  1.00 82.31  ? 186 ASN R OD1 1 
ATOM 5814 N ND2 . ASN D 4 186 ? 115.254 106.249 68.670  1.00 79.97  ? 186 ASN R ND2 1 
ATOM 5815 N N   . TYR D 4 187 ? 118.813 103.330 71.688  1.00 84.12  ? 187 TYR R N   1 
ATOM 5816 C CA  . TYR D 4 187 ? 119.181 102.024 72.235  1.00 74.32  ? 187 TYR R CA  1 
ATOM 5817 C C   . TYR D 4 187 ? 119.621 102.136 73.690  1.00 74.74  ? 187 TYR R C   1 
ATOM 5818 O O   . TYR D 4 187 ? 119.142 101.391 74.560  1.00 79.37  ? 187 TYR R O   1 
ATOM 5819 C CB  . TYR D 4 187 ? 120.292 101.395 71.399  1.00 72.56  ? 187 TYR R CB  1 
ATOM 5820 C CG  . TYR D 4 187 ? 119.841 100.843 70.073  1.00 75.45  ? 187 TYR R CG  1 
ATOM 5821 C CD1 . TYR D 4 187 ? 118.737 100.015 69.986  1.00 78.68  ? 187 TYR R CD1 1 
ATOM 5822 C CD2 . TYR D 4 187 ? 120.524 101.149 68.908  1.00 80.17  ? 187 TYR R CD2 1 
ATOM 5823 C CE1 . TYR D 4 187 ? 118.322 99.507  68.774  1.00 82.94  ? 187 TYR R CE1 1 
ATOM 5824 C CE2 . TYR D 4 187 ? 120.120 100.648 67.693  1.00 83.82  ? 187 TYR R CE2 1 
ATOM 5825 C CZ  . TYR D 4 187 ? 119.018 99.827  67.630  1.00 86.81  ? 187 TYR R CZ  1 
ATOM 5826 O OH  . TYR D 4 187 ? 118.613 99.324  66.416  1.00 83.70  ? 187 TYR R OH  1 
ATOM 5827 N N   . TYR D 4 188 ? 120.553 103.053 73.970  1.00 63.49  ? 188 TYR R N   1 
ATOM 5828 C CA  . TYR D 4 188 ? 121.043 103.207 75.334  1.00 64.25  ? 188 TYR R CA  1 
ATOM 5829 C C   . TYR D 4 188 ? 119.920 103.630 76.264  1.00 64.77  ? 188 TYR R C   1 
ATOM 5830 O O   . TYR D 4 188 ? 119.854 103.188 77.418  1.00 71.82  ? 188 TYR R O   1 
ATOM 5831 C CB  . TYR D 4 188 ? 122.185 104.220 75.379  1.00 60.96  ? 188 TYR R CB  1 
ATOM 5832 N N   . ARG D 4 189 ? 119.013 104.471 75.768  1.00 65.34  ? 189 ARG R N   1 
ATOM 5833 C CA  . ARG D 4 189 ? 117.874 104.898 76.561  1.00 68.59  ? 189 ARG R CA  1 
ATOM 5834 C C   . ARG D 4 189 ? 116.998 103.712 76.919  1.00 69.41  ? 189 ARG R C   1 
ATOM 5835 O O   . ARG D 4 189 ? 116.666 103.508 78.091  1.00 76.98  ? 189 ARG R O   1 
ATOM 5836 C CB  . ARG D 4 189 ? 117.080 105.946 75.786  1.00 71.12  ? 189 ARG R CB  1 
ATOM 5837 C CG  . ARG D 4 189 ? 115.914 106.516 76.531  1.00 68.33  ? 189 ARG R CG  1 
ATOM 5838 C CD  . ARG D 4 189 ? 115.236 107.592 75.711  1.00 70.02  ? 189 ARG R CD  1 
ATOM 5839 N NE  . ARG D 4 189 ? 116.070 108.773 75.546  1.00 72.60  ? 189 ARG R NE  1 
ATOM 5840 C CZ  . ARG D 4 189 ? 115.776 109.781 74.733  1.00 74.21  ? 189 ARG R CZ  1 
ATOM 5841 N NH1 . ARG D 4 189 ? 114.670 109.746 74.007  1.00 72.82  ? 189 ARG R NH1 1 
ATOM 5842 N NH2 . ARG D 4 189 ? 116.591 110.822 74.642  1.00 71.88  ? 189 ARG R NH2 1 
ATOM 5843 N N   . PHE D 4 190 ? 116.649 102.889 75.927  1.00 64.11  ? 190 PHE R N   1 
ATOM 5844 C CA  . PHE D 4 190 ? 115.832 101.717 76.211  1.00 65.84  ? 190 PHE R CA  1 
ATOM 5845 C C   . PHE D 4 190 ? 116.478 100.843 77.270  1.00 68.14  ? 190 PHE R C   1 
ATOM 5846 O O   . PHE D 4 190 ? 115.871 100.569 78.311  1.00 70.79  ? 190 PHE R O   1 
ATOM 5847 C CB  . PHE D 4 190 ? 115.586 100.900 74.946  1.00 70.38  ? 190 PHE R CB  1 
ATOM 5848 C CG  . PHE D 4 190 ? 114.721 99.697  75.179  1.00 69.30  ? 190 PHE R CG  1 
ATOM 5849 C CD1 . PHE D 4 190 ? 113.358 99.830  75.346  1.00 70.34  ? 190 PHE R CD1 1 
ATOM 5850 C CD2 . PHE D 4 190 ? 115.276 98.437  75.257  1.00 68.10  ? 190 PHE R CD2 1 
ATOM 5851 C CE1 . PHE D 4 190 ? 112.565 98.724  75.575  1.00 69.10  ? 190 PHE R CE1 1 
ATOM 5852 C CE2 . PHE D 4 190 ? 114.492 97.333  75.483  1.00 69.75  ? 190 PHE R CE2 1 
ATOM 5853 C CZ  . PHE D 4 190 ? 113.136 97.475  75.646  1.00 70.58  ? 190 PHE R CZ  1 
ATOM 5854 N N   . LEU D 4 191 ? 117.731 100.442 77.050  1.00 63.72  ? 191 LEU R N   1 
ATOM 5855 C CA  . LEU D 4 191 ? 118.379 99.548  78.008  1.00 58.19  ? 191 LEU R CA  1 
ATOM 5856 C C   . LEU D 4 191 ? 118.413 100.167 79.400  1.00 58.27  ? 191 LEU R C   1 
ATOM 5857 O O   . LEU D 4 191 ? 117.762 99.670  80.326  1.00 66.33  ? 191 LEU R O   1 
ATOM 5858 C CB  . LEU D 4 191 ? 119.786 99.178  77.540  1.00 62.23  ? 191 LEU R CB  1 
ATOM 5859 C CG  . LEU D 4 191 ? 119.936 98.032  76.533  1.00 64.00  ? 191 LEU R CG  1 
ATOM 5860 C CD1 . LEU D 4 191 ? 119.465 96.725  77.155  1.00 65.11  ? 191 LEU R CD1 1 
ATOM 5861 C CD2 . LEU D 4 191 ? 119.209 98.290  75.219  1.00 64.57  ? 191 LEU R CD2 1 
ATOM 5862 N N   . VAL D 4 192 ? 119.116 101.292 79.551  1.00 56.67  ? 192 VAL R N   1 
ATOM 5863 C CA  . VAL D 4 192 ? 119.372 101.838 80.880  1.00 56.14  ? 192 VAL R CA  1 
ATOM 5864 C C   . VAL D 4 192 ? 118.074 102.225 81.581  1.00 64.17  ? 192 VAL R C   1 
ATOM 5865 O O   . VAL D 4 192 ? 117.907 101.967 82.778  1.00 63.32  ? 192 VAL R O   1 
ATOM 5866 C CB  . VAL D 4 192 ? 120.341 103.029 80.793  1.00 63.23  ? 192 VAL R CB  1 
ATOM 5867 C CG1 . VAL D 4 192 ? 120.525 103.662 82.159  1.00 66.48  ? 192 VAL R CG1 1 
ATOM 5868 C CG2 . VAL D 4 192 ? 121.677 102.580 80.227  1.00 63.38  ? 192 VAL R CG2 1 
ATOM 5869 N N   . GLY D 4 193 ? 117.137 102.855 80.865  1.00 67.99  ? 193 GLY R N   1 
ATOM 5870 C CA  . GLY D 4 193 ? 115.934 103.347 81.501  1.00 64.99  ? 193 GLY R CA  1 
ATOM 5871 C C   . GLY D 4 193 ? 114.759 102.403 81.591  1.00 65.85  ? 193 GLY R C   1 
ATOM 5872 O O   . GLY D 4 193 ? 113.791 102.732 82.279  1.00 70.19  ? 193 GLY R O   1 
ATOM 5873 N N   . PHE D 4 194 ? 114.784 101.237 80.929  1.00 65.89  ? 194 PHE R N   1 
ATOM 5874 C CA  . PHE D 4 194 ? 113.656 100.325 81.073  1.00 69.88  ? 194 PHE R CA  1 
ATOM 5875 C C   . PHE D 4 194 ? 114.058 98.854  81.149  1.00 71.80  ? 194 PHE R C   1 
ATOM 5876 O O   . PHE D 4 194 ? 113.214 97.983  80.909  1.00 73.01  ? 194 PHE R O   1 
ATOM 5877 C CB  . PHE D 4 194 ? 112.657 100.504 79.933  1.00 68.36  ? 194 PHE R CB  1 
ATOM 5878 C CG  . PHE D 4 194 ? 111.283 100.006 80.259  1.00 68.06  ? 194 PHE R CG  1 
ATOM 5879 C CD1 . PHE D 4 194 ? 110.560 100.560 81.295  1.00 70.69  ? 194 PHE R CD1 1 
ATOM 5880 C CD2 . PHE D 4 194 ? 110.726 98.963  79.542  1.00 68.81  ? 194 PHE R CD2 1 
ATOM 5881 C CE1 . PHE D 4 194 ? 109.300 100.096 81.600  1.00 72.89  ? 194 PHE R CE1 1 
ATOM 5882 C CE2 . PHE D 4 194 ? 109.471 98.493  79.842  1.00 71.95  ? 194 PHE R CE2 1 
ATOM 5883 C CZ  . PHE D 4 194 ? 108.755 99.060  80.872  1.00 72.11  ? 194 PHE R CZ  1 
ATOM 5884 N N   . LEU D 4 195 ? 115.304 98.530  81.475  1.00 65.18  ? 195 LEU R N   1 
ATOM 5885 C CA  . LEU D 4 195 ? 115.581 97.127  81.733  1.00 62.96  ? 195 LEU R CA  1 
ATOM 5886 C C   . LEU D 4 195 ? 116.243 97.009  83.095  1.00 63.93  ? 195 LEU R C   1 
ATOM 5887 O O   . LEU D 4 195 ? 116.091 95.997  83.786  1.00 69.44  ? 195 LEU R O   1 
ATOM 5888 C CB  . LEU D 4 195 ? 116.450 96.534  80.626  1.00 62.86  ? 195 LEU R CB  1 
ATOM 5889 C CG  . LEU D 4 195 ? 116.759 95.042  80.726  1.00 61.75  ? 195 LEU R CG  1 
ATOM 5890 C CD1 . LEU D 4 195 ? 115.472 94.243  80.634  1.00 61.25  ? 195 LEU R CD1 1 
ATOM 5891 C CD2 . LEU D 4 195 ? 117.739 94.616  79.646  1.00 63.98  ? 195 LEU R CD2 1 
ATOM 5892 N N   . PHE D 4 196 ? 116.974 98.042  83.489  1.00 59.59  ? 196 PHE R N   1 
ATOM 5893 C CA  . PHE D 4 196 ? 117.550 98.111  84.823  1.00 61.18  ? 196 PHE R CA  1 
ATOM 5894 C C   . PHE D 4 196 ? 116.499 98.521  85.855  1.00 66.52  ? 196 PHE R C   1 
ATOM 5895 O O   . PHE D 4 196 ? 116.341 97.822  86.869  1.00 75.82  ? 196 PHE R O   1 
ATOM 5896 C CB  . PHE D 4 196 ? 118.743 99.068  84.838  1.00 60.85  ? 196 PHE R CB  1 
ATOM 5897 C CG  . PHE D 4 196 ? 119.752 98.763  85.902  1.00 64.94  ? 196 PHE R CG  1 
ATOM 5898 C CD1 . PHE D 4 196 ? 120.714 97.790  85.705  1.00 68.91  ? 196 PHE R CD1 1 
ATOM 5899 C CD2 . PHE D 4 196 ? 119.744 99.456  87.098  1.00 69.22  ? 196 PHE R CD2 1 
ATOM 5900 C CE1 . PHE D 4 196 ? 121.646 97.510  86.685  1.00 70.92  ? 196 PHE R CE1 1 
ATOM 5901 C CE2 . PHE D 4 196 ? 120.668 99.182  88.080  1.00 69.38  ? 196 PHE R CE2 1 
ATOM 5902 C CZ  . PHE D 4 196 ? 121.622 98.208  87.875  1.00 69.01  ? 196 PHE R CZ  1 
ATOM 5903 N N   . PRO D 4 197 ? 115.765 99.628  85.659  1.00 51.32  ? 197 PRO R N   1 
ATOM 5904 C CA  . PRO D 4 197 ? 114.785 100.016 86.684  1.00 56.66  ? 197 PRO R CA  1 
ATOM 5905 C C   . PRO D 4 197 ? 113.685 98.995  86.894  1.00 62.35  ? 197 PRO R C   1 
ATOM 5906 O O   . PRO D 4 197 ? 113.254 98.793  88.034  1.00 67.90  ? 197 PRO R O   1 
ATOM 5907 C CB  . PRO D 4 197 ? 114.234 101.346 86.155  1.00 61.24  ? 197 PRO R CB  1 
ATOM 5908 C CG  . PRO D 4 197 ? 115.257 101.835 85.220  1.00 64.18  ? 197 PRO R CG  1 
ATOM 5909 C CD  . PRO D 4 197 ? 115.774 100.607 84.562  1.00 61.74  ? 197 PRO R CD  1 
ATOM 5910 N N   . ILE D 4 198 ? 113.220 98.334  85.834  1.00 64.83  ? 198 ILE R N   1 
ATOM 5911 C CA  . ILE D 4 198 ? 112.132 97.377  86.005  1.00 64.33  ? 198 ILE R CA  1 
ATOM 5912 C C   . ILE D 4 198 ? 112.621 96.140  86.746  1.00 67.84  ? 198 ILE R C   1 
ATOM 5913 O O   . ILE D 4 198 ? 111.917 95.601  87.611  1.00 70.37  ? 198 ILE R O   1 
ATOM 5914 C CB  . ILE D 4 198 ? 111.494 97.024  84.650  1.00 61.47  ? 198 ILE R CB  1 
ATOM 5915 C CG1 . ILE D 4 198 ? 110.309 96.084  84.857  1.00 63.76  ? 198 ILE R CG1 1 
ATOM 5916 C CG2 . ILE D 4 198 ? 112.514 96.418  83.697  1.00 62.54  ? 198 ILE R CG2 1 
ATOM 5917 C CD1 . ILE D 4 198 ? 109.558 95.766  83.588  1.00 65.66  ? 198 ILE R CD1 1 
ATOM 5918 N N   . CYS D 4 199 ? 113.831 95.672  86.430  1.00 60.83  ? 199 CYS R N   1 
ATOM 5919 C CA  . CYS D 4 199 ? 114.391 94.544  87.164  1.00 52.88  ? 199 CYS R CA  1 
ATOM 5920 C C   . CYS D 4 199 ? 114.586 94.896  88.627  1.00 53.83  ? 199 CYS R C   1 
ATOM 5921 O O   . CYS D 4 199 ? 114.289 94.085  89.512  1.00 60.56  ? 199 CYS R O   1 
ATOM 5922 C CB  . CYS D 4 199 ? 115.709 94.100  86.537  1.00 55.34  ? 199 CYS R CB  1 
ATOM 5923 S SG  . CYS D 4 199 ? 115.528 93.168  85.007  1.00 70.95  ? 199 CYS R SG  1 
ATOM 5924 N N   . LEU D 4 200 ? 115.066 96.107  88.904  1.00 44.02  ? 200 LEU R N   1 
ATOM 5925 C CA  . LEU D 4 200 ? 115.248 96.518  90.289  1.00 48.29  ? 200 LEU R CA  1 
ATOM 5926 C C   . LEU D 4 200 ? 113.913 96.586  91.023  1.00 56.45  ? 200 LEU R C   1 
ATOM 5927 O O   . LEU D 4 200 ? 113.793 96.100  92.156  1.00 63.82  ? 200 LEU R O   1 
ATOM 5928 C CB  . LEU D 4 200 ? 115.980 97.858  90.332  1.00 48.71  ? 200 LEU R CB  1 
ATOM 5929 C CG  . LEU D 4 200 ? 116.455 98.435  91.661  1.00 53.99  ? 200 LEU R CG  1 
ATOM 5930 C CD1 . LEU D 4 200 ? 117.646 99.328  91.401  1.00 52.55  ? 200 LEU R CD1 1 
ATOM 5931 C CD2 . LEU D 4 200 ? 115.358 99.225  92.354  1.00 59.15  ? 200 LEU R CD2 1 
ATOM 5932 N N   . LEU D 4 201 ? 112.891 97.161  90.385  1.00 53.28  ? 201 LEU R N   1 
ATOM 5933 C CA  . LEU D 4 201 ? 111.575 97.257  91.010  1.00 50.34  ? 201 LEU R CA  1 
ATOM 5934 C C   . LEU D 4 201 ? 111.009 95.878  91.317  1.00 58.71  ? 201 LEU R C   1 
ATOM 5935 O O   . LEU D 4 201 ? 110.521 95.625  92.426  1.00 67.30  ? 201 LEU R O   1 
ATOM 5936 C CB  . LEU D 4 201 ? 110.618 98.024  90.102  1.00 47.85  ? 201 LEU R CB  1 
ATOM 5937 C CG  . LEU D 4 201 ? 110.549 99.543  90.192  1.00 54.81  ? 201 LEU R CG  1 
ATOM 5938 C CD1 . LEU D 4 201 ? 109.500 100.063 89.237  1.00 58.13  ? 201 LEU R CD1 1 
ATOM 5939 C CD2 . LEU D 4 201 ? 110.231 99.975  91.602  1.00 55.15  ? 201 LEU R CD2 1 
ATOM 5940 N N   . LEU D 4 202 ? 111.065 94.970  90.341  1.00 47.51  ? 202 LEU R N   1 
ATOM 5941 C CA  . LEU D 4 202 ? 110.520 93.635  90.551  1.00 45.95  ? 202 LEU R CA  1 
ATOM 5942 C C   . LEU D 4 202 ? 111.286 92.884  91.633  1.00 57.83  ? 202 LEU R C   1 
ATOM 5943 O O   . LEU D 4 202 ? 110.679 92.250  92.507  1.00 67.56  ? 202 LEU R O   1 
ATOM 5944 C CB  . LEU D 4 202 ? 110.534 92.855  89.240  1.00 47.47  ? 202 LEU R CB  1 
ATOM 5945 C CG  . LEU D 4 202 ? 109.423 93.206  88.255  1.00 56.32  ? 202 LEU R CG  1 
ATOM 5946 C CD1 . LEU D 4 202 ? 109.339 92.163  87.160  1.00 59.70  ? 202 LEU R CD1 1 
ATOM 5947 C CD2 . LEU D 4 202 ? 108.102 93.332  88.977  1.00 54.87  ? 202 LEU R CD2 1 
ATOM 5948 N N   . ALA D 4 203 ? 112.620 92.950  91.600  1.00 50.69  ? 203 ALA R N   1 
ATOM 5949 C CA  . ALA D 4 203 ? 113.428 92.221  92.566  1.00 49.74  ? 203 ALA R CA  1 
ATOM 5950 C C   . ALA D 4 203 ? 113.347 92.814  93.962  1.00 50.79  ? 203 ALA R C   1 
ATOM 5951 O O   . ALA D 4 203 ? 113.688 92.127  94.929  1.00 54.25  ? 203 ALA R O   1 
ATOM 5952 C CB  . ALA D 4 203 ? 114.884 92.176  92.109  1.00 50.61  ? 203 ALA R CB  1 
ATOM 5953 N N   . SER D 4 204 ? 112.917 94.065  94.097  1.00 37.93  ? 204 SER R N   1 
ATOM 5954 C CA  . SER D 4 204 ? 112.682 94.594  95.433  1.00 38.84  ? 204 SER R CA  1 
ATOM 5955 C C   . SER D 4 204 ? 111.281 94.274  95.935  1.00 45.15  ? 204 SER R C   1 
ATOM 5956 O O   . SER D 4 204 ? 111.098 93.932  97.114  1.00 56.26  ? 204 SER R O   1 
ATOM 5957 C CB  . SER D 4 204 ? 112.906 96.104  95.447  1.00 41.42  ? 204 SER R CB  1 
ATOM 5958 O OG  . SER D 4 204 ? 111.941 96.765  94.652  1.00 48.73  ? 204 SER R OG  1 
ATOM 5959 N N   . TYR D 4 205 ? 110.285 94.344  95.055  1.00 38.08  ? 205 TYR R N   1 
ATOM 5960 C CA  . TYR D 4 205 ? 108.918 94.152  95.509  1.00 35.50  ? 205 TYR R CA  1 
ATOM 5961 C C   . TYR D 4 205 ? 108.603 92.684  95.762  1.00 42.78  ? 205 TYR R C   1 
ATOM 5962 O O   . TYR D 4 205 ? 107.802 92.376  96.653  1.00 52.67  ? 205 TYR R O   1 
ATOM 5963 C CB  . TYR D 4 205 ? 107.956 94.772  94.504  1.00 39.38  ? 205 TYR R CB  1 
ATOM 5964 C CG  . TYR D 4 205 ? 107.796 96.256  94.729  1.00 40.20  ? 205 TYR R CG  1 
ATOM 5965 C CD1 . TYR D 4 205 ? 107.395 96.747  95.954  1.00 40.55  ? 205 TYR R CD1 1 
ATOM 5966 C CD2 . TYR D 4 205 ? 108.080 97.164  93.729  1.00 45.22  ? 205 TYR R CD2 1 
ATOM 5967 C CE1 . TYR D 4 205 ? 107.264 98.097  96.170  1.00 38.50  ? 205 TYR R CE1 1 
ATOM 5968 C CE2 . TYR D 4 205 ? 107.951 98.514  93.939  1.00 43.18  ? 205 TYR R CE2 1 
ATOM 5969 C CZ  . TYR D 4 205 ? 107.543 98.973  95.160  1.00 34.24  ? 205 TYR R CZ  1 
ATOM 5970 O OH  . TYR D 4 205 ? 107.412 100.321 95.370  1.00 41.60  ? 205 TYR R OH  1 
ATOM 5971 N N   . GLN D 4 206 ? 109.237 91.766  95.029  1.00 47.31  ? 206 GLN R N   1 
ATOM 5972 C CA  . GLN D 4 206 ? 109.110 90.354  95.373  1.00 41.42  ? 206 GLN R CA  1 
ATOM 5973 C C   . GLN D 4 206 ? 109.659 90.080  96.765  1.00 54.11  ? 206 GLN R C   1 
ATOM 5974 O O   . GLN D 4 206 ? 109.053 89.333  97.547  1.00 63.39  ? 206 GLN R O   1 
ATOM 5975 C CB  . GLN D 4 206 ? 109.827 89.492  94.340  1.00 44.22  ? 206 GLN R CB  1 
ATOM 5976 C CG  . GLN D 4 206 ? 109.689 88.006  94.580  1.00 51.94  ? 206 GLN R CG  1 
ATOM 5977 C CD  . GLN D 4 206 ? 108.255 87.536  94.509  1.00 58.50  ? 206 GLN R CD  1 
ATOM 5978 O OE1 . GLN D 4 206 ? 107.629 87.259  95.532  1.00 54.95  ? 206 GLN R OE1 1 
ATOM 5979 N NE2 . GLN D 4 206 ? 107.722 87.443  93.296  1.00 57.53  ? 206 GLN R NE2 1 
ATOM 5980 N N   . GLY D 4 207 ? 110.803 90.679  97.096  1.00 44.80  ? 207 GLY R N   1 
ATOM 5981 C CA  . GLY D 4 207 ? 111.349 90.518  98.431  1.00 42.67  ? 207 GLY R CA  1 
ATOM 5982 C C   . GLY D 4 207 ? 110.433 91.070  99.503  1.00 53.14  ? 207 GLY R C   1 
ATOM 5983 O O   . GLY D 4 207 ? 110.233 90.442  100.548 1.00 66.02  ? 207 GLY R O   1 
ATOM 5984 N N   . ILE D 4 208 ? 109.854 92.247  99.257  1.00 38.24  ? 208 ILE R N   1 
ATOM 5985 C CA  . ILE D 4 208 ? 108.941 92.826  100.240 1.00 34.24  ? 208 ILE R CA  1 
ATOM 5986 C C   . ILE D 4 208 ? 107.724 91.930  100.439 1.00 41.12  ? 208 ILE R C   1 
ATOM 5987 O O   . ILE D 4 208 ? 107.279 91.707  101.573 1.00 48.96  ? 208 ILE R O   1 
ATOM 5988 C CB  . ILE D 4 208 ? 108.530 94.250  99.833  1.00 35.39  ? 208 ILE R CB  1 
ATOM 5989 C CG1 . ILE D 4 208 ? 109.744 95.168  99.799  1.00 42.71  ? 208 ILE R CG1 1 
ATOM 5990 C CG2 . ILE D 4 208 ? 107.536 94.803  100.812 1.00 39.18  ? 208 ILE R CG2 1 
ATOM 5991 C CD1 . ILE D 4 208 ? 109.466 96.506  99.165  1.00 46.52  ? 208 ILE R CD1 1 
ATOM 5992 N N   . LEU D 4 209 ? 107.163 91.402  99.348  1.00 35.21  ? 209 LEU R N   1 
ATOM 5993 C CA  . LEU D 4 209 ? 105.989 90.542  99.473  1.00 37.22  ? 209 LEU R CA  1 
ATOM 5994 C C   . LEU D 4 209 ? 106.314 89.249  100.209 1.00 42.08  ? 209 LEU R C   1 
ATOM 5995 O O   . LEU D 4 209 ? 105.515 88.780  101.030 1.00 53.33  ? 209 LEU R O   1 
ATOM 5996 C CB  . LEU D 4 209 ? 105.398 90.239  98.100  1.00 45.14  ? 209 LEU R CB  1 
ATOM 5997 C CG  . LEU D 4 209 ? 104.541 91.335  97.473  1.00 41.59  ? 209 LEU R CG  1 
ATOM 5998 C CD1 . LEU D 4 209 ? 104.024 90.897  96.121  1.00 43.59  ? 209 LEU R CD1 1 
ATOM 5999 C CD2 . LEU D 4 209 ? 103.393 91.680  98.390  1.00 44.62  ? 209 LEU R CD2 1 
ATOM 6000 N N   . ARG D 4 210 ? 107.473 88.652  99.935  1.00 39.41  ? 210 ARG R N   1 
ATOM 6001 C CA  . ARG D 4 210 ? 107.856 87.447  100.663 1.00 47.19  ? 210 ARG R CA  1 
ATOM 6002 C C   . ARG D 4 210 ? 108.021 87.734  102.152 1.00 49.05  ? 210 ARG R C   1 
ATOM 6003 O O   . ARG D 4 210 ? 107.540 86.969  103.002 1.00 55.19  ? 210 ARG R O   1 
ATOM 6004 C CB  . ARG D 4 210 ? 109.139 86.872  100.071 1.00 53.91  ? 210 ARG R CB  1 
ATOM 6005 C CG  . ARG D 4 210 ? 109.783 85.783  100.899 1.00 57.02  ? 210 ARG R CG  1 
ATOM 6006 C CD  . ARG D 4 210 ? 110.994 85.210  100.188 1.00 57.96  ? 210 ARG R CD  1 
ATOM 6007 N NE  . ARG D 4 210 ? 110.865 85.297  98.737  1.00 60.86  ? 210 ARG R NE  1 
ATOM 6008 C CZ  . ARG D 4 210 ? 110.289 84.368  97.980  1.00 61.54  ? 210 ARG R CZ  1 
ATOM 6009 N NH1 . ARG D 4 210 ? 109.784 83.276  98.536  1.00 59.17  ? 210 ARG R NH1 1 
ATOM 6010 N NH2 . ARG D 4 210 ? 110.216 84.532  96.666  1.00 57.99  ? 210 ARG R NH2 1 
ATOM 6011 N N   . ALA D 4 211 ? 108.671 88.850  102.486 1.00 36.63  ? 211 ALA R N   1 
ATOM 6012 C CA  . ALA D 4 211 ? 108.860 89.198  103.889 1.00 36.56  ? 211 ALA R CA  1 
ATOM 6013 C C   . ALA D 4 211 ? 107.528 89.435  104.586 1.00 43.68  ? 211 ALA R C   1 
ATOM 6014 O O   . ALA D 4 211 ? 107.350 89.035  105.742 1.00 48.82  ? 211 ALA R O   1 
ATOM 6015 C CB  . ALA D 4 211 ? 109.753 90.429  104.010 1.00 36.57  ? 211 ALA R CB  1 
ATOM 6016 N N   . VAL D 4 212 ? 106.580 90.083  103.910 1.00 46.66  ? 212 VAL R N   1 
ATOM 6017 C CA  . VAL D 4 212 ? 105.310 90.361  104.573 1.00 43.16  ? 212 VAL R CA  1 
ATOM 6018 C C   . VAL D 4 212 ? 104.443 89.107  104.662 1.00 47.46  ? 212 VAL R C   1 
ATOM 6019 O O   . VAL D 4 212 ? 103.638 88.976  105.589 1.00 54.90  ? 212 VAL R O   1 
ATOM 6020 C CB  . VAL D 4 212 ? 104.565 91.518  103.882 1.00 45.58  ? 212 VAL R CB  1 
ATOM 6021 C CG1 . VAL D 4 212 ? 104.148 91.143  102.483 1.00 47.22  ? 212 VAL R CG1 1 
ATOM 6022 C CG2 . VAL D 4 212 ? 103.368 91.954  104.701 1.00 45.56  ? 212 VAL R CG2 1 
ATOM 6023 N N   . ARG D 4 213 ? 104.587 88.157  103.735 1.00 46.99  ? 213 ARG R N   1 
ATOM 6024 C CA  . ARG D 4 213 ? 103.799 86.936  103.854 1.00 43.87  ? 213 ARG R CA  1 
ATOM 6025 C C   . ARG D 4 213 ? 104.405 85.940  104.828 1.00 48.80  ? 213 ARG R C   1 
ATOM 6026 O O   . ARG D 4 213 ? 103.710 85.011  105.247 1.00 51.79  ? 213 ARG R O   1 
ATOM 6027 C CB  . ARG D 4 213 ? 103.619 86.251  102.497 1.00 51.76  ? 213 ARG R CB  1 
ATOM 6028 C CG  . ARG D 4 213 ? 104.889 85.666  101.909 1.00 56.47  ? 213 ARG R CG  1 
ATOM 6029 C CD  . ARG D 4 213 ? 104.638 84.999  100.562 1.00 57.37  ? 213 ARG R CD  1 
ATOM 6030 N NE  . ARG D 4 213 ? 104.217 85.945  99.534  1.00 60.37  ? 213 ARG R NE  1 
ATOM 6031 C CZ  . ARG D 4 213 ? 102.985 86.011  99.041  1.00 61.57  ? 213 ARG R CZ  1 
ATOM 6032 N NH1 . ARG D 4 213 ? 102.048 85.183  99.482  1.00 59.78  ? 213 ARG R NH1 1 
ATOM 6033 N NH2 . ARG D 4 213 ? 102.691 86.903  98.106  1.00 57.27  ? 213 ARG R NH2 1 
ATOM 6034 N N   . ARG D 4 214 ? 105.675 86.096  105.192 1.00 52.03  ? 214 ARG R N   1 
ATOM 6035 C CA  . ARG D 4 214 ? 106.259 85.254  106.230 1.00 49.12  ? 214 ARG R CA  1 
ATOM 6036 C C   . ARG D 4 214 ? 106.062 85.811  107.634 1.00 51.54  ? 214 ARG R C   1 
ATOM 6037 O O   . ARG D 4 214 ? 106.524 85.194  108.597 1.00 60.17  ? 214 ARG R O   1 
ATOM 6038 C CB  . ARG D 4 214 ? 107.755 85.047  105.972 1.00 45.77  ? 214 ARG R CB  1 
ATOM 6039 N N   . SER D 4 215 ? 105.390 86.950  107.775 1.00 55.62  ? 215 SER R N   1 
ATOM 6040 C CA  . SER D 4 215 ? 105.243 87.611  109.060 1.00 53.88  ? 215 SER R CA  1 
ATOM 6041 C C   . SER D 4 215 ? 104.178 86.922  109.908 1.00 57.83  ? 215 SER R C   1 
ATOM 6042 O O   . SER D 4 215 ? 103.496 85.993  109.470 1.00 61.12  ? 215 SER R O   1 
ATOM 6043 C CB  . SER D 4 215 ? 104.895 89.082  108.864 1.00 54.40  ? 215 SER R CB  1 
ATOM 6044 O OG  . SER D 4 215 ? 105.079 89.815  110.060 1.00 60.10  ? 215 SER R OG  1 
ATOM 6045 N N   . HIS D 4 216 ? 104.042 87.392  111.144 1.00 65.92  ? 216 HIS R N   1 
ATOM 6046 C CA  . HIS D 4 216 ? 103.104 86.825  112.104 1.00 59.61  ? 216 HIS R CA  1 
ATOM 6047 C C   . HIS D 4 216 ? 102.099 87.828  112.640 1.00 63.25  ? 216 HIS R C   1 
ATOM 6048 O O   . HIS D 4 216 ? 100.922 87.493  112.782 1.00 70.66  ? 216 HIS R O   1 
ATOM 6049 C CB  . HIS D 4 216 ? 103.861 86.214  113.288 1.00 59.44  ? 216 HIS R CB  1 
ATOM 6050 C CG  . HIS D 4 216 ? 104.431 84.860  113.012 1.00 67.76  ? 216 HIS R CG  1 
ATOM 6051 N ND1 . HIS D 4 216 ? 105.735 84.529  113.309 1.00 69.21  ? 216 HIS R ND1 1 
ATOM 6052 C CD2 . HIS D 4 216 ? 103.874 83.751  112.472 1.00 70.15  ? 216 HIS R CD2 1 
ATOM 6053 C CE1 . HIS D 4 216 ? 105.959 83.275  112.960 1.00 69.46  ? 216 HIS R CE1 1 
ATOM 6054 N NE2 . HIS D 4 216 ? 104.846 82.780  112.449 1.00 71.39  ? 216 HIS R NE2 1 
ATOM 6055 N N   . GLY D 4 217 ? 102.527 89.050  112.945 1.00 55.94  ? 217 GLY R N   1 
ATOM 6056 C CA  . GLY D 4 217 ? 101.663 89.998  113.620 1.00 55.55  ? 217 GLY R CA  1 
ATOM 6057 C C   . GLY D 4 217 ? 100.692 90.743  112.739 1.00 61.27  ? 217 GLY R C   1 
ATOM 6058 O O   . GLY D 4 217 ? 99.794  91.408  113.262 1.00 63.66  ? 217 GLY R O   1 
ATOM 6059 N N   . THR D 4 218 ? 100.841 90.654  111.423 1.00 54.30  ? 218 THR R N   1 
ATOM 6060 C CA  . THR D 4 218 ? 99.929  91.309  110.498 1.00 46.05  ? 218 THR R CA  1 
ATOM 6061 C C   . THR D 4 218 ? 98.713  90.424  110.279 1.00 52.52  ? 218 THR R C   1 
ATOM 6062 O O   . THR D 4 218 ? 98.851  89.232  109.990 1.00 57.60  ? 218 THR R O   1 
ATOM 6063 C CB  . THR D 4 218 ? 100.615 91.602  109.168 1.00 40.28  ? 218 THR R CB  1 
ATOM 6064 O OG1 . THR D 4 218 ? 101.736 92.463  109.390 1.00 45.14  ? 218 THR R OG1 1 
ATOM 6065 C CG2 . THR D 4 218 ? 99.651  92.285  108.225 1.00 48.84  ? 218 THR R CG2 1 
ATOM 6066 N N   . GLN D 4 219 ? 97.527  91.004  110.434 1.00 41.63  ? 219 GLN R N   1 
ATOM 6067 C CA  . GLN D 4 219 ? 96.309  90.241  110.243 1.00 40.88  ? 219 GLN R CA  1 
ATOM 6068 C C   . GLN D 4 219 ? 96.179  89.806  108.784 1.00 48.54  ? 219 GLN R C   1 
ATOM 6069 O O   . GLN D 4 219 ? 96.882  90.291  107.894 1.00 59.26  ? 219 GLN R O   1 
ATOM 6070 C CB  . GLN D 4 219 ? 95.094  91.060  110.667 1.00 46.81  ? 219 GLN R CB  1 
ATOM 6071 N N   . LYS D 4 220 ? 95.260  88.867  108.549 1.00 43.54  ? 220 LYS R N   1 
ATOM 6072 C CA  . LYS D 4 220 ? 95.029  88.367  107.196 1.00 46.73  ? 220 LYS R CA  1 
ATOM 6073 C C   . LYS D 4 220 ? 94.668  89.495  106.240 1.00 55.21  ? 220 LYS R C   1 
ATOM 6074 O O   . LYS D 4 220 ? 95.041  89.464  105.062 1.00 61.58  ? 220 LYS R O   1 
ATOM 6075 C CB  . LYS D 4 220 ? 93.921  87.313  107.206 1.00 30.00  ? 220 LYS R CB  1 
ATOM 6076 N N   . SER D 4 221 ? 93.941  90.498  106.730 1.00 47.03  ? 221 SER R N   1 
ATOM 6077 C CA  . SER D 4 221 ? 93.418  91.537  105.852 1.00 44.35  ? 221 SER R CA  1 
ATOM 6078 C C   . SER D 4 221 ? 94.531  92.397  105.264 1.00 47.16  ? 221 SER R C   1 
ATOM 6079 O O   . SER D 4 221 ? 94.525  92.699  104.066 1.00 59.04  ? 221 SER R O   1 
ATOM 6080 C CB  . SER D 4 221 ? 92.419  92.403  106.616 1.00 30.00  ? 221 SER R CB  1 
ATOM 6081 O OG  . SER D 4 221 ? 91.930  93.450  105.802 1.00 30.00  ? 221 SER R OG  1 
ATOM 6082 N N   . ARG D 4 222 ? 95.488  92.817  106.092 1.00 38.98  ? 222 ARG R N   1 
ATOM 6083 C CA  . ARG D 4 222 ? 96.430  93.836  105.641 1.00 40.97  ? 222 ARG R CA  1 
ATOM 6084 C C   . ARG D 4 222 ? 97.449  93.290  104.650 1.00 47.92  ? 222 ARG R C   1 
ATOM 6085 O O   . ARG D 4 222 ? 97.979  94.049  103.831 1.00 59.83  ? 222 ARG R O   1 
ATOM 6086 C CB  . ARG D 4 222 ? 97.119  94.505  106.824 1.00 41.74  ? 222 ARG R CB  1 
ATOM 6087 C CG  . ARG D 4 222 ? 96.166  95.332  107.658 1.00 46.72  ? 222 ARG R CG  1 
ATOM 6088 C CD  . ARG D 4 222 ? 96.861  96.025  108.807 1.00 51.77  ? 222 ARG R CD  1 
ATOM 6089 N NE  . ARG D 4 222 ? 95.902  96.738  109.641 1.00 53.18  ? 222 ARG R NE  1 
ATOM 6090 C CZ  . ARG D 4 222 ? 95.520  97.993  109.440 1.00 52.28  ? 222 ARG R CZ  1 
ATOM 6091 N NH1 . ARG D 4 222 ? 96.024  98.692  108.432 1.00 48.67  ? 222 ARG R NH1 1 
ATOM 6092 N NH2 . ARG D 4 222 ? 94.638  98.554  110.253 1.00 52.62  ? 222 ARG R NH2 1 
ATOM 6093 N N   . LYS D 4 223 ? 97.764  91.997  104.709 1.00 40.75  ? 223 LYS R N   1 
ATOM 6094 C CA  . LYS D 4 223 ? 98.673  91.455  103.705 1.00 41.08  ? 223 LYS R CA  1 
ATOM 6095 C C   . LYS D 4 223 ? 98.041  91.467  102.319 1.00 52.70  ? 223 LYS R C   1 
ATOM 6096 O O   . LYS D 4 223 ? 98.729  91.698  101.316 1.00 58.26  ? 223 LYS R O   1 
ATOM 6097 C CB  . LYS D 4 223 ? 99.142  90.053  104.081 1.00 46.07  ? 223 LYS R CB  1 
ATOM 6098 C CG  . LYS D 4 223 ? 99.247  89.782  105.563 1.00 56.96  ? 223 LYS R CG  1 
ATOM 6099 C CD  . LYS D 4 223 ? 99.902  88.427  105.795 1.00 50.54  ? 223 LYS R CD  1 
ATOM 6100 C CE  . LYS D 4 223 ? 99.818  87.995  107.240 1.00 51.07  ? 223 LYS R CE  1 
ATOM 6101 N NZ  . LYS D 4 223 ? 99.744  86.521  107.383 1.00 47.31  ? 223 LYS R NZ  1 
ATOM 6102 N N   . ASP D 4 224 ? 96.734  91.222  102.237 1.00 52.91  ? 224 ASP R N   1 
ATOM 6103 C CA  . ASP D 4 224 ? 96.040  91.370  100.965 1.00 50.17  ? 224 ASP R CA  1 
ATOM 6104 C C   . ASP D 4 224 ? 95.976  92.825  100.512 1.00 60.09  ? 224 ASP R C   1 
ATOM 6105 O O   . ASP D 4 224 ? 95.825  93.084  99.314  1.00 66.24  ? 224 ASP R O   1 
ATOM 6106 C CB  . ASP D 4 224 ? 94.631  90.789  101.069 1.00 49.18  ? 224 ASP R CB  1 
ATOM 6107 N N   . GLN D 4 225 ? 96.077  93.776  101.442 1.00 51.85  ? 225 GLN R N   1 
ATOM 6108 C CA  . GLN D 4 225 ? 96.064  95.191  101.089 1.00 47.51  ? 225 GLN R CA  1 
ATOM 6109 C C   . GLN D 4 225 ? 97.396  95.624  100.484 1.00 53.60  ? 225 GLN R C   1 
ATOM 6110 O O   . GLN D 4 225 ? 97.438  96.201  99.387  1.00 62.60  ? 225 GLN R O   1 
ATOM 6111 C CB  . GLN D 4 225 ? 95.728  96.021  102.325 1.00 38.41  ? 225 GLN R CB  1 
ATOM 6112 C CG  . GLN D 4 225 ? 95.487  97.477  102.053 1.00 46.72  ? 225 GLN R CG  1 
ATOM 6113 C CD  . GLN D 4 225 ? 94.920  98.191  103.256 1.00 55.05  ? 225 GLN R CD  1 
ATOM 6114 O OE1 . GLN D 4 225 ? 93.946  97.739  103.853 1.00 57.25  ? 225 GLN R OE1 1 
ATOM 6115 N NE2 . GLN D 4 225 ? 95.530  99.311  103.623 1.00 58.83  ? 225 GLN R NE2 1 
ATOM 6116 N N   . ILE D 4 226 ? 98.492  95.394  101.209 1.00 38.50  ? 226 ILE R N   1 
ATOM 6117 C CA  . ILE D 4 226 ? 99.839  95.710  100.745 1.00 37.73  ? 226 ILE R CA  1 
ATOM 6118 C C   . ILE D 4 226 ? 100.061 95.102  99.369  1.00 48.70  ? 226 ILE R C   1 
ATOM 6119 O O   . ILE D 4 226 ? 100.692 95.715  98.496  1.00 61.06  ? 226 ILE R O   1 
ATOM 6120 C CB  . ILE D 4 226 ? 100.905 95.214  101.739 1.00 44.00  ? 226 ILE R CB  1 
ATOM 6121 C CG1 . ILE D 4 226 ? 100.715 95.872  103.102 1.00 46.81  ? 226 ILE R CG1 1 
ATOM 6122 C CG2 . ILE D 4 226 ? 102.296 95.491  101.219 1.00 44.71  ? 226 ILE R CG2 1 
ATOM 6123 C CD1 . ILE D 4 226 ? 101.160 97.311  103.152 1.00 47.22  ? 226 ILE R CD1 1 
ATOM 6124 N N   . GLN D 4 227 ? 99.537  93.893  99.164  1.00 38.05  ? 227 GLN R N   1 
ATOM 6125 C CA  . GLN D 4 227 ? 99.660  93.252  97.863  1.00 46.82  ? 227 GLN R CA  1 
ATOM 6126 C C   . GLN D 4 227 ? 98.950  94.056  96.784  1.00 55.46  ? 227 GLN R C   1 
ATOM 6127 O O   . GLN D 4 227 ? 99.495  94.265  95.692  1.00 62.71  ? 227 GLN R O   1 
ATOM 6128 C CB  . GLN D 4 227 ? 99.109  91.833  97.931  1.00 47.84  ? 227 GLN R CB  1 
ATOM 6129 C CG  . GLN D 4 227 ? 99.157  91.094  96.621  1.00 53.11  ? 227 GLN R CG  1 
ATOM 6130 C CD  . GLN D 4 227 ? 99.239  89.602  96.808  1.00 60.73  ? 227 GLN R CD  1 
ATOM 6131 O OE1 . GLN D 4 227 ? 99.902  89.117  97.722  1.00 63.92  ? 227 GLN R OE1 1 
ATOM 6132 N NE2 . GLN D 4 227 ? 98.565  88.860  95.940  1.00 58.37  ? 227 GLN R NE2 1 
ATOM 6133 N N   . ARG D 4 228 ? 97.737  94.529  97.075  1.00 49.68  ? 228 ARG R N   1 
ATOM 6134 C CA  . ARG D 4 228 ? 97.017  95.339  96.102  1.00 42.39  ? 228 ARG R CA  1 
ATOM 6135 C C   . ARG D 4 228 ? 97.794  96.601  95.765  1.00 46.33  ? 228 ARG R C   1 
ATOM 6136 O O   . ARG D 4 228 ? 97.928  96.958  94.589  1.00 55.08  ? 228 ARG R O   1 
ATOM 6137 C CB  . ARG D 4 228 ? 95.624  95.684  96.623  1.00 36.01  ? 228 ARG R CB  1 
ATOM 6138 N N   . LEU D 4 229 ? 98.350  97.269  96.777  1.00 39.03  ? 229 LEU R N   1 
ATOM 6139 C CA  . LEU D 4 229 ? 99.111  98.488  96.515  1.00 43.48  ? 229 LEU R CA  1 
ATOM 6140 C C   . LEU D 4 229 ? 100.343 98.215  95.657  1.00 47.81  ? 229 LEU R C   1 
ATOM 6141 O O   . LEU D 4 229 ? 100.629 98.962  94.711  1.00 53.69  ? 229 LEU R O   1 
ATOM 6142 C CB  . LEU D 4 229 ? 99.514  99.151  97.826  1.00 34.35  ? 229 LEU R CB  1 
ATOM 6143 C CG  . LEU D 4 229 ? 100.385 100.394 97.688  1.00 41.77  ? 229 LEU R CG  1 
ATOM 6144 C CD1 . LEU D 4 229 ? 99.728  101.410 96.775  1.00 48.40  ? 229 LEU R CD1 1 
ATOM 6145 C CD2 . LEU D 4 229 ? 100.649 101.000 99.044  1.00 49.86  ? 229 LEU R CD2 1 
ATOM 6146 N N   . VAL D 4 230 ? 101.079 97.145  95.960  1.00 39.81  ? 230 VAL R N   1 
ATOM 6147 C CA  . VAL D 4 230 ? 102.319 96.869  95.240  1.00 41.79  ? 230 VAL R CA  1 
ATOM 6148 C C   . VAL D 4 230 ? 102.033 96.514  93.786  1.00 47.61  ? 230 VAL R C   1 
ATOM 6149 O O   . VAL D 4 230 ? 102.667 97.048  92.858  1.00 62.08  ? 230 VAL R O   1 
ATOM 6150 C CB  . VAL D 4 230 ? 103.107 95.756  95.948  1.00 48.45  ? 230 VAL R CB  1 
ATOM 6151 C CG1 . VAL D 4 230 ? 104.131 95.153  95.011  1.00 48.60  ? 230 VAL R CG1 1 
ATOM 6152 C CG2 . VAL D 4 230 ? 103.779 96.305  97.184  1.00 48.73  ? 230 VAL R CG2 1 
ATOM 6153 N N   . LEU D 4 231 ? 101.081 95.604  93.560  1.00 41.59  ? 231 LEU R N   1 
ATOM 6154 C CA  . LEU D 4 231 ? 100.722 95.270  92.186  1.00 47.13  ? 231 LEU R CA  1 
ATOM 6155 C C   . LEU D 4 231 ? 100.177 96.479  91.440  1.00 54.39  ? 231 LEU R C   1 
ATOM 6156 O O   . LEU D 4 231 ? 100.472 96.660  90.254  1.00 64.59  ? 231 LEU R O   1 
ATOM 6157 C CB  . LEU D 4 231 ? 99.734  94.105  92.145  1.00 48.33  ? 231 LEU R CB  1 
ATOM 6158 C CG  . LEU D 4 231 ? 100.301 92.693  92.319  1.00 55.56  ? 231 LEU R CG  1 
ATOM 6159 C CD1 . LEU D 4 231 ? 100.782 92.380  93.721  1.00 54.53  ? 231 LEU R CD1 1 
ATOM 6160 C CD2 . LEU D 4 231 ? 99.267  91.668  91.875  1.00 52.25  ? 231 LEU R CD2 1 
ATOM 6161 N N   . SER D 4 232 ? 99.399  97.332  92.112  1.00 41.08  ? 232 SER R N   1 
ATOM 6162 C CA  . SER D 4 232 ? 98.897  98.526  91.447  1.00 41.50  ? 232 SER R CA  1 
ATOM 6163 C C   . SER D 4 232 ? 100.038 99.429  91.005  1.00 45.17  ? 232 SER R C   1 
ATOM 6164 O O   . SER D 4 232 ? 100.041 99.926  89.871  1.00 52.21  ? 232 SER R O   1 
ATOM 6165 C CB  . SER D 4 232 ? 97.942  99.278  92.370  1.00 46.40  ? 232 SER R CB  1 
ATOM 6166 N N   . THR D 4 233 ? 101.026 99.640  91.878  1.00 37.87  ? 233 THR R N   1 
ATOM 6167 C CA  . THR D 4 233 ? 102.155 100.497 91.528  1.00 42.80  ? 233 THR R CA  1 
ATOM 6168 C C   . THR D 4 233 ? 102.902 99.956  90.314  1.00 48.40  ? 233 THR R C   1 
ATOM 6169 O O   . THR D 4 233 ? 103.132 100.680 89.331  1.00 53.26  ? 233 THR R O   1 
ATOM 6170 C CB  . THR D 4 233 ? 103.102 100.629 92.718  1.00 45.02  ? 233 THR R CB  1 
ATOM 6171 O OG1 . THR D 4 233 ? 102.467 101.379 93.758  1.00 50.08  ? 233 THR R OG1 1 
ATOM 6172 C CG2 . THR D 4 233 ? 104.372 101.335 92.305  1.00 46.33  ? 233 THR R CG2 1 
ATOM 6173 N N   . VAL D 4 234 ? 103.266 98.673  90.354  1.00 38.38  ? 234 VAL R N   1 
ATOM 6174 C CA  . VAL D 4 234 ? 104.040 98.104  89.254  1.00 31.52  ? 234 VAL R CA  1 
ATOM 6175 C C   . VAL D 4 234 ? 103.239 98.133  87.954  1.00 48.88  ? 234 VAL R C   1 
ATOM 6176 O O   . VAL D 4 234 ? 103.767 98.492  86.890  1.00 62.31  ? 234 VAL R O   1 
ATOM 6177 C CB  . VAL D 4 234 ? 104.503 96.682  89.609  1.00 39.62  ? 234 VAL R CB  1 
ATOM 6178 C CG1 . VAL D 4 234 ? 105.008 95.964  88.376  1.00 46.00  ? 234 VAL R CG1 1 
ATOM 6179 C CG2 . VAL D 4 234 ? 105.583 96.741  90.664  1.00 46.72  ? 234 VAL R CG2 1 
ATOM 6180 N N   . VAL D 4 235 ? 101.954 97.776  88.015  1.00 42.31  ? 235 VAL R N   1 
ATOM 6181 C CA  . VAL D 4 235 ? 101.143 97.707  86.805  1.00 32.10  ? 235 VAL R CA  1 
ATOM 6182 C C   . VAL D 4 235 ? 100.949 99.088  86.193  1.00 42.04  ? 235 VAL R C   1 
ATOM 6183 O O   . VAL D 4 235 ? 101.005 99.245  84.967  1.00 50.14  ? 235 VAL R O   1 
ATOM 6184 C CB  . VAL D 4 235 ? 99.797  97.028  87.103  1.00 39.89  ? 235 VAL R CB  1 
ATOM 6185 C CG1 . VAL D 4 235 ? 98.819  97.282  85.974  1.00 46.14  ? 235 VAL R CG1 1 
ATOM 6186 C CG2 . VAL D 4 235 ? 99.994  95.541  87.304  1.00 46.14  ? 235 VAL R CG2 1 
ATOM 6187 N N   . ILE D 4 236 ? 100.702 100.109 87.018  1.00 48.51  ? 236 ILE R N   1 
ATOM 6188 C CA  . ILE D 4 236 ? 100.495 101.443 86.461  1.00 45.40  ? 236 ILE R CA  1 
ATOM 6189 C C   . ILE D 4 236 ? 101.790 101.969 85.854  1.00 47.52  ? 236 ILE R C   1 
ATOM 6190 O O   . ILE D 4 236 ? 101.775 102.623 84.803  1.00 50.85  ? 236 ILE R O   1 
ATOM 6191 C CB  . ILE D 4 236 ? 99.908  102.401 87.517  1.00 36.27  ? 236 ILE R CB  1 
ATOM 6192 C CG1 . ILE D 4 236 ? 99.453  103.699 86.862  1.00 42.35  ? 236 ILE R CG1 1 
ATOM 6193 C CG2 . ILE D 4 236 ? 100.917 102.747 88.566  1.00 41.82  ? 236 ILE R CG2 1 
ATOM 6194 C CD1 . ILE D 4 236 ? 98.583  104.548 87.757  1.00 47.57  ? 236 ILE R CD1 1 
ATOM 6195 N N   . PHE D 4 237 ? 102.934 101.671 86.481  1.00 52.73  ? 237 PHE R N   1 
ATOM 6196 C CA  . PHE D 4 237 ? 104.211 102.053 85.882  1.00 50.22  ? 237 PHE R CA  1 
ATOM 6197 C C   . PHE D 4 237 ? 104.389 101.403 84.516  1.00 50.29  ? 237 PHE R C   1 
ATOM 6198 O O   . PHE D 4 237 ? 104.794 102.060 83.544  1.00 55.67  ? 237 PHE R O   1 
ATOM 6199 C CB  . PHE D 4 237 ? 105.357 101.666 86.815  1.00 46.95  ? 237 PHE R CB  1 
ATOM 6200 C CG  . PHE D 4 237 ? 106.720 101.899 86.240  1.00 49.60  ? 237 PHE R CG  1 
ATOM 6201 C CD1 . PHE D 4 237 ? 107.311 103.142 86.304  1.00 54.42  ? 237 PHE R CD1 1 
ATOM 6202 C CD2 . PHE D 4 237 ? 107.422 100.865 85.651  1.00 51.87  ? 237 PHE R CD2 1 
ATOM 6203 C CE1 . PHE D 4 237 ? 108.570 103.347 85.782  1.00 57.87  ? 237 PHE R CE1 1 
ATOM 6204 C CE2 . PHE D 4 237 ? 108.678 101.069 85.127  1.00 52.51  ? 237 PHE R CE2 1 
ATOM 6205 C CZ  . PHE D 4 237 ? 109.250 102.307 85.193  1.00 56.97  ? 237 PHE R CZ  1 
ATOM 6206 N N   . LEU D 4 238 ? 104.089 100.107 84.423  1.00 48.01  ? 238 LEU R N   1 
ATOM 6207 C CA  . LEU D 4 238 ? 104.237 99.412  83.150  1.00 50.95  ? 238 LEU R CA  1 
ATOM 6208 C C   . LEU D 4 238 ? 103.316 100.006 82.094  1.00 59.35  ? 238 LEU R C   1 
ATOM 6209 O O   . LEU D 4 238 ? 103.745 100.290 80.971  1.00 66.12  ? 238 LEU R O   1 
ATOM 6210 C CB  . LEU D 4 238 ? 103.960 97.921  83.326  1.00 51.56  ? 238 LEU R CB  1 
ATOM 6211 C CG  . LEU D 4 238 ? 105.162 97.069  83.712  1.00 56.27  ? 238 LEU R CG  1 
ATOM 6212 C CD1 . LEU D 4 238 ? 104.863 95.599  83.494  1.00 58.89  ? 238 LEU R CD1 1 
ATOM 6213 C CD2 . LEU D 4 238 ? 106.366 97.494  82.910  1.00 56.71  ? 238 LEU R CD2 1 
ATOM 6214 N N   . ALA D 4 239 ? 102.051 100.229 82.449  1.00 52.81  ? 239 ALA R N   1 
ATOM 6215 C CA  . ALA D 4 239 ? 101.100 100.764 81.483  1.00 46.02  ? 239 ALA R CA  1 
ATOM 6216 C C   . ALA D 4 239 ? 101.472 102.172 81.057  1.00 47.42  ? 239 ALA R C   1 
ATOM 6217 O O   . ALA D 4 239 ? 101.143 102.589 79.942  1.00 54.62  ? 239 ALA R O   1 
ATOM 6218 C CB  . ALA D 4 239 ? 99.686  100.739 82.064  1.00 50.39  ? 239 ALA R CB  1 
ATOM 6219 N N   . CYS D 4 240 ? 102.153 102.921 81.923  1.00 53.72  ? 240 CYS R N   1 
ATOM 6220 C CA  . CYS D 4 240 ? 102.600 104.253 81.536  1.00 55.25  ? 240 CYS R CA  1 
ATOM 6221 C C   . CYS D 4 240 ? 103.786 104.203 80.581  1.00 57.17  ? 240 CYS R C   1 
ATOM 6222 O O   . CYS D 4 240 ? 103.836 104.974 79.618  1.00 59.64  ? 240 CYS R O   1 
ATOM 6223 C CB  . CYS D 4 240 ? 102.963 105.072 82.774  1.00 58.47  ? 240 CYS R CB  1 
ATOM 6224 S SG  . CYS D 4 240 ? 101.572 105.832 83.618  1.00 68.84  ? 240 CYS R SG  1 
ATOM 6225 N N   . PHE D 4 241 ? 104.750 103.312 80.820  1.00 57.52  ? 241 PHE R N   1 
ATOM 6226 C CA  . PHE D 4 241 ? 106.030 103.433 80.131  1.00 54.65  ? 241 PHE R CA  1 
ATOM 6227 C C   . PHE D 4 241 ? 106.297 102.400 79.046  1.00 58.48  ? 241 PHE R C   1 
ATOM 6228 O O   . PHE D 4 241 ? 106.925 102.745 78.045  1.00 67.60  ? 241 PHE R O   1 
ATOM 6229 C CB  . PHE D 4 241 ? 107.183 103.384 81.137  1.00 55.08  ? 241 PHE R CB  1 
ATOM 6230 C CG  . PHE D 4 241 ? 107.489 104.704 81.768  1.00 55.20  ? 241 PHE R CG  1 
ATOM 6231 C CD1 . PHE D 4 241 ? 108.193 105.665 81.079  1.00 61.74  ? 241 PHE R CD1 1 
ATOM 6232 C CD2 . PHE D 4 241 ? 107.082 104.983 83.054  1.00 53.70  ? 241 PHE R CD2 1 
ATOM 6233 C CE1 . PHE D 4 241 ? 108.477 106.877 81.659  1.00 60.15  ? 241 PHE R CE1 1 
ATOM 6234 C CE2 . PHE D 4 241 ? 107.367 106.195 83.635  1.00 55.74  ? 241 PHE R CE2 1 
ATOM 6235 C CZ  . PHE D 4 241 ? 108.063 107.139 82.938  1.00 55.67  ? 241 PHE R CZ  1 
ATOM 6236 N N   . LEU D 4 242 ? 105.860 101.152 79.207  1.00 53.41  ? 242 LEU R N   1 
ATOM 6237 C CA  . LEU D 4 242 ? 106.331 100.081 78.328  1.00 52.73  ? 242 LEU R CA  1 
ATOM 6238 C C   . LEU D 4 242 ? 106.009 100.299 76.853  1.00 55.72  ? 242 LEU R C   1 
ATOM 6239 O O   . LEU D 4 242 ? 106.909 100.097 76.016  1.00 66.68  ? 242 LEU R O   1 
ATOM 6240 C CB  . LEU D 4 242 ? 105.785 98.741  78.832  1.00 60.59  ? 242 LEU R CB  1 
ATOM 6241 C CG  . LEU D 4 242 ? 106.267 97.433  78.202  1.00 61.96  ? 242 LEU R CG  1 
ATOM 6242 C CD1 . LEU D 4 242 ? 106.154 96.311  79.218  1.00 58.74  ? 242 LEU R CD1 1 
ATOM 6243 C CD2 . LEU D 4 242 ? 105.466 97.074  76.962  1.00 58.53  ? 242 LEU R CD2 1 
ATOM 6244 N N   . PRO D 4 243 ? 104.787 100.671 76.455  1.00 43.10  ? 243 PRO R N   1 
ATOM 6245 C CA  . PRO D 4 243 ? 104.519 100.816 75.017  1.00 49.07  ? 243 PRO R CA  1 
ATOM 6246 C C   . PRO D 4 243 ? 105.390 101.855 74.343  1.00 63.32  ? 243 PRO R C   1 
ATOM 6247 O O   . PRO D 4 243 ? 105.772 101.667 73.179  1.00 68.01  ? 243 PRO R O   1 
ATOM 6248 C CB  . PRO D 4 243 ? 103.038 101.207 74.976  1.00 53.93  ? 243 PRO R CB  1 
ATOM 6249 C CG  . PRO D 4 243 ? 102.776 101.807 76.288  1.00 56.64  ? 243 PRO R CG  1 
ATOM 6250 C CD  . PRO D 4 243 ? 103.602 101.026 77.251  1.00 50.79  ? 243 PRO R CD  1 
ATOM 6251 N N   . TYR D 4 244 ? 105.730 102.941 75.043  1.00 68.24  ? 244 TYR R N   1 
ATOM 6252 C CA  . TYR D 4 244 ? 106.600 103.955 74.459  1.00 63.32  ? 244 TYR R CA  1 
ATOM 6253 C C   . TYR D 4 244 ? 107.948 103.363 74.090  1.00 62.94  ? 244 TYR R C   1 
ATOM 6254 O O   . TYR D 4 244 ? 108.450 103.573 72.983  1.00 67.73  ? 244 TYR R O   1 
ATOM 6255 C CB  . TYR D 4 244 ? 106.778 105.120 75.429  1.00 58.01  ? 244 TYR R CB  1 
ATOM 6256 C CG  . TYR D 4 244 ? 107.782 106.148 74.971  1.00 59.19  ? 244 TYR R CG  1 
ATOM 6257 C CD1 . TYR D 4 244 ? 107.711 106.698 73.702  1.00 62.31  ? 244 TYR R CD1 1 
ATOM 6258 C CD2 . TYR D 4 244 ? 108.791 106.576 75.807  1.00 59.20  ? 244 TYR R CD2 1 
ATOM 6259 C CE1 . TYR D 4 244 ? 108.623 107.640 73.284  1.00 60.84  ? 244 TYR R CE1 1 
ATOM 6260 C CE2 . TYR D 4 244 ? 109.703 107.513 75.396  1.00 56.09  ? 244 TYR R CE2 1 
ATOM 6261 C CZ  . TYR D 4 244 ? 109.616 108.041 74.135  1.00 59.47  ? 244 TYR R CZ  1 
ATOM 6262 O OH  . TYR D 4 244 ? 110.527 108.978 73.725  1.00 66.28  ? 244 TYR R OH  1 
ATOM 6263 N N   . HIS D 4 245 ? 108.538 102.596 75.003  1.00 54.14  ? 245 HIS R N   1 
ATOM 6264 C CA  . HIS D 4 245 ? 109.854 102.033 74.746  1.00 60.17  ? 245 HIS R CA  1 
ATOM 6265 C C   . HIS D 4 245 ? 109.794 100.947 73.680  1.00 61.87  ? 245 HIS R C   1 
ATOM 6266 O O   . HIS D 4 245 ? 110.713 100.823 72.857  1.00 67.89  ? 245 HIS R O   1 
ATOM 6267 C CB  . HIS D 4 245 ? 110.445 101.499 76.044  1.00 58.94  ? 245 HIS R CB  1 
ATOM 6268 C CG  . HIS D 4 245 ? 110.871 102.571 76.994  1.00 56.20  ? 245 HIS R CG  1 
ATOM 6269 N ND1 . HIS D 4 245 ? 110.163 102.879 78.133  1.00 58.04  ? 245 HIS R ND1 1 
ATOM 6270 C CD2 . HIS D 4 245 ? 111.932 103.409 76.973  1.00 59.69  ? 245 HIS R CD2 1 
ATOM 6271 C CE1 . HIS D 4 245 ? 110.770 103.861 78.774  1.00 61.00  ? 245 HIS R CE1 1 
ATOM 6272 N NE2 . HIS D 4 245 ? 111.846 104.201 78.091  1.00 62.32  ? 245 HIS R NE2 1 
ATOM 6273 N N   . VAL D 4 246 ? 108.721 100.157 73.671  1.00 58.84  ? 246 VAL R N   1 
ATOM 6274 C CA  . VAL D 4 246 ? 108.586 99.128  72.645  1.00 61.78  ? 246 VAL R CA  1 
ATOM 6275 C C   . VAL D 4 246 ? 108.497 99.768  71.265  1.00 63.92  ? 246 VAL R C   1 
ATOM 6276 O O   . VAL D 4 246 ? 109.178 99.349  70.321  1.00 72.29  ? 246 VAL R O   1 
ATOM 6277 C CB  . VAL D 4 246 ? 107.372 98.231  72.936  1.00 65.23  ? 246 VAL R CB  1 
ATOM 6278 C CG1 . VAL D 4 246 ? 106.925 97.510  71.674  1.00 66.93  ? 246 VAL R CG1 1 
ATOM 6279 C CG2 . VAL D 4 246 ? 107.707 97.232  74.031  1.00 68.72  ? 246 VAL R CG2 1 
ATOM 6280 N N   . LEU D 4 247 ? 107.677 100.815 71.132  1.00 63.72  ? 247 LEU R N   1 
ATOM 6281 C CA  . LEU D 4 247 ? 107.570 101.492 69.844  1.00 68.58  ? 247 LEU R CA  1 
ATOM 6282 C C   . LEU D 4 247 ? 108.857 102.223 69.493  1.00 73.86  ? 247 LEU R C   1 
ATOM 6283 O O   . LEU D 4 247 ? 109.198 102.349 68.311  1.00 76.39  ? 247 LEU R O   1 
ATOM 6284 C CB  . LEU D 4 247 ? 106.392 102.462 69.851  1.00 71.24  ? 247 LEU R CB  1 
ATOM 6285 N N   . LEU D 4 248 ? 109.585 102.701 70.503  1.00 70.08  ? 248 LEU R N   1 
ATOM 6286 C CA  . LEU D 4 248 ? 110.877 103.330 70.266  1.00 67.21  ? 248 LEU R CA  1 
ATOM 6287 C C   . LEU D 4 248 ? 111.848 102.350 69.623  1.00 66.68  ? 248 LEU R C   1 
ATOM 6288 O O   . LEU D 4 248 ? 112.491 102.667 68.615  1.00 71.17  ? 248 LEU R O   1 
ATOM 6289 C CB  . LEU D 4 248 ? 111.416 103.875 71.589  1.00 65.98  ? 248 LEU R CB  1 
ATOM 6290 C CG  . LEU D 4 248 ? 112.671 104.732 71.645  1.00 65.88  ? 248 LEU R CG  1 
ATOM 6291 C CD1 . LEU D 4 248 ? 112.598 105.638 72.841  1.00 64.34  ? 248 LEU R CD1 1 
ATOM 6292 C CD2 . LEU D 4 248 ? 113.875 103.833 71.775  1.00 72.87  ? 248 LEU R CD2 1 
ATOM 6293 N N   . LEU D 4 249 ? 111.959 101.146 70.185  1.00 68.38  ? 249 LEU R N   1 
ATOM 6294 C CA  . LEU D 4 249 ? 112.780 100.128 69.537  1.00 67.00  ? 249 LEU R CA  1 
ATOM 6295 C C   . LEU D 4 249 ? 112.256 99.808  68.147  1.00 71.51  ? 249 LEU R C   1 
ATOM 6296 O O   . LEU D 4 249 ? 113.038 99.668  67.200  1.00 77.71  ? 249 LEU R O   1 
ATOM 6297 C CB  . LEU D 4 249 ? 112.836 98.846  70.360  1.00 70.55  ? 249 LEU R CB  1 
ATOM 6298 C CG  . LEU D 4 249 ? 113.502 98.786  71.722  1.00 72.69  ? 249 LEU R CG  1 
ATOM 6299 C CD1 . LEU D 4 249 ? 113.238 97.411  72.281  1.00 72.08  ? 249 LEU R CD1 1 
ATOM 6300 C CD2 . LEU D 4 249 ? 114.991 99.047  71.607  1.00 70.71  ? 249 LEU R CD2 1 
ATOM 6301 N N   . VAL D 4 250 ? 110.936 99.671  68.009  1.00 74.65  ? 250 VAL R N   1 
ATOM 6302 C CA  . VAL D 4 250 ? 110.366 99.293  66.720  1.00 75.55  ? 250 VAL R CA  1 
ATOM 6303 C C   . VAL D 4 250 ? 110.779 100.289 65.652  1.00 78.32  ? 250 VAL R C   1 
ATOM 6304 O O   . VAL D 4 250 ? 111.109 99.912  64.522  1.00 79.75  ? 250 VAL R O   1 
ATOM 6305 C CB  . VAL D 4 250 ? 108.835 99.173  66.822  1.00 73.70  ? 250 VAL R CB  1 
ATOM 6306 N N   . ARG D 4 251 ? 110.783 101.575 65.997  1.00 76.79  ? 251 ARG R N   1 
ATOM 6307 C CA  . ARG D 4 251 ? 111.190 102.590 65.035  1.00 79.97  ? 251 ARG R CA  1 
ATOM 6308 C C   . ARG D 4 251 ? 112.698 102.574 64.815  1.00 76.62  ? 251 ARG R C   1 
ATOM 6309 O O   . ARG D 4 251 ? 113.165 102.750 63.685  1.00 80.22  ? 251 ARG R O   1 
ATOM 6310 C CB  . ARG D 4 251 ? 110.727 103.968 65.501  1.00 81.01  ? 251 ARG R CB  1 
ATOM 6311 C CG  . ARG D 4 251 ? 110.722 105.024 64.409  1.00 81.54  ? 251 ARG R CG  1 
ATOM 6312 C CD  . ARG D 4 251 ? 109.556 105.974 64.595  1.00 80.35  ? 251 ARG R CD  1 
ATOM 6313 N NE  . ARG D 4 251 ? 109.705 106.791 65.792  1.00 75.78  ? 251 ARG R NE  1 
ATOM 6314 C CZ  . ARG D 4 251 ? 110.198 108.022 65.789  1.00 75.15  ? 251 ARG R CZ  1 
ATOM 6315 N NH1 . ARG D 4 251 ? 110.567 108.583 64.651  1.00 77.26  ? 251 ARG R NH1 1 
ATOM 6316 N NH2 . ARG D 4 251 ? 110.304 108.698 66.920  1.00 72.47  ? 251 ARG R NH2 1 
ATOM 6317 N N   . SER D 4 252 ? 113.476 102.357 65.876  1.00 73.57  ? 252 SER R N   1 
ATOM 6318 C CA  . SER D 4 252 ? 114.921 102.517 65.764  1.00 74.77  ? 252 SER R CA  1 
ATOM 6319 C C   . SER D 4 252 ? 115.601 101.358 65.046  1.00 73.30  ? 252 SER R C   1 
ATOM 6320 O O   . SER D 4 252 ? 116.578 101.581 64.325  1.00 75.46  ? 252 SER R O   1 
ATOM 6321 C CB  . SER D 4 252 ? 115.538 102.693 67.151  1.00 81.47  ? 252 SER R CB  1 
ATOM 6322 O OG  . SER D 4 252 ? 115.247 101.586 67.985  1.00 82.34  ? 252 SER R OG  1 
ATOM 6323 N N   . VAL D 4 253 ? 115.121 100.128 65.217  1.00 83.11  ? 253 VAL R N   1 
ATOM 6324 C CA  . VAL D 4 253 ? 115.876 98.975  64.735  1.00 87.31  ? 253 VAL R CA  1 
ATOM 6325 C C   . VAL D 4 253 ? 115.676 98.755  63.242  1.00 87.21  ? 253 VAL R C   1 
ATOM 6326 O O   . VAL D 4 253 ? 116.631 98.846  62.464  1.00 88.39  ? 253 VAL R O   1 
ATOM 6327 C CB  . VAL D 4 253 ? 115.516 97.701  65.518  1.00 88.68  ? 253 VAL R CB  1 
ATOM 6328 C CG1 . VAL D 4 253 ? 116.472 96.578  65.155  1.00 87.56  ? 253 VAL R CG1 1 
ATOM 6329 C CG2 . VAL D 4 253 ? 115.587 97.962  67.009  1.00 85.38  ? 253 VAL R CG2 1 
ATOM 6330 N N   . TRP D 4 254 ? 114.448 98.466  62.822  1.00 88.08  ? 254 TRP R N   1 
ATOM 6331 C CA  . TRP D 4 254 ? 114.189 98.145  61.422  1.00 89.51  ? 254 TRP R CA  1 
ATOM 6332 C C   . TRP D 4 254 ? 112.971 98.893  60.905  1.00 89.79  ? 254 TRP R C   1 
ATOM 6333 O O   . TRP D 4 254 ? 112.183 98.370  60.112  1.00 93.09  ? 254 TRP R O   1 
ATOM 6334 C CB  . TRP D 4 254 ? 114.054 96.635  61.216  1.00 88.57  ? 254 TRP R CB  1 
ATOM 6335 C CG  . TRP D 4 254 ? 112.790 96.015  61.732  1.00 88.55  ? 254 TRP R CG  1 
ATOM 6336 C CD1 . TRP D 4 254 ? 112.380 95.946  63.029  1.00 89.52  ? 254 TRP R CD1 1 
ATOM 6337 C CD2 . TRP D 4 254 ? 111.780 95.358  60.957  1.00 89.83  ? 254 TRP R CD2 1 
ATOM 6338 N NE1 . TRP D 4 254 ? 111.174 95.296  63.111  1.00 91.06  ? 254 TRP R NE1 1 
ATOM 6339 C CE2 . TRP D 4 254 ? 110.783 94.925  61.851  1.00 92.05  ? 254 TRP R CE2 1 
ATOM 6340 C CE3 . TRP D 4 254 ? 111.619 95.099  59.592  1.00 89.67  ? 254 TRP R CE3 1 
ATOM 6341 C CZ2 . TRP D 4 254 ? 109.642 94.247  61.427  1.00 89.33  ? 254 TRP R CZ2 1 
ATOM 6342 C CZ3 . TRP D 4 254 ? 110.485 94.424  59.173  1.00 89.23  ? 254 TRP R CZ3 1 
ATOM 6343 C CH2 . TRP D 4 254 ? 109.512 94.007  60.087  1.00 88.82  ? 254 TRP R CH2 1 
ATOM 6344 N N   . GLU D 4 255 ? 112.831 100.153 61.305  1.00 87.79  ? 255 GLU R N   1 
ATOM 6345 C CA  . GLU D 4 255 ? 111.733 100.971 60.790  1.00 90.13  ? 255 GLU R CA  1 
ATOM 6346 C C   . GLU D 4 255 ? 112.240 102.365 60.451  1.00 88.16  ? 255 GLU R C   1 
ATOM 6347 O O   . GLU D 4 255 ? 111.908 103.332 61.138  1.00 89.16  ? 255 GLU R O   1 
ATOM 6348 C CB  . GLU D 4 255 ? 110.590 101.051 61.800  1.00 90.31  ? 255 GLU R CB  1 
ATOM 6349 N N   . ALA D 4 256 ? 113.054 102.478 59.405  1.00 80.76  ? 256 ALA R N   1 
ATOM 6350 C CA  . ALA D 4 256 ? 113.647 103.769 59.072  1.00 82.53  ? 256 ALA R CA  1 
ATOM 6351 C C   . ALA D 4 256 ? 113.191 104.347 57.733  1.00 87.80  ? 256 ALA R C   1 
ATOM 6352 O O   . ALA D 4 256 ? 112.977 105.555 57.626  1.00 88.34  ? 256 ALA R O   1 
ATOM 6353 C CB  . ALA D 4 256 ? 115.163 103.660 59.097  1.00 83.74  ? 256 ALA R CB  1 
ATOM 6354 N N   . SER D 4 257 ? 113.041 103.507 56.714  1.00 99.52  ? 257 SER R N   1 
ATOM 6355 C CA  . SER D 4 257 ? 112.678 104.015 55.393  1.00 97.50  ? 257 SER R CA  1 
ATOM 6356 C C   . SER D 4 257 ? 111.484 104.948 55.500  1.00 98.67  ? 257 SER R C   1 
ATOM 6357 O O   . SER D 4 257 ? 110.552 104.676 56.258  1.00 99.75  ? 257 SER R O   1 
ATOM 6358 C CB  . SER D 4 257 ? 112.363 102.867 54.438  1.00 96.44  ? 257 SER R CB  1 
ATOM 6359 O OG  . SER D 4 257 ? 111.248 102.122 54.895  1.00 94.30  ? 257 SER R OG  1 
ATOM 6360 N N   . CYS D 4 258 ? 111.498 106.042 54.743  1.00 98.55  ? 258 CYS R N   1 
ATOM 6361 C CA  . CYS D 4 258 ? 110.423 107.034 54.861  1.00 100.29 ? 258 CYS R CA  1 
ATOM 6362 C C   . CYS D 4 258 ? 109.012 106.453 54.735  1.00 98.06  ? 258 CYS R C   1 
ATOM 6363 O O   . CYS D 4 258 ? 108.081 107.002 55.322  1.00 100.93 ? 258 CYS R O   1 
ATOM 6364 C CB  . CYS D 4 258 ? 110.615 108.201 53.863  1.00 30.00  ? 258 CYS R CB  1 
ATOM 6365 S SG  . CYS D 4 258 ? 109.173 109.298 53.697  1.00 30.00  ? 258 CYS R SG  1 
ATOM 6366 N N   . ASP D 4 259 ? 108.820 105.358 54.001  1.00 89.32  ? 259 ASP R N   1 
ATOM 6367 C CA  . ASP D 4 259 ? 107.438 104.897 53.865  1.00 93.50  ? 259 ASP R CA  1 
ATOM 6368 C C   . ASP D 4 259 ? 106.951 104.317 55.160  1.00 96.93  ? 259 ASP R C   1 
ATOM 6369 O O   . ASP D 4 259 ? 105.813 104.568 55.647  1.00 97.57  ? 259 ASP R O   1 
ATOM 6370 C CB  . ASP D 4 259 ? 107.335 103.842 52.766  1.00 92.52  ? 259 ASP R CB  1 
ATOM 6371 N N   . PHE D 4 260 ? 107.882 103.594 55.803  1.00 95.85  ? 260 PHE R N   1 
ATOM 6372 C CA  . PHE D 4 260 ? 107.679 102.995 57.116  1.00 93.65  ? 260 PHE R CA  1 
ATOM 6373 C C   . PHE D 4 260 ? 107.472 104.080 58.104  1.00 91.22  ? 260 PHE R C   1 
ATOM 6374 O O   . PHE D 4 260 ? 106.635 103.965 58.998  1.00 93.23  ? 260 PHE R O   1 
ATOM 6375 C CB  . PHE D 4 260 ? 108.895 102.196 57.557  1.00 30.00  ? 260 PHE R CB  1 
ATOM 6376 N N   . ALA D 4 261 ? 108.219 105.156 57.949  1.00 86.94  ? 261 ALA R N   1 
ATOM 6377 C CA  . ALA D 4 261 ? 108.115 106.239 58.850  1.00 90.98  ? 261 ALA R CA  1 
ATOM 6378 C C   . ALA D 4 261 ? 106.743 106.795 58.816  1.00 88.68  ? 261 ALA R C   1 
ATOM 6379 O O   . ALA D 4 261 ? 106.132 106.930 59.861  1.00 89.27  ? 261 ALA R O   1 
ATOM 6380 C CB  . ALA D 4 261 ? 109.135 107.313 58.500  1.00 91.15  ? 261 ALA R CB  1 
ATOM 6381 N N   . LYS D 4 262 ? 106.210 107.004 57.624  1.00 94.64  ? 262 LYS R N   1 
ATOM 6382 C CA  . LYS D 4 262 ? 104.873 107.518 57.542  1.00 99.50  ? 262 LYS R CA  1 
ATOM 6383 C C   . LYS D 4 262 ? 103.878 106.588 58.197  1.00 100.64 ? 262 LYS R C   1 
ATOM 6384 O O   . LYS D 4 262 ? 103.001 107.053 58.913  1.00 100.15 ? 262 LYS R O   1 
ATOM 6385 C CB  . LYS D 4 262 ? 104.463 107.758 56.092  1.00 96.84  ? 262 LYS R CB  1 
ATOM 6386 N N   . GLY D 4 263 ? 104.121 105.285 58.153  1.00 95.12  ? 263 GLY R N   1 
ATOM 6387 C CA  . GLY D 4 263 ? 103.247 104.340 58.837  1.00 92.78  ? 263 GLY R CA  1 
ATOM 6388 C C   . GLY D 4 263 ? 103.020 104.396 60.350  1.00 91.87  ? 263 GLY R C   1 
ATOM 6389 O O   . GLY D 4 263 ? 101.866 104.420 60.775  1.00 91.92  ? 263 GLY R O   1 
ATOM 6390 N N   . VAL D 4 264 ? 104.081 104.433 61.152  1.00 91.60  ? 264 VAL R N   1 
ATOM 6391 C CA  . VAL D 4 264 ? 103.910 104.374 62.614  1.00 93.78  ? 264 VAL R CA  1 
ATOM 6392 C C   . VAL D 4 264 ? 104.008 105.707 63.361  1.00 95.22  ? 264 VAL R C   1 
ATOM 6393 O O   . VAL D 4 264 ? 104.367 105.728 64.539  1.00 93.43  ? 264 VAL R O   1 
ATOM 6394 C CB  . VAL D 4 264 ? 104.935 103.405 63.242  1.00 94.77  ? 264 VAL R CB  1 
ATOM 6395 N N   . PHE D 4 265 ? 103.682 106.811 62.700  1.00 96.47  ? 265 PHE R N   1 
ATOM 6396 C CA  . PHE D 4 265 ? 103.693 108.107 63.374  1.00 93.89  ? 265 PHE R CA  1 
ATOM 6397 C C   . PHE D 4 265 ? 102.650 108.132 64.471  1.00 94.52  ? 265 PHE R C   1 
ATOM 6398 O O   . PHE D 4 265 ? 102.885 108.694 65.541  1.00 99.73  ? 265 PHE R O   1 
ATOM 6399 C CB  . PHE D 4 265 ? 103.432 109.229 62.366  1.00 98.08  ? 265 PHE R CB  1 
ATOM 6400 C CG  . PHE D 4 265 ? 103.280 110.587 62.990  1.00 97.68  ? 265 PHE R CG  1 
ATOM 6401 C CD1 . PHE D 4 265 ? 102.052 111.016 63.468  1.00 96.16  ? 265 PHE R CD1 1 
ATOM 6402 C CD2 . PHE D 4 265 ? 104.365 111.439 63.091  1.00 97.64  ? 265 PHE R CD2 1 
ATOM 6403 C CE1 . PHE D 4 265 ? 101.913 112.263 64.045  1.00 95.38  ? 265 PHE R CE1 1 
ATOM 6404 C CE2 . PHE D 4 265 ? 104.233 112.689 63.664  1.00 98.40  ? 265 PHE R CE2 1 
ATOM 6405 C CZ  . PHE D 4 265 ? 103.006 113.101 64.143  1.00 96.87  ? 265 PHE R CZ  1 
ATOM 6406 N N   . ASN D 4 266 ? 101.498 107.523 64.220  1.00 85.82  ? 266 ASN R N   1 
ATOM 6407 C CA  . ASN D 4 266 ? 100.446 107.513 65.163  1.00 89.66  ? 266 ASN R CA  1 
ATOM 6408 C C   . ASN D 4 266 ? 100.978 106.773 66.420  1.00 91.53  ? 266 ASN R C   1 
ATOM 6409 O O   . ASN D 4 266 ? 100.955 107.295 67.537  1.00 95.04  ? 266 ASN R O   1 
ATOM 6410 C CB  . ASN D 4 266 ? 99.149  106.984 64.594  1.00 85.54  ? 266 ASN R CB  1 
ATOM 6411 C CG  . ASN D 4 266 ? 98.367  108.053 63.877  1.00 88.22  ? 266 ASN R CG  1 
ATOM 6412 O OD1 . ASN D 4 266 ? 98.414  109.221 64.247  1.00 89.96  ? 266 ASN R OD1 1 
ATOM 6413 N ND2 . ASN D 4 266 ? 97.642  107.660 62.840  1.00 90.20  ? 266 ASN R ND2 1 
ATOM 6414 N N   . ALA D 4 267 ? 101.485 105.548 66.165  1.00 79.45  ? 267 ALA R N   1 
ATOM 6415 C CA  . ALA D 4 267 ? 101.862 104.698 67.287  1.00 82.21  ? 267 ALA R CA  1 
ATOM 6416 C C   . ALA D 4 267 ? 102.856 105.402 68.246  1.00 83.85  ? 267 ALA R C   1 
ATOM 6417 O O   . ALA D 4 267 ? 102.677 105.444 69.471  1.00 84.66  ? 267 ALA R O   1 
ATOM 6418 C CB  . ALA D 4 267 ? 102.419 103.380 66.823  1.00 82.03  ? 267 ALA R CB  1 
ATOM 6419 N N   . TYR D 4 268 ? 103.911 105.975 67.662  1.00 75.79  ? 268 TYR R N   1 
ATOM 6420 C CA  . TYR D 4 268 ? 104.935 106.613 68.478  1.00 75.20  ? 268 TYR R CA  1 
ATOM 6421 C C   . TYR D 4 268 ? 104.388 107.818 69.230  1.00 78.42  ? 268 TYR R C   1 
ATOM 6422 O O   . TYR D 4 268 ? 104.666 107.978 70.427  1.00 80.50  ? 268 TYR R O   1 
ATOM 6423 C CB  . TYR D 4 268 ? 106.118 107.030 67.610  1.00 73.52  ? 268 TYR R CB  1 
ATOM 6424 C CG  . TYR D 4 268 ? 107.201 107.741 68.379  1.00 72.57  ? 268 TYR R CG  1 
ATOM 6425 C CD1 . TYR D 4 268 ? 108.082 107.037 69.178  1.00 76.29  ? 268 TYR R CD1 1 
ATOM 6426 C CD2 . TYR D 4 268 ? 107.330 109.115 68.319  1.00 74.03  ? 268 TYR R CD2 1 
ATOM 6427 C CE1 . TYR D 4 268 ? 109.068 107.684 69.889  1.00 79.80  ? 268 TYR R CE1 1 
ATOM 6428 C CE2 . TYR D 4 268 ? 108.306 109.770 69.027  1.00 76.63  ? 268 TYR R CE2 1 
ATOM 6429 C CZ  . TYR D 4 268 ? 109.175 109.053 69.810  1.00 80.04  ? 268 TYR R CZ  1 
ATOM 6430 O OH  . TYR D 4 268 ? 110.157 109.708 70.516  1.00 79.51  ? 268 TYR R OH  1 
ATOM 6431 N N   . HIS D 4 269 ? 103.576 108.652 68.578  1.00 77.66  ? 269 HIS R N   1 
ATOM 6432 C CA  . HIS D 4 269 ? 103.058 109.802 69.309  1.00 76.30  ? 269 HIS R CA  1 
ATOM 6433 C C   . HIS D 4 269 ? 101.947 109.449 70.280  1.00 74.75  ? 269 HIS R C   1 
ATOM 6434 O O   . HIS D 4 269 ? 101.812 110.121 71.306  1.00 77.25  ? 269 HIS R O   1 
ATOM 6435 C CB  . HIS D 4 269 ? 102.609 110.901 68.348  1.00 78.25  ? 269 HIS R CB  1 
ATOM 6436 C CG  . HIS D 4 269 ? 103.740 111.537 67.608  1.00 75.89  ? 269 HIS R CG  1 
ATOM 6437 N ND1 . HIS D 4 269 ? 104.224 111.055 66.413  1.00 74.52  ? 269 HIS R ND1 1 
ATOM 6438 C CD2 . HIS D 4 269 ? 104.490 112.624 67.906  1.00 77.10  ? 269 HIS R CD2 1 
ATOM 6439 C CE1 . HIS D 4 269 ? 105.230 111.811 66.012  1.00 75.53  ? 269 HIS R CE1 1 
ATOM 6440 N NE2 . HIS D 4 269 ? 105.406 112.775 66.897  1.00 76.97  ? 269 HIS R NE2 1 
ATOM 6441 N N   . PHE D 4 270 ? 101.174 108.395 70.027  1.00 70.13  ? 270 PHE R N   1 
ATOM 6442 C CA  . PHE D 4 270 ? 100.223 107.950 71.034  1.00 71.87  ? 270 PHE R CA  1 
ATOM 6443 C C   . PHE D 4 270 ? 100.945 107.436 72.269  1.00 74.72  ? 270 PHE R C   1 
ATOM 6444 O O   . PHE D 4 270 ? 100.538 107.721 73.402  1.00 80.33  ? 270 PHE R O   1 
ATOM 6445 C CB  . PHE D 4 270 ? 99.306  106.876 70.459  1.00 70.24  ? 270 PHE R CB  1 
ATOM 6446 C CG  . PHE D 4 270 ? 98.190  106.490 71.375  1.00 71.28  ? 270 PHE R CG  1 
ATOM 6447 C CD1 . PHE D 4 270 ? 97.466  107.455 72.044  1.00 71.13  ? 270 PHE R CD1 1 
ATOM 6448 C CD2 . PHE D 4 270 ? 97.872  105.161 71.576  1.00 73.26  ? 270 PHE R CD2 1 
ATOM 6449 C CE1 . PHE D 4 270 ? 96.440  107.103 72.892  1.00 72.09  ? 270 PHE R CE1 1 
ATOM 6450 C CE2 . PHE D 4 270 ? 96.848  104.803 72.423  1.00 75.42  ? 270 PHE R CE2 1 
ATOM 6451 C CZ  . PHE D 4 270 ? 96.130  105.776 73.082  1.00 75.75  ? 270 PHE R CZ  1 
ATOM 6452 N N   . SER D 4 271 ? 102.029 106.684 72.070  1.00 65.49  ? 271 SER R N   1 
ATOM 6453 C CA  . SER D 4 271 ? 102.804 106.209 73.209  1.00 65.43  ? 271 SER R CA  1 
ATOM 6454 C C   . SER D 4 271 ? 103.409 107.372 73.986  1.00 69.44  ? 271 SER R C   1 
ATOM 6455 O O   . SER D 4 271 ? 103.388 107.385 75.227  1.00 73.78  ? 271 SER R O   1 
ATOM 6456 C CB  . SER D 4 271 ? 103.886 105.253 72.727  1.00 62.98  ? 271 SER R CB  1 
ATOM 6457 O OG  . SER D 4 271 ? 104.779 105.910 71.848  1.00 70.85  ? 271 SER R OG  1 
ATOM 6458 N N   . LEU D 4 272 ? 103.942 108.369 73.273  1.00 72.17  ? 272 LEU R N   1 
ATOM 6459 C CA  . LEU D 4 272 ? 104.509 109.528 73.955  1.00 69.36  ? 272 LEU R CA  1 
ATOM 6460 C C   . LEU D 4 272 ? 103.441 110.309 74.704  1.00 69.04  ? 272 LEU R C   1 
ATOM 6461 O O   . LEU D 4 272 ? 103.697 110.834 75.791  1.00 72.61  ? 272 LEU R O   1 
ATOM 6462 C CB  . LEU D 4 272 ? 105.222 110.434 72.959  1.00 71.32  ? 272 LEU R CB  1 
ATOM 6463 C CG  . LEU D 4 272 ? 105.898 111.640 73.608  1.00 73.34  ? 272 LEU R CG  1 
ATOM 6464 C CD1 . LEU D 4 272 ? 106.982 111.191 74.568  1.00 69.66  ? 272 LEU R CD1 1 
ATOM 6465 C CD2 . LEU D 4 272 ? 106.463 112.568 72.550  1.00 76.68  ? 272 LEU R CD2 1 
ATOM 6466 N N   . LEU D 4 273 ? 102.248 110.425 74.129  1.00 68.55  ? 273 LEU R N   1 
ATOM 6467 C CA  . LEU D 4 273 ? 101.171 111.123 74.817  1.00 67.93  ? 273 LEU R CA  1 
ATOM 6468 C C   . LEU D 4 273 ? 100.751 110.370 76.070  1.00 66.41  ? 273 LEU R C   1 
ATOM 6469 O O   . LEU D 4 273 ? 100.458 110.982 77.102  1.00 70.30  ? 273 LEU R O   1 
ATOM 6470 C CB  . LEU D 4 273 ? 99.998  111.323 73.858  1.00 67.45  ? 273 LEU R CB  1 
ATOM 6471 C CG  . LEU D 4 273 ? 98.802  112.174 74.263  1.00 71.22  ? 273 LEU R CG  1 
ATOM 6472 C CD1 . LEU D 4 273 ? 98.152  112.750 73.023  1.00 70.80  ? 273 LEU R CD1 1 
ATOM 6473 C CD2 . LEU D 4 273 ? 97.798  111.320 75.012  1.00 70.28  ? 273 LEU R CD2 1 
ATOM 6474 N N   . LEU D 4 274 ? 100.722 109.040 76.000  1.00 61.56  ? 274 LEU R N   1 
ATOM 6475 C CA  . LEU D 4 274 ? 100.332 108.255 77.164  1.00 60.35  ? 274 LEU R CA  1 
ATOM 6476 C C   . LEU D 4 274 ? 101.372 108.329 78.271  1.00 62.86  ? 274 LEU R C   1 
ATOM 6477 O O   . LEU D 4 274 ? 101.015 108.273 79.452  1.00 66.47  ? 274 LEU R O   1 
ATOM 6478 C CB  . LEU D 4 274 ? 100.092 106.802 76.761  1.00 62.71  ? 274 LEU R CB  1 
ATOM 6479 C CG  . LEU D 4 274 ? 99.612  105.875 77.870  1.00 67.39  ? 274 LEU R CG  1 
ATOM 6480 C CD1 . LEU D 4 274 ? 98.263  106.334 78.387  1.00 65.05  ? 274 LEU R CD1 1 
ATOM 6481 C CD2 . LEU D 4 274 ? 99.542  104.441 77.373  1.00 65.52  ? 274 LEU R CD2 1 
ATOM 6482 N N   . THR D 4 275 ? 102.658 108.454 77.922  1.00 68.53  ? 275 THR R N   1 
ATOM 6483 C CA  . THR D 4 275 ? 103.642 108.437 79.020  1.00 65.64  ? 275 THR R CA  1 
ATOM 6484 C C   . THR D 4 275 ? 103.593 109.682 79.902  1.00 63.28  ? 275 THR R C   1 
ATOM 6485 O O   . THR D 4 275 ? 104.457 109.798 80.773  1.00 66.09  ? 275 THR R O   1 
ATOM 6486 C CB  . THR D 4 275 ? 105.067 108.265 78.493  1.00 63.39  ? 275 THR R CB  1 
ATOM 6487 O OG1 . THR D 4 275 ? 105.957 108.079 79.599  1.00 65.92  ? 275 THR R OG1 1 
ATOM 6488 C CG2 . THR D 4 275 ? 105.511 109.493 77.754  1.00 62.23  ? 275 THR R CG2 1 
ATOM 6489 N N   . SER D 4 276 ? 102.650 110.605 79.731  1.00 57.11  ? 276 SER R N   1 
ATOM 6490 C CA  . SER D 4 276 ? 102.589 111.824 80.525  1.00 50.87  ? 276 SER R CA  1 
ATOM 6491 C C   . SER D 4 276 ? 101.734 111.687 81.774  1.00 51.77  ? 276 SER R C   1 
ATOM 6492 O O   . SER D 4 276 ? 101.595 112.662 82.516  1.00 57.33  ? 276 SER R O   1 
ATOM 6493 C CB  . SER D 4 276 ? 102.060 112.979 79.674  1.00 54.84  ? 276 SER R CB  1 
ATOM 6494 N N   . PHE D 4 277 ? 101.158 110.517 82.024  1.00 53.90  ? 277 PHE R N   1 
ATOM 6495 C CA  . PHE D 4 277 ? 100.294 110.333 83.180  1.00 59.46  ? 277 PHE R CA  1 
ATOM 6496 C C   . PHE D 4 277 ? 101.069 110.025 84.450  1.00 60.28  ? 277 PHE R C   1 
ATOM 6497 O O   . PHE D 4 277 ? 100.450 109.845 85.506  1.00 66.71  ? 277 PHE R O   1 
ATOM 6498 C CB  . PHE D 4 277 ? 99.283  109.220 82.912  1.00 61.38  ? 277 PHE R CB  1 
ATOM 6499 C CG  . PHE D 4 277 ? 98.128  109.649 82.065  1.00 56.20  ? 277 PHE R CG  1 
ATOM 6500 C CD1 . PHE D 4 277 ? 97.586  110.907 82.202  1.00 56.62  ? 277 PHE R CD1 1 
ATOM 6501 C CD2 . PHE D 4 277 ? 97.586  108.794 81.130  1.00 58.22  ? 277 PHE R CD2 1 
ATOM 6502 C CE1 . PHE D 4 277 ? 96.525  111.305 81.424  1.00 62.32  ? 277 PHE R CE1 1 
ATOM 6503 C CE2 . PHE D 4 277 ? 96.525  109.188 80.350  1.00 61.34  ? 277 PHE R CE2 1 
ATOM 6504 C CZ  . PHE D 4 277 ? 95.995  110.446 80.498  1.00 62.00  ? 277 PHE R CZ  1 
ATOM 6505 N N   . ASN D 4 278 ? 102.396 109.947 84.371  1.00 61.12  ? 278 ASN R N   1 
ATOM 6506 C CA  . ASN D 4 278 ? 103.193 109.714 85.568  1.00 66.28  ? 278 ASN R CA  1 
ATOM 6507 C C   . ASN D 4 278 ? 103.031 110.856 86.562  1.00 74.17  ? 278 ASN R C   1 
ATOM 6508 O O   . ASN D 4 278 ? 102.999 110.633 87.779  1.00 75.17  ? 278 ASN R O   1 
ATOM 6509 C CB  . ASN D 4 278 ? 104.660 109.534 85.190  1.00 63.44  ? 278 ASN R CB  1 
ATOM 6510 C CG  . ASN D 4 278 ? 105.468 108.910 86.297  1.00 70.00  ? 278 ASN R CG  1 
ATOM 6511 O OD1 . ASN D 4 278 ? 104.937 108.176 87.126  1.00 68.77  ? 278 ASN R OD1 1 
ATOM 6512 N ND2 . ASN D 4 278 ? 106.761 109.200 86.321  1.00 72.23  ? 278 ASN R ND2 1 
ATOM 6513 N N   . CYS D 4 279 ? 102.921 112.088 86.059  1.00 69.90  ? 279 CYS R N   1 
ATOM 6514 C CA  . CYS D 4 279 ? 102.766 113.245 86.930  1.00 65.58  ? 279 CYS R CA  1 
ATOM 6515 C C   . CYS D 4 279 ? 101.463 113.217 87.715  1.00 68.22  ? 279 CYS R C   1 
ATOM 6516 O O   . CYS D 4 279 ? 101.370 113.866 88.762  1.00 74.37  ? 279 CYS R O   1 
ATOM 6517 C CB  . CYS D 4 279 ? 102.860 114.526 86.110  1.00 64.68  ? 279 CYS R CB  1 
ATOM 6518 S SG  . CYS D 4 279 ? 104.485 114.785 85.388  1.00 84.23  ? 279 CYS R SG  1 
ATOM 6519 N N   . VAL D 4 280 ? 100.460 112.488 87.242  1.00 54.83  ? 280 VAL R N   1 
ATOM 6520 C CA  . VAL D 4 280 ? 99.223  112.334 87.995  1.00 51.90  ? 280 VAL R CA  1 
ATOM 6521 C C   . VAL D 4 280 ? 99.263  111.083 88.860  1.00 62.71  ? 280 VAL R C   1 
ATOM 6522 O O   . VAL D 4 280 ? 98.722  111.067 89.968  1.00 66.76  ? 280 VAL R O   1 
ATOM 6523 C CB  . VAL D 4 280 ? 98.027  112.319 87.026  1.00 55.16  ? 280 VAL R CB  1 
ATOM 6524 C CG1 . VAL D 4 280 ? 96.737  112.029 87.763  1.00 59.72  ? 280 VAL R CG1 1 
ATOM 6525 C CG2 . VAL D 4 280 ? 97.935  113.634 86.286  1.00 61.68  ? 280 VAL R CG2 1 
ATOM 6526 N N   . ALA D 4 281 ? 99.920  110.027 88.377  1.00 63.33  ? 281 ALA R N   1 
ATOM 6527 C CA  . ALA D 4 281 ? 99.942  108.766 89.109  1.00 56.62  ? 281 ALA R CA  1 
ATOM 6528 C C   . ALA D 4 281 ? 100.814 108.842 90.356  1.00 54.85  ? 281 ALA R C   1 
ATOM 6529 O O   . ALA D 4 281 ? 100.442 108.310 91.408  1.00 65.43  ? 281 ALA R O   1 
ATOM 6530 C CB  . ALA D 4 281 ? 100.423 107.643 88.196  1.00 57.09  ? 281 ALA R CB  1 
ATOM 6531 N N   . ASP D 4 282 ? 101.976 109.488 90.264  1.00 50.31  ? 282 ASP R N   1 
ATOM 6532 C CA  . ASP D 4 282 ? 102.940 109.437 91.363  1.00 57.54  ? 282 ASP R CA  1 
ATOM 6533 C C   . ASP D 4 282 ? 102.421 110.043 92.662  1.00 61.01  ? 282 ASP R C   1 
ATOM 6534 O O   . ASP D 4 282 ? 102.525 109.376 93.708  1.00 67.55  ? 282 ASP R O   1 
ATOM 6535 C CB  . ASP D 4 282 ? 104.251 110.097 90.929  1.00 62.74  ? 282 ASP R CB  1 
ATOM 6536 C CG  . ASP D 4 282 ? 105.102 109.187 90.069  1.00 71.79  ? 282 ASP R CG  1 
ATOM 6537 O OD1 . ASP D 4 282 ? 104.883 107.958 90.104  1.00 73.11  ? 282 ASP R OD1 1 
ATOM 6538 O OD2 . ASP D 4 282 ? 105.990 109.700 89.358  1.00 72.73  ? 282 ASP R OD2 1 
ATOM 6539 N N   . PRO D 4 283 ? 101.878 111.266 92.692  1.00 54.62  ? 283 PRO R N   1 
ATOM 6540 C CA  . PRO D 4 283 ? 101.369 111.790 93.968  1.00 54.46  ? 283 PRO R CA  1 
ATOM 6541 C C   . PRO D 4 283 ? 100.249 110.960 94.564  1.00 58.62  ? 283 PRO R C   1 
ATOM 6542 O O   . PRO D 4 283 ? 100.135 110.882 95.793  1.00 63.57  ? 283 PRO R O   1 
ATOM 6543 C CB  . PRO D 4 283 ? 100.890 113.200 93.600  1.00 54.39  ? 283 PRO R CB  1 
ATOM 6544 C CG  . PRO D 4 283 ? 100.647 113.151 92.155  1.00 57.46  ? 283 PRO R CG  1 
ATOM 6545 C CD  . PRO D 4 283 ? 101.695 112.245 91.609  1.00 58.10  ? 283 PRO R CD  1 
ATOM 6546 N N   . VAL D 4 284 ? 99.413  110.341 93.733  1.00 53.38  ? 284 VAL R N   1 
ATOM 6547 C CA  . VAL D 4 284 ? 98.320  109.528 94.250  1.00 47.55  ? 284 VAL R CA  1 
ATOM 6548 C C   . VAL D 4 284 ? 98.859  108.282 94.938  1.00 58.63  ? 284 VAL R C   1 
ATOM 6549 O O   . VAL D 4 284 ? 98.455  107.948 96.057  1.00 65.48  ? 284 VAL R O   1 
ATOM 6550 C CB  . VAL D 4 284 ? 97.342  109.169 93.119  1.00 50.50  ? 284 VAL R CB  1 
ATOM 6551 C CG1 . VAL D 4 284 ? 96.264  108.235 93.622  1.00 55.02  ? 284 VAL R CG1 1 
ATOM 6552 C CG2 . VAL D 4 284 ? 96.725  110.427 92.544  1.00 56.58  ? 284 VAL R CG2 1 
ATOM 6553 N N   . LEU D 4 285 ? 99.779  107.577 94.285  1.00 57.62  ? 285 LEU R N   1 
ATOM 6554 C CA  . LEU D 4 285 ? 100.251 106.302 94.808  1.00 51.07  ? 285 LEU R CA  1 
ATOM 6555 C C   . LEU D 4 285 ? 101.324 106.447 95.874  1.00 52.86  ? 285 LEU R C   1 
ATOM 6556 O O   . LEU D 4 285 ? 101.584 105.482 96.597  1.00 54.20  ? 285 LEU R O   1 
ATOM 6557 C CB  . LEU D 4 285 ? 100.792 105.434 93.677  1.00 48.41  ? 285 LEU R CB  1 
ATOM 6558 C CG  . LEU D 4 285 ? 99.755  104.570 92.978  1.00 54.86  ? 285 LEU R CG  1 
ATOM 6559 C CD1 . LEU D 4 285 ? 100.423 103.773 91.895  1.00 55.91  ? 285 LEU R CD1 1 
ATOM 6560 C CD2 . LEU D 4 285 ? 99.052  103.656 93.966  1.00 55.68  ? 285 LEU R CD2 1 
ATOM 6561 N N   . TYR D 4 286 ? 101.958 107.611 95.988  1.00 55.25  ? 286 TYR R N   1 
ATOM 6562 C CA  . TYR D 4 286 ? 103.044 107.779 96.936  1.00 54.69  ? 286 TYR R CA  1 
ATOM 6563 C C   . TYR D 4 286 ? 102.780 108.821 98.009  1.00 59.01  ? 286 TYR R C   1 
ATOM 6564 O O   . TYR D 4 286 ? 103.590 108.938 98.935  1.00 64.58  ? 286 TYR R O   1 
ATOM 6565 C CB  . TYR D 4 286 ? 104.341 108.148 96.200  1.00 58.26  ? 286 TYR R CB  1 
ATOM 6566 C CG  . TYR D 4 286 ? 104.937 107.012 95.407  1.00 58.92  ? 286 TYR R CG  1 
ATOM 6567 C CD1 . TYR D 4 286 ? 104.550 106.778 94.102  1.00 58.93  ? 286 TYR R CD1 1 
ATOM 6568 C CD2 . TYR D 4 286 ? 105.883 106.174 95.964  1.00 60.15  ? 286 TYR R CD2 1 
ATOM 6569 C CE1 . TYR D 4 286 ? 105.083 105.745 93.377  1.00 55.00  ? 286 TYR R CE1 1 
ATOM 6570 C CE2 . TYR D 4 286 ? 106.425 105.138 95.245  1.00 58.67  ? 286 TYR R CE2 1 
ATOM 6571 C CZ  . TYR D 4 286 ? 106.020 104.928 93.951  1.00 58.96  ? 286 TYR R CZ  1 
ATOM 6572 O OH  . TYR D 4 286 ? 106.560 103.893 93.229  1.00 61.02  ? 286 TYR R OH  1 
ATOM 6573 N N   . CYS D 4 287 ? 101.691 109.580 97.922  1.00 60.80  ? 287 CYS R N   1 
ATOM 6574 C CA  . CYS D 4 287 ? 101.429 110.621 98.907  1.00 61.52  ? 287 CYS R CA  1 
ATOM 6575 C C   . CYS D 4 287 ? 99.995  110.690 99.399  1.00 60.91  ? 287 CYS R C   1 
ATOM 6576 O O   . CYS D 4 287 ? 99.738  111.446 100.338 1.00 64.74  ? 287 CYS R O   1 
ATOM 6577 C CB  . CYS D 4 287 ? 101.815 111.996 98.345  1.00 59.46  ? 287 CYS R CB  1 
ATOM 6578 N N   . PHE D 4 288 ? 99.055  109.957 98.812  1.00 59.40  ? 288 PHE R N   1 
ATOM 6579 C CA  . PHE D 4 288 ? 97.649  110.051 99.186  1.00 55.41  ? 288 PHE R CA  1 
ATOM 6580 C C   . PHE D 4 288 ? 97.097  108.779 99.801  1.00 63.95  ? 288 PHE R C   1 
ATOM 6581 O O   . PHE D 4 288 ? 96.353  108.849 100.780 1.00 70.36  ? 288 PHE R O   1 
ATOM 6582 C CB  . PHE D 4 288 ? 96.800  110.418 97.968  1.00 50.24  ? 288 PHE R CB  1 
ATOM 6583 C CG  . PHE D 4 288 ? 96.850  111.869 97.610  1.00 54.81  ? 288 PHE R CG  1 
ATOM 6584 C CD1 . PHE D 4 288 ? 97.660  112.740 98.303  1.00 55.28  ? 288 PHE R CD1 1 
ATOM 6585 C CD2 . PHE D 4 288 ? 96.088  112.360 96.572  1.00 62.14  ? 288 PHE R CD2 1 
ATOM 6586 C CE1 . PHE D 4 288 ? 97.707  114.072 97.969  1.00 61.79  ? 288 PHE R CE1 1 
ATOM 6587 C CE2 . PHE D 4 288 ? 96.132  113.690 96.235  1.00 61.73  ? 288 PHE R CE2 1 
ATOM 6588 C CZ  . PHE D 4 288 ? 96.943  114.545 96.933  1.00 62.69  ? 288 PHE R CZ  1 
ATOM 6589 N N   . VAL D 4 289 ? 97.436  107.616 99.257  1.00 60.75  ? 289 VAL R N   1 
ATOM 6590 C CA  . VAL D 4 289 ? 96.943  106.344 99.802  1.00 56.77  ? 289 VAL R CA  1 
ATOM 6591 C C   . VAL D 4 289 ? 97.916  105.951 100.908 1.00 60.74  ? 289 VAL R C   1 
ATOM 6592 O O   . VAL D 4 289 ? 98.827  105.136 100.745 1.00 61.85  ? 289 VAL R O   1 
ATOM 6593 C CB  . VAL D 4 289 ? 96.767  105.276 98.715  1.00 55.68  ? 289 VAL R CB  1 
ATOM 6594 C CG1 . VAL D 4 289 ? 95.719  105.733 97.729  1.00 58.16  ? 289 VAL R CG1 1 
ATOM 6595 C CG2 . VAL D 4 289 ? 98.056  105.055 97.945  1.00 58.22  ? 289 VAL R CG2 1 
ATOM 6596 N N   . SER D 4 290 ? 97.700  106.541 102.079 1.00 69.06  ? 290 SER R N   1 
ATOM 6597 C CA  . SER D 4 290 ? 98.530  106.309 103.250 1.00 68.33  ? 290 SER R CA  1 
ATOM 6598 C C   . SER D 4 290 ? 97.794  106.858 104.459 1.00 72.27  ? 290 SER R C   1 
ATOM 6599 O O   . SER D 4 290 ? 97.208  107.941 104.389 1.00 77.15  ? 290 SER R O   1 
ATOM 6600 C CB  . SER D 4 290 ? 99.901  106.977 103.110 1.00 68.73  ? 290 SER R CB  1 
ATOM 6601 N N   . GLU D 4 291 ? 97.817  106.106 105.560 1.00 80.45  ? 291 GLU R N   1 
ATOM 6602 C CA  . GLU D 4 291 ? 97.136  106.564 106.764 1.00 80.08  ? 291 GLU R CA  1 
ATOM 6603 C C   . GLU D 4 291 ? 97.739  107.862 107.280 1.00 83.31  ? 291 GLU R C   1 
ATOM 6604 O O   . GLU D 4 291 ? 97.028  108.693 107.859 1.00 87.50  ? 291 GLU R O   1 
ATOM 6605 C CB  . GLU D 4 291 ? 97.188  105.485 107.844 1.00 81.83  ? 291 GLU R CB  1 
ATOM 6606 N N   . THR D 4 292 ? 99.042  108.059 107.070 1.00 77.37  ? 292 THR R N   1 
ATOM 6607 C CA  . THR D 4 292 ? 99.675  109.305 107.482 1.00 77.47  ? 292 THR R CA  1 
ATOM 6608 C C   . THR D 4 292 ? 99.103  110.495 106.720 1.00 77.05  ? 292 THR R C   1 
ATOM 6609 O O   . THR D 4 292 ? 98.899  111.569 107.298 1.00 78.21  ? 292 THR R O   1 
ATOM 6610 C CB  . THR D 4 292 ? 101.194 109.209 107.310 1.00 77.68  ? 292 THR R CB  1 
ATOM 6611 O OG1 . THR D 4 292 ? 101.818 110.374 107.866 1.00 79.34  ? 292 THR R OG1 1 
ATOM 6612 C CG2 . THR D 4 292 ? 101.592 109.050 105.849 1.00 77.00  ? 292 THR R CG2 1 
ATOM 6613 N N   . THR D 4 293 ? 98.826  110.325 105.427 1.00 71.95  ? 293 THR R N   1 
ATOM 6614 C CA  . THR D 4 293 ? 98.255  111.420 104.654 1.00 69.57  ? 293 THR R CA  1 
ATOM 6615 C C   . THR D 4 293 ? 96.812  111.689 105.052 1.00 72.63  ? 293 THR R C   1 
ATOM 6616 O O   . THR D 4 293 ? 96.365  112.841 105.013 1.00 76.02  ? 293 THR R O   1 
ATOM 6617 C CB  . THR D 4 293 ? 98.342  111.117 103.162 1.00 66.22  ? 293 THR R CB  1 
ATOM 6618 N N   . HIS D 4 294 ? 96.073  110.650 105.434 1.00 70.54  ? 294 HIS R N   1 
ATOM 6619 C CA  . HIS D 4 294 ? 94.708  110.824 105.907 1.00 70.64  ? 294 HIS R CA  1 
ATOM 6620 C C   . HIS D 4 294 ? 94.644  111.349 107.332 1.00 74.69  ? 294 HIS R C   1 
ATOM 6621 O O   . HIS D 4 294 ? 93.573  111.785 107.765 1.00 75.09  ? 294 HIS R O   1 
ATOM 6622 C CB  . HIS D 4 294 ? 93.949  109.501 105.826 1.00 74.49  ? 294 HIS R CB  1 
ATOM 6623 C CG  . HIS D 4 294 ? 93.745  109.004 104.431 1.00 76.30  ? 294 HIS R CG  1 
ATOM 6624 N ND1 . HIS D 4 294 ? 93.218  107.762 104.157 1.00 78.73  ? 294 HIS R ND1 1 
ATOM 6625 C CD2 . HIS D 4 294 ? 93.992  109.581 103.233 1.00 75.91  ? 294 HIS R CD2 1 
ATOM 6626 C CE1 . HIS D 4 294 ? 93.151  107.593 102.849 1.00 76.65  ? 294 HIS R CE1 1 
ATOM 6627 N NE2 . HIS D 4 294 ? 93.614  108.683 102.265 1.00 77.52  ? 294 HIS R NE2 1 
ATOM 6628 N N   . ARG D 4 295 ? 95.750  111.314 108.066 1.00 84.44  ? 295 ARG R N   1 
ATOM 6629 C CA  . ARG D 4 295 ? 95.786  111.819 109.430 1.00 87.28  ? 295 ARG R CA  1 
ATOM 6630 C C   . ARG D 4 295 ? 96.154  113.295 109.508 1.00 87.90  ? 295 ARG R C   1 
ATOM 6631 O O   . ARG D 4 295 ? 96.258  113.834 110.615 1.00 89.15  ? 295 ARG R O   1 
ATOM 6632 C CB  . ARG D 4 295 ? 96.771  111.000 110.270 1.00 84.25  ? 295 ARG R CB  1 
ATOM 6633 N N   . ASP D 4 296 ? 96.353  113.957 108.372 1.00 81.47  ? 296 ASP R N   1 
ATOM 6634 C CA  . ASP D 4 296 ? 96.714  115.369 108.317 1.00 80.14  ? 296 ASP R CA  1 
ATOM 6635 C C   . ASP D 4 296 ? 95.872  116.089 107.275 1.00 79.83  ? 296 ASP R C   1 
ATOM 6636 O O   . ASP D 4 296 ? 96.373  116.847 106.444 1.00 83.69  ? 296 ASP R O   1 
ATOM 6637 C CB  . ASP D 4 296 ? 98.200  115.536 108.021 1.00 79.78  ? 296 ASP R CB  1 
ATOM 6638 N N   . LEU D 4 297 ? 94.567  115.841 107.323 1.00 78.86  ? 297 LEU R N   1 
ATOM 6639 C CA  . LEU D 4 297 ? 93.635  116.457 106.387 1.00 83.54  ? 297 LEU R CA  1 
ATOM 6640 C C   . LEU D 4 297 ? 92.214  116.443 106.941 1.00 88.70  ? 297 LEU R C   1 
ATOM 6641 O O   . LEU D 4 297 ? 92.004  116.625 108.141 1.00 85.80  ? 297 LEU R O   1 
ATOM 6642 C CB  . LEU D 4 297 ? 93.682  115.741 105.035 1.00 84.66  ? 297 LEU R CB  1 
ATOM 6643 C CG  . LEU D 4 297 ? 92.817  116.319 103.912 1.00 83.71  ? 297 LEU R CG  1 
ATOM 6644 C CD1 . LEU D 4 297 ? 93.143  115.652 102.585 1.00 84.87  ? 297 LEU R CD1 1 
ATOM 6645 C CD2 . LEU D 4 297 ? 91.337  116.183 104.237 1.00 80.44  ? 297 LEU R CD2 1 
# 
