data_8YX5
# 
_entry.id   8YX5 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.399 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8YX5         pdb_00008yx5 10.2210/pdb8yx5/pdb 
WWPDB D_1300046509 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2024-12-04 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8YX5 
_pdbx_database_status.recvd_initial_deposition_date   2024-04-02 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           N 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              shang_jinsai@gzlab.ac.cn 
_pdbx_contact_author.name_first         Jinsai 
_pdbx_contact_author.name_last          Shang 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0001-8164-1544 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Lu, Y.'    1 0000-0002-9985-8546 
'Shang, J.' 2 0000-0001-8164-1544 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Nat Commun' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2041-1723 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            15 
_citation.language                  ? 
_citation.page_first                10169 
_citation.page_last                 10169 
_citation.title                     
'Discovery of orally bioavailable SARS-CoV-2 papain-like protease inhibitor as a potential treatment for COVID-19.' 
_citation.year                      2024 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1038/s41467-024-54462-0 
_citation.pdbx_database_id_PubMed   39580525 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Lu, Y.'      1  0000-0002-9985-8546 
primary 'Yang, Q.'    2  0009-0009-1648-4189 
primary 'Ran, T.'     3  0000-0002-1387-4634 
primary 'Zhang, G.'   4  ?                   
primary 'Li, W.'      5  ?                   
primary 'Zhou, P.'    6  ?                   
primary 'Tang, J.'    7  ?                   
primary 'Dai, M.'     8  ?                   
primary 'Zhong, J.'   9  ?                   
primary 'Chen, H.'    10 ?                   
primary 'He, P.'      11 ?                   
primary 'Zhou, A.'    12 ?                   
primary 'Xue, B.'     13 ?                   
primary 'Chen, J.'    14 ?                   
primary 'Zhang, J.'   15 ?                   
primary 'Yang, S.'    16 ?                   
primary 'Wu, K.'      17 ?                   
primary 'Wu, X.'      18 ?                   
primary 'Tang, M.'    19 ?                   
primary 'Zhang, W.K.' 20 0000-0003-4960-6137 
primary 'Guo, D.'     21 0000-0002-8297-0814 
primary 'Chen, X.'    22 0000-0002-4052-8155 
primary 'Chen, H.'    23 0000-0002-8065-8333 
primary 'Shang, J.'   24 0000-0001-8164-1544 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Papain-like protease nsp3' 35712.484 2   3.4.19.12,3.4.22.- ? ? ? 
2 non-polymer syn 
;5-[(1~{R},5~{S})-3,6-diazabicyclo[3.1.1]heptan-3-yl]-2-methyl-~{N}-[1-(1-methyl-2-oxidanylidene-benzo[cd]indol-6-yl)cyclopropyl]benzamide
;
452.548   2   ?                  ? ? ? 
3 non-polymer syn 'ZINC ION' 65.409    4   ?                  ? ? ? 
4 non-polymer syn GLYCEROL 92.094    4   ?                  ? ? ? 
5 water       nat water 18.015    539 ?                  ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        'Non-structural protein 3,nsp3,PL2-PRO,Papain-like proteinase,PL-PRO' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;GEVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTLRVEAFEYYHTTDPSF
LGRYMSALNHTKKWKYPQVNGLTSIKWADNNSYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTV
GELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQES
PFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVFYKENSYTTTIK
;
_entity_poly.pdbx_seq_one_letter_code_can   
;GEVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTLRVEAFEYYHTTDPSF
LGRYMSALNHTKKWKYPQVNGLTSIKWADNNSYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTV
GELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQES
PFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVFYKENSYTTTIK
;
_entity_poly.pdbx_strand_id                 A,B 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 
;5-[(1~{R},5~{S})-3,6-diazabicyclo[3.1.1]heptan-3-yl]-2-methyl-~{N}-[1-(1-methyl-2-oxidanylidene-benzo[cd]indol-6-yl)cyclopropyl]benzamide
;
A1LZ8 
3 'ZINC ION' ZN    
4 GLYCEROL GOL   
5 water HOH   
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   GLY n 
1 2   GLU n 
1 3   VAL n 
1 4   ARG n 
1 5   THR n 
1 6   ILE n 
1 7   LYS n 
1 8   VAL n 
1 9   PHE n 
1 10  THR n 
1 11  THR n 
1 12  VAL n 
1 13  ASP n 
1 14  ASN n 
1 15  ILE n 
1 16  ASN n 
1 17  LEU n 
1 18  HIS n 
1 19  THR n 
1 20  GLN n 
1 21  VAL n 
1 22  VAL n 
1 23  ASP n 
1 24  MET n 
1 25  SER n 
1 26  MET n 
1 27  THR n 
1 28  TYR n 
1 29  GLY n 
1 30  GLN n 
1 31  GLN n 
1 32  PHE n 
1 33  GLY n 
1 34  PRO n 
1 35  THR n 
1 36  TYR n 
1 37  LEU n 
1 38  ASP n 
1 39  GLY n 
1 40  ALA n 
1 41  ASP n 
1 42  VAL n 
1 43  THR n 
1 44  LYS n 
1 45  ILE n 
1 46  LYS n 
1 47  PRO n 
1 48  HIS n 
1 49  ASN n 
1 50  SER n 
1 51  HIS n 
1 52  GLU n 
1 53  GLY n 
1 54  LYS n 
1 55  THR n 
1 56  PHE n 
1 57  TYR n 
1 58  VAL n 
1 59  LEU n 
1 60  PRO n 
1 61  ASN n 
1 62  ASP n 
1 63  ASP n 
1 64  THR n 
1 65  LEU n 
1 66  ARG n 
1 67  VAL n 
1 68  GLU n 
1 69  ALA n 
1 70  PHE n 
1 71  GLU n 
1 72  TYR n 
1 73  TYR n 
1 74  HIS n 
1 75  THR n 
1 76  THR n 
1 77  ASP n 
1 78  PRO n 
1 79  SER n 
1 80  PHE n 
1 81  LEU n 
1 82  GLY n 
1 83  ARG n 
1 84  TYR n 
1 85  MET n 
1 86  SER n 
1 87  ALA n 
1 88  LEU n 
1 89  ASN n 
1 90  HIS n 
1 91  THR n 
1 92  LYS n 
1 93  LYS n 
1 94  TRP n 
1 95  LYS n 
1 96  TYR n 
1 97  PRO n 
1 98  GLN n 
1 99  VAL n 
1 100 ASN n 
1 101 GLY n 
1 102 LEU n 
1 103 THR n 
1 104 SER n 
1 105 ILE n 
1 106 LYS n 
1 107 TRP n 
1 108 ALA n 
1 109 ASP n 
1 110 ASN n 
1 111 ASN n 
1 112 SER n 
1 113 TYR n 
1 114 LEU n 
1 115 ALA n 
1 116 THR n 
1 117 ALA n 
1 118 LEU n 
1 119 LEU n 
1 120 THR n 
1 121 LEU n 
1 122 GLN n 
1 123 GLN n 
1 124 ILE n 
1 125 GLU n 
1 126 LEU n 
1 127 LYS n 
1 128 PHE n 
1 129 ASN n 
1 130 PRO n 
1 131 PRO n 
1 132 ALA n 
1 133 LEU n 
1 134 GLN n 
1 135 ASP n 
1 136 ALA n 
1 137 TYR n 
1 138 TYR n 
1 139 ARG n 
1 140 ALA n 
1 141 ARG n 
1 142 ALA n 
1 143 GLY n 
1 144 GLU n 
1 145 ALA n 
1 146 ALA n 
1 147 ASN n 
1 148 PHE n 
1 149 CYS n 
1 150 ALA n 
1 151 LEU n 
1 152 ILE n 
1 153 LEU n 
1 154 ALA n 
1 155 TYR n 
1 156 CYS n 
1 157 ASN n 
1 158 LYS n 
1 159 THR n 
1 160 VAL n 
1 161 GLY n 
1 162 GLU n 
1 163 LEU n 
1 164 GLY n 
1 165 ASP n 
1 166 VAL n 
1 167 ARG n 
1 168 GLU n 
1 169 THR n 
1 170 MET n 
1 171 SER n 
1 172 TYR n 
1 173 LEU n 
1 174 PHE n 
1 175 GLN n 
1 176 HIS n 
1 177 ALA n 
1 178 ASN n 
1 179 LEU n 
1 180 ASP n 
1 181 SER n 
1 182 CYS n 
1 183 LYS n 
1 184 ARG n 
1 185 VAL n 
1 186 LEU n 
1 187 ASN n 
1 188 VAL n 
1 189 VAL n 
1 190 CYS n 
1 191 LYS n 
1 192 THR n 
1 193 CYS n 
1 194 GLY n 
1 195 GLN n 
1 196 GLN n 
1 197 GLN n 
1 198 THR n 
1 199 THR n 
1 200 LEU n 
1 201 LYS n 
1 202 GLY n 
1 203 VAL n 
1 204 GLU n 
1 205 ALA n 
1 206 VAL n 
1 207 MET n 
1 208 TYR n 
1 209 MET n 
1 210 GLY n 
1 211 THR n 
1 212 LEU n 
1 213 SER n 
1 214 TYR n 
1 215 GLU n 
1 216 GLN n 
1 217 PHE n 
1 218 LYS n 
1 219 LYS n 
1 220 GLY n 
1 221 VAL n 
1 222 GLN n 
1 223 ILE n 
1 224 PRO n 
1 225 CYS n 
1 226 THR n 
1 227 CYS n 
1 228 GLY n 
1 229 LYS n 
1 230 GLN n 
1 231 ALA n 
1 232 THR n 
1 233 LYS n 
1 234 TYR n 
1 235 LEU n 
1 236 VAL n 
1 237 GLN n 
1 238 GLN n 
1 239 GLU n 
1 240 SER n 
1 241 PRO n 
1 242 PHE n 
1 243 VAL n 
1 244 MET n 
1 245 MET n 
1 246 SER n 
1 247 ALA n 
1 248 PRO n 
1 249 PRO n 
1 250 ALA n 
1 251 GLN n 
1 252 TYR n 
1 253 GLU n 
1 254 LEU n 
1 255 LYS n 
1 256 HIS n 
1 257 GLY n 
1 258 THR n 
1 259 PHE n 
1 260 THR n 
1 261 CYS n 
1 262 ALA n 
1 263 SER n 
1 264 GLU n 
1 265 TYR n 
1 266 THR n 
1 267 GLY n 
1 268 ASN n 
1 269 TYR n 
1 270 GLN n 
1 271 CYS n 
1 272 GLY n 
1 273 HIS n 
1 274 TYR n 
1 275 LYS n 
1 276 HIS n 
1 277 ILE n 
1 278 THR n 
1 279 SER n 
1 280 LYS n 
1 281 GLU n 
1 282 THR n 
1 283 LEU n 
1 284 TYR n 
1 285 CYS n 
1 286 ILE n 
1 287 ASP n 
1 288 GLY n 
1 289 ALA n 
1 290 LEU n 
1 291 LEU n 
1 292 THR n 
1 293 LYS n 
1 294 SER n 
1 295 SER n 
1 296 GLU n 
1 297 TYR n 
1 298 LYS n 
1 299 GLY n 
1 300 PRO n 
1 301 ILE n 
1 302 THR n 
1 303 ASP n 
1 304 VAL n 
1 305 PHE n 
1 306 TYR n 
1 307 LYS n 
1 308 GLU n 
1 309 ASN n 
1 310 SER n 
1 311 TYR n 
1 312 THR n 
1 313 THR n 
1 314 THR n 
1 315 ILE n 
1 316 LYS n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   316 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 'rep, 1a-1b' 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Severe acute respiratory syndrome coronavirus 2' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     2697049 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli BL21(DE3)' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     469008 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
A1LZ8 non-polymer         . 
;5-[(1~{R},5~{S})-3,6-diazabicyclo[3.1.1]heptan-3-yl]-2-methyl-~{N}-[1-(1-methyl-2-oxidanylidene-benzo[cd]indol-6-yl)cyclopropyl]benzamide
;
?                               'C28 H28 N4 O2'  452.548 
ALA   'L-peptide linking' y ALANINE ?                               'C3 H7 N O2'     89.093  
ARG   'L-peptide linking' y ARGININE ?                               'C6 H15 N4 O2 1' 175.209 
ASN   'L-peptide linking' y ASPARAGINE ?                               'C4 H8 N2 O3'    132.118 
ASP   'L-peptide linking' y 'ASPARTIC ACID' ?                               'C4 H7 N O4'     133.103 
CYS   'L-peptide linking' y CYSTEINE ?                               'C3 H7 N O2 S'   121.158 
GLN   'L-peptide linking' y GLUTAMINE ?                               'C5 H10 N2 O3'   146.144 
GLU   'L-peptide linking' y 'GLUTAMIC ACID' ?                               'C5 H9 N O4'     147.129 
GLY   'peptide linking'   y GLYCINE ?                               'C2 H5 N O2'     75.067  
GOL   non-polymer         . GLYCEROL 'GLYCERIN; PROPANE-1,2,3-TRIOL' 'C3 H8 O3'       92.094  
HIS   'L-peptide linking' y HISTIDINE ?                               'C6 H10 N3 O2 1' 156.162 
HOH   non-polymer         . WATER ?                               'H2 O'           18.015  
ILE   'L-peptide linking' y ISOLEUCINE ?                               'C6 H13 N O2'    131.173 
LEU   'L-peptide linking' y LEUCINE ?                               'C6 H13 N O2'    131.173 
LYS   'L-peptide linking' y LYSINE ?                               'C6 H15 N2 O2 1' 147.195 
MET   'L-peptide linking' y METHIONINE ?                               'C5 H11 N O2 S'  149.211 
PHE   'L-peptide linking' y PHENYLALANINE ?                               'C9 H11 N O2'    165.189 
PRO   'L-peptide linking' y PROLINE ?                               'C5 H9 N O2'     115.130 
SER   'L-peptide linking' y SERINE ?                               'C3 H7 N O3'     105.093 
THR   'L-peptide linking' y THREONINE ?                               'C4 H9 N O3'     119.119 
TRP   'L-peptide linking' y TRYPTOPHAN ?                               'C11 H12 N2 O2'  204.225 
TYR   'L-peptide linking' y TYROSINE ?                               'C9 H11 N O3'    181.189 
VAL   'L-peptide linking' y VALINE ?                               'C5 H11 N O2'    117.146 
ZN    non-polymer         . 'ZINC ION' ?                               'Zn 2'           65.409  
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   GLY 1   0   0   GLY GLY A . n 
A 1 2   GLU 2   1   1   GLU GLU A . n 
A 1 3   VAL 3   2   2   VAL VAL A . n 
A 1 4   ARG 4   3   3   ARG ARG A . n 
A 1 5   THR 5   4   4   THR THR A . n 
A 1 6   ILE 6   5   5   ILE ILE A . n 
A 1 7   LYS 7   6   6   LYS LYS A . n 
A 1 8   VAL 8   7   7   VAL VAL A . n 
A 1 9   PHE 9   8   8   PHE PHE A . n 
A 1 10  THR 10  9   9   THR THR A . n 
A 1 11  THR 11  10  10  THR THR A . n 
A 1 12  VAL 12  11  11  VAL VAL A . n 
A 1 13  ASP 13  12  12  ASP ASP A . n 
A 1 14  ASN 14  13  13  ASN ASN A . n 
A 1 15  ILE 15  14  14  ILE ILE A . n 
A 1 16  ASN 16  15  15  ASN ASN A . n 
A 1 17  LEU 17  16  16  LEU LEU A . n 
A 1 18  HIS 18  17  17  HIS HIS A . n 
A 1 19  THR 19  18  18  THR THR A . n 
A 1 20  GLN 20  19  19  GLN GLN A . n 
A 1 21  VAL 21  20  20  VAL VAL A . n 
A 1 22  VAL 22  21  21  VAL VAL A . n 
A 1 23  ASP 23  22  22  ASP ASP A . n 
A 1 24  MET 24  23  23  MET MET A . n 
A 1 25  SER 25  24  24  SER SER A . n 
A 1 26  MET 26  25  25  MET MET A . n 
A 1 27  THR 27  26  26  THR THR A . n 
A 1 28  TYR 28  27  27  TYR TYR A . n 
A 1 29  GLY 29  28  28  GLY GLY A . n 
A 1 30  GLN 30  29  29  GLN GLN A . n 
A 1 31  GLN 31  30  30  GLN GLN A . n 
A 1 32  PHE 32  31  31  PHE PHE A . n 
A 1 33  GLY 33  32  32  GLY GLY A . n 
A 1 34  PRO 34  33  33  PRO PRO A . n 
A 1 35  THR 35  34  34  THR THR A . n 
A 1 36  TYR 36  35  35  TYR TYR A . n 
A 1 37  LEU 37  36  36  LEU LEU A . n 
A 1 38  ASP 38  37  37  ASP ASP A . n 
A 1 39  GLY 39  38  38  GLY GLY A . n 
A 1 40  ALA 40  39  39  ALA ALA A . n 
A 1 41  ASP 41  40  40  ASP ASP A . n 
A 1 42  VAL 42  41  41  VAL VAL A . n 
A 1 43  THR 43  42  42  THR THR A . n 
A 1 44  LYS 44  43  43  LYS LYS A . n 
A 1 45  ILE 45  44  44  ILE ILE A . n 
A 1 46  LYS 46  45  45  LYS LYS A . n 
A 1 47  PRO 47  46  46  PRO PRO A . n 
A 1 48  HIS 48  47  47  HIS HIS A . n 
A 1 49  ASN 49  48  48  ASN ASN A . n 
A 1 50  SER 50  49  49  SER SER A . n 
A 1 51  HIS 51  50  50  HIS HIS A . n 
A 1 52  GLU 52  51  51  GLU GLU A . n 
A 1 53  GLY 53  52  52  GLY GLY A . n 
A 1 54  LYS 54  53  53  LYS LYS A . n 
A 1 55  THR 55  54  54  THR THR A . n 
A 1 56  PHE 56  55  55  PHE PHE A . n 
A 1 57  TYR 57  56  56  TYR TYR A . n 
A 1 58  VAL 58  57  57  VAL VAL A . n 
A 1 59  LEU 59  58  58  LEU LEU A . n 
A 1 60  PRO 60  59  59  PRO PRO A . n 
A 1 61  ASN 61  60  60  ASN ASN A . n 
A 1 62  ASP 62  61  61  ASP ASP A . n 
A 1 63  ASP 63  62  62  ASP ASP A . n 
A 1 64  THR 64  63  63  THR THR A . n 
A 1 65  LEU 65  64  64  LEU LEU A . n 
A 1 66  ARG 66  65  65  ARG ARG A . n 
A 1 67  VAL 67  66  66  VAL VAL A . n 
A 1 68  GLU 68  67  67  GLU GLU A . n 
A 1 69  ALA 69  68  68  ALA ALA A . n 
A 1 70  PHE 70  69  69  PHE PHE A . n 
A 1 71  GLU 71  70  70  GLU GLU A . n 
A 1 72  TYR 72  71  71  TYR TYR A . n 
A 1 73  TYR 73  72  72  TYR TYR A . n 
A 1 74  HIS 74  73  73  HIS HIS A . n 
A 1 75  THR 75  74  74  THR THR A . n 
A 1 76  THR 76  75  75  THR THR A . n 
A 1 77  ASP 77  76  76  ASP ASP A . n 
A 1 78  PRO 78  77  77  PRO PRO A . n 
A 1 79  SER 79  78  78  SER SER A . n 
A 1 80  PHE 80  79  79  PHE PHE A . n 
A 1 81  LEU 81  80  80  LEU LEU A . n 
A 1 82  GLY 82  81  81  GLY GLY A . n 
A 1 83  ARG 83  82  82  ARG ARG A . n 
A 1 84  TYR 84  83  83  TYR TYR A . n 
A 1 85  MET 85  84  84  MET MET A . n 
A 1 86  SER 86  85  85  SER SER A . n 
A 1 87  ALA 87  86  86  ALA ALA A . n 
A 1 88  LEU 88  87  87  LEU LEU A . n 
A 1 89  ASN 89  88  88  ASN ASN A . n 
A 1 90  HIS 90  89  89  HIS HIS A . n 
A 1 91  THR 91  90  90  THR THR A . n 
A 1 92  LYS 92  91  91  LYS LYS A . n 
A 1 93  LYS 93  92  92  LYS LYS A . n 
A 1 94  TRP 94  93  93  TRP TRP A . n 
A 1 95  LYS 95  94  94  LYS LYS A . n 
A 1 96  TYR 96  95  95  TYR TYR A . n 
A 1 97  PRO 97  96  96  PRO PRO A . n 
A 1 98  GLN 98  97  97  GLN GLN A . n 
A 1 99  VAL 99  98  98  VAL VAL A . n 
A 1 100 ASN 100 99  99  ASN ASN A . n 
A 1 101 GLY 101 100 100 GLY GLY A . n 
A 1 102 LEU 102 101 101 LEU LEU A . n 
A 1 103 THR 103 102 102 THR THR A . n 
A 1 104 SER 104 103 103 SER SER A . n 
A 1 105 ILE 105 104 104 ILE ILE A . n 
A 1 106 LYS 106 105 105 LYS LYS A . n 
A 1 107 TRP 107 106 106 TRP TRP A . n 
A 1 108 ALA 108 107 107 ALA ALA A . n 
A 1 109 ASP 109 108 108 ASP ASP A . n 
A 1 110 ASN 110 109 109 ASN ASN A . n 
A 1 111 ASN 111 110 110 ASN ASN A . n 
A 1 112 SER 112 111 111 SER SER A . n 
A 1 113 TYR 113 112 112 TYR TYR A . n 
A 1 114 LEU 114 113 113 LEU LEU A . n 
A 1 115 ALA 115 114 114 ALA ALA A . n 
A 1 116 THR 116 115 115 THR THR A . n 
A 1 117 ALA 117 116 116 ALA ALA A . n 
A 1 118 LEU 118 117 117 LEU LEU A . n 
A 1 119 LEU 119 118 118 LEU LEU A . n 
A 1 120 THR 120 119 119 THR THR A . n 
A 1 121 LEU 121 120 120 LEU LEU A . n 
A 1 122 GLN 122 121 121 GLN GLN A . n 
A 1 123 GLN 123 122 122 GLN GLN A . n 
A 1 124 ILE 124 123 123 ILE ILE A . n 
A 1 125 GLU 125 124 124 GLU GLU A . n 
A 1 126 LEU 126 125 125 LEU LEU A . n 
A 1 127 LYS 127 126 126 LYS LYS A . n 
A 1 128 PHE 128 127 127 PHE PHE A . n 
A 1 129 ASN 129 128 128 ASN ASN A . n 
A 1 130 PRO 130 129 129 PRO PRO A . n 
A 1 131 PRO 131 130 130 PRO PRO A . n 
A 1 132 ALA 132 131 131 ALA ALA A . n 
A 1 133 LEU 133 132 132 LEU LEU A . n 
A 1 134 GLN 134 133 133 GLN GLN A . n 
A 1 135 ASP 135 134 134 ASP ASP A . n 
A 1 136 ALA 136 135 135 ALA ALA A . n 
A 1 137 TYR 137 136 136 TYR TYR A . n 
A 1 138 TYR 138 137 137 TYR TYR A . n 
A 1 139 ARG 139 138 138 ARG ARG A . n 
A 1 140 ALA 140 139 139 ALA ALA A . n 
A 1 141 ARG 141 140 140 ARG ARG A . n 
A 1 142 ALA 142 141 141 ALA ALA A . n 
A 1 143 GLY 143 142 142 GLY GLY A . n 
A 1 144 GLU 144 143 143 GLU GLU A . n 
A 1 145 ALA 145 144 144 ALA ALA A . n 
A 1 146 ALA 146 145 145 ALA ALA A . n 
A 1 147 ASN 147 146 146 ASN ASN A . n 
A 1 148 PHE 148 147 147 PHE PHE A . n 
A 1 149 CYS 149 148 148 CYS CYS A . n 
A 1 150 ALA 150 149 149 ALA ALA A . n 
A 1 151 LEU 151 150 150 LEU LEU A . n 
A 1 152 ILE 152 151 151 ILE ILE A . n 
A 1 153 LEU 153 152 152 LEU LEU A . n 
A 1 154 ALA 154 153 153 ALA ALA A . n 
A 1 155 TYR 155 154 154 TYR TYR A . n 
A 1 156 CYS 156 155 155 CYS CYS A . n 
A 1 157 ASN 157 156 156 ASN ASN A . n 
A 1 158 LYS 158 157 157 LYS LYS A . n 
A 1 159 THR 159 158 158 THR THR A . n 
A 1 160 VAL 160 159 159 VAL VAL A . n 
A 1 161 GLY 161 160 160 GLY GLY A . n 
A 1 162 GLU 162 161 161 GLU GLU A . n 
A 1 163 LEU 163 162 162 LEU LEU A . n 
A 1 164 GLY 164 163 163 GLY GLY A . n 
A 1 165 ASP 165 164 164 ASP ASP A . n 
A 1 166 VAL 166 165 165 VAL VAL A . n 
A 1 167 ARG 167 166 166 ARG ARG A . n 
A 1 168 GLU 168 167 167 GLU GLU A . n 
A 1 169 THR 169 168 168 THR THR A . n 
A 1 170 MET 170 169 169 MET MET A . n 
A 1 171 SER 171 170 170 SER SER A . n 
A 1 172 TYR 172 171 171 TYR TYR A . n 
A 1 173 LEU 173 172 172 LEU LEU A . n 
A 1 174 PHE 174 173 173 PHE PHE A . n 
A 1 175 GLN 175 174 174 GLN GLN A . n 
A 1 176 HIS 176 175 175 HIS HIS A . n 
A 1 177 ALA 177 176 176 ALA ALA A . n 
A 1 178 ASN 178 177 177 ASN ASN A . n 
A 1 179 LEU 179 178 178 LEU LEU A . n 
A 1 180 ASP 180 179 179 ASP ASP A . n 
A 1 181 SER 181 180 180 SER SER A . n 
A 1 182 CYS 182 181 181 CYS CYS A . n 
A 1 183 LYS 183 182 182 LYS LYS A . n 
A 1 184 ARG 184 183 183 ARG ARG A . n 
A 1 185 VAL 185 184 184 VAL VAL A . n 
A 1 186 LEU 186 185 185 LEU LEU A . n 
A 1 187 ASN 187 186 186 ASN ASN A . n 
A 1 188 VAL 188 187 187 VAL VAL A . n 
A 1 189 VAL 189 188 188 VAL VAL A . n 
A 1 190 CYS 190 189 ?   ?   ?   A . n 
A 1 191 LYS 191 190 ?   ?   ?   A . n 
A 1 192 THR 192 191 ?   ?   ?   A . n 
A 1 193 CYS 193 192 ?   ?   ?   A . n 
A 1 194 GLY 194 193 193 GLY GLY A . n 
A 1 195 GLN 195 194 194 GLN GLN A . n 
A 1 196 GLN 196 195 195 GLN GLN A . n 
A 1 197 GLN 197 196 196 GLN GLN A . n 
A 1 198 THR 198 197 197 THR THR A . n 
A 1 199 THR 199 198 198 THR THR A . n 
A 1 200 LEU 200 199 199 LEU LEU A . n 
A 1 201 LYS 201 200 200 LYS LYS A . n 
A 1 202 GLY 202 201 201 GLY GLY A . n 
A 1 203 VAL 203 202 202 VAL VAL A . n 
A 1 204 GLU 204 203 203 GLU GLU A . n 
A 1 205 ALA 205 204 204 ALA ALA A . n 
A 1 206 VAL 206 205 205 VAL VAL A . n 
A 1 207 MET 207 206 206 MET MET A . n 
A 1 208 TYR 208 207 207 TYR TYR A . n 
A 1 209 MET 209 208 208 MET MET A . n 
A 1 210 GLY 210 209 209 GLY GLY A . n 
A 1 211 THR 211 210 210 THR THR A . n 
A 1 212 LEU 212 211 211 LEU LEU A . n 
A 1 213 SER 213 212 212 SER SER A . n 
A 1 214 TYR 214 213 213 TYR TYR A . n 
A 1 215 GLU 215 214 214 GLU GLU A . n 
A 1 216 GLN 216 215 215 GLN GLN A . n 
A 1 217 PHE 217 216 216 PHE PHE A . n 
A 1 218 LYS 218 217 217 LYS LYS A . n 
A 1 219 LYS 219 218 218 LYS LYS A . n 
A 1 220 GLY 220 219 219 GLY GLY A . n 
A 1 221 VAL 221 220 220 VAL VAL A . n 
A 1 222 GLN 222 221 221 GLN GLN A . n 
A 1 223 ILE 223 222 222 ILE ILE A . n 
A 1 224 PRO 224 223 223 PRO PRO A . n 
A 1 225 CYS 225 224 ?   ?   ?   A . n 
A 1 226 THR 226 225 ?   ?   ?   A . n 
A 1 227 CYS 227 226 ?   ?   ?   A . n 
A 1 228 GLY 228 227 ?   ?   ?   A . n 
A 1 229 LYS 229 228 228 LYS LYS A . n 
A 1 230 GLN 230 229 229 GLN GLN A . n 
A 1 231 ALA 231 230 230 ALA ALA A . n 
A 1 232 THR 232 231 231 THR THR A . n 
A 1 233 LYS 233 232 232 LYS LYS A . n 
A 1 234 TYR 234 233 233 TYR TYR A . n 
A 1 235 LEU 235 234 234 LEU LEU A . n 
A 1 236 VAL 236 235 235 VAL VAL A . n 
A 1 237 GLN 237 236 236 GLN GLN A . n 
A 1 238 GLN 238 237 237 GLN GLN A . n 
A 1 239 GLU 239 238 238 GLU GLU A . n 
A 1 240 SER 240 239 239 SER SER A . n 
A 1 241 PRO 241 240 240 PRO PRO A . n 
A 1 242 PHE 242 241 241 PHE PHE A . n 
A 1 243 VAL 243 242 242 VAL VAL A . n 
A 1 244 MET 244 243 243 MET MET A . n 
A 1 245 MET 245 244 244 MET MET A . n 
A 1 246 SER 246 245 245 SER SER A . n 
A 1 247 ALA 247 246 246 ALA ALA A . n 
A 1 248 PRO 248 247 247 PRO PRO A . n 
A 1 249 PRO 249 248 248 PRO PRO A . n 
A 1 250 ALA 250 249 249 ALA ALA A . n 
A 1 251 GLN 251 250 250 GLN GLN A . n 
A 1 252 TYR 252 251 251 TYR TYR A . n 
A 1 253 GLU 253 252 252 GLU GLU A . n 
A 1 254 LEU 254 253 253 LEU LEU A . n 
A 1 255 LYS 255 254 254 LYS LYS A . n 
A 1 256 HIS 256 255 255 HIS HIS A . n 
A 1 257 GLY 257 256 256 GLY GLY A . n 
A 1 258 THR 258 257 257 THR THR A . n 
A 1 259 PHE 259 258 258 PHE PHE A . n 
A 1 260 THR 260 259 259 THR THR A . n 
A 1 261 CYS 261 260 260 CYS CYS A . n 
A 1 262 ALA 262 261 261 ALA ALA A . n 
A 1 263 SER 263 262 262 SER SER A . n 
A 1 264 GLU 264 263 263 GLU GLU A . n 
A 1 265 TYR 265 264 264 TYR TYR A . n 
A 1 266 THR 266 265 265 THR THR A . n 
A 1 267 GLY 267 266 266 GLY GLY A . n 
A 1 268 ASN 268 267 267 ASN ASN A . n 
A 1 269 TYR 269 268 268 TYR TYR A . n 
A 1 270 GLN 270 269 269 GLN GLN A . n 
A 1 271 CYS 271 270 270 CYS CYS A . n 
A 1 272 GLY 272 271 271 GLY GLY A . n 
A 1 273 HIS 273 272 272 HIS HIS A . n 
A 1 274 TYR 274 273 273 TYR TYR A . n 
A 1 275 LYS 275 274 274 LYS LYS A . n 
A 1 276 HIS 276 275 275 HIS HIS A . n 
A 1 277 ILE 277 276 276 ILE ILE A . n 
A 1 278 THR 278 277 277 THR THR A . n 
A 1 279 SER 279 278 278 SER SER A . n 
A 1 280 LYS 280 279 279 LYS LYS A . n 
A 1 281 GLU 281 280 280 GLU GLU A . n 
A 1 282 THR 282 281 281 THR THR A . n 
A 1 283 LEU 283 282 282 LEU LEU A . n 
A 1 284 TYR 284 283 283 TYR TYR A . n 
A 1 285 CYS 285 284 284 CYS CYS A . n 
A 1 286 ILE 286 285 285 ILE ILE A . n 
A 1 287 ASP 287 286 286 ASP ASP A . n 
A 1 288 GLY 288 287 287 GLY GLY A . n 
A 1 289 ALA 289 288 288 ALA ALA A . n 
A 1 290 LEU 290 289 289 LEU LEU A . n 
A 1 291 LEU 291 290 290 LEU LEU A . n 
A 1 292 THR 292 291 291 THR THR A . n 
A 1 293 LYS 293 292 292 LYS LYS A . n 
A 1 294 SER 294 293 293 SER SER A . n 
A 1 295 SER 295 294 294 SER SER A . n 
A 1 296 GLU 296 295 295 GLU GLU A . n 
A 1 297 TYR 297 296 296 TYR TYR A . n 
A 1 298 LYS 298 297 297 LYS LYS A . n 
A 1 299 GLY 299 298 298 GLY GLY A . n 
A 1 300 PRO 300 299 299 PRO PRO A . n 
A 1 301 ILE 301 300 300 ILE ILE A . n 
A 1 302 THR 302 301 301 THR THR A . n 
A 1 303 ASP 303 302 302 ASP ASP A . n 
A 1 304 VAL 304 303 303 VAL VAL A . n 
A 1 305 PHE 305 304 304 PHE PHE A . n 
A 1 306 TYR 306 305 305 TYR TYR A . n 
A 1 307 LYS 307 306 306 LYS LYS A . n 
A 1 308 GLU 308 307 307 GLU GLU A . n 
A 1 309 ASN 309 308 308 ASN ASN A . n 
A 1 310 SER 310 309 309 SER SER A . n 
A 1 311 TYR 311 310 310 TYR TYR A . n 
A 1 312 THR 312 311 311 THR THR A . n 
A 1 313 THR 313 312 312 THR THR A . n 
A 1 314 THR 314 313 313 THR THR A . n 
A 1 315 ILE 315 314 314 ILE ILE A . n 
A 1 316 LYS 316 315 ?   ?   ?   A . n 
B 1 1   GLY 1   0   0   GLY GLY B . n 
B 1 2   GLU 2   1   1   GLU GLU B . n 
B 1 3   VAL 3   2   2   VAL VAL B . n 
B 1 4   ARG 4   3   3   ARG ARG B . n 
B 1 5   THR 5   4   4   THR THR B . n 
B 1 6   ILE 6   5   5   ILE ILE B . n 
B 1 7   LYS 7   6   6   LYS LYS B . n 
B 1 8   VAL 8   7   7   VAL VAL B . n 
B 1 9   PHE 9   8   8   PHE PHE B . n 
B 1 10  THR 10  9   9   THR THR B . n 
B 1 11  THR 11  10  10  THR THR B . n 
B 1 12  VAL 12  11  11  VAL VAL B . n 
B 1 13  ASP 13  12  12  ASP ASP B . n 
B 1 14  ASN 14  13  13  ASN ASN B . n 
B 1 15  ILE 15  14  14  ILE ILE B . n 
B 1 16  ASN 16  15  15  ASN ASN B . n 
B 1 17  LEU 17  16  16  LEU LEU B . n 
B 1 18  HIS 18  17  17  HIS HIS B . n 
B 1 19  THR 19  18  18  THR THR B . n 
B 1 20  GLN 20  19  19  GLN GLN B . n 
B 1 21  VAL 21  20  20  VAL VAL B . n 
B 1 22  VAL 22  21  21  VAL VAL B . n 
B 1 23  ASP 23  22  22  ASP ASP B . n 
B 1 24  MET 24  23  23  MET MET B . n 
B 1 25  SER 25  24  24  SER SER B . n 
B 1 26  MET 26  25  25  MET MET B . n 
B 1 27  THR 27  26  26  THR THR B . n 
B 1 28  TYR 28  27  27  TYR TYR B . n 
B 1 29  GLY 29  28  28  GLY GLY B . n 
B 1 30  GLN 30  29  29  GLN GLN B . n 
B 1 31  GLN 31  30  30  GLN GLN B . n 
B 1 32  PHE 32  31  31  PHE PHE B . n 
B 1 33  GLY 33  32  32  GLY GLY B . n 
B 1 34  PRO 34  33  33  PRO PRO B . n 
B 1 35  THR 35  34  34  THR THR B . n 
B 1 36  TYR 36  35  35  TYR TYR B . n 
B 1 37  LEU 37  36  36  LEU LEU B . n 
B 1 38  ASP 38  37  37  ASP ASP B . n 
B 1 39  GLY 39  38  38  GLY GLY B . n 
B 1 40  ALA 40  39  39  ALA ALA B . n 
B 1 41  ASP 41  40  40  ASP ASP B . n 
B 1 42  VAL 42  41  41  VAL VAL B . n 
B 1 43  THR 43  42  42  THR THR B . n 
B 1 44  LYS 44  43  43  LYS LYS B . n 
B 1 45  ILE 45  44  44  ILE ILE B . n 
B 1 46  LYS 46  45  45  LYS LYS B . n 
B 1 47  PRO 47  46  46  PRO PRO B . n 
B 1 48  HIS 48  47  47  HIS HIS B . n 
B 1 49  ASN 49  48  48  ASN ASN B . n 
B 1 50  SER 50  49  49  SER SER B . n 
B 1 51  HIS 51  50  50  HIS HIS B . n 
B 1 52  GLU 52  51  51  GLU GLU B . n 
B 1 53  GLY 53  52  52  GLY GLY B . n 
B 1 54  LYS 54  53  53  LYS LYS B . n 
B 1 55  THR 55  54  54  THR THR B . n 
B 1 56  PHE 56  55  55  PHE PHE B . n 
B 1 57  TYR 57  56  56  TYR TYR B . n 
B 1 58  VAL 58  57  57  VAL VAL B . n 
B 1 59  LEU 59  58  58  LEU LEU B . n 
B 1 60  PRO 60  59  59  PRO PRO B . n 
B 1 61  ASN 61  60  60  ASN ASN B . n 
B 1 62  ASP 62  61  61  ASP ASP B . n 
B 1 63  ASP 63  62  62  ASP ASP B . n 
B 1 64  THR 64  63  63  THR THR B . n 
B 1 65  LEU 65  64  64  LEU LEU B . n 
B 1 66  ARG 66  65  65  ARG ARG B . n 
B 1 67  VAL 67  66  66  VAL VAL B . n 
B 1 68  GLU 68  67  67  GLU GLU B . n 
B 1 69  ALA 69  68  68  ALA ALA B . n 
B 1 70  PHE 70  69  69  PHE PHE B . n 
B 1 71  GLU 71  70  70  GLU GLU B . n 
B 1 72  TYR 72  71  71  TYR TYR B . n 
B 1 73  TYR 73  72  72  TYR TYR B . n 
B 1 74  HIS 74  73  73  HIS HIS B . n 
B 1 75  THR 75  74  74  THR THR B . n 
B 1 76  THR 76  75  75  THR THR B . n 
B 1 77  ASP 77  76  76  ASP ASP B . n 
B 1 78  PRO 78  77  77  PRO PRO B . n 
B 1 79  SER 79  78  78  SER SER B . n 
B 1 80  PHE 80  79  79  PHE PHE B . n 
B 1 81  LEU 81  80  80  LEU LEU B . n 
B 1 82  GLY 82  81  81  GLY GLY B . n 
B 1 83  ARG 83  82  82  ARG ARG B . n 
B 1 84  TYR 84  83  83  TYR TYR B . n 
B 1 85  MET 85  84  84  MET MET B . n 
B 1 86  SER 86  85  85  SER SER B . n 
B 1 87  ALA 87  86  86  ALA ALA B . n 
B 1 88  LEU 88  87  87  LEU LEU B . n 
B 1 89  ASN 89  88  88  ASN ASN B . n 
B 1 90  HIS 90  89  89  HIS HIS B . n 
B 1 91  THR 91  90  90  THR THR B . n 
B 1 92  LYS 92  91  91  LYS LYS B . n 
B 1 93  LYS 93  92  92  LYS LYS B . n 
B 1 94  TRP 94  93  93  TRP TRP B . n 
B 1 95  LYS 95  94  94  LYS LYS B . n 
B 1 96  TYR 96  95  95  TYR TYR B . n 
B 1 97  PRO 97  96  96  PRO PRO B . n 
B 1 98  GLN 98  97  97  GLN GLN B . n 
B 1 99  VAL 99  98  98  VAL VAL B . n 
B 1 100 ASN 100 99  99  ASN ASN B . n 
B 1 101 GLY 101 100 100 GLY GLY B . n 
B 1 102 LEU 102 101 101 LEU LEU B . n 
B 1 103 THR 103 102 102 THR THR B . n 
B 1 104 SER 104 103 103 SER SER B . n 
B 1 105 ILE 105 104 104 ILE ILE B . n 
B 1 106 LYS 106 105 105 LYS LYS B . n 
B 1 107 TRP 107 106 106 TRP TRP B . n 
B 1 108 ALA 108 107 107 ALA ALA B . n 
B 1 109 ASP 109 108 108 ASP ASP B . n 
B 1 110 ASN 110 109 109 ASN ASN B . n 
B 1 111 ASN 111 110 110 ASN ASN B . n 
B 1 112 SER 112 111 111 SER SER B . n 
B 1 113 TYR 113 112 112 TYR TYR B . n 
B 1 114 LEU 114 113 113 LEU LEU B . n 
B 1 115 ALA 115 114 114 ALA ALA B . n 
B 1 116 THR 116 115 115 THR THR B . n 
B 1 117 ALA 117 116 116 ALA ALA B . n 
B 1 118 LEU 118 117 117 LEU LEU B . n 
B 1 119 LEU 119 118 118 LEU LEU B . n 
B 1 120 THR 120 119 119 THR THR B . n 
B 1 121 LEU 121 120 120 LEU LEU B . n 
B 1 122 GLN 122 121 121 GLN GLN B . n 
B 1 123 GLN 123 122 122 GLN GLN B . n 
B 1 124 ILE 124 123 123 ILE ILE B . n 
B 1 125 GLU 125 124 124 GLU GLU B . n 
B 1 126 LEU 126 125 125 LEU LEU B . n 
B 1 127 LYS 127 126 126 LYS LYS B . n 
B 1 128 PHE 128 127 127 PHE PHE B . n 
B 1 129 ASN 129 128 128 ASN ASN B . n 
B 1 130 PRO 130 129 129 PRO PRO B . n 
B 1 131 PRO 131 130 130 PRO PRO B . n 
B 1 132 ALA 132 131 131 ALA ALA B . n 
B 1 133 LEU 133 132 132 LEU LEU B . n 
B 1 134 GLN 134 133 133 GLN GLN B . n 
B 1 135 ASP 135 134 134 ASP ASP B . n 
B 1 136 ALA 136 135 135 ALA ALA B . n 
B 1 137 TYR 137 136 136 TYR TYR B . n 
B 1 138 TYR 138 137 137 TYR TYR B . n 
B 1 139 ARG 139 138 138 ARG ARG B . n 
B 1 140 ALA 140 139 139 ALA ALA B . n 
B 1 141 ARG 141 140 140 ARG ARG B . n 
B 1 142 ALA 142 141 141 ALA ALA B . n 
B 1 143 GLY 143 142 142 GLY GLY B . n 
B 1 144 GLU 144 143 143 GLU GLU B . n 
B 1 145 ALA 145 144 144 ALA ALA B . n 
B 1 146 ALA 146 145 145 ALA ALA B . n 
B 1 147 ASN 147 146 146 ASN ASN B . n 
B 1 148 PHE 148 147 147 PHE PHE B . n 
B 1 149 CYS 149 148 148 CYS CYS B . n 
B 1 150 ALA 150 149 149 ALA ALA B . n 
B 1 151 LEU 151 150 150 LEU LEU B . n 
B 1 152 ILE 152 151 151 ILE ILE B . n 
B 1 153 LEU 153 152 152 LEU LEU B . n 
B 1 154 ALA 154 153 153 ALA ALA B . n 
B 1 155 TYR 155 154 154 TYR TYR B . n 
B 1 156 CYS 156 155 155 CYS CYS B . n 
B 1 157 ASN 157 156 156 ASN ASN B . n 
B 1 158 LYS 158 157 157 LYS LYS B . n 
B 1 159 THR 159 158 158 THR THR B . n 
B 1 160 VAL 160 159 159 VAL VAL B . n 
B 1 161 GLY 161 160 160 GLY GLY B . n 
B 1 162 GLU 162 161 161 GLU GLU B . n 
B 1 163 LEU 163 162 162 LEU LEU B . n 
B 1 164 GLY 164 163 163 GLY GLY B . n 
B 1 165 ASP 165 164 164 ASP ASP B . n 
B 1 166 VAL 166 165 165 VAL VAL B . n 
B 1 167 ARG 167 166 166 ARG ARG B . n 
B 1 168 GLU 168 167 167 GLU GLU B . n 
B 1 169 THR 169 168 168 THR THR B . n 
B 1 170 MET 170 169 169 MET MET B . n 
B 1 171 SER 171 170 170 SER SER B . n 
B 1 172 TYR 172 171 171 TYR TYR B . n 
B 1 173 LEU 173 172 172 LEU LEU B . n 
B 1 174 PHE 174 173 173 PHE PHE B . n 
B 1 175 GLN 175 174 174 GLN GLN B . n 
B 1 176 HIS 176 175 175 HIS HIS B . n 
B 1 177 ALA 177 176 176 ALA ALA B . n 
B 1 178 ASN 178 177 177 ASN ASN B . n 
B 1 179 LEU 179 178 178 LEU LEU B . n 
B 1 180 ASP 180 179 179 ASP ASP B . n 
B 1 181 SER 181 180 180 SER SER B . n 
B 1 182 CYS 182 181 181 CYS CYS B . n 
B 1 183 LYS 183 182 182 LYS LYS B . n 
B 1 184 ARG 184 183 183 ARG ARG B . n 
B 1 185 VAL 185 184 184 VAL VAL B . n 
B 1 186 LEU 186 185 185 LEU LEU B . n 
B 1 187 ASN 187 186 186 ASN ASN B . n 
B 1 188 VAL 188 187 187 VAL VAL B . n 
B 1 189 VAL 189 188 188 VAL VAL B . n 
B 1 190 CYS 190 189 189 CYS CYS B . n 
B 1 191 LYS 191 190 190 LYS LYS B . n 
B 1 192 THR 192 191 191 THR THR B . n 
B 1 193 CYS 193 192 192 CYS CYS B . n 
B 1 194 GLY 194 193 193 GLY GLY B . n 
B 1 195 GLN 195 194 194 GLN GLN B . n 
B 1 196 GLN 196 195 195 GLN GLN B . n 
B 1 197 GLN 197 196 196 GLN GLN B . n 
B 1 198 THR 198 197 197 THR THR B . n 
B 1 199 THR 199 198 198 THR THR B . n 
B 1 200 LEU 200 199 199 LEU LEU B . n 
B 1 201 LYS 201 200 200 LYS LYS B . n 
B 1 202 GLY 202 201 201 GLY GLY B . n 
B 1 203 VAL 203 202 202 VAL VAL B . n 
B 1 204 GLU 204 203 203 GLU GLU B . n 
B 1 205 ALA 205 204 204 ALA ALA B . n 
B 1 206 VAL 206 205 205 VAL VAL B . n 
B 1 207 MET 207 206 206 MET MET B . n 
B 1 208 TYR 208 207 207 TYR TYR B . n 
B 1 209 MET 209 208 208 MET MET B . n 
B 1 210 GLY 210 209 209 GLY GLY B . n 
B 1 211 THR 211 210 210 THR THR B . n 
B 1 212 LEU 212 211 211 LEU LEU B . n 
B 1 213 SER 213 212 212 SER SER B . n 
B 1 214 TYR 214 213 213 TYR TYR B . n 
B 1 215 GLU 215 214 214 GLU GLU B . n 
B 1 216 GLN 216 215 215 GLN GLN B . n 
B 1 217 PHE 217 216 216 PHE PHE B . n 
B 1 218 LYS 218 217 217 LYS LYS B . n 
B 1 219 LYS 219 218 218 LYS LYS B . n 
B 1 220 GLY 220 219 219 GLY GLY B . n 
B 1 221 VAL 221 220 220 VAL VAL B . n 
B 1 222 GLN 222 221 221 GLN GLN B . n 
B 1 223 ILE 223 222 222 ILE ILE B . n 
B 1 224 PRO 224 223 223 PRO PRO B . n 
B 1 225 CYS 225 224 224 CYS CYS B . n 
B 1 226 THR 226 225 225 THR THR B . n 
B 1 227 CYS 227 226 ?   ?   ?   B . n 
B 1 228 GLY 228 227 ?   ?   ?   B . n 
B 1 229 LYS 229 228 228 LYS LYS B . n 
B 1 230 GLN 230 229 229 GLN GLN B . n 
B 1 231 ALA 231 230 230 ALA ALA B . n 
B 1 232 THR 232 231 231 THR THR B . n 
B 1 233 LYS 233 232 232 LYS LYS B . n 
B 1 234 TYR 234 233 233 TYR TYR B . n 
B 1 235 LEU 235 234 234 LEU LEU B . n 
B 1 236 VAL 236 235 235 VAL VAL B . n 
B 1 237 GLN 237 236 236 GLN GLN B . n 
B 1 238 GLN 238 237 237 GLN GLN B . n 
B 1 239 GLU 239 238 238 GLU GLU B . n 
B 1 240 SER 240 239 239 SER SER B . n 
B 1 241 PRO 241 240 240 PRO PRO B . n 
B 1 242 PHE 242 241 241 PHE PHE B . n 
B 1 243 VAL 243 242 242 VAL VAL B . n 
B 1 244 MET 244 243 243 MET MET B . n 
B 1 245 MET 245 244 244 MET MET B . n 
B 1 246 SER 246 245 245 SER SER B . n 
B 1 247 ALA 247 246 246 ALA ALA B . n 
B 1 248 PRO 248 247 247 PRO PRO B . n 
B 1 249 PRO 249 248 248 PRO PRO B . n 
B 1 250 ALA 250 249 249 ALA ALA B . n 
B 1 251 GLN 251 250 250 GLN GLN B . n 
B 1 252 TYR 252 251 251 TYR TYR B . n 
B 1 253 GLU 253 252 252 GLU GLU B . n 
B 1 254 LEU 254 253 253 LEU LEU B . n 
B 1 255 LYS 255 254 254 LYS LYS B . n 
B 1 256 HIS 256 255 255 HIS HIS B . n 
B 1 257 GLY 257 256 256 GLY GLY B . n 
B 1 258 THR 258 257 257 THR THR B . n 
B 1 259 PHE 259 258 258 PHE PHE B . n 
B 1 260 THR 260 259 259 THR THR B . n 
B 1 261 CYS 261 260 260 CYS CYS B . n 
B 1 262 ALA 262 261 261 ALA ALA B . n 
B 1 263 SER 263 262 262 SER SER B . n 
B 1 264 GLU 264 263 263 GLU GLU B . n 
B 1 265 TYR 265 264 264 TYR TYR B . n 
B 1 266 THR 266 265 265 THR THR B . n 
B 1 267 GLY 267 266 266 GLY GLY B . n 
B 1 268 ASN 268 267 267 ASN ASN B . n 
B 1 269 TYR 269 268 268 TYR TYR B . n 
B 1 270 GLN 270 269 269 GLN GLN B . n 
B 1 271 CYS 271 270 270 CYS CYS B . n 
B 1 272 GLY 272 271 271 GLY GLY B . n 
B 1 273 HIS 273 272 272 HIS HIS B . n 
B 1 274 TYR 274 273 273 TYR TYR B . n 
B 1 275 LYS 275 274 274 LYS LYS B . n 
B 1 276 HIS 276 275 275 HIS HIS B . n 
B 1 277 ILE 277 276 276 ILE ILE B . n 
B 1 278 THR 278 277 277 THR THR B . n 
B 1 279 SER 279 278 278 SER SER B . n 
B 1 280 LYS 280 279 279 LYS LYS B . n 
B 1 281 GLU 281 280 280 GLU GLU B . n 
B 1 282 THR 282 281 281 THR THR B . n 
B 1 283 LEU 283 282 282 LEU LEU B . n 
B 1 284 TYR 284 283 283 TYR TYR B . n 
B 1 285 CYS 285 284 284 CYS CYS B . n 
B 1 286 ILE 286 285 285 ILE ILE B . n 
B 1 287 ASP 287 286 286 ASP ASP B . n 
B 1 288 GLY 288 287 287 GLY GLY B . n 
B 1 289 ALA 289 288 288 ALA ALA B . n 
B 1 290 LEU 290 289 289 LEU LEU B . n 
B 1 291 LEU 291 290 290 LEU LEU B . n 
B 1 292 THR 292 291 291 THR THR B . n 
B 1 293 LYS 293 292 292 LYS LYS B . n 
B 1 294 SER 294 293 293 SER SER B . n 
B 1 295 SER 295 294 294 SER SER B . n 
B 1 296 GLU 296 295 295 GLU GLU B . n 
B 1 297 TYR 297 296 296 TYR TYR B . n 
B 1 298 LYS 298 297 297 LYS LYS B . n 
B 1 299 GLY 299 298 298 GLY GLY B . n 
B 1 300 PRO 300 299 299 PRO PRO B . n 
B 1 301 ILE 301 300 300 ILE ILE B . n 
B 1 302 THR 302 301 301 THR THR B . n 
B 1 303 ASP 303 302 302 ASP ASP B . n 
B 1 304 VAL 304 303 303 VAL VAL B . n 
B 1 305 PHE 305 304 304 PHE PHE B . n 
B 1 306 TYR 306 305 305 TYR TYR B . n 
B 1 307 LYS 307 306 306 LYS LYS B . n 
B 1 308 GLU 308 307 307 GLU GLU B . n 
B 1 309 ASN 309 308 308 ASN ASN B . n 
B 1 310 SER 310 309 309 SER SER B . n 
B 1 311 TYR 311 310 310 TYR TYR B . n 
B 1 312 THR 312 311 311 THR THR B . n 
B 1 313 THR 313 312 312 THR THR B . n 
B 1 314 THR 314 313 313 THR THR B . n 
B 1 315 ILE 315 314 314 ILE ILE B . n 
B 1 316 LYS 316 315 ?   ?   ?   B . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        A1LZ8 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   A1LZ8 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
C 2 A1LZ8 1   401 500 A1LZ8 004 A . 
D 3 ZN    1   402 601 ZN    ZN  A . 
E 3 ZN    1   403 602 ZN    ZN  A . 
F 4 GOL   1   404 371 GOL   GLO A . 
G 4 GOL   1   405 372 GOL   GLO A . 
H 2 A1LZ8 1   401 500 A1LZ8 004 B . 
I 3 ZN    1   402 601 ZN    ZN  B . 
J 3 ZN    1   403 602 ZN    ZN  B . 
K 4 GOL   1   404 371 GOL   GLO B . 
L 4 GOL   1   405 372 GOL   GLO B . 
M 5 HOH   1   501 500 HOH   HOH A . 
M 5 HOH   2   502 311 HOH   HOH A . 
M 5 HOH   3   503 241 HOH   HOH A . 
M 5 HOH   4   504 444 HOH   HOH A . 
M 5 HOH   5   505 175 HOH   HOH A . 
M 5 HOH   6   506 463 HOH   HOH A . 
M 5 HOH   7   507 485 HOH   HOH A . 
M 5 HOH   8   508 4   HOH   HOH A . 
M 5 HOH   9   509 229 HOH   HOH A . 
M 5 HOH   10  510 333 HOH   HOH A . 
M 5 HOH   11  511 451 HOH   HOH A . 
M 5 HOH   12  512 135 HOH   HOH A . 
M 5 HOH   13  513 138 HOH   HOH A . 
M 5 HOH   14  514 475 HOH   HOH A . 
M 5 HOH   15  515 10  HOH   HOH A . 
M 5 HOH   16  516 525 HOH   HOH A . 
M 5 HOH   17  517 261 HOH   HOH A . 
M 5 HOH   18  518 198 HOH   HOH A . 
M 5 HOH   19  519 218 HOH   HOH A . 
M 5 HOH   20  520 75  HOH   HOH A . 
M 5 HOH   21  521 381 HOH   HOH A . 
M 5 HOH   22  522 310 HOH   HOH A . 
M 5 HOH   23  523 295 HOH   HOH A . 
M 5 HOH   24  524 125 HOH   HOH A . 
M 5 HOH   25  525 61  HOH   HOH A . 
M 5 HOH   26  526 222 HOH   HOH A . 
M 5 HOH   27  527 269 HOH   HOH A . 
M 5 HOH   28  528 102 HOH   HOH A . 
M 5 HOH   29  529 368 HOH   HOH A . 
M 5 HOH   30  530 127 HOH   HOH A . 
M 5 HOH   31  531 33  HOH   HOH A . 
M 5 HOH   32  532 87  HOH   HOH A . 
M 5 HOH   33  533 96  HOH   HOH A . 
M 5 HOH   34  534 319 HOH   HOH A . 
M 5 HOH   35  535 105 HOH   HOH A . 
M 5 HOH   36  536 342 HOH   HOH A . 
M 5 HOH   37  537 254 HOH   HOH A . 
M 5 HOH   38  538 280 HOH   HOH A . 
M 5 HOH   39  539 95  HOH   HOH A . 
M 5 HOH   40  540 65  HOH   HOH A . 
M 5 HOH   41  541 52  HOH   HOH A . 
M 5 HOH   42  542 115 HOH   HOH A . 
M 5 HOH   43  543 148 HOH   HOH A . 
M 5 HOH   44  544 423 HOH   HOH A . 
M 5 HOH   45  545 6   HOH   HOH A . 
M 5 HOH   46  546 363 HOH   HOH A . 
M 5 HOH   47  547 100 HOH   HOH A . 
M 5 HOH   48  548 82  HOH   HOH A . 
M 5 HOH   49  549 217 HOH   HOH A . 
M 5 HOH   50  550 177 HOH   HOH A . 
M 5 HOH   51  551 48  HOH   HOH A . 
M 5 HOH   52  552 38  HOH   HOH A . 
M 5 HOH   53  553 83  HOH   HOH A . 
M 5 HOH   54  554 92  HOH   HOH A . 
M 5 HOH   55  555 106 HOH   HOH A . 
M 5 HOH   56  556 114 HOH   HOH A . 
M 5 HOH   57  557 187 HOH   HOH A . 
M 5 HOH   58  558 15  HOH   HOH A . 
M 5 HOH   59  559 247 HOH   HOH A . 
M 5 HOH   60  560 263 HOH   HOH A . 
M 5 HOH   61  561 234 HOH   HOH A . 
M 5 HOH   62  562 193 HOH   HOH A . 
M 5 HOH   63  563 461 HOH   HOH A . 
M 5 HOH   64  564 113 HOH   HOH A . 
M 5 HOH   65  565 2   HOH   HOH A . 
M 5 HOH   66  566 28  HOH   HOH A . 
M 5 HOH   67  567 29  HOH   HOH A . 
M 5 HOH   68  568 470 HOH   HOH A . 
M 5 HOH   69  569 174 HOH   HOH A . 
M 5 HOH   70  570 47  HOH   HOH A . 
M 5 HOH   71  571 103 HOH   HOH A . 
M 5 HOH   72  572 321 HOH   HOH A . 
M 5 HOH   73  573 62  HOH   HOH A . 
M 5 HOH   74  574 17  HOH   HOH A . 
M 5 HOH   75  575 166 HOH   HOH A . 
M 5 HOH   76  576 98  HOH   HOH A . 
M 5 HOH   77  577 27  HOH   HOH A . 
M 5 HOH   78  578 192 HOH   HOH A . 
M 5 HOH   79  579 364 HOH   HOH A . 
M 5 HOH   80  580 53  HOH   HOH A . 
M 5 HOH   81  581 8   HOH   HOH A . 
M 5 HOH   82  582 279 HOH   HOH A . 
M 5 HOH   83  583 161 HOH   HOH A . 
M 5 HOH   84  584 154 HOH   HOH A . 
M 5 HOH   85  585 246 HOH   HOH A . 
M 5 HOH   86  586 50  HOH   HOH A . 
M 5 HOH   87  587 130 HOH   HOH A . 
M 5 HOH   88  588 159 HOH   HOH A . 
M 5 HOH   89  589 216 HOH   HOH A . 
M 5 HOH   90  590 392 HOH   HOH A . 
M 5 HOH   91  591 268 HOH   HOH A . 
M 5 HOH   92  592 152 HOH   HOH A . 
M 5 HOH   93  593 339 HOH   HOH A . 
M 5 HOH   94  594 94  HOH   HOH A . 
M 5 HOH   95  595 182 HOH   HOH A . 
M 5 HOH   96  596 332 HOH   HOH A . 
M 5 HOH   97  597 1   HOH   HOH A . 
M 5 HOH   98  598 172 HOH   HOH A . 
M 5 HOH   99  599 205 HOH   HOH A . 
M 5 HOH   100 600 3   HOH   HOH A . 
M 5 HOH   101 601 214 HOH   HOH A . 
M 5 HOH   102 602 43  HOH   HOH A . 
M 5 HOH   103 603 344 HOH   HOH A . 
M 5 HOH   104 604 535 HOH   HOH A . 
M 5 HOH   105 605 264 HOH   HOH A . 
M 5 HOH   106 606 23  HOH   HOH A . 
M 5 HOH   107 607 284 HOH   HOH A . 
M 5 HOH   108 608 32  HOH   HOH A . 
M 5 HOH   109 609 71  HOH   HOH A . 
M 5 HOH   110 610 397 HOH   HOH A . 
M 5 HOH   111 611 55  HOH   HOH A . 
M 5 HOH   112 612 260 HOH   HOH A . 
M 5 HOH   113 613 54  HOH   HOH A . 
M 5 HOH   114 614 357 HOH   HOH A . 
M 5 HOH   115 615 42  HOH   HOH A . 
M 5 HOH   116 616 526 HOH   HOH A . 
M 5 HOH   117 617 385 HOH   HOH A . 
M 5 HOH   118 618 474 HOH   HOH A . 
M 5 HOH   119 619 126 HOH   HOH A . 
M 5 HOH   120 620 79  HOH   HOH A . 
M 5 HOH   121 621 63  HOH   HOH A . 
M 5 HOH   122 622 196 HOH   HOH A . 
M 5 HOH   123 623 176 HOH   HOH A . 
M 5 HOH   124 624 391 HOH   HOH A . 
M 5 HOH   125 625 120 HOH   HOH A . 
M 5 HOH   126 626 375 HOH   HOH A . 
M 5 HOH   127 627 81  HOH   HOH A . 
M 5 HOH   128 628 356 HOH   HOH A . 
M 5 HOH   129 629 362 HOH   HOH A . 
M 5 HOH   130 630 134 HOH   HOH A . 
M 5 HOH   131 631 361 HOH   HOH A . 
M 5 HOH   132 632 460 HOH   HOH A . 
M 5 HOH   133 633 13  HOH   HOH A . 
M 5 HOH   134 634 22  HOH   HOH A . 
M 5 HOH   135 635 465 HOH   HOH A . 
M 5 HOH   136 636 170 HOH   HOH A . 
M 5 HOH   137 637 265 HOH   HOH A . 
M 5 HOH   138 638 165 HOH   HOH A . 
M 5 HOH   139 639 429 HOH   HOH A . 
M 5 HOH   140 640 199 HOH   HOH A . 
M 5 HOH   141 641 157 HOH   HOH A . 
M 5 HOH   142 642 323 HOH   HOH A . 
M 5 HOH   143 643 226 HOH   HOH A . 
M 5 HOH   144 644 305 HOH   HOH A . 
M 5 HOH   145 645 412 HOH   HOH A . 
M 5 HOH   146 646 306 HOH   HOH A . 
M 5 HOH   147 647 89  HOH   HOH A . 
M 5 HOH   148 648 30  HOH   HOH A . 
M 5 HOH   149 649 124 HOH   HOH A . 
M 5 HOH   150 650 473 HOH   HOH A . 
M 5 HOH   151 651 215 HOH   HOH A . 
M 5 HOH   152 652 282 HOH   HOH A . 
M 5 HOH   153 653 164 HOH   HOH A . 
M 5 HOH   154 654 250 HOH   HOH A . 
M 5 HOH   155 655 249 HOH   HOH A . 
M 5 HOH   156 656 142 HOH   HOH A . 
M 5 HOH   157 657 51  HOH   HOH A . 
M 5 HOH   158 658 327 HOH   HOH A . 
M 5 HOH   159 659 292 HOH   HOH A . 
M 5 HOH   160 660 330 HOH   HOH A . 
M 5 HOH   161 661 494 HOH   HOH A . 
M 5 HOH   162 662 512 HOH   HOH A . 
M 5 HOH   163 663 147 HOH   HOH A . 
M 5 HOH   164 664 9   HOH   HOH A . 
M 5 HOH   165 665 5   HOH   HOH A . 
M 5 HOH   166 666 85  HOH   HOH A . 
M 5 HOH   167 667 149 HOH   HOH A . 
M 5 HOH   168 668 409 HOH   HOH A . 
M 5 HOH   169 669 219 HOH   HOH A . 
M 5 HOH   170 670 406 HOH   HOH A . 
M 5 HOH   171 671 77  HOH   HOH A . 
M 5 HOH   172 672 308 HOH   HOH A . 
M 5 HOH   173 673 352 HOH   HOH A . 
M 5 HOH   174 674 90  HOH   HOH A . 
M 5 HOH   175 675 496 HOH   HOH A . 
M 5 HOH   176 676 370 HOH   HOH A . 
M 5 HOH   177 677 160 HOH   HOH A . 
M 5 HOH   178 678 84  HOH   HOH A . 
M 5 HOH   179 679 350 HOH   HOH A . 
M 5 HOH   180 680 454 HOH   HOH A . 
M 5 HOH   181 681 74  HOH   HOH A . 
M 5 HOH   182 682 248 HOH   HOH A . 
M 5 HOH   183 683 169 HOH   HOH A . 
M 5 HOH   184 684 86  HOH   HOH A . 
M 5 HOH   185 685 108 HOH   HOH A . 
M 5 HOH   186 686 155 HOH   HOH A . 
M 5 HOH   187 687 527 HOH   HOH A . 
M 5 HOH   188 688 36  HOH   HOH A . 
M 5 HOH   189 689 273 HOH   HOH A . 
M 5 HOH   190 690 212 HOH   HOH A . 
M 5 HOH   191 691 244 HOH   HOH A . 
M 5 HOH   192 692 203 HOH   HOH A . 
M 5 HOH   193 693 359 HOH   HOH A . 
M 5 HOH   194 694 441 HOH   HOH A . 
M 5 HOH   195 695 337 HOH   HOH A . 
M 5 HOH   196 696 258 HOH   HOH A . 
M 5 HOH   197 697 131 HOH   HOH A . 
M 5 HOH   198 698 21  HOH   HOH A . 
M 5 HOH   199 699 336 HOH   HOH A . 
M 5 HOH   200 700 438 HOH   HOH A . 
M 5 HOH   201 701 56  HOH   HOH A . 
M 5 HOH   202 702 378 HOH   HOH A . 
M 5 HOH   203 703 298 HOH   HOH A . 
M 5 HOH   204 704 313 HOH   HOH A . 
M 5 HOH   205 705 283 HOH   HOH A . 
M 5 HOH   206 706 358 HOH   HOH A . 
M 5 HOH   207 707 101 HOH   HOH A . 
M 5 HOH   208 708 210 HOH   HOH A . 
M 5 HOH   209 709 458 HOH   HOH A . 
M 5 HOH   210 710 278 HOH   HOH A . 
M 5 HOH   211 711 67  HOH   HOH A . 
M 5 HOH   212 712 487 HOH   HOH A . 
M 5 HOH   213 713 402 HOH   HOH A . 
M 5 HOH   214 714 189 HOH   HOH A . 
M 5 HOH   215 715 539 HOH   HOH A . 
M 5 HOH   216 716 419 HOH   HOH A . 
M 5 HOH   217 717 348 HOH   HOH A . 
M 5 HOH   218 718 252 HOH   HOH A . 
M 5 HOH   219 719 285 HOH   HOH A . 
M 5 HOH   220 720 301 HOH   HOH A . 
M 5 HOH   221 721 499 HOH   HOH A . 
M 5 HOH   222 722 322 HOH   HOH A . 
M 5 HOH   223 723 408 HOH   HOH A . 
M 5 HOH   224 724 231 HOH   HOH A . 
M 5 HOH   225 725 528 HOH   HOH A . 
M 5 HOH   226 726 167 HOH   HOH A . 
M 5 HOH   227 727 413 HOH   HOH A . 
M 5 HOH   228 728 341 HOH   HOH A . 
M 5 HOH   229 729 505 HOH   HOH A . 
M 5 HOH   230 730 287 HOH   HOH A . 
M 5 HOH   231 731 24  HOH   HOH A . 
M 5 HOH   232 732 251 HOH   HOH A . 
M 5 HOH   233 733 372 HOH   HOH A . 
M 5 HOH   234 734 146 HOH   HOH A . 
M 5 HOH   235 735 455 HOH   HOH A . 
M 5 HOH   236 736 211 HOH   HOH A . 
M 5 HOH   237 737 299 HOH   HOH A . 
M 5 HOH   238 738 449 HOH   HOH A . 
M 5 HOH   239 739 436 HOH   HOH A . 
M 5 HOH   240 740 238 HOH   HOH A . 
M 5 HOH   241 741 483 HOH   HOH A . 
M 5 HOH   242 742 266 HOH   HOH A . 
M 5 HOH   243 743 188 HOH   HOH A . 
M 5 HOH   244 744 456 HOH   HOH A . 
M 5 HOH   245 745 511 HOH   HOH A . 
M 5 HOH   246 746 324 HOH   HOH A . 
M 5 HOH   247 747 425 HOH   HOH A . 
M 5 HOH   248 748 448 HOH   HOH A . 
M 5 HOH   249 749 415 HOH   HOH A . 
M 5 HOH   250 750 257 HOH   HOH A . 
M 5 HOH   251 751 446 HOH   HOH A . 
M 5 HOH   252 752 491 HOH   HOH A . 
M 5 HOH   253 753 469 HOH   HOH A . 
M 5 HOH   254 754 420 HOH   HOH A . 
M 5 HOH   255 755 190 HOH   HOH A . 
M 5 HOH   256 756 522 HOH   HOH A . 
M 5 HOH   257 757 481 HOH   HOH A . 
M 5 HOH   258 758 435 HOH   HOH A . 
M 5 HOH   259 759 376 HOH   HOH A . 
M 5 HOH   260 760 467 HOH   HOH A . 
M 5 HOH   261 761 472 HOH   HOH A . 
M 5 HOH   262 762 519 HOH   HOH A . 
M 5 HOH   263 763 533 HOH   HOH A . 
M 5 HOH   264 764 141 HOH   HOH A . 
M 5 HOH   265 765 316 HOH   HOH A . 
M 5 HOH   266 766 502 HOH   HOH A . 
M 5 HOH   267 767 400 HOH   HOH A . 
M 5 HOH   268 768 227 HOH   HOH A . 
M 5 HOH   269 769 118 HOH   HOH A . 
M 5 HOH   270 770 428 HOH   HOH A . 
M 5 HOH   271 771 380 HOH   HOH A . 
M 5 HOH   272 772 492 HOH   HOH A . 
M 5 HOH   273 773 325 HOH   HOH A . 
M 5 HOH   274 774 365 HOH   HOH A . 
M 5 HOH   275 775 442 HOH   HOH A . 
M 5 HOH   276 776 498 HOH   HOH A . 
M 5 HOH   277 777 432 HOH   HOH A . 
M 5 HOH   278 778 501 HOH   HOH A . 
M 5 HOH   279 779 267 HOH   HOH A . 
M 5 HOH   280 780 320 HOH   HOH A . 
M 5 HOH   281 781 202 HOH   HOH A . 
M 5 HOH   282 782 489 HOH   HOH A . 
M 5 HOH   283 783 520 HOH   HOH A . 
M 5 HOH   284 784 281 HOH   HOH A . 
M 5 HOH   285 785 99  HOH   HOH A . 
M 5 HOH   286 786 440 HOH   HOH A . 
M 5 HOH   287 787 516 HOH   HOH A . 
M 5 HOH   288 788 288 HOH   HOH A . 
M 5 HOH   289 789 294 HOH   HOH A . 
M 5 HOH   290 790 163 HOH   HOH A . 
M 5 HOH   291 791 447 HOH   HOH A . 
N 5 HOH   1   501 296 HOH   HOH B . 
N 5 HOH   2   502 464 HOH   HOH B . 
N 5 HOH   3   503 490 HOH   HOH B . 
N 5 HOH   4   504 443 HOH   HOH B . 
N 5 HOH   5   505 437 HOH   HOH B . 
N 5 HOH   6   506 213 HOH   HOH B . 
N 5 HOH   7   507 384 HOH   HOH B . 
N 5 HOH   8   508 482 HOH   HOH B . 
N 5 HOH   9   509 12  HOH   HOH B . 
N 5 HOH   10  510 466 HOH   HOH B . 
N 5 HOH   11  511 304 HOH   HOH B . 
N 5 HOH   12  512 183 HOH   HOH B . 
N 5 HOH   13  513 80  HOH   HOH B . 
N 5 HOH   14  514 107 HOH   HOH B . 
N 5 HOH   15  515 427 HOH   HOH B . 
N 5 HOH   16  516 277 HOH   HOH B . 
N 5 HOH   17  517 377 HOH   HOH B . 
N 5 HOH   18  518 354 HOH   HOH B . 
N 5 HOH   19  519 7   HOH   HOH B . 
N 5 HOH   20  520 315 HOH   HOH B . 
N 5 HOH   21  521 110 HOH   HOH B . 
N 5 HOH   22  522 11  HOH   HOH B . 
N 5 HOH   23  523 46  HOH   HOH B . 
N 5 HOH   24  524 340 HOH   HOH B . 
N 5 HOH   25  525 14  HOH   HOH B . 
N 5 HOH   26  526 312 HOH   HOH B . 
N 5 HOH   27  527 133 HOH   HOH B . 
N 5 HOH   28  528 518 HOH   HOH B . 
N 5 HOH   29  529 109 HOH   HOH B . 
N 5 HOH   30  530 329 HOH   HOH B . 
N 5 HOH   31  531 271 HOH   HOH B . 
N 5 HOH   32  532 393 HOH   HOH B . 
N 5 HOH   33  533 345 HOH   HOH B . 
N 5 HOH   34  534 521 HOH   HOH B . 
N 5 HOH   35  535 532 HOH   HOH B . 
N 5 HOH   36  536 16  HOH   HOH B . 
N 5 HOH   37  537 140 HOH   HOH B . 
N 5 HOH   38  538 70  HOH   HOH B . 
N 5 HOH   39  539 208 HOH   HOH B . 
N 5 HOH   40  540 457 HOH   HOH B . 
N 5 HOH   41  541 396 HOH   HOH B . 
N 5 HOH   42  542 434 HOH   HOH B . 
N 5 HOH   43  543 497 HOH   HOH B . 
N 5 HOH   44  544 69  HOH   HOH B . 
N 5 HOH   45  545 66  HOH   HOH B . 
N 5 HOH   46  546 41  HOH   HOH B . 
N 5 HOH   47  547 91  HOH   HOH B . 
N 5 HOH   48  548 207 HOH   HOH B . 
N 5 HOH   49  549 371 HOH   HOH B . 
N 5 HOH   50  550 26  HOH   HOH B . 
N 5 HOH   51  551 68  HOH   HOH B . 
N 5 HOH   52  552 221 HOH   HOH B . 
N 5 HOH   53  553 240 HOH   HOH B . 
N 5 HOH   54  554 57  HOH   HOH B . 
N 5 HOH   55  555 386 HOH   HOH B . 
N 5 HOH   56  556 137 HOH   HOH B . 
N 5 HOH   57  557 191 HOH   HOH B . 
N 5 HOH   58  558 153 HOH   HOH B . 
N 5 HOH   59  559 276 HOH   HOH B . 
N 5 HOH   60  560 407 HOH   HOH B . 
N 5 HOH   61  561 346 HOH   HOH B . 
N 5 HOH   62  562 314 HOH   HOH B . 
N 5 HOH   63  563 508 HOH   HOH B . 
N 5 HOH   64  564 25  HOH   HOH B . 
N 5 HOH   65  565 233 HOH   HOH B . 
N 5 HOH   66  566 403 HOH   HOH B . 
N 5 HOH   67  567 72  HOH   HOH B . 
N 5 HOH   68  568 59  HOH   HOH B . 
N 5 HOH   69  569 129 HOH   HOH B . 
N 5 HOH   70  570 44  HOH   HOH B . 
N 5 HOH   71  571 185 HOH   HOH B . 
N 5 HOH   72  572 40  HOH   HOH B . 
N 5 HOH   73  573 88  HOH   HOH B . 
N 5 HOH   74  574 78  HOH   HOH B . 
N 5 HOH   75  575 64  HOH   HOH B . 
N 5 HOH   76  576 145 HOH   HOH B . 
N 5 HOH   77  577 223 HOH   HOH B . 
N 5 HOH   78  578 349 HOH   HOH B . 
N 5 HOH   79  579 538 HOH   HOH B . 
N 5 HOH   80  580 286 HOH   HOH B . 
N 5 HOH   81  581 293 HOH   HOH B . 
N 5 HOH   82  582 399 HOH   HOH B . 
N 5 HOH   83  583 307 HOH   HOH B . 
N 5 HOH   84  584 117 HOH   HOH B . 
N 5 HOH   85  585 421 HOH   HOH B . 
N 5 HOH   86  586 509 HOH   HOH B . 
N 5 HOH   87  587 37  HOH   HOH B . 
N 5 HOH   88  588 97  HOH   HOH B . 
N 5 HOH   89  589 317 HOH   HOH B . 
N 5 HOH   90  590 476 HOH   HOH B . 
N 5 HOH   91  591 453 HOH   HOH B . 
N 5 HOH   92  592 49  HOH   HOH B . 
N 5 HOH   93  593 275 HOH   HOH B . 
N 5 HOH   94  594 262 HOH   HOH B . 
N 5 HOH   95  595 326 HOH   HOH B . 
N 5 HOH   96  596 116 HOH   HOH B . 
N 5 HOH   97  597 132 HOH   HOH B . 
N 5 HOH   98  598 338 HOH   HOH B . 
N 5 HOH   99  599 58  HOH   HOH B . 
N 5 HOH   100 600 220 HOH   HOH B . 
N 5 HOH   101 601 45  HOH   HOH B . 
N 5 HOH   102 602 245 HOH   HOH B . 
N 5 HOH   103 603 162 HOH   HOH B . 
N 5 HOH   104 604 259 HOH   HOH B . 
N 5 HOH   105 605 382 HOH   HOH B . 
N 5 HOH   106 606 360 HOH   HOH B . 
N 5 HOH   107 607 524 HOH   HOH B . 
N 5 HOH   108 608 112 HOH   HOH B . 
N 5 HOH   109 609 122 HOH   HOH B . 
N 5 HOH   110 610 477 HOH   HOH B . 
N 5 HOH   111 611 395 HOH   HOH B . 
N 5 HOH   112 612 411 HOH   HOH B . 
N 5 HOH   113 613 31  HOH   HOH B . 
N 5 HOH   114 614 513 HOH   HOH B . 
N 5 HOH   115 615 495 HOH   HOH B . 
N 5 HOH   116 616 514 HOH   HOH B . 
N 5 HOH   117 617 418 HOH   HOH B . 
N 5 HOH   118 618 270 HOH   HOH B . 
N 5 HOH   119 619 510 HOH   HOH B . 
N 5 HOH   120 620 173 HOH   HOH B . 
N 5 HOH   121 621 73  HOH   HOH B . 
N 5 HOH   122 622 209 HOH   HOH B . 
N 5 HOH   123 623 180 HOH   HOH B . 
N 5 HOH   124 624 256 HOH   HOH B . 
N 5 HOH   125 625 401 HOH   HOH B . 
N 5 HOH   126 626 459 HOH   HOH B . 
N 5 HOH   127 627 19  HOH   HOH B . 
N 5 HOH   128 628 60  HOH   HOH B . 
N 5 HOH   129 629 136 HOH   HOH B . 
N 5 HOH   130 630 39  HOH   HOH B . 
N 5 HOH   131 631 139 HOH   HOH B . 
N 5 HOH   132 632 506 HOH   HOH B . 
N 5 HOH   133 633 144 HOH   HOH B . 
N 5 HOH   134 634 20  HOH   HOH B . 
N 5 HOH   135 635 390 HOH   HOH B . 
N 5 HOH   136 636 537 HOH   HOH B . 
N 5 HOH   137 637 35  HOH   HOH B . 
N 5 HOH   138 638 158 HOH   HOH B . 
N 5 HOH   139 639 433 HOH   HOH B . 
N 5 HOH   140 640 515 HOH   HOH B . 
N 5 HOH   141 641 104 HOH   HOH B . 
N 5 HOH   142 642 347 HOH   HOH B . 
N 5 HOH   143 643 253 HOH   HOH B . 
N 5 HOH   144 644 373 HOH   HOH B . 
N 5 HOH   145 645 237 HOH   HOH B . 
N 5 HOH   146 646 150 HOH   HOH B . 
N 5 HOH   147 647 224 HOH   HOH B . 
N 5 HOH   148 648 121 HOH   HOH B . 
N 5 HOH   149 649 243 HOH   HOH B . 
N 5 HOH   150 650 394 HOH   HOH B . 
N 5 HOH   151 651 290 HOH   HOH B . 
N 5 HOH   152 652 128 HOH   HOH B . 
N 5 HOH   153 653 156 HOH   HOH B . 
N 5 HOH   154 654 343 HOH   HOH B . 
N 5 HOH   155 655 389 HOH   HOH B . 
N 5 HOH   156 656 383 HOH   HOH B . 
N 5 HOH   157 657 351 HOH   HOH B . 
N 5 HOH   158 658 255 HOH   HOH B . 
N 5 HOH   159 659 417 HOH   HOH B . 
N 5 HOH   160 660 232 HOH   HOH B . 
N 5 HOH   161 661 93  HOH   HOH B . 
N 5 HOH   162 662 388 HOH   HOH B . 
N 5 HOH   163 663 291 HOH   HOH B . 
N 5 HOH   164 664 297 HOH   HOH B . 
N 5 HOH   165 665 328 HOH   HOH B . 
N 5 HOH   166 666 462 HOH   HOH B . 
N 5 HOH   167 667 387 HOH   HOH B . 
N 5 HOH   168 668 168 HOH   HOH B . 
N 5 HOH   169 669 111 HOH   HOH B . 
N 5 HOH   170 670 228 HOH   HOH B . 
N 5 HOH   171 671 309 HOH   HOH B . 
N 5 HOH   172 672 416 HOH   HOH B . 
N 5 HOH   173 673 179 HOH   HOH B . 
N 5 HOH   174 674 18  HOH   HOH B . 
N 5 HOH   175 675 236 HOH   HOH B . 
N 5 HOH   176 676 151 HOH   HOH B . 
N 5 HOH   177 677 369 HOH   HOH B . 
N 5 HOH   178 678 274 HOH   HOH B . 
N 5 HOH   179 679 76  HOH   HOH B . 
N 5 HOH   180 680 204 HOH   HOH B . 
N 5 HOH   181 681 523 HOH   HOH B . 
N 5 HOH   182 682 186 HOH   HOH B . 
N 5 HOH   183 683 201 HOH   HOH B . 
N 5 HOH   184 684 379 HOH   HOH B . 
N 5 HOH   185 685 414 HOH   HOH B . 
N 5 HOH   186 686 430 HOH   HOH B . 
N 5 HOH   187 687 480 HOH   HOH B . 
N 5 HOH   188 688 355 HOH   HOH B . 
N 5 HOH   189 689 353 HOH   HOH B . 
N 5 HOH   190 690 471 HOH   HOH B . 
N 5 HOH   191 691 178 HOH   HOH B . 
N 5 HOH   192 692 424 HOH   HOH B . 
N 5 HOH   193 693 452 HOH   HOH B . 
N 5 HOH   194 694 405 HOH   HOH B . 
N 5 HOH   195 695 119 HOH   HOH B . 
N 5 HOH   196 696 426 HOH   HOH B . 
N 5 HOH   197 697 335 HOH   HOH B . 
N 5 HOH   198 698 334 HOH   HOH B . 
N 5 HOH   199 699 239 HOH   HOH B . 
N 5 HOH   200 700 225 HOH   HOH B . 
N 5 HOH   201 701 439 HOH   HOH B . 
N 5 HOH   202 702 197 HOH   HOH B . 
N 5 HOH   203 703 195 HOH   HOH B . 
N 5 HOH   204 704 450 HOH   HOH B . 
N 5 HOH   205 705 331 HOH   HOH B . 
N 5 HOH   206 706 517 HOH   HOH B . 
N 5 HOH   207 707 422 HOH   HOH B . 
N 5 HOH   208 708 503 HOH   HOH B . 
N 5 HOH   209 709 504 HOH   HOH B . 
N 5 HOH   210 710 289 HOH   HOH B . 
N 5 HOH   211 711 507 HOH   HOH B . 
N 5 HOH   212 712 34  HOH   HOH B . 
N 5 HOH   213 713 445 HOH   HOH B . 
N 5 HOH   214 714 529 HOH   HOH B . 
N 5 HOH   215 715 300 HOH   HOH B . 
N 5 HOH   216 716 367 HOH   HOH B . 
N 5 HOH   217 717 493 HOH   HOH B . 
N 5 HOH   218 718 272 HOH   HOH B . 
N 5 HOH   219 719 123 HOH   HOH B . 
N 5 HOH   220 720 531 HOH   HOH B . 
N 5 HOH   221 721 484 HOH   HOH B . 
N 5 HOH   222 722 534 HOH   HOH B . 
N 5 HOH   223 723 431 HOH   HOH B . 
N 5 HOH   224 724 468 HOH   HOH B . 
N 5 HOH   225 725 486 HOH   HOH B . 
N 5 HOH   226 726 230 HOH   HOH B . 
N 5 HOH   227 727 302 HOH   HOH B . 
N 5 HOH   228 728 536 HOH   HOH B . 
N 5 HOH   229 729 235 HOH   HOH B . 
N 5 HOH   230 730 171 HOH   HOH B . 
N 5 HOH   231 731 303 HOH   HOH B . 
N 5 HOH   232 732 398 HOH   HOH B . 
N 5 HOH   233 733 181 HOH   HOH B . 
N 5 HOH   234 734 478 HOH   HOH B . 
N 5 HOH   235 735 318 HOH   HOH B . 
N 5 HOH   236 736 194 HOH   HOH B . 
N 5 HOH   237 737 404 HOH   HOH B . 
N 5 HOH   238 738 479 HOH   HOH B . 
N 5 HOH   239 739 184 HOH   HOH B . 
N 5 HOH   240 740 488 HOH   HOH B . 
N 5 HOH   241 741 206 HOH   HOH B . 
N 5 HOH   242 742 200 HOH   HOH B . 
N 5 HOH   243 743 366 HOH   HOH B . 
N 5 HOH   244 744 143 HOH   HOH B . 
N 5 HOH   245 745 374 HOH   HOH B . 
N 5 HOH   246 746 530 HOH   HOH B . 
N 5 HOH   247 747 242 HOH   HOH B . 
N 5 HOH   248 748 410 HOH   HOH B . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 A LYS 228 ? CG  ? A LYS 229 CG  
2  1 Y 1 A LYS 228 ? CD  ? A LYS 229 CD  
3  1 Y 1 A LYS 228 ? CE  ? A LYS 229 CE  
4  1 Y 1 A LYS 228 ? NZ  ? A LYS 229 NZ  
5  1 Y 1 B TYR 137 ? CG  ? B TYR 138 CG  
6  1 Y 1 B TYR 137 ? CD1 ? B TYR 138 CD1 
7  1 Y 1 B TYR 137 ? CD2 ? B TYR 138 CD2 
8  1 Y 1 B TYR 137 ? CE1 ? B TYR 138 CE1 
9  1 Y 1 B TYR 137 ? CE2 ? B TYR 138 CE2 
10 1 Y 1 B TYR 137 ? CZ  ? B TYR 138 CZ  
11 1 Y 1 B TYR 137 ? OH  ? B TYR 138 OH  
12 1 Y 1 B LYS 190 ? CG  ? B LYS 191 CG  
13 1 Y 1 B LYS 190 ? CD  ? B LYS 191 CD  
14 1 Y 1 B LYS 190 ? CE  ? B LYS 191 CE  
15 1 Y 1 B LYS 190 ? NZ  ? B LYS 191 NZ  
16 1 Y 1 B THR 191 ? OG1 ? B THR 192 OG1 
17 1 Y 1 B THR 191 ? CG2 ? B THR 192 CG2 
18 1 Y 1 B CYS 192 ? SG  ? B CYS 193 SG  
19 1 Y 1 B THR 225 ? OG1 ? B THR 226 OG1 
20 1 Y 1 B THR 225 ? CG2 ? B THR 226 CG2 
21 1 Y 1 B LYS 228 ? CG  ? B LYS 229 CG  
22 1 Y 1 B LYS 228 ? CD  ? B LYS 229 CD  
23 1 Y 1 B LYS 228 ? CE  ? B LYS 229 CE  
24 1 Y 1 B LYS 228 ? NZ  ? B LYS 229 NZ  
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX  ? ? ? '(1.20.1_4487: ???)' 1 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? XDS     ? ? ? .                    2 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? autoXDS ? ? ? .                    3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASES  ? ? ? .                    4 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   99.24 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8YX5 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     46.870 
_cell.length_a_esd                 ? 
_cell.length_b                     144.970 
_cell.length_b_esd                 ? 
_cell.length_c                     60.100 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        4 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8YX5 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                4 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1 21 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8YX5 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.82 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          56.41 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              7.6 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '0.03 M Citric acid, 0.07 M BIS-TRIS propane)/pH 7.6, 20% w/v PEG 3350' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            298 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER X 9M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2023-10-20 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.97918 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'SSRF BEAMLINE BL19U1' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.97918 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   BL19U1 
_diffrn_source.pdbx_synchrotron_site       SSRF 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       8YX5 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              1.74 
_reflns.d_resolution_low                               25.32 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     154756 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           96.00 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                2.0 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          15.19 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   1 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              ? 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    1.74 
_reflns_shell.d_res_low                                     1.802 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           1.70 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             11536 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               2.0 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.933 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               ? 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8YX5 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            1.74 
_refine.ls_d_res_low                             25.32 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     77589 
_refine.ls_number_reflns_R_free                  3898 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    96.04 
_refine.ls_percent_reflns_R_free                 5.02 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.1716 
_refine.ls_R_factor_R_free                       0.1946 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1704 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.37 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      7CJM 
_refine.pdbx_stereochemistry_target_values       ML 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.10 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.90 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 21.20 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.17 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       1.74 
_refine_hist.d_res_low                        25.32 
_refine_hist.number_atoms_solvent             539 
_refine_hist.number_atoms_total               5542 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        4907 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         96 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.013  ? ?   ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 1.524  ? ?   ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 12.957 ? 722 ? f_dihedral_angle_d ? ? 
'X-RAY DIFFRACTION' ? 0.180  ? 776 ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.025  ? 888 ? f_plane_restr      ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 1.74 1.76  . . 102 1887 70.00  . . . . 0.2900 . . . . . . . . . . . 0.3248 
'X-RAY DIFFRACTION' 1.76 1.78  . . 105 1986 73.00  . . . . 0.2833 . . . . . . . . . . . 0.2952 
'X-RAY DIFFRACTION' 1.78 1.81  . . 126 2181 79.00  . . . . 0.2492 . . . . . . . . . . . 0.2965 
'X-RAY DIFFRACTION' 1.81 1.83  . . 111 2337 86.00  . . . . 0.2504 . . . . . . . . . . . 0.2640 
'X-RAY DIFFRACTION' 1.83 1.86  . . 122 2478 90.00  . . . . 0.2420 . . . . . . . . . . . 0.2896 
'X-RAY DIFFRACTION' 1.86 1.89  . . 147 2559 94.00  . . . . 0.2302 . . . . . . . . . . . 0.2476 
'X-RAY DIFFRACTION' 1.89 1.92  . . 136 2693 99.00  . . . . 0.2176 . . . . . . . . . . . 0.2223 
'X-RAY DIFFRACTION' 1.92 1.95  . . 141 2741 99.00  . . . . 0.2059 . . . . . . . . . . . 0.2221 
'X-RAY DIFFRACTION' 1.95 1.98  . . 156 2688 100.00 . . . . 0.1928 . . . . . . . . . . . 0.2054 
'X-RAY DIFFRACTION' 1.98 2.02  . . 148 2756 100.00 . . . . 0.1767 . . . . . . . . . . . 0.2564 
'X-RAY DIFFRACTION' 2.02 2.05  . . 135 2764 100.00 . . . . 0.1719 . . . . . . . . . . . 0.1958 
'X-RAY DIFFRACTION' 2.05 2.10  . . 156 2693 100.00 . . . . 0.1566 . . . . . . . . . . . 0.1865 
'X-RAY DIFFRACTION' 2.10 2.14  . . 142 2775 100.00 . . . . 0.1680 . . . . . . . . . . . 0.1993 
'X-RAY DIFFRACTION' 2.14 2.19  . . 163 2713 100.00 . . . . 0.1687 . . . . . . . . . . . 0.1938 
'X-RAY DIFFRACTION' 2.19 2.25  . . 138 2743 100.00 . . . . 0.1705 . . . . . . . . . . . 0.2109 
'X-RAY DIFFRACTION' 2.25 2.31  . . 123 2746 100.00 . . . . 0.1716 . . . . . . . . . . . 0.2345 
'X-RAY DIFFRACTION' 2.31 2.38  . . 162 2724 100.00 . . . . 0.1741 . . . . . . . . . . . 0.2157 
'X-RAY DIFFRACTION' 2.38 2.45  . . 153 2725 100.00 . . . . 0.1695 . . . . . . . . . . . 0.1986 
'X-RAY DIFFRACTION' 2.45 2.54  . . 132 2749 100.00 . . . . 0.1673 . . . . . . . . . . . 0.2009 
'X-RAY DIFFRACTION' 2.54 2.64  . . 151 2749 100.00 . . . . 0.1652 . . . . . . . . . . . 0.1880 
'X-RAY DIFFRACTION' 2.64 2.76  . . 147 2741 100.00 . . . . 0.1627 . . . . . . . . . . . 0.1732 
'X-RAY DIFFRACTION' 2.76 2.91  . . 139 2747 100.00 . . . . 0.1644 . . . . . . . . . . . 0.1939 
'X-RAY DIFFRACTION' 2.91 3.09  . . 140 2744 100.00 . . . . 0.1659 . . . . . . . . . . . 0.1890 
'X-RAY DIFFRACTION' 3.09 3.33  . . 125 2781 100.00 . . . . 0.1603 . . . . . . . . . . . 0.1937 
'X-RAY DIFFRACTION' 3.33 3.66  . . 149 2724 100.00 . . . . 0.1524 . . . . . . . . . . . 0.1742 
'X-RAY DIFFRACTION' 3.66 4.19  . . 156 2731 100.00 . . . . 0.1450 . . . . . . . . . . . 0.1480 
'X-RAY DIFFRACTION' 4.19 5.27  . . 139 2767 100.00 . . . . 0.1444 . . . . . . . . . . . 0.1519 
'X-RAY DIFFRACTION' 5.27 25.32 . . 154 2769 99.00  . . . . 0.1995 . . . . . . . . . . . 0.2312 
# 
_struct.entry_id                     8YX5 
_struct.title                        'Crystal Structure of SARS CoV-2 Papain-like Protease PLpro-C111S in Complex with GZNL-P35' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8YX5 
_struct_keywords.text            'SARS CoV-2, PAPAIN-LIKE PROTEINASE, NSP3, HYDROLASE' 
_struct_keywords.pdbx_keywords   HYDROLASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 2 ? 
D N N 3 ? 
E N N 3 ? 
F N N 4 ? 
G N N 4 ? 
H N N 2 ? 
I N N 3 ? 
J N N 3 ? 
K N N 4 ? 
L N N 4 ? 
M N N 5 ? 
N N N 5 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    R1AB_SARS2 
_struct_ref.pdbx_db_accession          P0DTD1 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;EVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTLRVEAFEYYHTTDPSFL
GRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVG
ELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESP
FVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVFYKENSYTTTIK
;
_struct_ref.pdbx_align_begin           1564 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8YX5 A 2 ? 316 ? P0DTD1 1564 ? 1878 ? 1 315 
2 1 8YX5 B 2 ? 316 ? P0DTD1 1564 ? 1878 ? 1 315 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8YX5 GLY A 1   ? UNP P0DTD1 ?   ?    'expression tag'      0   1 
1 8YX5 SER A 112 ? UNP P0DTD1 CYS 1674 'engineered mutation' 111 2 
2 8YX5 GLY B 1   ? UNP P0DTD1 ?   ?    'expression tag'      0   3 
2 8YX5 SER B 112 ? UNP P0DTD1 CYS 1674 'engineered mutation' 111 4 
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 author_defined_assembly ? monomeric 1 
2 author_defined_assembly ? monomeric 1 
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 1 A,C,D,E,F,G,M 
2 1 B,H,I,J,K,L,N 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 THR A 27  ? GLY A 33  ? THR A 26  GLY A 32  1 ? 7  
HELX_P HELX_P2  AA2 HIS A 48  ? GLU A 52  ? HIS A 47  GLU A 51  5 ? 5  
HELX_P HELX_P3  AA3 ASP A 62  ? HIS A 74  ? ASP A 61  HIS A 73  1 ? 13 
HELX_P HELX_P4  AA4 SER A 79  ? LYS A 92  ? SER A 78  LYS A 91  1 ? 14 
HELX_P HELX_P5  AA5 ASN A 111 ? GLN A 122 ? ASN A 110 GLN A 121 1 ? 12 
HELX_P HELX_P6  AA6 PRO A 130 ? ALA A 142 ? PRO A 129 ALA A 141 1 ? 13 
HELX_P HELX_P7  AA7 ALA A 145 ? CYS A 156 ? ALA A 144 CYS A 155 1 ? 12 
HELX_P HELX_P8  AA8 ASP A 165 ? GLN A 175 ? ASP A 164 GLN A 174 1 ? 11 
HELX_P HELX_P9  AA9 VAL A 203 ? ALA A 205 ? VAL A 202 ALA A 204 5 ? 3  
HELX_P HELX_P10 AB1 SER A 213 ? GLY A 220 ? SER A 212 GLY A 219 1 ? 8  
HELX_P HELX_P11 AB2 THR B 27  ? GLY B 33  ? THR B 26  GLY B 32  1 ? 7  
HELX_P HELX_P12 AB3 HIS B 48  ? GLU B 52  ? HIS B 47  GLU B 51  5 ? 5  
HELX_P HELX_P13 AB4 ASP B 62  ? HIS B 74  ? ASP B 61  HIS B 73  1 ? 13 
HELX_P HELX_P14 AB5 SER B 79  ? LYS B 92  ? SER B 78  LYS B 91  1 ? 14 
HELX_P HELX_P15 AB6 ASN B 111 ? GLN B 122 ? ASN B 110 GLN B 121 1 ? 12 
HELX_P HELX_P16 AB7 PRO B 130 ? ALA B 142 ? PRO B 129 ALA B 141 1 ? 13 
HELX_P HELX_P17 AB8 ALA B 145 ? ASN B 157 ? ALA B 144 ASN B 156 1 ? 13 
HELX_P HELX_P18 AB9 ASP B 165 ? GLN B 175 ? ASP B 164 GLN B 174 1 ? 11 
HELX_P HELX_P19 AC1 VAL B 203 ? ALA B 205 ? VAL B 202 ALA B 204 5 ? 3  
HELX_P HELX_P20 AC2 SER B 213 ? GLY B 220 ? SER B 212 GLY B 219 1 ? 8  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
metalc1 metalc ? ? B CYS 190 SG ? ? ? 1_555 I ZN . ZN ? ? B CYS 189 B ZN 402 1_555 ? ? ? ? ? ? ? 2.337 ? ? 
metalc2 metalc ? ? B CYS 225 SG ? ? ? 1_555 I ZN . ZN ? ? B CYS 224 B ZN 402 1_555 ? ? ? ? ? ? ? 2.353 ? ? 
# 
_struct_conn_type.id          metalc 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
_pdbx_struct_conn_angle.id                    1 
_pdbx_struct_conn_angle.ptnr1_label_atom_id   SG 
_pdbx_struct_conn_angle.ptnr1_label_alt_id    ? 
_pdbx_struct_conn_angle.ptnr1_label_asym_id   B 
_pdbx_struct_conn_angle.ptnr1_label_comp_id   CYS 
_pdbx_struct_conn_angle.ptnr1_label_seq_id    190 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id    ? 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id    B 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id    CYS 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id     189 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code    ? 
_pdbx_struct_conn_angle.ptnr1_symmetry        1_555 
_pdbx_struct_conn_angle.ptnr2_label_atom_id   ZN 
_pdbx_struct_conn_angle.ptnr2_label_alt_id    ? 
_pdbx_struct_conn_angle.ptnr2_label_asym_id   I 
_pdbx_struct_conn_angle.ptnr2_label_comp_id   ZN 
_pdbx_struct_conn_angle.ptnr2_label_seq_id    . 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id    ? 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id    B 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id    ZN 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id     402 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code    ? 
_pdbx_struct_conn_angle.ptnr2_symmetry        1_555 
_pdbx_struct_conn_angle.ptnr3_label_atom_id   SG 
_pdbx_struct_conn_angle.ptnr3_label_alt_id    ? 
_pdbx_struct_conn_angle.ptnr3_label_asym_id   B 
_pdbx_struct_conn_angle.ptnr3_label_comp_id   CYS 
_pdbx_struct_conn_angle.ptnr3_label_seq_id    225 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id    ? 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id    B 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id    CYS 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id     224 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code    ? 
_pdbx_struct_conn_angle.ptnr3_symmetry        1_555 
_pdbx_struct_conn_angle.value                 122.5 
_pdbx_struct_conn_angle.value_esd             ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 5 ? 
AA2 ? 2 ? 
AA3 ? 4 ? 
AA4 ? 4 ? 
AA5 ? 7 ? 
AA6 ? 5 ? 
AA7 ? 2 ? 
AA8 ? 4 ? 
AA9 ? 4 ? 
AB1 ? 7 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? parallel      
AA1 3 4 ? anti-parallel 
AA1 4 5 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA5 1 2 ? parallel      
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA5 4 5 ? anti-parallel 
AA5 5 6 ? anti-parallel 
AA5 6 7 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? parallel      
AA6 3 4 ? anti-parallel 
AA6 4 5 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AB1 1 2 ? parallel      
AB1 2 3 ? anti-parallel 
AB1 3 4 ? anti-parallel 
AB1 4 5 ? anti-parallel 
AB1 5 6 ? anti-parallel 
AB1 6 7 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 HIS A 18  ? ASP A 23  ? HIS A 17  ASP A 22  
AA1 2 THR A 5   ? THR A 11  ? THR A 4   THR A 10  
AA1 3 THR A 55  ? VAL A 58  ? THR A 54  VAL A 57  
AA1 4 THR A 35  ? LEU A 37  ? THR A 34  LEU A 36  
AA1 5 ALA A 40  ? ASP A 41  ? ALA A 39  ASP A 40  
AA2 1 GLN A 98  ? VAL A 99  ? GLN A 97  VAL A 98  
AA2 2 LEU A 102 ? THR A 103 ? LEU A 101 THR A 102 
AA3 1 GLN A 196 ? LYS A 201 ? GLN A 195 LYS A 200 
AA3 2 LYS A 183 ? VAL A 189 ? LYS A 182 VAL A 188 
AA3 3 ALA A 231 ? GLU A 239 ? ALA A 230 GLU A 238 
AA3 4 VAL A 221 ? ILE A 223 ? VAL A 220 ILE A 222 
AA4 1 GLN A 196 ? LYS A 201 ? GLN A 195 LYS A 200 
AA4 2 LYS A 183 ? VAL A 189 ? LYS A 182 VAL A 188 
AA4 3 ALA A 231 ? GLU A 239 ? ALA A 230 GLU A 238 
AA4 4 SER A 310 ? THR A 312 ? SER A 309 THR A 311 
AA5 1 MET A 207 ? MET A 209 ? MET A 206 MET A 208 
AA5 2 PHE A 242 ? LEU A 254 ? PHE A 241 LEU A 253 
AA5 3 TYR A 297 ? LYS A 307 ? TYR A 296 LYS A 306 
AA5 4 CYS A 261 ? THR A 266 ? CYS A 260 THR A 265 
AA5 5 HIS A 273 ? SER A 279 ? HIS A 272 SER A 278 
AA5 6 LEU A 283 ? ASP A 287 ? LEU A 282 ASP A 286 
AA5 7 LEU A 290 ? SER A 294 ? LEU A 289 SER A 293 
AA6 1 HIS B 18  ? ASP B 23  ? HIS B 17  ASP B 22  
AA6 2 THR B 5   ? THR B 11  ? THR B 4   THR B 10  
AA6 3 THR B 55  ? VAL B 58  ? THR B 54  VAL B 57  
AA6 4 THR B 35  ? LEU B 37  ? THR B 34  LEU B 36  
AA6 5 ALA B 40  ? ASP B 41  ? ALA B 39  ASP B 40  
AA7 1 GLN B 98  ? VAL B 99  ? GLN B 97  VAL B 98  
AA7 2 LEU B 102 ? THR B 103 ? LEU B 101 THR B 102 
AA8 1 GLY B 194 ? LYS B 201 ? GLY B 193 LYS B 200 
AA8 2 LYS B 183 ? CYS B 190 ? LYS B 182 CYS B 189 
AA8 3 GLN B 230 ? GLU B 239 ? GLN B 229 GLU B 238 
AA8 4 VAL B 221 ? PRO B 224 ? VAL B 220 PRO B 223 
AA9 1 GLY B 194 ? LYS B 201 ? GLY B 193 LYS B 200 
AA9 2 LYS B 183 ? CYS B 190 ? LYS B 182 CYS B 189 
AA9 3 GLN B 230 ? GLU B 239 ? GLN B 229 GLU B 238 
AA9 4 SER B 310 ? THR B 312 ? SER B 309 THR B 311 
AB1 1 MET B 207 ? MET B 209 ? MET B 206 MET B 208 
AB1 2 PHE B 242 ? LEU B 254 ? PHE B 241 LEU B 253 
AB1 3 TYR B 297 ? LYS B 307 ? TYR B 296 LYS B 306 
AB1 4 CYS B 261 ? THR B 266 ? CYS B 260 THR B 265 
AB1 5 HIS B 273 ? SER B 279 ? HIS B 272 SER B 278 
AB1 6 LEU B 283 ? ASP B 287 ? LEU B 282 ASP B 286 
AB1 7 LEU B 290 ? SER B 294 ? LEU B 289 SER B 293 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O GLN A 20  ? O GLN A 19  N VAL A 8   ? N VAL A 7   
AA1 2 3 N PHE A 9   ? N PHE A 8   O PHE A 56  ? O PHE A 55  
AA1 3 4 O TYR A 57  ? O TYR A 56  N TYR A 36  ? N TYR A 35  
AA1 4 5 N LEU A 37  ? N LEU A 36  O ALA A 40  ? O ALA A 39  
AA2 1 2 N VAL A 99  ? N VAL A 98  O LEU A 102 ? O LEU A 101 
AA3 1 2 O LEU A 200 ? O LEU A 199 N ARG A 184 ? N ARG A 183 
AA3 2 3 N VAL A 185 ? N VAL A 184 O VAL A 236 ? O VAL A 235 
AA3 3 4 O LYS A 233 ? O LYS A 232 N VAL A 221 ? N VAL A 220 
AA4 1 2 O LEU A 200 ? O LEU A 199 N ARG A 184 ? N ARG A 183 
AA4 2 3 N VAL A 185 ? N VAL A 184 O VAL A 236 ? O VAL A 235 
AA4 3 4 N GLN A 238 ? N GLN A 237 O TYR A 311 ? O TYR A 310 
AA5 1 2 N TYR A 208 ? N TYR A 207 O SER A 246 ? O SER A 245 
AA5 2 3 N MET A 245 ? N MET A 244 O VAL A 304 ? O VAL A 303 
AA5 3 4 O PHE A 305 ? O PHE A 304 N CYS A 261 ? N CYS A 260 
AA5 4 5 N ALA A 262 ? N ALA A 261 O ILE A 277 ? O ILE A 276 
AA5 5 6 N HIS A 276 ? N HIS A 275 O ILE A 286 ? O ILE A 285 
AA5 6 7 N ASP A 287 ? N ASP A 286 O LEU A 290 ? O LEU A 289 
AA6 1 2 O GLN B 20  ? O GLN B 19  N VAL B 8   ? N VAL B 7   
AA6 2 3 N PHE B 9   ? N PHE B 8   O PHE B 56  ? O PHE B 55  
AA6 3 4 O TYR B 57  ? O TYR B 56  N TYR B 36  ? N TYR B 35  
AA6 4 5 N LEU B 37  ? N LEU B 36  O ALA B 40  ? O ALA B 39  
AA7 1 2 N VAL B 99  ? N VAL B 98  O LEU B 102 ? O LEU B 101 
AA8 1 2 O GLY B 194 ? O GLY B 193 N CYS B 190 ? N CYS B 189 
AA8 2 3 N VAL B 189 ? N VAL B 188 O THR B 232 ? O THR B 231 
AA8 3 4 O ALA B 231 ? O ALA B 230 N ILE B 223 ? N ILE B 222 
AA9 1 2 O GLY B 194 ? O GLY B 193 N CYS B 190 ? N CYS B 189 
AA9 2 3 N VAL B 189 ? N VAL B 188 O THR B 232 ? O THR B 231 
AA9 3 4 N GLN B 238 ? N GLN B 237 O TYR B 311 ? O TYR B 310 
AB1 1 2 N TYR B 208 ? N TYR B 207 O SER B 246 ? O SER B 245 
AB1 2 3 N MET B 245 ? N MET B 244 O VAL B 304 ? O VAL B 303 
AB1 3 4 O PHE B 305 ? O PHE B 304 N CYS B 261 ? N CYS B 260 
AB1 4 5 N ALA B 262 ? N ALA B 261 O ILE B 277 ? O ILE B 276 
AB1 5 6 N HIS B 276 ? N HIS B 275 O ILE B 286 ? O ILE B 285 
AB1 6 7 N CYS B 285 ? N CYS B 284 O THR B 292 ? O THR B 291 
# 
_pdbx_entry_details.entry_id                   8YX5 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 ASN A 13  ? ? 58.67   19.81   
2 1 SER A 103 ? ? -109.93 -168.76 
3 1 CYS A 270 ? ? -144.90 28.75   
4 1 LYS A 279 ? ? -126.43 -117.99 
5 1 ASN A 308 ? ? -139.24 -63.26  
6 1 SER B 103 ? ? -111.35 -168.72 
7 1 LYS B 279 ? ? -127.32 -116.19 
8 1 ASN B 308 ? ? -139.39 -64.83  
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A CYS 189 ? A CYS 190 
2  1 Y 1 A LYS 190 ? A LYS 191 
3  1 Y 1 A THR 191 ? A THR 192 
4  1 Y 1 A CYS 192 ? A CYS 193 
5  1 Y 1 A CYS 224 ? A CYS 225 
6  1 Y 1 A THR 225 ? A THR 226 
7  1 Y 1 A CYS 226 ? A CYS 227 
8  1 Y 1 A GLY 227 ? A GLY 228 
9  1 Y 1 A LYS 315 ? A LYS 316 
10 1 Y 1 B CYS 226 ? B CYS 227 
11 1 Y 1 B GLY 227 ? B GLY 228 
12 1 Y 1 B LYS 315 ? B LYS 316 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
A1LZ8 C02  C  N N 1   
A1LZ8 C03  C  Y N 2   
A1LZ8 C04  C  Y N 3   
A1LZ8 C05  C  Y N 4   
A1LZ8 C07  C  N N 5   
A1LZ8 C08  C  N R 6   
A1LZ8 C09  C  N N 7   
A1LZ8 C10  C  N S 8   
A1LZ8 C11  C  N N 9   
A1LZ8 C13  C  Y N 10  
A1LZ8 C14  C  Y N 11  
A1LZ8 C15  C  Y N 12  
A1LZ8 C16  C  N N 13  
A1LZ8 C18  C  N N 14  
A1LZ8 C19  C  Y N 15  
A1LZ8 C20  C  Y N 16  
A1LZ8 C21  C  Y N 17  
A1LZ8 C22  C  Y N 18  
A1LZ8 C23  C  Y N 19  
A1LZ8 C24  C  Y N 20  
A1LZ8 C25  C  Y N 21  
A1LZ8 C26  C  Y N 22  
A1LZ8 C27  C  Y N 23  
A1LZ8 C28  C  Y N 24  
A1LZ8 C29  C  N N 25  
A1LZ8 C32  C  N N 26  
A1LZ8 C33  C  N N 27  
A1LZ8 C34  C  N N 28  
A1LZ8 N06  N  N N 29  
A1LZ8 N12  N  N N 30  
A1LZ8 N17  N  N N 31  
A1LZ8 N31  N  N N 32  
A1LZ8 O01  O  N N 33  
A1LZ8 O30  O  N N 34  
A1LZ8 H1   H  N N 35  
A1LZ8 H2   H  N N 36  
A1LZ8 H3   H  N N 37  
A1LZ8 H4   H  N N 38  
A1LZ8 H5   H  N N 39  
A1LZ8 H6   H  N N 40  
A1LZ8 H7   H  N N 41  
A1LZ8 H8   H  N N 42  
A1LZ8 H9   H  N N 43  
A1LZ8 H10  H  N N 44  
A1LZ8 H11  H  N N 45  
A1LZ8 H12  H  N N 46  
A1LZ8 H13  H  N N 47  
A1LZ8 H14  H  N N 48  
A1LZ8 H15  H  N N 49  
A1LZ8 H16  H  N N 50  
A1LZ8 H17  H  N N 51  
A1LZ8 H18  H  N N 52  
A1LZ8 H19  H  N N 53  
A1LZ8 H20  H  N N 54  
A1LZ8 H21  H  N N 55  
A1LZ8 H22  H  N N 56  
A1LZ8 H23  H  N N 57  
A1LZ8 H24  H  N N 58  
A1LZ8 H25  H  N N 59  
A1LZ8 H26  H  N N 60  
A1LZ8 H27  H  N N 61  
A1LZ8 H28  H  N N 62  
ALA   N    N  N N 63  
ALA   CA   C  N S 64  
ALA   C    C  N N 65  
ALA   O    O  N N 66  
ALA   CB   C  N N 67  
ALA   OXT  O  N N 68  
ALA   H    H  N N 69  
ALA   H2   H  N N 70  
ALA   HA   H  N N 71  
ALA   HB1  H  N N 72  
ALA   HB2  H  N N 73  
ALA   HB3  H  N N 74  
ALA   HXT  H  N N 75  
ARG   N    N  N N 76  
ARG   CA   C  N S 77  
ARG   C    C  N N 78  
ARG   O    O  N N 79  
ARG   CB   C  N N 80  
ARG   CG   C  N N 81  
ARG   CD   C  N N 82  
ARG   NE   N  N N 83  
ARG   CZ   C  N N 84  
ARG   NH1  N  N N 85  
ARG   NH2  N  N N 86  
ARG   OXT  O  N N 87  
ARG   H    H  N N 88  
ARG   H2   H  N N 89  
ARG   HA   H  N N 90  
ARG   HB2  H  N N 91  
ARG   HB3  H  N N 92  
ARG   HG2  H  N N 93  
ARG   HG3  H  N N 94  
ARG   HD2  H  N N 95  
ARG   HD3  H  N N 96  
ARG   HE   H  N N 97  
ARG   HH11 H  N N 98  
ARG   HH12 H  N N 99  
ARG   HH21 H  N N 100 
ARG   HH22 H  N N 101 
ARG   HXT  H  N N 102 
ASN   N    N  N N 103 
ASN   CA   C  N S 104 
ASN   C    C  N N 105 
ASN   O    O  N N 106 
ASN   CB   C  N N 107 
ASN   CG   C  N N 108 
ASN   OD1  O  N N 109 
ASN   ND2  N  N N 110 
ASN   OXT  O  N N 111 
ASN   H    H  N N 112 
ASN   H2   H  N N 113 
ASN   HA   H  N N 114 
ASN   HB2  H  N N 115 
ASN   HB3  H  N N 116 
ASN   HD21 H  N N 117 
ASN   HD22 H  N N 118 
ASN   HXT  H  N N 119 
ASP   N    N  N N 120 
ASP   CA   C  N S 121 
ASP   C    C  N N 122 
ASP   O    O  N N 123 
ASP   CB   C  N N 124 
ASP   CG   C  N N 125 
ASP   OD1  O  N N 126 
ASP   OD2  O  N N 127 
ASP   OXT  O  N N 128 
ASP   H    H  N N 129 
ASP   H2   H  N N 130 
ASP   HA   H  N N 131 
ASP   HB2  H  N N 132 
ASP   HB3  H  N N 133 
ASP   HD2  H  N N 134 
ASP   HXT  H  N N 135 
CYS   N    N  N N 136 
CYS   CA   C  N R 137 
CYS   C    C  N N 138 
CYS   O    O  N N 139 
CYS   CB   C  N N 140 
CYS   SG   S  N N 141 
CYS   OXT  O  N N 142 
CYS   H    H  N N 143 
CYS   H2   H  N N 144 
CYS   HA   H  N N 145 
CYS   HB2  H  N N 146 
CYS   HB3  H  N N 147 
CYS   HG   H  N N 148 
CYS   HXT  H  N N 149 
GLN   N    N  N N 150 
GLN   CA   C  N S 151 
GLN   C    C  N N 152 
GLN   O    O  N N 153 
GLN   CB   C  N N 154 
GLN   CG   C  N N 155 
GLN   CD   C  N N 156 
GLN   OE1  O  N N 157 
GLN   NE2  N  N N 158 
GLN   OXT  O  N N 159 
GLN   H    H  N N 160 
GLN   H2   H  N N 161 
GLN   HA   H  N N 162 
GLN   HB2  H  N N 163 
GLN   HB3  H  N N 164 
GLN   HG2  H  N N 165 
GLN   HG3  H  N N 166 
GLN   HE21 H  N N 167 
GLN   HE22 H  N N 168 
GLN   HXT  H  N N 169 
GLU   N    N  N N 170 
GLU   CA   C  N S 171 
GLU   C    C  N N 172 
GLU   O    O  N N 173 
GLU   CB   C  N N 174 
GLU   CG   C  N N 175 
GLU   CD   C  N N 176 
GLU   OE1  O  N N 177 
GLU   OE2  O  N N 178 
GLU   OXT  O  N N 179 
GLU   H    H  N N 180 
GLU   H2   H  N N 181 
GLU   HA   H  N N 182 
GLU   HB2  H  N N 183 
GLU   HB3  H  N N 184 
GLU   HG2  H  N N 185 
GLU   HG3  H  N N 186 
GLU   HE2  H  N N 187 
GLU   HXT  H  N N 188 
GLY   N    N  N N 189 
GLY   CA   C  N N 190 
GLY   C    C  N N 191 
GLY   O    O  N N 192 
GLY   OXT  O  N N 193 
GLY   H    H  N N 194 
GLY   H2   H  N N 195 
GLY   HA2  H  N N 196 
GLY   HA3  H  N N 197 
GLY   HXT  H  N N 198 
GOL   C1   C  N N 199 
GOL   O1   O  N N 200 
GOL   C2   C  N N 201 
GOL   O2   O  N N 202 
GOL   C3   C  N N 203 
GOL   O3   O  N N 204 
GOL   H11  H  N N 205 
GOL   H12  H  N N 206 
GOL   HO1  H  N N 207 
GOL   H2   H  N N 208 
GOL   HO2  H  N N 209 
GOL   H31  H  N N 210 
GOL   H32  H  N N 211 
GOL   HO3  H  N N 212 
HIS   N    N  N N 213 
HIS   CA   C  N S 214 
HIS   C    C  N N 215 
HIS   O    O  N N 216 
HIS   CB   C  N N 217 
HIS   CG   C  Y N 218 
HIS   ND1  N  Y N 219 
HIS   CD2  C  Y N 220 
HIS   CE1  C  Y N 221 
HIS   NE2  N  Y N 222 
HIS   OXT  O  N N 223 
HIS   H    H  N N 224 
HIS   H2   H  N N 225 
HIS   HA   H  N N 226 
HIS   HB2  H  N N 227 
HIS   HB3  H  N N 228 
HIS   HD1  H  N N 229 
HIS   HD2  H  N N 230 
HIS   HE1  H  N N 231 
HIS   HE2  H  N N 232 
HIS   HXT  H  N N 233 
HOH   O    O  N N 234 
HOH   H1   H  N N 235 
HOH   H2   H  N N 236 
ILE   N    N  N N 237 
ILE   CA   C  N S 238 
ILE   C    C  N N 239 
ILE   O    O  N N 240 
ILE   CB   C  N S 241 
ILE   CG1  C  N N 242 
ILE   CG2  C  N N 243 
ILE   CD1  C  N N 244 
ILE   OXT  O  N N 245 
ILE   H    H  N N 246 
ILE   H2   H  N N 247 
ILE   HA   H  N N 248 
ILE   HB   H  N N 249 
ILE   HG12 H  N N 250 
ILE   HG13 H  N N 251 
ILE   HG21 H  N N 252 
ILE   HG22 H  N N 253 
ILE   HG23 H  N N 254 
ILE   HD11 H  N N 255 
ILE   HD12 H  N N 256 
ILE   HD13 H  N N 257 
ILE   HXT  H  N N 258 
LEU   N    N  N N 259 
LEU   CA   C  N S 260 
LEU   C    C  N N 261 
LEU   O    O  N N 262 
LEU   CB   C  N N 263 
LEU   CG   C  N N 264 
LEU   CD1  C  N N 265 
LEU   CD2  C  N N 266 
LEU   OXT  O  N N 267 
LEU   H    H  N N 268 
LEU   H2   H  N N 269 
LEU   HA   H  N N 270 
LEU   HB2  H  N N 271 
LEU   HB3  H  N N 272 
LEU   HG   H  N N 273 
LEU   HD11 H  N N 274 
LEU   HD12 H  N N 275 
LEU   HD13 H  N N 276 
LEU   HD21 H  N N 277 
LEU   HD22 H  N N 278 
LEU   HD23 H  N N 279 
LEU   HXT  H  N N 280 
LYS   N    N  N N 281 
LYS   CA   C  N S 282 
LYS   C    C  N N 283 
LYS   O    O  N N 284 
LYS   CB   C  N N 285 
LYS   CG   C  N N 286 
LYS   CD   C  N N 287 
LYS   CE   C  N N 288 
LYS   NZ   N  N N 289 
LYS   OXT  O  N N 290 
LYS   H    H  N N 291 
LYS   H2   H  N N 292 
LYS   HA   H  N N 293 
LYS   HB2  H  N N 294 
LYS   HB3  H  N N 295 
LYS   HG2  H  N N 296 
LYS   HG3  H  N N 297 
LYS   HD2  H  N N 298 
LYS   HD3  H  N N 299 
LYS   HE2  H  N N 300 
LYS   HE3  H  N N 301 
LYS   HZ1  H  N N 302 
LYS   HZ2  H  N N 303 
LYS   HZ3  H  N N 304 
LYS   HXT  H  N N 305 
MET   N    N  N N 306 
MET   CA   C  N S 307 
MET   C    C  N N 308 
MET   O    O  N N 309 
MET   CB   C  N N 310 
MET   CG   C  N N 311 
MET   SD   S  N N 312 
MET   CE   C  N N 313 
MET   OXT  O  N N 314 
MET   H    H  N N 315 
MET   H2   H  N N 316 
MET   HA   H  N N 317 
MET   HB2  H  N N 318 
MET   HB3  H  N N 319 
MET   HG2  H  N N 320 
MET   HG3  H  N N 321 
MET   HE1  H  N N 322 
MET   HE2  H  N N 323 
MET   HE3  H  N N 324 
MET   HXT  H  N N 325 
PHE   N    N  N N 326 
PHE   CA   C  N S 327 
PHE   C    C  N N 328 
PHE   O    O  N N 329 
PHE   CB   C  N N 330 
PHE   CG   C  Y N 331 
PHE   CD1  C  Y N 332 
PHE   CD2  C  Y N 333 
PHE   CE1  C  Y N 334 
PHE   CE2  C  Y N 335 
PHE   CZ   C  Y N 336 
PHE   OXT  O  N N 337 
PHE   H    H  N N 338 
PHE   H2   H  N N 339 
PHE   HA   H  N N 340 
PHE   HB2  H  N N 341 
PHE   HB3  H  N N 342 
PHE   HD1  H  N N 343 
PHE   HD2  H  N N 344 
PHE   HE1  H  N N 345 
PHE   HE2  H  N N 346 
PHE   HZ   H  N N 347 
PHE   HXT  H  N N 348 
PRO   N    N  N N 349 
PRO   CA   C  N S 350 
PRO   C    C  N N 351 
PRO   O    O  N N 352 
PRO   CB   C  N N 353 
PRO   CG   C  N N 354 
PRO   CD   C  N N 355 
PRO   OXT  O  N N 356 
PRO   H    H  N N 357 
PRO   HA   H  N N 358 
PRO   HB2  H  N N 359 
PRO   HB3  H  N N 360 
PRO   HG2  H  N N 361 
PRO   HG3  H  N N 362 
PRO   HD2  H  N N 363 
PRO   HD3  H  N N 364 
PRO   HXT  H  N N 365 
SER   N    N  N N 366 
SER   CA   C  N S 367 
SER   C    C  N N 368 
SER   O    O  N N 369 
SER   CB   C  N N 370 
SER   OG   O  N N 371 
SER   OXT  O  N N 372 
SER   H    H  N N 373 
SER   H2   H  N N 374 
SER   HA   H  N N 375 
SER   HB2  H  N N 376 
SER   HB3  H  N N 377 
SER   HG   H  N N 378 
SER   HXT  H  N N 379 
THR   N    N  N N 380 
THR   CA   C  N S 381 
THR   C    C  N N 382 
THR   O    O  N N 383 
THR   CB   C  N R 384 
THR   OG1  O  N N 385 
THR   CG2  C  N N 386 
THR   OXT  O  N N 387 
THR   H    H  N N 388 
THR   H2   H  N N 389 
THR   HA   H  N N 390 
THR   HB   H  N N 391 
THR   HG1  H  N N 392 
THR   HG21 H  N N 393 
THR   HG22 H  N N 394 
THR   HG23 H  N N 395 
THR   HXT  H  N N 396 
TRP   N    N  N N 397 
TRP   CA   C  N S 398 
TRP   C    C  N N 399 
TRP   O    O  N N 400 
TRP   CB   C  N N 401 
TRP   CG   C  Y N 402 
TRP   CD1  C  Y N 403 
TRP   CD2  C  Y N 404 
TRP   NE1  N  Y N 405 
TRP   CE2  C  Y N 406 
TRP   CE3  C  Y N 407 
TRP   CZ2  C  Y N 408 
TRP   CZ3  C  Y N 409 
TRP   CH2  C  Y N 410 
TRP   OXT  O  N N 411 
TRP   H    H  N N 412 
TRP   H2   H  N N 413 
TRP   HA   H  N N 414 
TRP   HB2  H  N N 415 
TRP   HB3  H  N N 416 
TRP   HD1  H  N N 417 
TRP   HE1  H  N N 418 
TRP   HE3  H  N N 419 
TRP   HZ2  H  N N 420 
TRP   HZ3  H  N N 421 
TRP   HH2  H  N N 422 
TRP   HXT  H  N N 423 
TYR   N    N  N N 424 
TYR   CA   C  N S 425 
TYR   C    C  N N 426 
TYR   O    O  N N 427 
TYR   CB   C  N N 428 
TYR   CG   C  Y N 429 
TYR   CD1  C  Y N 430 
TYR   CD2  C  Y N 431 
TYR   CE1  C  Y N 432 
TYR   CE2  C  Y N 433 
TYR   CZ   C  Y N 434 
TYR   OH   O  N N 435 
TYR   OXT  O  N N 436 
TYR   H    H  N N 437 
TYR   H2   H  N N 438 
TYR   HA   H  N N 439 
TYR   HB2  H  N N 440 
TYR   HB3  H  N N 441 
TYR   HD1  H  N N 442 
TYR   HD2  H  N N 443 
TYR   HE1  H  N N 444 
TYR   HE2  H  N N 445 
TYR   HH   H  N N 446 
TYR   HXT  H  N N 447 
VAL   N    N  N N 448 
VAL   CA   C  N S 449 
VAL   C    C  N N 450 
VAL   O    O  N N 451 
VAL   CB   C  N N 452 
VAL   CG1  C  N N 453 
VAL   CG2  C  N N 454 
VAL   OXT  O  N N 455 
VAL   H    H  N N 456 
VAL   H2   H  N N 457 
VAL   HA   H  N N 458 
VAL   HB   H  N N 459 
VAL   HG11 H  N N 460 
VAL   HG12 H  N N 461 
VAL   HG13 H  N N 462 
VAL   HG21 H  N N 463 
VAL   HG22 H  N N 464 
VAL   HG23 H  N N 465 
VAL   HXT  H  N N 466 
ZN    ZN   ZN N N 467 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
A1LZ8 C09 C08  sing N N 1   
A1LZ8 C09 C10  sing N N 2   
A1LZ8 C32 N31  sing N N 3   
A1LZ8 C08 C07  sing N N 4   
A1LZ8 C08 N12  sing N N 5   
A1LZ8 N31 C29  sing N N 6   
A1LZ8 N31 C22  sing N N 7   
A1LZ8 C10 C11  sing N N 8   
A1LZ8 C10 N12  sing N N 9   
A1LZ8 O30 C29  doub N N 10  
A1LZ8 C07 N06  sing N N 11  
A1LZ8 C29 C28  sing N N 12  
A1LZ8 C11 N06  sing N N 13  
A1LZ8 N06 C05  sing N N 14  
A1LZ8 C22 C21  doub Y N 15  
A1LZ8 C22 C23  sing Y N 16  
A1LZ8 C21 C20  sing Y N 17  
A1LZ8 C05 C04  sing Y N 18  
A1LZ8 C05 C13  doub Y N 19  
A1LZ8 C04 C03  doub Y N 20  
A1LZ8 O01 C02  doub N N 21  
A1LZ8 C13 C14  sing Y N 22  
A1LZ8 C28 C23  sing Y N 23  
A1LZ8 C28 C27  doub Y N 24  
A1LZ8 C23 C24  doub Y N 25  
A1LZ8 C03 C02  sing N N 26  
A1LZ8 C03 C15  sing Y N 27  
A1LZ8 C20 C19  doub Y N 28  
A1LZ8 C14 C15  doub Y N 29  
A1LZ8 C02 N17  sing N N 30  
A1LZ8 C15 C16  sing N N 31  
A1LZ8 C27 C26  sing Y N 32  
A1LZ8 C24 C19  sing Y N 33  
A1LZ8 C24 C25  sing Y N 34  
A1LZ8 C19 C18  sing N N 35  
A1LZ8 C26 C25  doub Y N 36  
A1LZ8 N17 C18  sing N N 37  
A1LZ8 C18 C34  sing N N 38  
A1LZ8 C18 C33  sing N N 39  
A1LZ8 C34 C33  sing N N 40  
A1LZ8 C04 H1   sing N N 41  
A1LZ8 C07 H2   sing N N 42  
A1LZ8 C07 H3   sing N N 43  
A1LZ8 C08 H4   sing N N 44  
A1LZ8 C09 H5   sing N N 45  
A1LZ8 C10 H6   sing N N 46  
A1LZ8 C11 H7   sing N N 47  
A1LZ8 C11 H8   sing N N 48  
A1LZ8 C13 H9   sing N N 49  
A1LZ8 C14 H10  sing N N 50  
A1LZ8 C16 H11  sing N N 51  
A1LZ8 C16 H12  sing N N 52  
A1LZ8 C16 H13  sing N N 53  
A1LZ8 C20 H14  sing N N 54  
A1LZ8 C21 H15  sing N N 55  
A1LZ8 C25 H16  sing N N 56  
A1LZ8 C26 H17  sing N N 57  
A1LZ8 C27 H18  sing N N 58  
A1LZ8 C32 H19  sing N N 59  
A1LZ8 C32 H20  sing N N 60  
A1LZ8 C32 H21  sing N N 61  
A1LZ8 C33 H22  sing N N 62  
A1LZ8 C33 H23  sing N N 63  
A1LZ8 C34 H24  sing N N 64  
A1LZ8 C34 H25  sing N N 65  
A1LZ8 N12 H26  sing N N 66  
A1LZ8 N17 H27  sing N N 67  
A1LZ8 C09 H28  sing N N 68  
ALA   N   CA   sing N N 69  
ALA   N   H    sing N N 70  
ALA   N   H2   sing N N 71  
ALA   CA  C    sing N N 72  
ALA   CA  CB   sing N N 73  
ALA   CA  HA   sing N N 74  
ALA   C   O    doub N N 75  
ALA   C   OXT  sing N N 76  
ALA   CB  HB1  sing N N 77  
ALA   CB  HB2  sing N N 78  
ALA   CB  HB3  sing N N 79  
ALA   OXT HXT  sing N N 80  
ARG   N   CA   sing N N 81  
ARG   N   H    sing N N 82  
ARG   N   H2   sing N N 83  
ARG   CA  C    sing N N 84  
ARG   CA  CB   sing N N 85  
ARG   CA  HA   sing N N 86  
ARG   C   O    doub N N 87  
ARG   C   OXT  sing N N 88  
ARG   CB  CG   sing N N 89  
ARG   CB  HB2  sing N N 90  
ARG   CB  HB3  sing N N 91  
ARG   CG  CD   sing N N 92  
ARG   CG  HG2  sing N N 93  
ARG   CG  HG3  sing N N 94  
ARG   CD  NE   sing N N 95  
ARG   CD  HD2  sing N N 96  
ARG   CD  HD3  sing N N 97  
ARG   NE  CZ   sing N N 98  
ARG   NE  HE   sing N N 99  
ARG   CZ  NH1  sing N N 100 
ARG   CZ  NH2  doub N N 101 
ARG   NH1 HH11 sing N N 102 
ARG   NH1 HH12 sing N N 103 
ARG   NH2 HH21 sing N N 104 
ARG   NH2 HH22 sing N N 105 
ARG   OXT HXT  sing N N 106 
ASN   N   CA   sing N N 107 
ASN   N   H    sing N N 108 
ASN   N   H2   sing N N 109 
ASN   CA  C    sing N N 110 
ASN   CA  CB   sing N N 111 
ASN   CA  HA   sing N N 112 
ASN   C   O    doub N N 113 
ASN   C   OXT  sing N N 114 
ASN   CB  CG   sing N N 115 
ASN   CB  HB2  sing N N 116 
ASN   CB  HB3  sing N N 117 
ASN   CG  OD1  doub N N 118 
ASN   CG  ND2  sing N N 119 
ASN   ND2 HD21 sing N N 120 
ASN   ND2 HD22 sing N N 121 
ASN   OXT HXT  sing N N 122 
ASP   N   CA   sing N N 123 
ASP   N   H    sing N N 124 
ASP   N   H2   sing N N 125 
ASP   CA  C    sing N N 126 
ASP   CA  CB   sing N N 127 
ASP   CA  HA   sing N N 128 
ASP   C   O    doub N N 129 
ASP   C   OXT  sing N N 130 
ASP   CB  CG   sing N N 131 
ASP   CB  HB2  sing N N 132 
ASP   CB  HB3  sing N N 133 
ASP   CG  OD1  doub N N 134 
ASP   CG  OD2  sing N N 135 
ASP   OD2 HD2  sing N N 136 
ASP   OXT HXT  sing N N 137 
CYS   N   CA   sing N N 138 
CYS   N   H    sing N N 139 
CYS   N   H2   sing N N 140 
CYS   CA  C    sing N N 141 
CYS   CA  CB   sing N N 142 
CYS   CA  HA   sing N N 143 
CYS   C   O    doub N N 144 
CYS   C   OXT  sing N N 145 
CYS   CB  SG   sing N N 146 
CYS   CB  HB2  sing N N 147 
CYS   CB  HB3  sing N N 148 
CYS   SG  HG   sing N N 149 
CYS   OXT HXT  sing N N 150 
GLN   N   CA   sing N N 151 
GLN   N   H    sing N N 152 
GLN   N   H2   sing N N 153 
GLN   CA  C    sing N N 154 
GLN   CA  CB   sing N N 155 
GLN   CA  HA   sing N N 156 
GLN   C   O    doub N N 157 
GLN   C   OXT  sing N N 158 
GLN   CB  CG   sing N N 159 
GLN   CB  HB2  sing N N 160 
GLN   CB  HB3  sing N N 161 
GLN   CG  CD   sing N N 162 
GLN   CG  HG2  sing N N 163 
GLN   CG  HG3  sing N N 164 
GLN   CD  OE1  doub N N 165 
GLN   CD  NE2  sing N N 166 
GLN   NE2 HE21 sing N N 167 
GLN   NE2 HE22 sing N N 168 
GLN   OXT HXT  sing N N 169 
GLU   N   CA   sing N N 170 
GLU   N   H    sing N N 171 
GLU   N   H2   sing N N 172 
GLU   CA  C    sing N N 173 
GLU   CA  CB   sing N N 174 
GLU   CA  HA   sing N N 175 
GLU   C   O    doub N N 176 
GLU   C   OXT  sing N N 177 
GLU   CB  CG   sing N N 178 
GLU   CB  HB2  sing N N 179 
GLU   CB  HB3  sing N N 180 
GLU   CG  CD   sing N N 181 
GLU   CG  HG2  sing N N 182 
GLU   CG  HG3  sing N N 183 
GLU   CD  OE1  doub N N 184 
GLU   CD  OE2  sing N N 185 
GLU   OE2 HE2  sing N N 186 
GLU   OXT HXT  sing N N 187 
GLY   N   CA   sing N N 188 
GLY   N   H    sing N N 189 
GLY   N   H2   sing N N 190 
GLY   CA  C    sing N N 191 
GLY   CA  HA2  sing N N 192 
GLY   CA  HA3  sing N N 193 
GLY   C   O    doub N N 194 
GLY   C   OXT  sing N N 195 
GLY   OXT HXT  sing N N 196 
GOL   C1  O1   sing N N 197 
GOL   C1  C2   sing N N 198 
GOL   C1  H11  sing N N 199 
GOL   C1  H12  sing N N 200 
GOL   O1  HO1  sing N N 201 
GOL   C2  O2   sing N N 202 
GOL   C2  C3   sing N N 203 
GOL   C2  H2   sing N N 204 
GOL   O2  HO2  sing N N 205 
GOL   C3  O3   sing N N 206 
GOL   C3  H31  sing N N 207 
GOL   C3  H32  sing N N 208 
GOL   O3  HO3  sing N N 209 
HIS   N   CA   sing N N 210 
HIS   N   H    sing N N 211 
HIS   N   H2   sing N N 212 
HIS   CA  C    sing N N 213 
HIS   CA  CB   sing N N 214 
HIS   CA  HA   sing N N 215 
HIS   C   O    doub N N 216 
HIS   C   OXT  sing N N 217 
HIS   CB  CG   sing N N 218 
HIS   CB  HB2  sing N N 219 
HIS   CB  HB3  sing N N 220 
HIS   CG  ND1  sing Y N 221 
HIS   CG  CD2  doub Y N 222 
HIS   ND1 CE1  doub Y N 223 
HIS   ND1 HD1  sing N N 224 
HIS   CD2 NE2  sing Y N 225 
HIS   CD2 HD2  sing N N 226 
HIS   CE1 NE2  sing Y N 227 
HIS   CE1 HE1  sing N N 228 
HIS   NE2 HE2  sing N N 229 
HIS   OXT HXT  sing N N 230 
HOH   O   H1   sing N N 231 
HOH   O   H2   sing N N 232 
ILE   N   CA   sing N N 233 
ILE   N   H    sing N N 234 
ILE   N   H2   sing N N 235 
ILE   CA  C    sing N N 236 
ILE   CA  CB   sing N N 237 
ILE   CA  HA   sing N N 238 
ILE   C   O    doub N N 239 
ILE   C   OXT  sing N N 240 
ILE   CB  CG1  sing N N 241 
ILE   CB  CG2  sing N N 242 
ILE   CB  HB   sing N N 243 
ILE   CG1 CD1  sing N N 244 
ILE   CG1 HG12 sing N N 245 
ILE   CG1 HG13 sing N N 246 
ILE   CG2 HG21 sing N N 247 
ILE   CG2 HG22 sing N N 248 
ILE   CG2 HG23 sing N N 249 
ILE   CD1 HD11 sing N N 250 
ILE   CD1 HD12 sing N N 251 
ILE   CD1 HD13 sing N N 252 
ILE   OXT HXT  sing N N 253 
LEU   N   CA   sing N N 254 
LEU   N   H    sing N N 255 
LEU   N   H2   sing N N 256 
LEU   CA  C    sing N N 257 
LEU   CA  CB   sing N N 258 
LEU   CA  HA   sing N N 259 
LEU   C   O    doub N N 260 
LEU   C   OXT  sing N N 261 
LEU   CB  CG   sing N N 262 
LEU   CB  HB2  sing N N 263 
LEU   CB  HB3  sing N N 264 
LEU   CG  CD1  sing N N 265 
LEU   CG  CD2  sing N N 266 
LEU   CG  HG   sing N N 267 
LEU   CD1 HD11 sing N N 268 
LEU   CD1 HD12 sing N N 269 
LEU   CD1 HD13 sing N N 270 
LEU   CD2 HD21 sing N N 271 
LEU   CD2 HD22 sing N N 272 
LEU   CD2 HD23 sing N N 273 
LEU   OXT HXT  sing N N 274 
LYS   N   CA   sing N N 275 
LYS   N   H    sing N N 276 
LYS   N   H2   sing N N 277 
LYS   CA  C    sing N N 278 
LYS   CA  CB   sing N N 279 
LYS   CA  HA   sing N N 280 
LYS   C   O    doub N N 281 
LYS   C   OXT  sing N N 282 
LYS   CB  CG   sing N N 283 
LYS   CB  HB2  sing N N 284 
LYS   CB  HB3  sing N N 285 
LYS   CG  CD   sing N N 286 
LYS   CG  HG2  sing N N 287 
LYS   CG  HG3  sing N N 288 
LYS   CD  CE   sing N N 289 
LYS   CD  HD2  sing N N 290 
LYS   CD  HD3  sing N N 291 
LYS   CE  NZ   sing N N 292 
LYS   CE  HE2  sing N N 293 
LYS   CE  HE3  sing N N 294 
LYS   NZ  HZ1  sing N N 295 
LYS   NZ  HZ2  sing N N 296 
LYS   NZ  HZ3  sing N N 297 
LYS   OXT HXT  sing N N 298 
MET   N   CA   sing N N 299 
MET   N   H    sing N N 300 
MET   N   H2   sing N N 301 
MET   CA  C    sing N N 302 
MET   CA  CB   sing N N 303 
MET   CA  HA   sing N N 304 
MET   C   O    doub N N 305 
MET   C   OXT  sing N N 306 
MET   CB  CG   sing N N 307 
MET   CB  HB2  sing N N 308 
MET   CB  HB3  sing N N 309 
MET   CG  SD   sing N N 310 
MET   CG  HG2  sing N N 311 
MET   CG  HG3  sing N N 312 
MET   SD  CE   sing N N 313 
MET   CE  HE1  sing N N 314 
MET   CE  HE2  sing N N 315 
MET   CE  HE3  sing N N 316 
MET   OXT HXT  sing N N 317 
PHE   N   CA   sing N N 318 
PHE   N   H    sing N N 319 
PHE   N   H2   sing N N 320 
PHE   CA  C    sing N N 321 
PHE   CA  CB   sing N N 322 
PHE   CA  HA   sing N N 323 
PHE   C   O    doub N N 324 
PHE   C   OXT  sing N N 325 
PHE   CB  CG   sing N N 326 
PHE   CB  HB2  sing N N 327 
PHE   CB  HB3  sing N N 328 
PHE   CG  CD1  doub Y N 329 
PHE   CG  CD2  sing Y N 330 
PHE   CD1 CE1  sing Y N 331 
PHE   CD1 HD1  sing N N 332 
PHE   CD2 CE2  doub Y N 333 
PHE   CD2 HD2  sing N N 334 
PHE   CE1 CZ   doub Y N 335 
PHE   CE1 HE1  sing N N 336 
PHE   CE2 CZ   sing Y N 337 
PHE   CE2 HE2  sing N N 338 
PHE   CZ  HZ   sing N N 339 
PHE   OXT HXT  sing N N 340 
PRO   N   CA   sing N N 341 
PRO   N   CD   sing N N 342 
PRO   N   H    sing N N 343 
PRO   CA  C    sing N N 344 
PRO   CA  CB   sing N N 345 
PRO   CA  HA   sing N N 346 
PRO   C   O    doub N N 347 
PRO   C   OXT  sing N N 348 
PRO   CB  CG   sing N N 349 
PRO   CB  HB2  sing N N 350 
PRO   CB  HB3  sing N N 351 
PRO   CG  CD   sing N N 352 
PRO   CG  HG2  sing N N 353 
PRO   CG  HG3  sing N N 354 
PRO   CD  HD2  sing N N 355 
PRO   CD  HD3  sing N N 356 
PRO   OXT HXT  sing N N 357 
SER   N   CA   sing N N 358 
SER   N   H    sing N N 359 
SER   N   H2   sing N N 360 
SER   CA  C    sing N N 361 
SER   CA  CB   sing N N 362 
SER   CA  HA   sing N N 363 
SER   C   O    doub N N 364 
SER   C   OXT  sing N N 365 
SER   CB  OG   sing N N 366 
SER   CB  HB2  sing N N 367 
SER   CB  HB3  sing N N 368 
SER   OG  HG   sing N N 369 
SER   OXT HXT  sing N N 370 
THR   N   CA   sing N N 371 
THR   N   H    sing N N 372 
THR   N   H2   sing N N 373 
THR   CA  C    sing N N 374 
THR   CA  CB   sing N N 375 
THR   CA  HA   sing N N 376 
THR   C   O    doub N N 377 
THR   C   OXT  sing N N 378 
THR   CB  OG1  sing N N 379 
THR   CB  CG2  sing N N 380 
THR   CB  HB   sing N N 381 
THR   OG1 HG1  sing N N 382 
THR   CG2 HG21 sing N N 383 
THR   CG2 HG22 sing N N 384 
THR   CG2 HG23 sing N N 385 
THR   OXT HXT  sing N N 386 
TRP   N   CA   sing N N 387 
TRP   N   H    sing N N 388 
TRP   N   H2   sing N N 389 
TRP   CA  C    sing N N 390 
TRP   CA  CB   sing N N 391 
TRP   CA  HA   sing N N 392 
TRP   C   O    doub N N 393 
TRP   C   OXT  sing N N 394 
TRP   CB  CG   sing N N 395 
TRP   CB  HB2  sing N N 396 
TRP   CB  HB3  sing N N 397 
TRP   CG  CD1  doub Y N 398 
TRP   CG  CD2  sing Y N 399 
TRP   CD1 NE1  sing Y N 400 
TRP   CD1 HD1  sing N N 401 
TRP   CD2 CE2  doub Y N 402 
TRP   CD2 CE3  sing Y N 403 
TRP   NE1 CE2  sing Y N 404 
TRP   NE1 HE1  sing N N 405 
TRP   CE2 CZ2  sing Y N 406 
TRP   CE3 CZ3  doub Y N 407 
TRP   CE3 HE3  sing N N 408 
TRP   CZ2 CH2  doub Y N 409 
TRP   CZ2 HZ2  sing N N 410 
TRP   CZ3 CH2  sing Y N 411 
TRP   CZ3 HZ3  sing N N 412 
TRP   CH2 HH2  sing N N 413 
TRP   OXT HXT  sing N N 414 
TYR   N   CA   sing N N 415 
TYR   N   H    sing N N 416 
TYR   N   H2   sing N N 417 
TYR   CA  C    sing N N 418 
TYR   CA  CB   sing N N 419 
TYR   CA  HA   sing N N 420 
TYR   C   O    doub N N 421 
TYR   C   OXT  sing N N 422 
TYR   CB  CG   sing N N 423 
TYR   CB  HB2  sing N N 424 
TYR   CB  HB3  sing N N 425 
TYR   CG  CD1  doub Y N 426 
TYR   CG  CD2  sing Y N 427 
TYR   CD1 CE1  sing Y N 428 
TYR   CD1 HD1  sing N N 429 
TYR   CD2 CE2  doub Y N 430 
TYR   CD2 HD2  sing N N 431 
TYR   CE1 CZ   doub Y N 432 
TYR   CE1 HE1  sing N N 433 
TYR   CE2 CZ   sing Y N 434 
TYR   CE2 HE2  sing N N 435 
TYR   CZ  OH   sing N N 436 
TYR   OH  HH   sing N N 437 
TYR   OXT HXT  sing N N 438 
VAL   N   CA   sing N N 439 
VAL   N   H    sing N N 440 
VAL   N   H2   sing N N 441 
VAL   CA  C    sing N N 442 
VAL   CA  CB   sing N N 443 
VAL   CA  HA   sing N N 444 
VAL   C   O    doub N N 445 
VAL   C   OXT  sing N N 446 
VAL   CB  CG1  sing N N 447 
VAL   CB  CG2  sing N N 448 
VAL   CB  HB   sing N N 449 
VAL   CG1 HG11 sing N N 450 
VAL   CG1 HG12 sing N N 451 
VAL   CG1 HG13 sing N N 452 
VAL   CG2 HG21 sing N N 453 
VAL   CG2 HG22 sing N N 454 
VAL   CG2 HG23 sing N N 455 
VAL   OXT HXT  sing N N 456 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'Ministry of Science and Technology (MoST, China)'    China GZNL2023401008 1 
'Ministry of Science and Technology (MoST, China)'    China SRPG22-002     2 
'Ministry of Science and Technology (MoST, China)'    China SRPG22-003     3 
'National Natural Science Foundation of China (NSFC)' China 82170473       4 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   7CJM 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    8YX5 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.021336 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.003471 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.006898 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.016858 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C  
H  
N  
O  
S  
ZN 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1     N  N    . GLY   A 1 1   ? 29.178  -35.532 -8.680  1.00 24.80 ? 0   GLY   A N    1 
ATOM   2     C  CA   . GLY   A 1 1   ? 30.267  -35.434 -7.730  1.00 23.36 ? 0   GLY   A CA   1 
ATOM   3     C  C    . GLY   A 1 1   ? 29.811  -35.275 -6.284  1.00 22.69 ? 0   GLY   A C    1 
ATOM   4     O  O    . GLY   A 1 1   ? 28.620  -35.363 -5.969  1.00 23.09 ? 0   GLY   A O    1 
ATOM   5     N  N    . GLU   A 1 2   ? 30.766  -35.027 -5.399  1.00 23.03 ? 1   GLU   A N    1 
ATOM   6     C  CA   . GLU   A 1 2   ? 30.453  -34.953 -3.975  1.00 27.30 ? 1   GLU   A CA   1 
ATOM   7     C  C    . GLU   A 1 2   ? 29.434  -33.852 -3.695  1.00 25.72 ? 1   GLU   A C    1 
ATOM   8     O  O    . GLU   A 1 2   ? 29.444  -32.796 -4.327  1.00 28.12 ? 1   GLU   A O    1 
ATOM   9     C  CB   . GLU   A 1 2   ? 31.725  -34.720 -3.170  1.00 34.36 ? 1   GLU   A CB   1 
ATOM   10    C  CG   . GLU   A 1 2   ? 32.231  -33.306 -3.275  1.00 38.13 ? 1   GLU   A CG   1 
ATOM   11    C  CD   . GLU   A 1 2   ? 33.512  -33.101 -2.469  1.00 49.57 ? 1   GLU   A CD   1 
ATOM   12    O  OE1  . GLU   A 1 2   ? 33.708  -33.829 -1.463  1.00 48.66 ? 1   GLU   A OE1  1 
ATOM   13    O  OE2  . GLU   A 1 2   ? 34.297  -32.203 -2.834  1.00 58.43 ? 1   GLU   A OE2  1 
ATOM   14    N  N    . VAL   A 1 3   ? 28.537  -34.108 -2.744  1.00 23.65 ? 2   VAL   A N    1 
ATOM   15    C  CA   . VAL   A 1 3   ? 27.556  -33.119 -2.295  1.00 24.01 ? 2   VAL   A CA   1 
ATOM   16    C  C    . VAL   A 1 3   ? 27.957  -32.700 -0.893  1.00 30.06 ? 2   VAL   A C    1 
ATOM   17    O  O    . VAL   A 1 3   ? 27.786  -33.469 0.069   1.00 27.68 ? 2   VAL   A O    1 
ATOM   18    C  CB   . VAL   A 1 3   ? 26.126  -33.663 -2.309  1.00 23.65 ? 2   VAL   A CB   1 
ATOM   19    C  CG1  . VAL   A 1 3   ? 25.137  -32.650 -1.638  1.00 23.91 ? 2   VAL   A CG1  1 
ATOM   20    C  CG2  . VAL   A 1 3   ? 25.690  -33.983 -3.708  1.00 27.19 ? 2   VAL   A CG2  1 
ATOM   21    N  N    . ARG   A 1 4   ? 28.489  -31.510 -0.770  1.00 25.78 ? 3   ARG   A N    1 
ATOM   22    C  CA   . ARG   A 1 4   ? 28.890  -30.976 0.517   1.00 28.85 ? 3   ARG   A CA   1 
ATOM   23    C  C    . ARG   A 1 4   ? 27.881  -29.942 0.993   1.00 26.51 ? 3   ARG   A C    1 
ATOM   24    O  O    . ARG   A 1 4   ? 27.225  -29.365 0.195   1.00 28.55 ? 3   ARG   A O    1 
ATOM   25    C  CB   . ARG   A 1 4   ? 30.271  -30.341 0.444   1.00 37.37 ? 3   ARG   A CB   1 
ATOM   26    C  CG   . ARG   A 1 4   ? 31.415  -31.310 0.185   1.00 41.03 ? 3   ARG   A CG   1 
ATOM   27    C  CD   . ARG   A 1 4   ? 32.742  -30.572 0.148   1.00 53.72 ? 3   ARG   A CD   1 
ATOM   28    N  NE   . ARG   A 1 4   ? 32.942  -29.820 1.375   1.00 59.72 ? 3   ARG   A NE   1 
ATOM   29    C  CZ   . ARG   A 1 4   ? 33.358  -28.550 1.476   1.00 58.30 ? 3   ARG   A CZ   1 
ATOM   30    N  NH1  . ARG   A 1 4   ? 33.654  -27.810 0.416   1.00 51.78 ? 3   ARG   A NH1  1 
ATOM   31    N  NH2  . ARG   A 1 4   ? 33.466  -28.021 2.674   1.00 53.09 ? 3   ARG   A NH2  1 
ATOM   32    N  N    . THR   A 1 5   ? 27.748  -29.753 2.303   1.00 33.05 ? 4   THR   A N    1 
ATOM   33    C  CA   . THR   A 1 5   ? 26.792  -28.800 2.855   1.00 29.40 ? 4   THR   A CA   1 
ATOM   34    C  C    . THR   A 1 5   ? 27.468  -27.957 3.926   1.00 34.53 ? 4   THR   A C    1 
ATOM   35    O  O    . THR   A 1 5   ? 28.477  -28.350 4.507   1.00 31.95 ? 4   THR   A O    1 
ATOM   36    C  CB   . THR   A 1 5   ? 25.559  -29.475 3.445   1.00 31.63 ? 4   THR   A CB   1 
ATOM   37    O  OG1  . THR   A 1 5   ? 25.912  -30.158 4.655   1.00 40.25 ? 4   THR   A OG1  1 
ATOM   38    C  CG2  . THR   A 1 5   ? 24.895  -30.441 2.458   1.00 34.73 ? 4   THR   A CG2  1 
ATOM   39    N  N    . ILE   A 1 6   ? 26.933  -26.752 4.115   1.00 30.70 ? 5   ILE   A N    1 
ATOM   40    C  CA   . ILE   A 1 6   ? 27.264  -25.885 5.241   1.00 28.35 ? 5   ILE   A CA   1 
ATOM   41    C  C    . ILE   A 1 6   ? 25.961  -25.378 5.844   1.00 28.56 ? 5   ILE   A C    1 
ATOM   42    O  O    . ILE   A 1 6   ? 24.915  -25.366 5.192   1.00 29.36 ? 5   ILE   A O    1 
ATOM   43    C  CB   . ILE   A 1 6   ? 28.178  -24.710 4.832   1.00 29.40 ? 5   ILE   A CB   1 
ATOM   44    C  CG1  . ILE   A 1 6   ? 27.530  -23.845 3.746   1.00 31.80 ? 5   ILE   A CG1  1 
ATOM   45    C  CG2  . ILE   A 1 6   ? 29.565  -25.190 4.396   1.00 38.42 ? 5   ILE   A CG2  1 
ATOM   46    C  CD1  . ILE   A 1 6   ? 28.167  -22.430 3.603   1.00 29.82 ? 5   ILE   A CD1  1 
ATOM   47    N  N    . LYS   A 1 7   ? 26.038  -24.927 7.098   1.00 28.65 ? 6   LYS   A N    1 
ATOM   48    C  CA   . LYS   A 1 7   ? 24.906  -24.296 7.767   1.00 27.90 ? 6   LYS   A CA   1 
ATOM   49    C  C    . LYS   A 1 7   ? 25.061  -22.781 7.661   1.00 25.10 ? 6   LYS   A C    1 
ATOM   50    O  O    . LYS   A 1 7   ? 26.156  -22.260 7.875   1.00 25.38 ? 6   LYS   A O    1 
ATOM   51    C  CB   . LYS   A 1 7   ? 24.837  -24.736 9.227   1.00 31.89 ? 6   LYS   A CB   1 
ATOM   52    C  CG   . LYS   A 1 7   ? 23.971  -23.845 10.109  1.00 43.13 ? 6   LYS   A CG   1 
ATOM   53    C  CD   . LYS   A 1 7   ? 23.851  -24.426 11.512  1.00 44.50 ? 6   LYS   A CD   1 
ATOM   54    C  CE   . LYS   A 1 7   ? 24.618  -23.598 12.538  1.00 43.40 ? 6   LYS   A CE   1 
ATOM   55    N  NZ   . LYS   A 1 7   ? 23.866  -23.572 13.827  1.00 53.61 ? 6   LYS   A NZ   1 
ATOM   56    N  N    . VAL   A 1 8   ? 23.989  -22.093 7.268   1.00 24.13 ? 7   VAL   A N    1 
ATOM   57    C  CA   . VAL   A 1 8   ? 23.938  -20.635 7.254   1.00 24.82 ? 7   VAL   A CA   1 
ATOM   58    C  C    . VAL   A 1 8   ? 22.602  -20.211 7.860   1.00 26.50 ? 7   VAL   A C    1 
ATOM   59    O  O    . VAL   A 1 8   ? 21.732  -21.040 8.142   1.00 25.49 ? 7   VAL   A O    1 
ATOM   60    C  CB   . VAL   A 1 8   ? 24.090  -20.035 5.843   1.00 24.63 ? 7   VAL   A CB   1 
ATOM   61    C  CG1  . VAL   A 1 8   ? 25.332  -20.548 5.143   1.00 24.28 ? 7   VAL   A CG1  1 
ATOM   62    C  CG2  . VAL   A 1 8   ? 22.836  -20.322 5.019   1.00 26.96 ? 7   VAL   A CG2  1 
ATOM   63    H  H    . VAL   A 1 8   ? 23.260  -22.461 6.997   1.00 28.95 ? 7   VAL   A H    1 
ATOM   64    H  HA   . VAL   A 1 8   ? 24.663  -20.292 7.799   1.00 29.79 ? 7   VAL   A HA   1 
ATOM   65    H  HB   . VAL   A 1 8   ? 24.195  -19.075 5.927   1.00 29.55 ? 7   VAL   A HB   1 
ATOM   66    H  HG11 . VAL   A 1 8   ? 25.501  -20.002 4.359   1.00 29.14 ? 7   VAL   A HG11 1 
ATOM   67    H  HG12 . VAL   A 1 8   ? 26.084  -20.492 5.753   1.00 29.14 ? 7   VAL   A HG12 1 
ATOM   68    H  HG13 . VAL   A 1 8   ? 25.188  -21.470 4.878   1.00 29.14 ? 7   VAL   A HG13 1 
ATOM   69    H  HG21 . VAL   A 1 8   ? 23.057  -20.261 4.076   1.00 32.35 ? 7   VAL   A HG21 1 
ATOM   70    H  HG22 . VAL   A 1 8   ? 22.518  -21.214 5.227   1.00 32.35 ? 7   VAL   A HG22 1 
ATOM   71    H  HG23 . VAL   A 1 8   ? 22.155  -19.668 5.242   1.00 32.35 ? 7   VAL   A HG23 1 
ATOM   72    N  N    . PHE   A 1 9   ? 22.433  -18.894 8.046   1.00 23.36 ? 8   PHE   A N    1 
ATOM   73    C  CA   . PHE   A 1 9   ? 21.161  -18.336 8.497   1.00 19.30 ? 8   PHE   A CA   1 
ATOM   74    C  C    . PHE   A 1 9   ? 20.582  -17.458 7.403   1.00 21.60 ? 8   PHE   A C    1 
ATOM   75    O  O    . PHE   A 1 9   ? 21.322  -16.743 6.722   1.00 24.48 ? 8   PHE   A O    1 
ATOM   76    C  CB   . PHE   A 1 9   ? 21.334  -17.500 9.772   1.00 21.38 ? 8   PHE   A CB   1 
ATOM   77    C  CG   . PHE   A 1 9   ? 21.906  -18.261 10.911  1.00 22.88 ? 8   PHE   A CG   1 
ATOM   78    C  CD1  . PHE   A 1 9   ? 21.098  -19.038 11.706  1.00 24.31 ? 8   PHE   A CD1  1 
ATOM   79    C  CD2  . PHE   A 1 9   ? 23.257  -18.198 11.189  1.00 21.78 ? 8   PHE   A CD2  1 
ATOM   80    C  CE1  . PHE   A 1 9   ? 21.634  -19.733 12.775  1.00 23.76 ? 8   PHE   A CE1  1 
ATOM   81    C  CE2  . PHE   A 1 9   ? 23.794  -18.889 12.255  1.00 31.47 ? 8   PHE   A CE2  1 
ATOM   82    C  CZ   . PHE   A 1 9   ? 22.980  -19.663 13.039  1.00 25.96 ? 8   PHE   A CZ   1 
ATOM   83    H  H    . PHE   A 1 9   ? 23.047  -18.306 7.916   1.00 28.03 ? 8   PHE   A H    1 
ATOM   84    H  HA   . PHE   A 1 9   ? 20.544  -19.061 8.686   1.00 23.16 ? 8   PHE   A HA   1 
ATOM   85    H  HB2  . PHE   A 1 9   ? 21.931  -16.759 9.581   1.00 25.66 ? 8   PHE   A HB2  1 
ATOM   86    H  HB3  . PHE   A 1 9   ? 20.466  -17.164 10.045  1.00 25.66 ? 8   PHE   A HB3  1 
ATOM   87    H  HD1  . PHE   A 1 9   ? 20.187  -19.096 11.525  1.00 29.17 ? 8   PHE   A HD1  1 
ATOM   88    H  HD2  . PHE   A 1 9   ? 23.812  -17.683 10.649  1.00 26.13 ? 8   PHE   A HD2  1 
ATOM   89    H  HE1  . PHE   A 1 9   ? 21.081  -20.250 13.316  1.00 28.51 ? 8   PHE   A HE1  1 
ATOM   90    H  HE2  . PHE   A 1 9   ? 24.703  -18.829 12.441  1.00 37.76 ? 8   PHE   A HE2  1 
ATOM   91    H  HZ   . PHE   A 1 9   ? 23.340  -20.141 13.750  1.00 31.15 ? 8   PHE   A HZ   1 
ATOM   92    N  N    . THR   A 1 10  ? 19.271  -17.544 7.199   1.00 19.87 ? 9   THR   A N    1 
ATOM   93    C  CA   . THR   A 1 10  ? 18.593  -16.581 6.348   1.00 19.96 ? 9   THR   A CA   1 
ATOM   94    C  C    . THR   A 1 10  ? 17.717  -15.678 7.203   1.00 21.39 ? 9   THR   A C    1 
ATOM   95    O  O    . THR   A 1 10  ? 17.298  -16.031 8.316   1.00 21.44 ? 9   THR   A O    1 
ATOM   96    C  CB   . THR   A 1 10  ? 17.746  -17.232 5.244   1.00 21.40 ? 9   THR   A CB   1 
ATOM   97    O  OG1  . THR   A 1 10  ? 16.866  -18.197 5.793   1.00 25.57 ? 9   THR   A OG1  1 
ATOM   98    C  CG2  . THR   A 1 10  ? 18.682  -17.908 4.234   1.00 24.19 ? 9   THR   A CG2  1 
ATOM   99    H  H    . THR   A 1 10  ? 18.762  -18.146 7.541   1.00 23.85 ? 9   THR   A H    1 
ATOM   100   H  HA   . THR   A 1 10  ? 19.268  -16.050 5.896   1.00 23.96 ? 9   THR   A HA   1 
ATOM   101   H  HB   . THR   A 1 10  ? 17.212  -16.557 4.796   1.00 25.68 ? 9   THR   A HB   1 
ATOM   102   H  HG1  . THR   A 1 10  ? 16.361  -18.500 5.194   1.00 30.68 ? 9   THR   A HG1  1 
ATOM   103   H  HG21 . THR   A 1 10  ? 18.165  -18.437 3.606   1.00 29.02 ? 9   THR   A HG21 1 
ATOM   104   H  HG22 . THR   A 1 10  ? 19.182  -17.237 3.744   1.00 29.02 ? 9   THR   A HG22 1 
ATOM   105   H  HG23 . THR   A 1 10  ? 19.305  -18.489 4.697   1.00 29.02 ? 9   THR   A HG23 1 
ATOM   106   N  N    . THR   A 1 11  ? 17.427  -14.498 6.652   1.00 22.29 ? 10  THR   A N    1 
ATOM   107   C  CA   . THR   A 1 11  ? 16.680  -13.490 7.379   1.00 22.84 ? 10  THR   A CA   1 
ATOM   108   C  C    . THR   A 1 11  ? 16.127  -12.487 6.381   1.00 23.89 ? 10  THR   A C    1 
ATOM   109   O  O    . THR   A 1 11  ? 16.644  -12.341 5.277   1.00 21.15 ? 10  THR   A O    1 
ATOM   110   C  CB   . THR   A 1 11  ? 17.569  -12.784 8.415   1.00 21.99 ? 10  THR   A CB   1 
ATOM   111   O  OG1  . THR   A 1 11  ? 16.740  -12.038 9.301   1.00 22.49 ? 10  THR   A OG1  1 
ATOM   112   C  CG2  . THR   A 1 11  ? 18.560  -11.826 7.741   1.00 22.28 ? 10  THR   A CG2  1 
ATOM   113   H  H    . THR   A 1 11  ? 17.654  -14.263 5.857   1.00 26.74 ? 10  THR   A H    1 
ATOM   114   H  HA   . THR   A 1 11  ? 15.935  -13.904 7.842   1.00 27.41 ? 10  THR   A HA   1 
ATOM   115   H  HB   . THR   A 1 11  ? 18.080  -13.448 8.902   1.00 26.39 ? 10  THR   A HB   1 
ATOM   116   H  HG1  . THR   A 1 11  ? 16.970  -12.180 10.097  1.00 26.98 ? 10  THR   A HG1  1 
ATOM   117   H  HG21 . THR   A 1 11  ? 19.308  -11.652 8.333   1.00 26.73 ? 10  THR   A HG21 1 
ATOM   118   H  HG22 . THR   A 1 11  ? 18.894  -12.218 6.919   1.00 26.73 ? 10  THR   A HG22 1 
ATOM   119   H  HG23 . THR   A 1 11  ? 18.121  -10.986 7.534   1.00 26.73 ? 10  THR   A HG23 1 
ATOM   120   N  N    . VAL   A 1 12  ? 15.066  -11.803 6.790   1.00 25.32 ? 11  VAL   A N    1 
ATOM   121   C  CA   . VAL   A 1 12  ? 14.635  -10.589 6.116   1.00 22.32 ? 11  VAL   A CA   1 
ATOM   122   C  C    . VAL   A 1 12  ? 14.859  -9.346  6.984   1.00 25.39 ? 11  VAL   A C    1 
ATOM   123   O  O    . VAL   A 1 12  ? 14.799  -8.224  6.454   1.00 24.86 ? 11  VAL   A O    1 
ATOM   124   C  CB   . VAL   A 1 12  ? 13.153  -10.675 5.694   1.00 21.99 ? 11  VAL   A CB   1 
ATOM   125   C  CG1  . VAL   A 1 12  ? 12.964  -11.715 4.593   1.00 30.43 ? 11  VAL   A CG1  1 
ATOM   126   C  CG2  . VAL   A 1 12  ? 12.265  -10.937 6.883   1.00 26.63 ? 11  VAL   A CG2  1 
ATOM   127   H  H    . VAL   A 1 12  ? 14.576  -12.024 7.462   1.00 30.39 ? 11  VAL   A H    1 
ATOM   128   H  HA   . VAL   A 1 12  ? 15.158  -10.483 5.306   1.00 26.79 ? 11  VAL   A HA   1 
ATOM   129   H  HB   . VAL   A 1 12  ? 12.881  -9.820  5.326   1.00 26.39 ? 11  VAL   A HB   1 
ATOM   130   H  HG11 . VAL   A 1 12  ? 12.320  -12.376 4.890   1.00 36.51 ? 11  VAL   A HG11 1 
ATOM   131   H  HG12 . VAL   A 1 12  ? 12.638  -11.272 3.793   1.00 36.51 ? 11  VAL   A HG12 1 
ATOM   132   H  HG13 . VAL   A 1 12  ? 13.816  -12.141 4.411   1.00 36.51 ? 11  VAL   A HG13 1 
ATOM   133   H  HG21 . VAL   A 1 12  ? 11.407  -10.509 6.737   1.00 31.96 ? 11  VAL   A HG21 1 
ATOM   134   H  HG22 . VAL   A 1 12  ? 12.145  -11.894 6.983   1.00 31.96 ? 11  VAL   A HG22 1 
ATOM   135   H  HG23 . VAL   A 1 12  ? 12.686  -10.571 7.677   1.00 31.96 ? 11  VAL   A HG23 1 
ATOM   136   N  N    . ASP   A 1 13  ? 15.069  -9.501  8.289   1.00 24.60 ? 12  ASP   A N    1 
ATOM   137   C  CA   . ASP   A 1 13  ? 15.194  -8.351  9.196   1.00 24.13 ? 12  ASP   A CA   1 
ATOM   138   C  C    . ASP   A 1 13  ? 16.462  -8.315  10.033  1.00 26.52 ? 12  ASP   A C    1 
ATOM   139   O  O    . ASP   A 1 13  ? 16.667  -7.340  10.765  1.00 29.91 ? 12  ASP   A O    1 
ATOM   140   C  CB   . ASP   A 1 13  ? 13.995  -8.294  10.147  1.00 25.98 ? 12  ASP   A CB   1 
ATOM   141   C  CG   . ASP   A 1 13  ? 13.753  -9.613  10.885  1.00 27.65 ? 12  ASP   A CG   1 
ATOM   142   O  OD1  . ASP   A 1 13  ? 14.714  -10.407 11.038  1.00 23.70 ? 12  ASP   A OD1  1 
ATOM   143   O  OD2  . ASP   A 1 13  ? 12.597  -9.832  11.325  1.00 27.42 ? 12  ASP   A OD2  1 
ATOM   144   H  H    . ASP   A 1 13  ? 15.143  -10.263 8.680   1.00 29.52 ? 12  ASP   A H    1 
ATOM   145   H  HA   . ASP   A 1 13  ? 15.197  -7.552  8.647   1.00 28.95 ? 12  ASP   A HA   1 
ATOM   146   H  HB2  . ASP   A 1 13  ? 14.153  -7.604  10.811  1.00 31.18 ? 12  ASP   A HB2  1 
ATOM   147   H  HB3  . ASP   A 1 13  ? 13.197  -8.086  9.636   1.00 31.18 ? 12  ASP   A HB3  1 
ATOM   148   N  N    . ASN   A 1 14  ? 17.300  -9.347  9.981   1.00 25.25 ? 13  ASN   A N    1 
ATOM   149   C  CA   . ASN   A 1 14  ? 18.477  -9.514  10.815  1.00 20.14 ? 13  ASN   A CA   1 
ATOM   150   C  C    . ASN   A 1 14  ? 18.142  -9.525  12.311  1.00 21.45 ? 13  ASN   A C    1 
ATOM   151   O  O    . ASN   A 1 14  ? 19.024  -9.323  13.146  1.00 27.66 ? 13  ASN   A O    1 
ATOM   152   C  CB   . ASN   A 1 14  ? 19.550  -8.469  10.491  1.00 27.49 ? 13  ASN   A CB   1 
ATOM   153   C  CG   . ASN   A 1 14  ? 20.934  -8.929  10.911  1.00 38.20 ? 13  ASN   A CG   1 
ATOM   154   O  OD1  . ASN   A 1 14  ? 21.229  -10.124 10.880  1.00 36.36 ? 13  ASN   A OD1  1 
ATOM   155   N  ND2  . ASN   A 1 14  ? 21.812  -7.987  11.205  1.00 38.94 ? 13  ASN   A ND2  1 
ATOM   156   H  H    . ASN   A 1 14  ? 17.197  -10.003 9.435   1.00 30.30 ? 13  ASN   A H    1 
ATOM   157   H  HA   . ASN   A 1 14  ? 18.862  -10.382 10.619  1.00 24.17 ? 13  ASN   A HA   1 
ATOM   158   H  HB2  . ASN   A 1 14  ? 19.561  -8.309  9.534   1.00 32.99 ? 13  ASN   A HB2  1 
ATOM   159   H  HB3  . ASN   A 1 14  ? 19.348  -7.646  10.962  1.00 32.99 ? 13  ASN   A HB3  1 
ATOM   160   H  HD21 . ASN   A 1 14  ? 21.588  -7.159  11.154  1.00 46.72 ? 13  ASN   A HD21 1 
ATOM   161   H  HD22 . ASN   A 1 14  ? 22.609  -8.203  11.448  1.00 46.72 ? 13  ASN   A HD22 1 
ATOM   162   N  N    . ILE   A 1 15  ? 16.887  -9.792  12.635  1.00 23.23 ? 14  ILE   A N    1 
ATOM   163   C  CA   . ILE   A 1 15  ? 16.444  -10.026 14.001  1.00 28.03 ? 14  ILE   A CA   1 
ATOM   164   C  C    . ILE   A 1 15  ? 16.023  -11.478 14.209  1.00 27.65 ? 14  ILE   A C    1 
ATOM   165   O  O    . ILE   A 1 15  ? 16.337  -12.089 15.229  1.00 27.85 ? 14  ILE   A O    1 
ATOM   166   C  CB   . ILE   A 1 15  ? 15.288  -9.073  14.379  1.00 25.10 ? 14  ILE   A CB   1 
ATOM   167   C  CG1  . ILE   A 1 15  ? 15.716  -7.606  14.268  1.00 32.41 ? 14  ILE   A CG1  1 
ATOM   168   C  CG2  . ILE   A 1 15  ? 14.798  -9.414  15.760  1.00 33.38 ? 14  ILE   A CG2  1 
ATOM   169   C  CD1  . ILE   A 1 15  ? 16.995  -7.320  14.955  1.00 33.18 ? 14  ILE   A CD1  1 
ATOM   170   H  H    . ILE   A 1 15  ? 16.249  -9.846  12.060  1.00 27.88 ? 14  ILE   A H    1 
ATOM   171   H  HA   . ILE   A 1 15  ? 17.191  -9.844  14.593  1.00 33.64 ? 14  ILE   A HA   1 
ATOM   172   H  HB   . ILE   A 1 15  ? 14.558  -9.194  13.751  1.00 30.12 ? 14  ILE   A HB   1 
ATOM   173   H  HG12 . ILE   A 1 15  ? 15.823  -7.380  13.330  1.00 38.90 ? 14  ILE   A HG12 1 
ATOM   174   H  HG13 . ILE   A 1 15  ? 15.031  -7.047  14.667  1.00 38.90 ? 14  ILE   A HG13 1 
ATOM   175   H  HG21 . ILE   A 1 15  ? 14.407  -8.622  16.161  1.00 40.05 ? 14  ILE   A HG21 1 
ATOM   176   H  HG22 . ILE   A 1 15  ? 14.131  -10.116 15.695  1.00 40.05 ? 14  ILE   A HG22 1 
ATOM   177   H  HG23 . ILE   A 1 15  ? 15.547  -9.720  16.295  1.00 40.05 ? 14  ILE   A HG23 1 
ATOM   178   H  HD11 . ILE   A 1 15  ? 16.976  -6.411  15.293  1.00 39.81 ? 14  ILE   A HD11 1 
ATOM   179   H  HD12 . ILE   A 1 15  ? 17.105  -7.943  15.690  1.00 39.81 ? 14  ILE   A HD12 1 
ATOM   180   H  HD13 . ILE   A 1 15  ? 17.723  -7.422  14.323  1.00 39.81 ? 14  ILE   A HD13 1 
ATOM   181   N  N    . ASN   A 1 16  ? 15.216  -11.997 13.300  1.00 26.01 ? 15  ASN   A N    1 
ATOM   182   C  CA   . ASN   A 1 16  ? 14.788  -13.388 13.296  1.00 25.55 ? 15  ASN   A CA   1 
ATOM   183   C  C    . ASN   A 1 16  ? 15.642  -14.142 12.290  1.00 25.23 ? 15  ASN   A C    1 
ATOM   184   O  O    . ASN   A 1 16  ? 15.620  -13.826 11.106  1.00 22.57 ? 15  ASN   A O    1 
ATOM   185   C  CB   . ASN   A 1 16  ? 13.312  -13.424 12.951  1.00 28.07 ? 15  ASN   A CB   1 
ATOM   186   C  CG   . ASN   A 1 16  ? 12.491  -12.649 13.954  1.00 40.71 ? 15  ASN   A CG   1 
ATOM   187   O  OD1  . ASN   A 1 16  ? 12.321  -13.102 15.073  1.00 32.34 ? 15  ASN   A OD1  1 
ATOM   188   N  ND2  . ASN   A 1 16  ? 12.079  -11.430 13.599  1.00 32.54 ? 15  ASN   A ND2  1 
ATOM   189   H  H    . ASN   A 1 16  ? 14.888  -11.545 12.646  1.00 31.21 ? 15  ASN   A H    1 
ATOM   190   H  HA   . ASN   A 1 16  ? 14.917  -13.821 14.154  1.00 30.66 ? 15  ASN   A HA   1 
ATOM   191   H  HB2  . ASN   A 1 16  ? 13.177  -13.029 12.075  1.00 33.68 ? 15  ASN   A HB2  1 
ATOM   192   H  HB3  . ASN   A 1 16  ? 13.004  -14.344 12.950  1.00 33.68 ? 15  ASN   A HB3  1 
ATOM   193   H  HD21 . ASN   A 1 16  ? 12.283  -11.116 12.824  1.00 39.05 ? 15  ASN   A HD21 1 
ATOM   194   H  HD22 . ASN   A 1 16  ? 11.610  -10.959 14.144  1.00 39.05 ? 15  ASN   A HD22 1 
ATOM   195   N  N    . LEU   A 1 17  ? 16.442  -15.084 12.776  1.00 23.98 ? 16  LEU   A N    1 
ATOM   196   C  CA   . LEU   A 1 17  ? 17.369  -15.831 11.929  1.00 21.91 ? 16  LEU   A CA   1 
ATOM   197   C  C    . LEU   A 1 17  ? 16.850  -17.252 11.735  1.00 24.23 ? 16  LEU   A C    1 
ATOM   198   O  O    . LEU   A 1 17  ? 16.407  -17.897 12.694  1.00 24.48 ? 16  LEU   A O    1 
ATOM   199   C  CB   . LEU   A 1 17  ? 18.750  -15.867 12.575  1.00 22.86 ? 16  LEU   A CB   1 
ATOM   200   C  CG   . LEU   A 1 17  ? 19.410  -14.532 12.941  1.00 26.87 ? 16  LEU   A CG   1 
ATOM   201   C  CD1  . LEU   A 1 17  ? 20.813  -14.776 13.461  1.00 24.11 ? 16  LEU   A CD1  1 
ATOM   202   C  CD2  . LEU   A 1 17  ? 19.472  -13.556 11.756  1.00 26.27 ? 16  LEU   A CD2  1 
ATOM   203   H  H    . LEU   A 1 17  ? 16.468  -15.313 13.605  1.00 28.78 ? 16  LEU   A H    1 
ATOM   204   H  HA   . LEU   A 1 17  ? 17.441  -15.414 11.057  1.00 26.29 ? 16  LEU   A HA   1 
ATOM   205   H  HB2  . LEU   A 1 17  ? 18.678  -16.376 13.397  1.00 27.43 ? 16  LEU   A HB2  1 
ATOM   206   H  HB3  . LEU   A 1 17  ? 19.351  -16.315 11.959  1.00 27.43 ? 16  LEU   A HB3  1 
ATOM   207   H  HG   . LEU   A 1 17  ? 18.866  -14.117 13.628  1.00 32.24 ? 16  LEU   A HG   1 
ATOM   208   H  HD11 . LEU   A 1 17  ? 21.148  -13.959 13.862  1.00 28.93 ? 16  LEU   A HD11 1 
ATOM   209   H  HD12 . LEU   A 1 17  ? 20.785  -15.483 14.124  1.00 28.93 ? 16  LEU   A HD12 1 
ATOM   210   H  HD13 . LEU   A 1 17  ? 21.383  -15.039 12.721  1.00 28.93 ? 16  LEU   A HD13 1 
ATOM   211   H  HD21 . LEU   A 1 17  ? 20.209  -12.941 11.892  1.00 31.52 ? 16  LEU   A HD21 1 
ATOM   212   H  HD22 . LEU   A 1 17  ? 19.609  -14.061 10.938  1.00 31.52 ? 16  LEU   A HD22 1 
ATOM   213   H  HD23 . LEU   A 1 17  ? 18.637  -13.066 11.706  1.00 31.52 ? 16  LEU   A HD23 1 
ATOM   214   N  N    . HIS   A 1 18  ? 16.940  -17.758 10.515  1.00 22.91 ? 17  HIS   A N    1 
ATOM   215   C  CA   . HIS   A 1 18  ? 16.368  -19.055 10.171  1.00 26.00 ? 17  HIS   A CA   1 
ATOM   216   C  C    . HIS   A 1 18  ? 17.475  -19.962 9.664   1.00 26.57 ? 17  HIS   A C    1 
ATOM   217   O  O    . HIS   A 1 18  ? 18.069  -19.702 8.615   1.00 22.61 ? 17  HIS   A O    1 
ATOM   218   C  CB   . HIS   A 1 18  ? 15.241  -18.906 9.161   1.00 24.97 ? 17  HIS   A CB   1 
ATOM   219   C  CG   . HIS   A 1 18  ? 14.211  -17.893 9.557   1.00 26.60 ? 17  HIS   A CG   1 
ATOM   220   N  ND1  . HIS   A 1 18  ? 13.300  -18.129 10.567  1.00 31.77 ? 17  HIS   A ND1  1 
ATOM   221   C  CD2  . HIS   A 1 18  ? 13.907  -16.672 9.052   1.00 27.54 ? 17  HIS   A CD2  1 
ATOM   222   C  CE1  . HIS   A 1 18  ? 12.509  -17.077 10.694  1.00 32.24 ? 17  HIS   A CE1  1 
ATOM   223   N  NE2  . HIS   A 1 18  ? 12.850  -16.183 9.782   1.00 30.83 ? 17  HIS   A NE2  1 
ATOM   224   H  H    . HIS   A 1 18  ? 17.334  -17.365 9.859   1.00 27.50 ? 17  HIS   A H    1 
ATOM   225   H  HA   . HIS   A 1 18  ? 15.999  -19.467 10.968  1.00 31.20 ? 17  HIS   A HA   1 
ATOM   226   H  HB2  . HIS   A 1 18  ? 15.618  -18.630 8.311   1.00 29.97 ? 17  HIS   A HB2  1 
ATOM   227   H  HB3  . HIS   A 1 18  ? 14.794  -19.761 9.063   1.00 29.97 ? 17  HIS   A HB3  1 
ATOM   228   H  HD2  . HIS   A 1 18  ? 14.333  -16.246 8.344   1.00 33.05 ? 17  HIS   A HD2  1 
ATOM   229   H  HE1  . HIS   A 1 18  ? 11.827  -16.982 11.320  1.00 38.68 ? 17  HIS   A HE1  1 
ATOM   230   H  HE2  . HIS   A 1 18  ? 12.473  -15.419 9.665   1.00 37.00 ? 17  HIS   A HE2  1 
ATOM   231   N  N    . THR   A 1 19  ? 17.787  -20.996 10.440  1.00 24.45 ? 18  THR   A N    1 
ATOM   232   C  CA   . THR   A 1 19  ? 18.885  -21.886 10.091  1.00 24.62 ? 18  THR   A CA   1 
ATOM   233   C  C    . THR   A 1 19  ? 18.538  -22.622 8.814   1.00 24.64 ? 18  THR   A C    1 
ATOM   234   O  O    . THR   A 1 19  ? 17.424  -23.129 8.676   1.00 26.45 ? 18  THR   A O    1 
ATOM   235   C  CB   . THR   A 1 19  ? 19.160  -22.896 11.206  1.00 29.60 ? 18  THR   A CB   1 
ATOM   236   O  OG1  . THR   A 1 19  ? 19.282  -22.226 12.462  1.00 28.39 ? 18  THR   A OG1  1 
ATOM   237   C  CG2  . THR   A 1 19  ? 20.435  -23.686 10.903  1.00 29.61 ? 18  THR   A CG2  1 
ATOM   238   H  H    . THR   A 1 19  ? 17.379  -21.202 11.169  1.00 29.34 ? 18  THR   A H    1 
ATOM   239   H  HA   . THR   A 1 19  ? 19.691  -21.362 9.965   1.00 29.54 ? 18  THR   A HA   1 
ATOM   240   H  HB   . THR   A 1 19  ? 18.421  -23.523 11.264  1.00 35.52 ? 18  THR   A HB   1 
ATOM   241   H  HG1  . THR   A 1 19  ? 20.091  -22.168 12.679  1.00 34.06 ? 18  THR   A HG1  1 
ATOM   242   H  HG21 . THR   A 1 19  ? 20.780  -24.084 11.717  1.00 35.53 ? 18  THR   A HG21 1 
ATOM   243   H  HG22 . THR   A 1 19  ? 20.245  -24.392 10.265  1.00 35.53 ? 18  THR   A HG22 1 
ATOM   244   H  HG23 . THR   A 1 19  ? 21.109  -23.097 10.529  1.00 35.53 ? 18  THR   A HG23 1 
ATOM   245   N  N    . GLN   A 1 20  ? 19.484  -22.638 7.869   1.00 24.71 ? 19  GLN   A N    1 
ATOM   246   C  CA   . GLN   A 1 20  ? 19.356  -23.370 6.619   1.00 25.19 ? 19  GLN   A CA   1 
ATOM   247   C  C    . GLN   A 1 20  ? 20.561  -24.280 6.446   1.00 30.78 ? 19  GLN   A C    1 
ATOM   248   O  O    . GLN   A 1 20  ? 21.681  -23.951 6.856   1.00 29.59 ? 19  GLN   A O    1 
ATOM   249   C  CB   . GLN   A 1 20  ? 19.282  -22.457 5.412   1.00 25.62 ? 19  GLN   A CB   1 
ATOM   250   C  CG   . GLN   A 1 20  ? 18.227  -21.360 5.406   1.00 28.21 ? 19  GLN   A CG   1 
ATOM   251   C  CD   . GLN   A 1 20  ? 16.836  -21.890 5.584   1.00 34.16 ? 19  GLN   A CD   1 
ATOM   252   O  OE1  . GLN   A 1 20  ? 16.529  -23.005 5.160   1.00 30.97 ? 19  GLN   A OE1  1 
ATOM   253   N  NE2  . GLN   A 1 20  ? 15.949  -21.055 6.118   1.00 31.86 ? 19  GLN   A NE2  1 
ATOM   254   H  H    . GLN   A 1 20  ? 20.230  -22.216 7.938   1.00 29.65 ? 19  GLN   A H    1 
ATOM   255   H  HA   . GLN   A 1 20  ? 18.543  -23.898 6.657   1.00 30.23 ? 19  GLN   A HA   1 
ATOM   256   H  HB2  . GLN   A 1 20  ? 20.141  -22.016 5.323   1.00 30.74 ? 19  GLN   A HB2  1 
ATOM   257   H  HB3  . GLN   A 1 20  ? 19.110  -23.010 4.634   1.00 30.74 ? 19  GLN   A HB3  1 
ATOM   258   H  HG2  . GLN   A 1 20  ? 18.408  -20.743 6.133   1.00 33.86 ? 19  GLN   A HG2  1 
ATOM   259   H  HG3  . GLN   A 1 20  ? 18.262  -20.892 4.557   1.00 33.86 ? 19  GLN   A HG3  1 
ATOM   260   H  HE21 . GLN   A 1 20  ? 16.187  -20.259 6.340   1.00 38.24 ? 19  GLN   A HE21 1 
ATOM   261   H  HE22 . GLN   A 1 20  ? 15.137  -21.311 6.242   1.00 38.24 ? 19  GLN   A HE22 1 
ATOM   262   N  N    . VAL   A 1 21  ? 20.328  -25.432 5.824   1.00 30.17 ? 20  VAL   A N    1 
ATOM   263   C  CA   . VAL   A 1 21  ? 21.418  -26.287 5.377   1.00 35.54 ? 20  VAL   A CA   1 
ATOM   264   C  C    . VAL   A 1 21  ? 21.520  -26.089 3.877   1.00 28.40 ? 20  VAL   A C    1 
ATOM   265   O  O    . VAL   A 1 21  ? 20.527  -26.273 3.165   1.00 35.73 ? 20  VAL   A O    1 
ATOM   266   C  CB   . VAL   A 1 21  ? 21.170  -27.763 5.727   1.00 36.17 ? 20  VAL   A CB   1 
ATOM   267   C  CG1  . VAL   A 1 21  ? 22.102  -28.646 4.880   1.00 42.30 ? 20  VAL   A CG1  1 
ATOM   268   C  CG2  . VAL   A 1 21  ? 21.372  -28.015 7.228   1.00 38.08 ? 20  VAL   A CG2  1 
ATOM   269   N  N    . VAL   A 1 22  ? 22.686  -25.670 3.388   1.00 28.96 ? 21  VAL   A N    1 
ATOM   270   C  CA   . VAL   A 1 22  ? 22.838  -25.315 1.984   1.00 29.71 ? 21  VAL   A CA   1 
ATOM   271   C  C    . VAL   A 1 22  ? 23.721  -26.345 1.295   1.00 29.50 ? 21  VAL   A C    1 
ATOM   272   O  O    . VAL   A 1 22  ? 24.756  -26.759 1.823   1.00 30.75 ? 21  VAL   A O    1 
ATOM   273   C  CB   . VAL   A 1 22  ? 23.403  -23.893 1.767   1.00 34.93 ? 21  VAL   A CB   1 
ATOM   274   C  CG1  . VAL   A 1 22  ? 22.657  -22.879 2.634   1.00 43.38 ? 21  VAL   A CG1  1 
ATOM   275   C  CG2  . VAL   A 1 22  ? 24.867  -23.836 2.048   1.00 40.24 ? 21  VAL   A CG2  1 
ATOM   276   N  N    . ASP   A 1 23  ? 23.299  -26.734 0.098   1.00 31.30 ? 22  ASP   A N    1 
ATOM   277   C  CA   . ASP   A 1 23  ? 24.017  -27.647 -0.789  1.00 30.60 ? 22  ASP   A CA   1 
ATOM   278   C  C    . ASP   A 1 23  ? 25.070  -26.848 -1.556  1.00 24.44 ? 22  ASP   A C    1 
ATOM   279   O  O    . ASP   A 1 23  ? 24.748  -25.923 -2.300  1.00 31.98 ? 22  ASP   A O    1 
ATOM   280   C  CB   . ASP   A 1 23  ? 22.989  -28.341 -1.685  1.00 31.63 ? 22  ASP   A CB   1 
ATOM   281   C  CG   . ASP   A 1 23  ? 23.603  -29.255 -2.742  1.00 32.33 ? 22  ASP   A CG   1 
ATOM   282   O  OD1  . ASP   A 1 23  ? 24.823  -29.218 -2.988  1.00 31.11 ? 22  ASP   A OD1  1 
ATOM   283   O  OD2  . ASP   A 1 23  ? 22.824  -30.075 -3.270  1.00 33.14 ? 22  ASP   A OD2  1 
ATOM   284   N  N    . MET   A 1 24  ? 26.347  -27.149 -1.312  1.00 26.54 ? 23  MET   A N    1 
ATOM   285   C  CA   . MET   A 1 24  ? 27.424  -26.360 -1.893  1.00 27.85 ? 23  MET   A CA   1 
ATOM   286   C  C    . MET   A 1 24  ? 27.564  -26.573 -3.391  1.00 35.09 ? 23  MET   A C    1 
ATOM   287   O  O    . MET   A 1 24  ? 28.290  -25.818 -4.045  1.00 35.43 ? 23  MET   A O    1 
ATOM   288   C  CB   . MET   A 1 24  ? 28.738  -26.720 -1.185  1.00 26.66 ? 23  MET   A CB   1 
ATOM   289   C  CG   . MET   A 1 24  ? 28.603  -26.705 0.357   1.00 33.45 ? 23  MET   A CG   1 
ATOM   290   S  SD   . MET   A 1 24  ? 30.182  -26.628 1.220   1.00 36.85 ? 23  MET   A SD   1 
ATOM   291   C  CE   . MET   A 1 24  ? 30.909  -25.165 0.447   1.00 34.06 ? 23  MET   A CE   1 
ATOM   292   N  N    . SER   A 1 25  ? 26.898  -27.580 -3.943  1.00 33.98 ? 24  SER   A N    1 
ATOM   293   C  CA   . SER   A 1 25  ? 26.913  -27.813 -5.386  1.00 36.51 ? 24  SER   A CA   1 
ATOM   294   C  C    . SER   A 1 25  ? 25.870  -26.993 -6.141  1.00 43.62 ? 24  SER   A C    1 
ATOM   295   O  O    . SER   A 1 25  ? 25.835  -27.042 -7.375  1.00 39.33 ? 24  SER   A O    1 
ATOM   296   C  CB   . SER   A 1 25  ? 26.747  -29.311 -5.656  1.00 36.67 ? 24  SER   A CB   1 
ATOM   297   O  OG   . SER   A 1 25  ? 25.396  -29.713 -5.566  1.00 35.63 ? 24  SER   A OG   1 
ATOM   298   N  N    . MET   A 1 26  ? 25.065  -26.185 -5.448  1.00 32.71 ? 25  MET   A N    1 
ATOM   299   C  CA   . MET   A 1 26  ? 24.069  -25.341 -6.099  1.00 34.53 ? 25  MET   A CA   1 
ATOM   300   C  C    . MET   A 1 26  ? 24.288  -23.887 -5.698  1.00 38.50 ? 25  MET   A C    1 
ATOM   301   O  O    . MET   A 1 26  ? 24.888  -23.598 -4.656  1.00 32.49 ? 25  MET   A O    1 
ATOM   302   C  CB   . MET   A 1 26  ? 22.668  -25.775 -5.685  1.00 33.05 ? 25  MET   A CB   1 
ATOM   303   C  CG   . MET   A 1 26  ? 22.283  -27.199 -6.085  1.00 33.84 ? 25  MET   A CG   1 
ATOM   304   S  SD   . MET   A 1 26  ? 20.848  -27.825 -5.165  1.00 42.06 ? 25  MET   A SD   1 
ATOM   305   C  CE   . MET   A 1 26  ? 19.610  -26.689 -5.783  1.00 45.84 ? 25  MET   A CE   1 
ATOM   306   H  H    . MET   A 1 26  ? 25.079  -26.110 -4.591  1.00 39.25 ? 25  MET   A H    1 
ATOM   307   H  HA   . MET   A 1 26  ? 24.153  -25.411 -7.063  1.00 41.44 ? 25  MET   A HA   1 
ATOM   308   H  HB2  . MET   A 1 26  ? 22.603  -25.718 -4.719  1.00 39.66 ? 25  MET   A HB2  1 
ATOM   309   H  HB3  . MET   A 1 26  ? 22.027  -25.175 -6.098  1.00 39.66 ? 25  MET   A HB3  1 
ATOM   310   H  HG2  . MET   A 1 26  ? 22.063  -27.213 -7.030  1.00 40.61 ? 25  MET   A HG2  1 
ATOM   311   H  HG3  . MET   A 1 26  ? 23.032  -27.789 -5.910  1.00 40.61 ? 25  MET   A HG3  1 
ATOM   312   H  HE1  . MET   A 1 26  ? 18.729  -27.054 -5.604  1.00 55.01 ? 25  MET   A HE1  1 
ATOM   313   H  HE2  . MET   A 1 26  ? 19.712  -25.836 -5.333  1.00 55.01 ? 25  MET   A HE2  1 
ATOM   314   H  HE3  . MET   A 1 26  ? 19.734  -26.576 -6.739  1.00 55.01 ? 25  MET   A HE3  1 
ATOM   315   N  N    . THR   A 1 27  ? 23.803  -22.961 -6.524  1.00 31.09 ? 26  THR   A N    1 
ATOM   316   C  CA   . THR   A 1 27  ? 23.941  -21.556 -6.155  1.00 37.43 ? 26  THR   A CA   1 
ATOM   317   C  C    . THR   A 1 27  ? 22.920  -21.193 -5.069  1.00 24.33 ? 26  THR   A C    1 
ATOM   318   O  O    . THR   A 1 27  ? 21.899  -21.854 -4.903  1.00 26.60 ? 26  THR   A O    1 
ATOM   319   C  CB   . THR   A 1 27  ? 23.723  -20.628 -7.347  1.00 31.98 ? 26  THR   A CB   1 
ATOM   320   O  OG1  . THR   A 1 27  ? 22.352  -20.707 -7.732  1.00 33.74 ? 26  THR   A OG1  1 
ATOM   321   C  CG2  . THR   A 1 27  ? 24.620  -21.008 -8.524  1.00 40.60 ? 26  THR   A CG2  1 
ATOM   322   H  H    . THR   A 1 27  ? 23.408  -23.115 -7.272  1.00 37.31 ? 26  THR   A H    1 
ATOM   323   H  HA   . THR   A 1 27  ? 24.844  -21.418 -5.827  1.00 44.91 ? 26  THR   A HA   1 
ATOM   324   H  HB   . THR   A 1 27  ? 23.950  -19.717 -7.102  1.00 38.38 ? 26  THR   A HB   1 
ATOM   325   H  HG1  . THR   A 1 27  ? 22.024  -19.935 -7.787  1.00 40.49 ? 26  THR   A HG1  1 
ATOM   326   H  HG21 . THR   A 1 27  ? 24.725  -20.250 -9.120  1.00 48.72 ? 26  THR   A HG21 1 
ATOM   327   H  HG22 . THR   A 1 27  ? 25.494  -21.278 -8.202  1.00 48.72 ? 26  THR   A HG22 1 
ATOM   328   H  HG23 . THR   A 1 27  ? 24.226  -21.744 -9.018  1.00 48.72 ? 26  THR   A HG23 1 
ATOM   329   N  N    . TYR   A 1 28  ? 23.185  -20.086 -4.355  1.00 29.29 ? 27  TYR   A N    1 
ATOM   330   C  CA   . TYR   A 1 28  ? 22.210  -19.602 -3.383  1.00 28.20 ? 27  TYR   A CA   1 
ATOM   331   C  C    . TYR   A 1 28  ? 20.859  -19.338 -4.051  1.00 28.32 ? 27  TYR   A C    1 
ATOM   332   O  O    . TYR   A 1 28  ? 19.807  -19.710 -3.519  1.00 27.39 ? 27  TYR   A O    1 
ATOM   333   C  CB   . TYR   A 1 28  ? 22.732  -18.320 -2.705  1.00 27.58 ? 27  TYR   A CB   1 
ATOM   334   C  CG   . TYR   A 1 28  ? 23.814  -18.582 -1.690  1.00 26.92 ? 27  TYR   A CG   1 
ATOM   335   C  CD1  . TYR   A 1 28  ? 23.518  -19.194 -0.475  1.00 24.65 ? 27  TYR   A CD1  1 
ATOM   336   C  CD2  . TYR   A 1 28  ? 25.131  -18.249 -1.949  1.00 26.54 ? 27  TYR   A CD2  1 
ATOM   337   C  CE1  . TYR   A 1 28  ? 24.495  -19.450 0.448   1.00 25.24 ? 27  TYR   A CE1  1 
ATOM   338   C  CE2  . TYR   A 1 28  ? 26.125  -18.509 -1.026  1.00 27.17 ? 27  TYR   A CE2  1 
ATOM   339   C  CZ   . TYR   A 1 28  ? 25.795  -19.126 0.176   1.00 23.65 ? 27  TYR   A CZ   1 
ATOM   340   O  OH   . TYR   A 1 28  ? 26.770  -19.407 1.101   1.00 27.69 ? 27  TYR   A OH   1 
ATOM   341   H  H    . TYR   A 1 28  ? 23.903  -19.616 -4.416  1.00 35.15 ? 27  TYR   A H    1 
ATOM   342   H  HA   . TYR   A 1 28  ? 22.085  -20.277 -2.698  1.00 33.84 ? 27  TYR   A HA   1 
ATOM   343   H  HB2  . TYR   A 1 28  ? 23.097  -17.732 -3.384  1.00 33.09 ? 27  TYR   A HB2  1 
ATOM   344   H  HB3  . TYR   A 1 28  ? 21.995  -17.884 -2.249  1.00 33.09 ? 27  TYR   A HB3  1 
ATOM   345   H  HD1  . TYR   A 1 28  ? 22.639  -19.434 -0.287  1.00 29.57 ? 27  TYR   A HD1  1 
ATOM   346   H  HD2  . TYR   A 1 28  ? 25.351  -17.843 -2.757  1.00 31.84 ? 27  TYR   A HD2  1 
ATOM   347   H  HE1  . TYR   A 1 28  ? 24.275  -19.844 1.261   1.00 30.29 ? 27  TYR   A HE1  1 
ATOM   348   H  HE2  . TYR   A 1 28  ? 27.007  -18.275 -1.207  1.00 32.60 ? 27  TYR   A HE2  1 
ATOM   349   H  HH   . TYR   A 1 28  ? 26.457  -19.341 1.878   1.00 33.23 ? 27  TYR   A HH   1 
ATOM   350   N  N    . GLY   A 1 29  ? 20.869  -18.729 -5.240  1.00 27.15 ? 28  GLY   A N    1 
ATOM   351   C  CA   . GLY   A 1 29  ? 19.620  -18.461 -5.935  1.00 33.25 ? 28  GLY   A CA   1 
ATOM   352   C  C    . GLY   A 1 29  ? 18.801  -19.709 -6.226  1.00 35.40 ? 28  GLY   A C    1 
ATOM   353   O  O    . GLY   A 1 29  ? 17.572  -19.677 -6.154  1.00 30.35 ? 28  GLY   A O    1 
ATOM   354   H  H    . GLY   A 1 29  ? 21.575  -18.468 -5.656  1.00 32.58 ? 28  GLY   A H    1 
ATOM   355   H  HA2  . GLY   A 1 29  ? 19.078  -17.867 -5.392  1.00 39.90 ? 28  GLY   A HA2  1 
ATOM   356   H  HA3  . GLY   A 1 29  ? 19.816  -18.027 -6.779  1.00 39.90 ? 28  GLY   A HA3  1 
ATOM   357   N  N    . GLN   A 1 30  ? 19.468  -20.827 -6.551  1.00 36.44 ? 29  GLN   A N    1 
ATOM   358   C  CA   . GLN   A 1 30  ? 18.757  -22.083 -6.795  1.00 31.56 ? 29  GLN   A CA   1 
ATOM   359   C  C    . GLN   A 1 30  ? 18.111  -22.642 -5.542  1.00 37.12 ? 29  GLN   A C    1 
ATOM   360   O  O    . GLN   A 1 30  ? 17.204  -23.480 -5.629  1.00 36.33 ? 29  GLN   A O    1 
ATOM   361   C  CB   . GLN   A 1 30  ? 19.722  -23.118 -7.377  1.00 37.91 ? 29  GLN   A CB   1 
ATOM   362   C  CG   . GLN   A 1 30  ? 20.040  -22.882 -8.823  1.00 35.83 ? 29  GLN   A CG   1 
ATOM   363   C  CD   . GLN   A 1 30  ? 21.184  -23.730 -9.360  1.00 45.02 ? 29  GLN   A CD   1 
ATOM   364   O  OE1  . GLN   A 1 30  ? 22.104  -24.115 -8.635  1.00 34.40 ? 29  GLN   A OE1  1 
ATOM   365   N  NE2  . GLN   A 1 30  ? 21.124  -24.028 -10.653 1.00 51.46 ? 29  GLN   A NE2  1 
ATOM   366   H  H    . GLN   A 1 30  ? 20.322  -20.881 -6.636  1.00 43.73 ? 29  GLN   A H    1 
ATOM   367   H  HA   . GLN   A 1 30  ? 18.054  -21.918 -7.442  1.00 37.87 ? 29  GLN   A HA   1 
ATOM   368   H  HB2  . GLN   A 1 30  ? 20.555  -23.085 -6.879  1.00 45.49 ? 29  GLN   A HB2  1 
ATOM   369   H  HB3  . GLN   A 1 30  ? 19.323  -23.998 -7.298  1.00 45.49 ? 29  GLN   A HB3  1 
ATOM   370   H  HG2  . GLN   A 1 30  ? 19.252  -23.086 -9.351  1.00 43.00 ? 29  GLN   A HG2  1 
ATOM   371   H  HG3  . GLN   A 1 30  ? 20.285  -21.951 -8.939  1.00 43.00 ? 29  GLN   A HG3  1 
ATOM   372   H  HE21 . GLN   A 1 30  ? 20.467  -23.744 -11.130 1.00 61.75 ? 29  GLN   A HE21 1 
ATOM   373   H  HE22 . GLN   A 1 30  ? 21.743  -24.505 -11.014 1.00 61.75 ? 29  GLN   A HE22 1 
ATOM   374   N  N    . GLN   A 1 31  ? 18.563  -22.207 -4.378  1.00 27.44 ? 30  GLN   A N    1 
ATOM   375   C  CA   . GLN   A 1 31  ? 18.073  -22.732 -3.121  1.00 31.44 ? 30  GLN   A CA   1 
ATOM   376   C  C    . GLN   A 1 31  ? 17.178  -21.758 -2.393  1.00 31.19 ? 30  GLN   A C    1 
ATOM   377   O  O    . GLN   A 1 31  ? 16.234  -22.193 -1.741  1.00 33.49 ? 30  GLN   A O    1 
ATOM   378   C  CB   . GLN   A 1 31  ? 19.265  -23.091 -2.226  1.00 35.55 ? 30  GLN   A CB   1 
ATOM   379   C  CG   . GLN   A 1 31  ? 20.160  -24.120 -2.886  1.00 29.45 ? 30  GLN   A CG   1 
ATOM   380   C  CD   . GLN   A 1 31  ? 21.366  -24.483 -2.070  1.00 25.09 ? 30  GLN   A CD   1 
ATOM   381   O  OE1  . GLN   A 1 31  ? 21.267  -25.196 -1.060  1.00 29.47 ? 30  GLN   A OE1  1 
ATOM   382   N  NE2  . GLN   A 1 31  ? 22.523  -24.007 -2.503  1.00 28.01 ? 30  GLN   A NE2  1 
ATOM   383   H  H    . GLN   A 1 31  ? 19.163  -21.598 -4.290  1.00 32.93 ? 30  GLN   A H    1 
ATOM   384   H  HA   . GLN   A 1 31  ? 17.562  -23.542 -3.273  1.00 37.72 ? 30  GLN   A HA   1 
ATOM   385   H  HB2  . GLN   A 1 31  ? 19.790  -22.293 -2.055  1.00 42.65 ? 30  GLN   A HB2  1 
ATOM   386   H  HB3  . GLN   A 1 31  ? 18.939  -23.459 -1.390  1.00 42.65 ? 30  GLN   A HB3  1 
ATOM   387   H  HG2  . GLN   A 1 31  ? 19.648  -24.930 -3.034  1.00 35.35 ? 30  GLN   A HG2  1 
ATOM   388   H  HG3  . GLN   A 1 31  ? 20.472  -23.765 -3.733  1.00 35.35 ? 30  GLN   A HG3  1 
ATOM   389   H  HE21 . GLN   A 1 31  ? 22.551  -23.522 -3.212  1.00 33.61 ? 30  GLN   A HE21 1 
ATOM   390   H  HE22 . GLN   A 1 31  ? 23.248  -24.184 -2.074  1.00 33.61 ? 30  GLN   A HE22 1 
ATOM   391   N  N    . PHE   A 1 32  ? 17.442  -20.450 -2.516  1.00 32.17 ? 31  PHE   A N    1 
ATOM   392   C  CA   . PHE   A 1 32  ? 16.732  -19.443 -1.742  1.00 33.57 ? 31  PHE   A CA   1 
ATOM   393   C  C    . PHE   A 1 32  ? 15.996  -18.412 -2.589  1.00 31.15 ? 31  PHE   A C    1 
ATOM   394   O  O    . PHE   A 1 32  ? 15.170  -17.671 -2.045  1.00 34.07 ? 31  PHE   A O    1 
ATOM   395   C  CB   . PHE   A 1 32  ? 17.688  -18.634 -0.836  1.00 29.31 ? 31  PHE   A CB   1 
ATOM   396   C  CG   . PHE   A 1 32  ? 18.440  -19.434 0.205   1.00 31.75 ? 31  PHE   A CG   1 
ATOM   397   C  CD1  . PHE   A 1 32  ? 17.913  -20.579 0.772   1.00 32.97 ? 31  PHE   A CD1  1 
ATOM   398   C  CD2  . PHE   A 1 32  ? 19.665  -18.967 0.668   1.00 36.15 ? 31  PHE   A CD2  1 
ATOM   399   C  CE1  . PHE   A 1 32  ? 18.624  -21.281 1.745   1.00 29.85 ? 31  PHE   A CE1  1 
ATOM   400   C  CE2  . PHE   A 1 32  ? 20.372  -19.659 1.647   1.00 37.47 ? 31  PHE   A CE2  1 
ATOM   401   C  CZ   . PHE   A 1 32  ? 19.849  -20.814 2.178   1.00 30.86 ? 31  PHE   A CZ   1 
ATOM   402   H  H    . PHE   A 1 32  ? 18.035  -20.126 -3.048  1.00 38.61 ? 31  PHE   A H    1 
ATOM   403   H  HA   . PHE   A 1 32  ? 16.101  -19.921 -1.182  1.00 40.28 ? 31  PHE   A HA   1 
ATOM   404   H  HB2  . PHE   A 1 32  ? 18.349  -18.203 -1.400  1.00 35.17 ? 31  PHE   A HB2  1 
ATOM   405   H  HB3  . PHE   A 1 32  ? 17.168  -17.965 -0.365  1.00 35.17 ? 31  PHE   A HB3  1 
ATOM   406   H  HD1  . PHE   A 1 32  ? 17.076  -20.884 0.503   1.00 39.56 ? 31  PHE   A HD1  1 
ATOM   407   H  HD2  . PHE   A 1 32  ? 20.017  -18.180 0.318   1.00 43.38 ? 31  PHE   A HD2  1 
ATOM   408   H  HE1  . PHE   A 1 32  ? 18.273  -22.065 2.102   1.00 35.82 ? 31  PHE   A HE1  1 
ATOM   409   H  HE2  . PHE   A 1 32  ? 21.196  -19.342 1.940   1.00 44.97 ? 31  PHE   A HE2  1 
ATOM   410   H  HZ   . PHE   A 1 32  ? 20.320  -21.281 2.830   1.00 37.03 ? 31  PHE   A HZ   1 
ATOM   411   N  N    . GLY   A 1 33  ? 16.313  -18.296 -3.866  1.00 31.95 ? 32  GLY   A N    1 
ATOM   412   C  CA   . GLY   A 1 33  ? 15.972  -17.117 -4.623  1.00 33.50 ? 32  GLY   A CA   1 
ATOM   413   C  C    . GLY   A 1 33  ? 17.027  -16.041 -4.432  1.00 32.80 ? 32  GLY   A C    1 
ATOM   414   O  O    . GLY   A 1 33  ? 18.156  -16.315 -4.000  1.00 29.95 ? 32  GLY   A O    1 
ATOM   415   H  H    . GLY   A 1 33  ? 16.730  -18.897 -4.319  1.00 38.34 ? 32  GLY   A H    1 
ATOM   416   H  HA2  . GLY   A 1 33  ? 15.915  -17.337 -5.567  1.00 40.20 ? 32  GLY   A HA2  1 
ATOM   417   H  HA3  . GLY   A 1 33  ? 15.115  -16.772 -4.327  1.00 40.20 ? 32  GLY   A HA3  1 
ATOM   418   N  N    . PRO   A 1 34  ? 16.688  -14.796 -4.761  1.00 31.42 ? 33  PRO   A N    1 
ATOM   419   C  CA   . PRO   A 1 34  ? 17.654  -13.704 -4.596  1.00 29.36 ? 33  PRO   A CA   1 
ATOM   420   C  C    . PRO   A 1 34  ? 18.181  -13.670 -3.167  1.00 25.79 ? 33  PRO   A C    1 
ATOM   421   O  O    . PRO   A 1 34  ? 17.412  -13.729 -2.200  1.00 28.60 ? 33  PRO   A O    1 
ATOM   422   C  CB   . PRO   A 1 34  ? 16.831  -12.455 -4.941  1.00 35.73 ? 33  PRO   A CB   1 
ATOM   423   C  CG   . PRO   A 1 34  ? 15.768  -12.989 -5.920  1.00 32.74 ? 33  PRO   A CG   1 
ATOM   424   C  CD   . PRO   A 1 34  ? 15.398  -14.322 -5.299  1.00 34.16 ? 33  PRO   A CD   1 
ATOM   425   H  HA   . PRO   A 1 34  ? 18.392  -13.782 -5.220  1.00 35.23 ? 33  PRO   A HA   1 
ATOM   426   H  HB2  . PRO   A 1 34  ? 16.423  -12.089 -4.141  1.00 42.87 ? 33  PRO   A HB2  1 
ATOM   427   H  HB3  . PRO   A 1 34  ? 17.394  -11.786 -5.361  1.00 42.87 ? 33  PRO   A HB3  1 
ATOM   428   H  HG2  . PRO   A 1 34  ? 15.006  -12.389 -5.956  1.00 39.29 ? 33  PRO   A HG2  1 
ATOM   429   H  HG3  . PRO   A 1 34  ? 16.145  -13.100 -6.806  1.00 39.29 ? 33  PRO   A HG3  1 
ATOM   430   H  HD2  . PRO   A 1 34  ? 14.747  -14.207 -4.590  1.00 40.99 ? 33  PRO   A HD2  1 
ATOM   431   H  HD3  . PRO   A 1 34  ? 15.055  -14.934 -5.969  1.00 40.99 ? 33  PRO   A HD3  1 
ATOM   432   N  N    . THR   A 1 35  ? 19.506  -13.591 -3.041  1.00 28.36 ? 34  THR   A N    1 
ATOM   433   C  CA   . THR   A 1 35  ? 20.189  -13.765 -1.765  1.00 26.49 ? 34  THR   A CA   1 
ATOM   434   C  C    . THR   A 1 35  ? 21.317  -12.757 -1.690  1.00 26.91 ? 34  THR   A C    1 
ATOM   435   O  O    . THR   A 1 35  ? 22.026  -12.548 -2.684  1.00 26.82 ? 34  THR   A O    1 
ATOM   436   C  CB   . THR   A 1 35  ? 20.778  -15.183 -1.622  1.00 28.42 ? 34  THR   A CB   1 
ATOM   437   O  OG1  . THR   A 1 35  ? 19.744  -16.138 -1.826  1.00 28.59 ? 34  THR   A OG1  1 
ATOM   438   C  CG2  . THR   A 1 35  ? 21.366  -15.393 -0.217  1.00 29.39 ? 34  THR   A CG2  1 
ATOM   439   H  H    . THR   A 1 35  ? 20.040  -13.435 -3.697  1.00 34.03 ? 34  THR   A H    1 
ATOM   440   H  HA   . THR   A 1 35  ? 19.564  -13.616 -1.038  1.00 31.79 ? 34  THR   A HA   1 
ATOM   441   H  HB   . THR   A 1 35  ? 21.486  -15.305 -2.273  1.00 34.11 ? 34  THR   A HB   1 
ATOM   442   H  HG1  . THR   A 1 35  ? 20.074  -16.907 -1.901  1.00 34.31 ? 34  THR   A HG1  1 
ATOM   443   H  HG21 . THR   A 1 35  ? 21.440  -16.342 -0.027  1.00 35.27 ? 34  THR   A HG21 1 
ATOM   444   H  HG22 . THR   A 1 35  ? 22.248  -14.992 -0.164  1.00 35.27 ? 34  THR   A HG22 1 
ATOM   445   H  HG23 . THR   A 1 35  ? 20.792  -14.982 0.448   1.00 35.27 ? 34  THR   A HG23 1 
ATOM   446   N  N    . TYR   A 1 36  ? 21.518  -12.181 -0.500  1.00 22.69 ? 35  TYR   A N    1 
ATOM   447   C  CA   . TYR   A 1 36  ? 22.481  -11.114 -0.292  1.00 25.10 ? 35  TYR   A CA   1 
ATOM   448   C  C    . TYR   A 1 36  ? 23.324  -11.364 0.946   1.00 23.96 ? 35  TYR   A C    1 
ATOM   449   O  O    . TYR   A 1 36  ? 22.819  -11.811 1.982   1.00 25.89 ? 35  TYR   A O    1 
ATOM   450   C  CB   . TYR   A 1 36  ? 21.775  -9.746  -0.132  1.00 27.99 ? 35  TYR   A CB   1 
ATOM   451   C  CG   . TYR   A 1 36  ? 20.854  -9.429  -1.269  1.00 25.49 ? 35  TYR   A CG   1 
ATOM   452   C  CD1  . TYR   A 1 36  ? 19.569  -9.923  -1.289  1.00 25.19 ? 35  TYR   A CD1  1 
ATOM   453   C  CD2  . TYR   A 1 36  ? 21.278  -8.650  -2.331  1.00 29.40 ? 35  TYR   A CD2  1 
ATOM   454   C  CE1  . TYR   A 1 36  ? 18.729  -9.657  -2.343  1.00 29.21 ? 35  TYR   A CE1  1 
ATOM   455   C  CE2  . TYR   A 1 36  ? 20.453  -8.361  -3.372  1.00 28.13 ? 35  TYR   A CE2  1 
ATOM   456   C  CZ   . TYR   A 1 36  ? 19.183  -8.862  -3.384  1.00 35.53 ? 35  TYR   A CZ   1 
ATOM   457   O  OH   . TYR   A 1 36  ? 18.353  -8.579  -4.446  1.00 37.71 ? 35  TYR   A OH   1 
ATOM   458   H  H    . TYR   A 1 36  ? 21.094  -12.402 0.215   1.00 27.23 ? 35  TYR   A H    1 
ATOM   459   H  HA   . TYR   A 1 36  ? 23.073  -11.095 -1.060  1.00 30.12 ? 35  TYR   A HA   1 
ATOM   460   H  HB2  . TYR   A 1 36  ? 21.252  -9.755  0.684   1.00 33.58 ? 35  TYR   A HB2  1 
ATOM   461   H  HB3  . TYR   A 1 36  ? 22.448  -9.048  -0.087  1.00 33.58 ? 35  TYR   A HB3  1 
ATOM   462   H  HD1  . TYR   A 1 36  ? 19.266  -10.444 -0.581  1.00 30.23 ? 35  TYR   A HD1  1 
ATOM   463   H  HD2  . TYR   A 1 36  ? 22.146  -8.317  -2.333  1.00 35.28 ? 35  TYR   A HD2  1 
ATOM   464   H  HE1  . TYR   A 1 36  ? 17.867  -10.005 -2.358  1.00 35.05 ? 35  TYR   A HE1  1 
ATOM   465   H  HE2  . TYR   A 1 36  ? 20.752  -7.826  -4.072  1.00 33.75 ? 35  TYR   A HE2  1 
ATOM   466   H  HH   . TYR   A 1 36  ? 18.041  -7.803  -4.368  1.00 45.25 ? 35  TYR   A HH   1 
ATOM   467   N  N    . LEU   A 1 37  ? 24.599  -11.008 0.853   1.00 23.29 ? 36  LEU   A N    1 
ATOM   468   C  CA   . LEU   A 1 37  ? 25.535  -11.095 1.967   1.00 22.99 ? 36  LEU   A CA   1 
ATOM   469   C  C    . LEU   A 1 37  ? 26.106  -9.704  2.237   1.00 31.64 ? 36  LEU   A C    1 
ATOM   470   O  O    . LEU   A 1 37  ? 26.881  -9.167  1.430   1.00 27.25 ? 36  LEU   A O    1 
ATOM   471   C  CB   . LEU   A 1 37  ? 26.651  -12.086 1.676   1.00 26.52 ? 36  LEU   A CB   1 
ATOM   472   C  CG   . LEU   A 1 37  ? 27.636  -12.372 2.817   1.00 25.36 ? 36  LEU   A CG   1 
ATOM   473   C  CD1  . LEU   A 1 37  ? 26.916  -12.857 4.076   1.00 26.43 ? 36  LEU   A CD1  1 
ATOM   474   C  CD2  . LEU   A 1 37  ? 28.690  -13.372 2.343   1.00 32.44 ? 36  LEU   A CD2  1 
ATOM   475   H  H    . LEU   A 1 37  ? 24.957  -10.704 0.132   1.00 27.94 ? 36  LEU   A H    1 
ATOM   476   H  HA   . LEU   A 1 37  ? 25.055  -11.391 2.757   1.00 27.58 ? 36  LEU   A HA   1 
ATOM   477   H  HB2  . LEU   A 1 37  ? 26.244  -12.933 1.433   1.00 31.83 ? 36  LEU   A HB2  1 
ATOM   478   H  HB3  . LEU   A 1 37  ? 27.171  -11.742 0.932   1.00 31.83 ? 36  LEU   A HB3  1 
ATOM   479   H  HG   . LEU   A 1 37  ? 28.087  -11.550 3.067   1.00 30.44 ? 36  LEU   A HG   1 
ATOM   480   H  HD11 . LEU   A 1 37  ? 27.521  -13.411 4.592   1.00 31.72 ? 36  LEU   A HD11 1 
ATOM   481   H  HD12 . LEU   A 1 37  ? 26.644  -12.087 4.600   1.00 31.72 ? 36  LEU   A HD12 1 
ATOM   482   H  HD13 . LEU   A 1 37  ? 26.136  -13.371 3.815   1.00 31.72 ? 36  LEU   A HD13 1 
ATOM   483   H  HD21 . LEU   A 1 37  ? 29.489  -13.269 2.883   1.00 38.93 ? 36  LEU   A HD21 1 
ATOM   484   H  HD22 . LEU   A 1 37  ? 28.338  -14.271 2.440   1.00 38.93 ? 36  LEU   A HD22 1 
ATOM   485   H  HD23 . LEU   A 1 37  ? 28.896  -13.196 1.411   1.00 38.93 ? 36  LEU   A HD23 1 
ATOM   486   N  N    . ASP   A 1 38  ? 25.733  -9.135  3.379   1.00 31.41 ? 37  ASP   A N    1 
ATOM   487   C  CA   . ASP   A 1 38  ? 26.112  -7.770  3.733   1.00 30.45 ? 37  ASP   A CA   1 
ATOM   488   C  C    . ASP   A 1 38  ? 25.933  -6.834  2.540   1.00 27.97 ? 37  ASP   A C    1 
ATOM   489   O  O    . ASP   A 1 38  ? 26.798  -5.997  2.259   1.00 31.34 ? 37  ASP   A O    1 
ATOM   490   C  CB   . ASP   A 1 38  ? 27.551  -7.690  4.240   1.00 33.46 ? 37  ASP   A CB   1 
ATOM   491   C  CG   . ASP   A 1 38  ? 27.765  -6.497  5.202   1.00 49.11 ? 37  ASP   A CG   1 
ATOM   492   O  OD1  . ASP   A 1 38  ? 28.924  -6.062  5.361   1.00 51.28 ? 37  ASP   A OD1  1 
ATOM   493   O  OD2  . ASP   A 1 38  ? 26.776  -5.983  5.792   1.00 49.74 ? 37  ASP   A OD2  1 
ATOM   494   H  H    . ASP   A 1 38  ? 25.253  -9.524  3.977   1.00 37.69 ? 37  ASP   A H    1 
ATOM   495   H  HA   . ASP   A 1 38  ? 25.533  -7.479  4.455   1.00 36.54 ? 37  ASP   A HA   1 
ATOM   496   H  HB2  . ASP   A 1 38  ? 27.765  -8.507  4.718   1.00 40.15 ? 37  ASP   A HB2  1 
ATOM   497   H  HB3  . ASP   A 1 38  ? 28.149  -7.581  3.485   1.00 40.15 ? 37  ASP   A HB3  1 
ATOM   498   N  N    . GLY   A 1 39  ? 24.816  -6.969  1.841   1.00 22.93 ? 38  GLY   A N    1 
ATOM   499   C  CA   . GLY   A 1 39  ? 24.464  -6.112  0.720   1.00 26.59 ? 38  GLY   A CA   1 
ATOM   500   C  C    . GLY   A 1 39  ? 24.855  -6.656  -0.644  1.00 27.85 ? 38  GLY   A C    1 
ATOM   501   O  O    . GLY   A 1 39  ? 24.208  -6.325  -1.647  1.00 28.43 ? 38  GLY   A O    1 
ATOM   502   H  H    . GLY   A 1 39  ? 24.224  -7.571  2.003   1.00 27.51 ? 38  GLY   A H    1 
ATOM   503   H  HA2  . GLY   A 1 39  ? 23.504  -5.977  0.720   1.00 31.90 ? 38  GLY   A HA2  1 
ATOM   504   H  HA3  . GLY   A 1 39  ? 24.904  -5.255  0.834   1.00 31.90 ? 38  GLY   A HA3  1 
ATOM   505   N  N    . ALA   A 1 40  ? 25.893  -7.477  -0.710  1.00 25.53 ? 39  ALA   A N    1 
ATOM   506   C  CA   . ALA   A 1 40  ? 26.321  -8.008  -2.005  1.00 29.18 ? 39  ALA   A CA   1 
ATOM   507   C  C    . ALA   A 1 40  ? 25.367  -9.085  -2.487  1.00 29.29 ? 39  ALA   A C    1 
ATOM   508   O  O    . ALA   A 1 40  ? 24.929  -9.942  -1.714  1.00 27.30 ? 39  ALA   A O    1 
ATOM   509   C  CB   . ALA   A 1 40  ? 27.738  -8.566  -1.924  1.00 29.04 ? 39  ALA   A CB   1 
ATOM   510   H  H    . ALA   A 1 40  ? 26.360  -7.739  -0.037  1.00 30.63 ? 39  ALA   A H    1 
ATOM   511   H  HA   . ALA   A 1 40  ? 26.322  -7.286  -2.654  1.00 35.02 ? 39  ALA   A HA   1 
ATOM   512   H  HB1  . ALA   A 1 40  ? 28.066  -8.728  -2.822  1.00 34.85 ? 39  ALA   A HB1  1 
ATOM   513   H  HB2  . ALA   A 1 40  ? 28.307  -7.920  -1.476  1.00 34.85 ? 39  ALA   A HB2  1 
ATOM   514   H  HB3  . ALA   A 1 40  ? 27.722  -9.396  -1.422  1.00 34.85 ? 39  ALA   A HB3  1 
ATOM   515   N  N    . ASP   A 1 41  ? 25.065  -9.050  -3.787  1.00 29.97 ? 40  ASP   A N    1 
ATOM   516   C  CA   . ASP   A 1 41  ? 24.170  -10.013 -4.413  1.00 29.42 ? 40  ASP   A CA   1 
ATOM   517   C  C    . ASP   A 1 41  ? 24.942  -11.307 -4.677  1.00 32.21 ? 40  ASP   A C    1 
ATOM   518   O  O    . ASP   A 1 41  ? 25.810  -11.345 -5.557  1.00 30.56 ? 40  ASP   A O    1 
ATOM   519   C  CB   . ASP   A 1 41  ? 23.628  -9.423  -5.713  1.00 33.46 ? 40  ASP   A CB   1 
ATOM   520   C  CG   . ASP   A 1 41  ? 22.549  -10.265 -6.341  1.00 36.40 ? 40  ASP   A CG   1 
ATOM   521   O  OD1  . ASP   A 1 41  ? 22.412  -11.455 -5.996  1.00 33.41 ? 40  ASP   A OD1  1 
ATOM   522   O  OD2  . ASP   A 1 41  ? 21.850  -9.734  -7.221  1.00 40.42 ? 40  ASP   A OD2  1 
ATOM   523   H  H    . ASP   A 1 41  ? 25.375  -8.465  -4.336  1.00 35.96 ? 40  ASP   A H    1 
ATOM   524   H  HA   . ASP   A 1 41  ? 23.429  -10.217 -3.821  1.00 35.30 ? 40  ASP   A HA   1 
ATOM   525   H  HB2  . ASP   A 1 41  ? 23.253  -8.547  -5.529  1.00 40.15 ? 40  ASP   A HB2  1 
ATOM   526   H  HB3  . ASP   A 1 41  ? 24.355  -9.345  -6.351  1.00 40.15 ? 40  ASP   A HB3  1 
ATOM   527   N  N    . VAL   A 1 42  ? 24.602  -12.378 -3.963  1.00 28.81 ? 41  VAL   A N    1 
ATOM   528   C  CA   . VAL   A 1 42  ? 25.263  -13.676 -4.103  1.00 29.47 ? 41  VAL   A CA   1 
ATOM   529   C  C    . VAL   A 1 42  ? 24.333  -14.722 -4.730  1.00 31.35 ? 41  VAL   A C    1 
ATOM   530   O  O    . VAL   A 1 42  ? 24.594  -15.922 -4.653  1.00 30.48 ? 41  VAL   A O    1 
ATOM   531   C  CB   . VAL   A 1 42  ? 25.844  -14.159 -2.757  1.00 28.88 ? 41  VAL   A CB   1 
ATOM   532   C  CG1  . VAL   A 1 42  ? 26.767  -13.105 -2.170  1.00 29.83 ? 41  VAL   A CG1  1 
ATOM   533   C  CG2  . VAL   A 1 42  ? 24.689  -14.479 -1.763  1.00 29.39 ? 41  VAL   A CG2  1 
ATOM   534   H  H    . VAL   A 1 42  ? 23.975  -12.378 -3.374  1.00 34.57 ? 41  VAL   A H    1 
ATOM   535   H  HA   . VAL   A 1 42  ? 26.005  -13.563 -4.718  1.00 35.36 ? 41  VAL   A HA   1 
ATOM   536   H  HB   . VAL   A 1 42  ? 26.359  -14.967 -2.904  1.00 34.65 ? 41  VAL   A HB   1 
ATOM   537   H  HG11 . VAL   A 1 42  ? 27.475  -13.545 -1.674  1.00 35.80 ? 41  VAL   A HG11 1 
ATOM   538   H  HG12 . VAL   A 1 42  ? 27.147  -12.580 -2.892  1.00 35.80 ? 41  VAL   A HG12 1 
ATOM   539   H  HG13 . VAL   A 1 42  ? 26.256  -12.531 -1.578  1.00 35.80 ? 41  VAL   A HG13 1 
ATOM   540   H  HG21 . VAL   A 1 42  ? 25.070  -14.722 -0.904  1.00 35.27 ? 41  VAL   A HG21 1 
ATOM   541   H  HG22 . VAL   A 1 42  ? 24.129  -13.692 -1.665  1.00 35.27 ? 41  VAL   A HG22 1 
ATOM   542   H  HG23 . VAL   A 1 42  ? 24.166  -15.216 -2.114  1.00 35.27 ? 41  VAL   A HG23 1 
ATOM   543   N  N    . THR   A 1 43  ? 23.285  -14.279 -5.432  1.00 27.54 ? 42  THR   A N    1 
ATOM   544   C  CA   . THR   A 1 43  ? 22.321  -15.213 -6.004  1.00 32.81 ? 42  THR   A CA   1 
ATOM   545   C  C    . THR   A 1 43  ? 22.956  -16.172 -7.000  1.00 34.98 ? 42  THR   A C    1 
ATOM   546   O  O    . THR   A 1 43  ? 22.558  -17.342 -7.072  1.00 32.01 ? 42  THR   A O    1 
ATOM   547   C  CB   . THR   A 1 43  ? 21.192  -14.434 -6.691  1.00 38.64 ? 42  THR   A CB   1 
ATOM   548   O  OG1  . THR   A 1 43  ? 20.721  -13.403 -5.807  1.00 33.37 ? 42  THR   A OG1  1 
ATOM   549   C  CG2  . THR   A 1 43  ? 20.044  -15.346 -7.162  1.00 33.36 ? 42  THR   A CG2  1 
ATOM   550   H  H    . THR   A 1 43  ? 23.113  -13.450 -5.589  1.00 33.05 ? 42  THR   A H    1 
ATOM   551   H  HA   . THR   A 1 43  ? 21.955  -15.743 -5.278  1.00 39.37 ? 42  THR   A HA   1 
ATOM   552   H  HB   . THR   A 1 43  ? 21.535  -14.022 -7.499  1.00 46.37 ? 42  THR   A HB   1 
ATOM   553   H  HG1  . THR   A 1 43  ? 20.075  -12.997 -6.158  1.00 40.04 ? 42  THR   A HG1  1 
ATOM   554   H  HG21 . THR   A 1 43  ? 19.357  -14.817 -7.597  1.00 40.03 ? 42  THR   A HG21 1 
ATOM   555   H  HG22 . THR   A 1 43  ? 20.380  -16.004 -7.791  1.00 40.03 ? 42  THR   A HG22 1 
ATOM   556   H  HG23 . THR   A 1 43  ? 19.654  -15.807 -6.403  1.00 40.03 ? 42  THR   A HG23 1 
ATOM   557   N  N    . LYS   A 1 44  ? 23.989  -15.725 -7.703  1.00 36.01 ? 43  LYS   A N    1 
ATOM   558   C  CA   . LYS   A 1 44  ? 24.577  -16.457 -8.812  1.00 40.81 ? 43  LYS   A CA   1 
ATOM   559   C  C    . LYS   A 1 44  ? 25.815  -17.195 -8.362  1.00 45.74 ? 43  LYS   A C    1 
ATOM   560   O  O    . LYS   A 1 44  ? 26.515  -17.793 -9.178  1.00 51.10 ? 43  LYS   A O    1 
ATOM   561   C  CB   . LYS   A 1 44  ? 24.908  -15.517 -9.978  1.00 43.62 ? 43  LYS   A CB   1 
ATOM   562   C  CG   . LYS   A 1 44  ? 23.751  -14.596 -10.414 1.00 52.62 ? 43  LYS   A CG   1 
ATOM   563   C  CD   . LYS   A 1 44  ? 22.437  -15.348 -10.639 1.00 60.73 ? 43  LYS   A CD   1 
ATOM   564   C  CE   . LYS   A 1 44  ? 21.563  -14.621 -11.670 1.00 67.31 ? 43  LYS   A CE   1 
ATOM   565   N  NZ   . LYS   A 1 44  ? 21.959  -14.964 -13.071 1.00 71.93 ? 43  LYS   A NZ   1 
ATOM   566   H  H    . LYS   A 1 44  ? 24.380  -14.975 -7.550  1.00 43.21 ? 43  LYS   A H    1 
ATOM   567   H  HA   . LYS   A 1 44  ? 23.933  -17.095 -9.158  1.00 48.97 ? 43  LYS   A HA   1 
ATOM   568   H  HB2  . LYS   A 1 44  ? 25.649  -14.950 -9.716  1.00 52.35 ? 43  LYS   A HB2  1 
ATOM   569   H  HB3  . LYS   A 1 44  ? 25.157  -16.055 -10.746 1.00 52.35 ? 43  LYS   A HB3  1 
ATOM   570   H  HG2  . LYS   A 1 44  ? 23.600  -13.932 -9.723  1.00 63.14 ? 43  LYS   A HG2  1 
ATOM   571   H  HG3  . LYS   A 1 44  ? 23.991  -14.160 -11.246 1.00 63.14 ? 43  LYS   A HG3  1 
ATOM   572   H  HD2  . LYS   A 1 44  ? 22.627  -16.240 -10.970 1.00 72.87 ? 43  LYS   A HD2  1 
ATOM   573   H  HD3  . LYS   A 1 44  ? 21.947  -15.402 -9.803  1.00 72.87 ? 43  LYS   A HD3  1 
ATOM   574   H  HE2  . LYS   A 1 44  ? 20.636  -14.881 -11.544 1.00 80.77 ? 43  LYS   A HE2  1 
ATOM   575   H  HE3  . LYS   A 1 44  ? 21.658  -13.663 -11.553 1.00 80.77 ? 43  LYS   A HE3  1 
ATOM   576   H  HZ1  . LYS   A 1 44  ? 21.830  -15.832 -13.220 1.00 86.32 ? 43  LYS   A HZ1  1 
ATOM   577   H  HZ2  . LYS   A 1 44  ? 21.469  -14.496 -13.648 1.00 86.32 ? 43  LYS   A HZ2  1 
ATOM   578   H  HZ3  . LYS   A 1 44  ? 22.818  -14.773 -13.199 1.00 86.32 ? 43  LYS   A HZ3  1 
ATOM   579   N  N    . ILE   A 1 45  ? 26.112  -17.125 -7.063  1.00 35.95 ? 44  ILE   A N    1 
ATOM   580   C  CA   . ILE   A 1 45  ? 27.314  -17.679 -6.470  1.00 30.08 ? 44  ILE   A CA   1 
ATOM   581   C  C    . ILE   A 1 45  ? 26.996  -18.961 -5.715  1.00 34.37 ? 44  ILE   A C    1 
ATOM   582   O  O    . ILE   A 1 45  ? 25.920  -19.098 -5.122  1.00 36.77 ? 44  ILE   A O    1 
ATOM   583   C  CB   . ILE   A 1 45  ? 27.940  -16.617 -5.547  1.00 46.28 ? 44  ILE   A CB   1 
ATOM   584   C  CG1  . ILE   A 1 45  ? 29.039  -15.871 -6.282  1.00 46.18 ? 44  ILE   A CG1  1 
ATOM   585   C  CG2  . ILE   A 1 45  ? 28.532  -17.220 -4.287  1.00 41.02 ? 44  ILE   A CG2  1 
ATOM   586   C  CD1  . ILE   A 1 45  ? 28.549  -15.083 -7.441  1.00 53.02 ? 44  ILE   A CD1  1 
ATOM   587   H  H    . ILE   A 1 45  ? 25.604  -16.742 -6.485  1.00 43.14 ? 44  ILE   A H    1 
ATOM   588   H  HA   . ILE   A 1 45  ? 27.941  -17.935 -7.164  1.00 36.09 ? 44  ILE   A HA   1 
ATOM   589   H  HB   . ILE   A 1 45  ? 27.222  -16.016 -5.294  1.00 55.54 ? 44  ILE   A HB   1 
ATOM   590   H  HG12 . ILE   A 1 45  ? 29.467  -15.257 -5.665  1.00 55.41 ? 44  ILE   A HG12 1 
ATOM   591   H  HG13 . ILE   A 1 45  ? 29.686  -16.514 -6.612  1.00 55.41 ? 44  ILE   A HG13 1 
ATOM   592   H  HG21 . ILE   A 1 45  ? 29.310  -16.703 -4.025  1.00 49.23 ? 44  ILE   A HG21 1 
ATOM   593   H  HG22 . ILE   A 1 45  ? 27.866  -17.196 -3.582  1.00 49.23 ? 44  ILE   A HG22 1 
ATOM   594   H  HG23 . ILE   A 1 45  ? 28.791  -18.137 -4.467  1.00 49.23 ? 44  ILE   A HG23 1 
ATOM   595   H  HD11 . ILE   A 1 45  ? 28.337  -14.184 -7.144  1.00 63.62 ? 44  ILE   A HD11 1 
ATOM   596   H  HD12 . ILE   A 1 45  ? 29.243  -15.053 -8.118  1.00 63.62 ? 44  ILE   A HD12 1 
ATOM   597   H  HD13 . ILE   A 1 45  ? 27.755  -15.509 -7.799  1.00 63.62 ? 44  ILE   A HD13 1 
ATOM   598   N  N    . LYS   A 1 46  ? 28.008  -19.903 -5.684  1.00 35.99 ? 45  LYS   A N    1 
ATOM   599   C  CA   . LYS   A 1 46  ? 27.918  -21.120 -4.903  1.00 36.10 ? 45  LYS   A CA   1 
ATOM   600   C  C    . LYS   A 1 46  ? 28.463  -20.880 -3.497  1.00 31.52 ? 45  LYS   A C    1 
ATOM   601   O  O    . LYS   A 1 46  ? 29.365  -20.056 -3.296  1.00 37.25 ? 45  LYS   A O    1 
ATOM   602   C  CB   . LYS   A 1 46  ? 28.720  -22.229 -5.571  1.00 36.25 ? 45  LYS   A CB   1 
ATOM   603   C  CG   . LYS   A 1 46  ? 28.176  -22.620 -6.947  1.00 39.86 ? 45  LYS   A CG   1 
ATOM   604   C  CD   . LYS   A 1 46  ? 28.492  -24.060 -7.324  1.00 42.74 ? 45  LYS   A CD   1 
ATOM   605   C  CE   . LYS   A 1 46  ? 27.928  -24.388 -8.710  1.00 52.39 ? 45  LYS   A CE   1 
ATOM   606   N  NZ   . LYS   A 1 46  ? 28.710  -25.478 -9.367  1.00 53.65 ? 45  LYS   A NZ   1 
ATOM   607   H  H    . LYS   A 1 46  ? 28.746  -19.831 -6.120  1.00 43.19 ? 45  LYS   A H    1 
ATOM   608   H  HA   . LYS   A 1 46  ? 26.994  -21.406 -4.835  1.00 43.32 ? 45  LYS   A HA   1 
ATOM   609   H  HB2  . LYS   A 1 46  ? 29.636  -21.930 -5.686  1.00 43.49 ? 45  LYS   A HB2  1 
ATOM   610   H  HB3  . LYS   A 1 46  ? 28.698  -23.018 -5.006  1.00 43.49 ? 45  LYS   A HB3  1 
ATOM   611   H  HG2  . LYS   A 1 46  ? 27.211  -22.517 -6.946  1.00 47.84 ? 45  LYS   A HG2  1 
ATOM   612   H  HG3  . LYS   A 1 46  ? 28.571  -22.042 -7.619  1.00 47.84 ? 45  LYS   A HG3  1 
ATOM   613   H  HD2  . LYS   A 1 46  ? 29.454  -24.187 -7.344  1.00 51.29 ? 45  LYS   A HD2  1 
ATOM   614   H  HD3  . LYS   A 1 46  ? 28.092  -24.661 -6.676  1.00 51.29 ? 45  LYS   A HD3  1 
ATOM   615   H  HE2  . LYS   A 1 46  ? 27.007  -24.682 -8.622  1.00 62.87 ? 45  LYS   A HE2  1 
ATOM   616   H  HE3  . LYS   A 1 46  ? 27.971  -23.598 -9.271  1.00 62.87 ? 45  LYS   A HE3  1 
ATOM   617   H  HZ1  . LYS   A 1 46  ? 28.650  -26.226 -8.890  1.00 64.39 ? 45  LYS   A HZ1  1 
ATOM   618   H  HZ2  . LYS   A 1 46  ? 28.392  -25.630 -10.185 1.00 64.39 ? 45  LYS   A HZ2  1 
ATOM   619   H  HZ3  . LYS   A 1 46  ? 29.566  -25.243 -9.430  1.00 64.39 ? 45  LYS   A HZ3  1 
ATOM   620   N  N    . PRO   A 1 47  ? 27.957  -21.598 -2.509  1.00 26.85 ? 46  PRO   A N    1 
ATOM   621   C  CA   . PRO   A 1 47  ? 28.476  -21.435 -1.147  1.00 29.30 ? 46  PRO   A CA   1 
ATOM   622   C  C    . PRO   A 1 47  ? 29.992  -21.621 -1.101  1.00 39.48 ? 46  PRO   A C    1 
ATOM   623   O  O    . PRO   A 1 47  ? 30.549  -22.477 -1.790  1.00 32.67 ? 46  PRO   A O    1 
ATOM   624   C  CB   . PRO   A 1 47  ? 27.742  -22.525 -0.369  1.00 28.62 ? 46  PRO   A CB   1 
ATOM   625   C  CG   . PRO   A 1 47  ? 26.403  -22.636 -1.104  1.00 31.25 ? 46  PRO   A CG   1 
ATOM   626   C  CD   . PRO   A 1 47  ? 26.760  -22.466 -2.554  1.00 29.74 ? 46  PRO   A CD   1 
ATOM   627   H  HA   . PRO   A 1 47  ? 28.249  -20.563 -0.789  1.00 35.16 ? 46  PRO   A HA   1 
ATOM   628   H  HB2  . PRO   A 1 47  ? 28.236  -23.359 -0.407  1.00 34.34 ? 46  PRO   A HB2  1 
ATOM   629   H  HB3  . PRO   A 1 47  ? 27.617  -22.255 0.554   1.00 34.34 ? 46  PRO   A HB3  1 
ATOM   630   H  HG2  . PRO   A 1 47  ? 26.005  -23.506 -0.943  1.00 37.50 ? 46  PRO   A HG2  1 
ATOM   631   H  HG3  . PRO   A 1 47  ? 25.801  -21.936 -0.808  1.00 37.50 ? 46  PRO   A HG3  1 
ATOM   632   H  HD2  . PRO   A 1 47  ? 26.968  -23.322 -2.961  1.00 35.69 ? 46  PRO   A HD2  1 
ATOM   633   H  HD3  . PRO   A 1 47  ? 26.039  -22.035 -3.039  1.00 35.69 ? 46  PRO   A HD3  1 
ATOM   634   N  N    . HIS   A 1 48  ? 30.661  -20.806 -0.280  1.00 36.02 ? 47  HIS   A N    1 
ATOM   635   C  CA   . HIS   A 1 48  ? 32.083  -20.944 -0.003  1.00 33.79 ? 47  HIS   A CA   1 
ATOM   636   C  C    . HIS   A 1 48  ? 32.228  -21.464 1.424   1.00 36.26 ? 47  HIS   A C    1 
ATOM   637   O  O    . HIS   A 1 48  ? 31.348  -21.258 2.265   1.00 32.13 ? 47  HIS   A O    1 
ATOM   638   C  CB   . HIS   A 1 48  ? 32.827  -19.609 -0.155  1.00 38.48 ? 47  HIS   A CB   1 
ATOM   639   C  CG   . HIS   A 1 48  ? 34.317  -19.734 -0.015  1.00 51.17 ? 47  HIS   A CG   1 
ATOM   640   N  ND1  . HIS   A 1 48  ? 35.061  -18.950 0.842   1.00 52.45 ? 47  HIS   A ND1  1 
ATOM   641   C  CD2  . HIS   A 1 48  ? 35.203  -20.547 -0.641  1.00 58.08 ? 47  HIS   A CD2  1 
ATOM   642   C  CE1  . HIS   A 1 48  ? 36.335  -19.288 0.754   1.00 49.24 ? 47  HIS   A CE1  1 
ATOM   643   N  NE2  . HIS   A 1 48  ? 36.449  -20.252 -0.141  1.00 57.03 ? 47  HIS   A NE2  1 
ATOM   644   H  H    . HIS   A 1 48  ? 30.297  -20.147 0.136   1.00 43.22 ? 47  HIS   A H    1 
ATOM   645   H  HA   . HIS   A 1 48  ? 32.492  -21.564 -0.627  1.00 40.55 ? 47  HIS   A HA   1 
ATOM   646   H  HB2  . HIS   A 1 48  ? 32.640  -19.245 -1.034  1.00 46.17 ? 47  HIS   A HB2  1 
ATOM   647   H  HB3  . HIS   A 1 48  ? 32.514  -18.997 0.530   1.00 46.17 ? 47  HIS   A HB3  1 
ATOM   648   H  HD1  . HIS   A 1 48  ? 34.744  -18.337 1.354   1.00 62.93 ? 47  HIS   A HD1  1 
ATOM   649   H  HD2  . HIS   A 1 48  ? 35.004  -21.184 -1.289  1.00 69.70 ? 47  HIS   A HD2  1 
ATOM   650   H  HE1  . HIS   A 1 48  ? 37.033  -18.910 1.239   1.00 59.09 ? 47  HIS   A HE1  1 
ATOM   651   N  N    . ASN   A 1 49  ? 33.348  -22.136 1.709   1.00 32.11 ? 48  ASN   A N    1 
ATOM   652   C  CA   . ASN   A 1 49  ? 33.553  -22.649 3.059   1.00 36.91 ? 48  ASN   A CA   1 
ATOM   653   C  C    . ASN   A 1 49  ? 33.424  -21.529 4.085   1.00 31.58 ? 48  ASN   A C    1 
ATOM   654   O  O    . ASN   A 1 49  ? 32.931  -21.744 5.191   1.00 32.06 ? 48  ASN   A O    1 
ATOM   655   C  CB   . ASN   A 1 49  ? 34.928  -23.316 3.230   1.00 39.77 ? 48  ASN   A CB   1 
ATOM   656   C  CG   . ASN   A 1 49  ? 35.056  -24.616 2.456   1.00 49.24 ? 48  ASN   A CG   1 
ATOM   657   O  OD1  . ASN   A 1 49  ? 34.099  -25.390 2.338   1.00 46.79 ? 48  ASN   A OD1  1 
ATOM   658   N  ND2  . ASN   A 1 49  ? 36.273  -24.907 2.003   1.00 49.25 ? 48  ASN   A ND2  1 
ATOM   659   H  H    . ASN   A 1 49  ? 33.983  -22.303 1.154   1.00 38.53 ? 48  ASN   A H    1 
ATOM   660   H  HA   . ASN   A 1 49  ? 32.880  -23.331 3.210   1.00 44.29 ? 48  ASN   A HA   1 
ATOM   661   H  HB2  . ASN   A 1 49  ? 35.614  -22.709 2.911   1.00 47.73 ? 48  ASN   A HB2  1 
ATOM   662   H  HB3  . ASN   A 1 49  ? 35.069  -23.512 4.169   1.00 47.73 ? 48  ASN   A HB3  1 
ATOM   663   H  HD21 . ASN   A 1 49  ? 36.928  -24.371 2.156   1.00 59.11 ? 48  ASN   A HD21 1 
ATOM   664   H  HD22 . ASN   A 1 49  ? 36.405  -25.631 1.558   1.00 59.11 ? 48  ASN   A HD22 1 
ATOM   665   N  N    . SER   A 1 50  ? 33.884  -20.331 3.736   1.00 32.39 ? 49  SER   A N    1 
ATOM   666   C  CA   . SER   A 1 50  ? 33.895  -19.210 4.680   1.00 39.19 ? 49  SER   A CA   1 
ATOM   667   C  C    . SER   A 1 50  ? 32.503  -18.675 5.003   1.00 39.42 ? 49  SER   A C    1 
ATOM   668   O  O    . SER   A 1 50  ? 32.354  -17.880 5.945   1.00 33.46 ? 49  SER   A O    1 
ATOM   669   C  CB   . SER   A 1 50  ? 34.781  -18.104 4.106   1.00 39.10 ? 49  SER   A CB   1 
ATOM   670   O  OG   . SER   A 1 50  ? 34.189  -17.512 2.965   1.00 39.21 ? 49  SER   A OG   1 
ATOM   671   H  HA   . SER   A 1 50  ? 34.272  -19.501 5.525   1.00 47.03 ? 49  SER   A HA   1 
ATOM   672   H  HB2  . SER   A 1 50  ? 34.910  -17.421 4.783   1.00 46.92 ? 49  SER   A HB2  1 
ATOM   673   H  HB3  . SER   A 1 50  ? 35.636  -18.486 3.853   1.00 46.92 ? 49  SER   A HB3  1 
ATOM   674   N  N    . HIS   A 1 51  ? 31.477  -19.109 4.278   1.00 33.90 ? 50  HIS   A N    1 
ATOM   675   C  CA   . HIS   A 1 51  ? 30.119  -18.660 4.547   1.00 33.04 ? 50  HIS   A CA   1 
ATOM   676   C  C    . HIS   A 1 51  ? 29.474  -19.393 5.702   1.00 26.75 ? 50  HIS   A C    1 
ATOM   677   O  O    . HIS   A 1 51  ? 28.378  -19.011 6.117   1.00 30.35 ? 50  HIS   A O    1 
ATOM   678   C  CB   . HIS   A 1 51  ? 29.254  -18.856 3.308   1.00 25.52 ? 50  HIS   A CB   1 
ATOM   679   C  CG   . HIS   A 1 51  ? 29.648  -18.013 2.147   1.00 28.67 ? 50  HIS   A CG   1 
ATOM   680   N  ND1  . HIS   A 1 51  ? 29.230  -18.296 0.865   1.00 30.52 ? 50  HIS   A ND1  1 
ATOM   681   C  CD2  . HIS   A 1 51  ? 30.378  -16.877 2.066   1.00 30.28 ? 50  HIS   A CD2  1 
ATOM   682   C  CE1  . HIS   A 1 51  ? 29.716  -17.385 0.041   1.00 33.28 ? 50  HIS   A CE1  1 
ATOM   683   N  NE2  . HIS   A 1 51  ? 30.409  -16.509 0.748   1.00 33.69 ? 50  HIS   A NE2  1 
ATOM   684   H  H    . HIS   A 1 51  ? 31.543  -19.665 3.625   1.00 40.69 ? 50  HIS   A H    1 
ATOM   685   H  HA   . HIS   A 1 51  ? 30.149  -17.715 4.763   1.00 39.65 ? 50  HIS   A HA   1 
ATOM   686   H  HB2  . HIS   A 1 51  ? 29.315  -19.783 3.032   1.00 30.62 ? 50  HIS   A HB2  1 
ATOM   687   H  HB3  . HIS   A 1 51  ? 28.337  -18.635 3.533   1.00 30.62 ? 50  HIS   A HB3  1 
ATOM   688   H  HD2  . HIS   A 1 51  ? 30.782  -16.429 2.774   1.00 36.34 ? 50  HIS   A HD2  1 
ATOM   689   H  HE1  . HIS   A 1 51  ? 29.593  -17.364 -0.880  1.00 39.93 ? 50  HIS   A HE1  1 
ATOM   690   H  HE2  . HIS   A 1 51  ? 30.813  -15.819 0.431   1.00 40.43 ? 50  HIS   A HE2  1 
ATOM   691   N  N    . GLU   A 1 52  ? 30.117  -20.422 6.240   1.00 24.85 ? 51  GLU   A N    1 
ATOM   692   C  CA   . GLU   A 1 52  ? 29.490  -21.207 7.286   1.00 28.03 ? 51  GLU   A CA   1 
ATOM   693   C  C    . GLU   A 1 52  ? 29.181  -20.314 8.478   1.00 24.15 ? 51  GLU   A C    1 
ATOM   694   O  O    . GLU   A 1 52  ? 30.042  -19.569 8.946   1.00 28.60 ? 51  GLU   A O    1 
ATOM   695   C  CB   . GLU   A 1 52  ? 30.395  -22.356 7.727   1.00 27.47 ? 51  GLU   A CB   1 
ATOM   696   C  CG   . GLU   A 1 52  ? 29.836  -23.100 8.902   1.00 34.17 ? 51  GLU   A CG   1 
ATOM   697   C  CD   . GLU   A 1 52  ? 29.893  -24.604 8.693   1.00 53.01 ? 51  GLU   A CD   1 
ATOM   698   O  OE1  . GLU   A 1 52  ? 31.011  -25.147 8.528   1.00 54.43 ? 51  GLU   A OE1  1 
ATOM   699   O  OE2  . GLU   A 1 52  ? 28.815  -25.238 8.660   1.00 55.23 ? 51  GLU   A OE2  1 
ATOM   700   H  H    . GLU   A 1 52  ? 30.906  -20.681 6.019   1.00 29.82 ? 51  GLU   A H    1 
ATOM   701   H  HA   . GLU   A 1 52  ? 28.669  -21.593 6.943   1.00 33.64 ? 51  GLU   A HA   1 
ATOM   702   H  HB2  . GLU   A 1 52  ? 30.495  -22.982 6.992   1.00 32.96 ? 51  GLU   A HB2  1 
ATOM   703   H  HB3  . GLU   A 1 52  ? 31.261  -21.999 7.979   1.00 32.96 ? 51  GLU   A HB3  1 
ATOM   704   H  HG2  . GLU   A 1 52  ? 30.352  -22.883 9.694   1.00 41.01 ? 51  GLU   A HG2  1 
ATOM   705   H  HG3  . GLU   A 1 52  ? 28.908  -22.846 9.030   1.00 41.01 ? 51  GLU   A HG3  1 
ATOM   706   N  N    . GLY   A 1 53  ? 27.941  -20.361 8.934   1.00 26.75 ? 52  GLY   A N    1 
ATOM   707   C  CA   . GLY   A 1 53  ? 27.542  -19.600 10.101  1.00 27.22 ? 52  GLY   A CA   1 
ATOM   708   C  C    . GLY   A 1 53  ? 27.156  -18.158 9.827   1.00 28.94 ? 52  GLY   A C    1 
ATOM   709   O  O    . GLY   A 1 53  ? 26.741  -17.466 10.763  1.00 24.78 ? 52  GLY   A O    1 
ATOM   710   H  H    . GLY   A 1 53  ? 27.310  -20.828 8.582   1.00 32.10 ? 52  GLY   A H    1 
ATOM   711   H  HA2  . GLY   A 1 53  ? 26.779  -20.038 10.510  1.00 32.67 ? 52  GLY   A HA2  1 
ATOM   712   H  HA3  . GLY   A 1 53  ? 28.278  -19.593 10.733  1.00 32.67 ? 52  GLY   A HA3  1 
ATOM   713   N  N    . LYS   A 1 54  ? 27.286  -17.683 8.591   1.00 23.37 ? 53  LYS   A N    1 
ATOM   714   C  CA   . LYS   A 1 54  ? 27.000  -16.289 8.279   1.00 24.41 ? 53  LYS   A CA   1 
ATOM   715   C  C    . LYS   A 1 54  ? 25.513  -16.094 8.011   1.00 26.43 ? 53  LYS   A C    1 
ATOM   716   O  O    . LYS   A 1 54  ? 24.743  -17.043 7.803   1.00 21.67 ? 53  LYS   A O    1 
ATOM   717   C  CB   . LYS   A 1 54  ? 27.820  -15.800 7.084   1.00 22.72 ? 53  LYS   A CB   1 
ATOM   718   C  CG   . LYS   A 1 54  ? 29.342  -15.629 7.320   1.00 26.25 ? 53  LYS   A CG   1 
ATOM   719   C  CD   . LYS   A 1 54  ? 29.965  -14.722 6.235   1.00 34.16 ? 53  LYS   A CD   1 
ATOM   720   C  CE   . LYS   A 1 54  ? 31.454  -14.407 6.488   1.00 38.07 ? 53  LYS   A CE   1 
ATOM   721   N  NZ   . LYS   A 1 54  ? 31.914  -14.940 7.785   1.00 46.96 ? 53  LYS   A NZ   1 
ATOM   722   H  H    . LYS   A 1 54  ? 27.539  -18.150 7.915   1.00 28.04 ? 53  LYS   A H    1 
ATOM   723   H  HA   . LYS   A 1 54  ? 27.250  -15.744 9.041   1.00 29.29 ? 53  LYS   A HA   1 
ATOM   724   H  HB2  . LYS   A 1 54  ? 27.713  -16.438 6.362   1.00 27.26 ? 53  LYS   A HB2  1 
ATOM   725   H  HB3  . LYS   A 1 54  ? 27.474  -14.934 6.815   1.00 27.26 ? 53  LYS   A HB3  1 
ATOM   726   H  HG2  . LYS   A 1 54  ? 29.492  -15.220 8.187   1.00 31.50 ? 53  LYS   A HG2  1 
ATOM   727   H  HG3  . LYS   A 1 54  ? 29.775  -16.496 7.283   1.00 31.50 ? 53  LYS   A HG3  1 
ATOM   728   H  HD2  . LYS   A 1 54  ? 29.896  -15.166 5.376   1.00 40.99 ? 53  LYS   A HD2  1 
ATOM   729   H  HD3  . LYS   A 1 54  ? 29.482  -13.881 6.213   1.00 40.99 ? 53  LYS   A HD3  1 
ATOM   730   H  HE2  . LYS   A 1 54  ? 31.990  -14.811 5.787   1.00 45.68 ? 53  LYS   A HE2  1 
ATOM   731   H  HE3  . LYS   A 1 54  ? 31.582  -13.446 6.491   1.00 45.68 ? 53  LYS   A HE3  1 
ATOM   732   H  HZ1  . LYS   A 1 54  ? 32.742  -14.659 7.953   1.00 56.36 ? 53  LYS   A HZ1  1 
ATOM   733   H  HZ2  . LYS   A 1 54  ? 31.376  -14.660 8.437   1.00 56.36 ? 53  LYS   A HZ2  1 
ATOM   734   H  HZ3  . LYS   A 1 54  ? 31.909  -15.829 7.768   1.00 56.36 ? 53  LYS   A HZ3  1 
ATOM   735   N  N    . THR   A 1 55  ? 25.097  -14.831 8.050   1.00 22.83 ? 54  THR   A N    1 
ATOM   736   C  CA   . THR   A 1 55  ? 23.701  -14.478 7.901   1.00 21.46 ? 54  THR   A CA   1 
ATOM   737   C  C    . THR   A 1 55  ? 23.500  -13.873 6.529   1.00 21.71 ? 54  THR   A C    1 
ATOM   738   O  O    . THR   A 1 55  ? 24.251  -12.968 6.128   1.00 23.42 ? 54  THR   A O    1 
ATOM   739   C  CB   . THR   A 1 55  ? 23.244  -13.480 8.969   1.00 22.67 ? 54  THR   A CB   1 
ATOM   740   O  OG1  . THR   A 1 55  ? 23.277  -14.091 10.253  1.00 22.35 ? 54  THR   A OG1  1 
ATOM   741   C  CG2  . THR   A 1 55  ? 21.836  -13.050 8.656   1.00 20.33 ? 54  THR   A CG2  1 
ATOM   742   H  H    . THR   A 1 55  ? 25.617  -14.156 8.163   1.00 27.39 ? 54  THR   A H    1 
ATOM   743   H  HA   . THR   A 1 55  ? 23.159  -15.278 7.990   1.00 25.75 ? 54  THR   A HA   1 
ATOM   744   H  HB   . THR   A 1 55  ? 23.829  -12.706 8.982   1.00 27.20 ? 54  THR   A HB   1 
ATOM   745   H  HG1  . THR   A 1 55  ? 22.541  -14.462 10.414  1.00 26.82 ? 54  THR   A HG1  1 
ATOM   746   H  HG21 . THR   A 1 55  ? 21.411  -12.698 9.454   1.00 24.39 ? 54  THR   A HG21 1 
ATOM   747   H  HG22 . THR   A 1 55  ? 21.844  -12.360 7.974   1.00 24.39 ? 54  THR   A HG22 1 
ATOM   748   H  HG23 . THR   A 1 55  ? 21.322  -13.806 8.333   1.00 24.39 ? 54  THR   A HG23 1 
ATOM   749   N  N    . PHE   A 1 56  ? 22.482  -14.359 5.824   1.00 21.55 ? 55  PHE   A N    1 
ATOM   750   C  CA   . PHE   A 1 56  ? 22.169  -13.907 4.477   1.00 19.09 ? 55  PHE   A CA   1 
ATOM   751   C  C    . PHE   A 1 56  ? 20.761  -13.328 4.440   1.00 21.23 ? 55  PHE   A C    1 
ATOM   752   O  O    . PHE   A 1 56  ? 19.828  -13.936 4.958   1.00 21.82 ? 55  PHE   A O    1 
ATOM   753   C  CB   . PHE   A 1 56  ? 22.251  -15.073 3.440   1.00 23.17 ? 55  PHE   A CB   1 
ATOM   754   C  CG   . PHE   A 1 56  ? 23.634  -15.617 3.255   1.00 21.64 ? 55  PHE   A CG   1 
ATOM   755   C  CD1  . PHE   A 1 56  ? 24.184  -16.451 4.198   1.00 18.37 ? 55  PHE   A CD1  1 
ATOM   756   C  CD2  . PHE   A 1 56  ? 24.387  -15.282 2.145   1.00 23.66 ? 55  PHE   A CD2  1 
ATOM   757   C  CE1  . PHE   A 1 56  ? 25.458  -16.960 4.051   1.00 22.91 ? 55  PHE   A CE1  1 
ATOM   758   C  CE2  . PHE   A 1 56  ? 25.667  -15.777 1.987   1.00 26.42 ? 55  PHE   A CE2  1 
ATOM   759   C  CZ   . PHE   A 1 56  ? 26.204  -16.619 2.941   1.00 25.15 ? 55  PHE   A CZ   1 
ATOM   760   H  H    . PHE   A 1 56  ? 21.947  -14.966 6.114   1.00 25.86 ? 55  PHE   A H    1 
ATOM   761   H  HA   . PHE   A 1 56  ? 22.807  -13.221 4.227   1.00 22.91 ? 55  PHE   A HA   1 
ATOM   762   H  HB2  . PHE   A 1 56  ? 21.684  -15.800 3.742   1.00 27.80 ? 55  PHE   A HB2  1 
ATOM   763   H  HB3  . PHE   A 1 56  ? 21.942  -14.748 2.579   1.00 27.80 ? 55  PHE   A HB3  1 
ATOM   764   H  HD1  . PHE   A 1 56  ? 23.688  -16.678 4.951   1.00 22.05 ? 55  PHE   A HD1  1 
ATOM   765   H  HD2  . PHE   A 1 56  ? 24.028  -14.718 1.498   1.00 28.39 ? 55  PHE   A HD2  1 
ATOM   766   H  HE1  . PHE   A 1 56  ? 25.812  -17.529 4.696   1.00 27.49 ? 55  PHE   A HE1  1 
ATOM   767   H  HE2  . PHE   A 1 56  ? 26.167  -15.543 1.239   1.00 31.71 ? 55  PHE   A HE2  1 
ATOM   768   H  HZ   . PHE   A 1 56  ? 27.065  -16.954 2.836   1.00 30.18 ? 55  PHE   A HZ   1 
ATOM   769   N  N    . TYR   A 1 57  ? 20.582  -12.204 3.736   1.00 20.98 ? 56  TYR   A N    1 
ATOM   770   C  CA   . TYR   A 1 57  ? 19.236  -11.708 3.473   1.00 19.74 ? 56  TYR   A CA   1 
ATOM   771   C  C    . TYR   A 1 57  ? 18.625  -12.408 2.255   1.00 22.91 ? 56  TYR   A C    1 
ATOM   772   O  O    . TYR   A 1 57  ? 19.292  -12.627 1.240   1.00 24.77 ? 56  TYR   A O    1 
ATOM   773   C  CB   . TYR   A 1 57  ? 19.248  -10.200 3.212   1.00 25.98 ? 56  TYR   A CB   1 
ATOM   774   C  CG   . TYR   A 1 57  ? 19.348  -9.328  4.434   1.00 24.01 ? 56  TYR   A CG   1 
ATOM   775   C  CD1  . TYR   A 1 57  ? 20.535  -9.202  5.110   1.00 22.79 ? 56  TYR   A CD1  1 
ATOM   776   C  CD2  . TYR   A 1 57  ? 18.266  -8.586  4.863   1.00 26.99 ? 56  TYR   A CD2  1 
ATOM   777   C  CE1  . TYR   A 1 57  ? 20.628  -8.388  6.216   1.00 24.34 ? 56  TYR   A CE1  1 
ATOM   778   C  CE2  . TYR   A 1 57  ? 18.352  -7.781  5.971   1.00 22.19 ? 56  TYR   A CE2  1 
ATOM   779   C  CZ   . TYR   A 1 57  ? 19.527  -7.682  6.632   1.00 23.30 ? 56  TYR   A CZ   1 
ATOM   780   O  OH   . TYR   A 1 57  ? 19.616  -6.856  7.728   1.00 25.92 ? 56  TYR   A OH   1 
ATOM   781   H  H    . TYR   A 1 57  ? 21.215  -11.722 3.408   1.00 25.17 ? 56  TYR   A H    1 
ATOM   782   H  HA   . TYR   A 1 57  ? 18.688  -11.889 4.252   1.00 23.68 ? 56  TYR   A HA   1 
ATOM   783   H  HB2  . TYR   A 1 57  ? 20.011  -9.994  2.649   1.00 31.18 ? 56  TYR   A HB2  1 
ATOM   784   H  HB3  . TYR   A 1 57  ? 18.426  -9.963  2.756   1.00 31.18 ? 56  TYR   A HB3  1 
ATOM   785   H  HD1  . TYR   A 1 57  ? 21.283  -9.672  4.819   1.00 27.35 ? 56  TYR   A HD1  1 
ATOM   786   H  HD2  . TYR   A 1 57  ? 17.465  -8.633  4.394   1.00 32.38 ? 56  TYR   A HD2  1 
ATOM   787   H  HE1  . TYR   A 1 57  ? 21.432  -8.316  6.677   1.00 29.21 ? 56  TYR   A HE1  1 
ATOM   788   H  HE2  . TYR   A 1 57  ? 17.608  -7.307  6.265   1.00 26.62 ? 56  TYR   A HE2  1 
ATOM   789   H  HH   . TYR   A 1 57  ? 20.348  -6.977  8.121   1.00 31.10 ? 56  TYR   A HH   1 
ATOM   790   N  N    . VAL   A 1 58  ? 17.334  -12.721 2.352   1.00 22.16 ? 57  VAL   A N    1 
ATOM   791   C  CA   . VAL   A 1 58  ? 16.570  -13.340 1.276   1.00 24.98 ? 57  VAL   A CA   1 
ATOM   792   C  C    . VAL   A 1 58  ? 15.311  -12.511 1.097   1.00 31.45 ? 57  VAL   A C    1 
ATOM   793   O  O    . VAL   A 1 58  ? 14.959  -11.693 1.942   1.00 30.02 ? 57  VAL   A O    1 
ATOM   794   C  CB   . VAL   A 1 58  ? 16.197  -14.816 1.552   1.00 25.39 ? 57  VAL   A CB   1 
ATOM   795   C  CG1  . VAL   A 1 58  ? 17.453  -15.688 1.512   1.00 27.66 ? 57  VAL   A CG1  1 
ATOM   796   C  CG2  . VAL   A 1 58  ? 15.417  -14.916 2.880   1.00 27.74 ? 57  VAL   A CG2  1 
ATOM   797   H  H    . VAL   A 1 58  ? 16.864  -12.579 3.058   1.00 26.59 ? 57  VAL   A H    1 
ATOM   798   H  HA   . VAL   A 1 58  ? 17.097  -13.331 0.462   1.00 29.98 ? 57  VAL   A HA   1 
ATOM   799   H  HB   . VAL   A 1 58  ? 15.608  -15.159 0.862   1.00 30.47 ? 57  VAL   A HB   1 
ATOM   800   H  HG11 . VAL   A 1 58  ? 17.191  -16.614 1.390   1.00 33.19 ? 57  VAL   A HG11 1 
ATOM   801   H  HG12 . VAL   A 1 58  ? 18.013  -15.402 0.773   1.00 33.19 ? 57  VAL   A HG12 1 
ATOM   802   H  HG13 . VAL   A 1 58  ? 17.934  -15.588 2.349   1.00 33.19 ? 57  VAL   A HG13 1 
ATOM   803   H  HG21 . VAL   A 1 58  ? 15.251  -15.851 3.078   1.00 33.29 ? 57  VAL   A HG21 1 
ATOM   804   H  HG22 . VAL   A 1 58  ? 15.947  -14.517 3.588   1.00 33.29 ? 57  VAL   A HG22 1 
ATOM   805   H  HG23 . VAL   A 1 58  ? 14.576  -14.442 2.789   1.00 33.29 ? 57  VAL   A HG23 1 
ATOM   806   N  N    . LEU   A 1 59  ? 14.690  -12.655 -0.057  1.00 25.94 ? 58  LEU   A N    1 
ATOM   807   C  CA   . LEU   A 1 59  ? 13.404  -12.013 -0.284  1.00 30.78 ? 58  LEU   A CA   1 
ATOM   808   C  C    . LEU   A 1 59  ? 12.294  -12.765 0.452   1.00 38.21 ? 58  LEU   A C    1 
ATOM   809   O  O    . LEU   A 1 59  ? 12.331  -13.997 0.548   1.00 38.91 ? 58  LEU   A O    1 
ATOM   810   C  CB   . LEU   A 1 59  ? 13.125  -11.970 -1.781  1.00 32.23 ? 58  LEU   A CB   1 
ATOM   811   C  CG   . LEU   A 1 59  ? 14.176  -11.176 -2.527  1.00 35.27 ? 58  LEU   A CG   1 
ATOM   812   C  CD1  . LEU   A 1 59  ? 13.745  -10.958 -3.987  1.00 35.66 ? 58  LEU   A CD1  1 
ATOM   813   C  CD2  . LEU   A 1 59  ? 14.465  -9.812  -1.847  1.00 36.48 ? 58  LEU   A CD2  1 
ATOM   814   H  H    . LEU   A 1 59  ? 14.986  -13.113 -0.723  1.00 31.13 ? 58  LEU   A H    1 
ATOM   815   H  HA   . LEU   A 1 59  ? 13.411  -11.106 0.060   1.00 36.94 ? 58  LEU   A HA   1 
ATOM   816   H  HB2  . LEU   A 1 59  ? 13.122  -12.874 -2.131  1.00 38.68 ? 58  LEU   A HB2  1 
ATOM   817   H  HB3  . LEU   A 1 59  ? 12.263  -11.552 -1.933  1.00 38.68 ? 58  LEU   A HB3  1 
ATOM   818   H  HG   . LEU   A 1 59  ? 15.002  -11.685 -2.513  1.00 42.32 ? 58  LEU   A HG   1 
ATOM   819   H  HD11 . LEU   A 1 59  ? 14.488  -10.580 -4.483  1.00 42.79 ? 58  LEU   A HD11 1 
ATOM   820   H  HD12 . LEU   A 1 59  ? 13.492  -11.812 -4.372  1.00 42.79 ? 58  LEU   A HD12 1 
ATOM   821   H  HD13 . LEU   A 1 59  ? 12.991  -10.349 -4.006  1.00 42.79 ? 58  LEU   A HD13 1 
ATOM   822   H  HD21 . LEU   A 1 59  ? 14.857  -9.211  -2.500  1.00 43.77 ? 58  LEU   A HD21 1 
ATOM   823   H  HD22 . LEU   A 1 59  ? 13.632  -9.442  -1.515  1.00 43.77 ? 58  LEU   A HD22 1 
ATOM   824   H  HD23 . LEU   A 1 59  ? 15.082  -9.950  -1.112  1.00 43.77 ? 58  LEU   A HD23 1 
ATOM   825   N  N    . PRO   A 1 60  ? 11.292  -12.059 0.992   1.00 36.40 ? 59  PRO   A N    1 
ATOM   826   C  CA   . PRO   A 1 60  ? 10.182  -12.771 1.640   1.00 43.43 ? 59  PRO   A CA   1 
ATOM   827   C  C    . PRO   A 1 60  ? 9.391   -13.587 0.628   1.00 48.03 ? 59  PRO   A C    1 
ATOM   828   O  O    . PRO   A 1 60  ? 8.637   -13.045 -0.182  1.00 54.89 ? 59  PRO   A O    1 
ATOM   829   C  CB   . PRO   A 1 60  ? 9.373   -11.640 2.293   1.00 43.79 ? 59  PRO   A CB   1 
ATOM   830   C  CG   . PRO   A 1 60  ? 9.723   -10.419 1.540   1.00 41.62 ? 59  PRO   A CG   1 
ATOM   831   C  CD   . PRO   A 1 60  ? 11.163  -10.595 1.124   1.00 41.23 ? 59  PRO   A CD   1 
ATOM   832   H  HA   . PRO   A 1 60  ? 10.486  -13.358 2.350   1.00 52.12 ? 59  PRO   A HA   1 
ATOM   833   H  HB2  . PRO   A 1 60  ? 8.424   -11.831 2.219   1.00 52.54 ? 59  PRO   A HB2  1 
ATOM   834   H  HB3  . PRO   A 1 60  ? 9.623   -11.554 3.226   1.00 52.54 ? 59  PRO   A HB3  1 
ATOM   835   H  HG2  . PRO   A 1 60  ? 9.148   -10.337 0.763   1.00 49.94 ? 59  PRO   A HG2  1 
ATOM   836   H  HG3  . PRO   A 1 60  ? 9.623   -9.641  2.111   1.00 49.94 ? 59  PRO   A HG3  1 
ATOM   837   H  HD2  . PRO   A 1 60  ? 11.335  -10.154 0.277   1.00 49.48 ? 59  PRO   A HD2  1 
ATOM   838   H  HD3  . PRO   A 1 60  ? 11.764  -10.254 1.804   1.00 49.48 ? 59  PRO   A HD3  1 
ATOM   839   N  N    . ASN   A 1 61  ? 9.560   -14.908 0.687   1.00 49.07 ? 60  ASN   A N    1 
ATOM   840   C  CA   . ASN   A 1 61  ? 8.975   -15.837 -0.272  1.00 51.25 ? 60  ASN   A CA   1 
ATOM   841   C  C    . ASN   A 1 61  ? 7.959   -16.770 0.382   1.00 51.54 ? 60  ASN   A C    1 
ATOM   842   O  O    . ASN   A 1 61  ? 7.385   -17.619 -0.310  1.00 49.12 ? 60  ASN   A O    1 
ATOM   843   C  CB   . ASN   A 1 61  ? 10.120  -16.611 -0.961  1.00 51.31 ? 60  ASN   A CB   1 
ATOM   844   C  CG   . ASN   A 1 61  ? 10.618  -17.789 -0.141  1.00 59.02 ? 60  ASN   A CG   1 
ATOM   845   O  OD1  . ASN   A 1 61  ? 10.651  -17.734 1.087   1.00 60.87 ? 60  ASN   A OD1  1 
ATOM   846   N  ND2  . ASN   A 1 61  ? 11.142  -18.804 -0.825  1.00 63.70 ? 60  ASN   A ND2  1 
ATOM   847   H  H    . ASN   A 1 61  ? 10.025  -15.301 1.294   1.00 58.88 ? 60  ASN   A H    1 
ATOM   848   H  HA   . ASN   A 1 61  ? 8.493   -15.371 -0.973  1.00 61.50 ? 60  ASN   A HA   1 
ATOM   849   H  HB2  . ASN   A 1 61  ? 9.804   -16.951 -1.812  1.00 61.57 ? 60  ASN   A HB2  1 
ATOM   850   H  HB3  . ASN   A 1 61  ? 10.867  -16.008 -1.102  1.00 61.57 ? 60  ASN   A HB3  1 
ATOM   851   H  HD21 . ASN   A 1 61  ? 11.183  -18.767 -1.683  1.00 76.44 ? 60  ASN   A HD21 1 
ATOM   852   H  HD22 . ASN   A 1 61  ? 11.439  -19.495 -0.409  1.00 76.44 ? 60  ASN   A HD22 1 
ATOM   853   N  N    . ASP   A 1 62  ? 7.710   -16.624 1.692   1.00 45.93 ? 61  ASP   A N    1 
ATOM   854   C  CA   . ASP   A 1 62  ? 6.679   -17.370 2.411   1.00 49.36 ? 61  ASP   A CA   1 
ATOM   855   C  C    . ASP   A 1 62  ? 5.993   -16.416 3.387   1.00 51.52 ? 61  ASP   A C    1 
ATOM   856   O  O    . ASP   A 1 62  ? 6.439   -15.289 3.606   1.00 47.12 ? 61  ASP   A O    1 
ATOM   857   C  CB   . ASP   A 1 62  ? 7.241   -18.593 3.157   1.00 46.12 ? 61  ASP   A CB   1 
ATOM   858   C  CG   . ASP   A 1 62  ? 8.340   -18.246 4.130   1.00 53.23 ? 61  ASP   A CG   1 
ATOM   859   O  OD1  . ASP   A 1 62  ? 8.144   -17.325 4.960   1.00 52.19 ? 61  ASP   A OD1  1 
ATOM   860   O  OD2  . ASP   A 1 62  ? 9.409   -18.896 4.061   1.00 61.06 ? 61  ASP   A OD2  1 
ATOM   861   H  H    . ASP   A 1 62  ? 8.142   -16.080 2.198   1.00 55.11 ? 61  ASP   A H    1 
ATOM   862   H  HA   . ASP   A 1 62  ? 6.027   -17.698 1.773   1.00 59.23 ? 61  ASP   A HA   1 
ATOM   863   H  HB2  . ASP   A 1 62  ? 6.523   -19.013 3.657   1.00 55.35 ? 61  ASP   A HB2  1 
ATOM   864   H  HB3  . ASP   A 1 62  ? 7.603   -19.217 2.509   1.00 55.35 ? 61  ASP   A HB3  1 
ATOM   865   N  N    . ASP   A 1 63  ? 4.882   -16.867 3.970   1.00 51.34 ? 62  ASP   A N    1 
ATOM   866   C  CA   . ASP   A 1 63  ? 4.066   -15.969 4.783   1.00 45.14 ? 62  ASP   A CA   1 
ATOM   867   C  C    . ASP   A 1 63  ? 4.781   -15.543 6.060   1.00 44.00 ? 62  ASP   A C    1 
ATOM   868   O  O    . ASP   A 1 63  ? 4.621   -14.405 6.514   1.00 42.72 ? 62  ASP   A O    1 
ATOM   869   C  CB   . ASP   A 1 63  ? 2.736   -16.642 5.105   1.00 47.93 ? 62  ASP   A CB   1 
ATOM   870   C  CG   . ASP   A 1 63  ? 1.735   -16.517 3.969   1.00 55.92 ? 62  ASP   A CG   1 
ATOM   871   O  OD1  . ASP   A 1 63  ? 0.565   -16.913 4.157   1.00 63.95 ? 62  ASP   A OD1  1 
ATOM   872   O  OD2  . ASP   A 1 63  ? 2.118   -16.023 2.884   1.00 61.13 ? 62  ASP   A OD2  1 
ATOM   873   H  H    . ASP   A 1 63  ? 4.585   -17.672 3.911   1.00 61.61 ? 62  ASP   A H    1 
ATOM   874   H  HA   . ASP   A 1 63  ? 3.888   -15.163 4.274   1.00 54.17 ? 62  ASP   A HA   1 
ATOM   875   H  HB2  . ASP   A 1 63  ? 2.889   -17.586 5.269   1.00 57.52 ? 62  ASP   A HB2  1 
ATOM   876   H  HB3  . ASP   A 1 63  ? 2.352   -16.227 5.893   1.00 57.52 ? 62  ASP   A HB3  1 
ATOM   877   N  N    . THR   A 1 64  ? 5.570   -16.432 6.656   1.00 37.85 ? 63  THR   A N    1 
ATOM   878   C  CA   . THR   A 1 64  ? 6.344   -16.045 7.830   1.00 42.98 ? 63  THR   A CA   1 
ATOM   879   C  C    . THR   A 1 64  ? 7.308   -14.908 7.505   1.00 42.51 ? 63  THR   A C    1 
ATOM   880   O  O    . THR   A 1 64  ? 7.420   -13.939 8.266   1.00 36.83 ? 63  THR   A O    1 
ATOM   881   C  CB   . THR   A 1 64  ? 7.104   -17.248 8.399   1.00 42.14 ? 63  THR   A CB   1 
ATOM   882   O  OG1  . THR   A 1 64  ? 6.188   -18.314 8.677   1.00 47.24 ? 63  THR   A OG1  1 
ATOM   883   C  CG2  . THR   A 1 64  ? 7.853   -16.862 9.669   1.00 43.69 ? 63  THR   A CG2  1 
ATOM   884   H  H    . THR   A 1 64  ? 5.673   -17.248 6.406   1.00 45.42 ? 63  THR   A H    1 
ATOM   885   H  HA   . THR   A 1 64  ? 5.726   -15.737 8.512   1.00 51.58 ? 63  THR   A HA   1 
ATOM   886   H  HB   . THR   A 1 64  ? 7.757   -17.554 7.750   1.00 50.56 ? 63  THR   A HB   1 
ATOM   887   H  HG1  . THR   A 1 64  ? 6.606   -18.986 8.959   1.00 56.69 ? 63  THR   A HG1  1 
ATOM   888   H  HG21 . THR   A 1 64  ? 8.026   -17.651 10.206  1.00 52.42 ? 63  THR   A HG21 1 
ATOM   889   H  HG22 . THR   A 1 64  ? 8.698   -16.444 9.442   1.00 52.42 ? 63  THR   A HG22 1 
ATOM   890   H  HG23 . THR   A 1 64  ? 7.323   -16.237 10.190  1.00 52.42 ? 63  THR   A HG23 1 
ATOM   891   N  N    . LEU   A 1 65  ? 8.041   -15.028 6.396   1.00 38.82 ? 64  LEU   A N    1 
ATOM   892   C  CA   . LEU   A 1 65  ? 8.981   -13.976 6.027   1.00 35.34 ? 64  LEU   A CA   1 
ATOM   893   C  C    . LEU   A 1 65  ? 8.236   -12.699 5.657   1.00 35.32 ? 64  LEU   A C    1 
ATOM   894   O  O    . LEU   A 1 65  ? 8.708   -11.595 5.946   1.00 28.95 ? 64  LEU   A O    1 
ATOM   895   C  CB   . LEU   A 1 65  ? 9.856   -14.458 4.870   1.00 34.24 ? 64  LEU   A CB   1 
ATOM   896   C  CG   . LEU   A 1 65  ? 10.882  -15.520 5.288   1.00 39.01 ? 64  LEU   A CG   1 
ATOM   897   C  CD1  . LEU   A 1 65  ? 11.665  -15.962 4.064   1.00 41.43 ? 64  LEU   A CD1  1 
ATOM   898   C  CD2  . LEU   A 1 65  ? 11.855  -15.058 6.362   1.00 37.59 ? 64  LEU   A CD2  1 
ATOM   899   H  H    . LEU   A 1 65  ? 8.013   -15.694 5.853   1.00 46.59 ? 64  LEU   A H    1 
ATOM   900   H  HA   . LEU   A 1 65  ? 9.564   -13.777 6.776   1.00 42.41 ? 64  LEU   A HA   1 
ATOM   901   H  HB2  . LEU   A 1 65  ? 9.287   -14.845 4.187   1.00 41.08 ? 64  LEU   A HB2  1 
ATOM   902   H  HB3  . LEU   A 1 65  ? 10.341  -13.700 4.508   1.00 41.08 ? 64  LEU   A HB3  1 
ATOM   903   H  HG   . LEU   A 1 65  ? 10.385  -16.257 5.676   1.00 46.82 ? 64  LEU   A HG   1 
ATOM   904   H  HD11 . LEU   A 1 65  ? 11.973  -16.872 4.198   1.00 49.72 ? 64  LEU   A HD11 1 
ATOM   905   H  HD12 . LEU   A 1 65  ? 11.086  -15.921 3.287   1.00 49.72 ? 64  LEU   A HD12 1 
ATOM   906   H  HD13 . LEU   A 1 65  ? 12.423  -15.370 3.943   1.00 49.72 ? 64  LEU   A HD13 1 
ATOM   907   H  HD21 . LEU   A 1 65  ? 12.747  -15.360 6.131   1.00 45.10 ? 64  LEU   A HD21 1 
ATOM   908   H  HD22 . LEU   A 1 65  ? 11.836  -14.089 6.410   1.00 45.10 ? 64  LEU   A HD22 1 
ATOM   909   H  HD23 . LEU   A 1 65  ? 11.588  -15.436 7.215   1.00 45.10 ? 64  LEU   A HD23 1 
ATOM   910   N  N    . ARG   A 1 66  ? 7.077   -12.828 5.035   1.00 32.90 ? 65  ARG   A N    1 
ATOM   911   C  CA   . ARG   A 1 66  ? 6.301   -11.673 4.642   1.00 37.35 ? 65  ARG   A CA   1 
ATOM   912   C  C    . ARG   A 1 66  ? 5.874   -10.871 5.865   1.00 37.57 ? 65  ARG   A C    1 
ATOM   913   O  O    . ARG   A 1 66  ? 5.968   -9.671  5.902   1.00 31.87 ? 65  ARG   A O    1 
ATOM   914   C  CB   . ARG   A 1 66  ? 5.098   -12.079 3.796   1.00 40.43 ? 65  ARG   A CB   1 
ATOM   915   C  CG   . ARG   A 1 66  ? 5.418   -12.201 2.334   1.00 42.37 ? 65  ARG   A CG   1 
ATOM   916   C  CD   . ARG   A 1 66  ? 4.241   -12.608 1.477   1.00 52.73 ? 65  ARG   A CD   1 
ATOM   917   N  NE   . ARG   A 1 66  ? 4.676   -13.488 0.423   1.00 56.66 ? 65  ARG   A NE   1 
ATOM   918   C  CZ   . ARG   A 1 66  ? 4.307   -14.753 0.310   1.00 58.28 ? 65  ARG   A CZ   1 
ATOM   919   N  NH1  . ARG   A 1 66  ? 3.451   -15.284 1.142   1.00 55.62 ? 65  ARG   A NH1  1 
ATOM   920   N  NH2  . ARG   A 1 66  ? 4.789   -15.485 -0.650  1.00 63.70 ? 65  ARG   A NH2  1 
ATOM   921   H  H    . ARG   A 1 66  ? 6.716   -13.581 4.830   1.00 39.48 ? 65  ARG   A H    1 
ATOM   922   H  HA   . ARG   A 1 66  ? 6.866   -11.092 4.091   1.00 44.82 ? 65  ARG   A HA   1 
ATOM   923   H  HB2  . ARG   A 1 66  ? 4.772   -12.939 4.103   1.00 48.52 ? 65  ARG   A HB2  1 
ATOM   924   H  HB3  . ARG   A 1 66  ? 4.405   -11.407 3.893   1.00 48.52 ? 65  ARG   A HB3  1 
ATOM   925   H  HG2  . ARG   A 1 66  ? 5.735   -11.343 2.012   1.00 50.84 ? 65  ARG   A HG2  1 
ATOM   926   H  HG3  . ARG   A 1 66  ? 6.111   -12.871 2.222   1.00 50.84 ? 65  ARG   A HG3  1 
ATOM   927   H  HD2  . ARG   A 1 66  ? 3.591   -13.078 2.022   1.00 63.27 ? 65  ARG   A HD2  1 
ATOM   928   H  HD3  . ARG   A 1 66  ? 3.842   -11.820 1.077   1.00 63.27 ? 65  ARG   A HD3  1 
ATOM   929   H  HE   . ARG   A 1 66  ? 5.226   -13.112 -0.282  1.00 68.00 ? 65  ARG   A HE   1 
ATOM   930   H  HH11 . ARG   A 1 66  ? 3.132   -14.815 1.789   1.00 66.74 ? 65  ARG   A HH11 1 
ATOM   931   H  HH12 . ARG   A 1 66  ? 3.214   -16.106 1.050   1.00 66.74 ? 65  ARG   A HH12 1 
ATOM   932   H  HH21 . ARG   A 1 66  ? 5.344   -15.145 -1.213  1.00 76.44 ? 65  ARG   A HH21 1 
ATOM   933   H  HH22 . ARG   A 1 66  ? 4.532   -16.301 -0.739  1.00 76.44 ? 65  ARG   A HH22 1 
ATOM   934   N  N    . VAL   A 1 67  ? 5.414   -11.560 6.871   1.00 33.37 ? 66  VAL   A N    1 
ATOM   935   C  CA   . VAL   A 1 67  ? 5.019   -10.893 8.099   1.00 36.00 ? 66  VAL   A CA   1 
ATOM   936   C  C    . VAL   A 1 67  ? 6.230   -10.284 8.783   1.00 31.52 ? 66  VAL   A C    1 
ATOM   937   O  O    . VAL   A 1 67  ? 6.161   -9.159  9.293   1.00 30.14 ? 66  VAL   A O    1 
ATOM   938   C  CB   . VAL   A 1 67  ? 4.277   -11.863 9.032   1.00 39.85 ? 66  VAL   A CB   1 
ATOM   939   C  CG1  . VAL   A 1 67  ? 4.006   -11.170 10.357  1.00 36.65 ? 66  VAL   A CG1  1 
ATOM   940   C  CG2  . VAL   A 1 67  ? 3.012   -12.337 8.372   1.00 40.77 ? 66  VAL   A CG2  1 
ATOM   941   H  H    . VAL   A 1 67  ? 5.334   -12.417 6.888   1.00 40.04 ? 66  VAL   A H    1 
ATOM   942   H  HA   . VAL   A 1 67  ? 4.407   -10.176 7.869   1.00 43.20 ? 66  VAL   A HA   1 
ATOM   943   H  HB   . VAL   A 1 67  ? 4.817   -12.649 9.213   1.00 47.82 ? 66  VAL   A HB   1 
ATOM   944   H  HG11 . VAL   A 1 67  ? 3.278   -11.625 10.809  1.00 43.98 ? 66  VAL   A HG11 1 
ATOM   945   H  HG12 . VAL   A 1 67  ? 4.808   -11.205 10.902  1.00 43.98 ? 66  VAL   A HG12 1 
ATOM   946   H  HG13 . VAL   A 1 67  ? 3.763   -10.246 10.186  1.00 43.98 ? 66  VAL   A HG13 1 
ATOM   947   H  HG21 . VAL   A 1 67  ? 3.000   -13.307 8.371   1.00 48.92 ? 66  VAL   A HG21 1 
ATOM   948   H  HG22 . VAL   A 1 67  ? 2.251   -11.997 8.868   1.00 48.92 ? 66  VAL   A HG22 1 
ATOM   949   H  HG23 . VAL   A 1 67  ? 2.988   -12.005 7.461   1.00 48.92 ? 66  VAL   A HG23 1 
ATOM   950   N  N    . GLU   A 1 68  ? 7.350   -11.015 8.832   1.00 28.68 ? 67  GLU   A N    1 
ATOM   951   C  CA   . GLU   A 1 68  ? 8.540   -10.467 9.484   1.00 31.30 ? 67  GLU   A CA   1 
ATOM   952   C  C    . GLU   A 1 68  ? 9.004   -9.191  8.777   1.00 26.81 ? 67  GLU   A C    1 
ATOM   953   O  O    . GLU   A 1 68  ? 9.376   -8.211  9.430   1.00 27.55 ? 67  GLU   A O    1 
ATOM   954   C  CB   . GLU   A 1 68  ? 9.682   -11.493 9.509   1.00 27.87 ? 67  GLU   A CB   1 
ATOM   955   C  CG   . GLU   A 1 68  ? 9.506   -12.577 10.582  1.00 33.33 ? 67  GLU   A CG   1 
ATOM   956   C  CD   . GLU   A 1 68  ? 10.493  -13.771 10.489  1.00 36.33 ? 67  GLU   A CD   1 
ATOM   957   O  OE1  . GLU   A 1 68  ? 11.314  -13.826 9.557   1.00 32.28 ? 67  GLU   A OE1  1 
ATOM   958   O  OE2  . GLU   A 1 68  ? 10.450  -14.652 11.389  1.00 37.02 ? 67  GLU   A OE2  1 
ATOM   959   H  H    . GLU   A 1 68  ? 7.443   -11.804 8.504   1.00 34.41 ? 67  GLU   A H    1 
ATOM   960   H  HA   . GLU   A 1 68  ? 8.311   -10.260 10.404  1.00 37.56 ? 67  GLU   A HA   1 
ATOM   961   H  HB2  . GLU   A 1 68  ? 9.727   -11.933 8.646   1.00 33.45 ? 67  GLU   A HB2  1 
ATOM   962   H  HB3  . GLU   A 1 68  ? 10.515  -11.029 9.689   1.00 33.45 ? 67  GLU   A HB3  1 
ATOM   963   H  HG2  . GLU   A 1 68  ? 9.629   -12.168 11.453  1.00 40.00 ? 67  GLU   A HG2  1 
ATOM   964   H  HG3  . GLU   A 1 68  ? 8.609   -12.937 10.509  1.00 40.00 ? 67  GLU   A HG3  1 
ATOM   965   N  N    . ALA   A 1 69  ? 9.025   -9.204  7.444   1.00 23.54 ? 68  ALA   A N    1 
ATOM   966   C  CA   . ALA   A 1 69  ? 9.479   -8.036  6.689   1.00 25.33 ? 68  ALA   A CA   1 
ATOM   967   C  C    . ALA   A 1 69  ? 8.555   -6.846  6.927   1.00 28.63 ? 68  ALA   A C    1 
ATOM   968   O  O    . ALA   A 1 69  ? 9.006   -5.733  7.213   1.00 25.44 ? 68  ALA   A O    1 
ATOM   969   C  CB   . ALA   A 1 69  ? 9.562   -8.369  5.202   1.00 26.16 ? 68  ALA   A CB   1 
ATOM   970   H  H    . ALA   A 1 69  ? 8.784   -9.871  6.956   1.00 28.24 ? 68  ALA   A H    1 
ATOM   971   H  HA   . ALA   A 1 69  ? 10.369  -7.794  6.988   1.00 30.39 ? 68  ALA   A HA   1 
ATOM   972   H  HB1  . ALA   A 1 69  ? 9.761   -7.559  4.707   1.00 31.39 ? 68  ALA   A HB1  1 
ATOM   973   H  HB2  . ALA   A 1 69  ? 10.266  -9.022  5.064   1.00 31.39 ? 68  ALA   A HB2  1 
ATOM   974   H  HB3  . ALA   A 1 69  ? 8.712   -8.734  4.911   1.00 31.39 ? 68  ALA   A HB3  1 
ATOM   975   N  N    . PHE   A 1 70  ? 7.247   -7.067  6.840   1.00 26.57 ? 69  PHE   A N    1 
ATOM   976   C  CA   . PHE   A 1 70  ? 6.335   -5.950  7.030   1.00 28.54 ? 69  PHE   A CA   1 
ATOM   977   C  C    . PHE   A 1 70  ? 6.437   -5.371  8.428   1.00 28.16 ? 69  PHE   A C    1 
ATOM   978   O  O    . PHE   A 1 70  ? 6.408   -4.146  8.603   1.00 27.12 ? 69  PHE   A O    1 
ATOM   979   C  CB   . PHE   A 1 70  ? 4.896   -6.364  6.767   1.00 34.66 ? 69  PHE   A CB   1 
ATOM   980   C  CG   . PHE   A 1 70  ? 3.928   -5.230  6.960   1.00 29.63 ? 69  PHE   A CG   1 
ATOM   981   C  CD1  . PHE   A 1 70  ? 3.901   -4.185  6.057   1.00 33.30 ? 69  PHE   A CD1  1 
ATOM   982   C  CD2  . PHE   A 1 70  ? 3.113   -5.175  8.067   1.00 41.30 ? 69  PHE   A CD2  1 
ATOM   983   C  CE1  . PHE   A 1 70  ? 3.025   -3.132  6.220   1.00 38.23 ? 69  PHE   A CE1  1 
ATOM   984   C  CE2  . PHE   A 1 70  ? 2.239   -4.122  8.244   1.00 44.96 ? 69  PHE   A CE2  1 
ATOM   985   C  CZ   . PHE   A 1 70  ? 2.202   -3.098  7.318   1.00 40.40 ? 69  PHE   A CZ   1 
ATOM   986   H  H    . PHE   A 1 70  ? 6.877   -7.826  6.679   1.00 31.88 ? 69  PHE   A H    1 
ATOM   987   H  HA   . PHE   A 1 70  ? 6.581   -5.268  6.385   1.00 34.24 ? 69  PHE   A HA   1 
ATOM   988   H  HB2  . PHE   A 1 70  ? 4.818   -6.674  5.851   1.00 41.59 ? 69  PHE   A HB2  1 
ATOM   989   H  HB3  . PHE   A 1 70  ? 4.654   -7.075  7.380   1.00 41.59 ? 69  PHE   A HB3  1 
ATOM   990   H  HD1  . PHE   A 1 70  ? 4.481   -4.191  5.330   1.00 39.96 ? 69  PHE   A HD1  1 
ATOM   991   H  HD2  . PHE   A 1 70  ? 3.152   -5.853  8.702   1.00 49.56 ? 69  PHE   A HD2  1 
ATOM   992   H  HE1  . PHE   A 1 70  ? 2.991   -2.449  5.590   1.00 45.88 ? 69  PHE   A HE1  1 
ATOM   993   H  HE2  . PHE   A 1 70  ? 1.677   -4.102  8.984   1.00 53.95 ? 69  PHE   A HE2  1 
ATOM   994   H  HZ   . PHE   A 1 70  ? 1.619   -2.384  7.439   1.00 48.48 ? 69  PHE   A HZ   1 
ATOM   995   N  N    . GLU   A 1 71  ? 6.522   -6.233  9.450   1.00 23.40 ? 70  GLU   A N    1 
ATOM   996   C  CA   . GLU   A 1 71  ? 6.609   -5.742  10.823  1.00 25.77 ? 70  GLU   A CA   1 
ATOM   997   C  C    . GLU   A 1 71  ? 7.885   -4.955  11.053  1.00 24.03 ? 70  GLU   A C    1 
ATOM   998   O  O    . GLU   A 1 71  ? 7.901   -4.034  11.877  1.00 26.47 ? 70  GLU   A O    1 
ATOM   999   C  CB   . GLU   A 1 71  ? 6.520   -6.913  11.812  1.00 30.12 ? 70  GLU   A CB   1 
ATOM   1000  C  CG   . GLU   A 1 71  ? 5.090   -7.428  11.932  1.00 31.34 ? 70  GLU   A CG   1 
ATOM   1001  C  CD   . GLU   A 1 71  ? 4.911   -8.548  12.950  1.00 37.03 ? 70  GLU   A CD   1 
ATOM   1002  O  OE1  . GLU   A 1 71  ? 5.911   -8.984  13.569  1.00 39.90 ? 70  GLU   A OE1  1 
ATOM   1003  O  OE2  . GLU   A 1 71  ? 3.745   -8.980  13.132  1.00 44.37 ? 70  GLU   A OE2  1 
ATOM   1004  H  H    . GLU   A 1 71  ? 6.529   -7.090  9.374   1.00 28.08 ? 70  GLU   A H    1 
ATOM   1005  H  HA   . GLU   A 1 71  ? 5.857   -5.153  10.991  1.00 30.92 ? 70  GLU   A HA   1 
ATOM   1006  H  HB2  . GLU   A 1 71  ? 7.082   -7.640  11.502  1.00 36.14 ? 70  GLU   A HB2  1 
ATOM   1007  H  HB3  . GLU   A 1 71  ? 6.813   -6.617  12.688  1.00 36.14 ? 70  GLU   A HB3  1 
ATOM   1008  H  HG2  . GLU   A 1 71  ? 4.517   -6.692  12.201  1.00 37.61 ? 70  GLU   A HG2  1 
ATOM   1009  H  HG3  . GLU   A 1 71  ? 4.810   -7.768  11.068  1.00 37.61 ? 70  GLU   A HG3  1 
ATOM   1010  N  N    . TYR   A 1 72  ? 8.962   -5.290  10.337  1.00 25.69 ? 71  TYR   A N    1 
ATOM   1011  C  CA   . TYR   A 1 72  ? 10.226  -4.609  10.568  1.00 24.04 ? 71  TYR   A CA   1 
ATOM   1012  C  C    . TYR   A 1 72  ? 10.352  -3.309  9.767   1.00 20.82 ? 71  TYR   A C    1 
ATOM   1013  O  O    . TYR   A 1 72  ? 10.776  -2.292  10.328  1.00 24.06 ? 71  TYR   A O    1 
ATOM   1014  C  CB   . TYR   A 1 72  ? 11.403  -5.541  10.243  1.00 23.85 ? 71  TYR   A CB   1 
ATOM   1015  C  CG   . TYR   A 1 72  ? 12.726  -5.071  10.846  1.00 22.57 ? 71  TYR   A CG   1 
ATOM   1016  C  CD1  . TYR   A 1 72  ? 12.882  -4.937  12.227  1.00 21.06 ? 71  TYR   A CD1  1 
ATOM   1017  C  CD2  . TYR   A 1 72  ? 13.815  -4.748  10.035  1.00 22.76 ? 71  TYR   A CD2  1 
ATOM   1018  C  CE1  . TYR   A 1 72  ? 14.089  -4.503  12.787  1.00 25.41 ? 71  TYR   A CE1  1 
ATOM   1019  C  CE2  . TYR   A 1 72  ? 15.045  -4.310  10.595  1.00 23.76 ? 71  TYR   A CE2  1 
ATOM   1020  C  CZ   . TYR   A 1 72  ? 15.162  -4.179  11.964  1.00 22.51 ? 71  TYR   A CZ   1 
ATOM   1021  O  OH   . TYR   A 1 72  ? 16.337  -3.744  12.555  1.00 24.81 ? 71  TYR   A OH   1 
ATOM   1022  H  H    . TYR   A 1 72  ? 8.980   -5.895  9.726   1.00 30.83 ? 71  TYR   A H    1 
ATOM   1023  H  HA   . TYR   A 1 72  ? 10.282  -4.381  11.510  1.00 28.85 ? 71  TYR   A HA   1 
ATOM   1024  H  HB2  . TYR   A 1 72  ? 11.211  -6.424  10.596  1.00 28.62 ? 71  TYR   A HB2  1 
ATOM   1025  H  HB3  . TYR   A 1 72  ? 11.512  -5.584  9.280   1.00 28.62 ? 71  TYR   A HB3  1 
ATOM   1026  H  HD1  . TYR   A 1 72  ? 12.168  -5.142  12.787  1.00 25.27 ? 71  TYR   A HD1  1 
ATOM   1027  H  HD2  . TYR   A 1 72  ? 13.734  -4.821  9.112   1.00 27.31 ? 71  TYR   A HD2  1 
ATOM   1028  H  HE1  . TYR   A 1 72  ? 14.174  -4.431  13.710  1.00 30.49 ? 71  TYR   A HE1  1 
ATOM   1029  H  HE2  . TYR   A 1 72  ? 15.767  -4.114  10.042  1.00 28.51 ? 71  TYR   A HE2  1 
ATOM   1030  H  HH   . TYR   A 1 72  ? 16.431  -4.105  13.308  1.00 29.77 ? 71  TYR   A HH   1 
ATOM   1031  N  N    . TYR   A 1 73  ? 9.941   -3.306  8.498   1.00 22.16 ? 72  TYR   A N    1 
ATOM   1032  C  CA   . TYR   A 1 73  ? 10.140  -2.161  7.606   1.00 23.21 ? 72  TYR   A CA   1 
ATOM   1033  C  C    . TYR   A 1 73  ? 8.895   -1.298  7.403   1.00 27.51 ? 72  TYR   A C    1 
ATOM   1034  O  O    . TYR   A 1 73  ? 9.018   -0.166  6.905   1.00 26.23 ? 72  TYR   A O    1 
ATOM   1035  C  CB   . TYR   A 1 73  ? 10.608  -2.641  6.219   1.00 22.41 ? 72  TYR   A CB   1 
ATOM   1036  C  CG   . TYR   A 1 73  ? 11.894  -3.444  6.255   1.00 23.02 ? 72  TYR   A CG   1 
ATOM   1037  C  CD1  . TYR   A 1 73  ? 13.097  -2.842  6.579   1.00 23.05 ? 72  TYR   A CD1  1 
ATOM   1038  C  CD2  . TYR   A 1 73  ? 11.898  -4.814  5.972   1.00 25.97 ? 72  TYR   A CD2  1 
ATOM   1039  C  CE1  . TYR   A 1 73  ? 14.278  -3.569  6.632   1.00 21.79 ? 72  TYR   A CE1  1 
ATOM   1040  C  CE2  . TYR   A 1 73  ? 13.059  -5.544  6.031   1.00 23.98 ? 72  TYR   A CE2  1 
ATOM   1041  C  CZ   . TYR   A 1 73  ? 14.242  -4.920  6.361   1.00 25.39 ? 72  TYR   A CZ   1 
ATOM   1042  O  OH   . TYR   A 1 73  ? 15.393  -5.645  6.433   1.00 24.82 ? 72  TYR   A OH   1 
ATOM   1043  H  H    . TYR   A 1 73  ? 9.538   -3.967  8.123   1.00 26.59 ? 72  TYR   A H    1 
ATOM   1044  H  HA   . TYR   A 1 73  ? 10.830  -1.603  7.999   1.00 27.85 ? 72  TYR   A HA   1 
ATOM   1045  H  HB2  . TYR   A 1 73  ? 9.918   -3.203  5.834   1.00 26.90 ? 72  TYR   A HB2  1 
ATOM   1046  H  HB3  . TYR   A 1 73  ? 10.757  -1.866  5.655   1.00 26.90 ? 72  TYR   A HB3  1 
ATOM   1047  H  HD1  . TYR   A 1 73  ? 13.114  -1.931  6.766   1.00 27.66 ? 72  TYR   A HD1  1 
ATOM   1048  H  HD2  . TYR   A 1 73  ? 11.102  -5.237  5.742   1.00 31.17 ? 72  TYR   A HD2  1 
ATOM   1049  H  HE1  . TYR   A 1 73  ? 15.081  -3.152  6.847   1.00 26.14 ? 72  TYR   A HE1  1 
ATOM   1050  H  HE2  . TYR   A 1 73  ? 13.047  -6.455  5.848   1.00 28.78 ? 72  TYR   A HE2  1 
ATOM   1051  H  HH   . TYR   A 1 73  ? 15.345  -6.312  5.925   1.00 29.78 ? 72  TYR   A HH   1 
ATOM   1052  N  N    . HIS   A 1 74  ? 7.710   -1.811  7.725   1.00 25.57 ? 73  HIS   A N    1 
ATOM   1053  C  CA   . HIS   A 1 74  ? 6.445   -1.108  7.462   1.00 29.06 ? 73  HIS   A CA   1 
ATOM   1054  C  C    . HIS   A 1 74  ? 6.257   -0.781  5.979   1.00 33.58 ? 73  HIS   A C    1 
ATOM   1055  O  O    . HIS   A 1 74  ? 5.768   0.295   5.612   1.00 34.49 ? 73  HIS   A O    1 
ATOM   1056  C  CB   . HIS   A 1 74  ? 6.325   0.164   8.301   1.00 26.99 ? 73  HIS   A CB   1 
ATOM   1057  C  CG   . HIS   A 1 74  ? 6.168   -0.085  9.758   1.00 25.98 ? 73  HIS   A CG   1 
ATOM   1058  N  ND1  . HIS   A 1 74  ? 5.870   0.920   10.658  1.00 27.06 ? 73  HIS   A ND1  1 
ATOM   1059  C  CD2  . HIS   A 1 74  ? 6.279   -1.225  10.488  1.00 26.47 ? 73  HIS   A CD2  1 
ATOM   1060  C  CE1  . HIS   A 1 74  ? 5.807   0.409   11.875  1.00 29.18 ? 73  HIS   A CE1  1 
ATOM   1061  N  NE2  . HIS   A 1 74  ? 6.040   -0.890  11.799  1.00 26.89 ? 73  HIS   A NE2  1 
ATOM   1062  H  H    . HIS   A 1 74  ? 7.605   -2.577  8.104   1.00 30.68 ? 73  HIS   A H    1 
ATOM   1063  H  HA   . HIS   A 1 74  ? 5.729   -1.711  7.714   1.00 34.87 ? 73  HIS   A HA   1 
ATOM   1064  H  HB2  . HIS   A 1 74  ? 7.127   0.695   8.178   1.00 32.39 ? 73  HIS   A HB2  1 
ATOM   1065  H  HB3  . HIS   A 1 74  ? 5.548   0.662   8.002   1.00 32.39 ? 73  HIS   A HB3  1 
ATOM   1066  H  HD2  . HIS   A 1 74  ? 6.480   -2.073  10.162  1.00 31.76 ? 73  HIS   A HD2  1 
ATOM   1067  H  HE1  . HIS   A 1 74  ? 5.629   0.885   12.654  1.00 35.01 ? 73  HIS   A HE1  1 
ATOM   1068  H  HE2  . HIS   A 1 74  ? 6.041   -1.437  12.463  1.00 32.27 ? 73  HIS   A HE2  1 
ATOM   1069  N  N    . THR   A 1 75  ? 6.621   -1.717  5.110   1.00 30.93 ? 74  THR   A N    1 
ATOM   1070  C  CA   . THR   A 1 75  ? 6.355   -1.576  3.689   1.00 33.85 ? 74  THR   A CA   1 
ATOM   1071  C  C    . THR   A 1 75  ? 5.996   -2.934  3.104   1.00 38.02 ? 74  THR   A C    1 
ATOM   1072  O  O    . THR   A 1 75  ? 6.443   -3.973  3.590   1.00 34.27 ? 74  THR   A O    1 
ATOM   1073  C  CB   . THR   A 1 75  ? 7.557   -0.968  2.924   1.00 32.58 ? 74  THR   A CB   1 
ATOM   1074  O  OG1  . THR   A 1 75  ? 7.179   -0.756  1.559   1.00 39.50 ? 74  THR   A OG1  1 
ATOM   1075  C  CG2  . THR   A 1 75  ? 8.775   -1.864  2.962   1.00 33.01 ? 74  THR   A CG2  1 
ATOM   1076  H  H    . THR   A 1 75  ? 7.026   -2.445  5.322   1.00 37.12 ? 74  THR   A H    1 
ATOM   1077  H  HA   . THR   A 1 75  ? 5.597   -0.983  3.566   1.00 40.62 ? 74  THR   A HA   1 
ATOM   1078  H  HB   . THR   A 1 75  ? 7.803   -0.132  3.348   1.00 39.10 ? 74  THR   A HB   1 
ATOM   1079  H  HG1  . THR   A 1 75  ? 7.836   -0.895  1.055   1.00 47.40 ? 74  THR   A HG1  1 
ATOM   1080  H  HG21 . THR   A 1 75  ? 9.582   -1.328  2.913   1.00 39.62 ? 74  THR   A HG21 1 
ATOM   1081  H  HG22 . THR   A 1 75  ? 8.785   -2.375  3.786   1.00 39.62 ? 74  THR   A HG22 1 
ATOM   1082  H  HG23 . THR   A 1 75  ? 8.759   -2.477  2.210   1.00 39.62 ? 74  THR   A HG23 1 
ATOM   1083  N  N    . THR   A 1 76  ? 5.153   -2.910  2.071   1.00 37.37 ? 75  THR   A N    1 
ATOM   1084  C  CA   . THR   A 1 76  ? 4.815   -4.091  1.289   1.00 39.96 ? 75  THR   A CA   1 
ATOM   1085  C  C    . THR   A 1 76  ? 5.382   -4.036  -0.125  1.00 40.86 ? 75  THR   A C    1 
ATOM   1086  O  O    . THR   A 1 76  ? 5.171   -4.969  -0.903  1.00 42.26 ? 75  THR   A O    1 
ATOM   1087  C  CB   . THR   A 1 76  ? 3.292   -4.252  1.224   1.00 48.05 ? 75  THR   A CB   1 
ATOM   1088  O  OG1  . THR   A 1 76  ? 2.683   -2.955  1.144   1.00 54.16 ? 75  THR   A OG1  1 
ATOM   1089  C  CG2  . THR   A 1 76  ? 2.794   -4.976  2.475   1.00 53.25 ? 75  THR   A CG2  1 
ATOM   1090  H  H    . THR   A 1 76  ? 4.754   -2.198  1.799   1.00 44.84 ? 75  THR   A H    1 
ATOM   1091  H  HA   . THR   A 1 76  ? 5.182   -4.875  1.727   1.00 47.95 ? 75  THR   A HA   1 
ATOM   1092  H  HB   . THR   A 1 76  ? 3.043   -4.773  0.445   1.00 57.66 ? 75  THR   A HB   1 
ATOM   1093  H  HG1  . THR   A 1 76  ? 1.847   -3.032  1.109   1.00 64.99 ? 75  THR   A HG1  1 
ATOM   1094  H  HG21 . THR   A 1 76  ? 1.831   -5.081  2.436   1.00 63.90 ? 75  THR   A HG21 1 
ATOM   1095  H  HG22 . THR   A 1 76  ? 3.204   -5.853  2.537   1.00 63.90 ? 75  THR   A HG22 1 
ATOM   1096  H  HG23 . THR   A 1 76  ? 3.023   -4.465  3.267   1.00 63.90 ? 75  THR   A HG23 1 
ATOM   1097  N  N    . ASP   A 1 77  ? 6.103   -2.981  -0.467  1.00 36.55 ? 76  ASP   A N    1 
ATOM   1098  C  CA   . ASP   A 1 77  ? 6.773   -2.871  -1.755  1.00 33.38 ? 76  ASP   A CA   1 
ATOM   1099  C  C    . ASP   A 1 77  ? 7.710   -4.052  -1.951  1.00 34.56 ? 76  ASP   A C    1 
ATOM   1100  O  O    . ASP   A 1 77  ? 8.717   -4.153  -1.249  1.00 32.53 ? 76  ASP   A O    1 
ATOM   1101  C  CB   . ASP   A 1 77  ? 7.517   -1.535  -1.807  1.00 33.77 ? 76  ASP   A CB   1 
ATOM   1102  C  CG   . ASP   A 1 77  ? 8.229   -1.301  -3.113  1.00 34.28 ? 76  ASP   A CG   1 
ATOM   1103  O  OD1  . ASP   A 1 77  ? 8.288   -2.221  -3.954  1.00 35.67 ? 76  ASP   A OD1  1 
ATOM   1104  O  OD2  . ASP   A 1 77  ? 8.745   -0.179  -3.285  1.00 31.78 ? 76  ASP   A OD2  1 
ATOM   1105  H  H    . ASP   A 1 77  ? 6.223   -2.297  0.040   1.00 43.86 ? 76  ASP   A H    1 
ATOM   1106  H  HA   . ASP   A 1 77  ? 6.136   -2.896  -2.487  1.00 40.05 ? 76  ASP   A HA   1 
ATOM   1107  H  HB2  . ASP   A 1 77  ? 6.879   -0.815  -1.683  1.00 40.52 ? 76  ASP   A HB2  1 
ATOM   1108  H  HB3  . ASP   A 1 77  ? 8.179   -1.517  -1.099  1.00 40.52 ? 76  ASP   A HB3  1 
ATOM   1109  N  N    . PRO   A 1 78  ? 7.433   -4.957  -2.900  1.00 35.62 ? 77  PRO   A N    1 
ATOM   1110  C  CA   . PRO   A 1 78  ? 8.282   -6.155  -3.030  1.00 30.51 ? 77  PRO   A CA   1 
ATOM   1111  C  C    . PRO   A 1 78  ? 9.707   -5.849  -3.451  1.00 35.37 ? 77  PRO   A C    1 
ATOM   1112  O  O    . PRO   A 1 78  ? 10.583  -6.705  -3.277  1.00 33.86 ? 77  PRO   A O    1 
ATOM   1113  C  CB   . PRO   A 1 78  ? 7.561   -6.985  -4.112  1.00 37.29 ? 77  PRO   A CB   1 
ATOM   1114  C  CG   . PRO   A 1 78  ? 6.144   -6.425  -4.156  1.00 38.06 ? 77  PRO   A CG   1 
ATOM   1115  C  CD   . PRO   A 1 78  ? 6.329   -4.960  -3.884  1.00 38.08 ? 77  PRO   A CD   1 
ATOM   1116  H  HA   . PRO   A 1 78  ? 8.288   -6.645  -2.193  1.00 36.61 ? 77  PRO   A HA   1 
ATOM   1117  H  HB2  . PRO   A 1 78  ? 8.006   -6.873  -4.967  1.00 44.75 ? 77  PRO   A HB2  1 
ATOM   1118  H  HB3  . PRO   A 1 78  ? 7.557   -7.923  -3.862  1.00 44.75 ? 77  PRO   A HB3  1 
ATOM   1119  H  HG2  . PRO   A 1 78  ? 5.752   -6.573  -5.031  1.00 45.67 ? 77  PRO   A HG2  1 
ATOM   1120  H  HG3  . PRO   A 1 78  ? 5.596   -6.843  -3.473  1.00 45.67 ? 77  PRO   A HG3  1 
ATOM   1121  H  HD2  . PRO   A 1 78  ? 6.580   -4.484  -4.691  1.00 45.69 ? 77  PRO   A HD2  1 
ATOM   1122  H  HD3  . PRO   A 1 78  ? 5.524   -4.571  -3.506  1.00 45.69 ? 77  PRO   A HD3  1 
ATOM   1123  N  N    . SER   A 1 79  ? 9.962   -4.673  -4.024  1.00 30.45 ? 78  SER   A N    1 
ATOM   1124  C  CA   . SER   A 1 79  ? 11.299  -4.287  -4.450  1.00 31.13 ? 78  SER   A CA   1 
ATOM   1125  C  C    . SER   A 1 79  ? 12.128  -3.671  -3.333  1.00 27.58 ? 78  SER   A C    1 
ATOM   1126  O  O    . SER   A 1 79  ? 13.318  -3.414  -3.551  1.00 26.28 ? 78  SER   A O    1 
ATOM   1127  C  CB   . SER   A 1 79  ? 11.213  -3.309  -5.629  1.00 34.80 ? 78  SER   A CB   1 
ATOM   1128  O  OG   . SER   A 1 79  ? 10.820  -2.015  -5.188  1.00 29.76 ? 78  SER   A OG   1 
ATOM   1129  H  H    . SER   A 1 79  ? 9.366   -4.073  -4.179  1.00 36.53 ? 78  SER   A H    1 
ATOM   1130  H  HA   . SER   A 1 79  ? 11.765  -5.081  -4.755  1.00 37.36 ? 78  SER   A HA   1 
ATOM   1131  H  HB2  . SER   A 1 79  ? 12.084  -3.247  -6.051  1.00 41.76 ? 78  SER   A HB2  1 
ATOM   1132  H  HB3  . SER   A 1 79  ? 10.558  -3.638  -6.265  1.00 41.76 ? 78  SER   A HB3  1 
ATOM   1133  H  HG   . SER   A 1 79  ? 10.711  -1.508  -5.848  1.00 35.72 ? 78  SER   A HG   1 
ATOM   1134  N  N    . PHE   A 1 80  ? 11.541  -3.454  -2.149  1.00 28.53 ? 79  PHE   A N    1 
ATOM   1135  C  CA   . PHE   A 1 80  ? 12.229  -2.707  -1.093  1.00 28.35 ? 79  PHE   A CA   1 
ATOM   1136  C  C    . PHE   A 1 80  ? 13.521  -3.389  -0.663  1.00 25.48 ? 79  PHE   A C    1 
ATOM   1137  O  O    . PHE   A 1 80  ? 14.591  -2.768  -0.670  1.00 21.79 ? 79  PHE   A O    1 
ATOM   1138  C  CB   . PHE   A 1 80  ? 11.321  -2.503  0.114   1.00 29.92 ? 79  PHE   A CB   1 
ATOM   1139  C  CG   . PHE   A 1 80  ? 11.964  -1.710  1.212   1.00 24.96 ? 79  PHE   A CG   1 
ATOM   1140  C  CD1  . PHE   A 1 80  ? 11.889  -0.327  1.230   1.00 27.87 ? 79  PHE   A CD1  1 
ATOM   1141  C  CD2  . PHE   A 1 80  ? 12.676  -2.358  2.212   1.00 24.52 ? 79  PHE   A CD2  1 
ATOM   1142  C  CE1  . PHE   A 1 80  ? 12.503  0.412   2.247   1.00 25.42 ? 79  PHE   A CE1  1 
ATOM   1143  C  CE2  . PHE   A 1 80  ? 13.302  -1.651  3.193   1.00 22.69 ? 79  PHE   A CE2  1 
ATOM   1144  C  CZ   . PHE   A 1 80  ? 13.209  -0.244  3.221   1.00 24.90 ? 79  PHE   A CZ   1 
ATOM   1145  H  H    . PHE   A 1 80  ? 10.754  -3.727  -1.935  1.00 34.23 ? 79  PHE   A H    1 
ATOM   1146  H  HA   . PHE   A 1 80  ? 12.450  -1.835  -1.455  1.00 34.02 ? 79  PHE   A HA   1 
ATOM   1147  H  HB2  . PHE   A 1 80  ? 10.524  -2.028  -0.169  1.00 35.90 ? 79  PHE   A HB2  1 
ATOM   1148  H  HB3  . PHE   A 1 80  ? 11.079  -3.370  0.475   1.00 35.90 ? 79  PHE   A HB3  1 
ATOM   1149  H  HD1  . PHE   A 1 80  ? 11.425  0.117   0.557   1.00 33.44 ? 79  PHE   A HD1  1 
ATOM   1150  H  HD2  . PHE   A 1 80  ? 12.727  -3.286  2.211   1.00 29.42 ? 79  PHE   A HD2  1 
ATOM   1151  H  HE1  . PHE   A 1 80  ? 12.433  1.339   2.261   1.00 30.50 ? 79  PHE   A HE1  1 
ATOM   1152  H  HE2  . PHE   A 1 80  ? 13.791  -2.097  3.846   1.00 27.23 ? 79  PHE   A HE2  1 
ATOM   1153  H  HZ   . PHE   A 1 80  ? 13.625  0.237   3.899   1.00 29.88 ? 79  PHE   A HZ   1 
ATOM   1154  N  N    . LEU   A 1 81  ? 13.453  -4.669  -0.277  1.00 26.81 ? 80  LEU   A N    1 
ATOM   1155  C  CA   . LEU   A 1 81  ? 14.653  -5.313  0.258   1.00 30.37 ? 80  LEU   A CA   1 
ATOM   1156  C  C    . LEU   A 1 81  ? 15.800  -5.300  -0.747  1.00 23.52 ? 80  LEU   A C    1 
ATOM   1157  O  O    . LEU   A 1 81  ? 16.950  -5.024  -0.377  1.00 25.90 ? 80  LEU   A O    1 
ATOM   1158  C  CB   . LEU   A 1 81  ? 14.357  -6.744  0.711   1.00 34.08 ? 80  LEU   A CB   1 
ATOM   1159  C  CG   . LEU   A 1 81  ? 14.409  -6.975  2.215   1.00 41.19 ? 80  LEU   A CG   1 
ATOM   1160  C  CD1  . LEU   A 1 81  ? 13.903  -8.383  2.528   1.00 43.00 ? 80  LEU   A CD1  1 
ATOM   1161  C  CD2  . LEU   A 1 81  ? 15.810  -6.787  2.789   1.00 36.12 ? 80  LEU   A CD2  1 
ATOM   1162  H  H    . LEU   A 1 81  ? 12.752  -5.165  -0.314  1.00 32.18 ? 80  LEU   A H    1 
ATOM   1163  H  HA   . LEU   A 1 81  ? 14.930  -4.809  1.039   1.00 36.44 ? 80  LEU   A HA   1 
ATOM   1164  H  HB2  . LEU   A 1 81  ? 13.465  -6.980  0.412   1.00 40.89 ? 80  LEU   A HB2  1 
ATOM   1165  H  HB3  . LEU   A 1 81  ? 15.010  -7.334  0.304   1.00 40.89 ? 80  LEU   A HB3  1 
ATOM   1166  H  HG   . LEU   A 1 81  ? 13.842  -6.314  2.642   1.00 49.43 ? 80  LEU   A HG   1 
ATOM   1167  H  HD11 . LEU   A 1 81  ? 13.939  -8.526  3.487   1.00 51.60 ? 80  LEU   A HD11 1 
ATOM   1168  H  HD12 . LEU   A 1 81  ? 12.988  -8.467  2.215   1.00 51.60 ? 80  LEU   A HD12 1 
ATOM   1169  H  HD13 . LEU   A 1 81  ? 14.467  -9.029  2.076   1.00 51.60 ? 80  LEU   A HD13 1 
ATOM   1170  H  HD21 . LEU   A 1 81  ? 15.783  -6.944  3.746   1.00 43.34 ? 80  LEU   A HD21 1 
ATOM   1171  H  HD22 . LEU   A 1 81  ? 16.412  -7.419  2.367   1.00 43.34 ? 80  LEU   A HD22 1 
ATOM   1172  H  HD23 . LEU   A 1 81  ? 16.105  -5.880  2.611   1.00 43.34 ? 80  LEU   A HD23 1 
ATOM   1173  N  N    . GLY   A 1 82  ? 15.526  -5.575  -2.025  1.00 22.25 ? 81  GLY   A N    1 
ATOM   1174  C  CA   . GLY   A 1 82  ? 16.602  -5.562  -3.000  1.00 27.78 ? 81  GLY   A CA   1 
ATOM   1175  C  C    . GLY   A 1 82  ? 17.228  -4.185  -3.163  1.00 27.58 ? 81  GLY   A C    1 
ATOM   1176  O  O    . GLY   A 1 82  ? 18.445  -4.055  -3.327  1.00 25.87 ? 81  GLY   A O    1 
ATOM   1177  H  H    . GLY   A 1 82  ? 14.749  -5.766  -2.338  1.00 26.70 ? 81  GLY   A H    1 
ATOM   1178  H  HA2  . GLY   A 1 82  ? 17.295  -6.181  -2.721  1.00 33.34 ? 81  GLY   A HA2  1 
ATOM   1179  H  HA3  . GLY   A 1 82  ? 16.257  -5.844  -3.862  1.00 33.34 ? 81  GLY   A HA3  1 
ATOM   1180  N  N    . ARG   A 1 83  ? 16.403  -3.141  -3.133  1.00 24.56 ? 82  ARG   A N    1 
ATOM   1181  C  CA   . ARG   A 1 83  ? 16.930  -1.779  -3.215  1.00 24.15 ? 82  ARG   A CA   1 
ATOM   1182  C  C    . ARG   A 1 83  ? 17.726  -1.417  -1.969  1.00 22.63 ? 82  ARG   A C    1 
ATOM   1183  O  O    . ARG   A 1 83  ? 18.797  -0.803  -2.073  1.00 23.56 ? 82  ARG   A O    1 
ATOM   1184  C  CB   . ARG   A 1 83  ? 15.773  -0.805  -3.457  1.00 24.04 ? 82  ARG   A CB   1 
ATOM   1185  C  CG   . ARG   A 1 83  ? 15.277  -0.895  -4.915  1.00 29.15 ? 82  ARG   A CG   1 
ATOM   1186  C  CD   . ARG   A 1 83  ? 14.142  0.090   -5.247  1.00 31.42 ? 82  ARG   A CD   1 
ATOM   1187  N  NE   . ARG   A 1 83  ? 12.929  -0.087  -4.455  1.00 29.58 ? 82  ARG   A NE   1 
ATOM   1188  C  CZ   . ARG   A 1 83  ? 12.624  0.669   -3.412  1.00 26.23 ? 82  ARG   A CZ   1 
ATOM   1189  N  NH1  . ARG   A 1 83  ? 13.467  1.571   -2.956  1.00 26.30 ? 82  ARG   A NH1  1 
ATOM   1190  N  NH2  . ARG   A 1 83  ? 11.446  0.520   -2.815  1.00 28.08 ? 82  ARG   A NH2  1 
ATOM   1191  H  H    . ARG   A 1 83  ? 15.547  -3.192  -3.067  1.00 29.47 ? 82  ARG   A H    1 
ATOM   1192  H  HA   . ARG   A 1 83  ? 17.539  -1.707  -3.967  1.00 28.98 ? 82  ARG   A HA   1 
ATOM   1193  H  HB2  . ARG   A 1 83  ? 15.036  -1.026  -2.867  1.00 28.85 ? 82  ARG   A HB2  1 
ATOM   1194  H  HB3  . ARG   A 1 83  ? 16.073  0.102   -3.289  1.00 28.85 ? 82  ARG   A HB3  1 
ATOM   1195  H  HG2  . ARG   A 1 83  ? 16.018  -0.702  -5.510  1.00 34.99 ? 82  ARG   A HG2  1 
ATOM   1196  H  HG3  . ARG   A 1 83  ? 14.946  -1.792  -5.078  1.00 34.99 ? 82  ARG   A HG3  1 
ATOM   1197  H  HD2  . ARG   A 1 83  ? 14.462  0.992   -5.092  1.00 37.70 ? 82  ARG   A HD2  1 
ATOM   1198  H  HD3  . ARG   A 1 83  ? 13.900  -0.021  -6.179  1.00 37.70 ? 82  ARG   A HD3  1 
ATOM   1199  H  HE   . ARG   A 1 83  ? 12.384  -0.714  -4.677  1.00 35.50 ? 82  ARG   A HE   1 
ATOM   1200  H  HH11 . ARG   A 1 83  ? 14.231  1.677   -3.337  1.00 31.56 ? 82  ARG   A HH11 1 
ATOM   1201  H  HH12 . ARG   A 1 83  ? 13.254  2.054   -2.277  1.00 31.56 ? 82  ARG   A HH12 1 
ATOM   1202  H  HH21 . ARG   A 1 83  ? 10.886  -0.064  -3.107  1.00 33.69 ? 82  ARG   A HH21 1 
ATOM   1203  H  HH22 . ARG   A 1 83  ? 11.243  1.009   -2.137  1.00 33.69 ? 82  ARG   A HH22 1 
ATOM   1204  N  N    . TYR   A 1 84  ? 17.256  -1.850  -0.791  1.00 21.70 ? 83  TYR   A N    1 
ATOM   1205  C  CA   . TYR   A 1 84  ? 18.000  -1.615  0.446   1.00 20.57 ? 83  TYR   A CA   1 
ATOM   1206  C  C    . TYR   A 1 84  ? 19.354  -2.325  0.400   1.00 19.87 ? 83  TYR   A C    1 
ATOM   1207  O  O    . TYR   A 1 84  ? 20.398  -1.726  0.698   1.00 19.59 ? 83  TYR   A O    1 
ATOM   1208  C  CB   . TYR   A 1 84  ? 17.122  -2.044  1.643   1.00 22.00 ? 83  TYR   A CB   1 
ATOM   1209  C  CG   . TYR   A 1 84  ? 17.795  -2.209  2.981   1.00 21.73 ? 83  TYR   A CG   1 
ATOM   1210  C  CD1  . TYR   A 1 84  ? 18.777  -1.323  3.408   1.00 22.60 ? 83  TYR   A CD1  1 
ATOM   1211  C  CD2  . TYR   A 1 84  ? 17.406  -3.226  3.855   1.00 26.83 ? 83  TYR   A CD2  1 
ATOM   1212  C  CE1  . TYR   A 1 84  ? 19.381  -1.470  4.633   1.00 23.98 ? 83  TYR   A CE1  1 
ATOM   1213  C  CE2  . TYR   A 1 84  ? 18.003  -3.378  5.075   1.00 25.75 ? 83  TYR   A CE2  1 
ATOM   1214  C  CZ   . TYR   A 1 84  ? 18.986  -2.508  5.473   1.00 23.41 ? 83  TYR   A CZ   1 
ATOM   1215  O  OH   . TYR   A 1 84  ? 19.578  -2.647  6.709   1.00 31.62 ? 83  TYR   A OH   1 
ATOM   1216  H  H    . TYR   A 1 84  ? 16.517  -2.277  -0.685  1.00 26.04 ? 83  TYR   A H    1 
ATOM   1217  H  HA   . TYR   A 1 84  ? 18.195  -0.672  0.566   1.00 24.69 ? 83  TYR   A HA   1 
ATOM   1218  H  HB2  . TYR   A 1 84  ? 16.431  -1.374  1.759   1.00 26.40 ? 83  TYR   A HB2  1 
ATOM   1219  H  HB3  . TYR   A 1 84  ? 16.722  -2.900  1.425   1.00 26.40 ? 83  TYR   A HB3  1 
ATOM   1220  H  HD1  . TYR   A 1 84  ? 19.029  -0.619  2.856   1.00 27.12 ? 83  TYR   A HD1  1 
ATOM   1221  H  HD2  . TYR   A 1 84  ? 16.728  -3.811  3.603   1.00 32.19 ? 83  TYR   A HD2  1 
ATOM   1222  H  HE1  . TYR   A 1 84  ? 20.049  -0.880  4.900   1.00 28.78 ? 83  TYR   A HE1  1 
ATOM   1223  H  HE2  . TYR   A 1 84  ? 17.743  -4.071  5.637   1.00 30.90 ? 83  TYR   A HE2  1 
ATOM   1224  H  HH   . TYR   A 1 84  ? 19.459  -1.951  7.164   1.00 37.94 ? 83  TYR   A HH   1 
ATOM   1225  N  N    . MET   A 1 85  ? 19.375  -3.580  -0.042  1.00 23.88 ? 84  MET   A N    1 
ATOM   1226  C  CA   . MET   A 1 85  ? 20.658  -4.275  -0.111  1.00 22.83 ? 84  MET   A CA   1 
ATOM   1227  C  C    . MET   A 1 85  ? 21.592  -3.633  -1.137  1.00 19.08 ? 84  MET   A C    1 
ATOM   1228  O  O    . MET   A 1 85  ? 22.792  -3.480  -0.879  1.00 20.23 ? 84  MET   A O    1 
ATOM   1229  C  CB   . MET   A 1 85  ? 20.440  -5.751  -0.436  1.00 23.48 ? 84  MET   A CB   1 
ATOM   1230  C  CG   . MET   A 1 85  ? 19.758  -6.438  0.735   1.00 29.51 ? 84  MET   A CG   1 
ATOM   1231  S  SD   . MET   A 1 85  ? 20.878  -6.743  2.097   1.00 28.43 ? 84  MET   A SD   1 
ATOM   1232  C  CE   . MET   A 1 85  ? 20.237  -5.590  3.307   1.00 27.70 ? 84  MET   A CE   1 
ATOM   1233  H  H    . MET   A 1 85  ? 18.690  -4.034  -0.297  1.00 28.65 ? 84  MET   A H    1 
ATOM   1234  H  HA   . MET   A 1 85  ? 21.077  -4.221  0.762   1.00 27.40 ? 84  MET   A HA   1 
ATOM   1235  H  HB2  . MET   A 1 85  ? 19.875  -5.834  -1.220  1.00 28.18 ? 84  MET   A HB2  1 
ATOM   1236  H  HB3  . MET   A 1 85  ? 21.295  -6.181  -0.596  1.00 28.18 ? 84  MET   A HB3  1 
ATOM   1237  H  HG2  . MET   A 1 85  ? 19.038  -5.874  1.058   1.00 35.41 ? 84  MET   A HG2  1 
ATOM   1238  H  HG3  . MET   A 1 85  ? 19.404  -7.292  0.440   1.00 35.41 ? 84  MET   A HG3  1 
ATOM   1239  H  HE1  . MET   A 1 85  ? 20.744  -5.680  4.129   1.00 33.24 ? 84  MET   A HE1  1 
ATOM   1240  H  HE2  . MET   A 1 85  ? 20.326  -4.688  2.961   1.00 33.24 ? 84  MET   A HE2  1 
ATOM   1241  H  HE3  . MET   A 1 85  ? 19.302  -5.791  3.471   1.00 33.24 ? 84  MET   A HE3  1 
ATOM   1242  N  N    . SER   A 1 86  ? 21.074  -3.267  -2.318  1.00 22.74 ? 85  SER   A N    1 
ATOM   1243  C  CA   . SER   A 1 86  ? 21.921  -2.623  -3.330  1.00 23.44 ? 85  SER   A CA   1 
ATOM   1244  C  C    . SER   A 1 86  ? 22.540  -1.322  -2.817  1.00 19.85 ? 85  SER   A C    1 
ATOM   1245  O  O    . SER   A 1 86  ? 23.727  -1.056  -3.062  1.00 22.27 ? 85  SER   A O    1 
ATOM   1246  C  CB   . SER   A 1 86  ? 21.137  -2.343  -4.616  1.00 29.31 ? 85  SER   A CB   1 
ATOM   1247  O  OG   . SER   A 1 86  ? 20.502  -3.515  -5.080  1.00 42.00 ? 85  SER   A OG   1 
ATOM   1248  H  H    . SER   A 1 86  ? 20.255  -3.378  -2.554  1.00 27.28 ? 85  SER   A H    1 
ATOM   1249  H  HA   . SER   A 1 86  ? 22.636  -3.245  -3.539  1.00 28.13 ? 85  SER   A HA   1 
ATOM   1250  H  HB2  . SER   A 1 86  ? 20.463  -1.669  -4.435  1.00 35.17 ? 85  SER   A HB2  1 
ATOM   1251  H  HB3  . SER   A 1 86  ? 21.750  -2.024  -5.297  1.00 35.17 ? 85  SER   A HB3  1 
ATOM   1252  H  HG   . SER   A 1 86  ? 19.731  -3.574  -4.751  1.00 50.40 ? 85  SER   A HG   1 
ATOM   1253  N  N    . ALA   A 1 87  ? 21.749  -0.501  -2.107  1.00 19.95 ? 86  ALA   A N    1 
ATOM   1254  C  CA   . ALA   A 1 87  ? 22.293  0.718   -1.500  1.00 22.28 ? 86  ALA   A CA   1 
ATOM   1255  C  C    . ALA   A 1 87  ? 23.336  0.392   -0.421  1.00 17.80 ? 86  ALA   A C    1 
ATOM   1256  O  O    . ALA   A 1 87  ? 24.404  1.014   -0.386  1.00 20.10 ? 86  ALA   A O    1 
ATOM   1257  C  CB   . ALA   A 1 87  ? 21.163  1.559   -0.915  1.00 20.43 ? 86  ALA   A CB   1 
ATOM   1258  H  H    . ALA   A 1 87  ? 20.910  -0.626  -1.966  1.00 23.94 ? 86  ALA   A H    1 
ATOM   1259  H  HA   . ALA   A 1 87  ? 22.732  1.239   -2.190  1.00 26.74 ? 86  ALA   A HA   1 
ATOM   1260  H  HB1  . ALA   A 1 87  ? 21.545  2.295   -0.411  1.00 24.51 ? 86  ALA   A HB1  1 
ATOM   1261  H  HB2  . ALA   A 1 87  ? 20.617  1.903   -1.639  1.00 24.51 ? 86  ALA   A HB2  1 
ATOM   1262  H  HB3  . ALA   A 1 87  ? 20.624  1.003   -0.331  1.00 24.51 ? 86  ALA   A HB3  1 
ATOM   1263  N  N    . LEU   A 1 88  ? 23.054  -0.601  0.452   1.00 20.02 ? 87  LEU   A N    1 
ATOM   1264  C  CA   . LEU   A 1 88  ? 23.982  -0.925  1.539   1.00 22.70 ? 87  LEU   A CA   1 
ATOM   1265  C  C    . LEU   A 1 88  ? 25.337  -1.340  0.988   1.00 18.92 ? 87  LEU   A C    1 
ATOM   1266  O  O    . LEU   A 1 88  ? 26.378  -1.005  1.555   1.00 20.38 ? 87  LEU   A O    1 
ATOM   1267  C  CB   . LEU   A 1 88  ? 23.422  -2.046  2.417   1.00 18.73 ? 87  LEU   A CB   1 
ATOM   1268  C  CG   . LEU   A 1 88  ? 24.253  -2.451  3.632   1.00 23.97 ? 87  LEU   A CG   1 
ATOM   1269  C  CD1  . LEU   A 1 88  ? 24.461  -1.300  4.581   1.00 22.96 ? 87  LEU   A CD1  1 
ATOM   1270  C  CD2  . LEU   A 1 88  ? 23.556  -3.637  4.321   1.00 29.25 ? 87  LEU   A CD2  1 
ATOM   1271  H  H    . LEU   A 1 88  ? 22.346  -1.088  0.431   1.00 24.02 ? 87  LEU   A H    1 
ATOM   1272  H  HA   . LEU   A 1 88  ? 24.088  -0.135  2.091   1.00 27.24 ? 87  LEU   A HA   1 
ATOM   1273  H  HB2  . LEU   A 1 88  ? 22.556  -1.761  2.749   1.00 22.48 ? 87  LEU   A HB2  1 
ATOM   1274  H  HB3  . LEU   A 1 88  ? 23.322  -2.837  1.865   1.00 22.48 ? 87  LEU   A HB3  1 
ATOM   1275  H  HG   . LEU   A 1 88  ? 25.142  -2.720  3.350   1.00 28.76 ? 87  LEU   A HG   1 
ATOM   1276  H  HD11 . LEU   A 1 88  ? 24.517  -1.643  5.486   1.00 27.55 ? 87  LEU   A HD11 1 
ATOM   1277  H  HD12 . LEU   A 1 88  ? 25.286  -0.844  4.349   1.00 27.55 ? 87  LEU   A HD12 1 
ATOM   1278  H  HD13 . LEU   A 1 88  ? 23.713  -0.688  4.504   1.00 27.55 ? 87  LEU   A HD13 1 
ATOM   1279  H  HD21 . LEU   A 1 88  ? 24.088  -3.917  5.082   1.00 35.11 ? 87  LEU   A HD21 1 
ATOM   1280  H  HD22 . LEU   A 1 88  ? 22.676  -3.357  4.618   1.00 35.11 ? 87  LEU   A HD22 1 
ATOM   1281  H  HD23 . LEU   A 1 88  ? 23.474  -4.367  3.688   1.00 35.11 ? 87  LEU   A HD23 1 
ATOM   1282  N  N    . ASN   A 1 89  ? 25.337  -2.058  -0.131  1.00 21.12 ? 88  ASN   A N    1 
ATOM   1283  C  CA   . ASN   A 1 89  ? 26.594  -2.468  -0.747  1.00 22.60 ? 88  ASN   A CA   1 
ATOM   1284  C  C    . ASN   A 1 89  ? 27.493  -1.272  -1.045  1.00 21.82 ? 88  ASN   A C    1 
ATOM   1285  O  O    . ASN   A 1 89  ? 28.716  -1.390  -1.004  1.00 25.79 ? 88  ASN   A O    1 
ATOM   1286  C  CB   . ASN   A 1 89  ? 26.283  -3.299  -1.994  1.00 25.71 ? 88  ASN   A CB   1 
ATOM   1287  C  CG   . ASN   A 1 89  ? 27.454  -4.129  -2.424  1.00 30.10 ? 88  ASN   A CG   1 
ATOM   1288  O  OD1  . ASN   A 1 89  ? 28.116  -4.751  -1.596  1.00 30.90 ? 88  ASN   A OD1  1 
ATOM   1289  N  ND2  . ASN   A 1 89  ? 27.692  -4.187  -3.725  1.00 35.15 ? 88  ASN   A ND2  1 
ATOM   1290  H  H    . ASN   A 1 89  ? 24.632  -2.317  -0.549  1.00 25.35 ? 88  ASN   A H    1 
ATOM   1291  H  HA   . ASN   A 1 89  ? 27.100  -3.033  -0.142  1.00 27.12 ? 88  ASN   A HA   1 
ATOM   1292  H  HB2  . ASN   A 1 89  ? 25.543  -3.897  -1.802  1.00 30.85 ? 88  ASN   A HB2  1 
ATOM   1293  H  HB3  . ASN   A 1 89  ? 26.049  -2.704  -2.723  1.00 30.85 ? 88  ASN   A HB3  1 
ATOM   1294  H  HD21 . ASN   A 1 89  ? 27.184  -3.762  -4.274  1.00 42.18 ? 88  ASN   A HD21 1 
ATOM   1295  H  HD22 . ASN   A 1 89  ? 28.353  -4.650  -4.021  1.00 42.18 ? 88  ASN   A HD22 1 
ATOM   1296  N  N    . HIS   A 1 90  ? 26.914  -0.104  -1.282  1.00 19.22 ? 89  HIS   A N    1 
ATOM   1297  C  CA   . HIS   A 1 90  ? 27.678  1.130   -1.421  1.00 19.88 ? 89  HIS   A CA   1 
ATOM   1298  C  C    . HIS   A 1 90  ? 27.867  1.870   -0.093  1.00 19.12 ? 89  HIS   A C    1 
ATOM   1299  O  O    . HIS   A 1 90  ? 28.980  2.331   0.209   1.00 21.43 ? 89  HIS   A O    1 
ATOM   1300  C  CB   . HIS   A 1 90  ? 26.999  2.078   -2.422  1.00 21.66 ? 89  HIS   A CB   1 
ATOM   1301  C  CG   . HIS   A 1 90  ? 27.029  1.608   -3.851  1.00 24.76 ? 89  HIS   A CG   1 
ATOM   1302  N  ND1  . HIS   A 1 90  ? 25.994  0.914   -4.447  1.00 30.64 ? 89  HIS   A ND1  1 
ATOM   1303  C  CD2  . HIS   A 1 90  ? 27.965  1.783   -4.809  1.00 28.23 ? 89  HIS   A CD2  1 
ATOM   1304  C  CE1  . HIS   A 1 90  ? 26.308  0.659   -5.710  1.00 24.03 ? 89  HIS   A CE1  1 
ATOM   1305  N  NE2  . HIS   A 1 90  ? 27.498  1.178   -5.952  1.00 31.39 ? 89  HIS   A NE2  1 
ATOM   1306  H  H    . HIS   A 1 90  ? 26.066  0.005   -1.368  1.00 23.07 ? 89  HIS   A H    1 
ATOM   1307  H  HA   . HIS   A 1 90  ? 28.552  0.884   -1.763  1.00 23.86 ? 89  HIS   A HA   1 
ATOM   1308  H  HB2  . HIS   A 1 90  ? 26.069  2.180   -2.168  1.00 25.99 ? 89  HIS   A HB2  1 
ATOM   1309  H  HB3  . HIS   A 1 90  ? 27.449  2.936   -2.388  1.00 25.99 ? 89  HIS   A HB3  1 
ATOM   1310  H  HD1  . HIS   A 1 90  ? 25.262  0.684   -4.059  1.00 36.77 ? 89  HIS   A HD1  1 
ATOM   1311  H  HD2  . HIS   A 1 90  ? 28.775  2.230   -4.713  1.00 33.88 ? 89  HIS   A HD2  1 
ATOM   1312  H  HE1  . HIS   A 1 90  ? 25.781  0.195   -6.320  1.00 28.84 ? 89  HIS   A HE1  1 
ATOM   1313  N  N    . THR   A 1 91  ? 26.794  2.058   0.692   1.00 18.59 ? 90  THR   A N    1 
ATOM   1314  C  CA   . THR   A 1 91  ? 26.969  2.909   1.873   1.00 21.74 ? 90  THR   A CA   1 
ATOM   1315  C  C    . THR   A 1 91  ? 27.907  2.279   2.908   1.00 21.24 ? 90  THR   A C    1 
ATOM   1316  O  O    . THR   A 1 91  ? 28.516  3.006   3.706   1.00 17.50 ? 90  THR   A O    1 
ATOM   1317  C  CB   . THR   A 1 91  ? 25.634  3.247   2.554   1.00 18.22 ? 90  THR   A CB   1 
ATOM   1318  O  OG1  . THR   A 1 91  ? 25.068  2.052   3.090   1.00 20.72 ? 90  THR   A OG1  1 
ATOM   1319  C  CG2  . THR   A 1 91  ? 24.621  3.938   1.606   1.00 20.93 ? 90  THR   A CG2  1 
ATOM   1320  H  H    . THR   A 1 91  ? 26.010  1.726   0.569   1.00 22.31 ? 90  THR   A H    1 
ATOM   1321  H  HA   . THR   A 1 91  ? 27.348  3.745   1.560   1.00 26.09 ? 90  THR   A HA   1 
ATOM   1322  H  HB   . THR   A 1 91  ? 25.808  3.884   3.264   1.00 21.87 ? 90  THR   A HB   1 
ATOM   1323  H  HG1  . THR   A 1 91  ? 24.324  2.220   3.442   1.00 24.87 ? 90  THR   A HG1  1 
ATOM   1324  H  HG21 . THR   A 1 91  ? 24.214  4.697   2.052   1.00 25.12 ? 90  THR   A HG21 1 
ATOM   1325  H  HG22 . THR   A 1 91  ? 25.073  4.248   0.806   1.00 25.12 ? 90  THR   A HG22 1 
ATOM   1326  H  HG23 . THR   A 1 91  ? 23.925  3.312   1.352   1.00 25.12 ? 90  THR   A HG23 1 
ATOM   1327  N  N    . LYS   A 1 92  ? 28.061  0.955   2.909   1.00 21.27 ? 91  LYS   A N    1 
ATOM   1328  C  CA   . LYS   A 1 92  ? 29.018  0.340   3.824   1.00 20.58 ? 91  LYS   A CA   1 
ATOM   1329  C  C    . LYS   A 1 92  ? 30.452  0.755   3.514   1.00 23.68 ? 91  LYS   A C    1 
ATOM   1330  O  O    . LYS   A 1 92  ? 31.330  0.595   4.369   1.00 24.83 ? 91  LYS   A O    1 
ATOM   1331  C  CB   . LYS   A 1 92  ? 28.922  -1.187  3.786   1.00 22.56 ? 91  LYS   A CB   1 
ATOM   1332  C  CG   . LYS   A 1 92  ? 29.437  -1.829  2.520   1.00 25.51 ? 91  LYS   A CG   1 
ATOM   1333  C  CD   . LYS   A 1 92  ? 29.017  -3.293  2.406   1.00 30.26 ? 91  LYS   A CD   1 
ATOM   1334  C  CE   . LYS   A 1 92  ? 29.836  -4.013  1.316   1.00 31.85 ? 91  LYS   A CE   1 
ATOM   1335  N  NZ   . LYS   A 1 92  ? 29.467  -5.454  1.153   1.00 28.91 ? 91  LYS   A NZ   1 
ATOM   1336  H  H    . LYS   A 1 92  ? 27.635  0.405   2.404   1.00 25.53 ? 91  LYS   A H    1 
ATOM   1337  H  HA   . LYS   A 1 92  ? 28.790  0.627   4.722   1.00 24.70 ? 91  LYS   A HA   1 
ATOM   1338  H  HB2  . LYS   A 1 92  ? 29.440  -1.545  4.524   1.00 27.08 ? 91  LYS   A HB2  1 
ATOM   1339  H  HB3  . LYS   A 1 92  ? 27.990  -1.438  3.881   1.00 27.08 ? 91  LYS   A HB3  1 
ATOM   1340  H  HG2  . LYS   A 1 92  ? 29.082  -1.352  1.754   1.00 30.61 ? 91  LYS   A HG2  1 
ATOM   1341  H  HG3  . LYS   A 1 92  ? 30.406  -1.791  2.515   1.00 30.61 ? 91  LYS   A HG3  1 
ATOM   1342  H  HD2  . LYS   A 1 92  ? 29.169  -3.741  3.253   1.00 36.31 ? 91  LYS   A HD2  1 
ATOM   1343  H  HD3  . LYS   A 1 92  ? 28.077  -3.343  2.168   1.00 36.31 ? 91  LYS   A HD3  1 
ATOM   1344  H  HE2  . LYS   A 1 92  ? 29.687  -3.570  0.466   1.00 38.22 ? 91  LYS   A HE2  1 
ATOM   1345  H  HE3  . LYS   A 1 92  ? 30.777  -3.972  1.551   1.00 38.22 ? 91  LYS   A HE3  1 
ATOM   1346  H  HZ1  . LYS   A 1 92  ? 30.036  -5.853  0.597   1.00 34.69 ? 91  LYS   A HZ1  1 
ATOM   1347  H  HZ2  . LYS   A 1 92  ? 29.496  -5.867  1.941   1.00 34.69 ? 91  LYS   A HZ2  1 
ATOM   1348  H  HZ3  . LYS   A 1 92  ? 28.644  -5.522  0.821   1.00 34.69 ? 91  LYS   A HZ3  1 
ATOM   1349  N  N    . LYS   A 1 93  ? 30.713  1.255   2.310   1.00 21.88 ? 92  LYS   A N    1 
ATOM   1350  C  CA   . LYS   A 1 93  ? 32.034  1.731   1.910   1.00 24.55 ? 92  LYS   A CA   1 
ATOM   1351  C  C    . LYS   A 1 93  ? 32.219  3.232   2.100   1.00 24.50 ? 92  LYS   A C    1 
ATOM   1352  O  O    . LYS   A 1 93  ? 33.352  3.709   2.006   1.00 26.05 ? 92  LYS   A O    1 
ATOM   1353  C  CB   . LYS   A 1 93  ? 32.302  1.366   0.442   1.00 24.12 ? 92  LYS   A CB   1 
ATOM   1354  C  CG   . LYS   A 1 93  ? 32.119  -0.125  0.154   1.00 27.54 ? 92  LYS   A CG   1 
ATOM   1355  C  CD   . LYS   A 1 93  ? 32.349  -0.484  -1.307  1.00 34.44 ? 92  LYS   A CD   1 
ATOM   1356  C  CE   . LYS   A 1 93  ? 31.969  -1.939  -1.565  1.00 42.12 ? 92  LYS   A CE   1 
ATOM   1357  N  NZ   . LYS   A 1 93  ? 32.500  -2.430  -2.862  1.00 51.97 ? 92  LYS   A NZ   1 
ATOM   1358  H  H    . LYS   A 1 93  ? 30.125  1.331   1.687   1.00 26.25 ? 92  LYS   A H    1 
ATOM   1359  H  HA   . LYS   A 1 93  ? 32.700  1.286   2.457   1.00 29.46 ? 92  LYS   A HA   1 
ATOM   1360  H  HB2  . LYS   A 1 93  ? 31.685  1.858   -0.122  1.00 28.94 ? 92  LYS   A HB2  1 
ATOM   1361  H  HB3  . LYS   A 1 93  ? 33.216  1.604   0.220   1.00 28.94 ? 92  LYS   A HB3  1 
ATOM   1362  H  HG2  . LYS   A 1 93  ? 32.752  -0.629  0.688   1.00 33.05 ? 92  LYS   A HG2  1 
ATOM   1363  H  HG3  . LYS   A 1 93  ? 31.212  -0.381  0.384   1.00 33.05 ? 92  LYS   A HG3  1 
ATOM   1364  H  HD2  . LYS   A 1 93  ? 31.801  0.083   -1.872  1.00 41.33 ? 92  LYS   A HD2  1 
ATOM   1365  H  HD3  . LYS   A 1 93  ? 33.286  -0.366  -1.527  1.00 41.33 ? 92  LYS   A HD3  1 
ATOM   1366  H  HE2  . LYS   A 1 93  ? 32.334  -2.494  -0.858  1.00 50.54 ? 92  LYS   A HE2  1 
ATOM   1367  H  HE3  . LYS   A 1 93  ? 31.003  -2.018  -1.583  1.00 50.54 ? 92  LYS   A HE3  1 
ATOM   1368  H  HZ1  . LYS   A 1 93  ? 32.123  -3.209  -3.070  1.00 62.36 ? 92  LYS   A HZ1  1 
ATOM   1369  H  HZ2  . LYS   A 1 93  ? 32.322  -1.842  -3.506  1.00 62.36 ? 92  LYS   A HZ2  1 
ATOM   1370  H  HZ3  . LYS   A 1 93  ? 33.382  -2.540  -2.808  1.00 62.36 ? 92  LYS   A HZ3  1 
ATOM   1371  N  N    . TRP   A 1 94  ? 31.150  3.987   2.371   1.00 21.17 ? 93  TRP   A N    1 
ATOM   1372  C  CA   . TRP   A 1 94  ? 31.310  5.385   2.747   1.00 20.77 ? 93  TRP   A CA   1 
ATOM   1373  C  C    . TRP   A 1 94  ? 32.032  5.512   4.087   1.00 21.69 ? 93  TRP   A C    1 
ATOM   1374  O  O    . TRP   A 1 94  ? 32.095  4.571   4.892   1.00 23.89 ? 93  TRP   A O    1 
ATOM   1375  C  CB   . TRP   A 1 94  ? 29.950  6.089   2.830   1.00 18.51 ? 93  TRP   A CB   1 
ATOM   1376  C  CG   . TRP   A 1 94  ? 29.233  6.242   1.502   1.00 17.24 ? 93  TRP   A CG   1 
ATOM   1377  C  CD1  . TRP   A 1 94  ? 29.739  5.997   0.237   1.00 21.77 ? 93  TRP   A CD1  1 
ATOM   1378  C  CD2  . TRP   A 1 94  ? 27.888  6.689   1.308   1.00 18.60 ? 93  TRP   A CD2  1 
ATOM   1379  N  NE1  . TRP   A 1 94  ? 28.774  6.269   -0.722  1.00 20.66 ? 93  TRP   A NE1  1 
ATOM   1380  C  CE2  . TRP   A 1 94  ? 27.634  6.693   -0.091  1.00 19.37 ? 93  TRP   A CE2  1 
ATOM   1381  C  CE3  . TRP   A 1 94  ? 26.872  7.081   2.162   1.00 18.23 ? 93  TRP   A CE3  1 
ATOM   1382  C  CZ2  . TRP   A 1 94  ? 26.414  7.081   -0.623  1.00 19.36 ? 93  TRP   A CZ2  1 
ATOM   1383  C  CZ3  . TRP   A 1 94  ? 25.651  7.471   1.622   1.00 17.81 ? 93  TRP   A CZ3  1 
ATOM   1384  C  CH2  . TRP   A 1 94  ? 25.436  7.454   0.240   1.00 16.34 ? 93  TRP   A CH2  1 
ATOM   1385  H  H    . TRP   A 1 94  ? 30.335  3.714   2.344   1.00 25.41 ? 93  TRP   A H    1 
ATOM   1386  H  HA   . TRP   A 1 94  ? 31.843  5.827   2.068   1.00 24.92 ? 93  TRP   A HA   1 
ATOM   1387  H  HB2  . TRP   A 1 94  ? 29.373  5.576   3.417   1.00 22.21 ? 93  TRP   A HB2  1 
ATOM   1388  H  HB3  . TRP   A 1 94  ? 30.085  6.978   3.193   1.00 22.21 ? 93  TRP   A HB3  1 
ATOM   1389  H  HD1  . TRP   A 1 94  ? 30.599  5.694   0.057   1.00 26.12 ? 93  TRP   A HD1  1 
ATOM   1390  H  HE1  . TRP   A 1 94  ? 28.875  6.185   -1.572  1.00 24.79 ? 93  TRP   A HE1  1 
ATOM   1391  H  HE3  . TRP   A 1 94  ? 27.004  7.083   3.082   1.00 21.87 ? 93  TRP   A HE3  1 
ATOM   1392  H  HZ2  . TRP   A 1 94  ? 26.271  7.086   -1.542  1.00 23.23 ? 93  TRP   A HZ2  1 
ATOM   1393  H  HZ3  . TRP   A 1 94  ? 24.967  7.748   2.188   1.00 21.37 ? 93  TRP   A HZ3  1 
ATOM   1394  H  HH2  . TRP   A 1 94  ? 24.604  7.703   -0.095  1.00 19.61 ? 93  TRP   A HH2  1 
ATOM   1395  N  N    . LYS   A 1 95  ? 32.584  6.693   4.328   1.00 20.93 ? 94  LYS   A N    1 
ATOM   1396  C  CA   . LYS   A 1 95  ? 33.157  7.029   5.627   1.00 19.41 ? 94  LYS   A CA   1 
ATOM   1397  C  C    . LYS   A 1 95  ? 32.239  7.990   6.366   1.00 20.74 ? 94  LYS   A C    1 
ATOM   1398  O  O    . LYS   A 1 95  ? 31.656  8.908   5.772   1.00 19.66 ? 94  LYS   A O    1 
ATOM   1399  C  CB   . LYS   A 1 95  ? 34.524  7.691   5.526   1.00 20.13 ? 94  LYS   A CB   1 
ATOM   1400  C  CG   . LYS   A 1 95  ? 35.641  6.816   4.929   1.00 32.46 ? 94  LYS   A CG   1 
ATOM   1401  C  CD   . LYS   A 1 95  ? 35.297  5.343   4.939   1.00 42.36 ? 94  LYS   A CD   1 
ATOM   1402  C  CE   . LYS   A 1 95  ? 36.513  4.505   4.575   1.00 53.31 ? 94  LYS   A CE   1 
ATOM   1403  N  NZ   . LYS   A 1 95  ? 37.261  4.076   5.793   1.00 67.90 ? 94  LYS   A NZ   1 
ATOM   1404  H  H    . LYS   A 1 95  ? 32.639  7.326   3.749   1.00 25.12 ? 94  LYS   A H    1 
ATOM   1405  H  HA   . LYS   A 1 95  ? 33.257  6.201   6.121   1.00 23.29 ? 94  LYS   A HA   1 
ATOM   1406  H  HB2  . LYS   A 1 95  ? 34.441  8.477   4.963   1.00 24.16 ? 94  LYS   A HB2  1 
ATOM   1407  H  HB3  . LYS   A 1 95  ? 34.804  7.949   6.417   1.00 24.16 ? 94  LYS   A HB3  1 
ATOM   1408  H  HG2  . LYS   A 1 95  ? 35.794  7.082   4.009   1.00 38.95 ? 94  LYS   A HG2  1 
ATOM   1409  H  HG3  . LYS   A 1 95  ? 36.451  6.938   5.449   1.00 38.95 ? 94  LYS   A HG3  1 
ATOM   1410  H  HD2  . LYS   A 1 95  ? 34.998  5.086   5.825   1.00 50.83 ? 94  LYS   A HD2  1 
ATOM   1411  H  HD3  . LYS   A 1 95  ? 34.597  5.170   4.289   1.00 50.83 ? 94  LYS   A HD3  1 
ATOM   1412  H  HE2  . LYS   A 1 95  ? 36.225  3.712   4.097   1.00 63.97 ? 94  LYS   A HE2  1 
ATOM   1413  H  HE3  . LYS   A 1 95  ? 37.110  5.029   4.018   1.00 63.97 ? 94  LYS   A HE3  1 
ATOM   1414  H  HZ1  . LYS   A 1 95  ? 37.972  3.594   5.559   1.00 81.48 ? 94  LYS   A HZ1  1 
ATOM   1415  H  HZ2  . LYS   A 1 95  ? 37.534  4.789   6.250   1.00 81.48 ? 94  LYS   A HZ2  1 
ATOM   1416  H  HZ3  . LYS   A 1 95  ? 36.736  3.582   6.315   1.00 81.48 ? 94  LYS   A HZ3  1 
ATOM   1417  N  N    . TYR   A 1 96  ? 32.207  7.840   7.693   1.00 20.35 ? 95  TYR   A N    1 
ATOM   1418  C  CA   . TYR   A 1 96  ? 31.297  8.580   8.553   1.00 19.75 ? 95  TYR   A CA   1 
ATOM   1419  C  C    . TYR   A 1 96  ? 32.060  9.322   9.650   1.00 20.00 ? 95  TYR   A C    1 
ATOM   1420  O  O    . TYR   A 1 96  ? 32.054  8.914   10.832  1.00 23.14 ? 95  TYR   A O    1 
ATOM   1421  C  CB   . TYR   A 1 96  ? 30.281  7.594   9.118   1.00 18.98 ? 95  TYR   A CB   1 
ATOM   1422  C  CG   . TYR   A 1 96  ? 29.464  6.913   8.059   1.00 18.13 ? 95  TYR   A CG   1 
ATOM   1423  C  CD1  . TYR   A 1 96  ? 28.357  7.529   7.501   1.00 18.35 ? 95  TYR   A CD1  1 
ATOM   1424  C  CD2  . TYR   A 1 96  ? 29.849  5.674   7.539   1.00 23.16 ? 95  TYR   A CD2  1 
ATOM   1425  C  CE1  . TYR   A 1 96  ? 27.617  6.928   6.514   1.00 16.58 ? 95  TYR   A CE1  1 
ATOM   1426  C  CE2  . TYR   A 1 96  ? 29.103  5.047   6.564   1.00 20.86 ? 95  TYR   A CE2  1 
ATOM   1427  C  CZ   . TYR   A 1 96  ? 27.987  5.682   6.043   1.00 20.40 ? 95  TYR   A CZ   1 
ATOM   1428  O  OH   . TYR   A 1 96  ? 27.262  5.087   5.024   1.00 21.26 ? 95  TYR   A OH   1 
ATOM   1429  H  H    . TYR   A 1 96  ? 32.718  7.299   8.124   1.00 24.41 ? 95  TYR   A H    1 
ATOM   1430  H  HA   . TYR   A 1 96  ? 30.854  9.281   8.049   1.00 23.70 ? 95  TYR   A HA   1 
ATOM   1431  H  HB2  . TYR   A 1 96  ? 30.752  6.909   9.618   1.00 22.77 ? 95  TYR   A HB2  1 
ATOM   1432  H  HB3  . TYR   A 1 96  ? 29.672  8.072   9.703   1.00 22.77 ? 95  TYR   A HB3  1 
ATOM   1433  H  HD1  . TYR   A 1 96  ? 28.108  8.373   7.802   1.00 22.02 ? 95  TYR   A HD1  1 
ATOM   1434  H  HD2  . TYR   A 1 96  ? 30.622  5.266   7.856   1.00 27.80 ? 95  TYR   A HD2  1 
ATOM   1435  H  HE1  . TYR   A 1 96  ? 26.869  7.356   6.164   1.00 19.89 ? 95  TYR   A HE1  1 
ATOM   1436  H  HE2  . TYR   A 1 96  ? 29.347  4.203   6.259   1.00 25.04 ? 95  TYR   A HE2  1 
ATOM   1437  H  HH   . TYR   A 1 96  ? 27.475  4.277   4.954   1.00 25.51 ? 95  TYR   A HH   1 
ATOM   1438  N  N    . PRO   A 1 97  ? 32.706  10.426  9.315   1.00 21.01 ? 96  PRO   A N    1 
ATOM   1439  C  CA   . PRO   A 1 97  ? 33.472  11.143  10.339  1.00 23.72 ? 96  PRO   A CA   1 
ATOM   1440  C  C    . PRO   A 1 97  ? 32.542  11.753  11.359  1.00 23.25 ? 96  PRO   A C    1 
ATOM   1441  O  O    . PRO   A 1 97  ? 31.409  12.135  11.046  1.00 23.75 ? 96  PRO   A O    1 
ATOM   1442  C  CB   . PRO   A 1 97  ? 34.207  12.226  9.555   1.00 25.05 ? 96  PRO   A CB   1 
ATOM   1443  C  CG   . PRO   A 1 97  ? 33.402  12.422  8.307   1.00 25.82 ? 96  PRO   A CG   1 
ATOM   1444  C  CD   . PRO   A 1 97  ? 32.818  11.065  7.984   1.00 20.91 ? 96  PRO   A CD   1 
ATOM   1445  H  HA   . PRO   A 1 97  ? 34.119  10.561  10.766  1.00 28.46 ? 96  PRO   A HA   1 
ATOM   1446  H  HB2  . PRO   A 1 97  ? 34.243  13.043  10.077  1.00 30.05 ? 96  PRO   A HB2  1 
ATOM   1447  H  HB3  . PRO   A 1 97  ? 35.106  11.928  9.344   1.00 30.05 ? 96  PRO   A HB3  1 
ATOM   1448  H  HG2  . PRO   A 1 97  ? 32.699  13.071  8.468   1.00 30.98 ? 96  PRO   A HG2  1 
ATOM   1449  H  HG3  . PRO   A 1 97  ? 33.978  12.729  7.590   1.00 30.98 ? 96  PRO   A HG3  1 
ATOM   1450  H  HD2  . PRO   A 1 97  ? 31.947  11.154  7.568   1.00 25.09 ? 96  PRO   A HD2  1 
ATOM   1451  H  HD3  . PRO   A 1 97  ? 33.413  10.561  7.407   1.00 25.09 ? 96  PRO   A HD3  1 
ATOM   1452  N  N    . GLN   A 1 98  ? 33.021  11.798  12.608  1.00 24.83 ? 97  GLN   A N    1 
ATOM   1453  C  CA   . GLN   A 1 98  ? 32.370  12.535  13.676  1.00 24.75 ? 97  GLN   A CA   1 
ATOM   1454  C  C    . GLN   A 1 98  ? 32.778  13.998  13.659  1.00 26.35 ? 97  GLN   A C    1 
ATOM   1455  O  O    . GLN   A 1 98  ? 33.970  14.308  13.582  1.00 24.98 ? 97  GLN   A O    1 
ATOM   1456  C  CB   . GLN   A 1 98  ? 32.741  11.920  15.034  1.00 28.83 ? 97  GLN   A CB   1 
ATOM   1457  C  CG   . GLN   A 1 98  ? 32.211  10.498  15.207  1.00 33.40 ? 97  GLN   A CG   1 
ATOM   1458  C  CD   . GLN   A 1 98  ? 30.730  10.480  15.436  1.00 34.65 ? 97  GLN   A CD   1 
ATOM   1459  O  OE1  . GLN   A 1 98  ? 29.998  9.761   14.767  1.00 35.78 ? 97  GLN   A OE1  1 
ATOM   1460  N  NE2  . GLN   A 1 98  ? 30.282  11.208  16.446  1.00 28.77 ? 97  GLN   A NE2  1 
ATOM   1461  H  H    . GLN   A 1 98  ? 33.739  11.397  12.861  1.00 29.80 ? 97  GLN   A H    1 
ATOM   1462  H  HA   . GLN   A 1 98  ? 31.409  12.489  13.547  1.00 29.70 ? 97  GLN   A HA   1 
ATOM   1463  H  HB2  . GLN   A 1 98  ? 33.707  11.891  15.114  1.00 34.60 ? 97  GLN   A HB2  1 
ATOM   1464  H  HB3  . GLN   A 1 98  ? 32.365  12.467  15.741  1.00 34.60 ? 97  GLN   A HB3  1 
ATOM   1465  H  HG2  . GLN   A 1 98  ? 32.401  9.986   14.405  1.00 40.08 ? 97  GLN   A HG2  1 
ATOM   1466  H  HG3  . GLN   A 1 98  ? 32.642  10.087  15.972  1.00 40.08 ? 97  GLN   A HG3  1 
ATOM   1467  H  HE21 . GLN   A 1 98  ? 30.834  11.658  16.929  1.00 34.52 ? 97  GLN   A HE21 1 
ATOM   1468  H  HE22 . GLN   A 1 98  ? 29.440  11.232  16.620  1.00 34.52 ? 97  GLN   A HE22 1 
ATOM   1469  N  N    . VAL   A 1 99  ? 31.799  14.891  13.769  1.00 22.19 ? 98  VAL   A N    1 
ATOM   1470  C  CA   . VAL   A 1 99  ? 32.020  16.333  13.858  1.00 24.23 ? 98  VAL   A CA   1 
ATOM   1471  C  C    . VAL   A 1 99  ? 31.332  16.796  15.141  1.00 34.98 ? 98  VAL   A C    1 
ATOM   1472  O  O    . VAL   A 1 99  ? 30.098  16.901  15.197  1.00 29.82 ? 98  VAL   A O    1 
ATOM   1473  C  CB   . VAL   A 1 99  ? 31.468  17.065  12.633  1.00 33.25 ? 98  VAL   A CB   1 
ATOM   1474  C  CG1  . VAL   A 1 99  ? 31.824  18.537  12.679  1.00 40.14 ? 98  VAL   A CG1  1 
ATOM   1475  C  CG2  . VAL   A 1 99  ? 31.984  16.404  11.331  1.00 29.46 ? 98  VAL   A CG2  1 
ATOM   1476  H  H    . VAL   A 1 99  ? 30.966  14.678  13.795  1.00 26.63 ? 98  VAL   A H    1 
ATOM   1477  H  HA   . VAL   A 1 99  ? 32.969  16.527  13.924  1.00 29.07 ? 98  VAL   A HA   1 
ATOM   1478  H  HB   . VAL   A 1 99  ? 30.500  17.000  12.637  1.00 39.89 ? 98  VAL   A HB   1 
ATOM   1479  H  HG11 . VAL   A 1 99  ? 31.743  18.910  11.787  1.00 48.17 ? 98  VAL   A HG11 1 
ATOM   1480  H  HG12 . VAL   A 1 99  ? 31.216  18.990  13.284  1.00 48.17 ? 98  VAL   A HG12 1 
ATOM   1481  H  HG13 . VAL   A 1 99  ? 32.736  18.632  12.996  1.00 48.17 ? 98  VAL   A HG13 1 
ATOM   1482  H  HG21 . VAL   A 1 99  ? 31.871  17.026  10.595  1.00 35.35 ? 98  VAL   A HG21 1 
ATOM   1483  H  HG22 . VAL   A 1 99  ? 32.923  16.187  11.438  1.00 35.35 ? 98  VAL   A HG22 1 
ATOM   1484  H  HG23 . VAL   A 1 99  ? 31.474  15.596  11.163  1.00 35.35 ? 98  VAL   A HG23 1 
ATOM   1485  N  N    . ASN   A 1 100 ? 32.126  17.098  16.167  1.00 30.67 ? 99  ASN   A N    1 
ATOM   1486  C  CA   . ASN   A 1 100 ? 31.581  17.543  17.448  1.00 36.05 ? 99  ASN   A CA   1 
ATOM   1487  C  C    . ASN   A 1 100 ? 30.540  16.555  17.964  1.00 27.70 ? 99  ASN   A C    1 
ATOM   1488  O  O    . ASN   A 1 100 ? 29.510  16.940  18.531  1.00 33.15 ? 99  ASN   A O    1 
ATOM   1489  C  CB   . ASN   A 1 100 ? 30.965  18.935  17.330  1.00 38.12 ? 99  ASN   A CB   1 
ATOM   1490  C  CG   . ASN   A 1 100 ? 30.916  19.662  18.658  1.00 42.55 ? 99  ASN   A CG   1 
ATOM   1491  O  OD1  . ASN   A 1 100 ? 29.858  19.802  19.282  1.00 47.84 ? 99  ASN   A OD1  1 
ATOM   1492  N  ND2  . ASN   A 1 100 ? 32.068  20.121  19.103  1.00 40.48 ? 99  ASN   A ND2  1 
ATOM   1493  H  H    . ASN   A 1 100 ? 32.985  17.053  16.147  1.00 36.80 ? 99  ASN   A H    1 
ATOM   1494  H  HA   . ASN   A 1 100 ? 32.308  17.584  18.088  1.00 43.26 ? 99  ASN   A HA   1 
ATOM   1495  H  HB2  . ASN   A 1 100 ? 31.497  19.466  16.716  1.00 45.74 ? 99  ASN   A HB2  1 
ATOM   1496  H  HB3  . ASN   A 1 100 ? 30.057  18.854  16.997  1.00 45.74 ? 99  ASN   A HB3  1 
ATOM   1497  H  HD21 . ASN   A 1 100 ? 32.103  20.542  19.852  1.00 48.58 ? 99  ASN   A HD21 1 
ATOM   1498  H  HD22 . ASN   A 1 100 ? 32.785  20.000  18.644  1.00 48.58 ? 99  ASN   A HD22 1 
ATOM   1499  N  N    . GLY   A 1 101 ? 30.803  15.269  17.784  1.00 26.56 ? 100 GLY   A N    1 
ATOM   1500  C  CA   . GLY   A 1 101 ? 29.831  14.305  18.239  1.00 30.68 ? 100 GLY   A CA   1 
ATOM   1501  C  C    . GLY   A 1 101 ? 28.619  14.149  17.352  1.00 31.32 ? 100 GLY   A C    1 
ATOM   1502  O  O    . GLY   A 1 101 ? 27.661  13.469  17.760  1.00 28.00 ? 100 GLY   A O    1 
ATOM   1503  H  H    . GLY   A 1 101 ? 31.510  14.948  17.415  1.00 31.87 ? 100 GLY   A H    1 
ATOM   1504  H  HA2  . GLY   A 1 101 ? 30.262  13.439  18.305  1.00 36.82 ? 100 GLY   A HA2  1 
ATOM   1505  H  HA3  . GLY   A 1 101 ? 29.520  14.571  19.119  1.00 36.82 ? 100 GLY   A HA3  1 
ATOM   1506  N  N    . LEU   A 1 102 ? 28.635  14.726  16.140  1.00 20.98 ? 101 LEU   A N    1 
ATOM   1507  C  CA   . LEU   A 1 102 ? 27.584  14.501  15.163  1.00 20.13 ? 101 LEU   A CA   1 
ATOM   1508  C  C    . LEU   A 1 102 ? 28.194  13.612  14.086  1.00 18.44 ? 101 LEU   A C    1 
ATOM   1509  O  O    . LEU   A 1 102 ? 29.322  13.850  13.639  1.00 23.99 ? 101 LEU   A O    1 
ATOM   1510  C  CB   . LEU   A 1 102 ? 27.113  15.812  14.512  1.00 21.46 ? 101 LEU   A CB   1 
ATOM   1511  C  CG   . LEU   A 1 102 ? 26.325  16.795  15.367  1.00 23.96 ? 101 LEU   A CG   1 
ATOM   1512  C  CD1  . LEU   A 1 102 ? 26.188  18.161  14.705  1.00 25.25 ? 101 LEU   A CD1  1 
ATOM   1513  C  CD2  . LEU   A 1 102 ? 24.950  16.216  15.667  1.00 27.03 ? 101 LEU   A CD2  1 
ATOM   1514  H  H    . LEU   A 1 102 ? 29.256  15.255  15.868  1.00 25.17 ? 101 LEU   A H    1 
ATOM   1515  H  HA   . LEU   A 1 102 ? 26.809  14.092  15.577  1.00 24.16 ? 101 LEU   A HA   1 
ATOM   1516  H  HB2  . LEU   A 1 102 ? 27.901  16.284  14.199  1.00 25.75 ? 101 LEU   A HB2  1 
ATOM   1517  H  HB3  . LEU   A 1 102 ? 26.546  15.579  13.761  1.00 25.75 ? 101 LEU   A HB3  1 
ATOM   1518  H  HG   . LEU   A 1 102 ? 26.809  16.936  16.196  1.00 28.76 ? 101 LEU   A HG   1 
ATOM   1519  H  HD11 . LEU   A 1 102 ? 25.705  18.754  15.300  1.00 30.30 ? 101 LEU   A HD11 1 
ATOM   1520  H  HD12 . LEU   A 1 102 ? 27.073  18.517  14.530  1.00 30.30 ? 101 LEU   A HD12 1 
ATOM   1521  H  HD13 . LEU   A 1 102 ? 25.702  18.061  13.871  1.00 30.30 ? 101 LEU   A HD13 1 
ATOM   1522  H  HD21 . LEU   A 1 102 ? 24.284  16.913  15.561  1.00 32.43 ? 101 LEU   A HD21 1 
ATOM   1523  H  HD22 . LEU   A 1 102 ? 24.771  15.491  15.048  1.00 32.43 ? 101 LEU   A HD22 1 
ATOM   1524  H  HD23 . LEU   A 1 102 ? 24.939  15.883  16.578  1.00 32.43 ? 101 LEU   A HD23 1 
ATOM   1525  N  N    . THR   A 1 103 ? 27.467  12.602  13.671  1.00 17.42 ? 102 THR   A N    1 
ATOM   1526  C  CA   . THR   A 1 103 ? 27.929  11.762  12.564  1.00 16.86 ? 102 THR   A CA   1 
ATOM   1527  C  C    . THR   A 1 103 ? 27.633  12.449  11.240  1.00 17.60 ? 102 THR   A C    1 
ATOM   1528  O  O    . THR   A 1 103 ? 26.475  12.739  10.929  1.00 16.85 ? 102 THR   A O    1 
ATOM   1529  C  CB   . THR   A 1 103 ? 27.265  10.400  12.629  1.00 22.05 ? 102 THR   A CB   1 
ATOM   1530  O  OG1  . THR   A 1 103 ? 27.424  9.878   13.960  1.00 23.03 ? 102 THR   A OG1  1 
ATOM   1531  C  CG2  . THR   A 1 103 ? 27.859  9.456   11.574  1.00 20.04 ? 102 THR   A CG2  1 
ATOM   1532  H  H    . THR   A 1 103 ? 26.707  12.375  14.004  1.00 20.91 ? 102 THR   A H    1 
ATOM   1533  H  HA   . THR   A 1 103 ? 28.888  11.637  12.630  1.00 20.23 ? 102 THR   A HA   1 
ATOM   1534  H  HB   . THR   A 1 103 ? 26.317  10.466  12.432  1.00 26.46 ? 102 THR   A HB   1 
ATOM   1535  H  HG1  . THR   A 1 103 ? 26.944  9.197   14.061  1.00 27.64 ? 102 THR   A HG1  1 
ATOM   1536  H  HG21 . THR   A 1 103 ? 27.676  8.534   11.814  1.00 24.05 ? 102 THR   A HG21 1 
ATOM   1537  H  HG22 . THR   A 1 103 ? 27.466  9.640   10.707  1.00 24.05 ? 102 THR   A HG22 1 
ATOM   1538  H  HG23 . THR   A 1 103 ? 28.819  9.583   11.519  1.00 24.05 ? 102 THR   A HG23 1 
ATOM   1539  N  N    . SER   A 1 104 ? 28.666  12.652  10.442  1.00 17.31 ? 103 SER   A N    1 
ATOM   1540  C  CA   . SER   A 1 104 ? 28.507  13.178  9.089   1.00 18.22 ? 103 SER   A CA   1 
ATOM   1541  C  C    . SER   A 1 104 ? 28.821  12.066  8.085   1.00 16.53 ? 103 SER   A C    1 
ATOM   1542  O  O    . SER   A 1 104 ? 28.937  10.890  8.438   1.00 17.16 ? 103 SER   A O    1 
ATOM   1543  C  CB   . SER   A 1 104 ? 29.398  14.403  8.898   1.00 18.52 ? 103 SER   A CB   1 
ATOM   1544  O  OG   . SER   A 1 104 ? 29.066  15.149  7.711   1.00 18.31 ? 103 SER   A OG   1 
ATOM   1545  H  H    . SER   A 1 104 ? 29.483  12.492  10.661  1.00 20.77 ? 103 SER   A H    1 
ATOM   1546  H  HA   . SER   A 1 104 ? 27.588  13.460  8.956   1.00 21.86 ? 103 SER   A HA   1 
ATOM   1547  H  HB2  . SER   A 1 104 ? 29.293  14.985  9.667   1.00 22.22 ? 103 SER   A HB2  1 
ATOM   1548  H  HB3  . SER   A 1 104 ? 30.319  14.108  8.829   1.00 22.22 ? 103 SER   A HB3  1 
ATOM   1549  H  HG   . SER   A 1 104 ? 28.232  15.180  7.615   1.00 21.97 ? 103 SER   A HG   1 
ATOM   1550  N  N    . ILE   A 1 105 ? 28.950  12.434  6.809   1.00 16.77 ? 104 ILE   A N    1 
ATOM   1551  C  CA   . ILE   A 1 105 ? 29.343  11.498  5.769   1.00 19.22 ? 104 ILE   A CA   1 
ATOM   1552  C  C    . ILE   A 1 105 ? 30.358  12.181  4.858   1.00 18.08 ? 104 ILE   A C    1 
ATOM   1553  O  O    . ILE   A 1 105 ? 30.113  13.288  4.366   1.00 16.22 ? 104 ILE   A O    1 
ATOM   1554  C  CB   . ILE   A 1 105 ? 28.168  11.005  4.895   1.00 17.73 ? 104 ILE   A CB   1 
ATOM   1555  C  CG1  . ILE   A 1 105 ? 26.884  10.809  5.679   1.00 16.84 ? 104 ILE   A CG1  1 
ATOM   1556  C  CG2  . ILE   A 1 105 ? 28.603  9.733   4.140   1.00 20.60 ? 104 ILE   A CG2  1 
ATOM   1557  C  CD1  . ILE   A 1 105 ? 25.708  10.501  4.774   1.00 21.07 ? 104 ILE   A CD1  1 
ATOM   1558  H  H    . ILE   A 1 105 ? 28.812  13.233  6.523   1.00 20.12 ? 104 ILE   A H    1 
ATOM   1559  H  HA   . ILE   A 1 105 ? 29.742  10.733  6.211   1.00 23.06 ? 104 ILE   A HA   1 
ATOM   1560  H  HB   . ILE   A 1 105 ? 27.954  11.699  4.252   1.00 21.27 ? 104 ILE   A HB   1 
ATOM   1561  H  HG12 . ILE   A 1 105 ? 26.996  10.068  6.295   1.00 20.20 ? 104 ILE   A HG12 1 
ATOM   1562  H  HG13 . ILE   A 1 105 ? 26.684  11.621  6.171   1.00 20.20 ? 104 ILE   A HG13 1 
ATOM   1563  H  HG21 . ILE   A 1 105 ? 27.923  9.504   3.488   1.00 24.72 ? 104 ILE   A HG21 1 
ATOM   1564  H  HG22 . ILE   A 1 105 ? 29.447  9.905   3.692   1.00 24.72 ? 104 ILE   A HG22 1 
ATOM   1565  H  HG23 . ILE   A 1 105 ? 28.708  9.008   4.776   1.00 24.72 ? 104 ILE   A HG23 1 
ATOM   1566  H  HD11 . ILE   A 1 105 ? 24.884  10.649  5.264   1.00 25.28 ? 104 ILE   A HD11 1 
ATOM   1567  H  HD12 . ILE   A 1 105 ? 25.742  11.087  4.001   1.00 25.28 ? 104 ILE   A HD12 1 
ATOM   1568  H  HD13 . ILE   A 1 105 ? 25.762  9.575   4.490   1.00 25.28 ? 104 ILE   A HD13 1 
ATOM   1569  N  N    . LYS   A 1 106 ? 31.501  11.545  4.646   1.00 19.10 ? 105 LYS   A N    1 
ATOM   1570  C  CA   . LYS   A 1 106 ? 32.434  12.050  3.632   1.00 17.41 ? 105 LYS   A CA   1 
ATOM   1571  C  C    . LYS   A 1 106 ? 31.806  11.992  2.243   1.00 17.90 ? 105 LYS   A C    1 
ATOM   1572  O  O    . LYS   A 1 106 ? 31.053  11.072  1.928   1.00 18.42 ? 105 LYS   A O    1 
ATOM   1573  C  CB   . LYS   A 1 106 ? 33.724  11.243  3.673   1.00 23.17 ? 105 LYS   A CB   1 
ATOM   1574  C  CG   . LYS   A 1 106 ? 34.791  11.728  2.700   1.00 21.95 ? 105 LYS   A CG   1 
ATOM   1575  C  CD   . LYS   A 1 106 ? 35.836  10.638  2.510   1.00 25.00 ? 105 LYS   A CD   1 
ATOM   1576  C  CE   . LYS   A 1 106 ? 36.998  11.101  1.639   1.00 31.41 ? 105 LYS   A CE   1 
ATOM   1577  N  NZ   . LYS   A 1 106 ? 38.163  10.246  1.954   1.00 38.56 ? 105 LYS   A NZ   1 
ATOM   1578  H  H    . LYS   A 1 106 ? 31.760  10.838  5.061   1.00 22.92 ? 105 LYS   A H    1 
ATOM   1579  H  HA   . LYS   A 1 106 ? 32.650  12.977  3.818   1.00 20.89 ? 105 LYS   A HA   1 
ATOM   1580  H  HB2  . LYS   A 1 106 ? 34.094  11.295  4.568   1.00 27.80 ? 105 LYS   A HB2  1 
ATOM   1581  H  HB3  . LYS   A 1 106 ? 33.520  10.320  3.452   1.00 27.80 ? 105 LYS   A HB3  1 
ATOM   1582  H  HG2  . LYS   A 1 106 ? 34.387  11.928  1.841   1.00 26.34 ? 105 LYS   A HG2  1 
ATOM   1583  H  HG3  . LYS   A 1 106 ? 35.225  12.520  3.055   1.00 26.34 ? 105 LYS   A HG3  1 
ATOM   1584  H  HD2  . LYS   A 1 106 ? 36.190  10.382  3.376   1.00 30.00 ? 105 LYS   A HD2  1 
ATOM   1585  H  HD3  . LYS   A 1 106 ? 35.423  9.872   2.081   1.00 30.00 ? 105 LYS   A HD3  1 
ATOM   1586  H  HE2  . LYS   A 1 106 ? 36.773  11.005  0.700   1.00 37.70 ? 105 LYS   A HE2  1 
ATOM   1587  H  HE3  . LYS   A 1 106 ? 37.216  12.026  1.835   1.00 37.70 ? 105 LYS   A HE3  1 
ATOM   1588  H  HZ1  . LYS   A 1 106 ? 38.815  10.391  1.365   1.00 46.27 ? 105 LYS   A HZ1  1 
ATOM   1589  H  HZ2  . LYS   A 1 106 ? 38.464  10.431  2.770   1.00 46.27 ? 105 LYS   A HZ2  1 
ATOM   1590  H  HZ3  . LYS   A 1 106 ? 37.928  9.388   1.919   1.00 46.27 ? 105 LYS   A HZ3  1 
ATOM   1591  N  N    . TRP   A 1 107 ? 32.085  13.028  1.437   1.00 18.34 ? 106 TRP   A N    1 
ATOM   1592  C  CA   . TRP   A 1 107 ? 31.414  13.182  0.153   1.00 16.84 ? 106 TRP   A CA   1 
ATOM   1593  C  C    . TRP   A 1 107 ? 31.691  11.980  -0.740  1.00 16.84 ? 106 TRP   A C    1 
ATOM   1594  O  O    . TRP   A 1 107 ? 32.842  11.533  -0.886  1.00 17.87 ? 106 TRP   A O    1 
ATOM   1595  C  CB   . TRP   A 1 107 ? 31.809  14.488  -0.553  1.00 17.83 ? 106 TRP   A CB   1 
ATOM   1596  C  CG   . TRP   A 1 107 ? 30.878  14.702  -1.729  1.00 17.24 ? 106 TRP   A CG   1 
ATOM   1597  C  CD1  . TRP   A 1 107 ? 29.708  15.403  -1.744  1.00 19.46 ? 106 TRP   A CD1  1 
ATOM   1598  C  CD2  . TRP   A 1 107 ? 31.035  14.165  -3.069  1.00 17.56 ? 106 TRP   A CD2  1 
ATOM   1599  N  NE1  . TRP   A 1 107 ? 29.109  15.314  -2.981  1.00 22.55 ? 106 TRP   A NE1  1 
ATOM   1600  C  CE2  . TRP   A 1 107 ? 29.897  14.560  -3.809  1.00 16.93 ? 106 TRP   A CE2  1 
ATOM   1601  C  CE3  . TRP   A 1 107 ? 32.005  13.374  -3.688  1.00 18.24 ? 106 TRP   A CE3  1 
ATOM   1602  C  CZ2  . TRP   A 1 107 ? 29.727  14.225  -5.168  1.00 20.05 ? 106 TRP   A CZ2  1 
ATOM   1603  C  CZ3  . TRP   A 1 107 ? 31.815  13.015  -5.056  1.00 18.00 ? 106 TRP   A CZ3  1 
ATOM   1604  C  CH2  . TRP   A 1 107 ? 30.695  13.434  -5.752  1.00 22.71 ? 106 TRP   A CH2  1 
ATOM   1605  H  H    . TRP   A 1 107 ? 32.656  13.646  1.615   1.00 22.00 ? 106 TRP   A H    1 
ATOM   1606  H  HA   . TRP   A 1 107 ? 30.459  13.235  0.317   1.00 20.21 ? 106 TRP   A HA   1 
ATOM   1607  H  HB2  . TRP   A 1 107 ? 31.723  15.235  0.060   1.00 21.40 ? 106 TRP   A HB2  1 
ATOM   1608  H  HB3  . TRP   A 1 107 ? 32.721  14.427  -0.877  1.00 21.40 ? 106 TRP   A HB3  1 
ATOM   1609  H  HD1  . TRP   A 1 107 ? 29.363  15.875  -1.020  1.00 23.35 ? 106 TRP   A HD1  1 
ATOM   1610  H  HE1  . TRP   A 1 107 ? 28.360  15.676  -3.200  1.00 27.06 ? 106 TRP   A HE1  1 
ATOM   1611  H  HE3  . TRP   A 1 107 ? 32.756  13.088  -3.220  1.00 21.89 ? 106 TRP   A HE3  1 
ATOM   1612  H  HZ2  . TRP   A 1 107 ? 28.992  14.526  -5.652  1.00 24.06 ? 106 TRP   A HZ2  1 
ATOM   1613  H  HZ3  . TRP   A 1 107 ? 32.453  12.492  -5.486  1.00 21.59 ? 106 TRP   A HZ3  1 
ATOM   1614  H  HH2  . TRP   A 1 107 ? 30.591  13.174  -6.639  1.00 27.26 ? 106 TRP   A HH2  1 
ATOM   1615  N  N    . ALA   A 1 108 ? 30.616  11.432  -1.290  1.00 17.00 ? 107 ALA   A N    1 
ATOM   1616  C  CA   . ALA   A 1 108 ? 30.694  10.385  -2.305  1.00 19.78 ? 107 ALA   A CA   1 
ATOM   1617  C  C    . ALA   A 1 108 ? 29.338  10.308  -2.992  1.00 18.80 ? 107 ALA   A C    1 
ATOM   1618  O  O    . ALA   A 1 108 ? 28.310  10.514  -2.358  1.00 18.17 ? 107 ALA   A O    1 
ATOM   1619  C  CB   . ALA   A 1 108 ? 31.059  9.022   -1.686  1.00 19.08 ? 107 ALA   A CB   1 
ATOM   1620  H  H    . ALA   A 1 108 ? 29.810  11.653  -1.090  1.00 20.40 ? 107 ALA   A H    1 
ATOM   1621  H  HA   . ALA   A 1 108 ? 31.373  10.604  -2.962  1.00 23.74 ? 107 ALA   A HA   1 
ATOM   1622  H  HB1  . ALA   A 1 108 ? 30.601  8.321   -2.176  1.00 22.90 ? 107 ALA   A HB1  1 
ATOM   1623  H  HB2  . ALA   A 1 108 ? 32.018  8.895   -1.745  1.00 22.90 ? 107 ALA   A HB2  1 
ATOM   1624  H  HB3  . ALA   A 1 108 ? 30.780  9.013   -0.757  1.00 22.90 ? 107 ALA   A HB3  1 
ATOM   1625  N  N    . ASP   A 1 109 ? 29.325  10.008  -4.296  1.00 17.92 ? 108 ASP   A N    1 
ATOM   1626  C  CA   . ASP   A 1 109 ? 28.066  9.591   -4.924  1.00 17.71 ? 108 ASP   A CA   1 
ATOM   1627  C  C    . ASP   A 1 109 ? 26.930  10.617  -4.741  1.00 17.57 ? 108 ASP   A C    1 
ATOM   1628  O  O    . ASP   A 1 109 ? 25.763  10.249  -4.553  1.00 18.69 ? 108 ASP   A O    1 
ATOM   1629  C  CB   . ASP   A 1 109 ? 27.628  8.222   -4.380  1.00 20.21 ? 108 ASP   A CB   1 
ATOM   1630  C  CG   . ASP   A 1 109 ? 28.660  7.116   -4.598  1.00 26.69 ? 108 ASP   A CG   1 
ATOM   1631  O  OD1  . ASP   A 1 109 ? 29.169  6.992   -5.728  1.00 23.01 ? 108 ASP   A OD1  1 
ATOM   1632  O  OD2  . ASP   A 1 109 ? 28.923  6.325   -3.662  1.00 22.63 ? 108 ASP   A OD2  1 
ATOM   1633  H  H    . ASP   A 1 109 ? 30.008  10.037  -4.819  1.00 21.50 ? 108 ASP   A H    1 
ATOM   1634  H  HA   . ASP   A 1 109 ? 28.227  9.529   -5.879  1.00 21.25 ? 108 ASP   A HA   1 
ATOM   1635  H  HB2  . ASP   A 1 109 ? 27.475  8.299   -3.426  1.00 24.25 ? 108 ASP   A HB2  1 
ATOM   1636  H  HB3  . ASP   A 1 109 ? 26.810  7.955   -4.827  1.00 24.25 ? 108 ASP   A HB3  1 
ATOM   1637  N  N    . ASN   A 1 110 ? 27.258  11.912  -4.844  1.00 18.68 ? 109 ASN   A N    1 
ATOM   1638  C  CA   . ASN   A 1 110 ? 26.301  13.021  -4.687  1.00 18.18 ? 109 ASN   A CA   1 
ATOM   1639  C  C    . ASN   A 1 110 ? 25.478  12.904  -3.395  1.00 19.29 ? 109 ASN   A C    1 
ATOM   1640  O  O    . ASN   A 1 110 ? 24.264  13.175  -3.353  1.00 19.09 ? 109 ASN   A O    1 
ATOM   1641  C  CB   . ASN   A 1 110 ? 25.354  13.173  -5.870  1.00 23.45 ? 109 ASN   A CB   1 
ATOM   1642  C  CG   . ASN   A 1 110 ? 26.099  13.518  -7.152  1.00 29.82 ? 109 ASN   A CG   1 
ATOM   1643  O  OD1  . ASN   A 1 110 ? 26.897  14.445  -7.167  1.00 28.22 ? 109 ASN   A OD1  1 
ATOM   1644  N  ND2  . ASN   A 1 110 ? 25.712  12.890  -8.254  1.00 35.73 ? 109 ASN   A ND2  1 
ATOM   1645  H  H    . ASN   A 1 110 ? 28.057  12.185  -5.009  1.00 22.42 ? 109 ASN   A H    1 
ATOM   1646  H  HA   . ASN   A 1 110 ? 26.848  13.820  -4.638  1.00 21.82 ? 109 ASN   A HA   1 
ATOM   1647  H  HB2  . ASN   A 1 110 ? 24.880  12.337  -6.009  1.00 28.14 ? 109 ASN   A HB2  1 
ATOM   1648  H  HB3  . ASN   A 1 110 ? 24.722  13.885  -5.684  1.00 28.14 ? 109 ASN   A HB3  1 
ATOM   1649  H  HD21 . ASN   A 1 110 ? 25.069  12.319  -8.221  1.00 42.87 ? 109 ASN   A HD21 1 
ATOM   1650  H  HD22 . ASN   A 1 110 ? 26.103  13.053  -9.002  1.00 42.87 ? 109 ASN   A HD22 1 
ATOM   1651  N  N    . ASN   A 1 111 ? 26.138  12.524  -2.328  1.00 17.53 ? 110 ASN   A N    1 
ATOM   1652  C  CA   . ASN   A 1 111 ? 25.450  12.259  -1.072  1.00 15.01 ? 110 ASN   A CA   1 
ATOM   1653  C  C    . ASN   A 1 111 ? 25.398  13.463  -0.129  1.00 15.74 ? 110 ASN   A C    1 
ATOM   1654  O  O    . ASN   A 1 111 ? 25.079  13.287  1.056   1.00 15.54 ? 110 ASN   A O    1 
ATOM   1655  C  CB   . ASN   A 1 111 ? 26.092  11.038  -0.399  1.00 13.87 ? 110 ASN   A CB   1 
ATOM   1656  C  CG   . ASN   A 1 111 ? 27.460  11.342  0.206   1.00 15.86 ? 110 ASN   A CG   1 
ATOM   1657  O  OD1  . ASN   A 1 111 ? 27.985  12.447  0.109   1.00 15.86 ? 110 ASN   A OD1  1 
ATOM   1658  N  ND2  . ASN   A 1 111 ? 28.053  10.331  0.799   1.00 17.41 ? 110 ASN   A ND2  1 
ATOM   1659  H  H    . ASN   A 1 111 ? 26.990  12.409  -2.298  1.00 21.03 ? 110 ASN   A H    1 
ATOM   1660  H  HA   . ASN   A 1 111 ? 24.524  12.044  -1.263  1.00 18.01 ? 110 ASN   A HA   1 
ATOM   1661  H  HB2  . ASN   A 1 111 ? 25.511  10.729  0.314   1.00 16.65 ? 110 ASN   A HB2  1 
ATOM   1662  H  HB3  . ASN   A 1 111 ? 26.206  10.337  -1.060  1.00 16.65 ? 110 ASN   A HB3  1 
ATOM   1663  H  HD21 . ASN   A 1 111 ? 28.826  10.437  1.160   1.00 20.89 ? 110 ASN   A HD21 1 
ATOM   1664  H  HD22 . ASN   A 1 111 ? 27.667  9.562   0.826   1.00 20.89 ? 110 ASN   A HD22 1 
ATOM   1665  N  N    . SER   A 1 112 ? 25.624  14.677  -0.621  1.00 17.79 ? 111 SER   A N    1 
ATOM   1666  C  CA   . SER   A 1 112 ? 25.597  15.832  0.275   1.00 15.91 ? 111 SER   A CA   1 
ATOM   1667  C  C    . SER   A 1 112 ? 24.227  15.991  0.923   1.00 17.66 ? 111 SER   A C    1 
ATOM   1668  O  O    . SER   A 1 112 ? 24.148  16.405  2.080   1.00 17.26 ? 111 SER   A O    1 
ATOM   1669  C  CB   . SER   A 1 112 ? 25.943  17.143  -0.439  1.00 20.71 ? 111 SER   A CB   1 
ATOM   1670  O  OG   . SER   A 1 112 ? 24.996  17.481  -1.440  1.00 17.97 ? 111 SER   A OG   1 
ATOM   1671  H  H    . SER   A 1 112 ? 25.791  14.856  -1.446  1.00 21.35 ? 111 SER   A H    1 
ATOM   1672  H  HA   . SER   A 1 112 ? 26.279  15.678  0.947   1.00 19.09 ? 111 SER   A HA   1 
ATOM   1673  H  HB2  . SER   A 1 112 ? 25.966  17.857  0.218   1.00 24.85 ? 111 SER   A HB2  1 
ATOM   1674  H  HB3  . SER   A 1 112 ? 26.813  17.048  -0.856  1.00 24.85 ? 111 SER   A HB3  1 
ATOM   1675  H  HG   . SER   A 1 112 ? 25.348  17.992  -2.007  1.00 21.57 ? 111 SER   A HG   1 
ATOM   1676  N  N    . TYR   A 1 113 ? 23.140  15.653  0.204   1.00 14.59 ? 112 TYR   A N    1 
ATOM   1677  C  CA   . TYR   A 1 113 ? 21.801  15.798  0.760   1.00 15.64 ? 112 TYR   A CA   1 
ATOM   1678  C  C    . TYR   A 1 113 ? 21.604  14.856  1.934   1.00 17.93 ? 112 TYR   A C    1 
ATOM   1679  O  O    . TYR   A 1 113 ? 20.923  15.198  2.901   1.00 17.27 ? 112 TYR   A O    1 
ATOM   1680  C  CB   . TYR   A 1 113 ? 20.717  15.565  -0.310  1.00 17.29 ? 112 TYR   A CB   1 
ATOM   1681  C  CG   . TYR   A 1 113 ? 20.444  14.135  -0.715  1.00 15.39 ? 112 TYR   A CG   1 
ATOM   1682  C  CD1  . TYR   A 1 113 ? 21.339  13.451  -1.521  1.00 15.62 ? 112 TYR   A CD1  1 
ATOM   1683  C  CD2  . TYR   A 1 113 ? 19.260  13.477  -0.316  1.00 17.45 ? 112 TYR   A CD2  1 
ATOM   1684  C  CE1  . TYR   A 1 113 ? 21.083  12.122  -1.917  1.00 17.50 ? 112 TYR   A CE1  1 
ATOM   1685  C  CE2  . TYR   A 1 113 ? 18.996  12.184  -0.698  1.00 16.89 ? 112 TYR   A CE2  1 
ATOM   1686  C  CZ   . TYR   A 1 113 ? 19.904  11.505  -1.528  1.00 17.40 ? 112 TYR   A CZ   1 
ATOM   1687  O  OH   . TYR   A 1 113 ? 19.656  10.205  -1.923  1.00 19.29 ? 112 TYR   A OH   1 
ATOM   1688  H  H    . TYR   A 1 113 ? 23.160  15.342  -0.598  1.00 17.50 ? 112 TYR   A H    1 
ATOM   1689  H  HA   . TYR   A 1 113 ? 21.699  16.712  1.069   1.00 18.77 ? 112 TYR   A HA   1 
ATOM   1690  H  HB2  . TYR   A 1 113 ? 19.882  15.927  0.027   1.00 20.75 ? 112 TYR   A HB2  1 
ATOM   1691  H  HB3  . TYR   A 1 113 ? 20.983  16.040  -1.113  1.00 20.75 ? 112 TYR   A HB3  1 
ATOM   1692  H  HD1  . TYR   A 1 113 ? 22.117  13.873  -1.804  1.00 18.74 ? 112 TYR   A HD1  1 
ATOM   1693  H  HD2  . TYR   A 1 113 ? 18.645  13.929  0.216   1.00 20.94 ? 112 TYR   A HD2  1 
ATOM   1694  H  HE1  . TYR   A 1 113 ? 21.702  11.662  -2.436  1.00 21.00 ? 112 TYR   A HE1  1 
ATOM   1695  H  HE2  . TYR   A 1 113 ? 18.221  11.761  -0.409  1.00 20.27 ? 112 TYR   A HE2  1 
ATOM   1696  H  HH   . TYR   A 1 113 ? 18.853  10.008  -1.773  1.00 23.15 ? 112 TYR   A HH   1 
ATOM   1697  N  N    . LEU   A 1 114 ? 22.201  13.670  1.856   1.00 16.76 ? 113 LEU   A N    1 
ATOM   1698  C  CA   . LEU   A 1 114 ? 22.076  12.678  2.913   1.00 19.94 ? 113 LEU   A CA   1 
ATOM   1699  C  C    . LEU   A 1 114 ? 22.888  13.057  4.134   1.00 19.21 ? 113 LEU   A C    1 
ATOM   1700  O  O    . LEU   A 1 114 ? 22.403  12.910  5.263   1.00 18.21 ? 113 LEU   A O    1 
ATOM   1701  C  CB   . LEU   A 1 114 ? 22.512  11.315  2.392   1.00 20.38 ? 113 LEU   A CB   1 
ATOM   1702  C  CG   . LEU   A 1 114 ? 21.482  10.652  1.493   1.00 23.61 ? 113 LEU   A CG   1 
ATOM   1703  C  CD1  . LEU   A 1 114 ? 22.115  9.399   0.850   1.00 26.48 ? 113 LEU   A CD1  1 
ATOM   1704  C  CD2  . LEU   A 1 114 ? 20.197  10.275  2.230   1.00 22.38 ? 113 LEU   A CD2  1 
ATOM   1705  H  H    . LEU   A 1 114 ? 22.687  13.413  1.195   1.00 20.11 ? 113 LEU   A H    1 
ATOM   1706  H  HA   . LEU   A 1 114 ? 21.145  12.624  3.181   1.00 23.93 ? 113 LEU   A HA   1 
ATOM   1707  H  HB2  . LEU   A 1 114 ? 23.329  11.423  1.880   1.00 24.46 ? 113 LEU   A HB2  1 
ATOM   1708  H  HB3  . LEU   A 1 114 ? 22.670  10.728  3.148   1.00 24.46 ? 113 LEU   A HB3  1 
ATOM   1709  H  HG   . LEU   A 1 114 ? 21.219  11.289  0.809   1.00 28.33 ? 113 LEU   A HG   1 
ATOM   1710  H  HD11 . LEU   A 1 114 ? 21.474  8.996   0.244   1.00 31.77 ? 113 LEU   A HD11 1 
ATOM   1711  H  HD12 . LEU   A 1 114 ? 22.911  9.662   0.362   1.00 31.77 ? 113 LEU   A HD12 1 
ATOM   1712  H  HD13 . LEU   A 1 114 ? 22.350  8.769   1.550   1.00 31.77 ? 113 LEU   A HD13 1 
ATOM   1713  H  HD21 . LEU   A 1 114 ? 19.780  9.526   1.776   1.00 26.85 ? 113 LEU   A HD21 1 
ATOM   1714  H  HD22 . LEU   A 1 114 ? 20.416  10.028  3.142   1.00 26.85 ? 113 LEU   A HD22 1 
ATOM   1715  H  HD23 . LEU   A 1 114 ? 19.597  11.037  2.229   1.00 26.85 ? 113 LEU   A HD23 1 
ATOM   1716  N  N    . ALA   A 1 115 ? 24.120  13.558  3.935   1.00 17.52 ? 114 ALA   A N    1 
ATOM   1717  C  CA   . ALA   A 1 115 ? 24.891  14.069  5.066   1.00 16.86 ? 114 ALA   A CA   1 
ATOM   1718  C  C    . ALA   A 1 115 ? 24.144  15.201  5.770   1.00 17.83 ? 114 ALA   A C    1 
ATOM   1719  O  O    . ALA   A 1 115 ? 24.026  15.217  7.002   1.00 15.67 ? 114 ALA   A O    1 
ATOM   1720  C  CB   . ALA   A 1 115 ? 26.277  14.523  4.616   1.00 17.82 ? 114 ALA   A CB   1 
ATOM   1721  H  H    . ALA   A 1 115 ? 24.516  13.610  3.173   1.00 21.02 ? 114 ALA   A H    1 
ATOM   1722  H  HA   . ALA   A 1 115 ? 25.017  13.348  5.702   1.00 20.23 ? 114 ALA   A HA   1 
ATOM   1723  H  HB1  . ALA   A 1 115 ? 26.751  14.892  5.378   1.00 21.39 ? 114 ALA   A HB1  1 
ATOM   1724  H  HB2  . ALA   A 1 115 ? 26.760  13.759  4.264   1.00 21.39 ? 114 ALA   A HB2  1 
ATOM   1725  H  HB3  . ALA   A 1 115 ? 26.180  15.199  3.927   1.00 21.39 ? 114 ALA   A HB3  1 
ATOM   1726  N  N    . THR   A 1 116 ? 23.597  16.146  5.003   1.00 18.14 ? 115 THR   A N    1 
ATOM   1727  C  CA   . THR   A 1 116 ? 22.842  17.245  5.600   1.00 17.52 ? 115 THR   A CA   1 
ATOM   1728  C  C    . THR   A 1 116 ? 21.588  16.742  6.325   1.00 15.06 ? 115 THR   A C    1 
ATOM   1729  O  O    . THR   A 1 116 ? 21.299  17.185  7.450   1.00 18.08 ? 115 THR   A O    1 
ATOM   1730  C  CB   . THR   A 1 116 ? 22.517  18.279  4.502   1.00 18.45 ? 115 THR   A CB   1 
ATOM   1731  O  OG1  . THR   A 1 116 ? 23.763  18.737  3.946   1.00 21.65 ? 115 THR   A OG1  1 
ATOM   1732  C  CG2  . THR   A 1 116 ? 21.781  19.433  5.093   1.00 22.38 ? 115 THR   A CG2  1 
ATOM   1733  H  H    . THR   A 1 116 ? 23.649  16.173  4.145   1.00 21.77 ? 115 THR   A H    1 
ATOM   1734  H  HA   . THR   A 1 116 ? 23.378  17.690  6.275   1.00 21.02 ? 115 THR   A HA   1 
ATOM   1735  H  HB   . THR   A 1 116 ? 21.961  17.889  3.810   1.00 22.14 ? 115 THR   A HB   1 
ATOM   1736  H  HG1  . THR   A 1 116 ? 23.728  19.564  3.807   1.00 25.98 ? 115 THR   A HG1  1 
ATOM   1737  H  HG21 . THR   A 1 116 ? 21.684  20.138  4.433   1.00 26.86 ? 115 THR   A HG21 1 
ATOM   1738  H  HG22 . THR   A 1 116 ? 20.900  19.151  5.384   1.00 26.86 ? 115 THR   A HG22 1 
ATOM   1739  H  HG23 . THR   A 1 116 ? 22.268  19.782  5.856   1.00 26.86 ? 115 THR   A HG23 1 
ATOM   1740  N  N    . ALA   A 1 117 ? 20.865  15.779  5.744   1.00 16.42 ? 116 ALA   A N    1 
ATOM   1741  C  CA   . ALA   A 1 117 ? 19.699  15.205  6.432   1.00 18.24 ? 116 ALA   A CA   1 
ATOM   1742  C  C    . ALA   A 1 117 ? 20.101  14.450  7.702   1.00 15.68 ? 116 ALA   A C    1 
ATOM   1743  O  O    . ALA   A 1 117 ? 19.456  14.589  8.763   1.00 18.14 ? 116 ALA   A O    1 
ATOM   1744  C  CB   . ALA   A 1 117 ? 18.962  14.253  5.495   1.00 17.01 ? 116 ALA   A CB   1 
ATOM   1745  H  H    . ALA   A 1 117 ? 21.023  15.444  4.968   1.00 19.71 ? 116 ALA   A H    1 
ATOM   1746  H  HA   . ALA   A 1 117 ? 19.108  15.933  6.681   1.00 21.89 ? 116 ALA   A HA   1 
ATOM   1747  H  HB1  . ALA   A 1 117 ? 18.288  13.772  6.000   1.00 20.42 ? 116 ALA   A HB1  1 
ATOM   1748  H  HB2  . ALA   A 1 117 ? 18.540  14.768  4.789   1.00 20.42 ? 116 ALA   A HB2  1 
ATOM   1749  H  HB3  . ALA   A 1 117 ? 19.599  13.629  5.114   1.00 20.42 ? 116 ALA   A HB3  1 
ATOM   1750  N  N    . LEU   A 1 118 ? 21.175  13.654  7.611   1.00 18.16 ? 117 LEU   A N    1 
ATOM   1751  C  CA   . LEU   A 1 118 ? 21.638  12.885  8.775   1.00 18.32 ? 117 LEU   A CA   1 
ATOM   1752  C  C    . LEU   A 1 118 ? 22.026  13.810  9.924   1.00 16.47 ? 117 LEU   A C    1 
ATOM   1753  O  O    . LEU   A 1 118 ? 21.679  13.558  11.079  1.00 17.89 ? 117 LEU   A O    1 
ATOM   1754  C  CB   . LEU   A 1 118 ? 22.835  12.031  8.378   1.00 18.78 ? 117 LEU   A CB   1 
ATOM   1755  C  CG   . LEU   A 1 118 ? 23.598  11.235  9.443   1.00 16.79 ? 117 LEU   A CG   1 
ATOM   1756  C  CD1  . LEU   A 1 118 ? 22.651  10.299  10.110  1.00 23.10 ? 117 LEU   A CD1  1 
ATOM   1757  C  CD2  . LEU   A 1 118 ? 24.763  10.475  8.772   1.00 19.25 ? 117 LEU   A CD2  1 
ATOM   1758  H  H    . LEU   A 1 118 ? 21.646  13.543  6.900   1.00 21.79 ? 117 LEU   A H    1 
ATOM   1759  H  HA   . LEU   A 1 118 ? 20.919  12.305  9.072   1.00 21.98 ? 117 LEU   A HA   1 
ATOM   1760  H  HB2  . LEU   A 1 118 ? 22.522  11.381  7.730   1.00 22.53 ? 117 LEU   A HB2  1 
ATOM   1761  H  HB3  . LEU   A 1 118 ? 23.485  12.622  7.967   1.00 22.53 ? 117 LEU   A HB3  1 
ATOM   1762  H  HG   . LEU   A 1 118 ? 23.975  11.820  10.118  1.00 20.15 ? 117 LEU   A HG   1 
ATOM   1763  H  HD11 . LEU   A 1 118 ? 23.119  9.478   10.328  1.00 27.72 ? 117 LEU   A HD11 1 
ATOM   1764  H  HD12 . LEU   A 1 118 ? 22.314  10.713  10.919  1.00 27.72 ? 117 LEU   A HD12 1 
ATOM   1765  H  HD13 . LEU   A 1 118 ? 21.916  10.109  9.505   1.00 27.72 ? 117 LEU   A HD13 1 
ATOM   1766  H  HD21 . LEU   A 1 118 ? 25.319  10.079  9.461   1.00 23.10 ? 117 LEU   A HD21 1 
ATOM   1767  H  HD22 . LEU   A 1 118 ? 24.400  9.782   8.200   1.00 23.10 ? 117 LEU   A HD22 1 
ATOM   1768  H  HD23 . LEU   A 1 118 ? 25.285  11.100  8.245   1.00 23.10 ? 117 LEU   A HD23 1 
ATOM   1769  N  N    . LEU   A 1 119 ? 22.806  14.869  9.622   1.00 17.27 ? 118 LEU   A N    1 
ATOM   1770  C  CA   . LEU   A 1 119 ? 23.171  15.852  10.646  1.00 18.73 ? 118 LEU   A CA   1 
ATOM   1771  C  C    . LEU   A 1 119 ? 21.933  16.498  11.280  1.00 18.60 ? 118 LEU   A C    1 
ATOM   1772  O  O    . LEU   A 1 119 ? 21.864  16.683  12.509  1.00 17.71 ? 118 LEU   A O    1 
ATOM   1773  C  CB   . LEU   A 1 119 ? 24.075  16.899  9.998   1.00 15.48 ? 118 LEU   A CB   1 
ATOM   1774  C  CG   . LEU   A 1 119 ? 25.469  16.350  9.641   1.00 17.89 ? 118 LEU   A CG   1 
ATOM   1775  C  CD1  . LEU   A 1 119 ? 26.092  17.243  8.614   1.00 17.35 ? 118 LEU   A CD1  1 
ATOM   1776  C  CD2  . LEU   A 1 119 ? 26.334  16.228  10.908  1.00 19.23 ? 118 LEU   A CD2  1 
ATOM   1777  H  H    . LEU   A 1 119 ? 23.129  15.033  8.842   1.00 20.72 ? 118 LEU   A H    1 
ATOM   1778  H  HA   . LEU   A 1 119 ? 23.654  15.419  11.367  1.00 22.48 ? 118 LEU   A HA   1 
ATOM   1779  H  HB2  . LEU   A 1 119 ? 23.657  17.212  9.181   1.00 18.57 ? 118 LEU   A HB2  1 
ATOM   1780  H  HB3  . LEU   A 1 119 ? 24.192  17.638  10.615  1.00 18.57 ? 118 LEU   A HB3  1 
ATOM   1781  H  HG   . LEU   A 1 119 ? 25.403  15.459  9.263   1.00 21.46 ? 118 LEU   A HG   1 
ATOM   1782  H  HD11 . LEU   A 1 119 ? 26.895  16.819  8.273   1.00 20.82 ? 118 LEU   A HD11 1 
ATOM   1783  H  HD12 . LEU   A 1 119 ? 25.459  17.384  7.893   1.00 20.82 ? 118 LEU   A HD12 1 
ATOM   1784  H  HD13 . LEU   A 1 119 ? 26.316  18.091  9.028   1.00 20.82 ? 118 LEU   A HD13 1 
ATOM   1785  H  HD21 . LEU   A 1 119 ? 27.230  15.957  10.653  1.00 23.08 ? 118 LEU   A HD21 1 
ATOM   1786  H  HD22 . LEU   A 1 119 ? 26.364  17.089  11.354  1.00 23.08 ? 118 LEU   A HD22 1 
ATOM   1787  H  HD23 . LEU   A 1 119 ? 25.942  15.564  11.495  1.00 23.08 ? 118 LEU   A HD23 1 
ATOM   1788  N  N    . THR   A 1 120 ? 20.938  16.840  10.455  1.00 14.96 ? 119 THR   A N    1 
ATOM   1789  C  CA   . THR   A 1 120 ? 19.717  17.437  10.954  1.00 15.13 ? 119 THR   A CA   1 
ATOM   1790  C  C    . THR   A 1 120 ? 18.968  16.473  11.858  1.00 14.95 ? 119 THR   A C    1 
ATOM   1791  O  O    . THR   A 1 120 ? 18.488  16.853  12.939  1.00 18.03 ? 119 THR   A O    1 
ATOM   1792  C  CB   . THR   A 1 120 ? 18.839  17.848  9.778   1.00 19.26 ? 119 THR   A CB   1 
ATOM   1793  O  OG1  . THR   A 1 120 ? 19.543  18.806  8.976   1.00 18.37 ? 119 THR   A OG1  1 
ATOM   1794  C  CG2  . THR   A 1 120 ? 17.508  18.439  10.301  1.00 17.16 ? 119 THR   A CG2  1 
ATOM   1795  H  H    . THR   A 1 120 ? 20.954  16.734  9.601   1.00 17.96 ? 119 THR   A H    1 
ATOM   1796  H  HA   . THR   A 1 120 ? 19.934  18.228  11.471  1.00 18.16 ? 119 THR   A HA   1 
ATOM   1797  H  HB   . THR   A 1 120 ? 18.625  17.082  9.224   1.00 23.11 ? 119 THR   A HB   1 
ATOM   1798  H  HG1  . THR   A 1 120 ? 19.850  18.435  8.288   1.00 22.04 ? 119 THR   A HG1  1 
ATOM   1799  H  HG21 . THR   A 1 120 ? 16.920  18.642  9.557   1.00 20.59 ? 119 THR   A HG21 1 
ATOM   1800  H  HG22 . THR   A 1 120 ? 17.069  17.801  10.885  1.00 20.59 ? 119 THR   A HG22 1 
ATOM   1801  H  HG23 . THR   A 1 120 ? 17.680  19.254  10.798  1.00 20.59 ? 119 THR   A HG23 1 
ATOM   1802  N  N    . LEU   A 1 121 ? 18.878  15.215  11.441  1.00 18.27 ? 120 LEU   A N    1 
ATOM   1803  C  CA   . LEU   A 1 121 ? 18.152  14.241  12.241  1.00 20.64 ? 120 LEU   A CA   1 
ATOM   1804  C  C    . LEU   A 1 121 ? 18.775  14.048  13.616  1.00 24.40 ? 120 LEU   A C    1 
ATOM   1805  O  O    . LEU   A 1 121 ? 18.087  13.603  14.533  1.00 24.70 ? 120 LEU   A O    1 
ATOM   1806  C  CB   . LEU   A 1 121 ? 18.088  12.909  11.522  1.00 20.95 ? 120 LEU   A CB   1 
ATOM   1807  C  CG   . LEU   A 1 121 ? 17.152  12.868  10.328  1.00 18.05 ? 120 LEU   A CG   1 
ATOM   1808  C  CD1  . LEU   A 1 121 ? 17.508  11.752  9.330   1.00 25.99 ? 120 LEU   A CD1  1 
ATOM   1809  C  CD2  . LEU   A 1 121 ? 15.709  12.815  10.722  1.00 23.39 ? 120 LEU   A CD2  1 
ATOM   1810  H  H    . LEU   A 1 121 ? 19.220  14.908  10.715  1.00 21.92 ? 120 LEU   A H    1 
ATOM   1811  H  HA   . LEU   A 1 121 ? 17.248  14.571  12.361  1.00 24.76 ? 120 LEU   A HA   1 
ATOM   1812  H  HB2  . LEU   A 1 121 ? 18.977  12.691  11.203  1.00 25.14 ? 120 LEU   A HB2  1 
ATOM   1813  H  HB3  . LEU   A 1 121 ? 17.787  12.235  12.152  1.00 25.14 ? 120 LEU   A HB3  1 
ATOM   1814  H  HG   . LEU   A 1 121 ? 17.277  13.708  9.860   1.00 21.66 ? 120 LEU   A HG   1 
ATOM   1815  H  HD11 . LEU   A 1 121 ? 16.952  11.846  8.540   1.00 31.18 ? 120 LEU   A HD11 1 
ATOM   1816  H  HD12 . LEU   A 1 121 ? 18.444  11.832  9.087   1.00 31.18 ? 120 LEU   A HD12 1 
ATOM   1817  H  HD13 . LEU   A 1 121 ? 17.347  10.891  9.747   1.00 31.18 ? 120 LEU   A HD13 1 
ATOM   1818  H  HD21 . LEU   A 1 121 ? 15.190  12.478  9.975   1.00 28.07 ? 120 LEU   A HD21 1 
ATOM   1819  H  HD22 . LEU   A 1 121 ? 15.612  12.223  11.485  1.00 28.07 ? 120 LEU   A HD22 1 
ATOM   1820  H  HD23 . LEU   A 1 121 ? 15.412  13.708  10.956  1.00 28.07 ? 120 LEU   A HD23 1 
ATOM   1821  N  N    . GLN   A 1 122 ? 20.068  14.319  13.774  1.00 17.10 ? 121 GLN   A N    1 
ATOM   1822  C  CA   . GLN   A 1 122 ? 20.702  14.185  15.090  1.00 17.71 ? 121 GLN   A CA   1 
ATOM   1823  C  C    . GLN   A 1 122 ? 20.463  15.396  15.975  1.00 17.75 ? 121 GLN   A C    1 
ATOM   1824  O  O    . GLN   A 1 122 ? 20.859  15.388  17.149  1.00 19.94 ? 121 GLN   A O    1 
ATOM   1825  C  CB   . GLN   A 1 122 ? 22.204  13.954  14.912  1.00 14.26 ? 121 GLN   A CB   1 
ATOM   1826  C  CG   . GLN   A 1 122 ? 22.507  12.589  14.404  1.00 18.12 ? 121 GLN   A CG   1 
ATOM   1827  C  CD   . GLN   A 1 122 ? 23.901  12.468  13.892  1.00 18.70 ? 121 GLN   A CD   1 
ATOM   1828  O  OE1  . GLN   A 1 122 ? 24.806  12.001  14.596  1.00 18.54 ? 121 GLN   A OE1  1 
ATOM   1829  N  NE2  . GLN   A 1 122 ? 24.096  12.852  12.621  1.00 16.64 ? 121 GLN   A NE2  1 
ATOM   1830  H  H    . GLN   A 1 122 ? 20.594  14.579  13.146  1.00 20.53 ? 121 GLN   A H    1 
ATOM   1831  H  HA   . GLN   A 1 122 ? 20.334  13.412  15.547  1.00 21.25 ? 121 GLN   A HA   1 
ATOM   1832  H  HB2  . GLN   A 1 122 ? 22.551  14.598  14.275  1.00 17.11 ? 121 GLN   A HB2  1 
ATOM   1833  H  HB3  . GLN   A 1 122 ? 22.646  14.062  15.769  1.00 17.11 ? 121 GLN   A HB3  1 
ATOM   1834  H  HG2  . GLN   A 1 122 ? 22.394  11.950  15.124  1.00 21.74 ? 121 GLN   A HG2  1 
ATOM   1835  H  HG3  . GLN   A 1 122 ? 21.900  12.380  13.676  1.00 21.74 ? 121 GLN   A HG3  1 
ATOM   1836  H  HE21 . GLN   A 1 122 ? 23.436  13.146  12.155  1.00 19.96 ? 121 GLN   A HE21 1 
ATOM   1837  H  HE22 . GLN   A 1 122 ? 24.881  12.804  12.273  1.00 19.96 ? 121 GLN   A HE22 1 
ATOM   1838  N  N    . GLN   A 1 123 ? 19.808  16.427  15.460  1.00 16.92 ? 122 GLN   A N    1 
ATOM   1839  C  CA   . GLN   A 1 123 ? 19.573  17.668  16.186  1.00 18.23 ? 122 GLN   A CA   1 
ATOM   1840  C  C    . GLN   A 1 123 ? 18.105  17.949  16.478  1.00 23.73 ? 122 GLN   A C    1 
ATOM   1841  O  O    . GLN   A 1 123 ? 17.797  18.938  17.153  1.00 23.58 ? 122 GLN   A O    1 
ATOM   1842  C  CB   . GLN   A 1 123 ? 20.151  18.840  15.381  1.00 17.67 ? 122 GLN   A CB   1 
ATOM   1843  C  CG   . GLN   A 1 123 ? 21.673  18.778  15.292  1.00 19.36 ? 122 GLN   A CG   1 
ATOM   1844  C  CD   . GLN   A 1 123 ? 22.258  19.851  14.437  1.00 20.10 ? 122 GLN   A CD   1 
ATOM   1845  O  OE1  . GLN   A 1 123 ? 22.286  21.026  14.806  1.00 21.27 ? 122 GLN   A OE1  1 
ATOM   1846  N  NE2  . GLN   A 1 123 ? 22.709  19.457  13.260  1.00 18.61 ? 122 GLN   A NE2  1 
ATOM   1847  H  H    . GLN   A 1 123 ? 19.478  16.433  14.665  1.00 20.31 ? 122 GLN   A H    1 
ATOM   1848  H  HA   . GLN   A 1 123 ? 20.028  17.619  17.041  1.00 21.88 ? 122 GLN   A HA   1 
ATOM   1849  H  HB2  . GLN   A 1 123 ? 19.794  18.815  14.480  1.00 21.21 ? 122 GLN   A HB2  1 
ATOM   1850  H  HB3  . GLN   A 1 123 ? 19.907  19.674  15.812  1.00 21.21 ? 122 GLN   A HB3  1 
ATOM   1851  H  HG2  . GLN   A 1 123 ? 22.044  18.872  16.183  1.00 23.23 ? 122 GLN   A HG2  1 
ATOM   1852  H  HG3  . GLN   A 1 123 ? 21.931  17.922  14.914  1.00 23.23 ? 122 GLN   A HG3  1 
ATOM   1853  H  HE21 . GLN   A 1 123 ? 22.653  18.629  13.033  1.00 22.33 ? 122 GLN   A HE21 1 
ATOM   1854  H  HE22 . GLN   A 1 123 ? 23.058  20.028  12.720  1.00 22.33 ? 122 GLN   A HE22 1 
ATOM   1855  N  N    . ILE   A 1 124 ? 17.197  17.169  15.942  1.00 17.04 ? 123 ILE   A N    1 
ATOM   1856  C  CA   . ILE   A 1 124 ? 15.788  17.342  16.255  1.00 23.18 ? 123 ILE   A CA   1 
ATOM   1857  C  C    . ILE   A 1 124 ? 15.247  16.049  16.866  1.00 26.90 ? 123 ILE   A C    1 
ATOM   1858  O  O    . ILE   A 1 124 ? 15.797  14.962  16.682  1.00 22.96 ? 123 ILE   A O    1 
ATOM   1859  C  CB   . ILE   A 1 124 ? 14.981  17.788  15.028  1.00 20.89 ? 123 ILE   A CB   1 
ATOM   1860  C  CG1  . ILE   A 1 124 ? 15.066  16.735  13.916  1.00 22.90 ? 123 ILE   A CG1  1 
ATOM   1861  C  CG2  . ILE   A 1 124 ? 15.474  19.162  14.510  1.00 24.71 ? 123 ILE   A CG2  1 
ATOM   1862  C  CD1  . ILE   A 1 124 ? 14.208  17.065  12.654  1.00 25.30 ? 123 ILE   A CD1  1 
ATOM   1863  H  H    . ILE   A 1 124 ? 17.366  16.529  15.392  1.00 20.45 ? 123 ILE   A H    1 
ATOM   1864  H  HA   . ILE   A 1 124 ? 15.687  18.030  16.932  1.00 27.81 ? 123 ILE   A HA   1 
ATOM   1865  H  HB   . ILE   A 1 124 ? 14.054  17.879  15.299  1.00 25.06 ? 123 ILE   A HB   1 
ATOM   1866  H  HG12 . ILE   A 1 124 ? 15.990  16.659  13.631  1.00 27.48 ? 123 ILE   A HG12 1 
ATOM   1867  H  HG13 . ILE   A 1 124 ? 14.756  15.886  14.268  1.00 27.48 ? 123 ILE   A HG13 1 
ATOM   1868  H  HG21 . ILE   A 1 124 ? 14.727  19.637  14.113  1.00 29.65 ? 123 ILE   A HG21 1 
ATOM   1869  H  HG22 . ILE   A 1 124 ? 15.832  19.670  15.254  1.00 29.65 ? 123 ILE   A HG22 1 
ATOM   1870  H  HG23 . ILE   A 1 124 ? 16.165  19.018  13.844  1.00 29.65 ? 123 ILE   A HG23 1 
ATOM   1871  H  HD11 . ILE   A 1 124 ? 13.954  16.236  12.219  1.00 30.35 ? 123 ILE   A HD11 1 
ATOM   1872  H  HD12 . ILE   A 1 124 ? 13.415  17.551  12.930  1.00 30.35 ? 123 ILE   A HD12 1 
ATOM   1873  H  HD13 . ILE   A 1 124 ? 14.735  17.609  12.048  1.00 30.35 ? 123 ILE   A HD13 1 
ATOM   1874  N  N    . GLU   A 1 125 ? 14.147  16.189  17.611  1.00 25.31 ? 124 GLU   A N    1 
ATOM   1875  C  CA   . GLU   A 1 125 ? 13.516  15.082  18.333  1.00 25.66 ? 124 GLU   A CA   1 
ATOM   1876  C  C    . GLU   A 1 125 ? 12.517  14.364  17.444  1.00 28.71 ? 124 GLU   A C    1 
ATOM   1877  O  O    . GLU   A 1 125 ? 11.497  14.950  17.055  1.00 26.40 ? 124 GLU   A O    1 
ATOM   1878  C  CB   . GLU   A 1 125 ? 12.796  15.617  19.573  1.00 30.78 ? 124 GLU   A CB   1 
ATOM   1879  C  CG   . GLU   A 1 125 ? 12.306  14.563  20.534  1.00 34.28 ? 124 GLU   A CG   1 
ATOM   1880  C  CD   . GLU   A 1 125 ? 12.049  15.166  21.903  1.00 43.49 ? 124 GLU   A CD   1 
ATOM   1881  O  OE1  . GLU   A 1 125 ? 13.037  15.536  22.602  1.00 45.71 ? 124 GLU   A OE1  1 
ATOM   1882  O  OE2  . GLU   A 1 125 ? 10.858  15.307  22.252  1.00 46.28 ? 124 GLU   A OE2  1 
ATOM   1883  H  H    . GLU   A 1 125 ? 13.736  16.937  17.716  1.00 30.37 ? 124 GLU   A H    1 
ATOM   1884  H  HA   . GLU   A 1 125 ? 14.204  14.447  18.590  1.00 30.79 ? 124 GLU   A HA   1 
ATOM   1885  H  HB2  . GLU   A 1 125 ? 13.409  16.191  20.059  1.00 36.93 ? 124 GLU   A HB2  1 
ATOM   1886  H  HB3  . GLU   A 1 125 ? 12.024  16.127  19.283  1.00 36.93 ? 124 GLU   A HB3  1 
ATOM   1887  H  HG2  . GLU   A 1 125 ? 11.478  14.183  20.203  1.00 41.14 ? 124 GLU   A HG2  1 
ATOM   1888  H  HG3  . GLU   A 1 125 ? 12.978  13.869  20.623  1.00 41.14 ? 124 GLU   A HG3  1 
ATOM   1889  N  N    . LEU   A 1 126 ? 12.814  13.108  17.115  1.00 23.41 ? 125 LEU   A N    1 
ATOM   1890  C  CA   . LEU   A 1 126 ? 12.023  12.309  16.195  1.00 24.05 ? 125 LEU   A CA   1 
ATOM   1891  C  C    . LEU   A 1 126 ? 12.024  10.863  16.674  1.00 25.39 ? 125 LEU   A C    1 
ATOM   1892  O  O    . LEU   A 1 126 ? 13.058  10.357  17.108  1.00 32.87 ? 125 LEU   A O    1 
ATOM   1893  C  CB   . LEU   A 1 126 ? 12.611  12.448  14.781  1.00 29.00 ? 125 LEU   A CB   1 
ATOM   1894  C  CG   . LEU   A 1 126 ? 11.755  12.117  13.570  1.00 35.01 ? 125 LEU   A CG   1 
ATOM   1895  C  CD1  . LEU   A 1 126 ? 10.629  13.094  13.409  1.00 28.99 ? 125 LEU   A CD1  1 
ATOM   1896  C  CD2  . LEU   A 1 126 ? 12.640  12.098  12.302  1.00 32.66 ? 125 LEU   A CD2  1 
ATOM   1897  H  H    . LEU   A 1 126 ? 13.496  12.685  17.425  1.00 28.09 ? 125 LEU   A H    1 
ATOM   1898  H  HA   . LEU   A 1 126 ? 11.096  12.594  16.178  1.00 28.87 ? 125 LEU   A HA   1 
ATOM   1899  H  HB2  . LEU   A 1 126 ? 12.886  13.372  14.673  1.00 34.81 ? 125 LEU   A HB2  1 
ATOM   1900  H  HB3  . LEU   A 1 126 ? 13.385  11.864  14.733  1.00 34.81 ? 125 LEU   A HB3  1 
ATOM   1901  H  HG   . LEU   A 1 126 ? 11.358  11.241  13.696  1.00 42.01 ? 125 LEU   A HG   1 
ATOM   1902  H  HD11 . LEU   A 1 126 ? 10.401  13.160  12.468  1.00 34.78 ? 125 LEU   A HD11 1 
ATOM   1903  H  HD12 . LEU   A 1 126 ? 9.863   12.779  13.914  1.00 34.78 ? 125 LEU   A HD12 1 
ATOM   1904  H  HD13 . LEU   A 1 126 ? 10.912  13.960  13.742  1.00 34.78 ? 125 LEU   A HD13 1 
ATOM   1905  H  HD21 . LEU   A 1 126 ? 12.157  11.655  11.586  1.00 39.19 ? 125 LEU   A HD21 1 
ATOM   1906  H  HD22 . LEU   A 1 126 ? 12.844  13.012  12.046  1.00 39.19 ? 125 LEU   A HD22 1 
ATOM   1907  H  HD23 . LEU   A 1 126 ? 13.460  11.618  12.495  1.00 39.19 ? 125 LEU   A HD23 1 
ATOM   1908  N  N    . LYS   A 1 127 ? 10.858  10.227  16.643  1.00 22.76 ? 126 LYS   A N    1 
ATOM   1909  C  CA   . LYS   A 1 127 ? 10.722  8.808   16.949  1.00 25.74 ? 126 LYS   A CA   1 
ATOM   1910  C  C    . LYS   A 1 127 ? 10.162  8.099   15.723  1.00 24.13 ? 126 LYS   A C    1 
ATOM   1911  O  O    . LYS   A 1 127 ? 9.033   8.363   15.299  1.00 25.83 ? 126 LYS   A O    1 
ATOM   1912  C  CB   . LYS   A 1 127 ? 9.822   8.581   18.170  1.00 31.64 ? 126 LYS   A CB   1 
ATOM   1913  C  CG   . LYS   A 1 127 ? 9.591   7.089   18.512  1.00 38.19 ? 126 LYS   A CG   1 
ATOM   1914  C  CD   . LYS   A 1 127 ? 10.724  6.494   19.339  1.00 54.97 ? 126 LYS   A CD   1 
ATOM   1915  C  CE   . LYS   A 1 127 ? 11.056  5.049   18.951  1.00 54.08 ? 126 LYS   A CE   1 
ATOM   1916  N  NZ   . LYS   A 1 127 ? 12.535  4.800   18.981  1.00 43.54 ? 126 LYS   A NZ   1 
ATOM   1917  H  H    . LYS   A 1 127 ? 10.112  10.607  16.442  1.00 27.31 ? 126 LYS   A H    1 
ATOM   1918  H  HA   . LYS   A 1 127 ? 11.595  8.435   17.148  1.00 30.89 ? 126 LYS   A HA   1 
ATOM   1919  H  HB2  . LYS   A 1 127 ? 10.233  9.001   18.942  1.00 37.97 ? 126 LYS   A HB2  1 
ATOM   1920  H  HB3  . LYS   A 1 127 ? 8.955   8.982   17.997  1.00 37.97 ? 126 LYS   A HB3  1 
ATOM   1921  H  HG2  . LYS   A 1 127 ? 8.770   7.003   19.022  1.00 45.83 ? 126 LYS   A HG2  1 
ATOM   1922  H  HG3  . LYS   A 1 127 ? 9.523   6.582   17.688  1.00 45.83 ? 126 LYS   A HG3  1 
ATOM   1923  H  HD2  . LYS   A 1 127 ? 11.523  7.029   19.210  1.00 65.96 ? 126 LYS   A HD2  1 
ATOM   1924  H  HD3  . LYS   A 1 127 ? 10.468  6.501   20.275  1.00 65.96 ? 126 LYS   A HD3  1 
ATOM   1925  H  HE2  . LYS   A 1 127 ? 10.631  4.442   19.578  1.00 64.90 ? 126 LYS   A HE2  1 
ATOM   1926  H  HE3  . LYS   A 1 127 ? 10.734  4.875   18.053  1.00 64.90 ? 126 LYS   A HE3  1 
ATOM   1927  H  HZ1  . LYS   A 1 127 ? 12.698  3.964   19.236  1.00 52.25 ? 126 LYS   A HZ1  1 
ATOM   1928  H  HZ2  . LYS   A 1 127 ? 12.881  4.928   18.171  1.00 52.25 ? 126 LYS   A HZ2  1 
ATOM   1929  H  HZ3  . LYS   A 1 127 ? 12.926  5.359   19.553  1.00 52.25 ? 126 LYS   A HZ3  1 
ATOM   1930  N  N    . PHE   A 1 128 ? 10.941  7.184   15.164  1.00 24.49 ? 127 PHE   A N    1 
ATOM   1931  C  CA   . PHE   A 1 128 ? 10.471  6.422   14.023  1.00 22.48 ? 127 PHE   A CA   1 
ATOM   1932  C  C    . PHE   A 1 128 ? 9.545   5.274   14.433  1.00 23.48 ? 127 PHE   A C    1 
ATOM   1933  O  O    . PHE   A 1 128 ? 9.706   4.655   15.486  1.00 26.71 ? 127 PHE   A O    1 
ATOM   1934  C  CB   . PHE   A 1 128 ? 11.667  5.883   13.251  1.00 21.78 ? 127 PHE   A CB   1 
ATOM   1935  C  CG   . PHE   A 1 128 ? 12.410  6.926   12.493  1.00 22.55 ? 127 PHE   A CG   1 
ATOM   1936  C  CD1  . PHE   A 1 128 ? 11.828  7.555   11.419  1.00 22.67 ? 127 PHE   A CD1  1 
ATOM   1937  C  CD2  . PHE   A 1 128 ? 13.694  7.279   12.858  1.00 23.89 ? 127 PHE   A CD2  1 
ATOM   1938  C  CE1  . PHE   A 1 128 ? 12.515  8.521   10.722  1.00 24.53 ? 127 PHE   A CE1  1 
ATOM   1939  C  CE2  . PHE   A 1 128 ? 14.386  8.215   12.160  1.00 24.93 ? 127 PHE   A CE2  1 
ATOM   1940  C  CZ   . PHE   A 1 128 ? 13.805  8.846   11.104  1.00 22.02 ? 127 PHE   A CZ   1 
ATOM   1941  H  H    . PHE   A 1 128 ? 11.737  6.989   15.425  1.00 29.39 ? 127 PHE   A H    1 
ATOM   1942  H  HA   . PHE   A 1 128 ? 9.950   7.000   13.444  1.00 26.98 ? 127 PHE   A HA   1 
ATOM   1943  H  HB2  . PHE   A 1 128 ? 12.285  5.475   13.878  1.00 26.14 ? 127 PHE   A HB2  1 
ATOM   1944  H  HB3  . PHE   A 1 128 ? 11.355  5.220   12.614  1.00 26.14 ? 127 PHE   A HB3  1 
ATOM   1945  H  HD1  . PHE   A 1 128 ? 10.964  7.326   11.162  1.00 27.20 ? 127 PHE   A HD1  1 
ATOM   1946  H  HD2  . PHE   A 1 128 ? 14.091  6.868   13.592  1.00 28.67 ? 127 PHE   A HD2  1 
ATOM   1947  H  HE1  . PHE   A 1 128 ? 12.116  8.953   10.001  1.00 29.43 ? 127 PHE   A HE1  1 
ATOM   1948  H  HE2  . PHE   A 1 128 ? 15.258  8.426   12.404  1.00 29.92 ? 127 PHE   A HE2  1 
ATOM   1949  H  HZ   . PHE   A 1 128 ? 14.276  9.498   10.638  1.00 26.43 ? 127 PHE   A HZ   1 
ATOM   1950  N  N    . ASN   A 1 129 ? 8.580   4.995   13.573  1.00 23.85 ? 128 ASN   A N    1 
ATOM   1951  C  CA   . ASN   A 1 129 ? 7.700   3.864   13.795  1.00 28.41 ? 128 ASN   A CA   1 
ATOM   1952  C  C    . ASN   A 1 129 ? 8.274   2.541   13.297  1.00 27.39 ? 128 ASN   A C    1 
ATOM   1953  O  O    . ASN   A 1 129 ? 8.224   1.558   14.047  1.00 26.37 ? 128 ASN   A O    1 
ATOM   1954  C  CB   . ASN   A 1 129 ? 6.337   4.158   13.170  1.00 27.13 ? 128 ASN   A CB   1 
ATOM   1955  C  CG   . ASN   A 1 129 ? 5.618   5.267   13.909  1.00 26.66 ? 128 ASN   A CG   1 
ATOM   1956  O  OD1  . ASN   A 1 129 ? 5.747   5.368   15.113  1.00 29.93 ? 128 ASN   A OD1  1 
ATOM   1957  N  ND2  . ASN   A 1 129 ? 4.845   6.074   13.199  1.00 30.46 ? 128 ASN   A ND2  1 
ATOM   1958  H  H    . ASN   A 1 129 ? 8.416   5.444   12.858  1.00 28.61 ? 128 ASN   A H    1 
ATOM   1959  H  HA   . ASN   A 1 129 ? 7.601   3.739   14.752  1.00 34.10 ? 128 ASN   A HA   1 
ATOM   1960  H  HB2  . ASN   A 1 129 ? 6.460   4.434   12.248  1.00 32.56 ? 128 ASN   A HB2  1 
ATOM   1961  H  HB3  . ASN   A 1 129 ? 5.788   3.359   13.208  1.00 32.56 ? 128 ASN   A HB3  1 
ATOM   1962  H  HD21 . ASN   A 1 129 ? 4.422   6.714   13.586  1.00 36.55 ? 128 ASN   A HD21 1 
ATOM   1963  H  HD22 . ASN   A 1 129 ? 4.766   5.957   12.350  1.00 36.55 ? 128 ASN   A HD22 1 
ATOM   1964  N  N    . PRO   A 1 130 ? 8.825   2.435   12.092  1.00 24.62 ? 129 PRO   A N    1 
ATOM   1965  C  CA   . PRO   A 1 130 ? 9.393   1.134   11.669  1.00 20.98 ? 129 PRO   A CA   1 
ATOM   1966  C  C    . PRO   A 1 130 ? 10.585  0.744   12.517  1.00 22.87 ? 129 PRO   A C    1 
ATOM   1967  O  O    . PRO   A 1 130 ? 11.555  1.506   12.635  1.00 25.82 ? 129 PRO   A O    1 
ATOM   1968  C  CB   . PRO   A 1 130 ? 9.813   1.368   10.206  1.00 24.05 ? 129 PRO   A CB   1 
ATOM   1969  C  CG   . PRO   A 1 130 ? 9.084   2.605   9.782   1.00 23.05 ? 129 PRO   A CG   1 
ATOM   1970  C  CD   . PRO   A 1 130 ? 8.960   3.448   11.024  1.00 22.76 ? 129 PRO   A CD   1 
ATOM   1971  H  HA   . PRO   A 1 130 ? 8.714   0.442   11.712  1.00 25.18 ? 129 PRO   A HA   1 
ATOM   1972  H  HB2  . PRO   A 1 130 ? 10.773  1.498   10.156  1.00 28.86 ? 129 PRO   A HB2  1 
ATOM   1973  H  HB3  . PRO   A 1 130 ? 9.552   0.609   9.662   1.00 28.86 ? 129 PRO   A HB3  1 
ATOM   1974  H  HG2  . PRO   A 1 130 ? 9.594   3.070   9.100   1.00 27.67 ? 129 PRO   A HG2  1 
ATOM   1975  H  HG3  . PRO   A 1 130 ? 8.208   2.368   9.438   1.00 27.67 ? 129 PRO   A HG3  1 
ATOM   1976  H  HD2  . PRO   A 1 130 ? 9.753   3.989   11.157  1.00 27.31 ? 129 PRO   A HD2  1 
ATOM   1977  H  HD3  . PRO   A 1 130 ? 8.174   4.015   10.982  1.00 27.31 ? 129 PRO   A HD3  1 
ATOM   1978  N  N    . PRO   A 1 131 ? 10.555  -0.444  13.134  1.00 24.41 ? 130 PRO   A N    1 
ATOM   1979  C  CA   . PRO   A 1 131 ? 11.729  -0.895  13.894  1.00 22.13 ? 130 PRO   A CA   1 
ATOM   1980  C  C    . PRO   A 1 131 ? 13.031  -0.795  13.099  1.00 19.82 ? 130 PRO   A C    1 
ATOM   1981  O  O    . PRO   A 1 131 ? 14.075  -0.489  13.669  1.00 22.76 ? 130 PRO   A O    1 
ATOM   1982  C  CB   . PRO   A 1 131 ? 11.385  -2.358  14.244  1.00 24.01 ? 130 PRO   A CB   1 
ATOM   1983  C  CG   . PRO   A 1 131 ? 9.878   -2.391  14.244  1.00 26.47 ? 130 PRO   A CG   1 
ATOM   1984  C  CD   . PRO   A 1 131 ? 9.436   -1.405  13.190  1.00 25.78 ? 130 PRO   A CD   1 
ATOM   1985  H  HA   . PRO   A 1 131 ? 11.811  -0.385  14.716  1.00 26.56 ? 130 PRO   A HA   1 
ATOM   1986  H  HB2  . PRO   A 1 131 ? 11.748  -2.956  13.573  1.00 28.81 ? 130 PRO   A HB2  1 
ATOM   1987  H  HB3  . PRO   A 1 131 ? 11.740  -2.585  15.118  1.00 28.81 ? 130 PRO   A HB3  1 
ATOM   1988  H  HG2  . PRO   A 1 131 ? 9.571   -3.285  14.027  1.00 31.76 ? 130 PRO   A HG2  1 
ATOM   1989  H  HG3  . PRO   A 1 131 ? 9.546   -2.130  15.117  1.00 31.76 ? 130 PRO   A HG3  1 
ATOM   1990  H  HD2  . PRO   A 1 131 ? 9.316   -1.846  12.334  1.00 30.93 ? 130 PRO   A HD2  1 
ATOM   1991  H  HD3  . PRO   A 1 131 ? 8.614   -0.963  13.454  1.00 30.93 ? 130 PRO   A HD3  1 
ATOM   1992  N  N    . ALA   A 1 132 ? 12.997  -1.024  11.787  1.00 23.47 ? 131 ALA   A N    1 
ATOM   1993  C  CA   . ALA   A 1 132 ? 14.221  -0.922  10.988  1.00 22.52 ? 131 ALA   A CA   1 
ATOM   1994  C  C    . ALA   A 1 132 ? 14.852  0.464   11.107  1.00 22.45 ? 131 ALA   A C    1 
ATOM   1995  O  O    . ALA   A 1 132 ? 16.073  0.595   11.253  1.00 19.46 ? 131 ALA   A O    1 
ATOM   1996  C  CB   . ALA   A 1 132 ? 13.903  -1.244  9.538   1.00 20.59 ? 131 ALA   A CB   1 
ATOM   1997  H  H    . ALA   A 1 132 ? 12.293  -1.237  11.341  1.00 28.17 ? 131 ALA   A H    1 
ATOM   1998  H  HA   . ALA   A 1 132 ? 14.868  -1.567  11.313  1.00 27.03 ? 131 ALA   A HA   1 
ATOM   1999  H  HB1  . ALA   A 1 132 ? 14.734  -1.356  9.050   1.00 24.71 ? 131 ALA   A HB1  1 
ATOM   2000  H  HB2  . ALA   A 1 132 ? 13.386  -2.065  9.502   1.00 24.71 ? 131 ALA   A HB2  1 
ATOM   2001  H  HB3  . ALA   A 1 132 ? 13.391  -0.514  9.156   1.00 24.71 ? 131 ALA   A HB3  1 
ATOM   2002  N  N    . LEU   A 1 133 ? 14.031  1.508   11.054  1.00 21.23 ? 132 LEU   A N    1 
ATOM   2003  C  CA   . LEU   A 1 133 ? 14.548  2.870   11.177  1.00 23.05 ? 132 LEU   A CA   1 
ATOM   2004  C  C    . LEU   A 1 133 ? 14.940  3.184   12.617  1.00 22.08 ? 132 LEU   A C    1 
ATOM   2005  O  O    . LEU   A 1 133 ? 15.964  3.834   12.862  1.00 21.23 ? 132 LEU   A O    1 
ATOM   2006  C  CB   . LEU   A 1 133 ? 13.510  3.866   10.675  1.00 20.90 ? 132 LEU   A CB   1 
ATOM   2007  C  CG   . LEU   A 1 133 ? 13.326  3.933   9.161   1.00 22.72 ? 132 LEU   A CG   1 
ATOM   2008  C  CD1  . LEU   A 1 133 ? 12.168  4.824   8.752   1.00 22.12 ? 132 LEU   A CD1  1 
ATOM   2009  C  CD2  . LEU   A 1 133 ? 14.635  4.411   8.477   1.00 24.76 ? 132 LEU   A CD2  1 
ATOM   2010  H  H    . LEU   A 1 133 ? 13.179  1.458   10.949  1.00 25.48 ? 132 LEU   A H    1 
ATOM   2011  H  HA   . LEU   A 1 133 ? 15.341  2.956   10.626  1.00 27.66 ? 132 LEU   A HA   1 
ATOM   2012  H  HB2  . LEU   A 1 133 ? 12.652  3.629   11.059  1.00 25.08 ? 132 LEU   A HB2  1 
ATOM   2013  H  HB3  . LEU   A 1 133 ? 13.773  4.752   10.972  1.00 25.08 ? 132 LEU   A HB3  1 
ATOM   2014  H  HG   . LEU   A 1 133 ? 13.113  3.038   8.855   1.00 27.26 ? 132 LEU   A HG   1 
ATOM   2015  H  HD11 . LEU   A 1 133 ? 11.889  4.587   7.854   1.00 26.54 ? 132 LEU   A HD11 1 
ATOM   2016  H  HD12 . LEU   A 1 133 ? 11.434  4.694   9.373   1.00 26.54 ? 132 LEU   A HD12 1 
ATOM   2017  H  HD13 . LEU   A 1 133 ? 12.459  5.750   8.774   1.00 26.54 ? 132 LEU   A HD13 1 
ATOM   2018  H  HD21 . LEU   A 1 133 ? 14.409  4.916   7.680   1.00 29.71 ? 132 LEU   A HD21 1 
ATOM   2019  H  HD22 . LEU   A 1 133 ? 15.128  4.973   9.096   1.00 29.71 ? 132 LEU   A HD22 1 
ATOM   2020  H  HD23 . LEU   A 1 133 ? 15.167  3.636   8.238   1.00 29.71 ? 132 LEU   A HD23 1 
ATOM   2021  N  N    . GLN   A 1 134 ? 14.141  2.732   13.586  1.00 21.37 ? 133 GLN   A N    1 
ATOM   2022  C  CA   . GLN   A 1 134 ? 14.530  2.917   14.976  1.00 24.43 ? 133 GLN   A CA   1 
ATOM   2023  C  C    . GLN   A 1 134 ? 15.928  2.356   15.235  1.00 23.93 ? 133 GLN   A C    1 
ATOM   2024  O  O    . GLN   A 1 134 ? 16.788  3.027   15.819  1.00 23.79 ? 133 GLN   A O    1 
ATOM   2025  C  CB   . GLN   A 1 134 ? 13.540  2.223   15.914  1.00 27.54 ? 133 GLN   A CB   1 
ATOM   2026  C  CG   . GLN   A 1 134 ? 12.140  2.785   15.974  1.00 26.80 ? 133 GLN   A CG   1 
ATOM   2027  C  CD   . GLN   A 1 134 ? 11.216  1.881   16.828  1.00 37.18 ? 133 GLN   A CD   1 
ATOM   2028  O  OE1  . GLN   A 1 134 ? 11.669  0.915   17.437  1.00 38.03 ? 133 GLN   A OE1  1 
ATOM   2029  N  NE2  . GLN   A 1 134 ? 9.952   2.235   16.912  1.00 33.96 ? 133 GLN   A NE2  1 
ATOM   2030  H  H    . GLN   A 1 134 ? 13.392  2.327   13.464  1.00 25.64 ? 133 GLN   A H    1 
ATOM   2031  H  HA   . GLN   A 1 134 ? 14.521  3.869   15.161  1.00 29.31 ? 133 GLN   A HA   1 
ATOM   2032  H  HB2  . GLN   A 1 134 ? 13.460  1.298   15.632  1.00 33.04 ? 133 GLN   A HB2  1 
ATOM   2033  H  HB3  . GLN   A 1 134 ? 13.900  2.265   16.814  1.00 33.04 ? 133 GLN   A HB3  1 
ATOM   2034  H  HG2  . GLN   A 1 134 ? 12.164  3.668   16.377  1.00 32.16 ? 133 GLN   A HG2  1 
ATOM   2035  H  HG3  . GLN   A 1 134 ? 11.775  2.840   15.077  1.00 32.16 ? 133 GLN   A HG3  1 
ATOM   2036  H  HE21 . GLN   A 1 134 ? 9.675   2.940   16.504  1.00 40.75 ? 133 GLN   A HE21 1 
ATOM   2037  H  HE22 . GLN   A 1 134 ? 9.403   1.762   17.375  1.00 40.75 ? 133 GLN   A HE22 1 
ATOM   2038  N  N    . ASP   A 1 135 ? 16.142  1.085   14.855  1.00 21.84 ? 134 ASP   A N    1 
ATOM   2039  C  CA   . ASP   A 1 135 ? 17.406  0.415   15.139  1.00 21.95 ? 134 ASP   A CA   1 
ATOM   2040  C  C    . ASP   A 1 135 ? 18.560  1.085   14.414  1.00 23.65 ? 134 ASP   A C    1 
ATOM   2041  O  O    . ASP   A 1 135 ? 19.622  1.312   15.001  1.00 23.57 ? 134 ASP   A O    1 
ATOM   2042  C  CB   . ASP   A 1 135 ? 17.338  -1.067  14.736  1.00 25.77 ? 134 ASP   A CB   1 
ATOM   2043  C  CG   . ASP   A 1 135 ? 16.344  -1.878  15.574  1.00 27.88 ? 134 ASP   A CG   1 
ATOM   2044  O  OD1  . ASP   A 1 135 ? 15.902  -1.387  16.620  1.00 25.95 ? 134 ASP   A OD1  1 
ATOM   2045  O  OD2  . ASP   A 1 135 ? 15.990  -3.000  15.163  1.00 27.89 ? 134 ASP   A OD2  1 
ATOM   2046  H  H    . ASP   A 1 135 ? 15.571  0.598   14.435  1.00 26.21 ? 134 ASP   A H    1 
ATOM   2047  H  HA   . ASP   A 1 135 ? 17.561  0.467   16.095  1.00 26.33 ? 134 ASP   A HA   1 
ATOM   2048  H  HB2  . ASP   A 1 135 ? 17.064  -1.128  13.808  1.00 30.92 ? 134 ASP   A HB2  1 
ATOM   2049  H  HB3  . ASP   A 1 135 ? 18.216  -1.464  14.850  1.00 30.92 ? 134 ASP   A HB3  1 
ATOM   2050  N  N    . ALA   A 1 136 ? 18.380  1.367   13.109  1.00 23.66 ? 135 ALA   A N    1 
ATOM   2051  C  CA   . ALA   A 1 136 ? 19.466  1.943   12.310  1.00 19.80 ? 135 ALA   A CA   1 
ATOM   2052  C  C    . ALA   A 1 136 ? 19.788  3.381   12.730  1.00 20.36 ? 135 ALA   A C    1 
ATOM   2053  O  O    . ALA   A 1 136 ? 20.951  3.800   12.644  1.00 22.23 ? 135 ALA   A O    1 
ATOM   2054  C  CB   . ALA   A 1 136 ? 19.115  1.901   10.827  1.00 21.11 ? 135 ALA   A CB   1 
ATOM   2055  H  H    . ALA   A 1 136 ? 17.650  1.234   12.674  1.00 28.39 ? 135 ALA   A H    1 
ATOM   2056  H  HA   . ALA   A 1 136 ? 20.261  1.404   12.449  1.00 23.76 ? 135 ALA   A HA   1 
ATOM   2057  H  HB1  . ALA   A 1 136 ? 19.890  2.171   10.311  1.00 25.33 ? 135 ALA   A HB1  1 
ATOM   2058  H  HB2  . ALA   A 1 136 ? 18.858  0.996   10.589  1.00 25.33 ? 135 ALA   A HB2  1 
ATOM   2059  H  HB3  . ALA   A 1 136 ? 18.378  2.509   10.660  1.00 25.33 ? 135 ALA   A HB3  1 
ATOM   2060  N  N    . TYR   A 1 137 ? 18.778  4.138   13.178  1.00 22.16 ? 136 TYR   A N    1 
ATOM   2061  C  CA   . TYR   A 1 137 ? 18.984  5.524   13.635  1.00 21.37 ? 136 TYR   A CA   1 
ATOM   2062  C  C    . TYR   A 1 137 ? 19.809  5.557   14.901  1.00 25.14 ? 136 TYR   A C    1 
ATOM   2063  O  O    . TYR   A 1 137 ? 20.770  6.326   15.010  1.00 22.77 ? 136 TYR   A O    1 
ATOM   2064  C  CB   . TYR   A 1 137 ? 17.605  6.169   13.822  1.00 21.58 ? 136 TYR   A CB   1 
ATOM   2065  C  CG   . TYR   A 1 137 ? 17.433  7.615   14.269  1.00 28.93 ? 136 TYR   A CG   1 
ATOM   2066  C  CD1  . TYR   A 1 137 ? 18.313  8.634   13.904  1.00 32.08 ? 136 TYR   A CD1  1 
ATOM   2067  C  CD2  . TYR   A 1 137 ? 16.288  7.962   15.001  1.00 30.25 ? 136 TYR   A CD2  1 
ATOM   2068  C  CE1  . TYR   A 1 137 ? 18.064  9.978   14.317  1.00 31.82 ? 136 TYR   A CE1  1 
ATOM   2069  C  CE2  . TYR   A 1 137 ? 16.038  9.258   15.402  1.00 33.60 ? 136 TYR   A CE2  1 
ATOM   2070  C  CZ   . TYR   A 1 137 ? 16.906  10.267  15.054  1.00 37.30 ? 136 TYR   A CZ   1 
ATOM   2071  O  OH   . TYR   A 1 137 ? 16.578  11.549  15.480  1.00 35.74 ? 136 TYR   A OH   1 
ATOM   2072  H  H    . TYR   A 1 137 ? 17.960  3.876   13.228  1.00 26.59 ? 136 TYR   A H    1 
ATOM   2073  H  HA   . TYR   A 1 137 ? 19.473  6.040   12.975  1.00 25.65 ? 136 TYR   A HA   1 
ATOM   2074  H  HB2  . TYR   A 1 137 ? 17.152  6.108   12.967  1.00 25.90 ? 136 TYR   A HB2  1 
ATOM   2075  H  HB3  . TYR   A 1 137 ? 17.138  5.637   14.485  1.00 25.90 ? 136 TYR   A HB3  1 
ATOM   2076  H  HD1  . TYR   A 1 137 ? 19.063  8.438   13.390  1.00 38.50 ? 136 TYR   A HD1  1 
ATOM   2077  H  HD2  . TYR   A 1 137 ? 15.678  7.296   15.224  1.00 36.31 ? 136 TYR   A HD2  1 
ATOM   2078  H  HE1  . TYR   A 1 137 ? 18.663  10.655  14.099  1.00 38.18 ? 136 TYR   A HE1  1 
ATOM   2079  H  HE2  . TYR   A 1 137 ? 15.281  9.450   15.907  1.00 40.32 ? 136 TYR   A HE2  1 
ATOM   2080  H  HH   . TYR   A 1 137 ? 15.780  11.568  15.744  1.00 42.89 ? 136 TYR   A HH   1 
ATOM   2081  N  N    . TYR   A 1 138 ? 19.496  4.667   15.840  1.00 22.21 ? 137 TYR   A N    1 
ATOM   2082  C  CA   . TYR   A 1 138 ? 20.298  4.558   17.049  1.00 26.46 ? 137 TYR   A CA   1 
ATOM   2083  C  C    . TYR   A 1 138 ? 21.749  4.253   16.730  1.00 20.97 ? 137 TYR   A C    1 
ATOM   2084  O  O    . TYR   A 1 138 ? 22.657  4.879   17.285  1.00 26.19 ? 137 TYR   A O    1 
ATOM   2085  C  CB   . TYR   A 1 138 ? 19.689  3.475   17.931  1.00 32.20 ? 137 TYR   A CB   1 
ATOM   2086  C  CG   . TYR   A 1 138 ? 20.390  3.204   19.220  1.00 31.14 ? 137 TYR   A CG   1 
ATOM   2087  C  CD1  . TYR   A 1 138 ? 21.389  2.244   19.300  1.00 38.34 ? 137 TYR   A CD1  1 
ATOM   2088  C  CD2  . TYR   A 1 138 ? 20.034  3.889   20.381  1.00 37.99 ? 137 TYR   A CD2  1 
ATOM   2089  C  CE1  . TYR   A 1 138 ? 22.022  1.971   20.516  1.00 45.32 ? 137 TYR   A CE1  1 
ATOM   2090  C  CE2  . TYR   A 1 138 ? 20.656  3.622   21.580  1.00 44.15 ? 137 TYR   A CE2  1 
ATOM   2091  C  CZ   . TYR   A 1 138 ? 21.653  2.667   21.640  1.00 44.25 ? 137 TYR   A CZ   1 
ATOM   2092  O  OH   . TYR   A 1 138 ? 22.279  2.403   22.842  1.00 57.77 ? 137 TYR   A OH   1 
ATOM   2093  H  H    . TYR   A 1 138 ? 18.832  4.122   15.800  1.00 26.65 ? 137 TYR   A H    1 
ATOM   2094  H  HA   . TYR   A 1 138 ? 20.287  5.400   17.531  1.00 31.75 ? 137 TYR   A HA   1 
ATOM   2095  H  HB2  . TYR   A 1 138 ? 18.781  3.738   18.150  1.00 38.64 ? 137 TYR   A HB2  1 
ATOM   2096  H  HB3  . TYR   A 1 138 ? 19.683  2.645   17.430  1.00 38.64 ? 137 TYR   A HB3  1 
ATOM   2097  H  HD1  . TYR   A 1 138 ? 21.640  1.776   18.537  1.00 46.01 ? 137 TYR   A HD1  1 
ATOM   2098  H  HD2  . TYR   A 1 138 ? 19.366  4.536   20.345  1.00 45.59 ? 137 TYR   A HD2  1 
ATOM   2099  H  HE1  . TYR   A 1 138 ? 22.688  1.323   20.563  1.00 54.39 ? 137 TYR   A HE1  1 
ATOM   2100  H  HE2  . TYR   A 1 138 ? 20.406  4.083   22.348  1.00 52.98 ? 137 TYR   A HE2  1 
ATOM   2101  H  HH   . TYR   A 1 138 ? 21.835  2.730   23.475  1.00 69.33 ? 137 TYR   A HH   1 
ATOM   2102  N  N    . ARG   A 1 139 ? 21.991  3.314   15.815  1.00 21.83 ? 138 ARG   A N    1 
ATOM   2103  C  CA   . ARG   A 1 139 ? 23.361  3.022   15.439  1.00 25.76 ? 138 ARG   A CA   1 
ATOM   2104  C  C    . ARG   A 1 139 ? 23.993  4.228   14.761  1.00 23.16 ? 138 ARG   A C    1 
ATOM   2105  O  O    . ARG   A 1 139 ? 25.164  4.537   14.998  1.00 23.66 ? 138 ARG   A O    1 
ATOM   2106  C  CB   . ARG   A 1 139 ? 23.405  1.812   14.506  1.00 28.58 ? 138 ARG   A CB   1 
ATOM   2107  C  CG   . ARG   A 1 139 ? 23.127  0.476   15.212  1.00 35.90 ? 138 ARG   A CG   1 
ATOM   2108  C  CD   . ARG   A 1 139 ? 23.664  -0.720  14.398  1.00 47.50 ? 138 ARG   A CD   1 
ATOM   2109  N  NE   . ARG   A 1 139 ? 25.054  -0.577  13.965  1.00 53.84 ? 138 ARG   A NE   1 
ATOM   2110  C  CZ   . ARG   A 1 139 ? 25.709  -1.475  13.240  1.00 57.79 ? 138 ARG   A CZ   1 
ATOM   2111  N  NH1  . ARG   A 1 139 ? 25.078  -2.470  12.636  1.00 61.93 ? 138 ARG   A NH1  1 
ATOM   2112  N  NH2  . ARG   A 1 139 ? 27.029  -1.361  13.097  1.00 55.43 ? 138 ARG   A NH2  1 
ATOM   2113  H  H    . ARG   A 1 139 ? 21.392  2.847   15.411  1.00 26.20 ? 138 ARG   A H    1 
ATOM   2114  H  HA   . ARG   A 1 139 ? 23.870  2.805   16.236  1.00 30.91 ? 138 ARG   A HA   1 
ATOM   2115  H  HB2  . ARG   A 1 139 ? 22.735  1.927   13.815  1.00 34.29 ? 138 ARG   A HB2  1 
ATOM   2116  H  HB3  . ARG   A 1 139 ? 24.288  1.758   14.107  1.00 34.29 ? 138 ARG   A HB3  1 
ATOM   2117  H  HG2  . ARG   A 1 139 ? 23.564  0.474   16.079  1.00 43.08 ? 138 ARG   A HG2  1 
ATOM   2118  H  HG3  . ARG   A 1 139 ? 22.170  0.364   15.323  1.00 43.08 ? 138 ARG   A HG3  1 
ATOM   2119  H  HD2  . ARG   A 1 139 ? 23.608  -1.519  14.946  1.00 57.01 ? 138 ARG   A HD2  1 
ATOM   2120  H  HD3  . ARG   A 1 139 ? 23.118  -0.824  13.603  1.00 57.01 ? 138 ARG   A HD3  1 
ATOM   2121  H  HE   . ARG   A 1 139 ? 25.475  0.137   14.196  1.00 64.60 ? 138 ARG   A HE   1 
ATOM   2122  H  HH11 . ARG   A 1 139 ? 25.522  -3.041  12.170  1.00 74.31 ? 138 ARG   A HH11 1 
ATOM   2123  H  HH12 . ARG   A 1 139 ? 24.225  -2.545  12.708  1.00 74.31 ? 138 ARG   A HH12 1 
ATOM   2124  H  HH21 . ARG   A 1 139 ? 27.462  -1.938  12.629  1.00 66.51 ? 138 ARG   A HH21 1 
ATOM   2125  H  HH22 . ARG   A 1 139 ? 27.447  -0.710  13.473  1.00 66.51 ? 138 ARG   A HH22 1 
ATOM   2126  N  N    . ALA   A 1 140 ? 23.225  4.914   13.914  1.00 20.94 ? 139 ALA   A N    1 
ATOM   2127  C  CA   . ALA   A 1 140 ? 23.772  6.040   13.158  1.00 20.51 ? 139 ALA   A CA   1 
ATOM   2128  C  C    . ALA   A 1 140 ? 24.193  7.170   14.087  1.00 24.55 ? 139 ALA   A C    1 
ATOM   2129  O  O    . ALA   A 1 140 ? 25.225  7.820   13.862  1.00 21.73 ? 139 ALA   A O    1 
ATOM   2130  C  CB   . ALA   A 1 140 ? 22.742  6.535   12.128  1.00 21.13 ? 139 ALA   A CB   1 
ATOM   2131  H  H    . ALA   A 1 140 ? 22.395  4.751   13.760  1.00 25.12 ? 139 ALA   A H    1 
ATOM   2132  H  HA   . ALA   A 1 140 ? 24.558  5.743   12.672  1.00 24.61 ? 139 ALA   A HA   1 
ATOM   2133  H  HB1  . ALA   A 1 140 ? 23.035  7.388   11.773  1.00 25.36 ? 139 ALA   A HB1  1 
ATOM   2134  H  HB2  . ALA   A 1 140 ? 22.673  5.884   11.412  1.00 25.36 ? 139 ALA   A HB2  1 
ATOM   2135  H  HB3  . ALA   A 1 140 ? 21.882  6.637   12.566  1.00 25.36 ? 139 ALA   A HB3  1 
ATOM   2136  N  N    . ARG   A 1 141 ? 23.421  7.401   15.143  1.00 23.20 ? 140 ARG   A N    1 
ATOM   2137  C  CA   . ARG   A 1 141 ? 23.733  8.460   16.102  1.00 26.86 ? 140 ARG   A CA   1 
ATOM   2138  C  C    . ARG   A 1 141 ? 25.076  8.213   16.789  1.00 31.67 ? 140 ARG   A C    1 
ATOM   2139  O  O    . ARG   A 1 141 ? 25.787  9.151   17.149  1.00 32.05 ? 140 ARG   A O    1 
ATOM   2140  C  CB   . ARG   A 1 141 ? 22.631  8.558   17.157  1.00 28.88 ? 140 ARG   A CB   1 
ATOM   2141  C  CG   . ARG   A 1 141 ? 21.304  9.069   16.622  1.00 32.66 ? 140 ARG   A CG   1 
ATOM   2142  C  CD   . ARG   A 1 141 ? 20.329  9.359   17.750  1.00 43.71 ? 140 ARG   A CD   1 
ATOM   2143  N  NE   . ARG   A 1 141 ? 20.413  10.745  18.201  1.00 41.95 ? 140 ARG   A NE   1 
ATOM   2144  C  CZ   . ARG   A 1 141 ? 19.365  11.552  18.331  1.00 35.70 ? 140 ARG   A CZ   1 
ATOM   2145  N  NH1  . ARG   A 1 141 ? 18.147  11.111  18.047  1.00 43.27 ? 140 ARG   A NH1  1 
ATOM   2146  N  NH2  . ARG   A 1 141 ? 19.534  12.799  18.747  1.00 30.25 ? 140 ARG   A NH2  1 
ATOM   2147  H  H    . ARG   A 1 141 ? 22.708  6.959   15.330  1.00 27.84 ? 140 ARG   A H    1 
ATOM   2148  H  HA   . ARG   A 1 141 ? 23.783  9.318   15.632  1.00 32.23 ? 140 ARG   A HA   1 
ATOM   2149  H  HB2  . ARG   A 1 141 ? 22.477  7.676   17.532  1.00 34.65 ? 140 ARG   A HB2  1 
ATOM   2150  H  HB3  . ARG   A 1 141 ? 22.921  9.165   17.856  1.00 34.65 ? 140 ARG   A HB3  1 
ATOM   2151  H  HG2  . ARG   A 1 141 ? 21.452  9.892   16.130  1.00 39.19 ? 140 ARG   A HG2  1 
ATOM   2152  H  HG3  . ARG   A 1 141 ? 20.910  8.397   16.043  1.00 39.19 ? 140 ARG   A HG3  1 
ATOM   2153  H  HD2  . ARG   A 1 141 ? 19.425  9.197   17.438  1.00 52.46 ? 140 ARG   A HD2  1 
ATOM   2154  H  HD3  . ARG   A 1 141 ? 20.532  8.782   18.504  1.00 52.46 ? 140 ARG   A HD3  1 
ATOM   2155  H  HE   . ARG   A 1 141 ? 21.275  11.070  18.504  1.00 50.34 ? 140 ARG   A HE   1 
ATOM   2156  H  HH11 . ARG   A 1 141 ? 18.035  10.302  17.777  1.00 51.93 ? 140 ARG   A HH11 1 
ATOM   2157  H  HH12 . ARG   A 1 141 ? 17.469  11.634  18.132  1.00 51.93 ? 140 ARG   A HH12 1 
ATOM   2158  H  HH21 . ARG   A 1 141 ? 20.323  13.087  18.933  1.00 36.30 ? 140 ARG   A HH21 1 
ATOM   2159  H  HH22 . ARG   A 1 141 ? 18.855  13.319  18.832  1.00 36.30 ? 140 ARG   A HH22 1 
ATOM   2160  N  N    . ALA   A 1 142 ? 25.409  6.939   16.962  1.00 28.71 ? 141 ALA   A N    1 
ATOM   2161  C  CA   . ALA   A 1 142 ? 26.638  6.520   17.601  1.00 32.99 ? 141 ALA   A CA   1 
ATOM   2162  C  C    . ALA   A 1 142 ? 27.800  6.418   16.635  1.00 32.28 ? 141 ALA   A C    1 
ATOM   2163  O  O    . ALA   A 1 142 ? 28.893  6.058   17.061  1.00 33.38 ? 141 ALA   A O    1 
ATOM   2164  C  CB   . ALA   A 1 142 ? 26.444  5.161   18.279  1.00 36.23 ? 141 ALA   A CB   1 
ATOM   2165  H  H    . ALA   A 1 142 ? 24.928  6.277   16.696  1.00 34.46 ? 141 ALA   A H    1 
ATOM   2166  H  HA   . ALA   A 1 142 ? 26.862  7.173   18.282  1.00 39.58 ? 141 ALA   A HA   1 
ATOM   2167  H  HB1  . ALA   A 1 142 ? 27.070  5.083   19.016  1.00 43.47 ? 141 ALA   A HB1  1 
ATOM   2168  H  HB2  . ALA   A 1 142 ? 25.534  5.100   18.609  1.00 43.47 ? 141 ALA   A HB2  1 
ATOM   2169  H  HB3  . ALA   A 1 142 ? 26.608  4.458   17.630  1.00 43.47 ? 141 ALA   A HB3  1 
ATOM   2170  N  N    . GLY   A 1 143 ? 27.590  6.669   15.341  1.00 28.04 ? 142 GLY   A N    1 
ATOM   2171  C  CA   . GLY   A 1 143 ? 28.667  6.695   14.364  1.00 23.52 ? 142 GLY   A CA   1 
ATOM   2172  C  C    . GLY   A 1 143 ? 28.592  5.626   13.292  1.00 22.10 ? 142 GLY   A C    1 
ATOM   2173  O  O    . GLY   A 1 143 ? 29.360  5.691   12.315  1.00 28.42 ? 142 GLY   A O    1 
ATOM   2174  H  H    . GLY   A 1 143 ? 26.816  6.830   15.004  1.00 33.65 ? 142 GLY   A H    1 
ATOM   2175  H  HA2  . GLY   A 1 143 ? 28.661  7.558   13.921  1.00 28.23 ? 142 GLY   A HA2  1 
ATOM   2176  H  HA3  . GLY   A 1 143 ? 29.510  6.586   14.831  1.00 28.23 ? 142 GLY   A HA3  1 
ATOM   2177  N  N    . GLU   A 1 144 ? 27.707  4.640   13.413  1.00 25.52 ? 143 GLU   A N    1 
ATOM   2178  C  CA   . GLU   A 1 144 ? 27.627  3.523   12.467  1.00 21.19 ? 143 GLU   A CA   1 
ATOM   2179  C  C    . GLU   A 1 144 ? 26.372  3.714   11.613  1.00 23.39 ? 143 GLU   A C    1 
ATOM   2180  O  O    . GLU   A 1 144 ? 25.309  3.170   11.899  1.00 25.22 ? 143 GLU   A O    1 
ATOM   2181  C  CB   . GLU   A 1 144 ? 27.607  2.178   13.266  1.00 32.96 ? 143 GLU   A CB   1 
ATOM   2182  C  CG   . GLU   A 1 144 ? 29.003  1.658   13.592  1.00 41.62 ? 143 GLU   A CG   1 
ATOM   2183  C  CD   . GLU   A 1 144 ? 28.979  0.385   14.423  1.00 62.19 ? 143 GLU   A CD   1 
ATOM   2184  O  OE1  . GLU   A 1 144 ? 27.941  0.118   15.089  1.00 58.02 ? 143 GLU   A OE1  1 
ATOM   2185  O  OE2  . GLU   A 1 144 ? 29.966  -0.383  14.364  1.00 68.24 ? 143 GLU   A OE2  1 
ATOM   2186  H  H    . GLU   A 1 144 ? 27.128  4.592   14.048  1.00 30.63 ? 143 GLU   A H    1 
ATOM   2187  H  HA   . GLU   A 1 144 ? 28.391  3.527   11.869  1.00 25.43 ? 143 GLU   A HA   1 
ATOM   2188  H  HB2  . GLU   A 1 144 ? 27.136  2.315   14.103  1.00 39.55 ? 143 GLU   A HB2  1 
ATOM   2189  H  HB3  . GLU   A 1 144 ? 27.153  1.504   12.737  1.00 39.55 ? 143 GLU   A HB3  1 
ATOM   2190  H  HG2  . GLU   A 1 144 ? 29.470  1.468   12.764  1.00 49.95 ? 143 GLU   A HG2  1 
ATOM   2191  H  HG3  . GLU   A 1 144 ? 29.482  2.335   14.095  1.00 49.95 ? 143 GLU   A HG3  1 
ATOM   2192  N  N    . ALA   A 1 145 ? 26.500  4.526   10.561  1.00 22.14 ? 144 ALA   A N    1 
ATOM   2193  C  CA   . ALA   A 1 145 ? 25.348  5.053   9.847   1.00 21.17 ? 144 ALA   A CA   1 
ATOM   2194  C  C    . ALA   A 1 145 ? 25.094  4.402   8.492   1.00 22.46 ? 144 ALA   A C    1 
ATOM   2195  O  O    . ALA   A 1 145 ? 24.156  4.816   7.802   1.00 20.38 ? 144 ALA   A O    1 
ATOM   2196  C  CB   . ALA   A 1 145 ? 25.516  6.570   9.635   1.00 22.86 ? 144 ALA   A CB   1 
ATOM   2197  H  H    . ALA   A 1 145 ? 27.255  4.785   10.242  1.00 26.57 ? 144 ALA   A H    1 
ATOM   2198  H  HA   . ALA   A 1 145 ? 24.567  4.887   10.398  1.00 25.40 ? 144 ALA   A HA   1 
ATOM   2199  H  HB1  . ALA   A 1 145 ? 24.652  7.000   9.732   1.00 27.43 ? 144 ALA   A HB1  1 
ATOM   2200  H  HB2  . ALA   A 1 145 ? 26.134  6.915   10.298  1.00 27.43 ? 144 ALA   A HB2  1 
ATOM   2201  H  HB3  . ALA   A 1 145 ? 25.865  6.727   8.744   1.00 27.43 ? 144 ALA   A HB3  1 
ATOM   2202  N  N    . ALA   A 1 146 ? 25.873  3.391   8.098   1.00 20.49 ? 145 ALA   A N    1 
ATOM   2203  C  CA   . ALA   A 1 146 ? 25.721  2.827   6.756   1.00 21.60 ? 145 ALA   A CA   1 
ATOM   2204  C  C    . ALA   A 1 146 ? 24.326  2.245   6.549   1.00 20.51 ? 145 ALA   A C    1 
ATOM   2205  O  O    . ALA   A 1 146 ? 23.713  2.429   5.491   1.00 17.70 ? 145 ALA   A O    1 
ATOM   2206  C  CB   . ALA   A 1 146 ? 26.773  1.758   6.498   1.00 21.17 ? 145 ALA   A CB   1 
ATOM   2207  H  H    . ALA   A 1 146 ? 26.484  3.022   8.578   1.00 24.58 ? 145 ALA   A H    1 
ATOM   2208  H  HA   . ALA   A 1 146 ? 25.854  3.543   6.115   1.00 25.92 ? 145 ALA   A HA   1 
ATOM   2209  H  HB1  . ALA   A 1 146 ? 26.602  1.349   5.636   1.00 25.41 ? 145 ALA   A HB1  1 
ATOM   2210  H  HB2  . ALA   A 1 146 ? 27.650  2.172   6.500   1.00 25.41 ? 145 ALA   A HB2  1 
ATOM   2211  H  HB3  . ALA   A 1 146 ? 26.721  1.089   7.198   1.00 25.41 ? 145 ALA   A HB3  1 
ATOM   2212  N  N    . ASN   A 1 147 ? 23.813  1.512   7.532   1.00 20.15 ? 146 ASN   A N    1 
ATOM   2213  C  CA   . ASN   A 1 147 ? 22.493  0.912   7.360   1.00 19.92 ? 146 ASN   A CA   1 
ATOM   2214  C  C    . ASN   A 1 147 ? 21.393  1.962   7.335   1.00 18.94 ? 146 ASN   A C    1 
ATOM   2215  O  O    . ASN   A 1 147 ? 20.455  1.867   6.530   1.00 20.78 ? 146 ASN   A O    1 
ATOM   2216  C  CB   . ASN   A 1 147 ? 22.250  -0.120  8.462   1.00 21.89 ? 146 ASN   A CB   1 
ATOM   2217  C  CG   . ASN   A 1 147 ? 22.834  -1.460  8.099   1.00 28.05 ? 146 ASN   A CG   1 
ATOM   2218  O  OD1  . ASN   A 1 147 ? 23.961  -1.778  8.462   1.00 34.46 ? 146 ASN   A OD1  1 
ATOM   2219  N  ND2  . ASN   A 1 147 ? 22.087  -2.228  7.331   1.00 29.64 ? 146 ASN   A ND2  1 
ATOM   2220  H  H    . ASN   A 1 147 ? 24.196  1.352   8.285   1.00 24.18 ? 146 ASN   A H    1 
ATOM   2221  H  HA   . ASN   A 1 147 ? 22.466  0.451   6.507   1.00 23.90 ? 146 ASN   A HA   1 
ATOM   2222  H  HB2  . ASN   A 1 147 ? 22.667  0.183   9.284   1.00 26.27 ? 146 ASN   A HB2  1 
ATOM   2223  H  HB3  . ASN   A 1 147 ? 21.295  -0.229  8.596   1.00 26.27 ? 146 ASN   A HB3  1 
ATOM   2224  H  HD21 . ASN   A 1 147 ? 21.316  -1.953  7.068   1.00 35.57 ? 146 ASN   A HD21 1 
ATOM   2225  H  HD22 . ASN   A 1 147 ? 22.371  -3.004  7.093   1.00 35.57 ? 146 ASN   A HD22 1 
ATOM   2226  N  N    . PHE   A 1 148 ? 21.486  2.967   8.201   1.00 18.36 ? 147 PHE   A N    1 
ATOM   2227  C  CA   . PHE   A 1 148 ? 20.515  4.060   8.179   1.00 18.71 ? 147 PHE   A CA   1 
ATOM   2228  C  C    . PHE   A 1 148 ? 20.501  4.749   6.813   1.00 20.26 ? 147 PHE   A C    1 
ATOM   2229  O  O    . PHE   A 1 148 ? 19.441  5.006   6.242   1.00 18.16 ? 147 PHE   A O    1 
ATOM   2230  C  CB   . PHE   A 1 148 ? 20.859  5.055   9.295   1.00 18.85 ? 147 PHE   A CB   1 
ATOM   2231  C  CG   . PHE   A 1 148 ? 19.783  6.050   9.609   1.00 21.38 ? 147 PHE   A CG   1 
ATOM   2232  C  CD1  . PHE   A 1 148 ? 18.471  5.653   9.837   1.00 22.43 ? 147 PHE   A CD1  1 
ATOM   2233  C  CD2  . PHE   A 1 148 ? 20.090  7.406   9.714   1.00 26.18 ? 147 PHE   A CD2  1 
ATOM   2234  C  CE1  . PHE   A 1 148 ? 17.468  6.578   10.142  1.00 20.30 ? 147 PHE   A CE1  1 
ATOM   2235  C  CE2  . PHE   A 1 148 ? 19.084  8.346   10.048  1.00 27.48 ? 147 PHE   A CE2  1 
ATOM   2236  C  CZ   . PHE   A 1 148 ? 17.770  7.924   10.262  1.00 22.98 ? 147 PHE   A CZ   1 
ATOM   2237  H  H    . PHE   A 1 148 ? 22.095  3.042   8.804   1.00 22.04 ? 147 PHE   A H    1 
ATOM   2238  H  HA   . PHE   A 1 148 ? 19.625  3.711   8.341   1.00 22.45 ? 147 PHE   A HA   1 
ATOM   2239  H  HB2  . PHE   A 1 148 ? 21.039  4.556   10.107  1.00 22.62 ? 147 PHE   A HB2  1 
ATOM   2240  H  HB3  . PHE   A 1 148 ? 21.648  5.553   9.029   1.00 22.62 ? 147 PHE   A HB3  1 
ATOM   2241  H  HD1  . PHE   A 1 148 ? 18.256  4.750   9.786   1.00 26.92 ? 147 PHE   A HD1  1 
ATOM   2242  H  HD2  . PHE   A 1 148 ? 20.961  7.696   9.564   1.00 31.42 ? 147 PHE   A HD2  1 
ATOM   2243  H  HE1  . PHE   A 1 148 ? 16.593  6.288   10.265  1.00 24.36 ? 147 PHE   A HE1  1 
ATOM   2244  H  HE2  . PHE   A 1 148 ? 19.300  9.247   10.124  1.00 32.98 ? 147 PHE   A HE2  1 
ATOM   2245  H  HZ   . PHE   A 1 148 ? 17.108  8.538   10.483  1.00 27.58 ? 147 PHE   A HZ   1 
ATOM   2246  N  N    . CYS   A 1 149 ? 21.673  5.050   6.272   1.00 19.47 ? 148 CYS   A N    1 
ATOM   2247  C  CA   . CYS   A 1 149 ? 21.734  5.701   4.957   1.00 17.48 ? 148 CYS   A CA   1 
ATOM   2248  C  C    . CYS   A 1 149 ? 21.154  4.820   3.856   1.00 19.95 ? 148 CYS   A C    1 
ATOM   2249  O  O    . CYS   A 1 149 ? 20.427  5.306   2.989   1.00 18.35 ? 148 CYS   A O    1 
ATOM   2250  C  CB   . CYS   A 1 149 ? 23.173  6.099   4.641   1.00 18.72 ? 148 CYS   A CB   1 
ATOM   2251  S  SG   . CYS   A 1 149 ? 23.753  7.488   5.675   1.00 21.80 ? 148 CYS   A SG   1 
ATOM   2252  H  H    . CYS   A 1 149 ? 22.438  4.894   6.632   1.00 23.36 ? 148 CYS   A H    1 
ATOM   2253  H  HA   . CYS   A 1 149 ? 21.198  6.509   4.987   1.00 20.98 ? 148 CYS   A HA   1 
ATOM   2254  H  HB2  . CYS   A 1 149 ? 23.755  5.340   4.800   1.00 22.46 ? 148 CYS   A HB2  1 
ATOM   2255  H  HB3  . CYS   A 1 149 ? 23.230  6.371   3.711   1.00 22.46 ? 148 CYS   A HB3  1 
ATOM   2256  H  HG   . CYS   A 1 149 ? 24.861  7.796   5.331   1.00 26.16 ? 148 CYS   A HG   1 
ATOM   2257  N  N    . ALA   A 1 150 ? 21.422  3.519   3.893   1.00 18.02 ? 149 ALA   A N    1 
ATOM   2258  C  CA   . ALA   A 1 150 ? 20.864  2.634   2.883   1.00 18.90 ? 149 ALA   A CA   1 
ATOM   2259  C  C    . ALA   A 1 150 ? 19.348  2.544   3.004   1.00 17.00 ? 149 ALA   A C    1 
ATOM   2260  O  O    . ALA   A 1 150 ? 18.653  2.440   1.996   1.00 19.91 ? 149 ALA   A O    1 
ATOM   2261  C  CB   . ALA   A 1 150 ? 21.505  1.250   2.991   1.00 19.09 ? 149 ALA   A CB   1 
ATOM   2262  H  H    . ALA   A 1 150 ? 21.915  3.131   4.482   1.00 21.62 ? 149 ALA   A H    1 
ATOM   2263  H  HA   . ALA   A 1 150 ? 21.070  2.989   2.003   1.00 22.68 ? 149 ALA   A HA   1 
ATOM   2264  H  HB1  . ALA   A 1 150 ? 20.957  0.610   2.511   1.00 22.90 ? 149 ALA   A HB1  1 
ATOM   2265  H  HB2  . ALA   A 1 150 ? 22.393  1.282   2.603   1.00 22.90 ? 149 ALA   A HB2  1 
ATOM   2266  H  HB3  . ALA   A 1 150 ? 21.562  1.001   3.927   1.00 22.90 ? 149 ALA   A HB3  1 
ATOM   2267  N  N    . LEU   A 1 151 ? 18.821  2.531   4.236   1.00 16.62 ? 150 LEU   A N    1 
ATOM   2268  C  CA   . LEU   A 1 151 ? 17.377  2.495   4.421   1.00 17.04 ? 150 LEU   A CA   1 
ATOM   2269  C  C    . LEU   A 1 151 ? 16.738  3.777   3.909   1.00 18.53 ? 150 LEU   A C    1 
ATOM   2270  O  O    . LEU   A 1 151 ? 15.683  3.739   3.260   1.00 20.44 ? 150 LEU   A O    1 
ATOM   2271  C  CB   . LEU   A 1 151 ? 17.057  2.295   5.904   1.00 19.88 ? 150 LEU   A CB   1 
ATOM   2272  C  CG   . LEU   A 1 151 ? 17.193  0.857   6.400   1.00 22.21 ? 150 LEU   A CG   1 
ATOM   2273  C  CD1  . LEU   A 1 151 ? 17.061  0.867   7.945   1.00 21.36 ? 150 LEU   A CD1  1 
ATOM   2274  C  CD2  . LEU   A 1 151 ? 16.172  -0.079  5.785   1.00 24.06 ? 150 LEU   A CD2  1 
ATOM   2275  H  H    . LEU   A 1 151 ? 19.275  2.543   4.966   1.00 19.94 ? 150 LEU   A H    1 
ATOM   2276  H  HA   . LEU   A 1 151 ? 17.005  1.749   3.926   1.00 20.45 ? 150 LEU   A HA   1 
ATOM   2277  H  HB2  . LEU   A 1 151 ? 17.663  2.843   6.426   1.00 23.85 ? 150 LEU   A HB2  1 
ATOM   2278  H  HB3  . LEU   A 1 151 ? 16.140  2.573   6.061   1.00 23.85 ? 150 LEU   A HB3  1 
ATOM   2279  H  HG   . LEU   A 1 151 ? 18.058  0.510   6.132   1.00 26.65 ? 150 LEU   A HG   1 
ATOM   2280  H  HD11 . LEU   A 1 151 ? 17.259  -0.020  8.285   1.00 25.63 ? 150 LEU   A HD11 1 
ATOM   2281  H  HD12 . LEU   A 1 151 ? 17.690  1.509   8.311   1.00 25.63 ? 150 LEU   A HD12 1 
ATOM   2282  H  HD13 . LEU   A 1 151 ? 16.155  1.118   8.183   1.00 25.63 ? 150 LEU   A HD13 1 
ATOM   2283  H  HD21 . LEU   A 1 151 ? 16.117  -0.884  6.324   1.00 28.87 ? 150 LEU   A HD21 1 
ATOM   2284  H  HD22 . LEU   A 1 151 ? 15.310  0.365   5.764   1.00 28.87 ? 150 LEU   A HD22 1 
ATOM   2285  H  HD23 . LEU   A 1 151 ? 16.452  -0.303  4.884   1.00 28.87 ? 150 LEU   A HD23 1 
ATOM   2286  N  N    . ILE   A 1 152 ? 17.372  4.920   4.175   1.00 21.52 ? 151 ILE   A N    1 
ATOM   2287  C  CA   . ILE   A 1 152 ? 16.827  6.184   3.682   1.00 20.20 ? 151 ILE   A CA   1 
ATOM   2288  C  C    . ILE   A 1 152 ? 16.733  6.164   2.163   1.00 22.89 ? 151 ILE   A C    1 
ATOM   2289  O  O    . ILE   A 1 152 ? 15.706  6.544   1.592   1.00 19.87 ? 151 ILE   A O    1 
ATOM   2290  C  CB   . ILE   A 1 152 ? 17.658  7.381   4.163   1.00 21.54 ? 151 ILE   A CB   1 
ATOM   2291  C  CG1  . ILE   A 1 152 ? 17.500  7.631   5.654   1.00 25.10 ? 151 ILE   A CG1  1 
ATOM   2292  C  CG2  . ILE   A 1 152 ? 17.233  8.670   3.418   1.00 20.86 ? 151 ILE   A CG2  1 
ATOM   2293  C  CD1  . ILE   A 1 152 ? 18.609  8.479   6.211   1.00 23.90 ? 151 ILE   A CD1  1 
ATOM   2294  H  H    . ILE   A 1 152 ? 18.100  4.989   4.627   1.00 25.82 ? 151 ILE   A H    1 
ATOM   2295  H  HA   . ILE   A 1 152 ? 15.934  6.280   4.048   1.00 24.24 ? 151 ILE   A HA   1 
ATOM   2296  H  HB   . ILE   A 1 152 ? 18.584  7.160   3.975   1.00 25.85 ? 151 ILE   A HB   1 
ATOM   2297  H  HG12 . ILE   A 1 152 ? 16.660  8.090   5.812   1.00 30.11 ? 151 ILE   A HG12 1 
ATOM   2298  H  HG13 . ILE   A 1 152 ? 17.506  6.781   6.121   1.00 30.11 ? 151 ILE   A HG13 1 
ATOM   2299  H  HG21 . ILE   A 1 152 ? 17.535  9.441   3.924   1.00 25.03 ? 151 ILE   A HG21 1 
ATOM   2300  H  HG22 . ILE   A 1 152 ? 17.637  8.673   2.537   1.00 25.03 ? 151 ILE   A HG22 1 
ATOM   2301  H  HG23 . ILE   A 1 152 ? 16.266  8.684   3.339   1.00 25.03 ? 151 ILE   A HG23 1 
ATOM   2302  H  HD11 . ILE   A 1 152 ? 18.273  8.981   6.970   1.00 28.68 ? 151 ILE   A HD11 1 
ATOM   2303  H  HD12 . ILE   A 1 152 ? 19.337  7.903   6.492   1.00 28.68 ? 151 ILE   A HD12 1 
ATOM   2304  H  HD13 . ILE   A 1 152 ? 18.917  9.089   5.522   1.00 28.68 ? 151 ILE   A HD13 1 
ATOM   2305  N  N    . LEU   A 1 153 ? 17.812  5.730   1.494   1.00 21.73 ? 152 LEU   A N    1 
ATOM   2306  C  CA   . LEU   A 1 153 ? 17.813  5.590   0.035   1.00 21.32 ? 152 LEU   A CA   1 
ATOM   2307  C  C    . LEU   A 1 153 ? 16.684  4.659   -0.426  1.00 22.27 ? 152 LEU   A C    1 
ATOM   2308  O  O    . LEU   A 1 153 ? 15.959  4.970   -1.376  1.00 23.20 ? 152 LEU   A O    1 
ATOM   2309  C  CB   . LEU   A 1 153 ? 19.167  5.054   -0.448  1.00 19.10 ? 152 LEU   A CB   1 
ATOM   2310  C  CG   . LEU   A 1 153 ? 20.388  5.973   -0.356  1.00 19.84 ? 152 LEU   A CG   1 
ATOM   2311  C  CD1  . LEU   A 1 153 ? 21.732  5.275   -0.302  1.00 24.78 ? 152 LEU   A CD1  1 
ATOM   2312  C  CD2  . LEU   A 1 153 ? 20.333  6.965   -1.495  1.00 23.62 ? 152 LEU   A CD2  1 
ATOM   2313  H  H    . LEU   A 1 153 ? 18.557  5.510   1.864   1.00 26.07 ? 152 LEU   A H    1 
ATOM   2314  H  HA   . LEU   A 1 153 ? 17.677  6.464   -0.361  1.00 25.59 ? 152 LEU   A HA   1 
ATOM   2315  H  HB2  . LEU   A 1 153 ? 19.374  4.265   0.077   1.00 22.92 ? 152 LEU   A HB2  1 
ATOM   2316  H  HB3  . LEU   A 1 153 ? 19.070  4.814   -1.383  1.00 22.92 ? 152 LEU   A HB3  1 
ATOM   2317  H  HG   . LEU   A 1 153 ? 20.338  6.424   0.501   1.00 23.81 ? 152 LEU   A HG   1 
ATOM   2318  H  HD11 . LEU   A 1 153 ? 22.412  5.918   -0.048  1.00 29.73 ? 152 LEU   A HD11 1 
ATOM   2319  H  HD12 . LEU   A 1 153 ? 21.691  4.561   0.353   1.00 29.73 ? 152 LEU   A HD12 1 
ATOM   2320  H  HD13 . LEU   A 1 153 ? 21.933  4.909   -1.178  1.00 29.73 ? 152 LEU   A HD13 1 
ATOM   2321  H  HD21 . LEU   A 1 153 ? 21.063  7.597   -1.400  1.00 28.35 ? 152 LEU   A HD21 1 
ATOM   2322  H  HD22 . LEU   A 1 153 ? 20.417  6.487   -2.335  1.00 28.35 ? 152 LEU   A HD22 1 
ATOM   2323  H  HD23 . LEU   A 1 153 ? 19.484  7.433   -1.465  1.00 28.35 ? 152 LEU   A HD23 1 
ATOM   2324  N  N    . ALA   A 1 154 ? 16.495  3.522   0.258   1.00 19.53 ? 153 ALA   A N    1 
ATOM   2325  C  CA   . ALA   A 1 154 ? 15.450  2.585   -0.147  1.00 21.29 ? 153 ALA   A CA   1 
ATOM   2326  C  C    . ALA   A 1 154 ? 14.047  3.144   0.107   1.00 20.27 ? 153 ALA   A C    1 
ATOM   2327  O  O    . ALA   A 1 154 ? 13.172  3.031   -0.752  1.00 24.92 ? 153 ALA   A O    1 
ATOM   2328  C  CB   . ALA   A 1 154 ? 15.633  1.233   0.547   1.00 19.62 ? 153 ALA   A CB   1 
ATOM   2329  H  H    . ALA   A 1 154 ? 16.950  3.279   0.946   1.00 23.44 ? 153 ALA   A H    1 
ATOM   2330  H  HA   . ALA   A 1 154 ? 15.539  2.441   -1.102  1.00 25.54 ? 153 ALA   A HA   1 
ATOM   2331  H  HB1  . ALA   A 1 154 ? 14.949  0.622   0.231   1.00 23.54 ? 153 ALA   A HB1  1 
ATOM   2332  H  HB2  . ALA   A 1 154 ? 16.512  0.885   0.333   1.00 23.54 ? 153 ALA   A HB2  1 
ATOM   2333  H  HB3  . ALA   A 1 154 ? 15.549  1.356   1.505   1.00 23.54 ? 153 ALA   A HB3  1 
ATOM   2334  N  N    . TYR   A 1 155 ? 13.802  3.704   1.294   1.00 19.86 ? 154 TYR   A N    1 
ATOM   2335  C  CA   . TYR   A 1 155 ? 12.488  4.281   1.579   1.00 22.45 ? 154 TYR   A CA   1 
ATOM   2336  C  C    . TYR   A 1 155 ? 12.139  5.397   0.594   1.00 25.91 ? 154 TYR   A C    1 
ATOM   2337  O  O    . TYR   A 1 155 ? 10.992  5.496   0.138   1.00 26.65 ? 154 TYR   A O    1 
ATOM   2338  C  CB   . TYR   A 1 155 ? 12.442  4.825   2.998   1.00 22.10 ? 154 TYR   A CB   1 
ATOM   2339  C  CG   . TYR   A 1 155 ? 12.173  3.783   4.062   1.00 21.72 ? 154 TYR   A CG   1 
ATOM   2340  C  CD1  . TYR   A 1 155 ? 10.922  3.197   4.172   1.00 25.93 ? 154 TYR   A CD1  1 
ATOM   2341  C  CD2  . TYR   A 1 155 ? 13.166  3.397   4.948   1.00 21.61 ? 154 TYR   A CD2  1 
ATOM   2342  C  CE1  . TYR   A 1 155 ? 10.660  2.237   5.140   1.00 23.40 ? 154 TYR   A CE1  1 
ATOM   2343  C  CE2  . TYR   A 1 155 ? 12.920  2.417   5.935   1.00 19.37 ? 154 TYR   A CE2  1 
ATOM   2344  C  CZ   . TYR   A 1 155 ? 11.655  1.861   6.027   1.00 21.96 ? 154 TYR   A CZ   1 
ATOM   2345  O  OH   . TYR   A 1 155 ? 11.374  0.895   6.979   1.00 23.04 ? 154 TYR   A OH   1 
ATOM   2346  H  H    . TYR   A 1 155 ? 14.367  3.762   1.940   1.00 23.83 ? 154 TYR   A H    1 
ATOM   2347  H  HA   . TYR   A 1 155 ? 11.828  3.575   1.496   1.00 26.94 ? 154 TYR   A HA   1 
ATOM   2348  H  HB2  . TYR   A 1 155 ? 13.298  5.235   3.199   1.00 26.52 ? 154 TYR   A HB2  1 
ATOM   2349  H  HB3  . TYR   A 1 155 ? 11.737  5.488   3.052   1.00 26.52 ? 154 TYR   A HB3  1 
ATOM   2350  H  HD1  . TYR   A 1 155 ? 10.245  3.452   3.587   1.00 31.12 ? 154 TYR   A HD1  1 
ATOM   2351  H  HD2  . TYR   A 1 155 ? 14.007  3.789   4.891   1.00 25.94 ? 154 TYR   A HD2  1 
ATOM   2352  H  HE1  . TYR   A 1 155 ? 9.817   1.847   5.193   1.00 28.08 ? 154 TYR   A HE1  1 
ATOM   2353  H  HE2  . TYR   A 1 155 ? 13.597  2.150   6.513   1.00 23.24 ? 154 TYR   A HE2  1 
ATOM   2354  H  HH   . TYR   A 1 155 ? 10.609  1.024   7.302   1.00 27.65 ? 154 TYR   A HH   1 
ATOM   2355  N  N    . CYS   A 1 156 ? 13.112  6.241   0.255   1.00 21.00 ? 155 CYS   A N    1 
ATOM   2356  C  CA   . CYS   A 1 156 ? 12.887  7.383   -0.635  1.00 18.98 ? 155 CYS   A CA   1 
ATOM   2357  C  C    . CYS   A 1 156 ? 13.024  7.042   -2.107  1.00 22.44 ? 155 CYS   A C    1 
ATOM   2358  O  O    . CYS   A 1 156 ? 12.898  7.938   -2.955  1.00 23.32 ? 155 CYS   A O    1 
ATOM   2359  C  CB   . CYS   A 1 156 ? 13.856  8.513   -0.302  1.00 22.73 ? 155 CYS   A CB   1 
ATOM   2360  S  SG   . CYS   A 1 156 ? 13.629  9.220   1.337   1.00 24.52 ? 155 CYS   A SG   1 
ATOM   2361  H  H    . CYS   A 1 156 ? 13.924  6.175   0.532   1.00 25.20 ? 155 CYS   A H    1 
ATOM   2362  H  HA   . CYS   A 1 156 ? 11.982  7.697   -0.484  1.00 22.78 ? 155 CYS   A HA   1 
ATOM   2363  H  HB2  . CYS   A 1 156 ? 14.762  8.169   -0.352  1.00 27.27 ? 155 CYS   A HB2  1 
ATOM   2364  H  HB3  . CYS   A 1 156 ? 13.736  9.225   -0.950  1.00 27.27 ? 155 CYS   A HB3  1 
ATOM   2365  H  HG   . CYS   A 1 156 ? 14.245  8.567   2.133   1.00 29.43 ? 155 CYS   A HG   1 
ATOM   2366  N  N    . ASN   A 1 157 ? 13.279  5.785   -2.437  1.00 23.64 ? 156 ASN   A N    1 
ATOM   2367  C  CA   . ASN   A 1 157 ? 13.419  5.355   -3.825  1.00 25.30 ? 156 ASN   A CA   1 
ATOM   2368  C  C    . ASN   A 1 157 ? 14.457  6.187   -4.565  1.00 28.26 ? 156 ASN   A C    1 
ATOM   2369  O  O    . ASN   A 1 157 ? 14.239  6.642   -5.692  1.00 23.64 ? 156 ASN   A O    1 
ATOM   2370  C  CB   . ASN   A 1 157 ? 12.069  5.423   -4.535  1.00 29.92 ? 156 ASN   A CB   1 
ATOM   2371  C  CG   . ASN   A 1 157 ? 11.330  4.132   -4.471  1.00 33.94 ? 156 ASN   A CG   1 
ATOM   2372  O  OD1  . ASN   A 1 157 ? 11.664  3.175   -5.185  1.00 33.40 ? 156 ASN   A OD1  1 
ATOM   2373  N  ND2  . ASN   A 1 157 ? 10.309  4.077   -3.601  1.00 35.41 ? 156 ASN   A ND2  1 
ATOM   2374  H  H    . ASN   A 1 157 ? 13.378  5.149   -1.867  1.00 28.37 ? 156 ASN   A H    1 
ATOM   2375  H  HA   . ASN   A 1 157 ? 13.732  4.436   -3.830  1.00 30.35 ? 156 ASN   A HA   1 
ATOM   2376  H  HB2  . ASN   A 1 157 ? 11.523  6.105   -4.113  1.00 35.90 ? 156 ASN   A HB2  1 
ATOM   2377  H  HB3  . ASN   A 1 157 ? 12.212  5.644   -5.468  1.00 35.90 ? 156 ASN   A HB3  1 
ATOM   2378  H  HD21 . ASN   A 1 157 ? 10.116  4.763   -3.120  1.00 42.50 ? 156 ASN   A HD21 1 
ATOM   2379  H  HD22 . ASN   A 1 157 ? 9.848   3.355   -3.524  1.00 42.50 ? 156 ASN   A HD22 1 
ATOM   2380  N  N    . LYS   A 1 158 ? 15.617  6.357   -3.941  1.00 23.33 ? 157 LYS   A N    1 
ATOM   2381  C  CA   . LYS   A 1 158 ? 16.742  7.046   -4.542  1.00 22.41 ? 157 LYS   A CA   1 
ATOM   2382  C  C    . LYS   A 1 158 ? 17.851  6.038   -4.795  1.00 24.79 ? 157 LYS   A C    1 
ATOM   2383  O  O    . LYS   A 1 158 ? 18.110  5.179   -3.950  1.00 27.60 ? 157 LYS   A O    1 
ATOM   2384  C  CB   . LYS   A 1 158 ? 17.262  8.156   -3.619  1.00 25.05 ? 157 LYS   A CB   1 
ATOM   2385  C  CG   . LYS   A 1 158 ? 16.258  9.269   -3.391  1.00 28.84 ? 157 LYS   A CG   1 
ATOM   2386  C  CD   . LYS   A 1 158 ? 15.834  9.937   -4.690  1.00 29.29 ? 157 LYS   A CD   1 
ATOM   2387  C  CE   . LYS   A 1 158 ? 15.213  11.280  -4.415  1.00 34.36 ? 157 LYS   A CE   1 
ATOM   2388  N  NZ   . LYS   A 1 158 ? 14.196  11.708  -5.396  1.00 40.40 ? 157 LYS   A NZ   1 
ATOM   2389  H  H    . LYS   A 1 158 ? 15.777  6.072   -3.145  1.00 28.00 ? 157 LYS   A H    1 
ATOM   2390  H  HA   . LYS   A 1 158 ? 16.477  7.451   -5.383  1.00 26.89 ? 157 LYS   A HA   1 
ATOM   2391  H  HB2  . LYS   A 1 158 ? 17.478  7.770   -2.756  1.00 30.06 ? 157 LYS   A HB2  1 
ATOM   2392  H  HB3  . LYS   A 1 158 ? 18.055  8.548   -4.016  1.00 30.06 ? 157 LYS   A HB3  1 
ATOM   2393  H  HG2  . LYS   A 1 158 ? 15.466  8.901   -2.968  1.00 34.61 ? 157 LYS   A HG2  1 
ATOM   2394  H  HG3  . LYS   A 1 158 ? 16.656  9.945   -2.820  1.00 34.61 ? 157 LYS   A HG3  1 
ATOM   2395  H  HD2  . LYS   A 1 158 ? 16.609  10.066  -5.258  1.00 35.15 ? 157 LYS   A HD2  1 
ATOM   2396  H  HD3  . LYS   A 1 158 ? 15.180  9.382   -5.143  1.00 35.15 ? 157 LYS   A HD3  1 
ATOM   2397  H  HE2  . LYS   A 1 158 ? 14.783  11.249  -3.546  1.00 41.23 ? 157 LYS   A HE2  1 
ATOM   2398  H  HE3  . LYS   A 1 158 ? 15.915  11.949  -4.413  1.00 41.23 ? 157 LYS   A HE3  1 
ATOM   2399  H  HZ1  . LYS   A 1 158 ? 13.855  12.494  -5.158  1.00 48.48 ? 157 LYS   A HZ1  1 
ATOM   2400  H  HZ2  . LYS   A 1 158 ? 14.565  11.785  -6.202  1.00 48.48 ? 157 LYS   A HZ2  1 
ATOM   2401  H  HZ3  . LYS   A 1 158 ? 13.540  11.108  -5.435  1.00 48.48 ? 157 LYS   A HZ3  1 
ATOM   2402  N  N    . THR   A 1 159 ? 18.521  6.166   -5.931  1.00 25.58 ? 158 THR   A N    1 
ATOM   2403  C  CA   . THR   A 1 159 ? 19.663  5.308   -6.212  1.00 28.24 ? 158 THR   A CA   1 
ATOM   2404  C  C    . THR   A 1 159 ? 20.934  6.001   -5.752  1.00 24.14 ? 158 THR   A C    1 
ATOM   2405  O  O    . THR   A 1 159 ? 21.023  7.235   -5.718  1.00 21.44 ? 158 THR   A O    1 
ATOM   2406  C  CB   . THR   A 1 159 ? 19.776  4.969   -7.705  1.00 32.95 ? 158 THR   A CB   1 
ATOM   2407  O  OG1  . THR   A 1 159 ? 20.522  5.968   -8.403  1.00 41.71 ? 158 THR   A OG1  1 
ATOM   2408  C  CG2  . THR   A 1 159 ? 18.416  4.880   -8.326  1.00 33.86 ? 158 THR   A CG2  1 
ATOM   2409  H  H    . THR   A 1 159 ? 18.335  6.735   -6.549  1.00 30.69 ? 158 THR   A H    1 
ATOM   2410  H  HA   . THR   A 1 159 ? 19.554  4.469   -5.737  1.00 33.89 ? 158 THR   A HA   1 
ATOM   2411  H  HB   . THR   A 1 159 ? 20.230  4.115   -7.788  1.00 39.55 ? 158 THR   A HB   1 
ATOM   2412  H  HG1  . THR   A 1 159 ? 20.076  6.678   -8.451  1.00 50.05 ? 158 THR   A HG1  1 
ATOM   2413  H  HG21 . THR   A 1 159 ? 18.441  4.291   -9.097  1.00 40.63 ? 158 THR   A HG21 1 
ATOM   2414  H  HG22 . THR   A 1 159 ? 17.780  4.530   -7.683  1.00 40.63 ? 158 THR   A HG22 1 
ATOM   2415  H  HG23 . THR   A 1 159 ? 18.124  5.760   -8.611  1.00 40.63 ? 158 THR   A HG23 1 
ATOM   2416  N  N    . VAL   A 1 160 ? 21.927  5.185   -5.396  1.00 25.81 ? 159 VAL   A N    1 
ATOM   2417  C  CA   . VAL   A 1 160 ? 23.230  5.722   -5.039  1.00 21.95 ? 159 VAL   A CA   1 
ATOM   2418  C  C    . VAL   A 1 160 ? 23.771  6.471   -6.239  1.00 21.28 ? 159 VAL   A C    1 
ATOM   2419  O  O    . VAL   A 1 160 ? 23.778  5.953   -7.364  1.00 26.27 ? 159 VAL   A O    1 
ATOM   2420  C  CB   . VAL   A 1 160 ? 24.167  4.590   -4.587  1.00 25.60 ? 159 VAL   A CB   1 
ATOM   2421  C  CG1  . VAL   A 1 160 ? 25.576  5.117   -4.419  1.00 22.34 ? 159 VAL   A CG1  1 
ATOM   2422  C  CG2  . VAL   A 1 160 ? 23.647  3.974   -3.292  1.00 26.99 ? 159 VAL   A CG2  1 
ATOM   2423  H  H    . VAL   A 1 160 ? 21.869  4.328   -5.354  1.00 30.97 ? 159 VAL   A H    1 
ATOM   2424  H  HA   . VAL   A 1 160 ? 23.148  6.339   -4.295  1.00 26.34 ? 159 VAL   A HA   1 
ATOM   2425  H  HB   . VAL   A 1 160 ? 24.190  3.894   -5.262  1.00 30.73 ? 159 VAL   A HB   1 
ATOM   2426  H  HG11 . VAL   A 1 160 ? 26.073  4.511   -3.846  1.00 26.81 ? 159 VAL   A HG11 1 
ATOM   2427  H  HG12 . VAL   A 1 160 ? 26.000  5.170   -5.290  1.00 26.81 ? 159 VAL   A HG12 1 
ATOM   2428  H  HG13 . VAL   A 1 160 ? 25.538  5.998   -4.015  1.00 26.81 ? 159 VAL   A HG13 1 
ATOM   2429  H  HG21 . VAL   A 1 160 ? 24.038  3.093   -3.183  1.00 32.39 ? 159 VAL   A HG21 1 
ATOM   2430  H  HG22 . VAL   A 1 160 ? 23.900  4.543   -2.549  1.00 32.39 ? 159 VAL   A HG22 1 
ATOM   2431  H  HG23 . VAL   A 1 160 ? 22.681  3.904   -3.341  1.00 32.39 ? 159 VAL   A HG23 1 
ATOM   2432  N  N    . GLY   A 1 161 ? 24.228  7.691   -6.011  1.00 19.69 ? 160 GLY   A N    1 
ATOM   2433  C  CA   . GLY   A 1 161 ? 24.750  8.553   -7.049  1.00 17.80 ? 160 GLY   A CA   1 
ATOM   2434  C  C    . GLY   A 1 161 ? 23.792  9.626   -7.506  1.00 18.43 ? 160 GLY   A C    1 
ATOM   2435  O  O    . GLY   A 1 161 ? 24.207  10.573  -8.201  1.00 20.78 ? 160 GLY   A O    1 
ATOM   2436  H  H    . GLY   A 1 161 ? 24.245  8.054   -5.231  1.00 23.62 ? 160 GLY   A H    1 
ATOM   2437  H  HA2  . GLY   A 1 161 ? 25.551  8.989   -6.720  1.00 21.36 ? 160 GLY   A HA2  1 
ATOM   2438  H  HA3  . GLY   A 1 161 ? 24.979  8.010   -7.820  1.00 21.36 ? 160 GLY   A HA3  1 
ATOM   2439  N  N    . GLU   A 1 162 ? 22.532  9.494   -7.162  1.00 16.97 ? 161 GLU   A N    1 
ATOM   2440  C  CA   . GLU   A 1 162 ? 21.513  10.471  -7.518  1.00 17.26 ? 161 GLU   A CA   1 
ATOM   2441  C  C    . GLU   A 1 162 ? 21.385  11.537  -6.441  1.00 20.94 ? 161 GLU   A C    1 
ATOM   2442  O  O    . GLU   A 1 162 ? 21.180  11.215  -5.267  1.00 18.75 ? 161 GLU   A O    1 
ATOM   2443  C  CB   . GLU   A 1 162 ? 20.188  9.747   -7.712  1.00 23.65 ? 161 GLU   A CB   1 
ATOM   2444  C  CG   . GLU   A 1 162 ? 19.011  10.628  -7.975  1.00 28.10 ? 161 GLU   A CG   1 
ATOM   2445  C  CD   . GLU   A 1 162 ? 17.756  9.810   -8.186  1.00 27.25 ? 161 GLU   A CD   1 
ATOM   2446  O  OE1  . GLU   A 1 162 ? 17.741  8.571   -7.838  1.00 28.49 ? 161 GLU   A OE1  1 
ATOM   2447  O  OE2  . GLU   A 1 162 ? 16.767  10.449  -8.579  1.00 32.13 ? 161 GLU   A OE2  1 
ATOM   2448  H  H    . GLU   A 1 162 ? 22.226  8.830   -6.709  1.00 20.36 ? 161 GLU   A H    1 
ATOM   2449  H  HA   . GLU   A 1 162 ? 21.762  10.926  -8.338  1.00 20.71 ? 161 GLU   A HA   1 
ATOM   2450  H  HB2  . GLU   A 1 162 ? 20.275  9.147   -8.469  1.00 28.38 ? 161 GLU   A HB2  1 
ATOM   2451  H  HB3  . GLU   A 1 162 ? 19.996  9.241   -6.908  1.00 28.38 ? 161 GLU   A HB3  1 
ATOM   2452  H  HG2  . GLU   A 1 162 ? 18.872  11.215  -7.216  1.00 33.72 ? 161 GLU   A HG2  1 
ATOM   2453  H  HG3  . GLU   A 1 162 ? 19.174  11.152  -8.775  1.00 33.72 ? 161 GLU   A HG3  1 
ATOM   2454  N  N    . LEU   A 1 163 ? 21.492  12.802  -6.833  1.00 18.96 ? 162 LEU   A N    1 
ATOM   2455  C  CA   . LEU   A 1 163 ? 21.291  13.876  -5.864  1.00 18.53 ? 162 LEU   A CA   1 
ATOM   2456  C  C    . LEU   A 1 163 ? 19.804  13.992  -5.502  1.00 16.97 ? 162 LEU   A C    1 
ATOM   2457  O  O    . LEU   A 1 163 ? 18.928  14.088  -6.369  1.00 19.36 ? 162 LEU   A O    1 
ATOM   2458  C  CB   . LEU   A 1 163 ? 21.807  15.208  -6.418  1.00 20.55 ? 162 LEU   A CB   1 
ATOM   2459  C  CG   . LEU   A 1 163 ? 21.669  16.372  -5.418  1.00 19.88 ? 162 LEU   A CG   1 
ATOM   2460  C  CD1  . LEU   A 1 163 ? 22.498  16.207  -4.129  1.00 20.15 ? 162 LEU   A CD1  1 
ATOM   2461  C  CD2  . LEU   A 1 163 ? 21.965  17.717  -6.097  1.00 22.93 ? 162 LEU   A CD2  1 
ATOM   2462  H  H    . LEU   A 1 163 ? 21.675  13.060  -7.633  1.00 22.75 ? 162 LEU   A H    1 
ATOM   2463  H  HA   . LEU   A 1 163 ? 21.791  13.673  -5.057  1.00 22.24 ? 162 LEU   A HA   1 
ATOM   2464  H  HB2  . LEU   A 1 163 ? 22.747  15.113  -6.639  1.00 24.66 ? 162 LEU   A HB2  1 
ATOM   2465  H  HB3  . LEU   A 1 163 ? 21.300  15.434  -7.214  1.00 24.66 ? 162 LEU   A HB3  1 
ATOM   2466  H  HG   . LEU   A 1 163 ? 20.745  16.365  -5.124  1.00 23.86 ? 162 LEU   A HG   1 
ATOM   2467  H  HD11 . LEU   A 1 163 ? 21.979  15.703  -3.483  1.00 24.18 ? 162 LEU   A HD11 1 
ATOM   2468  H  HD12 . LEU   A 1 163 ? 23.317  15.732  -4.339  1.00 24.18 ? 162 LEU   A HD12 1 
ATOM   2469  H  HD13 . LEU   A 1 163 ? 22.707  17.085  -3.773  1.00 24.18 ? 162 LEU   A HD13 1 
ATOM   2470  H  HD21 . LEU   A 1 163 ? 22.139  18.384  -5.414  1.00 27.52 ? 162 LEU   A HD21 1 
ATOM   2471  H  HD22 . LEU   A 1 163 ? 22.742  17.619  -6.669  1.00 27.52 ? 162 LEU   A HD22 1 
ATOM   2472  H  HD23 . LEU   A 1 163 ? 21.196  17.980  -6.626  1.00 27.52 ? 162 LEU   A HD23 1 
ATOM   2473  N  N    . GLY   A 1 164 ? 19.494  13.968  -4.206  1.00 15.42 ? 163 GLY   A N    1 
ATOM   2474  C  CA   . GLY   A 1 164 ? 18.141  14.154  -3.733  1.00 18.25 ? 163 GLY   A CA   1 
ATOM   2475  C  C    . GLY   A 1 164 ? 17.973  15.491  -3.009  1.00 16.87 ? 163 GLY   A C    1 
ATOM   2476  O  O    . GLY   A 1 164 ? 18.922  16.242  -2.821  1.00 15.00 ? 163 GLY   A O    1 
ATOM   2477  H  H    . GLY   A 1 164 ? 20.067  13.843  -3.577  1.00 18.50 ? 163 GLY   A H    1 
ATOM   2478  H  HA2  . GLY   A 1 164 ? 17.529  14.131  -4.485  1.00 21.91 ? 163 GLY   A HA2  1 
ATOM   2479  H  HA3  . GLY   A 1 164 ? 17.913  13.439  -3.118  1.00 21.91 ? 163 GLY   A HA3  1 
ATOM   2480  N  N    . ASP   A 1 165 ? 16.716  15.792  -2.678  1.00 14.97 ? 164 ASP   A N    1 
ATOM   2481  C  CA   . ASP   A 1 165 ? 16.297  17.043  -2.072  1.00 13.11 ? 164 ASP   A CA   1 
ATOM   2482  C  C    . ASP   A 1 165 ? 16.114  16.812  -0.561  1.00 15.53 ? 164 ASP   A C    1 
ATOM   2483  O  O    . ASP   A 1 165 ? 15.431  15.859  -0.160  1.00 18.44 ? 164 ASP   A O    1 
ATOM   2484  C  CB   . ASP   A 1 165 ? 14.999  17.529  -2.738  1.00 17.47 ? 164 ASP   A CB   1 
ATOM   2485  C  CG   . ASP   A 1 165 ? 14.407  18.792  -2.108  1.00 21.69 ? 164 ASP   A CG   1 
ATOM   2486  O  OD1  . ASP   A 1 165 ? 14.100  18.770  -0.889  1.00 20.28 ? 164 ASP   A OD1  1 
ATOM   2487  O  OD2  . ASP   A 1 165 ? 14.205  19.806  -2.857  1.00 17.88 ? 164 ASP   A OD2  1 
ATOM   2488  H  H    . ASP   A 1 165 ? 16.057  15.254  -2.804  1.00 17.97 ? 164 ASP   A H    1 
ATOM   2489  H  HA   . ASP   A 1 165 ? 16.964  17.738  -2.186  1.00 15.73 ? 164 ASP   A HA   1 
ATOM   2490  H  HB2  . ASP   A 1 165 ? 15.182  17.724  -3.670  1.00 20.96 ? 164 ASP   A HB2  1 
ATOM   2491  H  HB3  . ASP   A 1 165 ? 14.333  16.827  -2.670  1.00 20.96 ? 164 ASP   A HB3  1 
ATOM   2492  N  N    . VAL   A 1 166 ? 16.739  17.664  0.254   1.00 15.42 ? 165 VAL   A N    1 
ATOM   2493  C  CA   . VAL   A 1 166 ? 16.713  17.452  1.716   1.00 14.09 ? 165 VAL   A CA   1 
ATOM   2494  C  C    . VAL   A 1 166 ? 15.294  17.561  2.250   1.00 18.03 ? 165 VAL   A C    1 
ATOM   2495  O  O    . VAL   A 1 166 ? 14.858  16.733  3.059   1.00 16.31 ? 165 VAL   A O    1 
ATOM   2496  C  CB   . VAL   A 1 166 ? 17.668  18.424  2.431   1.00 13.87 ? 165 VAL   A CB   1 
ATOM   2497  C  CG1  . VAL   A 1 166 ? 17.403  18.432  3.953   1.00 18.03 ? 165 VAL   A CG1  1 
ATOM   2498  C  CG2  . VAL   A 1 166 ? 19.140  18.047  2.178   1.00 16.27 ? 165 VAL   A CG2  1 
ATOM   2499  H  H    . VAL   A 1 166 ? 17.177  18.359  -0.001  1.00 18.50 ? 165 VAL   A H    1 
ATOM   2500  H  HA   . VAL   A 1 166 ? 17.026  16.551  1.893   1.00 16.91 ? 165 VAL   A HA   1 
ATOM   2501  H  HB   . VAL   A 1 166 ? 17.507  19.312  2.074   1.00 16.65 ? 165 VAL   A HB   1 
ATOM   2502  H  HG11 . VAL   A 1 166 ? 18.183  18.786  4.408   1.00 21.63 ? 165 VAL   A HG11 1 
ATOM   2503  H  HG12 . VAL   A 1 166 ? 16.631  18.990  4.136   1.00 21.63 ? 165 VAL   A HG12 1 
ATOM   2504  H  HG13 . VAL   A 1 166 ? 17.232  17.524  4.248   1.00 21.63 ? 165 VAL   A HG13 1 
ATOM   2505  H  HG21 . VAL   A 1 166 ? 19.690  18.841  2.269   1.00 19.52 ? 165 VAL   A HG21 1 
ATOM   2506  H  HG22 . VAL   A 1 166 ? 19.412  17.381  2.829   1.00 19.52 ? 165 VAL   A HG22 1 
ATOM   2507  H  HG23 . VAL   A 1 166 ? 19.224  17.687  1.281   1.00 19.52 ? 165 VAL   A HG23 1 
ATOM   2508  N  N    . ARG   A 1 167 ? 14.568  18.613  1.851   1.00 17.48 ? 166 ARG   A N    1 
ATOM   2509  C  CA   . ARG   A 1 167 ? 13.176  18.774  2.273   1.00 19.61 ? 166 ARG   A CA   1 
ATOM   2510  C  C    . ARG   A 1 167 ? 12.332  17.556  1.893   1.00 17.33 ? 166 ARG   A C    1 
ATOM   2511  O  O    . ARG   A 1 167 ? 11.559  17.044  2.722   1.00 19.04 ? 166 ARG   A O    1 
ATOM   2512  C  CB   . ARG   A 1 167 ? 12.597  20.063  1.671   1.00 16.09 ? 166 ARG   A CB   1 
ATOM   2513  C  CG   . ARG   A 1 167 ? 11.139  20.352  2.041   1.00 19.72 ? 166 ARG   A CG   1 
ATOM   2514  C  CD   . ARG   A 1 167 ? 10.589  21.565  1.320   1.00 18.17 ? 166 ARG   A CD   1 
ATOM   2515  N  NE   . ARG   A 1 167 ? 10.443  21.258  -0.110  1.00 19.12 ? 166 ARG   A NE   1 
ATOM   2516  C  CZ   . ARG   A 1 167 ? 9.278   21.082  -0.715  1.00 33.96 ? 166 ARG   A CZ   1 
ATOM   2517  N  NH1  . ARG   A 1 167 ? 8.130   21.249  -0.069  1.00 31.72 ? 166 ARG   A NH1  1 
ATOM   2518  N  NH2  . ARG   A 1 167 ? 9.261   20.719  -1.999  1.00 32.01 ? 166 ARG   A NH2  1 
ATOM   2519  H  H    . ARG   A 1 167 ? 14.857  19.242  1.340   1.00 20.97 ? 166 ARG   A H    1 
ATOM   2520  H  HA   . ARG   A 1 167 ? 13.145  18.856  3.239   1.00 23.53 ? 166 ARG   A HA   1 
ATOM   2521  H  HB2  . ARG   A 1 167 ? 13.130  20.812  1.980   1.00 19.30 ? 166 ARG   A HB2  1 
ATOM   2522  H  HB3  . ARG   A 1 167 ? 12.645  19.998  0.705   1.00 19.30 ? 166 ARG   A HB3  1 
ATOM   2523  H  HG2  . ARG   A 1 167 ? 10.593  19.587  1.803   1.00 23.67 ? 166 ARG   A HG2  1 
ATOM   2524  H  HG3  . ARG   A 1 167 ? 11.080  20.518  2.995   1.00 23.67 ? 166 ARG   A HG3  1 
ATOM   2525  H  HD2  . ARG   A 1 167 ? 9.720   21.796  1.682   1.00 21.81 ? 166 ARG   A HD2  1 
ATOM   2526  H  HD3  . ARG   A 1 167 ? 11.200  22.312  1.420   1.00 21.81 ? 166 ARG   A HD3  1 
ATOM   2527  H  HE   . ARG   A 1 167 ? 11.158  21.188  -0.583  1.00 22.94 ? 166 ARG   A HE   1 
ATOM   2528  H  HH11 . ARG   A 1 167 ? 8.133   21.476  0.761   1.00 38.06 ? 166 ARG   A HH11 1 
ATOM   2529  H  HH12 . ARG   A 1 167 ? 7.384   21.130  -0.480  1.00 38.06 ? 166 ARG   A HH12 1 
ATOM   2530  H  HH21 . ARG   A 1 167 ? 10.000  20.603  -2.422  1.00 38.42 ? 166 ARG   A HH21 1 
ATOM   2531  H  HH22 . ARG   A 1 167 ? 8.511   20.602  -2.403  1.00 38.42 ? 166 ARG   A HH22 1 
ATOM   2532  N  N    . GLU   A 1 168 ? 12.482  17.062  0.658   1.00 16.21 ? 167 GLU   A N    1 
ATOM   2533  C  CA   . GLU   A 1 168 ? 11.724  15.883  0.225   1.00 17.73 ? 167 GLU   A CA   1 
ATOM   2534  C  C    . GLU   A 1 168 ? 12.098  14.653  1.043   1.00 17.40 ? 167 GLU   A C    1 
ATOM   2535  O  O    . GLU   A 1 168 ? 11.227  13.837  1.391   1.00 18.92 ? 167 GLU   A O    1 
ATOM   2536  C  CB   . GLU   A 1 168 ? 11.956  15.609  -1.273  1.00 18.61 ? 167 GLU   A CB   1 
ATOM   2537  C  CG   . GLU   A 1 168 ? 11.402  16.741  -2.155  1.00 23.40 ? 167 GLU   A CG   1 
ATOM   2538  C  CD   . GLU   A 1 168 ? 11.514  16.433  -3.640  1.00 23.16 ? 167 GLU   A CD   1 
ATOM   2539  O  OE1  . GLU   A 1 168 ? 12.033  15.365  -3.957  1.00 22.92 ? 167 GLU   A OE1  1 
ATOM   2540  O  OE2  . GLU   A 1 168 ? 11.068  17.256  -4.456  1.00 27.39 ? 167 GLU   A OE2  1 
ATOM   2541  H  H    . GLU   A 1 168 ? 13.008  17.385  0.061   1.00 19.46 ? 167 GLU   A H    1 
ATOM   2542  H  HA   . GLU   A 1 168 ? 10.780  16.065  0.355   1.00 21.27 ? 167 GLU   A HA   1 
ATOM   2543  H  HB2  . GLU   A 1 168 ? 12.909  15.533  -1.439  1.00 22.34 ? 167 GLU   A HB2  1 
ATOM   2544  H  HB3  . GLU   A 1 168 ? 11.510  14.785  -1.520  1.00 22.34 ? 167 GLU   A HB3  1 
ATOM   2545  H  HG2  . GLU   A 1 168 ? 10.465  16.875  -1.946  1.00 28.08 ? 167 GLU   A HG2  1 
ATOM   2546  H  HG3  . GLU   A 1 168 ? 11.902  17.553  -1.979  1.00 28.08 ? 167 GLU   A HG3  1 
ATOM   2547  N  N    . THR   A 1 169 ? 13.383  14.508  1.355   1.00 17.51 ? 168 THR   A N    1 
ATOM   2548  C  CA   . THR   A 1 169 ? 13.863  13.360  2.111   1.00 15.53 ? 168 THR   A CA   1 
ATOM   2549  C  C    . THR   A 1 169 ? 13.314  13.401  3.532   1.00 17.93 ? 168 THR   A C    1 
ATOM   2550  O  O    . THR   A 1 169 ? 12.752  12.408  4.029   1.00 18.89 ? 168 THR   A O    1 
ATOM   2551  C  CB   . THR   A 1 169 ? 15.400  13.337  2.115   1.00 16.38 ? 168 THR   A CB   1 
ATOM   2552  O  OG1  . THR   A 1 169 ? 15.876  13.292  0.747   1.00 19.73 ? 168 THR   A OG1  1 
ATOM   2553  C  CG2  . THR   A 1 169 ? 15.930  12.137  2.876   1.00 19.63 ? 168 THR   A CG2  1 
ATOM   2554  H  H    . THR   A 1 169 ? 14.002  15.065  1.139   1.00 21.01 ? 168 THR   A H    1 
ATOM   2555  H  HA   . THR   A 1 169 ? 13.560  12.541  1.687   1.00 18.63 ? 168 THR   A HA   1 
ATOM   2556  H  HB   . THR   A 1 169 ? 15.733  14.135  2.556   1.00 19.66 ? 168 THR   A HB   1 
ATOM   2557  H  HG1  . THR   A 1 169 ? 16.272  14.008  0.557   1.00 23.68 ? 168 THR   A HG1  1 
ATOM   2558  H  HG21 . THR   A 1 169 ? 16.795  11.876  2.523   1.00 23.56 ? 168 THR   A HG21 1 
ATOM   2559  H  HG22 . THR   A 1 169 ? 16.027  12.357  3.816   1.00 23.56 ? 168 THR   A HG22 1 
ATOM   2560  H  HG23 . THR   A 1 169 ? 15.317  11.391  2.789   1.00 23.56 ? 168 THR   A HG23 1 
ATOM   2561  N  N    . MET   A 1 170 ? 13.418  14.562  4.169   1.00 17.22 ? 169 MET   A N    1 
ATOM   2562  C  CA   . MET   A 1 170 ? 12.924  14.700  5.540   1.00 17.96 ? 169 MET   A CA   1 
ATOM   2563  C  C    . MET   A 1 170 ? 11.423  14.445  5.583   1.00 19.27 ? 169 MET   A C    1 
ATOM   2564  O  O    . MET   A 1 170 ? 10.912  13.766  6.491   1.00 21.54 ? 169 MET   A O    1 
ATOM   2565  C  CB   . MET   A 1 170 ? 13.230  16.106  6.081   1.00 17.16 ? 169 MET   A CB   1 
ATOM   2566  C  CG   . MET   A 1 170 ? 14.730  16.445  6.191   1.00 22.15 ? 169 MET   A CG   1 
ATOM   2567  S  SD   . MET   A 1 170 ? 15.643  15.365  7.330   1.00 22.14 ? 169 MET   A SD   1 
ATOM   2568  C  CE   . MET   A 1 170 ? 15.103  16.005  8.924   1.00 19.63 ? 169 MET   A CE   1 
ATOM   2569  H  H    . MET   A 1 170 ? 13.765  15.276  3.838   1.00 20.66 ? 169 MET   A H    1 
ATOM   2570  H  HA   . MET   A 1 170 ? 13.386  14.061  6.104   1.00 21.55 ? 169 MET   A HA   1 
ATOM   2571  H  HB2  . MET   A 1 170 ? 12.826  16.759  5.487   1.00 20.59 ? 169 MET   A HB2  1 
ATOM   2572  H  HB3  . MET   A 1 170 ? 12.847  16.184  6.969   1.00 20.59 ? 169 MET   A HB3  1 
ATOM   2573  H  HG2  . MET   A 1 170 ? 15.135  16.359  5.314   1.00 26.58 ? 169 MET   A HG2  1 
ATOM   2574  H  HG3  . MET   A 1 170 ? 14.821  17.356  6.511   1.00 26.58 ? 169 MET   A HG3  1 
ATOM   2575  H  HE1  . MET   A 1 170 ? 15.836  15.938  9.556   1.00 23.56 ? 169 MET   A HE1  1 
ATOM   2576  H  HE2  . MET   A 1 170 ? 14.841  16.933  8.819   1.00 23.56 ? 169 MET   A HE2  1 
ATOM   2577  H  HE3  . MET   A 1 170 ? 14.349  15.481  9.235   1.00 23.56 ? 169 MET   A HE3  1 
ATOM   2578  N  N    . SER   A 1 171 ? 10.706  14.981  4.596   1.00 19.02 ? 170 SER   A N    1 
ATOM   2579  C  CA   . SER   A 1 171 ? 9.260   14.833  4.534   1.00 22.00 ? 170 SER   A CA   1 
ATOM   2580  C  C    . SER   A 1 171 ? 8.857   13.370  4.487   1.00 23.53 ? 170 SER   A C    1 
ATOM   2581  O  O    . SER   A 1 171 ? 7.970   12.934  5.230   1.00 24.04 ? 170 SER   A O    1 
ATOM   2582  C  CB   . SER   A 1 171 ? 8.707   15.571  3.320   1.00 22.45 ? 170 SER   A CB   1 
ATOM   2583  O  OG   . SER   A 1 171 ? 7.303   15.435  3.256   1.00 32.49 ? 170 SER   A OG   1 
ATOM   2584  H  H    . SER   A 1 171 ? 11.038  15.437  3.947   1.00 22.82 ? 170 SER   A H    1 
ATOM   2585  H  HA   . SER   A 1 171 ? 8.878   15.229  5.333   1.00 26.40 ? 170 SER   A HA   1 
ATOM   2586  H  HB2  . SER   A 1 171 ? 8.932   16.512  3.391   1.00 26.94 ? 170 SER   A HB2  1 
ATOM   2587  H  HB3  . SER   A 1 171 ? 9.099   15.197  2.515   1.00 26.94 ? 170 SER   A HB3  1 
ATOM   2588  H  HG   . SER   A 1 171 ? 7.101   14.760  2.799   1.00 38.99 ? 170 SER   A HG   1 
ATOM   2589  N  N    . TYR   A 1 172 ? 9.526   12.583  3.647   1.00 20.78 ? 171 TYR   A N    1 
ATOM   2590  C  CA   . TYR   A 1 172 ? 9.160   11.181  3.565   1.00 23.09 ? 171 TYR   A CA   1 
ATOM   2591  C  C    . TYR   A 1 172 ? 9.494   10.445  4.862   1.00 20.80 ? 171 TYR   A C    1 
ATOM   2592  O  O    . TYR   A 1 172 ? 8.695   9.643   5.342   1.00 25.60 ? 171 TYR   A O    1 
ATOM   2593  C  CB   . TYR   A 1 172 ? 9.813   10.523  2.335   1.00 23.10 ? 171 TYR   A CB   1 
ATOM   2594  C  CG   . TYR   A 1 172 ? 9.100   9.215   2.060   1.00 29.44 ? 171 TYR   A CG   1 
ATOM   2595  C  CD1  . TYR   A 1 172 ? 7.811   9.208   1.530   1.00 34.79 ? 171 TYR   A CD1  1 
ATOM   2596  C  CD2  . TYR   A 1 172 ? 9.680   7.994   2.387   1.00 30.84 ? 171 TYR   A CD2  1 
ATOM   2597  C  CE1  . TYR   A 1 172 ? 7.131   8.026   1.317   1.00 41.70 ? 171 TYR   A CE1  1 
ATOM   2598  C  CE2  . TYR   A 1 172 ? 8.994   6.789   2.185   1.00 29.81 ? 171 TYR   A CE2  1 
ATOM   2599  C  CZ   . TYR   A 1 172 ? 7.728   6.817   1.641   1.00 39.16 ? 171 TYR   A CZ   1 
ATOM   2600  O  OH   . TYR   A 1 172 ? 7.041   5.645   1.422   1.00 50.51 ? 171 TYR   A OH   1 
ATOM   2601  H  H    . TYR   A 1 172 ? 10.170  12.830  3.134   1.00 24.93 ? 171 TYR   A H    1 
ATOM   2602  H  HA   . TYR   A 1 172 ? 8.201   11.110  3.438   1.00 27.70 ? 171 TYR   A HA   1 
ATOM   2603  H  HB2  . TYR   A 1 172 ? 9.725   11.102  1.562   1.00 27.72 ? 171 TYR   A HB2  1 
ATOM   2604  H  HB3  . TYR   A 1 172 ? 10.750  10.344  2.512   1.00 27.72 ? 171 TYR   A HB3  1 
ATOM   2605  H  HD1  . TYR   A 1 172 ? 7.402   10.015  1.315   1.00 41.75 ? 171 TYR   A HD1  1 
ATOM   2606  H  HD2  . TYR   A 1 172 ? 10.538  7.977   2.746   1.00 37.01 ? 171 TYR   A HD2  1 
ATOM   2607  H  HE1  . TYR   A 1 172 ? 6.274   8.040   0.958   1.00 50.04 ? 171 TYR   A HE1  1 
ATOM   2608  H  HE2  . TYR   A 1 172 ? 9.388   5.979   2.415   1.00 35.77 ? 171 TYR   A HE2  1 
ATOM   2609  H  HH   . TYR   A 1 172 ? 7.376   5.025   1.880   1.00 60.61 ? 171 TYR   A HH   1 
ATOM   2610  N  N    . LEU   A 1 173 ? 10.650  10.724  5.467   1.00 21.55 ? 172 LEU   A N    1 
ATOM   2611  C  CA   . LEU   A 1 173 ? 10.980  10.115  6.749   1.00 19.37 ? 172 LEU   A CA   1 
ATOM   2612  C  C    . LEU   A 1 173 ? 9.974   10.525  7.813   1.00 22.49 ? 172 LEU   A C    1 
ATOM   2613  O  O    . LEU   A 1 173 ? 9.626   9.728   8.703   1.00 23.06 ? 172 LEU   A O    1 
ATOM   2614  C  CB   . LEU   A 1 173 ? 12.383  10.520  7.163   1.00 18.56 ? 172 LEU   A CB   1 
ATOM   2615  C  CG   . LEU   A 1 173 ? 13.489  10.037  6.218   1.00 20.78 ? 172 LEU   A CG   1 
ATOM   2616  C  CD1  . LEU   A 1 173 ? 14.844  10.549  6.673   1.00 21.25 ? 172 LEU   A CD1  1 
ATOM   2617  C  CD2  . LEU   A 1 173 ? 13.482  8.495   6.011   1.00 26.15 ? 172 LEU   A CD2  1 
ATOM   2618  H  H    . LEU   A 1 173 ? 11.251  11.256  5.158   1.00 25.86 ? 172 LEU   A H    1 
ATOM   2619  H  HA   . LEU   A 1 173 ? 10.957  9.149   6.660   1.00 23.24 ? 172 LEU   A HA   1 
ATOM   2620  H  HB2  . LEU   A 1 173 ? 12.428  11.489  7.196   1.00 22.27 ? 172 LEU   A HB2  1 
ATOM   2621  H  HB3  . LEU   A 1 173 ? 12.565  10.150  8.041   1.00 22.27 ? 172 LEU   A HB3  1 
ATOM   2622  H  HG   . LEU   A 1 173 ? 13.312  10.409  5.340   1.00 24.93 ? 172 LEU   A HG   1 
ATOM   2623  H  HD11 . LEU   A 1 173 ? 15.531  10.177  6.099   1.00 25.50 ? 172 LEU   A HD11 1 
ATOM   2624  H  HD12 . LEU   A 1 173 ? 14.851  11.517  6.615   1.00 25.50 ? 172 LEU   A HD12 1 
ATOM   2625  H  HD13 . LEU   A 1 173 ? 14.994  10.271  7.591   1.00 25.50 ? 172 LEU   A HD13 1 
ATOM   2626  H  HD21 . LEU   A 1 173 ? 14.364  8.211   5.724   1.00 31.38 ? 172 LEU   A HD21 1 
ATOM   2627  H  HD22 . LEU   A 1 173 ? 13.252  8.065   6.849   1.00 31.38 ? 172 LEU   A HD22 1 
ATOM   2628  H  HD23 . LEU   A 1 173 ? 12.825  8.271   5.333   1.00 31.38 ? 172 LEU   A HD23 1 
ATOM   2629  N  N    . PHE   A 1 174 ? 9.504   11.773  7.758   1.00 19.76 ? 173 PHE   A N    1 
ATOM   2630  C  CA   . PHE   A 1 174 ? 8.513   12.216  8.743   1.00 20.93 ? 173 PHE   A CA   1 
ATOM   2631  C  C    . PHE   A 1 174 ? 7.228   11.402  8.640   1.00 20.22 ? 173 PHE   A C    1 
ATOM   2632  O  O    . PHE   A 1 174 ? 6.540   11.173  9.649   1.00 20.79 ? 173 PHE   A O    1 
ATOM   2633  C  CB   . PHE   A 1 174 ? 8.200   13.703  8.556   1.00 18.28 ? 173 PHE   A CB   1 
ATOM   2634  C  CG   . PHE   A 1 174 ? 9.320   14.644  8.956   1.00 20.89 ? 173 PHE   A CG   1 
ATOM   2635  C  CD1  . PHE   A 1 174 ? 10.396  14.210  9.695   1.00 21.19 ? 173 PHE   A CD1  1 
ATOM   2636  C  CD2  . PHE   A 1 174 ? 9.278   15.986  8.582   1.00 22.36 ? 173 PHE   A CD2  1 
ATOM   2637  C  CE1  . PHE   A 1 174 ? 11.416  15.072  10.054  1.00 21.62 ? 173 PHE   A CE1  1 
ATOM   2638  C  CE2  . PHE   A 1 174 ? 10.292  16.863  8.972   1.00 21.58 ? 173 PHE   A CE2  1 
ATOM   2639  C  CZ   . PHE   A 1 174 ? 11.356  16.395  9.712   1.00 23.14 ? 173 PHE   A CZ   1 
ATOM   2640  H  H    . PHE   A 1 174 ? 9.735   12.366  7.179   1.00 23.71 ? 173 PHE   A H    1 
ATOM   2641  H  HA   . PHE   A 1 174 ? 8.886   12.097  9.630   1.00 25.11 ? 173 PHE   A HA   1 
ATOM   2642  H  HB2  . PHE   A 1 174 ? 8.008   13.862  7.618   1.00 21.93 ? 173 PHE   A HB2  1 
ATOM   2643  H  HB3  . PHE   A 1 174 ? 7.426   13.925  9.096   1.00 21.93 ? 173 PHE   A HB3  1 
ATOM   2644  H  HD1  . PHE   A 1 174 ? 10.439  13.318  9.957   1.00 25.43 ? 173 PHE   A HD1  1 
ATOM   2645  H  HD2  . PHE   A 1 174 ? 8.568   16.300  8.070   1.00 26.84 ? 173 PHE   A HD2  1 
ATOM   2646  H  HE1  . PHE   A 1 174 ? 12.146  14.751  10.532  1.00 25.95 ? 173 PHE   A HE1  1 
ATOM   2647  H  HE2  . PHE   A 1 174 ? 10.249  17.760  8.732   1.00 25.90 ? 173 PHE   A HE2  1 
ATOM   2648  H  HZ   . PHE   A 1 174 ? 12.032  16.977  9.978   1.00 27.76 ? 173 PHE   A HZ   1 
ATOM   2649  N  N    . GLN   A 1 175 ? 6.919   10.909  7.448   1.00 19.36 ? 174 GLN   A N    1 
ATOM   2650  C  CA   . GLN   A 1 175 ? 5.756   10.051  7.263   1.00 24.16 ? 174 GLN   A CA   1 
ATOM   2651  C  C    . GLN   A 1 175 ? 5.907   8.729   7.983   1.00 27.61 ? 174 GLN   A C    1 
ATOM   2652  O  O    . GLN   A 1 175 ? 4.901   8.062   8.234   1.00 28.51 ? 174 GLN   A O    1 
ATOM   2653  C  CB   . GLN   A 1 175 ? 5.503   9.815   5.789   1.00 30.72 ? 174 GLN   A CB   1 
ATOM   2654  C  CG   . GLN   A 1 175 ? 5.360   11.105  5.056   1.00 34.57 ? 174 GLN   A CG   1 
ATOM   2655  C  CD   . GLN   A 1 175 ? 4.022   11.219  4.424   1.00 51.49 ? 174 GLN   A CD   1 
ATOM   2656  O  OE1  . GLN   A 1 175 ? 3.016   11.385  5.124   1.00 52.77 ? 174 GLN   A OE1  1 
ATOM   2657  N  NE2  . GLN   A 1 175 ? 3.984   11.163  3.095   1.00 46.02 ? 174 GLN   A NE2  1 
ATOM   2658  H  H    . GLN   A 1 175 ? 7.366   11.056  6.729   1.00 23.23 ? 174 GLN   A H    1 
ATOM   2659  H  HA   . GLN   A 1 175 ? 4.976   10.501  7.623   1.00 28.99 ? 174 GLN   A HA   1 
ATOM   2660  H  HB2  . GLN   A 1 175 ? 6.249   9.327   5.408   1.00 36.86 ? 174 GLN   A HB2  1 
ATOM   2661  H  HB3  . GLN   A 1 175 ? 4.684   9.307   5.680   1.00 36.86 ? 174 GLN   A HB3  1 
ATOM   2662  H  HG2  . GLN   A 1 175 ? 5.469   11.842  5.678   1.00 41.49 ? 174 GLN   A HG2  1 
ATOM   2663  H  HG3  . GLN   A 1 175 ? 6.033   11.156  4.360   1.00 41.49 ? 174 GLN   A HG3  1 
ATOM   2664  H  HE21 . GLN   A 1 175 ? 4.712   11.064  2.647   1.00 55.22 ? 174 GLN   A HE21 1 
ATOM   2665  H  HE22 . GLN   A 1 175 ? 3.232   11.224  2.683   1.00 55.22 ? 174 GLN   A HE22 1 
ATOM   2666  N  N    . HIS   A 1 176 ? 7.134   8.354   8.343   1.00 23.22 ? 175 HIS   A N    1 
ATOM   2667  C  CA   . HIS   A 1 176 ? 7.405   7.154   9.118   1.00 22.89 ? 175 HIS   A CA   1 
ATOM   2668  C  C    . HIS   A 1 176 ? 7.732   7.471   10.572  1.00 24.35 ? 175 HIS   A C    1 
ATOM   2669  O  O    . HIS   A 1 176 ? 8.286   6.618   11.273  1.00 27.45 ? 175 HIS   A O    1 
ATOM   2670  C  CB   . HIS   A 1 176 ? 8.542   6.367   8.463   1.00 21.42 ? 175 HIS   A CB   1 
ATOM   2671  C  CG   . HIS   A 1 176 ? 8.115   5.604   7.249   1.00 27.31 ? 175 HIS   A CG   1 
ATOM   2672  N  ND1  . HIS   A 1 176 ? 7.437   4.406   7.330   1.00 31.69 ? 175 HIS   A ND1  1 
ATOM   2673  C  CD2  . HIS   A 1 176 ? 8.225   5.884   5.928   1.00 32.77 ? 175 HIS   A CD2  1 
ATOM   2674  C  CE1  . HIS   A 1 176 ? 7.189   3.956   6.112   1.00 35.89 ? 175 HIS   A CE1  1 
ATOM   2675  N  NE2  . HIS   A 1 176 ? 7.658   4.833   5.244   1.00 30.46 ? 175 HIS   A NE2  1 
ATOM   2676  H  H    . HIS   A 1 176 ? 7.845   8.795   8.143   1.00 27.87 ? 175 HIS   A H    1 
ATOM   2677  H  HA   . HIS   A 1 176 ? 6.615   6.590   9.117   1.00 27.47 ? 175 HIS   A HA   1 
ATOM   2678  H  HB2  . HIS   A 1 176 ? 9.238   6.987   8.196   1.00 25.71 ? 175 HIS   A HB2  1 
ATOM   2679  H  HB3  . HIS   A 1 176 ? 8.893   5.730   9.106   1.00 25.71 ? 175 HIS   A HB3  1 
ATOM   2680  H  HD2  . HIS   A 1 176 ? 8.611   6.643   5.554   1.00 39.32 ? 175 HIS   A HD2  1 
ATOM   2681  H  HE1  . HIS   A 1 176 ? 6.758   3.159   5.903   1.00 43.07 ? 175 HIS   A HE1  1 
ATOM   2682  H  HE2  . HIS   A 1 176 ? 7.615   4.759   4.388   1.00 36.55 ? 175 HIS   A HE2  1 
ATOM   2683  N  N    . ALA   A 1 177 ? 7.419   8.679   11.040  1.00 21.10 ? 176 ALA   A N    1 
ATOM   2684  C  CA   . ALA   A 1 177 ? 7.699   9.046   12.416  1.00 18.65 ? 176 ALA   A CA   1 
ATOM   2685  C  C    . ALA   A 1 177 ? 6.387   9.263   13.164  1.00 22.49 ? 176 ALA   A C    1 
ATOM   2686  O  O    . ALA   A 1 177 ? 5.330   9.480   12.565  1.00 22.00 ? 176 ALA   A O    1 
ATOM   2687  C  CB   . ALA   A 1 177 ? 8.559   10.302  12.506  1.00 24.87 ? 176 ALA   A CB   1 
ATOM   2688  H  H    . ALA   A 1 177 ? 7.044   9.299   10.575  1.00 25.32 ? 176 ALA   A H    1 
ATOM   2689  H  HA   . ALA   A 1 177 ? 8.191   8.326   12.841  1.00 22.38 ? 176 ALA   A HA   1 
ATOM   2690  H  HB1  . ALA   A 1 177 ? 8.965   10.344  13.386  1.00 29.84 ? 176 ALA   A HB1  1 
ATOM   2691  H  HB2  . ALA   A 1 177 ? 9.249   10.261  11.826  1.00 29.84 ? 176 ALA   A HB2  1 
ATOM   2692  H  HB3  . ALA   A 1 177 ? 7.998   11.080  12.363  1.00 29.84 ? 176 ALA   A HB3  1 
ATOM   2693  N  N    . ASN   A 1 178 ? 6.472   9.177   14.482  1.00 24.85 ? 177 ASN   A N    1 
ATOM   2694  C  CA   . ASN   A 1 178 ? 5.307   9.403   15.335  1.00 24.49 ? 177 ASN   A CA   1 
ATOM   2695  C  C    . ASN   A 1 178 ? 5.209   10.897  15.617  1.00 19.49 ? 177 ASN   A C    1 
ATOM   2696  O  O    . ASN   A 1 178 ? 5.863   11.424  16.513  1.00 22.51 ? 177 ASN   A O    1 
ATOM   2697  C  CB   . ASN   A 1 178 ? 5.391   8.610   16.626  1.00 26.28 ? 177 ASN   A CB   1 
ATOM   2698  C  CG   . ASN   A 1 178 ? 4.155   8.789   17.471  1.00 33.49 ? 177 ASN   A CG   1 
ATOM   2699  O  OD1  . ASN   A 1 178 ? 3.255   9.553   17.110  1.00 30.17 ? 177 ASN   A OD1  1 
ATOM   2700  N  ND2  . ASN   A 1 178 ? 4.094   8.091   18.598  1.00 34.89 ? 177 ASN   A ND2  1 
ATOM   2701  H  H    . ASN   A 1 178 ? 7.194   8.990   14.911  1.00 29.82 ? 177 ASN   A H    1 
ATOM   2702  H  HA   . ASN   A 1 178 ? 4.516   9.113   14.853  1.00 29.39 ? 177 ASN   A HA   1 
ATOM   2703  H  HB2  . ASN   A 1 178 ? 5.483   7.667   16.418  1.00 31.53 ? 177 ASN   A HB2  1 
ATOM   2704  H  HB3  . ASN   A 1 178 ? 6.157   8.913   17.139  1.00 31.53 ? 177 ASN   A HB3  1 
ATOM   2705  H  HD21 . ASN   A 1 178 ? 4.740   7.567   18.815  1.00 41.86 ? 177 ASN   A HD21 1 
ATOM   2706  H  HD22 . ASN   A 1 178 ? 3.407   8.161   19.111  1.00 41.86 ? 177 ASN   A HD22 1 
ATOM   2707  N  N    . LEU   A 1 179 ? 4.436   11.596  14.782  1.00 21.40 ? 178 LEU   A N    1 
ATOM   2708  C  CA   . LEU   A 1 179 ? 4.192   13.028  14.922  1.00 23.83 ? 178 LEU   A CA   1 
ATOM   2709  C  C    . LEU   A 1 179 ? 2.731   13.300  15.275  1.00 29.60 ? 178 LEU   A C    1 
ATOM   2710  O  O    . LEU   A 1 179 ? 2.231   14.403  15.041  1.00 24.52 ? 178 LEU   A O    1 
ATOM   2711  C  CB   . LEU   A 1 179 ? 4.594   13.742  13.634  1.00 22.78 ? 178 LEU   A CB   1 
ATOM   2712  C  CG   . LEU   A 1 179 ? 6.105   13.670  13.372  1.00 22.28 ? 178 LEU   A CG   1 
ATOM   2713  C  CD1  . LEU   A 1 179 ? 6.402   14.277  11.995  1.00 26.42 ? 178 LEU   A CD1  1 
ATOM   2714  C  CD2  . LEU   A 1 179 ? 6.930   14.378  14.395  1.00 22.94 ? 178 LEU   A CD2  1 
ATOM   2715  H  H    . LEU   A 1 179 ? 4.031   11.249  14.108  1.00 25.68 ? 178 LEU   A H    1 
ATOM   2716  H  HA   . LEU   A 1 179 ? 4.739   13.392  15.636  1.00 28.59 ? 178 LEU   A HA   1 
ATOM   2717  H  HB2  . LEU   A 1 179 ? 4.138   13.326  12.886  1.00 27.33 ? 178 LEU   A HB2  1 
ATOM   2718  H  HB3  . LEU   A 1 179 ? 4.343   14.676  13.699  1.00 27.33 ? 178 LEU   A HB3  1 
ATOM   2719  H  HG   . LEU   A 1 179 ? 6.358   12.734  13.413  1.00 26.74 ? 178 LEU   A HG   1 
ATOM   2720  H  HD11 . LEU   A 1 179 ? 7.087   14.957  12.091  1.00 31.70 ? 178 LEU   A HD11 1 
ATOM   2721  H  HD12 . LEU   A 1 179 ? 6.714   13.576  11.402  1.00 31.70 ? 178 LEU   A HD12 1 
ATOM   2722  H  HD13 . LEU   A 1 179 ? 5.590   14.673  11.642  1.00 31.70 ? 178 LEU   A HD13 1 
ATOM   2723  H  HD21 . LEU   A 1 179 ? 7.830   14.493  14.051  1.00 27.52 ? 178 LEU   A HD21 1 
ATOM   2724  H  HD22 . LEU   A 1 179 ? 6.532   15.245  14.576  1.00 27.52 ? 178 LEU   A HD22 1 
ATOM   2725  H  HD23 . LEU   A 1 179 ? 6.951   13.848  15.207  1.00 27.52 ? 178 LEU   A HD23 1 
ATOM   2726  N  N    . ASP   A 1 180 ? 2.040   12.302  15.843  1.00 30.37 ? 179 ASP   A N    1 
ATOM   2727  C  CA   . ASP   A 1 180 ? 0.584   12.375  15.975  1.00 36.59 ? 179 ASP   A CA   1 
ATOM   2728  C  C    . ASP   A 1 180 ? 0.143   13.544  16.856  1.00 30.61 ? 179 ASP   A C    1 
ATOM   2729  O  O    . ASP   A 1 180 ? -0.912  14.141  16.618  1.00 42.63 ? 179 ASP   A O    1 
ATOM   2730  C  CB   . ASP   A 1 180 ? 0.027   11.073  16.566  1.00 41.26 ? 179 ASP   A CB   1 
ATOM   2731  C  CG   . ASP   A 1 180 ? 0.208   9.868   15.653  1.00 42.87 ? 179 ASP   A CG   1 
ATOM   2732  O  OD1  . ASP   A 1 180 ? 0.432   10.036  14.430  1.00 48.31 ? 179 ASP   A OD1  1 
ATOM   2733  O  OD2  . ASP   A 1 180 ? 0.108   8.739   16.181  1.00 50.32 ? 179 ASP   A OD2  1 
ATOM   2734  H  H    . ASP   A 1 180 ? 2.389   11.581  16.155  1.00 36.44 ? 179 ASP   A H    1 
ATOM   2735  H  HA   . ASP   A 1 180 ? 0.222   12.500  15.084  1.00 43.91 ? 179 ASP   A HA   1 
ATOM   2736  H  HB2  . ASP   A 1 180 ? 0.486   10.886  17.400  1.00 49.51 ? 179 ASP   A HB2  1 
ATOM   2737  H  HB3  . ASP   A 1 180 ? -0.923  11.183  16.728  1.00 49.51 ? 179 ASP   A HB3  1 
ATOM   2738  N  N    . SER   A 1 181 ? 0.913   13.858  17.888  1.00 27.07 ? 180 SER   A N    1 
ATOM   2739  C  CA   . SER   A 1 181 ? 0.626   14.958  18.801  1.00 36.84 ? 180 SER   A CA   1 
ATOM   2740  C  C    . SER   A 1 181 ? 1.028   16.349  18.282  1.00 38.21 ? 180 SER   A C    1 
ATOM   2741  O  O    . SER   A 1 181 ? 0.753   17.342  18.966  1.00 36.56 ? 180 SER   A O    1 
ATOM   2742  C  CB   . SER   A 1 181 ? 1.311   14.667  20.140  1.00 39.24 ? 180 SER   A CB   1 
ATOM   2743  O  OG   . SER   A 1 181 ? 2.651   15.129  20.170  1.00 52.01 ? 180 SER   A OG   1 
ATOM   2744  H  H    . SER   A 1 181 ? 1.634   13.435  18.090  1.00 32.48 ? 180 SER   A H    1 
ATOM   2745  H  HA   . SER   A 1 181 ? -0.333  15.006  18.938  1.00 44.21 ? 180 SER   A HA   1 
ATOM   2746  H  HB2  . SER   A 1 181 ? 0.814   15.110  20.846  1.00 47.08 ? 180 SER   A HB2  1 
ATOM   2747  H  HB3  . SER   A 1 181 ? 1.310   13.708  20.287  1.00 47.08 ? 180 SER   A HB3  1 
ATOM   2748  H  HG   . SER   A 1 181 ? 3.175   14.505  19.965  1.00 62.41 ? 180 SER   A HG   1 
ATOM   2749  N  N    . CYS   A 1 182 ? 1.709   16.462  17.144  1.00 24.07 ? 181 CYS   A N    1 
ATOM   2750  C  CA   . CYS   A 1 182 ? 2.063   17.776  16.623  1.00 21.69 ? 181 CYS   A CA   1 
ATOM   2751  C  C    . CYS   A 1 182 ? 0.841   18.503  16.127  1.00 21.96 ? 181 CYS   A C    1 
ATOM   2752  O  O    . CYS   A 1 182 ? 0.029   17.911  15.467  1.00 26.17 ? 181 CYS   A O    1 
ATOM   2753  C  CB   . CYS   A 1 182 ? 3.071   17.651  15.493  1.00 21.57 ? 181 CYS   A CB   1 
ATOM   2754  S  SG   . CYS   A 1 182 ? 4.639   17.028  16.062  1.00 23.53 ? 181 CYS   A SG   1 
ATOM   2755  H  H    . CYS   A 1 182 ? 1.973   15.801  16.662  1.00 28.88 ? 181 CYS   A H    1 
ATOM   2756  H  HA   . CYS   A 1 182 ? 2.465   18.296  17.336  1.00 26.03 ? 181 CYS   A HA   1 
ATOM   2757  H  HB2  . CYS   A 1 182 ? 2.725   17.038  14.825  1.00 25.89 ? 181 CYS   A HB2  1 
ATOM   2758  H  HB3  . CYS   A 1 182 ? 3.216   18.524  15.098  1.00 25.89 ? 181 CYS   A HB3  1 
ATOM   2759  H  HG   . CYS   A 1 182 ? 5.238   16.568  15.129  1.00 28.23 ? 181 CYS   A HG   1 
ATOM   2760  N  N    . LYS   A 1 183 ? 0.719   19.781  16.402  1.00 20.57 ? 182 LYS   A N    1 
ATOM   2761  C  CA   . LYS   A 1 183 ? -0.477  20.542  16.058  1.00 21.78 ? 182 LYS   A CA   1 
ATOM   2762  C  C    . LYS   A 1 183 ? -0.049  21.935  15.650  1.00 17.72 ? 182 LYS   A C    1 
ATOM   2763  O  O    . LYS   A 1 183 ? 0.801   22.537  16.312  1.00 18.87 ? 182 LYS   A O    1 
ATOM   2764  C  CB   . LYS   A 1 183 ? -1.435  20.657  17.276  1.00 24.09 ? 182 LYS   A CB   1 
ATOM   2765  C  CG   . LYS   A 1 183 ? -2.736  21.330  16.919  1.00 31.98 ? 182 LYS   A CG   1 
ATOM   2766  C  CD   . LYS   A 1 183 ? -3.824  21.180  17.975  1.00 35.12 ? 182 LYS   A CD   1 
ATOM   2767  C  CE   . LYS   A 1 183 ? -3.624  22.124  19.099  1.00 44.33 ? 182 LYS   A CE   1 
ATOM   2768  N  NZ   . LYS   A 1 183 ? -4.957  22.416  19.704  1.00 54.01 ? 182 LYS   A NZ   1 
ATOM   2769  H  H    . LYS   A 1 183 ? 1.324   20.248  16.797  1.00 24.69 ? 182 LYS   A H    1 
ATOM   2770  H  HA   . LYS   A 1 183 ? -0.944  20.112  15.324  1.00 26.14 ? 182 LYS   A HA   1 
ATOM   2771  H  HB2  . LYS   A 1 183 ? -1.637  19.767  17.607  1.00 28.91 ? 182 LYS   A HB2  1 
ATOM   2772  H  HB3  . LYS   A 1 183 ? -1.005  21.179  17.971  1.00 28.91 ? 182 LYS   A HB3  1 
ATOM   2773  H  HG2  . LYS   A 1 183 ? -2.572  22.279  16.798  1.00 38.38 ? 182 LYS   A HG2  1 
ATOM   2774  H  HG3  . LYS   A 1 183 ? -3.071  20.944  16.095  1.00 38.38 ? 182 LYS   A HG3  1 
ATOM   2775  H  HD2  . LYS   A 1 183 ? -4.688  21.362  17.574  1.00 42.15 ? 182 LYS   A HD2  1 
ATOM   2776  H  HD3  . LYS   A 1 183 ? -3.806  20.277  18.329  1.00 42.15 ? 182 LYS   A HD3  1 
ATOM   2777  H  HE2  . LYS   A 1 183 ? -3.049  21.725  19.771  1.00 53.20 ? 182 LYS   A HE2  1 
ATOM   2778  H  HE3  . LYS   A 1 183 ? -3.232  22.950  18.775  1.00 53.20 ? 182 LYS   A HE3  1 
ATOM   2779  H  HZ1  . LYS   A 1 183 ? -4.857  22.904  20.441  1.00 64.81 ? 182 LYS   A HZ1  1 
ATOM   2780  H  HZ2  . LYS   A 1 183 ? -5.462  22.866  19.126  1.00 64.81 ? 182 LYS   A HZ2  1 
ATOM   2781  H  HZ3  . LYS   A 1 183 ? -5.369  21.655  19.915  1.00 64.81 ? 182 LYS   A HZ3  1 
ATOM   2782  N  N    . ARG   A 1 184 ? -0.680  22.466  14.624  1.00 16.49 ? 183 ARG   A N    1 
ATOM   2783  C  CA   . ARG   A 1 184 ? -0.456  23.820  14.167  1.00 16.99 ? 183 ARG   A CA   1 
ATOM   2784  C  C    . ARG   A 1 184 ? -1.812  24.473  13.923  1.00 18.38 ? 183 ARG   A C    1 
ATOM   2785  O  O    . ARG   A 1 184 ? -2.634  23.927  13.175  1.00 19.18 ? 183 ARG   A O    1 
ATOM   2786  C  CB   . ARG   A 1 184 ? 0.350   23.821  12.871  1.00 16.63 ? 183 ARG   A CB   1 
ATOM   2787  C  CG   . ARG   A 1 184 ? 0.373   25.120  12.186  1.00 17.69 ? 183 ARG   A CG   1 
ATOM   2788  C  CD   . ARG   A 1 184 ? 1.380   25.131  11.040  1.00 15.88 ? 183 ARG   A CD   1 
ATOM   2789  N  NE   . ARG   A 1 184 ? 2.743   25.214  11.530  1.00 16.48 ? 183 ARG   A NE   1 
ATOM   2790  C  CZ   . ARG   A 1 184 ? 3.823   24.922  10.837  1.00 22.80 ? 183 ARG   A CZ   1 
ATOM   2791  N  NH1  . ARG   A 1 184 ? 3.755   24.678  9.544   1.00 22.70 ? 183 ARG   A NH1  1 
ATOM   2792  N  NH2  . ARG   A 1 184 ? 5.006   24.970  11.445  1.00 26.80 ? 183 ARG   A NH2  1 
ATOM   2793  H  H    . ARG   A 1 184 ? -1.267  22.045  14.157  1.00 19.79 ? 183 ARG   A H    1 
ATOM   2794  H  HA   . ARG   A 1 184 ? 0.027   24.326  14.839  1.00 20.38 ? 183 ARG   A HA   1 
ATOM   2795  H  HB2  . ARG   A 1 184 ? 1.267   23.577  13.074  1.00 19.96 ? 183 ARG   A HB2  1 
ATOM   2796  H  HB3  . ARG   A 1 184 ? -0.039  23.173  12.262  1.00 19.96 ? 183 ARG   A HB3  1 
ATOM   2797  H  HG2  . ARG   A 1 184 ? -0.506  25.306  11.821  1.00 21.22 ? 183 ARG   A HG2  1 
ATOM   2798  H  HG3  . ARG   A 1 184 ? 0.623   25.812  12.818  1.00 21.22 ? 183 ARG   A HG3  1 
ATOM   2799  H  HD2  . ARG   A 1 184 ? 1.290   24.313  10.526  1.00 19.06 ? 183 ARG   A HD2  1 
ATOM   2800  H  HD3  . ARG   A 1 184 ? 1.213   25.900  10.473  1.00 19.06 ? 183 ARG   A HD3  1 
ATOM   2801  H  HE   . ARG   A 1 184 ? 2.854   25.476  12.341  1.00 19.78 ? 183 ARG   A HE   1 
ATOM   2802  H  HH11 . ARG   A 1 184 ? 4.470   24.489  9.104   1.00 27.23 ? 183 ARG   A HH11 1 
ATOM   2803  H  HH12 . ARG   A 1 184 ? 2.997   24.709  9.140   1.00 27.23 ? 183 ARG   A HH12 1 
ATOM   2804  H  HH21 . ARG   A 1 184 ? 5.054   25.188  12.275  1.00 32.16 ? 183 ARG   A HH21 1 
ATOM   2805  H  HH22 . ARG   A 1 184 ? 5.722   24.782  11.007  1.00 32.16 ? 183 ARG   A HH22 1 
ATOM   2806  N  N    . VAL   A 1 185 ? -2.005  25.666  14.463  1.00 16.65 ? 184 VAL   A N    1 
ATOM   2807  C  CA   . VAL   A 1 185 ? -3.211  26.452  14.203  1.00 17.49 ? 184 VAL   A CA   1 
ATOM   2808  C  C    . VAL   A 1 185 ? -2.807  27.713  13.449  1.00 16.92 ? 184 VAL   A C    1 
ATOM   2809  O  O    . VAL   A 1 185 ? -1.919  28.449  13.888  1.00 19.46 ? 184 VAL   A O    1 
ATOM   2810  C  CB   . VAL   A 1 185 ? -3.959  26.812  15.508  1.00 21.70 ? 184 VAL   A CB   1 
ATOM   2811  C  CG1  . VAL   A 1 185 ? -5.238  27.640  15.156  1.00 21.96 ? 184 VAL   A CG1  1 
ATOM   2812  C  CG2  . VAL   A 1 185 ? -4.292  25.564  16.322  1.00 20.29 ? 184 VAL   A CG2  1 
ATOM   2813  H  H    . VAL   A 1 185 ? -1.446  26.050  14.992  1.00 19.98 ? 184 VAL   A H    1 
ATOM   2814  H  HA   . VAL   A 1 185 ? -3.811  25.936  13.642  1.00 20.99 ? 184 VAL   A HA   1 
ATOM   2815  H  HB   . VAL   A 1 185 ? -3.387  27.355  16.071  1.00 26.04 ? 184 VAL   A HB   1 
ATOM   2816  H  HG11 . VAL   A 1 185 ? -5.848  27.613  15.909  1.00 26.36 ? 184 VAL   A HG11 1 
ATOM   2817  H  HG12 . VAL   A 1 185 ? -4.980  28.556  14.971  1.00 26.36 ? 184 VAL   A HG12 1 
ATOM   2818  H  HG13 . VAL   A 1 185 ? -5.661  27.251  14.374  1.00 26.36 ? 184 VAL   A HG13 1 
ATOM   2819  H  HG21 . VAL   A 1 185 ? -5.078  25.740  16.863  1.00 24.35 ? 184 VAL   A HG21 1 
ATOM   2820  H  HG22 . VAL   A 1 185 ? -4.466  24.827  15.716  1.00 24.35 ? 184 VAL   A HG22 1 
ATOM   2821  H  HG23 . VAL   A 1 185 ? -3.538  25.350  16.894  1.00 24.35 ? 184 VAL   A HG23 1 
ATOM   2822  N  N    . LEU   A 1 186 ? -3.455  27.954  12.319  1.00 18.46 ? 185 LEU   A N    1 
ATOM   2823  C  CA   . LEU   A 1 186 ? -3.203  29.108  11.477  1.00 19.19 ? 185 LEU   A CA   1 
ATOM   2824  C  C    . LEU   A 1 186 ? -4.454  29.974  11.385  1.00 25.70 ? 185 LEU   A C    1 
ATOM   2825  O  O    . LEU   A 1 186 ? -5.580  29.458  11.384  1.00 23.96 ? 185 LEU   A O    1 
ATOM   2826  C  CB   . LEU   A 1 186 ? -2.799  28.659  10.061  1.00 20.15 ? 185 LEU   A CB   1 
ATOM   2827  C  CG   . LEU   A 1 186 ? -1.548  27.798  9.908   1.00 23.37 ? 185 LEU   A CG   1 
ATOM   2828  C  CD1  . LEU   A 1 186 ? -1.425  27.250  8.516   1.00 32.80 ? 185 LEU   A CD1  1 
ATOM   2829  C  CD2  . LEU   A 1 186 ? -0.348  28.596  10.328  1.00 27.98 ? 185 LEU   A CD2  1 
ATOM   2830  H  H    . LEU   A 1 186 ? -4.070  27.440  12.007  1.00 22.15 ? 185 LEU   A H    1 
ATOM   2831  H  HA   . LEU   A 1 186 ? -2.492  29.643  11.861  1.00 23.03 ? 185 LEU   A HA   1 
ATOM   2832  H  HB2  . LEU   A 1 186 ? -3.536  28.146  9.694   1.00 24.18 ? 185 LEU   A HB2  1 
ATOM   2833  H  HB3  . LEU   A 1 186 ? -2.653  29.457  9.530   1.00 24.18 ? 185 LEU   A HB3  1 
ATOM   2834  H  HG   . LEU   A 1 186 ? -1.605  27.021  10.485  1.00 28.05 ? 185 LEU   A HG   1 
ATOM   2835  H  HD11 . LEU   A 1 186 ? -0.588  26.766  8.441   1.00 39.36 ? 185 LEU   A HD11 1 
ATOM   2836  H  HD12 . LEU   A 1 186 ? -2.170  26.652  8.346   1.00 39.36 ? 185 LEU   A HD12 1 
ATOM   2837  H  HD13 . LEU   A 1 186 ? -1.440  27.985  7.884   1.00 39.36 ? 185 LEU   A HD13 1 
ATOM   2838  H  HD21 . LEU   A 1 186 ? 0.455   28.105  10.094  1.00 33.57 ? 185 LEU   A HD21 1 
ATOM   2839  H  HD22 . LEU   A 1 186 ? -0.360  29.450  9.867   1.00 33.57 ? 185 LEU   A HD22 1 
ATOM   2840  H  HD23 . LEU   A 1 186 ? -0.382  28.737  11.287  1.00 33.57 ? 185 LEU   A HD23 1 
ATOM   2841  N  N    . ASN   A 1 187 ? -4.253  31.292  11.237  1.00 24.62 ? 186 ASN   A N    1 
ATOM   2842  C  CA   . ASN   A 1 187 ? -5.347  32.219  10.957  1.00 22.33 ? 186 ASN   A CA   1 
ATOM   2843  C  C    . ASN   A 1 187 ? -4.990  32.933  9.665   1.00 30.05 ? 186 ASN   A C    1 
ATOM   2844  O  O    . ASN   A 1 187 ? -3.837  33.336  9.476   1.00 26.47 ? 186 ASN   A O    1 
ATOM   2845  C  CB   . ASN   A 1 187 ? -5.527  33.225  12.087  1.00 28.42 ? 186 ASN   A CB   1 
ATOM   2846  C  CG   . ASN   A 1 187 ? -6.831  34.027  11.960  1.00 35.50 ? 186 ASN   A CG   1 
ATOM   2847  O  OD1  . ASN   A 1 187 ? -7.809  33.542  11.393  1.00 31.45 ? 186 ASN   A OD1  1 
ATOM   2848  N  ND2  . ASN   A 1 187 ? -6.826  35.265  12.461  1.00 36.35 ? 186 ASN   A ND2  1 
ATOM   2849  H  H    . ASN   A 1 187 ? -3.483  31.670  11.297  1.00 29.54 ? 186 ASN   A H    1 
ATOM   2850  H  HA   . ASN   A 1 187 ? -6.189  31.747  10.857  1.00 26.79 ? 186 ASN   A HA   1 
ATOM   2851  H  HB2  . ASN   A 1 187 ? -5.547  32.750  12.933  1.00 34.10 ? 186 ASN   A HB2  1 
ATOM   2852  H  HB3  . ASN   A 1 187 ? -4.786  33.850  12.075  1.00 34.10 ? 186 ASN   A HB3  1 
ATOM   2853  H  HD21 . ASN   A 1 187 ? -6.115  35.576  12.832  1.00 43.63 ? 186 ASN   A HD21 1 
ATOM   2854  H  HD22 . ASN   A 1 187 ? -7.534  35.751  12.413  1.00 43.63 ? 186 ASN   A HD22 1 
ATOM   2855  N  N    . VAL   A 1 188 ? -5.950  33.053  8.762   1.00 25.85 ? 187 VAL   A N    1 
ATOM   2856  C  CA   . VAL   A 1 188 ? -5.763  33.757  7.498   1.00 28.41 ? 187 VAL   A CA   1 
ATOM   2857  C  C    . VAL   A 1 188 ? -6.774  34.896  7.470   1.00 40.63 ? 187 VAL   A C    1 
ATOM   2858  O  O    . VAL   A 1 188 ? -7.948  34.685  7.792   1.00 35.30 ? 187 VAL   A O    1 
ATOM   2859  C  CB   . VAL   A 1 188 ? -5.942  32.811  6.302   1.00 29.87 ? 187 VAL   A CB   1 
ATOM   2860  C  CG1  . VAL   A 1 188 ? -5.895  33.593  5.003   1.00 39.02 ? 187 VAL   A CG1  1 
ATOM   2861  C  CG2  . VAL   A 1 188 ? -4.861  31.747  6.282   1.00 30.61 ? 187 VAL   A CG2  1 
ATOM   2862  H  H    . VAL   A 1 188 ? -6.739  32.726  8.858   1.00 31.02 ? 187 VAL   A H    1 
ATOM   2863  H  HA   . VAL   A 1 188 ? -4.872  34.135  7.442   1.00 34.09 ? 187 VAL   A HA   1 
ATOM   2864  H  HB   . VAL   A 1 188 ? -6.804  32.375  6.388   1.00 35.84 ? 187 VAL   A HB   1 
ATOM   2865  H  HG11 . VAL   A 1 188 ? -5.742  32.978  4.269   1.00 46.82 ? 187 VAL   A HG11 1 
ATOM   2866  H  HG12 . VAL   A 1 188 ? -6.741  34.051  4.879   1.00 46.82 ? 187 VAL   A HG12 1 
ATOM   2867  H  HG13 . VAL   A 1 188 ? -5.173  34.239  5.049   1.00 46.82 ? 187 VAL   A HG13 1 
ATOM   2868  H  HG21 . VAL   A 1 188 ? -4.710  31.467  5.366   1.00 36.73 ? 187 VAL   A HG21 1 
ATOM   2869  H  HG22 . VAL   A 1 188 ? -4.045  32.119  6.653   1.00 36.73 ? 187 VAL   A HG22 1 
ATOM   2870  H  HG23 . VAL   A 1 188 ? -5.152  30.991  6.816   1.00 36.73 ? 187 VAL   A HG23 1 
ATOM   2871  N  N    . VAL   A 1 189 ? -6.298  36.138  7.339   1.00 44.31 ? 188 VAL   A N    1 
ATOM   2872  C  CA   . VAL   A 1 189 ? -7.171  37.271  7.437   1.00 47.91 ? 188 VAL   A CA   1 
ATOM   2873  C  C    . VAL   A 1 189 ? -7.188  38.159  6.190   1.00 47.35 ? 188 VAL   A C    1 
ATOM   2874  O  O    . VAL   A 1 189 ? -6.161  38.490  5.677   1.00 43.98 ? 188 VAL   A O    1 
ATOM   2875  C  CB   . VAL   A 1 189 ? -6.807  38.110  8.654   1.00 49.56 ? 188 VAL   A CB   1 
ATOM   2876  C  CG1  . VAL   A 1 189 ? -6.617  37.272  9.874   1.00 54.14 ? 188 VAL   A CG1  1 
ATOM   2877  C  CG2  . VAL   A 1 189 ? -5.545  38.865  8.428   1.00 57.69 ? 188 VAL   A CG2  1 
ATOM   2878  H  H    . VAL   A 1 189 ? -5.496  36.406  7.171   1.00 53.17 ? 188 VAL   A H    1 
ATOM   2879  H  HA   . VAL   A 1 189 ? -8.052  36.888  7.629   1.00 57.49 ? 188 VAL   A HA   1 
ATOM   2880  H  HB   . VAL   A 1 189 ? -7.524  38.753  8.831   1.00 59.48 ? 188 VAL   A HB   1 
ATOM   2881  H  HG11 . VAL   A 1 189 ? -6.675  37.833  10.651  1.00 64.96 ? 188 VAL   A HG11 1 
ATOM   2882  H  HG12 . VAL   A 1 189 ? -7.304  36.602  9.901   1.00 64.96 ? 188 VAL   A HG12 1 
ATOM   2883  H  HG13 . VAL   A 1 189 ? -5.753  36.855  9.835   1.00 64.96 ? 188 VAL   A HG13 1 
ATOM   2884  H  HG21 . VAL   A 1 189 ? -5.757  39.790  8.284   1.00 69.23 ? 188 VAL   A HG21 1 
ATOM   2885  H  HG22 . VAL   A 1 189 ? -4.983  38.773  9.200   1.00 69.23 ? 188 VAL   A HG22 1 
ATOM   2886  H  HG23 . VAL   A 1 189 ? -5.102  38.507  7.655   1.00 69.23 ? 188 VAL   A HG23 1 
ATOM   2887  N  N    . GLY   A 1 194 ? -12.501 37.828  4.718   1.00 63.32 ? 193 GLY   A N    1 
ATOM   2888  C  CA   . GLY   A 1 194 ? -12.780 37.373  6.066   1.00 63.37 ? 193 GLY   A CA   1 
ATOM   2889  C  C    . GLY   A 1 194 ? -11.582 36.964  6.913   1.00 59.19 ? 193 GLY   A C    1 
ATOM   2890  O  O    . GLY   A 1 194 ? -10.435 37.290  6.608   1.00 59.42 ? 193 GLY   A O    1 
ATOM   2891  H  H    . GLY   A 1 194 ? -11.672 37.989  4.557   1.00 75.99 ? 193 GLY   A H    1 
ATOM   2892  H  HA2  . GLY   A 1 194 ? -13.250 38.076  6.541   1.00 76.05 ? 193 GLY   A HA2  1 
ATOM   2893  H  HA3  . GLY   A 1 194 ? -13.383 36.616  5.985   1.00 76.05 ? 193 GLY   A HA3  1 
ATOM   2894  N  N    . GLN   A 1 195 ? -11.877 36.237  7.989   1.00 58.27 ? 194 GLN   A N    1 
ATOM   2895  C  CA   . GLN   A 1 195 ? -10.891 35.748  8.948   1.00 48.27 ? 194 GLN   A CA   1 
ATOM   2896  C  C    . GLN   A 1 195 ? -11.158 34.246  9.116   1.00 51.02 ? 194 GLN   A C    1 
ATOM   2897  O  O    . GLN   A 1 195 ? -12.230 33.900  9.518   1.00 43.42 ? 194 GLN   A O    1 
ATOM   2898  C  CB   . GLN   A 1 195 ? -11.139 36.501  10.218  1.00 49.86 ? 194 GLN   A CB   1 
ATOM   2899  C  CG   . GLN   A 1 195 ? -10.265 36.176  11.364  1.00 51.59 ? 194 GLN   A CG   1 
ATOM   2900  C  CD   . GLN   A 1 195 ? -9.814  37.409  12.132  1.00 58.45 ? 194 GLN   A CD   1 
ATOM   2901  O  OE1  . GLN   A 1 195 ? -9.539  38.428  11.563  1.00 63.61 ? 194 GLN   A OE1  1 
ATOM   2902  N  NE2  . GLN   A 1 195 ? -9.589  37.242  13.417  1.00 54.94 ? 194 GLN   A NE2  1 
ATOM   2903  H  H    . GLN   A 1 195 ? -12.677 35.985  8.182   1.00 69.92 ? 194 GLN   A H    1 
ATOM   2904  H  HA   . GLN   A 1 195 ? -9.983  35.898  8.636   1.00 57.93 ? 194 GLN   A HA   1 
ATOM   2905  H  HB2  . GLN   A 1 195 ? -11.028 37.447  10.034  1.00 59.83 ? 194 GLN   A HB2  1 
ATOM   2906  H  HB3  . GLN   A 1 195 ? -12.053 36.335  10.497  1.00 59.83 ? 194 GLN   A HB3  1 
ATOM   2907  H  HG2  . GLN   A 1 195 ? -10.747 35.598  11.976  1.00 61.90 ? 194 GLN   A HG2  1 
ATOM   2908  H  HG3  . GLN   A 1 195 ? -9.484  35.719  11.022  1.00 61.90 ? 194 GLN   A HG3  1 
ATOM   2909  H  HE21 . GLN   A 1 195 ? -9.124  37.821  13.851  1.00 65.93 ? 194 GLN   A HE21 1 
ATOM   2910  H  HE22 . GLN   A 1 195 ? -9.906  36.554  13.823  1.00 65.93 ? 194 GLN   A HE22 1 
ATOM   2911  N  N    . GLN   A 1 196 ? -10.208 33.366  8.798   1.00 34.61 ? 195 GLN   A N    1 
ATOM   2912  C  CA   . GLN   A 1 196 ? -10.459 31.945  8.827   1.00 28.44 ? 195 GLN   A CA   1 
ATOM   2913  C  C    . GLN   A 1 196 ? -9.360  31.135  9.507   1.00 28.01 ? 195 GLN   A C    1 
ATOM   2914  O  O    . GLN   A 1 196 ? -8.231  31.324  9.186   1.00 27.53 ? 195 GLN   A O    1 
ATOM   2915  C  CB   . GLN   A 1 196 ? -10.597 31.478  7.398   1.00 30.05 ? 195 GLN   A CB   1 
ATOM   2916  C  CG   . GLN   A 1 196 ? -10.845 30.013  7.234   1.00 35.46 ? 195 GLN   A CG   1 
ATOM   2917  C  CD   . GLN   A 1 196 ? -10.796 29.528  5.786   1.00 50.74 ? 195 GLN   A CD   1 
ATOM   2918  O  OE1  . GLN   A 1 196 ? -9.800  28.985  5.323   1.00 50.73 ? 195 GLN   A OE1  1 
ATOM   2919  N  NE2  . GLN   A 1 196 ? -11.888 29.683  5.094   1.00 54.01 ? 195 GLN   A NE2  1 
ATOM   2920  H  H    . GLN   A 1 196 ? -9.407  33.572  8.563   1.00 41.53 ? 195 GLN   A H    1 
ATOM   2921  H  HA   . GLN   A 1 196 ? -11.325 31.808  9.264   1.00 34.13 ? 195 GLN   A HA   1 
ATOM   2922  H  HB2  . GLN   A 1 196 ? -11.340 31.948  6.989   1.00 36.06 ? 195 GLN   A HB2  1 
ATOM   2923  H  HB3  . GLN   A 1 196 ? -9.778  31.690  6.924   1.00 36.06 ? 195 GLN   A HB3  1 
ATOM   2924  H  HG2  . GLN   A 1 196 ? -10.170 29.525  7.732   1.00 42.55 ? 195 GLN   A HG2  1 
ATOM   2925  H  HG3  . GLN   A 1 196 ? -11.725 29.805  7.585   1.00 42.55 ? 195 GLN   A HG3  1 
ATOM   2926  H  HE21 . GLN   A 1 196 ? -12.590 30.012  5.466   1.00 64.81 ? 195 GLN   A HE21 1 
ATOM   2927  H  HE22 . GLN   A 1 196 ? -11.907 29.456  4.265   1.00 64.81 ? 195 GLN   A HE22 1 
ATOM   2928  N  N    . GLN   A 1 197 ? -9.713  30.238  10.417  1.00 22.80 ? 196 GLN   A N    1 
ATOM   2929  C  CA   . GLN   A 1 197 ? -8.739  29.441  11.115  1.00 23.50 ? 196 GLN   A CA   1 
ATOM   2930  C  C    . GLN   A 1 197 ? -8.753  27.966  10.667  1.00 24.67 ? 196 GLN   A C    1 
ATOM   2931  O  O    . GLN   A 1 197 ? -9.783  27.423  10.434  1.00 22.39 ? 196 GLN   A O    1 
ATOM   2932  C  CB   . GLN   A 1 197 ? -8.989  29.523  12.612  1.00 21.39 ? 196 GLN   A CB   1 
ATOM   2933  C  CG   . GLN   A 1 197 ? -8.025  28.767  13.480  1.00 26.92 ? 196 GLN   A CG   1 
ATOM   2934  C  CD   . GLN   A 1 197 ? -8.394  28.797  14.951  1.00 35.49 ? 196 GLN   A CD   1 
ATOM   2935  O  OE1  . GLN   A 1 197 ? -8.130  29.758  15.610  1.00 37.94 ? 196 GLN   A OE1  1 
ATOM   2936  N  NE2  . GLN   A 1 197 ? -8.971  27.713  15.457  1.00 34.27 ? 196 GLN   A NE2  1 
ATOM   2937  H  H    . GLN   A 1 197 ? -10.515 30.051  10.662  1.00 27.36 ? 196 GLN   A H    1 
ATOM   2938  H  HA   . GLN   A 1 197 ? -7.876  29.872  10.942  1.00 28.20 ? 196 GLN   A HA   1 
ATOM   2939  H  HB2  . GLN   A 1 197 ? -8.948  30.455  12.878  1.00 25.67 ? 196 GLN   A HB2  1 
ATOM   2940  H  HB3  . GLN   A 1 197 ? -9.876  29.175  12.793  1.00 25.67 ? 196 GLN   A HB3  1 
ATOM   2941  H  HG2  . GLN   A 1 197 ? -8.037  27.830  13.251  1.00 32.30 ? 196 GLN   A HG2  1 
ATOM   2942  H  HG3  . GLN   A 1 197 ? -7.133  29.134  13.376  1.00 32.30 ? 196 GLN   A HG3  1 
ATOM   2943  H  HE21 . GLN   A 1 197 ? -9.118  27.030  14.955  1.00 41.12 ? 196 GLN   A HE21 1 
ATOM   2944  H  HE22 . GLN   A 1 197 ? -9.198  27.695  16.286  1.00 41.12 ? 196 GLN   A HE22 1 
ATOM   2945  N  N    . THR   A 1 198 ? -7.586  27.347  10.595  1.00 19.93 ? 197 THR   A N    1 
ATOM   2946  C  CA   . THR   A 1 198 ? -7.429  25.958  10.229  1.00 23.58 ? 197 THR   A CA   1 
ATOM   2947  C  C    . THR   A 1 198 ? -6.445  25.314  11.191  1.00 19.41 ? 197 THR   A C    1 
ATOM   2948  O  O    . THR   A 1 198 ? -5.478  25.950  11.613  1.00 21.69 ? 197 THR   A O    1 
ATOM   2949  C  CB   . THR   A 1 198 ? -6.910  25.838  8.782   1.00 31.06 ? 197 THR   A CB   1 
ATOM   2950  O  OG1  . THR   A 1 198 ? -7.940  26.252  7.877   1.00 38.70 ? 197 THR   A OG1  1 
ATOM   2951  C  CG2  . THR   A 1 198 ? -6.544  24.420  8.466   1.00 39.35 ? 197 THR   A CG2  1 
ATOM   2952  H  H    . THR   A 1 198 ? -6.838  27.735  10.769  1.00 23.92 ? 197 THR   A H    1 
ATOM   2953  H  HA   . THR   A 1 198 ? -8.273  25.486  10.297  1.00 28.30 ? 197 THR   A HA   1 
ATOM   2954  H  HB   . THR   A 1 198 ? -6.123  26.395  8.677   1.00 37.27 ? 197 THR   A HB   1 
ATOM   2955  H  HG1  . THR   A 1 198 ? -7.937  27.089  7.802   1.00 46.43 ? 197 THR   A HG1  1 
ATOM   2956  H  HG21 . THR   A 1 198 ? -6.536  24.286  7.505   1.00 47.22 ? 197 THR   A HG21 1 
ATOM   2957  H  HG22 . THR   A 1 198 ? -5.664  24.217  8.820   1.00 47.22 ? 197 THR   A HG22 1 
ATOM   2958  H  HG23 . THR   A 1 198 ? -7.190  23.814  8.863   1.00 47.22 ? 197 THR   A HG23 1 
ATOM   2959  N  N    . THR   A 1 199 ? -6.680  24.051  11.518  1.00 19.42 ? 198 THR   A N    1 
ATOM   2960  C  CA   . THR   A 1 199 ? -5.764  23.289  12.372  1.00 19.59 ? 198 THR   A CA   1 
ATOM   2961  C  C    . THR   A 1 199 ? -5.158  22.147  11.559  1.00 23.63 ? 198 THR   A C    1 
ATOM   2962  O  O    . THR   A 1 199 ? -5.893  21.406  10.901  1.00 24.89 ? 198 THR   A O    1 
ATOM   2963  C  CB   . THR   A 1 199 ? -6.449  22.722  13.617  1.00 26.94 ? 198 THR   A CB   1 
ATOM   2964  O  OG1  . THR   A 1 199 ? -6.857  23.794  14.474  1.00 24.39 ? 198 THR   A OG1  1 
ATOM   2965  C  CG2  . THR   A 1 199 ? -5.467  21.793  14.376  1.00 24.27 ? 198 THR   A CG2  1 
ATOM   2966  H  H    . THR   A 1 199 ? -7.368  23.606  11.258  1.00 23.31 ? 198 THR   A H    1 
ATOM   2967  H  HA   . THR   A 1 199 ? -5.060  23.885  12.670  1.00 23.51 ? 198 THR   A HA   1 
ATOM   2968  H  HB   . THR   A 1 199 ? -7.231  22.208  13.362  1.00 32.32 ? 198 THR   A HB   1 
ATOM   2969  H  HG1  . THR   A 1 199 ? -6.275  24.400  14.473  1.00 29.27 ? 198 THR   A HG1  1 
ATOM   2970  H  HG21 . THR   A 1 199 ? -5.716  21.742  15.312  1.00 29.13 ? 198 THR   A HG21 1 
ATOM   2971  H  HG22 . THR   A 1 199 ? -5.492  20.901  13.994  1.00 29.13 ? 198 THR   A HG22 1 
ATOM   2972  H  HG23 . THR   A 1 199 ? -4.564  22.139  14.308  1.00 29.13 ? 198 THR   A HG23 1 
ATOM   2973  N  N    . LEU   A 1 200 ? -3.823  22.002  11.595  1.00 19.34 ? 199 LEU   A N    1 
ATOM   2974  C  CA   . LEU   A 1 200 ? -3.112  20.951  10.917  1.00 22.98 ? 199 LEU   A CA   1 
ATOM   2975  C  C    . LEU   A 1 200 ? -2.479  20.034  11.941  1.00 27.17 ? 199 LEU   A C    1 
ATOM   2976  O  O    . LEU   A 1 200 ? -2.124  20.444  12.983  1.00 21.34 ? 199 LEU   A O    1 
ATOM   2977  C  CB   . LEU   A 1 200 ? -2.013  21.494  10.041  1.00 22.25 ? 199 LEU   A CB   1 
ATOM   2978  C  CG   . LEU   A 1 200 ? -2.378  22.535  9.016   1.00 27.26 ? 199 LEU   A CG   1 
ATOM   2979  C  CD1  . LEU   A 1 200 ? -1.166  23.121  8.362   1.00 29.18 ? 199 LEU   A CD1  1 
ATOM   2980  C  CD2  . LEU   A 1 200 ? -3.257  21.920  7.965   1.00 32.50 ? 199 LEU   A CD2  1 
ATOM   2981  H  H    . LEU   A 1 200 ? -3.253  22.491  12.016  1.00 23.21 ? 199 LEU   A H    1 
ATOM   2982  H  HA   . LEU   A 1 200 ? -3.743  20.450  10.359  1.00 27.57 ? 199 LEU   A HA   1 
ATOM   2983  H  HB2  . LEU   A 1 200 ? -1.339  21.888  10.617  1.00 26.70 ? 199 LEU   A HB2  1 
ATOM   2984  H  HB3  . LEU   A 1 200 ? -1.622  20.750  9.558   1.00 26.70 ? 199 LEU   A HB3  1 
ATOM   2985  H  HG   . LEU   A 1 200 ? -2.871  23.253  9.445   1.00 32.71 ? 199 LEU   A HG   1 
ATOM   2986  H  HD11 . LEU   A 1 200 ? -1.418  23.921  7.894   1.00 35.02 ? 199 LEU   A HD11 1 
ATOM   2987  H  HD12 . LEU   A 1 200 ? -0.517  23.328  9.038   1.00 35.02 ? 199 LEU   A HD12 1 
ATOM   2988  H  HD13 . LEU   A 1 200 ? -0.804  22.481  7.745   1.00 35.02 ? 199 LEU   A HD13 1 
ATOM   2989  H  HD21 . LEU   A 1 200 ? -3.170  22.422  7.151   1.00 39.01 ? 199 LEU   A HD21 1 
ATOM   2990  H  HD22 . LEU   A 1 200 ? -2.981  21.012  7.821   1.00 39.01 ? 199 LEU   A HD22 1 
ATOM   2991  H  HD23 . LEU   A 1 200 ? -4.168  21.941  8.267   1.00 39.01 ? 199 LEU   A HD23 1 
ATOM   2992  N  N    . LYS   A 1 201 ? -2.354  18.768  11.618  1.00 24.23 ? 200 LYS   A N    1 
ATOM   2993  C  CA   . LYS   A 1 201 ? -1.756  17.831  12.548  1.00 29.51 ? 200 LYS   A CA   1 
ATOM   2994  C  C    . LYS   A 1 201 ? -0.732  16.963  11.853  1.00 28.48 ? 200 LYS   A C    1 
ATOM   2995  O  O    . LYS   A 1 201 ? -0.697  16.881  10.670  1.00 28.10 ? 200 LYS   A O    1 
ATOM   2996  C  CB   . LYS   A 1 201 ? -2.818  16.898  13.163  1.00 45.13 ? 200 LYS   A CB   1 
ATOM   2997  C  CG   . LYS   A 1 201 ? -3.903  17.534  14.010  1.00 53.83 ? 200 LYS   A CG   1 
ATOM   2998  C  CD   . LYS   A 1 201 ? -3.744  17.286  15.507  1.00 54.12 ? 200 LYS   A CD   1 
ATOM   2999  C  CE   . LYS   A 1 201 ? -4.763  16.268  16.005  1.00 61.40 ? 200 LYS   A CE   1 
ATOM   3000  N  NZ   . LYS   A 1 201 ? -4.471  15.709  17.352  1.00 68.19 ? 200 LYS   A NZ   1 
ATOM   3001  H  H    . LYS   A 1 201 ? -2.594  18.412  10.872  1.00 29.07 ? 200 LYS   A H    1 
ATOM   3002  H  HA   . LYS   A 1 201 ? -1.313  18.322  13.271  1.00 35.41 ? 200 LYS   A HA   1 
ATOM   3003  H  HB2  . LYS   A 1 201 ? -3.266  16.437  12.438  1.00 54.15 ? 200 LYS   A HB2  1 
ATOM   3004  H  HB3  . LYS   A 1 201 ? -2.393  16.245  13.739  1.00 54.15 ? 200 LYS   A HB3  1 
ATOM   3005  H  HG2  . LYS   A 1 201 ? -3.938  18.487  13.892  1.00 64.60 ? 200 LYS   A HG2  1 
ATOM   3006  H  HG3  . LYS   A 1 201 ? -4.753  17.149  13.746  1.00 64.60 ? 200 LYS   A HG3  1 
ATOM   3007  H  HD2  . LYS   A 1 201 ? -2.854  16.941  15.683  1.00 64.94 ? 200 LYS   A HD2  1 
ATOM   3008  H  HD3  . LYS   A 1 201 ? -3.883  18.118  15.986  1.00 64.94 ? 200 LYS   A HD3  1 
ATOM   3009  H  HE2  . LYS   A 1 201 ? -5.635  16.691  16.044  1.00 73.67 ? 200 LYS   A HE2  1 
ATOM   3010  H  HE3  . LYS   A 1 201 ? -4.789  15.525  15.381  1.00 73.67 ? 200 LYS   A HE3  1 
ATOM   3011  H  HZ1  . LYS   A 1 201 ? -3.522  15.651  17.486  1.00 81.83 ? 200 LYS   A HZ1  1 
ATOM   3012  H  HZ2  . LYS   A 1 201 ? -4.847  16.276  18.030  1.00 81.83 ? 200 LYS   A HZ2  1 
ATOM   3013  H  HZ3  . LYS   A 1 201 ? -4.852  14.831  17.435  1.00 81.83 ? 200 LYS   A HZ3  1 
ATOM   3014  N  N    . GLY   A 1 202 ? 0.111   16.329  12.625  1.00 26.86 ? 201 GLY   A N    1 
ATOM   3015  C  CA   . GLY   A 1 202 ? 1.061   15.419  12.061  1.00 30.07 ? 201 GLY   A CA   1 
ATOM   3016  C  C    . GLY   A 1 202 ? 2.139   16.062  11.242  1.00 27.49 ? 201 GLY   A C    1 
ATOM   3017  O  O    . GLY   A 1 202 ? 2.544   17.123  11.579  1.00 25.41 ? 201 GLY   A O    1 
ATOM   3018  H  H    . GLY   A 1 202 ? 0.153   16.408  13.481  1.00 32.23 ? 201 GLY   A H    1 
ATOM   3019  H  HA2  . GLY   A 1 202 ? 1.492   14.937  12.784  1.00 36.08 ? 201 GLY   A HA2  1 
ATOM   3020  H  HA3  . GLY   A 1 202 ? 0.560   14.775  11.537  1.00 36.08 ? 201 GLY   A HA3  1 
ATOM   3021  N  N    . VAL   A 1 203 ? 2.542   15.471  10.131  1.00 23.96 ? 202 VAL   A N    1 
ATOM   3022  C  CA   . VAL   A 1 203 ? 3.665   16.021  9.359   1.00 21.90 ? 202 VAL   A CA   1 
ATOM   3023  C  C    . VAL   A 1 203 ? 3.348   17.412  8.831   1.00 21.70 ? 202 VAL   A C    1 
ATOM   3024  O  O    . VAL   A 1 203 ? 4.231   18.275  8.732   1.00 23.49 ? 202 VAL   A O    1 
ATOM   3025  C  CB   . VAL   A 1 203 ? 4.044   15.084  8.189   1.00 27.96 ? 202 VAL   A CB   1 
ATOM   3026  C  CG1  . VAL   A 1 203 ? 5.156   15.699  7.331   1.00 28.36 ? 202 VAL   A CG1  1 
ATOM   3027  C  CG2  . VAL   A 1 203 ? 4.434   13.717  8.733   1.00 34.20 ? 202 VAL   A CG2  1 
ATOM   3028  H  H    . VAL   A 1 203 ? 2.201   14.752  9.803   1.00 28.76 ? 202 VAL   A H    1 
ATOM   3029  H  HA   . VAL   A 1 203 ? 4.418   16.086  9.967   1.00 26.29 ? 202 VAL   A HA   1 
ATOM   3030  H  HB   . VAL   A 1 203 ? 3.279   14.966  7.606   1.00 33.55 ? 202 VAL   A HB   1 
ATOM   3031  H  HG11 . VAL   A 1 203 ? 5.609   14.991  6.846   1.00 34.03 ? 202 VAL   A HG11 1 
ATOM   3032  H  HG12 . VAL   A 1 203 ? 4.761   16.328  6.707   1.00 34.03 ? 202 VAL   A HG12 1 
ATOM   3033  H  HG13 . VAL   A 1 203 ? 5.785   16.158  7.910   1.00 34.03 ? 202 VAL   A HG13 1 
ATOM   3034  H  HG21 . VAL   A 1 203 ? 4.866   13.208  8.029   1.00 41.04 ? 202 VAL   A HG21 1 
ATOM   3035  H  HG22 . VAL   A 1 203 ? 5.044   13.835  9.478   1.00 41.04 ? 202 VAL   A HG22 1 
ATOM   3036  H  HG23 . VAL   A 1 203 ? 3.634   13.256  9.031   1.00 41.04 ? 202 VAL   A HG23 1 
ATOM   3037  N  N    . GLU   A 1 204 ? 2.095   17.645  8.430   1.00 20.83 ? 203 GLU   A N    1 
ATOM   3038  C  CA   . GLU   A 1 204 ? 1.714   18.961  7.937   1.00 20.01 ? 203 GLU   A CA   1 
ATOM   3039  C  C    . GLU   A 1 204 ? 1.845   20.033  9.010   1.00 21.99 ? 203 GLU   A C    1 
ATOM   3040  O  O    . GLU   A 1 204 ? 1.882   21.226  8.684   1.00 24.43 ? 203 GLU   A O    1 
ATOM   3041  C  CB   . GLU   A 1 204 ? 0.278   18.939  7.428   1.00 27.54 ? 203 GLU   A CB   1 
ATOM   3042  C  CG   . GLU   A 1 204 ? 0.114   18.091  6.173   1.00 33.53 ? 203 GLU   A CG   1 
ATOM   3043  C  CD   . GLU   A 1 204 ? -1.187  18.369  5.455   1.00 47.36 ? 203 GLU   A CD   1 
ATOM   3044  O  OE1  . GLU   A 1 204 ? -1.170  18.465  4.208   1.00 56.37 ? 203 GLU   A OE1  1 
ATOM   3045  O  OE2  . GLU   A 1 204 ? -2.223  18.508  6.143   1.00 55.60 ? 203 GLU   A OE2  1 
ATOM   3046  H  H    . GLU   A 1 204 ? 1.460   17.065  8.435   1.00 24.99 ? 203 GLU   A H    1 
ATOM   3047  H  HA   . GLU   A 1 204 ? 2.298   19.190  7.197   1.00 24.01 ? 203 GLU   A HA   1 
ATOM   3048  H  HB2  . GLU   A 1 204 ? -0.296  18.571  8.117   1.00 33.05 ? 203 GLU   A HB2  1 
ATOM   3049  H  HB3  . GLU   A 1 204 ? 0.003   19.845  7.217   1.00 33.05 ? 203 GLU   A HB3  1 
ATOM   3050  H  HG2  . GLU   A 1 204 ? 0.842   18.284  5.562   1.00 40.23 ? 203 GLU   A HG2  1 
ATOM   3051  H  HG3  . GLU   A 1 204 ? 0.127   17.153  6.420   1.00 40.23 ? 203 GLU   A HG3  1 
ATOM   3052  N  N    . ALA   A 1 205 ? 1.858   19.645  10.282  1.00 17.52 ? 204 ALA   A N    1 
ATOM   3053  C  CA   . ALA   A 1 205 ? 1.989   20.623  11.342  1.00 18.35 ? 204 ALA   A CA   1 
ATOM   3054  C  C    . ALA   A 1 205 ? 3.426   21.087  11.551  1.00 18.62 ? 204 ALA   A C    1 
ATOM   3055  O  O    . ALA   A 1 205 ? 3.625   22.079  12.253  1.00 21.49 ? 204 ALA   A O    1 
ATOM   3056  C  CB   . ALA   A 1 205 ? 1.448   20.076  12.683  1.00 21.26 ? 204 ALA   A CB   1 
ATOM   3057  H  H    . ALA   A 1 205 ? 1.792   18.830  10.548  1.00 21.02 ? 204 ALA   A H    1 
ATOM   3058  H  HA   . ALA   A 1 205 ? 1.446   21.388  11.097  1.00 22.02 ? 204 ALA   A HA   1 
ATOM   3059  H  HB1  . ALA   A 1 205 ? 1.163   20.820  13.235  1.00 25.51 ? 204 ALA   A HB1  1 
ATOM   3060  H  HB2  . ALA   A 1 205 ? 0.696   19.490  12.504  1.00 25.51 ? 204 ALA   A HB2  1 
ATOM   3061  H  HB3  . ALA   A 1 205 ? 2.153   19.582  13.130  1.00 25.51 ? 204 ALA   A HB3  1 
ATOM   3062  N  N    . VAL   A 1 206 ? 4.428   20.394  11.000  1.00 16.27 ? 205 VAL   A N    1 
ATOM   3063  C  CA   . VAL   A 1 206 ? 5.827   20.753  11.252  1.00 19.55 ? 205 VAL   A CA   1 
ATOM   3064  C  C    . VAL   A 1 206 ? 6.561   21.264  10.027  1.00 19.97 ? 205 VAL   A C    1 
ATOM   3065  O  O    . VAL   A 1 206 ? 7.734   21.638  10.144  1.00 20.65 ? 205 VAL   A O    1 
ATOM   3066  C  CB   . VAL   A 1 206 ? 6.623   19.598  11.892  1.00 16.55 ? 205 VAL   A CB   1 
ATOM   3067  C  CG1  . VAL   A 1 206 ? 5.949   19.117  13.192  1.00 21.74 ? 205 VAL   A CG1  1 
ATOM   3068  C  CG2  . VAL   A 1 206 ? 6.778   18.423  10.942  1.00 20.40 ? 205 VAL   A CG2  1 
ATOM   3069  H  H    . VAL   A 1 206 ? 4.322   19.717  10.480  1.00 19.52 ? 205 VAL   A H    1 
ATOM   3070  H  HA   . VAL   A 1 206 ? 5.802   21.485  11.888  1.00 23.46 ? 205 VAL   A HA   1 
ATOM   3071  H  HB   . VAL   A 1 206 ? 7.507   19.941  12.099  1.00 19.86 ? 205 VAL   A HB   1 
ATOM   3072  H  HG11 . VAL   A 1 206 ? 6.608   18.664  13.741  1.00 26.08 ? 205 VAL   A HG11 1 
ATOM   3073  H  HG12 . VAL   A 1 206 ? 5.594   19.884  13.667  1.00 26.08 ? 205 VAL   A HG12 1 
ATOM   3074  H  HG13 . VAL   A 1 206 ? 5.230   18.506  12.967  1.00 26.08 ? 205 VAL   A HG13 1 
ATOM   3075  H  HG21 . VAL   A 1 206 ? 6.468   17.617  11.384  1.00 24.48 ? 205 VAL   A HG21 1 
ATOM   3076  H  HG22 . VAL   A 1 206 ? 6.249   18.589  10.146  1.00 24.48 ? 205 VAL   A HG22 1 
ATOM   3077  H  HG23 . VAL   A 1 206 ? 7.714   18.331  10.704  1.00 24.48 ? 205 VAL   A HG23 1 
ATOM   3078  N  N    . MET   A 1 207 ? 5.927   21.316  8.875   1.00 18.08 ? 206 MET   A N    1 
ATOM   3079  C  CA   . MET   A 1 207 ? 6.591   21.742  7.654   1.00 19.83 ? 206 MET   A CA   1 
ATOM   3080  C  C    . MET   A 1 207 ? 5.875   22.950  7.076   1.00 20.65 ? 206 MET   A C    1 
ATOM   3081  O  O    . MET   A 1 207 ? 4.649   23.056  7.140   1.00 21.16 ? 206 MET   A O    1 
ATOM   3082  C  CB   . MET   A 1 207 ? 6.619   20.606  6.621   1.00 18.64 ? 206 MET   A CB   1 
ATOM   3083  C  CG   . MET   A 1 207 ? 7.535   19.437  7.011   1.00 21.81 ? 206 MET   A CG   1 
ATOM   3084  S  SD   . MET   A 1 207 ? 7.559   18.117  5.752   1.00 30.43 ? 206 MET   A SD   1 
ATOM   3085  C  CE   . MET   A 1 207 ? 5.971   18.379  4.973   1.00 35.52 ? 206 MET   A CE   1 
ATOM   3086  H  H    . MET   A 1 207 ? 5.099   21.108  8.770   1.00 21.70 ? 206 MET   A H    1 
ATOM   3087  H  HA   . MET   A 1 207 ? 7.508   21.988  7.852   1.00 23.79 ? 206 MET   A HA   1 
ATOM   3088  H  HB2  . MET   A 1 207 ? 5.720   20.256  6.517   1.00 22.37 ? 206 MET   A HB2  1 
ATOM   3089  H  HB3  . MET   A 1 207 ? 6.936   20.961  5.775   1.00 22.37 ? 206 MET   A HB3  1 
ATOM   3090  H  HG2  . MET   A 1 207 ? 8.440   19.766  7.118   1.00 26.17 ? 206 MET   A HG2  1 
ATOM   3091  H  HG3  . MET   A 1 207 ? 7.220   19.052  7.844   1.00 26.17 ? 206 MET   A HG3  1 
ATOM   3092  H  HE1  . MET   A 1 207 ? 5.342   18.701  5.638   1.00 42.62 ? 206 MET   A HE1  1 
ATOM   3093  H  HE2  . MET   A 1 207 ? 6.071   19.037  4.267   1.00 42.62 ? 206 MET   A HE2  1 
ATOM   3094  H  HE3  . MET   A 1 207 ? 5.659   17.539  4.601   1.00 42.62 ? 206 MET   A HE3  1 
ATOM   3095  N  N    . TYR   A 1 208 ? 6.658   23.834  6.476   1.00 20.16 ? 207 TYR   A N    1 
ATOM   3096  C  CA   . TYR   A 1 208 ? 6.124   24.964  5.743   1.00 16.23 ? 207 TYR   A CA   1 
ATOM   3097  C  C    . TYR   A 1 208 ? 7.032   25.275  4.558   1.00 20.25 ? 207 TYR   A C    1 
ATOM   3098  O  O    . TYR   A 1 208 ? 8.264   25.203  4.664   1.00 19.63 ? 207 TYR   A O    1 
ATOM   3099  C  CB   . TYR   A 1 208 ? 5.996   26.192  6.639   1.00 17.92 ? 207 TYR   A CB   1 
ATOM   3100  C  CG   . TYR   A 1 208 ? 5.261   27.284  5.930   1.00 20.82 ? 207 TYR   A CG   1 
ATOM   3101  C  CD1  . TYR   A 1 208 ? 3.878   27.249  5.824   1.00 26.14 ? 207 TYR   A CD1  1 
ATOM   3102  C  CD2  . TYR   A 1 208 ? 5.943   28.304  5.291   1.00 22.52 ? 207 TYR   A CD2  1 
ATOM   3103  C  CE1  . TYR   A 1 208 ? 3.182   28.231  5.119   1.00 30.81 ? 207 TYR   A CE1  1 
ATOM   3104  C  CE2  . TYR   A 1 208 ? 5.255   29.294  4.591   1.00 21.26 ? 207 TYR   A CE2  1 
ATOM   3105  C  CZ   . TYR   A 1 208 ? 3.882   29.246  4.506   1.00 28.21 ? 207 TYR   A CZ   1 
ATOM   3106  O  OH   . TYR   A 1 208 ? 3.207   30.222  3.802   1.00 27.96 ? 207 TYR   A OH   1 
ATOM   3107  H  H    . TYR   A 1 208 ? 7.518   23.798  6.480   1.00 24.19 ? 207 TYR   A H    1 
ATOM   3108  H  HA   . TYR   A 1 208 ? 5.246   24.739  5.398   1.00 19.47 ? 207 TYR   A HA   1 
ATOM   3109  H  HB2  . TYR   A 1 208 ? 5.505   25.957  7.441   1.00 21.51 ? 207 TYR   A HB2  1 
ATOM   3110  H  HB3  . TYR   A 1 208 ? 6.880   26.515  6.874   1.00 21.51 ? 207 TYR   A HB3  1 
ATOM   3111  H  HD1  . TYR   A 1 208 ? 3.407   26.558  6.230   1.00 31.36 ? 207 TYR   A HD1  1 
ATOM   3112  H  HD2  . TYR   A 1 208 ? 6.872   28.329  5.329   1.00 27.03 ? 207 TYR   A HD2  1 
ATOM   3113  H  HE1  . TYR   A 1 208 ? 2.254   28.200  5.063   1.00 36.97 ? 207 TYR   A HE1  1 
ATOM   3114  H  HE2  . TYR   A 1 208 ? 5.723   29.987  4.183   1.00 25.51 ? 207 TYR   A HE2  1 
ATOM   3115  H  HH   . TYR   A 1 208 ? 2.609   30.563  4.283   1.00 33.55 ? 207 TYR   A HH   1 
ATOM   3116  N  N    . MET   A 1 209 ? 6.417   25.618  3.427   1.00 21.38 ? 208 MET   A N    1 
ATOM   3117  C  CA   . MET   A 1 209 ? 7.153   25.961  2.207   1.00 17.91 ? 208 MET   A CA   1 
ATOM   3118  C  C    . MET   A 1 209 ? 6.735   27.351  1.758   1.00 22.47 ? 208 MET   A C    1 
ATOM   3119  O  O    . MET   A 1 209 ? 5.552   27.586  1.474   1.00 23.38 ? 208 MET   A O    1 
ATOM   3120  C  CB   . MET   A 1 209 ? 6.884   24.944  1.101   1.00 21.95 ? 208 MET   A CB   1 
ATOM   3121  C  CG   . MET   A 1 209 ? 7.693   25.011  -0.194  1.00 24.02 ? 208 MET   A CG   1 
ATOM   3122  S  SD   . MET   A 1 209 ? 9.462   25.146  0.054   1.00 23.49 ? 208 MET   A SD   1 
ATOM   3123  C  CE   . MET   A 1 209 ? 10.152  25.116  -1.631  1.00 30.95 ? 208 MET   A CE   1 
ATOM   3124  H  H    . MET   A 1 209 ? 5.563   25.661  3.340   1.00 25.66 ? 208 MET   A H    1 
ATOM   3125  H  HA   . MET   A 1 209 ? 8.104   25.957  2.399   1.00 21.49 ? 208 MET   A HA   1 
ATOM   3126  H  HB2  . MET   A 1 209 ? 7.041   24.062  1.473   1.00 26.34 ? 208 MET   A HB2  1 
ATOM   3127  H  HB3  . MET   A 1 209 ? 5.953   25.035  0.844   1.00 26.34 ? 208 MET   A HB3  1 
ATOM   3128  H  HG2  . MET   A 1 209 ? 7.529   24.203  -0.705  1.00 28.82 ? 208 MET   A HG2  1 
ATOM   3129  H  HG3  . MET   A 1 209 ? 7.407   25.788  -0.699  1.00 28.82 ? 208 MET   A HG3  1 
ATOM   3130  H  HE1  . MET   A 1 209 ? 11.111  25.256  -1.583  1.00 37.14 ? 208 MET   A HE1  1 
ATOM   3131  H  HE2  . MET   A 1 209 ? 9.963   24.254  -2.034  1.00 37.14 ? 208 MET   A HE2  1 
ATOM   3132  H  HE3  . MET   A 1 209 ? 9.741   25.823  -2.153  1.00 37.14 ? 208 MET   A HE3  1 
ATOM   3133  N  N    . GLY   A 1 210 ? 7.688   28.271  1.741   1.00 20.75 ? 209 GLY   A N    1 
ATOM   3134  C  CA   . GLY   A 1 210 ? 7.395   29.647  1.371   1.00 23.97 ? 209 GLY   A CA   1 
ATOM   3135  C  C    . GLY   A 1 210 ? 8.173   30.731  2.096   1.00 26.51 ? 209 GLY   A C    1 
ATOM   3136  O  O    . GLY   A 1 210 ? 8.386   31.819  1.529   1.00 23.54 ? 209 GLY   A O    1 
ATOM   3137  H  H    . GLY   A 1 210 ? 8.512   28.124  1.939   1.00 24.90 ? 209 GLY   A H    1 
ATOM   3138  H  HA2  . GLY   A 1 210 ? 7.573   29.751  0.423   1.00 28.76 ? 209 GLY   A HA2  1 
ATOM   3139  H  HA3  . GLY   A 1 210 ? 6.453   29.812  1.535   1.00 28.76 ? 209 GLY   A HA3  1 
ATOM   3140  N  N    . THR   A 1 211 ? 8.602   30.462  3.335   1.00 19.05 ? 210 THR   A N    1 
ATOM   3141  C  CA   . THR   A 1 211 ? 9.496   31.349  4.066   1.00 21.06 ? 210 THR   A CA   1 
ATOM   3142  C  C    . THR   A 1 211 ? 10.430  30.522  4.943   1.00 19.14 ? 210 THR   A C    1 
ATOM   3143  O  O    . THR   A 1 211 ? 10.056  29.472  5.463   1.00 17.66 ? 210 THR   A O    1 
ATOM   3144  C  CB   . THR   A 1 211 ? 8.768   32.383  4.936   1.00 23.71 ? 210 THR   A CB   1 
ATOM   3145  O  OG1  . THR   A 1 211 ? 9.725   33.314  5.472   1.00 25.13 ? 210 THR   A OG1  1 
ATOM   3146  C  CG2  . THR   A 1 211 ? 8.084   31.761  6.091   1.00 22.80 ? 210 THR   A CG2  1 
ATOM   3147  H  H    . THR   A 1 211 ? 8.382   29.757  3.777   1.00 22.86 ? 210 THR   A H    1 
ATOM   3148  H  HA   . THR   A 1 211 ? 10.018  31.837  3.410   1.00 25.28 ? 210 THR   A HA   1 
ATOM   3149  H  HB   . THR   A 1 211 ? 8.107   32.824  4.380   1.00 28.45 ? 210 THR   A HB   1 
ATOM   3150  H  HG1  . THR   A 1 211 ? 9.547   33.479  6.276   1.00 30.16 ? 210 THR   A HG1  1 
ATOM   3151  H  HG21 . THR   A 1 211 ? 7.359   32.330  6.393   1.00 27.37 ? 210 THR   A HG21 1 
ATOM   3152  H  HG22 . THR   A 1 211 ? 7.721   30.898  5.836   1.00 27.37 ? 210 THR   A HG22 1 
ATOM   3153  H  HG23 . THR   A 1 211 ? 8.711   31.636  6.820   1.00 27.37 ? 210 THR   A HG23 1 
ATOM   3154  N  N    . LEU   A 1 212 ? 11.649  31.019  5.096   1.00 17.04 ? 211 LEU   A N    1 
ATOM   3155  C  CA   . LEU   A 1 212 ? 12.644  30.416  5.967   1.00 16.55 ? 211 LEU   A CA   1 
ATOM   3156  C  C    . LEU   A 1 212 ? 12.522  30.890  7.407   1.00 15.76 ? 211 LEU   A C    1 
ATOM   3157  O  O    . LEU   A 1 212 ? 13.062  30.240  8.294   1.00 18.01 ? 211 LEU   A O    1 
ATOM   3158  C  CB   . LEU   A 1 212 ? 14.042  30.768  5.458   1.00 18.33 ? 211 LEU   A CB   1 
ATOM   3159  C  CG   . LEU   A 1 212 ? 14.402  30.251  4.063   1.00 18.48 ? 211 LEU   A CG   1 
ATOM   3160  C  CD1  . LEU   A 1 212 ? 15.759  30.816  3.719   1.00 20.37 ? 211 LEU   A CD1  1 
ATOM   3161  C  CD2  . LEU   A 1 212 ? 14.459  28.730  4.000   1.00 18.58 ? 211 LEU   A CD2  1 
ATOM   3162  H  H    . LEU   A 1 212 ? 11.932  31.726  4.695   1.00 20.44 ? 211 LEU   A H    1 
ATOM   3163  H  HA   . LEU   A 1 212 ? 12.538  29.452  5.952   1.00 19.86 ? 211 LEU   A HA   1 
ATOM   3164  H  HB2  . LEU   A 1 212 ? 14.120  31.735  5.434   1.00 21.99 ? 211 LEU   A HB2  1 
ATOM   3165  H  HB3  . LEU   A 1 212 ? 14.691  30.398  6.077   1.00 21.99 ? 211 LEU   A HB3  1 
ATOM   3166  H  HG   . LEU   A 1 212 ? 13.722  30.526  3.428   1.00 22.17 ? 211 LEU   A HG   1 
ATOM   3167  H  HD11 . LEU   A 1 212 ? 16.265  30.148  3.231   1.00 24.44 ? 211 LEU   A HD11 1 
ATOM   3168  H  HD12 . LEU   A 1 212 ? 15.642  31.608  3.172   1.00 24.44 ? 211 LEU   A HD12 1 
ATOM   3169  H  HD13 . LEU   A 1 212 ? 16.222  31.047  4.540   1.00 24.44 ? 211 LEU   A HD13 1 
ATOM   3170  H  HD21 . LEU   A 1 212 ? 14.837  28.463  3.148   1.00 22.29 ? 211 LEU   A HD21 1 
ATOM   3171  H  HD22 . LEU   A 1 212 ? 15.014  28.405  4.726   1.00 22.29 ? 211 LEU   A HD22 1 
ATOM   3172  H  HD23 . LEU   A 1 212 ? 13.560  28.377  4.088   1.00 22.29 ? 211 LEU   A HD23 1 
ATOM   3173  N  N    . SER   A 1 213 ? 11.876  32.031  7.629   1.00 16.57 ? 212 SER   A N    1 
ATOM   3174  C  CA   . SER   A 1 213 ? 11.852  32.713  8.919   1.00 17.03 ? 212 SER   A CA   1 
ATOM   3175  C  C    . SER   A 1 213 ? 10.635  32.294  9.750   1.00 14.61 ? 212 SER   A C    1 
ATOM   3176  O  O    . SER   A 1 213 ? 9.486   32.577  9.367   1.00 18.07 ? 212 SER   A O    1 
ATOM   3177  C  CB   . SER   A 1 213 ? 11.813  34.231  8.711   1.00 21.70 ? 212 SER   A CB   1 
ATOM   3178  O  OG   . SER   A 1 213 ? 11.652  34.905  9.957   1.00 20.34 ? 212 SER   A OG   1 
ATOM   3179  H  H    . SER   A 1 213 ? 11.427  32.447  7.024   1.00 19.88 ? 212 SER   A H    1 
ATOM   3180  H  HA   . SER   A 1 213 ? 12.651  32.454  9.405   1.00 20.44 ? 212 SER   A HA   1 
ATOM   3181  H  HB2  . SER   A 1 213 ? 12.645  34.516  8.303   1.00 26.04 ? 212 SER   A HB2  1 
ATOM   3182  H  HB3  . SER   A 1 213 ? 11.066  34.452  8.133   1.00 26.04 ? 212 SER   A HB3  1 
ATOM   3183  H  HG   . SER   A 1 213 ? 11.567  35.731  9.829   1.00 24.41 ? 212 SER   A HG   1 
ATOM   3184  N  N    . TYR   A 1 214 ? 10.904  31.654  10.885  1.00 18.43 ? 213 TYR   A N    1 
ATOM   3185  C  CA   . TYR   A 1 214 ? 9.852   31.304  11.846  1.00 20.27 ? 213 TYR   A CA   1 
ATOM   3186  C  C    . TYR   A 1 214 ? 9.243   32.572  12.426  1.00 22.67 ? 213 TYR   A C    1 
ATOM   3187  O  O    . TYR   A 1 214 ? 8.015   32.700  12.524  1.00 18.20 ? 213 TYR   A O    1 
ATOM   3188  C  CB   . TYR   A 1 214 ? 10.471  30.383  12.907  1.00 19.24 ? 213 TYR   A CB   1 
ATOM   3189  C  CG   . TYR   A 1 214 ? 9.534   29.643  13.851  1.00 18.29 ? 213 TYR   A CG   1 
ATOM   3190  C  CD1  . TYR   A 1 214 ? 8.247   29.300  13.473  1.00 17.23 ? 213 TYR   A CD1  1 
ATOM   3191  C  CD2  . TYR   A 1 214 ? 9.969   29.253  15.108  1.00 19.82 ? 213 TYR   A CD2  1 
ATOM   3192  C  CE1  . TYR   A 1 214 ? 7.418   28.625  14.307  1.00 19.62 ? 213 TYR   A CE1  1 
ATOM   3193  C  CE2  . TYR   A 1 214 ? 9.125   28.584  15.979  1.00 21.15 ? 213 TYR   A CE2  1 
ATOM   3194  C  CZ   . TYR   A 1 214 ? 7.851   28.264  15.563  1.00 25.02 ? 213 TYR   A CZ   1 
ATOM   3195  O  OH   . TYR   A 1 214 ? 7.003   27.590  16.401  1.00 22.13 ? 213 TYR   A OH   1 
ATOM   3196  H  H    . TYR   A 1 214 ? 11.691  31.408  11.129  1.00 22.11 ? 213 TYR   A H    1 
ATOM   3197  H  HA   . TYR   A 1 214 ? 9.125   30.814  11.432  1.00 24.32 ? 213 TYR   A HA   1 
ATOM   3198  H  HB2  . TYR   A 1 214 ? 10.989  29.707  12.444  1.00 23.09 ? 213 TYR   A HB2  1 
ATOM   3199  H  HB3  . TYR   A 1 214 ? 11.054  30.925  13.463  1.00 23.09 ? 213 TYR   A HB3  1 
ATOM   3200  H  HD1  . TYR   A 1 214 ? 7.943   29.538  12.627  1.00 20.68 ? 213 TYR   A HD1  1 
ATOM   3201  H  HD2  . TYR   A 1 214 ? 10.840  29.443  15.371  1.00 23.78 ? 213 TYR   A HD2  1 
ATOM   3202  H  HE1  . TYR   A 1 214 ? 6.558   28.406  14.030  1.00 23.54 ? 213 TYR   A HE1  1 
ATOM   3203  H  HE2  . TYR   A 1 214 ? 9.414   28.353  16.832  1.00 25.38 ? 213 TYR   A HE2  1 
ATOM   3204  H  HH   . TYR   A 1 214 ? 7.269   26.800  16.505  1.00 26.55 ? 213 TYR   A HH   1 
ATOM   3205  N  N    . GLU   A 1 215 ? 10.076  33.569  12.708  1.00 18.87 ? 214 GLU   A N    1 
ATOM   3206  C  CA   . GLU   A 1 215 ? 9.539   34.837  13.206  1.00 23.29 ? 214 GLU   A CA   1 
ATOM   3207  C  C    . GLU   A 1 215 ? 8.598   35.488  12.183  1.00 21.76 ? 214 GLU   A C    1 
ATOM   3208  O  O    . GLU   A 1 215 ? 7.544   36.042  12.559  1.00 21.72 ? 214 GLU   A O    1 
ATOM   3209  C  CB   . GLU   A 1 215 ? 10.696  35.760  13.595  1.00 25.04 ? 214 GLU   A CB   1 
ATOM   3210  C  CG   . GLU   A 1 215 ? 11.480  35.237  14.808  1.00 39.72 ? 214 GLU   A CG   1 
ATOM   3211  C  CD   . GLU   A 1 215 ? 10.580  34.913  15.999  1.00 49.47 ? 214 GLU   A CD   1 
ATOM   3212  O  OE1  . GLU   A 1 215 ? 9.880   35.853  16.450  1.00 42.44 ? 214 GLU   A OE1  1 
ATOM   3213  O  OE2  . GLU   A 1 215 ? 10.535  33.708  16.421  1.00 41.07 ? 214 GLU   A OE2  1 
ATOM   3214  H  H    . GLU   A 1 215 ? 10.932  33.541  12.624  1.00 22.64 ? 214 GLU   A H    1 
ATOM   3215  H  HA   . GLU   A 1 215 ? 9.011   34.679  14.004  1.00 27.95 ? 214 GLU   A HA   1 
ATOM   3216  H  HB2  . GLU   A 1 215 ? 11.310  35.832  12.847  1.00 30.05 ? 214 GLU   A HB2  1 
ATOM   3217  H  HB3  . GLU   A 1 215 ? 10.342  36.635  13.819  1.00 30.05 ? 214 GLU   A HB3  1 
ATOM   3218  H  HG2  . GLU   A 1 215 ? 11.948  34.426  14.556  1.00 47.66 ? 214 GLU   A HG2  1 
ATOM   3219  H  HG3  . GLU   A 1 215 ? 12.116  35.914  15.089  1.00 47.66 ? 214 GLU   A HG3  1 
ATOM   3220  N  N    . GLN   A 1 216 ? 8.922   35.403  10.877  1.00 21.44 ? 215 GLN   A N    1 
ATOM   3221  C  CA   . GLN   A 1 216 ? 8.040   36.001  9.879   1.00 21.71 ? 215 GLN   A CA   1 
ATOM   3222  C  C    . GLN   A 1 216 ? 6.700   35.264  9.816   1.00 21.48 ? 215 GLN   A C    1 
ATOM   3223  O  O    . GLN   A 1 216 ? 5.653   35.883  9.603   1.00 22.55 ? 215 GLN   A O    1 
ATOM   3224  C  CB   . GLN   A 1 216 ? 8.698   36.005  8.506   1.00 22.47 ? 215 GLN   A CB   1 
ATOM   3225  C  CG   . GLN   A 1 216 ? 7.956   36.816  7.463   1.00 30.02 ? 215 GLN   A CG   1 
ATOM   3226  C  CD   . GLN   A 1 216 ? 7.903   38.296  7.817   1.00 37.86 ? 215 GLN   A CD   1 
ATOM   3227  O  OE1  . GLN   A 1 216 ? 8.918   38.979  7.744   1.00 40.57 ? 215 GLN   A OE1  1 
ATOM   3228  N  NE2  . GLN   A 1 216 ? 6.721   38.795  8.192   1.00 39.47 ? 215 GLN   A NE2  1 
ATOM   3229  H  H    . GLN   A 1 216 ? 9.623   35.017  10.563  1.00 25.72 ? 215 GLN   A H    1 
ATOM   3230  H  HA   . GLN   A 1 216 ? 7.879   36.923  10.133  1.00 26.05 ? 215 GLN   A HA   1 
ATOM   3231  H  HB2  . GLN   A 1 216 ? 9.589   36.379  8.590   1.00 26.96 ? 215 GLN   A HB2  1 
ATOM   3232  H  HB3  . GLN   A 1 216 ? 8.750   35.091  8.185   1.00 26.96 ? 215 GLN   A HB3  1 
ATOM   3233  H  HG2  . GLN   A 1 216 ? 8.407   36.726  6.609   1.00 36.02 ? 215 GLN   A HG2  1 
ATOM   3234  H  HG3  . GLN   A 1 216 ? 7.046   36.489  7.393   1.00 36.02 ? 215 GLN   A HG3  1 
ATOM   3235  H  HE21 . GLN   A 1 216 ? 6.029   38.285  8.224   1.00 47.36 ? 215 GLN   A HE21 1 
ATOM   3236  H  HE22 . GLN   A 1 216 ? 6.652   39.627  8.399   1.00 47.36 ? 215 GLN   A HE22 1 
ATOM   3237  N  N    . PHE   A 1 217 ? 6.732   33.936  9.968   1.00 20.15 ? 216 PHE   A N    1 
ATOM   3238  C  CA   . PHE   A 1 217 ? 5.517   33.124  10.009  1.00 19.46 ? 216 PHE   A CA   1 
ATOM   3239  C  C    . PHE   A 1 217 ? 4.644   33.534  11.184  1.00 20.21 ? 216 PHE   A C    1 
ATOM   3240  O  O    . PHE   A 1 217 ? 3.412   33.549  11.087  1.00 22.53 ? 216 PHE   A O    1 
ATOM   3241  C  CB   . PHE   A 1 217 ? 5.938   31.648  10.129  1.00 19.07 ? 216 PHE   A CB   1 
ATOM   3242  C  CG   . PHE   A 1 217 ? 4.880   30.629  9.772   1.00 22.66 ? 216 PHE   A CG   1 
ATOM   3243  C  CD1  . PHE   A 1 217 ? 4.006   30.811  8.722   1.00 33.09 ? 216 PHE   A CD1  1 
ATOM   3244  C  CD2  . PHE   A 1 217 ? 4.836   29.424  10.465  1.00 23.50 ? 216 PHE   A CD2  1 
ATOM   3245  C  CE1  . PHE   A 1 217 ? 3.065   29.817  8.389   1.00 38.84 ? 216 PHE   A CE1  1 
ATOM   3246  C  CE2  . PHE   A 1 217 ? 3.893   28.434  10.144  1.00 24.84 ? 216 PHE   A CE2  1 
ATOM   3247  C  CZ   . PHE   A 1 217 ? 3.024   28.628  9.113   1.00 30.08 ? 216 PHE   A CZ   1 
ATOM   3248  H  H    . PHE   A 1 217 ? 7.454   33.476  10.052  1.00 24.18 ? 216 PHE   A H    1 
ATOM   3249  H  HA   . PHE   A 1 217 ? 4.996   33.240  9.199   1.00 23.35 ? 216 PHE   A HA   1 
ATOM   3250  H  HB2  . PHE   A 1 217 ? 6.692   31.498  9.538   1.00 22.89 ? 216 PHE   A HB2  1 
ATOM   3251  H  HB3  . PHE   A 1 217 ? 6.199   31.481  11.048  1.00 22.89 ? 216 PHE   A HB3  1 
ATOM   3252  H  HD1  . PHE   A 1 217 ? 4.038   31.598  8.228   1.00 39.71 ? 216 PHE   A HD1  1 
ATOM   3253  H  HD2  . PHE   A 1 217 ? 5.442   29.271  11.154  1.00 28.20 ? 216 PHE   A HD2  1 
ATOM   3254  H  HE1  . PHE   A 1 217 ? 2.472   29.954  7.686   1.00 46.61 ? 216 PHE   A HE1  1 
ATOM   3255  H  HE2  . PHE   A 1 217 ? 3.862   27.645  10.635  1.00 29.80 ? 216 PHE   A HE2  1 
ATOM   3256  H  HZ   . PHE   A 1 217 ? 2.406   27.969  8.893   1.00 36.09 ? 216 PHE   A HZ   1 
ATOM   3257  N  N    . LYS   A 1 218 ? 5.276   33.866  12.303  1.00 18.05 ? 217 LYS   A N    1 
ATOM   3258  C  CA   . LYS   A 1 218 ? 4.536   34.320  13.484  1.00 20.78 ? 217 LYS   A CA   1 
ATOM   3259  C  C    . LYS   A 1 218 ? 3.953   35.709  13.266  1.00 28.62 ? 217 LYS   A C    1 
ATOM   3260  O  O    . LYS   A 1 218 ? 2.850   36.015  13.743  1.00 26.10 ? 217 LYS   A O    1 
ATOM   3261  C  CB   . LYS   A 1 218 ? 5.441   34.309  14.713  1.00 21.48 ? 217 LYS   A CB   1 
ATOM   3262  C  CG   . LYS   A 1 218 ? 5.861   32.944  15.202  1.00 20.33 ? 217 LYS   A CG   1 
ATOM   3263  C  CD   . LYS   A 1 218 ? 7.014   33.053  16.177  1.00 23.06 ? 217 LYS   A CD   1 
ATOM   3264  C  CE   . LYS   A 1 218 ? 7.400   31.696  16.775  1.00 22.88 ? 217 LYS   A CE   1 
ATOM   3265  N  NZ   . LYS   A 1 218 ? 8.434   31.811  17.847  1.00 25.00 ? 217 LYS   A NZ   1 
ATOM   3266  H  H    . LYS   A 1 218 ? 6.129   33.840  12.409  1.00 21.66 ? 217 LYS   A H    1 
ATOM   3267  H  HA   . LYS   A 1 218 ? 3.805   33.704  13.647  1.00 24.94 ? 217 LYS   A HA   1 
ATOM   3268  H  HB2  . LYS   A 1 218 ? 6.250   34.800  14.501  1.00 25.77 ? 217 LYS   A HB2  1 
ATOM   3269  H  HB3  . LYS   A 1 218 ? 4.971   34.744  15.442  1.00 25.77 ? 217 LYS   A HB3  1 
ATOM   3270  H  HG2  . LYS   A 1 218 ? 5.115   32.519  15.654  1.00 24.39 ? 217 LYS   A HG2  1 
ATOM   3271  H  HG3  . LYS   A 1 218 ? 6.145   32.404  14.448  1.00 24.39 ? 217 LYS   A HG3  1 
ATOM   3272  H  HD2  . LYS   A 1 218 ? 7.788   33.410  15.715  1.00 27.68 ? 217 LYS   A HD2  1 
ATOM   3273  H  HD3  . LYS   A 1 218 ? 6.761   33.642  16.904  1.00 27.68 ? 217 LYS   A HD3  1 
ATOM   3274  H  HE2  . LYS   A 1 218 ? 6.611   31.285  17.161  1.00 27.46 ? 217 LYS   A HE2  1 
ATOM   3275  H  HE3  . LYS   A 1 218 ? 7.758   31.131  16.072  1.00 27.46 ? 217 LYS   A HE3  1 
ATOM   3276  H  HZ1  . LYS   A 1 218 ? 8.929   31.072  17.873  1.00 30.00 ? 217 LYS   A HZ1  1 
ATOM   3277  H  HZ2  . LYS   A 1 218 ? 8.963   32.508  17.686  1.00 30.00 ? 217 LYS   A HZ2  1 
ATOM   3278  H  HZ3  . LYS   A 1 218 ? 8.041   31.923  18.638  1.00 30.00 ? 217 LYS   A HZ3  1 
ATOM   3279  N  N    . LYS   A 1 219 ? 4.676   36.569  12.551  1.00 23.62 ? 218 LYS   A N    1 
ATOM   3280  C  CA   . LYS   A 1 219 ? 4.189   37.923  12.321  1.00 26.24 ? 218 LYS   A CA   1 
ATOM   3281  C  C    . LYS   A 1 219 ? 3.155   37.978  11.211  1.00 26.25 ? 218 LYS   A C    1 
ATOM   3282  O  O    . LYS   A 1 219 ? 2.272   38.841  11.239  1.00 32.70 ? 218 LYS   A O    1 
ATOM   3283  C  CB   . LYS   A 1 219 ? 5.370   38.844  11.997  1.00 26.18 ? 218 LYS   A CB   1 
ATOM   3284  C  CG   . LYS   A 1 219 ? 6.077   39.362  13.233  1.00 38.15 ? 218 LYS   A CG   1 
ATOM   3285  C  CD   . LYS   A 1 219 ? 7.100   40.452  12.905  1.00 48.63 ? 218 LYS   A CD   1 
ATOM   3286  C  CE   . LYS   A 1 219 ? 8.240   40.477  13.934  1.00 47.55 ? 218 LYS   A CE   1 
ATOM   3287  N  NZ   . LYS   A 1 219 ? 9.556   40.788  13.292  1.00 57.38 ? 218 LYS   A NZ   1 
ATOM   3288  H  H    . LYS   A 1 219 ? 5.439   36.395  12.194  1.00 28.34 ? 218 LYS   A H    1 
ATOM   3289  H  HA   . LYS   A 1 219 ? 3.764   38.249  13.129  1.00 31.49 ? 218 LYS   A HA   1 
ATOM   3290  H  HB2  . LYS   A 1 219 ? 6.017   38.352  11.468  1.00 31.42 ? 218 LYS   A HB2  1 
ATOM   3291  H  HB3  . LYS   A 1 219 ? 5.045   39.609  11.497  1.00 31.42 ? 218 LYS   A HB3  1 
ATOM   3292  H  HG2  . LYS   A 1 219 ? 5.421   39.739  13.841  1.00 45.78 ? 218 LYS   A HG2  1 
ATOM   3293  H  HG3  . LYS   A 1 219 ? 6.545   38.629  13.663  1.00 45.78 ? 218 LYS   A HG3  1 
ATOM   3294  H  HD2  . LYS   A 1 219 ? 7.483   40.281  12.030  1.00 58.35 ? 218 LYS   A HD2  1 
ATOM   3295  H  HD3  . LYS   A 1 219 ? 6.662   41.318  12.912  1.00 58.35 ? 218 LYS   A HD3  1 
ATOM   3296  H  HE2  . LYS   A 1 219 ? 8.057   41.159  14.599  1.00 57.06 ? 218 LYS   A HE2  1 
ATOM   3297  H  HE3  . LYS   A 1 219 ? 8.307   39.608  14.360  1.00 57.06 ? 218 LYS   A HE3  1 
ATOM   3298  H  HZ1  . LYS   A 1 219 ? 10.221  40.603  13.854  1.00 68.85 ? 218 LYS   A HZ1  1 
ATOM   3299  H  HZ2  . LYS   A 1 219 ? 9.658   40.300  12.554  1.00 68.85 ? 218 LYS   A HZ2  1 
ATOM   3300  H  HZ3  . LYS   A 1 219 ? 9.593   41.650  13.075  1.00 68.85 ? 218 LYS   A HZ3  1 
ATOM   3301  N  N    . GLY   A 1 220 ? 3.233   37.081  10.233  1.00 26.00 ? 219 GLY   A N    1 
ATOM   3302  C  CA   . GLY   A 1 220 ? 2.338   37.105  9.104   1.00 30.57 ? 219 GLY   A CA   1 
ATOM   3303  C  C    . GLY   A 1 220 ? 3.060   37.092  7.769   1.00 27.07 ? 219 GLY   A C    1 
ATOM   3304  O  O    . GLY   A 1 220 ? 4.015   37.850  7.553   1.00 32.44 ? 219 GLY   A O    1 
ATOM   3305  H  H    . GLY   A 1 220 ? 3.809   36.443  10.207  1.00 31.20 ? 219 GLY   A H    1 
ATOM   3306  H  HA2  . GLY   A 1 220 ? 1.759   36.327  9.142   1.00 36.69 ? 219 GLY   A HA2  1 
ATOM   3307  H  HA3  . GLY   A 1 220 ? 1.794   37.906  9.146   1.00 36.69 ? 219 GLY   A HA3  1 
ATOM   3308  N  N    . VAL   A 1 221 ? 2.637   36.211  6.886   1.00 24.78 ? 220 VAL   A N    1 
ATOM   3309  C  CA   . VAL   A 1 221 ? 3.125   36.165  5.515   1.00 30.70 ? 220 VAL   A CA   1 
ATOM   3310  C  C    . VAL   A 1 221 ? 1.962   36.428  4.575   1.00 36.33 ? 220 VAL   A C    1 
ATOM   3311  O  O    . VAL   A 1 221 ? 0.821   36.052  4.854   1.00 32.22 ? 220 VAL   A O    1 
ATOM   3312  C  CB   . VAL   A 1 221 ? 3.799   34.825  5.174   1.00 32.39 ? 220 VAL   A CB   1 
ATOM   3313  C  CG1  . VAL   A 1 221 ? 5.017   34.620  6.068   1.00 30.09 ? 220 VAL   A CG1  1 
ATOM   3314  C  CG2  . VAL   A 1 221 ? 2.797   33.663  5.296   1.00 31.33 ? 220 VAL   A CG2  1 
ATOM   3315  H  H    . VAL   A 1 221 ? 2.050   35.607  7.058   1.00 29.74 ? 220 VAL   A H    1 
ATOM   3316  H  HA   . VAL   A 1 221 ? 3.783   36.868  5.398   1.00 36.84 ? 220 VAL   A HA   1 
ATOM   3317  H  HB   . VAL   A 1 221 ? 4.103   34.837  4.253   1.00 38.87 ? 220 VAL   A HB   1 
ATOM   3318  H  HG11 . VAL   A 1 221 ? 5.635   34.017  5.625   1.00 36.11 ? 220 VAL   A HG11 1 
ATOM   3319  H  HG12 . VAL   A 1 221 ? 5.443   35.477  6.221   1.00 36.11 ? 220 VAL   A HG12 1 
ATOM   3320  H  HG13 . VAL   A 1 221 ? 4.728   34.238  6.911   1.00 36.11 ? 220 VAL   A HG13 1 
ATOM   3321  H  HG21 . VAL   A 1 221 ? 3.275   32.859  5.550   1.00 37.59 ? 220 VAL   A HG21 1 
ATOM   3322  H  HG22 . VAL   A 1 221 ? 2.138   33.884  5.974   1.00 37.59 ? 220 VAL   A HG22 1 
ATOM   3323  H  HG23 . VAL   A 1 221 ? 2.359   33.533  4.440   1.00 37.59 ? 220 VAL   A HG23 1 
ATOM   3324  N  N    . GLN   A 1 222 ? 2.241   37.081  3.450   1.00 33.50 ? 221 GLN   A N    1 
ATOM   3325  C  CA   . GLN   A 1 222 ? 1.224   37.382  2.486   1.00 39.19 ? 221 GLN   A CA   1 
ATOM   3326  C  C    . GLN   A 1 222 ? 1.064   36.264  1.511   1.00 37.59 ? 221 GLN   A C    1 
ATOM   3327  O  O    . GLN   A 1 222 ? 2.022   35.749  1.028   1.00 39.26 ? 221 GLN   A O    1 
ATOM   3328  C  CB   . GLN   A 1 222 ? 1.568   38.644  1.714   1.00 46.09 ? 221 GLN   A CB   1 
ATOM   3329  C  CG   . GLN   A 1 222 ? 0.811   39.814  2.267   1.00 50.93 ? 221 GLN   A CG   1 
ATOM   3330  C  CD   . GLN   A 1 222 ? 1.344   40.174  3.605   1.00 53.69 ? 221 GLN   A CD   1 
ATOM   3331  O  OE1  . GLN   A 1 222 ? 0.628   40.275  4.574   1.00 50.84 ? 221 GLN   A OE1  1 
ATOM   3332  N  NE2  . GLN   A 1 222 ? 2.638   40.337  3.666   1.00 55.48 ? 221 GLN   A NE2  1 
ATOM   3333  H  H    . GLN   A 1 222 ? 3.015   37.356  3.192   1.00 40.20 ? 221 GLN   A H    1 
ATOM   3334  H  HA   . GLN   A 1 222 ? 0.408   37.567  2.993   1.00 47.02 ? 221 GLN   A HA   1 
ATOM   3335  H  HB2  . GLN   A 1 222 ? 2.517   38.825  1.795   1.00 55.31 ? 221 GLN   A HB2  1 
ATOM   3336  H  HB3  . GLN   A 1 222 ? 1.322   38.531  0.783   1.00 55.31 ? 221 GLN   A HB3  1 
ATOM   3337  H  HG2  . GLN   A 1 222 ? 0.915   40.577  1.677   1.00 61.12 ? 221 GLN   A HG2  1 
ATOM   3338  H  HG3  . GLN   A 1 222 ? -0.126  39.580  2.360   1.00 61.12 ? 221 GLN   A HG3  1 
ATOM   3339  H  HE21 . GLN   A 1 222 ? 3.121   40.208  2.966   1.00 66.58 ? 221 GLN   A HE21 1 
ATOM   3340  H  HE22 . GLN   A 1 222 ? 3.007   40.574  4.405   1.00 66.58 ? 221 GLN   A HE22 1 
ATOM   3341  N  N    . ILE   A 1 223 ? -0.155  35.846  1.254   1.00 41.91 ? 222 ILE   A N    1 
ATOM   3342  C  CA   . ILE   A 1 223 ? -0.414  34.781  0.342   1.00 43.16 ? 222 ILE   A CA   1 
ATOM   3343  C  C    . ILE   A 1 223 ? -1.602  35.196  -0.526  1.00 53.80 ? 222 ILE   A C    1 
ATOM   3344  O  O    . ILE   A 1 223 ? -2.354  36.079  -0.167  1.00 52.28 ? 222 ILE   A O    1 
ATOM   3345  C  CB   . ILE   A 1 223 ? -0.743  33.482  1.098   1.00 48.76 ? 222 ILE   A CB   1 
ATOM   3346  C  CG1  . ILE   A 1 223 ? -1.840  33.731  2.110   1.00 49.36 ? 222 ILE   A CG1  1 
ATOM   3347  C  CG2  . ILE   A 1 223 ? 0.467   32.951  1.833   1.00 44.22 ? 222 ILE   A CG2  1 
ATOM   3348  C  CD1  . ILE   A 1 223 ? -2.734  32.541  2.320   1.00 48.22 ? 222 ILE   A CD1  1 
ATOM   3349  H  H    . ILE   A 1 223 ? -0.889  36.157  1.578   1.00 50.30 ? 222 ILE   A H    1 
ATOM   3350  H  HA   . ILE   A 1 223 ? 0.367   34.631  -0.231  1.00 51.79 ? 222 ILE   A HA   1 
ATOM   3351  H  HB   . ILE   A 1 223 ? -1.056  32.805  0.483   1.00 58.52 ? 222 ILE   A HB   1 
ATOM   3352  H  HG12 . ILE   A 1 223 ? -1.436  33.956  2.963   1.00 59.23 ? 222 ILE   A HG12 1 
ATOM   3353  H  HG13 . ILE   A 1 223 ? -2.391  34.468  1.801   1.00 59.23 ? 222 ILE   A HG13 1 
ATOM   3354  H  HG21 . ILE   A 1 223 ? 0.306   32.037  2.076   1.00 53.06 ? 222 ILE   A HG21 1 
ATOM   3355  H  HG22 . ILE   A 1 223 ? 1.233   33.008  1.257   1.00 53.06 ? 222 ILE   A HG22 1 
ATOM   3356  H  HG23 . ILE   A 1 223 ? 0.610   33.480  2.622   1.00 53.06 ? 222 ILE   A HG23 1 
ATOM   3357  H  HD11 . ILE   A 1 223 ? -3.570  32.839  2.686   1.00 57.87 ? 222 ILE   A HD11 1 
ATOM   3358  H  HD12 . ILE   A 1 223 ? -2.882  32.109  1.475   1.00 57.87 ? 222 ILE   A HD12 1 
ATOM   3359  H  HD13 . ILE   A 1 223 ? -2.308  31.933  2.929   1.00 57.87 ? 222 ILE   A HD13 1 
ATOM   3360  N  N    . PRO   A 1 224 ? -1.750  34.571  -1.681  1.00 49.93 ? 223 PRO   A N    1 
ATOM   3361  C  CA   . PRO   A 1 224 ? -2.875  34.934  -2.533  1.00 65.74 ? 223 PRO   A CA   1 
ATOM   3362  C  C    . PRO   A 1 224 ? -4.193  34.360  -2.050  1.00 68.92 ? 223 PRO   A C    1 
ATOM   3363  O  O    . PRO   A 1 224 ? -4.267  33.181  -1.774  1.00 61.05 ? 223 PRO   A O    1 
ATOM   3364  C  CB   . PRO   A 1 224 ? -2.537  34.305  -3.875  1.00 61.00 ? 223 PRO   A CB   1 
ATOM   3365  C  CG   . PRO   A 1 224 ? -1.470  33.322  -3.625  1.00 61.57 ? 223 PRO   A CG   1 
ATOM   3366  C  CD   . PRO   A 1 224 ? -0.785  33.707  -2.367  1.00 60.95 ? 223 PRO   A CD   1 
ATOM   3367  H  HA   . PRO   A 1 224 ? -2.915  35.907  -2.635  1.00 78.88 ? 223 PRO   A HA   1 
ATOM   3368  H  HB2  . PRO   A 1 224 ? -3.324  33.867  -4.235  1.00 73.20 ? 223 PRO   A HB2  1 
ATOM   3369  H  HB3  . PRO   A 1 224 ? -2.225  34.994  -4.481  1.00 73.20 ? 223 PRO   A HB3  1 
ATOM   3370  H  HG2  . PRO   A 1 224 ? -1.864  32.440  -3.537  1.00 73.89 ? 223 PRO   A HG2  1 
ATOM   3371  H  HG3  . PRO   A 1 224 ? -0.844  33.336  -4.366  1.00 73.89 ? 223 PRO   A HG3  1 
ATOM   3372  H  HD2  . PRO   A 1 224 ? -0.589  32.907  -1.862  1.00 73.14 ? 223 PRO   A HD2  1 
ATOM   3373  H  HD3  . PRO   A 1 224 ? 0.023   34.203  -2.567  1.00 73.14 ? 223 PRO   A HD3  1 
ATOM   3374  N  N    . LYS   A 1 229 ? -6.602  39.349  -4.807  1.00 82.56 ? 228 LYS   A N    1 
ATOM   3375  C  CA   . LYS   A 1 229 ? -6.465  39.996  -3.498  1.00 77.64 ? 228 LYS   A CA   1 
ATOM   3376  C  C    . LYS   A 1 229 ? -5.440  39.239  -2.681  1.00 74.63 ? 228 LYS   A C    1 
ATOM   3377  O  O    . LYS   A 1 229 ? -5.190  38.090  -2.967  1.00 76.85 ? 228 LYS   A O    1 
ATOM   3378  C  CB   . LYS   A 1 229 ? -7.788  40.066  -2.760  1.00 73.75 ? 228 LYS   A CB   1 
ATOM   3379  H  H    . LYS   A 1 229 ? -7.163  38.697  -4.819  1.00 99.07 ? 228 LYS   A H    1 
ATOM   3380  H  HA   . LYS   A 1 229 ? -6.139  40.911  -3.625  1.00 93.17 ? 228 LYS   A HA   1 
ATOM   3381  N  N    . GLN   A 1 230 ? -4.819  39.897  -1.712  1.00 66.99 ? 229 GLN   A N    1 
ATOM   3382  C  CA   . GLN   A 1 230 ? -3.810  39.232  -0.892  1.00 68.19 ? 229 GLN   A CA   1 
ATOM   3383  C  C    . GLN   A 1 230 ? -4.196  39.178  0.586   1.00 64.80 ? 229 GLN   A C    1 
ATOM   3384  O  O    . GLN   A 1 230 ? -4.667  40.146  1.157   1.00 61.98 ? 229 GLN   A O    1 
ATOM   3385  C  CB   . GLN   A 1 230 ? -2.410  39.864  -1.049  1.00 62.22 ? 229 GLN   A CB   1 
ATOM   3386  C  CG   . GLN   A 1 230 ? -1.693  39.489  -2.335  1.00 68.44 ? 229 GLN   A CG   1 
ATOM   3387  C  CD   . GLN   A 1 230 ? -0.205  39.164  -2.164  1.00 68.54 ? 229 GLN   A CD   1 
ATOM   3388  O  OE1  . GLN   A 1 230 ? 0.211   38.027  -2.322  1.00 74.90 ? 229 GLN   A OE1  1 
ATOM   3389  N  NE2  . GLN   A 1 230 ? 0.600   40.184  -1.883  1.00 60.55 ? 229 GLN   A NE2  1 
ATOM   3390  H  H    . GLN   A 1 230 ? -4.959  40.721  -1.508  1.00 80.38 ? 229 GLN   A H    1 
ATOM   3391  H  HA   . GLN   A 1 230 ? -3.741  38.323  -1.249  1.00 81.82 ? 229 GLN   A HA   1 
ATOM   3392  H  HB2  . GLN   A 1 230 ? -2.499  40.830  -1.034  1.00 74.67 ? 229 GLN   A HB2  1 
ATOM   3393  H  HB3  . GLN   A 1 230 ? -1.854  39.575  -0.309  1.00 74.67 ? 229 GLN   A HB3  1 
ATOM   3394  H  HG2  . GLN   A 1 230 ? -2.124  38.707  -2.715  1.00 82.13 ? 229 GLN   A HG2  1 
ATOM   3395  H  HG3  . GLN   A 1 230 ? -1.761  40.232  -2.956  1.00 82.13 ? 229 GLN   A HG3  1 
ATOM   3396  H  HE21 . GLN   A 1 230 ? 0.285   40.983  -1.842  1.00 72.66 ? 229 GLN   A HE21 1 
ATOM   3397  H  HE22 . GLN   A 1 230 ? 1.438   40.044  -1.742  1.00 72.66 ? 229 GLN   A HE22 1 
ATOM   3398  N  N    . ALA   A 1 231 ? -3.952  38.045  1.231   1.00 49.30 ? 230 ALA   A N    1 
ATOM   3399  C  CA   . ALA   A 1 231 ? -4.295  37.946  2.623   1.00 49.32 ? 230 ALA   A CA   1 
ATOM   3400  C  C    . ALA   A 1 231 ? -3.060  37.655  3.442   1.00 38.65 ? 230 ALA   A C    1 
ATOM   3401  O  O    . ALA   A 1 231 ? -2.034  37.354  2.897   1.00 43.54 ? 230 ALA   A O    1 
ATOM   3402  C  CB   . ALA   A 1 231 ? -5.325  36.874  2.808   1.00 52.08 ? 230 ALA   A CB   1 
ATOM   3403  H  H    . ALA   A 1 231 ? -3.590  37.331  0.918   1.00 59.16 ? 230 ALA   A H    1 
ATOM   3404  H  HA   . ALA   A 1 231 ? -4.675  38.797  2.926   1.00 59.18 ? 230 ALA   A HA   1 
ATOM   3405  H  HB1  . ALA   A 1 231 ? -5.656  36.911  3.709   1.00 62.50 ? 230 ALA   A HB1  1 
ATOM   3406  H  HB2  . ALA   A 1 231 ? -6.044  37.020  2.189   1.00 62.50 ? 230 ALA   A HB2  1 
ATOM   3407  H  HB3  . ALA   A 1 231 ? -4.919  36.020  2.643   1.00 62.50 ? 230 ALA   A HB3  1 
ATOM   3408  N  N    . THR   A 1 232 ? -3.189  37.765  4.751   1.00 36.03 ? 231 THR   A N    1 
ATOM   3409  C  CA   . THR   A 1 232 ? -2.105  37.526  5.658   1.00 32.46 ? 231 THR   A CA   1 
ATOM   3410  C  C    . THR   A 1 232 ? -2.353  36.230  6.466   1.00 37.31 ? 231 THR   A C    1 
ATOM   3411  O  O    . THR   A 1 232 ? -3.360  36.121  7.094   1.00 33.44 ? 231 THR   A O    1 
ATOM   3412  C  CB   . THR   A 1 232 ? -1.974  38.650  6.662   1.00 35.80 ? 231 THR   A CB   1 
ATOM   3413  O  OG1  . THR   A 1 232 ? -1.859  39.901  5.979   1.00 45.08 ? 231 THR   A OG1  1 
ATOM   3414  C  CG2  . THR   A 1 232 ? -0.795  38.439  7.487   1.00 34.05 ? 231 THR   A CG2  1 
ATOM   3415  H  H    . THR   A 1 232 ? -3.922  37.983  5.143   1.00 43.23 ? 231 THR   A H    1 
ATOM   3416  H  HA   . THR   A 1 232 ? -1.278  37.520  5.134   1.00 38.95 ? 231 THR   A HA   1 
ATOM   3417  H  HB   . THR   A 1 232 ? -2.747  38.665  7.242   1.00 42.96 ? 231 THR   A HB   1 
ATOM   3418  H  HG1  . THR   A 1 232 ? -1.158  39.925  5.553   1.00 54.10 ? 231 THR   A HG1  1 
ATOM   3419  H  HG21 . THR   A 1 232 ? -0.437  39.284  7.769   1.00 40.86 ? 231 THR   A HG21 1 
ATOM   3420  H  HG22 . THR   A 1 232 ? -1.027  37.924  8.263   1.00 40.86 ? 231 THR   A HG22 1 
ATOM   3421  H  HG23 . THR   A 1 232 ? -0.125  37.966  6.987   1.00 40.86 ? 231 THR   A HG23 1 
ATOM   3422  N  N    . LYS   A 1 233 ? -1.448  35.269  6.390   1.00 30.05 ? 232 LYS   A N    1 
ATOM   3423  C  CA   . LYS   A 1 233 ? -1.521  34.020  7.137   1.00 29.72 ? 232 LYS   A CA   1 
ATOM   3424  C  C    . LYS   A 1 233 ? -0.527  34.119  8.283   1.00 26.46 ? 232 LYS   A C    1 
ATOM   3425  O  O    . LYS   A 1 233 ? 0.628   34.514  8.074   1.00 25.91 ? 232 LYS   A O    1 
ATOM   3426  C  CB   . LYS   A 1 233 ? -1.210  32.829  6.223   1.00 27.19 ? 232 LYS   A CB   1 
ATOM   3427  C  CG   . LYS   A 1 233 ? -0.891  31.531  6.953   1.00 27.64 ? 232 LYS   A CG   1 
ATOM   3428  C  CD   . LYS   A 1 233 ? -0.478  30.407  5.991   1.00 32.87 ? 232 LYS   A CD   1 
ATOM   3429  C  CE   . LYS   A 1 233 ? -1.679  29.729  5.377   1.00 36.47 ? 232 LYS   A CE   1 
ATOM   3430  N  NZ   . LYS   A 1 233 ? -1.228  28.784  4.312   1.00 41.15 ? 232 LYS   A NZ   1 
ATOM   3431  H  H    . LYS   A 1 233 ? -0.741  35.333  5.905   1.00 36.06 ? 232 LYS   A H    1 
ATOM   3432  H  HA   . LYS   A 1 233 ? -2.407  33.875  7.505   1.00 35.66 ? 232 LYS   A HA   1 
ATOM   3433  H  HB2  . LYS   A 1 233 ? -1.982  32.665  5.659   1.00 32.63 ? 232 LYS   A HB2  1 
ATOM   3434  H  HB3  . LYS   A 1 233 ? -0.441  33.053  5.676   1.00 32.63 ? 232 LYS   A HB3  1 
ATOM   3435  H  HG2  . LYS   A 1 233 ? -0.158  31.684  7.569   1.00 33.17 ? 232 LYS   A HG2  1 
ATOM   3436  H  HG3  . LYS   A 1 233 ? -1.677  31.237  7.439   1.00 33.17 ? 232 LYS   A HG3  1 
ATOM   3437  H  HD2  . LYS   A 1 233 ? 0.060   30.780  5.275   1.00 39.44 ? 232 LYS   A HD2  1 
ATOM   3438  H  HD3  . LYS   A 1 233 ? 0.032   29.741  6.477   1.00 39.44 ? 232 LYS   A HD3  1 
ATOM   3439  H  HE2  . LYS   A 1 233 ? -2.158  29.230  6.057   1.00 43.77 ? 232 LYS   A HE2  1 
ATOM   3440  H  HE3  . LYS   A 1 233 ? -2.264  30.394  4.979   1.00 43.77 ? 232 LYS   A HE3  1 
ATOM   3441  H  HZ1  . LYS   A 1 233 ? -1.360  29.145  3.509   1.00 49.38 ? 232 LYS   A HZ1  1 
ATOM   3442  H  HZ2  . LYS   A 1 233 ? -0.362  28.607  4.409   1.00 49.38 ? 232 LYS   A HZ2  1 
ATOM   3443  H  HZ3  . LYS   A 1 233 ? -1.687  28.024  4.365   1.00 49.38 ? 232 LYS   A HZ3  1 
ATOM   3444  N  N    . TYR   A 1 234 ? -0.959  33.796  9.500   1.00 21.70 ? 233 TYR   A N    1 
ATOM   3445  C  CA   . TYR   A 1 234 ? -0.000  33.781  10.582  1.00 23.76 ? 233 TYR   A CA   1 
ATOM   3446  C  C    . TYR   A 1 234 ? -0.257  32.620  11.530  1.00 20.71 ? 233 TYR   A C    1 
ATOM   3447  O  O    . TYR   A 1 234 ? -1.324  32.019  11.547  1.00 19.68 ? 233 TYR   A O    1 
ATOM   3448  C  CB   . TYR   A 1 234 ? 0.024   35.100  11.345  1.00 23.58 ? 233 TYR   A CB   1 
ATOM   3449  C  CG   . TYR   A 1 234 ? -1.220  35.428  12.088  1.00 23.46 ? 233 TYR   A CG   1 
ATOM   3450  C  CD1  . TYR   A 1 234 ? -2.285  36.061  11.468  1.00 28.60 ? 233 TYR   A CD1  1 
ATOM   3451  C  CD2  . TYR   A 1 234 ? -1.322  35.126  13.434  1.00 27.20 ? 233 TYR   A CD2  1 
ATOM   3452  C  CE1  . TYR   A 1 234 ? -3.431  36.382  12.194  1.00 30.68 ? 233 TYR   A CE1  1 
ATOM   3453  C  CE2  . TYR   A 1 234 ? -2.443  35.443  14.149  1.00 31.90 ? 233 TYR   A CE2  1 
ATOM   3454  C  CZ   . TYR   A 1 234 ? -3.493  36.066  13.522  1.00 32.02 ? 233 TYR   A CZ   1 
ATOM   3455  O  OH   . TYR   A 1 234 ? -4.615  36.346  14.251  1.00 40.51 ? 233 TYR   A OH   1 
ATOM   3456  H  H    . TYR   A 1 234 ? -1.769  33.592  9.707   1.00 26.04 ? 233 TYR   A H    1 
ATOM   3457  H  HA   . TYR   A 1 234 ? 0.877   33.635  10.196  1.00 28.51 ? 233 TYR   A HA   1 
ATOM   3458  H  HB2  . TYR   A 1 234 ? 0.747   35.065  11.991  1.00 28.29 ? 233 TYR   A HB2  1 
ATOM   3459  H  HB3  . TYR   A 1 234 ? 0.180   35.817  10.711  1.00 28.29 ? 233 TYR   A HB3  1 
ATOM   3460  H  HD1  . TYR   A 1 234 ? -2.235  36.274  10.564  1.00 34.32 ? 233 TYR   A HD1  1 
ATOM   3461  H  HD2  . TYR   A 1 234 ? -0.615  34.698  13.860  1.00 32.64 ? 233 TYR   A HD2  1 
ATOM   3462  H  HE1  . TYR   A 1 234 ? -4.147  36.806  11.778  1.00 36.82 ? 233 TYR   A HE1  1 
ATOM   3463  H  HE2  . TYR   A 1 234 ? -2.493  35.239  15.055  1.00 38.29 ? 233 TYR   A HE2  1 
ATOM   3464  H  HH   . TYR   A 1 234 ? -4.945  35.636  14.556  1.00 48.61 ? 233 TYR   A HH   1 
ATOM   3465  N  N    . LEU   A 1 235 ? 0.785   32.299  12.276  1.00 20.36 ? 234 LEU   A N    1 
ATOM   3466  C  CA   . LEU   A 1 235 ? 0.789   31.164  13.183  1.00 19.71 ? 234 LEU   A CA   1 
ATOM   3467  C  C    . LEU   A 1 235 ? 0.115   31.537  14.497  1.00 19.47 ? 234 LEU   A C    1 
ATOM   3468  O  O    . LEU   A 1 235 ? 0.589   32.415  15.230  1.00 23.39 ? 234 LEU   A O    1 
ATOM   3469  C  CB   . LEU   A 1 235 ? 2.232   30.730  13.426  1.00 23.99 ? 234 LEU   A CB   1 
ATOM   3470  C  CG   . LEU   A 1 235 ? 2.481   29.522  14.324  1.00 18.18 ? 234 LEU   A CG   1 
ATOM   3471  C  CD1  . LEU   A 1 235 ? 1.794   28.266  13.707  1.00 19.01 ? 234 LEU   A CD1  1 
ATOM   3472  C  CD2  . LEU   A 1 235 ? 4.003   29.332  14.528  1.00 20.82 ? 234 LEU   A CD2  1 
ATOM   3473  H  H    . LEU   A 1 235 ? 1.525   32.736  12.277  1.00 24.44 ? 234 LEU   A H    1 
ATOM   3474  H  HA   . LEU   A 1 235 ? 0.289   30.430  12.794  1.00 23.66 ? 234 LEU   A HA   1 
ATOM   3475  H  HB2  . LEU   A 1 235 ? 2.625   30.521  12.565  1.00 28.79 ? 234 LEU   A HB2  1 
ATOM   3476  H  HB3  . LEU   A 1 235 ? 2.700   31.477  13.831  1.00 28.79 ? 234 LEU   A HB3  1 
ATOM   3477  H  HG   . LEU   A 1 235 ? 2.094   29.654  15.203  1.00 21.81 ? 234 LEU   A HG   1 
ATOM   3478  H  HD11 . LEU   A 1 235 ? 2.128   27.472  14.153  1.00 22.81 ? 234 LEU   A HD11 1 
ATOM   3479  H  HD12 . LEU   A 1 235 ? 0.835   28.337  13.833  1.00 22.81 ? 234 LEU   A HD12 1 
ATOM   3480  H  HD13 . LEU   A 1 235 ? 2.001   28.226  12.760  1.00 22.81 ? 234 LEU   A HD13 1 
ATOM   3481  H  HD21 . LEU   A 1 235 ? 4.197   28.384  14.590  1.00 24.98 ? 234 LEU   A HD21 1 
ATOM   3482  H  HD22 . LEU   A 1 235 ? 4.474   29.718  13.773  1.00 24.98 ? 234 LEU   A HD22 1 
ATOM   3483  H  HD23 . LEU   A 1 235 ? 4.270   29.779  15.347  1.00 24.98 ? 234 LEU   A HD23 1 
ATOM   3484  N  N    . VAL   A 1 236 ? -0.969  30.851  14.823  1.00 21.42 ? 235 VAL   A N    1 
ATOM   3485  C  CA   . VAL   A 1 236 ? -1.677  31.096  16.082  1.00 22.67 ? 235 VAL   A CA   1 
ATOM   3486  C  C    . VAL   A 1 236 ? -1.122  30.242  17.213  1.00 19.39 ? 235 VAL   A C    1 
ATOM   3487  O  O    . VAL   A 1 236 ? -0.898  30.736  18.323  1.00 22.36 ? 235 VAL   A O    1 
ATOM   3488  C  CB   . VAL   A 1 236 ? -3.195  30.852  15.880  1.00 20.39 ? 235 VAL   A CB   1 
ATOM   3489  C  CG1  . VAL   A 1 236 ? -3.925  30.907  17.213  1.00 27.97 ? 235 VAL   A CG1  1 
ATOM   3490  C  CG2  . VAL   A 1 236 ? -3.769  31.849  14.900  1.00 27.26 ? 235 VAL   A CG2  1 
ATOM   3491  H  H    . VAL   A 1 236 ? -1.320  30.236  14.335  1.00 25.70 ? 235 VAL   A H    1 
ATOM   3492  H  HA   . VAL   A 1 236 ? -1.548  32.024  16.332  1.00 27.21 ? 235 VAL   A HA   1 
ATOM   3493  H  HB   . VAL   A 1 236 ? -3.324  29.966  15.507  1.00 24.47 ? 235 VAL   A HB   1 
ATOM   3494  H  HG11 . VAL   A 1 236 ? -4.861  31.107  17.053  1.00 33.56 ? 235 VAL   A HG11 1 
ATOM   3495  H  HG12 . VAL   A 1 236 ? -3.841  30.047  17.655  1.00 33.56 ? 235 VAL   A HG12 1 
ATOM   3496  H  HG13 . VAL   A 1 236 ? -3.528  31.601  17.762  1.00 33.56 ? 235 VAL   A HG13 1 
ATOM   3497  H  HG21 . VAL   A 1 236 ? -4.737  31.833  14.965  1.00 32.71 ? 235 VAL   A HG21 1 
ATOM   3498  H  HG22 . VAL   A 1 236 ? -3.438  32.734  15.120  1.00 32.71 ? 235 VAL   A HG22 1 
ATOM   3499  H  HG23 . VAL   A 1 236 ? -3.493  31.606  14.003  1.00 32.71 ? 235 VAL   A HG23 1 
ATOM   3500  N  N    . GLN   A 1 237 ? -0.899  28.950  16.967  1.00 19.72 ? 236 GLN   A N    1 
ATOM   3501  C  CA   . GLN   A 1 237 ? -0.453  28.011  17.991  1.00 17.69 ? 236 GLN   A CA   1 
ATOM   3502  C  C    . GLN   A 1 237 ? 0.407   26.960  17.307  1.00 18.49 ? 236 GLN   A C    1 
ATOM   3503  O  O    . GLN   A 1 237 ? 0.088   26.528  16.192  1.00 19.17 ? 236 GLN   A O    1 
ATOM   3504  C  CB   . GLN   A 1 237 ? -1.663  27.370  18.711  1.00 24.94 ? 236 GLN   A CB   1 
ATOM   3505  C  CG   . GLN   A 1 237 ? -1.429  26.285  19.787  1.00 32.25 ? 236 GLN   A CG   1 
ATOM   3506  C  CD   . GLN   A 1 237 ? -0.842  26.858  21.048  1.00 38.85 ? 236 GLN   A CD   1 
ATOM   3507  O  OE1  . GLN   A 1 237 ? -1.304  27.886  21.535  1.00 41.19 ? 236 GLN   A OE1  1 
ATOM   3508  N  NE2  . GLN   A 1 237 ? 0.074   26.116  21.673  1.00 44.46 ? 236 GLN   A NE2  1 
ATOM   3509  H  H    . GLN   A 1 237 ? -1.003  28.587  16.194  1.00 23.66 ? 236 GLN   A H    1 
ATOM   3510  H  HA   . GLN   A 1 237 ? 0.086   28.452  18.666  1.00 21.23 ? 236 GLN   A HA   1 
ATOM   3511  H  HB2  . GLN   A 1 237 ? -2.150  28.085  19.149  1.00 29.93 ? 236 GLN   A HB2  1 
ATOM   3512  H  HB3  . GLN   A 1 237 ? -2.219  26.959  18.030  1.00 29.93 ? 236 GLN   A HB3  1 
ATOM   3513  H  HG2  . GLN   A 1 237 ? -2.276  25.868  20.010  1.00 38.71 ? 236 GLN   A HG2  1 
ATOM   3514  H  HG3  . GLN   A 1 237 ? -0.813  25.620  19.442  1.00 38.71 ? 236 GLN   A HG3  1 
ATOM   3515  H  HE21 . GLN   A 1 237 ? 0.301   25.351  21.351  1.00 53.35 ? 236 GLN   A HE21 1 
ATOM   3516  H  HE22 . GLN   A 1 237 ? 0.438   26.402  22.398  1.00 53.35 ? 236 GLN   A HE22 1 
ATOM   3517  N  N    . GLN   A 1 238 ? 1.508   26.584  17.956  1.00 18.46 ? 237 GLN   A N    1 
ATOM   3518  C  CA   . GLN   A 1 238 ? 2.405   25.539  17.455  1.00 18.89 ? 237 GLN   A CA   1 
ATOM   3519  C  C    . GLN   A 1 238 ? 2.750   24.626  18.620  1.00 19.68 ? 237 GLN   A C    1 
ATOM   3520  O  O    . GLN   A 1 238 ? 3.220   25.105  19.657  1.00 23.46 ? 237 GLN   A O    1 
ATOM   3521  C  CB   . GLN   A 1 238 ? 3.686   26.133  16.872  1.00 17.16 ? 237 GLN   A CB   1 
ATOM   3522  C  CG   . GLN   A 1 238 ? 4.576   25.050  16.299  1.00 16.43 ? 237 GLN   A CG   1 
ATOM   3523  C  CD   . GLN   A 1 238 ? 4.064   24.483  14.989  1.00 19.31 ? 237 GLN   A CD   1 
ATOM   3524  O  OE1  . GLN   A 1 238 ? 3.448   25.181  14.183  1.00 20.00 ? 237 GLN   A OE1  1 
ATOM   3525  N  NE2  . GLN   A 1 238 ? 4.274   23.207  14.801  1.00 16.38 ? 237 GLN   A NE2  1 
ATOM   3526  H  H    . GLN   A 1 238 ? 1.763   26.925  18.703  1.00 22.15 ? 237 GLN   A H    1 
ATOM   3527  H  HA   . GLN   A 1 238 ? 1.956   25.031  16.761  1.00 22.67 ? 237 GLN   A HA   1 
ATOM   3528  H  HB2  . GLN   A 1 238 ? 3.459   26.753  16.161  1.00 20.59 ? 237 GLN   A HB2  1 
ATOM   3529  H  HB3  . GLN   A 1 238 ? 4.175   26.595  17.571  1.00 20.59 ? 237 GLN   A HB3  1 
ATOM   3530  H  HG2  . GLN   A 1 238 ? 5.458   25.421  16.138  1.00 19.72 ? 237 GLN   A HG2  1 
ATOM   3531  H  HG3  . GLN   A 1 238 ? 4.634   24.322  16.937  1.00 19.72 ? 237 GLN   A HG3  1 
ATOM   3532  H  HE21 . GLN   A 1 238 ? 4.681   22.745  15.402  1.00 19.66 ? 237 GLN   A HE21 1 
ATOM   3533  H  HE22 . GLN   A 1 238 ? 4.006   22.830  14.076  1.00 19.66 ? 237 GLN   A HE22 1 
ATOM   3534  N  N    . GLU   A 1 239 ? 2.466   23.343  18.479  1.00 15.14 ? 238 GLU   A N    1 
ATOM   3535  C  CA   . GLU   A 1 239 ? 2.809   22.326  19.474  1.00 20.64 ? 238 GLU   A CA   1 
ATOM   3536  C  C    . GLU   A 1 239 ? 3.568   21.225  18.747  1.00 19.36 ? 238 GLU   A C    1 
ATOM   3537  O  O    . GLU   A 1 239 ? 2.974   20.381  18.083  1.00 19.14 ? 238 GLU   A O    1 
ATOM   3538  C  CB   . GLU   A 1 239 ? 1.564   21.784  20.160  1.00 23.08 ? 238 GLU   A CB   1 
ATOM   3539  C  CG   . GLU   A 1 239 ? 0.916   22.796  21.017  1.00 27.89 ? 238 GLU   A CG   1 
ATOM   3540  C  CD   . GLU   A 1 239 ? -0.356  22.289  21.656  1.00 41.83 ? 238 GLU   A CD   1 
ATOM   3541  O  OE1  . GLU   A 1 239 ? -0.548  21.061  21.717  1.00 42.66 ? 238 GLU   A OE1  1 
ATOM   3542  O  OE2  . GLU   A 1 239 ? -1.157  23.130  22.110  1.00 50.97 ? 238 GLU   A OE2  1 
ATOM   3543  H  H    . GLU   A 1 239 ? 2.061   23.020  17.793  1.00 18.17 ? 238 GLU   A H    1 
ATOM   3544  H  HA   . GLU   A 1 239 ? 3.384   22.709  20.155  1.00 24.77 ? 238 GLU   A HA   1 
ATOM   3545  H  HB2  . GLU   A 1 239 ? 0.926   21.505  19.485  1.00 27.70 ? 238 GLU   A HB2  1 
ATOM   3546  H  HB3  . GLU   A 1 239 ? 1.810   21.029  20.716  1.00 27.70 ? 238 GLU   A HB3  1 
ATOM   3547  H  HG2  . GLU   A 1 239 ? 1.528   23.049  21.725  1.00 33.46 ? 238 GLU   A HG2  1 
ATOM   3548  H  HG3  . GLU   A 1 239 ? 0.692   23.571  20.478  1.00 33.46 ? 238 GLU   A HG3  1 
ATOM   3549  N  N    . SER   A 1 240 ? 4.888   21.264  18.820  1.00 17.86 ? 239 SER   A N    1 
ATOM   3550  C  CA   . SER   A 1 240 ? 5.730   20.264  18.189  1.00 16.15 ? 239 SER   A CA   1 
ATOM   3551  C  C    . SER   A 1 240 ? 7.137   20.419  18.761  1.00 15.76 ? 239 SER   A C    1 
ATOM   3552  O  O    . SER   A 1 240 ? 7.456   21.453  19.341  1.00 19.97 ? 239 SER   A O    1 
ATOM   3553  C  CB   . SER   A 1 240 ? 5.757   20.431  16.654  1.00 15.57 ? 239 SER   A CB   1 
ATOM   3554  O  OG   . SER   A 1 240 ? 6.223   21.720  16.326  1.00 18.57 ? 239 SER   A OG   1 
ATOM   3555  H  H    . SER   A 1 240 ? 5.328   21.873  19.238  1.00 21.43 ? 239 SER   A H    1 
ATOM   3556  H  HA   . SER   A 1 240 ? 5.399   19.375  18.393  1.00 19.38 ? 239 SER   A HA   1 
ATOM   3557  H  HB2  . SER   A 1 240 ? 6.352   19.768  16.270  1.00 18.68 ? 239 SER   A HB2  1 
ATOM   3558  H  HB3  . SER   A 1 240 ? 4.860   20.315  16.303  1.00 18.68 ? 239 SER   A HB3  1 
ATOM   3559  H  HG   . SER   A 1 240 ? 7.063   21.730  16.322  1.00 22.29 ? 239 SER   A HG   1 
ATOM   3560  N  N    . PRO   A 1 241 ? 7.984   19.414  18.595  1.00 18.13 ? 240 PRO   A N    1 
ATOM   3561  C  CA   . PRO   A 1 241 ? 9.363   19.538  19.087  1.00 23.11 ? 240 PRO   A CA   1 
ATOM   3562  C  C    . PRO   A 1 241 ? 10.283  20.306  18.151  1.00 20.35 ? 240 PRO   A C    1 
ATOM   3563  O  O    . PRO   A 1 241 ? 11.395  20.665  18.566  1.00 18.65 ? 240 PRO   A O    1 
ATOM   3564  C  CB   . PRO   A 1 241 ? 9.809   18.077  19.237  1.00 25.52 ? 240 PRO   A CB   1 
ATOM   3565  C  CG   . PRO   A 1 241 ? 9.020   17.342  18.283  1.00 24.56 ? 240 PRO   A CG   1 
ATOM   3566  C  CD   . PRO   A 1 241 ? 7.659   18.043  18.194  1.00 21.71 ? 240 PRO   A CD   1 
ATOM   3567  H  HA   . PRO   A 1 241 ? 9.378   19.960  19.960  1.00 27.73 ? 240 PRO   A HA   1 
ATOM   3568  H  HB2  . PRO   A 1 241 ? 10.755  17.999  19.038  1.00 30.63 ? 240 PRO   A HB2  1 
ATOM   3569  H  HB3  . PRO   A 1 241 ? 9.633   17.770  20.140  1.00 30.63 ? 240 PRO   A HB3  1 
ATOM   3570  H  HG2  . PRO   A 1 241 ? 9.464   17.353  17.420  1.00 29.47 ? 240 PRO   A HG2  1 
ATOM   3571  H  HG3  . PRO   A 1 241 ? 8.912   16.428  18.589  1.00 29.47 ? 240 PRO   A HG3  1 
ATOM   3572  H  HD2  . PRO   A 1 241 ? 7.312   18.017  17.289  1.00 26.05 ? 240 PRO   A HD2  1 
ATOM   3573  H  HD3  . PRO   A 1 241 ? 7.020   17.643  18.805  1.00 26.05 ? 240 PRO   A HD3  1 
ATOM   3574  N  N    . PHE   A 1 242 ? 9.846   20.574  16.917  1.00 19.96 ? 241 PHE   A N    1 
ATOM   3575  C  CA   . PHE   A 1 242 ? 10.622  21.332  15.941  1.00 17.27 ? 241 PHE   A CA   1 
ATOM   3576  C  C    . PHE   A 1 242 ? 9.653   21.829  14.881  1.00 14.59 ? 241 PHE   A C    1 
ATOM   3577  O  O    . PHE   A 1 242 ? 8.520   21.326  14.754  1.00 15.76 ? 241 PHE   A O    1 
ATOM   3578  C  CB   . PHE   A 1 242 ? 11.742  20.481  15.305  1.00 17.46 ? 241 PHE   A CB   1 
ATOM   3579  C  CG   . PHE   A 1 242 ? 11.242  19.334  14.507  1.00 16.29 ? 241 PHE   A CG   1 
ATOM   3580  C  CD1  . PHE   A 1 242 ? 10.959  19.486  13.146  1.00 17.71 ? 241 PHE   A CD1  1 
ATOM   3581  C  CD2  . PHE   A 1 242 ? 11.038  18.093  15.102  1.00 17.61 ? 241 PHE   A CD2  1 
ATOM   3582  C  CE1  . PHE   A 1 242 ? 10.450  18.429  12.402  1.00 20.59 ? 241 PHE   A CE1  1 
ATOM   3583  C  CE2  . PHE   A 1 242 ? 10.537  17.033  14.351  1.00 21.66 ? 241 PHE   A CE2  1 
ATOM   3584  C  CZ   . PHE   A 1 242 ? 10.250  17.205  13.004  1.00 21.23 ? 241 PHE   A CZ   1 
ATOM   3585  H  H    . PHE   A 1 242 ? 9.082   20.319  16.616  1.00 23.95 ? 241 PHE   A H    1 
ATOM   3586  H  HA   . PHE   A 1 242 ? 11.042  22.089  16.377  1.00 20.73 ? 241 PHE   A HA   1 
ATOM   3587  H  HB2  . PHE   A 1 242 ? 12.266  21.046  14.715  1.00 20.95 ? 241 PHE   A HB2  1 
ATOM   3588  H  HB3  . PHE   A 1 242 ? 12.305  20.128  16.012  1.00 20.95 ? 241 PHE   A HB3  1 
ATOM   3589  H  HD1  . PHE   A 1 242 ? 11.113  20.305  12.734  1.00 21.25 ? 241 PHE   A HD1  1 
ATOM   3590  H  HD2  . PHE   A 1 242 ? 11.237  17.971  16.002  1.00 21.13 ? 241 PHE   A HD2  1 
ATOM   3591  H  HE1  . PHE   A 1 242 ? 10.247  18.546  11.502  1.00 24.71 ? 241 PHE   A HE1  1 
ATOM   3592  H  HE2  . PHE   A 1 242 ? 10.394  16.206  14.754  1.00 25.99 ? 241 PHE   A HE2  1 
ATOM   3593  H  HZ   . PHE   A 1 242 ? 9.920   16.492  12.506  1.00 25.48 ? 241 PHE   A HZ   1 
ATOM   3594  N  N    . VAL   A 1 243 ? 10.135  22.795  14.067  1.00 17.45 ? 242 VAL   A N    1 
ATOM   3595  C  CA   . VAL   A 1 243 ? 9.477   23.171  12.831  1.00 16.18 ? 242 VAL   A CA   1 
ATOM   3596  C  C    . VAL   A 1 243 ? 10.551  23.272  11.752  1.00 15.70 ? 242 VAL   A C    1 
ATOM   3597  O  O    . VAL   A 1 243 ? 11.707  23.617  12.024  1.00 17.26 ? 242 VAL   A O    1 
ATOM   3598  C  CB   . VAL   A 1 243 ? 8.692   24.504  12.929  1.00 18.62 ? 242 VAL   A CB   1 
ATOM   3599  C  CG1  . VAL   A 1 243 ? 7.546   24.403  13.971  1.00 21.30 ? 242 VAL   A CG1  1 
ATOM   3600  C  CG2  . VAL   A 1 243 ? 9.611   25.603  13.237  1.00 20.65 ? 242 VAL   A CG2  1 
ATOM   3601  H  H    . VAL   A 1 243 ? 10.852  23.242  14.226  1.00 20.94 ? 242 VAL   A H    1 
ATOM   3602  H  HA   . VAL   A 1 243 ? 8.835   22.481  12.597  1.00 19.42 ? 242 VAL   A HA   1 
ATOM   3603  H  HB   . VAL   A 1 243 ? 8.275   24.694  12.074  1.00 22.35 ? 242 VAL   A HB   1 
ATOM   3604  H  HG11 . VAL   A 1 243 ? 6.913   25.121  13.815  1.00 25.56 ? 242 VAL   A HG11 1 
ATOM   3605  H  HG12 . VAL   A 1 243 ? 7.104   23.545  13.872  1.00 25.56 ? 242 VAL   A HG12 1 
ATOM   3606  H  HG13 . VAL   A 1 243 ? 7.921   24.480  14.862  1.00 25.56 ? 242 VAL   A HG13 1 
ATOM   3607  H  HG21 . VAL   A 1 243 ? 9.112   26.326  13.649  1.00 24.77 ? 242 VAL   A HG21 1 
ATOM   3608  H  HG22 . VAL   A 1 243 ? 10.293  25.282  13.848  1.00 24.77 ? 242 VAL   A HG22 1 
ATOM   3609  H  HG23 . VAL   A 1 243 ? 10.022  25.911  12.414  1.00 24.77 ? 242 VAL   A HG23 1 
ATOM   3610  N  N    . MET   A 1 244 ? 10.165  22.932  10.540  1.00 15.11 ? 243 MET   A N    1 
ATOM   3611  C  CA   . MET   A 1 244 ? 11.034  22.989  9.374   1.00 16.50 ? 243 MET   A CA   1 
ATOM   3612  C  C    . MET   A 1 244 ? 10.449  24.035  8.434   1.00 14.57 ? 243 MET   A C    1 
ATOM   3613  O  O    . MET   A 1 244 ? 9.321   23.875  7.957   1.00 16.89 ? 243 MET   A O    1 
ATOM   3614  C  CB   . MET   A 1 244 ? 11.107  21.620  8.721   1.00 17.29 ? 243 MET   A CB   1 
ATOM   3615  C  CG   . MET   A 1 244 ? 11.790  21.642  7.390   1.00 16.86 ? 243 MET   A CG   1 
ATOM   3616  S  SD   . MET   A 1 244 ? 12.095  20.059  6.575   1.00 22.82 ? 243 MET   A SD   1 
ATOM   3617  C  CE   . MET   A 1 244 ? 10.587  19.672  5.701   1.00 33.84 ? 243 MET   A CE   1 
ATOM   3618  H  H    . MET   A 1 244 ? 9.373   22.652  10.356  1.00 18.13 ? 243 MET   A H    1 
ATOM   3619  H  HA   . MET   A 1 244 ? 11.935  23.251  9.621   1.00 19.80 ? 243 MET   A HA   1 
ATOM   3620  H  HB2  . MET   A 1 244 ? 11.602  21.021  9.301   1.00 20.75 ? 243 MET   A HB2  1 
ATOM   3621  H  HB3  . MET   A 1 244 ? 10.206  21.286  8.589   1.00 20.75 ? 243 MET   A HB3  1 
ATOM   3622  H  HG2  . MET   A 1 244 ? 11.243  22.166  6.785   1.00 20.23 ? 243 MET   A HG2  1 
ATOM   3623  H  HG3  . MET   A 1 244 ? 12.655  22.066  7.508   1.00 20.23 ? 243 MET   A HG3  1 
ATOM   3624  H  HE1  . MET   A 1 244 ? 10.788  19.558  4.759   1.00 40.61 ? 243 MET   A HE1  1 
ATOM   3625  H  HE2  . MET   A 1 244 ? 10.214  18.852  6.062   1.00 40.61 ? 243 MET   A HE2  1 
ATOM   3626  H  HE3  . MET   A 1 244 ? 9.958   20.401  5.819   1.00 40.61 ? 243 MET   A HE3  1 
ATOM   3627  N  N    . MET   A 1 245 ? 11.179  25.115  8.235   1.00 14.77 ? 244 MET   A N    1 
ATOM   3628  C  CA   . MET   A 1 245 ? 10.774  26.192  7.353   1.00 15.22 ? 244 MET   A CA   1 
ATOM   3629  C  C    . MET   A 1 245 ? 11.642  26.148  6.106   1.00 17.32 ? 244 MET   A C    1 
ATOM   3630  O  O    . MET   A 1 245 ? 12.882  26.158  6.208   1.00 17.08 ? 244 MET   A O    1 
ATOM   3631  C  CB   . MET   A 1 245 ? 10.873  27.564  8.020   1.00 13.66 ? 244 MET   A CB   1 
ATOM   3632  C  CG   . MET   A 1 245 ? 10.306  27.664  9.401   1.00 17.17 ? 244 MET   A CG   1 
ATOM   3633  S  SD   . MET   A 1 245 ? 8.498   27.724  9.352   1.00 18.86 ? 244 MET   A SD   1 
ATOM   3634  C  CE   . MET   A 1 245 ? 8.114   29.142  8.346   1.00 18.27 ? 244 MET   A CE   1 
ATOM   3635  H  H    . MET   A 1 245 ? 11.939  25.252  8.613   1.00 17.72 ? 244 MET   A H    1 
ATOM   3636  H  HA   . MET   A 1 245 ? 9.842   26.068  7.116   1.00 18.26 ? 244 MET   A HA   1 
ATOM   3637  H  HB2  . MET   A 1 245 ? 11.810  27.807  8.076   1.00 16.39 ? 244 MET   A HB2  1 
ATOM   3638  H  HB3  . MET   A 1 245 ? 10.397  28.205  7.468   1.00 16.39 ? 244 MET   A HB3  1 
ATOM   3639  H  HG2  . MET   A 1 245 ? 10.575  26.888  9.918   1.00 20.60 ? 244 MET   A HG2  1 
ATOM   3640  H  HG3  . MET   A 1 245 ? 10.630  28.473  9.826   1.00 20.60 ? 244 MET   A HG3  1 
ATOM   3641  H  HE1  . MET   A 1 245 ? 7.295   29.547  8.672   1.00 21.92 ? 244 MET   A HE1  1 
ATOM   3642  H  HE2  . MET   A 1 245 ? 8.844   29.777  8.405   1.00 21.92 ? 244 MET   A HE2  1 
ATOM   3643  H  HE3  . MET   A 1 245 ? 7.997   28.855  7.427   1.00 21.92 ? 244 MET   A HE3  1 
ATOM   3644  N  N    . SER   A 1 246 ? 10.987  26.083  4.948   1.00 16.95 ? 245 SER   A N    1 
ATOM   3645  C  CA   . SER   A 1 246 ? 11.681  25.946  3.685   1.00 14.48 ? 245 SER   A CA   1 
ATOM   3646  C  C    . SER   A 1 246 ? 11.236  26.987  2.668   1.00 16.53 ? 245 SER   A C    1 
ATOM   3647  O  O    . SER   A 1 246 ? 10.125  27.518  2.733   1.00 18.52 ? 245 SER   A O    1 
ATOM   3648  C  CB   . SER   A 1 246 ? 11.461  24.564  3.071   1.00 15.30 ? 245 SER   A CB   1 
ATOM   3649  O  OG   . SER   A 1 246 ? 11.890  23.511  3.929   1.00 16.91 ? 245 SER   A OG   1 
ATOM   3650  H  H    . SER   A 1 246 ? 10.131  26.118  4.875   1.00 20.34 ? 245 SER   A H    1 
ATOM   3651  H  HA   . SER   A 1 246 ? 12.623  26.092  3.865   1.00 17.38 ? 245 SER   A HA   1 
ATOM   3652  H  HB2  . SER   A 1 246 ? 10.514  24.451  2.893   1.00 18.36 ? 245 SER   A HB2  1 
ATOM   3653  H  HB3  . SER   A 1 246 ? 11.962  24.511  2.242   1.00 18.36 ? 245 SER   A HB3  1 
ATOM   3654  H  HG   . SER   A 1 246 ? 12.112  22.841  3.473   1.00 20.29 ? 245 SER   A HG   1 
ATOM   3655  N  N    . ALA   A 1 247 ? 12.097  27.200  1.683   1.00 15.98 ? 246 ALA   A N    1 
ATOM   3656  C  CA   . ALA   A 1 247 ? 11.779  28.072  0.550   1.00 16.66 ? 246 ALA   A CA   1 
ATOM   3657  C  C    . ALA   A 1 247 ? 12.799  27.829  -0.555  1.00 20.62 ? 246 ALA   A C    1 
ATOM   3658  O  O    . ALA   A 1 247 ? 13.918  27.373  -0.283  1.00 17.19 ? 246 ALA   A O    1 
ATOM   3659  C  CB   . ALA   A 1 247 ? 11.786  29.547  0.970   1.00 19.04 ? 246 ALA   A CB   1 
ATOM   3660  H  H    . ALA   A 1 247 ? 12.882  26.850  1.643   1.00 19.17 ? 246 ALA   A H    1 
ATOM   3661  H  HA   . ALA   A 1 247 ? 10.901  27.848  0.203   1.00 19.99 ? 246 ALA   A HA   1 
ATOM   3662  H  HB1  . ALA   A 1 247 ? 12.126  30.083  0.236   1.00 22.85 ? 246 ALA   A HB1  1 
ATOM   3663  H  HB2  . ALA   A 1 247 ? 10.880  29.818  1.186   1.00 22.85 ? 246 ALA   A HB2  1 
ATOM   3664  H  HB3  . ALA   A 1 247 ? 12.357  29.651  1.747   1.00 22.85 ? 246 ALA   A HB3  1 
ATOM   3665  N  N    . PRO   A 1 248 ? 12.465  28.152  -1.810  1.00 20.82 ? 247 PRO   A N    1 
ATOM   3666  C  CA   . PRO   A 1 248 ? 13.482  28.041  -2.860  1.00 19.86 ? 247 PRO   A CA   1 
ATOM   3667  C  C    . PRO   A 1 248 ? 14.726  28.796  -2.429  1.00 16.51 ? 247 PRO   A C    1 
ATOM   3668  O  O    . PRO   A 1 248 ? 14.624  29.825  -1.746  1.00 16.72 ? 247 PRO   A O    1 
ATOM   3669  C  CB   . PRO   A 1 248 ? 12.808  28.672  -4.098  1.00 18.07 ? 247 PRO   A CB   1 
ATOM   3670  C  CG   . PRO   A 1 248 ? 11.315  28.498  -3.848  1.00 19.70 ? 247 PRO   A CG   1 
ATOM   3671  C  CD   . PRO   A 1 248 ? 11.173  28.667  -2.323  1.00 22.47 ? 247 PRO   A CD   1 
ATOM   3672  H  HA   . PRO   A 1 248 ? 13.697  27.119  -3.069  1.00 23.83 ? 247 PRO   A HA   1 
ATOM   3673  H  HB2  . PRO   A 1 248 ? 13.045  29.610  -4.163  1.00 21.68 ? 247 PRO   A HB2  1 
ATOM   3674  H  HB3  . PRO   A 1 248 ? 13.085  28.204  -4.901  1.00 21.68 ? 247 PRO   A HB3  1 
ATOM   3675  H  HG2  . PRO   A 1 248 ? 10.814  29.178  -4.324  1.00 23.63 ? 247 PRO   A HG2  1 
ATOM   3676  H  HG3  . PRO   A 1 248 ? 11.029  27.616  -4.132  1.00 23.63 ? 247 PRO   A HG3  1 
ATOM   3677  H  HD2  . PRO   A 1 248 ? 11.054  29.600  -2.087  1.00 26.96 ? 247 PRO   A HD2  1 
ATOM   3678  H  HD3  . PRO   A 1 248 ? 10.432  28.142  -1.984  1.00 26.96 ? 247 PRO   A HD3  1 
ATOM   3679  N  N    . PRO   A 1 249 ? 15.913  28.277  -2.736  1.00 16.44 ? 248 PRO   A N    1 
ATOM   3680  C  CA   . PRO   A 1 249 ? 17.153  28.866  -2.224  1.00 17.64 ? 248 PRO   A CA   1 
ATOM   3681  C  C    . PRO   A 1 249 ? 17.230  30.366  -2.443  1.00 23.30 ? 248 PRO   A C    1 
ATOM   3682  O  O    . PRO   A 1 249 ? 16.942  30.864  -3.534  1.00 21.25 ? 248 PRO   A O    1 
ATOM   3683  C  CB   . PRO   A 1 249 ? 18.242  28.143  -3.039  1.00 22.40 ? 248 PRO   A CB   1 
ATOM   3684  C  CG   . PRO   A 1 249 ? 17.647  26.821  -3.335  1.00 20.03 ? 248 PRO   A CG   1 
ATOM   3685  C  CD   . PRO   A 1 249 ? 16.185  27.105  -3.584  1.00 21.10 ? 248 PRO   A CD   1 
ATOM   3686  H  HA   . PRO   A 1 249 ? 17.235  28.675  -1.276  1.00 21.16 ? 248 PRO   A HA   1 
ATOM   3687  H  HB2  . PRO   A 1 249 ? 18.430  28.634  -3.854  1.00 26.87 ? 248 PRO   A HB2  1 
ATOM   3688  H  HB3  . PRO   A 1 249 ? 19.051  28.054  -2.511  1.00 26.87 ? 248 PRO   A HB3  1 
ATOM   3689  H  HG2  . PRO   A 1 249 ? 18.065  26.438  -4.122  1.00 24.04 ? 248 PRO   A HG2  1 
ATOM   3690  H  HG3  . PRO   A 1 249 ? 17.762  26.228  -2.577  1.00 24.04 ? 248 PRO   A HG3  1 
ATOM   3691  H  HD2  . PRO   A 1 249 ? 16.028  27.312  -4.518  1.00 25.32 ? 248 PRO   A HD2  1 
ATOM   3692  H  HD3  . PRO   A 1 249 ? 15.637  26.351  -3.315  1.00 25.32 ? 248 PRO   A HD3  1 
ATOM   3693  N  N    . ALA   A 1 250 ? 17.673  31.078  -1.410  1.00 19.05 ? 249 ALA   A N    1 
ATOM   3694  C  CA   . ALA   A 1 250 ? 17.839  32.526  -1.496  1.00 24.95 ? 249 ALA   A CA   1 
ATOM   3695  C  C    . ALA   A 1 250 ? 18.867  32.967  -0.465  1.00 20.67 ? 249 ALA   A C    1 
ATOM   3696  O  O    . ALA   A 1 250 ? 19.050  32.313  0.573   1.00 19.26 ? 249 ALA   A O    1 
ATOM   3697  C  CB   . ALA   A 1 250 ? 16.522  33.274  -1.247  1.00 31.92 ? 249 ALA   A CB   1 
ATOM   3698  H  H    . ALA   A 1 250 ? 17.885  30.745  -0.646  1.00 22.86 ? 249 ALA   A H    1 
ATOM   3699  H  HA   . ALA   A 1 250 ? 18.160  32.748  -2.384  1.00 29.94 ? 249 ALA   A HA   1 
ATOM   3700  H  HB1  . ALA   A 1 250 ? 16.609  34.184  -1.572  1.00 38.31 ? 249 ALA   A HB1  1 
ATOM   3701  H  HB2  . ALA   A 1 250 ? 15.807  32.821  -1.720  1.00 38.31 ? 249 ALA   A HB2  1 
ATOM   3702  H  HB3  . ALA   A 1 250 ? 16.337  33.279  -0.294  1.00 38.31 ? 249 ALA   A HB3  1 
ATOM   3703  N  N    . GLN   A 1 251 ? 19.513  34.101  -0.743  1.00 19.91 ? 250 GLN   A N    1 
ATOM   3704  C  CA   . GLN   A 1 251 ? 20.520  34.617  0.167   1.00 17.85 ? 250 GLN   A CA   1 
ATOM   3705  C  C    . GLN   A 1 251 ? 19.864  34.986  1.493   1.00 17.71 ? 250 GLN   A C    1 
ATOM   3706  O  O    . GLN   A 1 251 ? 18.840  35.672  1.517   1.00 18.57 ? 250 GLN   A O    1 
ATOM   3707  C  CB   . GLN   A 1 251 ? 21.215  35.836  -0.444  1.00 21.59 ? 250 GLN   A CB   1 
ATOM   3708  C  CG   . GLN   A 1 251 ? 22.491  36.176  0.273   1.00 25.82 ? 250 GLN   A CG   1 
ATOM   3709  C  CD   . GLN   A 1 251 ? 23.672  35.304  -0.138  1.00 25.58 ? 250 GLN   A CD   1 
ATOM   3710  O  OE1  . GLN   A 1 251 ? 23.516  34.254  -0.765  1.00 26.62 ? 250 GLN   A OE1  1 
ATOM   3711  N  NE2  . GLN   A 1 251 ? 24.861  35.728  0.254   1.00 31.58 ? 250 GLN   A NE2  1 
ATOM   3712  H  H    . GLN   A 1 251 ? 19.384  34.580  -1.445  1.00 23.89 ? 250 GLN   A H    1 
ATOM   3713  H  HA   . GLN   A 1 251 ? 21.199  33.942  0.326   1.00 21.42 ? 250 GLN   A HA   1 
ATOM   3714  H  HB2  . GLN   A 1 251 ? 21.429  35.649  -1.371  1.00 25.91 ? 250 GLN   A HB2  1 
ATOM   3715  H  HB3  . GLN   A 1 251 ? 20.622  36.601  -0.388  1.00 25.91 ? 250 GLN   A HB3  1 
ATOM   3716  H  HG2  . GLN   A 1 251 ? 22.722  37.098  0.079   1.00 30.98 ? 250 GLN   A HG2  1 
ATOM   3717  H  HG3  . GLN   A 1 251 ? 22.355  36.061  1.226   1.00 30.98 ? 250 GLN   A HG3  1 
ATOM   3718  H  HE21 . GLN   A 1 251 ? 24.930  36.454  0.709   1.00 37.90 ? 250 GLN   A HE21 1 
ATOM   3719  H  HE22 . GLN   A 1 251 ? 25.566  35.278  0.052   1.00 37.90 ? 250 GLN   A HE22 1 
ATOM   3720  N  N    . TYR   A 1 252 ? 20.459  34.520  2.579   1.00 17.86 ? 251 TYR   A N    1 
ATOM   3721  C  CA   . TYR   A 1 252 ? 19.851  34.554  3.907   1.00 19.87 ? 251 TYR   A CA   1 
ATOM   3722  C  C    . TYR   A 1 252 ? 20.936  34.748  4.954   1.00 19.83 ? 251 TYR   A C    1 
ATOM   3723  O  O    . TYR   A 1 252 ? 22.048  34.208  4.836   1.00 20.51 ? 251 TYR   A O    1 
ATOM   3724  C  CB   . TYR   A 1 252 ? 19.035  33.256  4.135   1.00 17.71 ? 251 TYR   A CB   1 
ATOM   3725  C  CG   . TYR   A 1 252 ? 18.015  33.353  5.271   1.00 19.53 ? 251 TYR   A CG   1 
ATOM   3726  C  CD1  . TYR   A 1 252 ? 16.775  33.942  5.067   1.00 18.32 ? 251 TYR   A CD1  1 
ATOM   3727  C  CD2  . TYR   A 1 252 ? 18.295  32.831  6.515   1.00 22.20 ? 251 TYR   A CD2  1 
ATOM   3728  C  CE1  . TYR   A 1 252 ? 15.872  34.067  6.065   1.00 22.06 ? 251 TYR   A CE1  1 
ATOM   3729  C  CE2  . TYR   A 1 252 ? 17.368  32.925  7.540   1.00 20.40 ? 251 TYR   A CE2  1 
ATOM   3730  C  CZ   . TYR   A 1 252 ? 16.163  33.540  7.295   1.00 22.02 ? 251 TYR   A CZ   1 
ATOM   3731  O  OH   . TYR   A 1 252 ? 15.221  33.654  8.249   1.00 25.26 ? 251 TYR   A OH   1 
ATOM   3732  H  H    . TYR   A 1 252 ? 21.243  34.166  2.578   1.00 21.43 ? 251 TYR   A H    1 
ATOM   3733  H  HA   . TYR   A 1 252 ? 19.253  35.311  4.003   1.00 23.84 ? 251 TYR   A HA   1 
ATOM   3734  H  HB2  . TYR   A 1 252 ? 18.551  33.046  3.321   1.00 21.25 ? 251 TYR   A HB2  1 
ATOM   3735  H  HB3  . TYR   A 1 252 ? 19.649  32.536  4.351   1.00 21.25 ? 251 TYR   A HB3  1 
ATOM   3736  H  HD1  . TYR   A 1 252 ? 16.559  34.260  4.220   1.00 21.98 ? 251 TYR   A HD1  1 
ATOM   3737  H  HD2  . TYR   A 1 252 ? 19.112  32.414  6.667   1.00 26.64 ? 251 TYR   A HD2  1 
ATOM   3738  H  HE1  . TYR   A 1 252 ? 15.065  34.504  5.918   1.00 26.47 ? 251 TYR   A HE1  1 
ATOM   3739  H  HE2  . TYR   A 1 252 ? 17.558  32.576  8.381   1.00 24.48 ? 251 TYR   A HE2  1 
ATOM   3740  H  HH   . TYR   A 1 252 ? 14.788  34.366  8.142   1.00 30.32 ? 251 TYR   A HH   1 
ATOM   3741  N  N    . GLU   A 1 253 ? 20.610  35.528  5.985   1.00 18.83 ? 252 GLU   A N    1 
ATOM   3742  C  CA   . GLU   A 1 253 ? 21.508  35.780  7.104   1.00 21.28 ? 252 GLU   A CA   1 
ATOM   3743  C  C    . GLU   A 1 253 ? 21.092  34.912  8.289   1.00 21.69 ? 252 GLU   A C    1 
ATOM   3744  O  O    . GLU   A 1 253 ? 19.957  35.012  8.758   1.00 22.27 ? 252 GLU   A O    1 
ATOM   3745  C  CB   . GLU   A 1 253 ? 21.476  37.255  7.520   1.00 19.97 ? 252 GLU   A CB   1 
ATOM   3746  C  CG   . GLU   A 1 253 ? 22.471  37.627  8.607   1.00 23.76 ? 252 GLU   A CG   1 
ATOM   3747  C  CD   . GLU   A 1 253 ? 22.525  39.151  8.875   1.00 33.22 ? 252 GLU   A CD   1 
ATOM   3748  O  OE1  . GLU   A 1 253 ? 21.651  39.899  8.405   1.00 46.06 ? 252 GLU   A OE1  1 
ATOM   3749  O  OE2  . GLU   A 1 253 ? 23.491  39.600  9.499   1.00 43.39 ? 252 GLU   A OE2  1 
ATOM   3750  H  H    . GLU   A 1 253 ? 19.854  35.931  6.057   1.00 22.60 ? 252 GLU   A H    1 
ATOM   3751  H  HA   . GLU   A 1 253 ? 22.410  35.547  6.836   1.00 25.54 ? 252 GLU   A HA   1 
ATOM   3752  H  HB2  . GLU   A 1 253 ? 21.675  37.799  6.742   1.00 23.97 ? 252 GLU   A HB2  1 
ATOM   3753  H  HB3  . GLU   A 1 253 ? 20.589  37.463  7.852   1.00 23.97 ? 252 GLU   A HB3  1 
ATOM   3754  H  HG2  . GLU   A 1 253 ? 22.217  37.186  9.432   1.00 28.51 ? 252 GLU   A HG2  1 
ATOM   3755  H  HG3  . GLU   A 1 253 ? 23.357  37.339  8.336   1.00 28.51 ? 252 GLU   A HG3  1 
ATOM   3756  N  N    . LEU   A 1 254 ? 21.996  34.061  8.757   1.00 16.95 ? 253 LEU   A N    1 
ATOM   3757  C  CA   . LEU   A 1 254 ? 21.745  33.229  9.927   1.00 21.11 ? 253 LEU   A CA   1 
ATOM   3758  C  C    . LEU   A 1 254 ? 22.503  33.818  11.106  1.00 26.69 ? 253 LEU   A C    1 
ATOM   3759  O  O    . LEU   A 1 254 ? 23.697  34.126  10.984  1.00 25.53 ? 253 LEU   A O    1 
ATOM   3760  C  CB   . LEU   A 1 254 ? 22.178  31.782  9.700   1.00 18.01 ? 253 LEU   A CB   1 
ATOM   3761  C  CG   . LEU   A 1 254 ? 21.381  31.004  8.652   1.00 19.54 ? 253 LEU   A CG   1 
ATOM   3762  C  CD1  . LEU   A 1 254 ? 21.998  29.676  8.264   1.00 21.66 ? 253 LEU   A CD1  1 
ATOM   3763  C  CD2  . LEU   A 1 254 ? 19.929  30.818  9.120   1.00 23.14 ? 253 LEU   A CD2  1 
ATOM   3764  H  H    . LEU   A 1 254 ? 22.774  33.946  8.409   1.00 20.34 ? 253 LEU   A H    1 
ATOM   3765  H  HA   . LEU   A 1 254 ? 20.794  33.220  10.120  1.00 25.34 ? 253 LEU   A HA   1 
ATOM   3766  H  HB2  . LEU   A 1 254 ? 23.104  31.785  9.413   1.00 21.61 ? 253 LEU   A HB2  1 
ATOM   3767  H  HB3  . LEU   A 1 254 ? 22.092  31.305  10.540  1.00 21.61 ? 253 LEU   A HB3  1 
ATOM   3768  H  HG   . LEU   A 1 254 ? 21.393  31.534  7.840   1.00 23.45 ? 253 LEU   A HG   1 
ATOM   3769  H  HD11 . LEU   A 1 254 ? 21.578  29.359  7.449   1.00 25.99 ? 253 LEU   A HD11 1 
ATOM   3770  H  HD12 . LEU   A 1 254 ? 22.949  29.800  8.120   1.00 25.99 ? 253 LEU   A HD12 1 
ATOM   3771  H  HD13 . LEU   A 1 254 ? 21.853  29.039  8.981   1.00 25.99 ? 253 LEU   A HD13 1 
ATOM   3772  H  HD21 . LEU   A 1 254 ? 19.496  30.161  8.552   1.00 27.76 ? 253 LEU   A HD21 1 
ATOM   3773  H  HD22 . LEU   A 1 254 ? 19.931  30.511  10.040  1.00 27.76 ? 253 LEU   A HD22 1 
ATOM   3774  H  HD23 . LEU   A 1 254 ? 19.466  31.668  9.055   1.00 27.76 ? 253 LEU   A HD23 1 
ATOM   3775  N  N    . LYS   A 1 255 ? 21.819  33.953  12.244  1.00 25.62 ? 254 LYS   A N    1 
ATOM   3776  C  CA   . LYS   A 1 255 ? 22.388  34.547  13.442  1.00 24.85 ? 254 LYS   A CA   1 
ATOM   3777  C  C    . LYS   A 1 255 ? 22.504  33.495  14.533  1.00 22.31 ? 254 LYS   A C    1 
ATOM   3778  O  O    . LYS   A 1 255 ? 21.563  32.738  14.766  1.00 19.63 ? 254 LYS   A O    1 
ATOM   3779  C  CB   . LYS   A 1 255 ? 21.533  35.714  13.925  1.00 26.75 ? 254 LYS   A CB   1 
ATOM   3780  C  CG   . LYS   A 1 255 ? 21.359  36.826  12.897  1.00 31.80 ? 254 LYS   A CG   1 
ATOM   3781  C  CD   . LYS   A 1 255 ? 22.011  38.132  13.311  1.00 44.32 ? 254 LYS   A CD   1 
ATOM   3782  C  CE   . LYS   A 1 255 ? 23.531  38.019  13.426  1.00 51.82 ? 254 LYS   A CE   1 
ATOM   3783  N  NZ   . LYS   A 1 255 ? 24.221  39.339  13.176  1.00 47.37 ? 254 LYS   A NZ   1 
ATOM   3784  H  H    . LYS   A 1 255 ? 21.004  33.700  12.342  1.00 30.75 ? 254 LYS   A H    1 
ATOM   3785  H  HA   . LYS   A 1 255 ? 23.279  34.877  13.246  1.00 29.82 ? 254 LYS   A HA   1 
ATOM   3786  H  HB2  . LYS   A 1 255 ? 20.651  35.381  14.151  1.00 32.10 ? 254 LYS   A HB2  1 
ATOM   3787  H  HB3  . LYS   A 1 255 ? 21.952  36.102  14.709  1.00 32.10 ? 254 LYS   A HB3  1 
ATOM   3788  H  HG2  . LYS   A 1 255 ? 21.759  36.546  12.059  1.00 38.16 ? 254 LYS   A HG2  1 
ATOM   3789  H  HG3  . LYS   A 1 255 ? 20.411  36.993  12.772  1.00 38.16 ? 254 LYS   A HG3  1 
ATOM   3790  H  HD2  . LYS   A 1 255 ? 21.810  38.811  12.648  1.00 53.18 ? 254 LYS   A HD2  1 
ATOM   3791  H  HD3  . LYS   A 1 255 ? 21.664  38.399  14.176  1.00 53.18 ? 254 LYS   A HD3  1 
ATOM   3792  H  HE2  . LYS   A 1 255 ? 23.761  37.723  14.320  1.00 62.19 ? 254 LYS   A HE2  1 
ATOM   3793  H  HE3  . LYS   A 1 255 ? 23.853  37.381  12.771  1.00 62.19 ? 254 LYS   A HE3  1 
ATOM   3794  H  HZ1  . LYS   A 1 255 ? 23.940  39.689  12.407  1.00 56.84 ? 254 LYS   A HZ1  1 
ATOM   3795  H  HZ2  . LYS   A 1 255 ? 25.102  39.218  13.133  1.00 56.84 ? 254 LYS   A HZ2  1 
ATOM   3796  H  HZ3  . LYS   A 1 255 ? 24.039  39.908  13.836  1.00 56.84 ? 254 LYS   A HZ3  1 
ATOM   3797  N  N    . HIS   A 1 256 ? 23.662  33.465  15.195  1.00 20.91 ? 255 HIS   A N    1 
ATOM   3798  C  CA   . HIS   A 1 256 ? 23.947  32.510  16.253  1.00 22.31 ? 255 HIS   A CA   1 
ATOM   3799  C  C    . HIS   A 1 256 ? 22.840  32.495  17.301  1.00 21.67 ? 255 HIS   A C    1 
ATOM   3800  O  O    . HIS   A 1 256 ? 22.370  33.541  17.750  1.00 23.38 ? 255 HIS   A O    1 
ATOM   3801  C  CB   . HIS   A 1 256 ? 25.316  32.869  16.872  1.00 25.92 ? 255 HIS   A CB   1 
ATOM   3802  C  CG   . HIS   A 1 256 ? 25.650  32.117  18.119  1.00 25.78 ? 255 HIS   A CG   1 
ATOM   3803  N  ND1  . HIS   A 1 256 ? 25.740  32.734  19.346  1.00 33.20 ? 255 HIS   A ND1  1 
ATOM   3804  C  CD2  . HIS   A 1 256 ? 25.956  30.814  18.328  1.00 27.03 ? 255 HIS   A CD2  1 
ATOM   3805  C  CE1  . HIS   A 1 256 ? 26.051  31.836  20.267  1.00 34.87 ? 255 HIS   A CE1  1 
ATOM   3806  N  NE2  . HIS   A 1 256 ? 26.191  30.662  19.676  1.00 30.23 ? 255 HIS   A NE2  1 
ATOM   3807  H  H    . HIS   A 1 256 ? 24.314  34.005  15.043  1.00 25.09 ? 255 HIS   A H    1 
ATOM   3808  H  HA   . HIS   A 1 256 ? 23.993  31.610  15.894  1.00 26.78 ? 255 HIS   A HA   1 
ATOM   3809  H  HB2  . HIS   A 1 256 ? 26.009  32.679  16.221  1.00 31.10 ? 255 HIS   A HB2  1 
ATOM   3810  H  HB3  . HIS   A 1 256 ? 25.317  33.814  17.091  1.00 31.10 ? 255 HIS   A HB3  1 
ATOM   3811  H  HD2  . HIS   A 1 256 ? 26.000  30.147  17.681  1.00 32.44 ? 255 HIS   A HD2  1 
ATOM   3812  H  HE1  . HIS   A 1 256 ? 26.154  32.003  21.176  1.00 41.85 ? 255 HIS   A HE1  1 
ATOM   3813  H  HE2  . HIS   A 1 256 ? 26.395  29.925  20.069  1.00 36.28 ? 255 HIS   A HE2  1 
ATOM   3814  N  N    . GLY   A 1 257 ? 22.411  31.298  17.681  1.00 21.09 ? 256 GLY   A N    1 
ATOM   3815  C  CA   . GLY   A 1 257 ? 21.443  31.177  18.751  1.00 21.79 ? 256 GLY   A CA   1 
ATOM   3816  C  C    . GLY   A 1 257 ? 20.010  31.470  18.374  1.00 24.19 ? 256 GLY   A C    1 
ATOM   3817  O  O    . GLY   A 1 257 ? 19.160  31.498  19.263  1.00 23.00 ? 256 GLY   A O    1 
ATOM   3818  H  H    . GLY   A 1 257 ? 22.665  30.552  17.336  1.00 25.31 ? 256 GLY   A H    1 
ATOM   3819  H  HA2  . GLY   A 1 257 ? 21.476  30.270  19.094  1.00 26.15 ? 256 GLY   A HA2  1 
ATOM   3820  H  HA3  . GLY   A 1 257 ? 21.690  31.792  19.460  1.00 26.15 ? 256 GLY   A HA3  1 
ATOM   3821  N  N    . THR   A 1 258 ? 19.704  31.697  17.092  1.00 17.07 ? 257 THR   A N    1 
ATOM   3822  C  CA   . THR   A 1 258 ? 18.339  32.003  16.674  1.00 20.96 ? 257 THR   A CA   1 
ATOM   3823  C  C    . THR   A 1 258 ? 17.710  30.895  15.836  1.00 20.66 ? 257 THR   A C    1 
ATOM   3824  O  O    . THR   A 1 258 ? 16.596  31.062  15.345  1.00 21.13 ? 257 THR   A O    1 
ATOM   3825  C  CB   . THR   A 1 258 ? 18.296  33.316  15.890  1.00 23.12 ? 257 THR   A CB   1 
ATOM   3826  O  OG1  . THR   A 1 258 ? 18.926  33.112  14.609  1.00 22.00 ? 257 THR   A OG1  1 
ATOM   3827  C  CG2  . THR   A 1 258 ? 18.955  34.452  16.662  1.00 27.36 ? 257 THR   A CG2  1 
ATOM   3828  H  H    . THR   A 1 258 ? 20.274  31.679  16.449  1.00 20.49 ? 257 THR   A H    1 
ATOM   3829  H  HA   . THR   A 1 258 ? 17.805  32.111  17.477  1.00 25.15 ? 257 THR   A HA   1 
ATOM   3830  H  HB   . THR   A 1 258 ? 17.377  33.591  15.748  1.00 27.75 ? 257 THR   A HB   1 
ATOM   3831  H  HG1  . THR   A 1 258 ? 19.521  33.692  14.486  1.00 26.39 ? 257 THR   A HG1  1 
ATOM   3832  H  HG21 . THR   A 1 258 ? 18.669  35.307  16.303  1.00 32.83 ? 257 THR   A HG21 1 
ATOM   3833  H  HG22 . THR   A 1 258 ? 18.706  34.405  17.598  1.00 32.83 ? 257 THR   A HG22 1 
ATOM   3834  H  HG23 . THR   A 1 258 ? 19.920  34.387  16.589  1.00 32.83 ? 257 THR   A HG23 1 
ATOM   3835  N  N    . PHE   A 1 259 ? 18.394  29.774  15.661  1.00 19.76 ? 258 PHE   A N    1 
ATOM   3836  C  CA   . PHE   A 1 259 ? 17.889  28.665  14.853  1.00 18.52 ? 258 PHE   A CA   1 
ATOM   3837  C  C    . PHE   A 1 259 ? 18.651  27.453  15.359  1.00 17.58 ? 258 PHE   A C    1 
ATOM   3838  O  O    . PHE   A 1 259 ? 19.634  27.591  16.087  1.00 20.54 ? 258 PHE   A O    1 
ATOM   3839  C  CB   . PHE   A 1 259 ? 18.078  28.922  13.345  1.00 18.17 ? 258 PHE   A CB   1 
ATOM   3840  C  CG   . PHE   A 1 259 ? 19.507  28.862  12.923  1.00 17.17 ? 258 PHE   A CG   1 
ATOM   3841  C  CD1  . PHE   A 1 259 ? 20.372  29.886  13.265  1.00 15.30 ? 258 PHE   A CD1  1 
ATOM   3842  C  CD2  . PHE   A 1 259 ? 20.007  27.752  12.222  1.00 17.56 ? 258 PHE   A CD2  1 
ATOM   3843  C  CE1  . PHE   A 1 259 ? 21.742  29.822  12.914  1.00 16.83 ? 258 PHE   A CE1  1 
ATOM   3844  C  CE2  . PHE   A 1 259 ? 21.367  27.697  11.866  1.00 16.50 ? 258 PHE   A CE2  1 
ATOM   3845  C  CZ   . PHE   A 1 259 ? 22.212  28.736  12.203  1.00 18.30 ? 258 PHE   A CZ   1 
ATOM   3846  H  H    . PHE   A 1 259 ? 19.168  29.624  16.005  1.00 23.72 ? 258 PHE   A H    1 
ATOM   3847  H  HA   . PHE   A 1 259 ? 16.936  28.525  14.969  1.00 22.23 ? 258 PHE   A HA   1 
ATOM   3848  H  HB2  . PHE   A 1 259 ? 17.590  28.249  12.846  1.00 21.81 ? 258 PHE   A HB2  1 
ATOM   3849  H  HB3  . PHE   A 1 259 ? 17.739  29.805  13.130  1.00 21.81 ? 258 PHE   A HB3  1 
ATOM   3850  H  HD1  . PHE   A 1 259 ? 20.050  30.624  13.730  1.00 18.37 ? 258 PHE   A HD1  1 
ATOM   3851  H  HD2  . PHE   A 1 259 ? 19.438  27.052  11.992  1.00 21.07 ? 258 PHE   A HD2  1 
ATOM   3852  H  HE1  . PHE   A 1 259 ? 22.322  30.506  13.160  1.00 20.19 ? 258 PHE   A HE1  1 
ATOM   3853  H  HE2  . PHE   A 1 259 ? 21.698  26.961  11.403  1.00 19.80 ? 258 PHE   A HE2  1 
ATOM   3854  H  HZ   . PHE   A 1 259 ? 23.106  28.704  11.948  1.00 21.96 ? 258 PHE   A HZ   1 
ATOM   3855  N  N    . THR   A 1 260 ? 18.200  26.268  14.971  1.00 16.06 ? 259 THR   A N    1 
ATOM   3856  C  CA   . THR   A 1 260 ? 18.900  25.046  15.328  1.00 17.72 ? 259 THR   A CA   1 
ATOM   3857  C  C    . THR   A 1 260 ? 19.900  24.643  14.238  1.00 20.00 ? 259 THR   A C    1 
ATOM   3858  O  O    . THR   A 1 260 ? 21.106  24.518  14.494  1.00 17.42 ? 259 THR   A O    1 
ATOM   3859  C  CB   . THR   A 1 260 ? 17.873  23.939  15.611  1.00 21.11 ? 259 THR   A CB   1 
ATOM   3860  O  OG1  . THR   A 1 260 ? 17.042  24.341  16.727  1.00 20.66 ? 259 THR   A OG1  1 
ATOM   3861  C  CG2  . THR   A 1 260 ? 18.574  22.589  15.870  1.00 18.40 ? 259 THR   A CG2  1 
ATOM   3862  H  H    . THR   A 1 260 ? 17.490  26.147  14.501  1.00 19.27 ? 259 THR   A H    1 
ATOM   3863  H  HA   . THR   A 1 260 ? 19.411  25.182  16.141  1.00 21.27 ? 259 THR   A HA   1 
ATOM   3864  H  HB   . THR   A 1 260 ? 17.300  23.800  14.841  1.00 25.33 ? 259 THR   A HB   1 
ATOM   3865  H  HG1  . THR   A 1 260 ? 17.204  23.858  17.395  1.00 24.79 ? 259 THR   A HG1  1 
ATOM   3866  H  HG21 . THR   A 1 260 ? 18.004  22.018  16.409  1.00 22.08 ? 259 THR   A HG21 1 
ATOM   3867  H  HG22 . THR   A 1 260 ? 18.759  22.144  15.028  1.00 22.08 ? 259 THR   A HG22 1 
ATOM   3868  H  HG23 . THR   A 1 260 ? 19.410  22.734  16.340  1.00 22.08 ? 259 THR   A HG23 1 
ATOM   3869  N  N    . CYS   A 1 261 ? 19.414  24.443  13.025  1.00 15.05 ? 260 CYS   A N    1 
ATOM   3870  C  CA   . CYS   A 1 261 ? 20.322  24.122  11.923  1.00 17.80 ? 260 CYS   A CA   1 
ATOM   3871  C  C    . CYS   A 1 261 ? 19.638  24.495  10.623  1.00 17.89 ? 260 CYS   A C    1 
ATOM   3872  O  O    . CYS   A 1 261 ? 18.438  24.812  10.595  1.00 16.78 ? 260 CYS   A O    1 
ATOM   3873  C  CB   . CYS   A 1 261 ? 20.726  22.655  11.964  1.00 16.18 ? 260 CYS   A CB   1 
ATOM   3874  S  SG   . CYS   A 1 261 ? 19.371  21.482  11.859  1.00 18.62 ? 260 CYS   A SG   1 
ATOM   3875  H  H    . CYS   A 1 261 ? 18.582  24.484  12.813  1.00 18.06 ? 260 CYS   A H    1 
ATOM   3876  H  HA   . CYS   A 1 261 ? 21.131  24.653  11.989  1.00 21.36 ? 260 CYS   A HA   1 
ATOM   3877  H  HB2  . CYS   A 1 261 ? 21.319  22.480  11.217  1.00 19.41 ? 260 CYS   A HB2  1 
ATOM   3878  H  HB3  . CYS   A 1 261 ? 21.189  22.489  12.801  1.00 19.41 ? 260 CYS   A HB3  1 
ATOM   3879  H  HG   . CYS   A 1 261 ? 19.796  20.376  12.048  1.00 22.34 ? 260 CYS   A HG   1 
ATOM   3880  N  N    . ALA   A 1 262 ? 20.409  24.435  9.531   1.00 15.59 ? 261 ALA   A N    1 
ATOM   3881  C  CA   . ALA   A 1 262 ? 19.904  24.889  8.244   1.00 15.03 ? 261 ALA   A CA   1 
ATOM   3882  C  C    . ALA   A 1 262 ? 20.636  24.188  7.111   1.00 15.01 ? 261 ALA   A C    1 
ATOM   3883  O  O    . ALA   A 1 262 ? 21.791  23.742  7.256   1.00 15.10 ? 261 ALA   A O    1 
ATOM   3884  C  CB   . ALA   A 1 262 ? 20.051  26.396  8.102   1.00 16.93 ? 261 ALA   A CB   1 
ATOM   3885  H  H    . ALA   A 1 262 ? 21.216  24.140  9.517   1.00 18.70 ? 261 ALA   A H    1 
ATOM   3886  H  HA   . ALA   A 1 262 ? 18.968  24.646  8.177   1.00 18.04 ? 261 ALA   A HA   1 
ATOM   3887  H  HB1  . ALA   A 1 262 ? 20.188  26.613  7.166   1.00 20.31 ? 261 ALA   A HB1  1 
ATOM   3888  H  HB2  . ALA   A 1 262 ? 19.242  26.824  8.426   1.00 20.31 ? 261 ALA   A HB2  1 
ATOM   3889  H  HB3  . ALA   A 1 262 ? 20.813  26.690  8.625   1.00 20.31 ? 261 ALA   A HB3  1 
ATOM   3890  N  N    . SER   A 1 263 ? 19.956  24.154  5.956   1.00 16.47 ? 262 SER   A N    1 
ATOM   3891  C  CA   . SER   A 1 263 ? 20.468  23.566  4.723   1.00 16.75 ? 262 SER   A CA   1 
ATOM   3892  C  C    . SER   A 1 263 ? 20.878  24.717  3.815   1.00 15.77 ? 262 SER   A C    1 
ATOM   3893  O  O    . SER   A 1 263 ? 20.031  25.508  3.392   1.00 17.44 ? 262 SER   A O    1 
ATOM   3894  C  CB   . SER   A 1 263 ? 19.415  22.706  4.013   1.00 16.94 ? 262 SER   A CB   1 
ATOM   3895  O  OG   . SER   A 1 263 ? 18.899  21.649  4.811   1.00 20.16 ? 262 SER   A OG   1 
ATOM   3896  H  H    . SER   A 1 263 ? 19.165  24.480  5.864   1.00 19.77 ? 262 SER   A H    1 
ATOM   3897  H  HA   . SER   A 1 263 ? 21.227  23.001  4.935   1.00 20.10 ? 262 SER   A HA   1 
ATOM   3898  H  HB2  . SER   A 1 263 ? 18.677  23.281  3.757   1.00 20.33 ? 262 SER   A HB2  1 
ATOM   3899  H  HB3  . SER   A 1 263 ? 19.823  22.319  3.223   1.00 20.33 ? 262 SER   A HB3  1 
ATOM   3900  H  HG   . SER   A 1 263 ? 18.193  21.349  4.468   1.00 24.19 ? 262 SER   A HG   1 
ATOM   3901  N  N    . GLU   A 1 264 ? 22.171  24.816  3.542   1.00 15.75 ? 263 GLU   A N    1 
ATOM   3902  C  CA   . GLU   A 1 264 ? 22.690  25.675  2.481   1.00 15.22 ? 263 GLU   A CA   1 
ATOM   3903  C  C    . GLU   A 1 264 ? 22.670  24.907  1.163   1.00 15.73 ? 263 GLU   A C    1 
ATOM   3904  O  O    . GLU   A 1 264 ? 23.045  23.734  1.111   1.00 17.36 ? 263 GLU   A O    1 
ATOM   3905  C  CB   . GLU   A 1 264 ? 24.128  26.109  2.791   1.00 16.44 ? 263 GLU   A CB   1 
ATOM   3906  C  CG   . GLU   A 1 264 ? 24.761  26.935  1.683   1.00 18.07 ? 263 GLU   A CG   1 
ATOM   3907  C  CD   . GLU   A 1 264 ? 26.247  27.110  1.852   1.00 25.97 ? 263 GLU   A CD   1 
ATOM   3908  O  OE1  . GLU   A 1 264 ? 26.674  27.916  2.700   1.00 25.29 ? 263 GLU   A OE1  1 
ATOM   3909  O  OE2  . GLU   A 1 264 ? 26.987  26.429  1.133   1.00 22.62 ? 263 GLU   A OE2  1 
ATOM   3910  H  H    . GLU   A 1 264 ? 22.784  24.388  3.966   1.00 18.91 ? 263 GLU   A H    1 
ATOM   3911  H  HA   . GLU   A 1 264 ? 22.142  26.471  2.403   1.00 18.26 ? 263 GLU   A HA   1 
ATOM   3912  H  HB2  . GLU   A 1 264 ? 24.126  26.646  3.599   1.00 19.72 ? 263 GLU   A HB2  1 
ATOM   3913  H  HB3  . GLU   A 1 264 ? 24.673  25.317  2.921   1.00 19.72 ? 263 GLU   A HB3  1 
ATOM   3914  H  HG2  . GLU   A 1 264 ? 24.607  26.493  0.834   1.00 21.69 ? 263 GLU   A HG2  1 
ATOM   3915  H  HG3  . GLU   A 1 264 ? 24.355  27.816  1.677   1.00 21.69 ? 263 GLU   A HG3  1 
ATOM   3916  N  N    . TYR   A 1 265 ? 22.274  25.582  0.087   1.00 17.56 ? 264 TYR   A N    1 
ATOM   3917  C  CA   . TYR   A 1 265 ? 22.241  24.950  -1.227  1.00 15.93 ? 264 TYR   A CA   1 
ATOM   3918  C  C    . TYR   A 1 265 ? 22.806  25.914  -2.255  1.00 17.39 ? 264 TYR   A C    1 
ATOM   3919  O  O    . TYR   A 1 265 ? 22.279  27.015  -2.438  1.00 18.04 ? 264 TYR   A O    1 
ATOM   3920  C  CB   . TYR   A 1 265 ? 20.818  24.543  -1.621  1.00 14.79 ? 264 TYR   A CB   1 
ATOM   3921  C  CG   . TYR   A 1 265 ? 20.757  23.755  -2.904  1.00 15.96 ? 264 TYR   A CG   1 
ATOM   3922  C  CD1  . TYR   A 1 265 ? 21.016  22.400  -2.928  1.00 16.27 ? 264 TYR   A CD1  1 
ATOM   3923  C  CD2  . TYR   A 1 265 ? 20.473  24.386  -4.089  1.00 15.03 ? 264 TYR   A CD2  1 
ATOM   3924  C  CE1  . TYR   A 1 265 ? 20.993  21.674  -4.136  1.00 17.97 ? 264 TYR   A CE1  1 
ATOM   3925  C  CE2  . TYR   A 1 265 ? 20.433  23.661  -5.316  1.00 15.93 ? 264 TYR   A CE2  1 
ATOM   3926  C  CZ   . TYR   A 1 265 ? 20.699  22.322  -5.327  1.00 17.40 ? 264 TYR   A CZ   1 
ATOM   3927  O  OH   . TYR   A 1 265 ? 20.653  21.546  -6.494  1.00 17.19 ? 264 TYR   A OH   1 
ATOM   3928  H  H    . TYR   A 1 265 ? 22.022  26.404  0.094   1.00 21.07 ? 264 TYR   A H    1 
ATOM   3929  H  HA   . TYR   A 1 265 ? 22.797  24.155  -1.205  1.00 19.12 ? 264 TYR   A HA   1 
ATOM   3930  H  HB2  . TYR   A 1 265 ? 20.443  23.993  -0.916  1.00 17.75 ? 264 TYR   A HB2  1 
ATOM   3931  H  HB3  . TYR   A 1 265 ? 20.284  25.343  -1.737  1.00 17.75 ? 264 TYR   A HB3  1 
ATOM   3932  H  HD1  . TYR   A 1 265 ? 21.209  21.958  -2.133  1.00 19.52 ? 264 TYR   A HD1  1 
ATOM   3933  H  HD2  . TYR   A 1 265 ? 20.303  25.300  -4.092  1.00 18.04 ? 264 TYR   A HD2  1 
ATOM   3934  H  HE1  . TYR   A 1 265 ? 21.176  20.762  -4.135  1.00 21.56 ? 264 TYR   A HE1  1 
ATOM   3935  H  HE2  . TYR   A 1 265 ? 20.226  24.101  -6.109  1.00 19.12 ? 264 TYR   A HE2  1 
ATOM   3936  H  HH   . TYR   A 1 265 ? 20.094  21.869  -7.032  1.00 20.63 ? 264 TYR   A HH   1 
ATOM   3937  N  N    . THR   A 1 266 ? 23.828  25.451  -2.967  1.00 19.17 ? 265 THR   A N    1 
ATOM   3938  C  CA   . THR   A 1 266 ? 24.472  26.190  -4.046  1.00 16.73 ? 265 THR   A CA   1 
ATOM   3939  C  C    . THR   A 1 266 ? 24.291  25.430  -5.349  1.00 17.18 ? 265 THR   A C    1 
ATOM   3940  O  O    . THR   A 1 266 ? 24.255  24.201  -5.375  1.00 18.62 ? 265 THR   A O    1 
ATOM   3941  C  CB   . THR   A 1 266 ? 25.971  26.419  -3.742  1.00 18.34 ? 265 THR   A CB   1 
ATOM   3942  O  OG1  . THR   A 1 266 ? 26.640  25.165  -3.566  1.00 25.54 ? 265 THR   A OG1  1 
ATOM   3943  C  CG2  . THR   A 1 266 ? 26.150  27.226  -2.508  1.00 20.19 ? 265 THR   A CG2  1 
ATOM   3944  H  H    . THR   A 1 266 ? 24.181  24.678  -2.838  1.00 23.00 ? 265 THR   A H    1 
ATOM   3945  H  HA   . THR   A 1 266 ? 24.060  27.062  -4.151  1.00 20.08 ? 265 THR   A HA   1 
ATOM   3946  H  HB   . THR   A 1 266 ? 26.363  26.897  -4.489  1.00 22.01 ? 265 THR   A HB   1 
ATOM   3947  H  HG1  . THR   A 1 266 ? 26.451  24.842  -2.814  1.00 30.65 ? 265 THR   A HG1  1 
ATOM   3948  H  HG21 . THR   A 1 266 ? 27.006  27.023  -2.100  1.00 24.23 ? 265 THR   A HG21 1 
ATOM   3949  H  HG22 . THR   A 1 266 ? 26.119  28.171  -2.722  1.00 24.23 ? 265 THR   A HG22 1 
ATOM   3950  H  HG23 . THR   A 1 266 ? 25.444  27.024  -1.874  1.00 24.23 ? 265 THR   A HG23 1 
ATOM   3951  N  N    . GLY   A 1 267 ? 24.094  26.170  -6.435  1.00 20.59 ? 266 GLY   A N    1 
ATOM   3952  C  CA   . GLY   A 1 267 ? 23.978  25.531  -7.734  1.00 19.15 ? 266 GLY   A CA   1 
ATOM   3953  C  C    . GLY   A 1 267 ? 22.559  25.588  -8.264  1.00 21.84 ? 266 GLY   A C    1 
ATOM   3954  O  O    . GLY   A 1 267 ? 21.693  26.295  -7.748  1.00 25.25 ? 266 GLY   A O    1 
ATOM   3955  H  H    . GLY   A 1 267 ? 24.027  27.028  -6.442  1.00 24.71 ? 266 GLY   A H    1 
ATOM   3956  H  HA2  . GLY   A 1 267 ? 24.562  25.976  -8.368  1.00 22.98 ? 266 GLY   A HA2  1 
ATOM   3957  H  HA3  . GLY   A 1 267 ? 24.242  24.600  -7.661  1.00 22.98 ? 266 GLY   A HA3  1 
ATOM   3958  N  N    . ASN   A 1 268 ? 22.340  24.861  -9.352  1.00 24.04 ? 267 ASN   A N    1 
ATOM   3959  C  CA   . ASN   A 1 268 ? 21.050  24.826  -10.010 1.00 21.53 ? 267 ASN   A CA   1 
ATOM   3960  C  C    . ASN   A 1 268 ? 20.183  23.703  -9.470  1.00 16.27 ? 267 ASN   A C    1 
ATOM   3961  O  O    . ASN   A 1 268 ? 20.657  22.730  -8.871  1.00 16.84 ? 267 ASN   A O    1 
ATOM   3962  C  CB   . ASN   A 1 268 ? 21.207  24.615  -11.522 1.00 22.46 ? 267 ASN   A CB   1 
ATOM   3963  C  CG   . ASN   A 1 268 ? 21.595  25.865  -12.266 1.00 31.91 ? 267 ASN   A CG   1 
ATOM   3964  O  OD1  . ASN   A 1 268 ? 22.586  26.502  -11.922 1.00 32.01 ? 267 ASN   A OD1  1 
ATOM   3965  N  ND2  . ASN   A 1 268 ? 20.849  26.189  -13.356 1.00 31.50 ? 267 ASN   A ND2  1 
ATOM   3966  H  H    . ASN   A 1 268 ? 22.936  24.371  -9.733  1.00 28.85 ? 267 ASN   A H    1 
ATOM   3967  H  HA   . ASN   A 1 268 ? 20.612  25.676  -9.844  1.00 25.84 ? 267 ASN   A HA   1 
ATOM   3968  H  HB2  . ASN   A 1 268 ? 21.898  23.952  -11.676 1.00 26.95 ? 267 ASN   A HB2  1 
ATOM   3969  H  HB3  . ASN   A 1 268 ? 20.363  24.304  -11.885 1.00 26.95 ? 267 ASN   A HB3  1 
ATOM   3970  H  HD21 . ASN   A 1 268 ? 20.191  25.688  -13.591 1.00 37.80 ? 267 ASN   A HD21 1 
ATOM   3971  H  HD22 . ASN   A 1 268 ? 21.036  26.895  -13.810 1.00 37.80 ? 267 ASN   A HD22 1 
ATOM   3972  N  N    . TYR   A 1 269 ? 18.889  23.830  -9.743  1.00 20.66 ? 268 TYR   A N    1 
ATOM   3973  C  CA   . TYR   A 1 269 ? 17.908  22.813  -9.404  1.00 18.62 ? 268 TYR   A CA   1 
ATOM   3974  C  C    . TYR   A 1 269 ? 18.345  21.426  -9.814  1.00 21.19 ? 268 TYR   A C    1 
ATOM   3975  O  O    . TYR   A 1 269 ? 18.679  21.163  -10.975 1.00 18.82 ? 268 TYR   A O    1 
ATOM   3976  C  CB   . TYR   A 1 269 ? 16.597  23.187  -10.079 1.00 21.93 ? 268 TYR   A CB   1 
ATOM   3977  C  CG   . TYR   A 1 269 ? 15.364  22.429  -9.719  1.00 23.31 ? 268 TYR   A CG   1 
ATOM   3978  C  CD1  . TYR   A 1 269 ? 14.774  22.545  -8.442  1.00 20.37 ? 268 TYR   A CD1  1 
ATOM   3979  C  CD2  . TYR   A 1 269 ? 14.727  21.643  -10.655 1.00 23.28 ? 268 TYR   A CD2  1 
ATOM   3980  C  CE1  . TYR   A 1 269 ? 13.599  21.908  -8.152  1.00 21.52 ? 268 TYR   A CE1  1 
ATOM   3981  C  CE2  . TYR   A 1 269 ? 13.534  20.986  -10.359 1.00 26.79 ? 268 TYR   A CE2  1 
ATOM   3982  C  CZ   . TYR   A 1 269 ? 12.976  21.124  -9.114  1.00 28.51 ? 268 TYR   A CZ   1 
ATOM   3983  O  OH   . TYR   A 1 269 ? 11.806  20.476  -8.818  1.00 30.32 ? 268 TYR   A OH   1 
ATOM   3984  H  H    . TYR   A 1 269 ? 18.547  24.515  -10.135 1.00 24.80 ? 268 TYR   A H    1 
ATOM   3985  H  HA   . TYR   A 1 269 ? 17.791  22.781  -8.441  1.00 22.34 ? 268 TYR   A HA   1 
ATOM   3986  H  HB2  . TYR   A 1 269 ? 16.417  24.118  -9.873  1.00 26.32 ? 268 TYR   A HB2  1 
ATOM   3987  H  HB3  . TYR   A 1 269 ? 16.718  23.077  -11.035 1.00 26.32 ? 268 TYR   A HB3  1 
ATOM   3988  H  HD1  . TYR   A 1 269 ? 15.190  23.062  -7.789  1.00 24.45 ? 268 TYR   A HD1  1 
ATOM   3989  H  HD2  . TYR   A 1 269 ? 15.101  21.549  -11.501 1.00 27.94 ? 268 TYR   A HD2  1 
ATOM   3990  H  HE1  . TYR   A 1 269 ? 13.217  21.999  -7.309  1.00 25.82 ? 268 TYR   A HE1  1 
ATOM   3991  H  HE2  . TYR   A 1 269 ? 13.120  20.457  -11.002 1.00 32.15 ? 268 TYR   A HE2  1 
ATOM   3992  H  HH   . TYR   A 1 269 ? 11.511  20.740  -8.077  1.00 36.38 ? 268 TYR   A HH   1 
ATOM   3993  N  N    . GLN   A 1 270 ? 18.323  20.515  -8.845  1.00 15.60 ? 269 GLN   A N    1 
ATOM   3994  C  CA   . GLN   A 1 270 ? 18.596  19.098  -9.007  1.00 18.32 ? 269 GLN   A CA   1 
ATOM   3995  C  C    . GLN   A 1 270 ? 20.065  18.792  -9.312  1.00 19.52 ? 269 GLN   A C    1 
ATOM   3996  O  O    . GLN   A 1 270 ? 20.401  17.616  -9.518  1.00 20.83 ? 269 GLN   A O    1 
ATOM   3997  C  CB   . GLN   A 1 270 ? 17.733  18.461  -10.104 1.00 20.05 ? 269 GLN   A CB   1 
ATOM   3998  C  CG   . GLN   A 1 270 ? 16.277  18.368  -9.774  1.00 20.21 ? 269 GLN   A CG   1 
ATOM   3999  C  CD   . GLN   A 1 270 ? 15.496  17.485  -10.781 1.00 25.73 ? 269 GLN   A CD   1 
ATOM   4000  O  OE1  . GLN   A 1 270 ? 14.969  17.994  -11.763 1.00 35.90 ? 269 GLN   A OE1  1 
ATOM   4001  N  NE2  . GLN   A 1 270 ? 15.510  16.177  -10.578 1.00 32.26 ? 269 GLN   A NE2  1 
ATOM   4002  N  N    . CYS   A 1 271 ? 20.970  19.776  -9.319  1.00 18.76 ? 270 CYS   A N    1 
ATOM   4003  C  CA   . CYS   A 1 271 ? 22.349  19.440  -9.662  1.00 19.85 ? 270 CYS   A CA   1 
ATOM   4004  C  C    . CYS   A 1 271 ? 23.392  20.245  -8.902  1.00 19.30 ? 270 CYS   A C    1 
ATOM   4005  O  O    . CYS   A 1 271 ? 24.521  20.422  -9.379  1.00 19.28 ? 270 CYS   A O    1 
ATOM   4006  C  CB   . CYS   A 1 271 ? 22.564  19.536  -11.184 1.00 32.97 ? 270 CYS   A CB   1 
ATOM   4007  S  SG   . CYS   A 1 271 ? 22.083  21.098  -11.856 1.00 26.63 ? 270 CYS   A SG   1 
ATOM   4008  H  H    . CYS   A 1 271 ? 20.816  20.603  -9.137  1.00 22.51 ? 270 CYS   A H    1 
ATOM   4009  H  HA   . CYS   A 1 271 ? 22.505  18.521  -9.394  1.00 23.83 ? 270 CYS   A HA   1 
ATOM   4010  H  HB2  . CYS   A 1 271 ? 23.505  19.404  -11.377 1.00 39.56 ? 270 CYS   A HB2  1 
ATOM   4011  H  HB3  . CYS   A 1 271 ? 22.037  18.848  -11.619 1.00 39.56 ? 270 CYS   A HB3  1 
ATOM   4012  N  N    . GLY   A 1 272 ? 23.071  20.688  -7.681  1.00 17.15 ? 271 GLY   A N    1 
ATOM   4013  C  CA   . GLY   A 1 272 ? 23.959  21.501  -6.890  1.00 18.62 ? 271 GLY   A CA   1 
ATOM   4014  C  C    . GLY   A 1 272 ? 24.577  20.767  -5.703  1.00 18.40 ? 271 GLY   A C    1 
ATOM   4015  O  O    . GLY   A 1 272 ? 24.918  19.576  -5.787  1.00 19.04 ? 271 GLY   A O    1 
ATOM   4016  H  H    . GLY   A 1 272 ? 22.324  20.521  -7.290  1.00 20.58 ? 271 GLY   A H    1 
ATOM   4017  H  HA2  . GLY   A 1 272 ? 24.681  21.819  -7.454  1.00 22.35 ? 271 GLY   A HA2  1 
ATOM   4018  H  HA3  . GLY   A 1 272 ? 23.467  22.263  -6.547  1.00 22.35 ? 271 GLY   A HA3  1 
ATOM   4019  N  N    . HIS   A 1 273 ? 24.761  21.498  -4.617  1.00 18.61 ? 272 HIS   A N    1 
ATOM   4020  C  CA   . HIS   A 1 273 ? 25.502  20.956  -3.493  1.00 15.64 ? 272 HIS   A CA   1 
ATOM   4021  C  C    . HIS   A 1 273 ? 24.907  21.501  -2.209  1.00 16.38 ? 272 HIS   A C    1 
ATOM   4022  O  O    . HIS   A 1 273 ? 24.718  22.713  -2.065  1.00 15.10 ? 272 HIS   A O    1 
ATOM   4023  C  CB   . HIS   A 1 273 ? 26.971  21.323  -3.602  1.00 18.38 ? 272 HIS   A CB   1 
ATOM   4024  C  CG   . HIS   A 1 273 ? 27.816  20.756  -2.523  1.00 16.93 ? 272 HIS   A CG   1 
ATOM   4025  N  ND1  . HIS   A 1 273 ? 28.101  19.412  -2.437  1.00 20.34 ? 272 HIS   A ND1  1 
ATOM   4026  C  CD2  . HIS   A 1 273 ? 28.402  21.341  -1.446  1.00 19.09 ? 272 HIS   A CD2  1 
ATOM   4027  C  CE1  . HIS   A 1 273 ? 28.837  19.194  -1.356  1.00 21.27 ? 272 HIS   A CE1  1 
ATOM   4028  N  NE2  . HIS   A 1 273 ? 29.052  20.350  -0.752  1.00 19.27 ? 272 HIS   A NE2  1 
ATOM   4029  H  H    . HIS   A 1 273 ? 24.470  22.300  -4.508  1.00 22.33 ? 272 HIS   A H    1 
ATOM   4030  H  HA   . HIS   A 1 273 ? 25.424  19.989  -3.473  1.00 18.77 ? 272 HIS   A HA   1 
ATOM   4031  H  HB2  . HIS   A 1 273 ? 27.312  20.993  -4.448  1.00 22.06 ? 272 HIS   A HB2  1 
ATOM   4032  H  HB3  . HIS   A 1 273 ? 27.054  22.289  -3.565  1.00 22.06 ? 272 HIS   A HB3  1 
ATOM   4033  H  HD2  . HIS   A 1 273 ? 28.369  22.242  -1.221  1.00 22.91 ? 272 HIS   A HD2  1 
ATOM   4034  H  HE1  . HIS   A 1 273 ? 29.150  18.366  -1.071  1.00 25.53 ? 272 HIS   A HE1  1 
ATOM   4035  H  HE2  . HIS   A 1 273 ? 29.522  20.463  -0.041  1.00 23.12 ? 272 HIS   A HE2  1 
ATOM   4036  N  N    . TYR   A 1 274 ? 24.641  20.600  -1.291  1.00 12.95 ? 273 TYR   A N    1 
ATOM   4037  C  CA   . TYR   A 1 274 ? 24.227  21.005  0.049   1.00 14.47 ? 273 TYR   A CA   1 
ATOM   4038  C  C    . TYR   A 1 274 ? 25.401  21.076  1.024   1.00 16.27 ? 273 TYR   A C    1 
ATOM   4039  O  O    . TYR   A 1 274 ? 26.337  20.257  0.968   1.00 17.15 ? 273 TYR   A O    1 
ATOM   4040  C  CB   . TYR   A 1 274 ? 23.236  19.998  0.604   1.00 17.50 ? 273 TYR   A CB   1 
ATOM   4041  C  CG   . TYR   A 1 274 ? 21.805  20.063  0.137   1.00 15.52 ? 273 TYR   A CG   1 
ATOM   4042  C  CD1  . TYR   A 1 274 ? 20.907  20.953  0.681   1.00 14.95 ? 273 TYR   A CD1  1 
ATOM   4043  C  CD2  . TYR   A 1 274 ? 21.336  19.177  -0.841  1.00 13.80 ? 273 TYR   A CD2  1 
ATOM   4044  C  CE1  . TYR   A 1 274 ? 19.568  20.954  0.275   1.00 13.51 ? 273 TYR   A CE1  1 
ATOM   4045  C  CE2  . TYR   A 1 274 ? 20.004  19.176  -1.236  1.00 14.83 ? 273 TYR   A CE2  1 
ATOM   4046  C  CZ   . TYR   A 1 274 ? 19.140  20.059  -0.693  1.00 13.47 ? 273 TYR   A CZ   1 
ATOM   4047  O  OH   . TYR   A 1 274 ? 17.825  20.043  -1.073  1.00 14.95 ? 273 TYR   A OH   1 
ATOM   4048  H  H    . TYR   A 1 274 ? 24.691  19.750  -1.410  1.00 15.54 ? 273 TYR   A H    1 
ATOM   4049  H  HA   . TYR   A 1 274 ? 23.831  21.888  -0.016  1.00 17.37 ? 273 TYR   A HA   1 
ATOM   4050  H  HB2  . TYR   A 1 274 ? 23.559  19.112  0.376   1.00 21.00 ? 273 TYR   A HB2  1 
ATOM   4051  H  HB3  . TYR   A 1 274 ? 23.216  20.106  1.568   1.00 21.00 ? 273 TYR   A HB3  1 
ATOM   4052  H  HD1  . TYR   A 1 274 ? 21.193  21.560  1.324   1.00 17.94 ? 273 TYR   A HD1  1 
ATOM   4053  H  HD2  . TYR   A 1 274 ? 21.929  18.577  -1.235  1.00 16.56 ? 273 TYR   A HD2  1 
ATOM   4054  H  HE1  . TYR   A 1 274 ? 18.966  21.555  0.653   1.00 16.21 ? 273 TYR   A HE1  1 
ATOM   4055  H  HE2  . TYR   A 1 274 ? 19.708  18.568  -1.874  1.00 17.80 ? 273 TYR   A HE2  1 
ATOM   4056  H  HH   . TYR   A 1 274 ? 17.335  20.243  -0.420  1.00 17.95 ? 273 TYR   A HH   1 
ATOM   4057  N  N    . LYS   A 1 275 ? 25.293  22.022  1.968   1.00 16.99 ? 274 LYS   A N    1 
ATOM   4058  C  CA   . LYS   A 1 275 ? 26.081  22.060  3.189   1.00 18.32 ? 274 LYS   A CA   1 
ATOM   4059  C  C    . LYS   A 1 275 ? 25.115  22.268  4.351   1.00 15.71 ? 274 LYS   A C    1 
ATOM   4060  O  O    . LYS   A 1 275 ? 23.968  22.679  4.168   1.00 15.91 ? 274 LYS   A O    1 
ATOM   4061  C  CB   . LYS   A 1 275 ? 27.093  23.179  3.162   1.00 19.38 ? 274 LYS   A CB   1 
ATOM   4062  C  CG   . LYS   A 1 275 ? 28.171  22.998  2.057   1.00 19.90 ? 274 LYS   A CG   1 
ATOM   4063  C  CD   . LYS   A 1 275 ? 29.214  24.101  2.130   1.00 20.10 ? 274 LYS   A CD   1 
ATOM   4064  C  CE   . LYS   A 1 275 ? 29.924  24.320  0.778   1.00 26.62 ? 274 LYS   A CE   1 
ATOM   4065  N  NZ   . LYS   A 1 275 ? 30.902  25.476  0.896   1.00 27.75 ? 274 LYS   A NZ   1 
ATOM   4066  H  H    . LYS   A 1 275 ? 24.741  22.680  1.914   1.00 20.39 ? 274 LYS   A H    1 
ATOM   4067  H  HA   . LYS   A 1 275 ? 26.566  21.229  3.309   1.00 21.98 ? 274 LYS   A HA   1 
ATOM   4068  H  HB2  . LYS   A 1 275 ? 26.633  24.016  2.997   1.00 23.26 ? 274 LYS   A HB2  1 
ATOM   4069  H  HB3  . LYS   A 1 275 ? 27.547  23.214  4.019   1.00 23.26 ? 274 LYS   A HB3  1 
ATOM   4070  H  HG2  . LYS   A 1 275 ? 28.616  22.145  2.176   1.00 23.89 ? 274 LYS   A HG2  1 
ATOM   4071  H  HG3  . LYS   A 1 275 ? 27.748  23.032  1.185   1.00 23.89 ? 274 LYS   A HG3  1 
ATOM   4072  H  HD2  . LYS   A 1 275 ? 28.782  24.932  2.384   1.00 24.13 ? 274 LYS   A HD2  1 
ATOM   4073  H  HD3  . LYS   A 1 275 ? 29.885  23.862  2.789   1.00 24.13 ? 274 LYS   A HD3  1 
ATOM   4074  H  HE2  . LYS   A 1 275 ? 30.413  23.520  0.530   1.00 31.94 ? 274 LYS   A HE2  1 
ATOM   4075  H  HE3  . LYS   A 1 275 ? 29.269  24.534  0.094   1.00 31.94 ? 274 LYS   A HE3  1 
ATOM   4076  H  HZ1  . LYS   A 1 275 ? 31.322  25.600  0.121   1.00 33.30 ? 274 LYS   A HZ1  1 
ATOM   4077  H  HZ2  . LYS   A 1 275 ? 30.468  26.222  1.112   1.00 33.30 ? 274 LYS   A HZ2  1 
ATOM   4078  H  HZ3  . LYS   A 1 275 ? 31.505  25.300  1.527   1.00 33.30 ? 274 LYS   A HZ3  1 
ATOM   4079  N  N    . HIS   A 1 276 ? 25.600  21.966  5.553   1.00 18.86 ? 275 HIS   A N    1 
ATOM   4080  C  CA   . HIS   A 1 276 ? 24.803  21.987  6.767   1.00 18.09 ? 275 HIS   A CA   1 
ATOM   4081  C  C    . HIS   A 1 276 ? 25.338  23.066  7.695   1.00 14.82 ? 275 HIS   A C    1 
ATOM   4082  O  O    . HIS   A 1 276 ? 26.533  23.051  8.047   1.00 16.91 ? 275 HIS   A O    1 
ATOM   4083  C  CB   . HIS   A 1 276 ? 24.873  20.621  7.447   1.00 17.64 ? 275 HIS   A CB   1 
ATOM   4084  C  CG   . HIS   A 1 276 ? 24.109  20.551  8.721   1.00 18.54 ? 275 HIS   A CG   1 
ATOM   4085  N  ND1  . HIS   A 1 276 ? 22.764  20.250  8.754   1.00 17.77 ? 275 HIS   A ND1  1 
ATOM   4086  C  CD2  . HIS   A 1 276 ? 24.502  20.680  10.009  1.00 18.98 ? 275 HIS   A CD2  1 
ATOM   4087  C  CE1  . HIS   A 1 276 ? 22.353  20.227  10.014  1.00 18.34 ? 275 HIS   A CE1  1 
ATOM   4088  N  NE2  . HIS   A 1 276 ? 23.380  20.510  10.792  1.00 17.24 ? 275 HIS   A NE2  1 
ATOM   4089  H  H    . HIS   A 1 276 ? 26.417  21.737  5.691   1.00 22.64 ? 275 HIS   A H    1 
ATOM   4090  H  HA   . HIS   A 1 276 ? 23.881  22.203  6.559   1.00 21.71 ? 275 HIS   A HA   1 
ATOM   4091  H  HB2  . HIS   A 1 276 ? 24.508  19.953  6.845   1.00 21.17 ? 275 HIS   A HB2  1 
ATOM   4092  H  HB3  . HIS   A 1 276 ? 25.800  20.417  7.645   1.00 21.17 ? 275 HIS   A HB3  1 
ATOM   4093  H  HD1  . HIS   A 1 276 ? 22.269  20.102  8.066   1.00 21.33 ? 275 HIS   A HD1  1 
ATOM   4094  H  HD2  . HIS   A 1 276 ? 25.366  20.851  10.310  1.00 22.77 ? 275 HIS   A HD2  1 
ATOM   4095  H  HE1  . HIS   A 1 276 ? 21.488  20.041  10.300  1.00 22.01 ? 275 HIS   A HE1  1 
ATOM   4096  N  N    . ILE   A 1 277 ? 24.471  23.995  8.089   1.00 13.97 ? 276 ILE   A N    1 
ATOM   4097  C  CA   . ILE   A 1 277 ? 24.831  25.053  9.036   1.00 15.20 ? 276 ILE   A CA   1 
ATOM   4098  C  C    . ILE   A 1 277 ? 24.194  24.743  10.392  1.00 16.43 ? 276 ILE   A C    1 
ATOM   4099  O  O    . ILE   A 1 277 ? 22.981  24.508  10.460  1.00 14.19 ? 276 ILE   A O    1 
ATOM   4100  C  CB   . ILE   A 1 277 ? 24.387  26.445  8.564   1.00 16.77 ? 276 ILE   A CB   1 
ATOM   4101  C  CG1  . ILE   A 1 277 ? 24.702  26.713  7.080   1.00 21.02 ? 276 ILE   A CG1  1 
ATOM   4102  C  CG2  . ILE   A 1 277 ? 24.954  27.509  9.516   1.00 20.29 ? 276 ILE   A CG2  1 
ATOM   4103  C  CD1  . ILE   A 1 277 ? 26.159  26.628  6.746   1.00 20.14 ? 276 ILE   A CD1  1 
ATOM   4104  H  H    . ILE   A 1 277 ? 23.656  24.035  7.818   1.00 16.77 ? 276 ILE   A H    1 
ATOM   4105  H  HA   . ILE   A 1 277 ? 25.797  25.049  9.127   1.00 18.24 ? 276 ILE   A HA   1 
ATOM   4106  H  HB   . ILE   A 1 277 ? 23.419  26.486  8.605   1.00 20.12 ? 276 ILE   A HB   1 
ATOM   4107  H  HG12 . ILE   A 1 277 ? 24.235  26.057  6.539   1.00 25.23 ? 276 ILE   A HG12 1 
ATOM   4108  H  HG13 . ILE   A 1 277 ? 24.398  27.606  6.853   1.00 25.23 ? 276 ILE   A HG13 1 
ATOM   4109  H  HG21 . ILE   A 1 277 ? 24.952  28.368  9.067   1.00 24.34 ? 276 ILE   A HG21 1 
ATOM   4110  H  HG22 . ILE   A 1 277 ? 24.398  27.550  10.310  1.00 24.34 ? 276 ILE   A HG22 1 
ATOM   4111  H  HG23 . ILE   A 1 277 ? 25.860  27.264  9.760   1.00 24.34 ? 276 ILE   A HG23 1 
ATOM   4112  H  HD11 . ILE   A 1 277 ? 26.274  26.771  5.794   1.00 24.17 ? 276 ILE   A HD11 1 
ATOM   4113  H  HD12 . ILE   A 1 277 ? 26.637  27.310  7.243   1.00 24.17 ? 276 ILE   A HD12 1 
ATOM   4114  H  HD13 . ILE   A 1 277 ? 26.488  25.749  6.990   1.00 24.17 ? 276 ILE   A HD13 1 
ATOM   4115  N  N    . THR   A 1 278 ? 24.989  24.772  11.473  1.00 16.01 ? 277 THR   A N    1 
ATOM   4116  C  CA   . THR   A 1 278 ? 24.433  24.580  12.817  1.00 17.22 ? 277 THR   A CA   1 
ATOM   4117  C  C    . THR   A 1 278 ? 24.982  25.639  13.761  1.00 23.99 ? 277 THR   A C    1 
ATOM   4118  O  O    . THR   A 1 278 ? 26.009  26.266  13.513  1.00 23.16 ? 277 THR   A O    1 
ATOM   4119  C  CB   . THR   A 1 278 ? 24.653  23.140  13.341  1.00 19.23 ? 277 THR   A CB   1 
ATOM   4120  O  OG1  . THR   A 1 278 ? 24.034  23.001  14.640  1.00 22.84 ? 277 THR   A OG1  1 
ATOM   4121  C  CG2  . THR   A 1 278 ? 26.099  22.775  13.483  1.00 18.02 ? 277 THR   A CG2  1 
ATOM   4122  H  H    . THR   A 1 278 ? 25.839  24.900  11.451  1.00 19.21 ? 277 THR   A H    1 
ATOM   4123  H  HA   . THR   A 1 278 ? 23.472  24.710  12.794  1.00 20.66 ? 277 THR   A HA   1 
ATOM   4124  H  HB   . THR   A 1 278 ? 24.261  22.536  12.691  1.00 23.08 ? 277 THR   A HB   1 
ATOM   4125  H  HG1  . THR   A 1 278 ? 23.204  23.113  14.577  1.00 27.41 ? 277 THR   A HG1  1 
ATOM   4126  H  HG21 . THR   A 1 278 ? 26.183  21.837  13.716  1.00 21.62 ? 277 THR   A HG21 1 
ATOM   4127  H  HG22 . THR   A 1 278 ? 26.565  22.936  12.648  1.00 21.62 ? 277 THR   A HG22 1 
ATOM   4128  H  HG23 . THR   A 1 278 ? 26.508  23.310  14.181  1.00 21.62 ? 277 THR   A HG23 1 
ATOM   4129  N  N    . SER   A 1 279 ? 24.223  25.899  14.810  1.00 23.41 ? 278 SER   A N    1 
ATOM   4130  C  CA   . SER   A 1 279 ? 24.552  26.916  15.791  1.00 17.50 ? 278 SER   A CA   1 
ATOM   4131  C  C    . SER   A 1 279 ? 24.968  26.236  17.093  1.00 25.80 ? 278 SER   A C    1 
ATOM   4132  O  O    . SER   A 1 279 ? 24.174  25.503  17.676  1.00 22.38 ? 278 SER   A O    1 
ATOM   4133  C  CB   . SER   A 1 279 ? 23.341  27.825  16.013  1.00 22.86 ? 278 SER   A CB   1 
ATOM   4134  O  OG   . SER   A 1 279 ? 23.607  28.824  16.991  1.00 22.02 ? 278 SER   A OG   1 
ATOM   4135  H  H    . SER   A 1 279 ? 23.488  25.487  14.981  1.00 28.09 ? 278 SER   A H    1 
ATOM   4136  H  HA   . SER   A 1 279 ? 25.301  27.450  15.485  1.00 21.00 ? 278 SER   A HA   1 
ATOM   4137  H  HB2  . SER   A 1 279 ? 23.119  28.260  15.175  1.00 27.43 ? 278 SER   A HB2  1 
ATOM   4138  H  HB3  . SER   A 1 279 ? 22.595  27.284  16.314  1.00 27.43 ? 278 SER   A HB3  1 
ATOM   4139  H  HG   . SER   A 1 279 ? 23.997  29.477  16.635  1.00 26.42 ? 278 SER   A HG   1 
ATOM   4140  N  N    . LYS   A 1 280 ? 26.215  26.474  17.529  1.00 20.84 ? 279 LYS   A N    1 
ATOM   4141  C  CA   . LYS   A 1 280 ? 26.770  25.908  18.757  1.00 27.15 ? 279 LYS   A CA   1 
ATOM   4142  C  C    . LYS   A 1 280 ? 27.297  27.083  19.579  1.00 25.55 ? 279 LYS   A C    1 
ATOM   4143  O  O    . LYS   A 1 280 ? 26.541  28.010  19.849  1.00 27.37 ? 279 LYS   A O    1 
ATOM   4144  C  CB   . LYS   A 1 280 ? 27.857  24.891  18.426  1.00 28.07 ? 279 LYS   A CB   1 
ATOM   4145  C  CG   . LYS   A 1 280 ? 27.378  23.638  17.680  1.00 30.87 ? 279 LYS   A CG   1 
ATOM   4146  C  CD   . LYS   A 1 280 ? 26.449  22.807  18.559  1.00 34.82 ? 279 LYS   A CD   1 
ATOM   4147  C  CE   . LYS   A 1 280 ? 25.497  21.960  17.721  1.00 35.19 ? 279 LYS   A CE   1 
ATOM   4148  N  NZ   . LYS   A 1 280 ? 24.086  22.490  17.741  1.00 34.60 ? 279 LYS   A NZ   1 
ATOM   4149  H  H    . LYS   A 1 280 ? 26.774  26.979  17.114  1.00 25.00 ? 279 LYS   A H    1 
ATOM   4150  H  HA   . LYS   A 1 280 ? 26.112  25.419  19.275  1.00 32.58 ? 279 LYS   A HA   1 
ATOM   4151  H  HB2  . LYS   A 1 280 ? 28.521  25.324  17.868  1.00 33.68 ? 279 LYS   A HB2  1 
ATOM   4152  H  HB3  . LYS   A 1 280 ? 28.263  24.596  19.257  1.00 33.68 ? 279 LYS   A HB3  1 
ATOM   4153  H  HG2  . LYS   A 1 280 ? 26.893  23.902  16.883  1.00 37.04 ? 279 LYS   A HG2  1 
ATOM   4154  H  HG3  . LYS   A 1 280 ? 28.143  23.093  17.439  1.00 37.04 ? 279 LYS   A HG3  1 
ATOM   4155  H  HD2  . LYS   A 1 280 ? 26.978  22.212  19.114  1.00 41.78 ? 279 LYS   A HD2  1 
ATOM   4156  H  HD3  . LYS   A 1 280 ? 25.921  23.398  19.118  1.00 41.78 ? 279 LYS   A HD3  1 
ATOM   4157  H  HE2  . LYS   A 1 280 ? 25.803  21.955  16.800  1.00 42.22 ? 279 LYS   A HE2  1 
ATOM   4158  H  HE3  . LYS   A 1 280 ? 25.484  21.056  18.071  1.00 42.22 ? 279 LYS   A HE3  1 
ATOM   4159  H  HZ1  . LYS   A 1 280 ? 23.805  22.639  16.910  1.00 41.51 ? 279 LYS   A HZ1  1 
ATOM   4160  H  HZ2  . LYS   A 1 280 ? 23.544  21.899  18.127  1.00 41.51 ? 279 LYS   A HZ2  1 
ATOM   4161  H  HZ3  . LYS   A 1 280 ? 24.054  23.253  18.198  1.00 41.51 ? 279 LYS   A HZ3  1 
ATOM   4162  N  N    . GLU   A 1 281 ? 28.606  27.137  19.860  1.00 26.59 ? 280 GLU   A N    1 
ATOM   4163  C  CA   . GLU   A 1 281 ? 29.168  28.345  20.450  1.00 27.04 ? 280 GLU   A CA   1 
ATOM   4164  C  C    . GLU   A 1 281 ? 29.374  29.428  19.417  1.00 30.00 ? 280 GLU   A C    1 
ATOM   4165  O  O    . GLU   A 1 281 ? 29.554  30.586  19.780  1.00 26.23 ? 280 GLU   A O    1 
ATOM   4166  C  CB   . GLU   A 1 281 ? 30.496  28.059  21.169  1.00 31.10 ? 280 GLU   A CB   1 
ATOM   4167  C  CG   . GLU   A 1 281 ? 31.749  28.035  20.303  1.00 28.28 ? 280 GLU   A CG   1 
ATOM   4168  C  CD   . GLU   A 1 281 ? 31.926  26.763  19.478  1.00 31.05 ? 280 GLU   A CD   1 
ATOM   4169  O  OE1  . GLU   A 1 281 ? 31.147  25.781  19.650  1.00 26.10 ? 280 GLU   A OE1  1 
ATOM   4170  O  OE2  . GLU   A 1 281 ? 32.890  26.754  18.672  1.00 32.70 ? 280 GLU   A OE2  1 
ATOM   4171  H  H    . GLU   A 1 281 ? 29.169  26.502  19.721  1.00 31.91 ? 280 GLU   A H    1 
ATOM   4172  H  HA   . GLU   A 1 281 ? 28.553  28.668  21.127  1.00 32.45 ? 280 GLU   A HA   1 
ATOM   4173  H  HB2  . GLU   A 1 281 ? 30.628  28.747  21.841  1.00 37.33 ? 280 GLU   A HB2  1 
ATOM   4174  H  HB3  . GLU   A 1 281 ? 30.427  27.190  21.593  1.00 37.33 ? 280 GLU   A HB3  1 
ATOM   4175  H  HG2  . GLU   A 1 281 ? 31.712  28.781  19.685  1.00 33.94 ? 280 GLU   A HG2  1 
ATOM   4176  H  HG3  . GLU   A 1 281 ? 32.524  28.119  20.880  1.00 33.94 ? 280 GLU   A HG3  1 
ATOM   4177  N  N    . THR   A 1 282 ? 29.412  29.050  18.142  1.00 21.83 ? 281 THR   A N    1 
ATOM   4178  C  CA   . THR   A 1 282 ? 29.448  29.945  16.997  1.00 23.87 ? 281 THR   A CA   1 
ATOM   4179  C  C    . THR   A 1 282 ? 28.749  29.198  15.852  1.00 19.64 ? 281 THR   A C    1 
ATOM   4180  O  O    . THR   A 1 282 ? 28.175  28.121  16.054  1.00 21.83 ? 281 THR   A O    1 
ATOM   4181  C  CB   . THR   A 1 282 ? 30.903  30.341  16.706  1.00 22.61 ? 281 THR   A CB   1 
ATOM   4182  O  OG1  . THR   A 1 282 ? 30.924  31.415  15.782  1.00 23.53 ? 281 THR   A OG1  1 
ATOM   4183  C  CG2  . THR   A 1 282 ? 31.688  29.189  16.168  1.00 23.41 ? 281 THR   A CG2  1 
ATOM   4184  H  H    . THR   A 1 282 ? 29.418  28.224  17.902  1.00 26.19 ? 281 THR   A H    1 
ATOM   4185  H  HA   . THR   A 1 282 ? 28.958  30.765  17.163  1.00 28.65 ? 281 THR   A HA   1 
ATOM   4186  H  HB   . THR   A 1 282 ? 31.330  30.617  17.533  1.00 27.13 ? 281 THR   A HB   1 
ATOM   4187  H  HG1  . THR   A 1 282 ? 31.432  31.231  15.139  1.00 28.24 ? 281 THR   A HG1  1 
ATOM   4188  H  HG21 . THR   A 1 282 ? 32.637  29.347  16.292  1.00 28.09 ? 281 THR   A HG21 1 
ATOM   4189  H  HG22 . THR   A 1 282 ? 31.441  28.374  16.633  1.00 28.09 ? 281 THR   A HG22 1 
ATOM   4190  H  HG23 . THR   A 1 282 ? 31.508  29.078  15.221  1.00 28.09 ? 281 THR   A HG23 1 
ATOM   4191  N  N    . LEU   A 1 283 ? 28.797  29.739  14.643  1.00 21.48 ? 282 LEU   A N    1 
ATOM   4192  C  CA   . LEU   A 1 283 ? 28.178  29.055  13.517  1.00 20.89 ? 282 LEU   A CA   1 
ATOM   4193  C  C    . LEU   A 1 283 ? 29.141  28.035  12.915  1.00 22.89 ? 282 LEU   A C    1 
ATOM   4194  O  O    . LEU   A 1 283 ? 30.299  28.351  12.648  1.00 25.84 ? 282 LEU   A O    1 
ATOM   4195  C  CB   . LEU   A 1 283 ? 27.731  30.063  12.466  1.00 20.27 ? 282 LEU   A CB   1 
ATOM   4196  C  CG   . LEU   A 1 283 ? 26.797  31.157  12.978  1.00 24.18 ? 282 LEU   A CG   1 
ATOM   4197  C  CD1  . LEU   A 1 283 ? 26.452  32.173  11.926  1.00 25.67 ? 282 LEU   A CD1  1 
ATOM   4198  C  CD2  . LEU   A 1 283 ? 25.540  30.559  13.574  1.00 29.65 ? 282 LEU   A CD2  1 
ATOM   4199  H  H    . LEU   A 1 283 ? 29.176  30.488  14.453  1.00 25.78 ? 282 LEU   A H    1 
ATOM   4200  H  HA   . LEU   A 1 283 ? 27.398  28.570  13.827  1.00 25.06 ? 282 LEU   A HA   1 
ATOM   4201  H  HB2  . LEU   A 1 283 ? 28.519  30.498  12.103  1.00 24.32 ? 282 LEU   A HB2  1 
ATOM   4202  H  HB3  . LEU   A 1 283 ? 27.263  29.585  11.763  1.00 24.32 ? 282 LEU   A HB3  1 
ATOM   4203  H  HG   . LEU   A 1 283 ? 27.273  31.634  13.675  1.00 29.02 ? 282 LEU   A HG   1 
ATOM   4204  H  HD11 . LEU   A 1 283 ? 26.057  32.949  12.354  1.00 30.80 ? 282 LEU   A HD11 1 
ATOM   4205  H  HD12 . LEU   A 1 283 ? 27.262  32.430  11.458  1.00 30.80 ? 282 LEU   A HD12 1 
ATOM   4206  H  HD13 . LEU   A 1 283 ? 25.820  31.781  11.303  1.00 30.80 ? 282 LEU   A HD13 1 
ATOM   4207  H  HD21 . LEU   A 1 283 ? 24.809  31.187  13.463  1.00 35.58 ? 282 LEU   A HD21 1 
ATOM   4208  H  HD22 . LEU   A 1 283 ? 25.337  29.730  13.114  1.00 35.58 ? 282 LEU   A HD22 1 
ATOM   4209  H  HD23 . LEU   A 1 283 ? 25.689  30.387  14.516  1.00 35.58 ? 282 LEU   A HD23 1 
ATOM   4210  N  N    . TYR   A 1 284 ? 28.671  26.805  12.734  1.00 17.35 ? 283 TYR   A N    1 
ATOM   4211  C  CA   . TYR   A 1 284 ? 29.455  25.751  12.118  1.00 18.64 ? 283 TYR   A CA   1 
ATOM   4212  C  C    . TYR   A 1 284 ? 28.916  25.525  10.709  1.00 20.73 ? 283 TYR   A C    1 
ATOM   4213  O  O    . TYR   A 1 284 ? 27.701  25.505  10.491  1.00 21.43 ? 283 TYR   A O    1 
ATOM   4214  C  CB   . TYR   A 1 284 ? 29.347  24.437  12.853  1.00 19.92 ? 283 TYR   A CB   1 
ATOM   4215  C  CG   . TYR   A 1 284 ? 29.944  24.313  14.214  1.00 22.92 ? 283 TYR   A CG   1 
ATOM   4216  C  CD1  . TYR   A 1 284 ? 30.234  25.417  14.995  1.00 21.54 ? 283 TYR   A CD1  1 
ATOM   4217  C  CD2  . TYR   A 1 284 ? 30.140  23.054  14.747  1.00 29.62 ? 283 TYR   A CD2  1 
ATOM   4218  C  CE1  . TYR   A 1 284 ? 30.752  25.259  16.262  1.00 26.91 ? 283 TYR   A CE1  1 
ATOM   4219  C  CE2  . TYR   A 1 284 ? 30.630  22.882  16.030  1.00 29.40 ? 283 TYR   A CE2  1 
ATOM   4220  C  CZ   . TYR   A 1 284 ? 30.949  23.994  16.769  1.00 28.68 ? 283 TYR   A CZ   1 
ATOM   4221  O  OH   . TYR   A 1 284 ? 31.457  23.814  18.029  1.00 29.86 ? 283 TYR   A OH   1 
ATOM   4222  H  H    . TYR   A 1 284 ? 27.881  26.555  12.966  1.00 20.82 ? 283 TYR   A H    1 
ATOM   4223  H  HA   . TYR   A 1 284 ? 30.387  26.020  12.113  1.00 22.37 ? 283 TYR   A HA   1 
ATOM   4224  H  HB2  . TYR   A 1 284 ? 28.403  24.235  12.951  1.00 23.90 ? 283 TYR   A HB2  1 
ATOM   4225  H  HB3  . TYR   A 1 284 ? 29.775  23.761  12.305  1.00 23.90 ? 283 TYR   A HB3  1 
ATOM   4226  H  HD1  . TYR   A 1 284 ? 30.077  26.272  14.663  1.00 25.85 ? 283 TYR   A HD1  1 
ATOM   4227  H  HD2  . TYR   A 1 284 ? 29.937  22.306  14.233  1.00 35.54 ? 283 TYR   A HD2  1 
ATOM   4228  H  HE1  . TYR   A 1 284 ? 30.968  26.005  16.773  1.00 32.29 ? 283 TYR   A HE1  1 
ATOM   4229  H  HE2  . TYR   A 1 284 ? 30.740  22.029  16.385  1.00 35.28 ? 283 TYR   A HE2  1 
ATOM   4230  H  HH   . TYR   A 1 284 ? 30.852  23.927  18.601  1.00 35.84 ? 283 TYR   A HH   1 
ATOM   4231  N  N    . CYS   A 1 285 ? 29.800  25.367  9.759   1.00 17.37 ? 284 CYS   A N    1 
ATOM   4232  C  CA   . CYS   A 1 285 ? 29.414  24.893  8.431   1.00 17.11 ? 284 CYS   A CA   1 
ATOM   4233  C  C    . CYS   A 1 285 ? 30.051  23.520  8.272   1.00 20.50 ? 284 CYS   A C    1 
ATOM   4234  O  O    . CYS   A 1 285 ? 31.288  23.402  8.205   1.00 20.04 ? 284 CYS   A O    1 
ATOM   4235  C  CB   . CYS   A 1 285 ? 29.878  25.860  7.372   1.00 14.45 ? 284 CYS   A CB   1 
ATOM   4236  S  SG   . CYS   A 1 285 ? 29.538  25.245  5.694   1.00 23.99 ? 284 CYS   A SG   1 
ATOM   4237  H  H    . CYS   A 1 285 ? 30.641  25.526  9.847   1.00 20.84 ? 284 CYS   A H    1 
ATOM   4238  H  HA   . CYS   A 1 285 ? 28.451  24.810  8.346   1.00 20.53 ? 284 CYS   A HA   1 
ATOM   4239  H  HB2  . CYS   A 1 285 ? 29.414  26.704  7.486   1.00 17.33 ? 284 CYS   A HB2  1 
ATOM   4240  H  HB3  . CYS   A 1 285 ? 30.835  25.992  7.459   1.00 17.33 ? 284 CYS   A HB3  1 
ATOM   4241  H  HG   . CYS   A 1 285 ? 28.486  24.667  5.695   1.00 28.79 ? 284 CYS   A HG   1 
ATOM   4242  N  N    . ILE   A 1 286 ? 29.227  22.487  8.306   1.00 16.22 ? 285 ILE   A N    1 
ATOM   4243  C  CA   . ILE   A 1 286 ? 29.671  21.115  8.097   1.00 15.90 ? 285 ILE   A CA   1 
ATOM   4244  C  C    . ILE   A 1 286 ? 29.388  20.740  6.648   1.00 17.63 ? 285 ILE   A C    1 
ATOM   4245  O  O    . ILE   A 1 286 ? 28.235  20.745  6.206   1.00 18.26 ? 285 ILE   A O    1 
ATOM   4246  C  CB   . ILE   A 1 286 ? 28.992  20.134  9.054   1.00 19.00 ? 285 ILE   A CB   1 
ATOM   4247  C  CG1  . ILE   A 1 286 ? 29.179  20.615  10.493  1.00 20.92 ? 285 ILE   A CG1  1 
ATOM   4248  C  CG2  . ILE   A 1 286 ? 29.532  18.713  8.821   1.00 17.54 ? 285 ILE   A CG2  1 
ATOM   4249  C  CD1  . ILE   A 1 286 ? 28.453  19.794  11.478  1.00 18.79 ? 285 ILE   A CD1  1 
ATOM   4250  H  H    . ILE   A 1 286 ? 28.383  22.554  8.453   1.00 19.46 ? 285 ILE   A H    1 
ATOM   4251  H  HA   . ILE   A 1 286 ? 30.628  21.072  8.251   1.00 19.08 ? 285 ILE   A HA   1 
ATOM   4252  H  HB   . ILE   A 1 286 ? 28.038  20.103  8.883   1.00 22.80 ? 285 ILE   A HB   1 
ATOM   4253  H  HG12 . ILE   A 1 286 ? 30.123  20.582  10.715  1.00 25.11 ? 285 ILE   A HG12 1 
ATOM   4254  H  HG13 . ILE   A 1 286 ? 28.853  21.526  10.565  1.00 25.11 ? 285 ILE   A HG13 1 
ATOM   4255  H  HG21 . ILE   A 1 286 ? 29.128  18.112  9.466   1.00 21.05 ? 285 ILE   A HG21 1 
ATOM   4256  H  HG22 . ILE   A 1 286 ? 29.306  18.434  7.920   1.00 21.05 ? 285 ILE   A HG22 1 
ATOM   4257  H  HG23 . ILE   A 1 286 ? 30.495  18.719  8.933   1.00 21.05 ? 285 ILE   A HG23 1 
ATOM   4258  H  HD11 . ILE   A 1 286 ? 28.214  20.350  12.237  1.00 22.54 ? 285 ILE   A HD11 1 
ATOM   4259  H  HD12 . ILE   A 1 286 ? 27.652  19.438  11.063  1.00 22.54 ? 285 ILE   A HD12 1 
ATOM   4260  H  HD13 . ILE   A 1 286 ? 29.027  19.068  11.768  1.00 22.54 ? 285 ILE   A HD13 1 
ATOM   4261  N  N    . ASP   A 1 287 ? 30.443  20.380  5.933   1.00 15.97 ? 286 ASP   A N    1 
ATOM   4262  C  CA   . ASP   A 1 287 ? 30.410  20.120  4.478   1.00 18.72 ? 286 ASP   A CA   1 
ATOM   4263  C  C    . ASP   A 1 287 ? 30.981  18.722  4.334   1.00 15.54 ? 286 ASP   A C    1 
ATOM   4264  O  O    . ASP   A 1 287 ? 32.169  18.548  4.007   1.00 18.63 ? 286 ASP   A O    1 
ATOM   4265  C  CB   . ASP   A 1 287 ? 31.217  21.149  3.749   1.00 20.43 ? 286 ASP   A CB   1 
ATOM   4266  C  CG   . ASP   A 1 287 ? 31.161  20.990  2.242   1.00 25.06 ? 286 ASP   A CG   1 
ATOM   4267  O  OD1  . ASP   A 1 287 ? 30.401  20.156  1.728   1.00 21.41 ? 286 ASP   A OD1  1 
ATOM   4268  O  OD2  . ASP   A 1 287 ? 31.961  21.660  1.581   1.00 26.54 ? 286 ASP   A OD2  1 
ATOM   4269  H  H    . ASP   A 1 287 ? 31.226  20.272  6.272   1.00 19.16 ? 286 ASP   A H    1 
ATOM   4270  H  HA   . ASP   A 1 287 ? 29.509  20.150  4.120   1.00 22.46 ? 286 ASP   A HA   1 
ATOM   4271  H  HB2  . ASP   A 1 287 ? 30.876  22.030  3.969   1.00 24.51 ? 286 ASP   A HB2  1 
ATOM   4272  H  HB3  . ASP   A 1 287 ? 32.144  21.075  4.024   1.00 24.51 ? 286 ASP   A HB3  1 
ATOM   4273  N  N    . GLY   A 1 288 ? 30.146  17.723  4.593   1.00 17.51 ? 287 GLY   A N    1 
ATOM   4274  C  CA   . GLY   A 1 288 ? 30.586  16.353  4.641   1.00 18.11 ? 287 GLY   A CA   1 
ATOM   4275  C  C    . GLY   A 1 288 ? 31.643  16.139  5.701   1.00 20.14 ? 287 GLY   A C    1 
ATOM   4276  O  O    . GLY   A 1 288 ? 31.348  16.216  6.895   1.00 18.10 ? 287 GLY   A O    1 
ATOM   4277  H  H    . GLY   A 1 288 ? 29.306  17.823  4.747   1.00 21.01 ? 287 GLY   A H    1 
ATOM   4278  H  HA2  . GLY   A 1 288 ? 29.831  15.778  4.838   1.00 21.73 ? 287 GLY   A HA2  1 
ATOM   4279  H  HA3  . GLY   A 1 288 ? 30.958  16.103  3.781   1.00 21.73 ? 287 GLY   A HA3  1 
ATOM   4280  N  N    . ALA   A 1 289 ? 32.879  15.860  5.285   1.00 19.77 ? 288 ALA   A N    1 
ATOM   4281  C  CA   . ALA   A 1 289 ? 33.970  15.685  6.237   1.00 21.06 ? 288 ALA   A CA   1 
ATOM   4282  C  C    . ALA   A 1 289 ? 34.621  16.996  6.664   1.00 23.78 ? 288 ALA   A C    1 
ATOM   4283  O  O    . ALA   A 1 289 ? 35.446  16.978  7.587   1.00 30.98 ? 288 ALA   A O    1 
ATOM   4284  C  CB   . ALA   A 1 289 ? 35.040  14.765  5.637   1.00 26.63 ? 288 ALA   A CB   1 
ATOM   4285  H  H    . ALA   A 1 289 ? 33.108  15.770  4.461   1.00 23.72 ? 288 ALA   A H    1 
ATOM   4286  H  HA   . ALA   A 1 289 ? 33.612  15.262  7.034   1.00 25.28 ? 288 ALA   A HA   1 
ATOM   4287  H  HB1  . ALA   A 1 289 ? 35.539  14.349  6.357   1.00 31.96 ? 288 ALA   A HB1  1 
ATOM   4288  H  HB2  . ALA   A 1 289 ? 34.606  14.085  5.098   1.00 31.96 ? 288 ALA   A HB2  1 
ATOM   4289  H  HB3  . ALA   A 1 289 ? 35.636  15.294  5.083   1.00 31.96 ? 288 ALA   A HB3  1 
ATOM   4290  N  N    . LEU   A 1 290 ? 34.289  18.122  6.034   1.00 21.95 ? 289 LEU   A N    1 
ATOM   4291  C  CA   . LEU   A 1 290 ? 34.968  19.391  6.275   1.00 26.64 ? 289 LEU   A CA   1 
ATOM   4292  C  C    . LEU   A 1 290 ? 34.161  20.268  7.233   1.00 24.49 ? 289 LEU   A C    1 
ATOM   4293  O  O    . LEU   A 1 290 ? 32.949  20.430  7.082   1.00 22.30 ? 289 LEU   A O    1 
ATOM   4294  C  CB   . LEU   A 1 290 ? 35.152  20.157  4.962   1.00 24.38 ? 289 LEU   A CB   1 
ATOM   4295  C  CG   . LEU   A 1 290 ? 35.450  19.390  3.656   1.00 36.76 ? 289 LEU   A CG   1 
ATOM   4296  C  CD1  . LEU   A 1 290 ? 35.584  20.270  2.399   1.00 45.82 ? 289 LEU   A CD1  1 
ATOM   4297  C  CD2  . LEU   A 1 290 ? 36.701  18.523  3.762   1.00 41.97 ? 289 LEU   A CD2  1 
ATOM   4298  H  H    . LEU   A 1 290 ? 33.659  18.175  5.450   1.00 26.34 ? 289 LEU   A H    1 
ATOM   4299  H  HA   . LEU   A 1 290 ? 35.832  19.209  6.674   1.00 31.96 ? 289 LEU   A HA   1 
ATOM   4300  H  HB2  . LEU   A 1 290 ? 34.334  20.653  4.802   1.00 29.26 ? 289 LEU   A HB2  1 
ATOM   4301  H  HB3  . LEU   A 1 290 ? 35.892  20.770  5.089   1.00 29.26 ? 289 LEU   A HB3  1 
ATOM   4302  H  HG   . LEU   A 1 290 ? 34.665  18.832  3.537   1.00 44.12 ? 289 LEU   A HG   1 
ATOM   4303  H  HD11 . LEU   A 1 290 ? 35.680  19.698  1.622   1.00 54.98 ? 289 LEU   A HD11 1 
ATOM   4304  H  HD12 . LEU   A 1 290 ? 34.788  20.817  2.311   1.00 54.98 ? 289 LEU   A HD12 1 
ATOM   4305  H  HD13 . LEU   A 1 290 ? 36.366  20.836  2.492   1.00 54.98 ? 289 LEU   A HD13 1 
ATOM   4306  H  HD21 . LEU   A 1 290 ? 37.147  18.506  2.901   1.00 50.37 ? 289 LEU   A HD21 1 
ATOM   4307  H  HD22 . LEU   A 1 290 ? 37.291  18.900  4.433   1.00 50.37 ? 289 LEU   A HD22 1 
ATOM   4308  H  HD23 . LEU   A 1 290 ? 36.442  17.624  4.018   1.00 50.37 ? 289 LEU   A HD23 1 
ATOM   4309  N  N    . LEU   A 1 291 ? 34.849  20.909  8.166   1.00 26.39 ? 290 LEU   A N    1 
ATOM   4310  C  CA   . LEU   A 1 291 ? 34.219  21.783  9.146   1.00 24.59 ? 290 LEU   A CA   1 
ATOM   4311  C  C    . LEU   A 1 291 ? 34.884  23.152  9.047   1.00 25.61 ? 290 LEU   A C    1 
ATOM   4312  O  O    . LEU   A 1 291 ? 36.114  23.241  9.013   1.00 27.28 ? 290 LEU   A O    1 
ATOM   4313  C  CB   . LEU   A 1 291 ? 34.371  21.262  10.569  1.00 28.05 ? 290 LEU   A CB   1 
ATOM   4314  C  CG   . LEU   A 1 291 ? 33.859  22.214  11.651  1.00 28.58 ? 290 LEU   A CG   1 
ATOM   4315  C  CD1  . LEU   A 1 291 ? 32.359  22.491  11.529  1.00 26.97 ? 290 LEU   A CD1  1 
ATOM   4316  C  CD2  . LEU   A 1 291 ? 34.222  21.673  13.015  1.00 30.20 ? 290 LEU   A CD2  1 
ATOM   4317  H  H    . LEU   A 1 291 ? 35.703  20.852  8.254   1.00 31.66 ? 290 LEU   A H    1 
ATOM   4318  H  HA   . LEU   A 1 291 ? 33.271  21.849  8.952   1.00 29.50 ? 290 LEU   A HA   1 
ATOM   4319  H  HB2  . LEU   A 1 291 ? 33.874  20.433  10.648  1.00 33.66 ? 290 LEU   A HB2  1 
ATOM   4320  H  HB3  . LEU   A 1 291 ? 35.312  21.102  10.740  1.00 33.66 ? 290 LEU   A HB3  1 
ATOM   4321  H  HG   . LEU   A 1 291 ? 34.289  23.076  11.535  1.00 34.29 ? 290 LEU   A HG   1 
ATOM   4322  H  HD11 . LEU   A 1 291 ? 32.230  23.347  11.091  1.00 32.36 ? 290 LEU   A HD11 1 
ATOM   4323  H  HD12 . LEU   A 1 291 ? 31.949  21.786  11.004  1.00 32.36 ? 290 LEU   A HD12 1 
ATOM   4324  H  HD13 . LEU   A 1 291 ? 31.968  22.512  12.416  1.00 32.36 ? 290 LEU   A HD13 1 
ATOM   4325  H  HD21 . LEU   A 1 291 ? 33.780  22.206  13.694  1.00 36.24 ? 290 LEU   A HD21 1 
ATOM   4326  H  HD22 . LEU   A 1 291 ? 33.929  20.750  13.077  1.00 36.24 ? 290 LEU   A HD22 1 
ATOM   4327  H  HD23 . LEU   A 1 291 ? 35.184  21.723  13.128  1.00 36.24 ? 290 LEU   A HD23 1 
ATOM   4328  N  N    . THR   A 1 292 ? 34.084  24.201  8.959   1.00 20.85 ? 291 THR   A N    1 
ATOM   4329  C  CA   . THR   A 1 292 ? 34.565  25.558  9.154   1.00 19.95 ? 291 THR   A CA   1 
ATOM   4330  C  C    . THR   A 1 292 ? 33.648  26.292  10.123  1.00 22.89 ? 291 THR   A C    1 
ATOM   4331  O  O    . THR   A 1 292 ? 32.479  25.937  10.297  1.00 20.64 ? 291 THR   A O    1 
ATOM   4332  C  CB   . THR   A 1 292 ? 34.651  26.349  7.827   1.00 24.34 ? 291 THR   A CB   1 
ATOM   4333  O  OG1  . THR   A 1 292 ? 33.372  26.394  7.203   1.00 25.15 ? 291 THR   A OG1  1 
ATOM   4334  C  CG2  . THR   A 1 292 ? 35.641  25.699  6.913   1.00 28.30 ? 291 THR   A CG2  1 
ATOM   4335  H  H    . THR   A 1 292 ? 33.244  24.151  8.785   1.00 25.01 ? 291 THR   A H    1 
ATOM   4336  H  HA   . THR   A 1 292 ? 35.455  25.518  9.538   1.00 23.94 ? 291 THR   A HA   1 
ATOM   4337  H  HB   . THR   A 1 292 ? 34.941  27.258  8.002   1.00 29.21 ? 291 THR   A HB   1 
ATOM   4338  H  HG1  . THR   A 1 292 ? 33.118  25.616  7.013   1.00 30.18 ? 291 THR   A HG1  1 
ATOM   4339  H  HG21 . THR   A 1 292 ? 35.816  26.274  6.151   1.00 33.97 ? 291 THR   A HG21 1 
ATOM   4340  H  HG22 . THR   A 1 292 ? 36.473  25.540  7.385   1.00 33.97 ? 291 THR   A HG22 1 
ATOM   4341  H  HG23 . THR   A 1 292 ? 35.292  24.852  6.594   1.00 33.97 ? 291 THR   A HG23 1 
ATOM   4342  N  N    . LYS   A 1 293 ? 34.191  27.326  10.766  1.00 20.46 ? 292 LYS   A N    1 
ATOM   4343  C  CA   . LYS   A 1 293 ? 33.443  28.092  11.747  1.00 20.12 ? 292 LYS   A CA   1 
ATOM   4344  C  C    . LYS   A 1 293 ? 33.496  29.571  11.407  1.00 20.85 ? 292 LYS   A C    1 
ATOM   4345  O  O    . LYS   A 1 293 ? 34.500  30.066  10.888  1.00 21.77 ? 292 LYS   A O    1 
ATOM   4346  C  CB   . LYS   A 1 293 ? 34.014  27.882  13.163  1.00 22.71 ? 292 LYS   A CB   1 
ATOM   4347  C  CG   . LYS   A 1 293 ? 33.772  26.498  13.702  1.00 24.69 ? 292 LYS   A CG   1 
ATOM   4348  C  CD   . LYS   A 1 293 ? 34.258  26.360  15.150  1.00 23.94 ? 292 LYS   A CD   1 
ATOM   4349  C  CE   . LYS   A 1 293 ? 34.417  24.892  15.541  1.00 27.88 ? 292 LYS   A CE   1 
ATOM   4350  N  NZ   . LYS   A 1 293 ? 34.409  24.770  17.054  1.00 32.08 ? 292 LYS   A NZ   1 
ATOM   4351  H  H    . LYS   A 1 293 ? 34.997  27.601  10.646  1.00 24.55 ? 292 LYS   A H    1 
ATOM   4352  H  HA   . LYS   A 1 293 ? 32.515  27.810  11.731  1.00 24.14 ? 292 LYS   A HA   1 
ATOM   4353  H  HB2  . LYS   A 1 293 ? 34.972  28.031  13.140  1.00 27.25 ? 292 LYS   A HB2  1 
ATOM   4354  H  HB3  . LYS   A 1 293 ? 33.594  28.515  13.767  1.00 27.25 ? 292 LYS   A HB3  1 
ATOM   4355  H  HG2  . LYS   A 1 293 ? 32.821  26.307  13.681  1.00 29.63 ? 292 LYS   A HG2  1 
ATOM   4356  H  HG3  . LYS   A 1 293 ? 34.251  25.854  13.157  1.00 29.63 ? 292 LYS   A HG3  1 
ATOM   4357  H  HD2  . LYS   A 1 293 ? 35.119  26.797  15.244  1.00 28.73 ? 292 LYS   A HD2  1 
ATOM   4358  H  HD3  . LYS   A 1 293 ? 33.612  26.768  15.747  1.00 28.73 ? 292 LYS   A HD3  1 
ATOM   4359  H  HE2  . LYS   A 1 293 ? 33.680  24.374  15.181  1.00 33.46 ? 292 LYS   A HE2  1 
ATOM   4360  H  HE3  . LYS   A 1 293 ? 35.259  24.550  15.202  1.00 33.46 ? 292 LYS   A HE3  1 
ATOM   4361  H  HZ1  . LYS   A 1 293 ? 34.221  23.933  17.291  1.00 38.49 ? 292 LYS   A HZ1  1 
ATOM   4362  H  HZ2  . LYS   A 1 293 ? 35.207  24.990  17.381  1.00 38.49 ? 292 LYS   A HZ2  1 
ATOM   4363  H  HZ3  . LYS   A 1 293 ? 33.795  25.313  17.400  1.00 38.49 ? 292 LYS   A HZ3  1 
ATOM   4364  N  N    . SER   A 1 294 ? 32.425  30.287  11.744  1.00 20.34 ? 293 SER   A N    1 
ATOM   4365  C  CA   . SER   A 1 294 ? 32.409  31.728  11.564  1.00 21.34 ? 293 SER   A CA   1 
ATOM   4366  C  C    . SER   A 1 294 ? 31.393  32.345  12.514  1.00 26.46 ? 293 SER   A C    1 
ATOM   4367  O  O    . SER   A 1 294 ? 30.393  31.715  12.854  1.00 24.41 ? 293 SER   A O    1 
ATOM   4368  C  CB   . SER   A 1 294 ? 32.068  32.093  10.121  1.00 25.81 ? 293 SER   A CB   1 
ATOM   4369  O  OG   . SER   A 1 294 ? 30.774  31.578  9.799   1.00 30.78 ? 293 SER   A OG   1 
ATOM   4370  H  H    . SER   A 1 294 ? 31.702  29.960  12.076  1.00 24.41 ? 293 SER   A H    1 
ATOM   4371  H  HA   . SER   A 1 294 ? 33.282  32.088  11.784  1.00 25.61 ? 293 SER   A HA   1 
ATOM   4372  H  HB2  . SER   A 1 294 ? 32.064  33.058  10.026  1.00 30.97 ? 293 SER   A HB2  1 
ATOM   4373  H  HB3  . SER   A 1 294 ? 32.728  31.703  9.526   1.00 30.97 ? 293 SER   A HB3  1 
ATOM   4374  H  HG   . SER   A 1 294 ? 30.179  32.104  10.073  1.00 36.93 ? 293 SER   A HG   1 
ATOM   4375  N  N    . SER   A 1 295 ? 31.645  33.600  12.913  1.00 26.74 ? 294 SER   A N    1 
ATOM   4376  C  CA   . SER   A 1 295 ? 30.727  34.250  13.841  1.00 30.74 ? 294 SER   A CA   1 
ATOM   4377  C  C    . SER   A 1 295 ? 29.458  34.705  13.130  1.00 29.64 ? 294 SER   A C    1 
ATOM   4378  O  O    . SER   A 1 295 ? 28.421  34.873  13.782  1.00 30.27 ? 294 SER   A O    1 
ATOM   4379  C  CB   . SER   A 1 295 ? 31.379  35.449  14.535  1.00 32.97 ? 294 SER   A CB   1 
ATOM   4380  O  OG   . SER   A 1 295 ? 32.069  36.246  13.602  1.00 42.69 ? 294 SER   A OG   1 
ATOM   4381  H  H    . SER   A 1 295 ? 32.318  34.076  12.666  1.00 32.09 ? 294 SER   A H    1 
ATOM   4382  H  HA   . SER   A 1 295 ? 30.499  33.611  14.535  1.00 36.89 ? 294 SER   A HA   1 
ATOM   4383  H  HB2  . SER   A 1 295 ? 30.689  35.984  14.959  1.00 39.56 ? 294 SER   A HB2  1 
ATOM   4384  H  HB3  . SER   A 1 295 ? 32.005  35.127  15.202  1.00 39.56 ? 294 SER   A HB3  1 
ATOM   4385  H  HG   . SER   A 1 295 ? 31.525  36.607  13.074  1.00 51.23 ? 294 SER   A HG   1 
ATOM   4386  N  N    . GLU   A 1 296 ? 29.534  34.961  11.815  1.00 25.63 ? 295 GLU   A N    1 
ATOM   4387  C  CA   . GLU   A 1 296 ? 28.393  35.429  11.031  1.00 27.12 ? 295 GLU   A CA   1 
ATOM   4388  C  C    . GLU   A 1 296 ? 28.214  34.556  9.794   1.00 25.44 ? 295 GLU   A C    1 
ATOM   4389  O  O    . GLU   A 1 296 ? 29.111  33.811  9.412   1.00 24.12 ? 295 GLU   A O    1 
ATOM   4390  C  CB   . GLU   A 1 296 ? 28.544  36.893  10.592  1.00 29.67 ? 295 GLU   A CB   1 
ATOM   4391  C  CG   . GLU   A 1 296 ? 29.052  37.802  11.708  1.00 36.05 ? 295 GLU   A CG   1 
ATOM   4392  C  CD   . GLU   A 1 296 ? 27.937  38.382  12.564  1.00 52.95 ? 295 GLU   A CD   1 
ATOM   4393  O  OE1  . GLU   A 1 296 ? 26.806  37.826  12.564  1.00 47.35 ? 295 GLU   A OE1  1 
ATOM   4394  O  OE2  . GLU   A 1 296 ? 28.203  39.393  13.259  1.00 61.61 ? 295 GLU   A OE2  1 
ATOM   4395  H  H    . GLU   A 1 296 ? 30.252  34.867  11.351  1.00 30.76 ? 295 GLU   A H    1 
ATOM   4396  H  HA   . GLU   A 1 296 ? 27.599  35.355  11.583  1.00 32.54 ? 295 GLU   A HA   1 
ATOM   4397  H  HB2  . GLU   A 1 296 ? 29.176  36.938  9.858   1.00 35.61 ? 295 GLU   A HB2  1 
ATOM   4398  H  HB3  . GLU   A 1 296 ? 27.679  37.226  10.305  1.00 35.61 ? 295 GLU   A HB3  1 
ATOM   4399  H  HG2  . GLU   A 1 296 ? 29.638  37.291  12.288  1.00 43.26 ? 295 GLU   A HG2  1 
ATOM   4400  H  HG3  . GLU   A 1 296 ? 29.540  38.542  11.313  1.00 43.26 ? 295 GLU   A HG3  1 
ATOM   4401  N  N    . TYR   A 1 297 ? 27.030  34.645  9.181   1.00 22.64 ? 296 TYR   A N    1 
ATOM   4402  C  CA   . TYR   A 1 297 ? 26.735  33.849  7.992   1.00 22.97 ? 296 TYR   A CA   1 
ATOM   4403  C  C    . TYR   A 1 297 ? 25.722  34.556  7.097   1.00 23.87 ? 296 TYR   A C    1 
ATOM   4404  O  O    . TYR   A 1 297 ? 24.651  34.949  7.548   1.00 22.04 ? 296 TYR   A O    1 
ATOM   4405  C  CB   . TYR   A 1 297 ? 26.203  32.444  8.373   1.00 20.07 ? 296 TYR   A CB   1 
ATOM   4406  C  CG   . TYR   A 1 297 ? 25.851  31.651  7.147   1.00 24.64 ? 296 TYR   A CG   1 
ATOM   4407  C  CD1  . TYR   A 1 297 ? 24.608  31.807  6.529   1.00 18.89 ? 296 TYR   A CD1  1 
ATOM   4408  C  CD2  . TYR   A 1 297 ? 26.762  30.780  6.572   1.00 23.15 ? 296 TYR   A CD2  1 
ATOM   4409  C  CE1  . TYR   A 1 297 ? 24.296  31.131  5.370   1.00 21.72 ? 296 TYR   A CE1  1 
ATOM   4410  C  CE2  . TYR   A 1 297 ? 26.455  30.095  5.414   1.00 23.43 ? 296 TYR   A CE2  1 
ATOM   4411  C  CZ   . TYR   A 1 297 ? 25.217  30.268  4.818   1.00 23.48 ? 296 TYR   A CZ   1 
ATOM   4412  O  OH   . TYR   A 1 297 ? 24.906  29.601  3.650   1.00 24.37 ? 296 TYR   A OH   1 
ATOM   4413  H  H    . TYR   A 1 297 ? 26.387  35.157  9.434   1.00 27.17 ? 296 TYR   A H    1 
ATOM   4414  H  HA   . TYR   A 1 297 ? 27.558  33.758  7.486   1.00 27.57 ? 296 TYR   A HA   1 
ATOM   4415  H  HB2  . TYR   A 1 297 ? 26.887  31.963  8.865   1.00 24.09 ? 296 TYR   A HB2  1 
ATOM   4416  H  HB3  . TYR   A 1 297 ? 25.406  32.538  8.918   1.00 24.09 ? 296 TYR   A HB3  1 
ATOM   4417  H  HD1  . TYR   A 1 297 ? 23.979  32.378  6.907   1.00 22.67 ? 296 TYR   A HD1  1 
ATOM   4418  H  HD2  . TYR   A 1 297 ? 27.592  30.655  6.972   1.00 27.78 ? 296 TYR   A HD2  1 
ATOM   4419  H  HE1  . TYR   A 1 297 ? 23.469  31.257  4.964   1.00 26.06 ? 296 TYR   A HE1  1 
ATOM   4420  H  HE2  . TYR   A 1 297 ? 27.078  29.519  5.034   1.00 28.12 ? 296 TYR   A HE2  1 
ATOM   4421  H  HH   . TYR   A 1 297 ? 24.678  28.811  3.822   1.00 29.24 ? 296 TYR   A HH   1 
ATOM   4422  N  N    . LYS   A 1 298 ? 26.054  34.695  5.814   1.00 22.75 ? 297 LYS   A N    1 
ATOM   4423  C  CA   . LYS   A 1 298 ? 25.112  35.102  4.783   1.00 19.38 ? 297 LYS   A CA   1 
ATOM   4424  C  C    . LYS   A 1 298 ? 25.364  34.146  3.632   1.00 22.47 ? 297 LYS   A C    1 
ATOM   4425  O  O    . LYS   A 1 298 ? 26.520  33.925  3.267   1.00 23.40 ? 297 LYS   A O    1 
ATOM   4426  C  CB   . LYS   A 1 298 ? 25.298  36.566  4.347   1.00 26.32 ? 297 LYS   A CB   1 
ATOM   4427  C  CG   . LYS   A 1 298 ? 24.817  37.551  5.389   1.00 27.50 ? 297 LYS   A CG   1 
ATOM   4428  C  CD   . LYS   A 1 298 ? 24.759  38.993  4.894   1.00 29.54 ? 297 LYS   A CD   1 
ATOM   4429  C  CE   . LYS   A 1 298 ? 24.909  39.960  6.042   1.00 34.37 ? 297 LYS   A CE   1 
ATOM   4430  N  NZ   . LYS   A 1 298 ? 24.793  41.385  5.669   1.00 35.03 ? 297 LYS   A NZ   1 
ATOM   4431  H  H    . LYS   A 1 298 ? 26.846  34.554  5.510   1.00 27.30 ? 297 LYS   A H    1 
ATOM   4432  H  HA   . LYS   A 1 298 ? 24.194  35.046  5.092   1.00 23.26 ? 297 LYS   A HA   1 
ATOM   4433  H  HB2  . LYS   A 1 298 ? 26.240  36.732  4.188   1.00 31.58 ? 297 LYS   A HB2  1 
ATOM   4434  H  HB3  . LYS   A 1 298 ? 24.793  36.720  3.533   1.00 31.58 ? 297 LYS   A HB3  1 
ATOM   4435  H  HG2  . LYS   A 1 298 ? 23.923  37.299  5.669   1.00 33.00 ? 297 LYS   A HG2  1 
ATOM   4436  H  HG3  . LYS   A 1 298 ? 25.422  37.524  6.147   1.00 33.00 ? 297 LYS   A HG3  1 
ATOM   4437  H  HD2  . LYS   A 1 298 ? 25.480  39.149  4.264   1.00 35.45 ? 297 LYS   A HD2  1 
ATOM   4438  H  HD3  . LYS   A 1 298 ? 23.904  39.154  4.466   1.00 35.45 ? 297 LYS   A HD3  1 
ATOM   4439  H  HE2  . LYS   A 1 298 ? 24.218  39.773  6.696   1.00 41.25 ? 297 LYS   A HE2  1 
ATOM   4440  H  HE3  . LYS   A 1 298 ? 25.785  39.834  6.439   1.00 41.25 ? 297 LYS   A HE3  1 
ATOM   4441  H  HZ1  . LYS   A 1 298 ? 24.999  41.899  6.366   1.00 42.04 ? 297 LYS   A HZ1  1 
ATOM   4442  H  HZ2  . LYS   A 1 298 ? 25.348  41.570  4.999   1.00 42.04 ? 297 LYS   A HZ2  1 
ATOM   4443  H  HZ3  . LYS   A 1 298 ? 23.960  41.565  5.413   1.00 42.04 ? 297 LYS   A HZ3  1 
ATOM   4444  N  N    . GLY   A 1 299 ? 24.316  33.503  3.136   1.00 19.18 ? 298 GLY   A N    1 
ATOM   4445  C  CA   . GLY   A 1 299 ? 24.467  32.537  2.068   1.00 20.74 ? 298 GLY   A CA   1 
ATOM   4446  C  C    . GLY   A 1 299 ? 23.144  31.983  1.608   1.00 19.67 ? 298 GLY   A C    1 
ATOM   4447  O  O    . GLY   A 1 299 ? 22.085  32.310  2.161   1.00 18.98 ? 298 GLY   A O    1 
ATOM   4448  H  H    . GLY   A 1 299 ? 23.506  33.612  3.404   1.00 23.02 ? 298 GLY   A H    1 
ATOM   4449  H  HA2  . GLY   A 1 299 ? 24.901  32.960  1.311   1.00 24.89 ? 298 GLY   A HA2  1 
ATOM   4450  H  HA3  . GLY   A 1 299 ? 25.017  31.800  2.377   1.00 24.89 ? 298 GLY   A HA3  1 
ATOM   4451  N  N    . PRO   A 1 300 ? 23.173  31.131  0.543   1.00 17.90 ? 299 PRO   A N    1 
ATOM   4452  C  CA   . PRO   A 1 300 ? 21.927  30.592  -0.030  1.00 16.82 ? 299 PRO   A CA   1 
ATOM   4453  C  C    . PRO   A 1 300 ? 21.365  29.478  0.815   1.00 18.23 ? 299 PRO   A C    1 
ATOM   4454  O  O    . PRO   A 1 300 ? 21.902  28.344  0.819   1.00 17.76 ? 299 PRO   A O    1 
ATOM   4455  C  CB   . PRO   A 1 300 ? 22.362  30.115  -1.418  1.00 17.59 ? 299 PRO   A CB   1 
ATOM   4456  C  CG   . PRO   A 1 300 ? 23.810  29.746  -1.220  1.00 17.29 ? 299 PRO   A CG   1 
ATOM   4457  C  CD   . PRO   A 1 300 ? 24.365  30.665  -0.180  1.00 21.98 ? 299 PRO   A CD   1 
ATOM   4458  H  HA   . PRO   A 1 300 ? 21.260  31.290  -0.118  1.00 20.19 ? 299 PRO   A HA   1 
ATOM   4459  H  HB2  . PRO   A 1 300 ? 21.836  29.347  -1.691  1.00 21.11 ? 299 PRO   A HB2  1 
ATOM   4460  H  HB3  . PRO   A 1 300 ? 22.266  30.831  -2.065  1.00 21.11 ? 299 PRO   A HB3  1 
ATOM   4461  H  HG2  . PRO   A 1 300 ? 23.869  28.825  -0.924  1.00 20.75 ? 299 PRO   A HG2  1 
ATOM   4462  H  HG3  . PRO   A 1 300 ? 24.287  29.857  -2.058  1.00 20.75 ? 299 PRO   A HG3  1 
ATOM   4463  H  HD2  . PRO   A 1 300 ? 24.963  30.188  0.416   1.00 26.37 ? 299 PRO   A HD2  1 
ATOM   4464  H  HD3  . PRO   A 1 300 ? 24.831  31.409  -0.592  1.00 26.37 ? 299 PRO   A HD3  1 
ATOM   4465  N  N    . ILE   A 1 301 ? 20.261  29.736  1.518   1.00 16.55 ? 300 ILE   A N    1 
ATOM   4466  C  CA   . ILE   A 1 301 ? 19.638  28.789  2.437   1.00 13.05 ? 300 ILE   A CA   1 
ATOM   4467  C  C    . ILE   A 1 301 ? 18.318  28.344  1.833   1.00 15.32 ? 300 ILE   A C    1 
ATOM   4468  O  O    . ILE   A 1 301 ? 17.619  29.154  1.215   1.00 17.96 ? 300 ILE   A O    1 
ATOM   4469  C  CB   . ILE   A 1 301 ? 19.443  29.423  3.821   1.00 13.78 ? 300 ILE   A CB   1 
ATOM   4470  C  CG1  . ILE   A 1 301 ? 20.815  29.808  4.426   1.00 16.65 ? 300 ILE   A CG1  1 
ATOM   4471  C  CG2  . ILE   A 1 301 ? 18.623  28.464  4.765   1.00 15.28 ? 300 ILE   A CG2  1 
ATOM   4472  C  CD1  . ILE   A 1 301 ? 21.778  28.677  4.616   1.00 17.03 ? 300 ILE   A CD1  1 
ATOM   4473  H  H    . ILE   A 1 301 ? 19.840  30.485  1.477   1.00 19.86 ? 300 ILE   A H    1 
ATOM   4474  H  HA   . ILE   A 1 301 ? 20.197  28.003  2.543   1.00 15.66 ? 300 ILE   A HA   1 
ATOM   4475  H  HB   . ILE   A 1 301 ? 18.926  30.238  3.725   1.00 16.54 ? 300 ILE   A HB   1 
ATOM   4476  H  HG12 . ILE   A 1 301 ? 21.239  30.451  3.836   1.00 19.99 ? 300 ILE   A HG12 1 
ATOM   4477  H  HG13 . ILE   A 1 301 ? 20.663  30.207  5.296   1.00 19.99 ? 300 ILE   A HG13 1 
ATOM   4478  H  HG21 . ILE   A 1 301 ? 18.815  28.690  5.688   1.00 18.34 ? 300 ILE   A HG21 1 
ATOM   4479  H  HG22 . ILE   A 1 301 ? 17.677  28.578  4.586   1.00 18.34 ? 300 ILE   A HG22 1 
ATOM   4480  H  HG23 . ILE   A 1 301 ? 18.885  27.547  4.587   1.00 18.34 ? 300 ILE   A HG23 1 
ATOM   4481  H  HD11 . ILE   A 1 301 ? 22.415  28.918  5.307   1.00 20.43 ? 300 ILE   A HD11 1 
ATOM   4482  H  HD12 . ILE   A 1 301 ? 21.286  27.885  4.883   1.00 20.43 ? 300 ILE   A HD12 1 
ATOM   4483  H  HD13 . ILE   A 1 301 ? 22.242  28.513  3.780   1.00 20.43 ? 300 ILE   A HD13 1 
ATOM   4484  N  N    . THR   A 1 302 ? 17.965  27.067  2.030   1.00 14.88 ? 301 THR   A N    1 
ATOM   4485  C  CA   . THR   A 1 302 ? 16.699  26.536  1.545   1.00 15.89 ? 301 THR   A CA   1 
ATOM   4486  C  C    . THR   A 1 302 ? 15.858  25.828  2.627   1.00 14.91 ? 301 THR   A C    1 
ATOM   4487  O  O    . THR   A 1 302 ? 14.639  25.684  2.435   1.00 15.01 ? 301 THR   A O    1 
ATOM   4488  C  CB   . THR   A 1 302 ? 16.955  25.626  0.313   1.00 18.09 ? 301 THR   A CB   1 
ATOM   4489  O  OG1  . THR   A 1 302 ? 15.739  25.294  -0.315  1.00 16.83 ? 301 THR   A OG1  1 
ATOM   4490  C  CG2  . THR   A 1 302 ? 17.685  24.318  0.632   1.00 16.04 ? 301 THR   A CG2  1 
ATOM   4491  H  H    . THR   A 1 302 ? 18.449  26.491  2.445   1.00 17.85 ? 301 THR   A H    1 
ATOM   4492  H  HA   . THR   A 1 302 ? 16.131  27.255  1.226   1.00 19.06 ? 301 THR   A HA   1 
ATOM   4493  H  HB   . THR   A 1 302 ? 17.531  26.140  -0.275  1.00 21.71 ? 301 THR   A HB   1 
ATOM   4494  H  HG1  . THR   A 1 302 ? 15.462  25.944  -0.768  1.00 20.20 ? 301 THR   A HG1  1 
ATOM   4495  H  HG21 . THR   A 1 302 ? 18.089  23.959  -0.174  1.00 19.25 ? 301 THR   A HG21 1 
ATOM   4496  H  HG22 . THR   A 1 302 ? 18.382  24.478  1.288   1.00 19.25 ? 301 THR   A HG22 1 
ATOM   4497  H  HG23 . THR   A 1 302 ? 17.060  23.668  0.988   1.00 19.25 ? 301 THR   A HG23 1 
ATOM   4498  N  N    . ASP   A 1 303 ? 16.435  25.452  3.776   1.00 13.86 ? 302 ASP   A N    1 
ATOM   4499  C  CA   . ASP   A 1 303 ? 15.661  24.930  4.903   1.00 15.45 ? 302 ASP   A CA   1 
ATOM   4500  C  C    . ASP   A 1 303 ? 16.257  25.519  6.164   1.00 14.07 ? 302 ASP   A C    1 
ATOM   4501  O  O    . ASP   A 1 303 ? 17.489  25.602  6.270   1.00 14.42 ? 302 ASP   A O    1 
ATOM   4502  C  CB   . ASP   A 1 303 ? 15.718  23.395  5.045   1.00 14.71 ? 302 ASP   A CB   1 
ATOM   4503  C  CG   . ASP   A 1 303 ? 15.469  22.670  3.754   1.00 17.34 ? 302 ASP   A CG   1 
ATOM   4504  O  OD1  . ASP   A 1 303 ? 14.340  22.748  3.207   1.00 18.72 ? 302 ASP   A OD1  1 
ATOM   4505  O  OD2  . ASP   A 1 303 ? 16.397  21.973  3.316   1.00 18.19 ? 302 ASP   A OD2  1 
ATOM   4506  H  H    . ASP   A 1 303 ? 17.281  25.491  3.924   1.00 16.63 ? 302 ASP   A H    1 
ATOM   4507  H  HA   . ASP   A 1 303 ? 14.732  25.179  4.779   1.00 18.55 ? 302 ASP   A HA   1 
ATOM   4508  H  HB2  . ASP   A 1 303 ? 16.599  23.142  5.364   1.00 17.66 ? 302 ASP   A HB2  1 
ATOM   4509  H  HB3  . ASP   A 1 303 ? 15.042  23.113  5.680   1.00 17.66 ? 302 ASP   A HB3  1 
ATOM   4510  N  N    . VAL   A 1 304 ? 15.411  25.878  7.138   1.00 15.10 ? 303 VAL   A N    1 
ATOM   4511  C  CA   . VAL   A 1 304 ? 15.870  26.214  8.483   1.00 15.95 ? 303 VAL   A CA   1 
ATOM   4512  C  C    . VAL   A 1 304 ? 15.010  25.441  9.474   1.00 14.82 ? 303 VAL   A C    1 
ATOM   4513  O  O    . VAL   A 1 304 ? 13.778  25.418  9.351   1.00 16.01 ? 303 VAL   A O    1 
ATOM   4514  C  CB   . VAL   A 1 304 ? 15.803  27.727  8.784   1.00 15.33 ? 303 VAL   A CB   1 
ATOM   4515  C  CG1  . VAL   A 1 304 ? 16.407  28.007  10.157  1.00 15.04 ? 303 VAL   A CG1  1 
ATOM   4516  C  CG2  . VAL   A 1 304 ? 16.517  28.526  7.674   1.00 15.99 ? 303 VAL   A CG2  1 
ATOM   4517  H  H    . VAL   A 1 304 ? 14.558  25.933  7.038   1.00 18.13 ? 303 VAL   A H    1 
ATOM   4518  H  HA   . VAL   A 1 304 ? 16.796  25.940  8.575   1.00 19.14 ? 303 VAL   A HA   1 
ATOM   4519  H  HB   . VAL   A 1 304 ? 14.878  28.019  8.800   1.00 18.39 ? 303 VAL   A HB   1 
ATOM   4520  H  HG11 . VAL   A 1 304 ? 16.476  28.966  10.282  1.00 18.05 ? 303 VAL   A HG11 1 
ATOM   4521  H  HG12 . VAL   A 1 304 ? 15.833  27.625  10.838  1.00 18.05 ? 303 VAL   A HG12 1 
ATOM   4522  H  HG13 . VAL   A 1 304 ? 17.288  27.603  10.202  1.00 18.05 ? 303 VAL   A HG13 1 
ATOM   4523  H  HG21 . VAL   A 1 304 ? 16.620  29.446  7.964   1.00 19.18 ? 303 VAL   A HG21 1 
ATOM   4524  H  HG22 . VAL   A 1 304 ? 17.388  28.131  7.512   1.00 19.18 ? 303 VAL   A HG22 1 
ATOM   4525  H  HG23 . VAL   A 1 304 ? 15.982  28.492  6.866   1.00 19.18 ? 303 VAL   A HG23 1 
ATOM   4526  N  N    . PHE   A 1 305 ? 15.655  24.806  10.434  1.00 17.57 ? 304 PHE   A N    1 
ATOM   4527  C  CA   . PHE   A 1 305 ? 14.990  24.056  11.490  1.00 14.77 ? 304 PHE   A CA   1 
ATOM   4528  C  C    . PHE   A 1 305 ? 15.089  24.829  12.785  1.00 16.11 ? 304 PHE   A C    1 
ATOM   4529  O  O    . PHE   A 1 305 ? 16.141  25.384  13.115  1.00 16.80 ? 304 PHE   A O    1 
ATOM   4530  C  CB   . PHE   A 1 305 ? 15.612  22.676  11.667  1.00 16.96 ? 304 PHE   A CB   1 
ATOM   4531  C  CG   . PHE   A 1 305 ? 15.502  21.810  10.446  1.00 17.40 ? 304 PHE   A CG   1 
ATOM   4532  C  CD1  . PHE   A 1 305 ? 16.347  22.008  9.360   1.00 18.79 ? 304 PHE   A CD1  1 
ATOM   4533  C  CD2  . PHE   A 1 305 ? 14.525  20.835  10.364  1.00 21.85 ? 304 PHE   A CD2  1 
ATOM   4534  C  CE1  . PHE   A 1 305 ? 16.224  21.209  8.204   1.00 20.52 ? 304 PHE   A CE1  1 
ATOM   4535  C  CE2  . PHE   A 1 305 ? 14.390  20.057  9.211   1.00 19.19 ? 304 PHE   A CE2  1 
ATOM   4536  C  CZ   . PHE   A 1 305 ? 15.245  20.246  8.137   1.00 19.80 ? 304 PHE   A CZ   1 
ATOM   4537  H  H    . PHE   A 1 305 ? 16.512  24.793  10.502  1.00 21.08 ? 304 PHE   A H    1 
ATOM   4538  H  HA   . PHE   A 1 305 ? 14.055  23.933  11.265  1.00 17.72 ? 304 PHE   A HA   1 
ATOM   4539  H  HB2  . PHE   A 1 305 ? 16.554  22.781  11.873  1.00 20.35 ? 304 PHE   A HB2  1 
ATOM   4540  H  HB3  . PHE   A 1 305 ? 15.162  22.221  12.396  1.00 20.35 ? 304 PHE   A HB3  1 
ATOM   4541  H  HD1  . PHE   A 1 305 ? 16.998  22.672  9.396   1.00 22.55 ? 304 PHE   A HD1  1 
ATOM   4542  H  HD2  . PHE   A 1 305 ? 13.953  20.695  11.084  1.00 26.22 ? 304 PHE   A HD2  1 
ATOM   4543  H  HE1  . PHE   A 1 305 ? 16.804  21.333  7.489   1.00 24.62 ? 304 PHE   A HE1  1 
ATOM   4544  H  HE2  . PHE   A 1 305 ? 13.724  19.410  9.164   1.00 23.03 ? 304 PHE   A HE2  1 
ATOM   4545  H  HZ   . PHE   A 1 305 ? 15.157  19.723  7.373   1.00 23.76 ? 304 PHE   A HZ   1 
ATOM   4546  N  N    . TYR   A 1 306 ? 14.001  24.828  13.526  1.00 17.05 ? 305 TYR   A N    1 
ATOM   4547  C  CA   . TYR   A 1 306 ? 13.947  25.494  14.812  1.00 16.34 ? 305 TYR   A CA   1 
ATOM   4548  C  C    . TYR   A 1 306 ? 13.348  24.536  15.833  1.00 19.16 ? 305 TYR   A C    1 
ATOM   4549  O  O    . TYR   A 1 306 ? 12.315  23.929  15.583  1.00 16.67 ? 305 TYR   A O    1 
ATOM   4550  C  CB   . TYR   A 1 306 ? 13.081  26.744  14.719  1.00 17.38 ? 305 TYR   A CB   1 
ATOM   4551  C  CG   . TYR   A 1 306 ? 13.386  27.741  13.640  1.00 15.42 ? 305 TYR   A CG   1 
ATOM   4552  C  CD1  . TYR   A 1 306 ? 12.977  27.523  12.314  1.00 14.28 ? 305 TYR   A CD1  1 
ATOM   4553  C  CD2  . TYR   A 1 306 ? 14.044  28.915  13.938  1.00 16.93 ? 305 TYR   A CD2  1 
ATOM   4554  C  CE1  . TYR   A 1 306 ? 13.211  28.452  11.344  1.00 16.43 ? 305 TYR   A CE1  1 
ATOM   4555  C  CE2  . TYR   A 1 306 ? 14.300  29.875  12.956  1.00 17.34 ? 305 TYR   A CE2  1 
ATOM   4556  C  CZ   . TYR   A 1 306 ? 13.887  29.629  11.664  1.00 16.84 ? 305 TYR   A CZ   1 
ATOM   4557  O  OH   . TYR   A 1 306 ? 14.152  30.585  10.726  1.00 18.48 ? 305 TYR   A OH   1 
ATOM   4558  H  H    . TYR   A 1 306 ? 13.266  24.442  13.302  1.00 20.46 ? 305 TYR   A H    1 
ATOM   4559  H  HA   . TYR   A 1 306 ? 14.840  25.741  15.100  1.00 19.61 ? 305 TYR   A HA   1 
ATOM   4560  H  HB2  . TYR   A 1 306 ? 12.165  26.458  14.581  1.00 20.86 ? 305 TYR   A HB2  1 
ATOM   4561  H  HB3  . TYR   A 1 306 ? 13.157  27.217  15.563  1.00 20.86 ? 305 TYR   A HB3  1 
ATOM   4562  H  HD1  . TYR   A 1 306 ? 12.540  26.733  12.094  1.00 17.13 ? 305 TYR   A HD1  1 
ATOM   4563  H  HD2  . TYR   A 1 306 ? 14.324  29.071  14.812  1.00 20.32 ? 305 TYR   A HD2  1 
ATOM   4564  H  HE1  . TYR   A 1 306 ? 12.922  28.302  10.473  1.00 19.71 ? 305 TYR   A HE1  1 
ATOM   4565  H  HE2  . TYR   A 1 306 ? 14.741  30.666  13.170  1.00 20.80 ? 305 TYR   A HE2  1 
ATOM   4566  H  HH   . TYR   A 1 306 ? 14.218  30.232  9.967   1.00 22.18 ? 305 TYR   A HH   1 
ATOM   4567  N  N    . LYS   A 1 307 ? 13.998  24.372  16.974  1.00 18.85 ? 306 LYS   A N    1 
ATOM   4568  C  CA   . LYS   A 1 307 ? 13.358  23.614  18.046  1.00 20.17 ? 306 LYS   A CA   1 
ATOM   4569  C  C    . LYS   A 1 307 ? 12.160  24.362  18.620  1.00 16.96 ? 306 LYS   A C    1 
ATOM   4570  O  O    . LYS   A 1 307 ? 12.011  25.573  18.494  1.00 17.97 ? 306 LYS   A O    1 
ATOM   4571  C  CB   . LYS   A 1 307 ? 14.393  23.294  19.118  1.00 23.05 ? 306 LYS   A CB   1 
ATOM   4572  C  CG   . LYS   A 1 307 ? 13.957  22.300  20.211  1.00 32.21 ? 306 LYS   A CG   1 
ATOM   4573  C  CD   . LYS   A 1 307 ? 15.198  21.733  20.946  1.00 35.58 ? 306 LYS   A CD   1 
ATOM   4574  C  CE   . LYS   A 1 307 ? 14.827  21.046  22.275  1.00 41.61 ? 306 LYS   A CE   1 
ATOM   4575  N  NZ   . LYS   A 1 307 ? 15.979  20.870  23.191  1.00 36.62 ? 306 LYS   A NZ   1 
ATOM   4576  H  H    . LYS   A 1 307 ? 14.782  24.678  17.150  1.00 22.62 ? 306 LYS   A H    1 
ATOM   4577  H  HA   . LYS   A 1 307 ? 13.009  22.775  17.706  1.00 24.21 ? 306 LYS   A HA   1 
ATOM   4578  H  HB2  . LYS   A 1 307 ? 15.172  22.915  18.681  1.00 27.66 ? 306 LYS   A HB2  1 
ATOM   4579  H  HB3  . LYS   A 1 307 ? 14.633  24.121  19.563  1.00 27.66 ? 306 LYS   A HB3  1 
ATOM   4580  H  HG2  . LYS   A 1 307 ? 13.393  22.752  20.858  1.00 38.65 ? 306 LYS   A HG2  1 
ATOM   4581  H  HG3  . LYS   A 1 307 ? 13.472  21.563  19.807  1.00 38.65 ? 306 LYS   A HG3  1 
ATOM   4582  H  HD2  . LYS   A 1 307 ? 15.633  21.078  20.378  1.00 42.70 ? 306 LYS   A HD2  1 
ATOM   4583  H  HD3  . LYS   A 1 307 ? 15.811  22.459  21.142  1.00 42.70 ? 306 LYS   A HD3  1 
ATOM   4584  H  HE2  . LYS   A 1 307 ? 14.164  21.586  22.733  1.00 49.93 ? 306 LYS   A HE2  1 
ATOM   4585  H  HE3  . LYS   A 1 307 ? 14.464  20.167  22.083  1.00 49.93 ? 306 LYS   A HE3  1 
ATOM   4586  H  HZ1  . LYS   A 1 307 ? 16.144  20.004  23.310  1.00 43.94 ? 306 LYS   A HZ1  1 
ATOM   4587  H  HZ2  . LYS   A 1 307 ? 16.703  21.257  22.847  1.00 43.94 ? 306 LYS   A HZ2  1 
ATOM   4588  H  HZ3  . LYS   A 1 307 ? 15.800  21.241  23.980  1.00 43.94 ? 306 LYS   A HZ3  1 
ATOM   4589  N  N    . GLU   A 1 308 ? 11.240  23.601  19.189  1.00 19.41 ? 307 GLU   A N    1 
ATOM   4590  C  CA   . GLU   A 1 308 ? 10.000  24.171  19.687  1.00 19.28 ? 307 GLU   A CA   1 
ATOM   4591  C  C    . GLU   A 1 308 ? 9.483   23.276  20.802  1.00 16.16 ? 307 GLU   A C    1 
ATOM   4592  O  O    . GLU   A 1 308 ? 9.954   22.145  21.000  1.00 19.66 ? 307 GLU   A O    1 
ATOM   4593  C  CB   . GLU   A 1 308 ? 8.986   24.313  18.538  1.00 21.92 ? 307 GLU   A CB   1 
ATOM   4594  C  CG   . GLU   A 1 308 ? 7.672   25.014  18.901  1.00 20.90 ? 307 GLU   A CG   1 
ATOM   4595  C  CD   . GLU   A 1 308 ? 7.842   26.376  19.563  1.00 23.91 ? 307 GLU   A CD   1 
ATOM   4596  O  OE1  . GLU   A 1 308 ? 7.935   26.443  20.833  1.00 22.95 ? 307 GLU   A OE1  1 
ATOM   4597  O  OE2  . GLU   A 1 308 ? 7.865   27.391  18.828  1.00 24.09 ? 307 GLU   A OE2  1 
ATOM   4598  H  H    . GLU   A 1 308 ? 11.310  22.751  19.298  1.00 23.29 ? 307 GLU   A H    1 
ATOM   4599  H  HA   . GLU   A 1 308 ? 10.148  25.051  20.067  1.00 23.13 ? 307 GLU   A HA   1 
ATOM   4600  H  HB2  . GLU   A 1 308 ? 9.400   24.827  17.827  1.00 26.30 ? 307 GLU   A HB2  1 
ATOM   4601  H  HB3  . GLU   A 1 308 ? 8.761   23.425  18.217  1.00 26.30 ? 307 GLU   A HB3  1 
ATOM   4602  H  HG2  . GLU   A 1 308 ? 7.157   25.146  18.089  1.00 25.08 ? 307 GLU   A HG2  1 
ATOM   4603  H  HG3  . GLU   A 1 308 ? 7.180   24.449  19.517  1.00 25.08 ? 307 GLU   A HG3  1 
ATOM   4604  N  N    . ASN   A 1 309 ? 8.511   23.802  21.543  1.00 20.40 ? 308 ASN   A N    1 
ATOM   4605  C  CA   . ASN   A 1 309 ? 7.678   22.914  22.330  1.00 19.11 ? 308 ASN   A CA   1 
ATOM   4606  C  C    . ASN   A 1 309 ? 6.241   23.395  22.236  1.00 18.04 ? 308 ASN   A C    1 
ATOM   4607  O  O    . ASN   A 1 309 ? 5.398   22.696  21.675  1.00 20.73 ? 308 ASN   A O    1 
ATOM   4608  C  CB   . ASN   A 1 309 ? 8.139   22.808  23.780  1.00 25.18 ? 308 ASN   A CB   1 
ATOM   4609  C  CG   . ASN   A 1 309 ? 7.299   21.785  24.564  1.00 24.93 ? 308 ASN   A CG   1 
ATOM   4610  O  OD1  . ASN   A 1 309 ? 6.255   22.130  25.124  1.00 28.29 ? 308 ASN   A OD1  1 
ATOM   4611  N  ND2  . ASN   A 1 309 ? 7.677   20.523  24.486  1.00 29.00 ? 308 ASN   A ND2  1 
ATOM   4612  H  H    . ASN   A 1 309 ? 8.324   24.639  21.601  1.00 24.47 ? 308 ASN   A H    1 
ATOM   4613  H  HA   . ASN   A 1 309 ? 7.744   22.012  21.980  1.00 22.93 ? 308 ASN   A HA   1 
ATOM   4614  H  HB2  . ASN   A 1 309 ? 9.066   22.523  23.802  1.00 30.21 ? 308 ASN   A HB2  1 
ATOM   4615  H  HB3  . ASN   A 1 309 ? 8.047   23.673  24.210  1.00 30.21 ? 308 ASN   A HB3  1 
ATOM   4616  H  HD21 . ASN   A 1 309 ? 7.238   19.916  24.908  1.00 34.80 ? 308 ASN   A HD21 1 
ATOM   4617  H  HD22 . ASN   A 1 309 ? 8.363   20.308  24.014  1.00 34.80 ? 308 ASN   A HD22 1 
ATOM   4618  N  N    . SER   A 1 310 ? 5.974   24.601  22.733  1.00 17.66 ? 309 SER   A N    1 
ATOM   4619  C  CA   . SER   A 1 310 ? 4.648   25.207  22.652  1.00 21.08 ? 309 SER   A CA   1 
ATOM   4620  C  C    . SER   A 1 310 ? 4.755   26.700  22.431  1.00 21.43 ? 309 SER   A C    1 
ATOM   4621  O  O    . SER   A 1 310 ? 5.383   27.403  23.225  1.00 23.20 ? 309 SER   A O    1 
ATOM   4622  C  CB   . SER   A 1 310 ? 3.844   24.929  23.929  1.00 26.97 ? 309 SER   A CB   1 
ATOM   4623  O  OG   . SER   A 1 310 ? 2.527   25.431  23.800  1.00 22.73 ? 309 SER   A OG   1 
ATOM   4624  H  H    . SER   A 1 310 ? 6.555   25.096  23.129  1.00 21.19 ? 309 SER   A H    1 
ATOM   4625  H  HA   . SER   A 1 310 ? 4.192   24.830  21.884  1.00 25.29 ? 309 SER   A HA   1 
ATOM   4626  H  HB2  . SER   A 1 310 ? 3.806   23.972  24.080  1.00 32.37 ? 309 SER   A HB2  1 
ATOM   4627  H  HB3  . SER   A 1 310 ? 4.277   25.366  24.679  1.00 32.37 ? 309 SER   A HB3  1 
ATOM   4628  H  HG   . SER   A 1 310 ? 2.219   25.237  23.042  1.00 27.28 ? 309 SER   A HG   1 
ATOM   4629  N  N    . TYR   A 1 311 ? 4.153   27.173  21.347  1.00 20.54 ? 310 TYR   A N    1 
ATOM   4630  C  CA   . TYR   A 1 311 ? 4.071   28.585  21.020  1.00 23.43 ? 310 TYR   A CA   1 
ATOM   4631  C  C    . TYR   A 1 311 ? 2.603   28.990  20.916  1.00 21.43 ? 310 TYR   A C    1 
ATOM   4632  O  O    . TYR   A 1 311 ? 1.796   28.316  20.248  1.00 20.39 ? 310 TYR   A O    1 
ATOM   4633  C  CB   . TYR   A 1 311 ? 4.785   28.901  19.693  1.00 21.89 ? 310 TYR   A CB   1 
ATOM   4634  C  CG   . TYR   A 1 311 ? 4.489   30.289  19.168  1.00 18.90 ? 310 TYR   A CG   1 
ATOM   4635  C  CD1  . TYR   A 1 311 ? 5.117   31.409  19.722  1.00 21.78 ? 310 TYR   A CD1  1 
ATOM   4636  C  CD2  . TYR   A 1 311 ? 3.564   30.494  18.148  1.00 18.83 ? 310 TYR   A CD2  1 
ATOM   4637  C  CE1  . TYR   A 1 311 ? 4.846   32.666  19.277  1.00 23.81 ? 310 TYR   A CE1  1 
ATOM   4638  C  CE2  . TYR   A 1 311 ? 3.280   31.743  17.696  1.00 21.03 ? 310 TYR   A CE2  1 
ATOM   4639  C  CZ   . TYR   A 1 311 ? 3.914   32.850  18.275  1.00 22.09 ? 310 TYR   A CZ   1 
ATOM   4640  O  OH   . TYR   A 1 311 ? 3.638   34.113  17.802  1.00 23.21 ? 310 TYR   A OH   1 
ATOM   4641  H  H    . TYR   A 1 311 ? 3.768   26.673  20.763  1.00 24.65 ? 310 TYR   A H    1 
ATOM   4642  H  HA   . TYR   A 1 311 ? 4.493   29.099  21.726  1.00 28.11 ? 310 TYR   A HA   1 
ATOM   4643  H  HB2  . TYR   A 1 311 ? 5.743   28.832  19.828  1.00 26.27 ? 310 TYR   A HB2  1 
ATOM   4644  H  HB3  . TYR   A 1 311 ? 4.497   28.261  19.022  1.00 26.27 ? 310 TYR   A HB3  1 
ATOM   4645  H  HD1  . TYR   A 1 311 ? 5.733   31.292  20.409  1.00 26.14 ? 310 TYR   A HD1  1 
ATOM   4646  H  HD2  . TYR   A 1 311 ? 3.132   29.763  17.769  1.00 22.59 ? 310 TYR   A HD2  1 
ATOM   4647  H  HE1  . TYR   A 1 311 ? 5.286   33.397  19.646  1.00 28.57 ? 310 TYR   A HE1  1 
ATOM   4648  H  HE2  . TYR   A 1 311 ? 2.667   31.863  17.007  1.00 25.24 ? 310 TYR   A HE2  1 
ATOM   4649  H  HH   . TYR   A 1 311 ? 3.542   34.092  16.968  1.00 27.85 ? 310 TYR   A HH   1 
ATOM   4650  N  N    . THR   A 1 312 ? 2.264   30.121  21.527  1.00 20.19 ? 311 THR   A N    1 
ATOM   4651  C  CA   . THR   A 1 312 ? 0.936   30.715  21.394  1.00 19.36 ? 311 THR   A CA   1 
ATOM   4652  C  C    . THR   A 1 312 ? 1.102   32.194  21.084  1.00 26.66 ? 311 THR   A C    1 
ATOM   4653  O  O    . THR   A 1 312 ? 1.840   32.897  21.784  1.00 25.69 ? 311 THR   A O    1 
ATOM   4654  C  CB   . THR   A 1 312 ? 0.080   30.521  22.662  1.00 27.51 ? 311 THR   A CB   1 
ATOM   4655  O  OG1  . THR   A 1 312 ? 0.027   29.136  23.022  1.00 27.10 ? 311 THR   A OG1  1 
ATOM   4656  C  CG2  . THR   A 1 312 ? -1.341  31.014  22.421  1.00 29.31 ? 311 THR   A CG2  1 
ATOM   4657  H  H    . THR   A 1 312 ? 2.795   30.570  22.033  1.00 24.23 ? 311 THR   A H    1 
ATOM   4658  H  HA   . THR   A 1 312 ? 0.464   30.288  20.662  1.00 23.24 ? 311 THR   A HA   1 
ATOM   4659  H  HB   . THR   A 1 312 ? 0.477   31.028  23.388  1.00 33.02 ? 311 THR   A HB   1 
ATOM   4660  H  HG1  . THR   A 1 312 ? -0.769  28.869  23.020  1.00 32.53 ? 311 THR   A HG1  1 
ATOM   4661  H  HG21 . THR   A 1 312 ? -1.938  30.644  23.090  1.00 35.17 ? 311 THR   A HG21 1 
ATOM   4662  H  HG22 . THR   A 1 312 ? -1.370  31.982  22.474  1.00 35.17 ? 311 THR   A HG22 1 
ATOM   4663  H  HG23 . THR   A 1 312 ? -1.644  30.737  21.542  1.00 35.17 ? 311 THR   A HG23 1 
ATOM   4664  N  N    . THR   A 1 313 ? 0.425   32.662  20.036  1.00 22.46 ? 312 THR   A N    1 
ATOM   4665  C  CA   . THR   A 1 313 ? 0.577   34.043  19.591  1.00 25.45 ? 312 THR   A CA   1 
ATOM   4666  C  C    . THR   A 1 313 ? 0.029   35.004  20.648  1.00 33.84 ? 312 THR   A C    1 
ATOM   4667  O  O    . THR   A 1 313 ? -0.813  34.649  21.478  1.00 29.58 ? 312 THR   A O    1 
ATOM   4668  C  CB   . THR   A 1 313 ? -0.152  34.261  18.267  1.00 30.09 ? 312 THR   A CB   1 
ATOM   4669  O  OG1  . THR   A 1 313 ? 0.115   35.569  17.738  1.00 30.42 ? 312 THR   A OG1  1 
ATOM   4670  C  CG2  . THR   A 1 313 ? -1.673  34.088  18.460  1.00 27.80 ? 312 THR   A CG2  1 
ATOM   4671  H  H    . THR   A 1 313 ? -0.128  32.199  19.567  1.00 26.95 ? 312 THR   A H    1 
ATOM   4672  H  HA   . THR   A 1 313 ? 1.518   34.237  19.454  1.00 30.55 ? 312 THR   A HA   1 
ATOM   4673  H  HB   . THR   A 1 313 ? 0.163   33.603  17.627  1.00 36.10 ? 312 THR   A HB   1 
ATOM   4674  H  HG1  . THR   A 1 313 ? -0.394  35.726  17.089  1.00 36.51 ? 312 THR   A HG1  1 
ATOM   4675  H  HG21 . THR   A 1 313 ? -2.091  33.867  17.613  1.00 33.36 ? 312 THR   A HG21 1 
ATOM   4676  H  HG22 . THR   A 1 313 ? -1.848  33.374  19.093  1.00 33.36 ? 312 THR   A HG22 1 
ATOM   4677  H  HG23 . THR   A 1 313 ? -2.060  34.911  18.797  1.00 33.36 ? 312 THR   A HG23 1 
ATOM   4678  N  N    . THR   A 1 314 ? 0.511   36.240  20.598  1.00 36.47 ? 313 THR   A N    1 
ATOM   4679  C  CA   . THR   A 1 314 ? -0.115  37.335  21.325  1.00 40.04 ? 313 THR   A CA   1 
ATOM   4680  C  C    . THR   A 1 314 ? -0.978  38.217  20.432  1.00 42.51 ? 313 THR   A C    1 
ATOM   4681  O  O    . THR   A 1 314 ? -1.599  39.155  20.936  1.00 47.72 ? 313 THR   A O    1 
ATOM   4682  C  CB   . THR   A 1 314 ? 0.947   38.206  22.004  1.00 39.64 ? 313 THR   A CB   1 
ATOM   4683  O  OG1  . THR   A 1 314 ? 1.711   38.883  21.003  1.00 47.20 ? 313 THR   A OG1  1 
ATOM   4684  C  CG2  . THR   A 1 314 ? 1.877   37.371  22.856  1.00 41.49 ? 313 THR   A CG2  1 
ATOM   4685  H  H    . THR   A 1 314 ? 1.205   36.470  20.145  1.00 43.77 ? 313 THR   A H    1 
ATOM   4686  H  HA   . THR   A 1 314 ? -0.678  36.954  22.017  1.00 48.04 ? 313 THR   A HA   1 
ATOM   4687  H  HB   . THR   A 1 314 ? 0.509   38.850  22.582  1.00 47.57 ? 313 THR   A HB   1 
ATOM   4688  H  HG1  . THR   A 1 314 ? 2.394   38.433  20.809  1.00 56.63 ? 313 THR   A HG1  1 
ATOM   4689  H  HG21 . THR   A 1 314 ? 2.327   37.934  23.505  1.00 49.79 ? 313 THR   A HG21 1 
ATOM   4690  H  HG22 . THR   A 1 314 ? 1.373   36.689  23.327  1.00 49.79 ? 313 THR   A HG22 1 
ATOM   4691  H  HG23 . THR   A 1 314 ? 2.542   36.941  22.297  1.00 49.79 ? 313 THR   A HG23 1 
ATOM   4692  N  N    . ILE   A 1 315 ? -1.038  37.947  19.128  1.00 36.60 ? 314 ILE   A N    1 
ATOM   4693  C  CA   . ILE   A 1 315 ? -1.917  38.688  18.230  1.00 41.55 ? 314 ILE   A CA   1 
ATOM   4694  C  C    . ILE   A 1 315 ? -3.384  38.418  18.548  1.00 47.81 ? 314 ILE   A C    1 
ATOM   4695  O  O    . ILE   A 1 315 ? -3.805  37.264  18.629  1.00 42.59 ? 314 ILE   A O    1 
ATOM   4696  C  CB   . ILE   A 1 315 ? -1.617  38.356  16.749  1.00 36.22 ? 314 ILE   A CB   1 
ATOM   4697  C  CG1  . ILE   A 1 315 ? -0.149  38.658  16.420  1.00 35.01 ? 314 ILE   A CG1  1 
ATOM   4698  C  CG2  . ILE   A 1 315 ? -2.600  39.052  15.825  1.00 42.58 ? 314 ILE   A CG2  1 
ATOM   4699  C  CD1  . ILE   A 1 315 ? 0.276   38.266  14.989  1.00 40.13 ? 314 ILE   A CD1  1 
ATOM   4700  N  N    . GLY   B 1 1   ? 17.157  74.580  19.585  1.00 26.19 ? 0   GLY   B N    1 
ATOM   4701  C  CA   . GLY   B 1 1   ? 15.789  74.394  20.022  1.00 25.40 ? 0   GLY   B CA   1 
ATOM   4702  C  C    . GLY   B 1 1   ? 15.698  74.265  21.550  1.00 27.45 ? 0   GLY   B C    1 
ATOM   4703  O  O    . GLY   B 1 1   ? 16.654  74.497  22.257  1.00 27.07 ? 0   GLY   B O    1 
ATOM   4704  N  N    . GLU   B 1 2   ? 14.508  73.896  22.000  1.00 27.41 ? 1   GLU   B N    1 
ATOM   4705  C  CA   . GLU   B 1 2   ? 14.180  73.762  23.413  1.00 34.14 ? 1   GLU   B CA   1 
ATOM   4706  C  C    . GLU   B 1 2   ? 15.110  72.747  24.076  1.00 31.85 ? 1   GLU   B C    1 
ATOM   4707  O  O    . GLU   B 1 2   ? 15.394  71.686  23.512  1.00 32.13 ? 1   GLU   B O    1 
ATOM   4708  C  CB   . GLU   B 1 2   ? 12.742  73.266  23.452  1.00 43.57 ? 1   GLU   B CB   1 
ATOM   4709  C  CG   . GLU   B 1 2   ? 11.669  74.155  23.968  1.00 47.55 ? 1   GLU   B CG   1 
ATOM   4710  C  CD   . GLU   B 1 2   ? 10.496  73.322  24.447  1.00 56.86 ? 1   GLU   B CD   1 
ATOM   4711  O  OE1  . GLU   B 1 2   ? 9.861   72.676  23.581  1.00 67.24 ? 1   GLU   B OE1  1 
ATOM   4712  O  OE2  . GLU   B 1 2   ? 10.207  73.310  25.659  1.00 62.87 ? 1   GLU   B OE2  1 
ATOM   4713  N  N    . VAL   B 1 3   ? 15.572  73.054  25.286  1.00 27.92 ? 2   VAL   B N    1 
ATOM   4714  C  CA   . VAL   B 1 3   ? 16.347  72.096  26.064  1.00 28.54 ? 2   VAL   B CA   1 
ATOM   4715  C  C    . VAL   B 1 3   ? 15.452  71.685  27.225  1.00 34.44 ? 2   VAL   B C    1 
ATOM   4716  O  O    . VAL   B 1 3   ? 15.303  72.428  28.193  1.00 29.57 ? 2   VAL   B O    1 
ATOM   4717  C  CB   . VAL   B 1 3   ? 17.678  72.673  26.564  1.00 33.44 ? 2   VAL   B CB   1 
ATOM   4718  C  CG1  . VAL   B 1 3   ? 18.398  71.673  27.529  1.00 33.49 ? 2   VAL   B CG1  1 
ATOM   4719  C  CG2  . VAL   B 1 3   ? 18.575  73.086  25.406  1.00 31.96 ? 2   VAL   B CG2  1 
ATOM   4720  N  N    . ARG   B 1 4   ? 14.793  70.562  27.119  1.00 34.17 ? 3   ARG   B N    1 
ATOM   4721  C  CA   . ARG   B 1 4   ? 14.002  70.113  28.240  1.00 38.93 ? 3   ARG   B CA   1 
ATOM   4722  C  C    . ARG   B 1 4   ? 14.821  69.088  28.962  1.00 34.96 ? 3   ARG   B C    1 
ATOM   4723  O  O    . ARG   B 1 4   ? 15.730  68.501  28.420  1.00 36.74 ? 3   ARG   B O    1 
ATOM   4724  C  CB   . ARG   B 1 4   ? 12.704  69.509  27.791  1.00 47.80 ? 3   ARG   B CB   1 
ATOM   4725  C  CG   . ARG   B 1 4   ? 11.679  70.544  27.437  1.00 57.63 ? 3   ARG   B CG   1 
ATOM   4726  C  CD   . ARG   B 1 4   ? 10.591  69.930  26.628  1.00 61.67 ? 3   ARG   B CD   1 
ATOM   4727  N  NE   . ARG   B 1 4   ? 9.387   69.772  27.395  1.00 72.03 ? 3   ARG   B NE   1 
ATOM   4728  C  CZ   . ARG   B 1 4   ? 8.224   70.320  27.061  1.00 75.37 ? 3   ARG   B CZ   1 
ATOM   4729  N  NH1  . ARG   B 1 4   ? 8.134   71.067  25.971  1.00 66.99 ? 3   ARG   B NH1  1 
ATOM   4730  N  NH2  . ARG   B 1 4   ? 7.149   70.106  27.803  1.00 73.77 ? 3   ARG   B NH2  1 
ATOM   4731  H  H    . ARG   B 1 4   ? 14.781  70.048  26.429  1.00 41.00 ? 3   ARG   B H    1 
ATOM   4732  H  HA   . ARG   B 1 4   ? 13.817  70.862  28.844  1.00 46.72 ? 3   ARG   B HA   1 
ATOM   4733  H  HB2  . ARG   B 1 4   ? 12.864  68.963  27.005  1.00 57.36 ? 3   ARG   B HB2  1 
ATOM   4734  H  HB3  . ARG   B 1 4   ? 12.345  68.962  28.506  1.00 57.36 ? 3   ARG   B HB3  1 
ATOM   4735  H  HG2  . ARG   B 1 4   ? 11.292  70.907  28.249  1.00 69.16 ? 3   ARG   B HG2  1 
ATOM   4736  H  HG3  . ARG   B 1 4   ? 12.094  71.247  26.913  1.00 69.16 ? 3   ARG   B HG3  1 
ATOM   4737  H  HD2  . ARG   B 1 4   ? 10.395  70.502  25.870  1.00 74.00 ? 3   ARG   B HD2  1 
ATOM   4738  H  HD3  . ARG   B 1 4   ? 10.873  69.053  26.323  1.00 74.00 ? 3   ARG   B HD3  1 
ATOM   4739  H  HE   . ARG   B 1 4   ? 9.455   69.348  28.264  1.00 86.43 ? 3   ARG   B HE   1 
ATOM   4740  H  HH11 . ARG   B 1 4   ? 7.382   71.421  25.751  1.00 80.39 ? 3   ARG   B HH11 1 
ATOM   4741  H  HH12 . ARG   B 1 4   ? 8.828   71.193  25.483  1.00 80.39 ? 3   ARG   B HH12 1 
ATOM   4742  H  HH21 . ARG   B 1 4   ? 6.400   70.469  27.588  1.00 88.52 ? 3   ARG   B HH21 1 
ATOM   4743  H  HH22 . ARG   B 1 4   ? 7.205   69.626  28.515  1.00 88.52 ? 3   ARG   B HH22 1 
ATOM   4744  N  N    . THR   B 1 5   ? 14.502  68.668  30.186  1.00 39.58 ? 4   THR   B N    1 
ATOM   4745  C  CA   . THR   B 1 5   ? 15.196  67.701  31.018  1.00 38.55 ? 4   THR   B CA   1 
ATOM   4746  C  C    . THR   B 1 5   ? 14.198  66.865  31.806  1.00 43.57 ? 4   THR   B C    1 
ATOM   4747  O  O    . THR   B 1 5   ? 13.077  67.300  32.091  1.00 35.96 ? 4   THR   B O    1 
ATOM   4748  C  CB   . THR   B 1 5   ? 16.164  68.371  31.988  1.00 33.35 ? 4   THR   B CB   1 
ATOM   4749  O  OG1  . THR   B 1 5   ? 15.430  69.063  33.009  1.00 50.10 ? 4   THR   B OG1  1 
ATOM   4750  C  CG2  . THR   B 1 5   ? 17.061  69.362  31.290  1.00 46.36 ? 4   THR   B CG2  1 
ATOM   4751  H  H    . THR   B 1 5   ? 13.836  69.054  30.569  1.00 47.50 ? 4   THR   B H    1 
ATOM   4752  H  HA   . THR   B 1 5   ? 15.696  67.105  30.438  1.00 46.26 ? 4   THR   B HA   1 
ATOM   4753  H  HB   . THR   B 1 5   ? 16.721  67.683  32.382  1.00 40.02 ? 4   THR   B HB   1 
ATOM   4754  H  HG1  . THR   B 1 5   ? 15.344  69.873  32.802  1.00 60.12 ? 4   THR   B HG1  1 
ATOM   4755  H  HG21 . THR   B 1 5   ? 17.786  69.626  31.879  1.00 55.63 ? 4   THR   B HG21 1 
ATOM   4756  H  HG22 . THR   B 1 5   ? 17.436  68.964  30.489  1.00 55.63 ? 4   THR   B HG22 1 
ATOM   4757  H  HG23 . THR   B 1 5   ? 16.555  70.151  31.042  1.00 55.63 ? 4   THR   B HG23 1 
ATOM   4758  N  N    . ILE   B 1 6   ? 14.622  65.637  32.136  1.00 39.78 ? 5   ILE   B N    1 
ATOM   4759  C  CA   . ILE   B 1 6   ? 13.902  64.801  33.088  1.00 36.75 ? 5   ILE   B CA   1 
ATOM   4760  C  C    . ILE   B 1 6   ? 14.909  64.295  34.112  1.00 31.81 ? 5   ILE   B C    1 
ATOM   4761  O  O    . ILE   B 1 6   ? 16.122  64.330  33.890  1.00 32.24 ? 5   ILE   B O    1 
ATOM   4762  C  CB   . ILE   B 1 6   ? 13.161  63.615  32.420  1.00 36.19 ? 5   ILE   B CB   1 
ATOM   4763  C  CG1  . ILE   B 1 6   ? 14.109  62.767  31.580  1.00 31.18 ? 5   ILE   B CG1  1 
ATOM   4764  C  CG2  . ILE   B 1 6   ? 11.968  64.096  31.588  1.00 34.96 ? 5   ILE   B CG2  1 
ATOM   4765  C  CD1  . ILE   B 1 6   ? 13.582  61.347  31.250  1.00 35.16 ? 5   ILE   B CD1  1 
ATOM   4766  N  N    . LYS   B 1 7   ? 14.397  63.860  35.258  1.00 31.74 ? 6   LYS   B N    1 
ATOM   4767  C  CA   . LYS   B 1 7   ? 15.214  63.204  36.277  1.00 34.23 ? 6   LYS   B CA   1 
ATOM   4768  C  C    . LYS   B 1 7   ? 15.058  61.692  36.127  1.00 30.98 ? 6   LYS   B C    1 
ATOM   4769  O  O    . LYS   B 1 7   ? 13.937  61.202  35.985  1.00 28.69 ? 6   LYS   B O    1 
ATOM   4770  C  CB   . LYS   B 1 7   ? 14.797  63.640  37.687  1.00 38.01 ? 6   LYS   B CB   1 
ATOM   4771  C  CG   . LYS   B 1 7   ? 15.459  62.826  38.788  1.00 43.59 ? 6   LYS   B CG   1 
ATOM   4772  C  CD   . LYS   B 1 7   ? 14.473  61.971  39.589  1.00 52.03 ? 6   LYS   B CD   1 
ATOM   4773  C  CE   . LYS   B 1 7   ? 13.758  62.774  40.672  1.00 53.71 ? 6   LYS   B CE   1 
ATOM   4774  N  NZ   . LYS   B 1 7   ? 12.345  62.328  40.800  1.00 60.53 ? 6   LYS   B NZ   1 
ATOM   4775  N  N    . VAL   B 1 8   ? 16.172  60.969  36.126  1.00 27.29 ? 7   VAL   B N    1 
ATOM   4776  C  CA   . VAL   B 1 8   ? 16.176  59.507  36.176  1.00 25.72 ? 7   VAL   B CA   1 
ATOM   4777  C  C    . VAL   B 1 8   ? 17.211  59.082  37.211  1.00 26.98 ? 7   VAL   B C    1 
ATOM   4778  O  O    . VAL   B 1 8   ? 17.923  59.912  37.781  1.00 25.89 ? 7   VAL   B O    1 
ATOM   4779  C  CB   . VAL   B 1 8   ? 16.507  58.847  34.821  1.00 27.38 ? 7   VAL   B CB   1 
ATOM   4780  C  CG1  . VAL   B 1 8   ? 15.618  59.387  33.703  1.00 28.78 ? 7   VAL   B CG1  1 
ATOM   4781  C  CG2  . VAL   B 1 8   ? 17.996  59.007  34.504  1.00 29.25 ? 7   VAL   B CG2  1 
ATOM   4782  H  H    . VAL   B 1 8   ? 16.961  61.310  36.095  1.00 32.75 ? 7   VAL   B H    1 
ATOM   4783  H  HA   . VAL   B 1 8   ? 15.291  59.213  36.445  1.00 30.87 ? 7   VAL   B HA   1 
ATOM   4784  H  HB   . VAL   B 1 8   ? 16.320  57.897  34.881  1.00 32.85 ? 7   VAL   B HB   1 
ATOM   4785  H  HG11 . VAL   B 1 8   ? 15.654  58.778  32.949  1.00 34.54 ? 7   VAL   B HG11 1 
ATOM   4786  H  HG12 . VAL   B 1 8   ? 14.707  59.456  34.029  1.00 34.54 ? 7   VAL   B HG12 1 
ATOM   4787  H  HG13 . VAL   B 1 8   ? 15.942  60.262  33.437  1.00 34.54 ? 7   VAL   B HG13 1 
ATOM   4788  H  HG21 . VAL   B 1 8   ? 18.488  58.285  34.924  1.00 35.10 ? 7   VAL   B HG21 1 
ATOM   4789  H  HG22 . VAL   B 1 8   ? 18.119  58.975  33.542  1.00 35.10 ? 7   VAL   B HG22 1 
ATOM   4790  H  HG23 . VAL   B 1 8   ? 18.302  59.861  34.848  1.00 35.10 ? 7   VAL   B HG23 1 
ATOM   4791  N  N    . PHE   B 1 9   ? 17.302  57.770  37.434  1.00 26.65 ? 8   PHE   B N    1 
ATOM   4792  C  CA   . PHE   B 1 9   ? 18.341  57.194  38.281  1.00 25.31 ? 8   PHE   B CA   1 
ATOM   4793  C  C    . PHE   B 1 9   ? 19.242  56.314  37.438  1.00 21.34 ? 8   PHE   B C    1 
ATOM   4794  O  O    . PHE   B 1 9   ? 18.751  55.548  36.614  1.00 24.87 ? 8   PHE   B O    1 
ATOM   4795  C  CB   . PHE   B 1 9   ? 17.753  56.355  39.436  1.00 25.63 ? 8   PHE   B CB   1 
ATOM   4796  C  CG   . PHE   B 1 9   ? 16.854  57.132  40.331  1.00 22.30 ? 8   PHE   B CG   1 
ATOM   4797  C  CD1  . PHE   B 1 9   ? 17.385  57.934  41.318  1.00 26.70 ? 8   PHE   B CD1  1 
ATOM   4798  C  CD2  . PHE   B 1 9   ? 15.480  57.089  40.172  1.00 23.96 ? 8   PHE   B CD2  1 
ATOM   4799  C  CE1  . PHE   B 1 9   ? 16.564  58.667  42.134  1.00 29.68 ? 8   PHE   B CE1  1 
ATOM   4800  C  CE2  . PHE   B 1 9   ? 14.665  57.842  40.965  1.00 34.02 ? 8   PHE   B CE2  1 
ATOM   4801  C  CZ   . PHE   B 1 9   ? 15.212  58.625  41.959  1.00 31.69 ? 8   PHE   B CZ   1 
ATOM   4802  H  H    . PHE   B 1 9   ? 16.765  57.188  37.101  1.00 31.98 ? 8   PHE   B H    1 
ATOM   4803  H  HA   . PHE   B 1 9   ? 18.863  57.913  38.669  1.00 30.37 ? 8   PHE   B HA   1 
ATOM   4804  H  HB2  . PHE   B 1 9   ? 17.239  55.623  39.061  1.00 30.75 ? 8   PHE   B HB2  1 
ATOM   4805  H  HB3  . PHE   B 1 9   ? 18.481  56.008  39.973  1.00 30.75 ? 8   PHE   B HB3  1 
ATOM   4806  H  HD1  . PHE   B 1 9   ? 18.307  57.979  41.430  1.00 32.04 ? 8   PHE   B HD1  1 
ATOM   4807  H  HD2  . PHE   B 1 9   ? 15.109  56.541  39.518  1.00 28.75 ? 8   PHE   B HD2  1 
ATOM   4808  H  HE1  . PHE   B 1 9   ? 16.928  59.194  42.808  1.00 35.62 ? 8   PHE   B HE1  1 
ATOM   4809  H  HE2  . PHE   B 1 9   ? 13.744  57.828  40.835  1.00 40.83 ? 8   PHE   B HE2  1 
ATOM   4810  H  HZ   . PHE   B 1 9   ? 14.658  59.125  42.513  1.00 38.02 ? 8   PHE   B HZ   1 
ATOM   4811  N  N    . THR   B 1 10  ? 20.550  56.396  37.664  1.00 23.90 ? 9   THR   B N    1 
ATOM   4812  C  CA   . THR   B 1 10  ? 21.473  55.429  37.092  1.00 28.12 ? 9   THR   B CA   1 
ATOM   4813  C  C    . THR   B 1 10  ? 22.011  54.523  38.194  1.00 26.08 ? 9   THR   B C    1 
ATOM   4814  O  O    . THR   B 1 10  ? 22.024  54.866  39.384  1.00 24.75 ? 9   THR   B O    1 
ATOM   4815  C  CB   . THR   B 1 10  ? 22.653  56.081  36.367  1.00 26.35 ? 9   THR   B CB   1 
ATOM   4816  O  OG1  . THR   B 1 10  ? 23.318  56.998  37.231  1.00 25.99 ? 9   THR   B OG1  1 
ATOM   4817  C  CG2  . THR   B 1 10  ? 22.158  56.813  35.115  1.00 33.92 ? 9   THR   B CG2  1 
ATOM   4818  H  H    . THR   B 1 10  ? 20.923  57.004  38.145  1.00 28.67 ? 9   THR   B H    1 
ATOM   4819  H  HA   . THR   B 1 10  ? 20.987  54.905  36.436  1.00 33.74 ? 9   THR   B HA   1 
ATOM   4820  H  HB   . THR   B 1 10  ? 23.286  55.397  36.099  1.00 31.62 ? 9   THR   B HB   1 
ATOM   4821  H  HG1  . THR   B 1 10  ? 23.868  56.588  37.716  1.00 31.18 ? 9   THR   B HG1  1 
ATOM   4822  H  HG21 . THR   B 1 10  ? 22.882  57.327  34.724  1.00 40.70 ? 9   THR   B HG21 1 
ATOM   4823  H  HG22 . THR   B 1 10  ? 21.838  56.172  34.461  1.00 40.70 ? 9   THR   B HG22 1 
ATOM   4824  H  HG23 . THR   B 1 10  ? 21.434  57.414  35.346  1.00 40.70 ? 9   THR   B HG23 1 
ATOM   4825  N  N    . THR   B 1 11  ? 22.454  53.346  37.780  1.00 26.45 ? 10  THR   B N    1 
ATOM   4826  C  CA   . THR   B 1 11  ? 22.893  52.341  38.737  1.00 24.05 ? 10  THR   B CA   1 
ATOM   4827  C  C    . THR   B 1 11  ? 23.742  51.318  37.994  1.00 25.46 ? 10  THR   B C    1 
ATOM   4828  O  O    . THR   B 1 11  ? 23.629  51.157  36.776  1.00 26.15 ? 10  THR   B O    1 
ATOM   4829  C  CB   . THR   B 1 11  ? 21.699  51.663  39.418  1.00 23.20 ? 10  THR   B CB   1 
ATOM   4830  O  OG1  . THR   B 1 11  ? 22.156  50.890  40.535  1.00 25.55 ? 10  THR   B OG1  1 
ATOM   4831  C  CG2  . THR   B 1 11  ? 20.951  50.735  38.437  1.00 22.88 ? 10  THR   B CG2  1 
ATOM   4832  H  H    . THR   B 1 11  ? 22.510  53.106  36.957  1.00 31.74 ? 10  THR   B H    1 
ATOM   4833  H  HA   . THR   B 1 11  ? 23.438  52.755  39.424  1.00 28.86 ? 10  THR   B HA   1 
ATOM   4834  H  HB   . THR   B 1 11  ? 21.081  52.347  39.720  1.00 27.84 ? 10  THR   B HB   1 
ATOM   4835  H  HG1  . THR   B 1 11  ? 21.680  51.050  41.209  1.00 30.66 ? 10  THR   B HG1  1 
ATOM   4836  H  HG21 . THR   B 1 11  ? 20.062  50.543  38.774  1.00 27.46 ? 10  THR   B HG21 1 
ATOM   4837  H  HG22 . THR   B 1 11  ? 20.873  51.162  37.570  1.00 27.46 ? 10  THR   B HG22 1 
ATOM   4838  H  HG23 . THR   B 1 11  ? 21.436  49.901  38.334  1.00 27.46 ? 10  THR   B HG23 1 
ATOM   4839  N  N    . VAL   B 1 12  ? 24.596  50.634  38.750  1.00 28.30 ? 11  VAL   B N    1 
ATOM   4840  C  CA   . VAL   B 1 12  ? 25.215  49.409  38.264  1.00 28.89 ? 11  VAL   B CA   1 
ATOM   4841  C  C    . VAL   B 1 12  ? 24.702  48.171  38.986  1.00 27.74 ? 11  VAL   B C    1 
ATOM   4842  O  O    . VAL   B 1 12  ? 24.940  47.060  38.496  1.00 27.65 ? 11  VAL   B O    1 
ATOM   4843  C  CB   . VAL   B 1 12  ? 26.757  49.469  38.348  1.00 27.56 ? 11  VAL   B CB   1 
ATOM   4844  C  CG1  . VAL   B 1 12  ? 27.297  50.615  37.478  1.00 33.37 ? 11  VAL   B CG1  1 
ATOM   4845  C  CG2  . VAL   B 1 12  ? 27.225  49.592  39.794  1.00 30.29 ? 11  VAL   B CG2  1 
ATOM   4846  H  H    . VAL   B 1 12  ? 24.831  50.859  39.546  1.00 33.96 ? 11  VAL   B H    1 
ATOM   4847  H  HA   . VAL   B 1 12  ? 24.988  49.313  37.326  1.00 34.67 ? 11  VAL   B HA   1 
ATOM   4848  H  HB   . VAL   B 1 12  ? 27.122  48.640  38.003  1.00 33.07 ? 11  VAL   B HB   1 
ATOM   4849  H  HG11 . VAL   B 1 12  ? 27.955  50.259  36.860  1.00 40.04 ? 11  VAL   B HG11 1 
ATOM   4850  H  HG12 . VAL   B 1 12  ? 26.561  51.011  36.985  1.00 40.04 ? 11  VAL   B HG12 1 
ATOM   4851  H  HG13 . VAL   B 1 12  ? 27.707  51.280  38.051  1.00 40.04 ? 11  VAL   B HG13 1 
ATOM   4852  H  HG21 . VAL   B 1 12  ? 28.057  50.089  39.815  1.00 36.35 ? 11  VAL   B HG21 1 
ATOM   4853  H  HG22 . VAL   B 1 12  ? 26.547  50.059  40.307  1.00 36.35 ? 11  VAL   B HG22 1 
ATOM   4854  H  HG23 . VAL   B 1 12  ? 27.361  48.703  40.158  1.00 36.35 ? 11  VAL   B HG23 1 
ATOM   4855  N  N    . ASP   B 1 13  ? 24.041  48.314  40.144  1.00 27.50 ? 12  ASP   B N    1 
ATOM   4856  C  CA   . ASP   B 1 13  ? 23.627  47.169  40.961  1.00 28.31 ? 12  ASP   B CA   1 
ATOM   4857  C  C    . ASP   B 1 13  ? 22.144  47.152  41.315  1.00 30.44 ? 12  ASP   B C    1 
ATOM   4858  O  O    . ASP   B 1 13  ? 21.671  46.188  41.948  1.00 29.28 ? 12  ASP   B O    1 
ATOM   4859  C  CB   . ASP   B 1 13  ? 24.438  47.132  42.263  1.00 26.87 ? 12  ASP   B CB   1 
ATOM   4860  C  CG   . ASP   B 1 13  ? 24.337  48.427  43.076  1.00 30.94 ? 12  ASP   B CG   1 
ATOM   4861  O  OD1  . ASP   B 1 13  ? 23.388  49.223  42.847  1.00 25.93 ? 12  ASP   B OD1  1 
ATOM   4862  O  OD2  . ASP   B 1 13  ? 25.188  48.612  43.983  1.00 30.40 ? 12  ASP   B OD2  1 
ATOM   4863  H  H    . ASP   B 1 13  ? 23.819  49.074  40.480  1.00 33.00 ? 12  ASP   B H    1 
ATOM   4864  H  HA   . ASP   B 1 13  ? 23.814  46.357  40.463  1.00 33.97 ? 12  ASP   B HA   1 
ATOM   4865  H  HB2  . ASP   B 1 13  ? 24.109  46.406  42.817  1.00 32.25 ? 12  ASP   B HB2  1 
ATOM   4866  H  HB3  . ASP   B 1 13  ? 25.372  46.988  42.048  1.00 32.25 ? 12  ASP   B HB3  1 
ATOM   4867  N  N    . ASN   B 1 14  ? 21.406  48.197  40.960  1.00 26.05 ? 13  ASN   B N    1 
ATOM   4868  C  CA   . ASN   B 1 14  ? 20.016  48.399  41.337  1.00 24.86 ? 13  ASN   B CA   1 
ATOM   4869  C  C    . ASN   B 1 14  ? 19.819  48.427  42.846  1.00 25.80 ? 13  ASN   B C    1 
ATOM   4870  O  O    . ASN   B 1 14  ? 18.706  48.271  43.320  1.00 27.32 ? 13  ASN   B O    1 
ATOM   4871  C  CB   . ASN   B 1 14  ? 19.091  47.358  40.700  1.00 32.56 ? 13  ASN   B CB   1 
ATOM   4872  C  CG   . ASN   B 1 14  ? 17.658  47.839  40.646  1.00 39.49 ? 13  ASN   B CG   1 
ATOM   4873  O  OD1  . ASN   B 1 14  ? 17.411  49.009  40.378  1.00 38.21 ? 13  ASN   B OD1  1 
ATOM   4874  N  ND2  . ASN   B 1 14  ? 16.709  46.948  40.888  1.00 39.20 ? 13  ASN   B ND2  1 
ATOM   4875  H  H    . ASN   B 1 14  ? 21.707  48.838  40.473  1.00 31.26 ? 13  ASN   B H    1 
ATOM   4876  H  HA   . ASN   B 1 14  ? 19.750  49.268  40.996  1.00 29.84 ? 13  ASN   B HA   1 
ATOM   4877  H  HB2  . ASN   B 1 14  ? 19.386  47.180  39.793  1.00 39.07 ? 13  ASN   B HB2  1 
ATOM   4878  H  HB3  . ASN   B 1 14  ? 19.118  46.543  41.224  1.00 39.07 ? 13  ASN   B HB3  1 
ATOM   4879  H  HD21 . ASN   B 1 14  ? 16.919  46.134  41.067  1.00 47.04 ? 13  ASN   B HD21 1 
ATOM   4880  H  HD22 . ASN   B 1 14  ? 15.882  47.184  40.866  1.00 47.04 ? 13  ASN   B HD22 1 
ATOM   4881  N  N    . ILE   B 1 15  ? 20.879  48.679  43.588  1.00 25.73 ? 14  ILE   B N    1 
ATOM   4882  C  CA   . ILE   B 1 15  ? 20.820  48.893  45.028  1.00 28.37 ? 14  ILE   B CA   1 
ATOM   4883  C  C    . ILE   B 1 15  ? 21.151  50.338  45.382  1.00 28.88 ? 14  ILE   B C    1 
ATOM   4884  O  O    . ILE   B 1 15  ? 20.472  50.955  46.207  1.00 27.15 ? 14  ILE   B O    1 
ATOM   4885  C  CB   . ILE   B 1 15  ? 21.768  47.924  45.768  1.00 28.20 ? 14  ILE   B CB   1 
ATOM   4886  C  CG1  . ILE   B 1 15  ? 21.321  46.472  45.576  1.00 32.91 ? 14  ILE   B CG1  1 
ATOM   4887  C  CG2  . ILE   B 1 15  ? 21.867  48.329  47.230  1.00 34.62 ? 14  ILE   B CG2  1 
ATOM   4888  C  CD1  . ILE   B 1 15  ? 19.926  46.213  45.996  1.00 35.39 ? 14  ILE   B CD1  1 
ATOM   4889  H  H    . ILE   B 1 15  ? 21.677  48.735  43.271  1.00 30.88 ? 14  ILE   B H    1 
ATOM   4890  H  HA   . ILE   B 1 15  ? 19.915  48.712  45.326  1.00 34.05 ? 14  ILE   B HA   1 
ATOM   4891  H  HB   . ILE   B 1 15  ? 22.659  47.983  45.387  1.00 33.84 ? 14  ILE   B HB   1 
ATOM   4892  H  HG12 . ILE   B 1 15  ? 21.393  46.247  44.635  1.00 39.49 ? 14  ILE   B HG12 1 
ATOM   4893  H  HG13 . ILE   B 1 15  ? 21.899  45.897  46.100  1.00 39.49 ? 14  ILE   B HG13 1 
ATOM   4894  H  HG21 . ILE   B 1 15  ? 22.096  47.549  47.759  1.00 41.54 ? 14  ILE   B HG21 1 
ATOM   4895  H  HG22 . ILE   B 1 15  ? 22.554  49.007  47.325  1.00 41.54 ? 14  ILE   B HG22 1 
ATOM   4896  H  HG23 . ILE   B 1 15  ? 21.011  48.684  47.518  1.00 41.54 ? 14  ILE   B HG23 1 
ATOM   4897  H  HD11 . ILE   B 1 15  ? 19.807  45.259  46.124  1.00 42.47 ? 14  ILE   B HD11 1 
ATOM   4898  H  HD12 . ILE   B 1 15  ? 19.754  46.683  46.827  1.00 42.47 ? 14  ILE   B HD12 1 
ATOM   4899  H  HD13 . ILE   B 1 15  ? 19.324  46.531  45.305  1.00 42.47 ? 14  ILE   B HD13 1 
ATOM   4900  N  N    . ASN   B 1 16  ? 22.246  50.857  44.816  1.00 26.52 ? 15  ASN   B N    1 
ATOM   4901  C  CA   . ASN   B 1 16  ? 22.672  52.245  44.963  1.00 27.03 ? 15  ASN   B CA   1 
ATOM   4902  C  C    . ASN   B 1 16  ? 22.219  52.986  43.712  1.00 27.00 ? 15  ASN   B C    1 
ATOM   4903  O  O    . ASN   B 1 16  ? 22.644  52.664  42.597  1.00 25.11 ? 15  ASN   B O    1 
ATOM   4904  C  CB   . ASN   B 1 16  ? 24.177  52.299  45.165  1.00 29.21 ? 15  ASN   B CB   1 
ATOM   4905  C  CG   . ASN   B 1 16  ? 24.595  51.578  46.435  1.00 32.32 ? 15  ASN   B CG   1 
ATOM   4906  O  OD1  . ASN   B 1 16  ? 24.472  52.119  47.507  1.00 33.19 ? 15  ASN   B OD1  1 
ATOM   4907  N  ND2  . ASN   B 1 16  ? 25.009  50.321  46.314  1.00 30.14 ? 15  ASN   B ND2  1 
ATOM   4908  H  H    . ASN   B 1 16  ? 22.780  50.400  44.321  1.00 31.82 ? 15  ASN   B H    1 
ATOM   4909  H  HA   . ASN   B 1 16  ? 22.257  52.669  45.731  1.00 32.44 ? 15  ASN   B HA   1 
ATOM   4910  H  HB2  . ASN   B 1 16  ? 24.616  51.873  44.413  1.00 35.05 ? 15  ASN   B HB2  1 
ATOM   4911  H  HB3  . ASN   B 1 16  ? 24.458  53.225  45.232  1.00 35.05 ? 15  ASN   B HB3  1 
ATOM   4912  H  HD21 . ASN   B 1 16  ? 25.254  49.880  47.011  1.00 36.17 ? 15  ASN   B HD21 1 
ATOM   4913  H  HD22 . ASN   B 1 16  ? 25.031  49.948  45.539  1.00 36.17 ? 15  ASN   B HD22 1 
ATOM   4914  N  N    . LEU   B 1 17  ? 21.304  53.928  43.897  1.00 24.21 ? 16  LEU   B N    1 
ATOM   4915  C  CA   . LEU   B 1 17  ? 20.693  54.681  42.809  1.00 22.23 ? 16  LEU   B CA   1 
ATOM   4916  C  C    . LEU   B 1 17  ? 21.262  56.096  42.815  1.00 22.77 ? 16  LEU   B C    1 
ATOM   4917  O  O    . LEU   B 1 17  ? 21.405  56.709  43.875  1.00 25.04 ? 16  LEU   B O    1 
ATOM   4918  C  CB   . LEU   B 1 17  ? 19.179  54.696  42.988  1.00 23.39 ? 16  LEU   B CB   1 
ATOM   4919  C  CG   . LEU   B 1 17  ? 18.498  53.336  43.031  1.00 26.50 ? 16  LEU   B CG   1 
ATOM   4920  C  CD1  . LEU   B 1 17  ? 16.991  53.561  43.023  1.00 28.06 ? 16  LEU   B CD1  1 
ATOM   4921  C  CD2  . LEU   B 1 17  ? 18.934  52.462  41.862  1.00 24.59 ? 16  LEU   B CD2  1 
ATOM   4922  H  H    . LEU   B 1 17  ? 21.010  54.158  44.672  1.00 29.05 ? 16  LEU   B H    1 
ATOM   4923  H  HA   . LEU   B 1 17  ? 20.889  54.286  41.945  1.00 26.67 ? 16  LEU   B HA   1 
ATOM   4924  H  HB2  . LEU   B 1 17  ? 18.977  55.145  43.824  1.00 28.06 ? 16  LEU   B HB2  1 
ATOM   4925  H  HB3  . LEU   B 1 17  ? 18.792  55.188  42.246  1.00 28.06 ? 16  LEU   B HB3  1 
ATOM   4926  H  HG   . LEU   B 1 17  ? 18.749  52.857  43.836  1.00 31.80 ? 16  LEU   B HG   1 
ATOM   4927  H  HD11 . LEU   B 1 17  ? 16.544  52.712  43.161  1.00 33.67 ? 16  LEU   B HD11 1 
ATOM   4928  H  HD12 . LEU   B 1 17  ? 16.759  54.177  43.736  1.00 33.67 ? 16  LEU   B HD12 1 
ATOM   4929  H  HD13 . LEU   B 1 17  ? 16.732  53.935  42.166  1.00 33.67 ? 16  LEU   B HD13 1 
ATOM   4930  H  HD21 . LEU   B 1 17  ? 18.258  51.785  41.704  1.00 29.51 ? 16  LEU   B HD21 1 
ATOM   4931  H  HD22 . LEU   B 1 17  ? 19.036  53.018  41.073  1.00 29.51 ? 16  LEU   B HD22 1 
ATOM   4932  H  HD23 . LEU   B 1 17  ? 19.780  52.041  42.081  1.00 29.51 ? 16  LEU   B HD23 1 
ATOM   4933  N  N    . HIS   B 1 18  ? 21.600  56.612  41.631  1.00 23.61 ? 17  HIS   B N    1 
ATOM   4934  C  CA   . HIS   B 1 18  ? 22.288  57.893  41.503  1.00 25.98 ? 17  HIS   B CA   1 
ATOM   4935  C  C    . HIS   B 1 18  ? 21.443  58.825  40.650  1.00 25.59 ? 17  HIS   B C    1 
ATOM   4936  O  O    . HIS   B 1 18  ? 21.243  58.572  39.462  1.00 27.13 ? 17  HIS   B O    1 
ATOM   4937  C  CB   . HIS   B 1 18  ? 23.695  57.718  40.926  1.00 26.05 ? 17  HIS   B CB   1 
ATOM   4938  C  CG   . HIS   B 1 18  ? 24.493  56.665  41.631  1.00 27.90 ? 17  HIS   B CG   1 
ATOM   4939  N  ND1  . HIS   B 1 18  ? 24.921  56.811  42.935  1.00 29.03 ? 17  HIS   B ND1  1 
ATOM   4940  C  CD2  . HIS   B 1 18  ? 24.936  55.450  41.222  1.00 29.53 ? 17  HIS   B CD2  1 
ATOM   4941  C  CE1  . HIS   B 1 18  ? 25.578  55.723  43.302  1.00 34.78 ? 17  HIS   B CE1  1 
ATOM   4942  N  NE2  . HIS   B 1 18  ? 25.611  54.886  42.278  1.00 32.73 ? 17  HIS   B NE2  1 
ATOM   4943  H  H    . HIS   B 1 18  ? 21.437  56.231  40.878  1.00 28.33 ? 17  HIS   B H    1 
ATOM   4944  H  HA   . HIS   B 1 18  ? 22.374  58.293  42.382  1.00 31.17 ? 17  HIS   B HA   1 
ATOM   4945  H  HB2  . HIS   B 1 18  ? 23.623  57.464  39.993  1.00 31.26 ? 17  HIS   B HB2  1 
ATOM   4946  H  HB3  . HIS   B 1 18  ? 24.174  58.558  41.005  1.00 31.26 ? 17  HIS   B HB3  1 
ATOM   4947  H  HD2  . HIS   B 1 18  ? 24.808  55.069  40.383  1.00 35.44 ? 17  HIS   B HD2  1 
ATOM   4948  H  HE1  . HIS   B 1 18  ? 25.954  55.573  44.139  1.00 41.74 ? 17  HIS   B HE1  1 
ATOM   4949  H  HE2  . HIS   B 1 18  ? 25.992  54.115  42.275  1.00 39.28 ? 17  HIS   B HE2  1 
ATOM   4950  N  N    . THR   B 1 19  ? 20.934  59.892  41.266  1.00 24.83 ? 18  THR   B N    1 
ATOM   4951  C  CA   . THR   B 1 19  ? 20.032  60.791  40.558  1.00 24.81 ? 18  THR   B CA   1 
ATOM   4952  C  C    . THR   B 1 19  ? 20.785  61.514  39.458  1.00 23.65 ? 18  THR   B C    1 
ATOM   4953  O  O    . THR   B 1 19  ? 21.872  62.055  39.684  1.00 30.52 ? 18  THR   B O    1 
ATOM   4954  C  CB   . THR   B 1 19  ? 19.413  61.819  41.506  1.00 26.49 ? 18  THR   B CB   1 
ATOM   4955  O  OG1  . THR   B 1 19  ? 18.882  61.153  42.640  1.00 30.82 ? 18  THR   B OG1  1 
ATOM   4956  C  CG2  . THR   B 1 19  ? 18.309  62.622  40.795  1.00 33.31 ? 18  THR   B CG2  1 
ATOM   4957  H  H    . THR   B 1 19  ? 21.095  60.113  42.081  1.00 29.79 ? 18  THR   B H    1 
ATOM   4958  H  HA   . THR   B 1 19  ? 19.313  60.266  40.173  1.00 29.77 ? 18  THR   B HA   1 
ATOM   4959  H  HB   . THR   B 1 19  ? 20.091  62.449  41.796  1.00 31.79 ? 18  THR   B HB   1 
ATOM   4960  H  HG1  . THR   B 1 19  ? 18.576  60.403  42.416  1.00 36.98 ? 18  THR   B HG1  1 
ATOM   4961  H  HG21 . THR   B 1 19  ? 17.644  62.913  41.439  1.00 39.98 ? 18  THR   B HG21 1 
ATOM   4962  H  HG22 . THR   B 1 19  ? 18.692  63.401  40.363  1.00 39.98 ? 18  THR   B HG22 1 
ATOM   4963  H  HG23 . THR   B 1 19  ? 17.877  62.070  40.124  1.00 39.98 ? 18  THR   B HG23 1 
ATOM   4964  N  N    . GLN   B 1 20  ? 20.207  61.521  38.278  1.00 29.99 ? 19  GLN   B N    1 
ATOM   4965  C  CA   . GLN   B 1 20  ? 20.735  62.286  37.155  1.00 31.96 ? 19  GLN   B CA   1 
ATOM   4966  C  C    . GLN   B 1 20  ? 19.648  63.191  36.594  1.00 34.17 ? 19  GLN   B C    1 
ATOM   4967  O  O    . GLN   B 1 20  ? 18.470  62.827  36.575  1.00 34.22 ? 19  GLN   B O    1 
ATOM   4968  C  CB   . GLN   B 1 20  ? 21.227  61.402  36.006  1.00 30.87 ? 19  GLN   B CB   1 
ATOM   4969  C  CG   . GLN   B 1 20  ? 22.215  60.295  36.314  1.00 35.09 ? 19  GLN   B CG   1 
ATOM   4970  C  CD   . GLN   B 1 20  ? 23.464  60.768  37.010  1.00 36.10 ? 19  GLN   B CD   1 
ATOM   4971  O  OE1  . GLN   B 1 20  ? 23.888  61.908  36.847  1.00 37.29 ? 19  GLN   B OE1  1 
ATOM   4972  N  NE2  . GLN   B 1 20  ? 24.089  59.876  37.767  1.00 35.39 ? 19  GLN   B NE2  1 
ATOM   4973  H  H    . GLN   B 1 20  ? 19.492  61.082  38.091  1.00 35.98 ? 19  GLN   B H    1 
ATOM   4974  H  HA   . GLN   B 1 20  ? 21.478  62.814  37.487  1.00 38.35 ? 19  GLN   B HA   1 
ATOM   4975  H  HB2  . GLN   B 1 20  ? 20.450  60.976  35.611  1.00 37.05 ? 19  GLN   B HB2  1 
ATOM   4976  H  HB3  . GLN   B 1 20  ? 21.655  61.980  35.355  1.00 37.05 ? 19  GLN   B HB3  1 
ATOM   4977  H  HG2  . GLN   B 1 20  ? 21.784  59.645  36.891  1.00 42.11 ? 19  GLN   B HG2  1 
ATOM   4978  H  HG3  . GLN   B 1 20  ? 22.482  59.875  35.482  1.00 42.11 ? 19  GLN   B HG3  1 
ATOM   4979  H  HE21 . GLN   B 1 20  ? 23.776  59.078  37.838  1.00 42.47 ? 19  GLN   B HE21 1 
ATOM   4980  H  HE22 . GLN   B 1 20  ? 24.807  60.095  38.186  1.00 42.47 ? 19  GLN   B HE22 1 
ATOM   4981  N  N    . VAL   B 1 21  ? 20.066  64.364  36.110  1.00 39.24 ? 20  VAL   B N    1 
ATOM   4982  C  CA   . VAL   B 1 21  ? 19.234  65.230  35.277  1.00 40.18 ? 20  VAL   B CA   1 
ATOM   4983  C  C    . VAL   B 1 21  ? 19.702  65.012  33.847  1.00 34.03 ? 20  VAL   B C    1 
ATOM   4984  O  O    . VAL   B 1 21  ? 20.889  65.189  33.551  1.00 42.16 ? 20  VAL   B O    1 
ATOM   4985  C  CB   . VAL   B 1 21  ? 19.368  66.709  35.673  1.00 37.94 ? 20  VAL   B CB   1 
ATOM   4986  C  CG1  . VAL   B 1 21  ? 18.722  67.600  34.579  1.00 40.40 ? 20  VAL   B CG1  1 
ATOM   4987  C  CG2  . VAL   B 1 21  ? 18.764  66.963  37.049  1.00 43.52 ? 20  VAL   B CG2  1 
ATOM   4988  H  H    . VAL   B 1 21  ? 20.850  64.686  36.255  1.00 47.09 ? 20  VAL   B H    1 
ATOM   4989  H  HA   . VAL   B 1 21  ? 18.299  64.985  35.367  1.00 48.22 ? 20  VAL   B HA   1 
ATOM   4990  H  HB   . VAL   B 1 21  ? 20.306  66.947  35.738  1.00 45.53 ? 20  VAL   B HB   1 
ATOM   4991  H  HG11 . VAL   B 1 21  ? 17.954  67.138  34.208  1.00 48.48 ? 20  VAL   B HG11 1 
ATOM   4992  H  HG12 . VAL   B 1 21  ? 18.443  68.439  34.978  1.00 48.48 ? 20  VAL   B HG12 1 
ATOM   4993  H  HG13 . VAL   B 1 21  ? 19.376  67.767  33.881  1.00 48.48 ? 20  VAL   B HG13 1 
ATOM   4994  H  HG21 . VAL   B 1 21  ? 17.805  66.824  37.003  1.00 52.22 ? 20  VAL   B HG21 1 
ATOM   4995  H  HG22 . VAL   B 1 21  ? 19.157  66.345  37.685  1.00 52.22 ? 20  VAL   B HG22 1 
ATOM   4996  H  HG23 . VAL   B 1 21  ? 18.953  67.876  37.314  1.00 52.22 ? 20  VAL   B HG23 1 
ATOM   4997  N  N    . VAL   B 1 22  ? 18.808  64.582  32.964  1.00 31.94 ? 21  VAL   B N    1 
ATOM   4998  C  CA   . VAL   B 1 22  ? 19.187  64.203  31.606  1.00 35.86 ? 21  VAL   B CA   1 
ATOM   4999  C  C    . VAL   B 1 22  ? 18.583  65.174  30.596  1.00 38.82 ? 21  VAL   B C    1 
ATOM   5000  O  O    . VAL   B 1 22  ? 17.418  65.563  30.712  1.00 33.24 ? 21  VAL   B O    1 
ATOM   5001  C  CB   . VAL   B 1 22  ? 18.758  62.757  31.285  1.00 40.92 ? 21  VAL   B CB   1 
ATOM   5002  C  CG1  . VAL   B 1 22  ? 17.247  62.623  31.313  1.00 40.46 ? 21  VAL   B CG1  1 
ATOM   5003  C  CG2  . VAL   B 1 22  ? 19.280  62.338  29.937  1.00 44.84 ? 21  VAL   B CG2  1 
ATOM   5004  H  H    . VAL   B 1 22  ? 17.968  64.501  33.129  1.00 38.32 ? 21  VAL   B H    1 
ATOM   5005  H  HA   . VAL   B 1 22  ? 20.152  64.271  31.535  1.00 43.03 ? 21  VAL   B HA   1 
ATOM   5006  H  HB   . VAL   B 1 22  ? 19.131  62.172  31.963  1.00 49.10 ? 21  VAL   B HB   1 
ATOM   5007  H  HG11 . VAL   B 1 22  ? 17.016  61.705  31.526  1.00 48.55 ? 21  VAL   B HG11 1 
ATOM   5008  H  HG12 . VAL   B 1 22  ? 16.889  63.220  31.988  1.00 48.55 ? 21  VAL   B HG12 1 
ATOM   5009  H  HG13 . VAL   B 1 22  ? 16.893  62.858  30.441  1.00 48.55 ? 21  VAL   B HG13 1 
ATOM   5010  H  HG21 . VAL   B 1 22  ? 18.972  61.439  29.744  1.00 53.81 ? 21  VAL   B HG21 1 
ATOM   5011  H  HG22 . VAL   B 1 22  ? 18.948  62.953  29.264  1.00 53.81 ? 21  VAL   B HG22 1 
ATOM   5012  H  HG23 . VAL   B 1 22  ? 20.250  62.359  29.953  1.00 53.81 ? 21  VAL   B HG23 1 
ATOM   5013  N  N    . ASP   B 1 23  ? 19.378  65.519  29.584  1.00 41.65 ? 22  ASP   B N    1 
ATOM   5014  C  CA   . ASP   B 1 23  ? 18.988  66.383  28.461  1.00 36.12 ? 22  ASP   B CA   1 
ATOM   5015  C  C    . ASP   B 1 23  ? 18.237  65.573  27.412  1.00 28.72 ? 22  ASP   B C    1 
ATOM   5016  O  O    . ASP   B 1 23  ? 18.791  64.659  26.792  1.00 38.70 ? 22  ASP   B O    1 
ATOM   5017  C  CB   . ASP   B 1 23  ? 20.259  67.028  27.907  1.00 42.66 ? 22  ASP   B CB   1 
ATOM   5018  C  CG   . ASP   B 1 23  ? 20.004  68.083  26.831  1.00 38.77 ? 22  ASP   B CG   1 
ATOM   5019  O  OD1  . ASP   B 1 23  ? 18.937  68.080  26.195  1.00 35.62 ? 22  ASP   B OD1  1 
ATOM   5020  O  OD2  . ASP   B 1 23  ? 20.894  68.946  26.679  1.00 40.04 ? 22  ASP   B OD2  1 
ATOM   5021  H  H    . ASP   B 1 23  ? 20.193  65.252  29.517  1.00 49.98 ? 22  ASP   B H    1 
ATOM   5022  H  HA   . ASP   B 1 23  ? 18.373  67.075  28.751  1.00 43.34 ? 22  ASP   B HA   1 
ATOM   5023  H  HB2  . ASP   B 1 23  ? 20.732  67.460  28.636  1.00 51.19 ? 22  ASP   B HB2  1 
ATOM   5024  H  HB3  . ASP   B 1 23  ? 20.814  66.336  27.516  1.00 51.19 ? 22  ASP   B HB3  1 
ATOM   5025  N  N    . MET   B 1 24  ? 16.952  65.890  27.233  1.00 30.82 ? 23  MET   B N    1 
ATOM   5026  C  CA   . MET   B 1 24  ? 16.119  65.146  26.307  1.00 34.94 ? 23  MET   B CA   1 
ATOM   5027  C  C    . MET   B 1 24  ? 16.499  65.431  24.868  1.00 41.85 ? 23  MET   B C    1 
ATOM   5028  O  O    . MET   B 1 24  ? 16.088  64.681  23.974  1.00 37.30 ? 23  MET   B O    1 
ATOM   5029  C  CB   . MET   B 1 24  ? 14.657  65.482  26.547  1.00 36.20 ? 23  MET   B CB   1 
ATOM   5030  C  CG   . MET   B 1 24  ? 14.320  65.636  28.011  1.00 38.19 ? 23  MET   B CG   1 
ATOM   5031  S  SD   . MET   B 1 24  ? 12.560  65.628  28.343  1.00 42.60 ? 23  MET   B SD   1 
ATOM   5032  C  CE   . MET   B 1 24  ? 11.947  64.371  27.216  1.00 45.92 ? 23  MET   B CE   1 
ATOM   5033  H  H    . MET   B 1 24  ? 16.545  66.530  27.638  1.00 36.98 ? 23  MET   B H    1 
ATOM   5034  H  HA   . MET   B 1 24  ? 16.220  64.195  26.471  1.00 41.93 ? 23  MET   B HA   1 
ATOM   5035  H  HB2  . MET   B 1 24  ? 14.449  66.319  26.102  1.00 43.44 ? 23  MET   B HB2  1 
ATOM   5036  H  HB3  . MET   B 1 24  ? 14.107  64.769  26.186  1.00 43.44 ? 23  MET   B HB3  1 
ATOM   5037  H  HG2  . MET   B 1 24  ? 14.718  64.901  28.503  1.00 45.83 ? 23  MET   B HG2  1 
ATOM   5038  H  HG3  . MET   B 1 24  ? 14.678  66.480  28.328  1.00 45.83 ? 23  MET   B HG3  1 
ATOM   5039  H  HE1  . MET   B 1 24  ? 11.185  64.725  26.732  1.00 55.11 ? 23  MET   B HE1  1 
ATOM   5040  H  HE2  . MET   B 1 24  ? 12.652  64.132  26.594  1.00 55.11 ? 23  MET   B HE2  1 
ATOM   5041  H  HE3  . MET   B 1 24  ? 11.680  63.591  27.728  1.00 55.11 ? 23  MET   B HE3  1 
ATOM   5042  N  N    . SER   B 1 25  ? 17.326  66.456  24.644  1.00 40.98 ? 24  SER   B N    1 
ATOM   5043  C  CA   . SER   B 1 25  ? 17.832  66.758  23.316  1.00 46.68 ? 24  SER   B CA   1 
ATOM   5044  C  C    . SER   B 1 25  ? 19.065  65.943  22.952  1.00 49.35 ? 24  SER   B C    1 
ATOM   5045  O  O    . SER   B 1 25  ? 19.558  66.108  21.835  1.00 46.80 ? 24  SER   B O    1 
ATOM   5046  C  CB   . SER   B 1 25  ? 18.139  68.261  23.195  1.00 45.06 ? 24  SER   B CB   1 
ATOM   5047  O  OG   . SER   B 1 25  ? 19.420  68.610  23.711  1.00 49.57 ? 24  SER   B OG   1 
ATOM   5048  H  H    . SER   B 1 25  ? 17.607  66.992  25.255  1.00 49.17 ? 24  SER   B H    1 
ATOM   5049  H  HA   . SER   B 1 25  ? 17.142  66.547  22.667  1.00 56.02 ? 24  SER   B HA   1 
ATOM   5050  H  HB2  . SER   B 1 25  ? 18.108  68.506  22.257  1.00 54.08 ? 24  SER   B HB2  1 
ATOM   5051  H  HB3  . SER   B 1 25  ? 17.464  68.753  23.689  1.00 54.08 ? 24  SER   B HB3  1 
ATOM   5052  H  HG   . SER   B 1 25  ? 19.416  69.408  23.974  1.00 59.49 ? 24  SER   B HG   1 
ATOM   5053  N  N    . MET   B 1 26  ? 19.584  65.086  23.847  1.00 41.65 ? 25  MET   B N    1 
ATOM   5054  C  CA   . MET   B 1 26  ? 20.713  64.211  23.526  1.00 41.73 ? 25  MET   B CA   1 
ATOM   5055  C  C    . MET   B 1 26  ? 20.367  62.756  23.851  1.00 46.12 ? 25  MET   B C    1 
ATOM   5056  O  O    . MET   B 1 26  ? 19.485  62.475  24.669  1.00 41.49 ? 25  MET   B O    1 
ATOM   5057  C  CB   . MET   B 1 26  ? 21.992  64.631  24.289  1.00 42.17 ? 25  MET   B CB   1 
ATOM   5058  C  CG   . MET   B 1 26  ? 22.317  66.123  24.217  1.00 40.66 ? 25  MET   B CG   1 
ATOM   5059  S  SD   . MET   B 1 26  ? 23.410  66.599  25.566  1.00 48.19 ? 25  MET   B SD   1 
ATOM   5060  C  CE   . MET   B 1 26  ? 24.836  65.581  25.125  1.00 44.23 ? 25  MET   B CE   1 
ATOM   5061  N  N    . THR   B 1 27  ? 21.088  61.818  23.225  1.00 37.43 ? 26  THR   B N    1 
ATOM   5062  C  CA   . THR   B 1 27  ? 20.901  60.399  23.520  1.00 49.11 ? 26  THR   B CA   1 
ATOM   5063  C  C    . THR   B 1 27  ? 21.512  60.008  24.880  1.00 38.45 ? 26  THR   B C    1 
ATOM   5064  O  O    . THR   B 1 27  ? 22.367  60.696  25.443  1.00 36.23 ? 26  THR   B O    1 
ATOM   5065  C  CB   . THR   B 1 27  ? 21.468  59.491  22.407  1.00 44.57 ? 26  THR   B CB   1 
ATOM   5066  O  OG1  . THR   B 1 27  ? 22.875  59.264  22.595  1.00 55.86 ? 26  THR   B OG1  1 
ATOM   5067  C  CG2  . THR   B 1 27  ? 21.100  59.915  20.962  1.00 57.70 ? 26  THR   B CG2  1 
ATOM   5068  H  H    . THR   B 1 27  ? 21.688  61.980  22.630  1.00 44.91 ? 26  THR   B H    1 
ATOM   5069  H  HA   . THR   B 1 27  ? 19.945  60.240  23.565  1.00 58.93 ? 26  THR   B HA   1 
ATOM   5070  H  HB   . THR   B 1 27  ? 21.023  58.633  22.491  1.00 53.48 ? 26  THR   B HB   1 
ATOM   5071  H  HG1  . THR   B 1 27  ? 23.000  58.514  22.952  1.00 67.03 ? 26  THR   B HG1  1 
ATOM   5072  H  HG21 . THR   B 1 27  ? 21.897  59.931  20.409  1.00 69.24 ? 26  THR   B HG21 1 
ATOM   5073  H  HG22 . THR   B 1 27  ? 20.466  59.286  20.583  1.00 69.24 ? 26  THR   B HG22 1 
ATOM   5074  H  HG23 . THR   B 1 27  ? 20.702  60.799  20.967  1.00 69.24 ? 26  THR   B HG23 1 
ATOM   5075  N  N    . TYR   B 1 28  ? 21.010  58.892  25.426  1.00 43.59 ? 27  TYR   B N    1 
ATOM   5076  C  CA   . TYR   B 1 28  ? 21.536  58.392  26.688  1.00 40.32 ? 27  TYR   B CA   1 
ATOM   5077  C  C    . TYR   B 1 28  ? 23.024  58.110  26.558  1.00 39.09 ? 27  TYR   B C    1 
ATOM   5078  O  O    . TYR   B 1 28  ? 23.822  58.453  27.443  1.00 39.90 ? 27  TYR   B O    1 
ATOM   5079  C  CB   . TYR   B 1 28  ? 20.757  57.139  27.134  1.00 37.35 ? 27  TYR   B CB   1 
ATOM   5080  C  CG   . TYR   B 1 28  ? 19.397  57.450  27.742  1.00 33.59 ? 27  TYR   B CG   1 
ATOM   5081  C  CD1  . TYR   B 1 28  ? 19.298  57.992  29.005  1.00 36.99 ? 27  TYR   B CD1  1 
ATOM   5082  C  CD2  . TYR   B 1 28  ? 18.225  57.179  27.064  1.00 36.69 ? 27  TYR   B CD2  1 
ATOM   5083  C  CE1  . TYR   B 1 28  ? 18.066  58.303  29.559  1.00 33.06 ? 27  TYR   B CE1  1 
ATOM   5084  C  CE2  . TYR   B 1 28  ? 16.989  57.474  27.619  1.00 35.41 ? 27  TYR   B CE2  1 
ATOM   5085  C  CZ   . TYR   B 1 28  ? 16.922  58.030  28.867  1.00 30.29 ? 27  TYR   B CZ   1 
ATOM   5086  O  OH   . TYR   B 1 28  ? 15.688  58.318  29.381  1.00 31.87 ? 27  TYR   B OH   1 
ATOM   5087  H  H    . TYR   B 1 28  ? 20.376  58.419  25.088  1.00 52.30 ? 27  TYR   B H    1 
ATOM   5088  H  HA   . TYR   B 1 28  ? 21.413  59.059  27.382  1.00 48.39 ? 27  TYR   B HA   1 
ATOM   5089  H  HB2  . TYR   B 1 28  ? 20.614  56.569  26.362  1.00 44.82 ? 27  TYR   B HB2  1 
ATOM   5090  H  HB3  . TYR   B 1 28  ? 21.280  56.667  27.801  1.00 44.82 ? 27  TYR   B HB3  1 
ATOM   5091  H  HD1  . TYR   B 1 28  ? 20.071  58.151  29.496  1.00 44.39 ? 27  TYR   B HD1  1 
ATOM   5092  H  HD2  . TYR   B 1 28  ? 18.266  56.790  26.220  1.00 44.03 ? 27  TYR   B HD2  1 
ATOM   5093  H  HE1  . TYR   B 1 28  ? 18.019  58.698  30.400  1.00 39.68 ? 27  TYR   B HE1  1 
ATOM   5094  H  HE2  . TYR   B 1 28  ? 16.209  57.295  27.145  1.00 42.49 ? 27  TYR   B HE2  1 
ATOM   5095  H  HH   . TYR   B 1 28  ? 15.715  58.300  30.221  1.00 38.25 ? 27  TYR   B HH   1 
ATOM   5096  N  N    . GLY   B 1 29  ? 23.434  57.506  25.441  1.00 38.77 ? 28  GLY   B N    1 
ATOM   5097  C  CA   . GLY   B 1 29  ? 24.849  57.251  25.246  1.00 42.63 ? 28  GLY   B CA   1 
ATOM   5098  C  C    . GLY   B 1 29  ? 25.701  58.507  25.225  1.00 44.55 ? 28  GLY   B C    1 
ATOM   5099  O  O    . GLY   B 1 29  ? 26.826  58.502  25.720  1.00 40.28 ? 28  GLY   B O    1 
ATOM   5100  H  H    . GLY   B 1 29  ? 22.924  57.243  24.801  1.00 46.52 ? 28  GLY   B H    1 
ATOM   5101  H  HA2  . GLY   B 1 29  ? 25.169  56.684  25.965  1.00 51.16 ? 28  GLY   B HA2  1 
ATOM   5102  H  HA3  . GLY   B 1 29  ? 24.973  56.790  24.402  1.00 51.16 ? 28  GLY   B HA3  1 
ATOM   5103  N  N    . GLN   B 1 30  ? 25.187  59.598  24.653  1.00 45.74 ? 29  GLN   B N    1 
ATOM   5104  C  CA   . GLN   B 1 30  ? 25.957  60.842  24.672  1.00 46.89 ? 29  GLN   B CA   1 
ATOM   5105  C  C    . GLN   B 1 30  ? 26.180  61.386  26.070  1.00 48.18 ? 29  GLN   B C    1 
ATOM   5106  O  O    . GLN   B 1 30  ? 27.113  62.169  26.266  1.00 48.80 ? 29  GLN   B O    1 
ATOM   5107  C  CB   . GLN   B 1 30  ? 25.267  61.898  23.806  1.00 52.68 ? 29  GLN   B CB   1 
ATOM   5108  C  CG   . GLN   B 1 30  ? 25.604  61.873  22.314  1.00 53.71 ? 29  GLN   B CG   1 
ATOM   5109  C  CD   . GLN   B 1 30  ? 24.573  62.614  21.487  1.00 57.81 ? 29  GLN   B CD   1 
ATOM   5110  O  OE1  . GLN   B 1 30  ? 24.170  63.723  21.820  1.00 65.16 ? 29  GLN   B OE1  1 
ATOM   5111  N  NE2  . GLN   B 1 30  ? 24.278  62.070  20.306  1.00 65.48 ? 29  GLN   B NE2  1 
ATOM   5112  H  H    . GLN   B 1 30  ? 24.423  59.643  24.262  1.00 54.88 ? 29  GLN   B H    1 
ATOM   5113  H  HA   . GLN   B 1 30  ? 26.831  60.660  24.293  1.00 56.27 ? 29  GLN   B HA   1 
ATOM   5114  H  HB2  . GLN   B 1 30  ? 24.308  61.774  23.884  1.00 63.22 ? 29  GLN   B HB2  1 
ATOM   5115  H  HB3  . GLN   B 1 30  ? 25.517  62.773  24.141  1.00 63.22 ? 29  GLN   B HB3  1 
ATOM   5116  H  HG2  . GLN   B 1 30  ? 26.466  62.296  22.175  1.00 64.45 ? 29  GLN   B HG2  1 
ATOM   5117  H  HG3  . GLN   B 1 30  ? 25.634  60.953  22.009  1.00 64.45 ? 29  GLN   B HG3  1 
ATOM   5118  H  HE21 . GLN   B 1 30  ? 24.666  61.344  20.058  1.00 78.58 ? 29  GLN   B HE21 1 
ATOM   5119  H  HE22 . GLN   B 1 30  ? 23.699  62.445  19.792  1.00 78.58 ? 29  GLN   B HE22 1 
ATOM   5120  N  N    . GLN   B 1 31  ? 25.377  60.979  27.044  1.00 43.57 ? 30  GLN   B N    1 
ATOM   5121  C  CA   . GLN   B 1 31  ? 25.458  61.521  28.391  1.00 43.15 ? 30  GLN   B CA   1 
ATOM   5122  C  C    . GLN   B 1 31  ? 26.012  60.533  29.399  1.00 39.24 ? 30  GLN   B C    1 
ATOM   5123  O  O    . GLN   B 1 31  ? 26.699  60.941  30.332  1.00 36.78 ? 30  GLN   B O    1 
ATOM   5124  C  CB   . GLN   B 1 31  ? 24.070  61.985  28.835  1.00 43.64 ? 30  GLN   B CB   1 
ATOM   5125  C  CG   . GLN   B 1 31  ? 23.341  62.702  27.716  1.00 43.35 ? 30  GLN   B CG   1 
ATOM   5126  C  CD   . GLN   B 1 31  ? 21.980  63.216  28.107  1.00 29.25 ? 30  GLN   B CD   1 
ATOM   5127  O  OE1  . GLN   B 1 31  ? 21.831  64.006  29.038  1.00 36.32 ? 30  GLN   B OE1  1 
ATOM   5128  N  NE2  . GLN   B 1 31  ? 20.967  62.758  27.393  1.00 35.52 ? 30  GLN   B NE2  1 
ATOM   5129  H  H    . GLN   B 1 31  ? 24.768  60.379  26.947  1.00 52.29 ? 30  GLN   B H    1 
ATOM   5130  H  HA   . GLN   B 1 31  ? 26.042  62.295  28.400  1.00 51.78 ? 30  GLN   B HA   1 
ATOM   5131  H  HB2  . GLN   B 1 31  ? 23.543  61.215  29.098  1.00 52.37 ? 30  GLN   B HB2  1 
ATOM   5132  H  HB3  . GLN   B 1 31  ? 24.160  62.597  29.582  1.00 52.37 ? 30  GLN   B HB3  1 
ATOM   5133  H  HG2  . GLN   B 1 31  ? 23.873  63.462  27.434  1.00 52.02 ? 30  GLN   B HG2  1 
ATOM   5134  H  HG3  . GLN   B 1 31  ? 23.223  62.087  26.976  1.00 52.02 ? 30  GLN   B HG3  1 
ATOM   5135  H  HE21 . GLN   B 1 31  ? 21.110  62.202  26.752  1.00 42.62 ? 30  GLN   B HE21 1 
ATOM   5136  H  HE22 . GLN   B 1 31  ? 20.166  63.015  27.569  1.00 42.62 ? 30  GLN   B HE22 1 
ATOM   5137  N  N    . PHE   B 1 32  ? 25.762  59.246  29.191  1.00 36.55 ? 31  PHE   B N    1 
ATOM   5138  C  CA   . PHE   B 1 32  ? 26.097  58.208  30.151  1.00 42.67 ? 31  PHE   B CA   1 
ATOM   5139  C  C    . PHE   B 1 32  ? 27.053  57.150  29.619  1.00 36.66 ? 31  PHE   B C    1 
ATOM   5140  O  O    . PHE   B 1 32  ? 27.601  56.385  30.415  1.00 40.64 ? 31  PHE   B O    1 
ATOM   5141  C  CB   . PHE   B 1 32  ? 24.825  57.468  30.592  1.00 41.84 ? 31  PHE   B CB   1 
ATOM   5142  C  CG   . PHE   B 1 32  ? 23.857  58.296  31.364  1.00 33.87 ? 31  PHE   B CG   1 
ATOM   5143  C  CD1  . PHE   B 1 32  ? 24.273  59.395  32.097  1.00 43.40 ? 31  PHE   B CD1  1 
ATOM   5144  C  CD2  . PHE   B 1 32  ? 22.516  57.943  31.390  1.00 41.78 ? 31  PHE   B CD2  1 
ATOM   5145  C  CE1  . PHE   B 1 32  ? 23.363  60.140  32.825  1.00 40.43 ? 31  PHE   B CE1  1 
ATOM   5146  C  CE2  . PHE   B 1 32  ? 21.599  58.686  32.125  1.00 43.63 ? 31  PHE   B CE2  1 
ATOM   5147  C  CZ   . PHE   B 1 32  ? 22.025  59.786  32.833  1.00 41.92 ? 31  PHE   B CZ   1 
ATOM   5148  H  H    . PHE   B 1 32  ? 25.387  58.941  28.480  1.00 43.86 ? 31  PHE   B H    1 
ATOM   5149  H  HA   . PHE   B 1 32  ? 26.506  58.635  30.920  1.00 51.20 ? 31  PHE   B HA   1 
ATOM   5150  H  HB2  . PHE   B 1 32  ? 24.367  57.145  29.800  1.00 50.21 ? 31  PHE   B HB2  1 
ATOM   5151  H  HB3  . PHE   B 1 32  ? 25.083  56.720  31.154  1.00 50.21 ? 31  PHE   B HB3  1 
ATOM   5152  H  HD1  . PHE   B 1 32  ? 25.172  59.634  32.100  1.00 52.08 ? 31  PHE   B HD1  1 
ATOM   5153  H  HD2  . PHE   B 1 32  ? 22.227  57.201  30.910  1.00 50.13 ? 31  PHE   B HD2  1 
ATOM   5154  H  HE1  . PHE   B 1 32  ? 23.650  60.879  33.310  1.00 48.52 ? 31  PHE   B HE1  1 
ATOM   5155  H  HE2  . PHE   B 1 32  ? 20.702  58.441  32.138  1.00 52.35 ? 31  PHE   B HE2  1 
ATOM   5156  H  HZ   . PHE   B 1 32  ? 21.414  60.291  33.318  1.00 50.31 ? 31  PHE   B HZ   1 
ATOM   5157  N  N    . GLY   B 1 33  ? 27.226  57.041  28.311  1.00 38.11 ? 32  GLY   B N    1 
ATOM   5158  C  CA   . GLY   B 1 33  ? 27.834  55.861  27.749  1.00 41.04 ? 32  GLY   B CA   1 
ATOM   5159  C  C    . GLY   B 1 33  ? 26.773  54.794  27.598  1.00 38.13 ? 32  GLY   B C    1 
ATOM   5160  O  O    . GLY   B 1 33  ? 25.572  55.086  27.638  1.00 38.49 ? 32  GLY   B O    1 
ATOM   5161  H  H    . GLY   B 1 33  ? 26.998  57.638  27.735  1.00 45.73 ? 32  GLY   B H    1 
ATOM   5162  H  HA2  . GLY   B 1 33  ? 28.215  56.061  26.880  1.00 49.24 ? 32  GLY   B HA2  1 
ATOM   5163  H  HA3  . GLY   B 1 33  ? 28.537  55.535  28.334  1.00 49.24 ? 32  GLY   B HA3  1 
ATOM   5164  N  N    . PRO   B 1 34  ? 27.182  53.539  27.438  1.00 36.52 ? 33  PRO   B N    1 
ATOM   5165  C  CA   . PRO   B 1 34  ? 26.192  52.466  27.269  1.00 36.23 ? 33  PRO   B CA   1 
ATOM   5166  C  C    . PRO   B 1 34  ? 25.187  52.489  28.411  1.00 34.87 ? 33  PRO   B C    1 
ATOM   5167  O  O    . PRO   B 1 34  ? 25.563  52.581  29.581  1.00 34.15 ? 33  PRO   B O    1 
ATOM   5168  C  CB   . PRO   B 1 34  ? 27.047  51.194  27.289  1.00 40.67 ? 33  PRO   B CB   1 
ATOM   5169  C  CG   . PRO   B 1 34  ? 28.366  51.635  26.712  1.00 44.30 ? 33  PRO   B CG   1 
ATOM   5170  C  CD   . PRO   B 1 34  ? 28.564  53.050  27.251  1.00 45.67 ? 33  PRO   B CD   1 
ATOM   5171  H  HA   . PRO   B 1 34  ? 25.735  52.535  26.417  1.00 43.47 ? 33  PRO   B HA   1 
ATOM   5172  H  HB2  . PRO   B 1 34  ? 27.152  50.876  28.199  1.00 48.80 ? 33  PRO   B HB2  1 
ATOM   5173  H  HB3  . PRO   B 1 34  ? 26.637  50.507  26.742  1.00 48.80 ? 33  PRO   B HB3  1 
ATOM   5174  H  HG2  . PRO   B 1 34  ? 29.075  51.045  27.012  1.00 53.16 ? 33  PRO   B HG2  1 
ATOM   5175  H  HG3  . PRO   B 1 34  ? 28.322  51.634  25.743  1.00 53.16 ? 33  PRO   B HG3  1 
ATOM   5176  H  HD2  . PRO   B 1 34  ? 29.042  53.034  28.095  1.00 54.81 ? 33  PRO   B HD2  1 
ATOM   5177  H  HD3  . PRO   B 1 34  ? 29.042  53.600  26.610  1.00 54.81 ? 33  PRO   B HD3  1 
ATOM   5178  N  N    . THR   B 1 35  ? 23.905  52.427  28.060  1.00 31.04 ? 34  THR   B N    1 
ATOM   5179  C  CA   . THR   B 1 35  ? 22.804  52.603  28.998  1.00 34.74 ? 34  THR   B CA   1 
ATOM   5180  C  C    . THR   B 1 35  ? 21.698  51.610  28.673  1.00 39.07 ? 34  THR   B C    1 
ATOM   5181  O  O    . THR   B 1 35  ? 21.393  51.373  27.504  1.00 36.64 ? 34  THR   B O    1 
ATOM   5182  C  CB   . THR   B 1 35  ? 22.249  54.040  28.941  1.00 32.58 ? 34  THR   B CB   1 
ATOM   5183  O  OG1  . THR   B 1 35  ? 23.318  54.965  29.145  1.00 30.75 ? 34  THR   B OG1  1 
ATOM   5184  C  CG2  . THR   B 1 35  ? 21.187  54.258  29.991  1.00 30.96 ? 34  THR   B CG2  1 
ATOM   5185  H  H    . THR   B 1 35  ? 23.640  52.280  27.255  1.00 37.25 ? 34  THR   B H    1 
ATOM   5186  H  HA   . THR   B 1 35  ? 23.113  52.426  29.900  1.00 41.69 ? 34  THR   B HA   1 
ATOM   5187  H  HB   . THR   B 1 35  ? 21.842  54.193  28.074  1.00 39.10 ? 34  THR   B HB   1 
ATOM   5188  H  HG1  . THR   B 1 35  ? 23.404  55.457  28.469  1.00 36.90 ? 34  THR   B HG1  1 
ATOM   5189  H  HG21 . THR   B 1 35  ? 21.226  55.170  30.318  1.00 37.15 ? 34  THR   B HG21 1 
ATOM   5190  H  HG22 . THR   B 1 35  ? 20.309  54.096  29.612  1.00 37.15 ? 34  THR   B HG22 1 
ATOM   5191  H  HG23 . THR   B 1 35  ? 21.326  53.650  30.734  1.00 37.15 ? 34  THR   B HG23 1 
ATOM   5192  N  N    . TYR   B 1 36  ? 21.088  51.040  29.716  1.00 28.21 ? 35  TYR   B N    1 
ATOM   5193  C  CA   . TYR   B 1 36  ? 20.086  50.008  29.537  1.00 23.27 ? 35  TYR   B CA   1 
ATOM   5194  C  C    . TYR   B 1 36  ? 18.878  50.260  30.421  1.00 31.95 ? 35  TYR   B C    1 
ATOM   5195  O  O    . TYR   B 1 36  ? 19.007  50.732  31.555  1.00 26.20 ? 35  TYR   B O    1 
ATOM   5196  C  CB   . TYR   B 1 36  ? 20.659  48.612  29.841  1.00 28.55 ? 35  TYR   B CB   1 
ATOM   5197  C  CG   . TYR   B 1 36  ? 21.933  48.266  29.095  1.00 31.05 ? 35  TYR   B CG   1 
ATOM   5198  C  CD1  . TYR   B 1 36  ? 23.165  48.710  29.534  1.00 28.87 ? 35  TYR   B CD1  1 
ATOM   5199  C  CD2  . TYR   B 1 36  ? 21.899  47.489  27.944  1.00 34.97 ? 35  TYR   B CD2  1 
ATOM   5200  C  CE1  . TYR   B 1 36  ? 24.328  48.388  28.855  1.00 31.37 ? 35  TYR   B CE1  1 
ATOM   5201  C  CE2  . TYR   B 1 36  ? 23.052  47.164  27.275  1.00 31.42 ? 35  TYR   B CE2  1 
ATOM   5202  C  CZ   . TYR   B 1 36  ? 24.253  47.624  27.722  1.00 30.85 ? 35  TYR   B CZ   1 
ATOM   5203  O  OH   . TYR   B 1 36  ? 25.399  47.298  27.040  1.00 42.38 ? 35  TYR   B OH   1 
ATOM   5204  H  H    . TYR   B 1 36  ? 21.243  51.240  30.537  1.00 33.85 ? 35  TYR   B H    1 
ATOM   5205  H  HA   . TYR   B 1 36  ? 19.781  50.037  28.617  1.00 27.92 ? 35  TYR   B HA   1 
ATOM   5206  H  HB2  . TYR   B 1 36  ? 20.855  48.561  30.790  1.00 34.26 ? 35  TYR   B HB2  1 
ATOM   5207  H  HB3  . TYR   B 1 36  ? 19.993  47.948  29.603  1.00 34.26 ? 35  TYR   B HB3  1 
ATOM   5208  H  HD1  . TYR   B 1 36  ? 23.215  49.235  30.301  1.00 34.65 ? 35  TYR   B HD1  1 
ATOM   5209  H  HD2  . TYR   B 1 36  ? 21.081  47.185  27.621  1.00 41.97 ? 35  TYR   B HD2  1 
ATOM   5210  H  HE1  . TYR   B 1 36  ? 25.152  48.688  29.166  1.00 37.64 ? 35  TYR   B HE1  1 
ATOM   5211  H  HE2  . TYR   B 1 36  ? 23.013  46.628  26.516  1.00 37.70 ? 35  TYR   B HE2  1 
ATOM   5212  H  HH   . TYR   B 1 36  ? 26.061  47.677  27.392  1.00 50.85 ? 35  TYR   B HH   1 
ATOM   5213  N  N    . LEU   B 1 37  ? 17.708  49.929  29.893  1.00 29.86 ? 36  LEU   B N    1 
ATOM   5214  C  CA   . LEU   B 1 37  ? 16.448  50.038  30.613  1.00 32.30 ? 36  LEU   B CA   1 
ATOM   5215  C  C    . LEU   B 1 37  ? 15.808  48.662  30.660  1.00 35.10 ? 36  LEU   B C    1 
ATOM   5216  O  O    . LEU   B 1 37  ? 15.324  48.164  29.637  1.00 32.30 ? 36  LEU   B O    1 
ATOM   5217  C  CB   . LEU   B 1 37  ? 15.510  51.032  29.942  1.00 31.78 ? 36  LEU   B CB   1 
ATOM   5218  C  CG   . LEU   B 1 37  ? 14.251  51.353  30.731  1.00 32.24 ? 36  LEU   B CG   1 
ATOM   5219  C  CD1  . LEU   B 1 37  ? 14.588  51.870  32.111  1.00 32.11 ? 36  LEU   B CD1  1 
ATOM   5220  C  CD2  . LEU   B 1 37  ? 13.421  52.360  29.964  1.00 31.63 ? 36  LEU   B CD2  1 
ATOM   5221  H  H    . LEU   B 1 37  ? 17.616  49.629  29.093  1.00 35.84 ? 36  LEU   B H    1 
ATOM   5222  H  HA   . LEU   B 1 37  ? 16.627  50.340  31.518  1.00 38.75 ? 36  LEU   B HA   1 
ATOM   5223  H  HB2  . LEU   B 1 37  ? 15.990  51.864  29.806  1.00 38.13 ? 36  LEU   B HB2  1 
ATOM   5224  H  HB3  . LEU   B 1 37  ? 15.234  50.664  29.088  1.00 38.13 ? 36  LEU   B HB3  1 
ATOM   5225  H  HG   . LEU   B 1 37  ? 13.730  50.544  30.851  1.00 38.69 ? 36  LEU   B HG   1 
ATOM   5226  H  HD11 . LEU   B 1 37  ? 14.760  51.116  32.697  1.00 38.53 ? 36  LEU   B HD11 1 
ATOM   5227  H  HD12 . LEU   B 1 37  ? 15.377  52.432  32.054  1.00 38.53 ? 36  LEU   B HD12 1 
ATOM   5228  H  HD13 . LEU   B 1 37  ? 13.838  52.385  32.447  1.00 38.53 ? 36  LEU   B HD13 1 
ATOM   5229  H  HD21 . LEU   B 1 37  ? 13.413  53.199  30.451  1.00 37.96 ? 36  LEU   B HD21 1 
ATOM   5230  H  HD22 . LEU   B 1 37  ? 13.813  52.490  29.086  1.00 37.96 ? 36  LEU   B HD22 1 
ATOM   5231  H  HD23 . LEU   B 1 37  ? 12.516  52.021  29.875  1.00 37.96 ? 36  LEU   B HD23 1 
ATOM   5232  N  N    . ASP   B 1 38  ? 15.771  48.068  31.848  1.00 33.45 ? 37  ASP   B N    1 
ATOM   5233  C  CA   . ASP   B 1 38  ? 15.242  46.719  32.017  1.00 39.62 ? 37  ASP   B CA   1 
ATOM   5234  C  C    . ASP   B 1 38  ? 15.798  45.773  30.953  1.00 31.90 ? 37  ASP   B C    1 
ATOM   5235  O  O    . ASP   B 1 38  ? 15.073  44.974  30.366  1.00 31.64 ? 37  ASP   B O    1 
ATOM   5236  C  CB   . ASP   B 1 38  ? 13.719  46.730  31.972  1.00 38.20 ? 37  ASP   B CB   1 
ATOM   5237  C  CG   . ASP   B 1 38  ? 13.096  46.974  33.331  1.00 56.81 ? 37  ASP   B CG   1 
ATOM   5238  O  OD1  . ASP   B 1 38  ? 12.182  46.202  33.711  1.00 65.51 ? 37  ASP   B OD1  1 
ATOM   5239  O  OD2  . ASP   B 1 38  ? 13.517  47.925  34.025  1.00 63.84 ? 37  ASP   B OD2  1 
ATOM   5240  H  H    . ASP   B 1 38  ? 16.049  48.428  32.577  1.00 40.14 ? 37  ASP   B H    1 
ATOM   5241  H  HA   . ASP   B 1 38  ? 15.523  46.388  32.884  1.00 47.54 ? 37  ASP   B HA   1 
ATOM   5242  H  HB2  . ASP   B 1 38  ? 13.425  47.437  31.376  1.00 45.84 ? 37  ASP   B HB2  1 
ATOM   5243  H  HB3  . ASP   B 1 38  ? 13.406  45.871  31.648  1.00 45.84 ? 37  ASP   B HB3  1 
ATOM   5244  N  N    . GLY   B 1 39  ? 17.099  45.865  30.709  1.00 27.23 ? 38  GLY   B N    1 
ATOM   5245  C  CA   . GLY   B 1 39  ? 17.769  44.982  29.789  1.00 31.30 ? 38  GLY   B CA   1 
ATOM   5246  C  C    . GLY   B 1 39  ? 17.877  45.520  28.382  1.00 31.49 ? 38  GLY   B C    1 
ATOM   5247  O  O    . GLY   B 1 39  ? 18.827  45.175  27.668  1.00 31.73 ? 38  GLY   B O    1 
ATOM   5248  H  H    . GLY   B 1 39  ? 17.617  46.446  31.074  1.00 32.67 ? 38  GLY   B H    1 
ATOM   5249  H  HA2  . GLY   B 1 39  ? 18.667  44.814  30.115  1.00 37.56 ? 38  GLY   B HA2  1 
ATOM   5250  H  HA3  . GLY   B 1 39  ? 17.285  44.142  29.752  1.00 37.56 ? 38  GLY   B HA3  1 
ATOM   5251  N  N    . ALA   B 1 40  ? 16.945  46.379  27.974  1.00 31.46 ? 39  ALA   B N    1 
ATOM   5252  C  CA   . ALA   B 1 40  ? 16.988  46.946  26.629  1.00 35.38 ? 39  ALA   B CA   1 
ATOM   5253  C  C    . ALA   B 1 40  ? 18.117  47.961  26.482  1.00 33.72 ? 39  ALA   B C    1 
ATOM   5254  O  O    . ALA   B 1 40  ? 18.324  48.820  27.343  1.00 31.41 ? 39  ALA   B O    1 
ATOM   5255  C  CB   . ALA   B 1 40  ? 15.662  47.631  26.301  1.00 35.27 ? 39  ALA   B CB   1 
ATOM   5256  H  H    . ALA   B 1 40  ? 16.283  46.647  28.453  1.00 37.75 ? 39  ALA   B H    1 
ATOM   5257  H  HA   . ALA   B 1 40  ? 17.142  46.224  25.999  1.00 42.45 ? 39  ALA   B HA   1 
ATOM   5258  H  HB1  . ALA   B 1 40  ? 15.625  47.811  25.349  1.00 42.33 ? 39  ALA   B HB1  1 
ATOM   5259  H  HB2  . ALA   B 1 40  ? 14.932  47.045  26.556  1.00 42.33 ? 39  ALA   B HB2  1 
ATOM   5260  H  HB3  . ALA   B 1 40  ? 15.606  48.464  26.797  1.00 42.33 ? 39  ALA   B HB3  1 
ATOM   5261  N  N    . ASP   B 1 41  ? 18.815  47.902  25.349  1.00 34.67 ? 40  ASP   B N    1 
ATOM   5262  C  CA   . ASP   B 1 41  ? 19.900  48.839  25.059  1.00 36.45 ? 40  ASP   B CA   1 
ATOM   5263  C  C    . ASP   B 1 41  ? 19.314  50.165  24.577  1.00 40.83 ? 40  ASP   B C    1 
ATOM   5264  O  O    . ASP   B 1 41  ? 18.698  50.225  23.508  1.00 37.28 ? 40  ASP   B O    1 
ATOM   5265  C  CB   . ASP   B 1 41  ? 20.836  48.264  23.997  1.00 35.77 ? 40  ASP   B CB   1 
ATOM   5266  C  CG   . ASP   B 1 41  ? 22.113  49.048  23.870  1.00 35.25 ? 40  ASP   B CG   1 
ATOM   5267  O  OD1  . ASP   B 1 41  ? 22.105  50.251  24.192  1.00 37.81 ? 40  ASP   B OD1  1 
ATOM   5268  O  OD2  . ASP   B 1 41  ? 23.125  48.473  23.434  1.00 42.15 ? 40  ASP   B OD2  1 
ATOM   5269  H  H    . ASP   B 1 41  ? 18.679  47.324  24.727  1.00 41.61 ? 40  ASP   B H    1 
ATOM   5270  H  HA   . ASP   B 1 41  ? 20.402  48.994  25.874  1.00 43.74 ? 40  ASP   B HA   1 
ATOM   5271  H  HB2  . ASP   B 1 41  ? 21.064  47.352  24.236  1.00 42.92 ? 40  ASP   B HB2  1 
ATOM   5272  H  HB3  . ASP   B 1 41  ? 20.387  48.279  23.137  1.00 42.92 ? 40  ASP   B HB3  1 
ATOM   5273  N  N    . VAL   B 1 42  ? 19.488  51.233  25.357  1.00 36.23 ? 41  VAL   B N    1 
ATOM   5274  C  CA   . VAL   B 1 42  ? 18.939  52.539  25.004  1.00 38.90 ? 41  VAL   B CA   1 
ATOM   5275  C  C    . VAL   B 1 42  ? 20.045  53.564  24.735  1.00 36.56 ? 41  VAL   B C    1 
ATOM   5276  O  O    . VAL   B 1 42  ? 19.797  54.759  24.751  1.00 35.33 ? 41  VAL   B O    1 
ATOM   5277  C  CB   . VAL   B 1 42  ? 17.973  53.042  26.100  1.00 40.68 ? 41  VAL   B CB   1 
ATOM   5278  C  CG1  . VAL   B 1 42  ? 16.774  52.106  26.234  1.00 36.81 ? 41  VAL   B CG1  1 
ATOM   5279  C  CG2  . VAL   B 1 42  ? 18.686  53.184  27.464  1.00 36.11 ? 41  VAL   B CG2  1 
ATOM   5280  H  H    . VAL   B 1 42  ? 19.922  51.224  26.099  1.00 43.48 ? 41  VAL   B H    1 
ATOM   5281  H  HA   . VAL   B 1 42  ? 18.437  52.436  24.180  1.00 46.68 ? 41  VAL   B HA   1 
ATOM   5282  H  HB   . VAL   B 1 42  ? 17.658  53.920  25.834  1.00 48.82 ? 41  VAL   B HB   1 
ATOM   5283  H  HG11 . VAL   B 1 42  ? 16.038  52.592  26.638  1.00 44.17 ? 41  VAL   B HG11 1 
ATOM   5284  H  HG12 . VAL   B 1 42  ? 16.518  51.792  25.352  1.00 44.17 ? 41  VAL   B HG12 1 
ATOM   5285  H  HG13 . VAL   B 1 42  ? 17.021  51.354  26.794  1.00 44.17 ? 41  VAL   B HG13 1 
ATOM   5286  H  HG21 . VAL   B 1 42  ? 18.153  53.752  28.041  1.00 43.33 ? 41  VAL   B HG21 1 
ATOM   5287  H  HG22 . VAL   B 1 42  ? 18.783  52.305  27.862  1.00 43.33 ? 41  VAL   B HG22 1 
ATOM   5288  H  HG23 . VAL   B 1 42  ? 19.560  53.582  27.323  1.00 43.33 ? 41  VAL   B HG23 1 
ATOM   5289  N  N    . THR   B 1 43  ? 21.261  53.089  24.455  1.00 36.32 ? 42  THR   B N    1 
ATOM   5290  C  CA   . THR   B 1 43  ? 22.408  53.957  24.272  1.00 38.59 ? 42  THR   B CA   1 
ATOM   5291  C  C    . THR   B 1 43  ? 22.232  54.947  23.125  1.00 45.55 ? 42  THR   B C    1 
ATOM   5292  O  O    . THR   B 1 43  ? 22.899  55.991  23.122  1.00 48.03 ? 42  THR   B O    1 
ATOM   5293  C  CB   . THR   B 1 43  ? 23.659  53.118  24.017  1.00 41.91 ? 42  THR   B CB   1 
ATOM   5294  O  OG1  . THR   B 1 43  ? 23.757  52.048  24.976  1.00 44.11 ? 42  THR   B OG1  1 
ATOM   5295  C  CG2  . THR   B 1 43  ? 24.916  53.986  24.042  1.00 47.34 ? 42  THR   B CG2  1 
ATOM   5296  H  H    . THR   B 1 43  ? 21.445  52.254  24.367  1.00 43.58 ? 42  THR   B H    1 
ATOM   5297  H  HA   . THR   B 1 43  ? 22.528  54.466  25.088  1.00 46.30 ? 42  THR   B HA   1 
ATOM   5298  H  HB   . THR   B 1 43  ? 23.598  52.723  23.133  1.00 50.29 ? 42  THR   B HB   1 
ATOM   5299  H  HG1  . THR   B 1 43  ? 24.451  51.597  24.834  1.00 52.93 ? 42  THR   B HG1  1 
ATOM   5300  H  HG21 . THR   B 1 43  ? 25.689  53.443  24.261  1.00 56.81 ? 42  THR   B HG21 1 
ATOM   5301  H  HG22 . THR   B 1 43  ? 25.054  54.395  23.174  1.00 56.81 ? 42  THR   B HG22 1 
ATOM   5302  H  HG23 . THR   B 1 43  ? 24.823  54.685  24.708  1.00 56.81 ? 42  THR   B HG23 1 
ATOM   5303  N  N    . LYS   B 1 44  ? 21.425  54.610  22.115  1.00 46.20 ? 43  LYS   B N    1 
ATOM   5304  C  CA   . LYS   B 1 44  ? 21.270  55.467  20.948  1.00 54.16 ? 43  LYS   B CA   1 
ATOM   5305  C  C    . LYS   B 1 44  ? 19.940  56.195  20.924  1.00 56.49 ? 43  LYS   B C    1 
ATOM   5306  O  O    . LYS   B 1 44  ? 19.737  57.045  20.051  1.00 62.49 ? 43  LYS   B O    1 
ATOM   5307  C  CB   . LYS   B 1 44  ? 21.386  54.649  19.655  1.00 52.36 ? 43  LYS   B CB   1 
ATOM   5308  C  CG   . LYS   B 1 44  ? 22.416  53.537  19.720  1.00 51.21 ? 43  LYS   B CG   1 
ATOM   5309  C  CD   . LYS   B 1 44  ? 23.808  53.980  20.117  1.00 64.34 ? 43  LYS   B CD   1 
ATOM   5310  C  CE   . LYS   B 1 44  ? 24.854  53.023  19.538  1.00 67.18 ? 43  LYS   B CE   1 
ATOM   5311  N  NZ   . LYS   B 1 44  ? 25.230  53.410  18.145  1.00 66.81 ? 43  LYS   B NZ   1 
ATOM   5312  H  H    . LYS   B 1 44  ? 20.959  53.887  22.086  1.00 55.44 ? 43  LYS   B H    1 
ATOM   5313  H  HA   . LYS   B 1 44  ? 21.987  56.121  20.955  1.00 65.00 ? 43  LYS   B HA   1 
ATOM   5314  H  HB2  . LYS   B 1 44  ? 20.526  54.243  19.465  1.00 62.83 ? 43  LYS   B HB2  1 
ATOM   5315  H  HB3  . LYS   B 1 44  ? 21.639  55.244  18.932  1.00 62.83 ? 43  LYS   B HB3  1 
ATOM   5316  H  HG2  . LYS   B 1 44  ? 22.123  52.883  20.373  1.00 61.45 ? 43  LYS   B HG2  1 
ATOM   5317  H  HG3  . LYS   B 1 44  ? 22.482  53.126  18.844  1.00 61.45 ? 43  LYS   B HG3  1 
ATOM   5318  H  HD2  . LYS   B 1 44  ? 23.977  54.871  19.772  1.00 77.21 ? 43  LYS   B HD2  1 
ATOM   5319  H  HD3  . LYS   B 1 44  ? 23.887  53.978  21.084  1.00 77.21 ? 43  LYS   B HD3  1 
ATOM   5320  H  HE2  . LYS   B 1 44  ? 25.652  53.047  20.089  1.00 80.61 ? 43  LYS   B HE2  1 
ATOM   5321  H  HE3  . LYS   B 1 44  ? 24.491  52.124  19.519  1.00 80.61 ? 43  LYS   B HE3  1 
ATOM   5322  H  HZ1  . LYS   B 1 44  ? 25.884  52.884  17.849  1.00 80.17 ? 43  LYS   B HZ1  1 
ATOM   5323  H  HZ2  . LYS   B 1 44  ? 24.527  53.327  17.605  1.00 80.17 ? 43  LYS   B HZ2  1 
ATOM   5324  H  HZ3  . LYS   B 1 44  ? 25.509  54.255  18.128  1.00 80.17 ? 43  LYS   B HZ3  1 
ATOM   5325  N  N    . ILE   B 1 45  ? 19.049  55.930  21.885  1.00 61.81 ? 44  ILE   B N    1 
ATOM   5326  C  CA   . ILE   B 1 45  ? 17.716  56.507  21.915  1.00 51.31 ? 44  ILE   B CA   1 
ATOM   5327  C  C    . ILE   B 1 45  ? 17.798  57.720  22.832  1.00 53.83 ? 44  ILE   B C    1 
ATOM   5328  O  O    . ILE   B 1 45  ? 18.643  57.794  23.729  1.00 59.25 ? 44  ILE   B O    1 
ATOM   5329  C  CB   . ILE   B 1 45  ? 16.649  55.484  22.370  1.00 55.54 ? 44  ILE   B CB   1 
ATOM   5330  C  CG1  . ILE   B 1 45  ? 16.495  55.500  23.888  1.00 58.06 ? 44  ILE   B CG1  1 
ATOM   5331  C  CG2  . ILE   B 1 45  ? 16.974  54.074  21.858  1.00 55.14 ? 44  ILE   B CG2  1 
ATOM   5332  C  CD1  . ILE   B 1 45  ? 15.411  54.562  24.421  1.00 60.01 ? 44  ILE   B CD1  1 
ATOM   5333  H  H    . ILE   B 1 45  ? 19.204  55.402  22.546  1.00 74.17 ? 44  ILE   B H    1 
ATOM   5334  H  HA   . ILE   B 1 45  ? 17.446  56.787  21.027  1.00 61.57 ? 44  ILE   B HA   1 
ATOM   5335  H  HB   . ILE   B 1 45  ? 15.801  55.749  21.981  1.00 66.65 ? 44  ILE   B HB   1 
ATOM   5336  H  HG12 . ILE   B 1 45  ? 17.338  55.231  24.287  1.00 69.67 ? 44  ILE   B HG12 1 
ATOM   5337  H  HG13 . ILE   B 1 45  ? 16.268  56.400  24.167  1.00 69.67 ? 44  ILE   B HG13 1 
ATOM   5338  H  HG21 . ILE   B 1 45  ? 16.286  53.461  22.161  1.00 66.17 ? 44  ILE   B HG21 1 
ATOM   5339  H  HG22 . ILE   B 1 45  ? 17.000  54.088  20.888  1.00 66.17 ? 44  ILE   B HG22 1 
ATOM   5340  H  HG23 . ILE   B 1 45  ? 17.837  53.802  22.208  1.00 66.17 ? 44  ILE   B HG23 1 
ATOM   5341  H  HD11 . ILE   B 1 45  ? 15.379  54.632  25.388  1.00 72.02 ? 44  ILE   B HD11 1 
ATOM   5342  H  HD12 . ILE   B 1 45  ? 14.556  54.820  24.043  1.00 72.02 ? 44  ILE   B HD12 1 
ATOM   5343  H  HD13 . ILE   B 1 45  ? 15.625  53.652  24.163  1.00 72.02 ? 44  ILE   B HD13 1 
ATOM   5344  N  N    . LYS   B 1 46  ? 16.971  58.706  22.560  1.00 48.53 ? 45  LYS   B N    1 
ATOM   5345  C  CA   . LYS   B 1 46  ? 16.892  59.921  23.337  1.00 48.64 ? 45  LYS   B CA   1 
ATOM   5346  C  C    . LYS   B 1 46  ? 15.850  59.775  24.442  1.00 41.41 ? 45  LYS   B C    1 
ATOM   5347  O  O    . LYS   B 1 46  ? 14.914  58.984  24.319  1.00 43.10 ? 45  LYS   B O    1 
ATOM   5348  C  CB   . LYS   B 1 46  ? 16.557  61.099  22.425  1.00 51.45 ? 45  LYS   B CB   1 
ATOM   5349  C  CG   . LYS   B 1 46  ? 17.753  61.464  21.525  1.00 51.64 ? 45  LYS   B CG   1 
ATOM   5350  C  CD   . LYS   B 1 46  ? 17.558  62.766  20.788  1.00 53.92 ? 45  LYS   B CD   1 
ATOM   5351  C  CE   . LYS   B 1 46  ? 16.153  62.845  20.213  1.00 58.69 ? 45  LYS   B CE   1 
ATOM   5352  N  NZ   . LYS   B 1 46  ? 16.105  63.806  19.056  1.00 63.81 ? 45  LYS   B NZ   1 
ATOM   5353  H  H    . LYS   B 1 46  ? 16.419  58.698  21.900  1.00 58.23 ? 45  LYS   B H    1 
ATOM   5354  H  HA   . LYS   B 1 46  ? 17.742  60.113  23.763  1.00 58.36 ? 45  LYS   B HA   1 
ATOM   5355  H  HB2  . LYS   B 1 46  ? 15.807  60.862  21.857  1.00 61.73 ? 45  LYS   B HB2  1 
ATOM   5356  H  HB3  . LYS   B 1 46  ? 16.333  61.872  22.966  1.00 61.73 ? 45  LYS   B HB3  1 
ATOM   5357  H  HG2  . LYS   B 1 46  ? 18.548  61.548  22.075  1.00 61.97 ? 45  LYS   B HG2  1 
ATOM   5358  H  HG3  . LYS   B 1 46  ? 17.878  60.763  20.866  1.00 61.97 ? 45  LYS   B HG3  1 
ATOM   5359  H  HD2  . LYS   B 1 46  ? 17.684  63.508  21.400  1.00 64.71 ? 45  LYS   B HD2  1 
ATOM   5360  H  HD3  . LYS   B 1 46  ? 18.195  62.825  20.059  1.00 64.71 ? 45  LYS   B HD3  1 
ATOM   5361  H  HE2  . LYS   B 1 46  ? 15.882  61.969  19.897  1.00 70.42 ? 45  LYS   B HE2  1 
ATOM   5362  H  HE3  . LYS   B 1 46  ? 15.540  63.156  20.897  1.00 70.42 ? 45  LYS   B HE3  1 
ATOM   5363  H  HZ1  . LYS   B 1 46  ? 16.780  63.645  18.498  1.00 76.57 ? 45  LYS   B HZ1  1 
ATOM   5364  H  HZ2  . LYS   B 1 46  ? 15.338  63.712  18.615  1.00 76.57 ? 45  LYS   B HZ2  1 
ATOM   5365  H  HZ3  . LYS   B 1 46  ? 16.168  64.642  19.352  1.00 76.57 ? 45  LYS   B HZ3  1 
ATOM   5366  N  N    . PRO   B 1 47  ? 15.988  60.487  25.553  1.00 39.25 ? 46  PRO   B N    1 
ATOM   5367  C  CA   . PRO   B 1 47  ? 15.005  60.351  26.642  1.00 33.67 ? 46  PRO   B CA   1 
ATOM   5368  C  C    . PRO   B 1 47  ? 13.566  60.596  26.194  1.00 42.83 ? 46  PRO   B C    1 
ATOM   5369  O  O    . PRO   B 1 47  ? 13.291  61.456  25.359  1.00 45.70 ? 46  PRO   B O    1 
ATOM   5370  C  CB   . PRO   B 1 47  ? 15.469  61.406  27.657  1.00 37.22 ? 46  PRO   B CB   1 
ATOM   5371  C  CG   . PRO   B 1 47  ? 16.960  61.479  27.441  1.00 37.79 ? 46  PRO   B CG   1 
ATOM   5372  C  CD   . PRO   B 1 47  ? 17.118  61.357  25.947  1.00 38.53 ? 46  PRO   B CD   1 
ATOM   5373  H  HA   . PRO   B 1 47  ? 15.060  59.461  27.022  1.00 40.40 ? 46  PRO   B HA   1 
ATOM   5374  H  HB2  . PRO   B 1 47  ? 15.044  62.258  27.472  1.00 44.67 ? 46  PRO   B HB2  1 
ATOM   5375  H  HB3  . PRO   B 1 47  ? 15.258  61.118  28.559  1.00 44.67 ? 46  PRO   B HB3  1 
ATOM   5376  H  HG2  . PRO   B 1 47  ? 17.303  62.328  27.761  1.00 45.35 ? 46  PRO   B HG2  1 
ATOM   5377  H  HG3  . PRO   B 1 47  ? 17.401  60.748  27.900  1.00 45.35 ? 46  PRO   B HG3  1 
ATOM   5378  H  HD2  . PRO   B 1 47  ? 17.049  62.226  25.521  1.00 46.24 ? 46  PRO   B HD2  1 
ATOM   5379  H  HD3  . PRO   B 1 47  ? 17.966  60.944  25.723  1.00 46.24 ? 46  PRO   B HD3  1 
ATOM   5380  N  N    . HIS   B 1 48  ? 12.643  59.810  26.753  1.00 40.57 ? 47  HIS   B N    1 
ATOM   5381  C  CA   . HIS   B 1 48  ? 11.208  59.983  26.548  1.00 41.54 ? 47  HIS   B CA   1 
ATOM   5382  C  C    . HIS   B 1 48  ? 10.571  60.482  27.839  1.00 41.75 ? 47  HIS   B C    1 
ATOM   5383  O  O    . HIS   B 1 48  ? 11.100  60.270  28.935  1.00 41.02 ? 47  HIS   B O    1 
ATOM   5384  C  CB   . HIS   B 1 48  ? 10.539  58.672  26.094  1.00 42.99 ? 47  HIS   B CB   1 
ATOM   5385  C  CG   . HIS   B 1 48  ? 9.057   58.787  25.884  1.00 55.18 ? 47  HIS   B CG   1 
ATOM   5386  N  ND1  . HIS   B 1 48  ? 8.131   58.430  26.841  1.00 56.64 ? 47  HIS   B ND1  1 
ATOM   5387  C  CD2  . HIS   B 1 48  ? 8.341   59.228  24.819  1.00 59.55 ? 47  HIS   B CD2  1 
ATOM   5388  C  CE1  . HIS   B 1 48  ? 6.912   58.658  26.383  1.00 54.63 ? 47  HIS   B CE1  1 
ATOM   5389  N  NE2  . HIS   B 1 48  ? 7.012   59.139  25.157  1.00 62.29 ? 47  HIS   B NE2  1 
ATOM   5390  H  H    . HIS   B 1 48  ? 12.832  59.151  27.271  1.00 48.68 ? 47  HIS   B H    1 
ATOM   5391  H  HA   . HIS   B 1 48  ? 11.056  60.639  25.850  1.00 49.84 ? 47  HIS   B HA   1 
ATOM   5392  H  HB2  . HIS   B 1 48  ? 10.936  58.394  25.253  1.00 51.59 ? 47  HIS   B HB2  1 
ATOM   5393  H  HB3  . HIS   B 1 48  ? 10.690  57.994  26.771  1.00 51.59 ? 47  HIS   B HB3  1 
ATOM   5394  H  HD1  . HIS   B 1 48  ? 8.318   58.109  27.617  1.00 67.97 ? 47  HIS   B HD1  1 
ATOM   5395  H  HD2  . HIS   B 1 48  ? 8.686   59.535  24.012  1.00 71.46 ? 47  HIS   B HD2  1 
ATOM   5396  H  HE1  . HIS   B 1 48  ? 6.120   58.505  26.845  1.00 65.55 ? 47  HIS   B HE1  1 
ATOM   5397  N  N    . ASN   B 1 49  ? 9.417   61.151  27.710  1.00 39.19 ? 48  ASN   B N    1 
ATOM   5398  C  CA   . ASN   B 1 49  ? 8.736   61.666  28.892  1.00 43.11 ? 48  ASN   B CA   1 
ATOM   5399  C  C    . ASN   B 1 49  ? 8.468   60.563  29.908  1.00 38.82 ? 48  ASN   B C    1 
ATOM   5400  O  O    . ASN   B 1 49  ? 8.578   60.784  31.115  1.00 32.97 ? 48  ASN   B O    1 
ATOM   5401  C  CB   . ASN   B 1 49  ? 7.409   62.328  28.516  1.00 49.97 ? 48  ASN   B CB   1 
ATOM   5402  C  CG   . ASN   B 1 49  ? 7.600   63.682  27.878  1.00 56.70 ? 48  ASN   B CG   1 
ATOM   5403  O  OD1  . ASN   B 1 49  ? 8.505   64.435  28.247  1.00 55.50 ? 48  ASN   B OD1  1 
ATOM   5404  N  ND2  . ASN   B 1 49  ? 6.729   64.015  26.936  1.00 59.98 ? 48  ASN   B ND2  1 
ATOM   5405  H  H    . ASN   B 1 49  ? 9.021   61.315  26.964  1.00 47.03 ? 48  ASN   B H    1 
ATOM   5406  H  HA   . ASN   B 1 49  ? 9.312   62.336  29.291  1.00 51.73 ? 48  ASN   B HA   1 
ATOM   5407  H  HB2  . ASN   B 1 49  ? 6.939   61.762  27.884  1.00 59.97 ? 48  ASN   B HB2  1 
ATOM   5408  H  HB3  . ASN   B 1 49  ? 6.875   62.446  29.317  1.00 59.97 ? 48  ASN   B HB3  1 
ATOM   5409  H  HD21 . ASN   B 1 49  ? 6.100   63.471  26.721  1.00 71.98 ? 48  ASN   B HD21 1 
ATOM   5410  H  HD22 . ASN   B 1 49  ? 6.794   64.776  26.541  1.00 71.98 ? 48  ASN   B HD22 1 
ATOM   5411  N  N    . SER   B 1 50  ? 8.111   59.370  29.433  1.00 38.16 ? 49  SER   B N    1 
ATOM   5412  C  CA   . SER   B 1 50  ? 7.748   58.266  30.314  1.00 42.07 ? 49  SER   B CA   1 
ATOM   5413  C  C    . SER   B 1 50  ? 8.941   57.695  31.064  1.00 36.74 ? 49  SER   B C    1 
ATOM   5414  O  O    . SER   B 1 50  ? 8.744   56.865  31.955  1.00 35.85 ? 49  SER   B O    1 
ATOM   5415  C  CB   . SER   B 1 50  ? 7.067   57.161  29.501  1.00 34.89 ? 49  SER   B CB   1 
ATOM   5416  O  OG   . SER   B 1 50  ? 8.007   56.492  28.678  1.00 38.76 ? 49  SER   B OG   1 
ATOM   5417  H  HA   . SER   B 1 50  ? 7.114   58.587  30.974  1.00 50.49 ? 49  SER   B HA   1 
ATOM   5418  H  HB2  . SER   B 1 50  ? 6.668   56.520  30.110  1.00 41.86 ? 49  SER   B HB2  1 
ATOM   5419  H  HB3  . SER   B 1 50  ? 6.381   57.557  28.941  1.00 41.86 ? 49  SER   B HB3  1 
ATOM   5420  N  N    . HIS   B 1 51  ? 10.165  58.088  30.712  1.00 33.15 ? 50  HIS   B N    1 
ATOM   5421  C  CA   . HIS   B 1 51  ? 11.336  57.606  31.428  1.00 34.50 ? 50  HIS   B CA   1 
ATOM   5422  C  C    . HIS   B 1 51  ? 11.571  58.333  32.733  1.00 35.81 ? 50  HIS   B C    1 
ATOM   5423  O  O    . HIS   B 1 51  ? 12.485  57.956  33.476  1.00 33.16 ? 50  HIS   B O    1 
ATOM   5424  C  CB   . HIS   B 1 51  ? 12.589  57.757  30.582  1.00 31.55 ? 50  HIS   B CB   1 
ATOM   5425  C  CG   . HIS   B 1 51  ? 12.586  56.922  29.354  1.00 33.71 ? 50  HIS   B CG   1 
ATOM   5426  N  ND1  . HIS   B 1 51  ? 13.503  57.100  28.344  1.00 35.81 ? 50  HIS   B ND1  1 
ATOM   5427  C  CD2  . HIS   B 1 51  ? 11.794  55.893  28.975  1.00 36.43 ? 50  HIS   B CD2  1 
ATOM   5428  C  CE1  . HIS   B 1 51  ? 13.264  56.223  27.384  1.00 39.51 ? 50  HIS   B CE1  1 
ATOM   5429  N  NE2  . HIS   B 1 51  ? 12.231  55.482  27.742  1.00 36.81 ? 50  HIS   B NE2  1 
ATOM   5430  H  H    . HIS   B 1 51  ? 10.339  58.630  30.067  1.00 39.78 ? 50  HIS   B H    1 
ATOM   5431  H  HA   . HIS   B 1 51  ? 11.198  56.663  31.609  1.00 41.40 ? 50  HIS   B HA   1 
ATOM   5432  H  HB2  . HIS   B 1 51  ? 12.671  58.684  30.309  1.00 37.87 ? 50  HIS   B HB2  1 
ATOM   5433  H  HB3  . HIS   B 1 51  ? 13.358  57.498  31.113  1.00 37.87 ? 50  HIS   B HB3  1 
ATOM   5434  H  HD2  . HIS   B 1 51  ? 11.087  55.533  29.460  1.00 43.72 ? 50  HIS   B HD2  1 
ATOM   5435  H  HE1  . HIS   B 1 51  ? 13.742  56.142  26.591  1.00 47.41 ? 50  HIS   B HE1  1 
ATOM   5436  H  HE2  . HIS   B 1 51  ? 11.889  54.845  27.277  1.00 44.17 ? 50  HIS   B HE2  1 
ATOM   5437  N  N    . GLU   B 1 52  ? 10.803  59.380  33.010  1.00 34.12 ? 51  GLU   B N    1 
ATOM   5438  C  CA   . GLU   B 1 52  ? 11.046  60.170  34.201  1.00 31.45 ? 51  GLU   B CA   1 
ATOM   5439  C  C    . GLU   B 1 52  ? 10.892  59.280  35.425  1.00 29.68 ? 51  GLU   B C    1 
ATOM   5440  O  O    . GLU   B 1 52  ? 9.917   58.534  35.537  1.00 30.39 ? 51  GLU   B O    1 
ATOM   5441  C  CB   . GLU   B 1 52  ? 10.077  61.341  34.265  1.00 37.31 ? 51  GLU   B CB   1 
ATOM   5442  C  CG   . GLU   B 1 52  ? 9.730   61.722  35.653  1.00 40.98 ? 51  GLU   B CG   1 
ATOM   5443  C  CD   . GLU   B 1 52  ? 10.692  62.730  36.213  1.00 48.14 ? 51  GLU   B CD   1 
ATOM   5444  O  OE1  . GLU   B 1 52  ? 10.848  62.778  37.458  1.00 53.69 ? 51  GLU   B OE1  1 
ATOM   5445  O  OE2  . GLU   B 1 52  ? 11.265  63.502  35.400  1.00 55.17 ? 51  GLU   B OE2  1 
ATOM   5446  N  N    . GLY   B 1 53  ? 11.891  59.311  36.301  1.00 26.63 ? 52  GLY   B N    1 
ATOM   5447  C  CA   . GLY   B 1 53  ? 11.842  58.554  37.537  1.00 29.27 ? 52  GLY   B CA   1 
ATOM   5448  C  C    . GLY   B 1 53  ? 12.287  57.108  37.424  1.00 27.85 ? 52  GLY   B C    1 
ATOM   5449  O  O    . GLY   B 1 53  ? 12.368  56.422  38.457  1.00 26.47 ? 52  GLY   B O    1 
ATOM   5450  H  H    . GLY   B 1 53  ? 12.612  59.769  36.198  1.00 31.95 ? 52  GLY   B H    1 
ATOM   5451  H  HA2  . GLY   B 1 53  ? 12.414  58.988  38.189  1.00 35.12 ? 52  GLY   B HA2  1 
ATOM   5452  H  HA3  . GLY   B 1 53  ? 10.930  58.556  37.865  1.00 35.12 ? 52  GLY   B HA3  1 
ATOM   5453  N  N    . LYS   B 1 54  ? 12.583  56.625  36.224  1.00 28.47 ? 53  LYS   B N    1 
ATOM   5454  C  CA   . LYS   B 1 54  ? 12.955  55.230  36.036  1.00 24.30 ? 53  LYS   B CA   1 
ATOM   5455  C  C    . LYS   B 1 54  ? 14.446  55.030  36.305  1.00 24.71 ? 53  LYS   B C    1 
ATOM   5456  O  O    . LYS   B 1 54  ? 15.230  55.983  36.362  1.00 22.76 ? 53  LYS   B O    1 
ATOM   5457  C  CB   . LYS   B 1 54  ? 12.604  54.775  34.632  1.00 27.92 ? 53  LYS   B CB   1 
ATOM   5458  C  CG   . LYS   B 1 54  ? 11.111  54.759  34.334  1.00 29.03 ? 53  LYS   B CG   1 
ATOM   5459  C  CD   . LYS   B 1 54  ? 10.847  54.056  33.003  1.00 37.45 ? 53  LYS   B CD   1 
ATOM   5460  C  CE   . LYS   B 1 54  ? 9.680   53.105  33.066  1.00 44.97 ? 53  LYS   B CE   1 
ATOM   5461  N  NZ   . LYS   B 1 54  ? 8.447   53.894  33.244  1.00 49.11 ? 53  LYS   B NZ   1 
ATOM   5462  H  H    . LYS   B 1 54  ? 12.576  57.087  35.499  1.00 34.17 ? 53  LYS   B H    1 
ATOM   5463  H  HA   . LYS   B 1 54  ? 12.464  54.676  36.663  1.00 29.16 ? 53  LYS   B HA   1 
ATOM   5464  H  HB2  . LYS   B 1 54  ? 13.024  55.376  33.997  1.00 33.50 ? 53  LYS   B HB2  1 
ATOM   5465  H  HB3  . LYS   B 1 54  ? 12.938  53.873  34.507  1.00 33.50 ? 53  LYS   B HB3  1 
ATOM   5466  H  HG2  . LYS   B 1 54  ? 10.643  54.280  35.036  1.00 34.84 ? 53  LYS   B HG2  1 
ATOM   5467  H  HG3  . LYS   B 1 54  ? 10.780  55.669  34.275  1.00 34.84 ? 53  LYS   B HG3  1 
ATOM   5468  H  HD2  . LYS   B 1 54  ? 10.653  54.722  32.326  1.00 44.94 ? 53  LYS   B HD2  1 
ATOM   5469  H  HD3  . LYS   B 1 54  ? 11.634  53.547  32.752  1.00 44.94 ? 53  LYS   B HD3  1 
ATOM   5470  H  HE2  . LYS   B 1 54  ? 9.617   52.599  32.241  1.00 53.97 ? 53  LYS   B HE2  1 
ATOM   5471  H  HE3  . LYS   B 1 54  ? 9.783   52.502  33.819  1.00 53.97 ? 53  LYS   B HE3  1 
ATOM   5472  H  HZ1  . LYS   B 1 54  ? 7.750   53.446  32.922  1.00 58.94 ? 53  LYS   B HZ1  1 
ATOM   5473  H  HZ2  . LYS   B 1 54  ? 8.312   54.057  34.109  1.00 58.94 ? 53  LYS   B HZ2  1 
ATOM   5474  H  HZ3  . LYS   B 1 54  ? 8.517   54.669  32.812  1.00 58.94 ? 53  LYS   B HZ3  1 
ATOM   5475  N  N    . THR   B 1 55  ? 14.826  53.761  36.501  1.00 22.83 ? 54  THR   B N    1 
ATOM   5476  C  CA   . THR   B 1 55  ? 16.195  53.382  36.819  1.00 22.50 ? 54  THR   B CA   1 
ATOM   5477  C  C    . THR   B 1 55  ? 16.833  52.764  35.579  1.00 27.95 ? 54  THR   B C    1 
ATOM   5478  O  O    . THR   B 1 55  ? 16.223  51.903  34.934  1.00 27.93 ? 54  THR   B O    1 
ATOM   5479  C  CB   . THR   B 1 55  ? 16.222  52.405  37.996  1.00 23.74 ? 54  THR   B CB   1 
ATOM   5480  O  OG1  . THR   B 1 55  ? 15.715  53.063  39.177  1.00 27.47 ? 54  THR   B OG1  1 
ATOM   5481  C  CG2  . THR   B 1 55  ? 17.649  51.922  38.230  1.00 24.51 ? 54  THR   B CG2  1 
ATOM   5482  H  H    . THR   B 1 55  ? 14.290  53.091  36.452  1.00 27.39 ? 54  THR   B H    1 
ATOM   5483  H  HA   . THR   B 1 55  ? 16.715  54.162  37.068  1.00 27.01 ? 54  THR   B HA   1 
ATOM   5484  H  HB   . THR   B 1 55  ? 15.667  51.632  37.809  1.00 28.49 ? 54  THR   B HB   1 
ATOM   5485  H  HG1  . THR   B 1 55  ? 16.337  53.469  39.569  1.00 32.96 ? 54  THR   B HG1  1 
ATOM   5486  H  HG21 . THR   B 1 55  ? 17.748  51.609  39.143  1.00 29.41 ? 54  THR   B HG21 1 
ATOM   5487  H  HG22 . THR   B 1 55  ? 17.857  51.193  37.624  1.00 29.41 ? 54  THR   B HG22 1 
ATOM   5488  H  HG23 . THR   B 1 55  ? 18.274  52.647  38.077  1.00 29.41 ? 54  THR   B HG23 1 
ATOM   5489  N  N    . PHE   B 1 56  ? 18.045  53.221  35.246  1.00 26.14 ? 55  PHE   B N    1 
ATOM   5490  C  CA   . PHE   B 1 56  ? 18.798  52.782  34.074  1.00 25.51 ? 55  PHE   B CA   1 
ATOM   5491  C  C    . PHE   B 1 56  ? 20.106  52.167  34.543  1.00 27.70 ? 55  PHE   B C    1 
ATOM   5492  O  O    . PHE   B 1 56  ? 20.760  52.713  35.432  1.00 26.92 ? 55  PHE   B O    1 
ATOM   5493  C  CB   . PHE   B 1 56  ? 19.128  53.966  33.129  1.00 25.14 ? 55  PHE   B CB   1 
ATOM   5494  C  CG   . PHE   B 1 56  ? 17.928  54.541  32.473  1.00 28.34 ? 55  PHE   B CG   1 
ATOM   5495  C  CD1  . PHE   B 1 56  ? 17.078  55.375  33.168  1.00 24.19 ? 55  PHE   B CD1  1 
ATOM   5496  C  CD2  . PHE   B 1 56  ? 17.622  54.223  31.172  1.00 29.21 ? 55  PHE   B CD2  1 
ATOM   5497  C  CE1  . PHE   B 1 56  ? 15.938  55.899  32.566  1.00 25.86 ? 55  PHE   B CE1  1 
ATOM   5498  C  CE2  . PHE   B 1 56  ? 16.485  54.748  30.563  1.00 30.26 ? 55  PHE   B CE2  1 
ATOM   5499  C  CZ   . PHE   B 1 56  ? 15.644  55.569  31.255  1.00 30.98 ? 55  PHE   B CZ   1 
ATOM   5500  H  H    . PHE   B 1 56  ? 18.467  53.812  35.707  1.00 31.37 ? 55  PHE   B H    1 
ATOM   5501  H  HA   . PHE   B 1 56  ? 18.276  52.129  33.582  1.00 30.61 ? 55  PHE   B HA   1 
ATOM   5502  H  HB2  . PHE   B 1 56  ? 19.553  54.670  33.644  1.00 30.17 ? 55  PHE   B HB2  1 
ATOM   5503  H  HB3  . PHE   B 1 56  ? 19.728  53.655  32.433  1.00 30.17 ? 55  PHE   B HB3  1 
ATOM   5504  H  HD1  . PHE   B 1 56  ? 17.269  55.590  34.053  1.00 29.03 ? 55  PHE   B HD1  1 
ATOM   5505  H  HD2  . PHE   B 1 56  ? 18.179  53.652  30.694  1.00 35.05 ? 55  PHE   B HD2  1 
ATOM   5506  H  HE1  . PHE   B 1 56  ? 15.377  56.467  33.042  1.00 31.03 ? 55  PHE   B HE1  1 
ATOM   5507  H  HE2  . PHE   B 1 56  ? 16.297  54.536  29.677  1.00 36.31 ? 55  PHE   B HE2  1 
ATOM   5508  H  HZ   . PHE   B 1 56  ? 14.879  55.906  30.849  1.00 37.18 ? 55  PHE   B HZ   1 
ATOM   5509  N  N    . TYR   B 1 57  ? 20.502  51.053  33.942  1.00 24.38 ? 56  TYR   B N    1 
ATOM   5510  C  CA   . TYR   B 1 57  ? 21.841  50.534  34.167  1.00 25.23 ? 56  TYR   B CA   1 
ATOM   5511  C  C    . TYR   B 1 57  ? 22.842  51.219  33.246  1.00 32.04 ? 56  TYR   B C    1 
ATOM   5512  O  O    . TYR   B 1 57  ? 22.566  51.440  32.061  1.00 30.39 ? 56  TYR   B O    1 
ATOM   5513  C  CB   . TYR   B 1 57  ? 21.890  49.014  33.940  1.00 29.19 ? 56  TYR   B CB   1 
ATOM   5514  C  CG   . TYR   B 1 57  ? 21.353  48.160  35.066  1.00 25.23 ? 56  TYR   B CG   1 
ATOM   5515  C  CD1  . TYR   B 1 57  ? 19.985  48.071  35.312  1.00 30.27 ? 56  TYR   B CD1  1 
ATOM   5516  C  CD2  . TYR   B 1 57  ? 22.207  47.412  35.862  1.00 28.76 ? 56  TYR   B CD2  1 
ATOM   5517  C  CE1  . TYR   B 1 57  ? 19.489  47.269  36.332  1.00 30.04 ? 56  TYR   B CE1  1 
ATOM   5518  C  CE2  . TYR   B 1 57  ? 21.721  46.626  36.888  1.00 25.59 ? 56  TYR   B CE2  1 
ATOM   5519  C  CZ   . TYR   B 1 57  ? 20.363  46.546  37.110  1.00 29.79 ? 56  TYR   B CZ   1 
ATOM   5520  O  OH   . TYR   B 1 57  ? 19.858  45.753  38.122  1.00 32.12 ? 56  TYR   B OH   1 
ATOM   5521  H  H    . TYR   B 1 57  ? 20.019  50.585  33.406  1.00 29.25 ? 56  TYR   B H    1 
ATOM   5522  H  HA   . TYR   B 1 57  ? 22.092  50.709  35.087  1.00 30.28 ? 56  TYR   B HA   1 
ATOM   5523  H  HB2  . TYR   B 1 57  ? 21.368  48.807  33.149  1.00 35.03 ? 56  TYR   B HB2  1 
ATOM   5524  H  HB3  . TYR   B 1 57  ? 22.816  48.757  33.803  1.00 35.03 ? 56  TYR   B HB3  1 
ATOM   5525  H  HD1  . TYR   B 1 57  ? 19.394  48.556  34.783  1.00 36.33 ? 56  TYR   B HD1  1 
ATOM   5526  H  HD2  . TYR   B 1 57  ? 23.122  47.440  35.702  1.00 34.52 ? 56  TYR   B HD2  1 
ATOM   5527  H  HE1  . TYR   B 1 57  ? 18.573  47.222  36.488  1.00 36.04 ? 56  TYR   B HE1  1 
ATOM   5528  H  HE2  . TYR   B 1 57  ? 22.310  46.151  37.429  1.00 30.71 ? 56  TYR   B HE2  1 
ATOM   5529  H  HH   . TYR   B 1 57  ? 19.059  45.961  38.278  1.00 38.54 ? 56  TYR   B HH   1 
ATOM   5530  N  N    . VAL   B 1 58  ? 24.016  51.544  33.798  1.00 28.99 ? 57  VAL   B N    1 
ATOM   5531  C  CA   . VAL   B 1 58  ? 25.113  52.137  33.044  1.00 30.34 ? 57  VAL   B CA   1 
ATOM   5532  C  C    . VAL   B 1 58  ? 26.383  51.351  33.334  1.00 33.47 ? 57  VAL   B C    1 
ATOM   5533  O  O    . VAL   B 1 58  ? 26.513  50.694  34.369  1.00 34.37 ? 57  VAL   B O    1 
ATOM   5534  C  CB   . VAL   B 1 58  ? 25.321  53.633  33.374  1.00 27.80 ? 57  VAL   B CB   1 
ATOM   5535  C  CG1  . VAL   B 1 58  ? 24.090  54.441  32.947  1.00 32.64 ? 57  VAL   B CG1  1 
ATOM   5536  C  CG2  . VAL   B 1 58  ? 25.633  53.805  34.862  1.00 33.50 ? 57  VAL   B CG2  1 
ATOM   5537  H  H    . VAL   B 1 58  ? 24.200  51.425  34.630  1.00 34.79 ? 57  VAL   B H    1 
ATOM   5538  H  HA   . VAL   B 1 58  ? 24.918  52.065  32.096  1.00 36.41 ? 57  VAL   B HA   1 
ATOM   5539  H  HB   . VAL   B 1 58  ? 26.080  53.979  32.879  1.00 33.36 ? 57  VAL   B HB   1 
ATOM   5540  H  HG11 . VAL   B 1 58  ? 24.343  55.371  32.845  1.00 39.17 ? 57  VAL   B HG11 1 
ATOM   5541  H  HG12 . VAL   B 1 58  ? 23.762  54.093  32.103  1.00 39.17 ? 57  VAL   B HG12 1 
ATOM   5542  H  HG13 . VAL   B 1 58  ? 23.405  54.357  33.628  1.00 39.17 ? 57  VAL   B HG13 1 
ATOM   5543  H  HG21 . VAL   B 1 58  ? 25.560  54.744  35.094  1.00 40.21 ? 57  VAL   B HG21 1 
ATOM   5544  H  HG22 . VAL   B 1 58  ? 24.998  53.286  35.380  1.00 40.21 ? 57  VAL   B HG22 1 
ATOM   5545  H  HG23 . VAL   B 1 58  ? 26.535  53.492  35.034  1.00 40.21 ? 57  VAL   B HG23 1 
ATOM   5546  N  N    . LEU   B 1 59  ? 27.333  51.429  32.405  1.00 32.84 ? 58  LEU   B N    1 
ATOM   5547  C  CA   . LEU   B 1 59  ? 28.618  50.784  32.619  1.00 38.11 ? 58  LEU   B CA   1 
ATOM   5548  C  C    . LEU   B 1 59  ? 29.405  51.555  33.670  1.00 41.97 ? 58  LEU   B C    1 
ATOM   5549  O  O    . LEU   B 1 59  ? 29.348  52.787  33.715  1.00 48.32 ? 58  LEU   B O    1 
ATOM   5550  C  CB   . LEU   B 1 59  ? 29.447  50.723  31.334  1.00 43.04 ? 58  LEU   B CB   1 
ATOM   5551  C  CG   . LEU   B 1 59  ? 29.595  49.406  30.577  1.00 53.46 ? 58  LEU   B CG   1 
ATOM   5552  C  CD1  . LEU   B 1 59  ? 30.090  49.667  29.163  1.00 51.44 ? 58  LEU   B CD1  1 
ATOM   5553  C  CD2  . LEU   B 1 59  ? 30.562  48.469  31.296  1.00 53.46 ? 58  LEU   B CD2  1 
ATOM   5554  H  H    . LEU   B 1 59  ? 27.256  51.844  31.655  1.00 39.41 ? 58  LEU   B H    1 
ATOM   5555  H  HA   . LEU   B 1 59  ? 28.465  49.874  32.917  1.00 45.73 ? 58  LEU   B HA   1 
ATOM   5556  H  HB2  . LEU   B 1 59  ? 29.050  51.349  30.708  1.00 51.65 ? 58  LEU   B HB2  1 
ATOM   5557  H  HB3  . LEU   B 1 59  ? 30.347  51.005  31.560  1.00 51.65 ? 58  LEU   B HB3  1 
ATOM   5558  H  HG   . LEU   B 1 59  ? 28.728  48.974  30.534  1.00 64.15 ? 58  LEU   B HG   1 
ATOM   5559  H  HD11 . LEU   B 1 59  ? 30.177  48.820  28.698  1.00 61.73 ? 58  LEU   B HD11 1 
ATOM   5560  H  HD12 . LEU   B 1 59  ? 29.449  50.232  28.703  1.00 61.73 ? 58  LEU   B HD12 1 
ATOM   5561  H  HD13 . LEU   B 1 59  ? 30.951  50.110  29.206  1.00 61.73 ? 58  LEU   B HD13 1 
ATOM   5562  H  HD21 . LEU   B 1 59  ? 30.635  47.643  30.792  1.00 64.15 ? 58  LEU   B HD21 1 
ATOM   5563  H  HD22 . LEU   B 1 59  ? 31.430  48.897  31.357  1.00 64.15 ? 58  LEU   B HD22 1 
ATOM   5564  H  HD23 . LEU   B 1 59  ? 30.221  48.284  32.185  1.00 64.15 ? 58  LEU   B HD23 1 
ATOM   5565  N  N    . PRO   B 1 60  ? 30.178  50.860  34.497  1.00 40.54 ? 59  PRO   B N    1 
ATOM   5566  C  CA   . PRO   B 1 60  ? 31.002  51.563  35.492  1.00 46.08 ? 59  PRO   B CA   1 
ATOM   5567  C  C    . PRO   B 1 60  ? 32.018  52.473  34.815  1.00 54.23 ? 59  PRO   B C    1 
ATOM   5568  O  O    . PRO   B 1 60  ? 32.960  51.979  34.191  1.00 58.89 ? 59  PRO   B O    1 
ATOM   5569  C  CB   . PRO   B 1 60  ? 31.692  50.416  36.245  1.00 44.68 ? 59  PRO   B CB   1 
ATOM   5570  C  CG   . PRO   B 1 60  ? 30.752  49.234  36.080  1.00 46.89 ? 59  PRO   B CG   1 
ATOM   5571  C  CD   . PRO   B 1 60  ? 30.221  49.394  34.672  1.00 44.62 ? 59  PRO   B CD   1 
ATOM   5572  H  HA   . PRO   B 1 60  ? 30.454  52.069  36.113  1.00 55.29 ? 59  PRO   B HA   1 
ATOM   5573  H  HB2  . PRO   B 1 60  ? 32.558  50.231  35.848  1.00 53.62 ? 59  PRO   B HB2  1 
ATOM   5574  H  HB3  . PRO   B 1 60  ? 31.799  50.649  37.180  1.00 53.62 ? 59  PRO   B HB3  1 
ATOM   5575  H  HG2  . PRO   B 1 60  ? 31.239  48.400  36.180  1.00 56.27 ? 59  PRO   B HG2  1 
ATOM   5576  H  HG3  . PRO   B 1 60  ? 30.036  49.280  36.733  1.00 56.27 ? 59  PRO   B HG3  1 
ATOM   5577  H  HD2  . PRO   B 1 60  ? 30.820  48.986  34.027  1.00 53.55 ? 59  PRO   B HD2  1 
ATOM   5578  H  HD3  . PRO   B 1 60  ? 29.334  49.009  34.590  1.00 53.55 ? 59  PRO   B HD3  1 
ATOM   5579  N  N    . ASN   B 1 61  ? 31.844  53.792  34.910  1.00 50.94 ? 60  ASN   B N    1 
ATOM   5580  C  CA   . ASN   B 1 61  ? 32.728  54.739  34.242  1.00 52.96 ? 60  ASN   B CA   1 
ATOM   5581  C  C    . ASN   B 1 61  ? 33.573  55.559  35.207  1.00 56.68 ? 60  ASN   B C    1 
ATOM   5582  O  O    . ASN   B 1 61  ? 34.361  56.397  34.754  1.00 52.47 ? 60  ASN   B O    1 
ATOM   5583  C  CB   . ASN   B 1 61  ? 31.925  55.711  33.361  1.00 54.34 ? 60  ASN   B CB   1 
ATOM   5584  C  CG   . ASN   B 1 61  ? 30.677  56.232  34.061  1.00 59.92 ? 60  ASN   B CG   1 
ATOM   5585  O  OD1  . ASN   B 1 61  ? 30.756  57.101  34.932  1.00 63.27 ? 60  ASN   B OD1  1 
ATOM   5586  N  ND2  . ASN   B 1 61  ? 29.509  55.771  33.613  1.00 57.10 ? 60  ASN   B ND2  1 
ATOM   5587  H  H    . ASN   B 1 61  ? 31.213  54.164  35.360  1.00 61.12 ? 60  ASN   B H    1 
ATOM   5588  H  HA   . ASN   B 1 61  ? 33.321  54.224  33.672  1.00 63.55 ? 60  ASN   B HA   1 
ATOM   5589  H  HB2  . ASN   B 1 61  ? 32.484  56.472  33.136  1.00 65.21 ? 60  ASN   B HB2  1 
ATOM   5590  H  HB3  . ASN   B 1 61  ? 31.648  55.253  32.553  1.00 65.21 ? 60  ASN   B HB3  1 
ATOM   5591  H  HD21 . ASN   B 1 61  ? 28.775  56.034  33.975  1.00 68.52 ? 60  ASN   B HD21 1 
ATOM   5592  H  HD22 . ASN   B 1 61  ? 29.490  55.209  32.962  1.00 68.52 ? 60  ASN   B HD22 1 
ATOM   5593  N  N    . ASP   B 1 62  ? 33.424  55.352  36.514  1.00 54.89 ? 61  ASP   B N    1 
ATOM   5594  C  CA   . ASP   B 1 62  ? 34.227  56.025  37.525  1.00 50.66 ? 61  ASP   B CA   1 
ATOM   5595  C  C    . ASP   B 1 62  ? 34.522  55.035  38.643  1.00 52.79 ? 61  ASP   B C    1 
ATOM   5596  O  O    . ASP   B 1 62  ? 33.927  53.958  38.721  1.00 48.86 ? 61  ASP   B O    1 
ATOM   5597  C  CB   . ASP   B 1 62  ? 33.514  57.269  38.068  1.00 53.22 ? 61  ASP   B CB   1 
ATOM   5598  C  CG   . ASP   B 1 62  ? 32.163  56.951  38.705  1.00 55.66 ? 61  ASP   B CG   1 
ATOM   5599  O  OD1  . ASP   B 1 62  ? 32.097  56.058  39.583  1.00 53.39 ? 61  ASP   B OD1  1 
ATOM   5600  O  OD2  . ASP   B 1 62  ? 31.164  57.605  38.330  1.00 59.71 ? 61  ASP   B OD2  1 
ATOM   5601  H  H    . ASP   B 1 62  ? 32.846  54.810  36.847  1.00 65.87 ? 61  ASP   B H    1 
ATOM   5602  H  HA   . ASP   B 1 62  ? 35.070  56.310  37.139  1.00 60.79 ? 61  ASP   B HA   1 
ATOM   5603  H  HB2  . ASP   B 1 62  ? 34.073  57.683  38.743  1.00 63.86 ? 61  ASP   B HB2  1 
ATOM   5604  H  HB3  . ASP   B 1 62  ? 33.361  57.889  37.337  1.00 63.86 ? 61  ASP   B HB3  1 
ATOM   5605  N  N    . ASP   B 1 63  ? 35.438  55.409  39.535  1.00 52.68 ? 62  ASP   B N    1 
ATOM   5606  C  CA   . ASP   B 1 63  ? 35.870  54.459  40.554  1.00 54.65 ? 62  ASP   B CA   1 
ATOM   5607  C  C    . ASP   B 1 63  ? 34.733  54.111  41.507  1.00 49.35 ? 62  ASP   B C    1 
ATOM   5608  O  O    . ASP   B 1 63  ? 34.674  52.989  42.018  1.00 45.08 ? 62  ASP   B O    1 
ATOM   5609  C  CB   . ASP   B 1 63  ? 37.070  55.008  41.325  1.00 56.09 ? 62  ASP   B CB   1 
ATOM   5610  C  CG   . ASP   B 1 63  ? 38.317  55.115  40.462  1.00 58.57 ? 62  ASP   B CG   1 
ATOM   5611  O  OD1  . ASP   B 1 63  ? 39.362  55.570  40.981  1.00 67.11 ? 62  ASP   B OD1  1 
ATOM   5612  O  OD2  . ASP   B 1 63  ? 38.255  54.759  39.266  1.00 65.95 ? 62  ASP   B OD2  1 
ATOM   5613  H  H    . ASP   B 1 63  ? 35.814  56.182  39.569  1.00 63.21 ? 62  ASP   B H    1 
ATOM   5614  H  HA   . ASP   B 1 63  ? 36.156  53.642  40.116  1.00 65.58 ? 62  ASP   B HA   1 
ATOM   5615  H  HB2  . ASP   B 1 63  ? 36.856  55.894  41.656  1.00 67.31 ? 62  ASP   B HB2  1 
ATOM   5616  H  HB3  . ASP   B 1 63  ? 37.268  54.415  42.067  1.00 67.31 ? 62  ASP   B HB3  1 
ATOM   5617  N  N    . THR   B 1 64  ? 33.836  55.056  41.777  1.00 50.84 ? 63  THR   B N    1 
ATOM   5618  C  CA   . THR   B 1 64  ? 32.683  54.749  42.616  1.00 49.40 ? 63  THR   B CA   1 
ATOM   5619  C  C    . THR   B 1 64  ? 31.823  53.655  41.987  1.00 41.65 ? 63  THR   B C    1 
ATOM   5620  O  O    . THR   B 1 64  ? 31.440  52.689  42.654  1.00 37.65 ? 63  THR   B O    1 
ATOM   5621  C  CB   . THR   B 1 64  ? 31.859  56.016  42.854  1.00 52.58 ? 63  THR   B CB   1 
ATOM   5622  O  OG1  . THR   B 1 64  ? 32.608  56.930  43.665  1.00 58.92 ? 63  THR   B OG1  1 
ATOM   5623  C  CG2  . THR   B 1 64  ? 30.553  55.688  43.544  1.00 47.89 ? 63  THR   B CG2  1 
ATOM   5624  H  H    . THR   B 1 64  ? 33.872  55.867  41.494  1.00 61.00 ? 63  THR   B H    1 
ATOM   5625  H  HA   . THR   B 1 64  ? 32.996  54.427  43.476  1.00 59.27 ? 63  THR   B HA   1 
ATOM   5626  H  HB   . THR   B 1 64  ? 31.655  56.430  42.001  1.00 63.10 ? 63  THR   B HB   1 
ATOM   5627  H  HG1  . THR   B 1 64  ? 32.164  57.631  43.793  1.00 70.70 ? 63  THR   B HG1  1 
ATOM   5628  H  HG21 . THR   B 1 64  ? 30.186  56.485  43.956  1.00 57.47 ? 63  THR   B HG21 1 
ATOM   5629  H  HG22 . THR   B 1 64  ? 29.915  55.344  42.900  1.00 57.47 ? 63  THR   B HG22 1 
ATOM   5630  H  HG23 . THR   B 1 64  ? 30.700  55.018  44.230  1.00 57.47 ? 63  THR   B HG23 1 
ATOM   5631  N  N    . LEU   B 1 65  ? 31.503  53.789  40.702  1.00 42.39 ? 64  LEU   B N    1 
ATOM   5632  C  CA   . LEU   B 1 65  ? 30.685  52.772  40.050  1.00 44.66 ? 64  LEU   B CA   1 
ATOM   5633  C  C    . LEU   B 1 65  ? 31.426  51.444  39.936  1.00 38.53 ? 64  LEU   B C    1 
ATOM   5634  O  O    . LEU   B 1 65  ? 30.803  50.382  39.975  1.00 34.73 ? 64  LEU   B O    1 
ATOM   5635  C  CB   . LEU   B 1 65  ? 30.262  53.262  38.672  1.00 46.03 ? 64  LEU   B CB   1 
ATOM   5636  C  CG   . LEU   B 1 65  ? 29.185  54.344  38.661  1.00 43.35 ? 64  LEU   B CG   1 
ATOM   5637  C  CD1  . LEU   B 1 65  ? 28.773  54.607  37.228  1.00 44.45 ? 64  LEU   B CD1  1 
ATOM   5638  C  CD2  . LEU   B 1 65  ? 27.946  53.976  39.479  1.00 43.40 ? 64  LEU   B CD2  1 
ATOM   5639  H  H    . LEU   B 1 65  ? 31.741  54.444  40.197  1.00 50.87 ? 64  LEU   B H    1 
ATOM   5640  H  HA   . LEU   B 1 65  ? 29.886  52.621  40.579  1.00 53.60 ? 64  LEU   B HA   1 
ATOM   5641  H  HB2  . LEU   B 1 65  ? 31.042  53.627  38.226  1.00 55.24 ? 64  LEU   B HB2  1 
ATOM   5642  H  HB3  . LEU   B 1 65  ? 29.917  52.506  38.172  1.00 55.24 ? 64  LEU   B HB3  1 
ATOM   5643  H  HG   . LEU   B 1 65  ? 29.559  55.139  39.071  1.00 52.02 ? 64  LEU   B HG   1 
ATOM   5644  H  HD11 . LEU   B 1 65  ? 28.437  55.514  37.157  1.00 53.34 ? 64  LEU   B HD11 1 
ATOM   5645  H  HD12 . LEU   B 1 65  ? 29.545  54.494  36.651  1.00 53.34 ? 64  LEU   B HD12 1 
ATOM   5646  H  HD13 . LEU   B 1 65  ? 28.079  53.977  36.978  1.00 53.34 ? 64  LEU   B HD13 1 
ATOM   5647  H  HD21 . LEU   B 1 65  ? 27.182  54.461  39.130  1.00 52.08 ? 64  LEU   B HD21 1 
ATOM   5648  H  HD22 . LEU   B 1 65  ? 27.792  53.021  39.407  1.00 52.08 ? 64  LEU   B HD22 1 
ATOM   5649  H  HD23 . LEU   B 1 65  ? 28.097  54.217  40.406  1.00 52.08 ? 64  LEU   B HD23 1 
ATOM   5650  N  N    . ARG   B 1 66  ? 32.739  51.492  39.734  1.00 40.53 ? 65  ARG   B N    1 
ATOM   5651  C  CA   . ARG   B 1 66  ? 33.524  50.272  39.596  1.00 41.52 ? 65  ARG   B CA   1 
ATOM   5652  C  C    . ARG   B 1 66  ? 33.561  49.502  40.904  1.00 40.31 ? 65  ARG   B C    1 
ATOM   5653  O  O    . ARG   B 1 66  ? 33.513  48.265  40.914  1.00 32.69 ? 65  ARG   B O    1 
ATOM   5654  C  CB   . ARG   B 1 66  ? 34.925  50.635  39.123  1.00 40.74 ? 65  ARG   B CB   1 
ATOM   5655  C  CG   . ARG   B 1 66  ? 34.986  50.723  37.604  1.00 42.48 ? 65  ARG   B CG   1 
ATOM   5656  C  CD   . ARG   B 1 66  ? 36.382  51.007  37.126  1.00 54.66 ? 65  ARG   B CD   1 
ATOM   5657  N  NE   . ARG   B 1 66  ? 36.719  52.413  37.292  1.00 58.48 ? 65  ARG   B NE   1 
ATOM   5658  C  CZ   . ARG   B 1 66  ? 37.002  53.235  36.293  1.00 53.56 ? 65  ARG   B CZ   1 
ATOM   5659  N  NH1  . ARG   B 1 66  ? 36.748  52.908  35.035  1.00 63.27 ? 65  ARG   B NH1  1 
ATOM   5660  N  NH2  . ARG   B 1 66  ? 37.528  54.425  36.561  1.00 61.72 ? 65  ARG   B NH2  1 
ATOM   5661  H  H    . ARG   B 1 66  ? 33.199  52.216  39.674  1.00 48.64 ? 65  ARG   B H    1 
ATOM   5662  H  HA   . ARG   B 1 66  ? 33.123  49.691  38.930  1.00 49.82 ? 65  ARG   B HA   1 
ATOM   5663  H  HB2  . ARG   B 1 66  ? 35.176  51.496  39.491  1.00 48.89 ? 65  ARG   B HB2  1 
ATOM   5664  H  HB3  . ARG   B 1 66  ? 35.550  49.954  39.417  1.00 48.89 ? 65  ARG   B HB3  1 
ATOM   5665  H  HG2  . ARG   B 1 66  ? 34.699  49.879  37.222  1.00 50.98 ? 65  ARG   B HG2  1 
ATOM   5666  H  HG3  . ARG   B 1 66  ? 34.407  51.439  37.300  1.00 50.98 ? 65  ARG   B HG3  1 
ATOM   5667  H  HD2  . ARG   B 1 66  ? 37.012  50.479  37.640  1.00 65.59 ? 65  ARG   B HD2  1 
ATOM   5668  H  HD3  . ARG   B 1 66  ? 36.452  50.784  36.185  1.00 65.59 ? 65  ARG   B HD3  1 
ATOM   5669  H  HE   . ARG   B 1 66  ? 36.736  52.731  38.091  1.00 70.18 ? 65  ARG   B HE   1 
ATOM   5670  H  HH11 . ARG   B 1 66  ? 36.393  52.147  34.852  1.00 75.92 ? 65  ARG   B HH11 1 
ATOM   5671  H  HH12 . ARG   B 1 66  ? 36.940  53.457  34.401  1.00 75.92 ? 65  ARG   B HH12 1 
ATOM   5672  H  HH21 . ARG   B 1 66  ? 37.682  54.654  37.376  1.00 74.06 ? 65  ARG   B HH21 1 
ATOM   5673  H  HH22 . ARG   B 1 66  ? 37.716  54.967  35.921  1.00 74.06 ? 65  ARG   B HH22 1 
ATOM   5674  N  N    . VAL   B 1 67  ? 33.648  50.221  42.021  1.00 37.75 ? 66  VAL   B N    1 
ATOM   5675  C  CA   . VAL   B 1 67  ? 33.602  49.566  43.317  1.00 35.55 ? 66  VAL   B CA   1 
ATOM   5676  C  C    . VAL   B 1 67  ? 32.225  48.971  43.556  1.00 33.45 ? 66  VAL   B C    1 
ATOM   5677  O  O    . VAL   B 1 67  ? 32.100  47.826  43.999  1.00 34.72 ? 66  VAL   B O    1 
ATOM   5678  C  CB   . VAL   B 1 67  ? 33.978  50.549  44.439  1.00 41.28 ? 66  VAL   B CB   1 
ATOM   5679  C  CG1  . VAL   B 1 67  ? 33.612  49.946  45.802  1.00 39.24 ? 66  VAL   B CG1  1 
ATOM   5680  C  CG2  . VAL   B 1 67  ? 35.451  50.883  44.378  1.00 42.20 ? 66  VAL   B CG2  1 
ATOM   5681  H  H    . VAL   B 1 67  ? 33.734  51.076  42.052  1.00 45.30 ? 66  VAL   B H    1 
ATOM   5682  H  HA   . VAL   B 1 67  ? 34.254  48.848  43.316  1.00 42.66 ? 66  VAL   B HA   1 
ATOM   5683  H  HB   . VAL   B 1 67  ? 33.481  51.374  44.325  1.00 49.54 ? 66  VAL   B HB   1 
ATOM   5684  H  HG11 . VAL   B 1 67  ? 34.130  50.389  46.493  1.00 47.09 ? 66  VAL   B HG11 1 
ATOM   5685  H  HG12 . VAL   B 1 67  ? 32.664  50.080  45.962  1.00 47.09 ? 66  VAL   B HG12 1 
ATOM   5686  H  HG13 . VAL   B 1 67  ? 33.815  48.998  45.793  1.00 47.09 ? 66  VAL   B HG13 1 
ATOM   5687  H  HG21 . VAL   B 1 67  ? 35.566  51.834  44.530  1.00 50.64 ? 66  VAL   B HG21 1 
ATOM   5688  H  HG22 . VAL   B 1 67  ? 35.918  50.380  45.064  1.00 50.64 ? 66  VAL   B HG22 1 
ATOM   5689  H  HG23 . VAL   B 1 67  ? 35.793  50.644  43.502  1.00 50.64 ? 66  VAL   B HG23 1 
ATOM   5690  N  N    . GLU   B 1 68  ? 31.167  49.739  43.278  1.00 34.12 ? 67  GLU   B N    1 
ATOM   5691  C  CA   . GLU   B 1 68  ? 29.831  49.203  43.486  1.00 31.81 ? 67  GLU   B CA   1 
ATOM   5692  C  C    . GLU   B 1 68  ? 29.617  47.959  42.623  1.00 26.87 ? 67  GLU   B C    1 
ATOM   5693  O  O    . GLU   B 1 68  ? 29.057  46.968  43.089  1.00 29.02 ? 67  GLU   B O    1 
ATOM   5694  C  CB   . GLU   B 1 68  ? 28.756  50.255  43.186  1.00 30.77 ? 67  GLU   B CB   1 
ATOM   5695  C  CG   . GLU   B 1 68  ? 28.844  51.494  44.086  1.00 33.81 ? 67  GLU   B CG   1 
ATOM   5696  C  CD   . GLU   B 1 68  ? 27.728  52.531  43.850  1.00 38.19 ? 67  GLU   B CD   1 
ATOM   5697  O  OE1  . GLU   B 1 68  ? 27.211  52.648  42.716  1.00 33.80 ? 67  GLU   B OE1  1 
ATOM   5698  O  OE2  . GLU   B 1 68  ? 27.400  53.272  44.805  1.00 43.17 ? 67  GLU   B OE2  1 
ATOM   5699  H  H    . GLU   B 1 68  ? 31.200  50.544  42.978  1.00 40.94 ? 67  GLU   B H    1 
ATOM   5700  H  HA   . GLU   B 1 68  ? 29.737  48.963  44.421  1.00 38.17 ? 67  GLU   B HA   1 
ATOM   5701  H  HB2  . GLU   B 1 68  ? 28.854  50.547  42.266  1.00 36.93 ? 67  GLU   B HB2  1 
ATOM   5702  H  HB3  . GLU   B 1 68  ? 27.882  49.854  43.316  1.00 36.93 ? 67  GLU   B HB3  1 
ATOM   5703  H  HG2  . GLU   B 1 68  ? 28.788  51.210  45.011  1.00 40.58 ? 67  GLU   B HG2  1 
ATOM   5704  H  HG3  . GLU   B 1 68  ? 29.692  51.935  43.924  1.00 40.58 ? 67  GLU   B HG3  1 
ATOM   5705  N  N    . ALA   B 1 69  ? 30.056  48.002  41.363  1.00 27.31 ? 68  ALA   B N    1 
ATOM   5706  C  CA   . ALA   B 1 69  ? 29.880  46.853  40.473  1.00 27.84 ? 68  ALA   B CA   1 
ATOM   5707  C  C    . ALA   B 1 69  ? 30.633  45.634  40.989  1.00 27.79 ? 68  ALA   B C    1 
ATOM   5708  O  O    . ALA   B 1 69  ? 30.071  44.536  41.087  1.00 28.99 ? 68  ALA   B O    1 
ATOM   5709  C  CB   . ALA   B 1 69  ? 30.350  47.216  39.065  1.00 30.17 ? 68  ALA   B CB   1 
ATOM   5710  H  H    . ALA   B 1 69  ? 30.454  48.674  41.004  1.00 32.77 ? 68  ALA   B H    1 
ATOM   5711  H  HA   . ALA   B 1 69  ? 28.937  46.628  40.433  1.00 33.41 ? 68  ALA   B HA   1 
ATOM   5712  H  HB1  . ALA   B 1 69  ? 30.365  46.414  38.521  1.00 36.21 ? 68  ALA   B HB1  1 
ATOM   5713  H  HB2  . ALA   B 1 69  ? 29.736  47.863  38.684  1.00 36.21 ? 68  ALA   B HB2  1 
ATOM   5714  H  HB3  . ALA   B 1 69  ? 31.240  47.597  39.119  1.00 36.21 ? 68  ALA   B HB3  1 
ATOM   5715  N  N    . PHE   B 1 70  ? 31.910  45.814  41.346  1.00 32.03 ? 69  PHE   B N    1 
ATOM   5716  C  CA   . PHE   B 1 70  ? 32.704  44.688  41.822  1.00 35.11 ? 69  PHE   B CA   1 
ATOM   5717  C  C    . PHE   B 1 70  ? 32.140  44.108  43.107  1.00 30.50 ? 69  PHE   B C    1 
ATOM   5718  O  O    . PHE   B 1 70  ? 32.114  42.888  43.277  1.00 31.55 ? 69  PHE   B O    1 
ATOM   5719  C  CB   . PHE   B 1 70  ? 34.150  45.094  42.064  1.00 34.80 ? 69  PHE   B CB   1 
ATOM   5720  C  CG   . PHE   B 1 70  ? 35.021  43.951  42.505  1.00 39.22 ? 69  PHE   B CG   1 
ATOM   5721  C  CD1  . PHE   B 1 70  ? 35.355  42.930  41.623  1.00 41.68 ? 69  PHE   B CD1  1 
ATOM   5722  C  CD2  . PHE   B 1 70  ? 35.476  43.874  43.812  1.00 45.68 ? 69  PHE   B CD2  1 
ATOM   5723  C  CE1  . PHE   B 1 70  ? 36.159  41.870  42.029  1.00 41.10 ? 69  PHE   B CE1  1 
ATOM   5724  C  CE2  . PHE   B 1 70  ? 36.276  42.819  44.223  1.00 49.15 ? 69  PHE   B CE2  1 
ATOM   5725  C  CZ   . PHE   B 1 70  ? 36.612  41.812  43.324  1.00 48.07 ? 69  PHE   B CZ   1 
ATOM   5726  H  H    . PHE   B 1 70  ? 32.329  46.565  41.321  1.00 38.44 ? 69  PHE   B H    1 
ATOM   5727  H  HA   . PHE   B 1 70  ? 32.684  44.013  41.126  1.00 42.13 ? 69  PHE   B HA   1 
ATOM   5728  H  HB2  . PHE   B 1 70  ? 34.518  45.448  41.239  1.00 41.76 ? 69  PHE   B HB2  1 
ATOM   5729  H  HB3  . PHE   B 1 70  ? 34.174  45.772  42.757  1.00 41.76 ? 69  PHE   B HB3  1 
ATOM   5730  H  HD1  . PHE   B 1 70  ? 35.036  42.955  40.750  1.00 50.02 ? 69  PHE   B HD1  1 
ATOM   5731  H  HD2  . PHE   B 1 70  ? 35.243  44.539  44.420  1.00 54.81 ? 69  PHE   B HD2  1 
ATOM   5732  H  HE1  . PHE   B 1 70  ? 36.390  41.202  41.424  1.00 49.32 ? 69  PHE   B HE1  1 
ATOM   5733  H  HE2  . PHE   B 1 70  ? 36.587  42.784  45.099  1.00 58.98 ? 69  PHE   B HE2  1 
ATOM   5734  H  HZ   . PHE   B 1 70  ? 37.142  41.099  43.600  1.00 57.69 ? 69  PHE   B HZ   1 
ATOM   5735  N  N    . GLU   B 1 71  ? 31.723  44.967  44.048  1.00 30.11 ? 70  GLU   B N    1 
ATOM   5736  C  CA   . GLU   B 1 71  ? 31.148  44.468  45.295  1.00 27.40 ? 70  GLU   B CA   1 
ATOM   5737  C  C    . GLU   B 1 71  ? 29.841  43.720  45.053  1.00 32.14 ? 70  GLU   B C    1 
ATOM   5738  O  O    . GLU   B 1 71  ? 29.495  42.805  45.810  1.00 29.12 ? 70  GLU   B O    1 
ATOM   5739  C  CB   . GLU   B 1 71  ? 30.931  45.614  46.289  1.00 35.19 ? 70  GLU   B CB   1 
ATOM   5740  C  CG   . GLU   B 1 71  ? 32.241  46.261  46.747  1.00 35.87 ? 70  GLU   B CG   1 
ATOM   5741  C  CD   . GLU   B 1 71  ? 32.055  47.340  47.829  1.00 50.59 ? 70  GLU   B CD   1 
ATOM   5742  O  OE1  . GLU   B 1 71  ? 30.907  47.577  48.263  1.00 48.72 ? 70  GLU   B OE1  1 
ATOM   5743  O  OE2  . GLU   B 1 71  ? 33.067  47.945  48.255  1.00 47.91 ? 70  GLU   B OE2  1 
ATOM   5744  H  H    . GLU   B 1 71  ? 31.763  45.824  43.987  1.00 36.13 ? 70  GLU   B H    1 
ATOM   5745  H  HA   . GLU   B 1 71  ? 31.778  43.849  45.695  1.00 32.88 ? 70  GLU   B HA   1 
ATOM   5746  H  HB2  . GLU   B 1 71  ? 30.390  46.300  45.867  1.00 42.22 ? 70  GLU   B HB2  1 
ATOM   5747  H  HB3  . GLU   B 1 71  ? 30.477  45.270  47.074  1.00 42.22 ? 70  GLU   B HB3  1 
ATOM   5748  H  HG2  . GLU   B 1 71  ? 32.818  45.572  47.113  1.00 43.05 ? 70  GLU   B HG2  1 
ATOM   5749  H  HG3  . GLU   B 1 71  ? 32.667  46.679  45.983  1.00 43.05 ? 70  GLU   B HG3  1 
ATOM   5750  N  N    . TYR   B 1 72  ? 29.098  44.085  44.012  1.00 26.23 ? 71  TYR   B N    1 
ATOM   5751  C  CA   . TYR   B 1 72  ? 27.816  43.441  43.785  1.00 28.10 ? 71  TYR   B CA   1 
ATOM   5752  C  C    . TYR   B 1 72  ? 27.968  42.148  42.964  1.00 26.40 ? 71  TYR   B C    1 
ATOM   5753  O  O    . TYR   B 1 72  ? 27.319  41.146  43.277  1.00 27.61 ? 71  TYR   B O    1 
ATOM   5754  C  CB   . TYR   B 1 72  ? 26.848  44.412  43.088  1.00 27.42 ? 71  TYR   B CB   1 
ATOM   5755  C  CG   . TYR   B 1 72  ? 25.410  43.958  43.207  1.00 24.02 ? 71  TYR   B CG   1 
ATOM   5756  C  CD1  . TYR   B 1 72  ? 24.793  43.878  44.464  1.00 23.90 ? 71  TYR   B CD1  1 
ATOM   5757  C  CD2  . TYR   B 1 72  ? 24.668  43.595  42.089  1.00 26.62 ? 71  TYR   B CD2  1 
ATOM   5758  C  CE1  . TYR   B 1 72  ? 23.496  43.443  44.606  1.00 29.33 ? 71  TYR   B CE1  1 
ATOM   5759  C  CE2  . TYR   B 1 72  ? 23.337  43.155  42.225  1.00 27.85 ? 71  TYR   B CE2  1 
ATOM   5760  C  CZ   . TYR   B 1 72  ? 22.773  43.072  43.486  1.00 30.78 ? 71  TYR   B CZ   1 
ATOM   5761  O  OH   . TYR   B 1 72  ? 21.482  42.628  43.671  1.00 27.31 ? 71  TYR   B OH   1 
ATOM   5762  H  H    . TYR   B 1 72  ? 29.312  44.689  43.438  1.00 31.47 ? 71  TYR   B H    1 
ATOM   5763  H  HA   . TYR   B 1 72  ? 27.419  43.208  44.639  1.00 33.73 ? 71  TYR   B HA   1 
ATOM   5764  H  HB2  . TYR   B 1 72  ? 26.925  45.288  43.498  1.00 32.91 ? 71  TYR   B HB2  1 
ATOM   5765  H  HB3  . TYR   B 1 72  ? 27.073  44.465  42.146  1.00 32.91 ? 71  TYR   B HB3  1 
ATOM   5766  H  HD1  . TYR   B 1 72  ? 25.273  44.125  45.221  1.00 28.68 ? 71  TYR   B HD1  1 
ATOM   5767  H  HD2  . TYR   B 1 72  ? 25.053  43.642  41.244  1.00 31.95 ? 71  TYR   B HD2  1 
ATOM   5768  H  HE1  . TYR   B 1 72  ? 23.107  43.398  45.449  1.00 35.20 ? 71  TYR   B HE1  1 
ATOM   5769  H  HE2  . TYR   B 1 72  ? 22.840  42.923  41.474  1.00 33.42 ? 71  TYR   B HE2  1 
ATOM   5770  H  HH   . TYR   B 1 72  ? 21.213  42.840  44.438  1.00 32.78 ? 71  TYR   B HH   1 
ATOM   5771  N  N    . TYR   B 1 73  ? 28.824  42.148  41.945  1.00 26.49 ? 72  TYR   B N    1 
ATOM   5772  C  CA   . TYR   B 1 73  ? 28.924  41.019  41.008  1.00 24.99 ? 72  TYR   B CA   1 
ATOM   5773  C  C    . TYR   B 1 73  ? 30.145  40.132  41.213  1.00 31.74 ? 72  TYR   B C    1 
ATOM   5774  O  O    . TYR   B 1 73  ? 30.172  39.013  40.681  1.00 31.94 ? 72  TYR   B O    1 
ATOM   5775  C  CB   . TYR   B 1 73  ? 28.953  41.527  39.561  1.00 26.78 ? 72  TYR   B CB   1 
ATOM   5776  C  CG   . TYR   B 1 73  ? 27.697  42.274  39.175  1.00 28.44 ? 72  TYR   B CG   1 
ATOM   5777  C  CD1  . TYR   B 1 73  ? 26.473  41.631  39.124  1.00 23.93 ? 72  TYR   B CD1  1 
ATOM   5778  C  CD2  . TYR   B 1 73  ? 27.741  43.641  38.891  1.00 29.58 ? 72  TYR   B CD2  1 
ATOM   5779  C  CE1  . TYR   B 1 73  ? 25.309  42.329  38.792  1.00 26.15 ? 72  TYR   B CE1  1 
ATOM   5780  C  CE2  . TYR   B 1 73  ? 26.589  44.337  38.553  1.00 29.20 ? 72  TYR   B CE2  1 
ATOM   5781  C  CZ   . TYR   B 1 73  ? 25.392  43.682  38.525  1.00 29.67 ? 72  TYR   B CZ   1 
ATOM   5782  O  OH   . TYR   B 1 73  ? 24.276  44.378  38.207  1.00 27.24 ? 72  TYR   B OH   1 
ATOM   5783  H  H    . TYR   B 1 73  ? 29.365  42.793  41.769  1.00 31.79 ? 72  TYR   B H    1 
ATOM   5784  H  HA   . TYR   B 1 73  ? 28.135  40.469  41.136  1.00 29.99 ? 72  TYR   B HA   1 
ATOM   5785  H  HB2  . TYR   B 1 73  ? 29.705  42.130  39.454  1.00 32.13 ? 72  TYR   B HB2  1 
ATOM   5786  H  HB3  . TYR   B 1 73  ? 29.047  40.769  38.962  1.00 32.13 ? 72  TYR   B HB3  1 
ATOM   5787  H  HD1  . TYR   B 1 73  ? 26.424  40.722  39.312  1.00 28.72 ? 72  TYR   B HD1  1 
ATOM   5788  H  HD2  . TYR   B 1 73  ? 28.553  44.092  38.930  1.00 35.50 ? 72  TYR   B HD2  1 
ATOM   5789  H  HE1  . TYR   B 1 73  ? 24.491  41.889  38.752  1.00 31.38 ? 72  TYR   B HE1  1 
ATOM   5790  H  HE2  . TYR   B 1 73  ? 26.632  45.242  38.346  1.00 35.04 ? 72  TYR   B HE2  1 
ATOM   5791  H  HH   . TYR   B 1 73  ? 24.482  45.078  37.792  1.00 32.68 ? 72  TYR   B HH   1 
ATOM   5792  N  N    . HIS   B 1 74  ? 31.158  40.609  41.932  1.00 32.08 ? 73  HIS   B N    1 
ATOM   5793  C  CA   . HIS   B 1 74  ? 32.417  39.884  42.122  1.00 32.94 ? 73  HIS   B CA   1 
ATOM   5794  C  C    . HIS   B 1 74  ? 33.116  39.568  40.799  1.00 34.81 ? 73  HIS   B C    1 
ATOM   5795  O  O    . HIS   B 1 74  ? 33.737  38.520  40.633  1.00 36.91 ? 73  HIS   B O    1 
ATOM   5796  C  CB   . HIS   B 1 74  ? 32.198  38.602  42.928  1.00 33.43 ? 73  HIS   B CB   1 
ATOM   5797  C  CG   . HIS   B 1 74  ? 31.872  38.840  44.362  1.00 32.55 ? 73  HIS   B CG   1 
ATOM   5798  N  ND1  . HIS   B 1 74  ? 31.745  37.817  45.280  1.00 31.39 ? 73  HIS   B ND1  1 
ATOM   5799  C  CD2  . HIS   B 1 74  ? 31.659  39.988  45.048  1.00 28.84 ? 73  HIS   B CD2  1 
ATOM   5800  C  CE1  . HIS   B 1 74  ? 31.459  38.325  46.464  1.00 30.88 ? 73  HIS   B CE1  1 
ATOM   5801  N  NE2  . HIS   B 1 74  ? 31.410  39.641  46.351  1.00 31.58 ? 73  HIS   B NE2  1 
ATOM   5802  H  H    . HIS   B 1 74  ? 31.142  41.370  42.332  1.00 38.49 ? 73  HIS   B H    1 
ATOM   5803  H  HA   . HIS   B 1 74  ? 33.012  40.466  42.621  1.00 39.53 ? 73  HIS   B HA   1 
ATOM   5804  H  HB2  . HIS   B 1 74  ? 31.461  38.109  42.535  1.00 40.11 ? 73  HIS   B HB2  1 
ATOM   5805  H  HB3  . HIS   B 1 74  ? 33.009  38.070  42.894  1.00 40.11 ? 73  HIS   B HB3  1 
ATOM   5806  H  HD2  . HIS   B 1 74  ? 31.679  40.850  44.701  1.00 34.61 ? 73  HIS   B HD2  1 
ATOM   5807  H  HE1  . HIS   B 1 74  ? 31.317  37.840  47.245  1.00 37.05 ? 73  HIS   B HE1  1 
ATOM   5808  H  HE2  . HIS   B 1 74  ? 31.248  40.192  46.992  1.00 37.90 ? 73  HIS   B HE2  1 
ATOM   5809  N  N    . THR   B 1 75  ? 33.060  40.504  39.866  1.00 31.75 ? 74  THR   B N    1 
ATOM   5810  C  CA   . THR   B 1 75  ? 33.809  40.395  38.632  1.00 36.19 ? 74  THR   B CA   1 
ATOM   5811  C  C    . THR   B 1 75  ? 34.206  41.797  38.209  1.00 35.72 ? 74  THR   B C    1 
ATOM   5812  O  O    . THR   B 1 75  ? 33.492  42.763  38.485  1.00 35.53 ? 74  THR   B O    1 
ATOM   5813  C  CB   . THR   B 1 75  ? 32.997  39.697  37.536  1.00 30.81 ? 74  THR   B CB   1 
ATOM   5814  O  OG1  . THR   B 1 75  ? 33.805  39.578  36.356  1.00 40.33 ? 74  THR   B OG1  1 
ATOM   5815  C  CG2  . THR   B 1 75  ? 31.743  40.478  37.233  1.00 35.95 ? 74  THR   B CG2  1 
ATOM   5816  H  H    . THR   B 1 75  ? 32.588  41.220  39.926  1.00 38.11 ? 74  THR   B H    1 
ATOM   5817  H  HA   . THR   B 1 75  ? 34.615  39.872  38.768  1.00 43.43 ? 74  THR   B HA   1 
ATOM   5818  H  HB   . THR   B 1 75  ? 32.730  38.811  37.828  1.00 36.97 ? 74  THR   B HB   1 
ATOM   5819  H  HG1  . THR   B 1 75  ? 33.332  39.690  35.671  1.00 48.40 ? 74  THR   B HG1  1 
ATOM   5820  H  HG21 . THR   B 1 75  ? 31.066  39.890  36.863  1.00 43.14 ? 74  THR   B HG21 1 
ATOM   5821  H  HG22 . THR   B 1 75  ? 31.398  40.881  38.046  1.00 43.14 ? 74  THR   B HG22 1 
ATOM   5822  H  HG23 . THR   B 1 75  ? 31.935  41.180  36.592  1.00 43.14 ? 74  THR   B HG23 1 
ATOM   5823  N  N    . THR   B 1 76  ? 35.353  41.894  37.543  1.00 35.47 ? 75  THR   B N    1 
ATOM   5824  C  CA   . THR   B 1 76  ? 35.813  43.128  36.930  1.00 42.62 ? 75  THR   B CA   1 
ATOM   5825  C  C    . THR   B 1 76  ? 35.751  43.077  35.408  1.00 38.93 ? 75  THR   B C    1 
ATOM   5826  O  O    . THR   B 1 76  ? 36.190  44.029  34.756  1.00 45.87 ? 75  THR   B O    1 
ATOM   5827  C  CB   . THR   B 1 76  ? 37.250  43.436  37.364  1.00 45.32 ? 75  THR   B CB   1 
ATOM   5828  O  OG1  . THR   B 1 76  ? 38.103  42.350  36.991  1.00 48.00 ? 75  THR   B OG1  1 
ATOM   5829  C  CG2  . THR   B 1 76  ? 37.314  43.633  38.877  1.00 47.60 ? 75  THR   B CG2  1 
ATOM   5830  H  H    . THR   B 1 76  ? 35.896  41.237  37.432  1.00 42.57 ? 75  THR   B H    1 
ATOM   5831  H  HA   . THR   B 1 76  ? 35.248  43.854  37.237  1.00 51.15 ? 75  THR   B HA   1 
ATOM   5832  H  HB   . THR   B 1 76  ? 37.556  44.250  36.935  1.00 54.39 ? 75  THR   B HB   1 
ATOM   5833  H  HG1  . THR   B 1 76  ? 38.385  41.957  37.678  1.00 57.60 ? 75  THR   B HG1  1 
ATOM   5834  H  HG21 . THR   B 1 76  ? 38.133  44.094  39.117  1.00 57.12 ? 75  THR   B HG21 1 
ATOM   5835  H  HG22 . THR   B 1 76  ? 36.557  44.161  39.175  1.00 57.12 ? 75  THR   B HG22 1 
ATOM   5836  H  HG23 . THR   B 1 76  ? 37.294  42.773  39.324  1.00 57.12 ? 75  THR   B HG23 1 
ATOM   5837  N  N    . ASP   B 1 77  ? 35.223  41.991  34.830  1.00 37.03 ? 76  ASP   B N    1 
ATOM   5838  C  CA   . ASP   B 1 77  ? 35.049  41.819  33.393  1.00 37.66 ? 76  ASP   B CA   1 
ATOM   5839  C  C    . ASP   B 1 77  ? 34.226  42.960  32.807  1.00 36.55 ? 76  ASP   B C    1 
ATOM   5840  O  O    . ASP   B 1 77  ? 33.035  43.088  33.102  1.00 35.70 ? 76  ASP   B O    1 
ATOM   5841  C  CB   . ASP   B 1 77  ? 34.413  40.450  33.161  1.00 39.30 ? 76  ASP   B CB   1 
ATOM   5842  C  CG   . ASP   B 1 77  ? 34.170  40.143  31.707  1.00 36.04 ? 76  ASP   B CG   1 
ATOM   5843  O  OD1  . ASP   B 1 77  ? 34.431  41.008  30.838  1.00 41.05 ? 76  ASP   B OD1  1 
ATOM   5844  O  OD2  . ASP   B 1 77  ? 33.713  39.016  31.444  1.00 39.03 ? 76  ASP   B OD2  1 
ATOM   5845  H  H    . ASP   B 1 77  ? 34.946  41.310  35.276  1.00 44.44 ? 76  ASP   B H    1 
ATOM   5846  H  HA   . ASP   B 1 77  ? 35.897  41.854  32.924  1.00 45.20 ? 76  ASP   B HA   1 
ATOM   5847  H  HB2  . ASP   B 1 77  ? 35.003  39.766  33.515  1.00 47.17 ? 76  ASP   B HB2  1 
ATOM   5848  H  HB3  . ASP   B 1 77  ? 33.558  40.419  33.618  1.00 47.17 ? 76  ASP   B HB3  1 
ATOM   5849  N  N    . PRO   B 1 78  ? 34.829  43.807  31.968  1.00 39.54 ? 77  PRO   B N    1 
ATOM   5850  C  CA   . PRO   B 1 78  ? 34.106  44.994  31.488  1.00 38.38 ? 77  PRO   B CA   1 
ATOM   5851  C  C    . PRO   B 1 78  ? 32.918  44.656  30.618  1.00 37.08 ? 77  PRO   B C    1 
ATOM   5852  O  O    . PRO   B 1 78  ? 32.034  45.503  30.451  1.00 40.36 ? 77  PRO   B O    1 
ATOM   5853  C  CB   . PRO   B 1 78  ? 35.175  45.768  30.697  1.00 44.54 ? 77  PRO   B CB   1 
ATOM   5854  C  CG   . PRO   B 1 78  ? 36.502  45.161  31.126  1.00 46.41 ? 77  PRO   B CG   1 
ATOM   5855  C  CD   . PRO   B 1 78  ? 36.183  43.724  31.388  1.00 41.55 ? 77  PRO   B CD   1 
ATOM   5856  H  HA   . PRO   B 1 78  ? 33.814  45.535  32.239  1.00 46.06 ? 77  PRO   B HA   1 
ATOM   5857  H  HB2  . PRO   B 1 78  ? 35.030  45.649  29.745  1.00 53.45 ? 77  PRO   B HB2  1 
ATOM   5858  H  HB3  . PRO   B 1 78  ? 35.135  46.710  30.923  1.00 53.45 ? 77  PRO   B HB3  1 
ATOM   5859  H  HG2  . PRO   B 1 78  ? 37.155  45.249  30.414  1.00 55.70 ? 77  PRO   B HG2  1 
ATOM   5860  H  HG3  . PRO   B 1 78  ? 36.825  45.599  31.928  1.00 55.70 ? 77  PRO   B HG3  1 
ATOM   5861  H  HD2  . PRO   B 1 78  ? 36.180  43.211  30.565  1.00 49.86 ? 77  PRO   B HD2  1 
ATOM   5862  H  HD3  . PRO   B 1 78  ? 36.810  43.336  32.018  1.00 49.86 ? 77  PRO   B HD3  1 
ATOM   5863  N  N    . SER   B 1 79  ? 32.865  43.453  30.054  1.00 36.10 ? 78  SER   B N    1 
ATOM   5864  C  CA   . SER   B 1 79  ? 31.731  43.042  29.244  1.00 33.03 ? 78  SER   B CA   1 
ATOM   5865  C  C    . SER   B 1 79  ? 30.578  42.453  30.045  1.00 30.76 ? 78  SER   B C    1 
ATOM   5866  O  O    . SER   B 1 79  ? 29.514  42.212  29.471  1.00 31.81 ? 78  SER   B O    1 
ATOM   5867  C  CB   . SER   B 1 79  ? 32.184  41.999  28.214  1.00 36.87 ? 78  SER   B CB   1 
ATOM   5868  O  OG   . SER   B 1 79  ? 32.393  40.739  28.844  1.00 36.26 ? 78  SER   B OG   1 
ATOM   5869  H  H    . SER   B 1 79  ? 33.478  42.855  30.129  1.00 43.32 ? 78  SER   B H    1 
ATOM   5870  H  HA   . SER   B 1 79  ? 31.397  43.826  28.780  1.00 39.63 ? 78  SER   B HA   1 
ATOM   5871  H  HB2  . SER   B 1 79  ? 31.498  41.905  27.535  1.00 44.25 ? 78  SER   B HB2  1 
ATOM   5872  H  HB3  . SER   B 1 79  ? 33.014  42.293  27.808  1.00 44.25 ? 78  SER   B HB3  1 
ATOM   5873  H  HG   . SER   B 1 79  ? 32.704  40.189  28.290  1.00 43.51 ? 78  SER   B HG   1 
ATOM   5874  N  N    . PHE   B 1 80  ? 30.747  42.218  31.349  1.00 33.84 ? 79  PHE   B N    1 
ATOM   5875  C  CA   . PHE   B 1 80  ? 29.735  41.468  32.096  1.00 36.59 ? 79  PHE   B CA   1 
ATOM   5876  C  C    . PHE   B 1 80  ? 28.377  42.166  32.104  1.00 35.11 ? 79  PHE   B C    1 
ATOM   5877  O  O    . PHE   B 1 80  ? 27.353  41.555  31.775  1.00 26.23 ? 79  PHE   B O    1 
ATOM   5878  C  CB   . PHE   B 1 80  ? 30.202  41.240  33.519  1.00 31.57 ? 79  PHE   B CB   1 
ATOM   5879  C  CG   . PHE   B 1 80  ? 29.228  40.458  34.369  1.00 27.41 ? 79  PHE   B CG   1 
ATOM   5880  C  CD1  . PHE   B 1 80  ? 29.255  39.076  34.396  1.00 33.38 ? 79  PHE   B CD1  1 
ATOM   5881  C  CD2  . PHE   B 1 80  ? 28.283  41.109  35.131  1.00 28.31 ? 79  PHE   B CD2  1 
ATOM   5882  C  CE1  . PHE   B 1 80  ? 28.372  38.358  35.200  1.00 29.74 ? 79  PHE   B CE1  1 
ATOM   5883  C  CE2  . PHE   B 1 80  ? 27.395  40.401  35.920  1.00 30.67 ? 79  PHE   B CE2  1 
ATOM   5884  C  CZ   . PHE   B 1 80  ? 27.441  39.019  35.948  1.00 28.80 ? 79  PHE   B CZ   1 
ATOM   5885  H  H    . PHE   B 1 80  ? 31.422  42.477  31.815  1.00 40.61 ? 79  PHE   B H    1 
ATOM   5886  H  HA   . PHE   B 1 80  ? 29.625  40.611  31.655  1.00 43.91 ? 79  PHE   B HA   1 
ATOM   5887  H  HB2  . PHE   B 1 80  ? 31.036  40.746  33.497  1.00 37.88 ? 79  PHE   B HB2  1 
ATOM   5888  H  HB3  . PHE   B 1 80  ? 30.337  42.101  33.944  1.00 37.88 ? 79  PHE   B HB3  1 
ATOM   5889  H  HD1  . PHE   B 1 80  ? 29.871  38.618  33.870  1.00 40.06 ? 79  PHE   B HD1  1 
ATOM   5890  H  HD2  . PHE   B 1 80  ? 28.241  42.038  35.116  1.00 33.98 ? 79  PHE   B HD2  1 
ATOM   5891  H  HE1  . PHE   B 1 80  ? 28.417  37.430  35.227  1.00 35.69 ? 79  PHE   B HE1  1 
ATOM   5892  H  HE2  . PHE   B 1 80  ? 26.765  40.855  36.432  1.00 36.80 ? 79  PHE   B HE2  1 
ATOM   5893  H  HZ   . PHE   B 1 80  ? 26.841  38.542  36.475  1.00 34.55 ? 79  PHE   B HZ   1 
ATOM   5894  N  N    . LEU   B 1 81  ? 28.335  43.433  32.528  1.00 34.73 ? 80  LEU   B N    1 
ATOM   5895  C  CA   . LEU   B 1 81  ? 27.043  44.105  32.645  1.00 35.19 ? 80  LEU   B CA   1 
ATOM   5896  C  C    . LEU   B 1 81  ? 26.304  44.088  31.319  1.00 28.10 ? 80  LEU   B C    1 
ATOM   5897  O  O    . LEU   B 1 81  ? 25.092  43.858  31.279  1.00 27.17 ? 80  LEU   B O    1 
ATOM   5898  C  CB   . LEU   B 1 81  ? 27.233  45.541  33.132  1.00 38.92 ? 80  LEU   B CB   1 
ATOM   5899  C  CG   . LEU   B 1 81  ? 26.756  45.828  34.545  1.00 47.20 ? 80  LEU   B CG   1 
ATOM   5900  C  CD1  . LEU   B 1 81  ? 27.250  47.204  34.993  1.00 47.64 ? 80  LEU   B CD1  1 
ATOM   5901  C  CD2  . LEU   B 1 81  ? 25.236  45.740  34.623  1.00 43.04 ? 80  LEU   B CD2  1 
ATOM   5902  H  H    . LEU   B 1 81  ? 29.017  43.908  32.747  1.00 41.68 ? 80  LEU   B H    1 
ATOM   5903  H  HA   . LEU   B 1 81  ? 26.506  43.637  33.303  1.00 42.22 ? 80  LEU   B HA   1 
ATOM   5904  H  HB2  . LEU   B 1 81  ? 28.180  45.750  33.099  1.00 46.70 ? 80  LEU   B HB2  1 
ATOM   5905  H  HB3  . LEU   B 1 81  ? 26.743  46.130  32.537  1.00 46.70 ? 80  LEU   B HB3  1 
ATOM   5906  H  HG   . LEU   B 1 81  ? 27.118  45.164  35.152  1.00 56.64 ? 80  LEU   B HG   1 
ATOM   5907  H  HD11 . LEU   B 1 81  ? 26.938  47.373  35.895  1.00 57.17 ? 80  LEU   B HD11 1 
ATOM   5908  H  HD12 . LEU   B 1 81  ? 28.220  47.213  34.971  1.00 57.17 ? 80  LEU   B HD12 1 
ATOM   5909  H  HD13 . LEU   B 1 81  ? 26.899  47.877  34.389  1.00 57.17 ? 80  LEU   B HD13 1 
ATOM   5910  H  HD21 . LEU   B 1 81  ? 24.955  45.927  35.532  1.00 51.65 ? 80  LEU   B HD21 1 
ATOM   5911  H  HD22 . LEU   B 1 81  ? 24.850  46.392  34.017  1.00 51.65 ? 80  LEU   B HD22 1 
ATOM   5912  H  HD23 . LEU   B 1 81  ? 24.958  44.847  34.368  1.00 51.65 ? 80  LEU   B HD23 1 
ATOM   5913  N  N    . GLY   B 1 82  ? 27.022  44.301  30.217  1.00 30.08 ? 81  GLY   B N    1 
ATOM   5914  C  CA   . GLY   B 1 82  ? 26.381  44.282  28.914  1.00 35.77 ? 81  GLY   B CA   1 
ATOM   5915  C  C    . GLY   B 1 82  ? 25.829  42.915  28.551  1.00 31.06 ? 81  GLY   B C    1 
ATOM   5916  O  O    . GLY   B 1 82  ? 24.726  42.806  28.015  1.00 30.32 ? 81  GLY   B O    1 
ATOM   5917  H  H    . GLY   B 1 82  ? 27.868  44.457  30.200  1.00 36.10 ? 81  GLY   B H    1 
ATOM   5918  H  HA2  . GLY   B 1 82  ? 25.648  44.917  28.909  1.00 42.93 ? 81  GLY   B HA2  1 
ATOM   5919  H  HA3  . GLY   B 1 82  ? 27.026  44.539  28.237  1.00 42.93 ? 81  GLY   B HA3  1 
ATOM   5920  N  N    . ARG   B 1 83  ? 26.572  41.856  28.867  1.00 35.50 ? 82  ARG   B N    1 
ATOM   5921  C  CA   . ARG   B 1 83  ? 26.069  40.507  28.621  1.00 28.73 ? 82  ARG   B CA   1 
ATOM   5922  C  C    . ARG   B 1 83  ? 24.876  40.190  29.512  1.00 29.07 ? 82  ARG   B C    1 
ATOM   5923  O  O    . ARG   B 1 83  ? 23.887  39.599  29.050  1.00 25.19 ? 82  ARG   B O    1 
ATOM   5924  C  CB   . ARG   B 1 83  ? 27.212  39.515  28.821  1.00 28.51 ? 82  ARG   B CB   1 
ATOM   5925  C  CG   . ARG   B 1 83  ? 28.216  39.634  27.655  1.00 32.72 ? 82  ARG   B CG   1 
ATOM   5926  C  CD   . ARG   B 1 83  ? 29.358  38.624  27.669  1.00 35.64 ? 82  ARG   B CD   1 
ATOM   5927  N  NE   . ARG   B 1 83  ? 30.196  38.734  28.852  1.00 36.08 ? 82  ARG   B NE   1 
ATOM   5928  C  CZ   . ARG   B 1 83  ? 30.084  37.937  29.900  1.00 31.74 ? 82  ARG   B CZ   1 
ATOM   5929  N  NH1  . ARG   B 1 83  ? 29.115  37.046  29.975  1.00 29.54 ? 82  ARG   B NH1  1 
ATOM   5930  N  NH2  . ARG   B 1 83  ? 30.949  38.055  30.902  1.00 34.46 ? 82  ARG   B NH2  1 
ATOM   5931  H  H    . ARG   B 1 83  ? 27.356  41.890  29.219  1.00 42.60 ? 82  ARG   B H    1 
ATOM   5932  H  HA   . ARG   B 1 83  ? 25.759  40.427  27.705  1.00 34.48 ? 82  ARG   B HA   1 
ATOM   5933  H  HB2  . ARG   B 1 83  ? 27.673  39.710  29.652  1.00 34.21 ? 82  ARG   B HB2  1 
ATOM   5934  H  HB3  . ARG   B 1 83  ? 26.861  38.611  28.841  1.00 34.21 ? 82  ARG   B HB3  1 
ATOM   5935  H  HG2  . ARG   B 1 83  ? 27.733  39.511  26.822  1.00 39.26 ? 82  ARG   B HG2  1 
ATOM   5936  H  HG3  . ARG   B 1 83  ? 28.613  40.518  27.681  1.00 39.26 ? 82  ARG   B HG3  1 
ATOM   5937  H  HD2  . ARG   B 1 83  ? 28.987  37.728  27.648  1.00 42.77 ? 82  ARG   B HD2  1 
ATOM   5938  H  HD3  . ARG   B 1 83  ? 29.918  38.769  26.891  1.00 42.77 ? 82  ARG   B HD3  1 
ATOM   5939  H  HE   . ARG   B 1 83  ? 30.796  39.350  28.870  1.00 43.29 ? 82  ARG   B HE   1 
ATOM   5940  H  HH11 . ARG   B 1 83  ? 29.055  36.533  30.663  1.00 35.45 ? 82  ARG   B HH11 1 
ATOM   5941  H  HH12 . ARG   B 1 83  ? 28.544  36.976  29.336  1.00 35.45 ? 82  ARG   B HH12 1 
ATOM   5942  H  HH21 . ARG   B 1 83  ? 31.573  38.645  30.864  1.00 41.35 ? 82  ARG   B HH21 1 
ATOM   5943  H  HH22 . ARG   B 1 83  ? 30.885  37.541  31.588  1.00 41.35 ? 82  ARG   B HH22 1 
ATOM   5944  N  N    . TYR   B 1 84  ? 24.931  40.621  30.780  1.00 24.71 ? 83  TYR   B N    1 
ATOM   5945  C  CA   . TYR   B 1 84  ? 23.814  40.415  31.689  1.00 25.38 ? 83  TYR   B CA   1 
ATOM   5946  C  C    . TYR   B 1 84  ? 22.575  41.143  31.176  1.00 21.80 ? 83  TYR   B C    1 
ATOM   5947  O  O    . TYR   B 1 84  ? 21.485  40.566  31.092  1.00 23.95 ? 83  TYR   B O    1 
ATOM   5948  C  CB   . TYR   B 1 84  ? 24.253  40.857  33.102  1.00 27.68 ? 83  TYR   B CB   1 
ATOM   5949  C  CG   . TYR   B 1 84  ? 23.187  41.026  34.158  1.00 23.39 ? 83  TYR   B CG   1 
ATOM   5950  C  CD1  . TYR   B 1 84  ? 22.087  40.203  34.223  1.00 23.09 ? 83  TYR   B CD1  1 
ATOM   5951  C  CD2  . TYR   B 1 84  ? 23.294  42.041  35.110  1.00 27.22 ? 83  TYR   B CD2  1 
ATOM   5952  C  CE1  . TYR   B 1 84  ? 21.116  40.376  35.190  1.00 26.18 ? 83  TYR   B CE1  1 
ATOM   5953  C  CE2  . TYR   B 1 84  ? 22.317  42.227  36.073  1.00 24.34 ? 83  TYR   B CE2  1 
ATOM   5954  C  CZ   . TYR   B 1 84  ? 21.236  41.400  36.104  1.00 27.33 ? 83  TYR   B CZ   1 
ATOM   5955  O  OH   . TYR   B 1 84  ? 20.275  41.576  37.054  1.00 33.37 ? 83  TYR   B OH   1 
ATOM   5956  H  H    . TYR   B 1 84  ? 25.601  41.031  31.129  1.00 29.65 ? 83  TYR   B H    1 
ATOM   5957  H  HA   . TYR   B 1 84  ? 23.568  39.478  31.749  1.00 30.46 ? 83  TYR   B HA   1 
ATOM   5958  H  HB2  . TYR   B 1 84  ? 24.874  40.193  33.438  1.00 33.21 ? 83  TYR   B HB2  1 
ATOM   5959  H  HB3  . TYR   B 1 84  ? 24.697  41.715  33.017  1.00 33.21 ? 83  TYR   B HB3  1 
ATOM   5960  H  HD1  . TYR   B 1 84  ? 21.995  39.516  33.603  1.00 27.70 ? 83  TYR   B HD1  1 
ATOM   5961  H  HD2  . TYR   B 1 84  ? 24.035  42.603  35.097  1.00 32.67 ? 83  TYR   B HD2  1 
ATOM   5962  H  HE1  . TYR   B 1 84  ? 20.383  39.803  35.225  1.00 31.41 ? 83  TYR   B HE1  1 
ATOM   5963  H  HE2  . TYR   B 1 84  ? 22.399  42.914  36.696  1.00 29.21 ? 83  TYR   B HE2  1 
ATOM   5964  H  HH   . TYR   B 1 84  ? 19.808  40.882  37.122  1.00 40.04 ? 83  TYR   B HH   1 
ATOM   5965  N  N    . MET   B 1 85  ? 22.737  42.393  30.761  1.00 29.58 ? 84  MET   B N    1 
ATOM   5966  C  CA   . MET   B 1 85  ? 21.589  43.128  30.249  1.00 27.33 ? 84  MET   B CA   1 
ATOM   5967  C  C    . MET   B 1 85  ? 21.056  42.491  28.972  1.00 24.97 ? 84  MET   B C    1 
ATOM   5968  O  O    . MET   B 1 85  ? 19.846  42.341  28.812  1.00 24.52 ? 84  MET   B O    1 
ATOM   5969  C  CB   . MET   B 1 85  ? 21.963  44.588  30.016  1.00 26.53 ? 84  MET   B CB   1 
ATOM   5970  C  CG   . MET   B 1 85  ? 22.205  45.393  31.331  1.00 28.33 ? 84  MET   B CG   1 
ATOM   5971  S  SD   . MET   B 1 85  ? 20.685  45.634  32.271  1.00 31.39 ? 84  MET   B SD   1 
ATOM   5972  C  CE   . MET   B 1 85  ? 20.925  44.518  33.682  1.00 31.53 ? 84  MET   B CE   1 
ATOM   5973  H  H    . MET   B 1 85  ? 23.479  42.827  30.765  1.00 35.50 ? 84  MET   B H    1 
ATOM   5974  H  HA   . MET   B 1 85  ? 20.886  43.112  30.917  1.00 32.80 ? 84  MET   B HA   1 
ATOM   5975  H  HB2  . MET   B 1 85  ? 22.780  44.621  29.494  1.00 31.83 ? 84  MET   B HB2  1 
ATOM   5976  H  HB3  . MET   B 1 85  ? 21.243  45.021  29.532  1.00 31.83 ? 84  MET   B HB3  1 
ATOM   5977  H  HG2  . MET   B 1 85  ? 22.832  44.908  31.890  1.00 34.00 ? 84  MET   B HG2  1 
ATOM   5978  H  HG3  . MET   B 1 85  ? 22.565  46.266  31.109  1.00 34.00 ? 84  MET   B HG3  1 
ATOM   5979  H  HE1  . MET   B 1 85  ? 20.142  44.558  34.253  1.00 37.84 ? 84  MET   B HE1  1 
ATOM   5980  H  HE2  . MET   B 1 85  ? 21.049  43.614  33.352  1.00 37.84 ? 84  MET   B HE2  1 
ATOM   5981  H  HE3  . MET   B 1 85  ? 21.710  44.800  34.177  1.00 37.84 ? 84  MET   B HE3  1 
ATOM   5982  N  N    . SER   B 1 86  ? 21.953  42.082  28.076  1.00 25.90 ? 85  SER   B N    1 
ATOM   5983  C  CA   . SER   B 1 86  ? 21.516  41.430  26.842  1.00 27.76 ? 85  SER   B CA   1 
ATOM   5984  C  C    . SER   B 1 86  ? 20.684  40.189  27.143  1.00 29.73 ? 85  SER   B C    1 
ATOM   5985  O  O    . SER   B 1 86  ? 19.639  39.967  26.515  1.00 28.67 ? 85  SER   B O    1 
ATOM   5986  C  CB   . SER   B 1 86  ? 22.734  41.044  26.005  1.00 34.20 ? 85  SER   B CB   1 
ATOM   5987  O  OG   . SER   B 1 86  ? 23.445  42.190  25.602  1.00 45.44 ? 85  SER   B OG   1 
ATOM   5988  H  H    . SER   B 1 86  ? 22.805  42.168  28.155  1.00 31.08 ? 85  SER   B H    1 
ATOM   5989  H  HA   . SER   B 1 86  ? 20.971  42.051  26.334  1.00 33.31 ? 85  SER   B HA   1 
ATOM   5990  H  HB2  . SER   B 1 86  ? 23.318  40.482  26.538  1.00 41.04 ? 85  SER   B HB2  1 
ATOM   5991  H  HB3  . SER   B 1 86  ? 22.437  40.563  25.217  1.00 41.04 ? 85  SER   B HB3  1 
ATOM   5992  H  HG   . SER   B 1 86  ? 23.901  42.486  26.243  1.00 54.52 ? 85  SER   B HG   1 
ATOM   5993  N  N    . ALA   B 1 87  ? 21.138  39.366  28.103  1.00 24.57 ? 86  ALA   B N    1 
ATOM   5994  C  CA   . ALA   B 1 87  ? 20.391  38.172  28.485  1.00 22.84 ? 86  ALA   B CA   1 
ATOM   5995  C  C    . ALA   B 1 87  ? 19.048  38.525  29.103  1.00 23.89 ? 86  ALA   B C    1 
ATOM   5996  O  O    . ALA   B 1 87  ? 18.021  37.928  28.761  1.00 22.02 ? 86  ALA   B O    1 
ATOM   5997  C  CB   . ALA   B 1 87  ? 21.206  37.334  29.461  1.00 21.29 ? 86  ALA   B CB   1 
ATOM   5998  H  H    . ALA   B 1 87  ? 21.869  39.481  28.540  1.00 29.49 ? 86  ALA   B H    1 
ATOM   5999  H  HA   . ALA   B 1 87  ? 20.230  37.650  27.684  1.00 27.41 ? 86  ALA   B HA   1 
ATOM   6000  H  HB1  . ALA   B 1 87  ? 20.634  36.651  29.844  1.00 25.55 ? 86  ALA   B HB1  1 
ATOM   6001  H  HB2  . ALA   B 1 87  ? 21.942  36.921  28.984  1.00 25.55 ? 86  ALA   B HB2  1 
ATOM   6002  H  HB3  . ALA   B 1 87  ? 21.548  37.910  30.163  1.00 25.55 ? 86  ALA   B HB3  1 
ATOM   6003  N  N    . LEU   B 1 88  ? 19.036  39.499  30.024  1.00 23.01 ? 87  LEU   B N    1 
ATOM   6004  C  CA   . LEU   B 1 88  ? 17.808  39.832  30.727  1.00 21.58 ? 87  LEU   B CA   1 
ATOM   6005  C  C    . LEU   B 1 88  ? 16.733  40.291  29.769  1.00 24.38 ? 87  LEU   B C    1 
ATOM   6006  O  O    . LEU   B 1 88  ? 15.548  40.044  29.995  1.00 26.11 ? 87  LEU   B O    1 
ATOM   6007  C  CB   . LEU   B 1 88  ? 18.064  40.923  31.757  1.00 27.13 ? 87  LEU   B CB   1 
ATOM   6008  C  CG   . LEU   B 1 88  ? 16.930  41.282  32.711  1.00 29.88 ? 87  LEU   B CG   1 
ATOM   6009  C  CD1  . LEU   B 1 88  ? 16.573  40.168  33.628  1.00 29.46 ? 87  LEU   B CD1  1 
ATOM   6010  C  CD2  . LEU   B 1 88  ? 17.431  42.555  33.433  1.00 32.45 ? 87  LEU   B CD2  1 
ATOM   6011  H  H    . LEU   B 1 88  ? 19.718  39.970  30.252  1.00 27.61 ? 87  LEU   B H    1 
ATOM   6012  H  HA   . LEU   B 1 88  ? 17.500  39.036  31.188  1.00 25.90 ? 87  LEU   B HA   1 
ATOM   6013  H  HB2  . LEU   B 1 88  ? 18.812  40.641  32.307  1.00 32.55 ? 87  LEU   B HB2  1 
ATOM   6014  H  HB3  . LEU   B 1 88  ? 18.293  41.734  31.277  1.00 32.55 ? 87  LEU   B HB3  1 
ATOM   6015  H  HG   . LEU   B 1 88  ? 16.089  41.449  32.256  1.00 35.86 ? 87  LEU   B HG   1 
ATOM   6016  H  HD11 . LEU   B 1 88  ? 16.152  40.534  34.421  1.00 35.35 ? 87  LEU   B HD11 1 
ATOM   6017  H  HD12 . LEU   B 1 88  ? 15.958  39.570  33.174  1.00 35.35 ? 87  LEU   B HD12 1 
ATOM   6018  H  HD13 . LEU   B 1 88  ? 17.380  39.689  33.872  1.00 35.35 ? 87  LEU   B HD13 1 
ATOM   6019  H  HD21 . LEU   B 1 88  ? 16.754  42.848  34.063  1.00 38.94 ? 87  LEU   B HD21 1 
ATOM   6020  H  HD22 . LEU   B 1 88  ? 18.254  42.348  33.904  1.00 38.94 ? 87  LEU   B HD22 1 
ATOM   6021  H  HD23 . LEU   B 1 88  ? 17.593  43.249  32.775  1.00 38.94 ? 87  LEU   B HD23 1 
ATOM   6022  N  N    . ASN   B 1 89  ? 17.123  41.014  28.723  1.00 26.56 ? 88  ASN   B N    1 
ATOM   6023  C  CA   . ASN   B 1 89  ? 16.146  41.468  27.738  1.00 27.43 ? 88  ASN   B CA   1 
ATOM   6024  C  C    . ASN   B 1 89  ? 15.352  40.299  27.158  1.00 29.74 ? 88  ASN   B C    1 
ATOM   6025  O  O    . ASN   B 1 89  ? 14.185  40.464  26.787  1.00 29.43 ? 88  ASN   B O    1 
ATOM   6026  C  CB   . ASN   B 1 89  ? 16.873  42.248  26.639  1.00 29.74 ? 88  ASN   B CB   1 
ATOM   6027  C  CG   . ASN   B 1 89  ? 15.953  43.191  25.882  1.00 33.10 ? 88  ASN   B CG   1 
ATOM   6028  O  OD1  . ASN   B 1 89  ? 15.136  43.896  26.475  1.00 33.63 ? 88  ASN   B OD1  1 
ATOM   6029  N  ND2  . ASN   B 1 89  ? 16.106  43.223  24.566  1.00 39.74 ? 88  ASN   B ND2  1 
ATOM   6030  H  H    . ASN   B 1 89  ? 17.934  41.252  28.562  1.00 31.87 ? 88  ASN   B H    1 
ATOM   6031  H  HA   . ASN   B 1 89  ? 15.506  42.064  28.156  1.00 32.91 ? 88  ASN   B HA   1 
ATOM   6032  H  HB2  . ASN   B 1 89  ? 17.579  42.777  27.042  1.00 35.69 ? 88  ASN   B HB2  1 
ATOM   6033  H  HB3  . ASN   B 1 89  ? 17.250  41.621  26.002  1.00 35.69 ? 88  ASN   B HB3  1 
ATOM   6034  H  HD21 . ASN   B 1 89  ? 16.700  42.729  24.190  1.00 47.69 ? 88  ASN   B HD21 1 
ATOM   6035  H  HD22 . ASN   B 1 89  ? 15.611  43.740  24.089  1.00 47.69 ? 88  ASN   B HD22 1 
ATOM   6036  N  N    . HIS   B 1 90  ? 15.946  39.104  27.113  1.00 26.95 ? 89  HIS   B N    1 
ATOM   6037  C  CA   . HIS   B 1 90  ? 15.240  37.886  26.713  1.00 25.85 ? 89  HIS   B CA   1 
ATOM   6038  C  C    . HIS   B 1 90  ? 14.592  37.144  27.868  1.00 25.07 ? 89  HIS   B C    1 
ATOM   6039  O  O    . HIS   B 1 90  ? 13.447  36.696  27.752  1.00 26.59 ? 89  HIS   B O    1 
ATOM   6040  C  CB   . HIS   B 1 90  ? 16.200  36.902  26.025  1.00 28.54 ? 89  HIS   B CB   1 
ATOM   6041  C  CG   . HIS   B 1 90  ? 16.680  37.360  24.693  1.00 28.83 ? 89  HIS   B CG   1 
ATOM   6042  N  ND1  . HIS   B 1 90  ? 17.926  37.921  24.498  1.00 32.63 ? 89  HIS   B ND1  1 
ATOM   6043  C  CD2  . HIS   B 1 90  ? 16.101  37.289  23.474  1.00 30.66 ? 89  HIS   B CD2  1 
ATOM   6044  C  CE1  . HIS   B 1 90  ? 18.072  38.219  23.218  1.00 30.72 ? 89  HIS   B CE1  1 
ATOM   6045  N  NE2  . HIS   B 1 90  ? 16.978  37.847  22.578  1.00 37.81 ? 89  HIS   B NE2  1 
ATOM   6046  H  H    . HIS   B 1 90  ? 16.771  38.971  27.312  1.00 32.34 ? 89  HIS   B H    1 
ATOM   6047  H  HA   . HIS   B 1 90  ? 14.549  38.171  26.094  1.00 31.02 ? 89  HIS   B HA   1 
ATOM   6048  H  HB2  . HIS   B 1 90  ? 16.977  36.778  26.592  1.00 34.25 ? 89  HIS   B HB2  1 
ATOM   6049  H  HB3  . HIS   B 1 90  ? 15.742  36.057  25.900  1.00 34.25 ? 89  HIS   B HB3  1 
ATOM   6050  H  HD1  . HIS   B 1 90  ? 18.514  38.054  25.111  1.00 39.16 ? 89  HIS   B HD1  1 
ATOM   6051  H  HD2  . HIS   B 1 90  ? 15.265  36.930  23.279  1.00 36.79 ? 89  HIS   B HD2  1 
ATOM   6052  H  HE1  . HIS   B 1 90  ? 18.817  38.622  22.834  1.00 36.87 ? 89  HIS   B HE1  1 
ATOM   6053  N  N    . THR   B 1 91  ? 15.334  36.932  28.967  1.00 22.99 ? 90  THR   B N    1 
ATOM   6054  C  CA   . THR   B 1 91  ? 14.774  36.113  30.037  1.00 25.16 ? 90  THR   B CA   1 
ATOM   6055  C  C    . THR   B 1 91  ? 13.571  36.775  30.708  1.00 25.17 ? 90  THR   B C    1 
ATOM   6056  O  O    . THR   B 1 91  ? 12.768  36.072  31.320  1.00 23.93 ? 90  THR   B O    1 
ATOM   6057  C  CB   . THR   B 1 91  ? 15.807  35.787  31.121  1.00 24.91 ? 90  THR   B CB   1 
ATOM   6058  O  OG1  . THR   B 1 91  ? 16.194  36.984  31.820  1.00 24.55 ? 90  THR   B OG1  1 
ATOM   6059  C  CG2  . THR   B 1 91  ? 17.025  35.101  30.530  1.00 24.59 ? 90  THR   B CG2  1 
ATOM   6060  H  H    . THR   B 1 91  ? 16.125  37.239  29.105  1.00 27.58 ? 90  THR   B H    1 
ATOM   6061  H  HA   . THR   B 1 91  ? 14.503  35.276  29.629  1.00 30.20 ? 90  THR   B HA   1 
ATOM   6062  H  HB   . THR   B 1 91  ? 15.409  35.174  31.759  1.00 29.89 ? 90  THR   B HB   1 
ATOM   6063  H  HG1  . THR   B 1 91  ? 16.737  36.796  32.433  1.00 29.46 ? 90  THR   B HG1  1 
ATOM   6064  H  HG21 . THR   B 1 91  ? 17.264  34.329  31.067  1.00 29.51 ? 90  THR   B HG21 1 
ATOM   6065  H  HG22 . THR   B 1 91  ? 16.835  34.808  29.625  1.00 29.51 ? 90  THR   B HG22 1 
ATOM   6066  H  HG23 . THR   B 1 91  ? 17.775  35.715  30.511  1.00 29.51 ? 90  THR   B HG23 1 
ATOM   6067  N  N    . LYS   B 1 92  ? 13.451  38.106  30.651  1.00 25.08 ? 91  LYS   B N    1 
ATOM   6068  C  CA   . LYS   B 1 92  ? 12.259  38.740  31.217  1.00 24.09 ? 91  LYS   B CA   1 
ATOM   6069  C  C    . LYS   B 1 92  ? 10.998  38.366  30.453  1.00 30.41 ? 91  LYS   B C    1 
ATOM   6070  O  O    . LYS   B 1 92  ? 9.898   38.534  30.986  1.00 27.25 ? 91  LYS   B O    1 
ATOM   6071  C  CB   . LYS   B 1 92  ? 12.396  40.258  31.249  1.00 25.97 ? 91  LYS   B CB   1 
ATOM   6072  C  CG   . LYS   B 1 92  ? 12.363  40.899  29.867  1.00 31.33 ? 91  LYS   B CG   1 
ATOM   6073  C  CD   . LYS   B 1 92  ? 12.884  42.324  29.894  1.00 35.57 ? 91  LYS   B CD   1 
ATOM   6074  C  CE   . LYS   B 1 92  ? 12.456  43.062  28.645  1.00 37.01 ? 91  LYS   B CE   1 
ATOM   6075  N  NZ   . LYS   B 1 92  ? 12.781  44.503  28.722  1.00 40.52 ? 91  LYS   B NZ   1 
ATOM   6076  H  H    . LYS   B 1 92  ? 14.025  38.644  30.303  1.00 30.09 ? 91  LYS   B H    1 
ATOM   6077  H  HA   . LYS   B 1 92  ? 12.172  38.439  32.135  1.00 28.91 ? 91  LYS   B HA   1 
ATOM   6078  H  HB2  . LYS   B 1 92  ? 11.664  40.628  31.766  1.00 31.16 ? 91  LYS   B HB2  1 
ATOM   6079  H  HB3  . LYS   B 1 92  ? 13.243  40.487  31.663  1.00 31.16 ? 91  LYS   B HB3  1 
ATOM   6080  H  HG2  . LYS   B 1 92  ? 12.920  40.384  29.262  1.00 37.59 ? 91  LYS   B HG2  1 
ATOM   6081  H  HG3  . LYS   B 1 92  ? 11.449  40.916  29.544  1.00 37.59 ? 91  LYS   B HG3  1 
ATOM   6082  H  HD2  . LYS   B 1 92  ? 12.525  42.788  30.667  1.00 42.68 ? 91  LYS   B HD2  1 
ATOM   6083  H  HD3  . LYS   B 1 92  ? 13.854  42.317  29.932  1.00 42.68 ? 91  LYS   B HD3  1 
ATOM   6084  H  HE2  . LYS   B 1 92  ? 12.915  42.687  27.877  1.00 44.41 ? 91  LYS   B HE2  1 
ATOM   6085  H  HE3  . LYS   B 1 92  ? 11.496  42.973  28.533  1.00 44.41 ? 91  LYS   B HE3  1 
ATOM   6086  H  HZ1  . LYS   B 1 92  ? 12.365  44.944  28.071  1.00 48.63 ? 91  LYS   B HZ1  1 
ATOM   6087  H  HZ2  . LYS   B 1 92  ? 12.520  44.832  29.507  1.00 48.63 ? 91  LYS   B HZ2  1 
ATOM   6088  H  HZ3  . LYS   B 1 92  ? 13.659  44.621  28.637  1.00 48.63 ? 91  LYS   B HZ3  1 
ATOM   6089  N  N    . LYS   B 1 93  ? 11.127  37.868  29.213  1.00 22.76 ? 92  LYS   B N    1 
ATOM   6090  C  CA   . LYS   B 1 93  ? 9.972   37.435  28.432  1.00 28.63 ? 92  LYS   B CA   1 
ATOM   6091  C  C    . LYS   B 1 93  ? 9.686   35.947  28.555  1.00 28.13 ? 92  LYS   B C    1 
ATOM   6092  O  O    . LYS   B 1 93  ? 8.620   35.493  28.121  1.00 27.12 ? 92  LYS   B O    1 
ATOM   6093  C  CB   . LYS   B 1 93  ? 10.169  37.774  26.959  1.00 29.53 ? 92  LYS   B CB   1 
ATOM   6094  C  CG   . LYS   B 1 93  ? 10.775  39.139  26.686  1.00 38.47 ? 92  LYS   B CG   1 
ATOM   6095  C  CD   . LYS   B 1 93  ? 10.003  39.892  25.625  1.00 49.75 ? 92  LYS   B CD   1 
ATOM   6096  C  CE   . LYS   B 1 93  ? 10.472  41.337  25.524  1.00 48.77 ? 92  LYS   B CE   1 
ATOM   6097  N  NZ   . LYS   B 1 93  ? 11.776  41.422  24.805  1.00 55.47 ? 92  LYS   B NZ   1 
ATOM   6098  H  H    . LYS   B 1 93  ? 11.878  37.772  28.806  1.00 27.31 ? 92  LYS   B H    1 
ATOM   6099  H  HA   . LYS   B 1 93  ? 9.196   37.919  28.755  1.00 34.35 ? 92  LYS   B HA   1 
ATOM   6100  H  HB2  . LYS   B 1 93  ? 10.759  37.111  26.568  1.00 35.44 ? 92  LYS   B HB2  1 
ATOM   6101  H  HB3  . LYS   B 1 93  ? 9.304   37.748  26.521  1.00 35.44 ? 92  LYS   B HB3  1 
ATOM   6102  H  HG2  . LYS   B 1 93  ? 10.762  39.664  27.502  1.00 46.16 ? 92  LYS   B HG2  1 
ATOM   6103  H  HG3  . LYS   B 1 93  ? 11.687  39.028  26.377  1.00 46.16 ? 92  LYS   B HG3  1 
ATOM   6104  H  HD2  . LYS   B 1 93  ? 10.138  39.466  24.765  1.00 59.70 ? 92  LYS   B HD2  1 
ATOM   6105  H  HD3  . LYS   B 1 93  ? 9.060   39.891  25.851  1.00 59.70 ? 92  LYS   B HD3  1 
ATOM   6106  H  HE2  . LYS   B 1 93  ? 9.816   41.857  25.035  1.00 58.52 ? 92  LYS   B HE2  1 
ATOM   6107  H  HE3  . LYS   B 1 93  ? 10.588  41.703  26.415  1.00 58.52 ? 92  LYS   B HE3  1 
ATOM   6108  H  HZ1  . LYS   B 1 93  ? 11.912  42.254  24.519  1.00 66.57 ? 92  LYS   B HZ1  1 
ATOM   6109  H  HZ2  . LYS   B 1 93  ? 12.440  41.191  25.350  1.00 66.57 ? 92  LYS   B HZ2  1 
ATOM   6110  H  HZ3  . LYS   B 1 93  ? 11.773  40.874  24.104  1.00 66.57 ? 92  LYS   B HZ3  1 
ATOM   6111  N  N    . TRP   B 1 94  ? 10.596  35.179  29.141  1.00 22.84 ? 93  TRP   B N    1 
ATOM   6112  C  CA   . TRP   B 1 94  ? 10.296  33.804  29.460  1.00 22.10 ? 93  TRP   B CA   1 
ATOM   6113  C  C    . TRP   B 1 94  ? 9.167   33.738  30.489  1.00 27.61 ? 93  TRP   B C    1 
ATOM   6114  O  O    . TRP   B 1 94  ? 8.847   34.712  31.188  1.00 27.58 ? 93  TRP   B O    1 
ATOM   6115  C  CB   . TRP   B 1 94  ? 11.555  33.098  29.990  1.00 22.52 ? 93  TRP   B CB   1 
ATOM   6116  C  CG   . TRP   B 1 94  ? 12.665  32.926  28.983  1.00 21.51 ? 93  TRP   B CG   1 
ATOM   6117  C  CD1  . TRP   B 1 94  ? 12.613  33.206  27.631  1.00 22.72 ? 93  TRP   B CD1  1 
ATOM   6118  C  CD2  . TRP   B 1 94  ? 13.979  32.422  29.234  1.00 22.39 ? 93  TRP   B CD2  1 
ATOM   6119  N  NE1  . TRP   B 1 94  ? 13.837  32.929  27.049  1.00 22.59 ? 93  TRP   B NE1  1 
ATOM   6120  C  CE2  . TRP   B 1 94  ? 14.681  32.428  28.007  1.00 20.91 ? 93  TRP   B CE2  1 
ATOM   6121  C  CE3  . TRP   B 1 94  ? 14.642  31.965  30.386  1.00 24.81 ? 93  TRP   B CE3  1 
ATOM   6122  C  CZ2  . TRP   B 1 94  ? 16.014  32.002  27.899  1.00 18.62 ? 93  TRP   B CZ2  1 
ATOM   6123  C  CZ3  . TRP   B 1 94  ? 15.952  31.553  30.276  1.00 21.03 ? 93  TRP   B CZ3  1 
ATOM   6124  C  CH2  . TRP   B 1 94  ? 16.622  31.550  29.028  1.00 20.83 ? 93  TRP   B CH2  1 
ATOM   6125  H  H    . TRP   B 1 94  ? 11.388  35.433  29.360  1.00 27.40 ? 93  TRP   B H    1 
ATOM   6126  H  HA   . TRP   B 1 94  ? 10.004  33.332  28.664  1.00 26.53 ? 93  TRP   B HA   1 
ATOM   6127  H  HB2  . TRP   B 1 94  ? 11.911  33.618  30.728  1.00 27.03 ? 93  TRP   B HB2  1 
ATOM   6128  H  HB3  . TRP   B 1 94  ? 11.304  32.213  30.299  1.00 27.03 ? 93  TRP   B HB3  1 
ATOM   6129  H  HD1  . TRP   B 1 94  ? 11.868  33.531  27.181  1.00 27.26 ? 93  TRP   B HD1  1 
ATOM   6130  H  HE1  . TRP   B 1 94  ? 14.037  33.051  26.221  1.00 27.11 ? 93  TRP   B HE1  1 
ATOM   6131  H  HE3  . TRP   B 1 94  ? 14.205  31.940  31.206  1.00 29.77 ? 93  TRP   B HE3  1 
ATOM   6132  H  HZ2  . TRP   B 1 94  ? 16.464  32.028  27.086  1.00 22.34 ? 93  TRP   B HZ2  1 
ATOM   6133  H  HZ3  . TRP   B 1 94  ? 16.406  31.271  31.037  1.00 25.24 ? 93  TRP   B HZ3  1 
ATOM   6134  H  HH2  . TRP   B 1 94  ? 17.494  31.232  28.980  1.00 24.99 ? 93  TRP   B HH2  1 
ATOM   6135  N  N    . LYS   B 1 95  ? 8.557   32.576  30.568  1.00 23.10 ? 94  LYS   B N    1 
ATOM   6136  C  CA   . LYS   B 1 95  ? 7.572   32.272  31.588  1.00 26.11 ? 94  LYS   B CA   1 
ATOM   6137  C  C    . LYS   B 1 95  ? 8.163   31.346  32.640  1.00 28.20 ? 94  LYS   B C    1 
ATOM   6138  O  O    . LYS   B 1 95  ? 8.867   30.379  32.322  1.00 22.37 ? 94  LYS   B O    1 
ATOM   6139  C  CB   . LYS   B 1 95  ? 6.339   31.593  30.999  1.00 29.82 ? 94  LYS   B CB   1 
ATOM   6140  C  CG   . LYS   B 1 95  ? 5.526   32.415  30.044  1.00 37.21 ? 94  LYS   B CG   1 
ATOM   6141  C  CD   . LYS   B 1 95  ? 5.034   33.693  30.684  1.00 40.56 ? 94  LYS   B CD   1 
ATOM   6142  C  CE   . LYS   B 1 95  ? 4.563   34.673  29.616  1.00 45.02 ? 94  LYS   B CE   1 
ATOM   6143  N  NZ   . LYS   B 1 95  ? 5.631   35.667  29.279  1.00 56.31 ? 94  LYS   B NZ   1 
ATOM   6144  H  H    . LYS   B 1 95  ? 8.699   31.925  30.025  1.00 27.72 ? 94  LYS   B H    1 
ATOM   6145  H  HA   . LYS   B 1 95  ? 7.306   33.107  32.003  1.00 31.33 ? 94  LYS   B HA   1 
ATOM   6146  H  HB2  . LYS   B 1 95  ? 6.629   30.801  30.520  1.00 35.79 ? 94  LYS   B HB2  1 
ATOM   6147  H  HB3  . LYS   B 1 95  ? 5.753   31.342  31.731  1.00 35.79 ? 94  LYS   B HB3  1 
ATOM   6148  H  HG2  . LYS   B 1 95  ? 6.073   32.650  29.278  1.00 44.65 ? 94  LYS   B HG2  1 
ATOM   6149  H  HG3  . LYS   B 1 95  ? 4.755   31.903  29.756  1.00 44.65 ? 94  LYS   B HG3  1 
ATOM   6150  H  HD2  . LYS   B 1 95  ? 4.290   33.496  31.274  1.00 48.68 ? 94  LYS   B HD2  1 
ATOM   6151  H  HD3  . LYS   B 1 95  ? 5.755   34.105  31.186  1.00 48.68 ? 94  LYS   B HD3  1 
ATOM   6152  H  HE2  . LYS   B 1 95  ? 4.334   34.185  28.810  1.00 54.03 ? 94  LYS   B HE2  1 
ATOM   6153  H  HE3  . LYS   B 1 95  ? 3.788   35.157  29.943  1.00 54.03 ? 94  LYS   B HE3  1 
ATOM   6154  H  HZ1  . LYS   B 1 95  ? 5.263   36.416  28.972  1.00 67.57 ? 94  LYS   B HZ1  1 
ATOM   6155  H  HZ2  . LYS   B 1 95  ? 6.110   35.856  30.005  1.00 67.57 ? 94  LYS   B HZ2  1 
ATOM   6156  H  HZ3  . LYS   B 1 95  ? 6.171   35.333  28.656  1.00 67.57 ? 94  LYS   B HZ3  1 
ATOM   6157  N  N    . TYR   B 1 96  ? 7.785   31.583  33.898  1.00 25.18 ? 95  TYR   B N    1 
ATOM   6158  C  CA   . TYR   B 1 96  ? 8.316   30.833  35.030  1.00 25.58 ? 95  TYR   B CA   1 
ATOM   6159  C  C    . TYR   B 1 96  ? 7.176   30.195  35.814  1.00 30.84 ? 95  TYR   B C    1 
ATOM   6160  O  O    . TYR   B 1 96  ? 6.853   30.621  36.935  1.00 29.03 ? 95  TYR   B O    1 
ATOM   6161  C  CB   . TYR   B 1 96  ? 9.142   31.767  35.903  1.00 24.45 ? 95  TYR   B CB   1 
ATOM   6162  C  CG   . TYR   B 1 96  ? 10.291  32.360  35.146  1.00 23.03 ? 95  TYR   B CG   1 
ATOM   6163  C  CD1  . TYR   B 1 96  ? 11.465  31.649  34.963  1.00 24.20 ? 95  TYR   B CD1  1 
ATOM   6164  C  CD2  . TYR   B 1 96  ? 10.176  33.605  34.551  1.00 24.04 ? 95  TYR   B CD2  1 
ATOM   6165  C  CE1  . TYR   B 1 96  ? 12.510  32.188  34.251  1.00 21.27 ? 95  TYR   B CE1  1 
ATOM   6166  C  CE2  . TYR   B 1 96  ? 11.214  34.158  33.836  1.00 23.45 ? 95  TYR   B CE2  1 
ATOM   6167  C  CZ   . TYR   B 1 96  ? 12.377  33.455  33.687  1.00 21.18 ? 95  TYR   B CZ   1 
ATOM   6168  O  OH   . TYR   B 1 96  ? 13.386  34.002  32.942  1.00 24.90 ? 95  TYR   B OH   1 
ATOM   6169  H  H    . TYR   B 1 96  ? 7.211   32.184  34.120  1.00 30.22 ? 95  TYR   B H    1 
ATOM   6170  H  HA   . TYR   B 1 96  ? 8.872   30.103  34.716  1.00 30.69 ? 95  TYR   B HA   1 
ATOM   6171  H  HB2  . TYR   B 1 96  ? 8.579   32.491  36.219  1.00 29.33 ? 95  TYR   B HB2  1 
ATOM   6172  H  HB3  . TYR   B 1 96  ? 9.497   31.271  36.657  1.00 29.33 ? 95  TYR   B HB3  1 
ATOM   6173  H  HD1  . TYR   B 1 96  ? 11.548  30.798  35.327  1.00 29.04 ? 95  TYR   B HD1  1 
ATOM   6174  H  HD2  . TYR   B 1 96  ? 9.380   34.078  34.636  1.00 28.85 ? 95  TYR   B HD2  1 
ATOM   6175  H  HE1  . TYR   B 1 96  ? 13.300  31.710  34.146  1.00 25.53 ? 95  TYR   B HE1  1 
ATOM   6176  H  HE2  . TYR   B 1 96  ? 11.125  35.003  33.458  1.00 28.14 ? 95  TYR   B HE2  1 
ATOM   6177  H  HH   . TYR   B 1 96  ? 13.225  34.812  32.789  1.00 29.87 ? 95  TYR   B HH   1 
ATOM   6178  N  N    . PRO   B 1 97  ? 6.586   29.136  35.276  1.00 27.79 ? 96  PRO   B N    1 
ATOM   6179  C  CA   . PRO   B 1 97  ? 5.476   28.487  35.975  1.00 31.76 ? 96  PRO   B CA   1 
ATOM   6180  C  C    . PRO   B 1 97  ? 5.956   27.812  37.246  1.00 33.75 ? 96  PRO   B C    1 
ATOM   6181  O  O    . PRO   B 1 97  ? 7.063   27.261  37.317  1.00 27.12 ? 96  PRO   B O    1 
ATOM   6182  C  CB   . PRO   B 1 97  ? 4.969   27.453  34.963  1.00 33.73 ? 96  PRO   B CB   1 
ATOM   6183  C  CG   . PRO   B 1 97  ? 6.216   27.141  34.107  1.00 27.66 ? 96  PRO   B CG   1 
ATOM   6184  C  CD   . PRO   B 1 97  ? 6.916   28.466  33.992  1.00 26.19 ? 96  PRO   B CD   1 
ATOM   6185  H  HA   . PRO   B 1 97  ? 4.770   29.122  36.176  1.00 38.11 ? 96  PRO   B HA   1 
ATOM   6186  H  HB2  . PRO   B 1 97  ? 4.651   26.661  35.424  1.00 40.47 ? 96  PRO   B HB2  1 
ATOM   6187  H  HB3  . PRO   B 1 97  ? 4.257   27.832  34.424  1.00 40.47 ? 96  PRO   B HB3  1 
ATOM   6188  H  HG2  . PRO   B 1 97  ? 6.775   26.487  34.555  1.00 33.19 ? 96  PRO   B HG2  1 
ATOM   6189  H  HG3  . PRO   B 1 97  ? 5.949   26.808  33.236  1.00 33.19 ? 96  PRO   B HG3  1 
ATOM   6190  H  HD2  . PRO   B 1 97  ? 7.874   28.344  33.902  1.00 31.42 ? 96  PRO   B HD2  1 
ATOM   6191  H  HD3  . PRO   B 1 97  ? 6.574   28.974  33.239  1.00 31.42 ? 96  PRO   B HD3  1 
ATOM   6192  N  N    . GLN   B 1 98  ? 5.093   27.842  38.257  1.00 30.14 ? 97  GLN   B N    1 
ATOM   6193  C  CA   . GLN   B 1 98  ? 5.315   27.019  39.426  1.00 29.92 ? 97  GLN   B CA   1 
ATOM   6194  C  C    . GLN   B 1 98  ? 4.913   25.624  39.010  1.00 30.98 ? 97  GLN   B C    1 
ATOM   6195  O  O    . GLN   B 1 98  ? 3.792   25.391  38.543  1.00 34.54 ? 97  GLN   B O    1 
ATOM   6196  C  CB   . GLN   B 1 98  ? 4.485   27.528  40.608  1.00 28.34 ? 97  GLN   B CB   1 
ATOM   6197  C  CG   . GLN   B 1 98  ? 4.988   28.836  41.153  1.00 33.85 ? 97  GLN   B CG   1 
ATOM   6198  C  CD   . GLN   B 1 98  ? 6.359   28.732  41.797  1.00 36.92 ? 97  GLN   B CD   1 
ATOM   6199  O  OE1  . GLN   B 1 98  ? 6.596   27.898  42.674  1.00 39.04 ? 97  GLN   B OE1  1 
ATOM   6200  N  NE2  . GLN   B 1 98  ? 7.273   29.584  41.363  1.00 34.05 ? 97  GLN   B NE2  1 
ATOM   6201  H  H    . GLN   B 1 98  ? 4.383   28.326  38.283  1.00 36.16 ? 97  GLN   B H    1 
ATOM   6202  H  HA   . GLN   B 1 98  ? 6.238   27.035  39.723  1.00 35.91 ? 97  GLN   B HA   1 
ATOM   6203  H  HB2  . GLN   B 1 98  ? 3.568   27.656  40.319  1.00 34.01 ? 97  GLN   B HB2  1 
ATOM   6204  H  HB3  . GLN   B 1 98  ? 4.519   26.872  41.323  1.00 34.01 ? 97  GLN   B HB3  1 
ATOM   6205  H  HG2  . GLN   B 1 98  ? 5.049   29.476  40.426  1.00 40.61 ? 97  GLN   B HG2  1 
ATOM   6206  H  HG3  . GLN   B 1 98  ? 4.367   29.156  41.826  1.00 40.61 ? 97  GLN   B HG3  1 
ATOM   6207  H  HE21 . GLN   B 1 98  ? 7.073   30.154  40.750  1.00 40.86 ? 97  GLN   B HE21 1 
ATOM   6208  H  HE22 . GLN   B 1 98  ? 8.067   29.569  41.693  1.00 40.86 ? 97  GLN   B HE22 1 
ATOM   6209  N  N    . VAL   B 1 99  ? 5.842   24.701  39.113  1.00 32.35 ? 98  VAL   B N    1 
ATOM   6210  C  CA   . VAL   B 1 99  ? 5.593   23.337  38.705  1.00 34.39 ? 98  VAL   B CA   1 
ATOM   6211  C  C    . VAL   B 1 99  ? 6.016   22.467  39.860  1.00 30.62 ? 98  VAL   B C    1 
ATOM   6212  O  O    . VAL   B 1 99  ? 7.194   22.467  40.229  1.00 32.51 ? 98  VAL   B O    1 
ATOM   6213  C  CB   . VAL   B 1 99  ? 6.351   22.952  37.426  1.00 27.56 ? 98  VAL   B CB   1 
ATOM   6214  C  CG1  . VAL   B 1 99  ? 5.958   21.551  37.015  1.00 33.29 ? 98  VAL   B CG1  1 
ATOM   6215  C  CG2  . VAL   B 1 99  ? 6.054   23.961  36.327  1.00 28.95 ? 98  VAL   B CG2  1 
ATOM   6216  H  H    . VAL   B 1 99  ? 6.633   24.841  39.418  1.00 38.82 ? 98  VAL   B H    1 
ATOM   6217  H  HA   . VAL   B 1 99  ? 4.648   23.209  38.529  1.00 41.27 ? 98  VAL   B HA   1 
ATOM   6218  H  HB   . VAL   B 1 99  ? 7.309   22.963  37.583  1.00 33.07 ? 98  VAL   B HB   1 
ATOM   6219  H  HG11 . VAL   B 1 99  ? 6.047   21.467  36.053  1.00 39.95 ? 98  VAL   B HG11 1 
ATOM   6220  H  HG12 . VAL   B 1 99  ? 6.544   20.916  37.457  1.00 39.95 ? 98  VAL   B HG12 1 
ATOM   6221  H  HG13 . VAL   B 1 99  ? 5.038   21.391  37.278  1.00 39.95 ? 98  VAL   B HG13 1 
ATOM   6222  H  HG21 . VAL   B 1 99  ? 6.214   23.545  35.465  1.00 34.74 ? 98  VAL   B HG21 1 
ATOM   6223  H  HG22 . VAL   B 1 99  ? 5.126   24.236  36.394  1.00 34.74 ? 98  VAL   B HG22 1 
ATOM   6224  H  HG23 . VAL   B 1 99  ? 6.636   24.729  36.437  1.00 34.74 ? 98  VAL   B HG23 1 
ATOM   6225  N  N    . ASN   B 1 100 ? 5.066   21.765  40.464  1.00 35.32 ? 99  ASN   B N    1 
ATOM   6226  C  CA   . ASN   B 1 100 ? 5.411   20.855  41.544  1.00 33.24 ? 99  ASN   B CA   1 
ATOM   6227  C  C    . ASN   B 1 100 ? 6.109   21.595  42.683  1.00 37.16 ? 99  ASN   B C    1 
ATOM   6228  O  O    . ASN   B 1 100 ? 7.122   21.130  43.209  1.00 38.23 ? 99  ASN   B O    1 
ATOM   6229  C  CB   . ASN   B 1 100 ? 6.319   19.752  40.994  1.00 36.38 ? 99  ASN   B CB   1 
ATOM   6230  C  CG   . ASN   B 1 100 ? 6.561   18.615  41.971  1.00 39.22 ? 99  ASN   B CG   1 
ATOM   6231  O  OD1  . ASN   B 1 100 ? 5.638   18.102  42.611  1.00 38.60 ? 99  ASN   B OD1  1 
ATOM   6232  N  ND2  . ASN   B 1 100 ? 7.827   18.244  42.122  1.00 31.93 ? 99  ASN   B ND2  1 
ATOM   6233  H  H    . ASN   B 1 100 ? 4.230   21.798  40.268  1.00 42.38 ? 99  ASN   B H    1 
ATOM   6234  H  HA   . ASN   B 1 100 ? 4.603   20.462  41.911  1.00 39.88 ? 99  ASN   B HA   1 
ATOM   6235  H  HB2  . ASN   B 1 100 ? 5.908   19.377  40.199  1.00 43.66 ? 99  ASN   B HB2  1 
ATOM   6236  H  HB3  . ASN   B 1 100 ? 7.180   20.138  40.771  1.00 43.66 ? 99  ASN   B HB3  1 
ATOM   6237  H  HD21 . ASN   B 1 100 ? 8.448   18.642  41.679  1.00 38.31 ? 99  ASN   B HD21 1 
ATOM   6238  H  HD22 . ASN   B 1 100 ? 8.027   17.605  42.662  1.00 38.31 ? 99  ASN   B HD22 1 
ATOM   6239  N  N    . GLY   B 1 101 ? 5.614   22.788  43.019  1.00 36.28 ? 100 GLY   B N    1 
ATOM   6240  C  CA   . GLY   B 1 101 ? 6.126   23.567  44.139  1.00 28.68 ? 100 GLY   B CA   1 
ATOM   6241  C  C    . GLY   B 1 101 ? 7.479   24.218  43.923  1.00 34.73 ? 100 GLY   B C    1 
ATOM   6242  O  O    . GLY   B 1 101 ? 8.017   24.854  44.836  1.00 27.69 ? 100 GLY   B O    1 
ATOM   6243  H  H    . GLY   B 1 101 ? 4.967   23.173  42.604  1.00 43.54 ? 100 GLY   B H    1 
ATOM   6244  H  HA2  . GLY   B 1 101 ? 5.490   24.273  44.338  1.00 34.42 ? 100 GLY   B HA2  1 
ATOM   6245  H  HA3  . GLY   B 1 101 ? 6.202   22.984  44.910  1.00 34.42 ? 100 GLY   B HA3  1 
ATOM   6246  N  N    . LEU   B 1 102 ? 8.019   24.121  42.721  1.00 29.24 ? 101 LEU   B N    1 
ATOM   6247  C  CA   . LEU   B 1 102 ? 9.308   24.679  42.351  1.00 29.46 ? 101 LEU   B CA   1 
ATOM   6248  C  C    . LEU   B 1 102 ? 9.153   25.645  41.192  1.00 27.89 ? 101 LEU   B C    1 
ATOM   6249  O  O    . LEU   B 1 102 ? 8.238   25.507  40.381  1.00 28.37 ? 101 LEU   B O    1 
ATOM   6250  C  CB   . LEU   B 1 102 ? 10.249  23.560  41.971  1.00 27.71 ? 101 LEU   B CB   1 
ATOM   6251  C  CG   . LEU   B 1 102 ? 10.581  22.601  43.098  1.00 28.99 ? 101 LEU   B CG   1 
ATOM   6252  C  CD1  . LEU   B 1 102 ? 10.960  21.298  42.466  1.00 30.05 ? 101 LEU   B CD1  1 
ATOM   6253  C  CD2  . LEU   B 1 102 ? 11.701  23.178  43.962  1.00 29.42 ? 101 LEU   B CD2  1 
ATOM   6254  H  H    . LEU   B 1 102 ? 7.637   23.715  42.067  1.00 35.09 ? 101 LEU   B H    1 
ATOM   6255  H  HA   . LEU   B 1 102 ? 9.684   25.181  43.090  1.00 35.35 ? 101 LEU   B HA   1 
ATOM   6256  H  HB2  . LEU   B 1 102 ? 9.841   23.044  41.258  1.00 33.25 ? 101 LEU   B HB2  1 
ATOM   6257  H  HB3  . LEU   B 1 102 ? 11.082  23.951  41.664  1.00 33.25 ? 101 LEU   B HB3  1 
ATOM   6258  H  HG   . LEU   B 1 102 ? 9.830   22.458  43.695  1.00 34.79 ? 101 LEU   B HG   1 
ATOM   6259  H  HD11 . LEU   B 1 102 ? 11.378  20.733  43.134  1.00 36.07 ? 101 LEU   B HD11 1 
ATOM   6260  H  HD12 . LEU   B 1 102 ? 10.160  20.869  42.123  1.00 36.07 ? 101 LEU   B HD12 1 
ATOM   6261  H  HD13 . LEU   B 1 102 ? 11.581  21.467  41.741  1.00 36.07 ? 101 LEU   B HD13 1 
ATOM   6262  H  HD21 . LEU   B 1 102 ? 11.996  22.500  44.590  1.00 35.30 ? 101 LEU   B HD21 1 
ATOM   6263  H  HD22 . LEU   B 1 102 ? 12.438  23.441  43.389  1.00 35.30 ? 101 LEU   B HD22 1 
ATOM   6264  H  HD23 . LEU   B 1 102 ? 11.364  23.950  44.442  1.00 35.30 ? 101 LEU   B HD23 1 
ATOM   6265  N  N    . THR   B 1 103 ? 10.019  26.648  41.130  1.00 24.14 ? 102 THR   B N    1 
ATOM   6266  C  CA   . THR   B 1 103 ? 10.013  27.535  39.967  1.00 22.70 ? 102 THR   B CA   1 
ATOM   6267  C  C    . THR   B 1 103 ? 10.712  26.837  38.797  1.00 23.53 ? 102 THR   B C    1 
ATOM   6268  O  O    . THR   B 1 103 ? 11.876  26.428  38.900  1.00 20.49 ? 102 THR   B O    1 
ATOM   6269  C  CB   . THR   B 1 103 ? 10.693  28.860  40.287  1.00 29.78 ? 102 THR   B CB   1 
ATOM   6270  O  OG1  . THR   B 1 103 ? 10.115  29.439  41.471  1.00 27.19 ? 102 THR   B OG1  1 
ATOM   6271  C  CG2  . THR   B 1 103 ? 10.584  29.838  39.117  1.00 22.56 ? 102 THR   B CG2  1 
ATOM   6272  H  H    . THR   B 1 103 ? 10.606  26.833  41.731  1.00 28.97 ? 102 THR   B H    1 
ATOM   6273  H  HA   . THR   B 1 103 ? 9.096   27.727  39.717  1.00 27.24 ? 102 THR   B HA   1 
ATOM   6274  H  HB   . THR   B 1 103 ? 11.636  28.698  40.445  1.00 35.74 ? 102 THR   B HB   1 
ATOM   6275  H  HG1  . THR   B 1 103 ? 10.440  30.202  41.607  1.00 32.63 ? 102 THR   B HG1  1 
ATOM   6276  H  HG21 . THR   B 1 103 ? 10.655  30.751  39.440  1.00 27.07 ? 102 THR   B HG21 1 
ATOM   6277  H  HG22 . THR   B 1 103 ? 11.295  29.674  38.479  1.00 27.07 ? 102 THR   B HG22 1 
ATOM   6278  H  HG23 . THR   B 1 103 ? 9.729   29.728  38.671  1.00 27.07 ? 102 THR   B HG23 1 
ATOM   6279  N  N    . SER   B 1 104 ? 9.990   26.681  37.695  1.00 23.36 ? 103 SER   B N    1 
ATOM   6280  C  CA   . SER   B 1 104 ? 10.531  26.114  36.474  1.00 25.13 ? 103 SER   B CA   1 
ATOM   6281  C  C    . SER   B 1 104 ? 10.617  27.187  35.407  1.00 20.50 ? 103 SER   B C    1 
ATOM   6282  O  O    . SER   B 1 104 ? 10.435  28.374  35.672  1.00 20.82 ? 103 SER   B O    1 
ATOM   6283  C  CB   . SER   B 1 104 ? 9.677   24.940  36.002  1.00 25.70 ? 103 SER   B CB   1 
ATOM   6284  O  OG   . SER   B 1 104 ? 10.409  24.091  35.120  1.00 23.32 ? 103 SER   B OG   1 
ATOM   6285  H  H    . SER   B 1 104 ? 9.161   26.904  37.632  1.00 28.03 ? 103 SER   B H    1 
ATOM   6286  H  HA   . SER   B 1 104 ? 11.423  25.784  36.666  1.00 30.16 ? 103 SER   B HA   1 
ATOM   6287  H  HB2  . SER   B 1 104 ? 9.397   24.424  36.774  1.00 30.84 ? 103 SER   B HB2  1 
ATOM   6288  H  HB3  . SER   B 1 104 ? 8.900   25.284  35.533  1.00 30.84 ? 103 SER   B HB3  1 
ATOM   6289  H  HG   . SER   B 1 104 ? 11.199  24.007  35.393  1.00 27.98 ? 103 SER   B HG   1 
ATOM   6290  N  N    . ILE   B 1 105 ? 10.876  26.765  34.162  1.00 21.59 ? 104 ILE   B N    1 
ATOM   6291  C  CA   . ILE   B 1 105 ? 10.924  27.694  33.036  1.00 20.81 ? 104 ILE   B CA   1 
ATOM   6292  C  C    . ILE   B 1 105 ? 10.233  27.034  31.855  1.00 18.28 ? 104 ILE   B C    1 
ATOM   6293  O  O    . ILE   B 1 105 ? 10.586  25.911  31.500  1.00 17.48 ? 104 ILE   B O    1 
ATOM   6294  C  CB   . ILE   B 1 105 ? 12.359  28.070  32.610  1.00 21.49 ? 104 ILE   B CB   1 
ATOM   6295  C  CG1  . ILE   B 1 105 ? 13.297  28.307  33.777  1.00 22.07 ? 104 ILE   B CG1  1 
ATOM   6296  C  CG2  . ILE   B 1 105 ? 12.312  29.308  31.698  1.00 23.51 ? 104 ILE   B CG2  1 
ATOM   6297  C  CD1  . ILE   B 1 105 ? 14.749  28.607  33.347  1.00 21.39 ? 104 ILE   B CD1  1 
ATOM   6298  H  H    . ILE   B 1 105 ? 11.026  25.946  33.949  1.00 25.91 ? 104 ILE   B H    1 
ATOM   6299  H  HA   . ILE   B 1 105 ? 10.458  28.503  33.300  1.00 24.97 ? 104 ILE   B HA   1 
ATOM   6300  H  HB   . ILE   B 1 105 ? 12.719  27.308  32.131  1.00 25.78 ? 104 ILE   B HB   1 
ATOM   6301  H  HG12 . ILE   B 1 105 ? 12.975  29.067  34.288  1.00 26.49 ? 104 ILE   B HG12 1 
ATOM   6302  H  HG13 . ILE   B 1 105 ? 13.309  27.514  34.335  1.00 26.49 ? 104 ILE   B HG13 1 
ATOM   6303  H  HG21 . ILE   B 1 105 ? 13.200  29.474  31.346  1.00 28.21 ? 104 ILE   B HG21 1 
ATOM   6304  H  HG22 . ILE   B 1 105 ? 11.693  29.141  30.970  1.00 28.21 ? 104 ILE   B HG22 1 
ATOM   6305  H  HG23 . ILE   B 1 105 ? 12.014  30.071  32.217  1.00 28.21 ? 104 ILE   B HG23 1 
ATOM   6306  H  HD11 . ILE   B 1 105 ? 15.338  28.463  34.104  1.00 25.66 ? 104 ILE   B HD11 1 
ATOM   6307  H  HD12 . ILE   B 1 105 ? 14.992  28.012  32.621  1.00 25.66 ? 104 ILE   B HD12 1 
ATOM   6308  H  HD13 . ILE   B 1 105 ? 14.807  29.530  33.053  1.00 25.66 ? 104 ILE   B HD13 1 
ATOM   6309  N  N    . LYS   B 1 106 ? 9.265   27.721  31.244  1.00 22.81 ? 105 LYS   B N    1 
ATOM   6310  C  CA   . LYS   B 1 106 ? 8.673   27.203  30.007  1.00 23.01 ? 105 LYS   B CA   1 
ATOM   6311  C  C    . LYS   B 1 106 ? 9.732   27.155  28.894  1.00 21.80 ? 105 LYS   B C    1 
ATOM   6312  O  O    . LYS   B 1 106 ? 10.549  28.070  28.760  1.00 20.42 ? 105 LYS   B O    1 
ATOM   6313  C  CB   . LYS   B 1 106 ? 7.491   28.077  29.590  1.00 25.78 ? 105 LYS   B CB   1 
ATOM   6314  C  CG   . LYS   B 1 106 ? 6.823   27.612  28.272  1.00 23.54 ? 105 LYS   B CG   1 
ATOM   6315  C  CD   . LYS   B 1 106 ? 5.500   28.310  28.064  1.00 28.09 ? 105 LYS   B CD   1 
ATOM   6316  C  CE   . LYS   B 1 106 ? 4.861   27.966  26.724  1.00 31.91 ? 105 LYS   B CE   1 
ATOM   6317  N  NZ   . LYS   B 1 106 ? 4.180   29.185  26.197  1.00 43.14 ? 105 LYS   B NZ   1 
ATOM   6318  H  H    . LYS   B 1 106 ? 8.941   28.469  31.517  1.00 27.38 ? 105 LYS   B H    1 
ATOM   6319  H  HA   . LYS   B 1 106 ? 8.343   26.302  30.148  1.00 27.61 ? 105 LYS   B HA   1 
ATOM   6320  H  HB2  . LYS   B 1 106 ? 6.819   28.051  30.289  1.00 30.94 ? 105 LYS   B HB2  1 
ATOM   6321  H  HB3  . LYS   B 1 106 ? 7.802   28.986  29.462  1.00 30.94 ? 105 LYS   B HB3  1 
ATOM   6322  H  HG2  . LYS   B 1 106 ? 7.403   27.824  27.523  1.00 28.25 ? 105 LYS   B HG2  1 
ATOM   6323  H  HG3  . LYS   B 1 106 ? 6.664   26.656  28.309  1.00 28.25 ? 105 LYS   B HG3  1 
ATOM   6324  H  HD2  . LYS   B 1 106 ? 4.887   28.042  28.767  1.00 33.71 ? 105 LYS   B HD2  1 
ATOM   6325  H  HD3  . LYS   B 1 106 ? 5.640   29.269  28.092  1.00 33.71 ? 105 LYS   B HD3  1 
ATOM   6326  H  HE2  . LYS   B 1 106 ? 5.541   27.684  26.093  1.00 38.29 ? 105 LYS   B HE2  1 
ATOM   6327  H  HE3  . LYS   B 1 106 ? 4.204   27.261  26.840  1.00 38.29 ? 105 LYS   B HE3  1 
ATOM   6328  H  HZ1  . LYS   B 1 106 ? 3.754   28.992  25.439  1.00 51.77 ? 105 LYS   B HZ1  1 
ATOM   6329  H  HZ2  . LYS   B 1 106 ? 3.590   29.486  26.791  1.00 51.77 ? 105 LYS   B HZ2  1 
ATOM   6330  H  HZ3  . LYS   B 1 106 ? 4.780   29.823  26.037  1.00 51.77 ? 105 LYS   B HZ3  1 
ATOM   6331  N  N    . TRP   B 1 107 ? 9.713   26.085  28.091  1.00 19.52 ? 106 TRP   B N    1 
ATOM   6332  C  CA   . TRP   B 1 107 ? 10.788  25.890  27.118  1.00 20.25 ? 106 TRP   B CA   1 
ATOM   6333  C  C    . TRP   B 1 107 ? 10.841  27.082  26.164  1.00 20.61 ? 106 TRP   B C    1 
ATOM   6334  O  O    . TRP   B 1 107 ? 9.813   27.514  25.629  1.00 21.53 ? 106 TRP   B O    1 
ATOM   6335  C  CB   . TRP   B 1 107 ? 10.625  24.600  26.301  1.00 20.05 ? 106 TRP   B CB   1 
ATOM   6336  C  CG   . TRP   B 1 107 ? 11.844  24.425  25.459  1.00 21.50 ? 106 TRP   B CG   1 
ATOM   6337  C  CD1  . TRP   B 1 107 ? 12.981  23.780  25.811  1.00 19.81 ? 106 TRP   B CD1  1 
ATOM   6338  C  CD2  . TRP   B 1 107 ? 12.097  25.001  24.140  1.00 21.04 ? 106 TRP   B CD2  1 
ATOM   6339  N  NE1  . TRP   B 1 107 ? 13.929  23.894  24.802  1.00 24.51 ? 106 TRP   B NE1  1 
ATOM   6340  C  CE2  . TRP   B 1 107 ? 13.415  24.643  23.778  1.00 22.45 ? 106 TRP   B CE2  1 
ATOM   6341  C  CE3  . TRP   B 1 107 ? 11.340  25.779  23.260  1.00 23.18 ? 106 TRP   B CE3  1 
ATOM   6342  C  CZ2  . TRP   B 1 107 ? 13.993  24.997  22.523  1.00 21.22 ? 106 TRP   B CZ2  1 
ATOM   6343  C  CZ3  . TRP   B 1 107 ? 11.921  26.163  22.026  1.00 19.91 ? 106 TRP   B CZ3  1 
ATOM   6344  C  CH2  . TRP   B 1 107 ? 13.237  25.778  21.683  1.00 20.67 ? 106 TRP   B CH2  1 
ATOM   6345  H  H    . TRP   B 1 107 ? 9.105   25.477  28.091  1.00 23.43 ? 106 TRP   B H    1 
ATOM   6346  H  HA   . TRP   B 1 107 ? 11.619  25.810  27.611  1.00 24.30 ? 106 TRP   B HA   1 
ATOM   6347  H  HB2  . TRP   B 1 107 ? 10.536  23.838  26.895  1.00 24.05 ? 106 TRP   B HB2  1 
ATOM   6348  H  HB3  . TRP   B 1 107 ? 9.847   24.665  25.726  1.00 24.05 ? 106 TRP   B HB3  1 
ATOM   6349  H  HD1  . TRP   B 1 107 ? 13.109  23.326  26.613  1.00 23.78 ? 106 TRP   B HD1  1 
ATOM   6350  H  HE1  . TRP   B 1 107 ? 14.716  23.547  24.818  1.00 29.41 ? 106 TRP   B HE1  1 
ATOM   6351  H  HE3  . TRP   B 1 107 ? 10.475  26.040  23.479  1.00 27.81 ? 106 TRP   B HE3  1 
ATOM   6352  H  HZ2  . TRP   B 1 107 ? 14.845  24.712  22.284  1.00 25.46 ? 106 TRP   B HZ2  1 
ATOM   6353  H  HZ3  . TRP   B 1 107 ? 11.426  26.677  21.430  1.00 23.89 ? 106 TRP   B HZ3  1 
ATOM   6354  H  HH2  . TRP   B 1 107 ? 13.598  26.058  20.873  1.00 24.81 ? 106 TRP   B HH2  1 
ATOM   6355  N  N    . ALA   B 1 108 ? 12.041  27.614  25.978  1.00 19.45 ? 107 ALA   B N    1 
ATOM   6356  C  CA   . ALA   B 1 108 ? 12.338  28.650  24.995  1.00 18.83 ? 107 ALA   B CA   1 
ATOM   6357  C  C    . ALA   B 1 108 ? 13.846  28.721  24.784  1.00 22.82 ? 107 ALA   B C    1 
ATOM   6358  O  O    . ALA   B 1 108 ? 14.622  28.544  25.718  1.00 19.70 ? 107 ALA   B O    1 
ATOM   6359  C  CB   . ALA   B 1 108 ? 11.802  30.017  25.426  1.00 22.17 ? 107 ALA   B CB   1 
ATOM   6360  H  H    . ALA   B 1 108 ? 12.736  27.382  26.430  1.00 23.34 ? 107 ALA   B H    1 
ATOM   6361  H  HA   . ALA   B 1 108 ? 11.920  28.411  24.153  1.00 22.59 ? 107 ALA   B HA   1 
ATOM   6362  H  HB1  . ALA   B 1 108 ? 12.415  30.705  25.125  1.00 26.61 ? 107 ALA   B HB1  1 
ATOM   6363  H  HB2  . ALA   B 1 108 ? 10.929  30.154  25.026  1.00 26.61 ? 107 ALA   B HB2  1 
ATOM   6364  H  HB3  . ALA   B 1 108 ? 11.730  30.037  26.393  1.00 26.61 ? 107 ALA   B HB3  1 
ATOM   6365  N  N    . ASP   B 1 109 ? 14.274  29.007  23.537  1.00 18.79 ? 108 ASP   B N    1 
ATOM   6366  C  CA   . ASP   B 1 109 ? 15.660  29.423  23.343  1.00 17.24 ? 108 ASP   B CA   1 
ATOM   6367  C  C    . ASP   B 1 109 ? 16.678  28.414  23.887  1.00 15.31 ? 108 ASP   B C    1 
ATOM   6368  O  O    . ASP   B 1 109 ? 17.694  28.795  24.454  1.00 20.97 ? 108 ASP   B O    1 
ATOM   6369  C  CB   . ASP   B 1 109 ? 15.936  30.802  23.997  1.00 22.02 ? 108 ASP   B CB   1 
ATOM   6370  C  CG   . ASP   B 1 109 ? 15.058  31.929  23.465  1.00 29.34 ? 108 ASP   B CG   1 
ATOM   6371  O  OD1  . ASP   B 1 109 ? 15.016  32.104  22.240  1.00 26.42 ? 108 ASP   B OD1  1 
ATOM   6372  O  OD2  . ASP   B 1 109 ? 14.454  32.692  24.273  1.00 26.26 ? 108 ASP   B OD2  1 
ATOM   6373  H  H    . ASP   B 1 109 ? 13.794  28.966  22.824  1.00 22.55 ? 108 ASP   B H    1 
ATOM   6374  H  HA   . ASP   B 1 109 ? 15.787  29.480  22.383  1.00 20.69 ? 108 ASP   B HA   1 
ATOM   6375  H  HB2  . ASP   B 1 109 ? 15.778  30.731  24.951  1.00 26.43 ? 108 ASP   B HB2  1 
ATOM   6376  H  HB3  . ASP   B 1 109 ? 16.860  31.046  23.831  1.00 26.43 ? 108 ASP   B HB3  1 
ATOM   6377  N  N    . ASN   B 1 110 ? 16.421  27.119  23.702  1.00 18.34 ? 109 ASN   B N    1 
ATOM   6378  C  CA   . ASN   B 1 110 ? 17.304  26.062  24.179  1.00 20.15 ? 109 ASN   B CA   1 
ATOM   6379  C  C    . ASN   B 1 110 ? 17.615  26.187  25.674  1.00 18.97 ? 109 ASN   B C    1 
ATOM   6380  O  O    . ASN   B 1 110 ? 18.749  25.978  26.108  1.00 19.29 ? 109 ASN   B O    1 
ATOM   6381  C  CB   . ASN   B 1 110 ? 18.609  26.052  23.405  1.00 21.32 ? 109 ASN   B CB   1 
ATOM   6382  C  CG   . ASN   B 1 110 ? 18.433  25.591  21.972  1.00 27.68 ? 109 ASN   B CG   1 
ATOM   6383  O  OD1  . ASN   B 1 110 ? 17.512  24.827  21.652  1.00 24.21 ? 109 ASN   B OD1  1 
ATOM   6384  N  ND2  . ASN   B 1 110 ? 19.331  26.043  21.102  1.00 33.51 ? 109 ASN   B ND2  1 
ATOM   6385  H  H    . ASN   B 1 110 ? 15.725  26.822  23.294  1.00 22.00 ? 109 ASN   B H    1 
ATOM   6386  H  HA   . ASN   B 1 110 ? 16.833  25.225  24.041  1.00 24.18 ? 109 ASN   B HA   1 
ATOM   6387  H  HB2  . ASN   B 1 110 ? 18.974  26.950  23.390  1.00 25.58 ? 109 ASN   B HB2  1 
ATOM   6388  H  HB3  . ASN   B 1 110 ? 19.230  25.448  23.841  1.00 25.58 ? 109 ASN   B HB3  1 
ATOM   6389  H  HD21 . ASN   B 1 110 ? 19.962  26.564  21.366  1.00 40.21 ? 109 ASN   B HD21 1 
ATOM   6390  H  HD22 . ASN   B 1 110 ? 19.280  25.814  20.274  1.00 40.21 ? 109 ASN   B HD22 1 
ATOM   6391  N  N    . ASN   B 1 111 ? 16.607  26.518  26.460  1.00 19.84 ? 110 ASN   B N    1 
ATOM   6392  C  CA   . ASN   B 1 111 ? 16.833  26.769  27.884  1.00 18.30 ? 110 ASN   B CA   1 
ATOM   6393  C  C    . ASN   B 1 111 ? 16.546  25.573  28.781  1.00 19.40 ? 110 ASN   B C    1 
ATOM   6394  O  O    . ASN   B 1 111 ? 16.426  25.758  30.001  1.00 17.91 ? 110 ASN   B O    1 
ATOM   6395  C  CB   . ASN   B 1 111 ? 16.028  27.984  28.339  1.00 16.20 ? 110 ASN   B CB   1 
ATOM   6396  C  CG   . ASN   B 1 111 ? 14.514  27.732  28.385  1.00 16.69 ? 110 ASN   B CG   1 
ATOM   6397  O  OD1  . ASN   B 1 111 ? 14.013  26.648  28.084  1.00 17.00 ? 110 ASN   B OD1  1 
ATOM   6398  N  ND2  . ASN   B 1 111 ? 13.791  28.759  28.774  1.00 21.95 ? 110 ASN   B ND2  1 
ATOM   6399  H  H    . ASN   B 1 111 ? 15.792  26.605  26.201  1.00 23.81 ? 110 ASN   B H    1 
ATOM   6400  H  HA   . ASN   B 1 111 ? 17.776  26.969  27.993  1.00 21.96 ? 110 ASN   B HA   1 
ATOM   6401  H  HB2  . ASN   B 1 111 ? 16.315  28.234  29.231  1.00 19.44 ? 110 ASN   B HB2  1 
ATOM   6402  H  HB3  . ASN   B 1 111 ? 16.188  28.715  27.722  1.00 19.44 ? 110 ASN   B HB3  1 
ATOM   6403  H  HD21 . ASN   B 1 111 ? 12.935  28.689  28.823  1.00 26.34 ? 110 ASN   B HD21 1 
ATOM   6404  H  HD22 . ASN   B 1 111 ? 14.174  29.502  28.978  1.00 26.34 ? 110 ASN   B HD22 1 
ATOM   6405  N  N    . SER   B 1 112 ? 16.462  24.357  28.243  1.00 17.97 ? 111 SER   B N    1 
ATOM   6406  C  CA   . SER   B 1 112 ? 16.160  23.207  29.112  1.00 19.49 ? 111 SER   B CA   1 
ATOM   6407  C  C    . SER   B 1 112 ? 17.239  22.999  30.177  1.00 23.86 ? 111 SER   B C    1 
ATOM   6408  O  O    . SER   B 1 112 ? 16.932  22.572  31.316  1.00 19.68 ? 111 SER   B O    1 
ATOM   6409  C  CB   . SER   B 1 112 ? 15.991  21.931  28.282  1.00 18.47 ? 111 SER   B CB   1 
ATOM   6410  O  OG   . SER   B 1 112 ? 17.218  21.450  27.709  1.00 19.35 ? 111 SER   B OG   1 
ATOM   6411  H  H    . SER   B 1 112 ? 16.571  24.172  27.410  1.00 21.56 ? 111 SER   B H    1 
ATOM   6412  H  HA   . SER   B 1 112 ? 15.319  23.383  29.562  1.00 23.39 ? 111 SER   B HA   1 
ATOM   6413  H  HB2  . SER   B 1 112 ? 15.631  21.238  28.858  1.00 22.16 ? 111 SER   B HB2  1 
ATOM   6414  H  HB3  . SER   B 1 112 ? 15.371  22.117  27.560  1.00 22.16 ? 111 SER   B HB3  1 
ATOM   6415  H  HG   . SER   B 1 112 ? 17.068  21.101  26.960  1.00 23.22 ? 111 SER   B HG   1 
ATOM   6416  N  N    . TYR   B 1 113 ? 18.507  23.291  29.836  1.00 15.33 ? 112 TYR   B N    1 
ATOM   6417  C  CA   . TYR   B 1 113 ? 19.589  23.140  30.803  1.00 18.99 ? 112 TYR   B CA   1 
ATOM   6418  C  C    . TYR   B 1 113 ? 19.435  24.129  31.957  1.00 17.54 ? 112 TYR   B C    1 
ATOM   6419  O  O    . TYR   B 1 113 ? 19.730  23.795  33.109  1.00 18.40 ? 112 TYR   B O    1 
ATOM   6420  C  CB   . TYR   B 1 113 ? 20.949  23.321  30.122  1.00 14.06 ? 112 TYR   B CB   1 
ATOM   6421  C  CG   . TYR   B 1 113 ? 21.364  24.731  29.848  1.00 17.00 ? 112 TYR   B CG   1 
ATOM   6422  C  CD1  . TYR   B 1 113 ? 20.822  25.453  28.788  1.00 15.98 ? 112 TYR   B CD1  1 
ATOM   6423  C  CD2  . TYR   B 1 113 ? 22.353  25.346  30.620  1.00 20.55 ? 112 TYR   B CD2  1 
ATOM   6424  C  CE1  . TYR   B 1 113 ? 21.231  26.765  28.541  1.00 18.08 ? 112 TYR   B CE1  1 
ATOM   6425  C  CE2  . TYR   B 1 113 ? 22.773  26.624  30.361  1.00 18.20 ? 112 TYR   B CE2  1 
ATOM   6426  C  CZ   . TYR   B 1 113 ? 22.230  27.330  29.311  1.00 18.53 ? 112 TYR   B CZ   1 
ATOM   6427  O  OH   . TYR   B 1 113 ? 22.667  28.611  29.086  1.00 19.51 ? 112 TYR   B OH   1 
ATOM   6428  H  H    . TYR   B 1 113 ? 18.756  23.574  29.063  1.00 18.39 ? 112 TYR   B H    1 
ATOM   6429  H  HA   . TYR   B 1 113 ? 19.556  22.239  31.163  1.00 22.78 ? 112 TYR   B HA   1 
ATOM   6430  H  HB2  . TYR   B 1 113 ? 21.628  22.929  30.693  1.00 16.88 ? 112 TYR   B HB2  1 
ATOM   6431  H  HB3  . TYR   B 1 113 ? 20.925  22.858  29.270  1.00 16.88 ? 112 TYR   B HB3  1 
ATOM   6432  H  HD1  . TYR   B 1 113 ? 20.183  25.058  28.240  1.00 19.18 ? 112 TYR   B HD1  1 
ATOM   6433  H  HD2  . TYR   B 1 113 ? 22.735  24.876  31.326  1.00 24.66 ? 112 TYR   B HD2  1 
ATOM   6434  H  HE1  . TYR   B 1 113 ? 20.832  27.258  27.861  1.00 21.69 ? 112 TYR   B HE1  1 
ATOM   6435  H  HE2  . TYR   B 1 113 ? 23.426  27.016  30.895  1.00 21.84 ? 112 TYR   B HE2  1 
ATOM   6436  H  HH   . TYR   B 1 113 ? 23.471  28.685  29.316  1.00 23.41 ? 112 TYR   B HH   1 
ATOM   6437  N  N    . LEU   B 1 114 ? 18.947  25.335  31.670  1.00 16.55 ? 113 LEU   B N    1 
ATOM   6438  C  CA   . LEU   B 1 114 ? 18.746  26.344  32.705  1.00 19.75 ? 113 LEU   B CA   1 
ATOM   6439  C  C    . LEU   B 1 114 ? 17.560  25.981  33.582  1.00 19.89 ? 113 LEU   B C    1 
ATOM   6440  O  O    . LEU   B 1 114 ? 17.607  26.159  34.813  1.00 18.99 ? 113 LEU   B O    1 
ATOM   6441  C  CB   . LEU   B 1 114 ? 18.537  27.708  32.042  1.00 18.89 ? 113 LEU   B CB   1 
ATOM   6442  C  CG   . LEU   B 1 114 ? 19.800  28.392  31.521  1.00 30.64 ? 113 LEU   B CG   1 
ATOM   6443  C  CD1  . LEU   B 1 114 ? 19.448  29.709  30.814  1.00 29.18 ? 113 LEU   B CD1  1 
ATOM   6444  C  CD2  . LEU   B 1 114 ? 20.802  28.643  32.662  1.00 30.24 ? 113 LEU   B CD2  1 
ATOM   6445  H  H    . LEU   B 1 114 ? 18.725  25.596  30.881  1.00 19.86 ? 113 LEU   B H    1 
ATOM   6446  H  HA   . LEU   B 1 114 ? 19.531  26.399  33.272  1.00 23.70 ? 113 LEU   B HA   1 
ATOM   6447  H  HB2  . LEU   B 1 114 ? 17.941  27.589  31.286  1.00 22.67 ? 113 LEU   B HB2  1 
ATOM   6448  H  HB3  . LEU   B 1 114 ? 18.134  28.303  32.692  1.00 22.67 ? 113 LEU   B HB3  1 
ATOM   6449  H  HG   . LEU   B 1 114 ? 20.227  27.806  30.876  1.00 36.76 ? 113 LEU   B HG   1 
ATOM   6450  H  HD11 . LEU   B 1 114 ? 20.247  30.065  30.394  1.00 35.02 ? 113 LEU   B HD11 1 
ATOM   6451  H  HD12 . LEU   B 1 114 ? 18.770  29.535  30.143  1.00 35.02 ? 113 LEU   B HD12 1 
ATOM   6452  H  HD13 . LEU   B 1 114 ? 19.111  30.339  31.470  1.00 35.02 ? 113 LEU   B HD13 1 
ATOM   6453  H  HD21 . LEU   B 1 114 ? 21.358  29.404  32.433  1.00 36.28 ? 113 LEU   B HD21 1 
ATOM   6454  H  HD22 . LEU   B 1 114 ? 20.311  28.827  33.478  1.00 36.28 ? 113 LEU   B HD22 1 
ATOM   6455  H  HD23 . LEU   B 1 114 ? 21.353  27.854  32.778  1.00 36.28 ? 113 LEU   B HD23 1 
ATOM   6456  N  N    . ALA   B 1 115 ? 16.474  25.478  32.981  1.00 19.66 ? 114 ALA   B N    1 
ATOM   6457  C  CA   . ALA   B 1 115 ? 15.366  25.003  33.822  1.00 22.04 ? 114 ALA   B CA   1 
ATOM   6458  C  C    . ALA   B 1 115 ? 15.816  23.874  34.753  1.00 20.10 ? 114 ALA   B C    1 
ATOM   6459  O  O    . ALA   B 1 115 ? 15.493  23.875  35.955  1.00 17.37 ? 114 ALA   B O    1 
ATOM   6460  C  CB   . ALA   B 1 115 ? 14.190  24.537  32.970  1.00 21.80 ? 114 ALA   B CB   1 
ATOM   6461  H  H    . ALA   B 1 115 ? 16.358  25.404  32.132  1.00 23.60 ? 114 ALA   B H    1 
ATOM   6462  H  HA   . ALA   B 1 115 ? 15.064  25.750  34.362  1.00 26.45 ? 114 ALA   B HA   1 
ATOM   6463  H  HB1  . ALA   B 1 115 ? 13.568  24.048  33.531  1.00 26.17 ? 114 ALA   B HB1  1 
ATOM   6464  H  HB2  . ALA   B 1 115 ? 13.750  25.313  32.587  1.00 26.17 ? 114 ALA   B HB2  1 
ATOM   6465  H  HB3  . ALA   B 1 115 ? 14.520  23.962  32.263  1.00 26.17 ? 114 ALA   B HB3  1 
ATOM   6466  N  N    . THR   B 1 116 ? 16.574  22.909  34.223  1.00 16.71 ? 115 THR   B N    1 
ATOM   6467  C  CA   . THR   B 1 116 ? 17.040  21.800  35.044  1.00 18.88 ? 115 THR   B CA   1 
ATOM   6468  C  C    . THR   B 1 116 ? 17.968  22.296  36.150  1.00 18.07 ? 115 THR   B C    1 
ATOM   6469  O  O    . THR   B 1 116 ? 17.860  21.844  37.305  1.00 19.30 ? 115 THR   B O    1 
ATOM   6470  C  CB   . THR   B 1 116 ? 17.711  20.749  34.152  1.00 23.61 ? 115 THR   B CB   1 
ATOM   6471  O  OG1  . THR   B 1 116 ? 16.748  20.298  33.201  1.00 28.14 ? 115 THR   B OG1  1 
ATOM   6472  C  CG2  . THR   B 1 116 ? 18.139  19.541  34.998  1.00 24.73 ? 115 THR   B CG2  1 
ATOM   6473  H  H    . THR   B 1 116 ? 16.827  22.877  33.401  1.00 20.05 ? 115 THR   B H    1 
ATOM   6474  H  HA   . THR   B 1 116 ? 16.286  21.369  35.477  1.00 22.65 ? 115 THR   B HA   1 
ATOM   6475  H  HB   . THR   B 1 116 ? 18.490  21.126  33.714  1.00 28.33 ? 115 THR   B HB   1 
ATOM   6476  H  HG1  . THR   B 1 116 ? 16.296  19.668  33.526  1.00 33.77 ? 115 THR   B HG1  1 
ATOM   6477  H  HG21 . THR   B 1 116 ? 18.300  18.775  34.425  1.00 29.67 ? 115 THR   B HG21 1 
ATOM   6478  H  HG22 . THR   B 1 116 ? 18.953  19.747  35.484  1.00 29.67 ? 115 THR   B HG22 1 
ATOM   6479  H  HG23 . THR   B 1 116 ? 17.441  19.317  35.633  1.00 29.67 ? 115 THR   B HG23 1 
ATOM   6480  N  N    . ALA   B 1 117 ? 18.872  23.242  35.828  1.00 19.77 ? 116 ALA   B N    1 
ATOM   6481  C  CA   . ALA   B 1 117 ? 19.746  23.818  36.853  1.00 22.13 ? 116 ALA   B CA   1 
ATOM   6482  C  C    . ALA   B 1 117 ? 18.942  24.578  37.909  1.00 17.75 ? 116 ALA   B C    1 
ATOM   6483  O  O    . ALA   B 1 117 ? 19.185  24.419  39.118  1.00 19.44 ? 116 ALA   B O    1 
ATOM   6484  C  CB   . ALA   B 1 117 ? 20.790  24.745  36.218  1.00 19.79 ? 116 ALA   B CB   1 
ATOM   6485  H  H    . ALA   B 1 117 ? 18.993  23.558  35.037  1.00 23.72 ? 116 ALA   B H    1 
ATOM   6486  H  HA   . ALA   B 1 117 ? 20.218  23.091  37.289  1.00 26.56 ? 116 ALA   B HA   1 
ATOM   6487  H  HB1  . ALA   B 1 117 ? 21.228  25.254  36.918  1.00 23.74 ? 116 ALA   B HB1  1 
ATOM   6488  H  HB2  . ALA   B 1 117 ? 21.442  24.207  35.742  1.00 23.74 ? 116 ALA   B HB2  1 
ATOM   6489  H  HB3  . ALA   B 1 117 ? 20.344  25.347  35.602  1.00 23.74 ? 116 ALA   B HB3  1 
ATOM   6490  N  N    . LEU   B 1 118 ? 17.972  25.391  37.476  1.00 18.84 ? 117 LEU   B N    1 
ATOM   6491  C  CA   . LEU   B 1 118 ? 17.170  26.178  38.408  1.00 21.25 ? 117 LEU   B CA   1 
ATOM   6492  C  C    . LEU   B 1 118 ? 16.412  25.273  39.367  1.00 18.17 ? 117 LEU   B C    1 
ATOM   6493  O  O    . LEU   B 1 118 ? 16.388  25.530  40.577  1.00 18.64 ? 117 LEU   B O    1 
ATOM   6494  C  CB   . LEU   B 1 118 ? 16.218  27.080  37.625  1.00 19.80 ? 117 LEU   B CB   1 
ATOM   6495  C  CG   . LEU   B 1 118 ? 15.182  27.842  38.463  1.00 19.86 ? 117 LEU   B CG   1 
ATOM   6496  C  CD1  . LEU   B 1 118 ? 15.821  28.807  39.459  1.00 23.34 ? 117 LEU   B CD1  1 
ATOM   6497  C  CD2  . LEU   B 1 118 ? 14.234  28.544  37.545  1.00 23.13 ? 117 LEU   B CD2  1 
ATOM   6498  H  H    . LEU   B 1 118 ? 17.761  25.503  36.649  1.00 22.61 ? 117 LEU   B H    1 
ATOM   6499  H  HA   . LEU   B 1 118 ? 17.752  26.746  38.937  1.00 25.50 ? 117 LEU   B HA   1 
ATOM   6500  H  HB2  . LEU   B 1 118 ? 16.746  27.740  37.150  1.00 23.76 ? 117 LEU   B HB2  1 
ATOM   6501  H  HB3  . LEU   B 1 118 ? 15.729  26.529  36.993  1.00 23.76 ? 117 LEU   B HB3  1 
ATOM   6502  H  HG   . LEU   B 1 118 ? 14.688  27.208  39.007  1.00 23.83 ? 117 LEU   B HG   1 
ATOM   6503  H  HD11 . LEU   B 1 118 ? 15.267  29.600  39.530  1.00 28.01 ? 117 LEU   B HD11 1 
ATOM   6504  H  HD12 . LEU   B 1 118 ? 15.887  28.371  40.323  1.00 28.01 ? 117 LEU   B HD12 1 
ATOM   6505  H  HD13 . LEU   B 1 118 ? 16.705  29.048  39.141  1.00 28.01 ? 117 LEU   B HD13 1 
ATOM   6506  H  HD21 . LEU   B 1 118 ? 13.445  28.805  38.044  1.00 27.75 ? 117 LEU   B HD21 1 
ATOM   6507  H  HD22 . LEU   B 1 118 ? 14.671  29.330  37.182  1.00 27.75 ? 117 LEU   B HD22 1 
ATOM   6508  H  HD23 . LEU   B 1 118 ? 13.987  27.942  36.826  1.00 27.75 ? 117 LEU   B HD23 1 
ATOM   6509  N  N    . LEU   B 1 119 ? 15.766  24.214  38.834  1.00 19.64 ? 118 LEU   B N    1 
ATOM   6510  C  CA   . LEU   B 1 119 ? 15.056  23.251  39.673  1.00 20.06 ? 118 LEU   B CA   1 
ATOM   6511  C  C    . LEU   B 1 119 ? 16.002  22.594  40.655  1.00 22.11 ? 118 LEU   B C    1 
ATOM   6512  O  O    . LEU   B 1 119 ? 15.659  22.421  41.832  1.00 20.22 ? 118 LEU   B O    1 
ATOM   6513  C  CB   . LEU   B 1 119 ? 14.394  22.182  38.815  1.00 19.20 ? 118 LEU   B CB   1 
ATOM   6514  C  CG   . LEU   B 1 119 ? 13.252  22.836  38.027  1.00 18.68 ? 118 LEU   B CG   1 
ATOM   6515  C  CD1  . LEU   B 1 119 ? 12.943  21.955  36.829  1.00 18.09 ? 118 LEU   B CD1  1 
ATOM   6516  C  CD2  . LEU   B 1 119 ? 11.975  23.070  38.843  1.00 19.74 ? 118 LEU   B CD2  1 
ATOM   6517  H  H    . LEU   B 1 119 ? 15.729  24.039  37.993  1.00 23.57 ? 118 LEU   B H    1 
ATOM   6518  H  HA   . LEU   B 1 119 ? 14.364  23.722  40.161  1.00 24.07 ? 118 LEU   B HA   1 
ATOM   6519  H  HB2  . LEU   B 1 119 ? 15.038  21.809  38.194  1.00 23.05 ? 118 LEU   B HB2  1 
ATOM   6520  H  HB3  . LEU   B 1 119 ? 14.032  21.481  39.380  1.00 23.05 ? 118 LEU   B HB3  1 
ATOM   6521  H  HG   . LEU   B 1 119 ? 13.545  23.720  37.756  1.00 22.42 ? 118 LEU   B HG   1 
ATOM   6522  H  HD11 . LEU   B 1 119 ? 12.327  22.423  36.244  1.00 21.70 ? 118 LEU   B HD11 1 
ATOM   6523  H  HD12 . LEU   B 1 119 ? 13.768  21.764  36.356  1.00 21.70 ? 118 LEU   B HD12 1 
ATOM   6524  H  HD13 . LEU   B 1 119 ? 12.541  21.129  37.140  1.00 21.70 ? 118 LEU   B HD13 1 
ATOM   6525  H  HD21 . LEU   B 1 119 ? 11.277  23.392  38.252  1.00 23.69 ? 118 LEU   B HD21 1 
ATOM   6526  H  HD22 . LEU   B 1 119 ? 11.703  22.233  39.251  1.00 23.69 ? 118 LEU   B HD22 1 
ATOM   6527  H  HD23 . LEU   B 1 119 ? 12.156  23.730  39.531  1.00 23.69 ? 118 LEU   B HD23 1 
ATOM   6528  N  N    . THR   B 1 120 ? 17.208  22.247  40.197  1.00 17.16 ? 119 THR   B N    1 
ATOM   6529  C  CA   . THR   B 1 120 ? 18.175  21.617  41.091  1.00 17.95 ? 119 THR   B CA   1 
ATOM   6530  C  C    . THR   B 1 120 ? 18.578  22.563  42.213  1.00 18.95 ? 119 THR   B C    1 
ATOM   6531  O  O    . THR   B 1 120 ? 18.649  22.158  43.386  1.00 22.97 ? 119 THR   B O    1 
ATOM   6532  C  CB   . THR   B 1 120 ? 19.411  21.175  40.310  1.00 20.95 ? 119 THR   B CB   1 
ATOM   6533  O  OG1  . THR   B 1 120 ? 19.035  20.265  39.254  1.00 19.04 ? 119 THR   B OG1  1 
ATOM   6534  C  CG2  . THR   B 1 120 ? 20.436  20.473  41.273  1.00 20.32 ? 119 THR   B CG2  1 
ATOM   6535  H  H    . THR   B 1 120 ? 17.483  22.365  39.390  1.00 20.59 ? 119 THR   B H    1 
ATOM   6536  H  HA   . THR   B 1 120 ? 17.766  20.828  41.481  1.00 21.54 ? 119 THR   B HA   1 
ATOM   6537  H  HB   . THR   B 1 120 ? 19.837  21.952  39.915  1.00 25.14 ? 119 THR   B HB   1 
ATOM   6538  H  HG1  . THR   B 1 120 ? 19.057  20.659  38.513  1.00 22.85 ? 119 THR   B HG1  1 
ATOM   6539  H  HG21 . THR   B 1 120 ? 21.279  20.954  41.267  1.00 24.38 ? 119 THR   B HG21 1 
ATOM   6540  H  HG22 . THR   B 1 120 ? 20.087  20.461  42.178  1.00 24.38 ? 119 THR   B HG22 1 
ATOM   6541  H  HG23 . THR   B 1 120 ? 20.592  19.561  40.983  1.00 24.38 ? 119 THR   B HG23 1 
ATOM   6542  N  N    . LEU   B 1 121 ? 18.852  23.831  41.877  1.00 16.92 ? 120 LEU   B N    1 
ATOM   6543  C  CA   . LEU   B 1 121 ? 19.295  24.785  42.905  1.00 19.52 ? 120 LEU   B CA   1 
ATOM   6544  C  C    . LEU   B 1 121 ? 18.257  25.005  43.999  1.00 22.64 ? 120 LEU   B C    1 
ATOM   6545  O  O    . LEU   B 1 121 ? 18.625  25.434  45.091  1.00 29.29 ? 120 LEU   B O    1 
ATOM   6546  C  CB   . LEU   B 1 121 ? 19.652  26.103  42.247  1.00 16.59 ? 120 LEU   B CB   1 
ATOM   6547  C  CG   . LEU   B 1 121 ? 20.920  26.038  41.374  1.00 22.49 ? 120 LEU   B CG   1 
ATOM   6548  C  CD1  . LEU   B 1 121 ? 21.034  27.179  40.372  1.00 26.03 ? 120 LEU   B CD1  1 
ATOM   6549  C  CD2  . LEU   B 1 121 ? 22.175  25.967  42.265  1.00 28.13 ? 120 LEU   B CD2  1 
ATOM   6550  H  H    . LEU   B 1 121 ? 18.791  24.156  41.083  1.00 20.30 ? 120 LEU   B H    1 
ATOM   6551  H  HA   . LEU   B 1 121 ? 20.089  24.432  43.336  1.00 23.42 ? 120 LEU   B HA   1 
ATOM   6552  H  HB2  . LEU   B 1 121 ? 18.915  26.377  41.679  1.00 19.90 ? 120 LEU   B HB2  1 
ATOM   6553  H  HB3  . LEU   B 1 121 ? 19.802  26.766  42.939  1.00 19.90 ? 120 LEU   B HB3  1 
ATOM   6554  H  HG   . LEU   B 1 121 ? 20.857  25.230  40.841  1.00 26.99 ? 120 LEU   B HG   1 
ATOM   6555  H  HD11 . LEU   B 1 121 ? 21.736  26.971  39.736  1.00 31.23 ? 120 LEU   B HD11 1 
ATOM   6556  H  HD12 . LEU   B 1 121 ? 20.188  27.279  39.910  1.00 31.23 ? 120 LEU   B HD12 1 
ATOM   6557  H  HD13 . LEU   B 1 121 ? 21.250  27.996  40.848  1.00 31.23 ? 120 LEU   B HD13 1 
ATOM   6558  H  HD21 . LEU   B 1 121 ? 22.953  26.200  41.735  1.00 33.76 ? 120 LEU   B HD21 1 
ATOM   6559  H  HD22 . LEU   B 1 121 ? 22.076  26.592  43.000  1.00 33.76 ? 120 LEU   B HD22 1 
ATOM   6560  H  HD23 . LEU   B 1 121 ? 22.268  25.064  42.609  1.00 33.76 ? 120 LEU   B HD23 1 
ATOM   6561  N  N    . GLN   B 1 122 ? 16.977  24.757  43.736  1.00 18.66 ? 121 GLN   B N    1 
ATOM   6562  C  CA   . GLN   B 1 122 ? 15.936  24.904  44.738  1.00 22.33 ? 121 GLN   B CA   1 
ATOM   6563  C  C    . GLN   B 1 122 ? 15.851  23.702  45.658  1.00 23.65 ? 121 GLN   B C    1 
ATOM   6564  O  O    . GLN   B 1 122 ? 15.041  23.705  46.593  1.00 23.73 ? 121 GLN   B O    1 
ATOM   6565  C  CB   . GLN   B 1 122 ? 14.586  25.137  44.055  1.00 19.74 ? 121 GLN   B CB   1 
ATOM   6566  C  CG   . GLN   B 1 122 ? 14.454  26.531  43.461  1.00 21.31 ? 121 GLN   B CG   1 
ATOM   6567  C  CD   . GLN   B 1 122 ? 13.305  26.629  42.519  1.00 24.13 ? 121 GLN   B CD   1 
ATOM   6568  O  OE1  . GLN   B 1 122 ? 12.207  26.953  42.918  1.00 18.59 ? 121 GLN   B OE1  1 
ATOM   6569  N  NE2  . GLN   B 1 122 ? 13.554  26.328  41.229  1.00 22.03 ? 121 GLN   B NE2  1 
ATOM   6570  H  H    . GLN   B 1 122 ? 16.685  24.497  42.971  1.00 22.39 ? 121 GLN   B H    1 
ATOM   6571  H  HA   . GLN   B 1 122 ? 16.124  25.684  45.283  1.00 26.79 ? 121 GLN   B HA   1 
ATOM   6572  H  HB2  . GLN   B 1 122 ? 14.481  24.494  43.336  1.00 23.69 ? 121 GLN   B HB2  1 
ATOM   6573  H  HB3  . GLN   B 1 122 ? 13.878  25.022  44.708  1.00 23.69 ? 121 GLN   B HB3  1 
ATOM   6574  H  HG2  . GLN   B 1 122 ? 14.316  27.171  44.177  1.00 25.57 ? 121 GLN   B HG2  1 
ATOM   6575  H  HG3  . GLN   B 1 122 ? 15.265  26.748  42.974  1.00 25.57 ? 121 GLN   B HG3  1 
ATOM   6576  H  HE21 . GLN   B 1 122 ? 14.345  26.094  40.987  1.00 26.43 ? 121 GLN   B HE21 1 
ATOM   6577  H  HE22 . GLN   B 1 122 ? 12.921  26.371  40.647  1.00 26.43 ? 121 GLN   B HE22 1 
ATOM   6578  N  N    . GLN   B 1 123 ? 16.647  22.676  45.404  1.00 21.79 ? 122 GLN   B N    1 
ATOM   6579  C  CA   . GLN   B 1 123 ? 16.597  21.446  46.166  1.00 23.92 ? 122 GLN   B CA   1 
ATOM   6580  C  C    . GLN   B 1 123 ? 17.904  21.145  46.884  1.00 32.06 ? 122 GLN   B C    1 
ATOM   6581  O  O    . GLN   B 1 123 ? 17.926  20.254  47.741  1.00 30.98 ? 122 GLN   B O    1 
ATOM   6582  C  CB   . GLN   B 1 123 ? 16.251  20.259  45.254  1.00 20.65 ? 122 GLN   B CB   1 
ATOM   6583  C  CG   . GLN   B 1 123 ? 14.846  20.307  44.681  1.00 21.71 ? 122 GLN   B CG   1 
ATOM   6584  C  CD   . GLN   B 1 123 ? 14.609  19.223  43.671  1.00 24.57 ? 122 GLN   B CD   1 
ATOM   6585  O  OE1  . GLN   B 1 123 ? 14.417  18.063  44.027  1.00 23.66 ? 122 GLN   B OE1  1 
ATOM   6586  N  NE2  . GLN   B 1 123 ? 14.622  19.595  42.390  1.00 22.13 ? 122 GLN   B NE2  1 
ATOM   6587  H  H    . GLN   B 1 123 ? 17.237  22.670  44.779  1.00 26.15 ? 122 GLN   B H    1 
ATOM   6588  H  HA   . GLN   B 1 123 ? 15.893  21.517  46.830  1.00 28.71 ? 122 GLN   B HA   1 
ATOM   6589  H  HB2  . GLN   B 1 123 ? 16.872  20.248  44.509  1.00 24.78 ? 122 GLN   B HB2  1 
ATOM   6590  H  HB3  . GLN   B 1 123 ? 16.332  19.440  45.766  1.00 24.78 ? 122 GLN   B HB3  1 
ATOM   6591  H  HG2  . GLN   B 1 123 ? 14.205  20.195  45.401  1.00 26.05 ? 122 GLN   B HG2  1 
ATOM   6592  H  HG3  . GLN   B 1 123 ? 14.709  21.163  44.245  1.00 26.05 ? 122 GLN   B HG3  1 
ATOM   6593  H  HE21 . GLN   B 1 123 ? 14.761  20.418  42.183  1.00 26.56 ? 122 GLN   B HE21 1 
ATOM   6594  H  HE22 . GLN   B 1 123 ? 14.491  19.011  41.772  1.00 26.56 ? 122 GLN   B HE22 1 
ATOM   6595  N  N    . ILE   B 1 124 ? 18.984  21.858  46.581  1.00 25.39 ? 123 ILE   B N    1 
ATOM   6596  C  CA   . ILE   B 1 124 ? 20.240  21.656  47.293  1.00 25.75 ? 123 ILE   B CA   1 
ATOM   6597  C  C    . ILE   B 1 124 ? 20.601  22.925  48.064  1.00 30.80 ? 123 ILE   B C    1 
ATOM   6598  O  O    . ILE   B 1 124 ? 20.081  24.005  47.797  1.00 26.12 ? 123 ILE   B O    1 
ATOM   6599  C  CB   . ILE   B 1 124 ? 21.379  21.225  46.348  1.00 26.62 ? 123 ILE   B CB   1 
ATOM   6600  C  CG1  . ILE   B 1 124 ? 21.597  22.223  45.207  1.00 30.79 ? 123 ILE   B CG1  1 
ATOM   6601  C  CG2  . ILE   B 1 124 ? 21.083  19.844  45.773  1.00 30.85 ? 123 ILE   B CG2  1 
ATOM   6602  C  CD1  . ILE   B 1 124 ? 22.925  21.965  44.466  1.00 29.70 ? 123 ILE   B CD1  1 
ATOM   6603  H  H    . ILE   B 1 124 ? 19.013  22.462  45.970  1.00 30.46 ? 123 ILE   B H    1 
ATOM   6604  H  HA   . ILE   B 1 124 ? 20.117  20.954  47.951  1.00 30.90 ? 123 ILE   B HA   1 
ATOM   6605  H  HB   . ILE   B 1 124 ? 22.193  21.200  46.875  1.00 31.94 ? 123 ILE   B HB   1 
ATOM   6606  H  HG12 . ILE   B 1 124 ? 20.872  22.142  44.568  1.00 36.95 ? 123 ILE   B HG12 1 
ATOM   6607  H  HG13 . ILE   B 1 124 ? 21.621  23.122  45.569  1.00 36.95 ? 123 ILE   B HG13 1 
ATOM   6608  H  HG21 . ILE   B 1 124 ? 21.916  19.356  45.679  1.00 37.02 ? 123 ILE   B HG21 1 
ATOM   6609  H  HG22 . ILE   B 1 124 ? 20.489  19.372  46.376  1.00 37.02 ? 123 ILE   B HG22 1 
ATOM   6610  H  HG23 . ILE   B 1 124 ? 20.661  19.947  44.905  1.00 37.02 ? 123 ILE   B HG23 1 
ATOM   6611  H  HD11 . ILE   B 1 124 ? 23.231  22.795  44.068  1.00 35.64 ? 123 ILE   B HD11 1 
ATOM   6612  H  HD12 . ILE   B 1 124 ? 23.583  21.640  45.100  1.00 35.64 ? 123 ILE   B HD12 1 
ATOM   6613  H  HD13 . ILE   B 1 124 ? 22.777  21.301  43.774  1.00 35.64 ? 123 ILE   B HD13 1 
ATOM   6614  N  N    . GLU   B 1 125 ? 21.430  22.757  49.109  1.00 27.55 ? 124 GLU   B N    1 
ATOM   6615  C  CA   . GLU   B 1 125 ? 21.815  23.865  49.995  1.00 26.71 ? 124 GLU   B CA   1 
ATOM   6616  C  C    . GLU   B 1 125 ? 23.083  24.555  49.522  1.00 31.39 ? 124 GLU   B C    1 
ATOM   6617  O  O    . GLU   B 1 125 ? 24.183  23.983  49.591  1.00 32.55 ? 124 GLU   B O    1 
ATOM   6618  C  CB   . GLU   B 1 125 ? 21.973  23.362  51.435  1.00 31.35 ? 124 GLU   B CB   1 
ATOM   6619  C  CG   . GLU   B 1 125 ? 22.282  24.465  52.422  1.00 35.45 ? 124 GLU   B CG   1 
ATOM   6620  C  CD   . GLU   B 1 125 ? 22.463  23.928  53.843  1.00 50.24 ? 124 GLU   B CD   1 
ATOM   6621  O  OE1  . GLU   B 1 125 ? 21.457  23.405  54.386  1.00 48.52 ? 124 GLU   B OE1  1 
ATOM   6622  O  OE2  . GLU   B 1 125 ? 23.602  23.994  54.386  1.00 48.04 ? 124 GLU   B OE2  1 
ATOM   6623  H  H    . GLU   B 1 125 ? 21.783  22.003  49.326  1.00 33.06 ? 124 GLU   B H    1 
ATOM   6624  H  HA   . GLU   B 1 125 ? 21.110  24.530  49.951  1.00 32.05 ? 124 GLU   B HA   1 
ATOM   6625  H  HB2  . GLU   B 1 125 ? 21.147  22.937  51.711  1.00 37.62 ? 124 GLU   B HB2  1 
ATOM   6626  H  HB3  . GLU   B 1 125 ? 22.702  22.723  51.465  1.00 37.62 ? 124 GLU   B HB3  1 
ATOM   6627  H  HG2  . GLU   B 1 125 ? 23.103  24.909  52.158  1.00 42.54 ? 124 GLU   B HG2  1 
ATOM   6628  H  HG3  . GLU   B 1 125 ? 21.549  25.101  52.429  1.00 42.54 ? 124 GLU   B HG3  1 
ATOM   6629  N  N    . LEU   B 1 126 ? 22.939  25.801  49.060  1.00 28.98 ? 125 LEU   B N    1 
ATOM   6630  C  CA   . LEU   B 1 126 ? 24.041  26.556  48.483  1.00 32.22 ? 125 LEU   B CA   1 
ATOM   6631  C  C    . LEU   B 1 126 ? 23.894  28.014  48.898  1.00 33.98 ? 125 LEU   B C    1 
ATOM   6632  O  O    . LEU   B 1 126 ? 22.784  28.557  48.902  1.00 35.86 ? 125 LEU   B O    1 
ATOM   6633  C  CB   . LEU   B 1 126 ? 24.037  26.409  46.944  1.00 33.63 ? 125 LEU   B CB   1 
ATOM   6634  C  CG   . LEU   B 1 126 ? 25.309  26.710  46.153  1.00 37.24 ? 125 LEU   B CG   1 
ATOM   6635  C  CD1  . LEU   B 1 126 ? 26.441  25.745  46.488  1.00 36.68 ? 125 LEU   B CD1  1 
ATOM   6636  C  CD2  . LEU   B 1 126 ? 25.048  26.696  44.632  1.00 39.17 ? 125 LEU   B CD2  1 
ATOM   6637  H  H    . LEU   B 1 126 ? 22.196  26.235  49.073  1.00 34.78 ? 125 LEU   B H    1 
ATOM   6638  H  HA   . LEU   B 1 126 ? 24.899  26.242  48.811  1.00 38.66 ? 125 LEU   B HA   1 
ATOM   6639  H  HB2  . LEU   B 1 126 ? 23.804  25.489  46.743  1.00 40.36 ? 125 LEU   B HB2  1 
ATOM   6640  H  HB3  . LEU   B 1 126 ? 23.356  27.007  46.599  1.00 40.36 ? 125 LEU   B HB3  1 
ATOM   6641  H  HG   . LEU   B 1 126 ? 25.594  27.601  46.410  1.00 44.68 ? 125 LEU   B HG   1 
ATOM   6642  H  HD11 . LEU   B 1 126 ? 27.019  25.655  45.714  1.00 44.02 ? 125 LEU   B HD11 1 
ATOM   6643  H  HD12 . LEU   B 1 126 ? 26.946  26.098  47.238  1.00 44.02 ? 125 LEU   B HD12 1 
ATOM   6644  H  HD13 . LEU   B 1 126 ? 26.063  24.883  46.721  1.00 44.02 ? 125 LEU   B HD13 1 
ATOM   6645  H  HD21 . LEU   B 1 126 ? 25.806  27.096  44.177  1.00 47.00 ? 125 LEU   B HD21 1 
ATOM   6646  H  HD22 . LEU   B 1 126 ? 24.934  25.778  44.339  1.00 47.00 ? 125 LEU   B HD22 1 
ATOM   6647  H  HD23 . LEU   B 1 126 ? 24.244  27.205  44.445  1.00 47.00 ? 125 LEU   B HD23 1 
ATOM   6648  N  N    . LYS   B 1 127 ? 25.004  28.649  49.259  1.00 26.07 ? 126 LYS   B N    1 
ATOM   6649  C  CA   . LYS   B 1 127 ? 25.001  30.069  49.574  1.00 32.18 ? 126 LYS   B CA   1 
ATOM   6650  C  C    . LYS   B 1 127 ? 25.904  30.757  48.570  1.00 31.00 ? 126 LYS   B C    1 
ATOM   6651  O  O    . LYS   B 1 127 ? 27.102  30.460  48.485  1.00 34.33 ? 126 LYS   B O    1 
ATOM   6652  C  CB   . LYS   B 1 127 ? 25.459  30.354  51.007  1.00 47.42 ? 126 LYS   B CB   1 
ATOM   6653  C  CG   . LYS   B 1 127 ? 24.729  31.554  51.642  1.00 57.62 ? 126 LYS   B CG   1 
ATOM   6654  C  CD   . LYS   B 1 127 ? 25.101  32.872  50.983  1.00 53.38 ? 126 LYS   B CD   1 
ATOM   6655  C  CE   . LYS   B 1 127 ? 24.657  34.062  51.832  1.00 62.88 ? 126 LYS   B CE   1 
ATOM   6656  N  NZ   . LYS   B 1 127 ? 23.227  34.427  51.519  1.00 66.07 ? 126 LYS   B NZ   1 
ATOM   6657  H  H    . LYS   B 1 127 ? 25.775  28.274  49.329  1.00 31.29 ? 126 LYS   B H    1 
ATOM   6658  H  HA   . LYS   B 1 127 ? 24.098  30.416  49.496  1.00 38.61 ? 126 LYS   B HA   1 
ATOM   6659  H  HB2  . LYS   B 1 127 ? 25.285  29.573  51.555  1.00 56.91 ? 126 LYS   B HB2  1 
ATOM   6660  H  HB3  . LYS   B 1 127 ? 26.409  30.550  51.000  1.00 56.91 ? 126 LYS   B HB3  1 
ATOM   6661  H  HG2  . LYS   B 1 127 ? 23.772  31.429  51.548  1.00 69.15 ? 126 LYS   B HG2  1 
ATOM   6662  H  HG3  . LYS   B 1 127 ? 24.966  31.609  52.581  1.00 69.15 ? 126 LYS   B HG3  1 
ATOM   6663  H  HD2  . LYS   B 1 127 ? 26.064  32.917  50.874  1.00 64.05 ? 126 LYS   B HD2  1 
ATOM   6664  H  HD3  . LYS   B 1 127 ? 24.665  32.934  50.119  1.00 64.05 ? 126 LYS   B HD3  1 
ATOM   6665  H  HE2  . LYS   B 1 127 ? 24.720  33.832  52.772  1.00 75.45 ? 126 LYS   B HE2  1 
ATOM   6666  H  HE3  . LYS   B 1 127 ? 25.221  34.827  51.639  1.00 75.45 ? 126 LYS   B HE3  1 
ATOM   6667  H  HZ1  . LYS   B 1 127 ? 23.076  34.343  50.646  1.00 79.28 ? 126 LYS   B HZ1  1 
ATOM   6668  H  HZ2  . LYS   B 1 127 ? 22.672  33.889  51.961  1.00 79.28 ? 126 LYS   B HZ2  1 
ATOM   6669  H  HZ3  . LYS   B 1 127 ? 23.068  35.268  51.760  1.00 79.28 ? 126 LYS   B HZ3  1 
ATOM   6670  N  N    . PHE   B 1 128 ? 25.334  31.661  47.788  1.00 27.57 ? 127 PHE   B N    1 
ATOM   6671  C  CA   . PHE   B 1 128 ? 26.115  32.383  46.816  1.00 26.79 ? 127 PHE   B CA   1 
ATOM   6672  C  C    . PHE   B 1 128 ? 26.880  33.502  47.507  1.00 32.01 ? 127 PHE   B C    1 
ATOM   6673  O  O    . PHE   B 1 128 ? 26.372  34.137  48.439  1.00 29.60 ? 127 PHE   B O    1 
ATOM   6674  C  CB   . PHE   B 1 128 ? 25.164  32.907  45.761  1.00 25.83 ? 127 PHE   B CB   1 
ATOM   6675  C  CG   . PHE   B 1 128 ? 24.747  31.840  44.773  1.00 25.39 ? 127 PHE   B CG   1 
ATOM   6676  C  CD1  . PHE   B 1 128 ? 25.689  31.211  43.973  1.00 28.57 ? 127 PHE   B CD1  1 
ATOM   6677  C  CD2  . PHE   B 1 128 ? 23.427  31.457  44.677  1.00 27.45 ? 127 PHE   B CD2  1 
ATOM   6678  C  CE1  . PHE   B 1 128 ? 25.300  30.251  43.072  1.00 30.11 ? 127 PHE   B CE1  1 
ATOM   6679  C  CE2  . PHE   B 1 128 ? 23.044  30.486  43.778  1.00 27.73 ? 127 PHE   B CE2  1 
ATOM   6680  C  CZ   . PHE   B 1 128 ? 23.982  29.887  42.994  1.00 27.33 ? 127 PHE   B CZ   1 
ATOM   6681  H  H    . PHE   B 1 128 ? 24.500  31.870  47.806  1.00 33.09 ? 127 PHE   B H    1 
ATOM   6682  H  HA   . PHE   B 1 128 ? 26.777  31.825  46.379  1.00 32.15 ? 127 PHE   B HA   1 
ATOM   6683  H  HB2  . PHE   B 1 128 ? 24.364  33.243  46.195  1.00 30.99 ? 127 PHE   B HB2  1 
ATOM   6684  H  HB3  . PHE   B 1 128 ? 25.599  33.620  45.268  1.00 30.99 ? 127 PHE   B HB3  1 
ATOM   6685  H  HD1  . PHE   B 1 128 ? 26.588  31.441  44.047  1.00 34.28 ? 127 PHE   B HD1  1 
ATOM   6686  H  HD2  . PHE   B 1 128 ? 22.790  31.856  45.225  1.00 32.94 ? 127 PHE   B HD2  1 
ATOM   6687  H  HE1  . PHE   B 1 128 ? 25.929  29.849  42.517  1.00 36.13 ? 127 PHE   B HE1  1 
ATOM   6688  H  HE2  . PHE   B 1 128 ? 22.149  30.242  43.706  1.00 33.27 ? 127 PHE   B HE2  1 
ATOM   6689  H  HZ   . PHE   B 1 128 ? 23.724  29.222  42.397  1.00 32.79 ? 127 PHE   B HZ   1 
ATOM   6690  N  N    . ASN   B 1 129 ? 28.100  33.748  47.036  1.00 28.78 ? 128 ASN   B N    1 
ATOM   6691  C  CA   . ASN   B 1 129 ? 28.860  34.844  47.611  1.00 34.26 ? 128 ASN   B CA   1 
ATOM   6692  C  C    . ASN   B 1 129 ? 28.540  36.196  46.983  1.00 31.18 ? 128 ASN   B C    1 
ATOM   6693  O  O    . ASN   B 1 129 ? 28.343  37.173  47.722  1.00 30.79 ? 128 ASN   B O    1 
ATOM   6694  C  CB   . ASN   B 1 129 ? 30.364  34.606  47.511  1.00 28.20 ? 128 ASN   B CB   1 
ATOM   6695  C  CG   . ASN   B 1 129 ? 30.806  33.381  48.284  1.00 36.76 ? 128 ASN   B CG   1 
ATOM   6696  O  OD1  . ASN   B 1 129 ? 30.233  33.053  49.324  1.00 41.04 ? 128 ASN   B OD1  1 
ATOM   6697  N  ND2  . ASN   B 1 129 ? 31.881  32.757  47.833  1.00 37.60 ? 128 ASN   B ND2  1 
ATOM   6698  H  H    . ASN   B 1 129 ? 28.492  33.309  46.409  1.00 34.53 ? 128 ASN   B H    1 
ATOM   6699  H  HA   . ASN   B 1 129 ? 28.593  34.883  48.543  1.00 41.11 ? 128 ASN   B HA   1 
ATOM   6700  H  HB2  . ASN   B 1 129 ? 30.604  34.477  46.579  1.00 33.84 ? 128 ASN   B HB2  1 
ATOM   6701  H  HB3  . ASN   B 1 129 ? 30.833  35.375  47.870  1.00 33.84 ? 128 ASN   B HB3  1 
ATOM   6702  H  HD21 . ASN   B 1 129 ? 32.288  33.052  47.135  1.00 45.13 ? 128 ASN   B HD21 1 
ATOM   6703  H  HD22 . ASN   B 1 129 ? 32.172  32.056  48.237  1.00 45.13 ? 128 ASN   B HD22 1 
ATOM   6704  N  N    . PRO   B 1 130 ? 28.493  36.318  45.660  1.00 29.45 ? 129 PRO   B N    1 
ATOM   6705  C  CA   . PRO   B 1 130 ? 28.170  37.618  45.072  1.00 27.68 ? 129 PRO   B CA   1 
ATOM   6706  C  C    . PRO   B 1 130 ? 26.762  38.018  45.460  1.00 28.60 ? 129 PRO   B C    1 
ATOM   6707  O  O    . PRO   B 1 130 ? 25.829  37.213  45.319  1.00 28.13 ? 129 PRO   B O    1 
ATOM   6708  C  CB   . PRO   B 1 130 ? 28.298  37.379  43.558  1.00 28.72 ? 129 PRO   B CB   1 
ATOM   6709  C  CG   . PRO   B 1 130 ? 29.116  36.090  43.436  1.00 29.23 ? 129 PRO   B CG   1 
ATOM   6710  C  CD   . PRO   B 1 130 ? 28.735  35.290  44.622  1.00 26.49 ? 129 PRO   B CD   1 
ATOM   6711  H  HA   . PRO   B 1 130 ? 28.805  38.302  45.337  1.00 33.22 ? 129 PRO   B HA   1 
ATOM   6712  H  HB2  . PRO   B 1 130 ? 27.418  37.271  43.165  1.00 34.46 ? 129 PRO   B HB2  1 
ATOM   6713  H  HB3  . PRO   B 1 130 ? 28.758  38.124  43.143  1.00 34.46 ? 129 PRO   B HB3  1 
ATOM   6714  H  HG2  . PRO   B 1 130 ? 28.885  35.628  42.615  1.00 35.07 ? 129 PRO   B HG2  1 
ATOM   6715  H  HG3  . PRO   B 1 130 ? 30.063  36.297  43.446  1.00 35.07 ? 129 PRO   B HG3  1 
ATOM   6716  H  HD2  . PRO   B 1 130 ? 27.930  34.777  44.448  1.00 31.79 ? 129 PRO   B HD2  1 
ATOM   6717  H  HD3  . PRO   B 1 130 ? 29.457  34.697  44.884  1.00 31.79 ? 129 PRO   B HD3  1 
ATOM   6718  N  N    . PRO   B 1 131 ? 26.587  39.204  46.064  1.00 25.04 ? 130 PRO   B N    1 
ATOM   6719  C  CA   . PRO   B 1 131 ? 25.227  39.669  46.378  1.00 28.83 ? 130 PRO   B CA   1 
ATOM   6720  C  C    . PRO   B 1 131 ? 24.274  39.607  45.197  1.00 22.04 ? 130 PRO   B C    1 
ATOM   6721  O  O    . PRO   B 1 131 ? 23.081  39.349  45.385  1.00 26.51 ? 130 PRO   B O    1 
ATOM   6722  C  CB   . PRO   B 1 131 ? 25.457  41.122  46.844  1.00 29.33 ? 130 PRO   B CB   1 
ATOM   6723  C  CG   . PRO   B 1 131 ? 26.818  41.092  47.449  1.00 29.02 ? 130 PRO   B CG   1 
ATOM   6724  C  CD   . PRO   B 1 131 ? 27.621  40.124  46.592  1.00 28.77 ? 130 PRO   B CD   1 
ATOM   6725  H  HA   . PRO   B 1 131 ? 24.861  39.149  47.111  1.00 34.60 ? 130 PRO   B HA   1 
ATOM   6726  H  HB2  . PRO   B 1 131 ? 25.423  41.726  46.086  1.00 35.19 ? 130 PRO   B HB2  1 
ATOM   6727  H  HB3  . PRO   B 1 131 ? 24.787  41.374  47.499  1.00 35.19 ? 130 PRO   B HB3  1 
ATOM   6728  H  HG2  . PRO   B 1 131 ? 27.208  41.980  47.425  1.00 34.82 ? 130 PRO   B HG2  1 
ATOM   6729  H  HG3  . PRO   B 1 131 ? 26.764  40.779  48.366  1.00 34.82 ? 130 PRO   B HG3  1 
ATOM   6730  H  HD2  . PRO   B 1 131 ? 28.069  40.591  45.870  1.00 34.53 ? 130 PRO   B HD2  1 
ATOM   6731  H  HD3  . PRO   B 1 131 ? 28.270  39.643  47.129  1.00 34.53 ? 130 PRO   B HD3  1 
ATOM   6732  N  N    . ALA   B 1 132 ? 24.761  39.845  43.985  1.00 23.17 ? 131 ALA   B N    1 
ATOM   6733  C  CA   . ALA   B 1 132 ? 23.881  39.766  42.828  1.00 25.63 ? 131 ALA   B CA   1 
ATOM   6734  C  C    . ALA   B 1 132 ? 23.201  38.404  42.741  1.00 24.56 ? 131 ALA   B C    1 
ATOM   6735  O  O    . ALA   B 1 132 ? 21.997  38.311  42.464  1.00 22.91 ? 131 ALA   B O    1 
ATOM   6736  C  CB   . ALA   B 1 132 ? 24.677  40.042  41.556  1.00 26.30 ? 131 ALA   B CB   1 
ATOM   6737  H  H    . ALA   B 1 132 ? 25.578  40.049  43.809  1.00 27.80 ? 131 ALA   B H    1 
ATOM   6738  H  HA   . ALA   B 1 132 ? 23.191  40.443  42.912  1.00 30.76 ? 131 ALA   B HA   1 
ATOM   6739  H  HB1  . ALA   B 1 132 ? 24.067  40.068  40.802  1.00 31.56 ? 131 ALA   B HB1  1 
ATOM   6740  H  HB2  . ALA   B 1 132 ? 25.129  40.896  41.645  1.00 31.56 ? 131 ALA   B HB2  1 
ATOM   6741  H  HB3  . ALA   B 1 132 ? 25.328  39.335  41.431  1.00 31.56 ? 131 ALA   B HB3  1 
ATOM   6742  N  N    . LEU   B 1 133 ? 23.963  37.333  42.945  1.00 24.65 ? 132 LEU   B N    1 
ATOM   6743  C  CA   . LEU   B 1 133 ? 23.374  35.993  42.863  1.00 29.03 ? 132 LEU   B CA   1 
ATOM   6744  C  C    . LEU   B 1 133 ? 22.496  35.707  44.065  1.00 28.62 ? 132 LEU   B C    1 
ATOM   6745  O  O    . LEU   B 1 133 ? 21.416  35.132  43.936  1.00 25.52 ? 132 LEU   B O    1 
ATOM   6746  C  CB   . LEU   B 1 133 ? 24.476  34.937  42.751  1.00 28.83 ? 132 LEU   B CB   1 
ATOM   6747  C  CG   . LEU   B 1 133 ? 25.159  34.885  41.396  1.00 24.66 ? 132 LEU   B CG   1 
ATOM   6748  C  CD1  . LEU   B 1 133 ? 26.412  34.011  41.402  1.00 27.74 ? 132 LEU   B CD1  1 
ATOM   6749  C  CD2  . LEU   B 1 133 ? 24.171  34.361  40.314  1.00 26.41 ? 132 LEU   B CD2  1 
ATOM   6750  H  H    . LEU   B 1 133 ? 24.803  37.349  43.128  1.00 29.58 ? 132 LEU   B H    1 
ATOM   6751  H  HA   . LEU   B 1 133 ? 22.825  35.945  42.064  1.00 34.84 ? 132 LEU   B HA   1 
ATOM   6752  H  HB2  . LEU   B 1 133 ? 25.155  35.129  43.416  1.00 34.60 ? 132 LEU   B HB2  1 
ATOM   6753  H  HB3  . LEU   B 1 133 ? 24.085  34.065  42.917  1.00 34.60 ? 132 LEU   B HB3  1 
ATOM   6754  H  HG   . LEU   B 1 133 ? 25.438  35.788  41.178  1.00 29.59 ? 132 LEU   B HG   1 
ATOM   6755  H  HD11 . LEU   B 1 133 ? 26.965  34.246  40.641  1.00 33.29 ? 132 LEU   B HD11 1 
ATOM   6756  H  HD12 . LEU   B 1 133 ? 26.901  34.166  42.226  1.00 33.29 ? 132 LEU   B HD12 1 
ATOM   6757  H  HD13 . LEU   B 1 133 ? 26.148  33.080  41.344  1.00 33.29 ? 132 LEU   B HD13 1 
ATOM   6758  H  HD21 . LEU   B 1 133 ? 24.662  33.831  39.667  1.00 31.69 ? 132 LEU   B HD21 1 
ATOM   6759  H  HD22 . LEU   B 1 133 ? 23.493  33.815  40.743  1.00 31.69 ? 132 LEU   B HD22 1 
ATOM   6760  H  HD23 . LEU   B 1 133 ? 23.754  35.118  39.873  1.00 31.69 ? 132 LEU   B HD23 1 
ATOM   6761  N  N    . GLN   B 1 134 ? 22.931  36.119  45.251  1.00 27.73 ? 133 GLN   B N    1 
ATOM   6762  C  CA   . GLN   B 1 134 ? 22.101  35.933  46.431  1.00 26.74 ? 133 GLN   B CA   1 
ATOM   6763  C  C    . GLN   B 1 134 ? 20.722  36.540  46.256  1.00 26.49 ? 133 GLN   B C    1 
ATOM   6764  O  O    . GLN   B 1 134 ? 19.702  35.894  46.517  1.00 31.20 ? 133 GLN   B O    1 
ATOM   6765  C  CB   . GLN   B 1 134 ? 22.776  36.582  47.646  1.00 36.26 ? 133 GLN   B CB   1 
ATOM   6766  C  CG   . GLN   B 1 134 ? 23.944  35.864  48.251  1.00 38.93 ? 133 GLN   B CG   1 
ATOM   6767  C  CD   . GLN   B 1 134 ? 24.496  36.671  49.436  1.00 47.24 ? 133 GLN   B CD   1 
ATOM   6768  O  OE1  . GLN   B 1 134 ? 23.739  37.092  50.308  1.00 51.60 ? 133 GLN   B OE1  1 
ATOM   6769  N  NE2  . GLN   B 1 134 ? 25.802  36.835  49.493  1.00 37.82 ? 133 GLN   B NE2  1 
ATOM   6770  H  H    . GLN   B 1 134 ? 23.688  36.502  45.396  1.00 33.28 ? 133 GLN   B H    1 
ATOM   6771  H  HA   . GLN   B 1 134 ? 22.005  34.979  46.577  1.00 32.09 ? 133 GLN   B HA   1 
ATOM   6772  H  HB2  . GLN   B 1 134 ? 23.093  37.458  47.377  1.00 43.51 ? 133 GLN   B HB2  1 
ATOM   6773  H  HB3  . GLN   B 1 134 ? 22.109  36.670  48.344  1.00 43.51 ? 133 GLN   B HB3  1 
ATOM   6774  H  HG2  . GLN   B 1 134 ? 23.663  34.992  48.571  1.00 46.72 ? 133 GLN   B HG2  1 
ATOM   6775  H  HG3  . GLN   B 1 134 ? 24.645  35.763  47.588  1.00 46.72 ? 133 GLN   B HG3  1 
ATOM   6776  H  HE21 . GLN   B 1 134 ? 26.305  36.496  48.883  1.00 45.38 ? 133 GLN   B HE21 1 
ATOM   6777  H  HE22 . GLN   B 1 134 ? 26.151  37.281  50.140  1.00 45.38 ? 133 GLN   B HE22 1 
ATOM   6778  N  N    . ASP   B 1 135 ? 20.680  37.817  45.879  1.00 26.69 ? 134 ASP   B N    1 
ATOM   6779  C  CA   . ASP   B 1 135 ? 19.410  38.518  45.754  1.00 26.80 ? 134 ASP   B CA   1 
ATOM   6780  C  C    . ASP   B 1 135 ? 18.534  37.853  44.693  1.00 28.31 ? 134 ASP   B C    1 
ATOM   6781  O  O    . ASP   B 1 135 ? 17.344  37.601  44.918  1.00 29.95 ? 134 ASP   B O    1 
ATOM   6782  C  CB   . ASP   B 1 135 ? 19.656  39.993  45.385  1.00 29.61 ? 134 ASP   B CB   1 
ATOM   6783  C  CG   . ASP   B 1 135 ? 20.347  40.784  46.491  1.00 30.87 ? 134 ASP   B CG   1 
ATOM   6784  O  OD1  . ASP   B 1 135 ? 20.459  40.275  47.609  1.00 30.50 ? 134 ASP   B OD1  1 
ATOM   6785  O  OD2  . ASP   B 1 135 ? 20.786  41.917  46.229  1.00 32.87 ? 134 ASP   B OD2  1 
ATOM   6786  H  H    . ASP   B 1 135 ? 21.369  38.296  45.692  1.00 32.03 ? 134 ASP   B H    1 
ATOM   6787  H  HA   . ASP   B 1 135 ? 18.948  38.489  46.606  1.00 32.16 ? 134 ASP   B HA   1 
ATOM   6788  H  HB2  . ASP   B 1 135 ? 20.219  40.029  44.596  1.00 35.53 ? 134 ASP   B HB2  1 
ATOM   6789  H  HB3  . ASP   B 1 135 ? 18.803  40.418  45.203  1.00 35.53 ? 134 ASP   B HB3  1 
ATOM   6790  N  N    . ALA   B 1 136 ? 19.120  37.566  43.524  1.00 28.04 ? 135 ALA   B N    1 
ATOM   6791  C  CA   . ALA   B 1 136 ? 18.353  37.003  42.411  1.00 26.34 ? 135 ALA   B CA   1 
ATOM   6792  C  C    . ALA   B 1 136 ? 17.875  35.586  42.703  1.00 23.78 ? 135 ALA   B C    1 
ATOM   6793  O  O    . ALA   B 1 136 ? 16.778  35.205  42.268  1.00 26.55 ? 135 ALA   B O    1 
ATOM   6794  C  CB   . ALA   B 1 136 ? 19.195  37.028  41.139  1.00 24.97 ? 135 ALA   B CB   1 
ATOM   6795  H  H    . ALA   B 1 136 ? 19.954  37.687  43.352  1.00 33.65 ? 135 ALA   B H    1 
ATOM   6796  H  HA   . ALA   B 1 136 ? 17.566  37.553  42.267  1.00 31.61 ? 135 ALA   B HA   1 
ATOM   6797  H  HB1  . ALA   B 1 136 ? 18.669  36.675  40.405  1.00 29.96 ? 135 ALA   B HB1  1 
ATOM   6798  H  HB2  . ALA   B 1 136 ? 19.454  37.943  40.950  1.00 29.96 ? 135 ALA   B HB2  1 
ATOM   6799  H  HB3  . ALA   B 1 136 ? 19.985  36.481  41.273  1.00 29.96 ? 135 ALA   B HB3  1 
ATOM   6800  N  N    . TYR   B 1 137 ? 18.657  34.808  43.453  1.00 24.58 ? 136 TYR   B N    1 
ATOM   6801  C  CA   . TYR   B 1 137 ? 18.253  33.449  43.839  1.00 25.58 ? 136 TYR   B CA   1 
ATOM   6802  C  C    . TYR   B 1 137 ? 17.024  33.481  44.734  1.00 34.45 ? 136 TYR   B C    1 
ATOM   6803  O  O    . TYR   B 1 137 ? 16.062  32.732  44.531  1.00 27.28 ? 136 TYR   B O    1 
ATOM   6804  C  CB   . TYR   B 1 137 ? 19.434  32.810  44.562  1.00 29.02 ? 136 TYR   B CB   1 
ATOM   6805  C  CG   . TYR   B 1 137 ? 19.459  31.341  44.943  1.00 32.60 ? 136 TYR   B CG   1 
ATOM   6806  C  CD1  . TYR   B 1 137 ? 18.642  30.376  44.348  1.00 41.05 ? 136 TYR   B CD1  1 
ATOM   6807  C  CD2  . TYR   B 1 137 ? 20.365  30.922  45.920  1.00 40.52 ? 136 TYR   B CD2  1 
ATOM   6808  C  CE1  . TYR   B 1 137 ? 18.748  29.019  44.737  1.00 39.59 ? 136 TYR   B CE1  1 
ATOM   6809  C  CE2  . TYR   B 1 137 ? 20.472  29.604  46.306  1.00 39.03 ? 136 TYR   B CE2  1 
ATOM   6810  C  CZ   . TYR   B 1 137 ? 19.684  28.652  45.706  1.00 40.88 ? 136 TYR   B CZ   1 
ATOM   6811  O  OH   . TYR   B 1 137 ? 19.851  27.354  46.143  1.00 38.61 ? 136 TYR   B OH   1 
ATOM   6812  H  H    . TYR   B 1 137 ? 19.429  35.040  43.753  1.00 29.50 ? 136 TYR   B H    1 
ATOM   6813  H  HA   . TYR   B 1 137 ? 18.026  32.921  43.057  1.00 30.70 ? 136 TYR   B HA   1 
ATOM   6814  H  HB2  . TYR   B 1 137 ? 20.211  32.942  43.996  1.00 34.82 ? 136 TYR   B HB2  1 
ATOM   6815  H  HB3  . TYR   B 1 137 ? 19.544  33.294  45.395  1.00 34.82 ? 136 TYR   B HB3  1 
ATOM   6816  H  HD1  . TYR   B 1 137 ? 18.027  30.625  43.696  1.00 49.26 ? 136 TYR   B HD1  1 
ATOM   6817  H  HD2  . TYR   B 1 137 ? 20.915  31.554  46.323  1.00 48.63 ? 136 TYR   B HD2  1 
ATOM   6818  H  HE1  . TYR   B 1 137 ? 18.198  28.376  44.350  1.00 47.51 ? 136 TYR   B HE1  1 
ATOM   6819  H  HE2  . TYR   B 1 137 ? 21.075  29.360  46.970  1.00 46.83 ? 136 TYR   B HE2  1 
ATOM   6820  H  HH   . TYR   B 1 137 ? 20.668  27.156  46.150  1.00 46.33 ? 136 TYR   B HH   1 
ATOM   6821  N  N    . TYR   B 1 138 ? 17.005  34.430  45.633  1.00 35.65 ? 137 TYR   B N    1 
ATOM   6822  C  CA   . TYR   B 1 138 ? 15.904  34.603  46.531  1.00 33.83 ? 137 TYR   B CA   1 
ATOM   6823  C  C    . TYR   B 1 138 ? 14.663  34.940  45.741  1.00 29.21 ? 137 TYR   B C    1 
ATOM   6824  O  O    . TYR   B 1 138 ? 13.634  34.391  45.935  1.00 36.46 ? 137 TYR   B O    1 
ATOM   6825  C  CB   . TYR   B 1 138 ? 16.253  35.744  47.478  1.00 42.14 ? 137 TYR   B CB   1 
ATOM   6826  H  H    . TYR   B 1 138 ? 17.637  35.002  45.744  1.00 42.78 ? 137 TYR   B H    1 
ATOM   6827  H  HA   . TYR   B 1 138 ? 15.751  33.784  47.047  1.00 40.60 ? 137 TYR   B HA   1 
ATOM   6828  N  N    . ARG   B 1 139 ? 14.786  35.867  44.834  1.00 29.02 ? 138 ARG   B N    1 
ATOM   6829  C  CA   . ARG   B 1 139 ? 13.652  36.214  43.991  1.00 33.81 ? 138 ARG   B CA   1 
ATOM   6830  C  C    . ARG   B 1 139 ? 13.227  35.026  43.131  1.00 37.18 ? 138 ARG   B C    1 
ATOM   6831  O  O    . ARG   B 1 139 ? 12.034  34.816  42.904  1.00 30.31 ? 138 ARG   B O    1 
ATOM   6832  C  CB   . ARG   B 1 139 ? 13.998  37.397  43.109  1.00 34.68 ? 138 ARG   B CB   1 
ATOM   6833  C  CG   . ARG   B 1 139 ? 14.187  38.698  43.855  1.00 45.50 ? 138 ARG   B CG   1 
ATOM   6834  C  CD   . ARG   B 1 139 ? 14.219  39.819  42.837  1.00 51.69 ? 138 ARG   B CD   1 
ATOM   6835  N  NE   . ARG   B 1 139 ? 12.999  39.861  42.035  1.00 60.34 ? 138 ARG   B NE   1 
ATOM   6836  C  CZ   . ARG   B 1 139 ? 12.791  40.698  41.031  1.00 56.51 ? 138 ARG   B CZ   1 
ATOM   6837  N  NH1  . ARG   B 1 139 ? 13.780  41.403  40.501  1.00 59.13 ? 138 ARG   B NH1  1 
ATOM   6838  N  NH2  . ARG   B 1 139 ? 11.562  40.826  40.541  1.00 57.64 ? 138 ARG   B NH2  1 
ATOM   6839  H  H    . ARG   B 1 139 ? 15.513  36.296  44.671  1.00 34.82 ? 138 ARG   B H    1 
ATOM   6840  H  HA   . ARG   B 1 139 ? 12.908  36.468  44.559  1.00 40.57 ? 138 ARG   B HA   1 
ATOM   6841  H  HB2  . ARG   B 1 139 ? 14.826  37.203  42.643  1.00 41.62 ? 138 ARG   B HB2  1 
ATOM   6842  H  HB3  . ARG   B 1 139 ? 13.280  37.526  42.470  1.00 41.62 ? 138 ARG   B HB3  1 
ATOM   6843  H  HG2  . ARG   B 1 139 ? 13.448  38.843  44.467  1.00 54.60 ? 138 ARG   B HG2  1 
ATOM   6844  H  HG3  . ARG   B 1 139 ? 15.025  38.685  44.343  1.00 54.60 ? 138 ARG   B HG3  1 
ATOM   6845  H  HD2  . ARG   B 1 139 ? 14.308  40.667  43.298  1.00 62.03 ? 138 ARG   B HD2  1 
ATOM   6846  H  HD3  . ARG   B 1 139 ? 14.971  39.686  42.238  1.00 62.03 ? 138 ARG   B HD3  1 
ATOM   6847  H  HE   . ARG   B 1 139 ? 12.374  39.303  42.229  1.00 72.41 ? 138 ARG   B HE   1 
ATOM   6848  H  HH11 . ARG   B 1 139 ? 14.579  41.321  40.809  1.00 70.95 ? 138 ARG   B HH11 1 
ATOM   6849  H  HH12 . ARG   B 1 139 ? 13.623  41.941  39.849  1.00 70.95 ? 138 ARG   B HH12 1 
ATOM   6850  H  HH21 . ARG   B 1 139 ? 10.916  40.368  40.876  1.00 69.16 ? 138 ARG   B HH21 1 
ATOM   6851  H  HH22 . ARG   B 1 139 ? 11.413  41.367  39.888  1.00 69.16 ? 138 ARG   B HH22 1 
ATOM   6852  N  N    . ALA   B 1 140 ? 14.195  34.263  42.613  1.00 28.76 ? 139 ALA   B N    1 
ATOM   6853  C  CA   . ALA   B 1 140 ? 13.848  33.129  41.756  1.00 33.96 ? 139 ALA   B CA   1 
ATOM   6854  C  C    . ALA   B 1 140 ? 13.088  32.053  42.530  1.00 32.43 ? 139 ALA   B C    1 
ATOM   6855  O  O    . ALA   B 1 140 ? 12.157  31.438  42.004  1.00 30.84 ? 139 ALA   B O    1 
ATOM   6856  C  CB   . ALA   B 1 140 ? 15.110  32.540  41.110  1.00 26.83 ? 139 ALA   B CB   1 
ATOM   6857  H  H    . ALA   B 1 140 ? 15.038  34.379  42.739  1.00 34.51 ? 139 ALA   B H    1 
ATOM   6858  H  HA   . ALA   B 1 140 ? 13.271  33.448  41.045  1.00 40.75 ? 139 ALA   B HA   1 
ATOM   6859  H  HB1  . ALA   B 1 140 ? 14.891  31.684  40.709  1.00 32.19 ? 139 ALA   B HB1  1 
ATOM   6860  H  HB2  . ALA   B 1 140 ? 15.432  33.152  40.429  1.00 32.19 ? 139 ALA   B HB2  1 
ATOM   6861  H  HB3  . ALA   B 1 140 ? 15.788  32.420  41.794  1.00 32.19 ? 139 ALA   B HB3  1 
ATOM   6862  N  N    . ARG   B 1 141 ? 13.484  31.805  43.773  1.00 30.72 ? 140 ARG   B N    1 
ATOM   6863  C  CA   . ARG   B 1 141 ? 12.827  30.781  44.585  1.00 34.93 ? 140 ARG   B CA   1 
ATOM   6864  C  C    . ARG   B 1 141 ? 11.354  31.106  44.817  1.00 34.85 ? 140 ARG   B C    1 
ATOM   6865  O  O    . ARG   B 1 141 ? 10.522  30.213  44.973  1.00 41.12 ? 140 ARG   B O    1 
ATOM   6866  C  CB   . ARG   B 1 141 ? 13.538  30.638  45.931  1.00 33.66 ? 140 ARG   B CB   1 
ATOM   6867  C  CG   . ARG   B 1 141 ? 14.012  29.225  46.231  1.00 43.38 ? 140 ARG   B CG   1 
ATOM   6868  C  CD   . ARG   B 1 141 ? 14.274  29.029  47.716  1.00 50.41 ? 140 ARG   B CD   1 
ATOM   6869  N  NE   . ARG   B 1 141 ? 15.701  28.941  48.010  1.00 55.11 ? 140 ARG   B NE   1 
ATOM   6870  C  CZ   . ARG   B 1 141 ? 16.303  27.850  48.472  1.00 43.91 ? 140 ARG   B CZ   1 
ATOM   6871  N  NH1  . ARG   B 1 141 ? 15.601  26.747  48.696  1.00 41.11 ? 140 ARG   B NH1  1 
ATOM   6872  N  NH2  . ARG   B 1 141 ? 17.607  27.861  48.711  1.00 51.75 ? 140 ARG   B NH2  1 
ATOM   6873  H  H    . ARG   B 1 141 ? 14.128  32.214  44.171  1.00 36.86 ? 140 ARG   B H    1 
ATOM   6874  H  HA   . ARG   B 1 141 ? 12.879  29.921  44.119  1.00 41.92 ? 140 ARG   B HA   1 
ATOM   6875  H  HB2  . ARG   B 1 141 ? 14.314  31.219  45.938  1.00 40.39 ? 140 ARG   B HB2  1 
ATOM   6876  H  HB3  . ARG   B 1 141 ? 12.925  30.900  46.635  1.00 40.39 ? 140 ARG   B HB3  1 
ATOM   6877  H  HG2  . ARG   B 1 141 ? 13.329  28.594  45.957  1.00 52.05 ? 140 ARG   B HG2  1 
ATOM   6878  H  HG3  . ARG   B 1 141 ? 14.838  29.057  45.751  1.00 52.05 ? 140 ARG   B HG3  1 
ATOM   6879  H  HD2  . ARG   B 1 141 ? 13.910  29.783  48.206  1.00 60.49 ? 140 ARG   B HD2  1 
ATOM   6880  H  HD3  . ARG   B 1 141 ? 13.853  28.205  48.007  1.00 60.49 ? 140 ARG   B HD3  1 
ATOM   6881  H  HE   . ARG   B 1 141 ? 16.223  29.756  47.959  1.00 66.13 ? 140 ARG   B HE   1 
ATOM   6882  H  HH11 . ARG   B 1 141 ? 14.755  26.736  48.543  1.00 49.33 ? 140 ARG   B HH11 1 
ATOM   6883  H  HH12 . ARG   B 1 141 ? 15.993  26.043  48.996  1.00 49.33 ? 140 ARG   B HH12 1 
ATOM   6884  H  HH21 . ARG   B 1 141 ? 17.996  27.155  49.010  1.00 62.10 ? 140 ARG   B HH21 1 
ATOM   6885  H  HH22 . ARG   B 1 141 ? 18.064  28.575  48.566  1.00 62.10 ? 140 ARG   B HH22 1 
ATOM   6886  N  N    . ALA   B 1 142 ? 11.049  32.397  44.833  1.00 37.83 ? 141 ALA   B N    1 
ATOM   6887  C  CA   . ALA   B 1 142 ? 9.708   32.892  45.062  1.00 43.53 ? 141 ALA   B CA   1 
ATOM   6888  C  C    . ALA   B 1 142 ? 8.903   33.006  43.780  1.00 42.71 ? 141 ALA   B C    1 
ATOM   6889  O  O    . ALA   B 1 142 ? 7.724   33.361  43.832  1.00 40.42 ? 141 ALA   B O    1 
ATOM   6890  C  CB   . ALA   B 1 142 ? 9.757   34.266  45.749  1.00 43.14 ? 141 ALA   B CB   1 
ATOM   6891  H  H    . ALA   B 1 142 ? 11.627  33.024  44.723  1.00 45.39 ? 141 ALA   B H    1 
ATOM   6892  H  HA   . ALA   B 1 142 ? 9.248   32.280  45.658  1.00 52.23 ? 141 ALA   B HA   1 
ATOM   6893  H  HB1  . ALA   B 1 142 ? 8.910   34.427  46.194  1.00 51.77 ? 141 ALA   B HB1  1 
ATOM   6894  H  HB2  . ALA   B 1 142 ? 10.478  34.269  46.398  1.00 51.77 ? 141 ALA   B HB2  1 
ATOM   6895  H  HB3  . ALA   B 1 142 ? 9.913   34.949  45.078  1.00 51.77 ? 141 ALA   B HB3  1 
ATOM   6896  N  N    . GLY   B 1 143 ? 9.507   32.711  42.629  1.00 38.26 ? 142 GLY   B N    1 
ATOM   6897  C  CA   . GLY   B 1 143 ? 8.788   32.673  41.369  1.00 32.40 ? 142 GLY   B CA   1 
ATOM   6898  C  C    . GLY   B 1 143 ? 9.233   33.667  40.324  1.00 34.90 ? 142 GLY   B C    1 
ATOM   6899  O  O    . GLY   B 1 143 ? 8.799   33.543  39.171  1.00 36.47 ? 142 GLY   B O    1 
ATOM   6900  H  H    . GLY   B 1 143 ? 10.344  32.526  42.557  1.00 45.91 ? 142 GLY   B H    1 
ATOM   6901  H  HA2  . GLY   B 1 143 ? 8.885   31.786  40.988  1.00 38.88 ? 142 GLY   B HA2  1 
ATOM   6902  H  HA3  . GLY   B 1 143 ? 7.849   32.839  41.547  1.00 38.88 ? 142 GLY   B HA3  1 
ATOM   6903  N  N    . GLU   B 1 144 ? 10.072  34.650  40.649  1.00 32.92 ? 143 GLU   B N    1 
ATOM   6904  C  CA   . GLU   B 1 144 ? 10.512  35.675  39.693  1.00 32.83 ? 143 GLU   B CA   1 
ATOM   6905  C  C    . GLU   B 1 144 ? 11.980  35.414  39.347  1.00 31.26 ? 143 GLU   B C    1 
ATOM   6906  O  O    . GLU   B 1 144 ? 12.899  35.975  39.958  1.00 29.83 ? 143 GLU   B O    1 
ATOM   6907  C  CB   . GLU   B 1 144 ? 10.320  37.097  40.256  1.00 42.12 ? 143 GLU   B CB   1 
ATOM   6908  C  CG   . GLU   B 1 144 ? 8.959   37.718  39.979  1.00 47.96 ? 143 GLU   B CG   1 
ATOM   6909  C  CD   . GLU   B 1 144 ? 8.776   39.059  40.680  1.00 70.24 ? 143 GLU   B CD   1 
ATOM   6910  O  OE1  . GLU   B 1 144 ? 9.569   39.373  41.602  1.00 62.99 ? 143 GLU   B OE1  1 
ATOM   6911  O  OE2  . GLU   B 1 144 ? 7.860   39.816  40.281  1.00 71.77 ? 143 GLU   B OE2  1 
ATOM   6912  H  H    . GLU   B 1 144 ? 10.409  34.748  41.434  1.00 39.50 ? 143 GLU   B H    1 
ATOM   6913  H  HA   . GLU   B 1 144 ? 9.980   35.586  38.887  1.00 39.40 ? 143 GLU   B HA   1 
ATOM   6914  H  HB2  . GLU   B 1 144 ? 10.435  37.065  41.219  1.00 50.55 ? 143 GLU   B HB2  1 
ATOM   6915  H  HB3  . GLU   B 1 144 ? 10.991  37.676  39.862  1.00 50.55 ? 143 GLU   B HB3  1 
ATOM   6916  H  HG2  . GLU   B 1 144 ? 8.866   37.863  39.024  1.00 57.55 ? 143 GLU   B HG2  1 
ATOM   6917  H  HG3  . GLU   B 1 144 ? 8.266   37.117  40.293  1.00 57.55 ? 143 GLU   B HG3  1 
ATOM   6918  N  N    . ALA   B 1 145 ? 12.204  34.565  38.349  1.00 27.73 ? 144 ALA   B N    1 
ATOM   6919  C  CA   . ALA   B 1 145 ? 13.529  34.015  38.095  1.00 23.73 ? 144 ALA   B CA   1 
ATOM   6920  C  C    . ALA   B 1 145 ? 14.269  34.660  36.920  1.00 25.49 ? 144 ALA   B C    1 
ATOM   6921  O  O    . ALA   B 1 145 ? 15.393  34.244  36.623  1.00 25.33 ? 144 ALA   B O    1 
ATOM   6922  C  CB   . ALA   B 1 145 ? 13.401  32.502  37.869  1.00 28.18 ? 144 ALA   B CB   1 
ATOM   6923  H  H    . ALA   B 1 145 ? 11.599  34.292  37.802  1.00 33.27 ? 144 ALA   B H    1 
ATOM   6924  H  HA   . ALA   B 1 145 ? 14.082  34.174  38.876  1.00 28.48 ? 144 ALA   B HA   1 
ATOM   6925  H  HB1  . ALA   B 1 145 ? 14.129  32.052  38.324  1.00 33.82 ? 144 ALA   B HB1  1 
ATOM   6926  H  HB2  . ALA   B 1 145 ? 12.551  32.200  38.225  1.00 33.82 ? 144 ALA   B HB2  1 
ATOM   6927  H  HB3  . ALA   B 1 145 ? 13.443  32.320  36.917  1.00 33.82 ? 144 ALA   B HB3  1 
ATOM   6928  N  N    . ALA   B 1 146 ? 13.714  35.704  36.287  1.00 25.07 ? 145 ALA   B N    1 
ATOM   6929  C  CA   . ALA   B 1 146 ? 14.332  36.262  35.085  1.00 24.06 ? 145 ALA   B CA   1 
ATOM   6930  C  C    . ALA   B 1 146 ? 15.727  36.816  35.357  1.00 24.20 ? 145 ALA   B C    1 
ATOM   6931  O  O    . ALA   B 1 146 ? 16.657  36.578  34.584  1.00 23.38 ? 145 ALA   B O    1 
ATOM   6932  C  CB   . ALA   B 1 146 ? 13.420  37.331  34.470  1.00 25.58 ? 145 ALA   B CB   1 
ATOM   6933  H  H    . ALA   B 1 146 ? 12.990  36.099  36.532  1.00 30.08 ? 145 ALA   B H    1 
ATOM   6934  H  HA   . ALA   B 1 146 ? 14.434  35.548  34.436  1.00 28.87 ? 145 ALA   B HA   1 
ATOM   6935  H  HB1  . ALA   B 1 146 ? 13.854  37.704  33.687  1.00 30.69 ? 145 ALA   B HB1  1 
ATOM   6936  H  HB2  . ALA   B 1 146 ? 12.578  36.921  34.218  1.00 30.69 ? 145 ALA   B HB2  1 
ATOM   6937  H  HB3  . ALA   B 1 146 ? 13.265  38.028  35.126  1.00 30.69 ? 145 ALA   B HB3  1 
ATOM   6938  N  N    . ASN   B 1 147 ? 15.916  37.542  36.461  1.00 24.31 ? 146 ASN   B N    1 
ATOM   6939  C  CA   . ASN   B 1 147 ? 17.246  38.083  36.722  1.00 23.93 ? 146 ASN   B CA   1 
ATOM   6940  C  C    . ASN   B 1 147 ? 18.261  36.995  37.034  1.00 20.87 ? 146 ASN   B C    1 
ATOM   6941  O  O    . ASN   B 1 147 ? 19.427  37.097  36.632  1.00 24.11 ? 146 ASN   B O    1 
ATOM   6942  C  CB   . ASN   B 1 147 ? 17.180  39.087  37.871  1.00 25.12 ? 146 ASN   B CB   1 
ATOM   6943  C  CG   . ASN   B 1 147 ? 16.789  40.457  37.391  1.00 30.76 ? 146 ASN   B CG   1 
ATOM   6944  O  OD1  . ASN   B 1 147 ? 17.643  41.275  37.044  1.00 37.19 ? 146 ASN   B OD1  1 
ATOM   6945  N  ND2  . ASN   B 1 147 ? 15.506  40.675  37.269  1.00 32.86 ? 146 ASN   B ND2  1 
ATOM   6946  H  H    . ASN   B 1 147 ? 15.316  37.727  37.049  1.00 29.18 ? 146 ASN   B H    1 
ATOM   6947  H  HA   . ASN   B 1 147 ? 17.548  38.541  35.922  1.00 28.71 ? 146 ASN   B HA   1 
ATOM   6948  H  HB2  . ASN   B 1 147 ? 16.519  38.792  38.516  1.00 30.14 ? 146 ASN   B HB2  1 
ATOM   6949  H  HB3  . ASN   B 1 147 ? 18.051  39.150  38.292  1.00 30.14 ? 146 ASN   B HB3  1 
ATOM   6950  H  HD21 . ASN   B 1 147 ? 14.944  40.053  37.459  1.00 39.43 ? 146 ASN   B HD21 1 
ATOM   6951  H  HD22 . ASN   B 1 147 ? 15.224  41.441  36.998  1.00 39.43 ? 146 ASN   B HD22 1 
ATOM   6952  N  N    . PHE   B 1 148 ? 17.852  35.989  37.799  1.00 22.62 ? 147 PHE   B N    1 
ATOM   6953  C  CA   . PHE   B 1 148 ? 18.734  34.871  38.133  1.00 21.18 ? 147 PHE   B CA   1 
ATOM   6954  C  C    . PHE   B 1 148 ? 19.208  34.148  36.872  1.00 20.76 ? 147 PHE   B C    1 
ATOM   6955  O  O    . PHE   B 1 148 ? 20.408  33.900  36.695  1.00 20.28 ? 147 PHE   B O    1 
ATOM   6956  C  CB   . PHE   B 1 148 ? 17.984  33.936  39.083  1.00 25.10 ? 147 PHE   B CB   1 
ATOM   6957  C  CG   . PHE   B 1 148 ? 18.837  32.904  39.751  1.00 22.83 ? 147 PHE   B CG   1 
ATOM   6958  C  CD1  . PHE   B 1 148 ? 20.000  33.259  40.427  1.00 24.41 ? 147 PHE   B CD1  1 
ATOM   6959  C  CD2  . PHE   B 1 148 ? 18.462  31.559  39.721  1.00 26.11 ? 147 PHE   B CD2  1 
ATOM   6960  C  CE1  . PHE   B 1 148 ? 20.779  32.294  41.053  1.00 24.72 ? 147 PHE   B CE1  1 
ATOM   6961  C  CE2  . PHE   B 1 148 ? 19.224  30.600  40.353  1.00 27.71 ? 147 PHE   B CE2  1 
ATOM   6962  C  CZ   . PHE   B 1 148 ? 20.390  30.972  41.021  1.00 28.09 ? 147 PHE   B CZ   1 
ATOM   6963  H  H    . PHE   B 1 148 ? 17.065  35.926  38.140  1.00 27.14 ? 147 PHE   B H    1 
ATOM   6964  H  HA   . PHE   B 1 148 ? 19.531  35.190  38.585  1.00 25.41 ? 147 PHE   B HA   1 
ATOM   6965  H  HB2  . PHE   B 1 148 ? 17.573  34.471  39.780  1.00 30.12 ? 147 PHE   B HB2  1 
ATOM   6966  H  HB3  . PHE   B 1 148 ? 17.301  33.468  38.578  1.00 30.12 ? 147 PHE   B HB3  1 
ATOM   6967  H  HD1  . PHE   B 1 148 ? 20.259  34.152  40.461  1.00 29.29 ? 147 PHE   B HD1  1 
ATOM   6968  H  HD2  . PHE   B 1 148 ? 17.689  31.308  39.269  1.00 31.34 ? 147 PHE   B HD2  1 
ATOM   6969  H  HE1  . PHE   B 1 148 ? 21.562  32.539  41.493  1.00 29.66 ? 147 PHE   B HE1  1 
ATOM   6970  H  HE2  . PHE   B 1 148 ? 18.962  29.708  40.333  1.00 33.25 ? 147 PHE   B HE2  1 
ATOM   6971  H  HZ   . PHE   B 1 148 ? 20.906  30.326  41.446  1.00 33.71 ? 147 PHE   B HZ   1 
ATOM   6972  N  N    . CYS   B 1 149 ? 18.278  33.852  35.963  1.00 23.47 ? 148 CYS   B N    1 
ATOM   6973  C  CA   . CYS   B 1 149 ? 18.652  33.193  34.715  1.00 22.89 ? 148 CYS   B CA   1 
ATOM   6974  C  C    . CYS   B 1 149 ? 19.586  34.064  33.893  1.00 21.79 ? 148 CYS   B C    1 
ATOM   6975  O  O    . CYS   B 1 149 ? 20.564  33.574  33.314  1.00 23.48 ? 148 CYS   B O    1 
ATOM   6976  C  CB   . CYS   B 1 149 ? 17.390  32.826  33.919  1.00 22.17 ? 148 CYS   B CB   1 
ATOM   6977  S  SG   . CYS   B 1 149 ? 16.456  31.559  34.703  1.00 27.50 ? 148 CYS   B SG   1 
ATOM   6978  H  H    . CYS   B 1 149 ? 17.438  34.020  36.043  1.00 28.16 ? 148 CYS   B H    1 
ATOM   6979  H  HA   . CYS   B 1 149 ? 19.123  32.369  34.918  1.00 27.47 ? 148 CYS   B HA   1 
ATOM   6980  H  HB2  . CYS   B 1 149 ? 16.826  33.611  33.837  1.00 26.61 ? 148 CYS   B HB2  1 
ATOM   6981  H  HB3  . CYS   B 1 149 ? 17.650  32.510  33.039  1.00 26.61 ? 148 CYS   B HB3  1 
ATOM   6982  H  HG   . CYS   B 1 149 ? 15.530  31.264  33.999  1.00 33.00 ? 148 CYS   B HG   1 
ATOM   6983  N  N    . ALA   B 1 150 ? 19.331  35.373  33.850  1.00 21.33 ? 149 ALA   B N    1 
ATOM   6984  C  CA   . ALA   B 1 150 ? 20.210  36.236  33.077  1.00 22.24 ? 149 ALA   B CA   1 
ATOM   6985  C  C    . ALA   B 1 150 ? 21.599  36.309  33.704  1.00 23.58 ? 149 ALA   B C    1 
ATOM   6986  O  O    . ALA   B 1 150 ? 22.603  36.371  32.989  1.00 23.74 ? 149 ALA   B O    1 
ATOM   6987  C  CB   . ALA   B 1 150 ? 19.577  37.626  32.917  1.00 22.52 ? 149 ALA   B CB   1 
ATOM   6988  H  H    . ALA   B 1 150 ? 18.678  35.768  34.246  1.00 25.60 ? 149 ALA   B H    1 
ATOM   6989  H  HA   . ALA   B 1 150 ? 20.318  35.871  32.185  1.00 26.68 ? 149 ALA   B HA   1 
ATOM   6990  H  HB1  . ALA   B 1 150 ? 20.255  38.249  32.611  1.00 27.02 ? 149 ALA   B HB1  1 
ATOM   6991  H  HB2  . ALA   B 1 150 ? 18.859  37.573  32.267  1.00 27.02 ? 149 ALA   B HB2  1 
ATOM   6992  H  HB3  . ALA   B 1 150 ? 19.227  37.914  33.775  1.00 27.02 ? 149 ALA   B HB3  1 
ATOM   6993  N  N    . LEU   B 1 151 ? 21.682  36.325  35.039  1.00 23.74 ? 150 LEU   B N    1 
ATOM   6994  C  CA   . LEU   B 1 151 ? 22.988  36.320  35.686  1.00 23.11 ? 150 LEU   B CA   1 
ATOM   6995  C  C    . LEU   B 1 151 ? 23.733  35.005  35.436  1.00 25.26 ? 150 LEU   B C    1 
ATOM   6996  O  O    . LEU   B 1 151 ? 24.950  35.008  35.182  1.00 25.84 ? 150 LEU   B O    1 
ATOM   6997  C  CB   . LEU   B 1 151 ? 22.805  36.555  37.175  1.00 22.22 ? 150 LEU   B CB   1 
ATOM   6998  C  CG   . LEU   B 1 151 ? 22.563  38.015  37.543  1.00 21.90 ? 150 LEU   B CG   1 
ATOM   6999  C  CD1  . LEU   B 1 151 ? 22.058  38.027  38.979  1.00 27.62 ? 150 LEU   B CD1  1 
ATOM   7000  C  CD2  . LEU   B 1 151 ? 23.789  38.888  37.390  1.00 30.70 ? 150 LEU   B CD2  1 
ATOM   7001  H  H    . LEU   B 1 151 ? 21.010  36.338  35.577  1.00 28.49 ? 150 LEU   B H    1 
ATOM   7002  H  HA   . LEU   B 1 151 ? 23.529  37.037  35.320  1.00 27.74 ? 150 LEU   B HA   1 
ATOM   7003  H  HB2  . LEU   B 1 151 ? 22.040  36.042  37.479  1.00 26.67 ? 150 LEU   B HB2  1 
ATOM   7004  H  HB3  . LEU   B 1 151 ? 23.606  36.262  37.637  1.00 26.67 ? 150 LEU   B HB3  1 
ATOM   7005  H  HG   . LEU   B 1 151 ? 21.915  38.403  36.936  1.00 26.29 ? 150 LEU   B HG   1 
ATOM   7006  H  HD11 . LEU   B 1 151 ? 22.161  38.920  39.342  1.00 33.15 ? 150 LEU   B HD11 1 
ATOM   7007  H  HD12 . LEU   B 1 151 ? 21.122  37.773  38.986  1.00 33.15 ? 150 LEU   B HD12 1 
ATOM   7008  H  HD13 . LEU   B 1 151 ? 22.577  37.395  39.502  1.00 33.15 ? 150 LEU   B HD13 1 
ATOM   7009  H  HD21 . LEU   B 1 151 ? 23.635  39.730  37.846  1.00 36.84 ? 150 LEU   B HD21 1 
ATOM   7010  H  HD22 . LEU   B 1 151 ? 24.551  38.434  37.780  1.00 36.84 ? 150 LEU   B HD22 1 
ATOM   7011  H  HD23 . LEU   B 1 151 ? 23.946  39.048  36.446  1.00 36.84 ? 150 LEU   B HD23 1 
ATOM   7012  N  N    . ILE   B 1 152 ? 23.024  33.874  35.496  1.00 25.60 ? 151 ILE   B N    1 
ATOM   7013  C  CA   . ILE   B 1 152 ? 23.669  32.589  35.227  1.00 24.36 ? 151 ILE   B CA   1 
ATOM   7014  C  C    . ILE   B 1 152 ? 24.285  32.606  33.841  1.00 20.52 ? 151 ILE   B C    1 
ATOM   7015  O  O    . ILE   B 1 152 ? 25.447  32.235  33.658  1.00 25.35 ? 151 ILE   B O    1 
ATOM   7016  C  CB   . ILE   B 1 152 ? 22.679  31.420  35.380  1.00 25.17 ? 151 ILE   B CB   1 
ATOM   7017  C  CG1  . ILE   B 1 152 ? 22.321  31.172  36.843  1.00 27.80 ? 151 ILE   B CG1  1 
ATOM   7018  C  CG2  . ILE   B 1 152 ? 23.259  30.129  34.821  1.00 26.44 ? 151 ILE   B CG2  1 
ATOM   7019  C  CD1  . ILE   B 1 152 ? 21.028  30.412  37.012  1.00 29.04 ? 151 ILE   B CD1  1 
ATOM   7020  H  H    . ILE   B 1 152 ? 22.186  33.826  35.686  1.00 30.72 ? 151 ILE   B H    1 
ATOM   7021  H  HA   . ILE   B 1 152 ? 24.371  32.462  35.884  1.00 29.24 ? 151 ILE   B HA   1 
ATOM   7022  H  HB   . ILE   B 1 152 ? 21.884  31.675  34.885  1.00 30.21 ? 151 ILE   B HB   1 
ATOM   7023  H  HG12 . ILE   B 1 152 ? 23.029  30.654  37.257  1.00 33.36 ? 151 ILE   B HG12 1 
ATOM   7024  H  HG13 . ILE   B 1 152 ? 22.228  32.026  37.293  1.00 33.36 ? 151 ILE   B HG13 1 
ATOM   7025  H  HG21 . ILE   B 1 152 ? 22.777  29.376  35.197  1.00 31.73 ? 151 ILE   B HG21 1 
ATOM   7026  H  HG22 . ILE   B 1 152 ? 23.165  30.132  33.855  1.00 31.73 ? 151 ILE   B HG22 1 
ATOM   7027  H  HG23 . ILE   B 1 152 ? 24.197  30.074  35.062  1.00 31.73 ? 151 ILE   B HG23 1 
ATOM   7028  H  HD11 . ILE   B 1 152 ? 21.128  29.776  37.738  1.00 34.85 ? 151 ILE   B HD11 1 
ATOM   7029  H  HD12 . ILE   B 1 152 ? 20.317  31.040  37.218  1.00 34.85 ? 151 ILE   B HD12 1 
ATOM   7030  H  HD13 . ILE   B 1 152 ? 20.826  29.944  36.187  1.00 34.85 ? 151 ILE   B HD13 1 
ATOM   7031  N  N    . LEU   B 1 153 ? 23.531  33.085  32.856  1.00 22.48 ? 152 LEU   B N    1 
ATOM   7032  C  CA   . LEU   B 1 153 ? 24.059  33.188  31.493  1.00 24.74 ? 152 LEU   B CA   1 
ATOM   7033  C  C    . LEU   B 1 153 ? 25.309  34.063  31.454  1.00 28.57 ? 152 LEU   B C    1 
ATOM   7034  O  O    . LEU   B 1 153 ? 26.329  33.702  30.844  1.00 27.66 ? 152 LEU   B O    1 
ATOM   7035  C  CB   . LEU   B 1 153 ? 22.983  33.753  30.564  1.00 25.75 ? 152 LEU   B CB   1 
ATOM   7036  C  CG   . LEU   B 1 153 ? 21.789  32.833  30.272  1.00 27.70 ? 152 LEU   B CG   1 
ATOM   7037  C  CD1  . LEU   B 1 153 ? 20.550  33.566  29.804  1.00 28.46 ? 152 LEU   B CD1  1 
ATOM   7038  C  CD2  . LEU   B 1 153 ? 22.197  31.782  29.224  1.00 30.92 ? 152 LEU   B CD2  1 
ATOM   7039  H  H    . LEU   B 1 153 ? 22.719  33.355  32.946  1.00 26.98 ? 152 LEU   B H    1 
ATOM   7040  H  HA   . LEU   B 1 153 ? 24.299  32.302  31.180  1.00 29.69 ? 152 LEU   B HA   1 
ATOM   7041  H  HB2  . LEU   B 1 153 ? 22.629  34.561  30.968  1.00 30.90 ? 152 LEU   B HB2  1 
ATOM   7042  H  HB3  . LEU   B 1 153 ? 23.399  33.962  29.713  1.00 30.90 ? 152 LEU   B HB3  1 
ATOM   7043  H  HG   . LEU   B 1 153 ? 21.546  32.406  31.108  1.00 33.25 ? 152 LEU   B HG   1 
ATOM   7044  H  HD11 . LEU   B 1 153 ? 19.783  32.978  29.893  1.00 34.15 ? 152 LEU   B HD11 1 
ATOM   7045  H  HD12 . LEU   B 1 153 ? 20.425  34.357  30.352  1.00 34.15 ? 152 LEU   B HD12 1 
ATOM   7046  H  HD13 . LEU   B 1 153 ? 20.665  33.822  28.876  1.00 34.15 ? 152 LEU   B HD13 1 
ATOM   7047  H  HD21 . LEU   B 1 153 ? 21.446  31.190  29.062  1.00 37.10 ? 152 LEU   B HD21 1 
ATOM   7048  H  HD22 . LEU   B 1 153 ? 22.445  32.235  28.403  1.00 37.10 ? 152 LEU   B HD22 1 
ATOM   7049  H  HD23 . LEU   B 1 153 ? 22.952  31.275  29.563  1.00 37.10 ? 152 LEU   B HD23 1 
ATOM   7050  N  N    . ALA   B 1 154 ? 25.260  35.222  32.124  1.00 23.76 ? 153 ALA   B N    1 
ATOM   7051  C  CA   . ALA   B 1 154 ? 26.409  36.124  32.105  1.00 26.39 ? 153 ALA   B CA   1 
ATOM   7052  C  C    . ALA   B 1 154 ? 27.609  35.513  32.824  1.00 22.96 ? 153 ALA   B C    1 
ATOM   7053  O  O    . ALA   B 1 154 ? 28.733  35.552  32.314  1.00 30.07 ? 153 ALA   B O    1 
ATOM   7054  C  CB   . ALA   B 1 154 ? 26.049  37.460  32.772  1.00 25.38 ? 153 ALA   B CB   1 
ATOM   7055  H  H    . ALA   B 1 154 ? 24.589  35.499  32.585  1.00 28.51 ? 153 ALA   B H    1 
ATOM   7056  H  HA   . ALA   B 1 154 ? 26.644  36.286  31.179  1.00 31.67 ? 153 ALA   B HA   1 
ATOM   7057  H  HB1  . ALA   B 1 154 ? 26.773  38.090  32.629  1.00 30.45 ? 153 ALA   B HB1  1 
ATOM   7058  H  HB2  . ALA   B 1 154 ? 25.231  37.801  32.377  1.00 30.45 ? 153 ALA   B HB2  1 
ATOM   7059  H  HB3  . ALA   B 1 154 ? 25.921  37.314  33.723  1.00 30.45 ? 153 ALA   B HB3  1 
ATOM   7060  N  N    . TYR   B 1 155 ? 27.400  34.978  34.026  1.00 23.85 ? 154 TYR   B N    1 
ATOM   7061  C  CA   . TYR   B 1 155 ? 28.509  34.351  34.743  1.00 24.08 ? 154 TYR   B CA   1 
ATOM   7062  C  C    . TYR   B 1 155 ? 29.113  33.216  33.930  1.00 29.64 ? 154 TYR   B C    1 
ATOM   7063  O  O    . TYR   B 1 155 ? 30.338  33.066  33.880  1.00 30.50 ? 154 TYR   B O    1 
ATOM   7064  C  CB   . TYR   B 1 155 ? 28.050  33.834  36.096  1.00 28.26 ? 154 TYR   B CB   1 
ATOM   7065  C  CG   . TYR   B 1 155 ? 28.009  34.925  37.142  1.00 26.42 ? 154 TYR   B CG   1 
ATOM   7066  C  CD1  . TYR   B 1 155 ? 29.175  35.525  37.607  1.00 29.88 ? 154 TYR   B CD1  1 
ATOM   7067  C  CD2  . TYR   B 1 155 ? 26.791  35.369  37.646  1.00 28.35 ? 154 TYR   B CD2  1 
ATOM   7068  C  CE1  . TYR   B 1 155 ? 29.119  36.534  38.557  1.00 29.86 ? 154 TYR   B CE1  1 
ATOM   7069  C  CE2  . TYR   B 1 155 ? 26.735  36.376  38.571  1.00 27.39 ? 154 TYR   B CE2  1 
ATOM   7070  C  CZ   . TYR   B 1 155 ? 27.891  36.952  39.022  1.00 27.22 ? 154 TYR   B CZ   1 
ATOM   7071  O  OH   . TYR   B 1 155 ? 27.785  37.943  39.977  1.00 28.56 ? 154 TYR   B OH   1 
ATOM   7072  H  H    . TYR   B 1 155 ? 26.646  34.966  34.439  1.00 28.62 ? 154 TYR   B H    1 
ATOM   7073  H  HA   . TYR   B 1 155 ? 29.191  35.023  34.896  1.00 28.89 ? 154 TYR   B HA   1 
ATOM   7074  H  HB2  . TYR   B 1 155 ? 27.157  33.465  36.009  1.00 33.91 ? 154 TYR   B HB2  1 
ATOM   7075  H  HB3  . TYR   B 1 155 ? 28.665  33.148  36.399  1.00 33.91 ? 154 TYR   B HB3  1 
ATOM   7076  H  HD1  . TYR   B 1 155 ? 29.999  35.248  37.278  1.00 35.85 ? 154 TYR   B HD1  1 
ATOM   7077  H  HD2  . TYR   B 1 155 ? 26.002  34.975  37.349  1.00 34.02 ? 154 TYR   B HD2  1 
ATOM   7078  H  HE1  . TYR   B 1 155 ? 29.900  36.923  38.877  1.00 35.84 ? 154 TYR   B HE1  1 
ATOM   7079  H  HE2  . TYR   B 1 155 ? 25.913  36.667  38.893  1.00 32.86 ? 154 TYR   B HE2  1 
ATOM   7080  H  HH   . TYR   B 1 155 ? 28.322  37.795  40.606  1.00 34.27 ? 154 TYR   B HH   1 
ATOM   7081  N  N    . CYS   B 1 156 ? 28.275  32.416  33.273  1.00 28.99 ? 155 CYS   B N    1 
ATOM   7082  C  CA   . CYS   B 1 156 ? 28.782  31.270  32.531  1.00 29.70 ? 155 CYS   B CA   1 
ATOM   7083  C  C    . CYS   B 1 156 ? 29.202  31.609  31.121  1.00 30.71 ? 155 CYS   B C    1 
ATOM   7084  O  O    . CYS   B 1 156 ? 29.618  30.701  30.388  1.00 27.49 ? 155 CYS   B O    1 
ATOM   7085  C  CB   . CYS   B 1 156 ? 27.725  30.161  32.477  1.00 28.50 ? 155 CYS   B CB   1 
ATOM   7086  S  SG   . CYS   B 1 156 ? 27.375  29.519  34.083  1.00 27.59 ? 155 CYS   B SG   1 
ATOM   7087  H  H    . CYS   B 1 156 ? 27.422  32.518  33.244  1.00 34.79 ? 155 CYS   B H    1 
ATOM   7088  H  HA   . CYS   B 1 156 ? 29.558  30.931  33.003  1.00 35.64 ? 155 CYS   B HA   1 
ATOM   7089  H  HB2  . CYS   B 1 156 ? 26.903  30.520  32.106  1.00 34.20 ? 155 CYS   B HB2  1 
ATOM   7090  H  HB3  . CYS   B 1 156 ? 28.050  29.435  31.922  1.00 34.20 ? 155 CYS   B HB3  1 
ATOM   7091  H  HG   . CYS   B 1 156 ? 27.109  28.352  33.988  1.00 33.11 ? 155 CYS   B HG   1 
ATOM   7092  N  N    . ASN   B 1 157 ? 29.101  32.877  30.724  1.00 27.74 ? 156 ASN   B N    1 
ATOM   7093  C  CA   . ASN   B 1 157 ? 29.453  33.318  29.383  1.00 28.33 ? 156 ASN   B CA   1 
ATOM   7094  C  C    . ASN   B 1 157 ? 28.699  32.530  28.322  1.00 30.04 ? 156 ASN   B C    1 
ATOM   7095  O  O    . ASN   B 1 157 ? 29.258  32.090  27.319  1.00 29.56 ? 156 ASN   B O    1 
ATOM   7096  C  CB   . ASN   B 1 157 ? 30.954  33.207  29.178  1.00 34.72 ? 156 ASN   B CB   1 
ATOM   7097  C  CG   . ASN   B 1 157 ? 31.691  34.447  29.626  1.00 37.64 ? 156 ASN   B CG   1 
ATOM   7098  O  OD1  . ASN   B 1 157 ? 31.805  35.428  28.881  1.00 45.71 ? 156 ASN   B OD1  1 
ATOM   7099  N  ND2  . ASN   B 1 157 ? 32.103  34.451  30.892  1.00 42.85 ? 156 ASN   B ND2  1 
ATOM   7100  H  H    . ASN   B 1 157 ? 28.823  33.514  31.230  1.00 33.29 ? 156 ASN   B H    1 
ATOM   7101  H  HA   . ASN   B 1 157 ? 29.192  34.247  29.285  1.00 34.00 ? 156 ASN   B HA   1 
ATOM   7102  H  HB2  . ASN   B 1 157 ? 31.290  32.455  29.690  1.00 41.66 ? 156 ASN   B HB2  1 
ATOM   7103  H  HB3  . ASN   B 1 157 ? 31.136  33.073  28.234  1.00 41.66 ? 156 ASN   B HB3  1 
ATOM   7104  H  HD21 . ASN   B 1 157 ? 31.944  33.774  31.398  1.00 51.42 ? 156 ASN   B HD21 1 
ATOM   7105  H  HD22 . ASN   B 1 157 ? 32.528  35.130  31.203  1.00 51.42 ? 156 ASN   B HD22 1 
ATOM   7106  N  N    . LYS   B 1 158 ? 27.404  32.377  28.538  1.00 24.32 ? 157 LYS   B N    1 
ATOM   7107  C  CA   . LYS   B 1 158 ? 26.506  31.777  27.565  1.00 28.84 ? 157 LYS   B CA   1 
ATOM   7108  C  C    . LYS   B 1 158 ? 25.549  32.851  27.070  1.00 30.96 ? 157 LYS   B C    1 
ATOM   7109  O  O    . LYS   B 1 158 ? 25.201  33.770  27.814  1.00 33.12 ? 157 LYS   B O    1 
ATOM   7110  C  CB   . LYS   B 1 158 ? 25.707  30.621  28.167  1.00 26.05 ? 157 LYS   B CB   1 
ATOM   7111  C  CG   . LYS   B 1 158 ? 26.531  29.477  28.730  1.00 28.87 ? 157 LYS   B CG   1 
ATOM   7112  C  CD   . LYS   B 1 158 ? 27.255  28.681  27.634  1.00 31.43 ? 157 LYS   B CD   1 
ATOM   7113  C  CE   . LYS   B 1 158 ? 28.575  28.117  28.112  1.00 37.65 ? 157 LYS   B CE   1 
ATOM   7114  N  NZ   . LYS   B 1 158 ? 29.115  27.098  27.166  1.00 34.73 ? 157 LYS   B NZ   1 
ATOM   7115  H  H    . LYS   B 1 158 ? 27.009  32.619  29.263  1.00 29.18 ? 157 LYS   B H    1 
ATOM   7116  H  HA   . LYS   B 1 158 ? 27.018  31.422  26.821  1.00 34.61 ? 157 LYS   B HA   1 
ATOM   7117  H  HB2  . LYS   B 1 158 ? 25.166  30.970  28.892  1.00 31.27 ? 157 LYS   B HB2  1 
ATOM   7118  H  HB3  . LYS   B 1 158 ? 25.137  30.252  27.474  1.00 31.27 ? 157 LYS   B HB3  1 
ATOM   7119  H  HG2  . LYS   B 1 158 ? 27.200  29.835  29.334  1.00 34.65 ? 157 LYS   B HG2  1 
ATOM   7120  H  HG3  . LYS   B 1 158 ? 25.945  28.868  29.207  1.00 34.65 ? 157 LYS   B HG3  1 
ATOM   7121  H  HD2  . LYS   B 1 158 ? 26.694  27.940  27.356  1.00 37.71 ? 157 LYS   B HD2  1 
ATOM   7122  H  HD3  . LYS   B 1 158 ? 27.431  29.265  26.880  1.00 37.71 ? 157 LYS   B HD3  1 
ATOM   7123  H  HE2  . LYS   B 1 158 ? 29.223  28.836  28.187  1.00 45.18 ? 157 LYS   B HE2  1 
ATOM   7124  H  HE3  . LYS   B 1 158 ? 28.449  27.694  28.976  1.00 45.18 ? 157 LYS   B HE3  1 
ATOM   7125  H  HZ1  . LYS   B 1 158 ? 29.868  26.751  27.489  1.00 41.68 ? 157 LYS   B HZ1  1 
ATOM   7126  H  HZ2  . LYS   B 1 158 ? 28.521  26.445  27.051  1.00 41.68 ? 157 LYS   B HZ2  1 
ATOM   7127  H  HZ3  . LYS   B 1 158 ? 29.285  27.475  26.377  1.00 41.68 ? 157 LYS   B HZ3  1 
ATOM   7128  N  N    . THR   B 1 159 ? 25.197  32.792  25.803  1.00 27.08 ? 158 THR   B N    1 
ATOM   7129  C  CA   . THR   B 1 159 ? 24.162  33.670  25.285  1.00 32.00 ? 158 THR   B CA   1 
ATOM   7130  C  C    . THR   B 1 159 ? 22.824  32.956  25.208  1.00 30.58 ? 158 THR   B C    1 
ATOM   7131  O  O    . THR   B 1 159 ? 22.748  31.725  25.154  1.00 25.98 ? 158 THR   B O    1 
ATOM   7132  C  CB   . THR   B 1 159 ? 24.553  34.218  23.917  1.00 35.49 ? 158 THR   B CB   1 
ATOM   7133  O  OG1  . THR   B 1 159 ? 24.918  33.142  23.053  1.00 38.85 ? 158 THR   B OG1  1 
ATOM   7134  C  CG2  . THR   B 1 159 ? 25.736  35.172  24.067  1.00 41.25 ? 158 THR   B CG2  1 
ATOM   7135  H  H    . THR   B 1 159 ? 25.540  32.257  25.224  1.00 32.50 ? 158 THR   B H    1 
ATOM   7136  H  HA   . THR   B 1 159 ? 24.055  34.421  25.890  1.00 38.40 ? 158 THR   B HA   1 
ATOM   7137  H  HB   . THR   B 1 159 ? 23.807  34.698  23.526  1.00 42.59 ? 158 THR   B HB   1 
ATOM   7138  H  HG1  . THR   B 1 159 ? 24.350  33.061  22.440  1.00 46.62 ? 158 THR   B HG1  1 
ATOM   7139  H  HG21 . THR   B 1 159 ? 25.516  36.037  23.686  1.00 49.50 ? 158 THR   B HG21 1 
ATOM   7140  H  HG22 . THR   B 1 159 ? 25.952  35.288  25.006  1.00 49.50 ? 158 THR   B HG22 1 
ATOM   7141  H  HG23 . THR   B 1 159 ? 26.512  34.814  23.608  1.00 49.50 ? 158 THR   B HG23 1 
ATOM   7142  N  N    . VAL   B 1 160 ? 21.756  33.761  25.214  1.00 28.05 ? 159 VAL   B N    1 
ATOM   7143  C  CA   . VAL   B 1 160 ? 20.410  33.227  25.023  1.00 21.68 ? 159 VAL   B CA   1 
ATOM   7144  C  C    . VAL   B 1 160 ? 20.350  32.496  23.692  1.00 21.66 ? 159 VAL   B C    1 
ATOM   7145  O  O    . VAL   B 1 160 ? 20.798  33.017  22.660  1.00 27.08 ? 159 VAL   B O    1 
ATOM   7146  C  CB   . VAL   B 1 160 ? 19.383  34.365  25.089  1.00 27.40 ? 159 VAL   B CB   1 
ATOM   7147  C  CG1  . VAL   B 1 160 ? 17.996  33.884  24.657  1.00 25.18 ? 159 VAL   B CG1  1 
ATOM   7148  C  CG2  . VAL   B 1 160 ? 19.338  34.919  26.517  1.00 29.76 ? 159 VAL   B CG2  1 
ATOM   7149  H  H    . VAL   B 1 160 ? 21.786  34.613  25.326  1.00 33.65 ? 159 VAL   B H    1 
ATOM   7150  H  HA   . VAL   B 1 160 ? 20.208  32.594  25.729  1.00 26.02 ? 159 VAL   B HA   1 
ATOM   7151  H  HB   . VAL   B 1 160 ? 19.646  35.071  24.478  1.00 32.88 ? 159 VAL   B HB   1 
ATOM   7152  H  HG11 . VAL   B 1 160 ? 17.328  34.499  24.997  1.00 30.21 ? 159 VAL   B HG11 1 
ATOM   7153  H  HG12 . VAL   B 1 160 ? 17.959  33.857  23.688  1.00 30.21 ? 159 VAL   B HG12 1 
ATOM   7154  H  HG13 . VAL   B 1 160 ? 17.844  32.996  25.018  1.00 30.21 ? 159 VAL   B HG13 1 
ATOM   7155  H  HG21 . VAL   B 1 160 ? 19.360  35.888  26.481  1.00 35.72 ? 159 VAL   B HG21 1 
ATOM   7156  H  HG22 . VAL   B 1 160 ? 18.520  34.623  26.946  1.00 35.72 ? 159 VAL   B HG22 1 
ATOM   7157  H  HG23 . VAL   B 1 160 ? 20.107  34.590  27.008  1.00 35.72 ? 159 VAL   B HG23 1 
ATOM   7158  N  N    . GLY   B 1 161 ? 19.817  31.272  23.714  1.00 20.39 ? 160 GLY   B N    1 
ATOM   7159  C  CA   . GLY   B 1 161 ? 19.712  30.436  22.518  1.00 20.85 ? 160 GLY   B CA   1 
ATOM   7160  C  C    . GLY   B 1 161 ? 20.762  29.353  22.381  1.00 21.65 ? 160 GLY   B C    1 
ATOM   7161  O  O    . GLY   B 1 161 ? 20.603  28.448  21.527  1.00 24.69 ? 160 GLY   B O    1 
ATOM   7162  H  H    . GLY   B 1 161 ? 19.504  30.898  24.423  1.00 24.46 ? 160 GLY   B H    1 
ATOM   7163  H  HA2  . GLY   B 1 161 ? 18.844  30.004  22.521  1.00 25.02 ? 160 GLY   B HA2  1 
ATOM   7164  H  HA3  . GLY   B 1 161 ? 19.778  31.008  21.737  1.00 25.02 ? 160 GLY   B HA3  1 
ATOM   7165  N  N    . GLU   B 1 162 ? 21.830  29.434  23.160  1.00 21.57 ? 161 GLU   B N    1 
ATOM   7166  C  CA   . GLU   B 1 162 ? 22.921  28.475  23.164  1.00 23.80 ? 161 GLU   B CA   1 
ATOM   7167  C  C    . GLU   B 1 162 ? 22.595  27.396  24.182  1.00 25.01 ? 161 GLU   B C    1 
ATOM   7168  O  O    . GLU   B 1 162 ? 22.289  27.715  25.322  1.00 23.92 ? 161 GLU   B O    1 
ATOM   7169  C  CB   . GLU   B 1 162 ? 24.207  29.207  23.537  1.00 25.85 ? 161 GLU   B CB   1 
ATOM   7170  C  CG   . GLU   B 1 162 ? 25.502  28.458  23.433  1.00 33.97 ? 161 GLU   B CG   1 
ATOM   7171  C  CD   . GLU   B 1 162 ? 26.685  29.382  23.717  1.00 33.97 ? 161 GLU   B CD   1 
ATOM   7172  O  OE1  . GLU   B 1 162 ? 26.466  30.544  24.157  1.00 33.22 ? 161 GLU   B OE1  1 
ATOM   7173  O  OE2  . GLU   B 1 162 ? 27.839  28.947  23.515  1.00 36.26 ? 161 GLU   B OE2  1 
ATOM   7174  H  H    . GLU   B 1 162 ? 21.953  30.071  23.725  1.00 25.89 ? 161 GLU   B H    1 
ATOM   7175  H  HA   . GLU   B 1 162 ? 23.042  28.053  22.299  1.00 28.56 ? 161 GLU   B HA   1 
ATOM   7176  H  HB2  . GLU   B 1 162 ? 24.286  29.979  22.954  1.00 31.02 ? 161 GLU   B HB2  1 
ATOM   7177  H  HB3  . GLU   B 1 162 ? 24.126  29.495  24.459  1.00 31.02 ? 161 GLU   B HB3  1 
ATOM   7178  H  HG2  . GLU   B 1 162 ? 25.511  27.737  24.081  1.00 40.76 ? 161 GLU   B HG2  1 
ATOM   7179  H  HG3  . GLU   B 1 162 ? 25.598  28.101  22.537  1.00 40.76 ? 161 GLU   B HG3  1 
ATOM   7180  N  N    . LEU   B 1 163 ? 22.597  26.138  23.764  1.00 19.80 ? 162 LEU   B N    1 
ATOM   7181  C  CA   . LEU   B 1 163 ? 22.392  25.064  24.736  1.00 18.71 ? 162 LEU   B CA   1 
ATOM   7182  C  C    . LEU   B 1 163 ? 23.658  24.893  25.567  1.00 19.67 ? 162 LEU   B C    1 
ATOM   7183  O  O    . LEU   B 1 163 ? 24.767  24.768  25.025  1.00 21.38 ? 162 LEU   B O    1 
ATOM   7184  C  CB   . LEU   B 1 163 ? 22.043  23.759  24.043  1.00 23.54 ? 162 LEU   B CB   1 
ATOM   7185  C  CG   . LEU   B 1 163 ? 21.793  22.570  24.982  1.00 26.26 ? 162 LEU   B CG   1 
ATOM   7186  C  CD1  . LEU   B 1 163 ? 20.563  22.763  25.849  1.00 22.02 ? 162 LEU   B CD1  1 
ATOM   7187  C  CD2  . LEU   B 1 163 ? 21.706  21.262  24.168  1.00 23.89 ? 162 LEU   B CD2  1 
ATOM   7188  H  H    . LEU   B 1 163 ? 22.712  25.883  22.951  1.00 23.76 ? 162 LEU   B H    1 
ATOM   7189  H  HA   . LEU   B 1 163 ? 21.649  25.292  25.317  1.00 22.45 ? 162 LEU   B HA   1 
ATOM   7190  H  HB2  . LEU   B 1 163 ? 21.235  23.894  23.523  1.00 28.25 ? 162 LEU   B HB2  1 
ATOM   7191  H  HB3  . LEU   B 1 163 ? 22.778  23.518  23.457  1.00 28.25 ? 162 LEU   B HB3  1 
ATOM   7192  H  HG   . LEU   B 1 163 ? 22.543  22.503  25.594  1.00 31.51 ? 162 LEU   B HG   1 
ATOM   7193  H  HD11 . LEU   B 1 163 ? 20.187  21.895  26.063  1.00 26.42 ? 162 LEU   B HD11 1 
ATOM   7194  H  HD12 . LEU   B 1 163 ? 20.820  23.222  26.664  1.00 26.42 ? 162 LEU   B HD12 1 
ATOM   7195  H  HD13 . LEU   B 1 163 ? 19.913  23.294  25.362  1.00 26.42 ? 162 LEU   B HD13 1 
ATOM   7196  H  HD21 . LEU   B 1 163 ? 22.603  20.937  23.994  1.00 28.67 ? 162 LEU   B HD21 1 
ATOM   7197  H  HD22 . LEU   B 1 163 ? 21.209  20.604  24.679  1.00 28.67 ? 162 LEU   B HD22 1 
ATOM   7198  H  HD23 . LEU   B 1 163 ? 21.251  21.441  23.330  1.00 28.67 ? 162 LEU   B HD23 1 
ATOM   7199  N  N    . GLY   B 1 164 ? 23.513  24.897  26.896  1.00 20.22 ? 163 GLY   B N    1 
ATOM   7200  C  CA   . GLY   B 1 164 ? 24.623  24.647  27.781  1.00 22.54 ? 163 GLY   B CA   1 
ATOM   7201  C  C    . GLY   B 1 164 ? 24.502  23.283  28.442  1.00 18.29 ? 163 GLY   B C    1 
ATOM   7202  O  O    . GLY   B 1 164 ? 23.493  22.602  28.315  1.00 18.02 ? 163 GLY   B O    1 
ATOM   7203  H  H    . GLY   B 1 164 ? 22.768  25.044  27.301  1.00 24.26 ? 163 GLY   B H    1 
ATOM   7204  H  HA2  . GLY   B 1 164 ? 25.453  24.676  27.280  1.00 27.05 ? 163 GLY   B HA2  1 
ATOM   7205  H  HA3  . GLY   B 1 164 ? 24.648  25.326  28.473  1.00 27.05 ? 163 GLY   B HA3  1 
ATOM   7206  N  N    . ASP   B 1 165 ? 25.577  22.910  29.145  1.00 17.27 ? 164 ASP   B N    1 
ATOM   7207  C  CA   . ASP   B 1 165 ? 25.728  21.642  29.854  1.00 14.82 ? 164 ASP   B CA   1 
ATOM   7208  C  C    . ASP   B 1 165 ? 25.441  21.909  31.334  1.00 19.72 ? 164 ASP   B C    1 
ATOM   7209  O  O    . ASP   B 1 165 ? 26.030  22.825  31.925  1.00 18.57 ? 164 ASP   B O    1 
ATOM   7210  C  CB   . ASP   B 1 165 ? 27.149  21.110  29.640  1.00 18.52 ? 164 ASP   B CB   1 
ATOM   7211  C  CG   . ASP   B 1 165 ? 27.488  19.869  30.460  1.00 18.94 ? 164 ASP   B CG   1 
ATOM   7212  O  OD1  . ASP   B 1 165 ? 27.453  19.925  31.729  1.00 21.33 ? 164 ASP   B OD1  1 
ATOM   7213  O  OD2  . ASP   B 1 165 ? 27.856  18.845  29.841  1.00 21.57 ? 164 ASP   B OD2  1 
ATOM   7214  H  H    . ASP   B 1 165 ? 26.273  23.408  29.228  1.00 20.73 ? 164 ASP   B H    1 
ATOM   7215  H  HA   . ASP   B 1 165 ? 25.108  20.965  29.540  1.00 17.79 ? 164 ASP   B HA   1 
ATOM   7216  H  HB2  . ASP   B 1 165 ? 27.256  20.881  28.704  1.00 22.22 ? 164 ASP   B HB2  1 
ATOM   7217  H  HB3  . ASP   B 1 165 ? 27.779  21.805  29.886  1.00 22.22 ? 164 ASP   B HB3  1 
ATOM   7218  N  N    . VAL   B 1 166 ? 24.536  21.115  31.920  1.00 17.84 ? 165 VAL   B N    1 
ATOM   7219  C  CA   . VAL   B 1 166 ? 24.114  21.382  33.309  1.00 15.93 ? 165 VAL   B CA   1 
ATOM   7220  C  C    . VAL   B 1 166 ? 25.300  21.254  34.267  1.00 18.29 ? 165 VAL   B C    1 
ATOM   7221  O  O    . VAL   B 1 166 ? 25.510  22.107  35.149  1.00 17.89 ? 165 VAL   B O    1 
ATOM   7222  C  CB   . VAL   B 1 166 ? 22.966  20.442  33.702  1.00 15.15 ? 165 VAL   B CB   1 
ATOM   7223  C  CG1  . VAL   B 1 166 ? 22.737  20.436  35.249  1.00 18.59 ? 165 VAL   B CG1  1 
ATOM   7224  C  CG2  . VAL   B 1 166 ? 21.657  20.847  33.046  1.00 16.16 ? 165 VAL   B CG2  1 
ATOM   7225  H  H    . VAL   B 1 166 ? 24.161  20.434  31.551  1.00 21.41 ? 165 VAL   B H    1 
ATOM   7226  H  HA   . VAL   B 1 166 ? 23.790  22.295  33.363  1.00 19.12 ? 165 VAL   B HA   1 
ATOM   7227  H  HB   . VAL   B 1 166 ? 23.223  19.557  33.401  1.00 18.18 ? 165 VAL   B HB   1 
ATOM   7228  H  HG11 . VAL   B 1 166 ? 21.837  20.123  35.434  1.00 22.31 ? 165 VAL   B HG11 1 
ATOM   7229  H  HG12 . VAL   B 1 166 ? 23.384  19.843  35.662  1.00 22.31 ? 165 VAL   B HG12 1 
ATOM   7230  H  HG13 . VAL   B 1 166 ? 22.850  21.337  35.589  1.00 22.31 ? 165 VAL   B HG13 1 
ATOM   7231  H  HG21 . VAL   B 1 166 ? 21.064  20.080  33.025  1.00 19.39 ? 165 VAL   B HG21 1 
ATOM   7232  H  HG22 . VAL   B 1 166 ? 21.254  21.563  33.560  1.00 19.39 ? 165 VAL   B HG22 1 
ATOM   7233  H  HG23 . VAL   B 1 166 ? 21.838  21.150  32.142  1.00 19.39 ? 165 VAL   B HG23 1 
ATOM   7234  N  N    . ARG   B 1 167 ? 26.047  20.155  34.160  1.00 18.79 ? 166 ARG   B N    1 
ATOM   7235  C  CA   . ARG   B 1 167 ? 27.230  19.953  34.999  1.00 21.10 ? 166 ARG   B CA   1 
ATOM   7236  C  C    . ARG   B 1 167 ? 28.208  21.124  34.896  1.00 24.94 ? 166 ARG   B C    1 
ATOM   7237  O  O    . ARG   B 1 167 ? 28.713  21.611  35.914  1.00 20.18 ? 166 ARG   B O    1 
ATOM   7238  C  CB   . ARG   B 1 167 ? 27.906  18.633  34.614  1.00 18.99 ? 166 ARG   B CB   1 
ATOM   7239  C  CG   . ARG   B 1 167 ? 29.234  18.319  35.345  1.00 20.82 ? 166 ARG   B CG   1 
ATOM   7240  C  CD   . ARG   B 1 167 ? 29.804  17.001  34.884  1.00 20.69 ? 166 ARG   B CD   1 
ATOM   7241  N  NE   . ARG   B 1 167 ? 30.484  17.176  33.594  1.00 23.36 ? 166 ARG   B NE   1 
ATOM   7242  C  CZ   . ARG   B 1 167 ? 31.701  17.671  33.425  1.00 35.21 ? 166 ARG   B CZ   1 
ATOM   7243  N  NH1  . ARG   B 1 167 ? 32.488  17.946  34.454  1.00 36.26 ? 166 ARG   B NH1  1 
ATOM   7244  N  NH2  . ARG   B 1 167 ? 32.149  17.877  32.187  1.00 33.40 ? 166 ARG   B NH2  1 
ATOM   7245  H  H    . ARG   B 1 167 ? 25.892  19.510  33.612  1.00 22.55 ? 166 ARG   B H    1 
ATOM   7246  H  HA   . ARG   B 1 167 ? 26.955  19.896  35.927  1.00 25.32 ? 166 ARG   B HA   1 
ATOM   7247  H  HB2  . ARG   B 1 167 ? 27.291  17.909  34.810  1.00 22.79 ? 166 ARG   B HB2  1 
ATOM   7248  H  HB3  . ARG   B 1 167 ? 28.099  18.656  33.664  1.00 22.79 ? 166 ARG   B HB3  1 
ATOM   7249  H  HG2  . ARG   B 1 167 ? 29.880  19.017  35.155  1.00 24.99 ? 166 ARG   B HG2  1 
ATOM   7250  H  HG3  . ARG   B 1 167 ? 29.072  18.267  36.300  1.00 24.99 ? 166 ARG   B HG3  1 
ATOM   7251  H  HD2  . ARG   B 1 167 ? 30.447  16.677  35.535  1.00 24.83 ? 166 ARG   B HD2  1 
ATOM   7252  H  HD3  . ARG   B 1 167 ? 29.088  16.355  34.775  1.00 24.83 ? 166 ARG   B HD3  1 
ATOM   7253  H  HE   . ARG   B 1 167 ? 30.056  16.936  32.888  1.00 28.03 ? 166 ARG   B HE   1 
ATOM   7254  H  HH11 . ARG   B 1 167 ? 32.213  17.803  35.257  1.00 43.52 ? 166 ARG   B HH11 1 
ATOM   7255  H  HH12 . ARG   B 1 167 ? 33.275  18.267  34.321  1.00 43.52 ? 166 ARG   B HH12 1 
ATOM   7256  H  HH21 . ARG   B 1 167 ? 31.650  17.689  31.512  1.00 40.08 ? 166 ARG   B HH21 1 
ATOM   7257  H  HH22 . ARG   B 1 167 ? 32.937  18.199  32.063  1.00 40.08 ? 166 ARG   B HH22 1 
ATOM   7258  N  N    . GLU   B 1 168 ? 28.473  21.613  33.678  1.00 19.74 ? 167 GLU   B N    1 
ATOM   7259  C  CA   . GLU   B 1 168 ? 29.376  22.752  33.524  1.00 20.15 ? 167 GLU   B CA   1 
ATOM   7260  C  C    . GLU   B 1 168 ? 28.803  24.003  34.176  1.00 21.27 ? 167 GLU   B C    1 
ATOM   7261  O  O    . GLU   B 1 168 ? 29.537  24.784  34.790  1.00 21.54 ? 167 GLU   B O    1 
ATOM   7262  C  CB   . GLU   B 1 168 ? 29.649  23.011  32.037  1.00 23.24 ? 167 GLU   B CB   1 
ATOM   7263  C  CG   . GLU   B 1 168 ? 30.341  21.851  31.343  1.00 23.32 ? 167 GLU   B CG   1 
ATOM   7264  C  CD   . GLU   B 1 168 ? 30.686  22.165  29.905  1.00 22.98 ? 167 GLU   B CD   1 
ATOM   7265  O  OE1  . GLU   B 1 168 ? 30.315  23.253  29.444  1.00 23.45 ? 167 GLU   B OE1  1 
ATOM   7266  O  OE2  . GLU   B 1 168 ? 31.341  21.324  29.279  1.00 32.27 ? 167 GLU   B OE2  1 
ATOM   7267  H  H    . GLU   B 1 168 ? 28.148  21.308  32.942  1.00 23.69 ? 167 GLU   B H    1 
ATOM   7268  H  HA   . GLU   B 1 168 ? 30.217  22.540  33.957  1.00 24.18 ? 167 GLU   B HA   1 
ATOM   7269  H  HB2  . GLU   B 1 168 ? 28.805  23.168  31.585  1.00 27.88 ? 167 GLU   B HB2  1 
ATOM   7270  H  HB3  . GLU   B 1 168 ? 30.220  23.791  31.954  1.00 27.88 ? 167 GLU   B HB3  1 
ATOM   7271  H  HG2  . GLU   B 1 168 ? 31.165  21.645  31.812  1.00 27.98 ? 167 GLU   B HG2  1 
ATOM   7272  H  HG3  . GLU   B 1 168 ? 29.753  21.079  31.351  1.00 27.98 ? 167 GLU   B HG3  1 
ATOM   7273  N  N    . THR   B 1 169 ? 27.488  24.204  34.045  1.00 18.42 ? 168 THR   B N    1 
ATOM   7274  C  CA   . THR   B 1 169 ? 26.821  25.366  34.605  1.00 18.51 ? 168 THR   B CA   1 
ATOM   7275  C  C    . THR   B 1 169 ? 26.894  25.328  36.118  1.00 21.42 ? 168 THR   B C    1 
ATOM   7276  O  O    . THR   B 1 169 ? 27.274  26.311  36.776  1.00 22.46 ? 168 THR   B O    1 
ATOM   7277  C  CB   . THR   B 1 169 ? 25.357  25.375  34.144  1.00 17.91 ? 168 THR   B CB   1 
ATOM   7278  O  OG1  . THR   B 1 169 ? 25.302  25.349  32.700  1.00 21.73 ? 168 THR   B OG1  1 
ATOM   7279  C  CG2  . THR   B 1 169 ? 24.615  26.595  34.641  1.00 24.57 ? 168 THR   B CG2  1 
ATOM   7280  H  H    . THR   B 1 169 ? 26.957  23.671  33.629  1.00 22.10 ? 168 THR   B H    1 
ATOM   7281  H  HA   . THR   B 1 169 ? 27.251  26.177  34.292  1.00 22.21 ? 168 THR   B HA   1 
ATOM   7282  H  HB   . THR   B 1 169 ? 24.917  24.592  34.511  1.00 21.50 ? 168 THR   B HB   1 
ATOM   7283  H  HG1  . THR   B 1 169 ? 25.001  24.611  32.437  1.00 26.08 ? 168 THR   B HG1  1 
ATOM   7284  H  HG21 . THR   B 1 169 ? 23.930  26.850  34.003  1.00 29.48 ? 168 THR   B HG21 1 
ATOM   7285  H  HG22 . THR   B 1 169 ? 24.195  26.403  35.494  1.00 29.48 ? 168 THR   B HG22 1 
ATOM   7286  H  HG23 . THR   B 1 169 ? 25.231  27.336  34.754  1.00 29.48 ? 168 THR   B HG23 1 
ATOM   7287  N  N    . MET   B 1 170 ? 26.557  24.181  36.679  1.00 18.62 ? 169 MET   B N    1 
ATOM   7288  C  CA   . MET   B 1 170 ? 26.577  24.053  38.126  1.00 19.60 ? 169 MET   B CA   1 
ATOM   7289  C  C    . MET   B 1 170 ? 28.010  24.242  38.631  1.00 20.21 ? 169 MET   B C    1 
ATOM   7290  O  O    . MET   B 1 170 ? 28.255  24.882  39.669  1.00 25.42 ? 169 MET   B O    1 
ATOM   7291  C  CB   . MET   B 1 170 ? 26.072  22.672  38.532  1.00 21.79 ? 169 MET   B CB   1 
ATOM   7292  C  CG   . MET   B 1 170 ? 24.553  22.357  38.312  1.00 24.96 ? 169 MET   B CG   1 
ATOM   7293  S  SD   . MET   B 1 170 ? 23.358  23.505  39.016  1.00 26.36 ? 169 MET   B SD   1 
ATOM   7294  C  CE   . MET   B 1 170 ? 23.307  22.985  40.732  1.00 25.73 ? 169 MET   B CE   1 
ATOM   7295  H  H    . MET   B 1 170 ? 26.316  23.473  36.254  1.00 22.34 ? 169 MET   B H    1 
ATOM   7296  H  HA   . MET   B 1 170 ? 25.987  24.715  38.519  1.00 23.51 ? 169 MET   B HA   1 
ATOM   7297  H  HB2  . MET   B 1 170 ? 26.570  22.013  38.023  1.00 26.15 ? 169 MET   B HB2  1 
ATOM   7298  H  HB3  . MET   B 1 170 ? 26.245  22.559  39.479  1.00 26.15 ? 169 MET   B HB3  1 
ATOM   7299  H  HG2  . MET   B 1 170 ? 24.389  22.333  37.356  1.00 29.95 ? 169 MET   B HG2  1 
ATOM   7300  H  HG3  . MET   B 1 170 ? 24.370  21.487  38.701  1.00 29.95 ? 169 MET   B HG3  1 
ATOM   7301  H  HE1  . MET   B 1 170 ? 22.382  22.868  40.999  1.00 30.88 ? 169 MET   B HE1  1 
ATOM   7302  H  HE2  . MET   B 1 170 ? 23.787  22.147  40.823  1.00 30.88 ? 169 MET   B HE2  1 
ATOM   7303  H  HE3  . MET   B 1 170 ? 23.725  23.667  41.281  1.00 30.88 ? 169 MET   B HE3  1 
ATOM   7304  N  N    . SER   B 1 171 ? 28.974  23.646  37.921  1.00 22.61 ? 170 SER   B N    1 
ATOM   7305  C  CA   . SER   B 1 171 ? 30.373  23.745  38.319  1.00 22.67 ? 170 SER   B CA   1 
ATOM   7306  C  C    . SER   B 1 171 ? 30.800  25.203  38.409  1.00 28.28 ? 170 SER   B C    1 
ATOM   7307  O  O    . SER   B 1 171 ? 31.442  25.615  39.377  1.00 28.63 ? 170 SER   B O    1 
ATOM   7308  C  CB   . SER   B 1 171 ? 31.269  22.992  37.343  1.00 28.53 ? 170 SER   B CB   1 
ATOM   7309  O  OG   . SER   B 1 171 ? 32.610  23.068  37.794  1.00 31.82 ? 170 SER   B OG   1 
ATOM   7310  H  H    . SER   B 1 171 ? 28.842  23.182  37.209  1.00 27.14 ? 170 SER   B H    1 
ATOM   7311  H  HA   . SER   B 1 171 ? 30.474  23.332  39.191  1.00 27.21 ? 170 SER   B HA   1 
ATOM   7312  H  HB2  . SER   B 1 171 ? 30.994  22.063  37.303  1.00 34.24 ? 170 SER   B HB2  1 
ATOM   7313  H  HB3  . SER   B 1 171 ? 31.201  23.397  36.464  1.00 34.24 ? 170 SER   B HB3  1 
ATOM   7314  H  HG   . SER   B 1 171 ? 32.974  23.764  37.496  1.00 38.19 ? 170 SER   B HG   1 
ATOM   7315  N  N    . TYR   B 1 172 ? 30.438  26.011  37.415  1.00 24.65 ? 171 TYR   B N    1 
ATOM   7316  C  CA   . TYR   B 1 172 ? 30.843  27.405  37.500  1.00 27.24 ? 171 TYR   B CA   1 
ATOM   7317  C  C    . TYR   B 1 172 ? 30.095  28.146  38.602  1.00 27.76 ? 171 TYR   B C    1 
ATOM   7318  O  O    . TYR   B 1 172 ? 30.686  28.957  39.323  1.00 29.92 ? 171 TYR   B O    1 
ATOM   7319  C  CB   . TYR   B 1 172 ? 30.633  28.132  36.189  1.00 31.69 ? 171 TYR   B CB   1 
ATOM   7320  C  CG   . TYR   B 1 172 ? 31.423  29.416  36.201  1.00 39.55 ? 171 TYR   B CG   1 
ATOM   7321  C  CD1  . TYR   B 1 172 ? 32.813  29.396  36.254  1.00 50.30 ? 171 TYR   B CD1  1 
ATOM   7322  C  CD2  . TYR   B 1 172 ? 30.786  30.644  36.257  1.00 44.82 ? 171 TYR   B CD2  1 
ATOM   7323  C  CE1  . TYR   B 1 172 ? 33.545  30.573  36.281  1.00 56.71 ? 171 TYR   B CE1  1 
ATOM   7324  C  CE2  . TYR   B 1 172 ? 31.508  31.829  36.294  1.00 46.36 ? 171 TYR   B CE2  1 
ATOM   7325  C  CZ   . TYR   B 1 172 ? 32.881  31.786  36.303  1.00 47.56 ? 171 TYR   B CZ   1 
ATOM   7326  O  OH   . TYR   B 1 172 ? 33.588  32.964  36.337  1.00 52.95 ? 171 TYR   B OH   1 
ATOM   7327  H  H    . TYR   B 1 172 ? 29.983  25.787  36.720  1.00 29.58 ? 171 TYR   B H    1 
ATOM   7328  H  HA   . TYR   B 1 172 ? 31.793  27.407  37.697  1.00 32.69 ? 171 TYR   B HA   1 
ATOM   7329  H  HB2  . TYR   B 1 172 ? 30.940  27.579  35.454  1.00 38.03 ? 171 TYR   B HB2  1 
ATOM   7330  H  HB3  . TYR   B 1 172 ? 29.693  28.342  36.077  1.00 38.03 ? 171 TYR   B HB3  1 
ATOM   7331  H  HD1  . TYR   B 1 172 ? 33.258  28.580  36.271  1.00 60.35 ? 171 TYR   B HD1  1 
ATOM   7332  H  HD2  . TYR   B 1 172 ? 29.856  30.675  36.269  1.00 53.78 ? 171 TYR   B HD2  1 
ATOM   7333  H  HE1  . TYR   B 1 172 ? 34.475  30.547  36.284  1.00 68.06 ? 171 TYR   B HE1  1 
ATOM   7334  H  HE2  . TYR   B 1 172 ? 31.065  32.646  36.313  1.00 55.64 ? 171 TYR   B HE2  1 
ATOM   7335  H  HH   . TYR   B 1 172 ? 33.903  33.087  37.106  1.00 63.54 ? 171 TYR   B HH   1 
ATOM   7336  N  N    . LEU   B 1 173 ? 28.798  27.893  38.751  1.00 20.51 ? 172 LEU   B N    1 
ATOM   7337  C  CA   . LEU   B 1 173 ? 28.063  28.535  39.838  1.00 21.81 ? 172 LEU   B CA   1 
ATOM   7338  C  C    . LEU   B 1 173 ? 28.648  28.156  41.190  1.00 24.92 ? 172 LEU   B C    1 
ATOM   7339  O  O    . LEU   B 1 173 ? 28.668  28.973  42.123  1.00 25.65 ? 172 LEU   B O    1 
ATOM   7340  C  CB   . LEU   B 1 173 ? 26.586  28.127  39.796  1.00 23.44 ? 172 LEU   B CB   1 
ATOM   7341  C  CG   . LEU   B 1 173 ? 25.816  28.706  38.593  1.00 23.78 ? 172 LEU   B CG   1 
ATOM   7342  C  CD1  . LEU   B 1 173 ? 24.361  28.296  38.618  1.00 21.75 ? 172 LEU   B CD1  1 
ATOM   7343  C  CD2  . LEU   B 1 173 ? 25.982  30.247  38.530  1.00 26.80 ? 172 LEU   B CD2  1 
ATOM   7344  H  H    . LEU   B 1 173 ? 28.332  27.369  38.252  1.00 24.61 ? 172 LEU   B H    1 
ATOM   7345  H  HA   . LEU   B 1 173 ? 28.125  29.496  39.720  1.00 26.17 ? 172 LEU   B HA   1 
ATOM   7346  H  HB2  . LEU   B 1 173 ? 26.532  27.160  39.745  1.00 28.13 ? 172 LEU   B HB2  1 
ATOM   7347  H  HB3  . LEU   B 1 173 ? 26.154  28.442  40.605  1.00 28.13 ? 172 LEU   B HB3  1 
ATOM   7348  H  HG   . LEU   B 1 173 ? 26.190  28.340  37.777  1.00 28.54 ? 172 LEU   B HG   1 
ATOM   7349  H  HD11 . LEU   B 1 173 ? 23.913  28.675  37.846  1.00 26.10 ? 172 LEU   B HD11 1 
ATOM   7350  H  HD12 . LEU   B 1 173 ? 24.305  27.328  38.591  1.00 26.10 ? 172 LEU   B HD12 1 
ATOM   7351  H  HD13 . LEU   B 1 173 ? 23.953  28.628  39.433  1.00 26.10 ? 172 LEU   B HD13 1 
ATOM   7352  H  HD21 . LEU   B 1 173 ? 25.242  30.625  38.029  1.00 32.16 ? 172 LEU   B HD21 1 
ATOM   7353  H  HD22 . LEU   B 1 173 ? 25.987  30.602  39.432  1.00 32.16 ? 172 LEU   B HD22 1 
ATOM   7354  H  HD23 . LEU   B 1 173 ? 26.820  30.457  38.088  1.00 32.16 ? 172 LEU   B HD23 1 
ATOM   7355  N  N    . PHE   B 1 174 ? 29.081  26.902  41.333  1.00 22.56 ? 173 PHE   B N    1 
ATOM   7356  C  CA   . PHE   B 1 174 ? 29.680  26.465  42.591  1.00 23.92 ? 173 PHE   B CA   1 
ATOM   7357  C  C    . PHE   B 1 174 ? 30.957  27.247  42.902  1.00 25.55 ? 173 PHE   B C    1 
ATOM   7358  O  O    . PHE   B 1 174 ? 31.309  27.434  44.084  1.00 27.02 ? 173 PHE   B O    1 
ATOM   7359  C  CB   . PHE   B 1 174 ? 29.990  24.954  42.552  1.00 25.00 ? 173 PHE   B CB   1 
ATOM   7360  C  CG   . PHE   B 1 174 ? 28.768  24.047  42.542  1.00 19.68 ? 173 PHE   B CG   1 
ATOM   7361  C  CD1  . PHE   B 1 174 ? 27.506  24.515  42.856  1.00 20.74 ? 173 PHE   B CD1  1 
ATOM   7362  C  CD2  . PHE   B 1 174 ? 28.912  22.695  42.202  1.00 23.79 ? 173 PHE   B CD2  1 
ATOM   7363  C  CE1  . PHE   B 1 174 ? 26.408  23.654  42.832  1.00 22.96 ? 173 PHE   B CE1  1 
ATOM   7364  C  CE2  . PHE   B 1 174 ? 27.816  21.837  42.180  1.00 19.16 ? 173 PHE   B CE2  1 
ATOM   7365  C  CZ   . PHE   B 1 174 ? 26.572  22.315  42.508  1.00 22.91 ? 173 PHE   B CZ   1 
ATOM   7366  H  H    . PHE   B 1 174 ? 29.040  26.295  40.725  1.00 27.08 ? 173 PHE   B H    1 
ATOM   7367  H  HA   . PHE   B 1 174 ? 29.039  26.620  43.303  1.00 28.70 ? 173 PHE   B HA   1 
ATOM   7368  H  HB2  . PHE   B 1 174 ? 30.498  24.766  41.747  1.00 30.01 ? 173 PHE   B HB2  1 
ATOM   7369  H  HB3  . PHE   B 1 174 ? 30.515  24.728  43.336  1.00 30.01 ? 173 PHE   B HB3  1 
ATOM   7370  H  HD1  . PHE   B 1 174 ? 27.387  25.408  43.086  1.00 24.89 ? 173 PHE   B HD1  1 
ATOM   7371  H  HD2  . PHE   B 1 174 ? 29.755  22.366  41.986  1.00 28.54 ? 173 PHE   B HD2  1 
ATOM   7372  H  HE1  . PHE   B 1 174 ? 25.561  23.980  43.033  1.00 27.55 ? 173 PHE   B HE1  1 
ATOM   7373  H  HE2  . PHE   B 1 174 ? 27.925  20.944  41.943  1.00 22.99 ? 173 PHE   B HE2  1 
ATOM   7374  H  HZ   . PHE   B 1 174 ? 25.840  21.742  42.514  1.00 27.50 ? 173 PHE   B HZ   1 
ATOM   7375  N  N    . GLN   B 1 175 ? 31.648  27.724  41.868  1.00 25.99 ? 174 GLN   B N    1 
ATOM   7376  C  CA   . GLN   B 1 175 ? 32.848  28.520  42.084  1.00 26.79 ? 174 GLN   B CA   1 
ATOM   7377  C  C    . GLN   B 1 175 ? 32.521  29.856  42.717  1.00 33.60 ? 174 GLN   B C    1 
ATOM   7378  O  O    . GLN   B 1 175 ? 33.426  30.513  43.228  1.00 33.47 ? 174 GLN   B O    1 
ATOM   7379  C  CB   . GLN   B 1 175 ? 33.596  28.848  40.799  1.00 33.43 ? 174 GLN   B CB   1 
ATOM   7380  C  CG   . GLN   B 1 175 ? 33.709  27.812  39.735  1.00 42.79 ? 174 GLN   B CG   1 
ATOM   7381  C  CD   . GLN   B 1 175 ? 34.816  26.819  39.932  1.00 52.65 ? 174 GLN   B CD   1 
ATOM   7382  O  OE1  . GLN   B 1 175 ? 35.462  26.773  40.981  1.00 51.24 ? 174 GLN   B OE1  1 
ATOM   7383  N  NE2  . GLN   B 1 175 ? 35.086  26.040  38.879  1.00 53.24 ? 174 GLN   B NE2  1 
ATOM   7384  H  H    . GLN   B 1 175 ? 31.444  27.601  41.041  1.00 31.19 ? 174 GLN   B H    1 
ATOM   7385  H  HA   . GLN   B 1 175 ? 33.424  27.976  42.643  1.00 32.15 ? 174 GLN   B HA   1 
ATOM   7386  H  HB2  . GLN   B 1 175 ? 33.152  29.608  40.392  1.00 40.12 ? 174 GLN   B HB2  1 
ATOM   7387  H  HB3  . GLN   B 1 175 ? 34.504  29.085  41.045  1.00 40.12 ? 174 GLN   B HB3  1 
ATOM   7388  H  HG2  . GLN   B 1 175 ? 32.876  27.316  39.700  1.00 51.35 ? 174 GLN   B HG2  1 
ATOM   7389  H  HG3  . GLN   B 1 175 ? 33.866  28.258  38.888  1.00 51.35 ? 174 GLN   B HG3  1 
ATOM   7390  H  HE21 . GLN   B 1 175 ? 34.636  26.129  38.152  1.00 63.89 ? 174 GLN   B HE21 1 
ATOM   7391  H  HE22 . GLN   B 1 175 ? 35.710  25.450  38.929  1.00 63.89 ? 174 GLN   B HE22 1 
ATOM   7392  N  N    . HIS   B 1 176 ? 31.265  30.297  42.630  1.00 27.34 ? 175 HIS   B N    1 
ATOM   7393  C  CA   . HIS   B 1 176 ? 30.808  31.531  43.246  1.00 30.06 ? 175 HIS   B CA   1 
ATOM   7394  C  C    . HIS   B 1 176 ? 30.010  31.262  44.502  1.00 30.08 ? 175 HIS   B C    1 
ATOM   7395  O  O    . HIS   B 1 176 ? 29.231  32.119  44.929  1.00 32.40 ? 175 HIS   B O    1 
ATOM   7396  C  CB   . HIS   B 1 176 ? 29.947  32.338  42.275  1.00 29.32 ? 175 HIS   B CB   1 
ATOM   7397  C  CG   . HIS   B 1 176 ? 30.719  33.048  41.217  1.00 28.92 ? 175 HIS   B CG   1 
ATOM   7398  N  ND1  . HIS   B 1 176 ? 31.370  34.241  41.450  1.00 36.29 ? 175 HIS   B ND1  1 
ATOM   7399  C  CD2  . HIS   B 1 176 ? 30.940  32.743  39.917  1.00 38.22 ? 175 HIS   B CD2  1 
ATOM   7400  C  CE1  . HIS   B 1 176 ? 31.952  34.642  40.333  1.00 40.69 ? 175 HIS   B CE1  1 
ATOM   7401  N  NE2  . HIS   B 1 176 ? 31.708  33.752  39.390  1.00 36.93 ? 175 HIS   B NE2  1 
ATOM   7402  H  H    . HIS   B 1 176 ? 30.644  29.882  42.204  1.00 32.81 ? 175 HIS   B H    1 
ATOM   7403  H  HA   . HIS   B 1 176 ? 31.588  32.062  43.468  1.00 36.08 ? 175 HIS   B HA   1 
ATOM   7404  H  HB2  . HIS   B 1 176 ? 29.330  31.734  41.833  1.00 35.19 ? 175 HIS   B HB2  1 
ATOM   7405  H  HB3  . HIS   B 1 176 ? 29.455  33.006  42.778  1.00 35.19 ? 175 HIS   B HB3  1 
ATOM   7406  H  HD2  . HIS   B 1 176 ? 30.630  31.992  39.466  1.00 45.86 ? 175 HIS   B HD2  1 
ATOM   7407  H  HE1  . HIS   B 1 176 ? 32.450  35.421  40.230  1.00 48.83 ? 175 HIS   B HE1  1 
ATOM   7408  H  HE2  . HIS   B 1 176 ? 31.985  33.796  38.577  1.00 44.32 ? 175 HIS   B HE2  1 
ATOM   7409  N  N    . ALA   B 1 177 ? 30.117  30.057  45.054  1.00 25.76 ? 176 ALA   B N    1 
ATOM   7410  C  CA   . ALA   B 1 177 ? 29.396  29.683  46.252  1.00 24.83 ? 176 ALA   B CA   1 
ATOM   7411  C  C    . ALA   B 1 177 ? 30.399  29.428  47.372  1.00 27.61 ? 176 ALA   B C    1 
ATOM   7412  O  O    . ALA   B 1 177 ? 31.586  29.167  47.136  1.00 29.64 ? 176 ALA   B O    1 
ATOM   7413  C  CB   . ALA   B 1 177 ? 28.525  28.441  46.051  1.00 25.57 ? 176 ALA   B CB   1 
ATOM   7414  H  H    . ALA   B 1 177 ? 30.613  29.428  44.741  1.00 30.91 ? 176 ALA   B H    1 
ATOM   7415  H  HA   . ALA   B 1 177 ? 28.800  30.407  46.500  1.00 29.80 ? 176 ALA   B HA   1 
ATOM   7416  H  HB1  . ALA   B 1 177 ? 27.643  28.611  46.418  1.00 30.68 ? 176 ALA   B HB1  1 
ATOM   7417  H  HB2  . ALA   B 1 177 ? 28.457  28.254  45.102  1.00 30.68 ? 176 ALA   B HB2  1 
ATOM   7418  H  HB3  . ALA   B 1 177 ? 28.935  27.691  46.508  1.00 30.68 ? 176 ALA   B HB3  1 
ATOM   7419  N  N    . ASN   B 1 178 ? 29.908  29.493  48.597  1.00 26.04 ? 177 ASN   B N    1 
ATOM   7420  C  CA   . ASN   B 1 178 ? 30.768  29.256  49.751  1.00 30.71 ? 177 ASN   B CA   1 
ATOM   7421  C  C    . ASN   B 1 178 ? 30.792  27.759  50.023  1.00 27.84 ? 177 ASN   B C    1 
ATOM   7422  O  O    . ASN   B 1 178 ? 30.016  27.244  50.818  1.00 30.45 ? 177 ASN   B O    1 
ATOM   7423  C  CB   . ASN   B 1 178 ? 30.283  30.008  50.979  1.00 34.91 ? 177 ASN   B CB   1 
ATOM   7424  C  CG   . ASN   B 1 178 ? 31.274  29.901  52.131  1.00 46.03 ? 177 ASN   B CG   1 
ATOM   7425  O  OD1  . ASN   B 1 178 ? 32.272  29.174  52.038  1.00 38.02 ? 177 ASN   B OD1  1 
ATOM   7426  N  ND2  . ASN   B 1 178 ? 30.987  30.590  53.231  1.00 55.60 ? 177 ASN   B ND2  1 
ATOM   7427  H  H    . ASN   B 1 178 ? 29.088  29.671  48.788  1.00 31.25 ? 177 ASN   B H    1 
ATOM   7428  H  HA   . ASN   B 1 178 ? 31.660  29.565  49.531  1.00 36.86 ? 177 ASN   B HA   1 
ATOM   7429  H  HB2  . ASN   B 1 178 ? 30.174  30.946  50.758  1.00 41.89 ? 177 ASN   B HB2  1 
ATOM   7430  H  HB3  . ASN   B 1 178 ? 29.437  29.635  51.270  1.00 41.89 ? 177 ASN   B HB3  1 
ATOM   7431  H  HD21 . ASN   B 1 178 ? 30.272  31.066  53.266  1.00 66.72 ? 177 ASN   B HD21 1 
ATOM   7432  H  HD22 . ASN   B 1 178 ? 31.517  30.561  53.907  1.00 66.72 ? 177 ASN   B HD22 1 
ATOM   7433  N  N    . LEU   B 1 179 ? 31.724  27.058  49.379  1.00 23.45 ? 178 LEU   B N    1 
ATOM   7434  C  CA   . LEU   B 1 179 ? 31.899  25.621  49.571  1.00 27.97 ? 178 LEU   B CA   1 
ATOM   7435  C  C    . LEU   B 1 179 ? 33.262  25.296  50.178  1.00 30.38 ? 178 LEU   B C    1 
ATOM   7436  O  O    . LEU   B 1 179 ? 33.689  24.141  50.159  1.00 29.23 ? 178 LEU   B O    1 
ATOM   7437  C  CB   . LEU   B 1 179 ? 31.715  24.892  48.238  1.00 29.66 ? 178 LEU   B CB   1 
ATOM   7438  C  CG   . LEU   B 1 179 ? 30.257  24.919  47.797  1.00 22.60 ? 178 LEU   B CG   1 
ATOM   7439  C  CD1  . LEU   B 1 179 ? 30.193  24.497  46.308  1.00 28.26 ? 178 LEU   B CD1  1 
ATOM   7440  C  CD2  . LEU   B 1 179 ? 29.338  24.035  48.607  1.00 29.99 ? 178 LEU   B CD2  1 
ATOM   7441  H  H    . LEU   B 1 179 ? 32.277  27.399  48.816  1.00 28.14 ? 178 LEU   B H    1 
ATOM   7442  H  HA   . LEU   B 1 179 ? 31.224  25.296  50.187  1.00 33.57 ? 178 LEU   B HA   1 
ATOM   7443  H  HB2  . LEU   B 1 179 ? 32.252  25.327  47.557  1.00 35.59 ? 178 LEU   B HB2  1 
ATOM   7444  H  HB3  . LEU   B 1 179 ? 31.991  23.967  48.337  1.00 35.59 ? 178 LEU   B HB3  1 
ATOM   7445  H  HG   . LEU   B 1 179 ? 29.930  25.822  47.933  1.00 27.12 ? 178 LEU   B HG   1 
ATOM   7446  H  HD11 . LEU   B 1 179 ? 29.414  24.905  45.897  1.00 33.92 ? 178 LEU   B HD11 1 
ATOM   7447  H  HD12 . LEU   B 1 179 ? 30.999  24.798  45.860  1.00 33.92 ? 178 LEU   B HD12 1 
ATOM   7448  H  HD13 . LEU   B 1 179 ? 30.126  23.531  46.256  1.00 33.92 ? 178 LEU   B HD13 1 
ATOM   7449  H  HD21 . LEU   B 1 179 ? 28.451  24.058  48.216  1.00 35.98 ? 178 LEU   B HD21 1 
ATOM   7450  H  HD22 . LEU   B 1 179 ? 29.681  23.128  48.596  1.00 35.98 ? 178 LEU   B HD22 1 
ATOM   7451  H  HD23 . LEU   B 1 179 ? 29.305  24.364  49.519  1.00 35.98 ? 178 LEU   B HD23 1 
ATOM   7452  N  N    . ASP   B 1 180 ? 33.933  26.286  50.765  1.00 34.26 ? 179 ASP   B N    1 
ATOM   7453  C  CA   . ASP   B 1 180 ? 35.337  26.102  51.139  1.00 45.66 ? 179 ASP   B CA   1 
ATOM   7454  C  C    . ASP   B 1 180 ? 35.520  25.013  52.184  1.00 36.15 ? 179 ASP   B C    1 
ATOM   7455  O  O    . ASP   B 1 180 ? 36.536  24.311  52.167  1.00 42.57 ? 179 ASP   B O    1 
ATOM   7456  C  CB   . ASP   B 1 180 ? 35.939  27.414  51.653  1.00 55.04 ? 179 ASP   B CB   1 
ATOM   7457  C  CG   . ASP   B 1 180 ? 35.761  28.559  50.678  1.00 57.51 ? 179 ASP   B CG   1 
ATOM   7458  O  OD1  . ASP   B 1 180 ? 36.030  28.364  49.472  1.00 52.36 ? 179 ASP   B OD1  1 
ATOM   7459  O  OD2  . ASP   B 1 180 ? 35.328  29.642  51.122  1.00 64.97 ? 179 ASP   B OD2  1 
ATOM   7460  H  H    . ASP   B 1 180 ? 33.607  27.059  50.954  1.00 41.11 ? 179 ASP   B H    1 
ATOM   7461  H  HA   . ASP   B 1 180 ? 35.819  25.837  50.340  1.00 54.79 ? 179 ASP   B HA   1 
ATOM   7462  H  HB2  . ASP   B 1 180 ? 35.505  27.657  52.485  1.00 66.04 ? 179 ASP   B HB2  1 
ATOM   7463  H  HB3  . ASP   B 1 180 ? 36.890  27.290  51.799  1.00 66.04 ? 179 ASP   B HB3  1 
ATOM   7464  N  N    . SER   B 1 181 ? 34.562  24.859  53.095  1.00 30.08 ? 180 SER   B N    1 
ATOM   7465  C  CA   . SER   B 1 181 ? 34.650  23.848  54.141  1.00 40.18 ? 180 SER   B CA   1 
ATOM   7466  C  C    . SER   B 1 181 ? 34.309  22.439  53.652  1.00 38.30 ? 180 SER   B C    1 
ATOM   7467  O  O    . SER   B 1 181 ? 34.534  21.476  54.390  1.00 33.14 ? 180 SER   B O    1 
ATOM   7468  C  CB   . SER   B 1 181 ? 33.733  24.232  55.308  1.00 39.62 ? 180 SER   B CB   1 
ATOM   7469  O  OG   . SER   B 1 181 ? 32.411  23.759  55.120  1.00 47.94 ? 180 SER   B OG   1 
ATOM   7470  H  H    . SER   B 1 181 ? 33.845  25.333  53.128  1.00 36.09 ? 180 SER   B H    1 
ATOM   7471  H  HA   . SER   B 1 181 ? 35.561  23.820  54.472  1.00 48.22 ? 180 SER   B HA   1 
ATOM   7472  H  HB2  . SER   B 1 181 ? 34.089  23.847  56.124  1.00 47.54 ? 180 SER   B HB2  1 
ATOM   7473  H  HB3  . SER   B 1 181 ? 33.710  25.199  55.381  1.00 47.54 ? 180 SER   B HB3  1 
ATOM   7474  H  HG   . SER   B 1 181 ? 31.959  23.885  55.816  1.00 57.53 ? 180 SER   B HG   1 
ATOM   7475  N  N    . CYS   B 1 182 ? 33.816  22.276  52.426  1.00 29.28 ? 181 CYS   B N    1 
ATOM   7476  C  CA   . CYS   B 1 182 ? 33.528  20.931  51.921  1.00 24.45 ? 181 CYS   B CA   1 
ATOM   7477  C  C    . CYS   B 1 182 ? 34.810  20.120  51.784  1.00 23.83 ? 181 CYS   B C    1 
ATOM   7478  O  O    . CYS   B 1 182 ? 35.843  20.623  51.342  1.00 26.56 ? 181 CYS   B O    1 
ATOM   7479  C  CB   . CYS   B 1 182 ? 32.820  21.021  50.564  1.00 20.97 ? 181 CYS   B CB   1 
ATOM   7480  S  SG   . CYS   B 1 182 ? 31.178  21.702  50.709  1.00 25.26 ? 181 CYS   B SG   1 
ATOM   7481  H  H    . CYS   B 1 182 ? 33.642  22.914  51.876  1.00 35.13 ? 181 CYS   B H    1 
ATOM   7482  H  HA   . CYS   B 1 182 ? 32.945  20.472  52.546  1.00 29.34 ? 181 CYS   B HA   1 
ATOM   7483  H  HB2  . CYS   B 1 182 ? 33.335  21.592  49.973  1.00 25.16 ? 181 CYS   B HB2  1 
ATOM   7484  H  HB3  . CYS   B 1 182 ? 32.747  20.131  50.184  1.00 25.16 ? 181 CYS   B HB3  1 
ATOM   7485  H  HG   . CYS   B 1 182 ? 30.377  20.858  50.414  1.00 30.31 ? 181 CYS   B HG   1 
ATOM   7486  N  N    . LYS   B 1 183 ? 34.734  18.844  52.156  1.00 21.58 ? 182 LYS   B N    1 
ATOM   7487  C  CA   . LYS   B 1 183 ? 35.899  17.984  52.199  1.00 19.68 ? 182 LYS   B CA   1 
ATOM   7488  C  C    . LYS   B 1 183 ? 35.522  16.589  51.742  1.00 23.85 ? 182 LYS   B C    1 
ATOM   7489  O  O    . LYS   B 1 183 ? 34.481  16.068  52.125  1.00 21.58 ? 182 LYS   B O    1 
ATOM   7490  C  CB   . LYS   B 1 183 ? 36.478  17.922  53.630  1.00 23.72 ? 182 LYS   B CB   1 
ATOM   7491  C  CG   . LYS   B 1 183 ? 37.768  17.112  53.714  1.00 26.94 ? 182 LYS   B CG   1 
ATOM   7492  C  CD   . LYS   B 1 183 ? 38.486  17.328  55.056  1.00 31.06 ? 182 LYS   B CD   1 
ATOM   7493  C  CE   . LYS   B 1 183 ? 38.946  16.011  55.656  1.00 38.42 ? 182 LYS   B CE   1 
ATOM   7494  N  NZ   . LYS   B 1 183 ? 39.429  16.181  57.066  1.00 44.49 ? 182 LYS   B NZ   1 
ATOM   7495  H  H    . LYS   B 1 183 ? 34.005  18.453  52.390  1.00 25.89 ? 182 LYS   B H    1 
ATOM   7496  H  HA   . LYS   B 1 183 ? 36.579  18.324  51.595  1.00 23.61 ? 182 LYS   B HA   1 
ATOM   7497  H  HB2  . LYS   B 1 183 ? 36.669  18.823  53.932  1.00 28.46 ? 182 LYS   B HB2  1 
ATOM   7498  H  HB3  . LYS   B 1 183 ? 35.825  17.507  54.216  1.00 28.46 ? 182 LYS   B HB3  1 
ATOM   7499  H  HG2  . LYS   B 1 183 ? 37.560  16.168  53.628  1.00 32.32 ? 182 LYS   B HG2  1 
ATOM   7500  H  HG3  . LYS   B 1 183 ? 38.365  17.386  53.001  1.00 32.32 ? 182 LYS   B HG3  1 
ATOM   7501  H  HD2  . LYS   B 1 183 ? 39.265  17.889  54.917  1.00 37.27 ? 182 LYS   B HD2  1 
ATOM   7502  H  HD3  . LYS   B 1 183 ? 37.878  17.753  55.681  1.00 37.27 ? 182 LYS   B HD3  1 
ATOM   7503  H  HE2  . LYS   B 1 183 ? 38.205  15.385  55.662  1.00 46.10 ? 182 LYS   B HE2  1 
ATOM   7504  H  HE3  . LYS   B 1 183 ? 39.677  15.655  55.126  1.00 46.10 ? 182 LYS   B HE3  1 
ATOM   7505  H  HZ1  . LYS   B 1 183 ? 40.046  15.568  57.253  1.00 53.39 ? 182 LYS   B HZ1  1 
ATOM   7506  H  HZ2  . LYS   B 1 183 ? 39.784  16.990  57.171  1.00 53.39 ? 182 LYS   B HZ2  1 
ATOM   7507  H  HZ3  . LYS   B 1 183 ? 38.749  16.088  57.634  1.00 53.39 ? 182 LYS   B HZ3  1 
ATOM   7508  N  N    . ARG   B 1 184 ? 36.381  15.988  50.923  1.00 21.17 ? 183 ARG   B N    1 
ATOM   7509  C  CA   . ARG   B 1 184 ? 36.228  14.621  50.456  1.00 19.98 ? 183 ARG   B CA   1 
ATOM   7510  C  C    . ARG   B 1 184 ? 37.553  13.905  50.671  1.00 24.76 ? 183 ARG   B C    1 
ATOM   7511  O  O    . ARG   B 1 184 ? 38.607  14.439  50.315  1.00 24.82 ? 183 ARG   B O    1 
ATOM   7512  C  CB   . ARG   B 1 184 ? 35.863  14.589  48.969  1.00 20.24 ? 183 ARG   B CB   1 
ATOM   7513  C  CG   . ARG   B 1 184 ? 35.884  13.201  48.352  1.00 22.58 ? 183 ARG   B CG   1 
ATOM   7514  C  CD   . ARG   B 1 184 ? 35.311  13.233  46.956  1.00 21.06 ? 183 ARG   B CD   1 
ATOM   7515  N  NE   . ARG   B 1 184 ? 33.860  13.223  47.006  1.00 18.21 ? 183 ARG   B NE   1 
ATOM   7516  C  CZ   . ARG   B 1 184 ? 33.052  13.600  46.026  1.00 26.62 ? 183 ARG   B CZ   1 
ATOM   7517  N  NH1  . ARG   B 1 184 ? 33.509  13.854  44.816  1.00 27.23 ? 183 ARG   B NH1  1 
ATOM   7518  N  NH2  . ARG   B 1 184 ? 31.748  13.682  46.263  1.00 29.64 ? 183 ARG   B NH2  1 
ATOM   7519  H  H    . ARG   B 1 184 ? 37.087  16.370  50.613  1.00 25.40 ? 183 ARG   B H    1 
ATOM   7520  H  HA   . ARG   B 1 184 ? 35.529  14.170  50.956  1.00 23.97 ? 183 ARG   B HA   1 
ATOM   7521  H  HB2  . ARG   B 1 184 ? 34.967  14.945  48.861  1.00 24.29 ? 183 ARG   B HB2  1 
ATOM   7522  H  HB3  . ARG   B 1 184 ? 36.499  15.137  48.482  1.00 24.29 ? 183 ARG   B HB3  1 
ATOM   7523  H  HG2  . ARG   B 1 184 ? 36.799  12.881  48.303  1.00 27.09 ? 183 ARG   B HG2  1 
ATOM   7524  H  HG3  . ARG   B 1 184 ? 35.350  12.597  48.892  1.00 27.09 ? 183 ARG   B HG3  1 
ATOM   7525  H  HD2  . ARG   B 1 184 ? 35.600  14.042  46.504  1.00 25.27 ? 183 ARG   B HD2  1 
ATOM   7526  H  HD3  . ARG   B 1 184 ? 35.610  12.453  46.463  1.00 25.27 ? 183 ARG   B HD3  1 
ATOM   7527  H  HE   . ARG   B 1 184 ? 33.493  12.950  47.735  1.00 21.85 ? 183 ARG   B HE   1 
ATOM   7528  H  HH11 . ARG   B 1 184 ? 34.349  13.776  44.649  1.00 32.67 ? 183 ARG   B HH11 1 
ATOM   7529  H  HH12 . ARG   B 1 184 ? 32.967  14.097  44.194  1.00 32.67 ? 183 ARG   B HH12 1 
ATOM   7530  H  HH21 . ARG   B 1 184 ? 31.440  13.492  47.043  1.00 35.56 ? 183 ARG   B HH21 1 
ATOM   7531  H  HH22 . ARG   B 1 184 ? 31.212  13.925  45.636  1.00 35.56 ? 183 ARG   B HH22 1 
ATOM   7532  N  N    . VAL   B 1 185 ? 37.505  12.716  51.270  1.00 21.64 ? 184 VAL   B N    1 
ATOM   7533  C  CA   . VAL   B 1 185 ? 38.660  11.831  51.374  1.00 20.60 ? 184 VAL   B CA   1 
ATOM   7534  C  C    . VAL   B 1 185 ? 38.365  10.564  50.583  1.00 22.27 ? 184 VAL   B C    1 
ATOM   7535  O  O    . VAL   B 1 185 ? 37.304  9.946   50.749  1.00 22.65 ? 184 VAL   B O    1 
ATOM   7536  C  CB   . VAL   B 1 185 ? 39.008  11.497  52.840  1.00 25.76 ? 184 VAL   B CB   1 
ATOM   7537  C  CG1  . VAL   B 1 185 ? 40.279  10.626  52.913  1.00 26.41 ? 184 VAL   B CG1  1 
ATOM   7538  C  CG2  . VAL   B 1 185 ? 39.211  12.750  53.644  1.00 26.14 ? 184 VAL   B CG2  1 
ATOM   7539  H  H    . VAL   B 1 185 ? 36.795  12.394  51.632  1.00 25.97 ? 184 VAL   B H    1 
ATOM   7540  H  HA   . VAL   B 1 185 ? 39.429  12.270  50.978  1.00 24.72 ? 184 VAL   B HA   1 
ATOM   7541  H  HB   . VAL   B 1 185 ? 38.265  11.002  53.219  1.00 30.91 ? 184 VAL   B HB   1 
ATOM   7542  H  HG11 . VAL   B 1 185 ? 40.646  10.677  53.810  1.00 31.69 ? 184 VAL   B HG11 1 
ATOM   7543  H  HG12 . VAL   B 1 185 ? 40.045  9.708   52.704  1.00 31.69 ? 184 VAL   B HG12 1 
ATOM   7544  H  HG13 . VAL   B 1 185 ? 40.926  10.957  52.271  1.00 31.69 ? 184 VAL   B HG13 1 
ATOM   7545  H  HG21 . VAL   B 1 185 ? 39.775  12.548  54.407  1.00 31.37 ? 184 VAL   B HG21 1 
ATOM   7546  H  HG22 . VAL   B 1 185 ? 39.638  13.418  53.085  1.00 31.37 ? 184 VAL   B HG22 1 
ATOM   7547  H  HG23 . VAL   B 1 185 ? 38.349  13.075  53.947  1.00 31.37 ? 184 VAL   B HG23 1 
ATOM   7548  N  N    . LEU   B 1 186 ? 39.286  10.209  49.687  1.00 23.80 ? 185 LEU   B N    1 
ATOM   7549  C  CA   . LEU   B 1 186 ? 39.193  9.046   48.826  1.00 23.67 ? 185 LEU   B CA   1 
ATOM   7550  C  C    . LEU   B 1 186 ? 40.373  8.124   49.107  1.00 24.08 ? 185 LEU   B C    1 
ATOM   7551  O  O    . LEU   B 1 186 ? 41.472  8.588   49.424  1.00 24.81 ? 185 LEU   B O    1 
ATOM   7552  C  CB   . LEU   B 1 186 ? 39.245  9.469   47.326  1.00 25.32 ? 185 LEU   B CB   1 
ATOM   7553  C  CG   . LEU   B 1 186 ? 38.102  10.315  46.766  1.00 34.89 ? 185 LEU   B CG   1 
ATOM   7554  C  CD1  . LEU   B 1 186 ? 38.239  10.499  45.265  1.00 38.01 ? 185 LEU   B CD1  1 
ATOM   7555  C  CD2  . LEU   B 1 186 ? 36.780  9.702   47.121  1.00 31.49 ? 185 LEU   B CD2  1 
ATOM   7556  H  H    . LEU   B 1 186 ? 40.010  10.655  49.558  1.00 28.56 ? 185 LEU   B H    1 
ATOM   7557  H  HA   . LEU   B 1 186 ? 38.364  8.572   48.996  1.00 28.40 ? 185 LEU   B HA   1 
ATOM   7558  H  HB2  . LEU   B 1 186 ? 40.058  9.982   47.195  1.00 30.38 ? 185 LEU   B HB2  1 
ATOM   7559  H  HB3  . LEU   B 1 186 ? 39.274  8.658   46.795  1.00 30.38 ? 185 LEU   B HB3  1 
ATOM   7560  H  HG   . LEU   B 1 186 ? 38.140  11.198  47.165  1.00 41.87 ? 185 LEU   B HG   1 
ATOM   7561  H  HD11 . LEU   B 1 186 ? 37.421  10.889  44.919  1.00 45.61 ? 185 LEU   B HD11 1 
ATOM   7562  H  HD12 . LEU   B 1 186 ? 38.988  11.089  45.086  1.00 45.61 ? 185 LEU   B HD12 1 
ATOM   7563  H  HD13 . LEU   B 1 186 ? 38.394  9.635   44.853  1.00 45.61 ? 185 LEU   B HD13 1 
ATOM   7564  H  HD21 . LEU   B 1 186 ? 36.102  10.042  46.516  1.00 37.79 ? 185 LEU   B HD21 1 
ATOM   7565  H  HD22 . LEU   B 1 186 ? 36.845  8.738   47.036  1.00 37.79 ? 185 LEU   B HD22 1 
ATOM   7566  H  HD23 . LEU   B 1 186 ? 36.557  9.940   48.034  1.00 37.79 ? 185 LEU   B HD23 1 
ATOM   7567  N  N    . ASN   B 1 187 ? 40.173  6.821   48.943  1.00 25.51 ? 186 ASN   B N    1 
ATOM   7568  C  CA   . ASN   B 1 187 ? 41.283  5.881   48.985  1.00 25.80 ? 186 ASN   B CA   1 
ATOM   7569  C  C    . ASN   B 1 187 ? 41.285  5.069   47.698  1.00 26.14 ? 186 ASN   B C    1 
ATOM   7570  O  O    . ASN   B 1 187 ? 40.227  4.682   47.187  1.00 26.48 ? 186 ASN   B O    1 
ATOM   7571  C  CB   . ASN   B 1 187 ? 41.212  4.966   50.213  1.00 25.00 ? 186 ASN   B CB   1 
ATOM   7572  C  CG   . ASN   B 1 187 ? 42.534  4.266   50.483  1.00 29.07 ? 186 ASN   B CG   1 
ATOM   7573  O  OD1  . ASN   B 1 187 ? 43.614  4.795   50.161  1.00 26.72 ? 186 ASN   B OD1  1 
ATOM   7574  N  ND2  . ASN   B 1 187 ? 42.467  3.112   51.147  1.00 29.17 ? 186 ASN   B ND2  1 
ATOM   7575  H  H    . ASN   B 1 187 ? 39.404  6.461   48.806  1.00 30.61 ? 186 ASN   B H    1 
ATOM   7576  H  HA   . ASN   B 1 187 ? 42.123  6.362   49.046  1.00 30.96 ? 186 ASN   B HA   1 
ATOM   7577  H  HB2  . ASN   B 1 187 ? 40.986  5.497   50.993  1.00 30.00 ? 186 ASN   B HB2  1 
ATOM   7578  H  HB3  . ASN   B 1 187 ? 40.535  4.288   50.066  1.00 30.00 ? 186 ASN   B HB3  1 
ATOM   7579  H  HD21 . ASN   B 1 187 ? 43.186  2.676   51.326  1.00 35.00 ? 186 ASN   B HD21 1 
ATOM   7580  H  HD22 . ASN   B 1 187 ? 41.704  2.804   51.398  1.00 35.00 ? 186 ASN   B HD22 1 
ATOM   7581  N  N    . VAL   B 1 188 ? 42.475  4.876   47.144  1.00 26.39 ? 187 VAL   B N    1 
ATOM   7582  C  CA   . VAL   B 1 188 ? 42.665  4.098   45.933  1.00 24.31 ? 187 VAL   B CA   1 
ATOM   7583  C  C    . VAL   B 1 188 ? 43.584  2.942   46.288  1.00 29.28 ? 187 VAL   B C    1 
ATOM   7584  O  O    . VAL   B 1 188 ? 44.670  3.148   46.843  1.00 28.74 ? 187 VAL   B O    1 
ATOM   7585  C  CB   . VAL   B 1 188 ? 43.253  4.954   44.797  1.00 28.43 ? 187 VAL   B CB   1 
ATOM   7586  C  CG1  . VAL   B 1 188 ? 43.559  4.086   43.585  1.00 31.15 ? 187 VAL   B CG1  1 
ATOM   7587  C  CG2  . VAL   B 1 188 ? 42.326  6.083   44.439  1.00 30.06 ? 187 VAL   B CG2  1 
ATOM   7588  H  H    . VAL   B 1 188 ? 43.207  5.196   47.462  1.00 31.67 ? 187 VAL   B H    1 
ATOM   7589  H  HA   . VAL   B 1 188 ? 41.818  3.741   45.623  1.00 29.18 ? 187 VAL   B HA   1 
ATOM   7590  H  HB   . VAL   B 1 188 ? 44.085  5.349   45.100  1.00 34.11 ? 187 VAL   B HB   1 
ATOM   7591  H  HG11 . VAL   B 1 188 ? 43.658  4.655   42.806  1.00 37.38 ? 187 VAL   B HG11 1 
ATOM   7592  H  HG12 . VAL   B 1 188 ? 44.383  3.599   43.745  1.00 37.38 ? 187 VAL   B HG12 1 
ATOM   7593  H  HG13 . VAL   B 1 188 ? 42.828  3.463   43.449  1.00 37.38 ? 187 VAL   B HG13 1 
ATOM   7594  H  HG21 . VAL   B 1 188 ? 42.448  6.308   43.503  1.00 36.07 ? 187 VAL   B HG21 1 
ATOM   7595  H  HG22 . VAL   B 1 188 ? 41.411  5.802   44.594  1.00 36.07 ? 187 VAL   B HG22 1 
ATOM   7596  H  HG23 . VAL   B 1 188 ? 42.535  6.851   44.993  1.00 36.07 ? 187 VAL   B HG23 1 
ATOM   7597  N  N    . VAL   B 1 189 ? 43.176  1.738   45.945  1.00 29.93 ? 188 VAL   B N    1 
ATOM   7598  C  CA   . VAL   B 1 189 ? 43.899  0.542   46.342  1.00 30.98 ? 188 VAL   B CA   1 
ATOM   7599  C  C    . VAL   B 1 189 ? 44.235  -0.215  45.062  1.00 34.94 ? 188 VAL   B C    1 
ATOM   7600  O  O    . VAL   B 1 189 ? 43.341  -0.686  44.357  1.00 39.20 ? 188 VAL   B O    1 
ATOM   7601  C  CB   . VAL   B 1 189 ? 43.084  -0.306  47.323  1.00 27.01 ? 188 VAL   B CB   1 
ATOM   7602  C  CG1  . VAL   B 1 189 ? 43.809  -1.606  47.733  1.00 38.30 ? 188 VAL   B CG1  1 
ATOM   7603  C  CG2  . VAL   B 1 189 ? 42.738  0.495   48.576  1.00 37.19 ? 188 VAL   B CG2  1 
ATOM   7604  H  H    . VAL   B 1 189 ? 42.472  1.583   45.476  1.00 35.91 ? 188 VAL   B H    1 
ATOM   7605  H  HA   . VAL   B 1 189 ? 44.737  0.782   46.767  1.00 37.18 ? 188 VAL   B HA   1 
ATOM   7606  H  HB   . VAL   B 1 189 ? 42.269  -0.558  46.862  1.00 32.41 ? 188 VAL   B HB   1 
ATOM   7607  H  HG11 . VAL   B 1 189 ? 43.477  -1.894  48.598  1.00 45.96 ? 188 VAL   B HG11 1 
ATOM   7608  H  HG12 . VAL   B 1 189 ? 43.634  -2.289  47.068  1.00 45.96 ? 188 VAL   B HG12 1 
ATOM   7609  H  HG13 . VAL   B 1 189 ? 44.762  -1.433  47.786  1.00 45.96 ? 188 VAL   B HG13 1 
ATOM   7610  H  HG21 . VAL   B 1 189 ? 42.513  -0.119  49.292  1.00 44.62 ? 188 VAL   B HG21 1 
ATOM   7611  H  HG22 . VAL   B 1 189 ? 43.505  1.032   48.829  1.00 44.62 ? 188 VAL   B HG22 1 
ATOM   7612  H  HG23 . VAL   B 1 189 ? 41.981  1.071   48.383  1.00 44.62 ? 188 VAL   B HG23 1 
ATOM   7613  N  N    . CYS   B 1 190 ? 45.528  -0.275  44.749  1.00 41.18 ? 189 CYS   B N    1 
ATOM   7614  C  CA   . CYS   B 1 190 ? 46.026  -1.084  43.644  1.00 44.77 ? 189 CYS   B CA   1 
ATOM   7615  C  C    . CYS   B 1 190 ? 46.621  -2.345  44.276  1.00 46.07 ? 189 CYS   B C    1 
ATOM   7616  O  O    . CYS   B 1 190 ? 47.345  -2.266  45.274  1.00 41.28 ? 189 CYS   B O    1 
ATOM   7617  C  CB   . CYS   B 1 190 ? 47.097  -0.383  42.804  1.00 43.51 ? 189 CYS   B CB   1 
ATOM   7618  S  SG   . CYS   B 1 190 ? 47.862  -1.640  41.703  1.00 49.18 ? 189 CYS   B SG   1 
ATOM   7619  H  H    . CYS   B 1 190 ? 46.144  0.152   45.170  1.00 49.41 ? 189 CYS   B H    1 
ATOM   7620  H  HA   . CYS   B 1 190 ? 45.299  -1.286  43.034  1.00 53.73 ? 189 CYS   B HA   1 
ATOM   7621  N  N    . LYS   B 1 191 ? 46.347  -3.516  43.703  1.00 54.96 ? 190 LYS   B N    1 
ATOM   7622  C  CA   . LYS   B 1 191 ? 46.861  -4.742  44.302  1.00 58.87 ? 190 LYS   B CA   1 
ATOM   7623  C  C    . LYS   B 1 191 ? 48.384  -4.764  44.377  1.00 56.93 ? 190 LYS   B C    1 
ATOM   7624  O  O    . LYS   B 1 191 ? 48.958  -5.487  45.204  1.00 57.69 ? 190 LYS   B O    1 
ATOM   7625  C  CB   . LYS   B 1 191 ? 46.356  -5.934  43.496  1.00 68.66 ? 190 LYS   B CB   1 
ATOM   7626  H  H    . LYS   B 1 191 ? 45.880  -3.623  42.989  1.00 65.95 ? 190 LYS   B H    1 
ATOM   7627  H  HA   . LYS   B 1 191 ? 46.531  -4.817  45.212  1.00 70.65 ? 190 LYS   B HA   1 
ATOM   7628  N  N    . THR   B 1 192 ? 49.039  -4.025  43.512  1.00 54.20 ? 191 THR   B N    1 
ATOM   7629  C  CA   . THR   B 1 192 ? 50.476  -3.991  43.511  1.00 57.18 ? 191 THR   B CA   1 
ATOM   7630  C  C    . THR   B 1 192 ? 51.108  -2.705  44.022  1.00 55.45 ? 191 THR   B C    1 
ATOM   7631  O  O    . THR   B 1 192 ? 52.096  -2.751  44.708  1.00 58.78 ? 191 THR   B O    1 
ATOM   7632  C  CB   . THR   B 1 192 ? 51.047  -4.388  42.118  1.00 66.06 ? 191 THR   B CB   1 
ATOM   7633  H  H    . THR   B 1 192 ? 48.665  -3.551  42.901  1.00 65.04 ? 191 THR   B H    1 
ATOM   7634  H  HA   . THR   B 1 192 ? 50.772  -4.692  44.129  1.00 68.62 ? 191 THR   B HA   1 
ATOM   7635  N  N    . CYS   B 1 193 ? 50.534  -1.564  43.711  1.00 54.30 ? 192 CYS   B N    1 
ATOM   7636  C  CA   . CYS   B 1 193 ? 51.085  -0.300  44.101  1.00 52.76 ? 192 CYS   B CA   1 
ATOM   7637  C  C    . CYS   B 1 193 ? 50.718  0.122   45.529  1.00 47.83 ? 192 CYS   B C    1 
ATOM   7638  O  O    . CYS   B 1 193 ? 51.200  1.113   45.996  1.00 54.96 ? 192 CYS   B O    1 
ATOM   7639  C  CB   . CYS   B 1 193 ? 50.669  0.771   43.096  1.00 44.37 ? 192 CYS   B CB   1 
ATOM   7640  H  H    . CYS   B 1 193 ? 49.815  -1.479  43.255  1.00 65.16 ? 192 CYS   B H    1 
ATOM   7641  H  HA   . CYS   B 1 193 ? 52.062  -0.368  44.063  1.00 63.31 ? 192 CYS   B HA   1 
ATOM   7642  N  N    . GLY   B 1 194 ? 49.902  -0.629  46.233  1.00 46.99 ? 193 GLY   B N    1 
ATOM   7643  C  CA   . GLY   B 1 194 ? 49.522  -0.244  47.569  1.00 46.28 ? 193 GLY   B CA   1 
ATOM   7644  C  C    . GLY   B 1 194 ? 48.292  0.637   47.514  1.00 41.72 ? 193 GLY   B C    1 
ATOM   7645  O  O    . GLY   B 1 194 ? 47.473  0.579   46.590  1.00 41.45 ? 193 GLY   B O    1 
ATOM   7646  H  H    . GLY   B 1 194 ? 49.578  -1.376  45.958  1.00 56.39 ? 193 GLY   B H    1 
ATOM   7647  H  HA2  . GLY   B 1 194 ? 49.324  -1.033  48.097  1.00 55.54 ? 193 GLY   B HA2  1 
ATOM   7648  H  HA3  . GLY   B 1 194 ? 50.245  0.246   47.992  1.00 55.54 ? 193 GLY   B HA3  1 
ATOM   7649  N  N    . GLN   B 1 195 ? 48.149  1.445   48.550  1.00 40.27 ? 194 GLN   B N    1 
ATOM   7650  C  CA   . GLN   B 1 195 ? 46.989  2.306   48.700  1.00 35.34 ? 194 GLN   B CA   1 
ATOM   7651  C  C    . GLN   B 1 195 ? 47.439  3.753   48.783  1.00 31.78 ? 194 GLN   B C    1 
ATOM   7652  O  O    . GLN   B 1 195 ? 48.571  4.050   49.177  1.00 32.44 ? 194 GLN   B O    1 
ATOM   7653  C  CB   . GLN   B 1 195 ? 46.165  1.930   49.921  1.00 32.68 ? 194 GLN   B CB   1 
ATOM   7654  C  CG   . GLN   B 1 195 ? 46.938  1.773   51.188  1.00 35.22 ? 194 GLN   B CG   1 
ATOM   7655  C  CD   . GLN   B 1 195 ? 46.022  1.557   52.391  1.00 44.87 ? 194 GLN   B CD   1 
ATOM   7656  O  OE1  . GLN   B 1 195 ? 44.787  1.643   52.286  1.00 35.93 ? 194 GLN   B OE1  1 
ATOM   7657  N  NE2  . GLN   B 1 195 ? 46.623  1.250   53.535  1.00 34.96 ? 194 GLN   B NE2  1 
ATOM   7658  H  H    . GLN   B 1 195 ? 48.720  1.515   49.190  1.00 48.33 ? 194 GLN   B H    1 
ATOM   7659  H  HA   . GLN   B 1 195 ? 46.412  2.215   47.925  1.00 42.41 ? 194 GLN   B HA   1 
ATOM   7660  H  HB2  . GLN   B 1 195 ? 45.504  2.624   50.069  1.00 39.21 ? 194 GLN   B HB2  1 
ATOM   7661  H  HB3  . GLN   B 1 195 ? 45.724  1.084   49.743  1.00 39.21 ? 194 GLN   B HB3  1 
ATOM   7662  H  HG2  . GLN   B 1 195 ? 47.524  1.004   51.111  1.00 42.26 ? 194 GLN   B HG2  1 
ATOM   7663  H  HG3  . GLN   B 1 195 ? 47.461  2.574   51.345  1.00 42.26 ? 194 GLN   B HG3  1 
ATOM   7664  H  HE21 . GLN   B 1 195 ? 47.480  1.183   53.566  1.00 41.95 ? 194 GLN   B HE21 1 
ATOM   7665  H  HE22 . GLN   B 1 195 ? 46.155  1.118   54.244  1.00 41.95 ? 194 GLN   B HE22 1 
ATOM   7666  N  N    . GLN   B 1 196 ? 46.579  4.653   48.325  1.00 26.92 ? 195 GLN   B N    1 
ATOM   7667  C  CA   . GLN   B 1 196 ? 46.896  6.074   48.381  1.00 27.50 ? 195 GLN   B CA   1 
ATOM   7668  C  C    . GLN   B 1 196 ? 45.624  6.844   48.687  1.00 26.51 ? 195 GLN   B C    1 
ATOM   7669  O  O    . GLN   B 1 196 ? 44.639  6.741   47.950  1.00 24.28 ? 195 GLN   B O    1 
ATOM   7670  C  CB   . GLN   B 1 196 ? 47.511  6.559   47.076  1.00 28.01 ? 195 GLN   B CB   1 
ATOM   7671  C  CG   . GLN   B 1 196 ? 47.904  8.011   47.114  1.00 26.58 ? 195 GLN   B CG   1 
ATOM   7672  C  CD   . GLN   B 1 196 ? 48.861  8.308   48.238  1.00 38.12 ? 195 GLN   B CD   1 
ATOM   7673  O  OE1  . GLN   B 1 196 ? 49.842  7.585   48.451  1.00 31.89 ? 195 GLN   B OE1  1 
ATOM   7674  N  NE2  . GLN   B 1 196 ? 48.614  9.404   48.941  1.00 38.11 ? 195 GLN   B NE2  1 
ATOM   7675  H  H    . GLN   B 1 196 ? 45.813  4.468   47.980  1.00 32.30 ? 195 GLN   B H    1 
ATOM   7676  H  HA   . GLN   B 1 196 ? 47.532  6.233   49.096  1.00 33.00 ? 195 GLN   B HA   1 
ATOM   7677  H  HB2  . GLN   B 1 196 ? 48.309  6.038   46.892  1.00 33.62 ? 195 GLN   B HB2  1 
ATOM   7678  H  HB3  . GLN   B 1 196 ? 46.866  6.442   46.362  1.00 33.62 ? 195 GLN   B HB3  1 
ATOM   7679  H  HG2  . GLN   B 1 196 ? 48.336  8.247   46.278  1.00 31.89 ? 195 GLN   B HG2  1 
ATOM   7680  H  HG3  . GLN   B 1 196 ? 47.110  8.554   47.240  1.00 31.89 ? 195 GLN   B HG3  1 
ATOM   7681  H  HE21 . GLN   B 1 196 ? 47.939  9.899   48.743  1.00 45.74 ? 195 GLN   B HE21 1 
ATOM   7682  H  HE22 . GLN   B 1 196 ? 49.129  9.621   49.595  1.00 45.74 ? 195 GLN   B HE22 1 
ATOM   7683  N  N    . GLN   B 1 197 ? 45.666  7.634   49.750  1.00 26.74 ? 196 GLN   B N    1 
ATOM   7684  C  CA   . GLN   B 1 197 ? 44.535  8.458   50.143  1.00 28.49 ? 196 GLN   B CA   1 
ATOM   7685  C  C    . GLN   B 1 197 ? 44.708  9.840   49.547  1.00 26.53 ? 196 GLN   B C    1 
ATOM   7686  O  O    . GLN   B 1 197 ? 45.826  10.335  49.414  1.00 26.14 ? 196 GLN   B O    1 
ATOM   7687  C  CB   . GLN   B 1 197 ? 44.451  8.548   51.670  1.00 30.89 ? 196 GLN   B CB   1 
ATOM   7688  C  CG   . GLN   B 1 197 ? 43.175  9.157   52.210  1.00 27.76 ? 196 GLN   B CG   1 
ATOM   7689  C  CD   . GLN   B 1 197 ? 43.162  9.182   53.727  1.00 25.90 ? 196 GLN   B CD   1 
ATOM   7690  O  OE1  . GLN   B 1 197 ? 42.682  8.245   54.369  1.00 30.20 ? 196 GLN   B OE1  1 
ATOM   7691  N  NE2  . GLN   B 1 197 ? 43.647  10.268  54.300  1.00 32.09 ? 196 GLN   B NE2  1 
ATOM   7692  H  H    . GLN   B 1 197 ? 46.349  7.711   50.267  1.00 32.09 ? 196 GLN   B H    1 
ATOM   7693  H  HA   . GLN   B 1 197 ? 43.704  8.075   49.821  1.00 34.18 ? 196 GLN   B HA   1 
ATOM   7694  H  HB2  . GLN   B 1 197 ? 44.521  7.652   52.034  1.00 37.07 ? 196 GLN   B HB2  1 
ATOM   7695  H  HB3  . GLN   B 1 197 ? 45.189  9.093   51.986  1.00 37.07 ? 196 GLN   B HB3  1 
ATOM   7696  H  HG2  . GLN   B 1 197 ? 43.095  10.069  51.890  1.00 33.31 ? 196 GLN   B HG2  1 
ATOM   7697  H  HG3  . GLN   B 1 197 ? 42.417  8.632   51.908  1.00 33.31 ? 196 GLN   B HG3  1 
ATOM   7698  H  HE21 . GLN   B 1 197 ? 43.948  10.912  53.815  1.00 38.51 ? 196 GLN   B HE21 1 
ATOM   7699  H  HE22 . GLN   B 1 197 ? 43.662  10.331  55.157  1.00 38.51 ? 196 GLN   B HE22 1 
ATOM   7700  N  N    . THR   B 1 198 ? 43.597  10.439  49.142  1.00 23.18 ? 197 THR   B N    1 
ATOM   7701  C  CA   . THR   B 1 198 ? 43.584  11.800  48.640  1.00 29.57 ? 197 THR   B CA   1 
ATOM   7702  C  C    . THR   B 1 198 ? 42.458  12.560  49.318  1.00 28.36 ? 197 THR   B C    1 
ATOM   7703  O  O    . THR   B 1 198 ? 41.376  12.005  49.543  1.00 25.75 ? 197 THR   B O    1 
ATOM   7704  C  CB   . THR   B 1 198 ? 43.365  11.830  47.136  1.00 27.77 ? 197 THR   B CB   1 
ATOM   7705  O  OG1  . THR   B 1 198 ? 44.486  11.223  46.495  1.00 37.78 ? 197 THR   B OG1  1 
ATOM   7706  C  CG2  . THR   B 1 198 ? 43.218  13.283  46.667  1.00 33.24 ? 197 THR   B CG2  1 
ATOM   7707  H  H    . THR   B 1 198 ? 42.822  10.067  49.149  1.00 27.82 ? 197 THR   B H    1 
ATOM   7708  H  HA   . THR   B 1 198 ? 44.429  12.231  48.840  1.00 35.49 ? 197 THR   B HA   1 
ATOM   7709  H  HB   . THR   B 1 198 ? 42.558  11.348  46.894  1.00 33.33 ? 197 THR   B HB   1 
ATOM   7710  H  HG1  . THR   B 1 198 ? 44.342  11.151  45.670  1.00 45.33 ? 197 THR   B HG1  1 
ATOM   7711  H  HG21 . THR   B 1 198 ? 43.421  13.349  45.721  1.00 39.89 ? 197 THR   B HG21 1 
ATOM   7712  H  HG22 . THR   B 1 198 ? 42.310  13.590  46.816  1.00 39.89 ? 197 THR   B HG22 1 
ATOM   7713  H  HG23 . THR   B 1 198 ? 43.828  13.854  47.161  1.00 39.89 ? 197 THR   B HG23 1 
ATOM   7714  N  N    . THR   B 1 199 ? 42.713  13.828  49.628  1.00 25.07 ? 198 THR   B N    1 
ATOM   7715  C  CA   . THR   B 1 199 ? 41.721  14.719  50.204  1.00 27.76 ? 198 THR   B CA   1 
ATOM   7716  C  C    . THR   B 1 199 ? 41.478  15.856  49.229  1.00 30.84 ? 198 THR   B C    1 
ATOM   7717  O  O    . THR   B 1 199 ? 42.431  16.464  48.736  1.00 27.28 ? 198 THR   B O    1 
ATOM   7718  C  CB   . THR   B 1 199 ? 42.181  15.269  51.550  1.00 33.20 ? 198 THR   B CB   1 
ATOM   7719  O  OG1  . THR   B 1 199 ? 42.387  14.184  52.466  1.00 33.56 ? 198 THR   B OG1  1 
ATOM   7720  C  CG2  . THR   B 1 199 ? 41.147  16.235  52.117  1.00 32.59 ? 198 THR   B CG2  1 
ATOM   7721  H  H    . THR   B 1 199 ? 43.478  14.203  49.508  1.00 30.08 ? 198 THR   B H    1 
ATOM   7722  H  HA   . THR   B 1 199 ? 40.890  14.239  50.348  1.00 33.31 ? 198 THR   B HA   1 
ATOM   7723  H  HB   . THR   B 1 199 ? 43.014  15.754  51.436  1.00 39.84 ? 198 THR   B HB   1 
ATOM   7724  H  HG1  . THR   B 1 199 ? 41.784  13.608  52.369  1.00 40.27 ? 198 THR   B HG1  1 
ATOM   7725  H  HG21 . THR   B 1 199 ? 41.265  16.321  53.076  1.00 39.10 ? 198 THR   B HG21 1 
ATOM   7726  H  HG22 . THR   B 1 199 ? 41.250  17.109  51.708  1.00 39.10 ? 198 THR   B HG22 1 
ATOM   7727  H  HG23 . THR   B 1 199 ? 40.253  15.907  51.938  1.00 39.10 ? 198 THR   B HG23 1 
ATOM   7728  N  N    . LEU   B 1 200 ? 40.210  16.088  48.895  1.00 25.23 ? 199 LEU   B N    1 
ATOM   7729  C  CA   . LEU   B 1 200 ? 39.800  17.188  48.037  1.00 24.34 ? 199 LEU   B CA   1 
ATOM   7730  C  C    . LEU   B 1 200 ? 39.030  18.190  48.888  1.00 28.41 ? 199 LEU   B C    1 
ATOM   7731  O  O    . LEU   B 1 200 ? 38.414  17.833  49.895  1.00 23.94 ? 199 LEU   B O    1 
ATOM   7732  C  CB   . LEU   B 1 200 ? 38.941  16.699  46.870  1.00 26.86 ? 199 LEU   B CB   1 
ATOM   7733  C  CG   . LEU   B 1 200 ? 39.521  15.546  46.053  1.00 30.58 ? 199 LEU   B CG   1 
ATOM   7734  C  CD1  . LEU   B 1 200 ? 38.550  15.047  45.002  1.00 36.05 ? 199 LEU   B CD1  1 
ATOM   7735  C  CD2  . LEU   B 1 200 ? 40.825  16.007  45.404  1.00 29.40 ? 199 LEU   B CD2  1 
ATOM   7736  H  H    . LEU   B 1 200 ? 39.552  15.604  49.164  1.00 30.28 ? 199 LEU   B H    1 
ATOM   7737  H  HA   . LEU   B 1 200 ? 40.573  17.628  47.649  1.00 29.21 ? 199 LEU   B HA   1 
ATOM   7738  H  HB2  . LEU   B 1 200 ? 38.089  16.400  47.225  1.00 32.23 ? 199 LEU   B HB2  1 
ATOM   7739  H  HB3  . LEU   B 1 200 ? 38.804  17.443  46.262  1.00 32.23 ? 199 LEU   B HB3  1 
ATOM   7740  H  HG   . LEU   B 1 200 ? 39.696  14.796  46.642  1.00 36.70 ? 199 LEU   B HG   1 
ATOM   7741  H  HD11 . LEU   B 1 200 ? 38.965  14.325  44.505  1.00 43.26 ? 199 LEU   B HD11 1 
ATOM   7742  H  HD12 . LEU   B 1 200 ? 37.746  14.727  45.441  1.00 43.26 ? 199 LEU   B HD12 1 
ATOM   7743  H  HD13 . LEU   B 1 200 ? 38.330  15.778  44.402  1.00 43.26 ? 199 LEU   B HD13 1 
ATOM   7744  H  HD21 . LEU   B 1 200 ? 40.945  15.534  44.566  1.00 35.28 ? 199 LEU   B HD21 1 
ATOM   7745  H  HD22 . LEU   B 1 200 ? 40.776  16.962  45.240  1.00 35.28 ? 199 LEU   B HD22 1 
ATOM   7746  H  HD23 . LEU   B 1 200 ? 41.562  15.812  46.003  1.00 35.28 ? 199 LEU   B HD23 1 
ATOM   7747  N  N    . LYS   B 1 201 ? 39.045  19.446  48.465  1.00 26.07 ? 200 LYS   B N    1 
ATOM   7748  C  CA   . LYS   B 1 201 ? 38.343  20.475  49.203  1.00 25.79 ? 200 LYS   B CA   1 
ATOM   7749  C  C    . LYS   B 1 201 ? 37.585  21.355  48.226  1.00 34.46 ? 200 LYS   B C    1 
ATOM   7750  O  O    . LYS   B 1 201 ? 37.891  21.404  47.030  1.00 31.75 ? 200 LYS   B O    1 
ATOM   7751  C  CB   . LYS   B 1 201 ? 39.292  21.359  50.044  1.00 33.01 ? 200 LYS   B CB   1 
ATOM   7752  C  CG   . LYS   B 1 201 ? 40.106  20.630  51.116  1.00 38.62 ? 200 LYS   B CG   1 
ATOM   7753  C  CD   . LYS   B 1 201 ? 39.255  20.121  52.254  1.00 40.63 ? 200 LYS   B CD   1 
ATOM   7754  C  CE   . LYS   B 1 201 ? 38.471  21.235  52.970  1.00 43.68 ? 200 LYS   B CE   1 
ATOM   7755  N  NZ   . LYS   B 1 201 ? 39.311  22.415  53.306  1.00 58.13 ? 200 LYS   B NZ   1 
ATOM   7756  H  H    . LYS   B 1 201 ? 39.453  19.722  47.759  1.00 31.28 ? 200 LYS   B H    1 
ATOM   7757  H  HA   . LYS   B 1 201 ? 37.716  20.045  49.804  1.00 30.95 ? 200 LYS   B HA   1 
ATOM   7758  H  HB2  . LYS   B 1 201 ? 39.923  21.784  49.443  1.00 39.61 ? 200 LYS   B HB2  1 
ATOM   7759  H  HB3  . LYS   B 1 201 ? 38.759  22.031  50.496  1.00 39.61 ? 200 LYS   B HB3  1 
ATOM   7760  H  HG2  . LYS   B 1 201 ? 40.551  19.869  50.711  1.00 46.35 ? 200 LYS   B HG2  1 
ATOM   7761  H  HG3  . LYS   B 1 201 ? 40.763  21.242  51.483  1.00 46.35 ? 200 LYS   B HG3  1 
ATOM   7762  H  HD2  . LYS   B 1 201 ? 38.614  19.481  51.907  1.00 48.75 ? 200 LYS   B HD2  1 
ATOM   7763  H  HD3  . LYS   B 1 201 ? 39.829  19.693  52.909  1.00 48.75 ? 200 LYS   B HD3  1 
ATOM   7764  H  HE2  . LYS   B 1 201 ? 37.752  21.535  52.392  1.00 52.41 ? 200 LYS   B HE2  1 
ATOM   7765  H  HE3  . LYS   B 1 201 ? 38.107  20.882  53.797  1.00 52.41 ? 200 LYS   B HE3  1 
ATOM   7766  H  HZ1  . LYS   B 1 201 ? 38.996  22.816  54.035  1.00 69.75 ? 200 LYS   B HZ1  1 
ATOM   7767  H  HZ2  . LYS   B 1 201 ? 40.150  22.158  53.457  1.00 69.75 ? 200 LYS   B HZ2  1 
ATOM   7768  H  HZ3  . LYS   B 1 201 ? 39.304  22.995  52.631  1.00 69.75 ? 200 LYS   B HZ3  1 
ATOM   7769  N  N    . GLY   B 1 202 ? 36.579  22.042  48.758  1.00 32.09 ? 201 GLY   B N    1 
ATOM   7770  C  CA   . GLY   B 1 202 ? 35.842  23.002  47.953  1.00 31.75 ? 201 GLY   B CA   1 
ATOM   7771  C  C    . GLY   B 1 202 ? 34.995  22.340  46.885  1.00 29.96 ? 201 GLY   B C    1 
ATOM   7772  O  O    . GLY   B 1 202 ? 34.412  21.267  47.084  1.00 26.33 ? 201 GLY   B O    1 
ATOM   7773  H  H    . GLY   B 1 202 ? 36.308  21.972  49.572  1.00 38.51 ? 201 GLY   B H    1 
ATOM   7774  H  HA2  . GLY   B 1 202 ? 35.257  23.520  48.527  1.00 38.10 ? 201 GLY   B HA2  1 
ATOM   7775  H  HA3  . GLY   B 1 202 ? 36.468  23.601  47.516  1.00 38.10 ? 201 GLY   B HA3  1 
ATOM   7776  N  N    . VAL   B 1 203 ? 34.864  22.982  45.721  1.00 26.91 ? 202 VAL   B N    1 
ATOM   7777  C  CA   . VAL   B 1 203 ? 34.052  22.484  44.634  1.00 29.13 ? 202 VAL   B CA   1 
ATOM   7778  C  C    . VAL   B 1 203 ? 34.436  21.108  44.119  1.00 28.04 ? 202 VAL   B C    1 
ATOM   7779  O  O    . VAL   B 1 203 ? 33.630  20.319  43.815  1.00 23.46 ? 202 VAL   B O    1 
ATOM   7780  C  CB   . VAL   B 1 203 ? 34.092  23.419  43.452  1.00 32.16 ? 202 VAL   B CB   1 
ATOM   7781  C  CG1  . VAL   B 1 203 ? 33.221  22.885  42.347  1.00 33.63 ? 202 VAL   B CG1  1 
ATOM   7782  C  CG2  . VAL   B 1 203 ? 33.676  24.782  43.886  1.00 36.20 ? 202 VAL   B CG2  1 
ATOM   7783  H  H    . VAL   B 1 203 ? 35.211  23.739  45.502  1.00 32.29 ? 202 VAL   B H    1 
ATOM   7784  H  HA   . VAL   B 1 203 ? 33.122  22.434  44.941  1.00 34.96 ? 202 VAL   B HA   1 
ATOM   7785  H  HB   . VAL   B 1 203 ? 35.011  23.473  43.117  1.00 38.59 ? 202 VAL   B HB   1 
ATOM   7786  H  HG11 . VAL   B 1 203 ? 33.010  23.600  41.743  1.00 40.35 ? 202 VAL   B HG11 1 
ATOM   7787  H  HG12 . VAL   B 1 203 ? 33.697  22.193  41.883  1.00 40.35 ? 202 VAL   B HG12 1 
ATOM   7788  H  HG13 . VAL   B 1 203 ? 32.416  22.529  42.729  1.00 40.35 ? 202 VAL   B HG13 1 
ATOM   7789  H  HG21 . VAL   B 1 203 ? 33.330  25.259  43.128  1.00 43.44 ? 202 VAL   B HG21 1 
ATOM   7790  H  HG22 . VAL   B 1 203 ? 32.997  24.702  44.560  1.00 43.44 ? 202 VAL   B HG22 1 
ATOM   7791  H  HG23 . VAL   B 1 203 ? 34.439  25.243  44.243  1.00 43.44 ? 202 VAL   B HG23 1 
ATOM   7792  N  N    . GLU   B 1 204 ? 35.729  20.822  44.191  1.00 22.31 ? 203 GLU   B N    1 
ATOM   7793  C  CA   . GLU   B 1 204 ? 36.239  19.523  43.793  1.00 20.86 ? 203 GLU   B CA   1 
ATOM   7794  C  C    . GLU   B 1 204 ? 35.749  18.447  44.771  1.00 23.69 ? 203 GLU   B C    1 
ATOM   7795  O  O    . GLU   B 1 204 ? 35.685  17.271  44.413  1.00 23.48 ? 203 GLU   B O    1 
ATOM   7796  C  CB   . GLU   B 1 204 ? 37.767  19.540  43.743  1.00 26.57 ? 203 GLU   B CB   1 
ATOM   7797  C  CG   . GLU   B 1 204 ? 38.334  20.369  42.601  1.00 41.15 ? 203 GLU   B CG   1 
ATOM   7798  C  CD   . GLU   B 1 204 ? 39.834  20.210  42.451  1.00 60.48 ? 203 GLU   B CD   1 
ATOM   7799  O  OE1  . GLU   B 1 204 ? 40.490  19.789  43.427  1.00 50.10 ? 203 GLU   B OE1  1 
ATOM   7800  O  OE2  . GLU   B 1 204 ? 40.358  20.507  41.357  1.00 64.86 ? 203 GLU   B OE2  1 
ATOM   7801  H  H    . GLU   B 1 204 ? 36.333  21.367  44.470  1.00 26.77 ? 203 GLU   B H    1 
ATOM   7802  H  HA   . GLU   B 1 204 ? 35.904  19.302  42.899  1.00 25.04 ? 203 GLU   B HA   1 
ATOM   7803  H  HB2  . GLU   B 1 204 ? 38.103  19.912  44.573  1.00 31.88 ? 203 GLU   B HB2  1 
ATOM   7804  H  HB3  . GLU   B 1 204 ? 38.087  18.630  43.637  1.00 31.88 ? 203 GLU   B HB3  1 
ATOM   7805  H  HG2  . GLU   B 1 204 ? 37.918  20.090  41.771  1.00 49.38 ? 203 GLU   B HG2  1 
ATOM   7806  H  HG3  . GLU   B 1 204 ? 38.147  21.306  42.768  1.00 49.38 ? 203 GLU   B HG3  1 
ATOM   7807  N  N    . ALA   B 1 205 ? 35.404  18.840  46.000  1.00 18.99 ? 204 ALA   B N    1 
ATOM   7808  C  CA   . ALA   B 1 205 ? 34.920  17.867  46.973  1.00 21.11 ? 204 ALA   B CA   1 
ATOM   7809  C  C    . ALA   B 1 205 ? 33.461  17.474  46.763  1.00 21.56 ? 204 ALA   B C    1 
ATOM   7810  O  O    . ALA   B 1 205 ? 33.028  16.458  47.325  1.00 22.13 ? 204 ALA   B O    1 
ATOM   7811  C  CB   . ALA   B 1 205 ? 35.087  18.410  48.386  1.00 21.21 ? 204 ALA   B CB   1 
ATOM   7812  H  H    . ALA   B 1 205 ? 35.451  19.651  46.282  1.00 22.78 ? 204 ALA   B H    1 
ATOM   7813  H  HA   . ALA   B 1 205 ? 35.459  17.065  46.887  1.00 25.33 ? 204 ALA   B HA   1 
ATOM   7814  H  HB1  . ALA   B 1 205 ? 35.223  17.667  48.996  1.00 25.46 ? 204 ALA   B HB1  1 
ATOM   7815  H  HB2  . ALA   B 1 205 ? 35.856  19.001  48.409  1.00 25.46 ? 204 ALA   B HB2  1 
ATOM   7816  H  HB3  . ALA   B 1 205 ? 34.287  18.899  48.634  1.00 25.46 ? 204 ALA   B HB3  1 
ATOM   7817  N  N    . VAL   B 1 206 ? 32.695  18.212  45.954  1.00 18.41 ? 205 VAL   B N    1 
ATOM   7818  C  CA   . VAL   B 1 206 ? 31.285  17.892  45.772  1.00 16.79 ? 205 VAL   B CA   1 
ATOM   7819  C  C    . VAL   B 1 206 ? 30.949  17.372  44.373  1.00 17.88 ? 205 VAL   B C    1 
ATOM   7820  O  O    . VAL   B 1 206 ? 29.777  17.067  44.119  1.00 22.60 ? 205 VAL   B O    1 
ATOM   7821  C  CB   . VAL   B 1 206 ? 30.361  19.073  46.133  1.00 18.72 ? 205 VAL   B CB   1 
ATOM   7822  C  CG1  . VAL   B 1 206 ? 30.574  19.517  47.612  1.00 19.55 ? 205 VAL   B CG1  1 
ATOM   7823  C  CG2  . VAL   B 1 206 ? 30.538  20.241  45.186  1.00 20.76 ? 205 VAL   B CG2  1 
ATOM   7824  H  H    . VAL   B 1 206 ? 32.971  18.893  45.508  1.00 22.10 ? 205 VAL   B H    1 
ATOM   7825  H  HA   . VAL   B 1 206 ? 31.091  17.172  46.392  1.00 20.15 ? 205 VAL   B HA   1 
ATOM   7826  H  HB   . VAL   B 1 206 ? 29.446  18.768  46.039  1.00 22.46 ? 205 VAL   B HB   1 
ATOM   7827  H  HG11 . VAL   B 1 206 ? 29.755  19.919  47.942  1.00 23.46 ? 205 VAL   B HG11 1 
ATOM   7828  H  HG12 . VAL   B 1 206 ? 30.799  18.739  48.146  1.00 23.46 ? 205 VAL   B HG12 1 
ATOM   7829  H  HG13 . VAL   B 1 206 ? 31.296  20.163  47.647  1.00 23.46 ? 205 VAL   B HG13 1 
ATOM   7830  H  HG21 . VAL   B 1 206 ? 29.784  20.844  45.284  1.00 24.91 ? 205 VAL   B HG21 1 
ATOM   7831  H  HG22 . VAL   B 1 206 ? 31.362  20.704  45.404  1.00 24.91 ? 205 VAL   B HG22 1 
ATOM   7832  H  HG23 . VAL   B 1 206 ? 30.577  19.907  44.276  1.00 24.91 ? 205 VAL   B HG23 1 
ATOM   7833  N  N    . MET   B 1 207 ? 31.925  17.248  43.471  1.00 20.69 ? 206 MET   B N    1 
ATOM   7834  C  CA   . MET   B 1 207 ? 31.691  16.843  42.090  1.00 24.32 ? 206 MET   B CA   1 
ATOM   7835  C  C    . MET   B 1 207 ? 32.472  15.582  41.772  1.00 21.94 ? 206 MET   B C    1 
ATOM   7836  O  O    . MET   B 1 207 ? 33.579  15.384  42.268  1.00 25.40 ? 206 MET   B O    1 
ATOM   7837  C  CB   . MET   B 1 207 ? 32.101  17.988  41.162  1.00 24.81 ? 206 MET   B CB   1 
ATOM   7838  C  CG   . MET   B 1 207 ? 31.079  19.125  41.192  1.00 26.42 ? 206 MET   B CG   1 
ATOM   7839  S  SD   . MET   B 1 207 ? 31.465  20.454  40.032  1.00 31.61 ? 206 MET   B SD   1 
ATOM   7840  C  CE   . MET   B 1 207 ? 30.805  19.848  38.490  1.00 40.33 ? 206 MET   B CE   1 
ATOM   7841  H  H    . MET   B 1 207 ? 32.754  17.398  43.644  1.00 24.83 ? 206 MET   B H    1 
ATOM   7842  H  HA   . MET   B 1 207 ? 30.753  16.641  41.948  1.00 29.19 ? 206 MET   B HA   1 
ATOM   7843  H  HB2  . MET   B 1 207 ? 32.959  18.340  41.446  1.00 29.78 ? 206 MET   B HB2  1 
ATOM   7844  H  HB3  . MET   B 1 207 ? 32.164  17.656  40.253  1.00 29.78 ? 206 MET   B HB3  1 
ATOM   7845  H  HG2  . MET   B 1 207 ? 30.206  18.771  40.961  1.00 31.70 ? 206 MET   B HG2  1 
ATOM   7846  H  HG3  . MET   B 1 207 ? 31.057  19.505  42.085  1.00 31.70 ? 206 MET   B HG3  1 
ATOM   7847  H  HE1  . MET   B 1 207 ? 31.216  20.334  37.758  1.00 48.39 ? 206 MET   B HE1  1 
ATOM   7848  H  HE2  . MET   B 1 207 ? 31.004  18.902  38.412  1.00 48.39 ? 206 MET   B HE2  1 
ATOM   7849  H  HE3  . MET   B 1 207 ? 29.845  19.986  38.482  1.00 48.39 ? 206 MET   B HE3  1 
ATOM   7850  N  N    . TYR   B 1 208 ? 31.873  14.716  40.959  1.00 21.61 ? 207 TYR   B N    1 
ATOM   7851  C  CA   . TYR   B 1 208 ? 32.567  13.538  40.466  1.00 21.14 ? 207 TYR   B CA   1 
ATOM   7852  C  C    . TYR   B 1 208 ? 32.066  13.231  39.070  1.00 23.53 ? 207 TYR   B C    1 
ATOM   7853  O  O    . TYR   B 1 208 ? 30.863  13.337  38.811  1.00 21.16 ? 207 TYR   B O    1 
ATOM   7854  C  CB   . TYR   B 1 208 ? 32.330  12.324  41.353  1.00 25.98 ? 207 TYR   B CB   1 
ATOM   7855  C  CG   . TYR   B 1 208 ? 33.153  11.172  40.895  1.00 24.09 ? 207 TYR   B CG   1 
ATOM   7856  C  CD1  . TYR   B 1 208 ? 34.516  11.151  41.141  1.00 33.20 ? 207 TYR   B CD1  1 
ATOM   7857  C  CD2  . TYR   B 1 208 ? 32.595  10.124  40.163  1.00 25.11 ? 207 TYR   B CD2  1 
ATOM   7858  C  CE1  . TYR   B 1 208 ? 35.307  10.112  40.697  1.00 37.16 ? 207 TYR   B CE1  1 
ATOM   7859  C  CE2  . TYR   B 1 208 ? 33.378  9.066   39.736  1.00 25.89 ? 207 TYR   B CE2  1 
ATOM   7860  C  CZ   . TYR   B 1 208 ? 34.732  9.067   40.005  1.00 33.25 ? 207 TYR   B CZ   1 
ATOM   7861  O  OH   . TYR   B 1 208 ? 35.526  8.033   39.584  1.00 29.40 ? 207 TYR   B OH   1 
ATOM   7862  H  H    . TYR   B 1 208 ? 31.063  14.793  40.678  1.00 25.93 ? 207 TYR   B H    1 
ATOM   7863  H  HA   . TYR   B 1 208 ? 33.520  13.720  40.439  1.00 25.37 ? 207 TYR   B HA   1 
ATOM   7864  H  HB2  . TYR   B 1 208 ? 32.578  12.537  42.267  1.00 31.17 ? 207 TYR   B HB2  1 
ATOM   7865  H  HB3  . TYR   B 1 208 ? 31.395  12.072  41.314  1.00 31.17 ? 207 TYR   B HB3  1 
ATOM   7866  H  HD1  . TYR   B 1 208 ? 34.905  11.850  41.615  1.00 39.83 ? 207 TYR   B HD1  1 
ATOM   7867  H  HD2  . TYR   B 1 208 ? 31.688  10.136  39.961  1.00 30.13 ? 207 TYR   B HD2  1 
ATOM   7868  H  HE1  . TYR   B 1 208 ? 36.222  10.116  40.862  1.00 44.59 ? 207 TYR   B HE1  1 
ATOM   7869  H  HE2  . TYR   B 1 208 ? 32.994  8.358   39.270  1.00 31.07 ? 207 TYR   B HE2  1 
ATOM   7870  H  HH   . TYR   B 1 208 ? 35.188  7.299   39.816  1.00 35.28 ? 207 TYR   B HH   1 
ATOM   7871  N  N    . MET   B 1 209 ? 32.985  12.848  38.182  1.00 22.85 ? 208 MET   B N    1 
ATOM   7872  C  CA   . MET   B 1 209 ? 32.656  12.555  36.791  1.00 25.26 ? 208 MET   B CA   1 
ATOM   7873  C  C    . MET   B 1 209 ? 33.085  11.120  36.521  1.00 21.82 ? 208 MET   B C    1 
ATOM   7874  O  O    . MET   B 1 209 ? 34.273  10.793  36.645  1.00 23.42 ? 208 MET   B O    1 
ATOM   7875  C  CB   . MET   B 1 209 ? 33.398  13.480  35.837  1.00 25.29 ? 208 MET   B CB   1 
ATOM   7876  C  CG   . MET   B 1 209 ? 32.918  13.488  34.361  1.00 30.13 ? 208 MET   B CG   1 
ATOM   7877  S  SD   . MET   B 1 209 ? 31.149  13.365  34.048  1.00 24.46 ? 208 MET   B SD   1 
ATOM   7878  C  CE   . MET   B 1 209 ? 31.094  13.803  32.293  1.00 30.11 ? 208 MET   B CE   1 
ATOM   7879  H  H    . MET   B 1 209 ? 33.819  12.750  38.368  1.00 27.42 ? 208 MET   B H    1 
ATOM   7880  H  HA   . MET   B 1 209 ? 31.703  12.672  36.653  1.00 30.31 ? 208 MET   B HA   1 
ATOM   7881  H  HB2  . MET   B 1 209 ? 33.309  14.387  36.169  1.00 30.35 ? 208 MET   B HB2  1 
ATOM   7882  H  HB3  . MET   B 1 209 ? 34.332  13.219  35.830  1.00 30.35 ? 208 MET   B HB3  1 
ATOM   7883  H  HG2  . MET   B 1 209 ? 33.215  14.319  33.958  1.00 36.15 ? 208 MET   B HG2  1 
ATOM   7884  H  HG3  . MET   B 1 209 ? 33.332  12.734  33.911  1.00 36.15 ? 208 MET   B HG3  1 
ATOM   7885  H  HE1  . MET   B 1 209 ? 30.504  13.185  31.832  1.00 36.14 ? 208 MET   B HE1  1 
ATOM   7886  H  HE2  . MET   B 1 209 ? 30.759  14.709  32.204  1.00 36.14 ? 208 MET   B HE2  1 
ATOM   7887  H  HE3  . MET   B 1 209 ? 31.989  13.743  31.924  1.00 36.14 ? 208 MET   B HE3  1 
ATOM   7888  N  N    . GLY   B 1 210 ? 32.133  10.249  36.205  1.00 22.99 ? 209 GLY   B N    1 
ATOM   7889  C  CA   . GLY   B 1 210 ? 32.467  8.856   35.968  1.00 26.55 ? 209 GLY   B CA   1 
ATOM   7890  C  C    . GLY   B 1 210 ? 31.460  7.820   36.438  1.00 28.45 ? 209 GLY   B C    1 
ATOM   7891  O  O    . GLY   B 1 210 ? 31.380  6.729   35.865  1.00 29.20 ? 209 GLY   B O    1 
ATOM   7892  H  H    . GLY   B 1 210 ? 31.298  10.440  36.123  1.00 27.59 ? 209 GLY   B H    1 
ATOM   7893  H  HA2  . GLY   B 1 210 ? 32.584  8.730   35.014  1.00 31.86 ? 209 GLY   B HA2  1 
ATOM   7894  H  HA3  . GLY   B 1 210 ? 33.305  8.665   36.417  1.00 31.86 ? 209 GLY   B HA3  1 
ATOM   7895  N  N    . THR   B 1 211 ? 30.692  8.142   37.477  1.00 24.33 ? 210 THR   B N    1 
ATOM   7896  C  CA   . THR   B 1 211 ? 29.656  7.259   37.989  1.00 23.59 ? 210 THR   B CA   1 
ATOM   7897  C  C    . THR   B 1 211 ? 28.504  8.113   38.486  1.00 22.09 ? 210 THR   B C    1 
ATOM   7898  O  O    . THR   B 1 211 ? 28.724  9.206   39.024  1.00 21.49 ? 210 THR   B O    1 
ATOM   7899  C  CB   . THR   B 1 211 ? 30.171  6.400   39.145  1.00 30.97 ? 210 THR   B CB   1 
ATOM   7900  O  OG1  . THR   B 1 211 ? 31.384  5.766   38.740  1.00 38.88 ? 210 THR   B OG1  1 
ATOM   7901  C  CG2  . THR   B 1 211 ? 29.109  5.354   39.502  1.00 28.73 ? 210 THR   B CG2  1 
ATOM   7902  H  H    . THR   B 1 211 ? 30.756  8.883   37.910  1.00 29.19 ? 210 THR   B H    1 
ATOM   7903  H  HA   . THR   B 1 211 ? 29.348  6.676   37.277  1.00 28.30 ? 210 THR   B HA   1 
ATOM   7904  H  HB   . THR   B 1 211 ? 30.347  6.936   39.934  1.00 37.17 ? 210 THR   B HB   1 
ATOM   7905  H  HG1  . THR   B 1 211 ? 31.261  5.337   38.028  1.00 46.65 ? 210 THR   B HG1  1 
ATOM   7906  H  HG21 . THR   B 1 211 ? 29.525  4.485   39.618  1.00 34.47 ? 210 THR   B HG21 1 
ATOM   7907  H  HG22 . THR   B 1 211 ? 28.663  5.602   40.328  1.00 34.47 ? 210 THR   B HG22 1 
ATOM   7908  H  HG23 . THR   B 1 211 ? 28.449  5.295   38.794  1.00 34.47 ? 210 THR   B HG23 1 
ATOM   7909  N  N    . LEU   B 1 212 ? 27.287  7.614   38.310  1.00 21.10 ? 211 LEU   B N    1 
ATOM   7910  C  CA   . LEU   B 1 212 ? 26.111  8.297   38.805  1.00 21.45 ? 211 LEU   B CA   1 
ATOM   7911  C  C    . LEU   B 1 212 ? 25.725  7.867   40.211  1.00 16.97 ? 211 LEU   B C    1 
ATOM   7912  O  O    . LEU   B 1 212 ? 24.981  8.582   40.866  1.00 19.95 ? 211 LEU   B O    1 
ATOM   7913  C  CB   . LEU   B 1 212 ? 24.925  8.026   37.893  1.00 23.26 ? 211 LEU   B CB   1 
ATOM   7914  C  CG   . LEU   B 1 212 ? 25.043  8.609   36.489  1.00 20.78 ? 211 LEU   B CG   1 
ATOM   7915  C  CD1  . LEU   B 1 212 ? 23.815  8.094   35.750  1.00 23.76 ? 211 LEU   B CD1  1 
ATOM   7916  C  CD2  . LEU   B 1 212 ? 25.134  10.148  36.438  1.00 21.73 ? 211 LEU   B CD2  1 
ATOM   7917  H  H    . LEU   B 1 212 ? 27.119  6.876   37.903  1.00 25.32 ? 211 LEU   B H    1 
ATOM   7918  H  HA   . LEU   B 1 212 ? 26.293  9.250   38.808  1.00 25.74 ? 211 LEU   B HA   1 
ATOM   7919  H  HB2  . LEU   B 1 212 ? 24.822  7.065   37.802  1.00 27.91 ? 211 LEU   B HB2  1 
ATOM   7920  H  HB3  . LEU   B 1 212 ? 24.132  8.407   38.301  1.00 27.91 ? 211 LEU   B HB3  1 
ATOM   7921  H  HG   . LEU   B 1 212 ? 25.875  8.333   36.074  1.00 24.94 ? 211 LEU   B HG   1 
ATOM   7922  H  HD11 . LEU   B 1 212 ? 23.558  8.741   35.074  1.00 28.52 ? 211 LEU   B HD11 1 
ATOM   7923  H  HD12 . LEU   B 1 212 ? 24.031  7.246   35.331  1.00 28.52 ? 211 LEU   B HD12 1 
ATOM   7924  H  HD13 . LEU   B 1 212 ? 23.091  7.974   36.385  1.00 28.52 ? 211 LEU   B HD13 1 
ATOM   7925  H  HD21 . LEU   B 1 212 ? 25.066  10.438  35.515  1.00 26.08 ? 211 LEU   B HD21 1 
ATOM   7926  H  HD22 . LEU   B 1 212 ? 24.406  10.524  36.957  1.00 26.08 ? 211 LEU   B HD22 1 
ATOM   7927  H  HD23 . LEU   B 1 212 ? 25.985  10.427  36.810  1.00 26.08 ? 211 LEU   B HD23 1 
ATOM   7928  N  N    . SER   B 1 213 ? 26.177  6.700   40.637  1.00 20.24 ? 212 SER   B N    1 
ATOM   7929  C  CA   . SER   B 1 213 ? 25.695  6.066   41.853  1.00 21.93 ? 212 SER   B CA   1 
ATOM   7930  C  C    . SER   B 1 213 ? 26.560  6.453   43.044  1.00 20.80 ? 212 SER   B C    1 
ATOM   7931  O  O    . SER   B 1 213 ? 27.752  6.133   43.083  1.00 22.25 ? 212 SER   B O    1 
ATOM   7932  C  CB   . SER   B 1 213 ? 25.689  4.544   41.717  1.00 25.81 ? 212 SER   B CB   1 
ATOM   7933  O  OG   . SER   B 1 213 ? 25.383  3.957   42.976  1.00 26.27 ? 212 SER   B OG   1 
ATOM   7934  H  H    . SER   B 1 213 ? 26.779  6.242   40.228  1.00 24.29 ? 212 SER   B H    1 
ATOM   7935  H  HA   . SER   B 1 213 ? 24.792  6.383   42.008  1.00 26.31 ? 212 SER   B HA   1 
ATOM   7936  H  HB2  . SER   B 1 213 ? 25.017  4.282   41.068  1.00 30.97 ? 212 SER   B HB2  1 
ATOM   7937  H  HB3  . SER   B 1 213 ? 26.565  4.244   41.427  1.00 30.97 ? 212 SER   B HB3  1 
ATOM   7938  H  HG   . SER   B 1 213 ? 25.484  3.124   42.936  1.00 31.52 ? 212 SER   B HG   1 
ATOM   7939  N  N    . TYR   B 1 214 ? 25.979  7.119   44.043  1.00 20.14 ? 213 TYR   B N    1 
ATOM   7940  C  CA   . TYR   B 1 214 ? 26.697  7.474   45.243  1.00 22.47 ? 213 TYR   B CA   1 
ATOM   7941  C  C    . TYR   B 1 214 ? 27.054  6.186   45.993  1.00 20.91 ? 213 TYR   B C    1 
ATOM   7942  O  O    . TYR   B 1 214 ? 28.106  6.037   46.454  1.00 20.74 ? 213 TYR   B O    1 
ATOM   7943  C  CB   . TYR   B 1 214 ? 25.842  8.380   46.092  1.00 17.54 ? 213 TYR   B CB   1 
ATOM   7944  C  CG   . TYR   B 1 214 ? 26.533  9.149   47.196  1.00 18.98 ? 213 TYR   B CG   1 
ATOM   7945  C  CD1  . TYR   B 1 214 ? 27.869  9.431   47.170  1.00 19.91 ? 213 TYR   B CD1  1 
ATOM   7946  C  CD2  . TYR   B 1 214 ? 25.814  9.576   48.262  1.00 24.01 ? 213 TYR   B CD2  1 
ATOM   7947  C  CE1  . TYR   B 1 214 ? 28.465  10.154  48.183  1.00 24.67 ? 213 TYR   B CE1  1 
ATOM   7948  C  CE2  . TYR   B 1 214 ? 26.378  10.275  49.274  1.00 20.17 ? 213 TYR   B CE2  1 
ATOM   7949  C  CZ   . TYR   B 1 214 ? 27.712  10.579  49.241  1.00 25.19 ? 213 TYR   B CZ   1 
ATOM   7950  O  OH   . TYR   B 1 214 ? 28.264  11.278  50.263  1.00 23.44 ? 213 TYR   B OH   1 
ATOM   7951  H  H    . TYR   B 1 214 ? 25.172  7.416   44.106  1.00 24.17 ? 213 TYR   B H    1 
ATOM   7952  H  HA   . TYR   B 1 214 ? 27.524  7.946   45.009  1.00 26.96 ? 213 TYR   B HA   1 
ATOM   7953  H  HB2  . TYR   B 1 214 ? 25.424  9.033   45.509  1.00 21.05 ? 213 TYR   B HB2  1 
ATOM   7954  H  HB3  . TYR   B 1 214 ? 25.154  7.838   46.510  1.00 21.05 ? 213 TYR   B HB3  1 
ATOM   7955  H  HD1  . TYR   B 1 214 ? 28.380  9.154   46.444  1.00 23.89 ? 213 TYR   B HD1  1 
ATOM   7956  H  HD2  . TYR   B 1 214 ? 24.904  9.389   48.295  1.00 28.81 ? 213 TYR   B HD2  1 
ATOM   7957  H  HE1  . TYR   B 1 214 ? 29.375  10.343  48.151  1.00 29.60 ? 213 TYR   B HE1  1 
ATOM   7958  H  HE2  . TYR   B 1 214 ? 25.855  10.561  49.988  1.00 24.20 ? 213 TYR   B HE2  1 
ATOM   7959  H  HH   . TYR   B 1 214 ? 27.957  12.038  50.281  1.00 28.13 ? 213 TYR   B HH   1 
ATOM   7960  N  N    . GLU   B 1 215 ? 26.159  5.220   46.009  1.00 24.00 ? 214 GLU   B N    1 
ATOM   7961  C  CA   . GLU   B 1 215 ? 26.440  3.956   46.679  1.00 27.38 ? 214 GLU   B CA   1 
ATOM   7962  C  C    . GLU   B 1 215 ? 27.627  3.236   46.060  1.00 25.72 ? 214 GLU   B C    1 
ATOM   7963  O  O    . GLU   B 1 215 ? 28.418  2.696   46.746  1.00 25.55 ? 214 GLU   B O    1 
ATOM   7964  C  CB   . GLU   B 1 215 ? 25.232  3.034   46.664  1.00 29.62 ? 214 GLU   B CB   1 
ATOM   7965  C  CG   . GLU   B 1 215 ? 24.146  3.434   47.611  1.00 38.99 ? 214 GLU   B CG   1 
ATOM   7966  C  CD   . GLU   B 1 215 ? 24.622  3.506   49.047  1.00 46.10 ? 214 GLU   B CD   1 
ATOM   7967  O  OE1  . GLU   B 1 215 ? 25.293  2.580   49.497  1.00 43.33 ? 214 GLU   B OE1  1 
ATOM   7968  O  OE2  . GLU   B 1 215 ? 24.364  4.521   49.706  1.00 52.66 ? 214 GLU   B OE2  1 
ATOM   7969  H  H    . GLU   B 1 215 ? 25.382  5.265   45.641  1.00 28.79 ? 214 GLU   B H    1 
ATOM   7970  H  HA   . GLU   B 1 215 ? 26.661  4.142   47.615  1.00 32.86 ? 214 GLU   B HA   1 
ATOM   7971  H  HB2  . GLU   B 1 215 ? 24.857  3.022   45.770  1.00 35.54 ? 214 GLU   B HB2  1 
ATOM   7972  H  HB3  . GLU   B 1 215 ? 25.521  2.141   46.910  1.00 35.54 ? 214 GLU   B HB3  1 
ATOM   7973  H  HG2  . GLU   B 1 215 ? 23.817  4.311   47.361  1.00 46.79 ? 214 GLU   B HG2  1 
ATOM   7974  H  HG3  . GLU   B 1 215 ? 23.428  2.783   47.565  1.00 46.79 ? 214 GLU   B HG3  1 
ATOM   7975  N  N    . GLN   B 1 216 ? 27.772  3.299   44.748  1.00 26.45 ? 215 GLN   B N    1 
ATOM   7976  C  CA   . GLN   B 1 216 ? 28.849  2.611   44.071  1.00 27.50 ? 215 GLN   B CA   1 
ATOM   7977  C  C    . GLN   B 1 216 ? 30.150  3.303   44.406  1.00 24.33 ? 215 GLN   B C    1 
ATOM   7978  O  O    . GLN   B 1 216 ? 31.141  2.672   44.536  1.00 26.42 ? 215 GLN   B O    1 
ATOM   7979  C  CB   . GLN   B 1 216 ? 28.626  2.589   42.578  1.00 27.14 ? 215 GLN   B CB   1 
ATOM   7980  C  CG   . GLN   B 1 216 ? 29.512  1.658   41.806  1.00 34.36 ? 215 GLN   B CG   1 
ATOM   7981  C  CD   . GLN   B 1 216 ? 29.400  0.221   42.265  1.00 43.80 ? 215 GLN   B CD   1 
ATOM   7982  O  OE1  . GLN   B 1 216 ? 28.355  -0.368  42.204  1.00 50.00 ? 215 GLN   B OE1  1 
ATOM   7983  N  NE2  . GLN   B 1 216 ? 30.475  -0.317  42.769  1.00 41.40 ? 215 GLN   B NE2  1 
ATOM   7984  H  H    . GLN   B 1 216 ? 27.335  3.828   44.252  1.00 31.74 ? 215 GLN   B H    1 
ATOM   7985  H  HA   . GLN   B 1 216 ? 28.897  1.686   44.391  1.00 33.00 ? 215 GLN   B HA   1 
ATOM   7986  H  HB2  . GLN   B 1 216 ? 27.709  2.324   42.409  1.00 32.57 ? 215 GLN   B HB2  1 
ATOM   7987  H  HB3  . GLN   B 1 216 ? 28.773  3.484   42.232  1.00 32.57 ? 215 GLN   B HB3  1 
ATOM   7988  H  HG2  . GLN   B 1 216 ? 29.266  1.693   40.868  1.00 41.24 ? 215 GLN   B HG2  1 
ATOM   7989  H  HG3  . GLN   B 1 216 ? 30.435  1.937   41.917  1.00 41.24 ? 215 GLN   B HG3  1 
ATOM   7990  H  HE21 . GLN   B 1 216 ? 31.201  0.141   42.819  1.00 49.68 ? 215 GLN   B HE21 1 
ATOM   7991  H  HE22 . GLN   B 1 216 ? 30.457  -1.128  43.052  1.00 49.68 ? 215 GLN   B HE22 1 
ATOM   7992  N  N    . PHE   B 1 217 ? 30.119  4.619   44.475  1.00 22.39 ? 216 PHE   B N    1 
ATOM   7993  C  CA   . PHE   B 1 217 ? 31.297  5.383   44.874  1.00 21.50 ? 216 PHE   B CA   1 
ATOM   7994  C  C    . PHE   B 1 217 ? 31.732  4.989   46.285  1.00 21.98 ? 216 PHE   B C    1 
ATOM   7995  O  O    . PHE   B 1 217 ? 32.929  4.882   46.578  1.00 23.52 ? 216 PHE   B O    1 
ATOM   7996  C  CB   . PHE   B 1 217 ? 30.928  6.874   44.792  1.00 23.88 ? 216 PHE   B CB   1 
ATOM   7997  C  CG   . PHE   B 1 217 ? 32.093  7.828   44.722  1.00 27.25 ? 216 PHE   B CG   1 
ATOM   7998  C  CD1  . PHE   B 1 217 ? 33.186  7.589   43.921  1.00 41.05 ? 216 PHE   B CD1  1 
ATOM   7999  C  CD2  . PHE   B 1 217 ? 32.028  9.018   45.397  1.00 24.27 ? 216 PHE   B CD2  1 
ATOM   8000  C  CE1  . PHE   B 1 217 ? 34.226  8.503   43.854  1.00 39.89 ? 216 PHE   B CE1  1 
ATOM   8001  C  CE2  . PHE   B 1 217 ? 33.056  9.937   45.338  1.00 28.52 ? 216 PHE   B CE2  1 
ATOM   8002  C  CZ   . PHE   B 1 217 ? 34.154  9.684   44.562  1.00 36.63 ? 216 PHE   B CZ   1 
ATOM   8003  H  H    . PHE   B 1 217 ? 29.432  5.110   44.311  1.00 26.87 ? 216 PHE   B H    1 
ATOM   8004  H  HA   . PHE   B 1 217 ? 32.048  5.212   44.285  1.00 25.80 ? 216 PHE   B HA   1 
ATOM   8005  H  HB2  . PHE   B 1 217 ? 30.394  7.012   43.995  1.00 28.66 ? 216 PHE   B HB2  1 
ATOM   8006  H  HB3  . PHE   B 1 217 ? 30.413  7.104   45.581  1.00 28.66 ? 216 PHE   B HB3  1 
ATOM   8007  H  HD1  . PHE   B 1 217 ? 33.228  6.807   43.420  1.00 49.26 ? 216 PHE   B HD1  1 
ATOM   8008  H  HD2  . PHE   B 1 217 ? 31.275  9.211   45.906  1.00 29.12 ? 216 PHE   B HD2  1 
ATOM   8009  H  HE1  . PHE   B 1 217 ? 34.973  8.319   43.331  1.00 47.87 ? 216 PHE   B HE1  1 
ATOM   8010  H  HE2  . PHE   B 1 217 ? 33.002  10.728  45.824  1.00 34.22 ? 216 PHE   B HE2  1 
ATOM   8011  H  HZ   . PHE   B 1 217 ? 34.846  10.303  44.512  1.00 43.95 ? 216 PHE   B HZ   1 
ATOM   8012  N  N    . LYS   B 1 218 ? 30.765  4.750   47.164  1.00 22.74 ? 217 LYS   B N    1 
ATOM   8013  C  CA   . LYS   B 1 218 ? 31.096  4.292   48.514  1.00 25.40 ? 217 LYS   B CA   1 
ATOM   8014  C  C    . LYS   B 1 218 ? 31.631  2.861   48.517  1.00 25.67 ? 217 LYS   B C    1 
ATOM   8015  O  O    . LYS   B 1 218 ? 32.555  2.538   49.275  1.00 30.94 ? 217 LYS   B O    1 
ATOM   8016  C  CB   . LYS   B 1 218 ? 29.863  4.391   49.411  1.00 22.88 ? 217 LYS   B CB   1 
ATOM   8017  C  CG   . LYS   B 1 218 ? 29.448  5.793   49.767  1.00 24.39 ? 217 LYS   B CG   1 
ATOM   8018  C  CD   . LYS   B 1 218 ? 28.067  5.772   50.425  1.00 25.42 ? 217 LYS   B CD   1 
ATOM   8019  C  CE   . LYS   B 1 218 ? 27.591  7.172   50.726  1.00 25.33 ? 217 LYS   B CE   1 
ATOM   8020  N  NZ   . LYS   B 1 218 ? 26.275  7.191   51.420  1.00 27.18 ? 217 LYS   B NZ   1 
ATOM   8021  H  H    . LYS   B 1 218 ? 29.924  4.842   47.011  1.00 27.29 ? 217 LYS   B H    1 
ATOM   8022  H  HA   . LYS   B 1 218 ? 31.790  4.869   48.870  1.00 30.47 ? 217 LYS   B HA   1 
ATOM   8023  H  HB2  . LYS   B 1 218 ? 29.116  3.974   48.954  1.00 27.46 ? 217 LYS   B HB2  1 
ATOM   8024  H  HB3  . LYS   B 1 218 ? 30.047  3.923   50.240  1.00 27.46 ? 217 LYS   B HB3  1 
ATOM   8025  H  HG2  . LYS   B 1 218 ? 30.086  6.175   50.391  1.00 29.27 ? 217 LYS   B HG2  1 
ATOM   8026  H  HG3  . LYS   B 1 218 ? 29.404  6.336   48.965  1.00 29.27 ? 217 LYS   B HG3  1 
ATOM   8027  H  HD2  . LYS   B 1 218 ? 27.430  5.353   49.826  1.00 30.51 ? 217 LYS   B HD2  1 
ATOM   8028  H  HD3  . LYS   B 1 218 ? 28.114  5.278   51.258  1.00 30.51 ? 217 LYS   B HD3  1 
ATOM   8029  H  HE2  . LYS   B 1 218 ? 28.239  7.610   51.299  1.00 30.39 ? 217 LYS   B HE2  1 
ATOM   8030  H  HE3  . LYS   B 1 218 ? 27.499  7.661   49.894  1.00 30.39 ? 217 LYS   B HE3  1 
ATOM   8031  H  HZ1  . LYS   B 1 218 ? 25.869  7.972   51.281  1.00 32.61 ? 217 LYS   B HZ1  1 
ATOM   8032  H  HZ2  . LYS   B 1 218 ? 25.757  6.538   51.109  1.00 32.61 ? 217 LYS   B HZ2  1 
ATOM   8033  H  HZ3  . LYS   B 1 218 ? 26.390  7.077   52.295  1.00 32.61 ? 217 LYS   B HZ3  1 
ATOM   8034  N  N    . LYS   B 1 219 ? 31.077  1.986   47.675  1.00 25.29 ? 218 LYS   B N    1 
ATOM   8035  C  CA   . LYS   B 1 219 ? 31.508  0.590   47.686  1.00 27.53 ? 218 LYS   B CA   1 
ATOM   8036  C  C    . LYS   B 1 219 ? 32.823  0.400   46.944  1.00 32.58 ? 218 LYS   B C    1 
ATOM   8037  O  O    . LYS   B 1 219 ? 33.606  -0.493  47.292  1.00 32.10 ? 218 LYS   B O    1 
ATOM   8038  C  CB   . LYS   B 1 219 ? 30.427  -0.293  47.061  1.00 30.61 ? 218 LYS   B CB   1 
ATOM   8039  C  CG   . LYS   B 1 219 ? 29.128  -0.327  47.838  1.00 39.23 ? 218 LYS   B CG   1 
ATOM   8040  C  CD   . LYS   B 1 219 ? 28.064  -1.113  47.052  1.00 45.57 ? 218 LYS   B CD   1 
ATOM   8041  C  CE   . LYS   B 1 219 ? 27.579  -2.340  47.790  1.00 59.78 ? 218 LYS   B CE   1 
ATOM   8042  N  NZ   . LYS   B 1 219 ? 26.696  -1.980  48.938  1.00 66.66 ? 218 LYS   B NZ   1 
ATOM   8043  H  H    . LYS   B 1 219 ? 30.464  2.172   47.102  1.00 30.35 ? 218 LYS   B H    1 
ATOM   8044  H  HA   . LYS   B 1 219 ? 31.636  0.306   48.604  1.00 33.03 ? 218 LYS   B HA   1 
ATOM   8045  H  HB2  . LYS   B 1 219 ? 30.229  0.041   46.172  1.00 36.73 ? 218 LYS   B HB2  1 
ATOM   8046  H  HB3  . LYS   B 1 219 ? 30.761  -1.202  47.007  1.00 36.73 ? 218 LYS   B HB3  1 
ATOM   8047  H  HG2  . LYS   B 1 219 ? 29.270  -0.763  48.692  1.00 47.08 ? 218 LYS   B HG2  1 
ATOM   8048  H  HG3  . LYS   B 1 219 ? 28.806  0.578   47.977  1.00 47.08 ? 218 LYS   B HG3  1 
ATOM   8049  H  HD2  . LYS   B 1 219 ? 27.300  -0.538  46.892  1.00 54.68 ? 218 LYS   B HD2  1 
ATOM   8050  H  HD3  . LYS   B 1 219 ? 28.444  -1.402  46.208  1.00 54.68 ? 218 LYS   B HD3  1 
ATOM   8051  H  HE2  . LYS   B 1 219 ? 27.073  -2.900  47.181  1.00 71.74 ? 218 LYS   B HE2  1 
ATOM   8052  H  HE3  . LYS   B 1 219 ? 28.342  -2.829  48.135  1.00 71.74 ? 218 LYS   B HE3  1 
ATOM   8053  H  HZ1  . LYS   B 1 219 ? 26.565  -2.692  49.456  1.00 79.99 ? 218 LYS   B HZ1  1 
ATOM   8054  H  HZ2  . LYS   B 1 219 ? 27.074  -1.336  49.422  1.00 79.99 ? 218 LYS   B HZ2  1 
ATOM   8055  H  HZ3  . LYS   B 1 219 ? 25.909  -1.692  48.638  1.00 79.99 ? 218 LYS   B HZ3  1 
ATOM   8056  N  N    . GLY   B 1 220 ? 33.088  1.229   45.938  1.00 29.05 ? 219 GLY   B N    1 
ATOM   8057  C  CA   . GLY   B 1 220 ? 34.285  1.097   45.139  1.00 28.53 ? 219 GLY   B CA   1 
ATOM   8058  C  C    . GLY   B 1 220 ? 34.003  1.085   43.654  1.00 30.11 ? 219 GLY   B C    1 
ATOM   8059  O  O    . GLY   B 1 220 ? 33.113  0.358   43.186  1.00 32.72 ? 219 GLY   B O    1 
ATOM   8060  H  H    . GLY   B 1 220 ? 32.580  1.882   45.701  1.00 34.86 ? 219 GLY   B H    1 
ATOM   8061  H  HA2  . GLY   B 1 220 ? 34.879  1.840   45.329  1.00 34.24 ? 219 GLY   B HA2  1 
ATOM   8062  H  HA3  . GLY   B 1 220 ? 34.733  0.268   45.370  1.00 34.24 ? 219 GLY   B HA3  1 
ATOM   8063  N  N    . VAL   B 1 221 ? 34.735  1.917   42.917  1.00 30.95 ? 220 VAL   B N    1 
ATOM   8064  C  CA   . VAL   B 1 221 ? 34.692  1.943   41.464  1.00 32.20 ? 220 VAL   B CA   1 
ATOM   8065  C  C    . VAL   B 1 221 ? 36.076  1.596   40.937  1.00 41.64 ? 220 VAL   B C    1 
ATOM   8066  O  O    . VAL   B 1 221 ? 37.097  2.003   41.506  1.00 30.98 ? 220 VAL   B O    1 
ATOM   8067  C  CB   . VAL   B 1 221 ? 34.218  3.304   40.910  1.00 36.17 ? 220 VAL   B CB   1 
ATOM   8068  C  CG1  . VAL   B 1 221 ? 32.873  3.677   41.499  1.00 35.79 ? 220 VAL   B CG1  1 
ATOM   8069  C  CG2  . VAL   B 1 221 ? 35.247  4.391   41.170  1.00 38.24 ? 220 VAL   B CG2  1 
ATOM   8070  H  H    . VAL   B 1 221 ? 35.280  2.493   43.250  1.00 37.14 ? 220 VAL   B H    1 
ATOM   8071  H  HA   . VAL   B 1 221 ? 34.065  1.270   41.158  1.00 38.65 ? 220 VAL   B HA   1 
ATOM   8072  H  HB   . VAL   B 1 221 ? 34.116  3.227   39.949  1.00 43.41 ? 220 VAL   B HB   1 
ATOM   8073  H  HG11 . VAL   B 1 221 ? 32.395  4.235   40.866  1.00 42.95 ? 220 VAL   B HG11 1 
ATOM   8074  H  HG12 . VAL   B 1 221 ? 32.368  2.867   41.672  1.00 42.95 ? 220 VAL   B HG12 1 
ATOM   8075  H  HG13 . VAL   B 1 221 ? 33.014  4.162   42.327  1.00 42.95 ? 220 VAL   B HG13 1 
ATOM   8076  H  HG21 . VAL   B 1 221 ? 34.805  5.254   41.153  1.00 45.89 ? 220 VAL   B HG21 1 
ATOM   8077  H  HG22 . VAL   B 1 221 ? 35.650  4.242   42.040  1.00 45.89 ? 220 VAL   B HG22 1 
ATOM   8078  H  HG23 . VAL   B 1 221 ? 35.927  4.353   40.480  1.00 45.89 ? 220 VAL   B HG23 1 
ATOM   8079  N  N    . GLN   B 1 222 ? 36.100  0.856   39.830  1.00 42.31 ? 221 GLN   B N    1 
ATOM   8080  C  CA   . GLN   B 1 222 ? 37.353  0.449   39.211  1.00 42.78 ? 221 GLN   B CA   1 
ATOM   8081  C  C    . GLN   B 1 222 ? 37.871  1.564   38.317  1.00 40.77 ? 221 GLN   B C    1 
ATOM   8082  O  O    . GLN   B 1 222 ? 37.102  2.169   37.565  1.00 35.26 ? 221 GLN   B O    1 
ATOM   8083  C  CB   . GLN   B 1 222 ? 37.153  -0.839  38.410  1.00 46.12 ? 221 GLN   B CB   1 
ATOM   8084  C  CG   . GLN   B 1 222 ? 36.593  -1.966  39.240  1.00 41.57 ? 221 GLN   B CG   1 
ATOM   8085  C  CD   . GLN   B 1 222 ? 37.580  -2.440  40.277  1.00 53.34 ? 221 GLN   B CD   1 
ATOM   8086  O  OE1  . GLN   B 1 222 ? 37.279  -2.470  41.470  1.00 55.42 ? 221 GLN   B OE1  1 
ATOM   8087  N  NE2  . GLN   B 1 222 ? 38.783  -2.776  39.835  1.00 55.07 ? 221 GLN   B NE2  1 
ATOM   8088  H  H    . GLN   B 1 222 ? 35.399  0.576   39.418  1.00 50.77 ? 221 GLN   B H    1 
ATOM   8089  H  HA   . GLN   B 1 222 ? 38.018  0.276   39.896  1.00 51.33 ? 221 GLN   B HA   1 
ATOM   8090  H  HB2  . GLN   B 1 222 ? 36.534  -0.666  37.684  1.00 55.34 ? 221 GLN   B HB2  1 
ATOM   8091  H  HB3  . GLN   B 1 222 ? 38.009  -1.125  38.055  1.00 55.34 ? 221 GLN   B HB3  1 
ATOM   8092  H  HG2  . GLN   B 1 222 ? 35.795  -1.661  39.698  1.00 49.89 ? 221 GLN   B HG2  1 
ATOM   8093  H  HG3  . GLN   B 1 222 ? 36.378  -2.714  38.661  1.00 49.89 ? 221 GLN   B HG3  1 
ATOM   8094  H  HE21 . GLN   B 1 222 ? 38.965  -2.718  38.996  1.00 66.08 ? 221 GLN   B HE21 1 
ATOM   8095  H  HE22 . GLN   B 1 222 ? 39.382  -3.053  40.387  1.00 66.08 ? 221 GLN   B HE22 1 
ATOM   8096  N  N    . ILE   B 1 223 ? 39.159  1.875   38.447  1.00 36.63 ? 222 ILE   B N    1 
ATOM   8097  C  CA   . ILE   B 1 223 ? 39.787  2.891   37.607  1.00 39.92 ? 222 ILE   B CA   1 
ATOM   8098  C  C    . ILE   B 1 223 ? 41.124  2.340   37.120  1.00 46.42 ? 222 ILE   B C    1 
ATOM   8099  O  O    . ILE   B 1 223 ? 41.693  1.420   37.728  1.00 48.65 ? 222 ILE   B O    1 
ATOM   8100  C  CB   . ILE   B 1 223 ? 40.014  4.214   38.370  1.00 37.59 ? 222 ILE   B CB   1 
ATOM   8101  C  CG1  . ILE   B 1 223 ? 40.871  3.938   39.604  1.00 40.31 ? 222 ILE   B CG1  1 
ATOM   8102  C  CG2  . ILE   B 1 223 ? 38.675  4.829   38.758  1.00 43.12 ? 222 ILE   B CG2  1 
ATOM   8103  C  CD1  . ILE   B 1 223 ? 41.282  5.180   40.362  1.00 47.84 ? 222 ILE   B CD1  1 
ATOM   8104  H  H    . ILE   B 1 223 ? 39.692  1.511   39.016  1.00 43.96 ? 222 ILE   B H    1 
ATOM   8105  H  HA   . ILE   B 1 223 ? 39.211  3.066   36.846  1.00 47.90 ? 222 ILE   B HA   1 
ATOM   8106  H  HB   . ILE   B 1 223 ? 40.480  4.845   37.799  1.00 45.11 ? 222 ILE   B HB   1 
ATOM   8107  H  HG12 . ILE   B 1 223 ? 40.366  3.375   40.212  1.00 48.37 ? 222 ILE   B HG12 1 
ATOM   8108  H  HG13 . ILE   B 1 223 ? 41.680  3.483   39.324  1.00 48.37 ? 222 ILE   B HG13 1 
ATOM   8109  H  HG21 . ILE   B 1 223 ? 38.789  5.786   38.874  1.00 51.74 ? 222 ILE   B HG21 1 
ATOM   8110  H  HG22 . ILE   B 1 223 ? 38.032  4.656   38.053  1.00 51.74 ? 222 ILE   B HG22 1 
ATOM   8111  H  HG23 . ILE   B 1 223 ? 38.372  4.429   39.588  1.00 51.74 ? 222 ILE   B HG23 1 
ATOM   8112  H  HD11 . ILE   B 1 223 ? 40.486  5.638   40.673  1.00 57.41 ? 222 ILE   B HD11 1 
ATOM   8113  H  HD12 . ILE   B 1 223 ? 41.831  4.920   41.119  1.00 57.41 ? 222 ILE   B HD12 1 
ATOM   8114  H  HD13 . ILE   B 1 223 ? 41.788  5.758   39.770  1.00 57.41 ? 222 ILE   B HD13 1 
ATOM   8115  N  N    . PRO   B 1 224 ? 41.671  2.913   36.047  1.00 50.29 ? 223 PRO   B N    1 
ATOM   8116  C  CA   . PRO   B 1 224 ? 43.018  2.511   35.610  1.00 52.18 ? 223 PRO   B CA   1 
ATOM   8117  C  C    . PRO   B 1 224 ? 44.079  3.119   36.516  1.00 51.82 ? 223 PRO   B C    1 
ATOM   8118  O  O    . PRO   B 1 224 ? 43.993  4.289   36.895  1.00 58.15 ? 223 PRO   B O    1 
ATOM   8119  C  CB   . PRO   B 1 224 ? 43.109  3.066   34.185  1.00 55.13 ? 223 PRO   B CB   1 
ATOM   8120  C  CG   . PRO   B 1 224 ? 42.176  4.244   34.189  1.00 59.55 ? 223 PRO   B CG   1 
ATOM   8121  C  CD   . PRO   B 1 224 ? 41.050  3.889   35.129  1.00 46.87 ? 223 PRO   B CD   1 
ATOM   8122  N  N    . CYS   B 1 225 ? 45.044  2.306   36.926  1.00 56.99 ? 224 CYS   B N    1 
ATOM   8123  C  CA   . CYS   B 1 225 ? 46.217  2.812   37.620  1.00 55.98 ? 224 CYS   B CA   1 
ATOM   8124  C  C    . CYS   B 1 225 ? 47.438  2.739   36.703  1.00 63.21 ? 224 CYS   B C    1 
ATOM   8125  O  O    . CYS   B 1 225 ? 47.589  1.787   35.926  1.00 57.20 ? 224 CYS   B O    1 
ATOM   8126  C  CB   . CYS   B 1 225 ? 46.424  2.033   38.925  1.00 56.34 ? 224 CYS   B CB   1 
ATOM   8127  S  SG   . CYS   B 1 225 ? 48.097  1.819   39.493  1.00 52.51 ? 224 CYS   B SG   1 
ATOM   8128  N  N    . THR   B 1 226 ? 48.326  3.685   36.830  1.00 52.73 ? 225 THR   B N    1 
ATOM   8129  C  CA   . THR   B 1 226 ? 49.508  3.679   36.025  1.00 58.74 ? 225 THR   B CA   1 
ATOM   8130  C  C    . THR   B 1 226 ? 50.375  2.639   36.657  1.00 62.70 ? 225 THR   B C    1 
ATOM   8131  O  O    . THR   B 1 226 ? 51.091  2.957   37.596  1.00 66.25 ? 225 THR   B O    1 
ATOM   8132  C  CB   . THR   B 1 226 ? 50.214  5.010   36.210  1.00 58.92 ? 225 THR   B CB   1 
ATOM   8133  N  N    . LYS   B 1 229 ? 47.235  -2.537  35.932  1.00 70.89 ? 228 LYS   B N    1 
ATOM   8134  C  CA   . LYS   B 1 229 ? 45.998  -3.075  36.456  1.00 70.01 ? 228 LYS   B CA   1 
ATOM   8135  C  C    . LYS   B 1 229 ? 44.947  -2.006  36.751  1.00 64.48 ? 228 LYS   B C    1 
ATOM   8136  O  O    . LYS   B 1 229 ? 45.192  -0.830  36.591  1.00 65.94 ? 228 LYS   B O    1 
ATOM   8137  C  CB   . LYS   B 1 229 ? 46.304  -3.864  37.724  1.00 74.29 ? 228 LYS   B CB   1 
ATOM   8138  H  H    . LYS   B 1 229 ? 47.822  -2.378  36.540  1.00 85.07 ? 228 LYS   B H    1 
ATOM   8139  H  HA   . LYS   B 1 229 ? 45.619  -3.695  35.799  1.00 84.01 ? 228 LYS   B HA   1 
ATOM   8140  N  N    . GLN   B 1 230 ? 43.761  -2.428  37.150  1.00 61.11 ? 229 GLN   B N    1 
ATOM   8141  C  CA   . GLN   B 1 230 ? 42.720  -1.485  37.500  1.00 59.02 ? 229 GLN   B CA   1 
ATOM   8142  C  C    . GLN   B 1 230 ? 42.822  -1.232  38.974  1.00 55.03 ? 229 GLN   B C    1 
ATOM   8143  O  O    . GLN   B 1 230 ? 43.106  -2.182  39.694  1.00 53.74 ? 229 GLN   B O    1 
ATOM   8144  C  CB   . GLN   B 1 230 ? 41.329  -2.073  37.243  1.00 57.44 ? 229 GLN   B CB   1 
ATOM   8145  C  CG   . GLN   B 1 230 ? 40.899  -2.254  35.803  1.00 49.66 ? 229 GLN   B CG   1 
ATOM   8146  C  CD   . GLN   B 1 230 ? 40.797  -0.962  35.039  1.00 59.44 ? 229 GLN   B CD   1 
ATOM   8147  O  OE1  . GLN   B 1 230 ? 41.715  -0.579  34.338  1.00 60.48 ? 229 GLN   B OE1  1 
ATOM   8148  N  NE2  . GLN   B 1 230 ? 39.676  -0.284  35.162  1.00 57.78 ? 229 GLN   B NE2  1 
ATOM   8149  H  H    . GLN   B 1 230 ? 43.520  -3.251  37.216  1.00 73.33 ? 229 GLN   B H    1 
ATOM   8150  H  HA   . GLN   B 1 230 ? 42.826  -0.645  37.007  1.00 70.82 ? 229 GLN   B HA   1 
ATOM   8151  H  HB2  . GLN   B 1 230 ? 41.291  -2.947  37.663  1.00 68.93 ? 229 GLN   B HB2  1 
ATOM   8152  H  HB3  . GLN   B 1 230 ? 40.676  -1.491  37.663  1.00 68.93 ? 229 GLN   B HB3  1 
ATOM   8153  H  HG2  . GLN   B 1 230 ? 41.546  -2.817  35.351  1.00 59.59 ? 229 GLN   B HG2  1 
ATOM   8154  H  HG3  . GLN   B 1 230 ? 40.026  -2.678  35.788  1.00 59.59 ? 229 GLN   B HG3  1 
ATOM   8155  H  HE21 . GLN   B 1 230 ? 39.581  0.467   34.755  1.00 69.34 ? 229 GLN   B HE21 1 
ATOM   8156  H  HE22 . GLN   B 1 230 ? 39.038  -0.592  35.649  1.00 69.34 ? 229 GLN   B HE22 1 
ATOM   8157  N  N    . ALA   B 1 231 ? 42.650  0.006   39.453  1.00 50.83 ? 230 ALA   B N    1 
ATOM   8158  C  CA   . ALA   B 1 231 ? 42.630  0.105   40.903  1.00 45.82 ? 230 ALA   B CA   1 
ATOM   8159  C  C    . ALA   B 1 231 ? 41.187  0.268   41.362  1.00 39.13 ? 230 ALA   B C    1 
ATOM   8160  O  O    . ALA   B 1 231 ? 40.279  0.452   40.553  1.00 39.67 ? 230 ALA   B O    1 
ATOM   8161  C  CB   . ALA   B 1 231 ? 43.505  1.261   41.385  1.00 42.13 ? 230 ALA   B CB   1 
ATOM   8162  H  H    . ALA   B 1 231 ? 42.571  0.738   39.010  1.00 61.00 ? 230 ALA   B H    1 
ATOM   8163  H  HA   . ALA   B 1 231 ? 42.997  -0.700  41.300  1.00 54.99 ? 230 ALA   B HA   1 
ATOM   8164  H  HB1  . ALA   B 1 231 ? 44.131  0.929   42.048  1.00 50.55 ? 230 ALA   B HB1  1 
ATOM   8165  H  HB2  . ALA   B 1 231 ? 43.989  1.628   40.629  1.00 50.55 ? 230 ALA   B HB2  1 
ATOM   8166  H  HB3  . ALA   B 1 231 ? 42.939  1.944   41.778  1.00 50.55 ? 230 ALA   B HB3  1 
ATOM   8167  N  N    . THR   B 1 232 ? 40.974  0.190   42.674  1.00 35.69 ? 231 THR   B N    1 
ATOM   8168  C  CA   . THR   B 1 232 ? 39.656  0.443   43.241  1.00 35.70 ? 231 THR   B CA   1 
ATOM   8169  C  C    . THR   B 1 232 ? 39.727  1.725   44.048  1.00 32.69 ? 231 THR   B C    1 
ATOM   8170  O  O    . THR   B 1 232 ? 40.568  1.852   44.948  1.00 30.74 ? 231 THR   B O    1 
ATOM   8171  C  CB   . THR   B 1 232 ? 39.144  -0.710  44.100  1.00 38.01 ? 231 THR   B CB   1 
ATOM   8172  O  OG1  . THR   B 1 232 ? 39.139  -1.889  43.296  1.00 38.25 ? 231 THR   B OG1  1 
ATOM   8173  C  CG2  . THR   B 1 232 ? 37.713  -0.424  44.611  1.00 35.12 ? 231 THR   B CG2  1 
ATOM   8174  H  H    . THR   B 1 232 ? 41.579  -0.009  43.253  1.00 42.82 ? 231 THR   B H    1 
ATOM   8175  H  HA   . THR   B 1 232 ? 39.021  0.551   42.515  1.00 42.84 ? 231 THR   B HA   1 
ATOM   8176  H  HB   . THR   B 1 232 ? 39.711  -0.831  44.877  1.00 45.61 ? 231 THR   B HB   1 
ATOM   8177  H  HG1  . THR   B 1 232 ? 38.717  -2.502  43.686  1.00 45.90 ? 231 THR   B HG1  1 
ATOM   8178  H  HG21 . THR   B 1 232 ? 37.252  -1.259  44.789  1.00 42.14 ? 231 THR   B HG21 1 
ATOM   8179  H  HG22 . THR   B 1 232 ? 37.751  0.095   45.430  1.00 42.14 ? 231 THR   B HG22 1 
ATOM   8180  H  HG23 . THR   B 1 232 ? 37.216  0.075   43.945  1.00 42.14 ? 231 THR   B HG23 1 
ATOM   8181  N  N    . LYS   B 1 233 ? 38.873  2.673   43.684  1.00 30.75 ? 232 LYS   B N    1 
ATOM   8182  C  CA   . LYS   B 1 233 ? 38.741  3.954   44.355  1.00 30.76 ? 232 LYS   B CA   1 
ATOM   8183  C  C    . LYS   B 1 233 ? 37.436  3.980   45.133  1.00 26.41 ? 232 LYS   B C    1 
ATOM   8184  O  O    . LYS   B 1 233 ? 36.368  3.677   44.577  1.00 26.62 ? 232 LYS   B O    1 
ATOM   8185  C  CB   . LYS   B 1 233 ? 38.760  5.081   43.327  1.00 31.89 ? 232 LYS   B CB   1 
ATOM   8186  C  CG   . LYS   B 1 233 ? 38.388  6.439   43.890  1.00 31.07 ? 232 LYS   B CG   1 
ATOM   8187  C  CD   . LYS   B 1 233 ? 38.325  7.501   42.784  1.00 37.85 ? 232 LYS   B CD   1 
ATOM   8188  C  CE   . LYS   B 1 233 ? 39.690  8.041   42.411  1.00 43.21 ? 232 LYS   B CE   1 
ATOM   8189  N  NZ   . LYS   B 1 233 ? 39.570  9.285   41.588  1.00 45.03 ? 232 LYS   B NZ   1 
ATOM   8190  H  H    . LYS   B 1 233 ? 38.335  2.591   43.019  1.00 36.90 ? 232 LYS   B H    1 
ATOM   8191  H  HA   . LYS   B 1 233 ? 39.469  4.083   44.982  1.00 36.91 ? 232 LYS   B HA   1 
ATOM   8192  H  HB2  . LYS   B 1 233 ? 39.655  5.149   42.960  1.00 38.26 ? 232 LYS   B HB2  1 
ATOM   8193  H  HB3  . LYS   B 1 233 ? 38.128  4.870   42.623  1.00 38.26 ? 232 LYS   B HB3  1 
ATOM   8194  H  HG2  . LYS   B 1 233 ? 37.516  6.384   44.312  1.00 37.28 ? 232 LYS   B HG2  1 
ATOM   8195  H  HG3  . LYS   B 1 233 ? 39.054  6.712   44.540  1.00 37.28 ? 232 LYS   B HG3  1 
ATOM   8196  H  HD2  . LYS   B 1 233 ? 37.931  7.107   41.989  1.00 45.42 ? 232 LYS   B HD2  1 
ATOM   8197  H  HD3  . LYS   B 1 233 ? 37.782  8.245   43.089  1.00 45.42 ? 232 LYS   B HD3  1 
ATOM   8198  H  HE2  . LYS   B 1 233 ? 40.185  8.253   43.218  1.00 51.86 ? 232 LYS   B HE2  1 
ATOM   8199  H  HE3  . LYS   B 1 233 ? 40.170  7.375   41.893  1.00 51.86 ? 232 LYS   B HE3  1 
ATOM   8200  H  HZ1  . LYS   B 1 233 ? 39.658  9.089   40.724  1.00 54.03 ? 232 LYS   B HZ1  1 
ATOM   8201  H  HZ2  . LYS   B 1 233 ? 38.774  9.662   41.719  1.00 54.03 ? 232 LYS   B HZ2  1 
ATOM   8202  H  HZ3  . LYS   B 1 233 ? 40.205  9.865   41.818  1.00 54.03 ? 232 LYS   B HZ3  1 
ATOM   8203  N  N    . TYR   B 1 234 ? 37.499  4.364   46.410  1.00 26.45 ? 233 TYR   B N    1 
ATOM   8204  C  CA   . TYR   B 1 234 ? 36.261  4.464   47.153  1.00 27.53 ? 233 TYR   B CA   1 
ATOM   8205  C  C    . TYR   B 1 234 ? 36.269  5.666   48.084  1.00 22.12 ? 233 TYR   B C    1 
ATOM   8206  O  O    . TYR   B 1 234 ? 37.314  6.193   48.481  1.00 22.06 ? 233 TYR   B O    1 
ATOM   8207  C  CB   . TYR   B 1 234 ? 35.977  3.176   47.944  1.00 29.64 ? 233 TYR   B CB   1 
ATOM   8208  C  CG   . TYR   B 1 234 ? 36.988  2.837   49.018  1.00 26.50 ? 233 TYR   B CG   1 
ATOM   8209  C  CD1  . TYR   B 1 234 ? 38.137  2.085   48.731  1.00 31.00 ? 233 TYR   B CD1  1 
ATOM   8210  C  CD2  . TYR   B 1 234 ? 36.794  3.262   50.330  1.00 28.12 ? 233 TYR   B CD2  1 
ATOM   8211  C  CE1  . TYR   B 1 234 ? 39.057  1.763   49.731  1.00 31.19 ? 233 TYR   B CE1  1 
ATOM   8212  C  CE2  . TYR   B 1 234 ? 37.704  2.951   51.323  1.00 31.25 ? 233 TYR   B CE2  1 
ATOM   8213  C  CZ   . TYR   B 1 234 ? 38.832  2.219   51.025  1.00 33.44 ? 233 TYR   B CZ   1 
ATOM   8214  O  OH   . TYR   B 1 234 ? 39.710  1.947   52.038  1.00 34.27 ? 233 TYR   B OH   1 
ATOM   8215  H  H    . TYR   B 1 234 ? 38.217  4.560   46.840  1.00 31.74 ? 233 TYR   B H    1 
ATOM   8216  H  HA   . TYR   B 1 234 ? 35.541  4.612   46.521  1.00 33.03 ? 233 TYR   B HA   1 
ATOM   8217  H  HB2  . TYR   B 1 234 ? 35.115  3.268   48.379  1.00 35.56 ? 233 TYR   B HB2  1 
ATOM   8218  H  HB3  . TYR   B 1 234 ? 35.957  2.433   47.321  1.00 35.56 ? 233 TYR   B HB3  1 
ATOM   8219  H  HD1  . TYR   B 1 234 ? 38.288  1.797   47.860  1.00 37.20 ? 233 TYR   B HD1  1 
ATOM   8220  H  HD2  . TYR   B 1 234 ? 36.040  3.764   50.542  1.00 33.74 ? 233 TYR   B HD2  1 
ATOM   8221  H  HE1  . TYR   B 1 234 ? 39.809  1.251   49.534  1.00 37.43 ? 233 TYR   B HE1  1 
ATOM   8222  H  HE2  . TYR   B 1 234 ? 37.554  3.236   52.195  1.00 37.49 ? 233 TYR   B HE2  1 
ATOM   8223  H  HH   . TYR   B 1 234 ? 40.110  1.224   51.886  1.00 41.12 ? 233 TYR   B HH   1 
ATOM   8224  N  N    . LEU   B 1 235 ? 35.070  6.073   48.447  1.00 23.59 ? 234 LEU   B N    1 
ATOM   8225  C  CA   . LEU   B 1 235 ? 34.875  7.241   49.292  1.00 21.56 ? 234 LEU   B CA   1 
ATOM   8226  C  C    . LEU   B 1 235 ? 35.086  6.863   50.754  1.00 24.09 ? 234 LEU   B C    1 
ATOM   8227  O  O    . LEU   B 1 235 ? 34.392  5.989   51.287  1.00 26.26 ? 234 LEU   B O    1 
ATOM   8228  C  CB   . LEU   B 1 235 ? 33.477  7.787   49.068  1.00 22.85 ? 234 LEU   B CB   1 
ATOM   8229  C  CG   . LEU   B 1 235 ? 33.081  9.056   49.800  1.00 22.18 ? 234 LEU   B CG   1 
ATOM   8230  C  CD1  . LEU   B 1 235 ? 33.982  10.183  49.406  1.00 21.64 ? 234 LEU   B CD1  1 
ATOM   8231  C  CD2  . LEU   B 1 235 ? 31.604  9.353   49.468  1.00 21.80 ? 234 LEU   B CD2  1 
ATOM   8232  H  H    . LEU   B 1 235 ? 34.337  5.686   48.215  1.00 28.31 ? 234 LEU   B H    1 
ATOM   8233  H  HA   . LEU   B 1 235 ? 35.523  7.928   49.070  1.00 25.87 ? 234 LEU   B HA   1 
ATOM   8234  H  HB2  . LEU   B 1 235 ? 33.381  7.971   48.121  1.00 27.42 ? 234 LEU   B HB2  1 
ATOM   8235  H  HB3  . LEU   B 1 235 ? 32.846  7.102   49.339  1.00 27.42 ? 234 LEU   B HB3  1 
ATOM   8236  H  HG   . LEU   B 1 235 ? 33.171  8.955   50.760  1.00 26.62 ? 234 LEU   B HG   1 
ATOM   8237  H  HD11 . LEU   B 1 235 ? 33.608  11.015  49.734  1.00 25.97 ? 234 LEU   B HD11 1 
ATOM   8238  H  HD12 . LEU   B 1 235 ? 34.858  10.037  49.796  1.00 25.97 ? 234 LEU   B HD12 1 
ATOM   8239  H  HD13 . LEU   B 1 235 ? 34.050  10.209  48.439  1.00 25.97 ? 234 LEU   B HD13 1 
ATOM   8240  H  HD21 . LEU   B 1 235 ? 31.472  10.314  49.450  1.00 26.16 ? 234 LEU   B HD21 1 
ATOM   8241  H  HD22 . LEU   B 1 235 ? 31.393  8.974   48.600  1.00 26.16 ? 234 LEU   B HD22 1 
ATOM   8242  H  HD23 . LEU   B 1 235 ? 31.041  8.954   50.149  1.00 26.16 ? 234 LEU   B HD23 1 
ATOM   8243  N  N    . VAL   B 1 236 ? 36.047  7.517   51.390  1.00 21.63 ? 235 VAL   B N    1 
ATOM   8244  C  CA   . VAL   B 1 236 ? 36.366  7.312   52.812  1.00 21.52 ? 235 VAL   B CA   1 
ATOM   8245  C  C    . VAL   B 1 236 ? 35.541  8.236   53.692  1.00 23.12 ? 235 VAL   B C    1 
ATOM   8246  O  O    . VAL   B 1 236 ? 34.992  7.822   54.723  1.00 23.70 ? 235 VAL   B O    1 
ATOM   8247  C  CB   . VAL   B 1 236 ? 37.878  7.561   53.044  1.00 23.53 ? 235 VAL   B CB   1 
ATOM   8248  C  CG1  . VAL   B 1 236 ? 38.254  7.520   54.545  1.00 26.52 ? 235 VAL   B CG1  1 
ATOM   8249  C  CG2  . VAL   B 1 236 ? 38.721  6.584   52.265  1.00 29.87 ? 235 VAL   B CG2  1 
ATOM   8250  H  H    . VAL   B 1 236 ? 36.550  8.106   51.015  1.00 25.95 ? 235 VAL   B H    1 
ATOM   8251  H  HA   . VAL   B 1 236 ? 36.158  6.394   53.047  1.00 25.82 ? 235 VAL   B HA   1 
ATOM   8252  H  HB   . VAL   B 1 236 ? 38.069  8.455   52.720  1.00 28.24 ? 235 VAL   B HB   1 
ATOM   8253  H  HG11 . VAL   B 1 236 ? 39.197  7.310   54.628  1.00 31.82 ? 235 VAL   B HG11 1 
ATOM   8254  H  HG12 . VAL   B 1 236 ? 38.073  8.388   54.939  1.00 31.82 ? 235 VAL   B HG12 1 
ATOM   8255  H  HG13 . VAL   B 1 236 ? 37.723  6.839   54.986  1.00 31.82 ? 235 VAL   B HG13 1 
ATOM   8256  H  HG21 . VAL   B 1 236 ? 39.654  6.723   52.490  1.00 35.85 ? 235 VAL   B HG21 1 
ATOM   8257  H  HG22 . VAL   B 1 236 ? 38.455  5.681   52.500  1.00 35.85 ? 235 VAL   B HG22 1 
ATOM   8258  H  HG23 . VAL   B 1 236 ? 38.583  6.734   51.317  1.00 35.85 ? 235 VAL   B HG23 1 
ATOM   8259  N  N    . GLN   B 1 237 ? 35.481  9.511   53.317  1.00 22.63 ? 236 GLN   B N    1 
ATOM   8260  C  CA   . GLN   B 1 237 ? 34.796  10.517  54.115  1.00 21.36 ? 236 GLN   B CA   1 
ATOM   8261  C  C    . GLN   B 1 237 ? 34.243  11.600  53.187  1.00 21.78 ? 236 GLN   B C    1 
ATOM   8262  O  O    . GLN   B 1 237 ? 34.916  12.019  52.245  1.00 22.12 ? 236 GLN   B O    1 
ATOM   8263  C  CB   . GLN   B 1 237 ? 35.748  11.140  55.128  1.00 24.34 ? 236 GLN   B CB   1 
ATOM   8264  C  CG   . GLN   B 1 237 ? 35.090  12.068  56.127  1.00 31.79 ? 236 GLN   B CG   1 
ATOM   8265  C  CD   . GLN   B 1 237 ? 36.102  12.781  57.002  1.00 49.13 ? 236 GLN   B CD   1 
ATOM   8266  O  OE1  . GLN   B 1 237 ? 37.318  12.597  56.851  1.00 49.98 ? 236 GLN   B OE1  1 
ATOM   8267  N  NE2  . GLN   B 1 237 ? 35.606  13.553  57.963  1.00 53.06 ? 236 GLN   B NE2  1 
ATOM   8268  H  H    . GLN   B 1 237 ? 35.833  9.820   52.596  1.00 27.15 ? 236 GLN   B H    1 
ATOM   8269  H  HA   . GLN   B 1 237 ? 34.052  10.112  54.588  1.00 25.63 ? 236 GLN   B HA   1 
ATOM   8270  H  HB2  . GLN   B 1 237 ? 36.176  10.428  55.629  1.00 29.21 ? 236 GLN   B HB2  1 
ATOM   8271  H  HB3  . GLN   B 1 237 ? 36.416  11.655  54.648  1.00 29.21 ? 236 GLN   B HB3  1 
ATOM   8272  H  HG2  . GLN   B 1 237 ? 34.578  12.739  55.649  1.00 38.15 ? 236 GLN   B HG2  1 
ATOM   8273  H  HG3  . GLN   B 1 237 ? 34.504  11.551  56.702  1.00 38.15 ? 236 GLN   B HG3  1 
ATOM   8274  H  HE21 . GLN   B 1 237 ? 34.755  13.626  58.060  1.00 63.68 ? 236 GLN   B HE21 1 
ATOM   8275  H  HE22 . GLN   B 1 237 ? 36.136  13.981  58.488  1.00 63.68 ? 236 GLN   B HE22 1 
ATOM   8276  N  N    . GLN   B 1 238 ? 33.029  12.059  53.479  1.00 19.77 ? 237 GLN   B N    1 
ATOM   8277  C  CA   . GLN   B 1 238 ? 32.395  13.155  52.755  1.00 21.63 ? 237 GLN   B CA   1 
ATOM   8278  C  C    . GLN   B 1 238 ? 31.779  14.123  53.758  1.00 23.23 ? 237 GLN   B C    1 
ATOM   8279  O  O    . GLN   B 1 238 ? 30.949  13.718  54.574  1.00 20.61 ? 237 GLN   B O    1 
ATOM   8280  C  CB   . GLN   B 1 238 ? 31.301  12.639  51.829  1.00 20.16 ? 237 GLN   B CB   1 
ATOM   8281  C  CG   . GLN   B 1 238 ? 30.685  13.699  50.953  1.00 21.21 ? 237 GLN   B CG   1 
ATOM   8282  C  CD   . GLN   B 1 238 ? 31.665  14.211  49.884  1.00 20.87 ? 237 GLN   B CD   1 
ATOM   8283  O  OE1  . GLN   B 1 238 ? 32.467  13.451  49.332  1.00 24.80 ? 237 GLN   B OE1  1 
ATOM   8284  N  NE2  . GLN   B 1 238 ? 31.571  15.483  49.571  1.00 20.25 ? 237 GLN   B NE2  1 
ATOM   8285  H  H    . GLN   B 1 238 ? 32.539  11.741  54.110  1.00 23.72 ? 237 GLN   B H    1 
ATOM   8286  H  HA   . GLN   B 1 238 ? 33.071  13.619  52.236  1.00 25.95 ? 237 GLN   B HA   1 
ATOM   8287  H  HB2  . GLN   B 1 238 ? 31.680  11.960  51.248  1.00 24.19 ? 237 GLN   B HB2  1 
ATOM   8288  H  HB3  . GLN   B 1 238 ? 30.592  12.255  52.369  1.00 24.19 ? 237 GLN   B HB3  1 
ATOM   8289  H  HG2  . GLN   B 1 238 ? 29.911  13.328  50.501  1.00 25.46 ? 237 GLN   B HG2  1 
ATOM   8290  H  HG3  . GLN   B 1 238 ? 30.419  14.452  51.504  1.00 25.46 ? 237 GLN   B HG3  1 
ATOM   8291  H  HE21 . GLN   B 1 238 ? 30.984  15.979  49.957  1.00 24.30 ? 237 GLN   B HE21 1 
ATOM   8292  H  HE22 . GLN   B 1 238 ? 32.095  15.819  48.978  1.00 24.30 ? 237 GLN   B HE22 1 
ATOM   8293  N  N    . GLU   B 1 239 ? 32.173  15.392  53.689  1.00 22.31 ? 238 GLU   B N    1 
ATOM   8294  C  CA   . GLU   B 1 239 ? 31.608  16.455  54.525  1.00 20.87 ? 238 GLU   B CA   1 
ATOM   8295  C  C    . GLU   B 1 239 ? 31.158  17.549  53.561  1.00 24.14 ? 238 GLU   B C    1 
ATOM   8296  O  O    . GLU   B 1 239 ? 31.985  18.333  53.085  1.00 22.59 ? 238 GLU   B O    1 
ATOM   8297  C  CB   . GLU   B 1 239 ? 32.632  16.989  55.510  1.00 28.04 ? 238 GLU   B CB   1 
ATOM   8298  C  CG   . GLU   B 1 239 ? 33.400  15.938  56.256  1.00 33.17 ? 238 GLU   B CG   1 
ATOM   8299  C  CD   . GLU   B 1 239 ? 32.591  15.319  57.369  1.00 40.90 ? 238 GLU   B CD   1 
ATOM   8300  O  OE1  . GLU   B 1 239 ? 31.782  16.060  57.965  1.00 44.73 ? 238 GLU   B OE1  1 
ATOM   8301  O  OE2  . GLU   B 1 239 ? 32.790  14.118  57.683  1.00 48.60 ? 238 GLU   B OE2  1 
ATOM   8302  H  H    . GLU   B 1 239 ? 32.783  15.672  53.152  1.00 26.78 ? 238 GLU   B H    1 
ATOM   8303  H  HA   . GLU   B 1 239 ? 30.851  16.122  55.033  1.00 25.04 ? 238 GLU   B HA   1 
ATOM   8304  H  HB2  . GLU   B 1 239 ? 33.275  17.528  55.022  1.00 33.65 ? 238 GLU   B HB2  1 
ATOM   8305  H  HB3  . GLU   B 1 239 ? 32.172  17.534  56.166  1.00 33.65 ? 238 GLU   B HB3  1 
ATOM   8306  H  HG2  . GLU   B 1 239 ? 33.655  15.234  55.640  1.00 39.80 ? 238 GLU   B HG2  1 
ATOM   8307  H  HG3  . GLU   B 1 239 ? 34.192  16.341  56.646  1.00 39.80 ? 238 GLU   B HG3  1 
ATOM   8308  N  N    . SER   B 1 240 ? 29.868  17.566  53.233  1.00 21.10 ? 239 SER   B N    1 
ATOM   8309  C  CA   . SER   B 1 240 ? 29.285  18.570  52.352  1.00 19.74 ? 239 SER   B CA   1 
ATOM   8310  C  C    . SER   B 1 240 ? 27.781  18.475  52.474  1.00 17.12 ? 239 SER   B C    1 
ATOM   8311  O  O    . SER   B 1 240 ? 27.274  17.448  52.903  1.00 17.87 ? 239 SER   B O    1 
ATOM   8312  C  CB   . SER   B 1 240 ? 29.709  18.348  50.886  1.00 18.84 ? 239 SER   B CB   1 
ATOM   8313  O  OG   . SER   B 1 240 ? 29.289  17.054  50.469  1.00 22.38 ? 239 SER   B OG   1 
ATOM   8314  H  H    . SER   B 1 240 ? 29.296  16.990  53.517  1.00 25.32 ? 239 SER   B H    1 
ATOM   8315  H  HA   . SER   B 1 240 ? 29.571  19.456  52.626  1.00 23.68 ? 239 SER   B HA   1 
ATOM   8316  H  HB2  . SER   B 1 240 ? 29.291  19.019  50.324  1.00 22.61 ? 239 SER   B HB2  1 
ATOM   8317  H  HB3  . SER   B 1 240 ? 30.674  18.412  50.816  1.00 22.61 ? 239 SER   B HB3  1 
ATOM   8318  H  HG   . SER   B 1 240 ? 28.506  17.089  50.166  1.00 26.85 ? 239 SER   B HG   1 
ATOM   8319  N  N    . PRO   B 1 241 ? 27.050  19.509  52.038  1.00 18.08 ? 240 PRO   B N    1 
ATOM   8320  C  CA   . PRO   B 1 241 ? 25.581  19.455  52.100  1.00 21.05 ? 240 PRO   B CA   1 
ATOM   8321  C  C    . PRO   B 1 241 ? 24.938  18.684  50.955  1.00 19.35 ? 240 PRO   B C    1 
ATOM   8322  O  O    . PRO   B 1 241 ? 23.737  18.377  51.034  1.00 19.87 ? 240 PRO   B O    1 
ATOM   8323  C  CB   . PRO   B 1 241 ? 25.169  20.945  52.058  1.00 24.73 ? 240 PRO   B CB   1 
ATOM   8324  C  CG   . PRO   B 1 241 ? 26.274  21.626  51.389  1.00 23.94 ? 240 PRO   B CG   1 
ATOM   8325  C  CD   . PRO   B 1 241 ? 27.548  20.857  51.722  1.00 23.46 ? 240 PRO   B CD   1 
ATOM   8326  H  HA   . PRO   B 1 241 ? 25.298  19.071  52.945  1.00 25.26 ? 240 PRO   B HA   1 
ATOM   8327  H  HB2  . PRO   B 1 241 ? 24.345  21.045  51.555  1.00 29.68 ? 240 PRO   B HB2  1 
ATOM   8328  H  HB3  . PRO   B 1 241 ? 25.050  21.280  52.960  1.00 29.68 ? 240 PRO   B HB3  1 
ATOM   8329  H  HG2  . PRO   B 1 241 ? 26.119  21.626  50.432  1.00 28.72 ? 240 PRO   B HG2  1 
ATOM   8330  H  HG3  . PRO   B 1 241 ? 26.334  22.537  51.716  1.00 28.72 ? 240 PRO   B HG3  1 
ATOM   8331  H  HD2  . PRO   B 1 241 ? 28.148  20.835  50.960  1.00 28.15 ? 240 PRO   B HD2  1 
ATOM   8332  H  HD3  . PRO   B 1 241 ? 27.998  21.248  52.487  1.00 28.15 ? 240 PRO   B HD3  1 
ATOM   8333  N  N    . PHE   B 1 242 ? 25.702  18.382  49.910  1.00 21.10 ? 241 PHE   B N    1 
ATOM   8334  C  CA   . PHE   B 1 242 ? 25.227  17.605  48.768  1.00 19.38 ? 241 PHE   B CA   1 
ATOM   8335  C  C    . PHE   B 1 242 ? 26.456  17.052  48.051  1.00 18.58 ? 241 PHE   B C    1 
ATOM   8336  O  O    . PHE   B 1 242 ? 27.599  17.497  48.272  1.00 17.04 ? 241 PHE   B O    1 
ATOM   8337  C  CB   . PHE   B 1 242 ? 24.381  18.449  47.813  1.00 18.22 ? 241 PHE   B CB   1 
ATOM   8338  C  CG   . PHE   B 1 242 ? 25.147  19.540  47.175  1.00 19.75 ? 241 PHE   B CG   1 
ATOM   8339  C  CD1  . PHE   B 1 242 ? 25.230  20.787  47.784  1.00 20.39 ? 241 PHE   B CD1  1 
ATOM   8340  C  CD2  . PHE   B 1 242 ? 25.819  19.331  45.979  1.00 23.05 ? 241 PHE   B CD2  1 
ATOM   8341  C  CE1  . PHE   B 1 242 ? 25.973  21.798  47.213  1.00 23.76 ? 241 PHE   B CE1  1 
ATOM   8342  C  CE2  . PHE   B 1 242 ? 26.590  20.355  45.420  1.00 24.34 ? 241 PHE   B CE2  1 
ATOM   8343  C  CZ   . PHE   B 1 242 ? 26.641  21.594  46.038  1.00 24.11 ? 241 PHE   B CZ   1 
ATOM   8344  H  H    . PHE   B 1 242 ? 26.525  18.622  49.836  1.00 25.32 ? 241 PHE   B H    1 
ATOM   8345  H  HA   . PHE   B 1 242 ? 24.675  16.871  49.083  1.00 23.25 ? 241 PHE   B HA   1 
ATOM   8346  H  HB2  . PHE   B 1 242 ? 24.033  17.878  47.111  1.00 21.86 ? 241 PHE   B HB2  1 
ATOM   8347  H  HB3  . PHE   B 1 242 ? 23.649  18.848  48.309  1.00 21.86 ? 241 PHE   B HB3  1 
ATOM   8348  H  HD1  . PHE   B 1 242 ? 24.780  20.940  48.583  1.00 24.47 ? 241 PHE   B HD1  1 
ATOM   8349  H  HD2  . PHE   B 1 242 ? 25.756  18.509  45.549  1.00 27.67 ? 241 PHE   B HD2  1 
ATOM   8350  H  HE1  . PHE   B 1 242 ? 26.021  22.627  47.632  1.00 28.51 ? 241 PHE   B HE1  1 
ATOM   8351  H  HE2  . PHE   B 1 242 ? 27.067  20.205  44.636  1.00 29.21 ? 241 PHE   B HE2  1 
ATOM   8352  H  HZ   . PHE   B 1 242 ? 27.129  22.286  45.654  1.00 28.93 ? 241 PHE   B HZ   1 
ATOM   8353  N  N    . VAL   B 1 243 ? 26.195  16.156  47.106  1.00 16.87 ? 242 VAL   B N    1 
ATOM   8354  C  CA   . VAL   B 1 243 ? 27.217  15.699  46.172  1.00 19.56 ? 242 VAL   B CA   1 
ATOM   8355  C  C    . VAL   B 1 243 ? 26.574  15.609  44.782  1.00 20.38 ? 242 VAL   B C    1 
ATOM   8356  O  O    . VAL   B 1 243 ? 25.428  15.297  44.673  1.00 19.74 ? 242 VAL   B O    1 
ATOM   8357  C  CB   . VAL   B 1 243 ? 27.898  14.363  46.481  1.00 17.40 ? 242 VAL   B CB   1 
ATOM   8358  C  CG1  . VAL   B 1 243 ? 28.608  14.434  47.802  1.00 17.02 ? 242 VAL   B CG1  1 
ATOM   8359  C  CG2  . VAL   B 1 243 ? 26.922  13.251  46.479  1.00 26.38 ? 242 VAL   B CG2  1 
ATOM   8360  H  H    . VAL   B 1 243 ? 25.425  15.794  46.983  1.00 20.25 ? 242 VAL   B H    1 
ATOM   8361  H  HA   . VAL   B 1 243 ? 27.918  16.384  46.160  1.00 23.47 ? 242 VAL   B HA   1 
ATOM   8362  H  HB   . VAL   B 1 243 ? 28.566  14.179  45.788  1.00 20.89 ? 242 VAL   B HB   1 
ATOM   8363  H  HG11 . VAL   B 1 243 ? 29.185  13.671  47.887  1.00 20.42 ? 242 VAL   B HG11 1 
ATOM   8364  H  HG12 . VAL   B 1 243 ? 29.126  15.241  47.836  1.00 20.42 ? 242 VAL   B HG12 1 
ATOM   8365  H  HG13 . VAL   B 1 243 ? 27.957  14.432  48.507  1.00 20.42 ? 242 VAL   B HG13 1 
ATOM   8366  H  HG21 . VAL   B 1 243 ? 27.382  12.432  46.678  1.00 31.66 ? 242 VAL   B HG21 1 
ATOM   8367  H  HG22 . VAL   B 1 243 ? 26.254  13.422  47.147  1.00 31.66 ? 242 VAL   B HG22 1 
ATOM   8368  H  HG23 . VAL   B 1 243 ? 26.514  13.196  45.613  1.00 31.66 ? 242 VAL   B HG23 1 
ATOM   8369  N  N    . MET   B 1 244 ? 27.344  15.892  43.756  1.00 20.37 ? 243 MET   B N    1 
ATOM   8370  C  CA   . MET   B 1 244 ? 26.847  15.820  42.415  1.00 18.62 ? 243 MET   B CA   1 
ATOM   8371  C  C    . MET   B 1 244 ? 27.618  14.716  41.707  1.00 16.71 ? 243 MET   B C    1 
ATOM   8372  O  O    . MET   B 1 244 ? 28.773  14.853  41.590  1.00 19.10 ? 243 MET   B O    1 
ATOM   8373  C  CB   . MET   B 1 244 ? 27.081  17.142  41.698  1.00 22.44 ? 243 MET   B CB   1 
ATOM   8374  C  CG   . MET   B 1 244 ? 26.656  17.136  40.265  1.00 17.79 ? 243 MET   B CG   1 
ATOM   8375  S  SD   . MET   B 1 244 ? 26.781  18.702  39.372  1.00 24.03 ? 243 MET   B SD   1 
ATOM   8376  C  CE   . MET   B 1 244 ? 26.006  18.108  37.945  1.00 33.48 ? 243 MET   B CE   1 
ATOM   8377  H  H    . MET   B 1 244 ? 28.172  16.121  43.796  1.00 24.44 ? 243 MET   B H    1 
ATOM   8378  H  HA   . MET   B 1 244 ? 25.880  15.668  42.441  1.00 22.35 ? 243 MET   B HA   1 
ATOM   8379  H  HB2  . MET   B 1 244 ? 26.580  17.837  42.152  1.00 26.93 ? 243 MET   B HB2  1 
ATOM   8380  H  HB3  . MET   B 1 244 ? 28.028  17.349  41.725  1.00 26.93 ? 243 MET   B HB3  1 
ATOM   8381  H  HG2  . MET   B 1 244 ? 27.208  16.494  39.792  1.00 21.35 ? 243 MET   B HG2  1 
ATOM   8382  H  HG3  . MET   B 1 244 ? 25.730  16.853  40.223  1.00 21.35 ? 243 MET   B HG3  1 
ATOM   8383  H  HE1  . MET   B 1 244 ? 25.436  17.372  38.183  1.00 40.17 ? 243 MET   B HE1  1 
ATOM   8384  H  HE2  . MET   B 1 244 ? 25.485  18.814  37.556  1.00 40.17 ? 243 MET   B HE2  1 
ATOM   8385  H  HE3  . MET   B 1 244 ? 26.678  17.816  37.325  1.00 40.17 ? 243 MET   B HE3  1 
ATOM   8386  N  N    . MET   B 1 245 ? 26.951  13.632  41.299  1.00 18.45 ? 244 MET   B N    1 
ATOM   8387  C  CA   . MET   B 1 245 ? 27.593  12.545  40.584  1.00 20.49 ? 244 MET   B CA   1 
ATOM   8388  C  C    . MET   B 1 245 ? 27.191  12.634  39.115  1.00 17.08 ? 244 MET   B C    1 
ATOM   8389  O  O    . MET   B 1 245 ? 25.993  12.748  38.800  1.00 18.42 ? 244 MET   B O    1 
ATOM   8390  C  CB   . MET   B 1 245 ? 27.234  11.166  41.168  1.00 16.69 ? 244 MET   B CB   1 
ATOM   8391  C  CG   . MET   B 1 245 ? 27.307  11.107  42.710  1.00 21.38 ? 244 MET   B CG   1 
ATOM   8392  S  SD   . MET   B 1 245 ? 29.032  10.945  43.203  1.00 23.86 ? 244 MET   B SD   1 
ATOM   8393  C  CE   . MET   B 1 245 ? 29.598  9.456   42.358  1.00 24.60 ? 244 MET   B CE   1 
ATOM   8394  H  H    . MET   B 1 245 ? 26.109  13.518  41.430  1.00 22.14 ? 244 MET   B H    1 
ATOM   8395  H  HA   . MET   B 1 245 ? 28.555  12.632  40.669  1.00 24.59 ? 244 MET   B HA   1 
ATOM   8396  H  HB2  . MET   B 1 245 ? 26.327  10.943  40.906  1.00 20.02 ? 244 MET   B HB2  1 
ATOM   8397  H  HB3  . MET   B 1 245 ? 27.853  10.507  40.817  1.00 20.02 ? 244 MET   B HB3  1 
ATOM   8398  H  HG2  . MET   B 1 245 ? 26.944  11.923  43.090  1.00 25.66 ? 244 MET   B HG2  1 
ATOM   8399  H  HG3  . MET   B 1 245 ? 26.811  10.340  43.036  1.00 25.66 ? 244 MET   B HG3  1 
ATOM   8400  H  HE1  . MET   B 1 245 ? 30.253  9.007   42.915  1.00 29.52 ? 244 MET   B HE1  1 
ATOM   8401  H  HE2  . MET   B 1 245 ? 28.839  8.873   42.204  1.00 29.52 ? 244 MET   B HE2  1 
ATOM   8402  H  HE3  . MET   B 1 245 ? 30.000  9.707   41.511  1.00 29.52 ? 244 MET   B HE3  1 
ATOM   8403  N  N    . SER   B 1 246 ? 28.187  12.652  38.225  1.00 18.55 ? 245 SER   B N    1 
ATOM   8404  C  CA   . SER   B 1 246 ? 27.923  12.799  36.802  1.00 18.23 ? 245 SER   B CA   1 
ATOM   8405  C  C    . SER   B 1 246 ? 28.589  11.694  36.005  1.00 19.16 ? 245 SER   B C    1 
ATOM   8406  O  O    . SER   B 1 246 ? 29.578  11.092  36.433  1.00 20.27 ? 245 SER   B O    1 
ATOM   8407  C  CB   . SER   B 1 246 ? 28.409  14.156  36.272  1.00 19.95 ? 245 SER   B CB   1 
ATOM   8408  O  OG   . SER   B 1 246 ? 27.803  15.248  36.972  1.00 21.97 ? 245 SER   B OG   1 
ATOM   8409  H  H    . SER   B 1 246 ? 29.020  12.579  38.426  1.00 22.26 ? 245 SER   B H    1 
ATOM   8410  H  HA   . SER   B 1 246 ? 26.965  12.726  36.670  1.00 21.88 ? 245 SER   B HA   1 
ATOM   8411  H  HB2  . SER   B 1 246 ? 29.371  14.208  36.384  1.00 23.93 ? 245 SER   B HB2  1 
ATOM   8412  H  HB3  . SER   B 1 246 ? 28.180  14.223  35.331  1.00 23.93 ? 245 SER   B HB3  1 
ATOM   8413  H  HG   . SER   B 1 246 ? 26.977  15.115  37.052  1.00 26.36 ? 245 SER   B HG   1 
ATOM   8414  N  N    . ALA   B 1 247 ? 28.075  11.493  34.794  1.00 20.65 ? 246 ALA   B N    1 
ATOM   8415  C  CA   . ALA   B 1 247 ? 28.672  10.564  33.843  1.00 20.04 ? 246 ALA   B CA   1 
ATOM   8416  C  C    . ALA   B 1 247 ? 28.090  10.849  32.470  1.00 17.95 ? 246 ALA   B C    1 
ATOM   8417  O  O    . ALA   B 1 247 ? 27.000  11.404  32.361  1.00 18.93 ? 246 ALA   B O    1 
ATOM   8418  C  CB   . ALA   B 1 247 ? 28.406  9.101   34.240  1.00 20.85 ? 246 ALA   B CB   1 
ATOM   8419  H  H    . ALA   B 1 247 ? 27.371  11.888  34.497  1.00 24.78 ? 246 ALA   B H    1 
ATOM   8420  H  HA   . ALA   B 1 247 ? 29.631  10.706  33.813  1.00 24.05 ? 246 ALA   B HA   1 
ATOM   8421  H  HB1  . ALA   B 1 247 ? 28.317  8.567   33.435  1.00 25.02 ? 246 ALA   B HB1  1 
ATOM   8422  H  HB2  . ALA   B 1 247 ? 29.151  8.777   34.770  1.00 25.02 ? 246 ALA   B HB2  1 
ATOM   8423  H  HB3  . ALA   B 1 247 ? 27.588  9.057   34.758  1.00 25.02 ? 246 ALA   B HB3  1 
ATOM   8424  N  N    . PRO   B 1 248 ? 28.789  10.473  31.405  1.00 21.32 ? 247 PRO   B N    1 
ATOM   8425  C  CA   . PRO   B 1 248 ? 28.185  10.594  30.079  1.00 21.55 ? 247 PRO   B CA   1 
ATOM   8426  C  C    . PRO   B 1 248 ? 26.842  9.895   30.067  1.00 20.53 ? 247 PRO   B C    1 
ATOM   8427  O  O    . PRO   B 1 248 ? 26.693  8.821   30.677  1.00 21.75 ? 247 PRO   B O    1 
ATOM   8428  C  CB   . PRO   B 1 248 ? 29.203  9.908   29.150  1.00 24.12 ? 247 PRO   B CB   1 
ATOM   8429  C  CG   . PRO   B 1 248 ? 30.532  10.028  29.853  1.00 24.67 ? 247 PRO   B CG   1 
ATOM   8430  C  CD   . PRO   B 1 248 ? 30.145  9.887   31.360  1.00 20.73 ? 247 PRO   B CD   1 
ATOM   8431  H  HA   . PRO   B 1 248 ? 28.088  11.519  29.805  1.00 25.86 ? 247 PRO   B HA   1 
ATOM   8432  H  HB2  . PRO   B 1 248 ? 28.960  8.977   29.026  1.00 28.94 ? 247 PRO   B HB2  1 
ATOM   8433  H  HB3  . PRO   B 1 248 ? 29.224  10.362  28.293  1.00 28.94 ? 247 PRO   B HB3  1 
ATOM   8434  H  HG2  . PRO   B 1 248 ? 31.129  9.317   29.572  1.00 29.61 ? 247 PRO   B HG2  1 
ATOM   8435  H  HG3  . PRO   B 1 248 ? 30.936  10.891  29.670  1.00 29.61 ? 247 PRO   B HG3  1 
ATOM   8436  H  HD2  . PRO   B 1 248 ? 30.129  8.955   31.629  1.00 24.88 ? 247 PRO   B HD2  1 
ATOM   8437  H  HD3  . PRO   B 1 248 ? 30.757  10.384  31.925  1.00 24.88 ? 247 PRO   B HD3  1 
ATOM   8438  N  N    . PRO   B 1 249 ? 25.842  10.466  29.390  1.00 19.95 ? 248 PRO   B N    1 
ATOM   8439  C  CA   . PRO   B 1 249 ? 24.477  9.938   29.483  1.00 21.77 ? 248 PRO   B CA   1 
ATOM   8440  C  C    . PRO   B 1 249 ? 24.427  8.436   29.240  1.00 23.53 ? 248 PRO   B C    1 
ATOM   8441  O  O    . PRO   B 1 249 ? 25.098  7.908   28.352  1.00 24.23 ? 248 PRO   B O    1 
ATOM   8442  C  CB   . PRO   B 1 249 ? 23.728  10.711  28.390  1.00 23.29 ? 248 PRO   B CB   1 
ATOM   8443  C  CG   . PRO   B 1 249 ? 24.462  12.049  28.355  1.00 21.04 ? 248 PRO   B CG   1 
ATOM   8444  C  CD   . PRO   B 1 249 ? 25.903  11.695  28.573  1.00 21.17 ? 248 PRO   B CD   1 
ATOM   8445  H  HA   . PRO   B 1 249 ? 24.097  10.135  30.353  1.00 26.12 ? 248 PRO   B HA   1 
ATOM   8446  H  HB2  . PRO   B 1 249 ? 23.794  10.248  27.540  1.00 27.95 ? 248 PRO   B HB2  1 
ATOM   8447  H  HB3  . PRO   B 1 249 ? 22.796  10.825  28.634  1.00 27.95 ? 248 PRO   B HB3  1 
ATOM   8448  H  HG2  . PRO   B 1 249 ? 24.336  12.476  27.493  1.00 25.25 ? 248 PRO   B HG2  1 
ATOM   8449  H  HG3  . PRO   B 1 249 ? 24.135  12.627  29.062  1.00 25.25 ? 248 PRO   B HG3  1 
ATOM   8450  H  HD2  . PRO   B 1 249 ? 26.347  11.524  27.728  1.00 25.40 ? 248 PRO   B HD2  1 
ATOM   8451  H  HD3  . PRO   B 1 249 ? 26.363  12.403  29.051  1.00 25.40 ? 248 PRO   B HD3  1 
ATOM   8452  N  N    . ALA   B 1 250 ? 23.644  7.752   30.061  1.00 21.26 ? 249 ALA   B N    1 
ATOM   8453  C  CA   . ALA   B 1 250 ? 23.460  6.309   29.932  1.00 29.58 ? 249 ALA   B CA   1 
ATOM   8454  C  C    . ALA   B 1 250 ? 22.155  5.903   30.606  1.00 25.94 ? 249 ALA   B C    1 
ATOM   8455  O  O    . ALA   B 1 250 ? 21.672  6.569   31.531  1.00 21.28 ? 249 ALA   B O    1 
ATOM   8456  C  CB   . ALA   B 1 250 ? 24.630  5.519   30.532  1.00 32.39 ? 249 ALA   B CB   1 
ATOM   8457  H  H    . ALA   B 1 250 ? 23.201  8.101   30.710  1.00 25.52 ? 249 ALA   B H    1 
ATOM   8458  H  HA   . ALA   B 1 250 ? 23.398  6.092   28.989  1.00 35.50 ? 249 ALA   B HA   1 
ATOM   8459  H  HB1  . ALA   B 1 250 ? 24.709  4.671   30.067  1.00 38.87 ? 249 ALA   B HB1  1 
ATOM   8460  H  HB2  . ALA   B 1 250 ? 25.445  6.032   30.425  1.00 38.87 ? 249 ALA   B HB2  1 
ATOM   8461  H  HB3  . ALA   B 1 250 ? 24.456  5.364   31.474  1.00 38.87 ? 249 ALA   B HB3  1 
ATOM   8462  N  N    . GLN   B 1 251 ? 21.606  4.782   30.158  1.00 24.01 ? 250 GLN   B N    1 
ATOM   8463  C  CA   . GLN   B 1 251 ? 20.349  4.297   30.712  1.00 22.45 ? 250 GLN   B CA   1 
ATOM   8464  C  C    . GLN   B 1 251 ? 20.546  3.976   32.183  1.00 21.28 ? 250 GLN   B C    1 
ATOM   8465  O  O    . GLN   B 1 251 ? 21.538  3.345   32.550  1.00 23.39 ? 250 GLN   B O    1 
ATOM   8466  C  CB   . GLN   B 1 251 ? 19.881  3.059   29.937  1.00 27.58 ? 250 GLN   B CB   1 
ATOM   8467  C  CG   . GLN   B 1 251 ? 18.392  2.731   30.087  1.00 28.46 ? 250 GLN   B CG   1 
ATOM   8468  C  CD   . GLN   B 1 251 ? 17.456  3.728   29.375  1.00 30.61 ? 250 GLN   B CD   1 
ATOM   8469  O  OE1  . GLN   B 1 251 ? 17.885  4.754   28.843  1.00 32.03 ? 250 GLN   B OE1  1 
ATOM   8470  N  NE2  . GLN   B 1 251 ? 16.173  3.387   29.334  1.00 36.80 ? 250 GLN   B NE2  1 
ATOM   8471  H  H    . GLN   B 1 251 ? 21.938  4.286   29.539  1.00 28.81 ? 250 GLN   B H    1 
ATOM   8472  H  HA   . GLN   B 1 251 ? 19.657  4.971   30.630  1.00 26.93 ? 250 GLN   B HA   1 
ATOM   8473  H  HB2  . GLN   B 1 251 ? 20.054  3.203   28.993  1.00 33.09 ? 250 GLN   B HB2  1 
ATOM   8474  H  HB3  . GLN   B 1 251 ? 20.382  2.291   30.253  1.00 33.09 ? 250 GLN   B HB3  1 
ATOM   8475  H  HG2  . GLN   B 1 251 ? 18.228  1.852   29.712  1.00 34.15 ? 250 GLN   B HG2  1 
ATOM   8476  H  HG3  . GLN   B 1 251 ? 18.166  2.737   31.031  1.00 34.15 ? 250 GLN   B HG3  1 
ATOM   8477  H  HE21 . GLN   B 1 251 ? 15.912  2.650   29.692  1.00 44.16 ? 250 GLN   B HE21 1 
ATOM   8478  H  HE22 . GLN   B 1 251 ? 15.603  3.904   28.949  1.00 44.16 ? 250 GLN   B HE22 1 
ATOM   8479  N  N    . TYR   B 1 252 ? 19.620  4.450   33.016  1.00 23.66 ? 251 TYR   B N    1 
ATOM   8480  C  CA   . TYR   B 1 252 ? 19.781  4.427   34.476  1.00 19.12 ? 251 TYR   B CA   1 
ATOM   8481  C  C    . TYR   B 1 252 ? 18.413  4.276   35.132  1.00 19.99 ? 251 TYR   B C    1 
ATOM   8482  O  O    . TYR   B 1 252 ? 17.425  4.850   34.679  1.00 25.17 ? 251 TYR   B O    1 
ATOM   8483  C  CB   . TYR   B 1 252 ? 20.511  5.698   34.949  1.00 19.69 ? 251 TYR   B CB   1 
ATOM   8484  C  CG   . TYR   B 1 252 ? 21.097  5.579   36.340  1.00 22.08 ? 251 TYR   B CG   1 
ATOM   8485  C  CD1  . TYR   B 1 252 ? 22.327  4.985   36.541  1.00 20.78 ? 251 TYR   B CD1  1 
ATOM   8486  C  CD2  . TYR   B 1 252 ? 20.424  6.082   37.430  1.00 24.94 ? 251 TYR   B CD2  1 
ATOM   8487  C  CE1  . TYR   B 1 252 ? 22.867  4.855   37.781  1.00 27.12 ? 251 TYR   B CE1  1 
ATOM   8488  C  CE2  . TYR   B 1 252 ? 20.957  5.955   38.696  1.00 22.79 ? 251 TYR   B CE2  1 
ATOM   8489  C  CZ   . TYR   B 1 252 ? 22.187  5.367   38.849  1.00 24.99 ? 251 TYR   B CZ   1 
ATOM   8490  O  OH   . TYR   B 1 252 ? 22.734  5.253   40.091  1.00 28.16 ? 251 TYR   B OH   1 
ATOM   8491  H  H    . TYR   B 1 252 ? 18.876  4.796   32.759  1.00 28.39 ? 251 TYR   B H    1 
ATOM   8492  H  HA   . TYR   B 1 252 ? 20.303  3.659   34.755  1.00 22.95 ? 251 TYR   B HA   1 
ATOM   8493  H  HB2  . TYR   B 1 252 ? 21.239  5.886   34.335  1.00 23.63 ? 251 TYR   B HB2  1 
ATOM   8494  H  HB3  . TYR   B 1 252 ? 19.883  6.437   34.954  1.00 23.63 ? 251 TYR   B HB3  1 
ATOM   8495  H  HD1  . TYR   B 1 252 ? 22.799  4.665   35.807  1.00 24.93 ? 251 TYR   B HD1  1 
ATOM   8496  H  HD2  . TYR   B 1 252 ? 19.606  6.508   37.312  1.00 29.93 ? 251 TYR   B HD2  1 
ATOM   8497  H  HE1  . TYR   B 1 252 ? 23.683  4.426   37.900  1.00 32.55 ? 251 TYR   B HE1  1 
ATOM   8498  H  HE2  . TYR   B 1 252 ? 20.489  6.265   39.437  1.00 27.35 ? 251 TYR   B HE2  1 
ATOM   8499  H  HH   . TYR   B 1 252 ? 23.084  4.495   40.182  1.00 33.79 ? 251 TYR   B HH   1 
ATOM   8500  N  N    . GLU   B 1 253 ? 18.367  3.499   36.218  1.00 25.91 ? 252 GLU   B N    1 
ATOM   8501  C  CA   . GLU   B 1 253 ? 17.141  3.291   36.988  1.00 23.89 ? 252 GLU   B CA   1 
ATOM   8502  C  C    . GLU   B 1 253 ? 17.219  4.163   38.239  1.00 20.61 ? 252 GLU   B C    1 
ATOM   8503  O  O    . GLU   B 1 253 ? 18.138  3.992   39.041  1.00 23.93 ? 252 GLU   B O    1 
ATOM   8504  C  CB   . GLU   B 1 253 ? 17.003  1.811   37.369  1.00 28.90 ? 252 GLU   B CB   1 
ATOM   8505  C  CG   . GLU   B 1 253 ? 15.711  1.415   38.050  1.00 35.13 ? 252 GLU   B CG   1 
ATOM   8506  C  CD   . GLU   B 1 253 ? 15.609  -0.109  38.248  1.00 47.13 ? 252 GLU   B CD   1 
ATOM   8507  O  OE1  . GLU   B 1 253 ? 16.648  -0.795  38.416  1.00 47.47 ? 252 GLU   B OE1  1 
ATOM   8508  O  OE2  . GLU   B 1 253 ? 14.489  -0.633  38.143  1.00 54.35 ? 252 GLU   B OE2  1 
ATOM   8509  H  H    . GLU   B 1 253 ? 19.046  3.076   36.533  1.00 31.09 ? 252 GLU   B H    1 
ATOM   8510  H  HA   . GLU   B 1 253 ? 16.363  3.550   36.470  1.00 28.66 ? 252 GLU   B HA   1 
ATOM   8511  H  HB2  . GLU   B 1 253 ? 17.074  1.282   36.559  1.00 34.68 ? 252 GLU   B HB2  1 
ATOM   8512  H  HB3  . GLU   B 1 253 ? 17.726  1.586   37.976  1.00 34.68 ? 252 GLU   B HB3  1 
ATOM   8513  H  HG2  . GLU   B 1 253 ? 15.666  1.838   38.921  1.00 42.16 ? 252 GLU   B HG2  1 
ATOM   8514  H  HG3  . GLU   B 1 253 ? 14.962  1.701   37.503  1.00 42.16 ? 252 GLU   B HG3  1 
ATOM   8515  N  N    . LEU   B 1 254 ? 16.272  5.079   38.387  1.00 23.29 ? 253 LEU   B N    1 
ATOM   8516  C  CA   . LEU   B 1 254 ? 16.189  5.932   39.587  1.00 24.17 ? 253 LEU   B CA   1 
ATOM   8517  C  C    . LEU   B 1 254 ? 15.073  5.434   40.499  1.00 27.80 ? 253 LEU   B C    1 
ATOM   8518  O  O    . LEU   B 1 254 ? 13.944  5.213   40.051  1.00 26.73 ? 253 LEU   B O    1 
ATOM   8519  C  CB   . LEU   B 1 254 ? 15.914  7.372   39.189  1.00 21.94 ? 253 LEU   B CB   1 
ATOM   8520  C  CG   . LEU   B 1 254 ? 17.063  8.137   38.500  1.00 23.38 ? 253 LEU   B CG   1 
ATOM   8521  C  CD1  . LEU   B 1 254 ? 16.533  9.448   37.922  1.00 26.89 ? 253 LEU   B CD1  1 
ATOM   8522  C  CD2  . LEU   B 1 254 ? 18.233  8.414   39.416  1.00 24.18 ? 253 LEU   B CD2  1 
ATOM   8523  H  H    . LEU   B 1 254 ? 15.657  5.234   37.807  1.00 27.95 ? 253 LEU   B H    1 
ATOM   8524  H  HA   . LEU   B 1 254 ? 17.027  5.889   40.074  1.00 29.00 ? 253 LEU   B HA   1 
ATOM   8525  H  HB2  . LEU   B 1 254 ? 15.163  7.374   38.575  1.00 26.33 ? 253 LEU   B HB2  1 
ATOM   8526  H  HB3  . LEU   B 1 254 ? 15.686  7.866   39.992  1.00 26.33 ? 253 LEU   B HB3  1 
ATOM   8527  H  HG   . LEU   B 1 254 ? 17.402  7.570   37.790  1.00 28.05 ? 253 LEU   B HG   1 
ATOM   8528  H  HD11 . LEU   B 1 254 ? 17.248  9.893   37.440  1.00 32.27 ? 253 LEU   B HD11 1 
ATOM   8529  H  HD12 . LEU   B 1 254 ? 15.799  9.254   37.319  1.00 32.27 ? 253 LEU   B HD12 1 
ATOM   8530  H  HD13 . LEU   B 1 254 ? 16.224  10.012  38.649  1.00 32.27 ? 253 LEU   B HD13 1 
ATOM   8531  H  HD21 . LEU   B 1 254 ? 18.861  8.995   38.958  1.00 29.01 ? 253 LEU   B HD21 1 
ATOM   8532  H  HD22 . LEU   B 1 254 ? 17.909  8.847   40.221  1.00 29.01 ? 253 LEU   B HD22 1 
ATOM   8533  H  HD23 . LEU   B 1 254 ? 18.663  7.575   39.642  1.00 29.01 ? 253 LEU   B HD23 1 
ATOM   8534  N  N    . LYS   B 1 255 ? 15.366  5.283   41.786  1.00 25.52 ? 254 LYS   B N    1 
ATOM   8535  C  CA   . LYS   B 1 255 ? 14.409  4.714   42.715  1.00 27.05 ? 254 LYS   B CA   1 
ATOM   8536  C  C    . LYS   B 1 255 ? 14.022  5.753   43.761  1.00 25.58 ? 254 LYS   B C    1 
ATOM   8537  O  O    . LYS   B 1 255 ? 14.887  6.450   44.296  1.00 22.56 ? 254 LYS   B O    1 
ATOM   8538  C  CB   . LYS   B 1 255 ? 15.013  3.465   43.356  1.00 32.69 ? 254 LYS   B CB   1 
ATOM   8539  C  CG   . LYS   B 1 255 ? 15.123  2.304   42.352  1.00 39.90 ? 254 LYS   B CG   1 
ATOM   8540  C  CD   . LYS   B 1 255 ? 14.370  1.061   42.771  1.00 55.25 ? 254 LYS   B CD   1 
ATOM   8541  C  CE   . LYS   B 1 255 ? 14.157  0.109   41.587  1.00 60.80 ? 254 LYS   B CE   1 
ATOM   8542  N  NZ   . LYS   B 1 255 ? 12.750  -0.415  41.625  1.00 60.93 ? 254 LYS   B NZ   1 
ATOM   8543  H  H    . LYS   B 1 255 ? 16.116  5.506   42.142  1.00 30.63 ? 254 LYS   B H    1 
ATOM   8544  H  HA   . LYS   B 1 255 ? 13.588  4.460   42.265  1.00 32.46 ? 254 LYS   B HA   1 
ATOM   8545  H  HB2  . LYS   B 1 255 ? 15.903  3.672   43.681  1.00 39.22 ? 254 LYS   B HB2  1 
ATOM   8546  H  HB3  . LYS   B 1 255 ? 14.449  3.179   44.092  1.00 39.22 ? 254 LYS   B HB3  1 
ATOM   8547  H  HG2  . LYS   B 1 255 ? 14.762  2.594   41.499  1.00 47.88 ? 254 LYS   B HG2  1 
ATOM   8548  H  HG3  . LYS   B 1 255 ? 16.057  2.064   42.253  1.00 47.88 ? 254 LYS   B HG3  1 
ATOM   8549  H  HD2  . LYS   B 1 255 ? 14.878  0.593   43.452  1.00 66.30 ? 254 LYS   B HD2  1 
ATOM   8550  H  HD3  . LYS   B 1 255 ? 13.501  1.314   43.120  1.00 66.30 ? 254 LYS   B HD3  1 
ATOM   8551  H  HE2  . LYS   B 1 255 ? 14.294  0.585   40.752  1.00 72.96 ? 254 LYS   B HE2  1 
ATOM   8552  H  HE3  . LYS   B 1 255 ? 14.774  -0.637  41.648  1.00 72.96 ? 254 LYS   B HE3  1 
ATOM   8553  H  HZ1  . LYS   B 1 255 ? 12.193  0.181   41.268  1.00 73.11 ? 254 LYS   B HZ1  1 
ATOM   8554  H  HZ2  . LYS   B 1 255 ? 12.506  -0.570  42.467  1.00 73.11 ? 254 LYS   B HZ2  1 
ATOM   8555  H  HZ3  . LYS   B 1 255 ? 12.695  -1.174  41.164  1.00 73.11 ? 254 LYS   B HZ3  1 
ATOM   8556  N  N    . HIS   B 1 256 ? 12.716  5.841   44.035  1.00 22.40 ? 255 HIS   B N    1 
ATOM   8557  C  CA   . HIS   B 1 256 ? 12.165  6.775   45.005  1.00 28.45 ? 255 HIS   B CA   1 
ATOM   8558  C  C    . HIS   B 1 256 ? 12.879  6.674   46.346  1.00 23.81 ? 255 HIS   B C    1 
ATOM   8559  O  O    . HIS   B 1 256 ? 13.074  5.589   46.894  1.00 26.95 ? 255 HIS   B O    1 
ATOM   8560  C  CB   . HIS   B 1 256 ? 10.649  6.532   45.153  1.00 27.25 ? 255 HIS   B CB   1 
ATOM   8561  C  CG   . HIS   B 1 256 ? 9.986   7.345   46.231  1.00 27.54 ? 255 HIS   B CG   1 
ATOM   8562  N  ND1  . HIS   B 1 256 ? 9.648   6.834   47.465  1.00 32.17 ? 255 HIS   B ND1  1 
ATOM   8563  C  CD2  . HIS   B 1 256 ? 9.737   8.677   46.302  1.00 25.29 ? 255 HIS   B CD2  1 
ATOM   8564  C  CE1  . HIS   B 1 256 ? 9.136   7.797   48.213  1.00 29.43 ? 255 HIS   B CE1  1 
ATOM   8565  N  NE2  . HIS   B 1 256 ? 9.188   8.929   47.534  1.00 31.87 ? 255 HIS   B NE2  1 
ATOM   8566  H  H    . HIS   B 1 256 ? 12.115  5.355   43.658  1.00 26.88 ? 255 HIS   B H    1 
ATOM   8567  H  HA   . HIS   B 1 256 ? 12.293  7.682   44.688  1.00 34.14 ? 255 HIS   B HA   1 
ATOM   8568  H  HB2  . HIS   B 1 256 ? 10.218  6.753   44.313  1.00 32.70 ? 255 HIS   B HB2  1 
ATOM   8569  H  HB3  . HIS   B 1 256 ? 10.506  5.596   45.363  1.00 32.70 ? 255 HIS   B HB3  1 
ATOM   8570  H  HD2  . HIS   B 1 256 ? 9.908   9.304   45.637  1.00 30.35 ? 255 HIS   B HD2  1 
ATOM   8571  H  HE1  . HIS   B 1 256 ? 8.796   7.695   49.073  1.00 35.32 ? 255 HIS   B HE1  1 
ATOM   8572  H  HE2  . HIS   B 1 256 ? 8.921   9.697   47.817  1.00 38.25 ? 255 HIS   B HE2  1 
ATOM   8573  N  N    . GLY   B 1 257 ? 13.273  7.836   46.845  1.00 23.68 ? 256 GLY   B N    1 
ATOM   8574  C  CA   . GLY   B 1 257 ? 13.924  7.979   48.134  1.00 22.82 ? 256 GLY   B CA   1 
ATOM   8575  C  C    . GLY   B 1 257 ? 15.399  7.689   48.169  1.00 27.35 ? 256 GLY   B C    1 
ATOM   8576  O  O    . GLY   B 1 257 ? 15.981  7.745   49.256  1.00 25.18 ? 256 GLY   B O    1 
ATOM   8577  H  H    . GLY   B 1 257 ? 13.169  8.587   46.439  1.00 28.42 ? 256 GLY   B H    1 
ATOM   8578  H  HA2  . GLY   B 1 257 ? 13.800  8.892   48.438  1.00 27.39 ? 256 GLY   B HA2  1 
ATOM   8579  H  HA3  . GLY   B 1 257 ? 13.495  7.376   48.761  1.00 27.39 ? 256 GLY   B HA3  1 
ATOM   8580  N  N    . THR   B 1 258 ? 16.050  7.427   47.026  1.00 18.72 ? 257 THR   B N    1 
ATOM   8581  C  CA   . THR   B 1 258 ? 17.461  7.087   47.029  1.00 18.96 ? 257 THR   B CA   1 
ATOM   8582  C  C    . THR   B 1 258 ? 18.337  8.195   46.438  1.00 19.73 ? 257 THR   B C    1 
ATOM   8583  O  O    . THR   B 1 258 ? 19.558  8.030   46.350  1.00 22.49 ? 257 THR   B O    1 
ATOM   8584  C  CB   . THR   B 1 258 ? 17.683  5.775   46.258  1.00 25.65 ? 257 THR   B CB   1 
ATOM   8585  O  OG1  . THR   B 1 258 ? 17.547  6.012   44.853  1.00 23.29 ? 257 THR   B OG1  1 
ATOM   8586  C  CG2  . THR   B 1 258 ? 16.677  4.693   46.639  1.00 27.90 ? 257 THR   B CG2  1 
ATOM   8587  H  H    . THR   B 1 258 ? 15.688  7.443   46.246  1.00 22.46 ? 257 THR   B H    1 
ATOM   8588  H  HA   . THR   B 1 258 ? 17.750  6.943   47.944  1.00 22.75 ? 257 THR   B HA   1 
ATOM   8589  H  HB   . THR   B 1 258 ? 18.572  5.456   46.479  1.00 30.78 ? 257 THR   B HB   1 
ATOM   8590  H  HG1  . THR   B 1 258 ? 16.991  5.475   44.524  1.00 27.95 ? 257 THR   B HG1  1 
ATOM   8591  H  HG21 . THR   B 1 258 ? 16.955  3.838   46.274  1.00 33.48 ? 257 THR   B HG21 1 
ATOM   8592  H  HG22 . THR   B 1 258 ? 16.618  4.619   47.604  1.00 33.48 ? 257 THR   B HG22 1 
ATOM   8593  H  HG23 . THR   B 1 258 ? 15.801  4.916   46.287  1.00 33.48 ? 257 THR   B HG23 1 
ATOM   8594  N  N    . PHE   B 1 259 ? 17.744  9.325   46.083  1.00 20.81 ? 258 PHE   B N    1 
ATOM   8595  C  CA   . PHE   B 1 259 ? 18.439  10.458  45.495  1.00 22.36 ? 258 PHE   B CA   1 
ATOM   8596  C  C    . PHE   B 1 259 ? 17.536  11.666  45.711  1.00 22.72 ? 258 PHE   B C    1 
ATOM   8597  O  O    . PHE   B 1 259 ? 16.357  11.539  46.075  1.00 21.76 ? 258 PHE   B O    1 
ATOM   8598  C  CB   . PHE   B 1 259 ? 18.763  10.196  43.995  1.00 18.77 ? 258 PHE   B CB   1 
ATOM   8599  C  CG   . PHE   B 1 259 ? 17.576  10.277  43.132  1.00 18.37 ? 258 PHE   B CG   1 
ATOM   8600  C  CD1  . PHE   B 1 259 ? 16.657  9.257   43.118  1.00 19.10 ? 258 PHE   B CD1  1 
ATOM   8601  C  CD2  . PHE   B 1 259 ? 17.359  11.402  42.336  1.00 17.65 ? 258 PHE   B CD2  1 
ATOM   8602  C  CE1  . PHE   B 1 259 ? 15.498  9.343   42.346  1.00 18.52 ? 258 PHE   B CE1  1 
ATOM   8603  C  CE2  . PHE   B 1 259 ? 16.195  11.510  41.549  1.00 22.29 ? 258 PHE   B CE2  1 
ATOM   8604  C  CZ   . PHE   B 1 259 ? 15.279  10.475  41.539  1.00 19.38 ? 258 PHE   B CZ   1 
ATOM   8605  H  H    . PHE   B 1 259 ? 16.901  9.466   46.177  1.00 24.98 ? 258 PHE   B H    1 
ATOM   8606  H  HA   . PHE   B 1 259 ? 19.288  10.628  45.933  1.00 26.84 ? 258 PHE   B HA   1 
ATOM   8607  H  HB2  . PHE   B 1 259 ? 19.401  10.860  43.689  1.00 22.52 ? 258 PHE   B HB2  1 
ATOM   8608  H  HB3  . PHE   B 1 259 ? 19.139  9.307   43.904  1.00 22.52 ? 258 PHE   B HB3  1 
ATOM   8609  H  HD1  . PHE   B 1 259 ? 16.809  8.496   43.631  1.00 22.91 ? 258 PHE   B HD1  1 
ATOM   8610  H  HD2  . PHE   B 1 259 ? 17.988  12.087  42.325  1.00 21.18 ? 258 PHE   B HD2  1 
ATOM   8611  H  HE1  . PHE   B 1 259 ? 14.873  8.655   42.364  1.00 22.22 ? 258 PHE   B HE1  1 
ATOM   8612  H  HE2  . PHE   B 1 259 ? 16.044  12.272  41.038  1.00 26.75 ? 258 PHE   B HE2  1 
ATOM   8613  H  HZ   . PHE   B 1 259 ? 14.522  10.527  41.002  1.00 23.25 ? 258 PHE   B HZ   1 
ATOM   8614  N  N    . THR   B 1 260 ? 18.097  12.850  45.492  1.00 18.37 ? 259 THR   B N    1 
ATOM   8615  C  CA   . THR   B 1 260 ? 17.319  14.075  45.550  1.00 17.85 ? 259 THR   B CA   1 
ATOM   8616  C  C    . THR   B 1 260 ? 16.760  14.468  44.186  1.00 20.00 ? 259 THR   B C    1 
ATOM   8617  O  O    . THR   B 1 260 ? 15.540  14.615  44.018  1.00 19.33 ? 259 THR   B O    1 
ATOM   8618  C  CB   . THR   B 1 260 ? 18.190  15.198  46.125  1.00 26.03 ? 259 THR   B CB   1 
ATOM   8619  O  OG1  . THR   B 1 260 ? 18.636  14.807  47.436  1.00 25.50 ? 259 THR   B OG1  1 
ATOM   8620  C  CG2  . THR   B 1 260 ? 17.432  16.521  46.219  1.00 23.58 ? 259 THR   B CG2  1 
ATOM   8621  H  H    . THR   B 1 260 ? 18.929  12.967  45.308  1.00 22.04 ? 259 THR   B H    1 
ATOM   8622  H  HA   . THR   B 1 260 ? 16.561  13.936  46.139  1.00 21.42 ? 259 THR   B HA   1 
ATOM   8623  H  HB   . THR   B 1 260 ? 18.947  15.347  45.537  1.00 31.24 ? 259 THR   B HB   1 
ATOM   8624  H  HG1  . THR   B 1 260 ? 18.003  14.456  47.862  1.00 30.60 ? 259 THR   B HG1  1 
ATOM   8625  H  HG21 . THR   B 1 260 ? 17.829  17.083  46.903  1.00 28.30 ? 259 THR   B HG21 1 
ATOM   8626  H  HG22 . THR   B 1 260 ? 17.470  16.986  45.368  1.00 28.30 ? 259 THR   B HG22 1 
ATOM   8627  H  HG23 . THR   B 1 260 ? 16.504  16.357  46.446  1.00 28.30 ? 259 THR   B HG23 1 
ATOM   8628  N  N    . CYS   B 1 261 ? 17.631  14.663  43.213  1.00 18.28 ? 260 CYS   B N    1 
ATOM   8629  C  CA   . CYS   B 1 261 ? 17.131  15.003  41.879  1.00 18.33 ? 260 CYS   B CA   1 
ATOM   8630  C  C    . CYS   B 1 261 ? 18.190  14.607  40.869  1.00 17.74 ? 260 CYS   B C    1 
ATOM   8631  O  O    . CYS   B 1 261 ? 19.311  14.212  41.226  1.00 19.08 ? 260 CYS   B O    1 
ATOM   8632  C  CB   . CYS   B 1 261 ? 16.765  16.489  41.801  1.00 17.38 ? 260 CYS   B CB   1 
ATOM   8633  S  SG   . CYS   B 1 261 ? 18.113  17.613  42.135  1.00 21.12 ? 260 CYS   B SG   1 
ATOM   8634  H  H    . CYS   B 1 261 ? 18.486  14.607  43.290  1.00 21.93 ? 260 CYS   B H    1 
ATOM   8635  H  HA   . CYS   B 1 261 ? 16.331  14.495  41.672  1.00 22.00 ? 260 CYS   B HA   1 
ATOM   8636  H  HB2  . CYS   B 1 261 ? 16.441  16.680  40.907  1.00 20.86 ? 260 CYS   B HB2  1 
ATOM   8637  H  HB3  . CYS   B 1 261 ? 16.068  16.668  42.452  1.00 20.86 ? 260 CYS   B HB3  1 
ATOM   8638  H  HG   . CYS   B 1 261 ? 17.674  18.722  42.264  1.00 25.34 ? 260 CYS   B HG   1 
ATOM   8639  N  N    . ALA   B 1 262 ? 17.816  14.692  39.580  1.00 19.48 ? 261 ALA   B N    1 
ATOM   8640  C  CA   . ALA   B 1 262 ? 18.684  14.154  38.554  1.00 17.85 ? 261 ALA   B CA   1 
ATOM   8641  C  C    . ALA   B 1 262 ? 18.409  14.847  37.233  1.00 15.45 ? 261 ALA   B C    1 
ATOM   8642  O  O    . ALA   B 1 262 ? 17.297  15.340  36.997  1.00 17.59 ? 261 ALA   B O    1 
ATOM   8643  C  CB   . ALA   B 1 262 ? 18.468  12.651  38.378  1.00 20.23 ? 261 ALA   B CB   1 
ATOM   8644  H  H    . ALA   B 1 262 ? 17.085  15.047  39.297  1.00 23.38 ? 261 ALA   B H    1 
ATOM   8645  H  HA   . ALA   B 1 262 ? 19.603  14.329  38.811  1.00 21.42 ? 261 ALA   B HA   1 
ATOM   8646  H  HB1  . ALA   B 1 262 ? 18.638  12.413  37.454  1.00 24.27 ? 261 ALA   B HB1  1 
ATOM   8647  H  HB2  . ALA   B 1 262 ? 19.080  12.174  38.961  1.00 24.27 ? 261 ALA   B HB2  1 
ATOM   8648  H  HB3  . ALA   B 1 262 ? 17.552  12.434  38.612  1.00 24.27 ? 261 ALA   B HB3  1 
ATOM   8649  N  N    . SER   B 1 263 ? 19.432  14.810  36.365  1.00 18.88 ? 262 SER   B N    1 
ATOM   8650  C  CA   . SER   B 1 263 ? 19.372  15.365  35.008  1.00 17.79 ? 262 SER   B CA   1 
ATOM   8651  C  C    . SER   B 1 263 ? 19.235  14.230  34.007  1.00 14.78 ? 262 SER   B C    1 
ATOM   8652  O  O    . SER   B 1 263 ? 20.152  13.410  33.865  1.00 20.68 ? 262 SER   B O    1 
ATOM   8653  C  CB   . SER   B 1 263 ? 20.628  16.174  34.680  1.00 20.00 ? 262 SER   B CB   1 
ATOM   8654  O  OG   . SER   B 1 263 ? 20.822  17.240  35.587  1.00 23.88 ? 262 SER   B OG   1 
ATOM   8655  H  H    . SER   B 1 263 ? 20.195  14.456  36.547  1.00 22.65 ? 262 SER   B H    1 
ATOM   8656  H  HA   . SER   B 1 263 ? 18.592  15.940  34.956  1.00 21.35 ? 262 SER   B HA   1 
ATOM   8657  H  HB2  . SER   B 1 263 ? 21.397  15.585  34.722  1.00 24.01 ? 262 SER   B HB2  1 
ATOM   8658  H  HB3  . SER   B 1 263 ? 20.538  16.539  33.785  1.00 24.01 ? 262 SER   B HB3  1 
ATOM   8659  H  HG   . SER   B 1 263 ? 21.603  17.541  35.513  1.00 28.66 ? 262 SER   B HG   1 
ATOM   8660  N  N    . GLU   B 1 264 ? 18.098  14.187  33.336  1.00 17.32 ? 263 GLU   B N    1 
ATOM   8661  C  CA   . GLU   B 1 264 ? 17.902  13.338  32.161  1.00 18.09 ? 263 GLU   B CA   1 
ATOM   8662  C  C    . GLU   B 1 264 ? 18.367  14.128  30.943  1.00 15.87 ? 263 GLU   B C    1 
ATOM   8663  O  O    . GLU   B 1 264 ? 18.086  15.325  30.821  1.00 16.62 ? 263 GLU   B O    1 
ATOM   8664  C  CB   . GLU   B 1 264 ? 16.436  12.925  32.001  1.00 17.63 ? 263 GLU   B CB   1 
ATOM   8665  C  CG   . GLU   B 1 264 ? 16.150  12.109  30.742  1.00 21.31 ? 263 GLU   B CG   1 
ATOM   8666  C  CD   . GLU   B 1 264 ? 14.706  11.997  30.412  1.00 27.18 ? 263 GLU   B CD   1 
ATOM   8667  O  OE1  . GLU   B 1 264 ? 13.991  11.279  31.131  1.00 29.38 ? 263 GLU   B OE1  1 
ATOM   8668  O  OE2  . GLU   B 1 264 ? 14.284  12.634  29.428  1.00 25.22 ? 263 GLU   B OE2  1 
ATOM   8669  H  H    . GLU   B 1 264 ? 17.403  14.649  33.542  1.00 20.79 ? 263 GLU   B H    1 
ATOM   8670  H  HA   . GLU   B 1 264 ? 18.410  12.516  32.244  1.00 21.71 ? 263 GLU   B HA   1 
ATOM   8671  H  HB2  . GLU   B 1 264 ? 16.181  12.385  32.766  1.00 21.16 ? 263 GLU   B HB2  1 
ATOM   8672  H  HB3  . GLU   B 1 264 ? 15.890  13.726  31.963  1.00 21.16 ? 263 GLU   B HB3  1 
ATOM   8673  H  HG2  . GLU   B 1 264 ? 16.593  12.531  29.989  1.00 25.58 ? 263 GLU   B HG2  1 
ATOM   8674  H  HG3  . GLU   B 1 264 ? 16.495  11.211  30.868  1.00 25.58 ? 263 GLU   B HG3  1 
ATOM   8675  N  N    . TYR   B 1 265 ? 19.063  13.441  30.040  1.00 19.57 ? 264 TYR   B N    1 
ATOM   8676  C  CA   . TYR   B 1 265 ? 19.510  14.057  28.795  1.00 15.56 ? 264 TYR   B CA   1 
ATOM   8677  C  C    . TYR   B 1 265 ? 19.277  13.092  27.651  1.00 17.63 ? 264 TYR   B C    1 
ATOM   8678  O  O    . TYR   B 1 265 ? 19.799  11.973  27.652  1.00 18.80 ? 264 TYR   B O    1 
ATOM   8679  C  CB   . TYR   B 1 265 ? 20.987  14.422  28.848  1.00 15.86 ? 264 TYR   B CB   1 
ATOM   8680  C  CG   . TYR   B 1 265 ? 21.489  15.151  27.625  1.00 17.39 ? 264 TYR   B CG   1 
ATOM   8681  C  CD1  . TYR   B 1 265 ? 21.379  16.520  27.522  1.00 18.42 ? 264 TYR   B CD1  1 
ATOM   8682  C  CD2  . TYR   B 1 265 ? 22.074  14.457  26.580  1.00 19.23 ? 264 TYR   B CD2  1 
ATOM   8683  C  CE1  . TYR   B 1 265 ? 21.857  17.195  26.415  1.00 18.00 ? 264 TYR   B CE1  1 
ATOM   8684  C  CE2  . TYR   B 1 265 ? 22.540  15.137  25.454  1.00 16.35 ? 264 TYR   B CE2  1 
ATOM   8685  C  CZ   . TYR   B 1 265 ? 22.417  16.495  25.389  1.00 19.22 ? 264 TYR   B CZ   1 
ATOM   8686  O  OH   . TYR   B 1 265 ? 22.895  17.209  24.311  1.00 20.73 ? 264 TYR   B OH   1 
ATOM   8687  H  H    . TYR   B 1 265 ? 19.288  12.616  30.127  1.00 23.48 ? 264 TYR   B H    1 
ATOM   8688  H  HA   . TYR   B 1 265 ? 18.994  14.864  28.641  1.00 18.68 ? 264 TYR   B HA   1 
ATOM   8689  H  HB2  . TYR   B 1 265 ? 21.136  14.996  29.615  1.00 19.03 ? 264 TYR   B HB2  1 
ATOM   8690  H  HB3  . TYR   B 1 265 ? 21.504  13.607  28.938  1.00 19.03 ? 264 TYR   B HB3  1 
ATOM   8691  H  HD1  . TYR   B 1 265 ? 20.975  16.999  28.209  1.00 22.10 ? 264 TYR   B HD1  1 
ATOM   8692  H  HD2  . TYR   B 1 265 ? 22.158  13.532  26.628  1.00 23.07 ? 264 TYR   B HD2  1 
ATOM   8693  H  HE1  . TYR   B 1 265 ? 21.797  18.122  26.371  1.00 21.60 ? 264 TYR   B HE1  1 
ATOM   8694  H  HE2  . TYR   B 1 265 ? 22.931  14.669  24.752  1.00 19.62 ? 264 TYR   B HE2  1 
ATOM   8695  H  HH   . TYR   B 1 265 ? 23.556  16.815  23.975  1.00 24.87 ? 264 TYR   B HH   1 
ATOM   8696  N  N    . THR   B 1 266 ? 18.562  13.563  26.640  1.00 22.23 ? 265 THR   B N    1 
ATOM   8697  C  CA   . THR   B 1 266 ? 18.327  12.776  25.444  1.00 19.91 ? 265 THR   B CA   1 
ATOM   8698  C  C    . THR   B 1 266 ? 18.938  13.521  24.271  1.00 21.28 ? 265 THR   B C    1 
ATOM   8699  O  O    . THR   B 1 266 ? 18.886  14.746  24.223  1.00 20.46 ? 265 THR   B O    1 
ATOM   8700  C  CB   . THR   B 1 266 ? 16.834  12.565  25.228  1.00 25.97 ? 265 THR   B CB   1 
ATOM   8701  O  OG1  . THR   B 1 266 ? 16.201  13.842  25.172  1.00 32.03 ? 265 THR   B OG1  1 
ATOM   8702  C  CG2  . THR   B 1 266 ? 16.212  11.744  26.366  1.00 24.78 ? 265 THR   B CG2  1 
ATOM   8703  H  H    . THR   B 1 266 ? 18.200  14.343  26.626  1.00 26.68 ? 265 THR   B H    1 
ATOM   8704  H  HA   . THR   B 1 266 ? 18.740  11.901  25.508  1.00 23.89 ? 265 THR   B HA   1 
ATOM   8705  H  HB   . THR   B 1 266 ? 16.691  12.075  24.404  1.00 31.17 ? 265 THR   B HB   1 
ATOM   8706  H  HG1  . THR   B 1 266 ? 16.278  14.234  25.911  1.00 38.44 ? 265 THR   B HG1  1 
ATOM   8707  H  HG21 . THR   B 1 266 ? 15.260  11.924  26.423  1.00 29.74 ? 265 THR   B HG21 1 
ATOM   8708  H  HG22 . THR   B 1 266 ? 16.344  10.797  26.203  1.00 29.74 ? 265 THR   B HG22 1 
ATOM   8709  H  HG23 . THR   B 1 266 ? 16.627  11.979  27.211  1.00 29.74 ? 265 THR   B HG23 1 
ATOM   8710  N  N    . GLY   B 1 267 ? 19.499  12.776  23.320  1.00 24.59 ? 266 GLY   B N    1 
ATOM   8711  C  CA   . GLY   B 1 267 ? 20.007  13.380  22.104  1.00 25.13 ? 266 GLY   B CA   1 
ATOM   8712  C  C    . GLY   B 1 267 ? 21.516  13.286  21.986  1.00 28.62 ? 266 GLY   B C    1 
ATOM   8713  O  O    . GLY   B 1 267 ? 22.200  12.559  22.707  1.00 22.92 ? 266 GLY   B O    1 
ATOM   8714  H  H    . GLY   B 1 267 ? 19.593  11.922  23.362  1.00 29.51 ? 266 GLY   B H    1 
ATOM   8715  H  HA2  . GLY   B 1 267 ? 19.615  12.933  21.338  1.00 30.16 ? 266 GLY   B HA2  1 
ATOM   8716  H  HA3  . GLY   B 1 267 ? 19.759  14.317  22.085  1.00 30.16 ? 266 GLY   B HA3  1 
ATOM   8717  N  N    . ASN   B 1 268 ? 22.036  14.024  21.021  1.00 22.89 ? 267 ASN   B N    1 
ATOM   8718  C  CA   . ASN   B 1 268 ? 23.460  13.992  20.753  1.00 22.65 ? 267 ASN   B CA   1 
ATOM   8719  C  C    . ASN   B 1 268 ? 24.166  15.035  21.601  1.00 16.73 ? 267 ASN   B C    1 
ATOM   8720  O  O    . ASN   B 1 268 ? 23.584  16.037  22.027  1.00 18.07 ? 267 ASN   B O    1 
ATOM   8721  C  CB   . ASN   B 1 268 ? 23.762  14.267  19.260  1.00 22.85 ? 267 ASN   B CB   1 
ATOM   8722  C  CG   . ASN   B 1 268 ? 23.590  13.036  18.384  1.00 27.24 ? 267 ASN   B CG   1 
ATOM   8723  O  OD1  . ASN   B 1 268 ? 22.496  12.459  18.320  1.00 29.17 ? 267 ASN   B OD1  1 
ATOM   8724  N  ND2  . ASN   B 1 268 ? 24.663  12.633  17.690  1.00 25.69 ? 267 ASN   B ND2  1 
ATOM   8725  H  H    . ASN   B 1 268 ? 21.586  14.550  20.510  1.00 27.47 ? 267 ASN   B H    1 
ATOM   8726  H  HA   . ASN   B 1 268 ? 23.800  13.109  20.968  1.00 27.18 ? 267 ASN   B HA   1 
ATOM   8727  H  HB2  . ASN   B 1 268 ? 23.155  14.951  18.936  1.00 27.42 ? 267 ASN   B HB2  1 
ATOM   8728  H  HB3  . ASN   B 1 268 ? 24.679  14.569  19.174  1.00 27.42 ? 267 ASN   B HB3  1 
ATOM   8729  H  HD21 . ASN   B 1 268 ? 24.611  11.942  17.182  1.00 30.83 ? 267 ASN   B HD21 1 
ATOM   8730  H  HD22 . ASN   B 1 268 ? 25.403  13.067  17.753  1.00 30.83 ? 267 ASN   B HD22 1 
ATOM   8731  N  N    . TYR   B 1 269 ? 25.463  14.831  21.763  1.00 17.83 ? 268 TYR   B N    1 
ATOM   8732  C  CA   . TYR   B 1 269 ? 26.313  15.804  22.424  1.00 19.69 ? 268 TYR   B CA   1 
ATOM   8733  C  C    . TYR   B 1 269 ? 26.059  17.206  21.906  1.00 22.11 ? 268 TYR   B C    1 
ATOM   8734  O  O    . TYR   B 1 269 ? 26.118  17.464  20.706  1.00 20.14 ? 268 TYR   B O    1 
ATOM   8735  C  CB   . TYR   B 1 269 ? 27.747  15.397  22.168  1.00 24.40 ? 268 TYR   B CB   1 
ATOM   8736  C  CG   . TYR   B 1 269 ? 28.840  16.139  22.867  1.00 23.98 ? 268 TYR   B CG   1 
ATOM   8737  C  CD1  . TYR   B 1 269 ? 29.036  15.999  24.234  1.00 24.15 ? 268 TYR   B CD1  1 
ATOM   8738  C  CD2  . TYR   B 1 269 ? 29.726  16.921  22.160  1.00 27.11 ? 268 TYR   B CD2  1 
ATOM   8739  C  CE1  . TYR   B 1 269 ? 30.081  16.623  24.865  1.00 24.95 ? 268 TYR   B CE1  1 
ATOM   8740  C  CE2  . TYR   B 1 269 ? 30.789  17.569  22.796  1.00 25.38 ? 268 TYR   B CE2  1 
ATOM   8741  C  CZ   . TYR   B 1 269 ? 30.956  17.404  24.144  1.00 30.11 ? 268 TYR   B CZ   1 
ATOM   8742  O  OH   . TYR   B 1 269 ? 31.996  18.038  24.777  1.00 31.57 ? 268 TYR   B OH   1 
ATOM   8743  H  H    . TYR   B 1 269 ? 25.880  14.128  21.496  1.00 21.39 ? 268 TYR   B H    1 
ATOM   8744  H  HA   . TYR   B 1 269 ? 26.134  15.821  23.378  1.00 23.63 ? 268 TYR   B HA   1 
ATOM   8745  H  HB2  . TYR   B 1 269 ? 27.838  14.466  22.426  1.00 29.28 ? 268 TYR   B HB2  1 
ATOM   8746  H  HB3  . TYR   B 1 269 ? 27.914  15.495  21.217  1.00 29.28 ? 268 TYR   B HB3  1 
ATOM   8747  H  HD1  . TYR   B 1 269 ? 28.449  15.474  24.730  1.00 28.98 ? 268 TYR   B HD1  1 
ATOM   8748  H  HD2  . TYR   B 1 269 ? 29.615  17.021  21.242  1.00 32.53 ? 268 TYR   B HD2  1 
ATOM   8749  H  HE1  . TYR   B 1 269 ? 30.199  16.519  25.782  1.00 29.94 ? 268 TYR   B HE1  1 
ATOM   8750  H  HE2  . TYR   B 1 269 ? 31.374  18.104  22.310  1.00 30.45 ? 268 TYR   B HE2  1 
ATOM   8751  H  HH   . TYR   B 1 269 ? 32.055  17.769  25.571  1.00 37.88 ? 268 TYR   B HH   1 
ATOM   8752  N  N    . GLN   B 1 270 ? 25.791  18.129  22.825  1.00 16.45 ? 269 GLN   B N    1 
ATOM   8753  C  CA   . GLN   B 1 270 ? 25.657  19.542  22.565  1.00 16.78 ? 269 GLN   B CA   1 
ATOM   8754  C  C    . GLN   B 1 270 ? 24.403  19.930  21.807  1.00 21.06 ? 269 GLN   B C    1 
ATOM   8755  O  O    . GLN   B 1 270 ? 24.249  21.117  21.473  1.00 22.69 ? 269 GLN   B O    1 
ATOM   8756  C  CB   . GLN   B 1 270 ? 26.915  20.065  21.849  1.00 22.88 ? 269 GLN   B CB   1 
ATOM   8757  C  CG   . GLN   B 1 270 ? 27.818  20.824  22.780  1.00 35.09 ? 269 GLN   B CG   1 
ATOM   8758  C  CD   . GLN   B 1 270 ? 28.875  21.710  22.105  1.00 33.25 ? 269 GLN   B CD   1 
ATOM   8759  O  OE1  . GLN   B 1 270 ? 29.880  21.203  21.644  1.00 35.56 ? 269 GLN   B OE1  1 
ATOM   8760  N  NE2  . GLN   B 1 270 ? 28.663  23.041  22.113  1.00 34.22 ? 269 GLN   B NE2  1 
ATOM   8761  H  H    . GLN   B 1 270 ? 25.677  17.937  23.656  1.00 19.74 ? 269 GLN   B H    1 
ATOM   8762  H  HA   . GLN   B 1 270 ? 25.568  19.998  23.417  1.00 20.14 ? 269 GLN   B HA   1 
ATOM   8763  H  HB2  . GLN   B 1 270 ? 27.412  19.314  21.489  1.00 27.45 ? 269 GLN   B HB2  1 
ATOM   8764  H  HB3  . GLN   B 1 270 ? 26.648  20.661  21.131  1.00 27.45 ? 269 GLN   B HB3  1 
ATOM   8765  H  HG2  . GLN   B 1 270 ? 27.270  21.402  23.333  1.00 42.11 ? 269 GLN   B HG2  1 
ATOM   8766  H  HG3  . GLN   B 1 270 ? 28.291  20.185  23.335  1.00 42.11 ? 269 GLN   B HG3  1 
ATOM   8767  H  HE21 . GLN   B 1 270 ? 27.958  23.362  22.487  1.00 41.06 ? 269 GLN   B HE21 1 
ATOM   8768  H  HE22 . GLN   B 1 270 ? 29.233  23.570  21.745  1.00 41.06 ? 269 GLN   B HE22 1 
ATOM   8769  N  N    . CYS   B 1 271 ? 23.522  19.011  21.509  1.00 21.93 ? 270 CYS   B N    1 
ATOM   8770  C  CA   . CYS   B 1 271 ? 22.370  19.462  20.778  1.00 20.09 ? 270 CYS   B CA   1 
ATOM   8771  C  C    . CYS   B 1 271 ? 21.101  18.903  21.241  1.00 22.56 ? 270 CYS   B C    1 
ATOM   8772  O  O    . CYS   B 1 271 ? 20.121  19.036  20.508  1.00 21.09 ? 270 CYS   B O    1 
ATOM   8773  C  CB   . CYS   B 1 271 ? 22.550  19.069  19.311  1.00 34.67 ? 270 CYS   B CB   1 
ATOM   8774  S  SG   . CYS   B 1 271 ? 23.869  17.866  19.022  1.00 35.80 ? 270 CYS   B SG   1 
ATOM   8775  H  H    . CYS   B 1 271 ? 23.596  18.169  21.668  1.00 26.32 ? 270 CYS   B H    1 
ATOM   8776  H  HA   . CYS   B 1 271 ? 22.313  20.439  20.831  1.00 24.11 ? 270 CYS   B HA   1 
ATOM   8777  H  HB2  . CYS   B 1 271 ? 21.722  18.682  18.987  1.00 41.60 ? 270 CYS   B HB2  1 
ATOM   8778  H  HB3  . CYS   B 1 271 ? 22.760  19.865  18.799  1.00 41.60 ? 270 CYS   B HB3  1 
ATOM   8779  N  N    . GLY   B 1 272 ? 20.975  18.230  22.467  1.00 19.49 ? 271 GLY   B N    1 
ATOM   8780  C  CA   . GLY   B 1 272 ? 19.857  17.454  22.949  1.00 20.60 ? 271 GLY   B CA   1 
ATOM   8781  C  C    . GLY   B 1 272 ? 18.912  18.213  23.866  1.00 22.86 ? 271 GLY   B C    1 
ATOM   8782  O  O    . GLY   B 1 272 ? 18.680  19.414  23.702  1.00 20.96 ? 271 GLY   B O    1 
ATOM   8783  H  H    . GLY   B 1 272 ? 21.588  18.364  23.055  1.00 23.38 ? 271 GLY   B H    1 
ATOM   8784  H  HA2  . GLY   B 1 272 ? 19.344  17.139  22.189  1.00 24.72 ? 271 GLY   B HA2  1 
ATOM   8785  H  HA3  . GLY   B 1 272 ? 20.196  16.689  23.440  1.00 24.72 ? 271 GLY   B HA3  1 
ATOM   8786  N  N    . HIS   B 1 273 ? 18.317  17.495  24.810  1.00 19.97 ? 272 HIS   B N    1 
ATOM   8787  C  CA   . HIS   B 1 273 ? 17.260  18.051  25.626  1.00 19.60 ? 272 HIS   B CA   1 
ATOM   8788  C  C    . HIS   B 1 273 ? 17.404  17.511  27.043  1.00 17.81 ? 272 HIS   B C    1 
ATOM   8789  O  O    . HIS   B 1 273 ? 17.476  16.302  27.246  1.00 17.03 ? 272 HIS   B O    1 
ATOM   8790  C  CB   . HIS   B 1 273 ? 15.877  17.698  25.058  1.00 19.30 ? 272 HIS   B CB   1 
ATOM   8791  C  CG   . HIS   B 1 273 ? 14.759  18.347  25.787  1.00 22.55 ? 272 HIS   B CG   1 
ATOM   8792  N  ND1  . HIS   B 1 273 ? 14.509  19.697  25.704  1.00 20.16 ? 272 HIS   B ND1  1 
ATOM   8793  C  CD2  . HIS   B 1 273 ? 13.817  17.834  26.610  1.00 21.45 ? 272 HIS   B CD2  1 
ATOM   8794  C  CE1  . HIS   B 1 273 ? 13.471  19.994  26.470  1.00 27.03 ? 272 HIS   B CE1  1 
ATOM   8795  N  NE2  . HIS   B 1 273 ? 13.035  18.878  27.030  1.00 21.80 ? 272 HIS   B NE2  1 
ATOM   8796  H  H    . HIS   B 1 273 ? 18.513  16.678  24.995  1.00 23.96 ? 272 HIS   B H    1 
ATOM   8797  H  HA   . HIS   B 1 273 ? 17.337  19.017  25.655  1.00 23.52 ? 272 HIS   B HA   1 
ATOM   8798  H  HB2  . HIS   B 1 273 ? 15.836  17.986  24.132  1.00 23.15 ? 272 HIS   B HB2  1 
ATOM   8799  H  HB3  . HIS   B 1 273 ? 15.751  16.738  25.112  1.00 23.15 ? 272 HIS   B HB3  1 
ATOM   8800  H  HD2  . HIS   B 1 273 ? 13.718  16.940  26.847  1.00 25.74 ? 272 HIS   B HD2  1 
ATOM   8801  H  HE1  . HIS   B 1 273 ? 13.110  20.842  26.593  1.00 32.44 ? 272 HIS   B HE1  1 
ATOM   8802  H  HE2  . HIS   B 1 273 ? 12.368  18.817  27.569  1.00 26.16 ? 272 HIS   B HE2  1 
ATOM   8803  N  N    . TYR   B 1 274 ? 17.420  18.413  28.000  1.00 15.55 ? 273 TYR   B N    1 
ATOM   8804  C  CA   . TYR   B 1 274 ? 17.382  18.031  29.410  1.00 15.83 ? 273 TYR   B CA   1 
ATOM   8805  C  C    . TYR   B 1 274 ? 15.955  18.006  29.949  1.00 17.22 ? 273 TYR   B C    1 
ATOM   8806  O  O    . TYR   B 1 274 ? 15.120  18.856  29.612  1.00 19.06 ? 273 TYR   B O    1 
ATOM   8807  C  CB   . TYR   B 1 274 ? 18.195  19.017  30.224  1.00 15.01 ? 273 TYR   B CB   1 
ATOM   8808  C  CG   . TYR   B 1 274 ? 19.693  18.897  30.210  1.00 14.24 ? 273 TYR   B CG   1 
ATOM   8809  C  CD1  . TYR   B 1 274 ? 20.348  17.993  31.028  1.00 16.66 ? 273 TYR   B CD1  1 
ATOM   8810  C  CD2  . TYR   B 1 274 ? 20.464  19.770  29.432  1.00 16.85 ? 273 TYR   B CD2  1 
ATOM   8811  C  CE1  . TYR   B 1 274 ? 21.756  17.921  31.056  1.00 16.89 ? 273 TYR   B CE1  1 
ATOM   8812  C  CE2  . TYR   B 1 274 ? 21.875  19.710  29.452  1.00 15.96 ? 273 TYR   B CE2  1 
ATOM   8813  C  CZ   . TYR   B 1 274 ? 22.503  18.772  30.254  1.00 14.64 ? 273 TYR   B CZ   1 
ATOM   8814  O  OH   . TYR   B 1 274 ? 23.868  18.712  30.334  1.00 18.09 ? 273 TYR   B OH   1 
ATOM   8815  H  H    . TYR   B 1 274 ? 17.452  19.262  27.866  1.00 18.66 ? 273 TYR   B H    1 
ATOM   8816  H  HA   . TYR   B 1 274 ? 17.749  17.138  29.504  1.00 19.00 ? 273 TYR   B HA   1 
ATOM   8817  H  HB2  . TYR   B 1 274 ? 17.987  19.907  29.900  1.00 18.01 ? 273 TYR   B HB2  1 
ATOM   8818  H  HB3  . TYR   B 1 274 ? 17.921  18.929  31.151  1.00 18.01 ? 273 TYR   B HB3  1 
ATOM   8819  H  HD1  . TYR   B 1 274 ? 19.851  17.423  31.569  1.00 19.99 ? 273 TYR   B HD1  1 
ATOM   8820  H  HD2  . TYR   B 1 274 ? 20.040  20.399  28.894  1.00 20.22 ? 273 TYR   B HD2  1 
ATOM   8821  H  HE1  . TYR   B 1 274 ? 22.181  17.307  31.609  1.00 20.26 ? 273 TYR   B HE1  1 
ATOM   8822  H  HE2  . TYR   B 1 274 ? 22.378  20.294  28.933  1.00 19.15 ? 273 TYR   B HE2  1 
ATOM   8823  H  HH   . TYR   B 1 274 ? 24.099  18.092  30.852  1.00 21.70 ? 273 TYR   B HH   1 
ATOM   8824  N  N    . LYS   B 1 275 ? 15.722  17.064  30.878  1.00 18.71 ? 274 LYS   B N    1 
ATOM   8825  C  CA   . LYS   B 1 275 ? 14.548  17.012  31.735  1.00 19.20 ? 274 LYS   B CA   1 
ATOM   8826  C  C    . LYS   B 1 275 ? 15.072  16.834  33.160  1.00 18.54 ? 274 LYS   B C    1 
ATOM   8827  O  O    . LYS   B 1 275 ? 16.219  16.451  33.371  1.00 19.11 ? 274 LYS   B O    1 
ATOM   8828  C  CB   . LYS   B 1 275 ? 13.627  15.855  31.333  1.00 23.37 ? 274 LYS   B CB   1 
ATOM   8829  C  CG   . LYS   B 1 275 ? 12.978  15.999  29.914  1.00 20.96 ? 274 LYS   B CG   1 
ATOM   8830  C  CD   . LYS   B 1 275 ? 11.823  15.004  29.697  1.00 22.93 ? 274 LYS   B CD   1 
ATOM   8831  C  CE   . LYS   B 1 275 ? 11.534  14.823  28.209  1.00 33.52 ? 274 LYS   B CE   1 
ATOM   8832  N  NZ   . LYS   B 1 275 ? 10.519  13.759  27.977  1.00 37.44 ? 274 LYS   B NZ   1 
ATOM   8833  H  H    . LYS   B 1 275 ? 16.264  16.415  31.032  1.00 22.45 ? 274 LYS   B H    1 
ATOM   8834  H  HA   . LYS   B 1 275 ? 14.016  17.821  31.683  1.00 23.04 ? 274 LYS   B HA   1 
ATOM   8835  H  HB2  . LYS   B 1 275 ? 14.143  15.034  31.336  1.00 28.05 ? 274 LYS   B HB2  1 
ATOM   8836  H  HB3  . LYS   B 1 275 ? 12.906  15.796  31.980  1.00 28.05 ? 274 LYS   B HB3  1 
ATOM   8837  H  HG2  . LYS   B 1 275 ? 12.625  16.897  29.815  1.00 25.15 ? 274 LYS   B HG2  1 
ATOM   8838  H  HG3  . LYS   B 1 275 ? 13.652  15.832  29.237  1.00 25.15 ? 274 LYS   B HG3  1 
ATOM   8839  H  HD2  . LYS   B 1 275 ? 12.064  14.142  30.070  1.00 27.52 ? 274 LYS   B HD2  1 
ATOM   8840  H  HD3  . LYS   B 1 275 ? 11.021  15.340  30.127  1.00 27.52 ? 274 LYS   B HD3  1 
ATOM   8841  H  HE2  . LYS   B 1 275 ? 11.192  15.655  27.844  1.00 40.22 ? 274 LYS   B HE2  1 
ATOM   8842  H  HE3  . LYS   B 1 275 ? 12.351  14.571  27.751  1.00 40.22 ? 274 LYS   B HE3  1 
ATOM   8843  H  HZ1  . LYS   B 1 275 ? 10.319  13.712  27.111  1.00 44.92 ? 274 LYS   B HZ1  1 
ATOM   8844  H  HZ2  . LYS   B 1 275 ? 10.837  12.972  28.243  1.00 44.92 ? 274 LYS   B HZ2  1 
ATOM   8845  H  HZ3  . LYS   B 1 275 ? 9.778   13.941  28.435  1.00 44.92 ? 274 LYS   B HZ3  1 
ATOM   8846  N  N    . HIS   B 1 276 ? 14.232  17.136  34.133  1.00 20.47 ? 275 HIS   B N    1 
ATOM   8847  C  CA   . HIS   B 1 276 ? 14.612  17.131  35.545  1.00 18.23 ? 275 HIS   B CA   1 
ATOM   8848  C  C    . HIS   B 1 276 ? 13.763  16.101  36.272  1.00 16.74 ? 275 HIS   B C    1 
ATOM   8849  O  O    . HIS   B 1 276 ? 12.531  16.141  36.184  1.00 21.71 ? 275 HIS   B O    1 
ATOM   8850  C  CB   . HIS   B 1 276 ? 14.402  18.511  36.140  1.00 18.52 ? 275 HIS   B CB   1 
ATOM   8851  C  CG   . HIS   B 1 276 ? 14.746  18.587  37.587  1.00 17.22 ? 275 HIS   B CG   1 
ATOM   8852  N  ND1  . HIS   B 1 276 ? 16.035  18.798  38.028  1.00 20.00 ? 275 HIS   B ND1  1 
ATOM   8853  C  CD2  . HIS   B 1 276 ? 13.976  18.451  38.693  1.00 21.29 ? 275 HIS   B CD2  1 
ATOM   8854  C  CE1  . HIS   B 1 276 ? 16.046  18.788  39.355  1.00 20.83 ? 275 HIS   B CE1  1 
ATOM   8855  N  NE2  . HIS   B 1 276 ? 14.811  18.583  39.778  1.00 19.82 ? 275 HIS   B NE2  1 
ATOM   8856  H  H    . HIS   B 1 276 ? 13.411  17.355  34.002  1.00 24.56 ? 275 HIS   B H    1 
ATOM   8857  H  HA   . HIS   B 1 276 ? 15.544  16.880  35.644  1.00 21.88 ? 275 HIS   B HA   1 
ATOM   8858  H  HB2  . HIS   B 1 276 ? 14.964  19.145  35.667  1.00 22.22 ? 275 HIS   B HB2  1 
ATOM   8859  H  HB3  . HIS   B 1 276 ? 13.469  18.757  36.042  1.00 22.22 ? 275 HIS   B HB3  1 
ATOM   8860  H  HD1  . HIS   B 1 276 ? 16.722  18.916  37.524  1.00 24.00 ? 275 HIS   B HD1  1 
ATOM   8861  H  HD2  . HIS   B 1 276 ? 13.059  18.299  38.715  1.00 25.55 ? 275 HIS   B HD2  1 
ATOM   8862  H  HE1  . HIS   B 1 276 ? 16.794  18.906  39.895  1.00 24.99 ? 275 HIS   B HE1  1 
ATOM   8863  N  N    . ILE   B 1 277 ? 14.404  15.172  36.960  1.00 20.07 ? 276 ILE   B N    1 
ATOM   8864  C  CA   . ILE   B 1 277 ? 13.707  14.147  37.723  1.00 17.57 ? 276 ILE   B CA   1 
ATOM   8865  C  C    . ILE   B 1 277 ? 13.902  14.483  39.198  1.00 20.41 ? 276 ILE   B C    1 
ATOM   8866  O  O    . ILE   B 1 277 ? 15.037  14.704  39.625  1.00 19.69 ? 276 ILE   B O    1 
ATOM   8867  C  CB   . ILE   B 1 277 ? 14.233  12.738  37.427  1.00 18.20 ? 276 ILE   B CB   1 
ATOM   8868  C  CG1  . ILE   B 1 277 ? 14.428  12.501  35.912  1.00 27.43 ? 276 ILE   B CG1  1 
ATOM   8869  C  CG2  . ILE   B 1 277 ? 13.313  11.696  38.051  1.00 23.86 ? 276 ILE   B CG2  1 
ATOM   8870  C  CD1  . ILE   B 1 277 ? 13.187  12.633  35.144  1.00 30.78 ? 276 ILE   B CD1  1 
ATOM   8871  H  H    . ILE   B 1 277 ? 15.261  15.112  37.001  1.00 24.08 ? 276 ILE   B H    1 
ATOM   8872  H  HA   . ILE   B 1 277 ? 12.764  14.163  37.498  1.00 21.09 ? 276 ILE   B HA   1 
ATOM   8873  H  HB   . ILE   B 1 277 ? 15.112  12.655  37.829  1.00 21.84 ? 276 ILE   B HB   1 
ATOM   8874  H  HG12 . ILE   B 1 277 ? 15.062  13.151  35.570  1.00 32.92 ? 276 ILE   B HG12 1 
ATOM   8875  H  HG13 . ILE   B 1 277 ? 14.769  11.603  35.776  1.00 32.92 ? 276 ILE   B HG13 1 
ATOM   8876  H  HG21 . ILE   B 1 277 ? 13.485  10.835  37.639  1.00 28.64 ? 276 ILE   B HG21 1 
ATOM   8877  H  HG22 . ILE   B 1 277 ? 13.491  11.648  39.004  1.00 28.64 ? 276 ILE   B HG22 1 
ATOM   8878  H  HG23 . ILE   B 1 277 ? 12.391  11.957  37.900  1.00 28.64 ? 276 ILE   B HG23 1 
ATOM   8879  H  HD11 . ILE   B 1 277 ? 12.692  13.399  35.474  1.00 36.94 ? 276 ILE   B HD11 1 
ATOM   8880  H  HD12 . ILE   B 1 277 ? 13.407  12.760  34.208  1.00 36.94 ? 276 ILE   B HD12 1 
ATOM   8881  H  HD13 . ILE   B 1 277 ? 12.660  11.826  35.254  1.00 36.94 ? 276 ILE   B HD13 1 
ATOM   8882  N  N    . THR   B 1 278 ? 12.808  14.525  39.968  1.00 20.44 ? 277 THR   B N    1 
ATOM   8883  C  CA   . THR   B 1 278 ? 12.928  14.725  41.419  1.00 20.60 ? 277 THR   B CA   1 
ATOM   8884  C  C    . THR   B 1 278 ? 12.142  13.670  42.189  1.00 26.06 ? 277 THR   B C    1 
ATOM   8885  O  O    . THR   B 1 278 ? 11.116  13.165  41.739  1.00 23.09 ? 277 THR   B O    1 
ATOM   8886  C  CB   . THR   B 1 278 ? 12.491  16.141  41.821  1.00 24.96 ? 277 THR   B CB   1 
ATOM   8887  O  OG1  . THR   B 1 278 ? 12.595  16.312  43.252  1.00 26.99 ? 277 THR   B OG1  1 
ATOM   8888  C  CG2  . THR   B 1 278 ? 11.072  16.425  41.409  1.00 22.83 ? 277 THR   B CG2  1 
ATOM   8889  H  H    . THR   B 1 278 ? 12.002  14.441  39.680  1.00 24.53 ? 277 THR   B H    1 
ATOM   8890  H  HA   . THR   B 1 278 ? 13.855  14.610  41.679  1.00 24.72 ? 277 THR   B HA   1 
ATOM   8891  H  HB   . THR   B 1 278 ? 13.073  16.771  41.368  1.00 29.96 ? 277 THR   B HB   1 
ATOM   8892  H  HG1  . THR   B 1 278 ? 13.365  16.099  43.512  1.00 32.39 ? 277 THR   B HG1  1 
ATOM   8893  H  HG21 . THR   B 1 278 ? 10.877  17.368  41.520  1.00 27.40 ? 277 THR   B HG21 1 
ATOM   8894  H  HG22 . THR   B 1 278 ? 10.943  16.184  40.478  1.00 27.40 ? 277 THR   B HG22 1 
ATOM   8895  H  HG23 . THR   B 1 278 ? 10.459  15.910  41.955  1.00 27.40 ? 277 THR   B HG23 1 
ATOM   8896  N  N    . SER   B 1 279 ? 12.649  13.352  43.383  1.00 25.68 ? 278 SER   B N    1 
ATOM   8897  C  CA   . SER   B 1 279 ? 12.066  12.356  44.271  1.00 20.44 ? 278 SER   B CA   1 
ATOM   8898  C  C    . SER   B 1 279 ? 11.451  13.118  45.438  1.00 23.08 ? 278 SER   B C    1 
ATOM   8899  O  O    . SER   B 1 279 ? 12.151  13.868  46.103  1.00 22.52 ? 278 SER   B O    1 
ATOM   8900  C  CB   . SER   B 1 279 ? 13.140  11.388  44.756  1.00 23.90 ? 278 SER   B CB   1 
ATOM   8901  O  OG   . SER   B 1 279 ? 12.591  10.343  45.538  1.00 23.40 ? 278 SER   B OG   1 
ATOM   8902  H  H    . SER   B 1 279 ? 13.358  13.715  43.707  1.00 30.81 ? 278 SER   B H    1 
ATOM   8903  H  HA   . SER   B 1 279 ? 11.377  11.839  43.824  1.00 24.52 ? 278 SER   B HA   1 
ATOM   8904  H  HB2  . SER   B 1 279 ? 13.583  11.001  43.985  1.00 28.68 ? 278 SER   B HB2  1 
ATOM   8905  H  HB3  . SER   B 1 279 ? 13.781  11.878  45.295  1.00 28.68 ? 278 SER   B HB3  1 
ATOM   8906  H  HG   . SER   B 1 279 ? 12.298  9.735   45.039  1.00 28.08 ? 278 SER   B HG   1 
ATOM   8907  N  N    . LYS   B 1 280 ? 10.133  13.010  45.597  1.00 23.25 ? 279 LYS   B N    1 
ATOM   8908  C  CA   . LYS   B 1 280 ? 9.380   13.641  46.684  1.00 29.68 ? 279 LYS   B CA   1 
ATOM   8909  C  C    . LYS   B 1 280 ? 8.596   12.488  47.291  1.00 26.28 ? 279 LYS   B C    1 
ATOM   8910  O  O    . LYS   B 1 280 ? 9.208   11.502  47.722  1.00 29.71 ? 279 LYS   B O    1 
ATOM   8911  C  CB   . LYS   B 1 280 ? 8.543   14.810  46.164  1.00 33.42 ? 279 LYS   B CB   1 
ATOM   8912  C  CG   . LYS   B 1 280 ? 9.431   15.966  45.627  1.00 36.08 ? 279 LYS   B CG   1 
ATOM   8913  C  CD   . LYS   B 1 280 ? 8.715   17.307  45.585  1.00 40.09 ? 279 LYS   B CD   1 
ATOM   8914  C  CE   . LYS   B 1 280 ? 9.609   18.417  45.039  1.00 35.56 ? 279 LYS   B CE   1 
ATOM   8915  N  NZ   . LYS   B 1 280 ? 8.859   19.701  44.837  1.00 42.05 ? 279 LYS   B NZ   1 
ATOM   8916  H  H    . LYS   B 1 280 ? 9.629   12.557  45.068  1.00 27.90 ? 279 LYS   B H    1 
ATOM   8917  H  HA   . LYS   B 1 280 ? 9.917   14.070  47.369  1.00 35.62 ? 279 LYS   B HA   1 
ATOM   8918  H  HB2  . LYS   B 1 280 ? 7.978   14.500  45.440  1.00 40.11 ? 279 LYS   B HB2  1 
ATOM   8919  H  HB3  . LYS   B 1 280 ? 7.997   15.158  46.886  1.00 40.11 ? 279 LYS   B HB3  1 
ATOM   8920  H  HG2  . LYS   B 1 280 ? 10.206  16.060  46.203  1.00 43.30 ? 279 LYS   B HG2  1 
ATOM   8921  H  HG3  . LYS   B 1 280 ? 9.713   15.751  44.724  1.00 43.30 ? 279 LYS   B HG3  1 
ATOM   8922  H  HD2  . LYS   B 1 280 ? 7.937   17.236  45.010  1.00 48.10 ? 279 LYS   B HD2  1 
ATOM   8923  H  HD3  . LYS   B 1 280 ? 8.443   17.552  46.483  1.00 48.10 ? 279 LYS   B HD3  1 
ATOM   8924  H  HE2  . LYS   B 1 280 ? 10.329  18.583  45.667  1.00 42.67 ? 279 LYS   B HE2  1 
ATOM   8925  H  HE3  . LYS   B 1 280 ? 9.972   18.141  44.183  1.00 42.67 ? 279 LYS   B HE3  1 
ATOM   8926  H  HZ1  . LYS   B 1 280 ? 9.286   20.370  45.241  1.00 50.45 ? 279 LYS   B HZ1  1 
ATOM   8927  H  HZ2  . LYS   B 1 280 ? 8.794   19.882  43.969  1.00 50.45 ? 279 LYS   B HZ2  1 
ATOM   8928  H  HZ3  . LYS   B 1 280 ? 8.040   19.632  45.180  1.00 50.45 ? 279 LYS   B HZ3  1 
ATOM   8929  N  N    . GLU   B 1 281 ? 7.264   12.525  47.226  1.00 28.62 ? 280 GLU   B N    1 
ATOM   8930  C  CA   . GLU   B 1 281 ? 6.480   11.362  47.624  1.00 33.70 ? 280 GLU   B CA   1 
ATOM   8931  C  C    . GLU   B 1 281 ? 6.474   10.288  46.546  1.00 34.51 ? 280 GLU   B C    1 
ATOM   8932  O  O    . GLU   B 1 281 ? 6.170   9.130   46.834  1.00 33.52 ? 280 GLU   B O    1 
ATOM   8933  C  CB   . GLU   B 1 281 ? 5.050   11.806  47.949  1.00 31.32 ? 280 GLU   B CB   1 
ATOM   8934  C  CG   . GLU   B 1 281 ? 4.216   11.919  46.694  1.00 45.36 ? 280 GLU   B CG   1 
ATOM   8935  C  CD   . GLU   B 1 281 ? 4.250   13.305  46.071  1.00 33.45 ? 280 GLU   B CD   1 
ATOM   8936  O  OE1  . GLU   B 1 281 ? 3.323   13.585  45.279  1.00 38.91 ? 280 GLU   B OE1  1 
ATOM   8937  O  OE2  . GLU   B 1 281 ? 5.168   14.099  46.378  1.00 30.66 ? 280 GLU   B OE2  1 
ATOM   8938  H  H    . GLU   B 1 281 ? 6.802   13.200  46.960  1.00 34.34 ? 280 GLU   B H    1 
ATOM   8939  H  HA   . GLU   B 1 281 ? 6.855   10.966  48.427  1.00 40.44 ? 280 GLU   B HA   1 
ATOM   8940  H  HB2  . GLU   B 1 281 ? 4.635   11.154  48.535  1.00 37.59 ? 280 GLU   B HB2  1 
ATOM   8941  H  HB3  . GLU   B 1 281 ? 5.073   12.674  48.381  1.00 37.59 ? 280 GLU   B HB3  1 
ATOM   8942  H  HG2  . GLU   B 1 281 ? 4.552   11.289  46.037  1.00 54.43 ? 280 GLU   B HG2  1 
ATOM   8943  H  HG3  . GLU   B 1 281 ? 3.294   11.712  46.911  1.00 54.43 ? 280 GLU   B HG3  1 
ATOM   8944  N  N    . THR   B 1 282 ? 6.755   10.662  45.294  1.00 27.58 ? 281 THR   B N    1 
ATOM   8945  C  CA   . THR   B 1 282 ? 6.938   9.751   44.181  1.00 30.06 ? 281 THR   B CA   1 
ATOM   8946  C  C    . THR   B 1 282 ? 7.928   10.449  43.244  1.00 22.31 ? 281 THR   B C    1 
ATOM   8947  O  O    . THR   B 1 282 ? 8.497   11.483  43.608  1.00 25.10 ? 281 THR   B O    1 
ATOM   8948  C  CB   . THR   B 1 282 ? 5.587   9.404   43.534  1.00 36.76 ? 281 THR   B CB   1 
ATOM   8949  O  OG1  . THR   B 1 282 ? 5.741   8.304   42.635  1.00 32.15 ? 281 THR   B OG1  1 
ATOM   8950  C  CG2  . THR   B 1 282 ? 4.989   10.580  42.808  1.00 33.91 ? 281 THR   B CG2  1 
ATOM   8951  H  H    . THR   B 1 282 ? 6.849   11.485  45.060  1.00 33.10 ? 281 THR   B H    1 
ATOM   8952  H  HA   . THR   B 1 282 ? 7.319   8.907   44.472  1.00 36.07 ? 281 THR   B HA   1 
ATOM   8953  H  HB   . THR   B 1 282 ? 4.966   9.159   44.238  1.00 44.11 ? 281 THR   B HB   1 
ATOM   8954  H  HG1  . THR   B 1 282 ? 5.604   8.557   41.846  1.00 38.58 ? 281 THR   B HG1  1 
ATOM   8955  H  HG21 . THR   B 1 282 ? 4.043   10.429  42.654  1.00 40.69 ? 281 THR   B HG21 1 
ATOM   8956  H  HG22 . THR   B 1 282 ? 5.097   11.386  43.336  1.00 40.69 ? 281 THR   B HG22 1 
ATOM   8957  H  HG23 . THR   B 1 282 ? 5.431   10.702  41.953  1.00 40.69 ? 281 THR   B HG23 1 
ATOM   8958  N  N    . LEU   B 1 283 ? 8.166   9.870   42.077  1.00 29.38 ? 282 LEU   B N    1 
ATOM   8959  C  CA   . LEU   B 1 283 ? 9.083   10.474  41.107  1.00 26.35 ? 282 LEU   B CA   1 
ATOM   8960  C  C    . LEU   B 1 283 ? 8.336   11.395  40.149  1.00 28.94 ? 282 LEU   B C    1 
ATOM   8961  O  O    . LEU   B 1 283 ? 7.336   10.993  39.546  1.00 30.92 ? 282 LEU   B O    1 
ATOM   8962  C  CB   . LEU   B 1 283 ? 9.831   9.386   40.349  1.00 27.54 ? 282 LEU   B CB   1 
ATOM   8963  C  CG   . LEU   B 1 283 ? 10.591  8.381   41.210  1.00 35.45 ? 282 LEU   B CG   1 
ATOM   8964  C  CD1  . LEU   B 1 283 ? 11.228  7.375   40.313  1.00 33.97 ? 282 LEU   B CD1  1 
ATOM   8965  C  CD2  . LEU   B 1 283 ? 11.638  9.061   42.081  1.00 33.35 ? 282 LEU   B CD2  1 
ATOM   8966  H  H    . LEU   B 1 283 ? 7.812   9.130   41.819  1.00 35.26 ? 282 LEU   B H    1 
ATOM   8967  H  HA   . LEU   B 1 283 ? 9.730   11.023  41.576  1.00 31.63 ? 282 LEU   B HA   1 
ATOM   8968  H  HB2  . LEU   B 1 283 ? 9.187   8.886   39.823  1.00 33.05 ? 282 LEU   B HB2  1 
ATOM   8969  H  HB3  . LEU   B 1 283 ? 10.477  9.813   39.765  1.00 33.05 ? 282 LEU   B HB3  1 
ATOM   8970  H  HG   . LEU   B 1 283 ? 9.974   7.941   41.815  1.00 42.54 ? 282 LEU   B HG   1 
ATOM   8971  H  HD11 . LEU   B 1 283 ? 11.374  6.556   40.810  1.00 40.76 ? 282 LEU   B HD11 1 
ATOM   8972  H  HD12 . LEU   B 1 283 ? 10.640  7.205   39.561  1.00 40.76 ? 282 LEU   B HD12 1 
ATOM   8973  H  HD13 . LEU   B 1 283 ? 12.076  7.726   39.997  1.00 40.76 ? 282 LEU   B HD13 1 
ATOM   8974  H  HD21 . LEU   B 1 283 ? 12.365  8.440   42.243  1.00 40.02 ? 282 LEU   B HD21 1 
ATOM   8975  H  HD22 . LEU   B 1 283 ? 11.970  9.847   41.620  1.00 40.02 ? 282 LEU   B HD22 1 
ATOM   8976  H  HD23 . LEU   B 1 283 ? 11.229  9.318   42.922  1.00 40.02 ? 282 LEU   B HD23 1 
ATOM   8977  N  N    . TYR   B 1 284 ? 8.812   12.637  40.044  1.00 25.57 ? 283 TYR   B N    1 
ATOM   8978  C  CA   . TYR   B 1 284 ? 8.266   13.657  39.161  1.00 23.09 ? 283 TYR   B CA   1 
ATOM   8979  C  C    . TYR   B 1 284 ? 9.283   13.939  38.065  1.00 29.25 ? 283 TYR   B C    1 
ATOM   8980  O  O    . TYR   B 1 284 ? 10.494  14.013  38.331  1.00 22.47 ? 283 TYR   B O    1 
ATOM   8981  C  CB   . TYR   B 1 284 ? 7.938   14.926  39.928  1.00 26.85 ? 283 TYR   B CB   1 
ATOM   8982  C  CG   . TYR   B 1 284 ? 6.688   14.797  40.784  1.00 35.73 ? 283 TYR   B CG   1 
ATOM   8983  C  CD1  . TYR   B 1 284 ? 5.427   15.040  40.249  1.00 34.59 ? 283 TYR   B CD1  1 
ATOM   8984  C  CD2  . TYR   B 1 284 ? 6.764   14.407  42.116  1.00 36.40 ? 283 TYR   B CD2  1 
ATOM   8985  C  CE1  . TYR   B 1 284 ? 4.269   14.903  41.021  1.00 35.51 ? 283 TYR   B CE1  1 
ATOM   8986  C  CE2  . TYR   B 1 284 ? 5.620   14.289  42.895  1.00 33.10 ? 283 TYR   B CE2  1 
ATOM   8987  C  CZ   . TYR   B 1 284 ? 4.379   14.535  42.345  1.00 41.82 ? 283 TYR   B CZ   1 
ATOM   8988  O  OH   . TYR   B 1 284 ? 3.232   14.410  43.103  1.00 38.78 ? 283 TYR   B OH   1 
ATOM   8989  H  H    . TYR   B 1 284 ? 9.483   12.922  40.499  1.00 30.68 ? 283 TYR   B H    1 
ATOM   8990  H  HA   . TYR   B 1 284 ? 7.442   13.349  38.751  1.00 27.71 ? 283 TYR   B HA   1 
ATOM   8991  H  HB2  . TYR   B 1 284 ? 8.681   15.141  40.514  1.00 32.21 ? 283 TYR   B HB2  1 
ATOM   8992  H  HB3  . TYR   B 1 284 ? 7.795   15.648  39.296  1.00 32.21 ? 283 TYR   B HB3  1 
ATOM   8993  H  HD1  . TYR   B 1 284 ? 5.353   15.300  39.359  1.00 41.50 ? 283 TYR   B HD1  1 
ATOM   8994  H  HD2  . TYR   B 1 284 ? 7.595   14.222  42.491  1.00 43.67 ? 283 TYR   B HD2  1 
ATOM   8995  H  HE1  . TYR   B 1 284 ? 3.432   15.058  40.645  1.00 42.61 ? 283 TYR   B HE1  1 
ATOM   8996  H  HE2  . TYR   B 1 284 ? 5.691   14.044  43.789  1.00 39.72 ? 283 TYR   B HE2  1 
ATOM   8997  H  HH   . TYR   B 1 284 ? 2.900   13.646  42.998  1.00 46.54 ? 283 TYR   B HH   1 
ATOM   8998  N  N    . CYS   B 1 285 ? 8.800   14.070  36.835  1.00 24.23 ? 284 CYS   B N    1 
ATOM   8999  C  CA   . CYS   B 1 285 ? 9.646   14.490  35.715  1.00 23.04 ? 284 CYS   B CA   1 
ATOM   9000  C  C    . CYS   B 1 285 ? 9.144   15.867  35.307  1.00 24.81 ? 284 CYS   B C    1 
ATOM   9001  O  O    . CYS   B 1 285 ? 8.018   16.007  34.802  1.00 25.61 ? 284 CYS   B O    1 
ATOM   9002  C  CB   . CYS   B 1 285 ? 9.605   13.462  34.588  1.00 21.25 ? 284 CYS   B CB   1 
ATOM   9003  S  SG   . CYS   B 1 285 ? 10.498  14.044  33.087  1.00 26.38 ? 284 CYS   B SG   1 
ATOM   9004  H  H    . CYS   B 1 285 ? 7.981   13.920  36.620  1.00 29.08 ? 284 CYS   B H    1 
ATOM   9005  H  HA   . CYS   B 1 285 ? 10.579  14.568  35.971  1.00 27.65 ? 284 CYS   B HA   1 
ATOM   9006  H  HB2  . CYS   B 1 285 ? 10.023  12.641  34.891  1.00 25.51 ? 284 CYS   B HB2  1 
ATOM   9007  H  HB3  . CYS   B 1 285 ? 8.681   13.294  34.345  1.00 25.51 ? 284 CYS   B HB3  1 
ATOM   9008  H  HG   . CYS   B 1 285 ? 11.347  14.827  33.416  1.00 31.65 ? 284 CYS   B HG   1 
ATOM   9009  N  N    . ILE   B 1 286 ? 9.938   16.887  35.616  1.00 22.27 ? 285 ILE   B N    1 
ATOM   9010  C  CA   . ILE   B 1 286 ? 9.638   18.270  35.291  1.00 20.47 ? 285 ILE   B CA   1 
ATOM   9011  C  C    . ILE   B 1 286 ? 10.358  18.597  33.992  1.00 23.43 ? 285 ILE   B C    1 
ATOM   9012  O  O    . ILE   B 1 286 ? 11.587  18.502  33.908  1.00 20.32 ? 285 ILE   B O    1 
ATOM   9013  C  CB   . ILE   B 1 286 ? 10.047  19.225  36.418  1.00 20.04 ? 285 ILE   B CB   1 
ATOM   9014  C  CG1  . ILE   B 1 286 ? 9.354   18.830  37.728  1.00 27.55 ? 285 ILE   B CG1  1 
ATOM   9015  C  CG2  . ILE   B 1 286 ? 9.675   20.642  36.067  1.00 22.97 ? 285 ILE   B CG2  1 
ATOM   9016  C  CD1  . ILE   B 1 286 ? 9.905   19.510  38.940  1.00 25.55 ? 285 ILE   B CD1  1 
ATOM   9017  H  H    . ILE   B 1 286 ? 10.687  16.796  36.029  1.00 26.73 ? 285 ILE   B H    1 
ATOM   9018  H  HA   . ILE   B 1 286 ? 8.683   18.373  35.155  1.00 24.57 ? 285 ILE   B HA   1 
ATOM   9019  H  HB   . ILE   B 1 286 ? 11.008  19.163  36.530  1.00 24.05 ? 285 ILE   B HB   1 
ATOM   9020  H  HG12 . ILE   B 1 286 ? 8.414   19.060  37.664  1.00 33.06 ? 285 ILE   B HG12 1 
ATOM   9021  H  HG13 . ILE   B 1 286 ? 9.453   17.874  37.856  1.00 33.06 ? 285 ILE   B HG13 1 
ATOM   9022  H  HG21 . ILE   B 1 286 ? 9.694   21.183  36.872  1.00 27.57 ? 285 ILE   B HG21 1 
ATOM   9023  H  HG22 . ILE   B 1 286 ? 10.313  20.986  35.422  1.00 27.57 ? 285 ILE   B HG22 1 
ATOM   9024  H  HG23 . ILE   B 1 286 ? 8.783   20.649  35.685  1.00 27.57 ? 285 ILE   B HG23 1 
ATOM   9025  H  HD11 . ILE   B 1 286 ? 9.800   18.924  39.706  1.00 30.66 ? 285 ILE   B HD11 1 
ATOM   9026  H  HD12 . ILE   B 1 286 ? 10.846  19.699  38.795  1.00 30.66 ? 285 ILE   B HD12 1 
ATOM   9027  H  HD13 . ILE   B 1 286 ? 9.420   20.336  39.086  1.00 30.66 ? 285 ILE   B HD13 1 
ATOM   9028  N  N    . ASP   B 1 287 ? 9.589   18.946  32.980  1.00 22.72 ? 286 ASP   B N    1 
ATOM   9029  C  CA   . ASP   B 1 287 ? 10.099  19.129  31.620  1.00 20.05 ? 286 ASP   B CA   1 
ATOM   9030  C  C    . ASP   B 1 287 ? 9.664   20.538  31.252  1.00 19.47 ? 286 ASP   B C    1 
ATOM   9031  O  O    . ASP   B 1 287 ? 8.651   20.729  30.564  1.00 25.14 ? 286 ASP   B O    1 
ATOM   9032  C  CB   . ASP   B 1 287 ? 9.547   18.083  30.706  1.00 23.94 ? 286 ASP   B CB   1 
ATOM   9033  C  CG   . ASP   B 1 287 ? 9.987   18.275  29.285  1.00 25.22 ? 286 ASP   B CG   1 
ATOM   9034  O  OD1  . ASP   B 1 287 ? 10.944  19.052  29.054  1.00 22.60 ? 286 ASP   B OD1  1 
ATOM   9035  O  OD2  . ASP   B 1 287 ? 9.385   17.621  28.412  1.00 25.79 ? 286 ASP   B OD2  1 
ATOM   9036  H  H    . ASP   B 1 287 ? 8.744   19.088  33.050  1.00 27.26 ? 286 ASP   B H    1 
ATOM   9037  H  HA   . ASP   B 1 287 ? 11.065  19.057  31.575  1.00 24.06 ? 286 ASP   B HA   1 
ATOM   9038  H  HB2  . ASP   B 1 287 ? 9.853   17.211  31.000  1.00 28.73 ? 286 ASP   B HB2  1 
ATOM   9039  H  HB3  . ASP   B 1 287 ? 8.578   18.120  30.729  1.00 28.73 ? 286 ASP   B HB3  1 
ATOM   9040  N  N    . GLY   B 1 288 ? 10.409  21.527  31.748  1.00 20.36 ? 287 GLY   B N    1 
ATOM   9041  C  CA   . GLY   B 1 288 ? 10.022  22.915  31.594  1.00 19.70 ? 287 GLY   B CA   1 
ATOM   9042  C  C    . GLY   B 1 288 ? 8.679   23.193  32.250  1.00 27.16 ? 287 GLY   B C    1 
ATOM   9043  O  O    . GLY   B 1 288 ? 8.552   23.091  33.477  1.00 23.85 ? 287 GLY   B O    1 
ATOM   9044  H  H    . GLY   B 1 288 ? 11.145  21.412  32.179  1.00 24.43 ? 287 GLY   B H    1 
ATOM   9045  H  HA2  . GLY   B 1 288 ? 10.691  23.486  32.003  1.00 23.64 ? 287 GLY   B HA2  1 
ATOM   9046  H  HA3  . GLY   B 1 288 ? 9.956   23.131  30.651  1.00 23.64 ? 287 GLY   B HA3  1 
ATOM   9047  N  N    . ALA   B 1 289 ? 7.664   23.504  31.447  1.00 25.79 ? 288 ALA   B N    1 
ATOM   9048  C  CA   . ALA   B 1 289 ? 6.306   23.726  31.944  1.00 28.82 ? 288 ALA   B CA   1 
ATOM   9049  C  C    . ALA   B 1 289 ? 5.519   22.439  32.161  1.00 23.33 ? 288 ALA   B C    1 
ATOM   9050  O  O    . ALA   B 1 289 ? 4.419   22.489  32.735  1.00 30.76 ? 288 ALA   B O    1 
ATOM   9051  C  CB   . ALA   B 1 289 ? 5.525   24.604  30.960  1.00 27.90 ? 288 ALA   B CB   1 
ATOM   9052  H  H    . ALA   B 1 289 ? 7.735   23.595  30.595  1.00 30.94 ? 288 ALA   B H    1 
ATOM   9053  H  HA   . ALA   B 1 289 ? 6.374   24.185  32.796  1.00 34.59 ? 288 ALA   B HA   1 
ATOM   9054  H  HB1  . ALA   B 1 289 ? 4.794   25.033  31.431  1.00 33.48 ? 288 ALA   B HB1  1 
ATOM   9055  H  HB2  . ALA   B 1 289 ? 6.122   25.276  30.594  1.00 33.48 ? 288 ALA   B HB2  1 
ATOM   9056  H  HB3  . ALA   B 1 289 ? 5.178   24.047  30.246  1.00 33.48 ? 288 ALA   B HB3  1 
ATOM   9057  N  N    . LEU   B 1 290 ? 6.036   21.298  31.730  1.00 23.80 ? 289 LEU   B N    1 
ATOM   9058  C  CA   . LEU   B 1 290 ? 5.297   20.040  31.721  1.00 29.12 ? 289 LEU   B CA   1 
ATOM   9059  C  C    . LEU   B 1 290 ? 5.661   19.160  32.913  1.00 28.99 ? 289 LEU   B C    1 
ATOM   9060  O  O    . LEU   B 1 290 ? 6.811   19.127  33.340  1.00 25.87 ? 289 LEU   B O    1 
ATOM   9061  C  CB   . LEU   B 1 290 ? 5.564   19.269  30.427  1.00 28.00 ? 289 LEU   B CB   1 
ATOM   9062  C  CG   . LEU   B 1 290 ? 5.543   20.079  29.127  1.00 35.93 ? 289 LEU   B CG   1 
ATOM   9063  C  CD1  . LEU   B 1 290 ? 5.835   19.194  27.912  1.00 37.01 ? 289 LEU   B CD1  1 
ATOM   9064  C  CD2  . LEU   B 1 290 ? 4.190   20.776  28.988  1.00 32.36 ? 289 LEU   B CD2  1 
ATOM   9065  H  H    . LEU   B 1 290 ? 6.838   21.222  31.428  1.00 28.55 ? 289 LEU   B H    1 
ATOM   9066  H  HA   . LEU   B 1 290 ? 4.351   20.244  31.787  1.00 34.94 ? 289 LEU   B HA   1 
ATOM   9067  H  HB2  . LEU   B 1 290 ? 6.443   18.864  30.496  1.00 33.60 ? 289 LEU   B HB2  1 
ATOM   9068  H  HB3  . LEU   B 1 290 ? 4.887   18.579  30.344  1.00 33.60 ? 289 LEU   B HB3  1 
ATOM   9069  H  HG   . LEU   B 1 290 ? 6.241   20.752  29.155  1.00 43.11 ? 289 LEU   B HG   1 
ATOM   9070  H  HD11 . LEU   B 1 290 ? 6.000   19.760  27.141  1.00 44.42 ? 289 LEU   B HD11 1 
ATOM   9071  H  HD12 . LEU   B 1 290 ? 6.618   18.652  28.097  1.00 44.42 ? 289 LEU   B HD12 1 
ATOM   9072  H  HD13 . LEU   B 1 290 ? 5.069   18.623  27.745  1.00 44.42 ? 289 LEU   B HD13 1 
ATOM   9073  H  HD21 . LEU   B 1 290 ? 4.028   20.967  28.051  1.00 38.83 ? 289 LEU   B HD21 1 
ATOM   9074  H  HD22 . LEU   B 1 290 ? 3.497   20.191  29.331  1.00 38.83 ? 289 LEU   B HD22 1 
ATOM   9075  H  HD23 . LEU   B 1 290 ? 4.207   21.603  29.496  1.00 38.83 ? 289 LEU   B HD23 1 
ATOM   9076  N  N    . LEU   B 1 291 ? 4.673   18.452  33.450  1.00 26.54 ? 290 LEU   B N    1 
ATOM   9077  C  CA   . LEU   B 1 291 ? 4.882   17.565  34.594  1.00 28.40 ? 290 LEU   B CA   1 
ATOM   9078  C  C    . LEU   B 1 291 ? 4.292   16.178  34.360  1.00 29.71 ? 290 LEU   B C    1 
ATOM   9079  O  O    . LEU   B 1 291 ? 3.129   16.055  33.958  1.00 34.49 ? 290 LEU   B O    1 
ATOM   9080  C  CB   . LEU   B 1 291 ? 4.269   18.206  35.841  1.00 34.66 ? 290 LEU   B CB   1 
ATOM   9081  C  CG   . LEU   B 1 291 ? 4.434   17.489  37.173  1.00 27.78 ? 290 LEU   B CG   1 
ATOM   9082  C  CD1  . LEU   B 1 291 ? 5.917   17.350  37.540  1.00 32.90 ? 290 LEU   B CD1  1 
ATOM   9083  C  CD2  . LEU   B 1 291 ? 3.646   18.247  38.257  1.00 34.65 ? 290 LEU   B CD2  1 
ATOM   9084  H  H    . LEU   B 1 291 ? 3.861   18.468  33.167  1.00 31.85 ? 290 LEU   B H    1 
ATOM   9085  H  HA   . LEU   B 1 291 ? 5.833   17.421  34.714  1.00 34.08 ? 290 LEU   B HA   1 
ATOM   9086  H  HB2  . LEU   B 1 291 ? 4.669   19.083  35.946  1.00 41.59 ? 290 LEU   B HB2  1 
ATOM   9087  H  HB3  . LEU   B 1 291 ? 3.315   18.292  35.688  1.00 41.59 ? 290 LEU   B HB3  1 
ATOM   9088  H  HG   . LEU   B 1 291 ? 4.079   16.588  37.112  1.00 33.34 ? 290 LEU   B HG   1 
ATOM   9089  H  HD11 . LEU   B 1 291 ? 6.221   16.461  37.297  1.00 39.48 ? 290 LEU   B HD11 1 
ATOM   9090  H  HD12 . LEU   B 1 291 ? 6.426   18.018  37.054  1.00 39.48 ? 290 LEU   B HD12 1 
ATOM   9091  H  HD13 . LEU   B 1 291 ? 6.020   17.486  38.495  1.00 39.48 ? 290 LEU   B HD13 1 
ATOM   9092  H  HD21 . LEU   B 1 291 ? 3.691   17.747  39.088  1.00 41.58 ? 290 LEU   B HD21 1 
ATOM   9093  H  HD22 . LEU   B 1 291 ? 4.040   19.125  38.379  1.00 41.58 ? 290 LEU   B HD22 1 
ATOM   9094  H  HD23 . LEU   B 1 291 ? 2.723   18.335  37.974  1.00 41.58 ? 290 LEU   B HD23 1 
ATOM   9095  N  N    . THR   B 1 292 ? 5.094   15.138  34.601  1.00 24.64 ? 291 THR   B N    1 
ATOM   9096  C  CA   . THR   B 1 292 ? 4.597   13.774  34.709  1.00 24.85 ? 291 THR   B CA   1 
ATOM   9097  C  C    . THR   B 1 292 ? 5.144   13.084  35.954  1.00 33.11 ? 291 THR   B C    1 
ATOM   9098  O  O    . THR   B 1 292 ? 6.211   13.427  36.461  1.00 28.17 ? 291 THR   B O    1 
ATOM   9099  C  CB   . THR   B 1 292 ? 4.927   12.963  33.464  1.00 32.48 ? 291 THR   B CB   1 
ATOM   9100  O  OG1  . THR   B 1 292 ? 6.342   12.924  33.256  1.00 34.45 ? 291 THR   B OG1  1 
ATOM   9101  C  CG2  . THR   B 1 292 ? 4.270   13.607  32.274  1.00 40.43 ? 291 THR   B CG2  1 
ATOM   9102  H  H    . THR   B 1 292 ? 5.945   15.203  34.706  1.00 29.57 ? 291 THR   B H    1 
ATOM   9103  H  HA   . THR   B 1 292 ? 3.632   13.801  34.809  1.00 29.81 ? 291 THR   B HA   1 
ATOM   9104  H  HB   . THR   B 1 292 ? 4.606   12.053  33.567  1.00 38.97 ? 291 THR   B HB   1 
ATOM   9105  H  HG1  . THR   B 1 292 ? 6.616   13.677  33.005  1.00 41.34 ? 291 THR   B HG1  1 
ATOM   9106  H  HG21 . THR   B 1 292 ? 4.352   13.031  31.498  1.00 48.51 ? 291 THR   B HG21 1 
ATOM   9107  H  HG22 . THR   B 1 292 ? 3.329   13.758  32.456  1.00 48.51 ? 291 THR   B HG22 1 
ATOM   9108  H  HG23 . THR   B 1 292 ? 4.694   14.458  32.082  1.00 48.51 ? 291 THR   B HG23 1 
ATOM   9109  N  N    . LYS   B 1 293 ? 4.393   12.098  36.435  1.00 34.77 ? 292 LYS   B N    1 
ATOM   9110  C  CA   . LYS   B 1 293 ? 4.727   11.370  37.652  1.00 32.37 ? 292 LYS   B CA   1 
ATOM   9111  C  C    . LYS   B 1 293 ? 4.722   9.878   37.371  1.00 35.89 ? 292 LYS   B C    1 
ATOM   9112  O  O    . LYS   B 1 293 ? 3.975   9.387   36.517  1.00 34.15 ? 292 LYS   B O    1 
ATOM   9113  C  CB   . LYS   B 1 293 ? 3.761   11.769  38.780  1.00 40.05 ? 292 LYS   B CB   1 
ATOM   9114  C  CG   . LYS   B 1 293 ? 2.611   10.835  39.055  1.00 48.92 ? 292 LYS   B CG   1 
ATOM   9115  C  CD   . LYS   B 1 293 ? 2.093   11.068  40.486  1.00 48.47 ? 292 LYS   B CD   1 
ATOM   9116  C  CE   . LYS   B 1 293 ? 1.322   12.375  40.601  1.00 55.72 ? 292 LYS   B CE   1 
ATOM   9117  N  NZ   . LYS   B 1 293 ? -0.021  12.296  39.949  1.00 56.00 ? 292 LYS   B NZ   1 
ATOM   9118  H  H    . LYS   B 1 293 ? 3.667   11.826  36.064  1.00 41.72 ? 292 LYS   B H    1 
ATOM   9119  H  HA   . LYS   B 1 293 ? 5.626   11.572  37.956  1.00 38.85 ? 292 LYS   B HA   1 
ATOM   9120  H  HB2  . LYS   B 1 293 ? 4.271   11.838  39.602  1.00 48.06 ? 292 LYS   B HB2  1 
ATOM   9121  H  HB3  . LYS   B 1 293 ? 3.377   12.631  38.555  1.00 48.06 ? 292 LYS   B HB3  1 
ATOM   9122  H  HG2  . LYS   B 1 293 ? 1.891   11.007  38.428  1.00 58.70 ? 292 LYS   B HG2  1 
ATOM   9123  H  HG3  . LYS   B 1 293 ? 2.908   9.915   38.974  1.00 58.70 ? 292 LYS   B HG3  1 
ATOM   9124  H  HD2  . LYS   B 1 293 ? 1.499   10.342  40.734  1.00 58.16 ? 292 LYS   B HD2  1 
ATOM   9125  H  HD3  . LYS   B 1 293 ? 2.845   11.104  41.098  1.00 58.16 ? 292 LYS   B HD3  1 
ATOM   9126  H  HE2  . LYS   B 1 293 ? 1.191   12.586  41.539  1.00 66.86 ? 292 LYS   B HE2  1 
ATOM   9127  H  HE3  . LYS   B 1 293 ? 1.827   13.082  40.170  1.00 66.86 ? 292 LYS   B HE3  1 
ATOM   9128  H  HZ1  . LYS   B 1 293 ? 0.072   12.107  39.084  1.00 67.20 ? 292 LYS   B HZ1  1 
ATOM   9129  H  HZ2  . LYS   B 1 293 ? -0.509  11.660  40.333  1.00 67.20 ? 292 LYS   B HZ2  1 
ATOM   9130  H  HZ3  . LYS   B 1 293 ? -0.445  13.075  40.030  1.00 67.20 ? 292 LYS   B HZ3  1 
ATOM   9131  N  N    . SER   B 1 294 ? 5.582   9.159   38.090  1.00 27.98 ? 293 SER   B N    1 
ATOM   9132  C  CA   . SER   B 1 294 ? 5.678   7.717   37.932  1.00 32.23 ? 293 SER   B CA   1 
ATOM   9133  C  C    . SER   B 1 294 ? 6.303   7.099   39.166  1.00 36.93 ? 293 SER   B C    1 
ATOM   9134  O  O    . SER   B 1 294 ? 7.102   7.735   39.860  1.00 32.62 ? 293 SER   B O    1 
ATOM   9135  C  CB   . SER   B 1 294 ? 6.520   7.332   36.717  1.00 40.72 ? 293 SER   B CB   1 
ATOM   9136  O  OG   . SER   B 1 294 ? 7.877   7.699   36.931  1.00 44.19 ? 293 SER   B OG   1 
ATOM   9137  H  H    . SER   B 1 294 ? 6.119   9.486   38.676  1.00 33.57 ? 293 SER   B H    1 
ATOM   9138  H  HA   . SER   B 1 294 ? 4.778   7.372   37.828  1.00 38.67 ? 293 SER   B HA   1 
ATOM   9139  H  HB2  . SER   B 1 294 ? 6.466   6.373   36.583  1.00 48.87 ? 293 SER   B HB2  1 
ATOM   9140  H  HB3  . SER   B 1 294 ? 6.183   7.796   35.935  1.00 48.87 ? 293 SER   B HB3  1 
ATOM   9141  H  HG   . SER   B 1 294 ? 8.272   7.099   37.366  1.00 53.02 ? 293 SER   B HG   1 
ATOM   9142  N  N    . SER   B 1 295 ? 5.969   5.826   39.396  1.00 41.60 ? 294 SER   B N    1 
ATOM   9143  C  CA   . SER   B 1 295 ? 6.497   5.111   40.550  1.00 39.23 ? 294 SER   B CA   1 
ATOM   9144  C  C    . SER   B 1 295 ? 7.943   4.684   40.349  1.00 41.95 ? 294 SER   B C    1 
ATOM   9145  O  O    . SER   B 1 295 ? 8.714   4.643   41.315  1.00 37.94 ? 294 SER   B O    1 
ATOM   9146  C  CB   . SER   B 1 295 ? 5.649   3.862   40.819  1.00 40.82 ? 294 SER   B CB   1 
ATOM   9147  O  OG   . SER   B 1 295 ? 4.266   4.161   40.794  1.00 54.41 ? 294 SER   B OG   1 
ATOM   9148  H  H    . SER   B 1 295 ? 5.442   5.360   38.901  1.00 49.92 ? 294 SER   B H    1 
ATOM   9149  H  HA   . SER   B 1 295 ? 6.453   5.700   41.320  1.00 47.07 ? 294 SER   B HA   1 
ATOM   9150  H  HB2  . SER   B 1 295 ? 5.839   3.201   40.136  1.00 48.98 ? 294 SER   B HB2  1 
ATOM   9151  H  HB3  . SER   B 1 295 ? 5.877   3.510   41.694  1.00 48.98 ? 294 SER   B HB3  1 
ATOM   9152  H  HG   . SER   B 1 295 ? 3.973   4.101   40.009  1.00 65.29 ? 294 SER   B HG   1 
ATOM   9153  N  N    . GLU   B 1 296 ? 8.332   4.404   39.106  1.00 38.17 ? 295 GLU   B N    1 
ATOM   9154  C  CA   . GLU   B 1 296 ? 9.637   3.860   38.772  1.00 39.73 ? 295 GLU   B CA   1 
ATOM   9155  C  C    . GLU   B 1 296 ? 10.160  4.709   37.614  1.00 40.96 ? 295 GLU   B C    1 
ATOM   9156  O  O    . GLU   B 1 296 ? 9.411   5.494   37.020  1.00 35.08 ? 295 GLU   B O    1 
ATOM   9157  C  CB   . GLU   B 1 296 ? 9.466   2.360   38.470  1.00 45.78 ? 295 GLU   B CB   1 
ATOM   9158  C  CG   . GLU   B 1 296 ? 9.251   1.525   39.796  1.00 55.57 ? 295 GLU   B CG   1 
ATOM   9159  C  CD   . GLU   B 1 296 ? 10.495  0.965   40.437  1.00 64.39 ? 295 GLU   B CD   1 
ATOM   9160  O  OE1  . GLU   B 1 296 ? 11.332  0.378   39.715  1.00 65.46 ? 295 GLU   B OE1  1 
ATOM   9161  O  OE2  . GLU   B 1 296 ? 10.664  1.093   41.682  1.00 65.95 ? 295 GLU   B OE2  1 
ATOM   9162  H  H    . GLU   B 1 296 ? 7.834   4.526   38.415  1.00 45.80 ? 295 GLU   B H    1 
ATOM   9163  H  HA   . GLU   B 1 296 ? 10.312  3.915   39.467  1.00 47.68 ? 295 GLU   B HA   1 
ATOM   9164  H  HB2  . GLU   B 1 296 ? 8.692   2.233   37.899  1.00 54.94 ? 295 GLU   B HB2  1 
ATOM   9165  H  HB3  . GLU   B 1 296 ? 10.263  2.029   38.026  1.00 54.94 ? 295 GLU   B HB3  1 
ATOM   9166  H  HG2  . GLU   B 1 296 ? 8.827   2.102   40.451  1.00 66.68 ? 295 GLU   B HG2  1 
ATOM   9167  H  HG3  . GLU   B 1 296 ? 8.672   0.774   39.590  1.00 66.68 ? 295 GLU   B HG3  1 
ATOM   9168  N  N    . TYR   B 1 297 ? 11.458  4.621   37.350  1.00 37.15 ? 296 TYR   B N    1 
ATOM   9169  C  CA   . TYR   B 1 297 ? 12.059  5.419   36.287  1.00 33.83 ? 296 TYR   B CA   1 
ATOM   9170  C  C    . TYR   B 1 297 ? 13.251  4.655   35.731  1.00 35.20 ? 296 TYR   B C    1 
ATOM   9171  O  O    . TYR   B 1 297 ? 14.118  4.210   36.486  1.00 31.20 ? 296 TYR   B O    1 
ATOM   9172  C  CB   . TYR   B 1 297 ? 12.468  6.826   36.772  1.00 34.19 ? 296 TYR   B CB   1 
ATOM   9173  C  CG   . TYR   B 1 297 ? 13.161  7.607   35.665  1.00 34.84 ? 296 TYR   B CG   1 
ATOM   9174  C  CD1  . TYR   B 1 297 ? 14.482  7.353   35.368  1.00 29.33 ? 296 TYR   B CD1  1 
ATOM   9175  C  CD2  . TYR   B 1 297 ? 12.492  8.579   34.915  1.00 31.50 ? 296 TYR   B CD2  1 
ATOM   9176  C  CE1  . TYR   B 1 297 ? 15.142  8.025   34.333  1.00 30.20 ? 296 TYR   B CE1  1 
ATOM   9177  C  CE2  . TYR   B 1 297 ? 13.149  9.265   33.867  1.00 33.55 ? 296 TYR   B CE2  1 
ATOM   9178  C  CZ   . TYR   B 1 297 ? 14.473  8.972   33.591  1.00 29.52 ? 296 TYR   B CZ   1 
ATOM   9179  O  OH   . TYR   B 1 297 ? 15.178  9.609   32.576  1.00 31.37 ? 296 TYR   B OH   1 
ATOM   9180  H  H    . TYR   B 1 297 ? 12.009  4.111   37.769  1.00 44.58 ? 296 TYR   B H    1 
ATOM   9181  H  HA   . TYR   B 1 297 ? 11.416  5.546   35.572  1.00 40.60 ? 296 TYR   B HA   1 
ATOM   9182  H  HB2  . TYR   B 1 297 ? 11.675  7.316   37.043  1.00 41.03 ? 296 TYR   B HB2  1 
ATOM   9183  H  HB3  . TYR   B 1 297 ? 13.079  6.744   37.520  1.00 41.03 ? 296 TYR   B HB3  1 
ATOM   9184  H  HD1  . TYR   B 1 297 ? 14.946  6.719   35.866  1.00 35.19 ? 296 TYR   B HD1  1 
ATOM   9185  H  HD2  . TYR   B 1 297 ? 11.604  8.777   35.108  1.00 37.80 ? 296 TYR   B HD2  1 
ATOM   9186  H  HE1  . TYR   B 1 297 ? 16.032  7.833   34.148  1.00 36.24 ? 296 TYR   B HE1  1 
ATOM   9187  H  HE2  . TYR   B 1 297 ? 12.696  9.906   33.370  1.00 40.26 ? 296 TYR   B HE2  1 
ATOM   9188  H  HH   . TYR   B 1 297 ? 15.932  9.251   32.482  1.00 37.65 ? 296 TYR   B HH   1 
ATOM   9189  N  N    . LYS   B 1 298 ? 13.279  4.500   34.399  1.00 33.61 ? 297 LYS   B N    1 
ATOM   9190  C  CA   . LYS   B 1 298 ? 14.432  4.006   33.657  1.00 30.35 ? 297 LYS   B CA   1 
ATOM   9191  C  C    . LYS   B 1 298 ? 14.600  4.964   32.475  1.00 34.66 ? 297 LYS   B C    1 
ATOM   9192  O  O    . LYS   B 1 298 ? 13.631  5.230   31.756  1.00 31.49 ? 297 LYS   B O    1 
ATOM   9193  C  CB   . LYS   B 1 298 ? 14.219  2.556   33.195  1.00 32.66 ? 297 LYS   B CB   1 
ATOM   9194  C  CG   . LYS   B 1 298 ? 14.662  1.515   34.227  1.00 38.65 ? 297 LYS   B CG   1 
ATOM   9195  C  CD   . LYS   B 1 298 ? 14.726  0.068   33.721  1.00 45.41 ? 297 LYS   B CD   1 
ATOM   9196  C  CE   . LYS   B 1 298 ? 14.962  -0.871  34.926  1.00 45.76 ? 297 LYS   B CE   1 
ATOM   9197  N  NZ   . LYS   B 1 298 ? 15.123  -2.319  34.596  1.00 40.79 ? 297 LYS   B NZ   1 
ATOM   9198  H  H    . LYS   B 1 298 ? 12.612  4.684   33.889  1.00 40.33 ? 297 LYS   B H    1 
ATOM   9199  H  HA   . LYS   B 1 298 ? 15.241  4.000   34.192  1.00 36.42 ? 297 LYS   B HA   1 
ATOM   9200  H  HB2  . LYS   B 1 298 ? 13.275  2.419   33.020  1.00 39.20 ? 297 LYS   B HB2  1 
ATOM   9201  H  HB3  . LYS   B 1 298 ? 14.732  2.408   32.385  1.00 39.20 ? 297 LYS   B HB3  1 
ATOM   9202  H  HG2  . LYS   B 1 298 ? 15.551  1.750   34.538  1.00 46.38 ? 297 LYS   B HG2  1 
ATOM   9203  H  HG3  . LYS   B 1 298 ? 14.036  1.533   34.968  1.00 46.38 ? 297 LYS   B HG3  1 
ATOM   9204  H  HD2  . LYS   B 1 298 ? 13.890  -0.170  33.293  1.00 54.50 ? 297 LYS   B HD2  1 
ATOM   9205  H  HD3  . LYS   B 1 298 ? 15.460  -0.031  33.094  1.00 54.50 ? 297 LYS   B HD3  1 
ATOM   9206  H  HE2  . LYS   B 1 298 ? 15.771  -0.588  35.379  1.00 54.92 ? 297 LYS   B HE2  1 
ATOM   9207  H  HE3  . LYS   B 1 298 ? 14.202  -0.796  35.524  1.00 54.92 ? 297 LYS   B HE3  1 
ATOM   9208  H  HZ1  . LYS   B 1 298 ? 15.198  -2.795  35.345  1.00 48.95 ? 297 LYS   B HZ1  1 
ATOM   9209  H  HZ2  . LYS   B 1 298 ? 14.416  -2.608  34.140  1.00 48.95 ? 297 LYS   B HZ2  1 
ATOM   9210  H  HZ3  . LYS   B 1 298 ? 15.855  -2.439  34.103  1.00 48.95 ? 297 LYS   B HZ3  1 
ATOM   9211  N  N    . GLY   B 1 299 ? 15.795  5.547   32.325  1.00 27.17 ? 298 GLY   B N    1 
ATOM   9212  C  CA   . GLY   B 1 299 ? 16.061  6.532   31.292  1.00 25.67 ? 298 GLY   B CA   1 
ATOM   9213  C  C    . GLY   B 1 299 ? 17.499  7.024   31.283  1.00 23.88 ? 298 GLY   B C    1 
ATOM   9214  O  O    . GLY   B 1 299 ? 18.312  6.665   32.135  1.00 22.74 ? 298 GLY   B O    1 
ATOM   9215  H  H    . GLY   B 1 299 ? 16.476  5.380   32.822  1.00 32.60 ? 298 GLY   B H    1 
ATOM   9216  H  HA2  . GLY   B 1 299 ? 15.871  6.141   30.424  1.00 30.80 ? 298 GLY   B HA2  1 
ATOM   9217  H  HA3  . GLY   B 1 299 ? 15.481  7.298   31.427  1.00 30.80 ? 298 GLY   B HA3  1 
ATOM   9218  N  N    . PRO   B 1 300 ? 17.842  7.860   30.270  1.00 23.42 ? 299 PRO   B N    1 
ATOM   9219  C  CA   . PRO   B 1 300 ? 19.230  8.333   30.094  1.00 19.41 ? 299 PRO   B CA   1 
ATOM   9220  C  C    . PRO   B 1 300 ? 19.539  9.491   31.039  1.00 19.71 ? 299 PRO   B C    1 
ATOM   9221  O  O    . PRO   B 1 300 ? 19.065  10.614  30.874  1.00 20.12 ? 299 PRO   B O    1 
ATOM   9222  C  CB   . PRO   B 1 300 ? 19.253  8.759   28.607  1.00 19.32 ? 299 PRO   B CB   1 
ATOM   9223  C  CG   . PRO   B 1 300 ? 17.855  9.217   28.366  1.00 23.22 ? 299 PRO   B CG   1 
ATOM   9224  C  CD   . PRO   B 1 300 ? 16.932  8.392   29.250  1.00 25.34 ? 299 PRO   B CD   1 
ATOM   9225  H  HA   . PRO   B 1 300 ? 19.868  7.618   30.243  1.00 23.29 ? 299 PRO   B HA   1 
ATOM   9226  H  HB2  . PRO   B 1 300 ? 19.890  9.479   28.472  1.00 23.18 ? 299 PRO   B HB2  1 
ATOM   9227  H  HB3  . PRO   B 1 300 ? 19.481  8.004   28.043  1.00 23.18 ? 299 PRO   B HB3  1 
ATOM   9228  H  HG2  . PRO   B 1 300 ? 17.784  10.158  28.592  1.00 27.87 ? 299 PRO   B HG2  1 
ATOM   9229  H  HG3  . PRO   B 1 300 ? 17.633  9.083   27.431  1.00 27.87 ? 299 PRO   B HG3  1 
ATOM   9230  H  HD2  . PRO   B 1 300 ? 16.249  8.950   29.653  1.00 30.41 ? 299 PRO   B HD2  1 
ATOM   9231  H  HD3  . PRO   B 1 300 ? 16.520  7.674   28.745  1.00 30.41 ? 299 PRO   B HD3  1 
ATOM   9232  N  N    . ILE   B 1 301 ? 20.336  9.188   32.060  1.00 18.85 ? 300 ILE   B N    1 
ATOM   9233  C  CA   . ILE   B 1 301 ? 20.673  10.133  33.122  1.00 14.30 ? 300 ILE   B CA   1 
ATOM   9234  C  C    . ILE   B 1 301 ? 22.137  10.515  32.976  1.00 14.35 ? 300 ILE   B C    1 
ATOM   9235  O  O    . ILE   B 1 301 ? 22.981  9.678   32.625  1.00 19.96 ? 300 ILE   B O    1 
ATOM   9236  C  CB   . ILE   B 1 301 ? 20.381  9.487   34.495  1.00 16.03 ? 300 ILE   B CB   1 
ATOM   9237  C  CG1  . ILE   B 1 301 ? 18.891  9.164   34.640  1.00 17.40 ? 300 ILE   B CG1  1 
ATOM   9238  C  CG2  . ILE   B 1 301 ? 20.813  10.403  35.606  1.00 18.31 ? 300 ILE   B CG2  1 
ATOM   9239  C  CD1  . ILE   B 1 301 ? 17.984  10.330  34.484  1.00 20.54 ? 300 ILE   B CD1  1 
ATOM   9240  H  H    . ILE   B 1 301 ? 20.705  8.418   32.163  1.00 22.62 ? 300 ILE   B H    1 
ATOM   9241  H  HA   . ILE   B 1 301 ? 20.154  10.949  33.041  1.00 17.16 ? 300 ILE   B HA   1 
ATOM   9242  H  HB   . ILE   B 1 301 ? 20.885  8.660   34.548  1.00 19.24 ? 300 ILE   B HB   1 
ATOM   9243  H  HG12 . ILE   B 1 301 ? 18.650  8.514   33.962  1.00 20.88 ? 300 ILE   B HG12 1 
ATOM   9244  H  HG13 . ILE   B 1 301 ? 18.741  8.793   35.524  1.00 20.88 ? 300 ILE   B HG13 1 
ATOM   9245  H  HG21 . ILE   B 1 301 ? 20.333  10.166  36.416  1.00 21.98 ? 300 ILE   B HG21 1 
ATOM   9246  H  HG22 . ILE   B 1 301 ? 21.767  10.303  35.746  1.00 21.98 ? 300 ILE   B HG22 1 
ATOM   9247  H  HG23 . ILE   B 1 301 ? 20.609  11.319  35.358  1.00 21.98 ? 300 ILE   B HG23 1 
ATOM   9248  H  HD11 . ILE   B 1 301 ? 17.130  10.122  34.894  1.00 24.64 ? 300 ILE   B HD11 1 
ATOM   9249  H  HD12 . ILE   B 1 301 ? 18.382  11.100  34.920  1.00 24.64 ? 300 ILE   B HD12 1 
ATOM   9250  H  HD13 . ILE   B 1 301 ? 17.862  10.511  33.539  1.00 24.64 ? 300 ILE   B HD13 1 
ATOM   9251  N  N    . THR   B 1 302 ? 22.457  11.789  33.284  1.00 16.70 ? 301 THR   B N    1 
ATOM   9252  C  CA   . THR   B 1 302 ? 23.831  12.272  33.228  1.00 17.94 ? 301 THR   B CA   1 
ATOM   9253  C  C    . THR   B 1 302 ? 24.316  12.981  34.508  1.00 15.76 ? 301 THR   B C    1 
ATOM   9254  O  O    . THR   B 1 302 ? 25.548  13.060  34.714  1.00 17.56 ? 301 THR   B O    1 
ATOM   9255  C  CB   . THR   B 1 302 ? 24.020  13.187  31.982  1.00 17.52 ? 301 THR   B CB   1 
ATOM   9256  O  OG1  . THR   B 1 302 ? 25.412  13.467  31.779  1.00 20.08 ? 301 THR   B OG1  1 
ATOM   9257  C  CG2  . THR   B 1 302 ? 23.243  14.477  32.101  1.00 21.11 ? 301 THR   B CG2  1 
ATOM   9258  H  H    . THR   B 1 302 ? 21.887  12.385  33.527  1.00 20.04 ? 301 THR   B H    1 
ATOM   9259  H  HA   . THR   B 1 302 ? 24.431  11.518  33.111  1.00 21.52 ? 301 THR   B HA   1 
ATOM   9260  H  HB   . THR   B 1 302 ? 23.673  12.719  31.206  1.00 21.03 ? 301 THR   B HB   1 
ATOM   9261  H  HG1  . THR   B 1 302 ? 25.780  12.824  31.384  1.00 24.10 ? 301 THR   B HG1  1 
ATOM   9262  H  HG21 . THR   B 1 302 ? 23.083  14.851  31.220  1.00 25.34 ? 301 THR   B HG21 1 
ATOM   9263  H  HG22 . THR   B 1 302 ? 22.391  14.313  32.533  1.00 25.34 ? 301 THR   B HG22 1 
ATOM   9264  H  HG23 . THR   B 1 302 ? 23.745  15.119  32.628  1.00 25.34 ? 301 THR   B HG23 1 
ATOM   9265  N  N    . ASP   B 1 303 ? 23.413  13.416  35.399  1.00 19.45 ? 302 ASP   B N    1 
ATOM   9266  C  CA   . ASP   B 1 303 ? 23.760  13.929  36.736  1.00 16.80 ? 302 ASP   B CA   1 
ATOM   9267  C  C    . ASP   B 1 303 ? 22.760  13.387  37.743  1.00 17.76 ? 302 ASP   B C    1 
ATOM   9268  O  O    . ASP   B 1 303 ? 21.554  13.385  37.483  1.00 17.43 ? 302 ASP   B O    1 
ATOM   9269  C  CB   . ASP   B 1 303 ? 23.707  15.481  36.822  1.00 18.55 ? 302 ASP   B CB   1 
ATOM   9270  C  CG   . ASP   B 1 303 ? 24.415  16.170  35.645  1.00 20.87 ? 302 ASP   B CG   1 
ATOM   9271  O  OD1  . ASP   B 1 303 ? 25.651  16.007  35.488  1.00 20.48 ? 302 ASP   B OD1  1 
ATOM   9272  O  OD2  . ASP   B 1 303 ? 23.744  16.927  34.909  1.00 19.42 ? 302 ASP   B OD2  1 
ATOM   9273  H  H    . ASP   B 1 303 ? 22.566  13.425  35.249  1.00 23.34 ? 302 ASP   B H    1 
ATOM   9274  H  HA   . ASP   B 1 303 ? 24.660  13.634  36.947  1.00 20.15 ? 302 ASP   B HA   1 
ATOM   9275  H  HB2  . ASP   B 1 303 ? 22.780  15.765  36.822  1.00 22.26 ? 302 ASP   B HB2  1 
ATOM   9276  H  HB3  . ASP   B 1 303 ? 24.141  15.766  37.641  1.00 22.26 ? 302 ASP   B HB3  1 
ATOM   9277  N  N    . VAL   B 1 304 ? 23.247  13.015  38.927  1.00 19.89 ? 303 VAL   B N    1 
ATOM   9278  C  CA   . VAL   B 1 304 ? 22.387  12.729  40.067  1.00 18.07 ? 303 VAL   B CA   1 
ATOM   9279  C  C    . VAL   B 1 304 ? 22.911  13.505  41.268  1.00 16.06 ? 303 VAL   B C    1 
ATOM   9280  O  O    . VAL   B 1 304 ? 24.128  13.527  41.519  1.00 16.83 ? 303 VAL   B O    1 
ATOM   9281  C  CB   . VAL   B 1 304 ? 22.318  11.228  40.388  1.00 16.78 ? 303 VAL   B CB   1 
ATOM   9282  C  CG1  . VAL   B 1 304 ? 21.307  10.986  41.491  1.00 16.06 ? 303 VAL   B CG1  1 
ATOM   9283  C  CG2  . VAL   B 1 304 ? 21.918  10.421  39.133  1.00 22.34 ? 303 VAL   B CG2  1 
ATOM   9284  H  H    . VAL   B 1 304 ? 24.085  12.920  39.094  1.00 23.87 ? 303 VAL   B H    1 
ATOM   9285  H  HA   . VAL   B 1 304 ? 21.488  13.033  39.866  1.00 21.68 ? 303 VAL   B HA   1 
ATOM   9286  H  HB   . VAL   B 1 304 ? 23.192  10.929  40.682  1.00 20.13 ? 303 VAL   B HB   1 
ATOM   9287  H  HG11 . VAL   B 1 304 ? 21.155  10.032  41.576  1.00 19.27 ? 303 VAL   B HG11 1 
ATOM   9288  H  HG12 . VAL   B 1 304 ? 21.657  11.341  42.323  1.00 19.27 ? 303 VAL   B HG12 1 
ATOM   9289  H  HG13 . VAL   B 1 304 ? 20.478  11.435  41.263  1.00 19.27 ? 303 VAL   B HG13 1 
ATOM   9290  H  HG21 . VAL   B 1 304 ? 21.695  9.515   39.399  1.00 26.80 ? 303 VAL   B HG21 1 
ATOM   9291  H  HG22 . VAL   B 1 304 ? 21.149  10.843  38.718  1.00 26.80 ? 303 VAL   B HG22 1 
ATOM   9292  H  HG23 . VAL   B 1 304 ? 22.664  10.410  38.514  1.00 26.80 ? 303 VAL   B HG23 1 
ATOM   9293  N  N    . PHE   B 1 305 ? 21.996  14.148  41.973  1.00 18.57 ? 304 PHE   B N    1 
ATOM   9294  C  CA   . PHE   B 1 305 ? 22.302  14.897  43.183  1.00 15.97 ? 304 PHE   B CA   1 
ATOM   9295  C  C    . PHE   B 1 305 ? 21.778  14.157  44.411  1.00 18.80 ? 304 PHE   B C    1 
ATOM   9296  O  O    . PHE   B 1 305 ? 20.647  13.648  44.435  1.00 17.77 ? 304 PHE   B O    1 
ATOM   9297  C  CB   . PHE   B 1 305 ? 21.709  16.291  43.119  1.00 18.67 ? 304 PHE   B CB   1 
ATOM   9298  C  CG   . PHE   B 1 305 ? 22.234  17.111  41.979  1.00 18.55 ? 304 PHE   B CG   1 
ATOM   9299  C  CD1  . PHE   B 1 305 ? 21.713  16.947  40.710  1.00 19.30 ? 304 PHE   B CD1  1 
ATOM   9300  C  CD2  . PHE   B 1 305 ? 23.272  18.021  42.164  1.00 24.97 ? 304 PHE   B CD2  1 
ATOM   9301  C  CE1  . PHE   B 1 305 ? 22.195  17.724  39.624  1.00 18.28 ? 304 PHE   B CE1  1 
ATOM   9302  C  CE2  . PHE   B 1 305 ? 23.750  18.797  41.068  1.00 21.77 ? 304 PHE   B CE2  1 
ATOM   9303  C  CZ   . PHE   B 1 305 ? 23.221  18.623  39.822  1.00 23.01 ? 304 PHE   B CZ   1 
ATOM   9304  H  H    . PHE   B 1 305 ? 21.162  14.167  41.764  1.00 22.28 ? 304 PHE   B H    1 
ATOM   9305  H  HA   . PHE   B 1 305 ? 23.264  14.979  43.278  1.00 19.16 ? 304 PHE   B HA   1 
ATOM   9306  H  HB2  . PHE   B 1 305 ? 20.747  16.218  43.014  1.00 22.41 ? 304 PHE   B HB2  1 
ATOM   9307  H  HB3  . PHE   B 1 305 ? 21.918  16.759  43.942  1.00 22.41 ? 304 PHE   B HB3  1 
ATOM   9308  H  HD1  . PHE   B 1 305 ? 21.040  16.322  40.565  1.00 23.16 ? 304 PHE   B HD1  1 
ATOM   9309  H  HD2  . PHE   B 1 305 ? 23.654  18.122  43.005  1.00 29.97 ? 304 PHE   B HD2  1 
ATOM   9310  H  HE1  . PHE   B 1 305 ? 21.818  17.627  38.779  1.00 21.93 ? 304 PHE   B HE1  1 
ATOM   9311  H  HE2  . PHE   B 1 305 ? 24.425  19.423  41.202  1.00 26.13 ? 304 PHE   B HE2  1 
ATOM   9312  H  HZ   . PHE   B 1 305 ? 23.554  19.113  39.105  1.00 27.61 ? 304 PHE   B HZ   1 
ATOM   9313  N  N    . TYR   B 1 306 ? 22.602  14.152  45.447  1.00 19.19 ? 305 TYR   B N    1 
ATOM   9314  C  CA   . TYR   B 1 306 ? 22.279  13.511  46.701  1.00 16.61 ? 305 TYR   B CA   1 
ATOM   9315  C  C    . TYR   B 1 306 ? 22.584  14.474  47.823  1.00 18.03 ? 305 TYR   B C    1 
ATOM   9316  O  O    . TYR   B 1 306 ? 23.675  15.051  47.865  1.00 19.30 ? 305 TYR   B O    1 
ATOM   9317  C  CB   . TYR   B 1 306 ? 23.104  12.262  46.917  1.00 18.47 ? 305 TYR   B CB   1 
ATOM   9318  C  CG   . TYR   B 1 306 ? 23.086  11.250  45.798  1.00 17.67 ? 305 TYR   B CG   1 
ATOM   9319  C  CD1  . TYR   B 1 306 ? 23.912  11.409  44.695  1.00 18.58 ? 305 TYR   B CD1  1 
ATOM   9320  C  CD2  . TYR   B 1 306 ? 22.255  10.135  45.854  1.00 18.17 ? 305 TYR   B CD2  1 
ATOM   9321  C  CE1  . TYR   B 1 306 ? 23.928  10.456  43.680  1.00 16.56 ? 305 TYR   B CE1  1 
ATOM   9322  C  CE2  . TYR   B 1 306 ? 22.263  9.169   44.862  1.00 19.62 ? 305 TYR   B CE2  1 
ATOM   9323  C  CZ   . TYR   B 1 306 ? 23.102  9.336   43.772  1.00 17.36 ? 305 TYR   B CZ   1 
ATOM   9324  O  OH   . TYR   B 1 306 ? 23.122  8.403   42.762  1.00 20.11 ? 305 TYR   B OH   1 
ATOM   9325  H  H    . TYR   B 1 306 ? 23.377  14.525  45.443  1.00 23.03 ? 305 TYR   B H    1 
ATOM   9326  H  HA   . TYR   B 1 306 ? 21.337  13.278  46.702  1.00 19.93 ? 305 TYR   B HA   1 
ATOM   9327  H  HB2  . TYR   B 1 306 ? 24.027  12.529  47.047  1.00 22.16 ? 305 TYR   B HB2  1 
ATOM   9328  H  HB3  . TYR   B 1 306 ? 22.773  11.815  47.712  1.00 22.16 ? 305 TYR   B HB3  1 
ATOM   9329  H  HD1  . TYR   B 1 306 ? 24.459  12.159  44.633  1.00 22.30 ? 305 TYR   B HD1  1 
ATOM   9330  H  HD2  . TYR   B 1 306 ? 21.679  10.036  46.578  1.00 21.81 ? 305 TYR   B HD2  1 
ATOM   9331  H  HE1  . TYR   B 1 306 ? 24.486  10.566  42.944  1.00 19.87 ? 305 TYR   B HE1  1 
ATOM   9332  H  HE2  . TYR   B 1 306 ? 21.715  8.421   44.927  1.00 23.54 ? 305 TYR   B HE2  1 
ATOM   9333  H  HH   . TYR   B 1 306 ? 23.410  8.752   42.054  1.00 24.13 ? 305 TYR   B HH   1 
ATOM   9334  N  N    . LYS   B 1 307 ? 21.644  14.624  48.736  1.00 18.18 ? 306 LYS   B N    1 
ATOM   9335  C  CA   . LYS   B 1 307 ? 21.931  15.387  49.945  1.00 20.19 ? 306 LYS   B CA   1 
ATOM   9336  C  C    . LYS   B 1 307 ? 22.910  14.626  50.841  1.00 19.97 ? 306 LYS   B C    1 
ATOM   9337  O  O    . LYS   B 1 307 ? 23.055  13.403  50.756  1.00 19.84 ? 306 LYS   B O    1 
ATOM   9338  C  CB   . LYS   B 1 307 ? 20.643  15.661  50.698  1.00 21.20 ? 306 LYS   B CB   1 
ATOM   9339  C  CG   . LYS   B 1 307 ? 19.607  16.389  49.907  1.00 35.01 ? 306 LYS   B CG   1 
ATOM   9340  C  CD   . LYS   B 1 307 ? 19.238  17.729  50.485  1.00 44.43 ? 306 LYS   B CD   1 
ATOM   9341  C  CE   . LYS   B 1 307 ? 17.834  18.093  50.028  1.00 40.29 ? 306 LYS   B CE   1 
ATOM   9342  N  NZ   . LYS   B 1 307 ? 17.322  19.347  50.620  1.00 37.65 ? 306 LYS   B NZ   1 
ATOM   9343  H  H    . LYS   B 1 307 ? 20.847  14.303  48.686  1.00 21.82 ? 306 LYS   B H    1 
ATOM   9344  H  HA   . LYS   B 1 307 ? 22.337  16.237  49.711  1.00 24.22 ? 306 LYS   B HA   1 
ATOM   9345  H  HB2  . LYS   B 1 307 ? 20.260  14.813  50.973  1.00 25.44 ? 306 LYS   B HB2  1 
ATOM   9346  H  HB3  . LYS   B 1 307 ? 20.850  16.200  51.478  1.00 25.44 ? 306 LYS   B HB3  1 
ATOM   9347  H  HG2  . LYS   B 1 307 ? 19.944  16.537  49.010  1.00 42.01 ? 306 LYS   B HG2  1 
ATOM   9348  H  HG3  . LYS   B 1 307 ? 18.802  15.849  49.874  1.00 42.01 ? 306 LYS   B HG3  1 
ATOM   9349  H  HD2  . LYS   B 1 307 ? 19.253  17.687  51.454  1.00 53.31 ? 306 LYS   B HD2  1 
ATOM   9350  H  HD3  . LYS   B 1 307 ? 19.857  18.406  50.172  1.00 53.31 ? 306 LYS   B HD3  1 
ATOM   9351  H  HE2  . LYS   B 1 307 ? 17.838  18.201  49.064  1.00 48.35 ? 306 LYS   B HE2  1 
ATOM   9352  H  HE3  . LYS   B 1 307 ? 17.228  17.378  50.280  1.00 48.35 ? 306 LYS   B HE3  1 
ATOM   9353  H  HZ1  . LYS   B 1 307 ? 16.656  19.668  50.124  1.00 45.18 ? 306 LYS   B HZ1  1 
ATOM   9354  H  HZ2  . LYS   B 1 307 ? 17.021  19.194  51.443  1.00 45.18 ? 306 LYS   B HZ2  1 
ATOM   9355  H  HZ3  . LYS   B 1 307 ? 17.972  19.953  50.658  1.00 45.18 ? 306 LYS   B HZ3  1 
ATOM   9356  N  N    . GLU   B 1 308 ? 23.637  15.381  51.659  1.00 20.66 ? 307 GLU   B N    1 
ATOM   9357  C  CA   . GLU   B 1 308 ? 24.666  14.816  52.529  1.00 20.25 ? 307 GLU   B CA   1 
ATOM   9358  C  C    . GLU   B 1 308 ? 24.812  15.738  53.729  1.00 16.17 ? 307 GLU   B C    1 
ATOM   9359  O  O    . GLU   B 1 308 ? 24.310  16.873  53.732  1.00 17.23 ? 307 GLU   B O    1 
ATOM   9360  C  CB   . GLU   B 1 308 ? 25.988  14.659  51.774  1.00 20.22 ? 307 GLU   B CB   1 
ATOM   9361  C  CG   . GLU   B 1 308 ? 27.099  13.945  52.541  1.00 23.63 ? 307 GLU   B CG   1 
ATOM   9362  C  CD   . GLU   B 1 308 ? 26.660  12.635  53.175  1.00 22.14 ? 307 GLU   B CD   1 
ATOM   9363  O  OE1  . GLU   B 1 308 ? 26.729  11.606  52.484  1.00 24.70 ? 307 GLU   B OE1  1 
ATOM   9364  O  OE2  . GLU   B 1 308 ? 26.256  12.642  54.386  1.00 20.30 ? 307 GLU   B OE2  1 
ATOM   9365  H  H    . GLU   B 1 308 ? 23.554  16.234  51.729  1.00 24.79 ? 307 GLU   B H    1 
ATOM   9366  H  HA   . GLU   B 1 308 ? 24.400  13.939  52.849  1.00 24.30 ? 307 GLU   B HA   1 
ATOM   9367  H  HB2  . GLU   B 1 308 ? 25.820  14.150  50.966  1.00 24.26 ? 307 GLU   B HB2  1 
ATOM   9368  H  HB3  . GLU   B 1 308 ? 26.316  15.543  51.547  1.00 24.26 ? 307 GLU   B HB3  1 
ATOM   9369  H  HG2  . GLU   B 1 308 ? 27.824  13.748  51.928  1.00 28.35 ? 307 GLU   B HG2  1 
ATOM   9370  H  HG3  . GLU   B 1 308 ? 27.412  14.527  53.250  1.00 28.35 ? 307 GLU   B HG3  1 
ATOM   9371  N  N    . ASN   B 1 309 ? 25.500  15.238  54.753  1.00 19.50 ? 308 ASN   B N    1 
ATOM   9372  C  CA   . ASN   B 1 309 ? 26.059  16.134  55.751  1.00 19.86 ? 308 ASN   B CA   1 
ATOM   9373  C  C    . ASN   B 1 309 ? 27.446  15.650  56.132  1.00 21.48 ? 308 ASN   B C    1 
ATOM   9374  O  O    . ASN   B 1 309 ? 28.436  16.325  55.843  1.00 19.26 ? 308 ASN   B O    1 
ATOM   9375  C  CB   . ASN   B 1 309 ? 25.176  16.253  56.982  1.00 22.69 ? 308 ASN   B CB   1 
ATOM   9376  C  CG   . ASN   B 1 309 ? 25.700  17.329  57.931  1.00 29.82 ? 308 ASN   B CG   1 
ATOM   9377  O  OD1  . ASN   B 1 309 ? 26.506  17.032  58.801  1.00 30.58 ? 308 ASN   B OD1  1 
ATOM   9378  N  ND2  . ASN   B 1 309 ? 25.342  18.590  57.683  1.00 33.64 ? 308 ASN   B ND2  1 
ATOM   9379  H  H    . ASN   B 1 309 ? 25.651  14.402  54.886  1.00 23.39 ? 308 ASN   B H    1 
ATOM   9380  H  HA   . ASN   B 1 309 ? 26.115  17.026  55.376  1.00 23.83 ? 308 ASN   B HA   1 
ATOM   9381  H  HB2  . ASN   B 1 309 ? 24.276  16.493  56.712  1.00 27.23 ? 308 ASN   B HB2  1 
ATOM   9382  H  HB3  . ASN   B 1 309 ? 25.166  15.405  57.455  1.00 27.23 ? 308 ASN   B HB3  1 
ATOM   9383  H  HD21 . ASN   B 1 309 ? 24.836  18.769  57.011  1.00 40.37 ? 308 ASN   B HD21 1 
ATOM   9384  H  HD22 . ASN   B 1 309 ? 25.617  19.224  58.195  1.00 40.37 ? 308 ASN   B HD22 1 
ATOM   9385  N  N    . SER   B 1 310 ? 27.528  14.470  56.740  1.00 20.19 ? 309 SER   B N    1 
ATOM   9386  C  CA   . SER   B 1 310 ? 28.811  13.868  57.072  1.00 18.56 ? 309 SER   B CA   1 
ATOM   9387  C  C    . SER   B 1 310 ? 28.720  12.363  56.877  1.00 23.31 ? 309 SER   B C    1 
ATOM   9388  O  O    . SER   B 1 310 ? 27.877  11.688  57.489  1.00 23.10 ? 309 SER   B O    1 
ATOM   9389  C  CB   . SER   B 1 310 ? 29.212  14.230  58.507  1.00 25.17 ? 309 SER   B CB   1 
ATOM   9390  O  OG   . SER   B 1 310 ? 30.466  13.654  58.818  1.00 26.22 ? 309 SER   B OG   1 
ATOM   9391  H  H    . SER   B 1 310 ? 26.848  13.997  56.971  1.00 24.22 ? 309 SER   B H    1 
ATOM   9392  H  HA   . SER   B 1 310 ? 29.499  14.191  56.469  1.00 22.27 ? 309 SER   B HA   1 
ATOM   9393  H  HB2  . SER   B 1 310 ? 29.274  15.194  58.588  1.00 30.21 ? 309 SER   B HB2  1 
ATOM   9394  H  HB3  . SER   B 1 310 ? 28.542  13.888  59.121  1.00 30.21 ? 309 SER   B HB3  1 
ATOM   9395  H  HG   . SER   B 1 310 ? 30.924  13.569  58.120  1.00 31.46 ? 309 SER   B HG   1 
ATOM   9396  N  N    . TYR   B 1 311 ? 29.578  11.832  56.013  1.00 21.96 ? 310 TYR   B N    1 
ATOM   9397  C  CA   . TYR   B 1 311 ? 29.655  10.409  55.764  1.00 20.76 ? 310 TYR   B CA   1 
ATOM   9398  C  C    . TYR   B 1 311 ? 31.049  9.904   56.104  1.00 26.97 ? 310 TYR   B C    1 
ATOM   9399  O  O    . TYR   B 1 311 ? 32.054  10.522  55.734  1.00 20.69 ? 310 TYR   B O    1 
ATOM   9400  C  CB   . TYR   B 1 311 ? 29.348  10.067  54.306  1.00 19.48 ? 310 TYR   B CB   1 
ATOM   9401  C  CG   . TYR   B 1 311 ? 29.700  8.636   53.946  1.00 20.51 ? 310 TYR   B CG   1 
ATOM   9402  C  CD1  . TYR   B 1 311 ? 28.841  7.587   54.277  1.00 23.06 ? 310 TYR   B CD1  1 
ATOM   9403  C  CD2  . TYR   B 1 311 ? 30.892  8.324   53.285  1.00 21.75 ? 310 TYR   B CD2  1 
ATOM   9404  C  CE1  . TYR   B 1 311 ? 29.140  6.285   53.955  1.00 24.30 ? 310 TYR   B CE1  1 
ATOM   9405  C  CE2  . TYR   B 1 311 ? 31.207  6.996   52.973  1.00 22.78 ? 310 TYR   B CE2  1 
ATOM   9406  C  CZ   . TYR   B 1 311 ? 30.321  5.983   53.317  1.00 23.19 ? 310 TYR   B CZ   1 
ATOM   9407  O  OH   . TYR   B 1 311 ? 30.610  4.665   53.009  1.00 28.07 ? 310 TYR   B OH   1 
ATOM   9408  H  H    . TYR   B 1 311 ? 30.137  12.293  55.550  1.00 26.35 ? 310 TYR   B H    1 
ATOM   9409  H  HA   . TYR   B 1 311 ? 29.006  9.961   56.328  1.00 24.91 ? 310 TYR   B HA   1 
ATOM   9410  H  HB2  . TYR   B 1 311 ? 28.399  10.191  54.147  1.00 23.37 ? 310 TYR   B HB2  1 
ATOM   9411  H  HB3  . TYR   B 1 311 ? 29.860  10.656  53.730  1.00 23.37 ? 310 TYR   B HB3  1 
ATOM   9412  H  HD1  . TYR   B 1 311 ? 28.047  7.774   54.725  1.00 27.68 ? 310 TYR   B HD1  1 
ATOM   9413  H  HD2  . TYR   B 1 311 ? 31.480  9.005   53.051  1.00 26.10 ? 310 TYR   B HD2  1 
ATOM   9414  H  HE1  . TYR   B 1 311 ? 28.542  5.605   54.169  1.00 29.16 ? 310 TYR   B HE1  1 
ATOM   9415  H  HE2  . TYR   B 1 311 ? 32.004  6.794   52.538  1.00 27.34 ? 310 TYR   B HE2  1 
ATOM   9416  H  HH   . TYR   B 1 311 ? 30.884  4.608   52.217  1.00 33.68 ? 310 TYR   B HH   1 
ATOM   9417  N  N    . THR   B 1 312 ? 31.102  8.761   56.797  1.00 21.84 ? 311 THR   B N    1 
ATOM   9418  C  CA   . THR   B 1 312 ? 32.359  8.088   57.086  1.00 23.77 ? 311 THR   B CA   1 
ATOM   9419  C  C    . THR   B 1 312 ? 32.193  6.614   56.751  1.00 28.19 ? 311 THR   B C    1 
ATOM   9420  O  O    . THR   B 1 312 ? 31.221  5.991   57.182  1.00 30.59 ? 311 THR   B O    1 
ATOM   9421  C  CB   . THR   B 1 312 ? 32.760  8.245   58.563  1.00 26.99 ? 311 THR   B CB   1 
ATOM   9422  O  OG1  . THR   B 1 312 ? 32.992  9.621   58.854  1.00 29.72 ? 311 THR   B OG1  1 
ATOM   9423  C  CG2  . THR   B 1 312 ? 34.054  7.470   58.789  1.00 29.95 ? 311 THR   B CG2  1 
ATOM   9424  H  H    . THR   B 1 312 ? 30.411  8.356   57.111  1.00 26.21 ? 311 THR   B H    1 
ATOM   9425  H  HA   . THR   B 1 312 ? 33.067  8.467   56.542  1.00 28.53 ? 311 THR   B HA   1 
ATOM   9426  H  HB   . THR   B 1 312 ? 32.060  7.912   59.146  1.00 32.39 ? 311 THR   B HB   1 
ATOM   9427  H  HG1  . THR   B 1 312 ? 33.281  10.014  58.171  1.00 35.66 ? 311 THR   B HG1  1 
ATOM   9428  H  HG21 . THR   B 1 312 ? 34.516  7.815   59.569  1.00 35.94 ? 311 THR   B HG21 1 
ATOM   9429  H  HG22 . THR   B 1 312 ? 33.858  6.530   58.930  1.00 35.94 ? 311 THR   B HG22 1 
ATOM   9430  H  HG23 . THR   B 1 312 ? 34.633  7.558   58.016  1.00 35.94 ? 311 THR   B HG23 1 
ATOM   9431  N  N    . THR   B 1 313 ? 33.123  6.060   55.985  1.00 23.01 ? 312 THR   B N    1 
ATOM   9432  C  CA   . THR   B 1 313 ? 33.029  4.678   55.525  1.00 25.07 ? 312 THR   B CA   1 
ATOM   9433  C  C    . THR   B 1 313 ? 33.134  3.701   56.691  1.00 36.52 ? 312 THR   B C    1 
ATOM   9434  O  O    . THR   B 1 313 ? 33.696  4.008   57.744  1.00 27.25 ? 312 THR   B O    1 
ATOM   9435  C  CB   . THR   B 1 313 ? 34.149  4.369   54.526  1.00 29.24 ? 312 THR   B CB   1 
ATOM   9436  O  OG1  . THR   B 1 313 ? 33.939  3.099   53.881  1.00 32.54 ? 312 THR   B OG1  1 
ATOM   9437  C  CG2  . THR   B 1 313 ? 35.491  4.345   55.242  1.00 28.40 ? 312 THR   B CG2  1 
ATOM   9438  H  H    . THR   B 1 313 ? 33.830  6.467   55.712  1.00 27.62 ? 312 THR   B H    1 
ATOM   9439  H  HA   . THR   B 1 313 ? 32.170  4.556   55.092  1.00 30.09 ? 312 THR   B HA   1 
ATOM   9440  H  HB   . THR   B 1 313 ? 34.155  5.059   53.845  1.00 35.09 ? 312 THR   B HB   1 
ATOM   9441  H  HG1  . THR   B 1 313 ? 33.143  3.039   53.617  1.00 39.05 ? 312 THR   B HG1  1 
ATOM   9442  H  HG21 . THR   B 1 313 ? 36.202  4.572   54.623  1.00 34.08 ? 312 THR   B HG21 1 
ATOM   9443  H  HG22 . THR   B 1 313 ? 35.490  4.987   55.970  1.00 34.08 ? 312 THR   B HG22 1 
ATOM   9444  H  HG23 . THR   B 1 313 ? 35.658  3.460   55.603  1.00 34.08 ? 312 THR   B HG23 1 
ATOM   9445  N  N    . THR   B 1 314 ? 32.573  2.510   56.485  1.00 35.64 ? 313 THR   B N    1 
ATOM   9446  C  CA   . THR   B 1 314 ? 32.803  1.367   57.362  1.00 38.90 ? 313 THR   B CA   1 
ATOM   9447  C  C    . THR   B 1 314 ? 33.775  0.363   56.752  1.00 44.91 ? 313 THR   B C    1 
ATOM   9448  O  O    . THR   B 1 314 ? 34.090  -0.646  57.391  1.00 48.67 ? 313 THR   B O    1 
ATOM   9449  C  CB   . THR   B 1 314 ? 31.475  0.681   57.712  1.00 39.24 ? 313 THR   B CB   1 
ATOM   9450  O  OG1  . THR   B 1 314 ? 30.729  0.400   56.521  1.00 44.75 ? 313 THR   B OG1  1 
ATOM   9451  C  CG2  . THR   B 1 314 ? 30.657  1.579   58.612  1.00 44.82 ? 313 THR   B CG2  1 
ATOM   9452  H  H    . THR   B 1 314 ? 32.044  2.337   55.829  1.00 42.77 ? 313 THR   B H    1 
ATOM   9453  H  HA   . THR   B 1 314 ? 33.183  1.681   58.198  1.00 46.68 ? 313 THR   B HA   1 
ATOM   9454  H  HB   . THR   B 1 314 ? 31.655  -0.155  58.170  1.00 47.09 ? 313 THR   B HB   1 
ATOM   9455  H  HG1  . THR   B 1 314 ? 31.194  -0.057  55.991  1.00 53.70 ? 313 THR   B HG1  1 
ATOM   9456  H  HG21 . THR   B 1 314 ? 30.069  1.045   59.168  1.00 53.78 ? 313 THR   B HG21 1 
ATOM   9457  H  HG22 . THR   B 1 314 ? 31.243  2.100   59.182  1.00 53.78 ? 313 THR   B HG22 1 
ATOM   9458  H  HG23 . THR   B 1 314 ? 30.120  2.184   58.077  1.00 53.78 ? 313 THR   B HG23 1 
ATOM   9459  N  N    . ILE   B 1 315 ? 34.270  0.620   55.540  1.00 38.27 ? 314 ILE   B N    1 
ATOM   9460  C  CA   . ILE   B 1 315 ? 35.295  -0.227  54.933  1.00 38.38 ? 314 ILE   B CA   1 
ATOM   9461  C  C    . ILE   B 1 315 ? 36.583  -0.124  55.753  1.00 48.96 ? 314 ILE   B C    1 
ATOM   9462  O  O    . ILE   B 1 315 ? 37.144  -1.144  56.167  1.00 59.67 ? 314 ILE   B O    1 
ATOM   9463  C  CB   . ILE   B 1 315 ? 35.564  0.154   53.463  1.00 39.28 ? 314 ILE   B CB   1 
ATOM   9464  C  CG1  . ILE   B 1 315 ? 34.326  -0.110  52.589  1.00 44.45 ? 314 ILE   B CG1  1 
ATOM   9465  C  CG2  . ILE   B 1 315 ? 36.801  -0.575  52.938  1.00 38.95 ? 314 ILE   B CG2  1 
ATOM   9466  C  CD1  . ILE   B 1 315 ? 34.505  0.297   51.113  1.00 33.67 ? 314 ILE   B CD1  1 
HETATM 9467  C  C02  . A1LZ8 C 2 .   ? 16.644  20.800  -5.687  1.00 16.25 ? 401 A1LZ8 A C02  1 
HETATM 9468  C  C03  . A1LZ8 C 2 .   ? 16.398  19.329  -5.911  1.00 15.13 ? 401 A1LZ8 A C03  1 
HETATM 9469  C  C04  . A1LZ8 C 2 .   ? 15.181  18.887  -6.427  1.00 18.06 ? 401 A1LZ8 A C04  1 
HETATM 9470  C  C05  . A1LZ8 C 2 .   ? 15.092  17.494  -6.622  1.00 18.18 ? 401 A1LZ8 A C05  1 
HETATM 9471  C  C07  . A1LZ8 C 2 .   ? 12.517  17.970  -7.382  1.00 25.57 ? 401 A1LZ8 A C07  1 
HETATM 9472  C  C08  . A1LZ8 C 2 .   ? 11.371  17.117  -7.765  1.00 30.82 ? 401 A1LZ8 A C08  1 
HETATM 9473  C  C09  . A1LZ8 C 2 .   ? 11.807  16.059  -8.647  1.00 28.67 ? 401 A1LZ8 A C09  1 
HETATM 9474  C  C10  . A1LZ8 C 2 .   ? 12.158  15.107  -7.618  1.00 28.89 ? 401 A1LZ8 A C10  1 
HETATM 9475  C  C11  . A1LZ8 C 2 .   ? 13.557  15.321  -7.164  1.00 25.86 ? 401 A1LZ8 A C11  1 
HETATM 9476  C  C13  . A1LZ8 C 2 .   ? 16.122  16.584  -6.336  1.00 16.29 ? 401 A1LZ8 A C13  1 
HETATM 9477  C  C14  . A1LZ8 C 2 .   ? 17.326  17.092  -5.832  1.00 15.11 ? 401 A1LZ8 A C14  1 
HETATM 9478  C  C15  . A1LZ8 C 2 .   ? 17.448  18.473  -5.623  1.00 15.24 ? 401 A1LZ8 A C15  1 
HETATM 9479  C  C16  . A1LZ8 C 2 .   ? 18.751  19.094  -5.037  1.00 14.99 ? 401 A1LZ8 A C16  1 
HETATM 9480  C  C18  . A1LZ8 C 2 .   ? 16.012  22.693  -4.114  1.00 15.12 ? 401 A1LZ8 A C18  1 
HETATM 9481  C  C19  . A1LZ8 C 2 .   ? 15.623  23.753  -5.098  1.00 15.43 ? 401 A1LZ8 A C19  1 
HETATM 9482  C  C20  . A1LZ8 C 2 .   ? 16.656  24.436  -5.884  1.00 17.92 ? 401 A1LZ8 A C20  1 
HETATM 9483  C  C21  . A1LZ8 C 2 .   ? 16.316  25.490  -6.765  1.00 27.54 ? 401 A1LZ8 A C21  1 
HETATM 9484  C  C22  . A1LZ8 C 2 .   ? 14.934  25.812  -6.817  1.00 21.64 ? 401 A1LZ8 A C22  1 
HETATM 9485  C  C23  . A1LZ8 C 2 .   ? 13.961  25.099  -6.028  1.00 24.14 ? 401 A1LZ8 A C23  1 
HETATM 9486  C  C24  . A1LZ8 C 2 .   ? 14.247  24.106  -5.127  1.00 18.91 ? 401 A1LZ8 A C24  1 
HETATM 9487  C  C25  . A1LZ8 C 2 .   ? 13.202  23.443  -4.400  1.00 20.08 ? 401 A1LZ8 A C25  1 
HETATM 9488  C  C26  . A1LZ8 C 2 .   ? 11.831  23.914  -4.587  1.00 27.09 ? 401 A1LZ8 A C26  1 
HETATM 9489  C  C27  . A1LZ8 C 2 .   ? 11.560  25.000  -5.505  1.00 28.47 ? 401 A1LZ8 A C27  1 
HETATM 9490  C  C28  . A1LZ8 C 2 .   ? 12.645  25.577  -6.221  1.00 24.75 ? 401 A1LZ8 A C28  1 
HETATM 9491  C  C29  . A1LZ8 C 2 .   ? 12.772  26.669  -7.242  1.00 23.16 ? 401 A1LZ8 A C29  1 
HETATM 9492  C  C32  . A1LZ8 C 2 .   ? 14.751  27.754  -8.546  1.00 31.18 ? 401 A1LZ8 A C32  1 
HETATM 9493  C  C33  . A1LZ8 C 2 .   ? 16.072  22.681  -2.582  1.00 13.31 ? 401 A1LZ8 A C33  1 
HETATM 9494  C  C34  . A1LZ8 C 2 .   ? 17.366  22.919  -3.426  1.00 16.30 ? 401 A1LZ8 A C34  1 
HETATM 9495  N  N06  . A1LZ8 C 2 .   ? 13.836  16.972  -7.150  1.00 18.34 ? 401 A1LZ8 A N06  1 
HETATM 9496  N  N12  . A1LZ8 C 2 .   ? 11.322  15.984  -7.065  1.00 29.05 ? 401 A1LZ8 A N12  1 
HETATM 9497  N  N17  . A1LZ8 C 2 .   ? 15.900  21.318  -4.575  1.00 13.82 ? 401 A1LZ8 A N17  1 
HETATM 9498  N  N31  . A1LZ8 C 2 .   ? 14.163  26.806  -7.620  1.00 24.72 ? 401 A1LZ8 A N31  1 
HETATM 9499  O  O01  . A1LZ8 C 2 .   ? 17.398  21.444  -6.363  1.00 18.36 ? 401 A1LZ8 A O01  1 
HETATM 9500  O  O30  . A1LZ8 C 2 .   ? 11.844  27.285  -7.611  1.00 31.86 ? 401 A1LZ8 A O30  1 
HETATM 9501  ZN ZN   . ZN    D 3 .   ? -9.579  37.409  0.434   1.00 79.15 ? 402 ZN    A ZN   1 
HETATM 9502  ZN ZN   . ZN    E 3 .   ? 26.366  16.362  -3.693  0.49 27.77 ? 403 ZN    A ZN   1 
HETATM 9503  C  C1   . GOL   F 4 .   ? 15.660  33.539  11.008  1.00 34.19 ? 404 GOL   A C1   1 
HETATM 9504  O  O1   . GOL   F 4 .   ? 16.042  32.264  10.774  1.00 29.44 ? 404 GOL   A O1   1 
HETATM 9505  C  C2   . GOL   F 4 .   ? 16.859  34.131  11.799  1.00 51.09 ? 404 GOL   A C2   1 
HETATM 9506  O  O2   . GOL   F 4 .   ? 17.163  35.400  11.313  1.00 47.33 ? 404 GOL   A O2   1 
HETATM 9507  C  C3   . GOL   F 4 .   ? 18.002  33.102  11.526  1.00 32.28 ? 404 GOL   A C3   1 
HETATM 9508  O  O3   . GOL   F 4 .   ? 19.122  33.637  12.035  1.00 31.48 ? 404 GOL   A O3   1 
HETATM 9509  H  H11  . GOL   F 4 .   ? 14.720  33.598  11.599  1.00 41.03 ? 404 GOL   A H11  1 
HETATM 9510  H  H12  . GOL   F 4 .   ? 15.477  34.106  10.069  1.00 41.03 ? 404 GOL   A H12  1 
HETATM 9511  H  HO1  . GOL   F 4 .   ? 15.916  31.788  11.591  1.00 35.33 ? 404 GOL   A HO1  1 
HETATM 9512  H  H2   . GOL   F 4 .   ? 16.649  34.214  12.896  1.00 61.30 ? 404 GOL   A H2   1 
HETATM 9513  H  HO2  . GOL   F 4 .   ? 17.477  35.308  10.449  1.00 56.80 ? 404 GOL   A HO2  1 
HETATM 9514  H  H31  . GOL   F 4 .   ? 17.762  32.122  11.998  1.00 38.74 ? 404 GOL   A H31  1 
HETATM 9515  H  H32  . GOL   F 4 .   ? 18.097  32.908  10.433  1.00 38.74 ? 404 GOL   A H32  1 
HETATM 9516  H  HO3  . GOL   F 4 .   ? 18.932  34.561  12.169  1.00 37.78 ? 404 GOL   A HO3  1 
HETATM 9517  C  C1   . GOL   G 4 .   ? 16.730  27.858  19.760  1.00 37.46 ? 405 GOL   A C1   1 
HETATM 9518  O  O1   . GOL   G 4 .   ? 17.573  28.831  20.300  1.00 40.02 ? 405 GOL   A O1   1 
HETATM 9519  C  C2   . GOL   G 4 .   ? 16.486  28.282  18.309  1.00 46.00 ? 405 GOL   A C2   1 
HETATM 9520  O  O2   . GOL   G 4 .   ? 15.684  29.403  18.441  1.00 52.06 ? 405 GOL   A O2   1 
HETATM 9521  C  C3   . GOL   G 4 .   ? 15.725  27.103  17.689  1.00 29.97 ? 405 GOL   A C3   1 
HETATM 9522  O  O3   . GOL   G 4 .   ? 14.349  27.401  17.969  1.00 44.23 ? 405 GOL   A O3   1 
HETATM 9523  H  H11  . GOL   G 4 .   ? 15.769  27.789  20.314  1.00 44.95 ? 405 GOL   A H11  1 
HETATM 9524  H  H12  . GOL   G 4 .   ? 17.189  26.846  19.799  1.00 44.95 ? 405 GOL   A H12  1 
HETATM 9525  H  HO1  . GOL   G 4 .   ? 17.816  28.528  21.174  1.00 48.02 ? 405 GOL   A HO1  1 
HETATM 9526  H  H2   . GOL   G 4 .   ? 17.405  28.470  17.698  1.00 55.20 ? 405 GOL   A H2   1 
HETATM 9527  H  HO2  . GOL   G 4 .   ? 16.273  30.160  18.446  1.00 62.48 ? 405 GOL   A HO2  1 
HETATM 9528  H  H31  . GOL   G 4 .   ? 15.928  27.025  16.597  1.00 35.96 ? 405 GOL   A H31  1 
HETATM 9529  H  H32  . GOL   G 4 .   ? 16.049  26.136  18.137  1.00 35.96 ? 405 GOL   A H32  1 
HETATM 9530  H  HO3  . GOL   G 4 .   ? 14.010  26.668  18.483  1.00 53.08 ? 405 GOL   A HO3  1 
HETATM 9531  C  C02  . A1LZ8 H 2 .   ? 26.446  17.869  26.362  1.00 19.38 ? 401 A1LZ8 B C02  1 
HETATM 9532  C  C03  . A1LZ8 H 2 .   ? 26.780  19.345  26.214  1.00 14.41 ? 401 A1LZ8 B C03  1 
HETATM 9533  C  C04  . A1LZ8 H 2 .   ? 28.095  19.742  26.124  1.00 15.93 ? 401 A1LZ8 B C04  1 
HETATM 9534  C  C05  . A1LZ8 H 2 .   ? 28.304  21.120  25.982  1.00 21.59 ? 401 A1LZ8 B C05  1 
HETATM 9535  C  C07  . A1LZ8 H 2 .   ? 30.943  20.546  26.007  1.00 22.89 ? 401 A1LZ8 B C07  1 
HETATM 9536  C  C08  . A1LZ8 H 2 .   ? 32.203  21.314  25.947  1.00 30.23 ? 401 A1LZ8 B C08  1 
HETATM 9537  C  C09  . A1LZ8 H 2 .   ? 32.093  22.382  24.974  1.00 26.98 ? 401 A1LZ8 B C09  1 
HETATM 9538  C  C10  . A1LZ8 H 2 .   ? 31.558  23.366  25.896  1.00 25.93 ? 401 A1LZ8 B C10  1 
HETATM 9539  C  C11  . A1LZ8 H 2 .   ? 30.077  23.235  25.952  1.00 25.66 ? 401 A1LZ8 B C11  1 
HETATM 9540  C  C13  . A1LZ8 H 2 .   ? 27.266  22.021  25.911  1.00 19.00 ? 401 A1LZ8 B C13  1 
HETATM 9541  C  C14  . A1LZ8 H 2 .   ? 25.948  21.592  26.008  1.00 20.06 ? 401 A1LZ8 B C14  1 
HETATM 9542  C  C15  . A1LZ8 H 2 .   ? 25.712  20.247  26.170  1.00 14.48 ? 401 A1LZ8 B C15  1 
HETATM 9543  C  C16  . A1LZ8 H 2 .   ? 24.246  19.762  26.277  1.00 16.09 ? 401 A1LZ8 B C16  1 
HETATM 9544  C  C18  . A1LZ8 H 2 .   ? 26.393  15.951  28.033  1.00 18.70 ? 401 A1LZ8 B C18  1 
HETATM 9545  C  C19  . A1LZ8 H 2 .   ? 27.011  14.830  27.208  1.00 20.85 ? 401 A1LZ8 B C19  1 
HETATM 9546  C  C20  . A1LZ8 H 2 .   ? 26.287  14.115  26.149  1.00 18.84 ? 401 A1LZ8 B C20  1 
HETATM 9547  C  C21  . A1LZ8 H 2 .   ? 26.902  13.048  25.425  1.00 27.16 ? 401 A1LZ8 B C21  1 
HETATM 9548  C  C22  . A1LZ8 H 2 .   ? 28.221  12.686  25.790  1.00 26.35 ? 401 A1LZ8 B C22  1 
HETATM 9549  C  C23  . A1LZ8 H 2 .   ? 28.882  13.410  26.845  1.00 24.26 ? 401 A1LZ8 B C23  1 
HETATM 9550  C  C24  . A1LZ8 H 2 .   ? 28.330  14.440  27.562  1.00 23.53 ? 401 A1LZ8 B C24  1 
HETATM 9551  C  C25  . A1LZ8 H 2 .   ? 29.094  15.094  28.605  1.00 26.56 ? 401 A1LZ8 B C25  1 
HETATM 9552  C  C26  . A1LZ8 H 2 .   ? 30.439  14.610  28.854  1.00 33.75 ? 401 A1LZ8 B C26  1 
HETATM 9553  C  C27  . A1LZ8 H 2 .   ? 30.987  13.515  28.092  1.00 34.45 ? 401 A1LZ8 B C27  1 
HETATM 9554  C  C28  . A1LZ8 H 2 .   ? 30.191  12.916  27.077  1.00 29.74 ? 401 A1LZ8 B C28  1 
HETATM 9555  C  C29  . A1LZ8 H 2 .   ? 30.394  11.791  26.103  1.00 28.44 ? 401 A1LZ8 B C29  1 
HETATM 9556  C  C32  . A1LZ8 H 2 .   ? 28.971  10.680  24.259  1.00 35.90 ? 401 A1LZ8 B C32  1 
HETATM 9557  C  C33  . A1LZ8 H 2 .   ? 25.898  15.969  29.477  1.00 15.85 ? 401 A1LZ8 B C33  1 
HETATM 9558  C  C34  . A1LZ8 H 2 .   ? 24.889  15.836  28.309  1.00 18.04 ? 401 A1LZ8 B C34  1 
HETATM 9559  N  N06  . A1LZ8 H 2 .   ? 29.678  21.614  25.856  1.00 19.62 ? 401 A1LZ8 B N06  1 
HETATM 9560  N  N12  . A1LZ8 H 2 .   ? 32.159  22.442  26.657  1.00 26.69 ? 401 A1LZ8 B N12  1 
HETATM 9561  N  N17  . A1LZ8 H 2 .   ? 26.744  17.339  27.673  1.00 16.68 ? 401 A1LZ8 B N17  1 
HETATM 9562  N  N31  . A1LZ8 H 2 .   ? 29.203  11.651  25.324  1.00 30.20 ? 401 A1LZ8 B N31  1 
HETATM 9563  O  O01  . A1LZ8 H 2 .   ? 25.944  17.235  25.486  1.00 20.40 ? 401 A1LZ8 B O01  1 
HETATM 9564  O  O30  . A1LZ8 H 2 .   ? 31.397  11.148  26.017  1.00 39.88 ? 401 A1LZ8 B O30  1 
HETATM 9565  ZN ZN   . ZN    I 3 .   ? 49.054  -0.151  40.352  1.00 55.27 ? 402 ZN    B ZN   1 
HETATM 9566  ZN ZN   . ZN    J 3 .   ? 16.936  22.848  25.073  0.48 24.97 ? 403 ZN    B ZN   1 
HETATM 9567  C  C1   . GOL   K 4 .   ? 29.406  32.152  24.474  1.00 47.78 ? 404 GOL   B C1   1 
HETATM 9568  O  O1   . GOL   K 4 .   ? 28.168  32.815  24.456  1.00 41.46 ? 404 GOL   B O1   1 
HETATM 9569  C  C2   . GOL   K 4 .   ? 30.158  32.805  23.287  1.00 51.72 ? 404 GOL   B C2   1 
HETATM 9570  O  O2   . GOL   K 4 .   ? 29.673  34.087  23.203  1.00 62.57 ? 404 GOL   B O2   1 
HETATM 9571  C  C3   . GOL   K 4 .   ? 29.628  32.032  22.094  1.00 42.72 ? 404 GOL   B C3   1 
HETATM 9572  O  O3   . GOL   K 4 .   ? 29.916  32.866  20.971  1.00 59.84 ? 404 GOL   B O3   1 
HETATM 9573  H  H11  . GOL   K 4 .   ? 29.304  31.053  24.335  1.00 57.33 ? 404 GOL   B H11  1 
HETATM 9574  H  H12  . GOL   K 4 .   ? 29.954  32.298  25.430  1.00 57.33 ? 404 GOL   B H12  1 
HETATM 9575  H  HO1  . GOL   K 4 .   ? 28.354  33.742  24.271  1.00 49.75 ? 404 GOL   B HO1  1 
HETATM 9576  H  H2   . GOL   K 4 .   ? 31.273  32.755  23.375  1.00 62.07 ? 404 GOL   B H2   1 
HETATM 9577  H  HO2  . GOL   K 4 .   ? 29.336  34.192  22.329  1.00 75.09 ? 404 GOL   B HO2  1 
HETATM 9578  H  H31  . GOL   K 4 .   ? 30.121  31.036  22.016  1.00 51.26 ? 404 GOL   B H31  1 
HETATM 9579  H  H32  . GOL   K 4 .   ? 28.538  31.833  22.203  1.00 51.26 ? 404 GOL   B H32  1 
HETATM 9580  H  HO3  . GOL   K 4 .   ? 30.820  33.152  21.052  1.00 71.81 ? 404 GOL   B HO3  1 
HETATM 9581  C  C1   . GOL   L 4 .   ? 15.610  16.170  21.573  1.00 42.26 ? 405 GOL   B C1   1 
HETATM 9582  O  O1   . GOL   L 4 .   ? 15.862  15.103  22.493  1.00 43.70 ? 405 GOL   B O1   1 
HETATM 9583  C  C2   . GOL   L 4 .   ? 16.992  16.775  21.237  1.00 40.68 ? 405 GOL   B C2   1 
HETATM 9584  O  O2   . GOL   L 4 .   ? 16.893  18.189  21.251  1.00 44.89 ? 405 GOL   B O2   1 
HETATM 9585  C  C3   . GOL   L 4 .   ? 17.374  16.317  19.818  1.00 36.22 ? 405 GOL   B C3   1 
HETATM 9586  O  O3   . GOL   L 4 .   ? 17.359  14.883  19.859  1.00 44.75 ? 405 GOL   B O3   1 
HETATM 9587  H  H11  . GOL   L 4 .   ? 14.942  16.944  22.012  1.00 50.71 ? 405 GOL   B H11  1 
HETATM 9588  H  H12  . GOL   L 4 .   ? 15.108  15.808  20.649  1.00 50.71 ? 405 GOL   B H12  1 
HETATM 9589  H  HO1  . GOL   L 4 .   ? 16.433  15.462  23.168  1.00 52.44 ? 405 GOL   B HO1  1 
HETATM 9590  H  H2   . GOL   L 4 .   ? 17.741  16.391  21.976  1.00 48.82 ? 405 GOL   B H2   1 
HETATM 9591  H  HO2  . GOL   L 4 .   ? 16.198  18.452  20.676  1.00 53.86 ? 405 GOL   B HO2  1 
HETATM 9592  H  H31  . GOL   L 4 .   ? 16.654  16.720  19.070  1.00 43.46 ? 405 GOL   B H31  1 
HETATM 9593  H  H32  . GOL   L 4 .   ? 18.375  16.716  19.535  1.00 43.46 ? 405 GOL   B H32  1 
HETATM 9594  H  HO3  . GOL   L 4 .   ? 16.595  14.578  19.379  1.00 53.70 ? 405 GOL   B HO3  1 
HETATM 9595  O  O    . HOH   M 5 .   ? 10.710  -19.665 2.354   1.00 60.21 ? 501 HOH   A O    1 
HETATM 9596  O  O    . HOH   M 5 .   ? 23.493  33.442  -2.905  1.00 41.65 ? 502 HOH   A O    1 
HETATM 9597  O  O    . HOH   M 5 .   ? 19.619  -5.669  -5.410  1.00 37.78 ? 503 HOH   A O    1 
HETATM 9598  O  O    . HOH   M 5 .   ? -12.356 34.336  11.833  1.00 48.81 ? 504 HOH   A O    1 
HETATM 9599  O  O    . HOH   M 5 .   ? 13.315  3.409   -6.907  1.00 35.84 ? 505 HOH   A O    1 
HETATM 9600  O  O    . HOH   M 5 .   ? 12.253  32.104  16.946  1.00 50.59 ? 506 HOH   A O    1 
HETATM 9601  O  O    . HOH   M 5 .   ? 31.041  24.763  21.905  1.00 43.24 ? 507 HOH   A O    1 
HETATM 9602  O  O    . HOH   M 5 .   ? 21.332  9.253   -3.749  1.00 16.60 ? 508 HOH   A O    1 
HETATM 9603  O  O    . HOH   M 5 .   ? 21.830  21.514  17.357  1.00 31.69 ? 509 HOH   A O    1 
HETATM 9604  O  O    . HOH   M 5 .   ? 27.933  10.542  16.960  1.00 40.58 ? 510 HOH   A O    1 
HETATM 9605  O  O    . HOH   M 5 .   ? 15.204  8.762   -9.564  1.00 39.11 ? 511 HOH   A O    1 
HETATM 9606  O  O    . HOH   M 5 .   ? 15.127  -14.755 -2.067  1.00 33.67 ? 512 HOH   A O    1 
HETATM 9607  O  O    . HOH   M 5 .   ? 32.631  21.482  -0.835  1.00 35.44 ? 513 HOH   A O    1 
HETATM 9608  O  O    . HOH   M 5 .   ? 7.518   3.474   2.627   1.00 46.87 ? 514 HOH   A O    1 
HETATM 9609  O  O    . HOH   M 5 .   ? 2.006   34.656  15.934  1.00 24.63 ? 515 HOH   A O    1 
HETATM 9610  O  O    . HOH   M 5 .   ? -0.804  18.431  20.655  1.00 45.06 ? 516 HOH   A O    1 
HETATM 9611  O  O    . HOH   M 5 .   ? 29.128  28.224  3.307   1.00 38.25 ? 517 HOH   A O    1 
HETATM 9612  O  O    . HOH   M 5 .   ? 17.977  -2.896  8.680   1.00 34.86 ? 518 HOH   A O    1 
HETATM 9613  O  O    . HOH   M 5 .   ? 31.327  7.581   12.885  1.00 28.87 ? 519 HOH   A O    1 
HETATM 9614  O  O    . HOH   M 5 .   ? 27.862  18.855  2.474   1.00 24.37 ? 520 HOH   A O    1 
HETATM 9615  O  O    . HOH   M 5 .   ? 34.689  28.586  18.571  1.00 32.10 ? 521 HOH   A O    1 
HETATM 9616  O  O    . HOH   M 5 .   ? 30.623  -6.532  3.470   1.00 43.25 ? 522 HOH   A O    1 
HETATM 9617  O  O    . HOH   M 5 .   ? 16.711  12.930  -7.103  1.00 33.16 ? 523 HOH   A O    1 
HETATM 9618  O  O    . HOH   M 5 .   ? 29.395  27.493  0.199   1.00 35.08 ? 524 HOH   A O    1 
HETATM 9619  O  O    . HOH   M 5 .   ? 10.004  20.170  22.711  1.00 29.01 ? 525 HOH   A O    1 
HETATM 9620  O  O    . HOH   M 5 .   ? 32.735  3.244   7.052   1.00 35.50 ? 526 HOH   A O    1 
HETATM 9621  O  O    . HOH   M 5 .   ? 32.194  28.666  7.758   1.00 34.80 ? 527 HOH   A O    1 
HETATM 9622  O  O    . HOH   M 5 .   ? 36.136  15.117  9.311   1.00 32.48 ? 528 HOH   A O    1 
HETATM 9623  O  O    . HOH   M 5 .   ? 29.113  25.017  -2.681  1.00 37.85 ? 529 HOH   A O    1 
HETATM 9624  O  O    . HOH   M 5 .   ? 23.080  -12.012 11.869  1.00 28.37 ? 530 HOH   A O    1 
HETATM 9625  O  O    . HOH   M 5 .   ? 20.074  15.729  19.648  1.00 21.00 ? 531 HOH   A O    1 
HETATM 9626  O  O    . HOH   M 5 .   ? 13.221  -6.832  -3.364  1.00 32.86 ? 532 HOH   A O    1 
HETATM 9627  O  O    . HOH   M 5 .   ? 2.283   10.887  12.744  1.00 36.58 ? 533 HOH   A O    1 
HETATM 9628  O  O    . HOH   M 5 .   ? 19.077  39.407  8.771   1.00 40.33 ? 534 HOH   A O    1 
HETATM 9629  O  O    . HOH   M 5 .   ? 21.773  24.171  17.031  1.00 28.15 ? 535 HOH   A O    1 
HETATM 9630  O  O    . HOH   M 5 .   ? 10.376  -16.746 13.013  1.00 43.99 ? 536 HOH   A O    1 
HETATM 9631  O  O    . HOH   M 5 .   ? 15.816  19.851  -13.462 1.00 35.05 ? 537 HOH   A O    1 
HETATM 9632  O  O    . HOH   M 5 .   ? 23.120  -8.875  2.961   1.00 41.18 ? 538 HOH   A O    1 
HETATM 9633  O  O    . HOH   M 5 .   ? 25.425  -15.099 11.468  1.00 24.26 ? 539 HOH   A O    1 
HETATM 9634  O  O    . HOH   M 5 .   ? 30.768  -24.522 -3.497  1.00 36.03 ? 540 HOH   A O    1 
HETATM 9635  O  O    . HOH   M 5 .   ? 2.140   28.137  24.319  1.00 28.19 ? 541 HOH   A O    1 
HETATM 9636  O  O    . HOH   M 5 .   ? 9.702   6.571   -1.942  1.00 31.43 ? 542 HOH   A O    1 
HETATM 9637  O  O    . HOH   M 5 .   ? 17.588  -5.290  8.513   1.00 32.25 ? 543 HOH   A O    1 
HETATM 9638  O  O    . HOH   M 5 .   ? 25.957  38.663  9.024   1.00 42.60 ? 544 HOH   A O    1 
HETATM 9639  O  O    . HOH   M 5 .   ? 12.716  21.765  -1.438  1.00 17.77 ? 545 HOH   A O    1 
HETATM 9640  O  O    . HOH   M 5 .   ? 32.613  -18.827 8.716   1.00 41.92 ? 546 HOH   A O    1 
HETATM 9641  O  O    . HOH   M 5 .   ? -0.243  15.666  8.318   1.00 33.99 ? 547 HOH   A O    1 
HETATM 9642  O  O    . HOH   M 5 .   ? 8.520   11.818  16.527  1.00 29.45 ? 548 HOH   A O    1 
HETATM 9643  O  O    . HOH   M 5 .   ? -4.820  35.506  16.857  1.00 40.61 ? 549 HOH   A O    1 
HETATM 9644  O  O    . HOH   M 5 .   ? 23.367  42.362  7.737   1.00 36.28 ? 550 HOH   A O    1 
HETATM 9645  O  O    . HOH   M 5 .   ? 22.912  2.677   10.762  1.00 22.98 ? 551 HOH   A O    1 
HETATM 9646  O  O    . HOH   M 5 .   ? 26.500  24.679  -0.863  1.00 23.11 ? 552 HOH   A O    1 
HETATM 9647  O  O    . HOH   M 5 .   ? 25.339  36.269  10.900  1.00 29.13 ? 553 HOH   A O    1 
HETATM 9648  O  O    . HOH   M 5 .   ? 6.167   -3.081  13.716  1.00 30.53 ? 554 HOH   A O    1 
HETATM 9649  O  O    . HOH   M 5 .   ? 18.478  24.027  18.996  1.00 33.53 ? 555 HOH   A O    1 
HETATM 9650  O  O    . HOH   M 5 .   ? 23.097  27.909  19.485  1.00 29.75 ? 556 HOH   A O    1 
HETATM 9651  O  O    . HOH   M 5 .   ? 14.474  8.509   18.487  1.00 38.42 ? 557 HOH   A O    1 
HETATM 9652  O  O    . HOH   M 5 .   ? 35.192  12.876  -0.854  1.00 19.06 ? 558 HOH   A O    1 
HETATM 9653  O  O    . HOH   M 5 .   ? 2.144   40.831  13.070  1.00 43.61 ? 559 HOH   A O    1 
HETATM 9654  O  O    . HOH   M 5 .   ? 2.249   22.162  6.170   1.00 37.25 ? 560 HOH   A O    1 
HETATM 9655  O  O    . HOH   M 5 .   ? 33.307  14.224  17.704  1.00 37.79 ? 561 HOH   A O    1 
HETATM 9656  O  O    . HOH   M 5 .   ? 25.575  17.156  -6.838  1.00 34.84 ? 562 HOH   A O    1 
HETATM 9657  O  O    . HOH   M 5 .   ? 7.744   36.444  18.037  1.00 44.77 ? 563 HOH   A O    1 
HETATM 9658  O  O    . HOH   M 5 .   ? 22.720  23.022  20.041  1.00 33.62 ? 564 HOH   A O    1 
HETATM 9659  O  O    . HOH   M 5 .   ? 16.025  20.994  0.743   1.00 17.43 ? 565 HOH   A O    1 
HETATM 9660  O  O    . HOH   M 5 .   ? 10.370  -8.439  12.062  1.00 24.04 ? 566 HOH   A O    1 
HETATM 9661  O  O    . HOH   M 5 .   ? 19.895  21.127  7.581   1.00 22.84 ? 567 HOH   A O    1 
HETATM 9662  O  O    . HOH   M 5 .   ? -7.442  32.259  14.756  1.00 45.07 ? 568 HOH   A O    1 
HETATM 9663  O  O    . HOH   M 5 .   ? 28.407  7.825   -8.218  1.00 39.99 ? 569 HOH   A O    1 
HETATM 9664  O  O    . HOH   M 5 .   ? 7.048   24.782  9.636   1.00 19.61 ? 570 HOH   A O    1 
HETATM 9665  O  O    . HOH   M 5 .   ? 27.413  18.858  18.499  1.00 32.53 ? 571 HOH   A O    1 
HETATM 9666  O  O    . HOH   M 5 .   ? 29.538  -9.604  0.929   1.00 38.75 ? 572 HOH   A O    1 
HETATM 9667  O  O    . HOH   M 5 .   ? 21.520  28.532  -4.590  1.00 26.43 ? 573 HOH   A O    1 
HETATM 9668  O  O    . HOH   M 5 .   ? 24.113  8.582   -3.136  1.00 20.83 ? 574 HOH   A O    1 
HETATM 9669  O  O    . HOH   M 5 .   ? 16.335  5.038   17.626  1.00 31.82 ? 575 HOH   A O    1 
HETATM 9670  O  O    . HOH   M 5 .   ? 25.808  35.384  14.444  1.00 27.78 ? 576 HOH   A O    1 
HETATM 9671  O  O    . HOH   M 5 .   ? 13.818  -12.812 9.019   1.00 24.34 ? 577 HOH   A O    1 
HETATM 9672  O  O    . HOH   M 5 .   ? 6.042   -8.334  3.503   1.00 36.59 ? 578 HOH   A O    1 
HETATM 9673  O  O    . HOH   M 5 .   ? 30.396  32.342  7.187   1.00 46.81 ? 579 HOH   A O    1 
HETATM 9674  O  O    . HOH   M 5 .   ? -9.158  22.893  11.244  1.00 27.15 ? 580 HOH   A O    1 
HETATM 9675  O  O    . HOH   M 5 .   ? 14.195  23.132  0.486   1.00 18.66 ? 581 HOH   A O    1 
HETATM 9676  O  O    . HOH   M 5 .   ? 15.072  30.673  0.835   1.00 27.26 ? 582 HOH   A O    1 
HETATM 9677  O  O    . HOH   M 5 .   ? 14.542  32.866  15.003  1.00 32.75 ? 583 HOH   A O    1 
HETATM 9678  O  O    . HOH   M 5 .   ? 29.271  -30.135 -3.028  1.00 31.41 ? 584 HOH   A O    1 
HETATM 9679  O  O    . HOH   M 5 .   ? 22.861  5.705   19.910  1.00 34.26 ? 585 HOH   A O    1 
HETATM 9680  O  O    . HOH   M 5 .   ? 40.189  10.948  0.197   1.00 28.50 ? 586 HOH   A O    1 
HETATM 9681  O  O    . HOH   M 5 .   ? 4.689   31.850  2.115   1.00 32.63 ? 587 HOH   A O    1 
HETATM 9682  O  O    . HOH   M 5 .   ? 15.346  12.059  17.913  1.00 38.47 ? 588 HOH   A O    1 
HETATM 9683  O  O    . HOH   M 5 .   ? 3.992   34.509  22.475  1.00 41.79 ? 589 HOH   A O    1 
HETATM 9684  O  O    . HOH   M 5 .   ? 18.486  -5.438  12.080  1.00 40.73 ? 590 HOH   A O    1 
HETATM 9685  O  O    . HOH   M 5 .   ? 31.863  6.906   -5.044  1.00 38.52 ? 591 HOH   A O    1 
HETATM 9686  O  O    . HOH   M 5 .   ? 19.768  27.400  -6.065  1.00 31.99 ? 592 HOH   A O    1 
HETATM 9687  O  O    . HOH   M 5 .   ? 8.531   -9.932  13.575  1.00 46.09 ? 593 HOH   A O    1 
HETATM 9688  O  O    . HOH   M 5 .   ? 12.821  31.922  -2.090  1.00 30.67 ? 594 HOH   A O    1 
HETATM 9689  O  O    . HOH   M 5 .   ? 30.101  28.895  9.445   1.00 29.15 ? 595 HOH   A O    1 
HETATM 9690  O  O    . HOH   M 5 .   ? 20.774  -31.312 -1.840  1.00 46.79 ? 596 HOH   A O    1 
HETATM 9691  O  O    . HOH   M 5 .   ? 13.490  6.121   16.718  1.00 19.41 ? 597 HOH   A O    1 
HETATM 9692  O  O    . HOH   M 5 .   ? 14.144  -4.330  16.777  1.00 34.08 ? 598 HOH   A O    1 
HETATM 9693  O  O    . HOH   M 5 .   ? 31.530  -14.347 -0.622  1.00 41.15 ? 599 HOH   A O    1 
HETATM 9694  O  O    . HOH   M 5 .   ? 28.671  14.235  2.163   1.00 18.38 ? 600 HOH   A O    1 
HETATM 9695  O  O    . HOH   M 5 .   ? 14.447  -4.629  -5.807  1.00 34.70 ? 601 HOH   A O    1 
HETATM 9696  O  O    . HOH   M 5 .   ? 9.383   22.535  4.709   1.00 20.94 ? 602 HOH   A O    1 
HETATM 9697  O  O    . HOH   M 5 .   ? 26.476  -33.934 2.503   1.00 41.16 ? 603 HOH   A O    1 
HETATM 9698  O  O    . HOH   M 5 .   ? -3.038  17.317  19.146  1.00 46.84 ? 604 HOH   A O    1 
HETATM 9699  O  O    . HOH   M 5 .   ? 16.075  35.230  1.649   1.00 32.62 ? 605 HOH   A O    1 
HETATM 9700  O  O    . HOH   M 5 .   ? 11.491  19.988  -3.989  1.00 23.24 ? 606 HOH   A O    1 
HETATM 9701  O  O    . HOH   M 5 .   ? 14.527  16.623  -14.170 1.00 35.42 ? 607 HOH   A O    1 
HETATM 9702  O  O    . HOH   M 5 .   ? 32.301  8.558   2.022   1.00 20.65 ? 608 HOH   A O    1 
HETATM 9703  O  O    . HOH   M 5 .   ? 15.798  29.662  -5.804  1.00 25.46 ? 609 HOH   A O    1 
HETATM 9704  O  O    . HOH   M 5 .   ? 9.169   27.910  -7.001  1.00 45.73 ? 610 HOH   A O    1 
HETATM 9705  O  O    . HOH   M 5 .   ? 17.708  -1.684  11.026  1.00 22.39 ? 611 HOH   A O    1 
HETATM 9706  O  O    . HOH   M 5 .   ? 24.111  -5.509  -4.340  1.00 41.00 ? 612 HOH   A O    1 
HETATM 9707  O  O    . HOH   M 5 .   ? 13.543  18.846  18.673  1.00 23.32 ? 613 HOH   A O    1 
HETATM 9708  O  O    . HOH   M 5 .   ? 17.000  36.695  -0.361  1.00 38.23 ? 614 HOH   A O    1 
HETATM 9709  O  O    . HOH   M 5 .   ? 23.893  -10.271 5.195   1.00 26.19 ? 615 HOH   A O    1 
HETATM 9710  O  O    . HOH   M 5 .   ? 13.298  8.116   -7.911  1.00 41.08 ? 616 HOH   A O    1 
HETATM 9711  O  O    . HOH   M 5 .   ? 11.568  12.693  -5.056  1.00 41.41 ? 617 HOH   A O    1 
HETATM 9712  O  O    . HOH   M 5 .   ? 13.206  11.033  -7.958  1.00 40.34 ? 618 HOH   A O    1 
HETATM 9713  O  O    . HOH   M 5 .   ? 5.411   19.864  21.762  1.00 30.83 ? 619 HOH   A O    1 
HETATM 9714  O  O    . HOH   M 5 .   ? 8.239   33.650  19.996  1.00 28.42 ? 620 HOH   A O    1 
HETATM 9715  O  O    . HOH   M 5 .   ? 21.681  13.578  -9.554  1.00 22.80 ? 621 HOH   A O    1 
HETATM 9716  O  O    . HOH   M 5 .   ? -7.620  23.894  17.204  1.00 34.81 ? 622 HOH   A O    1 
HETATM 9717  O  O    . HOH   M 5 .   ? 4.166   13.771  18.191  1.00 34.71 ? 623 HOH   A O    1 
HETATM 9718  O  O    . HOH   M 5 .   ? 8.850   13.993  17.427  1.00 39.62 ? 624 HOH   A O    1 
HETATM 9719  O  O    . HOH   M 5 .   ? 18.863  1.127   -4.157  1.00 32.94 ? 625 HOH   A O    1 
HETATM 9720  O  O    . HOH   M 5 .   ? 10.754  39.188  11.269  1.00 48.29 ? 626 HOH   A O    1 
HETATM 9721  O  O    . HOH   M 5 .   ? 33.568  32.261  15.162  1.00 30.68 ? 627 HOH   A O    1 
HETATM 9722  O  O    . HOH   M 5 .   ? 26.001  -28.831 7.171   1.00 45.66 ? 628 HOH   A O    1 
HETATM 9723  O  O    . HOH   M 5 .   ? -3.928  28.563  3.437   1.00 47.49 ? 629 HOH   A O    1 
HETATM 9724  O  O    . HOH   M 5 .   ? 8.655   13.639  0.184   1.00 32.04 ? 630 HOH   A O    1 
HETATM 9725  O  O    . HOH   M 5 .   ? -9.796  26.359  17.823  1.00 46.83 ? 631 HOH   A O    1 
HETATM 9726  O  O    . HOH   M 5 .   ? 1.929   24.152  7.421   1.00 37.65 ? 632 HOH   A O    1 
HETATM 9727  O  O    . HOH   M 5 .   ? 27.396  18.065  5.264   1.00 20.02 ? 633 HOH   A O    1 
HETATM 9728  O  O    . HOH   M 5 .   ? 6.103   24.476  26.740  1.00 21.28 ? 634 HOH   A O    1 
HETATM 9729  O  O    . HOH   M 5 .   ? 3.807   20.686  24.866  1.00 41.28 ? 635 HOH   A O    1 
HETATM 9730  O  O    . HOH   M 5 .   ? -0.301  26.326  5.438   1.00 36.83 ? 636 HOH   A O    1 
HETATM 9731  O  O    . HOH   M 5 .   ? 19.147  15.066  -9.052  1.00 30.34 ? 637 HOH   A O    1 
HETATM 9732  O  O    . HOH   M 5 .   ? -7.375  21.232  8.456   1.00 39.59 ? 638 HOH   A O    1 
HETATM 9733  O  O    . HOH   M 5 .   ? -10.038 34.840  5.172   1.00 46.49 ? 639 HOH   A O    1 
HETATM 9734  O  O    . HOH   M 5 .   ? 26.888  -12.777 8.951   1.00 35.74 ? 640 HOH   A O    1 
HETATM 9735  O  O    . HOH   M 5 .   ? 0.757   29.303  2.304   1.00 40.23 ? 641 HOH   A O    1 
HETATM 9736  O  O    . HOH   M 5 .   ? 16.829  33.266  -5.103  1.00 39.25 ? 642 HOH   A O    1 
HETATM 9737  O  O    . HOH   M 5 .   ? 26.092  -7.117  -5.647  1.00 36.22 ? 643 HOH   A O    1 
HETATM 9738  O  O    . HOH   M 5 .   ? 16.972  -25.964 8.500   1.00 41.28 ? 644 HOH   A O    1 
HETATM 9739  O  O    . HOH   M 5 .   ? -10.157 33.032  12.984  1.00 41.42 ? 645 HOH   A O    1 
HETATM 9740  O  O    . HOH   M 5 .   ? 17.563  -26.068 5.318   1.00 41.08 ? 646 HOH   A O    1 
HETATM 9741  O  O    . HOH   M 5 .   ? 5.661   3.585   9.568   1.00 29.69 ? 647 HOH   A O    1 
HETATM 9742  O  O    . HOH   M 5 .   ? 14.613  13.987  -3.497  1.00 21.01 ? 648 HOH   A O    1 
HETATM 9743  O  O    . HOH   M 5 .   ? -3.394  18.004  9.031   1.00 29.49 ? 649 HOH   A O    1 
HETATM 9744  O  O    . HOH   M 5 .   ? 27.633  41.394  6.245   1.00 45.17 ? 650 HOH   A O    1 
HETATM 9745  O  O    . HOH   M 5 .   ? 22.845  36.383  17.419  1.00 36.94 ? 651 HOH   A O    1 
HETATM 9746  O  O    . HOH   M 5 .   ? 25.183  -13.076 -7.799  1.00 36.35 ? 652 HOH   A O    1 
HETATM 9747  O  O    . HOH   M 5 .   ? 24.916  -2.559  -5.246  1.00 33.30 ? 653 HOH   A O    1 
HETATM 9748  O  O    . HOH   M 5 .   ? 3.757   10.861  10.531  1.00 36.57 ? 654 HOH   A O    1 
HETATM 9749  O  O    . HOH   M 5 .   ? 32.857  -14.936 3.295   1.00 42.61 ? 655 HOH   A O    1 
HETATM 9750  O  O    . HOH   M 5 .   ? 32.965  24.080  2.868   1.00 32.67 ? 656 HOH   A O    1 
HETATM 9751  O  O    . HOH   M 5 .   ? 32.784  23.892  5.746   1.00 25.77 ? 657 HOH   A O    1 
HETATM 9752  O  O    . HOH   M 5 .   ? 8.231   17.906  -4.207  1.00 44.66 ? 658 HOH   A O    1 
HETATM 9753  O  O    . HOH   M 5 .   ? 25.568  38.475  0.964   1.00 38.54 ? 659 HOH   A O    1 
HETATM 9754  O  O    . HOH   M 5 .   ? 29.393  -31.698 -7.038  1.00 40.27 ? 660 HOH   A O    1 
HETATM 9755  O  O    . HOH   M 5 .   ? 14.551  -22.816 9.132   1.00 46.03 ? 661 HOH   A O    1 
HETATM 9756  O  O    . HOH   M 5 .   ? 25.447  3.823   -8.484  1.00 45.07 ? 662 HOH   A O    1 
HETATM 9757  O  O    . HOH   M 5 .   ? 35.746  10.856  13.122  1.00 34.81 ? 663 HOH   A O    1 
HETATM 9758  O  O    . HOH   M 5 .   ? 12.989  33.272  12.588  1.00 20.65 ? 664 HOH   A O    1 
HETATM 9759  O  O    . HOH   M 5 .   ? 33.408  15.500  2.425   1.00 19.07 ? 665 HOH   A O    1 
HETATM 9760  O  O    . HOH   M 5 .   ? 14.245  12.188  -1.430  1.00 23.93 ? 666 HOH   A O    1 
HETATM 9761  O  O    . HOH   M 5 .   ? 11.519  28.399  19.144  1.00 32.52 ? 667 HOH   A O    1 
HETATM 9762  O  O    . HOH   M 5 .   ? 36.246  15.602  12.230  1.00 45.43 ? 668 HOH   A O    1 
HETATM 9763  O  O    . HOH   M 5 .   ? 10.567  20.853  -6.169  1.00 30.49 ? 669 HOH   A O    1 
HETATM 9764  O  O    . HOH   M 5 .   ? 32.200  11.834  18.597  1.00 45.29 ? 670 HOH   A O    1 
HETATM 9765  O  O    . HOH   M 5 .   ? 18.788  35.692  -3.143  1.00 28.39 ? 671 HOH   A O    1 
HETATM 9766  O  O    . HOH   M 5 .   ? 12.968  37.535  9.537   1.00 46.36 ? 672 HOH   A O    1 
HETATM 9767  O  O    . HOH   M 5 .   ? 2.381   7.534   13.990  1.00 40.87 ? 673 HOH   A O    1 
HETATM 9768  O  O    . HOH   M 5 .   ? 3.589   24.739  3.162   1.00 27.93 ? 674 HOH   A O    1 
HETATM 9769  O  O    . HOH   M 5 .   ? 10.267  -10.133 15.569  1.00 46.84 ? 675 HOH   A O    1 
HETATM 9770  O  O    . HOH   M 5 .   ? 32.738  25.024  -1.404  1.00 46.92 ? 676 HOH   A O    1 
HETATM 9771  O  O    . HOH   M 5 .   ? -6.911  29.165  7.617   1.00 36.75 ? 677 HOH   A O    1 
HETATM 9772  O  O    . HOH   M 5 .   ? 26.890  12.484  20.462  1.00 30.58 ? 678 HOH   A O    1 
HETATM 9773  O  O    . HOH   M 5 .   ? 12.879  30.034  17.660  1.00 42.32 ? 679 HOH   A O    1 
HETATM 9774  O  O    . HOH   M 5 .   ? 8.606   15.026  -7.830  1.00 43.75 ? 680 HOH   A O    1 
HETATM 9775  O  O    . HOH   M 5 .   ? 33.579  5.499   8.931   1.00 26.67 ? 681 HOH   A O    1 
HETATM 9776  O  O    . HOH   M 5 .   ? 5.062   37.924  2.939   1.00 42.78 ? 682 HOH   A O    1 
HETATM 9777  O  O    . HOH   M 5 .   ? 20.768  26.106  18.424  1.00 33.31 ? 683 HOH   A O    1 
HETATM 9778  O  O    . HOH   M 5 .   ? 10.240  2.432   -0.703  1.00 32.45 ? 684 HOH   A O    1 
HETATM 9779  O  O    . HOH   M 5 .   ? 7.572   21.610  2.852   1.00 25.45 ? 685 HOH   A O    1 
HETATM 9780  O  O    . HOH   M 5 .   ? 33.407  -34.911 -6.812  1.00 38.38 ? 686 HOH   A O    1 
HETATM 9781  O  O    . HOH   M 5 .   ? 16.939  0.067   19.031  1.00 47.50 ? 687 HOH   A O    1 
HETATM 9782  O  O    . HOH   M 5 .   ? 12.451  33.497  3.606   1.00 24.84 ? 688 HOH   A O    1 
HETATM 9783  O  O    . HOH   M 5 .   ? 1.995   8.814   8.330   1.00 50.93 ? 689 HOH   A O    1 
HETATM 9784  O  O    . HOH   M 5 .   ? -7.380  29.037  18.431  1.00 44.36 ? 690 HOH   A O    1 
HETATM 9785  O  O    . HOH   M 5 .   ? 4.158   5.884   10.277  1.00 39.93 ? 691 HOH   A O    1 
HETATM 9786  O  O    . HOH   M 5 .   ? 7.718   -2.212  -6.911  1.00 45.34 ? 692 HOH   A O    1 
HETATM 9787  O  O    . HOH   M 5 .   ? 27.639  -32.616 4.890   1.00 48.32 ? 693 HOH   A O    1 
HETATM 9788  O  O    . HOH   M 5 .   ? 17.960  26.408  -11.003 1.00 37.01 ? 694 HOH   A O    1 
HETATM 9789  O  O    . HOH   M 5 .   ? 3.121   36.921  19.194  1.00 40.90 ? 695 HOH   A O    1 
HETATM 9790  O  O    . HOH   M 5 .   ? 3.942   17.844  20.473  1.00 41.91 ? 696 HOH   A O    1 
HETATM 9791  O  O    . HOH   M 5 .   ? 16.275  2.772   -3.774  1.00 27.28 ? 697 HOH   A O    1 
HETATM 9792  O  O    . HOH   M 5 .   ? 25.317  0.485   9.960   1.00 22.19 ? 698 HOH   A O    1 
HETATM 9793  O  O    . HOH   M 5 .   ? 22.738  15.899  -10.425 1.00 33.06 ? 699 HOH   A O    1 
HETATM 9794  O  O    . HOH   M 5 .   ? 26.226  -3.654  7.666   1.00 52.39 ? 700 HOH   A O    1 
HETATM 9795  O  O    . HOH   M 5 .   ? 31.807  17.516  1.024   1.00 23.90 ? 701 HOH   A O    1 
HETATM 9796  O  O    . HOH   M 5 .   ? -9.639  24.797  13.618  1.00 24.31 ? 702 HOH   A O    1 
HETATM 9797  O  O    . HOH   M 5 .   ? 23.998  29.206  -5.929  1.00 37.41 ? 703 HOH   A O    1 
HETATM 9798  O  O    . HOH   M 5 .   ? 12.185  -0.933  -7.746  1.00 43.01 ? 704 HOH   A O    1 
HETATM 9799  O  O    . HOH   M 5 .   ? 32.247  -35.959 0.251   1.00 40.85 ? 705 HOH   A O    1 
HETATM 9800  O  O    . HOH   M 5 .   ? 29.623  -31.810 3.713   1.00 47.09 ? 706 HOH   A O    1 
HETATM 9801  O  O    . HOH   M 5 .   ? 32.051  9.341   -5.665  1.00 27.12 ? 707 HOH   A O    1 
HETATM 9802  O  O    . HOH   M 5 .   ? 37.332  19.529  9.481   1.00 39.72 ? 708 HOH   A O    1 
HETATM 9803  O  O    . HOH   M 5 .   ? 35.250  17.143  15.966  1.00 41.89 ? 709 HOH   A O    1 
HETATM 9804  O  O    . HOH   M 5 .   ? 29.123  34.196  5.434   1.00 31.58 ? 710 HOH   A O    1 
HETATM 9805  O  O    . HOH   M 5 .   ? 28.376  2.121   9.489   1.00 29.89 ? 711 HOH   A O    1 
HETATM 9806  O  O    . HOH   M 5 .   ? 31.949  4.295   11.197  1.00 44.86 ? 712 HOH   A O    1 
HETATM 9807  O  O    . HOH   M 5 .   ? 6.425   13.101  1.331   1.00 50.30 ? 713 HOH   A O    1 
HETATM 9808  O  O    . HOH   M 5 .   ? 21.403  2.088   -5.138  1.00 33.51 ? 714 HOH   A O    1 
HETATM 9809  O  O    . HOH   M 5 .   ? -4.207  29.061  21.077  1.00 40.75 ? 715 HOH   A O    1 
HETATM 9810  O  O    . HOH   M 5 .   ? 14.651  -20.890 -6.294  1.00 51.96 ? 716 HOH   A O    1 
HETATM 9811  O  O    . HOH   M 5 .   ? 29.215  -6.506  -5.301  1.00 50.25 ? 717 HOH   A O    1 
HETATM 9812  O  O    . HOH   M 5 .   ? 1.675   8.305   20.679  1.00 47.82 ? 718 HOH   A O    1 
HETATM 9813  O  O    . HOH   M 5 .   ? 4.576   31.215  23.452  1.00 39.81 ? 719 HOH   A O    1 
HETATM 9814  O  O    . HOH   M 5 .   ? 38.037  21.768  6.896   1.00 42.63 ? 720 HOH   A O    1 
HETATM 9815  O  O    . HOH   M 5 .   ? -11.311 30.081  16.181  1.00 42.50 ? 721 HOH   A O    1 
HETATM 9816  O  O    . HOH   M 5 .   ? 7.718   18.341  22.027  1.00 41.17 ? 722 HOH   A O    1 
HETATM 9817  O  O    . HOH   M 5 .   ? 7.266   4.664   -4.743  1.00 36.61 ? 723 HOH   A O    1 
HETATM 9818  O  O    . HOH   M 5 .   ? 11.505  11.365  -0.849  1.00 33.34 ? 724 HOH   A O    1 
HETATM 9819  O  O    . HOH   M 5 .   ? 29.987  -34.698 2.288   1.00 51.97 ? 725 HOH   A O    1 
HETATM 9820  O  O    . HOH   M 5 .   ? 16.110  3.788   -6.423  1.00 36.03 ? 726 HOH   A O    1 
HETATM 9821  O  O    . HOH   M 5 .   ? 10.642  8.943   -5.403  1.00 46.82 ? 727 HOH   A O    1 
HETATM 9822  O  O    . HOH   M 5 .   ? 20.284  9.744   21.539  1.00 45.38 ? 728 HOH   A O    1 
HETATM 9823  O  O    . HOH   M 5 .   ? 17.423  37.213  14.360  1.00 44.03 ? 729 HOH   A O    1 
HETATM 9824  O  O    . HOH   M 5 .   ? 36.949  6.941   1.292   1.00 45.18 ? 730 HOH   A O    1 
HETATM 9825  O  O    . HOH   M 5 .   ? 29.158  16.819  1.200   1.00 19.92 ? 731 HOH   A O    1 
HETATM 9826  O  O    . HOH   M 5 .   ? 33.299  15.553  20.381  1.00 40.39 ? 732 HOH   A O    1 
HETATM 9827  O  O    . HOH   M 5 .   ? 17.457  -4.767  -6.730  1.00 45.60 ? 733 HOH   A O    1 
HETATM 9828  O  O    . HOH   M 5 .   ? 20.426  -1.500  12.100  1.00 37.04 ? 734 HOH   A O    1 
HETATM 9829  O  O    . HOH   M 5 .   ? 22.137  -0.054  11.784  1.00 36.84 ? 735 HOH   A O    1 
HETATM 9830  O  O    . HOH   M 5 .   ? 9.972   -6.371  13.836  1.00 31.54 ? 736 HOH   A O    1 
HETATM 9831  O  O    . HOH   M 5 .   ? 6.077   14.984  18.538  1.00 39.14 ? 737 HOH   A O    1 
HETATM 9832  O  O    . HOH   M 5 .   ? -11.217 31.626  14.382  1.00 42.31 ? 738 HOH   A O    1 
HETATM 9833  O  O    . HOH   M 5 .   ? 13.672  -21.854 -4.557  1.00 58.93 ? 739 HOH   A O    1 
HETATM 9834  O  O    . HOH   M 5 .   ? -9.145  19.971  12.360  1.00 42.40 ? 740 HOH   A O    1 
HETATM 9835  O  O    . HOH   M 5 .   ? 16.557  -16.742 -8.424  1.00 48.14 ? 741 HOH   A O    1 
HETATM 9836  O  O    . HOH   M 5 .   ? 1.889   22.727  26.493  1.00 46.49 ? 742 HOH   A O    1 
HETATM 9837  O  O    . HOH   M 5 .   ? 4.743   22.126  3.085   1.00 33.14 ? 743 HOH   A O    1 
HETATM 9838  O  O    . HOH   M 5 .   ? 1.045   26.221  7.204   1.00 34.59 ? 744 HOH   A O    1 
HETATM 9839  O  O    . HOH   M 5 .   ? 15.356  36.238  14.699  1.00 44.02 ? 745 HOH   A O    1 
HETATM 9840  O  O    . HOH   M 5 .   ? -3.317  25.774  5.858   1.00 49.07 ? 746 HOH   A O    1 
HETATM 9841  O  O    . HOH   M 5 .   ? 38.303  13.031  4.803   1.00 37.45 ? 747 HOH   A O    1 
HETATM 9842  O  O    . HOH   M 5 .   ? 1.496   24.367  5.057   1.00 37.43 ? 748 HOH   A O    1 
HETATM 9843  O  O    . HOH   M 5 .   ? -4.687  28.126  6.217   1.00 42.07 ? 749 HOH   A O    1 
HETATM 9844  O  O    . HOH   M 5 .   ? 29.787  11.981  20.826  1.00 45.01 ? 750 HOH   A O    1 
HETATM 9845  O  O    . HOH   M 5 .   ? 12.023  24.809  -10.772 1.00 43.66 ? 751 HOH   A O    1 
HETATM 9846  O  O    . HOH   M 5 .   ? 31.167  -28.642 -4.165  1.00 57.01 ? 752 HOH   A O    1 
HETATM 9847  O  O    . HOH   M 5 .   ? 36.428  8.945   8.821   1.00 42.12 ? 753 HOH   A O    1 
HETATM 9848  O  O    . HOH   M 5 .   ? 19.082  -18.041 -9.541  1.00 47.52 ? 754 HOH   A O    1 
HETATM 9849  O  O    . HOH   M 5 .   ? 7.784   28.535  -2.305  1.00 31.78 ? 755 HOH   A O    1 
HETATM 9850  O  O    . HOH   M 5 .   ? 35.661  7.251   10.011  1.00 57.87 ? 756 HOH   A O    1 
HETATM 9851  O  O    . HOH   M 5 .   ? 30.395  -28.157 -6.830  1.00 58.09 ? 757 HOH   A O    1 
HETATM 9852  O  O    . HOH   M 5 .   ? 24.240  -8.701  7.443   1.00 47.28 ? 758 HOH   A O    1 
HETATM 9853  O  O    . HOH   M 5 .   ? 7.764   23.783  -4.244  1.00 51.42 ? 759 HOH   A O    1 
HETATM 9854  O  O    . HOH   M 5 .   ? 10.009  24.226  -9.627  1.00 54.17 ? 760 HOH   A O    1 
HETATM 9855  O  O    . HOH   M 5 .   ? 31.183  2.064   8.194   1.00 51.18 ? 761 HOH   A O    1 
HETATM 9856  O  O    . HOH   M 5 .   ? 22.895  -11.405 14.470  1.00 46.99 ? 762 HOH   A O    1 
HETATM 9857  O  O    . HOH   M 5 .   ? -7.478  33.878  16.335  1.00 48.22 ? 763 HOH   A O    1 
HETATM 9858  O  O    . HOH   M 5 .   ? 18.150  29.134  -7.142  1.00 28.57 ? 764 HOH   A O    1 
HETATM 9859  O  O    . HOH   M 5 .   ? 35.747  18.081  13.175  1.00 46.98 ? 765 HOH   A O    1 
HETATM 9860  O  O    . HOH   M 5 .   ? 24.514  -29.717 8.583   1.00 59.03 ? 766 HOH   A O    1 
HETATM 9861  O  O    . HOH   M 5 .   ? 18.589  -0.117  -6.650  1.00 45.27 ? 767 HOH   A O    1 
HETATM 9862  O  O    . HOH   M 5 .   ? 33.860  7.495   -0.082  1.00 36.63 ? 768 HOH   A O    1 
HETATM 9863  O  O    . HOH   M 5 .   ? 3.521   24.824  27.879  1.00 33.53 ? 769 HOH   A O    1 
HETATM 9864  O  O    . HOH   M 5 .   ? 27.822  38.884  7.377   1.00 41.40 ? 770 HOH   A O    1 
HETATM 9865  O  O    . HOH   M 5 .   ? 14.082  31.078  -6.974  1.00 35.41 ? 771 HOH   A O    1 
HETATM 9866  O  O    . HOH   M 5 .   ? 6.272   38.198  16.917  1.00 53.70 ? 772 HOH   A O    1 
HETATM 9867  O  O    . HOH   M 5 .   ? 27.730  -13.301 11.479  1.00 43.42 ? 773 HOH   A O    1 
HETATM 9868  O  O    . HOH   M 5 .   ? 30.788  -9.540  3.468   1.00 49.87 ? 774 HOH   A O    1 
HETATM 9869  O  O    . HOH   M 5 .   ? 24.863  -14.942 14.244  1.00 37.41 ? 775 HOH   A O    1 
HETATM 9870  O  O    . HOH   M 5 .   ? 8.371   31.047  -2.840  1.00 47.88 ? 776 HOH   A O    1 
HETATM 9871  O  O    . HOH   M 5 .   ? 20.622  -3.058  14.672  1.00 46.39 ? 777 HOH   A O    1 
HETATM 9872  O  O    . HOH   M 5 .   ? 20.748  37.786  17.557  1.00 45.22 ? 778 HOH   A O    1 
HETATM 9873  O  O    . HOH   M 5 .   ? 37.585  13.001  8.280   1.00 42.27 ? 779 HOH   A O    1 
HETATM 9874  O  O    . HOH   M 5 .   ? 12.690  33.760  -0.297  1.00 42.41 ? 780 HOH   A O    1 
HETATM 9875  O  O    . HOH   M 5 .   ? -5.383  27.788  19.363  1.00 37.23 ? 781 HOH   A O    1 
HETATM 9876  O  O    . HOH   M 5 .   ? 14.973  35.253  16.669  1.00 40.77 ? 782 HOH   A O    1 
HETATM 9877  O  O    . HOH   M 5 .   ? 25.903  8.917   21.858  1.00 54.73 ? 783 HOH   A O    1 
HETATM 9878  O  O    . HOH   M 5 .   ? 14.215  33.173  1.657   1.00 30.14 ? 784 HOH   A O    1 
HETATM 9879  O  O    . HOH   M 5 .   ? 36.508  11.106  6.447   1.00 29.43 ? 785 HOH   A O    1 
HETATM 9880  O  O    . HOH   M 5 .   ? 14.317  -2.861  -8.382  1.00 45.16 ? 786 HOH   A O    1 
HETATM 9881  O  O    . HOH   M 5 .   ? 2.522   18.826  25.485  1.00 52.41 ? 787 HOH   A O    1 
HETATM 9882  O  O    . HOH   M 5 .   ? 6.799   33.489  22.337  1.00 34.69 ? 788 HOH   A O    1 
HETATM 9883  O  O    . HOH   M 5 .   ? 11.836  -5.658  16.158  1.00 38.92 ? 789 HOH   A O    1 
HETATM 9884  O  O    . HOH   M 5 .   ? 8.090   26.342  -4.344  1.00 45.82 ? 790 HOH   A O    1 
HETATM 9885  O  O    . HOH   M 5 .   ? 24.888  -16.733 15.625  1.00 43.01 ? 791 HOH   A O    1 
HETATM 9886  O  O    . HOH   N 5 .   ? 14.066  63.789  23.710  1.00 41.02 ? 501 HOH   B O    1 
HETATM 9887  O  O    . HOH   N 5 .   ? 6.427   36.971  27.654  1.00 44.81 ? 502 HOH   B O    1 
HETATM 9888  O  O    . HOH   N 5 .   ? 13.746  44.594  33.862  1.00 52.83 ? 503 HOH   B O    1 
HETATM 9889  O  O    . HOH   N 5 .   ? 24.453  6.798   49.578  1.00 37.98 ? 504 HOH   B O    1 
HETATM 9890  O  O    . HOH   N 5 .   ? 51.486  6.698   49.817  1.00 27.24 ? 505 HOH   B O    1 
HETATM 9891  O  O    . HOH   N 5 .   ? 8.761   4.552   47.706  1.00 46.34 ? 506 HOH   B O    1 
HETATM 9892  O  O    . HOH   N 5 .   ? 17.953  25.002  48.554  1.00 42.19 ? 507 HOH   B O    1 
HETATM 9893  O  O    . HOH   N 5 .   ? 32.534  5.865   33.837  1.00 45.44 ? 508 HOH   B O    1 
HETATM 9894  O  O    . HOH   N 5 .   ? 21.778  29.682  26.801  1.00 21.49 ? 509 HOH   B O    1 
HETATM 9895  O  O    . HOH   N 5 .   ? 11.229  60.120  41.282  1.00 48.58 ? 510 HOH   B O    1 
HETATM 9896  O  O    . HOH   N 5 .   ? 28.023  26.450  23.125  1.00 39.97 ? 511 HOH   B O    1 
HETATM 9897  O  O    . HOH   N 5 .   ? 19.708  20.584  18.522  1.00 31.86 ? 512 HOH   B O    1 
HETATM 9898  O  O    . HOH   N 5 .   ? 6.585   31.507  39.315  1.00 34.32 ? 513 HOH   B O    1 
HETATM 9899  O  O    . HOH   N 5 .   ? 29.592  45.679  29.638  1.00 37.98 ? 514 HOH   B O    1 
HETATM 9900  O  O    . HOH   N 5 .   ? 33.058  -2.443  48.893  1.00 44.61 ? 515 HOH   B O    1 
HETATM 9901  O  O    . HOH   N 5 .   ? 21.472  6.484   47.161  1.00 28.99 ? 516 HOH   B O    1 
HETATM 9902  O  O    . HOH   N 5 .   ? 19.041  -0.579  39.392  1.00 47.70 ? 517 HOH   B O    1 
HETATM 9903  O  O    . HOH   N 5 .   ? 10.825  57.027  40.454  1.00 39.61 ? 518 HOH   B O    1 
HETATM 9904  O  O    . HOH   N 5 .   ? 32.807  3.850   51.658  1.00 25.45 ? 519 HOH   B O    1 
HETATM 9905  O  O    . HOH   N 5 .   ? 27.806  53.663  30.358  1.00 42.66 ? 520 HOH   B O    1 
HETATM 9906  O  O    . HOH   N 5 .   ? 34.393  6.335   37.939  1.00 33.21 ? 521 HOH   B O    1 
HETATM 9907  O  O    . HOH   N 5 .   ? 24.939  17.726  32.526  1.00 19.11 ? 522 HOH   B O    1 
HETATM 9908  O  O    . HOH   N 5 .   ? 13.089  20.309  30.451  1.00 27.47 ? 523 HOH   B O    1 
HETATM 9909  O  O    . HOH   N 5 .   ? 11.387  10.862  31.064  1.00 43.64 ? 524 HOH   B O    1 
HETATM 9910  O  O    . HOH   N 5 .   ? 15.023  23.287  49.200  1.00 20.41 ? 525 HOH   B O    1 
HETATM 9911  O  O    . HOH   N 5 .   ? 38.795  11.770  42.045  1.00 42.23 ? 526 HOH   B O    1 
HETATM 9912  O  O    . HOH   N 5 .   ? 26.736  9.041   26.608  1.00 25.38 ? 527 HOH   B O    1 
HETATM 9913  O  O    . HOH   N 5 .   ? 8.787   28.302  44.104  1.00 42.86 ? 528 HOH   B O    1 
HETATM 9914  O  O    . HOH   N 5 .   ? 20.545  40.405  41.738  1.00 28.68 ? 529 HOH   B O    1 
HETATM 9915  O  O    . HOH   N 5 .   ? 11.600  53.361  26.284  1.00 45.19 ? 530 HOH   B O    1 
HETATM 9916  O  O    . HOH   N 5 .   ? 8.582   10.214  36.478  1.00 38.98 ? 531 HOH   B O    1 
HETATM 9917  O  O    . HOH   N 5 .   ? 32.690  32.162  32.105  1.00 44.49 ? 532 HOH   B O    1 
HETATM 9918  O  O    . HOH   N 5 .   ? 12.966  48.475  28.441  1.00 46.95 ? 533 HOH   B O    1 
HETATM 9919  O  O    . HOH   N 5 .   ? 19.474  33.867  48.228  1.00 44.33 ? 534 HOH   B O    1 
HETATM 9920  O  O    . HOH   N 5 .   ? 53.624  3.420   36.889  1.00 50.76 ? 535 HOH   B O    1 
HETATM 9921  O  O    . HOH   N 5 .   ? 28.722  16.933  31.496  1.00 19.87 ? 536 HOH   B O    1 
HETATM 9922  O  O    . HOH   N 5 .   ? 18.622  21.758  22.417  1.00 29.65 ? 537 HOH   B O    1 
HETATM 9923  O  O    . HOH   N 5 .   ? 15.425  14.417  27.667  1.00 25.99 ? 538 HOH   B O    1 
HETATM 9924  O  O    . HOH   N 5 .   ? 30.652  41.809  48.011  1.00 36.08 ? 539 HOH   B O    1 
HETATM 9925  O  O    . HOH   N 5 .   ? 18.349  47.676  32.505  1.00 39.06 ? 540 HOH   B O    1 
HETATM 9926  O  O    . HOH   N 5 .   ? 24.613  51.042  49.967  1.00 45.65 ? 541 HOH   B O    1 
HETATM 9927  O  O    . HOH   N 5 .   ? 10.952  3.867   42.590  1.00 34.06 ? 542 HOH   B O    1 
HETATM 9928  O  O    . HOH   N 5 .   ? 36.174  16.261  41.967  1.00 40.50 ? 543 HOH   B O    1 
HETATM 9929  O  O    . HOH   N 5 .   ? 15.389  50.760  40.693  1.00 28.93 ? 544 HOH   B O    1 
HETATM 9930  O  O    . HOH   N 5 .   ? 23.508  18.943  55.257  1.00 26.55 ? 545 HOH   B O    1 
HETATM 9931  O  O    . HOH   N 5 .   ? 29.799  16.194  38.517  1.00 22.04 ? 546 HOH   B O    1 
HETATM 9932  O  O    . HOH   N 5 .   ? 13.252  54.179  39.663  1.00 27.28 ? 547 HOH   B O    1 
HETATM 9933  O  O    . HOH   N 5 .   ? 9.635   17.533  25.728  1.00 40.00 ? 548 HOH   B O    1 
HETATM 9934  O  O    . HOH   N 5 .   ? 7.608   36.332  32.953  1.00 39.07 ? 549 HOH   B O    1 
HETATM 9935  O  O    . HOH   N 5 .   ? 26.701  15.494  33.010  1.00 20.52 ? 550 HOH   B O    1 
HETATM 9936  O  O    . HOH   N 5 .   ? 25.273  9.387   52.978  1.00 31.64 ? 551 HOH   B O    1 
HETATM 9937  O  O    . HOH   N 5 .   ? 18.507  5.541   42.371  1.00 32.56 ? 552 HOH   B O    1 
HETATM 9938  O  O    . HOH   N 5 .   ? 44.241  8.575   45.994  1.00 32.08 ? 553 HOH   B O    1 
HETATM 9939  O  O    . HOH   N 5 .   ? 19.253  12.495  48.703  1.00 29.14 ? 554 HOH   B O    1 
HETATM 9940  O  O    . HOH   N 5 .   ? 25.788  24.792  22.516  1.00 40.39 ? 555 HOH   B O    1 
HETATM 9941  O  O    . HOH   N 5 .   ? 21.577  44.265  39.596  1.00 34.73 ? 556 HOH   B O    1 
HETATM 9942  O  O    . HOH   N 5 .   ? 28.371  6.713   31.033  1.00 32.42 ? 557 HOH   B O    1 
HETATM 9943  O  O    . HOH   N 5 .   ? 16.470  14.888  49.082  1.00 37.20 ? 558 HOH   B O    1 
HETATM 9944  O  O    . HOH   N 5 .   ? 44.485  12.448  52.436  1.00 33.05 ? 559 HOH   B O    1 
HETATM 9945  O  O    . HOH   N 5 .   ? 39.231  3.107   54.456  1.00 46.23 ? 560 HOH   B O    1 
HETATM 9946  O  O    . HOH   N 5 .   ? 16.248  70.775  21.090  1.00 43.22 ? 561 HOH   B O    1 
HETATM 9947  O  O    . HOH   N 5 .   ? 12.356  32.508  21.792  1.00 42.37 ? 562 HOH   B O    1 
HETATM 9948  O  O    . HOH   N 5 .   ? 12.057  7.022   30.422  1.00 51.79 ? 563 HOH   B O    1 
HETATM 9949  O  O    . HOH   N 5 .   ? 19.056  17.967  37.764  1.00 24.79 ? 564 HOH   B O    1 
HETATM 9950  O  O    . HOH   N 5 .   ? 21.085  41.696  39.668  1.00 35.04 ? 565 HOH   B O    1 
HETATM 9951  O  O    . HOH   N 5 .   ? 14.759  69.010  24.861  1.00 37.10 ? 566 HOH   B O    1 
HETATM 9952  O  O    . HOH   N 5 .   ? 30.752  18.661  29.546  1.00 28.08 ? 567 HOH   B O    1 
HETATM 9953  O  O    . HOH   N 5 .   ? 25.037  51.601  41.412  1.00 30.36 ? 568 HOH   B O    1 
HETATM 9954  O  O    . HOH   N 5 .   ? 3.098   24.660  33.769  1.00 37.27 ? 569 HOH   B O    1 
HETATM 9955  O  O    . HOH   N 5 .   ? 27.992  24.654  29.024  1.00 24.38 ? 570 HOH   B O    1 
HETATM 9956  O  O    . HOH   N 5 .   ? 42.266  14.535  55.187  1.00 37.34 ? 571 HOH   B O    1 
HETATM 9957  O  O    . HOH   N 5 .   ? 30.485  13.921  43.833  1.00 21.02 ? 572 HOH   B O    1 
HETATM 9958  O  O    . HOH   N 5 .   ? 27.206  47.261  45.275  1.00 26.34 ? 573 HOH   B O    1 
HETATM 9959  O  O    . HOH   N 5 .   ? 25.336  8.074   32.953  1.00 29.23 ? 574 HOH   B O    1 
HETATM 9960  O  O    . HOH   N 5 .   ? 7.375   15.483  32.171  1.00 27.96 ? 575 HOH   B O    1 
HETATM 9961  O  O    . HOH   N 5 .   ? 26.705  36.061  28.159  1.00 29.82 ? 576 HOH   B O    1 
HETATM 9962  O  O    . HOH   N 5 .   ? 23.195  11.414  25.025  1.00 33.90 ? 577 HOH   B O    1 
HETATM 9963  O  O    . HOH   N 5 .   ? 22.981  10.689  51.319  1.00 38.15 ? 578 HOH   B O    1 
HETATM 9964  O  O    . HOH   N 5 .   ? 11.485  49.793  34.326  1.00 59.59 ? 579 HOH   B O    1 
HETATM 9965  O  O    . HOH   N 5 .   ? 27.353  25.711  25.410  1.00 33.85 ? 580 HOH   B O    1 
HETATM 9966  O  O    . HOH   N 5 .   ? 21.757  68.855  22.225  1.00 43.38 ? 581 HOH   B O    1 
HETATM 9967  O  O    . HOH   N 5 .   ? 32.243  25.015  34.187  1.00 36.84 ? 582 HOH   B O    1 
HETATM 9968  O  O    . HOH   N 5 .   ? 19.564  44.326  25.123  1.00 41.10 ? 583 HOH   B O    1 
HETATM 9969  O  O    . HOH   N 5 .   ? 8.057   15.371  29.385  1.00 34.48 ? 584 HOH   B O    1 
HETATM 9970  O  O    . HOH   N 5 .   ? 28.817  4.579   57.198  1.00 40.64 ? 585 HOH   B O    1 
HETATM 9971  O  O    . HOH   N 5 .   ? 33.099  35.489  37.417  1.00 52.42 ? 586 HOH   B O    1 
HETATM 9972  O  O    . HOH   N 5 .   ? 12.692  24.909  29.821  1.00 18.45 ? 587 HOH   B O    1 
HETATM 9973  O  O    . HOH   N 5 .   ? 18.977  30.357  26.379  1.00 21.50 ? 588 HOH   B O    1 
HETATM 9974  O  O    . HOH   N 5 .   ? 12.542  11.295  27.701  1.00 43.38 ? 589 HOH   B O    1 
HETATM 9975  O  O    . HOH   N 5 .   ? 4.368   27.020  44.115  1.00 43.90 ? 590 HOH   B O    1 
HETATM 9976  O  O    . HOH   N 5 .   ? 12.644  2.820   39.359  1.00 38.19 ? 591 HOH   B O    1 
HETATM 9977  O  O    . HOH   N 5 .   ? 11.941  11.195  48.220  1.00 23.09 ? 592 HOH   B O    1 
HETATM 9978  O  O    . HOH   N 5 .   ? 26.140  14.858  60.519  1.00 21.33 ? 593 HOH   B O    1 
HETATM 9979  O  O    . HOH   N 5 .   ? 34.421  46.825  38.692  1.00 44.83 ? 594 HOH   B O    1 
HETATM 9980  O  O    . HOH   N 5 .   ? 44.106  17.086  46.581  1.00 43.23 ? 595 HOH   B O    1 
HETATM 9981  O  O    . HOH   N 5 .   ? 13.674  16.652  46.329  1.00 26.46 ? 596 HOH   B O    1 
HETATM 9982  O  O    . HOH   N 5 .   ? 16.798  49.250  34.176  1.00 31.35 ? 597 HOH   B O    1 
HETATM 9983  O  O    . HOH   N 5 .   ? 27.244  27.100  49.953  1.00 40.71 ? 598 HOH   B O    1 
HETATM 9984  O  O    . HOH   N 5 .   ? 12.768  21.071  33.211  1.00 21.91 ? 599 HOH   B O    1 
HETATM 9985  O  O    . HOH   N 5 .   ? 30.279  28.728  24.902  1.00 40.64 ? 600 HOH   B O    1 
HETATM 9986  O  O    . HOH   N 5 .   ? 21.668  20.134  50.284  1.00 28.42 ? 601 HOH   B O    1 
HETATM 9987  O  O    . HOH   N 5 .   ? 33.977  37.474  29.094  1.00 51.52 ? 602 HOH   B O    1 
HETATM 9988  O  O    . HOH   N 5 .   ? 34.865  23.251  26.732  1.00 39.59 ? 603 HOH   B O    1 
HETATM 9989  O  O    . HOH   N 5 .   ? 33.640  27.916  45.609  1.00 42.65 ? 604 HOH   B O    1 
HETATM 9990  O  O    . HOH   N 5 .   ? 31.606  36.206  33.053  1.00 43.69 ? 605 HOH   B O    1 
HETATM 9991  O  O    . HOH   N 5 .   ? 34.770  -1.067  60.107  1.00 57.91 ? 606 HOH   B O    1 
HETATM 9992  O  O    . HOH   N 5 .   ? 31.295  3.229   37.479  1.00 45.24 ? 607 HOH   B O    1 
HETATM 9993  O  O    . HOH   N 5 .   ? 24.670  37.695  27.100  1.00 26.88 ? 608 HOH   B O    1 
HETATM 9994  O  O    . HOH   N 5 .   ? 23.300  25.555  21.079  1.00 26.70 ? 609 HOH   B O    1 
HETATM 9995  O  O    . HOH   N 5 .   ? 36.314  46.857  34.949  1.00 53.68 ? 610 HOH   B O    1 
HETATM 9996  O  O    . HOH   N 5 .   ? 0.703   15.054  41.989  1.00 49.53 ? 611 HOH   B O    1 
HETATM 9997  O  O    . HOH   N 5 .   ? 39.343  10.609  56.859  1.00 47.07 ? 612 HOH   B O    1 
HETATM 9998  O  O    . HOH   N 5 .   ? 7.423   26.210  24.821  1.00 22.97 ? 613 HOH   B O    1 
HETATM 9999  O  O    . HOH   N 5 .   ? 38.117  8.724   38.636  1.00 52.60 ? 614 HOH   B O    1 
HETATM 10000 O  O    . HOH   N 5 .   ? 2.144   24.483  36.409  1.00 44.25 ? 615 HOH   B O    1 
HETATM 10001 O  O    . HOH   N 5 .   ? 35.688  10.072  34.281  1.00 43.14 ? 616 HOH   B O    1 
HETATM 10002 O  O    . HOH   N 5 .   ? 10.771  45.653  30.383  1.00 51.64 ? 617 HOH   B O    1 
HETATM 10003 O  O    . HOH   N 5 .   ? 13.265  74.360  27.704  1.00 38.23 ? 618 HOH   B O    1 
HETATM 10004 O  O    . HOH   N 5 .   ? 22.365  64.863  39.739  1.00 46.66 ? 619 HOH   B O    1 
HETATM 10005 O  O    . HOH   N 5 .   ? 20.318  26.923  49.007  1.00 41.91 ? 620 HOH   B O    1 
HETATM 10006 O  O    . HOH   N 5 .   ? 26.979  5.364   36.584  1.00 27.61 ? 621 HOH   B O    1 
HETATM 10007 O  O    . HOH   N 5 .   ? 45.657  4.756   52.154  1.00 33.03 ? 622 HOH   B O    1 
HETATM 10008 O  O    . HOH   N 5 .   ? 15.554  72.823  31.009  1.00 37.18 ? 623 HOH   B O    1 
HETATM 10009 O  O    . HOH   N 5 .   ? 33.441  32.939  45.449  1.00 43.09 ? 624 HOH   B O    1 
HETATM 10010 O  O    . HOH   N 5 .   ? 28.362  48.496  47.346  1.00 42.13 ? 625 HOH   B O    1 
HETATM 10011 O  O    . HOH   N 5 .   ? 22.498  18.658  57.410  1.00 42.18 ? 626 HOH   B O    1 
HETATM 10012 O  O    . HOH   N 5 .   ? 9.495   30.717  28.529  1.00 21.58 ? 627 HOH   B O    1 
HETATM 10013 O  O    . HOH   N 5 .   ? 13.694  38.647  38.150  1.00 28.56 ? 628 HOH   B O    1 
HETATM 10014 O  O    . HOH   N 5 .   ? 21.167  10.033  26.044  1.00 27.95 ? 629 HOH   B O    1 
HETATM 10015 O  O    . HOH   N 5 .   ? 15.773  36.432  39.727  1.00 23.68 ? 630 HOH   B O    1 
HETATM 10016 O  O    . HOH   N 5 .   ? 25.073  10.224  55.392  1.00 34.46 ? 631 HOH   B O    1 
HETATM 10017 O  O    . HOH   N 5 .   ? 30.922  24.641  52.822  1.00 44.23 ? 632 HOH   B O    1 
HETATM 10018 O  O    . HOH   N 5 .   ? 25.856  5.204   53.459  1.00 34.17 ? 633 HOH   B O    1 
HETATM 10019 O  O    . HOH   N 5 .   ? 8.065   23.770  28.552  1.00 21.57 ? 634 HOH   B O    1 
HETATM 10020 O  O    . HOH   N 5 .   ? 23.690  1.641   42.682  1.00 47.04 ? 635 HOH   B O    1 
HETATM 10021 O  O    . HOH   N 5 .   ? 10.508  67.563  30.802  1.00 51.42 ? 636 HOH   B O    1 
HETATM 10022 O  O    . HOH   N 5 .   ? 21.169  6.323   42.314  1.00 29.20 ? 637 HOH   B O    1 
HETATM 10023 O  O    . HOH   N 5 .   ? 12.419  29.622  21.409  1.00 28.94 ? 638 HOH   B O    1 
HETATM 10024 O  O    . HOH   N 5 .   ? 12.582  2.787   46.361  1.00 44.29 ? 639 HOH   B O    1 
HETATM 10025 O  O    . HOH   N 5 .   ? 16.524  62.197  43.958  1.00 40.84 ? 640 HOH   B O    1 
HETATM 10026 O  O    . HOH   N 5 .   ? 27.403  26.506  31.074  1.00 23.60 ? 641 HOH   B O    1 
HETATM 10027 O  O    . HOH   N 5 .   ? 2.496   29.061  37.841  1.00 43.08 ? 642 HOH   B O    1 
HETATM 10028 O  O    . HOH   N 5 .   ? 19.328  41.476  24.049  1.00 35.70 ? 643 HOH   B O    1 
HETATM 10029 O  O    . HOH   N 5 .   ? 3.208   7.821   41.286  1.00 42.29 ? 644 HOH   B O    1 
HETATM 10030 O  O    . HOH   N 5 .   ? 14.529  12.828  47.951  1.00 35.78 ? 645 HOH   B O    1 
HETATM 10031 O  O    . HOH   N 5 .   ? 40.975  20.141  46.381  1.00 33.49 ? 646 HOH   B O    1 
HETATM 10032 O  O    . HOH   N 5 .   ? 32.384  35.105  44.365  1.00 34.84 ? 647 HOH   B O    1 
HETATM 10033 O  O    . HOH   N 5 .   ? 6.148   33.876  34.713  1.00 32.40 ? 648 HOH   B O    1 
HETATM 10034 O  O    . HOH   N 5 .   ? 20.691  30.404  49.802  1.00 41.21 ? 649 HOH   B O    1 
HETATM 10035 O  O    . HOH   N 5 .   ? 3.341   24.631  42.783  1.00 42.39 ? 650 HOH   B O    1 
HETATM 10036 O  O    . HOH   N 5 .   ? 7.607   10.463  34.237  1.00 42.39 ? 651 HOH   B O    1 
HETATM 10037 O  O    . HOH   N 5 .   ? 35.791  13.470  38.818  1.00 32.67 ? 652 HOH   B O    1 
HETATM 10038 O  O    . HOH   N 5 .   ? 22.948  3.227   28.031  1.00 33.56 ? 653 HOH   B O    1 
HETATM 10039 O  O    . HOH   N 5 .   ? 41.919  5.446   53.796  1.00 37.63 ? 654 HOH   B O    1 
HETATM 10040 O  O    . HOH   N 5 .   ? 34.002  19.384  23.054  1.00 45.85 ? 655 HOH   B O    1 
HETATM 10041 O  O    . HOH   N 5 .   ? 17.311  44.225  36.962  1.00 38.08 ? 656 HOH   B O    1 
HETATM 10042 O  O    . HOH   N 5 .   ? 26.332  9.156   57.643  1.00 36.94 ? 657 HOH   B O    1 
HETATM 10043 O  O    . HOH   N 5 .   ? 2.216   21.753  39.608  1.00 44.31 ? 658 HOH   B O    1 
HETATM 10044 O  O    . HOH   N 5 .   ? 26.632  49.271  48.589  1.00 45.80 ? 659 HOH   B O    1 
HETATM 10045 O  O    . HOH   N 5 .   ? 5.251   31.967  26.018  1.00 45.41 ? 660 HOH   B O    1 
HETATM 10046 O  O    . HOH   N 5 .   ? 11.089  37.098  36.632  1.00 30.08 ? 661 HOH   B O    1 
HETATM 10047 O  O    . HOH   N 5 .   ? 15.302  48.091  36.421  1.00 49.38 ? 662 HOH   B O    1 
HETATM 10048 O  O    . HOH   N 5 .   ? 45.570  14.700  49.316  1.00 33.89 ? 663 HOH   B O    1 
HETATM 10049 O  O    . HOH   N 5 .   ? 28.350  19.329  55.779  1.00 38.10 ? 664 HOH   B O    1 
HETATM 10050 O  O    . HOH   N 5 .   ? 1.936   18.962  32.304  1.00 44.26 ? 665 HOH   B O    1 
HETATM 10051 O  O    . HOH   N 5 .   ? 30.719  44.903  33.740  1.00 43.73 ? 666 HOH   B O    1 
HETATM 10052 O  O    . HOH   N 5 .   ? 24.136  61.268  41.508  1.00 43.15 ? 667 HOH   B O    1 
HETATM 10053 O  O    . HOH   N 5 .   ? 18.149  45.819  23.263  1.00 40.93 ? 668 HOH   B O    1 
HETATM 10054 O  O    . HOH   N 5 .   ? 28.549  7.834   58.124  1.00 35.07 ? 669 HOH   B O    1 
HETATM 10055 O  O    . HOH   N 5 .   ? 7.110   35.012  37.126  1.00 41.02 ? 670 HOH   B O    1 
HETATM 10056 O  O    . HOH   N 5 .   ? 33.431  0.119   38.586  1.00 46.45 ? 671 HOH   B O    1 
HETATM 10057 O  O    . HOH   N 5 .   ? 25.864  21.428  58.626  1.00 46.65 ? 672 HOH   B O    1 
HETATM 10058 O  O    . HOH   N 5 .   ? 12.709  51.585  36.509  1.00 37.99 ? 673 HOH   B O    1 
HETATM 10059 O  O    . HOH   N 5 .   ? 9.981   21.700  27.914  1.00 23.83 ? 674 HOH   B O    1 
HETATM 10060 O  O    . HOH   N 5 .   ? 1.744   11.770  34.981  1.00 40.66 ? 675 HOH   B O    1 
HETATM 10061 O  O    . HOH   N 5 .   ? 47.664  6.990   51.949  1.00 27.58 ? 676 HOH   B O    1 
HETATM 10062 O  O    . HOH   N 5 .   ? 36.507  25.545  45.665  1.00 38.07 ? 677 HOH   B O    1 
HETATM 10063 O  O    . HOH   N 5 .   ? 23.338  5.658   44.944  1.00 23.30 ? 678 HOH   B O    1 
HETATM 10064 O  O    . HOH   N 5 .   ? 50.432  1.214   50.564  1.00 34.72 ? 679 HOH   B O    1 
HETATM 10065 O  O    . HOH   N 5 .   ? 19.472  9.752   23.744  1.00 32.95 ? 680 HOH   B O    1 
HETATM 10066 O  O    . HOH   N 5 .   ? 15.493  0.439   29.776  1.00 47.82 ? 681 HOH   B O    1 
HETATM 10067 O  O    . HOH   N 5 .   ? 12.220  73.718  19.971  1.00 40.18 ? 682 HOH   B O    1 
HETATM 10068 O  O    . HOH   N 5 .   ? 32.263  16.957  37.356  1.00 29.34 ? 683 HOH   B O    1 
HETATM 10069 O  O    . HOH   N 5 .   ? 10.577  4.779   32.934  1.00 38.48 ? 684 HOH   B O    1 
HETATM 10070 O  O    . HOH   N 5 .   ? 14.425  40.575  23.444  1.00 46.86 ? 685 HOH   B O    1 
HETATM 10071 O  O    . HOH   N 5 .   ? 23.331  64.952  36.519  1.00 48.76 ? 686 HOH   B O    1 
HETATM 10072 O  O    . HOH   N 5 .   ? 1.148   11.393  44.818  1.00 47.13 ? 687 HOH   B O    1 
HETATM 10073 O  O    . HOH   N 5 .   ? 15.432  45.638  22.694  1.00 50.55 ? 688 HOH   B O    1 
HETATM 10074 O  O    . HOH   N 5 .   ? 26.042  20.736  55.503  1.00 39.87 ? 689 HOH   B O    1 
HETATM 10075 O  O    . HOH   N 5 .   ? 29.928  54.294  30.683  1.00 54.43 ? 690 HOH   B O    1 
HETATM 10076 O  O    . HOH   N 5 .   ? 31.967  17.424  27.859  1.00 32.50 ? 691 HOH   B O    1 
HETATM 10077 O  O    . HOH   N 5 .   ? 22.474  32.818  48.407  1.00 29.14 ? 692 HOH   B O    1 
HETATM 10078 O  O    . HOH   N 5 .   ? 28.376  35.423  26.226  1.00 36.69 ? 693 HOH   B O    1 
HETATM 10079 O  O    . HOH   N 5 .   ? 34.825  4.214   36.769  1.00 48.49 ? 694 HOH   B O    1 
HETATM 10080 O  O    . HOH   N 5 .   ? 22.345  36.843  25.615  1.00 30.05 ? 695 HOH   B O    1 
HETATM 10081 O  O    . HOH   N 5 .   ? 47.381  -2.953  48.362  1.00 50.97 ? 696 HOH   B O    1 
HETATM 10082 O  O    . HOH   N 5 .   ? 29.319  4.530   34.847  1.00 47.02 ? 697 HOH   B O    1 
HETATM 10083 O  O    . HOH   N 5 .   ? 36.384  13.017  43.527  1.00 40.96 ? 698 HOH   B O    1 
HETATM 10084 O  O    . HOH   N 5 .   ? 15.764  12.091  20.706  1.00 46.34 ? 699 HOH   B O    1 
HETATM 10085 O  O    . HOH   N 5 .   ? 18.185  10.143  49.952  1.00 46.16 ? 700 HOH   B O    1 
HETATM 10086 O  O    . HOH   N 5 .   ? 13.395  42.520  35.410  1.00 48.59 ? 701 HOH   B O    1 
HETATM 10087 O  O    . HOH   N 5 .   ? 22.145  3.518   43.820  1.00 46.04 ? 702 HOH   B O    1 
HETATM 10088 O  O    . HOH   N 5 .   ? 20.312  22.485  20.130  1.00 36.57 ? 703 HOH   B O    1 
HETATM 10089 O  O    . HOH   N 5 .   ? 17.551  40.181  41.849  1.00 42.39 ? 704 HOH   B O    1 
HETATM 10090 O  O    . HOH   N 5 .   ? 17.366  22.827  50.474  1.00 40.80 ? 705 HOH   B O    1 
HETATM 10091 O  O    . HOH   N 5 .   ? 31.539  7.724   26.843  1.00 46.59 ? 706 HOH   B O    1 
HETATM 10092 O  O    . HOH   N 5 .   ? 35.616  16.820  35.700  1.00 53.60 ? 707 HOH   B O    1 
HETATM 10093 O  O    . HOH   N 5 .   ? 24.752  10.285  20.353  1.00 55.21 ? 708 HOH   B O    1 
HETATM 10094 O  O    . HOH   N 5 .   ? 30.513  16.281  61.276  1.00 50.84 ? 709 HOH   B O    1 
HETATM 10095 O  O    . HOH   N 5 .   ? 26.728  3.894   38.516  1.00 38.15 ? 710 HOH   B O    1 
HETATM 10096 O  O    . HOH   N 5 .   ? 31.553  26.614  24.475  1.00 46.09 ? 711 HOH   B O    1 
HETATM 10097 O  O    . HOH   N 5 .   ? 12.459  22.383  28.806  1.00 19.44 ? 712 HOH   B O    1 
HETATM 10098 O  O    . HOH   N 5 .   ? 15.068  16.572  49.691  1.00 40.88 ? 713 HOH   B O    1 
HETATM 10099 O  O    . HOH   N 5 .   ? 30.303  27.526  32.166  1.00 50.59 ? 714 HOH   B O    1 
HETATM 10100 O  O    . HOH   N 5 .   ? 26.839  45.127  46.940  1.00 36.33 ? 715 HOH   B O    1 
HETATM 10101 O  O    . HOH   N 5 .   ? 22.316  7.604   49.270  1.00 45.46 ? 716 HOH   B O    1 
HETATM 10102 O  O    . HOH   N 5 .   ? 36.936  14.086  41.278  1.00 48.36 ? 717 HOH   B O    1 
HETATM 10103 O  O    . HOH   N 5 .   ? 21.859  7.737   26.500  1.00 41.02 ? 718 HOH   B O    1 
HETATM 10104 O  O    . HOH   N 5 .   ? 34.556  16.292  38.526  1.00 35.48 ? 719 HOH   B O    1 
HETATM 10105 O  O    . HOH   N 5 .   ? 0.625   27.449  39.048  1.00 50.48 ? 720 HOH   B O    1 
HETATM 10106 O  O    . HOH   N 5 .   ? 32.342  28.617  32.197  1.00 50.78 ? 721 HOH   B O    1 
HETATM 10107 O  O    . HOH   N 5 .   ? 17.058  32.987  49.273  1.00 52.05 ? 722 HOH   B O    1 
HETATM 10108 O  O    . HOH   N 5 .   ? 3.390   30.782  33.608  1.00 47.81 ? 723 HOH   B O    1 
HETATM 10109 O  O    . HOH   N 5 .   ? 8.931   6.354   33.181  1.00 54.57 ? 724 HOH   B O    1 
HETATM 10110 O  O    . HOH   N 5 .   ? 21.789  37.966  23.524  1.00 45.64 ? 725 HOH   B O    1 
HETATM 10111 O  O    . HOH   N 5 .   ? 33.446  9.945   32.432  1.00 37.45 ? 726 HOH   B O    1 
HETATM 10112 O  O    . HOH   N 5 .   ? 31.828  13.397  22.679  1.00 48.16 ? 727 HOH   B O    1 
HETATM 10113 O  O    . HOH   N 5 .   ? 23.075  6.811   24.860  1.00 57.60 ? 728 HOH   B O    1 
HETATM 10114 O  O    . HOH   N 5 .   ? 9.168   77.290  26.414  1.00 44.18 ? 729 HOH   B O    1 
HETATM 10115 O  O    . HOH   N 5 .   ? 25.166  9.667   24.474  1.00 34.07 ? 730 HOH   B O    1 
HETATM 10116 O  O    . HOH   N 5 .   ? 28.332  14.757  62.370  1.00 35.98 ? 731 HOH   B O    1 
HETATM 10117 O  O    . HOH   N 5 .   ? 29.073  7.415   26.108  1.00 40.06 ? 732 HOH   B O    1 
HETATM 10118 O  O    . HOH   N 5 .   ? 12.970  54.091  42.370  1.00 40.79 ? 733 HOH   B O    1 
HETATM 10119 O  O    . HOH   N 5 .   ? 33.938  16.491  28.344  1.00 48.79 ? 734 HOH   B O    1 
HETATM 10120 O  O    . HOH   N 5 .   ? 11.046  48.864  30.318  1.00 49.35 ? 735 HOH   B O    1 
HETATM 10121 O  O    . HOH   N 5 .   ? 45.946  7.782   43.773  1.00 36.69 ? 736 HOH   B O    1 
HETATM 10122 O  O    . HOH   N 5 .   ? 2.448   26.358  29.238  1.00 44.26 ? 737 HOH   B O    1 
HETATM 10123 O  O    . HOH   N 5 .   ? 24.169  38.454  23.081  1.00 47.84 ? 738 HOH   B O    1 
HETATM 10124 O  O    . HOH   N 5 .   ? 33.050  7.291   31.571  1.00 40.14 ? 739 HOH   B O    1 
HETATM 10125 O  O    . HOH   N 5 .   ? 9.037   54.946  41.452  1.00 56.36 ? 740 HOH   B O    1 
HETATM 10126 O  O    . HOH   N 5 .   ? 2.417   26.745  32.278  1.00 43.74 ? 741 HOH   B O    1 
HETATM 10127 O  O    . HOH   N 5 .   ? 3.838   28.716  31.386  1.00 37.95 ? 742 HOH   B O    1 
HETATM 10128 O  O    . HOH   N 5 .   ? 38.093  47.491  42.161  1.00 56.68 ? 743 HOH   B O    1 
HETATM 10129 O  O    . HOH   N 5 .   ? 25.776  5.616   34.155  1.00 30.86 ? 744 HOH   B O    1 
HETATM 10130 O  O    . HOH   N 5 .   ? 38.424  49.719  40.983  1.00 60.36 ? 745 HOH   B O    1 
HETATM 10131 O  O    . HOH   N 5 .   ? 35.058  14.275  30.569  1.00 52.79 ? 746 HOH   B O    1 
HETATM 10132 O  O    . HOH   N 5 .   ? 33.761  11.936  30.437  1.00 41.48 ? 747 HOH   B O    1 
HETATM 10133 O  O    . HOH   N 5 .   ? 24.776  44.503  48.489  1.00 43.99 ? 748 HOH   B O    1 
# 
