data_8Z4E
# 
_entry.id   8Z4E 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.399 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8Z4E         pdb_00008z4e 10.2210/pdb8z4e/pdb 
WWPDB D_1300046940 ?            ?                   
EMDB  EMD-39762    ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-01-22 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8Z4E 
_pdbx_database_status.recvd_initial_deposition_date   2024-04-17 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBC 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        
'Structure of human 18_14D scFv and 1G01 scFv in complex with influenza virus neuraminidase from A/Yunan/DQ001/2016 (H5N6)' 
_pdbx_database_related.db_id          EMD-39762 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 3 
_pdbx_contact_author.email              shiyi@im.ac.cn 
_pdbx_contact_author.name_first         Yi 
_pdbx_contact_author.name_last          Shi 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-3053-2687 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Wang, M.' 1 ? 
'Peng, Q.' 2 ? 
'Gao, Y.'  3 ? 
'Shi, Y.'  4 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Nat Commun' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2041-1723 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            15 
_citation.language                  ? 
_citation.page_first                8871 
_citation.page_last                 8871 
_citation.title                     
;A human monoclonal antibody targeting the monomeric N6 neuraminidase confers protection against avian H5N6 influenza virus infection.
;
_citation.year                      2024 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1038/s41467-024-53301-6 
_citation.pdbx_database_id_PubMed   39402031 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Wang, M.'   1  ?                   
primary 'Gao, Y.'    2  ?                   
primary 'Shen, C.'   3  0000-0001-8607-3750 
primary 'Yang, W.'   4  ?                   
primary 'Peng, Q.'   5  ?                   
primary 'Cheng, J.'  6  ?                   
primary 'Shen, H.M.' 7  0000-0001-7369-5227 
primary 'Yang, Y.'   8  0000-0002-6489-4459 
primary 'Gao, G.F.'  9  0000-0002-3869-615X 
primary 'Shi, Y.'    10 0000-0002-3053-2687 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man Neuraminidase                                                                             42155.621 1 3.2.1.18 ? 
? 
;Sequence reference for Influenza A virus (A/Yunan/DQ001/2016 (H5N6)) is not available at the time of biocuration. Current sequence reference is from UniProt ID A0A0K0YAP8.
;
2 polymer     man 'Light chain of 18_14D scFv'                                                              22813.119 1 ?        ? 
? 
;According to author, Entity 2 (Light chain of 18_14D scFV, 216 aa, chain B) and Entity 3 (Heavy chain of 18_14D scFV, 236 aa, chain C) are not expressed as one chain.
;
3 polymer     man 'Heavy chain of 18_14D scFv'                                                              25064.055 1 ?        ? 
? ? 
4 polymer     man 'Heavy chain of 1G01 scFv'                                                                24933.908 1 ?        ? 
? 
;According to author, Entity 4 (Heavy chain of 1G01 scFv, 232 aa, chain E) and Entity 5 (Light chain of 1G01 scFV, 216 aa, chain F) are not expressed as one chain.
;
5 polymer     man 'Light chain of 1G01 scFv'                                                                23677.273 1 ?        ? 
? ? 
6 branched    man '2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose' 424.401   1 ?        ? 
? ? 
7 non-polymer syn 'CALCIUM ION'                                                                             40.078    1 ?        ? 
? ? 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;RTFLNLTKPLCEVNSWHILSKDNAIRIGEDAHILVTREPYLSCDPQGCRMFALSQGTTLRGRHANGTIHDKSPFRALISW
EMGQAPSPYNTRVECIGWSSTSCHDGISRMSICISGPNNNASAVVWYRGRPVTEIPSWVGNILRTQESECVCHKGICPVV
MTDGPANNKAATKIIYFKEGKIQKIEELQGNAQHIEECSCYGAAGMIKCVCRDNWKGANRPIITIDPEMMTHTSKYLCSK
ILTDTSRPNDPTNGNCDEPITGGSPDPGVKGFAFLDGENSWLGRTISKDSRSGYEMLKVPNAETDTQSGPTSYQLIVNNQ
NWSGYSGAFIDYWANKECFNPCFYVELIRGRPKEIDVLWASNSMVALCGSRERLGSWSW
;
;RTFLNLTKPLCEVNSWHILSKDNAIRIGEDAHILVTREPYLSCDPQGCRMFALSQGTTLRGRHANGTIHDKSPFRALISW
EMGQAPSPYNTRVECIGWSSTSCHDGISRMSICISGPNNNASAVVWYRGRPVTEIPSWVGNILRTQESECVCHKGICPVV
MTDGPANNKAATKIIYFKEGKIQKIEELQGNAQHIEECSCYGAAGMIKCVCRDNWKGANRPIITIDPEMMTHTSKYLCSK
ILTDTSRPNDPTNGNCDEPITGGSPDPGVKGFAFLDGENSWLGRTISKDSRSGYEMLKVPNAETDTQSGPTSYQLIVNNQ
NWSGYSGAFIDYWANKECFNPCFYVELIRGRPKEIDVLWASNSMVALCGSRERLGSWSW
;
A ? 
2 'polypeptide(L)' no no 
;QSVLTQPASVSGSPGQSITISCTGTSSDVGGYNYVSWYQQHPGKAPKLMIYDVSKRPSGVSNRFSGSKSGNTASLTISGL
QAEDEADYYCSSYTSSSTWVFGGGTKLTVLGQPKAAPSVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADSSPVK
AGVETTTPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEGSTVEKTVAPTECS
;
;QSVLTQPASVSGSPGQSITISCTGTSSDVGGYNYVSWYQQHPGKAPKLMIYDVSKRPSGVSNRFSGSKSGNTASLTISGL
QAEDEADYYCSSYTSSSTWVFGGGTKLTVLGQPKAAPSVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADSSPVK
AGVETTTPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEGSTVEKTVAPTECS
;
B ? 
3 'polypeptide(L)' no no 
;QVQLVQSGAEVKKPGSSVKVSCKASGGTFSSYAISWVRQAPGQGLEWMGGIIPIFGTANYAQKFQGRVTITADESTSTAY
MELSSLRSEDTAVYYCARGQLRYFDWPTIPSSYYGMDVWGQGTTVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKD
YFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKSCDKTH
;
;QVQLVQSGAEVKKPGSSVKVSCKASGGTFSSYAISWVRQAPGQGLEWMGGIIPIFGTANYAQKFQGRVTITADESTSTAY
MELSSLRSEDTAVYYCARGQLRYFDWPTIPSSYYGMDVWGQGTTVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKD
YFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKSCDKTH
;
C ? 
4 'polypeptide(L)' no no 
;EVQLVESGGRALRPGGSLRLSCAASGFKFDDYAMSWVRQVPGKGLEFVSGLNWNGDITAYTDSVKGRFTVSRDNAKNSLY
LHINSPKPEDTALYYCARTSSWGDYTRGPEPKITWYFDLWGRGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVK
DYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKS
;
;EVQLVESGGRALRPGGSLRLSCAASGFKFDDYAMSWVRQVPGKGLEFVSGLNWNGDITAYTDSVKGRFTVSRDNAKNSLY
LHINSPKPEDTALYYCARTSSWGDYTRGPEPKITWYFDLWGRGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVK
DYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKS
;
E ? 
5 'polypeptide(L)' no no 
;DDIQLTQSPSFLSASVGDRITITCRASQGIDGYLAWYQQRPGKAPNLLIYAASLLQSGVPSRFSGSGYGTEFTLTISSLQ
PEDFATYYCQHLDSYPLFTFGPGTKVDIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGN
SQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
;
;DDIQLTQSPSFLSASVGDRITITCRASQGIDGYLAWYQQRPGKAPNLLIYAASLLQSGVPSRFSGSGYGTEFTLTISSLQ
PEDFATYYCQHLDSYPLFTFGPGTKVDIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGN
SQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
;
F ? 
# 
_pdbx_entity_nonpoly.entity_id   7 
_pdbx_entity_nonpoly.name        'CALCIUM ION' 
_pdbx_entity_nonpoly.comp_id     CA 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   ARG n 
1 2   THR n 
1 3   PHE n 
1 4   LEU n 
1 5   ASN n 
1 6   LEU n 
1 7   THR n 
1 8   LYS n 
1 9   PRO n 
1 10  LEU n 
1 11  CYS n 
1 12  GLU n 
1 13  VAL n 
1 14  ASN n 
1 15  SER n 
1 16  TRP n 
1 17  HIS n 
1 18  ILE n 
1 19  LEU n 
1 20  SER n 
1 21  LYS n 
1 22  ASP n 
1 23  ASN n 
1 24  ALA n 
1 25  ILE n 
1 26  ARG n 
1 27  ILE n 
1 28  GLY n 
1 29  GLU n 
1 30  ASP n 
1 31  ALA n 
1 32  HIS n 
1 33  ILE n 
1 34  LEU n 
1 35  VAL n 
1 36  THR n 
1 37  ARG n 
1 38  GLU n 
1 39  PRO n 
1 40  TYR n 
1 41  LEU n 
1 42  SER n 
1 43  CYS n 
1 44  ASP n 
1 45  PRO n 
1 46  GLN n 
1 47  GLY n 
1 48  CYS n 
1 49  ARG n 
1 50  MET n 
1 51  PHE n 
1 52  ALA n 
1 53  LEU n 
1 54  SER n 
1 55  GLN n 
1 56  GLY n 
1 57  THR n 
1 58  THR n 
1 59  LEU n 
1 60  ARG n 
1 61  GLY n 
1 62  ARG n 
1 63  HIS n 
1 64  ALA n 
1 65  ASN n 
1 66  GLY n 
1 67  THR n 
1 68  ILE n 
1 69  HIS n 
1 70  ASP n 
1 71  LYS n 
1 72  SER n 
1 73  PRO n 
1 74  PHE n 
1 75  ARG n 
1 76  ALA n 
1 77  LEU n 
1 78  ILE n 
1 79  SER n 
1 80  TRP n 
1 81  GLU n 
1 82  MET n 
1 83  GLY n 
1 84  GLN n 
1 85  ALA n 
1 86  PRO n 
1 87  SER n 
1 88  PRO n 
1 89  TYR n 
1 90  ASN n 
1 91  THR n 
1 92  ARG n 
1 93  VAL n 
1 94  GLU n 
1 95  CYS n 
1 96  ILE n 
1 97  GLY n 
1 98  TRP n 
1 99  SER n 
1 100 SER n 
1 101 THR n 
1 102 SER n 
1 103 CYS n 
1 104 HIS n 
1 105 ASP n 
1 106 GLY n 
1 107 ILE n 
1 108 SER n 
1 109 ARG n 
1 110 MET n 
1 111 SER n 
1 112 ILE n 
1 113 CYS n 
1 114 ILE n 
1 115 SER n 
1 116 GLY n 
1 117 PRO n 
1 118 ASN n 
1 119 ASN n 
1 120 ASN n 
1 121 ALA n 
1 122 SER n 
1 123 ALA n 
1 124 VAL n 
1 125 VAL n 
1 126 TRP n 
1 127 TYR n 
1 128 ARG n 
1 129 GLY n 
1 130 ARG n 
1 131 PRO n 
1 132 VAL n 
1 133 THR n 
1 134 GLU n 
1 135 ILE n 
1 136 PRO n 
1 137 SER n 
1 138 TRP n 
1 139 VAL n 
1 140 GLY n 
1 141 ASN n 
1 142 ILE n 
1 143 LEU n 
1 144 ARG n 
1 145 THR n 
1 146 GLN n 
1 147 GLU n 
1 148 SER n 
1 149 GLU n 
1 150 CYS n 
1 151 VAL n 
1 152 CYS n 
1 153 HIS n 
1 154 LYS n 
1 155 GLY n 
1 156 ILE n 
1 157 CYS n 
1 158 PRO n 
1 159 VAL n 
1 160 VAL n 
1 161 MET n 
1 162 THR n 
1 163 ASP n 
1 164 GLY n 
1 165 PRO n 
1 166 ALA n 
1 167 ASN n 
1 168 ASN n 
1 169 LYS n 
1 170 ALA n 
1 171 ALA n 
1 172 THR n 
1 173 LYS n 
1 174 ILE n 
1 175 ILE n 
1 176 TYR n 
1 177 PHE n 
1 178 LYS n 
1 179 GLU n 
1 180 GLY n 
1 181 LYS n 
1 182 ILE n 
1 183 GLN n 
1 184 LYS n 
1 185 ILE n 
1 186 GLU n 
1 187 GLU n 
1 188 LEU n 
1 189 GLN n 
1 190 GLY n 
1 191 ASN n 
1 192 ALA n 
1 193 GLN n 
1 194 HIS n 
1 195 ILE n 
1 196 GLU n 
1 197 GLU n 
1 198 CYS n 
1 199 SER n 
1 200 CYS n 
1 201 TYR n 
1 202 GLY n 
1 203 ALA n 
1 204 ALA n 
1 205 GLY n 
1 206 MET n 
1 207 ILE n 
1 208 LYS n 
1 209 CYS n 
1 210 VAL n 
1 211 CYS n 
1 212 ARG n 
1 213 ASP n 
1 214 ASN n 
1 215 TRP n 
1 216 LYS n 
1 217 GLY n 
1 218 ALA n 
1 219 ASN n 
1 220 ARG n 
1 221 PRO n 
1 222 ILE n 
1 223 ILE n 
1 224 THR n 
1 225 ILE n 
1 226 ASP n 
1 227 PRO n 
1 228 GLU n 
1 229 MET n 
1 230 MET n 
1 231 THR n 
1 232 HIS n 
1 233 THR n 
1 234 SER n 
1 235 LYS n 
1 236 TYR n 
1 237 LEU n 
1 238 CYS n 
1 239 SER n 
1 240 LYS n 
1 241 ILE n 
1 242 LEU n 
1 243 THR n 
1 244 ASP n 
1 245 THR n 
1 246 SER n 
1 247 ARG n 
1 248 PRO n 
1 249 ASN n 
1 250 ASP n 
1 251 PRO n 
1 252 THR n 
1 253 ASN n 
1 254 GLY n 
1 255 ASN n 
1 256 CYS n 
1 257 ASP n 
1 258 GLU n 
1 259 PRO n 
1 260 ILE n 
1 261 THR n 
1 262 GLY n 
1 263 GLY n 
1 264 SER n 
1 265 PRO n 
1 266 ASP n 
1 267 PRO n 
1 268 GLY n 
1 269 VAL n 
1 270 LYS n 
1 271 GLY n 
1 272 PHE n 
1 273 ALA n 
1 274 PHE n 
1 275 LEU n 
1 276 ASP n 
1 277 GLY n 
1 278 GLU n 
1 279 ASN n 
1 280 SER n 
1 281 TRP n 
1 282 LEU n 
1 283 GLY n 
1 284 ARG n 
1 285 THR n 
1 286 ILE n 
1 287 SER n 
1 288 LYS n 
1 289 ASP n 
1 290 SER n 
1 291 ARG n 
1 292 SER n 
1 293 GLY n 
1 294 TYR n 
1 295 GLU n 
1 296 MET n 
1 297 LEU n 
1 298 LYS n 
1 299 VAL n 
1 300 PRO n 
1 301 ASN n 
1 302 ALA n 
1 303 GLU n 
1 304 THR n 
1 305 ASP n 
1 306 THR n 
1 307 GLN n 
1 308 SER n 
1 309 GLY n 
1 310 PRO n 
1 311 THR n 
1 312 SER n 
1 313 TYR n 
1 314 GLN n 
1 315 LEU n 
1 316 ILE n 
1 317 VAL n 
1 318 ASN n 
1 319 ASN n 
1 320 GLN n 
1 321 ASN n 
1 322 TRP n 
1 323 SER n 
1 324 GLY n 
1 325 TYR n 
1 326 SER n 
1 327 GLY n 
1 328 ALA n 
1 329 PHE n 
1 330 ILE n 
1 331 ASP n 
1 332 TYR n 
1 333 TRP n 
1 334 ALA n 
1 335 ASN n 
1 336 LYS n 
1 337 GLU n 
1 338 CYS n 
1 339 PHE n 
1 340 ASN n 
1 341 PRO n 
1 342 CYS n 
1 343 PHE n 
1 344 TYR n 
1 345 VAL n 
1 346 GLU n 
1 347 LEU n 
1 348 ILE n 
1 349 ARG n 
1 350 GLY n 
1 351 ARG n 
1 352 PRO n 
1 353 LYS n 
1 354 GLU n 
1 355 ILE n 
1 356 ASP n 
1 357 VAL n 
1 358 LEU n 
1 359 TRP n 
1 360 ALA n 
1 361 SER n 
1 362 ASN n 
1 363 SER n 
1 364 MET n 
1 365 VAL n 
1 366 ALA n 
1 367 LEU n 
1 368 CYS n 
1 369 GLY n 
1 370 SER n 
1 371 ARG n 
1 372 GLU n 
1 373 ARG n 
1 374 LEU n 
1 375 GLY n 
1 376 SER n 
1 377 TRP n 
1 378 SER n 
1 379 TRP n 
2 1   GLN n 
2 2   SER n 
2 3   VAL n 
2 4   LEU n 
2 5   THR n 
2 6   GLN n 
2 7   PRO n 
2 8   ALA n 
2 9   SER n 
2 10  VAL n 
2 11  SER n 
2 12  GLY n 
2 13  SER n 
2 14  PRO n 
2 15  GLY n 
2 16  GLN n 
2 17  SER n 
2 18  ILE n 
2 19  THR n 
2 20  ILE n 
2 21  SER n 
2 22  CYS n 
2 23  THR n 
2 24  GLY n 
2 25  THR n 
2 26  SER n 
2 27  SER n 
2 28  ASP n 
2 29  VAL n 
2 30  GLY n 
2 31  GLY n 
2 32  TYR n 
2 33  ASN n 
2 34  TYR n 
2 35  VAL n 
2 36  SER n 
2 37  TRP n 
2 38  TYR n 
2 39  GLN n 
2 40  GLN n 
2 41  HIS n 
2 42  PRO n 
2 43  GLY n 
2 44  LYS n 
2 45  ALA n 
2 46  PRO n 
2 47  LYS n 
2 48  LEU n 
2 49  MET n 
2 50  ILE n 
2 51  TYR n 
2 52  ASP n 
2 53  VAL n 
2 54  SER n 
2 55  LYS n 
2 56  ARG n 
2 57  PRO n 
2 58  SER n 
2 59  GLY n 
2 60  VAL n 
2 61  SER n 
2 62  ASN n 
2 63  ARG n 
2 64  PHE n 
2 65  SER n 
2 66  GLY n 
2 67  SER n 
2 68  LYS n 
2 69  SER n 
2 70  GLY n 
2 71  ASN n 
2 72  THR n 
2 73  ALA n 
2 74  SER n 
2 75  LEU n 
2 76  THR n 
2 77  ILE n 
2 78  SER n 
2 79  GLY n 
2 80  LEU n 
2 81  GLN n 
2 82  ALA n 
2 83  GLU n 
2 84  ASP n 
2 85  GLU n 
2 86  ALA n 
2 87  ASP n 
2 88  TYR n 
2 89  TYR n 
2 90  CYS n 
2 91  SER n 
2 92  SER n 
2 93  TYR n 
2 94  THR n 
2 95  SER n 
2 96  SER n 
2 97  SER n 
2 98  THR n 
2 99  TRP n 
2 100 VAL n 
2 101 PHE n 
2 102 GLY n 
2 103 GLY n 
2 104 GLY n 
2 105 THR n 
2 106 LYS n 
2 107 LEU n 
2 108 THR n 
2 109 VAL n 
2 110 LEU n 
2 111 GLY n 
2 112 GLN n 
2 113 PRO n 
2 114 LYS n 
2 115 ALA n 
2 116 ALA n 
2 117 PRO n 
2 118 SER n 
2 119 VAL n 
2 120 THR n 
2 121 LEU n 
2 122 PHE n 
2 123 PRO n 
2 124 PRO n 
2 125 SER n 
2 126 SER n 
2 127 GLU n 
2 128 GLU n 
2 129 LEU n 
2 130 GLN n 
2 131 ALA n 
2 132 ASN n 
2 133 LYS n 
2 134 ALA n 
2 135 THR n 
2 136 LEU n 
2 137 VAL n 
2 138 CYS n 
2 139 LEU n 
2 140 ILE n 
2 141 SER n 
2 142 ASP n 
2 143 PHE n 
2 144 TYR n 
2 145 PRO n 
2 146 GLY n 
2 147 ALA n 
2 148 VAL n 
2 149 THR n 
2 150 VAL n 
2 151 ALA n 
2 152 TRP n 
2 153 LYS n 
2 154 ALA n 
2 155 ASP n 
2 156 SER n 
2 157 SER n 
2 158 PRO n 
2 159 VAL n 
2 160 LYS n 
2 161 ALA n 
2 162 GLY n 
2 163 VAL n 
2 164 GLU n 
2 165 THR n 
2 166 THR n 
2 167 THR n 
2 168 PRO n 
2 169 SER n 
2 170 LYS n 
2 171 GLN n 
2 172 SER n 
2 173 ASN n 
2 174 ASN n 
2 175 LYS n 
2 176 TYR n 
2 177 ALA n 
2 178 ALA n 
2 179 SER n 
2 180 SER n 
2 181 TYR n 
2 182 LEU n 
2 183 SER n 
2 184 LEU n 
2 185 THR n 
2 186 PRO n 
2 187 GLU n 
2 188 GLN n 
2 189 TRP n 
2 190 LYS n 
2 191 SER n 
2 192 HIS n 
2 193 ARG n 
2 194 SER n 
2 195 TYR n 
2 196 SER n 
2 197 CYS n 
2 198 GLN n 
2 199 VAL n 
2 200 THR n 
2 201 HIS n 
2 202 GLU n 
2 203 GLY n 
2 204 SER n 
2 205 THR n 
2 206 VAL n 
2 207 GLU n 
2 208 LYS n 
2 209 THR n 
2 210 VAL n 
2 211 ALA n 
2 212 PRO n 
2 213 THR n 
2 214 GLU n 
2 215 CYS n 
2 216 SER n 
3 1   GLN n 
3 2   VAL n 
3 3   GLN n 
3 4   LEU n 
3 5   VAL n 
3 6   GLN n 
3 7   SER n 
3 8   GLY n 
3 9   ALA n 
3 10  GLU n 
3 11  VAL n 
3 12  LYS n 
3 13  LYS n 
3 14  PRO n 
3 15  GLY n 
3 16  SER n 
3 17  SER n 
3 18  VAL n 
3 19  LYS n 
3 20  VAL n 
3 21  SER n 
3 22  CYS n 
3 23  LYS n 
3 24  ALA n 
3 25  SER n 
3 26  GLY n 
3 27  GLY n 
3 28  THR n 
3 29  PHE n 
3 30  SER n 
3 31  SER n 
3 32  TYR n 
3 33  ALA n 
3 34  ILE n 
3 35  SER n 
3 36  TRP n 
3 37  VAL n 
3 38  ARG n 
3 39  GLN n 
3 40  ALA n 
3 41  PRO n 
3 42  GLY n 
3 43  GLN n 
3 44  GLY n 
3 45  LEU n 
3 46  GLU n 
3 47  TRP n 
3 48  MET n 
3 49  GLY n 
3 50  GLY n 
3 51  ILE n 
3 52  ILE n 
3 53  PRO n 
3 54  ILE n 
3 55  PHE n 
3 56  GLY n 
3 57  THR n 
3 58  ALA n 
3 59  ASN n 
3 60  TYR n 
3 61  ALA n 
3 62  GLN n 
3 63  LYS n 
3 64  PHE n 
3 65  GLN n 
3 66  GLY n 
3 67  ARG n 
3 68  VAL n 
3 69  THR n 
3 70  ILE n 
3 71  THR n 
3 72  ALA n 
3 73  ASP n 
3 74  GLU n 
3 75  SER n 
3 76  THR n 
3 77  SER n 
3 78  THR n 
3 79  ALA n 
3 80  TYR n 
3 81  MET n 
3 82  GLU n 
3 83  LEU n 
3 84  SER n 
3 85  SER n 
3 86  LEU n 
3 87  ARG n 
3 88  SER n 
3 89  GLU n 
3 90  ASP n 
3 91  THR n 
3 92  ALA n 
3 93  VAL n 
3 94  TYR n 
3 95  TYR n 
3 96  CYS n 
3 97  ALA n 
3 98  ARG n 
3 99  GLY n 
3 100 GLN n 
3 101 LEU n 
3 102 ARG n 
3 103 TYR n 
3 104 PHE n 
3 105 ASP n 
3 106 TRP n 
3 107 PRO n 
3 108 THR n 
3 109 ILE n 
3 110 PRO n 
3 111 SER n 
3 112 SER n 
3 113 TYR n 
3 114 TYR n 
3 115 GLY n 
3 116 MET n 
3 117 ASP n 
3 118 VAL n 
3 119 TRP n 
3 120 GLY n 
3 121 GLN n 
3 122 GLY n 
3 123 THR n 
3 124 THR n 
3 125 VAL n 
3 126 THR n 
3 127 VAL n 
3 128 SER n 
3 129 SER n 
3 130 ALA n 
3 131 SER n 
3 132 THR n 
3 133 LYS n 
3 134 GLY n 
3 135 PRO n 
3 136 SER n 
3 137 VAL n 
3 138 PHE n 
3 139 PRO n 
3 140 LEU n 
3 141 ALA n 
3 142 PRO n 
3 143 SER n 
3 144 SER n 
3 145 LYS n 
3 146 SER n 
3 147 THR n 
3 148 SER n 
3 149 GLY n 
3 150 GLY n 
3 151 THR n 
3 152 ALA n 
3 153 ALA n 
3 154 LEU n 
3 155 GLY n 
3 156 CYS n 
3 157 LEU n 
3 158 VAL n 
3 159 LYS n 
3 160 ASP n 
3 161 TYR n 
3 162 PHE n 
3 163 PRO n 
3 164 GLU n 
3 165 PRO n 
3 166 VAL n 
3 167 THR n 
3 168 VAL n 
3 169 SER n 
3 170 TRP n 
3 171 ASN n 
3 172 SER n 
3 173 GLY n 
3 174 ALA n 
3 175 LEU n 
3 176 THR n 
3 177 SER n 
3 178 GLY n 
3 179 VAL n 
3 180 HIS n 
3 181 THR n 
3 182 PHE n 
3 183 PRO n 
3 184 ALA n 
3 185 VAL n 
3 186 LEU n 
3 187 GLN n 
3 188 SER n 
3 189 SER n 
3 190 GLY n 
3 191 LEU n 
3 192 TYR n 
3 193 SER n 
3 194 LEU n 
3 195 SER n 
3 196 SER n 
3 197 VAL n 
3 198 VAL n 
3 199 THR n 
3 200 VAL n 
3 201 PRO n 
3 202 SER n 
3 203 SER n 
3 204 SER n 
3 205 LEU n 
3 206 GLY n 
3 207 THR n 
3 208 GLN n 
3 209 THR n 
3 210 TYR n 
3 211 ILE n 
3 212 CYS n 
3 213 ASN n 
3 214 VAL n 
3 215 ASN n 
3 216 HIS n 
3 217 LYS n 
3 218 PRO n 
3 219 SER n 
3 220 ASN n 
3 221 THR n 
3 222 LYS n 
3 223 VAL n 
3 224 ASP n 
3 225 LYS n 
3 226 ARG n 
3 227 VAL n 
3 228 GLU n 
3 229 PRO n 
3 230 LYS n 
3 231 SER n 
3 232 CYS n 
3 233 ASP n 
3 234 LYS n 
3 235 THR n 
3 236 HIS n 
4 1   GLU n 
4 2   VAL n 
4 3   GLN n 
4 4   LEU n 
4 5   VAL n 
4 6   GLU n 
4 7   SER n 
4 8   GLY n 
4 9   GLY n 
4 10  ARG n 
4 11  ALA n 
4 12  LEU n 
4 13  ARG n 
4 14  PRO n 
4 15  GLY n 
4 16  GLY n 
4 17  SER n 
4 18  LEU n 
4 19  ARG n 
4 20  LEU n 
4 21  SER n 
4 22  CYS n 
4 23  ALA n 
4 24  ALA n 
4 25  SER n 
4 26  GLY n 
4 27  PHE n 
4 28  LYS n 
4 29  PHE n 
4 30  ASP n 
4 31  ASP n 
4 32  TYR n 
4 33  ALA n 
4 34  MET n 
4 35  SER n 
4 36  TRP n 
4 37  VAL n 
4 38  ARG n 
4 39  GLN n 
4 40  VAL n 
4 41  PRO n 
4 42  GLY n 
4 43  LYS n 
4 44  GLY n 
4 45  LEU n 
4 46  GLU n 
4 47  PHE n 
4 48  VAL n 
4 49  SER n 
4 50  GLY n 
4 51  LEU n 
4 52  ASN n 
4 53  TRP n 
4 54  ASN n 
4 55  GLY n 
4 56  ASP n 
4 57  ILE n 
4 58  THR n 
4 59  ALA n 
4 60  TYR n 
4 61  THR n 
4 62  ASP n 
4 63  SER n 
4 64  VAL n 
4 65  LYS n 
4 66  GLY n 
4 67  ARG n 
4 68  PHE n 
4 69  THR n 
4 70  VAL n 
4 71  SER n 
4 72  ARG n 
4 73  ASP n 
4 74  ASN n 
4 75  ALA n 
4 76  LYS n 
4 77  ASN n 
4 78  SER n 
4 79  LEU n 
4 80  TYR n 
4 81  LEU n 
4 82  HIS n 
4 83  ILE n 
4 84  ASN n 
4 85  SER n 
4 86  PRO n 
4 87  LYS n 
4 88  PRO n 
4 89  GLU n 
4 90  ASP n 
4 91  THR n 
4 92  ALA n 
4 93  LEU n 
4 94  TYR n 
4 95  TYR n 
4 96  CYS n 
4 97  ALA n 
4 98  ARG n 
4 99  THR n 
4 100 SER n 
4 101 SER n 
4 102 TRP n 
4 103 GLY n 
4 104 ASP n 
4 105 TYR n 
4 106 THR n 
4 107 ARG n 
4 108 GLY n 
4 109 PRO n 
4 110 GLU n 
4 111 PRO n 
4 112 LYS n 
4 113 ILE n 
4 114 THR n 
4 115 TRP n 
4 116 TYR n 
4 117 PHE n 
4 118 ASP n 
4 119 LEU n 
4 120 TRP n 
4 121 GLY n 
4 122 ARG n 
4 123 GLY n 
4 124 THR n 
4 125 LEU n 
4 126 VAL n 
4 127 THR n 
4 128 VAL n 
4 129 SER n 
4 130 SER n 
4 131 ALA n 
4 132 SER n 
4 133 THR n 
4 134 LYS n 
4 135 GLY n 
4 136 PRO n 
4 137 SER n 
4 138 VAL n 
4 139 PHE n 
4 140 PRO n 
4 141 LEU n 
4 142 ALA n 
4 143 PRO n 
4 144 SER n 
4 145 SER n 
4 146 LYS n 
4 147 SER n 
4 148 THR n 
4 149 SER n 
4 150 GLY n 
4 151 GLY n 
4 152 THR n 
4 153 ALA n 
4 154 ALA n 
4 155 LEU n 
4 156 GLY n 
4 157 CYS n 
4 158 LEU n 
4 159 VAL n 
4 160 LYS n 
4 161 ASP n 
4 162 TYR n 
4 163 PHE n 
4 164 PRO n 
4 165 GLU n 
4 166 PRO n 
4 167 VAL n 
4 168 THR n 
4 169 VAL n 
4 170 SER n 
4 171 TRP n 
4 172 ASN n 
4 173 SER n 
4 174 GLY n 
4 175 ALA n 
4 176 LEU n 
4 177 THR n 
4 178 SER n 
4 179 GLY n 
4 180 VAL n 
4 181 HIS n 
4 182 THR n 
4 183 PHE n 
4 184 PRO n 
4 185 ALA n 
4 186 VAL n 
4 187 LEU n 
4 188 GLN n 
4 189 SER n 
4 190 SER n 
4 191 GLY n 
4 192 LEU n 
4 193 TYR n 
4 194 SER n 
4 195 LEU n 
4 196 SER n 
4 197 SER n 
4 198 VAL n 
4 199 VAL n 
4 200 THR n 
4 201 VAL n 
4 202 PRO n 
4 203 SER n 
4 204 SER n 
4 205 SER n 
4 206 LEU n 
4 207 GLY n 
4 208 THR n 
4 209 GLN n 
4 210 THR n 
4 211 TYR n 
4 212 ILE n 
4 213 CYS n 
4 214 ASN n 
4 215 VAL n 
4 216 ASN n 
4 217 HIS n 
4 218 LYS n 
4 219 PRO n 
4 220 SER n 
4 221 ASN n 
4 222 THR n 
4 223 LYS n 
4 224 VAL n 
4 225 ASP n 
4 226 LYS n 
4 227 ARG n 
4 228 VAL n 
4 229 GLU n 
4 230 PRO n 
4 231 LYS n 
4 232 SER n 
5 1   ASP n 
5 2   ASP n 
5 3   ILE n 
5 4   GLN n 
5 5   LEU n 
5 6   THR n 
5 7   GLN n 
5 8   SER n 
5 9   PRO n 
5 10  SER n 
5 11  PHE n 
5 12  LEU n 
5 13  SER n 
5 14  ALA n 
5 15  SER n 
5 16  VAL n 
5 17  GLY n 
5 18  ASP n 
5 19  ARG n 
5 20  ILE n 
5 21  THR n 
5 22  ILE n 
5 23  THR n 
5 24  CYS n 
5 25  ARG n 
5 26  ALA n 
5 27  SER n 
5 28  GLN n 
5 29  GLY n 
5 30  ILE n 
5 31  ASP n 
5 32  GLY n 
5 33  TYR n 
5 34  LEU n 
5 35  ALA n 
5 36  TRP n 
5 37  TYR n 
5 38  GLN n 
5 39  GLN n 
5 40  ARG n 
5 41  PRO n 
5 42  GLY n 
5 43  LYS n 
5 44  ALA n 
5 45  PRO n 
5 46  ASN n 
5 47  LEU n 
5 48  LEU n 
5 49  ILE n 
5 50  TYR n 
5 51  ALA n 
5 52  ALA n 
5 53  SER n 
5 54  LEU n 
5 55  LEU n 
5 56  GLN n 
5 57  SER n 
5 58  GLY n 
5 59  VAL n 
5 60  PRO n 
5 61  SER n 
5 62  ARG n 
5 63  PHE n 
5 64  SER n 
5 65  GLY n 
5 66  SER n 
5 67  GLY n 
5 68  TYR n 
5 69  GLY n 
5 70  THR n 
5 71  GLU n 
5 72  PHE n 
5 73  THR n 
5 74  LEU n 
5 75  THR n 
5 76  ILE n 
5 77  SER n 
5 78  SER n 
5 79  LEU n 
5 80  GLN n 
5 81  PRO n 
5 82  GLU n 
5 83  ASP n 
5 84  PHE n 
5 85  ALA n 
5 86  THR n 
5 87  TYR n 
5 88  TYR n 
5 89  CYS n 
5 90  GLN n 
5 91  HIS n 
5 92  LEU n 
5 93  ASP n 
5 94  SER n 
5 95  TYR n 
5 96  PRO n 
5 97  LEU n 
5 98  PHE n 
5 99  THR n 
5 100 PHE n 
5 101 GLY n 
5 102 PRO n 
5 103 GLY n 
5 104 THR n 
5 105 LYS n 
5 106 VAL n 
5 107 ASP n 
5 108 ILE n 
5 109 LYS n 
5 110 ARG n 
5 111 THR n 
5 112 VAL n 
5 113 ALA n 
5 114 ALA n 
5 115 PRO n 
5 116 SER n 
5 117 VAL n 
5 118 PHE n 
5 119 ILE n 
5 120 PHE n 
5 121 PRO n 
5 122 PRO n 
5 123 SER n 
5 124 ASP n 
5 125 GLU n 
5 126 GLN n 
5 127 LEU n 
5 128 LYS n 
5 129 SER n 
5 130 GLY n 
5 131 THR n 
5 132 ALA n 
5 133 SER n 
5 134 VAL n 
5 135 VAL n 
5 136 CYS n 
5 137 LEU n 
5 138 LEU n 
5 139 ASN n 
5 140 ASN n 
5 141 PHE n 
5 142 TYR n 
5 143 PRO n 
5 144 ARG n 
5 145 GLU n 
5 146 ALA n 
5 147 LYS n 
5 148 VAL n 
5 149 GLN n 
5 150 TRP n 
5 151 LYS n 
5 152 VAL n 
5 153 ASP n 
5 154 ASN n 
5 155 ALA n 
5 156 LEU n 
5 157 GLN n 
5 158 SER n 
5 159 GLY n 
5 160 ASN n 
5 161 SER n 
5 162 GLN n 
5 163 GLU n 
5 164 SER n 
5 165 VAL n 
5 166 THR n 
5 167 GLU n 
5 168 GLN n 
5 169 ASP n 
5 170 SER n 
5 171 LYS n 
5 172 ASP n 
5 173 SER n 
5 174 THR n 
5 175 TYR n 
5 176 SER n 
5 177 LEU n 
5 178 SER n 
5 179 SER n 
5 180 THR n 
5 181 LEU n 
5 182 THR n 
5 183 LEU n 
5 184 SER n 
5 185 LYS n 
5 186 ALA n 
5 187 ASP n 
5 188 TYR n 
5 189 GLU n 
5 190 LYS n 
5 191 HIS n 
5 192 LYS n 
5 193 VAL n 
5 194 TYR n 
5 195 ALA n 
5 196 CYS n 
5 197 GLU n 
5 198 VAL n 
5 199 THR n 
5 200 HIS n 
5 201 GLN n 
5 202 GLY n 
5 203 LEU n 
5 204 SER n 
5 205 SER n 
5 206 PRO n 
5 207 VAL n 
5 208 THR n 
5 209 LYS n 
5 210 SER n 
5 211 PHE n 
5 212 ASN n 
5 213 ARG n 
5 214 GLY n 
5 215 GLU n 
5 216 CYS n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 379 ? ? NA ? ? ? ? ? ? 'Influenza A virus' 11320 ? ? ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? 
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 216 ? ? ?  ? ? ? ? ? ? 'Homo sapiens'      9606  ? ? ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? 
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
3 1 sample 'Biological sequence' 1 236 ? ? ?  ? ? ? ? ? ? 'Homo sapiens'      9606  ? ? ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? 
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
4 1 sample 'Biological sequence' 1 232 ? ? ?  ? ? ? ? ? ? 'Homo sapiens'      9606  ? ? ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? 
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
5 1 sample 'Biological sequence' 1 216 ? ? ?  ? ? ? ? ? ? 'Homo sapiens'      9606  ? ? ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? 
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
_pdbx_entity_branch.entity_id   6 
_pdbx_entity_branch.type        oligosaccharide 
# 
loop_
_pdbx_entity_branch_descriptor.ordinal 
_pdbx_entity_branch_descriptor.entity_id 
_pdbx_entity_branch_descriptor.descriptor 
_pdbx_entity_branch_descriptor.type 
_pdbx_entity_branch_descriptor.program 
_pdbx_entity_branch_descriptor.program_version 
1 6 DGlcpNAcb1-4DGlcpNAcb1-ROH                            'Glycam Condensed Sequence' GMML       1.0   
2 6 'WURCS=2.0/1,2,1/[a2122h-1b_1-5_2*NCC/3=O]/1-1/a4-b1' WURCS                       PDB2Glycan 1.1.0 
3 6 '[][D-1-deoxy-GlcpNAc]{[(4+1)][b-D-GlcpNAc]{}}'       LINUCS                      PDB-CARE   ?     
# 
_pdbx_entity_branch_link.link_id                    1 
_pdbx_entity_branch_link.entity_id                  6 
_pdbx_entity_branch_link.entity_branch_list_num_1   2 
_pdbx_entity_branch_link.comp_id_1                  NAG 
_pdbx_entity_branch_link.atom_id_1                  C1 
_pdbx_entity_branch_link.leaving_atom_id_1          O1 
_pdbx_entity_branch_link.entity_branch_list_num_2   1 
_pdbx_entity_branch_link.comp_id_2                  NAG 
_pdbx_entity_branch_link.atom_id_2                  O4 
_pdbx_entity_branch_link.leaving_atom_id_2          HO4 
_pdbx_entity_branch_link.value_order                sing 
_pdbx_entity_branch_link.details                    ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking'          y ALANINE                                  ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking'          y ARGININE                                 ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking'          y ASPARAGINE                               ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking'          y 'ASPARTIC ACID'                          ? 'C4 H7 N O4'     133.103 
CA  non-polymer                  . 'CALCIUM ION'                            ? 'Ca 2'           40.078  
CYS 'L-peptide linking'          y CYSTEINE                                 ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking'          y GLUTAMINE                                ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking'          y 'GLUTAMIC ACID'                          ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'            y GLYCINE                                  ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking'          y HISTIDINE                                ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking'          y ISOLEUCINE                               ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking'          y LEUCINE                                  ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking'          y LYSINE                                   ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking'          y METHIONINE                               ? 'C5 H11 N O2 S'  149.211 
NAG 'D-saccharide, beta linking' . 2-acetamido-2-deoxy-beta-D-glucopyranose 
;N-acetyl-beta-D-glucosamine; 2-acetamido-2-deoxy-beta-D-glucose; 2-acetamido-2-deoxy-D-glucose; 2-acetamido-2-deoxy-glucose; N-ACETYL-D-GLUCOSAMINE
;
'C8 H15 N O6'    221.208 
PHE 'L-peptide linking'          y PHENYLALANINE                            ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking'          y PROLINE                                  ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking'          y SERINE                                   ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking'          y THREONINE                                ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking'          y TRYPTOPHAN                               ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking'          y TYROSINE                                 ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking'          y VALINE                                   ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_chem_comp_identifier.comp_id 
_pdbx_chem_comp_identifier.type 
_pdbx_chem_comp_identifier.program 
_pdbx_chem_comp_identifier.program_version 
_pdbx_chem_comp_identifier.identifier 
NAG 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DGlcpNAcb                      
NAG 'COMMON NAME'                         GMML     1.0 N-acetyl-b-D-glucopyranosamine 
NAG 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 b-D-GlcpNAc                    
NAG 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 GlcNAc                         
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   ARG 1   82  82  ARG ARG A . n 
A 1 2   THR 2   83  83  THR THR A . n 
A 1 3   PHE 3   84  84  PHE PHE A . n 
A 1 4   LEU 4   85  85  LEU LEU A . n 
A 1 5   ASN 5   86  86  ASN ASN A . n 
A 1 6   LEU 6   87  87  LEU LEU A . n 
A 1 7   THR 7   88  88  THR THR A . n 
A 1 8   LYS 8   89  89  LYS LYS A . n 
A 1 9   PRO 9   90  90  PRO PRO A . n 
A 1 10  LEU 10  91  91  LEU LEU A . n 
A 1 11  CYS 11  92  92  CYS CYS A . n 
A 1 12  GLU 12  93  93  GLU GLU A . n 
A 1 13  VAL 13  94  94  VAL VAL A . n 
A 1 14  ASN 14  95  95  ASN ASN A . n 
A 1 15  SER 15  96  96  SER SER A . n 
A 1 16  TRP 16  97  97  TRP TRP A . n 
A 1 17  HIS 17  98  98  HIS HIS A . n 
A 1 18  ILE 18  99  99  ILE ILE A . n 
A 1 19  LEU 19  100 100 LEU LEU A . n 
A 1 20  SER 20  101 101 SER SER A . n 
A 1 21  LYS 21  102 ?   ?   ?   A . n 
A 1 22  ASP 22  103 ?   ?   ?   A . n 
A 1 23  ASN 23  104 ?   ?   ?   A . n 
A 1 24  ALA 24  105 ?   ?   ?   A . n 
A 1 25  ILE 25  106 ?   ?   ?   A . n 
A 1 26  ARG 26  107 ?   ?   ?   A . n 
A 1 27  ILE 27  108 ?   ?   ?   A . n 
A 1 28  GLY 28  109 ?   ?   ?   A . n 
A 1 29  GLU 29  110 ?   ?   ?   A . n 
A 1 30  ASP 30  111 ?   ?   ?   A . n 
A 1 31  ALA 31  112 112 ALA ALA A . n 
A 1 32  HIS 32  113 113 HIS HIS A . n 
A 1 33  ILE 33  114 114 ILE ILE A . n 
A 1 34  LEU 34  115 115 LEU LEU A . n 
A 1 35  VAL 35  116 116 VAL VAL A . n 
A 1 36  THR 36  117 117 THR THR A . n 
A 1 37  ARG 37  118 118 ARG ARG A . n 
A 1 38  GLU 38  119 119 GLU GLU A . n 
A 1 39  PRO 39  120 120 PRO PRO A . n 
A 1 40  TYR 40  121 121 TYR TYR A . n 
A 1 41  LEU 41  122 122 LEU LEU A . n 
A 1 42  SER 42  123 123 SER SER A . n 
A 1 43  CYS 43  124 124 CYS CYS A . n 
A 1 44  ASP 44  125 125 ASP ASP A . n 
A 1 45  PRO 45  126 126 PRO PRO A . n 
A 1 46  GLN 46  127 127 GLN GLN A . n 
A 1 47  GLY 47  128 128 GLY GLY A . n 
A 1 48  CYS 48  129 129 CYS CYS A . n 
A 1 49  ARG 49  130 130 ARG ARG A . n 
A 1 50  MET 50  131 131 MET MET A . n 
A 1 51  PHE 51  132 132 PHE PHE A . n 
A 1 52  ALA 52  133 133 ALA ALA A . n 
A 1 53  LEU 53  134 134 LEU LEU A . n 
A 1 54  SER 54  135 135 SER SER A . n 
A 1 55  GLN 55  136 136 GLN GLN A . n 
A 1 56  GLY 56  137 137 GLY GLY A . n 
A 1 57  THR 57  138 ?   ?   ?   A . n 
A 1 58  THR 58  139 ?   ?   ?   A . n 
A 1 59  LEU 59  140 ?   ?   ?   A . n 
A 1 60  ARG 60  141 ?   ?   ?   A . n 
A 1 61  GLY 61  142 ?   ?   ?   A . n 
A 1 62  ARG 62  143 ?   ?   ?   A . n 
A 1 63  HIS 63  144 ?   ?   ?   A . n 
A 1 64  ALA 64  145 ?   ?   ?   A . n 
A 1 65  ASN 65  146 ?   ?   ?   A . n 
A 1 66  GLY 66  147 ?   ?   ?   A . n 
A 1 67  THR 67  148 ?   ?   ?   A . n 
A 1 68  ILE 68  149 ?   ?   ?   A . n 
A 1 69  HIS 69  150 ?   ?   ?   A . n 
A 1 70  ASP 70  151 ?   ?   ?   A . n 
A 1 71  LYS 71  152 ?   ?   ?   A . n 
A 1 72  SER 72  153 ?   ?   ?   A . n 
A 1 73  PRO 73  154 154 PRO PRO A . n 
A 1 74  PHE 74  155 155 PHE PHE A . n 
A 1 75  ARG 75  156 156 ARG ARG A . n 
A 1 76  ALA 76  157 157 ALA ALA A . n 
A 1 77  LEU 77  158 158 LEU LEU A . n 
A 1 78  ILE 78  159 159 ILE ILE A . n 
A 1 79  SER 79  160 160 SER SER A . n 
A 1 80  TRP 80  161 161 TRP TRP A . n 
A 1 81  GLU 81  162 162 GLU GLU A . n 
A 1 82  MET 82  163 163 MET MET A . n 
A 1 83  GLY 83  164 164 GLY GLY A . n 
A 1 84  GLN 84  165 165 GLN GLN A . n 
A 1 85  ALA 85  166 166 ALA ALA A . n 
A 1 86  PRO 86  167 167 PRO PRO A . n 
A 1 87  SER 87  168 168 SER SER A . n 
A 1 88  PRO 88  169 169 PRO PRO A . n 
A 1 89  TYR 89  170 170 TYR TYR A . n 
A 1 90  ASN 90  171 171 ASN ASN A . n 
A 1 91  THR 91  172 172 THR THR A . n 
A 1 92  ARG 92  173 173 ARG ARG A . n 
A 1 93  VAL 93  174 174 VAL VAL A . n 
A 1 94  GLU 94  175 175 GLU GLU A . n 
A 1 95  CYS 95  176 176 CYS CYS A . n 
A 1 96  ILE 96  177 177 ILE ILE A . n 
A 1 97  GLY 97  178 178 GLY GLY A . n 
A 1 98  TRP 98  179 179 TRP TRP A . n 
A 1 99  SER 99  180 180 SER SER A . n 
A 1 100 SER 100 181 181 SER SER A . n 
A 1 101 THR 101 182 182 THR THR A . n 
A 1 102 SER 102 183 183 SER SER A . n 
A 1 103 CYS 103 184 184 CYS CYS A . n 
A 1 104 HIS 104 185 185 HIS HIS A . n 
A 1 105 ASP 105 186 186 ASP ASP A . n 
A 1 106 GLY 106 187 187 GLY GLY A . n 
A 1 107 ILE 107 188 188 ILE ILE A . n 
A 1 108 SER 108 189 189 SER SER A . n 
A 1 109 ARG 109 190 190 ARG ARG A . n 
A 1 110 MET 110 191 191 MET MET A . n 
A 1 111 SER 111 192 192 SER SER A . n 
A 1 112 ILE 112 193 193 ILE ILE A . n 
A 1 113 CYS 113 194 194 CYS CYS A . n 
A 1 114 ILE 114 195 195 ILE ILE A . n 
A 1 115 SER 115 196 196 SER SER A . n 
A 1 116 GLY 116 197 197 GLY GLY A . n 
A 1 117 PRO 117 198 198 PRO PRO A . n 
A 1 118 ASN 118 199 199 ASN ASN A . n 
A 1 119 ASN 119 200 200 ASN ASN A . n 
A 1 120 ASN 120 201 201 ASN ASN A . n 
A 1 121 ALA 121 202 202 ALA ALA A . n 
A 1 122 SER 122 203 203 SER SER A . n 
A 1 123 ALA 123 204 204 ALA ALA A . n 
A 1 124 VAL 124 205 205 VAL VAL A . n 
A 1 125 VAL 125 206 206 VAL VAL A . n 
A 1 126 TRP 126 207 207 TRP TRP A . n 
A 1 127 TYR 127 208 208 TYR TYR A . n 
A 1 128 ARG 128 209 209 ARG ARG A . n 
A 1 129 GLY 129 210 210 GLY GLY A . n 
A 1 130 ARG 130 211 211 ARG ARG A . n 
A 1 131 PRO 131 212 212 PRO PRO A . n 
A 1 132 VAL 132 213 213 VAL VAL A . n 
A 1 133 THR 133 214 214 THR THR A . n 
A 1 134 GLU 134 215 215 GLU GLU A . n 
A 1 135 ILE 135 216 216 ILE ILE A . n 
A 1 136 PRO 136 217 217 PRO PRO A . n 
A 1 137 SER 137 218 218 SER SER A . n 
A 1 138 TRP 138 219 219 TRP TRP A . n 
A 1 139 VAL 139 220 220 VAL VAL A . n 
A 1 140 GLY 140 221 221 GLY GLY A . n 
A 1 141 ASN 141 222 222 ASN ASN A . n 
A 1 142 ILE 142 223 223 ILE ILE A . n 
A 1 143 LEU 143 224 224 LEU LEU A . n 
A 1 144 ARG 144 225 225 ARG ARG A . n 
A 1 145 THR 145 226 226 THR THR A . n 
A 1 146 GLN 146 227 227 GLN GLN A . n 
A 1 147 GLU 147 228 228 GLU GLU A . n 
A 1 148 SER 148 229 229 SER SER A . n 
A 1 149 GLU 149 230 230 GLU GLU A . n 
A 1 150 CYS 150 231 231 CYS CYS A . n 
A 1 151 VAL 151 232 232 VAL VAL A . n 
A 1 152 CYS 152 233 233 CYS CYS A . n 
A 1 153 HIS 153 234 234 HIS HIS A . n 
A 1 154 LYS 154 235 235 LYS LYS A . n 
A 1 155 GLY 155 236 236 GLY GLY A . n 
A 1 156 ILE 156 237 237 ILE ILE A . n 
A 1 157 CYS 157 238 238 CYS CYS A . n 
A 1 158 PRO 158 239 239 PRO PRO A . n 
A 1 159 VAL 159 240 240 VAL VAL A . n 
A 1 160 VAL 160 241 241 VAL VAL A . n 
A 1 161 MET 161 242 242 MET MET A . n 
A 1 162 THR 162 243 243 THR THR A . n 
A 1 163 ASP 163 244 244 ASP ASP A . n 
A 1 164 GLY 164 245 245 GLY GLY A . n 
A 1 165 PRO 165 246 246 PRO PRO A . n 
A 1 166 ALA 166 247 247 ALA ALA A . n 
A 1 167 ASN 167 248 248 ASN ASN A . n 
A 1 168 ASN 168 249 249 ASN ASN A . n 
A 1 169 LYS 169 250 250 LYS LYS A . n 
A 1 170 ALA 170 251 251 ALA ALA A . n 
A 1 171 ALA 171 252 252 ALA ALA A . n 
A 1 172 THR 172 253 253 THR THR A . n 
A 1 173 LYS 173 254 254 LYS LYS A . n 
A 1 174 ILE 174 255 255 ILE ILE A . n 
A 1 175 ILE 175 256 256 ILE ILE A . n 
A 1 176 TYR 176 257 257 TYR TYR A . n 
A 1 177 PHE 177 258 258 PHE PHE A . n 
A 1 178 LYS 178 259 259 LYS LYS A . n 
A 1 179 GLU 179 260 260 GLU GLU A . n 
A 1 180 GLY 180 261 261 GLY GLY A . n 
A 1 181 LYS 181 262 262 LYS LYS A . n 
A 1 182 ILE 182 263 263 ILE ILE A . n 
A 1 183 GLN 183 264 264 GLN GLN A . n 
A 1 184 LYS 184 265 265 LYS LYS A . n 
A 1 185 ILE 185 266 266 ILE ILE A . n 
A 1 186 GLU 186 267 267 GLU GLU A . n 
A 1 187 GLU 187 268 268 GLU GLU A . n 
A 1 188 LEU 188 269 269 LEU LEU A . n 
A 1 189 GLN 189 270 270 GLN GLN A . n 
A 1 190 GLY 190 271 271 GLY GLY A . n 
A 1 191 ASN 191 272 272 ASN ASN A . n 
A 1 192 ALA 192 273 273 ALA ALA A . n 
A 1 193 GLN 193 274 274 GLN GLN A . n 
A 1 194 HIS 194 275 275 HIS HIS A . n 
A 1 195 ILE 195 276 276 ILE ILE A . n 
A 1 196 GLU 196 277 277 GLU GLU A . n 
A 1 197 GLU 197 278 278 GLU GLU A . n 
A 1 198 CYS 198 279 279 CYS CYS A . n 
A 1 199 SER 199 280 280 SER SER A . n 
A 1 200 CYS 200 281 281 CYS CYS A . n 
A 1 201 TYR 201 282 282 TYR TYR A . n 
A 1 202 GLY 202 283 283 GLY GLY A . n 
A 1 203 ALA 203 284 284 ALA ALA A . n 
A 1 204 ALA 204 285 285 ALA ALA A . n 
A 1 205 GLY 205 286 286 GLY GLY A . n 
A 1 206 MET 206 287 287 MET MET A . n 
A 1 207 ILE 207 288 288 ILE ILE A . n 
A 1 208 LYS 208 289 289 LYS LYS A . n 
A 1 209 CYS 209 290 290 CYS CYS A . n 
A 1 210 VAL 210 291 291 VAL VAL A . n 
A 1 211 CYS 211 292 292 CYS CYS A . n 
A 1 212 ARG 212 293 293 ARG ARG A . n 
A 1 213 ASP 213 294 294 ASP ASP A . n 
A 1 214 ASN 214 295 295 ASN ASN A . n 
A 1 215 TRP 215 296 296 TRP TRP A . n 
A 1 216 LYS 216 297 297 LYS LYS A . n 
A 1 217 GLY 217 298 298 GLY GLY A . n 
A 1 218 ALA 218 299 299 ALA ALA A . n 
A 1 219 ASN 219 300 300 ASN ASN A . n 
A 1 220 ARG 220 301 301 ARG ARG A . n 
A 1 221 PRO 221 302 302 PRO PRO A . n 
A 1 222 ILE 222 303 303 ILE ILE A . n 
A 1 223 ILE 223 304 304 ILE ILE A . n 
A 1 224 THR 224 305 305 THR THR A . n 
A 1 225 ILE 225 306 306 ILE ILE A . n 
A 1 226 ASP 226 307 307 ASP ASP A . n 
A 1 227 PRO 227 308 308 PRO PRO A . n 
A 1 228 GLU 228 309 309 GLU GLU A . n 
A 1 229 MET 229 310 310 MET MET A . n 
A 1 230 MET 230 311 311 MET MET A . n 
A 1 231 THR 231 312 312 THR THR A . n 
A 1 232 HIS 232 313 313 HIS HIS A . n 
A 1 233 THR 233 314 314 THR THR A . n 
A 1 234 SER 234 315 315 SER SER A . n 
A 1 235 LYS 235 316 316 LYS LYS A . n 
A 1 236 TYR 236 317 317 TYR TYR A . n 
A 1 237 LEU 237 318 318 LEU LEU A . n 
A 1 238 CYS 238 319 319 CYS CYS A . n 
A 1 239 SER 239 320 320 SER SER A . n 
A 1 240 LYS 240 321 321 LYS LYS A . n 
A 1 241 ILE 241 322 322 ILE ILE A . n 
A 1 242 LEU 242 323 323 LEU LEU A . n 
A 1 243 THR 243 324 324 THR THR A . n 
A 1 244 ASP 244 325 325 ASP ASP A . n 
A 1 245 THR 245 326 326 THR THR A . n 
A 1 246 SER 246 327 327 SER SER A . n 
A 1 247 ARG 247 328 328 ARG ARG A . n 
A 1 248 PRO 248 329 329 PRO PRO A . n 
A 1 249 ASN 249 330 330 ASN ASN A . n 
A 1 250 ASP 250 331 331 ASP ASP A . n 
A 1 251 PRO 251 332 332 PRO PRO A . n 
A 1 252 THR 252 333 333 THR THR A . n 
A 1 253 ASN 253 334 334 ASN ASN A . n 
A 1 254 GLY 254 335 335 GLY GLY A . n 
A 1 255 ASN 255 336 336 ASN ASN A . n 
A 1 256 CYS 256 337 337 CYS CYS A . n 
A 1 257 ASP 257 338 338 ASP ASP A . n 
A 1 258 GLU 258 339 339 GLU GLU A . n 
A 1 259 PRO 259 340 340 PRO PRO A . n 
A 1 260 ILE 260 341 341 ILE ILE A . n 
A 1 261 THR 261 342 342 THR THR A . n 
A 1 262 GLY 262 343 343 GLY GLY A . n 
A 1 263 GLY 263 344 344 GLY GLY A . n 
A 1 264 SER 264 345 345 SER SER A . n 
A 1 265 PRO 265 346 346 PRO PRO A . n 
A 1 266 ASP 266 347 347 ASP ASP A . n 
A 1 267 PRO 267 348 348 PRO PRO A . n 
A 1 268 GLY 268 349 349 GLY GLY A . n 
A 1 269 VAL 269 350 350 VAL VAL A . n 
A 1 270 LYS 270 351 351 LYS LYS A . n 
A 1 271 GLY 271 352 352 GLY GLY A . n 
A 1 272 PHE 272 353 353 PHE PHE A . n 
A 1 273 ALA 273 354 354 ALA ALA A . n 
A 1 274 PHE 274 355 355 PHE PHE A . n 
A 1 275 LEU 275 356 356 LEU LEU A . n 
A 1 276 ASP 276 357 357 ASP ASP A . n 
A 1 277 GLY 277 358 358 GLY GLY A . n 
A 1 278 GLU 278 359 359 GLU GLU A . n 
A 1 279 ASN 279 360 360 ASN ASN A . n 
A 1 280 SER 280 361 361 SER SER A . n 
A 1 281 TRP 281 362 362 TRP TRP A . n 
A 1 282 LEU 282 363 363 LEU LEU A . n 
A 1 283 GLY 283 364 364 GLY GLY A . n 
A 1 284 ARG 284 365 365 ARG ARG A . n 
A 1 285 THR 285 366 366 THR THR A . n 
A 1 286 ILE 286 367 367 ILE ILE A . n 
A 1 287 SER 287 368 368 SER SER A . n 
A 1 288 LYS 288 369 369 LYS LYS A . n 
A 1 289 ASP 289 370 370 ASP ASP A . n 
A 1 290 SER 290 371 371 SER SER A . n 
A 1 291 ARG 291 372 372 ARG ARG A . n 
A 1 292 SER 292 373 373 SER SER A . n 
A 1 293 GLY 293 374 374 GLY GLY A . n 
A 1 294 TYR 294 375 375 TYR TYR A . n 
A 1 295 GLU 295 376 376 GLU GLU A . n 
A 1 296 MET 296 377 377 MET MET A . n 
A 1 297 LEU 297 378 378 LEU LEU A . n 
A 1 298 LYS 298 379 379 LYS LYS A . n 
A 1 299 VAL 299 380 380 VAL VAL A . n 
A 1 300 PRO 300 381 381 PRO PRO A . n 
A 1 301 ASN 301 382 382 ASN ASN A . n 
A 1 302 ALA 302 383 383 ALA ALA A . n 
A 1 303 GLU 303 384 384 GLU GLU A . n 
A 1 304 THR 304 385 385 THR THR A . n 
A 1 305 ASP 305 386 386 ASP ASP A . n 
A 1 306 THR 306 387 387 THR THR A . n 
A 1 307 GLN 307 388 388 GLN GLN A . n 
A 1 308 SER 308 389 389 SER SER A . n 
A 1 309 GLY 309 390 390 GLY GLY A . n 
A 1 310 PRO 310 391 391 PRO PRO A . n 
A 1 311 THR 311 392 392 THR THR A . n 
A 1 312 SER 312 393 393 SER SER A . n 
A 1 313 TYR 313 394 394 TYR TYR A . n 
A 1 314 GLN 314 395 395 GLN GLN A . n 
A 1 315 LEU 315 396 396 LEU LEU A . n 
A 1 316 ILE 316 397 397 ILE ILE A . n 
A 1 317 VAL 317 398 398 VAL VAL A . n 
A 1 318 ASN 318 399 399 ASN ASN A . n 
A 1 319 ASN 319 400 400 ASN ASN A . n 
A 1 320 GLN 320 401 401 GLN GLN A . n 
A 1 321 ASN 321 402 402 ASN ASN A . n 
A 1 322 TRP 322 403 403 TRP TRP A . n 
A 1 323 SER 323 404 404 SER SER A . n 
A 1 324 GLY 324 405 405 GLY GLY A . n 
A 1 325 TYR 325 406 406 TYR TYR A . n 
A 1 326 SER 326 407 407 SER SER A . n 
A 1 327 GLY 327 408 408 GLY GLY A . n 
A 1 328 ALA 328 409 409 ALA ALA A . n 
A 1 329 PHE 329 410 410 PHE PHE A . n 
A 1 330 ILE 330 411 411 ILE ILE A . n 
A 1 331 ASP 331 412 412 ASP ASP A . n 
A 1 332 TYR 332 413 413 TYR TYR A . n 
A 1 333 TRP 333 414 414 TRP TRP A . n 
A 1 334 ALA 334 415 415 ALA ALA A . n 
A 1 335 ASN 335 416 416 ASN ASN A . n 
A 1 336 LYS 336 417 417 LYS LYS A . n 
A 1 337 GLU 337 418 418 GLU GLU A . n 
A 1 338 CYS 338 419 419 CYS CYS A . n 
A 1 339 PHE 339 420 420 PHE PHE A . n 
A 1 340 ASN 340 421 421 ASN ASN A . n 
A 1 341 PRO 341 422 422 PRO PRO A . n 
A 1 342 CYS 342 423 423 CYS CYS A . n 
A 1 343 PHE 343 424 424 PHE PHE A . n 
A 1 344 TYR 344 425 425 TYR TYR A . n 
A 1 345 VAL 345 426 426 VAL VAL A . n 
A 1 346 GLU 346 427 427 GLU GLU A . n 
A 1 347 LEU 347 428 428 LEU LEU A . n 
A 1 348 ILE 348 429 ?   ?   ?   A . n 
A 1 349 ARG 349 430 ?   ?   ?   A . n 
A 1 350 GLY 350 431 ?   ?   ?   A . n 
A 1 351 ARG 351 432 ?   ?   ?   A . n 
A 1 352 PRO 352 433 ?   ?   ?   A . n 
A 1 353 LYS 353 434 ?   ?   ?   A . n 
A 1 354 GLU 354 435 ?   ?   ?   A . n 
A 1 355 ILE 355 436 ?   ?   ?   A . n 
A 1 356 ASP 356 437 ?   ?   ?   A . n 
A 1 357 VAL 357 438 ?   ?   ?   A . n 
A 1 358 LEU 358 439 ?   ?   ?   A . n 
A 1 359 TRP 359 440 ?   ?   ?   A . n 
A 1 360 ALA 360 441 ?   ?   ?   A . n 
A 1 361 SER 361 442 ?   ?   ?   A . n 
A 1 362 ASN 362 443 443 ASN ASN A . n 
A 1 363 SER 363 444 444 SER SER A . n 
A 1 364 MET 364 445 445 MET MET A . n 
A 1 365 VAL 365 446 446 VAL VAL A . n 
A 1 366 ALA 366 447 447 ALA ALA A . n 
A 1 367 LEU 367 448 448 LEU LEU A . n 
A 1 368 CYS 368 449 449 CYS CYS A . n 
A 1 369 GLY 369 450 450 GLY GLY A . n 
A 1 370 SER 370 451 451 SER SER A . n 
A 1 371 ARG 371 452 452 ARG ARG A . n 
A 1 372 GLU 372 453 453 GLU GLU A . n 
A 1 373 ARG 373 454 454 ARG ARG A . n 
A 1 374 LEU 374 455 455 LEU LEU A . n 
A 1 375 GLY 375 456 456 GLY GLY A . n 
A 1 376 SER 376 457 457 SER SER A . n 
A 1 377 TRP 377 458 458 TRP TRP A . n 
A 1 378 SER 378 459 459 SER SER A . n 
A 1 379 TRP 379 460 460 TRP TRP A . n 
B 2 1   GLN 1   1   ?   ?   ?   B . n 
B 2 2   SER 2   2   2   SER SER B . n 
B 2 3   VAL 3   3   3   VAL VAL B . n 
B 2 4   LEU 4   4   4   LEU LEU B . n 
B 2 5   THR 5   5   5   THR THR B . n 
B 2 6   GLN 6   6   6   GLN GLN B . n 
B 2 7   PRO 7   7   7   PRO PRO B . n 
B 2 8   ALA 8   8   8   ALA ALA B . n 
B 2 9   SER 9   9   9   SER SER B . n 
B 2 10  VAL 10  10  10  VAL VAL B . n 
B 2 11  SER 11  11  11  SER SER B . n 
B 2 12  GLY 12  12  12  GLY GLY B . n 
B 2 13  SER 13  13  13  SER SER B . n 
B 2 14  PRO 14  14  14  PRO PRO B . n 
B 2 15  GLY 15  15  15  GLY GLY B . n 
B 2 16  GLN 16  16  16  GLN GLN B . n 
B 2 17  SER 17  17  17  SER SER B . n 
B 2 18  ILE 18  18  18  ILE ILE B . n 
B 2 19  THR 19  19  19  THR THR B . n 
B 2 20  ILE 20  20  20  ILE ILE B . n 
B 2 21  SER 21  21  21  SER SER B . n 
B 2 22  CYS 22  22  22  CYS CYS B . n 
B 2 23  THR 23  23  23  THR THR B . n 
B 2 24  GLY 24  24  24  GLY GLY B . n 
B 2 25  THR 25  25  25  THR THR B . n 
B 2 26  SER 26  26  26  SER SER B . n 
B 2 27  SER 27  27  27  SER SER B . n 
B 2 28  ASP 28  28  28  ASP ASP B . n 
B 2 29  VAL 29  29  29  VAL VAL B . n 
B 2 30  GLY 30  30  30  GLY GLY B . n 
B 2 31  GLY 31  31  31  GLY GLY B . n 
B 2 32  TYR 32  32  32  TYR TYR B . n 
B 2 33  ASN 33  33  33  ASN ASN B . n 
B 2 34  TYR 34  34  34  TYR TYR B . n 
B 2 35  VAL 35  35  35  VAL VAL B . n 
B 2 36  SER 36  36  36  SER SER B . n 
B 2 37  TRP 37  37  37  TRP TRP B . n 
B 2 38  TYR 38  38  38  TYR TYR B . n 
B 2 39  GLN 39  39  39  GLN GLN B . n 
B 2 40  GLN 40  40  40  GLN GLN B . n 
B 2 41  HIS 41  41  41  HIS HIS B . n 
B 2 42  PRO 42  42  42  PRO PRO B . n 
B 2 43  GLY 43  43  43  GLY GLY B . n 
B 2 44  LYS 44  44  44  LYS LYS B . n 
B 2 45  ALA 45  45  45  ALA ALA B . n 
B 2 46  PRO 46  46  46  PRO PRO B . n 
B 2 47  LYS 47  47  47  LYS LYS B . n 
B 2 48  LEU 48  48  48  LEU LEU B . n 
B 2 49  MET 49  49  49  MET MET B . n 
B 2 50  ILE 50  50  50  ILE ILE B . n 
B 2 51  TYR 51  51  51  TYR TYR B . n 
B 2 52  ASP 52  52  52  ASP ASP B . n 
B 2 53  VAL 53  53  53  VAL VAL B . n 
B 2 54  SER 54  54  54  SER SER B . n 
B 2 55  LYS 55  55  55  LYS LYS B . n 
B 2 56  ARG 56  56  56  ARG ARG B . n 
B 2 57  PRO 57  57  57  PRO PRO B . n 
B 2 58  SER 58  58  58  SER SER B . n 
B 2 59  GLY 59  59  59  GLY GLY B . n 
B 2 60  VAL 60  60  60  VAL VAL B . n 
B 2 61  SER 61  61  61  SER SER B . n 
B 2 62  ASN 62  62  62  ASN ASN B . n 
B 2 63  ARG 63  63  63  ARG ARG B . n 
B 2 64  PHE 64  64  64  PHE PHE B . n 
B 2 65  SER 65  65  65  SER SER B . n 
B 2 66  GLY 66  66  66  GLY GLY B . n 
B 2 67  SER 67  67  67  SER SER B . n 
B 2 68  LYS 68  68  68  LYS LYS B . n 
B 2 69  SER 69  69  69  SER SER B . n 
B 2 70  GLY 70  70  70  GLY GLY B . n 
B 2 71  ASN 71  71  71  ASN ASN B . n 
B 2 72  THR 72  72  72  THR THR B . n 
B 2 73  ALA 73  73  73  ALA ALA B . n 
B 2 74  SER 74  74  74  SER SER B . n 
B 2 75  LEU 75  75  75  LEU LEU B . n 
B 2 76  THR 76  76  76  THR THR B . n 
B 2 77  ILE 77  77  77  ILE ILE B . n 
B 2 78  SER 78  78  78  SER SER B . n 
B 2 79  GLY 79  79  79  GLY GLY B . n 
B 2 80  LEU 80  80  80  LEU LEU B . n 
B 2 81  GLN 81  81  81  GLN GLN B . n 
B 2 82  ALA 82  82  82  ALA ALA B . n 
B 2 83  GLU 83  83  83  GLU GLU B . n 
B 2 84  ASP 84  84  84  ASP ASP B . n 
B 2 85  GLU 85  85  85  GLU GLU B . n 
B 2 86  ALA 86  86  86  ALA ALA B . n 
B 2 87  ASP 87  87  87  ASP ASP B . n 
B 2 88  TYR 88  88  88  TYR TYR B . n 
B 2 89  TYR 89  89  89  TYR TYR B . n 
B 2 90  CYS 90  90  90  CYS CYS B . n 
B 2 91  SER 91  91  91  SER SER B . n 
B 2 92  SER 92  92  92  SER SER B . n 
B 2 93  TYR 93  93  93  TYR TYR B . n 
B 2 94  THR 94  94  94  THR THR B . n 
B 2 95  SER 95  95  95  SER SER B . n 
B 2 96  SER 96  96  96  SER SER B . n 
B 2 97  SER 97  97  97  SER SER B . n 
B 2 98  THR 98  98  98  THR THR B . n 
B 2 99  TRP 99  99  99  TRP TRP B . n 
B 2 100 VAL 100 100 100 VAL VAL B . n 
B 2 101 PHE 101 101 101 PHE PHE B . n 
B 2 102 GLY 102 102 102 GLY GLY B . n 
B 2 103 GLY 103 103 103 GLY GLY B . n 
B 2 104 GLY 104 104 104 GLY GLY B . n 
B 2 105 THR 105 105 105 THR THR B . n 
B 2 106 LYS 106 106 106 LYS LYS B . n 
B 2 107 LEU 107 107 107 LEU LEU B . n 
B 2 108 THR 108 108 108 THR THR B . n 
B 2 109 VAL 109 109 109 VAL VAL B . n 
B 2 110 LEU 110 110 110 LEU LEU B . n 
B 2 111 GLY 111 111 111 GLY GLY B . n 
B 2 112 GLN 112 112 112 GLN GLN B . n 
B 2 113 PRO 113 113 113 PRO PRO B . n 
B 2 114 LYS 114 114 ?   ?   ?   B . n 
B 2 115 ALA 115 115 ?   ?   ?   B . n 
B 2 116 ALA 116 116 ?   ?   ?   B . n 
B 2 117 PRO 117 117 ?   ?   ?   B . n 
B 2 118 SER 118 118 ?   ?   ?   B . n 
B 2 119 VAL 119 119 ?   ?   ?   B . n 
B 2 120 THR 120 120 ?   ?   ?   B . n 
B 2 121 LEU 121 121 ?   ?   ?   B . n 
B 2 122 PHE 122 122 ?   ?   ?   B . n 
B 2 123 PRO 123 123 ?   ?   ?   B . n 
B 2 124 PRO 124 124 ?   ?   ?   B . n 
B 2 125 SER 125 125 ?   ?   ?   B . n 
B 2 126 SER 126 126 ?   ?   ?   B . n 
B 2 127 GLU 127 127 ?   ?   ?   B . n 
B 2 128 GLU 128 128 ?   ?   ?   B . n 
B 2 129 LEU 129 129 ?   ?   ?   B . n 
B 2 130 GLN 130 130 ?   ?   ?   B . n 
B 2 131 ALA 131 131 ?   ?   ?   B . n 
B 2 132 ASN 132 132 ?   ?   ?   B . n 
B 2 133 LYS 133 133 ?   ?   ?   B . n 
B 2 134 ALA 134 134 ?   ?   ?   B . n 
B 2 135 THR 135 135 ?   ?   ?   B . n 
B 2 136 LEU 136 136 ?   ?   ?   B . n 
B 2 137 VAL 137 137 ?   ?   ?   B . n 
B 2 138 CYS 138 138 ?   ?   ?   B . n 
B 2 139 LEU 139 139 ?   ?   ?   B . n 
B 2 140 ILE 140 140 ?   ?   ?   B . n 
B 2 141 SER 141 141 ?   ?   ?   B . n 
B 2 142 ASP 142 142 ?   ?   ?   B . n 
B 2 143 PHE 143 143 ?   ?   ?   B . n 
B 2 144 TYR 144 144 ?   ?   ?   B . n 
B 2 145 PRO 145 145 ?   ?   ?   B . n 
B 2 146 GLY 146 146 ?   ?   ?   B . n 
B 2 147 ALA 147 147 ?   ?   ?   B . n 
B 2 148 VAL 148 148 ?   ?   ?   B . n 
B 2 149 THR 149 149 ?   ?   ?   B . n 
B 2 150 VAL 150 150 ?   ?   ?   B . n 
B 2 151 ALA 151 151 ?   ?   ?   B . n 
B 2 152 TRP 152 152 ?   ?   ?   B . n 
B 2 153 LYS 153 153 ?   ?   ?   B . n 
B 2 154 ALA 154 154 ?   ?   ?   B . n 
B 2 155 ASP 155 155 ?   ?   ?   B . n 
B 2 156 SER 156 156 ?   ?   ?   B . n 
B 2 157 SER 157 157 ?   ?   ?   B . n 
B 2 158 PRO 158 158 ?   ?   ?   B . n 
B 2 159 VAL 159 159 ?   ?   ?   B . n 
B 2 160 LYS 160 160 ?   ?   ?   B . n 
B 2 161 ALA 161 161 ?   ?   ?   B . n 
B 2 162 GLY 162 162 ?   ?   ?   B . n 
B 2 163 VAL 163 163 ?   ?   ?   B . n 
B 2 164 GLU 164 164 ?   ?   ?   B . n 
B 2 165 THR 165 165 ?   ?   ?   B . n 
B 2 166 THR 166 166 ?   ?   ?   B . n 
B 2 167 THR 167 167 ?   ?   ?   B . n 
B 2 168 PRO 168 168 ?   ?   ?   B . n 
B 2 169 SER 169 169 ?   ?   ?   B . n 
B 2 170 LYS 170 170 ?   ?   ?   B . n 
B 2 171 GLN 171 171 ?   ?   ?   B . n 
B 2 172 SER 172 172 ?   ?   ?   B . n 
B 2 173 ASN 173 173 ?   ?   ?   B . n 
B 2 174 ASN 174 174 ?   ?   ?   B . n 
B 2 175 LYS 175 175 ?   ?   ?   B . n 
B 2 176 TYR 176 176 ?   ?   ?   B . n 
B 2 177 ALA 177 177 ?   ?   ?   B . n 
B 2 178 ALA 178 178 ?   ?   ?   B . n 
B 2 179 SER 179 179 ?   ?   ?   B . n 
B 2 180 SER 180 180 ?   ?   ?   B . n 
B 2 181 TYR 181 181 ?   ?   ?   B . n 
B 2 182 LEU 182 182 ?   ?   ?   B . n 
B 2 183 SER 183 183 ?   ?   ?   B . n 
B 2 184 LEU 184 184 ?   ?   ?   B . n 
B 2 185 THR 185 185 ?   ?   ?   B . n 
B 2 186 PRO 186 186 ?   ?   ?   B . n 
B 2 187 GLU 187 187 ?   ?   ?   B . n 
B 2 188 GLN 188 188 ?   ?   ?   B . n 
B 2 189 TRP 189 189 ?   ?   ?   B . n 
B 2 190 LYS 190 190 ?   ?   ?   B . n 
B 2 191 SER 191 191 ?   ?   ?   B . n 
B 2 192 HIS 192 192 ?   ?   ?   B . n 
B 2 193 ARG 193 193 ?   ?   ?   B . n 
B 2 194 SER 194 194 ?   ?   ?   B . n 
B 2 195 TYR 195 195 ?   ?   ?   B . n 
B 2 196 SER 196 196 ?   ?   ?   B . n 
B 2 197 CYS 197 197 ?   ?   ?   B . n 
B 2 198 GLN 198 198 ?   ?   ?   B . n 
B 2 199 VAL 199 199 ?   ?   ?   B . n 
B 2 200 THR 200 200 ?   ?   ?   B . n 
B 2 201 HIS 201 201 ?   ?   ?   B . n 
B 2 202 GLU 202 202 ?   ?   ?   B . n 
B 2 203 GLY 203 203 ?   ?   ?   B . n 
B 2 204 SER 204 204 ?   ?   ?   B . n 
B 2 205 THR 205 205 ?   ?   ?   B . n 
B 2 206 VAL 206 206 ?   ?   ?   B . n 
B 2 207 GLU 207 207 ?   ?   ?   B . n 
B 2 208 LYS 208 208 ?   ?   ?   B . n 
B 2 209 THR 209 209 ?   ?   ?   B . n 
B 2 210 VAL 210 210 ?   ?   ?   B . n 
B 2 211 ALA 211 211 ?   ?   ?   B . n 
B 2 212 PRO 212 212 ?   ?   ?   B . n 
B 2 213 THR 213 213 ?   ?   ?   B . n 
B 2 214 GLU 214 214 ?   ?   ?   B . n 
B 2 215 CYS 215 215 ?   ?   ?   B . n 
B 2 216 SER 216 216 ?   ?   ?   B . n 
C 3 1   GLN 1   1   1   GLN GLN C . n 
C 3 2   VAL 2   2   2   VAL VAL C . n 
C 3 3   GLN 3   3   3   GLN GLN C . n 
C 3 4   LEU 4   4   4   LEU LEU C . n 
C 3 5   VAL 5   5   5   VAL VAL C . n 
C 3 6   GLN 6   6   6   GLN GLN C . n 
C 3 7   SER 7   7   7   SER SER C . n 
C 3 8   GLY 8   8   8   GLY GLY C . n 
C 3 9   ALA 9   9   9   ALA ALA C . n 
C 3 10  GLU 10  10  10  GLU GLU C . n 
C 3 11  VAL 11  11  11  VAL VAL C . n 
C 3 12  LYS 12  12  12  LYS LYS C . n 
C 3 13  LYS 13  13  13  LYS LYS C . n 
C 3 14  PRO 14  14  14  PRO PRO C . n 
C 3 15  GLY 15  15  15  GLY GLY C . n 
C 3 16  SER 16  16  16  SER SER C . n 
C 3 17  SER 17  17  17  SER SER C . n 
C 3 18  VAL 18  18  18  VAL VAL C . n 
C 3 19  LYS 19  19  19  LYS LYS C . n 
C 3 20  VAL 20  20  20  VAL VAL C . n 
C 3 21  SER 21  21  21  SER SER C . n 
C 3 22  CYS 22  22  22  CYS CYS C . n 
C 3 23  LYS 23  23  23  LYS LYS C . n 
C 3 24  ALA 24  24  24  ALA ALA C . n 
C 3 25  SER 25  25  25  SER SER C . n 
C 3 26  GLY 26  26  26  GLY GLY C . n 
C 3 27  GLY 27  27  27  GLY GLY C . n 
C 3 28  THR 28  28  28  THR THR C . n 
C 3 29  PHE 29  29  29  PHE PHE C . n 
C 3 30  SER 30  30  30  SER SER C . n 
C 3 31  SER 31  31  31  SER SER C . n 
C 3 32  TYR 32  32  32  TYR TYR C . n 
C 3 33  ALA 33  33  33  ALA ALA C . n 
C 3 34  ILE 34  34  34  ILE ILE C . n 
C 3 35  SER 35  35  35  SER SER C . n 
C 3 36  TRP 36  36  36  TRP TRP C . n 
C 3 37  VAL 37  37  37  VAL VAL C . n 
C 3 38  ARG 38  38  38  ARG ARG C . n 
C 3 39  GLN 39  39  39  GLN GLN C . n 
C 3 40  ALA 40  40  40  ALA ALA C . n 
C 3 41  PRO 41  41  41  PRO PRO C . n 
C 3 42  GLY 42  42  42  GLY GLY C . n 
C 3 43  GLN 43  43  43  GLN GLN C . n 
C 3 44  GLY 44  44  44  GLY GLY C . n 
C 3 45  LEU 45  45  45  LEU LEU C . n 
C 3 46  GLU 46  46  46  GLU GLU C . n 
C 3 47  TRP 47  47  47  TRP TRP C . n 
C 3 48  MET 48  48  48  MET MET C . n 
C 3 49  GLY 49  49  49  GLY GLY C . n 
C 3 50  GLY 50  50  50  GLY GLY C . n 
C 3 51  ILE 51  51  51  ILE ILE C . n 
C 3 52  ILE 52  52  52  ILE ILE C . n 
C 3 53  PRO 53  53  53  PRO PRO C . n 
C 3 54  ILE 54  54  54  ILE ILE C . n 
C 3 55  PHE 55  55  55  PHE PHE C . n 
C 3 56  GLY 56  56  56  GLY GLY C . n 
C 3 57  THR 57  57  57  THR THR C . n 
C 3 58  ALA 58  58  58  ALA ALA C . n 
C 3 59  ASN 59  59  59  ASN ASN C . n 
C 3 60  TYR 60  60  60  TYR TYR C . n 
C 3 61  ALA 61  61  61  ALA ALA C . n 
C 3 62  GLN 62  62  62  GLN GLN C . n 
C 3 63  LYS 63  63  63  LYS LYS C . n 
C 3 64  PHE 64  64  64  PHE PHE C . n 
C 3 65  GLN 65  65  65  GLN GLN C . n 
C 3 66  GLY 66  66  66  GLY GLY C . n 
C 3 67  ARG 67  67  67  ARG ARG C . n 
C 3 68  VAL 68  68  68  VAL VAL C . n 
C 3 69  THR 69  69  69  THR THR C . n 
C 3 70  ILE 70  70  70  ILE ILE C . n 
C 3 71  THR 71  71  71  THR THR C . n 
C 3 72  ALA 72  72  72  ALA ALA C . n 
C 3 73  ASP 73  73  73  ASP ASP C . n 
C 3 74  GLU 74  74  74  GLU GLU C . n 
C 3 75  SER 75  75  75  SER SER C . n 
C 3 76  THR 76  76  76  THR THR C . n 
C 3 77  SER 77  77  77  SER SER C . n 
C 3 78  THR 78  78  78  THR THR C . n 
C 3 79  ALA 79  79  79  ALA ALA C . n 
C 3 80  TYR 80  80  80  TYR TYR C . n 
C 3 81  MET 81  81  81  MET MET C . n 
C 3 82  GLU 82  82  82  GLU GLU C . n 
C 3 83  LEU 83  83  83  LEU LEU C . n 
C 3 84  SER 84  84  84  SER SER C . n 
C 3 85  SER 85  85  85  SER SER C . n 
C 3 86  LEU 86  86  86  LEU LEU C . n 
C 3 87  ARG 87  87  87  ARG ARG C . n 
C 3 88  SER 88  88  88  SER SER C . n 
C 3 89  GLU 89  89  89  GLU GLU C . n 
C 3 90  ASP 90  90  90  ASP ASP C . n 
C 3 91  THR 91  91  91  THR THR C . n 
C 3 92  ALA 92  92  92  ALA ALA C . n 
C 3 93  VAL 93  93  93  VAL VAL C . n 
C 3 94  TYR 94  94  94  TYR TYR C . n 
C 3 95  TYR 95  95  95  TYR TYR C . n 
C 3 96  CYS 96  96  96  CYS CYS C . n 
C 3 97  ALA 97  97  97  ALA ALA C . n 
C 3 98  ARG 98  98  98  ARG ARG C . n 
C 3 99  GLY 99  99  99  GLY GLY C . n 
C 3 100 GLN 100 100 100 GLN GLN C . n 
C 3 101 LEU 101 101 101 LEU LEU C . n 
C 3 102 ARG 102 102 102 ARG ARG C . n 
C 3 103 TYR 103 103 103 TYR TYR C . n 
C 3 104 PHE 104 104 104 PHE PHE C . n 
C 3 105 ASP 105 105 105 ASP ASP C . n 
C 3 106 TRP 106 106 106 TRP TRP C . n 
C 3 107 PRO 107 107 107 PRO PRO C . n 
C 3 108 THR 108 108 108 THR THR C . n 
C 3 109 ILE 109 109 109 ILE ILE C . n 
C 3 110 PRO 110 110 110 PRO PRO C . n 
C 3 111 SER 111 111 111 SER SER C . n 
C 3 112 SER 112 112 112 SER SER C . n 
C 3 113 TYR 113 113 113 TYR TYR C . n 
C 3 114 TYR 114 114 114 TYR TYR C . n 
C 3 115 GLY 115 115 115 GLY GLY C . n 
C 3 116 MET 116 116 116 MET MET C . n 
C 3 117 ASP 117 117 117 ASP ASP C . n 
C 3 118 VAL 118 118 118 VAL VAL C . n 
C 3 119 TRP 119 119 119 TRP TRP C . n 
C 3 120 GLY 120 120 120 GLY GLY C . n 
C 3 121 GLN 121 121 121 GLN GLN C . n 
C 3 122 GLY 122 122 122 GLY GLY C . n 
C 3 123 THR 123 123 123 THR THR C . n 
C 3 124 THR 124 124 124 THR THR C . n 
C 3 125 VAL 125 125 125 VAL VAL C . n 
C 3 126 THR 126 126 126 THR THR C . n 
C 3 127 VAL 127 127 127 VAL VAL C . n 
C 3 128 SER 128 128 128 SER SER C . n 
C 3 129 SER 129 129 129 SER SER C . n 
C 3 130 ALA 130 130 130 ALA ALA C . n 
C 3 131 SER 131 131 ?   ?   ?   C . n 
C 3 132 THR 132 132 ?   ?   ?   C . n 
C 3 133 LYS 133 133 ?   ?   ?   C . n 
C 3 134 GLY 134 134 ?   ?   ?   C . n 
C 3 135 PRO 135 135 ?   ?   ?   C . n 
C 3 136 SER 136 136 ?   ?   ?   C . n 
C 3 137 VAL 137 137 ?   ?   ?   C . n 
C 3 138 PHE 138 138 ?   ?   ?   C . n 
C 3 139 PRO 139 139 ?   ?   ?   C . n 
C 3 140 LEU 140 140 ?   ?   ?   C . n 
C 3 141 ALA 141 141 ?   ?   ?   C . n 
C 3 142 PRO 142 142 ?   ?   ?   C . n 
C 3 143 SER 143 143 ?   ?   ?   C . n 
C 3 144 SER 144 144 ?   ?   ?   C . n 
C 3 145 LYS 145 145 ?   ?   ?   C . n 
C 3 146 SER 146 146 ?   ?   ?   C . n 
C 3 147 THR 147 147 ?   ?   ?   C . n 
C 3 148 SER 148 148 ?   ?   ?   C . n 
C 3 149 GLY 149 149 ?   ?   ?   C . n 
C 3 150 GLY 150 150 ?   ?   ?   C . n 
C 3 151 THR 151 151 ?   ?   ?   C . n 
C 3 152 ALA 152 152 ?   ?   ?   C . n 
C 3 153 ALA 153 153 ?   ?   ?   C . n 
C 3 154 LEU 154 154 ?   ?   ?   C . n 
C 3 155 GLY 155 155 ?   ?   ?   C . n 
C 3 156 CYS 156 156 ?   ?   ?   C . n 
C 3 157 LEU 157 157 ?   ?   ?   C . n 
C 3 158 VAL 158 158 ?   ?   ?   C . n 
C 3 159 LYS 159 159 ?   ?   ?   C . n 
C 3 160 ASP 160 160 ?   ?   ?   C . n 
C 3 161 TYR 161 161 ?   ?   ?   C . n 
C 3 162 PHE 162 162 ?   ?   ?   C . n 
C 3 163 PRO 163 163 ?   ?   ?   C . n 
C 3 164 GLU 164 164 ?   ?   ?   C . n 
C 3 165 PRO 165 165 ?   ?   ?   C . n 
C 3 166 VAL 166 166 ?   ?   ?   C . n 
C 3 167 THR 167 167 ?   ?   ?   C . n 
C 3 168 VAL 168 168 ?   ?   ?   C . n 
C 3 169 SER 169 169 ?   ?   ?   C . n 
C 3 170 TRP 170 170 ?   ?   ?   C . n 
C 3 171 ASN 171 171 ?   ?   ?   C . n 
C 3 172 SER 172 172 ?   ?   ?   C . n 
C 3 173 GLY 173 173 ?   ?   ?   C . n 
C 3 174 ALA 174 174 ?   ?   ?   C . n 
C 3 175 LEU 175 175 ?   ?   ?   C . n 
C 3 176 THR 176 176 ?   ?   ?   C . n 
C 3 177 SER 177 177 ?   ?   ?   C . n 
C 3 178 GLY 178 178 ?   ?   ?   C . n 
C 3 179 VAL 179 179 ?   ?   ?   C . n 
C 3 180 HIS 180 180 ?   ?   ?   C . n 
C 3 181 THR 181 181 ?   ?   ?   C . n 
C 3 182 PHE 182 182 ?   ?   ?   C . n 
C 3 183 PRO 183 183 ?   ?   ?   C . n 
C 3 184 ALA 184 184 ?   ?   ?   C . n 
C 3 185 VAL 185 185 ?   ?   ?   C . n 
C 3 186 LEU 186 186 ?   ?   ?   C . n 
C 3 187 GLN 187 187 ?   ?   ?   C . n 
C 3 188 SER 188 188 ?   ?   ?   C . n 
C 3 189 SER 189 189 ?   ?   ?   C . n 
C 3 190 GLY 190 190 ?   ?   ?   C . n 
C 3 191 LEU 191 191 ?   ?   ?   C . n 
C 3 192 TYR 192 192 ?   ?   ?   C . n 
C 3 193 SER 193 193 ?   ?   ?   C . n 
C 3 194 LEU 194 194 ?   ?   ?   C . n 
C 3 195 SER 195 195 ?   ?   ?   C . n 
C 3 196 SER 196 196 ?   ?   ?   C . n 
C 3 197 VAL 197 197 ?   ?   ?   C . n 
C 3 198 VAL 198 198 ?   ?   ?   C . n 
C 3 199 THR 199 199 ?   ?   ?   C . n 
C 3 200 VAL 200 200 ?   ?   ?   C . n 
C 3 201 PRO 201 201 ?   ?   ?   C . n 
C 3 202 SER 202 202 ?   ?   ?   C . n 
C 3 203 SER 203 203 ?   ?   ?   C . n 
C 3 204 SER 204 204 ?   ?   ?   C . n 
C 3 205 LEU 205 205 ?   ?   ?   C . n 
C 3 206 GLY 206 206 ?   ?   ?   C . n 
C 3 207 THR 207 207 ?   ?   ?   C . n 
C 3 208 GLN 208 208 ?   ?   ?   C . n 
C 3 209 THR 209 209 ?   ?   ?   C . n 
C 3 210 TYR 210 210 ?   ?   ?   C . n 
C 3 211 ILE 211 211 ?   ?   ?   C . n 
C 3 212 CYS 212 212 ?   ?   ?   C . n 
C 3 213 ASN 213 213 ?   ?   ?   C . n 
C 3 214 VAL 214 214 ?   ?   ?   C . n 
C 3 215 ASN 215 215 ?   ?   ?   C . n 
C 3 216 HIS 216 216 ?   ?   ?   C . n 
C 3 217 LYS 217 217 ?   ?   ?   C . n 
C 3 218 PRO 218 218 ?   ?   ?   C . n 
C 3 219 SER 219 219 ?   ?   ?   C . n 
C 3 220 ASN 220 220 ?   ?   ?   C . n 
C 3 221 THR 221 221 ?   ?   ?   C . n 
C 3 222 LYS 222 222 ?   ?   ?   C . n 
C 3 223 VAL 223 223 ?   ?   ?   C . n 
C 3 224 ASP 224 224 ?   ?   ?   C . n 
C 3 225 LYS 225 225 ?   ?   ?   C . n 
C 3 226 ARG 226 226 ?   ?   ?   C . n 
C 3 227 VAL 227 227 ?   ?   ?   C . n 
C 3 228 GLU 228 228 ?   ?   ?   C . n 
C 3 229 PRO 229 229 ?   ?   ?   C . n 
C 3 230 LYS 230 230 ?   ?   ?   C . n 
C 3 231 SER 231 231 ?   ?   ?   C . n 
C 3 232 CYS 232 232 ?   ?   ?   C . n 
C 3 233 ASP 233 233 ?   ?   ?   C . n 
C 3 234 LYS 234 234 ?   ?   ?   C . n 
C 3 235 THR 235 235 ?   ?   ?   C . n 
C 3 236 HIS 236 236 ?   ?   ?   C . n 
D 4 1   GLU 1   1   1   GLU GLU E . n 
D 4 2   VAL 2   2   2   VAL VAL E . n 
D 4 3   GLN 3   3   3   GLN GLN E . n 
D 4 4   LEU 4   4   4   LEU LEU E . n 
D 4 5   VAL 5   5   5   VAL VAL E . n 
D 4 6   GLU 6   6   6   GLU GLU E . n 
D 4 7   SER 7   7   7   SER SER E . n 
D 4 8   GLY 8   8   8   GLY GLY E . n 
D 4 9   GLY 9   9   9   GLY GLY E . n 
D 4 10  ARG 10  10  10  ARG ARG E . n 
D 4 11  ALA 11  11  11  ALA ALA E . n 
D 4 12  LEU 12  12  12  LEU LEU E . n 
D 4 13  ARG 13  13  13  ARG ARG E . n 
D 4 14  PRO 14  14  14  PRO PRO E . n 
D 4 15  GLY 15  15  15  GLY GLY E . n 
D 4 16  GLY 16  16  16  GLY GLY E . n 
D 4 17  SER 17  17  17  SER SER E . n 
D 4 18  LEU 18  18  18  LEU LEU E . n 
D 4 19  ARG 19  19  19  ARG ARG E . n 
D 4 20  LEU 20  20  20  LEU LEU E . n 
D 4 21  SER 21  21  21  SER SER E . n 
D 4 22  CYS 22  22  22  CYS CYS E . n 
D 4 23  ALA 23  23  23  ALA ALA E . n 
D 4 24  ALA 24  24  24  ALA ALA E . n 
D 4 25  SER 25  25  25  SER SER E . n 
D 4 26  GLY 26  26  26  GLY GLY E . n 
D 4 27  PHE 27  27  27  PHE PHE E . n 
D 4 28  LYS 28  28  28  LYS LYS E . n 
D 4 29  PHE 29  29  29  PHE PHE E . n 
D 4 30  ASP 30  30  30  ASP ASP E . n 
D 4 31  ASP 31  31  31  ASP ASP E . n 
D 4 32  TYR 32  32  32  TYR TYR E . n 
D 4 33  ALA 33  33  33  ALA ALA E . n 
D 4 34  MET 34  34  34  MET MET E . n 
D 4 35  SER 35  35  35  SER SER E . n 
D 4 36  TRP 36  36  36  TRP TRP E . n 
D 4 37  VAL 37  37  37  VAL VAL E . n 
D 4 38  ARG 38  38  38  ARG ARG E . n 
D 4 39  GLN 39  39  39  GLN GLN E . n 
D 4 40  VAL 40  40  40  VAL VAL E . n 
D 4 41  PRO 41  41  41  PRO PRO E . n 
D 4 42  GLY 42  42  42  GLY GLY E . n 
D 4 43  LYS 43  43  43  LYS LYS E . n 
D 4 44  GLY 44  44  44  GLY GLY E . n 
D 4 45  LEU 45  45  45  LEU LEU E . n 
D 4 46  GLU 46  46  46  GLU GLU E . n 
D 4 47  PHE 47  47  47  PHE PHE E . n 
D 4 48  VAL 48  48  48  VAL VAL E . n 
D 4 49  SER 49  49  49  SER SER E . n 
D 4 50  GLY 50  50  50  GLY GLY E . n 
D 4 51  LEU 51  51  51  LEU LEU E . n 
D 4 52  ASN 52  52  52  ASN ASN E . n 
D 4 53  TRP 53  52  52  TRP TRP E A n 
D 4 54  ASN 54  53  53  ASN ASN E . n 
D 4 55  GLY 55  54  54  GLY GLY E . n 
D 4 56  ASP 56  55  55  ASP ASP E . n 
D 4 57  ILE 57  56  56  ILE ILE E . n 
D 4 58  THR 58  57  57  THR THR E . n 
D 4 59  ALA 59  58  58  ALA ALA E . n 
D 4 60  TYR 60  59  59  TYR TYR E . n 
D 4 61  THR 61  60  60  THR THR E . n 
D 4 62  ASP 62  61  61  ASP ASP E . n 
D 4 63  SER 63  62  62  SER SER E . n 
D 4 64  VAL 64  63  63  VAL VAL E . n 
D 4 65  LYS 65  64  64  LYS LYS E . n 
D 4 66  GLY 66  65  65  GLY GLY E . n 
D 4 67  ARG 67  66  66  ARG ARG E . n 
D 4 68  PHE 68  67  67  PHE PHE E . n 
D 4 69  THR 69  68  68  THR THR E . n 
D 4 70  VAL 70  69  69  VAL VAL E . n 
D 4 71  SER 71  70  70  SER SER E . n 
D 4 72  ARG 72  71  71  ARG ARG E . n 
D 4 73  ASP 73  72  72  ASP ASP E . n 
D 4 74  ASN 74  73  73  ASN ASN E . n 
D 4 75  ALA 75  74  74  ALA ALA E . n 
D 4 76  LYS 76  75  75  LYS LYS E . n 
D 4 77  ASN 77  76  76  ASN ASN E . n 
D 4 78  SER 78  77  77  SER SER E . n 
D 4 79  LEU 79  78  78  LEU LEU E . n 
D 4 80  TYR 80  79  79  TYR TYR E . n 
D 4 81  LEU 81  80  80  LEU LEU E . n 
D 4 82  HIS 82  81  81  HIS HIS E . n 
D 4 83  ILE 83  82  82  ILE ILE E . n 
D 4 84  ASN 84  82  82  ASN ASN E A n 
D 4 85  SER 85  82  82  SER SER E B n 
D 4 86  PRO 86  82  82  PRO PRO E C n 
D 4 87  LYS 87  83  83  LYS LYS E . n 
D 4 88  PRO 88  84  84  PRO PRO E . n 
D 4 89  GLU 89  85  85  GLU GLU E . n 
D 4 90  ASP 90  86  86  ASP ASP E . n 
D 4 91  THR 91  87  87  THR THR E . n 
D 4 92  ALA 92  88  88  ALA ALA E . n 
D 4 93  LEU 93  89  89  LEU LEU E . n 
D 4 94  TYR 94  90  90  TYR TYR E . n 
D 4 95  TYR 95  91  91  TYR TYR E . n 
D 4 96  CYS 96  92  92  CYS CYS E . n 
D 4 97  ALA 97  93  93  ALA ALA E . n 
D 4 98  ARG 98  94  94  ARG ARG E . n 
D 4 99  THR 99  95  95  THR THR E . n 
D 4 100 SER 100 96  96  SER SER E . n 
D 4 101 SER 101 97  97  SER SER E . n 
D 4 102 TRP 102 98  98  TRP TRP E . n 
D 4 103 GLY 103 99  99  GLY GLY E . n 
D 4 104 ASP 104 100 100 ASP ASP E . n 
D 4 105 TYR 105 100 100 TYR TYR E A n 
D 4 106 THR 106 100 100 THR THR E B n 
D 4 107 ARG 107 100 100 ARG ARG E C n 
D 4 108 GLY 108 100 100 GLY GLY E D n 
D 4 109 PRO 109 100 100 PRO PRO E E n 
D 4 110 GLU 110 100 100 GLU GLU E F n 
D 4 111 PRO 111 100 100 PRO PRO E G n 
D 4 112 LYS 112 100 100 LYS LYS E H n 
D 4 113 ILE 113 100 100 ILE ILE E I n 
D 4 114 THR 114 100 100 THR THR E J n 
D 4 115 TRP 115 100 100 TRP TRP E K n 
D 4 116 TYR 116 100 100 TYR TYR E L n 
D 4 117 PHE 117 100 100 PHE PHE E M n 
D 4 118 ASP 118 101 101 ASP ASP E . n 
D 4 119 LEU 119 102 102 LEU LEU E . n 
D 4 120 TRP 120 103 103 TRP TRP E . n 
D 4 121 GLY 121 104 104 GLY GLY E . n 
D 4 122 ARG 122 105 105 ARG ARG E . n 
D 4 123 GLY 123 106 106 GLY GLY E . n 
D 4 124 THR 124 107 107 THR THR E . n 
D 4 125 LEU 125 108 108 LEU LEU E . n 
D 4 126 VAL 126 109 109 VAL VAL E . n 
D 4 127 THR 127 110 110 THR THR E . n 
D 4 128 VAL 128 111 111 VAL VAL E . n 
D 4 129 SER 129 112 112 SER SER E . n 
D 4 130 SER 130 113 113 SER SER E . n 
D 4 131 ALA 131 114 114 ALA ALA E . n 
D 4 132 SER 132 115 ?   ?   ?   E . n 
D 4 133 THR 133 116 ?   ?   ?   E . n 
D 4 134 LYS 134 117 ?   ?   ?   E . n 
D 4 135 GLY 135 118 ?   ?   ?   E . n 
D 4 136 PRO 136 119 ?   ?   ?   E . n 
D 4 137 SER 137 120 ?   ?   ?   E . n 
D 4 138 VAL 138 121 ?   ?   ?   E . n 
D 4 139 PHE 139 122 ?   ?   ?   E . n 
D 4 140 PRO 140 123 ?   ?   ?   E . n 
D 4 141 LEU 141 124 ?   ?   ?   E . n 
D 4 142 ALA 142 125 ?   ?   ?   E . n 
D 4 143 PRO 143 126 ?   ?   ?   E . n 
D 4 144 SER 144 127 ?   ?   ?   E . n 
D 4 145 SER 145 128 ?   ?   ?   E . n 
D 4 146 LYS 146 129 ?   ?   ?   E . n 
D 4 147 SER 147 130 ?   ?   ?   E . n 
D 4 148 THR 148 131 ?   ?   ?   E . n 
D 4 149 SER 149 132 ?   ?   ?   E . n 
D 4 150 GLY 150 133 ?   ?   ?   E . n 
D 4 151 GLY 151 134 ?   ?   ?   E . n 
D 4 152 THR 152 135 ?   ?   ?   E . n 
D 4 153 ALA 153 136 ?   ?   ?   E . n 
D 4 154 ALA 154 137 ?   ?   ?   E . n 
D 4 155 LEU 155 138 ?   ?   ?   E . n 
D 4 156 GLY 156 139 ?   ?   ?   E . n 
D 4 157 CYS 157 140 ?   ?   ?   E . n 
D 4 158 LEU 158 141 ?   ?   ?   E . n 
D 4 159 VAL 159 142 ?   ?   ?   E . n 
D 4 160 LYS 160 143 ?   ?   ?   E . n 
D 4 161 ASP 161 144 ?   ?   ?   E . n 
D 4 162 TYR 162 145 ?   ?   ?   E . n 
D 4 163 PHE 163 146 ?   ?   ?   E . n 
D 4 164 PRO 164 147 ?   ?   ?   E . n 
D 4 165 GLU 165 148 ?   ?   ?   E . n 
D 4 166 PRO 166 149 ?   ?   ?   E . n 
D 4 167 VAL 167 150 ?   ?   ?   E . n 
D 4 168 THR 168 151 ?   ?   ?   E . n 
D 4 169 VAL 169 152 ?   ?   ?   E . n 
D 4 170 SER 170 153 ?   ?   ?   E . n 
D 4 171 TRP 171 154 ?   ?   ?   E . n 
D 4 172 ASN 172 155 ?   ?   ?   E . n 
D 4 173 SER 173 156 ?   ?   ?   E . n 
D 4 174 GLY 174 157 ?   ?   ?   E . n 
D 4 175 ALA 175 158 ?   ?   ?   E . n 
D 4 176 LEU 176 159 ?   ?   ?   E . n 
D 4 177 THR 177 160 ?   ?   ?   E . n 
D 4 178 SER 178 161 ?   ?   ?   E . n 
D 4 179 GLY 179 162 ?   ?   ?   E . n 
D 4 180 VAL 180 163 ?   ?   ?   E . n 
D 4 181 HIS 181 164 ?   ?   ?   E . n 
D 4 182 THR 182 165 ?   ?   ?   E . n 
D 4 183 PHE 183 166 ?   ?   ?   E . n 
D 4 184 PRO 184 167 ?   ?   ?   E . n 
D 4 185 ALA 185 168 ?   ?   ?   E . n 
D 4 186 VAL 186 169 ?   ?   ?   E . n 
D 4 187 LEU 187 170 ?   ?   ?   E . n 
D 4 188 GLN 188 171 ?   ?   ?   E . n 
D 4 189 SER 189 172 ?   ?   ?   E . n 
D 4 190 SER 190 173 ?   ?   ?   E . n 
D 4 191 GLY 191 174 ?   ?   ?   E . n 
D 4 192 LEU 192 175 ?   ?   ?   E . n 
D 4 193 TYR 193 176 ?   ?   ?   E . n 
D 4 194 SER 194 177 ?   ?   ?   E . n 
D 4 195 LEU 195 178 ?   ?   ?   E . n 
D 4 196 SER 196 179 ?   ?   ?   E . n 
D 4 197 SER 197 180 ?   ?   ?   E . n 
D 4 198 VAL 198 181 ?   ?   ?   E . n 
D 4 199 VAL 199 182 ?   ?   ?   E . n 
D 4 200 THR 200 183 ?   ?   ?   E . n 
D 4 201 VAL 201 184 ?   ?   ?   E . n 
D 4 202 PRO 202 185 ?   ?   ?   E . n 
D 4 203 SER 203 186 ?   ?   ?   E . n 
D 4 204 SER 204 187 ?   ?   ?   E . n 
D 4 205 SER 205 188 ?   ?   ?   E . n 
D 4 206 LEU 206 189 ?   ?   ?   E . n 
D 4 207 GLY 207 190 ?   ?   ?   E . n 
D 4 208 THR 208 191 ?   ?   ?   E . n 
D 4 209 GLN 209 192 ?   ?   ?   E . n 
D 4 210 THR 210 193 ?   ?   ?   E . n 
D 4 211 TYR 211 194 ?   ?   ?   E . n 
D 4 212 ILE 212 195 ?   ?   ?   E . n 
D 4 213 CYS 213 196 ?   ?   ?   E . n 
D 4 214 ASN 214 197 ?   ?   ?   E . n 
D 4 215 VAL 215 198 ?   ?   ?   E . n 
D 4 216 ASN 216 199 ?   ?   ?   E . n 
D 4 217 HIS 217 200 ?   ?   ?   E . n 
D 4 218 LYS 218 201 ?   ?   ?   E . n 
D 4 219 PRO 219 202 ?   ?   ?   E . n 
D 4 220 SER 220 203 ?   ?   ?   E . n 
D 4 221 ASN 221 204 ?   ?   ?   E . n 
D 4 222 THR 222 205 ?   ?   ?   E . n 
D 4 223 LYS 223 206 ?   ?   ?   E . n 
D 4 224 VAL 224 207 ?   ?   ?   E . n 
D 4 225 ASP 225 208 ?   ?   ?   E . n 
D 4 226 LYS 226 209 ?   ?   ?   E . n 
D 4 227 ARG 227 210 ?   ?   ?   E . n 
D 4 228 VAL 228 211 ?   ?   ?   E . n 
D 4 229 GLU 229 212 ?   ?   ?   E . n 
D 4 230 PRO 230 213 ?   ?   ?   E . n 
D 4 231 LYS 231 214 ?   ?   ?   E . n 
D 4 232 SER 232 215 ?   ?   ?   E . n 
E 5 1   ASP 1   0   ?   ?   ?   F . n 
E 5 2   ASP 2   1   1   ASP ASP F . n 
E 5 3   ILE 3   2   2   ILE ILE F . n 
E 5 4   GLN 4   3   3   GLN GLN F . n 
E 5 5   LEU 5   4   4   LEU LEU F . n 
E 5 6   THR 6   5   5   THR THR F . n 
E 5 7   GLN 7   6   6   GLN GLN F . n 
E 5 8   SER 8   7   7   SER SER F . n 
E 5 9   PRO 9   8   8   PRO PRO F . n 
E 5 10  SER 10  9   9   SER SER F . n 
E 5 11  PHE 11  10  10  PHE PHE F . n 
E 5 12  LEU 12  11  11  LEU LEU F . n 
E 5 13  SER 13  12  12  SER SER F . n 
E 5 14  ALA 14  13  13  ALA ALA F . n 
E 5 15  SER 15  14  14  SER SER F . n 
E 5 16  VAL 16  15  15  VAL VAL F . n 
E 5 17  GLY 17  16  16  GLY GLY F . n 
E 5 18  ASP 18  17  17  ASP ASP F . n 
E 5 19  ARG 19  18  18  ARG ARG F . n 
E 5 20  ILE 20  19  19  ILE ILE F . n 
E 5 21  THR 21  20  20  THR THR F . n 
E 5 22  ILE 22  21  21  ILE ILE F . n 
E 5 23  THR 23  22  22  THR THR F . n 
E 5 24  CYS 24  23  23  CYS CYS F . n 
E 5 25  ARG 25  24  24  ARG ARG F . n 
E 5 26  ALA 26  25  25  ALA ALA F . n 
E 5 27  SER 27  26  26  SER SER F . n 
E 5 28  GLN 28  27  27  GLN GLN F . n 
E 5 29  GLY 29  28  28  GLY GLY F . n 
E 5 30  ILE 30  29  29  ILE ILE F . n 
E 5 31  ASP 31  30  30  ASP ASP F . n 
E 5 32  GLY 32  31  31  GLY GLY F . n 
E 5 33  TYR 33  32  32  TYR TYR F . n 
E 5 34  LEU 34  33  33  LEU LEU F . n 
E 5 35  ALA 35  34  34  ALA ALA F . n 
E 5 36  TRP 36  35  35  TRP TRP F . n 
E 5 37  TYR 37  36  36  TYR TYR F . n 
E 5 38  GLN 38  37  37  GLN GLN F . n 
E 5 39  GLN 39  38  38  GLN GLN F . n 
E 5 40  ARG 40  39  39  ARG ARG F . n 
E 5 41  PRO 41  40  40  PRO PRO F . n 
E 5 42  GLY 42  41  41  GLY GLY F . n 
E 5 43  LYS 43  42  42  LYS LYS F . n 
E 5 44  ALA 44  43  43  ALA ALA F . n 
E 5 45  PRO 45  44  44  PRO PRO F . n 
E 5 46  ASN 46  45  45  ASN ASN F . n 
E 5 47  LEU 47  46  46  LEU LEU F . n 
E 5 48  LEU 48  47  47  LEU LEU F . n 
E 5 49  ILE 49  48  48  ILE ILE F . n 
E 5 50  TYR 50  49  49  TYR TYR F . n 
E 5 51  ALA 51  50  50  ALA ALA F . n 
E 5 52  ALA 52  51  51  ALA ALA F . n 
E 5 53  SER 53  52  52  SER SER F . n 
E 5 54  LEU 54  53  53  LEU LEU F . n 
E 5 55  LEU 55  54  54  LEU LEU F . n 
E 5 56  GLN 56  55  55  GLN GLN F . n 
E 5 57  SER 57  56  56  SER SER F . n 
E 5 58  GLY 58  57  57  GLY GLY F . n 
E 5 59  VAL 59  58  58  VAL VAL F . n 
E 5 60  PRO 60  59  59  PRO PRO F . n 
E 5 61  SER 61  60  60  SER SER F . n 
E 5 62  ARG 62  61  61  ARG ARG F . n 
E 5 63  PHE 63  62  62  PHE PHE F . n 
E 5 64  SER 64  63  63  SER SER F . n 
E 5 65  GLY 65  64  64  GLY GLY F . n 
E 5 66  SER 66  65  65  SER SER F . n 
E 5 67  GLY 67  66  66  GLY GLY F . n 
E 5 68  TYR 68  67  67  TYR TYR F . n 
E 5 69  GLY 69  68  68  GLY GLY F . n 
E 5 70  THR 70  69  69  THR THR F . n 
E 5 71  GLU 71  70  70  GLU GLU F . n 
E 5 72  PHE 72  71  71  PHE PHE F . n 
E 5 73  THR 73  72  72  THR THR F . n 
E 5 74  LEU 74  73  73  LEU LEU F . n 
E 5 75  THR 75  74  74  THR THR F . n 
E 5 76  ILE 76  75  75  ILE ILE F . n 
E 5 77  SER 77  76  76  SER SER F . n 
E 5 78  SER 78  77  77  SER SER F . n 
E 5 79  LEU 79  78  78  LEU LEU F . n 
E 5 80  GLN 80  79  79  GLN GLN F . n 
E 5 81  PRO 81  80  80  PRO PRO F . n 
E 5 82  GLU 82  81  81  GLU GLU F . n 
E 5 83  ASP 83  82  82  ASP ASP F . n 
E 5 84  PHE 84  83  83  PHE PHE F . n 
E 5 85  ALA 85  84  84  ALA ALA F . n 
E 5 86  THR 86  85  85  THR THR F . n 
E 5 87  TYR 87  86  86  TYR TYR F . n 
E 5 88  TYR 88  87  87  TYR TYR F . n 
E 5 89  CYS 89  88  88  CYS CYS F . n 
E 5 90  GLN 90  89  89  GLN GLN F . n 
E 5 91  HIS 91  90  90  HIS HIS F . n 
E 5 92  LEU 92  91  91  LEU LEU F . n 
E 5 93  ASP 93  92  92  ASP ASP F . n 
E 5 94  SER 94  93  93  SER SER F . n 
E 5 95  TYR 95  94  94  TYR TYR F . n 
E 5 96  PRO 96  95  95  PRO PRO F . n 
E 5 97  LEU 97  95  95  LEU LEU F A n 
E 5 98  PHE 98  96  96  PHE PHE F . n 
E 5 99  THR 99  97  97  THR THR F . n 
E 5 100 PHE 100 98  98  PHE PHE F . n 
E 5 101 GLY 101 99  99  GLY GLY F . n 
E 5 102 PRO 102 100 100 PRO PRO F . n 
E 5 103 GLY 103 101 101 GLY GLY F . n 
E 5 104 THR 104 102 102 THR THR F . n 
E 5 105 LYS 105 103 103 LYS LYS F . n 
E 5 106 VAL 106 104 104 VAL VAL F . n 
E 5 107 ASP 107 105 105 ASP ASP F . n 
E 5 108 ILE 108 106 106 ILE ILE F . n 
E 5 109 LYS 109 107 107 LYS LYS F . n 
E 5 110 ARG 110 108 108 ARG ARG F . n 
E 5 111 THR 111 109 ?   ?   ?   F . n 
E 5 112 VAL 112 110 ?   ?   ?   F . n 
E 5 113 ALA 113 111 ?   ?   ?   F . n 
E 5 114 ALA 114 112 ?   ?   ?   F . n 
E 5 115 PRO 115 113 ?   ?   ?   F . n 
E 5 116 SER 116 114 ?   ?   ?   F . n 
E 5 117 VAL 117 115 ?   ?   ?   F . n 
E 5 118 PHE 118 116 ?   ?   ?   F . n 
E 5 119 ILE 119 117 ?   ?   ?   F . n 
E 5 120 PHE 120 118 ?   ?   ?   F . n 
E 5 121 PRO 121 119 ?   ?   ?   F . n 
E 5 122 PRO 122 120 ?   ?   ?   F . n 
E 5 123 SER 123 121 ?   ?   ?   F . n 
E 5 124 ASP 124 122 ?   ?   ?   F . n 
E 5 125 GLU 125 123 ?   ?   ?   F . n 
E 5 126 GLN 126 124 ?   ?   ?   F . n 
E 5 127 LEU 127 125 ?   ?   ?   F . n 
E 5 128 LYS 128 126 ?   ?   ?   F . n 
E 5 129 SER 129 127 ?   ?   ?   F . n 
E 5 130 GLY 130 128 ?   ?   ?   F . n 
E 5 131 THR 131 129 ?   ?   ?   F . n 
E 5 132 ALA 132 130 ?   ?   ?   F . n 
E 5 133 SER 133 131 ?   ?   ?   F . n 
E 5 134 VAL 134 132 ?   ?   ?   F . n 
E 5 135 VAL 135 133 ?   ?   ?   F . n 
E 5 136 CYS 136 134 ?   ?   ?   F . n 
E 5 137 LEU 137 135 ?   ?   ?   F . n 
E 5 138 LEU 138 136 ?   ?   ?   F . n 
E 5 139 ASN 139 137 ?   ?   ?   F . n 
E 5 140 ASN 140 138 ?   ?   ?   F . n 
E 5 141 PHE 141 139 ?   ?   ?   F . n 
E 5 142 TYR 142 140 ?   ?   ?   F . n 
E 5 143 PRO 143 141 ?   ?   ?   F . n 
E 5 144 ARG 144 142 ?   ?   ?   F . n 
E 5 145 GLU 145 143 ?   ?   ?   F . n 
E 5 146 ALA 146 144 ?   ?   ?   F . n 
E 5 147 LYS 147 145 ?   ?   ?   F . n 
E 5 148 VAL 148 146 ?   ?   ?   F . n 
E 5 149 GLN 149 147 ?   ?   ?   F . n 
E 5 150 TRP 150 148 ?   ?   ?   F . n 
E 5 151 LYS 151 149 ?   ?   ?   F . n 
E 5 152 VAL 152 150 ?   ?   ?   F . n 
E 5 153 ASP 153 151 ?   ?   ?   F . n 
E 5 154 ASN 154 152 ?   ?   ?   F . n 
E 5 155 ALA 155 153 ?   ?   ?   F . n 
E 5 156 LEU 156 154 ?   ?   ?   F . n 
E 5 157 GLN 157 155 ?   ?   ?   F . n 
E 5 158 SER 158 156 ?   ?   ?   F . n 
E 5 159 GLY 159 157 ?   ?   ?   F . n 
E 5 160 ASN 160 158 ?   ?   ?   F . n 
E 5 161 SER 161 159 ?   ?   ?   F . n 
E 5 162 GLN 162 160 ?   ?   ?   F . n 
E 5 163 GLU 163 161 ?   ?   ?   F . n 
E 5 164 SER 164 162 ?   ?   ?   F . n 
E 5 165 VAL 165 163 ?   ?   ?   F . n 
E 5 166 THR 166 164 ?   ?   ?   F . n 
E 5 167 GLU 167 165 ?   ?   ?   F . n 
E 5 168 GLN 168 166 ?   ?   ?   F . n 
E 5 169 ASP 169 167 ?   ?   ?   F . n 
E 5 170 SER 170 168 ?   ?   ?   F . n 
E 5 171 LYS 171 169 ?   ?   ?   F . n 
E 5 172 ASP 172 170 ?   ?   ?   F . n 
E 5 173 SER 173 171 ?   ?   ?   F . n 
E 5 174 THR 174 172 ?   ?   ?   F . n 
E 5 175 TYR 175 173 ?   ?   ?   F . n 
E 5 176 SER 176 174 ?   ?   ?   F . n 
E 5 177 LEU 177 175 ?   ?   ?   F . n 
E 5 178 SER 178 176 ?   ?   ?   F . n 
E 5 179 SER 179 177 ?   ?   ?   F . n 
E 5 180 THR 180 178 ?   ?   ?   F . n 
E 5 181 LEU 181 179 ?   ?   ?   F . n 
E 5 182 THR 182 180 ?   ?   ?   F . n 
E 5 183 LEU 183 181 ?   ?   ?   F . n 
E 5 184 SER 184 182 ?   ?   ?   F . n 
E 5 185 LYS 185 183 ?   ?   ?   F . n 
E 5 186 ALA 186 184 ?   ?   ?   F . n 
E 5 187 ASP 187 185 ?   ?   ?   F . n 
E 5 188 TYR 188 186 ?   ?   ?   F . n 
E 5 189 GLU 189 187 ?   ?   ?   F . n 
E 5 190 LYS 190 188 ?   ?   ?   F . n 
E 5 191 HIS 191 189 ?   ?   ?   F . n 
E 5 192 LYS 192 190 ?   ?   ?   F . n 
E 5 193 VAL 193 191 ?   ?   ?   F . n 
E 5 194 TYR 194 192 ?   ?   ?   F . n 
E 5 195 ALA 195 193 ?   ?   ?   F . n 
E 5 196 CYS 196 194 ?   ?   ?   F . n 
E 5 197 GLU 197 195 ?   ?   ?   F . n 
E 5 198 VAL 198 196 ?   ?   ?   F . n 
E 5 199 THR 199 197 ?   ?   ?   F . n 
E 5 200 HIS 200 198 ?   ?   ?   F . n 
E 5 201 GLN 201 199 ?   ?   ?   F . n 
E 5 202 GLY 202 200 ?   ?   ?   F . n 
E 5 203 LEU 203 201 ?   ?   ?   F . n 
E 5 204 SER 204 202 ?   ?   ?   F . n 
E 5 205 SER 205 203 ?   ?   ?   F . n 
E 5 206 PRO 206 204 ?   ?   ?   F . n 
E 5 207 VAL 207 205 ?   ?   ?   F . n 
E 5 208 THR 208 206 ?   ?   ?   F . n 
E 5 209 LYS 209 207 ?   ?   ?   F . n 
E 5 210 SER 210 208 ?   ?   ?   F . n 
E 5 211 PHE 211 209 ?   ?   ?   F . n 
E 5 212 ASN 212 210 ?   ?   ?   F . n 
E 5 213 ARG 213 211 ?   ?   ?   F . n 
E 5 214 GLY 214 212 ?   ?   ?   F . n 
E 5 215 GLU 215 213 ?   ?   ?   F . n 
E 5 216 CYS 216 214 ?   ?   ?   F . n 
# 
loop_
_pdbx_branch_scheme.asym_id 
_pdbx_branch_scheme.entity_id 
_pdbx_branch_scheme.mon_id 
_pdbx_branch_scheme.num 
_pdbx_branch_scheme.pdb_asym_id 
_pdbx_branch_scheme.pdb_mon_id 
_pdbx_branch_scheme.pdb_seq_num 
_pdbx_branch_scheme.auth_asym_id 
_pdbx_branch_scheme.auth_mon_id 
_pdbx_branch_scheme.auth_seq_num 
_pdbx_branch_scheme.hetero 
F 6 NAG 1 D NAG 1 A NAG 601 n 
F 6 NAG 2 D NAG 2 A NAG 602 n 
# 
loop_
_pdbx_entity_instance_feature.ordinal 
_pdbx_entity_instance_feature.comp_id 
_pdbx_entity_instance_feature.asym_id 
_pdbx_entity_instance_feature.seq_num 
_pdbx_entity_instance_feature.auth_comp_id 
_pdbx_entity_instance_feature.auth_asym_id 
_pdbx_entity_instance_feature.auth_seq_num 
_pdbx_entity_instance_feature.feature_type 
_pdbx_entity_instance_feature.details 
1 CA  ? ? CA  ? ? 'SUBJECT OF INVESTIGATION' ? 
2 NAG ? ? NAG ? ? 'SUBJECT OF INVESTIGATION' ? 
# 
_pdbx_nonpoly_scheme.asym_id         G 
_pdbx_nonpoly_scheme.entity_id       7 
_pdbx_nonpoly_scheme.mon_id          CA 
_pdbx_nonpoly_scheme.ndb_seq_num     1 
_pdbx_nonpoly_scheme.pdb_seq_num     501 
_pdbx_nonpoly_scheme.auth_seq_num    580 
_pdbx_nonpoly_scheme.pdb_mon_id      CA 
_pdbx_nonpoly_scheme.auth_mon_id     CA 
_pdbx_nonpoly_scheme.pdb_strand_id   A 
_pdbx_nonpoly_scheme.pdb_ins_code    . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1 1 Y 1 B MET 49 ? CG  ? B MET 49 CG  
2 1 Y 1 B MET 49 ? SD  ? B MET 49 SD  
3 1 Y 1 B MET 49 ? CE  ? B MET 49 CE  
4 1 Y 1 B ARG 63 ? CG  ? B ARG 63 CG  
5 1 Y 1 B ARG 63 ? CD  ? B ARG 63 CD  
6 1 Y 1 B ARG 63 ? NE  ? B ARG 63 NE  
7 1 Y 1 B ARG 63 ? CZ  ? B ARG 63 CZ  
8 1 Y 1 B ARG 63 ? NH1 ? B ARG 63 NH1 
9 1 Y 1 B ARG 63 ? NH2 ? B ARG 63 NH2 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8Z4E 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_struct.entry_id                     8Z4E 
_struct.title                        
'Structure of human 18_14D scFv and 1G01 scFv in complex with influenza virus neuraminidase from A/Yunan/DQ001/2016 (H5N6)' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8Z4E 
_struct_keywords.text            'influenza virus, neuraminidase, human monoclonal antibody, immunogen, VIRAL PROTEIN' 
_struct_keywords.pdbx_keywords   'VIRAL PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
E N N 5 ? 
F N N 6 ? 
G N N 7 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP A0A0K0YAP8_9INFA A0A0K0YAP8 ? 1 
;RTFLNLTKPLCEVNSWHILSKDNAIRIGEDAHILVTREPYLSCDPQGCRMFALSQGTTLRGRHANGTIHDKSPFRALISW
EMGQAPSPYNTRVECIGWSSTSCHDGISRMSICISGPNNNASAVVWYRGRPVTEIPSWVGNILRTQESECVCHKGICPVV
MTDGPANNKAATKIIYFKEGKIQKIEELQGNAQHIEECSCYGAAGMIKCVCRDNWKGANRPIITIDPEMMTHTSKYLCSK
ILTDTSRPNDPTNGNCDEPITGGSPDPGVKGFAFLDGENSWLGRTISKDSRSGYEMLKVPNAETDTQSGPTSYQLIVNNQ
NWSGYSGAFIDYWANKECFNPCFYVELIRGRPKEIDVLWASNSMVALCGSRERLGSWSW
;
71 
2 PDB 8Z4E             8Z4E       ? 2 ? 1  
3 PDB 8Z4E             8Z4E       ? 3 ? 1  
4 PDB 8Z4E             8Z4E       ? 4 ? 1  
5 PDB 8Z4E             8Z4E       ? 5 ? 1  
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8Z4E A 1 ? 379 ? A0A0K0YAP8 71 ? 449 ? 82 460 
2 2 8Z4E B 1 ? 216 ? 8Z4E       1  ? 216 ? 1  216 
3 3 8Z4E C 1 ? 236 ? 8Z4E       1  ? 236 ? 1  236 
4 4 8Z4E E 1 ? 232 ? 8Z4E       1  ? 215 ? 1  215 
5 5 8Z4E F 1 ? 216 ? 8Z4E       0  ? 214 ? 0  214 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   pentameric 
_pdbx_struct_assembly.oligomeric_count     5 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1 AA1 PRO A 117 ? ASN A 120 ? PRO A 198 ASN A 201 5 ? 4 
HELX_P HELX_P2 AA2 ARG C 87  ? THR C 91  ? ARG C 87  THR C 91  5 ? 5 
HELX_P HELX_P3 AA3 LYS D 28  ? TYR D 32  ? LYS E 28  TYR E 32  5 ? 5 
HELX_P HELX_P4 AA4 ASP D 62  ? LYS D 65  ? ASP E 61  LYS E 64  5 ? 4 
HELX_P HELX_P5 AA5 GLN E 80  ? PHE E 84  ? GLN F 79  PHE F 83  5 ? 5 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1  disulf ?    ? A CYS 11  SG  ? ? ? 1_555 A CYS 338 SG ? ? A CYS 92  A CYS 419 1_555 ? ? ? ? ? ? ? 2.031 ? ?               
disulf2  disulf ?    ? A CYS 95  SG  ? ? ? 1_555 A CYS 113 SG ? ? A CYS 176 A CYS 194 1_555 ? ? ? ? ? ? ? 2.027 ? ?               
disulf3  disulf ?    ? A CYS 103 SG  ? ? ? 1_555 A CYS 150 SG ? ? A CYS 184 A CYS 231 1_555 ? ? ? ? ? ? ? 2.026 ? ?               
disulf4  disulf ?    ? A CYS 152 SG  ? ? ? 1_555 A CYS 157 SG ? ? A CYS 233 A CYS 238 1_555 ? ? ? ? ? ? ? 2.031 ? ?               
disulf5  disulf ?    ? A CYS 198 SG  ? ? ? 1_555 A CYS 211 SG ? ? A CYS 279 A CYS 292 1_555 ? ? ? ? ? ? ? 2.044 ? ?               
disulf6  disulf ?    ? A CYS 200 SG  ? ? ? 1_555 A CYS 209 SG ? ? A CYS 281 A CYS 290 1_555 ? ? ? ? ? ? ? 2.029 ? ?               
disulf7  disulf ?    ? A CYS 238 SG  ? ? ? 1_555 A CYS 256 SG ? ? A CYS 319 A CYS 337 1_555 ? ? ? ? ? ? ? 2.034 ? ?               
disulf8  disulf ?    ? A CYS 342 SG  ? ? ? 1_555 A CYS 368 SG ? ? A CYS 423 A CYS 449 1_555 ? ? ? ? ? ? ? 2.033 ? ?               
disulf9  disulf ?    ? B CYS 22  SG  ? ? ? 1_555 B CYS 90  SG ? ? B CYS 22  B CYS 90  1_555 ? ? ? ? ? ? ? 2.033 ? ?               
disulf10 disulf ?    ? C CYS 22  SG  ? ? ? 1_555 C CYS 96  SG ? ? C CYS 22  C CYS 96  1_555 ? ? ? ? ? ? ? 2.032 ? ?               
disulf11 disulf ?    ? D CYS 22  SG  ? ? ? 1_555 D CYS 96  SG ? ? E CYS 22  E CYS 92  1_555 ? ? ? ? ? ? ? 2.029 ? ?               
disulf12 disulf ?    ? E CYS 24  SG  ? ? ? 1_555 E CYS 89  SG ? ? F CYS 23  F CYS 88  1_555 ? ? ? ? ? ? ? 2.034 ? ?               
covale1  covale one  ? A ASN 120 ND2 ? ? ? 1_555 F NAG .   C1 ? ? A ASN 201 D NAG 1   1_555 ? ? ? ? ? ? ? 1.441 ? N-Glycosylation 
covale2  covale both ? F NAG .   O4  ? ? ? 1_555 F NAG .   C1 ? ? D NAG 1   D NAG 2   1_555 ? ? ? ? ? ? ? 1.441 ? ?               
metalc1  metalc ?    ? A ASP 213 O   ? ? ? 1_555 G CA  .   CA ? ? A ASP 294 A CA  501 1_555 ? ? ? ? ? ? ? 2.545 ? ?               
metalc2  metalc ?    ? A GLY 217 O   ? ? ? 1_555 G CA  .   CA ? ? A GLY 298 A CA  501 1_555 ? ? ? ? ? ? ? 2.407 ? ?               
metalc3  metalc ?    ? A PRO 267 O   ? ? ? 1_555 G CA  .   CA ? ? A PRO 348 A CA  501 1_555 ? ? ? ? ? ? ? 2.394 ? ?               
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
disulf ? ? 
covale ? ? 
metalc ? ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1 O ? A ASP 213 ? A ASP 294 ? 1_555 CA ? G CA . ? A CA 501 ? 1_555 O ? A GLY 217 ? A GLY 298 ? 1_555 74.8  ? 
2 O ? A ASP 213 ? A ASP 294 ? 1_555 CA ? G CA . ? A CA 501 ? 1_555 O ? A PRO 267 ? A PRO 348 ? 1_555 109.2 ? 
3 O ? A GLY 217 ? A GLY 298 ? 1_555 CA ? G CA . ? A CA 501 ? 1_555 O ? A PRO 267 ? A PRO 348 ? 1_555 164.3 ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1  NAG F .   ? ASN A 120 ? NAG D 1   ? 1_555 ASN A 201 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
2  CYS A 11  ? CYS A 338 ? CYS A 92  ? 1_555 CYS A 419 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
3  CYS A 95  ? CYS A 113 ? CYS A 176 ? 1_555 CYS A 194 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
4  CYS A 103 ? CYS A 150 ? CYS A 184 ? 1_555 CYS A 231 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
5  CYS A 152 ? CYS A 157 ? CYS A 233 ? 1_555 CYS A 238 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
6  CYS A 198 ? CYS A 211 ? CYS A 279 ? 1_555 CYS A 292 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
7  CYS A 200 ? CYS A 209 ? CYS A 281 ? 1_555 CYS A 290 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
8  CYS A 238 ? CYS A 256 ? CYS A 319 ? 1_555 CYS A 337 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
9  CYS A 342 ? CYS A 368 ? CYS A 423 ? 1_555 CYS A 449 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
10 CYS B 22  ? CYS B 90  ? CYS B 22  ? 1_555 CYS B 90  ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
11 CYS C 22  ? CYS C 96  ? CYS C 22  ? 1_555 CYS C 96  ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
12 CYS D 22  ? CYS D 96  ? CYS E 22  ? 1_555 CYS E 92  ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
13 CYS E 24  ? CYS E 89  ? CYS F 23  ? 1_555 CYS F 88  ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 THR 245 A . ? THR 326 A SER 246 A ? SER 327 A 1 5.07  
2 SER 264 A . ? SER 345 A PRO 265 A ? PRO 346 A 1 -2.30 
3 SER 8   E . ? SER 7   F PRO 9   E ? PRO 8   F 1 -4.95 
4 TYR 95  E . ? TYR 94  F PRO 96  E ? PRO 95  F 1 -4.62 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 4 ? 
AA2 ? 4 ? 
AA3 ? 3 ? 
AA4 ? 4 ? 
AA5 ? 5 ? 
AA6 ? 3 ? 
AA7 ? 3 ? 
AA8 ? 4 ? 
AA9 ? 4 ? 
AB1 ? 6 ? 
AB2 ? 3 ? 
AB3 ? 4 ? 
AB4 ? 5 ? 
AB5 ? 5 ? 
AB6 ? 4 ? 
AB7 ? 6 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA5 4 5 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AB1 1 2 ? parallel      
AB1 2 3 ? anti-parallel 
AB1 3 4 ? anti-parallel 
AB1 4 5 ? anti-parallel 
AB1 5 6 ? anti-parallel 
AB2 1 2 ? anti-parallel 
AB2 2 3 ? anti-parallel 
AB3 1 2 ? anti-parallel 
AB3 2 3 ? anti-parallel 
AB3 3 4 ? anti-parallel 
AB4 1 2 ? anti-parallel 
AB4 2 3 ? anti-parallel 
AB4 3 4 ? anti-parallel 
AB4 4 5 ? anti-parallel 
AB5 1 2 ? anti-parallel 
AB5 2 3 ? anti-parallel 
AB5 3 4 ? anti-parallel 
AB5 4 5 ? anti-parallel 
AB6 1 2 ? anti-parallel 
AB6 2 3 ? anti-parallel 
AB6 3 4 ? anti-parallel 
AB7 1 2 ? parallel      
AB7 2 3 ? anti-parallel 
AB7 3 4 ? anti-parallel 
AB7 4 5 ? anti-parallel 
AB7 5 6 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 THR A 36  ? ASP A 44  ? THR A 117 ASP A 125 
AA1 2 GLY A 47  ? SER A 54  ? GLY A 128 SER A 135 
AA1 3 ALA A 76  ? GLU A 81  ? ALA A 157 GLU A 162 
AA1 4 ARG A 92  ? ILE A 96  ? ARG A 173 ILE A 177 
AA2 1 SER A 99  ? HIS A 104 ? SER A 180 HIS A 185 
AA2 2 ARG A 109 ? SER A 115 ? ARG A 190 SER A 196 
AA2 3 SER A 122 ? TYR A 127 ? SER A 203 TYR A 208 
AA2 4 ARG A 130 ? PRO A 136 ? ARG A 211 PRO A 217 
AA3 1 CYS A 157 ? ASP A 163 ? CYS A 238 ASP A 244 
AA3 2 ALA A 171 ? LYS A 178 ? ALA A 252 LYS A 259 
AA3 3 LYS A 181 ? GLU A 187 ? LYS A 262 GLU A 268 
AA4 1 GLU A 196 ? ALA A 203 ? GLU A 277 ALA A 284 
AA4 2 MET A 206 ? ARG A 212 ? MET A 287 ARG A 293 
AA4 3 PRO A 221 ? ASP A 226 ? PRO A 302 ASP A 307 
AA4 4 THR A 231 ? TYR A 236 ? THR A 312 TYR A 317 
AA5 1 ALA A 273 ? ASP A 276 ? ALA A 354 ASP A 357 
AA5 2 ASN A 279 ? ARG A 284 ? ASN A 360 ARG A 365 
AA5 3 SER A 292 ? LEU A 297 ? SER A 373 LEU A 378 
AA5 4 TYR A 313 ? TRP A 322 ? TYR A 394 TRP A 403 
AA5 5 TYR C 103 ? PHE C 104 ? TYR C 103 PHE C 104 
AA6 1 SER A 326 ? ILE A 330 ? SER A 407 ILE A 411 
AA6 2 PRO A 341 ? GLU A 346 ? PRO A 422 GLU A 427 
AA6 3 MET A 364 ? LEU A 367 ? MET A 445 LEU A 448 
AA7 1 ILE B 18  ? THR B 23  ? ILE B 18  THR B 23  
AA7 2 THR B 72  ? ILE B 77  ? THR B 72  ILE B 77  
AA7 3 PHE B 64  ? SER B 69  ? PHE B 64  SER B 69  
AA8 1 LYS B 47  ? ILE B 50  ? LYS B 47  ILE B 50  
AA8 2 VAL B 35  ? GLN B 40  ? VAL B 35  GLN B 40  
AA8 3 ALA B 86  ? TYR B 93  ? ALA B 86  TYR B 93  
AA8 4 TRP B 99  ? PHE B 101 ? TRP B 99  PHE B 101 
AA9 1 LYS B 47  ? ILE B 50  ? LYS B 47  ILE B 50  
AA9 2 VAL B 35  ? GLN B 40  ? VAL B 35  GLN B 40  
AA9 3 ALA B 86  ? TYR B 93  ? ALA B 86  TYR B 93  
AA9 4 THR B 105 ? LEU B 107 ? THR B 105 LEU B 107 
AB1 1 GLU C 10  ? LYS C 12  ? GLU C 10  LYS C 12  
AB1 2 THR C 123 ? VAL C 127 ? THR C 123 VAL C 127 
AB1 3 ALA C 92  ? GLN C 100 ? ALA C 92  GLN C 100 
AB1 4 TYR C 32  ? GLN C 39  ? TYR C 32  GLN C 39  
AB1 5 LEU C 45  ? ILE C 52  ? LEU C 45  ILE C 52  
AB1 6 THR C 57  ? TYR C 60  ? THR C 57  TYR C 60  
AB2 1 VAL C 18  ? LYS C 23  ? VAL C 18  LYS C 23  
AB2 2 THR C 78  ? LEU C 83  ? THR C 78  LEU C 83  
AB2 3 VAL C 68  ? ASP C 73  ? VAL C 68  ASP C 73  
AB3 1 GLN D 3   ? SER D 7   ? GLN E 3   SER E 7   
AB3 2 SER D 17  ? SER D 25  ? SER E 17  SER E 25  
AB3 3 SER D 78  ? ASN D 84  A SER E 77  ASN E 82  
AB3 4 PHE D 68  ? ASP D 73  ? PHE E 67  ASP E 72  
AB4 1 THR D 58  ? TYR D 60  ? THR E 57  TYR E 59  
AB4 2 LEU D 45  ? LEU D 51  ? LEU E 45  LEU E 51  
AB4 3 ALA D 33  ? GLN D 39  ? ALA E 33  GLN E 39  
AB4 4 ALA D 92  ? SER D 101 ? ALA E 88  SER E 97  
AB4 5 TRP D 115 K LEU D 119 ? TRP E 100 LEU E 102 
AB5 1 THR D 58  ? TYR D 60  ? THR E 57  TYR E 59  
AB5 2 LEU D 45  ? LEU D 51  ? LEU E 45  LEU E 51  
AB5 3 ALA D 33  ? GLN D 39  ? ALA E 33  GLN E 39  
AB5 4 ALA D 92  ? SER D 101 ? ALA E 88  SER E 97  
AB5 5 THR D 124 ? VAL D 126 ? THR E 107 VAL E 109 
AB6 1 LEU E 5   ? SER E 8   ? LEU F 4   SER F 7   
AB6 2 ILE E 20  ? ALA E 26  ? ILE F 19  ALA F 25  
AB6 3 GLU E 71  ? ILE E 76  ? GLU F 70  ILE F 75  
AB6 4 PHE E 63  ? SER E 66  ? PHE F 62  SER F 65  
AB7 1 PHE E 11  ? SER E 13  ? PHE F 10  SER F 12  
AB7 2 THR E 104 ? ASP E 107 ? THR F 102 ASP F 105 
AB7 3 THR E 86  ? HIS E 91  ? THR F 85  HIS F 90  
AB7 4 LEU E 34  ? GLN E 39  ? LEU F 33  GLN F 38  
AB7 5 ASN E 46  ? TYR E 50  ? ASN F 45  TYR F 49  
AB7 6 LEU E 54  ? LEU E 55  ? LEU F 53  LEU F 54  
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N SER A 42  ? N SER A 123 O ARG A 49  ? O ARG A 130 
AA1 2 3 N MET A 50  ? N MET A 131 O TRP A 80  ? O TRP A 161 
AA1 3 4 N LEU A 77  ? N LEU A 158 O CYS A 95  ? O CYS A 176 
AA2 1 2 N THR A 101 ? N THR A 182 O ILE A 112 ? O ILE A 193 
AA2 2 3 N SER A 115 ? N SER A 196 O SER A 122 ? O SER A 203 
AA2 3 4 N VAL A 125 ? N VAL A 206 O VAL A 132 ? O VAL A 213 
AA3 1 2 N VAL A 159 ? N VAL A 240 O ILE A 175 ? O ILE A 256 
AA3 2 3 N TYR A 176 ? N TYR A 257 O LYS A 184 ? O LYS A 265 
AA4 1 2 N TYR A 201 ? N TYR A 282 O LYS A 208 ? O LYS A 289 
AA4 2 3 N ILE A 207 ? N ILE A 288 O ILE A 225 ? O ILE A 306 
AA4 3 4 N ASP A 226 ? N ASP A 307 O THR A 231 ? O THR A 312 
AA5 1 2 N PHE A 274 ? N PHE A 355 O TRP A 281 ? O TRP A 362 
AA5 2 3 N ARG A 284 ? N ARG A 365 O GLU A 295 ? O GLU A 376 
AA5 3 4 N TYR A 294 ? N TYR A 375 O VAL A 317 ? O VAL A 398 
AA5 4 5 N TYR A 313 ? N TYR A 394 O PHE C 104 ? O PHE C 104 
AA6 1 2 N PHE A 329 ? N PHE A 410 O CYS A 342 ? O CYS A 423 
AA6 2 3 N PHE A 343 ? N PHE A 424 O LEU A 367 ? O LEU A 448 
AA7 1 2 N CYS B 22  ? N CYS B 22  O ALA B 73  ? O ALA B 73  
AA7 2 3 O SER B 74  ? O SER B 74  N SER B 67  ? N SER B 67  
AA8 1 2 O ILE B 50  ? O ILE B 50  N TRP B 37  ? N TRP B 37  
AA8 2 3 N GLN B 40  ? N GLN B 40  O ASP B 87  ? O ASP B 87  
AA8 3 4 N SER B 92  ? N SER B 92  O VAL B 100 ? O VAL B 100 
AA9 1 2 O ILE B 50  ? O ILE B 50  N TRP B 37  ? N TRP B 37  
AA9 2 3 N GLN B 40  ? N GLN B 40  O ASP B 87  ? O ASP B 87  
AA9 3 4 N ALA B 86  ? N ALA B 86  O LEU B 107 ? O LEU B 107 
AB1 1 2 N LYS C 12  ? N LYS C 12  O THR C 126 ? O THR C 126 
AB1 2 3 O THR C 123 ? O THR C 123 N TYR C 94  ? N TYR C 94  
AB1 3 4 O ALA C 97  ? O ALA C 97  N SER C 35  ? N SER C 35  
AB1 4 5 N ARG C 38  ? N ARG C 38  O GLU C 46  ? O GLU C 46  
AB1 5 6 N GLY C 50  ? N GLY C 50  O ASN C 59  ? O ASN C 59  
AB2 1 2 N CYS C 22  ? N CYS C 22  O ALA C 79  ? O ALA C 79  
AB2 2 3 O GLU C 82  ? O GLU C 82  N THR C 69  ? N THR C 69  
AB3 1 2 N SER D 7   ? N SER E 7   O SER D 21  ? O SER E 21  
AB3 2 3 N LEU D 20  ? N LEU E 20  O LEU D 81  ? O LEU E 80  
AB3 3 4 O TYR D 80  ? O TYR E 79  N SER D 71  ? N SER E 70  
AB4 1 2 O ALA D 59  ? O ALA E 58  N GLY D 50  ? N GLY E 50  
AB4 2 3 O GLU D 46  ? O GLU E 46  N ARG D 38  ? N ARG E 38  
AB4 3 4 N GLN D 39  ? N GLN E 39  O LEU D 93  ? O LEU E 89  
AB4 4 5 N SER D 100 ? N SER E 96  O TYR D 116 L O TYR E 100 
AB5 1 2 O ALA D 59  ? O ALA E 58  N GLY D 50  ? N GLY E 50  
AB5 2 3 O GLU D 46  ? O GLU E 46  N ARG D 38  ? N ARG E 38  
AB5 3 4 N GLN D 39  ? N GLN E 39  O LEU D 93  ? O LEU E 89  
AB5 4 5 N TYR D 94  ? N TYR E 90  O THR D 124 ? O THR E 107 
AB6 1 2 N THR E 6   ? N THR F 5   O ARG E 25  ? O ARG F 24  
AB6 2 3 N CYS E 24  ? N CYS F 23  O PHE E 72  ? O PHE F 71  
AB6 3 4 O THR E 75  ? O THR F 74  N SER E 64  ? N SER F 63  
AB7 1 2 N LEU E 12  ? N LEU F 11  O LYS E 105 ? O LYS F 103 
AB7 2 3 O THR E 104 ? O THR F 102 N TYR E 87  ? N TYR F 86  
AB7 3 4 O THR E 86  ? O THR F 85  N GLN E 39  ? N GLN F 38  
AB7 4 5 N GLN E 38  ? N GLN F 37  O ASN E 46  ? O ASN F 45  
AB7 5 6 N TYR E 50  ? N TYR F 49  O LEU E 54  ? O LEU F 53  
# 
_pdbx_entry_details.entry_id                   8Z4E 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 PRO A 169 ? ? -73.21  49.57   
2  1 CYS A 184 ? ? -161.91 -168.01 
3  1 ILE A 223 ? ? 52.83   90.91   
4  1 ASN A 249 ? ? -161.66 -168.81 
5  1 CYS A 292 ? ? -165.55 -164.86 
6  1 TRP A 296 ? ? -97.57  -62.02  
7  1 THR A 392 ? ? -118.90 -121.95 
8  1 SER A 393 ? ? -32.23  112.05  
9  1 ASN A 421 ? ? 53.95   75.45   
10 1 CYS A 449 ? ? -172.88 146.59  
11 1 SER A 451 ? ? -126.03 -166.86 
12 1 ALA B 8   ? ? 169.35  -72.60  
13 1 ASN B 33  ? ? -91.06  57.62   
14 1 VAL B 53  ? ? 62.41   -66.14  
15 1 VAL B 60  ? ? 67.13   120.92  
16 1 LEU B 80  ? ? -58.67  109.28  
17 1 GLN B 81  ? ? -85.10  -70.82  
18 1 ALA B 82  ? ? -125.13 -57.03  
19 1 ASP B 84  ? ? -69.58  4.83    
20 1 ALA B 86  ? ? -170.98 -175.31 
21 1 GLN C 3   ? ? 63.41   -70.99  
22 1 GLN C 6   ? ? -93.14  -64.79  
23 1 SER C 7   ? ? 176.85  -89.84  
24 1 ALA C 92  ? ? -167.83 -168.95 
25 1 SER C 112 ? ? -58.62  170.12  
26 1 PRO E 41  ? ? -64.70  1.80    
27 1 VAL E 48  ? ? -125.29 -52.24  
28 1 ASP F 30  ? ? 58.79   -138.22 
29 1 LEU F 47  ? ? -94.75  -61.39  
30 1 ALA F 50  ? ? 59.89   17.83   
31 1 ALA F 51  ? ? 71.52   -7.03   
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8Z4E 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    8Z4E 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.0 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               116206 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.5 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 
'Structure of human 18_14D C and 1G01 scFv in complex with influenza virus neuraminidase from A/Yunan/DQ001/2016 (H5N6)' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       '1, 2, 3, 4, 5' 
# 
_em_imaging.entry_id                        8Z4E 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             1000 
_em_imaging.nominal_defocus_max             2000 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              8Z4E 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                8Z4E 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A LYS 102 ? A LYS 21  
2   1 Y 1 A ASP 103 ? A ASP 22  
3   1 Y 1 A ASN 104 ? A ASN 23  
4   1 Y 1 A ALA 105 ? A ALA 24  
5   1 Y 1 A ILE 106 ? A ILE 25  
6   1 Y 1 A ARG 107 ? A ARG 26  
7   1 Y 1 A ILE 108 ? A ILE 27  
8   1 Y 1 A GLY 109 ? A GLY 28  
9   1 Y 1 A GLU 110 ? A GLU 29  
10  1 Y 1 A ASP 111 ? A ASP 30  
11  1 Y 1 A THR 138 ? A THR 57  
12  1 Y 1 A THR 139 ? A THR 58  
13  1 Y 1 A LEU 140 ? A LEU 59  
14  1 Y 1 A ARG 141 ? A ARG 60  
15  1 Y 1 A GLY 142 ? A GLY 61  
16  1 Y 1 A ARG 143 ? A ARG 62  
17  1 Y 1 A HIS 144 ? A HIS 63  
18  1 Y 1 A ALA 145 ? A ALA 64  
19  1 Y 1 A ASN 146 ? A ASN 65  
20  1 Y 1 A GLY 147 ? A GLY 66  
21  1 Y 1 A THR 148 ? A THR 67  
22  1 Y 1 A ILE 149 ? A ILE 68  
23  1 Y 1 A HIS 150 ? A HIS 69  
24  1 Y 1 A ASP 151 ? A ASP 70  
25  1 Y 1 A LYS 152 ? A LYS 71  
26  1 Y 1 A SER 153 ? A SER 72  
27  1 Y 1 A ILE 429 ? A ILE 348 
28  1 Y 1 A ARG 430 ? A ARG 349 
29  1 Y 1 A GLY 431 ? A GLY 350 
30  1 Y 1 A ARG 432 ? A ARG 351 
31  1 Y 1 A PRO 433 ? A PRO 352 
32  1 Y 1 A LYS 434 ? A LYS 353 
33  1 Y 1 A GLU 435 ? A GLU 354 
34  1 Y 1 A ILE 436 ? A ILE 355 
35  1 Y 1 A ASP 437 ? A ASP 356 
36  1 Y 1 A VAL 438 ? A VAL 357 
37  1 Y 1 A LEU 439 ? A LEU 358 
38  1 Y 1 A TRP 440 ? A TRP 359 
39  1 Y 1 A ALA 441 ? A ALA 360 
40  1 Y 1 A SER 442 ? A SER 361 
41  1 Y 1 B GLN 1   ? B GLN 1   
42  1 Y 1 B LYS 114 ? B LYS 114 
43  1 Y 1 B ALA 115 ? B ALA 115 
44  1 Y 1 B ALA 116 ? B ALA 116 
45  1 Y 1 B PRO 117 ? B PRO 117 
46  1 Y 1 B SER 118 ? B SER 118 
47  1 Y 1 B VAL 119 ? B VAL 119 
48  1 Y 1 B THR 120 ? B THR 120 
49  1 Y 1 B LEU 121 ? B LEU 121 
50  1 Y 1 B PHE 122 ? B PHE 122 
51  1 Y 1 B PRO 123 ? B PRO 123 
52  1 Y 1 B PRO 124 ? B PRO 124 
53  1 Y 1 B SER 125 ? B SER 125 
54  1 Y 1 B SER 126 ? B SER 126 
55  1 Y 1 B GLU 127 ? B GLU 127 
56  1 Y 1 B GLU 128 ? B GLU 128 
57  1 Y 1 B LEU 129 ? B LEU 129 
58  1 Y 1 B GLN 130 ? B GLN 130 
59  1 Y 1 B ALA 131 ? B ALA 131 
60  1 Y 1 B ASN 132 ? B ASN 132 
61  1 Y 1 B LYS 133 ? B LYS 133 
62  1 Y 1 B ALA 134 ? B ALA 134 
63  1 Y 1 B THR 135 ? B THR 135 
64  1 Y 1 B LEU 136 ? B LEU 136 
65  1 Y 1 B VAL 137 ? B VAL 137 
66  1 Y 1 B CYS 138 ? B CYS 138 
67  1 Y 1 B LEU 139 ? B LEU 139 
68  1 Y 1 B ILE 140 ? B ILE 140 
69  1 Y 1 B SER 141 ? B SER 141 
70  1 Y 1 B ASP 142 ? B ASP 142 
71  1 Y 1 B PHE 143 ? B PHE 143 
72  1 Y 1 B TYR 144 ? B TYR 144 
73  1 Y 1 B PRO 145 ? B PRO 145 
74  1 Y 1 B GLY 146 ? B GLY 146 
75  1 Y 1 B ALA 147 ? B ALA 147 
76  1 Y 1 B VAL 148 ? B VAL 148 
77  1 Y 1 B THR 149 ? B THR 149 
78  1 Y 1 B VAL 150 ? B VAL 150 
79  1 Y 1 B ALA 151 ? B ALA 151 
80  1 Y 1 B TRP 152 ? B TRP 152 
81  1 Y 1 B LYS 153 ? B LYS 153 
82  1 Y 1 B ALA 154 ? B ALA 154 
83  1 Y 1 B ASP 155 ? B ASP 155 
84  1 Y 1 B SER 156 ? B SER 156 
85  1 Y 1 B SER 157 ? B SER 157 
86  1 Y 1 B PRO 158 ? B PRO 158 
87  1 Y 1 B VAL 159 ? B VAL 159 
88  1 Y 1 B LYS 160 ? B LYS 160 
89  1 Y 1 B ALA 161 ? B ALA 161 
90  1 Y 1 B GLY 162 ? B GLY 162 
91  1 Y 1 B VAL 163 ? B VAL 163 
92  1 Y 1 B GLU 164 ? B GLU 164 
93  1 Y 1 B THR 165 ? B THR 165 
94  1 Y 1 B THR 166 ? B THR 166 
95  1 Y 1 B THR 167 ? B THR 167 
96  1 Y 1 B PRO 168 ? B PRO 168 
97  1 Y 1 B SER 169 ? B SER 169 
98  1 Y 1 B LYS 170 ? B LYS 170 
99  1 Y 1 B GLN 171 ? B GLN 171 
100 1 Y 1 B SER 172 ? B SER 172 
101 1 Y 1 B ASN 173 ? B ASN 173 
102 1 Y 1 B ASN 174 ? B ASN 174 
103 1 Y 1 B LYS 175 ? B LYS 175 
104 1 Y 1 B TYR 176 ? B TYR 176 
105 1 Y 1 B ALA 177 ? B ALA 177 
106 1 Y 1 B ALA 178 ? B ALA 178 
107 1 Y 1 B SER 179 ? B SER 179 
108 1 Y 1 B SER 180 ? B SER 180 
109 1 Y 1 B TYR 181 ? B TYR 181 
110 1 Y 1 B LEU 182 ? B LEU 182 
111 1 Y 1 B SER 183 ? B SER 183 
112 1 Y 1 B LEU 184 ? B LEU 184 
113 1 Y 1 B THR 185 ? B THR 185 
114 1 Y 1 B PRO 186 ? B PRO 186 
115 1 Y 1 B GLU 187 ? B GLU 187 
116 1 Y 1 B GLN 188 ? B GLN 188 
117 1 Y 1 B TRP 189 ? B TRP 189 
118 1 Y 1 B LYS 190 ? B LYS 190 
119 1 Y 1 B SER 191 ? B SER 191 
120 1 Y 1 B HIS 192 ? B HIS 192 
121 1 Y 1 B ARG 193 ? B ARG 193 
122 1 Y 1 B SER 194 ? B SER 194 
123 1 Y 1 B TYR 195 ? B TYR 195 
124 1 Y 1 B SER 196 ? B SER 196 
125 1 Y 1 B CYS 197 ? B CYS 197 
126 1 Y 1 B GLN 198 ? B GLN 198 
127 1 Y 1 B VAL 199 ? B VAL 199 
128 1 Y 1 B THR 200 ? B THR 200 
129 1 Y 1 B HIS 201 ? B HIS 201 
130 1 Y 1 B GLU 202 ? B GLU 202 
131 1 Y 1 B GLY 203 ? B GLY 203 
132 1 Y 1 B SER 204 ? B SER 204 
133 1 Y 1 B THR 205 ? B THR 205 
134 1 Y 1 B VAL 206 ? B VAL 206 
135 1 Y 1 B GLU 207 ? B GLU 207 
136 1 Y 1 B LYS 208 ? B LYS 208 
137 1 Y 1 B THR 209 ? B THR 209 
138 1 Y 1 B VAL 210 ? B VAL 210 
139 1 Y 1 B ALA 211 ? B ALA 211 
140 1 Y 1 B PRO 212 ? B PRO 212 
141 1 Y 1 B THR 213 ? B THR 213 
142 1 Y 1 B GLU 214 ? B GLU 214 
143 1 Y 1 B CYS 215 ? B CYS 215 
144 1 Y 1 B SER 216 ? B SER 216 
145 1 Y 1 C SER 131 ? C SER 131 
146 1 Y 1 C THR 132 ? C THR 132 
147 1 Y 1 C LYS 133 ? C LYS 133 
148 1 Y 1 C GLY 134 ? C GLY 134 
149 1 Y 1 C PRO 135 ? C PRO 135 
150 1 Y 1 C SER 136 ? C SER 136 
151 1 Y 1 C VAL 137 ? C VAL 137 
152 1 Y 1 C PHE 138 ? C PHE 138 
153 1 Y 1 C PRO 139 ? C PRO 139 
154 1 Y 1 C LEU 140 ? C LEU 140 
155 1 Y 1 C ALA 141 ? C ALA 141 
156 1 Y 1 C PRO 142 ? C PRO 142 
157 1 Y 1 C SER 143 ? C SER 143 
158 1 Y 1 C SER 144 ? C SER 144 
159 1 Y 1 C LYS 145 ? C LYS 145 
160 1 Y 1 C SER 146 ? C SER 146 
161 1 Y 1 C THR 147 ? C THR 147 
162 1 Y 1 C SER 148 ? C SER 148 
163 1 Y 1 C GLY 149 ? C GLY 149 
164 1 Y 1 C GLY 150 ? C GLY 150 
165 1 Y 1 C THR 151 ? C THR 151 
166 1 Y 1 C ALA 152 ? C ALA 152 
167 1 Y 1 C ALA 153 ? C ALA 153 
168 1 Y 1 C LEU 154 ? C LEU 154 
169 1 Y 1 C GLY 155 ? C GLY 155 
170 1 Y 1 C CYS 156 ? C CYS 156 
171 1 Y 1 C LEU 157 ? C LEU 157 
172 1 Y 1 C VAL 158 ? C VAL 158 
173 1 Y 1 C LYS 159 ? C LYS 159 
174 1 Y 1 C ASP 160 ? C ASP 160 
175 1 Y 1 C TYR 161 ? C TYR 161 
176 1 Y 1 C PHE 162 ? C PHE 162 
177 1 Y 1 C PRO 163 ? C PRO 163 
178 1 Y 1 C GLU 164 ? C GLU 164 
179 1 Y 1 C PRO 165 ? C PRO 165 
180 1 Y 1 C VAL 166 ? C VAL 166 
181 1 Y 1 C THR 167 ? C THR 167 
182 1 Y 1 C VAL 168 ? C VAL 168 
183 1 Y 1 C SER 169 ? C SER 169 
184 1 Y 1 C TRP 170 ? C TRP 170 
185 1 Y 1 C ASN 171 ? C ASN 171 
186 1 Y 1 C SER 172 ? C SER 172 
187 1 Y 1 C GLY 173 ? C GLY 173 
188 1 Y 1 C ALA 174 ? C ALA 174 
189 1 Y 1 C LEU 175 ? C LEU 175 
190 1 Y 1 C THR 176 ? C THR 176 
191 1 Y 1 C SER 177 ? C SER 177 
192 1 Y 1 C GLY 178 ? C GLY 178 
193 1 Y 1 C VAL 179 ? C VAL 179 
194 1 Y 1 C HIS 180 ? C HIS 180 
195 1 Y 1 C THR 181 ? C THR 181 
196 1 Y 1 C PHE 182 ? C PHE 182 
197 1 Y 1 C PRO 183 ? C PRO 183 
198 1 Y 1 C ALA 184 ? C ALA 184 
199 1 Y 1 C VAL 185 ? C VAL 185 
200 1 Y 1 C LEU 186 ? C LEU 186 
201 1 Y 1 C GLN 187 ? C GLN 187 
202 1 Y 1 C SER 188 ? C SER 188 
203 1 Y 1 C SER 189 ? C SER 189 
204 1 Y 1 C GLY 190 ? C GLY 190 
205 1 Y 1 C LEU 191 ? C LEU 191 
206 1 Y 1 C TYR 192 ? C TYR 192 
207 1 Y 1 C SER 193 ? C SER 193 
208 1 Y 1 C LEU 194 ? C LEU 194 
209 1 Y 1 C SER 195 ? C SER 195 
210 1 Y 1 C SER 196 ? C SER 196 
211 1 Y 1 C VAL 197 ? C VAL 197 
212 1 Y 1 C VAL 198 ? C VAL 198 
213 1 Y 1 C THR 199 ? C THR 199 
214 1 Y 1 C VAL 200 ? C VAL 200 
215 1 Y 1 C PRO 201 ? C PRO 201 
216 1 Y 1 C SER 202 ? C SER 202 
217 1 Y 1 C SER 203 ? C SER 203 
218 1 Y 1 C SER 204 ? C SER 204 
219 1 Y 1 C LEU 205 ? C LEU 205 
220 1 Y 1 C GLY 206 ? C GLY 206 
221 1 Y 1 C THR 207 ? C THR 207 
222 1 Y 1 C GLN 208 ? C GLN 208 
223 1 Y 1 C THR 209 ? C THR 209 
224 1 Y 1 C TYR 210 ? C TYR 210 
225 1 Y 1 C ILE 211 ? C ILE 211 
226 1 Y 1 C CYS 212 ? C CYS 212 
227 1 Y 1 C ASN 213 ? C ASN 213 
228 1 Y 1 C VAL 214 ? C VAL 214 
229 1 Y 1 C ASN 215 ? C ASN 215 
230 1 Y 1 C HIS 216 ? C HIS 216 
231 1 Y 1 C LYS 217 ? C LYS 217 
232 1 Y 1 C PRO 218 ? C PRO 218 
233 1 Y 1 C SER 219 ? C SER 219 
234 1 Y 1 C ASN 220 ? C ASN 220 
235 1 Y 1 C THR 221 ? C THR 221 
236 1 Y 1 C LYS 222 ? C LYS 222 
237 1 Y 1 C VAL 223 ? C VAL 223 
238 1 Y 1 C ASP 224 ? C ASP 224 
239 1 Y 1 C LYS 225 ? C LYS 225 
240 1 Y 1 C ARG 226 ? C ARG 226 
241 1 Y 1 C VAL 227 ? C VAL 227 
242 1 Y 1 C GLU 228 ? C GLU 228 
243 1 Y 1 C PRO 229 ? C PRO 229 
244 1 Y 1 C LYS 230 ? C LYS 230 
245 1 Y 1 C SER 231 ? C SER 231 
246 1 Y 1 C CYS 232 ? C CYS 232 
247 1 Y 1 C ASP 233 ? C ASP 233 
248 1 Y 1 C LYS 234 ? C LYS 234 
249 1 Y 1 C THR 235 ? C THR 235 
250 1 Y 1 C HIS 236 ? C HIS 236 
251 1 Y 1 E SER 115 ? D SER 132 
252 1 Y 1 E THR 116 ? D THR 133 
253 1 Y 1 E LYS 117 ? D LYS 134 
254 1 Y 1 E GLY 118 ? D GLY 135 
255 1 Y 1 E PRO 119 ? D PRO 136 
256 1 Y 1 E SER 120 ? D SER 137 
257 1 Y 1 E VAL 121 ? D VAL 138 
258 1 Y 1 E PHE 122 ? D PHE 139 
259 1 Y 1 E PRO 123 ? D PRO 140 
260 1 Y 1 E LEU 124 ? D LEU 141 
261 1 Y 1 E ALA 125 ? D ALA 142 
262 1 Y 1 E PRO 126 ? D PRO 143 
263 1 Y 1 E SER 127 ? D SER 144 
264 1 Y 1 E SER 128 ? D SER 145 
265 1 Y 1 E LYS 129 ? D LYS 146 
266 1 Y 1 E SER 130 ? D SER 147 
267 1 Y 1 E THR 131 ? D THR 148 
268 1 Y 1 E SER 132 ? D SER 149 
269 1 Y 1 E GLY 133 ? D GLY 150 
270 1 Y 1 E GLY 134 ? D GLY 151 
271 1 Y 1 E THR 135 ? D THR 152 
272 1 Y 1 E ALA 136 ? D ALA 153 
273 1 Y 1 E ALA 137 ? D ALA 154 
274 1 Y 1 E LEU 138 ? D LEU 155 
275 1 Y 1 E GLY 139 ? D GLY 156 
276 1 Y 1 E CYS 140 ? D CYS 157 
277 1 Y 1 E LEU 141 ? D LEU 158 
278 1 Y 1 E VAL 142 ? D VAL 159 
279 1 Y 1 E LYS 143 ? D LYS 160 
280 1 Y 1 E ASP 144 ? D ASP 161 
281 1 Y 1 E TYR 145 ? D TYR 162 
282 1 Y 1 E PHE 146 ? D PHE 163 
283 1 Y 1 E PRO 147 ? D PRO 164 
284 1 Y 1 E GLU 148 ? D GLU 165 
285 1 Y 1 E PRO 149 ? D PRO 166 
286 1 Y 1 E VAL 150 ? D VAL 167 
287 1 Y 1 E THR 151 ? D THR 168 
288 1 Y 1 E VAL 152 ? D VAL 169 
289 1 Y 1 E SER 153 ? D SER 170 
290 1 Y 1 E TRP 154 ? D TRP 171 
291 1 Y 1 E ASN 155 ? D ASN 172 
292 1 Y 1 E SER 156 ? D SER 173 
293 1 Y 1 E GLY 157 ? D GLY 174 
294 1 Y 1 E ALA 158 ? D ALA 175 
295 1 Y 1 E LEU 159 ? D LEU 176 
296 1 Y 1 E THR 160 ? D THR 177 
297 1 Y 1 E SER 161 ? D SER 178 
298 1 Y 1 E GLY 162 ? D GLY 179 
299 1 Y 1 E VAL 163 ? D VAL 180 
300 1 Y 1 E HIS 164 ? D HIS 181 
301 1 Y 1 E THR 165 ? D THR 182 
302 1 Y 1 E PHE 166 ? D PHE 183 
303 1 Y 1 E PRO 167 ? D PRO 184 
304 1 Y 1 E ALA 168 ? D ALA 185 
305 1 Y 1 E VAL 169 ? D VAL 186 
306 1 Y 1 E LEU 170 ? D LEU 187 
307 1 Y 1 E GLN 171 ? D GLN 188 
308 1 Y 1 E SER 172 ? D SER 189 
309 1 Y 1 E SER 173 ? D SER 190 
310 1 Y 1 E GLY 174 ? D GLY 191 
311 1 Y 1 E LEU 175 ? D LEU 192 
312 1 Y 1 E TYR 176 ? D TYR 193 
313 1 Y 1 E SER 177 ? D SER 194 
314 1 Y 1 E LEU 178 ? D LEU 195 
315 1 Y 1 E SER 179 ? D SER 196 
316 1 Y 1 E SER 180 ? D SER 197 
317 1 Y 1 E VAL 181 ? D VAL 198 
318 1 Y 1 E VAL 182 ? D VAL 199 
319 1 Y 1 E THR 183 ? D THR 200 
320 1 Y 1 E VAL 184 ? D VAL 201 
321 1 Y 1 E PRO 185 ? D PRO 202 
322 1 Y 1 E SER 186 ? D SER 203 
323 1 Y 1 E SER 187 ? D SER 204 
324 1 Y 1 E SER 188 ? D SER 205 
325 1 Y 1 E LEU 189 ? D LEU 206 
326 1 Y 1 E GLY 190 ? D GLY 207 
327 1 Y 1 E THR 191 ? D THR 208 
328 1 Y 1 E GLN 192 ? D GLN 209 
329 1 Y 1 E THR 193 ? D THR 210 
330 1 Y 1 E TYR 194 ? D TYR 211 
331 1 Y 1 E ILE 195 ? D ILE 212 
332 1 Y 1 E CYS 196 ? D CYS 213 
333 1 Y 1 E ASN 197 ? D ASN 214 
334 1 Y 1 E VAL 198 ? D VAL 215 
335 1 Y 1 E ASN 199 ? D ASN 216 
336 1 Y 1 E HIS 200 ? D HIS 217 
337 1 Y 1 E LYS 201 ? D LYS 218 
338 1 Y 1 E PRO 202 ? D PRO 219 
339 1 Y 1 E SER 203 ? D SER 220 
340 1 Y 1 E ASN 204 ? D ASN 221 
341 1 Y 1 E THR 205 ? D THR 222 
342 1 Y 1 E LYS 206 ? D LYS 223 
343 1 Y 1 E VAL 207 ? D VAL 224 
344 1 Y 1 E ASP 208 ? D ASP 225 
345 1 Y 1 E LYS 209 ? D LYS 226 
346 1 Y 1 E ARG 210 ? D ARG 227 
347 1 Y 1 E VAL 211 ? D VAL 228 
348 1 Y 1 E GLU 212 ? D GLU 229 
349 1 Y 1 E PRO 213 ? D PRO 230 
350 1 Y 1 E LYS 214 ? D LYS 231 
351 1 Y 1 E SER 215 ? D SER 232 
352 1 Y 1 F ASP 0   ? E ASP 1   
353 1 Y 1 F THR 109 ? E THR 111 
354 1 Y 1 F VAL 110 ? E VAL 112 
355 1 Y 1 F ALA 111 ? E ALA 113 
356 1 Y 1 F ALA 112 ? E ALA 114 
357 1 Y 1 F PRO 113 ? E PRO 115 
358 1 Y 1 F SER 114 ? E SER 116 
359 1 Y 1 F VAL 115 ? E VAL 117 
360 1 Y 1 F PHE 116 ? E PHE 118 
361 1 Y 1 F ILE 117 ? E ILE 119 
362 1 Y 1 F PHE 118 ? E PHE 120 
363 1 Y 1 F PRO 119 ? E PRO 121 
364 1 Y 1 F PRO 120 ? E PRO 122 
365 1 Y 1 F SER 121 ? E SER 123 
366 1 Y 1 F ASP 122 ? E ASP 124 
367 1 Y 1 F GLU 123 ? E GLU 125 
368 1 Y 1 F GLN 124 ? E GLN 126 
369 1 Y 1 F LEU 125 ? E LEU 127 
370 1 Y 1 F LYS 126 ? E LYS 128 
371 1 Y 1 F SER 127 ? E SER 129 
372 1 Y 1 F GLY 128 ? E GLY 130 
373 1 Y 1 F THR 129 ? E THR 131 
374 1 Y 1 F ALA 130 ? E ALA 132 
375 1 Y 1 F SER 131 ? E SER 133 
376 1 Y 1 F VAL 132 ? E VAL 134 
377 1 Y 1 F VAL 133 ? E VAL 135 
378 1 Y 1 F CYS 134 ? E CYS 136 
379 1 Y 1 F LEU 135 ? E LEU 137 
380 1 Y 1 F LEU 136 ? E LEU 138 
381 1 Y 1 F ASN 137 ? E ASN 139 
382 1 Y 1 F ASN 138 ? E ASN 140 
383 1 Y 1 F PHE 139 ? E PHE 141 
384 1 Y 1 F TYR 140 ? E TYR 142 
385 1 Y 1 F PRO 141 ? E PRO 143 
386 1 Y 1 F ARG 142 ? E ARG 144 
387 1 Y 1 F GLU 143 ? E GLU 145 
388 1 Y 1 F ALA 144 ? E ALA 146 
389 1 Y 1 F LYS 145 ? E LYS 147 
390 1 Y 1 F VAL 146 ? E VAL 148 
391 1 Y 1 F GLN 147 ? E GLN 149 
392 1 Y 1 F TRP 148 ? E TRP 150 
393 1 Y 1 F LYS 149 ? E LYS 151 
394 1 Y 1 F VAL 150 ? E VAL 152 
395 1 Y 1 F ASP 151 ? E ASP 153 
396 1 Y 1 F ASN 152 ? E ASN 154 
397 1 Y 1 F ALA 153 ? E ALA 155 
398 1 Y 1 F LEU 154 ? E LEU 156 
399 1 Y 1 F GLN 155 ? E GLN 157 
400 1 Y 1 F SER 156 ? E SER 158 
401 1 Y 1 F GLY 157 ? E GLY 159 
402 1 Y 1 F ASN 158 ? E ASN 160 
403 1 Y 1 F SER 159 ? E SER 161 
404 1 Y 1 F GLN 160 ? E GLN 162 
405 1 Y 1 F GLU 161 ? E GLU 163 
406 1 Y 1 F SER 162 ? E SER 164 
407 1 Y 1 F VAL 163 ? E VAL 165 
408 1 Y 1 F THR 164 ? E THR 166 
409 1 Y 1 F GLU 165 ? E GLU 167 
410 1 Y 1 F GLN 166 ? E GLN 168 
411 1 Y 1 F ASP 167 ? E ASP 169 
412 1 Y 1 F SER 168 ? E SER 170 
413 1 Y 1 F LYS 169 ? E LYS 171 
414 1 Y 1 F ASP 170 ? E ASP 172 
415 1 Y 1 F SER 171 ? E SER 173 
416 1 Y 1 F THR 172 ? E THR 174 
417 1 Y 1 F TYR 173 ? E TYR 175 
418 1 Y 1 F SER 174 ? E SER 176 
419 1 Y 1 F LEU 175 ? E LEU 177 
420 1 Y 1 F SER 176 ? E SER 178 
421 1 Y 1 F SER 177 ? E SER 179 
422 1 Y 1 F THR 178 ? E THR 180 
423 1 Y 1 F LEU 179 ? E LEU 181 
424 1 Y 1 F THR 180 ? E THR 182 
425 1 Y 1 F LEU 181 ? E LEU 183 
426 1 Y 1 F SER 182 ? E SER 184 
427 1 Y 1 F LYS 183 ? E LYS 185 
428 1 Y 1 F ALA 184 ? E ALA 186 
429 1 Y 1 F ASP 185 ? E ASP 187 
430 1 Y 1 F TYR 186 ? E TYR 188 
431 1 Y 1 F GLU 187 ? E GLU 189 
432 1 Y 1 F LYS 188 ? E LYS 190 
433 1 Y 1 F HIS 189 ? E HIS 191 
434 1 Y 1 F LYS 190 ? E LYS 192 
435 1 Y 1 F VAL 191 ? E VAL 193 
436 1 Y 1 F TYR 192 ? E TYR 194 
437 1 Y 1 F ALA 193 ? E ALA 195 
438 1 Y 1 F CYS 194 ? E CYS 196 
439 1 Y 1 F GLU 195 ? E GLU 197 
440 1 Y 1 F VAL 196 ? E VAL 198 
441 1 Y 1 F THR 197 ? E THR 199 
442 1 Y 1 F HIS 198 ? E HIS 200 
443 1 Y 1 F GLN 199 ? E GLN 201 
444 1 Y 1 F GLY 200 ? E GLY 202 
445 1 Y 1 F LEU 201 ? E LEU 203 
446 1 Y 1 F SER 202 ? E SER 204 
447 1 Y 1 F SER 203 ? E SER 205 
448 1 Y 1 F PRO 204 ? E PRO 206 
449 1 Y 1 F VAL 205 ? E VAL 207 
450 1 Y 1 F THR 206 ? E THR 208 
451 1 Y 1 F LYS 207 ? E LYS 209 
452 1 Y 1 F SER 208 ? E SER 210 
453 1 Y 1 F PHE 209 ? E PHE 211 
454 1 Y 1 F ASN 210 ? E ASN 212 
455 1 Y 1 F ARG 211 ? E ARG 213 
456 1 Y 1 F GLY 212 ? E GLY 214 
457 1 Y 1 F GLU 213 ? E GLU 215 
458 1 Y 1 F CYS 214 ? E CYS 216 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N  N N 1   
ALA CA   C  N S 2   
ALA C    C  N N 3   
ALA O    O  N N 4   
ALA CB   C  N N 5   
ALA OXT  O  N N 6   
ALA H    H  N N 7   
ALA H2   H  N N 8   
ALA HA   H  N N 9   
ALA HB1  H  N N 10  
ALA HB2  H  N N 11  
ALA HB3  H  N N 12  
ALA HXT  H  N N 13  
ARG N    N  N N 14  
ARG CA   C  N S 15  
ARG C    C  N N 16  
ARG O    O  N N 17  
ARG CB   C  N N 18  
ARG CG   C  N N 19  
ARG CD   C  N N 20  
ARG NE   N  N N 21  
ARG CZ   C  N N 22  
ARG NH1  N  N N 23  
ARG NH2  N  N N 24  
ARG OXT  O  N N 25  
ARG H    H  N N 26  
ARG H2   H  N N 27  
ARG HA   H  N N 28  
ARG HB2  H  N N 29  
ARG HB3  H  N N 30  
ARG HG2  H  N N 31  
ARG HG3  H  N N 32  
ARG HD2  H  N N 33  
ARG HD3  H  N N 34  
ARG HE   H  N N 35  
ARG HH11 H  N N 36  
ARG HH12 H  N N 37  
ARG HH21 H  N N 38  
ARG HH22 H  N N 39  
ARG HXT  H  N N 40  
ASN N    N  N N 41  
ASN CA   C  N S 42  
ASN C    C  N N 43  
ASN O    O  N N 44  
ASN CB   C  N N 45  
ASN CG   C  N N 46  
ASN OD1  O  N N 47  
ASN ND2  N  N N 48  
ASN OXT  O  N N 49  
ASN H    H  N N 50  
ASN H2   H  N N 51  
ASN HA   H  N N 52  
ASN HB2  H  N N 53  
ASN HB3  H  N N 54  
ASN HD21 H  N N 55  
ASN HD22 H  N N 56  
ASN HXT  H  N N 57  
ASP N    N  N N 58  
ASP CA   C  N S 59  
ASP C    C  N N 60  
ASP O    O  N N 61  
ASP CB   C  N N 62  
ASP CG   C  N N 63  
ASP OD1  O  N N 64  
ASP OD2  O  N N 65  
ASP OXT  O  N N 66  
ASP H    H  N N 67  
ASP H2   H  N N 68  
ASP HA   H  N N 69  
ASP HB2  H  N N 70  
ASP HB3  H  N N 71  
ASP HD2  H  N N 72  
ASP HXT  H  N N 73  
CA  CA   CA N N 74  
CYS N    N  N N 75  
CYS CA   C  N R 76  
CYS C    C  N N 77  
CYS O    O  N N 78  
CYS CB   C  N N 79  
CYS SG   S  N N 80  
CYS OXT  O  N N 81  
CYS H    H  N N 82  
CYS H2   H  N N 83  
CYS HA   H  N N 84  
CYS HB2  H  N N 85  
CYS HB3  H  N N 86  
CYS HG   H  N N 87  
CYS HXT  H  N N 88  
GLN N    N  N N 89  
GLN CA   C  N S 90  
GLN C    C  N N 91  
GLN O    O  N N 92  
GLN CB   C  N N 93  
GLN CG   C  N N 94  
GLN CD   C  N N 95  
GLN OE1  O  N N 96  
GLN NE2  N  N N 97  
GLN OXT  O  N N 98  
GLN H    H  N N 99  
GLN H2   H  N N 100 
GLN HA   H  N N 101 
GLN HB2  H  N N 102 
GLN HB3  H  N N 103 
GLN HG2  H  N N 104 
GLN HG3  H  N N 105 
GLN HE21 H  N N 106 
GLN HE22 H  N N 107 
GLN HXT  H  N N 108 
GLU N    N  N N 109 
GLU CA   C  N S 110 
GLU C    C  N N 111 
GLU O    O  N N 112 
GLU CB   C  N N 113 
GLU CG   C  N N 114 
GLU CD   C  N N 115 
GLU OE1  O  N N 116 
GLU OE2  O  N N 117 
GLU OXT  O  N N 118 
GLU H    H  N N 119 
GLU H2   H  N N 120 
GLU HA   H  N N 121 
GLU HB2  H  N N 122 
GLU HB3  H  N N 123 
GLU HG2  H  N N 124 
GLU HG3  H  N N 125 
GLU HE2  H  N N 126 
GLU HXT  H  N N 127 
GLY N    N  N N 128 
GLY CA   C  N N 129 
GLY C    C  N N 130 
GLY O    O  N N 131 
GLY OXT  O  N N 132 
GLY H    H  N N 133 
GLY H2   H  N N 134 
GLY HA2  H  N N 135 
GLY HA3  H  N N 136 
GLY HXT  H  N N 137 
HIS N    N  N N 138 
HIS CA   C  N S 139 
HIS C    C  N N 140 
HIS O    O  N N 141 
HIS CB   C  N N 142 
HIS CG   C  Y N 143 
HIS ND1  N  Y N 144 
HIS CD2  C  Y N 145 
HIS CE1  C  Y N 146 
HIS NE2  N  Y N 147 
HIS OXT  O  N N 148 
HIS H    H  N N 149 
HIS H2   H  N N 150 
HIS HA   H  N N 151 
HIS HB2  H  N N 152 
HIS HB3  H  N N 153 
HIS HD1  H  N N 154 
HIS HD2  H  N N 155 
HIS HE1  H  N N 156 
HIS HE2  H  N N 157 
HIS HXT  H  N N 158 
ILE N    N  N N 159 
ILE CA   C  N S 160 
ILE C    C  N N 161 
ILE O    O  N N 162 
ILE CB   C  N S 163 
ILE CG1  C  N N 164 
ILE CG2  C  N N 165 
ILE CD1  C  N N 166 
ILE OXT  O  N N 167 
ILE H    H  N N 168 
ILE H2   H  N N 169 
ILE HA   H  N N 170 
ILE HB   H  N N 171 
ILE HG12 H  N N 172 
ILE HG13 H  N N 173 
ILE HG21 H  N N 174 
ILE HG22 H  N N 175 
ILE HG23 H  N N 176 
ILE HD11 H  N N 177 
ILE HD12 H  N N 178 
ILE HD13 H  N N 179 
ILE HXT  H  N N 180 
LEU N    N  N N 181 
LEU CA   C  N S 182 
LEU C    C  N N 183 
LEU O    O  N N 184 
LEU CB   C  N N 185 
LEU CG   C  N N 186 
LEU CD1  C  N N 187 
LEU CD2  C  N N 188 
LEU OXT  O  N N 189 
LEU H    H  N N 190 
LEU H2   H  N N 191 
LEU HA   H  N N 192 
LEU HB2  H  N N 193 
LEU HB3  H  N N 194 
LEU HG   H  N N 195 
LEU HD11 H  N N 196 
LEU HD12 H  N N 197 
LEU HD13 H  N N 198 
LEU HD21 H  N N 199 
LEU HD22 H  N N 200 
LEU HD23 H  N N 201 
LEU HXT  H  N N 202 
LYS N    N  N N 203 
LYS CA   C  N S 204 
LYS C    C  N N 205 
LYS O    O  N N 206 
LYS CB   C  N N 207 
LYS CG   C  N N 208 
LYS CD   C  N N 209 
LYS CE   C  N N 210 
LYS NZ   N  N N 211 
LYS OXT  O  N N 212 
LYS H    H  N N 213 
LYS H2   H  N N 214 
LYS HA   H  N N 215 
LYS HB2  H  N N 216 
LYS HB3  H  N N 217 
LYS HG2  H  N N 218 
LYS HG3  H  N N 219 
LYS HD2  H  N N 220 
LYS HD3  H  N N 221 
LYS HE2  H  N N 222 
LYS HE3  H  N N 223 
LYS HZ1  H  N N 224 
LYS HZ2  H  N N 225 
LYS HZ3  H  N N 226 
LYS HXT  H  N N 227 
MET N    N  N N 228 
MET CA   C  N S 229 
MET C    C  N N 230 
MET O    O  N N 231 
MET CB   C  N N 232 
MET CG   C  N N 233 
MET SD   S  N N 234 
MET CE   C  N N 235 
MET OXT  O  N N 236 
MET H    H  N N 237 
MET H2   H  N N 238 
MET HA   H  N N 239 
MET HB2  H  N N 240 
MET HB3  H  N N 241 
MET HG2  H  N N 242 
MET HG3  H  N N 243 
MET HE1  H  N N 244 
MET HE2  H  N N 245 
MET HE3  H  N N 246 
MET HXT  H  N N 247 
NAG C1   C  N R 248 
NAG C2   C  N R 249 
NAG C3   C  N R 250 
NAG C4   C  N S 251 
NAG C5   C  N R 252 
NAG C6   C  N N 253 
NAG C7   C  N N 254 
NAG C8   C  N N 255 
NAG N2   N  N N 256 
NAG O1   O  N N 257 
NAG O3   O  N N 258 
NAG O4   O  N N 259 
NAG O5   O  N N 260 
NAG O6   O  N N 261 
NAG O7   O  N N 262 
NAG H1   H  N N 263 
NAG H2   H  N N 264 
NAG H3   H  N N 265 
NAG H4   H  N N 266 
NAG H5   H  N N 267 
NAG H61  H  N N 268 
NAG H62  H  N N 269 
NAG H81  H  N N 270 
NAG H82  H  N N 271 
NAG H83  H  N N 272 
NAG HN2  H  N N 273 
NAG HO1  H  N N 274 
NAG HO3  H  N N 275 
NAG HO4  H  N N 276 
NAG HO6  H  N N 277 
PHE N    N  N N 278 
PHE CA   C  N S 279 
PHE C    C  N N 280 
PHE O    O  N N 281 
PHE CB   C  N N 282 
PHE CG   C  Y N 283 
PHE CD1  C  Y N 284 
PHE CD2  C  Y N 285 
PHE CE1  C  Y N 286 
PHE CE2  C  Y N 287 
PHE CZ   C  Y N 288 
PHE OXT  O  N N 289 
PHE H    H  N N 290 
PHE H2   H  N N 291 
PHE HA   H  N N 292 
PHE HB2  H  N N 293 
PHE HB3  H  N N 294 
PHE HD1  H  N N 295 
PHE HD2  H  N N 296 
PHE HE1  H  N N 297 
PHE HE2  H  N N 298 
PHE HZ   H  N N 299 
PHE HXT  H  N N 300 
PRO N    N  N N 301 
PRO CA   C  N S 302 
PRO C    C  N N 303 
PRO O    O  N N 304 
PRO CB   C  N N 305 
PRO CG   C  N N 306 
PRO CD   C  N N 307 
PRO OXT  O  N N 308 
PRO H    H  N N 309 
PRO HA   H  N N 310 
PRO HB2  H  N N 311 
PRO HB3  H  N N 312 
PRO HG2  H  N N 313 
PRO HG3  H  N N 314 
PRO HD2  H  N N 315 
PRO HD3  H  N N 316 
PRO HXT  H  N N 317 
SER N    N  N N 318 
SER CA   C  N S 319 
SER C    C  N N 320 
SER O    O  N N 321 
SER CB   C  N N 322 
SER OG   O  N N 323 
SER OXT  O  N N 324 
SER H    H  N N 325 
SER H2   H  N N 326 
SER HA   H  N N 327 
SER HB2  H  N N 328 
SER HB3  H  N N 329 
SER HG   H  N N 330 
SER HXT  H  N N 331 
THR N    N  N N 332 
THR CA   C  N S 333 
THR C    C  N N 334 
THR O    O  N N 335 
THR CB   C  N R 336 
THR OG1  O  N N 337 
THR CG2  C  N N 338 
THR OXT  O  N N 339 
THR H    H  N N 340 
THR H2   H  N N 341 
THR HA   H  N N 342 
THR HB   H  N N 343 
THR HG1  H  N N 344 
THR HG21 H  N N 345 
THR HG22 H  N N 346 
THR HG23 H  N N 347 
THR HXT  H  N N 348 
TRP N    N  N N 349 
TRP CA   C  N S 350 
TRP C    C  N N 351 
TRP O    O  N N 352 
TRP CB   C  N N 353 
TRP CG   C  Y N 354 
TRP CD1  C  Y N 355 
TRP CD2  C  Y N 356 
TRP NE1  N  Y N 357 
TRP CE2  C  Y N 358 
TRP CE3  C  Y N 359 
TRP CZ2  C  Y N 360 
TRP CZ3  C  Y N 361 
TRP CH2  C  Y N 362 
TRP OXT  O  N N 363 
TRP H    H  N N 364 
TRP H2   H  N N 365 
TRP HA   H  N N 366 
TRP HB2  H  N N 367 
TRP HB3  H  N N 368 
TRP HD1  H  N N 369 
TRP HE1  H  N N 370 
TRP HE3  H  N N 371 
TRP HZ2  H  N N 372 
TRP HZ3  H  N N 373 
TRP HH2  H  N N 374 
TRP HXT  H  N N 375 
TYR N    N  N N 376 
TYR CA   C  N S 377 
TYR C    C  N N 378 
TYR O    O  N N 379 
TYR CB   C  N N 380 
TYR CG   C  Y N 381 
TYR CD1  C  Y N 382 
TYR CD2  C  Y N 383 
TYR CE1  C  Y N 384 
TYR CE2  C  Y N 385 
TYR CZ   C  Y N 386 
TYR OH   O  N N 387 
TYR OXT  O  N N 388 
TYR H    H  N N 389 
TYR H2   H  N N 390 
TYR HA   H  N N 391 
TYR HB2  H  N N 392 
TYR HB3  H  N N 393 
TYR HD1  H  N N 394 
TYR HD2  H  N N 395 
TYR HE1  H  N N 396 
TYR HE2  H  N N 397 
TYR HH   H  N N 398 
TYR HXT  H  N N 399 
VAL N    N  N N 400 
VAL CA   C  N S 401 
VAL C    C  N N 402 
VAL O    O  N N 403 
VAL CB   C  N N 404 
VAL CG1  C  N N 405 
VAL CG2  C  N N 406 
VAL OXT  O  N N 407 
VAL H    H  N N 408 
VAL H2   H  N N 409 
VAL HA   H  N N 410 
VAL HB   H  N N 411 
VAL HG11 H  N N 412 
VAL HG12 H  N N 413 
VAL HG13 H  N N 414 
VAL HG21 H  N N 415 
VAL HG22 H  N N 416 
VAL HG23 H  N N 417 
VAL HXT  H  N N 418 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
NAG C1  C2   sing N N 235 
NAG C1  O1   sing N N 236 
NAG C1  O5   sing N N 237 
NAG C1  H1   sing N N 238 
NAG C2  C3   sing N N 239 
NAG C2  N2   sing N N 240 
NAG C2  H2   sing N N 241 
NAG C3  C4   sing N N 242 
NAG C3  O3   sing N N 243 
NAG C3  H3   sing N N 244 
NAG C4  C5   sing N N 245 
NAG C4  O4   sing N N 246 
NAG C4  H4   sing N N 247 
NAG C5  C6   sing N N 248 
NAG C5  O5   sing N N 249 
NAG C5  H5   sing N N 250 
NAG C6  O6   sing N N 251 
NAG C6  H61  sing N N 252 
NAG C6  H62  sing N N 253 
NAG C7  C8   sing N N 254 
NAG C7  N2   sing N N 255 
NAG C7  O7   doub N N 256 
NAG C8  H81  sing N N 257 
NAG C8  H82  sing N N 258 
NAG C8  H83  sing N N 259 
NAG N2  HN2  sing N N 260 
NAG O1  HO1  sing N N 261 
NAG O3  HO3  sing N N 262 
NAG O4  HO4  sing N N 263 
NAG O6  HO6  sing N N 264 
PHE N   CA   sing N N 265 
PHE N   H    sing N N 266 
PHE N   H2   sing N N 267 
PHE CA  C    sing N N 268 
PHE CA  CB   sing N N 269 
PHE CA  HA   sing N N 270 
PHE C   O    doub N N 271 
PHE C   OXT  sing N N 272 
PHE CB  CG   sing N N 273 
PHE CB  HB2  sing N N 274 
PHE CB  HB3  sing N N 275 
PHE CG  CD1  doub Y N 276 
PHE CG  CD2  sing Y N 277 
PHE CD1 CE1  sing Y N 278 
PHE CD1 HD1  sing N N 279 
PHE CD2 CE2  doub Y N 280 
PHE CD2 HD2  sing N N 281 
PHE CE1 CZ   doub Y N 282 
PHE CE1 HE1  sing N N 283 
PHE CE2 CZ   sing Y N 284 
PHE CE2 HE2  sing N N 285 
PHE CZ  HZ   sing N N 286 
PHE OXT HXT  sing N N 287 
PRO N   CA   sing N N 288 
PRO N   CD   sing N N 289 
PRO N   H    sing N N 290 
PRO CA  C    sing N N 291 
PRO CA  CB   sing N N 292 
PRO CA  HA   sing N N 293 
PRO C   O    doub N N 294 
PRO C   OXT  sing N N 295 
PRO CB  CG   sing N N 296 
PRO CB  HB2  sing N N 297 
PRO CB  HB3  sing N N 298 
PRO CG  CD   sing N N 299 
PRO CG  HG2  sing N N 300 
PRO CG  HG3  sing N N 301 
PRO CD  HD2  sing N N 302 
PRO CD  HD3  sing N N 303 
PRO OXT HXT  sing N N 304 
SER N   CA   sing N N 305 
SER N   H    sing N N 306 
SER N   H2   sing N N 307 
SER CA  C    sing N N 308 
SER CA  CB   sing N N 309 
SER CA  HA   sing N N 310 
SER C   O    doub N N 311 
SER C   OXT  sing N N 312 
SER CB  OG   sing N N 313 
SER CB  HB2  sing N N 314 
SER CB  HB3  sing N N 315 
SER OG  HG   sing N N 316 
SER OXT HXT  sing N N 317 
THR N   CA   sing N N 318 
THR N   H    sing N N 319 
THR N   H2   sing N N 320 
THR CA  C    sing N N 321 
THR CA  CB   sing N N 322 
THR CA  HA   sing N N 323 
THR C   O    doub N N 324 
THR C   OXT  sing N N 325 
THR CB  OG1  sing N N 326 
THR CB  CG2  sing N N 327 
THR CB  HB   sing N N 328 
THR OG1 HG1  sing N N 329 
THR CG2 HG21 sing N N 330 
THR CG2 HG22 sing N N 331 
THR CG2 HG23 sing N N 332 
THR OXT HXT  sing N N 333 
TRP N   CA   sing N N 334 
TRP N   H    sing N N 335 
TRP N   H2   sing N N 336 
TRP CA  C    sing N N 337 
TRP CA  CB   sing N N 338 
TRP CA  HA   sing N N 339 
TRP C   O    doub N N 340 
TRP C   OXT  sing N N 341 
TRP CB  CG   sing N N 342 
TRP CB  HB2  sing N N 343 
TRP CB  HB3  sing N N 344 
TRP CG  CD1  doub Y N 345 
TRP CG  CD2  sing Y N 346 
TRP CD1 NE1  sing Y N 347 
TRP CD1 HD1  sing N N 348 
TRP CD2 CE2  doub Y N 349 
TRP CD2 CE3  sing Y N 350 
TRP NE1 CE2  sing Y N 351 
TRP NE1 HE1  sing N N 352 
TRP CE2 CZ2  sing Y N 353 
TRP CE3 CZ3  doub Y N 354 
TRP CE3 HE3  sing N N 355 
TRP CZ2 CH2  doub Y N 356 
TRP CZ2 HZ2  sing N N 357 
TRP CZ3 CH2  sing Y N 358 
TRP CZ3 HZ3  sing N N 359 
TRP CH2 HH2  sing N N 360 
TRP OXT HXT  sing N N 361 
TYR N   CA   sing N N 362 
TYR N   H    sing N N 363 
TYR N   H2   sing N N 364 
TYR CA  C    sing N N 365 
TYR CA  CB   sing N N 366 
TYR CA  HA   sing N N 367 
TYR C   O    doub N N 368 
TYR C   OXT  sing N N 369 
TYR CB  CG   sing N N 370 
TYR CB  HB2  sing N N 371 
TYR CB  HB3  sing N N 372 
TYR CG  CD1  doub Y N 373 
TYR CG  CD2  sing Y N 374 
TYR CD1 CE1  sing Y N 375 
TYR CD1 HD1  sing N N 376 
TYR CD2 CE2  doub Y N 377 
TYR CD2 HD2  sing N N 378 
TYR CE1 CZ   doub Y N 379 
TYR CE1 HE1  sing N N 380 
TYR CE2 CZ   sing Y N 381 
TYR CE2 HE2  sing N N 382 
TYR CZ  OH   sing N N 383 
TYR OH  HH   sing N N 384 
TYR OXT HXT  sing N N 385 
VAL N   CA   sing N N 386 
VAL N   H    sing N N 387 
VAL N   H2   sing N N 388 
VAL CA  C    sing N N 389 
VAL CA  CB   sing N N 390 
VAL CA  HA   sing N N 391 
VAL C   O    doub N N 392 
VAL C   OXT  sing N N 393 
VAL CB  CG1  sing N N 394 
VAL CB  CG2  sing N N 395 
VAL CB  HB   sing N N 396 
VAL CG1 HG11 sing N N 397 
VAL CG1 HG12 sing N N 398 
VAL CG1 HG13 sing N N 399 
VAL CG2 HG21 sing N N 400 
VAL CG2 HG22 sing N N 401 
VAL CG2 HG23 sing N N 402 
VAL OXT HXT  sing N N 403 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-04-17 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           8Z4E 
_em_admin.last_update        2025-01-22 
_em_admin.map_release_date   2025-01-22 
_em_admin.title              
'Structure of human 18_14D scFv and 1G01 scFv in complex with influenza virus neuraminidase from A/Yunan/DQ001/2016 (H5N6)' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          11320 
_em_entity_assembly_naturalsource.organism             'Influenza A virus (A/Yunan/DQ001/2016 (H5N6))' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          9606 
_em_entity_assembly_recombinant.organism             'Homo sapiens' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         60 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K2 BASE (4k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'            ? 1  1 ? ? ? ? 
'IMAGE ACQUISITION'             ? 2  ? ? 1 ? ? 
MASKING                         ? 3  ? ? ? ? ? 
'CTF CORRECTION'                ? 4  1 ? ? ? ? 
'LAYERLINE INDEXING'            ? 5  ? ? ? ? ? 
'DIFFRACTION INDEXING'          ? 6  ? ? ? ? ? 
'MODEL FITTING'                 ? 7  ? ? ? ? ? 
'MODEL REFINEMENT'              ? 8  ? ? ? ? ? 
OTHER                           ? 9  ? ? ? ? ? 
'INITIAL EULER ASSIGNMENT'      ? 10 1 ? ? ? ? 
'FINAL EULER ASSIGNMENT'        ? 11 1 ? ? ? ? 
CLASSIFICATION                  ? 12 1 ? ? ? ? 
RECONSTRUCTION                  ? 13 1 ? ? ? ? 
'VOLUME SELECTION'              ? 14 1 1 1 ? ? 
'SERIES ALIGNMENT'              ? 15 1 1 1 ? ? 
'MOLECULAR REPLACEMENT'         ? 16 1 1 1 ? ? 
'LATTICE DISTORTION CORRECTION' ? 17 1 1 1 ? ? 
'SYMMETRY DETERMINATION'        ? 18 1 1 1 ? ? 
'CRYSTALLOGRAPHY MERGING'       ? 19 1 1 1 ? ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'National Natural Science Foundation of China (NSFC)' 
_pdbx_audit_support.country                China 
_pdbx_audit_support.grant_number           32192452 
_pdbx_audit_support.ordinal                1 
# 
loop_
_pdbx_entity_branch_list.entity_id 
_pdbx_entity_branch_list.comp_id 
_pdbx_entity_branch_list.num 
_pdbx_entity_branch_list.hetero 
6 NAG 1 n 
6 NAG 2 n 
# 
_atom_sites.entry_id                    8Z4E 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C  
CA 
N  
O  
S  
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N  N   . ARG A 1 1   ? 122.551 82.437  126.316 1.00 65.89  ? 82  ARG A N   1 
ATOM   2    C  CA  . ARG A 1 1   ? 122.975 81.074  126.018 1.00 65.89  ? 82  ARG A CA  1 
ATOM   3    C  C   . ARG A 1 1   ? 124.389 80.810  126.526 1.00 65.89  ? 82  ARG A C   1 
ATOM   4    O  O   . ARG A 1 1   ? 124.601 79.952  127.382 1.00 65.89  ? 82  ARG A O   1 
ATOM   5    C  CB  . ARG A 1 1   ? 122.901 80.809  124.513 1.00 65.89  ? 82  ARG A CB  1 
ATOM   6    C  CG  . ARG A 1 1   ? 123.276 79.391  124.116 1.00 65.89  ? 82  ARG A CG  1 
ATOM   7    C  CD  . ARG A 1 1   ? 122.258 78.386  124.629 1.00 65.89  ? 82  ARG A CD  1 
ATOM   8    N  NE  . ARG A 1 1   ? 122.592 77.022  124.238 1.00 65.89  ? 82  ARG A NE  1 
ATOM   9    C  CZ  . ARG A 1 1   ? 123.385 76.216  124.931 1.00 65.89  ? 82  ARG A CZ  1 
ATOM   10   N  NH1 . ARG A 1 1   ? 123.947 76.607  126.063 1.00 65.89  ? 82  ARG A NH1 1 
ATOM   11   N  NH2 . ARG A 1 1   ? 123.619 74.988  124.478 1.00 65.89  ? 82  ARG A NH2 1 
ATOM   12   N  N   . THR A 1 2   ? 125.354 81.554  125.991 1.00 64.35  ? 83  THR A N   1 
ATOM   13   C  CA  . THR A 1 2   ? 126.755 81.408  126.352 1.00 64.35  ? 83  THR A CA  1 
ATOM   14   C  C   . THR A 1 2   ? 127.336 82.777  126.674 1.00 64.35  ? 83  THR A C   1 
ATOM   15   O  O   . THR A 1 2   ? 126.979 83.781  126.051 1.00 64.35  ? 83  THR A O   1 
ATOM   16   C  CB  . THR A 1 2   ? 127.556 80.744  125.219 1.00 64.35  ? 83  THR A CB  1 
ATOM   17   O  OG1 . THR A 1 2   ? 126.924 79.513  124.846 1.00 64.35  ? 83  THR A OG1 1 
ATOM   18   C  CG2 . THR A 1 2   ? 128.982 80.449  125.662 1.00 64.35  ? 83  THR A CG2 1 
ATOM   19   N  N   . PHE A 1 3   ? 128.227 82.810  127.662 1.00 62.21  ? 84  PHE A N   1 
ATOM   20   C  CA  . PHE A 1 3   ? 128.856 84.059  128.066 1.00 62.21  ? 84  PHE A CA  1 
ATOM   21   C  C   . PHE A 1 3   ? 129.661 84.657  126.918 1.00 62.21  ? 84  PHE A C   1 
ATOM   22   O  O   . PHE A 1 3   ? 130.333 83.950  126.162 1.00 62.21  ? 84  PHE A O   1 
ATOM   23   C  CB  . PHE A 1 3   ? 129.762 83.838  129.278 1.00 62.21  ? 84  PHE A CB  1 
ATOM   24   C  CG  . PHE A 1 3   ? 129.028 83.811  130.590 1.00 62.21  ? 84  PHE A CG  1 
ATOM   25   C  CD1 . PHE A 1 3   ? 127.650 83.934  130.634 1.00 62.21  ? 84  PHE A CD1 1 
ATOM   26   C  CD2 . PHE A 1 3   ? 129.720 83.668  131.781 1.00 62.21  ? 84  PHE A CD2 1 
ATOM   27   C  CE1 . PHE A 1 3   ? 126.976 83.911  131.839 1.00 62.21  ? 84  PHE A CE1 1 
ATOM   28   C  CE2 . PHE A 1 3   ? 129.052 83.645  132.989 1.00 62.21  ? 84  PHE A CE2 1 
ATOM   29   C  CZ  . PHE A 1 3   ? 127.678 83.766  133.018 1.00 62.21  ? 84  PHE A CZ  1 
ATOM   30   N  N   . LEU A 1 4   ? 129.585 85.979  126.794 1.00 57.34  ? 85  LEU A N   1 
ATOM   31   C  CA  . LEU A 1 4   ? 130.236 86.684  125.700 1.00 57.34  ? 85  LEU A CA  1 
ATOM   32   C  C   . LEU A 1 4   ? 131.747 86.678  125.885 1.00 57.34  ? 85  LEU A C   1 
ATOM   33   O  O   . LEU A 1 4   ? 132.248 86.845  127.001 1.00 57.34  ? 85  LEU A O   1 
ATOM   34   C  CB  . LEU A 1 4   ? 129.715 88.118  125.611 1.00 57.34  ? 85  LEU A CB  1 
ATOM   35   C  CG  . LEU A 1 4   ? 130.230 88.971  124.453 1.00 57.34  ? 85  LEU A CG  1 
ATOM   36   C  CD1 . LEU A 1 4   ? 129.104 89.780  123.841 1.00 57.34  ? 85  LEU A CD1 1 
ATOM   37   C  CD2 . LEU A 1 4   ? 131.327 89.894  124.941 1.00 57.34  ? 85  LEU A CD2 1 
ATOM   38   N  N   . ASN A 1 5   ? 132.470 86.487  124.785 1.00 58.68  ? 86  ASN A N   1 
ATOM   39   C  CA  . ASN A 1 5   ? 133.930 86.461  124.778 1.00 58.68  ? 86  ASN A CA  1 
ATOM   40   C  C   . ASN A 1 5   ? 134.415 87.515  123.787 1.00 58.68  ? 86  ASN A C   1 
ATOM   41   O  O   . ASN A 1 5   ? 134.089 87.461  122.598 1.00 58.68  ? 86  ASN A O   1 
ATOM   42   C  CB  . ASN A 1 5   ? 134.444 85.071  124.415 1.00 58.68  ? 86  ASN A CB  1 
ATOM   43   C  CG  . ASN A 1 5   ? 135.877 84.848  124.851 1.00 58.68  ? 86  ASN A CG  1 
ATOM   44   O  OD1 . ASN A 1 5   ? 136.566 85.781  125.261 1.00 58.68  ? 86  ASN A OD1 1 
ATOM   45   N  ND2 . ASN A 1 5   ? 136.335 83.604  124.764 1.00 58.68  ? 86  ASN A ND2 1 
ATOM   46   N  N   . LEU A 1 6   ? 135.195 88.475  124.283 1.00 60.46  ? 87  LEU A N   1 
ATOM   47   C  CA  . LEU A 1 6   ? 135.752 89.524  123.438 1.00 60.46  ? 87  LEU A CA  1 
ATOM   48   C  C   . LEU A 1 6   ? 136.930 89.005  122.624 1.00 60.46  ? 87  LEU A C   1 
ATOM   49   O  O   . LEU A 1 6   ? 138.087 89.160  123.027 1.00 60.46  ? 87  LEU A O   1 
ATOM   50   C  CB  . LEU A 1 6   ? 136.186 90.719  124.288 1.00 60.46  ? 87  LEU A CB  1 
ATOM   51   C  CG  . LEU A 1 6   ? 135.092 91.544  124.961 1.00 60.46  ? 87  LEU A CG  1 
ATOM   52   C  CD1 . LEU A 1 6   ? 135.688 92.785  125.591 1.00 60.46  ? 87  LEU A CD1 1 
ATOM   53   C  CD2 . LEU A 1 6   ? 134.043 91.935  123.939 1.00 60.46  ? 87  LEU A CD2 1 
ATOM   54   N  N   . THR A 1 7   ? 136.647 88.392  121.478 1.00 61.41  ? 88  THR A N   1 
ATOM   55   C  CA  . THR A 1 7   ? 137.685 87.879  120.595 1.00 61.41  ? 88  THR A CA  1 
ATOM   56   C  C   . THR A 1 7   ? 137.716 88.548  119.230 1.00 61.41  ? 88  THR A C   1 
ATOM   57   O  O   . THR A 1 7   ? 138.798 88.696  118.659 1.00 61.41  ? 88  THR A O   1 
ATOM   58   C  CB  . THR A 1 7   ? 137.521 86.365  120.396 1.00 61.41  ? 88  THR A CB  1 
ATOM   59   O  OG1 . THR A 1 7   ? 136.138 86.055  120.186 1.00 61.41  ? 88  THR A OG1 1 
ATOM   60   C  CG2 . THR A 1 7   ? 138.025 85.610  121.616 1.00 61.41  ? 88  THR A CG2 1 
ATOM   61   N  N   . LYS A 1 8   ? 136.568 88.950  118.694 1.00 62.17  ? 89  LYS A N   1 
ATOM   62   C  CA  . LYS A 1 8   ? 136.543 89.593  117.390 1.00 62.17  ? 89  LYS A CA  1 
ATOM   63   C  C   . LYS A 1 8   ? 137.152 90.992  117.481 1.00 62.17  ? 89  LYS A C   1 
ATOM   64   O  O   . LYS A 1 8   ? 136.912 91.713  118.453 1.00 62.17  ? 89  LYS A O   1 
ATOM   65   C  CB  . LYS A 1 8   ? 135.111 89.670  116.864 1.00 62.17  ? 89  LYS A CB  1 
ATOM   66   C  CG  . LYS A 1 8   ? 134.507 88.310  116.545 1.00 62.17  ? 89  LYS A CG  1 
ATOM   67   C  CD  . LYS A 1 8   ? 133.149 88.437  115.876 1.00 62.17  ? 89  LYS A CD  1 
ATOM   68   C  CE  . LYS A 1 8   ? 132.082 88.858  116.873 1.00 62.17  ? 89  LYS A CE  1 
ATOM   69   N  NZ  . LYS A 1 8   ? 130.726 88.881  116.262 1.00 62.17  ? 89  LYS A NZ  1 
ATOM   70   N  N   . PRO A 1 9   ? 137.944 91.402  116.489 1.00 62.30  ? 90  PRO A N   1 
ATOM   71   C  CA  . PRO A 1 9   ? 138.604 92.711  116.566 1.00 62.30  ? 90  PRO A CA  1 
ATOM   72   C  C   . PRO A 1 9   ? 137.702 93.855  116.134 1.00 62.30  ? 90  PRO A C   1 
ATOM   73   O  O   . PRO A 1 9   ? 136.516 93.656  115.852 1.00 62.30  ? 90  PRO A O   1 
ATOM   74   C  CB  . PRO A 1 9   ? 139.798 92.552  115.620 1.00 62.30  ? 90  PRO A CB  1 
ATOM   75   C  CG  . PRO A 1 9   ? 139.328 91.566  114.601 1.00 62.30  ? 90  PRO A CG  1 
ATOM   76   C  CD  . PRO A 1 9   ? 138.326 90.657  115.276 1.00 62.30  ? 90  PRO A CD  1 
ATOM   77   N  N   . LEU A 1 10  ? 138.261 95.060  116.081 1.00 63.09  ? 91  LEU A N   1 
ATOM   78   C  CA  . LEU A 1 10  ? 137.535 96.276  115.720 1.00 63.09  ? 91  LEU A CA  1 
ATOM   79   C  C   . LEU A 1 10  ? 138.108 96.783  114.398 1.00 63.09  ? 91  LEU A C   1 
ATOM   80   O  O   . LEU A 1 10  ? 139.106 97.504  114.375 1.00 63.09  ? 91  LEU A O   1 
ATOM   81   C  CB  . LEU A 1 10  ? 137.659 97.322  116.825 1.00 63.09  ? 91  LEU A CB  1 
ATOM   82   C  CG  . LEU A 1 10  ? 136.519 98.324  116.992 1.00 63.09  ? 91  LEU A CG  1 
ATOM   83   C  CD1 . LEU A 1 10  ? 135.332 97.651  117.649 1.00 63.09  ? 91  LEU A CD1 1 
ATOM   84   C  CD2 . LEU A 1 10  ? 136.976 99.521  117.806 1.00 63.09  ? 91  LEU A CD2 1 
ATOM   85   N  N   . CYS A 1 11  ? 137.468 96.406  113.293 1.00 66.85  ? 92  CYS A N   1 
ATOM   86   C  CA  . CYS A 1 11  ? 137.969 96.784  111.981 1.00 66.85  ? 92  CYS A CA  1 
ATOM   87   C  C   . CYS A 1 11  ? 137.594 98.232  111.664 1.00 66.85  ? 92  CYS A C   1 
ATOM   88   O  O   . CYS A 1 11  ? 136.816 98.877  112.373 1.00 66.85  ? 92  CYS A O   1 
ATOM   89   C  CB  . CYS A 1 11  ? 137.454 95.821  110.912 1.00 66.85  ? 92  CYS A CB  1 
ATOM   90   S  SG  . CYS A 1 11  ? 135.662 95.751  110.728 1.00 66.85  ? 92  CYS A SG  1 
ATOM   91   N  N   . GLU A 1 12  ? 138.164 98.747  110.577 1.00 64.45  ? 93  GLU A N   1 
ATOM   92   C  CA  . GLU A 1 12  ? 138.056 100.162 110.251 1.00 64.45  ? 93  GLU A CA  1 
ATOM   93   C  C   . GLU A 1 12  ? 136.635 100.544 109.847 1.00 64.45  ? 93  GLU A C   1 
ATOM   94   O  O   . GLU A 1 12  ? 135.935 99.799  109.156 1.00 64.45  ? 93  GLU A O   1 
ATOM   95   C  CB  . GLU A 1 12  ? 139.025 100.520 109.125 1.00 64.45  ? 93  GLU A CB  1 
ATOM   96   C  CG  . GLU A 1 12  ? 138.934 99.601  107.916 1.00 64.45  ? 93  GLU A CG  1 
ATOM   97   C  CD  . GLU A 1 12  ? 139.798 100.067 106.761 1.00 64.45  ? 93  GLU A CD  1 
ATOM   98   O  OE1 . GLU A 1 12  ? 140.525 101.070 106.924 1.00 64.45  ? 93  GLU A OE1 1 
ATOM   99   O  OE2 . GLU A 1 12  ? 139.751 99.428  105.688 1.00 64.45  ? 93  GLU A OE2 1 
ATOM   100  N  N   . VAL A 1 13  ? 136.217 101.727 110.292 1.00 56.64  ? 94  VAL A N   1 
ATOM   101  C  CA  . VAL A 1 13  ? 134.973 102.354 109.865 1.00 56.64  ? 94  VAL A CA  1 
ATOM   102  C  C   . VAL A 1 13  ? 135.316 103.707 109.261 1.00 56.64  ? 94  VAL A C   1 
ATOM   103  O  O   . VAL A 1 13  ? 136.206 104.409 109.753 1.00 56.64  ? 94  VAL A O   1 
ATOM   104  C  CB  . VAL A 1 13  ? 133.969 102.505 111.028 1.00 56.64  ? 94  VAL A CB  1 
ATOM   105  C  CG1 . VAL A 1 13  ? 133.467 101.142 111.473 1.00 56.64  ? 94  VAL A CG1 1 
ATOM   106  C  CG2 . VAL A 1 13  ? 134.605 103.245 112.194 1.00 56.64  ? 94  VAL A CG2 1 
ATOM   107  N  N   . ASN A 1 14  ? 134.622 104.069 108.183 1.00 54.88  ? 95  ASN A N   1 
ATOM   108  C  CA  . ASN A 1 14  ? 134.960 105.257 107.410 1.00 54.88  ? 95  ASN A CA  1 
ATOM   109  C  C   . ASN A 1 14  ? 133.938 106.376 107.540 1.00 54.88  ? 95  ASN A C   1 
ATOM   110  O  O   . ASN A 1 14  ? 134.295 107.495 107.920 1.00 54.88  ? 95  ASN A O   1 
ATOM   111  C  CB  . ASN A 1 14  ? 135.132 104.880 105.933 1.00 54.88  ? 95  ASN A CB  1 
ATOM   112  C  CG  . ASN A 1 14  ? 136.516 104.350 105.627 1.00 54.88  ? 95  ASN A CG  1 
ATOM   113  O  OD1 . ASN A 1 14  ? 137.517 104.884 106.104 1.00 54.88  ? 95  ASN A OD1 1 
ATOM   114  N  ND2 . ASN A 1 14  ? 136.582 103.291 104.829 1.00 54.88  ? 95  ASN A ND2 1 
ATOM   115  N  N   . SER A 1 15  ? 132.673 106.110 107.233 1.00 53.95  ? 96  SER A N   1 
ATOM   116  C  CA  . SER A 1 15  ? 131.633 107.126 107.280 1.00 53.95  ? 96  SER A CA  1 
ATOM   117  C  C   . SER A 1 15  ? 130.470 106.627 108.122 1.00 53.95  ? 96  SER A C   1 
ATOM   118  O  O   . SER A 1 15  ? 130.093 105.455 108.043 1.00 53.95  ? 96  SER A O   1 
ATOM   119  C  CB  . SER A 1 15  ? 131.142 107.492 105.875 1.00 53.95  ? 96  SER A CB  1 
ATOM   120  O  OG  . SER A 1 15  ? 130.094 108.445 105.933 1.00 53.95  ? 96  SER A OG  1 
ATOM   121  N  N   . TRP A 1 16  ? 129.907 107.523 108.923 1.00 50.52  ? 97  TRP A N   1 
ATOM   122  C  CA  . TRP A 1 16  ? 128.806 107.184 109.809 1.00 50.52  ? 97  TRP A CA  1 
ATOM   123  C  C   . TRP A 1 16  ? 127.490 107.213 109.040 1.00 50.52  ? 97  TRP A C   1 
ATOM   124  O  O   . TRP A 1 16  ? 127.371 107.868 108.002 1.00 50.52  ? 97  TRP A O   1 
ATOM   125  C  CB  . TRP A 1 16  ? 128.763 108.149 110.993 1.00 50.52  ? 97  TRP A CB  1 
ATOM   126  C  CG  . TRP A 1 16  ? 130.080 108.234 111.712 1.00 50.52  ? 97  TRP A CG  1 
ATOM   127  C  CD1 . TRP A 1 16  ? 131.058 109.166 111.520 1.00 50.52  ? 97  TRP A CD1 1 
ATOM   128  C  CD2 . TRP A 1 16  ? 130.576 107.336 112.713 1.00 50.52  ? 97  TRP A CD2 1 
ATOM   129  N  NE1 . TRP A 1 16  ? 132.124 108.913 112.347 1.00 50.52  ? 97  TRP A NE1 1 
ATOM   130  C  CE2 . TRP A 1 16  ? 131.854 107.795 113.090 1.00 50.52  ? 97  TRP A CE2 1 
ATOM   131  C  CE3 . TRP A 1 16  ? 130.062 106.193 113.331 1.00 50.52  ? 97  TRP A CE3 1 
ATOM   132  C  CZ2 . TRP A 1 16  ? 132.622 107.153 114.055 1.00 50.52  ? 97  TRP A CZ2 1 
ATOM   133  C  CZ3 . TRP A 1 16  ? 130.827 105.557 114.289 1.00 50.52  ? 97  TRP A CZ3 1 
ATOM   134  C  CH2 . TRP A 1 16  ? 132.092 106.038 114.642 1.00 50.52  ? 97  TRP A CH2 1 
ATOM   135  N  N   . HIS A 1 17  ? 126.501 106.489 109.558 1.00 54.43  ? 98  HIS A N   1 
ATOM   136  C  CA  . HIS A 1 17  ? 125.245 106.271 108.856 1.00 54.43  ? 98  HIS A CA  1 
ATOM   137  C  C   . HIS A 1 17  ? 124.080 106.477 109.815 1.00 54.43  ? 98  HIS A C   1 
ATOM   138  O  O   . HIS A 1 17  ? 124.223 106.339 111.032 1.00 54.43  ? 98  HIS A O   1 
ATOM   139  C  CB  . HIS A 1 17  ? 125.187 104.856 108.255 1.00 54.43  ? 98  HIS A CB  1 
ATOM   140  C  CG  . HIS A 1 17  ? 124.169 104.687 107.169 1.00 54.43  ? 98  HIS A CG  1 
ATOM   141  N  ND1 . HIS A 1 17  ? 123.340 105.712 106.769 1.00 54.43  ? 98  HIS A ND1 1 
ATOM   142  C  CD2 . HIS A 1 17  ? 123.823 103.612 106.423 1.00 54.43  ? 98  HIS A CD2 1 
ATOM   143  C  CE1 . HIS A 1 17  ? 122.541 105.282 105.809 1.00 54.43  ? 98  HIS A CE1 1 
ATOM   144  N  NE2 . HIS A 1 17  ? 122.815 104.010 105.580 1.00 54.43  ? 98  HIS A NE2 1 
ATOM   145  N  N   . ILE A 1 18  ? 122.921 106.812 109.249 1.00 56.80  ? 99  ILE A N   1 
ATOM   146  C  CA  . ILE A 1 18  ? 121.723 107.028 110.048 1.00 56.80  ? 99  ILE A CA  1 
ATOM   147  C  C   . ILE A 1 18  ? 121.190 105.690 110.540 1.00 56.80  ? 99  ILE A C   1 
ATOM   148  O  O   . ILE A 1 18  ? 120.943 104.770 109.749 1.00 56.80  ? 99  ILE A O   1 
ATOM   149  C  CB  . ILE A 1 18  ? 120.661 107.778 109.231 1.00 56.80  ? 99  ILE A CB  1 
ATOM   150  C  CG1 . ILE A 1 18  ? 121.058 109.245 109.045 1.00 56.80  ? 99  ILE A CG1 1 
ATOM   151  C  CG2 . ILE A 1 18  ? 119.294 107.664 109.894 1.00 56.80  ? 99  ILE A CG2 1 
ATOM   152  C  CD1 . ILE A 1 18  ? 120.705 110.135 110.217 1.00 56.80  ? 99  ILE A CD1 1 
ATOM   153  N  N   . LEU A 1 19  ? 121.009 105.576 111.854 1.00 59.37  ? 100 LEU A N   1 
ATOM   154  C  CA  . LEU A 1 19  ? 120.349 104.416 112.439 1.00 59.37  ? 100 LEU A CA  1 
ATOM   155  C  C   . LEU A 1 19  ? 119.076 104.865 113.145 1.00 59.37  ? 100 LEU A C   1 
ATOM   156  O  O   . LEU A 1 19  ? 118.104 104.108 113.236 1.00 59.37  ? 100 LEU A O   1 
ATOM   157  C  CB  . LEU A 1 19  ? 121.284 103.687 113.407 1.00 59.37  ? 100 LEU A CB  1 
ATOM   158  C  CG  . LEU A 1 19  ? 120.720 102.448 114.105 1.00 59.37  ? 100 LEU A CG  1 
ATOM   159  C  CD1 . LEU A 1 19  ? 120.276 101.416 113.080 1.00 59.37  ? 100 LEU A CD1 1 
ATOM   160  C  CD2 . LEU A 1 19  ? 121.741 101.854 115.061 1.00 59.37  ? 100 LEU A CD2 1 
ATOM   161  N  N   . SER A 1 20  ? 119.073 106.099 113.637 1.00 63.07  ? 101 SER A N   1 
ATOM   162  C  CA  . SER A 1 20  ? 117.903 106.669 114.292 1.00 63.07  ? 101 SER A CA  1 
ATOM   163  C  C   . SER A 1 20  ? 117.189 107.655 113.374 1.00 63.07  ? 101 SER A C   1 
ATOM   164  O  O   . SER A 1 20  ? 116.984 108.815 113.735 1.00 63.07  ? 101 SER A O   1 
ATOM   165  C  CB  . SER A 1 20  ? 118.300 107.361 115.596 1.00 63.07  ? 101 SER A CB  1 
ATOM   166  O  OG  . SER A 1 20  ? 117.160 107.646 116.387 1.00 63.07  ? 101 SER A OG  1 
ATOM   167  N  N   . ALA A 1 31  ? 100.163 106.102 126.215 1.00 97.34  ? 112 ALA A N   1 
ATOM   168  C  CA  . ALA A 1 31  ? 100.162 106.247 124.764 1.00 97.34  ? 112 ALA A CA  1 
ATOM   169  C  C   . ALA A 1 31  ? 100.910 107.506 124.341 1.00 97.34  ? 112 ALA A C   1 
ATOM   170  O  O   . ALA A 1 31  ? 100.633 108.081 123.288 1.00 97.34  ? 112 ALA A O   1 
ATOM   171  C  CB  . ALA A 1 31  ? 98.737  106.272 124.234 1.00 97.34  ? 112 ALA A CB  1 
ATOM   172  N  N   . HIS A 1 32  ? 101.859 107.930 125.169 1.00 95.44  ? 113 HIS A N   1 
ATOM   173  C  CA  . HIS A 1 32  ? 102.660 109.117 124.895 1.00 95.44  ? 113 HIS A CA  1 
ATOM   174  C  C   . HIS A 1 32  ? 104.025 108.927 125.546 1.00 95.44  ? 113 HIS A C   1 
ATOM   175  O  O   . HIS A 1 32  ? 104.250 107.962 126.285 1.00 95.44  ? 113 HIS A O   1 
ATOM   176  C  CB  . HIS A 1 32  ? 101.952 110.382 125.392 1.00 95.44  ? 113 HIS A CB  1 
ATOM   177  C  CG  . HIS A 1 32  ? 101.424 110.270 126.788 1.00 95.44  ? 113 HIS A CG  1 
ATOM   178  N  ND1 . HIS A 1 32  ? 102.188 110.558 127.898 1.00 95.44  ? 113 HIS A ND1 1 
ATOM   179  C  CD2 . HIS A 1 32  ? 100.207 109.901 127.254 1.00 95.44  ? 113 HIS A CD2 1 
ATOM   180  C  CE1 . HIS A 1 32  ? 101.465 110.371 128.988 1.00 95.44  ? 113 HIS A CE1 1 
ATOM   181  N  NE2 . HIS A 1 32  ? 100.259 109.973 128.625 1.00 95.44  ? 113 HIS A NE2 1 
ATOM   182  N  N   . ILE A 1 33  ? 104.938 109.854 125.277 1.00 92.30  ? 114 ILE A N   1 
ATOM   183  C  CA  . ILE A 1 33  ? 106.290 109.783 125.800 1.00 92.30  ? 114 ILE A CA  1 
ATOM   184  C  C   . ILE A 1 33  ? 106.320 110.407 127.189 1.00 92.30  ? 114 ILE A C   1 
ATOM   185  O  O   . ILE A 1 33  ? 105.490 111.248 127.546 1.00 92.30  ? 114 ILE A O   1 
ATOM   186  C  CB  . ILE A 1 33  ? 107.308 110.472 124.861 1.00 92.30  ? 114 ILE A CB  1 
ATOM   187  C  CG1 . ILE A 1 33  ? 107.131 111.991 124.897 1.00 92.30  ? 114 ILE A CG1 1 
ATOM   188  C  CG2 . ILE A 1 33  ? 107.156 109.952 123.440 1.00 92.30  ? 114 ILE A CG2 1 
ATOM   189  C  CD1 . ILE A 1 33  ? 108.301 112.756 124.317 1.00 92.30  ? 114 ILE A CD1 1 
ATOM   190  N  N   . LEU A 1 34  ? 107.290 109.981 127.988 1.00 84.71  ? 115 LEU A N   1 
ATOM   191  C  CA  . LEU A 1 34  ? 107.491 110.497 129.329 1.00 84.71  ? 115 LEU A CA  1 
ATOM   192  C  C   . LEU A 1 34  ? 108.638 111.504 129.320 1.00 84.71  ? 115 LEU A C   1 
ATOM   193  O  O   . LEU A 1 34  ? 109.238 111.789 128.280 1.00 84.71  ? 115 LEU A O   1 
ATOM   194  C  CB  . LEU A 1 34  ? 107.753 109.346 130.302 1.00 84.71  ? 115 LEU A CB  1 
ATOM   195  C  CG  . LEU A 1 34  ? 106.574 108.414 130.590 1.00 84.71  ? 115 LEU A CG  1 
ATOM   196  C  CD1 . LEU A 1 34  ? 107.014 107.245 131.458 1.00 84.71  ? 115 LEU A CD1 1 
ATOM   197  C  CD2 . LEU A 1 34  ? 105.435 109.177 131.249 1.00 84.71  ? 115 LEU A CD2 1 
ATOM   198  N  N   . VAL A 1 35  ? 108.951 112.056 130.491 1.00 78.76  ? 116 VAL A N   1 
ATOM   199  C  CA  . VAL A 1 35  ? 110.072 112.978 130.615 1.00 78.76  ? 116 VAL A CA  1 
ATOM   200  C  C   . VAL A 1 35  ? 111.348 112.155 130.705 1.00 78.76  ? 116 VAL A C   1 
ATOM   201  O  O   . VAL A 1 35  ? 111.778 111.768 131.798 1.00 78.76  ? 116 VAL A O   1 
ATOM   202  C  CB  . VAL A 1 35  ? 109.915 113.903 131.836 1.00 78.76  ? 116 VAL A CB  1 
ATOM   203  C  CG1 . VAL A 1 35  ? 111.017 114.951 131.850 1.00 78.76  ? 116 VAL A CG1 1 
ATOM   204  C  CG2 . VAL A 1 35  ? 108.544 114.561 131.827 1.00 78.76  ? 116 VAL A CG2 1 
ATOM   205  N  N   . THR A 1 36  ? 111.957 111.882 129.557 1.00 74.88  ? 117 THR A N   1 
ATOM   206  C  CA  . THR A 1 36  ? 113.129 111.026 129.467 1.00 74.88  ? 117 THR A CA  1 
ATOM   207  C  C   . THR A 1 36  ? 114.380 111.887 129.387 1.00 74.88  ? 117 THR A C   1 
ATOM   208  O  O   . THR A 1 36  ? 114.507 112.725 128.489 1.00 74.88  ? 117 THR A O   1 
ATOM   209  C  CB  . THR A 1 36  ? 113.043 110.106 128.248 1.00 74.88  ? 117 THR A CB  1 
ATOM   210  O  OG1 . THR A 1 36  ? 112.992 110.897 127.054 1.00 74.88  ? 117 THR A OG1 1 
ATOM   211  C  CG2 . THR A 1 36  ? 111.794 109.243 128.328 1.00 74.88  ? 117 THR A CG2 1 
ATOM   212  N  N   . ARG A 1 37  ? 115.299 111.675 130.324 1.00 68.66  ? 118 ARG A N   1 
ATOM   213  C  CA  . ARG A 1 37  ? 116.545 112.419 130.372 1.00 68.66  ? 118 ARG A CA  1 
ATOM   214  C  C   . ARG A 1 37  ? 117.680 111.436 130.620 1.00 68.66  ? 118 ARG A C   1 
ATOM   215  O  O   . ARG A 1 37  ? 117.478 110.350 131.170 1.00 68.66  ? 118 ARG A O   1 
ATOM   216  C  CB  . ARG A 1 37  ? 116.496 113.510 131.450 1.00 68.66  ? 118 ARG A CB  1 
ATOM   217  C  CG  . ARG A 1 37  ? 117.572 114.577 131.325 1.00 68.66  ? 118 ARG A CG  1 
ATOM   218  C  CD  . ARG A 1 37  ? 117.259 115.770 132.215 1.00 68.66  ? 118 ARG A CD  1 
ATOM   219  N  NE  . ARG A 1 37  ? 118.225 116.850 132.051 1.00 68.66  ? 118 ARG A NE  1 
ATOM   220  C  CZ  . ARG A 1 37  ? 119.269 117.045 132.844 1.00 68.66  ? 118 ARG A CZ  1 
ATOM   221  N  NH1 . ARG A 1 37  ? 119.511 116.253 133.876 1.00 68.66  ? 118 ARG A NH1 1 
ATOM   222  N  NH2 . ARG A 1 37  ? 120.090 118.062 132.598 1.00 68.66  ? 118 ARG A NH2 1 
ATOM   223  N  N   . GLU A 1 38  ? 118.881 111.827 130.202 1.00 67.81  ? 119 GLU A N   1 
ATOM   224  C  CA  . GLU A 1 38  ? 120.066 110.980 130.266 1.00 67.81  ? 119 GLU A CA  1 
ATOM   225  C  C   . GLU A 1 38  ? 119.857 109.615 129.601 1.00 67.81  ? 119 GLU A C   1 
ATOM   226  O  O   . GLU A 1 38  ? 120.027 108.576 130.241 1.00 67.81  ? 119 GLU A O   1 
ATOM   227  C  CB  . GLU A 1 38  ? 120.513 110.800 131.710 1.00 67.81  ? 119 GLU A CB  1 
ATOM   228  C  CG  . GLU A 1 38  ? 120.724 112.102 132.457 1.00 67.81  ? 119 GLU A CG  1 
ATOM   229  C  CD  . GLU A 1 38  ? 119.525 112.521 133.287 1.00 67.81  ? 119 GLU A CD  1 
ATOM   230  O  OE1 . GLU A 1 38  ? 118.603 111.702 133.473 1.00 67.81  ? 119 GLU A OE1 1 
ATOM   231  O  OE2 . GLU A 1 38  ? 119.512 113.675 133.765 1.00 67.81  ? 119 GLU A OE2 1 
ATOM   232  N  N   . PRO A 1 39  ? 119.488 109.585 128.314 1.00 65.94  ? 120 PRO A N   1 
ATOM   233  C  CA  . PRO A 1 39  ? 119.274 108.295 127.650 1.00 65.94  ? 120 PRO A CA  1 
ATOM   234  C  C   . PRO A 1 39  ? 120.532 107.754 126.988 1.00 65.94  ? 120 PRO A C   1 
ATOM   235  O  O   . PRO A 1 39  ? 121.248 108.490 126.302 1.00 65.94  ? 120 PRO A O   1 
ATOM   236  C  CB  . PRO A 1 39  ? 118.188 108.621 126.619 1.00 65.94  ? 120 PRO A CB  1 
ATOM   237  C  CG  . PRO A 1 39  ? 118.392 110.091 126.303 1.00 65.94  ? 120 PRO A CG  1 
ATOM   238  C  CD  . PRO A 1 39  ? 119.244 110.708 127.392 1.00 65.94  ? 120 PRO A CD  1 
ATOM   239  N  N   . TYR A 1 40  ? 120.814 106.469 127.191 1.00 63.16  ? 121 TYR A N   1 
ATOM   240  C  CA  . TYR A 1 40  ? 121.904 105.788 126.513 1.00 63.16  ? 121 TYR A CA  1 
ATOM   241  C  C   . TYR A 1 40  ? 121.375 104.539 125.811 1.00 63.16  ? 121 TYR A C   1 
ATOM   242  O  O   . TYR A 1 40  ? 120.171 104.275 125.775 1.00 63.16  ? 121 TYR A O   1 
ATOM   243  C  CB  . TYR A 1 40  ? 123.031 105.454 127.497 1.00 63.16  ? 121 TYR A CB  1 
ATOM   244  C  CG  . TYR A 1 40  ? 122.603 104.659 128.711 1.00 63.16  ? 121 TYR A CG  1 
ATOM   245  C  CD1 . TYR A 1 40  ? 122.389 105.287 129.930 1.00 63.16  ? 121 TYR A CD1 1 
ATOM   246  C  CD2 . TYR A 1 40  ? 122.419 103.285 128.642 1.00 63.16  ? 121 TYR A CD2 1 
ATOM   247  C  CE1 . TYR A 1 40  ? 122.000 104.572 131.042 1.00 63.16  ? 121 TYR A CE1 1 
ATOM   248  C  CE2 . TYR A 1 40  ? 122.029 102.562 129.750 1.00 63.16  ? 121 TYR A CE2 1 
ATOM   249  C  CZ  . TYR A 1 40  ? 121.821 103.210 130.947 1.00 63.16  ? 121 TYR A CZ  1 
ATOM   250  O  OH  . TYR A 1 40  ? 121.432 102.494 132.056 1.00 63.16  ? 121 TYR A OH  1 
ATOM   251  N  N   . LEU A 1 41  ? 122.291 103.759 125.240 1.00 61.64  ? 122 LEU A N   1 
ATOM   252  C  CA  . LEU A 1 41  ? 121.938 102.579 124.460 1.00 61.64  ? 122 LEU A CA  1 
ATOM   253  C  C   . LEU A 1 41  ? 122.717 101.375 124.966 1.00 61.64  ? 122 LEU A C   1 
ATOM   254  O  O   . LEU A 1 41  ? 123.899 101.496 125.304 1.00 61.64  ? 122 LEU A O   1 
ATOM   255  C  CB  . LEU A 1 41  ? 122.220 102.805 122.973 1.00 61.64  ? 122 LEU A CB  1 
ATOM   256  C  CG  . LEU A 1 41  ? 121.230 103.712 122.247 1.00 61.64  ? 122 LEU A CG  1 
ATOM   257  C  CD1 . LEU A 1 41  ? 121.851 104.278 120.992 1.00 61.64  ? 122 LEU A CD1 1 
ATOM   258  C  CD2 . LEU A 1 41  ? 119.976 102.937 121.909 1.00 61.64  ? 122 LEU A CD2 1 
ATOM   259  N  N   . SER A 1 42  ? 122.057 100.218 125.009 1.00 65.15  ? 123 SER A N   1 
ATOM   260  C  CA  . SER A 1 42  ? 122.685 98.984  125.457 1.00 65.15  ? 123 SER A CA  1 
ATOM   261  C  C   . SER A 1 42  ? 122.325 97.849  124.508 1.00 65.15  ? 123 SER A C   1 
ATOM   262  O  O   . SER A 1 42  ? 121.180 97.723  124.069 1.00 65.15  ? 123 SER A O   1 
ATOM   263  C  CB  . SER A 1 42  ? 122.267 98.621  126.888 1.00 65.15  ? 123 SER A CB  1 
ATOM   264  O  OG  . SER A 1 42  ? 123.108 97.614  127.425 1.00 65.15  ? 123 SER A OG  1 
ATOM   265  N  N   . CYS A 1 43  ? 123.313 97.012  124.215 1.00 63.97  ? 124 CYS A N   1 
ATOM   266  C  CA  . CYS A 1 43  ? 123.164 95.898  123.292 1.00 63.97  ? 124 CYS A CA  1 
ATOM   267  C  C   . CYS A 1 43  ? 122.787 94.629  124.047 1.00 63.97  ? 124 CYS A C   1 
ATOM   268  O  O   . CYS A 1 43  ? 123.020 94.495  125.251 1.00 63.97  ? 124 CYS A O   1 
ATOM   269  C  CB  . CYS A 1 43  ? 124.457 95.677  122.501 1.00 63.97  ? 124 CYS A CB  1 
ATOM   270  S  SG  . CYS A 1 43  ? 125.849 95.125  123.515 1.00 63.97  ? 124 CYS A SG  1 
ATOM   271  N  N   . ASP A 1 44  ? 122.201 93.689  123.314 1.00 62.49  ? 125 ASP A N   1 
ATOM   272  C  CA  . ASP A 1 44  ? 121.837 92.384  123.842 1.00 62.49  ? 125 ASP A CA  1 
ATOM   273  C  C   . ASP A 1 44  ? 121.685 91.432  122.666 1.00 62.49  ? 125 ASP A C   1 
ATOM   274  O  O   . ASP A 1 44  ? 121.663 91.872  121.511 1.00 62.49  ? 125 ASP A O   1 
ATOM   275  C  CB  . ASP A 1 44  ? 120.548 92.452  124.679 1.00 62.49  ? 125 ASP A CB  1 
ATOM   276  C  CG  . ASP A 1 44  ? 119.354 92.959  123.893 1.00 62.49  ? 125 ASP A CG  1 
ATOM   277  O  OD1 . ASP A 1 44  ? 119.532 93.431  122.754 1.00 62.49  ? 125 ASP A OD1 1 
ATOM   278  O  OD2 . ASP A 1 44  ? 118.226 92.884  124.423 1.00 62.49  ? 125 ASP A OD2 1 
ATOM   279  N  N   . PRO A 1 45  ? 121.603 90.122  122.919 1.00 59.95  ? 126 PRO A N   1 
ATOM   280  C  CA  . PRO A 1 45  ? 121.433 89.180  121.800 1.00 59.95  ? 126 PRO A CA  1 
ATOM   281  C  C   . PRO A 1 45  ? 120.222 89.466  120.930 1.00 59.95  ? 126 PRO A C   1 
ATOM   282  O  O   . PRO A 1 45  ? 120.238 89.140  119.736 1.00 59.95  ? 126 PRO A O   1 
ATOM   283  C  CB  . PRO A 1 45  ? 121.310 87.828  122.511 1.00 59.95  ? 126 PRO A CB  1 
ATOM   284  C  CG  . PRO A 1 45  ? 122.135 87.988  123.729 1.00 59.95  ? 126 PRO A CG  1 
ATOM   285  C  CD  . PRO A 1 45  ? 121.977 89.424  124.163 1.00 59.95  ? 126 PRO A CD  1 
ATOM   286  N  N   . GLN A 1 46  ? 119.168 90.068  121.484 1.00 61.89  ? 127 GLN A N   1 
ATOM   287  C  CA  . GLN A 1 46  ? 117.992 90.396  120.689 1.00 61.89  ? 127 GLN A CA  1 
ATOM   288  C  C   . GLN A 1 46  ? 118.194 91.617  119.799 1.00 61.89  ? 127 GLN A C   1 
ATOM   289  O  O   . GLN A 1 46  ? 117.399 91.821  118.875 1.00 61.89  ? 127 GLN A O   1 
ATOM   290  C  CB  . GLN A 1 46  ? 116.786 90.621  121.603 1.00 61.89  ? 127 GLN A CB  1 
ATOM   291  C  CG  . GLN A 1 46  ? 116.112 89.342  122.068 1.00 61.89  ? 127 GLN A CG  1 
ATOM   292  C  CD  . GLN A 1 46  ? 116.843 88.683  123.220 1.00 61.89  ? 127 GLN A CD  1 
ATOM   293  O  OE1 . GLN A 1 46  ? 117.680 89.303  123.875 1.00 61.89  ? 127 GLN A OE1 1 
ATOM   294  N  NE2 . GLN A 1 46  ? 116.531 87.417  123.472 1.00 61.89  ? 127 GLN A NE2 1 
ATOM   295  N  N   . GLY A 1 47  ? 119.221 92.423  120.044 1.00 63.53  ? 128 GLY A N   1 
ATOM   296  C  CA  . GLY A 1 47  ? 119.480 93.600  119.246 1.00 63.53  ? 128 GLY A CA  1 
ATOM   297  C  C   . GLY A 1 47  ? 120.055 94.711  120.099 1.00 63.53  ? 128 GLY A C   1 
ATOM   298  O  O   . GLY A 1 47  ? 121.064 94.534  120.780 1.00 63.53  ? 128 GLY A O   1 
ATOM   299  N  N   . CYS A 1 48  ? 119.404 95.870  120.051 1.00 62.13  ? 129 CYS A N   1 
ATOM   300  C  CA  . CYS A 1 48  ? 119.814 97.036  120.819 1.00 62.13  ? 129 CYS A CA  1 
ATOM   301  C  C   . CYS A 1 48  ? 118.588 97.729  121.397 1.00 62.13  ? 129 CYS A C   1 
ATOM   302  O  O   . CYS A 1 48  ? 117.552 97.834  120.733 1.00 62.13  ? 129 CYS A O   1 
ATOM   303  C  CB  . CYS A 1 48  ? 120.610 98.016  119.955 1.00 62.13  ? 129 CYS A CB  1 
ATOM   304  S  SG  . CYS A 1 48  ? 122.302 97.494  119.608 1.00 62.13  ? 129 CYS A SG  1 
ATOM   305  N  N   . ARG A 1 49  ? 118.712 98.198  122.637 1.00 63.53  ? 130 ARG A N   1 
ATOM   306  C  CA  . ARG A 1 49  ? 117.643 98.888  123.339 1.00 63.53  ? 130 ARG A CA  1 
ATOM   307  C  C   . ARG A 1 49  ? 118.138 100.234 123.848 1.00 63.53  ? 130 ARG A C   1 
ATOM   308  O  O   . ARG A 1 49  ? 119.345 100.465 123.975 1.00 63.53  ? 130 ARG A O   1 
ATOM   309  C  CB  . ARG A 1 49  ? 117.113 98.059  124.512 1.00 63.53  ? 130 ARG A CB  1 
ATOM   310  C  CG  . ARG A 1 49  ? 117.261 96.561  124.345 1.00 63.53  ? 130 ARG A CG  1 
ATOM   311  C  CD  . ARG A 1 49  ? 116.859 95.845  125.618 1.00 63.53  ? 130 ARG A CD  1 
ATOM   312  N  NE  . ARG A 1 49  ? 115.440 96.017  125.902 1.00 63.53  ? 130 ARG A NE  1 
ATOM   313  C  CZ  . ARG A 1 49  ? 114.469 95.322  125.327 1.00 63.53  ? 130 ARG A CZ  1 
ATOM   314  N  NH1 . ARG A 1 49  ? 114.728 94.387  124.428 1.00 63.53  ? 130 ARG A NH1 1 
ATOM   315  N  NH2 . ARG A 1 49  ? 113.206 95.573  125.660 1.00 63.53  ? 130 ARG A NH2 1 
ATOM   316  N  N   . MET A 1 50  ? 117.189 101.119 124.139 1.00 67.16  ? 131 MET A N   1 
ATOM   317  C  CA  . MET A 1 50  ? 117.468 102.467 124.617 1.00 67.16  ? 131 MET A CA  1 
ATOM   318  C  C   . MET A 1 50  ? 116.960 102.596 126.045 1.00 67.16  ? 131 MET A C   1 
ATOM   319  O  O   . MET A 1 50  ? 115.797 102.282 126.321 1.00 67.16  ? 131 MET A O   1 
ATOM   320  C  CB  . MET A 1 50  ? 116.803 103.508 123.719 1.00 67.16  ? 131 MET A CB  1 
ATOM   321  C  CG  . MET A 1 50  ? 117.140 104.943 124.073 1.00 67.16  ? 131 MET A CG  1 
ATOM   322  S  SD  . MET A 1 50  ? 116.330 106.120 122.973 1.00 67.16  ? 131 MET A SD  1 
ATOM   323  C  CE  . MET A 1 50  ? 117.265 105.871 121.467 1.00 67.16  ? 131 MET A CE  1 
ATOM   324  N  N   . PHE A 1 51  ? 117.826 103.063 126.941 1.00 68.41  ? 132 PHE A N   1 
ATOM   325  C  CA  . PHE A 1 51  ? 117.516 103.240 128.351 1.00 68.41  ? 132 PHE A CA  1 
ATOM   326  C  C   . PHE A 1 51  ? 117.460 104.725 128.684 1.00 68.41  ? 132 PHE A C   1 
ATOM   327  O  O   . PHE A 1 51  ? 118.266 105.518 128.188 1.00 68.41  ? 132 PHE A O   1 
ATOM   328  C  CB  . PHE A 1 51  ? 118.566 102.571 129.250 1.00 68.41  ? 132 PHE A CB  1 
ATOM   329  C  CG  . PHE A 1 51  ? 118.570 101.066 129.190 1.00 68.41  ? 132 PHE A CG  1 
ATOM   330  C  CD1 . PHE A 1 51  ? 118.868 100.396 128.016 1.00 68.41  ? 132 PHE A CD1 1 
ATOM   331  C  CD2 . PHE A 1 51  ? 118.300 100.323 130.327 1.00 68.41  ? 132 PHE A CD2 1 
ATOM   332  C  CE1 . PHE A 1 51  ? 118.878 99.016  127.972 1.00 68.41  ? 132 PHE A CE1 1 
ATOM   333  C  CE2 . PHE A 1 51  ? 118.310 98.942  130.290 1.00 68.41  ? 132 PHE A CE2 1 
ATOM   334  C  CZ  . PHE A 1 51  ? 118.599 98.288  129.111 1.00 68.41  ? 132 PHE A CZ  1 
ATOM   335  N  N   . ALA A 1 52  ? 116.508 105.100 129.534 1.00 68.88  ? 133 ALA A N   1 
ATOM   336  C  CA  . ALA A 1 52  ? 116.420 106.493 129.949 1.00 68.88  ? 133 ALA A CA  1 
ATOM   337  C  C   . ALA A 1 52  ? 115.819 106.578 131.344 1.00 68.88  ? 133 ALA A C   1 
ATOM   338  O  O   . ALA A 1 52  ? 115.080 105.693 131.780 1.00 68.88  ? 133 ALA A O   1 
ATOM   339  C  CB  . ALA A 1 52  ? 115.597 107.323 128.960 1.00 68.88  ? 133 ALA A CB  1 
ATOM   340  N  N   . LEU A 1 53  ? 116.135 107.673 132.029 1.00 69.48  ? 134 LEU A N   1 
ATOM   341  C  CA  . LEU A 1 53  ? 115.611 107.964 133.356 1.00 69.48  ? 134 LEU A CA  1 
ATOM   342  C  C   . LEU A 1 53  ? 114.341 108.792 133.230 1.00 69.48  ? 134 LEU A C   1 
ATOM   343  O  O   . LEU A 1 53  ? 114.326 109.813 132.534 1.00 69.48  ? 134 LEU A O   1 
ATOM   344  C  CB  . LEU A 1 53  ? 116.648 108.704 134.204 1.00 69.48  ? 134 LEU A CB  1 
ATOM   345  C  CG  . LEU A 1 53  ? 117.916 107.919 134.540 1.00 69.48  ? 134 LEU A CG  1 
ATOM   346  C  CD1 . LEU A 1 53  ? 119.132 108.821 134.574 1.00 69.48  ? 134 LEU A CD1 1 
ATOM   347  C  CD2 . LEU A 1 53  ? 117.736 107.242 135.883 1.00 69.48  ? 134 LEU A CD2 1 
ATOM   348  N  N   . SER A 1 54  ? 113.282 108.351 133.904 1.00 73.26  ? 135 SER A N   1 
ATOM   349  C  CA  . SER A 1 54  ? 111.985 109.001 133.841 1.00 73.26  ? 135 SER A CA  1 
ATOM   350  C  C   . SER A 1 54  ? 111.506 109.330 135.246 1.00 73.26  ? 135 SER A C   1 
ATOM   351  O  O   . SER A 1 54  ? 111.836 108.637 136.215 1.00 73.26  ? 135 SER A O   1 
ATOM   352  C  CB  . SER A 1 54  ? 110.948 108.120 133.132 1.00 73.26  ? 135 SER A CB  1 
ATOM   353  O  OG  . SER A 1 54  ? 110.657 106.963 133.896 1.00 73.26  ? 135 SER A OG  1 
ATOM   354  N  N   . GLN A 1 55  ? 110.719 110.399 135.339 1.00 76.62  ? 136 GLN A N   1 
ATOM   355  C  CA  . GLN A 1 55  ? 110.166 110.873 136.599 1.00 76.62  ? 136 GLN A CA  1 
ATOM   356  C  C   . GLN A 1 55  ? 108.814 110.253 136.922 1.00 76.62  ? 136 GLN A C   1 
ATOM   357  O  O   . GLN A 1 55  ? 108.210 110.618 137.935 1.00 76.62  ? 136 GLN A O   1 
ATOM   358  C  CB  . GLN A 1 55  ? 110.034 112.399 136.574 1.00 76.62  ? 136 GLN A CB  1 
ATOM   359  C  CG  . GLN A 1 55  ? 111.279 113.124 136.094 1.00 76.62  ? 136 GLN A CG  1 
ATOM   360  C  CD  . GLN A 1 55  ? 112.316 113.285 137.187 1.00 76.62  ? 136 GLN A CD  1 
ATOM   361  O  OE1 . GLN A 1 55  ? 113.517 113.168 136.941 1.00 76.62  ? 136 GLN A OE1 1 
ATOM   362  N  NE2 . GLN A 1 55  ? 111.857 113.556 138.403 1.00 76.62  ? 136 GLN A NE2 1 
ATOM   363  N  N   . GLY A 1 56  ? 108.325 109.339 136.091 1.00 79.88  ? 137 GLY A N   1 
ATOM   364  C  CA  . GLY A 1 56  ? 107.043 108.700 136.327 1.00 79.88  ? 137 GLY A CA  1 
ATOM   365  C  C   . GLY A 1 56  ? 105.882 109.426 135.677 1.00 79.88  ? 137 GLY A C   1 
ATOM   366  O  O   . GLY A 1 56  ? 105.805 110.654 135.716 1.00 79.88  ? 137 GLY A O   1 
ATOM   367  N  N   . PRO A 1 73  ? 111.393 112.118 142.757 1.00 79.55  ? 154 PRO A N   1 
ATOM   368  C  CA  . PRO A 1 73  ? 111.257 111.322 143.981 1.00 79.55  ? 154 PRO A CA  1 
ATOM   369  C  C   . PRO A 1 73  ? 111.219 109.823 143.704 1.00 79.55  ? 154 PRO A C   1 
ATOM   370  O  O   . PRO A 1 73  ? 111.642 109.030 144.546 1.00 79.55  ? 154 PRO A O   1 
ATOM   371  C  CB  . PRO A 1 73  ? 109.926 111.803 144.562 1.00 79.55  ? 154 PRO A CB  1 
ATOM   372  C  CG  . PRO A 1 73  ? 109.794 113.201 144.071 1.00 79.55  ? 154 PRO A CG  1 
ATOM   373  C  CD  . PRO A 1 73  ? 110.420 113.223 142.703 1.00 79.55  ? 154 PRO A CD  1 
ATOM   374  N  N   . PHE A 1 74  ? 110.714 109.444 142.534 1.00 79.43  ? 155 PHE A N   1 
ATOM   375  C  CA  . PHE A 1 74  ? 110.624 108.043 142.132 1.00 79.43  ? 155 PHE A CA  1 
ATOM   376  C  C   . PHE A 1 74  ? 111.143 107.881 140.706 1.00 79.43  ? 155 PHE A C   1 
ATOM   377  O  O   . PHE A 1 74  ? 110.507 107.268 139.848 1.00 79.43  ? 155 PHE A O   1 
ATOM   378  C  CB  . PHE A 1 74  ? 109.197 107.506 142.275 1.00 79.43  ? 155 PHE A CB  1 
ATOM   379  C  CG  . PHE A 1 74  ? 108.130 108.439 141.770 1.00 79.43  ? 155 PHE A CG  1 
ATOM   380  C  CD1 . PHE A 1 74  ? 107.659 109.475 142.563 1.00 79.43  ? 155 PHE A CD1 1 
ATOM   381  C  CD2 . PHE A 1 74  ? 107.581 108.266 140.511 1.00 79.43  ? 155 PHE A CD2 1 
ATOM   382  C  CE1 . PHE A 1 74  ? 106.674 110.328 142.103 1.00 79.43  ? 155 PHE A CE1 1 
ATOM   383  C  CE2 . PHE A 1 74  ? 106.593 109.114 140.047 1.00 79.43  ? 155 PHE A CE2 1 
ATOM   384  C  CZ  . PHE A 1 74  ? 106.140 110.147 140.844 1.00 79.43  ? 155 PHE A CZ  1 
ATOM   385  N  N   . ARG A 1 75  ? 112.318 108.452 140.446 1.00 73.80  ? 156 ARG A N   1 
ATOM   386  C  CA  . ARG A 1 75  ? 112.968 108.296 139.151 1.00 73.80  ? 156 ARG A CA  1 
ATOM   387  C  C   . ARG A 1 75  ? 113.276 106.828 138.891 1.00 73.80  ? 156 ARG A C   1 
ATOM   388  O  O   . ARG A 1 75  ? 113.709 106.104 139.793 1.00 73.80  ? 156 ARG A O   1 
ATOM   389  C  CB  . ARG A 1 75  ? 114.255 109.119 139.111 1.00 73.80  ? 156 ARG A CB  1 
ATOM   390  C  CG  . ARG A 1 75  ? 114.042 110.619 139.195 1.00 73.80  ? 156 ARG A CG  1 
ATOM   391  C  CD  . ARG A 1 75  ? 115.369 111.360 139.154 1.00 73.80  ? 156 ARG A CD  1 
ATOM   392  N  NE  . ARG A 1 75  ? 115.713 111.802 137.808 1.00 73.80  ? 156 ARG A NE  1 
ATOM   393  C  CZ  . ARG A 1 75  ? 116.789 112.515 137.507 1.00 73.80  ? 156 ARG A CZ  1 
ATOM   394  N  NH1 . ARG A 1 75  ? 117.654 112.887 138.437 1.00 73.80  ? 156 ARG A NH1 1 
ATOM   395  N  NH2 . ARG A 1 75  ? 117.004 112.864 136.242 1.00 73.80  ? 156 ARG A NH2 1 
ATOM   396  N  N   . ALA A 1 76  ? 113.053 106.385 137.656 1.00 73.24  ? 157 ALA A N   1 
ATOM   397  C  CA  . ALA A 1 76  ? 113.244 104.987 137.302 1.00 73.24  ? 157 ALA A CA  1 
ATOM   398  C  C   . ALA A 1 76  ? 113.774 104.862 135.882 1.00 73.24  ? 157 ALA A C   1 
ATOM   399  O  O   . ALA A 1 76  ? 113.500 105.702 135.022 1.00 73.24  ? 157 ALA A O   1 
ATOM   400  C  CB  . ALA A 1 76  ? 111.937 104.194 137.436 1.00 73.24  ? 157 ALA A CB  1 
ATOM   401  N  N   . LEU A 1 77  ? 114.537 103.798 135.643 1.00 69.53  ? 158 LEU A N   1 
ATOM   402  C  CA  . LEU A 1 77  ? 114.995 103.488 134.297 1.00 69.53  ? 158 LEU A CA  1 
ATOM   403  C  C   . LEU A 1 77  ? 113.912 102.770 133.510 1.00 69.53  ? 158 LEU A C   1 
ATOM   404  O  O   . LEU A 1 77  ? 113.221 101.887 134.026 1.00 69.53  ? 158 LEU A O   1 
ATOM   405  C  CB  . LEU A 1 77  ? 116.254 102.624 134.320 1.00 69.53  ? 158 LEU A CB  1 
ATOM   406  C  CG  . LEU A 1 77  ? 117.594 103.289 134.614 1.00 69.53  ? 158 LEU A CG  1 
ATOM   407  C  CD1 . LEU A 1 77  ? 117.686 103.698 136.065 1.00 69.53  ? 158 LEU A CD1 1 
ATOM   408  C  CD2 . LEU A 1 77  ? 118.714 102.333 134.237 1.00 69.53  ? 158 LEU A CD2 1 
ATOM   409  N  N   . ILE A 1 78  ? 113.772 103.159 132.249 1.00 71.47  ? 159 ILE A N   1 
ATOM   410  C  CA  . ILE A 1 78  ? 112.873 102.508 131.310 1.00 71.47  ? 159 ILE A CA  1 
ATOM   411  C  C   . ILE A 1 78  ? 113.661 102.227 130.041 1.00 71.47  ? 159 ILE A C   1 
ATOM   412  O  O   . ILE A 1 78  ? 114.358 103.112 129.529 1.00 71.47  ? 159 ILE A O   1 
ATOM   413  C  CB  . ILE A 1 78  ? 111.633 103.372 131.013 1.00 71.47  ? 159 ILE A CB  1 
ATOM   414  C  CG1 . ILE A 1 78  ? 110.723 103.432 132.240 1.00 71.47  ? 159 ILE A CG1 1 
ATOM   415  C  CG2 . ILE A 1 78  ? 110.870 102.822 129.827 1.00 71.47  ? 159 ILE A CG2 1 
ATOM   416  C  CD1 . ILE A 1 78  ? 109.499 104.294 132.048 1.00 71.47  ? 159 ILE A CD1 1 
ATOM   417  N  N   . SER A 1 79  ? 113.568 100.995 129.549 1.00 72.82  ? 160 SER A N   1 
ATOM   418  C  CA  . SER A 1 79  ? 114.261 100.565 128.344 1.00 72.82  ? 160 SER A CA  1 
ATOM   419  C  C   . SER A 1 79  ? 113.235 100.152 127.300 1.00 72.82  ? 160 SER A C   1 
ATOM   420  O  O   . SER A 1 79  ? 112.273 99.444  127.614 1.00 72.82  ? 160 SER A O   1 
ATOM   421  C  CB  . SER A 1 79  ? 115.220 99.410  128.641 1.00 72.82  ? 160 SER A CB  1 
ATOM   422  O  OG  . SER A 1 79  ? 114.516 98.256  129.064 1.00 72.82  ? 160 SER A OG  1 
ATOM   423  N  N   . TRP A 1 80  ? 113.445 100.598 126.066 1.00 72.05  ? 161 TRP A N   1 
ATOM   424  C  CA  . TRP A 1 80  ? 112.522 100.341 124.970 1.00 72.05  ? 161 TRP A CA  1 
ATOM   425  C  C   . TRP A 1 80  ? 113.294 99.947  123.719 1.00 72.05  ? 161 TRP A C   1 
ATOM   426  O  O   . TRP A 1 80  ? 114.496 100.196 123.592 1.00 72.05  ? 161 TRP A O   1 
ATOM   427  C  CB  . TRP A 1 80  ? 111.632 101.559 124.690 1.00 72.05  ? 161 TRP A CB  1 
ATOM   428  C  CG  . TRP A 1 80  ? 112.388 102.843 124.544 1.00 72.05  ? 161 TRP A CG  1 
ATOM   429  C  CD1 . TRP A 1 80  ? 113.136 103.241 123.475 1.00 72.05  ? 161 TRP A CD1 1 
ATOM   430  C  CD2 . TRP A 1 80  ? 112.463 103.902 125.502 1.00 72.05  ? 161 TRP A CD2 1 
ATOM   431  N  NE1 . TRP A 1 80  ? 113.673 104.483 123.710 1.00 72.05  ? 161 TRP A NE1 1 
ATOM   432  C  CE2 . TRP A 1 80  ? 113.275 104.910 124.949 1.00 72.05  ? 161 TRP A CE2 1 
ATOM   433  C  CE3 . TRP A 1 80  ? 111.923 104.095 126.776 1.00 72.05  ? 161 TRP A CE3 1 
ATOM   434  C  CZ2 . TRP A 1 80  ? 113.559 106.093 125.625 1.00 72.05  ? 161 TRP A CZ2 1 
ATOM   435  C  CZ3 . TRP A 1 80  ? 112.206 105.269 127.446 1.00 72.05  ? 161 TRP A CZ3 1 
ATOM   436  C  CH2 . TRP A 1 80  ? 113.015 106.254 126.869 1.00 72.05  ? 161 TRP A CH2 1 
ATOM   437  N  N   . GLU A 1 81  ? 112.582 99.321  122.788 1.00 71.63  ? 162 GLU A N   1 
ATOM   438  C  CA  . GLU A 1 81  ? 113.193 98.859  121.554 1.00 71.63  ? 162 GLU A CA  1 
ATOM   439  C  C   . GLU A 1 81  ? 113.568 100.038 120.667 1.00 71.63  ? 162 GLU A C   1 
ATOM   440  O  O   . GLU A 1 81  ? 113.033 101.142 120.801 1.00 71.63  ? 162 GLU A O   1 
ATOM   441  C  CB  . GLU A 1 81  ? 112.247 97.923  120.803 1.00 71.63  ? 162 GLU A CB  1 
ATOM   442  C  CG  . GLU A 1 81  ? 111.719 96.773  121.641 1.00 71.63  ? 162 GLU A CG  1 
ATOM   443  C  CD  . GLU A 1 81  ? 111.532 95.506  120.832 1.00 71.63  ? 162 GLU A CD  1 
ATOM   444  O  OE1 . GLU A 1 81  ? 111.462 94.416  121.438 1.00 71.63  ? 162 GLU A OE1 1 
ATOM   445  O  OE2 . GLU A 1 81  ? 111.452 95.601  119.590 1.00 71.63  ? 162 GLU A OE2 1 
ATOM   446  N  N   . MET A 1 82  ? 114.504 99.789  119.757 1.00 71.27  ? 163 MET A N   1 
ATOM   447  C  CA  . MET A 1 82  ? 114.942 100.820 118.830 1.00 71.27  ? 163 MET A CA  1 
ATOM   448  C  C   . MET A 1 82  ? 113.785 101.277 117.946 1.00 71.27  ? 163 MET A C   1 
ATOM   449  O  O   . MET A 1 82  ? 113.015 100.469 117.421 1.00 71.27  ? 163 MET A O   1 
ATOM   450  C  CB  . MET A 1 82  ? 116.092 100.295 117.970 1.00 71.27  ? 163 MET A CB  1 
ATOM   451  C  CG  . MET A 1 82  ? 116.724 101.339 117.078 1.00 71.27  ? 163 MET A CG  1 
ATOM   452  S  SD  . MET A 1 82  ? 117.557 102.624 118.021 1.00 71.27  ? 163 MET A SD  1 
ATOM   453  C  CE  . MET A 1 82  ? 117.531 103.962 116.834 1.00 71.27  ? 163 MET A CE  1 
ATOM   454  N  N   . GLY A 1 83  ? 113.667 102.593 117.788 1.00 73.28  ? 164 GLY A N   1 
ATOM   455  C  CA  . GLY A 1 83  ? 112.656 103.165 116.920 1.00 73.28  ? 164 GLY A CA  1 
ATOM   456  C  C   . GLY A 1 83  ? 111.318 103.418 117.583 1.00 73.28  ? 164 GLY A C   1 
ATOM   457  O  O   . GLY A 1 83  ? 110.753 104.508 117.449 1.00 73.28  ? 164 GLY A O   1 
ATOM   458  N  N   . GLN A 1 84  ? 110.799 102.421 118.297 1.00 74.20  ? 165 GLN A N   1 
ATOM   459  C  CA  . GLN A 1 84  ? 109.486 102.547 118.915 1.00 74.20  ? 165 GLN A CA  1 
ATOM   460  C  C   . GLN A 1 84  ? 109.485 103.638 119.981 1.00 74.20  ? 165 GLN A C   1 
ATOM   461  O  O   . GLN A 1 84  ? 110.444 103.803 120.740 1.00 74.20  ? 165 GLN A O   1 
ATOM   462  C  CB  . GLN A 1 84  ? 109.054 101.215 119.529 1.00 74.20  ? 165 GLN A CB  1 
ATOM   463  C  CG  . GLN A 1 84  ? 108.439 100.239 118.538 1.00 74.20  ? 165 GLN A CG  1 
ATOM   464  C  CD  . GLN A 1 84  ? 109.450 99.678  117.560 1.00 74.20  ? 165 GLN A CD  1 
ATOM   465  O  OE1 . GLN A 1 84  ? 110.417 99.027  117.955 1.00 74.20  ? 165 GLN A OE1 1 
ATOM   466  N  NE2 . GLN A 1 84  ? 109.232 99.927  116.274 1.00 74.20  ? 165 GLN A NE2 1 
ATOM   467  N  N   . ALA A 1 85  ? 108.388 104.388 120.028 1.00 80.40  ? 166 ALA A N   1 
ATOM   468  C  CA  . ALA A 1 85  ? 108.234 105.432 121.026 1.00 80.40  ? 166 ALA A CA  1 
ATOM   469  C  C   . ALA A 1 85  ? 108.017 104.817 122.409 1.00 80.40  ? 166 ALA A C   1 
ATOM   470  O  O   . ALA A 1 85  ? 107.477 103.714 122.529 1.00 80.40  ? 166 ALA A O   1 
ATOM   471  C  CB  . ALA A 1 85  ? 107.059 106.340 120.670 1.00 80.40  ? 166 ALA A CB  1 
ATOM   472  N  N   . PRO A 1 86  ? 108.430 105.512 123.476 1.00 80.34  ? 167 PRO A N   1 
ATOM   473  C  CA  . PRO A 1 86  ? 108.233 104.962 124.824 1.00 80.34  ? 167 PRO A CA  1 
ATOM   474  C  C   . PRO A 1 86  ? 106.775 104.990 125.250 1.00 80.34  ? 167 PRO A C   1 
ATOM   475  O  O   . PRO A 1 86  ? 106.224 106.055 125.545 1.00 80.34  ? 167 PRO A O   1 
ATOM   476  C  CB  . PRO A 1 86  ? 109.094 105.871 125.708 1.00 80.34  ? 167 PRO A CB  1 
ATOM   477  C  CG  . PRO A 1 86  ? 109.225 107.140 124.956 1.00 80.34  ? 167 PRO A CG  1 
ATOM   478  C  CD  . PRO A 1 86  ? 109.105 106.822 123.494 1.00 80.34  ? 167 PRO A CD  1 
ATOM   479  N  N   . SER A 1 87  ? 106.142 103.819 125.287 1.00 86.22  ? 168 SER A N   1 
ATOM   480  C  CA  . SER A 1 87  ? 104.750 103.692 125.680 1.00 86.22  ? 168 SER A CA  1 
ATOM   481  C  C   . SER A 1 87  ? 104.607 102.572 126.701 1.00 86.22  ? 168 SER A C   1 
ATOM   482  O  O   . SER A 1 87  ? 105.373 101.601 126.670 1.00 86.22  ? 168 SER A O   1 
ATOM   483  C  CB  . SER A 1 87  ? 103.856 103.409 124.464 1.00 86.22  ? 168 SER A CB  1 
ATOM   484  O  OG  . SER A 1 87  ? 103.726 104.560 123.648 1.00 86.22  ? 168 SER A OG  1 
ATOM   485  N  N   . PRO A 1 88  ? 103.639 102.672 127.614 1.00 84.81  ? 169 PRO A N   1 
ATOM   486  C  CA  . PRO A 1 88  ? 103.497 101.638 128.649 1.00 84.81  ? 169 PRO A CA  1 
ATOM   487  C  C   . PRO A 1 88  ? 102.930 100.328 128.123 1.00 84.81  ? 169 PRO A C   1 
ATOM   488  O  O   . PRO A 1 88  ? 101.982 99.786  128.699 1.00 84.81  ? 169 PRO A O   1 
ATOM   489  C  CB  . PRO A 1 88  ? 102.538 102.284 129.657 1.00 84.81  ? 169 PRO A CB  1 
ATOM   490  C  CG  . PRO A 1 88  ? 102.661 103.753 129.418 1.00 84.81  ? 169 PRO A CG  1 
ATOM   491  C  CD  . PRO A 1 88  ? 102.870 103.883 127.940 1.00 84.81  ? 169 PRO A CD  1 
ATOM   492  N  N   . TYR A 1 89  ? 103.493 99.811  127.030 1.00 87.76  ? 170 TYR A N   1 
ATOM   493  C  CA  . TYR A 1 89  ? 103.137 98.477  126.552 1.00 87.76  ? 170 TYR A CA  1 
ATOM   494  C  C   . TYR A 1 89  ? 104.326 97.624  126.139 1.00 87.76  ? 170 TYR A C   1 
ATOM   495  O  O   . TYR A 1 89  ? 104.208 96.394  126.163 1.00 87.76  ? 170 TYR A O   1 
ATOM   496  C  CB  . TYR A 1 89  ? 102.161 98.569  125.373 1.00 87.76  ? 170 TYR A CB  1 
ATOM   497  C  CG  . TYR A 1 89  ? 101.616 97.230  124.928 1.00 87.76  ? 170 TYR A CG  1 
ATOM   498  C  CD1 . TYR A 1 89  ? 100.654 96.567  125.678 1.00 87.76  ? 170 TYR A CD1 1 
ATOM   499  C  CD2 . TYR A 1 89  ? 102.066 96.628  123.760 1.00 87.76  ? 170 TYR A CD2 1 
ATOM   500  C  CE1 . TYR A 1 89  ? 100.154 95.342  125.278 1.00 87.76  ? 170 TYR A CE1 1 
ATOM   501  C  CE2 . TYR A 1 89  ? 101.572 95.403  123.352 1.00 87.76  ? 170 TYR A CE2 1 
ATOM   502  C  CZ  . TYR A 1 89  ? 100.616 94.765  124.114 1.00 87.76  ? 170 TYR A CZ  1 
ATOM   503  O  OH  . TYR A 1 89  ? 100.121 93.546  123.712 1.00 87.76  ? 170 TYR A OH  1 
ATOM   504  N  N   . ASN A 1 90  ? 105.465 98.210  125.774 1.00 87.83  ? 171 ASN A N   1 
ATOM   505  C  CA  . ASN A 1 90  ? 106.646 97.456  125.373 1.00 87.83  ? 171 ASN A CA  1 
ATOM   506  C  C   . ASN A 1 90  ? 107.877 97.820  126.193 1.00 87.83  ? 171 ASN A C   1 
ATOM   507  O  O   . ASN A 1 90  ? 109.003 97.588  125.740 1.00 87.83  ? 171 ASN A O   1 
ATOM   508  C  CB  . ASN A 1 90  ? 106.928 97.670  123.884 1.00 87.83  ? 171 ASN A CB  1 
ATOM   509  C  CG  . ASN A 1 90  ? 105.801 97.172  123.000 1.00 87.83  ? 171 ASN A CG  1 
ATOM   510  O  OD1 . ASN A 1 90  ? 105.144 97.955  122.313 1.00 87.83  ? 171 ASN A OD1 1 
ATOM   511  N  ND2 . ASN A 1 90  ? 105.573 95.864  123.011 1.00 87.83  ? 171 ASN A ND2 1 
ATOM   512  N  N   . THR A 1 91  ? 107.692 98.379  127.385 1.00 83.17  ? 172 THR A N   1 
ATOM   513  C  CA  . THR A 1 91  ? 108.788 98.857  128.211 1.00 83.17  ? 172 THR A CA  1 
ATOM   514  C  C   . THR A 1 91  ? 108.938 97.992  129.456 1.00 83.17  ? 172 THR A C   1 
ATOM   515  O  O   . THR A 1 91  ? 108.006 97.295  129.867 1.00 83.17  ? 172 THR A O   1 
ATOM   516  C  CB  . THR A 1 91  ? 108.567 100.315 128.622 1.00 83.17  ? 172 THR A CB  1 
ATOM   517  O  OG1 . THR A 1 91  ? 107.306 100.439 129.291 1.00 83.17  ? 172 THR A OG1 1 
ATOM   518  C  CG2 . THR A 1 91  ? 108.576 101.219 127.399 1.00 83.17  ? 172 THR A CG2 1 
ATOM   519  N  N   . ARG A 1 92  ? 110.127 98.048  130.053 1.00 77.10  ? 173 ARG A N   1 
ATOM   520  C  CA  . ARG A 1 92  ? 110.441 97.305  131.266 1.00 77.10  ? 173 ARG A CA  1 
ATOM   521  C  C   . ARG A 1 92  ? 111.364 98.142  132.137 1.00 77.10  ? 173 ARG A C   1 
ATOM   522  O  O   . ARG A 1 92  ? 112.300 98.770  131.632 1.00 77.10  ? 173 ARG A O   1 
ATOM   523  C  CB  . ARG A 1 92  ? 111.097 95.960  130.939 1.00 77.10  ? 173 ARG A CB  1 
ATOM   524  C  CG  . ARG A 1 92  ? 110.123 94.880  130.498 1.00 77.10  ? 173 ARG A CG  1 
ATOM   525  C  CD  . ARG A 1 92  ? 109.299 94.371  131.669 1.00 77.10  ? 173 ARG A CD  1 
ATOM   526  N  NE  . ARG A 1 92  ? 108.502 93.204  131.312 1.00 77.10  ? 173 ARG A NE  1 
ATOM   527  C  CZ  . ARG A 1 92  ? 108.967 91.963  131.273 1.00 77.10  ? 173 ARG A CZ  1 
ATOM   528  N  NH1 . ARG A 1 92  ? 110.227 91.687  131.567 1.00 77.10  ? 173 ARG A NH1 1 
ATOM   529  N  NH2 . ARG A 1 92  ? 108.146 90.973  130.932 1.00 77.10  ? 173 ARG A NH2 1 
ATOM   530  N  N   . VAL A 1 93  ? 111.101 98.149  133.440 1.00 69.31  ? 174 VAL A N   1 
ATOM   531  C  CA  . VAL A 1 93  ? 111.914 98.887  134.399 1.00 69.31  ? 174 VAL A CA  1 
ATOM   532  C  C   . VAL A 1 93  ? 113.033 97.981  134.897 1.00 69.31  ? 174 VAL A C   1 
ATOM   533  O  O   . VAL A 1 93  ? 112.824 96.784  135.125 1.00 69.31  ? 174 VAL A O   1 
ATOM   534  C  CB  . VAL A 1 93  ? 111.053 99.409  135.563 1.00 69.31  ? 174 VAL A CB  1 
ATOM   535  C  CG1 . VAL A 1 93  ? 110.367 98.261  136.292 1.00 69.31  ? 174 VAL A CG1 1 
ATOM   536  C  CG2 . VAL A 1 93  ? 111.894 100.234 136.527 1.00 69.31  ? 174 VAL A CG2 1 
ATOM   537  N  N   . GLU A 1 94  ? 114.232 98.546  135.043 1.00 66.99  ? 175 GLU A N   1 
ATOM   538  C  CA  . GLU A 1 94  ? 115.383 97.776  135.498 1.00 66.99  ? 175 GLU A CA  1 
ATOM   539  C  C   . GLU A 1 94  ? 115.640 97.965  136.990 1.00 66.99  ? 175 GLU A C   1 
ATOM   540  O  O   . GLU A 1 94  ? 115.630 96.993  137.751 1.00 66.99  ? 175 GLU A O   1 
ATOM   541  C  CB  . GLU A 1 94  ? 116.626 98.166  134.693 1.00 66.99  ? 175 GLU A CB  1 
ATOM   542  C  CG  . GLU A 1 94  ? 116.498 97.913  133.201 1.00 66.99  ? 175 GLU A CG  1 
ATOM   543  C  CD  . GLU A 1 94  ? 116.741 96.463  132.831 1.00 66.99  ? 175 GLU A CD  1 
ATOM   544  O  OE1 . GLU A 1 94  ? 117.393 95.747  133.620 1.00 66.99  ? 175 GLU A OE1 1 
ATOM   545  O  OE2 . GLU A 1 94  ? 116.278 96.039  131.752 1.00 66.99  ? 175 GLU A OE2 1 
ATOM   546  N  N   . CYS A 1 95  ? 115.866 99.203  137.420 1.00 65.08  ? 176 CYS A N   1 
ATOM   547  C  CA  . CYS A 1 95  ? 116.055 99.506  138.832 1.00 65.08  ? 176 CYS A CA  1 
ATOM   548  C  C   . CYS A 1 95  ? 115.749 100.979 139.066 1.00 65.08  ? 176 CYS A C   1 
ATOM   549  O  O   . CYS A 1 95  ? 115.625 101.768 138.126 1.00 65.08  ? 176 CYS A O   1 
ATOM   550  C  CB  . CYS A 1 95  ? 117.464 99.126  139.310 1.00 65.08  ? 176 CYS A CB  1 
ATOM   551  S  SG  . CYS A 1 95  ? 118.867 99.673  138.308 1.00 65.08  ? 176 CYS A SG  1 
ATOM   552  N  N   . ILE A 1 96  ? 115.630 101.337 140.342 1.00 64.64  ? 177 ILE A N   1 
ATOM   553  C  CA  . ILE A 1 96  ? 115.146 102.646 140.766 1.00 64.64  ? 177 ILE A CA  1 
ATOM   554  C  C   . ILE A 1 96  ? 116.334 103.490 141.201 1.00 64.64  ? 177 ILE A C   1 
ATOM   555  O  O   . ILE A 1 96  ? 117.174 103.034 141.987 1.00 64.64  ? 177 ILE A O   1 
ATOM   556  C  CB  . ILE A 1 96  ? 114.121 102.520 141.905 1.00 64.64  ? 177 ILE A CB  1 
ATOM   557  C  CG1 . ILE A 1 96  ? 113.023 101.523 141.530 1.00 64.64  ? 177 ILE A CG1 1 
ATOM   558  C  CG2 . ILE A 1 96  ? 113.521 103.878 142.237 1.00 64.64  ? 177 ILE A CG2 1 
ATOM   559  C  CD1 . ILE A 1 96  ? 112.217 101.927 140.319 1.00 64.64  ? 177 ILE A CD1 1 
ATOM   560  N  N   . GLY A 1 97  ? 116.402 104.714 140.693 1.00 61.27  ? 178 GLY A N   1 
ATOM   561  C  CA  . GLY A 1 97  ? 117.462 105.622 141.076 1.00 61.27  ? 178 GLY A CA  1 
ATOM   562  C  C   . GLY A 1 97  ? 117.563 106.772 140.095 1.00 61.27  ? 178 GLY A C   1 
ATOM   563  O  O   . GLY A 1 97  ? 116.744 106.913 139.185 1.00 61.27  ? 178 GLY A O   1 
ATOM   564  N  N   . TRP A 1 98  ? 118.594 107.591 140.302 1.00 59.32  ? 179 TRP A N   1 
ATOM   565  C  CA  . TRP A 1 98  ? 118.860 108.735 139.445 1.00 59.32  ? 179 TRP A CA  1 
ATOM   566  C  C   . TRP A 1 98  ? 120.173 108.638 138.680 1.00 59.32  ? 179 TRP A C   1 
ATOM   567  O  O   . TRP A 1 98  ? 120.325 109.328 137.665 1.00 59.32  ? 179 TRP A O   1 
ATOM   568  C  CB  . TRP A 1 98  ? 118.842 110.034 140.267 1.00 59.32  ? 179 TRP A CB  1 
ATOM   569  C  CG  . TRP A 1 98  ? 119.820 110.040 141.392 1.00 59.32  ? 179 TRP A CG  1 
ATOM   570  C  CD1 . TRP A 1 98  ? 119.585 109.672 142.684 1.00 59.32  ? 179 TRP A CD1 1 
ATOM   571  C  CD2 . TRP A 1 98  ? 121.197 110.415 141.326 1.00 59.32  ? 179 TRP A CD2 1 
ATOM   572  N  NE1 . TRP A 1 98  ? 120.729 109.805 143.430 1.00 59.32  ? 179 TRP A NE1 1 
ATOM   573  C  CE2 . TRP A 1 98  ? 121.735 110.258 142.619 1.00 59.32  ? 179 TRP A CE2 1 
ATOM   574  C  CE3 . TRP A 1 98  ? 122.029 110.873 140.300 1.00 59.32  ? 179 TRP A CE3 1 
ATOM   575  C  CZ2 . TRP A 1 98  ? 123.063 110.541 142.910 1.00 59.32  ? 179 TRP A CZ2 1 
ATOM   576  C  CZ3 . TRP A 1 98  ? 123.346 111.152 140.592 1.00 59.32  ? 179 TRP A CZ3 1 
ATOM   577  C  CH2 . TRP A 1 98  ? 123.851 110.983 141.884 1.00 59.32  ? 179 TRP A CH2 1 
ATOM   578  N  N   . SER A 1 99  ? 121.117 107.815 139.128 1.00 58.06  ? 180 SER A N   1 
ATOM   579  C  CA  . SER A 1 99  ? 122.306 107.484 138.355 1.00 58.06  ? 180 SER A CA  1 
ATOM   580  C  C   . SER A 1 99  ? 122.348 105.974 138.194 1.00 58.06  ? 180 SER A C   1 
ATOM   581  O  O   . SER A 1 99  ? 121.942 105.234 139.093 1.00 58.06  ? 180 SER A O   1 
ATOM   582  C  CB  . SER A 1 99  ? 123.590 107.987 139.024 1.00 58.06  ? 180 SER A CB  1 
ATOM   583  O  OG  . SER A 1 99  ? 124.671 107.984 138.110 1.00 58.06  ? 180 SER A OG  1 
ATOM   584  N  N   . SER A 1 100 ? 122.824 105.515 137.040 1.00 60.44  ? 181 SER A N   1 
ATOM   585  C  CA  . SER A 1 100 ? 122.659 104.106 136.716 1.00 60.44  ? 181 SER A CA  1 
ATOM   586  C  C   . SER A 1 100 ? 123.582 103.701 135.576 1.00 60.44  ? 181 SER A C   1 
ATOM   587  O  O   . SER A 1 100 ? 124.188 104.535 134.901 1.00 60.44  ? 181 SER A O   1 
ATOM   588  C  CB  . SER A 1 100 ? 121.206 103.804 136.350 1.00 60.44  ? 181 SER A CB  1 
ATOM   589  O  OG  . SER A 1 100 ? 120.847 104.467 135.151 1.00 60.44  ? 181 SER A OG  1 
ATOM   590  N  N   . THR A 1 101 ? 123.672 102.387 135.384 1.00 60.06  ? 182 THR A N   1 
ATOM   591  C  CA  . THR A 1 101 ? 124.358 101.770 134.257 1.00 60.06  ? 182 THR A CA  1 
ATOM   592  C  C   . THR A 1 101 ? 123.769 100.380 134.062 1.00 60.06  ? 182 THR A C   1 
ATOM   593  O  O   . THR A 1 101 ? 123.103 99.847  134.952 1.00 60.06  ? 182 THR A O   1 
ATOM   594  C  CB  . THR A 1 101 ? 125.873 101.700 134.479 1.00 60.06  ? 182 THR A CB  1 
ATOM   595  O  OG1 . THR A 1 101 ? 126.530 101.449 133.231 1.00 60.06  ? 182 THR A OG1 1 
ATOM   596  C  CG2 . THR A 1 101 ? 126.219 100.591 135.460 1.00 60.06  ? 182 THR A CG2 1 
ATOM   597  N  N   . SER A 1 102 ? 124.002 99.803  132.885 1.00 60.16  ? 183 SER A N   1 
ATOM   598  C  CA  . SER A 1 102 ? 123.458 98.482  132.599 1.00 60.16  ? 183 SER A CA  1 
ATOM   599  C  C   . SER A 1 102 ? 124.130 97.902  131.366 1.00 60.16  ? 183 SER A C   1 
ATOM   600  O  O   . SER A 1 102 ? 124.509 98.635  130.448 1.00 60.16  ? 183 SER A O   1 
ATOM   601  C  CB  . SER A 1 102 ? 121.941 98.532  132.389 1.00 60.16  ? 183 SER A CB  1 
ATOM   602  O  OG  . SER A 1 102 ? 121.437 97.259  132.024 1.00 60.16  ? 183 SER A OG  1 
ATOM   603  N  N   . CYS A 1 103 ? 124.268 96.577  131.353 1.00 62.48  ? 184 CYS A N   1 
ATOM   604  C  CA  . CYS A 1 103 ? 124.725 95.873  130.159 1.00 62.48  ? 184 CYS A CA  1 
ATOM   605  C  C   . CYS A 1 103 ? 124.363 94.398  130.280 1.00 62.48  ? 184 CYS A C   1 
ATOM   606  O  O   . CYS A 1 103 ? 123.584 93.996  131.148 1.00 62.48  ? 184 CYS A O   1 
ATOM   607  C  CB  . CYS A 1 103 ? 126.226 96.061  129.920 1.00 62.48  ? 184 CYS A CB  1 
ATOM   608  S  SG  . CYS A 1 103 ? 127.330 95.509  131.230 1.00 62.48  ? 184 CYS A SG  1 
ATOM   609  N  N   . HIS A 1 104 ? 124.933 93.592  129.385 1.00 60.83  ? 185 HIS A N   1 
ATOM   610  C  CA  . HIS A 1 104 ? 124.593 92.184  129.258 1.00 60.83  ? 185 HIS A CA  1 
ATOM   611  C  C   . HIS A 1 104 ? 125.870 91.361  129.168 1.00 60.83  ? 185 HIS A C   1 
ATOM   612  O  O   . HIS A 1 104 ? 126.911 91.852  128.726 1.00 60.83  ? 185 HIS A O   1 
ATOM   613  C  CB  . HIS A 1 104 ? 123.722 91.938  128.020 1.00 60.83  ? 185 HIS A CB  1 
ATOM   614  C  CG  . HIS A 1 104 ? 122.770 90.793  128.165 1.00 60.83  ? 185 HIS A CG  1 
ATOM   615  N  ND1 . HIS A 1 104 ? 123.087 89.509  127.781 1.00 60.83  ? 185 HIS A ND1 1 
ATOM   616  C  CD2 . HIS A 1 104 ? 121.503 90.741  128.640 1.00 60.83  ? 185 HIS A CD2 1 
ATOM   617  C  CE1 . HIS A 1 104 ? 122.060 88.713  128.019 1.00 60.83  ? 185 HIS A CE1 1 
ATOM   618  N  NE2 . HIS A 1 104 ? 121.086 89.437  128.540 1.00 60.83  ? 185 HIS A NE2 1 
ATOM   619  N  N   . ASP A 1 105 ? 125.779 90.097  129.590 1.00 62.07  ? 186 ASP A N   1 
ATOM   620  C  CA  . ASP A 1 105 ? 126.922 89.191  129.578 1.00 62.07  ? 186 ASP A CA  1 
ATOM   621  C  C   . ASP A 1 105 ? 126.709 87.974  128.686 1.00 62.07  ? 186 ASP A C   1 
ATOM   622  O  O   . ASP A 1 105 ? 127.536 87.055  128.704 1.00 62.07  ? 186 ASP A O   1 
ATOM   623  C  CB  . ASP A 1 105 ? 127.266 88.746  131.005 1.00 62.07  ? 186 ASP A CB  1 
ATOM   624  C  CG  . ASP A 1 105 ? 126.289 87.723  131.562 1.00 62.07  ? 186 ASP A CG  1 
ATOM   625  O  OD1 . ASP A 1 105 ? 125.152 87.620  131.056 1.00 62.07  ? 186 ASP A OD1 1 
ATOM   626  O  OD2 . ASP A 1 105 ? 126.664 87.015  132.521 1.00 62.07  ? 186 ASP A OD2 1 
ATOM   627  N  N   . GLY A 1 106 ? 125.629 87.940  127.910 1.00 62.39  ? 187 GLY A N   1 
ATOM   628  C  CA  . GLY A 1 106 ? 125.324 86.832  127.039 1.00 62.39  ? 187 GLY A CA  1 
ATOM   629  C  C   . GLY A 1 106 ? 124.249 85.901  127.558 1.00 62.39  ? 187 GLY A C   1 
ATOM   630  O  O   . GLY A 1 106 ? 123.577 85.244  126.755 1.00 62.39  ? 187 GLY A O   1 
ATOM   631  N  N   . ILE A 1 107 ? 124.072 85.827  128.876 1.00 62.89  ? 188 ILE A N   1 
ATOM   632  C  CA  . ILE A 1 107 ? 123.042 85.006  129.499 1.00 62.89  ? 188 ILE A CA  1 
ATOM   633  C  C   . ILE A 1 107 ? 122.050 85.860  130.281 1.00 62.89  ? 188 ILE A C   1 
ATOM   634  O  O   . ILE A 1 107 ? 120.839 85.614  130.250 1.00 62.89  ? 188 ILE A O   1 
ATOM   635  C  CB  . ILE A 1 107 ? 123.663 83.917  130.405 1.00 62.89  ? 188 ILE A CB  1 
ATOM   636  C  CG1 . ILE A 1 107 ? 124.217 82.772  129.553 1.00 62.89  ? 188 ILE A CG1 1 
ATOM   637  C  CG2 . ILE A 1 107 ? 122.648 83.390  131.411 1.00 62.89  ? 188 ILE A CG2 1 
ATOM   638  C  CD1 . ILE A 1 107 ? 124.712 81.590  130.358 1.00 62.89  ? 188 ILE A CD1 1 
ATOM   639  N  N   . SER A 1 108 ? 122.544 86.888  130.969 1.00 61.39  ? 189 SER A N   1 
ATOM   640  C  CA  . SER A 1 108 ? 121.713 87.709  131.834 1.00 61.39  ? 189 SER A CA  1 
ATOM   641  C  C   . SER A 1 108 ? 122.114 89.171  131.698 1.00 61.39  ? 189 SER A C   1 
ATOM   642  O  O   . SER A 1 108 ? 123.196 89.500  131.208 1.00 61.39  ? 189 SER A O   1 
ATOM   643  C  CB  . SER A 1 108 ? 121.827 87.266  133.294 1.00 61.39  ? 189 SER A CB  1 
ATOM   644  O  OG  . SER A 1 108 ? 121.521 85.889  133.432 1.00 61.39  ? 189 SER A OG  1 
ATOM   645  N  N   . ARG A 1 109 ? 121.218 90.049  132.139 1.00 63.00  ? 190 ARG A N   1 
ATOM   646  C  CA  . ARG A 1 109 ? 121.439 91.488  132.097 1.00 63.00  ? 190 ARG A CA  1 
ATOM   647  C  C   . ARG A 1 109 ? 121.738 91.999  133.499 1.00 63.00  ? 190 ARG A C   1 
ATOM   648  O  O   . ARG A 1 109 ? 120.985 91.724  134.440 1.00 63.00  ? 190 ARG A O   1 
ATOM   649  C  CB  . ARG A 1 109 ? 120.219 92.209  131.521 1.00 63.00  ? 190 ARG A CB  1 
ATOM   650  C  CG  . ARG A 1 109 ? 120.286 93.723  131.625 1.00 63.00  ? 190 ARG A CG  1 
ATOM   651  C  CD  . ARG A 1 109 ? 119.245 94.384  130.733 1.00 63.00  ? 190 ARG A CD  1 
ATOM   652  N  NE  . ARG A 1 109 ? 119.710 94.534  129.359 1.00 63.00  ? 190 ARG A NE  1 
ATOM   653  C  CZ  . ARG A 1 109 ? 120.611 95.421  128.962 1.00 63.00  ? 190 ARG A CZ  1 
ATOM   654  N  NH1 . ARG A 1 109 ? 121.170 96.268  129.811 1.00 63.00  ? 190 ARG A NH1 1 
ATOM   655  N  NH2 . ARG A 1 109 ? 120.959 95.462  127.679 1.00 63.00  ? 190 ARG A NH2 1 
ATOM   656  N  N   . MET A 1 110 ? 122.832 92.742  133.634 1.00 60.55  ? 191 MET A N   1 
ATOM   657  C  CA  . MET A 1 110 ? 123.237 93.317  134.908 1.00 60.55  ? 191 MET A CA  1 
ATOM   658  C  C   . MET A 1 110 ? 122.963 94.814  134.890 1.00 60.55  ? 191 MET A C   1 
ATOM   659  O  O   . MET A 1 110 ? 123.418 95.524  133.983 1.00 60.55  ? 191 MET A O   1 
ATOM   660  C  CB  . MET A 1 110 ? 124.717 93.038  135.185 1.00 60.55  ? 191 MET A CB  1 
ATOM   661  C  CG  . MET A 1 110 ? 125.235 93.540  136.531 1.00 60.55  ? 191 MET A CG  1 
ATOM   662  S  SD  . MET A 1 110 ? 125.682 95.286  136.585 1.00 60.55  ? 191 MET A SD  1 
ATOM   663  C  CE  . MET A 1 110 ? 127.192 95.274  135.622 1.00 60.55  ? 191 MET A CE  1 
ATOM   664  N  N   . SER A 1 111 ? 122.222 95.286  135.892 1.00 59.66  ? 192 SER A N   1 
ATOM   665  C  CA  . SER A 1 111 ? 121.879 96.694  136.023 1.00 59.66  ? 192 SER A CA  1 
ATOM   666  C  C   . SER A 1 111 ? 122.317 97.205  137.388 1.00 59.66  ? 192 SER A C   1 
ATOM   667  O  O   . SER A 1 111 ? 122.308 96.466  138.375 1.00 59.66  ? 192 SER A O   1 
ATOM   668  C  CB  . SER A 1 111 ? 120.373 96.919  135.842 1.00 59.66  ? 192 SER A CB  1 
ATOM   669  O  OG  . SER A 1 111 ? 119.878 96.197  134.730 1.00 59.66  ? 192 SER A OG  1 
ATOM   670  N  N   . ILE A 1 112 ? 122.708 98.475  137.438 1.00 57.39  ? 193 ILE A N   1 
ATOM   671  C  CA  . ILE A 1 112 ? 123.125 99.128  138.672 1.00 57.39  ? 193 ILE A CA  1 
ATOM   672  C  C   . ILE A 1 112 ? 122.437 100.482 138.746 1.00 57.39  ? 193 ILE A C   1 
ATOM   673  O  O   . ILE A 1 112 ? 122.485 101.257 137.785 1.00 57.39  ? 193 ILE A O   1 
ATOM   674  C  CB  . ILE A 1 112 ? 124.655 99.295  138.739 1.00 57.39  ? 193 ILE A CB  1 
ATOM   675  C  CG1 . ILE A 1 112 ? 125.326 97.962  139.067 1.00 57.39  ? 193 ILE A CG1 1 
ATOM   676  C  CG2 . ILE A 1 112 ? 125.036 100.351 139.761 1.00 57.39  ? 193 ILE A CG2 1 
ATOM   677  C  CD1 . ILE A 1 112 ? 126.834 98.013  139.014 1.00 57.39  ? 193 ILE A CD1 1 
ATOM   678  N  N   . CYS A 1 113 ? 121.795 100.767 139.878 1.00 58.28  ? 194 CYS A N   1 
ATOM   679  C  CA  . CYS A 1 113 ? 121.198 102.070 140.136 1.00 58.28  ? 194 CYS A CA  1 
ATOM   680  C  C   . CYS A 1 113 ? 121.681 102.604 141.477 1.00 58.28  ? 194 CYS A C   1 
ATOM   681  O  O   . CYS A 1 113 ? 122.163 101.856 142.326 1.00 58.28  ? 194 CYS A O   1 
ATOM   682  C  CB  . CYS A 1 113 ? 119.663 102.016 140.119 1.00 58.28  ? 194 CYS A CB  1 
ATOM   683  S  SG  . CYS A 1 113 ? 118.926 101.689 138.508 1.00 58.28  ? 194 CYS A SG  1 
ATOM   684  N  N   . ILE A 1 114 ? 121.566 103.919 141.651 1.00 58.29  ? 195 ILE A N   1 
ATOM   685  C  CA  . ILE A 1 114 ? 121.926 104.579 142.900 1.00 58.29  ? 195 ILE A CA  1 
ATOM   686  C  C   . ILE A 1 114 ? 120.698 105.302 143.434 1.00 58.29  ? 195 ILE A C   1 
ATOM   687  O  O   . ILE A 1 114 ? 120.120 106.145 142.740 1.00 58.29  ? 195 ILE A O   1 
ATOM   688  C  CB  . ILE A 1 114 ? 123.093 105.561 142.721 1.00 58.29  ? 195 ILE A CB  1 
ATOM   689  C  CG1 . ILE A 1 114 ? 124.361 104.805 142.342 1.00 58.29  ? 195 ILE A CG1 1 
ATOM   690  C  CG2 . ILE A 1 114 ? 123.311 106.371 143.990 1.00 58.29  ? 195 ILE A CG2 1 
ATOM   691  C  CD1 . ILE A 1 114 ? 125.423 105.686 141.770 1.00 58.29  ? 195 ILE A CD1 1 
ATOM   692  N  N   . SER A 1 115 ? 120.310 104.983 144.667 1.00 60.93  ? 196 SER A N   1 
ATOM   693  C  CA  . SER A 1 115 ? 119.149 105.583 145.305 1.00 60.93  ? 196 SER A CA  1 
ATOM   694  C  C   . SER A 1 115 ? 119.502 105.997 146.727 1.00 60.93  ? 196 SER A C   1 
ATOM   695  O  O   . SER A 1 115 ? 120.497 105.546 147.301 1.00 60.93  ? 196 SER A O   1 
ATOM   696  C  CB  . SER A 1 115 ? 117.953 104.623 145.319 1.00 60.93  ? 196 SER A CB  1 
ATOM   697  O  OG  . SER A 1 115 ? 118.087 103.657 146.346 1.00 60.93  ? 196 SER A OG  1 
ATOM   698  N  N   . GLY A 1 116 ? 118.668 106.869 147.289 1.00 59.55  ? 197 GLY A N   1 
ATOM   699  C  CA  . GLY A 1 116 ? 118.858 107.345 148.637 1.00 59.55  ? 197 GLY A CA  1 
ATOM   700  C  C   . GLY A 1 116 ? 119.211 108.817 148.684 1.00 59.55  ? 197 GLY A C   1 
ATOM   701  O  O   . GLY A 1 116 ? 119.367 109.476 147.651 1.00 59.55  ? 197 GLY A O   1 
ATOM   702  N  N   . PRO A 1 117 ? 119.336 109.364 149.890 1.00 56.62  ? 198 PRO A N   1 
ATOM   703  C  CA  . PRO A 1 117 ? 119.732 110.769 150.028 1.00 56.62  ? 198 PRO A CA  1 
ATOM   704  C  C   . PRO A 1 117 ? 121.142 111.005 149.507 1.00 56.62  ? 198 PRO A C   1 
ATOM   705  O  O   . PRO A 1 117 ? 121.928 110.077 149.303 1.00 56.62  ? 198 PRO A O   1 
ATOM   706  C  CB  . PRO A 1 117 ? 119.649 111.022 151.538 1.00 56.62  ? 198 PRO A CB  1 
ATOM   707  C  CG  . PRO A 1 117 ? 119.668 109.664 152.162 1.00 56.62  ? 198 PRO A CG  1 
ATOM   708  C  CD  . PRO A 1 117 ? 118.996 108.756 151.186 1.00 56.62  ? 198 PRO A CD  1 
ATOM   709  N  N   . ASN A 1 118 ? 121.450 112.285 149.286 1.00 56.85  ? 199 ASN A N   1 
ATOM   710  C  CA  . ASN A 1 118 ? 122.734 112.647 148.696 1.00 56.85  ? 199 ASN A CA  1 
ATOM   711  C  C   . ASN A 1 118 ? 123.898 112.232 149.588 1.00 56.85  ? 199 ASN A C   1 
ATOM   712  O  O   . ASN A 1 118 ? 124.918 111.734 149.097 1.00 56.85  ? 199 ASN A O   1 
ATOM   713  C  CB  . ASN A 1 118 ? 122.779 114.150 148.423 1.00 56.85  ? 199 ASN A CB  1 
ATOM   714  C  CG  . ASN A 1 118 ? 121.909 114.554 147.251 1.00 56.85  ? 199 ASN A CG  1 
ATOM   715  O  OD1 . ASN A 1 118 ? 122.280 114.364 146.094 1.00 56.85  ? 199 ASN A OD1 1 
ATOM   716  N  ND2 . ASN A 1 118 ? 120.743 115.116 147.546 1.00 56.85  ? 199 ASN A ND2 1 
ATOM   717  N  N   . ASN A 1 119 ? 123.767 112.427 150.901 1.00 58.31  ? 200 ASN A N   1 
ATOM   718  C  CA  . ASN A 1 119 ? 124.852 112.088 151.813 1.00 58.31  ? 200 ASN A CA  1 
ATOM   719  C  C   . ASN A 1 119 ? 124.864 110.617 152.210 1.00 58.31  ? 200 ASN A C   1 
ATOM   720  O  O   . ASN A 1 119 ? 125.822 110.180 152.858 1.00 58.31  ? 200 ASN A O   1 
ATOM   721  C  CB  . ASN A 1 119 ? 124.781 112.973 153.062 1.00 58.31  ? 200 ASN A CB  1 
ATOM   722  C  CG  . ASN A 1 119 ? 123.454 112.858 153.796 1.00 58.31  ? 200 ASN A CG  1 
ATOM   723  O  OD1 . ASN A 1 119 ? 122.967 111.761 154.068 1.00 58.31  ? 200 ASN A OD1 1 
ATOM   724  N  ND2 . ASN A 1 119 ? 122.865 114.001 154.124 1.00 58.31  ? 200 ASN A ND2 1 
ATOM   725  N  N   . ASN A 1 120 ? 123.841 109.850 151.844 1.00 64.19  ? 201 ASN A N   1 
ATOM   726  C  CA  . ASN A 1 120 ? 123.737 108.445 152.230 1.00 64.19  ? 201 ASN A CA  1 
ATOM   727  C  C   . ASN A 1 120 ? 123.305 107.605 151.031 1.00 64.19  ? 201 ASN A C   1 
ATOM   728  O  O   . ASN A 1 120 ? 122.409 106.764 151.120 1.00 64.19  ? 201 ASN A O   1 
ATOM   729  C  CB  . ASN A 1 120 ? 122.770 108.282 153.401 1.00 64.19  ? 201 ASN A CB  1 
ATOM   730  C  CG  . ASN A 1 120 ? 122.998 107.001 154.172 1.00 64.19  ? 201 ASN A CG  1 
ATOM   731  O  OD1 . ASN A 1 120 ? 123.969 106.283 153.933 1.00 64.19  ? 201 ASN A OD1 1 
ATOM   732  N  ND2 . ASN A 1 120 ? 122.104 106.708 155.109 1.00 64.19  ? 201 ASN A ND2 1 
ATOM   733  N  N   . ALA A 1 121 ? 123.944 107.833 149.888 1.00 60.34  ? 202 ALA A N   1 
ATOM   734  C  CA  . ALA A 1 121 ? 123.577 107.129 148.668 1.00 60.34  ? 202 ALA A CA  1 
ATOM   735  C  C   . ALA A 1 121 ? 124.012 105.668 148.726 1.00 60.34  ? 202 ALA A C   1 
ATOM   736  O  O   . ALA A 1 121 ? 125.075 105.332 149.253 1.00 60.34  ? 202 ALA A O   1 
ATOM   737  C  CB  . ALA A 1 121 ? 124.199 107.810 147.450 1.00 60.34  ? 202 ALA A CB  1 
ATOM   738  N  N   . SER A 1 122 ? 123.171 104.795 148.172 1.00 61.25  ? 203 SER A N   1 
ATOM   739  C  CA  . SER A 1 122 ? 123.443 103.366 148.113 1.00 61.25  ? 203 SER A CA  1 
ATOM   740  C  C   . SER A 1 122 ? 123.147 102.848 146.714 1.00 61.25  ? 203 SER A C   1 
ATOM   741  O  O   . SER A 1 122 ? 122.167 103.259 146.085 1.00 61.25  ? 203 SER A O   1 
ATOM   742  C  CB  . SER A 1 122 ? 122.609 102.595 149.142 1.00 61.25  ? 203 SER A CB  1 
ATOM   743  O  OG  . SER A 1 122 ? 121.226 102.846 148.967 1.00 61.25  ? 203 SER A OG  1 
ATOM   744  N  N   . ALA A 1 123 ? 123.985 101.931 146.235 1.00 57.86  ? 204 ALA A N   1 
ATOM   745  C  CA  . ALA A 1 123 ? 123.845 101.362 144.903 1.00 57.86  ? 204 ALA A CA  1 
ATOM   746  C  C   . ALA A 1 123 ? 123.234 99.970  144.996 1.00 57.86  ? 204 ALA A C   1 
ATOM   747  O  O   . ALA A 1 123 ? 123.733 99.114  145.731 1.00 57.86  ? 204 ALA A O   1 
ATOM   748  C  CB  . ALA A 1 123 ? 125.196 101.299 144.192 1.00 57.86  ? 204 ALA A CB  1 
ATOM   749  N  N   . VAL A 1 124 ? 122.160 99.752  144.245 1.00 58.28  ? 205 VAL A N   1 
ATOM   750  C  CA  . VAL A 1 124 ? 121.467 98.472  144.182 1.00 58.28  ? 205 VAL A CA  1 
ATOM   751  C  C   . VAL A 1 124 ? 121.737 97.852  142.818 1.00 58.28  ? 205 VAL A C   1 
ATOM   752  O  O   . VAL A 1 124 ? 121.638 98.532  141.787 1.00 58.28  ? 205 VAL A O   1 
ATOM   753  C  CB  . VAL A 1 124 ? 119.957 98.636  144.424 1.00 58.28  ? 205 VAL A CB  1 
ATOM   754  C  CG1 . VAL A 1 124 ? 119.272 97.280  144.441 1.00 58.28  ? 205 VAL A CG1 1 
ATOM   755  C  CG2 . VAL A 1 124 ? 119.707 99.383  145.725 1.00 58.28  ? 205 VAL A CG2 1 
ATOM   756  N  N   . VAL A 1 125 ? 122.079 96.565  142.814 1.00 57.21  ? 206 VAL A N   1 
ATOM   757  C  CA  . VAL A 1 125 ? 122.413 95.834  141.598 1.00 57.21  ? 206 VAL A CA  1 
ATOM   758  C  C   . VAL A 1 125 ? 121.327 94.797  141.351 1.00 57.21  ? 206 VAL A C   1 
ATOM   759  O  O   . VAL A 1 125 ? 120.948 94.051  142.263 1.00 57.21  ? 206 VAL A O   1 
ATOM   760  C  CB  . VAL A 1 125 ? 123.794 95.171  141.699 1.00 57.21  ? 206 VAL A CB  1 
ATOM   761  C  CG1 . VAL A 1 125 ? 124.202 94.592  140.356 1.00 57.21  ? 206 VAL A CG1 1 
ATOM   762  C  CG2 . VAL A 1 125 ? 124.822 96.172  142.194 1.00 57.21  ? 206 VAL A CG2 1 
ATOM   763  N  N   . TRP A 1 126 ? 120.826 94.757  140.122 1.00 59.80  ? 207 TRP A N   1 
ATOM   764  C  CA  . TRP A 1 126 ? 119.811 93.806  139.697 1.00 59.80  ? 207 TRP A CA  1 
ATOM   765  C  C   . TRP A 1 126 ? 120.370 92.859  138.643 1.00 59.80  ? 207 TRP A C   1 
ATOM   766  O  O   . TRP A 1 126 ? 121.095 93.266  137.727 1.00 59.80  ? 207 TRP A O   1 
ATOM   767  C  CB  . TRP A 1 126 ? 118.576 94.524  139.145 1.00 59.80  ? 207 TRP A CB  1 
ATOM   768  C  CG  . TRP A 1 126 ? 117.878 95.413  140.132 1.00 59.80  ? 207 TRP A CG  1 
ATOM   769  C  CD1 . TRP A 1 126 ? 118.444 96.361  140.932 1.00 59.80  ? 207 TRP A CD1 1 
ATOM   770  C  CD2 . TRP A 1 126 ? 116.472 95.447  140.404 1.00 59.80  ? 207 TRP A CD2 1 
ATOM   771  N  NE1 . TRP A 1 126 ? 117.481 96.973  141.694 1.00 59.80  ? 207 TRP A NE1 1 
ATOM   772  C  CE2 . TRP A 1 126 ? 116.261 96.432  141.387 1.00 59.80  ? 207 TRP A CE2 1 
ATOM   773  C  CE3 . TRP A 1 126 ? 115.373 94.735  139.916 1.00 59.80  ? 207 TRP A CE3 1 
ATOM   774  C  CZ2 . TRP A 1 126 ? 114.996 96.724  141.891 1.00 59.80  ? 207 TRP A CZ2 1 
ATOM   775  C  CZ3 . TRP A 1 126 ? 114.118 95.027  140.417 1.00 59.80  ? 207 TRP A CZ3 1 
ATOM   776  C  CH2 . TRP A 1 126 ? 113.940 96.012  141.394 1.00 59.80  ? 207 TRP A CH2 1 
ATOM   777  N  N   . TYR A 1 127 ? 120.011 91.584  138.784 1.00 61.43  ? 208 TYR A N   1 
ATOM   778  C  CA  . TYR A 1 127 ? 120.495 90.525  137.903 1.00 61.43  ? 208 TYR A CA  1 
ATOM   779  C  C   . TYR A 1 127 ? 119.310 89.624  137.586 1.00 61.43  ? 208 TYR A C   1 
ATOM   780  O  O   . TYR A 1 127 ? 118.760 88.985  138.488 1.00 61.43  ? 208 TYR A O   1 
ATOM   781  C  CB  . TYR A 1 127 ? 121.628 89.748  138.569 1.00 61.43  ? 208 TYR A CB  1 
ATOM   782  C  CG  . TYR A 1 127 ? 122.374 88.804  137.658 1.00 61.43  ? 208 TYR A CG  1 
ATOM   783  C  CD1 . TYR A 1 127 ? 121.970 87.484  137.512 1.00 61.43  ? 208 TYR A CD1 1 
ATOM   784  C  CD2 . TYR A 1 127 ? 123.492 89.229  136.954 1.00 61.43  ? 208 TYR A CD2 1 
ATOM   785  C  CE1 . TYR A 1 127 ? 122.656 86.616  136.685 1.00 61.43  ? 208 TYR A CE1 1 
ATOM   786  C  CE2 . TYR A 1 127 ? 124.181 88.371  136.124 1.00 61.43  ? 208 TYR A CE2 1 
ATOM   787  C  CZ  . TYR A 1 127 ? 123.762 87.065  135.995 1.00 61.43  ? 208 TYR A CZ  1 
ATOM   788  O  OH  . TYR A 1 127 ? 124.446 86.205  135.168 1.00 61.43  ? 208 TYR A OH  1 
ATOM   789  N  N   . ARG A 1 128 ? 118.921 89.580  136.311 1.00 61.75  ? 209 ARG A N   1 
ATOM   790  C  CA  . ARG A 1 128 ? 117.711 88.887  135.860 1.00 61.75  ? 209 ARG A CA  1 
ATOM   791  C  C   . ARG A 1 128 ? 116.466 89.406  136.577 1.00 61.75  ? 209 ARG A C   1 
ATOM   792  O  O   . ARG A 1 128 ? 115.570 88.641  136.938 1.00 61.75  ? 209 ARG A O   1 
ATOM   793  C  CB  . ARG A 1 128 ? 117.831 87.369  136.017 1.00 61.75  ? 209 ARG A CB  1 
ATOM   794  C  CG  . ARG A 1 128 ? 118.895 86.740  135.143 1.00 61.75  ? 209 ARG A CG  1 
ATOM   795  C  CD  . ARG A 1 128 ? 118.967 85.230  135.322 1.00 61.75  ? 209 ARG A CD  1 
ATOM   796  N  NE  . ARG A 1 128 ? 117.769 84.565  134.822 1.00 61.75  ? 209 ARG A NE  1 
ATOM   797  C  CZ  . ARG A 1 128 ? 116.861 83.974  135.586 1.00 61.75  ? 209 ARG A CZ  1 
ATOM   798  N  NH1 . ARG A 1 128 ? 116.994 83.918  136.901 1.00 61.75  ? 209 ARG A NH1 1 
ATOM   799  N  NH2 . ARG A 1 128 ? 115.796 83.417  135.016 1.00 61.75  ? 209 ARG A NH2 1 
ATOM   800  N  N   . GLY A 1 129 ? 116.407 90.720  136.782 1.00 59.44  ? 210 GLY A N   1 
ATOM   801  C  CA  . GLY A 1 129 ? 115.201 91.367  137.252 1.00 59.44  ? 210 GLY A CA  1 
ATOM   802  C  C   . GLY A 1 129 ? 114.952 91.328  138.744 1.00 59.44  ? 210 GLY A C   1 
ATOM   803  O  O   . GLY A 1 129 ? 113.856 91.707  139.176 1.00 59.44  ? 210 GLY A O   1 
ATOM   804  N  N   . ARG A 1 130 ? 115.916 90.884  139.549 1.00 61.54  ? 211 ARG A N   1 
ATOM   805  C  CA  . ARG A 1 130 ? 115.755 90.949  140.993 1.00 61.54  ? 211 ARG A CA  1 
ATOM   806  C  C   . ARG A 1 130 ? 117.025 91.501  141.625 1.00 61.54  ? 211 ARG A C   1 
ATOM   807  O  O   . ARG A 1 130 ? 118.124 91.283  141.100 1.00 61.54  ? 211 ARG A O   1 
ATOM   808  C  CB  . ARG A 1 130 ? 115.433 89.569  141.590 1.00 61.54  ? 211 ARG A CB  1 
ATOM   809  C  CG  . ARG A 1 130 ? 116.272 88.422  141.065 1.00 61.54  ? 211 ARG A CG  1 
ATOM   810  C  CD  . ARG A 1 130 ? 115.475 87.127  141.083 1.00 61.54  ? 211 ARG A CD  1 
ATOM   811  N  NE  . ARG A 1 130 ? 116.335 85.949  141.082 1.00 61.54  ? 211 ARG A NE  1 
ATOM   812  C  CZ  . ARG A 1 130 ? 116.980 85.491  140.018 1.00 61.54  ? 211 ARG A CZ  1 
ATOM   813  N  NH1 . ARG A 1 130 ? 116.886 86.090  138.843 1.00 61.54  ? 211 ARG A NH1 1 
ATOM   814  N  NH2 . ARG A 1 130 ? 117.738 84.404  140.137 1.00 61.54  ? 211 ARG A NH2 1 
ATOM   815  N  N   . PRO A 1 131 ? 116.914 92.215  142.746 1.00 59.10  ? 212 PRO A N   1 
ATOM   816  C  CA  . PRO A 1 131 ? 118.115 92.769  143.383 1.00 59.10  ? 212 PRO A CA  1 
ATOM   817  C  C   . PRO A 1 131 ? 119.003 91.673  143.948 1.00 59.10  ? 212 PRO A C   1 
ATOM   818  O  O   . PRO A 1 131 ? 118.527 90.678  144.501 1.00 59.10  ? 212 PRO A O   1 
ATOM   819  C  CB  . PRO A 1 131 ? 117.561 93.669  144.497 1.00 59.10  ? 212 PRO A CB  1 
ATOM   820  C  CG  . PRO A 1 131 ? 116.104 93.397  144.590 1.00 59.10  ? 212 PRO A CG  1 
ATOM   821  C  CD  . PRO A 1 131 ? 115.694 92.418  143.546 1.00 59.10  ? 212 PRO A CD  1 
ATOM   822  N  N   . VAL A 1 132 ? 120.312 91.866  143.801 1.00 58.11  ? 213 VAL A N   1 
ATOM   823  C  CA  . VAL A 1 132 ? 121.283 90.872  144.248 1.00 58.11  ? 213 VAL A CA  1 
ATOM   824  C  C   . VAL A 1 132 ? 122.375 91.443  145.139 1.00 58.11  ? 213 VAL A C   1 
ATOM   825  O  O   . VAL A 1 132 ? 122.992 90.683  145.908 1.00 58.11  ? 213 VAL A O   1 
ATOM   826  C  CB  . VAL A 1 132 ? 121.911 90.154  143.033 1.00 58.11  ? 213 VAL A CB  1 
ATOM   827  C  CG1 . VAL A 1 132 ? 120.882 89.266  142.352 1.00 58.11  ? 213 VAL A CG1 1 
ATOM   828  C  CG2 . VAL A 1 132 ? 122.460 91.173  142.051 1.00 58.11  ? 213 VAL A CG2 1 
ATOM   829  N  N   . THR A 1 133 ? 122.668 92.741  145.095 1.00 58.09  ? 214 THR A N   1 
ATOM   830  C  CA  . THR A 1 133 ? 123.766 93.297  145.872 1.00 58.09  ? 214 THR A CA  1 
ATOM   831  C  C   . THR A 1 133 ? 123.477 94.757  146.193 1.00 58.09  ? 214 THR A C   1 
ATOM   832  O  O   . THR A 1 133 ? 122.854 95.465  145.397 1.00 58.09  ? 214 THR A O   1 
ATOM   833  C  CB  . THR A 1 133 ? 125.100 93.185  145.119 1.00 58.09  ? 214 THR A CB  1 
ATOM   834  O  OG1 . THR A 1 133 ? 125.232 91.873  144.558 1.00 58.09  ? 214 THR A OG1 1 
ATOM   835  C  CG2 . THR A 1 133 ? 126.273 93.439  146.054 1.00 58.09  ? 214 THR A CG2 1 
ATOM   836  N  N   . GLU A 1 134 ? 123.932 95.195  147.366 1.00 58.61  ? 215 GLU A N   1 
ATOM   837  C  CA  . GLU A 1 134 ? 123.863 96.591  147.778 1.00 58.61  ? 215 GLU A CA  1 
ATOM   838  C  C   . GLU A 1 134 ? 125.259 97.050  148.170 1.00 58.61  ? 215 GLU A C   1 
ATOM   839  O  O   . GLU A 1 134 ? 125.946 96.372  148.943 1.00 58.61  ? 215 GLU A O   1 
ATOM   840  C  CB  . GLU A 1 134 ? 122.884 96.779  148.939 1.00 58.61  ? 215 GLU A CB  1 
ATOM   841  C  CG  . GLU A 1 134 ? 121.428 96.529  148.576 1.00 58.61  ? 215 GLU A CG  1 
ATOM   842  C  CD  . GLU A 1 134 ? 121.056 95.060  148.618 1.00 58.61  ? 215 GLU A CD  1 
ATOM   843  O  OE1 . GLU A 1 134 ? 121.915 94.235  148.995 1.00 58.61  ? 215 GLU A OE1 1 
ATOM   844  O  OE2 . GLU A 1 134 ? 119.902 94.729  148.272 1.00 58.61  ? 215 GLU A OE2 1 
ATOM   845  N  N   . ILE A 1 135 ? 125.673 98.192  147.640 1.00 55.53  ? 216 ILE A N   1 
ATOM   846  C  CA  . ILE A 1 135 ? 126.989 98.773  147.885 1.00 55.53  ? 216 ILE A CA  1 
ATOM   847  C  C   . ILE A 1 135 ? 126.787 100.132 148.547 1.00 55.53  ? 216 ILE A C   1 
ATOM   848  O  O   . ILE A 1 135 ? 126.121 101.002 147.969 1.00 55.53  ? 216 ILE A O   1 
ATOM   849  C  CB  . ILE A 1 135 ? 127.802 98.907  146.589 1.00 55.53  ? 216 ILE A CB  1 
ATOM   850  C  CG1 . ILE A 1 135 ? 128.072 97.530  145.983 1.00 55.53  ? 216 ILE A CG1 1 
ATOM   851  C  CG2 . ILE A 1 135 ? 129.108 99.639  146.850 1.00 55.53  ? 216 ILE A CG2 1 
ATOM   852  C  CD1 . ILE A 1 135 ? 128.641 97.583  144.584 1.00 55.53  ? 216 ILE A CD1 1 
ATOM   853  N  N   . PRO A 1 136 ? 127.325 100.360 149.740 1.00 54.51  ? 217 PRO A N   1 
ATOM   854  C  CA  . PRO A 1 136 ? 127.199 101.668 150.382 1.00 54.51  ? 217 PRO A CA  1 
ATOM   855  C  C   . PRO A 1 136 ? 128.284 102.636 149.931 1.00 54.51  ? 217 PRO A C   1 
ATOM   856  O  O   . PRO A 1 136 ? 129.310 102.253 149.365 1.00 54.51  ? 217 PRO A O   1 
ATOM   857  C  CB  . PRO A 1 136 ? 127.351 101.333 151.871 1.00 54.51  ? 217 PRO A CB  1 
ATOM   858  C  CG  . PRO A 1 136 ? 128.274 100.157 151.880 1.00 54.51  ? 217 PRO A CG  1 
ATOM   859  C  CD  . PRO A 1 136 ? 128.039 99.392  150.593 1.00 54.51  ? 217 PRO A CD  1 
ATOM   860  N  N   . SER A 1 137 ? 128.032 103.914 150.196 1.00 52.58  ? 218 SER A N   1 
ATOM   861  C  CA  . SER A 1 137 ? 128.989 104.953 149.847 1.00 52.58  ? 218 SER A CA  1 
ATOM   862  C  C   . SER A 1 137 ? 130.168 104.941 150.812 1.00 52.58  ? 218 SER A C   1 
ATOM   863  O  O   . SER A 1 137 ? 130.104 104.366 151.902 1.00 52.58  ? 218 SER A O   1 
ATOM   864  C  CB  . SER A 1 137 ? 128.318 106.324 149.857 1.00 52.58  ? 218 SER A CB  1 
ATOM   865  O  OG  . SER A 1 137 ? 129.283 107.359 149.838 1.00 52.58  ? 218 SER A OG  1 
ATOM   866  N  N   . TRP A 1 138 ? 131.257 105.588 150.400 1.00 54.30  ? 219 TRP A N   1 
ATOM   867  C  CA  . TRP A 1 138 ? 132.475 105.632 151.195 1.00 54.30  ? 219 TRP A CA  1 
ATOM   868  C  C   . TRP A 1 138 ? 132.995 107.040 151.447 1.00 54.30  ? 219 TRP A C   1 
ATOM   869  O  O   . TRP A 1 138 ? 133.942 107.199 152.225 1.00 54.30  ? 219 TRP A O   1 
ATOM   870  C  CB  . TRP A 1 138 ? 133.571 104.787 150.528 1.00 54.30  ? 219 TRP A CB  1 
ATOM   871  C  CG  . TRP A 1 138 ? 133.893 105.196 149.124 1.00 54.30  ? 219 TRP A CG  1 
ATOM   872  C  CD1 . TRP A 1 138 ? 134.799 106.135 148.730 1.00 54.30  ? 219 TRP A CD1 1 
ATOM   873  C  CD2 . TRP A 1 138 ? 133.306 104.677 147.925 1.00 54.30  ? 219 TRP A CD2 1 
ATOM   874  N  NE1 . TRP A 1 138 ? 134.815 106.232 147.360 1.00 54.30  ? 219 TRP A NE1 1 
ATOM   875  C  CE2 . TRP A 1 138 ? 133.907 105.347 146.842 1.00 54.30  ? 219 TRP A CE2 1 
ATOM   876  C  CE3 . TRP A 1 138 ? 132.331 103.710 147.662 1.00 54.30  ? 219 TRP A CE3 1 
ATOM   877  C  CZ2 . TRP A 1 138 ? 133.565 105.083 145.519 1.00 54.30  ? 219 TRP A CZ2 1 
ATOM   878  C  CZ3 . TRP A 1 138 ? 131.994 103.449 146.349 1.00 54.30  ? 219 TRP A CZ3 1 
ATOM   879  C  CH2 . TRP A 1 138 ? 132.608 104.132 145.294 1.00 54.30  ? 219 TRP A CH2 1 
ATOM   880  N  N   . VAL A 1 139 ? 132.413 108.060 150.818 1.00 53.11  ? 220 VAL A N   1 
ATOM   881  C  CA  . VAL A 1 139 ? 132.747 109.447 151.123 1.00 53.11  ? 220 VAL A CA  1 
ATOM   882  C  C   . VAL A 1 139 ? 131.462 110.172 151.503 1.00 53.11  ? 220 VAL A C   1 
ATOM   883  O  O   . VAL A 1 139 ? 131.480 111.136 152.277 1.00 53.11  ? 220 VAL A O   1 
ATOM   884  C  CB  . VAL A 1 139 ? 133.456 110.128 149.937 1.00 53.11  ? 220 VAL A CB  1 
ATOM   885  C  CG1 . VAL A 1 139 ? 133.706 111.601 150.223 1.00 53.11  ? 220 VAL A CG1 1 
ATOM   886  C  CG2 . VAL A 1 139 ? 134.767 109.426 149.630 1.00 53.11  ? 220 VAL A CG2 1 
ATOM   887  N  N   . GLY A 1 140 ? 130.335 109.690 150.987 1.00 53.21  ? 221 GLY A N   1 
ATOM   888  C  CA  . GLY A 1 140 ? 129.049 110.263 151.329 1.00 53.21  ? 221 GLY A CA  1 
ATOM   889  C  C   . GLY A 1 140 ? 128.730 111.581 150.663 1.00 53.21  ? 221 GLY A C   1 
ATOM   890  O  O   . GLY A 1 140 ? 128.015 112.401 151.246 1.00 53.21  ? 221 GLY A O   1 
ATOM   891  N  N   . ASN A 1 141 ? 129.246 111.818 149.453 1.00 54.52  ? 222 ASN A N   1 
ATOM   892  C  CA  . ASN A 1 141 ? 128.971 113.044 148.701 1.00 54.52  ? 222 ASN A CA  1 
ATOM   893  C  C   . ASN A 1 141 ? 128.551 112.642 147.288 1.00 54.52  ? 222 ASN A C   1 
ATOM   894  O  O   . ASN A 1 141 ? 129.366 112.663 146.364 1.00 54.52  ? 222 ASN A O   1 
ATOM   895  C  CB  . ASN A 1 141 ? 130.200 113.963 148.699 1.00 54.52  ? 222 ASN A CB  1 
ATOM   896  C  CG  . ASN A 1 141 ? 129.947 115.290 148.007 1.00 54.52  ? 222 ASN A CG  1 
ATOM   897  O  OD1 . ASN A 1 141 ? 128.898 115.505 147.399 1.00 54.52  ? 222 ASN A OD1 1 
ATOM   898  N  ND2 . ASN A 1 141 ? 130.917 116.191 148.096 1.00 54.52  ? 222 ASN A ND2 1 
ATOM   899  N  N   . ILE A 1 142 ? 127.268 112.313 147.130 1.00 56.58  ? 223 ILE A N   1 
ATOM   900  C  CA  . ILE A 1 142 ? 126.663 111.982 145.841 1.00 56.58  ? 223 ILE A CA  1 
ATOM   901  C  C   . ILE A 1 142 ? 127.447 110.890 145.119 1.00 56.58  ? 223 ILE A C   1 
ATOM   902  O  O   . ILE A 1 142 ? 128.388 111.170 144.366 1.00 56.58  ? 223 ILE A O   1 
ATOM   903  C  CB  . ILE A 1 142 ? 126.517 113.240 144.964 1.00 56.58  ? 223 ILE A CB  1 
ATOM   904  C  CG1 . ILE A 1 142 ? 125.584 114.246 145.635 1.00 56.58  ? 223 ILE A CG1 1 
ATOM   905  C  CG2 . ILE A 1 142 ? 125.980 112.896 143.595 1.00 56.58  ? 223 ILE A CG2 1 
ATOM   906  C  CD1 . ILE A 1 142 ? 125.401 115.515 144.844 1.00 56.58  ? 223 ILE A CD1 1 
ATOM   907  N  N   . LEU A 1 143 ? 127.069 109.636 145.352 1.00 57.45  ? 224 LEU A N   1 
ATOM   908  C  CA  . LEU A 1 143 ? 127.657 108.524 144.617 1.00 57.45  ? 224 LEU A CA  1 
ATOM   909  C  C   . LEU A 1 143 ? 127.106 108.494 143.195 1.00 57.45  ? 224 LEU A C   1 
ATOM   910  O  O   . LEU A 1 143 ? 125.899 108.647 142.984 1.00 57.45  ? 224 LEU A O   1 
ATOM   911  C  CB  . LEU A 1 143 ? 127.366 107.208 145.335 1.00 57.45  ? 224 LEU A CB  1 
ATOM   912  C  CG  . LEU A 1 143 ? 127.892 105.924 144.697 1.00 57.45  ? 224 LEU A CG  1 
ATOM   913  C  CD1 . LEU A 1 143 ? 129.355 105.716 145.047 1.00 57.45  ? 224 LEU A CD1 1 
ATOM   914  C  CD2 . LEU A 1 143 ? 127.059 104.734 145.140 1.00 57.45  ? 224 LEU A CD2 1 
ATOM   915  N  N   . ARG A 1 144 ? 127.990 108.302 142.219 1.00 57.72  ? 225 ARG A N   1 
ATOM   916  C  CA  . ARG A 1 144 ? 127.607 108.344 140.815 1.00 57.72  ? 225 ARG A CA  1 
ATOM   917  C  C   . ARG A 1 144 ? 128.287 107.213 140.055 1.00 57.72  ? 225 ARG A C   1 
ATOM   918  O  O   . ARG A 1 144 ? 129.327 106.694 140.469 1.00 57.72  ? 225 ARG A O   1 
ATOM   919  C  CB  . ARG A 1 144 ? 127.954 109.697 140.184 1.00 57.72  ? 225 ARG A CB  1 
ATOM   920  C  CG  . ARG A 1 144 ? 129.186 110.354 140.776 1.00 57.72  ? 225 ARG A CG  1 
ATOM   921  C  CD  . ARG A 1 144 ? 129.277 111.813 140.370 1.00 57.72  ? 225 ARG A CD  1 
ATOM   922  N  NE  . ARG A 1 144 ? 130.481 112.449 140.888 1.00 57.72  ? 225 ARG A NE  1 
ATOM   923  C  CZ  . ARG A 1 144 ? 130.531 113.160 142.005 1.00 57.72  ? 225 ARG A CZ  1 
ATOM   924  N  NH1 . ARG A 1 144 ? 129.457 113.345 142.755 1.00 57.72  ? 225 ARG A NH1 1 
ATOM   925  N  NH2 . ARG A 1 144 ? 131.687 113.700 142.381 1.00 57.72  ? 225 ARG A NH2 1 
ATOM   926  N  N   . THR A 1 145 ? 127.682 106.838 138.932 1.00 58.84  ? 226 THR A N   1 
ATOM   927  C  CA  . THR A 1 145 ? 128.186 105.795 138.048 1.00 58.84  ? 226 THR A CA  1 
ATOM   928  C  C   . THR A 1 145 ? 128.506 106.389 136.676 1.00 58.84  ? 226 THR A C   1 
ATOM   929  O  O   . THR A 1 145 ? 128.484 107.607 136.477 1.00 58.84  ? 226 THR A O   1 
ATOM   930  C  CB  . THR A 1 145 ? 127.188 104.640 137.927 1.00 58.84  ? 226 THR A CB  1 
ATOM   931  O  OG1 . THR A 1 145 ? 125.901 105.149 137.557 1.00 58.84  ? 226 THR A OG1 1 
ATOM   932  C  CG2 . THR A 1 145 ? 127.088 103.872 139.231 1.00 58.84  ? 226 THR A CG2 1 
ATOM   933  N  N   . GLN A 1 146 ? 128.808 105.504 135.724 1.00 61.09  ? 227 GLN A N   1 
ATOM   934  C  CA  . GLN A 1 146 ? 129.271 105.944 134.412 1.00 61.09  ? 227 GLN A CA  1 
ATOM   935  C  C   . GLN A 1 146 ? 128.144 106.514 133.558 1.00 61.09  ? 227 GLN A C   1 
ATOM   936  O  O   . GLN A 1 146 ? 128.414 107.232 132.588 1.00 61.09  ? 227 GLN A O   1 
ATOM   937  C  CB  . GLN A 1 146 ? 129.951 104.785 133.687 1.00 61.09  ? 227 GLN A CB  1 
ATOM   938  C  CG  . GLN A 1 146 ? 130.999 104.057 134.506 1.00 61.09  ? 227 GLN A CG  1 
ATOM   939  C  CD  . GLN A 1 146 ? 131.288 102.669 133.972 1.00 61.09  ? 227 GLN A CD  1 
ATOM   940  O  OE1 . GLN A 1 146 ? 131.852 101.829 134.671 1.00 61.09  ? 227 GLN A OE1 1 
ATOM   941  N  NE2 . GLN A 1 146 ? 130.902 102.422 132.726 1.00 61.09  ? 227 GLN A NE2 1 
ATOM   942  N  N   . GLU A 1 147 ? 126.890 106.201 133.887 1.00 63.21  ? 228 GLU A N   1 
ATOM   943  C  CA  . GLU A 1 147 ? 125.727 106.696 133.145 1.00 63.21  ? 228 GLU A CA  1 
ATOM   944  C  C   . GLU A 1 147 ? 125.828 106.345 131.659 1.00 63.21  ? 228 GLU A C   1 
ATOM   945  O  O   . GLU A 1 147 ? 125.462 107.128 130.780 1.00 63.21  ? 228 GLU A O   1 
ATOM   946  C  CB  . GLU A 1 147 ? 125.548 108.204 133.347 1.00 63.21  ? 228 GLU A CB  1 
ATOM   947  C  CG  . GLU A 1 147 ? 124.125 108.708 133.135 1.00 63.21  ? 228 GLU A CG  1 
ATOM   948  C  CD  . GLU A 1 147 ? 123.082 107.824 133.794 1.00 63.21  ? 228 GLU A CD  1 
ATOM   949  O  OE1 . GLU A 1 147 ? 123.221 107.533 135.001 1.00 63.21  ? 228 GLU A OE1 1 
ATOM   950  O  OE2 . GLU A 1 147 ? 122.123 107.421 133.103 1.00 63.21  ? 228 GLU A OE2 1 
ATOM   951  N  N   . SER A 1 148 ? 126.339 105.150 131.385 1.00 64.82  ? 229 SER A N   1 
ATOM   952  C  CA  . SER A 1 148 ? 126.447 104.630 130.028 1.00 64.82  ? 229 SER A CA  1 
ATOM   953  C  C   . SER A 1 148 ? 126.338 103.113 130.101 1.00 64.82  ? 229 SER A C   1 
ATOM   954  O  O   . SER A 1 148 ? 125.916 102.554 131.118 1.00 64.82  ? 229 SER A O   1 
ATOM   955  C  CB  . SER A 1 148 ? 127.754 105.085 129.367 1.00 64.82  ? 229 SER A CB  1 
ATOM   956  O  OG  . SER A 1 148 ? 128.879 104.561 130.049 1.00 64.82  ? 229 SER A OG  1 
ATOM   957  N  N   . GLU A 1 149 ? 126.721 102.439 129.022 1.00 65.81  ? 230 GLU A N   1 
ATOM   958  C  CA  . GLU A 1 149 ? 126.724 100.989 129.067 1.00 65.81  ? 230 GLU A CA  1 
ATOM   959  C  C   . GLU A 1 149 ? 128.016 100.487 129.702 1.00 65.81  ? 230 GLU A C   1 
ATOM   960  O  O   . GLU A 1 149 ? 129.032 101.186 129.756 1.00 65.81  ? 230 GLU A O   1 
ATOM   961  C  CB  . GLU A 1 149 ? 126.584 100.382 127.672 1.00 65.81  ? 230 GLU A CB  1 
ATOM   962  C  CG  . GLU A 1 149 ? 127.835 100.504 126.821 1.00 65.81  ? 230 GLU A CG  1 
ATOM   963  C  CD  . GLU A 1 149 ? 127.684 99.850  125.464 1.00 65.81  ? 230 GLU A CD  1 
ATOM   964  O  OE1 . GLU A 1 149 ? 126.577 99.361  125.155 1.00 65.81  ? 230 GLU A OE1 1 
ATOM   965  O  OE2 . GLU A 1 149 ? 128.685 99.796  124.720 1.00 65.81  ? 230 GLU A OE2 1 
ATOM   966  N  N   . CYS A 1 150 ? 127.962 99.256  130.188 1.00 63.24  ? 231 CYS A N   1 
ATOM   967  C  CA  . CYS A 1 150 ? 129.120 98.538  130.696 1.00 63.24  ? 231 CYS A CA  1 
ATOM   968  C  C   . CYS A 1 150 ? 129.480 97.400  129.742 1.00 63.24  ? 231 CYS A C   1 
ATOM   969  O  O   . CYS A 1 150 ? 128.797 97.153  128.745 1.00 63.24  ? 231 CYS A O   1 
ATOM   970  C  CB  . CYS A 1 150 ? 128.867 98.080  132.139 1.00 63.24  ? 231 CYS A CB  1 
ATOM   971  S  SG  . CYS A 1 150 ? 127.380 97.080  132.509 1.00 63.24  ? 231 CYS A SG  1 
ATOM   972  N  N   . VAL A 1 151 ? 130.597 96.735  130.026 1.00 61.30  ? 232 VAL A N   1 
ATOM   973  C  CA  . VAL A 1 151 ? 131.128 95.683  129.169 1.00 61.30  ? 232 VAL A CA  1 
ATOM   974  C  C   . VAL A 1 151 ? 131.316 94.429  130.008 1.00 61.30  ? 232 VAL A C   1 
ATOM   975  O  O   . VAL A 1 151 ? 131.849 94.497  131.121 1.00 61.30  ? 232 VAL A O   1 
ATOM   976  C  CB  . VAL A 1 151 ? 132.458 96.094  128.508 1.00 61.30  ? 232 VAL A CB  1 
ATOM   977  C  CG1 . VAL A 1 151 ? 132.824 95.114  127.404 1.00 61.30  ? 232 VAL A CG1 1 
ATOM   978  C  CG2 . VAL A 1 151 ? 132.369 97.507  127.959 1.00 61.30  ? 232 VAL A CG2 1 
ATOM   979  N  N   . CYS A 1 152 ? 130.880 93.291  129.479 1.00 61.72  ? 233 CYS A N   1 
ATOM   980  C  CA  . CYS A 1 152 ? 130.966 92.015  130.173 1.00 61.72  ? 233 CYS A CA  1 
ATOM   981  C  C   . CYS A 1 152 ? 131.821 91.049  129.365 1.00 61.72  ? 233 CYS A C   1 
ATOM   982  O  O   . CYS A 1 152 ? 131.591 90.861  128.166 1.00 61.72  ? 233 CYS A O   1 
ATOM   983  C  CB  . CYS A 1 152 ? 129.575 91.424  130.405 1.00 61.72  ? 233 CYS A CB  1 
ATOM   984  S  SG  . CYS A 1 152 ? 128.586 92.293  131.644 1.00 61.72  ? 233 CYS A SG  1 
ATOM   985  N  N   . HIS A 1 153 ? 132.803 90.441  130.027 1.00 59.08  ? 234 HIS A N   1 
ATOM   986  C  CA  . HIS A 1 153 ? 133.725 89.496  129.407 1.00 59.08  ? 234 HIS A CA  1 
ATOM   987  C  C   . HIS A 1 153 ? 133.797 88.264  130.299 1.00 59.08  ? 234 HIS A C   1 
ATOM   988  O  O   . HIS A 1 153 ? 134.303 88.338  131.424 1.00 59.08  ? 234 HIS A O   1 
ATOM   989  C  CB  . HIS A 1 153 ? 135.107 90.121  129.217 1.00 59.08  ? 234 HIS A CB  1 
ATOM   990  C  CG  . HIS A 1 153 ? 136.127 89.181  128.655 1.00 59.08  ? 234 HIS A CG  1 
ATOM   991  N  ND1 . HIS A 1 153 ? 137.471 89.478  128.625 1.00 59.08  ? 234 HIS A ND1 1 
ATOM   992  C  CD2 . HIS A 1 153 ? 135.999 87.958  128.089 1.00 59.08  ? 234 HIS A CD2 1 
ATOM   993  C  CE1 . HIS A 1 153 ? 138.129 88.475  128.071 1.00 59.08  ? 234 HIS A CE1 1 
ATOM   994  N  NE2 . HIS A 1 153 ? 137.259 87.539  127.738 1.00 59.08  ? 234 HIS A NE2 1 
ATOM   995  N  N   . LYS A 1 154 ? 133.284 87.140  129.798 1.00 58.84  ? 235 LYS A N   1 
ATOM   996  C  CA  . LYS A 1 154 ? 133.244 85.872  130.523 1.00 58.84  ? 235 LYS A CA  1 
ATOM   997  C  C   . LYS A 1 154 ? 132.630 86.018  131.910 1.00 58.84  ? 235 LYS A C   1 
ATOM   998  O  O   . LYS A 1 154 ? 133.070 85.363  132.860 1.00 58.84  ? 235 LYS A O   1 
ATOM   999  C  CB  . LYS A 1 154 ? 134.638 85.244  130.627 1.00 58.84  ? 235 LYS A CB  1 
ATOM   1000 C  CG  . LYS A 1 154 ? 135.171 84.703  129.312 1.00 58.84  ? 235 LYS A CG  1 
ATOM   1001 C  CD  . LYS A 1 154 ? 136.686 84.589  129.332 1.00 58.84  ? 235 LYS A CD  1 
ATOM   1002 C  CE  . LYS A 1 154 ? 137.181 83.644  128.250 1.00 58.84  ? 235 LYS A CE  1 
ATOM   1003 N  NZ  . LYS A 1 154 ? 136.461 82.341  128.279 1.00 58.84  ? 235 LYS A NZ  1 
ATOM   1004 N  N   . GLY A 1 155 ? 131.618 86.870  132.041 1.00 59.37  ? 236 GLY A N   1 
ATOM   1005 C  CA  . GLY A 1 155 ? 130.947 87.102  133.303 1.00 59.37  ? 236 GLY A CA  1 
ATOM   1006 C  C   . GLY A 1 155 ? 131.470 88.281  134.092 1.00 59.37  ? 236 GLY A C   1 
ATOM   1007 O  O   . GLY A 1 155 ? 130.753 88.778  134.969 1.00 59.37  ? 236 GLY A O   1 
ATOM   1008 N  N   . ILE A 1 156 ? 132.680 88.757  133.810 1.00 57.35  ? 237 ILE A N   1 
ATOM   1009 C  CA  . ILE A 1 156 ? 133.277 89.868  134.542 1.00 57.35  ? 237 ILE A CA  1 
ATOM   1010 C  C   . ILE A 1 156 ? 132.811 91.165  133.898 1.00 57.35  ? 237 ILE A C   1 
ATOM   1011 O  O   . ILE A 1 156 ? 133.075 91.409  132.716 1.00 57.35  ? 237 ILE A O   1 
ATOM   1012 C  CB  . ILE A 1 156 ? 134.811 89.773  134.555 1.00 57.35  ? 237 ILE A CB  1 
ATOM   1013 C  CG1 . ILE A 1 156 ? 135.256 88.461  135.202 1.00 57.35  ? 237 ILE A CG1 1 
ATOM   1014 C  CG2 . ILE A 1 156 ? 135.412 90.959  135.291 1.00 57.35  ? 237 ILE A CG2 1 
ATOM   1015 C  CD1 . ILE A 1 156 ? 134.818 88.309  136.642 1.00 57.35  ? 237 ILE A CD1 1 
ATOM   1016 N  N   . CYS A 1 157 ? 132.115 91.995  134.669 1.00 59.74  ? 238 CYS A N   1 
ATOM   1017 C  CA  . CYS A 1 157 ? 131.532 93.237  134.158 1.00 59.74  ? 238 CYS A CA  1 
ATOM   1018 C  C   . CYS A 1 157 ? 132.025 94.422  134.977 1.00 59.74  ? 238 CYS A C   1 
ATOM   1019 O  O   . CYS A 1 157 ? 131.415 94.767  136.005 1.00 59.74  ? 238 CYS A O   1 
ATOM   1020 C  CB  . CYS A 1 157 ? 130.007 93.162  134.185 1.00 59.74  ? 238 CYS A CB  1 
ATOM   1021 S  SG  . CYS A 1 157 ? 129.331 91.666  133.426 1.00 59.74  ? 238 CYS A SG  1 
ATOM   1022 N  N   . PRO A 1 158 ? 133.120 95.069  134.576 1.00 56.58  ? 239 PRO A N   1 
ATOM   1023 C  CA  . PRO A 1 158 ? 133.630 96.207  135.351 1.00 56.58  ? 239 PRO A CA  1 
ATOM   1024 C  C   . PRO A 1 158 ? 132.659 97.379  135.353 1.00 56.58  ? 239 PRO A C   1 
ATOM   1025 O  O   . PRO A 1 158 ? 131.969 97.644  134.366 1.00 56.58  ? 239 PRO A O   1 
ATOM   1026 C  CB  . PRO A 1 158 ? 134.937 96.565  134.634 1.00 56.58  ? 239 PRO A CB  1 
ATOM   1027 C  CG  . PRO A 1 158 ? 135.309 95.339  133.869 1.00 56.58  ? 239 PRO A CG  1 
ATOM   1028 C  CD  . PRO A 1 158 ? 134.017 94.706  133.469 1.00 56.58  ? 239 PRO A CD  1 
ATOM   1029 N  N   . VAL A 1 159 ? 132.616 98.084  136.483 1.00 56.62  ? 240 VAL A N   1 
ATOM   1030 C  CA  . VAL A 1 159 ? 131.829 99.303  136.638 1.00 56.62  ? 240 VAL A CA  1 
ATOM   1031 C  C   . VAL A 1 159 ? 132.671 100.309 137.410 1.00 56.62  ? 240 VAL A C   1 
ATOM   1032 O  O   . VAL A 1 159 ? 133.226 99.981  138.463 1.00 56.62  ? 240 VAL A O   1 
ATOM   1033 C  CB  . VAL A 1 159 ? 130.494 99.038  137.361 1.00 56.62  ? 240 VAL A CB  1 
ATOM   1034 C  CG1 . VAL A 1 159 ? 129.930 100.327 137.940 1.00 56.62  ? 240 VAL A CG1 1 
ATOM   1035 C  CG2 . VAL A 1 159 ? 129.494 98.396  136.415 1.00 56.62  ? 240 VAL A CG2 1 
ATOM   1036 N  N   . VAL A 1 160 ? 132.768 101.529 136.895 1.00 56.01  ? 241 VAL A N   1 
ATOM   1037 C  CA  . VAL A 1 160 ? 133.559 102.586 137.514 1.00 56.01  ? 241 VAL A CA  1 
ATOM   1038 C  C   . VAL A 1 160 ? 132.617 103.500 138.285 1.00 56.01  ? 241 VAL A C   1 
ATOM   1039 O  O   . VAL A 1 160 ? 131.665 104.045 137.713 1.00 56.01  ? 241 VAL A O   1 
ATOM   1040 C  CB  . VAL A 1 160 ? 134.359 103.374 136.466 1.00 56.01  ? 241 VAL A CB  1 
ATOM   1041 C  CG1 . VAL A 1 160 ? 135.094 104.530 137.119 1.00 56.01  ? 241 VAL A CG1 1 
ATOM   1042 C  CG2 . VAL A 1 160 ? 135.332 102.457 135.746 1.00 56.01  ? 241 VAL A CG2 1 
ATOM   1043 N  N   . MET A 1 161 ? 132.873 103.671 139.581 1.00 58.34  ? 242 MET A N   1 
ATOM   1044 C  CA  . MET A 1 161 ? 132.088 104.566 140.416 1.00 58.34  ? 242 MET A CA  1 
ATOM   1045 C  C   . MET A 1 161 ? 132.992 105.619 141.038 1.00 58.34  ? 242 MET A C   1 
ATOM   1046 O  O   . MET A 1 161 ? 134.196 105.406 141.210 1.00 58.34  ? 242 MET A O   1 
ATOM   1047 C  CB  . MET A 1 161 ? 131.341 103.805 141.517 1.00 58.34  ? 242 MET A CB  1 
ATOM   1048 C  CG  . MET A 1 161 ? 130.246 102.889 141.002 1.00 58.34  ? 242 MET A CG  1 
ATOM   1049 S  SD  . MET A 1 161 ? 129.396 102.007 142.323 1.00 58.34  ? 242 MET A SD  1 
ATOM   1050 C  CE  . MET A 1 161 ? 128.276 100.980 141.378 1.00 58.34  ? 242 MET A CE  1 
ATOM   1051 N  N   . THR A 1 162 ? 132.403 106.767 141.363 1.00 57.00  ? 243 THR A N   1 
ATOM   1052 C  CA  . THR A 1 162 ? 133.139 107.882 141.938 1.00 57.00  ? 243 THR A CA  1 
ATOM   1053 C  C   . THR A 1 162 ? 132.321 108.494 143.064 1.00 57.00  ? 243 THR A C   1 
ATOM   1054 O  O   . THR A 1 162 ? 131.088 108.515 143.005 1.00 57.00  ? 243 THR A O   1 
ATOM   1055 C  CB  . THR A 1 162 ? 133.458 108.947 140.880 1.00 57.00  ? 243 THR A CB  1 
ATOM   1056 O  OG1 . THR A 1 162 ? 133.930 108.310 139.687 1.00 57.00  ? 243 THR A OG1 1 
ATOM   1057 C  CG2 . THR A 1 162 ? 134.523 109.908 141.384 1.00 57.00  ? 243 THR A CG2 1 
ATOM   1058 N  N   . ASP A 1 163 ? 133.012 108.987 144.090 1.00 56.44  ? 244 ASP A N   1 
ATOM   1059 C  CA  . ASP A 1 163 ? 132.354 109.640 145.212 1.00 56.44  ? 244 ASP A CA  1 
ATOM   1060 C  C   . ASP A 1 163 ? 133.236 110.779 145.701 1.00 56.44  ? 244 ASP A C   1 
ATOM   1061 O  O   . ASP A 1 163 ? 134.456 110.628 145.809 1.00 56.44  ? 244 ASP A O   1 
ATOM   1062 C  CB  . ASP A 1 163 ? 132.077 108.649 146.348 1.00 56.44  ? 244 ASP A CB  1 
ATOM   1063 C  CG  . ASP A 1 163 ? 131.183 109.229 147.427 1.00 56.44  ? 244 ASP A CG  1 
ATOM   1064 O  OD1 . ASP A 1 163 ? 130.796 110.411 147.319 1.00 56.44  ? 244 ASP A OD1 1 
ATOM   1065 O  OD2 . ASP A 1 163 ? 130.865 108.500 148.390 1.00 56.44  ? 244 ASP A OD2 1 
ATOM   1066 N  N   . GLY A 1 164 ? 132.612 111.913 145.999 1.00 56.17  ? 245 GLY A N   1 
ATOM   1067 C  CA  . GLY A 1 164 ? 133.331 113.063 146.491 1.00 56.17  ? 245 GLY A CA  1 
ATOM   1068 C  C   . GLY A 1 164 ? 133.015 114.323 145.714 1.00 56.17  ? 245 GLY A C   1 
ATOM   1069 O  O   . GLY A 1 164 ? 132.013 114.407 144.997 1.00 56.17  ? 245 GLY A O   1 
ATOM   1070 N  N   . PRO A 1 165 ? 133.866 115.338 145.856 1.00 54.62  ? 246 PRO A N   1 
ATOM   1071 C  CA  . PRO A 1 165 ? 133.642 116.595 145.133 1.00 54.62  ? 246 PRO A CA  1 
ATOM   1072 C  C   . PRO A 1 165 ? 133.683 116.389 143.627 1.00 54.62  ? 246 PRO A C   1 
ATOM   1073 O  O   . PRO A 1 165 ? 134.447 115.571 143.112 1.00 54.62  ? 246 PRO A O   1 
ATOM   1074 C  CB  . PRO A 1 165 ? 134.794 117.489 145.607 1.00 54.62  ? 246 PRO A CB  1 
ATOM   1075 C  CG  . PRO A 1 165 ? 135.254 116.883 146.891 1.00 54.62  ? 246 PRO A CG  1 
ATOM   1076 C  CD  . PRO A 1 165 ? 135.028 115.412 146.756 1.00 54.62  ? 246 PRO A CD  1 
ATOM   1077 N  N   . ALA A 1 166 ? 132.845 117.144 142.921 1.00 54.14  ? 247 ALA A N   1 
ATOM   1078 C  CA  . ALA A 1 166 ? 132.823 117.124 141.465 1.00 54.14  ? 247 ALA A CA  1 
ATOM   1079 C  C   . ALA A 1 166 ? 133.720 118.189 140.851 1.00 54.14  ? 247 ALA A C   1 
ATOM   1080 O  O   . ALA A 1 166 ? 133.826 118.256 139.622 1.00 54.14  ? 247 ALA A O   1 
ATOM   1081 C  CB  . ALA A 1 166 ? 131.391 117.298 140.955 1.00 54.14  ? 247 ALA A CB  1 
ATOM   1082 N  N   . ASN A 1 167 ? 134.367 119.019 141.673 1.00 53.95  ? 248 ASN A N   1 
ATOM   1083 C  CA  . ASN A 1 167 ? 135.297 120.029 141.185 1.00 53.95  ? 248 ASN A CA  1 
ATOM   1084 C  C   . ASN A 1 167 ? 136.603 119.993 141.969 1.00 53.95  ? 248 ASN A C   1 
ATOM   1085 O  O   . ASN A 1 167 ? 137.260 121.026 142.136 1.00 53.95  ? 248 ASN A O   1 
ATOM   1086 C  CB  . ASN A 1 167 ? 134.682 121.427 141.253 1.00 53.95  ? 248 ASN A CB  1 
ATOM   1087 C  CG  . ASN A 1 167 ? 133.382 121.529 140.482 1.00 53.95  ? 248 ASN A CG  1 
ATOM   1088 O  OD1 . ASN A 1 167 ? 133.376 121.546 139.251 1.00 53.95  ? 248 ASN A OD1 1 
ATOM   1089 N  ND2 . ASN A 1 167 ? 132.269 121.599 141.203 1.00 53.95  ? 248 ASN A ND2 1 
ATOM   1090 N  N   . ASN A 1 168 ? 136.983 118.819 142.459 1.00 58.21  ? 249 ASN A N   1 
ATOM   1091 C  CA  . ASN A 1 168 ? 138.203 118.635 143.235 1.00 58.21  ? 249 ASN A CA  1 
ATOM   1092 C  C   . ASN A 1 168 ? 138.542 117.148 143.227 1.00 58.21  ? 249 ASN A C   1 
ATOM   1093 O  O   . ASN A 1 168 ? 137.961 116.367 142.465 1.00 58.21  ? 249 ASN A O   1 
ATOM   1094 C  CB  . ASN A 1 168 ? 138.037 119.182 144.657 1.00 58.21  ? 249 ASN A CB  1 
ATOM   1095 C  CG  . ASN A 1 168 ? 139.289 119.866 145.167 1.00 58.21  ? 249 ASN A CG  1 
ATOM   1096 O  OD1 . ASN A 1 168 ? 140.400 119.548 144.744 1.00 58.21  ? 249 ASN A OD1 1 
ATOM   1097 N  ND2 . ASN A 1 168 ? 139.115 120.811 146.082 1.00 58.21  ? 249 ASN A ND2 1 
ATOM   1098 N  N   . LYS A 1 169 ? 139.492 116.755 144.072 1.00 56.27  ? 250 LYS A N   1 
ATOM   1099 C  CA  . LYS A 1 169 ? 139.866 115.351 144.174 1.00 56.27  ? 250 LYS A CA  1 
ATOM   1100 C  C   . LYS A 1 169 ? 138.705 114.527 144.718 1.00 56.27  ? 250 LYS A C   1 
ATOM   1101 O  O   . LYS A 1 169 ? 138.070 114.902 145.707 1.00 56.27  ? 250 LYS A O   1 
ATOM   1102 C  CB  . LYS A 1 169 ? 141.092 115.197 145.072 1.00 56.27  ? 250 LYS A CB  1 
ATOM   1103 C  CG  . LYS A 1 169 ? 141.648 113.784 145.129 1.00 56.27  ? 250 LYS A CG  1 
ATOM   1104 C  CD  . LYS A 1 169 ? 142.867 113.707 146.033 1.00 56.27  ? 250 LYS A CD  1 
ATOM   1105 C  CE  . LYS A 1 169 ? 144.065 114.399 145.404 1.00 56.27  ? 250 LYS A CE  1 
ATOM   1106 N  NZ  . LYS A 1 169 ? 144.545 113.684 144.190 1.00 56.27  ? 250 LYS A NZ  1 
ATOM   1107 N  N   . ALA A 1 170 ? 138.433 113.398 144.067 1.00 55.53  ? 251 ALA A N   1 
ATOM   1108 C  CA  . ALA A 1 170 ? 137.369 112.492 144.469 1.00 55.53  ? 251 ALA A CA  1 
ATOM   1109 C  C   . ALA A 1 170 ? 137.874 111.059 144.401 1.00 55.53  ? 251 ALA A C   1 
ATOM   1110 O  O   . ALA A 1 170 ? 138.801 110.748 143.649 1.00 55.53  ? 251 ALA A O   1 
ATOM   1111 C  CB  . ALA A 1 170 ? 136.124 112.651 143.587 1.00 55.53  ? 251 ALA A CB  1 
ATOM   1112 N  N   . ALA A 1 171 ? 137.256 110.186 145.193 1.00 54.72  ? 252 ALA A N   1 
ATOM   1113 C  CA  . ALA A 1 171 ? 137.679 108.793 145.271 1.00 54.72  ? 252 ALA A CA  1 
ATOM   1114 C  C   . ALA A 1 171 ? 136.961 107.998 144.188 1.00 54.72  ? 252 ALA A C   1 
ATOM   1115 O  O   . ALA A 1 171 ? 135.726 107.935 144.167 1.00 54.72  ? 252 ALA A O   1 
ATOM   1116 C  CB  . ALA A 1 171 ? 137.390 108.224 146.656 1.00 54.72  ? 252 ALA A CB  1 
ATOM   1117 N  N   . THR A 1 172 ? 137.732 107.395 143.288 1.00 55.47  ? 253 THR A N   1 
ATOM   1118 C  CA  . THR A 1 172 ? 137.200 106.598 142.191 1.00 55.47  ? 253 THR A CA  1 
ATOM   1119 C  C   . THR A 1 172 ? 137.588 105.140 142.394 1.00 55.47  ? 253 THR A C   1 
ATOM   1120 O  O   . THR A 1 172 ? 138.766 104.828 142.592 1.00 55.47  ? 253 THR A O   1 
ATOM   1121 C  CB  . THR A 1 172 ? 137.721 107.097 140.842 1.00 55.47  ? 253 THR A CB  1 
ATOM   1122 O  OG1 . THR A 1 172 ? 137.448 108.498 140.712 1.00 55.47  ? 253 THR A OG1 1 
ATOM   1123 C  CG2 . THR A 1 172 ? 137.044 106.350 139.705 1.00 55.47  ? 253 THR A CG2 1 
ATOM   1124 N  N   . LYS A 1 173 ? 136.596 104.257 142.344 1.00 55.07  ? 254 LYS A N   1 
ATOM   1125 C  CA  . LYS A 1 173 ? 136.800 102.831 142.532 1.00 55.07  ? 254 LYS A CA  1 
ATOM   1126 C  C   . LYS A 1 173 ? 136.260 102.083 141.323 1.00 55.07  ? 254 LYS A C   1 
ATOM   1127 O  O   . LYS A 1 173 ? 135.398 102.580 140.589 1.00 55.07  ? 254 LYS A O   1 
ATOM   1128 C  CB  . LYS A 1 173 ? 136.116 102.329 143.811 1.00 55.07  ? 254 LYS A CB  1 
ATOM   1129 C  CG  . LYS A 1 173 ? 136.852 102.685 145.092 1.00 55.07  ? 254 LYS A CG  1 
ATOM   1130 C  CD  . LYS A 1 173 ? 136.117 102.161 146.315 1.00 55.07  ? 254 LYS A CD  1 
ATOM   1131 C  CE  . LYS A 1 173 ? 136.693 102.739 147.597 1.00 55.07  ? 254 LYS A CE  1 
ATOM   1132 N  NZ  . LYS A 1 173 ? 138.127 102.384 147.773 1.00 55.07  ? 254 LYS A NZ  1 
ATOM   1133 N  N   . ILE A 1 174 ? 136.789 100.881 141.106 1.00 53.23  ? 255 ILE A N   1 
ATOM   1134 C  CA  . ILE A 1 174 ? 136.323 100.002 140.042 1.00 53.23  ? 255 ILE A CA  1 
ATOM   1135 C  C   . ILE A 1 174 ? 135.856 98.702  140.676 1.00 53.23  ? 255 ILE A C   1 
ATOM   1136 O  O   . ILE A 1 174 ? 136.588 98.085  141.463 1.00 53.23  ? 255 ILE A O   1 
ATOM   1137 C  CB  . ILE A 1 174 ? 137.406 99.756  138.982 1.00 53.23  ? 255 ILE A CB  1 
ATOM   1138 C  CG1 . ILE A 1 174 ? 137.720 101.064 138.260 1.00 53.23  ? 255 ILE A CG1 1 
ATOM   1139 C  CG2 . ILE A 1 174 ? 136.952 98.701  137.988 1.00 53.23  ? 255 ILE A CG2 1 
ATOM   1140 C  CD1 . ILE A 1 174 ? 138.845 100.966 137.285 1.00 53.23  ? 255 ILE A CD1 1 
ATOM   1141 N  N   . ILE A 1 175 ? 134.639 98.293  140.330 1.00 55.09  ? 256 ILE A N   1 
ATOM   1142 C  CA  . ILE A 1 175 ? 133.939 97.177  140.951 1.00 55.09  ? 256 ILE A CA  1 
ATOM   1143 C  C   . ILE A 1 175 ? 133.651 96.152  139.863 1.00 55.09  ? 256 ILE A C   1 
ATOM   1144 O  O   . ILE A 1 175 ? 133.041 96.484  138.839 1.00 55.09  ? 256 ILE A O   1 
ATOM   1145 C  CB  . ILE A 1 175 ? 132.644 97.652  141.627 1.00 55.09  ? 256 ILE A CB  1 
ATOM   1146 C  CG1 . ILE A 1 175 ? 132.890 98.957  142.388 1.00 55.09  ? 256 ILE A CG1 1 
ATOM   1147 C  CG2 . ILE A 1 175 ? 132.087 96.600  142.548 1.00 55.09  ? 256 ILE A CG2 1 
ATOM   1148 C  CD1 . ILE A 1 175 ? 131.701 99.431  143.189 1.00 55.09  ? 256 ILE A CD1 1 
ATOM   1149 N  N   . TYR A 1 176 ? 134.081 94.911  140.075 1.00 55.33  ? 257 TYR A N   1 
ATOM   1150 C  CA  . TYR A 1 176 ? 133.919 93.861  139.079 1.00 55.33  ? 257 TYR A CA  1 
ATOM   1151 C  C   . TYR A 1 176 ? 132.819 92.904  139.516 1.00 55.33  ? 257 TYR A C   1 
ATOM   1152 O  O   . TYR A 1 176 ? 132.888 92.327  140.606 1.00 55.33  ? 257 TYR A O   1 
ATOM   1153 C  CB  . TYR A 1 176 ? 135.228 93.100  138.861 1.00 55.33  ? 257 TYR A CB  1 
ATOM   1154 C  CG  . TYR A 1 176 ? 136.402 93.972  138.463 1.00 55.33  ? 257 TYR A CG  1 
ATOM   1155 C  CD1 . TYR A 1 176 ? 137.084 94.728  139.405 1.00 55.33  ? 257 TYR A CD1 1 
ATOM   1156 C  CD2 . TYR A 1 176 ? 136.819 94.045  137.142 1.00 55.33  ? 257 TYR A CD2 1 
ATOM   1157 C  CE1 . TYR A 1 176 ? 138.153 95.523  139.046 1.00 55.33  ? 257 TYR A CE1 1 
ATOM   1158 C  CE2 . TYR A 1 176 ? 137.888 94.837  136.774 1.00 55.33  ? 257 TYR A CE2 1 
ATOM   1159 C  CZ  . TYR A 1 176 ? 138.551 95.574  137.729 1.00 55.33  ? 257 TYR A CZ  1 
ATOM   1160 O  OH  . TYR A 1 176 ? 139.614 96.367  137.368 1.00 55.33  ? 257 TYR A OH  1 
ATOM   1161 N  N   . PHE A 1 177 ? 131.812 92.738  138.664 1.00 58.12  ? 258 PHE A N   1 
ATOM   1162 C  CA  . PHE A 1 177 ? 130.647 91.925  138.973 1.00 58.12  ? 258 PHE A CA  1 
ATOM   1163 C  C   . PHE A 1 177 ? 130.665 90.643  138.152 1.00 58.12  ? 258 PHE A C   1 
ATOM   1164 O  O   . PHE A 1 177 ? 131.203 90.597  137.043 1.00 58.12  ? 258 PHE A O   1 
ATOM   1165 C  CB  . PHE A 1 177 ? 129.343 92.685  138.696 1.00 58.12  ? 258 PHE A CB  1 
ATOM   1166 C  CG  . PHE A 1 177 ? 129.061 93.785  139.674 1.00 58.12  ? 258 PHE A CG  1 
ATOM   1167 C  CD1 . PHE A 1 177 ? 129.668 95.021  139.539 1.00 58.12  ? 258 PHE A CD1 1 
ATOM   1168 C  CD2 . PHE A 1 177 ? 128.188 93.584  140.729 1.00 58.12  ? 258 PHE A CD2 1 
ATOM   1169 C  CE1 . PHE A 1 177 ? 129.409 96.036  140.434 1.00 58.12  ? 258 PHE A CE1 1 
ATOM   1170 C  CE2 . PHE A 1 177 ? 127.927 94.595  141.630 1.00 58.12  ? 258 PHE A CE2 1 
ATOM   1171 C  CZ  . PHE A 1 177 ? 128.537 95.823  141.482 1.00 58.12  ? 258 PHE A CZ  1 
ATOM   1172 N  N   . LYS A 1 178 ? 130.054 89.601  138.714 1.00 57.42  ? 259 LYS A N   1 
ATOM   1173 C  CA  . LYS A 1 178 ? 129.874 88.338  138.002 1.00 57.42  ? 259 LYS A CA  1 
ATOM   1174 C  C   . LYS A 1 178 ? 128.668 87.635  138.608 1.00 57.42  ? 259 LYS A C   1 
ATOM   1175 O  O   . LYS A 1 178 ? 128.659 87.358  139.812 1.00 57.42  ? 259 LYS A O   1 
ATOM   1176 C  CB  . LYS A 1 178 ? 131.121 87.468  138.092 1.00 57.42  ? 259 LYS A CB  1 
ATOM   1177 C  CG  . LYS A 1 178 ? 130.947 86.088  137.481 1.00 57.42  ? 259 LYS A CG  1 
ATOM   1178 C  CD  . LYS A 1 178 ? 132.235 85.284  137.538 1.00 57.42  ? 259 LYS A CD  1 
ATOM   1179 C  CE  . LYS A 1 178 ? 132.040 83.895  136.950 1.00 57.42  ? 259 LYS A CE  1 
ATOM   1180 N  NZ  . LYS A 1 178 ? 133.294 83.094  136.988 1.00 57.42  ? 259 LYS A NZ  1 
ATOM   1181 N  N   . GLU A 1 179 ? 127.663 87.354  137.778 1.00 60.42  ? 260 GLU A N   1 
ATOM   1182 C  CA  . GLU A 1 179 ? 126.419 86.722  138.217 1.00 60.42  ? 260 GLU A CA  1 
ATOM   1183 C  C   . GLU A 1 179 ? 125.744 87.518  139.330 1.00 60.42  ? 260 GLU A C   1 
ATOM   1184 O  O   . GLU A 1 179 ? 125.135 86.946  140.237 1.00 60.42  ? 260 GLU A O   1 
ATOM   1185 C  CB  . GLU A 1 179 ? 126.654 85.274  138.661 1.00 60.42  ? 260 GLU A CB  1 
ATOM   1186 C  CG  . GLU A 1 179 ? 127.058 84.337  137.535 1.00 60.42  ? 260 GLU A CG  1 
ATOM   1187 C  CD  . GLU A 1 179 ? 127.298 82.919  138.016 1.00 60.42  ? 260 GLU A CD  1 
ATOM   1188 O  OE1 . GLU A 1 179 ? 127.271 82.694  139.244 1.00 60.42  ? 260 GLU A OE1 1 
ATOM   1189 O  OE2 . GLU A 1 179 ? 127.511 82.030  137.165 1.00 60.42  ? 260 GLU A OE2 1 
ATOM   1190 N  N   . GLY A 1 180 ? 125.846 88.844  139.268 1.00 60.34  ? 261 GLY A N   1 
ATOM   1191 C  CA  . GLY A 1 180 ? 125.275 89.705  140.279 1.00 60.34  ? 261 GLY A CA  1 
ATOM   1192 C  C   . GLY A 1 180 ? 125.987 89.695  141.614 1.00 60.34  ? 261 GLY A C   1 
ATOM   1193 O  O   . GLY A 1 180 ? 125.363 90.024  142.631 1.00 60.34  ? 261 GLY A O   1 
ATOM   1194 N  N   . LYS A 1 181 ? 127.266 89.332  141.651 1.00 59.36  ? 262 LYS A N   1 
ATOM   1195 C  CA  . LYS A 1 181 ? 128.020 89.237  142.892 1.00 59.36  ? 262 LYS A CA  1 
ATOM   1196 C  C   . LYS A 1 181 ? 129.390 89.879  142.717 1.00 59.36  ? 262 LYS A C   1 
ATOM   1197 O  O   . LYS A 1 181 ? 129.898 89.988  141.597 1.00 59.36  ? 262 LYS A O   1 
ATOM   1198 C  CB  . LYS A 1 181 ? 128.168 87.776  143.329 1.00 59.36  ? 262 LYS A CB  1 
ATOM   1199 C  CG  . LYS A 1 181 ? 128.475 87.590  144.808 1.00 59.36  ? 262 LYS A CG  1 
ATOM   1200 C  CD  . LYS A 1 181 ? 129.906 87.131  145.026 1.00 59.36  ? 262 LYS A CD  1 
ATOM   1201 C  CE  . LYS A 1 181 ? 130.171 86.828  146.492 1.00 59.36  ? 262 LYS A CE  1 
ATOM   1202 N  NZ  . LYS A 1 181 ? 131.574 86.386  146.722 1.00 59.36  ? 262 LYS A NZ  1 
ATOM   1203 N  N   . ILE A 1 182 ? 129.981 90.309  143.831 1.00 57.78  ? 263 ILE A N   1 
ATOM   1204 C  CA  . ILE A 1 182 ? 131.258 91.012  143.794 1.00 57.78  ? 263 ILE A CA  1 
ATOM   1205 C  C   . ILE A 1 182 ? 132.416 90.023  143.789 1.00 57.78  ? 263 ILE A C   1 
ATOM   1206 O  O   . ILE A 1 182 ? 132.394 89.003  144.491 1.00 57.78  ? 263 ILE A O   1 
ATOM   1207 C  CB  . ILE A 1 182 ? 131.365 91.991  144.973 1.00 57.78  ? 263 ILE A CB  1 
ATOM   1208 C  CG1 . ILE A 1 182 ? 132.709 92.715  144.931 1.00 57.78  ? 263 ILE A CG1 1 
ATOM   1209 C  CG2 . ILE A 1 182 ? 131.165 91.271  146.300 1.00 57.78  ? 263 ILE A CG2 1 
ATOM   1210 C  CD1 . ILE A 1 182 ? 132.927 93.494  143.682 1.00 57.78  ? 263 ILE A CD1 1 
ATOM   1211 N  N   . GLN A 1 183 ? 133.436 90.323  142.985 1.00 57.30  ? 264 GLN A N   1 
ATOM   1212 C  CA  . GLN A 1 183 ? 134.691 89.584  142.999 1.00 57.30  ? 264 GLN A CA  1 
ATOM   1213 C  C   . GLN A 1 183 ? 135.892 90.449  143.348 1.00 57.30  ? 264 GLN A C   1 
ATOM   1214 O  O   . GLN A 1 183 ? 136.862 89.933  143.915 1.00 57.30  ? 264 GLN A O   1 
ATOM   1215 C  CB  . GLN A 1 183 ? 134.931 88.917  141.641 1.00 57.30  ? 264 GLN A CB  1 
ATOM   1216 C  CG  . GLN A 1 183 ? 134.163 87.625  141.449 1.00 57.30  ? 264 GLN A CG  1 
ATOM   1217 C  CD  . GLN A 1 183 ? 132.707 87.866  141.116 1.00 57.30  ? 264 GLN A CD  1 
ATOM   1218 O  OE1 . GLN A 1 183 ? 132.339 88.938  140.638 1.00 57.30  ? 264 GLN A OE1 1 
ATOM   1219 N  NE2 . GLN A 1 183 ? 131.869 86.867  141.366 1.00 57.30  ? 264 GLN A NE2 1 
ATOM   1220 N  N   . LYS A 1 184 ? 135.858 91.744  143.033 1.00 54.35  ? 265 LYS A N   1 
ATOM   1221 C  CA  . LYS A 1 184 ? 136.969 92.622  143.374 1.00 54.35  ? 265 LYS A CA  1 
ATOM   1222 C  C   . LYS A 1 184 ? 136.534 94.077  143.283 1.00 54.35  ? 265 LYS A C   1 
ATOM   1223 O  O   . LYS A 1 184 ? 135.927 94.492  142.291 1.00 54.35  ? 265 LYS A O   1 
ATOM   1224 C  CB  . LYS A 1 184 ? 138.174 92.382  142.454 1.00 54.35  ? 265 LYS A CB  1 
ATOM   1225 C  CG  . LYS A 1 184 ? 139.486 92.916  143.006 1.00 54.35  ? 265 LYS A CG  1 
ATOM   1226 C  CD  . LYS A 1 184 ? 140.626 92.694  142.029 1.00 54.35  ? 265 LYS A CD  1 
ATOM   1227 C  CE  . LYS A 1 184 ? 141.973 92.767  142.722 1.00 54.35  ? 265 LYS A CE  1 
ATOM   1228 N  NZ  . LYS A 1 184 ? 143.087 92.885  141.742 1.00 54.35  ? 265 LYS A NZ  1 
ATOM   1229 N  N   . ILE A 1 185 ? 136.865 94.845  144.319 1.00 53.53  ? 266 ILE A N   1 
ATOM   1230 C  CA  . ILE A 1 185 ? 136.759 96.300  144.312 1.00 53.53  ? 266 ILE A CA  1 
ATOM   1231 C  C   . ILE A 1 185 ? 138.166 96.844  144.489 1.00 53.53  ? 266 ILE A C   1 
ATOM   1232 O  O   . ILE A 1 185 ? 138.832 96.529  145.484 1.00 53.53  ? 266 ILE A O   1 
ATOM   1233 C  CB  . ILE A 1 185 ? 135.834 96.822  145.423 1.00 53.53  ? 266 ILE A CB  1 
ATOM   1234 C  CG1 . ILE A 1 185 ? 134.415 96.287  145.247 1.00 53.53  ? 266 ILE A CG1 1 
ATOM   1235 C  CG2 . ILE A 1 185 ? 135.826 98.341  145.433 1.00 53.53  ? 266 ILE A CG2 1 
ATOM   1236 C  CD1 . ILE A 1 185 ? 133.472 96.676  146.365 1.00 53.53  ? 266 ILE A CD1 1 
ATOM   1237 N  N   . GLU A 1 186 ? 138.625 97.653  143.538 1.00 55.46  ? 267 GLU A N   1 
ATOM   1238 C  CA  . GLU A 1 186 ? 139.993 98.149  143.595 1.00 55.46  ? 267 GLU A CA  1 
ATOM   1239 C  C   . GLU A 1 186 ? 140.027 99.644  143.307 1.00 55.46  ? 267 GLU A C   1 
ATOM   1240 O  O   . GLU A 1 186 ? 139.263 100.150 142.478 1.00 55.46  ? 267 GLU A O   1 
ATOM   1241 C  CB  . GLU A 1 186 ? 140.901 97.369  142.624 1.00 55.46  ? 267 GLU A CB  1 
ATOM   1242 C  CG  . GLU A 1 186 ? 142.231 98.031  142.290 1.00 55.46  ? 267 GLU A CG  1 
ATOM   1243 C  CD  . GLU A 1 186 ? 142.961 97.334  141.157 1.00 55.46  ? 267 GLU A CD  1 
ATOM   1244 O  OE1 . GLU A 1 186 ? 143.552 98.028  140.305 1.00 55.46  ? 267 GLU A OE1 1 
ATOM   1245 O  OE2 . GLU A 1 186 ? 142.946 96.086  141.123 1.00 55.46  ? 267 GLU A OE2 1 
ATOM   1246 N  N   . GLU A 1 187 ? 140.913 100.344 144.013 1.00 57.53  ? 268 GLU A N   1 
ATOM   1247 C  CA  . GLU A 1 187 ? 141.026 101.789 143.896 1.00 57.53  ? 268 GLU A CA  1 
ATOM   1248 C  C   . GLU A 1 187 ? 141.651 102.174 142.562 1.00 57.53  ? 268 GLU A C   1 
ATOM   1249 O  O   . GLU A 1 187 ? 142.366 101.382 141.942 1.00 57.53  ? 268 GLU A O   1 
ATOM   1250 C  CB  . GLU A 1 187 ? 141.861 102.351 145.046 1.00 57.53  ? 268 GLU A CB  1 
ATOM   1251 C  CG  . GLU A 1 187 ? 141.203 102.216 146.409 1.00 57.53  ? 268 GLU A CG  1 
ATOM   1252 C  CD  . GLU A 1 187 ? 142.062 102.764 147.533 1.00 57.53  ? 268 GLU A CD  1 
ATOM   1253 O  OE1 . GLU A 1 187 ? 143.224 103.138 147.269 1.00 57.53  ? 268 GLU A OE1 1 
ATOM   1254 O  OE2 . GLU A 1 187 ? 141.574 102.818 148.681 1.00 57.53  ? 268 GLU A OE2 1 
ATOM   1255 N  N   . LEU A 1 188 ? 141.373 103.399 142.124 1.00 56.66  ? 269 LEU A N   1 
ATOM   1256 C  CA  . LEU A 1 188 ? 141.866 103.870 140.837 1.00 56.66  ? 269 LEU A CA  1 
ATOM   1257 C  C   . LEU A 1 188 ? 143.381 104.021 140.863 1.00 56.66  ? 269 LEU A C   1 
ATOM   1258 O  O   . LEU A 1 188 ? 143.955 104.497 141.847 1.00 56.66  ? 269 LEU A O   1 
ATOM   1259 C  CB  . LEU A 1 188 ? 141.212 105.201 140.474 1.00 56.66  ? 269 LEU A CB  1 
ATOM   1260 C  CG  . LEU A 1 188 ? 141.303 105.615 139.005 1.00 56.66  ? 269 LEU A CG  1 
ATOM   1261 C  CD1 . LEU A 1 188 ? 140.177 104.987 138.202 1.00 56.66  ? 269 LEU A CD1 1 
ATOM   1262 C  CD2 . LEU A 1 188 ? 141.283 107.129 138.872 1.00 56.66  ? 269 LEU A CD2 1 
ATOM   1263 N  N   . GLN A 1 189 ? 144.024 103.615 139.775 1.00 57.71  ? 270 GLN A N   1 
ATOM   1264 C  CA  . GLN A 1 189 ? 145.459 103.746 139.580 1.00 57.71  ? 270 GLN A CA  1 
ATOM   1265 C  C   . GLN A 1 189 ? 145.730 104.722 138.441 1.00 57.71  ? 270 GLN A C   1 
ATOM   1266 O  O   . GLN A 1 189 ? 144.823 105.375 137.920 1.00 57.71  ? 270 GLN A O   1 
ATOM   1267 C  CB  . GLN A 1 189 ? 146.090 102.381 139.301 1.00 57.71  ? 270 GLN A CB  1 
ATOM   1268 C  CG  . GLN A 1 189 ? 146.026 101.415 140.471 1.00 57.71  ? 270 GLN A CG  1 
ATOM   1269 C  CD  . GLN A 1 189 ? 146.865 100.173 140.246 1.00 57.71  ? 270 GLN A CD  1 
ATOM   1270 O  OE1 . GLN A 1 189 ? 147.467 100.001 139.186 1.00 57.71  ? 270 GLN A OE1 1 
ATOM   1271 N  NE2 . GLN A 1 189 ? 146.909 99.300  141.245 1.00 57.71  ? 270 GLN A NE2 1 
ATOM   1272 N  N   . GLY A 1 190 ? 146.998 104.827 138.064 1.00 60.18  ? 271 GLY A N   1 
ATOM   1273 C  CA  . GLY A 1 190 ? 147.378 105.624 136.914 1.00 60.18  ? 271 GLY A CA  1 
ATOM   1274 C  C   . GLY A 1 190 ? 147.487 107.106 137.217 1.00 60.18  ? 271 GLY A C   1 
ATOM   1275 O  O   . GLY A 1 190 ? 147.602 107.543 138.366 1.00 60.18  ? 271 GLY A O   1 
ATOM   1276 N  N   . ASN A 1 191 ? 147.448 107.894 136.143 1.00 58.95  ? 272 ASN A N   1 
ATOM   1277 C  CA  . ASN A 1 191 ? 147.642 109.334 136.213 1.00 58.95  ? 272 ASN A CA  1 
ATOM   1278 C  C   . ASN A 1 191 ? 146.338 110.119 136.126 1.00 58.95  ? 272 ASN A C   1 
ATOM   1279 O  O   . ASN A 1 191 ? 146.376 111.349 136.019 1.00 58.95  ? 272 ASN A O   1 
ATOM   1280 C  CB  . ASN A 1 191 ? 148.595 109.785 135.106 1.00 58.95  ? 272 ASN A CB  1 
ATOM   1281 C  CG  . ASN A 1 191 ? 150.010 109.288 135.319 1.00 58.95  ? 272 ASN A CG  1 
ATOM   1282 O  OD1 . ASN A 1 191 ? 150.521 109.298 136.438 1.00 58.95  ? 272 ASN A OD1 1 
ATOM   1283 N  ND2 . ASN A 1 191 ? 150.650 108.846 134.243 1.00 58.95  ? 272 ASN A ND2 1 
ATOM   1284 N  N   . ALA A 1 192 ? 145.192 109.445 136.167 1.00 57.36  ? 273 ALA A N   1 
ATOM   1285 C  CA  . ALA A 1 192 ? 143.914 110.142 136.115 1.00 57.36  ? 273 ALA A CA  1 
ATOM   1286 C  C   . ALA A 1 192 ? 143.649 110.876 137.423 1.00 57.36  ? 273 ALA A C   1 
ATOM   1287 O  O   . ALA A 1 192 ? 143.943 110.370 138.509 1.00 57.36  ? 273 ALA A O   1 
ATOM   1288 C  CB  . ALA A 1 192 ? 142.782 109.159 135.825 1.00 57.36  ? 273 ALA A CB  1 
ATOM   1289 N  N   . GLN A 1 193 ? 143.092 112.082 137.314 1.00 57.75  ? 274 GLN A N   1 
ATOM   1290 C  CA  . GLN A 1 193 ? 142.818 112.912 138.481 1.00 57.75  ? 274 GLN A CA  1 
ATOM   1291 C  C   . GLN A 1 193 ? 141.339 113.010 138.825 1.00 57.75  ? 274 GLN A C   1 
ATOM   1292 O  O   . GLN A 1 193 ? 140.998 113.111 140.008 1.00 57.75  ? 274 GLN A O   1 
ATOM   1293 C  CB  . GLN A 1 193 ? 143.379 114.322 138.270 1.00 57.75  ? 274 GLN A CB  1 
ATOM   1294 C  CG  . GLN A 1 193 ? 144.821 114.344 137.791 1.00 57.75  ? 274 GLN A CG  1 
ATOM   1295 C  CD  . GLN A 1 193 ? 145.589 115.544 138.303 1.00 57.75  ? 274 GLN A CD  1 
ATOM   1296 O  OE1 . GLN A 1 193 ? 145.019 116.612 138.524 1.00 57.75  ? 274 GLN A OE1 1 
ATOM   1297 N  NE2 . GLN A 1 193 ? 146.891 115.375 138.494 1.00 57.75  ? 274 GLN A NE2 1 
ATOM   1298 N  N   . HIS A 1 194 ? 140.454 112.985 137.832 1.00 55.48  ? 275 HIS A N   1 
ATOM   1299 C  CA  . HIS A 1 194 ? 139.022 113.074 138.087 1.00 55.48  ? 275 HIS A CA  1 
ATOM   1300 C  C   . HIS A 1 194 ? 138.293 112.241 137.044 1.00 55.48  ? 275 HIS A C   1 
ATOM   1301 O  O   . HIS A 1 194 ? 138.564 112.370 135.847 1.00 55.48  ? 275 HIS A O   1 
ATOM   1302 C  CB  . HIS A 1 194 ? 138.543 114.528 138.050 1.00 55.48  ? 275 HIS A CB  1 
ATOM   1303 C  CG  . HIS A 1 194 ? 137.225 114.747 138.723 1.00 55.48  ? 275 HIS A CG  1 
ATOM   1304 N  ND1 . HIS A 1 194 ? 137.120 115.094 140.052 1.00 55.48  ? 275 HIS A ND1 1 
ATOM   1305 C  CD2 . HIS A 1 194 ? 135.958 114.669 138.253 1.00 55.48  ? 275 HIS A CD2 1 
ATOM   1306 C  CE1 . HIS A 1 194 ? 135.845 115.220 140.372 1.00 55.48  ? 275 HIS A CE1 1 
ATOM   1307 N  NE2 . HIS A 1 194 ? 135.119 114.968 139.298 1.00 55.48  ? 275 HIS A NE2 1 
ATOM   1308 N  N   . ILE A 1 195 ? 137.371 111.398 137.502 1.00 56.57  ? 276 ILE A N   1 
ATOM   1309 C  CA  . ILE A 1 195 ? 136.724 110.389 136.673 1.00 56.57  ? 276 ILE A CA  1 
ATOM   1310 C  C   . ILE A 1 195 ? 135.229 110.386 136.963 1.00 56.57  ? 276 ILE A C   1 
ATOM   1311 O  O   . ILE A 1 195 ? 134.806 110.018 138.064 1.00 56.57  ? 276 ILE A O   1 
ATOM   1312 C  CB  . ILE A 1 195 ? 137.331 108.993 136.931 1.00 56.57  ? 276 ILE A CB  1 
ATOM   1313 C  CG1 . ILE A 1 195 ? 138.819 108.968 136.572 1.00 56.57  ? 276 ILE A CG1 1 
ATOM   1314 C  CG2 . ILE A 1 195 ? 136.576 107.924 136.180 1.00 56.57  ? 276 ILE A CG2 1 
ATOM   1315 C  CD1 . ILE A 1 195 ? 139.098 109.255 135.115 1.00 56.57  ? 276 ILE A CD1 1 
ATOM   1316 N  N   . GLU A 1 196 ? 134.430 110.787 135.973 1.00 58.43  ? 277 GLU A N   1 
ATOM   1317 C  CA  . GLU A 1 196 ? 132.974 110.791 136.119 1.00 58.43  ? 277 GLU A CA  1 
ATOM   1318 C  C   . GLU A 1 196 ? 132.330 110.436 134.787 1.00 58.43  ? 277 GLU A C   1 
ATOM   1319 O  O   . GLU A 1 196 ? 132.824 110.855 133.735 1.00 58.43  ? 277 GLU A O   1 
ATOM   1320 C  CB  . GLU A 1 196 ? 132.469 112.156 136.599 1.00 58.43  ? 277 GLU A CB  1 
ATOM   1321 C  CG  . GLU A 1 196 ? 132.875 112.539 138.010 1.00 58.43  ? 277 GLU A CG  1 
ATOM   1322 C  CD  . GLU A 1 196 ? 132.357 113.906 138.412 1.00 58.43  ? 277 GLU A CD  1 
ATOM   1323 O  OE1 . GLU A 1 196 ? 131.789 114.607 137.547 1.00 58.43  ? 277 GLU A OE1 1 
ATOM   1324 O  OE2 . GLU A 1 196 ? 132.520 114.281 139.592 1.00 58.43  ? 277 GLU A OE2 1 
ATOM   1325 N  N   . GLU A 1 197 ? 131.231 109.677 134.836 1.00 60.66  ? 278 GLU A N   1 
ATOM   1326 C  CA  . GLU A 1 197 ? 130.324 109.476 133.701 1.00 60.66  ? 278 GLU A CA  1 
ATOM   1327 C  C   . GLU A 1 197 ? 131.062 108.901 132.487 1.00 60.66  ? 278 GLU A C   1 
ATOM   1328 O  O   . GLU A 1 197 ? 131.216 109.548 131.449 1.00 60.66  ? 278 GLU A O   1 
ATOM   1329 C  CB  . GLU A 1 197 ? 129.613 110.785 133.340 1.00 60.66  ? 278 GLU A CB  1 
ATOM   1330 C  CG  . GLU A 1 197 ? 128.711 111.328 134.434 1.00 60.66  ? 278 GLU A CG  1 
ATOM   1331 C  CD  . GLU A 1 197 ? 127.907 112.530 133.978 1.00 60.66  ? 278 GLU A CD  1 
ATOM   1332 O  OE1 . GLU A 1 197 ? 128.348 113.216 133.032 1.00 60.66  ? 278 GLU A OE1 1 
ATOM   1333 O  OE2 . GLU A 1 197 ? 126.837 112.790 134.567 1.00 60.66  ? 278 GLU A OE2 1 
ATOM   1334 N  N   . CYS A 1 198 ? 131.517 107.661 132.642 1.00 63.00  ? 279 CYS A N   1 
ATOM   1335 C  CA  . CYS A 1 198 ? 132.426 107.125 131.643 1.00 63.00  ? 279 CYS A CA  1 
ATOM   1336 C  C   . CYS A 1 198 ? 131.714 106.229 130.632 1.00 63.00  ? 279 CYS A C   1 
ATOM   1337 O  O   . CYS A 1 198 ? 130.641 105.679 130.886 1.00 63.00  ? 279 CYS A O   1 
ATOM   1338 C  CB  . CYS A 1 198 ? 133.581 106.386 132.320 1.00 63.00  ? 279 CYS A CB  1 
ATOM   1339 S  SG  . CYS A 1 198 ? 134.497 107.394 133.549 1.00 63.00  ? 279 CYS A SG  1 
ATOM   1340 N  N   . SER A 1 199 ? 132.327 106.111 129.454 1.00 63.04  ? 280 SER A N   1 
ATOM   1341 C  CA  . SER A 1 199 ? 131.820 105.265 128.380 1.00 63.04  ? 280 SER A CA  1 
ATOM   1342 C  C   . SER A 1 199 ? 132.885 104.235 128.037 1.00 63.04  ? 280 SER A C   1 
ATOM   1343 O  O   . SER A 1 199 ? 134.027 104.598 127.738 1.00 63.04  ? 280 SER A O   1 
ATOM   1344 C  CB  . SER A 1 199 ? 131.452 106.095 127.149 1.00 63.04  ? 280 SER A CB  1 
ATOM   1345 O  OG  . SER A 1 199 ? 130.409 107.007 127.445 1.00 63.04  ? 280 SER A OG  1 
ATOM   1346 N  N   . CYS A 1 200 ? 132.510 102.959 128.072 1.00 64.34  ? 281 CYS A N   1 
ATOM   1347 C  CA  . CYS A 1 200 ? 133.450 101.862 127.909 1.00 64.34  ? 281 CYS A CA  1 
ATOM   1348 C  C   . CYS A 1 200 ? 133.094 101.033 126.683 1.00 64.34  ? 281 CYS A C   1 
ATOM   1349 O  O   . CYS A 1 200 ? 131.918 100.777 126.404 1.00 64.34  ? 281 CYS A O   1 
ATOM   1350 C  CB  . CYS A 1 200 ? 133.466 100.960 129.150 1.00 64.34  ? 281 CYS A CB  1 
ATOM   1351 S  SG  . CYS A 1 200 ? 133.879 101.806 130.692 1.00 64.34  ? 281 CYS A SG  1 
ATOM   1352 N  N   . TYR A 1 201 ? 134.126 100.616 125.952 1.00 58.86  ? 282 TYR A N   1 
ATOM   1353 C  CA  . TYR A 1 201 ? 133.962 99.721  124.816 1.00 58.86  ? 282 TYR A CA  1 
ATOM   1354 C  C   . TYR A 1 201 ? 135.012 98.622  124.894 1.00 58.86  ? 282 TYR A C   1 
ATOM   1355 O  O   . TYR A 1 201 ? 136.160 98.865  125.276 1.00 58.86  ? 282 TYR A O   1 
ATOM   1356 C  CB  . TYR A 1 201 ? 134.065 100.472 123.478 1.00 58.86  ? 282 TYR A CB  1 
ATOM   1357 C  CG  . TYR A 1 201 ? 135.464 100.909 123.105 1.00 58.86  ? 282 TYR A CG  1 
ATOM   1358 C  CD1 . TYR A 1 201 ? 135.981 102.109 123.565 1.00 58.86  ? 282 TYR A CD1 1 
ATOM   1359 C  CD2 . TYR A 1 201 ? 136.262 100.125 122.283 1.00 58.86  ? 282 TYR A CD2 1 
ATOM   1360 C  CE1 . TYR A 1 201 ? 137.256 102.513 123.225 1.00 58.86  ? 282 TYR A CE1 1 
ATOM   1361 C  CE2 . TYR A 1 201 ? 137.537 100.520 121.940 1.00 58.86  ? 282 TYR A CE2 1 
ATOM   1362 C  CZ  . TYR A 1 201 ? 138.029 101.715 122.412 1.00 58.86  ? 282 TYR A CZ  1 
ATOM   1363 O  OH  . TYR A 1 201 ? 139.301 102.114 122.070 1.00 58.86  ? 282 TYR A OH  1 
ATOM   1364 N  N   . GLY A 1 202 ? 134.608 97.411  124.528 1.00 61.04  ? 283 GLY A N   1 
ATOM   1365 C  CA  . GLY A 1 202 ? 135.480 96.255  124.589 1.00 61.04  ? 283 GLY A CA  1 
ATOM   1366 C  C   . GLY A 1 202 ? 136.002 95.849  123.223 1.00 61.04  ? 283 GLY A C   1 
ATOM   1367 O  O   . GLY A 1 202 ? 135.291 95.918  122.224 1.00 61.04  ? 283 GLY A O   1 
ATOM   1368 N  N   . ALA A 1 203 ? 137.261 95.415  123.194 1.00 62.37  ? 284 ALA A N   1 
ATOM   1369 C  CA  . ALA A 1 203 ? 137.899 94.988  121.951 1.00 62.37  ? 284 ALA A CA  1 
ATOM   1370 C  C   . ALA A 1 203 ? 139.080 94.098  122.297 1.00 62.37  ? 284 ALA A C   1 
ATOM   1371 O  O   . ALA A 1 203 ? 139.877 94.445  123.175 1.00 62.37  ? 284 ALA A O   1 
ATOM   1372 C  CB  . ALA A 1 203 ? 138.351 96.192  121.124 1.00 62.37  ? 284 ALA A CB  1 
ATOM   1373 N  N   . ALA A 1 204 ? 139.179 92.950  121.626 1.00 62.31  ? 285 ALA A N   1 
ATOM   1374 C  CA  . ALA A 1 204 ? 140.298 92.020  121.763 1.00 62.31  ? 285 ALA A CA  1 
ATOM   1375 C  C   . ALA A 1 204 ? 140.515 91.566  123.203 1.00 62.31  ? 285 ALA A C   1 
ATOM   1376 O  O   . ALA A 1 204 ? 141.641 91.236  123.589 1.00 62.31  ? 285 ALA A O   1 
ATOM   1377 C  CB  . ALA A 1 204 ? 141.591 92.623  121.202 1.00 62.31  ? 285 ALA A CB  1 
ATOM   1378 N  N   . GLY A 1 205 ? 139.457 91.541  124.012 1.00 63.39  ? 286 GLY A N   1 
ATOM   1379 C  CA  . GLY A 1 205 ? 139.557 91.132  125.395 1.00 63.39  ? 286 GLY A CA  1 
ATOM   1380 C  C   . GLY A 1 205 ? 139.886 92.237  126.375 1.00 63.39  ? 286 GLY A C   1 
ATOM   1381 O  O   . GLY A 1 205 ? 139.865 91.991  127.588 1.00 63.39  ? 286 GLY A O   1 
ATOM   1382 N  N   . MET A 1 206 ? 140.189 93.440  125.898 1.00 62.46  ? 287 MET A N   1 
ATOM   1383 C  CA  . MET A 1 206 ? 140.496 94.570  126.762 1.00 62.46  ? 287 MET A CA  1 
ATOM   1384 C  C   . MET A 1 206 ? 139.417 95.635  126.627 1.00 62.46  ? 287 MET A C   1 
ATOM   1385 O  O   . MET A 1 206 ? 138.911 95.884  125.530 1.00 62.46  ? 287 MET A O   1 
ATOM   1386 C  CB  . MET A 1 206 ? 141.864 95.164  126.420 1.00 62.46  ? 287 MET A CB  1 
ATOM   1387 C  CG  . MET A 1 206 ? 143.008 94.169  126.501 1.00 62.46  ? 287 MET A CG  1 
ATOM   1388 S  SD  . MET A 1 206 ? 144.390 94.600  125.426 1.00 62.46  ? 287 MET A SD  1 
ATOM   1389 C  CE  . MET A 1 206 ? 143.833 93.922  123.866 1.00 62.46  ? 287 MET A CE  1 
ATOM   1390 N  N   . ILE A 1 207 ? 139.064 96.262  127.746 1.00 60.78  ? 288 ILE A N   1 
ATOM   1391 C  CA  . ILE A 1 207 ? 138.033 97.292  127.771 1.00 60.78  ? 288 ILE A CA  1 
ATOM   1392 C  C   . ILE A 1 207 ? 138.712 98.648  127.904 1.00 60.78  ? 288 ILE A C   1 
ATOM   1393 O  O   . ILE A 1 207 ? 139.630 98.812  128.714 1.00 60.78  ? 288 ILE A O   1 
ATOM   1394 C  CB  . ILE A 1 207 ? 137.035 97.053  128.917 1.00 60.78  ? 288 ILE A CB  1 
ATOM   1395 C  CG1 . ILE A 1 207 ? 136.298 95.731  128.713 1.00 60.78  ? 288 ILE A CG1 1 
ATOM   1396 C  CG2 . ILE A 1 207 ? 136.039 98.196  129.012 1.00 60.78  ? 288 ILE A CG2 1 
ATOM   1397 C  CD1 . ILE A 1 207 ? 135.695 95.170  129.978 1.00 60.78  ? 288 ILE A CD1 1 
ATOM   1398 N  N   . LYS A 1 208 ? 138.283 99.614  127.099 1.00 60.65  ? 289 LYS A N   1 
ATOM   1399 C  CA  . LYS A 1 208 ? 138.786 100.976 127.187 1.00 60.65  ? 289 LYS A CA  1 
ATOM   1400 C  C   . LYS A 1 208 ? 137.634 101.906 127.537 1.00 60.65  ? 289 LYS A C   1 
ATOM   1401 O  O   . LYS A 1 208 ? 136.583 101.871 126.888 1.00 60.65  ? 289 LYS A O   1 
ATOM   1402 C  CB  . LYS A 1 208 ? 139.455 101.409 125.881 1.00 60.65  ? 289 LYS A CB  1 
ATOM   1403 C  CG  . LYS A 1 208 ? 140.639 100.542 125.488 1.00 60.65  ? 289 LYS A CG  1 
ATOM   1404 C  CD  . LYS A 1 208 ? 141.569 101.270 124.533 1.00 60.65  ? 289 LYS A CD  1 
ATOM   1405 C  CE  . LYS A 1 208 ? 142.252 100.301 123.583 1.00 60.65  ? 289 LYS A CE  1 
ATOM   1406 N  NZ  . LYS A 1 208 ? 143.647 100.719 123.275 1.00 60.65  ? 289 LYS A NZ  1 
ATOM   1407 N  N   . CYS A 1 209 ? 137.837 102.727 128.564 1.00 63.74  ? 290 CYS A N   1 
ATOM   1408 C  CA  . CYS A 1 209 ? 136.824 103.648 129.060 1.00 63.74  ? 290 CYS A CA  1 
ATOM   1409 C  C   . CYS A 1 209 ? 137.333 105.075 128.928 1.00 63.74  ? 290 CYS A C   1 
ATOM   1410 O  O   . CYS A 1 209 ? 138.436 105.390 129.383 1.00 63.74  ? 290 CYS A O   1 
ATOM   1411 C  CB  . CYS A 1 209 ? 136.473 103.346 130.519 1.00 63.74  ? 290 CYS A CB  1 
ATOM   1412 S  SG  . CYS A 1 209 ? 135.899 101.661 130.815 1.00 63.74  ? 290 CYS A SG  1 
ATOM   1413 N  N   . VAL A 1 210 ? 136.525 105.931 128.309 1.00 59.32  ? 291 VAL A N   1 
ATOM   1414 C  CA  . VAL A 1 210 ? 136.856 107.336 128.096 1.00 59.32  ? 291 VAL A CA  1 
ATOM   1415 C  C   . VAL A 1 210 ? 135.734 108.182 128.684 1.00 59.32  ? 291 VAL A C   1 
ATOM   1416 O  O   . VAL A 1 210 ? 134.549 107.838 128.552 1.00 59.32  ? 291 VAL A O   1 
ATOM   1417 C  CB  . VAL A 1 210 ? 137.078 107.645 126.609 1.00 59.32  ? 291 VAL A CB  1 
ATOM   1418 C  CG1 . VAL A 1 210 ? 138.330 106.946 126.113 1.00 59.32  ? 291 VAL A CG1 1 
ATOM   1419 C  CG2 . VAL A 1 210 ? 135.888 107.182 125.802 1.00 59.32  ? 291 VAL A CG2 1 
ATOM   1420 N  N   . CYS A 1 211 ? 136.110 109.258 129.373 1.00 60.06  ? 292 CYS A N   1 
ATOM   1421 C  CA  . CYS A 1 211 ? 135.160 110.114 130.071 1.00 60.06  ? 292 CYS A CA  1 
ATOM   1422 C  C   . CYS A 1 211 ? 135.764 111.455 130.486 1.00 60.06  ? 292 CYS A C   1 
ATOM   1423 O  O   . CYS A 1 211 ? 136.814 111.877 129.999 1.00 60.06  ? 292 CYS A O   1 
ATOM   1424 C  CB  . CYS A 1 211 ? 134.562 109.367 131.255 1.00 60.06  ? 292 CYS A CB  1 
ATOM   1425 S  SG  . CYS A 1 211 ? 135.638 108.770 132.557 1.00 60.06  ? 292 CYS A SG  1 
ATOM   1426 N  N   . ARG A 1 212 ? 135.051 112.128 131.386 1.00 56.11  ? 293 ARG A N   1 
ATOM   1427 C  CA  . ARG A 1 212 ? 135.176 113.553 131.647 1.00 56.11  ? 293 ARG A CA  1 
ATOM   1428 C  C   . ARG A 1 212 ? 136.058 113.830 132.856 1.00 56.11  ? 293 ARG A C   1 
ATOM   1429 O  O   . ARG A 1 212 ? 135.923 113.183 133.900 1.00 56.11  ? 293 ARG A O   1 
ATOM   1430 C  CB  . ARG A 1 212 ? 133.789 114.159 131.879 1.00 56.11  ? 293 ARG A CB  1 
ATOM   1431 C  CG  . ARG A 1 212 ? 133.763 115.655 132.084 1.00 56.11  ? 293 ARG A CG  1 
ATOM   1432 C  CD  . ARG A 1 212 ? 132.332 116.128 132.257 1.00 56.11  ? 293 ARG A CD  1 
ATOM   1433 N  NE  . ARG A 1 212 ? 131.734 115.639 133.493 1.00 56.11  ? 293 ARG A NE  1 
ATOM   1434 C  CZ  . ARG A 1 212 ? 130.454 115.779 133.810 1.00 56.11  ? 293 ARG A CZ  1 
ATOM   1435 N  NH1 . ARG A 1 212 ? 129.604 116.387 132.999 1.00 56.11  ? 293 ARG A NH1 1 
ATOM   1436 N  NH2 . ARG A 1 212 ? 130.016 115.295 134.969 1.00 56.11  ? 293 ARG A NH2 1 
ATOM   1437 N  N   . ASP A 1 213 ? 136.958 114.797 132.703 1.00 56.34  ? 294 ASP A N   1 
ATOM   1438 C  CA  . ASP A 1 213 ? 137.718 115.368 133.814 1.00 56.34  ? 294 ASP A CA  1 
ATOM   1439 C  C   . ASP A 1 213 ? 137.026 116.670 134.198 1.00 56.34  ? 294 ASP A C   1 
ATOM   1440 O  O   . ASP A 1 213 ? 137.273 117.719 133.599 1.00 56.34  ? 294 ASP A O   1 
ATOM   1441 C  CB  . ASP A 1 213 ? 139.175 115.591 133.427 1.00 56.34  ? 294 ASP A CB  1 
ATOM   1442 C  CG  . ASP A 1 213 ? 140.095 115.646 134.628 1.00 56.34  ? 294 ASP A CG  1 
ATOM   1443 O  OD1 . ASP A 1 213 ? 139.805 116.417 135.567 1.00 56.34  ? 294 ASP A OD1 1 
ATOM   1444 O  OD2 . ASP A 1 213 ? 141.108 114.917 134.636 1.00 56.34  ? 294 ASP A OD2 1 
ATOM   1445 N  N   . ASN A 1 214 ? 136.158 116.598 135.203 1.00 56.04  ? 295 ASN A N   1 
ATOM   1446 C  CA  . ASN A 1 214 ? 135.283 117.703 135.566 1.00 56.04  ? 295 ASN A CA  1 
ATOM   1447 C  C   . ASN A 1 214 ? 136.002 118.758 136.402 1.00 56.04  ? 295 ASN A C   1 
ATOM   1448 O  O   . ASN A 1 214 ? 135.508 119.883 136.525 1.00 56.04  ? 295 ASN A O   1 
ATOM   1449 C  CB  . ASN A 1 214 ? 134.066 117.143 136.325 1.00 56.04  ? 295 ASN A CB  1 
ATOM   1450 C  CG  . ASN A 1 214 ? 132.967 118.173 136.565 1.00 56.04  ? 295 ASN A CG  1 
ATOM   1451 O  OD1 . ASN A 1 214 ? 133.079 119.339 136.197 1.00 56.04  ? 295 ASN A OD1 1 
ATOM   1452 N  ND2 . ASN A 1 214 ? 131.885 117.728 137.193 1.00 56.04  ? 295 ASN A ND2 1 
ATOM   1453 N  N   . TRP A 1 215 ? 137.181 118.447 136.939 1.00 58.20  ? 296 TRP A N   1 
ATOM   1454 C  CA  . TRP A 1 215 ? 137.859 119.340 137.874 1.00 58.20  ? 296 TRP A CA  1 
ATOM   1455 C  C   . TRP A 1 215 ? 138.920 120.198 137.191 1.00 58.20  ? 296 TRP A C   1 
ATOM   1456 O  O   . TRP A 1 215 ? 138.813 121.427 137.181 1.00 58.20  ? 296 TRP A O   1 
ATOM   1457 C  CB  . TRP A 1 215 ? 138.480 118.512 139.011 1.00 58.20  ? 296 TRP A CB  1 
ATOM   1458 C  CG  . TRP A 1 215 ? 139.455 119.254 139.895 1.00 58.20  ? 296 TRP A CG  1 
ATOM   1459 C  CD1 . TRP A 1 215 ? 139.477 120.595 140.160 1.00 58.20  ? 296 TRP A CD1 1 
ATOM   1460 C  CD2 . TRP A 1 215 ? 140.549 118.685 140.627 1.00 58.20  ? 296 TRP A CD2 1 
ATOM   1461 N  NE1 . TRP A 1 215 ? 140.515 120.893 141.008 1.00 58.20  ? 296 TRP A NE1 1 
ATOM   1462 C  CE2 . TRP A 1 215 ? 141.188 119.738 141.309 1.00 58.20  ? 296 TRP A CE2 1 
ATOM   1463 C  CE3 . TRP A 1 215 ? 141.049 117.388 140.770 1.00 58.20  ? 296 TRP A CE3 1 
ATOM   1464 C  CZ2 . TRP A 1 215 ? 142.300 119.535 142.122 1.00 58.20  ? 296 TRP A CZ2 1 
ATOM   1465 C  CZ3 . TRP A 1 215 ? 142.153 117.188 141.577 1.00 58.20  ? 296 TRP A CZ3 1 
ATOM   1466 C  CH2 . TRP A 1 215 ? 142.766 118.256 142.242 1.00 58.20  ? 296 TRP A CH2 1 
ATOM   1467 N  N   . LYS A 1 216 ? 139.944 119.574 136.614 1.00 59.80  ? 297 LYS A N   1 
ATOM   1468 C  CA  . LYS A 1 216 ? 141.083 120.316 136.087 1.00 59.80  ? 297 LYS A CA  1 
ATOM   1469 C  C   . LYS A 1 216 ? 141.259 120.164 134.586 1.00 59.80  ? 297 LYS A C   1 
ATOM   1470 O  O   . LYS A 1 216 ? 141.328 121.170 133.869 1.00 59.80  ? 297 LYS A O   1 
ATOM   1471 C  CB  . LYS A 1 216 ? 142.372 119.875 136.799 1.00 59.80  ? 297 LYS A CB  1 
ATOM   1472 C  CG  . LYS A 1 216 ? 142.542 120.441 138.195 1.00 59.80  ? 297 LYS A CG  1 
ATOM   1473 C  CD  . LYS A 1 216 ? 143.946 120.186 138.718 1.00 59.80  ? 297 LYS A CD  1 
ATOM   1474 C  CE  . LYS A 1 216 ? 144.367 121.252 139.715 1.00 59.80  ? 297 LYS A CE  1 
ATOM   1475 N  NZ  . LYS A 1 216 ? 145.175 120.680 140.827 1.00 59.80  ? 297 LYS A NZ  1 
ATOM   1476 N  N   . GLY A 1 217 ? 141.330 118.934 134.086 1.00 57.92  ? 298 GLY A N   1 
ATOM   1477 C  CA  . GLY A 1 217 ? 141.742 118.723 132.718 1.00 57.92  ? 298 GLY A CA  1 
ATOM   1478 C  C   . GLY A 1 217 ? 140.667 119.053 131.704 1.00 57.92  ? 298 GLY A C   1 
ATOM   1479 O  O   . GLY A 1 217 ? 139.468 118.978 131.970 1.00 57.92  ? 298 GLY A O   1 
ATOM   1480 N  N   . ALA A 1 218 ? 141.126 119.431 130.511 1.00 57.79  ? 299 ALA A N   1 
ATOM   1481 C  CA  . ALA A 1 218 ? 140.262 119.584 129.353 1.00 57.79  ? 299 ALA A CA  1 
ATOM   1482 C  C   . ALA A 1 218 ? 140.411 118.449 128.353 1.00 57.79  ? 299 ALA A C   1 
ATOM   1483 O  O   . ALA A 1 218 ? 139.718 118.451 127.330 1.00 57.79  ? 299 ALA A O   1 
ATOM   1484 C  CB  . ALA A 1 218 ? 140.536 120.922 128.650 1.00 57.79  ? 299 ALA A CB  1 
ATOM   1485 N  N   . ASN A 1 219 ? 141.291 117.488 128.618 1.00 55.21  ? 300 ASN A N   1 
ATOM   1486 C  CA  . ASN A 1 219 ? 141.487 116.326 127.764 1.00 55.21  ? 300 ASN A CA  1 
ATOM   1487 C  C   . ASN A 1 219 ? 141.010 115.080 128.496 1.00 55.21  ? 300 ASN A C   1 
ATOM   1488 O  O   . ASN A 1 219 ? 141.276 114.914 129.691 1.00 55.21  ? 300 ASN A O   1 
ATOM   1489 C  CB  . ASN A 1 219 ? 142.954 116.190 127.349 1.00 55.21  ? 300 ASN A CB  1 
ATOM   1490 C  CG  . ASN A 1 219 ? 143.910 116.346 128.514 1.00 55.21  ? 300 ASN A CG  1 
ATOM   1491 O  OD1 . ASN A 1 219 ? 143.495 116.510 129.660 1.00 55.21  ? 300 ASN A OD1 1 
ATOM   1492 N  ND2 . ASN A 1 219 ? 145.204 116.298 128.222 1.00 55.21  ? 300 ASN A ND2 1 
ATOM   1493 N  N   . ARG A 1 220 ? 140.299 114.216 127.778 1.00 53.23  ? 301 ARG A N   1 
ATOM   1494 C  CA  . ARG A 1 220 ? 139.647 113.081 128.404 1.00 53.23  ? 301 ARG A CA  1 
ATOM   1495 C  C   . ARG A 1 220 ? 140.667 112.029 128.836 1.00 53.23  ? 301 ARG A C   1 
ATOM   1496 O  O   . ARG A 1 220 ? 141.595 111.706 128.089 1.00 53.23  ? 301 ARG A O   1 
ATOM   1497 C  CB  . ARG A 1 220 ? 138.641 112.459 127.443 1.00 53.23  ? 301 ARG A CB  1 
ATOM   1498 C  CG  . ARG A 1 220 ? 137.497 113.384 127.095 1.00 53.23  ? 301 ARG A CG  1 
ATOM   1499 C  CD  . ARG A 1 220 ? 136.373 112.654 126.389 1.00 53.23  ? 301 ARG A CD  1 
ATOM   1500 N  NE  . ARG A 1 220 ? 135.305 113.572 126.017 1.00 53.23  ? 301 ARG A NE  1 
ATOM   1501 C  CZ  . ARG A 1 220 ? 134.370 114.010 126.848 1.00 53.23  ? 301 ARG A CZ  1 
ATOM   1502 N  NH1 . ARG A 1 220 ? 134.329 113.617 128.110 1.00 53.23  ? 301 ARG A NH1 1 
ATOM   1503 N  NH2 . ARG A 1 220 ? 133.455 114.864 126.402 1.00 53.23  ? 301 ARG A NH2 1 
ATOM   1504 N  N   . PRO A 1 221 ? 140.521 111.486 130.041 1.00 58.43  ? 302 PRO A N   1 
ATOM   1505 C  CA  . PRO A 1 221 ? 141.335 110.333 130.434 1.00 58.43  ? 302 PRO A CA  1 
ATOM   1506 C  C   . PRO A 1 221 ? 140.827 109.052 129.791 1.00 58.43  ? 302 PRO A C   1 
ATOM   1507 O  O   . PRO A 1 221 ? 139.696 108.966 129.307 1.00 58.43  ? 302 PRO A O   1 
ATOM   1508 C  CB  . PRO A 1 221 ? 141.181 110.283 131.961 1.00 58.43  ? 302 PRO A CB  1 
ATOM   1509 C  CG  . PRO A 1 221 ? 140.432 111.539 132.342 1.00 58.43  ? 302 PRO A CG  1 
ATOM   1510 C  CD  . PRO A 1 221 ? 139.659 111.941 131.139 1.00 58.43  ? 302 PRO A CD  1 
ATOM   1511 N  N   . ILE A 1 222 ? 141.694 108.043 129.793 1.00 58.74  ? 303 ILE A N   1 
ATOM   1512 C  CA  . ILE A 1 222 ? 141.369 106.720 129.275 1.00 58.74  ? 303 ILE A CA  1 
ATOM   1513 C  C   . ILE A 1 222 ? 141.836 105.676 130.281 1.00 58.74  ? 303 ILE A C   1 
ATOM   1514 O  O   . ILE A 1 222 ? 142.935 105.778 130.842 1.00 58.74  ? 303 ILE A O   1 
ATOM   1515 C  CB  . ILE A 1 222 ? 141.984 106.471 127.881 1.00 58.74  ? 303 ILE A CB  1 
ATOM   1516 C  CG1 . ILE A 1 222 ? 141.419 105.187 127.265 1.00 58.74  ? 303 ILE A CG1 1 
ATOM   1517 C  CG2 . ILE A 1 222 ? 143.505 106.451 127.933 1.00 58.74  ? 303 ILE A CG2 1 
ATOM   1518 C  CD1 . ILE A 1 222 ? 141.713 105.031 125.788 1.00 58.74  ? 303 ILE A CD1 1 
ATOM   1519 N  N   . ILE A 1 223 ? 140.985 104.684 130.525 1.00 60.15  ? 304 ILE A N   1 
ATOM   1520 C  CA  . ILE A 1 223 ? 141.251 103.609 131.470 1.00 60.15  ? 304 ILE A CA  1 
ATOM   1521 C  C   . ILE A 1 223 ? 141.227 102.292 130.709 1.00 60.15  ? 304 ILE A C   1 
ATOM   1522 O  O   . ILE A 1 223 ? 140.249 101.989 130.014 1.00 60.15  ? 304 ILE A O   1 
ATOM   1523 C  CB  . ILE A 1 223 ? 140.224 103.596 132.617 1.00 60.15  ? 304 ILE A CB  1 
ATOM   1524 C  CG1 . ILE A 1 223 ? 140.307 104.895 133.420 1.00 60.15  ? 304 ILE A CG1 1 
ATOM   1525 C  CG2 . ILE A 1 223 ? 140.446 102.392 133.520 1.00 60.15  ? 304 ILE A CG2 1 
ATOM   1526 C  CD1 . ILE A 1 223 ? 139.313 104.971 134.558 1.00 60.15  ? 304 ILE A CD1 1 
ATOM   1527 N  N   . THR A 1 224 ? 142.301 101.521 130.836 1.00 59.43  ? 305 THR A N   1 
ATOM   1528 C  CA  . THR A 1 224 ? 142.407 100.200 130.237 1.00 59.43  ? 305 THR A CA  1 
ATOM   1529 C  C   . THR A 1 224 ? 142.147 99.147  131.306 1.00 59.43  ? 305 THR A C   1 
ATOM   1530 O  O   . THR A 1 224 ? 142.833 99.118  132.333 1.00 59.43  ? 305 THR A O   1 
ATOM   1531 C  CB  . THR A 1 224 ? 143.790 99.992  129.617 1.00 59.43  ? 305 THR A CB  1 
ATOM   1532 O  OG1 . THR A 1 224 ? 144.770 99.902  130.658 1.00 59.43  ? 305 THR A OG1 1 
ATOM   1533 C  CG2 . THR A 1 224 ? 144.142 101.156 128.704 1.00 59.43  ? 305 THR A CG2 1 
ATOM   1534 N  N   . ILE A 1 225 ? 141.159 98.289  131.060 1.00 59.18  ? 306 ILE A N   1 
ATOM   1535 C  CA  . ILE A 1 225 ? 140.732 97.258  131.996 1.00 59.18  ? 306 ILE A CA  1 
ATOM   1536 C  C   . ILE A 1 225 ? 140.977 95.899  131.358 1.00 59.18  ? 306 ILE A C   1 
ATOM   1537 O  O   . ILE A 1 225 ? 140.540 95.648  130.226 1.00 59.18  ? 306 ILE A O   1 
ATOM   1538 C  CB  . ILE A 1 225 ? 139.250 97.418  132.383 1.00 59.18  ? 306 ILE A CB  1 
ATOM   1539 C  CG1 . ILE A 1 225 ? 138.996 98.802  132.981 1.00 59.18  ? 306 ILE A CG1 1 
ATOM   1540 C  CG2 . ILE A 1 225 ? 138.835 96.332  133.362 1.00 59.18  ? 306 ILE A CG2 1 
ATOM   1541 C  CD1 . ILE A 1 225 ? 137.559 99.034  133.386 1.00 59.18  ? 306 ILE A CD1 1 
ATOM   1542 N  N   . ASP A 1 226 ? 141.679 95.031  132.084 1.00 62.77  ? 307 ASP A N   1 
ATOM   1543 C  CA  . ASP A 1 226 ? 141.961 93.664  131.664 1.00 62.77  ? 307 ASP A CA  1 
ATOM   1544 C  C   . ASP A 1 226 ? 141.274 92.712  132.633 1.00 62.77  ? 307 ASP A C   1 
ATOM   1545 O  O   . ASP A 1 226 ? 141.749 92.529  133.767 1.00 62.77  ? 307 ASP A O   1 
ATOM   1546 C  CB  . ASP A 1 226 ? 143.471 93.410  131.635 1.00 62.77  ? 307 ASP A CB  1 
ATOM   1547 C  CG  . ASP A 1 226 ? 143.844 92.187  130.820 1.00 62.77  ? 307 ASP A CG  1 
ATOM   1548 O  OD1 . ASP A 1 226 ? 142.970 91.325  130.598 1.00 62.77  ? 307 ASP A OD1 1 
ATOM   1549 O  OD2 . ASP A 1 226 ? 145.016 92.089  130.400 1.00 62.77  ? 307 ASP A OD2 1 
ATOM   1550 N  N   . PRO A 1 227 ? 140.140 92.114  132.258 1.00 61.52  ? 308 PRO A N   1 
ATOM   1551 C  CA  . PRO A 1 227 ? 139.482 91.139  133.136 1.00 61.52  ? 308 PRO A CA  1 
ATOM   1552 C  C   . PRO A 1 227 ? 140.131 89.764  133.141 1.00 61.52  ? 308 PRO A C   1 
ATOM   1553 O  O   . PRO A 1 227 ? 139.689 88.897  133.902 1.00 61.52  ? 308 PRO A O   1 
ATOM   1554 C  CB  . PRO A 1 227 ? 138.055 91.065  132.571 1.00 61.52  ? 308 PRO A CB  1 
ATOM   1555 C  CG  . PRO A 1 227 ? 138.158 91.541  131.174 1.00 61.52  ? 308 PRO A CG  1 
ATOM   1556 C  CD  . PRO A 1 227 ? 139.317 92.480  131.094 1.00 61.52  ? 308 PRO A CD  1 
ATOM   1557 N  N   . GLU A 1 228 ? 141.157 89.533  132.319 1.00 66.49  ? 309 GLU A N   1 
ATOM   1558 C  CA  . GLU A 1 228 ? 141.929 88.299  132.427 1.00 66.49  ? 309 GLU A CA  1 
ATOM   1559 C  C   . GLU A 1 228 ? 142.797 88.319  133.679 1.00 66.49  ? 309 GLU A C   1 
ATOM   1560 O  O   . GLU A 1 228 ? 142.675 87.450  134.549 1.00 66.49  ? 309 GLU A O   1 
ATOM   1561 C  CB  . GLU A 1 228 ? 142.796 88.094  131.180 1.00 66.49  ? 309 GLU A CB  1 
ATOM   1562 C  CG  . GLU A 1 228 ? 142.122 87.347  130.037 1.00 66.49  ? 309 GLU A CG  1 
ATOM   1563 C  CD  . GLU A 1 228 ? 141.442 88.266  129.043 1.00 66.49  ? 309 GLU A CD  1 
ATOM   1564 O  OE1 . GLU A 1 228 ? 141.376 89.486  129.299 1.00 66.49  ? 309 GLU A OE1 1 
ATOM   1565 O  OE2 . GLU A 1 228 ? 140.990 87.765  127.992 1.00 66.49  ? 309 GLU A OE2 1 
ATOM   1566 N  N   . MET A 1 229 ? 143.681 89.310  133.783 1.00 66.12  ? 310 MET A N   1 
ATOM   1567 C  CA  . MET A 1 229 ? 144.474 89.499  134.988 1.00 66.12  ? 310 MET A CA  1 
ATOM   1568 C  C   . MET A 1 229 ? 143.730 90.281  136.059 1.00 66.12  ? 310 MET A C   1 
ATOM   1569 O  O   . MET A 1 229 ? 144.274 90.468  137.153 1.00 66.12  ? 310 MET A O   1 
ATOM   1570 C  CB  . MET A 1 229 ? 145.785 90.212  134.649 1.00 66.12  ? 310 MET A CB  1 
ATOM   1571 C  CG  . MET A 1 229 ? 146.724 89.411  133.757 1.00 66.12  ? 310 MET A CG  1 
ATOM   1572 S  SD  . MET A 1 229 ? 147.275 87.856  134.489 1.00 66.12  ? 310 MET A SD  1 
ATOM   1573 C  CE  . MET A 1 229 ? 146.237 86.672  133.630 1.00 66.12  ? 310 MET A CE  1 
ATOM   1574 N  N   . MET A 1 230 ? 142.512 90.745  135.763 1.00 62.31  ? 311 MET A N   1 
ATOM   1575 C  CA  . MET A 1 230 ? 141.660 91.435  136.731 1.00 62.31  ? 311 MET A CA  1 
ATOM   1576 C  C   . MET A 1 230 ? 142.362 92.685  137.266 1.00 62.31  ? 311 MET A C   1 
ATOM   1577 O  O   . MET A 1 230 ? 142.663 92.802  138.456 1.00 62.31  ? 311 MET A O   1 
ATOM   1578 C  CB  . MET A 1 230 ? 141.253 90.484  137.863 1.00 62.31  ? 311 MET A CB  1 
ATOM   1579 C  CG  . MET A 1 230 ? 140.262 91.041  138.868 1.00 62.31  ? 311 MET A CG  1 
ATOM   1580 S  SD  . MET A 1 230 ? 138.679 91.416  138.108 1.00 62.31  ? 311 MET A SD  1 
ATOM   1581 C  CE  . MET A 1 230 ? 138.044 89.765  137.837 1.00 62.31  ? 311 MET A CE  1 
ATOM   1582 N  N   . THR A 1 231 ? 142.656 93.618  136.361 1.00 59.50  ? 312 THR A N   1 
ATOM   1583 C  CA  . THR A 1 231 ? 143.433 94.801  136.709 1.00 59.50  ? 312 THR A CA  1 
ATOM   1584 C  C   . THR A 1 231 ? 143.028 95.946  135.789 1.00 59.50  ? 312 THR A C   1 
ATOM   1585 O  O   . THR A 1 231 ? 142.322 95.739  134.800 1.00 59.50  ? 312 THR A O   1 
ATOM   1586 C  CB  . THR A 1 231 ? 144.946 94.516  136.598 1.00 59.50  ? 312 THR A CB  1 
ATOM   1587 O  OG1 . THR A 1 231 ? 145.242 93.267  137.234 1.00 59.50  ? 312 THR A OG1 1 
ATOM   1588 C  CG2 . THR A 1 231 ? 145.771 95.594  137.294 1.00 59.50  ? 312 THR A CG2 1 
ATOM   1589 N  N   . HIS A 1 232 ? 143.452 97.163  136.132 1.00 58.50  ? 313 HIS A N   1 
ATOM   1590 C  CA  . HIS A 1 232 ? 143.272 98.311  135.258 1.00 58.50  ? 313 HIS A CA  1 
ATOM   1591 C  C   . HIS A 1 232 ? 144.445 99.271  135.392 1.00 58.50  ? 313 HIS A C   1 
ATOM   1592 O  O   . HIS A 1 232 ? 145.258 99.169  136.314 1.00 58.50  ? 313 HIS A O   1 
ATOM   1593 C  CB  . HIS A 1 232 ? 141.976 99.075  135.550 1.00 58.50  ? 313 HIS A CB  1 
ATOM   1594 C  CG  . HIS A 1 232 ? 141.942 99.717  136.900 1.00 58.50  ? 313 HIS A CG  1 
ATOM   1595 N  ND1 . HIS A 1 232 ? 141.630 99.025  138.049 1.00 58.50  ? 313 HIS A ND1 1 
ATOM   1596 C  CD2 . HIS A 1 232 ? 142.196 100.991 137.286 1.00 58.50  ? 313 HIS A CD2 1 
ATOM   1597 C  CE1 . HIS A 1 232 ? 141.677 99.846  139.083 1.00 58.50  ? 313 HIS A CE1 1 
ATOM   1598 N  NE2 . HIS A 1 232 ? 142.021 101.045 138.647 1.00 58.50  ? 313 HIS A NE2 1 
ATOM   1599 N  N   . THR A 1 233 ? 144.515 100.202 134.445 1.00 59.38  ? 314 THR A N   1 
ATOM   1600 C  CA  . THR A 1 233 ? 145.506 101.267 134.433 1.00 59.38  ? 314 THR A CA  1 
ATOM   1601 C  C   . THR A 1 233 ? 144.852 102.502 133.827 1.00 59.38  ? 314 THR A C   1 
ATOM   1602 O  O   . THR A 1 233 ? 143.927 102.390 133.022 1.00 59.38  ? 314 THR A O   1 
ATOM   1603 C  CB  . THR A 1 233 ? 146.760 100.851 133.639 1.00 59.38  ? 314 THR A CB  1 
ATOM   1604 O  OG1 . THR A 1 233 ? 147.360 99.711  134.264 1.00 59.38  ? 314 THR A OG1 1 
ATOM   1605 C  CG2 . THR A 1 233 ? 147.789 101.973 133.593 1.00 59.38  ? 314 THR A CG2 1 
ATOM   1606 N  N   . SER A 1 234 ? 145.312 103.684 134.231 1.00 60.54  ? 315 SER A N   1 
ATOM   1607 C  CA  . SER A 1 234 ? 144.713 104.929 133.771 1.00 60.54  ? 315 SER A CA  1 
ATOM   1608 C  C   . SER A 1 234 ? 145.780 105.857 133.213 1.00 60.54  ? 315 SER A C   1 
ATOM   1609 O  O   . SER A 1 234 ? 146.918 105.870 133.691 1.00 60.54  ? 315 SER A O   1 
ATOM   1610 C  CB  . SER A 1 234 ? 143.959 105.634 134.902 1.00 60.54  ? 315 SER A CB  1 
ATOM   1611 O  OG  . SER A 1 234 ? 142.863 104.857 135.350 1.00 60.54  ? 315 SER A OG  1 
ATOM   1612 N  N   . LYS A 1 235 ? 145.403 106.631 132.199 1.00 58.45  ? 316 LYS A N   1 
ATOM   1613 C  CA  . LYS A 1 235 ? 146.270 107.654 131.630 1.00 58.45  ? 316 LYS A CA  1 
ATOM   1614 C  C   . LYS A 1 235 ? 145.383 108.663 130.913 1.00 58.45  ? 316 LYS A C   1 
ATOM   1615 O  O   . LYS A 1 235 ? 144.163 108.668 131.081 1.00 58.45  ? 316 LYS A O   1 
ATOM   1616 C  CB  . LYS A 1 235 ? 147.317 107.044 130.695 1.00 58.45  ? 316 LYS A CB  1 
ATOM   1617 C  CG  . LYS A 1 235 ? 146.733 106.259 129.535 1.00 58.45  ? 316 LYS A CG  1 
ATOM   1618 C  CD  . LYS A 1 235 ? 147.824 105.581 128.723 1.00 58.45  ? 316 LYS A CD  1 
ATOM   1619 C  CE  . LYS A 1 235 ? 147.241 104.799 127.558 1.00 58.45  ? 316 LYS A CE  1 
ATOM   1620 N  NZ  . LYS A 1 235 ? 146.390 103.668 128.021 1.00 58.45  ? 316 LYS A NZ  1 
ATOM   1621 N  N   . TYR A 1 236 ? 146.001 109.519 130.108 1.00 59.24  ? 317 TYR A N   1 
ATOM   1622 C  CA  . TYR A 1 236 ? 145.278 110.519 129.337 1.00 59.24  ? 317 TYR A CA  1 
ATOM   1623 C  C   . TYR A 1 236 ? 145.399 110.226 127.845 1.00 59.24  ? 317 TYR A C   1 
ATOM   1624 O  O   . TYR A 1 236 ? 146.084 109.292 127.420 1.00 59.24  ? 317 TYR A O   1 
ATOM   1625 C  CB  . TYR A 1 236 ? 145.796 111.926 129.650 1.00 59.24  ? 317 TYR A CB  1 
ATOM   1626 C  CG  . TYR A 1 236 ? 145.334 112.483 130.976 1.00 59.24  ? 317 TYR A CG  1 
ATOM   1627 C  CD1 . TYR A 1 236 ? 144.237 111.949 131.632 1.00 59.24  ? 317 TYR A CD1 1 
ATOM   1628 C  CD2 . TYR A 1 236 ? 146.002 113.542 131.574 1.00 59.24  ? 317 TYR A CD2 1 
ATOM   1629 C  CE1 . TYR A 1 236 ? 143.814 112.457 132.844 1.00 59.24  ? 317 TYR A CE1 1 
ATOM   1630 C  CE2 . TYR A 1 236 ? 145.586 114.054 132.786 1.00 59.24  ? 317 TYR A CE2 1 
ATOM   1631 C  CZ  . TYR A 1 236 ? 144.491 113.509 133.416 1.00 59.24  ? 317 TYR A CZ  1 
ATOM   1632 O  OH  . TYR A 1 236 ? 144.073 114.015 134.624 1.00 59.24  ? 317 TYR A OH  1 
ATOM   1633 N  N   . LEU A 1 237 ? 144.715 111.044 127.047 1.00 57.81  ? 318 LEU A N   1 
ATOM   1634 C  CA  . LEU A 1 237 ? 144.766 110.940 125.594 1.00 57.81  ? 318 LEU A CA  1 
ATOM   1635 C  C   . LEU A 1 237 ? 145.872 111.836 125.054 1.00 57.81  ? 318 LEU A C   1 
ATOM   1636 O  O   . LEU A 1 237 ? 145.931 113.026 125.382 1.00 57.81  ? 318 LEU A O   1 
ATOM   1637 C  CB  . LEU A 1 237 ? 143.423 111.326 124.975 1.00 57.81  ? 318 LEU A CB  1 
ATOM   1638 C  CG  . LEU A 1 237 ? 142.491 110.179 124.581 1.00 57.81  ? 318 LEU A CG  1 
ATOM   1639 C  CD1 . LEU A 1 237 ? 141.962 109.465 125.809 1.00 57.81  ? 318 LEU A CD1 1 
ATOM   1640 C  CD2 . LEU A 1 237 ? 141.344 110.693 123.727 1.00 57.81  ? 318 LEU A CD2 1 
ATOM   1641 N  N   . CYS A 1 238 ? 146.749 111.263 124.228 1.00 61.30  ? 319 CYS A N   1 
ATOM   1642 C  CA  . CYS A 1 238 ? 147.895 112.002 123.715 1.00 61.30  ? 319 CYS A CA  1 
ATOM   1643 C  C   . CYS A 1 238 ? 147.548 112.893 122.530 1.00 61.30  ? 319 CYS A C   1 
ATOM   1644 O  O   . CYS A 1 238 ? 148.394 113.688 122.108 1.00 61.30  ? 319 CYS A O   1 
ATOM   1645 C  CB  . CYS A 1 238 ? 149.013 111.032 123.312 1.00 61.30  ? 319 CYS A CB  1 
ATOM   1646 S  SG  . CYS A 1 238 ? 149.478 109.776 124.552 1.00 61.30  ? 319 CYS A SG  1 
ATOM   1647 N  N   . SER A 1 239 ? 146.334 112.786 121.993 1.00 59.83  ? 320 SER A N   1 
ATOM   1648 C  CA  . SER A 1 239 ? 145.955 113.570 120.826 1.00 59.83  ? 320 SER A CA  1 
ATOM   1649 C  C   . SER A 1 239 ? 145.899 115.053 121.171 1.00 59.83  ? 320 SER A C   1 
ATOM   1650 O  O   . SER A 1 239 ? 145.447 115.434 122.254 1.00 59.83  ? 320 SER A O   1 
ATOM   1651 C  CB  . SER A 1 239 ? 144.602 113.103 120.292 1.00 59.83  ? 320 SER A CB  1 
ATOM   1652 O  OG  . SER A 1 239 ? 143.545 113.570 121.110 1.00 59.83  ? 320 SER A OG  1 
ATOM   1653 N  N   . LYS A 1 240 ? 146.360 115.891 120.240 1.00 56.79  ? 321 LYS A N   1 
ATOM   1654 C  CA  . LYS A 1 240 ? 146.320 117.332 120.450 1.00 56.79  ? 321 LYS A CA  1 
ATOM   1655 C  C   . LYS A 1 240 ? 144.933 117.911 120.215 1.00 56.79  ? 321 LYS A C   1 
ATOM   1656 O  O   . LYS A 1 240 ? 144.689 119.069 120.569 1.00 56.79  ? 321 LYS A O   1 
ATOM   1657 C  CB  . LYS A 1 240 ? 147.341 118.023 119.545 1.00 56.79  ? 321 LYS A CB  1 
ATOM   1658 C  CG  . LYS A 1 240 ? 146.795 118.461 118.195 1.00 56.79  ? 321 LYS A CG  1 
ATOM   1659 C  CD  . LYS A 1 240 ? 147.875 119.135 117.362 1.00 56.79  ? 321 LYS A CD  1 
ATOM   1660 C  CE  . LYS A 1 240 ? 147.564 119.054 115.877 1.00 56.79  ? 321 LYS A CE  1 
ATOM   1661 N  NZ  . LYS A 1 240 ? 148.786 119.233 115.045 1.00 56.79  ? 321 LYS A NZ  1 
ATOM   1662 N  N   . ILE A 1 241 ? 144.022 117.134 119.632 1.00 54.16  ? 322 ILE A N   1 
ATOM   1663 C  CA  . ILE A 1 241 ? 142.652 117.579 119.391 1.00 54.16  ? 322 ILE A CA  1 
ATOM   1664 C  C   . ILE A 1 241 ? 141.862 117.338 120.675 1.00 54.16  ? 322 ILE A C   1 
ATOM   1665 O  O   . ILE A 1 241 ? 141.465 116.210 120.971 1.00 54.16  ? 322 ILE A O   1 
ATOM   1666 C  CB  . ILE A 1 241 ? 142.021 116.860 118.197 1.00 54.16  ? 322 ILE A CB  1 
ATOM   1667 C  CG1 . ILE A 1 241 ? 142.844 117.110 116.933 1.00 54.16  ? 322 ILE A CG1 1 
ATOM   1668 C  CG2 . ILE A 1 241 ? 140.586 117.312 118.001 1.00 54.16  ? 322 ILE A CG2 1 
ATOM   1669 C  CD1 . ILE A 1 241 ? 142.934 118.568 116.541 1.00 54.16  ? 322 ILE A CD1 1 
ATOM   1670 N  N   . LEU A 1 242 ? 141.639 118.400 121.445 1.00 52.98  ? 323 LEU A N   1 
ATOM   1671 C  CA  . LEU A 1 242 ? 140.851 118.288 122.663 1.00 52.98  ? 323 LEU A CA  1 
ATOM   1672 C  C   . LEU A 1 242 ? 139.401 117.972 122.322 1.00 52.98  ? 323 LEU A C   1 
ATOM   1673 O  O   . LEU A 1 242 ? 138.882 118.404 121.290 1.00 52.98  ? 323 LEU A O   1 
ATOM   1674 C  CB  . LEU A 1 242 ? 140.938 119.582 123.470 1.00 52.98  ? 323 LEU A CB  1 
ATOM   1675 C  CG  . LEU A 1 242 ? 142.345 120.122 123.734 1.00 52.98  ? 323 LEU A CG  1 
ATOM   1676 C  CD1 . LEU A 1 242 ? 142.294 121.325 124.660 1.00 52.98  ? 323 LEU A CD1 1 
ATOM   1677 C  CD2 . LEU A 1 242 ? 143.242 119.040 124.310 1.00 52.98  ? 323 LEU A CD2 1 
ATOM   1678 N  N   . THR A 1 243 ? 138.745 117.214 123.196 1.00 52.25  ? 324 THR A N   1 
ATOM   1679 C  CA  . THR A 1 243 ? 137.395 116.716 122.947 1.00 52.25  ? 324 THR A CA  1 
ATOM   1680 C  C   . THR A 1 243 ? 136.500 116.927 124.168 1.00 52.25  ? 324 THR A C   1 
ATOM   1681 O  O   . THR A 1 243 ? 135.700 116.069 124.549 1.00 52.25  ? 324 THR A O   1 
ATOM   1682 C  CB  . THR A 1 243 ? 137.453 115.249 122.517 1.00 52.25  ? 324 THR A CB  1 
ATOM   1683 O  OG1 . THR A 1 243 ? 136.149 114.804 122.118 1.00 52.25  ? 324 THR A OG1 1 
ATOM   1684 C  CG2 . THR A 1 243 ? 138.018 114.357 123.623 1.00 52.25  ? 324 THR A CG2 1 
ATOM   1685 N  N   . ASP A 1 244 ? 136.599 118.106 124.778 1.00 55.25  ? 325 ASP A N   1 
ATOM   1686 C  CA  . ASP A 1 244 ? 135.766 118.454 125.920 1.00 55.25  ? 325 ASP A CA  1 
ATOM   1687 C  C   . ASP A 1 244 ? 135.240 119.872 125.748 1.00 55.25  ? 325 ASP A C   1 
ATOM   1688 O  O   . ASP A 1 244 ? 135.829 120.694 125.044 1.00 55.25  ? 325 ASP A O   1 
ATOM   1689 C  CB  . ASP A 1 244 ? 136.536 118.331 127.241 1.00 55.25  ? 325 ASP A CB  1 
ATOM   1690 C  CG  . ASP A 1 244 ? 135.654 117.888 128.390 1.00 55.25  ? 325 ASP A CG  1 
ATOM   1691 O  OD1 . ASP A 1 244 ? 134.427 117.771 128.188 1.00 55.25  ? 325 ASP A OD1 1 
ATOM   1692 O  OD2 . ASP A 1 244 ? 136.186 117.657 129.496 1.00 55.25  ? 325 ASP A OD2 1 
ATOM   1693 N  N   . THR A 1 245 ? 134.112 120.149 126.398 1.00 54.42  ? 326 THR A N   1 
ATOM   1694 C  CA  . THR A 1 245 ? 133.495 121.471 126.380 1.00 54.42  ? 326 THR A CA  1 
ATOM   1695 C  C   . THR A 1 245 ? 133.250 121.905 127.816 1.00 54.42  ? 326 THR A C   1 
ATOM   1696 O  O   . THR A 1 245 ? 132.514 121.235 128.546 1.00 54.42  ? 326 THR A O   1 
ATOM   1697 C  CB  . THR A 1 245 ? 132.183 121.463 125.590 1.00 54.42  ? 326 THR A CB  1 
ATOM   1698 O  OG1 . THR A 1 245 ? 132.347 120.682 124.400 1.00 54.42  ? 326 THR A OG1 1 
ATOM   1699 C  CG2 . THR A 1 245 ? 131.779 122.879 125.208 1.00 54.42  ? 326 THR A CG2 1 
ATOM   1700 N  N   . SER A 1 246 ? 133.841 123.029 128.217 1.00 52.91  ? 327 SER A N   1 
ATOM   1701 C  CA  . SER A 1 246 ? 134.604 123.892 127.321 1.00 52.91  ? 327 SER A CA  1 
ATOM   1702 C  C   . SER A 1 246 ? 136.071 123.488 127.226 1.00 52.91  ? 327 SER A C   1 
ATOM   1703 O  O   . SER A 1 246 ? 136.538 122.618 127.960 1.00 52.91  ? 327 SER A O   1 
ATOM   1704 C  CB  . SER A 1 246 ? 134.499 125.347 127.780 1.00 52.91  ? 327 SER A CB  1 
ATOM   1705 O  OG  . SER A 1 246 ? 135.129 125.533 129.036 1.00 52.91  ? 327 SER A OG  1 
ATOM   1706 N  N   . ARG A 1 247 ? 136.792 124.134 126.312 1.00 51.34  ? 328 ARG A N   1 
ATOM   1707 C  CA  . ARG A 1 247 ? 138.196 123.835 126.069 1.00 51.34  ? 328 ARG A CA  1 
ATOM   1708 C  C   . ARG A 1 247 ? 138.842 125.055 125.439 1.00 51.34  ? 328 ARG A C   1 
ATOM   1709 O  O   . ARG A 1 247 ? 138.140 125.890 124.859 1.00 51.34  ? 328 ARG A O   1 
ATOM   1710 C  CB  . ARG A 1 247 ? 138.353 122.620 125.144 1.00 51.34  ? 328 ARG A CB  1 
ATOM   1711 C  CG  . ARG A 1 247 ? 137.845 122.865 123.731 1.00 51.34  ? 328 ARG A CG  1 
ATOM   1712 C  CD  . ARG A 1 247 ? 137.908 121.611 122.878 1.00 51.34  ? 328 ARG A CD  1 
ATOM   1713 N  NE  . ARG A 1 247 ? 137.496 121.871 121.504 1.00 51.34  ? 328 ARG A NE  1 
ATOM   1714 C  CZ  . ARG A 1 247 ? 136.241 121.824 121.079 1.00 51.34  ? 328 ARG A CZ  1 
ATOM   1715 N  NH1 . ARG A 1 247 ? 135.246 121.518 121.894 1.00 51.34  ? 328 ARG A NH1 1 
ATOM   1716 N  NH2 . ARG A 1 247 ? 135.979 122.089 119.802 1.00 51.34  ? 328 ARG A NH2 1 
ATOM   1717 N  N   . PRO A 1 248 ? 140.162 125.192 125.535 1.00 54.03  ? 329 PRO A N   1 
ATOM   1718 C  CA  . PRO A 1 248 ? 140.846 126.247 124.779 1.00 54.03  ? 329 PRO A CA  1 
ATOM   1719 C  C   . PRO A 1 248 ? 141.125 125.812 123.351 1.00 54.03  ? 329 PRO A C   1 
ATOM   1720 O  O   . PRO A 1 248 ? 140.681 124.740 122.927 1.00 54.03  ? 329 PRO A O   1 
ATOM   1721 C  CB  . PRO A 1 248 ? 142.140 126.457 125.571 1.00 54.03  ? 329 PRO A CB  1 
ATOM   1722 C  CG  . PRO A 1 248 ? 142.417 125.119 126.164 1.00 54.03  ? 329 PRO A CG  1 
ATOM   1723 C  CD  . PRO A 1 248 ? 141.077 124.485 126.449 1.00 54.03  ? 329 PRO A CD  1 
ATOM   1724 N  N   . ASN A 1 249 ? 141.849 126.635 122.599 1.00 60.69  ? 330 ASN A N   1 
ATOM   1725 C  CA  . ASN A 1 249 ? 142.287 126.226 121.273 1.00 60.69  ? 330 ASN A CA  1 
ATOM   1726 C  C   . ASN A 1 249 ? 143.224 125.029 121.381 1.00 60.69  ? 330 ASN A C   1 
ATOM   1727 O  O   . ASN A 1 249 ? 143.961 124.876 122.359 1.00 60.69  ? 330 ASN A O   1 
ATOM   1728 C  CB  . ASN A 1 249 ? 142.984 127.384 120.559 1.00 60.69  ? 330 ASN A CB  1 
ATOM   1729 C  CG  . ASN A 1 249 ? 142.126 128.632 120.499 1.00 60.69  ? 330 ASN A CG  1 
ATOM   1730 O  OD1 . ASN A 1 249 ? 140.899 128.560 120.574 1.00 60.69  ? 330 ASN A OD1 1 
ATOM   1731 N  ND2 . ASN A 1 249 ? 142.768 129.786 120.363 1.00 60.69  ? 330 ASN A ND2 1 
ATOM   1732 N  N   . ASP A 1 250 ? 143.179 124.169 120.372 1.00 58.07  ? 331 ASP A N   1 
ATOM   1733 C  CA  . ASP A 1 250 ? 143.943 122.929 120.399 1.00 58.07  ? 331 ASP A CA  1 
ATOM   1734 C  C   . ASP A 1 250 ? 145.435 123.226 120.492 1.00 58.07  ? 331 ASP A C   1 
ATOM   1735 O  O   . ASP A 1 250 ? 145.972 123.943 119.633 1.00 58.07  ? 331 ASP A O   1 
ATOM   1736 C  CB  . ASP A 1 250 ? 143.647 122.096 119.155 1.00 58.07  ? 331 ASP A CB  1 
ATOM   1737 C  CG  . ASP A 1 250 ? 142.181 121.727 119.035 1.00 58.07  ? 331 ASP A CG  1 
ATOM   1738 O  OD1 . ASP A 1 250 ? 141.495 121.664 120.077 1.00 58.07  ? 331 ASP A OD1 1 
ATOM   1739 O  OD2 . ASP A 1 250 ? 141.713 121.502 117.899 1.00 58.07  ? 331 ASP A OD2 1 
ATOM   1740 N  N   . PRO A 1 251 ? 146.135 122.709 121.498 1.00 56.47  ? 332 PRO A N   1 
ATOM   1741 C  CA  . PRO A 1 251 ? 147.569 122.982 121.618 1.00 56.47  ? 332 PRO A CA  1 
ATOM   1742 C  C   . PRO A 1 251 ? 148.372 122.225 120.573 1.00 56.47  ? 332 PRO A C   1 
ATOM   1743 O  O   . PRO A 1 251 ? 147.909 121.256 119.966 1.00 56.47  ? 332 PRO A O   1 
ATOM   1744 C  CB  . PRO A 1 251 ? 147.905 122.501 123.032 1.00 56.47  ? 332 PRO A CB  1 
ATOM   1745 C  CG  . PRO A 1 251 ? 146.887 121.450 123.315 1.00 56.47  ? 332 PRO A CG  1 
ATOM   1746 C  CD  . PRO A 1 251 ? 145.631 121.878 122.605 1.00 56.47  ? 332 PRO A CD  1 
ATOM   1747 N  N   . THR A 1 252 ? 149.602 122.697 120.364 1.00 58.10  ? 333 THR A N   1 
ATOM   1748 C  CA  . THR A 1 252 ? 150.483 122.059 119.391 1.00 58.10  ? 333 THR A CA  1 
ATOM   1749 C  C   . THR A 1 252 ? 150.827 120.633 119.803 1.00 58.10  ? 333 THR A C   1 
ATOM   1750 O  O   . THR A 1 252 ? 150.856 119.726 118.963 1.00 58.10  ? 333 THR A O   1 
ATOM   1751 C  CB  . THR A 1 252 ? 151.758 122.884 119.216 1.00 58.10  ? 333 THR A CB  1 
ATOM   1752 O  OG1 . THR A 1 252 ? 152.464 122.949 120.461 1.00 58.10  ? 333 THR A OG1 1 
ATOM   1753 C  CG2 . THR A 1 252 ? 151.420 124.295 118.759 1.00 58.10  ? 333 THR A CG2 1 
ATOM   1754 N  N   . ASN A 1 253 ? 151.091 120.414 121.089 1.00 57.32  ? 334 ASN A N   1 
ATOM   1755 C  CA  . ASN A 1 253 ? 151.515 119.114 121.604 1.00 57.32  ? 334 ASN A CA  1 
ATOM   1756 C  C   . ASN A 1 253 ? 150.553 118.682 122.705 1.00 57.32  ? 334 ASN A C   1 
ATOM   1757 O  O   . ASN A 1 253 ? 150.755 119.014 123.877 1.00 57.32  ? 334 ASN A O   1 
ATOM   1758 C  CB  . ASN A 1 253 ? 152.949 119.176 122.121 1.00 57.32  ? 334 ASN A CB  1 
ATOM   1759 C  CG  . ASN A 1 253 ? 153.971 119.189 121.004 1.00 57.32  ? 334 ASN A CG  1 
ATOM   1760 O  OD1 . ASN A 1 253 ? 154.643 118.191 120.752 1.00 57.32  ? 334 ASN A OD1 1 
ATOM   1761 N  ND2 . ASN A 1 253 ? 154.092 120.324 120.326 1.00 57.32  ? 334 ASN A ND2 1 
ATOM   1762 N  N   . GLY A 1 254 ? 149.508 117.950 122.329 1.00 59.46  ? 335 GLY A N   1 
ATOM   1763 C  CA  . GLY A 1 254 ? 148.631 117.366 123.323 1.00 59.46  ? 335 GLY A CA  1 
ATOM   1764 C  C   . GLY A 1 254 ? 149.366 116.380 124.210 1.00 59.46  ? 335 GLY A C   1 
ATOM   1765 O  O   . GLY A 1 254 ? 150.048 115.468 123.741 1.00 59.46  ? 335 GLY A O   1 
ATOM   1766 N  N   . ASN A 1 255 ? 149.223 116.569 125.518 1.00 61.79  ? 336 ASN A N   1 
ATOM   1767 C  CA  . ASN A 1 255 ? 149.935 115.775 126.508 1.00 61.79  ? 336 ASN A CA  1 
ATOM   1768 C  C   . ASN A 1 255 ? 148.996 114.744 127.115 1.00 61.79  ? 336 ASN A C   1 
ATOM   1769 O  O   . ASN A 1 255 ? 147.807 115.013 127.316 1.00 61.79  ? 336 ASN A O   1 
ATOM   1770 C  CB  . ASN A 1 255 ? 150.524 116.660 127.610 1.00 61.79  ? 336 ASN A CB  1 
ATOM   1771 C  CG  . ASN A 1 255 ? 151.456 115.899 128.531 1.00 61.79  ? 336 ASN A CG  1 
ATOM   1772 O  OD1 . ASN A 1 255 ? 151.946 114.825 128.185 1.00 61.79  ? 336 ASN A OD1 1 
ATOM   1773 N  ND2 . ASN A 1 255 ? 151.706 116.453 129.711 1.00 61.79  ? 336 ASN A ND2 1 
ATOM   1774 N  N   . CYS A 1 256 ? 149.540 113.560 127.405 1.00 62.92  ? 337 CYS A N   1 
ATOM   1775 C  CA  . CYS A 1 256 ? 148.763 112.471 127.985 1.00 62.92  ? 337 CYS A CA  1 
ATOM   1776 C  C   . CYS A 1 256 ? 149.344 111.971 129.303 1.00 62.92  ? 337 CYS A C   1 
ATOM   1777 O  O   . CYS A 1 256 ? 149.111 110.817 129.679 1.00 62.92  ? 337 CYS A O   1 
ATOM   1778 C  CB  . CYS A 1 256 ? 148.619 111.319 126.991 1.00 62.92  ? 337 CYS A CB  1 
ATOM   1779 S  SG  . CYS A 1 256 ? 150.140 110.792 126.185 1.00 62.92  ? 337 CYS A SG  1 
ATOM   1780 N  N   . ASP A 1 257 ? 150.090 112.813 130.012 1.00 64.67  ? 338 ASP A N   1 
ATOM   1781 C  CA  . ASP A 1 257 ? 150.509 112.533 131.379 1.00 64.67  ? 338 ASP A CA  1 
ATOM   1782 C  C   . ASP A 1 257 ? 149.945 113.535 132.375 1.00 64.67  ? 338 ASP A C   1 
ATOM   1783 O  O   . ASP A 1 257 ? 149.443 113.137 133.430 1.00 64.67  ? 338 ASP A O   1 
ATOM   1784 C  CB  . ASP A 1 257 ? 152.037 112.517 131.474 1.00 64.67  ? 338 ASP A CB  1 
ATOM   1785 C  CG  . ASP A 1 257 ? 152.673 111.595 130.453 1.00 64.67  ? 338 ASP A CG  1 
ATOM   1786 O  OD1 . ASP A 1 257 ? 152.066 110.549 130.139 1.00 64.67  ? 338 ASP A OD1 1 
ATOM   1787 O  OD2 . ASP A 1 257 ? 153.778 111.913 129.967 1.00 64.67  ? 338 ASP A OD2 1 
ATOM   1788 N  N   . GLU A 1 258 ? 150.011 114.825 132.060 1.00 62.09  ? 339 GLU A N   1 
ATOM   1789 C  CA  . GLU A 1 258 ? 149.447 115.880 132.883 1.00 62.09  ? 339 GLU A CA  1 
ATOM   1790 C  C   . GLU A 1 258 ? 148.275 116.525 132.161 1.00 62.09  ? 339 GLU A C   1 
ATOM   1791 O  O   . GLU A 1 258 ? 148.298 116.669 130.934 1.00 62.09  ? 339 GLU A O   1 
ATOM   1792 C  CB  . GLU A 1 258 ? 150.500 116.947 133.215 1.00 62.09  ? 339 GLU A CB  1 
ATOM   1793 C  CG  . GLU A 1 258 ? 151.622 116.447 134.108 1.00 62.09  ? 339 GLU A CG  1 
ATOM   1794 C  CD  . GLU A 1 258 ? 152.603 117.541 134.480 1.00 62.09  ? 339 GLU A CD  1 
ATOM   1795 O  OE1 . GLU A 1 258 ? 152.473 118.664 133.950 1.00 62.09  ? 339 GLU A OE1 1 
ATOM   1796 O  OE2 . GLU A 1 258 ? 153.503 117.278 135.306 1.00 62.09  ? 339 GLU A OE2 1 
ATOM   1797 N  N   . PRO A 1 259 ? 147.238 116.920 132.894 1.00 58.64  ? 340 PRO A N   1 
ATOM   1798 C  CA  . PRO A 1 259 ? 146.057 117.500 132.249 1.00 58.64  ? 340 PRO A CA  1 
ATOM   1799 C  C   . PRO A 1 259 ? 146.326 118.900 131.717 1.00 58.64  ? 340 PRO A C   1 
ATOM   1800 O  O   . PRO A 1 259 ? 147.232 119.608 132.162 1.00 58.64  ? 340 PRO A O   1 
ATOM   1801 C  CB  . PRO A 1 259 ? 145.018 117.525 133.373 1.00 58.64  ? 340 PRO A CB  1 
ATOM   1802 C  CG  . PRO A 1 259 ? 145.824 117.614 134.617 1.00 58.64  ? 340 PRO A CG  1 
ATOM   1803 C  CD  . PRO A 1 259 ? 147.088 116.842 134.357 1.00 58.64  ? 340 PRO A CD  1 
ATOM   1804 N  N   . ILE A 1 260 ? 145.511 119.291 130.741 1.00 59.43  ? 341 ILE A N   1 
ATOM   1805 C  CA  . ILE A 1 260 ? 145.555 120.622 130.146 1.00 59.43  ? 341 ILE A CA  1 
ATOM   1806 C  C   . ILE A 1 260 ? 144.343 121.393 130.651 1.00 59.43  ? 341 ILE A C   1 
ATOM   1807 O  O   . ILE A 1 260 ? 143.201 120.946 130.483 1.00 59.43  ? 341 ILE A O   1 
ATOM   1808 C  CB  . ILE A 1 260 ? 145.573 120.560 128.612 1.00 59.43  ? 341 ILE A CB  1 
ATOM   1809 C  CG1 . ILE A 1 260 ? 146.815 119.812 128.125 1.00 59.43  ? 341 ILE A CG1 1 
ATOM   1810 C  CG2 . ILE A 1 260 ? 145.527 121.960 128.021 1.00 59.43  ? 341 ILE A CG2 1 
ATOM   1811 C  CD1 . ILE A 1 260 ? 146.820 119.538 126.637 1.00 59.43  ? 341 ILE A CD1 1 
ATOM   1812 N  N   . THR A 1 261 ? 144.588 122.545 131.267 1.00 57.04  ? 342 THR A N   1 
ATOM   1813 C  CA  . THR A 1 261 ? 143.550 123.327 131.918 1.00 57.04  ? 342 THR A CA  1 
ATOM   1814 C  C   . THR A 1 261 ? 143.234 124.581 131.113 1.00 57.04  ? 342 THR A C   1 
ATOM   1815 O  O   . THR A 1 261 ? 144.125 125.217 130.543 1.00 57.04  ? 342 THR A O   1 
ATOM   1816 C  CB  . THR A 1 261 ? 143.968 123.724 133.337 1.00 57.04  ? 342 THR A CB  1 
ATOM   1817 O  OG1 . THR A 1 261 ? 145.095 124.606 133.276 1.00 57.04  ? 342 THR A OG1 1 
ATOM   1818 C  CG2 . THR A 1 261 ? 144.342 122.490 134.145 1.00 57.04  ? 342 THR A CG2 1 
ATOM   1819 N  N   . GLY A 1 262 ? 141.957 124.926 131.074 1.00 51.42  ? 343 GLY A N   1 
ATOM   1820 C  CA  . GLY A 1 262 ? 141.517 126.118 130.379 1.00 51.42  ? 343 GLY A CA  1 
ATOM   1821 C  C   . GLY A 1 262 ? 140.035 126.050 130.083 1.00 51.42  ? 343 GLY A C   1 
ATOM   1822 O  O   . GLY A 1 262 ? 139.350 125.083 130.415 1.00 51.42  ? 343 GLY A O   1 
ATOM   1823 N  N   . GLY A 1 263 ? 139.555 127.108 129.449 1.00 50.43  ? 344 GLY A N   1 
ATOM   1824 C  CA  . GLY A 1 263 ? 138.166 127.164 129.022 1.00 50.43  ? 344 GLY A CA  1 
ATOM   1825 C  C   . GLY A 1 263 ? 137.246 127.712 130.092 1.00 50.43  ? 344 GLY A C   1 
ATOM   1826 O  O   . GLY A 1 263 ? 137.536 127.679 131.288 1.00 50.43  ? 344 GLY A O   1 
ATOM   1827 N  N   . SER A 1 264 ? 136.100 128.224 129.644 1.00 50.98  ? 345 SER A N   1 
ATOM   1828 C  CA  . SER A 1 264 ? 135.092 128.796 130.525 1.00 50.98  ? 345 SER A CA  1 
ATOM   1829 C  C   . SER A 1 264 ? 133.809 128.968 129.731 1.00 50.98  ? 345 SER A C   1 
ATOM   1830 O  O   . SER A 1 264 ? 133.866 129.177 128.514 1.00 50.98  ? 345 SER A O   1 
ATOM   1831 C  CB  . SER A 1 264 ? 135.555 130.146 131.095 1.00 50.98  ? 345 SER A CB  1 
ATOM   1832 O  OG  . SER A 1 264 ? 135.643 131.127 130.076 1.00 50.98  ? 345 SER A OG  1 
ATOM   1833 N  N   . PRO A 1 265 ? 132.636 128.887 130.380 1.00 52.28  ? 346 PRO A N   1 
ATOM   1834 C  CA  . PRO A 1 265 ? 132.454 128.597 131.804 1.00 52.28  ? 346 PRO A CA  1 
ATOM   1835 C  C   . PRO A 1 265 ? 132.133 127.132 132.099 1.00 52.28  ? 346 PRO A C   1 
ATOM   1836 O  O   . PRO A 1 265 ? 132.191 126.720 133.257 1.00 52.28  ? 346 PRO A O   1 
ATOM   1837 C  CB  . PRO A 1 265 ? 131.272 129.489 132.179 1.00 52.28  ? 346 PRO A CB  1 
ATOM   1838 C  CG  . PRO A 1 265 ? 130.448 129.550 130.921 1.00 52.28  ? 346 PRO A CG  1 
ATOM   1839 C  CD  . PRO A 1 265 ? 131.366 129.282 129.744 1.00 52.28  ? 346 PRO A CD  1 
ATOM   1840 N  N   . ASP A 1 266 ? 131.793 126.365 131.067 1.00 54.58  ? 347 ASP A N   1 
ATOM   1841 C  CA  . ASP A 1 266 ? 131.440 124.968 131.269 1.00 54.58  ? 347 ASP A CA  1 
ATOM   1842 C  C   . ASP A 1 266 ? 132.659 124.180 131.745 1.00 54.58  ? 347 ASP A C   1 
ATOM   1843 O  O   . ASP A 1 266 ? 133.757 124.344 131.202 1.00 54.58  ? 347 ASP A O   1 
ATOM   1844 C  CB  . ASP A 1 266 ? 130.895 124.360 129.978 1.00 54.58  ? 347 ASP A CB  1 
ATOM   1845 C  CG  . ASP A 1 266 ? 129.713 125.132 129.425 1.00 54.58  ? 347 ASP A CG  1 
ATOM   1846 O  OD1 . ASP A 1 266 ? 129.170 125.990 130.151 1.00 54.58  ? 347 ASP A OD1 1 
ATOM   1847 O  OD2 . ASP A 1 266 ? 129.326 124.879 128.264 1.00 54.58  ? 347 ASP A OD2 1 
ATOM   1848 N  N   . PRO A 1 267 ? 132.501 123.321 132.753 1.00 53.03  ? 348 PRO A N   1 
ATOM   1849 C  CA  . PRO A 1 267 ? 133.657 122.581 133.277 1.00 53.03  ? 348 PRO A CA  1 
ATOM   1850 C  C   . PRO A 1 267 ? 133.990 121.338 132.467 1.00 53.03  ? 348 PRO A C   1 
ATOM   1851 O  O   . PRO A 1 267 ? 135.153 120.929 132.405 1.00 53.03  ? 348 PRO A O   1 
ATOM   1852 C  CB  . PRO A 1 267 ? 133.217 122.226 134.700 1.00 53.03  ? 348 PRO A CB  1 
ATOM   1853 C  CG  . PRO A 1 267 ? 131.726 122.112 134.609 1.00 53.03  ? 348 PRO A CG  1 
ATOM   1854 C  CD  . PRO A 1 267 ? 131.258 122.998 133.476 1.00 53.03  ? 348 PRO A CD  1 
ATOM   1855 N  N   . GLY A 1 268 ? 132.988 120.732 131.843 1.00 53.52  ? 349 GLY A N   1 
ATOM   1856 C  CA  . GLY A 1 268 ? 133.216 119.535 131.054 1.00 53.52  ? 349 GLY A CA  1 
ATOM   1857 C  C   . GLY A 1 268 ? 131.900 118.971 130.566 1.00 53.52  ? 349 GLY A C   1 
ATOM   1858 O  O   . GLY A 1 268 ? 130.821 119.342 131.040 1.00 53.52  ? 349 GLY A O   1 
ATOM   1859 N  N   . VAL A 1 269 ? 132.009 118.059 129.603 1.00 53.87  ? 350 VAL A N   1 
ATOM   1860 C  CA  . VAL A 1 269 ? 130.850 117.358 129.059 1.00 53.87  ? 350 VAL A CA  1 
ATOM   1861 C  C   . VAL A 1 269 ? 131.247 115.913 128.791 1.00 53.87  ? 350 VAL A C   1 
ATOM   1862 O  O   . VAL A 1 269 ? 132.377 115.632 128.381 1.00 53.87  ? 350 VAL A O   1 
ATOM   1863 C  CB  . VAL A 1 269 ? 130.318 118.050 127.784 1.00 53.87  ? 350 VAL A CB  1 
ATOM   1864 C  CG1 . VAL A 1 269 ? 131.390 118.095 126.706 1.00 53.87  ? 350 VAL A CG1 1 
ATOM   1865 C  CG2 . VAL A 1 269 ? 129.061 117.357 127.275 1.00 53.87  ? 350 VAL A CG2 1 
ATOM   1866 N  N   . LYS A 1 270 ? 130.322 114.992 129.048 1.00 56.19  ? 351 LYS A N   1 
ATOM   1867 C  CA  . LYS A 1 270 ? 130.571 113.585 128.771 1.00 56.19  ? 351 LYS A CA  1 
ATOM   1868 C  C   . LYS A 1 270 ? 130.674 113.346 127.270 1.00 56.19  ? 351 LYS A C   1 
ATOM   1869 O  O   . LYS A 1 270 ? 129.909 113.906 126.480 1.00 56.19  ? 351 LYS A O   1 
ATOM   1870 C  CB  . LYS A 1 270 ? 129.459 112.721 129.365 1.00 56.19  ? 351 LYS A CB  1 
ATOM   1871 C  CG  . LYS A 1 270 ? 129.561 111.247 129.023 1.00 56.19  ? 351 LYS A CG  1 
ATOM   1872 C  CD  . LYS A 1 270 ? 128.378 110.476 129.572 1.00 56.19  ? 351 LYS A CD  1 
ATOM   1873 C  CE  . LYS A 1 270 ? 128.436 109.018 129.165 1.00 56.19  ? 351 LYS A CE  1 
ATOM   1874 N  NZ  . LYS A 1 270 ? 127.200 108.297 129.562 1.00 56.19  ? 351 LYS A NZ  1 
ATOM   1875 N  N   . GLY A 1 271 ? 131.625 112.512 126.880 1.00 55.31  ? 352 GLY A N   1 
ATOM   1876 C  CA  . GLY A 1 271 ? 131.836 112.170 125.484 1.00 55.31  ? 352 GLY A CA  1 
ATOM   1877 C  C   . GLY A 1 271 ? 132.320 110.745 125.348 1.00 55.31  ? 352 GLY A C   1 
ATOM   1878 O  O   . GLY A 1 271 ? 132.057 109.901 126.210 1.00 55.31  ? 352 GLY A O   1 
ATOM   1879 N  N   . PHE A 1 272 ? 133.034 110.476 124.258 1.00 53.64  ? 353 PHE A N   1 
ATOM   1880 C  CA  . PHE A 1 272 ? 133.550 109.143 123.982 1.00 53.64  ? 353 PHE A CA  1 
ATOM   1881 C  C   . PHE A 1 272 ? 134.668 109.254 122.957 1.00 53.64  ? 353 PHE A C   1 
ATOM   1882 O  O   . PHE A 1 272 ? 134.907 110.316 122.377 1.00 53.64  ? 353 PHE A O   1 
ATOM   1883 C  CB  . PHE A 1 272 ? 132.446 108.209 123.483 1.00 53.64  ? 353 PHE A CB  1 
ATOM   1884 C  CG  . PHE A 1 272 ? 131.852 108.634 122.181 1.00 53.64  ? 353 PHE A CG  1 
ATOM   1885 C  CD1 . PHE A 1 272 ? 130.766 109.487 122.157 1.00 53.64  ? 353 PHE A CD1 1 
ATOM   1886 C  CD2 . PHE A 1 272 ? 132.386 108.199 120.982 1.00 53.64  ? 353 PHE A CD2 1 
ATOM   1887 C  CE1 . PHE A 1 272 ? 130.218 109.892 120.965 1.00 53.64  ? 353 PHE A CE1 1 
ATOM   1888 C  CE2 . PHE A 1 272 ? 131.842 108.603 119.787 1.00 53.64  ? 353 PHE A CE2 1 
ATOM   1889 C  CZ  . PHE A 1 272 ? 130.759 109.452 119.781 1.00 53.64  ? 353 PHE A CZ  1 
ATOM   1890 N  N   . ALA A 1 273 ? 135.349 108.130 122.738 1.00 53.39  ? 354 ALA A N   1 
ATOM   1891 C  CA  . ALA A 1 273 ? 136.446 108.061 121.782 1.00 53.39  ? 354 ALA A CA  1 
ATOM   1892 C  C   . ALA A 1 273 ? 136.797 106.611 121.475 1.00 53.39  ? 354 ALA A C   1 
ATOM   1893 O  O   . ALA A 1 273 ? 137.045 105.821 122.391 1.00 53.39  ? 354 ALA A O   1 
ATOM   1894 C  CB  . ALA A 1 273 ? 137.672 108.803 122.316 1.00 53.39  ? 354 ALA A CB  1 
ATOM   1895 N  N   . PHE A 1 274 ? 136.823 106.252 120.195 1.00 50.19  ? 355 PHE A N   1 
ATOM   1896 C  CA  . PHE A 1 274 ? 137.201 104.912 119.769 1.00 50.19  ? 355 PHE A CA  1 
ATOM   1897 C  C   . PHE A 1 274 ? 138.671 104.920 119.379 1.00 50.19  ? 355 PHE A C   1 
ATOM   1898 O  O   . PHE A 1 274 ? 139.099 105.771 118.594 1.00 50.19  ? 355 PHE A O   1 
ATOM   1899 C  CB  . PHE A 1 274 ? 136.348 104.446 118.591 1.00 50.19  ? 355 PHE A CB  1 
ATOM   1900 C  CG  . PHE A 1 274 ? 134.900 104.273 118.926 1.00 50.19  ? 355 PHE A CG  1 
ATOM   1901 C  CD1 . PHE A 1 274 ? 134.461 103.144 119.589 1.00 50.19  ? 355 PHE A CD1 1 
ATOM   1902 C  CD2 . PHE A 1 274 ? 133.976 105.235 118.564 1.00 50.19  ? 355 PHE A CD2 1 
ATOM   1903 C  CE1 . PHE A 1 274 ? 133.128 102.985 119.898 1.00 50.19  ? 355 PHE A CE1 1 
ATOM   1904 C  CE2 . PHE A 1 274 ? 132.642 105.078 118.865 1.00 50.19  ? 355 PHE A CE2 1 
ATOM   1905 C  CZ  . PHE A 1 274 ? 132.217 103.950 119.528 1.00 50.19  ? 355 PHE A CZ  1 
ATOM   1906 N  N   . LEU A 1 275 ? 139.439 103.979 119.924 1.00 55.21  ? 356 LEU A N   1 
ATOM   1907 C  CA  . LEU A 1 275 ? 140.884 103.965 119.730 1.00 55.21  ? 356 LEU A CA  1 
ATOM   1908 C  C   . LEU A 1 275 ? 141.322 102.586 119.261 1.00 55.21  ? 356 LEU A C   1 
ATOM   1909 O  O   . LEU A 1 275 ? 141.320 101.632 120.045 1.00 55.21  ? 356 LEU A O   1 
ATOM   1910 C  CB  . LEU A 1 275 ? 141.619 104.351 121.021 1.00 55.21  ? 356 LEU A CB  1 
ATOM   1911 C  CG  . LEU A 1 275 ? 141.616 105.828 121.435 1.00 55.21  ? 356 LEU A CG  1 
ATOM   1912 C  CD1 . LEU A 1 275 ? 140.289 106.236 122.058 1.00 55.21  ? 356 LEU A CD1 1 
ATOM   1913 C  CD2 . LEU A 1 275 ? 142.761 106.142 122.385 1.00 55.21  ? 356 LEU A CD2 1 
ATOM   1914 N  N   . ASP A 1 276 ? 141.695 102.484 117.988 1.00 57.81  ? 357 ASP A N   1 
ATOM   1915 C  CA  . ASP A 1 276 ? 142.300 101.279 117.436 1.00 57.81  ? 357 ASP A CA  1 
ATOM   1916 C  C   . ASP A 1 276 ? 143.465 101.685 116.535 1.00 57.81  ? 357 ASP A C   1 
ATOM   1917 O  O   . ASP A 1 276 ? 143.542 101.302 115.365 1.00 57.81  ? 357 ASP A O   1 
ATOM   1918 C  CB  . ASP A 1 276 ? 141.270 100.440 116.680 1.00 57.81  ? 357 ASP A CB  1 
ATOM   1919 C  CG  . ASP A 1 276 ? 141.668 98.981  116.585 1.00 57.81  ? 357 ASP A CG  1 
ATOM   1920 O  OD1 . ASP A 1 276 ? 142.160 98.431  117.593 1.00 57.81  ? 357 ASP A OD1 1 
ATOM   1921 O  OD2 . ASP A 1 276 ? 141.497 98.386  115.501 1.00 57.81  ? 357 ASP A OD2 1 
ATOM   1922 N  N   . GLY A 1 277 ? 144.348 102.532 117.055 1.00 55.73  ? 358 GLY A N   1 
ATOM   1923 C  CA  . GLY A 1 277 ? 145.488 102.992 116.288 1.00 55.73  ? 358 GLY A CA  1 
ATOM   1924 C  C   . GLY A 1 277 ? 145.079 103.847 115.109 1.00 55.73  ? 358 GLY A C   1 
ATOM   1925 O  O   . GLY A 1 277 ? 144.640 104.987 115.282 1.00 55.73  ? 358 GLY A O   1 
ATOM   1926 N  N   . GLU A 1 278 ? 145.219 103.303 113.898 1.00 53.76  ? 359 GLU A N   1 
ATOM   1927 C  CA  . GLU A 1 278 ? 144.779 104.029 112.713 1.00 53.76  ? 359 GLU A CA  1 
ATOM   1928 C  C   . GLU A 1 278 ? 143.259 104.130 112.660 1.00 53.76  ? 359 GLU A C   1 
ATOM   1929 O  O   . GLU A 1 278 ? 142.713 105.022 112.001 1.00 53.76  ? 359 GLU A O   1 
ATOM   1930 C  CB  . GLU A 1 278 ? 145.319 103.357 111.450 1.00 53.76  ? 359 GLU A CB  1 
ATOM   1931 C  CG  . GLU A 1 278 ? 146.831 103.435 111.294 1.00 53.76  ? 359 GLU A CG  1 
ATOM   1932 C  CD  . GLU A 1 278 ? 147.562 102.363 112.080 1.00 53.76  ? 359 GLU A CD  1 
ATOM   1933 O  OE1 . GLU A 1 278 ? 146.889 101.514 112.702 1.00 53.76  ? 359 GLU A OE1 1 
ATOM   1934 O  OE2 . GLU A 1 278 ? 148.811 102.370 112.073 1.00 53.76  ? 359 GLU A OE2 1 
ATOM   1935 N  N   . ASN A 1 279 ? 142.557 103.226 113.345 1.00 55.03  ? 360 ASN A N   1 
ATOM   1936 C  CA  . ASN A 1 279 ? 141.094 103.252 113.368 1.00 55.03  ? 360 ASN A CA  1 
ATOM   1937 C  C   . ASN A 1 279 ? 140.649 103.964 114.644 1.00 55.03  ? 360 ASN A C   1 
ATOM   1938 O  O   . ASN A 1 279 ? 140.270 103.355 115.647 1.00 55.03  ? 360 ASN A O   1 
ATOM   1939 C  CB  . ASN A 1 279 ? 140.529 101.841 113.274 1.00 55.03  ? 360 ASN A CB  1 
ATOM   1940 C  CG  . ASN A 1 279 ? 139.016 101.823 113.217 1.00 55.03  ? 360 ASN A CG  1 
ATOM   1941 O  OD1 . ASN A 1 279 ? 138.385 102.807 112.832 1.00 55.03  ? 360 ASN A OD1 1 
ATOM   1942 N  ND2 . ASN A 1 279 ? 138.425 100.698 113.600 1.00 55.03  ? 360 ASN A ND2 1 
ATOM   1943 N  N   . SER A 1 280 ? 140.716 105.290 114.607 1.00 52.48  ? 361 SER A N   1 
ATOM   1944 C  CA  . SER A 1 280 ? 140.413 106.110 115.771 1.00 52.48  ? 361 SER A CA  1 
ATOM   1945 C  C   . SER A 1 280 ? 139.384 107.163 115.399 1.00 52.48  ? 361 SER A C   1 
ATOM   1946 O  O   . SER A 1 280 ? 139.415 107.704 114.290 1.00 52.48  ? 361 SER A O   1 
ATOM   1947 C  CB  . SER A 1 280 ? 141.679 106.769 116.320 1.00 52.48  ? 361 SER A CB  1 
ATOM   1948 O  OG  . SER A 1 280 ? 141.370 107.599 117.422 1.00 52.48  ? 361 SER A OG  1 
ATOM   1949 N  N   . TRP A 1 281 ? 138.473 107.443 116.326 1.00 49.22  ? 362 TRP A N   1 
ATOM   1950 C  CA  . TRP A 1 281 ? 137.412 108.420 116.127 1.00 49.22  ? 362 TRP A CA  1 
ATOM   1951 C  C   . TRP A 1 281 ? 137.197 109.202 117.413 1.00 49.22  ? 362 TRP A C   1 
ATOM   1952 O  O   . TRP A 1 281 ? 137.054 108.608 118.487 1.00 49.22  ? 362 TRP A O   1 
ATOM   1953 C  CB  . TRP A 1 281 ? 136.107 107.744 115.697 1.00 49.22  ? 362 TRP A CB  1 
ATOM   1954 C  CG  . TRP A 1 281 ? 136.033 107.465 114.231 1.00 49.22  ? 362 TRP A CG  1 
ATOM   1955 C  CD1 . TRP A 1 281 ? 136.283 106.279 113.608 1.00 49.22  ? 362 TRP A CD1 1 
ATOM   1956 C  CD2 . TRP A 1 281 ? 135.679 108.393 113.199 1.00 49.22  ? 362 TRP A CD2 1 
ATOM   1957 N  NE1 . TRP A 1 281 ? 136.112 106.411 112.252 1.00 49.22  ? 362 TRP A NE1 1 
ATOM   1958 C  CE2 . TRP A 1 281 ? 135.739 107.700 111.975 1.00 49.22  ? 362 TRP A CE2 1 
ATOM   1959 C  CE3 . TRP A 1 281 ? 135.318 109.744 113.192 1.00 49.22  ? 362 TRP A CE3 1 
ATOM   1960 C  CZ2 . TRP A 1 281 ? 135.451 108.311 110.757 1.00 49.22  ? 362 TRP A CZ2 1 
ATOM   1961 C  CZ3 . TRP A 1 281 ? 135.033 110.348 111.981 1.00 49.22  ? 362 TRP A CZ3 1 
ATOM   1962 C  CH2 . TRP A 1 281 ? 135.101 109.632 110.781 1.00 49.22  ? 362 TRP A CH2 1 
ATOM   1963 N  N   . LEU A 1 282 ? 137.172 110.529 117.298 1.00 48.65  ? 363 LEU A N   1 
ATOM   1964 C  CA  . LEU A 1 282 ? 136.914 111.418 118.423 1.00 48.65  ? 363 LEU A CA  1 
ATOM   1965 C  C   . LEU A 1 282 ? 135.749 112.333 118.079 1.00 48.65  ? 363 LEU A C   1 
ATOM   1966 O  O   . LEU A 1 282 ? 135.737 112.949 117.009 1.00 48.65  ? 363 LEU A O   1 
ATOM   1967 C  CB  . LEU A 1 282 ? 138.151 112.249 118.771 1.00 48.65  ? 363 LEU A CB  1 
ATOM   1968 C  CG  . LEU A 1 282 ? 139.515 111.570 118.650 1.00 48.65  ? 363 LEU A CG  1 
ATOM   1969 C  CD1 . LEU A 1 282 ? 140.626 112.578 118.878 1.00 48.65  ? 363 LEU A CD1 1 
ATOM   1970 C  CD2 . LEU A 1 282 ? 139.630 110.418 119.630 1.00 48.65  ? 363 LEU A CD2 1 
ATOM   1971 N  N   . GLY A 1 283 ? 134.781 112.425 118.986 1.00 49.43  ? 364 GLY A N   1 
ATOM   1972 C  CA  . GLY A 1 283 ? 133.595 113.244 118.791 1.00 49.43  ? 364 GLY A CA  1 
ATOM   1973 C  C   . GLY A 1 283 ? 133.549 114.373 119.809 1.00 49.43  ? 364 GLY A C   1 
ATOM   1974 O  O   . GLY A 1 283 ? 133.721 114.146 121.008 1.00 49.43  ? 364 GLY A O   1 
ATOM   1975 N  N   . ARG A 1 284 ? 133.314 115.586 119.311 1.00 51.67  ? 365 ARG A N   1 
ATOM   1976 C  CA  . ARG A 1 284 ? 133.343 116.773 120.156 1.00 51.67  ? 365 ARG A CA  1 
ATOM   1977 C  C   . ARG A 1 284 ? 132.372 117.819 119.629 1.00 51.67  ? 365 ARG A C   1 
ATOM   1978 O  O   . ARG A 1 284 ? 132.016 117.833 118.451 1.00 51.67  ? 365 ARG A O   1 
ATOM   1979 C  CB  . ARG A 1 284 ? 134.753 117.369 120.236 1.00 51.67  ? 365 ARG A CB  1 
ATOM   1980 C  CG  . ARG A 1 284 ? 135.284 117.865 118.904 1.00 51.67  ? 365 ARG A CG  1 
ATOM   1981 C  CD  . ARG A 1 284 ? 136.621 118.558 119.068 1.00 51.67  ? 365 ARG A CD  1 
ATOM   1982 N  NE  . ARG A 1 284 ? 136.858 119.541 118.019 1.00 51.67  ? 365 ARG A NE  1 
ATOM   1983 C  CZ  . ARG A 1 284 ? 137.969 120.254 117.900 1.00 51.67  ? 365 ARG A CZ  1 
ATOM   1984 N  NH1 . ARG A 1 284 ? 138.968 120.125 118.757 1.00 51.67  ? 365 ARG A NH1 1 
ATOM   1985 N  NH2 . ARG A 1 284 ? 138.081 121.119 116.896 1.00 51.67  ? 365 ARG A NH2 1 
ATOM   1986 N  N   . THR A 1 285 ? 131.963 118.716 120.522 1.00 53.72  ? 366 THR A N   1 
ATOM   1987 C  CA  . THR A 1 285 ? 131.058 119.792 120.147 1.00 53.72  ? 366 THR A CA  1 
ATOM   1988 C  C   . THR A 1 285 ? 131.768 120.819 119.271 1.00 53.72  ? 366 THR A C   1 
ATOM   1989 O  O   . THR A 1 285 ? 132.981 121.020 119.366 1.00 53.72  ? 366 THR A O   1 
ATOM   1990 C  CB  . THR A 1 285 ? 130.493 120.475 121.391 1.00 53.72  ? 366 THR A CB  1 
ATOM   1991 O  OG1 . THR A 1 285 ? 131.489 121.332 121.963 1.00 53.72  ? 366 THR A OG1 1 
ATOM   1992 C  CG2 . THR A 1 285 ? 130.067 119.438 122.419 1.00 53.72  ? 366 THR A CG2 1 
ATOM   1993 N  N   . ILE A 1 286 ? 130.989 121.470 118.402 1.00 54.17  ? 367 ILE A N   1 
ATOM   1994 C  CA  . ILE A 1 286 ? 131.549 122.472 117.497 1.00 54.17  ? 367 ILE A CA  1 
ATOM   1995 C  C   . ILE A 1 286 ? 132.123 123.642 118.286 1.00 54.17  ? 367 ILE A C   1 
ATOM   1996 O  O   . ILE A 1 286 ? 133.268 124.058 118.073 1.00 54.17  ? 367 ILE A O   1 
ATOM   1997 C  CB  . ILE A 1 286 ? 130.483 122.948 116.495 1.00 54.17  ? 367 ILE A CB  1 
ATOM   1998 C  CG1 . ILE A 1 286 ? 129.949 121.777 115.672 1.00 54.17  ? 367 ILE A CG1 1 
ATOM   1999 C  CG2 . ILE A 1 286 ? 131.056 124.019 115.581 1.00 54.17  ? 367 ILE A CG2 1 
ATOM   2000 C  CD1 . ILE A 1 286 ? 130.998 121.088 114.849 1.00 54.17  ? 367 ILE A CD1 1 
ATOM   2001 N  N   . SER A 1 287 ? 131.336 124.188 119.209 1.00 53.65  ? 368 SER A N   1 
ATOM   2002 C  CA  . SER A 1 287 ? 131.770 125.352 119.966 1.00 53.65  ? 368 SER A CA  1 
ATOM   2003 C  C   . SER A 1 287 ? 132.764 124.952 121.047 1.00 53.65  ? 368 SER A C   1 
ATOM   2004 O  O   . SER A 1 287 ? 132.666 123.874 121.638 1.00 53.65  ? 368 SER A O   1 
ATOM   2005 C  CB  . SER A 1 287 ? 130.568 126.056 120.593 1.00 53.65  ? 368 SER A CB  1 
ATOM   2006 O  OG  . SER A 1 287 ? 130.981 127.014 121.552 1.00 53.65  ? 368 SER A OG  1 
ATOM   2007 N  N   . LYS A 1 288 ? 133.728 125.832 121.303 1.00 53.62  ? 369 LYS A N   1 
ATOM   2008 C  CA  . LYS A 1 288 ? 134.735 125.610 122.328 1.00 53.62  ? 369 LYS A CA  1 
ATOM   2009 C  C   . LYS A 1 288 ? 134.291 126.085 123.705 1.00 53.62  ? 369 LYS A C   1 
ATOM   2010 O  O   . LYS A 1 288 ? 135.038 125.920 124.673 1.00 53.62  ? 369 LYS A O   1 
ATOM   2011 C  CB  . LYS A 1 288 ? 136.043 126.305 121.942 1.00 53.62  ? 369 LYS A CB  1 
ATOM   2012 C  CG  . LYS A 1 288 ? 136.050 127.793 122.233 1.00 53.62  ? 369 LYS A CG  1 
ATOM   2013 C  CD  . LYS A 1 288 ? 137.442 128.379 122.110 1.00 53.62  ? 369 LYS A CD  1 
ATOM   2014 C  CE  . LYS A 1 288 ? 137.464 129.830 122.563 1.00 53.62  ? 369 LYS A CE  1 
ATOM   2015 N  NZ  . LYS A 1 288 ? 138.825 130.425 122.459 1.00 53.62  ? 369 LYS A NZ  1 
ATOM   2016 N  N   . ASP A 1 289 ? 133.097 126.666 123.815 1.00 54.07  ? 370 ASP A N   1 
ATOM   2017 C  CA  . ASP A 1 289 ? 132.637 127.213 125.086 1.00 54.07  ? 370 ASP A CA  1 
ATOM   2018 C  C   . ASP A 1 289 ? 131.235 126.732 125.434 1.00 54.07  ? 370 ASP A C   1 
ATOM   2019 O  O   . ASP A 1 289 ? 130.862 126.692 126.611 1.00 54.07  ? 370 ASP A O   1 
ATOM   2020 C  CB  . ASP A 1 289 ? 132.672 128.742 125.047 1.00 54.07  ? 370 ASP A CB  1 
ATOM   2021 C  CG  . ASP A 1 289 ? 134.083 129.294 125.029 1.00 54.07  ? 370 ASP A CG  1 
ATOM   2022 O  OD1 . ASP A 1 289 ? 134.983 128.650 125.607 1.00 54.07  ? 370 ASP A OD1 1 
ATOM   2023 O  OD2 . ASP A 1 289 ? 134.293 130.373 124.436 1.00 54.07  ? 370 ASP A OD2 1 
ATOM   2024 N  N   . SER A 1 290 ? 130.449 126.365 124.425 1.00 54.03  ? 371 SER A N   1 
ATOM   2025 C  CA  . SER A 1 290 ? 129.063 125.975 124.624 1.00 54.03  ? 371 SER A CA  1 
ATOM   2026 C  C   . SER A 1 290 ? 128.803 124.625 123.972 1.00 54.03  ? 371 SER A C   1 
ATOM   2027 O  O   . SER A 1 290 ? 129.514 124.203 123.057 1.00 54.03  ? 371 SER A O   1 
ATOM   2028 C  CB  . SER A 1 290 ? 128.097 127.026 124.059 1.00 54.03  ? 371 SER A CB  1 
ATOM   2029 O  OG  . SER A 1 290 ? 128.214 127.119 122.650 1.00 54.03  ? 371 SER A OG  1 
ATOM   2030 N  N   . ARG A 1 291 ? 127.766 123.948 124.463 1.00 55.56  ? 372 ARG A N   1 
ATOM   2031 C  CA  . ARG A 1 291 ? 127.382 122.630 123.957 1.00 55.56  ? 372 ARG A CA  1 
ATOM   2032 C  C   . ARG A 1 291 ? 126.467 122.793 122.742 1.00 55.56  ? 372 ARG A C   1 
ATOM   2033 O  O   . ARG A 1 291 ? 125.267 122.516 122.775 1.00 55.56  ? 372 ARG A O   1 
ATOM   2034 C  CB  . ARG A 1 291 ? 126.709 121.817 125.055 1.00 55.56  ? 372 ARG A CB  1 
ATOM   2035 C  CG  . ARG A 1 291 ? 127.643 121.360 126.161 1.00 55.56  ? 372 ARG A CG  1 
ATOM   2036 C  CD  . ARG A 1 291 ? 126.915 121.307 127.494 1.00 55.56  ? 372 ARG A CD  1 
ATOM   2037 N  NE  . ARG A 1 291 ? 127.758 120.792 128.566 1.00 55.56  ? 372 ARG A NE  1 
ATOM   2038 C  CZ  . ARG A 1 291 ? 127.339 119.965 129.514 1.00 55.56  ? 372 ARG A CZ  1 
ATOM   2039 N  NH1 . ARG A 1 291 ? 126.088 119.537 129.554 1.00 55.56  ? 372 ARG A NH1 1 
ATOM   2040 N  NH2 . ARG A 1 291 ? 128.196 119.560 130.446 1.00 55.56  ? 372 ARG A NH2 1 
ATOM   2041 N  N   . SER A 1 292 ? 127.067 123.254 121.647 1.00 56.33  ? 373 SER A N   1 
ATOM   2042 C  CA  . SER A 1 292 ? 126.352 123.473 120.395 1.00 56.33  ? 373 SER A CA  1 
ATOM   2043 C  C   . SER A 1 292 ? 127.077 122.743 119.276 1.00 56.33  ? 373 SER A C   1 
ATOM   2044 O  O   . SER A 1 292 ? 128.271 122.970 119.057 1.00 56.33  ? 373 SER A O   1 
ATOM   2045 C  CB  . SER A 1 292 ? 126.238 124.966 120.077 1.00 56.33  ? 373 SER A CB  1 
ATOM   2046 O  OG  . SER A 1 292 ? 127.508 125.522 119.787 1.00 56.33  ? 373 SER A OG  1 
ATOM   2047 N  N   . GLY A 1 293 ? 126.359 121.874 118.572 1.00 55.26  ? 374 GLY A N   1 
ATOM   2048 C  CA  . GLY A 1 293 ? 126.917 121.154 117.448 1.00 55.26  ? 374 GLY A CA  1 
ATOM   2049 C  C   . GLY A 1 293 ? 127.678 119.911 117.869 1.00 55.26  ? 374 GLY A C   1 
ATOM   2050 O  O   . GLY A 1 293 ? 127.980 119.685 119.041 1.00 55.26  ? 374 GLY A O   1 
ATOM   2051 N  N   . TYR A 1 294 ? 127.991 119.079 116.875 1.00 52.98  ? 375 TYR A N   1 
ATOM   2052 C  CA  . TYR A 1 294 ? 128.761 117.867 117.121 1.00 52.98  ? 375 TYR A CA  1 
ATOM   2053 C  C   . TYR A 1 294 ? 129.463 117.433 115.843 1.00 52.98  ? 375 TYR A C   1 
ATOM   2054 O  O   . TYR A 1 294 ? 128.825 117.304 114.794 1.00 52.98  ? 375 TYR A O   1 
ATOM   2055 C  CB  . TYR A 1 294 ? 127.868 116.738 117.645 1.00 52.98  ? 375 TYR A CB  1 
ATOM   2056 C  CG  . TYR A 1 294 ? 128.630 115.723 118.461 1.00 52.98  ? 375 TYR A CG  1 
ATOM   2057 C  CD1 . TYR A 1 294 ? 128.819 115.903 119.823 1.00 52.98  ? 375 TYR A CD1 1 
ATOM   2058 C  CD2 . TYR A 1 294 ? 129.181 114.597 117.867 1.00 52.98  ? 375 TYR A CD2 1 
ATOM   2059 C  CE1 . TYR A 1 294 ? 129.523 114.987 120.572 1.00 52.98  ? 375 TYR A CE1 1 
ATOM   2060 C  CE2 . TYR A 1 294 ? 129.887 113.674 118.609 1.00 52.98  ? 375 TYR A CE2 1 
ATOM   2061 C  CZ  . TYR A 1 294 ? 130.055 113.874 119.961 1.00 52.98  ? 375 TYR A CZ  1 
ATOM   2062 O  OH  . TYR A 1 294 ? 130.759 112.959 120.707 1.00 52.98  ? 375 TYR A OH  1 
ATOM   2063 N  N   . GLU A 1 295 ? 130.769 117.192 115.950 1.00 53.22  ? 376 GLU A N   1 
ATOM   2064 C  CA  . GLU A 1 295 ? 131.613 116.775 114.842 1.00 53.22  ? 376 GLU A CA  1 
ATOM   2065 C  C   . GLU A 1 295 ? 132.465 115.598 115.292 1.00 53.22  ? 376 GLU A C   1 
ATOM   2066 O  O   . GLU A 1 295 ? 132.598 115.322 116.488 1.00 53.22  ? 376 GLU A O   1 
ATOM   2067 C  CB  . GLU A 1 295 ? 132.526 117.910 114.366 1.00 53.22  ? 376 GLU A CB  1 
ATOM   2068 C  CG  . GLU A 1 295 ? 133.776 118.073 115.224 1.00 53.22  ? 376 GLU A CG  1 
ATOM   2069 C  CD  . GLU A 1 295 ? 134.467 119.408 115.030 1.00 53.22  ? 376 GLU A CD  1 
ATOM   2070 O  OE1 . GLU A 1 295 ? 134.000 120.211 114.197 1.00 53.22  ? 376 GLU A OE1 1 
ATOM   2071 O  OE2 . GLU A 1 295 ? 135.482 119.656 115.716 1.00 53.22  ? 376 GLU A OE2 1 
ATOM   2072 N  N   . MET A 1 296 ? 133.045 114.902 114.316 1.00 50.24  ? 377 MET A N   1 
ATOM   2073 C  CA  . MET A 1 296 ? 133.984 113.824 114.583 1.00 50.24  ? 377 MET A CA  1 
ATOM   2074 C  C   . MET A 1 296 ? 135.209 113.915 113.689 1.00 50.24  ? 377 MET A C   1 
ATOM   2075 O  O   . MET A 1 296 ? 135.165 114.467 112.585 1.00 50.24  ? 377 MET A O   1 
ATOM   2076 C  CB  . MET A 1 296 ? 133.341 112.454 114.417 1.00 50.24  ? 377 MET A CB  1 
ATOM   2077 C  CG  . MET A 1 296 ? 132.315 112.169 115.470 1.00 50.24  ? 377 MET A CG  1 
ATOM   2078 S  SD  . MET A 1 296 ? 131.550 110.562 115.296 1.00 50.24  ? 377 MET A SD  1 
ATOM   2079 C  CE  . MET A 1 296 ? 130.400 110.691 116.645 1.00 50.24  ? 377 MET A CE  1 
ATOM   2080 N  N   . LEU A 1 297 ? 136.306 113.360 114.195 1.00 48.06  ? 378 LEU A N   1 
ATOM   2081 C  CA  . LEU A 1 297 ? 137.594 113.394 113.522 1.00 48.06  ? 378 LEU A CA  1 
ATOM   2082 C  C   . LEU A 1 297 ? 138.254 112.030 113.641 1.00 48.06  ? 378 LEU A C   1 
ATOM   2083 O  O   . LEU A 1 297 ? 138.228 111.417 114.712 1.00 48.06  ? 378 LEU A O   1 
ATOM   2084 C  CB  . LEU A 1 297 ? 138.496 114.478 114.124 1.00 48.06  ? 378 LEU A CB  1 
ATOM   2085 C  CG  . LEU A 1 297 ? 138.002 115.917 113.952 1.00 48.06  ? 378 LEU A CG  1 
ATOM   2086 C  CD1 . LEU A 1 297 ? 138.805 116.878 114.808 1.00 48.06  ? 378 LEU A CD1 1 
ATOM   2087 C  CD2 . LEU A 1 297 ? 138.052 116.326 112.492 1.00 48.06  ? 378 LEU A CD2 1 
ATOM   2088 N  N   . LYS A 1 298 ? 138.837 111.559 112.539 1.00 48.91  ? 379 LYS A N   1 
ATOM   2089 C  CA  . LYS A 1 298 ? 139.619 110.324 112.531 1.00 48.91  ? 379 LYS A CA  1 
ATOM   2090 C  C   . LYS A 1 298 ? 141.084 110.702 112.695 1.00 48.91  ? 379 LYS A C   1 
ATOM   2091 O  O   . LYS A 1 298 ? 141.847 110.765 111.729 1.00 48.91  ? 379 LYS A O   1 
ATOM   2092 C  CB  . LYS A 1 298 ? 139.381 109.529 111.252 1.00 48.91  ? 379 LYS A CB  1 
ATOM   2093 C  CG  . LYS A 1 298 ? 140.075 108.170 111.238 1.00 48.91  ? 379 LYS A CG  1 
ATOM   2094 C  CD  . LYS A 1 298 ? 139.873 107.427 109.927 1.00 48.91  ? 379 LYS A CD  1 
ATOM   2095 C  CE  . LYS A 1 298 ? 138.463 106.878 109.808 1.00 48.91  ? 379 LYS A CE  1 
ATOM   2096 N  NZ  . LYS A 1 298 ? 138.299 106.051 108.581 1.00 48.91  ? 379 LYS A NZ  1 
ATOM   2097 N  N   . VAL A 1 299 ? 141.480 110.966 113.931 1.00 51.87  ? 380 VAL A N   1 
ATOM   2098 C  CA  . VAL A 1 299 ? 142.867 111.337 114.215 1.00 51.87  ? 380 VAL A CA  1 
ATOM   2099 C  C   . VAL A 1 299 ? 143.692 110.062 114.367 1.00 51.87  ? 380 VAL A C   1 
ATOM   2100 O  O   . VAL A 1 299 ? 143.449 109.288 115.304 1.00 51.87  ? 380 VAL A O   1 
ATOM   2101 C  CB  . VAL A 1 299 ? 142.943 112.195 115.473 1.00 51.87  ? 380 VAL A CB  1 
ATOM   2102 C  CG1 . VAL A 1 299 ? 144.335 112.772 115.634 1.00 51.87  ? 380 VAL A CG1 1 
ATOM   2103 C  CG2 . VAL A 1 299 ? 141.903 113.305 115.419 1.00 51.87  ? 380 VAL A CG2 1 
ATOM   2104 N  N   . PRO A 1 300 ? 144.668 109.817 113.491 1.00 52.12  ? 381 PRO A N   1 
ATOM   2105 C  CA  . PRO A 1 300 ? 145.403 108.544 113.529 1.00 52.12  ? 381 PRO A CA  1 
ATOM   2106 C  C   . PRO A 1 300 ? 146.237 108.415 114.796 1.00 52.12  ? 381 PRO A C   1 
ATOM   2107 O  O   . PRO A 1 300 ? 146.882 109.371 115.233 1.00 52.12  ? 381 PRO A O   1 
ATOM   2108 C  CB  . PRO A 1 300 ? 146.288 108.610 112.280 1.00 52.12  ? 381 PRO A CB  1 
ATOM   2109 C  CG  . PRO A 1 300 ? 146.485 110.067 112.047 1.00 52.12  ? 381 PRO A CG  1 
ATOM   2110 C  CD  . PRO A 1 300 ? 145.199 110.731 112.466 1.00 52.12  ? 381 PRO A CD  1 
ATOM   2111 N  N   . ASN A 1 301 ? 146.215 107.216 115.382 1.00 56.52  ? 382 ASN A N   1 
ATOM   2112 C  CA  . ASN A 1 301 ? 146.960 106.896 116.599 1.00 56.52  ? 382 ASN A CA  1 
ATOM   2113 C  C   . ASN A 1 301 ? 146.593 107.848 117.739 1.00 56.52  ? 382 ASN A C   1 
ATOM   2114 O  O   . ASN A 1 301 ? 147.428 108.580 118.273 1.00 56.52  ? 382 ASN A O   1 
ATOM   2115 C  CB  . ASN A 1 301 ? 148.470 106.901 116.337 1.00 56.52  ? 382 ASN A CB  1 
ATOM   2116 C  CG  . ASN A 1 301 ? 148.855 106.055 115.142 1.00 56.52  ? 382 ASN A CG  1 
ATOM   2117 O  OD1 . ASN A 1 301 ? 148.243 105.021 114.876 1.00 56.52  ? 382 ASN A OD1 1 
ATOM   2118 N  ND2 . ASN A 1 301 ? 149.878 106.488 114.415 1.00 56.52  ? 382 ASN A ND2 1 
ATOM   2119 N  N   . ALA A 1 302 ? 145.311 107.822 118.108 1.00 58.94  ? 383 ALA A N   1 
ATOM   2120 C  CA  . ALA A 1 302 ? 144.847 108.605 119.245 1.00 58.94  ? 383 ALA A CA  1 
ATOM   2121 C  C   . ALA A 1 302 ? 145.390 108.091 120.570 1.00 58.94  ? 383 ALA A C   1 
ATOM   2122 O  O   . ALA A 1 302 ? 145.329 108.816 121.569 1.00 58.94  ? 383 ALA A O   1 
ATOM   2123 C  CB  . ALA A 1 302 ? 143.318 108.620 119.286 1.00 58.94  ? 383 ALA A CB  1 
ATOM   2124 N  N   . GLU A 1 303 ? 145.914 106.864 120.603 1.00 62.39  ? 384 GLU A N   1 
ATOM   2125 C  CA  . GLU A 1 303 ? 146.437 106.301 121.842 1.00 62.39  ? 384 GLU A CA  1 
ATOM   2126 C  C   . GLU A 1 303 ? 147.732 106.976 122.275 1.00 62.39  ? 384 GLU A C   1 
ATOM   2127 O  O   . GLU A 1 303 ? 147.887 107.325 123.451 1.00 62.39  ? 384 GLU A O   1 
ATOM   2128 C  CB  . GLU A 1 303 ? 146.666 104.796 121.682 1.00 62.39  ? 384 GLU A CB  1 
ATOM   2129 C  CG  . GLU A 1 303 ? 145.399 103.974 121.523 1.00 62.39  ? 384 GLU A CG  1 
ATOM   2130 C  CD  . GLU A 1 303 ? 145.680 102.493 121.362 1.00 62.39  ? 384 GLU A CD  1 
ATOM   2131 O  OE1 . GLU A 1 303 ? 146.868 102.117 121.284 1.00 62.39  ? 384 GLU A OE1 1 
ATOM   2132 O  OE2 . GLU A 1 303 ? 144.712 101.705 121.316 1.00 62.39  ? 384 GLU A OE2 1 
ATOM   2133 N  N   . THR A 1 304 ? 148.671 107.166 121.351 1.00 61.57  ? 385 THR A N   1 
ATOM   2134 C  CA  . THR A 1 304 ? 150.035 107.545 121.706 1.00 61.57  ? 385 THR A CA  1 
ATOM   2135 C  C   . THR A 1 304 ? 150.532 108.805 121.018 1.00 61.57  ? 385 THR A C   1 
ATOM   2136 O  O   . THR A 1 304 ? 151.344 109.531 121.597 1.00 61.57  ? 385 THR A O   1 
ATOM   2137 C  CB  . THR A 1 304 ? 151.001 106.393 121.387 1.00 61.57  ? 385 THR A CB  1 
ATOM   2138 O  OG1 . THR A 1 304 ? 150.972 106.119 119.981 1.00 61.57  ? 385 THR A OG1 1 
ATOM   2139 C  CG2 . THR A 1 304 ? 150.615 105.136 122.154 1.00 61.57  ? 385 THR A CG2 1 
ATOM   2140 N  N   . ASP A 1 305 ? 150.084 109.084 119.796 1.00 61.77  ? 386 ASP A N   1 
ATOM   2141 C  CA  . ASP A 1 305 ? 150.635 110.199 119.037 1.00 61.77  ? 386 ASP A CA  1 
ATOM   2142 C  C   . ASP A 1 305 ? 150.293 111.531 119.695 1.00 61.77  ? 386 ASP A C   1 
ATOM   2143 O  O   . ASP A 1 305 ? 149.136 111.803 120.027 1.00 61.77  ? 386 ASP A O   1 
ATOM   2144 C  CB  . ASP A 1 305 ? 150.112 110.175 117.602 1.00 61.77  ? 386 ASP A CB  1 
ATOM   2145 C  CG  . ASP A 1 305 ? 151.099 110.760 116.612 1.00 61.77  ? 386 ASP A CG  1 
ATOM   2146 O  OD1 . ASP A 1 305 ? 151.959 111.564 117.031 1.00 61.77  ? 386 ASP A OD1 1 
ATOM   2147 O  OD2 . ASP A 1 305 ? 151.015 110.418 115.414 1.00 61.77  ? 386 ASP A OD2 1 
ATOM   2148 N  N   . THR A 1 306 ? 151.316 112.366 119.880 1.00 60.53  ? 387 THR A N   1 
ATOM   2149 C  CA  . THR A 1 306 ? 151.141 113.677 120.493 1.00 60.53  ? 387 THR A CA  1 
ATOM   2150 C  C   . THR A 1 306 ? 151.016 114.792 119.461 1.00 60.53  ? 387 THR A C   1 
ATOM   2151 O  O   . THR A 1 306 ? 150.351 115.801 119.720 1.00 60.53  ? 387 THR A O   1 
ATOM   2152 C  CB  . THR A 1 306 ? 152.305 113.976 121.442 1.00 60.53  ? 387 THR A CB  1 
ATOM   2153 O  OG1 . THR A 1 306 ? 153.535 113.970 120.710 1.00 60.53  ? 387 THR A OG1 1 
ATOM   2154 C  CG2 . THR A 1 306 ? 152.372 112.932 122.547 1.00 60.53  ? 387 THR A CG2 1 
ATOM   2155 N  N   . GLN A 1 307 ? 151.641 114.633 118.294 1.00 60.93  ? 388 GLN A N   1 
ATOM   2156 C  CA  . GLN A 1 307 ? 151.531 115.596 117.208 1.00 60.93  ? 388 GLN A CA  1 
ATOM   2157 C  C   . GLN A 1 307 ? 150.488 115.190 116.174 1.00 60.93  ? 388 GLN A C   1 
ATOM   2158 O  O   . GLN A 1 307 ? 150.542 115.663 115.033 1.00 60.93  ? 388 GLN A O   1 
ATOM   2159 C  CB  . GLN A 1 307 ? 152.887 115.789 116.524 1.00 60.93  ? 388 GLN A CB  1 
ATOM   2160 C  CG  . GLN A 1 307 ? 153.949 116.453 117.384 1.00 60.93  ? 388 GLN A CG  1 
ATOM   2161 C  CD  . GLN A 1 307 ? 154.624 115.484 118.333 1.00 60.93  ? 388 GLN A CD  1 
ATOM   2162 O  OE1 . GLN A 1 307 ? 154.555 115.639 119.551 1.00 60.93  ? 388 GLN A OE1 1 
ATOM   2163 N  NE2 . GLN A 1 307 ? 155.280 114.473 117.776 1.00 60.93  ? 388 GLN A NE2 1 
ATOM   2164 N  N   . SER A 1 308 ? 149.549 114.327 116.546 1.00 58.82  ? 389 SER A N   1 
ATOM   2165 C  CA  . SER A 1 308 ? 148.599 113.787 115.585 1.00 58.82  ? 389 SER A CA  1 
ATOM   2166 C  C   . SER A 1 308 ? 147.621 114.856 115.117 1.00 58.82  ? 389 SER A C   1 
ATOM   2167 O  O   . SER A 1 308 ? 147.247 115.758 115.872 1.00 58.82  ? 389 SER A O   1 
ATOM   2168 C  CB  . SER A 1 308 ? 147.840 112.614 116.202 1.00 58.82  ? 389 SER A CB  1 
ATOM   2169 O  OG  . SER A 1 308 ? 147.136 113.019 117.363 1.00 58.82  ? 389 SER A OG  1 
ATOM   2170 N  N   . GLY A 1 309 ? 147.206 114.748 113.857 1.00 55.91  ? 390 GLY A N   1 
ATOM   2171 C  CA  . GLY A 1 309 ? 146.243 115.655 113.281 1.00 55.91  ? 390 GLY A CA  1 
ATOM   2172 C  C   . GLY A 1 309 ? 145.143 114.909 112.555 1.00 55.91  ? 390 GLY A C   1 
ATOM   2173 O  O   . GLY A 1 309 ? 145.364 113.839 111.981 1.00 55.91  ? 390 GLY A O   1 
ATOM   2174 N  N   . PRO A 1 310 ? 143.922 115.481 112.547 1.00 51.19  ? 391 PRO A N   1 
ATOM   2175 C  CA  . PRO A 1 310 ? 142.763 114.753 112.070 1.00 51.19  ? 391 PRO A CA  1 
ATOM   2176 C  C   . PRO A 1 310 ? 142.650 114.534 110.572 1.00 51.19  ? 391 PRO A C   1 
ATOM   2177 O  O   . PRO A 1 310 ? 143.160 115.342 109.819 1.00 51.19  ? 391 PRO A O   1 
ATOM   2178 C  CB  . PRO A 1 310 ? 141.576 115.666 112.379 1.00 51.19  ? 391 PRO A CB  1 
ATOM   2179 C  CG  . PRO A 1 310 ? 142.108 116.649 113.383 1.00 51.19  ? 391 PRO A CG  1 
ATOM   2180 C  CD  . PRO A 1 310 ? 143.552 116.831 112.980 1.00 51.19  ? 391 PRO A CD  1 
ATOM   2181 N  N   . THR A 1 311 ? 141.974 113.458 110.191 1.00 49.93  ? 392 THR A N   1 
ATOM   2182 C  CA  . THR A 1 311 ? 141.710 113.278 108.753 1.00 49.93  ? 392 THR A CA  1 
ATOM   2183 C  C   . THR A 1 311 ? 140.191 113.278 108.663 1.00 49.93  ? 392 THR A C   1 
ATOM   2184 O  O   . THR A 1 311 ? 139.588 114.204 109.181 1.00 49.93  ? 392 THR A O   1 
ATOM   2185 C  CB  . THR A 1 311 ? 142.588 112.156 108.201 1.00 49.93  ? 392 THR A CB  1 
ATOM   2186 O  OG1 . THR A 1 311 ? 142.607 112.293 106.782 1.00 49.93  ? 392 THR A OG1 1 
ATOM   2187 C  CG2 . THR A 1 311 ? 142.120 110.772 108.594 1.00 49.93  ? 392 THR A CG2 1 
ATOM   2188 N  N   . SER A 1 312 ? 139.586 112.250 108.153 1.00 48.01  ? 393 SER A N   1 
ATOM   2189 C  CA  . SER A 1 312 ? 138.126 112.294 107.926 1.00 48.01  ? 393 SER A CA  1 
ATOM   2190 C  C   . SER A 1 312 ? 137.287 113.122 108.906 1.00 48.01  ? 393 SER A C   1 
ATOM   2191 O  O   . SER A 1 312 ? 137.206 112.724 110.079 1.00 48.01  ? 393 SER A O   1 
ATOM   2192 C  CB  . SER A 1 312 ? 137.596 110.901 107.770 1.00 48.01  ? 393 SER A CB  1 
ATOM   2193 O  OG  . SER A 1 312 ? 138.313 110.208 106.761 1.00 48.01  ? 393 SER A OG  1 
ATOM   2194 N  N   . TYR A 1 313 ? 136.703 114.224 108.463 1.00 51.05  ? 394 TYR A N   1 
ATOM   2195 C  CA  . TYR A 1 313 ? 135.716 115.055 109.133 1.00 51.05  ? 394 TYR A CA  1 
ATOM   2196 C  C   . TYR A 1 313 ? 134.327 114.637 108.678 1.00 51.05  ? 394 TYR A C   1 
ATOM   2197 O  O   . TYR A 1 313 ? 134.126 114.242 107.527 1.00 51.05  ? 394 TYR A O   1 
ATOM   2198 C  CB  . TYR A 1 313 ? 135.962 116.554 108.841 1.00 51.05  ? 394 TYR A CB  1 
ATOM   2199 C  CG  . TYR A 1 313 ? 135.190 117.530 109.713 1.00 51.05  ? 394 TYR A CG  1 
ATOM   2200 C  CD1 . TYR A 1 313 ? 133.809 117.651 109.614 1.00 51.05  ? 394 TYR A CD1 1 
ATOM   2201 C  CD2 . TYR A 1 313 ? 135.846 118.328 110.640 1.00 51.05  ? 394 TYR A CD2 1 
ATOM   2202 C  CE1 . TYR A 1 313 ? 133.107 118.531 110.407 1.00 51.05  ? 394 TYR A CE1 1 
ATOM   2203 C  CE2 . TYR A 1 313 ? 135.150 119.214 111.439 1.00 51.05  ? 394 TYR A CE2 1 
ATOM   2204 C  CZ  . TYR A 1 313 ? 133.780 119.311 111.316 1.00 51.05  ? 394 TYR A CZ  1 
ATOM   2205 O  OH  . TYR A 1 313 ? 133.076 120.190 112.106 1.00 51.05  ? 394 TYR A OH  1 
ATOM   2206 N  N   . GLN A 1 314 ? 133.372 114.706 109.600 1.00 50.02  ? 395 GLN A N   1 
ATOM   2207 C  CA  . GLN A 1 314 ? 131.970 114.510 109.267 1.00 50.02  ? 395 GLN A CA  1 
ATOM   2208 C  C   . GLN A 1 314 ? 131.131 115.372 110.196 1.00 50.02  ? 395 GLN A C   1 
ATOM   2209 O  O   . GLN A 1 314 ? 131.243 115.256 111.420 1.00 50.02  ? 395 GLN A O   1 
ATOM   2210 C  CB  . GLN A 1 314 ? 131.567 113.036 109.384 1.00 50.02  ? 395 GLN A CB  1 
ATOM   2211 C  CG  . GLN A 1 314 ? 130.149 112.750 108.924 1.00 50.02  ? 395 GLN A CG  1 
ATOM   2212 C  CD  . GLN A 1 314 ? 129.832 111.270 108.896 1.00 50.02  ? 395 GLN A CD  1 
ATOM   2213 O  OE1 . GLN A 1 314 ? 130.730 110.434 108.792 1.00 50.02  ? 395 GLN A OE1 1 
ATOM   2214 N  NE2 . GLN A 1 314 ? 128.550 110.937 108.987 1.00 50.02  ? 395 GLN A NE2 1 
ATOM   2215 N  N   . LEU A 1 315 ? 130.298 116.231 109.614 1.00 52.17  ? 396 LEU A N   1 
ATOM   2216 C  CA  . LEU A 1 315 ? 129.463 117.149 110.382 1.00 52.17  ? 396 LEU A CA  1 
ATOM   2217 C  C   . LEU A 1 315 ? 128.180 116.427 110.773 1.00 52.17  ? 396 LEU A C   1 
ATOM   2218 O  O   . LEU A 1 315 ? 127.288 116.235 109.941 1.00 52.17  ? 396 LEU A O   1 
ATOM   2219 C  CB  . LEU A 1 315 ? 129.160 118.408 109.575 1.00 52.17  ? 396 LEU A CB  1 
ATOM   2220 C  CG  . LEU A 1 315 ? 128.568 119.584 110.354 1.00 52.17  ? 396 LEU A CG  1 
ATOM   2221 C  CD1 . LEU A 1 315 ? 129.612 120.200 111.271 1.00 52.17  ? 396 LEU A CD1 1 
ATOM   2222 C  CD2 . LEU A 1 315 ? 127.998 120.625 109.405 1.00 52.17  ? 396 LEU A CD2 1 
ATOM   2223 N  N   . ILE A 1 316 ? 128.087 116.034 112.038 1.00 50.82  ? 397 ILE A N   1 
ATOM   2224 C  CA  . ILE A 1 316 ? 126.934 115.306 112.551 1.00 50.82  ? 397 ILE A CA  1 
ATOM   2225 C  C   . ILE A 1 316 ? 125.806 116.250 112.940 1.00 50.82  ? 397 ILE A C   1 
ATOM   2226 O  O   . ILE A 1 316 ? 124.668 116.083 112.501 1.00 50.82  ? 397 ILE A O   1 
ATOM   2227 C  CB  . ILE A 1 316 ? 127.352 114.414 113.741 1.00 50.82  ? 397 ILE A CB  1 
ATOM   2228 C  CG1 . ILE A 1 316 ? 128.429 113.420 113.307 1.00 50.82  ? 397 ILE A CG1 1 
ATOM   2229 C  CG2 . ILE A 1 316 ? 126.146 113.688 114.313 1.00 50.82  ? 397 ILE A CG2 1 
ATOM   2230 C  CD1 . ILE A 1 316 ? 127.980 112.474 112.216 1.00 50.82  ? 397 ILE A CD1 1 
ATOM   2231 N  N   . VAL A 1 317 ? 126.101 117.249 113.767 1.00 54.39  ? 398 VAL A N   1 
ATOM   2232 C  CA  . VAL A 1 317 ? 125.110 118.217 114.220 1.00 54.39  ? 398 VAL A CA  1 
ATOM   2233 C  C   . VAL A 1 317 ? 125.657 119.613 113.964 1.00 54.39  ? 398 VAL A C   1 
ATOM   2234 O  O   . VAL A 1 317 ? 126.775 119.932 114.382 1.00 54.39  ? 398 VAL A O   1 
ATOM   2235 C  CB  . VAL A 1 317 ? 124.767 118.024 115.710 1.00 54.39  ? 398 VAL A CB  1 
ATOM   2236 C  CG1 . VAL A 1 317 ? 124.116 119.269 116.274 1.00 54.39  ? 398 VAL A CG1 1 
ATOM   2237 C  CG2 . VAL A 1 317 ? 123.861 116.818 115.891 1.00 54.39  ? 398 VAL A CG2 1 
ATOM   2238 N  N   . ASN A 1 318 ? 124.872 120.441 113.278 1.00 57.92  ? 399 ASN A N   1 
ATOM   2239 C  CA  . ASN A 1 318 ? 125.316 121.781 112.929 1.00 57.92  ? 399 ASN A CA  1 
ATOM   2240 C  C   . ASN A 1 318 ? 125.376 122.671 114.170 1.00 57.92  ? 399 ASN A C   1 
ATOM   2241 O  O   . ASN A 1 318 ? 124.807 122.368 115.222 1.00 57.92  ? 399 ASN A O   1 
ATOM   2242 C  CB  . ASN A 1 318 ? 124.398 122.391 111.869 1.00 57.92  ? 399 ASN A CB  1 
ATOM   2243 C  CG  . ASN A 1 318 ? 122.931 122.212 112.194 1.00 57.92  ? 399 ASN A CG  1 
ATOM   2244 O  OD1 . ASN A 1 318 ? 122.576 121.663 113.234 1.00 57.92  ? 399 ASN A OD1 1 
ATOM   2245 N  ND2 . ASN A 1 318 ? 122.067 122.678 111.300 1.00 57.92  ? 399 ASN A ND2 1 
ATOM   2246 N  N   . ASN A 1 319 ? 126.089 123.789 114.030 1.00 58.18  ? 400 ASN A N   1 
ATOM   2247 C  CA  . ASN A 1 319 ? 126.343 124.693 115.145 1.00 58.18  ? 400 ASN A CA  1 
ATOM   2248 C  C   . ASN A 1 319 ? 125.079 125.394 115.634 1.00 58.18  ? 400 ASN A C   1 
ATOM   2249 O  O   . ASN A 1 319 ? 125.061 125.885 116.767 1.00 58.18  ? 400 ASN A O   1 
ATOM   2250 C  CB  . ASN A 1 319 ? 127.395 125.724 114.720 1.00 58.18  ? 400 ASN A CB  1 
ATOM   2251 C  CG  . ASN A 1 319 ? 127.977 126.502 115.889 1.00 58.18  ? 400 ASN A CG  1 
ATOM   2252 O  OD1 . ASN A 1 319 ? 127.620 126.285 117.045 1.00 58.18  ? 400 ASN A OD1 1 
ATOM   2253 N  ND2 . ASN A 1 319 ? 128.888 127.419 115.585 1.00 58.18  ? 400 ASN A ND2 1 
ATOM   2254 N  N   . GLN A 1 320 ? 124.020 125.436 114.824 1.00 61.54  ? 401 GLN A N   1 
ATOM   2255 C  CA  . GLN A 1 320 ? 122.836 126.210 115.184 1.00 61.54  ? 401 GLN A CA  1 
ATOM   2256 C  C   . GLN A 1 320 ? 122.102 125.647 116.395 1.00 61.54  ? 401 GLN A C   1 
ATOM   2257 O  O   . GLN A 1 320 ? 121.732 126.411 117.294 1.00 61.54  ? 401 GLN A O   1 
ATOM   2258 C  CB  . GLN A 1 320 ? 121.879 126.287 113.995 1.00 61.54  ? 401 GLN A CB  1 
ATOM   2259 C  CG  . GLN A 1 320 ? 120.928 127.471 114.046 1.00 61.54  ? 401 GLN A CG  1 
ATOM   2260 C  CD  . GLN A 1 320 ? 120.157 127.657 112.754 1.00 61.54  ? 401 GLN A CD  1 
ATOM   2261 O  OE1 . GLN A 1 320 ? 120.376 126.941 111.777 1.00 61.54  ? 401 GLN A OE1 1 
ATOM   2262 N  NE2 . GLN A 1 320 ? 119.247 128.624 112.744 1.00 61.54  ? 401 GLN A NE2 1 
ATOM   2263 N  N   . ASN A 1 321 ? 121.883 124.337 116.448 1.00 57.38  ? 402 ASN A N   1 
ATOM   2264 C  CA  . ASN A 1 321 ? 121.091 123.727 117.506 1.00 57.38  ? 402 ASN A CA  1 
ATOM   2265 C  C   . ASN A 1 321 ? 122.000 123.182 118.601 1.00 57.38  ? 402 ASN A C   1 
ATOM   2266 O  O   . ASN A 1 321 ? 123.221 123.093 118.447 1.00 57.38  ? 402 ASN A O   1 
ATOM   2267 C  CB  . ASN A 1 321 ? 120.187 122.618 116.953 1.00 57.38  ? 402 ASN A CB  1 
ATOM   2268 C  CG  . ASN A 1 321 ? 120.936 121.641 116.081 1.00 57.38  ? 402 ASN A CG  1 
ATOM   2269 O  OD1 . ASN A 1 321 ? 122.153 121.727 115.944 1.00 57.38  ? 402 ASN A OD1 1 
ATOM   2270 N  ND2 . ASN A 1 321 ? 120.212 120.704 115.482 1.00 57.38  ? 402 ASN A ND2 1 
ATOM   2271 N  N   . TRP A 1 322 ? 121.382 122.816 119.719 1.00 59.97  ? 403 TRP A N   1 
ATOM   2272 C  CA  . TRP A 1 322 ? 122.119 122.424 120.908 1.00 59.97  ? 403 TRP A CA  1 
ATOM   2273 C  C   . TRP A 1 322 ? 122.390 120.922 120.918 1.00 59.97  ? 403 TRP A C   1 
ATOM   2274 O  O   . TRP A 1 322 ? 121.661 120.123 120.324 1.00 59.97  ? 403 TRP A O   1 
ATOM   2275 C  CB  . TRP A 1 322 ? 121.350 122.817 122.170 1.00 59.97  ? 403 TRP A CB  1 
ATOM   2276 C  CG  . TRP A 1 322 ? 121.154 124.292 122.322 1.00 59.97  ? 403 TRP A CG  1 
ATOM   2277 C  CD1 . TRP A 1 322 ? 119.972 124.970 122.267 1.00 59.97  ? 403 TRP A CD1 1 
ATOM   2278 C  CD2 . TRP A 1 322 ? 122.169 125.275 122.556 1.00 59.97  ? 403 TRP A CD2 1 
ATOM   2279 N  NE1 . TRP A 1 322 ? 120.187 126.313 122.451 1.00 59.97  ? 403 TRP A NE1 1 
ATOM   2280 C  CE2 . TRP A 1 322 ? 121.528 126.526 122.631 1.00 59.97  ? 403 TRP A CE2 1 
ATOM   2281 C  CE3 . TRP A 1 322 ? 123.557 125.218 122.709 1.00 59.97  ? 403 TRP A CE3 1 
ATOM   2282 C  CZ2 . TRP A 1 322 ? 122.227 127.711 122.852 1.00 59.97  ? 403 TRP A CZ2 1 
ATOM   2283 C  CZ3 . TRP A 1 322 ? 124.250 126.395 122.929 1.00 59.97  ? 403 TRP A CZ3 1 
ATOM   2284 C  CH2 . TRP A 1 322 ? 123.584 127.624 122.998 1.00 59.97  ? 403 TRP A CH2 1 
ATOM   2285 N  N   . SER A 1 323 ? 123.459 120.549 121.610 1.00 57.51  ? 404 SER A N   1 
ATOM   2286 C  CA  . SER A 1 323 ? 123.852 119.162 121.807 1.00 57.51  ? 404 SER A CA  1 
ATOM   2287 C  C   . SER A 1 323 ? 123.871 118.859 123.305 1.00 57.51  ? 404 SER A C   1 
ATOM   2288 O  O   . SER A 1 323 ? 123.454 119.675 124.131 1.00 57.51  ? 404 SER A O   1 
ATOM   2289 C  CB  . SER A 1 323 ? 125.209 118.891 121.153 1.00 57.51  ? 404 SER A CB  1 
ATOM   2290 O  OG  . SER A 1 323 ? 126.224 119.684 121.740 1.00 57.51  ? 404 SER A OG  1 
ATOM   2291 N  N   . GLY A 1 324 ? 124.358 117.672 123.652 1.00 59.37  ? 405 GLY A N   1 
ATOM   2292 C  CA  . GLY A 1 324 ? 124.426 117.270 125.042 1.00 59.37  ? 405 GLY A CA  1 
ATOM   2293 C  C   . GLY A 1 324 ? 125.397 116.134 125.284 1.00 59.37  ? 405 GLY A C   1 
ATOM   2294 O  O   . GLY A 1 324 ? 126.468 116.085 124.670 1.00 59.37  ? 405 GLY A O   1 
ATOM   2295 N  N   . TYR A 1 325 ? 125.039 115.217 126.178 1.00 59.65  ? 406 TYR A N   1 
ATOM   2296 C  CA  . TYR A 1 325 ? 125.898 114.083 126.478 1.00 59.65  ? 406 TYR A CA  1 
ATOM   2297 C  C   . TYR A 1 325 ? 125.967 113.137 125.288 1.00 59.65  ? 406 TYR A C   1 
ATOM   2298 O  O   . TYR A 1 325 ? 124.944 112.783 124.696 1.00 59.65  ? 406 TYR A O   1 
ATOM   2299 C  CB  . TYR A 1 325 ? 125.393 113.337 127.712 1.00 59.65  ? 406 TYR A CB  1 
ATOM   2300 C  CG  . TYR A 1 325 ? 125.747 114.009 129.019 1.00 59.65  ? 406 TYR A CG  1 
ATOM   2301 C  CD1 . TYR A 1 325 ? 126.790 114.921 129.090 1.00 59.65  ? 406 TYR A CD1 1 
ATOM   2302 C  CD2 . TYR A 1 325 ? 125.049 113.720 130.182 1.00 59.65  ? 406 TYR A CD2 1 
ATOM   2303 C  CE1 . TYR A 1 325 ? 127.122 115.535 130.281 1.00 59.65  ? 406 TYR A CE1 1 
ATOM   2304 C  CE2 . TYR A 1 325 ? 125.375 114.327 131.378 1.00 59.65  ? 406 TYR A CE2 1 
ATOM   2305 C  CZ  . TYR A 1 325 ? 126.412 115.235 131.421 1.00 59.65  ? 406 TYR A CZ  1 
ATOM   2306 O  OH  . TYR A 1 325 ? 126.740 115.844 132.610 1.00 59.65  ? 406 TYR A OH  1 
ATOM   2307 N  N   . SER A 1 326 ? 127.184 112.728 124.941 1.00 56.70  ? 407 SER A N   1 
ATOM   2308 C  CA  . SER A 1 326 ? 127.426 111.814 123.835 1.00 56.70  ? 407 SER A CA  1 
ATOM   2309 C  C   . SER A 1 326 ? 128.083 110.548 124.361 1.00 56.70  ? 407 SER A C   1 
ATOM   2310 O  O   . SER A 1 326 ? 128.999 110.610 125.187 1.00 56.70  ? 407 SER A O   1 
ATOM   2311 C  CB  . SER A 1 326 ? 128.311 112.458 122.767 1.00 56.70  ? 407 SER A CB  1 
ATOM   2312 O  OG  . SER A 1 326 ? 129.452 113.062 123.350 1.00 56.70  ? 407 SER A OG  1 
ATOM   2313 N  N   . GLY A 1 327 ? 127.612 109.396 123.877 1.00 58.80  ? 408 GLY A N   1 
ATOM   2314 C  CA  . GLY A 1 327 ? 128.099 108.120 124.349 1.00 58.80  ? 408 GLY A CA  1 
ATOM   2315 C  C   . GLY A 1 327 ? 128.378 107.163 123.203 1.00 58.80  ? 408 GLY A C   1 
ATOM   2316 O  O   . GLY A 1 327 ? 128.008 107.404 122.051 1.00 58.80  ? 408 GLY A O   1 
ATOM   2317 N  N   . ALA A 1 328 ? 129.031 106.058 123.554 1.00 55.25  ? 409 ALA A N   1 
ATOM   2318 C  CA  . ALA A 1 328 ? 129.457 105.043 122.602 1.00 55.25  ? 409 ALA A CA  1 
ATOM   2319 C  C   . ALA A 1 328 ? 128.897 103.687 123.002 1.00 55.25  ? 409 ALA A C   1 
ATOM   2320 O  O   . ALA A 1 328 ? 128.862 103.347 124.189 1.00 55.25  ? 409 ALA A O   1 
ATOM   2321 C  CB  . ALA A 1 328 ? 130.983 104.973 122.530 1.00 55.25  ? 409 ALA A CB  1 
ATOM   2322 N  N   . PHE A 1 329 ? 128.458 102.913 122.011 1.00 58.16  ? 410 PHE A N   1 
ATOM   2323 C  CA  . PHE A 1 329 ? 127.971 101.565 122.262 1.00 58.16  ? 410 PHE A CA  1 
ATOM   2324 C  C   . PHE A 1 329 ? 128.267 100.686 121.056 1.00 58.16  ? 410 PHE A C   1 
ATOM   2325 O  O   . PHE A 1 329 ? 128.339 101.161 119.922 1.00 58.16  ? 410 PHE A O   1 
ATOM   2326 C  CB  . PHE A 1 329 ? 126.472 101.554 122.591 1.00 58.16  ? 410 PHE A CB  1 
ATOM   2327 C  CG  . PHE A 1 329 ? 125.581 101.600 121.386 1.00 58.16  ? 410 PHE A CG  1 
ATOM   2328 C  CD1 . PHE A 1 329 ? 125.489 102.748 120.621 1.00 58.16  ? 410 PHE A CD1 1 
ATOM   2329 C  CD2 . PHE A 1 329 ? 124.832 100.495 121.019 1.00 58.16  ? 410 PHE A CD2 1 
ATOM   2330 C  CE1 . PHE A 1 329 ? 124.665 102.796 119.516 1.00 58.16  ? 410 PHE A CE1 1 
ATOM   2331 C  CE2 . PHE A 1 329 ? 124.009 100.536 119.912 1.00 58.16  ? 410 PHE A CE2 1 
ATOM   2332 C  CZ  . PHE A 1 329 ? 123.926 101.688 119.159 1.00 58.16  ? 410 PHE A CZ  1 
ATOM   2333 N  N   . ILE A 1 330 ? 128.450 99.395  121.315 1.00 58.63  ? 411 ILE A N   1 
ATOM   2334 C  CA  . ILE A 1 330 ? 128.797 98.431  120.279 1.00 58.63  ? 411 ILE A CA  1 
ATOM   2335 C  C   . ILE A 1 330 ? 127.861 97.237  120.391 1.00 58.63  ? 411 ILE A C   1 
ATOM   2336 O  O   . ILE A 1 330 ? 127.633 96.724  121.491 1.00 58.63  ? 411 ILE A O   1 
ATOM   2337 C  CB  . ILE A 1 330 ? 130.264 97.976  120.387 1.00 58.63  ? 411 ILE A CB  1 
ATOM   2338 C  CG1 . ILE A 1 330 ? 131.196 99.178  120.543 1.00 58.63  ? 411 ILE A CG1 1 
ATOM   2339 C  CG2 . ILE A 1 330 ? 130.649 97.169  119.173 1.00 58.63  ? 411 ILE A CG2 1 
ATOM   2340 C  CD1 . ILE A 1 330 ? 132.661 98.823  120.471 1.00 58.63  ? 411 ILE A CD1 1 
ATOM   2341 N  N   . ASP A 1 331 ? 127.323 96.797  119.253 1.00 61.56  ? 412 ASP A N   1 
ATOM   2342 C  CA  . ASP A 1 331 ? 126.485 95.599  119.201 1.00 61.56  ? 412 ASP A CA  1 
ATOM   2343 C  C   . ASP A 1 331 ? 127.399 94.397  118.983 1.00 61.56  ? 412 ASP A C   1 
ATOM   2344 O  O   . ASP A 1 331 ? 127.670 93.965  117.860 1.00 61.56  ? 412 ASP A O   1 
ATOM   2345 C  CB  . ASP A 1 331 ? 125.432 95.720  118.107 1.00 61.56  ? 412 ASP A CB  1 
ATOM   2346 C  CG  . ASP A 1 331 ? 124.190 94.902  118.403 1.00 61.56  ? 412 ASP A CG  1 
ATOM   2347 O  OD1 . ASP A 1 331 ? 124.131 94.276  119.482 1.00 61.56  ? 412 ASP A OD1 1 
ATOM   2348 O  OD2 . ASP A 1 331 ? 123.270 94.887  117.559 1.00 61.56  ? 412 ASP A OD2 1 
ATOM   2349 N  N   . TYR A 1 332 ? 127.887 93.851  120.100 1.00 57.70  ? 413 TYR A N   1 
ATOM   2350 C  CA  . TYR A 1 332 ? 128.859 92.765  120.040 1.00 57.70  ? 413 TYR A CA  1 
ATOM   2351 C  C   . TYR A 1 332 ? 128.251 91.485  119.482 1.00 57.70  ? 413 TYR A C   1 
ATOM   2352 O  O   . TYR A 1 332 ? 128.985 90.605  119.017 1.00 57.70  ? 413 TYR A O   1 
ATOM   2353 C  CB  . TYR A 1 332 ? 129.437 92.510  121.431 1.00 57.70  ? 413 TYR A CB  1 
ATOM   2354 C  CG  . TYR A 1 332 ? 130.145 93.703  122.030 1.00 57.70  ? 413 TYR A CG  1 
ATOM   2355 C  CD1 . TYR A 1 332 ? 131.354 94.149  121.517 1.00 57.70  ? 413 TYR A CD1 1 
ATOM   2356 C  CD2 . TYR A 1 332 ? 129.602 94.385  123.109 1.00 57.70  ? 413 TYR A CD2 1 
ATOM   2357 C  CE1 . TYR A 1 332 ? 132.003 95.238  122.063 1.00 57.70  ? 413 TYR A CE1 1 
ATOM   2358 C  CE2 . TYR A 1 332 ? 130.244 95.476  123.660 1.00 57.70  ? 413 TYR A CE2 1 
ATOM   2359 C  CZ  . TYR A 1 332 ? 131.444 95.898  123.133 1.00 57.70  ? 413 TYR A CZ  1 
ATOM   2360 O  OH  . TYR A 1 332 ? 132.087 96.983  123.680 1.00 57.70  ? 413 TYR A OH  1 
ATOM   2361 N  N   . TRP A 1 333 ? 126.923 91.360  119.514 1.00 62.27  ? 414 TRP A N   1 
ATOM   2362 C  CA  . TRP A 1 333 ? 126.236 90.150  119.081 1.00 62.27  ? 414 TRP A CA  1 
ATOM   2363 C  C   . TRP A 1 333 ? 125.872 90.173  117.601 1.00 62.27  ? 414 TRP A C   1 
ATOM   2364 O  O   . TRP A 1 333 ? 124.954 89.456  117.181 1.00 62.27  ? 414 TRP A O   1 
ATOM   2365 C  CB  . TRP A 1 333 ? 124.985 89.930  119.932 1.00 62.27  ? 414 TRP A CB  1 
ATOM   2366 C  CG  . TRP A 1 333 ? 125.274 89.349  121.279 1.00 62.27  ? 414 TRP A CG  1 
ATOM   2367 C  CD1 . TRP A 1 333 ? 125.540 88.044  121.568 1.00 62.27  ? 414 TRP A CD1 1 
ATOM   2368 C  CD2 . TRP A 1 333 ? 125.337 90.057  122.522 1.00 62.27  ? 414 TRP A CD2 1 
ATOM   2369 N  NE1 . TRP A 1 333 ? 125.759 87.893  122.916 1.00 62.27  ? 414 TRP A NE1 1 
ATOM   2370 C  CE2 . TRP A 1 333 ? 125.641 89.115  123.523 1.00 62.27  ? 414 TRP A CE2 1 
ATOM   2371 C  CE3 . TRP A 1 333 ? 125.164 91.395  122.886 1.00 62.27  ? 414 TRP A CE3 1 
ATOM   2372 C  CZ2 . TRP A 1 333 ? 125.775 89.469  124.863 1.00 62.27  ? 414 TRP A CZ2 1 
ATOM   2373 C  CZ3 . TRP A 1 333 ? 125.299 91.743  124.216 1.00 62.27  ? 414 TRP A CZ3 1 
ATOM   2374 C  CH2 . TRP A 1 333 ? 125.601 90.784  125.188 1.00 62.27  ? 414 TRP A CH2 1 
ATOM   2375 N  N   . ALA A 1 334 ? 126.563 90.976  116.800 1.00 66.49  ? 415 ALA A N   1 
ATOM   2376 C  CA  . ALA A 1 334 ? 126.293 91.059  115.375 1.00 66.49  ? 415 ALA A CA  1 
ATOM   2377 C  C   . ALA A 1 334 ? 126.817 89.818  114.655 1.00 66.49  ? 415 ALA A C   1 
ATOM   2378 O  O   . ALA A 1 334 ? 127.729 89.132  115.120 1.00 66.49  ? 415 ALA A O   1 
ATOM   2379 C  CB  . ALA A 1 334 ? 126.915 92.324  114.784 1.00 66.49  ? 415 ALA A CB  1 
ATOM   2380 N  N   . ASN A 1 335 ? 126.222 89.534  113.501 1.00 69.64  ? 416 ASN A N   1 
ATOM   2381 C  CA  . ASN A 1 335 ? 126.621 88.394  112.676 1.00 69.64  ? 416 ASN A CA  1 
ATOM   2382 C  C   . ASN A 1 335 ? 127.724 88.803  111.700 1.00 69.64  ? 416 ASN A C   1 
ATOM   2383 O  O   . ASN A 1 335 ? 127.616 88.650  110.484 1.00 69.64  ? 416 ASN A O   1 
ATOM   2384 C  CB  . ASN A 1 335 ? 125.411 87.826  111.940 1.00 69.64  ? 416 ASN A CB  1 
ATOM   2385 C  CG  . ASN A 1 335 ? 124.387 87.224  112.880 1.00 69.64  ? 416 ASN A CG  1 
ATOM   2386 O  OD1 . ASN A 1 335 ? 124.735 86.518  113.827 1.00 69.64  ? 416 ASN A OD1 1 
ATOM   2387 N  ND2 . ASN A 1 335 ? 123.113 87.500  112.624 1.00 69.64  ? 416 ASN A ND2 1 
ATOM   2388 N  N   . LYS A 1 336 ? 128.806 89.336  112.263 1.00 65.94  ? 417 LYS A N   1 
ATOM   2389 C  CA  . LYS A 1 336 ? 129.927 89.828  111.479 1.00 65.94  ? 417 LYS A CA  1 
ATOM   2390 C  C   . LYS A 1 336 ? 131.229 89.380  112.124 1.00 65.94  ? 417 LYS A C   1 
ATOM   2391 O  O   . LYS A 1 336 ? 131.252 88.907  113.263 1.00 65.94  ? 417 LYS A O   1 
ATOM   2392 C  CB  . LYS A 1 336 ? 129.903 91.358  111.358 1.00 65.94  ? 417 LYS A CB  1 
ATOM   2393 C  CG  . LYS A 1 336 ? 128.750 91.907  110.534 1.00 65.94  ? 417 LYS A CG  1 
ATOM   2394 C  CD  . LYS A 1 336 ? 128.909 93.400  110.297 1.00 65.94  ? 417 LYS A CD  1 
ATOM   2395 C  CE  . LYS A 1 336 ? 127.748 93.961  109.493 1.00 65.94  ? 417 LYS A CE  1 
ATOM   2396 N  NZ  . LYS A 1 336 ? 127.645 95.440  109.627 1.00 65.94  ? 417 LYS A NZ  1 
ATOM   2397 N  N   . GLU A 1 337 ? 132.318 89.533  111.377 1.00 66.99  ? 418 GLU A N   1 
ATOM   2398 C  CA  . GLU A 1 337 ? 133.655 89.272  111.891 1.00 66.99  ? 418 GLU A CA  1 
ATOM   2399 C  C   . GLU A 1 337 ? 134.233 90.465  112.640 1.00 66.99  ? 418 GLU A C   1 
ATOM   2400 O  O   . GLU A 1 337 ? 135.348 90.373  113.162 1.00 66.99  ? 418 GLU A O   1 
ATOM   2401 C  CB  . GLU A 1 337 ? 134.594 88.874  110.749 1.00 66.99  ? 418 GLU A CB  1 
ATOM   2402 C  CG  . GLU A 1 337 ? 134.272 87.526  110.124 1.00 66.99  ? 418 GLU A CG  1 
ATOM   2403 C  CD  . GLU A 1 337 ? 134.514 87.505  108.627 1.00 66.99  ? 418 GLU A CD  1 
ATOM   2404 O  OE1 . GLU A 1 337 ? 133.991 88.397  107.926 1.00 66.99  ? 418 GLU A OE1 1 
ATOM   2405 O  OE2 . GLU A 1 337 ? 135.226 86.596  108.151 1.00 66.99  ? 418 GLU A OE2 1 
ATOM   2406 N  N   . CYS A 1 338 ? 133.504 91.572  112.701 1.00 67.39  ? 419 CYS A N   1 
ATOM   2407 C  CA  . CYS A 1 338 ? 133.900 92.766  113.433 1.00 67.39  ? 419 CYS A CA  1 
ATOM   2408 C  C   . CYS A 1 338 ? 132.886 93.040  114.541 1.00 67.39  ? 419 CYS A C   1 
ATOM   2409 O  O   . CYS A 1 338 ? 131.989 92.237  114.811 1.00 67.39  ? 419 CYS A O   1 
ATOM   2410 C  CB  . CYS A 1 338 ? 134.016 93.971  112.497 1.00 67.39  ? 419 CYS A CB  1 
ATOM   2411 S  SG  . CYS A 1 338 ? 135.202 93.819  111.153 1.00 67.39  ? 419 CYS A SG  1 
ATOM   2412 N  N   . PHE A 1 339 ? 133.040 94.195  115.184 1.00 60.73  ? 420 PHE A N   1 
ATOM   2413 C  CA  . PHE A 1 339 ? 132.093 94.670  116.180 1.00 60.73  ? 420 PHE A CA  1 
ATOM   2414 C  C   . PHE A 1 339 ? 131.236 95.831  115.700 1.00 60.73  ? 420 PHE A C   1 
ATOM   2415 O  O   . PHE A 1 339 ? 130.128 96.010  116.210 1.00 60.73  ? 420 PHE A O   1 
ATOM   2416 C  CB  . PHE A 1 339 ? 132.832 95.084  117.458 1.00 60.73  ? 420 PHE A CB  1 
ATOM   2417 C  CG  . PHE A 1 339 ? 133.194 93.932  118.351 1.00 60.73  ? 420 PHE A CG  1 
ATOM   2418 C  CD1 . PHE A 1 339 ? 132.532 92.720  118.244 1.00 60.73  ? 420 PHE A CD1 1 
ATOM   2419 C  CD2 . PHE A 1 339 ? 134.194 94.062  119.299 1.00 60.73  ? 420 PHE A CD2 1 
ATOM   2420 C  CE1 . PHE A 1 339 ? 132.861 91.661  119.066 1.00 60.73  ? 420 PHE A CE1 1 
ATOM   2421 C  CE2 . PHE A 1 339 ? 134.528 93.006  120.123 1.00 60.73  ? 420 PHE A CE2 1 
ATOM   2422 C  CZ  . PHE A 1 339 ? 133.860 91.804  120.006 1.00 60.73  ? 420 PHE A CZ  1 
ATOM   2423 N  N   . ASN A 1 340 ? 131.712 96.605  114.718 1.00 58.76  ? 421 ASN A N   1 
ATOM   2424 C  CA  . ASN A 1 340 ? 130.983 97.724  114.127 1.00 58.76  ? 421 ASN A CA  1 
ATOM   2425 C  C   . ASN A 1 340 ? 130.522 98.704  115.200 1.00 58.76  ? 421 ASN A C   1 
ATOM   2426 O  O   . ASN A 1 340 ? 129.338 98.717  115.561 1.00 58.76  ? 421 ASN A O   1 
ATOM   2427 C  CB  . ASN A 1 340 ? 129.789 97.218  113.313 1.00 58.76  ? 421 ASN A CB  1 
ATOM   2428 C  CG  . ASN A 1 340 ? 129.120 98.317  112.505 1.00 58.76  ? 421 ASN A CG  1 
ATOM   2429 O  OD1 . ASN A 1 340 ? 129.521 99.480  112.559 1.00 58.76  ? 421 ASN A OD1 1 
ATOM   2430 N  ND2 . ASN A 1 340 ? 128.093 97.949  111.748 1.00 58.76  ? 421 ASN A ND2 1 
ATOM   2431 N  N   . PRO A 1 341 ? 131.425 99.518  115.745 1.00 55.65  ? 422 PRO A N   1 
ATOM   2432 C  CA  . PRO A 1 341 ? 131.050 100.449 116.817 1.00 55.65  ? 422 PRO A CA  1 
ATOM   2433 C  C   . PRO A 1 341 ? 129.970 101.421 116.367 1.00 55.65  ? 422 PRO A C   1 
ATOM   2434 O  O   . PRO A 1 341 ? 129.735 101.628 115.176 1.00 55.65  ? 422 PRO A O   1 
ATOM   2435 C  CB  . PRO A 1 341 ? 132.358 101.185 117.132 1.00 55.65  ? 422 PRO A CB  1 
ATOM   2436 C  CG  . PRO A 1 341 ? 133.438 100.439 116.411 1.00 55.65  ? 422 PRO A CG  1 
ATOM   2437 C  CD  . PRO A 1 341 ? 132.793 99.753  115.259 1.00 55.65  ? 422 PRO A CD  1 
ATOM   2438 N  N   . CYS A 1 342 ? 129.318 102.046 117.348 1.00 57.38  ? 423 CYS A N   1 
ATOM   2439 C  CA  . CYS A 1 342 ? 128.239 102.982 117.085 1.00 57.38  ? 423 CYS A CA  1 
ATOM   2440 C  C   . CYS A 1 342 ? 128.223 104.013 118.203 1.00 57.38  ? 423 CYS A C   1 
ATOM   2441 O  O   . CYS A 1 342 ? 128.814 103.809 119.267 1.00 57.38  ? 423 CYS A O   1 
ATOM   2442 C  CB  . CYS A 1 342 ? 126.877 102.275 116.988 1.00 57.38  ? 423 CYS A CB  1 
ATOM   2443 S  SG  . CYS A 1 342 ? 126.712 100.957 115.739 1.00 57.38  ? 423 CYS A SG  1 
ATOM   2444 N  N   . PHE A 1 343 ? 127.527 105.121 117.967 1.00 56.57  ? 424 PHE A N   1 
ATOM   2445 C  CA  . PHE A 1 343 ? 127.504 106.191 118.950 1.00 56.57  ? 424 PHE A CA  1 
ATOM   2446 C  C   . PHE A 1 343 ? 126.109 106.788 119.033 1.00 56.57  ? 424 PHE A C   1 
ATOM   2447 O  O   . PHE A 1 343 ? 125.237 106.511 118.207 1.00 56.57  ? 424 PHE A O   1 
ATOM   2448 C  CB  . PHE A 1 343 ? 128.532 107.274 118.617 1.00 56.57  ? 424 PHE A CB  1 
ATOM   2449 C  CG  . PHE A 1 343 ? 128.159 108.124 117.436 1.00 56.57  ? 424 PHE A CG  1 
ATOM   2450 C  CD1 . PHE A 1 343 ? 128.523 107.745 116.155 1.00 56.57  ? 424 PHE A CD1 1 
ATOM   2451 C  CD2 . PHE A 1 343 ? 127.432 109.292 117.601 1.00 56.57  ? 424 PHE A CD2 1 
ATOM   2452 C  CE1 . PHE A 1 343 ? 128.181 108.520 115.063 1.00 56.57  ? 424 PHE A CE1 1 
ATOM   2453 C  CE2 . PHE A 1 343 ? 127.081 110.068 116.512 1.00 56.57  ? 424 PHE A CE2 1 
ATOM   2454 C  CZ  . PHE A 1 343 ? 127.463 109.686 115.245 1.00 56.57  ? 424 PHE A CZ  1 
ATOM   2455 N  N   . TYR A 1 344 ? 125.913 107.620 120.053 1.00 57.59  ? 425 TYR A N   1 
ATOM   2456 C  CA  . TYR A 1 344 ? 124.703 108.409 120.203 1.00 57.59  ? 425 TYR A CA  1 
ATOM   2457 C  C   . TYR A 1 344 ? 125.068 109.797 120.706 1.00 57.59  ? 425 TYR A C   1 
ATOM   2458 O  O   . TYR A 1 344 ? 125.980 109.960 121.522 1.00 57.59  ? 425 TYR A O   1 
ATOM   2459 C  CB  . TYR A 1 344 ? 123.695 107.741 121.158 1.00 57.59  ? 425 TYR A CB  1 
ATOM   2460 C  CG  . TYR A 1 344 ? 124.138 107.652 122.604 1.00 57.59  ? 425 TYR A CG  1 
ATOM   2461 C  CD1 . TYR A 1 344 ? 124.728 106.498 123.100 1.00 57.59  ? 425 TYR A CD1 1 
ATOM   2462 C  CD2 . TYR A 1 344 ? 123.940 108.712 123.481 1.00 57.59  ? 425 TYR A CD2 1 
ATOM   2463 C  CE1 . TYR A 1 344 ? 125.124 106.410 124.420 1.00 57.59  ? 425 TYR A CE1 1 
ATOM   2464 C  CE2 . TYR A 1 344 ? 124.339 108.634 124.799 1.00 57.59  ? 425 TYR A CE2 1 
ATOM   2465 C  CZ  . TYR A 1 344 ? 124.926 107.481 125.264 1.00 57.59  ? 425 TYR A CZ  1 
ATOM   2466 O  OH  . TYR A 1 344 ? 125.322 107.403 126.579 1.00 57.59  ? 425 TYR A OH  1 
ATOM   2467 N  N   . VAL A 1 345 ? 124.350 110.798 120.200 1.00 57.86  ? 426 VAL A N   1 
ATOM   2468 C  CA  . VAL A 1 345 ? 124.517 112.187 120.616 1.00 57.86  ? 426 VAL A CA  1 
ATOM   2469 C  C   . VAL A 1 345 ? 123.148 112.758 120.954 1.00 57.86  ? 426 VAL A C   1 
ATOM   2470 O  O   . VAL A 1 345 ? 122.197 112.608 120.179 1.00 57.86  ? 426 VAL A O   1 
ATOM   2471 C  CB  . VAL A 1 345 ? 125.203 113.047 119.536 1.00 57.86  ? 426 VAL A CB  1 
ATOM   2472 C  CG1 . VAL A 1 345 ? 125.520 114.426 120.083 1.00 57.86  ? 426 VAL A CG1 1 
ATOM   2473 C  CG2 . VAL A 1 345 ? 126.473 112.379 119.046 1.00 57.86  ? 426 VAL A CG2 1 
ATOM   2474 N  N   . GLU A 1 346 ? 123.049 113.415 122.106 1.00 61.43  ? 427 GLU A N   1 
ATOM   2475 C  CA  . GLU A 1 346 ? 121.809 114.041 122.528 1.00 61.43  ? 427 GLU A CA  1 
ATOM   2476 C  C   . GLU A 1 346 ? 121.656 115.414 121.877 1.00 61.43  ? 427 GLU A C   1 
ATOM   2477 O  O   . GLU A 1 346 ? 122.579 115.948 121.256 1.00 61.43  ? 427 GLU A O   1 
ATOM   2478 C  CB  . GLU A 1 346 ? 121.765 114.168 124.049 1.00 61.43  ? 427 GLU A CB  1 
ATOM   2479 C  CG  . GLU A 1 346 ? 121.734 112.841 124.786 1.00 61.43  ? 427 GLU A CG  1 
ATOM   2480 C  CD  . GLU A 1 346 ? 122.108 112.982 126.248 1.00 61.43  ? 427 GLU A CD  1 
ATOM   2481 O  OE1 . GLU A 1 346 ? 122.335 114.126 126.696 1.00 61.43  ? 427 GLU A OE1 1 
ATOM   2482 O  OE2 . GLU A 1 346 ? 122.182 111.951 126.948 1.00 61.43  ? 427 GLU A OE2 1 
ATOM   2483 N  N   . LEU A 1 347 ? 120.467 115.988 122.027 1.00 61.03  ? 428 LEU A N   1 
ATOM   2484 C  CA  . LEU A 1 347 ? 120.185 117.315 121.490 1.00 61.03  ? 428 LEU A CA  1 
ATOM   2485 C  C   . LEU A 1 347 ? 119.559 118.212 122.554 1.00 61.03  ? 428 LEU A C   1 
ATOM   2486 O  O   . LEU A 1 347 ? 119.668 119.437 122.491 1.00 61.03  ? 428 LEU A O   1 
ATOM   2487 C  CB  . LEU A 1 347 ? 119.262 117.219 120.274 1.00 61.03  ? 428 LEU A CB  1 
ATOM   2488 C  CG  . LEU A 1 347 ? 119.801 116.442 119.072 1.00 61.03  ? 428 LEU A CG  1 
ATOM   2489 C  CD1 . LEU A 1 347 ? 118.666 116.018 118.154 1.00 61.03  ? 428 LEU A CD1 1 
ATOM   2490 C  CD2 . LEU A 1 347 ? 120.828 117.267 118.315 1.00 61.03  ? 428 LEU A CD2 1 
ATOM   2491 N  N   . ASN A 1 362 ? 114.022 117.149 124.691 1.00 65.81  ? 443 ASN A N   1 
ATOM   2492 C  CA  . ASN A 1 362 ? 114.953 117.058 123.572 1.00 65.81  ? 443 ASN A CA  1 
ATOM   2493 C  C   . ASN A 1 362 ? 115.053 115.625 123.062 1.00 65.81  ? 443 ASN A C   1 
ATOM   2494 O  O   . ASN A 1 362 ? 114.677 114.682 123.757 1.00 65.81  ? 443 ASN A O   1 
ATOM   2495 C  CB  . ASN A 1 362 ? 116.334 117.572 123.982 1.00 65.81  ? 443 ASN A CB  1 
ATOM   2496 C  CG  . ASN A 1 362 ? 117.020 116.666 124.985 1.00 65.81  ? 443 ASN A CG  1 
ATOM   2497 O  OD1 . ASN A 1 362 ? 117.771 115.765 124.613 1.00 65.81  ? 443 ASN A OD1 1 
ATOM   2498 N  ND2 . ASN A 1 362 ? 116.762 116.900 126.267 1.00 65.81  ? 443 ASN A ND2 1 
ATOM   2499 N  N   . SER A 1 363 ? 115.561 115.469 121.844 1.00 63.69  ? 444 SER A N   1 
ATOM   2500 C  CA  . SER A 1 363 ? 115.710 114.166 121.220 1.00 63.69  ? 444 SER A CA  1 
ATOM   2501 C  C   . SER A 1 363 ? 117.190 113.805 121.108 1.00 63.69  ? 444 SER A C   1 
ATOM   2502 O  O   . SER A 1 363 ? 118.073 114.521 121.586 1.00 63.69  ? 444 SER A O   1 
ATOM   2503 C  CB  . SER A 1 363 ? 115.029 114.147 119.850 1.00 63.69  ? 444 SER A CB  1 
ATOM   2504 O  OG  . SER A 1 363 ? 115.116 112.863 119.257 1.00 63.69  ? 444 SER A OG  1 
ATOM   2505 N  N   . MET A 1 364 ? 117.459 112.674 120.462 1.00 63.50  ? 445 MET A N   1 
ATOM   2506 C  CA  . MET A 1 364 ? 118.819 112.169 120.339 1.00 63.50  ? 445 MET A CA  1 
ATOM   2507 C  C   . MET A 1 364 ? 118.943 111.409 119.029 1.00 63.50  ? 445 MET A C   1 
ATOM   2508 O  O   . MET A 1 364 ? 117.947 110.971 118.448 1.00 63.50  ? 445 MET A O   1 
ATOM   2509 C  CB  . MET A 1 364 ? 119.188 111.268 121.521 1.00 63.50  ? 445 MET A CB  1 
ATOM   2510 C  CG  . MET A 1 364 ? 118.367 109.991 121.589 1.00 63.50  ? 445 MET A CG  1 
ATOM   2511 S  SD  . MET A 1 364 ? 118.824 108.934 122.973 1.00 63.50  ? 445 MET A SD  1 
ATOM   2512 C  CE  . MET A 1 364 ? 120.408 108.323 122.414 1.00 63.50  ? 445 MET A CE  1 
ATOM   2513 N  N   . VAL A 1 365 ? 120.184 111.258 118.571 1.00 61.77  ? 446 VAL A N   1 
ATOM   2514 C  CA  . VAL A 1 365 ? 120.482 110.557 117.329 1.00 61.77  ? 446 VAL A CA  1 
ATOM   2515 C  C   . VAL A 1 365 ? 121.478 109.442 117.613 1.00 61.77  ? 446 VAL A C   1 
ATOM   2516 O  O   . VAL A 1 365 ? 122.499 109.658 118.276 1.00 61.77  ? 446 VAL A O   1 
ATOM   2517 C  CB  . VAL A 1 365 ? 121.022 111.515 116.245 1.00 61.77  ? 446 VAL A CB  1 
ATOM   2518 C  CG1 . VAL A 1 365 ? 119.901 112.394 115.713 1.00 61.77  ? 446 VAL A CG1 1 
ATOM   2519 C  CG2 . VAL A 1 365 ? 122.150 112.372 116.795 1.00 61.77  ? 446 VAL A CG2 1 
ATOM   2520 N  N   . ALA A 1 366 ? 121.176 108.247 117.113 1.00 61.51  ? 447 ALA A N   1 
ATOM   2521 C  CA  . ALA A 1 366 ? 122.060 107.094 117.211 1.00 61.51  ? 447 ALA A CA  1 
ATOM   2522 C  C   . ALA A 1 366 ? 122.571 106.760 115.819 1.00 61.51  ? 447 ALA A C   1 
ATOM   2523 O  O   . ALA A 1 366 ? 121.776 106.502 114.910 1.00 61.51  ? 447 ALA A O   1 
ATOM   2524 C  CB  . ALA A 1 366 ? 121.337 105.890 117.817 1.00 61.51  ? 447 ALA A CB  1 
ATOM   2525 N  N   . LEU A 1 367 ? 123.893 106.759 115.654 1.00 59.04  ? 448 LEU A N   1 
ATOM   2526 C  CA  . LEU A 1 367 ? 124.485 106.688 114.326 1.00 59.04  ? 448 LEU A CA  1 
ATOM   2527 C  C   . LEU A 1 367 ? 125.678 105.744 114.317 1.00 59.04  ? 448 LEU A C   1 
ATOM   2528 O  O   . LEU A 1 367 ? 126.425 105.669 115.299 1.00 59.04  ? 448 LEU A O   1 
ATOM   2529 C  CB  . LEU A 1 367 ? 124.934 108.076 113.856 1.00 59.04  ? 448 LEU A CB  1 
ATOM   2530 C  CG  . LEU A 1 367 ? 123.900 109.200 113.772 1.00 59.04  ? 448 LEU A CG  1 
ATOM   2531 C  CD1 . LEU A 1 367 ? 124.552 110.491 113.298 1.00 59.04  ? 448 LEU A CD1 1 
ATOM   2532 C  CD2 . LEU A 1 367 ? 122.738 108.822 112.885 1.00 59.04  ? 448 LEU A CD2 1 
ATOM   2533 N  N   . CYS A 1 368 ? 125.848 105.033 113.201 1.00 60.22  ? 449 CYS A N   1 
ATOM   2534 C  CA  . CYS A 1 368 ? 127.079 104.321 112.884 1.00 60.22  ? 449 CYS A CA  1 
ATOM   2535 C  C   . CYS A 1 368 ? 126.991 103.770 111.471 1.00 60.22  ? 449 CYS A C   1 
ATOM   2536 O  O   . CYS A 1 368 ? 125.911 103.386 111.015 1.00 60.22  ? 449 CYS A O   1 
ATOM   2537 C  CB  . CYS A 1 368 ? 127.374 103.192 113.869 1.00 60.22  ? 449 CYS A CB  1 
ATOM   2538 S  SG  . CYS A 1 368 ? 126.137 101.904 114.034 1.00 60.22  ? 449 CYS A SG  1 
ATOM   2539 N  N   . GLY A 1 369 ? 128.134 103.727 110.794 1.00 60.69  ? 450 GLY A N   1 
ATOM   2540 C  CA  . GLY A 1 369 ? 128.169 103.331 109.402 1.00 60.69  ? 450 GLY A CA  1 
ATOM   2541 C  C   . GLY A 1 369 ? 129.125 102.199 109.095 1.00 60.69  ? 450 GLY A C   1 
ATOM   2542 O  O   . GLY A 1 369 ? 129.559 101.471 109.993 1.00 60.69  ? 450 GLY A O   1 
ATOM   2543 N  N   . SER A 1 370 ? 129.463 102.053 107.816 1.00 59.78  ? 451 SER A N   1 
ATOM   2544 C  CA  . SER A 1 370 ? 130.272 100.938 107.344 1.00 59.78  ? 451 SER A CA  1 
ATOM   2545 C  C   . SER A 1 370 ? 131.482 101.443 106.571 1.00 59.78  ? 451 SER A C   1 
ATOM   2546 O  O   . SER A 1 370 ? 131.808 102.634 106.624 1.00 59.78  ? 451 SER A O   1 
ATOM   2547 C  CB  . SER A 1 370 ? 129.435 99.999  106.474 1.00 59.78  ? 451 SER A CB  1 
ATOM   2548 O  OG  . SER A 1 370 ? 128.902 100.683 105.354 1.00 59.78  ? 451 SER A OG  1 
ATOM   2549 N  N   . ARG A 1 371 ? 132.158 100.541 105.856 1.00 62.35  ? 452 ARG A N   1 
ATOM   2550 C  CA  . ARG A 1 371 ? 133.354 100.909 105.108 1.00 62.35  ? 452 ARG A CA  1 
ATOM   2551 C  C   . ARG A 1 371 ? 133.061 101.892 103.982 1.00 62.35  ? 452 ARG A C   1 
ATOM   2552 O  O   . ARG A 1 371 ? 134.005 102.441 103.403 1.00 62.35  ? 452 ARG A O   1 
ATOM   2553 C  CB  . ARG A 1 371 ? 134.028 99.659  104.541 1.00 62.35  ? 452 ARG A CB  1 
ATOM   2554 C  CG  . ARG A 1 371 ? 134.356 98.602  105.583 1.00 62.35  ? 452 ARG A CG  1 
ATOM   2555 C  CD  . ARG A 1 371 ? 134.827 97.313  104.932 1.00 62.35  ? 452 ARG A CD  1 
ATOM   2556 N  NE  . ARG A 1 371 ? 135.019 96.245  105.906 1.00 62.35  ? 452 ARG A NE  1 
ATOM   2557 C  CZ  . ARG A 1 371 ? 135.267 94.981  105.593 1.00 62.35  ? 452 ARG A CZ  1 
ATOM   2558 N  NH1 . ARG A 1 371 ? 135.363 94.587  104.333 1.00 62.35  ? 452 ARG A NH1 1 
ATOM   2559 N  NH2 . ARG A 1 371 ? 135.424 94.089  106.567 1.00 62.35  ? 452 ARG A NH2 1 
ATOM   2560 N  N   . GLU A 1 372 ? 131.789 102.107 103.646 1.00 60.46  ? 453 GLU A N   1 
ATOM   2561 C  CA  . GLU A 1 372 ? 131.434 103.107 102.646 1.00 60.46  ? 453 GLU A CA  1 
ATOM   2562 C  C   . GLU A 1 372 ? 132.020 104.459 103.026 1.00 60.46  ? 453 GLU A C   1 
ATOM   2563 O  O   . GLU A 1 372 ? 131.941 104.885 104.181 1.00 60.46  ? 453 GLU A O   1 
ATOM   2564 C  CB  . GLU A 1 372 ? 129.915 103.204 102.507 1.00 60.46  ? 453 GLU A CB  1 
ATOM   2565 C  CG  . GLU A 1 372 ? 129.223 101.863 102.329 1.00 60.46  ? 453 GLU A CG  1 
ATOM   2566 C  CD  . GLU A 1 372 ? 129.800 101.060 101.179 1.00 60.46  ? 453 GLU A CD  1 
ATOM   2567 O  OE1 . GLU A 1 372 ? 129.619 101.472 100.014 1.00 60.46  ? 453 GLU A OE1 1 
ATOM   2568 O  OE2 . GLU A 1 372 ? 130.435 100.016 101.441 1.00 60.46  ? 453 GLU A OE2 1 
ATOM   2569 N  N   . ARG A 1 373 ? 132.615 105.128 102.045 1.00 55.29  ? 454 ARG A N   1 
ATOM   2570 C  CA  . ARG A 1 373 ? 133.464 106.277 102.300 1.00 55.29  ? 454 ARG A CA  1 
ATOM   2571 C  C   . ARG A 1 373 ? 132.670 107.576 102.151 1.00 55.29  ? 454 ARG A C   1 
ATOM   2572 O  O   . ARG A 1 373 ? 131.654 107.642 101.454 1.00 55.29  ? 454 ARG A O   1 
ATOM   2573 C  CB  . ARG A 1 373 ? 134.669 106.223 101.362 1.00 55.29  ? 454 ARG A CB  1 
ATOM   2574 C  CG  . ARG A 1 373 ? 135.713 107.305 101.521 1.00 55.29  ? 454 ARG A CG  1 
ATOM   2575 C  CD  . ARG A 1 373 ? 136.850 107.014 100.560 1.00 55.29  ? 454 ARG A CD  1 
ATOM   2576 N  NE  . ARG A 1 373 ? 137.559 105.807 100.966 1.00 55.29  ? 454 ARG A NE  1 
ATOM   2577 C  CZ  . ARG A 1 373 ? 138.488 105.196 100.244 1.00 55.29  ? 454 ARG A CZ  1 
ATOM   2578 N  NH1 . ARG A 1 373 ? 138.826 105.631 99.042  1.00 55.29  ? 454 ARG A NH1 1 
ATOM   2579 N  NH2 . ARG A 1 373 ? 139.083 104.113 100.735 1.00 55.29  ? 454 ARG A NH2 1 
ATOM   2580 N  N   . LEU A 1 374 ? 133.147 108.617 102.832 1.00 56.52  ? 455 LEU A N   1 
ATOM   2581 C  CA  . LEU A 1 374 ? 132.426 109.880 102.912 1.00 56.52  ? 455 LEU A CA  1 
ATOM   2582 C  C   . LEU A 1 374 ? 132.249 110.512 101.535 1.00 56.52  ? 455 LEU A C   1 
ATOM   2583 O  O   . LEU A 1 374 ? 133.004 110.244 100.596 1.00 56.52  ? 455 LEU A O   1 
ATOM   2584 C  CB  . LEU A 1 374 ? 133.159 110.856 103.832 1.00 56.52  ? 455 LEU A CB  1 
ATOM   2585 C  CG  . LEU A 1 374 ? 132.985 110.660 105.338 1.00 56.52  ? 455 LEU A CG  1 
ATOM   2586 C  CD1 . LEU A 1 374 ? 134.233 111.101 106.084 1.00 56.52  ? 455 LEU A CD1 1 
ATOM   2587 C  CD2 . LEU A 1 374 ? 131.767 111.420 105.831 1.00 56.52  ? 455 LEU A CD2 1 
ATOM   2588 N  N   . GLY A 1 375 ? 131.235 111.361 101.429 1.00 57.18  ? 456 GLY A N   1 
ATOM   2589 C  CA  . GLY A 1 375 ? 130.944 112.041 100.182 1.00 57.18  ? 456 GLY A CA  1 
ATOM   2590 C  C   . GLY A 1 375 ? 129.700 112.886 100.334 1.00 57.18  ? 456 GLY A C   1 
ATOM   2591 O  O   . GLY A 1 375 ? 129.189 113.092 101.440 1.00 57.18  ? 456 GLY A O   1 
ATOM   2592 N  N   . SER A 1 376 ? 129.213 113.378 99.194  1.00 56.61  ? 457 SER A N   1 
ATOM   2593 C  CA  . SER A 1 376 ? 128.000 114.186 99.193  1.00 56.61  ? 457 SER A CA  1 
ATOM   2594 C  C   . SER A 1 376 ? 126.764 113.374 99.559  1.00 56.61  ? 457 SER A C   1 
ATOM   2595 O  O   . SER A 1 376 ? 125.704 113.956 99.811  1.00 56.61  ? 457 SER A O   1 
ATOM   2596 C  CB  . SER A 1 376 ? 127.810 114.841 97.824  1.00 56.61  ? 457 SER A CB  1 
ATOM   2597 O  OG  . SER A 1 376 ? 127.722 113.866 96.800  1.00 56.61  ? 457 SER A OG  1 
ATOM   2598 N  N   . TRP A 1 377 ? 126.878 112.047 99.594  1.00 57.42  ? 458 TRP A N   1 
ATOM   2599 C  CA  . TRP A 1 377 ? 125.757 111.167 99.895  1.00 57.42  ? 458 TRP A CA  1 
ATOM   2600 C  C   . TRP A 1 377 ? 125.623 110.853 101.379 1.00 57.42  ? 458 TRP A C   1 
ATOM   2601 O  O   . TRP A 1 377 ? 124.684 110.146 101.761 1.00 57.42  ? 458 TRP A O   1 
ATOM   2602 C  CB  . TRP A 1 377 ? 125.907 109.860 99.115  1.00 57.42  ? 458 TRP A CB  1 
ATOM   2603 C  CG  . TRP A 1 377 ? 127.292 109.294 99.193  1.00 57.42  ? 458 TRP A CG  1 
ATOM   2604 C  CD1 . TRP A 1 377 ? 127.751 108.377 100.091 1.00 57.42  ? 458 TRP A CD1 1 
ATOM   2605 C  CD2 . TRP A 1 377 ? 128.403 109.622 98.350  1.00 57.42  ? 458 TRP A CD2 1 
ATOM   2606 N  NE1 . TRP A 1 377 ? 129.077 108.107 99.856  1.00 57.42  ? 458 TRP A NE1 1 
ATOM   2607 C  CE2 . TRP A 1 377 ? 129.502 108.859 98.793  1.00 57.42  ? 458 TRP A CE2 1 
ATOM   2608 C  CE3 . TRP A 1 377 ? 128.576 110.484 97.263  1.00 57.42  ? 458 TRP A CE3 1 
ATOM   2609 C  CZ2 . TRP A 1 377 ? 130.753 108.932 98.187  1.00 57.42  ? 458 TRP A CZ2 1 
ATOM   2610 C  CZ3 . TRP A 1 377 ? 129.820 110.554 96.662  1.00 57.42  ? 458 TRP A CZ3 1 
ATOM   2611 C  CH2 . TRP A 1 377 ? 130.892 109.782 97.126  1.00 57.42  ? 458 TRP A CH2 1 
ATOM   2612 N  N   . SER A 1 378 ? 126.525 111.353 102.217 1.00 58.39  ? 459 SER A N   1 
ATOM   2613 C  CA  . SER A 1 378 ? 126.550 111.016 103.632 1.00 58.39  ? 459 SER A CA  1 
ATOM   2614 C  C   . SER A 1 378 ? 125.970 112.147 104.472 1.00 58.39  ? 459 SER A C   1 
ATOM   2615 O  O   . SER A 1 378 ? 126.114 113.328 104.147 1.00 58.39  ? 459 SER A O   1 
ATOM   2616 C  CB  . SER A 1 378 ? 127.977 110.712 104.091 1.00 58.39  ? 459 SER A CB  1 
ATOM   2617 O  OG  . SER A 1 378 ? 128.816 111.841 103.926 1.00 58.39  ? 459 SER A OG  1 
ATOM   2618 N  N   . TRP A 1 379 ? 125.312 111.767 105.563 1.00 61.15  ? 460 TRP A N   1 
ATOM   2619 C  CA  . TRP A 1 379 ? 124.732 112.727 106.496 1.00 61.15  ? 460 TRP A CA  1 
ATOM   2620 C  C   . TRP A 1 379 ? 124.699 112.162 107.913 1.00 61.15  ? 460 TRP A C   1 
ATOM   2621 O  O   . TRP A 1 379 ? 123.722 112.340 108.640 1.00 61.15  ? 460 TRP A O   1 
ATOM   2622 C  CB  . TRP A 1 379 ? 123.322 113.125 106.056 1.00 61.15  ? 460 TRP A CB  1 
ATOM   2623 C  CG  . TRP A 1 379 ? 123.291 114.316 105.150 1.00 61.15  ? 460 TRP A CG  1 
ATOM   2624 C  CD1 . TRP A 1 379 ? 123.118 114.315 103.797 1.00 61.15  ? 460 TRP A CD1 1 
ATOM   2625 C  CD2 . TRP A 1 379 ? 123.432 115.689 105.536 1.00 61.15  ? 460 TRP A CD2 1 
ATOM   2626 N  NE1 . TRP A 1 379 ? 123.146 115.602 103.315 1.00 61.15  ? 460 TRP A NE1 1 
ATOM   2627 C  CE2 . TRP A 1 379 ? 123.337 116.464 104.363 1.00 61.15  ? 460 TRP A CE2 1 
ATOM   2628 C  CE3 . TRP A 1 379 ? 123.631 116.337 106.759 1.00 61.15  ? 460 TRP A CE3 1 
ATOM   2629 C  CZ2 . TRP A 1 379 ? 123.434 117.854 104.378 1.00 61.15  ? 460 TRP A CZ2 1 
ATOM   2630 C  CZ3 . TRP A 1 379 ? 123.727 117.716 106.771 1.00 61.15  ? 460 TRP A CZ3 1 
ATOM   2631 C  CH2 . TRP A 1 379 ? 123.628 118.459 105.589 1.00 61.15  ? 460 TRP A CH2 1 
ATOM   2632 N  N   . SER B 2 2   ? 136.217 127.345 83.093  1.00 72.46  ? 2   SER B N   1 
ATOM   2633 C  CA  . SER B 2 2   ? 134.794 127.364 82.774  1.00 72.46  ? 2   SER B CA  1 
ATOM   2634 C  C   . SER B 2 2   ? 134.037 128.296 83.714  1.00 72.46  ? 2   SER B C   1 
ATOM   2635 O  O   . SER B 2 2   ? 134.175 128.209 84.934  1.00 72.46  ? 2   SER B O   1 
ATOM   2636 C  CB  . SER B 2 2   ? 134.209 125.952 82.847  1.00 72.46  ? 2   SER B CB  1 
ATOM   2637 O  OG  . SER B 2 2   ? 134.640 125.164 81.751  1.00 72.46  ? 2   SER B OG  1 
ATOM   2638 N  N   . VAL B 2 3   ? 133.238 129.190 83.137  1.00 70.17  ? 3   VAL B N   1 
ATOM   2639 C  CA  . VAL B 2 3   ? 132.456 130.165 83.889  1.00 70.17  ? 3   VAL B CA  1 
ATOM   2640 C  C   . VAL B 2 3   ? 130.990 129.986 83.525  1.00 70.17  ? 3   VAL B C   1 
ATOM   2641 O  O   . VAL B 2 3   ? 130.643 129.902 82.341  1.00 70.17  ? 3   VAL B O   1 
ATOM   2642 C  CB  . VAL B 2 3   ? 132.921 131.604 83.605  1.00 70.17  ? 3   VAL B CB  1 
ATOM   2643 C  CG1 . VAL B 2 3   ? 132.096 132.596 84.411  1.00 70.17  ? 3   VAL B CG1 1 
ATOM   2644 C  CG2 . VAL B 2 3   ? 134.402 131.756 83.917  1.00 70.17  ? 3   VAL B CG2 1 
ATOM   2645 N  N   . LEU B 2 4   ? 130.133 129.927 84.541  1.00 68.30  ? 4   LEU B N   1 
ATOM   2646 C  CA  . LEU B 2 4   ? 128.705 129.788 84.302  1.00 68.30  ? 4   LEU B CA  1 
ATOM   2647 C  C   . LEU B 2 4   ? 128.157 131.044 83.637  1.00 68.30  ? 4   LEU B C   1 
ATOM   2648 O  O   . LEU B 2 4   ? 128.750 132.124 83.710  1.00 68.30  ? 4   LEU B O   1 
ATOM   2649 C  CB  . LEU B 2 4   ? 127.968 129.520 85.614  1.00 68.30  ? 4   LEU B CB  1 
ATOM   2650 C  CG  . LEU B 2 4   ? 128.677 128.577 86.586  1.00 68.30  ? 4   LEU B CG  1 
ATOM   2651 C  CD1 . LEU B 2 4   ? 127.985 128.580 87.940  1.00 68.30  ? 4   LEU B CD1 1 
ATOM   2652 C  CD2 . LEU B 2 4   ? 128.749 127.173 86.014  1.00 68.30  ? 4   LEU B CD2 1 
ATOM   2653 N  N   . THR B 2 5   ? 127.010 130.897 82.979  1.00 72.29  ? 5   THR B N   1 
ATOM   2654 C  CA  . THR B 2 5   ? 126.405 131.974 82.209  1.00 72.29  ? 5   THR B CA  1 
ATOM   2655 C  C   . THR B 2 5   ? 125.020 132.287 82.752  1.00 72.29  ? 5   THR B C   1 
ATOM   2656 O  O   . THR B 2 5   ? 124.255 131.376 83.085  1.00 72.29  ? 5   THR B O   1 
ATOM   2657 C  CB  . THR B 2 5   ? 126.311 131.611 80.724  1.00 72.29  ? 5   THR B CB  1 
ATOM   2658 O  OG1 . THR B 2 5   ? 125.339 130.574 80.543  1.00 72.29  ? 5   THR B OG1 1 
ATOM   2659 C  CG2 . THR B 2 5   ? 127.659 131.135 80.203  1.00 72.29  ? 5   THR B CG2 1 
ATOM   2660 N  N   . GLN B 2 6   ? 124.709 133.573 82.838  1.00 77.43  ? 6   GLN B N   1 
ATOM   2661 C  CA  . GLN B 2 6   ? 123.400 134.096 83.185  1.00 77.43  ? 6   GLN B CA  1 
ATOM   2662 C  C   . GLN B 2 6   ? 122.864 134.879 81.993  1.00 77.43  ? 6   GLN B C   1 
ATOM   2663 O  O   . GLN B 2 6   ? 123.642 135.323 81.140  1.00 77.43  ? 6   GLN B O   1 
ATOM   2664 C  CB  . GLN B 2 6   ? 123.487 134.994 84.428  1.00 77.43  ? 6   GLN B CB  1 
ATOM   2665 C  CG  . GLN B 2 6   ? 123.654 134.219 85.726  1.00 77.43  ? 6   GLN B CG  1 
ATOM   2666 C  CD  . GLN B 2 6   ? 123.894 135.119 86.921  1.00 77.43  ? 6   GLN B CD  1 
ATOM   2667 O  OE1 . GLN B 2 6   ? 124.981 135.123 87.500  1.00 77.43  ? 6   GLN B OE1 1 
ATOM   2668 N  NE2 . GLN B 2 6   ? 122.879 135.886 87.300  1.00 77.43  ? 6   GLN B NE2 1 
ATOM   2669 N  N   . PRO B 2 7   ? 121.532 135.052 81.883  1.00 78.85  ? 7   PRO B N   1 
ATOM   2670 C  CA  . PRO B 2 7   ? 120.969 135.638 80.656  1.00 78.85  ? 7   PRO B CA  1 
ATOM   2671 C  C   . PRO B 2 7   ? 121.552 136.999 80.304  1.00 78.85  ? 7   PRO B C   1 
ATOM   2672 O  O   . PRO B 2 7   ? 122.190 137.141 79.255  1.00 78.85  ? 7   PRO B O   1 
ATOM   2673 C  CB  . PRO B 2 7   ? 119.469 135.739 80.969  1.00 78.85  ? 7   PRO B CB  1 
ATOM   2674 C  CG  . PRO B 2 7   ? 119.361 135.607 82.454  1.00 78.85  ? 7   PRO B CG  1 
ATOM   2675 C  CD  . PRO B 2 7   ? 120.481 134.712 82.856  1.00 78.85  ? 7   PRO B CD  1 
ATOM   2676 N  N   . ALA B 2 8   ? 121.383 137.976 81.201  1.00 80.26  ? 8   ALA B N   1 
ATOM   2677 C  CA  . ALA B 2 8   ? 121.857 139.349 81.038  1.00 80.26  ? 8   ALA B CA  1 
ATOM   2678 C  C   . ALA B 2 8   ? 121.260 140.229 82.125  1.00 80.26  ? 8   ALA B C   1 
ATOM   2679 O  O   . ALA B 2 8   ? 121.956 140.644 83.058  1.00 80.26  ? 8   ALA B O   1 
ATOM   2680 C  CB  . ALA B 2 8   ? 121.487 139.926 79.667  1.00 80.26  ? 8   ALA B CB  1 
ATOM   2681 N  N   . SER B 2 9   ? 119.966 140.512 82.002  1.00 82.76  ? 9   SER B N   1 
ATOM   2682 C  CA  . SER B 2 9   ? 119.228 141.306 82.972  1.00 82.76  ? 9   SER B CA  1 
ATOM   2683 C  C   . SER B 2 9   ? 117.744 141.118 82.701  1.00 82.76  ? 9   SER B C   1 
ATOM   2684 O  O   . SER B 2 9   ? 117.298 141.188 81.553  1.00 82.76  ? 9   SER B O   1 
ATOM   2685 C  CB  . SER B 2 9   ? 119.604 142.790 82.900  1.00 82.76  ? 9   SER B CB  1 
ATOM   2686 O  OG  . SER B 2 9   ? 119.421 143.300 81.590  1.00 82.76  ? 9   SER B OG  1 
ATOM   2687 N  N   . VAL B 2 10  ? 116.984 140.878 83.770  1.00 86.08  ? 10  VAL B N   1 
ATOM   2688 C  CA  . VAL B 2 10  ? 115.553 140.628 83.666  1.00 86.08  ? 10  VAL B CA  1 
ATOM   2689 C  C   . VAL B 2 10  ? 114.816 141.569 84.606  1.00 86.08  ? 10  VAL B C   1 
ATOM   2690 O  O   . VAL B 2 10  ? 115.358 142.036 85.611  1.00 86.08  ? 10  VAL B O   1 
ATOM   2691 C  CB  . VAL B 2 10  ? 115.190 139.160 83.983  1.00 86.08  ? 10  VAL B CB  1 
ATOM   2692 C  CG1 . VAL B 2 10  ? 115.756 138.232 82.919  1.00 86.08  ? 10  VAL B CG1 1 
ATOM   2693 C  CG2 . VAL B 2 10  ? 115.700 138.773 85.362  1.00 86.08  ? 10  VAL B CG2 1 
ATOM   2694 N  N   . SER B 2 11  ? 113.562 141.848 84.261  1.00 89.85  ? 11  SER B N   1 
ATOM   2695 C  CA  . SER B 2 11  ? 112.736 142.757 85.042  1.00 89.85  ? 11  SER B CA  1 
ATOM   2696 C  C   . SER B 2 11  ? 111.275 142.494 84.714  1.00 89.85  ? 11  SER B C   1 
ATOM   2697 O  O   . SER B 2 11  ? 110.950 141.856 83.709  1.00 89.85  ? 11  SER B O   1 
ATOM   2698 C  CB  . SER B 2 11  ? 113.097 144.221 84.770  1.00 89.85  ? 11  SER B CB  1 
ATOM   2699 O  OG  . SER B 2 11  ? 112.622 145.063 85.805  1.00 89.85  ? 11  SER B OG  1 
ATOM   2700 N  N   . GLY B 2 12  ? 110.400 142.995 85.577  1.00 92.86  ? 12  GLY B N   1 
ATOM   2701 C  CA  . GLY B 2 12  ? 108.974 142.835 85.373  1.00 92.86  ? 12  GLY B CA  1 
ATOM   2702 C  C   . GLY B 2 12  ? 108.190 143.714 86.318  1.00 92.86  ? 12  GLY B C   1 
ATOM   2703 O  O   . GLY B 2 12  ? 108.753 144.376 87.196  1.00 92.86  ? 12  GLY B O   1 
ATOM   2704 N  N   . SER B 2 13  ? 106.877 143.709 86.122  1.00 96.60  ? 13  SER B N   1 
ATOM   2705 C  CA  . SER B 2 13  ? 105.976 144.495 86.946  1.00 96.60  ? 13  SER B CA  1 
ATOM   2706 C  C   . SER B 2 13  ? 105.716 143.797 88.277  1.00 96.60  ? 13  SER B C   1 
ATOM   2707 O  O   . SER B 2 13  ? 105.858 142.576 88.388  1.00 96.60  ? 13  SER B O   1 
ATOM   2708 C  CB  . SER B 2 13  ? 104.660 144.726 86.208  1.00 96.60  ? 13  SER B CB  1 
ATOM   2709 O  OG  . SER B 2 13  ? 104.862 145.496 85.036  1.00 96.60  ? 13  SER B OG  1 
ATOM   2710 N  N   . PRO B 2 14  ? 105.351 144.554 89.313  1.00 96.67  ? 14  PRO B N   1 
ATOM   2711 C  CA  . PRO B 2 14  ? 104.988 143.925 90.587  1.00 96.67  ? 14  PRO B CA  1 
ATOM   2712 C  C   . PRO B 2 14  ? 103.771 143.025 90.432  1.00 96.67  ? 14  PRO B C   1 
ATOM   2713 O  O   . PRO B 2 14  ? 102.880 143.279 89.619  1.00 96.67  ? 14  PRO B O   1 
ATOM   2714 C  CB  . PRO B 2 14  ? 104.691 145.118 91.502  1.00 96.67  ? 14  PRO B CB  1 
ATOM   2715 C  CG  . PRO B 2 14  ? 105.446 146.253 90.897  1.00 96.67  ? 14  PRO B CG  1 
ATOM   2716 C  CD  . PRO B 2 14  ? 105.395 146.022 89.416  1.00 96.67  ? 14  PRO B CD  1 
ATOM   2717 N  N   . GLY B 2 15  ? 103.744 141.959 91.230  1.00 97.86  ? 15  GLY B N   1 
ATOM   2718 C  CA  . GLY B 2 15  ? 102.704 140.960 91.167  1.00 97.86  ? 15  GLY B CA  1 
ATOM   2719 C  C   . GLY B 2 15  ? 102.994 139.812 90.220  1.00 97.86  ? 15  GLY B C   1 
ATOM   2720 O  O   . GLY B 2 15  ? 102.195 138.874 90.134  1.00 97.86  ? 15  GLY B O   1 
ATOM   2721 N  N   . GLN B 2 16  ? 104.117 139.864 89.510  1.00 97.21  ? 16  GLN B N   1 
ATOM   2722 C  CA  . GLN B 2 16  ? 104.488 138.801 88.590  1.00 97.21  ? 16  GLN B CA  1 
ATOM   2723 C  C   . GLN B 2 16  ? 105.638 137.976 89.156  1.00 97.21  ? 16  GLN B C   1 
ATOM   2724 O  O   . GLN B 2 16  ? 106.327 138.387 90.094  1.00 97.21  ? 16  GLN B O   1 
ATOM   2725 C  CB  . GLN B 2 16  ? 104.884 139.380 87.231  1.00 97.21  ? 16  GLN B CB  1 
ATOM   2726 C  CG  . GLN B 2 16  ? 104.003 140.525 86.762  1.00 97.21  ? 16  GLN B CG  1 
ATOM   2727 C  CD  . GLN B 2 16  ? 104.213 140.856 85.298  1.00 97.21  ? 16  GLN B CD  1 
ATOM   2728 O  OE1 . GLN B 2 16  ? 105.319 141.194 84.878  1.00 97.21  ? 16  GLN B OE1 1 
ATOM   2729 N  NE2 . GLN B 2 16  ? 103.147 140.760 84.511  1.00 97.21  ? 16  GLN B NE2 1 
ATOM   2730 N  N   . SER B 2 17  ? 105.840 136.799 88.572  1.00 93.42  ? 17  SER B N   1 
ATOM   2731 C  CA  . SER B 2 17  ? 106.903 135.887 88.970  1.00 93.42  ? 17  SER B CA  1 
ATOM   2732 C  C   . SER B 2 17  ? 108.020 135.943 87.938  1.00 93.42  ? 17  SER B C   1 
ATOM   2733 O  O   . SER B 2 17  ? 107.767 135.815 86.736  1.00 93.42  ? 17  SER B O   1 
ATOM   2734 C  CB  . SER B 2 17  ? 106.376 134.457 89.106  1.00 93.42  ? 17  SER B CB  1 
ATOM   2735 O  OG  . SER B 2 17  ? 105.295 134.396 90.020  1.00 93.42  ? 17  SER B OG  1 
ATOM   2736 N  N   . ILE B 2 18  ? 109.250 136.132 88.409  1.00 87.13  ? 18  ILE B N   1 
ATOM   2737 C  CA  . ILE B 2 18  ? 110.418 136.251 87.544  1.00 87.13  ? 18  ILE B CA  1 
ATOM   2738 C  C   . ILE B 2 18  ? 111.344 135.071 87.803  1.00 87.13  ? 18  ILE B C   1 
ATOM   2739 O  O   . ILE B 2 18  ? 111.595 134.702 88.957  1.00 87.13  ? 18  ILE B O   1 
ATOM   2740 C  CB  . ILE B 2 18  ? 111.147 137.594 87.755  1.00 87.13  ? 18  ILE B CB  1 
ATOM   2741 C  CG1 . ILE B 2 18  ? 112.397 137.676 86.875  1.00 87.13  ? 18  ILE B CG1 1 
ATOM   2742 C  CG2 . ILE B 2 18  ? 111.489 137.809 89.224  1.00 87.13  ? 18  ILE B CG2 1 
ATOM   2743 C  CD1 . ILE B 2 18  ? 112.107 137.568 85.393  1.00 87.13  ? 18  ILE B CD1 1 
ATOM   2744 N  N   . THR B 2 19  ? 111.833 134.465 86.724  1.00 80.95  ? 19  THR B N   1 
ATOM   2745 C  CA  . THR B 2 19  ? 112.710 133.305 86.796  1.00 80.95  ? 19  THR B CA  1 
ATOM   2746 C  C   . THR B 2 19  ? 114.072 133.658 86.218  1.00 80.95  ? 19  THR B C   1 
ATOM   2747 O  O   . THR B 2 19  ? 114.164 134.150 85.089  1.00 80.95  ? 19  THR B O   1 
ATOM   2748 C  CB  . THR B 2 19  ? 112.115 132.111 86.044  1.00 80.95  ? 19  THR B CB  1 
ATOM   2749 O  OG1 . THR B 2 19  ? 111.959 132.445 84.659  1.00 80.95  ? 19  THR B OG1 1 
ATOM   2750 C  CG2 . THR B 2 19  ? 110.760 131.736 86.626  1.00 80.95  ? 19  THR B CG2 1 
ATOM   2751 N  N   . ILE B 2 20  ? 115.120 133.404 86.995  1.00 74.50  ? 20  ILE B N   1 
ATOM   2752 C  CA  . ILE B 2 20  ? 116.501 133.617 86.578  1.00 74.50  ? 20  ILE B CA  1 
ATOM   2753 C  C   . ILE B 2 20  ? 117.157 132.255 86.409  1.00 74.50  ? 20  ILE B C   1 
ATOM   2754 O  O   . ILE B 2 20  ? 117.100 131.415 87.315  1.00 74.50  ? 20  ILE B O   1 
ATOM   2755 C  CB  . ILE B 2 20  ? 117.272 134.479 87.591  1.00 74.50  ? 20  ILE B CB  1 
ATOM   2756 C  CG1 . ILE B 2 20  ? 116.471 135.733 87.943  1.00 74.50  ? 20  ILE B CG1 1 
ATOM   2757 C  CG2 . ILE B 2 20  ? 118.637 134.855 87.039  1.00 74.50  ? 20  ILE B CG2 1 
ATOM   2758 C  CD1 . ILE B 2 20  ? 117.137 136.614 88.979  1.00 74.50  ? 20  ILE B CD1 1 
ATOM   2759 N  N   . SER B 2 21  ? 117.777 132.038 85.254  1.00 70.48  ? 21  SER B N   1 
ATOM   2760 C  CA  . SER B 2 21  ? 118.377 130.760 84.909  1.00 70.48  ? 21  SER B CA  1 
ATOM   2761 C  C   . SER B 2 21  ? 119.895 130.876 84.882  1.00 70.48  ? 21  SER B C   1 
ATOM   2762 O  O   . SER B 2 21  ? 120.449 131.914 84.510  1.00 70.48  ? 21  SER B O   1 
ATOM   2763 C  CB  . SER B 2 21  ? 117.871 130.266 83.551  1.00 70.48  ? 21  SER B CB  1 
ATOM   2764 O  OG  . SER B 2 21  ? 116.459 130.345 83.475  1.00 70.48  ? 21  SER B OG  1 
ATOM   2765 N  N   . CYS B 2 22  ? 120.563 129.796 85.281  1.00 70.92  ? 22  CYS B N   1 
ATOM   2766 C  CA  . CYS B 2 22  ? 122.021 129.755 85.298  1.00 70.92  ? 22  CYS B CA  1 
ATOM   2767 C  C   . CYS B 2 22  ? 122.464 128.384 84.814  1.00 70.92  ? 22  CYS B C   1 
ATOM   2768 O  O   . CYS B 2 22  ? 122.151 127.374 85.450  1.00 70.92  ? 22  CYS B O   1 
ATOM   2769 C  CB  . CYS B 2 22  ? 122.558 130.036 86.704  1.00 70.92  ? 22  CYS B CB  1 
ATOM   2770 S  SG  . CYS B 2 22  ? 124.356 130.001 86.863  1.00 70.92  ? 22  CYS B SG  1 
ATOM   2771 N  N   . THR B 2 23  ? 123.183 128.346 83.695  1.00 69.16  ? 23  THR B N   1 
ATOM   2772 C  CA  . THR B 2 23  ? 123.632 127.098 83.099  1.00 69.16  ? 23  THR B CA  1 
ATOM   2773 C  C   . THR B 2 23  ? 125.150 127.090 82.977  1.00 69.16  ? 23  THR B C   1 
ATOM   2774 O  O   . THR B 2 23  ? 125.785 128.138 82.822  1.00 69.16  ? 23  THR B O   1 
ATOM   2775 C  CB  . THR B 2 23  ? 122.991 126.869 81.721  1.00 69.16  ? 23  THR B CB  1 
ATOM   2776 O  OG1 . THR B 2 23  ? 123.342 125.567 81.237  1.00 69.16  ? 23  THR B OG1 1 
ATOM   2777 C  CG2 . THR B 2 23  ? 123.451 127.921 80.724  1.00 69.16  ? 23  THR B CG2 1 
ATOM   2778 N  N   . GLY B 2 24  ? 125.727 125.895 83.069  1.00 70.45  ? 24  GLY B N   1 
ATOM   2779 C  CA  . GLY B 2 24  ? 127.164 125.735 82.972  1.00 70.45  ? 24  GLY B CA  1 
ATOM   2780 C  C   . GLY B 2 24  ? 127.576 124.431 82.321  1.00 70.45  ? 24  GLY B C   1 
ATOM   2781 O  O   . GLY B 2 24  ? 127.032 124.050 81.280  1.00 70.45  ? 24  GLY B O   1 
ATOM   2782 N  N   . THR B 2 25  ? 128.535 123.740 82.925  1.00 69.05  ? 25  THR B N   1 
ATOM   2783 C  CA  . THR B 2 25  ? 129.018 122.456 82.437  1.00 69.05  ? 25  THR B CA  1 
ATOM   2784 C  C   . THR B 2 25  ? 128.454 121.337 83.312  1.00 69.05  ? 25  THR B C   1 
ATOM   2785 O  O   . THR B 2 25  ? 127.651 121.573 84.220  1.00 69.05  ? 25  THR B O   1 
ATOM   2786 C  CB  . THR B 2 25  ? 130.548 122.431 82.407  1.00 69.05  ? 25  THR B CB  1 
ATOM   2787 O  OG1 . THR B 2 25  ? 131.051 122.235 83.734  1.00 69.05  ? 25  THR B OG1 1 
ATOM   2788 C  CG2 . THR B 2 25  ? 131.092 123.739 81.854  1.00 69.05  ? 25  THR B CG2 1 
ATOM   2789 N  N   . SER B 2 26  ? 128.877 120.107 83.027  1.00 66.61  ? 26  SER B N   1 
ATOM   2790 C  CA  . SER B 2 26  ? 128.413 118.947 83.776  1.00 66.61  ? 26  SER B CA  1 
ATOM   2791 C  C   . SER B 2 26  ? 129.273 118.636 84.993  1.00 66.61  ? 26  SER B C   1 
ATOM   2792 O  O   . SER B 2 26  ? 128.770 118.039 85.951  1.00 66.61  ? 26  SER B O   1 
ATOM   2793 C  CB  . SER B 2 26  ? 128.364 117.716 82.867  1.00 66.61  ? 26  SER B CB  1 
ATOM   2794 O  OG  . SER B 2 26  ? 129.666 117.325 82.467  1.00 66.61  ? 26  SER B OG  1 
ATOM   2795 N  N   . SER B 2 27  ? 130.545 119.024 84.980  1.00 65.77  ? 27  SER B N   1 
ATOM   2796 C  CA  . SER B 2 27  ? 131.467 118.712 86.063  1.00 65.77  ? 27  SER B CA  1 
ATOM   2797 C  C   . SER B 2 27  ? 131.335 119.650 87.255  1.00 65.77  ? 27  SER B C   1 
ATOM   2798 O  O   . SER B 2 27  ? 131.932 119.381 88.302  1.00 65.77  ? 27  SER B O   1 
ATOM   2799 C  CB  . SER B 2 27  ? 132.910 118.741 85.549  1.00 65.77  ? 27  SER B CB  1 
ATOM   2800 O  OG  . SER B 2 27  ? 133.288 120.052 85.169  1.00 65.77  ? 27  SER B OG  1 
ATOM   2801 N  N   . ASP B 2 28  ? 130.577 120.737 87.129  1.00 67.62  ? 28  ASP B N   1 
ATOM   2802 C  CA  . ASP B 2 28  ? 130.430 121.701 88.212  1.00 67.62  ? 28  ASP B CA  1 
ATOM   2803 C  C   . ASP B 2 28  ? 128.994 121.845 88.688  1.00 67.62  ? 28  ASP B C   1 
ATOM   2804 O  O   . ASP B 2 28  ? 128.748 121.872 89.900  1.00 67.62  ? 28  ASP B O   1 
ATOM   2805 C  CB  . ASP B 2 28  ? 130.983 123.071 87.779  1.00 67.62  ? 28  ASP B CB  1 
ATOM   2806 C  CG  . ASP B 2 28  ? 130.418 123.538 86.451  1.00 67.62  ? 28  ASP B CG  1 
ATOM   2807 O  OD1 . ASP B 2 28  ? 129.525 122.858 85.905  1.00 67.62  ? 28  ASP B OD1 1 
ATOM   2808 O  OD2 . ASP B 2 28  ? 130.871 124.590 85.952  1.00 67.62  ? 28  ASP B OD2 1 
ATOM   2809 N  N   . VAL B 2 29  ? 128.034 121.938 87.773  1.00 65.58  ? 29  VAL B N   1 
ATOM   2810 C  CA  . VAL B 2 29  ? 126.636 122.167 88.114  1.00 65.58  ? 29  VAL B CA  1 
ATOM   2811 C  C   . VAL B 2 29  ? 125.831 120.874 88.067  1.00 65.58  ? 29  VAL B C   1 
ATOM   2812 O  O   . VAL B 2 29  ? 125.166 120.512 89.038  1.00 65.58  ? 29  VAL B O   1 
ATOM   2813 C  CB  . VAL B 2 29  ? 126.012 123.239 87.193  1.00 65.58  ? 29  VAL B CB  1 
ATOM   2814 C  CG1 . VAL B 2 29  ? 124.504 123.281 87.376  1.00 65.58  ? 29  VAL B CG1 1 
ATOM   2815 C  CG2 . VAL B 2 29  ? 126.622 124.597 87.475  1.00 65.58  ? 29  VAL B CG2 1 
ATOM   2816 N  N   . GLY B 2 30  ? 125.880 120.163 86.939  1.00 65.13  ? 30  GLY B N   1 
ATOM   2817 C  CA  . GLY B 2 30  ? 125.043 118.984 86.781  1.00 65.13  ? 30  GLY B CA  1 
ATOM   2818 C  C   . GLY B 2 30  ? 125.376 117.875 87.760  1.00 65.13  ? 30  GLY B C   1 
ATOM   2819 O  O   . GLY B 2 30  ? 124.479 117.213 88.290  1.00 65.13  ? 30  GLY B O   1 
ATOM   2820 N  N   . GLY B 2 31  ? 126.667 117.652 88.012  1.00 63.81  ? 31  GLY B N   1 
ATOM   2821 C  CA  . GLY B 2 31  ? 127.064 116.533 88.852  1.00 63.81  ? 31  GLY B CA  1 
ATOM   2822 C  C   . GLY B 2 31  ? 126.625 116.674 90.297  1.00 63.81  ? 31  GLY B C   1 
ATOM   2823 O  O   . GLY B 2 31  ? 126.130 115.716 90.899  1.00 63.81  ? 31  GLY B O   1 
ATOM   2824 N  N   . TYR B 2 32  ? 126.794 117.860 90.875  1.00 58.94  ? 32  TYR B N   1 
ATOM   2825 C  CA  . TYR B 2 32  ? 126.581 118.074 92.298  1.00 58.94  ? 32  TYR B CA  1 
ATOM   2826 C  C   . TYR B 2 32  ? 125.399 119.003 92.534  1.00 58.94  ? 32  TYR B C   1 
ATOM   2827 O  O   . TYR B 2 32  ? 125.167 119.941 91.764  1.00 58.94  ? 32  TYR B O   1 
ATOM   2828 C  CB  . TYR B 2 32  ? 127.834 118.657 92.956  1.00 58.94  ? 32  TYR B CB  1 
ATOM   2829 C  CG  . TYR B 2 32  ? 129.115 117.985 92.526  1.00 58.94  ? 32  TYR B CG  1 
ATOM   2830 C  CD1 . TYR B 2 32  ? 129.476 116.748 93.038  1.00 58.94  ? 32  TYR B CD1 1 
ATOM   2831 C  CD2 . TYR B 2 32  ? 129.961 118.585 91.605  1.00 58.94  ? 32  TYR B CD2 1 
ATOM   2832 C  CE1 . TYR B 2 32  ? 130.645 116.128 92.647  1.00 58.94  ? 32  TYR B CE1 1 
ATOM   2833 C  CE2 . TYR B 2 32  ? 131.134 117.972 91.208  1.00 58.94  ? 32  TYR B CE2 1 
ATOM   2834 C  CZ  . TYR B 2 32  ? 131.469 116.744 91.732  1.00 58.94  ? 32  TYR B CZ  1 
ATOM   2835 O  OH  . TYR B 2 32  ? 132.634 116.127 91.342  1.00 58.94  ? 32  TYR B OH  1 
ATOM   2836 N  N   . ASN B 2 33  ? 124.656 118.735 93.607  1.00 58.91  ? 33  ASN B N   1 
ATOM   2837 C  CA  . ASN B 2 33  ? 123.562 119.604 94.038  1.00 58.91  ? 33  ASN B CA  1 
ATOM   2838 C  C   . ASN B 2 33  ? 124.077 120.646 95.033  1.00 58.91  ? 33  ASN B C   1 
ATOM   2839 O  O   . ASN B 2 33  ? 123.612 120.762 96.166  1.00 58.91  ? 33  ASN B O   1 
ATOM   2840 C  CB  . ASN B 2 33  ? 122.435 118.773 94.638  1.00 58.91  ? 33  ASN B CB  1 
ATOM   2841 C  CG  . ASN B 2 33  ? 121.707 117.947 93.601  1.00 58.91  ? 33  ASN B CG  1 
ATOM   2842 O  OD1 . ASN B 2 33  ? 121.429 118.418 92.499  1.00 58.91  ? 33  ASN B OD1 1 
ATOM   2843 N  ND2 . ASN B 2 33  ? 121.393 116.705 93.949  1.00 58.91  ? 33  ASN B ND2 1 
ATOM   2844 N  N   . TYR B 2 34  ? 125.062 121.415 94.577  1.00 60.52  ? 34  TYR B N   1 
ATOM   2845 C  CA  . TYR B 2 34  ? 125.764 122.401 95.394  1.00 60.52  ? 34  TYR B CA  1 
ATOM   2846 C  C   . TYR B 2 34  ? 125.715 123.772 94.732  1.00 60.52  ? 34  TYR B C   1 
ATOM   2847 O  O   . TYR B 2 34  ? 126.726 124.464 94.596  1.00 60.52  ? 34  TYR B O   1 
ATOM   2848 C  CB  . TYR B 2 34  ? 127.208 121.972 95.637  1.00 60.52  ? 34  TYR B CB  1 
ATOM   2849 C  CG  . TYR B 2 34  ? 127.358 120.841 96.628  1.00 60.52  ? 34  TYR B CG  1 
ATOM   2850 C  CD1 . TYR B 2 34  ? 126.400 120.618 97.607  1.00 60.52  ? 34  TYR B CD1 1 
ATOM   2851 C  CD2 . TYR B 2 34  ? 128.457 119.994 96.584  1.00 60.52  ? 34  TYR B CD2 1 
ATOM   2852 C  CE1 . TYR B 2 34  ? 126.532 119.585 98.514  1.00 60.52  ? 34  TYR B CE1 1 
ATOM   2853 C  CE2 . TYR B 2 34  ? 128.598 118.959 97.487  1.00 60.52  ? 34  TYR B CE2 1 
ATOM   2854 C  CZ  . TYR B 2 34  ? 127.632 118.760 98.450  1.00 60.52  ? 34  TYR B CZ  1 
ATOM   2855 O  OH  . TYR B 2 34  ? 127.765 117.731 99.353  1.00 60.52  ? 34  TYR B OH  1 
ATOM   2856 N  N   . VAL B 2 35  ? 124.522 124.180 94.307  1.00 64.61  ? 35  VAL B N   1 
ATOM   2857 C  CA  . VAL B 2 35  ? 124.308 125.456 93.632  1.00 64.61  ? 35  VAL B CA  1 
ATOM   2858 C  C   . VAL B 2 35  ? 123.637 126.411 94.607  1.00 64.61  ? 35  VAL B C   1 
ATOM   2859 O  O   . VAL B 2 35  ? 122.614 126.072 95.215  1.00 64.61  ? 35  VAL B O   1 
ATOM   2860 C  CB  . VAL B 2 35  ? 123.463 125.288 92.359  1.00 64.61  ? 35  VAL B CB  1 
ATOM   2861 C  CG1 . VAL B 2 35  ? 123.380 126.604 91.604  1.00 64.61  ? 35  VAL B CG1 1 
ATOM   2862 C  CG2 . VAL B 2 35  ? 124.046 124.196 91.477  1.00 64.61  ? 35  VAL B CG2 1 
ATOM   2863 N  N   . SER B 2 36  ? 124.211 127.602 94.753  1.00 66.51  ? 36  SER B N   1 
ATOM   2864 C  CA  . SER B 2 36  ? 123.704 128.621 95.657  1.00 66.51  ? 36  SER B CA  1 
ATOM   2865 C  C   . SER B 2 36  ? 123.382 129.897 94.888  1.00 66.51  ? 36  SER B C   1 
ATOM   2866 O  O   . SER B 2 36  ? 123.854 130.114 93.769  1.00 66.51  ? 36  SER B O   1 
ATOM   2867 C  CB  . SER B 2 36  ? 124.711 128.925 96.774  1.00 66.51  ? 36  SER B CB  1 
ATOM   2868 O  OG  . SER B 2 36  ? 124.668 127.931 97.782  1.00 66.51  ? 36  SER B OG  1 
ATOM   2869 N  N   . TRP B 2 37  ? 122.569 130.745 95.514  1.00 68.55  ? 37  TRP B N   1 
ATOM   2870 C  CA  . TRP B 2 37  ? 122.112 131.998 94.927  1.00 68.55  ? 37  TRP B CA  1 
ATOM   2871 C  C   . TRP B 2 37  ? 122.333 133.132 95.915  1.00 68.55  ? 37  TRP B C   1 
ATOM   2872 O  O   . TRP B 2 37  ? 121.981 133.008 97.094  1.00 68.55  ? 37  TRP B O   1 
ATOM   2873 C  CB  . TRP B 2 37  ? 120.633 131.918 94.552  1.00 68.55  ? 37  TRP B CB  1 
ATOM   2874 C  CG  . TRP B 2 37  ? 120.327 130.981 93.431  1.00 68.55  ? 37  TRP B CG  1 
ATOM   2875 C  CD1 . TRP B 2 37  ? 119.909 129.688 93.536  1.00 68.55  ? 37  TRP B CD1 1 
ATOM   2876 C  CD2 . TRP B 2 37  ? 120.375 131.275 92.030  1.00 68.55  ? 37  TRP B CD2 1 
ATOM   2877 N  NE1 . TRP B 2 37  ? 119.712 129.152 92.287  1.00 68.55  ? 37  TRP B NE1 1 
ATOM   2878 C  CE2 . TRP B 2 37  ? 119.990 130.107 91.345  1.00 68.55  ? 37  TRP B CE2 1 
ATOM   2879 C  CE3 . TRP B 2 37  ? 120.715 132.410 91.289  1.00 68.55  ? 37  TRP B CE3 1 
ATOM   2880 C  CZ2 . TRP B 2 37  ? 119.935 130.042 89.956  1.00 68.55  ? 37  TRP B CZ2 1 
ATOM   2881 C  CZ3 . TRP B 2 37  ? 120.658 132.344 89.911  1.00 68.55  ? 37  TRP B CZ3 1 
ATOM   2882 C  CH2 . TRP B 2 37  ? 120.273 131.168 89.258  1.00 68.55  ? 37  TRP B CH2 1 
ATOM   2883 N  N   . TYR B 2 38  ? 122.881 134.243 95.424  1.00 71.17  ? 38  TYR B N   1 
ATOM   2884 C  CA  . TYR B 2 38  ? 123.188 135.403 96.247  1.00 71.17  ? 38  TYR B CA  1 
ATOM   2885 C  C   . TYR B 2 38  ? 122.539 136.650 95.661  1.00 71.17  ? 38  TYR B C   1 
ATOM   2886 O  O   . TYR B 2 38  ? 122.367 136.765 94.445  1.00 71.17  ? 38  TYR B O   1 
ATOM   2887 C  CB  . TYR B 2 38  ? 124.703 135.627 96.357  1.00 71.17  ? 38  TYR B CB  1 
ATOM   2888 C  CG  . TYR B 2 38  ? 125.457 134.462 96.949  1.00 71.17  ? 38  TYR B CG  1 
ATOM   2889 C  CD1 . TYR B 2 38  ? 125.779 133.358 96.175  1.00 71.17  ? 38  TYR B CD1 1 
ATOM   2890 C  CD2 . TYR B 2 38  ? 125.852 134.466 98.280  1.00 71.17  ? 38  TYR B CD2 1 
ATOM   2891 C  CE1 . TYR B 2 38  ? 126.465 132.293 96.707  1.00 71.17  ? 38  TYR B CE1 1 
ATOM   2892 C  CE2 . TYR B 2 38  ? 126.543 133.400 98.821  1.00 71.17  ? 38  TYR B CE2 1 
ATOM   2893 C  CZ  . TYR B 2 38  ? 126.846 132.315 98.026  1.00 71.17  ? 38  TYR B CZ  1 
ATOM   2894 O  OH  . TYR B 2 38  ? 127.531 131.240 98.541  1.00 71.17  ? 38  TYR B OH  1 
ATOM   2895 N  N   . GLN B 2 39  ? 122.183 137.585 96.540  1.00 72.64  ? 39  GLN B N   1 
ATOM   2896 C  CA  . GLN B 2 39  ? 121.691 138.898 96.144  1.00 72.64  ? 39  GLN B CA  1 
ATOM   2897 C  C   . GLN B 2 39  ? 122.566 139.972 96.774  1.00 72.64  ? 39  GLN B C   1 
ATOM   2898 O  O   . GLN B 2 39  ? 122.986 139.847 97.929  1.00 72.64  ? 39  GLN B O   1 
ATOM   2899 C  CB  . GLN B 2 39  ? 120.224 139.100 96.548  1.00 72.64  ? 39  GLN B CB  1 
ATOM   2900 C  CG  . GLN B 2 39  ? 119.971 139.118 98.046  1.00 72.64  ? 39  GLN B CG  1 
ATOM   2901 C  CD  . GLN B 2 39  ? 118.504 139.292 98.385  1.00 72.64  ? 39  GLN B CD  1 
ATOM   2902 O  OE1 . GLN B 2 39  ? 117.667 139.465 97.499  1.00 72.64  ? 39  GLN B OE1 1 
ATOM   2903 N  NE2 . GLN B 2 39  ? 118.184 139.246 99.673  1.00 72.64  ? 39  GLN B NE2 1 
ATOM   2904 N  N   . GLN B 2 40  ? 122.853 141.021 96.006  1.00 71.55  ? 40  GLN B N   1 
ATOM   2905 C  CA  . GLN B 2 40  ? 123.736 142.093 96.446  1.00 71.55  ? 40  GLN B CA  1 
ATOM   2906 C  C   . GLN B 2 40  ? 123.114 143.434 96.092  1.00 71.55  ? 40  GLN B C   1 
ATOM   2907 O  O   . GLN B 2 40  ? 122.646 143.628 94.964  1.00 71.55  ? 40  GLN B O   1 
ATOM   2908 C  CB  . GLN B 2 40  ? 125.122 141.963 95.811  1.00 71.55  ? 40  GLN B CB  1 
ATOM   2909 C  CG  . GLN B 2 40  ? 126.079 143.078 96.188  1.00 71.55  ? 40  GLN B CG  1 
ATOM   2910 C  CD  . GLN B 2 40  ? 127.389 143.001 95.434  1.00 71.55  ? 40  GLN B CD  1 
ATOM   2911 O  OE1 . GLN B 2 40  ? 128.383 143.606 95.833  1.00 71.55  ? 40  GLN B OE1 1 
ATOM   2912 N  NE2 . GLN B 2 40  ? 127.398 142.254 94.337  1.00 71.55  ? 40  GLN B NE2 1 
ATOM   2913 N  N   . HIS B 2 41  ? 123.107 144.350 97.054  1.00 75.74  ? 41  HIS B N   1 
ATOM   2914 C  CA  . HIS B 2 41  ? 122.670 145.713 96.821  1.00 75.74  ? 41  HIS B CA  1 
ATOM   2915 C  C   . HIS B 2 41  ? 123.879 146.637 96.719  1.00 75.74  ? 41  HIS B C   1 
ATOM   2916 O  O   . HIS B 2 41  ? 124.928 146.367 97.309  1.00 75.74  ? 41  HIS B O   1 
ATOM   2917 C  CB  . HIS B 2 41  ? 121.750 146.171 97.948  1.00 75.74  ? 41  HIS B CB  1 
ATOM   2918 C  CG  . HIS B 2 41  ? 120.355 145.644 97.839  1.00 75.74  ? 41  HIS B CG  1 
ATOM   2919 N  ND1 . HIS B 2 41  ? 119.833 144.729 98.728  1.00 75.74  ? 41  HIS B ND1 1 
ATOM   2920 C  CD2 . HIS B 2 41  ? 119.373 145.899 96.943  1.00 75.74  ? 41  HIS B CD2 1 
ATOM   2921 C  CE1 . HIS B 2 41  ? 118.589 144.446 98.387  1.00 75.74  ? 41  HIS B CE1 1 
ATOM   2922 N  NE2 . HIS B 2 41  ? 118.286 145.143 97.306  1.00 75.74  ? 41  HIS B NE2 1 
ATOM   2923 N  N   . PRO B 2 42  ? 123.764 147.730 95.957  1.00 74.99  ? 42  PRO B N   1 
ATOM   2924 C  CA  . PRO B 2 42  ? 124.893 148.662 95.832  1.00 74.99  ? 42  PRO B CA  1 
ATOM   2925 C  C   . PRO B 2 42  ? 125.362 149.191 97.177  1.00 74.99  ? 42  PRO B C   1 
ATOM   2926 O  O   . PRO B 2 42  ? 124.568 149.728 97.956  1.00 74.99  ? 42  PRO B O   1 
ATOM   2927 C  CB  . PRO B 2 42  ? 124.325 149.784 94.954  1.00 74.99  ? 42  PRO B CB  1 
ATOM   2928 C  CG  . PRO B 2 42  ? 123.230 149.136 94.181  1.00 74.99  ? 42  PRO B CG  1 
ATOM   2929 C  CD  . PRO B 2 42  ? 122.628 148.119 95.104  1.00 74.99  ? 42  PRO B CD  1 
ATOM   2930 N  N   . GLY B 2 43  ? 126.653 149.039 97.458  1.00 77.30  ? 43  GLY B N   1 
ATOM   2931 C  CA  . GLY B 2 43  ? 127.201 149.439 98.736  1.00 77.30  ? 43  GLY B CA  1 
ATOM   2932 C  C   . GLY B 2 43  ? 126.989 148.455 99.862  1.00 77.30  ? 43  GLY B C   1 
ATOM   2933 O  O   . GLY B 2 43  ? 127.282 148.786 101.016 1.00 77.30  ? 43  GLY B O   1 
ATOM   2934 N  N   . LYS B 2 44  ? 126.491 147.255 99.569  1.00 75.98  ? 44  LYS B N   1 
ATOM   2935 C  CA  . LYS B 2 44  ? 126.222 146.249 100.583 1.00 75.98  ? 44  LYS B CA  1 
ATOM   2936 C  C   . LYS B 2 44  ? 126.878 144.932 100.194 1.00 75.98  ? 44  LYS B C   1 
ATOM   2937 O  O   . LYS B 2 44  ? 126.984 144.597 99.012  1.00 75.98  ? 44  LYS B O   1 
ATOM   2938 C  CB  . LYS B 2 44  ? 124.715 146.036 100.784 1.00 75.98  ? 44  LYS B CB  1 
ATOM   2939 C  CG  . LYS B 2 44  ? 123.957 147.288 101.193 1.00 75.98  ? 44  LYS B CG  1 
ATOM   2940 C  CD  . LYS B 2 44  ? 122.558 146.949 101.680 1.00 75.98  ? 44  LYS B CD  1 
ATOM   2941 C  CE  . LYS B 2 44  ? 121.724 148.203 101.884 1.00 75.98  ? 44  LYS B CE  1 
ATOM   2942 N  NZ  . LYS B 2 44  ? 120.297 147.880 102.156 1.00 75.98  ? 44  LYS B NZ  1 
ATOM   2943 N  N   . ALA B 2 45  ? 127.318 144.191 101.207 1.00 70.50  ? 45  ALA B N   1 
ATOM   2944 C  CA  . ALA B 2 45  ? 127.942 142.901 100.973 1.00 70.50  ? 45  ALA B CA  1 
ATOM   2945 C  C   . ALA B 2 45  ? 126.905 141.888 100.490 1.00 70.50  ? 45  ALA B C   1 
ATOM   2946 O  O   . ALA B 2 45  ? 125.724 141.983 100.836 1.00 70.50  ? 45  ALA B O   1 
ATOM   2947 C  CB  . ALA B 2 45  ? 128.610 142.392 102.246 1.00 70.50  ? 45  ALA B CB  1 
ATOM   2948 N  N   . PRO B 2 46  ? 127.319 140.918 99.675  1.00 64.86  ? 46  PRO B N   1 
ATOM   2949 C  CA  . PRO B 2 46  ? 126.373 139.901 99.201  1.00 64.86  ? 46  PRO B CA  1 
ATOM   2950 C  C   . PRO B 2 46  ? 125.785 139.105 100.356 1.00 64.86  ? 46  PRO B C   1 
ATOM   2951 O  O   . PRO B 2 46  ? 126.430 138.883 101.382 1.00 64.86  ? 46  PRO B O   1 
ATOM   2952 C  CB  . PRO B 2 46  ? 127.220 139.008 98.287  1.00 64.86  ? 46  PRO B CB  1 
ATOM   2953 C  CG  . PRO B 2 46  ? 128.464 139.754 98.004  1.00 64.86  ? 46  PRO B CG  1 
ATOM   2954 C  CD  . PRO B 2 46  ? 128.623 140.859 98.992  1.00 64.86  ? 46  PRO B CD  1 
ATOM   2955 N  N   . LYS B 2 47  ? 124.540 138.677 100.175 1.00 68.39  ? 47  LYS B N   1 
ATOM   2956 C  CA  . LYS B 2 47  ? 123.814 137.904 101.173 1.00 68.39  ? 47  LYS B CA  1 
ATOM   2957 C  C   . LYS B 2 47  ? 123.415 136.568 100.567 1.00 68.39  ? 47  LYS B C   1 
ATOM   2958 O  O   . LYS B 2 47  ? 122.965 136.513 99.417  1.00 68.39  ? 47  LYS B O   1 
ATOM   2959 C  CB  . LYS B 2 47  ? 122.578 138.665 101.662 1.00 68.39  ? 47  LYS B CB  1 
ATOM   2960 C  CG  . LYS B 2 47  ? 121.666 137.863 102.574 1.00 68.39  ? 47  LYS B CG  1 
ATOM   2961 C  CD  . LYS B 2 47  ? 120.380 138.619 102.870 1.00 68.39  ? 47  LYS B CD  1 
ATOM   2962 C  CE  . LYS B 2 47  ? 119.414 137.770 103.680 1.00 68.39  ? 47  LYS B CE  1 
ATOM   2963 N  NZ  . LYS B 2 47  ? 118.109 138.457 103.888 1.00 68.39  ? 47  LYS B NZ  1 
ATOM   2964 N  N   . LEU B 2 48  ? 123.579 135.495 101.338 1.00 67.84  ? 48  LEU B N   1 
ATOM   2965 C  CA  . LEU B 2 48  ? 123.252 134.156 100.860 1.00 67.84  ? 48  LEU B CA  1 
ATOM   2966 C  C   . LEU B 2 48  ? 121.738 134.011 100.781 1.00 67.84  ? 48  LEU B C   1 
ATOM   2967 O  O   . LEU B 2 48  ? 121.082 133.698 101.780 1.00 67.84  ? 48  LEU B O   1 
ATOM   2968 C  CB  . LEU B 2 48  ? 123.861 133.102 101.779 1.00 67.84  ? 48  LEU B CB  1 
ATOM   2969 C  CG  . LEU B 2 48  ? 123.487 131.645 101.497 1.00 67.84  ? 48  LEU B CG  1 
ATOM   2970 C  CD1 . LEU B 2 48  ? 124.008 131.211 100.137 1.00 67.84  ? 48  LEU B CD1 1 
ATOM   2971 C  CD2 . LEU B 2 48  ? 124.015 130.732 102.593 1.00 67.84  ? 48  LEU B CD2 1 
ATOM   2972 N  N   . MET B 2 49  ? 121.180 134.255 99.596  1.00 68.37  ? 49  MET B N   1 
ATOM   2973 C  CA  . MET B 2 49  ? 119.735 134.172 99.423  1.00 68.37  ? 49  MET B CA  1 
ATOM   2974 C  C   . MET B 2 49  ? 119.245 132.730 99.495  1.00 68.37  ? 49  MET B C   1 
ATOM   2975 O  O   . MET B 2 49  ? 118.265 132.435 100.187 1.00 68.37  ? 49  MET B O   1 
ATOM   2976 C  CB  . MET B 2 49  ? 119.329 134.814 98.096  1.00 68.37  ? 49  MET B CB  1 
ATOM   2977 N  N   . ILE B 2 50  ? 119.910 131.819 98.788  1.00 67.84  ? 50  ILE B N   1 
ATOM   2978 C  CA  . ILE B 2 50  ? 119.502 130.418 98.740  1.00 67.84  ? 50  ILE B CA  1 
ATOM   2979 C  C   . ILE B 2 50  ? 120.743 129.541 98.821  1.00 67.84  ? 50  ILE B C   1 
ATOM   2980 O  O   . ILE B 2 50  ? 121.722 129.778 98.106  1.00 67.84  ? 50  ILE B O   1 
ATOM   2981 C  CB  . ILE B 2 50  ? 118.697 130.103 97.463  1.00 67.84  ? 50  ILE B CB  1 
ATOM   2982 C  CG1 . ILE B 2 50  ? 117.271 130.642 97.582  1.00 67.84  ? 50  ILE B CG1 1 
ATOM   2983 C  CG2 . ILE B 2 50  ? 118.676 128.609 97.190  1.00 67.84  ? 50  ILE B CG2 1 
ATOM   2984 C  CD1 . ILE B 2 50  ? 116.408 129.873 98.553  1.00 67.84  ? 50  ILE B CD1 1 
ATOM   2985 N  N   . TYR B 2 51  ? 120.695 128.520 99.674  1.00 68.74  ? 51  TYR B N   1 
ATOM   2986 C  CA  . TYR B 2 51  ? 121.772 127.554 99.816  1.00 68.74  ? 51  TYR B CA  1 
ATOM   2987 C  C   . TYR B 2 51  ? 121.229 126.148 99.597  1.00 68.74  ? 51  TYR B C   1 
ATOM   2988 O  O   . TYR B 2 51  ? 120.047 125.877 99.820  1.00 68.74  ? 51  TYR B O   1 
ATOM   2989 C  CB  . TYR B 2 51  ? 122.435 127.647 101.196 1.00 68.74  ? 51  TYR B CB  1 
ATOM   2990 C  CG  . TYR B 2 51  ? 121.697 126.898 102.283 1.00 68.74  ? 51  TYR B CG  1 
ATOM   2991 C  CD1 . TYR B 2 51  ? 120.467 127.341 102.747 1.00 68.74  ? 51  TYR B CD1 1 
ATOM   2992 C  CD2 . TYR B 2 51  ? 122.233 125.748 102.844 1.00 68.74  ? 51  TYR B CD2 1 
ATOM   2993 C  CE1 . TYR B 2 51  ? 119.790 126.658 103.740 1.00 68.74  ? 51  TYR B CE1 1 
ATOM   2994 C  CE2 . TYR B 2 51  ? 121.565 125.059 103.837 1.00 68.74  ? 51  TYR B CE2 1 
ATOM   2995 C  CZ  . TYR B 2 51  ? 120.344 125.517 104.281 1.00 68.74  ? 51  TYR B CZ  1 
ATOM   2996 O  OH  . TYR B 2 51  ? 119.676 124.833 105.271 1.00 68.74  ? 51  TYR B OH  1 
ATOM   2997 N  N   . ASP B 2 52  ? 122.114 125.255 99.151  1.00 66.62  ? 52  ASP B N   1 
ATOM   2998 C  CA  . ASP B 2 52  ? 121.771 123.858 98.884  1.00 66.62  ? 52  ASP B CA  1 
ATOM   2999 C  C   . ASP B 2 52  ? 120.624 123.751 97.880  1.00 66.62  ? 52  ASP B C   1 
ATOM   3000 O  O   . ASP B 2 52  ? 119.588 123.135 98.141  1.00 66.62  ? 52  ASP B O   1 
ATOM   3001 C  CB  . ASP B 2 52  ? 121.438 123.117 100.181 1.00 66.62  ? 52  ASP B CB  1 
ATOM   3002 C  CG  . ASP B 2 52  ? 122.668 122.540 100.854 1.00 66.62  ? 52  ASP B CG  1 
ATOM   3003 O  OD1 . ASP B 2 52  ? 123.704 122.389 100.172 1.00 66.62  ? 52  ASP B OD1 1 
ATOM   3004 O  OD2 . ASP B 2 52  ? 122.600 122.239 102.064 1.00 66.62  ? 52  ASP B OD2 1 
ATOM   3005 N  N   . VAL B 2 53  ? 120.820 124.380 96.722  1.00 65.43  ? 53  VAL B N   1 
ATOM   3006 C  CA  . VAL B 2 53  ? 119.898 124.316 95.589  1.00 65.43  ? 53  VAL B CA  1 
ATOM   3007 C  C   . VAL B 2 53  ? 118.536 124.903 95.945  1.00 65.43  ? 53  VAL B C   1 
ATOM   3008 O  O   . VAL B 2 53  ? 118.136 125.935 95.394  1.00 65.43  ? 53  VAL B O   1 
ATOM   3009 C  CB  . VAL B 2 53  ? 119.755 122.873 95.070  1.00 65.43  ? 53  VAL B CB  1 
ATOM   3010 C  CG1 . VAL B 2 53  ? 118.629 122.782 94.053  1.00 65.43  ? 53  VAL B CG1 1 
ATOM   3011 C  CG2 . VAL B 2 53  ? 121.064 122.402 94.462  1.00 65.43  ? 53  VAL B CG2 1 
ATOM   3012 N  N   . SER B 2 54  ? 117.812 124.258 96.857  1.00 66.82  ? 54  SER B N   1 
ATOM   3013 C  CA  . SER B 2 54  ? 116.428 124.630 97.145  1.00 66.82  ? 54  SER B CA  1 
ATOM   3014 C  C   . SER B 2 54  ? 116.171 124.650 98.649  1.00 66.82  ? 54  SER B C   1 
ATOM   3015 O  O   . SER B 2 54  ? 115.171 124.125 99.139  1.00 66.82  ? 54  SER B O   1 
ATOM   3016 C  CB  . SER B 2 54  ? 115.459 123.685 96.439  1.00 66.82  ? 54  SER B CB  1 
ATOM   3017 O  OG  . SER B 2 54  ? 115.558 122.372 96.962  1.00 66.82  ? 54  SER B OG  1 
ATOM   3018 N  N   . LYS B 2 55  ? 117.078 125.266 99.404  1.00 67.78  ? 55  LYS B N   1 
ATOM   3019 C  CA  . LYS B 2 55  ? 116.907 125.427 100.840 1.00 67.78  ? 55  LYS B CA  1 
ATOM   3020 C  C   . LYS B 2 55  ? 117.153 126.879 101.224 1.00 67.78  ? 55  LYS B C   1 
ATOM   3021 O  O   . LYS B 2 55  ? 117.928 127.588 100.576 1.00 67.78  ? 55  LYS B O   1 
ATOM   3022 C  CB  . LYS B 2 55  ? 117.842 124.502 101.632 1.00 67.78  ? 55  LYS B CB  1 
ATOM   3023 C  CG  . LYS B 2 55  ? 117.519 123.024 101.480 1.00 67.78  ? 55  LYS B CG  1 
ATOM   3024 C  CD  . LYS B 2 55  ? 118.230 122.190 102.533 1.00 67.78  ? 55  LYS B CD  1 
ATOM   3025 C  CE  . LYS B 2 55  ? 118.444 120.763 102.054 1.00 67.78  ? 55  LYS B CE  1 
ATOM   3026 N  NZ  . LYS B 2 55  ? 119.735 120.202 102.539 1.00 67.78  ? 55  LYS B NZ  1 
ATOM   3027 N  N   . ARG B 2 56  ? 116.477 127.318 102.291 1.00 71.17  ? 56  ARG B N   1 
ATOM   3028 C  CA  . ARG B 2 56  ? 116.498 128.708 102.712 1.00 71.17  ? 56  ARG B CA  1 
ATOM   3029 C  C   . ARG B 2 56  ? 117.267 128.876 104.017 1.00 71.17  ? 56  ARG B C   1 
ATOM   3030 O  O   . ARG B 2 56  ? 117.130 128.052 104.928 1.00 71.17  ? 56  ARG B O   1 
ATOM   3031 C  CB  . ARG B 2 56  ? 115.074 129.241 102.902 1.00 71.17  ? 56  ARG B CB  1 
ATOM   3032 C  CG  . ARG B 2 56  ? 114.336 129.529 101.609 1.00 71.17  ? 56  ARG B CG  1 
ATOM   3033 C  CD  . ARG B 2 56  ? 113.080 130.338 101.871 1.00 71.17  ? 56  ARG B CD  1 
ATOM   3034 N  NE  . ARG B 2 56  ? 112.084 129.563 102.600 1.00 71.17  ? 56  ARG B NE  1 
ATOM   3035 C  CZ  . ARG B 2 56  ? 111.224 128.727 102.035 1.00 71.17  ? 56  ARG B CZ  1 
ATOM   3036 N  NH1 . ARG B 2 56  ? 111.211 128.530 100.726 1.00 71.17  ? 56  ARG B NH1 1 
ATOM   3037 N  NH2 . ARG B 2 56  ? 110.357 128.071 102.801 1.00 71.17  ? 56  ARG B NH2 1 
ATOM   3038 N  N   . PRO B 2 57  ? 118.078 129.928 104.137 1.00 73.90  ? 57  PRO B N   1 
ATOM   3039 C  CA  . PRO B 2 57  ? 118.768 130.191 105.407 1.00 73.90  ? 57  PRO B CA  1 
ATOM   3040 C  C   . PRO B 2 57  ? 117.825 130.732 106.470 1.00 73.90  ? 57  PRO B C   1 
ATOM   3041 O  O   . PRO B 2 57  ? 116.609 130.788 106.260 1.00 73.90  ? 57  PRO B O   1 
ATOM   3042 C  CB  . PRO B 2 57  ? 119.833 131.229 105.026 1.00 73.90  ? 57  PRO B CB  1 
ATOM   3043 C  CG  . PRO B 2 57  ? 119.928 131.171 103.529 1.00 73.90  ? 57  PRO B CG  1 
ATOM   3044 C  CD  . PRO B 2 57  ? 118.560 130.804 103.059 1.00 73.90  ? 57  PRO B CD  1 
ATOM   3045 N  N   . SER B 2 58  ? 118.377 131.123 107.620 1.00 78.74  ? 58  SER B N   1 
ATOM   3046 C  CA  . SER B 2 58  ? 117.582 131.700 108.697 1.00 78.74  ? 58  SER B CA  1 
ATOM   3047 C  C   . SER B 2 58  ? 116.869 132.960 108.224 1.00 78.74  ? 58  SER B C   1 
ATOM   3048 O  O   . SER B 2 58  ? 117.514 133.957 107.885 1.00 78.74  ? 58  SER B O   1 
ATOM   3049 C  CB  . SER B 2 58  ? 118.464 132.009 109.909 1.00 78.74  ? 58  SER B CB  1 
ATOM   3050 O  OG  . SER B 2 58  ? 117.678 132.340 111.041 1.00 78.74  ? 58  SER B OG  1 
ATOM   3051 N  N   . GLY B 2 59  ? 115.543 132.924 108.199 1.00 77.25  ? 59  GLY B N   1 
ATOM   3052 C  CA  . GLY B 2 59  ? 114.766 134.031 107.664 1.00 77.25  ? 59  GLY B CA  1 
ATOM   3053 C  C   . GLY B 2 59  ? 114.437 133.800 106.203 1.00 77.25  ? 59  GLY B C   1 
ATOM   3054 O  O   . GLY B 2 59  ? 114.009 132.708 105.827 1.00 77.25  ? 59  GLY B O   1 
ATOM   3055 N  N   . VAL B 2 60  ? 114.636 134.836 105.384 1.00 76.76  ? 60  VAL B N   1 
ATOM   3056 C  CA  . VAL B 2 60  ? 114.450 134.791 103.934 1.00 76.76  ? 60  VAL B CA  1 
ATOM   3057 C  C   . VAL B 2 60  ? 112.978 134.601 103.585 1.00 76.76  ? 60  VAL B C   1 
ATOM   3058 O  O   . VAL B 2 60  ? 112.353 133.611 103.978 1.00 76.76  ? 60  VAL B O   1 
ATOM   3059 C  CB  . VAL B 2 60  ? 115.316 133.693 103.287 1.00 76.76  ? 60  VAL B CB  1 
ATOM   3060 C  CG1 . VAL B 2 60  ? 114.983 133.557 101.810 1.00 76.76  ? 60  VAL B CG1 1 
ATOM   3061 C  CG2 . VAL B 2 60  ? 116.792 134.005 103.480 1.00 76.76  ? 60  VAL B CG2 1 
ATOM   3062 N  N   . SER B 2 61  ? 112.420 135.551 102.838 1.00 77.45  ? 61  SER B N   1 
ATOM   3063 C  CA  . SER B 2 61  ? 111.015 135.483 102.463 1.00 77.45  ? 61  SER B CA  1 
ATOM   3064 C  C   . SER B 2 61  ? 110.746 134.262 101.591 1.00 77.45  ? 61  SER B C   1 
ATOM   3065 O  O   . SER B 2 61  ? 111.607 133.806 100.834 1.00 77.45  ? 61  SER B O   1 
ATOM   3066 C  CB  . SER B 2 61  ? 110.598 136.756 101.726 1.00 77.45  ? 61  SER B CB  1 
ATOM   3067 O  OG  . SER B 2 61  ? 109.228 136.713 101.368 1.00 77.45  ? 61  SER B OG  1 
ATOM   3068 N  N   . ASN B 2 62  ? 109.527 133.729 101.710 1.00 76.74  ? 62  ASN B N   1 
ATOM   3069 C  CA  . ASN B 2 62  ? 109.150 132.526 100.975 1.00 76.74  ? 62  ASN B CA  1 
ATOM   3070 C  C   . ASN B 2 62  ? 109.116 132.752 99.468  1.00 76.74  ? 62  ASN B C   1 
ATOM   3071 O  O   . ASN B 2 62  ? 109.152 131.779 98.705  1.00 76.74  ? 62  ASN B O   1 
ATOM   3072 C  CB  . ASN B 2 62  ? 107.790 132.028 101.475 1.00 76.74  ? 62  ASN B CB  1 
ATOM   3073 C  CG  . ASN B 2 62  ? 107.241 130.886 100.643 1.00 76.74  ? 62  ASN B CG  1 
ATOM   3074 O  OD1 . ASN B 2 62  ? 107.836 129.811 100.574 1.00 76.74  ? 62  ASN B OD1 1 
ATOM   3075 N  ND2 . ASN B 2 62  ? 106.100 131.115 100.004 1.00 76.74  ? 62  ASN B ND2 1 
ATOM   3076 N  N   . ARG B 2 63  ? 109.070 134.011 99.020  1.00 80.47  ? 63  ARG B N   1 
ATOM   3077 C  CA  . ARG B 2 63  ? 108.993 134.302 97.592  1.00 80.47  ? 63  ARG B CA  1 
ATOM   3078 C  C   . ARG B 2 63  ? 110.177 133.740 96.814  1.00 80.47  ? 63  ARG B C   1 
ATOM   3079 O  O   . ARG B 2 63  ? 110.046 133.476 95.614  1.00 80.47  ? 63  ARG B O   1 
ATOM   3080 C  CB  . ARG B 2 63  ? 108.895 135.812 97.369  1.00 80.47  ? 63  ARG B CB  1 
ATOM   3081 N  N   . PHE B 2 64  ? 111.323 133.552 97.464  1.00 78.01  ? 64  PHE B N   1 
ATOM   3082 C  CA  . PHE B 2 64  ? 112.480 132.960 96.807  1.00 78.01  ? 64  PHE B CA  1 
ATOM   3083 C  C   . PHE B 2 64  ? 112.337 131.444 96.779  1.00 78.01  ? 64  PHE B C   1 
ATOM   3084 O  O   . PHE B 2 64  ? 112.148 130.813 97.824  1.00 78.01  ? 64  PHE B O   1 
ATOM   3085 C  CB  . PHE B 2 64  ? 113.766 133.350 97.537  1.00 78.01  ? 64  PHE B CB  1 
ATOM   3086 C  CG  . PHE B 2 64  ? 114.094 134.813 97.459  1.00 78.01  ? 64  PHE B CG  1 
ATOM   3087 C  CD1 . PHE B 2 64  ? 113.567 135.606 96.454  1.00 78.01  ? 64  PHE B CD1 1 
ATOM   3088 C  CD2 . PHE B 2 64  ? 114.932 135.396 98.395  1.00 78.01  ? 64  PHE B CD2 1 
ATOM   3089 C  CE1 . PHE B 2 64  ? 113.871 136.953 96.385  1.00 78.01  ? 64  PHE B CE1 1 
ATOM   3090 C  CE2 . PHE B 2 64  ? 115.239 136.741 98.331  1.00 78.01  ? 64  PHE B CE2 1 
ATOM   3091 C  CZ  . PHE B 2 64  ? 114.709 137.520 97.325  1.00 78.01  ? 64  PHE B CZ  1 
ATOM   3092 N  N   . SER B 2 65  ? 112.426 130.856 95.587  1.00 79.60  ? 65  SER B N   1 
ATOM   3093 C  CA  . SER B 2 65  ? 112.398 129.408 95.452  1.00 79.60  ? 65  SER B CA  1 
ATOM   3094 C  C   . SER B 2 65  ? 113.460 128.977 94.452  1.00 79.60  ? 65  SER B C   1 
ATOM   3095 O  O   . SER B 2 65  ? 113.843 129.742 93.565  1.00 79.60  ? 65  SER B O   1 
ATOM   3096 C  CB  . SER B 2 65  ? 111.017 128.904 95.010  1.00 79.60  ? 65  SER B CB  1 
ATOM   3097 O  OG  . SER B 2 65  ? 110.706 129.345 93.701  1.00 79.60  ? 65  SER B OG  1 
ATOM   3098 N  N   . GLY B 2 66  ? 113.928 127.737 94.599  1.00 73.52  ? 66  GLY B N   1 
ATOM   3099 C  CA  . GLY B 2 66  ? 114.963 127.215 93.738  1.00 73.52  ? 66  GLY B CA  1 
ATOM   3100 C  C   . GLY B 2 66  ? 114.569 125.878 93.143  1.00 73.52  ? 66  GLY B C   1 
ATOM   3101 O  O   . GLY B 2 66  ? 113.787 125.118 93.715  1.00 73.52  ? 66  GLY B O   1 
ATOM   3102 N  N   . SER B 2 67  ? 115.133 125.603 91.969  1.00 69.84  ? 67  SER B N   1 
ATOM   3103 C  CA  . SER B 2 67  ? 114.884 124.345 91.279  1.00 69.84  ? 67  SER B CA  1 
ATOM   3104 C  C   . SER B 2 67  ? 116.079 124.027 90.394  1.00 69.84  ? 67  SER B C   1 
ATOM   3105 O  O   . SER B 2 67  ? 116.886 124.902 90.070  1.00 69.84  ? 67  SER B O   1 
ATOM   3106 C  CB  . SER B 2 67  ? 113.595 124.402 90.452  1.00 69.84  ? 67  SER B CB  1 
ATOM   3107 O  OG  . SER B 2 67  ? 113.711 125.331 89.388  1.00 69.84  ? 67  SER B OG  1 
ATOM   3108 N  N   . LYS B 2 68  ? 116.179 122.759 90.004  1.00 64.09  ? 68  LYS B N   1 
ATOM   3109 C  CA  . LYS B 2 68  ? 117.282 122.295 89.178  1.00 64.09  ? 68  LYS B CA  1 
ATOM   3110 C  C   . LYS B 2 68  ? 116.746 121.385 88.082  1.00 64.09  ? 68  LYS B C   1 
ATOM   3111 O  O   . LYS B 2 68  ? 115.778 120.648 88.283  1.00 64.09  ? 68  LYS B O   1 
ATOM   3112 C  CB  . LYS B 2 68  ? 118.335 121.557 90.018  1.00 64.09  ? 68  LYS B CB  1 
ATOM   3113 C  CG  . LYS B 2 68  ? 119.564 121.121 89.239  1.00 64.09  ? 68  LYS B CG  1 
ATOM   3114 C  CD  . LYS B 2 68  ? 120.748 120.894 90.159  1.00 64.09  ? 68  LYS B CD  1 
ATOM   3115 C  CE  . LYS B 2 68  ? 122.052 120.928 89.386  1.00 64.09  ? 68  LYS B CE  1 
ATOM   3116 N  NZ  . LYS B 2 68  ? 122.284 119.670 88.628  1.00 64.09  ? 68  LYS B NZ  1 
ATOM   3117 N  N   . SER B 2 69  ? 117.386 121.450 86.917  1.00 63.77  ? 69  SER B N   1 
ATOM   3118 C  CA  . SER B 2 69  ? 117.027 120.597 85.788  1.00 63.77  ? 69  SER B CA  1 
ATOM   3119 C  C   . SER B 2 69  ? 118.240 120.487 84.882  1.00 63.77  ? 69  SER B C   1 
ATOM   3120 O  O   . SER B 2 69  ? 118.648 121.484 84.276  1.00 63.77  ? 69  SER B O   1 
ATOM   3121 C  CB  . SER B 2 69  ? 115.829 121.164 85.028  1.00 63.77  ? 69  SER B CB  1 
ATOM   3122 O  OG  . SER B 2 69  ? 115.503 120.351 83.915  1.00 63.77  ? 69  SER B OG  1 
ATOM   3123 N  N   . GLY B 2 70  ? 118.808 119.292 84.787  1.00 67.24  ? 70  GLY B N   1 
ATOM   3124 C  CA  . GLY B 2 70  ? 120.015 119.113 83.997  1.00 67.24  ? 70  GLY B CA  1 
ATOM   3125 C  C   . GLY B 2 70  ? 121.138 119.970 84.545  1.00 67.24  ? 70  GLY B C   1 
ATOM   3126 O  O   . GLY B 2 70  ? 121.450 119.939 85.742  1.00 67.24  ? 70  GLY B O   1 
ATOM   3127 N  N   . ASN B 2 71  ? 121.760 120.752 83.666  1.00 66.78  ? 71  ASN B N   1 
ATOM   3128 C  CA  . ASN B 2 71  ? 122.805 121.688 84.050  1.00 66.78  ? 71  ASN B CA  1 
ATOM   3129 C  C   . ASN B 2 71  ? 122.265 123.087 84.318  1.00 66.78  ? 71  ASN B C   1 
ATOM   3130 O  O   . ASN B 2 71  ? 123.038 124.050 84.315  1.00 66.78  ? 71  ASN B O   1 
ATOM   3131 C  CB  . ASN B 2 71  ? 123.884 121.745 82.967  1.00 66.78  ? 71  ASN B CB  1 
ATOM   3132 C  CG  . ASN B 2 71  ? 124.544 120.403 82.735  1.00 66.78  ? 71  ASN B CG  1 
ATOM   3133 O  OD1 . ASN B 2 71  ? 125.294 119.914 83.578  1.00 66.78  ? 71  ASN B OD1 1 
ATOM   3134 N  ND2 . ASN B 2 71  ? 124.267 119.798 81.587  1.00 66.78  ? 71  ASN B ND2 1 
ATOM   3135 N  N   . THR B 2 72  ? 120.961 123.220 84.549  1.00 67.05  ? 72  THR B N   1 
ATOM   3136 C  CA  . THR B 2 72  ? 120.310 124.515 84.710  1.00 67.05  ? 72  THR B CA  1 
ATOM   3137 C  C   . THR B 2 72  ? 119.803 124.656 86.139  1.00 67.05  ? 72  THR B C   1 
ATOM   3138 O  O   . THR B 2 72  ? 119.101 123.773 86.644  1.00 67.05  ? 72  THR B O   1 
ATOM   3139 C  CB  . THR B 2 72  ? 119.157 124.671 83.718  1.00 67.05  ? 72  THR B CB  1 
ATOM   3140 O  OG1 . THR B 2 72  ? 119.674 124.698 82.382  1.00 67.05  ? 72  THR B OG1 1 
ATOM   3141 C  CG2 . THR B 2 72  ? 118.392 125.958 83.986  1.00 67.05  ? 72  THR B CG2 1 
ATOM   3142 N  N   . ALA B 2 73  ? 120.163 125.760 86.786  1.00 69.18  ? 73  ALA B N   1 
ATOM   3143 C  CA  . ALA B 2 73  ? 119.627 126.122 88.090  1.00 69.18  ? 73  ALA B CA  1 
ATOM   3144 C  C   . ALA B 2 73  ? 118.713 127.328 87.926  1.00 69.18  ? 73  ALA B C   1 
ATOM   3145 O  O   . ALA B 2 73  ? 119.106 128.332 87.323  1.00 69.18  ? 73  ALA B O   1 
ATOM   3146 C  CB  . ALA B 2 73  ? 120.750 126.432 89.079  1.00 69.18  ? 73  ALA B CB  1 
ATOM   3147 N  N   . SER B 2 74  ? 117.496 127.227 88.456  1.00 71.79  ? 74  SER B N   1 
ATOM   3148 C  CA  . SER B 2 74  ? 116.474 128.247 88.276  1.00 71.79  ? 74  SER B CA  1 
ATOM   3149 C  C   . SER B 2 74  ? 116.072 128.821 89.625  1.00 71.79  ? 74  SER B C   1 
ATOM   3150 O  O   . SER B 2 74  ? 115.794 128.071 90.568  1.00 71.79  ? 74  SER B O   1 
ATOM   3151 C  CB  . SER B 2 74  ? 115.248 127.672 87.561  1.00 71.79  ? 74  SER B CB  1 
ATOM   3152 O  OG  . SER B 2 74  ? 115.623 126.979 86.384  1.00 71.79  ? 74  SER B OG  1 
ATOM   3153 N  N   . LEU B 2 75  ? 116.041 130.148 89.712  1.00 73.80  ? 75  LEU B N   1 
ATOM   3154 C  CA  . LEU B 2 75  ? 115.528 130.858 90.874  1.00 73.80  ? 75  LEU B CA  1 
ATOM   3155 C  C   . LEU B 2 75  ? 114.238 131.561 90.483  1.00 73.80  ? 75  LEU B C   1 
ATOM   3156 O  O   . LEU B 2 75  ? 114.212 132.326 89.515  1.00 73.80  ? 75  LEU B O   1 
ATOM   3157 C  CB  . LEU B 2 75  ? 116.547 131.869 91.406  1.00 73.80  ? 75  LEU B CB  1 
ATOM   3158 C  CG  . LEU B 2 75  ? 116.162 132.655 92.664  1.00 73.80  ? 75  LEU B CG  1 
ATOM   3159 C  CD1 . LEU B 2 75  ? 117.371 132.881 93.543  1.00 73.80  ? 75  LEU B CD1 1 
ATOM   3160 C  CD2 . LEU B 2 75  ? 115.535 133.993 92.304  1.00 73.80  ? 75  LEU B CD2 1 
ATOM   3161 N  N   . THR B 2 76  ? 113.177 131.308 91.240  1.00 82.22  ? 76  THR B N   1 
ATOM   3162 C  CA  . THR B 2 76  ? 111.862 131.868 90.966  1.00 82.22  ? 76  THR B CA  1 
ATOM   3163 C  C   . THR B 2 76  ? 111.458 132.804 92.096  1.00 82.22  ? 76  THR B C   1 
ATOM   3164 O  O   . THR B 2 76  ? 111.538 132.438 93.276  1.00 82.22  ? 76  THR B O   1 
ATOM   3165 C  CB  . THR B 2 76  ? 110.817 130.762 90.798  1.00 82.22  ? 76  THR B CB  1 
ATOM   3166 O  OG1 . THR B 2 76  ? 111.253 129.839 89.792  1.00 82.22  ? 76  THR B OG1 1 
ATOM   3167 C  CG2 . THR B 2 76  ? 109.476 131.353 90.389  1.00 82.22  ? 76  THR B CG2 1 
ATOM   3168 N  N   . ILE B 2 77  ? 111.036 134.011 91.730  1.00 86.88  ? 77  ILE B N   1 
ATOM   3169 C  CA  . ILE B 2 77  ? 110.483 134.981 92.666  1.00 86.88  ? 77  ILE B CA  1 
ATOM   3170 C  C   . ILE B 2 77  ? 109.015 135.156 92.308  1.00 86.88  ? 77  ILE B C   1 
ATOM   3171 O  O   . ILE B 2 77  ? 108.684 135.665 91.229  1.00 86.88  ? 77  ILE B O   1 
ATOM   3172 C  CB  . ILE B 2 77  ? 111.232 136.318 92.619  1.00 86.88  ? 77  ILE B CB  1 
ATOM   3173 C  CG1 . ILE B 2 77  ? 112.696 136.124 93.017  1.00 86.88  ? 77  ILE B CG1 1 
ATOM   3174 C  CG2 . ILE B 2 77  ? 110.560 137.334 93.530  1.00 86.88  ? 77  ILE B CG2 1 
ATOM   3175 C  CD1 . ILE B 2 77  ? 113.570 137.329 92.745  1.00 86.88  ? 77  ILE B CD1 1 
ATOM   3176 N  N   . SER B 2 78  ? 108.133 134.729 93.208  1.00 93.69  ? 78  SER B N   1 
ATOM   3177 C  CA  . SER B 2 78  ? 106.693 134.813 92.992  1.00 93.69  ? 78  SER B CA  1 
ATOM   3178 C  C   . SER B 2 78  ? 106.175 136.080 93.661  1.00 93.69  ? 78  SER B C   1 
ATOM   3179 O  O   . SER B 2 78  ? 106.307 136.247 94.878  1.00 93.69  ? 78  SER B O   1 
ATOM   3180 C  CB  . SER B 2 78  ? 105.993 133.573 93.541  1.00 93.69  ? 78  SER B CB  1 
ATOM   3181 O  OG  . SER B 2 78  ? 104.607 133.806 93.719  1.00 93.69  ? 78  SER B OG  1 
ATOM   3182 N  N   . GLY B 2 79  ? 105.584 136.969 92.869  1.00 96.01  ? 79  GLY B N   1 
ATOM   3183 C  CA  . GLY B 2 79  ? 105.065 138.213 93.400  1.00 96.01  ? 79  GLY B CA  1 
ATOM   3184 C  C   . GLY B 2 79  ? 106.150 139.150 93.885  1.00 96.01  ? 79  GLY B C   1 
ATOM   3185 O  O   . GLY B 2 79  ? 106.293 139.366 95.092  1.00 96.01  ? 79  GLY B O   1 
ATOM   3186 N  N   . LEU B 2 80  ? 106.936 139.694 92.955  1.00 97.20  ? 80  LEU B N   1 
ATOM   3187 C  CA  . LEU B 2 80  ? 107.980 140.656 93.288  1.00 97.20  ? 80  LEU B CA  1 
ATOM   3188 C  C   . LEU B 2 80  ? 107.358 141.859 93.986  1.00 97.20  ? 80  LEU B C   1 
ATOM   3189 O  O   . LEU B 2 80  ? 106.654 142.650 93.350  1.00 97.20  ? 80  LEU B O   1 
ATOM   3190 C  CB  . LEU B 2 80  ? 108.713 141.082 92.015  1.00 97.20  ? 80  LEU B CB  1 
ATOM   3191 C  CG  . LEU B 2 80  ? 110.058 141.792 92.111  1.00 97.20  ? 80  LEU B CG  1 
ATOM   3192 C  CD1 . LEU B 2 80  ? 111.163 140.767 92.255  1.00 97.20  ? 80  LEU B CD1 1 
ATOM   3193 C  CD2 . LEU B 2 80  ? 110.275 142.637 90.874  1.00 97.20  ? 80  LEU B CD2 1 
ATOM   3194 N  N   . GLN B 2 81  ? 107.604 142.011 95.289  1.00 99.78  ? 81  GLN B N   1 
ATOM   3195 C  CA  . GLN B 2 81  ? 106.779 142.933 96.071  1.00 99.78  ? 81  GLN B CA  1 
ATOM   3196 C  C   . GLN B 2 81  ? 107.269 144.377 96.002  1.00 99.78  ? 81  GLN B C   1 
ATOM   3197 O  O   . GLN B 2 81  ? 106.630 145.230 95.379  1.00 99.78  ? 81  GLN B O   1 
ATOM   3198 C  CB  . GLN B 2 81  ? 106.722 142.459 97.528  1.00 99.78  ? 81  GLN B CB  1 
ATOM   3199 C  CG  . GLN B 2 81  ? 106.108 141.082 97.716  1.00 99.78  ? 81  GLN B CG  1 
ATOM   3200 C  CD  . GLN B 2 81  ? 106.276 140.554 99.127  1.00 99.78  ? 81  GLN B CD  1 
ATOM   3201 O  OE1 . GLN B 2 81  ? 106.889 141.201 99.976  1.00 99.78  ? 81  GLN B OE1 1 
ATOM   3202 N  NE2 . GLN B 2 81  ? 105.735 139.368 99.384  1.00 99.78  ? 81  GLN B NE2 1 
ATOM   3203 N  N   . ALA B 2 82  ? 108.406 144.672 96.634  1.00 96.47  ? 82  ALA B N   1 
ATOM   3204 C  CA  . ALA B 2 82  ? 108.796 146.072 96.769  1.00 96.47  ? 82  ALA B CA  1 
ATOM   3205 C  C   . ALA B 2 82  ? 110.184 146.414 96.241  1.00 96.47  ? 82  ALA B C   1 
ATOM   3206 O  O   . ALA B 2 82  ? 110.330 147.279 95.372  1.00 96.47  ? 82  ALA B O   1 
ATOM   3207 C  CB  . ALA B 2 82  ? 108.703 146.491 98.237  1.00 96.47  ? 82  ALA B CB  1 
ATOM   3208 N  N   . GLU B 2 83  ? 111.210 145.738 96.756  1.00 91.78  ? 83  GLU B N   1 
ATOM   3209 C  CA  . GLU B 2 83  ? 112.574 146.251 96.674  1.00 91.78  ? 83  GLU B CA  1 
ATOM   3210 C  C   . GLU B 2 83  ? 113.569 145.138 96.375  1.00 91.78  ? 83  GLU B C   1 
ATOM   3211 O  O   . GLU B 2 83  ? 114.766 145.258 96.653  1.00 91.78  ? 83  GLU B O   1 
ATOM   3212 C  CB  . GLU B 2 83  ? 112.932 147.010 97.956  1.00 91.78  ? 83  GLU B CB  1 
ATOM   3213 C  CG  . GLU B 2 83  ? 112.860 146.189 99.248  1.00 91.78  ? 83  GLU B CG  1 
ATOM   3214 C  CD  . GLU B 2 83  ? 114.148 145.469 99.606  1.00 91.78  ? 83  GLU B CD  1 
ATOM   3215 O  OE1 . GLU B 2 83  ? 115.225 145.874 99.122  1.00 91.78  ? 83  GLU B OE1 1 
ATOM   3216 O  OE2 . GLU B 2 83  ? 114.082 144.490 100.379 1.00 91.78  ? 83  GLU B OE2 1 
ATOM   3217 N  N   . ASP B 2 84  ? 113.106 144.062 95.747  1.00 92.39  ? 84  ASP B N   1 
ATOM   3218 C  CA  . ASP B 2 84  ? 113.999 142.977 95.358  1.00 92.39  ? 84  ASP B CA  1 
ATOM   3219 C  C   . ASP B 2 84  ? 114.952 143.366 94.230  1.00 92.39  ? 84  ASP B C   1 
ATOM   3220 O  O   . ASP B 2 84  ? 115.695 142.507 93.744  1.00 92.39  ? 84  ASP B O   1 
ATOM   3221 C  CB  . ASP B 2 84  ? 113.186 141.745 94.954  1.00 92.39  ? 84  ASP B CB  1 
ATOM   3222 C  CG  . ASP B 2 84  ? 112.460 141.116 96.126  1.00 92.39  ? 84  ASP B CG  1 
ATOM   3223 O  OD1 . ASP B 2 84  ? 112.957 141.232 97.266  1.00 92.39  ? 84  ASP B OD1 1 
ATOM   3224 O  OD2 . ASP B 2 84  ? 111.394 140.501 95.909  1.00 92.39  ? 84  ASP B OD2 1 
ATOM   3225 N  N   . GLU B 2 85  ? 114.942 144.628 93.805  1.00 92.34  ? 85  GLU B N   1 
ATOM   3226 C  CA  . GLU B 2 85  ? 115.870 145.100 92.787  1.00 92.34  ? 85  GLU B CA  1 
ATOM   3227 C  C   . GLU B 2 85  ? 117.296 145.051 93.320  1.00 92.34  ? 85  GLU B C   1 
ATOM   3228 O  O   . GLU B 2 85  ? 117.624 145.726 94.301  1.00 92.34  ? 85  GLU B O   1 
ATOM   3229 C  CB  . GLU B 2 85  ? 115.498 146.524 92.370  1.00 92.34  ? 85  GLU B CB  1 
ATOM   3230 C  CG  . GLU B 2 85  ? 116.652 147.349 91.818  1.00 92.34  ? 85  GLU B CG  1 
ATOM   3231 C  CD  . GLU B 2 85  ? 116.216 148.723 91.353  1.00 92.34  ? 85  GLU B CD  1 
ATOM   3232 O  OE1 . GLU B 2 85  ? 115.108 148.837 90.786  1.00 92.34  ? 85  GLU B OE1 1 
ATOM   3233 O  OE2 . GLU B 2 85  ? 116.981 149.690 91.552  1.00 92.34  ? 85  GLU B OE2 1 
ATOM   3234 N  N   . ALA B 2 86  ? 118.142 144.252 92.675  1.00 83.61  ? 86  ALA B N   1 
ATOM   3235 C  CA  . ALA B 2 86  ? 119.511 144.034 93.134  1.00 83.61  ? 86  ALA B CA  1 
ATOM   3236 C  C   . ALA B 2 86  ? 120.263 143.258 92.059  1.00 83.61  ? 86  ALA B C   1 
ATOM   3237 O  O   . ALA B 2 86  ? 119.736 142.982 90.975  1.00 83.61  ? 86  ALA B O   1 
ATOM   3238 C  CB  . ALA B 2 86  ? 119.540 143.292 94.473  1.00 83.61  ? 86  ALA B CB  1 
ATOM   3239 N  N   . ASP B 2 87  ? 121.505 142.895 92.372  1.00 78.57  ? 87  ASP B N   1 
ATOM   3240 C  CA  . ASP B 2 87  ? 122.312 142.041 91.511  1.00 78.57  ? 87  ASP B CA  1 
ATOM   3241 C  C   . ASP B 2 87  ? 122.267 140.621 92.060  1.00 78.57  ? 87  ASP B C   1 
ATOM   3242 O  O   . ASP B 2 87  ? 122.672 140.380 93.201  1.00 78.57  ? 87  ASP B O   1 
ATOM   3243 C  CB  . ASP B 2 87  ? 123.751 142.548 91.436  1.00 78.57  ? 87  ASP B CB  1 
ATOM   3244 C  CG  . ASP B 2 87  ? 123.855 143.908 90.782  1.00 78.57  ? 87  ASP B CG  1 
ATOM   3245 O  OD1 . ASP B 2 87  ? 123.424 144.043 89.618  1.00 78.57  ? 87  ASP B OD1 1 
ATOM   3246 O  OD2 . ASP B 2 87  ? 124.368 144.844 91.431  1.00 78.57  ? 87  ASP B OD2 1 
ATOM   3247 N  N   . TYR B 2 88  ? 121.775 139.689 91.251  1.00 77.51  ? 88  TYR B N   1 
ATOM   3248 C  CA  . TYR B 2 88  ? 121.620 138.298 91.652  1.00 77.51  ? 88  TYR B CA  1 
ATOM   3249 C  C   . TYR B 2 88  ? 122.679 137.452 90.960  1.00 77.51  ? 88  TYR B C   1 
ATOM   3250 O  O   . TYR B 2 88  ? 122.933 137.621 89.761  1.00 77.51  ? 88  TYR B O   1 
ATOM   3251 C  CB  . TYR B 2 88  ? 120.219 137.790 91.313  1.00 77.51  ? 88  TYR B CB  1 
ATOM   3252 C  CG  . TYR B 2 88  ? 119.158 138.232 92.295  1.00 77.51  ? 88  TYR B CG  1 
ATOM   3253 C  CD1 . TYR B 2 88  ? 118.785 139.565 92.389  1.00 77.51  ? 88  TYR B CD1 1 
ATOM   3254 C  CD2 . TYR B 2 88  ? 118.530 137.316 93.129  1.00 77.51  ? 88  TYR B CD2 1 
ATOM   3255 C  CE1 . TYR B 2 88  ? 117.816 139.975 93.284  1.00 77.51  ? 88  TYR B CE1 1 
ATOM   3256 C  CE2 . TYR B 2 88  ? 117.560 137.716 94.027  1.00 77.51  ? 88  TYR B CE2 1 
ATOM   3257 C  CZ  . TYR B 2 88  ? 117.207 139.047 94.101  1.00 77.51  ? 88  TYR B CZ  1 
ATOM   3258 O  OH  . TYR B 2 88  ? 116.241 139.452 94.994  1.00 77.51  ? 88  TYR B OH  1 
ATOM   3259 N  N   . TYR B 2 89  ? 123.293 136.549 91.717  1.00 72.00  ? 89  TYR B N   1 
ATOM   3260 C  CA  . TYR B 2 89  ? 124.406 135.744 91.241  1.00 72.00  ? 89  TYR B CA  1 
ATOM   3261 C  C   . TYR B 2 89  ? 124.162 134.273 91.554  1.00 72.00  ? 89  TYR B C   1 
ATOM   3262 O  O   . TYR B 2 89  ? 123.605 133.934 92.605  1.00 72.00  ? 89  TYR B O   1 
ATOM   3263 C  CB  . TYR B 2 89  ? 125.724 136.195 91.884  1.00 72.00  ? 89  TYR B CB  1 
ATOM   3264 C  CG  . TYR B 2 89  ? 126.173 137.583 91.486  1.00 72.00  ? 89  TYR B CG  1 
ATOM   3265 C  CD1 . TYR B 2 89  ? 125.691 138.702 92.148  1.00 72.00  ? 89  TYR B CD1 1 
ATOM   3266 C  CD2 . TYR B 2 89  ? 127.078 137.772 90.451  1.00 72.00  ? 89  TYR B CD2 1 
ATOM   3267 C  CE1 . TYR B 2 89  ? 126.093 139.967 91.791  1.00 72.00  ? 89  TYR B CE1 1 
ATOM   3268 C  CE2 . TYR B 2 89  ? 127.493 139.035 90.090  1.00 72.00  ? 89  TYR B CE2 1 
ATOM   3269 C  CZ  . TYR B 2 89  ? 126.992 140.133 90.759  1.00 72.00  ? 89  TYR B CZ  1 
ATOM   3270 O  OH  . TYR B 2 89  ? 127.396 141.402 90.403  1.00 72.00  ? 89  TYR B OH  1 
ATOM   3271 N  N   . CYS B 2 90  ? 124.589 133.408 90.639  1.00 72.57  ? 90  CYS B N   1 
ATOM   3272 C  CA  . CYS B 2 90  ? 124.542 131.963 90.812  1.00 72.57  ? 90  CYS B CA  1 
ATOM   3273 C  C   . CYS B 2 90  ? 125.955 131.448 91.038  1.00 72.57  ? 90  CYS B C   1 
ATOM   3274 O  O   . CYS B 2 90  ? 126.894 131.885 90.363  1.00 72.57  ? 90  CYS B O   1 
ATOM   3275 C  CB  . CYS B 2 90  ? 123.920 131.281 89.592  1.00 72.57  ? 90  CYS B CB  1 
ATOM   3276 S  SG  . CYS B 2 90  ? 124.774 131.611 88.032  1.00 72.57  ? 90  CYS B SG  1 
ATOM   3277 N  N   . SER B 2 91  ? 126.106 130.523 91.980  1.00 65.80  ? 91  SER B N   1 
ATOM   3278 C  CA  . SER B 2 91  ? 127.400 129.953 92.319  1.00 65.80  ? 91  SER B CA  1 
ATOM   3279 C  C   . SER B 2 91  ? 127.293 128.437 92.349  1.00 65.80  ? 91  SER B C   1 
ATOM   3280 O  O   . SER B 2 91  ? 126.259 127.888 92.738  1.00 65.80  ? 91  SER B O   1 
ATOM   3281 C  CB  . SER B 2 91  ? 127.888 130.459 93.672  1.00 65.80  ? 91  SER B CB  1 
ATOM   3282 O  OG  . SER B 2 91  ? 126.930 130.181 94.675  1.00 65.80  ? 91  SER B OG  1 
ATOM   3283 N  N   . SER B 2 92  ? 128.368 127.768 91.948  1.00 64.37  ? 92  SER B N   1 
ATOM   3284 C  CA  . SER B 2 92  ? 128.414 126.314 91.926  1.00 64.37  ? 92  SER B CA  1 
ATOM   3285 C  C   . SER B 2 92  ? 129.740 125.830 92.491  1.00 64.37  ? 92  SER B C   1 
ATOM   3286 O  O   . SER B 2 92  ? 130.734 126.562 92.506  1.00 64.37  ? 92  SER B O   1 
ATOM   3287 C  CB  . SER B 2 92  ? 128.224 125.762 90.510  1.00 64.37  ? 92  SER B CB  1 
ATOM   3288 O  OG  . SER B 2 92  ? 128.229 124.346 90.518  1.00 64.37  ? 92  SER B OG  1 
ATOM   3289 N  N   . TYR B 2 93  ? 129.744 124.586 92.963  1.00 60.88  ? 93  TYR B N   1 
ATOM   3290 C  CA  . TYR B 2 93  ? 130.936 123.953 93.516  1.00 60.88  ? 93  TYR B CA  1 
ATOM   3291 C  C   . TYR B 2 93  ? 131.453 122.945 92.498  1.00 60.88  ? 93  TYR B C   1 
ATOM   3292 O  O   . TYR B 2 93  ? 130.692 122.105 92.006  1.00 60.88  ? 93  TYR B O   1 
ATOM   3293 C  CB  . TYR B 2 93  ? 130.638 123.284 94.854  1.00 60.88  ? 93  TYR B CB  1 
ATOM   3294 C  CG  . TYR B 2 93  ? 131.881 123.003 95.659  1.00 60.88  ? 93  TYR B CG  1 
ATOM   3295 C  CD1 . TYR B 2 93  ? 132.971 123.858 95.600  1.00 60.88  ? 93  TYR B CD1 1 
ATOM   3296 C  CD2 . TYR B 2 93  ? 131.968 121.886 96.472  1.00 60.88  ? 93  TYR B CD2 1 
ATOM   3297 C  CE1 . TYR B 2 93  ? 134.113 123.610 96.328  1.00 60.88  ? 93  TYR B CE1 1 
ATOM   3298 C  CE2 . TYR B 2 93  ? 133.105 121.629 97.204  1.00 60.88  ? 93  TYR B CE2 1 
ATOM   3299 C  CZ  . TYR B 2 93  ? 134.175 122.494 97.129  1.00 60.88  ? 93  TYR B CZ  1 
ATOM   3300 O  OH  . TYR B 2 93  ? 135.314 122.244 97.860  1.00 60.88  ? 93  TYR B OH  1 
ATOM   3301 N  N   . THR B 2 94  ? 132.744 123.025 92.189  1.00 60.67  ? 94  THR B N   1 
ATOM   3302 C  CA  . THR B 2 94  ? 133.321 122.204 91.140  1.00 60.67  ? 94  THR B CA  1 
ATOM   3303 C  C   . THR B 2 94  ? 134.015 120.976 91.726  1.00 60.67  ? 94  THR B C   1 
ATOM   3304 O  O   . THR B 2 94  ? 134.206 120.847 92.938  1.00 60.67  ? 94  THR B O   1 
ATOM   3305 C  CB  . THR B 2 94  ? 134.309 123.016 90.307  1.00 60.67  ? 94  THR B CB  1 
ATOM   3306 O  OG1 . THR B 2 94  ? 135.505 123.240 91.064  1.00 60.67  ? 94  THR B OG1 1 
ATOM   3307 C  CG2 . THR B 2 94  ? 133.701 124.351 89.926  1.00 60.67  ? 94  THR B CG2 1 
ATOM   3308 N  N   . SER B 2 95  ? 134.394 120.061 90.832  1.00 59.27  ? 95  SER B N   1 
ATOM   3309 C  CA  . SER B 2 95  ? 135.094 118.849 91.238  1.00 59.27  ? 95  SER B CA  1 
ATOM   3310 C  C   . SER B 2 95  ? 136.491 119.135 91.770  1.00 59.27  ? 95  SER B C   1 
ATOM   3311 O  O   . SER B 2 95  ? 137.045 118.302 92.496  1.00 59.27  ? 95  SER B O   1 
ATOM   3312 C  CB  . SER B 2 95  ? 135.179 117.875 90.063  1.00 59.27  ? 95  SER B CB  1 
ATOM   3313 O  OG  . SER B 2 95  ? 133.955 117.187 89.879  1.00 59.27  ? 95  SER B OG  1 
ATOM   3314 N  N   . SER B 2 96  ? 137.071 120.284 91.429  1.00 59.30  ? 96  SER B N   1 
ATOM   3315 C  CA  . SER B 2 96  ? 138.421 120.633 91.850  1.00 59.30  ? 96  SER B CA  1 
ATOM   3316 C  C   . SER B 2 96  ? 138.454 121.422 93.153  1.00 59.30  ? 96  SER B C   1 
ATOM   3317 O  O   . SER B 2 96  ? 139.430 122.143 93.396  1.00 59.30  ? 96  SER B O   1 
ATOM   3318 C  CB  . SER B 2 96  ? 139.129 121.421 90.746  1.00 59.30  ? 96  SER B CB  1 
ATOM   3319 O  OG  . SER B 2 96  ? 140.472 121.698 91.100  1.00 59.30  ? 96  SER B OG  1 
ATOM   3320 N  N   . SER B 2 97  ? 137.418 121.298 93.986  1.00 61.37  ? 97  SER B N   1 
ATOM   3321 C  CA  . SER B 2 97  ? 137.335 122.003 95.266  1.00 61.37  ? 97  SER B CA  1 
ATOM   3322 C  C   . SER B 2 97  ? 137.436 123.516 95.078  1.00 61.37  ? 97  SER B C   1 
ATOM   3323 O  O   . SER B 2 97  ? 138.103 124.213 95.845  1.00 61.37  ? 97  SER B O   1 
ATOM   3324 C  CB  . SER B 2 97  ? 138.400 121.504 96.246  1.00 61.37  ? 97  SER B CB  1 
ATOM   3325 O  OG  . SER B 2 97  ? 138.195 120.140 96.571  1.00 61.37  ? 97  SER B OG  1 
ATOM   3326 N  N   . THR B 2 98  ? 136.767 124.027 94.047  1.00 62.08  ? 98  THR B N   1 
ATOM   3327 C  CA  . THR B 2 98  ? 136.751 125.450 93.747  1.00 62.08  ? 98  THR B CA  1 
ATOM   3328 C  C   . THR B 2 98  ? 135.319 125.904 93.514  1.00 62.08  ? 98  THR B C   1 
ATOM   3329 O  O   . THR B 2 98  ? 134.466 125.127 93.077  1.00 62.08  ? 98  THR B O   1 
ATOM   3330 C  CB  . THR B 2 98  ? 137.603 125.786 92.513  1.00 62.08  ? 98  THR B CB  1 
ATOM   3331 O  OG1 . THR B 2 98  ? 137.166 124.999 91.399  1.00 62.08  ? 98  THR B OG1 1 
ATOM   3332 C  CG2 . THR B 2 98  ? 139.073 125.504 92.781  1.00 62.08  ? 98  THR B CG2 1 
ATOM   3333 N  N   . TRP B 2 99  ? 135.064 127.173 93.814  1.00 62.94  ? 99  TRP B N   1 
ATOM   3334 C  CA  . TRP B 2 99  ? 133.749 127.775 93.650  1.00 62.94  ? 99  TRP B CA  1 
ATOM   3335 C  C   . TRP B 2 99  ? 133.747 128.618 92.382  1.00 62.94  ? 99  TRP B C   1 
ATOM   3336 O  O   . TRP B 2 99  ? 134.707 129.349 92.119  1.00 62.94  ? 99  TRP B O   1 
ATOM   3337 C  CB  . TRP B 2 99  ? 133.398 128.644 94.858  1.00 62.94  ? 99  TRP B CB  1 
ATOM   3338 C  CG  . TRP B 2 99  ? 132.637 127.938 95.934  1.00 62.94  ? 99  TRP B CG  1 
ATOM   3339 C  CD1 . TRP B 2 99  ? 133.157 127.364 97.056  1.00 62.94  ? 99  TRP B CD1 1 
ATOM   3340 C  CD2 . TRP B 2 99  ? 131.220 127.742 96.004  1.00 62.94  ? 99  TRP B CD2 1 
ATOM   3341 N  NE1 . TRP B 2 99  ? 132.155 126.818 97.817  1.00 62.94  ? 99  TRP B NE1 1 
ATOM   3342 C  CE2 . TRP B 2 99  ? 130.956 127.036 97.193  1.00 62.94  ? 99  TRP B CE2 1 
ATOM   3343 C  CE3 . TRP B 2 99  ? 130.150 128.092 95.176  1.00 62.94  ? 99  TRP B CE3 1 
ATOM   3344 C  CZ2 . TRP B 2 99  ? 129.668 126.673 97.575  1.00 62.94  ? 99  TRP B CZ2 1 
ATOM   3345 C  CZ3 . TRP B 2 99  ? 128.872 127.728 95.557  1.00 62.94  ? 99  TRP B CZ3 1 
ATOM   3346 C  CH2 . TRP B 2 99  ? 128.642 127.027 96.746  1.00 62.94  ? 99  TRP B CH2 1 
ATOM   3347 N  N   . VAL B 2 100 ? 132.678 128.514 91.599  1.00 65.38  ? 100 VAL B N   1 
ATOM   3348 C  CA  . VAL B 2 100 ? 132.526 129.288 90.373  1.00 65.38  ? 100 VAL B CA  1 
ATOM   3349 C  C   . VAL B 2 100 ? 131.314 130.196 90.512  1.00 65.38  ? 100 VAL B C   1 
ATOM   3350 O  O   . VAL B 2 100 ? 130.251 129.768 90.978  1.00 65.38  ? 100 VAL B O   1 
ATOM   3351 C  CB  . VAL B 2 100 ? 132.400 128.384 89.128  1.00 65.38  ? 100 VAL B CB  1 
ATOM   3352 C  CG1 . VAL B 2 100 ? 133.743 127.757 88.799  1.00 65.38  ? 100 VAL B CG1 1 
ATOM   3353 C  CG2 . VAL B 2 100 ? 131.353 127.306 89.350  1.00 65.38  ? 100 VAL B CG2 1 
ATOM   3354 N  N   . PHE B 2 101 ? 131.484 131.454 90.114  1.00 65.07  ? 101 PHE B N   1 
ATOM   3355 C  CA  . PHE B 2 101 ? 130.455 132.478 90.223  1.00 65.07  ? 101 PHE B CA  1 
ATOM   3356 C  C   . PHE B 2 101 ? 129.905 132.814 88.844  1.00 65.07  ? 101 PHE B C   1 
ATOM   3357 O  O   . PHE B 2 101 ? 130.650 132.848 87.859  1.00 65.07  ? 101 PHE B O   1 
ATOM   3358 C  CB  . PHE B 2 101 ? 131.009 133.746 90.877  1.00 65.07  ? 101 PHE B CB  1 
ATOM   3359 C  CG  . PHE B 2 101 ? 130.987 133.715 92.376  1.00 65.07  ? 101 PHE B CG  1 
ATOM   3360 C  CD1 . PHE B 2 101 ? 129.788 133.738 93.065  1.00 65.07  ? 101 PHE B CD1 1 
ATOM   3361 C  CD2 . PHE B 2 101 ? 132.168 133.673 93.098  1.00 65.07  ? 101 PHE B CD2 1 
ATOM   3362 C  CE1 . PHE B 2 101 ? 129.765 133.712 94.444  1.00 65.07  ? 101 PHE B CE1 1 
ATOM   3363 C  CE2 . PHE B 2 101 ? 132.151 133.648 94.477  1.00 65.07  ? 101 PHE B CE2 1 
ATOM   3364 C  CZ  . PHE B 2 101 ? 130.948 133.667 95.151  1.00 65.07  ? 101 PHE B CZ  1 
ATOM   3365 N  N   . GLY B 2 102 ? 128.598 133.062 88.780  1.00 72.01  ? 102 GLY B N   1 
ATOM   3366 C  CA  . GLY B 2 102 ? 127.974 133.444 87.533  1.00 72.01  ? 102 GLY B CA  1 
ATOM   3367 C  C   . GLY B 2 102 ? 128.285 134.877 87.141  1.00 72.01  ? 102 GLY B C   1 
ATOM   3368 O  O   . GLY B 2 102 ? 128.866 135.652 87.899  1.00 72.01  ? 102 GLY B O   1 
ATOM   3369 N  N   . GLY B 2 103 ? 127.886 135.224 85.915  1.00 74.45  ? 103 GLY B N   1 
ATOM   3370 C  CA  . GLY B 2 103 ? 128.131 136.567 85.418  1.00 74.45  ? 103 GLY B CA  1 
ATOM   3371 C  C   . GLY B 2 103 ? 127.393 137.640 86.191  1.00 74.45  ? 103 GLY B C   1 
ATOM   3372 O  O   . GLY B 2 103 ? 127.948 138.711 86.453  1.00 74.45  ? 103 GLY B O   1 
ATOM   3373 N  N   . GLY B 2 104 ? 126.154 137.377 86.565  1.00 77.09  ? 104 GLY B N   1 
ATOM   3374 C  CA  . GLY B 2 104 ? 125.360 138.325 87.316  1.00 77.09  ? 104 GLY B CA  1 
ATOM   3375 C  C   . GLY B 2 104 ? 124.166 138.816 86.517  1.00 77.09  ? 104 GLY B C   1 
ATOM   3376 O  O   . GLY B 2 104 ? 124.223 138.976 85.290  1.00 77.09  ? 104 GLY B O   1 
ATOM   3377 N  N   . THR B 2 105 ? 123.064 139.059 87.223  1.00 80.37  ? 105 THR B N   1 
ATOM   3378 C  CA  . THR B 2 105 ? 121.833 139.542 86.612  1.00 80.37  ? 105 THR B CA  1 
ATOM   3379 C  C   . THR B 2 105 ? 121.325 140.743 87.395  1.00 80.37  ? 105 THR B C   1 
ATOM   3380 O  O   . THR B 2 105 ? 121.185 140.674 88.618  1.00 80.37  ? 105 THR B O   1 
ATOM   3381 C  CB  . THR B 2 105 ? 120.762 138.445 86.576  1.00 80.37  ? 105 THR B CB  1 
ATOM   3382 O  OG1 . THR B 2 105 ? 121.200 137.373 85.732  1.00 80.37  ? 105 THR B OG1 1 
ATOM   3383 C  CG2 . THR B 2 105 ? 119.448 138.996 86.044  1.00 80.37  ? 105 THR B CG2 1 
ATOM   3384 N  N   . LYS B 2 106 ? 121.041 141.835 86.692  1.00 83.72  ? 106 LYS B N   1 
ATOM   3385 C  CA  . LYS B 2 106 ? 120.529 143.052 87.309  1.00 83.72  ? 106 LYS B CA  1 
ATOM   3386 C  C   . LYS B 2 106 ? 119.007 143.044 87.242  1.00 83.72  ? 106 LYS B C   1 
ATOM   3387 O  O   . LYS B 2 106 ? 118.431 143.164 86.155  1.00 83.72  ? 106 LYS B O   1 
ATOM   3388 C  CB  . LYS B 2 106 ? 121.089 144.293 86.615  1.00 83.72  ? 106 LYS B CB  1 
ATOM   3389 C  CG  . LYS B 2 106 ? 121.394 145.447 87.555  1.00 83.72  ? 106 LYS B CG  1 
ATOM   3390 C  CD  . LYS B 2 106 ? 122.417 146.396 86.953  1.00 83.72  ? 106 LYS B CD  1 
ATOM   3391 C  CE  . LYS B 2 106 ? 123.214 147.106 88.034  1.00 83.72  ? 106 LYS B CE  1 
ATOM   3392 N  NZ  . LYS B 2 106 ? 124.371 147.855 87.471  1.00 83.72  ? 106 LYS B NZ  1 
ATOM   3393 N  N   . LEU B 2 107 ? 118.360 142.903 88.398  1.00 88.96  ? 107 LEU B N   1 
ATOM   3394 C  CA  . LEU B 2 107 ? 116.907 142.953 88.495  1.00 88.96  ? 107 LEU B CA  1 
ATOM   3395 C  C   . LEU B 2 107 ? 116.529 144.349 88.974  1.00 88.96  ? 107 LEU B C   1 
ATOM   3396 O  O   . LEU B 2 107 ? 116.848 144.730 90.105  1.00 88.96  ? 107 LEU B O   1 
ATOM   3397 C  CB  . LEU B 2 107 ? 116.388 141.877 89.446  1.00 88.96  ? 107 LEU B CB  1 
ATOM   3398 C  CG  . LEU B 2 107 ? 114.895 141.893 89.775  1.00 88.96  ? 107 LEU B CG  1 
ATOM   3399 C  CD1 . LEU B 2 107 ? 114.067 141.544 88.550  1.00 88.96  ? 107 LEU B CD1 1 
ATOM   3400 C  CD2 . LEU B 2 107 ? 114.595 140.938 90.918  1.00 88.96  ? 107 LEU B CD2 1 
ATOM   3401 N  N   . THR B 2 108 ? 115.855 145.106 88.112  1.00 96.63  ? 108 THR B N   1 
ATOM   3402 C  CA  . THR B 2 108 ? 115.539 146.505 88.359  1.00 96.63  ? 108 THR B CA  1 
ATOM   3403 C  C   . THR B 2 108 ? 114.030 146.685 88.451  1.00 96.63  ? 108 THR B C   1 
ATOM   3404 O  O   . THR B 2 108 ? 113.276 146.097 87.670  1.00 96.63  ? 108 THR B O   1 
ATOM   3405 C  CB  . THR B 2 108 ? 116.109 147.402 87.251  1.00 96.63  ? 108 THR B CB  1 
ATOM   3406 O  OG1 . THR B 2 108 ? 117.501 147.114 87.071  1.00 96.63  ? 108 THR B OG1 1 
ATOM   3407 C  CG2 . THR B 2 108 ? 115.946 148.872 87.607  1.00 96.63  ? 108 THR B CG2 1 
ATOM   3408 N  N   . VAL B 2 109 ? 113.597 147.502 89.409  1.00 107.71 ? 109 VAL B N   1 
ATOM   3409 C  CA  . VAL B 2 109 ? 112.183 147.757 89.647  1.00 107.71 ? 109 VAL B CA  1 
ATOM   3410 C  C   . VAL B 2 109 ? 111.922 149.249 89.509  1.00 107.71 ? 109 VAL B C   1 
ATOM   3411 O  O   . VAL B 2 109 ? 112.589 150.077 90.137  1.00 107.71 ? 109 VAL B O   1 
ATOM   3412 C  CB  . VAL B 2 109 ? 111.740 147.258 91.040  1.00 107.71 ? 109 VAL B CB  1 
ATOM   3413 C  CG1 . VAL B 2 109 ? 110.287 147.624 91.305  1.00 107.71 ? 109 VAL B CG1 1 
ATOM   3414 C  CG2 . VAL B 2 109 ? 111.960 145.762 91.165  1.00 107.71 ? 109 VAL B CG2 1 
ATOM   3415 N  N   . LEU B 2 110 ? 110.940 149.591 88.680  1.00 121.27 ? 110 LEU B N   1 
ATOM   3416 C  CA  . LEU B 2 110 ? 110.533 150.979 88.512  1.00 121.27 ? 110 LEU B CA  1 
ATOM   3417 C  C   . LEU B 2 110 ? 109.725 151.417 89.733  1.00 121.27 ? 110 LEU B C   1 
ATOM   3418 O  O   . LEU B 2 110 ? 109.193 150.596 90.485  1.00 121.27 ? 110 LEU B O   1 
ATOM   3419 C  CB  . LEU B 2 110 ? 109.752 151.153 87.211  1.00 121.27 ? 110 LEU B CB  1 
ATOM   3420 C  CG  . LEU B 2 110 ? 110.540 151.098 85.898  1.00 121.27 ? 110 LEU B CG  1 
ATOM   3421 C  CD1 . LEU B 2 110 ? 110.737 149.663 85.425  1.00 121.27 ? 110 LEU B CD1 1 
ATOM   3422 C  CD2 . LEU B 2 110 ? 109.853 151.929 84.824  1.00 121.27 ? 110 LEU B CD2 1 
ATOM   3423 N  N   . GLY B 2 111 ? 109.621 152.726 89.943  1.00 133.02 ? 111 GLY B N   1 
ATOM   3424 C  CA  . GLY B 2 111 ? 108.892 153.245 91.083  1.00 133.02 ? 111 GLY B CA  1 
ATOM   3425 C  C   . GLY B 2 111 ? 107.664 154.039 90.693  1.00 133.02 ? 111 GLY B C   1 
ATOM   3426 O  O   . GLY B 2 111 ? 106.769 154.257 91.515  1.00 133.02 ? 111 GLY B O   1 
ATOM   3427 N  N   . GLN B 2 112 ? 107.610 154.475 89.439  1.00 142.07 ? 112 GLN B N   1 
ATOM   3428 C  CA  . GLN B 2 112 ? 106.478 155.239 88.934  1.00 142.07 ? 112 GLN B CA  1 
ATOM   3429 C  C   . GLN B 2 112 ? 106.467 155.122 87.418  1.00 142.07 ? 112 GLN B C   1 
ATOM   3430 O  O   . GLN B 2 112 ? 107.529 155.026 86.785  1.00 142.07 ? 112 GLN B O   1 
ATOM   3431 C  CB  . GLN B 2 112 ? 106.551 156.712 89.378  1.00 142.07 ? 112 GLN B CB  1 
ATOM   3432 C  CG  . GLN B 2 112 ? 107.743 157.485 88.830  1.00 142.07 ? 112 GLN B CG  1 
ATOM   3433 C  CD  . GLN B 2 112 ? 107.434 158.191 87.525  1.00 142.07 ? 112 GLN B CD  1 
ATOM   3434 O  OE1 . GLN B 2 112 ? 106.299 158.600 87.280  1.00 142.07 ? 112 GLN B OE1 1 
ATOM   3435 N  NE2 . GLN B 2 112 ? 108.446 158.338 86.677  1.00 142.07 ? 112 GLN B NE2 1 
ATOM   3436 N  N   . PRO B 2 113 ? 105.277 155.115 86.798  1.00 145.05 ? 113 PRO B N   1 
ATOM   3437 C  CA  . PRO B 2 113 ? 105.148 155.047 85.338  1.00 145.05 ? 113 PRO B CA  1 
ATOM   3438 C  C   . PRO B 2 113 ? 105.718 156.280 84.643  1.00 145.05 ? 113 PRO B C   1 
ATOM   3439 O  O   . PRO B 2 113 ? 106.897 156.276 84.289  1.00 145.05 ? 113 PRO B O   1 
ATOM   3440 C  CB  . PRO B 2 113 ? 103.633 154.953 85.119  1.00 145.05 ? 113 PRO B CB  1 
ATOM   3441 C  CG  . PRO B 2 113 ? 103.077 154.484 86.423  1.00 145.05 ? 113 PRO B CG  1 
ATOM   3442 C  CD  . PRO B 2 113 ? 103.967 155.072 87.469  1.00 145.05 ? 113 PRO B CD  1 
ATOM   3443 N  N   . GLN C 3 1   ? 128.988 140.659 116.958 1.00 78.01  ? 1   GLN C N   1 
ATOM   3444 C  CA  . GLN C 3 1   ? 127.870 140.603 116.024 1.00 78.01  ? 1   GLN C CA  1 
ATOM   3445 C  C   . GLN C 3 1   ? 128.341 140.855 114.595 1.00 78.01  ? 1   GLN C C   1 
ATOM   3446 O  O   . GLN C 3 1   ? 127.710 140.412 113.635 1.00 78.01  ? 1   GLN C O   1 
ATOM   3447 C  CB  . GLN C 3 1   ? 126.791 141.616 116.414 1.00 78.01  ? 1   GLN C CB  1 
ATOM   3448 C  CG  . GLN C 3 1   ? 127.254 143.066 116.394 1.00 78.01  ? 1   GLN C CG  1 
ATOM   3449 C  CD  . GLN C 3 1   ? 127.843 143.512 117.719 1.00 78.01  ? 1   GLN C CD  1 
ATOM   3450 O  OE1 . GLN C 3 1   ? 128.144 142.691 118.586 1.00 78.01  ? 1   GLN C OE1 1 
ATOM   3451 N  NE2 . GLN C 3 1   ? 128.012 144.819 117.881 1.00 78.01  ? 1   GLN C NE2 1 
ATOM   3452 N  N   . VAL C 3 2   ? 129.458 141.573 114.461 1.00 74.35  ? 2   VAL C N   1 
ATOM   3453 C  CA  . VAL C 3 2   ? 130.005 141.863 113.141 1.00 74.35  ? 2   VAL C CA  1 
ATOM   3454 C  C   . VAL C 3 2   ? 130.652 140.640 112.504 1.00 74.35  ? 2   VAL C C   1 
ATOM   3455 O  O   . VAL C 3 2   ? 130.935 140.659 111.299 1.00 74.35  ? 2   VAL C O   1 
ATOM   3456 C  CB  . VAL C 3 2   ? 131.024 143.011 113.217 1.00 74.35  ? 2   VAL C CB  1 
ATOM   3457 C  CG1 . VAL C 3 2   ? 130.318 144.327 113.503 1.00 74.35  ? 2   VAL C CG1 1 
ATOM   3458 C  CG2 . VAL C 3 2   ? 132.067 142.719 114.285 1.00 74.35  ? 2   VAL C CG2 1 
ATOM   3459 N  N   . GLN C 3 3   ? 130.912 139.591 113.288 1.00 70.94  ? 3   GLN C N   1 
ATOM   3460 C  CA  . GLN C 3 3   ? 131.488 138.340 112.803 1.00 70.94  ? 3   GLN C CA  1 
ATOM   3461 C  C   . GLN C 3 3   ? 132.892 138.546 112.246 1.00 70.94  ? 3   GLN C C   1 
ATOM   3462 O  O   . GLN C 3 3   ? 133.874 138.118 112.859 1.00 70.94  ? 3   GLN C O   1 
ATOM   3463 C  CB  . GLN C 3 3   ? 130.583 137.695 111.750 1.00 70.94  ? 3   GLN C CB  1 
ATOM   3464 C  CG  . GLN C 3 3   ? 129.224 137.271 112.281 1.00 70.94  ? 3   GLN C CG  1 
ATOM   3465 C  CD  . GLN C 3 3   ? 129.269 136.864 113.741 1.00 70.94  ? 3   GLN C CD  1 
ATOM   3466 O  OE1 . GLN C 3 3   ? 128.800 137.592 114.615 1.00 70.94  ? 3   GLN C OE1 1 
ATOM   3467 N  NE2 . GLN C 3 3   ? 129.832 135.692 114.011 1.00 70.94  ? 3   GLN C NE2 1 
ATOM   3468 N  N   . LEU C 3 4   ? 133.002 139.199 111.091 1.00 66.31  ? 4   LEU C N   1 
ATOM   3469 C  CA  . LEU C 3 4   ? 134.286 139.403 110.434 1.00 66.31  ? 4   LEU C CA  1 
ATOM   3470 C  C   . LEU C 3 4   ? 134.488 140.882 110.142 1.00 66.31  ? 4   LEU C C   1 
ATOM   3471 O  O   . LEU C 3 4   ? 133.603 141.534 109.578 1.00 66.31  ? 4   LEU C O   1 
ATOM   3472 C  CB  . LEU C 3 4   ? 134.377 138.593 109.135 1.00 66.31  ? 4   LEU C CB  1 
ATOM   3473 C  CG  . LEU C 3 4   ? 133.958 137.123 109.202 1.00 66.31  ? 4   LEU C CG  1 
ATOM   3474 C  CD1 . LEU C 3 4   ? 133.768 136.555 107.804 1.00 66.31  ? 4   LEU C CD1 1 
ATOM   3475 C  CD2 . LEU C 3 4   ? 134.979 136.306 109.978 1.00 66.31  ? 4   LEU C CD2 1 
ATOM   3476 N  N   . VAL C 3 5   ? 135.649 141.403 110.527 1.00 66.77  ? 5   VAL C N   1 
ATOM   3477 C  CA  . VAL C 3 5   ? 136.072 142.760 110.200 1.00 66.77  ? 5   VAL C CA  1 
ATOM   3478 C  C   . VAL C 3 5   ? 137.413 142.651 109.491 1.00 66.77  ? 5   VAL C C   1 
ATOM   3479 O  O   . VAL C 3 5   ? 138.333 141.996 109.996 1.00 66.77  ? 5   VAL C O   1 
ATOM   3480 C  CB  . VAL C 3 5   ? 136.180 143.647 111.451 1.00 66.77  ? 5   VAL C CB  1 
ATOM   3481 C  CG1 . VAL C 3 5   ? 136.747 145.011 111.089 1.00 66.77  ? 5   VAL C CG1 1 
ATOM   3482 C  CG2 . VAL C 3 5   ? 134.821 143.790 112.116 1.00 66.77  ? 5   VAL C CG2 1 
ATOM   3483 N  N   . GLN C 3 6   ? 137.531 143.288 108.325 1.00 65.88  ? 6   GLN C N   1 
ATOM   3484 C  CA  . GLN C 3 6   ? 138.704 143.062 107.472 1.00 65.88  ? 6   GLN C CA  1 
ATOM   3485 C  C   . GLN C 3 6   ? 139.799 144.090 107.745 1.00 65.88  ? 6   GLN C C   1 
ATOM   3486 O  O   . GLN C 3 6   ? 140.869 143.743 108.253 1.00 65.88  ? 6   GLN C O   1 
ATOM   3487 C  CB  . GLN C 3 6   ? 138.297 143.076 105.997 1.00 65.88  ? 6   GLN C CB  1 
ATOM   3488 C  CG  . GLN C 3 6   ? 137.514 141.854 105.541 1.00 65.88  ? 6   GLN C CG  1 
ATOM   3489 C  CD  . GLN C 3 6   ? 136.120 141.805 106.134 1.00 65.88  ? 6   GLN C CD  1 
ATOM   3490 O  OE1 . GLN C 3 6   ? 135.764 140.868 106.846 1.00 65.88  ? 6   GLN C OE1 1 
ATOM   3491 N  NE2 . GLN C 3 6   ? 135.321 142.818 105.834 1.00 65.88  ? 6   GLN C NE2 1 
ATOM   3492 N  N   . SER C 3 7   ? 139.520 145.364 107.455 1.00 68.38  ? 7   SER C N   1 
ATOM   3493 C  CA  . SER C 3 7   ? 140.501 146.439 107.586 1.00 68.38  ? 7   SER C CA  1 
ATOM   3494 C  C   . SER C 3 7   ? 139.929 147.769 107.114 1.00 68.38  ? 7   SER C C   1 
ATOM   3495 O  O   . SER C 3 7   ? 139.344 148.522 107.900 1.00 68.38  ? 7   SER C O   1 
ATOM   3496 C  CB  . SER C 3 7   ? 141.772 146.132 106.788 1.00 68.38  ? 7   SER C CB  1 
ATOM   3497 O  OG  . SER C 3 7   ? 142.621 145.244 107.495 1.00 68.38  ? 7   SER C OG  1 
ATOM   3498 N  N   . GLY C 3 8   ? 140.097 148.059 105.826 1.00 71.96  ? 8   GLY C N   1 
ATOM   3499 C  CA  . GLY C 3 8   ? 139.672 149.318 105.247 1.00 71.96  ? 8   GLY C CA  1 
ATOM   3500 C  C   . GLY C 3 8   ? 140.295 149.545 103.885 1.00 71.96  ? 8   GLY C C   1 
ATOM   3501 O  O   . GLY C 3 8   ? 141.043 148.694 103.396 1.00 71.96  ? 8   GLY C O   1 
ATOM   3502 N  N   . ALA C 3 9   ? 140.010 150.689 103.268 1.00 73.58  ? 9   ALA C N   1 
ATOM   3503 C  CA  . ALA C 3 9   ? 140.492 150.947 101.921 1.00 73.58  ? 9   ALA C CA  1 
ATOM   3504 C  C   . ALA C 3 9   ? 142.015 151.089 101.911 1.00 73.58  ? 9   ALA C C   1 
ATOM   3505 O  O   . ALA C 3 9   ? 142.656 151.323 102.938 1.00 73.58  ? 9   ALA C O   1 
ATOM   3506 C  CB  . ALA C 3 9   ? 139.837 152.204 101.351 1.00 73.58  ? 9   ALA C CB  1 
ATOM   3507 N  N   . GLU C 3 10  ? 142.594 150.941 100.720 1.00 77.71  ? 10  GLU C N   1 
ATOM   3508 C  CA  . GLU C 3 10  ? 144.036 151.056 100.562 1.00 77.71  ? 10  GLU C CA  1 
ATOM   3509 C  C   . GLU C 3 10  ? 144.370 151.281 99.095  1.00 77.71  ? 10  GLU C C   1 
ATOM   3510 O  O   . GLU C 3 10  ? 143.691 150.755 98.207  1.00 77.71  ? 10  GLU C O   1 
ATOM   3511 C  CB  . GLU C 3 10  ? 144.758 149.807 101.086 1.00 77.71  ? 10  GLU C CB  1 
ATOM   3512 C  CG  . GLU C 3 10  ? 144.178 148.491 100.599 1.00 77.71  ? 10  GLU C CG  1 
ATOM   3513 C  CD  . GLU C 3 10  ? 144.781 147.295 101.311 1.00 77.71  ? 10  GLU C CD  1 
ATOM   3514 O  OE1 . GLU C 3 10  ? 145.712 147.492 102.119 1.00 77.71  ? 10  GLU C OE1 1 
ATOM   3515 O  OE2 . GLU C 3 10  ? 144.325 146.159 101.064 1.00 77.71  ? 10  GLU C OE2 1 
ATOM   3516 N  N   . VAL C 3 11  ? 145.417 152.068 98.856  1.00 83.95  ? 11  VAL C N   1 
ATOM   3517 C  CA  . VAL C 3 11  ? 145.934 152.340 97.521  1.00 83.95  ? 11  VAL C CA  1 
ATOM   3518 C  C   . VAL C 3 11  ? 147.384 151.882 97.480  1.00 83.95  ? 11  VAL C C   1 
ATOM   3519 O  O   . VAL C 3 11  ? 148.180 152.248 98.353  1.00 83.95  ? 11  VAL C O   1 
ATOM   3520 C  CB  . VAL C 3 11  ? 145.818 153.831 97.156  1.00 83.95  ? 11  VAL C CB  1 
ATOM   3521 C  CG1 . VAL C 3 11  ? 146.302 154.070 95.734  1.00 83.95  ? 11  VAL C CG1 1 
ATOM   3522 C  CG2 . VAL C 3 11  ? 144.383 154.310 97.324  1.00 83.95  ? 11  VAL C CG2 1 
ATOM   3523 N  N   . LYS C 3 12  ? 147.724 151.085 96.470  1.00 86.26  ? 12  LYS C N   1 
ATOM   3524 C  CA  . LYS C 3 12  ? 149.052 150.505 96.346  1.00 86.26  ? 12  LYS C CA  1 
ATOM   3525 C  C   . LYS C 3 12  ? 149.604 150.744 94.949  1.00 86.26  ? 12  LYS C C   1 
ATOM   3526 O  O   . LYS C 3 12  ? 148.856 150.826 93.971  1.00 86.26  ? 12  LYS C O   1 
ATOM   3527 C  CB  . LYS C 3 12  ? 149.037 148.999 96.646  1.00 86.26  ? 12  LYS C CB  1 
ATOM   3528 C  CG  . LYS C 3 12  ? 148.762 148.656 98.101  1.00 86.26  ? 12  LYS C CG  1 
ATOM   3529 C  CD  . LYS C 3 12  ? 149.926 149.056 98.992  1.00 86.26  ? 12  LYS C CD  1 
ATOM   3530 C  CE  . LYS C 3 12  ? 149.736 148.545 100.411 1.00 86.26  ? 12  LYS C CE  1 
ATOM   3531 N  NZ  . LYS C 3 12  ? 150.745 149.114 101.346 1.00 86.26  ? 12  LYS C NZ  1 
ATOM   3532 N  N   . LYS C 3 13  ? 150.930 150.855 94.869  1.00 87.97  ? 13  LYS C N   1 
ATOM   3533 C  CA  . LYS C 3 13  ? 151.619 151.022 93.600  1.00 87.97  ? 13  LYS C CA  1 
ATOM   3534 C  C   . LYS C 3 13  ? 151.623 149.711 92.816  1.00 87.97  ? 13  LYS C C   1 
ATOM   3535 O  O   . LYS C 3 13  ? 151.575 148.627 93.405  1.00 87.97  ? 13  LYS C O   1 
ATOM   3536 C  CB  . LYS C 3 13  ? 153.054 151.486 93.833  1.00 87.97  ? 13  LYS C CB  1 
ATOM   3537 C  CG  . LYS C 3 13  ? 153.175 152.921 94.319  1.00 87.97  ? 13  LYS C CG  1 
ATOM   3538 C  CD  . LYS C 3 13  ? 154.630 153.358 94.382  1.00 87.97  ? 13  LYS C CD  1 
ATOM   3539 C  CE  . LYS C 3 13  ? 154.755 154.810 94.812  1.00 87.97  ? 13  LYS C CE  1 
ATOM   3540 N  NZ  . LYS C 3 13  ? 156.172 155.266 94.827  1.00 87.97  ? 13  LYS C NZ  1 
ATOM   3541 N  N   . PRO C 3 14  ? 151.669 149.782 91.487  1.00 86.63  ? 14  PRO C N   1 
ATOM   3542 C  CA  . PRO C 3 14  ? 151.736 148.553 90.690  1.00 86.63  ? 14  PRO C CA  1 
ATOM   3543 C  C   . PRO C 3 14  ? 153.032 147.795 90.932  1.00 86.63  ? 14  PRO C C   1 
ATOM   3544 O  O   . PRO C 3 14  ? 154.088 148.381 91.184  1.00 86.63  ? 14  PRO C O   1 
ATOM   3545 C  CB  . PRO C 3 14  ? 151.651 149.059 89.243  1.00 86.63  ? 14  PRO C CB  1 
ATOM   3546 C  CG  . PRO C 3 14  ? 151.101 150.448 89.345  1.00 86.63  ? 14  PRO C CG  1 
ATOM   3547 C  CD  . PRO C 3 14  ? 151.608 150.985 90.642  1.00 86.63  ? 14  PRO C CD  1 
ATOM   3548 N  N   . GLY C 3 15  ? 152.938 146.469 90.851  1.00 85.45  ? 15  GLY C N   1 
ATOM   3549 C  CA  . GLY C 3 15  ? 154.086 145.606 91.026  1.00 85.45  ? 15  GLY C CA  1 
ATOM   3550 C  C   . GLY C 3 15  ? 154.420 145.250 92.458  1.00 85.45  ? 15  GLY C C   1 
ATOM   3551 O  O   . GLY C 3 15  ? 155.343 144.457 92.681  1.00 85.45  ? 15  GLY C O   1 
ATOM   3552 N  N   . SER C 3 16  ? 153.705 145.804 93.432  1.00 83.06  ? 16  SER C N   1 
ATOM   3553 C  CA  . SER C 3 16  ? 153.970 145.532 94.836  1.00 83.06  ? 16  SER C CA  1 
ATOM   3554 C  C   . SER C 3 16  ? 153.151 144.324 95.290  1.00 83.06  ? 16  SER C C   1 
ATOM   3555 O  O   . SER C 3 16  ? 152.538 143.619 94.484  1.00 83.06  ? 16  SER C O   1 
ATOM   3556 C  CB  . SER C 3 16  ? 153.673 146.771 95.677  1.00 83.06  ? 16  SER C CB  1 
ATOM   3557 O  OG  . SER C 3 16  ? 152.280 147.021 95.743  1.00 83.06  ? 16  SER C OG  1 
ATOM   3558 N  N   . SER C 3 17  ? 153.136 144.074 96.596  1.00 78.46  ? 17  SER C N   1 
ATOM   3559 C  CA  . SER C 3 17  ? 152.387 142.976 97.188  1.00 78.46  ? 17  SER C CA  1 
ATOM   3560 C  C   . SER C 3 17  ? 151.382 143.531 98.185  1.00 78.46  ? 17  SER C C   1 
ATOM   3561 O  O   . SER C 3 17  ? 151.718 144.397 98.999  1.00 78.46  ? 17  SER C O   1 
ATOM   3562 C  CB  . SER C 3 17  ? 153.321 141.980 97.882  1.00 78.46  ? 17  SER C CB  1 
ATOM   3563 O  OG  . SER C 3 17  ? 153.986 141.159 96.938  1.00 78.46  ? 17  SER C OG  1 
ATOM   3564 N  N   . VAL C 3 18  ? 150.151 143.031 98.123  1.00 74.68  ? 18  VAL C N   1 
ATOM   3565 C  CA  . VAL C 3 18  ? 149.081 143.505 98.991  1.00 74.68  ? 18  VAL C CA  1 
ATOM   3566 C  C   . VAL C 3 18  ? 148.708 142.395 99.964  1.00 74.68  ? 18  VAL C C   1 
ATOM   3567 O  O   . VAL C 3 18  ? 148.700 141.210 99.616  1.00 74.68  ? 18  VAL C O   1 
ATOM   3568 C  CB  . VAL C 3 18  ? 147.849 143.986 98.189  1.00 74.68  ? 18  VAL C CB  1 
ATOM   3569 C  CG1 . VAL C 3 18  ? 147.133 142.819 97.523  1.00 74.68  ? 18  VAL C CG1 1 
ATOM   3570 C  CG2 . VAL C 3 18  ? 146.896 144.763 99.086  1.00 74.68  ? 18  VAL C CG2 1 
ATOM   3571 N  N   . LYS C 3 19  ? 148.425 142.791 101.204 1.00 69.00  ? 19  LYS C N   1 
ATOM   3572 C  CA  . LYS C 3 19  ? 148.085 141.855 102.271 1.00 69.00  ? 19  LYS C CA  1 
ATOM   3573 C  C   . LYS C 3 19  ? 146.836 142.357 102.978 1.00 69.00  ? 19  LYS C C   1 
ATOM   3574 O  O   . LYS C 3 19  ? 146.785 143.513 103.408 1.00 69.00  ? 19  LYS C O   1 
ATOM   3575 C  CB  . LYS C 3 19  ? 149.245 141.704 103.260 1.00 69.00  ? 19  LYS C CB  1 
ATOM   3576 C  CG  . LYS C 3 19  ? 149.153 140.477 104.149 1.00 69.00  ? 19  LYS C CG  1 
ATOM   3577 C  CD  . LYS C 3 19  ? 150.396 140.334 105.014 1.00 69.00  ? 19  LYS C CD  1 
ATOM   3578 C  CE  . LYS C 3 19  ? 150.453 138.969 105.681 1.00 69.00  ? 19  LYS C CE  1 
ATOM   3579 N  NZ  . LYS C 3 19  ? 151.671 138.811 106.524 1.00 69.00  ? 19  LYS C NZ  1 
ATOM   3580 N  N   . VAL C 3 20  ? 145.837 141.488 103.097 1.00 65.44  ? 20  VAL C N   1 
ATOM   3581 C  CA  . VAL C 3 20  ? 144.547 141.820 103.688 1.00 65.44  ? 20  VAL C CA  1 
ATOM   3582 C  C   . VAL C 3 20  ? 144.267 140.826 104.808 1.00 65.44  ? 20  VAL C C   1 
ATOM   3583 O  O   . VAL C 3 20  ? 144.662 139.657 104.727 1.00 65.44  ? 20  VAL C O   1 
ATOM   3584 C  CB  . VAL C 3 20  ? 143.422 141.802 102.630 1.00 65.44  ? 20  VAL C CB  1 
ATOM   3585 C  CG1 . VAL C 3 20  ? 142.078 142.156 103.250 1.00 65.44  ? 20  VAL C CG1 1 
ATOM   3586 C  CG2 . VAL C 3 20  ? 143.751 142.750 101.487 1.00 65.44  ? 20  VAL C CG2 1 
ATOM   3587 N  N   . SER C 3 21  ? 143.588 141.294 105.853 1.00 64.25  ? 21  SER C N   1 
ATOM   3588 C  CA  . SER C 3 21  ? 143.349 140.518 107.060 1.00 64.25  ? 21  SER C CA  1 
ATOM   3589 C  C   . SER C 3 21  ? 141.864 140.222 107.220 1.00 64.25  ? 21  SER C C   1 
ATOM   3590 O  O   . SER C 3 21  ? 141.015 141.016 106.807 1.00 64.25  ? 21  SER C O   1 
ATOM   3591 C  CB  . SER C 3 21  ? 143.862 141.265 108.294 1.00 64.25  ? 21  SER C CB  1 
ATOM   3592 O  OG  . SER C 3 21  ? 143.766 140.462 109.455 1.00 64.25  ? 21  SER C OG  1 
ATOM   3593 N  N   . CYS C 3 22  ? 141.562 139.068 107.811 1.00 64.78  ? 22  CYS C N   1 
ATOM   3594 C  CA  . CYS C 3 22  ? 140.205 138.694 108.191 1.00 64.78  ? 22  CYS C CA  1 
ATOM   3595 C  C   . CYS C 3 22  ? 140.230 138.105 109.594 1.00 64.78  ? 22  CYS C C   1 
ATOM   3596 O  O   . CYS C 3 22  ? 140.902 137.097 109.834 1.00 64.78  ? 22  CYS C O   1 
ATOM   3597 C  CB  . CYS C 3 22  ? 139.610 137.688 107.201 1.00 64.78  ? 22  CYS C CB  1 
ATOM   3598 S  SG  . CYS C 3 22  ? 137.909 137.180 107.557 1.00 64.78  ? 22  CYS C SG  1 
ATOM   3599 N  N   . LYS C 3 23  ? 139.506 138.732 110.517 1.00 66.47  ? 23  LYS C N   1 
ATOM   3600 C  CA  . LYS C 3 23  ? 139.462 138.301 111.908 1.00 66.47  ? 23  LYS C CA  1 
ATOM   3601 C  C   . LYS C 3 23  ? 138.036 137.924 112.281 1.00 66.47  ? 23  LYS C C   1 
ATOM   3602 O  O   . LYS C 3 23  ? 137.098 138.678 112.001 1.00 66.47  ? 23  LYS C O   1 
ATOM   3603 C  CB  . LYS C 3 23  ? 139.984 139.397 112.841 1.00 66.47  ? 23  LYS C CB  1 
ATOM   3604 C  CG  . LYS C 3 23  ? 139.744 139.121 114.316 1.00 66.47  ? 23  LYS C CG  1 
ATOM   3605 C  CD  . LYS C 3 23  ? 140.287 140.241 115.185 1.00 66.47  ? 23  LYS C CD  1 
ATOM   3606 C  CE  . LYS C 3 23  ? 140.055 139.955 116.660 1.00 66.47  ? 23  LYS C CE  1 
ATOM   3607 N  NZ  . LYS C 3 23  ? 140.665 140.997 117.531 1.00 66.47  ? 23  LYS C NZ  1 
ATOM   3608 N  N   . ALA C 3 24  ? 137.878 136.765 112.912 1.00 64.95  ? 24  ALA C N   1 
ATOM   3609 C  CA  . ALA C 3 24  ? 136.565 136.298 113.323 1.00 64.95  ? 24  ALA C CA  1 
ATOM   3610 C  C   . ALA C 3 24  ? 136.129 136.980 114.616 1.00 64.95  ? 24  ALA C C   1 
ATOM   3611 O  O   . ALA C 3 24  ? 136.931 137.582 115.335 1.00 64.95  ? 24  ALA C O   1 
ATOM   3612 C  CB  . ALA C 3 24  ? 136.563 134.782 113.507 1.00 64.95  ? 24  ALA C CB  1 
ATOM   3613 N  N   . SER C 3 25  ? 134.828 136.883 114.901 1.00 69.02  ? 25  SER C N   1 
ATOM   3614 C  CA  . SER C 3 25  ? 134.304 137.429 116.149 1.00 69.02  ? 25  SER C CA  1 
ATOM   3615 C  C   . SER C 3 25  ? 134.919 136.727 117.352 1.00 69.02  ? 25  SER C C   1 
ATOM   3616 O  O   . SER C 3 25  ? 135.298 137.375 118.334 1.00 69.02  ? 25  SER C O   1 
ATOM   3617 C  CB  . SER C 3 25  ? 132.781 137.309 116.177 1.00 69.02  ? 25  SER C CB  1 
ATOM   3618 O  OG  . SER C 3 25  ? 132.361 136.028 115.740 1.00 69.02  ? 25  SER C OG  1 
ATOM   3619 N  N   . GLY C 3 26  ? 135.026 135.401 117.293 1.00 70.57  ? 26  GLY C N   1 
ATOM   3620 C  CA  . GLY C 3 26  ? 135.711 134.640 118.310 1.00 70.57  ? 26  GLY C CA  1 
ATOM   3621 C  C   . GLY C 3 26  ? 137.110 134.258 117.863 1.00 70.57  ? 26  GLY C C   1 
ATOM   3622 O  O   . GLY C 3 26  ? 137.361 134.005 116.687 1.00 70.57  ? 26  GLY C O   1 
ATOM   3623 N  N   . GLY C 3 27  ? 138.027 134.218 118.825 1.00 69.20  ? 27  GLY C N   1 
ATOM   3624 C  CA  . GLY C 3 27  ? 139.413 133.928 118.520 1.00 69.20  ? 27  GLY C CA  1 
ATOM   3625 C  C   . GLY C 3 27  ? 139.706 132.455 118.330 1.00 69.20  ? 27  GLY C C   1 
ATOM   3626 O  O   . GLY C 3 27  ? 140.660 131.929 118.911 1.00 69.20  ? 27  GLY C O   1 
ATOM   3627 N  N   . THR C 3 28  ? 138.896 131.774 117.520 1.00 67.03  ? 28  THR C N   1 
ATOM   3628 C  CA  . THR C 3 28  ? 139.072 130.348 117.274 1.00 67.03  ? 28  THR C CA  1 
ATOM   3629 C  C   . THR C 3 28  ? 138.491 129.981 115.918 1.00 67.03  ? 28  THR C C   1 
ATOM   3630 O  O   . THR C 3 28  ? 137.341 130.317 115.620 1.00 67.03  ? 28  THR C O   1 
ATOM   3631 C  CB  . THR C 3 28  ? 138.406 129.504 118.368 1.00 67.03  ? 28  THR C CB  1 
ATOM   3632 O  OG1 . THR C 3 28  ? 138.887 129.914 119.654 1.00 67.03  ? 28  THR C OG1 1 
ATOM   3633 C  CG2 . THR C 3 28  ? 138.714 128.028 118.165 1.00 67.03  ? 28  THR C CG2 1 
ATOM   3634 N  N   . PHE C 3 29  ? 139.290 129.296 115.104 1.00 67.65  ? 29  PHE C N   1 
ATOM   3635 C  CA  . PHE C 3 29  ? 138.853 128.699 113.844 1.00 67.65  ? 29  PHE C CA  1 
ATOM   3636 C  C   . PHE C 3 29  ? 138.726 127.199 114.094 1.00 67.65  ? 29  PHE C C   1 
ATOM   3637 O  O   . PHE C 3 29  ? 139.657 126.435 113.829 1.00 67.65  ? 29  PHE C O   1 
ATOM   3638 C  CB  . PHE C 3 29  ? 139.836 129.001 112.716 1.00 67.65  ? 29  PHE C CB  1 
ATOM   3639 C  CG  . PHE C 3 29  ? 139.720 130.389 112.161 1.00 67.65  ? 29  PHE C CG  1 
ATOM   3640 C  CD1 . PHE C 3 29  ? 138.544 131.107 112.291 1.00 67.65  ? 29  PHE C CD1 1 
ATOM   3641 C  CD2 . PHE C 3 29  ? 140.789 130.978 111.507 1.00 67.65  ? 29  PHE C CD2 1 
ATOM   3642 C  CE1 . PHE C 3 29  ? 138.437 132.384 111.776 1.00 67.65  ? 29  PHE C CE1 1 
ATOM   3643 C  CE2 . PHE C 3 29  ? 140.688 132.255 110.992 1.00 67.65  ? 29  PHE C CE2 1 
ATOM   3644 C  CZ  . PHE C 3 29  ? 139.510 132.959 111.127 1.00 67.65  ? 29  PHE C CZ  1 
ATOM   3645 N  N   . SER C 3 30  ? 137.570 126.778 114.605 1.00 64.88  ? 30  SER C N   1 
ATOM   3646 C  CA  . SER C 3 30  ? 137.380 125.387 115.007 1.00 64.88  ? 30  SER C CA  1 
ATOM   3647 C  C   . SER C 3 30  ? 137.227 124.467 113.800 1.00 64.88  ? 30  SER C C   1 
ATOM   3648 O  O   . SER C 3 30  ? 138.054 123.576 113.579 1.00 64.88  ? 30  SER C O   1 
ATOM   3649 C  CB  . SER C 3 30  ? 136.160 125.271 115.929 1.00 64.88  ? 30  SER C CB  1 
ATOM   3650 O  OG  . SER C 3 30  ? 136.397 125.902 117.174 1.00 64.88  ? 30  SER C OG  1 
ATOM   3651 N  N   . SER C 3 31  ? 136.173 124.674 113.011 1.00 59.56  ? 31  SER C N   1 
ATOM   3652 C  CA  . SER C 3 31  ? 135.931 123.881 111.814 1.00 59.56  ? 31  SER C CA  1 
ATOM   3653 C  C   . SER C 3 31  ? 135.426 124.733 110.658 1.00 59.56  ? 31  SER C C   1 
ATOM   3654 O  O   . SER C 3 31  ? 134.745 124.208 109.769 1.00 59.56  ? 31  SER C O   1 
ATOM   3655 C  CB  . SER C 3 31  ? 134.934 122.756 112.105 1.00 59.56  ? 31  SER C CB  1 
ATOM   3656 O  OG  . SER C 3 31  ? 133.599 123.222 112.006 1.00 59.56  ? 31  SER C OG  1 
ATOM   3657 N  N   . TYR C 3 32  ? 135.739 126.024 110.646 1.00 61.83  ? 32  TYR C N   1 
ATOM   3658 C  CA  . TYR C 3 32  ? 135.221 126.940 109.642 1.00 61.83  ? 32  TYR C CA  1 
ATOM   3659 C  C   . TYR C 3 32  ? 136.216 127.089 108.499 1.00 61.83  ? 32  TYR C C   1 
ATOM   3660 O  O   . TYR C 3 32  ? 137.415 127.275 108.728 1.00 61.83  ? 32  TYR C O   1 
ATOM   3661 C  CB  . TYR C 3 32  ? 134.923 128.303 110.266 1.00 61.83  ? 32  TYR C CB  1 
ATOM   3662 C  CG  . TYR C 3 32  ? 133.630 128.352 111.048 1.00 61.83  ? 32  TYR C CG  1 
ATOM   3663 C  CD1 . TYR C 3 32  ? 133.596 128.851 112.343 1.00 61.83  ? 32  TYR C CD1 1 
ATOM   3664 C  CD2 . TYR C 3 32  ? 132.441 127.908 110.486 1.00 61.83  ? 32  TYR C CD2 1 
ATOM   3665 C  CE1 . TYR C 3 32  ? 132.415 128.900 113.058 1.00 61.83  ? 32  TYR C CE1 1 
ATOM   3666 C  CE2 . TYR C 3 32  ? 131.256 127.954 111.194 1.00 61.83  ? 32  TYR C CE2 1 
ATOM   3667 C  CZ  . TYR C 3 32  ? 131.248 128.451 112.479 1.00 61.83  ? 32  TYR C CZ  1 
ATOM   3668 O  OH  . TYR C 3 32  ? 130.070 128.498 113.187 1.00 61.83  ? 32  TYR C OH  1 
ATOM   3669 N  N   . ALA C 3 33  ? 135.711 127.001 107.274 1.00 58.66  ? 33  ALA C N   1 
ATOM   3670 C  CA  . ALA C 3 33  ? 136.509 127.236 106.081 1.00 58.66  ? 33  ALA C CA  1 
ATOM   3671 C  C   . ALA C 3 33  ? 136.401 128.703 105.691 1.00 58.66  ? 33  ALA C C   1 
ATOM   3672 O  O   . ALA C 3 33  ? 135.293 129.238 105.564 1.00 58.66  ? 33  ALA C O   1 
ATOM   3673 C  CB  . ALA C 3 33  ? 136.048 126.342 104.930 1.00 58.66  ? 33  ALA C CB  1 
ATOM   3674 N  N   . ILE C 3 34  ? 137.550 129.348 105.512 1.00 59.61  ? 34  ILE C N   1 
ATOM   3675 C  CA  . ILE C 3 34  ? 137.617 130.777 105.231 1.00 59.61  ? 34  ILE C CA  1 
ATOM   3676 C  C   . ILE C 3 34  ? 137.919 130.961 103.752 1.00 59.61  ? 34  ILE C C   1 
ATOM   3677 O  O   . ILE C 3 34  ? 138.983 130.555 103.271 1.00 59.61  ? 34  ILE C O   1 
ATOM   3678 C  CB  . ILE C 3 34  ? 138.677 131.470 106.101 1.00 59.61  ? 34  ILE C CB  1 
ATOM   3679 C  CG1 . ILE C 3 34  ? 138.226 131.508 107.562 1.00 59.61  ? 34  ILE C CG1 1 
ATOM   3680 C  CG2 . ILE C 3 34  ? 138.949 132.876 105.591 1.00 59.61  ? 34  ILE C CG2 1 
ATOM   3681 C  CD1 . ILE C 3 34  ? 136.891 132.185 107.770 1.00 59.61  ? 34  ILE C CD1 1 
ATOM   3682 N  N   . SER C 3 35  ? 136.987 131.570 103.031 1.00 61.59  ? 35  SER C N   1 
ATOM   3683 C  CA  . SER C 3 35  ? 137.143 131.838 101.612 1.00 61.59  ? 35  SER C CA  1 
ATOM   3684 C  C   . SER C 3 35  ? 137.400 133.320 101.381 1.00 61.59  ? 35  SER C C   1 
ATOM   3685 O  O   . SER C 3 35  ? 137.037 134.168 102.199 1.00 61.59  ? 35  SER C O   1 
ATOM   3686 C  CB  . SER C 3 35  ? 135.903 131.401 100.834 1.00 61.59  ? 35  SER C CB  1 
ATOM   3687 O  OG  . SER C 3 35  ? 135.487 130.107 101.227 1.00 61.59  ? 35  SER C OG  1 
ATOM   3688 N  N   . TRP C 3 36  ? 138.035 133.624 100.255 1.00 61.97  ? 36  TRP C N   1 
ATOM   3689 C  CA  . TRP C 3 36  ? 138.334 134.994 99.869  1.00 61.97  ? 36  TRP C CA  1 
ATOM   3690 C  C   . TRP C 3 36  ? 137.821 135.222 98.458  1.00 61.97  ? 36  TRP C C   1 
ATOM   3691 O  O   . TRP C 3 36  ? 138.199 134.493 97.531  1.00 61.97  ? 36  TRP C O   1 
ATOM   3692 C  CB  . TRP C 3 36  ? 139.834 135.274 99.951  1.00 61.97  ? 36  TRP C CB  1 
ATOM   3693 C  CG  . TRP C 3 36  ? 140.326 135.378 101.355 1.00 61.97  ? 36  TRP C CG  1 
ATOM   3694 C  CD1 . TRP C 3 36  ? 140.532 134.351 102.227 1.00 61.97  ? 36  TRP C CD1 1 
ATOM   3695 C  CD2 . TRP C 3 36  ? 140.646 136.578 102.066 1.00 61.97  ? 36  TRP C CD2 1 
ATOM   3696 N  NE1 . TRP C 3 36  ? 140.978 134.835 103.432 1.00 61.97  ? 36  TRP C NE1 1 
ATOM   3697 C  CE2 . TRP C 3 36  ? 141.055 136.201 103.359 1.00 61.97  ? 36  TRP C CE2 1 
ATOM   3698 C  CE3 . TRP C 3 36  ? 140.633 137.934 101.732 1.00 61.97  ? 36  TRP C CE3 1 
ATOM   3699 C  CZ2 . TRP C 3 36  ? 141.449 137.130 104.317 1.00 61.97  ? 36  TRP C CZ2 1 
ATOM   3700 C  CZ3 . TRP C 3 36  ? 141.024 138.854 102.683 1.00 61.97  ? 36  TRP C CZ3 1 
ATOM   3701 C  CH2 . TRP C 3 36  ? 141.425 138.450 103.961 1.00 61.97  ? 36  TRP C CH2 1 
ATOM   3702 N  N   . VAL C 3 37  ? 136.971 136.239 98.305  1.00 59.59  ? 37  VAL C N   1 
ATOM   3703 C  CA  . VAL C 3 37  ? 136.273 136.537 97.062  1.00 59.59  ? 37  VAL C CA  1 
ATOM   3704 C  C   . VAL C 3 37  ? 136.642 137.950 96.629  1.00 59.59  ? 37  VAL C C   1 
ATOM   3705 O  O   . VAL C 3 37  ? 136.969 138.806 97.457  1.00 59.59  ? 37  VAL C O   1 
ATOM   3706 C  CB  . VAL C 3 37  ? 134.742 136.391 97.233  1.00 59.59  ? 37  VAL C CB  1 
ATOM   3707 C  CG1 . VAL C 3 37  ? 134.017 136.547 95.904  1.00 59.59  ? 37  VAL C CG1 1 
ATOM   3708 C  CG2 . VAL C 3 37  ? 134.402 135.056 97.877  1.00 59.59  ? 37  VAL C CG2 1 
ATOM   3709 N  N   . ARG C 3 38  ? 136.600 138.189 95.320  1.00 60.72  ? 38  ARG C N   1 
ATOM   3710 C  CA  . ARG C 3 38  ? 136.899 139.499 94.762  1.00 60.72  ? 38  ARG C CA  1 
ATOM   3711 C  C   . ARG C 3 38  ? 135.729 139.961 93.908  1.00 60.72  ? 38  ARG C C   1 
ATOM   3712 O  O   . ARG C 3 38  ? 135.078 139.158 93.235  1.00 60.72  ? 38  ARG C O   1 
ATOM   3713 C  CB  . ARG C 3 38  ? 138.178 139.476 93.917  1.00 60.72  ? 38  ARG C CB  1 
ATOM   3714 C  CG  . ARG C 3 38  ? 138.648 140.847 93.484  1.00 60.72  ? 38  ARG C CG  1 
ATOM   3715 C  CD  . ARG C 3 38  ? 139.892 140.769 92.623  1.00 60.72  ? 38  ARG C CD  1 
ATOM   3716 N  NE  . ARG C 3 38  ? 139.580 140.356 91.261  1.00 60.72  ? 38  ARG C NE  1 
ATOM   3717 C  CZ  . ARG C 3 38  ? 140.481 140.201 90.301  1.00 60.72  ? 38  ARG C CZ  1 
ATOM   3718 N  NH1 . ARG C 3 38  ? 141.766 140.422 90.519  1.00 60.72  ? 38  ARG C NH1 1 
ATOM   3719 N  NH2 . ARG C 3 38  ? 140.081 139.816 89.093  1.00 60.72  ? 38  ARG C NH2 1 
ATOM   3720 N  N   . GLN C 3 39  ? 135.466 141.267 93.941  1.00 63.06  ? 39  GLN C N   1 
ATOM   3721 C  CA  . GLN C 3 39  ? 134.422 141.867 93.119  1.00 63.06  ? 39  GLN C CA  1 
ATOM   3722 C  C   . GLN C 3 39  ? 134.986 143.090 92.416  1.00 63.06  ? 39  GLN C C   1 
ATOM   3723 O  O   . GLN C 3 39  ? 135.481 144.013 93.070  1.00 63.06  ? 39  GLN C O   1 
ATOM   3724 C  CB  . GLN C 3 39  ? 133.197 142.252 93.955  1.00 63.06  ? 39  GLN C CB  1 
ATOM   3725 C  CG  . GLN C 3 39  ? 132.144 143.011 93.163  1.00 63.06  ? 39  GLN C CG  1 
ATOM   3726 C  CD  . GLN C 3 39  ? 130.900 143.319 93.970  1.00 63.06  ? 39  GLN C CD  1 
ATOM   3727 O  OE1 . GLN C 3 39  ? 129.811 143.464 93.416  1.00 63.06  ? 39  GLN C OE1 1 
ATOM   3728 N  NE2 . GLN C 3 39  ? 131.055 143.422 95.285  1.00 63.06  ? 39  GLN C NE2 1 
ATOM   3729 N  N   . ALA C 3 40  ? 134.914 143.088 91.088  1.00 69.09  ? 40  ALA C N   1 
ATOM   3730 C  CA  . ALA C 3 40  ? 135.276 144.262 90.316  1.00 69.09  ? 40  ALA C CA  1 
ATOM   3731 C  C   . ALA C 3 40  ? 134.179 145.320 90.442  1.00 69.09  ? 40  ALA C C   1 
ATOM   3732 O  O   . ALA C 3 40  ? 133.022 144.992 90.717  1.00 69.09  ? 40  ALA C O   1 
ATOM   3733 C  CB  . ALA C 3 40  ? 135.488 143.885 88.852  1.00 69.09  ? 40  ALA C CB  1 
ATOM   3734 N  N   . PRO C 3 41  ? 134.512 146.603 90.243  1.00 69.00  ? 41  PRO C N   1 
ATOM   3735 C  CA  . PRO C 3 41  ? 133.511 147.654 90.474  1.00 69.00  ? 41  PRO C CA  1 
ATOM   3736 C  C   . PRO C 3 41  ? 132.403 147.669 89.432  1.00 69.00  ? 41  PRO C C   1 
ATOM   3737 O  O   . PRO C 3 41  ? 132.599 148.142 88.309  1.00 69.00  ? 41  PRO C O   1 
ATOM   3738 C  CB  . PRO C 3 41  ? 134.342 148.944 90.422  1.00 69.00  ? 41  PRO C CB  1 
ATOM   3739 C  CG  . PRO C 3 41  ? 135.526 148.594 89.591  1.00 69.00  ? 41  PRO C CG  1 
ATOM   3740 C  CD  . PRO C 3 41  ? 135.834 147.164 89.909  1.00 69.00  ? 41  PRO C CD  1 
ATOM   3741 N  N   . GLY C 3 42  ? 131.223 147.181 89.812  1.00 70.89  ? 42  GLY C N   1 
ATOM   3742 C  CA  . GLY C 3 42  ? 130.065 147.220 88.942  1.00 70.89  ? 42  GLY C CA  1 
ATOM   3743 C  C   . GLY C 3 42  ? 129.972 146.126 87.905  1.00 70.89  ? 42  GLY C C   1 
ATOM   3744 O  O   . GLY C 3 42  ? 129.172 146.248 86.972  1.00 70.89  ? 42  GLY C O   1 
ATOM   3745 N  N   . GLN C 3 43  ? 130.759 145.055 88.029  1.00 70.54  ? 43  GLN C N   1 
ATOM   3746 C  CA  . GLN C 3 43  ? 130.665 143.924 87.111  1.00 70.54  ? 43  GLN C CA  1 
ATOM   3747 C  C   . GLN C 3 43  ? 130.153 142.662 87.794  1.00 70.54  ? 43  GLN C C   1 
ATOM   3748 O  O   . GLN C 3 43  ? 129.136 142.104 87.371  1.00 70.54  ? 43  GLN C O   1 
ATOM   3749 C  CB  . GLN C 3 43  ? 132.024 143.650 86.453  1.00 70.54  ? 43  GLN C CB  1 
ATOM   3750 C  CG  . GLN C 3 43  ? 132.442 144.707 85.458  1.00 70.54  ? 43  GLN C CG  1 
ATOM   3751 C  CD  . GLN C 3 43  ? 133.106 145.892 86.124  1.00 70.54  ? 43  GLN C CD  1 
ATOM   3752 O  OE1 . GLN C 3 43  ? 133.556 145.806 87.264  1.00 70.54  ? 43  GLN C OE1 1 
ATOM   3753 N  NE2 . GLN C 3 43  ? 133.169 147.008 85.414  1.00 70.54  ? 43  GLN C NE2 1 
ATOM   3754 N  N   . GLY C 3 44  ? 130.821 142.195 88.838  1.00 68.33  ? 44  GLY C N   1 
ATOM   3755 C  CA  . GLY C 3 44  ? 130.394 140.984 89.510  1.00 68.33  ? 44  GLY C CA  1 
ATOM   3756 C  C   . GLY C 3 44  ? 131.462 140.457 90.437  1.00 68.33  ? 44  GLY C C   1 
ATOM   3757 O  O   . GLY C 3 44  ? 132.530 141.046 90.607  1.00 68.33  ? 44  GLY C O   1 
ATOM   3758 N  N   . LEU C 3 45  ? 131.154 139.309 91.031  1.00 60.75  ? 45  LEU C N   1 
ATOM   3759 C  CA  . LEU C 3 45  ? 132.064 138.665 91.963  1.00 60.75  ? 45  LEU C CA  1 
ATOM   3760 C  C   . LEU C 3 45  ? 133.027 137.735 91.235  1.00 60.75  ? 45  LEU C C   1 
ATOM   3761 O  O   . LEU C 3 45  ? 132.867 137.428 90.051  1.00 60.75  ? 45  LEU C O   1 
ATOM   3762 C  CB  . LEU C 3 45  ? 131.286 137.881 93.019  1.00 60.75  ? 45  LEU C CB  1 
ATOM   3763 C  CG  . LEU C 3 45  ? 130.433 138.718 93.973  1.00 60.75  ? 45  LEU C CG  1 
ATOM   3764 C  CD1 . LEU C 3 45  ? 129.021 138.862 93.437  1.00 60.75  ? 45  LEU C CD1 1 
ATOM   3765 C  CD2 . LEU C 3 45  ? 130.419 138.107 95.374  1.00 60.75  ? 45  LEU C CD2 1 
ATOM   3766 N  N   . GLU C 3 46  ? 134.038 137.276 91.972  1.00 61.36  ? 46  GLU C N   1 
ATOM   3767 C  CA  . GLU C 3 46  ? 135.038 136.367 91.415  1.00 61.36  ? 46  GLU C CA  1 
ATOM   3768 C  C   . GLU C 3 46  ? 135.675 135.610 92.576  1.00 61.36  ? 46  GLU C C   1 
ATOM   3769 O  O   . GLU C 3 46  ? 136.409 136.197 93.378  1.00 61.36  ? 46  GLU C O   1 
ATOM   3770 C  CB  . GLU C 3 46  ? 136.085 137.120 90.605  1.00 61.36  ? 46  GLU C CB  1 
ATOM   3771 C  CG  . GLU C 3 46  ? 137.210 136.235 90.069  1.00 61.36  ? 46  GLU C CG  1 
ATOM   3772 C  CD  . GLU C 3 46  ? 138.021 136.913 88.982  1.00 61.36  ? 46  GLU C CD  1 
ATOM   3773 O  OE1 . GLU C 3 46  ? 138.298 138.120 89.117  1.00 61.36  ? 46  GLU C OE1 1 
ATOM   3774 O  OE2 . GLU C 3 46  ? 138.378 136.249 87.989  1.00 61.36  ? 46  GLU C OE2 1 
ATOM   3775 N  N   . TRP C 3 47  ? 135.400 134.311 92.650  1.00 63.13  ? 47  TRP C N   1 
ATOM   3776 C  CA  . TRP C 3 47  ? 136.000 133.486 93.686  1.00 63.13  ? 47  TRP C CA  1 
ATOM   3777 C  C   . TRP C 3 47  ? 137.505 133.405 93.482  1.00 63.13  ? 47  TRP C C   1 
ATOM   3778 O  O   . TRP C 3 47  ? 137.985 133.179 92.368  1.00 63.13  ? 47  TRP C O   1 
ATOM   3779 C  CB  . TRP C 3 47  ? 135.385 132.091 93.674  1.00 63.13  ? 47  TRP C CB  1 
ATOM   3780 C  CG  . TRP C 3 47  ? 135.723 131.298 94.882  1.00 63.13  ? 47  TRP C CG  1 
ATOM   3781 C  CD1 . TRP C 3 47  ? 135.042 131.271 96.059  1.00 63.13  ? 47  TRP C CD1 1 
ATOM   3782 C  CD2 . TRP C 3 47  ? 136.837 130.413 95.041  1.00 63.13  ? 47  TRP C CD2 1 
ATOM   3783 N  NE1 . TRP C 3 47  ? 135.656 130.417 96.941  1.00 63.13  ? 47  TRP C NE1 1 
ATOM   3784 C  CE2 . TRP C 3 47  ? 136.763 129.879 96.340  1.00 63.13  ? 47  TRP C CE2 1 
ATOM   3785 C  CE3 . TRP C 3 47  ? 137.888 130.020 94.209  1.00 63.13  ? 47  TRP C CE3 1 
ATOM   3786 C  CZ2 . TRP C 3 47  ? 137.701 128.972 96.829  1.00 63.13  ? 47  TRP C CZ2 1 
ATOM   3787 C  CZ3 . TRP C 3 47  ? 138.817 129.120 94.696  1.00 63.13  ? 47  TRP C CZ3 1 
ATOM   3788 C  CH2 . TRP C 3 47  ? 138.718 128.606 95.993  1.00 63.13  ? 47  TRP C CH2 1 
ATOM   3789 N  N   . MET C 3 48  ? 138.250 133.595 94.564  1.00 63.15  ? 48  MET C N   1 
ATOM   3790 C  CA  . MET C 3 48  ? 139.696 133.732 94.483  1.00 63.15  ? 48  MET C CA  1 
ATOM   3791 C  C   . MET C 3 48  ? 140.439 132.663 95.266  1.00 63.15  ? 48  MET C C   1 
ATOM   3792 O  O   . MET C 3 48  ? 141.389 132.070 94.739  1.00 63.15  ? 48  MET C O   1 
ATOM   3793 C  CB  . MET C 3 48  ? 140.100 135.135 94.961  1.00 63.15  ? 48  MET C CB  1 
ATOM   3794 C  CG  . MET C 3 48  ? 141.582 135.444 94.884  1.00 63.15  ? 48  MET C CG  1 
ATOM   3795 S  SD  . MET C 3 48  ? 141.890 137.124 95.449  1.00 63.15  ? 48  MET C SD  1 
ATOM   3796 C  CE  . MET C 3 48  ? 141.600 136.927 97.202  1.00 63.15  ? 48  MET C CE  1 
ATOM   3797 N  N   . GLY C 3 49  ? 140.045 132.392 96.509  1.00 63.84  ? 49  GLY C N   1 
ATOM   3798 C  CA  . GLY C 3 49  ? 140.772 131.381 97.260  1.00 63.84  ? 49  GLY C CA  1 
ATOM   3799 C  C   . GLY C 3 49  ? 139.982 130.843 98.430  1.00 63.84  ? 49  GLY C C   1 
ATOM   3800 O  O   . GLY C 3 49  ? 138.905 131.338 98.765  1.00 63.84  ? 49  GLY C O   1 
ATOM   3801 N  N   . GLY C 3 50  ? 140.547 129.817 99.064  1.00 60.62  ? 50  GLY C N   1 
ATOM   3802 C  CA  . GLY C 3 50  ? 139.926 129.215 100.228 1.00 60.62  ? 50  GLY C CA  1 
ATOM   3803 C  C   . GLY C 3 50  ? 140.946 128.480 101.063 1.00 60.62  ? 50  GLY C C   1 
ATOM   3804 O  O   . GLY C 3 50  ? 141.945 127.971 100.544 1.00 60.62  ? 50  GLY C O   1 
ATOM   3805 N  N   . ILE C 3 51  ? 140.695 128.427 102.369 1.00 58.71  ? 51  ILE C N   1 
ATOM   3806 C  CA  . ILE C 3 51  ? 141.600 127.785 103.315 1.00 58.71  ? 51  ILE C CA  1 
ATOM   3807 C  C   . ILE C 3 51  ? 140.784 127.062 104.379 1.00 58.71  ? 51  ILE C C   1 
ATOM   3808 O  O   . ILE C 3 51  ? 139.713 127.526 104.787 1.00 58.71  ? 51  ILE C O   1 
ATOM   3809 C  CB  . ILE C 3 51  ? 142.567 128.803 103.959 1.00 58.71  ? 51  ILE C CB  1 
ATOM   3810 C  CG1 . ILE C 3 51  ? 143.645 128.083 104.769 1.00 58.71  ? 51  ILE C CG1 1 
ATOM   3811 C  CG2 . ILE C 3 51  ? 141.814 129.794 104.832 1.00 58.71  ? 51  ILE C CG2 1 
ATOM   3812 C  CD1 . ILE C 3 51  ? 144.759 128.990 105.236 1.00 58.71  ? 51  ILE C CD1 1 
ATOM   3813 N  N   . ILE C 3 52  ? 141.280 125.902 104.798 1.00 58.21  ? 52  ILE C N   1 
ATOM   3814 C  CA  . ILE C 3 52  ? 140.750 125.163 105.940 1.00 58.21  ? 52  ILE C CA  1 
ATOM   3815 C  C   . ILE C 3 52  ? 141.891 124.999 106.937 1.00 58.21  ? 52  ILE C C   1 
ATOM   3816 O  O   . ILE C 3 52  ? 142.825 124.220 106.687 1.00 58.21  ? 52  ILE C O   1 
ATOM   3817 C  CB  . ILE C 3 52  ? 140.166 123.808 105.516 1.00 58.21  ? 52  ILE C CB  1 
ATOM   3818 C  CG1 . ILE C 3 52  ? 139.341 123.956 104.238 1.00 58.21  ? 52  ILE C CG1 1 
ATOM   3819 C  CG2 . ILE C 3 52  ? 139.304 123.233 106.621 1.00 58.21  ? 52  ILE C CG2 1 
ATOM   3820 C  CD1 . ILE C 3 52  ? 138.970 122.640 103.598 1.00 58.21  ? 52  ILE C CD1 1 
ATOM   3821 N  N   . PRO C 3 53  ? 141.869 125.714 108.065 1.00 59.10  ? 53  PRO C N   1 
ATOM   3822 C  CA  . PRO C 3 53  ? 143.026 125.710 108.970 1.00 59.10  ? 53  PRO C CA  1 
ATOM   3823 C  C   . PRO C 3 53  ? 143.139 124.446 109.807 1.00 59.10  ? 53  PRO C C   1 
ATOM   3824 O  O   . PRO C 3 53  ? 144.243 124.067 110.212 1.00 59.10  ? 53  PRO C O   1 
ATOM   3825 C  CB  . PRO C 3 53  ? 142.779 126.941 109.858 1.00 59.10  ? 53  PRO C CB  1 
ATOM   3826 C  CG  . PRO C 3 53  ? 141.650 127.703 109.188 1.00 59.10  ? 53  PRO C CG  1 
ATOM   3827 C  CD  . PRO C 3 53  ? 140.834 126.650 108.522 1.00 59.10  ? 53  PRO C CD  1 
ATOM   3828 N  N   . ILE C 3 54  ? 142.009 123.792 110.081 1.00 57.51  ? 54  ILE C N   1 
ATOM   3829 C  CA  . ILE C 3 54  ? 142.034 122.591 110.913 1.00 57.51  ? 54  ILE C CA  1 
ATOM   3830 C  C   . ILE C 3 54  ? 142.814 121.477 110.223 1.00 57.51  ? 54  ILE C C   1 
ATOM   3831 O  O   . ILE C 3 54  ? 143.629 120.791 110.852 1.00 57.51  ? 54  ILE C O   1 
ATOM   3832 C  CB  . ILE C 3 54  ? 140.600 122.160 111.277 1.00 57.51  ? 54  ILE C CB  1 
ATOM   3833 C  CG1 . ILE C 3 54  ? 140.599 120.774 111.927 1.00 57.51  ? 54  ILE C CG1 1 
ATOM   3834 C  CG2 . ILE C 3 54  ? 139.684 122.226 110.068 1.00 57.51  ? 54  ILE C CG2 1 
ATOM   3835 C  CD1 . ILE C 3 54  ? 139.271 120.389 112.541 1.00 57.51  ? 54  ILE C CD1 1 
ATOM   3836 N  N   . PHE C 3 55  ? 142.588 121.282 108.924 1.00 54.51  ? 55  PHE C N   1 
ATOM   3837 C  CA  . PHE C 3 55  ? 143.417 120.376 108.140 1.00 54.51  ? 55  PHE C CA  1 
ATOM   3838 C  C   . PHE C 3 55  ? 144.555 121.085 107.420 1.00 54.51  ? 55  PHE C C   1 
ATOM   3839 O  O   . PHE C 3 55  ? 145.398 120.413 106.817 1.00 54.51  ? 55  PHE C O   1 
ATOM   3840 C  CB  . PHE C 3 55  ? 142.577 119.606 107.108 1.00 54.51  ? 55  PHE C CB  1 
ATOM   3841 C  CG  . PHE C 3 55  ? 141.471 118.776 107.704 1.00 54.51  ? 55  PHE C CG  1 
ATOM   3842 C  CD1 . PHE C 3 55  ? 140.356 119.365 108.271 1.00 54.51  ? 55  PHE C CD1 1 
ATOM   3843 C  CD2 . PHE C 3 55  ? 141.555 117.395 107.693 1.00 54.51  ? 55  PHE C CD2 1 
ATOM   3844 C  CE1 . PHE C 3 55  ? 139.346 118.595 108.815 1.00 54.51  ? 55  PHE C CE1 1 
ATOM   3845 C  CE2 . PHE C 3 55  ? 140.549 116.620 108.235 1.00 54.51  ? 55  PHE C CE2 1 
ATOM   3846 C  CZ  . PHE C 3 55  ? 139.444 117.221 108.797 1.00 54.51  ? 55  PHE C CZ  1 
ATOM   3847 N  N   . GLY C 3 56  ? 144.604 122.414 107.474 1.00 57.78  ? 56  GLY C N   1 
ATOM   3848 C  CA  . GLY C 3 56  ? 145.667 123.166 106.836 1.00 57.78  ? 56  GLY C CA  1 
ATOM   3849 C  C   . GLY C 3 56  ? 145.736 122.978 105.335 1.00 57.78  ? 56  GLY C C   1 
ATOM   3850 O  O   . GLY C 3 56  ? 146.818 122.763 104.782 1.00 57.78  ? 56  GLY C O   1 
ATOM   3851 N  N   . THR C 3 57  ? 144.590 123.055 104.662 1.00 58.74  ? 57  THR C N   1 
ATOM   3852 C  CA  . THR C 3 57  ? 144.512 122.852 103.221 1.00 58.74  ? 57  THR C CA  1 
ATOM   3853 C  C   . THR C 3 57  ? 144.142 124.163 102.544 1.00 58.74  ? 57  THR C C   1 
ATOM   3854 O  O   . THR C 3 57  ? 143.150 124.798 102.914 1.00 58.74  ? 57  THR C O   1 
ATOM   3855 C  CB  . THR C 3 57  ? 143.487 121.770 102.871 1.00 58.74  ? 57  THR C CB  1 
ATOM   3856 O  OG1 . THR C 3 57  ? 143.737 120.600 103.659 1.00 58.74  ? 57  THR C OG1 1 
ATOM   3857 C  CG2 . THR C 3 57  ? 143.576 121.410 101.396 1.00 58.74  ? 57  THR C CG2 1 
ATOM   3858 N  N   . ALA C 3 58  ? 144.929 124.558 101.546 1.00 59.75  ? 58  ALA C N   1 
ATOM   3859 C  CA  . ALA C 3 58  ? 144.728 125.811 100.828 1.00 59.75  ? 58  ALA C CA  1 
ATOM   3860 C  C   . ALA C 3 58  ? 144.431 125.505 99.367  1.00 59.75  ? 58  ALA C C   1 
ATOM   3861 O  O   . ALA C 3 58  ? 145.182 124.767 98.720  1.00 59.75  ? 58  ALA C O   1 
ATOM   3862 C  CB  . ALA C 3 58  ? 145.954 126.717 100.950 1.00 59.75  ? 58  ALA C CB  1 
ATOM   3863 N  N   . ASN C 3 59  ? 143.343 126.072 98.851  1.00 61.44  ? 59  ASN C N   1 
ATOM   3864 C  CA  . ASN C 3 59  ? 142.944 125.901 97.463  1.00 61.44  ? 59  ASN C CA  1 
ATOM   3865 C  C   . ASN C 3 59  ? 142.805 127.264 96.797  1.00 61.44  ? 59  ASN C C   1 
ATOM   3866 O  O   . ASN C 3 59  ? 142.331 128.228 97.406  1.00 61.44  ? 59  ASN C O   1 
ATOM   3867 C  CB  . ASN C 3 59  ? 141.624 125.131 97.355  1.00 61.44  ? 59  ASN C CB  1 
ATOM   3868 C  CG  . ASN C 3 59  ? 141.764 123.678 97.760  1.00 61.44  ? 59  ASN C CG  1 
ATOM   3869 O  OD1 . ASN C 3 59  ? 142.470 122.906 97.111  1.00 61.44  ? 59  ASN C OD1 1 
ATOM   3870 N  ND2 . ASN C 3 59  ? 141.092 123.298 98.840  1.00 61.44  ? 59  ASN C ND2 1 
ATOM   3871 N  N   . TYR C 3 60  ? 143.229 127.337 95.537  1.00 60.28  ? 60  TYR C N   1 
ATOM   3872 C  CA  . TYR C 3 60  ? 143.181 128.578 94.779  1.00 60.28  ? 60  TYR C CA  1 
ATOM   3873 C  C   . TYR C 3 60  ? 142.475 128.334 93.454  1.00 60.28  ? 60  TYR C C   1 
ATOM   3874 O  O   . TYR C 3 60  ? 142.410 127.207 92.957  1.00 60.28  ? 60  TYR C O   1 
ATOM   3875 C  CB  . TYR C 3 60  ? 144.582 129.153 94.525  1.00 60.28  ? 60  TYR C CB  1 
ATOM   3876 C  CG  . TYR C 3 60  ? 145.478 129.188 95.741  1.00 60.28  ? 60  TYR C CG  1 
ATOM   3877 C  CD1 . TYR C 3 60  ? 145.040 129.736 96.937  1.00 60.28  ? 60  TYR C CD1 1 
ATOM   3878 C  CD2 . TYR C 3 60  ? 146.770 128.686 95.688  1.00 60.28  ? 60  TYR C CD2 1 
ATOM   3879 C  CE1 . TYR C 3 60  ? 145.857 129.772 98.047  1.00 60.28  ? 60  TYR C CE1 1 
ATOM   3880 C  CE2 . TYR C 3 60  ? 147.595 128.719 96.793  1.00 60.28  ? 60  TYR C CE2 1 
ATOM   3881 C  CZ  . TYR C 3 60  ? 147.134 129.263 97.970  1.00 60.28  ? 60  TYR C CZ  1 
ATOM   3882 O  OH  . TYR C 3 60  ? 147.953 129.298 99.074  1.00 60.28  ? 60  TYR C OH  1 
ATOM   3883 N  N   . ALA C 3 61  ? 141.943 129.412 92.887  1.00 62.99  ? 61  ALA C N   1 
ATOM   3884 C  CA  . ALA C 3 61  ? 141.289 129.346 91.592  1.00 62.99  ? 61  ALA C CA  1 
ATOM   3885 C  C   . ALA C 3 61  ? 142.317 129.125 90.487  1.00 62.99  ? 61  ALA C C   1 
ATOM   3886 O  O   . ALA C 3 61  ? 143.521 129.323 90.672  1.00 62.99  ? 61  ALA C O   1 
ATOM   3887 C  CB  . ALA C 3 61  ? 140.493 130.623 91.322  1.00 62.99  ? 61  ALA C CB  1 
ATOM   3888 N  N   . GLN C 3 62  ? 141.821 128.701 89.322  1.00 66.20  ? 62  GLN C N   1 
ATOM   3889 C  CA  . GLN C 3 62  ? 142.709 128.398 88.204  1.00 66.20  ? 62  GLN C CA  1 
ATOM   3890 C  C   . GLN C 3 62  ? 143.468 129.635 87.742  1.00 66.20  ? 62  GLN C C   1 
ATOM   3891 O  O   . GLN C 3 62  ? 144.669 129.565 87.454  1.00 66.20  ? 62  GLN C O   1 
ATOM   3892 C  CB  . GLN C 3 62  ? 141.907 127.801 87.047  1.00 66.20  ? 62  GLN C CB  1 
ATOM   3893 C  CG  . GLN C 3 62  ? 141.319 126.431 87.337  1.00 66.20  ? 62  GLN C CG  1 
ATOM   3894 C  CD  . GLN C 3 62  ? 140.576 125.854 86.148  1.00 66.20  ? 62  GLN C CD  1 
ATOM   3895 O  OE1 . GLN C 3 62  ? 140.079 126.589 85.295  1.00 66.20  ? 62  GLN C OE1 1 
ATOM   3896 N  NE2 . GLN C 3 62  ? 140.497 124.530 86.085  1.00 66.20  ? 62  GLN C NE2 1 
ATOM   3897 N  N   . LYS C 3 63  ? 142.784 130.778 87.660  1.00 68.12  ? 63  LYS C N   1 
ATOM   3898 C  CA  . LYS C 3 63  ? 143.421 131.993 87.161  1.00 68.12  ? 63  LYS C CA  1 
ATOM   3899 C  C   . LYS C 3 63  ? 144.497 132.497 88.115  1.00 68.12  ? 63  LYS C C   1 
ATOM   3900 O  O   . LYS C 3 63  ? 145.552 132.968 87.675  1.00 68.12  ? 63  LYS C O   1 
ATOM   3901 C  CB  . LYS C 3 63  ? 142.370 133.076 86.924  1.00 68.12  ? 63  LYS C CB  1 
ATOM   3902 C  CG  . LYS C 3 63  ? 141.304 132.704 85.908  1.00 68.12  ? 63  LYS C CG  1 
ATOM   3903 C  CD  . LYS C 3 63  ? 140.255 133.798 85.788  1.00 68.12  ? 63  LYS C CD  1 
ATOM   3904 C  CE  . LYS C 3 63  ? 139.189 133.435 84.769  1.00 68.12  ? 63  LYS C CE  1 
ATOM   3905 N  NZ  . LYS C 3 63  ? 138.138 134.486 84.670  1.00 68.12  ? 63  LYS C NZ  1 
ATOM   3906 N  N   . PHE C 3 64  ? 144.253 132.407 89.421  1.00 66.95  ? 64  PHE C N   1 
ATOM   3907 C  CA  . PHE C 3 64  ? 145.104 133.037 90.421  1.00 66.95  ? 64  PHE C CA  1 
ATOM   3908 C  C   . PHE C 3 64  ? 146.143 132.091 91.010  1.00 66.95  ? 64  PHE C C   1 
ATOM   3909 O  O   . PHE C 3 64  ? 146.801 132.451 91.992  1.00 66.95  ? 64  PHE C O   1 
ATOM   3910 C  CB  . PHE C 3 64  ? 144.246 133.627 91.542  1.00 66.95  ? 64  PHE C CB  1 
ATOM   3911 C  CG  . PHE C 3 64  ? 143.267 134.664 91.073  1.00 66.95  ? 64  PHE C CG  1 
ATOM   3912 C  CD1 . PHE C 3 64  ? 143.685 135.955 90.795  1.00 66.95  ? 64  PHE C CD1 1 
ATOM   3913 C  CD2 . PHE C 3 64  ? 141.928 134.349 90.913  1.00 66.95  ? 64  PHE C CD2 1 
ATOM   3914 C  CE1 . PHE C 3 64  ? 142.786 136.912 90.364  1.00 66.95  ? 64  PHE C CE1 1 
ATOM   3915 C  CE2 . PHE C 3 64  ? 141.024 135.301 90.483  1.00 66.95  ? 64  PHE C CE2 1 
ATOM   3916 C  CZ  . PHE C 3 64  ? 141.453 136.584 90.208  1.00 66.95  ? 64  PHE C CZ  1 
ATOM   3917 N  N   . GLN C 3 65  ? 146.302 130.895 90.448  1.00 69.50  ? 65  GLN C N   1 
ATOM   3918 C  CA  . GLN C 3 65  ? 147.314 129.971 90.944  1.00 69.50  ? 65  GLN C CA  1 
ATOM   3919 C  C   . GLN C 3 65  ? 148.706 130.565 90.773  1.00 69.50  ? 65  GLN C C   1 
ATOM   3920 O  O   . GLN C 3 65  ? 149.052 131.073 89.703  1.00 69.50  ? 65  GLN C O   1 
ATOM   3921 C  CB  . GLN C 3 65  ? 147.218 128.632 90.214  1.00 69.50  ? 65  GLN C CB  1 
ATOM   3922 C  CG  . GLN C 3 65  ? 146.275 127.635 90.866  1.00 69.50  ? 65  GLN C CG  1 
ATOM   3923 C  CD  . GLN C 3 65  ? 146.254 126.298 90.151  1.00 69.50  ? 65  GLN C CD  1 
ATOM   3924 O  OE1 . GLN C 3 65  ? 146.884 126.130 89.107  1.00 69.50  ? 65  GLN C OE1 1 
ATOM   3925 N  NE2 . GLN C 3 65  ? 145.527 125.338 90.712  1.00 69.50  ? 65  GLN C NE2 1 
ATOM   3926 N  N   . GLY C 3 66  ? 149.504 130.498 91.834  1.00 71.21  ? 66  GLY C N   1 
ATOM   3927 C  CA  . GLY C 3 66  ? 150.846 131.039 91.805  1.00 71.21  ? 66  GLY C CA  1 
ATOM   3928 C  C   . GLY C 3 66  ? 150.955 132.521 92.081  1.00 71.21  ? 66  GLY C C   1 
ATOM   3929 O  O   . GLY C 3 66  ? 152.065 133.062 92.027  1.00 71.21  ? 66  GLY C O   1 
ATOM   3930 N  N   . ARG C 3 67  ? 149.851 133.194 92.372  1.00 70.26  ? 67  ARG C N   1 
ATOM   3931 C  CA  . ARG C 3 67  ? 149.898 134.617 92.690  1.00 70.26  ? 67  ARG C CA  1 
ATOM   3932 C  C   . ARG C 3 67  ? 149.238 134.955 94.018  1.00 70.26  ? 67  ARG C C   1 
ATOM   3933 O  O   . ARG C 3 67  ? 149.680 135.887 94.694  1.00 70.26  ? 67  ARG C O   1 
ATOM   3934 C  CB  . ARG C 3 67  ? 149.243 135.437 91.567  1.00 70.26  ? 67  ARG C CB  1 
ATOM   3935 C  CG  . ARG C 3 67  ? 150.133 135.647 90.353  1.00 70.26  ? 67  ARG C CG  1 
ATOM   3936 C  CD  . ARG C 3 67  ? 149.480 136.579 89.347  1.00 70.26  ? 67  ARG C CD  1 
ATOM   3937 N  NE  . ARG C 3 67  ? 149.039 137.822 89.968  1.00 70.26  ? 67  ARG C NE  1 
ATOM   3938 C  CZ  . ARG C 3 67  ? 147.876 138.409 89.727  1.00 70.26  ? 67  ARG C CZ  1 
ATOM   3939 N  NH1 . ARG C 3 67  ? 147.004 137.893 88.877  1.00 70.26  ? 67  ARG C NH1 1 
ATOM   3940 N  NH2 . ARG C 3 67  ? 147.579 139.544 90.354  1.00 70.26  ? 67  ARG C NH2 1 
ATOM   3941 N  N   . VAL C 3 68  ? 148.197 134.226 94.409  1.00 65.32  ? 68  VAL C N   1 
ATOM   3942 C  CA  . VAL C 3 68  ? 147.470 134.480 95.648  1.00 65.32  ? 68  VAL C CA  1 
ATOM   3943 C  C   . VAL C 3 68  ? 147.907 133.454 96.684  1.00 65.32  ? 68  VAL C C   1 
ATOM   3944 O  O   . VAL C 3 68  ? 148.042 132.264 96.375  1.00 65.32  ? 68  VAL C O   1 
ATOM   3945 C  CB  . VAL C 3 68  ? 145.946 134.448 95.428  1.00 65.32  ? 68  VAL C CB  1 
ATOM   3946 C  CG1 . VAL C 3 68  ? 145.491 133.087 94.923  1.00 65.32  ? 68  VAL C CG1 1 
ATOM   3947 C  CG2 . VAL C 3 68  ? 145.214 134.818 96.710  1.00 65.32  ? 68  VAL C CG2 1 
ATOM   3948 N  N   . THR C 3 69  ? 148.162 133.923 97.903  1.00 64.31  ? 69  THR C N   1 
ATOM   3949 C  CA  . THR C 3 69  ? 148.558 133.059 99.008  1.00 64.31  ? 69  THR C CA  1 
ATOM   3950 C  C   . THR C 3 69  ? 147.662 133.344 100.203 1.00 64.31  ? 69  THR C C   1 
ATOM   3951 O  O   . THR C 3 69  ? 147.490 134.503 100.591 1.00 64.31  ? 69  THR C O   1 
ATOM   3952 C  CB  . THR C 3 69  ? 150.027 133.276 99.386  1.00 64.31  ? 69  THR C CB  1 
ATOM   3953 O  OG1 . THR C 3 69  ? 150.851 133.115 98.225  1.00 64.31  ? 69  THR C OG1 1 
ATOM   3954 C  CG2 . THR C 3 69  ? 150.457 132.276 100.449 1.00 64.31  ? 69  THR C CG2 1 
ATOM   3955 N  N   . ILE C 3 70  ? 147.097 132.292 100.786 1.00 62.82  ? 70  ILE C N   1 
ATOM   3956 C  CA  . ILE C 3 70  ? 146.224 132.415 101.947 1.00 62.82  ? 70  ILE C CA  1 
ATOM   3957 C  C   . ILE C 3 70  ? 146.843 131.627 103.092 1.00 62.82  ? 70  ILE C C   1 
ATOM   3958 O  O   . ILE C 3 70  ? 147.158 130.441 102.938 1.00 62.82  ? 70  ILE C O   1 
ATOM   3959 C  CB  . ILE C 3 70  ? 144.800 131.924 101.650 1.00 62.82  ? 70  ILE C CB  1 
ATOM   3960 C  CG1 . ILE C 3 70  ? 144.186 132.735 100.509 1.00 62.82  ? 70  ILE C CG1 1 
ATOM   3961 C  CG2 . ILE C 3 70  ? 143.936 132.038 102.888 1.00 62.82  ? 70  ILE C CG2 1 
ATOM   3962 C  CD1 . ILE C 3 70  ? 142.801 132.279 100.119 1.00 62.82  ? 70  ILE C CD1 1 
ATOM   3963 N  N   . THR C 3 71  ? 147.014 132.286 104.234 1.00 66.99  ? 71  THR C N   1 
ATOM   3964 C  CA  . THR C 3 71  ? 147.571 131.672 105.428 1.00 66.99  ? 71  THR C CA  1 
ATOM   3965 C  C   . THR C 3 71  ? 146.652 131.935 106.613 1.00 66.99  ? 71  THR C C   1 
ATOM   3966 O  O   . THR C 3 71  ? 145.858 132.878 106.612 1.00 66.99  ? 71  THR C O   1 
ATOM   3967 C  CB  . THR C 3 71  ? 148.979 132.203 105.732 1.00 66.99  ? 71  THR C CB  1 
ATOM   3968 O  OG1 . THR C 3 71  ? 148.931 133.627 105.890 1.00 66.99  ? 71  THR C OG1 1 
ATOM   3969 C  CG2 . THR C 3 71  ? 149.940 131.854 104.605 1.00 66.99  ? 71  THR C CG2 1 
ATOM   3970 N  N   . ALA C 3 72  ? 146.763 131.085 107.630 1.00 70.22  ? 72  ALA C N   1 
ATOM   3971 C  CA  . ALA C 3 72  ? 145.943 131.197 108.826 1.00 70.22  ? 72  ALA C CA  1 
ATOM   3972 C  C   . ALA C 3 72  ? 146.830 131.230 110.060 1.00 70.22  ? 72  ALA C C   1 
ATOM   3973 O  O   . ALA C 3 72  ? 147.848 130.533 110.123 1.00 70.22  ? 72  ALA C O   1 
ATOM   3974 C  CB  . ALA C 3 72  ? 144.946 130.037 108.930 1.00 70.22  ? 72  ALA C CB  1 
ATOM   3975 N  N   . ASP C 3 73  ? 146.440 132.044 111.036 1.00 73.70  ? 73  ASP C N   1 
ATOM   3976 C  CA  . ASP C 3 73  ? 147.129 132.152 112.319 1.00 73.70  ? 73  ASP C CA  1 
ATOM   3977 C  C   . ASP C 3 73  ? 146.087 131.916 113.408 1.00 73.70  ? 73  ASP C C   1 
ATOM   3978 O  O   . ASP C 3 73  ? 145.290 132.808 113.719 1.00 73.70  ? 73  ASP C O   1 
ATOM   3979 C  CB  . ASP C 3 73  ? 147.805 133.512 112.468 1.00 73.70  ? 73  ASP C CB  1 
ATOM   3980 C  CG  . ASP C 3 73  ? 148.743 133.569 113.656 1.00 73.70  ? 73  ASP C CG  1 
ATOM   3981 O  OD1 . ASP C 3 73  ? 149.096 132.497 114.190 1.00 73.70  ? 73  ASP C OD1 1 
ATOM   3982 O  OD2 . ASP C 3 73  ? 149.129 134.688 114.055 1.00 73.70  ? 73  ASP C OD2 1 
ATOM   3983 N  N   . GLU C 3 74  ? 146.088 130.709 113.977 1.00 75.14  ? 74  GLU C N   1 
ATOM   3984 C  CA  . GLU C 3 74  ? 145.100 130.359 114.989 1.00 75.14  ? 74  GLU C CA  1 
ATOM   3985 C  C   . GLU C 3 74  ? 145.392 131.006 116.335 1.00 75.14  ? 74  GLU C C   1 
ATOM   3986 O  O   . GLU C 3 74  ? 144.527 130.984 117.218 1.00 75.14  ? 74  GLU C O   1 
ATOM   3987 C  CB  . GLU C 3 74  ? 145.023 128.840 115.144 1.00 75.14  ? 74  GLU C CB  1 
ATOM   3988 C  CG  . GLU C 3 74  ? 144.378 128.133 113.963 1.00 75.14  ? 74  GLU C CG  1 
ATOM   3989 C  CD  . GLU C 3 74  ? 144.135 126.660 114.225 1.00 75.14  ? 74  GLU C CD  1 
ATOM   3990 O  OE1 . GLU C 3 74  ? 143.475 126.336 115.235 1.00 75.14  ? 74  GLU C OE1 1 
ATOM   3991 O  OE2 . GLU C 3 74  ? 144.604 125.827 113.421 1.00 75.14  ? 74  GLU C OE2 1 
ATOM   3992 N  N   . SER C 3 75  ? 146.588 131.571 116.518 1.00 74.36  ? 75  SER C N   1 
ATOM   3993 C  CA  . SER C 3 75  ? 146.881 132.288 117.754 1.00 74.36  ? 75  SER C CA  1 
ATOM   3994 C  C   . SER C 3 75  ? 145.966 133.494 117.917 1.00 74.36  ? 75  SER C C   1 
ATOM   3995 O  O   . SER C 3 75  ? 145.453 133.753 119.012 1.00 74.36  ? 75  SER C O   1 
ATOM   3996 C  CB  . SER C 3 75  ? 148.347 132.718 117.776 1.00 74.36  ? 75  SER C CB  1 
ATOM   3997 O  OG  . SER C 3 75  ? 148.587 133.756 116.841 1.00 74.36  ? 75  SER C OG  1 
ATOM   3998 N  N   . THR C 3 76  ? 145.748 134.242 116.837 1.00 72.16  ? 76  THR C N   1 
ATOM   3999 C  CA  . THR C 3 76  ? 144.821 135.363 116.832 1.00 72.16  ? 76  THR C CA  1 
ATOM   4000 C  C   . THR C 3 76  ? 143.612 135.123 115.940 1.00 72.16  ? 76  THR C C   1 
ATOM   4001 O  O   . THR C 3 76  ? 142.799 136.038 115.766 1.00 72.16  ? 76  THR C O   1 
ATOM   4002 C  CB  . THR C 3 76  ? 145.538 136.644 116.390 1.00 72.16  ? 76  THR C CB  1 
ATOM   4003 O  OG1 . THR C 3 76  ? 145.885 136.546 115.003 1.00 72.16  ? 76  THR C OG1 1 
ATOM   4004 C  CG2 . THR C 3 76  ? 146.803 136.857 117.209 1.00 72.16  ? 76  THR C CG2 1 
ATOM   4005 N  N   . SER C 3 77  ? 143.471 133.921 115.379 1.00 69.60  ? 77  SER C N   1 
ATOM   4006 C  CA  . SER C 3 77  ? 142.371 133.577 114.476 1.00 69.60  ? 77  SER C CA  1 
ATOM   4007 C  C   . SER C 3 77  ? 142.289 134.561 113.313 1.00 69.60  ? 77  SER C C   1 
ATOM   4008 O  O   . SER C 3 77  ? 141.225 135.086 112.978 1.00 69.60  ? 77  SER C O   1 
ATOM   4009 C  CB  . SER C 3 77  ? 141.041 133.505 115.228 1.00 69.60  ? 77  SER C CB  1 
ATOM   4010 O  OG  . SER C 3 77  ? 140.628 134.789 115.660 1.00 69.60  ? 77  SER C OG  1 
ATOM   4011 N  N   . THR C 3 78  ? 143.437 134.813 112.691 1.00 70.15  ? 78  THR C N   1 
ATOM   4012 C  CA  . THR C 3 78  ? 143.555 135.796 111.623 1.00 70.15  ? 78  THR C CA  1 
ATOM   4013 C  C   . THR C 3 78  ? 143.919 135.106 110.316 1.00 70.15  ? 78  THR C C   1 
ATOM   4014 O  O   . THR C 3 78  ? 144.893 134.349 110.258 1.00 70.15  ? 78  THR C O   1 
ATOM   4015 C  CB  . THR C 3 78  ? 144.606 136.852 111.969 1.00 70.15  ? 78  THR C CB  1 
ATOM   4016 O  OG1 . THR C 3 78  ? 144.196 137.572 113.139 1.00 70.15  ? 78  THR C OG1 1 
ATOM   4017 C  CG2 . THR C 3 78  ? 144.778 137.823 110.820 1.00 70.15  ? 78  THR C CG2 1 
ATOM   4018 N  N   . ALA C 3 79  ? 143.140 135.372 109.273 1.00 65.92  ? 79  ALA C N   1 
ATOM   4019 C  CA  . ALA C 3 79  ? 143.416 134.870 107.935 1.00 65.92  ? 79  ALA C CA  1 
ATOM   4020 C  C   . ALA C 3 79  ? 144.080 135.977 107.127 1.00 65.92  ? 79  ALA C C   1 
ATOM   4021 O  O   . ALA C 3 79  ? 143.513 137.065 106.975 1.00 65.92  ? 79  ALA C O   1 
ATOM   4022 C  CB  . ALA C 3 79  ? 142.134 134.395 107.253 1.00 65.92  ? 79  ALA C CB  1 
ATOM   4023 N  N   . TYR C 3 80  ? 145.279 135.701 106.624 1.00 67.41  ? 80  TYR C N   1 
ATOM   4024 C  CA  . TYR C 3 80  ? 146.033 136.642 105.807 1.00 67.41  ? 80  TYR C CA  1 
ATOM   4025 C  C   . TYR C 3 80  ? 145.938 136.230 104.345 1.00 67.41  ? 80  TYR C C   1 
ATOM   4026 O  O   . TYR C 3 80  ? 146.158 135.061 104.007 1.00 67.41  ? 80  TYR C O   1 
ATOM   4027 C  CB  . TYR C 3 80  ? 147.499 136.698 106.239 1.00 67.41  ? 80  TYR C CB  1 
ATOM   4028 C  CG  . TYR C 3 80  ? 147.721 137.189 107.651 1.00 67.41  ? 80  TYR C CG  1 
ATOM   4029 C  CD1 . TYR C 3 80  ? 147.796 138.546 107.931 1.00 67.41  ? 80  TYR C CD1 1 
ATOM   4030 C  CD2 . TYR C 3 80  ? 147.872 136.294 108.701 1.00 67.41  ? 80  TYR C CD2 1 
ATOM   4031 C  CE1 . TYR C 3 80  ? 148.005 138.999 109.218 1.00 67.41  ? 80  TYR C CE1 1 
ATOM   4032 C  CE2 . TYR C 3 80  ? 148.082 136.737 109.992 1.00 67.41  ? 80  TYR C CE2 1 
ATOM   4033 C  CZ  . TYR C 3 80  ? 148.149 138.091 110.245 1.00 67.41  ? 80  TYR C CZ  1 
ATOM   4034 O  OH  . TYR C 3 80  ? 148.356 138.538 111.530 1.00 67.41  ? 80  TYR C OH  1 
ATOM   4035 N  N   . MET C 3 81  ? 145.610 137.189 103.487 1.00 67.57  ? 81  MET C N   1 
ATOM   4036 C  CA  . MET C 3 81  ? 145.487 136.971 102.053 1.00 67.57  ? 81  MET C CA  1 
ATOM   4037 C  C   . MET C 3 81  ? 146.430 137.924 101.331 1.00 67.57  ? 81  MET C C   1 
ATOM   4038 O  O   . MET C 3 81  ? 146.369 139.137 101.545 1.00 67.57  ? 81  MET C O   1 
ATOM   4039 C  CB  . MET C 3 81  ? 144.036 137.180 101.616 1.00 67.57  ? 81  MET C CB  1 
ATOM   4040 C  CG  . MET C 3 81  ? 143.741 136.927 100.155 1.00 67.57  ? 81  MET C CG  1 
ATOM   4041 S  SD  . MET C 3 81  ? 144.164 138.341 99.129  1.00 67.57  ? 81  MET C SD  1 
ATOM   4042 C  CE  . MET C 3 81  ? 142.870 139.497 99.570  1.00 67.57  ? 81  MET C CE  1 
ATOM   4043 N  N   . GLU C 3 82  ? 147.290 137.383 100.470 1.00 68.97  ? 82  GLU C N   1 
ATOM   4044 C  CA  . GLU C 3 82  ? 148.379 138.149 99.881  1.00 68.97  ? 82  GLU C CA  1 
ATOM   4045 C  C   . GLU C 3 82  ? 148.418 137.964 98.370  1.00 68.97  ? 82  GLU C C   1 
ATOM   4046 O  O   . GLU C 3 82  ? 148.329 136.835 97.874  1.00 68.97  ? 82  GLU C O   1 
ATOM   4047 C  CB  . GLU C 3 82  ? 149.720 137.736 100.495 1.00 68.97  ? 82  GLU C CB  1 
ATOM   4048 C  CG  . GLU C 3 82  ? 150.930 138.018 99.619  1.00 68.97  ? 82  GLU C CG  1 
ATOM   4049 C  CD  . GLU C 3 82  ? 152.208 137.431 100.184 1.00 68.97  ? 82  GLU C CD  1 
ATOM   4050 O  OE1 . GLU C 3 82  ? 152.409 137.511 101.414 1.00 68.97  ? 82  GLU C OE1 1 
ATOM   4051 O  OE2 . GLU C 3 82  ? 153.014 136.889 99.398  1.00 68.97  ? 82  GLU C OE2 1 
ATOM   4052 N  N   . LEU C 3 83  ? 148.552 139.076 97.651  1.00 72.77  ? 83  LEU C N   1 
ATOM   4053 C  CA  . LEU C 3 83  ? 148.851 139.081 96.224  1.00 72.77  ? 83  LEU C CA  1 
ATOM   4054 C  C   . LEU C 3 83  ? 150.254 139.623 96.000  1.00 72.77  ? 83  LEU C C   1 
ATOM   4055 O  O   . LEU C 3 83  ? 150.699 140.526 96.718  1.00 72.77  ? 83  LEU C O   1 
ATOM   4056 C  CB  . LEU C 3 83  ? 147.857 139.928 95.422  1.00 72.77  ? 83  LEU C CB  1 
ATOM   4057 C  CG  . LEU C 3 83  ? 146.461 139.419 95.065  1.00 72.77  ? 83  LEU C CG  1 
ATOM   4058 C  CD1 . LEU C 3 83  ? 145.570 139.394 96.273  1.00 72.77  ? 83  LEU C CD1 1 
ATOM   4059 C  CD2 . LEU C 3 83  ? 145.849 140.275 93.967  1.00 72.77  ? 83  LEU C CD2 1 
ATOM   4060 N  N   . SER C 3 84  ? 150.936 139.081 94.997  1.00 76.66  ? 84  SER C N   1 
ATOM   4061 C  CA  . SER C 3 84  ? 152.237 139.559 94.560  1.00 76.66  ? 84  SER C CA  1 
ATOM   4062 C  C   . SER C 3 84  ? 152.166 139.977 93.097  1.00 76.66  ? 84  SER C C   1 
ATOM   4063 O  O   . SER C 3 84  ? 151.330 139.490 92.330  1.00 76.66  ? 84  SER C O   1 
ATOM   4064 C  CB  . SER C 3 84  ? 153.312 138.482 94.751  1.00 76.66  ? 84  SER C CB  1 
ATOM   4065 O  OG  . SER C 3 84  ? 153.107 137.395 93.865  1.00 76.66  ? 84  SER C OG  1 
ATOM   4066 N  N   . SER C 3 85  ? 153.059 140.894 92.721  1.00 81.41  ? 85  SER C N   1 
ATOM   4067 C  CA  . SER C 3 85  ? 153.110 141.457 91.370  1.00 81.41  ? 85  SER C CA  1 
ATOM   4068 C  C   . SER C 3 85  ? 151.772 142.102 91.000  1.00 81.41  ? 85  SER C C   1 
ATOM   4069 O  O   . SER C 3 85  ? 151.076 141.681 90.074  1.00 81.41  ? 85  SER C O   1 
ATOM   4070 C  CB  . SER C 3 85  ? 153.518 140.393 90.345  1.00 81.41  ? 85  SER C CB  1 
ATOM   4071 O  OG  . SER C 3 85  ? 154.746 139.784 90.703  1.00 81.41  ? 85  SER C OG  1 
ATOM   4072 N  N   . LEU C 3 86  ? 151.422 143.141 91.757  1.00 82.51  ? 86  LEU C N   1 
ATOM   4073 C  CA  . LEU C 3 86  ? 150.154 143.830 91.559  1.00 82.51  ? 86  LEU C CA  1 
ATOM   4074 C  C   . LEU C 3 86  ? 150.135 144.546 90.214  1.00 82.51  ? 86  LEU C C   1 
ATOM   4075 O  O   . LEU C 3 86  ? 151.128 145.157 89.808  1.00 82.51  ? 86  LEU C O   1 
ATOM   4076 C  CB  . LEU C 3 86  ? 149.917 144.830 92.689  1.00 82.51  ? 86  LEU C CB  1 
ATOM   4077 C  CG  . LEU C 3 86  ? 149.306 144.283 93.980  1.00 82.51  ? 86  LEU C CG  1 
ATOM   4078 C  CD1 . LEU C 3 86  ? 149.379 145.325 95.085  1.00 82.51  ? 86  LEU C CD1 1 
ATOM   4079 C  CD2 . LEU C 3 86  ? 147.873 143.837 93.753  1.00 82.51  ? 86  LEU C CD2 1 
ATOM   4080 N  N   . ARG C 3 87  ? 149.002 144.471 89.526  1.00 84.29  ? 87  ARG C N   1 
ATOM   4081 C  CA  . ARG C 3 87  ? 148.792 145.140 88.250  1.00 84.29  ? 87  ARG C CA  1 
ATOM   4082 C  C   . ARG C 3 87  ? 147.696 146.191 88.399  1.00 84.29  ? 87  ARG C C   1 
ATOM   4083 O  O   . ARG C 3 87  ? 147.000 146.259 89.415  1.00 84.29  ? 87  ARG C O   1 
ATOM   4084 C  CB  . ARG C 3 87  ? 148.442 144.130 87.154  1.00 84.29  ? 87  ARG C CB  1 
ATOM   4085 C  CG  . ARG C 3 87  ? 149.362 142.921 87.109  1.00 84.29  ? 87  ARG C CG  1 
ATOM   4086 C  CD  . ARG C 3 87  ? 148.925 141.934 86.040  1.00 84.29  ? 87  ARG C CD  1 
ATOM   4087 N  NE  . ARG C 3 87  ? 149.811 140.777 85.971  1.00 84.29  ? 87  ARG C NE  1 
ATOM   4088 C  CZ  . ARG C 3 87  ? 149.598 139.716 85.205  1.00 84.29  ? 87  ARG C CZ  1 
ATOM   4089 N  NH1 . ARG C 3 87  ? 148.533 139.629 84.425  1.00 84.29  ? 87  ARG C NH1 1 
ATOM   4090 N  NH2 . ARG C 3 87  ? 150.476 138.718 85.221  1.00 84.29  ? 87  ARG C NH2 1 
ATOM   4091 N  N   . SER C 3 88  ? 147.547 147.020 87.362  1.00 83.61  ? 88  SER C N   1 
ATOM   4092 C  CA  . SER C 3 88  ? 146.560 148.093 87.396  1.00 83.61  ? 88  SER C CA  1 
ATOM   4093 C  C   . SER C 3 88  ? 145.129 147.571 87.422  1.00 83.61  ? 88  SER C C   1 
ATOM   4094 O  O   . SER C 3 88  ? 144.223 148.305 87.829  1.00 83.61  ? 88  SER C O   1 
ATOM   4095 C  CB  . SER C 3 88  ? 146.750 149.021 86.196  1.00 83.61  ? 88  SER C CB  1 
ATOM   4096 O  OG  . SER C 3 88  ? 148.034 149.621 86.214  1.00 83.61  ? 88  SER C OG  1 
ATOM   4097 N  N   . GLU C 3 89  ? 144.906 146.329 87.000  1.00 82.94  ? 89  GLU C N   1 
ATOM   4098 C  CA  . GLU C 3 89  ? 143.579 145.729 87.003  1.00 82.94  ? 89  GLU C CA  1 
ATOM   4099 C  C   . GLU C 3 89  ? 143.232 145.079 88.334  1.00 82.94  ? 89  GLU C C   1 
ATOM   4100 O  O   . GLU C 3 89  ? 142.172 144.453 88.446  1.00 82.94  ? 89  GLU C O   1 
ATOM   4101 C  CB  . GLU C 3 89  ? 143.461 144.700 85.876  1.00 82.94  ? 89  GLU C CB  1 
ATOM   4102 C  CG  . GLU C 3 89  ? 143.533 145.294 84.480  1.00 82.94  ? 89  GLU C CG  1 
ATOM   4103 C  CD  . GLU C 3 89  ? 144.952 145.382 83.955  1.00 82.94  ? 89  GLU C CD  1 
ATOM   4104 O  OE1 . GLU C 3 89  ? 145.876 144.916 84.654  1.00 82.94  ? 89  GLU C OE1 1 
ATOM   4105 O  OE2 . GLU C 3 89  ? 145.143 145.917 82.843  1.00 82.94  ? 89  GLU C OE2 1 
ATOM   4106 N  N   . ASP C 3 90  ? 144.094 145.209 89.339  1.00 78.97  ? 90  ASP C N   1 
ATOM   4107 C  CA  . ASP C 3 90  ? 143.857 144.619 90.648  1.00 78.97  ? 90  ASP C CA  1 
ATOM   4108 C  C   . ASP C 3 90  ? 142.995 145.492 91.548  1.00 78.97  ? 90  ASP C C   1 
ATOM   4109 O  O   . ASP C 3 90  ? 142.738 145.109 92.694  1.00 78.97  ? 90  ASP C O   1 
ATOM   4110 C  CB  . ASP C 3 90  ? 145.188 144.323 91.345  1.00 78.97  ? 90  ASP C CB  1 
ATOM   4111 C  CG  . ASP C 3 90  ? 145.898 143.119 90.759  1.00 78.97  ? 90  ASP C CG  1 
ATOM   4112 O  OD1 . ASP C 3 90  ? 145.280 142.035 90.697  1.00 78.97  ? 90  ASP C OD1 1 
ATOM   4113 O  OD2 . ASP C 3 90  ? 147.074 143.254 90.364  1.00 78.97  ? 90  ASP C OD2 1 
ATOM   4114 N  N   . THR C 3 91  ? 142.544 146.649 91.068  1.00 73.76  ? 91  THR C N   1 
ATOM   4115 C  CA  . THR C 3 91  ? 141.656 147.490 91.859  1.00 73.76  ? 91  THR C CA  1 
ATOM   4116 C  C   . THR C 3 91  ? 140.260 146.873 91.902  1.00 73.76  ? 91  THR C C   1 
ATOM   4117 O  O   . THR C 3 91  ? 139.626 146.659 90.862  1.00 73.76  ? 91  THR C O   1 
ATOM   4118 C  CB  . THR C 3 91  ? 141.630 148.916 91.301  1.00 73.76  ? 91  THR C CB  1 
ATOM   4119 O  OG1 . THR C 3 91  ? 140.789 149.745 92.115  1.00 73.76  ? 91  THR C OG1 1 
ATOM   4120 C  CG2 . THR C 3 91  ? 141.178 148.964 89.839  1.00 73.76  ? 91  THR C CG2 1 
ATOM   4121 N  N   . ALA C 3 92  ? 139.798 146.555 93.104  1.00 65.04  ? 92  ALA C N   1 
ATOM   4122 C  CA  . ALA C 3 92  ? 138.536 145.849 93.297  1.00 65.04  ? 92  ALA C CA  1 
ATOM   4123 C  C   . ALA C 3 92  ? 138.178 145.923 94.776  1.00 65.04  ? 92  ALA C C   1 
ATOM   4124 O  O   . ALA C 3 92  ? 138.771 146.691 95.541  1.00 65.04  ? 92  ALA C O   1 
ATOM   4125 C  CB  . ALA C 3 92  ? 138.626 144.401 92.814  1.00 65.04  ? 92  ALA C CB  1 
ATOM   4126 N  N   . VAL C 3 93  ? 137.178 145.140 95.169  1.00 61.51  ? 93  VAL C N   1 
ATOM   4127 C  CA  . VAL C 3 93  ? 136.799 144.988 96.568  1.00 61.51  ? 93  VAL C CA  1 
ATOM   4128 C  C   . VAL C 3 93  ? 136.973 143.521 96.938  1.00 61.51  ? 93  VAL C C   1 
ATOM   4129 O  O   . VAL C 3 93  ? 136.373 142.640 96.312  1.00 61.51  ? 93  VAL C O   1 
ATOM   4130 C  CB  . VAL C 3 93  ? 135.359 145.456 96.824  1.00 61.51  ? 93  VAL C CB  1 
ATOM   4131 C  CG1 . VAL C 3 93  ? 135.089 145.533 98.316  1.00 61.51  ? 93  VAL C CG1 1 
ATOM   4132 C  CG2 . VAL C 3 93  ? 135.111 146.803 96.162  1.00 61.51  ? 93  VAL C CG2 1 
ATOM   4133 N  N   . TYR C 3 94  ? 137.788 143.260 97.954  1.00 60.37  ? 94  TYR C N   1 
ATOM   4134 C  CA  . TYR C 3 94  ? 138.053 141.911 98.429  1.00 60.37  ? 94  TYR C CA  1 
ATOM   4135 C  C   . TYR C 3 94  ? 137.266 141.653 99.705  1.00 60.37  ? 94  TYR C C   1 
ATOM   4136 O  O   . TYR C 3 94  ? 137.288 142.466 100.635 1.00 60.37  ? 94  TYR C O   1 
ATOM   4137 C  CB  . TYR C 3 94  ? 139.546 141.698 98.690  1.00 60.37  ? 94  TYR C CB  1 
ATOM   4138 C  CG  . TYR C 3 94  ? 140.433 141.860 97.475  1.00 60.37  ? 94  TYR C CG  1 
ATOM   4139 C  CD1 . TYR C 3 94  ? 140.715 143.114 96.956  1.00 60.37  ? 94  TYR C CD1 1 
ATOM   4140 C  CD2 . TYR C 3 94  ? 140.994 140.754 96.852  1.00 60.37  ? 94  TYR C CD2 1 
ATOM   4141 C  CE1 . TYR C 3 94  ? 141.527 143.264 95.851  1.00 60.37  ? 94  TYR C CE1 1 
ATOM   4142 C  CE2 . TYR C 3 94  ? 141.808 140.895 95.746  1.00 60.37  ? 94  TYR C CE2 1 
ATOM   4143 C  CZ  . TYR C 3 94  ? 142.071 142.152 95.250  1.00 60.37  ? 94  TYR C CZ  1 
ATOM   4144 O  OH  . TYR C 3 94  ? 142.881 142.298 94.148  1.00 60.37  ? 94  TYR C OH  1 
ATOM   4145 N  N   . TYR C 3 95  ? 136.571 140.521 99.745  1.00 60.53  ? 95  TYR C N   1 
ATOM   4146 C  CA  . TYR C 3 95  ? 135.781 140.124 100.898 1.00 60.53  ? 95  TYR C CA  1 
ATOM   4147 C  C   . TYR C 3 95  ? 136.290 138.793 101.429 1.00 60.53  ? 95  TYR C C   1 
ATOM   4148 O  O   . TYR C 3 95  ? 136.758 137.938 100.671 1.00 60.53  ? 95  TYR C O   1 
ATOM   4149 C  CB  . TYR C 3 95  ? 134.285 139.983 100.565 1.00 60.53  ? 95  TYR C CB  1 
ATOM   4150 C  CG  . TYR C 3 95  ? 133.653 141.168 99.869  1.00 60.53  ? 95  TYR C CG  1 
ATOM   4151 C  CD1 . TYR C 3 95  ? 133.908 141.434 98.532  1.00 60.53  ? 95  TYR C CD1 1 
ATOM   4152 C  CD2 . TYR C 3 95  ? 132.784 142.009 100.548 1.00 60.53  ? 95  TYR C CD2 1 
ATOM   4153 C  CE1 . TYR C 3 95  ? 133.325 142.510 97.894  1.00 60.53  ? 95  TYR C CE1 1 
ATOM   4154 C  CE2 . TYR C 3 95  ? 132.197 143.088 99.919  1.00 60.53  ? 95  TYR C CE2 1 
ATOM   4155 C  CZ  . TYR C 3 95  ? 132.470 143.333 98.592  1.00 60.53  ? 95  TYR C CZ  1 
ATOM   4156 O  OH  . TYR C 3 95  ? 131.888 144.408 97.961  1.00 60.53  ? 95  TYR C OH  1 
ATOM   4157 N  N   . CYS C 3 96  ? 136.192 138.627 102.744 1.00 62.98  ? 96  CYS C N   1 
ATOM   4158 C  CA  . CYS C 3 96  ? 136.457 137.356 103.402 1.00 62.98  ? 96  CYS C CA  1 
ATOM   4159 C  C   . CYS C 3 96  ? 135.137 136.782 103.894 1.00 62.98  ? 96  CYS C C   1 
ATOM   4160 O  O   . CYS C 3 96  ? 134.330 137.494 104.502 1.00 62.98  ? 96  CYS C O   1 
ATOM   4161 C  CB  . CYS C 3 96  ? 137.459 137.521 104.552 1.00 62.98  ? 96  CYS C CB  1 
ATOM   4162 S  SG  . CYS C 3 96  ? 136.778 138.083 106.131 1.00 62.98  ? 96  CYS C SG  1 
ATOM   4163 N  N   . ALA C 3 97  ? 134.903 135.509 103.596 1.00 60.57  ? 97  ALA C N   1 
ATOM   4164 C  CA  . ALA C 3 97  ? 133.675 134.826 103.959 1.00 60.57  ? 97  ALA C CA  1 
ATOM   4165 C  C   . ALA C 3 97  ? 134.003 133.553 104.725 1.00 60.57  ? 97  ALA C C   1 
ATOM   4166 O  O   . ALA C 3 97  ? 135.119 133.034 104.663 1.00 60.57  ? 97  ALA C O   1 
ATOM   4167 C  CB  . ALA C 3 97  ? 132.834 134.496 102.721 1.00 60.57  ? 97  ALA C CB  1 
ATOM   4168 N  N   . ARG C 3 98  ? 133.008 133.046 105.444 1.00 63.16  ? 98  ARG C N   1 
ATOM   4169 C  CA  . ARG C 3 98  ? 133.174 131.891 106.309 1.00 63.16  ? 98  ARG C CA  1 
ATOM   4170 C  C   . ARG C 3 98  ? 132.098 130.859 106.000 1.00 63.16  ? 98  ARG C C   1 
ATOM   4171 O  O   . ARG C 3 98  ? 130.981 131.205 105.606 1.00 63.16  ? 98  ARG C O   1 
ATOM   4172 C  CB  . ARG C 3 98  ? 133.107 132.307 107.784 1.00 63.16  ? 98  ARG C CB  1 
ATOM   4173 C  CG  . ARG C 3 98  ? 133.468 131.219 108.775 1.00 63.16  ? 98  ARG C CG  1 
ATOM   4174 C  CD  . ARG C 3 98  ? 133.200 131.676 110.199 1.00 63.16  ? 98  ARG C CD  1 
ATOM   4175 N  NE  . ARG C 3 98  ? 131.775 131.840 110.460 1.00 63.16  ? 98  ARG C NE  1 
ATOM   4176 C  CZ  . ARG C 3 98  ? 131.271 132.367 111.568 1.00 63.16  ? 98  ARG C CZ  1 
ATOM   4177 N  NH1 . ARG C 3 98  ? 132.052 132.795 112.546 1.00 63.16  ? 98  ARG C NH1 1 
ATOM   4178 N  NH2 . ARG C 3 98  ? 129.952 132.466 111.697 1.00 63.16  ? 98  ARG C NH2 1 
ATOM   4179 N  N   . GLY C 3 99  ? 132.446 129.586 106.169 1.00 59.75  ? 99  GLY C N   1 
ATOM   4180 C  CA  . GLY C 3 99  ? 131.485 128.519 105.964 1.00 59.75  ? 99  GLY C CA  1 
ATOM   4181 C  C   . GLY C 3 99  ? 131.753 127.354 106.892 1.00 59.75  ? 99  GLY C C   1 
ATOM   4182 O  O   . GLY C 3 99  ? 132.845 127.216 107.448 1.00 59.75  ? 99  GLY C O   1 
ATOM   4183 N  N   . GLN C 3 100 ? 130.740 126.505 107.042 1.00 59.90  ? 100 GLN C N   1 
ATOM   4184 C  CA  . GLN C 3 100 ? 130.806 125.352 107.931 1.00 59.90  ? 100 GLN C CA  1 
ATOM   4185 C  C   . GLN C 3 100 ? 131.201 124.114 107.135 1.00 59.90  ? 100 GLN C C   1 
ATOM   4186 O  O   . GLN C 3 100 ? 130.472 123.695 106.229 1.00 59.90  ? 100 GLN C O   1 
ATOM   4187 C  CB  . GLN C 3 100 ? 129.468 125.129 108.635 1.00 59.90  ? 100 GLN C CB  1 
ATOM   4188 C  CG  . GLN C 3 100 ? 129.490 124.007 109.659 1.00 59.90  ? 100 GLN C CG  1 
ATOM   4189 C  CD  . GLN C 3 100 ? 130.434 124.289 110.810 1.00 59.90  ? 100 GLN C CD  1 
ATOM   4190 O  OE1 . GLN C 3 100 ? 131.570 123.816 110.826 1.00 59.90  ? 100 GLN C OE1 1 
ATOM   4191 N  NE2 . GLN C 3 100 ? 129.965 125.058 111.785 1.00 59.90  ? 100 GLN C NE2 1 
ATOM   4192 N  N   . LEU C 3 101 ? 132.342 123.527 107.484 1.00 55.85  ? 101 LEU C N   1 
ATOM   4193 C  CA  . LEU C 3 101 ? 132.818 122.335 106.796 1.00 55.85  ? 101 LEU C CA  1 
ATOM   4194 C  C   . LEU C 3 101 ? 131.938 121.137 107.132 1.00 55.85  ? 101 LEU C C   1 
ATOM   4195 O  O   . LEU C 3 101 ? 131.568 120.922 108.290 1.00 55.85  ? 101 LEU C O   1 
ATOM   4196 C  CB  . LEU C 3 101 ? 134.269 122.050 107.181 1.00 55.85  ? 101 LEU C CB  1 
ATOM   4197 C  CG  . LEU C 3 101 ? 134.991 120.958 106.393 1.00 55.85  ? 101 LEU C CG  1 
ATOM   4198 C  CD1 . LEU C 3 101 ? 134.945 121.253 104.902 1.00 55.85  ? 101 LEU C CD1 1 
ATOM   4199 C  CD2 . LEU C 3 101 ? 136.427 120.826 106.869 1.00 55.85  ? 101 LEU C CD2 1 
ATOM   4200 N  N   . ARG C 3 102 ? 131.600 120.353 106.110 1.00 55.47  ? 102 ARG C N   1 
ATOM   4201 C  CA  . ARG C 3 102 ? 130.726 119.200 106.279 1.00 55.47  ? 102 ARG C CA  1 
ATOM   4202 C  C   . ARG C 3 102 ? 131.459 117.867 106.325 1.00 55.47  ? 102 ARG C C   1 
ATOM   4203 O  O   . ARG C 3 102 ? 131.281 117.122 107.290 1.00 55.47  ? 102 ARG C O   1 
ATOM   4204 C  CB  . ARG C 3 102 ? 129.675 119.157 105.159 1.00 55.47  ? 102 ARG C CB  1 
ATOM   4205 C  CG  . ARG C 3 102 ? 128.666 118.034 105.305 1.00 55.47  ? 102 ARG C CG  1 
ATOM   4206 C  CD  . ARG C 3 102 ? 127.530 118.184 104.312 1.00 55.47  ? 102 ARG C CD  1 
ATOM   4207 N  NE  . ARG C 3 102 ? 126.641 119.281 104.675 1.00 55.47  ? 102 ARG C NE  1 
ATOM   4208 C  CZ  . ARG C 3 102 ? 126.319 120.283 103.869 1.00 55.47  ? 102 ARG C CZ  1 
ATOM   4209 N  NH1 . ARG C 3 102 ? 126.802 120.364 102.640 1.00 55.47  ? 102 ARG C NH1 1 
ATOM   4210 N  NH2 . ARG C 3 102 ? 125.492 121.228 104.307 1.00 55.47  ? 102 ARG C NH2 1 
ATOM   4211 N  N   . TYR C 3 103 ? 132.270 117.542 105.320 1.00 54.07  ? 103 TYR C N   1 
ATOM   4212 C  CA  . TYR C 3 103 ? 133.114 116.358 105.393 1.00 54.07  ? 103 TYR C CA  1 
ATOM   4213 C  C   . TYR C 3 103 ? 134.451 116.659 104.733 1.00 54.07  ? 103 TYR C C   1 
ATOM   4214 O  O   . TYR C 3 103 ? 134.584 117.606 103.955 1.00 54.07  ? 103 TYR C O   1 
ATOM   4215 C  CB  . TYR C 3 103 ? 132.462 115.128 104.743 1.00 54.07  ? 103 TYR C CB  1 
ATOM   4216 C  CG  . TYR C 3 103 ? 132.207 115.245 103.254 1.00 54.07  ? 103 TYR C CG  1 
ATOM   4217 C  CD1 . TYR C 3 103 ? 131.009 115.751 102.772 1.00 54.07  ? 103 TYR C CD1 1 
ATOM   4218 C  CD2 . TYR C 3 103 ? 133.176 114.866 102.332 1.00 54.07  ? 103 TYR C CD2 1 
ATOM   4219 C  CE1 . TYR C 3 103 ? 130.776 115.860 101.412 1.00 54.07  ? 103 TYR C CE1 1 
ATOM   4220 C  CE2 . TYR C 3 103 ? 132.954 114.978 100.974 1.00 54.07  ? 103 TYR C CE2 1 
ATOM   4221 C  CZ  . TYR C 3 103 ? 131.753 115.476 100.520 1.00 54.07  ? 103 TYR C CZ  1 
ATOM   4222 O  OH  . TYR C 3 103 ? 131.527 115.586 99.167  1.00 54.07  ? 103 TYR C OH  1 
ATOM   4223 N  N   . PHE C 3 104 ? 135.445 115.838 105.066 1.00 52.82  ? 104 PHE C N   1 
ATOM   4224 C  CA  . PHE C 3 104 ? 136.768 115.957 104.459 1.00 52.82  ? 104 PHE C CA  1 
ATOM   4225 C  C   . PHE C 3 104 ? 137.359 114.559 104.356 1.00 52.82  ? 104 PHE C C   1 
ATOM   4226 O  O   . PHE C 3 104 ? 137.412 113.836 105.356 1.00 52.82  ? 104 PHE C O   1 
ATOM   4227 C  CB  . PHE C 3 104 ? 137.664 116.877 105.278 1.00 52.82  ? 104 PHE C CB  1 
ATOM   4228 C  CG  . PHE C 3 104 ? 138.871 117.369 104.533 1.00 52.82  ? 104 PHE C CG  1 
ATOM   4229 C  CD1 . PHE C 3 104 ? 139.936 116.525 104.274 1.00 52.82  ? 104 PHE C CD1 1 
ATOM   4230 C  CD2 . PHE C 3 104 ? 138.942 118.680 104.094 1.00 52.82  ? 104 PHE C CD2 1 
ATOM   4231 C  CE1 . PHE C 3 104 ? 141.046 116.976 103.590 1.00 52.82  ? 104 PHE C CE1 1 
ATOM   4232 C  CE2 . PHE C 3 104 ? 140.051 119.137 103.409 1.00 52.82  ? 104 PHE C CE2 1 
ATOM   4233 C  CZ  . PHE C 3 104 ? 141.104 118.283 103.157 1.00 52.82  ? 104 PHE C CZ  1 
ATOM   4234 N  N   . ASP C 3 105 ? 137.797 114.184 103.157 1.00 56.88  ? 105 ASP C N   1 
ATOM   4235 C  CA  . ASP C 3 105 ? 138.455 112.905 102.931 1.00 56.88  ? 105 ASP C CA  1 
ATOM   4236 C  C   . ASP C 3 105 ? 139.297 113.008 101.670 1.00 56.88  ? 105 ASP C C   1 
ATOM   4237 O  O   . ASP C 3 105 ? 138.808 113.463 100.631 1.00 56.88  ? 105 ASP C O   1 
ATOM   4238 C  CB  . ASP C 3 105 ? 137.438 111.767 102.806 1.00 56.88  ? 105 ASP C CB  1 
ATOM   4239 C  CG  . ASP C 3 105 ? 138.048 110.411 103.090 1.00 56.88  ? 105 ASP C CG  1 
ATOM   4240 O  OD1 . ASP C 3 105 ? 138.657 110.245 104.167 1.00 56.88  ? 105 ASP C OD1 1 
ATOM   4241 O  OD2 . ASP C 3 105 ? 137.924 109.512 102.234 1.00 56.88  ? 105 ASP C OD2 1 
ATOM   4242 N  N   . TRP C 3 106 ? 140.558 112.593 101.768 1.00 57.27  ? 106 TRP C N   1 
ATOM   4243 C  CA  . TRP C 3 106 ? 141.480 112.759 100.647 1.00 57.27  ? 106 TRP C CA  1 
ATOM   4244 C  C   . TRP C 3 106 ? 141.086 111.982 99.393  1.00 57.27  ? 106 TRP C C   1 
ATOM   4245 O  O   . TRP C 3 106 ? 141.107 112.584 98.305  1.00 57.27  ? 106 TRP C O   1 
ATOM   4246 C  CB  . TRP C 3 106 ? 142.900 112.392 101.092 1.00 57.27  ? 106 TRP C CB  1 
ATOM   4247 C  CG  . TRP C 3 106 ? 143.546 113.446 101.932 1.00 57.27  ? 106 TRP C CG  1 
ATOM   4248 C  CD1 . TRP C 3 106 ? 143.576 113.503 103.294 1.00 57.27  ? 106 TRP C CD1 1 
ATOM   4249 C  CD2 . TRP C 3 106 ? 144.250 114.602 101.466 1.00 57.27  ? 106 TRP C CD2 1 
ATOM   4250 N  NE1 . TRP C 3 106 ? 144.260 114.621 103.706 1.00 57.27  ? 106 TRP C NE1 1 
ATOM   4251 C  CE2 . TRP C 3 106 ? 144.684 115.313 102.602 1.00 57.27  ? 106 TRP C CE2 1 
ATOM   4252 C  CE3 . TRP C 3 106 ? 144.557 115.104 100.198 1.00 57.27  ? 106 TRP C CE3 1 
ATOM   4253 C  CZ2 . TRP C 3 106 ? 145.408 116.498 102.508 1.00 57.27  ? 106 TRP C CZ2 1 
ATOM   4254 C  CZ3 . TRP C 3 106 ? 145.277 116.281 100.107 1.00 57.27  ? 106 TRP C CZ3 1 
ATOM   4255 C  CH2 . TRP C 3 106 ? 145.694 116.965 101.255 1.00 57.27  ? 106 TRP C CH2 1 
ATOM   4256 N  N   . PRO C 3 107 ? 140.742 110.675 99.447  1.00 56.45  ? 107 PRO C N   1 
ATOM   4257 C  CA  . PRO C 3 107 ? 140.416 109.959 98.203  1.00 56.45  ? 107 PRO C CA  1 
ATOM   4258 C  C   . PRO C 3 107 ? 139.250 110.568 97.441  1.00 56.45  ? 107 PRO C C   1 
ATOM   4259 O  O   . PRO C 3 107 ? 139.390 110.926 96.267  1.00 56.45  ? 107 PRO C O   1 
ATOM   4260 C  CB  . PRO C 3 107 ? 140.082 108.544 98.689  1.00 56.45  ? 107 PRO C CB  1 
ATOM   4261 C  CG  . PRO C 3 107 ? 140.787 108.410 99.982  1.00 56.45  ? 107 PRO C CG  1 
ATOM   4262 C  CD  . PRO C 3 107 ? 140.740 109.766 100.609 1.00 56.45  ? 107 PRO C CD  1 
ATOM   4263 N  N   . THR C 3 108 ? 138.096 110.691 98.093  1.00 56.40  ? 108 THR C N   1 
ATOM   4264 C  CA  . THR C 3 108 ? 136.955 111.353 97.479  1.00 56.40  ? 108 THR C CA  1 
ATOM   4265 C  C   . THR C 3 108 ? 137.229 112.852 97.368  1.00 56.40  ? 108 THR C C   1 
ATOM   4266 O  O   . THR C 3 108 ? 138.287 113.351 97.760  1.00 56.40  ? 108 THR C O   1 
ATOM   4267 C  CB  . THR C 3 108 ? 135.685 111.079 98.281  1.00 56.40  ? 108 THR C CB  1 
ATOM   4268 O  OG1 . THR C 3 108 ? 134.545 111.538 97.544  1.00 56.40  ? 108 THR C OG1 1 
ATOM   4269 C  CG2 . THR C 3 108 ? 135.734 111.795 99.617  1.00 56.40  ? 108 THR C CG2 1 
ATOM   4270 N  N   . ILE C 3 109 ? 136.263 113.585 96.821  1.00 55.90  ? 109 ILE C N   1 
ATOM   4271 C  CA  . ILE C 3 109 ? 136.417 115.026 96.640  1.00 55.90  ? 109 ILE C CA  1 
ATOM   4272 C  C   . ILE C 3 109 ? 136.458 115.686 98.013  1.00 55.90  ? 109 ILE C C   1 
ATOM   4273 O  O   . ILE C 3 109 ? 135.482 115.600 98.772  1.00 55.90  ? 109 ILE C O   1 
ATOM   4274 C  CB  . ILE C 3 109 ? 135.287 115.611 95.777  1.00 55.90  ? 109 ILE C CB  1 
ATOM   4275 C  CG1 . ILE C 3 109 ? 135.189 114.866 94.443  1.00 55.90  ? 109 ILE C CG1 1 
ATOM   4276 C  CG2 . ILE C 3 109 ? 135.512 117.095 95.546  1.00 55.90  ? 109 ILE C CG2 1 
ATOM   4277 C  CD1 . ILE C 3 109 ? 134.024 113.904 94.365  1.00 55.90  ? 109 ILE C CD1 1 
ATOM   4278 N  N   . PRO C 3 110 ? 137.556 116.350 98.375  1.00 56.73  ? 110 PRO C N   1 
ATOM   4279 C  CA  . PRO C 3 110 ? 137.645 116.956 99.709  1.00 56.73  ? 110 PRO C CA  1 
ATOM   4280 C  C   . PRO C 3 110 ? 136.995 118.326 99.752  1.00 56.73  ? 110 PRO C C   1 
ATOM   4281 O  O   . PRO C 3 110 ? 136.432 118.779 98.750  1.00 56.73  ? 110 PRO C O   1 
ATOM   4282 C  CB  . PRO C 3 110 ? 139.160 117.048 99.955  1.00 56.73  ? 110 PRO C CB  1 
ATOM   4283 C  CG  . PRO C 3 110 ? 139.817 116.344 98.775  1.00 56.73  ? 110 PRO C CG  1 
ATOM   4284 C  CD  . PRO C 3 110 ? 138.836 116.436 97.659  1.00 56.73  ? 110 PRO C CD  1 
ATOM   4285 N  N   . SER C 3 111 ? 137.072 118.992 100.906 1.00 56.75  ? 111 SER C N   1 
ATOM   4286 C  CA  . SER C 3 111 ? 136.586 120.361 101.074 1.00 56.75  ? 111 SER C CA  1 
ATOM   4287 C  C   . SER C 3 111 ? 135.104 120.457 100.700 1.00 56.75  ? 111 SER C C   1 
ATOM   4288 O  O   . SER C 3 111 ? 134.713 121.095 99.723  1.00 56.75  ? 111 SER C O   1 
ATOM   4289 C  CB  . SER C 3 111 ? 137.433 121.344 100.257 1.00 56.75  ? 111 SER C CB  1 
ATOM   4290 O  OG  . SER C 3 111 ? 138.806 121.235 100.590 1.00 56.75  ? 111 SER C OG  1 
ATOM   4291 N  N   . SER C 3 112 ? 134.292 119.785 101.512 1.00 57.50  ? 112 SER C N   1 
ATOM   4292 C  CA  . SER C 3 112 ? 132.865 119.670 101.256 1.00 57.50  ? 112 SER C CA  1 
ATOM   4293 C  C   . SER C 3 112 ? 132.195 121.040 101.183 1.00 57.50  ? 112 SER C C   1 
ATOM   4294 O  O   . SER C 3 112 ? 132.778 122.074 101.508 1.00 57.50  ? 112 SER C O   1 
ATOM   4295 C  CB  . SER C 3 112 ? 132.190 118.848 102.347 1.00 57.50  ? 112 SER C CB  1 
ATOM   4296 O  OG  . SER C 3 112 ? 130.784 118.839 102.171 1.00 57.50  ? 112 SER C OG  1 
ATOM   4297 N  N   . TYR C 3 113 ? 130.935 121.024 100.749 1.00 60.04  ? 113 TYR C N   1 
ATOM   4298 C  CA  . TYR C 3 113 ? 130.147 122.240 100.614 1.00 60.04  ? 113 TYR C CA  1 
ATOM   4299 C  C   . TYR C 3 113 ? 130.042 122.977 101.943 1.00 60.04  ? 113 TYR C C   1 
ATOM   4300 O  O   . TYR C 3 113 ? 129.402 122.494 102.883 1.00 60.04  ? 113 TYR C O   1 
ATOM   4301 C  CB  . TYR C 3 113 ? 128.751 121.911 100.081 1.00 60.04  ? 113 TYR C CB  1 
ATOM   4302 C  CG  . TYR C 3 113 ? 127.800 123.086 100.079 1.00 60.04  ? 113 TYR C CG  1 
ATOM   4303 C  CD1 . TYR C 3 113 ? 127.835 124.031 99.063  1.00 60.04  ? 113 TYR C CD1 1 
ATOM   4304 C  CD2 . TYR C 3 113 ? 126.865 123.251 101.093 1.00 60.04  ? 113 TYR C CD2 1 
ATOM   4305 C  CE1 . TYR C 3 113 ? 126.967 125.106 99.057  1.00 60.04  ? 113 TYR C CE1 1 
ATOM   4306 C  CE2 . TYR C 3 113 ? 125.995 124.324 101.096 1.00 60.04  ? 113 TYR C CE2 1 
ATOM   4307 C  CZ  . TYR C 3 113 ? 126.050 125.248 100.075 1.00 60.04  ? 113 TYR C CZ  1 
ATOM   4308 O  OH  . TYR C 3 113 ? 125.185 126.318 100.071 1.00 60.04  ? 113 TYR C OH  1 
ATOM   4309 N  N   . TYR C 3 114 ? 130.670 124.149 102.025 1.00 59.77  ? 114 TYR C N   1 
ATOM   4310 C  CA  . TYR C 3 114 ? 130.551 125.022 103.183 1.00 59.77  ? 114 TYR C CA  1 
ATOM   4311 C  C   . TYR C 3 114 ? 129.936 126.375 102.867 1.00 59.77  ? 114 TYR C C   1 
ATOM   4312 O  O   . TYR C 3 114 ? 129.580 127.106 103.792 1.00 59.77  ? 114 TYR C O   1 
ATOM   4313 C  CB  . TYR C 3 114 ? 131.920 125.220 103.852 1.00 59.77  ? 114 TYR C CB  1 
ATOM   4314 C  CG  . TYR C 3 114 ? 133.041 125.644 102.930 1.00 59.77  ? 114 TYR C CG  1 
ATOM   4315 C  CD1 . TYR C 3 114 ? 133.896 124.701 102.377 1.00 59.77  ? 114 TYR C CD1 1 
ATOM   4316 C  CD2 . TYR C 3 114 ? 133.252 126.979 102.617 1.00 59.77  ? 114 TYR C CD2 1 
ATOM   4317 C  CE1 . TYR C 3 114 ? 134.926 125.069 101.540 1.00 59.77  ? 114 TYR C CE1 1 
ATOM   4318 C  CE2 . TYR C 3 114 ? 134.282 127.358 101.776 1.00 59.77  ? 114 TYR C CE2 1 
ATOM   4319 C  CZ  . TYR C 3 114 ? 135.116 126.397 101.241 1.00 59.77  ? 114 TYR C CZ  1 
ATOM   4320 O  OH  . TYR C 3 114 ? 136.145 126.762 100.403 1.00 59.77  ? 114 TYR C OH  1 
ATOM   4321 N  N   . GLY C 3 115 ? 129.796 126.719 101.591 1.00 63.95  ? 115 GLY C N   1 
ATOM   4322 C  CA  . GLY C 3 115 ? 129.044 127.894 101.208 1.00 63.95  ? 115 GLY C CA  1 
ATOM   4323 C  C   . GLY C 3 115 ? 129.705 129.202 101.613 1.00 63.95  ? 115 GLY C C   1 
ATOM   4324 O  O   . GLY C 3 115 ? 130.908 129.293 101.862 1.00 63.95  ? 115 GLY C O   1 
ATOM   4325 N  N   . MET C 3 116 ? 128.871 130.236 101.672 1.00 64.84  ? 116 MET C N   1 
ATOM   4326 C  CA  . MET C 3 116 ? 129.297 131.594 101.986 1.00 64.84  ? 116 MET C CA  1 
ATOM   4327 C  C   . MET C 3 116 ? 128.306 132.239 102.948 1.00 64.84  ? 116 MET C C   1 
ATOM   4328 O  O   . MET C 3 116 ? 127.898 133.390 102.779 1.00 64.84  ? 116 MET C O   1 
ATOM   4329 C  CB  . MET C 3 116 ? 129.404 132.432 100.716 1.00 64.84  ? 116 MET C CB  1 
ATOM   4330 C  CG  . MET C 3 116 ? 130.464 131.981 99.721  1.00 64.84  ? 116 MET C CG  1 
ATOM   4331 S  SD  . MET C 3 116 ? 132.175 132.056 100.262 1.00 64.84  ? 116 MET C SD  1 
ATOM   4332 C  CE  . MET C 3 116 ? 132.963 131.226 98.884  1.00 64.84  ? 116 MET C CE  1 
ATOM   4333 N  N   . ASP C 3 117 ? 127.887 131.492 103.972 1.00 63.86  ? 117 ASP C N   1 
ATOM   4334 C  CA  . ASP C 3 117 ? 126.774 131.929 104.809 1.00 63.86  ? 117 ASP C CA  1 
ATOM   4335 C  C   . ASP C 3 117 ? 127.104 133.136 105.681 1.00 63.86  ? 117 ASP C C   1 
ATOM   4336 O  O   . ASP C 3 117 ? 126.184 133.727 106.254 1.00 63.86  ? 117 ASP C O   1 
ATOM   4337 C  CB  . ASP C 3 117 ? 126.286 130.772 105.686 1.00 63.86  ? 117 ASP C CB  1 
ATOM   4338 C  CG  . ASP C 3 117 ? 127.284 130.384 106.760 1.00 63.86  ? 117 ASP C CG  1 
ATOM   4339 O  OD1 . ASP C 3 117 ? 128.495 130.608 106.564 1.00 63.86  ? 117 ASP C OD1 1 
ATOM   4340 O  OD2 . ASP C 3 117 ? 126.853 129.854 107.805 1.00 63.86  ? 117 ASP C OD2 1 
ATOM   4341 N  N   . VAL C 3 118 ? 128.374 133.515 105.799 1.00 61.15  ? 118 VAL C N   1 
ATOM   4342 C  CA  . VAL C 3 118 ? 128.774 134.688 106.568 1.00 61.15  ? 118 VAL C CA  1 
ATOM   4343 C  C   . VAL C 3 118 ? 129.781 135.480 105.747 1.00 61.15  ? 118 VAL C C   1 
ATOM   4344 O  O   . VAL C 3 118 ? 130.736 134.913 105.207 1.00 61.15  ? 118 VAL C O   1 
ATOM   4345 C  CB  . VAL C 3 118 ? 129.362 134.295 107.940 1.00 61.15  ? 118 VAL C CB  1 
ATOM   4346 C  CG1 . VAL C 3 118 ? 130.210 135.422 108.508 1.00 61.15  ? 118 VAL C CG1 1 
ATOM   4347 C  CG2 . VAL C 3 118 ? 128.249 133.922 108.907 1.00 61.15  ? 118 VAL C CG2 1 
ATOM   4348 N  N   . TRP C 3 119 ? 129.568 136.794 105.651 1.00 60.30  ? 119 TRP C N   1 
ATOM   4349 C  CA  . TRP C 3 119 ? 130.446 137.645 104.857 1.00 60.30  ? 119 TRP C CA  1 
ATOM   4350 C  C   . TRP C 3 119 ? 131.050 138.770 105.689 1.00 60.30  ? 119 TRP C C   1 
ATOM   4351 O  O   . TRP C 3 119 ? 130.854 138.829 106.907 1.00 60.30  ? 119 TRP C O   1 
ATOM   4352 C  CB  . TRP C 3 119 ? 129.688 138.238 103.668 1.00 60.30  ? 119 TRP C CB  1 
ATOM   4353 C  CG  . TRP C 3 119 ? 129.442 137.266 102.562 1.00 60.30  ? 119 TRP C CG  1 
ATOM   4354 C  CD1 . TRP C 3 119 ? 128.530 136.256 102.550 1.00 60.30  ? 119 TRP C CD1 1 
ATOM   4355 C  CD2 . TRP C 3 119 ? 130.124 137.207 101.303 1.00 60.30  ? 119 TRP C CD2 1 
ATOM   4356 N  NE1 . TRP C 3 119 ? 128.596 135.572 101.361 1.00 60.30  ? 119 TRP C NE1 1 
ATOM   4357 C  CE2 . TRP C 3 119 ? 129.568 136.136 100.578 1.00 60.30  ? 119 TRP C CE2 1 
ATOM   4358 C  CE3 . TRP C 3 119 ? 131.149 137.957 100.719 1.00 60.30  ? 119 TRP C CE3 1 
ATOM   4359 C  CZ2 . TRP C 3 119 ? 130.001 135.797 99.300  1.00 60.30  ? 119 TRP C CZ2 1 
ATOM   4360 C  CZ3 . TRP C 3 119 ? 131.577 137.618 99.450  1.00 60.30  ? 119 TRP C CZ3 1 
ATOM   4361 C  CH2 . TRP C 3 119 ? 131.005 136.548 98.755  1.00 60.30  ? 119 TRP C CH2 1 
ATOM   4362 N  N   . GLY C 3 120 ? 131.788 139.666 105.032 1.00 62.29  ? 120 GLY C N   1 
ATOM   4363 C  CA  . GLY C 3 120 ? 132.360 140.830 105.668 1.00 62.29  ? 120 GLY C CA  1 
ATOM   4364 C  C   . GLY C 3 120 ? 132.004 142.104 104.919 1.00 62.29  ? 120 GLY C C   1 
ATOM   4365 O  O   . GLY C 3 120 ? 131.413 142.077 103.837 1.00 62.29  ? 120 GLY C O   1 
ATOM   4366 N  N   . GLN C 3 121 ? 132.384 143.233 105.523 1.00 63.45  ? 121 GLN C N   1 
ATOM   4367 C  CA  . GLN C 3 121 ? 132.058 144.530 104.943 1.00 63.45  ? 121 GLN C CA  1 
ATOM   4368 C  C   . GLN C 3 121 ? 132.860 144.836 103.683 1.00 63.45  ? 121 GLN C C   1 
ATOM   4369 O  O   . GLN C 3 121 ? 132.383 145.598 102.835 1.00 63.45  ? 121 GLN C O   1 
ATOM   4370 C  CB  . GLN C 3 121 ? 132.261 145.644 105.975 1.00 63.45  ? 121 GLN C CB  1 
ATOM   4371 C  CG  . GLN C 3 121 ? 133.708 145.926 106.345 1.00 63.45  ? 121 GLN C CG  1 
ATOM   4372 C  CD  . GLN C 3 121 ? 134.173 145.115 107.538 1.00 63.45  ? 121 GLN C CD  1 
ATOM   4373 O  OE1 . GLN C 3 121 ? 133.544 144.127 107.915 1.00 63.45  ? 121 GLN C OE1 1 
ATOM   4374 N  NE2 . GLN C 3 121 ? 135.281 145.530 108.137 1.00 63.45  ? 121 GLN C NE2 1 
ATOM   4375 N  N   . GLY C 3 122 ? 134.046 144.272 103.538 1.00 60.43  ? 122 GLY C N   1 
ATOM   4376 C  CA  . GLY C 3 122 ? 134.794 144.448 102.313 1.00 60.43  ? 122 GLY C CA  1 
ATOM   4377 C  C   . GLY C 3 122 ? 136.003 145.349 102.499 1.00 60.43  ? 122 GLY C C   1 
ATOM   4378 O  O   . GLY C 3 122 ? 136.066 146.178 103.416 1.00 60.43  ? 122 GLY C O   1 
ATOM   4379 N  N   . THR C 3 123 ? 136.980 145.183 101.610 1.00 64.47  ? 123 THR C N   1 
ATOM   4380 C  CA  . THR C 3 123 ? 138.214 145.960 101.616 1.00 64.47  ? 123 THR C CA  1 
ATOM   4381 C  C   . THR C 3 123 ? 138.491 146.438 100.200 1.00 64.47  ? 123 THR C C   1 
ATOM   4382 O  O   . THR C 3 123 ? 138.699 145.620 99.300  1.00 64.47  ? 123 THR C O   1 
ATOM   4383 C  CB  . THR C 3 123 ? 139.389 145.126 102.134 1.00 64.47  ? 123 THR C CB  1 
ATOM   4384 O  OG1 . THR C 3 123 ? 139.172 144.792 103.509 1.00 64.47  ? 123 THR C OG1 1 
ATOM   4385 C  CG2 . THR C 3 123 ? 140.695 145.888 101.993 1.00 64.47  ? 123 THR C CG2 1 
ATOM   4386 N  N   . THR C 3 124 ? 138.497 147.752 100.001 1.00 67.60  ? 124 THR C N   1 
ATOM   4387 C  CA  . THR C 3 124 ? 138.726 148.327 98.683  1.00 67.60  ? 124 THR C CA  1 
ATOM   4388 C  C   . THR C 3 124 ? 140.221 148.484 98.443  1.00 67.60  ? 124 THR C C   1 
ATOM   4389 O  O   . THR C 3 124 ? 140.929 149.067 99.270  1.00 67.60  ? 124 THR C O   1 
ATOM   4390 C  CB  . THR C 3 124 ? 138.026 149.679 98.552  1.00 67.60  ? 124 THR C CB  1 
ATOM   4391 O  OG1 . THR C 3 124 ? 136.637 149.534 98.873  1.00 67.60  ? 124 THR C OG1 1 
ATOM   4392 C  CG2 . THR C 3 124 ? 138.160 150.213 97.134  1.00 67.60  ? 124 THR C CG2 1 
ATOM   4393 N  N   . VAL C 3 125 ? 140.698 147.964 97.315  1.00 70.33  ? 125 VAL C N   1 
ATOM   4394 C  CA  . VAL C 3 125 ? 142.099 148.070 96.930  1.00 70.33  ? 125 VAL C CA  1 
ATOM   4395 C  C   . VAL C 3 125 ? 142.170 148.773 95.584  1.00 70.33  ? 125 VAL C C   1 
ATOM   4396 O  O   . VAL C 3 125 ? 141.520 148.347 94.622  1.00 70.33  ? 125 VAL C O   1 
ATOM   4397 C  CB  . VAL C 3 125 ? 142.782 146.692 96.859  1.00 70.33  ? 125 VAL C CB  1 
ATOM   4398 C  CG1 . VAL C 3 125 ? 144.209 146.832 96.354  1.00 70.33  ? 125 VAL C CG1 1 
ATOM   4399 C  CG2 . VAL C 3 125 ? 142.758 146.019 98.220  1.00 70.33  ? 125 VAL C CG2 1 
ATOM   4400 N  N   . THR C 3 126 ? 142.954 149.846 95.516  1.00 78.60  ? 126 THR C N   1 
ATOM   4401 C  CA  . THR C 3 126 ? 143.102 150.621 94.294  1.00 78.60  ? 126 THR C CA  1 
ATOM   4402 C  C   . THR C 3 126 ? 144.570 150.684 93.896  1.00 78.60  ? 126 THR C C   1 
ATOM   4403 O  O   . THR C 3 126 ? 145.436 151.024 94.707  1.00 78.60  ? 126 THR C O   1 
ATOM   4404 C  CB  . THR C 3 126 ? 142.544 152.044 94.457  1.00 78.60  ? 126 THR C CB  1 
ATOM   4405 O  OG1 . THR C 3 126 ? 141.150 151.978 94.781  1.00 78.60  ? 126 THR C OG1 1 
ATOM   4406 C  CG2 . THR C 3 126 ? 142.723 152.841 93.173  1.00 78.60  ? 126 THR C CG2 1 
ATOM   4407 N  N   . VAL C 3 127 ? 144.841 150.369 92.633  1.00 83.84  ? 127 VAL C N   1 
ATOM   4408 C  CA  . VAL C 3 127 ? 146.191 150.381 92.085  1.00 83.84  ? 127 VAL C CA  1 
ATOM   4409 C  C   . VAL C 3 127 ? 146.325 151.588 91.169  1.00 83.84  ? 127 VAL C C   1 
ATOM   4410 O  O   . VAL C 3 127 ? 145.539 151.750 90.228  1.00 83.84  ? 127 VAL C O   1 
ATOM   4411 C  CB  . VAL C 3 127 ? 146.510 149.080 91.326  1.00 83.84  ? 127 VAL C CB  1 
ATOM   4412 C  CG1 . VAL C 3 127 ? 147.933 149.115 90.793  1.00 83.84  ? 127 VAL C CG1 1 
ATOM   4413 C  CG2 . VAL C 3 127 ? 146.301 147.876 92.230  1.00 83.84  ? 127 VAL C CG2 1 
ATOM   4414 N  N   . SER C 3 128 ? 147.316 152.432 91.447  1.00 93.83  ? 128 SER C N   1 
ATOM   4415 C  CA  . SER C 3 128 ? 147.559 153.627 90.654  1.00 93.83  ? 128 SER C CA  1 
ATOM   4416 C  C   . SER C 3 128 ? 149.008 154.054 90.832  1.00 93.83  ? 128 SER C C   1 
ATOM   4417 O  O   . SER C 3 128 ? 149.690 153.630 91.769  1.00 93.83  ? 128 SER C O   1 
ATOM   4418 C  CB  . SER C 3 128 ? 146.610 154.767 91.045  1.00 93.83  ? 128 SER C CB  1 
ATOM   4419 O  OG  . SER C 3 128 ? 146.740 155.866 90.161  1.00 93.83  ? 128 SER C OG  1 
ATOM   4420 N  N   . SER C 3 129 ? 149.470 154.903 89.918  1.00 102.19 ? 129 SER C N   1 
ATOM   4421 C  CA  . SER C 3 129 ? 150.837 155.405 89.938  1.00 102.19 ? 129 SER C CA  1 
ATOM   4422 C  C   . SER C 3 129 ? 150.967 156.742 90.659  1.00 102.19 ? 129 SER C C   1 
ATOM   4423 O  O   . SER C 3 129 ? 152.069 157.298 90.712  1.00 102.19 ? 129 SER C O   1 
ATOM   4424 C  CB  . SER C 3 129 ? 151.371 155.534 88.509  1.00 102.19 ? 129 SER C CB  1 
ATOM   4425 O  OG  . SER C 3 129 ? 152.686 156.063 88.503  1.00 102.19 ? 129 SER C OG  1 
ATOM   4426 N  N   . ALA C 3 130 ? 149.878 157.266 91.212  1.00 101.27 ? 130 ALA C N   1 
ATOM   4427 C  CA  . ALA C 3 130 ? 149.915 158.542 91.917  1.00 101.27 ? 130 ALA C CA  1 
ATOM   4428 C  C   . ALA C 3 130 ? 148.831 158.608 92.988  1.00 101.27 ? 130 ALA C C   1 
ATOM   4429 O  O   . ALA C 3 130 ? 148.011 157.698 93.111  1.00 101.27 ? 130 ALA C O   1 
ATOM   4430 C  CB  . ALA C 3 130 ? 149.764 159.695 90.937  1.00 101.27 ? 130 ALA C CB  1 
ATOM   4431 N  N   . GLU D 4 1   ? 151.361 121.623 160.904 1.00 79.91  ? 1   GLU E N   1 
ATOM   4432 C  CA  . GLU D 4 1   ? 149.973 121.226 160.695 1.00 79.91  ? 1   GLU E CA  1 
ATOM   4433 C  C   . GLU D 4 1   ? 149.238 122.247 159.834 1.00 79.91  ? 1   GLU E C   1 
ATOM   4434 O  O   . GLU D 4 1   ? 149.855 123.135 159.244 1.00 79.91  ? 1   GLU E O   1 
ATOM   4435 C  CB  . GLU D 4 1   ? 149.255 121.056 162.035 1.00 79.91  ? 1   GLU E CB  1 
ATOM   4436 C  CG  . GLU D 4 1   ? 149.250 122.308 162.899 1.00 79.91  ? 1   GLU E CG  1 
ATOM   4437 C  CD  . GLU D 4 1   ? 149.052 122.001 164.371 1.00 79.91  ? 1   GLU E CD  1 
ATOM   4438 O  OE1 . GLU D 4 1   ? 149.140 120.814 164.749 1.00 79.91  ? 1   GLU E OE1 1 
ATOM   4439 O  OE2 . GLU D 4 1   ? 148.808 122.947 165.149 1.00 79.91  ? 1   GLU E OE2 1 
ATOM   4440 N  N   . VAL D 4 2   ? 147.914 122.115 159.766 1.00 74.71  ? 2   VAL E N   1 
ATOM   4441 C  CA  . VAL D 4 2   ? 147.103 123.063 159.014 1.00 74.71  ? 2   VAL E CA  1 
ATOM   4442 C  C   . VAL D 4 2   ? 147.079 124.396 159.747 1.00 74.71  ? 2   VAL E C   1 
ATOM   4443 O  O   . VAL D 4 2   ? 146.816 124.457 160.955 1.00 74.71  ? 2   VAL E O   1 
ATOM   4444 C  CB  . VAL D 4 2   ? 145.687 122.507 158.800 1.00 74.71  ? 2   VAL E CB  1 
ATOM   4445 C  CG1 . VAL D 4 2   ? 145.704 121.424 157.733 1.00 74.71  ? 2   VAL E CG1 1 
ATOM   4446 C  CG2 . VAL D 4 2   ? 145.127 121.952 160.102 1.00 74.71  ? 2   VAL E CG2 1 
ATOM   4447 N  N   . GLN D 4 3   ? 147.367 125.474 159.021 1.00 73.51  ? 3   GLN E N   1 
ATOM   4448 C  CA  . GLN D 4 3   ? 147.510 126.786 159.638 1.00 73.51  ? 3   GLN E CA  1 
ATOM   4449 C  C   . GLN D 4 3   ? 147.213 127.875 158.618 1.00 73.51  ? 3   GLN E C   1 
ATOM   4450 O  O   . GLN D 4 3   ? 147.707 127.825 157.487 1.00 73.51  ? 3   GLN E O   1 
ATOM   4451 C  CB  . GLN D 4 3   ? 148.921 126.970 160.208 1.00 73.51  ? 3   GLN E CB  1 
ATOM   4452 C  CG  . GLN D 4 3   ? 149.130 128.281 160.944 1.00 73.51  ? 3   GLN E CG  1 
ATOM   4453 C  CD  . GLN D 4 3   ? 150.592 128.562 161.224 1.00 73.51  ? 3   GLN E CD  1 
ATOM   4454 O  OE1 . GLN D 4 3   ? 151.469 128.173 160.454 1.00 73.51  ? 3   GLN E OE1 1 
ATOM   4455 N  NE2 . GLN D 4 3   ? 150.862 129.241 162.333 1.00 73.51  ? 3   GLN E NE2 1 
ATOM   4456 N  N   . LEU D 4 4   ? 146.405 128.851 159.030 1.00 68.67  ? 4   LEU E N   1 
ATOM   4457 C  CA  . LEU D 4 4   ? 146.119 130.043 158.243 1.00 68.67  ? 4   LEU E CA  1 
ATOM   4458 C  C   . LEU D 4 4   ? 146.449 131.266 159.085 1.00 68.67  ? 4   LEU E C   1 
ATOM   4459 O  O   . LEU D 4 4   ? 145.970 131.391 160.216 1.00 68.67  ? 4   LEU E O   1 
ATOM   4460 C  CB  . LEU D 4 4   ? 144.655 130.084 157.799 1.00 68.67  ? 4   LEU E CB  1 
ATOM   4461 C  CG  . LEU D 4 4   ? 144.078 128.779 157.252 1.00 68.67  ? 4   LEU E CG  1 
ATOM   4462 C  CD1 . LEU D 4 4   ? 142.567 128.867 157.123 1.00 68.67  ? 4   LEU E CD1 1 
ATOM   4463 C  CD2 . LEU D 4 4   ? 144.709 128.438 155.916 1.00 68.67  ? 4   LEU E CD2 1 
ATOM   4464 N  N   . VAL D 4 5   ? 147.264 132.162 158.535 1.00 71.20  ? 5   VAL E N   1 
ATOM   4465 C  CA  . VAL D 4 5   ? 147.728 133.350 159.240 1.00 71.20  ? 5   VAL E CA  1 
ATOM   4466 C  C   . VAL D 4 5   ? 147.262 134.579 158.473 1.00 71.20  ? 5   VAL E C   1 
ATOM   4467 O  O   . VAL D 4 5   ? 147.526 134.703 157.272 1.00 71.20  ? 5   VAL E O   1 
ATOM   4468 C  CB  . VAL D 4 5   ? 149.260 133.354 159.397 1.00 71.20  ? 5   VAL E CB  1 
ATOM   4469 C  CG1 . VAL D 4 5   ? 149.730 134.667 160.004 1.00 71.20  ? 5   VAL E CG1 1 
ATOM   4470 C  CG2 . VAL D 4 5   ? 149.708 132.174 160.245 1.00 71.20  ? 5   VAL E CG2 1 
ATOM   4471 N  N   . GLU D 4 6   ? 146.575 135.483 159.166 1.00 73.24  ? 6   GLU E N   1 
ATOM   4472 C  CA  . GLU D 4 6   ? 146.075 136.716 158.580 1.00 73.24  ? 6   GLU E CA  1 
ATOM   4473 C  C   . GLU D 4 6   ? 146.929 137.896 159.024 1.00 73.24  ? 6   GLU E C   1 
ATOM   4474 O  O   . GLU D 4 6   ? 147.453 137.920 160.142 1.00 73.24  ? 6   GLU E O   1 
ATOM   4475 C  CB  . GLU D 4 6   ? 144.614 136.962 158.969 1.00 73.24  ? 6   GLU E CB  1 
ATOM   4476 C  CG  . GLU D 4 6   ? 143.632 135.987 158.353 1.00 73.24  ? 6   GLU E CG  1 
ATOM   4477 C  CD  . GLU D 4 6   ? 143.302 134.836 159.279 1.00 73.24  ? 6   GLU E CD  1 
ATOM   4478 O  OE1 . GLU D 4 6   ? 144.146 134.499 160.135 1.00 73.24  ? 6   GLU E OE1 1 
ATOM   4479 O  OE2 . GLU D 4 6   ? 142.196 134.270 159.153 1.00 73.24  ? 6   GLU E OE2 1 
ATOM   4480 N  N   . SER D 4 7   ? 147.064 138.878 158.136 1.00 77.96  ? 7   SER E N   1 
ATOM   4481 C  CA  . SER D 4 7   ? 147.864 140.061 158.426 1.00 77.96  ? 7   SER E CA  1 
ATOM   4482 C  C   . SER D 4 7   ? 147.380 141.212 157.556 1.00 77.96  ? 7   SER E C   1 
ATOM   4483 O  O   . SER D 4 7   ? 146.645 141.021 156.585 1.00 77.96  ? 7   SER E O   1 
ATOM   4484 C  CB  . SER D 4 7   ? 149.356 139.795 158.202 1.00 77.96  ? 7   SER E CB  1 
ATOM   4485 O  OG  . SER D 4 7   ? 149.872 138.910 159.181 1.00 77.96  ? 7   SER E OG  1 
ATOM   4486 N  N   . GLY D 4 8   ? 147.803 142.421 157.927 1.00 79.81  ? 8   GLY E N   1 
ATOM   4487 C  CA  . GLY D 4 8   ? 147.518 143.619 157.173 1.00 79.81  ? 8   GLY E CA  1 
ATOM   4488 C  C   . GLY D 4 8   ? 146.250 144.344 157.578 1.00 79.81  ? 8   GLY E C   1 
ATOM   4489 O  O   . GLY D 4 8   ? 146.010 145.456 157.093 1.00 79.81  ? 8   GLY E O   1 
ATOM   4490 N  N   . GLY D 4 9   ? 145.437 143.752 158.447 1.00 77.45  ? 9   GLY E N   1 
ATOM   4491 C  CA  . GLY D 4 9   ? 144.209 144.406 158.862 1.00 77.45  ? 9   GLY E CA  1 
ATOM   4492 C  C   . GLY D 4 9   ? 144.474 145.491 159.891 1.00 77.45  ? 9   GLY E C   1 
ATOM   4493 O  O   . GLY D 4 9   ? 145.253 145.315 160.829 1.00 77.45  ? 9   GLY E O   1 
ATOM   4494 N  N   . ARG D 4 10  ? 143.810 146.630 159.707 1.00 79.62  ? 10  ARG E N   1 
ATOM   4495 C  CA  . ARG D 4 10  ? 143.957 147.760 160.613 1.00 79.62  ? 10  ARG E CA  1 
ATOM   4496 C  C   . ARG D 4 10  ? 142.764 148.685 160.432 1.00 79.62  ? 10  ARG E C   1 
ATOM   4497 O  O   . ARG D 4 10  ? 142.015 148.581 159.458 1.00 79.62  ? 10  ARG E O   1 
ATOM   4498 C  CB  . ARG D 4 10  ? 145.263 148.520 160.364 1.00 79.62  ? 10  ARG E CB  1 
ATOM   4499 C  CG  . ARG D 4 10  ? 145.304 149.243 159.029 1.00 79.62  ? 10  ARG E CG  1 
ATOM   4500 C  CD  . ARG D 4 10  ? 146.653 149.898 158.786 1.00 79.62  ? 10  ARG E CD  1 
ATOM   4501 N  NE  . ARG D 4 10  ? 146.862 150.199 157.375 1.00 79.62  ? 10  ARG E NE  1 
ATOM   4502 C  CZ  . ARG D 4 10  ? 146.367 151.261 156.754 1.00 79.62  ? 10  ARG E CZ  1 
ATOM   4503 N  NH1 . ARG D 4 10  ? 145.626 152.152 157.391 1.00 79.62  ? 10  ARG E NH1 1 
ATOM   4504 N  NH2 . ARG D 4 10  ? 146.623 151.433 155.460 1.00 79.62  ? 10  ARG E NH2 1 
ATOM   4505 N  N   . ALA D 4 11  ? 142.594 149.589 161.392 1.00 76.77  ? 11  ALA E N   1 
ATOM   4506 C  CA  . ALA D 4 11  ? 141.571 150.617 161.273 1.00 76.77  ? 11  ALA E CA  1 
ATOM   4507 C  C   . ALA D 4 11  ? 141.960 151.612 160.187 1.00 76.77  ? 11  ALA E C   1 
ATOM   4508 O  O   . ALA D 4 11  ? 143.142 151.920 160.009 1.00 76.77  ? 11  ALA E O   1 
ATOM   4509 C  CB  . ALA D 4 11  ? 141.377 151.333 162.608 1.00 76.77  ? 11  ALA E CB  1 
ATOM   4510 N  N   . LEU D 4 12  ? 140.965 152.115 159.457 1.00 79.60  ? 12  LEU E N   1 
ATOM   4511 C  CA  . LEU D 4 12  ? 141.236 153.079 158.397 1.00 79.60  ? 12  LEU E CA  1 
ATOM   4512 C  C   . LEU D 4 12  ? 140.093 154.075 158.249 1.00 79.60  ? 12  LEU E C   1 
ATOM   4513 O  O   . LEU D 4 12  ? 139.034 153.917 158.866 1.00 79.60  ? 12  LEU E O   1 
ATOM   4514 C  CB  . LEU D 4 12  ? 141.494 152.365 157.066 1.00 79.60  ? 12  LEU E CB  1 
ATOM   4515 C  CG  . LEU D 4 12  ? 140.318 151.772 156.286 1.00 79.60  ? 12  LEU E CG  1 
ATOM   4516 C  CD1 . LEU D 4 12  ? 140.741 151.486 154.855 1.00 79.60  ? 12  LEU E CD1 1 
ATOM   4517 C  CD2 . LEU D 4 12  ? 139.792 150.509 156.942 1.00 79.60  ? 12  LEU E CD2 1 
ATOM   4518 N  N   . ARG D 4 13  ? 140.302 155.100 157.431 1.00 83.04  ? 13  ARG E N   1 
ATOM   4519 C  CA  . ARG D 4 13  ? 139.372 156.197 157.231 1.00 83.04  ? 13  ARG E CA  1 
ATOM   4520 C  C   . ARG D 4 13  ? 138.588 156.001 155.939 1.00 83.04  ? 13  ARG E C   1 
ATOM   4521 O  O   . ARG D 4 13  ? 139.043 155.299 155.028 1.00 83.04  ? 13  ARG E O   1 
ATOM   4522 C  CB  . ARG D 4 13  ? 140.128 157.534 157.190 1.00 83.04  ? 13  ARG E CB  1 
ATOM   4523 C  CG  . ARG D 4 13  ? 141.060 157.735 158.374 1.00 83.04  ? 13  ARG E CG  1 
ATOM   4524 C  CD  . ARG D 4 13  ? 141.877 159.009 158.243 1.00 83.04  ? 13  ARG E CD  1 
ATOM   4525 N  NE  . ARG D 4 13  ? 142.747 159.209 159.396 1.00 83.04  ? 13  ARG E NE  1 
ATOM   4526 C  CZ  . ARG D 4 13  ? 143.469 160.301 159.610 1.00 83.04  ? 13  ARG E CZ  1 
ATOM   4527 N  NH1 . ARG D 4 13  ? 143.449 161.319 158.766 1.00 83.04  ? 13  ARG E NH1 1 
ATOM   4528 N  NH2 . ARG D 4 13  ? 144.229 160.372 160.699 1.00 83.04  ? 13  ARG E NH2 1 
ATOM   4529 N  N   . PRO D 4 14  ? 137.396 156.592 155.832 1.00 79.91  ? 14  PRO E N   1 
ATOM   4530 C  CA  . PRO D 4 14  ? 136.601 156.428 154.609 1.00 79.91  ? 14  PRO E CA  1 
ATOM   4531 C  C   . PRO D 4 14  ? 137.332 156.964 153.387 1.00 79.91  ? 14  PRO E C   1 
ATOM   4532 O  O   . PRO D 4 14  ? 138.062 157.954 153.458 1.00 79.91  ? 14  PRO E O   1 
ATOM   4533 C  CB  . PRO D 4 14  ? 135.329 157.232 154.901 1.00 79.91  ? 14  PRO E CB  1 
ATOM   4534 C  CG  . PRO D 4 14  ? 135.249 157.289 156.387 1.00 79.91  ? 14  PRO E CG  1 
ATOM   4535 C  CD  . PRO D 4 14  ? 136.668 157.351 156.863 1.00 79.91  ? 14  PRO E CD  1 
ATOM   4536 N  N   . GLY D 4 15  ? 137.126 156.293 152.256 1.00 81.12  ? 15  GLY E N   1 
ATOM   4537 C  CA  . GLY D 4 15  ? 137.798 156.652 151.026 1.00 81.12  ? 15  GLY E CA  1 
ATOM   4538 C  C   . GLY D 4 15  ? 139.203 156.115 150.880 1.00 81.12  ? 15  GLY E C   1 
ATOM   4539 O  O   . GLY D 4 15  ? 139.893 156.486 149.924 1.00 81.12  ? 15  GLY E O   1 
ATOM   4540 N  N   . GLY D 4 16  ? 139.652 155.255 151.796 1.00 82.17  ? 16  GLY E N   1 
ATOM   4541 C  CA  . GLY D 4 16  ? 140.977 154.683 151.735 1.00 82.17  ? 16  GLY E CA  1 
ATOM   4542 C  C   . GLY D 4 16  ? 140.991 153.305 151.086 1.00 82.17  ? 16  GLY E C   1 
ATOM   4543 O  O   . GLY D 4 16  ? 139.984 152.791 150.605 1.00 82.17  ? 16  GLY E O   1 
ATOM   4544 N  N   . SER D 4 17  ? 142.180 152.707 151.081 1.00 81.39  ? 17  SER E N   1 
ATOM   4545 C  CA  . SER D 4 17  ? 142.394 151.384 150.512 1.00 81.39  ? 17  SER E CA  1 
ATOM   4546 C  C   . SER D 4 17  ? 143.177 150.537 151.502 1.00 81.39  ? 17  SER E C   1 
ATOM   4547 O  O   . SER D 4 17  ? 144.137 151.018 152.112 1.00 81.39  ? 17  SER E O   1 
ATOM   4548 C  CB  . SER D 4 17  ? 143.142 151.469 149.176 1.00 81.39  ? 17  SER E CB  1 
ATOM   4549 O  OG  . SER D 4 17  ? 143.341 150.180 148.621 1.00 81.39  ? 17  SER E OG  1 
ATOM   4550 N  N   . LEU D 4 18  ? 142.766 149.280 151.660 1.00 78.35  ? 18  LEU E N   1 
ATOM   4551 C  CA  . LEU D 4 18  ? 143.427 148.362 152.575 1.00 78.35  ? 18  LEU E CA  1 
ATOM   4552 C  C   . LEU D 4 18  ? 143.632 147.019 151.890 1.00 78.35  ? 18  LEU E C   1 
ATOM   4553 O  O   . LEU D 4 18  ? 142.855 146.625 151.018 1.00 78.35  ? 18  LEU E O   1 
ATOM   4554 C  CB  . LEU D 4 18  ? 142.621 148.171 153.866 1.00 78.35  ? 18  LEU E CB  1 
ATOM   4555 C  CG  . LEU D 4 18  ? 143.412 147.725 155.098 1.00 78.35  ? 18  LEU E CG  1 
ATOM   4556 C  CD1 . LEU D 4 18  ? 144.721 148.492 155.211 1.00 78.35  ? 18  LEU E CD1 1 
ATOM   4557 C  CD2 . LEU D 4 18  ? 142.578 147.888 156.357 1.00 78.35  ? 18  LEU E CD2 1 
ATOM   4558 N  N   . ARG D 4 19  ? 144.688 146.318 152.300 1.00 76.81  ? 19  ARG E N   1 
ATOM   4559 C  CA  . ARG D 4 19  ? 145.018 145.003 151.765 1.00 76.81  ? 19  ARG E CA  1 
ATOM   4560 C  C   . ARG D 4 19  ? 145.179 144.027 152.920 1.00 76.81  ? 19  ARG E C   1 
ATOM   4561 O  O   . ARG D 4 19  ? 145.951 144.283 153.849 1.00 76.81  ? 19  ARG E O   1 
ATOM   4562 C  CB  . ARG D 4 19  ? 146.295 145.053 150.920 1.00 76.81  ? 19  ARG E CB  1 
ATOM   4563 C  CG  . ARG D 4 19  ? 146.839 143.688 150.539 1.00 76.81  ? 19  ARG E CG  1 
ATOM   4564 C  CD  . ARG D 4 19  ? 148.047 143.808 149.626 1.00 76.81  ? 19  ARG E CD  1 
ATOM   4565 N  NE  . ARG D 4 19  ? 148.123 142.701 148.679 1.00 76.81  ? 19  ARG E NE  1 
ATOM   4566 C  CZ  . ARG D 4 19  ? 149.066 142.568 147.757 1.00 76.81  ? 19  ARG E CZ  1 
ATOM   4567 N  NH1 . ARG D 4 19  ? 150.036 143.458 147.626 1.00 76.81  ? 19  ARG E NH1 1 
ATOM   4568 N  NH2 . ARG D 4 19  ? 149.034 141.516 146.944 1.00 76.81  ? 19  ARG E NH2 1 
ATOM   4569 N  N   . LEU D 4 20  ? 144.454 142.914 152.859 1.00 73.21  ? 20  LEU E N   1 
ATOM   4570 C  CA  . LEU D 4 20  ? 144.515 141.860 153.861 1.00 73.21  ? 20  LEU E CA  1 
ATOM   4571 C  C   . LEU D 4 20  ? 145.138 140.623 153.232 1.00 73.21  ? 20  LEU E C   1 
ATOM   4572 O  O   . LEU D 4 20  ? 144.699 140.179 152.163 1.00 73.21  ? 20  LEU E O   1 
ATOM   4573 C  CB  . LEU D 4 20  ? 143.121 141.537 154.404 1.00 73.21  ? 20  LEU E CB  1 
ATOM   4574 C  CG  . LEU D 4 20  ? 142.410 142.619 155.221 1.00 73.21  ? 20  LEU E CG  1 
ATOM   4575 C  CD1 . LEU D 4 20  ? 141.626 143.563 154.320 1.00 73.21  ? 20  LEU E CD1 1 
ATOM   4576 C  CD2 . LEU D 4 20  ? 141.493 141.987 156.253 1.00 73.21  ? 20  LEU E CD2 1 
ATOM   4577 N  N   . SER D 4 21  ? 146.152 140.070 153.894 1.00 74.24  ? 21  SER E N   1 
ATOM   4578 C  CA  . SER D 4 21  ? 146.919 138.946 153.378 1.00 74.24  ? 21  SER E CA  1 
ATOM   4579 C  C   . SER D 4 21  ? 146.702 137.713 154.244 1.00 74.24  ? 21  SER E C   1 
ATOM   4580 O  O   . SER D 4 21  ? 146.601 137.810 155.472 1.00 74.24  ? 21  SER E O   1 
ATOM   4581 C  CB  . SER D 4 21  ? 148.412 139.283 153.318 1.00 74.24  ? 21  SER E CB  1 
ATOM   4582 O  OG  . SER D 4 21  ? 148.622 140.565 152.753 1.00 74.24  ? 21  SER E OG  1 
ATOM   4583 N  N   . CYS D 4 22  ? 146.628 136.556 153.590 1.00 70.89  ? 22  CYS E N   1 
ATOM   4584 C  CA  . CYS D 4 22  ? 146.404 135.270 154.239 1.00 70.89  ? 22  CYS E CA  1 
ATOM   4585 C  C   . CYS D 4 22  ? 147.444 134.284 153.733 1.00 70.89  ? 22  CYS E C   1 
ATOM   4586 O  O   . CYS D 4 22  ? 147.596 134.109 152.520 1.00 70.89  ? 22  CYS E O   1 
ATOM   4587 C  CB  . CYS D 4 22  ? 144.992 134.754 153.950 1.00 70.89  ? 22  CYS E CB  1 
ATOM   4588 S  SG  . CYS D 4 22  ? 144.638 133.107 154.591 1.00 70.89  ? 22  CYS E SG  1 
ATOM   4589 N  N   . ALA D 4 23  ? 148.150 133.642 154.658 1.00 72.03  ? 23  ALA E N   1 
ATOM   4590 C  CA  . ALA D 4 23  ? 149.164 132.648 154.338 1.00 72.03  ? 23  ALA E CA  1 
ATOM   4591 C  C   . ALA D 4 23  ? 148.719 131.291 154.864 1.00 72.03  ? 23  ALA E C   1 
ATOM   4592 O  O   . ALA D 4 23  ? 148.329 131.172 156.030 1.00 72.03  ? 23  ALA E O   1 
ATOM   4593 C  CB  . ALA D 4 23  ? 150.519 133.032 154.935 1.00 72.03  ? 23  ALA E CB  1 
ATOM   4594 N  N   . ALA D 4 24  ? 148.783 130.275 154.008 1.00 72.82  ? 24  ALA E N   1 
ATOM   4595 C  CA  . ALA D 4 24  ? 148.336 128.933 154.345 1.00 72.82  ? 24  ALA E CA  1 
ATOM   4596 C  C   . ALA D 4 24  ? 149.517 127.975 154.357 1.00 72.82  ? 24  ALA E C   1 
ATOM   4597 O  O   . ALA D 4 24  ? 150.432 128.078 153.534 1.00 72.82  ? 24  ALA E O   1 
ATOM   4598 C  CB  . ALA D 4 24  ? 147.277 128.435 153.356 1.00 72.82  ? 24  ALA E CB  1 
ATOM   4599 N  N   . SER D 4 25  ? 149.490 127.038 155.301 1.00 72.43  ? 25  SER E N   1 
ATOM   4600 C  CA  . SER D 4 25  ? 150.550 126.045 155.397 1.00 72.43  ? 25  SER E CA  1 
ATOM   4601 C  C   . SER D 4 25  ? 149.979 124.756 155.967 1.00 72.43  ? 25  SER E C   1 
ATOM   4602 O  O   . SER D 4 25  ? 149.043 124.778 156.770 1.00 72.43  ? 25  SER E O   1 
ATOM   4603 C  CB  . SER D 4 25  ? 151.710 126.545 156.265 1.00 72.43  ? 25  SER E CB  1 
ATOM   4604 O  OG  . SER D 4 25  ? 152.421 127.584 155.613 1.00 72.43  ? 25  SER E OG  1 
ATOM   4605 N  N   . GLY D 4 26  ? 150.553 123.636 155.539 1.00 71.57  ? 26  GLY E N   1 
ATOM   4606 C  CA  . GLY D 4 26  ? 150.172 122.336 156.048 1.00 71.57  ? 26  GLY E CA  1 
ATOM   4607 C  C   . GLY D 4 26  ? 149.238 121.527 155.178 1.00 71.57  ? 26  GLY E C   1 
ATOM   4608 O  O   . GLY D 4 26  ? 148.811 120.447 155.604 1.00 71.57  ? 26  GLY E O   1 
ATOM   4609 N  N   . PHE D 4 27  ? 148.908 122.001 153.981 1.00 66.27  ? 27  PHE E N   1 
ATOM   4610 C  CA  . PHE D 4 27  ? 148.008 121.277 153.093 1.00 66.27  ? 27  PHE E CA  1 
ATOM   4611 C  C   . PHE D 4 27  ? 148.274 121.722 151.660 1.00 66.27  ? 27  PHE E C   1 
ATOM   4612 O  O   . PHE D 4 27  ? 149.131 122.572 151.400 1.00 66.27  ? 27  PHE E O   1 
ATOM   4613 C  CB  . PHE D 4 27  ? 146.544 121.491 153.492 1.00 66.27  ? 27  PHE E CB  1 
ATOM   4614 C  CG  . PHE D 4 27  ? 146.081 122.916 153.373 1.00 66.27  ? 27  PHE E CG  1 
ATOM   4615 C  CD1 . PHE D 4 27  ? 146.207 123.789 154.439 1.00 66.27  ? 27  PHE E CD1 1 
ATOM   4616 C  CD2 . PHE D 4 27  ? 145.506 123.378 152.201 1.00 66.27  ? 27  PHE E CD2 1 
ATOM   4617 C  CE1 . PHE D 4 27  ? 145.779 125.098 154.336 1.00 66.27  ? 27  PHE E CE1 1 
ATOM   4618 C  CE2 . PHE D 4 27  ? 145.079 124.686 152.090 1.00 66.27  ? 27  PHE E CE2 1 
ATOM   4619 C  CZ  . PHE D 4 27  ? 145.214 125.546 153.160 1.00 66.27  ? 27  PHE E CZ  1 
ATOM   4620 N  N   . LYS D 4 28  ? 147.529 121.133 150.727 1.00 68.88  ? 28  LYS E N   1 
ATOM   4621 C  CA  . LYS D 4 28  ? 147.670 121.458 149.314 1.00 68.88  ? 28  LYS E CA  1 
ATOM   4622 C  C   . LYS D 4 28  ? 146.965 122.778 149.026 1.00 68.88  ? 28  LYS E C   1 
ATOM   4623 O  O   . LYS D 4 28  ? 145.732 122.855 149.079 1.00 68.88  ? 28  LYS E O   1 
ATOM   4624 C  CB  . LYS D 4 28  ? 147.100 120.337 148.449 1.00 68.88  ? 28  LYS E CB  1 
ATOM   4625 C  CG  . LYS D 4 28  ? 147.545 120.390 146.998 1.00 68.88  ? 28  LYS E CG  1 
ATOM   4626 C  CD  . LYS D 4 28  ? 149.039 120.143 146.871 1.00 68.88  ? 28  LYS E CD  1 
ATOM   4627 C  CE  . LYS D 4 28  ? 149.479 120.148 145.417 1.00 68.88  ? 28  LYS E CE  1 
ATOM   4628 N  NZ  . LYS D 4 28  ? 149.409 121.510 144.821 1.00 68.88  ? 28  LYS E NZ  1 
ATOM   4629 N  N   . PHE D 4 29  ? 147.749 123.813 148.723 1.00 69.06  ? 29  PHE E N   1 
ATOM   4630 C  CA  . PHE D 4 29  ? 147.197 125.148 148.519 1.00 69.06  ? 29  PHE E CA  1 
ATOM   4631 C  C   . PHE D 4 29  ? 146.284 125.214 147.300 1.00 69.06  ? 29  PHE E C   1 
ATOM   4632 O  O   . PHE D 4 29  ? 145.203 125.810 147.364 1.00 69.06  ? 29  PHE E O   1 
ATOM   4633 C  CB  . PHE D 4 29  ? 148.334 126.162 148.381 1.00 69.06  ? 29  PHE E CB  1 
ATOM   4634 C  CG  . PHE D 4 29  ? 147.909 127.587 148.592 1.00 69.06  ? 29  PHE E CG  1 
ATOM   4635 C  CD1 . PHE D 4 29  ? 147.361 128.323 147.556 1.00 69.06  ? 29  PHE E CD1 1 
ATOM   4636 C  CD2 . PHE D 4 29  ? 148.068 128.195 149.825 1.00 69.06  ? 29  PHE E CD2 1 
ATOM   4637 C  CE1 . PHE D 4 29  ? 146.970 129.633 147.746 1.00 69.06  ? 29  PHE E CE1 1 
ATOM   4638 C  CE2 . PHE D 4 29  ? 147.681 129.507 150.022 1.00 69.06  ? 29  PHE E CE2 1 
ATOM   4639 C  CZ  . PHE D 4 29  ? 147.131 130.226 148.980 1.00 69.06  ? 29  PHE E CZ  1 
ATOM   4640 N  N   . ASP D 4 30  ? 146.692 124.606 146.190 1.00 67.54  ? 30  ASP E N   1 
ATOM   4641 C  CA  . ASP D 4 30  ? 146.019 124.788 144.911 1.00 67.54  ? 30  ASP E CA  1 
ATOM   4642 C  C   . ASP D 4 30  ? 144.876 123.810 144.680 1.00 67.54  ? 30  ASP E C   1 
ATOM   4643 O  O   . ASP D 4 30  ? 144.291 123.814 143.592 1.00 67.54  ? 30  ASP E O   1 
ATOM   4644 C  CB  . ASP D 4 30  ? 147.031 124.671 143.767 1.00 67.54  ? 30  ASP E CB  1 
ATOM   4645 C  CG  . ASP D 4 30  ? 146.716 125.603 142.615 1.00 67.54  ? 30  ASP E CG  1 
ATOM   4646 O  OD1 . ASP D 4 30  ? 145.833 126.472 142.776 1.00 67.54  ? 30  ASP E OD1 1 
ATOM   4647 O  OD2 . ASP D 4 30  ? 147.351 125.468 141.548 1.00 67.54  ? 30  ASP E OD2 1 
ATOM   4648 N  N   . ASP D 4 31  ? 144.544 122.969 145.660 1.00 65.14  ? 31  ASP E N   1 
ATOM   4649 C  CA  . ASP D 4 31  ? 143.457 122.007 145.516 1.00 65.14  ? 31  ASP E CA  1 
ATOM   4650 C  C   . ASP D 4 31  ? 142.268 122.342 146.410 1.00 65.14  ? 31  ASP E C   1 
ATOM   4651 O  O   . ASP D 4 31  ? 141.463 121.458 146.719 1.00 65.14  ? 31  ASP E O   1 
ATOM   4652 C  CB  . ASP D 4 31  ? 143.954 120.589 145.803 1.00 65.14  ? 31  ASP E CB  1 
ATOM   4653 C  CG  . ASP D 4 31  ? 144.879 120.066 144.721 1.00 65.14  ? 31  ASP E CG  1 
ATOM   4654 O  OD1 . ASP D 4 31  ? 145.030 120.749 143.686 1.00 65.14  ? 31  ASP E OD1 1 
ATOM   4655 O  OD2 . ASP D 4 31  ? 145.452 118.972 144.903 1.00 65.14  ? 31  ASP E OD2 1 
ATOM   4656 N  N   . TYR D 4 32  ? 142.140 123.597 146.835 1.00 62.55  ? 32  TYR E N   1 
ATOM   4657 C  CA  . TYR D 4 32  ? 141.057 124.006 147.716 1.00 62.55  ? 32  TYR E CA  1 
ATOM   4658 C  C   . TYR D 4 32  ? 140.636 125.430 147.386 1.00 62.55  ? 32  TYR E C   1 
ATOM   4659 O  O   . TYR D 4 32  ? 141.439 126.235 146.907 1.00 62.55  ? 32  TYR E O   1 
ATOM   4660 C  CB  . TYR D 4 32  ? 141.472 123.919 149.190 1.00 62.55  ? 32  TYR E CB  1 
ATOM   4661 C  CG  . TYR D 4 32  ? 141.441 122.520 149.760 1.00 62.55  ? 32  TYR E CG  1 
ATOM   4662 C  CD1 . TYR D 4 32  ? 140.237 121.869 149.989 1.00 62.55  ? 32  TYR E CD1 1 
ATOM   4663 C  CD2 . TYR D 4 32  ? 142.617 121.852 150.069 1.00 62.55  ? 32  TYR E CD2 1 
ATOM   4664 C  CE1 . TYR D 4 32  ? 140.205 120.591 150.510 1.00 62.55  ? 32  TYR E CE1 1 
ATOM   4665 C  CE2 . TYR D 4 32  ? 142.596 120.574 150.591 1.00 62.55  ? 32  TYR E CE2 1 
ATOM   4666 C  CZ  . TYR D 4 32  ? 141.387 119.948 150.809 1.00 62.55  ? 32  TYR E CZ  1 
ATOM   4667 O  OH  . TYR D 4 32  ? 141.361 118.674 151.328 1.00 62.55  ? 32  TYR E OH  1 
ATOM   4668 N  N   . ALA D 4 33  ? 139.368 125.733 147.647 1.00 60.44  ? 33  ALA E N   1 
ATOM   4669 C  CA  . ALA D 4 33  ? 138.892 127.101 147.532 1.00 60.44  ? 33  ALA E CA  1 
ATOM   4670 C  C   . ALA D 4 33  ? 139.293 127.894 148.772 1.00 60.44  ? 33  ALA E C   1 
ATOM   4671 O  O   . ALA D 4 33  ? 139.647 127.329 149.808 1.00 60.44  ? 33  ALA E O   1 
ATOM   4672 C  CB  . ALA D 4 33  ? 137.375 127.130 147.348 1.00 60.44  ? 33  ALA E CB  1 
ATOM   4673 N  N   . MET D 4 34  ? 139.235 129.220 148.665 1.00 61.66  ? 34  MET E N   1 
ATOM   4674 C  CA  . MET D 4 34  ? 139.551 130.068 149.810 1.00 61.66  ? 34  MET E CA  1 
ATOM   4675 C  C   . MET D 4 34  ? 138.625 131.273 149.838 1.00 61.66  ? 34  MET E C   1 
ATOM   4676 O  O   . MET D 4 34  ? 138.305 131.842 148.792 1.00 61.66  ? 34  MET E O   1 
ATOM   4677 C  CB  . MET D 4 34  ? 141.018 130.520 149.790 1.00 61.66  ? 34  MET E CB  1 
ATOM   4678 C  CG  . MET D 4 34  ? 141.999 129.382 150.007 1.00 61.66  ? 34  MET E CG  1 
ATOM   4679 S  SD  . MET D 4 34  ? 143.737 129.838 149.988 1.00 61.66  ? 34  MET E SD  1 
ATOM   4680 C  CE  . MET D 4 34  ? 144.476 128.218 150.177 1.00 61.66  ? 34  MET E CE  1 
ATOM   4681 N  N   . SER D 4 35  ? 138.204 131.664 151.041 1.00 62.93  ? 35  SER E N   1 
ATOM   4682 C  CA  . SER D 4 35  ? 137.244 132.745 151.197 1.00 62.93  ? 35  SER E CA  1 
ATOM   4683 C  C   . SER D 4 35  ? 137.573 133.561 152.439 1.00 62.93  ? 35  SER E C   1 
ATOM   4684 O  O   . SER D 4 35  ? 138.408 133.180 153.265 1.00 62.93  ? 35  SER E O   1 
ATOM   4685 C  CB  . SER D 4 35  ? 135.810 132.208 151.280 1.00 62.93  ? 35  SER E CB  1 
ATOM   4686 O  OG  . SER D 4 35  ? 135.576 131.218 150.296 1.00 62.93  ? 35  SER E OG  1 
ATOM   4687 N  N   . TRP D 4 36  ? 136.908 134.707 152.551 1.00 63.11  ? 36  TRP E N   1 
ATOM   4688 C  CA  . TRP D 4 36  ? 136.963 135.556 153.730 1.00 63.11  ? 36  TRP E CA  1 
ATOM   4689 C  C   . TRP D 4 36  ? 135.573 135.637 154.345 1.00 63.11  ? 36  TRP E C   1 
ATOM   4690 O  O   . TRP D 4 36  ? 134.573 135.717 153.626 1.00 63.11  ? 36  TRP E O   1 
ATOM   4691 C  CB  . TRP D 4 36  ? 137.452 136.964 153.380 1.00 63.11  ? 36  TRP E CB  1 
ATOM   4692 C  CG  . TRP D 4 36  ? 138.814 137.007 152.776 1.00 63.11  ? 36  TRP E CG  1 
ATOM   4693 C  CD1 . TRP D 4 36  ? 139.134 136.814 151.467 1.00 63.11  ? 36  TRP E CD1 1 
ATOM   4694 C  CD2 . TRP D 4 36  ? 140.045 137.272 153.456 1.00 63.11  ? 36  TRP E CD2 1 
ATOM   4695 N  NE1 . TRP D 4 36  ? 140.489 136.938 151.288 1.00 63.11  ? 36  TRP E NE1 1 
ATOM   4696 C  CE2 . TRP D 4 36  ? 141.072 137.218 152.496 1.00 63.11  ? 36  TRP E CE2 1 
ATOM   4697 C  CE3 . TRP D 4 36  ? 140.379 137.546 154.785 1.00 63.11  ? 36  TRP E CE3 1 
ATOM   4698 C  CZ2 . TRP D 4 36  ? 142.409 137.428 152.821 1.00 63.11  ? 36  TRP E CZ2 1 
ATOM   4699 C  CZ3 . TRP D 4 36  ? 141.706 137.754 155.106 1.00 63.11  ? 36  TRP E CZ3 1 
ATOM   4700 C  CH2 . TRP D 4 36  ? 142.705 137.693 154.129 1.00 63.11  ? 36  TRP E CH2 1 
ATOM   4701 N  N   . VAL D 4 37  ? 135.509 135.594 155.672 1.00 62.28  ? 37  VAL E N   1 
ATOM   4702 C  CA  . VAL D 4 37  ? 134.249 135.747 156.393 1.00 62.28  ? 37  VAL E CA  1 
ATOM   4703 C  C   . VAL D 4 37  ? 134.473 136.751 157.515 1.00 62.28  ? 37  VAL E C   1 
ATOM   4704 O  O   . VAL D 4 37  ? 135.417 136.605 158.298 1.00 62.28  ? 37  VAL E O   1 
ATOM   4705 C  CB  . VAL D 4 37  ? 133.734 134.409 156.952 1.00 62.28  ? 37  VAL E CB  1 
ATOM   4706 C  CG1 . VAL D 4 37  ? 132.457 134.623 157.743 1.00 62.28  ? 37  VAL E CG1 1 
ATOM   4707 C  CG2 . VAL D 4 37  ? 133.501 133.412 155.826 1.00 62.28  ? 37  VAL E CG2 1 
ATOM   4708 N  N   . ARG D 4 38  ? 133.617 137.763 157.597 1.00 67.27  ? 38  ARG E N   1 
ATOM   4709 C  CA  . ARG D 4 38  ? 133.787 138.808 158.596 1.00 67.27  ? 38  ARG E CA  1 
ATOM   4710 C  C   . ARG D 4 38  ? 132.719 138.705 159.676 1.00 67.27  ? 38  ARG E C   1 
ATOM   4711 O  O   . ARG D 4 38  ? 131.653 138.119 159.475 1.00 67.27  ? 38  ARG E O   1 
ATOM   4712 C  CB  . ARG D 4 38  ? 133.742 140.201 157.965 1.00 67.27  ? 38  ARG E CB  1 
ATOM   4713 C  CG  . ARG D 4 38  ? 132.359 140.672 157.558 1.00 67.27  ? 38  ARG E CG  1 
ATOM   4714 C  CD  . ARG D 4 38  ? 132.415 142.087 157.006 1.00 67.27  ? 38  ARG E CD  1 
ATOM   4715 N  NE  . ARG D 4 38  ? 131.103 142.570 156.597 1.00 67.27  ? 38  ARG E NE  1 
ATOM   4716 C  CZ  . ARG D 4 38  ? 130.881 143.758 156.052 1.00 67.27  ? 38  ARG E CZ  1 
ATOM   4717 N  NH1 . ARG D 4 38  ? 131.867 144.611 155.829 1.00 67.27  ? 38  ARG E NH1 1 
ATOM   4718 N  NH2 . ARG D 4 38  ? 129.639 144.097 155.719 1.00 67.27  ? 38  ARG E NH2 1 
ATOM   4719 N  N   . GLN D 4 39  ? 133.026 139.291 160.831 1.00 67.40  ? 39  GLN E N   1 
ATOM   4720 C  CA  . GLN D 4 39  ? 132.143 139.256 161.991 1.00 67.40  ? 39  GLN E CA  1 
ATOM   4721 C  C   . GLN D 4 39  ? 132.350 140.530 162.791 1.00 67.40  ? 39  GLN E C   1 
ATOM   4722 O  O   . GLN D 4 39  ? 133.472 140.819 163.213 1.00 67.40  ? 39  GLN E O   1 
ATOM   4723 C  CB  . GLN D 4 39  ? 132.431 138.027 162.859 1.00 67.40  ? 39  GLN E CB  1 
ATOM   4724 C  CG  . GLN D 4 39  ? 131.772 138.051 164.222 1.00 67.40  ? 39  GLN E CG  1 
ATOM   4725 C  CD  . GLN D 4 39  ? 132.427 137.097 165.201 1.00 67.40  ? 39  GLN E CD  1 
ATOM   4726 O  OE1 . GLN D 4 39  ? 133.622 136.819 165.108 1.00 67.40  ? 39  GLN E OE1 1 
ATOM   4727 N  NE2 . GLN D 4 39  ? 131.645 136.592 166.148 1.00 67.40  ? 39  GLN E NE2 1 
ATOM   4728 N  N   . VAL D 4 40  ? 131.286 141.297 162.985 1.00 67.98  ? 40  VAL E N   1 
ATOM   4729 C  CA  . VAL D 4 40  ? 131.403 142.488 163.834 1.00 67.98  ? 40  VAL E CA  1 
ATOM   4730 C  C   . VAL D 4 40  ? 131.619 142.048 165.276 1.00 67.98  ? 40  VAL E C   1 
ATOM   4731 O  O   . VAL D 4 40  ? 131.166 140.953 165.658 1.00 67.98  ? 40  VAL E O   1 
ATOM   4732 C  CB  . VAL D 4 40  ? 130.158 143.365 163.699 1.00 67.98  ? 40  VAL E CB  1 
ATOM   4733 C  CG1 . VAL D 4 40  ? 130.085 143.961 162.301 1.00 67.98  ? 40  VAL E CG1 1 
ATOM   4734 C  CG2 . VAL D 4 40  ? 128.912 142.558 163.994 1.00 67.98  ? 40  VAL E CG2 1 
ATOM   4735 N  N   . PRO D 4 41  ? 132.304 142.839 166.107 1.00 68.32  ? 41  PRO E N   1 
ATOM   4736 C  CA  . PRO D 4 41  ? 132.619 142.378 167.471 1.00 68.32  ? 41  PRO E CA  1 
ATOM   4737 C  C   . PRO D 4 41  ? 131.402 142.164 168.358 1.00 68.32  ? 41  PRO E C   1 
ATOM   4738 O  O   . PRO D 4 41  ? 131.576 141.808 169.531 1.00 68.32  ? 41  PRO E O   1 
ATOM   4739 C  CB  . PRO D 4 41  ? 133.513 143.499 168.021 1.00 68.32  ? 41  PRO E CB  1 
ATOM   4740 C  CG  . PRO D 4 41  ? 134.090 144.150 166.808 1.00 68.32  ? 41  PRO E CG  1 
ATOM   4741 C  CD  . PRO D 4 41  ? 133.001 144.093 165.777 1.00 68.32  ? 41  PRO E CD  1 
ATOM   4742 N  N   . GLY D 4 42  ? 130.188 142.363 167.851 1.00 68.17  ? 42  GLY E N   1 
ATOM   4743 C  CA  . GLY D 4 42  ? 129.000 142.162 168.655 1.00 68.17  ? 42  GLY E CA  1 
ATOM   4744 C  C   . GLY D 4 42  ? 128.080 141.068 168.151 1.00 68.17  ? 42  GLY E C   1 
ATOM   4745 O  O   . GLY D 4 42  ? 127.388 140.422 168.943 1.00 68.17  ? 42  GLY E O   1 
ATOM   4746 N  N   . LYS D 4 43  ? 128.063 140.846 166.837 1.00 67.35  ? 43  LYS E N   1 
ATOM   4747 C  CA  . LYS D 4 43  ? 127.131 139.895 166.243 1.00 67.35  ? 43  LYS E CA  1 
ATOM   4748 C  C   . LYS D 4 43  ? 127.867 138.752 165.555 1.00 67.35  ? 43  LYS E C   1 
ATOM   4749 O  O   . LYS D 4 43  ? 129.084 138.611 165.706 1.00 67.35  ? 43  LYS E O   1 
ATOM   4750 C  CB  . LYS D 4 43  ? 126.198 140.602 165.256 1.00 67.35  ? 43  LYS E CB  1 
ATOM   4751 C  CG  . LYS D 4 43  ? 125.759 141.987 165.706 1.00 67.35  ? 43  LYS E CG  1 
ATOM   4752 C  CD  . LYS D 4 43  ? 124.616 141.911 166.704 1.00 67.35  ? 43  LYS E CD  1 
ATOM   4753 C  CE  . LYS D 4 43  ? 124.399 143.249 167.395 1.00 67.35  ? 43  LYS E CE  1 
ATOM   4754 N  NZ  . LYS D 4 43  ? 123.584 143.111 168.634 1.00 67.35  ? 43  LYS E NZ  1 
ATOM   4755 N  N   . GLY D 4 44  ? 127.137 137.929 164.809 1.00 67.69  ? 44  GLY E N   1 
ATOM   4756 C  CA  . GLY D 4 44  ? 127.693 136.724 164.234 1.00 67.69  ? 44  GLY E CA  1 
ATOM   4757 C  C   . GLY D 4 44  ? 128.495 136.966 162.966 1.00 67.69  ? 44  GLY E C   1 
ATOM   4758 O  O   . GLY D 4 44  ? 128.768 138.093 162.550 1.00 67.69  ? 44  GLY E O   1 
ATOM   4759 N  N   . LEU D 4 45  ? 128.882 135.855 162.342 1.00 64.27  ? 45  LEU E N   1 
ATOM   4760 C  CA  . LEU D 4 45  ? 129.713 135.877 161.148 1.00 64.27  ? 45  LEU E CA  1 
ATOM   4761 C  C   . LEU D 4 45  ? 128.898 136.307 159.930 1.00 64.27  ? 45  LEU E C   1 
ATOM   4762 O  O   . LEU D 4 45  ? 127.680 136.120 159.864 1.00 64.27  ? 45  LEU E O   1 
ATOM   4763 C  CB  . LEU D 4 45  ? 130.324 134.495 160.899 1.00 64.27  ? 45  LEU E CB  1 
ATOM   4764 C  CG  . LEU D 4 45  ? 131.597 134.054 161.636 1.00 64.27  ? 45  LEU E CG  1 
ATOM   4765 C  CD1 . LEU D 4 45  ? 132.792 134.919 161.266 1.00 64.27  ? 45  LEU E CD1 1 
ATOM   4766 C  CD2 . LEU D 4 45  ? 131.397 134.025 163.148 1.00 64.27  ? 45  LEU E CD2 1 
ATOM   4767 N  N   . GLU D 4 46  ? 129.592 136.890 158.951 1.00 65.45  ? 46  GLU E N   1 
ATOM   4768 C  CA  . GLU D 4 46  ? 128.972 137.309 157.697 1.00 65.45  ? 46  GLU E CA  1 
ATOM   4769 C  C   . GLU D 4 46  ? 129.932 137.036 156.550 1.00 65.45  ? 46  GLU E C   1 
ATOM   4770 O  O   . GLU D 4 46  ? 131.113 137.387 156.632 1.00 65.45  ? 46  GLU E O   1 
ATOM   4771 C  CB  . GLU D 4 46  ? 128.591 138.793 157.731 1.00 65.45  ? 46  GLU E CB  1 
ATOM   4772 C  CG  . GLU D 4 46  ? 127.423 139.122 158.647 1.00 65.45  ? 46  GLU E CG  1 
ATOM   4773 C  CD  . GLU D 4 46  ? 126.107 138.567 158.134 1.00 65.45  ? 46  GLU E CD  1 
ATOM   4774 O  OE1 . GLU D 4 46  ? 125.931 138.495 156.900 1.00 65.45  ? 46  GLU E OE1 1 
ATOM   4775 O  OE2 . GLU D 4 46  ? 125.250 138.202 158.966 1.00 65.45  ? 46  GLU E OE2 1 
ATOM   4776 N  N   . PHE D 4 47  ? 129.425 136.417 155.486 1.00 61.03  ? 47  PHE E N   1 
ATOM   4777 C  CA  . PHE D 4 47  ? 130.231 136.161 154.300 1.00 61.03  ? 47  PHE E CA  1 
ATOM   4778 C  C   . PHE D 4 47  ? 130.452 137.448 153.515 1.00 61.03  ? 47  PHE E C   1 
ATOM   4779 O  O   . PHE D 4 47  ? 129.581 138.322 153.470 1.00 61.03  ? 47  PHE E O   1 
ATOM   4780 C  CB  . PHE D 4 47  ? 129.547 135.122 153.412 1.00 61.03  ? 47  PHE E CB  1 
ATOM   4781 C  CG  . PHE D 4 47  ? 130.304 134.802 152.156 1.00 61.03  ? 47  PHE E CG  1 
ATOM   4782 C  CD1 . PHE D 4 47  ? 131.615 134.365 152.213 1.00 61.03  ? 47  PHE E CD1 1 
ATOM   4783 C  CD2 . PHE D 4 47  ? 129.708 134.953 150.916 1.00 61.03  ? 47  PHE E CD2 1 
ATOM   4784 C  CE1 . PHE D 4 47  ? 132.311 134.072 151.058 1.00 61.03  ? 47  PHE E CE1 1 
ATOM   4785 C  CE2 . PHE D 4 47  ? 130.403 134.666 149.758 1.00 61.03  ? 47  PHE E CE2 1 
ATOM   4786 C  CZ  . PHE D 4 47  ? 131.705 134.224 149.830 1.00 61.03  ? 47  PHE E CZ  1 
ATOM   4787 N  N   . VAL D 4 48  ? 131.626 137.569 152.890 1.00 60.97  ? 48  VAL E N   1 
ATOM   4788 C  CA  . VAL D 4 48  ? 131.959 138.718 152.055 1.00 60.97  ? 48  VAL E CA  1 
ATOM   4789 C  C   . VAL D 4 48  ? 132.389 138.300 150.652 1.00 60.97  ? 48  VAL E C   1 
ATOM   4790 O  O   . VAL D 4 48  ? 131.847 138.790 149.656 1.00 60.97  ? 48  VAL E O   1 
ATOM   4791 C  CB  . VAL D 4 48  ? 133.029 139.617 152.721 1.00 60.97  ? 48  VAL E CB  1 
ATOM   4792 C  CG1 . VAL D 4 48  ? 132.459 140.259 153.964 1.00 60.97  ? 48  VAL E CG1 1 
ATOM   4793 C  CG2 . VAL D 4 48  ? 134.274 138.828 153.088 1.00 60.97  ? 48  VAL E CG2 1 
ATOM   4794 N  N   . SER D 4 49  ? 133.354 137.388 150.549 1.00 63.83  ? 49  SER E N   1 
ATOM   4795 C  CA  . SER D 4 49  ? 133.906 137.056 149.240 1.00 63.83  ? 49  SER E CA  1 
ATOM   4796 C  C   . SER D 4 49  ? 134.686 135.752 149.321 1.00 63.83  ? 49  SER E C   1 
ATOM   4797 O  O   . SER D 4 49  ? 135.057 135.291 150.405 1.00 63.83  ? 49  SER E O   1 
ATOM   4798 C  CB  . SER D 4 49  ? 134.802 138.180 148.717 1.00 63.83  ? 49  SER E CB  1 
ATOM   4799 O  OG  . SER D 4 49  ? 135.727 138.594 149.706 1.00 63.83  ? 49  SER E OG  1 
ATOM   4800 N  N   . GLY D 4 50  ? 134.931 135.170 148.152 1.00 63.98  ? 50  GLY E N   1 
ATOM   4801 C  CA  . GLY D 4 50  ? 135.663 133.916 148.058 1.00 63.98  ? 50  GLY E CA  1 
ATOM   4802 C  C   . GLY D 4 50  ? 135.960 133.574 146.615 1.00 63.98  ? 50  GLY E C   1 
ATOM   4803 O  O   . GLY D 4 50  ? 135.471 134.223 145.687 1.00 63.98  ? 50  GLY E O   1 
ATOM   4804 N  N   . LEU D 4 51  ? 136.772 132.532 146.435 1.00 61.95  ? 51  LEU E N   1 
ATOM   4805 C  CA  . LEU D 4 51  ? 137.144 132.111 145.091 1.00 61.95  ? 51  LEU E CA  1 
ATOM   4806 C  C   . LEU D 4 51  ? 137.606 130.661 145.122 1.00 61.95  ? 51  LEU E C   1 
ATOM   4807 O  O   . LEU D 4 51  ? 137.880 130.094 146.187 1.00 61.95  ? 51  LEU E O   1 
ATOM   4808 C  CB  . LEU D 4 51  ? 138.242 132.999 144.497 1.00 61.95  ? 51  LEU E CB  1 
ATOM   4809 C  CG  . LEU D 4 51  ? 139.674 132.844 145.015 1.00 61.95  ? 51  LEU E CG  1 
ATOM   4810 C  CD1 . LEU D 4 51  ? 140.634 133.538 144.063 1.00 61.95  ? 51  LEU E CD1 1 
ATOM   4811 C  CD2 . LEU D 4 51  ? 139.856 133.339 146.435 1.00 61.95  ? 51  LEU E CD2 1 
ATOM   4812 N  N   . ASN D 4 52  ? 137.692 130.075 143.928 1.00 64.90  ? 52  ASN E N   1 
ATOM   4813 C  CA  . ASN D 4 52  ? 138.110 128.694 143.743 1.00 64.90  ? 52  ASN E CA  1 
ATOM   4814 C  C   . ASN D 4 52  ? 139.625 128.631 143.538 1.00 64.90  ? 52  ASN E C   1 
ATOM   4815 O  O   . ASN D 4 52  ? 140.349 129.601 143.779 1.00 64.90  ? 52  ASN E O   1 
ATOM   4816 C  CB  . ASN D 4 52  ? 137.347 128.062 142.580 1.00 64.90  ? 52  ASN E CB  1 
ATOM   4817 C  CG  . ASN D 4 52  ? 137.687 128.694 141.246 1.00 64.90  ? 52  ASN E CG  1 
ATOM   4818 O  OD1 . ASN D 4 52  ? 138.118 129.845 141.182 1.00 64.90  ? 52  ASN E OD1 1 
ATOM   4819 N  ND2 . ASN D 4 52  ? 137.493 127.941 140.169 1.00 64.90  ? 52  ASN E ND2 1 
ATOM   4820 N  N   . TRP D 4 53  A 140.119 127.474 143.089 1.00 66.29  ? 52  TRP E N   1 
ATOM   4821 C  CA  . TRP D 4 53  A 141.560 127.238 143.066 1.00 66.29  ? 52  TRP E CA  1 
ATOM   4822 C  C   . TRP D 4 53  A 142.263 128.085 142.009 1.00 66.29  ? 52  TRP E C   1 
ATOM   4823 O  O   . TRP D 4 53  A 143.346 128.624 142.262 1.00 66.29  ? 52  TRP E O   1 
ATOM   4824 C  CB  . TRP D 4 53  A 141.841 125.750 142.845 1.00 66.29  ? 52  TRP E CB  1 
ATOM   4825 C  CG  . TRP D 4 53  A 141.641 125.283 141.434 1.00 66.29  ? 52  TRP E CG  1 
ATOM   4826 C  CD1 . TRP D 4 53  A 140.457 124.979 140.831 1.00 66.29  ? 52  TRP E CD1 1 
ATOM   4827 C  CD2 . TRP D 4 53  A 142.660 125.063 140.452 1.00 66.29  ? 52  TRP E CD2 1 
ATOM   4828 N  NE1 . TRP D 4 53  A 140.674 124.585 139.533 1.00 66.29  ? 52  TRP E NE1 1 
ATOM   4829 C  CE2 . TRP D 4 53  A 142.019 124.628 139.276 1.00 66.29  ? 52  TRP E CE2 1 
ATOM   4830 C  CE3 . TRP D 4 53  A 144.052 125.192 140.452 1.00 66.29  ? 52  TRP E CE3 1 
ATOM   4831 C  CZ2 . TRP D 4 53  A 142.721 124.323 138.113 1.00 66.29  ? 52  TRP E CZ2 1 
ATOM   4832 C  CZ3 . TRP D 4 53  A 144.747 124.888 139.297 1.00 66.29  ? 52  TRP E CZ3 1 
ATOM   4833 C  CH2 . TRP D 4 53  A 144.081 124.459 138.143 1.00 66.29  ? 52  TRP E CH2 1 
ATOM   4834 N  N   . ASN D 4 54  ? 141.675 128.212 140.821 1.00 66.08  ? 53  ASN E N   1 
ATOM   4835 C  CA  . ASN D 4 54  ? 142.297 128.949 139.729 1.00 66.08  ? 53  ASN E CA  1 
ATOM   4836 C  C   . ASN D 4 54  ? 141.785 130.377 139.589 1.00 66.08  ? 53  ASN E C   1 
ATOM   4837 O  O   . ASN D 4 54  ? 142.302 131.126 138.754 1.00 66.08  ? 53  ASN E O   1 
ATOM   4838 C  CB  . ASN D 4 54  ? 142.111 128.189 138.407 1.00 66.08  ? 53  ASN E CB  1 
ATOM   4839 C  CG  . ASN D 4 54  ? 140.652 128.057 137.997 1.00 66.08  ? 53  ASN E CG  1 
ATOM   4840 O  OD1 . ASN D 4 54  ? 139.756 128.627 138.620 1.00 66.08  ? 53  ASN E OD1 1 
ATOM   4841 N  ND2 . ASN D 4 54  ? 140.410 127.298 136.934 1.00 66.08  ? 53  ASN E ND2 1 
ATOM   4842 N  N   . GLY D 4 55  ? 140.792 130.773 140.381 1.00 66.06  ? 54  GLY E N   1 
ATOM   4843 C  CA  . GLY D 4 55  ? 140.241 132.107 140.298 1.00 66.06  ? 54  GLY E CA  1 
ATOM   4844 C  C   . GLY D 4 55  ? 139.222 132.317 139.201 1.00 66.06  ? 54  GLY E C   1 
ATOM   4845 O  O   . GLY D 4 55  ? 138.789 133.458 138.995 1.00 66.06  ? 54  GLY E O   1 
ATOM   4846 N  N   . ASP D 4 56  ? 138.830 131.260 138.485 1.00 66.09  ? 55  ASP E N   1 
ATOM   4847 C  CA  . ASP D 4 56  ? 137.840 131.411 137.424 1.00 66.09  ? 55  ASP E CA  1 
ATOM   4848 C  C   . ASP D 4 56  ? 136.488 131.834 137.982 1.00 66.09  ? 55  ASP E C   1 
ATOM   4849 O  O   . ASP D 4 56  ? 135.802 132.676 137.392 1.00 66.09  ? 55  ASP E O   1 
ATOM   4850 C  CB  . ASP D 4 56  ? 137.711 130.108 136.635 1.00 66.09  ? 55  ASP E CB  1 
ATOM   4851 C  CG  . ASP D 4 56  ? 138.801 129.947 135.594 1.00 66.09  ? 55  ASP E CG  1 
ATOM   4852 O  OD1 . ASP D 4 56  ? 139.831 130.646 135.696 1.00 66.09  ? 55  ASP E OD1 1 
ATOM   4853 O  OD2 . ASP D 4 56  ? 138.629 129.120 134.673 1.00 66.09  ? 55  ASP E OD2 1 
ATOM   4854 N  N   . ILE D 4 57  ? 136.088 131.265 139.115 1.00 64.63  ? 56  ILE E N   1 
ATOM   4855 C  CA  . ILE D 4 57  ? 134.816 131.577 139.754 1.00 64.63  ? 56  ILE E CA  1 
ATOM   4856 C  C   . ILE D 4 57  ? 135.106 132.373 141.018 1.00 64.63  ? 56  ILE E C   1 
ATOM   4857 O  O   . ILE D 4 57  ? 135.809 131.893 141.916 1.00 64.63  ? 56  ILE E O   1 
ATOM   4858 C  CB  . ILE D 4 57  ? 134.014 130.307 140.074 1.00 64.63  ? 56  ILE E CB  1 
ATOM   4859 C  CG1 . ILE D 4 57  ? 133.747 129.512 138.795 1.00 64.63  ? 56  ILE E CG1 1 
ATOM   4860 C  CG2 . ILE D 4 57  ? 132.709 130.666 140.763 1.00 64.63  ? 56  ILE E CG2 1 
ATOM   4861 C  CD1 . ILE D 4 57  ? 133.341 128.076 139.042 1.00 64.63  ? 56  ILE E CD1 1 
ATOM   4862 N  N   . THR D 4 58  ? 134.567 133.587 141.087 1.00 65.05  ? 57  THR E N   1 
ATOM   4863 C  CA  . THR D 4 58  ? 134.736 134.468 142.233 1.00 65.05  ? 57  THR E CA  1 
ATOM   4864 C  C   . THR D 4 58  ? 133.365 134.897 142.733 1.00 65.05  ? 57  THR E C   1 
ATOM   4865 O  O   . THR D 4 58  ? 132.473 135.193 141.931 1.00 65.05  ? 57  THR E O   1 
ATOM   4866 C  CB  . THR D 4 58  ? 135.575 135.698 141.874 1.00 65.05  ? 57  THR E CB  1 
ATOM   4867 O  OG1 . THR D 4 58  ? 134.911 136.450 140.850 1.00 65.05  ? 57  THR E OG1 1 
ATOM   4868 C  CG2 . THR D 4 58  ? 136.952 135.281 141.378 1.00 65.05  ? 57  THR E CG2 1 
ATOM   4869 N  N   . ALA D 4 59  ? 133.199 134.926 144.051 1.00 61.57  ? 58  ALA E N   1 
ATOM   4870 C  CA  . ALA D 4 59  ? 131.940 135.290 144.683 1.00 61.57  ? 58  ALA E CA  1 
ATOM   4871 C  C   . ALA D 4 59  ? 132.141 136.515 145.560 1.00 61.57  ? 58  ALA E C   1 
ATOM   4872 O  O   . ALA D 4 59  ? 133.056 136.544 146.391 1.00 61.57  ? 58  ALA E O   1 
ATOM   4873 C  CB  . ALA D 4 59  ? 131.394 134.134 145.522 1.00 61.57  ? 58  ALA E CB  1 
ATOM   4874 N  N   . TYR D 4 60  ? 131.289 137.520 145.367 1.00 61.39  ? 59  TYR E N   1 
ATOM   4875 C  CA  . TYR D 4 60  ? 131.205 138.678 146.241 1.00 61.39  ? 59  TYR E CA  1 
ATOM   4876 C  C   . TYR D 4 60  ? 129.765 138.831 146.705 1.00 61.39  ? 59  TYR E C   1 
ATOM   4877 O  O   . TYR D 4 60  ? 128.825 138.548 145.956 1.00 61.39  ? 59  TYR E O   1 
ATOM   4878 C  CB  . TYR D 4 60  ? 131.656 139.967 145.540 1.00 61.39  ? 59  TYR E CB  1 
ATOM   4879 C  CG  . TYR D 4 60  ? 133.109 139.993 145.130 1.00 61.39  ? 59  TYR E CG  1 
ATOM   4880 C  CD1 . TYR D 4 60  ? 133.499 139.587 143.863 1.00 61.39  ? 59  TYR E CD1 1 
ATOM   4881 C  CD2 . TYR D 4 60  ? 134.088 140.441 146.003 1.00 61.39  ? 59  TYR E CD2 1 
ATOM   4882 C  CE1 . TYR D 4 60  ? 134.824 139.616 143.480 1.00 61.39  ? 59  TYR E CE1 1 
ATOM   4883 C  CE2 . TYR D 4 60  ? 135.417 140.473 145.629 1.00 61.39  ? 59  TYR E CE2 1 
ATOM   4884 C  CZ  . TYR D 4 60  ? 135.779 140.060 144.366 1.00 61.39  ? 59  TYR E CZ  1 
ATOM   4885 O  OH  . TYR D 4 60  ? 137.100 140.090 143.989 1.00 61.39  ? 59  TYR E OH  1 
ATOM   4886 N  N   . THR D 4 61  ? 129.592 139.280 147.944 1.00 61.41  ? 60  THR E N   1 
ATOM   4887 C  CA  . THR D 4 61  ? 128.244 139.465 148.454 1.00 61.41  ? 60  THR E CA  1 
ATOM   4888 C  C   . THR D 4 61  ? 127.647 140.761 147.908 1.00 61.41  ? 60  THR E C   1 
ATOM   4889 O  O   . THR D 4 61  ? 128.295 141.524 147.186 1.00 61.41  ? 60  THR E O   1 
ATOM   4890 C  CB  . THR D 4 61  ? 128.235 139.463 149.983 1.00 61.41  ? 60  THR E CB  1 
ATOM   4891 O  OG1 . THR D 4 61  ? 126.888 139.334 150.452 1.00 61.41  ? 60  THR E OG1 1 
ATOM   4892 C  CG2 . THR D 4 61  ? 128.816 140.752 150.525 1.00 61.41  ? 60  THR E CG2 1 
ATOM   4893 N  N   . ASP D 4 62  ? 126.382 141.001 148.258 1.00 63.82  ? 61  ASP E N   1 
ATOM   4894 C  CA  . ASP D 4 62  ? 125.669 142.155 147.719 1.00 63.82  ? 61  ASP E CA  1 
ATOM   4895 C  C   . ASP D 4 62  ? 126.287 143.469 148.185 1.00 63.82  ? 61  ASP E C   1 
ATOM   4896 O  O   . ASP D 4 62  ? 126.392 144.424 147.406 1.00 63.82  ? 61  ASP E O   1 
ATOM   4897 C  CB  . ASP D 4 62  ? 124.194 142.088 148.113 1.00 63.82  ? 61  ASP E CB  1 
ATOM   4898 C  CG  . ASP D 4 62  ? 123.466 140.939 147.446 1.00 63.82  ? 61  ASP E CG  1 
ATOM   4899 O  OD1 . ASP D 4 62  ? 124.142 140.024 146.932 1.00 63.82  ? 61  ASP E OD1 1 
ATOM   4900 O  OD2 . ASP D 4 62  ? 122.217 140.951 147.435 1.00 63.82  ? 61  ASP E OD2 1 
ATOM   4901 N  N   . SER D 4 63  ? 126.700 143.539 149.450 1.00 64.98  ? 62  SER E N   1 
ATOM   4902 C  CA  . SER D 4 63  ? 127.146 144.798 150.033 1.00 64.98  ? 62  SER E CA  1 
ATOM   4903 C  C   . SER D 4 63  ? 128.585 145.159 149.685 1.00 64.98  ? 62  SER E C   1 
ATOM   4904 O  O   . SER D 4 63  ? 129.005 146.283 149.979 1.00 64.98  ? 62  SER E O   1 
ATOM   4905 C  CB  . SER D 4 63  ? 126.989 144.752 151.555 1.00 64.98  ? 62  SER E CB  1 
ATOM   4906 O  OG  . SER D 4 63  ? 127.873 143.806 152.131 1.00 64.98  ? 62  SER E OG  1 
ATOM   4907 N  N   . VAL D 4 64  ? 129.350 144.253 149.077 1.00 64.92  ? 63  VAL E N   1 
ATOM   4908 C  CA  . VAL D 4 64  ? 130.747 144.534 148.758 1.00 64.92  ? 63  VAL E CA  1 
ATOM   4909 C  C   . VAL D 4 64  ? 131.009 144.266 147.281 1.00 64.92  ? 63  VAL E C   1 
ATOM   4910 O  O   . VAL D 4 64  ? 132.164 144.142 146.857 1.00 64.92  ? 63  VAL E O   1 
ATOM   4911 C  CB  . VAL D 4 64  ? 131.702 143.710 149.645 1.00 64.92  ? 63  VAL E CB  1 
ATOM   4912 C  CG1 . VAL D 4 64  ? 131.331 143.849 151.115 1.00 64.92  ? 63  VAL E CG1 1 
ATOM   4913 C  CG2 . VAL D 4 64  ? 131.711 142.247 149.225 1.00 64.92  ? 63  VAL E CG2 1 
ATOM   4914 N  N   . LYS D 4 65  ? 129.938 144.199 146.486 1.00 67.07  ? 64  LYS E N   1 
ATOM   4915 C  CA  . LYS D 4 65  ? 130.076 143.804 145.087 1.00 67.07  ? 64  LYS E CA  1 
ATOM   4916 C  C   . LYS D 4 65  ? 130.944 144.783 144.305 1.00 67.07  ? 64  LYS E C   1 
ATOM   4917 O  O   . LYS D 4 65  ? 131.796 144.369 143.510 1.00 67.07  ? 64  LYS E O   1 
ATOM   4918 C  CB  . LYS D 4 65  ? 128.698 143.680 144.439 1.00 67.07  ? 64  LYS E CB  1 
ATOM   4919 C  CG  . LYS D 4 65  ? 128.700 142.922 143.123 1.00 67.07  ? 64  LYS E CG  1 
ATOM   4920 C  CD  . LYS D 4 65  ? 127.287 142.702 142.610 1.00 67.07  ? 64  LYS E CD  1 
ATOM   4921 C  CE  . LYS D 4 65  ? 126.556 141.661 143.440 1.00 67.07  ? 64  LYS E CE  1 
ATOM   4922 N  NZ  . LYS D 4 65  ? 127.153 140.307 143.282 1.00 67.07  ? 64  LYS E NZ  1 
ATOM   4923 N  N   . GLY D 4 66  ? 130.746 146.079 144.514 1.00 67.49  ? 65  GLY E N   1 
ATOM   4924 C  CA  . GLY D 4 66  ? 131.439 147.079 143.734 1.00 67.49  ? 65  GLY E CA  1 
ATOM   4925 C  C   . GLY D 4 66  ? 132.676 147.683 144.355 1.00 67.49  ? 65  GLY E C   1 
ATOM   4926 O  O   . GLY D 4 66  ? 133.240 148.621 143.783 1.00 67.49  ? 65  GLY E O   1 
ATOM   4927 N  N   . ARG D 4 67  ? 133.127 147.184 145.508 1.00 70.27  ? 66  ARG E N   1 
ATOM   4928 C  CA  . ARG D 4 67  ? 134.266 147.797 146.179 1.00 70.27  ? 66  ARG E CA  1 
ATOM   4929 C  C   . ARG D 4 67  ? 135.234 146.786 146.783 1.00 70.27  ? 66  ARG E C   1 
ATOM   4930 O  O   . ARG D 4 67  ? 136.068 147.175 147.611 1.00 70.27  ? 66  ARG E O   1 
ATOM   4931 C  CB  . ARG D 4 67  ? 133.778 148.756 147.270 1.00 70.27  ? 66  ARG E CB  1 
ATOM   4932 C  CG  . ARG D 4 67  ? 132.495 148.314 147.945 1.00 70.27  ? 66  ARG E CG  1 
ATOM   4933 C  CD  . ARG D 4 67  ? 131.860 149.446 148.731 1.00 70.27  ? 66  ARG E CD  1 
ATOM   4934 N  NE  . ARG D 4 67  ? 130.679 148.997 149.457 1.00 70.27  ? 66  ARG E NE  1 
ATOM   4935 C  CZ  . ARG D 4 67  ? 130.625 148.839 150.772 1.00 70.27  ? 66  ARG E CZ  1 
ATOM   4936 N  NH1 . ARG D 4 67  ? 131.667 149.102 151.543 1.00 70.27  ? 66  ARG E NH1 1 
ATOM   4937 N  NH2 . ARG D 4 67  ? 129.498 148.404 151.327 1.00 70.27  ? 66  ARG E NH2 1 
ATOM   4938 N  N   . PHE D 4 68  ? 135.162 145.514 146.401 1.00 69.94  ? 67  PHE E N   1 
ATOM   4939 C  CA  . PHE D 4 68  ? 136.026 144.476 146.947 1.00 69.94  ? 67  PHE E CA  1 
ATOM   4940 C  C   . PHE D 4 68  ? 136.775 143.776 145.822 1.00 69.94  ? 67  PHE E C   1 
ATOM   4941 O  O   . PHE D 4 68  ? 136.213 143.525 144.751 1.00 69.94  ? 67  PHE E O   1 
ATOM   4942 C  CB  . PHE D 4 68  ? 135.220 143.452 147.753 1.00 69.94  ? 67  PHE E CB  1 
ATOM   4943 C  CG  . PHE D 4 68  ? 135.124 143.769 149.219 1.00 69.94  ? 67  PHE E CG  1 
ATOM   4944 C  CD1 . PHE D 4 68  ? 134.934 145.070 149.651 1.00 69.94  ? 67  PHE E CD1 1 
ATOM   4945 C  CD2 . PHE D 4 68  ? 135.218 142.763 150.165 1.00 69.94  ? 67  PHE E CD2 1 
ATOM   4946 C  CE1 . PHE D 4 68  ? 134.843 145.363 150.998 1.00 69.94  ? 67  PHE E CE1 1 
ATOM   4947 C  CE2 . PHE D 4 68  ? 135.128 143.050 151.514 1.00 69.94  ? 67  PHE E CE2 1 
ATOM   4948 C  CZ  . PHE D 4 68  ? 134.941 144.352 151.930 1.00 69.94  ? 67  PHE E CZ  1 
ATOM   4949 N  N   . THR D 4 69  ? 138.044 143.461 146.072 1.00 70.63  ? 68  THR E N   1 
ATOM   4950 C  CA  . THR D 4 69  ? 138.882 142.736 145.126 1.00 70.63  ? 68  THR E CA  1 
ATOM   4951 C  C   . THR D 4 69  ? 139.432 141.499 145.819 1.00 70.63  ? 68  THR E C   1 
ATOM   4952 O  O   . THR D 4 69  ? 139.911 141.587 146.952 1.00 70.63  ? 68  THR E O   1 
ATOM   4953 C  CB  . THR D 4 69  ? 140.028 143.615 144.610 1.00 70.63  ? 68  THR E CB  1 
ATOM   4954 O  OG1 . THR D 4 69  ? 139.499 144.642 143.760 1.00 70.63  ? 68  THR E OG1 1 
ATOM   4955 C  CG2 . THR D 4 69  ? 141.035 142.786 143.827 1.00 70.63  ? 68  THR E CG2 1 
ATOM   4956 N  N   . VAL D 4 70  ? 139.352 140.350 145.156 1.00 66.20  ? 69  VAL E N   1 
ATOM   4957 C  CA  . VAL D 4 70  ? 139.819 139.089 145.717 1.00 66.20  ? 69  VAL E CA  1 
ATOM   4958 C  C   . VAL D 4 70  ? 140.781 138.443 144.730 1.00 66.20  ? 69  VAL E C   1 
ATOM   4959 O  O   . VAL D 4 70  ? 140.453 138.292 143.547 1.00 66.20  ? 69  VAL E O   1 
ATOM   4960 C  CB  . VAL D 4 70  ? 138.646 138.149 146.042 1.00 66.20  ? 69  VAL E CB  1 
ATOM   4961 C  CG1 . VAL D 4 70  ? 139.119 136.721 146.113 1.00 66.20  ? 69  VAL E CG1 1 
ATOM   4962 C  CG2 . VAL D 4 70  ? 138.013 138.557 147.352 1.00 66.20  ? 69  VAL E CG2 1 
ATOM   4963 N  N   . SER D 4 71  ? 141.963 138.066 145.213 1.00 66.19  ? 70  SER E N   1 
ATOM   4964 C  CA  . SER D 4 71  ? 142.950 137.427 144.357 1.00 66.19  ? 70  SER E CA  1 
ATOM   4965 C  C   . SER D 4 71  ? 143.724 136.399 145.165 1.00 66.19  ? 70  SER E C   1 
ATOM   4966 O  O   . SER D 4 71  ? 143.751 136.440 146.396 1.00 66.19  ? 70  SER E O   1 
ATOM   4967 C  CB  . SER D 4 71  ? 143.907 138.452 143.737 1.00 66.19  ? 70  SER E CB  1 
ATOM   4968 O  OG  . SER D 4 71  ? 144.936 137.811 143.003 1.00 66.19  ? 70  SER E OG  1 
ATOM   4969 N  N   . ARG D 4 72  ? 144.348 135.461 144.458 1.00 63.94  ? 71  ARG E N   1 
ATOM   4970 C  CA  . ARG D 4 72  ? 145.222 134.489 145.093 1.00 63.94  ? 71  ARG E CA  1 
ATOM   4971 C  C   . ARG D 4 72  ? 146.485 134.331 144.262 1.00 63.94  ? 71  ARG E C   1 
ATOM   4972 O  O   . ARG D 4 72  ? 146.451 134.398 143.030 1.00 63.94  ? 71  ARG E O   1 
ATOM   4973 C  CB  . ARG D 4 72  ? 144.536 133.128 145.280 1.00 63.94  ? 71  ARG E CB  1 
ATOM   4974 C  CG  . ARG D 4 72  ? 144.177 132.413 143.993 1.00 63.94  ? 71  ARG E CG  1 
ATOM   4975 C  CD  . ARG D 4 72  ? 143.299 131.208 144.275 1.00 63.94  ? 71  ARG E CD  1 
ATOM   4976 N  NE  . ARG D 4 72  ? 143.964 130.243 145.140 1.00 63.94  ? 71  ARG E NE  1 
ATOM   4977 C  CZ  . ARG D 4 72  ? 143.337 129.307 145.838 1.00 63.94  ? 71  ARG E CZ  1 
ATOM   4978 N  NH1 . ARG D 4 72  ? 142.021 129.181 145.799 1.00 63.94  ? 71  ARG E NH1 1 
ATOM   4979 N  NH2 . ARG D 4 72  ? 144.048 128.477 146.596 1.00 63.94  ? 71  ARG E NH2 1 
ATOM   4980 N  N   . ASP D 4 73  ? 147.604 134.131 144.951 1.00 70.00  ? 72  ASP E N   1 
ATOM   4981 C  CA  . ASP D 4 73  ? 148.901 133.903 144.320 1.00 70.00  ? 72  ASP E CA  1 
ATOM   4982 C  C   . ASP D 4 73  ? 149.394 132.537 144.783 1.00 70.00  ? 72  ASP E C   1 
ATOM   4983 O  O   . ASP D 4 73  ? 149.916 132.400 145.895 1.00 70.00  ? 72  ASP E O   1 
ATOM   4984 C  CB  . ASP D 4 73  ? 149.890 135.011 144.671 1.00 70.00  ? 72  ASP E CB  1 
ATOM   4985 C  CG  . ASP D 4 73  ? 151.007 135.138 143.654 1.00 70.00  ? 72  ASP E CG  1 
ATOM   4986 O  OD1 . ASP D 4 73  ? 151.374 134.115 143.038 1.00 70.00  ? 72  ASP E OD1 1 
ATOM   4987 O  OD2 . ASP D 4 73  ? 151.517 136.263 143.465 1.00 70.00  ? 72  ASP E OD2 1 
ATOM   4988 N  N   . ASN D 4 74  ? 149.213 131.526 143.932 1.00 68.83  ? 73  ASN E N   1 
ATOM   4989 C  CA  . ASN D 4 74  ? 149.634 130.174 144.273 1.00 68.83  ? 73  ASN E CA  1 
ATOM   4990 C  C   . ASN D 4 74  ? 151.148 130.027 144.287 1.00 68.83  ? 73  ASN E C   1 
ATOM   4991 O  O   . ASN D 4 74  ? 151.666 129.156 144.994 1.00 68.83  ? 73  ASN E O   1 
ATOM   4992 C  CB  . ASN D 4 74  ? 149.020 129.174 143.293 1.00 68.83  ? 73  ASN E CB  1 
ATOM   4993 C  CG  . ASN D 4 74  ? 147.514 129.079 143.427 1.00 68.83  ? 73  ASN E CG  1 
ATOM   4994 O  OD1 . ASN D 4 74  ? 146.981 129.016 144.533 1.00 68.83  ? 73  ASN E OD1 1 
ATOM   4995 N  ND2 . ASN D 4 74  ? 146.819 129.072 142.297 1.00 68.83  ? 73  ASN E ND2 1 
ATOM   4996 N  N   . ALA D 4 75  ? 151.868 130.847 143.517 1.00 72.55  ? 74  ALA E N   1 
ATOM   4997 C  CA  . ALA D 4 75  ? 153.326 130.793 143.543 1.00 72.55  ? 74  ALA E CA  1 
ATOM   4998 C  C   . ALA D 4 75  ? 153.864 131.167 144.918 1.00 72.55  ? 74  ALA E C   1 
ATOM   4999 O  O   . ALA D 4 75  ? 154.794 130.530 145.424 1.00 72.55  ? 74  ALA E O   1 
ATOM   5000 C  CB  . ALA D 4 75  ? 153.906 131.712 142.469 1.00 72.55  ? 74  ALA E CB  1 
ATOM   5001 N  N   . LYS D 4 76  ? 153.292 132.199 145.536 1.00 72.46  ? 75  LYS E N   1 
ATOM   5002 C  CA  . LYS D 4 76  ? 153.651 132.580 146.893 1.00 72.46  ? 75  LYS E CA  1 
ATOM   5003 C  C   . LYS D 4 76  ? 152.759 131.935 147.944 1.00 72.46  ? 75  LYS E C   1 
ATOM   5004 O  O   . LYS D 4 76  ? 153.006 132.126 149.140 1.00 72.46  ? 75  LYS E O   1 
ATOM   5005 C  CB  . LYS D 4 76  ? 153.595 134.103 147.052 1.00 72.46  ? 75  LYS E CB  1 
ATOM   5006 C  CG  . LYS D 4 76  ? 154.642 134.855 146.249 1.00 72.46  ? 75  LYS E CG  1 
ATOM   5007 C  CD  . LYS D 4 76  ? 154.629 136.337 146.586 1.00 72.46  ? 75  LYS E CD  1 
ATOM   5008 C  CE  . LYS D 4 76  ? 153.419 137.031 145.982 1.00 72.46  ? 75  LYS E CE  1 
ATOM   5009 N  NZ  . LYS D 4 76  ? 153.450 138.502 146.211 1.00 72.46  ? 75  LYS E NZ  1 
ATOM   5010 N  N   . ASN D 4 77  ? 151.743 131.181 147.528 1.00 70.94  ? 76  ASN E N   1 
ATOM   5011 C  CA  . ASN D 4 77  ? 150.794 130.538 148.436 1.00 70.94  ? 76  ASN E CA  1 
ATOM   5012 C  C   . ASN D 4 77  ? 150.157 131.567 149.370 1.00 70.94  ? 76  ASN E C   1 
ATOM   5013 O  O   . ASN D 4 77  ? 150.310 131.522 150.592 1.00 70.94  ? 76  ASN E O   1 
ATOM   5014 C  CB  . ASN D 4 77  ? 151.469 129.416 149.229 1.00 70.94  ? 76  ASN E CB  1 
ATOM   5015 C  CG  . ASN D 4 77  ? 151.250 128.051 148.609 1.00 70.94  ? 76  ASN E CG  1 
ATOM   5016 O  OD1 . ASN D 4 77  ? 150.899 127.939 147.435 1.00 70.94  ? 76  ASN E OD1 1 
ATOM   5017 N  ND2 . ASN D 4 77  ? 151.456 127.003 149.398 1.00 70.94  ? 76  ASN E ND2 1 
ATOM   5018 N  N   . SER D 4 78  ? 149.429 132.506 148.770 1.00 69.50  ? 77  SER E N   1 
ATOM   5019 C  CA  . SER D 4 78  ? 148.841 133.600 149.526 1.00 69.50  ? 77  SER E CA  1 
ATOM   5020 C  C   . SER D 4 78  ? 147.479 133.971 148.959 1.00 69.50  ? 77  SER E C   1 
ATOM   5021 O  O   . SER D 4 78  ? 147.185 133.733 147.785 1.00 69.50  ? 77  SER E O   1 
ATOM   5022 C  CB  . SER D 4 78  ? 149.756 134.832 149.527 1.00 69.50  ? 77  SER E CB  1 
ATOM   5023 O  OG  . SER D 4 78  ? 150.281 135.078 148.234 1.00 69.50  ? 77  SER E OG  1 
ATOM   5024 N  N   . LEU D 4 79  ? 146.654 134.565 149.819 1.00 67.82  ? 78  LEU E N   1 
ATOM   5025 C  CA  . LEU D 4 79  ? 145.336 135.074 149.465 1.00 67.82  ? 78  LEU E CA  1 
ATOM   5026 C  C   . LEU D 4 79  ? 145.285 136.552 149.822 1.00 67.82  ? 78  LEU E C   1 
ATOM   5027 O  O   . LEU D 4 79  ? 145.726 136.941 150.905 1.00 67.82  ? 78  LEU E O   1 
ATOM   5028 C  CB  . LEU D 4 79  ? 144.238 134.303 150.206 1.00 67.82  ? 78  LEU E CB  1 
ATOM   5029 C  CG  . LEU D 4 79  ? 142.790 134.760 150.047 1.00 67.82  ? 78  LEU E CG  1 
ATOM   5030 C  CD1 . LEU D 4 79  ? 142.359 134.653 148.606 1.00 67.82  ? 78  LEU E CD1 1 
ATOM   5031 C  CD2 . LEU D 4 79  ? 141.879 133.936 150.938 1.00 67.82  ? 78  LEU E CD2 1 
ATOM   5032 N  N   . TYR D 4 80  ? 144.762 137.377 148.919 1.00 69.88  ? 79  TYR E N   1 
ATOM   5033 C  CA  . TYR D 4 80  ? 144.727 138.818 149.119 1.00 69.88  ? 79  TYR E CA  1 
ATOM   5034 C  C   . TYR D 4 80  ? 143.318 139.353 148.914 1.00 69.88  ? 79  TYR E C   1 
ATOM   5035 O  O   . TYR D 4 80  ? 142.653 139.034 147.919 1.00 69.88  ? 79  TYR E O   1 
ATOM   5036 C  CB  . TYR D 4 80  ? 145.697 139.526 148.173 1.00 69.88  ? 79  TYR E CB  1 
ATOM   5037 C  CG  . TYR D 4 80  ? 147.121 139.039 148.290 1.00 69.88  ? 79  TYR E CG  1 
ATOM   5038 C  CD1 . TYR D 4 80  ? 147.841 139.221 149.462 1.00 69.88  ? 79  TYR E CD1 1 
ATOM   5039 C  CD2 . TYR D 4 80  ? 147.746 138.400 147.229 1.00 69.88  ? 79  TYR E CD2 1 
ATOM   5040 C  CE1 . TYR D 4 80  ? 149.145 138.779 149.576 1.00 69.88  ? 79  TYR E CE1 1 
ATOM   5041 C  CE2 . TYR D 4 80  ? 149.050 137.954 147.333 1.00 69.88  ? 79  TYR E CE2 1 
ATOM   5042 C  CZ  . TYR D 4 80  ? 149.744 138.146 148.508 1.00 69.88  ? 79  TYR E CZ  1 
ATOM   5043 O  OH  . TYR D 4 80  ? 151.043 137.703 148.616 1.00 69.88  ? 79  TYR E OH  1 
ATOM   5044 N  N   . LEU D 4 81  ? 142.874 140.172 149.865 1.00 71.12  ? 80  LEU E N   1 
ATOM   5045 C  CA  . LEU D 4 81  ? 141.593 140.864 149.787 1.00 71.12  ? 80  LEU E CA  1 
ATOM   5046 C  C   . LEU D 4 81  ? 141.846 142.363 149.863 1.00 71.12  ? 80  LEU E C   1 
ATOM   5047 O  O   . LEU D 4 81  ? 142.401 142.853 150.851 1.00 71.12  ? 80  LEU E O   1 
ATOM   5048 C  CB  . LEU D 4 81  ? 140.653 140.419 150.908 1.00 71.12  ? 80  LEU E CB  1 
ATOM   5049 C  CG  . LEU D 4 81  ? 139.433 141.307 151.155 1.00 71.12  ? 80  LEU E CG  1 
ATOM   5050 C  CD1 . LEU D 4 81  ? 138.452 141.203 150.001 1.00 71.12  ? 80  LEU E CD1 1 
ATOM   5051 C  CD2 . LEU D 4 81  ? 138.759 140.941 152.468 1.00 71.12  ? 80  LEU E CD2 1 
ATOM   5052 N  N   . HIS D 4 82  ? 141.438 143.085 148.826 1.00 74.90  ? 81  HIS E N   1 
ATOM   5053 C  CA  . HIS D 4 82  ? 141.605 144.528 148.740 1.00 74.90  ? 81  HIS E CA  1 
ATOM   5054 C  C   . HIS D 4 82  ? 140.258 145.192 148.989 1.00 74.90  ? 81  HIS E C   1 
ATOM   5055 O  O   . HIS D 4 82  ? 139.280 144.904 148.288 1.00 74.90  ? 81  HIS E O   1 
ATOM   5056 C  CB  . HIS D 4 82  ? 142.163 144.934 147.377 1.00 74.90  ? 81  HIS E CB  1 
ATOM   5057 C  CG  . HIS D 4 82  ? 143.550 144.433 147.122 1.00 74.90  ? 81  HIS E CG  1 
ATOM   5058 N  ND1 . HIS D 4 82  ? 144.092 144.353 145.857 1.00 74.90  ? 81  HIS E ND1 1 
ATOM   5059 C  CD2 . HIS D 4 82  ? 144.505 143.983 147.969 1.00 74.90  ? 81  HIS E CD2 1 
ATOM   5060 C  CE1 . HIS D 4 82  ? 145.321 143.877 145.936 1.00 74.90  ? 81  HIS E CE1 1 
ATOM   5061 N  NE2 . HIS D 4 82  ? 145.596 143.644 147.207 1.00 74.90  ? 81  HIS E NE2 1 
ATOM   5062 N  N   . ILE D 4 83  ? 140.213 146.074 149.982 1.00 75.29  ? 82  ILE E N   1 
ATOM   5063 C  CA  . ILE D 4 83  ? 139.008 146.804 150.350 1.00 75.29  ? 82  ILE E CA  1 
ATOM   5064 C  C   . ILE D 4 83  ? 139.205 148.265 149.977 1.00 75.29  ? 82  ILE E C   1 
ATOM   5065 O  O   . ILE D 4 83  ? 140.129 148.919 150.475 1.00 75.29  ? 82  ILE E O   1 
ATOM   5066 C  CB  . ILE D 4 83  ? 138.690 146.660 151.850 1.00 75.29  ? 82  ILE E CB  1 
ATOM   5067 C  CG1 . ILE D 4 83  ? 138.478 145.189 152.212 1.00 75.29  ? 82  ILE E CG1 1 
ATOM   5068 C  CG2 . ILE D 4 83  ? 137.468 147.487 152.218 1.00 75.29  ? 82  ILE E CG2 1 
ATOM   5069 C  CD1 . ILE D 4 83  ? 138.185 144.957 153.679 1.00 75.29  ? 82  ILE E CD1 1 
ATOM   5070 N  N   . ASN D 4 84  A 138.341 148.768 149.098 1.00 76.57  ? 82  ASN E N   1 
ATOM   5071 C  CA  . ASN D 4 84  A 138.355 150.155 148.661 1.00 76.57  ? 82  ASN E CA  1 
ATOM   5072 C  C   . ASN D 4 84  A 136.994 150.775 148.956 1.00 76.57  ? 82  ASN E C   1 
ATOM   5073 O  O   . ASN D 4 84  A 135.986 150.074 149.085 1.00 76.57  ? 82  ASN E O   1 
ATOM   5074 C  CB  . ASN D 4 84  A 138.698 150.264 147.170 1.00 76.57  ? 82  ASN E CB  1 
ATOM   5075 C  CG  . ASN D 4 84  A 139.972 149.528 146.812 1.00 76.57  ? 82  ASN E CG  1 
ATOM   5076 O  OD1 . ASN D 4 84  A 140.962 149.586 147.540 1.00 76.57  ? 82  ASN E OD1 1 
ATOM   5077 N  ND2 . ASN D 4 84  A 139.953 148.826 145.684 1.00 76.57  ? 82  ASN E ND2 1 
ATOM   5078 N  N   . SER D 4 85  B 136.974 152.100 149.061 1.00 76.15  ? 82  SER E N   1 
ATOM   5079 C  CA  . SER D 4 85  B 135.772 152.855 149.398 1.00 76.15  ? 82  SER E CA  1 
ATOM   5080 C  C   . SER D 4 85  B 135.090 152.308 150.656 1.00 76.15  ? 82  SER E C   1 
ATOM   5081 O  O   . SER D 4 85  B 133.954 151.829 150.594 1.00 76.15  ? 82  SER E O   1 
ATOM   5082 C  CB  . SER D 4 85  B 134.801 152.874 148.225 1.00 76.15  ? 82  SER E CB  1 
ATOM   5083 O  OG  . SER D 4 85  B 135.370 153.523 147.101 1.00 76.15  ? 82  SER E OG  1 
ATOM   5084 N  N   . PRO D 4 86  C 135.757 152.360 151.807 1.00 75.21  ? 82  PRO E N   1 
ATOM   5085 C  CA  . PRO D 4 86  C 135.164 151.797 153.022 1.00 75.21  ? 82  PRO E CA  1 
ATOM   5086 C  C   . PRO D 4 86  C 134.025 152.657 153.544 1.00 75.21  ? 82  PRO E C   1 
ATOM   5087 O  O   . PRO D 4 86  C 133.898 153.838 153.210 1.00 75.21  ? 82  PRO E O   1 
ATOM   5088 C  CB  . PRO D 4 86  C 136.335 151.771 154.014 1.00 75.21  ? 82  PRO E CB  1 
ATOM   5089 C  CG  . PRO D 4 86  C 137.565 152.092 153.200 1.00 75.21  ? 82  PRO E CG  1 
ATOM   5090 C  CD  . PRO D 4 86  C 137.082 152.936 152.075 1.00 75.21  ? 82  PRO E CD  1 
ATOM   5091 N  N   . LYS D 4 87  ? 133.191 152.042 154.373 1.00 76.54  ? 83  LYS E N   1 
ATOM   5092 C  CA  . LYS D 4 87  ? 132.065 152.695 155.019 1.00 76.54  ? 83  LYS E CA  1 
ATOM   5093 C  C   . LYS D 4 87  ? 132.069 152.357 156.501 1.00 76.54  ? 83  LYS E C   1 
ATOM   5094 O  O   . LYS D 4 87  ? 132.642 151.341 156.906 1.00 76.54  ? 83  LYS E O   1 
ATOM   5095 C  CB  . LYS D 4 87  ? 130.733 152.259 154.390 1.00 76.54  ? 83  LYS E CB  1 
ATOM   5096 C  CG  . LYS D 4 87  ? 130.503 152.795 152.988 1.00 76.54  ? 83  LYS E CG  1 
ATOM   5097 C  CD  . LYS D 4 87  ? 129.028 152.776 152.629 1.00 76.54  ? 83  LYS E CD  1 
ATOM   5098 C  CE  . LYS D 4 87  ? 128.524 151.358 152.432 1.00 76.54  ? 83  LYS E CE  1 
ATOM   5099 N  NZ  . LYS D 4 87  ? 127.114 151.331 151.953 1.00 76.54  ? 83  LYS E NZ  1 
ATOM   5100 N  N   . PRO D 4 88  ? 131.442 153.192 157.339 1.00 78.00  ? 84  PRO E N   1 
ATOM   5101 C  CA  . PRO D 4 88  ? 131.396 152.897 158.780 1.00 78.00  ? 84  PRO E CA  1 
ATOM   5102 C  C   . PRO D 4 88  ? 130.692 151.594 159.130 1.00 78.00  ? 84  PRO E C   1 
ATOM   5103 O  O   . PRO D 4 88  ? 130.689 151.212 160.306 1.00 78.00  ? 84  PRO E O   1 
ATOM   5104 C  CB  . PRO D 4 88  ? 130.640 154.105 159.361 1.00 78.00  ? 84  PRO E CB  1 
ATOM   5105 C  CG  . PRO D 4 88  ? 129.921 154.712 158.199 1.00 78.00  ? 84  PRO E CG  1 
ATOM   5106 C  CD  . PRO D 4 88  ? 130.816 154.487 157.025 1.00 78.00  ? 84  PRO E CD  1 
ATOM   5107 N  N   . GLU D 4 89  ? 130.099 150.902 158.160 1.00 78.64  ? 85  GLU E N   1 
ATOM   5108 C  CA  . GLU D 4 89  ? 129.500 149.594 158.381 1.00 78.64  ? 85  GLU E CA  1 
ATOM   5109 C  C   . GLU D 4 89  ? 130.486 148.453 158.172 1.00 78.64  ? 85  GLU E C   1 
ATOM   5110 O  O   . GLU D 4 89  ? 130.084 147.286 158.233 1.00 78.64  ? 85  GLU E O   1 
ATOM   5111 C  CB  . GLU D 4 89  ? 128.293 149.404 157.456 1.00 78.64  ? 85  GLU E CB  1 
ATOM   5112 C  CG  . GLU D 4 89  ? 127.080 150.238 157.836 1.00 78.64  ? 85  GLU E CG  1 
ATOM   5113 C  CD  . GLU D 4 89  ? 126.578 149.933 159.234 1.00 78.64  ? 85  GLU E CD  1 
ATOM   5114 O  OE1 . GLU D 4 89  ? 126.269 148.755 159.512 1.00 78.64  ? 85  GLU E OE1 1 
ATOM   5115 O  OE2 . GLU D 4 89  ? 126.491 150.871 160.053 1.00 78.64  ? 85  GLU E OE2 1 
ATOM   5116 N  N   . ASP D 4 90  ? 131.761 148.757 157.928 1.00 74.76  ? 86  ASP E N   1 
ATOM   5117 C  CA  . ASP D 4 90  ? 132.756 147.730 157.649 1.00 74.76  ? 86  ASP E CA  1 
ATOM   5118 C  C   . ASP D 4 90  ? 133.778 147.629 158.774 1.00 74.76  ? 86  ASP E C   1 
ATOM   5119 O  O   . ASP D 4 90  ? 134.972 147.440 158.521 1.00 74.76  ? 86  ASP E O   1 
ATOM   5120 C  CB  . ASP D 4 90  ? 133.459 148.018 156.322 1.00 74.76  ? 86  ASP E CB  1 
ATOM   5121 C  CG  . ASP D 4 90  ? 132.603 147.672 155.123 1.00 74.76  ? 86  ASP E CG  1 
ATOM   5122 O  OD1 . ASP D 4 90  ? 131.526 147.070 155.315 1.00 74.76  ? 86  ASP E OD1 1 
ATOM   5123 O  OD2 . ASP D 4 90  ? 133.005 148.003 153.988 1.00 74.76  ? 86  ASP E OD2 1 
ATOM   5124 N  N   . THR D 4 91  ? 133.320 147.756 160.016 1.00 75.00  ? 87  THR E N   1 
ATOM   5125 C  CA  . THR D 4 91  ? 134.178 147.587 161.186 1.00 75.00  ? 87  THR E CA  1 
ATOM   5126 C  C   . THR D 4 91  ? 133.934 146.192 161.747 1.00 75.00  ? 87  THR E C   1 
ATOM   5127 O  O   . THR D 4 91  ? 132.903 145.933 162.373 1.00 75.00  ? 87  THR E O   1 
ATOM   5128 C  CB  . THR D 4 91  ? 133.887 148.664 162.226 1.00 75.00  ? 87  THR E CB  1 
ATOM   5129 O  OG1 . THR D 4 91  ? 134.317 149.938 161.731 1.00 75.00  ? 87  THR E OG1 1 
ATOM   5130 C  CG2 . THR D 4 91  ? 134.610 148.361 163.532 1.00 75.00  ? 87  THR E CG2 1 
ATOM   5131 N  N   . ALA D 4 92  ? 134.882 145.283 161.522 1.00 72.40  ? 88  ALA E N   1 
ATOM   5132 C  CA  . ALA D 4 92  ? 134.695 143.896 161.919 1.00 72.40  ? 88  ALA E CA  1 
ATOM   5133 C  C   . ALA D 4 92  ? 136.033 143.173 161.945 1.00 72.40  ? 88  ALA E C   1 
ATOM   5134 O  O   . ALA D 4 92  ? 137.075 143.723 161.578 1.00 72.40  ? 88  ALA E O   1 
ATOM   5135 C  CB  . ALA D 4 92  ? 133.726 143.172 160.977 1.00 72.40  ? 88  ALA E CB  1 
ATOM   5136 N  N   . LEU D 4 93  ? 135.980 141.917 162.379 1.00 70.43  ? 89  LEU E N   1 
ATOM   5137 C  CA  . LEU D 4 93  ? 137.122 141.017 162.384 1.00 70.43  ? 89  LEU E CA  1 
ATOM   5138 C  C   . LEU D 4 93  ? 136.981 140.054 161.213 1.00 70.43  ? 89  LEU E C   1 
ATOM   5139 O  O   . LEU D 4 93  ? 135.926 139.436 161.035 1.00 70.43  ? 89  LEU E O   1 
ATOM   5140 C  CB  . LEU D 4 93  ? 137.194 140.255 163.708 1.00 70.43  ? 89  LEU E CB  1 
ATOM   5141 C  CG  . LEU D 4 93  ? 138.374 139.327 163.992 1.00 70.43  ? 89  LEU E CG  1 
ATOM   5142 C  CD1 . LEU D 4 93  ? 139.668 140.108 164.037 1.00 70.43  ? 89  LEU E CD1 1 
ATOM   5143 C  CD2 . LEU D 4 93  ? 138.156 138.602 165.305 1.00 70.43  ? 89  LEU E CD2 1 
ATOM   5144 N  N   . TYR D 4 94  ? 138.036 139.944 160.412 1.00 71.90  ? 90  TYR E N   1 
ATOM   5145 C  CA  . TYR D 4 94  ? 138.040 139.133 159.203 1.00 71.90  ? 90  TYR E CA  1 
ATOM   5146 C  C   . TYR D 4 94  ? 138.768 137.823 159.466 1.00 71.90  ? 90  TYR E C   1 
ATOM   5147 O  O   . TYR D 4 94  ? 139.830 137.814 160.099 1.00 71.90  ? 90  TYR E O   1 
ATOM   5148 C  CB  . TYR D 4 94  ? 138.711 139.879 158.048 1.00 71.90  ? 90  TYR E CB  1 
ATOM   5149 C  CG  . TYR D 4 94  ? 137.847 140.936 157.400 1.00 71.90  ? 90  TYR E CG  1 
ATOM   5150 C  CD1 . TYR D 4 94  ? 136.928 140.602 156.415 1.00 71.90  ? 90  TYR E CD1 1 
ATOM   5151 C  CD2 . TYR D 4 94  ? 137.952 142.269 157.772 1.00 71.90  ? 90  TYR E CD2 1 
ATOM   5152 C  CE1 . TYR D 4 94  ? 136.139 141.567 155.819 1.00 71.90  ? 90  TYR E CE1 1 
ATOM   5153 C  CE2 . TYR D 4 94  ? 137.166 143.239 157.183 1.00 71.90  ? 90  TYR E CE2 1 
ATOM   5154 C  CZ  . TYR D 4 94  ? 136.261 142.882 156.208 1.00 71.90  ? 90  TYR E CZ  1 
ATOM   5155 O  OH  . TYR D 4 94  ? 135.476 143.846 155.618 1.00 71.90  ? 90  TYR E OH  1 
ATOM   5156 N  N   . TYR D 4 95  ? 138.197 136.726 158.975 1.00 66.72  ? 91  TYR E N   1 
ATOM   5157 C  CA  . TYR D 4 95  ? 138.774 135.397 159.082 1.00 66.72  ? 91  TYR E CA  1 
ATOM   5158 C  C   . TYR D 4 95  ? 139.015 134.848 157.683 1.00 66.72  ? 91  TYR E C   1 
ATOM   5159 O  O   . TYR D 4 95  ? 138.128 134.916 156.822 1.00 66.72  ? 91  TYR E O   1 
ATOM   5160 C  CB  . TYR D 4 95  ? 137.846 134.453 159.850 1.00 66.72  ? 91  TYR E CB  1 
ATOM   5161 C  CG  . TYR D 4 95  ? 137.692 134.757 161.322 1.00 66.72  ? 91  TYR E CG  1 
ATOM   5162 C  CD1 . TYR D 4 95  ? 138.798 134.987 162.126 1.00 66.72  ? 91  TYR E CD1 1 
ATOM   5163 C  CD2 . TYR D 4 95  ? 136.435 134.799 161.909 1.00 66.72  ? 91  TYR E CD2 1 
ATOM   5164 C  CE1 . TYR D 4 95  ? 138.655 135.257 163.473 1.00 66.72  ? 91  TYR E CE1 1 
ATOM   5165 C  CE2 . TYR D 4 95  ? 136.283 135.070 163.252 1.00 66.72  ? 91  TYR E CE2 1 
ATOM   5166 C  CZ  . TYR D 4 95  ? 137.396 135.298 164.029 1.00 66.72  ? 91  TYR E CZ  1 
ATOM   5167 O  OH  . TYR D 4 95  ? 137.246 135.565 165.370 1.00 66.72  ? 91  TYR E OH  1 
ATOM   5168 N  N   . CYS D 4 96  ? 140.209 134.307 157.465 1.00 65.33  ? 92  CYS E N   1 
ATOM   5169 C  CA  . CYS D 4 96  ? 140.555 133.601 156.239 1.00 65.33  ? 92  CYS E CA  1 
ATOM   5170 C  C   . CYS D 4 96  ? 140.191 132.133 156.413 1.00 65.33  ? 92  CYS E C   1 
ATOM   5171 O  O   . CYS D 4 96  ? 140.686 131.476 157.334 1.00 65.33  ? 92  CYS E O   1 
ATOM   5172 C  CB  . CYS D 4 96  ? 142.043 133.759 155.936 1.00 65.33  ? 92  CYS E CB  1 
ATOM   5173 S  SG  . CYS D 4 96  ? 142.620 132.957 154.436 1.00 65.33  ? 92  CYS E SG  1 
ATOM   5174 N  N   . ALA D 4 97  ? 139.329 131.621 155.539 1.00 61.87  ? 93  ALA E N   1 
ATOM   5175 C  CA  . ALA D 4 97  ? 138.802 130.273 155.676 1.00 61.87  ? 93  ALA E CA  1 
ATOM   5176 C  C   . ALA D 4 97  ? 139.072 129.455 154.421 1.00 61.87  ? 93  ALA E C   1 
ATOM   5177 O  O   . ALA D 4 97  ? 138.780 129.891 153.301 1.00 61.87  ? 93  ALA E O   1 
ATOM   5178 C  CB  . ALA D 4 97  ? 137.299 130.300 155.963 1.00 61.87  ? 93  ALA E CB  1 
ATOM   5179 N  N   . ARG D 4 98  ? 139.631 128.264 154.621 1.00 60.91  ? 94  ARG E N   1 
ATOM   5180 C  CA  . ARG D 4 98  ? 139.736 127.280 153.555 1.00 60.91  ? 94  ARG E CA  1 
ATOM   5181 C  C   . ARG D 4 98  ? 138.355 126.705 153.277 1.00 60.91  ? 94  ARG E C   1 
ATOM   5182 O  O   . ARG D 4 98  ? 137.655 126.275 154.200 1.00 60.91  ? 94  ARG E O   1 
ATOM   5183 C  CB  . ARG D 4 98  ? 140.713 126.173 153.945 1.00 60.91  ? 94  ARG E CB  1 
ATOM   5184 C  CG  . ARG D 4 98  ? 141.055 125.214 152.821 1.00 60.91  ? 94  ARG E CG  1 
ATOM   5185 C  CD  . ARG D 4 98  ? 141.892 124.055 153.334 1.00 60.91  ? 94  ARG E CD  1 
ATOM   5186 N  NE  . ARG D 4 98  ? 141.096 123.103 154.099 1.00 60.91  ? 94  ARG E NE  1 
ATOM   5187 C  CZ  . ARG D 4 98  ? 141.601 122.100 154.804 1.00 60.91  ? 94  ARG E CZ  1 
ATOM   5188 N  NH1 . ARG D 4 98  ? 142.905 121.888 154.869 1.00 60.91  ? 94  ARG E NH1 1 
ATOM   5189 N  NH2 . ARG D 4 98  ? 140.776 121.290 155.461 1.00 60.91  ? 94  ARG E NH2 1 
ATOM   5190 N  N   . THR D 4 99  ? 137.961 126.700 152.009 1.00 58.34  ? 95  THR E N   1 
ATOM   5191 C  CA  . THR D 4 99  ? 136.603 126.387 151.599 1.00 58.34  ? 95  THR E CA  1 
ATOM   5192 C  C   . THR D 4 99  ? 136.610 125.172 150.685 1.00 58.34  ? 95  THR E C   1 
ATOM   5193 O  O   . THR D 4 99  ? 137.376 125.121 149.714 1.00 58.34  ? 95  THR E O   1 
ATOM   5194 C  CB  . THR D 4 99  ? 135.968 127.578 150.877 1.00 58.34  ? 95  THR E CB  1 
ATOM   5195 O  OG1 . THR D 4 99  ? 135.953 128.715 151.749 1.00 58.34  ? 95  THR E OG1 1 
ATOM   5196 C  CG2 . THR D 4 99  ? 134.550 127.250 150.464 1.00 58.34  ? 95  THR E CG2 1 
ATOM   5197 N  N   . SER D 4 100 ? 135.757 124.205 150.999 1.00 53.47  ? 96  SER E N   1 
ATOM   5198 C  CA  . SER D 4 100 ? 135.528 123.031 150.176 1.00 53.47  ? 96  SER E CA  1 
ATOM   5199 C  C   . SER D 4 100 ? 134.082 123.034 149.698 1.00 53.47  ? 96  SER E C   1 
ATOM   5200 O  O   . SER D 4 100 ? 133.311 123.952 149.987 1.00 53.47  ? 96  SER E O   1 
ATOM   5201 C  CB  . SER D 4 100 ? 135.845 121.746 150.949 1.00 53.47  ? 96  SER E CB  1 
ATOM   5202 O  OG  . SER D 4 100 ? 135.219 121.753 152.219 1.00 53.47  ? 96  SER E OG  1 
ATOM   5203 N  N   . SER D 4 101 ? 133.714 121.994 148.958 1.00 52.71  ? 97  SER E N   1 
ATOM   5204 C  CA  . SER D 4 101 ? 132.398 121.910 148.347 1.00 52.71  ? 97  SER E CA  1 
ATOM   5205 C  C   . SER D 4 101 ? 131.739 120.578 148.673 1.00 52.71  ? 97  SER E C   1 
ATOM   5206 O  O   . SER D 4 101 ? 132.412 119.573 148.922 1.00 52.71  ? 97  SER E O   1 
ATOM   5207 C  CB  . SER D 4 101 ? 132.483 122.084 146.826 1.00 52.71  ? 97  SER E CB  1 
ATOM   5208 O  OG  . SER D 4 101 ? 131.192 122.164 146.248 1.00 52.71  ? 97  SER E OG  1 
ATOM   5209 N  N   . TRP D 4 102 ? 130.409 120.585 148.671 1.00 52.71  ? 98  TRP E N   1 
ATOM   5210 C  CA  . TRP D 4 102 ? 129.615 119.384 148.865 1.00 52.71  ? 98  TRP E CA  1 
ATOM   5211 C  C   . TRP D 4 102 ? 128.419 119.430 147.930 1.00 52.71  ? 98  TRP E C   1 
ATOM   5212 O  O   . TRP D 4 102 ? 127.787 120.478 147.771 1.00 52.71  ? 98  TRP E O   1 
ATOM   5213 C  CB  . TRP D 4 102 ? 129.137 119.246 150.316 1.00 52.71  ? 98  TRP E CB  1 
ATOM   5214 C  CG  . TRP D 4 102 ? 128.234 118.069 150.540 1.00 52.71  ? 98  TRP E CG  1 
ATOM   5215 C  CD1 . TRP D 4 102 ? 128.604 116.821 150.942 1.00 52.71  ? 98  TRP E CD1 1 
ATOM   5216 C  CD2 . TRP D 4 102 ? 126.810 118.032 150.377 1.00 52.71  ? 98  TRP E CD2 1 
ATOM   5217 N  NE1 . TRP D 4 102 ? 127.502 116.008 151.038 1.00 52.71  ? 98  TRP E NE1 1 
ATOM   5218 C  CE2 . TRP D 4 102 ? 126.388 116.728 150.697 1.00 52.71  ? 98  TRP E CE2 1 
ATOM   5219 C  CE3 . TRP D 4 102 ? 125.853 118.975 149.992 1.00 52.71  ? 98  TRP E CE3 1 
ATOM   5220 C  CZ2 . TRP D 4 102 ? 125.052 116.342 150.644 1.00 52.71  ? 98  TRP E CZ2 1 
ATOM   5221 C  CZ3 . TRP D 4 102 ? 124.526 118.589 149.940 1.00 52.71  ? 98  TRP E CZ3 1 
ATOM   5222 C  CH2 . TRP D 4 102 ? 124.138 117.284 150.264 1.00 52.71  ? 98  TRP E CH2 1 
ATOM   5223 N  N   . GLY D 4 103 ? 128.109 118.290 147.320 1.00 54.17  ? 99  GLY E N   1 
ATOM   5224 C  CA  . GLY D 4 103 ? 126.958 118.190 146.445 1.00 54.17  ? 99  GLY E CA  1 
ATOM   5225 C  C   . GLY D 4 103 ? 127.025 119.083 145.225 1.00 54.17  ? 99  GLY E C   1 
ATOM   5226 O  O   . GLY D 4 103 ? 126.046 119.755 144.887 1.00 54.17  ? 99  GLY E O   1 
ATOM   5227 N  N   . ASP D 4 104 ? 128.174 119.101 144.553 1.00 56.21  ? 100 ASP E N   1 
ATOM   5228 C  CA  . ASP D 4 104 ? 128.386 119.943 143.378 1.00 56.21  ? 100 ASP E CA  1 
ATOM   5229 C  C   . ASP D 4 104 ? 128.245 119.159 142.080 1.00 56.21  ? 100 ASP E C   1 
ATOM   5230 O  O   . ASP D 4 104 ? 128.927 119.449 141.093 1.00 56.21  ? 100 ASP E O   1 
ATOM   5231 C  CB  . ASP D 4 104 ? 129.752 120.617 143.452 1.00 56.21  ? 100 ASP E CB  1 
ATOM   5232 C  CG  . ASP D 4 104 ? 130.869 119.639 143.754 1.00 56.21  ? 100 ASP E CG  1 
ATOM   5233 O  OD1 . ASP D 4 104 ? 130.635 118.687 144.529 1.00 56.21  ? 100 ASP E OD1 1 
ATOM   5234 O  OD2 . ASP D 4 104 ? 131.982 119.823 143.218 1.00 56.21  ? 100 ASP E OD2 1 
ATOM   5235 N  N   . TYR D 4 105 A 127.364 118.163 142.050 1.00 58.31  ? 100 TYR E N   1 
ATOM   5236 C  CA  . TYR D 4 105 A 127.137 117.371 140.845 1.00 58.31  ? 100 TYR E CA  1 
ATOM   5237 C  C   . TYR D 4 105 A 126.041 118.031 140.019 1.00 58.31  ? 100 TYR E C   1 
ATOM   5238 O  O   . TYR D 4 105 A 124.857 117.936 140.357 1.00 58.31  ? 100 TYR E O   1 
ATOM   5239 C  CB  . TYR D 4 105 A 126.759 115.938 141.208 1.00 58.31  ? 100 TYR E CB  1 
ATOM   5240 C  CG  . TYR D 4 105 A 126.589 115.032 140.010 1.00 58.31  ? 100 TYR E CG  1 
ATOM   5241 C  CD1 . TYR D 4 105 A 125.463 114.233 139.873 1.00 58.31  ? 100 TYR E CD1 1 
ATOM   5242 C  CD2 . TYR D 4 105 A 127.555 114.978 139.014 1.00 58.31  ? 100 TYR E CD2 1 
ATOM   5243 C  CE1 . TYR D 4 105 A 125.304 113.405 138.780 1.00 58.31  ? 100 TYR E CE1 1 
ATOM   5244 C  CE2 . TYR D 4 105 A 127.405 114.153 137.916 1.00 58.31  ? 100 TYR E CE2 1 
ATOM   5245 C  CZ  . TYR D 4 105 A 126.278 113.368 137.805 1.00 58.31  ? 100 TYR E CZ  1 
ATOM   5246 O  OH  . TYR D 4 105 A 126.123 112.545 136.714 1.00 58.31  ? 100 TYR E OH  1 
ATOM   5247 N  N   . THR D 4 106 B 126.430 118.696 138.935 1.00 58.71  ? 100 THR E N   1 
ATOM   5248 C  CA  . THR D 4 106 B 125.495 119.370 138.046 1.00 58.71  ? 100 THR E CA  1 
ATOM   5249 C  C   . THR D 4 106 B 125.607 118.778 136.651 1.00 58.71  ? 100 THR E C   1 
ATOM   5250 O  O   . THR D 4 106 B 126.704 118.705 136.088 1.00 58.71  ? 100 THR E O   1 
ATOM   5251 C  CB  . THR D 4 106 B 125.759 120.874 137.994 1.00 58.71  ? 100 THR E CB  1 
ATOM   5252 O  OG1 . THR D 4 106 B 125.868 121.384 139.327 1.00 58.71  ? 100 THR E OG1 1 
ATOM   5253 C  CG2 . THR D 4 106 B 124.620 121.585 137.279 1.00 58.71  ? 100 THR E CG2 1 
ATOM   5254 N  N   . ARG D 4 107 C 124.472 118.357 136.100 1.00 59.11  ? 100 ARG E N   1 
ATOM   5255 C  CA  . ARG D 4 107 C 124.425 117.836 134.742 1.00 59.11  ? 100 ARG E CA  1 
ATOM   5256 C  C   . ARG D 4 107 C 124.475 118.934 133.689 1.00 59.11  ? 100 ARG E C   1 
ATOM   5257 O  O   . ARG D 4 107 C 125.046 118.724 132.612 1.00 59.11  ? 100 ARG E O   1 
ATOM   5258 C  CB  . ARG D 4 107 C 123.164 116.991 134.557 1.00 59.11  ? 100 ARG E CB  1 
ATOM   5259 C  CG  . ARG D 4 107 C 123.061 116.313 133.212 1.00 59.11  ? 100 ARG E CG  1 
ATOM   5260 C  CD  . ARG D 4 107 C 122.515 114.916 133.379 1.00 59.11  ? 100 ARG E CD  1 
ATOM   5261 N  NE  . ARG D 4 107 C 123.336 114.124 134.287 1.00 59.11  ? 100 ARG E NE  1 
ATOM   5262 C  CZ  . ARG D 4 107 C 122.859 113.363 135.262 1.00 59.11  ? 100 ARG E CZ  1 
ATOM   5263 N  NH1 . ARG D 4 107 C 121.561 113.281 135.503 1.00 59.11  ? 100 ARG E NH1 1 
ATOM   5264 N  NH2 . ARG D 4 107 C 123.706 112.670 136.017 1.00 59.11  ? 100 ARG E NH2 1 
ATOM   5265 N  N   . GLY D 4 108 D 123.904 120.098 133.976 1.00 55.62  ? 100 GLY E N   1 
ATOM   5266 C  CA  . GLY D 4 108 D 123.896 121.192 133.033 1.00 55.62  ? 100 GLY E CA  1 
ATOM   5267 C  C   . GLY D 4 108 D 125.237 121.884 132.955 1.00 55.62  ? 100 GLY E C   1 
ATOM   5268 O  O   . GLY D 4 108 D 126.189 121.576 133.688 1.00 55.62  ? 100 GLY E O   1 
ATOM   5269 N  N   . PRO D 4 109 E 125.331 122.851 132.039 1.00 55.04  ? 100 PRO E N   1 
ATOM   5270 C  CA  . PRO D 4 109 E 126.617 123.536 131.840 1.00 55.04  ? 100 PRO E CA  1 
ATOM   5271 C  C   . PRO D 4 109 E 127.006 124.442 132.993 1.00 55.04  ? 100 PRO E C   1 
ATOM   5272 O  O   . PRO D 4 109 E 128.203 124.682 133.196 1.00 55.04  ? 100 PRO E O   1 
ATOM   5273 C  CB  . PRO D 4 109 E 126.400 124.335 130.548 1.00 55.04  ? 100 PRO E CB  1 
ATOM   5274 C  CG  . PRO D 4 109 E 124.926 124.485 130.416 1.00 55.04  ? 100 PRO E CG  1 
ATOM   5275 C  CD  . PRO D 4 109 E 124.259 123.382 131.182 1.00 55.04  ? 100 PRO E CD  1 
ATOM   5276 N  N   . GLU D 4 110 F 126.045 124.950 133.750 1.00 57.84  ? 100 GLU E N   1 
ATOM   5277 C  CA  . GLU D 4 110 F 126.349 125.899 134.815 1.00 57.84  ? 100 GLU E CA  1 
ATOM   5278 C  C   . GLU D 4 110 F 126.913 125.175 136.030 1.00 57.84  ? 100 GLU E C   1 
ATOM   5279 O  O   . GLU D 4 110 F 126.246 124.286 136.573 1.00 57.84  ? 100 GLU E O   1 
ATOM   5280 C  CB  . GLU D 4 110 F 125.093 126.676 135.199 1.00 57.84  ? 100 GLU E CB  1 
ATOM   5281 C  CG  . GLU D 4 110 F 124.540 127.554 134.089 1.00 57.84  ? 100 GLU E CG  1 
ATOM   5282 C  CD  . GLU D 4 110 F 125.460 128.708 133.743 1.00 57.84  ? 100 GLU E CD  1 
ATOM   5283 O  OE1 . GLU D 4 110 F 126.156 129.210 134.650 1.00 57.84  ? 100 GLU E OE1 1 
ATOM   5284 O  OE2 . GLU D 4 110 F 125.486 129.114 132.562 1.00 57.84  ? 100 GLU E OE2 1 
ATOM   5285 N  N   . PRO D 4 111 G 128.120 125.508 136.484 1.00 56.56  ? 100 PRO E N   1 
ATOM   5286 C  CA  . PRO D 4 111 G 128.640 124.892 137.709 1.00 56.56  ? 100 PRO E CA  1 
ATOM   5287 C  C   . PRO D 4 111 G 127.825 125.305 138.925 1.00 56.56  ? 100 PRO E C   1 
ATOM   5288 O  O   . PRO D 4 111 G 127.285 126.411 138.994 1.00 56.56  ? 100 PRO E O   1 
ATOM   5289 C  CB  . PRO D 4 111 G 130.078 125.420 137.796 1.00 56.56  ? 100 PRO E CB  1 
ATOM   5290 C  CG  . PRO D 4 111 G 130.390 125.963 136.439 1.00 56.56  ? 100 PRO E CG  1 
ATOM   5291 C  CD  . PRO D 4 111 G 129.092 126.423 135.866 1.00 56.56  ? 100 PRO E CD  1 
ATOM   5292 N  N   . LYS D 4 112 H 127.740 124.397 139.893 1.00 55.64  ? 100 LYS E N   1 
ATOM   5293 C  CA  . LYS D 4 112 H 127.067 124.657 141.159 1.00 55.64  ? 100 LYS E CA  1 
ATOM   5294 C  C   . LYS D 4 112 H 128.114 124.996 142.210 1.00 55.64  ? 100 LYS E C   1 
ATOM   5295 O  O   . LYS D 4 112 H 128.995 124.179 142.500 1.00 55.64  ? 100 LYS E O   1 
ATOM   5296 C  CB  . LYS D 4 112 H 126.237 123.454 141.601 1.00 55.64  ? 100 LYS E CB  1 
ATOM   5297 C  CG  . LYS D 4 112 H 124.740 123.639 141.449 1.00 55.64  ? 100 LYS E CG  1 
ATOM   5298 C  CD  . LYS D 4 112 H 123.990 122.375 141.834 1.00 55.64  ? 100 LYS E CD  1 
ATOM   5299 C  CE  . LYS D 4 112 H 124.172 122.051 143.305 1.00 55.64  ? 100 LYS E CE  1 
ATOM   5300 N  NZ  . LYS D 4 112 H 123.351 120.880 143.720 1.00 55.64  ? 100 LYS E NZ  1 
ATOM   5301 N  N   . ILE D 4 113 I 128.019 126.194 142.775 1.00 57.42  ? 100 ILE E N   1 
ATOM   5302 C  CA  . ILE D 4 113 I 128.952 126.650 143.801 1.00 57.42  ? 100 ILE E CA  1 
ATOM   5303 C  C   . ILE D 4 113 I 128.242 126.476 145.139 1.00 57.42  ? 100 ILE E C   1 
ATOM   5304 O  O   . ILE D 4 113 I 127.515 127.354 145.609 1.00 57.42  ? 100 ILE E O   1 
ATOM   5305 C  CB  . ILE D 4 113 I 129.407 128.088 143.562 1.00 57.42  ? 100 ILE E CB  1 
ATOM   5306 C  CG1 . ILE D 4 113 I 130.174 128.184 142.243 1.00 57.42  ? 100 ILE E CG1 1 
ATOM   5307 C  CG2 . ILE D 4 113 I 130.283 128.568 144.707 1.00 57.42  ? 100 ILE E CG2 1 
ATOM   5308 C  CD1 . ILE D 4 113 I 131.533 127.522 142.281 1.00 57.42  ? 100 ILE E CD1 1 
ATOM   5309 N  N   . THR D 4 114 J 128.445 125.315 145.754 1.00 55.20  ? 100 THR E N   1 
ATOM   5310 C  CA  . THR D 4 114 J 127.980 125.035 147.106 1.00 55.20  ? 100 THR E CA  1 
ATOM   5311 C  C   . THR D 4 114 J 129.206 124.928 148.000 1.00 55.20  ? 100 THR E C   1 
ATOM   5312 O  O   . THR D 4 114 J 130.035 124.033 147.814 1.00 55.20  ? 100 THR E O   1 
ATOM   5313 C  CB  . THR D 4 114 J 127.157 123.749 147.154 1.00 55.20  ? 100 THR E CB  1 
ATOM   5314 O  OG1 . THR D 4 114 J 127.978 122.640 146.767 1.00 55.20  ? 100 THR E OG1 1 
ATOM   5315 C  CG2 . THR D 4 114 J 125.972 123.845 146.209 1.00 55.20  ? 100 THR E CG2 1 
ATOM   5316 N  N   . TRP D 4 115 K 129.319 125.836 148.965 1.00 56.12  ? 100 TRP E N   1 
ATOM   5317 C  CA  . TRP D 4 115 K 130.548 126.003 149.723 1.00 56.12  ? 100 TRP E CA  1 
ATOM   5318 C  C   . TRP D 4 115 K 130.290 125.870 151.216 1.00 56.12  ? 100 TRP E C   1 
ATOM   5319 O  O   . TRP D 4 115 K 129.254 126.300 151.730 1.00 56.12  ? 100 TRP E O   1 
ATOM   5320 C  CB  . TRP D 4 115 K 131.192 127.364 149.437 1.00 56.12  ? 100 TRP E CB  1 
ATOM   5321 C  CG  . TRP D 4 115 K 131.945 127.417 148.147 1.00 56.12  ? 100 TRP E CG  1 
ATOM   5322 C  CD1 . TRP D 4 115 K 132.076 126.415 147.234 1.00 56.12  ? 100 TRP E CD1 1 
ATOM   5323 C  CD2 . TRP D 4 115 K 132.683 128.530 147.630 1.00 56.12  ? 100 TRP E CD2 1 
ATOM   5324 N  NE1 . TRP D 4 115 K 132.846 126.835 146.178 1.00 56.12  ? 100 TRP E NE1 1 
ATOM   5325 C  CE2 . TRP D 4 115 K 133.232 128.130 146.398 1.00 56.12  ? 100 TRP E CE2 1 
ATOM   5326 C  CE3 . TRP D 4 115 K 132.931 129.826 148.089 1.00 56.12  ? 100 TRP E CE3 1 
ATOM   5327 C  CZ2 . TRP D 4 115 K 134.012 128.980 145.618 1.00 56.12  ? 100 TRP E CZ2 1 
ATOM   5328 C  CZ3 . TRP D 4 115 K 133.706 130.668 147.314 1.00 56.12  ? 100 TRP E CZ3 1 
ATOM   5329 C  CH2 . TRP D 4 115 K 134.238 130.242 146.093 1.00 56.12  ? 100 TRP E CH2 1 
ATOM   5330 N  N   . TYR D 4 116 L 131.256 125.266 151.905 1.00 56.02  ? 100 TYR E N   1 
ATOM   5331 C  CA  . TYR D 4 116 L 131.280 125.231 153.358 1.00 56.02  ? 100 TYR E CA  1 
ATOM   5332 C  C   . TYR D 4 116 L 132.728 125.343 153.810 1.00 56.02  ? 100 TYR E C   1 
ATOM   5333 O  O   . TYR D 4 116 L 133.650 124.908 153.116 1.00 56.02  ? 100 TYR E O   1 
ATOM   5334 C  CB  . TYR D 4 116 L 130.615 123.962 153.911 1.00 56.02  ? 100 TYR E CB  1 
ATOM   5335 C  CG  . TYR D 4 116 L 131.384 122.683 153.668 1.00 56.02  ? 100 TYR E CG  1 
ATOM   5336 C  CD1 . TYR D 4 116 L 131.248 121.984 152.476 1.00 56.02  ? 100 TYR E CD1 1 
ATOM   5337 C  CD2 . TYR D 4 116 L 132.233 122.165 154.636 1.00 56.02  ? 100 TYR E CD2 1 
ATOM   5338 C  CE1 . TYR D 4 116 L 131.945 120.812 152.252 1.00 56.02  ? 100 TYR E CE1 1 
ATOM   5339 C  CE2 . TYR D 4 116 L 132.933 120.995 154.421 1.00 56.02  ? 100 TYR E CE2 1 
ATOM   5340 C  CZ  . TYR D 4 116 L 132.784 120.322 153.229 1.00 56.02  ? 100 TYR E CZ  1 
ATOM   5341 O  OH  . TYR D 4 116 L 133.480 119.156 153.011 1.00 56.02  ? 100 TYR E OH  1 
ATOM   5342 N  N   . PHE D 4 117 M 132.920 125.930 154.986 1.00 57.98  ? 100 PHE E N   1 
ATOM   5343 C  CA  . PHE D 4 117 M 134.241 126.291 155.483 1.00 57.98  ? 100 PHE E CA  1 
ATOM   5344 C  C   . PHE D 4 117 M 134.689 125.290 156.537 1.00 57.98  ? 100 PHE E C   1 
ATOM   5345 O  O   . PHE D 4 117 M 133.892 124.878 157.387 1.00 57.98  ? 100 PHE E O   1 
ATOM   5346 C  CB  . PHE D 4 117 M 134.236 127.708 156.064 1.00 57.98  ? 100 PHE E CB  1 
ATOM   5347 C  CG  . PHE D 4 117 M 133.583 128.727 155.172 1.00 57.98  ? 100 PHE E CG  1 
ATOM   5348 C  CD1 . PHE D 4 117 M 132.219 128.959 155.239 1.00 57.98  ? 100 PHE E CD1 1 
ATOM   5349 C  CD2 . PHE D 4 117 M 134.333 129.449 154.263 1.00 57.98  ? 100 PHE E CD2 1 
ATOM   5350 C  CE1 . PHE D 4 117 M 131.621 129.895 154.418 1.00 57.98  ? 100 PHE E CE1 1 
ATOM   5351 C  CE2 . PHE D 4 117 M 133.739 130.384 153.440 1.00 57.98  ? 100 PHE E CE2 1 
ATOM   5352 C  CZ  . PHE D 4 117 M 132.382 130.606 153.518 1.00 57.98  ? 100 PHE E CZ  1 
ATOM   5353 N  N   . ASP D 4 118 ? 135.961 124.899 156.477 1.00 60.01  ? 101 ASP E N   1 
ATOM   5354 C  CA  . ASP D 4 118 ? 136.533 123.928 157.400 1.00 60.01  ? 101 ASP E CA  1 
ATOM   5355 C  C   . ASP D 4 118 ? 137.647 124.506 158.259 1.00 60.01  ? 101 ASP E C   1 
ATOM   5356 O  O   . ASP D 4 118 ? 137.629 124.348 159.483 1.00 60.01  ? 101 ASP E O   1 
ATOM   5357 C  CB  . ASP D 4 118 ? 137.053 122.709 156.623 1.00 60.01  ? 101 ASP E CB  1 
ATOM   5358 C  CG  . ASP D 4 118 ? 137.832 123.096 155.381 1.00 60.01  ? 101 ASP E CG  1 
ATOM   5359 O  OD1 . ASP D 4 118 ? 138.728 123.960 155.482 1.00 60.01  ? 101 ASP E OD1 1 
ATOM   5360 O  OD2 . ASP D 4 118 ? 137.550 122.534 154.302 1.00 60.01  ? 101 ASP E OD2 1 
ATOM   5361 N  N   . LEU D 4 119 ? 138.622 125.173 157.649 1.00 62.07  ? 102 LEU E N   1 
ATOM   5362 C  CA  . LEU D 4 119 ? 139.775 125.715 158.356 1.00 62.07  ? 102 LEU E CA  1 
ATOM   5363 C  C   . LEU D 4 119 ? 139.652 127.230 158.445 1.00 62.07  ? 102 LEU E C   1 
ATOM   5364 O  O   . LEU D 4 119 ? 139.275 127.884 157.467 1.00 62.07  ? 102 LEU E O   1 
ATOM   5365 C  CB  . LEU D 4 119 ? 141.076 125.327 157.653 1.00 62.07  ? 102 LEU E CB  1 
ATOM   5366 C  CG  . LEU D 4 119 ? 142.348 125.382 158.495 1.00 62.07  ? 102 LEU E CG  1 
ATOM   5367 C  CD1 . LEU D 4 119 ? 142.308 124.326 159.586 1.00 62.07  ? 102 LEU E CD1 1 
ATOM   5368 C  CD2 . LEU D 4 119 ? 143.570 125.198 157.612 1.00 62.07  ? 102 LEU E CD2 1 
ATOM   5369 N  N   . TRP D 4 120 ? 139.967 127.781 159.613 1.00 60.36  ? 103 TRP E N   1 
ATOM   5370 C  CA  . TRP D 4 120 ? 139.857 129.209 159.867 1.00 60.36  ? 103 TRP E CA  1 
ATOM   5371 C  C   . TRP D 4 120 ? 141.182 129.749 160.390 1.00 60.36  ? 103 TRP E C   1 
ATOM   5372 O  O   . TRP D 4 120 ? 142.172 129.024 160.519 1.00 60.36  ? 103 TRP E O   1 
ATOM   5373 C  CB  . TRP D 4 120 ? 138.729 129.508 160.862 1.00 60.36  ? 103 TRP E CB  1 
ATOM   5374 C  CG  . TRP D 4 120 ? 137.367 129.125 160.367 1.00 60.36  ? 103 TRP E CG  1 
ATOM   5375 C  CD1 . TRP D 4 120 ? 136.920 127.867 160.091 1.00 60.36  ? 103 TRP E CD1 1 
ATOM   5376 C  CD2 . TRP D 4 120 ? 136.275 130.009 160.086 1.00 60.36  ? 103 TRP E CD2 1 
ATOM   5377 N  NE1 . TRP D 4 120 ? 135.617 127.911 159.658 1.00 60.36  ? 103 TRP E NE1 1 
ATOM   5378 C  CE2 . TRP D 4 120 ? 135.198 129.215 159.647 1.00 60.36  ? 103 TRP E CE2 1 
ATOM   5379 C  CE3 . TRP D 4 120 ? 136.104 131.393 160.165 1.00 60.36  ? 103 TRP E CE3 1 
ATOM   5380 C  CZ2 . TRP D 4 120 ? 133.969 129.760 159.287 1.00 60.36  ? 103 TRP E CZ2 1 
ATOM   5381 C  CZ3 . TRP D 4 120 ? 134.883 131.931 159.809 1.00 60.36  ? 103 TRP E CZ3 1 
ATOM   5382 C  CH2 . TRP D 4 120 ? 133.831 131.116 159.375 1.00 60.36  ? 103 TRP E CH2 1 
ATOM   5383 N  N   . GLY D 4 121 ? 141.191 131.049 160.692 1.00 68.45  ? 104 GLY E N   1 
ATOM   5384 C  CA  . GLY D 4 121 ? 142.381 131.723 161.165 1.00 68.45  ? 104 GLY E CA  1 
ATOM   5385 C  C   . GLY D 4 121 ? 142.071 132.670 162.312 1.00 68.45  ? 104 GLY E C   1 
ATOM   5386 O  O   . GLY D 4 121 ? 140.938 132.753 162.789 1.00 68.45  ? 104 GLY E O   1 
ATOM   5387 N  N   . ARG D 4 122 ? 143.115 133.383 162.740 1.00 75.34  ? 105 ARG E N   1 
ATOM   5388 C  CA  . ARG D 4 122 ? 142.984 134.304 163.864 1.00 75.34  ? 105 ARG E CA  1 
ATOM   5389 C  C   . ARG D 4 122 ? 142.188 135.553 163.505 1.00 75.34  ? 105 ARG E C   1 
ATOM   5390 O  O   . ARG D 4 122 ? 141.479 136.094 164.361 1.00 75.34  ? 105 ARG E O   1 
ATOM   5391 C  CB  . ARG D 4 122 ? 144.368 134.695 164.384 1.00 75.34  ? 105 ARG E CB  1 
ATOM   5392 C  CG  . ARG D 4 122 ? 145.315 133.519 164.556 1.00 75.34  ? 105 ARG E CG  1 
ATOM   5393 C  CD  . ARG D 4 122 ? 144.897 132.646 165.728 1.00 75.34  ? 105 ARG E CD  1 
ATOM   5394 N  NE  . ARG D 4 122 ? 145.841 131.561 165.969 1.00 75.34  ? 105 ARG E NE  1 
ATOM   5395 C  CZ  . ARG D 4 122 ? 145.803 130.386 165.355 1.00 75.34  ? 105 ARG E CZ  1 
ATOM   5396 N  NH1 . ARG D 4 122 ? 144.876 130.107 164.454 1.00 75.34  ? 105 ARG E NH1 1 
ATOM   5397 N  NH2 . ARG D 4 122 ? 146.717 129.468 165.655 1.00 75.34  ? 105 ARG E NH2 1 
ATOM   5398 N  N   . GLY D 4 123 ? 142.296 136.030 162.266 1.00 74.90  ? 106 GLY E N   1 
ATOM   5399 C  CA  . GLY D 4 123 ? 141.538 137.186 161.834 1.00 74.90  ? 106 GLY E CA  1 
ATOM   5400 C  C   . GLY D 4 123 ? 142.235 138.499 162.134 1.00 74.90  ? 106 GLY E C   1 
ATOM   5401 O  O   . GLY D 4 123 ? 143.128 138.599 162.977 1.00 74.90  ? 106 GLY E O   1 
ATOM   5402 N  N   . THR D 4 124 ? 141.806 139.537 161.416 1.00 74.12  ? 107 THR E N   1 
ATOM   5403 C  CA  . THR D 4 124 ? 142.372 140.871 161.568 1.00 74.12  ? 107 THR E CA  1 
ATOM   5404 C  C   . THR D 4 124 ? 141.249 141.892 161.688 1.00 74.12  ? 107 THR E C   1 
ATOM   5405 O  O   . THR D 4 124 ? 140.167 141.713 161.128 1.00 74.12  ? 107 THR E O   1 
ATOM   5406 C  CB  . THR D 4 124 ? 143.287 141.241 160.394 1.00 74.12  ? 107 THR E CB  1 
ATOM   5407 O  OG1 . THR D 4 124 ? 142.568 141.104 159.162 1.00 74.12  ? 107 THR E OG1 1 
ATOM   5408 C  CG2 . THR D 4 124 ? 144.518 140.347 160.366 1.00 74.12  ? 107 THR E CG2 1 
ATOM   5409 N  N   . LEU D 4 125 ? 141.521 142.969 162.420 1.00 74.51  ? 108 LEU E N   1 
ATOM   5410 C  CA  . LEU D 4 125 ? 140.509 143.967 162.736 1.00 74.51  ? 108 LEU E CA  1 
ATOM   5411 C  C   . LEU D 4 125 ? 140.530 145.102 161.719 1.00 74.51  ? 108 LEU E C   1 
ATOM   5412 O  O   . LEU D 4 125 ? 141.598 145.577 161.322 1.00 74.51  ? 108 LEU E O   1 
ATOM   5413 C  CB  . LEU D 4 125 ? 140.734 144.517 164.147 1.00 74.51  ? 108 LEU E CB  1 
ATOM   5414 C  CG  . LEU D 4 125 ? 139.711 145.501 164.715 1.00 74.51  ? 108 LEU E CG  1 
ATOM   5415 C  CD1 . LEU D 4 125 ? 139.425 145.182 166.172 1.00 74.51  ? 108 LEU E CD1 1 
ATOM   5416 C  CD2 . LEU D 4 125 ? 140.214 146.928 164.576 1.00 74.51  ? 108 LEU E CD2 1 
ATOM   5417 N  N   . VAL D 4 126 ? 139.341 145.532 161.298 1.00 72.99  ? 109 VAL E N   1 
ATOM   5418 C  CA  . VAL D 4 126 ? 139.186 146.625 160.342 1.00 72.99  ? 109 VAL E CA  1 
ATOM   5419 C  C   . VAL D 4 126 ? 138.098 147.560 160.852 1.00 72.99  ? 109 VAL E C   1 
ATOM   5420 O  O   . VAL D 4 126 ? 136.912 147.216 160.819 1.00 72.99  ? 109 VAL E O   1 
ATOM   5421 C  CB  . VAL D 4 126 ? 138.836 146.110 158.932 1.00 72.99  ? 109 VAL E CB  1 
ATOM   5422 C  CG1 . VAL D 4 126 ? 138.534 147.270 158.004 1.00 72.99  ? 109 VAL E CG1 1 
ATOM   5423 C  CG2 . VAL D 4 126 ? 139.970 145.266 158.375 1.00 72.99  ? 109 VAL E CG2 1 
ATOM   5424 N  N   . THR D 4 127 ? 138.497 148.741 161.320 1.00 76.91  ? 110 THR E N   1 
ATOM   5425 C  CA  . THR D 4 127 ? 137.562 149.720 161.854 1.00 76.91  ? 110 THR E CA  1 
ATOM   5426 C  C   . THR D 4 127 ? 137.543 150.950 160.959 1.00 76.91  ? 110 THR E C   1 
ATOM   5427 O  O   . THR D 4 127 ? 138.596 151.502 160.629 1.00 76.91  ? 110 THR E O   1 
ATOM   5428 C  CB  . THR D 4 127 ? 137.929 150.125 163.289 1.00 76.91  ? 110 THR E CB  1 
ATOM   5429 O  OG1 . THR D 4 127 ? 137.787 148.995 164.158 1.00 76.91  ? 110 THR E OG1 1 
ATOM   5430 C  CG2 . THR D 4 127 ? 137.027 151.248 163.779 1.00 76.91  ? 110 THR E CG2 1 
ATOM   5431 N  N   . VAL D 4 128 ? 136.345 151.376 160.570 1.00 76.77  ? 111 VAL E N   1 
ATOM   5432 C  CA  . VAL D 4 128 ? 136.165 152.553 159.730 1.00 76.77  ? 111 VAL E CA  1 
ATOM   5433 C  C   . VAL D 4 128 ? 135.413 153.606 160.532 1.00 76.77  ? 111 VAL E C   1 
ATOM   5434 O  O   . VAL D 4 128 ? 134.233 153.426 160.859 1.00 76.77  ? 111 VAL E O   1 
ATOM   5435 C  CB  . VAL D 4 128 ? 135.418 152.210 158.433 1.00 76.77  ? 111 VAL E CB  1 
ATOM   5436 C  CG1 . VAL D 4 128 ? 135.153 153.473 157.629 1.00 76.77  ? 111 VAL E CG1 1 
ATOM   5437 C  CG2 . VAL D 4 128 ? 136.214 151.208 157.617 1.00 76.77  ? 111 VAL E CG2 1 
ATOM   5438 N  N   . SER D 4 129 ? 136.093 154.707 160.845 1.00 81.80  ? 112 SER E N   1 
ATOM   5439 C  CA  . SER D 4 129 ? 135.497 155.815 161.579 1.00 81.80  ? 112 SER E CA  1 
ATOM   5440 C  C   . SER D 4 129 ? 136.021 157.122 161.006 1.00 81.80  ? 112 SER E C   1 
ATOM   5441 O  O   . SER D 4 129 ? 137.133 157.164 160.471 1.00 81.80  ? 112 SER E O   1 
ATOM   5442 C  CB  . SER D 4 129 ? 135.813 155.726 163.077 1.00 81.80  ? 112 SER E CB  1 
ATOM   5443 O  OG  . SER D 4 129 ? 137.201 155.880 163.315 1.00 81.80  ? 112 SER E OG  1 
ATOM   5444 N  N   . SER D 4 130 ? 135.222 158.181 161.119 1.00 83.63  ? 113 SER E N   1 
ATOM   5445 C  CA  . SER D 4 130 ? 135.599 159.496 160.599 1.00 83.63  ? 113 SER E CA  1 
ATOM   5446 C  C   . SER D 4 130 ? 136.402 160.276 161.643 1.00 83.63  ? 113 SER E C   1 
ATOM   5447 O  O   . SER D 4 130 ? 135.980 161.312 162.158 1.00 83.63  ? 113 SER E O   1 
ATOM   5448 C  CB  . SER D 4 130 ? 134.358 160.265 160.162 1.00 83.63  ? 113 SER E CB  1 
ATOM   5449 O  OG  . SER D 4 130 ? 134.710 161.435 159.444 1.00 83.63  ? 113 SER E OG  1 
ATOM   5450 N  N   . ALA D 4 131 ? 137.586 159.753 161.946 1.00 79.50  ? 114 ALA E N   1 
ATOM   5451 C  CA  . ALA D 4 131 ? 138.475 160.377 162.919 1.00 79.50  ? 114 ALA E CA  1 
ATOM   5452 C  C   . ALA D 4 131 ? 139.919 159.943 162.692 1.00 79.50  ? 114 ALA E C   1 
ATOM   5453 O  O   . ALA D 4 131 ? 140.182 158.994 161.956 1.00 79.50  ? 114 ALA E O   1 
ATOM   5454 C  CB  . ALA D 4 131 ? 138.036 160.037 164.334 1.00 79.50  ? 114 ALA E CB  1 
ATOM   5455 N  N   . ASP E 5 2   ? 117.333 134.466 148.865 1.00 77.80  ? 1   ASP F N   1 
ATOM   5456 C  CA  . ASP E 5 2   ? 116.190 134.962 149.623 1.00 77.80  ? 1   ASP F CA  1 
ATOM   5457 C  C   . ASP E 5 2   ? 115.639 133.890 150.559 1.00 77.80  ? 1   ASP F C   1 
ATOM   5458 O  O   . ASP E 5 2   ? 114.425 133.745 150.705 1.00 77.80  ? 1   ASP F O   1 
ATOM   5459 C  CB  . ASP E 5 2   ? 115.091 135.455 148.678 1.00 77.80  ? 1   ASP F CB  1 
ATOM   5460 C  CG  . ASP E 5 2   ? 114.648 134.392 147.689 1.00 77.80  ? 1   ASP F CG  1 
ATOM   5461 O  OD1 . ASP E 5 2   ? 115.297 133.327 147.622 1.00 77.80  ? 1   ASP F OD1 1 
ATOM   5462 O  OD2 . ASP E 5 2   ? 113.649 134.624 146.976 1.00 77.80  ? 1   ASP F OD2 1 
ATOM   5463 N  N   . ILE E 5 3   ? 116.539 133.142 151.192 1.00 72.81  ? 2   ILE F N   1 
ATOM   5464 C  CA  . ILE E 5 3   ? 116.178 132.077 152.118 1.00 72.81  ? 2   ILE F CA  1 
ATOM   5465 C  C   . ILE E 5 3   ? 116.494 132.547 153.530 1.00 72.81  ? 2   ILE F C   1 
ATOM   5466 O  O   . ILE E 5 3   ? 117.642 132.894 153.832 1.00 72.81  ? 2   ILE F O   1 
ATOM   5467 C  CB  . ILE E 5 3   ? 116.920 130.767 151.797 1.00 72.81  ? 2   ILE F CB  1 
ATOM   5468 C  CG1 . ILE E 5 3   ? 116.284 130.080 150.588 1.00 72.81  ? 2   ILE F CG1 1 
ATOM   5469 C  CG2 . ILE E 5 3   ? 116.911 129.838 152.998 1.00 72.81  ? 2   ILE F CG2 1 
ATOM   5470 C  CD1 . ILE E 5 3   ? 114.883 129.580 150.844 1.00 72.81  ? 2   ILE F CD1 1 
ATOM   5471 N  N   . GLN E 5 4   ? 115.478 132.564 154.387 1.00 73.64  ? 3   GLN F N   1 
ATOM   5472 C  CA  . GLN E 5 4   ? 115.663 132.991 155.763 1.00 73.64  ? 3   GLN F CA  1 
ATOM   5473 C  C   . GLN E 5 4   ? 116.387 131.914 156.566 1.00 73.64  ? 3   GLN F C   1 
ATOM   5474 O  O   . GLN E 5 4   ? 116.456 130.748 156.172 1.00 73.64  ? 3   GLN F O   1 
ATOM   5475 C  CB  . GLN E 5 4   ? 114.316 133.317 156.409 1.00 73.64  ? 3   GLN F CB  1 
ATOM   5476 C  CG  . GLN E 5 4   ? 113.868 134.757 156.216 1.00 73.64  ? 3   GLN F CG  1 
ATOM   5477 C  CD  . GLN E 5 4   ? 113.451 135.057 154.789 1.00 73.64  ? 3   GLN F CD  1 
ATOM   5478 O  OE1 . GLN E 5 4   ? 113.218 134.148 153.992 1.00 73.64  ? 3   GLN F OE1 1 
ATOM   5479 N  NE2 . GLN E 5 4   ? 113.357 136.340 154.458 1.00 73.64  ? 3   GLN F NE2 1 
ATOM   5480 N  N   . LEU E 5 5   ? 116.938 132.326 157.709 1.00 67.18  ? 4   LEU F N   1 
ATOM   5481 C  CA  . LEU E 5 5   ? 117.672 131.413 158.585 1.00 67.18  ? 4   LEU F CA  1 
ATOM   5482 C  C   . LEU E 5 5   ? 117.590 131.970 160.004 1.00 67.18  ? 4   LEU F C   1 
ATOM   5483 O  O   . LEU E 5 5   ? 118.302 132.921 160.338 1.00 67.18  ? 4   LEU F O   1 
ATOM   5484 C  CB  . LEU E 5 5   ? 119.117 131.256 158.133 1.00 67.18  ? 4   LEU F CB  1 
ATOM   5485 C  CG  . LEU E 5 5   ? 119.448 130.118 157.166 1.00 67.18  ? 4   LEU F CG  1 
ATOM   5486 C  CD1 . LEU E 5 5   ? 120.952 129.938 157.054 1.00 67.18  ? 4   LEU F CD1 1 
ATOM   5487 C  CD2 . LEU E 5 5   ? 118.781 128.825 157.604 1.00 67.18  ? 4   LEU F CD2 1 
ATOM   5488 N  N   . THR E 5 6   ? 116.727 131.377 160.827 1.00 68.89  ? 5   THR F N   1 
ATOM   5489 C  CA  . THR E 5 6   ? 116.584 131.772 162.225 1.00 68.89  ? 5   THR F CA  1 
ATOM   5490 C  C   . THR E 5 6   ? 116.787 130.541 163.092 1.00 68.89  ? 5   THR F C   1 
ATOM   5491 O  O   . THR E 5 6   ? 116.199 129.491 162.824 1.00 68.89  ? 5   THR F O   1 
ATOM   5492 C  CB  . THR E 5 6   ? 115.211 132.397 162.494 1.00 68.89  ? 5   THR F CB  1 
ATOM   5493 O  OG1 . THR E 5 6   ? 114.193 131.398 162.361 1.00 68.89  ? 5   THR F OG1 1 
ATOM   5494 C  CG2 . THR E 5 6   ? 114.935 133.532 161.517 1.00 68.89  ? 5   THR F CG2 1 
ATOM   5495 N  N   . GLN E 5 7   ? 117.611 130.662 164.128 1.00 63.54  ? 6   GLN F N   1 
ATOM   5496 C  CA  . GLN E 5 7   ? 117.943 129.526 164.978 1.00 63.54  ? 6   GLN F CA  1 
ATOM   5497 C  C   . GLN E 5 7   ? 117.572 129.830 166.422 1.00 63.54  ? 6   GLN F C   1 
ATOM   5498 O  O   . GLN E 5 7   ? 117.718 130.967 166.883 1.00 63.54  ? 6   GLN F O   1 
ATOM   5499 C  CB  . GLN E 5 7   ? 119.424 129.164 164.851 1.00 63.54  ? 6   GLN F CB  1 
ATOM   5500 C  CG  . GLN E 5 7   ? 120.374 130.335 164.940 1.00 63.54  ? 6   GLN F CG  1 
ATOM   5501 C  CD  . GLN E 5 7   ? 121.796 129.894 165.200 1.00 63.54  ? 6   GLN F CD  1 
ATOM   5502 O  OE1 . GLN E 5 7   ? 122.576 129.700 164.269 1.00 63.54  ? 6   GLN F OE1 1 
ATOM   5503 N  NE2 . GLN E 5 7   ? 122.140 129.722 166.467 1.00 63.54  ? 6   GLN F NE2 1 
ATOM   5504 N  N   . SER E 5 8   ? 117.094 128.810 167.121 1.00 67.97  ? 7   SER F N   1 
ATOM   5505 C  CA  . SER E 5 8   ? 116.551 128.917 168.464 1.00 67.97  ? 7   SER F CA  1 
ATOM   5506 C  C   . SER E 5 8   ? 117.073 127.762 169.304 1.00 67.97  ? 7   SER F C   1 
ATOM   5507 O  O   . SER E 5 8   ? 117.444 126.711 168.767 1.00 67.97  ? 7   SER F O   1 
ATOM   5508 C  CB  . SER E 5 8   ? 115.016 128.903 168.442 1.00 67.97  ? 7   SER F CB  1 
ATOM   5509 O  OG  . SER E 5 8   ? 114.506 130.007 167.716 1.00 67.97  ? 7   SER F OG  1 
ATOM   5510 N  N   . PRO E 5 9   ? 117.136 127.933 170.637 1.00 68.06  ? 8   PRO F N   1 
ATOM   5511 C  CA  . PRO E 5 9   ? 116.843 129.172 171.369 1.00 68.06  ? 8   PRO F CA  1 
ATOM   5512 C  C   . PRO E 5 9   ? 117.983 130.180 171.271 1.00 68.06  ? 8   PRO F C   1 
ATOM   5513 O  O   . PRO E 5 9   ? 119.126 129.782 171.059 1.00 68.06  ? 8   PRO F O   1 
ATOM   5514 C  CB  . PRO E 5 9   ? 116.658 128.698 172.819 1.00 68.06  ? 8   PRO F CB  1 
ATOM   5515 C  CG  . PRO E 5 9   ? 116.671 127.192 172.769 1.00 68.06  ? 8   PRO F CG  1 
ATOM   5516 C  CD  . PRO E 5 9   ? 117.447 126.827 171.553 1.00 68.06  ? 8   PRO F CD  1 
ATOM   5517 N  N   . SER E 5 10  ? 117.670 131.471 171.412 1.00 67.41  ? 9   SER F N   1 
ATOM   5518 C  CA  . SER E 5 10  ? 118.714 132.488 171.356 1.00 67.41  ? 9   SER F CA  1 
ATOM   5519 C  C   . SER E 5 10  ? 119.705 132.327 172.503 1.00 67.41  ? 9   SER F C   1 
ATOM   5520 O  O   . SER E 5 10  ? 120.919 132.447 172.303 1.00 67.41  ? 9   SER F O   1 
ATOM   5521 C  CB  . SER E 5 10  ? 118.089 133.882 171.375 1.00 67.41  ? 9   SER F CB  1 
ATOM   5522 O  OG  . SER E 5 10  ? 117.319 134.107 170.207 1.00 67.41  ? 9   SER F OG  1 
ATOM   5523 N  N   . PHE E 5 11  ? 119.208 132.055 173.707 1.00 70.39  ? 10  PHE F N   1 
ATOM   5524 C  CA  . PHE E 5 11  ? 120.046 131.816 174.874 1.00 70.39  ? 10  PHE F CA  1 
ATOM   5525 C  C   . PHE E 5 11  ? 119.474 130.646 175.658 1.00 70.39  ? 10  PHE F C   1 
ATOM   5526 O  O   . PHE E 5 11  ? 118.252 130.513 175.776 1.00 70.39  ? 10  PHE F O   1 
ATOM   5527 C  CB  . PHE E 5 11  ? 120.135 133.061 175.762 1.00 70.39  ? 10  PHE F CB  1 
ATOM   5528 C  CG  . PHE E 5 11  ? 120.627 134.284 175.043 1.00 70.39  ? 10  PHE F CG  1 
ATOM   5529 C  CD1 . PHE E 5 11  ? 121.948 134.382 174.638 1.00 70.39  ? 10  PHE F CD1 1 
ATOM   5530 C  CD2 . PHE E 5 11  ? 119.768 135.336 174.770 1.00 70.39  ? 10  PHE F CD2 1 
ATOM   5531 C  CE1 . PHE E 5 11  ? 122.404 135.506 173.976 1.00 70.39  ? 10  PHE F CE1 1 
ATOM   5532 C  CE2 . PHE E 5 11  ? 120.218 136.463 174.108 1.00 70.39  ? 10  PHE F CE2 1 
ATOM   5533 C  CZ  . PHE E 5 11  ? 121.538 136.548 173.710 1.00 70.39  ? 10  PHE F CZ  1 
ATOM   5534 N  N   . LEU E 5 12  ? 120.355 129.801 176.191 1.00 71.58  ? 11  LEU F N   1 
ATOM   5535 C  CA  . LEU E 5 12  ? 119.942 128.626 176.946 1.00 71.58  ? 11  LEU F CA  1 
ATOM   5536 C  C   . LEU E 5 12  ? 120.999 128.302 177.989 1.00 71.58  ? 11  LEU F C   1 
ATOM   5537 O  O   . LEU E 5 12  ? 122.190 128.251 177.673 1.00 71.58  ? 11  LEU F O   1 
ATOM   5538 C  CB  . LEU E 5 12  ? 119.724 127.422 176.022 1.00 71.58  ? 11  LEU F CB  1 
ATOM   5539 C  CG  . LEU E 5 12  ? 118.928 126.252 176.601 1.00 71.58  ? 11  LEU F CG  1 
ATOM   5540 C  CD1 . LEU E 5 12  ? 117.560 126.715 177.076 1.00 71.58  ? 11  LEU F CD1 1 
ATOM   5541 C  CD2 . LEU E 5 12  ? 118.795 125.134 175.578 1.00 71.58  ? 11  LEU F CD2 1 
ATOM   5542 N  N   . SER E 5 13  ? 120.562 128.083 179.226 1.00 71.00  ? 12  SER F N   1 
ATOM   5543 C  CA  . SER E 5 13  ? 121.454 127.737 180.327 1.00 71.00  ? 12  SER F CA  1 
ATOM   5544 C  C   . SER E 5 13  ? 121.210 126.281 180.705 1.00 71.00  ? 12  SER F C   1 
ATOM   5545 O  O   . SER E 5 13  ? 120.088 125.905 181.061 1.00 71.00  ? 12  SER F O   1 
ATOM   5546 C  CB  . SER E 5 13  ? 121.228 128.662 181.520 1.00 71.00  ? 12  SER F CB  1 
ATOM   5547 O  OG  . SER E 5 13  ? 121.756 129.954 181.273 1.00 71.00  ? 12  SER F OG  1 
ATOM   5548 N  N   . ALA E 5 14  ? 122.258 125.465 180.628 1.00 70.35  ? 13  ALA F N   1 
ATOM   5549 C  CA  . ALA E 5 14  ? 122.173 124.051 180.955 1.00 70.35  ? 13  ALA F CA  1 
ATOM   5550 C  C   . ALA E 5 14  ? 123.419 123.620 181.713 1.00 70.35  ? 13  ALA F C   1 
ATOM   5551 O  O   . ALA E 5 14  ? 124.511 124.154 181.500 1.00 70.35  ? 13  ALA F O   1 
ATOM   5552 C  CB  . ALA E 5 14  ? 122.005 123.192 179.698 1.00 70.35  ? 13  ALA F CB  1 
ATOM   5553 N  N   . SER E 5 15  ? 123.244 122.645 182.600 1.00 68.59  ? 14  SER F N   1 
ATOM   5554 C  CA  . SER E 5 15  ? 124.347 122.126 183.392 1.00 68.59  ? 14  SER F CA  1 
ATOM   5555 C  C   . SER E 5 15  ? 125.213 121.193 182.547 1.00 68.59  ? 14  SER F C   1 
ATOM   5556 O  O   . SER E 5 15  ? 124.948 120.947 181.367 1.00 68.59  ? 14  SER F O   1 
ATOM   5557 C  CB  . SER E 5 15  ? 123.818 121.413 184.634 1.00 68.59  ? 14  SER F CB  1 
ATOM   5558 O  OG  . SER E 5 15  ? 124.869 120.786 185.348 1.00 68.59  ? 14  SER F OG  1 
ATOM   5559 N  N   . VAL E 5 16  ? 126.269 120.664 183.165 1.00 67.33  ? 15  VAL F N   1 
ATOM   5560 C  CA  . VAL E 5 16  ? 127.197 119.791 182.457 1.00 67.33  ? 15  VAL F CA  1 
ATOM   5561 C  C   . VAL E 5 16  ? 126.556 118.427 182.235 1.00 67.33  ? 15  VAL F C   1 
ATOM   5562 O  O   . VAL E 5 16  ? 125.835 117.907 183.098 1.00 67.33  ? 15  VAL F O   1 
ATOM   5563 C  CB  . VAL E 5 16  ? 128.515 119.671 183.241 1.00 67.33  ? 15  VAL F CB  1 
ATOM   5564 C  CG1 . VAL E 5 16  ? 129.531 118.844 182.469 1.00 67.33  ? 15  VAL F CG1 1 
ATOM   5565 C  CG2 . VAL E 5 16  ? 129.072 121.050 183.553 1.00 67.33  ? 15  VAL F CG2 1 
ATOM   5566 N  N   . GLY E 5 17  ? 126.816 117.841 181.070 1.00 67.94  ? 16  GLY F N   1 
ATOM   5567 C  CA  . GLY E 5 17  ? 126.338 116.502 180.767 1.00 67.94  ? 16  GLY F CA  1 
ATOM   5568 C  C   . GLY E 5 17  ? 124.834 116.356 180.681 1.00 67.94  ? 16  GLY F C   1 
ATOM   5569 O  O   . GLY E 5 17  ? 124.275 115.419 181.264 1.00 67.94  ? 16  GLY F O   1 
ATOM   5570 N  N   . ASP E 5 18  ? 124.164 117.256 179.970 1.00 66.59  ? 17  ASP F N   1 
ATOM   5571 C  CA  . ASP E 5 18  ? 122.717 117.217 179.824 1.00 66.59  ? 17  ASP F CA  1 
ATOM   5572 C  C   . ASP E 5 18  ? 122.334 117.218 178.348 1.00 66.59  ? 17  ASP F C   1 
ATOM   5573 O  O   . ASP E 5 18  ? 123.111 117.614 177.476 1.00 66.59  ? 17  ASP F O   1 
ATOM   5574 C  CB  . ASP E 5 18  ? 122.059 118.401 180.544 1.00 66.59  ? 17  ASP F CB  1 
ATOM   5575 C  CG  . ASP E 5 18  ? 122.164 118.295 182.052 1.00 66.59  ? 17  ASP F CG  1 
ATOM   5576 O  OD1 . ASP E 5 18  ? 122.217 117.159 182.568 1.00 66.59  ? 17  ASP F OD1 1 
ATOM   5577 O  OD2 . ASP E 5 18  ? 122.193 119.349 182.721 1.00 66.59  ? 17  ASP F OD2 1 
ATOM   5578 N  N   . ARG E 5 19  ? 121.114 116.757 178.081 1.00 68.28  ? 18  ARG F N   1 
ATOM   5579 C  CA  . ARG E 5 19  ? 120.548 116.790 176.736 1.00 68.28  ? 18  ARG F CA  1 
ATOM   5580 C  C   . ARG E 5 19  ? 120.369 118.241 176.307 1.00 68.28  ? 18  ARG F C   1 
ATOM   5581 O  O   . ARG E 5 19  ? 119.569 118.972 176.900 1.00 68.28  ? 18  ARG F O   1 
ATOM   5582 C  CB  . ARG E 5 19  ? 119.205 116.064 176.712 1.00 68.28  ? 18  ARG F CB  1 
ATOM   5583 C  CG  . ARG E 5 19  ? 119.242 114.562 176.948 1.00 68.28  ? 18  ARG F CG  1 
ATOM   5584 C  CD  . ARG E 5 19  ? 119.715 113.790 175.727 1.00 68.28  ? 18  ARG F CD  1 
ATOM   5585 N  NE  . ARG E 5 19  ? 121.108 113.377 175.833 1.00 68.28  ? 18  ARG F NE  1 
ATOM   5586 C  CZ  . ARG E 5 19  ? 121.808 112.849 174.839 1.00 68.28  ? 18  ARG F CZ  1 
ATOM   5587 N  NH1 . ARG E 5 19  ? 121.285 112.688 173.634 1.00 68.28  ? 18  ARG F NH1 1 
ATOM   5588 N  NH2 . ARG E 5 19  ? 123.060 112.462 175.062 1.00 68.28  ? 18  ARG F NH2 1 
ATOM   5589 N  N   . ILE E 5 20  ? 121.104 118.669 175.284 1.00 64.89  ? 19  ILE F N   1 
ATOM   5590 C  CA  . ILE E 5 20  ? 120.959 120.009 174.727 1.00 64.89  ? 19  ILE F CA  1 
ATOM   5591 C  C   . ILE E 5 20  ? 120.847 119.910 173.211 1.00 64.89  ? 19  ILE F C   1 
ATOM   5592 O  O   . ILE E 5 20  ? 121.650 119.227 172.558 1.00 64.89  ? 19  ILE F O   1 
ATOM   5593 C  CB  . ILE E 5 20  ? 122.108 120.942 175.159 1.00 64.89  ? 19  ILE F CB  1 
ATOM   5594 C  CG1 . ILE E 5 20  ? 123.471 120.382 174.761 1.00 64.89  ? 19  ILE F CG1 1 
ATOM   5595 C  CG2 . ILE E 5 20  ? 122.054 121.202 176.656 1.00 64.89  ? 19  ILE F CG2 1 
ATOM   5596 C  CD1 . ILE E 5 20  ? 124.611 121.346 175.017 1.00 64.89  ? 19  ILE F CD1 1 
ATOM   5597 N  N   . THR E 5 21  ? 119.824 120.569 172.663 1.00 63.39  ? 20  THR F N   1 
ATOM   5598 C  CA  . THR E 5 21  ? 119.528 120.566 171.239 1.00 63.39  ? 20  THR F CA  1 
ATOM   5599 C  C   . THR E 5 21  ? 119.198 121.980 170.777 1.00 63.39  ? 20  THR F C   1 
ATOM   5600 O  O   . THR E 5 21  ? 118.691 122.803 171.544 1.00 63.39  ? 20  THR F O   1 
ATOM   5601 C  CB  . THR E 5 21  ? 118.360 119.621 170.907 1.00 63.39  ? 20  THR F CB  1 
ATOM   5602 O  OG1 . THR E 5 21  ? 118.097 119.654 169.499 1.00 63.39  ? 20  THR F OG1 1 
ATOM   5603 C  CG2 . THR E 5 21  ? 117.107 120.026 171.667 1.00 63.39  ? 20  THR F CG2 1 
ATOM   5604 N  N   . ILE E 5 22  ? 119.506 122.253 169.511 1.00 63.61  ? 21  ILE F N   1 
ATOM   5605 C  CA  . ILE E 5 22  ? 119.323 123.569 168.904 1.00 63.61  ? 21  ILE F CA  1 
ATOM   5606 C  C   . ILE E 5 22  ? 118.703 123.383 167.526 1.00 63.61  ? 21  ILE F C   1 
ATOM   5607 O  O   . ILE E 5 22  ? 119.082 122.470 166.784 1.00 63.61  ? 21  ILE F O   1 
ATOM   5608 C  CB  . ILE E 5 22  ? 120.657 124.338 168.810 1.00 63.61  ? 21  ILE F CB  1 
ATOM   5609 C  CG1 . ILE E 5 22  ? 121.287 124.475 170.194 1.00 63.61  ? 21  ILE F CG1 1 
ATOM   5610 C  CG2 . ILE E 5 22  ? 120.455 125.708 168.180 1.00 63.61  ? 21  ILE F CG2 1 
ATOM   5611 C  CD1 . ILE E 5 22  ? 122.711 124.920 170.161 1.00 63.61  ? 21  ILE F CD1 1 
ATOM   5612 N  N   . THR E 5 23  ? 117.750 124.251 167.182 1.00 66.72  ? 22  THR F N   1 
ATOM   5613 C  CA  . THR E 5 23  ? 116.973 124.118 165.956 1.00 66.72  ? 22  THR F CA  1 
ATOM   5614 C  C   . THR E 5 23  ? 117.204 125.328 165.061 1.00 66.72  ? 22  THR F C   1 
ATOM   5615 O  O   . THR E 5 23  ? 116.968 126.465 165.476 1.00 66.72  ? 22  THR F O   1 
ATOM   5616 C  CB  . THR E 5 23  ? 115.483 123.972 166.273 1.00 66.72  ? 22  THR F CB  1 
ATOM   5617 O  OG1 . THR E 5 23  ? 115.291 122.891 167.194 1.00 66.72  ? 22  THR F OG1 1 
ATOM   5618 C  CG2 . THR E 5 23  ? 114.693 123.704 165.006 1.00 66.72  ? 22  THR F CG2 1 
ATOM   5619 N  N   . CYS E 5 24  ? 117.635 125.077 163.828 1.00 68.14  ? 23  CYS F N   1 
ATOM   5620 C  CA  . CYS E 5 24  ? 117.790 126.107 162.809 1.00 68.14  ? 23  CYS F CA  1 
ATOM   5621 C  C   . CYS E 5 24  ? 116.703 125.923 161.758 1.00 68.14  ? 23  CYS F C   1 
ATOM   5622 O  O   . CYS E 5 24  ? 116.484 124.807 161.274 1.00 68.14  ? 23  CYS F O   1 
ATOM   5623 C  CB  . CYS E 5 24  ? 119.179 126.043 162.166 1.00 68.14  ? 23  CYS F CB  1 
ATOM   5624 S  SG  . CYS E 5 24  ? 119.506 127.310 160.913 1.00 68.14  ? 23  CYS F SG  1 
ATOM   5625 N  N   . ARG E 5 25  ? 116.025 127.013 161.406 1.00 73.14  ? 24  ARG F N   1 
ATOM   5626 C  CA  . ARG E 5 25  ? 114.868 126.970 160.528 1.00 73.14  ? 24  ARG F CA  1 
ATOM   5627 C  C   . ARG E 5 25  ? 115.064 127.915 159.352 1.00 73.14  ? 24  ARG F C   1 
ATOM   5628 O  O   . ARG E 5 25  ? 115.658 128.992 159.486 1.00 73.14  ? 24  ARG F O   1 
ATOM   5629 C  CB  . ARG E 5 25  ? 113.590 127.344 161.288 1.00 73.14  ? 24  ARG F CB  1 
ATOM   5630 C  CG  . ARG E 5 25  ? 112.910 126.168 161.969 1.00 73.14  ? 24  ARG F CG  1 
ATOM   5631 C  CD  . ARG E 5 25  ? 111.423 126.412 162.152 1.00 73.14  ? 24  ARG F CD  1 
ATOM   5632 N  NE  . ARG E 5 25  ? 110.907 125.742 163.339 1.00 73.14  ? 24  ARG F NE  1 
ATOM   5633 C  CZ  . ARG E 5 25  ? 110.428 124.506 163.353 1.00 73.14  ? 24  ARG F CZ  1 
ATOM   5634 N  NH1 . ARG E 5 25  ? 110.389 123.767 162.257 1.00 73.14  ? 24  ARG F NH1 1 
ATOM   5635 N  NH2 . ARG E 5 25  ? 109.978 123.997 164.497 1.00 73.14  ? 24  ARG F NH2 1 
ATOM   5636 N  N   . ALA E 5 26  ? 114.546 127.499 158.197 1.00 75.69  ? 25  ALA F N   1 
ATOM   5637 C  CA  . ALA E 5 26  ? 114.628 128.264 156.964 1.00 75.69  ? 25  ALA F CA  1 
ATOM   5638 C  C   . ALA E 5 26  ? 113.233 128.457 156.389 1.00 75.69  ? 25  ALA F C   1 
ATOM   5639 O  O   . ALA E 5 26  ? 112.314 127.684 156.677 1.00 75.69  ? 25  ALA F O   1 
ATOM   5640 C  CB  . ALA E 5 26  ? 115.529 127.573 155.931 1.00 75.69  ? 25  ALA F CB  1 
ATOM   5641 N  N   . SER E 5 27  ? 113.082 129.506 155.577 1.00 75.24  ? 26  SER F N   1 
ATOM   5642 C  CA  . SER E 5 27  ? 111.778 129.812 154.995 1.00 75.24  ? 26  SER F CA  1 
ATOM   5643 C  C   . SER E 5 27  ? 111.307 128.700 154.065 1.00 75.24  ? 26  SER F C   1 
ATOM   5644 O  O   . SER E 5 27  ? 110.132 128.315 154.092 1.00 75.24  ? 26  SER F O   1 
ATOM   5645 C  CB  . SER E 5 27  ? 111.838 131.144 154.249 1.00 75.24  ? 26  SER F CB  1 
ATOM   5646 O  OG  . SER E 5 27  ? 113.004 131.228 153.449 1.00 75.24  ? 26  SER F OG  1 
ATOM   5647 N  N   . GLN E 5 28  ? 112.205 128.173 153.238 1.00 76.06  ? 27  GLN F N   1 
ATOM   5648 C  CA  . GLN E 5 28  ? 111.879 127.110 152.301 1.00 76.06  ? 27  GLN F CA  1 
ATOM   5649 C  C   . GLN E 5 28  ? 112.918 126.001 152.390 1.00 76.06  ? 27  GLN F C   1 
ATOM   5650 O  O   . GLN E 5 28  ? 114.009 126.183 152.939 1.00 76.06  ? 27  GLN F O   1 
ATOM   5651 C  CB  . GLN E 5 28  ? 111.795 127.639 150.863 1.00 76.06  ? 27  GLN F CB  1 
ATOM   5652 C  CG  . GLN E 5 28  ? 110.512 128.393 150.554 1.00 76.06  ? 27  GLN F CG  1 
ATOM   5653 C  CD  . GLN E 5 28  ? 110.535 129.046 149.187 1.00 76.06  ? 27  GLN F CD  1 
ATOM   5654 O  OE1 . GLN E 5 28  ? 111.381 128.731 148.349 1.00 76.06  ? 27  GLN F OE1 1 
ATOM   5655 N  NE2 . GLN E 5 28  ? 109.602 129.961 148.953 1.00 76.06  ? 27  GLN F NE2 1 
ATOM   5656 N  N   . GLY E 5 29  ? 112.560 124.839 151.846 1.00 74.58  ? 28  GLY F N   1 
ATOM   5657 C  CA  . GLY E 5 29  ? 113.431 123.680 151.871 1.00 74.58  ? 28  GLY F CA  1 
ATOM   5658 C  C   . GLY E 5 29  ? 114.768 123.905 151.198 1.00 74.58  ? 28  GLY F C   1 
ATOM   5659 O  O   . GLY E 5 29  ? 114.829 124.372 150.056 1.00 74.58  ? 28  GLY F O   1 
ATOM   5660 N  N   . ILE E 5 30  ? 115.850 123.574 151.900 1.00 66.51  ? 29  ILE F N   1 
ATOM   5661 C  CA  . ILE E 5 30  ? 117.205 123.752 151.397 1.00 66.51  ? 29  ILE F CA  1 
ATOM   5662 C  C   . ILE E 5 30  ? 117.917 122.419 151.211 1.00 66.51  ? 29  ILE F C   1 
ATOM   5663 O  O   . ILE E 5 30  ? 119.148 122.391 151.096 1.00 66.51  ? 29  ILE F O   1 
ATOM   5664 C  CB  . ILE E 5 30  ? 118.019 124.681 152.311 1.00 66.51  ? 29  ILE F CB  1 
ATOM   5665 C  CG1 . ILE E 5 30  ? 118.157 124.069 153.705 1.00 66.51  ? 29  ILE F CG1 1 
ATOM   5666 C  CG2 . ILE E 5 30  ? 117.363 126.050 152.394 1.00 66.51  ? 29  ILE F CG2 1 
ATOM   5667 C  CD1 . ILE E 5 30  ? 118.999 124.895 154.653 1.00 66.51  ? 29  ILE F CD1 1 
ATOM   5668 N  N   . ASP E 5 31  ? 117.175 121.318 151.175 1.00 68.54  ? 30  ASP F N   1 
ATOM   5669 C  CA  . ASP E 5 31  ? 117.728 119.956 151.051 1.00 68.54  ? 30  ASP F CA  1 
ATOM   5670 C  C   . ASP E 5 31  ? 118.668 119.735 152.241 1.00 68.54  ? 30  ASP F C   1 
ATOM   5671 O  O   . ASP E 5 31  ? 118.335 120.127 153.370 1.00 68.54  ? 30  ASP F O   1 
ATOM   5672 C  CB  . ASP E 5 31  ? 118.361 119.771 149.684 1.00 68.54  ? 30  ASP F CB  1 
ATOM   5673 C  CG  . ASP E 5 31  ? 117.334 119.558 148.590 1.00 68.54  ? 30  ASP F CG  1 
ATOM   5674 O  OD1 . ASP E 5 31  ? 116.143 119.375 148.918 1.00 68.54  ? 30  ASP F OD1 1 
ATOM   5675 O  OD2 . ASP E 5 31  ? 117.717 119.572 147.401 1.00 68.54  ? 30  ASP F OD2 1 
ATOM   5676 N  N   . GLY E 5 32  ? 119.829 119.120 152.035 1.00 61.78  ? 31  GLY F N   1 
ATOM   5677 C  CA  . GLY E 5 32  ? 120.766 118.902 153.118 1.00 61.78  ? 31  GLY F CA  1 
ATOM   5678 C  C   . GLY E 5 32  ? 121.884 119.921 153.137 1.00 61.78  ? 31  GLY F C   1 
ATOM   5679 O  O   . GLY E 5 32  ? 122.922 119.704 153.769 1.00 61.78  ? 31  GLY F O   1 
ATOM   5680 N  N   . TYR E 5 33  ? 121.683 121.043 152.445 1.00 58.18  ? 32  TYR F N   1 
ATOM   5681 C  CA  . TYR E 5 33  ? 122.717 122.068 152.298 1.00 58.18  ? 32  TYR F CA  1 
ATOM   5682 C  C   . TYR E 5 33  ? 122.722 122.976 153.528 1.00 58.18  ? 32  TYR F C   1 
ATOM   5683 O  O   . TYR E 5 33  ? 122.224 124.104 153.522 1.00 58.18  ? 32  TYR F O   1 
ATOM   5684 C  CB  . TYR E 5 33  ? 122.496 122.864 151.020 1.00 58.18  ? 32  TYR F CB  1 
ATOM   5685 C  CG  . TYR E 5 33  ? 122.686 122.064 149.752 1.00 58.18  ? 32  TYR F CG  1 
ATOM   5686 C  CD1 . TYR E 5 33  ? 121.652 121.301 149.228 1.00 58.18  ? 32  TYR F CD1 1 
ATOM   5687 C  CD2 . TYR E 5 33  ? 123.897 122.075 149.077 1.00 58.18  ? 32  TYR F CD2 1 
ATOM   5688 C  CE1 . TYR E 5 33  ? 121.821 120.570 148.070 1.00 58.18  ? 32  TYR F CE1 1 
ATOM   5689 C  CE2 . TYR E 5 33  ? 124.074 121.348 147.918 1.00 58.18  ? 32  TYR F CE2 1 
ATOM   5690 C  CZ  . TYR E 5 33  ? 123.034 120.598 147.419 1.00 58.18  ? 32  TYR F CZ  1 
ATOM   5691 O  OH  . TYR E 5 33  ? 123.206 119.871 146.264 1.00 58.18  ? 32  TYR F OH  1 
ATOM   5692 N  N   . LEU E 5 34  ? 123.306 122.459 154.607 1.00 59.81  ? 33  LEU F N   1 
ATOM   5693 C  CA  . LEU E 5 34  ? 123.440 123.226 155.837 1.00 59.81  ? 33  LEU F CA  1 
ATOM   5694 C  C   . LEU E 5 34  ? 124.612 122.678 156.637 1.00 59.81  ? 33  LEU F C   1 
ATOM   5695 O  O   . LEU E 5 34  ? 124.859 121.469 156.645 1.00 59.81  ? 33  LEU F O   1 
ATOM   5696 C  CB  . LEU E 5 34  ? 122.144 123.188 156.662 1.00 59.81  ? 33  LEU F CB  1 
ATOM   5697 C  CG  . LEU E 5 34  ? 122.020 124.078 157.904 1.00 59.81  ? 33  LEU F CG  1 
ATOM   5698 C  CD1 . LEU E 5 34  ? 120.563 124.409 158.157 1.00 59.81  ? 33  LEU F CD1 1 
ATOM   5699 C  CD2 . LEU E 5 34  ? 122.609 123.414 159.141 1.00 59.81  ? 33  LEU F CD2 1 
ATOM   5700 N  N   . ALA E 5 35  ? 125.327 123.578 157.305 1.00 57.41  ? 34  ALA F N   1 
ATOM   5701 C  CA  . ALA E 5 35  ? 126.475 123.224 158.127 1.00 57.41  ? 34  ALA F CA  1 
ATOM   5702 C  C   . ALA E 5 35  ? 126.373 123.923 159.475 1.00 57.41  ? 34  ALA F C   1 
ATOM   5703 O  O   . ALA E 5 35  ? 125.692 124.942 159.610 1.00 57.41  ? 34  ALA F O   1 
ATOM   5704 C  CB  . ALA E 5 35  ? 127.795 123.596 157.443 1.00 57.41  ? 34  ALA F CB  1 
ATOM   5705 N  N   . TRP E 5 36  ? 127.053 123.368 160.475 1.00 56.29  ? 35  TRP F N   1 
ATOM   5706 C  CA  . TRP E 5 36  ? 127.035 123.908 161.829 1.00 56.29  ? 35  TRP F CA  1 
ATOM   5707 C  C   . TRP E 5 36  ? 128.445 124.283 162.261 1.00 56.29  ? 35  TRP F C   1 
ATOM   5708 O  O   . TRP E 5 36  ? 129.387 123.509 162.062 1.00 56.29  ? 35  TRP F O   1 
ATOM   5709 C  CB  . TRP E 5 36  ? 126.435 122.904 162.812 1.00 56.29  ? 35  TRP F CB  1 
ATOM   5710 C  CG  . TRP E 5 36  ? 124.944 122.847 162.779 1.00 56.29  ? 35  TRP F CG  1 
ATOM   5711 C  CD1 . TRP E 5 36  ? 124.173 122.005 162.037 1.00 56.29  ? 35  TRP F CD1 1 
ATOM   5712 C  CD2 . TRP E 5 36  ? 124.039 123.660 163.533 1.00 56.29  ? 35  TRP F CD2 1 
ATOM   5713 N  NE1 . TRP E 5 36  ? 122.842 122.245 162.276 1.00 56.29  ? 35  TRP F NE1 1 
ATOM   5714 C  CE2 . TRP E 5 36  ? 122.733 123.258 163.192 1.00 56.29  ? 35  TRP F CE2 1 
ATOM   5715 C  CE3 . TRP E 5 36  ? 124.205 124.692 164.462 1.00 56.29  ? 35  TRP F CE3 1 
ATOM   5716 C  CZ2 . TRP E 5 36  ? 121.601 123.850 163.745 1.00 56.29  ? 35  TRP F CZ2 1 
ATOM   5717 C  CZ3 . TRP E 5 36  ? 123.080 125.278 165.010 1.00 56.29  ? 35  TRP F CZ3 1 
ATOM   5718 C  CH2 . TRP E 5 36  ? 121.795 124.856 164.650 1.00 56.29  ? 35  TRP F CH2 1 
ATOM   5719 N  N   . TYR E 5 37  ? 128.582 125.465 162.857 1.00 56.59  ? 36  TYR F N   1 
ATOM   5720 C  CA  . TYR E 5 37  ? 129.871 125.995 163.277 1.00 56.59  ? 36  TYR F CA  1 
ATOM   5721 C  C   . TYR E 5 37  ? 129.834 126.353 164.756 1.00 56.59  ? 36  TYR F C   1 
ATOM   5722 O  O   . TYR E 5 37  ? 128.861 126.943 165.237 1.00 56.59  ? 36  TYR F O   1 
ATOM   5723 C  CB  . TYR E 5 37  ? 130.258 127.230 162.457 1.00 56.59  ? 36  TYR F CB  1 
ATOM   5724 C  CG  . TYR E 5 37  ? 130.572 126.940 161.008 1.00 56.59  ? 36  TYR F CG  1 
ATOM   5725 C  CD1 . TYR E 5 37  ? 129.580 126.525 160.132 1.00 56.59  ? 36  TYR F CD1 1 
ATOM   5726 C  CD2 . TYR E 5 37  ? 131.862 127.081 160.516 1.00 56.59  ? 36  TYR F CD2 1 
ATOM   5727 C  CE1 . TYR E 5 37  ? 129.861 126.258 158.813 1.00 56.59  ? 36  TYR F CE1 1 
ATOM   5728 C  CE2 . TYR E 5 37  ? 132.152 126.816 159.193 1.00 56.59  ? 36  TYR F CE2 1 
ATOM   5729 C  CZ  . TYR E 5 37  ? 131.147 126.405 158.347 1.00 56.59  ? 36  TYR F CZ  1 
ATOM   5730 O  OH  . TYR E 5 37  ? 131.425 126.139 157.027 1.00 56.59  ? 36  TYR F OH  1 
ATOM   5731 N  N   . GLN E 5 38  ? 130.903 125.997 165.466 1.00 56.39  ? 37  GLN F N   1 
ATOM   5732 C  CA  . GLN E 5 38  ? 131.073 126.301 166.881 1.00 56.39  ? 37  GLN F CA  1 
ATOM   5733 C  C   . GLN E 5 38  ? 132.205 127.301 167.053 1.00 56.39  ? 37  GLN F C   1 
ATOM   5734 O  O   . GLN E 5 38  ? 133.299 127.100 166.518 1.00 56.39  ? 37  GLN F O   1 
ATOM   5735 C  CB  . GLN E 5 38  ? 131.378 125.038 167.687 1.00 56.39  ? 37  GLN F CB  1 
ATOM   5736 C  CG  . GLN E 5 38  ? 131.678 125.303 169.152 1.00 56.39  ? 37  GLN F CG  1 
ATOM   5737 C  CD  . GLN E 5 38  ? 131.849 124.032 169.954 1.00 56.39  ? 37  GLN F CD  1 
ATOM   5738 O  OE1 . GLN E 5 38  ? 131.056 123.735 170.846 1.00 56.39  ? 37  GLN F OE1 1 
ATOM   5739 N  NE2 . GLN E 5 38  ? 132.892 123.272 169.643 1.00 56.39  ? 37  GLN F NE2 1 
ATOM   5740 N  N   . GLN E 5 39  ? 131.946 128.366 167.809 1.00 59.29  ? 38  GLN F N   1 
ATOM   5741 C  CA  . GLN E 5 39  ? 132.939 129.399 168.085 1.00 59.29  ? 38  GLN F CA  1 
ATOM   5742 C  C   . GLN E 5 39  ? 133.005 129.623 169.589 1.00 59.29  ? 38  GLN F C   1 
ATOM   5743 O  O   . GLN E 5 39  ? 132.024 130.059 170.199 1.00 59.29  ? 38  GLN F O   1 
ATOM   5744 C  CB  . GLN E 5 39  ? 132.599 130.701 167.359 1.00 59.29  ? 38  GLN F CB  1 
ATOM   5745 C  CG  . GLN E 5 39  ? 133.390 131.900 167.851 1.00 59.29  ? 38  GLN F CG  1 
ATOM   5746 C  CD  . GLN E 5 39  ? 132.936 133.198 167.219 1.00 59.29  ? 38  GLN F CD  1 
ATOM   5747 O  OE1 . GLN E 5 39  ? 131.812 133.304 166.731 1.00 59.29  ? 38  GLN F OE1 1 
ATOM   5748 N  NE2 . GLN E 5 39  ? 133.810 134.196 167.228 1.00 59.29  ? 38  GLN F NE2 1 
ATOM   5749 N  N   . ARG E 5 40  ? 134.158 129.331 170.184 1.00 64.85  ? 39  ARG F N   1 
ATOM   5750 C  CA  . ARG E 5 40  ? 134.339 129.573 171.604 1.00 64.85  ? 39  ARG F CA  1 
ATOM   5751 C  C   . ARG E 5 40  ? 134.554 131.063 171.868 1.00 64.85  ? 39  ARG F C   1 
ATOM   5752 O  O   . ARG E 5 40  ? 134.963 131.805 170.971 1.00 64.85  ? 39  ARG F O   1 
ATOM   5753 C  CB  . ARG E 5 40  ? 135.523 128.774 172.139 1.00 64.85  ? 39  ARG F CB  1 
ATOM   5754 C  CG  . ARG E 5 40  ? 135.131 127.491 172.852 1.00 64.85  ? 39  ARG F CG  1 
ATOM   5755 C  CD  . ARG E 5 40  ? 136.350 126.647 173.175 1.00 64.85  ? 39  ARG F CD  1 
ATOM   5756 N  NE  . ARG E 5 40  ? 136.988 126.131 171.971 1.00 64.85  ? 39  ARG F NE  1 
ATOM   5757 C  CZ  . ARG E 5 40  ? 138.294 126.161 171.744 1.00 64.85  ? 39  ARG F CZ  1 
ATOM   5758 N  NH1 . ARG E 5 40  ? 139.137 126.677 172.623 1.00 64.85  ? 39  ARG F NH1 1 
ATOM   5759 N  NH2 . ARG E 5 40  ? 138.766 125.661 170.606 1.00 64.85  ? 39  ARG F NH2 1 
ATOM   5760 N  N   . PRO E 5 41  ? 134.244 131.527 173.080 1.00 63.22  ? 40  PRO F N   1 
ATOM   5761 C  CA  . PRO E 5 41  ? 134.545 132.916 173.442 1.00 63.22  ? 40  PRO F CA  1 
ATOM   5762 C  C   . PRO E 5 41  ? 135.981 133.290 173.105 1.00 63.22  ? 40  PRO F C   1 
ATOM   5763 O  O   . PRO E 5 41  ? 136.934 132.728 173.649 1.00 63.22  ? 40  PRO F O   1 
ATOM   5764 C  CB  . PRO E 5 41  ? 134.306 132.942 174.955 1.00 63.22  ? 40  PRO F CB  1 
ATOM   5765 C  CG  . PRO E 5 41  ? 133.421 131.735 175.249 1.00 63.22  ? 40  PRO F CG  1 
ATOM   5766 C  CD  . PRO E 5 41  ? 133.225 130.957 173.974 1.00 63.22  ? 40  PRO F CD  1 
ATOM   5767 N  N   . GLY E 5 42  ? 136.127 134.254 172.199 1.00 63.53  ? 41  GLY F N   1 
ATOM   5768 C  CA  . GLY E 5 42  ? 137.442 134.691 171.780 1.00 63.53  ? 41  GLY F CA  1 
ATOM   5769 C  C   . GLY E 5 42  ? 138.248 133.657 171.032 1.00 63.53  ? 41  GLY F C   1 
ATOM   5770 O  O   . GLY E 5 42  ? 139.468 133.596 171.202 1.00 63.53  ? 41  GLY F O   1 
ATOM   5771 N  N   . LYS E 5 43  ? 137.603 132.840 170.203 1.00 64.24  ? 42  LYS F N   1 
ATOM   5772 C  CA  . LYS E 5 43  ? 138.280 131.816 169.424 1.00 64.24  ? 42  LYS F CA  1 
ATOM   5773 C  C   . LYS E 5 43  ? 137.716 131.790 168.012 1.00 64.24  ? 42  LYS F C   1 
ATOM   5774 O  O   . LYS E 5 43  ? 136.589 132.224 167.762 1.00 64.24  ? 42  LYS F O   1 
ATOM   5775 C  CB  . LYS E 5 43  ? 138.141 130.428 170.067 1.00 64.24  ? 42  LYS F CB  1 
ATOM   5776 C  CG  . LYS E 5 43  ? 138.826 130.288 171.417 1.00 64.24  ? 42  LYS F CG  1 
ATOM   5777 C  CD  . LYS E 5 43  ? 140.338 130.364 171.277 1.00 64.24  ? 42  LYS F CD  1 
ATOM   5778 C  CE  . LYS E 5 43  ? 140.893 129.118 170.607 1.00 64.24  ? 42  LYS F CE  1 
ATOM   5779 N  NZ  . LYS E 5 43  ? 142.380 129.135 170.543 1.00 64.24  ? 42  LYS F NZ  1 
ATOM   5780 N  N   . ALA E 5 44  ? 138.519 131.280 167.086 1.00 59.74  ? 43  ALA F N   1 
ATOM   5781 C  CA  . ALA E 5 44  ? 138.062 131.137 165.714 1.00 59.74  ? 43  ALA F CA  1 
ATOM   5782 C  C   . ALA E 5 44  ? 137.033 130.013 165.622 1.00 59.74  ? 43  ALA F C   1 
ATOM   5783 O  O   . ALA E 5 44  ? 137.207 128.960 166.243 1.00 59.74  ? 43  ALA F O   1 
ATOM   5784 C  CB  . ALA E 5 44  ? 139.236 130.848 164.782 1.00 59.74  ? 43  ALA F CB  1 
ATOM   5785 N  N   . PRO E 5 45  ? 135.954 130.205 164.868 1.00 58.99  ? 44  PRO F N   1 
ATOM   5786 C  CA  . PRO E 5 45  ? 134.942 129.150 164.756 1.00 58.99  ? 44  PRO F CA  1 
ATOM   5787 C  C   . PRO E 5 45  ? 135.481 127.924 164.036 1.00 58.99  ? 44  PRO F C   1 
ATOM   5788 O  O   . PRO E 5 45  ? 136.324 128.017 163.140 1.00 58.99  ? 44  PRO F O   1 
ATOM   5789 C  CB  . PRO E 5 45  ? 133.817 129.816 163.956 1.00 58.99  ? 44  PRO F CB  1 
ATOM   5790 C  CG  . PRO E 5 45  ? 134.471 130.931 163.228 1.00 58.99  ? 44  PRO F CG  1 
ATOM   5791 C  CD  . PRO E 5 45  ? 135.602 131.403 164.089 1.00 58.99  ? 44  PRO F CD  1 
ATOM   5792 N  N   . ASN E 5 46  ? 134.979 126.762 164.446 1.00 58.28  ? 45  ASN F N   1 
ATOM   5793 C  CA  . ASN E 5 46  ? 135.371 125.481 163.876 1.00 58.28  ? 45  ASN F CA  1 
ATOM   5794 C  C   . ASN E 5 46  ? 134.133 124.728 163.413 1.00 58.28  ? 45  ASN F C   1 
ATOM   5795 O  O   . ASN E 5 46  ? 133.102 124.731 164.092 1.00 58.28  ? 45  ASN F O   1 
ATOM   5796 C  CB  . ASN E 5 46  ? 136.149 124.635 164.889 1.00 58.28  ? 45  ASN F CB  1 
ATOM   5797 C  CG  . ASN E 5 46  ? 137.330 125.376 165.483 1.00 58.28  ? 45  ASN F CG  1 
ATOM   5798 O  OD1 . ASN E 5 46  ? 137.918 126.247 164.842 1.00 58.28  ? 45  ASN F OD1 1 
ATOM   5799 N  ND2 . ASN E 5 46  ? 137.684 125.033 166.716 1.00 58.28  ? 45  ASN F ND2 1 
ATOM   5800 N  N   . LEU E 5 47  ? 134.243 124.082 162.255 1.00 55.51  ? 46  LEU F N   1 
ATOM   5801 C  CA  . LEU E 5 47  ? 133.113 123.361 161.687 1.00 55.51  ? 46  LEU F CA  1 
ATOM   5802 C  C   . LEU E 5 47  ? 132.835 122.094 162.484 1.00 55.51  ? 46  LEU F C   1 
ATOM   5803 O  O   . LEU E 5 47  ? 133.746 121.307 162.756 1.00 55.51  ? 46  LEU F O   1 
ATOM   5804 C  CB  . LEU E 5 47  ? 133.393 123.016 160.225 1.00 55.51  ? 46  LEU F CB  1 
ATOM   5805 C  CG  . LEU E 5 47  ? 132.351 122.172 159.492 1.00 55.51  ? 46  LEU F CG  1 
ATOM   5806 C  CD1 . LEU E 5 47  ? 131.043 122.926 159.356 1.00 55.51  ? 46  LEU F CD1 1 
ATOM   5807 C  CD2 . LEU E 5 47  ? 132.872 121.755 158.128 1.00 55.51  ? 46  LEU F CD2 1 
ATOM   5808 N  N   . LEU E 5 48  ? 131.572 121.897 162.860 1.00 56.68  ? 47  LEU F N   1 
ATOM   5809 C  CA  . LEU E 5 48  ? 131.174 120.693 163.582 1.00 56.68  ? 47  LEU F CA  1 
ATOM   5810 C  C   . LEU E 5 48  ? 130.646 119.621 162.633 1.00 56.68  ? 47  LEU F C   1 
ATOM   5811 O  O   . LEU E 5 48  ? 131.212 118.527 162.544 1.00 56.68  ? 47  LEU F O   1 
ATOM   5812 C  CB  . LEU E 5 48  ? 130.119 121.033 164.641 1.00 56.68  ? 47  LEU F CB  1 
ATOM   5813 C  CG  . LEU E 5 48  ? 130.556 121.925 165.802 1.00 56.68  ? 47  LEU F CG  1 
ATOM   5814 C  CD1 . LEU E 5 48  ? 129.436 122.049 166.823 1.00 56.68  ? 47  LEU F CD1 1 
ATOM   5815 C  CD2 . LEU E 5 48  ? 131.821 121.384 166.449 1.00 56.68  ? 47  LEU F CD2 1 
ATOM   5816 N  N   . ILE E 5 49  ? 129.563 119.922 161.920 1.00 54.37  ? 48  ILE F N   1 
ATOM   5817 C  CA  . ILE E 5 49  ? 128.969 118.995 160.968 1.00 54.37  ? 48  ILE F CA  1 
ATOM   5818 C  C   . ILE E 5 49  ? 128.698 119.727 159.662 1.00 54.37  ? 48  ILE F C   1 
ATOM   5819 O  O   . ILE E 5 49  ? 128.442 120.937 159.642 1.00 54.37  ? 48  ILE F O   1 
ATOM   5820 C  CB  . ILE E 5 49  ? 127.667 118.347 161.501 1.00 54.37  ? 48  ILE F CB  1 
ATOM   5821 C  CG1 . ILE E 5 49  ? 126.503 119.337 161.444 1.00 54.37  ? 48  ILE F CG1 1 
ATOM   5822 C  CG2 . ILE E 5 49  ? 127.854 117.819 162.915 1.00 54.37  ? 48  ILE F CG2 1 
ATOM   5823 C  CD1 . ILE E 5 49  ? 125.148 118.685 161.556 1.00 54.37  ? 48  ILE F CD1 1 
ATOM   5824 N  N   . TYR E 5 50  ? 128.769 118.981 158.563 1.00 53.55  ? 49  TYR F N   1 
ATOM   5825 C  CA  . TYR E 5 50  ? 128.380 119.455 157.245 1.00 53.55  ? 49  TYR F CA  1 
ATOM   5826 C  C   . TYR E 5 50  ? 127.422 118.445 156.629 1.00 53.55  ? 49  TYR F C   1 
ATOM   5827 O  O   . TYR E 5 50  ? 127.378 117.277 157.027 1.00 53.55  ? 49  TYR F O   1 
ATOM   5828 C  CB  . TYR E 5 50  ? 129.601 119.688 156.342 1.00 53.55  ? 49  TYR F CB  1 
ATOM   5829 C  CG  . TYR E 5 50  ? 130.386 118.443 155.994 1.00 53.55  ? 49  TYR F CG  1 
ATOM   5830 C  CD1 . TYR E 5 50  ? 130.056 117.674 154.887 1.00 53.55  ? 49  TYR F CD1 1 
ATOM   5831 C  CD2 . TYR E 5 50  ? 131.469 118.047 156.765 1.00 53.55  ? 49  TYR F CD2 1 
ATOM   5832 C  CE1 . TYR E 5 50  ? 130.775 116.540 154.565 1.00 53.55  ? 49  TYR F CE1 1 
ATOM   5833 C  CE2 . TYR E 5 50  ? 132.195 116.915 156.451 1.00 53.55  ? 49  TYR F CE2 1 
ATOM   5834 C  CZ  . TYR E 5 50  ? 131.844 116.166 155.350 1.00 53.55  ? 49  TYR F CZ  1 
ATOM   5835 O  OH  . TYR E 5 50  ? 132.564 115.037 155.033 1.00 53.55  ? 49  TYR F OH  1 
ATOM   5836 N  N   . ALA E 5 51  ? 126.636 118.916 155.661 1.00 53.59  ? 50  ALA F N   1 
ATOM   5837 C  CA  . ALA E 5 51  ? 125.568 118.141 155.030 1.00 53.59  ? 50  ALA F CA  1 
ATOM   5838 C  C   . ALA E 5 51  ? 124.514 117.689 156.035 1.00 53.59  ? 50  ALA F C   1 
ATOM   5839 O  O   . ALA E 5 51  ? 123.761 116.747 155.765 1.00 53.59  ? 50  ALA F O   1 
ATOM   5840 C  CB  . ALA E 5 51  ? 126.123 116.933 154.264 1.00 53.59  ? 50  ALA F CB  1 
ATOM   5841 N  N   . ALA E 5 52  ? 124.485 118.330 157.206 1.00 56.65  ? 51  ALA F N   1 
ATOM   5842 C  CA  . ALA E 5 52  ? 123.447 118.174 158.223 1.00 56.65  ? 51  ALA F CA  1 
ATOM   5843 C  C   . ALA E 5 52  ? 123.515 116.827 158.932 1.00 56.65  ? 51  ALA F C   1 
ATOM   5844 O  O   . ALA E 5 52  ? 122.784 116.599 159.902 1.00 56.65  ? 51  ALA F O   1 
ATOM   5845 C  CB  . ALA E 5 52  ? 122.056 118.377 157.616 1.00 56.65  ? 51  ALA F CB  1 
ATOM   5846 N  N   . SER E 5 53  ? 124.378 115.926 158.465 1.00 54.72  ? 52  SER F N   1 
ATOM   5847 C  CA  . SER E 5 53  ? 124.561 114.644 159.140 1.00 54.72  ? 52  SER F CA  1 
ATOM   5848 C  C   . SER E 5 53  ? 126.004 114.175 159.228 1.00 54.72  ? 52  SER F C   1 
ATOM   5849 O  O   . SER E 5 53  ? 126.283 113.274 160.025 1.00 54.72  ? 52  SER F O   1 
ATOM   5850 C  CB  . SER E 5 53  ? 123.732 113.555 158.449 1.00 54.72  ? 52  SER F CB  1 
ATOM   5851 O  OG  . SER E 5 53  ? 122.391 113.572 158.905 1.00 54.72  ? 52  SER F OG  1 
ATOM   5852 N  N   . LEU E 5 54  ? 126.933 114.741 158.463 1.00 53.62  ? 53  LEU F N   1 
ATOM   5853 C  CA  . LEU E 5 54  ? 128.290 114.218 158.409 1.00 53.62  ? 53  LEU F CA  1 
ATOM   5854 C  C   . LEU E 5 54  ? 129.190 114.966 159.382 1.00 53.62  ? 53  LEU F C   1 
ATOM   5855 O  O   . LEU E 5 54  ? 129.294 116.195 159.328 1.00 53.62  ? 53  LEU F O   1 
ATOM   5856 C  CB  . LEU E 5 54  ? 128.844 114.323 156.988 1.00 53.62  ? 53  LEU F CB  1 
ATOM   5857 C  CG  . LEU E 5 54  ? 128.138 113.502 155.907 1.00 53.62  ? 53  LEU F CG  1 
ATOM   5858 C  CD1 . LEU E 5 54  ? 129.045 113.317 154.703 1.00 53.62  ? 53  LEU F CD1 1 
ATOM   5859 C  CD2 . LEU E 5 54  ? 127.687 112.154 156.453 1.00 53.62  ? 53  LEU F CD2 1 
ATOM   5860 N  N   . LEU E 5 55  ? 129.843 114.221 160.268 1.00 54.01  ? 54  LEU F N   1 
ATOM   5861 C  CA  . LEU E 5 55  ? 130.766 114.798 161.233 1.00 54.01  ? 54  LEU F CA  1 
ATOM   5862 C  C   . LEU E 5 55  ? 132.119 115.047 160.582 1.00 54.01  ? 54  LEU F C   1 
ATOM   5863 O  O   . LEU E 5 55  ? 132.493 114.371 159.620 1.00 54.01  ? 54  LEU F O   1 
ATOM   5864 C  CB  . LEU E 5 55  ? 130.935 113.878 162.444 1.00 54.01  ? 54  LEU F CB  1 
ATOM   5865 C  CG  . LEU E 5 55  ? 129.961 114.011 163.618 1.00 54.01  ? 54  LEU F CG  1 
ATOM   5866 C  CD1 . LEU E 5 55  ? 128.513 113.851 163.177 1.00 54.01  ? 54  LEU F CD1 1 
ATOM   5867 C  CD2 . LEU E 5 55  ? 130.304 113.005 164.705 1.00 54.01  ? 54  LEU F CD2 1 
ATOM   5868 N  N   . GLN E 5 56  ? 132.847 116.023 161.112 1.00 57.08  ? 55  GLN F N   1 
ATOM   5869 C  CA  . GLN E 5 56  ? 134.193 116.294 160.634 1.00 57.08  ? 55  GLN F CA  1 
ATOM   5870 C  C   . GLN E 5 56  ? 135.156 115.231 161.155 1.00 57.08  ? 55  GLN F C   1 
ATOM   5871 O  O   . GLN E 5 56  ? 134.848 114.485 162.088 1.00 57.08  ? 55  GLN F O   1 
ATOM   5872 C  CB  . GLN E 5 56  ? 134.641 117.690 161.071 1.00 57.08  ? 55  GLN F CB  1 
ATOM   5873 C  CG  . GLN E 5 56  ? 135.811 118.263 160.285 1.00 57.08  ? 55  GLN F CG  1 
ATOM   5874 C  CD  . GLN E 5 56  ? 135.385 118.888 158.972 1.00 57.08  ? 55  GLN F CD  1 
ATOM   5875 O  OE1 . GLN E 5 56  ? 134.230 118.778 158.563 1.00 57.08  ? 55  GLN F OE1 1 
ATOM   5876 N  NE2 . GLN E 5 56  ? 136.321 119.550 158.301 1.00 57.08  ? 55  GLN F NE2 1 
ATOM   5877 N  N   . SER E 5 57  ? 136.331 115.157 160.527 1.00 60.58  ? 56  SER F N   1 
ATOM   5878 C  CA  . SER E 5 57  ? 137.297 114.118 160.874 1.00 60.58  ? 56  SER F CA  1 
ATOM   5879 C  C   . SER E 5 57  ? 137.791 114.268 162.309 1.00 60.58  ? 56  SER F C   1 
ATOM   5880 O  O   . SER E 5 57  ? 137.916 113.278 163.040 1.00 60.58  ? 56  SER F O   1 
ATOM   5881 C  CB  . SER E 5 57  ? 138.470 114.151 159.894 1.00 60.58  ? 56  SER F CB  1 
ATOM   5882 O  OG  . SER E 5 57  ? 138.021 114.020 158.556 1.00 60.58  ? 56  SER F OG  1 
ATOM   5883 N  N   . GLY E 5 58  ? 138.079 115.501 162.734 1.00 60.30  ? 57  GLY F N   1 
ATOM   5884 C  CA  . GLY E 5 58  ? 138.706 115.700 164.029 1.00 60.30  ? 57  GLY F CA  1 
ATOM   5885 C  C   . GLY E 5 58  ? 137.759 115.995 165.171 1.00 60.30  ? 57  GLY F C   1 
ATOM   5886 O  O   . GLY E 5 58  ? 138.176 115.936 166.333 1.00 60.30  ? 57  GLY F O   1 
ATOM   5887 N  N   . VAL E 5 59  ? 136.500 116.309 164.878 1.00 59.51  ? 58  VAL F N   1 
ATOM   5888 C  CA  . VAL E 5 59  ? 135.540 116.682 165.915 1.00 59.51  ? 58  VAL F CA  1 
ATOM   5889 C  C   . VAL E 5 59  ? 135.166 115.455 166.740 1.00 59.51  ? 58  VAL F C   1 
ATOM   5890 O  O   . VAL E 5 59  ? 135.150 114.333 166.212 1.00 59.51  ? 58  VAL F O   1 
ATOM   5891 C  CB  . VAL E 5 59  ? 134.290 117.342 165.310 1.00 59.51  ? 58  VAL F CB  1 
ATOM   5892 C  CG1 . VAL E 5 59  ? 134.668 118.626 164.589 1.00 59.51  ? 58  VAL F CG1 1 
ATOM   5893 C  CG2 . VAL E 5 59  ? 133.577 116.384 164.373 1.00 59.51  ? 58  VAL F CG2 1 
ATOM   5894 N  N   . PRO E 5 60  ? 134.884 115.616 168.038 1.00 57.69  ? 59  PRO F N   1 
ATOM   5895 C  CA  . PRO E 5 60  ? 134.462 114.470 168.856 1.00 57.69  ? 59  PRO F CA  1 
ATOM   5896 C  C   . PRO E 5 60  ? 133.181 113.826 168.350 1.00 57.69  ? 59  PRO F C   1 
ATOM   5897 O  O   . PRO E 5 60  ? 132.460 114.413 167.539 1.00 57.69  ? 59  PRO F O   1 
ATOM   5898 C  CB  . PRO E 5 60  ? 134.267 115.088 170.246 1.00 57.69  ? 59  PRO F CB  1 
ATOM   5899 C  CG  . PRO E 5 60  ? 135.145 116.296 170.244 1.00 57.69  ? 59  PRO F CG  1 
ATOM   5900 C  CD  . PRO E 5 60  ? 135.074 116.833 168.846 1.00 57.69  ? 59  PRO F CD  1 
ATOM   5901 N  N   . SER E 5 61  ? 132.886 112.618 168.827 1.00 59.46  ? 60  SER F N   1 
ATOM   5902 C  CA  . SER E 5 61  ? 131.747 111.846 168.350 1.00 59.46  ? 60  SER F CA  1 
ATOM   5903 C  C   . SER E 5 61  ? 130.482 112.103 169.158 1.00 59.46  ? 60  SER F C   1 
ATOM   5904 O  O   . SER E 5 61  ? 129.479 111.410 168.958 1.00 59.46  ? 60  SER F O   1 
ATOM   5905 C  CB  . SER E 5 61  ? 132.081 110.352 168.358 1.00 59.46  ? 60  SER F CB  1 
ATOM   5906 O  OG  . SER E 5 61  ? 132.276 109.874 169.678 1.00 59.46  ? 60  SER F OG  1 
ATOM   5907 N  N   . ARG E 5 62  ? 130.500 113.081 170.058 1.00 59.33  ? 61  ARG F N   1 
ATOM   5908 C  CA  . ARG E 5 62  ? 129.350 113.406 170.889 1.00 59.33  ? 61  ARG F CA  1 
ATOM   5909 C  C   . ARG E 5 62  ? 128.480 114.513 170.302 1.00 59.33  ? 61  ARG F C   1 
ATOM   5910 O  O   . ARG E 5 62  ? 127.516 114.934 170.948 1.00 59.33  ? 61  ARG F O   1 
ATOM   5911 C  CB  . ARG E 5 62  ? 129.821 113.786 172.294 1.00 59.33  ? 61  ARG F CB  1 
ATOM   5912 C  CG  . ARG E 5 62  ? 130.675 115.036 172.343 1.00 59.33  ? 61  ARG F CG  1 
ATOM   5913 C  CD  . ARG E 5 62  ? 131.206 115.279 173.744 1.00 59.33  ? 61  ARG F CD  1 
ATOM   5914 N  NE  . ARG E 5 62  ? 132.611 115.666 173.734 1.00 59.33  ? 61  ARG F NE  1 
ATOM   5915 C  CZ  . ARG E 5 62  ? 133.042 116.917 173.667 1.00 59.33  ? 61  ARG F CZ  1 
ATOM   5916 N  NH1 . ARG E 5 62  ? 132.199 117.934 173.601 1.00 59.33  ? 61  ARG F NH1 1 
ATOM   5917 N  NH2 . ARG E 5 62  ? 134.350 117.154 173.659 1.00 59.33  ? 61  ARG F NH2 1 
ATOM   5918 N  N   . PHE E 5 63  ? 128.797 114.992 169.101 1.00 58.74  ? 62  PHE F N   1 
ATOM   5919 C  CA  . PHE E 5 63  ? 127.986 115.974 168.393 1.00 58.74  ? 62  PHE F CA  1 
ATOM   5920 C  C   . PHE E 5 63  ? 127.214 115.261 167.293 1.00 58.74  ? 62  PHE F C   1 
ATOM   5921 O  O   . PHE E 5 63  ? 127.811 114.548 166.479 1.00 58.74  ? 62  PHE F O   1 
ATOM   5922 C  CB  . PHE E 5 63  ? 128.859 117.080 167.794 1.00 58.74  ? 62  PHE F CB  1 
ATOM   5923 C  CG  . PHE E 5 63  ? 129.541 117.942 168.818 1.00 58.74  ? 62  PHE F CG  1 
ATOM   5924 C  CD1 . PHE E 5 63  ? 128.979 118.142 170.067 1.00 58.74  ? 62  PHE F CD1 1 
ATOM   5925 C  CD2 . PHE E 5 63  ? 130.752 118.547 168.531 1.00 58.74  ? 62  PHE F CD2 1 
ATOM   5926 C  CE1 . PHE E 5 63  ? 129.612 118.935 171.007 1.00 58.74  ? 62  PHE F CE1 1 
ATOM   5927 C  CE2 . PHE E 5 63  ? 131.389 119.338 169.467 1.00 58.74  ? 62  PHE F CE2 1 
ATOM   5928 C  CZ  . PHE E 5 63  ? 130.818 119.533 170.705 1.00 58.74  ? 62  PHE F CZ  1 
ATOM   5929 N  N   . SER E 5 64  ? 125.895 115.450 167.261 1.00 61.93  ? 63  SER F N   1 
ATOM   5930 C  CA  . SER E 5 64  ? 125.043 114.781 166.286 1.00 61.93  ? 63  SER F CA  1 
ATOM   5931 C  C   . SER E 5 64  ? 124.191 115.818 165.573 1.00 61.93  ? 63  SER F C   1 
ATOM   5932 O  O   . SER E 5 64  ? 123.795 116.821 166.176 1.00 61.93  ? 63  SER F O   1 
ATOM   5933 C  CB  . SER E 5 64  ? 124.157 113.728 166.958 1.00 61.93  ? 63  SER F CB  1 
ATOM   5934 O  OG  . SER E 5 64  ? 123.224 114.331 167.836 1.00 61.93  ? 63  SER F OG  1 
ATOM   5935 N  N   . GLY E 5 65  ? 123.917 115.580 164.293 1.00 61.47  ? 64  GLY F N   1 
ATOM   5936 C  CA  . GLY E 5 65  ? 123.068 116.448 163.499 1.00 61.47  ? 64  GLY F CA  1 
ATOM   5937 C  C   . GLY E 5 65  ? 121.996 115.647 162.786 1.00 61.47  ? 64  GLY F C   1 
ATOM   5938 O  O   . GLY E 5 65  ? 122.189 114.471 162.470 1.00 61.47  ? 64  GLY F O   1 
ATOM   5939 N  N   . SER E 5 66  ? 120.860 116.291 162.533 1.00 64.69  ? 65  SER F N   1 
ATOM   5940 C  CA  . SER E 5 66  ? 119.756 115.631 161.853 1.00 64.69  ? 65  SER F CA  1 
ATOM   5941 C  C   . SER E 5 66  ? 118.874 116.687 161.204 1.00 64.69  ? 65  SER F C   1 
ATOM   5942 O  O   . SER E 5 66  ? 118.951 117.873 161.531 1.00 64.69  ? 65  SER F O   1 
ATOM   5943 C  CB  . SER E 5 66  ? 118.940 114.763 162.817 1.00 64.69  ? 65  SER F CB  1 
ATOM   5944 O  OG  . SER E 5 66  ? 118.272 115.560 163.779 1.00 64.69  ? 65  SER F OG  1 
ATOM   5945 N  N   . GLY E 5 67  ? 118.034 116.236 160.278 1.00 70.62  ? 66  GLY F N   1 
ATOM   5946 C  CA  . GLY E 5 67  ? 117.104 117.128 159.616 1.00 70.62  ? 66  GLY F CA  1 
ATOM   5947 C  C   . GLY E 5 67  ? 117.232 117.130 158.107 1.00 70.62  ? 66  GLY F C   1 
ATOM   5948 O  O   . GLY E 5 67  ? 118.332 116.977 157.567 1.00 70.62  ? 66  GLY F O   1 
ATOM   5949 N  N   . TYR E 5 68  ? 116.108 117.304 157.417 1.00 74.02  ? 67  TYR F N   1 
ATOM   5950 C  CA  . TYR E 5 68  ? 116.095 117.335 155.957 1.00 74.02  ? 67  TYR F CA  1 
ATOM   5951 C  C   . TYR E 5 68  ? 114.898 118.168 155.523 1.00 74.02  ? 67  TYR F C   1 
ATOM   5952 O  O   . TYR E 5 68  ? 113.760 117.693 155.578 1.00 74.02  ? 67  TYR F O   1 
ATOM   5953 C  CB  . TYR E 5 68  ? 116.027 115.925 155.375 1.00 74.02  ? 67  TYR F CB  1 
ATOM   5954 C  CG  . TYR E 5 68  ? 116.407 115.843 153.914 1.00 74.02  ? 67  TYR F CG  1 
ATOM   5955 C  CD1 . TYR E 5 68  ? 115.475 116.100 152.917 1.00 74.02  ? 67  TYR F CD1 1 
ATOM   5956 C  CD2 . TYR E 5 68  ? 117.699 115.507 153.531 1.00 74.02  ? 67  TYR F CD2 1 
ATOM   5957 C  CE1 . TYR E 5 68  ? 115.819 116.026 151.581 1.00 74.02  ? 67  TYR F CE1 1 
ATOM   5958 C  CE2 . TYR E 5 68  ? 118.052 115.430 152.198 1.00 74.02  ? 67  TYR F CE2 1 
ATOM   5959 C  CZ  . TYR E 5 68  ? 117.108 115.690 151.228 1.00 74.02  ? 67  TYR F CZ  1 
ATOM   5960 O  OH  . TYR E 5 68  ? 117.455 115.615 149.899 1.00 74.02  ? 67  TYR F OH  1 
ATOM   5961 N  N   . GLY E 5 69  ? 115.153 119.401 155.094 1.00 74.07  ? 68  GLY F N   1 
ATOM   5962 C  CA  . GLY E 5 69  ? 114.083 120.288 154.685 1.00 74.07  ? 68  GLY F CA  1 
ATOM   5963 C  C   . GLY E 5 69  ? 114.219 121.690 155.241 1.00 74.07  ? 68  GLY F C   1 
ATOM   5964 O  O   . GLY E 5 69  ? 115.204 122.381 154.965 1.00 74.07  ? 68  GLY F O   1 
ATOM   5965 N  N   . THR E 5 70  ? 113.231 122.125 156.023 1.00 73.68  ? 69  THR F N   1 
ATOM   5966 C  CA  . THR E 5 70  ? 113.236 123.465 156.593 1.00 73.68  ? 69  THR F CA  1 
ATOM   5967 C  C   . THR E 5 70  ? 113.715 123.509 158.037 1.00 73.68  ? 69  THR F C   1 
ATOM   5968 O  O   . THR E 5 70  ? 114.093 124.585 158.512 1.00 73.68  ? 69  THR F O   1 
ATOM   5969 C  CB  . THR E 5 70  ? 111.833 124.082 156.520 1.00 73.68  ? 69  THR F CB  1 
ATOM   5970 O  OG1 . THR E 5 70  ? 110.902 123.240 157.211 1.00 73.68  ? 69  THR F OG1 1 
ATOM   5971 C  CG2 . THR E 5 70  ? 111.394 124.233 155.073 1.00 73.68  ? 69  THR F CG2 1 
ATOM   5972 N  N   . GLU E 5 71  ? 113.710 122.381 158.742 1.00 71.96  ? 70  GLU F N   1 
ATOM   5973 C  CA  . GLU E 5 71  ? 114.090 122.324 160.147 1.00 71.96  ? 70  GLU F CA  1 
ATOM   5974 C  C   . GLU E 5 71  ? 115.297 121.413 160.313 1.00 71.96  ? 70  GLU F C   1 
ATOM   5975 O  O   . GLU E 5 71  ? 115.293 120.277 159.827 1.00 71.96  ? 70  GLU F O   1 
ATOM   5976 C  CB  . GLU E 5 71  ? 112.924 121.825 161.005 1.00 71.96  ? 70  GLU F CB  1 
ATOM   5977 C  CG  . GLU E 5 71  ? 113.262 121.657 162.474 1.00 71.96  ? 70  GLU F CG  1 
ATOM   5978 C  CD  . GLU E 5 71  ? 112.138 121.012 163.262 1.00 71.96  ? 70  GLU F CD  1 
ATOM   5979 O  OE1 . GLU E 5 71  ? 110.971 121.119 162.831 1.00 71.96  ? 70  GLU F OE1 1 
ATOM   5980 O  OE2 . GLU E 5 71  ? 112.423 120.401 164.313 1.00 71.96  ? 70  GLU F OE2 1 
ATOM   5981 N  N   . PHE E 5 72  ? 116.326 121.911 160.997 1.00 67.08  ? 71  PHE F N   1 
ATOM   5982 C  CA  . PHE E 5 72  ? 117.533 121.147 161.269 1.00 67.08  ? 71  PHE F CA  1 
ATOM   5983 C  C   . PHE E 5 72  ? 117.819 121.182 162.762 1.00 67.08  ? 71  PHE F C   1 
ATOM   5984 O  O   . PHE E 5 72  ? 117.672 122.220 163.411 1.00 67.08  ? 71  PHE F O   1 
ATOM   5985 C  CB  . PHE E 5 72  ? 118.742 121.699 160.497 1.00 67.08  ? 71  PHE F CB  1 
ATOM   5986 C  CG  . PHE E 5 72  ? 118.620 121.582 159.003 1.00 67.08  ? 71  PHE F CG  1 
ATOM   5987 C  CD1 . PHE E 5 72  ? 117.746 122.392 158.297 1.00 67.08  ? 71  PHE F CD1 1 
ATOM   5988 C  CD2 . PHE E 5 72  ? 119.388 120.668 158.305 1.00 67.08  ? 71  PHE F CD2 1 
ATOM   5989 C  CE1 . PHE E 5 72  ? 117.638 122.288 156.925 1.00 67.08  ? 71  PHE F CE1 1 
ATOM   5990 C  CE2 . PHE E 5 72  ? 119.283 120.558 156.933 1.00 67.08  ? 71  PHE F CE2 1 
ATOM   5991 C  CZ  . PHE E 5 72  ? 118.407 121.369 156.242 1.00 67.08  ? 71  PHE F CZ  1 
ATOM   5992 N  N   . THR E 5 73  ? 118.231 120.039 163.307 1.00 64.70  ? 72  THR F N   1 
ATOM   5993 C  CA  . THR E 5 73  ? 118.486 119.908 164.733 1.00 64.70  ? 72  THR F CA  1 
ATOM   5994 C  C   . THR E 5 73  ? 119.921 119.462 164.968 1.00 64.70  ? 72  THR F C   1 
ATOM   5995 O  O   . THR E 5 73  ? 120.450 118.602 164.258 1.00 64.70  ? 72  THR F O   1 
ATOM   5996 C  CB  . THR E 5 73  ? 117.524 118.907 165.392 1.00 64.70  ? 72  THR F CB  1 
ATOM   5997 O  OG1 . THR E 5 73  ? 117.796 117.587 164.904 1.00 64.70  ? 72  THR F OG1 1 
ATOM   5998 C  CG2 . THR E 5 73  ? 116.080 119.268 165.083 1.00 64.70  ? 72  THR F CG2 1 
ATOM   5999 N  N   . LEU E 5 74  ? 120.552 120.068 165.971 1.00 59.87  ? 73  LEU F N   1 
ATOM   6000 C  CA  . LEU E 5 74  ? 121.874 119.657 166.425 1.00 59.87  ? 73  LEU F CA  1 
ATOM   6001 C  C   . LEU E 5 74  ? 121.799 119.327 167.906 1.00 59.87  ? 73  LEU F C   1 
ATOM   6002 O  O   . LEU E 5 74  ? 121.242 120.102 168.689 1.00 59.87  ? 73  LEU F O   1 
ATOM   6003 C  CB  . LEU E 5 74  ? 122.925 120.744 166.167 1.00 59.87  ? 73  LEU F CB  1 
ATOM   6004 C  CG  . LEU E 5 74  ? 124.358 120.421 166.602 1.00 59.87  ? 73  LEU F CG  1 
ATOM   6005 C  CD1 . LEU E 5 74  ? 125.354 120.941 165.592 1.00 59.87  ? 73  LEU F CD1 1 
ATOM   6006 C  CD2 . LEU E 5 74  ? 124.654 121.026 167.959 1.00 59.87  ? 73  LEU F CD2 1 
ATOM   6007 N  N   . THR E 5 75  ? 122.370 118.187 168.288 1.00 60.12  ? 74  THR F N   1 
ATOM   6008 C  CA  . THR E 5 75  ? 122.298 117.693 169.656 1.00 60.12  ? 74  THR F CA  1 
ATOM   6009 C  C   . THR E 5 75  ? 123.700 117.397 170.165 1.00 60.12  ? 74  THR F C   1 
ATOM   6010 O  O   . THR E 5 75  ? 124.493 116.744 169.477 1.00 60.12  ? 74  THR F O   1 
ATOM   6011 C  CB  . THR E 5 75  ? 121.428 116.433 169.739 1.00 60.12  ? 74  THR F CB  1 
ATOM   6012 O  OG1 . THR E 5 75  ? 120.073 116.764 169.414 1.00 60.12  ? 74  THR F OG1 1 
ATOM   6013 C  CG2 . THR E 5 75  ? 121.477 115.834 171.136 1.00 60.12  ? 74  THR F CG2 1 
ATOM   6014 N  N   . ILE E 5 76  ? 124.007 117.876 171.366 1.00 59.22  ? 75  ILE F N   1 
ATOM   6015 C  CA  . ILE E 5 76  ? 125.257 117.525 172.031 1.00 59.22  ? 75  ILE F CA  1 
ATOM   6016 C  C   . ILE E 5 76  ? 124.974 116.376 172.991 1.00 59.22  ? 75  ILE F C   1 
ATOM   6017 O  O   . ILE E 5 76  ? 124.111 116.487 173.868 1.00 59.22  ? 75  ILE F O   1 
ATOM   6018 C  CB  . ILE E 5 76  ? 125.871 118.726 172.765 1.00 59.22  ? 75  ILE F CB  1 
ATOM   6019 C  CG1 . ILE E 5 76  ? 126.268 119.829 171.779 1.00 59.22  ? 75  ILE F CG1 1 
ATOM   6020 C  CG2 . ILE E 5 76  ? 127.075 118.289 173.578 1.00 59.22  ? 75  ILE F CG2 1 
ATOM   6021 C  CD1 . ILE E 5 76  ? 125.184 120.845 171.498 1.00 59.22  ? 75  ILE F CD1 1 
ATOM   6022 N  N   . SER E 5 77  ? 125.698 115.266 172.816 1.00 62.08  ? 76  SER F N   1 
ATOM   6023 C  CA  . SER E 5 77  ? 125.427 114.070 173.607 1.00 62.08  ? 76  SER F CA  1 
ATOM   6024 C  C   . SER E 5 77  ? 125.654 114.305 175.095 1.00 62.08  ? 76  SER F C   1 
ATOM   6025 O  O   . SER E 5 77  ? 124.829 113.893 175.918 1.00 62.08  ? 76  SER F O   1 
ATOM   6026 C  CB  . SER E 5 77  ? 126.291 112.907 173.120 1.00 62.08  ? 76  SER F CB  1 
ATOM   6027 O  OG  . SER E 5 77  ? 126.140 112.707 171.725 1.00 62.08  ? 76  SER F OG  1 
ATOM   6028 N  N   . SER E 5 78  ? 126.755 114.961 175.458 1.00 63.23  ? 77  SER F N   1 
ATOM   6029 C  CA  . SER E 5 78  ? 127.044 115.262 176.859 1.00 63.23  ? 77  SER F CA  1 
ATOM   6030 C  C   . SER E 5 78  ? 127.834 116.567 176.885 1.00 63.23  ? 77  SER F C   1 
ATOM   6031 O  O   . SER E 5 78  ? 128.899 116.662 176.267 1.00 63.23  ? 77  SER F O   1 
ATOM   6032 C  CB  . SER E 5 78  ? 127.812 114.126 177.521 1.00 63.23  ? 77  SER F CB  1 
ATOM   6033 O  OG  . SER E 5 78  ? 128.255 114.491 178.817 1.00 63.23  ? 77  SER F OG  1 
ATOM   6034 N  N   . LEU E 5 79  ? 127.306 117.562 177.593 1.00 66.32  ? 78  LEU F N   1 
ATOM   6035 C  CA  . LEU E 5 79  ? 127.969 118.856 177.664 1.00 66.32  ? 78  LEU F CA  1 
ATOM   6036 C  C   . LEU E 5 79  ? 129.293 118.725 178.405 1.00 66.32  ? 78  LEU F C   1 
ATOM   6037 O  O   . LEU E 5 79  ? 129.433 117.920 179.329 1.00 66.32  ? 78  LEU F O   1 
ATOM   6038 C  CB  . LEU E 5 79  ? 127.056 119.878 178.348 1.00 66.32  ? 78  LEU F CB  1 
ATOM   6039 C  CG  . LEU E 5 79  ? 127.450 121.359 178.389 1.00 66.32  ? 78  LEU F CG  1 
ATOM   6040 C  CD1 . LEU E 5 79  ? 126.197 122.210 178.485 1.00 66.32  ? 78  LEU F CD1 1 
ATOM   6041 C  CD2 . LEU E 5 79  ? 128.378 121.679 179.551 1.00 66.32  ? 78  LEU F CD2 1 
ATOM   6042 N  N   . GLN E 5 80  ? 130.266 119.518 177.988 1.00 66.78  ? 79  GLN F N   1 
ATOM   6043 C  CA  . GLN E 5 80  ? 131.619 119.493 178.515 1.00 66.78  ? 79  GLN F CA  1 
ATOM   6044 C  C   . GLN E 5 80  ? 132.064 120.917 178.804 1.00 66.78  ? 79  GLN F C   1 
ATOM   6045 O  O   . GLN E 5 80  ? 131.467 121.875 178.301 1.00 66.78  ? 79  GLN F O   1 
ATOM   6046 C  CB  . GLN E 5 80  ? 132.583 118.829 177.519 1.00 66.78  ? 79  GLN F CB  1 
ATOM   6047 C  CG  . GLN E 5 80  ? 132.310 117.353 177.284 1.00 66.78  ? 79  GLN F CG  1 
ATOM   6048 C  CD  . GLN E 5 80  ? 132.577 116.508 178.512 1.00 66.78  ? 79  GLN F CD  1 
ATOM   6049 O  OE1 . GLN E 5 80  ? 131.656 115.954 179.111 1.00 66.78  ? 79  GLN F OE1 1 
ATOM   6050 N  NE2 . GLN E 5 80  ? 133.845 116.406 178.894 1.00 66.78  ? 79  GLN F NE2 1 
ATOM   6051 N  N   . PRO E 5 81  ? 133.100 121.094 179.633 1.00 68.65  ? 80  PRO F N   1 
ATOM   6052 C  CA  . PRO E 5 81  ? 133.625 122.445 179.878 1.00 68.65  ? 80  PRO F CA  1 
ATOM   6053 C  C   . PRO E 5 81  ? 134.058 123.143 178.599 1.00 68.65  ? 80  PRO F C   1 
ATOM   6054 O  O   . PRO E 5 81  ? 133.996 124.373 178.499 1.00 68.65  ? 80  PRO F O   1 
ATOM   6055 C  CB  . PRO E 5 81  ? 134.815 122.192 180.812 1.00 68.65  ? 80  PRO F CB  1 
ATOM   6056 C  CG  . PRO E 5 81  ? 134.472 120.924 181.510 1.00 68.65  ? 80  PRO F CG  1 
ATOM   6057 C  CD  . PRO E 5 81  ? 133.731 120.090 180.508 1.00 68.65  ? 80  PRO F CD  1 
ATOM   6058 N  N   . GLU E 5 82  ? 134.497 122.362 177.613 1.00 69.83  ? 81  GLU F N   1 
ATOM   6059 C  CA  . GLU E 5 82  ? 134.891 122.924 176.328 1.00 69.83  ? 81  GLU F CA  1 
ATOM   6060 C  C   . GLU E 5 82  ? 133.684 123.215 175.440 1.00 69.83  ? 81  GLU F C   1 
ATOM   6061 O  O   . GLU E 5 82  ? 133.837 123.813 174.370 1.00 69.83  ? 81  GLU F O   1 
ATOM   6062 C  CB  . GLU E 5 82  ? 135.856 121.967 175.622 1.00 69.83  ? 81  GLU F CB  1 
ATOM   6063 C  CG  . GLU E 5 82  ? 136.675 122.584 174.498 1.00 69.83  ? 81  GLU F CG  1 
ATOM   6064 C  CD  . GLU E 5 82  ? 137.834 123.417 175.012 1.00 69.83  ? 81  GLU F CD  1 
ATOM   6065 O  OE1 . GLU E 5 82  ? 138.310 123.147 176.135 1.00 69.83  ? 81  GLU F OE1 1 
ATOM   6066 O  OE2 . GLU E 5 82  ? 138.270 124.342 174.295 1.00 69.83  ? 81  GLU F OE2 1 
ATOM   6067 N  N   . ASP E 5 83  ? 132.481 122.817 175.866 1.00 66.57  ? 82  ASP F N   1 
ATOM   6068 C  CA  . ASP E 5 83  ? 131.281 122.925 175.043 1.00 66.57  ? 82  ASP F CA  1 
ATOM   6069 C  C   . ASP E 5 83  ? 130.534 124.236 175.242 1.00 66.57  ? 82  ASP F C   1 
ATOM   6070 O  O   . ASP E 5 83  ? 129.466 124.430 174.646 1.00 66.57  ? 82  ASP F O   1 
ATOM   6071 C  CB  . ASP E 5 83  ? 130.343 121.750 175.319 1.00 66.57  ? 82  ASP F CB  1 
ATOM   6072 C  CG  . ASP E 5 83  ? 130.928 120.426 174.890 1.00 66.57  ? 82  ASP F CG  1 
ATOM   6073 O  OD1 . ASP E 5 83  ? 132.095 120.411 174.446 1.00 66.57  ? 82  ASP F OD1 1 
ATOM   6074 O  OD2 . ASP E 5 83  ? 130.218 119.404 174.993 1.00 66.57  ? 82  ASP F OD2 1 
ATOM   6075 N  N   . PHE E 5 84  ? 131.056 125.143 176.062 1.00 67.31  ? 83  PHE F N   1 
ATOM   6076 C  CA  . PHE E 5 84  ? 130.418 126.435 176.288 1.00 67.31  ? 83  PHE F CA  1 
ATOM   6077 C  C   . PHE E 5 84  ? 130.912 127.402 175.218 1.00 67.31  ? 83  PHE F C   1 
ATOM   6078 O  O   . PHE E 5 84  ? 132.041 127.897 175.291 1.00 67.31  ? 83  PHE F O   1 
ATOM   6079 C  CB  . PHE E 5 84  ? 130.723 126.953 177.690 1.00 67.31  ? 83  PHE F CB  1 
ATOM   6080 C  CG  . PHE E 5 84  ? 129.972 126.238 178.774 1.00 67.31  ? 83  PHE F CG  1 
ATOM   6081 C  CD1 . PHE E 5 84  ? 128.648 125.876 178.594 1.00 67.31  ? 83  PHE F CD1 1 
ATOM   6082 C  CD2 . PHE E 5 84  ? 130.586 125.936 179.977 1.00 67.31  ? 83  PHE F CD2 1 
ATOM   6083 C  CE1 . PHE E 5 84  ? 127.952 125.220 179.591 1.00 67.31  ? 83  PHE F CE1 1 
ATOM   6084 C  CE2 . PHE E 5 84  ? 129.895 125.281 180.979 1.00 67.31  ? 83  PHE F CE2 1 
ATOM   6085 C  CZ  . PHE E 5 84  ? 128.576 124.924 180.785 1.00 67.31  ? 83  PHE F CZ  1 
ATOM   6086 N  N   . ALA E 5 85  ? 130.067 127.669 174.227 1.00 62.21  ? 84  ALA F N   1 
ATOM   6087 C  CA  . ALA E 5 85  ? 130.455 128.458 173.065 1.00 62.21  ? 84  ALA F CA  1 
ATOM   6088 C  C   . ALA E 5 85  ? 129.187 128.932 172.363 1.00 62.21  ? 84  ALA F C   1 
ATOM   6089 O  O   . ALA E 5 85  ? 128.076 128.775 172.880 1.00 62.21  ? 84  ALA F O   1 
ATOM   6090 C  CB  . ALA E 5 85  ? 131.356 127.639 172.135 1.00 62.21  ? 84  ALA F CB  1 
ATOM   6091 N  N   . THR E 5 86  ? 129.353 129.514 171.177 1.00 59.74  ? 85  THR F N   1 
ATOM   6092 C  CA  . THR E 5 86  ? 128.233 129.933 170.349 1.00 59.74  ? 85  THR F CA  1 
ATOM   6093 C  C   . THR E 5 86  ? 128.175 129.072 169.094 1.00 59.74  ? 85  THR F C   1 
ATOM   6094 O  O   . THR E 5 86  ? 129.182 128.502 168.665 1.00 59.74  ? 85  THR F O   1 
ATOM   6095 C  CB  . THR E 5 86  ? 128.325 131.417 169.968 1.00 59.74  ? 85  THR F CB  1 
ATOM   6096 O  OG1 . THR E 5 86  ? 127.115 131.817 169.313 1.00 59.74  ? 85  THR F OG1 1 
ATOM   6097 C  CG2 . THR E 5 86  ? 129.501 131.665 169.038 1.00 59.74  ? 85  THR F CG2 1 
ATOM   6098 N  N   . TYR E 5 87  ? 126.981 128.974 168.515 1.00 58.31  ? 86  TYR F N   1 
ATOM   6099 C  CA  . TYR E 5 87  ? 126.717 128.068 167.406 1.00 58.31  ? 86  TYR F CA  1 
ATOM   6100 C  C   . TYR E 5 87  ? 126.017 128.815 166.282 1.00 58.31  ? 86  TYR F C   1 
ATOM   6101 O  O   . TYR E 5 87  ? 125.143 129.649 166.535 1.00 58.31  ? 86  TYR F O   1 
ATOM   6102 C  CB  . TYR E 5 87  ? 125.863 126.884 167.869 1.00 58.31  ? 86  TYR F CB  1 
ATOM   6103 C  CG  . TYR E 5 87  ? 126.530 126.037 168.927 1.00 58.31  ? 86  TYR F CG  1 
ATOM   6104 C  CD1 . TYR E 5 87  ? 127.765 125.452 168.698 1.00 58.31  ? 86  TYR F CD1 1 
ATOM   6105 C  CD2 . TYR E 5 87  ? 125.939 125.849 170.166 1.00 58.31  ? 86  TYR F CD2 1 
ATOM   6106 C  CE1 . TYR E 5 87  ? 128.376 124.682 169.664 1.00 58.31  ? 86  TYR F CE1 1 
ATOM   6107 C  CE2 . TYR E 5 87  ? 126.545 125.082 171.138 1.00 58.31  ? 86  TYR F CE2 1 
ATOM   6108 C  CZ  . TYR E 5 87  ? 127.765 124.503 170.882 1.00 58.31  ? 86  TYR F CZ  1 
ATOM   6109 O  OH  . TYR E 5 87  ? 128.377 123.739 171.848 1.00 58.31  ? 86  TYR F OH  1 
ATOM   6110 N  N   . TYR E 5 88  ? 126.405 128.513 165.046 1.00 57.43  ? 87  TYR F N   1 
ATOM   6111 C  CA  . TYR E 5 88  ? 125.800 129.108 163.864 1.00 57.43  ? 87  TYR F CA  1 
ATOM   6112 C  C   . TYR E 5 88  ? 125.440 128.025 162.855 1.00 57.43  ? 87  TYR F C   1 
ATOM   6113 O  O   . TYR E 5 88  ? 126.128 127.007 162.742 1.00 57.43  ? 87  TYR F O   1 
ATOM   6114 C  CB  . TYR E 5 88  ? 126.737 130.128 163.201 1.00 57.43  ? 87  TYR F CB  1 
ATOM   6115 C  CG  . TYR E 5 88  ? 127.245 131.214 164.123 1.00 57.43  ? 87  TYR F CG  1 
ATOM   6116 C  CD1 . TYR E 5 88  ? 126.414 132.244 164.540 1.00 57.43  ? 87  TYR F CD1 1 
ATOM   6117 C  CD2 . TYR E 5 88  ? 128.560 131.217 164.564 1.00 57.43  ? 87  TYR F CD2 1 
ATOM   6118 C  CE1 . TYR E 5 88  ? 126.876 133.239 165.377 1.00 57.43  ? 87  TYR F CE1 1 
ATOM   6119 C  CE2 . TYR E 5 88  ? 129.030 132.207 165.402 1.00 57.43  ? 87  TYR F CE2 1 
ATOM   6120 C  CZ  . TYR E 5 88  ? 128.184 133.215 165.805 1.00 57.43  ? 87  TYR F CZ  1 
ATOM   6121 O  OH  . TYR E 5 88  ? 128.647 134.205 166.640 1.00 57.43  ? 87  TYR F OH  1 
ATOM   6122 N  N   . CYS E 5 89  ? 124.353 128.255 162.122 1.00 60.35  ? 88  CYS F N   1 
ATOM   6123 C  CA  . CYS E 5 89  ? 123.945 127.391 161.022 1.00 60.35  ? 88  CYS F CA  1 
ATOM   6124 C  C   . CYS E 5 89  ? 124.099 128.147 159.709 1.00 60.35  ? 88  CYS F C   1 
ATOM   6125 O  O   . CYS E 5 89  ? 123.570 129.253 159.557 1.00 60.35  ? 88  CYS F O   1 
ATOM   6126 C  CB  . CYS E 5 89  ? 122.504 126.899 161.201 1.00 60.35  ? 88  CYS F CB  1 
ATOM   6127 S  SG  . CYS E 5 89  ? 121.255 128.175 161.488 1.00 60.35  ? 88  CYS F SG  1 
ATOM   6128 N  N   . GLN E 5 90  ? 124.826 127.549 158.769 1.00 57.87  ? 89  GLN F N   1 
ATOM   6129 C  CA  . GLN E 5 90  ? 125.164 128.173 157.497 1.00 57.87  ? 89  GLN F CA  1 
ATOM   6130 C  C   . GLN E 5 90  ? 124.493 127.434 156.348 1.00 57.87  ? 89  GLN F C   1 
ATOM   6131 O  O   . GLN E 5 90  ? 124.515 126.199 156.301 1.00 57.87  ? 89  GLN F O   1 
ATOM   6132 C  CB  . GLN E 5 90  ? 126.678 128.191 157.278 1.00 57.87  ? 89  GLN F CB  1 
ATOM   6133 C  CG  . GLN E 5 90  ? 127.069 128.403 155.826 1.00 57.87  ? 89  GLN F CG  1 
ATOM   6134 C  CD  . GLN E 5 90  ? 128.556 128.288 155.583 1.00 57.87  ? 89  GLN F CD  1 
ATOM   6135 O  OE1 . GLN E 5 90  ? 129.346 128.185 156.518 1.00 57.87  ? 89  GLN F OE1 1 
ATOM   6136 N  NE2 . GLN E 5 90  ? 128.946 128.290 154.314 1.00 57.87  ? 89  GLN F NE2 1 
ATOM   6137 N  N   . HIS E 5 91  ? 123.906 128.196 155.426 1.00 58.59  ? 90  HIS F N   1 
ATOM   6138 C  CA  . HIS E 5 91  ? 123.374 127.648 154.188 1.00 58.59  ? 90  HIS F CA  1 
ATOM   6139 C  C   . HIS E 5 91  ? 124.472 127.562 153.136 1.00 58.59  ? 90  HIS F C   1 
ATOM   6140 O  O   . HIS E 5 91  ? 125.387 128.390 153.103 1.00 58.59  ? 90  HIS F O   1 
ATOM   6141 C  CB  . HIS E 5 91  ? 122.222 128.513 153.677 1.00 58.59  ? 90  HIS F CB  1 
ATOM   6142 C  CG  . HIS E 5 91  ? 121.468 127.908 152.536 1.00 58.59  ? 90  HIS F CG  1 
ATOM   6143 N  ND1 . HIS E 5 91  ? 121.089 128.634 151.428 1.00 58.59  ? 90  HIS F ND1 1 
ATOM   6144 C  CD2 . HIS E 5 91  ? 121.024 126.646 152.329 1.00 58.59  ? 90  HIS F CD2 1 
ATOM   6145 C  CE1 . HIS E 5 91  ? 120.443 127.846 150.588 1.00 58.59  ? 90  HIS F CE1 1 
ATOM   6146 N  NE2 . HIS E 5 91  ? 120.391 126.634 151.110 1.00 58.59  ? 90  HIS F NE2 1 
ATOM   6147 N  N   . LEU E 5 92  ? 124.374 126.557 152.267 1.00 57.54  ? 91  LEU F N   1 
ATOM   6148 C  CA  . LEU E 5 92  ? 125.414 126.280 151.282 1.00 57.54  ? 91  LEU F CA  1 
ATOM   6149 C  C   . LEU E 5 92  ? 125.045 126.724 149.872 1.00 57.54  ? 91  LEU F C   1 
ATOM   6150 O  O   . LEU E 5 92  ? 125.869 127.341 149.191 1.00 57.54  ? 91  LEU F O   1 
ATOM   6151 C  CB  . LEU E 5 92  ? 125.742 124.782 151.267 1.00 57.54  ? 91  LEU F CB  1 
ATOM   6152 C  CG  . LEU E 5 92  ? 126.772 124.254 152.272 1.00 57.54  ? 91  LEU F CG  1 
ATOM   6153 C  CD1 . LEU E 5 92  ? 126.293 124.408 153.708 1.00 57.54  ? 91  LEU F CD1 1 
ATOM   6154 C  CD2 . LEU E 5 92  ? 127.112 122.802 151.974 1.00 57.54  ? 91  LEU F CD2 1 
ATOM   6155 N  N   . ASP E 5 93  ? 123.829 126.431 149.417 1.00 59.30  ? 92  ASP F N   1 
ATOM   6156 C  CA  . ASP E 5 93  ? 123.415 126.748 148.051 1.00 59.30  ? 92  ASP F CA  1 
ATOM   6157 C  C   . ASP E 5 93  ? 122.726 128.112 148.021 1.00 59.30  ? 92  ASP F C   1 
ATOM   6158 O  O   . ASP E 5 93  ? 121.544 128.250 147.704 1.00 59.30  ? 92  ASP F O   1 
ATOM   6159 C  CB  . ASP E 5 93  ? 122.510 125.649 147.505 1.00 59.30  ? 92  ASP F CB  1 
ATOM   6160 C  CG  . ASP E 5 93  ? 122.259 125.785 146.016 1.00 59.30  ? 92  ASP F CG  1 
ATOM   6161 O  OD1 . ASP E 5 93  ? 123.017 126.520 145.348 1.00 59.30  ? 92  ASP F OD1 1 
ATOM   6162 O  OD2 . ASP E 5 93  ? 121.305 125.156 145.513 1.00 59.30  ? 92  ASP F OD2 1 
ATOM   6163 N  N   . SER E 5 94  ? 123.503 129.135 148.365 1.00 59.05  ? 93  SER F N   1 
ATOM   6164 C  CA  . SER E 5 94  ? 123.021 130.513 148.393 1.00 59.05  ? 93  SER F CA  1 
ATOM   6165 C  C   . SER E 5 94  ? 124.045 131.437 147.743 1.00 59.05  ? 93  SER F C   1 
ATOM   6166 O  O   . SER E 5 94  ? 124.423 132.473 148.291 1.00 59.05  ? 93  SER F O   1 
ATOM   6167 C  CB  . SER E 5 94  ? 122.702 130.948 149.820 1.00 59.05  ? 93  SER F CB  1 
ATOM   6168 O  OG  . SER E 5 94  ? 123.876 130.999 150.608 1.00 59.05  ? 93  SER F OG  1 
ATOM   6169 N  N   . TYR E 5 95  ? 124.513 131.053 146.563 1.00 59.92  ? 94  TYR F N   1 
ATOM   6170 C  CA  . TYR E 5 95  ? 125.490 131.855 145.840 1.00 59.92  ? 94  TYR F CA  1 
ATOM   6171 C  C   . TYR E 5 95  ? 124.898 133.216 145.487 1.00 59.92  ? 94  TYR F C   1 
ATOM   6172 O  O   . TYR E 5 95  ? 123.825 133.278 144.870 1.00 59.92  ? 94  TYR F O   1 
ATOM   6173 C  CB  . TYR E 5 95  ? 125.918 131.123 144.569 1.00 59.92  ? 94  TYR F CB  1 
ATOM   6174 C  CG  . TYR E 5 95  ? 127.087 131.742 143.840 1.00 59.92  ? 94  TYR F CG  1 
ATOM   6175 C  CD1 . TYR E 5 95  ? 128.387 131.532 144.271 1.00 59.92  ? 94  TYR F CD1 1 
ATOM   6176 C  CD2 . TYR E 5 95  ? 126.889 132.531 142.716 1.00 59.92  ? 94  TYR F CD2 1 
ATOM   6177 C  CE1 . TYR E 5 95  ? 129.458 132.089 143.602 1.00 59.92  ? 94  TYR F CE1 1 
ATOM   6178 C  CE2 . TYR E 5 95  ? 127.954 133.096 142.043 1.00 59.92  ? 94  TYR F CE2 1 
ATOM   6179 C  CZ  . TYR E 5 95  ? 129.237 132.872 142.492 1.00 59.92  ? 94  TYR F CZ  1 
ATOM   6180 O  OH  . TYR E 5 95  ? 130.303 133.432 141.828 1.00 59.92  ? 94  TYR F OH  1 
ATOM   6181 N  N   . PRO E 5 96  ? 125.557 134.328 145.852 1.00 59.75  ? 95  PRO F N   1 
ATOM   6182 C  CA  . PRO E 5 96  ? 126.777 134.379 146.659 1.00 59.75  ? 95  PRO F CA  1 
ATOM   6183 C  C   . PRO E 5 96  ? 126.534 134.852 148.092 1.00 59.75  ? 95  PRO F C   1 
ATOM   6184 O  O   . PRO E 5 96  ? 127.474 135.279 148.760 1.00 59.75  ? 95  PRO F O   1 
ATOM   6185 C  CB  . PRO E 5 96  ? 127.641 135.390 145.902 1.00 59.75  ? 95  PRO F CB  1 
ATOM   6186 C  CG  . PRO E 5 96  ? 126.650 136.240 145.099 1.00 59.75  ? 95  PRO F CG  1 
ATOM   6187 C  CD  . PRO E 5 96  ? 125.273 135.638 145.249 1.00 59.75  ? 95  PRO F CD  1 
ATOM   6188 N  N   . LEU E 5 97  A 125.286 134.786 148.552 1.00 62.39  ? 95  LEU F N   1 
ATOM   6189 C  CA  . LEU E 5 97  A 124.932 135.229 149.902 1.00 62.39  ? 95  LEU F CA  1 
ATOM   6190 C  C   . LEU E 5 97  A 124.916 134.029 150.850 1.00 62.39  ? 95  LEU F C   1 
ATOM   6191 O  O   . LEU E 5 97  A 123.870 133.497 151.224 1.00 62.39  ? 95  LEU F O   1 
ATOM   6192 C  CB  . LEU E 5 97  A 123.588 135.946 149.891 1.00 62.39  ? 95  LEU F CB  1 
ATOM   6193 C  CG  . LEU E 5 97  A 123.463 137.204 149.035 1.00 62.39  ? 95  LEU F CG  1 
ATOM   6194 C  CD1 . LEU E 5 97  A 122.044 137.351 148.513 1.00 62.39  ? 95  LEU F CD1 1 
ATOM   6195 C  CD2 . LEU E 5 97  A 123.864 138.426 149.840 1.00 62.39  ? 95  LEU F CD2 1 
ATOM   6196 N  N   . PHE E 5 98  ? 126.117 133.611 151.253 1.00 58.80  ? 96  PHE F N   1 
ATOM   6197 C  CA  . PHE E 5 98  ? 126.237 132.461 152.141 1.00 58.80  ? 96  PHE F CA  1 
ATOM   6198 C  C   . PHE E 5 98  ? 125.747 132.835 153.533 1.00 58.80  ? 96  PHE F C   1 
ATOM   6199 O  O   . PHE E 5 98  ? 126.507 133.356 154.354 1.00 58.80  ? 96  PHE F O   1 
ATOM   6200 C  CB  . PHE E 5 98  ? 127.678 131.952 152.182 1.00 58.80  ? 96  PHE F CB  1 
ATOM   6201 C  CG  . PHE E 5 98  ? 128.143 131.352 150.885 1.00 58.80  ? 96  PHE F CG  1 
ATOM   6202 C  CD1 . PHE E 5 98  ? 127.279 130.601 150.106 1.00 58.80  ? 96  PHE F CD1 1 
ATOM   6203 C  CD2 . PHE E 5 98  ? 129.442 131.534 150.447 1.00 58.80  ? 96  PHE F CD2 1 
ATOM   6204 C  CE1 . PHE E 5 98  ? 127.702 130.050 148.912 1.00 58.80  ? 96  PHE F CE1 1 
ATOM   6205 C  CE2 . PHE E 5 98  ? 129.869 130.985 149.254 1.00 58.80  ? 96  PHE F CE2 1 
ATOM   6206 C  CZ  . PHE E 5 98  ? 128.999 130.242 148.487 1.00 58.80  ? 96  PHE F CZ  1 
ATOM   6207 N  N   . THR E 5 99  ? 124.471 132.568 153.795 1.00 58.12  ? 97  THR F N   1 
ATOM   6208 C  CA  . THR E 5 99  ? 123.832 133.035 155.016 1.00 58.12  ? 97  THR F CA  1 
ATOM   6209 C  C   . THR E 5 99  ? 124.333 132.263 156.230 1.00 58.12  ? 97  THR F C   1 
ATOM   6210 O  O   . THR E 5 99  ? 124.495 131.040 156.188 1.00 58.12  ? 97  THR F O   1 
ATOM   6211 C  CB  . THR E 5 99  ? 122.314 132.897 154.900 1.00 58.12  ? 97  THR F CB  1 
ATOM   6212 O  OG1 . THR E 5 99  ? 121.872 133.493 153.674 1.00 58.12  ? 97  THR F OG1 1 
ATOM   6213 C  CG2 . THR E 5 99  ? 121.619 133.584 156.068 1.00 58.12  ? 97  THR F CG2 1 
ATOM   6214 N  N   . PHE E 5 100 ? 124.581 132.989 157.314 1.00 55.52  ? 98  PHE F N   1 
ATOM   6215 C  CA  . PHE E 5 100 ? 124.903 132.408 158.607 1.00 55.52  ? 98  PHE F CA  1 
ATOM   6216 C  C   . PHE E 5 100 ? 123.745 132.627 159.571 1.00 55.52  ? 98  PHE F C   1 
ATOM   6217 O  O   . PHE E 5 100 ? 122.903 133.508 159.377 1.00 55.52  ? 98  PHE F O   1 
ATOM   6218 C  CB  . PHE E 5 100 ? 126.182 133.019 159.186 1.00 55.52  ? 98  PHE F CB  1 
ATOM   6219 C  CG  . PHE E 5 100 ? 127.445 132.430 158.632 1.00 55.52  ? 98  PHE F CG  1 
ATOM   6220 C  CD1 . PHE E 5 100 ? 127.771 132.584 157.298 1.00 55.52  ? 98  PHE F CD1 1 
ATOM   6221 C  CD2 . PHE E 5 100 ? 128.316 131.736 159.452 1.00 55.52  ? 98  PHE F CD2 1 
ATOM   6222 C  CE1 . PHE E 5 100 ? 128.937 132.049 156.791 1.00 55.52  ? 98  PHE F CE1 1 
ATOM   6223 C  CE2 . PHE E 5 100 ? 129.482 131.200 158.950 1.00 55.52  ? 98  PHE F CE2 1 
ATOM   6224 C  CZ  . PHE E 5 100 ? 129.793 131.356 157.619 1.00 55.52  ? 98  PHE F CZ  1 
ATOM   6225 N  N   . GLY E 5 101 ? 123.709 131.810 160.618 1.00 59.79  ? 99  GLY F N   1 
ATOM   6226 C  CA  . GLY E 5 101 ? 122.690 131.928 161.632 1.00 59.79  ? 99  GLY F CA  1 
ATOM   6227 C  C   . GLY E 5 101 ? 122.924 133.122 162.533 1.00 59.79  ? 99  GLY F C   1 
ATOM   6228 O  O   . GLY E 5 101 ? 124.054 133.591 162.699 1.00 59.79  ? 99  GLY F O   1 
ATOM   6229 N  N   . PRO E 5 102 ? 121.848 133.648 163.126 1.00 62.27  ? 100 PRO F N   1 
ATOM   6230 C  CA  . PRO E 5 102 ? 122.014 134.776 164.059 1.00 62.27  ? 100 PRO F CA  1 
ATOM   6231 C  C   . PRO E 5 102 ? 122.913 134.457 165.241 1.00 62.27  ? 100 PRO F C   1 
ATOM   6232 O  O   . PRO E 5 102 ? 123.674 135.325 165.686 1.00 62.27  ? 100 PRO F O   1 
ATOM   6233 C  CB  . PRO E 5 102 ? 120.574 135.076 164.501 1.00 62.27  ? 100 PRO F CB  1 
ATOM   6234 C  CG  . PRO E 5 102 ? 119.714 134.514 163.417 1.00 62.27  ? 100 PRO F CG  1 
ATOM   6235 C  CD  . PRO E 5 102 ? 120.434 133.302 162.914 1.00 62.27  ? 100 PRO F CD  1 
ATOM   6236 N  N   . GLY E 5 103 ? 122.852 133.234 165.763 1.00 62.56  ? 101 GLY F N   1 
ATOM   6237 C  CA  . GLY E 5 103 ? 123.720 132.846 166.857 1.00 62.56  ? 101 GLY F CA  1 
ATOM   6238 C  C   . GLY E 5 103 ? 123.001 132.396 168.113 1.00 62.56  ? 101 GLY F C   1 
ATOM   6239 O  O   . GLY E 5 103 ? 122.093 133.077 168.600 1.00 62.56  ? 101 GLY F O   1 
ATOM   6240 N  N   . THR E 5 104 ? 123.403 131.244 168.643 1.00 62.14  ? 102 THR F N   1 
ATOM   6241 C  CA  . THR E 5 104 ? 122.885 130.715 169.897 1.00 62.14  ? 102 THR F CA  1 
ATOM   6242 C  C   . THR E 5 104 ? 124.025 130.616 170.901 1.00 62.14  ? 102 THR F C   1 
ATOM   6243 O  O   . THR E 5 104 ? 125.087 130.070 170.586 1.00 62.14  ? 102 THR F O   1 
ATOM   6244 C  CB  . THR E 5 104 ? 122.241 129.341 169.692 1.00 62.14  ? 102 THR F CB  1 
ATOM   6245 O  OG1 . THR E 5 104 ? 120.972 129.496 169.044 1.00 62.14  ? 102 THR F OG1 1 
ATOM   6246 C  CG2 . THR E 5 104 ? 122.051 128.625 171.021 1.00 62.14  ? 102 THR F CG2 1 
ATOM   6247 N  N   . LYS E 5 105 ? 123.804 131.140 172.102 1.00 65.75  ? 103 LYS F N   1 
ATOM   6248 C  CA  . LYS E 5 105 ? 124.798 131.114 173.164 1.00 65.75  ? 103 LYS F CA  1 
ATOM   6249 C  C   . LYS E 5 105 ? 124.285 130.272 174.322 1.00 65.75  ? 103 LYS F C   1 
ATOM   6250 O  O   . LYS E 5 105 ? 123.133 130.414 174.744 1.00 65.75  ? 103 LYS F O   1 
ATOM   6251 C  CB  . LYS E 5 105 ? 125.131 132.529 173.648 1.00 65.75  ? 103 LYS F CB  1 
ATOM   6252 C  CG  . LYS E 5 105 ? 126.103 132.572 174.816 1.00 65.75  ? 103 LYS F CG  1 
ATOM   6253 C  CD  . LYS E 5 105 ? 127.073 133.735 174.687 1.00 65.75  ? 103 LYS F CD  1 
ATOM   6254 C  CE  . LYS E 5 105 ? 128.061 133.759 175.841 1.00 65.75  ? 103 LYS F CE  1 
ATOM   6255 N  NZ  . LYS E 5 105 ? 129.315 133.024 175.517 1.00 65.75  ? 103 LYS F NZ  1 
ATOM   6256 N  N   . VAL E 5 106 ? 125.146 129.393 174.831 1.00 68.27  ? 104 VAL F N   1 
ATOM   6257 C  CA  . VAL E 5 106 ? 124.817 128.509 175.941 1.00 68.27  ? 104 VAL F CA  1 
ATOM   6258 C  C   . VAL E 5 106 ? 125.802 128.765 177.073 1.00 68.27  ? 104 VAL F C   1 
ATOM   6259 O  O   . VAL E 5 106 ? 127.011 128.878 176.845 1.00 68.27  ? 104 VAL F O   1 
ATOM   6260 C  CB  . VAL E 5 106 ? 124.834 127.025 175.519 1.00 68.27  ? 104 VAL F CB  1 
ATOM   6261 C  CG1 . VAL E 5 106 ? 123.620 126.710 174.661 1.00 68.27  ? 104 VAL F CG1 1 
ATOM   6262 C  CG2 . VAL E 5 106 ? 126.114 126.696 174.768 1.00 68.27  ? 104 VAL F CG2 1 
ATOM   6263 N  N   . ASP E 5 107 ? 125.279 128.869 178.293 1.00 72.02  ? 105 ASP F N   1 
ATOM   6264 C  CA  . ASP E 5 107 ? 126.083 129.187 179.462 1.00 72.02  ? 105 ASP F CA  1 
ATOM   6265 C  C   . ASP E 5 107 ? 125.734 128.243 180.604 1.00 72.02  ? 105 ASP F C   1 
ATOM   6266 O  O   . ASP E 5 107 ? 124.818 127.423 180.506 1.00 72.02  ? 105 ASP F O   1 
ATOM   6267 C  CB  . ASP E 5 107 ? 125.880 130.643 179.904 1.00 72.02  ? 105 ASP F CB  1 
ATOM   6268 C  CG  . ASP E 5 107 ? 124.419 131.047 179.928 1.00 72.02  ? 105 ASP F CG  1 
ATOM   6269 O  OD1 . ASP E 5 107 ? 123.582 130.288 179.396 1.00 72.02  ? 105 ASP F OD1 1 
ATOM   6270 O  OD2 . ASP E 5 107 ? 124.107 132.124 180.479 1.00 72.02  ? 105 ASP F OD2 1 
ATOM   6271 N  N   . ILE E 5 108 ? 126.487 128.373 181.698 1.00 69.83  ? 106 ILE F N   1 
ATOM   6272 C  CA  . ILE E 5 108 ? 126.283 127.506 182.851 1.00 69.83  ? 106 ILE F CA  1 
ATOM   6273 C  C   . ILE E 5 108 ? 125.008 127.908 183.579 1.00 69.83  ? 106 ILE F C   1 
ATOM   6274 O  O   . ILE E 5 108 ? 124.736 129.097 183.795 1.00 69.83  ? 106 ILE F O   1 
ATOM   6275 C  CB  . ILE E 5 108 ? 127.507 127.561 183.781 1.00 69.83  ? 106 ILE F CB  1 
ATOM   6276 C  CG1 . ILE E 5 108 ? 127.226 126.823 185.092 1.00 69.83  ? 106 ILE F CG1 1 
ATOM   6277 C  CG2 . ILE E 5 108 ? 127.922 129.003 184.043 1.00 69.83  ? 106 ILE F CG2 1 
ATOM   6278 C  CD1 . ILE E 5 108 ? 128.465 126.544 185.914 1.00 69.83  ? 106 ILE F CD1 1 
ATOM   6279 N  N   . LYS E 5 109 ? 124.211 126.910 183.950 1.00 71.13  ? 107 LYS F N   1 
ATOM   6280 C  CA  . LYS E 5 109 ? 122.937 127.169 184.606 1.00 71.13  ? 107 LYS F CA  1 
ATOM   6281 C  C   . LYS E 5 109 ? 123.154 127.759 185.994 1.00 71.13  ? 107 LYS F C   1 
ATOM   6282 O  O   . LYS E 5 109 ? 124.115 127.421 186.690 1.00 71.13  ? 107 LYS F O   1 
ATOM   6283 C  CB  . LYS E 5 109 ? 122.120 125.881 184.705 1.00 71.13  ? 107 LYS F CB  1 
ATOM   6284 C  CG  . LYS E 5 109 ? 120.647 126.100 185.009 1.00 71.13  ? 107 LYS F CG  1 
ATOM   6285 C  CD  . LYS E 5 109 ? 119.913 124.779 185.171 1.00 71.13  ? 107 LYS F CD  1 
ATOM   6286 C  CE  . LYS E 5 109 ? 119.757 124.067 183.837 1.00 71.13  ? 107 LYS F CE  1 
ATOM   6287 N  NZ  . LYS E 5 109 ? 118.373 123.553 183.640 1.00 71.13  ? 107 LYS F NZ  1 
ATOM   6288 N  N   . ARG E 5 110 ? 122.249 128.649 186.392 1.00 73.05  ? 108 ARG F N   1 
ATOM   6289 C  CA  . ARG E 5 110 ? 122.323 129.302 187.693 1.00 73.05  ? 108 ARG F CA  1 
ATOM   6290 C  C   . ARG E 5 110 ? 121.242 128.778 188.632 1.00 73.05  ? 108 ARG F C   1 
ATOM   6291 O  O   . ARG E 5 110 ? 120.051 128.886 188.343 1.00 73.05  ? 108 ARG F O   1 
ATOM   6292 C  CB  . ARG E 5 110 ? 122.196 130.819 187.536 1.00 73.05  ? 108 ARG F CB  1 
ATOM   6293 C  CG  . ARG E 5 110 ? 121.940 131.564 188.836 1.00 73.05  ? 108 ARG F CG  1 
ATOM   6294 C  CD  . ARG E 5 110 ? 121.916 133.068 188.613 1.00 73.05  ? 108 ARG F CD  1 
ATOM   6295 N  NE  . ARG E 5 110 ? 121.493 133.793 189.805 1.00 73.05  ? 108 ARG F NE  1 
ATOM   6296 C  CZ  . ARG E 5 110 ? 120.260 134.233 190.017 1.00 73.05  ? 108 ARG F CZ  1 
ATOM   6297 N  NH1 . ARG E 5 110 ? 119.297 134.045 189.129 1.00 73.05  ? 108 ARG F NH1 1 
ATOM   6298 N  NH2 . ARG E 5 110 ? 119.987 134.879 191.146 1.00 73.05  ? 108 ARG F NH2 1 
HETATM 6299 C  C1  . NAG F 6 .   ? 122.241 105.511 155.899 1.00 81.81  ? 1   NAG D C1  1 
HETATM 6300 C  C2  . NAG F 6 .   ? 122.470 105.827 157.372 1.00 81.81  ? 1   NAG D C2  1 
HETATM 6301 C  C3  . NAG F 6 .   ? 122.670 104.536 158.161 1.00 81.81  ? 1   NAG D C3  1 
HETATM 6302 C  C4  . NAG F 6 .   ? 121.525 103.563 157.904 1.00 81.81  ? 1   NAG D C4  1 
HETATM 6303 C  C5  . NAG F 6 .   ? 121.305 103.373 156.404 1.00 81.81  ? 1   NAG D C5  1 
HETATM 6304 C  C6  . NAG F 6 .   ? 120.083 102.544 156.083 1.00 81.81  ? 1   NAG D C6  1 
HETATM 6305 C  C7  . NAG F 6 .   ? 123.489 108.011 157.838 1.00 81.81  ? 1   NAG D C7  1 
HETATM 6306 C  C8  . NAG F 6 .   ? 124.771 108.775 157.979 1.00 81.81  ? 1   NAG D C8  1 
HETATM 6307 N  N2  . NAG F 6 .   ? 123.610 106.712 157.544 1.00 81.81  ? 1   NAG D N2  1 
HETATM 6308 O  O3  . NAG F 6 .   ? 122.750 104.837 159.549 1.00 81.81  ? 1   NAG D O3  1 
HETATM 6309 O  O4  . NAG F 6 .   ? 121.840 102.303 158.484 1.00 81.81  ? 1   NAG D O4  1 
HETATM 6310 O  O5  . NAG F 6 .   ? 121.120 104.645 155.765 1.00 81.81  ? 1   NAG D O5  1 
HETATM 6311 O  O6  . NAG F 6 .   ? 119.834 102.503 154.685 1.00 81.81  ? 1   NAG D O6  1 
HETATM 6312 O  O7  . NAG F 6 .   ? 122.394 108.545 157.984 1.00 81.81  ? 1   NAG D O7  1 
HETATM 6313 C  C1  . NAG F 6 .   ? 120.904 101.986 159.533 1.00 91.32  ? 2   NAG D C1  1 
HETATM 6314 C  C2  . NAG F 6 .   ? 121.100 100.518 159.908 1.00 91.32  ? 2   NAG D C2  1 
HETATM 6315 C  C3  . NAG F 6 .   ? 120.159 100.133 161.045 1.00 91.32  ? 2   NAG D C3  1 
HETATM 6316 C  C4  . NAG F 6 .   ? 120.329 101.087 162.220 1.00 91.32  ? 2   NAG D C4  1 
HETATM 6317 C  C5  . NAG F 6 .   ? 120.173 102.533 161.756 1.00 91.32  ? 2   NAG D C5  1 
HETATM 6318 C  C6  . NAG F 6 .   ? 120.454 103.539 162.848 1.00 91.32  ? 2   NAG D C6  1 
HETATM 6319 C  C7  . NAG F 6 .   ? 121.897 99.100  158.069 1.00 91.32  ? 2   NAG D C7  1 
HETATM 6320 C  C8  . NAG F 6 .   ? 121.502 98.235  156.910 1.00 91.32  ? 2   NAG D C8  1 
HETATM 6321 N  N2  . NAG F 6 .   ? 120.892 99.653  158.757 1.00 91.32  ? 2   NAG D N2  1 
HETATM 6322 O  O3  . NAG F 6 .   ? 120.433 98.799  161.457 1.00 91.32  ? 2   NAG D O3  1 
HETATM 6323 O  O4  . NAG F 6 .   ? 119.355 100.808 163.219 1.00 91.32  ? 2   NAG D O4  1 
HETATM 6324 O  O5  . NAG F 6 .   ? 121.097 102.809 160.692 1.00 91.32  ? 2   NAG D O5  1 
HETATM 6325 O  O6  . NAG F 6 .   ? 120.774 104.814 162.311 1.00 91.32  ? 2   NAG D O6  1 
HETATM 6326 O  O7  . NAG F 6 .   ? 123.072 99.290  158.369 1.00 91.32  ? 2   NAG D O7  1 
HETATM 6327 CA CA  . CA  G 7 .   ? 137.175 119.709 132.015 1.00 50.19  ? 501 CA  A CA  1 
# 
